BLASTP 2.2.22 [Sep-27-2009]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= batch____
         (224 letters)

Database: uniref50.fasta 
           3,077,464 sequences; 1,040,396,356 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q46898 Uncharacterized protein ygcI n=13 Tax=Proteobact...   462   e-129
UniRef50_C5SD48 CRISPR-associated protein Cas5 family n=1 Tax=Al...   155   8e-37
UniRef50_A1SV73 CRISPR-associated protein, Cas5e family n=2 Tax=...   119   7e-26
UniRef50_A6W168 CRISPR-associated protein Cas5 family n=6 Tax=Ga...   114   3e-24
UniRef50_Q1R114 CRISPR-associated protein, CT1976 n=1 Tax=Chromo...   112   1e-23
UniRef50_Q314I4 CRISPR-associated protein, CT1976 n=1 Tax=Desulf...   111   2e-23
UniRef50_Q04QB7 Putative uncharacterized protein n=2 Tax=Leptosp...   100   3e-20
UniRef50_C7MTB0 CRISPR-associated protein Cas5 n=1 Tax=Saccharom...   100   4e-20
UniRef50_B7KJ26 CRISPR-associated protein Cas5 family n=1 Tax=Cy...    97   3e-19
UniRef50_A8LYZ7 CRISPR-associated protein Cas5 family n=2 Tax=Ac...    97   4e-19
UniRef50_C7MQD6 CRISPR-associated protein Cas5 n=1 Tax=Saccharom...    95   2e-18
UniRef50_Q1EQS9 CRISPR-associated protein n=3 Tax=Streptomyces R...    95   2e-18
UniRef50_Q2RY19 CRISPR-associated protein, Cas5e family n=1 Tax=...    94   3e-18
UniRef50_C2BET8 CRISPR-associated protein n=2 Tax=Firmicutes Rep...    93   6e-18
UniRef50_A5UR14 CRISPR-associated protein, Cas5e family n=1 Tax=...    92   2e-17
UniRef50_Q12YA8 CRISPR-associated protein, CT1976-like n=1 Tax=M...    92   2e-17
UniRef50_D1A6Q5 CRISPR-associated protein Cas5 family n=2 Tax=Ac...    91   3e-17
UniRef50_A8SDR7 Putative uncharacterized protein n=1 Tax=Faecali...    90   6e-17
UniRef50_A8ZZ17 CRISPR-associated protein Cas5 family n=1 Tax=De...    90   6e-17
UniRef50_B4TTX2 CRISPR-associated protein Cas5 n=15 Tax=Enteroba...    89   1e-16
UniRef50_D0Y918 CRISPR-associated protein Cas5 family n=2 Tax=De...    89   1e-16
UniRef50_D2L2X8 CRISPR-associated protein Cas5 family n=1 Tax=De...    87   6e-16
UniRef50_Q0W584 Putative uncharacterized protein n=1 Tax=uncultu...    87   6e-16
UniRef50_D1CGD4 CRISPR-associated protein Cas5 family n=6 Tax=Ba...    85   2e-15
UniRef50_Q47PI7 CRISPR-associated protein, Cas5e family n=12 Tax...    84   3e-15
UniRef50_A7BA63 Putative uncharacterized protein n=1 Tax=Actinom...    83   7e-15
UniRef50_D1NTI1 CRISPR-associated protein Cas5 n=1 Tax=Bifidobac...    82   1e-14
UniRef50_C8XAY4 CRISPR-associated protein Cas5 family n=2 Tax=Ac...    82   1e-14
UniRef50_Q2JH27 CRISPR-associated protein, CT1976 n=6 Tax=Actino...    82   2e-14
UniRef50_C7LYW6 CRISPR-associated protein Cas5 family n=1 Tax=Ac...    82   2e-14
UniRef50_B0S4B6 Putative uncharacterized protein n=1 Tax=Finegol...    80   5e-14
UniRef50_B2GBJ9 Putative uncharacterized protein n=1 Tax=Lactoba...    80   7e-14
UniRef50_Q5YRB6 Putative uncharacterized protein n=1 Tax=Nocardi...    79   1e-13
UniRef50_B3E5U9 CRISPR-associated protein Cas5 family n=2 Tax=De...    79   1e-13
UniRef50_A3EQA4 CRISPR-ssociated protein, Cas5 n=3 Tax=Bacteria ...    79   1e-13
UniRef50_B0TDU1 Crispr-associated protein cas5 n=1 Tax=Heliobact...    78   2e-13
UniRef50_C9M9R7 CRISPR-associated protein Cas5, Ecoli subtype n=...    77   4e-13
UniRef50_A5GBK2 CRISPR-associated protein Cas5 family n=2 Tax=De...    77   6e-13
UniRef50_D1Y486 Crispr-associated protein Cas5 n=1 Tax=Pyramidob...    76   7e-13
UniRef50_D0WFC8 CRISPR-associated protein Cas5 n=1 Tax=Slackia e...    76   7e-13
UniRef50_B1VIY0 CRISPR-associated protein n=9 Tax=Actinomycetale...    76   8e-13
UniRef50_D2RB02 CRISPR system CASCADE complex protein CasD n=3 T...    76   8e-13
UniRef50_C9M2Y8 CRISPR-associated protein n=1 Tax=Lactobacillus ...    76   1e-12
UniRef50_UPI0001AF1D4C CRISPR-associated protein, CT1976 n=1 Tax...    74   5e-12
UniRef50_A8M404 CRISPR-associated protein Cas5 family n=1 Tax=Sa...    73   7e-12
UniRef50_B4UE71 CRISPR-associated protein Cas5 family n=2 Tax=An...    71   3e-11
UniRef50_D0MET6 CRISPR-associated protein Cas5 family n=1 Tax=Rh...    71   3e-11
UniRef50_Q0BSC7 Putative uncharacterized protein n=1 Tax=Granuli...    70   5e-11
UniRef50_B8GIV3 CRISPR-associated protein Cas5 family n=1 Tax=Me...    70   6e-11
UniRef50_A1ARH6 CRISPR-associated protein, Cas5e family n=2 Tax=...    69   1e-10
UniRef50_B5GY62 Crispr-associated protein (Fragment) n=1 Tax=Str...    69   1e-10
UniRef50_A9HLC6 CRISPR-associated protein Cas5 family n=11 Tax=A...    69   1e-10
UniRef50_B6B783 CRISPR-associated protein Cas5, Ecoli subtype n=...    69   2e-10
UniRef50_Q0AA33 CRISPR-associated protein Cas5 family n=2 Tax=Ga...    67   3e-10
UniRef50_C2KP44 Putative uncharacterized protein n=1 Tax=Mobilun...    67   5e-10
UniRef50_Q1J367 CRISPR-associated protein, CT1976 n=1 Tax=Deinoc...    67   5e-10
UniRef50_Q2FNU0 CRISPR-associated protein, CT1976 n=1 Tax=Methan...    67   6e-10
UniRef50_C2GEY8 CRISPR-associated protein n=1 Tax=Corynebacteriu...    65   2e-09
UniRef50_Q03C60 CRISPR-associated protein n=4 Tax=Lactobacillus ...    65   2e-09
UniRef50_UPI0001B51C2B CRISPR-associated Cas5 family protein n=1...    64   6e-09
UniRef50_B5F422 CRISPR-associated protein Cas5 n=59 Tax=Enteroba...    62   2e-08
UniRef50_B4S8P8 CRISPR-associated protein Cas5 family n=8 Tax=Ba...    60   4e-08
UniRef50_C5V9N1 CRISPR-associated protein Cas5 n=1 Tax=Corynebac...    60   4e-08
UniRef50_B8IZA7 CRISPR-associated protein Cas5 family n=1 Tax=De...    60   4e-08
UniRef50_B6IWM3 CRISPR-associated protein, CT1976 family n=1 Tax...    59   1e-07
UniRef50_B8IMR2 CRISPR-associated protein Cas5 family n=1 Tax=Me...    59   2e-07
UniRef50_Q2JWC5 CRISPR-associated protein Cas5, Ecoli subtype n=...    58   3e-07
UniRef50_D1CAJ0 CRISPR-associated protein Cas5 family n=1 Tax=Sp...    57   4e-07
UniRef50_B8FDI0 CRISPR-associated protein Cas5 family n=3 Tax=Ba...    55   2e-06
UniRef50_B8HWH8 CRISPR-associated protein Cas5 family n=1 Tax=Cy...    54   3e-06
UniRef50_B6XT64 Putative uncharacterized protein n=2 Tax=Bifidob...    50   6e-05
UniRef50_Q2RXJ5 CRISPR-associated protein, Cas5e family n=5 Tax=...    50   7e-05
UniRef50_Q6NEQ9 Putative uncharacterized protein n=1 Tax=Coryneb...    49   1e-04
UniRef50_C0W6U0 CRISPR-associated Cas5 family protein n=1 Tax=Ac...    49   2e-04
UniRef50_B8IJS9 CRISPR-associated protein Cas5 family n=1 Tax=Me...    40   0.046

>UniRef50_Q46898 Uncharacterized protein ygcI n=13 Tax=Proteobacteria
           RepID=YGCI_ECOLI
          Length = 224

 Score =  462 bits (1190), Expect = e-129,   Method: Compositional matrix adjust.
 Identities = 224/224 (100%), Positives = 224/224 (100%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES
Sbjct: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL
Sbjct: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180
           WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD
Sbjct: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180

Query: 181 IYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVSQ 224
           IYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVSQ
Sbjct: 181 IYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVSQ 224


>UniRef50_C5SD48 CRISPR-associated protein Cas5 family n=1 Tax=Allochromatium
           vinosum DSM 180 RepID=C5SD48_CHRVI
          Length = 227

 Score =  155 bits (392), Expect = 8e-37,   Method: Compositional matrix adjust.
 Identities = 109/225 (48%), Positives = 137/225 (60%), Gaps = 15/225 (6%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M SYLILRL GPMQAWG  TFE  RP+  FPTRSGLLGLLGACLG+ R DT SL AL+ES
Sbjct: 1   MPSYLILRLDGPMQAWGTHTFEDYRPSNPFPTRSGLLGLLGACLGLDRSDTPSLDALAES 60

Query: 61  VQFAVRCD--------ELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLC 112
           V F VR D        + ++  R    T L DYHTVL AR+   G  +   IQ+ REYL 
Sbjct: 61  VAFTVRLDTGAPRPGVDRLMPKRH---TKLSDYHTVLDARK-VDGSTNKFPIQSHREYLF 116

Query: 113 DASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLF--LGTCQASDPQKA 170
           DA+F VA+   P A+  ++ + +++ +PR+TP LGRRSCPL  PL       +A D + A
Sbjct: 117 DAAFAVAIGSRPDASFSLARIAESLRQPRFTPVLGRRSCPLGRPLLERPDCIEADDAKAA 176

Query: 171 LLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYV 215
           L  + P GG IYSE+ +      +  RD P     RQFA+R  Y+
Sbjct: 177 LAQFPPHGGLIYSEDELVSDQPTWI-RDVPRYGRHRQFATRRLYL 220


>UniRef50_A1SV73 CRISPR-associated protein, Cas5e family n=2 Tax=Gammaproteobacteria
           RepID=A1SV73_PSYIN
          Length = 217

 Score =  119 bits (298), Expect = 7e-26,   Method: Compositional matrix adjust.
 Identities = 81/216 (37%), Positives = 116/216 (53%), Gaps = 25/216 (11%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           LIL+  G M A+G  TF+  R    FPTRS ++G+LGA +GI R++ + L ALSE ++ A
Sbjct: 4   LILKTEG-MSAYGLQTFDVHRRANHFPTRSAIMGILGAAMGITRENFNELYALSEQLKIA 62

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAR----EDYRGLKSHETIQTWREYLCDASFTVAL 120
           V+ +        +S   + DYHTV   R    +  +G+K      T+REY CD+  T A+
Sbjct: 63  VQVN--------LSGEKMVDYHTVQHFRSPQGKIQKGVKP-----TYREYWCDSEHTFAI 109

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180
               H   VI +L  +V  P +T + GR+SCPLT PLF       +P  AL N+    G 
Sbjct: 110 SAAEH---VIEKLVNSVKFPEFTLFQGRKSCPLTRPLFEAVTDDDNPANALKNHGE-QGQ 165

Query: 181 IYSEESVTGHHLKFTARDEPMIT-LPRQFASREWYV 215
           I+S+ S          RD  +IT +PR++A R  YV
Sbjct: 166 IFSDISGDNQLAIVQVRD--LITAIPRKYAMRTVYV 199


>UniRef50_A6W168 CRISPR-associated protein Cas5 family n=6 Tax=Gammaproteobacteria
           RepID=A6W168_MARMS
          Length = 258

 Score =  114 bits (285), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 70/165 (42%), Positives = 93/165 (56%), Gaps = 23/165 (13%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M+ YL+ RL GPM +WGQP   G R T   PTRS +LGLLGA LGI+RDD   L AL  S
Sbjct: 1   MKDYLVFRLYGPMASWGQPAVGGDRATAIAPTRSAILGLLGAALGIKRDDAQQLDALHSS 60

Query: 61  VQFAVRCDELILDDRRVSVTG-LRDYHTV-LGARED---YRGLKSH---------ETIQT 106
           VQ A          ++V+ T  LRDYHT  + +R +   YR  K+           TI +
Sbjct: 61  VQMAT---------KQVTPTSLLRDYHTSQVPSRNNKYVYRTRKNELLDEHKEKLNTILS 111

Query: 107 WREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSC 151
            R+Y CD  + VA+ LT  +   +  L++A++KP Y   LGR+SC
Sbjct: 112 TRDYRCDGIWIVAVSLTQESLFSLERLKQALIKPVYVLSLGRKSC 156


>UniRef50_Q1R114 CRISPR-associated protein, CT1976 n=1 Tax=Chromohalobacter
           salexigens DSM 3043 RepID=Q1R114_CHRSD
          Length = 260

 Score =  112 bits (279), Expect = 1e-23,   Method: Compositional matrix adjust.
 Identities = 68/183 (37%), Positives = 96/183 (52%), Gaps = 20/183 (10%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M  +L+ RL  PM +WG+      RPT  +P R  +LGL+GA LGI+RDD      L +S
Sbjct: 1   MTGHLVFRLYAPMASWGEAAVGEARPTATYPGRGAILGLIGAALGIRRDDDEGQLRLRQS 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVL----GAREDYRGLKSH--------ETIQTWR 108
           +  AV+        +R     LRDYHTV      ++ +YR  +           TI + R
Sbjct: 61  LGIAVK--------QRSPGWLLRDYHTVQVPPSQSKVNYRSRREELSVPKDALNTILSSR 112

Query: 109 EYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQ 168
           +Y CD  + VAL L P A   + EL+ A+ +PR+T YLGR++CPL  PL     +A   +
Sbjct: 113 DYRCDGLWVVALRLMPDAVWTLDELKSALERPRFTLYLGRKACPLAAPLTPAIVEADHWR 172

Query: 169 KAL 171
            AL
Sbjct: 173 GAL 175


>UniRef50_Q314I4 CRISPR-associated protein, CT1976 n=1 Tax=Desulfovibrio
           desulfuricans subsp. desulfuricans str. G20
           RepID=Q314I4_DESDG
          Length = 245

 Score =  111 bits (277), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 84/239 (35%), Positives = 114/239 (47%), Gaps = 19/239 (7%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M  YL  ++ GP+QA+G       RPT   PTRS +LG+L A +GI+RD+ + L  L + 
Sbjct: 1   MAQYLTFQIYGPLQAYGTVAVGEIRPTSTMPTRSAVLGILAAAIGIRRDEETRLAELRDG 60

Query: 61  VQFAVRCD---ELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFT 117
            + AVR D   +++LD   +   G R     L  R D   L    TI + REYL DA FT
Sbjct: 61  YRVAVREDAPGKVMLDYHTIQTPGARGKRQ-LHCRRDELLLTEPNTILSRREYLMDALFT 119

Query: 118 VALWLTPHAT-MVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEP 176
           V LW   H     + E+ +A+  PR+T  LGR+SCP   P        + PQ+A+  Y  
Sbjct: 120 VCLWQANHTVPYSLQEIARALRSPRWTIGLGRKSCPPALPFAPKITDHTTPQEAVAAYPA 179

Query: 177 ---VGGDIYSEE------SVTGHH--LKFTARDEPMITLPRQFAS---REWYVIKGGMD 221
              V   + S +         G H   + T RD P+    RQFA    RE  V K   D
Sbjct: 180 DKLVSAGLRSPQVMRMLLDTEGPHTDTETTVRDVPLHHGRRQFAERKVRELLVRKAATD 238


>UniRef50_Q04QB7 Putative uncharacterized protein n=2 Tax=Leptospira borgpetersenii
           serovar Hardjo-bovis RepID=Q04QB7_LEPBJ
          Length = 247

 Score =  100 bits (249), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 58/167 (34%), Positives = 85/167 (50%), Gaps = 18/167 (10%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M+ YL+ RL GP+ +WG       RP+  FPT+S ++GL+ A  G  R +   +  L +S
Sbjct: 1   MKDYLVFRLYGPLVSWGNIAVGEYRPSDSFPTKSAIIGLISASFGFDRSEDGKISELVKS 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSH----------ETIQTWREY 110
           V FA +     L+   +    LRDYHT+       R L +           ETI + R+Y
Sbjct: 61  VFFATKT----LNPGNL----LRDYHTIQSPGNVKRSLLTRKDELLDSEYVETILSSRDY 112

Query: 111 LCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPL 157
             DA + VAL     A   + E+  A+L P +TPYLGR+SC +  P+
Sbjct: 113 RVDAVYDVALSEKKRAPYSLKEIRNALLSPIHTPYLGRKSCSIALPM 159


>UniRef50_C7MTB0 CRISPR-associated protein Cas5 n=1 Tax=Saccharomonospora viridis
           DSM 43017 RepID=C7MTB0_SACVD
          Length = 255

 Score =  100 bits (249), Expect = 4e-20,   Method: Compositional matrix adjust.
 Identities = 73/201 (36%), Positives = 101/201 (50%), Gaps = 24/201 (11%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
           S L+LRLAGP+Q+WG+ +    R T  FPT SGLLGLL   +G +R +  SL+ L+ ++ 
Sbjct: 2   SGLLLRLAGPLQSWGERSTFDVRDTAGFPTHSGLLGLLACVMGRRRGE--SLEDLA-ALT 58

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGA--------REDYRGLKSHE-TIQTWREYLCD 113
           F +R D           T + DY T  GA          D +G  + + T+QTWREYL D
Sbjct: 59  FTIRVDR--------PGTRIIDYQTAGGALPPSMKVPTADGKGRPAGKGTVQTWREYLAD 110

Query: 114 ASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLN 173
           A F VA+      + V+ ++  A+  P + PYLGRRSCP   PL L      DP   L  
Sbjct: 111 AVFVVAVQ---GPSEVLDQVRHALRYPHWQPYLGRRSCPPDQPLLL-DVPVEDPVAELCT 166

Query: 174 YEPVGGDIYSEESVTGHHLKF 194
             P+   +  +E        F
Sbjct: 167 RVPLARRVGKDEETVPVDFIF 187


>UniRef50_B7KJ26 CRISPR-associated protein Cas5 family n=1 Tax=Cyanothece sp. PCC
           7424 RepID=B7KJ26_CYAP7
          Length = 215

 Score = 97.4 bits (241), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 56/160 (35%), Positives = 96/160 (60%), Gaps = 14/160 (8%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M   L+LRLAGP+Q+WG+ +    R T   PT+SG++GL+ A +GI RD+   L  L++ 
Sbjct: 1   MMKTLLLRLAGPLQSWGRGSRFDFRDTDTIPTKSGVIGLVAAAMGINRDNQVELAKLAQ- 59

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHET-IQTWREYLCDASFTVA 119
               +R    +  + ++ V    DYHTV+G    +   K H+  IQ++R+YLC+A F V 
Sbjct: 60  ----LRMGVCVEKEGKLVV----DYHTVIGTI--HADGKPHKAPIQSYRQYLCNAEFLVG 109

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFL 159
           L  + +   +++E+E  +  P++  +LGR++CP + P+F+
Sbjct: 110 LESSEYH--LLNEIEHYLCFPKWELFLGRKACPPSKPIFV 147


>UniRef50_A8LYZ7 CRISPR-associated protein Cas5 family n=2 Tax=Actinomycetales
           RepID=A8LYZ7_SALAI
          Length = 257

 Score = 97.1 bits (240), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 84/242 (34%), Positives = 114/242 (47%), Gaps = 49/242 (20%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           L+LRLAGPMQ+WG  +    R TG  PTRS ++G++ A  G  R +   L  L+  VQF 
Sbjct: 4   LLLRLAGPMQSWGDHSTFSVRDTGTVPTRSAMIGIIAAAQGRHRGE--PLGDLAP-VQFT 60

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHE---------TIQTWREYLCDAS 115
           VR D           T + D+HTV G     R + + E         TI + R YL DA 
Sbjct: 61  VRVDR--------PGTVMSDFHTVGGGAPPERTVPTAEGKRRTAGAGTIVSRRFYLADAV 112

Query: 116 FTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKAL---- 171
           FTVA+        ++ ++  A+  P + PYLGRRSCP+ HP FL +    DP   L    
Sbjct: 113 FTVAVT---GPDDLVGQIHTALNNPVWGPYLGRRSCPVAHP-FLMSGPIPDPVGRLEHLP 168

Query: 172 LNYEPVGGDIYSEESV-----------TGHHLKFTARDEPMITLP-------RQFASREW 213
           LN     GD   EE+V            G   + T  D PM  +P       R++ +R+ 
Sbjct: 169 LNRRRPPGD---EETVRVDFVTGAPHGDGSISRMTLNDVPMEPVPGSPDPRRRRYLTRQV 225

Query: 214 YV 215
           YV
Sbjct: 226 YV 227


>UniRef50_C7MQD6 CRISPR-associated protein Cas5 n=1 Tax=Saccharomonospora viridis
           DSM 43017 RepID=C7MQD6_SACVD
          Length = 236

 Score = 94.7 bits (234), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 75/217 (34%), Positives = 108/217 (49%), Gaps = 22/217 (10%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           L+L L GPMQAWG  +    R T  +PTRSG++G++ A LG Q  D  SL  LS  ++F 
Sbjct: 4   LVLHLDGPMQAWGHASQWDHRDTLDYPTRSGVIGMIAAALGKQWGD--SLDDLS-PLRFT 60

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGARE----DYRGLKSHETIQTWREYLCDASFTVAL 120
           +R D      RR+      DYHT  G  E      +G      + + R Y+ DA++TVA+
Sbjct: 61  IRIDR---PGRRIV-----DYHTAGGGYEVGIARVKGGNRAHAVLSDRFYMSDAAYTVAI 112

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNY--EPVG 178
                   ++  ++ A+  P + P+LGRRSCP   P  LG     DP + L  +  +P  
Sbjct: 113 ---TGPDTLLYRVDDALRAPVFGPFLGRRSCPPAGPWHLG-LHDGDPLRTLPLHRDKPRD 168

Query: 179 GDIYSEESVTGHHLKF-TARDEPMITLPRQFASREWY 214
           GD  + E V+ H     T R +  +T P +F  R  Y
Sbjct: 169 GDTVAVEFVSDHETHGPTDRVDTTLTDPHEFGPRRSY 205


>UniRef50_Q1EQS9 CRISPR-associated protein n=3 Tax=Streptomyces RepID=Q1EQS9_STRKN
          Length = 280

 Score = 94.7 bits (234), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 63/168 (37%), Positives = 88/168 (52%), Gaps = 20/168 (11%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           L+LRL+GP+Q+WG+ +    R T RFPTRSG++G+L A LG +R          E V   
Sbjct: 14  LLLRLSGPLQSWGERSHFNERDTARFPTRSGIIGMLAAALGRRR---------GEPVDDL 64

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHE---------TIQTWREYLCDAS 115
            R    +  DR   +  LRD HTV G       + + E         T+ T R YL DA+
Sbjct: 65  ARLSLTVRTDRPGIL--LRDLHTVGGGLPAKATVTTAEGKKRPGTTGTLLTHRTYLADAA 122

Query: 116 FTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQ 163
           FT+AL  TP    ++ +  +A+  P +  +LGRRSCP   PL LG  +
Sbjct: 123 FTIALTSTPDDRPLLDQAAQALNTPCWPLFLGRRSCPPEGPLLLGASE 170


>UniRef50_Q2RY19 CRISPR-associated protein, Cas5e family n=1 Tax=Rhodospirillum
           rubrum ATCC 11170 RepID=Q2RY19_RHORT
          Length = 261

 Score = 94.0 bits (232), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 74/234 (31%), Positives = 102/234 (43%), Gaps = 32/234 (13%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           +R +L+ RL GPM AWG       R T   P +S +LGLL A LGI R D ++ +AL   
Sbjct: 3   VRDFLVFRLVGPMAAWGDIAVGERRGTWDVPAKSAILGLLAAGLGIDRADRTAHEALDRG 62

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTV----------LGAREDYRGLKSHETIQTWREY 110
           + FAVR D             LRDYHT              R D        T+ + R Y
Sbjct: 63  LGFAVRQDR--------PGRLLRDYHTAQAPKARKNARWSTRRDELNDDDLNTVLSDRLY 114

Query: 111 LCDASFTVALWLTPHATM-VISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQK 169
             +A  T A+W         + +L +A+L+PR+TPYLGR++CPL  P      QA     
Sbjct: 115 RTNAIATPAIWRRQGTEGPTLDQLTQALLRPRFTPYLGRKACPLGWPPRPRLLQADGLLA 174

Query: 170 ALLNYEPVGGDIYSE--ESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMD 221
           A   Y+    D   +  ++  G     T R  P+           W+ I  G+D
Sbjct: 175 AFDAYDSAEWDAARQFHKAYPGGWPGDTDRPTPV-----------WFEIAAGLD 217


>UniRef50_C2BET8 CRISPR-associated protein n=2 Tax=Firmicutes RepID=C2BET8_9FIRM
          Length = 244

 Score = 93.2 bits (230), Expect = 6e-18,   Method: Compositional matrix adjust.
 Identities = 59/183 (32%), Positives = 99/183 (54%), Gaps = 17/183 (9%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           ++L+L GPMQ+WG  +   TR +  +P++SG++G++ A  G +RD+   +Q L++ + FA
Sbjct: 7   ILLKLTGPMQSWGTSSRFETRTSDYYPSKSGVIGIIAASFGYERDEDEKIQKLND-LDFA 65

Query: 65  VRCD-ELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLT 123
           VR D E +L          +DYH    AR+     +   T  T R Y+ DA F VA  ++
Sbjct: 66  VRVDQEGVLK---------KDYHI---ARKVKPNGELERTYVTNRYYMEDAVFVVA--IS 111

Query: 124 PHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDIYS 183
                 + E+ + +  P + P++GRRSCPL     LGT +   P +AL N +    D + 
Sbjct: 112 HEDDKWMEEILQGLKYPYFQPFMGRRSCPLPARFILGTNEEG-PIEALENLDWQAADWFK 170

Query: 184 EES 186
           +++
Sbjct: 171 KKN 173


>UniRef50_A5UR14 CRISPR-associated protein, Cas5e family n=1 Tax=Roseiflexus sp.
           RS-1 RepID=A5UR14_ROSS1
          Length = 262

 Score = 91.7 bits (226), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 71/202 (35%), Positives = 96/202 (47%), Gaps = 45/202 (22%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           L LRL GP+Q+WG     G R T   PT+SG++GLLG  LG++RDD + L+ LS++++  
Sbjct: 4   LFLRLEGPLQSWGLRARWGERDTTDAPTKSGVIGLLGCALGLRRDD-ARLRDLSDNLRMG 62

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAR--------------EDYRG------------- 97
           VR D        +    +RDYHT  G R              E Y G             
Sbjct: 63  VRVD--------LPGILMRDYHTTGGGRYSTIASTGGPRYHDEPYIGGVLSAEVTKGRIK 114

Query: 98  ------LKSHETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSC 151
                     ET  + R YL DASF VAL  +P     I EL  A+  P +  +LGR++C
Sbjct: 115 VKINQKTGEPETDVSERYYLADASFLVALQGSPD---YIGELATAIQSPVWPLFLGRKAC 171

Query: 152 PLTHPLFLGTCQASDPQKALLN 173
             + P+F GT Q    + AL N
Sbjct: 172 VPSTPIFAGTGQFDILEDALKN 193


>UniRef50_Q12YA8 CRISPR-associated protein, CT1976-like n=1 Tax=Methanococcoides
           burtonii DSM 6242 RepID=Q12YA8_METBU
          Length = 244

 Score = 91.7 bits (226), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 63/194 (32%), Positives = 95/194 (48%), Gaps = 28/194 (14%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M+ YLI RL GPM +WG       RPT   P++S + GL+ A LGI+RD+      LS +
Sbjct: 1   MKEYLIFRLYGPMASWGDIAVGQHRPTYDHPSKSAIFGLIAAALGIRRDEEERHLELSNA 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHT-------------VLGAREDYRGLKSHE--TIQ 105
             +      LI    ++    LRDYHT                 R+D   +   E  T+ 
Sbjct: 61  YSYGT----LINSAGKL----LRDYHTSQVPSAGTGRNRKTFATRKDELAVPKEELNTVL 112

Query: 106 TWREYLCDASFTVALWL---TPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTC 162
           + R+Y CD  +TV L     TP  ++ +  L  ++ +P +  YLGR+SCPL  P+     
Sbjct: 113 STRDYYCDGVYTVILSCKTDTPPYSLEL--LGNSLKEPSFCLYLGRKSCPLALPINPKIV 170

Query: 163 QASDPQKALLNYEP 176
            AS+ ++AL + +P
Sbjct: 171 SASNIKEALQSVDP 184


>UniRef50_D1A6Q5 CRISPR-associated protein Cas5 family n=2 Tax=Actinomycetales
           RepID=D1A6Q5_THECD
          Length = 273

 Score = 90.9 bits (224), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 67/179 (37%), Positives = 94/179 (52%), Gaps = 25/179 (13%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQR-DDTSSLQALSESVQF 63
           L+L L+GP+Q+WG+ +    R T   PTRSGL+G++ A  G +R +  + L+AL    +F
Sbjct: 9   LLLHLSGPLQSWGERSRFNQRDTATAPTRSGLIGMIAAAFGRRRTEPVTDLRAL----RF 64

Query: 64  AVRCDELILDDRRVSVTGLRDYHTVLGA---------REDYRGLKSHETIQTWREYLCDA 114
            VR D           T LRD+HTV G           E  R      T+ + R YL DA
Sbjct: 65  TVRIDR--------PGTLLRDFHTVGGGMPRDLTVITAEGKRRAADTATVTSDRYYLQDA 116

Query: 115 SFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLN 173
           +FTVA  +T     ++    +A+  PR+  YLGRRSCP   PL L T   +DP  AL++
Sbjct: 117 AFTVA--VTADDPALLDRCAQALRAPRWPLYLGRRSCPPNAPLLL-TVLRTDPVTALID 172


>UniRef50_A8SDR7 Putative uncharacterized protein n=1 Tax=Faecalibacterium
           prausnitzii M21/2 RepID=A8SDR7_9FIRM
          Length = 220

 Score = 89.7 bits (221), Expect = 6e-17,   Method: Compositional matrix adjust.
 Identities = 68/172 (39%), Positives = 95/172 (55%), Gaps = 20/172 (11%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           L+LRLA P+QAWG  +   TR TGR PT+SG++GLL A LG++RD++ +L  L+  ++F 
Sbjct: 4   LLLRLAAPLQAWGADSKFETRKTGREPTKSGVIGLLAAALGLRRDESEALTRLT-GLRFG 62

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTP 124
           VR +             L DYHT     E         +  T+R YL DA F   +  T 
Sbjct: 63  VRVER--------EGQLLVDYHTAKTQDE-------KTSYVTYRHYLQDAVFLAGIEST- 106

Query: 125 HATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEP 176
             T ++ +L++A+L P +  YLGRR CP T PL LG C  S   + +L  EP
Sbjct: 107 -DTALLQQLQQALLHPAFPLYLGRRCCPPTLPLCLGVCPGS--LQEVLQAEP 155


>UniRef50_A8ZZ17 CRISPR-associated protein Cas5 family n=1 Tax=Desulfococcus
           oleovorans Hxd3 RepID=A8ZZ17_DESOH
          Length = 259

 Score = 89.7 bits (221), Expect = 6e-17,   Method: Compositional matrix adjust.
 Identities = 60/166 (36%), Positives = 83/166 (50%), Gaps = 20/166 (12%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
           YL+ RL GPM +WG+     TR T  +P RS ++GL+ A LGI+R +T + QAL +    
Sbjct: 3   YLLFRLYGPMASWGEIAVGETRHTANYPGRSAIIGLMAAALGIKRSETENQQALDQGCLI 62

Query: 64  AVRCDELILDDRRVSVTGLRDYHT----------VLGARED--YRGLKSHETIQTWREYL 111
           AV          R   + LRDYHT          V   R D    G     TI + REY 
Sbjct: 63  AVEA--------RSHGSLLRDYHTTQVPDSVGGFVYRTRRDELIIGKPRLGTILSSREYR 114

Query: 112 CDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPL 157
            DA    A+ + P A   +  ++  + +PR   YLGR+SCPL+ P+
Sbjct: 115 QDALAVSAVRVLPGARYELQTIKTHLEQPRLHVYLGRKSCPLSAPM 160


>UniRef50_B4TTX2 CRISPR-associated protein Cas5 n=15 Tax=Enterobacteriaceae
           RepID=B4TTX2_SALSV
          Length = 241

 Score = 89.0 bits (219), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 67/169 (39%), Positives = 89/169 (52%), Gaps = 19/169 (11%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M+ YL+ +L  P+ +WG+      R +   PTRS LLGLL A LGI+RD+ + L   +  
Sbjct: 1   MKEYLVFQLYAPLASWGEEASGEIRHSATVPTRSALLGLLAAALGIRRDEEARLNNFNRH 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGARED--YRGLKSHE----------TIQTWR 108
              AV    L   DR      LRDYHTV   RE+  YR     +          T+ + R
Sbjct: 61  YHLAVHA--LASQDR-----WLRDYHTVSAPRENKKYRYYTRRDELTLAPDEVGTLISQR 113

Query: 109 EYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPL 157
           EY CD  + VA+  TP A   +SEL +A+L P +  YLGR+SCPL  PL
Sbjct: 114 EYRCDGYWHVAISATPDAPHSLSELREALLTPHFPLYLGRKSCPLALPL 162


>UniRef50_D0Y918 CRISPR-associated protein Cas5 family n=2 Tax=Dehalococcoides
           RepID=D0Y918_9CHLR
          Length = 205

 Score = 88.6 bits (218), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 57/153 (37%), Positives = 89/153 (58%), Gaps = 17/153 (11%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           L++RL GPMQ+WG  +    R T   PTRSG++GL+ A +GI RD+     A  + ++  
Sbjct: 7   LLMRLEGPMQSWGYRSRFDCRDTALEPTRSGVIGLICAAMGIARDEDI---ARFDGIRMG 63

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGA-REDYRGLKSHETIQTWREYLCDASFTVALWLT 123
           VR D     D +V     +DYHT L   + D  G    +T+ ++R+YL DASFTV L  +
Sbjct: 64  VRVDR----DGKVE----QDYHTALDVIKADGSG---KDTVVSYRDYLTDASFTVGLESS 112

Query: 124 PHATMVISELEKAVLKPRYTPYLGRRSCPLTHP 156
                ++ ++ KA++ P++  +LGR++ PLT P
Sbjct: 113 DRN--LLEKIAKALVSPQWVLFLGRKAFPLTKP 143


>UniRef50_D2L2X8 CRISPR-associated protein Cas5 family n=1 Tax=Desulfovibrio sp.
           FW1012B RepID=D2L2X8_9DELT
          Length = 266

 Score = 86.7 bits (213), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 67/197 (34%), Positives = 91/197 (46%), Gaps = 33/197 (16%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M  YLI +L G + A+G       R +   PTRS + GLL ACLGI+R + + L ALS  
Sbjct: 1   MARYLIFQLYGMLAAYGLVAVGEVRLSAGHPTRSAVFGLLAACLGIRRHEEARLAALSGG 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL---KSHE------------TIQ 105
              AVR D           T L DYHT+    E  + +   ++ E            T+ 
Sbjct: 61  YALAVRVD--------APGTSLLDYHTIQTPPEKSKRIYRTRADELGGLLGIDEPPYTVL 112

Query: 106 TWREYLCDASFTVALWLTPHAT--------MVISELEKAVLKPRYTPYLGRRSCPLTHPL 157
           + R YLCDA FT    LTP A           +  L +A+ +P  TPYLGR+SCP + P 
Sbjct: 113 SRRGYLCDAHFTA--CLTPAAAPPTDATPPHTLEALAEALRRPVLTPYLGRKSCPPSLPF 170

Query: 158 FLGTCQASDPQKALLNY 174
                +    + AL +Y
Sbjct: 171 HPRLGEYDSLEAALADY 187


>UniRef50_Q0W584 Putative uncharacterized protein n=1 Tax=uncultured methanogenic
           archaeon RC-I RepID=Q0W584_UNCMA
          Length = 227

 Score = 86.7 bits (213), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 55/150 (36%), Positives = 74/150 (49%), Gaps = 15/150 (10%)

Query: 11  GPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDEL 70
           GPMQ+WG       R TG  PT+SG++GLLG  LG  R D      L   ++  +     
Sbjct: 13  GPMQSWGLKARWDIRDTGDEPTKSGIIGLLGCALGYARKDPRLTDELDSQLRIGI----- 67

Query: 71  ILDDRRVSVTG--LRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPHATM 128
                RV   G   RDYHTV G      G     TI ++R+YL DA+F V L        
Sbjct: 68  -----RVECPGEIARDYHTVSGELRTAEGKLRETTIVSFRDYLQDAAFLVVL---EGPGE 119

Query: 129 VISELEKAVLKPRYTPYLGRRSCPLTHPLF 158
           +++ +  A+  P +  YLGR+SCP T P+F
Sbjct: 120 LLTRISNALKDPVWPIYLGRKSCPPTRPVF 149


>UniRef50_D1CGD4 CRISPR-associated protein Cas5 family n=6 Tax=Bacteria
           RepID=D1CGD4_THET1
          Length = 230

 Score = 84.7 bits (208), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 68/207 (32%), Positives = 105/207 (50%), Gaps = 34/207 (16%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           L++RL+GPMQ+WG  +    R TGR P++SG++GL+ A LG  R  T+ +  L   ++  
Sbjct: 4   LLMRLSGPMQSWGTQSRFTVRDTGREPSKSGVIGLICAALG--RPRTAPVDDLVR-LRMG 60

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYR-GLKS----HETIQTWREYLCDASFTVA 119
           VR D       R  +  +RDYHT  GA    R G+ +       +Q+ R YL DASF VA
Sbjct: 61  VRVD-------REGIV-MRDYHTAGGAPAGERYGVATVTGDQRPVQSSRYYLADASFLVA 112

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGT-------CQASDPQKALL 172
           L        ++ ++++A+  PR+  +LGR+SC  + P+ L          +  D + AL+
Sbjct: 113 LEGGEEDRPLLEQIDEALRAPRWQLFLGRKSCVPSEPIHLPKEPPLGPPIREEDLRTALI 172

Query: 173 NYE-PVGGDIYSEESVTGHHLKFTARD 198
           +Y  P G           H L+F   D
Sbjct: 173 SYPWPEG----------AHRLRFVFED 189


>UniRef50_Q47PI7 CRISPR-associated protein, Cas5e family n=12 Tax=Actinomycetales
           RepID=Q47PI7_THEFY
          Length = 245

 Score = 84.0 bits (206), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 66/173 (38%), Positives = 89/173 (51%), Gaps = 25/173 (14%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQR-DDTSSLQALSESVQF 63
           L L LAGP+QAWG  +    R T   PT+SG+LGLL A  G +R DD S L AL    +F
Sbjct: 4   LTLLLAGPLQAWGAASRFTRRTTEHAPTKSGVLGLLAAAQGRERTDDLSDLAAL----RF 59

Query: 64  AVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQ-TWREYLCDASFTVALWL 122
            VR D+          T +RD+ T +        L + +++  + R YL DA F  A+  
Sbjct: 60  GVRVDQ--------RGTRIRDFQTAI-------HLDTGKSMPVSERFYLADAVFVAAVE- 103

Query: 123 TPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYE 175
                 +I  L +AV  P Y PYLGRRSCP + P+ LG   +  P + +L  E
Sbjct: 104 --GEDTLIDTLHQAVQHPVYLPYLGRRSCPPSRPINLG-VHSGKPLEQVLAEE 153


>UniRef50_A7BA63 Putative uncharacterized protein n=1 Tax=Actinomyces odontolyticus
           ATCC 17982 RepID=A7BA63_9ACTO
          Length = 242

 Score = 82.8 bits (203), Expect = 7e-15,   Method: Compositional matrix adjust.
 Identities = 65/165 (39%), Positives = 86/165 (52%), Gaps = 22/165 (13%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M + L+LRLAGPMQ+WG  +    R T  FPT+S L+GLLGA  G +R D   ++ L+E 
Sbjct: 1   MSAVLVLRLAGPMQSWGADSRFTRRSTEAFPTKSALVGLLGAAQGRRRSD--PIEDLAE- 57

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           +  AVR D+            L D+HT    R D     SH      R Y  DA+F  A 
Sbjct: 58  LSVAVRVDQ--------PGQLLHDFHT--AHRGDTSMPLSH------RFYRADAAFG-AF 100

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQAS 165
              P    +I  L +A+++P +  YLGRRSCP T PL L   + S
Sbjct: 101 IEGPDD--MIDALAQAIVRPVFPLYLGRRSCPPTLPLRLAVREGS 143


>UniRef50_D1NTI1 CRISPR-associated protein Cas5 n=1 Tax=Bifidobacterium gallicum DSM
           20093 RepID=D1NTI1_9BIFI
          Length = 250

 Score = 82.4 bits (202), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 62/174 (35%), Positives = 92/174 (52%), Gaps = 15/174 (8%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
           S LILRLAGPMQ+WG  +    R T   PT+S ++GLL +  G +R+D  S++ L   ++
Sbjct: 2   SVLILRLAGPMQSWGDSSRFNRRETRTEPTKSAVIGLLASAQGRRRED--SIEDLL-GLR 58

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWL 122
           F VR D+      R+    +RD+ T         G  S     T R YL DA F VA+  
Sbjct: 59  FGVRSDQ----PGRI----MRDFQTEKSIARKKSGEFSLTMPLTHRYYLADAKFLVAI-- 108

Query: 123 TPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEP 176
                 ++  L+ A+  P++  +LGRRSCP   P+ LG    ++ ++A L+ EP
Sbjct: 109 -EGERSLLESLDAALRNPQWPLFLGRRSCPPASPVSLGVKDYANVEEA-LDKEP 160


>UniRef50_C8XAY4 CRISPR-associated protein Cas5 family n=2 Tax=Actinomycetales
           RepID=C8XAY4_NAKMY
          Length = 252

 Score = 82.4 bits (202), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 71/210 (33%), Positives = 98/210 (46%), Gaps = 22/210 (10%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
           S L+LRL GPMQ+WG+ +    R T   P++S ++GLL A LG +R D  +++ L+  + 
Sbjct: 2   SVLVLRLTGPMQSWGERSRYARRETAAEPSKSAIVGLLAAALGRRRTD--AIEDLAGLI- 58

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQ-TWREYLCDASFTVALW 121
           F VR D+          T LRD+ T        R L    T+  + R YL DA F  A+ 
Sbjct: 59  FGVRVDQ--------PGTLLRDFQTA-------RSLDGARTMPLSERYYLSDARFLAAVE 103

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
             P +  +I+ L  A+  P +  YLGRRSCP + P+    C  S P  A L  EP     
Sbjct: 104 -GPES--LIAGLAGALRDPTFPLYLGRRSCPPSEPIAQQDCIRSGPLLAALFDEPWHATK 160

Query: 182 YSEESVTGHHLKFTARDEPMITLPRQFASR 211
                V        A D     +P Q A R
Sbjct: 161 SYRRRVADPARLSIAVDAAATEVPAQLAER 190


>UniRef50_Q2JH27 CRISPR-associated protein, CT1976 n=6 Tax=Actinomycetales
           RepID=Q2JH27_FRASC
          Length = 276

 Score = 82.0 bits (201), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 69/187 (36%), Positives = 89/187 (47%), Gaps = 37/187 (19%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
           R  L+LRLAGP+Q+WG  +    R T   PT+SG++GLL A  G +R  T  ++ L  S+
Sbjct: 7   RHCLVLRLAGPLQSWGSRSMFNRRDTLTEPTKSGIIGLLAAAQGRRR--TDPIEDLL-SL 63

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL-----------------KSHETI 104
              +R D+          T LRDYHTV     DYRG                   +  T 
Sbjct: 64  TLGIRTDQ--------PGTLLRDYHTV----SDYRGRPLPSAAVSAKGLQKPTSPAKHTH 111

Query: 105 QTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQA 164
            T R YL DA F  AL        V++ L  A+  P +   LGRR+CP THPL L     
Sbjct: 112 VTERFYLQDAVFVAALAA---PEPVLTTLADALRTPAFPLALGRRACPPTHPLLL--VPD 166

Query: 165 SDPQKAL 171
           S+P  AL
Sbjct: 167 SEPDAAL 173


>UniRef50_C7LYW6 CRISPR-associated protein Cas5 family n=1 Tax=Acidimicrobium
           ferrooxidans DSM 10331 RepID=C7LYW6_ACIFD
          Length = 253

 Score = 81.6 bits (200), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 67/176 (38%), Positives = 86/176 (48%), Gaps = 31/176 (17%)

Query: 3   SYLILRLAGPMQAWGQPT-FEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
           S L LRL GP+QAWG     +  R T RFPT+SG++GLL A LG  R  +++L  L  ++
Sbjct: 2   SVLALRLGGPLQAWGSSQRLDHYRRTERFPTKSGVIGLLAAALGRPR--SAALDDLG-AL 58

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHE----------------TIQ 105
           +FAVR D      R   V  LRD+HT+    +D +     E                T  
Sbjct: 59  RFAVRID------RPGEV--LRDFHTLSSLFDDKKRFAPGEGRLPTASGGYRSAATSTQV 110

Query: 106 TWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGT 161
           T R YL DA F   L         + EL+ A+  P +  YLGRRSCP   PL LG 
Sbjct: 111 TERFYLADACFVAGL---EGDAAQLQELDDALRTPVFPLYLGRRSCPPDKPLRLGV 163


>UniRef50_B0S4B6 Putative uncharacterized protein n=1 Tax=Finegoldia magna ATCC
           29328 RepID=B0S4B6_FINM2
          Length = 228

 Score = 80.1 bits (196), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 66/239 (27%), Positives = 107/239 (44%), Gaps = 35/239 (14%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
           S ++L+ A P+Q+WG       R T  +PT+S ++GL+ A  G ++ DT S++ L+ S+ 
Sbjct: 2   SVILLKFASPLQSWGGLANYEIRNTEYYPTKSAVIGLVAAAFGYKKTDTESIKRLN-SLN 60

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDY-----RGLKSHETIQTWREYLCDASFT 117
           F+VR D+          + +RD+   +     Y             IQ +  Y+ DA F 
Sbjct: 61  FSVRIDQ--------KGSLIRDFQIAMEYNPKYMPNDPNYFVKSNLIQKY--YIQDAKFL 110

Query: 118 VALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQ-------------A 164
           +A  L+     ++ ++  A+  P Y  +LGR+S P+     +G                A
Sbjct: 111 IA--LSSDDETLMEDVYNALESPAYQLFLGRKSNPINADYLIGKFDGNELEIIKDYEWLA 168

Query: 165 SDPQKALLNYEPVGGDIYSEESVTGHHLKFTARD--EPMITLPRQFASR-EW-YVIKGG 219
           S   K  +  + V   I+S+   TG   K   RD  E      R F+SR E+ YV K G
Sbjct: 169 SKWYKKSIKKDSVELSIFSDYIDTGSKEKLIRRDLTESFENTKRDFSSRFEYRYVTKVG 227


>UniRef50_B2GBJ9 Putative uncharacterized protein n=1 Tax=Lactobacillus fermentum
           IFO 3956 RepID=B2GBJ9_LACF3
          Length = 235

 Score = 79.7 bits (195), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 60/173 (34%), Positives = 85/173 (49%), Gaps = 31/173 (17%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQR--DDTSSLQALSESVQ 62
           L++R+A P+Q++G P     R T R P++S ++G++GA LG +R  DD  SL  L     
Sbjct: 4   LVIRIAAPLQSYGDPASFEKRTTFRAPSKSAVIGMIGAALGFRRESDDYKSLNDLD---- 59

Query: 63  FAVRCDE--LILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           FAVR D+   +L D +++   L+             G  SH      R YL DA F VAL
Sbjct: 60  FAVRVDQPGEVLSDFQITHYSLKK-----------PGKLSH------RIYLQDAVFMVAL 102

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLN 173
                A M   E+E A+  P++  Y GRRS P    L +  C    P K  +N
Sbjct: 103 SSKQDALM--EEIEYALRHPKFQLYFGRRSNPPAGILKMKMC----PDKTAIN 149


>UniRef50_Q5YRB6 Putative uncharacterized protein n=1 Tax=Nocardia farcinica
           RepID=Q5YRB6_NOCFA
          Length = 235

 Score = 79.0 bits (193), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 55/173 (31%), Positives = 87/173 (50%), Gaps = 19/173 (10%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
           + L+LRLA P+Q+WG  +    R T ++P++SG+LGL+ A  G +R D   ++   +++ 
Sbjct: 2   TVLLLRLAAPLQSWGVASRFARRETQQYPSKSGILGLIAAARGHRRTD--PIEEALQNLA 59

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWL 122
           F VR D+            +RD+   L         K+ +   + R YL DA F  A+  
Sbjct: 60  FGVRVDQ--------PGRLIRDFQVALNID------KTKQFPLSQRYYLADAVFLAAI-- 103

Query: 123 TPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYE 175
                 +I  +  A+ +P +  YLGRRSCP+T PL LG  +    + AL   E
Sbjct: 104 -QGERGLIEGIGNALRRPEFPLYLGRRSCPVTGPLVLGEPRDVTLEHALHETE 155


>UniRef50_B3E5U9 CRISPR-associated protein Cas5 family n=2 Tax=Desulfuromonadales
           RepID=B3E5U9_GEOLS
          Length = 271

 Score = 79.0 bits (193), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 81/239 (33%), Positives = 111/239 (46%), Gaps = 40/239 (16%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
           YL+ RL GP+ +WG+     +R +  +P +S LLGL+ A LGI+RD+     AL+   +F
Sbjct: 3   YLLFRLYGPLASWGEIAVGESRHSAVYPGKSALLGLIAAALGIRRDEEQRQAALASGYRF 62

Query: 64  AVRCDELILDDRRVSVTG--LRDYHT----------VLGARED--YRGLKSHETIQTWRE 109
           AV          +V  TG  LRDYHT          V   R D    G +   TI + RE
Sbjct: 63  AV----------KVISTGHPLRDYHTAQAPDSVGKFVYRTRRDELVLGKERLGTILSSRE 112

Query: 110 YLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQK 169
           Y CDA   VA+     A   + E+ +A++KPR+  YLGR+SCP+  PL      A     
Sbjct: 113 YRCDAFSLVAVVAEDDAPYSLDEIREALMKPRFHLYLGRKSCPVAAPLNPLVRDAVGFGD 172

Query: 170 ALLNYEPVGGDIYS--------EESVTGHHL-------KFTARDEPMITLPRQFASREW 213
           AL +Y P G    S        +E V G  L       KF+  DE +    +Q     W
Sbjct: 173 ALDSY-PYGALFVSSWLMKTAQKEIVEGGKLAEVPSLAKFSREDETVFAYNKQPVRYYW 230


>UniRef50_A3EQA4 CRISPR-ssociated protein, Cas5 n=3 Tax=Bacteria RepID=A3EQA4_9BACT
          Length = 227

 Score = 78.6 bits (192), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 55/177 (31%), Positives = 88/177 (49%), Gaps = 22/177 (12%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           L++RL  PMQ+WG  +    R TG+ P++SG++GLL A LGI R++   L+ L+  +   
Sbjct: 4   LLIRLVSPMQSWGTSSRFDQRDTGKEPSKSGVIGLLAAALGIDRNNWDDLEPLA-GLSMG 62

Query: 65  VRCDELILDDRRVSVTGL--RDYHT---VLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
           VR D            G+  RDY T   ++ A       K H T  T+REYL DA F V 
Sbjct: 63  VRHDR----------PGIPRRDYQTASKIISADHS----KIHPTAVTYREYLADAVFLVG 108

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEP 176
                    ++ ++  A+  P +  +LGR+S   + P+++     + P +  L + P
Sbjct: 109 --FESAEVSLLEKINSALKNPVWPLFLGRKSYVPSEPIWIENGLKNVPLREALEHFP 163


>UniRef50_B0TDU1 Crispr-associated protein cas5 n=1 Tax=Heliobacterium modesticaldum
           Ice1 RepID=B0TDU1_HELMI
          Length = 230

 Score = 77.8 bits (190), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 56/159 (35%), Positives = 82/159 (51%), Gaps = 17/159 (10%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           L LRL GP+Q+WG  +    R +   PT+SG++GLLG  LG  R+D   L++L  +++  
Sbjct: 6   LALRLEGPLQSWGSRSRWDYRDSALEPTKSGIIGLLGCALGWSRND-KRLESLDAALRLT 64

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHE-----TIQTWREYLCDASFTVA 119
           VR D+          T L D+HTV G      G +        T+ + R YL +ASF   
Sbjct: 65  VRIDK--------PGTPLIDFHTVQGYLLMAEGKQKKSGNDMYTVVSRRVYLQEASF--- 113

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLF 158
           L L       + + +KA+  P +  +LGR+SCP   PLF
Sbjct: 114 LALLTGEQGALHQCKKALNDPVWPVFLGRKSCPPARPLF 152


>UniRef50_C9M9R7 CRISPR-associated protein Cas5, Ecoli subtype n=1 Tax=Jonquetella
           anthropi E3_33 E1 RepID=C9M9R7_9BACT
          Length = 243

 Score = 77.0 bits (188), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 56/176 (31%), Positives = 90/176 (51%), Gaps = 11/176 (6%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
           +L+LR  GPM ++G    +  RP  RFP  S + GL+   LG    +T  LQAL + +  
Sbjct: 3   FLVLRFRGPMMSFGDVAVDEQRPIDRFPGVSMVTGLVANALGWDWSETEKLQALQDRLVL 62

Query: 64  AVRCD---ELILDDRRVSV---TGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFT 117
           AVR D   E + + + V++   +GL   H++  +    R L    T+Q +  Y  ++  T
Sbjct: 63  AVREDRAGERLREYQTVALPGKSGLFVTHSIPCS----RNLDKPMTVQKYLSYWANSLIT 118

Query: 118 VALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTC-QASDPQKALL 172
             + LT   T  + E+  A+ KP    +LGR++C  T P+F G    A  P++A+L
Sbjct: 119 CFIALTGLGTPTLDEIACALKKPARPLFLGRKTCLPTEPVFRGEIFGAESPEEAVL 174


>UniRef50_A5GBK2 CRISPR-associated protein Cas5 family n=2 Tax=Deltaproteobacteria
           RepID=A5GBK2_GEOUR
          Length = 231

 Score = 76.6 bits (187), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 55/170 (32%), Positives = 87/170 (51%), Gaps = 12/170 (7%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
           +S+L LRL GP+Q+WG  +    R TG  PT+S + G+  A LG  R      + L   V
Sbjct: 10  KSFLALRLEGPLQSWGFDSQYNRRNTGLMPTKSAIAGMCCAALGFLRGCDKEQEFL---V 66

Query: 62  QF-AVRCDELIL----DDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASF 116
            F AVR   + +      + + V  L+DYHTV   R    G  +++ + T R+YL DA+F
Sbjct: 67  AFGAVRMTAIAIPRNGAKKELPVRRLQDYHTVQNTRR-ASGAINNDCVLTHRQYLTDAAF 125

Query: 117 TVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASD 166
            V   L    + ++ ++  A+  P +  +LGR++C  T P+  G  +  D
Sbjct: 126 GV---LLEGDSTLLKQIAAALENPVWGVWLGRKTCIPTAPVLAGLRENRD 172


>UniRef50_D1Y486 Crispr-associated protein Cas5 n=1 Tax=Pyramidobacter piscolens
           W5455 RepID=D1Y486_9BACT
          Length = 269

 Score = 76.3 bits (186), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 68/226 (30%), Positives = 97/226 (42%), Gaps = 36/226 (15%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           LILRL GP+ A+G    +  RPT   P  S + GL+   LG    D   LQ L E ++ A
Sbjct: 4   LILRLRGPLMAFGDVAVDEIRPTDLLPGLSEMTGLIANALGWTFQDVEKLQRLQERLRLA 63

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGARED--YR----------GLKSHETIQTWREYLC 112
            R D       R  V  LRDY T   + ED  +R          G K   T+Q +R Y  
Sbjct: 64  SRED-------RTGVP-LRDYQTARLSSEDSLWRTDGIVAERGGGSKGEFTVQRYRHYRA 115

Query: 113 DASFTVALWLTP-HATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKAL 171
           DA+ TV + L P      + E+  A+  P    ++GR  CP + P+    C         
Sbjct: 116 DAAVTVLIALDPADEAPALEEIRDALRHPARPLFIGRIGCPPSQPI----C--------- 162

Query: 172 LNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIK 217
             +EP G +I   +S+    +  T R        R+ ASR   +++
Sbjct: 163 --FEPEGREIIHTDSLKDAIMHITPRAPLGAQTKREPASRNKVLVE 206


>UniRef50_D0WFC8 CRISPR-associated protein Cas5 n=1 Tax=Slackia exigua ATCC 700122
           RepID=D0WFC8_9ACTN
          Length = 267

 Score = 76.3 bits (186), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 53/161 (32%), Positives = 89/161 (55%), Gaps = 17/161 (10%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
           + L+L+LA P+Q+WG  +    R T   P++SG++GLL A LG +R+D+    A   +++
Sbjct: 5   TVLLLKLAAPLQSWGASSRFTERTTRHEPSKSGVIGLLAAALGRRREDSVDDLA---ALR 61

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAR--EDYRGLKSHETIQ-TWREYLCDASFTVA 119
           FAVR D+          + +RD+ T    +   D R    +E++  + R+YL DA F  A
Sbjct: 62  FAVRIDQ--------PGSFMRDFQTEHTRKWDSDTRRFVFNESLSLSKRDYLSDAVFVAA 113

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLG 160
           L        +++E  +A+  P +  +LGRRSCP +  ++LG
Sbjct: 114 L---EGDEDLLAECAEALHHPAFPLFLGRRSCPPSTQVYLG 151


>UniRef50_B1VIY0 CRISPR-associated protein n=9 Tax=Actinomycetales
           RepID=B1VIY0_CORU7
          Length = 240

 Score = 76.3 bits (186), Expect = 8e-13,   Method: Compositional matrix adjust.
 Identities = 56/175 (32%), Positives = 94/175 (53%), Gaps = 18/175 (10%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M   L+L L GPMQ+WG  +    R T   PT+SG++GL+ A  G +R  T  ++ L++ 
Sbjct: 1   MAHSLLLLLKGPMQSWGDESRFSVRATATTPTKSGIVGLIAAAQGRRR--TDGVEDLAK- 57

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           ++ AVR D+        S + LRDY T   A+   +   ++ ++ T R +L DA+F  A 
Sbjct: 58  LRMAVRVDQ--------SGSLLRDYQT---AQPWLKNPGANASLVT-RYFLSDAAFVAA- 104

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYE 175
            +      ++ ++ +A+ +P Y  Y+GRRSCP+   L +G     D + AL  ++
Sbjct: 105 -VESEDRELLDQMAEALRRPAYPLYMGRRSCPVHPGLVIGVVDG-DAESALRAHD 157


>UniRef50_D2RB02 CRISPR system CASCADE complex protein CasD n=3 Tax=Actinobacteria
           (class) RepID=D2RB02_GARVA
          Length = 291

 Score = 76.3 bits (186), Expect = 8e-13,   Method: Compositional matrix adjust.
 Identities = 58/176 (32%), Positives = 86/176 (48%), Gaps = 16/176 (9%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRD-DTSSLQALSE 59
           M+S L+L+ +GP+Q+WG  +   TR T  +P++S ++G++ A  G +R  D     A   
Sbjct: 1   MKS-LLLKFSGPLQSWGTDSHFETRHTDYYPSKSAVIGMIAAAFGYRRSTDCDENIAKLN 59

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
            + FAVR D+            LRDYH  + A+    G    +   T R YL DA F VA
Sbjct: 60  DLDFAVRIDQ--------QGNLLRDYH--IAAKYKANG-DFEKNYVTNRYYLEDAIFLVA 108

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYE 175
             +  +   +I ++  A+  P +   LGRRS P T    LG       Q ALL +E
Sbjct: 109 --IGSNNEQLIYDISNALRSPYFQSSLGRRSLPPTADFILGVEDCGVIQ-ALLTHE 161


>UniRef50_C9M2Y8 CRISPR-associated protein n=1 Tax=Lactobacillus helveticus DSM
           20075 RepID=C9M2Y8_LACHE
          Length = 241

 Score = 75.9 bits (185), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 47/165 (28%), Positives = 82/165 (49%), Gaps = 16/165 (9%)

Query: 7   LRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVR 66
           +RL  P+Q++G       R +  +P++S ++G++ A LG +RDD   LQ    ++ FAVR
Sbjct: 6   IRLTAPLQSYGNQASFNQRTSDNYPSKSAVIGIIAAALGYRRDDARILQL--NNLLFAVR 63

Query: 67  CDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPHA 126
            ++        S   + ++ TV   +   +  +      T+RE++ DA F VA  +    
Sbjct: 64  IEQ--------SGNMMTEFQTVEYQKSSTKTARKL----TYREFIQDAVFMVA--IGSDN 109

Query: 127 TMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKAL 171
              I ++  A+  P++  YLGRRS P   PL + T    +P + L
Sbjct: 110 DHEIEKIVSALKHPKFQLYLGRRSNPPAGPLMIETYDEENPLQVL 154


>UniRef50_UPI0001AF1D4C CRISPR-associated protein, CT1976 n=1 Tax=Streptomyces ghanaensis
           ATCC 14672 RepID=UPI0001AF1D4C
          Length = 244

 Score = 73.6 bits (179), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 54/153 (35%), Positives = 78/153 (50%), Gaps = 13/153 (8%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           L++    PMQ+WG  +   +R T   PT+SG++GLL A LGI RD    +Q L+E ++  
Sbjct: 4   LLMCFDAPMQSWGTRSQFASRDTATEPTKSGVVGLLAAALGIPRDADEEIQNLAE-LRMG 62

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTP 124
           VR       DR   V    D+HTV     +  G K+H T  T R YL DA F V   +  
Sbjct: 63  VRV------DREGVVEA--DFHTVQNV-PNTEG-KNHRTAVTKRFYLADALFLVG--VES 110

Query: 125 HATMVISELEKAVLKPRYTPYLGRRSCPLTHPL 157
             T ++ +L  A+  PR+  Y GR++     P+
Sbjct: 111 DDTQLLHQLHTALTAPRWPLYFGRKAFVPARPI 143


>UniRef50_A8M404 CRISPR-associated protein Cas5 family n=1 Tax=Salinispora arenicola
           CNS-205 RepID=A8M404_SALAI
          Length = 238

 Score = 72.8 bits (177), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 56/160 (35%), Positives = 82/160 (51%), Gaps = 26/160 (16%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE--SVQ 62
           L+LRLAGP+Q+WG  +    R T   PT+SG++G+L A  G++R D      L+E  S+ 
Sbjct: 2   LLLRLAGPLQSWGATSRFTHRHTQVTPTKSGVIGMLAAASGLRRTD-----PLTELLSLD 56

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQ-TWREYLCDASFTVALW 121
           F VR D+            LRD+          R L   +++  T R YL DA F VA+ 
Sbjct: 57  FGVRIDQ--------PGQLLRDFQVA-------RTLDGRDSMPLTNRYYLSDAVFLVAIG 101

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGT 161
                  ++  L ++V +P +  YLGRR+CP   P+ LG 
Sbjct: 102 ---GDQALLEGLHESVRRPHFPLYLGRRACPPVAPISLGV 138


>UniRef50_B4UE71 CRISPR-associated protein Cas5 family n=2 Tax=Anaeromyxobacter
           RepID=B4UE71_ANASK
          Length = 246

 Score = 71.2 bits (173), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 58/186 (31%), Positives = 89/186 (47%), Gaps = 6/186 (3%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M   LILR   P+ A+G    +     G FP  S + GL+   LG    D   L+AL   
Sbjct: 1   MLDALILRFDAPLLAFGGVAVDNHGEVGDFPGLSMVAGLIANALGYDHRDCDRLEALQRR 60

Query: 61  VQFAVRCD---ELILDDRRVSVTG--LRDYHTVLGAREDYRGLKSHETIQTWREYLCDAS 115
           ++ AVR D   + ++D + V++    L    T  GA E   G  S  T   +R Y  DA 
Sbjct: 61  LRIAVRRDRSGQRLVDFQTVALGQPFLERGWTTRGAVEGRDGAFSDGTHIRYRAYWADAV 120

Query: 116 FTVALWLTPHA-TMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNY 174
           +T+A+ L P A +  +  +E+A+ +P    +LGR++C  + P+  G  Q      AL ++
Sbjct: 121 YTLAVTLDPPAESPGLDAVERALREPERPLFLGRKACLPSVPILAGRLQIPSLLAALASF 180

Query: 175 EPVGGD 180
           E V  D
Sbjct: 181 ERVSKD 186


>UniRef50_D0MET6 CRISPR-associated protein Cas5 family n=1 Tax=Rhodothermus marinus
           DSM 4252 RepID=D0MET6_RHOM4
          Length = 252

 Score = 70.9 bits (172), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 57/184 (30%), Positives = 90/184 (48%), Gaps = 25/184 (13%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           L+LR   P+ ++G P  +       +P  S + GLL   LG    +T+ L+ L E +++A
Sbjct: 4   LLLRFDAPLMSFGAPIVDQYGFIQPYPALSMMTGLLANALGYTHAETARLERLQERLRYA 63

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAR---EDYRGLKSHETIQT-------------WR 108
           VR      +DRR     LRD+ TV  ++    D R   +  T++T              R
Sbjct: 64  VR------EDRRGQ--QLRDFQTVDLSQPFLHDERAWTTRGTLETRQGGTASLGIHIRLR 115

Query: 109 EYLCDASFTVALWLT-PHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDP 167
           +Y  DA +TVAL L  P     +++LE+A+  P    ++GR+ C    PLF+G  +A+D 
Sbjct: 116 DYWADAVYTVALTLDPPDEPPTLADLEQALRFPARPLFIGRKPCLPAAPLFIGRVEAADL 175

Query: 168 QKAL 171
             AL
Sbjct: 176 LDAL 179


>UniRef50_Q0BSC7 Putative uncharacterized protein n=1 Tax=Granulibacter bethesdensis
           CGDNIH1 RepID=Q0BSC7_GRABC
          Length = 225

 Score = 70.1 bits (170), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 62/204 (30%), Positives = 94/204 (46%), Gaps = 37/204 (18%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRD-DTSSLQALSESVQ 62
           +L+  LA  + + G+      R +  +PTRS ++GL+GA LGI+RD D S+L  LS    
Sbjct: 6   FLVFGLAASLGSMGELAGHERRGSLIWPTRSAIIGLMGAALGIERDGDFSALDVLS---- 61

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLG--------------AREDYRGLKSHETIQTWR 108
                D  I D    +   LRDYHT+                A  D RG  +  T  T R
Sbjct: 62  ----IDVAIFD----AGAPLRDYHTIETIPSAAAKNPNSRPEALRDARGRTN--TAITHR 111

Query: 109 EYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQ 168
           +Y     + +A+         +  +  A+L+P +T Y+GR+SCPL  P      +A   +
Sbjct: 112 DYRTSVFYGIAV-----RGAGLERIVAALLEPHFTLYVGRKSCPLAAPTGAKIVEAVSAE 166

Query: 169 KALLNYEPVGGDIYSEESVTGHHL 192
            AL   E +   ++ +ESV  H L
Sbjct: 167 AAL---EHLKAPLWRKESVKAHLL 187


>UniRef50_B8GIV3 CRISPR-associated protein Cas5 family n=1 Tax=Methanosphaerula
           palustris E1-9c RepID=B8GIV3_METPE
          Length = 257

 Score = 69.7 bits (169), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 64/182 (35%), Positives = 86/182 (47%), Gaps = 22/182 (12%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
           YL   L G M +WG       RPT   PTRS +LGLL A LGI+RD+   L AL+ + + 
Sbjct: 6   YLTFSLYGMMASWGDIAVGEYRPTADHPTRSAVLGLLAAALGIRRDEEERLAALTRAYKV 65

Query: 64  AVRCDELILDDRRVSVTGLRDYHTVL---GAREDYRGLKSHE----------TIQTWREY 110
           A+R D             LRDYHT      A++  + L   +          TI + R+Y
Sbjct: 66  AIRVD--------APGMLLRDYHTTQVPSAAKKGRQYLTRKDELAAPREVLNTILSTRDY 117

Query: 111 LCDASFTVALWLTPHA-TMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQK 169
            CDA + V +W    A    +  L + +  P +T YLGR+SCPL  P+      A D   
Sbjct: 118 RCDAVYRVYIWCRDTAPPYSLKTLAEHLQHPVFTLYLGRKSCPLALPVNPEVKTAPDLLT 177

Query: 170 AL 171
           AL
Sbjct: 178 AL 179


>UniRef50_A1ARH6 CRISPR-associated protein, Cas5e family n=2 Tax=Bacteria
           RepID=A1ARH6_PELPD
          Length = 232

 Score = 68.9 bits (167), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 50/146 (34%), Positives = 75/146 (51%), Gaps = 6/146 (4%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           L+LRL GPMQ+WG  +    R TG+ P++SG++GLL A LGI R++   L+ L+  +   
Sbjct: 4   LLLRLVGPMQSWGTTSRFDQRDTGKEPSKSGVVGLLAAALGIDRENWVDLEPLT-CLAMG 62

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTP 124
           VR D   +  R     G     T++ A  D    K    +   R YL DA+F V L    
Sbjct: 63  VRHDRPGVPKRDYQTAGCASTDTIIKA--DGTQAKGGGVVSQ-RFYLADAAFLVGLECDD 119

Query: 125 HATMVISELEKAVLKPRYTPYLGRRS 150
           +   ++  +  A+  P +T  LGR+S
Sbjct: 120 NC--LLERIHVALHNPFWTLALGRKS 143


>UniRef50_B5GY62 Crispr-associated protein (Fragment) n=1 Tax=Streptomyces
           clavuligerus ATCC 27064 RepID=B5GY62_STRCL
          Length = 260

 Score = 68.9 bits (167), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 67/175 (38%), Positives = 86/175 (49%), Gaps = 29/175 (16%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDD-TSSLQALSESVQF 63
           L+LRLAGP+Q+WG  +   +R TG  PT+SG++GLL A  G  R      L+AL    + 
Sbjct: 86  LLLRLAGPLQSWGSASAFNSRQTGAEPTKSGVIGLLAAADGRARGACIEDLRAL----RL 141

Query: 64  AVRCDELILDDRRVSVTGLRDYHTV------------LGAREDYRGLKSHETIQ-TWREY 110
            VR D         S T LRDYHT             +GA+   R     +  Q T R Y
Sbjct: 142 GVRVDR--------SGTLLRDYHTASDHRGRPLAQAGVGAKGTQRPTSPAKYTQVTTRYY 193

Query: 111 LCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQAS 165
           L DA F  AL   P A  ++  L++AV  P +   LGRRSC  + PL LG    S
Sbjct: 194 LQDAVFLAAL-AGPRA--LLDRLDRAVRAPAFPLALGRRSCVPSLPLALGVHPGS 245


>UniRef50_A9HLC6 CRISPR-associated protein Cas5 family n=11 Tax=Acetobacteraceae
           RepID=A9HLC6_GLUDA
          Length = 260

 Score = 68.6 bits (166), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 53/170 (31%), Positives = 74/170 (43%), Gaps = 21/170 (12%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M  +L   +  PM ++G       R     P RS +LGL+ ACLG+ RDD  +  AL+  
Sbjct: 1   MGQFLTFAMVAPMASFGAIAVGERRDGWDRPARSAVLGLMAACLGLTRDDEDAQAALAAD 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLG--AREDYRGLKSHE----------TIQTWR 108
              A+ C              L DYHT     AR ++R     E          TI + R
Sbjct: 61  YGLAILC--------HAPGKLLTDYHTAQAAPARRNWRPATRAEELAASPGDLATILSRR 112

Query: 109 EYLCDASFTVALWLTPH-ATMVISELEKAVLKPRYTPYLGRRSCPLTHPL 157
           +Y        A+W +   A   +  L+ A+ +P +TP LGRRSCP   PL
Sbjct: 113 DYRMGTWHLGAVWTSGKTARWSLEALQAAMREPVFTPSLGRRSCPAGLPL 162


>UniRef50_B6B783 CRISPR-associated protein Cas5, Ecoli subtype n=1
           Tax=Rhodobacterales bacterium Y4I RepID=B6B783_9RHOB
          Length = 232

 Score = 68.6 bits (166), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 59/185 (31%), Positives = 82/185 (44%), Gaps = 32/185 (17%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRD-DTSSLQALSE 59
           M  YLI +L   + A G+      R +   P RS ++G LGA +G++RD D S L AL  
Sbjct: 1   MPEYLIFQLVAAIGAMGEFGGHDRRGSLTLPGRSAVIGTLGAAMGLRRDADFSGLDALGV 60

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGA------REDYR-------GLKSHETIQT 106
           +V    +                RDYHTV         R   R       G K + T+ T
Sbjct: 61  AVASFGKTAP------------FRDYHTVQTVPSAAVKRPQSRPQALRDAGRKVNTTL-T 107

Query: 107 WREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASD 166
            R+Y  D  F VA+W        ++EL  A+  P +  +LGR+SCPL+ P       A+ 
Sbjct: 108 SRDYRADCVFGVAIW-----GEGLAELASALSAPVFQTFLGRKSCPLSAPFDPQIVAAAT 162

Query: 167 PQKAL 171
           P  AL
Sbjct: 163 PSAAL 167


>UniRef50_Q0AA33 CRISPR-associated protein Cas5 family n=2 Tax=Gammaproteobacteria
           RepID=Q0AA33_ALHEH
          Length = 242

 Score = 67.4 bits (163), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 59/187 (31%), Positives = 81/187 (43%), Gaps = 25/187 (13%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           LILRL  P+ ++G    +   PT RFP RS L G+L   LG    DT +L +L   + +A
Sbjct: 4   LILRLDAPLMSFGGVLVDQHNPTDRFPGRSMLTGMLANALGWHHQDTEALNSLQARISYA 63

Query: 65  VRCDELILDDRRVSVTGLRDYHTV--------------LGAREDYRGLKSHETI-QTWRE 109
            R D        V    LRDY TV               GA E   G  +   I Q  R 
Sbjct: 64  ARWD--------VPPEPLRDYQTVDLGQTHLANPGWTTRGAPEHREGGTAKRGIHQRDRH 115

Query: 110 YLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQK 169
           Y  +   TVA+ + P    V + L  A+  P    ++GR++C    P+ L   + SD   
Sbjct: 116 YWANGVMTVAVTVPPGEPNVAT-LAAALRHPARPLFIGRKACLPAAPVLL-RVRESDDAY 173

Query: 170 ALLNYEP 176
            +L  EP
Sbjct: 174 HVLASEP 180


>UniRef50_C2KP44 Putative uncharacterized protein n=1 Tax=Mobiluncus mulieris ATCC
           35243 RepID=C2KP44_9ACTO
          Length = 245

 Score = 67.0 bits (162), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 56/176 (31%), Positives = 78/176 (44%), Gaps = 26/176 (14%)

Query: 7   LRLAGPMQAWGQPTFEGT-RPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAV 65
           +RLAGP+Q+W      G    T  +PTR  L GL+ ACLG  R          + +QFAV
Sbjct: 6   IRLAGPLQSWAGAKVSGNISHTQDYPTRGSLEGLVAACLGCPR---GKYPLWFQDLQFAV 62

Query: 66  RCDE--LILDDRRVSVTGLRDYHT---------VLGAREDYRGL-----KSHETIQTWRE 109
           R D    I DD +    G+RD            + G R   RGL        +T    R 
Sbjct: 63  RVDSPGRICDDYQ--TIGVRDEDMQVATRLLTLLTGKRATNRGLAFIPDAQGKTTIVRRT 120

Query: 110 YLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQAS 165
            L DA F V +    H    + +L++A+  P +  YLGR++     P +LG  + S
Sbjct: 121 LLADAEFIVQIQCEGH----LEQLDQAISDPTFVSYLGRKAFAPGFPFYLGIGEDS 172


>UniRef50_Q1J367 CRISPR-associated protein, CT1976 n=1 Tax=Deinococcus geothermalis
           DSM 11300 RepID=Q1J367_DEIGD
          Length = 232

 Score = 67.0 bits (162), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 56/158 (35%), Positives = 79/158 (50%), Gaps = 18/158 (11%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
           + L+LRL  PMQAWG  +    R T   P++SG+LGL  A LGI R D  S++ L+  + 
Sbjct: 2   ATLLLRLVAPMQAWGTRSRFDDRDTEAEPSKSGVLGLCAAALGIDRAD--SVEHLAR-LA 58

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWL 122
           F VR D       R  V G  DYHT     +   G     T  T R YL DA+F   L  
Sbjct: 59  FGVRVD-------REGVAGT-DYHTA----QLRPGNPRTRTDVTRRAYLADAAFWAGL-- 104

Query: 123 TPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLG 160
                 ++++L+ A+  P +   LGR++ P + P+  G
Sbjct: 105 -EGDAGLLTDLDAALHNPHWPLSLGRKAFPPSLPICAG 141


>UniRef50_Q2FNU0 CRISPR-associated protein, CT1976 n=1 Tax=Methanospirillum hungatei
           JF-1 RepID=Q2FNU0_METHJ
          Length = 225

 Score = 66.6 bits (161), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 44/148 (29%), Positives = 71/148 (47%), Gaps = 9/148 (6%)

Query: 35  GLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDE--LILDD----RRVSVTGLRDYHTV 88
            +LG++ A LGI+RDD  +   L     F+V   +  +++ D    + V  + L+  + V
Sbjct: 15  AVLGMVAAALGIRRDDEEAQNRLQAGYGFSVMVLQPGIMIQDFHTIQSVHSSSLKKMNHV 74

Query: 89  LGAREDYRGLKSHETIQTWREYLCDASFTVALWL--TPHATMVISELEKAVLKPRYTPYL 146
           +  R D   L   ETI + REYLCD      +W+     A   + E+  +   P +  YL
Sbjct: 75  M-TRRDEMNLGDSETILSRREYLCDHVSVACVWIRDAESAQFSLEEIAASFRNPVFCLYL 133

Query: 147 GRRSCPLTHPLFLGTCQASDPQKALLNY 174
           GR+SCP   P+     QA   + AL+ +
Sbjct: 134 GRKSCPPALPVHARVIQADSLKSALVQH 161


>UniRef50_C2GEY8 CRISPR-associated protein n=1 Tax=Corynebacterium glucuronolyticum
           ATCC 51866 RepID=C2GEY8_9CORY
          Length = 242

 Score = 65.1 bits (157), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 55/184 (29%), Positives = 84/184 (45%), Gaps = 39/184 (21%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTR-PTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE 59
           M S   +RL+GP+Q+W   +  G    T   PT +GL GLL   LG +RD+   +     
Sbjct: 1   MPSSTFIRLSGPIQSWAGQSVSGNFIRTNPIPTLTGLRGLLAGALGARRDE---IPEWIS 57

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGARE---DYR-------GLKSHETIQ---- 105
            V+F+VR D+        + + + D+ T+ G+RE   D+R       G+K+    Q    
Sbjct: 58  KVRFSVREDQ--------TGSFVDDFQTI-GSREEEWDFRRRIAILQGMKARSIKQLSFK 108

Query: 106 --------TWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPL 157
                     R YL +A F V +    H      E++ A   P +  YLGR++ P   P 
Sbjct: 109 PAVGANAVVRRTYLSEAEFIVRVTDERHT----EEIDHAFSSPVFATYLGRKAFPAAFPF 164

Query: 158 FLGT 161
           +LGT
Sbjct: 165 YLGT 168


>UniRef50_Q03C60 CRISPR-associated protein n=4 Tax=Lactobacillus RepID=Q03C60_LACC3
          Length = 236

 Score = 64.7 bits (156), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 50/161 (31%), Positives = 78/161 (48%), Gaps = 20/161 (12%)

Query: 7   LRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVR 66
           +RL  P+Q++G       R TG +P++S ++G+L A LG QRDD  ++ AL++ + FAVR
Sbjct: 6   IRLTSPLQSYGNEAQFARRTTGDYPSKSAIIGMLAAALGYQRDD-PAINALNDLL-FAVR 63

Query: 67  CDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPHA 126
            D+            + ++ T           K      T+R+ L DA F VA+     A
Sbjct: 64  VDQ--------PGQVMTEFQTA--------EWKPGTRKLTYRDLLQDAVFVVAIGSEDEA 107

Query: 127 TMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDP 167
            +    L +A+  PR+  YLGRR+      L + T    DP
Sbjct: 108 WL--DRLAEALRHPRFQLYLGRRANVPAGVLKIQTFAGQDP 146


>UniRef50_UPI0001B51C2B CRISPR-associated Cas5 family protein n=1 Tax=Streptomyces
           viridochromogenes DSM 40736 RepID=UPI0001B51C2B
          Length = 278

 Score = 63.5 bits (153), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 62/199 (31%), Positives = 88/199 (44%), Gaps = 52/199 (26%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M S L+LRLAGP+Q+WG       R T   PT+SG+ GL+ A LG+ R D   L AL++ 
Sbjct: 1   MTSVLLLRLAGPLQSWGALARFDRRDTLNRPTKSGVTGLVAAALGLDRAD--DLGALTD- 57

Query: 61  VQFAVRCD----------------------ELILDDRRV--------SVTG-------LR 83
           ++FAVR D                      +LI D RR         + TG        R
Sbjct: 58  LRFAVRADRPGTAVRDFHIVGSGTYPLRPRDLITDHRRAEKAAAALETSTGPVFGHLAAR 117

Query: 84  DYHTVLGAREDY----------RGLKSHETIQTWREYLCDASFTVALWLTPHATMVISEL 133
                 GA ++            G  + + + T R YL DA+F  A+   P   + +  +
Sbjct: 118 SVTKWYGAPKEIAPDPKTGVLLAGNTTRDAMMTTRWYLADAAFVAAV-EHPDQNL-LHRI 175

Query: 134 EKAVLKPRYTPYLGRRSCP 152
             AV  P+   +LGR+SCP
Sbjct: 176 SHAVEHPKRLLWLGRKSCP 194


>UniRef50_B5F422 CRISPR-associated protein Cas5 n=59 Tax=Enterobacteriaceae
           RepID=B5F422_SALA4
          Length = 248

 Score = 61.6 bits (148), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 55/161 (34%), Positives = 79/161 (49%), Gaps = 19/161 (11%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M  YL+ +L GPM +WG       R +   P+RS LLGLL A LGI+RD+   L A +  
Sbjct: 1   MSQYLVFQLHGPMASWGVDAPGEVRHSHELPSRSALLGLLAAALGIRRDEEERLNAFNRH 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGARE--DYRGLKSHETIQ---------TWRE 109
            QF + C          +    RDYHTV   +E    R     E +Q         + R+
Sbjct: 61  YQFLL-CAS-------GNPRWARDYHTVQMPKEVRKARYFSRREELQDPELLSALISRRD 112

Query: 110 YLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRS 150
           Y  DA + +A+  TP A   +++L+ A+  P +  YLGR+S
Sbjct: 113 YYTDAWWMIAVSATPDAPYTLAQLQAALQHPVFPLYLGRKS 153


>UniRef50_B4S8P8 CRISPR-associated protein Cas5 family n=8 Tax=Bacteria
           RepID=B4S8P8_PROA2
          Length = 243

 Score = 60.5 bits (145), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 53/179 (29%), Positives = 80/179 (44%), Gaps = 28/179 (15%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
           YL+L L  P+Q+WG  +  G R T  FPT+SG+LG+L   LG   +    L+ ++   Q 
Sbjct: 5   YLLLWLEAPLQSWGADSRFGRRGTLEFPTKSGVLGMLCCSLGAGGEQKELLEKMAPLKQS 64

Query: 64  AV--------RCDELILDDRRVSVTGLRDYHTVLGAREDYRGL-------KSHETIQ--- 105
           A+        R +E+   DR      LRD+H V    +D           KS  T     
Sbjct: 65  AISFCRTSKFRQEEIKKLDRE---PLLRDFHMVGSGYDDKNPWETLLIPKKSDGTTAVNG 121

Query: 106 ----TWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLG 160
               T+R YL DA F V + +      + ++   A+  P +  Y GR+ C  T  ++ G
Sbjct: 122 GSKITYRYYLQDAVFAVIMEVPSEKLTLFAD---ALENPCWDIYFGRKCCAPTDFIYRG 177


>UniRef50_C5V9N1 CRISPR-associated protein Cas5 n=1 Tax=Corynebacterium matruchotii
           ATCC 14266 RepID=C5V9N1_9CORY
          Length = 223

 Score = 60.5 bits (145), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 58/201 (28%), Positives = 85/201 (42%), Gaps = 37/201 (18%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGT--RPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALS 58
           M   L +RLAGP+Q+W  P   G   R   R PTRSGL+GLL    G  R +        
Sbjct: 1   MTEALYIRLAGPLQSWAGPAITGNFVRTEPR-PTRSGLVGLLAGACGYGRGEYPEWLT-- 57

Query: 59  ESVQFAVRCDE--LILDD---------------RRVSVTGLRDYHTVLGAREDYRGLKSH 101
             + F +R D    ++DD               R +   G R    +L +  D +GL   
Sbjct: 58  -QLHFQIREDNRGTLVDDFHTINPRDTEEEFRSRLLLAMGQRPTKKLLNSTPDGQGL--- 113

Query: 102 ETIQTWREYLCDASFTVALWLTP--HATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFL 159
            T  T R Y+ D  F V +      H  ++  +L+    +P +  YLGR++   + P +L
Sbjct: 114 -TAITERTYIADGEFIVQIKAGSREHQELLAEKLQ----QPHFVTYLGRKAFAPSFPFYL 168

Query: 160 GTCQASDPQKALLNYEPVGGD 180
           G    + P   L     VGG+
Sbjct: 169 G----AGPDDTLARIPTVGGE 185


>UniRef50_B8IZA7 CRISPR-associated protein Cas5 family n=1 Tax=Desulfovibrio
           desulfuricans subsp. desulfuricans str. ATCC 27774
           RepID=B8IZA7_DESDA
          Length = 249

 Score = 60.5 bits (145), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 60/225 (26%), Positives = 100/225 (44%), Gaps = 42/225 (18%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQR---DDTSSLQALSESV 61
           L LRL  PM ++G  +    R T   P++S + G+L A  G+ R   ++ + LQ ++   
Sbjct: 8   LALRLQAPMLSFGNESRFNRRCTASLPSKSVVAGMLCAAKGLHRGSVEEQAFLQQVAAIP 67

Query: 62  QFAV---RCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV 118
             +V   RC      D  ++     D+HTV G R+   G+K      T R YL D+SF V
Sbjct: 68  MLSVAIPRCLSANGKDWLLAAGRTVDFHTVQGTRKAAGGIKDCHI--TTRHYLHDSSFAV 125

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVG 178
            L   P+   V+ +  +A+  P +  ++GR+ C  + P+F                    
Sbjct: 126 FLN-GPY--RVLEDAARALQNPVWGLWIGRKCCIPSAPVF-------------------- 162

Query: 179 GDIYSEESVTGHHLKFTARDEPMITLPRQFAS--REWYVIKGGMD 221
           G ++S E+V  +H         M+  P +F +  RE +  + G D
Sbjct: 163 GGLFSSEAVALNH---------MLDAPLEFFTHEREVHSFEDGND 198


>UniRef50_B6IWM3 CRISPR-associated protein, CT1976 family n=1 Tax=Rhodospirillum
           centenum SW RepID=B6IWM3_RHOCS
          Length = 280

 Score = 58.9 bits (141), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 57/191 (29%), Positives = 82/191 (42%), Gaps = 28/191 (14%)

Query: 3   SYLILRLAGPMQAWGQPTFEGT----RPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALS 58
           ++L   LA P  AWG  +        + T   P+RS L GLLGA LG++R   + L  LS
Sbjct: 6   AHLCFTLAAPYGAWGAASQSSATTAWKATELDPSRSALTGLLGAALGLER---AHLGRLS 62

Query: 59  ESVQFAVRCDELILDDRRVSVTGLRDYHTVLGA---------------REDYRGLKSHET 103
           E+++FAVR       D +       DYHT+  A               R    G K    
Sbjct: 63  EALRFAVRTGIRPTRDPQP------DYHTISRAHRPEGREHWSRFEELRPALAGGKQEGA 116

Query: 104 IQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQ 163
           + + REY     +TVA+     A + +  L +A+  P +  Y GR++C L  P       
Sbjct: 117 LLSRREYWSLGLWTVAVATLNPAGVPLDRLAQALRTPHWPLYAGRKACTLGLPPDPEVRT 176

Query: 164 ASDPQKALLNY 174
              P   LL+Y
Sbjct: 177 GPGPLSVLLDY 187


>UniRef50_B8IMR2 CRISPR-associated protein Cas5 family n=1 Tax=Methylobacterium
           nodulans ORS 2060 RepID=B8IMR2_METNO
          Length = 273

 Score = 58.5 bits (140), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 51/172 (29%), Positives = 68/172 (39%), Gaps = 29/172 (16%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M + L+  L  P    G       R +   P RS +LGL+   LGI R D +   AL   
Sbjct: 1   MPAGLVFTLYAPFAGMGDVAVGEERGSFDRPARSAVLGLVAGALGIDRADEAGHAALDRG 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTV----------LGAREDYRGLKSHETIQTWREY 110
            + A+R         R     + DYHTV             R +   +    T+ + R Y
Sbjct: 61  YRLALRL--------RTPGCLVEDYHTVQAPPVDRKARWATRREALAVAGLNTLVSRRAY 112

Query: 111 LCDASFTVALW-----LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPL 157
             D    V L       TP A      L  A+ +P + PYLGR+SCPL  PL
Sbjct: 113 RADPIVDVVLIHVDEGPTPEA------LATALRRPTFAPYLGRKSCPLGLPL 158


>UniRef50_Q2JWC5 CRISPR-associated protein Cas5, Ecoli subtype n=1 Tax=Synechococcus
           sp. JA-3-3Ab RepID=Q2JWC5_SYNJA
          Length = 207

 Score = 57.8 bits (138), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 49/162 (30%), Positives = 78/162 (48%), Gaps = 31/162 (19%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQR-DDTSSLQALSESVQF 63
           L++RL  PM +WG  +    R + R PT+S ++G+L A LG  R +    L AL   V  
Sbjct: 4   LLMRLRAPMMSWGDHSQFDYRDSRREPTKSAVIGILCAALGRPRWEPVDDLAALKMGV-- 61

Query: 64  AVRCDELILDDRRVSVTGL--RDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
                       RV+  G+  +D+HTV          +  ETI   R Y+ D  + V L 
Sbjct: 62  ------------RVNKEGILCKDFHTV----------QIKETISN-RYYVADGDYLVGLE 98

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQ 163
             P+   ++  L++A+ KP +  +LGR+S   + PL +G  +
Sbjct: 99  GDPN---LLRTLDQALQKPYWQVFLGRKSFIPSRPLRVGLVE 137


>UniRef50_D1CAJ0 CRISPR-associated protein Cas5 family n=1 Tax=Sphaerobacter
           thermophilus DSM 20745 RepID=D1CAJ0_SPHTD
          Length = 245

 Score = 57.4 bits (137), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 55/166 (33%), Positives = 77/166 (46%), Gaps = 24/166 (14%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
           S L+LRL GPMQAWG  +    R TG  P++SG++GLL A LG  R  ++ +  L+  ++
Sbjct: 2   STLLLRLTGPMQAWGTQSRFSWRDTGLEPSKSGVIGLLCAALGRPR--SAPVDDLAR-LR 58

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLG---------AREDYRGLKSHETIQTWREYLCD 113
             VR D           T   D+HT  G            D  G      I   R YL D
Sbjct: 59  MGVRVDR--------EGTMHVDFHTAGGWHRRAEAGYGVPDPSGTARRPQISR-RFYLAD 109

Query: 114 ASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFL 159
           A F V L        ++  L++A+  PR+  +LGR+S     P+ L
Sbjct: 110 ADFLVGL---EGDEELLVLLDRALAAPRWQLFLGRKSFVPAAPVRL 152


>UniRef50_B8FDI0 CRISPR-associated protein Cas5 family n=3 Tax=Bacteria
           RepID=B8FDI0_DESAA
          Length = 240

 Score = 55.1 bits (131), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 71/242 (29%), Positives = 102/242 (42%), Gaps = 33/242 (13%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
           YL++ L  P+Q+WG  +  G R T  FPTRSG+LGLL   LG   +    L  L+   Q 
Sbjct: 5   YLLMWLEAPLQSWGADSKFGRRDTLPFPTRSGVLGLLLCALGASGEQKELLARLAPYGQT 64

Query: 64  AVRCDELILDDRRVSVTG------LRDYHTVLGARED---YRGLKSHETIQ--------- 105
            + C          S         LRD+H V  A  D   +  L   +T +         
Sbjct: 65  VISCAGGRPGRSGGSPEKIPRQPLLRDFHMVGSAYNDKDPWERLHIPKTNEGKPAVGGGA 124

Query: 106 --TWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTC- 162
             T+R YL DA F V L L P    +  +  +A+  P +  YLGR++C  T  ++ G   
Sbjct: 125 KLTYRYYLQDARFAVILELPPD---LAEDFAQALQNPVWDIYLGRKNCAPTEFVYQGVFD 181

Query: 163 ---QASDPQKALLNYEPVGGDIYSEESVTGHH--LKFTARDEPMITLP-RQFASREWYVI 216
               A D   AL+  + +  D      V G H     T  D P+   P +++  R   VI
Sbjct: 182 SQKDAMDRAAALMEEKELMEDF---RVVDGEHPGEPITLNDVPLQFGPMKKYRDRRVTVI 238

Query: 217 KG 218
           + 
Sbjct: 239 RN 240


>UniRef50_B8HWH8 CRISPR-associated protein Cas5 family n=1 Tax=Cyanothece sp. PCC
           7425 RepID=B8HWH8_CYAP4
          Length = 216

 Score = 54.3 bits (129), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 49/157 (31%), Positives = 74/157 (47%), Gaps = 25/157 (15%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQR-DDTSSLQALSESVQF 63
           L+LR+  PM +WG  +    R + R PT+S ++GLL A LG  R +  + L AL   V  
Sbjct: 4   LLLRMRAPMMSWGDHSRFTIRDSRREPTKSAVIGLLCAALGRPRWEAVADLTALKMGV-- 61

Query: 64  AVRCDELILDDRRVSVTGLR--DYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
                       R++  GL   DYHTV  + +   G K + T+ + R Y+ DA + V   
Sbjct: 62  ------------RINQEGLVQCDYHTVQDSIKS-SGSKGN-TVISHRYYIADADYLVG-- 105

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRR----SCPLT 154
           L       +  L+ A+  P +  Y GR+    SCP+ 
Sbjct: 106 LEGSDRHFLESLDSALQSPIWQVYFGRKSFVPSCPVA 142


>UniRef50_B6XT64 Putative uncharacterized protein n=2 Tax=Bifidobacterium
           RepID=B6XT64_9BIFI
          Length = 212

 Score = 50.1 bits (118), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 29/70 (41%), Positives = 39/70 (55%), Gaps = 3/70 (4%)

Query: 106 TWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQAS 165
           T+R YL DA F VAL        V+  L++A+  P++  YLGRRSCP  +PL LG     
Sbjct: 58  TYRYYLADACFLVALGAD---RSVLEMLDEAIHSPKWPLYLGRRSCPPNYPLSLGIHDEY 114

Query: 166 DPQKALLNYE 175
           +  +  LN E
Sbjct: 115 EDIRQALNSE 124


>UniRef50_Q2RXJ5 CRISPR-associated protein, Cas5e family n=5 Tax=Proteobacteria
           RepID=Q2RXJ5_RHORT
          Length = 249

 Score = 49.7 bits (117), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 44/159 (27%), Positives = 69/159 (43%), Gaps = 5/159 (3%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
           +LI+ L  P+ A+G    +    T  FP  S L GL    LG +R +    Q L + + F
Sbjct: 6   WLIVHLEAPLLAFGGVAIDNVGVTRDFPAASMLTGLFANALGWRRTEWERHQRLQDRLIF 65

Query: 64  AVRCDE-----LILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV 118
           A R +      ++ D +   ++      T  G  E   G       +  R+Y  DAS  V
Sbjct: 66  AARRERENPTGVLTDTQNAKLSKTERGWTTWGEPEGRDGASYGAPHRRRRDYHGDASVVV 125

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPL 157
           AL L       + +L  A+ +P    ++GR+SC  + PL
Sbjct: 126 ALRLDAAEEPALDDLAAALDRPARPLFIGRKSCVPSRPL 164


>UniRef50_Q6NEQ9 Putative uncharacterized protein n=1 Tax=Corynebacterium
           diphtheriae RepID=Q6NEQ9_CORDI
          Length = 242

 Score = 48.9 bits (115), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 49/179 (27%), Positives = 77/179 (43%), Gaps = 24/179 (13%)

Query: 7   LRLAGPMQAWGQPTFEGT--RPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           +RL+GP+Q+W      G   R   R PT S L GLL   LG +R +  +     + V+F 
Sbjct: 7   IRLSGPLQSWAGSVVTGNIVRTEPR-PTFSSLRGLLAGALGARRGEWPNWL---DDVEFW 62

Query: 65  VRCD-ELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHE-------------TIQTWREY 110
           VR D + I+ +   ++  L +  T        +G K++              T    R Y
Sbjct: 63  VREDRKPIVVNEFQTINPLPEVETFRKRLLIAQGRKANSAKALTFTPDAQGGTSIVNRTY 122

Query: 111 LCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQK 169
           L D  + V +  + H    + E+E A   P +  YLGR++     P +LG   A   +K
Sbjct: 123 LADGEYLVRVTSSTH----MDEIENAFSSPAFVTYLGRKAFYAEFPFYLGRGSADAFEK 177


>UniRef50_C0W6U0 CRISPR-associated Cas5 family protein n=1 Tax=Actinomyces
           urogenitalis DSM 15434 RepID=C0W6U0_9ACTO
          Length = 201

 Score = 48.5 bits (114), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 43/128 (33%), Positives = 63/128 (49%), Gaps = 22/128 (17%)

Query: 39  LLGACLGIQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL 98
           +L A +G +R  T  ++ L  S++F VR D+          T LRD+HT        R L
Sbjct: 1   MLAAAVGRRR--TDPIEDLL-SLRFGVRKDQ--------PGTVLRDFHTA-------RTL 42

Query: 99  KSHETIQ-TWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPL 157
              +++  + R YL DA +  A+        ++  L+ AV  P +  YLGRRSCP + PL
Sbjct: 43  DGKQSMPLSERYYLADAVYLAAIE---GEKTLLEGLDVAVRHPVFPLYLGRRSCPPSQPL 99

Query: 158 FLGTCQAS 165
            LG   AS
Sbjct: 100 SLGIRHAS 107


>UniRef50_B8IJS9 CRISPR-associated protein Cas5 family n=1 Tax=Methylobacterium
           nodulans ORS 2060 RepID=B8IJS9_METNO
          Length = 253

 Score = 40.4 bits (93), Expect = 0.046,   Method: Compositional matrix adjust.
 Identities = 42/157 (26%), Positives = 69/157 (43%), Gaps = 6/157 (3%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           MR +L+L L  P+QAWG    +   P   FP  + + GL+   LG  R D   L+AL E 
Sbjct: 1   MREHLLLLLEAPLQAWGGVLVDAYGPVDEFPAATLVGGLVANALGYDRADWQRLEALQER 60

Query: 61  VQFA---VRCDELILDDRRVSV-TGLRDYHTVLGAREDYRGLKSHETI-QTWREYLCDAS 115
           +      +R    I D++   +  G   + T         G +++++  + +R+Y  D  
Sbjct: 61  LVVGAAVLRRGSTITDNQNAKLEKGDVGWTTRGRPEGRGGGAEAYKSPHRRFRDYHADTL 120

Query: 116 FTVALWLTPHATMV-ISELEKAVLKPRYTPYLGRRSC 151
             VAL L P      +  +   +  P    +LGR+ C
Sbjct: 121 ALVALRLDPEDEKPDLDAIAHTLEWPERPLFLGRKPC 157


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_Q46898 Uncharacterized protein ygcI n=13 Tax=Proteobact...   320   3e-86
UniRef50_Q314I4 CRISPR-associated protein, CT1976 n=1 Tax=Desulf...   213   4e-54
UniRef50_Q12YA8 CRISPR-associated protein, CT1976-like n=1 Tax=M...   205   7e-52
UniRef50_D1NTI1 CRISPR-associated protein Cas5 n=1 Tax=Bifidobac...   202   6e-51
UniRef50_D1CGD4 CRISPR-associated protein Cas5 family n=6 Tax=Ba...   197   2e-49
UniRef50_C2BET8 CRISPR-associated protein n=2 Tax=Firmicutes Rep...   197   2e-49
UniRef50_B7KJ26 CRISPR-associated protein Cas5 family n=1 Tax=Cy...   196   3e-49
UniRef50_C7MQD6 CRISPR-associated protein Cas5 n=1 Tax=Saccharom...   192   6e-48
UniRef50_Q04QB7 Putative uncharacterized protein n=2 Tax=Leptosp...   191   2e-47
UniRef50_A3EQA4 CRISPR-ssociated protein, Cas5 n=3 Tax=Bacteria ...   190   2e-47
UniRef50_Q1R114 CRISPR-associated protein, CT1976 n=1 Tax=Chromo...   189   7e-47
UniRef50_Q0W584 Putative uncharacterized protein n=1 Tax=uncultu...   187   3e-46
UniRef50_C5SD48 CRISPR-associated protein Cas5 family n=1 Tax=Al...   187   3e-46
UniRef50_Q2RY19 CRISPR-associated protein, Cas5e family n=1 Tax=...   186   4e-46
UniRef50_D2RB02 CRISPR system CASCADE complex protein CasD n=3 T...   186   4e-46
UniRef50_B0S4B6 Putative uncharacterized protein n=1 Tax=Finegol...   185   1e-45
UniRef50_B0TDU1 Crispr-associated protein cas5 n=1 Tax=Heliobact...   183   4e-45
UniRef50_C8XAY4 CRISPR-associated protein Cas5 family n=2 Tax=Ac...   182   6e-45
UniRef50_A1SV73 CRISPR-associated protein, Cas5e family n=2 Tax=...   182   1e-44
UniRef50_A8LYZ7 CRISPR-associated protein Cas5 family n=2 Tax=Ac...   181   2e-44
UniRef50_D1Y486 Crispr-associated protein Cas5 n=1 Tax=Pyramidob...   181   2e-44
UniRef50_D0WFC8 CRISPR-associated protein Cas5 n=1 Tax=Slackia e...   180   2e-44
UniRef50_B4S8P8 CRISPR-associated protein Cas5 family n=8 Tax=Ba...   180   3e-44
UniRef50_Q1EQS9 CRISPR-associated protein n=3 Tax=Streptomyces R...   180   4e-44
UniRef50_A5UR14 CRISPR-associated protein, Cas5e family n=1 Tax=...   179   6e-44
UniRef50_C9M2Y8 CRISPR-associated protein n=1 Tax=Lactobacillus ...   179   7e-44
UniRef50_D0Y918 CRISPR-associated protein Cas5 family n=2 Tax=De...   179   7e-44
UniRef50_A5GBK2 CRISPR-associated protein Cas5 family n=2 Tax=De...   178   1e-43
UniRef50_C7MTB0 CRISPR-associated protein Cas5 n=1 Tax=Saccharom...   178   1e-43
UniRef50_D1A6Q5 CRISPR-associated protein Cas5 family n=2 Tax=Ac...   178   2e-43
UniRef50_A8ZZ17 CRISPR-associated protein Cas5 family n=1 Tax=De...   177   2e-43
UniRef50_A8SDR7 Putative uncharacterized protein n=1 Tax=Faecali...   177   2e-43
UniRef50_A7BA63 Putative uncharacterized protein n=1 Tax=Actinom...   177   3e-43
UniRef50_A6W168 CRISPR-associated protein Cas5 family n=6 Tax=Ga...   176   5e-43
UniRef50_B8HWH8 CRISPR-associated protein Cas5 family n=1 Tax=Cy...   176   6e-43
UniRef50_B1VIY0 CRISPR-associated protein n=9 Tax=Actinomycetale...   175   7e-43
UniRef50_B3E5U9 CRISPR-associated protein Cas5 family n=2 Tax=De...   175   1e-42
UniRef50_A1ARH6 CRISPR-associated protein, Cas5e family n=2 Tax=...   175   1e-42
UniRef50_UPI0001AF1D4C CRISPR-associated protein, CT1976 n=1 Tax...   174   2e-42
UniRef50_D2L2X8 CRISPR-associated protein Cas5 family n=1 Tax=De...   174   2e-42
UniRef50_C9M9R7 CRISPR-associated protein Cas5, Ecoli subtype n=...   174   2e-42
UniRef50_Q5YRB6 Putative uncharacterized protein n=1 Tax=Nocardi...   172   9e-42
UniRef50_B2GBJ9 Putative uncharacterized protein n=1 Tax=Lactoba...   172   1e-41
UniRef50_Q2JWC5 CRISPR-associated protein Cas5, Ecoli subtype n=...   170   4e-41
UniRef50_Q47PI7 CRISPR-associated protein, Cas5e family n=12 Tax...   169   6e-41
UniRef50_Q2JH27 CRISPR-associated protein, CT1976 n=6 Tax=Actino...   167   2e-40
UniRef50_B4UE71 CRISPR-associated protein Cas5 family n=2 Tax=An...   167   2e-40
UniRef50_B8IZA7 CRISPR-associated protein Cas5 family n=1 Tax=De...   166   4e-40
UniRef50_C7LYW6 CRISPR-associated protein Cas5 family n=1 Tax=Ac...   165   1e-39
UniRef50_Q03C60 CRISPR-associated protein n=4 Tax=Lactobacillus ...   163   4e-39
UniRef50_B8FDI0 CRISPR-associated protein Cas5 family n=3 Tax=Ba...   163   4e-39
UniRef50_A8M404 CRISPR-associated protein Cas5 family n=1 Tax=Sa...   163   4e-39
UniRef50_D0MET6 CRISPR-associated protein Cas5 family n=1 Tax=Rh...   162   8e-39
UniRef50_B8GIV3 CRISPR-associated protein Cas5 family n=1 Tax=Me...   162   9e-39
UniRef50_D1CAJ0 CRISPR-associated protein Cas5 family n=1 Tax=Sp...   160   4e-38
UniRef50_Q1J367 CRISPR-associated protein, CT1976 n=1 Tax=Deinoc...   159   8e-38
UniRef50_Q0AA33 CRISPR-associated protein Cas5 family n=2 Tax=Ga...   159   9e-38
UniRef50_Q2FNU0 CRISPR-associated protein, CT1976 n=1 Tax=Methan...   153   5e-36
UniRef50_B4TTX2 CRISPR-associated protein Cas5 n=15 Tax=Enteroba...   152   8e-36
UniRef50_A9HLC6 CRISPR-associated protein Cas5 family n=11 Tax=A...   151   2e-35
UniRef50_Q0BSC7 Putative uncharacterized protein n=1 Tax=Granuli...   148   1e-34
UniRef50_UPI0001B51C2B CRISPR-associated Cas5 family protein n=1...   148   2e-34
UniRef50_B8IMR2 CRISPR-associated protein Cas5 family n=1 Tax=Me...   143   4e-33
UniRef50_C5V9N1 CRISPR-associated protein Cas5 n=1 Tax=Corynebac...   141   2e-32
UniRef50_B6B783 CRISPR-associated protein Cas5, Ecoli subtype n=...   141   2e-32
UniRef50_C2KP44 Putative uncharacterized protein n=1 Tax=Mobilun...   137   2e-31
UniRef50_B6IWM3 CRISPR-associated protein, CT1976 family n=1 Tax...   137   3e-31
UniRef50_B5GY62 Crispr-associated protein (Fragment) n=1 Tax=Str...   135   9e-31
UniRef50_C2GEY8 CRISPR-associated protein n=1 Tax=Corynebacteriu...   132   1e-29
UniRef50_Q2RXJ5 CRISPR-associated protein, Cas5e family n=5 Tax=...   132   1e-29
UniRef50_B5F422 CRISPR-associated protein Cas5 n=59 Tax=Enteroba...   130   3e-29
UniRef50_Q6NEQ9 Putative uncharacterized protein n=1 Tax=Coryneb...   129   8e-29
UniRef50_C0W6U0 CRISPR-associated Cas5 family protein n=1 Tax=Ac...   122   1e-26
UniRef50_B6XT64 Putative uncharacterized protein n=2 Tax=Bifidob...   119   8e-26

Sequences not found previously or not previously below threshold:

UniRef50_B8IJS9 CRISPR-associated protein Cas5 family n=1 Tax=Me...   107   3e-22
UniRef50_A0LM54 Putative uncharacterized protein n=1 Tax=Syntrop...    84   4e-15
UniRef50_UPI0000F51765 hypothetical protein Faci_00030 n=1 Tax=F...    55   2e-06
UniRef50_B1I5P1 CRISPR-associated protein Cas5 n=2 Tax=Clostridi...    50   6e-05
UniRef50_Q3AA65 CRISPR-associated protein Cas5, Hmari subtype n=...    49   1e-04
UniRef50_B5IGN1 CRISPR-associated protein Cas5 n=1 Tax=Acidulipr...    49   1e-04
UniRef50_B0K553 CRISPR-associated protein Cas5, Hmari subtype n=...    47   3e-04
UniRef50_Q1AZD3 CRISPR-associated protein, Cas5h family n=1 Tax=...    46   9e-04
UniRef50_D1N0K0 Putative uncharacterized protein n=1 Tax=Victiva...    46   0.001
UniRef50_A3DHS3 CRISPR-associated protein Cas5 n=3 Tax=Clostridi...    45   0.003
UniRef50_D0MJ68 CRISPR-associated protein Cas5 n=1 Tax=Rhodother...    44   0.004
UniRef50_C9RCY2 CRISPR-associated protein Cas5, Hmari subtype n=...    42   0.015
UniRef50_A5D0Y3 Putative uncharacterized protein n=1 Tax=Pelotom...    42   0.021
UniRef50_D1A6P6 Metal dependent phosphohydrolase n=1 Tax=Thermom...    41   0.038

>UniRef50_Q46898 Uncharacterized protein ygcI n=13 Tax=Proteobacteria
           RepID=YGCI_ECOLI
          Length = 224

 Score =  320 bits (819), Expect = 3e-86,   Method: Composition-based stats.
 Identities = 224/224 (100%), Positives = 224/224 (100%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES
Sbjct: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL
Sbjct: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180
           WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD
Sbjct: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180

Query: 181 IYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVSQ 224
           IYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVSQ
Sbjct: 181 IYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVSQ 224


>UniRef50_Q314I4 CRISPR-associated protein, CT1976 n=1 Tax=Desulfovibrio
           desulfuricans subsp. desulfuricans str. G20
           RepID=Q314I4_DESDG
          Length = 245

 Score =  213 bits (542), Expect = 4e-54,   Method: Composition-based stats.
 Identities = 83/246 (33%), Positives = 111/246 (45%), Gaps = 33/246 (13%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M  YL  ++ GP+QA+G       RPT   PTRS +LG+L A +GI+RD+ + L  L + 
Sbjct: 1   MAQYLTFQIYGPLQAYGTVAVGEIRPTSTMPTRSAVLGILAAAIGIRRDEETRLAELRDG 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGA----------REDYRGLKSHETIQTWREY 110
            + AVR D             + DYHT+             R D   L    TI + REY
Sbjct: 61  YRVAVRED--------APGKVMLDYHTIQTPGARGKRQLHCRRDELLLTEPNTILSRREY 112

Query: 111 LCDASFTVALWLTPHA-TMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQK 169
           L DA FTV LW   H     + E+ +A+  PR+T  LGR+SCP   P        + PQ+
Sbjct: 113 LMDALFTVCLWQANHTVPYSLQEIARALRSPRWTIGLGRKSCPPALPFAPKITDHTTPQE 172

Query: 170 ALLNYEP---VGGDIYSEE------SVTGHH--LKFTARDEPMITLPRQFAS---REWYV 215
           A+  Y     V   + S +         G H   + T RD P+    RQFA    RE  V
Sbjct: 173 AVAAYPADKLVSAGLRSPQVMRMLLDTEGPHTDTETTVRDVPLHHGRRQFAERKVRELLV 232

Query: 216 IKGGMD 221
            K   D
Sbjct: 233 RKAATD 238


>UniRef50_Q12YA8 CRISPR-associated protein, CT1976-like n=1 Tax=Methanococcoides
           burtonii DSM 6242 RepID=Q12YA8_METBU
          Length = 244

 Score =  205 bits (522), Expect = 7e-52,   Method: Composition-based stats.
 Identities = 65/244 (26%), Positives = 104/244 (42%), Gaps = 38/244 (15%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M+ YLI RL GPM +WG       RPT   P++S + GL+ A LGI+RD+      LS +
Sbjct: 1   MKEYLIFRLYGPMASWGDIAVGQHRPTYDHPSKSAIFGLIAAALGIRRDEEERHLELSNA 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVL-------------GAREDYRGLKSHE--TIQ 105
             +              +   LRDYHT                 R+D   +   E  T+ 
Sbjct: 61  YSYGTLI--------NSAGKLLRDYHTSQVPSAGTGRNRKTFATRKDELAVPKEELNTVL 112

Query: 106 TWREYLCDASFTVALWLTPH-ATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQA 164
           + R+Y CD  +TV L          +  L  ++ +P +  YLGR+SCPL  P+      A
Sbjct: 113 STRDYYCDGVYTVILSCKTDTPPYSLELLGNSLKEPSFCLYLGRKSCPLALPINPKIVSA 172

Query: 165 SDPQKALLNYEPVGGDIYSEESVTGHH-------------LKFTARDEPMITLPR-QFAS 210
           S+ ++AL + +P    +  +  +   +                 +R + +++  R QF+ 
Sbjct: 173 SNIKEALQSVDPGEEGLVKKIEMKSPYRLYWDDPKESMTCEHTISRYDKLLSRKRWQFSK 232

Query: 211 REWY 214
           R  Y
Sbjct: 233 RNEY 236


>UniRef50_D1NTI1 CRISPR-associated protein Cas5 n=1 Tax=Bifidobacterium gallicum DSM
           20093 RepID=D1NTI1_9BIFI
          Length = 250

 Score =  202 bits (515), Expect = 6e-51,   Method: Composition-based stats.
 Identities = 66/226 (29%), Positives = 101/226 (44%), Gaps = 28/226 (12%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            S LILRLAGPMQ+WG  +    R T   PT+S ++GLL +  G +R+D  S++ L   +
Sbjct: 1   MSVLILRLAGPMQSWGDSSRFNRRETRTEPTKSAVIGLLASAQGRRRED--SIEDLL-GL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +F VR D+            +RD+ T         G  S     T R YL DA F VA+ 
Sbjct: 58  RFGVRSDQ--------PGRIMRDFQTEKSIARKKSGEFSLTMPLTHRYYLADAKFLVAIE 109

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                  ++  L+ A+  P++  +LGRRSCP   P+ LG    ++ ++AL     +    
Sbjct: 110 ---GERSLLESLDAALRNPQWPLFLGRRSCPPASPVSLGVKDYANVEEALDKEPWIASPW 166

Query: 182 YSE------------ESVTGHHLKFTARDEPMITL--PRQFASREW 213
           Y +            ++V          D P+      R++A R  
Sbjct: 167 YRKKVHDSKRLQVVVDAVENGETTGQQSDMPLSFSQKHRRYAQRPV 212


>UniRef50_D1CGD4 CRISPR-associated protein Cas5 family n=6 Tax=Bacteria
           RepID=D1CGD4_THET1
          Length = 230

 Score =  197 bits (501), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 69/227 (30%), Positives = 107/227 (47%), Gaps = 26/227 (11%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M + L++RL+GPMQ+WG  +    R TGR P++SG++GL+ A LG  R  T+ +  L   
Sbjct: 1   MPT-LLMRLSGPMQSWGTQSRFTVRDTGREPSKSGVIGLICAALGRPR--TAPVDDLVR- 56

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHET-----IQTWREYLCDAS 115
           ++  VR D             +RDYHT  GA    R   +  T     +Q+ R YL DAS
Sbjct: 57  LRMGVRVDR--------EGIVMRDYHTAGGAPAGERYGVATVTGDQRPVQSSRYYLADAS 108

Query: 116 FTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGT-------CQASDPQ 168
           F VAL        ++ ++++A+  PR+  +LGR+SC  + P+ L          +  D +
Sbjct: 109 FLVALEGGEEDRPLLEQIDEALRAPRWQLFLGRKSCVPSEPIHLPKEPPLGPPIREEDLR 168

Query: 169 KALLNYEPVGGDIYSEESVTGHHLKFTARDEP--MITLPRQFASREW 213
            AL++Y    G             +    D P       RQ+A+R  
Sbjct: 169 TALISYPWPEGAHRLRFVFEDPEGEELRNDVPISFEIGNRQYAARFV 215


>UniRef50_C2BET8 CRISPR-associated protein n=2 Tax=Firmicutes RepID=C2BET8_9FIRM
          Length = 244

 Score =  197 bits (501), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 62/223 (27%), Positives = 103/223 (46%), Gaps = 29/223 (13%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
             ++L+L GPMQ+WG  +   TR +  +P++SG++G++ A  G +RD+   +Q L++ + 
Sbjct: 5   KTILLKLTGPMQSWGTSSRFETRTSDYYPSKSGVIGIIAASFGYERDEDEKIQKLND-LD 63

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWL 122
           FAVR D+             +DYH    AR+     +   T  T R Y+ DA F VA+  
Sbjct: 64  FAVRVDQ--------EGVLKKDYHI---ARKVKPNGELERTYVTNRYYMEDAVFVVAI-- 110

Query: 123 TPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDIY 182
           +      + E+ + +  P + P++GRRSCPL     LGT +   P +AL N +    D +
Sbjct: 111 SHEDDKWMEEILQGLKYPYFQPFMGRRSCPLPARFILGTNE-EGPIEALENLDWQAADWF 169

Query: 183 SEESV--------------TGHHLKFTARDEPMITLPRQFASR 211
            +++                  H     R        R+F  R
Sbjct: 170 KKKNKNYRADIYADKDLLPENSHTIRNDRVVSFSQKERKFGPR 212


>UniRef50_B7KJ26 CRISPR-associated protein Cas5 family n=1 Tax=Cyanothece sp. PCC
           7424 RepID=B7KJ26_CYAP7
          Length = 215

 Score =  196 bits (499), Expect = 3e-49,   Method: Composition-based stats.
 Identities = 68/228 (29%), Positives = 113/228 (49%), Gaps = 17/228 (7%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M   L+LRLAGP+Q+WG+ +    R T   PT+SG++GL+ A +GI RD+   L  L++ 
Sbjct: 1   MMKTLLLRLAGPLQSWGRGSRFDFRDTDTIPTKSGVIGLVAAAMGINRDNQVELAKLAQ- 59

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           ++  V  ++            + DYHTV+G      G      IQ++R+YLC+A F V L
Sbjct: 60  LRMGVCVEK--------EGKLVVDYHTVIGTIH-ADGKPHKAPIQSYRQYLCNAEFLVGL 110

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNY--EPVG 178
             + +   +++E+E  +  P++  +LGR++CP + P+F+     S  + AL  Y    + 
Sbjct: 111 ESSEY--HLLNEIEHYLCFPKWELFLGRKACPPSKPIFVDLLTNS-LEDALYQYAISHLK 167

Query: 179 GDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIK--GGMDVSQ 224
              Y     +         D P+    R F++R     K     DVS+
Sbjct: 168 KGTYRLLIESKEPTGALRLDVPIDFKKRIFSARTVITPKPLEVSDVSE 215


>UniRef50_C7MQD6 CRISPR-associated protein Cas5 n=1 Tax=Saccharomonospora viridis
           DSM 43017 RepID=C7MQD6_SACVD
          Length = 236

 Score =  192 bits (489), Expect = 6e-48,   Method: Composition-based stats.
 Identities = 73/220 (33%), Positives = 107/220 (48%), Gaps = 22/220 (10%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+L L GPMQAWG  +    R T  +PTRSG++G++ A LG Q  D  SL  LS  +
Sbjct: 1   MTTLVLHLDGPMQAWGHASQWDHRDTLDYPTRSGVIGMIAAALGKQWGD--SLDDLSP-L 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDY----RGLKSHETIQTWREYLCDASFT 117
           +F +R D             + DYHT  G  E      +G      + + R Y+ DA++T
Sbjct: 58  RFTIRIDR--------PGRRIVDYHTAGGGYEVGIARVKGGNRAHAVLSDRFYMSDAAYT 109

Query: 118 VALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNY--E 175
           VA+        ++  ++ A+  P + P+LGRRSCP   P  LG     DP + L  +  +
Sbjct: 110 VAIT---GPDTLLYRVDDALRAPVFGPFLGRRSCPPAGPWHLGLHDG-DPLRTLPLHRDK 165

Query: 176 PVGGDIYSEESVTGHHLKF-TARDEPMITLPRQFASREWY 214
           P  GD  + E V+ H     T R +  +T P +F  R  Y
Sbjct: 166 PRDGDTVAVEFVSDHETHGPTDRVDTTLTDPHEFGPRRSY 205


>UniRef50_Q04QB7 Putative uncharacterized protein n=2 Tax=Leptospira borgpetersenii
           serovar Hardjo-bovis RepID=Q04QB7_LEPBJ
          Length = 247

 Score =  191 bits (485), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 61/220 (27%), Positives = 93/220 (42%), Gaps = 18/220 (8%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M+ YL+ RL GP+ +WG       RP+  FPT+S ++GL+ A  G  R +   +  L +S
Sbjct: 1   MKDYLVFRLYGPLVSWGNIAVGEYRPSDSFPTKSAIIGLISASFGFDRSEDGKISELVKS 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSH----------ETIQTWREY 110
           V FA +               LRDYHT+       R L +           ETI + R+Y
Sbjct: 61  VFFATKTLN--------PGNLLRDYHTIQSPGNVKRSLLTRKDELLDSEYVETILSSRDY 112

Query: 111 LCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKA 170
             DA + VAL     A   + E+  A+L P +TPYLGR+SC +  P+      +     A
Sbjct: 113 RVDAVYDVALSEKKRAPYSLKEIRNALLSPIHTPYLGRKSCSIALPMCPEILSSDSFPNA 172

Query: 171 LLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFAS 210
              Y  +    Y            +++   ++ L      
Sbjct: 173 FEEYNKILMKKYESSDYKDPLADLSSKSSAILYLWEDPTE 212


>UniRef50_A3EQA4 CRISPR-ssociated protein, Cas5 n=3 Tax=Bacteria RepID=A3EQA4_9BACT
          Length = 227

 Score =  190 bits (484), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 61/223 (27%), Positives = 96/223 (43%), Gaps = 23/223 (10%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M + L++RL  PMQ+WG  +    R TG+ P++SG++GLL A LGI R++   L+ L+  
Sbjct: 1   MPT-LLIRLVSPMQSWGTSSRFDQRDTGKEPSKSGVIGLLAAALGIDRNNWDDLEPLA-G 58

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           +   VR D              RDY T           K H T  T+REYL DA F V  
Sbjct: 59  LSMGVRHDR--------PGIPRRDYQTASKII-SADHSKIHPTAVTYREYLADAVFLVGF 109

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180
                   ++ ++  A+  P +  +LGR+S   + P+++     + P +  L + P    
Sbjct: 110 E--SAEVSLLEKINSALKNPVWPLFLGRKSYVPSEPIWIENGLKNVPLREALEHFPWIAC 167

Query: 181 IYSEESVTGHH---------LKFTARDEPM-ITLPRQFASREW 213
               E +                   D+P+     R+F SR  
Sbjct: 168 RRRNERLPEKLVITFESEDGTGVLKMDQPLSSFAKRRFGSRFV 210


>UniRef50_Q1R114 CRISPR-associated protein, CT1976 n=1 Tax=Chromohalobacter
           salexigens DSM 3043 RepID=Q1R114_CHRSD
          Length = 260

 Score =  189 bits (480), Expect = 7e-47,   Method: Composition-based stats.
 Identities = 66/183 (36%), Positives = 92/183 (50%), Gaps = 20/183 (10%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M  +L+ RL  PM +WG+      RPT  +P R  +LGL+GA LGI+RDD      L +S
Sbjct: 1   MTGHLVFRLYAPMASWGEAAVGEARPTATYPGRGAILGLIGAALGIRRDDDEGQLRLRQS 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYR------------GLKSHETIQTWR 108
           +  AV+        +R     LRDYHTV       +               +  TI + R
Sbjct: 61  LGIAVK--------QRSPGWLLRDYHTVQVPPSQSKVNYRSRREELSVPKDALNTILSSR 112

Query: 109 EYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQ 168
           +Y CD  + VAL L P A   + EL+ A+ +PR+T YLGR++CPL  PL     +A   +
Sbjct: 113 DYRCDGLWVVALRLMPDAVWTLDELKSALERPRFTLYLGRKACPLAAPLTPAIVEADHWR 172

Query: 169 KAL 171
            AL
Sbjct: 173 GAL 175


>UniRef50_Q0W584 Putative uncharacterized protein n=1 Tax=uncultured methanogenic
           archaeon RC-I RepID=Q0W584_UNCMA
          Length = 227

 Score =  187 bits (474), Expect = 3e-46,   Method: Composition-based stats.
 Identities = 57/178 (32%), Positives = 83/178 (46%), Gaps = 12/178 (6%)

Query: 10  AGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDE 69
            GPMQ+WG       R TG  PT+SG++GLLG  LG  R D      L   ++  +R + 
Sbjct: 12  EGPMQSWGLKARWDIRDTGDEPTKSGIIGLLGCALGYARKDPRLTDELDSQLRIGIRVE- 70

Query: 70  LILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPHATMV 129
                        RDYHTV G      G     TI ++R+YL DA+F V L        +
Sbjct: 71  -------CPGEIARDYHTVSGELRTAEGKLRETTIVSFRDYLQDAAFLVVLE---GPGEL 120

Query: 130 ISELEKAVLKPRYTPYLGRRSCPLTHPLFLG-TCQASDPQKALLNYEPVGGDIYSEES 186
           ++ +  A+  P +  YLGR+SCP T P+F   T   +    AL  +    G + + ++
Sbjct: 121 LTRISNALKDPVWPIYLGRKSCPPTRPVFETLTTDYASIDDALSRHPWSSGTMEARKA 178


>UniRef50_C5SD48 CRISPR-associated protein Cas5 family n=1 Tax=Allochromatium
           vinosum DSM 180 RepID=C5SD48_CHRVI
          Length = 227

 Score =  187 bits (474), Expect = 3e-46,   Method: Composition-based stats.
 Identities = 108/224 (48%), Positives = 134/224 (59%), Gaps = 9/224 (4%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M SYLILRL GPMQAWG  TFE  RP+  FPTRSGLLGLLGACLG+ R DT SL AL+ES
Sbjct: 1   MPSYLILRLDGPMQAWGTHTFEDYRPSNPFPTRSGLLGLLGACLGLDRSDTPSLDALAES 60

Query: 61  VQFAVRCDELILDDR-----RVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDAS 115
           V F VR D                T L DYHTVL AR+   G  +   IQ+ REYL DA+
Sbjct: 61  VAFTVRLDTGAPRPGVDRLMPKRHTKLSDYHTVLDARK-VDGSTNKFPIQSHREYLFDAA 119

Query: 116 FTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPL--FLGTCQASDPQKALLN 173
           F VA+   P A+  ++ + +++ +PR+TP LGRRSCPL  PL       +A D + AL  
Sbjct: 120 FAVAIGSRPDASFSLARIAESLRQPRFTPVLGRRSCPLGRPLLERPDCIEADDAKAALAQ 179

Query: 174 YEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIK 217
           + P GG IYSE+ +      +  RD P     RQFA+R  Y+ +
Sbjct: 180 FPPHGGLIYSEDELVSDQPTWI-RDVPRYGRHRQFATRRLYLHR 222


>UniRef50_Q2RY19 CRISPR-associated protein, Cas5e family n=1 Tax=Rhodospirillum
           rubrum ATCC 11170 RepID=Q2RY19_RHORT
          Length = 261

 Score =  186 bits (473), Expect = 4e-46,   Method: Composition-based stats.
 Identities = 74/234 (31%), Positives = 102/234 (43%), Gaps = 32/234 (13%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           +R +L+ RL GPM AWG       R T   P +S +LGLL A LGI R D ++ +AL   
Sbjct: 3   VRDFLVFRLVGPMAAWGDIAVGERRGTWDVPAKSAILGLLAAGLGIDRADRTAHEALDRG 62

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTV----------LGAREDYRGLKSHETIQTWREY 110
           + FAVR D             LRDYHT              R D        T+ + R Y
Sbjct: 63  LGFAVRQDR--------PGRLLRDYHTAQAPKARKNARWSTRRDELNDDDLNTVLSDRLY 114

Query: 111 LCDASFTVALWLTPH-ATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQK 169
             +A  T A+W         + +L +A+L+PR+TPYLGR++CPL  P      QA     
Sbjct: 115 RTNAIATPAIWRRQGTEGPTLDQLTQALLRPRFTPYLGRKACPLGWPPRPRLLQADGLLA 174

Query: 170 ALLNYEPVGGDIYSE--ESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMD 221
           A   Y+    D   +  ++  G     T R  P+           W+ I  G+D
Sbjct: 175 AFDAYDSAEWDAARQFHKAYPGGWPGDTDRPTPV-----------WFEIAAGLD 217


>UniRef50_D2RB02 CRISPR system CASCADE complex protein CasD n=3 Tax=Actinobacteria
           (class) RepID=D2RB02_GARVA
          Length = 291

 Score =  186 bits (473), Expect = 4e-46,   Method: Composition-based stats.
 Identities = 55/187 (29%), Positives = 89/187 (47%), Gaps = 18/187 (9%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQR--DDTSSLQALS 58
           M+S L+L+ +GP+Q+WG  +   TR T  +P++S ++G++ A  G +R  D   ++  L+
Sbjct: 1   MKS-LLLKFSGPLQSWGTDSHFETRHTDYYPSKSAVIGMIAAAFGYRRSTDCDENIAKLN 59

Query: 59  ESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV 118
           + + FAVR D+            LRDYH     +         +   T R YL DA F V
Sbjct: 60  D-LDFAVRIDQ--------QGNLLRDYHIAAKYK---ANGDFEKNYVTNRYYLEDAIFLV 107

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVG 178
           A+    +   +I ++  A+  P +   LGRRS P T    LG        +ALL +E + 
Sbjct: 108 AI--GSNNEQLIYDISNALRSPYFQSSLGRRSLPPTADFILGVEDC-GVIQALLTHEWLA 164

Query: 179 GDIYSEE 185
                + 
Sbjct: 165 NKWSKKR 171


>UniRef50_B0S4B6 Putative uncharacterized protein n=1 Tax=Finegoldia magna ATCC
           29328 RepID=B0S4B6_FINM2
          Length = 228

 Score =  185 bits (470), Expect = 1e-45,   Method: Composition-based stats.
 Identities = 63/238 (26%), Positives = 107/238 (44%), Gaps = 31/238 (13%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            S ++L+ A P+Q+WG       R T  +PT+S ++GL+ A  G ++ DT S++ L+ S+
Sbjct: 1   MSVILLKFASPLQSWGGLANYEIRNTEYYPTKSAVIGLVAAAFGYKKTDTESIKRLN-SL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTW---REYLCDASFTV 118
            F+VR D+          + +RD+   +     Y     +  +++    + Y+ DA F +
Sbjct: 60  NFSVRIDQ--------KGSLIRDFQIAMEYNPKYMPNDPNYFVKSNLIQKYYIQDAKFLI 111

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQ-------------AS 165
           AL  +     ++ ++  A+  P Y  +LGR+S P+     +G                AS
Sbjct: 112 AL--SSDDETLMEDVYNALESPAYQLFLGRKSNPINADYLIGKFDGNELEIIKDYEWLAS 169

Query: 166 DPQKALLNYEPVGGDIYSEESVTGHHLKFTARD--EPMITLPRQFASR--EWYVIKGG 219
              K  +  + V   I+S+   TG   K   RD  E      R F+SR    YV K G
Sbjct: 170 KWYKKSIKKDSVELSIFSDYIDTGSKEKLIRRDLTESFENTKRDFSSRFEYRYVTKVG 227


>UniRef50_B0TDU1 Crispr-associated protein cas5 n=1 Tax=Heliobacterium modesticaldum
           Ice1 RepID=B0TDU1_HELMI
          Length = 230

 Score =  183 bits (464), Expect = 4e-45,   Method: Composition-based stats.
 Identities = 67/228 (29%), Positives = 102/228 (44%), Gaps = 23/228 (10%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           L LRL GP+Q+WG  +    R +   PT+SG++GLLG  LG  R+D   L++L  +++  
Sbjct: 6   LALRLEGPLQSWGSRSRWDYRDSALEPTKSGIIGLLGCALGWSRND-KRLESLDAALRLT 64

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHE-----TIQTWREYLCDASFTVA 119
           VR D+          T L D+HTV G      G +        T+ + R YL +ASF   
Sbjct: 65  VRIDK--------PGTPLIDFHTVQGYLLMAEGKQKKSGNDMYTVVSRRVYLQEASFLAL 116

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQAS--DPQKALLNYE-- 175
           L     A   + + +KA+  P +  +LGR+SCP   PLF    +    D  +A+ +    
Sbjct: 117 LTGEQGA---LHQCKKALNDPVWPVFLGRKSCPPARPLFDSFYEGDFRDVLEAMRSIPWS 173

Query: 176 --PVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMD 221
             P  G I     +     +   +D   I   R +  R   V    +D
Sbjct: 174 SAPAAGPIRLRYVMEDEGGREWRQDVLRINGARMYGRRRVSVGWVDLD 221


>UniRef50_C8XAY4 CRISPR-associated protein Cas5 family n=2 Tax=Actinomycetales
           RepID=C8XAY4_NAKMY
          Length = 252

 Score =  182 bits (463), Expect = 6e-45,   Method: Composition-based stats.
 Identities = 70/211 (33%), Positives = 96/211 (45%), Gaps = 22/211 (10%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            S L+LRL GPMQ+WG+ +    R T   P++S ++GLL A LG +R D  +++ L+  +
Sbjct: 1   MSVLVLRLTGPMQSWGERSRYARRETAAEPSKSAIVGLLAAALGRRRTD--AIEDLA-GL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETI-QTWREYLCDASFTVAL 120
            F VR D+          T LRD+ T        R L    T+  + R YL DA F  A+
Sbjct: 58  IFGVRVDQ--------PGTLLRDFQTA-------RSLDGARTMPLSERYYLSDARFLAAV 102

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180
                   +I+ L  A+  P +  YLGRRSCP + P+    C  S P  A L  EP    
Sbjct: 103 E---GPESLIAGLAGALRDPTFPLYLGRRSCPPSEPIAQQDCIRSGPLLAALFDEPWHAT 159

Query: 181 IYSEESVTGHHLKFTARDEPMITLPRQFASR 211
                 V        A D     +P Q A R
Sbjct: 160 KSYRRRVADPARLSIAVDAAATEVPAQLAER 190


>UniRef50_A1SV73 CRISPR-associated protein, Cas5e family n=2 Tax=Gammaproteobacteria
           RepID=A1SV73_PSYIN
          Length = 217

 Score =  182 bits (461), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 78/214 (36%), Positives = 110/214 (51%), Gaps = 15/214 (7%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              LIL+  G M A+G  TF+  R    FPTRS ++G+LGA +GI R++ + L ALSE +
Sbjct: 1   MKTLILKTEG-MSAYGLQTFDVHRRANHFPTRSAIMGILGAAMGITRENFNELYALSEQL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           + AV+          +S   + DYHTV   R   +G        T+REY CD+  T A+ 
Sbjct: 60  KIAVQV--------NLSGEKMVDYHTVQHFRSP-QGKIQKGVKPTYREYWCDSEHTFAIS 110

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
              H   VI +L  +V  P +T + GR+SCPLT PLF       +P  AL N+    G I
Sbjct: 111 AAEH---VIEKLVNSVKFPEFTLFQGRKSCPLTRPLFEAVTDDDNPANALKNHGE-QGQI 166

Query: 182 YSEESVTGHHLKFTARDEPMITLPRQFASREWYV 215
           +S+ S          RD  +  +PR++A R  YV
Sbjct: 167 FSDISGDNQLAIVQVRD-LITAIPRKYAMRTVYV 199


>UniRef50_A8LYZ7 CRISPR-associated protein Cas5 family n=2 Tax=Actinomycetales
           RepID=A8LYZ7_SALAI
          Length = 257

 Score =  181 bits (459), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 78/240 (32%), Positives = 109/240 (45%), Gaps = 43/240 (17%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           L+LRLAGPMQ+WG  +    R TG  PTRS ++G++ A  G  R +   L  L+  VQF 
Sbjct: 4   LLLRLAGPMQSWGDHSTFSVRDTGTVPTRSAMIGIIAAAQGRHRGE--PLGDLAP-VQFT 60

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHE---------TIQTWREYLCDAS 115
           VR D           T + D+HTV G     R + + E         TI + R YL DA 
Sbjct: 61  VRVDR--------PGTVMSDFHTVGGGAPPERTVPTAEGKRRTAGAGTIVSRRFYLADAV 112

Query: 116 FTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKAL---- 171
           FTVA+        ++ ++  A+  P + PYLGRRSCP+ HP  L +    DP   L    
Sbjct: 113 FTVAVTGPDD---LVGQIHTALNNPVWGPYLGRRSCPVAHPF-LMSGPIPDPVGRLEHLP 168

Query: 172 --LNYEPVGGDIYSEESV------TGHHLKFTARDEPMITLP-------RQFASREWYVI 216
                 P   +    + V       G   + T  D PM  +P       R++ +R+ YV 
Sbjct: 169 LNRRRPPGDEETVRVDFVTGAPHGDGSISRMTLNDVPMEPVPGSPDPRRRRYLTRQVYVT 228


>UniRef50_D1Y486 Crispr-associated protein Cas5 n=1 Tax=Pyramidobacter piscolens
           W5455 RepID=D1Y486_9BACT
          Length = 269

 Score =  181 bits (459), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 64/229 (27%), Positives = 93/229 (40%), Gaps = 36/229 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              LILRL GP+ A+G    +  RPT   P  S + GL+   LG    D   LQ L E +
Sbjct: 1   MDALILRLRGPLMAFGDVAVDEIRPTDLLPGLSEMTGLIANALGWTFQDVEKLQRLQERL 60

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYR------------GLKSHETIQTWRE 109
           + A R D         +   LRDY T   + ED              G K   T+Q +R 
Sbjct: 61  RLASREDR--------TGVPLRDYQTARLSSEDSLWRTDGIVAERGGGSKGEFTVQRYRH 112

Query: 110 YLCDASFTVALWLTP-HATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQ 168
           Y  DA+ TV + L P      + E+  A+  P    ++GR  CP + P+           
Sbjct: 113 YRADAAVTVLIALDPADEAPALEEIRDALRHPARPLFIGRIGCPPSQPIC---------- 162

Query: 169 KALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIK 217
                +EP G +I   +S+    +  T R        R+ ASR   +++
Sbjct: 163 -----FEPEGREIIHTDSLKDAIMHITPRAPLGAQTKREPASRNKVLVE 206


>UniRef50_D0WFC8 CRISPR-associated protein Cas5 n=1 Tax=Slackia exigua ATCC 700122
           RepID=D0WFC8_9ACTN
          Length = 267

 Score =  180 bits (458), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 57/201 (28%), Positives = 96/201 (47%), Gaps = 20/201 (9%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+L+LA P+Q+WG  +    R T   P++SG++GLL A LG +R+D  S+  L+ ++
Sbjct: 4   MTVLLLKLAAPLQSWGASSRFTERTTRHEPSKSGVIGLLAAALGRRRED--SVDDLA-AL 60

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLK---SHETIQTWREYLCDASFTV 118
           +FAVR D+          + +RD+ T    + D    +   +     + R+YL DA F  
Sbjct: 61  RFAVRIDQ--------PGSFMRDFQTEHTRKWDSDTRRFVFNESLSLSKRDYLSDAVFVA 112

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVG 178
           AL        +++E  +A+  P +  +LGRRSCP +  ++LG        +AL +     
Sbjct: 113 ALE---GDEDLLAECAEALHHPAFPLFLGRRSCPPSTQVYLGLVDGP-MMEALADIPWQA 168

Query: 179 GD--IYSEESVTGHHLKFTAR 197
            +          G   K T  
Sbjct: 169 TERHWNYAYRFRGDKPKETVE 189


>UniRef50_B4S8P8 CRISPR-associated protein Cas5 family n=8 Tax=Bacteria
           RepID=B4S8P8_PROA2
          Length = 243

 Score =  180 bits (457), Expect = 3e-44,   Method: Composition-based stats.
 Identities = 59/244 (24%), Positives = 93/244 (38%), Gaps = 32/244 (13%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
           YL+L L  P+Q+WG  +  G R T  FPT+SG+LG+L   LG   +    L+ ++   Q 
Sbjct: 5   YLLLWLEAPLQSWGADSRFGRRGTLEFPTKSGVLGMLCCSLGAGGEQKELLEKMAPLKQS 64

Query: 64  AV--------RCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKS--------------H 101
           A+        R +E+   DR      LRD+H V    +D    ++               
Sbjct: 65  AISFCRTSKFRQEEIKKLDRE---PLLRDFHMVGSGYDDKNPWETLLIPKKSDGTTAVNG 121

Query: 102 ETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGT 161
            +  T+R YL DA F V + +      +      A+  P +  Y GR+ C  T  ++ G 
Sbjct: 122 GSKITYRYYLQDAVFAVIMEVPSEKLTLF---ADALENPCWDIYFGRKCCAPTDFIYRGC 178

Query: 162 CQASDP-QKALLNYEPVGGDIYSEESVTGHHLK--FTARDEPMITLPRQ-FASREWYVIK 217
                      L        +     V G H        D P+    ++ +  R   VI 
Sbjct: 179 FNTESLAIGKALEIAQEKRLMEDFRVVDGEHEGEAIVLNDVPIQFGEQKLYRERRVTVIS 238

Query: 218 GGMD 221
              +
Sbjct: 239 CANE 242


>UniRef50_Q1EQS9 CRISPR-associated protein n=3 Tax=Streptomyces RepID=Q1EQS9_STRKN
          Length = 280

 Score =  180 bits (456), Expect = 4e-44,   Method: Composition-based stats.
 Identities = 71/235 (30%), Positives = 107/235 (45%), Gaps = 39/235 (16%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           L+LRL+GP+Q+WG+ +    R T RFPTRSG++G+L A LG +R +   +  L+  +   
Sbjct: 14  LLLRLSGPLQSWGERSHFNERDTARFPTRSGIIGMLAAALGRRRGE--PVDDLAR-LSLT 70

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHE---------TIQTWREYLCDAS 115
           VR D             LRD HTV G       + + E         T+ T R YL DA+
Sbjct: 71  VRTDR--------PGILLRDLHTVGGGLPAKATVTTAEGKKRPGTTGTLLTHRTYLADAA 122

Query: 116 FTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQAS------DPQK 169
           FT+AL  TP    ++ +  +A+  P +  +LGRRSCP   PL LG  + +       P  
Sbjct: 123 FTIALTSTPDDRPLLDQAAQALNTPCWPLFLGRRSCPPEGPLLLGASEDALHHLVHLPLA 182

Query: 170 ALLNYEPVGGDIYSEESV-------------TGHHLKFTARDEPMITLPRQFASR 211
           A         +  ++  +              G H      D+P+   PR+ + R
Sbjct: 183 AHPGRGQQDTEFLADRPLNRLPYGTATPVGADGTHPSGEVNDQPLSFDPRRRSYR 237


>UniRef50_A5UR14 CRISPR-associated protein, Cas5e family n=1 Tax=Roseiflexus sp.
           RS-1 RepID=A5UR14_ROSS1
          Length = 262

 Score =  179 bits (455), Expect = 6e-44,   Method: Composition-based stats.
 Identities = 68/205 (33%), Positives = 94/205 (45%), Gaps = 45/205 (21%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L LRL GP+Q+WG     G R T   PT+SG++GLLG  LG++RDD + L+ LS+++
Sbjct: 1   MNTLFLRLEGPLQSWGLRARWGERDTTDAPTKSGVIGLLGCALGLRRDD-ARLRDLSDNL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKS--------------------- 100
           +  VR D        +    +RDYHT  G R                             
Sbjct: 60  RMGVRVD--------LPGILMRDYHTTGGGRYSTIASTGGPRYHDEPYIGGVLSAEVTKG 111

Query: 101 ------------HETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGR 148
                        ET  + R YL DASF VAL  +P     I EL  A+  P +  +LGR
Sbjct: 112 RIKVKINQKTGEPETDVSERYYLADASFLVALQGSPD---YIGELATAIQSPVWPLFLGR 168

Query: 149 RSCPLTHPLFLGTCQASDPQKALLN 173
           ++C  + P+F GT Q    + AL N
Sbjct: 169 KACVPSTPIFAGTGQFDILEDALKN 193


>UniRef50_C9M2Y8 CRISPR-associated protein n=1 Tax=Lactobacillus helveticus DSM
           20075 RepID=C9M2Y8_LACHE
          Length = 241

 Score =  179 bits (454), Expect = 7e-44,   Method: Composition-based stats.
 Identities = 51/201 (25%), Positives = 90/201 (44%), Gaps = 17/201 (8%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M++   +RL  P+Q++G       R +  +P++S ++G++ A LG +RDD   LQ    +
Sbjct: 1   MKTA-TIRLTAPLQSYGNQASFNQRTSDNYPSKSAVIGIIAAALGYRRDDARILQ--LNN 57

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           + FAVR ++        S   + ++ TV   +   +  +      T+RE++ DA F VA+
Sbjct: 58  LLFAVRIEQ--------SGNMMTEFQTVEYQKSSTKTARK----LTYREFIQDAVFMVAI 105

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180
                    I ++  A+  P++  YLGRRS P   PL + T    +P + L         
Sbjct: 106 --GSDNDHEIEKIVSALKHPKFQLYLGRRSNPPAGPLMIETYDEENPLQVLEKLSWQAEP 163

Query: 181 IYSEESVTGHHLKFTARDEPM 201
            Y +       L     D  +
Sbjct: 164 WYQKRLRAPKFLTRIIADAEL 184


>UniRef50_D0Y918 CRISPR-associated protein Cas5 family n=2 Tax=Dehalococcoides
           RepID=D0Y918_9CHLR
          Length = 205

 Score =  179 bits (454), Expect = 7e-44,   Method: Composition-based stats.
 Identities = 64/213 (30%), Positives = 106/213 (49%), Gaps = 19/213 (8%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
            L++RL GPMQ+WG  +    R T   PTRSG++GL+ A +GI RD+     A  + ++ 
Sbjct: 6   TLLMRLEGPMQSWGYRSRFDCRDTALEPTRSGVIGLICAAMGIARDEDI---ARFDGIRM 62

Query: 64  AVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLT 123
            VR D     ++        DYHT L   +        +T+ ++R+YL DASFTV L  +
Sbjct: 63  GVRVDRDGKVEQ--------DYHTALDVIK--ADGSGKDTVVSYRDYLTDASFTVGLESS 112

Query: 124 PHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDIYS 183
                ++ ++ KA++ P++  +LGR++ PLT P      + S+P K     E +     +
Sbjct: 113 --DRNLLEKIAKALVSPQWVLFLGRKAFPLTKPP---IFEFSNPVKPGSLEEHLLCGASA 167

Query: 184 EES-VTGHHLKFTARDEPMITLPRQFASREWYV 215
           +   +     + T  D P+    R+F  R + V
Sbjct: 168 KRVLLESPDGERTQYDWPLCFGERRFKPRRFTV 200


>UniRef50_A5GBK2 CRISPR-associated protein Cas5 family n=2 Tax=Deltaproteobacteria
           RepID=A5GBK2_GEOUR
          Length = 231

 Score =  178 bits (451), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 61/225 (27%), Positives = 98/225 (43%), Gaps = 10/225 (4%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE-- 59
           +S+L LRL GP+Q+WG  +    R TG  PT+S + G+  A LG  R      + L    
Sbjct: 10  KSFLALRLEGPLQSWGFDSQYNRRNTGLMPTKSAIAGMCCAALGFLRGCDKEQEFLVAFG 69

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
           +V+            + + V  L+DYHTV   R    G  +++ + T R+YL DA+F V 
Sbjct: 70  AVRMTAIAIPRNGAKKELPVRRLQDYHTVQNTRR-ASGAINNDCVLTHRQYLTDAAFGVL 128

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGG 179
           L      + ++ ++  A+  P +  +LGR++C  T P+  G  +  D    LL  +    
Sbjct: 129 LE---GDSTLLKQIAAALENPVWGVWLGRKTCIPTAPVLAGLRENRDEALKLLLKDKPLE 185

Query: 180 DIYSEESVT---GHHLKFTARDEPMITLPRQFASREWYVIKGGMD 221
               +E V                  T  R F+ R    ++ G D
Sbjct: 186 SFARQEDVESFADGRDSLPDMPVSFATERRIFSPRRVRTLQ-GTD 229


>UniRef50_C7MTB0 CRISPR-associated protein Cas5 n=1 Tax=Saccharomonospora viridis
           DSM 43017 RepID=C7MTB0_SACVD
          Length = 255

 Score =  178 bits (451), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 75/234 (32%), Positives = 107/234 (45%), Gaps = 36/234 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            S L+LRLAGP+Q+WG+ +    R T  FPT SGLLGLL   +G +R +  SL+ L+ ++
Sbjct: 1   MSGLLLRLAGPLQSWGERSTFDVRDTAGFPTHSGLLGLLACVMGRRRGE--SLEDLA-AL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGARE--------DYRGLK-SHETIQTWREYLC 112
            F +R D           T + DY T  GA          D +G      T+QTWREYL 
Sbjct: 58  TFTIRVDR--------PGTRIIDYQTAGGALPPSMKVPTADGKGRPAGKGTVQTWREYLA 109

Query: 113 DASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALL 172
           DA F VA+      + V+ ++  A+  P + PYLGRRSCP   PL L      DP   L 
Sbjct: 110 DAVFVVAV---QGPSEVLDQVRHALRYPHWQPYLGRRSCPPDQPLLLDV-PVEDPVAELC 165

Query: 173 NYEPVGGDIYSEESV------------TGHHLKFTARDEPMITLPRQFASREWY 214
              P+   +  +E               G   +         ++ R ++ R  +
Sbjct: 166 TRVPLARRVGKDEETVPVDFIFPVERRDGVRSEIHDVPVAFTSVDRAYSPRPVW 219


>UniRef50_D1A6Q5 CRISPR-associated protein Cas5 family n=2 Tax=Actinomycetales
           RepID=D1A6Q5_THECD
          Length = 273

 Score =  178 bits (451), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 70/243 (28%), Positives = 102/243 (41%), Gaps = 44/243 (18%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+L L+GP+Q+WG+ +    R T   PTRSGL+G++ A  G +R  T  +  L  ++
Sbjct: 6   TTGLLLHLSGPLQSWGERSRFNQRDTATAPTRSGLIGMIAAAFGRRR--TEPVTDL-RAL 62

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLG---------AREDYRGLKSHETIQTWREYLC 112
           +F VR D           T LRD+HTV G           E  R      T+ + R YL 
Sbjct: 63  RFTVRIDR--------PGTLLRDFHTVGGGMPRDLTVITAEGKRRAADTATVTSDRYYLQ 114

Query: 113 DASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALL 172
           DA+FTVA+        ++    +A+  PR+  YLGRRSCP   PL L T   +DP  AL+
Sbjct: 115 DAAFTVAVTA--DDPALLDRCAQALRAPRWPLYLGRRSCPPNAPLLL-TVLRTDPVTALI 171

Query: 173 NYEP---------------------VGGDIYSEESVTGHHLKFTARDEPMITLPRQFASR 211
           +                              S       + +            R+F +R
Sbjct: 172 DLPLARTAPRDRGDVLVEFRSDTPFESRAWPSAPEDEQVYTEAQDEPVSFQPHHRRFQTR 231

Query: 212 EWY 214
             Y
Sbjct: 232 PIY 234


>UniRef50_A8ZZ17 CRISPR-associated protein Cas5 family n=1 Tax=Desulfococcus
           oleovorans Hxd3 RepID=A8ZZ17_DESOH
          Length = 259

 Score =  177 bits (449), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 60/170 (35%), Positives = 84/170 (49%), Gaps = 20/170 (11%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
           YL+ RL GPM +WG+     TR T  +P RS ++GL+ A LGI+R +T + QAL +    
Sbjct: 3   YLLFRLYGPMASWGEIAVGETRHTANYPGRSAIIGLMAAALGIKRSETENQQALDQGCLI 62

Query: 64  AVRCDELILDDRRVSVTGLRDYHT----------VLGAREDYR--GLKSHETIQTWREYL 111
           AV        + R   + LRDYHT          V   R D    G     TI + REY 
Sbjct: 63  AV--------EARSHGSLLRDYHTTQVPDSVGGFVYRTRRDELIIGKPRLGTILSSREYR 114

Query: 112 CDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGT 161
            DA    A+ + P A   +  ++  + +PR   YLGR+SCPL+ P+    
Sbjct: 115 QDALAVSAVRVLPGARYELQTIKTHLEQPRLHVYLGRKSCPLSAPMNPQI 164


>UniRef50_A8SDR7 Putative uncharacterized protein n=1 Tax=Faecalibacterium
           prausnitzii M21/2 RepID=A8SDR7_9FIRM
          Length = 220

 Score =  177 bits (449), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 75/217 (34%), Positives = 102/217 (47%), Gaps = 24/217 (11%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+LRLA P+QAWG  +   TR TGR PT+SG++GLL A LG++RD++ +L  L+  +
Sbjct: 1   MATLLLRLAAPLQAWGADSKFETRKTGREPTKSGVIGLLAAALGLRRDESEALTRLT-GL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +F VR +             L DYHT        +      +  T+R YL DA F   + 
Sbjct: 60  RFGVRVER--------EGQLLVDYHTA-------KTQDEKTSYVTYRHYLQDAVFLAGIE 104

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPV-GGD 180
            T  A +   +     L P +  YLGRR CP T PL LG C  S  Q+ L    P+  G 
Sbjct: 105 STDTALLQQLQQAL--LHPAFPLYLGRRCCPPTLPLCLGVCPGS-LQEVLQAEPPLCPGR 161

Query: 181 IYSEESVTGHHLKFTA--RDEPMITLP--RQFASREW 213
                         TA  RD P+   P  RQ+  R  
Sbjct: 162 QSRILLDADPLEPGTAPQRDVPVSFDPHHRQYGYRSV 198


>UniRef50_A7BA63 Putative uncharacterized protein n=1 Tax=Actinomyces odontolyticus
           ATCC 17982 RepID=A7BA63_9ACTO
          Length = 242

 Score =  177 bits (448), Expect = 3e-43,   Method: Composition-based stats.
 Identities = 64/205 (31%), Positives = 94/205 (45%), Gaps = 23/205 (11%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M + L+LRLAGPMQ+WG  +    R T  FPT+S L+GLLGA  G +R D   ++ L+E 
Sbjct: 1   MSAVLVLRLAGPMQSWGADSRFTRRSTEAFPTKSALVGLLGAAQGRRRSD--PIEDLAE- 57

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           +  AVR D+            L D+HT                  + R Y  DA+F   +
Sbjct: 58  LSVAVRVDQ--------PGQLLHDFHTAHRG--------DTSMPLSHRFYRADAAFGAFI 101

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180
                   +I  L +A+++P +  YLGRRSCP T PL L   + S    A+     +   
Sbjct: 102 EGPDD---MIDALAQAIVRPVFPLYLGRRSCPPTLPLRLAVREGSAW-DAVRETPWMAST 157

Query: 181 IYSEESVTGHHLKFTARDEPMITLP 205
            Y ++    H ++     +  I  P
Sbjct: 158 YYQKKQRHDHFVRMRVVADLGIIPP 182


>UniRef50_A6W168 CRISPR-associated protein Cas5 family n=6 Tax=Gammaproteobacteria
           RepID=A6W168_MARMS
          Length = 258

 Score =  176 bits (446), Expect = 5e-43,   Method: Composition-based stats.
 Identities = 71/189 (37%), Positives = 97/189 (51%), Gaps = 21/189 (11%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M+ YL+ RL GPM +WGQP   G R T   PTRS +LGLLGA LGI+RDD   L AL  S
Sbjct: 1   MKDYLVFRLYGPMASWGQPAVGGDRATAIAPTRSAILGLLGAALGIKRDDAQQLDALHSS 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL-------------KSHETIQTW 107
           VQ A +        +    + LRDYHT      + + +             +   TI + 
Sbjct: 61  VQMATK--------QVTPTSLLRDYHTSQVPSRNNKYVYRTRKNELLDEHKEKLNTILST 112

Query: 108 REYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDP 167
           R+Y CD  + VA+ LT  +   +  L++A++KP Y   LGR+SCPL  PL      +   
Sbjct: 113 RDYRCDGIWIVAVSLTQESLFSLERLKQALIKPVYVLSLGRKSCPLAAPLLPVLLTSVSL 172

Query: 168 QKALLNYEP 176
           ++AL    P
Sbjct: 173 REALDYPFP 181


>UniRef50_B8HWH8 CRISPR-associated protein Cas5 family n=1 Tax=Cyanothece sp. PCC
           7425 RepID=B8HWH8_CYAP4
          Length = 216

 Score =  176 bits (446), Expect = 6e-43,   Method: Composition-based stats.
 Identities = 53/217 (24%), Positives = 92/217 (42%), Gaps = 23/217 (10%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M + L+LR+  PM +WG  +    R + R PT+S ++GLL A LG  R    ++  L+ +
Sbjct: 1   MPT-LLLRMRAPMMSWGDHSRFTIRDSRREPTKSAVIGLLCAALGRPR--WEAVADLT-A 56

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           ++  VR ++  L           DYHTV  + +         T+ + R Y+ DA + V L
Sbjct: 57  LKMGVRINQEGLVQC--------DYHTVQDSIK--SSGSKGNTVISHRYYIADADYLVGL 106

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180
             +      +  L+ A+  P +  Y GR+S   + P+ L         +AL +   +   
Sbjct: 107 EGS--DRHFLESLDSALQSPIWQVYFGRKSFVPSCPVALHVSDQP-LAEALKHRITLSKT 163

Query: 181 IYSEE------SVTGHHLKFTARDEPMITLPRQFASR 211
           +  +        +         +D P+    R F SR
Sbjct: 164 MAHKLPNRLRCVLEVPDSLDVRQDVPLDWQKRHFGSR 200


>UniRef50_B1VIY0 CRISPR-associated protein n=9 Tax=Actinomycetales
           RepID=B1VIY0_CORU7
          Length = 240

 Score =  175 bits (445), Expect = 7e-43,   Method: Composition-based stats.
 Identities = 59/218 (27%), Positives = 95/218 (43%), Gaps = 26/218 (11%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M   L+L L GPMQ+WG  +    R T   PT+SG++GL+ A  G +R D   ++ L++ 
Sbjct: 1   MAHSLLLLLKGPMQSWGDESRFSVRATATTPTKSGIVGLIAAAQGRRRTD--GVEDLAK- 57

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           ++ AVR D+        S + LRDY T       +            R +L DA+F  A+
Sbjct: 58  LRMAVRVDQ--------SGSLLRDYQTAQ----PWLKNPGANASLVTRYFLSDAAFVAAV 105

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180
                   ++ ++ +A+ +P Y  Y+GRRSCP+   L +G     D + AL  ++     
Sbjct: 106 E--SEDRELLDQMAEALRRPAYPLYMGRRSCPVHPGLVIGVVDG-DAESALRAHDTWHAT 162

Query: 181 IYSEESVTGHHLKFTARD--------EPMITLPRQFAS 210
               +           RD         P   +P  F+ 
Sbjct: 163 AVHRKESPKKVSLAIYRDANPGEGGSVPRQDVPVSFSP 200


>UniRef50_B3E5U9 CRISPR-associated protein Cas5 family n=2 Tax=Desulfuromonadales
           RepID=B3E5U9_GEOLS
          Length = 271

 Score =  175 bits (443), Expect = 1e-42,   Method: Composition-based stats.
 Identities = 81/250 (32%), Positives = 114/250 (45%), Gaps = 37/250 (14%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             YL+ RL GP+ +WG+     +R +  +P +S LLGL+ A LGI+RD+     AL+   
Sbjct: 1   MKYLLFRLYGPLASWGEIAVGESRHSAVYPGKSALLGLIAAALGIRRDEEQRQAALASGY 60

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLG----------AREDY--RGLKSHETIQTWRE 109
           +FAV+           +   LRDYHT              R D    G +   TI + RE
Sbjct: 61  RFAVKV--------ISTGHPLRDYHTAQAPDSVGKFVYRTRRDELVLGKERLGTILSSRE 112

Query: 110 YLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQK 169
           Y CDA   VA+     A   + E+ +A++KPR+  YLGR+SCP+  PL      A     
Sbjct: 113 YRCDAFSLVAVVAEDDAPYSLDEIREALMKPRFHLYLGRKSCPVAAPLNPLVRDAVGFGD 172

Query: 170 ALLNYEPVGGDIYS--------EESVTGHHL-------KFTARDEPMITLPRQFASREWY 214
           AL +Y P G    S        +E V G  L       KF+  DE +    +Q   R ++
Sbjct: 173 ALDSY-PYGALFVSSWLMKTAQKEIVEGGKLAEVPSLAKFSREDETVFAYNKQPV-RYYW 230

Query: 215 VIKGGMDVSQ 224
               G  VSQ
Sbjct: 231 EGDAGDLVSQ 240


>UniRef50_A1ARH6 CRISPR-associated protein, Cas5e family n=2 Tax=Bacteria
           RepID=A1ARH6_PELPD
          Length = 232

 Score =  175 bits (443), Expect = 1e-42,   Method: Composition-based stats.
 Identities = 58/204 (28%), Positives = 86/204 (42%), Gaps = 17/204 (8%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M + L+LRL GPMQ+WG  +    R TG+ P++SG++GLL A LGI R++   L+ L+  
Sbjct: 1   MPT-LLLRLVGPMQSWGTTSRFDQRDTGKEPSKSGVVGLLAAALGIDRENWVDLEPLT-C 58

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDY-----RGLKSHETIQTWREYLCDAS 115
           +   VR D              RDY T   A  D              + + R YL DA+
Sbjct: 59  LAMGVRHDR--------PGVPKRDYQTAGCASTDTIIKADGTQAKGGGVVSQRFYLADAA 110

Query: 116 FTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYE 175
           F V L        ++  +  A+  P +T  LGR+S   +  +++       P    L   
Sbjct: 111 FLVGLEC--DDNCLLERIHVALHNPFWTLALGRKSYVPSESIWIVDGVRDAPLLETLKRY 168

Query: 176 PVGGDIYSEESVTGHHLKFTARDE 199
           P      S E      L     D+
Sbjct: 169 PWIASSRSREEPPERLLVSIESDD 192


>UniRef50_UPI0001AF1D4C CRISPR-associated protein, CT1976 n=1 Tax=Streptomyces ghanaensis
           ATCC 14672 RepID=UPI0001AF1D4C
          Length = 244

 Score =  174 bits (442), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 54/188 (28%), Positives = 83/188 (44%), Gaps = 20/188 (10%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L++    PMQ+WG  +   +R T   PT+SG++GLL A LGI RD    +Q L+E +
Sbjct: 1   MATLLMCFDAPMQSWGTRSQFASRDTATEPTKSGVVGLLAAALGIPRDADEEIQNLAE-L 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +  VR D   + +         D+HTV          K+H T  T R YL DA F V + 
Sbjct: 60  RMGVRVDREGVVEA--------DFHTVQNVPNTE--GKNHRTAVTKRFYLADALFLVGVE 109

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPL-FLGT------CQASDPQKALLNY 174
                T ++ +L  A+  PR+  Y GR++     P+   G               AL  +
Sbjct: 110 --SDDTQLLHQLHTALTAPRWPLYFGRKAFVPARPIPSPGLAGEHHPVTGQSLDDALRTH 167

Query: 175 EPVGGDIY 182
             +   + 
Sbjct: 168 PWLENQLR 175


>UniRef50_D2L2X8 CRISPR-associated protein Cas5 family n=1 Tax=Desulfovibrio sp.
           FW1012B RepID=D2L2X8_9DELT
          Length = 266

 Score =  174 bits (442), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 70/249 (28%), Positives = 98/249 (39%), Gaps = 45/249 (18%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M  YLI +L G + A+G       R +   PTRS + GLL ACLGI+R + + L ALS  
Sbjct: 1   MARYLIFQLYGMLAAYGLVAVGEVRLSAGHPTRSAVFGLLAACLGIRRHEEARLAALSGG 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL---------------KSHETIQ 105
              AVR D           T L DYHT+    E  + +               +   T+ 
Sbjct: 61  YALAVRVD--------APGTSLLDYHTIQTPPEKSKRIYRTRADELGGLLGIDEPPYTVL 112

Query: 106 TWREYLCDASFTVALW------LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFL 159
           + R YLCDA FT  L               +  L +A+ +P  TPYLGR+SCP + P   
Sbjct: 113 SRRGYLCDAHFTACLTPAAAPPTDATPPHTLEALAEALRRPVLTPYLGRKSCPPSLPFHP 172

Query: 160 GTCQASDPQKALLNY------------EPVGGDIYSEESVTGHHLKFT----ARDEPMIT 203
              +    + AL +Y                  ++++E         T     RD  +  
Sbjct: 173 RLGEYDSLEAALADYPLEKLAFPAGLKPHDPAVVFADEDEAITPATVTSRPLVRDRTVQH 232

Query: 204 LPRQFASRE 212
             R F  R 
Sbjct: 233 GRRLFEERR 241


>UniRef50_C9M9R7 CRISPR-associated protein Cas5, Ecoli subtype n=1 Tax=Jonquetella
           anthropi E3_33 E1 RepID=C9M9R7_9BACT
          Length = 243

 Score =  174 bits (440), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 56/183 (30%), Positives = 84/183 (45%), Gaps = 19/183 (10%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             +L+LR  GPM ++G    +  RP  RFP  S + GL+   LG    +T  LQAL + +
Sbjct: 1   MDFLVLRFRGPMMSFGDVAVDEQRPIDRFPGVSMVTGLVANALGWDWSETEKLQALQDRL 60

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHT----------VLGAREDYRGLKSHETIQTWREYL 111
             AVR D         +   LR+Y T          V  +    R L    T+Q +  Y 
Sbjct: 61  VLAVREDR--------AGERLREYQTVALPGKSGLFVTHSIPCSRNLDKPMTVQKYLSYW 112

Query: 112 CDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLG-TCQASDPQKA 170
            ++  T  + LT   T  + E+  A+ KP    +LGR++C  T P+F G    A  P++A
Sbjct: 113 ANSLITCFIALTGLGTPTLDEIACALKKPARPLFLGRKTCLPTEPVFRGEIFGAESPEEA 172

Query: 171 LLN 173
           +L 
Sbjct: 173 VLR 175


>UniRef50_Q5YRB6 Putative uncharacterized protein n=1 Tax=Nocardia farcinica
           RepID=Q5YRB6_NOCFA
          Length = 235

 Score =  172 bits (435), Expect = 9e-42,   Method: Composition-based stats.
 Identities = 63/231 (27%), Positives = 99/231 (42%), Gaps = 36/231 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+LRLA P+Q+WG  +    R T ++P++SG+LGL+ A  G +R D   ++   +++
Sbjct: 1   MTVLLLRLAAPLQSWGVASRFARRETQQYPSKSGILGLIAAARGHRRTD--PIEEALQNL 58

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
            F VR D+            +RD+   L         K+ +   + R YL DA F  A+ 
Sbjct: 59  AFGVRVDQ--------PGRLIRDFQVALNID------KTKQFPLSQRYYLADAVFLAAI- 103

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                  +I  +  A+ +P +  YLGRRSCP+T PL LG  +    + AL   E      
Sbjct: 104 --QGERGLIEGIGNALRRPEFPLYLGRRSCPVTGPLVLGEPRDVTLEHALHETEWQAATW 161

Query: 182 YSEES---------------VTGHHLKFTARDEPMITLP--RQFASREWYV 215
           Y                        L+   RD P+   P  R++  R    
Sbjct: 162 YRRSQHRRVRLPIYRDLLPGDPVELLREQVRDMPLSFDPVRREYGWRTVVE 212


>UniRef50_B2GBJ9 Putative uncharacterized protein n=1 Tax=Lactobacillus fermentum
           IFO 3956 RepID=B2GBJ9_LACF3
          Length = 235

 Score =  172 bits (435), Expect = 1e-41,   Method: Composition-based stats.
 Identities = 54/206 (26%), Positives = 83/206 (40%), Gaps = 23/206 (11%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQR--DDTSSLQALSE 59
              L++R+A P+Q++G P     R T R P++S ++G++GA LG +R  DD  SL  L  
Sbjct: 1   MKTLVIRIAAPLQSYGDPASFEKRTTFRAPSKSAVIGMIGAALGFRRESDDYKSLNDLD- 59

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
              FAVR D+            L D+     + +            + R YL DA F VA
Sbjct: 60  ---FAVRVDQ--------PGEVLSDFQITHYSLK-------KPGKLSHRIYLQDAVFMVA 101

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGG 179
           L     A  ++ E+E A+  P++  Y GRRS P    L +  C        L        
Sbjct: 102 LSSKQDA--LMEEIEYALRHPKFQLYFGRRSNPPAGILKMKMCPDKTAINVLKELPWQAS 159

Query: 180 DIYSEESVTGHHLKFTARDEPMITLP 205
             +  +            D  ++   
Sbjct: 160 VWFQRKYKKDVFNARIYADAKLVPDR 185


>UniRef50_Q2JWC5 CRISPR-associated protein Cas5, Ecoli subtype n=1 Tax=Synechococcus
           sp. JA-3-3Ab RepID=Q2JWC5_SYNJA
          Length = 207

 Score =  170 bits (430), Expect = 4e-41,   Method: Composition-based stats.
 Identities = 53/217 (24%), Positives = 92/217 (42%), Gaps = 31/217 (14%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L++RL  PM +WG  +    R + R PT+S ++G+L A LG  R     +  L+ ++
Sbjct: 1   MTTLLMRLRAPMMSWGDHSQFDYRDSRREPTKSAVIGILCAALGRPR--WEPVDDLA-AL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +  VR ++             +D+HTV             ETI + R Y+ D  + V L 
Sbjct: 58  KMGVRVNK--------EGILCKDFHTVQ----------IKETI-SNRYYVADGDYLVGLE 98

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                  ++  L++A+ KP +  +LGR+S   + PL +G  +     +AL  +       
Sbjct: 99  ---GDPNLLRTLDQALQKPYWQVFLGRKSFIPSRPLRVGLVEQP-LLEALRQHPYECSRR 154

Query: 182 YSEES-----VTGHHLKFTARDEPMITLPRQFASREW 213
               S     +         +D P+   PR+F  R  
Sbjct: 155 GKRPSQLRFVLEVSESLDVRQDVPLSWQPRRFGCRAV 191


>UniRef50_Q47PI7 CRISPR-associated protein, Cas5e family n=12 Tax=Actinomycetales
           RepID=Q47PI7_THEFY
          Length = 245

 Score =  169 bits (428), Expect = 6e-41,   Method: Composition-based stats.
 Identities = 68/228 (29%), Positives = 97/228 (42%), Gaps = 36/228 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L L LAGP+QAWG  +    R T   PT+SG+LGLL A  G +R D   L  L+ ++
Sbjct: 1   MKVLTLLLAGPLQAWGAASRFTRRTTEHAPTKSGVLGLLAAAQGRERTD--DLSDLA-AL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +F VR D+          T +RD+ T +                + R YL DA F  A+ 
Sbjct: 58  RFGVRVDQR--------GTRIRDFQTAIHLD------TGKSMPVSERFYLADAVFVAAVE 103

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                  +I  L +AV  P Y PYLGRRSCP + P+ LG       ++ L   +    + 
Sbjct: 104 ---GEDTLIDTLHQAVQHPVYLPYLGRRSCPPSRPINLGVHSGKPLEQVLAEEKWHAANW 160

Query: 182 YSEESVTGHHLKF--------------TARDEPMITLP--RQFASREW 213
           Y  +      +                + RD P+   P  R++A R  
Sbjct: 161 YQRQLRDLPEVPLDLLVDAPPGDPGADSLRDLPISFDPVHRRYALRGV 208


>UniRef50_Q2JH27 CRISPR-associated protein, CT1976 n=6 Tax=Actinomycetales
           RepID=Q2JH27_FRASC
          Length = 276

 Score =  167 bits (424), Expect = 2e-40,   Method: Composition-based stats.
 Identities = 76/253 (30%), Positives = 99/253 (39%), Gaps = 56/253 (22%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
           R  L+LRLAGP+Q+WG  +    R T   PT+SG++GLL A  G +R D   ++ L  S+
Sbjct: 7   RHCLVLRLAGPLQSWGSRSMFNRRDTLTEPTKSGIIGLLAAAQGRRRTD--PIEDLL-SL 63

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGARE-------------DYRGLKSHETIQTWR 108
              +R D+          T LRDYHTV   R                    +  T  T R
Sbjct: 64  TLGIRTDQ--------PGTLLRDYHTVSDYRGRPLPSAAVSAKGLQKPTSPAKHTHVTER 115

Query: 109 EYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQ 168
            YL DA F  AL        V++ L  A+  P +   LGRR+CP THPL L     S+P 
Sbjct: 116 FYLQDAVFVAALAAPE---PVLTTLADALRTPAFPLALGRRACPPTHPLLL--VPDSEPD 170

Query: 169 KAL--------LNYEPVGGDIYSEE-----------------SVTGHHLKFTARDEPMIT 203
            AL        L   P        +                 +V          D P   
Sbjct: 171 AALWSGSALEVLRQVPWQARPDHRDALARRRPPRLRRIDLPVTVDDPDGDDVRIDLPTTF 230

Query: 204 LPRQ--FASREWY 214
            P Q  F SR  +
Sbjct: 231 DPHQRGFTSRRVH 243


>UniRef50_B4UE71 CRISPR-associated protein Cas5 family n=2 Tax=Anaeromyxobacter
           RepID=B4UE71_ANASK
          Length = 246

 Score =  167 bits (424), Expect = 2e-40,   Method: Composition-based stats.
 Identities = 58/188 (30%), Positives = 89/188 (47%), Gaps = 6/188 (3%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M   LILR   P+ A+G    +     G FP  S + GL+   LG    D   L+AL   
Sbjct: 1   MLDALILRFDAPLLAFGGVAVDNHGEVGDFPGLSMVAGLIANALGYDHRDCDRLEALQRR 60

Query: 61  VQFAVRCD---ELILDDRRVSV--TGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDAS 115
           ++ AVR D   + ++D + V++    L    T  GA E   G  S  T   +R Y  DA 
Sbjct: 61  LRIAVRRDRSGQRLVDFQTVALGQPFLERGWTTRGAVEGRDGAFSDGTHIRYRAYWADAV 120

Query: 116 FTVALWLTPHAT-MVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNY 174
           +T+A+ L P A    +  +E+A+ +P    +LGR++C  + P+  G  Q      AL ++
Sbjct: 121 YTLAVTLDPPAESPGLDAVERALREPERPLFLGRKACLPSVPILAGRLQIPSLLAALASF 180

Query: 175 EPVGGDIY 182
           E V  D +
Sbjct: 181 ERVSKDRW 188


>UniRef50_B8IZA7 CRISPR-associated protein Cas5 family n=1 Tax=Desulfovibrio
           desulfuricans subsp. desulfuricans str. ATCC 27774
           RepID=B8IZA7_DESDA
          Length = 249

 Score =  166 bits (421), Expect = 4e-40,   Method: Composition-based stats.
 Identities = 58/225 (25%), Positives = 95/225 (42%), Gaps = 42/225 (18%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE----- 59
           L LRL  PM ++G  +    R T   P++S + G+L A  G+ R        L +     
Sbjct: 8   LALRLQAPMLSFGNESRFNRRCTASLPSKSVVAGMLCAAKGLHRGSVEEQAFLQQVAAIP 67

Query: 60  SVQFAV-RCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV 118
            +  A+ RC      D  ++     D+HTV G R+   G+K  +   T R YL D+SF V
Sbjct: 68  MLSVAIPRCLSANGKDWLLAAGRTVDFHTVQGTRKAAGGIK--DCHITTRHYLHDSSFAV 125

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVG 178
            L        V+ +  +A+  P +  ++GR+ C  + P+F                    
Sbjct: 126 FL---NGPYRVLEDAARALQNPVWGLWIGRKCCIPSAPVF-------------------- 162

Query: 179 GDIYSEESVTGHHLKFTARDEPMITLPRQFAS--REWYVIKGGMD 221
           G ++S E+V  +H         M+  P +F +  RE +  + G D
Sbjct: 163 GGLFSSEAVALNH---------MLDAPLEFFTHEREVHSFEDGND 198


>UniRef50_C7LYW6 CRISPR-associated protein Cas5 family n=1 Tax=Acidimicrobium
           ferrooxidans DSM 10331 RepID=C7LYW6_ACIFD
          Length = 253

 Score =  165 bits (417), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 74/238 (31%), Positives = 95/238 (39%), Gaps = 41/238 (17%)

Query: 2   RSYLILRLAGPMQAWGQPTF-EGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
            S L LRL GP+QAWG     +  R T RFPT+SG++GLL A LG  R   ++L  L  +
Sbjct: 1   MSVLALRLGGPLQAWGSSQRLDHYRRTERFPTKSGVIGLLAAALGRPRS--AALDDLG-A 57

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHE----------------TI 104
           ++FAVR D             LRD+HT+    +D +     E                T 
Sbjct: 58  LRFAVRIDR--------PGEVLRDFHTLSSLFDDKKRFAPGEGRLPTASGGYRSAATSTQ 109

Query: 105 QTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQA 164
            T R YL DA F   L         + EL+ A+  P +  YLGRRSCP   PL LG    
Sbjct: 110 VTERFYLADACFVAGLE---GDAAQLQELDDALRTPVFPLYLGRRSCPPDKPLRLGVYDG 166

Query: 165 SDPQKALLNYEPVGGD-------IYSEESVTGHHLKFTARDEPMITLP--RQFASREW 213
                 L +      D       I  E  V          D+     P  R +  R  
Sbjct: 167 -GLIDVLASIPWQANDPAQSATSIRCELVVENPAGDVELADQARSFDPLTRSYTRRRV 223


>UniRef50_Q03C60 CRISPR-associated protein n=4 Tax=Lactobacillus RepID=Q03C60_LACC3
          Length = 236

 Score =  163 bits (413), Expect = 4e-39,   Method: Composition-based stats.
 Identities = 52/180 (28%), Positives = 80/180 (44%), Gaps = 20/180 (11%)

Query: 7   LRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVR 66
           +RL  P+Q++G       R TG +P++S ++G+L A LG QRDD  ++ AL++ + FAVR
Sbjct: 6   IRLTSPLQSYGNEAQFARRTTGDYPSKSAIIGMLAAALGYQRDD-PAINALNDLL-FAVR 63

Query: 67  CDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPHA 126
            D+            + ++ T           K      T+R+ L DA F VA+      
Sbjct: 64  VDQ--------PGQVMTEFQTAE--------WKPGTRKLTYRDLLQDAVFVVAI--GSED 105

Query: 127 TMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDIYSEES 186
              +  L +A+  PR+  YLGRR+      L + T    DP   L          Y   S
Sbjct: 106 EAWLDRLAEALRHPRFQLYLGRRANVPAGVLKIQTFAGQDPVGVLAQLPWQASRWYQRRS 165


>UniRef50_B8FDI0 CRISPR-associated protein Cas5 family n=3 Tax=Bacteria
           RepID=B8FDI0_DESAA
          Length = 240

 Score =  163 bits (413), Expect = 4e-39,   Method: Composition-based stats.
 Identities = 69/244 (28%), Positives = 98/244 (40%), Gaps = 33/244 (13%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             YL++ L  P+Q+WG  +  G R T  FPTRSG+LGLL   LG   +    L  L+   
Sbjct: 3   SRYLLMWLEAPLQSWGADSKFGRRDTLPFPTRSGVLGLLLCALGASGEQKELLARLAPYG 62

Query: 62  QFAVRCDELILDDRRVSV------TGLRDYHTVLGAREDYRGLKS--------------H 101
           Q  + C          S         LRD+H V  A  D    +                
Sbjct: 63  QTVISCAGGRPGRSGGSPEKIPRQPLLRDFHMVGSAYNDKDPWERLHIPKTNEGKPAVGG 122

Query: 102 ETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGT 161
               T+R YL DA F V L L P    +  +  +A+  P +  YLGR++C  T  ++ G 
Sbjct: 123 GAKLTYRYYLQDARFAVILELPPD---LAEDFAQALQNPVWDIYLGRKNCAPTEFVYQGV 179

Query: 162 C----QASDPQKALLNYEPVGGDIYSEESVTGHHL--KFTARDEPMITLP-RQFASREWY 214
                 A D   AL+  + +  D      V G H     T  D P+   P +++  R   
Sbjct: 180 FDSQKDAMDRAAALMEEKELMEDF---RVVDGEHPGEPITLNDVPLQFGPMKKYRDRRVT 236

Query: 215 VIKG 218
           VI+ 
Sbjct: 237 VIRN 240


>UniRef50_A8M404 CRISPR-associated protein Cas5 family n=1 Tax=Salinispora arenicola
           CNS-205 RepID=A8M404_SALAI
          Length = 238

 Score =  163 bits (412), Expect = 4e-39,   Method: Composition-based stats.
 Identities = 65/227 (28%), Positives = 98/227 (43%), Gaps = 35/227 (15%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           L+LRLAGP+Q+WG  +    R T   PT+SG++G+L A  G++R D   L  L  S+ F 
Sbjct: 2   LLLRLAGPLQSWGATSRFTHRHTQVTPTKSGVIGMLAAASGLRRTD--PLTELL-SLDFG 58

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTP 124
           VR D+            LRD+                    T R YL DA F VA+    
Sbjct: 59  VRIDQ--------PGQLLRDFQVARTLD------GRDSMPLTNRYYLSDAVFLVAI---G 101

Query: 125 HATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDIYSE 184
               ++  L ++V +P +  YLGRR+CP   P+ LG    +   +AL ++         E
Sbjct: 102 GDQALLEGLHESVRRPHFPLYLGRRACPPVAPISLGVHPGTV-DEALRDWPWQAAKRLRE 160

Query: 185 ------------ESVTGHHLKFTARDEPMITLP--RQFASREWYVIK 217
                       ++  G  +  T  D+P+   P  RQ+  R     +
Sbjct: 161 RGELTVPLEVVSDAPPGADVTETLPDQPISFDPAHRQYGWRAVVRTR 207


>UniRef50_D0MET6 CRISPR-associated protein Cas5 family n=1 Tax=Rhodothermus marinus
           DSM 4252 RepID=D0MET6_RHOM4
          Length = 252

 Score =  162 bits (410), Expect = 8e-39,   Method: Composition-based stats.
 Identities = 59/234 (25%), Positives = 97/234 (41%), Gaps = 27/234 (11%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L+LR   P+ ++G P  +       +P  S + GLL   LG    +T+ L+ L E +
Sbjct: 1   MEILLLRFDAPLMSFGAPIVDQYGFIQPYPALSMMTGLLANALGYTHAETARLERLQERL 60

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGARE---DYRGLKSHETIQTW----------- 107
           ++AVR D             LRD+ TV  ++    D R   +  T++T            
Sbjct: 61  RYAVREDRR--------GQQLRDFQTVDLSQPFLHDERAWTTRGTLETRQGGTASLGIHI 112

Query: 108 --REYLCDASFTVALWLT-PHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQA 164
             R+Y  DA +TVAL L  P     +++LE+A+  P    ++GR+ C    PLF+G  +A
Sbjct: 113 RLRDYWADAVYTVALTLDPPDEPPTLADLEQALRFPARPLFIGRKPCLPAAPLFIGRVEA 172

Query: 165 SDPQKALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKG 218
           +D   AL    P+       +              P+  + R+   R     + 
Sbjct: 173 ADLLDAL-RRAPLDARADRADFYRVWWETGPDDPPPVEGI-RENLRRPVTDRRD 224


>UniRef50_B8GIV3 CRISPR-associated protein Cas5 family n=1 Tax=Methanosphaerula
           palustris E1-9c RepID=B8GIV3_METPE
          Length = 257

 Score =  162 bits (410), Expect = 9e-39,   Method: Composition-based stats.
 Identities = 63/194 (32%), Positives = 84/194 (43%), Gaps = 22/194 (11%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             YL   L G M +WG       RPT   PTRS +LGLL A LGI+RD+   L AL+ + 
Sbjct: 4   PEYLTFSLYGMMASWGDIAVGEYRPTADHPTRSAVLGLLAAALGIRRDEEERLAALTRAY 63

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKS-------------HETIQTWR 108
           + A+R D             LRDYHT        +G +                TI + R
Sbjct: 64  KVAIRVD--------APGMLLRDYHTTQVPSAAKKGRQYLTRKDELAAPREVLNTILSTR 115

Query: 109 EYLCDASFTVALWLTPHATM-VISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDP 167
           +Y CDA + V +W    A    +  L + +  P +T YLGR+SCPL  P+      A D 
Sbjct: 116 DYRCDAVYRVYIWCRDTAPPYSLKTLAEHLQHPVFTLYLGRKSCPLALPVNPEVKTAPDL 175

Query: 168 QKALLNYEPVGGDI 181
             AL     +    
Sbjct: 176 LTALSEEREIELRF 189


>UniRef50_D1CAJ0 CRISPR-associated protein Cas5 family n=1 Tax=Sphaerobacter
           thermophilus DSM 20745 RepID=D1CAJ0_SPHTD
          Length = 245

 Score =  160 bits (404), Expect = 4e-38,   Method: Composition-based stats.
 Identities = 65/238 (27%), Positives = 97/238 (40%), Gaps = 40/238 (16%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            S L+LRL GPMQAWG  +    R TG  P++SG++GLL A LG  R   + +  L+  +
Sbjct: 1   MSTLLLRLTGPMQAWGTQSRFSWRDTGLEPSKSGVIGLLCAALGRPRS--APVDDLAR-L 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLG-AREDYRG-------LKSHETIQTWREYLCD 113
           +  VR D           T   D+HT  G  R    G         +     + R YL D
Sbjct: 58  RMGVRVDR--------EGTMHVDFHTAGGWHRRAEAGYGVPDPSGTARRPQISRRFYLAD 109

Query: 114 ASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDP------ 167
           A F V L        ++  L++A+  PR+  +LGR+S     P+ L       P      
Sbjct: 110 ADFLVGLE---GDEELLVLLDRALAAPRWQLFLGRKSFVPAAPVRLPDTPPWGPGLRPEP 166

Query: 168 -QKALLNYEPVGGDIYSEESVTGHHLKF-----------TARDEPMITLPRQFASREW 213
            + AL  Y  +G  +    +     L+               D P+    R+F++R  
Sbjct: 167 LETALRTYPWLGYQLPHPRADAPDRLRLVLDAEGDDAADIRMDVPISFAERRFSTRAV 224


>UniRef50_Q1J367 CRISPR-associated protein, CT1976 n=1 Tax=Deinococcus geothermalis
           DSM 11300 RepID=Q1J367_DEIGD
          Length = 232

 Score =  159 bits (402), Expect = 8e-38,   Method: Composition-based stats.
 Identities = 60/229 (26%), Positives = 91/229 (39%), Gaps = 25/229 (10%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+LRL  PMQAWG  +    R T   P++SG+LGL  A LGI R D+    A    +
Sbjct: 1   MATLLLRLVAPMQAWGTRSRFDDRDTEAEPSKSGVLGLCAAALGIDRADSVEHLA---RL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
            F VR D   +           DYHT         G     T  T R YL DA+F   L 
Sbjct: 58  AFGVRVDREGVAG--------TDYHTAQL----RPGNPRTRTDVTRRAYLADAAFWAGLE 105

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGG-- 179
                  ++++L+ A+  P +   LGR++ P + P+  G         AL     +    
Sbjct: 106 ---GDAGLLTDLDAALHNPHWPLSLGRKAFPPSLPICAGPPLEVSLWDALRTAPSLRWRD 162

Query: 180 -----DIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVS 223
                 +  +       L+  A       +P    +R  Y+ +  + V+
Sbjct: 163 DDEPYRLVLDREAVPQPLRAAASPSRRQDVPDGPFARRRYLSRDVLTVT 211


>UniRef50_Q0AA33 CRISPR-associated protein Cas5 family n=2 Tax=Gammaproteobacteria
           RepID=Q0AA33_ALHEH
          Length = 242

 Score =  159 bits (401), Expect = 9e-38,   Method: Composition-based stats.
 Identities = 56/211 (26%), Positives = 78/211 (36%), Gaps = 24/211 (11%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           LILRL  P+ ++G    +   PT RFP RS L G+L   LG    DT +L +L   + +A
Sbjct: 4   LILRLDAPLMSFGGVLVDQHNPTDRFPGRSMLTGMLANALGWHHQDTEALNSLQARISYA 63

Query: 65  VRCDELILDDRRVSVTGLRDYHTV--------------LGAREDYRGLK-SHETIQTWRE 109
            R D        V    LRDY TV               GA E   G        Q  R 
Sbjct: 64  ARWD--------VPPEPLRDYQTVDLGQTHLANPGWTTRGAPEHREGGTAKRGIHQRDRH 115

Query: 110 YLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQK 169
           Y  +   TVA+ + P    V + L  A+  P    ++GR++C    P+ L   ++ D   
Sbjct: 116 YWANGVMTVAVTVPPGEPNV-ATLAAALRHPARPLFIGRKACLPAAPVLLRVRESDDAYH 174

Query: 170 ALLNYEPVGGDIYSEESVTGHHLKFTARDEP 200
            L +                     T     
Sbjct: 175 VLASEPRDPRAAADTRFFEACWPPGTTAPAT 205


>UniRef50_Q2FNU0 CRISPR-associated protein, CT1976 n=1 Tax=Methanospirillum hungatei
           JF-1 RepID=Q2FNU0_METHJ
          Length = 225

 Score =  153 bits (386), Expect = 5e-36,   Method: Composition-based stats.
 Identities = 52/210 (24%), Positives = 81/210 (38%), Gaps = 38/210 (18%)

Query: 35  GLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLG---- 90
            +LG++ A LGI+RDD  +   L     F+V   +            ++D+HT+      
Sbjct: 15  AVLGMVAAALGIRRDDEEAQNRLQAGYGFSVMVLQ--------PGIMIQDFHTIQSVHSS 66

Query: 91  ---------AREDYRGLKSHETIQTWREYLCDASFTVALWLT--PHATMVISELEKAVLK 139
                     R D   L   ETI + REYLCD      +W+     A   + E+  +   
Sbjct: 67  SLKKMNHVMTRRDEMNLGDSETILSRREYLCDHVSVACVWIRDAESAQFSLEEIAASFRN 126

Query: 140 PRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNY-----------EPVGGDIYSEESV- 187
           P +  YLGR+SCP   P+     QA   + AL+ +            P    +Y E+ + 
Sbjct: 127 PVFCLYLGRKSCPPALPVHARVIQADSLKSALVQHIEGFDLLNGFRVPDRVSLYFEDGID 186

Query: 188 ---TGHHLKFTARDEPMITLPRQFASREWY 214
                  +    RD  +     QF+ R  Y
Sbjct: 187 IGFDDPVMVMKRRDNILSRSRWQFSDRNEY 216


>UniRef50_B4TTX2 CRISPR-associated protein Cas5 n=15 Tax=Enterobacteriaceae
           RepID=B4TTX2_SALSV
          Length = 241

 Score =  152 bits (384), Expect = 8e-36,   Method: Composition-based stats.
 Identities = 62/177 (35%), Positives = 85/177 (48%), Gaps = 19/177 (10%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M+ YL+ +L  P+ +WG+      R +   PTRS LLGLL A LGI+RD+ + L   +  
Sbjct: 1   MKEYLVFQLYAPLASWGEEASGEIRHSATVPTRSALLGLLAAALGIRRDEEARLNNFNRH 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL------------KSHETIQTWR 108
              AV                LRDYHTV   RE+ +                  T+ + R
Sbjct: 61  YHLAVHA-------LASQDRWLRDYHTVSAPRENKKYRYYTRRDELTLAPDEVGTLISQR 113

Query: 109 EYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQAS 165
           EY CD  + VA+  TP A   +SEL +A+L P +  YLGR+SCPL  PL       +
Sbjct: 114 EYRCDGYWHVAISATPDAPHSLSELREALLTPHFPLYLGRKSCPLALPLAARLMTGT 170


>UniRef50_A9HLC6 CRISPR-associated protein Cas5 family n=11 Tax=Acetobacteraceae
           RepID=A9HLC6_GLUDA
          Length = 260

 Score =  151 bits (382), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 56/191 (29%), Positives = 78/191 (40%), Gaps = 21/191 (10%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M  +L   +  PM ++G       R     P RS +LGL+ ACLG+ RDD  +  AL+  
Sbjct: 1   MGQFLTFAMVAPMASFGAIAVGERRDGWDRPARSAVLGLMAACLGLTRDDEDAQAALAAD 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLG--AREDYRGLKSHE----------TIQTWR 108
              A+ C              L DYHT     AR ++R     E          TI + R
Sbjct: 61  YGLAILC--------HAPGKLLTDYHTAQAAPARRNWRPATRAEELAASPGDLATILSRR 112

Query: 109 EYLCDASFTVALWLTPH-ATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDP 167
           +Y        A+W +   A   +  L+ A+ +P +TP LGRRSCP   PL          
Sbjct: 113 DYRMGTWHLGAVWTSGKTARWSLEALQAAMREPVFTPSLGRRSCPAGLPLAPSVTDGVSA 172

Query: 168 QKALLNYEPVG 178
              LL+    G
Sbjct: 173 AAVLLDRHRNG 183


>UniRef50_Q0BSC7 Putative uncharacterized protein n=1 Tax=Granulibacter bethesdensis
           CGDNIH1 RepID=Q0BSC7_GRABC
          Length = 225

 Score =  148 bits (374), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 65/231 (28%), Positives = 98/231 (42%), Gaps = 43/231 (18%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRD-DTSSLQALSESVQ 62
           +L+  LA  + + G+      R +  +PTRS ++GL+GA LGI+RD D S+L  LS  V 
Sbjct: 6   FLVFGLAASLGSMGELAGHERRGSLIWPTRSAIIGLMGAALGIERDGDFSALDVLSIDVA 65

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLG--------------AREDYRGLKSHETIQTWR 108
                          +   LRDYHT+                A  D RG     T  T R
Sbjct: 66  I------------FDAGAPLRDYHTIETIPSAAAKNPNSRPEALRDARGRT--NTAITHR 111

Query: 109 EYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQ 168
           +Y     + +A+         +  +  A+L+P +T Y+GR+SCPL  P      +A   +
Sbjct: 112 DYRTSVFYGIAVRGAG-----LERIVAALLEPHFTLYVGRKSCPLAAPTGAKIVEAVSAE 166

Query: 169 KALLNYEPVGGDIYSEESVTGHHLKF------TARDEPMITLPRQFASREW 213
            AL   E +   ++ +ESV  H L           D P+      FA+R  
Sbjct: 167 AAL---EHLKAPLWRKESVKAHLLVTDDPEGEVVTDVPLDRSSWHFATRRV 214


>UniRef50_UPI0001B51C2B CRISPR-associated Cas5 family protein n=1 Tax=Streptomyces
           viridochromogenes DSM 40736 RepID=UPI0001B51C2B
          Length = 278

 Score =  148 bits (373), Expect = 2e-34,   Method: Composition-based stats.
 Identities = 68/272 (25%), Positives = 98/272 (36%), Gaps = 74/272 (27%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M S L+LRLAGP+Q+WG       R T   PT+SG+ GL+ A LG+ R D   L AL++ 
Sbjct: 1   MTSVLLLRLAGPLQSWGALARFDRRDTLNRPTKSGVTGLVAAALGLDRAD--DLGALTD- 57

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGA-------------REDYRGLKSHET---- 103
           ++FAVR D           T +RD+H V                R   +   + ET    
Sbjct: 58  LRFAVRADR--------PGTAVRDFHIVGSGTYPLRPRDLITDHRRAEKAAAALETSTGP 109

Query: 104 --------------------------------------IQTWREYLCDASFTVALWLTPH 125
                                                 + T R YL DA+F  A+     
Sbjct: 110 VFGHLAARSVTKWYGAPKEIAPDPKTGVLLAGNTTRDAMMTTRWYLADAAFVAAVE--HP 167

Query: 126 ATMVISELEKAVLKPRYTPYLGRRSCPL----THPLFLGTCQASDPQKALL--NYEPVGG 179
              ++  +  AV  P+   +LGR+SCP     +  +  GT +      ALL     P   
Sbjct: 168 DQNLLHRISHAVEHPKRLLWLGRKSCPPSGTISGGVHPGTAETILTTTALLPNATSPQPW 227

Query: 180 DIYSEESVTGHHLKFTARDEPMITLPRQFASR 211
                   T    + T +        R   +R
Sbjct: 228 AWIEAAPGTPGAAQRTDQPVTYHPEHRTHTAR 259


>UniRef50_B8IMR2 CRISPR-associated protein Cas5 family n=1 Tax=Methylobacterium
           nodulans ORS 2060 RepID=B8IMR2_METNO
          Length = 273

 Score =  143 bits (361), Expect = 4e-33,   Method: Composition-based stats.
 Identities = 51/187 (27%), Positives = 70/187 (37%), Gaps = 23/187 (12%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M + L+  L  P    G       R +   P RS +LGL+   LGI R D +   AL   
Sbjct: 1   MPAGLVFTLYAPFAGMGDVAVGEERGSFDRPARSAVLGLVAGALGIDRADEAGHAALDRG 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTV----------LGAREDYRGLKSHETIQTWREY 110
            + A+R         R     + DYHTV             R +   +    T+ + R Y
Sbjct: 61  YRLALRL--------RTPGCLVEDYHTVQAPPVDRKARWATRREALAVAGLNTLVSRRAY 112

Query: 111 LCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFL----GTCQASD 166
             D    V L +          L  A+ +P + PYLGR+SCPL  PL      G  +   
Sbjct: 113 RADPIVDVVL-IHVDEGPTPEALATALRRPTFAPYLGRKSCPLGLPLRPLWAEGVTRVGS 171

Query: 167 PQKALLN 173
              AL  
Sbjct: 172 LLAALDE 178


>UniRef50_C5V9N1 CRISPR-associated protein Cas5 n=1 Tax=Corynebacterium matruchotii
           ATCC 14266 RepID=C5V9N1_9CORY
          Length = 223

 Score =  141 bits (356), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 58/234 (24%), Positives = 89/234 (38%), Gaps = 41/234 (17%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTR-PTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE 59
           M   L +RLAGP+Q+W  P   G    T   PTRSGL+GLL    G  R +         
Sbjct: 1   MTEALYIRLAGPLQSWAGPAITGNFVRTEPRPTRSGLVGLLAGACGYGRGEYPEWLT--- 57

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTV----------------LGAREDYRGLKSHE- 102
            + F +R D           T + D+HT+                +G R   + L S   
Sbjct: 58  QLHFQIREDNR--------GTLVDDFHTINPRDTEEEFRSRLLLAMGQRPTKKLLNSTPD 109

Query: 103 ----TIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLF 158
               T  T R Y+ D  F V +         +  L + + +P +  YLGR++   + P +
Sbjct: 110 GQGLTAITERTYIADGEFIVQIKAGSREHQEL--LAEKLQQPHFVTYLGRKAFAPSFPFY 167

Query: 159 LGTCQASDPQKALLNYEPVGGDIYSE--ESVTGHHLKFTARDEPMITLPRQFAS 210
           LG    + P   L     VGG+   +           +T    P++    Q+ +
Sbjct: 168 LG----AGPDDTLARIPTVGGEEPKKILRFYALDDYGYTTTTVPVVKDRNQWLT 217


>UniRef50_B6B783 CRISPR-associated protein Cas5, Ecoli subtype n=1
           Tax=Rhodobacterales bacterium Y4I RepID=B6B783_9RHOB
          Length = 232

 Score =  141 bits (356), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 59/205 (28%), Positives = 81/205 (39%), Gaps = 32/205 (15%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRD-DTSSLQALSE 59
           M  YLI +L   + A G+      R +   P RS ++G LGA +G++RD D S L AL  
Sbjct: 1   MPEYLIFQLVAAIGAMGEFGGHDRRGSLTLPGRSAVIGTLGAAMGLRRDADFSGLDALGV 60

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDY------------RGLKSHETIQTW 107
           +V                     RDYHTV                      +   T  T 
Sbjct: 61  AVA------------SFGKTAPFRDYHTVQTVPSAAVKRPQSRPQALRDAGRKVNTTLTS 108

Query: 108 REYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDP 167
           R+Y  D  F VA+W        ++EL  A+  P +  +LGR+SCPL+ P       A+ P
Sbjct: 109 RDYRADCVFGVAIWGEG-----LAELASALSAPVFQTFLGRKSCPLSAPFDPQIVAAATP 163

Query: 168 QKAL--LNYEPVGGDIYSEESVTGH 190
             AL  L   P  G    +  V   
Sbjct: 164 SAALSQLRLPPWIGAREMDMIVADE 188


>UniRef50_C2KP44 Putative uncharacterized protein n=1 Tax=Mobiluncus mulieris ATCC
           35243 RepID=C2KP44_9ACTO
          Length = 245

 Score =  137 bits (346), Expect = 2e-31,   Method: Composition-based stats.
 Identities = 55/184 (29%), Positives = 76/184 (41%), Gaps = 23/184 (12%)

Query: 1   MRSYLILRLAGPMQAW-GQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE 59
           M S   +RLAGP+Q+W G         T  +PTR  L GL+ ACLG  R          +
Sbjct: 1   MTSV-YIRLAGPLQSWAGAKVSGNISHTQDYPTRGSLEGLVAACLGCPRGKYPLW---FQ 56

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHT---------VLGAREDYRGLK-----SHETIQ 105
            +QFAVR D            G+RD            + G R   RGL        +T  
Sbjct: 57  DLQFAVRVDSPGRICDDYQTIGVRDEDMQVATRLLTLLTGKRATNRGLAFIPDAQGKTTI 116

Query: 106 TWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQAS 165
             R  L DA F V +    H    + +L++A+  P +  YLGR++     P +LG  + S
Sbjct: 117 VRRTLLADAEFIVQIQCEGH----LEQLDQAISDPTFVSYLGRKAFAPGFPFYLGIGEDS 172

Query: 166 DPQK 169
               
Sbjct: 173 AIDT 176


>UniRef50_B6IWM3 CRISPR-associated protein, CT1976 family n=1 Tax=Rhodospirillum
           centenum SW RepID=B6IWM3_RHOCS
          Length = 280

 Score =  137 bits (345), Expect = 3e-31,   Method: Composition-based stats.
 Identities = 57/194 (29%), Positives = 82/194 (42%), Gaps = 28/194 (14%)

Query: 3   SYLILRLAGPMQAWGQPTFEG----TRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALS 58
           ++L   LA P  AWG  +        + T   P+RS L GLLGA LG++R   + L  LS
Sbjct: 6   AHLCFTLAAPYGAWGAASQSSATTAWKATELDPSRSALTGLLGAALGLER---AHLGRLS 62

Query: 59  ESVQFAVRCDELILDDRRVSVTGLRDYHTVLGA---------------REDYRGLKSHET 103
           E+++FAVR       D +       DYHT+  A               R    G K    
Sbjct: 63  EALRFAVRTGIRPTRDPQP------DYHTISRAHRPEGREHWSRFEELRPALAGGKQEGA 116

Query: 104 IQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQ 163
           + + REY     +TVA+     A + +  L +A+  P +  Y GR++C L  P       
Sbjct: 117 LLSRREYWSLGLWTVAVATLNPAGVPLDRLAQALRTPHWPLYAGRKACTLGLPPDPEVRT 176

Query: 164 ASDPQKALLNYEPV 177
              P   LL+Y   
Sbjct: 177 GPGPLSVLLDYGWP 190


>UniRef50_B5GY62 Crispr-associated protein (Fragment) n=1 Tax=Streptomyces
           clavuligerus ATCC 27064 RepID=B5GY62_STRCL
          Length = 260

 Score =  135 bits (341), Expect = 9e-31,   Method: Composition-based stats.
 Identities = 61/186 (32%), Positives = 84/186 (45%), Gaps = 28/186 (15%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
            L+LRLAGP+Q+WG  +   +R TG  PT+SG++GLL A     R   + ++ L  +++ 
Sbjct: 85  VLLLRLAGPLQSWGSASAFNSRQTGAEPTKSGVIGLLAAA--DGRARGACIEDL-RALRL 141

Query: 64  AVRCDELILDDRRVSVTGLRDYHTVLGARE-------------DYRGLKSHETIQTWREY 110
            VR D         S T LRDYHT    R                    +  T  T R Y
Sbjct: 142 GVRVDR--------SGTLLRDYHTASDHRGRPLAQAGVGAKGTQRPTSPAKYTQVTTRYY 193

Query: 111 LCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKA 170
           L DA F  AL        ++  L++AV  P +   LGRRSC  + PL LG    S   + 
Sbjct: 194 LQDAVFLAALA---GPRALLDRLDRAVRAPAFPLALGRRSCVPSLPLALGVHPGS-LGEV 249

Query: 171 LLNYEP 176
           L  +  
Sbjct: 250 LSTHPW 255


>UniRef50_C2GEY8 CRISPR-associated protein n=1 Tax=Corynebacterium glucuronolyticum
           ATCC 51866 RepID=C2GEY8_9CORY
          Length = 242

 Score =  132 bits (332), Expect = 1e-29,   Method: Composition-based stats.
 Identities = 50/189 (26%), Positives = 80/189 (42%), Gaps = 37/189 (19%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTR-PTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE 59
           M S   +RL+GP+Q+W   +  G    T   PT +GL GLL   LG +RD+   +     
Sbjct: 1   MPSSTFIRLSGPIQSWAGQSVSGNFIRTNPIPTLTGLRGLLAGALGARRDE---IPEWIS 57

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDY---------RGLKSHET------- 103
            V+F+VR D+        + + + D+ T+    E++         +G+K+          
Sbjct: 58  KVRFSVREDQ--------TGSFVDDFQTIGSREEEWDFRRRIAILQGMKARSIKQLSFKP 109

Query: 104 -----IQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLF 158
                    R YL +A F V +    H      E++ A   P +  YLGR++ P   P +
Sbjct: 110 AVGANAVVRRTYLSEAEFIVRVTDERHT----EEIDHAFSSPVFATYLGRKAFPAAFPFY 165

Query: 159 LGTCQASDP 167
           LGT      
Sbjct: 166 LGTGNEDVL 174


>UniRef50_Q2RXJ5 CRISPR-associated protein, Cas5e family n=5 Tax=Proteobacteria
           RepID=Q2RXJ5_RHORT
          Length = 249

 Score =  132 bits (331), Expect = 1e-29,   Method: Composition-based stats.
 Identities = 51/209 (24%), Positives = 83/209 (39%), Gaps = 8/209 (3%)

Query: 1   MRS--YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALS 58
           M    +LI+ L  P+ A+G    +    T  FP  S L GL    LG +R +    Q L 
Sbjct: 1   MPEHRWLIVHLEAPLLAFGGVAIDNVGVTRDFPAASMLTGLFANALGWRRTEWERHQRLQ 60

Query: 59  ESVQFAVRCDE-----LILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCD 113
           + + FA R +      ++ D +   ++      T  G  E   G       +  R+Y  D
Sbjct: 61  DRLIFAARRERENPTGVLTDTQNAKLSKTERGWTTWGEPEGRDGASYGAPHRRRRDYHGD 120

Query: 114 ASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGT-CQASDPQKALL 172
           AS  VAL L       + +L  A+ +P    ++GR+SC  + PL       A+   +AL 
Sbjct: 121 ASVVVALRLDAAEEPALDDLAAALDRPARPLFIGRKSCVPSRPLRGKEFVVAATAYQALQ 180

Query: 173 NYEPVGGDIYSEESVTGHHLKFTARDEPM 201
                G D   + +       +   + P+
Sbjct: 181 ALRSDGNDRQRDGAAAERRAVWPVGEGPV 209


>UniRef50_B5F422 CRISPR-associated protein Cas5 n=59 Tax=Enterobacteriaceae
           RepID=B5F422_SALA4
          Length = 248

 Score =  130 bits (328), Expect = 3e-29,   Method: Composition-based stats.
 Identities = 53/161 (32%), Positives = 76/161 (47%), Gaps = 19/161 (11%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M  YL+ +L GPM +WG       R +   P+RS LLGLL A LGI+RD+   L A +  
Sbjct: 1   MSQYLVFQLHGPMASWGVDAPGEVRHSHELPSRSALLGLLAAALGIRRDEEERLNAFNRH 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAR--EDYRGLKSHE---------TIQTWRE 109
            QF        L     +    RDYHTV   +     R     E          + + R+
Sbjct: 61  YQF--------LLCASGNPRWARDYHTVQMPKEVRKARYFSRREELQDPELLSALISRRD 112

Query: 110 YLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRS 150
           Y  DA + +A+  TP A   +++L+ A+  P +  YLGR+S
Sbjct: 113 YYTDAWWMIAVSATPDAPYTLAQLQAALQHPVFPLYLGRKS 153


>UniRef50_Q6NEQ9 Putative uncharacterized protein n=1 Tax=Corynebacterium
           diphtheriae RepID=Q6NEQ9_CORDI
          Length = 242

 Score =  129 bits (324), Expect = 8e-29,   Method: Composition-based stats.
 Identities = 49/184 (26%), Positives = 76/184 (41%), Gaps = 22/184 (11%)

Query: 1   MRSYLILRLAGPMQAW-GQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE 59
           M     +RL+GP+Q+W G         T   PT S L GLL   LG +R +  +     +
Sbjct: 1   MIESAYIRLSGPLQSWAGSVVTGNIVRTEPRPTFSSLRGLLAGALGARRGEWPNWL---D 57

Query: 60  SVQFAVRCDE-LILDDRRVSVTGLRDYHTVLGAREDYRGLKSH-------------ETIQ 105
            V+F VR D   I+ +   ++  L +  T        +G K++              T  
Sbjct: 58  DVEFWVREDRKPIVVNEFQTINPLPEVETFRKRLLIAQGRKANSAKALTFTPDAQGGTSI 117

Query: 106 TWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQAS 165
             R YL D  + V +  + H    + E+E A   P +  YLGR++     P +LG   A 
Sbjct: 118 VNRTYLADGEYLVRVTSSTH----MDEIENAFSSPAFVTYLGRKAFYAEFPFYLGRGSAD 173

Query: 166 DPQK 169
             +K
Sbjct: 174 AFEK 177


>UniRef50_C0W6U0 CRISPR-associated Cas5 family protein n=1 Tax=Actinomyces
           urogenitalis DSM 15434 RepID=C0W6U0_9ACTO
          Length = 201

 Score =  122 bits (305), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 45/168 (26%), Positives = 67/168 (39%), Gaps = 21/168 (12%)

Query: 39  LLGACLGIQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL 98
           +L A +G +R D   ++ L  S++F VR D+          T LRD+HT           
Sbjct: 1   MLAAAVGRRRTD--PIEDLL-SLRFGVRKDQ--------PGTVLRDFHTARTLD------ 43

Query: 99  KSHETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLF 158
                  + R YL DA +  A+        ++  L+ AV  P +  YLGRRSCP + PL 
Sbjct: 44  GKQSMPLSERYYLADAVYLAAIE---GEKTLLEGLDVAVRHPVFPLYLGRRSCPPSQPLS 100

Query: 159 LGTCQASDPQKALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPR 206
           LG   AS   +AL +      D +          +       +    R
Sbjct: 101 LGIRHAS-LLQALTDEPWQAADWFRLRQDNSFRAEIVIDAASLAPDER 147


>UniRef50_B6XT64 Putative uncharacterized protein n=2 Tax=Bifidobacterium
           RepID=B6XT64_9BIFI
          Length = 212

 Score =  119 bits (298), Expect = 8e-26,   Method: Composition-based stats.
 Identities = 49/190 (25%), Positives = 76/190 (40%), Gaps = 28/190 (14%)

Query: 39  LLGACLGIQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLG-AREDYRG 97
           +L +  G  R+D   ++ L   + F VR ++            +RD  T     R+    
Sbjct: 1   MLASAQGRTRED--PIEDLL-GISFGVRVEQR--------GRVIRDLQTEKSLTRKRNSR 49

Query: 98  LKSHETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPL 157
               E   T+R YL DA F VAL        V+  L++A+  P++  YLGRRSCP  +PL
Sbjct: 50  KFDKEMPLTYRYYLADACFLVALGA---DRSVLEMLDEAIHSPKWPLYLGRRSCPPNYPL 106

Query: 158 FLGTCQASDPQKALLNYEPVGGDIYSEESVTGHHLKF-----------TARDEPMITLP- 205
            LG     +  +  LN E      +         L+            T  D P+     
Sbjct: 107 SLGIHDEYEDIRQALNSETWHASEWYRRRYRYPDLEIVCDAEKGENITTQSDLPLSFSRE 166

Query: 206 -RQFASREWY 214
            R++A+R  +
Sbjct: 167 GRRYANRAVH 176


>UniRef50_B8IJS9 CRISPR-associated protein Cas5 family n=1 Tax=Methylobacterium
           nodulans ORS 2060 RepID=B8IJS9_METNO
          Length = 253

 Score =  107 bits (267), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 47/178 (26%), Positives = 72/178 (40%), Gaps = 7/178 (3%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           MR +L+L L  P+QAWG    +   P   FP  + + GL+   LG  R D   L+AL E 
Sbjct: 1   MREHLLLLLEAPLQAWGGVLVDAYGPVDEFPAATLVGGLVANALGYDRADWQRLEALQER 60

Query: 61  VQFA---VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKS--HETIQTWREYLCDAS 115
           +      +R    I D++   +       T  G  E   G         + +R+Y  D  
Sbjct: 61  LVVGAAVLRRGSTITDNQNAKLEKGDVGWTTRGRPEGRGGGAEAYKSPHRRFRDYHADTL 120

Query: 116 FTVALWLTPHAT-MVISELEKAVLKPRYTPYLGRRSCPLTH-PLFLGTCQASDPQKAL 171
             VAL L P      +  +   +  P    +LGR+ C  +   ++    +A    KAL
Sbjct: 121 ALVALRLDPEDEKPDLDAIAHTLEWPERPLFLGRKPCLPSRSIVWPERMRAETLLKAL 178


>UniRef50_A0LM54 Putative uncharacterized protein n=1 Tax=Syntrophobacter
           fumaroxidans MPOB RepID=A0LM54_SYNFM
          Length = 210

 Score = 83.9 bits (206), Expect = 4e-15,   Method: Composition-based stats.
 Identities = 39/196 (19%), Positives = 71/196 (36%), Gaps = 39/196 (19%)

Query: 46  IQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQ 105
           ++R D ++L       +  VR D              +D+ T         G      + 
Sbjct: 26  LRRGDLAAL-------RMGVRVDR--------EGLLRKDFQTAQNVIVAGGGSVGD--LV 68

Query: 106 TWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFL--GTCQ 163
           + R +L DA+F V L       M++  L  ++  PR+  +LGR+S   + P ++  G  +
Sbjct: 69  SNRYFLSDAAFLVGLE---GDFMLLHRLHASLAHPRWPVFLGRKSYVPSIPPYIKNGLLE 125

Query: 164 ASDPQKALLNYEP---VGGDIYSEESVTGHH--------------LKFTARDEPMITLPR 206
            ++   AL ++ P   V       + V                       RD+PM     
Sbjct: 126 GAELMSALASFTPLISVEELAARRKRVESGRRVERTRFVLESASPTHEIRRDQPMSFALG 185

Query: 207 QFASREWYVIKGGMDV 222
           Q    + +V+   +DV
Sbjct: 186 QRVFHDRFVVTEYLDV 201


>UniRef50_UPI0000F51765 hypothetical protein Faci_00030 n=1 Tax=Ferroplasma acidarmanus
           fer1 RepID=UPI0000F51765
          Length = 237

 Score = 55.0 bits (131), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 21/149 (14%), Positives = 52/149 (34%), Gaps = 21/149 (14%)

Query: 1   MRSYLILRL--AGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALS 58
           M+   ++R+   G + ++  P       T   P ++ ++G++ A +G  RDD   +++L 
Sbjct: 1   MKEIKLIRINAYGIINSFRIPLHMTIHDTLDLPVKTHIIGMIAAAMGYLRDDKEKIESLY 60

Query: 59  ESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV 118
           ++    +           + +   +     +         K++ TI     Y+       
Sbjct: 61  KNTSIGIYGTSYSKFYDLIRIYKYKGKEVEVSLVNRQINYKNNYTI-----YI------- 108

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLG 147
                      + E+   +  P +   LG
Sbjct: 109 -------ENNNLEEIYNFLKNPVFALSLG 130


>UniRef50_B1I5P1 CRISPR-associated protein Cas5 n=2 Tax=Clostridia
           RepID=B1I5P1_DESAP
          Length = 238

 Score = 50.0 bits (118), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 40/164 (24%), Positives = 62/164 (37%), Gaps = 29/164 (17%)

Query: 38  GLLGACLGIQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRG 97
           GL GA  G+   +    Q  +  ++     D L+           RD  TV+  + +   
Sbjct: 26  GLAGAARGL--AEEELWQE-ASPLR-----DLLVATLALQKPGLARDMWTVMKIKNNKLA 77

Query: 98  LKSHETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGR--------- 148
            +S      +RE L +A F +   L      +++EL++A L P Y   LGR         
Sbjct: 78  ERSPY----FREILFNARFMI---LYGGPEELLAELQQAFLDPTYPLSLGREDELIVVEE 130

Query: 149 ----RSCPLTHPLFLGTCQASDPQKALLNYEPVGGDIYSEESVT 188
                +CP   PLF GT    D Q     + P  G  +   +V 
Sbjct: 131 LGRGETCP-GAPLFSGTVIPGDLQGLRFKWVPRPGIAFEPPAVE 173


>UniRef50_Q3AA65 CRISPR-associated protein Cas5, Hmari subtype n=1
           Tax=Carboxydothermus hydrogenoformans Z-2901
           RepID=Q3AA65_CARHZ
          Length = 248

 Score = 48.8 bits (115), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 45/235 (19%), Positives = 78/235 (33%), Gaps = 33/235 (14%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGR------FPTRSGLLGLLGACLGIQRDDTSSL 54
           MR  ++  + GP              T        FP R+ L G++ A LG+ +D   SL
Sbjct: 1   MRKVIVFEIRGP------AAHFRKFYTNSSSLSYAFPARTTLAGIIAAVLGLPKDSYYSL 54

Query: 55  ---QALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAR--EDYRGLKSHETIQTWRE 109
                   +++      +++   + V    L++ +   G         L        +R 
Sbjct: 55  LTGNKAHYALRLMTPVRKIMQTVKFVRTKTLKEVNGSGGPTMIPTEIILPVRGRELIYRV 114

Query: 110 YLCDASFTVALWLTPHATMVISELEKAV-LKPRYTPYLGRRSCPLTHPL---FLGTCQAS 165
           Y                     EL K + L P++  YLGR            F GT   +
Sbjct: 115 Y-----------FYHDDPSFQEELAKQLALGPKFPVYLGRSEFLAKIDFLGVFPGTALET 163

Query: 166 DPQKALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLP-RQFASREWYVIKGG 219
           +    ++N E +  +     ++ G  L++     P    P R  AS    V + G
Sbjct: 164 NFVDTVVNLELLKDEELLFSTLHGEDLRYLKEKMPFSFNPDRSIASTASVVYEIG 218


>UniRef50_B5IGN1 CRISPR-associated protein Cas5 n=1 Tax=Aciduliprofundum boonei T469
           RepID=B5IGN1_9EURY
          Length = 236

 Score = 48.8 bits (115), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 23/150 (15%), Positives = 50/150 (33%), Gaps = 21/150 (14%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGI-QRDDTSSLQALSES 60
              L  +L     ++ +        T   P  + ++GLLG+ LG+  R+  +    L++ 
Sbjct: 1   MEVLTAKLRAISVSFRRILDFNYHRTYPLPPPTTIVGLLGSALGLSDRELWNEYNGLND- 59

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWR--EYLCDASFTV 118
           + FAV                 +D  ++   +             + R   +     +  
Sbjct: 60  ISFAVLSLR--------KPGFAKDMWSIQKIKNGR---------ISERSPYFRELLFYPE 102

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGR 148
            + +    +  +  +  A+  P Y   LGR
Sbjct: 103 YVLIFNGDSKSLECVRDALNNPEYALSLGR 132


>UniRef50_B0K553 CRISPR-associated protein Cas5, Hmari subtype n=4
           Tax=Thermoanaerobacter RepID=B0K553_THEPX
          Length = 236

 Score = 47.3 bits (111), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 29/170 (17%), Positives = 57/170 (33%), Gaps = 34/170 (20%)

Query: 16  WGQPTFEGTRPTGR------FPTRSGLLGLLGACLGIQRDD-TSSLQALSESVQFAVR-- 66
           WG+        T         P R+ + G++ A LG +RD     L A  E++  AVR  
Sbjct: 7   WGKFAHFRKFYTNSSSLTYSVPPRTTVEGMIAALLGYERDTYYEKLNA--ENLYVAVRKM 64

Query: 67  --CDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTP 124
               +++     +  T L + H      +    L   ++   +R Y+             
Sbjct: 65  SKTKKIMQSVNYIKATTLGELHFPKQHTQIPFELLISDSKIRYRFYI-----------IH 113

Query: 125 HATMVISELEKAV--LKPRYTPYLGRRSCPLTHPL--FLGTCQASDPQKA 170
               +  E+++ +    P +  Y G      + P   ++   +      A
Sbjct: 114 KDENIFREIKERLFKKAPVFPLYFG------SAPFSCYIDYVEEVTWDWA 157


>UniRef50_Q1AZD3 CRISPR-associated protein, Cas5h family n=1 Tax=Rubrobacter
           xylanophilus DSM 9941 RepID=Q1AZD3_RUBXD
          Length = 258

 Score = 46.1 bits (108), Expect = 9e-04,   Method: Composition-based stats.
 Identities = 38/190 (20%), Positives = 59/190 (31%), Gaps = 34/190 (17%)

Query: 27  TGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYH 86
           +  FP R+ L GL+   +G +RD  +   +L E  Q AV     +    +     + + H
Sbjct: 29  SYPFPPRTTLAGLIAGMMGCERDSYAEDLSL-ERCQIAVSVITPVRRVMQQVNYVMTEGH 87

Query: 87  TVLGAREDYRGLKSHETI-------------QTWREYLCDASFTVALWLTPHATMVISEL 133
                   + G      +               +R Y            T      +  L
Sbjct: 88  VWTKNTGGFDGSSGPIQVPVEWVFPEVGHRELRYRVY-----------ATHEDRGWLKRL 136

Query: 134 EKAVLK--PRYTPYLGRRSCP-------LTHPLFLGTCQASDPQKALLNYEPVGGDIYSE 184
            + +    P Y PYLG   CP             LG  +   P + +L  E V G    E
Sbjct: 137 AEILEGGVPIYPPYLGMSECPGRVEHVATLEGWGLGHREDELPVRTVLPSEAVSGPPRLE 196

Query: 185 ESVTGHHLKF 194
           E V     + 
Sbjct: 197 EGVQIVKERI 206


>UniRef50_D1N0K0 Putative uncharacterized protein n=1 Tax=Victivallis vadensis ATCC
           BAA-548 RepID=D1N0K0_9BACT
          Length = 239

 Score = 46.1 bits (108), Expect = 0.001,   Method: Composition-based stats.
 Identities = 39/242 (16%), Positives = 69/242 (28%), Gaps = 36/242 (14%)

Query: 2   RSYLILRLAGPMQAWGQP--TFEGTRPTGRFPTRSGLLGLLGACLGI--QRDDTSSLQAL 57
            S LI  LAG M  W     +       G  P    L G++GA LG    R   +     
Sbjct: 1   MSILIFELAGEMAMWRNVYESMGSYSCLGPAPGN--LAGVIGAALGFASPRSQAAEKPDA 58

Query: 58  SESVQFAVRCDELILDDRRVSVTGLRDYHTV---LGAREDYRGLKSHETIQTWR------ 108
            +   +        +    ++     D+H     +G          +   +  R      
Sbjct: 59  KQLKNWDKAGLPWPVSPELLAWEETNDFHVACRWIGKFPKRVPWNINGCKEINRSDNLRL 118

Query: 109 --EYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSC------------PLT 154
             + + D ++ VA+ L  +       +  A+ KP +   LG   C               
Sbjct: 119 QQQVILDPAYEVAVALPAYEA---ERVAAALRKPAFPLCLGASFCRAIVRNVRIEDAVPE 175

Query: 155 HPLFLGTCQASDPQKALLNYEPV--GGDIYSEESVTGHHLKFTARDEPMITLPRQFASRE 212
            P +          +A      +   G  +      G+ +  T     +I    +   R 
Sbjct: 176 SPFWAFRTDGGALGEATPFSRHIVNPGSCFERIRSDGYWIYPTPDQPGVIAA--EPLVRG 233

Query: 213 WY 214
           W 
Sbjct: 234 WV 235


>UniRef50_A3DHS3 CRISPR-associated protein Cas5 n=3 Tax=Clostridium thermocellum
           RepID=A3DHS3_CLOTH
          Length = 241

 Score = 44.6 bits (104), Expect = 0.003,   Method: Composition-based stats.
 Identities = 32/143 (22%), Positives = 51/143 (35%), Gaps = 17/143 (11%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           LI+ L     ++  P  +    T   P  S + G+ GA LG+  +D     AL+   + A
Sbjct: 4   LIVTLYAKTASFRDPGAQLYHETMSLPPPSTITGIAGAALGLSFED-----ALAFMKENA 58

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTP 124
           V        + R      +D   +    +   G  ++  I   R +L D    +      
Sbjct: 59  VMVGCNGSSEGRG-----KD---LWNYTKIKSGEITNAIII--RNFLADLKVEIFFAC-- 106

Query: 125 HATMVISELEKAVLKPRYTPYLG 147
               VI+ L  A   P Y   LG
Sbjct: 107 EKREVITRLADAFENPVYAITLG 129


>UniRef50_D0MJ68 CRISPR-associated protein Cas5 n=1 Tax=Rhodothermus marinus DSM
           4252 RepID=D0MJ68_RHOM4
          Length = 236

 Score = 43.8 bits (102), Expect = 0.004,   Method: Composition-based stats.
 Identities = 36/144 (25%), Positives = 53/144 (36%), Gaps = 21/144 (14%)

Query: 9   LAGPMQAWGQPTFE-GTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAV-- 65
           LAGP+ ++  P F  G +PT   P  S + GL+ A LG         +AL  + +F    
Sbjct: 13  LAGPVASFRYPHFLIGRQPTYPMPPPSTIYGLISAALGR----FPDPEALQFAYRFECAR 68

Query: 66  -RCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTP 124
            R D++         T  R         E  R      +    RE+L     T+ +    
Sbjct: 69  HRVDDVETIWFVQPNTATR--------GEAARKNLEATSNILPREWLVHPRLTLYVTGDE 120

Query: 125 HATMVISELEKAVLKPRYTPYLGR 148
                +  L +A   P Y   LGR
Sbjct: 121 -----LEALYRAFRSPCYILTLGR 139


>UniRef50_C9RCY2 CRISPR-associated protein Cas5, Hmari subtype n=2
           Tax=Thermoanaerobacteraceae RepID=C9RCY2_AMMDK
          Length = 266

 Score = 41.9 bits (97), Expect = 0.015,   Method: Composition-based stats.
 Identities = 43/235 (18%), Positives = 73/235 (31%), Gaps = 33/235 (14%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M +  +  L GP   + +     +  +  FP R+ L+G + A LG +RD       LSE+
Sbjct: 1   MVNVAVFDLVGPFAHFRKYYTNSSSLSYAFPPRTALMGTVAAVLGWERDSYYEKLGLSEA 60

Query: 61  VQFAV-------RCDELILDDRRVS--VTGLRDYHTVLGAREDYRGLKSHETIQT--WRE 109
            +FAV       R  + +   R     +  LR    V G +     L    T  +  +R 
Sbjct: 61  -RFAVVIKVPVRRLIQTVNYIRTKEEDLNRLRKLEAVKGTQVPLELLLPGGTASSLCFRV 119

Query: 110 YLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQK 169
           Y        A         +   L     +  +  YLG     LT  +         P  
Sbjct: 120 Y-------FAHRDDQVTRELAERLAAG--RSYFPLYLG-----LTEFIAQARLVDFKPPD 165

Query: 170 ALLN-------YEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIK 217
            ++        +  +  D      + G       R        R+      Y+ +
Sbjct: 166 EIIPAGQEVELHSVLAADYLRRPVLRGEVALNRERAPQSFGAGRKLMPPRSYIYE 220


>UniRef50_A5D0Y3 Putative uncharacterized protein n=1 Tax=Pelotomaculum
           thermopropionicum SI RepID=A5D0Y3_PELTS
          Length = 242

 Score = 41.5 bits (96), Expect = 0.021,   Method: Composition-based stats.
 Identities = 46/220 (20%), Positives = 68/220 (30%), Gaps = 21/220 (9%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
             L+  + G +  + QP    T  T  FP R  + GLL + LG+  DD +    L E   
Sbjct: 4   QVLVFSIKGSLAHFRQPDTTATHATYPFPPRPTIHGLLASVLGLDFDDEAGAAFLHEEHF 63

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETI--QTWREYLCDASFTVAL 120
             +   + +      +V      H                TI       YL         
Sbjct: 64  VGLSLLKPVR-----TVCAQMSMHGKGFTGGGGDSFNRLTTIELVVSPHYL-------VY 111

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQ----ASDPQKALLNYEP 176
           +       +   +     +  Y  YLG   C LT P+F G       A   ++ L     
Sbjct: 112 YTGSRLGELAERIRTG--QSVYHTYLGSAYC-LTFPVFHGLYPLLEVAPGEEEPLPCSSV 168

Query: 177 VGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVI 216
           V   +  E  V        AR  P   +  +F  R   VI
Sbjct: 169 VPQGVIQEILVEPGGNYAVARALPYRHVGGRFFERTLNVI 208


>UniRef50_D1A6P6 Metal dependent phosphohydrolase n=1 Tax=Thermomonospora curvata
           DSM 43183 RepID=D1A6P6_THECD
          Length = 1027

 Score = 40.8 bits (94), Expect = 0.038,   Method: Composition-based stats.
 Identities = 27/146 (18%), Positives = 42/146 (28%), Gaps = 26/146 (17%)

Query: 8   RLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVRC 67
           +L  P+ ++  P F G       P  S L G+L A  G            +E V   V  
Sbjct: 14  QLYAPVASFRDPMFPGVTRCLPVPPPSTLRGMLAAATGRP----------AEPVVLGV-- 61

Query: 68  DELILDDRRVSVTGLRDYH--TVLGAREDYRGLKSH---ETIQTWREYLCDASFTVALWL 122
                            YH     G+     G             R +L     T+ + +
Sbjct: 62  ----CAYAEGRGVDTETYHPIAADGSNPAIGGRVRPGKGGMTIRERPFLTGVHITLWVPM 117

Query: 123 TPHATMVISELEKAVLKPRYTPYLGR 148
                     +  A+ +P +   LGR
Sbjct: 118 PDG-----ERIATALRRPTWGLRLGR 138


Searching..................................................done


Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_Q46898 Uncharacterized protein ygcI n=13 Tax=Proteobact...   278   7e-74
UniRef50_B7KJ26 CRISPR-associated protein Cas5 family n=1 Tax=Cy...   223   4e-57
UniRef50_D1NTI1 CRISPR-associated protein Cas5 n=1 Tax=Bifidobac...   220   2e-56
UniRef50_D1CGD4 CRISPR-associated protein Cas5 family n=6 Tax=Ba...   211   2e-53
UniRef50_Q12YA8 CRISPR-associated protein, CT1976-like n=1 Tax=M...   209   5e-53
UniRef50_Q314I4 CRISPR-associated protein, CT1976 n=1 Tax=Desulf...   209   7e-53
UniRef50_C2BET8 CRISPR-associated protein n=2 Tax=Firmicutes Rep...   205   8e-52
UniRef50_A3EQA4 CRISPR-ssociated protein, Cas5 n=3 Tax=Bacteria ...   205   8e-52
UniRef50_B0TDU1 Crispr-associated protein cas5 n=1 Tax=Heliobact...   199   5e-50
UniRef50_B8HWH8 CRISPR-associated protein Cas5 family n=1 Tax=Cy...   199   8e-50
UniRef50_Q04QB7 Putative uncharacterized protein n=2 Tax=Leptosp...   198   1e-49
UniRef50_D0Y918 CRISPR-associated protein Cas5 family n=2 Tax=De...   198   1e-49
UniRef50_Q0W584 Putative uncharacterized protein n=1 Tax=uncultu...   197   3e-49
UniRef50_D0WFC8 CRISPR-associated protein Cas5 n=1 Tax=Slackia e...   197   3e-49
UniRef50_B4S8P8 CRISPR-associated protein Cas5 family n=8 Tax=Ba...   195   8e-49
UniRef50_A1ARH6 CRISPR-associated protein, Cas5e family n=2 Tax=...   194   3e-48
UniRef50_C9M2Y8 CRISPR-associated protein n=1 Tax=Lactobacillus ...   193   4e-48
UniRef50_Q5YRB6 Putative uncharacterized protein n=1 Tax=Nocardi...   192   9e-48
UniRef50_D2RB02 CRISPR system CASCADE complex protein CasD n=3 T...   192   9e-48
UniRef50_A8SDR7 Putative uncharacterized protein n=1 Tax=Faecali...   191   1e-47
UniRef50_B2GBJ9 Putative uncharacterized protein n=1 Tax=Lactoba...   191   2e-47
UniRef50_A7BA63 Putative uncharacterized protein n=1 Tax=Actinom...   191   2e-47
UniRef50_Q2JWC5 CRISPR-associated protein Cas5, Ecoli subtype n=...   190   3e-47
UniRef50_Q1EQS9 CRISPR-associated protein n=3 Tax=Streptomyces R...   190   3e-47
UniRef50_A5GBK2 CRISPR-associated protein Cas5 family n=2 Tax=De...   189   5e-47
UniRef50_UPI0001AF1D4C CRISPR-associated protein, CT1976 n=1 Tax...   189   7e-47
UniRef50_C7MQD6 CRISPR-associated protein Cas5 n=1 Tax=Saccharom...   189   8e-47
UniRef50_A5UR14 CRISPR-associated protein, Cas5e family n=1 Tax=...   188   1e-46
UniRef50_B1VIY0 CRISPR-associated protein n=9 Tax=Actinomycetale...   186   4e-46
UniRef50_B0S4B6 Putative uncharacterized protein n=1 Tax=Finegol...   185   7e-46
UniRef50_Q1R114 CRISPR-associated protein, CT1976 n=1 Tax=Chromo...   185   8e-46
UniRef50_A6W168 CRISPR-associated protein Cas5 family n=6 Tax=Ga...   185   1e-45
UniRef50_Q47PI7 CRISPR-associated protein, Cas5e family n=12 Tax...   184   2e-45
UniRef50_A8M404 CRISPR-associated protein Cas5 family n=1 Tax=Sa...   184   3e-45
UniRef50_D1A6Q5 CRISPR-associated protein Cas5 family n=2 Tax=Ac...   183   4e-45
UniRef50_C5SD48 CRISPR-associated protein Cas5 family n=1 Tax=Al...   182   6e-45
UniRef50_C7LYW6 CRISPR-associated protein Cas5 family n=1 Tax=Ac...   182   6e-45
UniRef50_A1SV73 CRISPR-associated protein, Cas5e family n=2 Tax=...   182   6e-45
UniRef50_Q03C60 CRISPR-associated protein n=4 Tax=Lactobacillus ...   180   3e-44
UniRef50_C8XAY4 CRISPR-associated protein Cas5 family n=2 Tax=Ac...   180   3e-44
UniRef50_A8LYZ7 CRISPR-associated protein Cas5 family n=2 Tax=Ac...   180   4e-44
UniRef50_Q2RY19 CRISPR-associated protein, Cas5e family n=1 Tax=...   179   7e-44
UniRef50_C7MTB0 CRISPR-associated protein Cas5 n=1 Tax=Saccharom...   178   1e-43
UniRef50_D2L2X8 CRISPR-associated protein Cas5 family n=1 Tax=De...   178   1e-43
UniRef50_A8ZZ17 CRISPR-associated protein Cas5 family n=1 Tax=De...   178   1e-43
UniRef50_D1CAJ0 CRISPR-associated protein Cas5 family n=1 Tax=Sp...   178   1e-43
UniRef50_Q2JH27 CRISPR-associated protein, CT1976 n=6 Tax=Actino...   176   4e-43
UniRef50_B3E5U9 CRISPR-associated protein Cas5 family n=2 Tax=De...   175   8e-43
UniRef50_D0MET6 CRISPR-associated protein Cas5 family n=1 Tax=Rh...   172   7e-42
UniRef50_Q1J367 CRISPR-associated protein, CT1976 n=1 Tax=Deinoc...   171   2e-41
UniRef50_C9M9R7 CRISPR-associated protein Cas5, Ecoli subtype n=...   170   3e-41
UniRef50_D1Y486 Crispr-associated protein Cas5 n=1 Tax=Pyramidob...   170   4e-41
UniRef50_B8IZA7 CRISPR-associated protein Cas5 family n=1 Tax=De...   169   5e-41
UniRef50_B4UE71 CRISPR-associated protein Cas5 family n=2 Tax=An...   169   6e-41
UniRef50_B8GIV3 CRISPR-associated protein Cas5 family n=1 Tax=Me...   166   4e-40
UniRef50_Q0AA33 CRISPR-associated protein Cas5 family n=2 Tax=Ga...   166   4e-40
UniRef50_B8FDI0 CRISPR-associated protein Cas5 family n=3 Tax=Ba...   166   5e-40
UniRef50_Q2FNU0 CRISPR-associated protein, CT1976 n=1 Tax=Methan...   158   9e-38
UniRef50_UPI0001B51C2B CRISPR-associated Cas5 family protein n=1...   158   2e-37
UniRef50_Q0BSC7 Putative uncharacterized protein n=1 Tax=Granuli...   157   4e-37
UniRef50_C5V9N1 CRISPR-associated protein Cas5 n=1 Tax=Corynebac...   155   9e-37
UniRef50_B4TTX2 CRISPR-associated protein Cas5 n=15 Tax=Enteroba...   153   3e-36
UniRef50_A9HLC6 CRISPR-associated protein Cas5 family n=11 Tax=A...   152   8e-36
UniRef50_B6B783 CRISPR-associated protein Cas5, Ecoli subtype n=...   150   4e-35
UniRef50_B5GY62 Crispr-associated protein (Fragment) n=1 Tax=Str...   145   7e-34
UniRef50_C2KP44 Putative uncharacterized protein n=1 Tax=Mobilun...   145   8e-34
UniRef50_B8IMR2 CRISPR-associated protein Cas5 family n=1 Tax=Me...   142   6e-33
UniRef50_Q2RXJ5 CRISPR-associated protein, Cas5e family n=5 Tax=...   142   1e-32
UniRef50_Q6NEQ9 Putative uncharacterized protein n=1 Tax=Coryneb...   138   1e-31
UniRef50_B5F422 CRISPR-associated protein Cas5 n=59 Tax=Enteroba...   136   6e-31
UniRef50_B6XT64 Putative uncharacterized protein n=2 Tax=Bifidob...   136   7e-31
UniRef50_B6IWM3 CRISPR-associated protein, CT1976 family n=1 Tax...   135   1e-30
UniRef50_C2GEY8 CRISPR-associated protein n=1 Tax=Corynebacteriu...   134   2e-30
UniRef50_C0W6U0 CRISPR-associated Cas5 family protein n=1 Tax=Ac...   133   5e-30
UniRef50_B8IJS9 CRISPR-associated protein Cas5 family n=1 Tax=Me...   129   5e-29
UniRef50_Q3AA65 CRISPR-associated protein Cas5, Hmari subtype n=...   118   1e-25
UniRef50_D1N0K0 Putative uncharacterized protein n=1 Tax=Victiva...   115   2e-24
UniRef50_A0LM54 Putative uncharacterized protein n=1 Tax=Syntrop...   103   5e-21
UniRef50_UPI0000F51765 hypothetical protein Faci_00030 n=1 Tax=F...   103   5e-21
UniRef50_B0K553 CRISPR-associated protein Cas5, Hmari subtype n=...    95   2e-18
UniRef50_B5IGN1 CRISPR-associated protein Cas5 n=1 Tax=Acidulipr...    94   3e-18
UniRef50_Q1AZD3 CRISPR-associated protein, Cas5h family n=1 Tax=...    91   3e-17
UniRef50_B1I5P1 CRISPR-associated protein Cas5 n=2 Tax=Clostridi...    78   3e-13

Sequences not found previously or not previously below threshold:

UniRef50_D1CHV1 CRISPR-associated protein Cas5 n=1 Tax=Thermobac...    63   9e-09
UniRef50_A5D0Y3 Putative uncharacterized protein n=1 Tax=Pelotom...    59   9e-08
UniRef50_A3DHS3 CRISPR-associated protein Cas5 n=3 Tax=Clostridi...    58   3e-07
UniRef50_D1B1G1 CRISPR-associated protein Cas5 n=1 Tax=Sulfurosp...    58   3e-07
UniRef50_A7ZDW7 Crispr-associated protein Cas5 n=3 Tax=Campyloba...    57   4e-07
UniRef50_A7HLK6 CRISPR-associated protein Cas5, Hmari subtype n=...    57   5e-07
UniRef50_C7P9L3 CRISPR-associated protein Cas5 n=2 Tax=Methanoca...    57   6e-07
UniRef50_D0MJ68 CRISPR-associated protein Cas5 n=1 Tax=Rhodother...    55   2e-06
UniRef50_B7R550 CRISPR-associated protein Cas5 n=1 Tax=Thermococ...    55   3e-06
UniRef50_C9RCY2 CRISPR-associated protein Cas5, Hmari subtype n=...    54   3e-06
UniRef50_B5YBH8 CRISPR-associated protein Cas5, Hmari subtype n=...    53   8e-06
UniRef50_C6QNG6 CRISPR-associated protein Cas5, Hmari subtype n=...    53   8e-06
UniRef50_O27159 Putative uncharacterized protein n=1 Tax=Methano...    53   9e-06
UniRef50_D1A6P6 Metal dependent phosphohydrolase n=1 Tax=Thermom...    52   2e-05
UniRef50_A4J1X9 CRISPR-associated protein Cas5, Hmari subtype n=...    52   2e-05
UniRef50_O57910 Putative uncharacterized protein PH0171 n=1 Tax=...    51   3e-05
UniRef50_Q2NH81 Putative uncharacterized protein n=1 Tax=Methano...    50   4e-05
UniRef50_B1LAM2 CRISPR-associated protein Cas5, Hmari subtype n=...    50   5e-05
UniRef50_D2QT47 CRISPR-associated protein Cas5 n=1 Tax=Spirosoma...    49   1e-04
UniRef50_A3XI99 Putative uncharacterized protein n=1 Tax=Leeuwen...    49   1e-04
UniRef50_C7NNV3 CRISPR-associated protein Cas5, Hmari subtype n=...    48   2e-04
UniRef50_C8PE23 CRISPR-associated protein Cas5 n=1 Tax=Campyloba...    48   2e-04
UniRef50_B9MPU1 CRISPR-associated protein Cas5, Hmari subtype n=...    47   4e-04
UniRef50_B1B9K0 Crispr-associated protein Cas5, tneap subtype n=...    47   4e-04
UniRef50_A3DKB9 CRISPR-associated protein Cas5, Hmari subtype n=...    47   5e-04
UniRef50_C8VZL1 CRISPR-associated protein Cas5 n=1 Tax=Desulfoto...    46   8e-04
UniRef50_B1I4M5 CRISPR-associated protein Cas5 family n=1 Tax=Ca...    46   8e-04
UniRef50_Q3M7D6 Fruiting body developmental protein S-like prote...    46   0.001
UniRef50_C1DUR1 Crispr-associated protein Cas5, hmari subtype n=...    46   0.001
UniRef50_A7BQN4 Protein containing DUF522 n=1 Tax=Beggiatoa sp. ...    46   0.001
UniRef50_B8CYA3 CRISPR-associated protein Cas5 n=1 Tax=Halotherm...    45   0.002
UniRef50_Q8PZD2 Putative uncharacterized protein n=1 Tax=Methano...    45   0.002
UniRef50_A1ZVP9 Crispr-associated protein Cas5, tneap subtype n=...    44   0.003
UniRef50_A8F3P0 CRISPR-associated protein Cas5, Hmari subtype n=...    44   0.004
UniRef50_A4XGC7 CRISPR-associated protein Cas5 family n=1 Tax=Ca...    43   0.008
UniRef50_D1QSA9 CRISPR-associated protein Cas5, Tneap subtype n=...    41   0.026
UniRef50_B9LWL0 CRISPR-associated protein Cas5, Hmari subtype n=...    41   0.041
UniRef50_A1HND7 CRISPR-associated protein Cas5 family n=1 Tax=Th...    40   0.063

>UniRef50_Q46898 Uncharacterized protein ygcI n=13 Tax=Proteobacteria
           RepID=YGCI_ECOLI
          Length = 224

 Score =  278 bits (712), Expect = 7e-74,   Method: Composition-based stats.
 Identities = 224/224 (100%), Positives = 224/224 (100%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES
Sbjct: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL
Sbjct: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180
           WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD
Sbjct: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180

Query: 181 IYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVSQ 224
           IYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVSQ
Sbjct: 181 IYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVSQ 224


>UniRef50_B7KJ26 CRISPR-associated protein Cas5 family n=1 Tax=Cyanothece sp. PCC
           7424 RepID=B7KJ26_CYAP7
          Length = 215

 Score =  223 bits (568), Expect = 4e-57,   Method: Composition-based stats.
 Identities = 67/228 (29%), Positives = 111/228 (48%), Gaps = 17/228 (7%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M   L+LRLAGP+Q+WG+ +    R T   PT+SG++GL+ A +GI RD+   L  L++ 
Sbjct: 1   MMKTLLLRLAGPLQSWGRGSRFDFRDTDTIPTKSGVIGLVAAAMGINRDNQVELAKLAQ- 59

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           ++  V  ++            + DYHTV+G      G      IQ++R+YLC+A F V L
Sbjct: 60  LRMGVCVEK--------EGKLVVDYHTVIGTIH-ADGKPHKAPIQSYRQYLCNAEFLVGL 110

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNY--EPVG 178
             +     +++E+E  +  P++  +LGR++CP + P+F+        + AL  Y    + 
Sbjct: 111 ESS--EYHLLNEIEHYLCFPKWELFLGRKACPPSKPIFVDLLTN-SLEDALYQYAISHLK 167

Query: 179 GDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIK--GGMDVSQ 224
              Y     +         D P+    R F++R     K     DVS+
Sbjct: 168 KGTYRLLIESKEPTGALRLDVPIDFKKRIFSARTVITPKPLEVSDVSE 215


>UniRef50_D1NTI1 CRISPR-associated protein Cas5 n=1 Tax=Bifidobacterium gallicum DSM
           20093 RepID=D1NTI1_9BIFI
          Length = 250

 Score =  220 bits (561), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 66/226 (29%), Positives = 101/226 (44%), Gaps = 28/226 (12%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            S LILRLAGPMQ+WG  +    R T   PT+S ++GLL +  G +R+D  S++ L   +
Sbjct: 1   MSVLILRLAGPMQSWGDSSRFNRRETRTEPTKSAVIGLLASAQGRRRED--SIEDLL-GL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +F VR D+            +RD+ T         G  S     T R YL DA F VA+ 
Sbjct: 58  RFGVRSDQ--------PGRIMRDFQTEKSIARKKSGEFSLTMPLTHRYYLADAKFLVAIE 109

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                  ++  L+ A+  P++  +LGRRSCP   P+ LG    ++ ++AL     +    
Sbjct: 110 ---GERSLLESLDAALRNPQWPLFLGRRSCPPASPVSLGVKDYANVEEALDKEPWIASPW 166

Query: 182 YSE------------ESVTGHHLKFTARDEPMITL--PRQFASREW 213
           Y +            ++V          D P+      R++A R  
Sbjct: 167 YRKKVHDSKRLQVVVDAVENGETTGQQSDMPLSFSQKHRRYAQRPV 212


>UniRef50_D1CGD4 CRISPR-associated protein Cas5 family n=6 Tax=Bacteria
           RepID=D1CGD4_THET1
          Length = 230

 Score =  211 bits (537), Expect = 2e-53,   Method: Composition-based stats.
 Identities = 68/226 (30%), Positives = 106/226 (46%), Gaps = 25/226 (11%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L++RL+GPMQ+WG  +    R TGR P++SG++GL+ A LG  R  T+ +  L   +
Sbjct: 1   MPTLLMRLSGPMQSWGTQSRFTVRDTGREPSKSGVIGLICAALGRPR--TAPVDDLV-RL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHET-----IQTWREYLCDASF 116
           +  VR D             +RDYHT  GA    R   +  T     +Q+ R YL DASF
Sbjct: 58  RMGVRVDR--------EGIVMRDYHTAGGAPAGERYGVATVTGDQRPVQSSRYYLADASF 109

Query: 117 TVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGT-------CQASDPQK 169
            VAL        ++ ++++A+  PR+  +LGR+SC  + P+ L          +  D + 
Sbjct: 110 LVALEGGEEDRPLLEQIDEALRAPRWQLFLGRKSCVPSEPIHLPKEPPLGPPIREEDLRT 169

Query: 170 ALLNYEPVGGDIYSEESVTGHHLKFTARDEPMIT--LPRQFASREW 213
           AL++Y    G             +    D P+      RQ+A+R  
Sbjct: 170 ALISYPWPEGAHRLRFVFEDPEGEELRNDVPISFEIGNRQYAARFV 215


>UniRef50_Q12YA8 CRISPR-associated protein, CT1976-like n=1 Tax=Methanococcoides
           burtonii DSM 6242 RepID=Q12YA8_METBU
          Length = 244

 Score =  209 bits (533), Expect = 5e-53,   Method: Composition-based stats.
 Identities = 63/244 (25%), Positives = 100/244 (40%), Gaps = 38/244 (15%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M+ YLI RL GPM +WG       RPT   P++S + GL+ A LGI+RD+      LS +
Sbjct: 1   MKEYLIFRLYGPMASWGDIAVGQHRPTYDHPSKSAIFGLIAAALGIRRDEEERHLELSNA 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVL-------------GAREDYRGLKSH--ETIQ 105
             +              +   LRDYHT                 R+D   +      T+ 
Sbjct: 61  YSYGTLI--------NSAGKLLRDYHTSQVPSAGTGRNRKTFATRKDELAVPKEELNTVL 112

Query: 106 TWREYLCDASFTVALWLTPH-ATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQA 164
           + R+Y CD  +TV L          +  L  ++ +P +  YLGR+SCPL  P+      A
Sbjct: 113 STRDYYCDGVYTVILSCKTDTPPYSLELLGNSLKEPSFCLYLGRKSCPLALPINPKIVSA 172

Query: 165 SDPQKALLNYEPVGGDIYSEESVTGHHL--------------KFTARDEPMITLPRQFAS 210
           S+ ++AL + +P    +  +  +   +                 +  D+ +     QF+ 
Sbjct: 173 SNIKEALQSVDPGEEGLVKKIEMKSPYRLYWDDPKESMTCEHTISRYDKLLSRKRWQFSK 232

Query: 211 REWY 214
           R  Y
Sbjct: 233 RNEY 236


>UniRef50_Q314I4 CRISPR-associated protein, CT1976 n=1 Tax=Desulfovibrio
           desulfuricans subsp. desulfuricans str. G20
           RepID=Q314I4_DESDG
          Length = 245

 Score =  209 bits (531), Expect = 7e-53,   Method: Composition-based stats.
 Identities = 79/246 (32%), Positives = 108/246 (43%), Gaps = 33/246 (13%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M  YL  ++ GP+QA+G       RPT   PTRS +LG+L A +GI+RD+ + L  L + 
Sbjct: 1   MAQYLTFQIYGPLQAYGTVAVGEIRPTSTMPTRSAVLGILAAAIGIRRDEETRLAELRDG 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGA----------REDYRGLKSHETIQTWREY 110
            + AVR D             + DYHT+             R D   L    TI + REY
Sbjct: 61  YRVAVRED--------APGKVMLDYHTIQTPGARGKRQLHCRRDELLLTEPNTILSRREY 112

Query: 111 LCDASFTVALWLTPHA-TMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQK 169
           L DA FTV LW   H     + E+ +A+  PR+T  LGR+SCP   P        + PQ+
Sbjct: 113 LMDALFTVCLWQANHTVPYSLQEIARALRSPRWTIGLGRKSCPPALPFAPKITDHTTPQE 172

Query: 170 ALLNYE-----------PVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREW---YV 215
           A+  Y            P    +  +        + T RD P+    RQFA R+     V
Sbjct: 173 AVAAYPADKLVSAGLRSPQVMRMLLDTEGPHTDTETTVRDVPLHHGRRQFAERKVRELLV 232

Query: 216 IKGGMD 221
            K   D
Sbjct: 233 RKAATD 238


>UniRef50_C2BET8 CRISPR-associated protein n=2 Tax=Firmicutes RepID=C2BET8_9FIRM
          Length = 244

 Score =  205 bits (522), Expect = 8e-52,   Method: Composition-based stats.
 Identities = 61/223 (27%), Positives = 101/223 (45%), Gaps = 29/223 (13%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
             ++L+L GPMQ+WG  +   TR +  +P++SG++G++ A  G +RD+   +Q L++ + 
Sbjct: 5   KTILLKLTGPMQSWGTSSRFETRTSDYYPSKSGVIGIIAASFGYERDEDEKIQKLND-LD 63

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWL 122
           FAVR D+             +DYH     R+     +   T  T R Y+ DA F VA+  
Sbjct: 64  FAVRVDQ--------EGVLKKDYHIA---RKVKPNGELERTYVTNRYYMEDAVFVVAI-- 110

Query: 123 TPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDIY 182
           +      + E+ + +  P + P++GRRSCPL     LGT +   P +AL N +    D +
Sbjct: 111 SHEDDKWMEEILQGLKYPYFQPFMGRRSCPLPARFILGTNE-EGPIEALENLDWQAADWF 169

Query: 183 SEE--------------SVTGHHLKFTARDEPMITLPRQFASR 211
            ++                   H     R        R+F  R
Sbjct: 170 KKKNKNYRADIYADKDLLPENSHTIRNDRVVSFSQKERKFGPR 212


>UniRef50_A3EQA4 CRISPR-ssociated protein, Cas5 n=3 Tax=Bacteria RepID=A3EQA4_9BACT
          Length = 227

 Score =  205 bits (522), Expect = 8e-52,   Method: Composition-based stats.
 Identities = 60/222 (27%), Positives = 94/222 (42%), Gaps = 22/222 (9%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L++RL  PMQ+WG  +    R TG+ P++SG++GLL A LGI R++   L+ L+  +
Sbjct: 1   MPTLLIRLVSPMQSWGTSSRFDQRDTGKEPSKSGVIGLLAAALGIDRNNWDDLEPLA-GL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
              VR D              RDY T           K H T  T+REYL DA F V   
Sbjct: 60  SMGVRHDR--------PGIPRRDYQTASKII-SADHSKIHPTAVTYREYLADAVFLVGFE 110

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                  ++ ++  A+  P +  +LGR+S   + P+++     + P +  L + P     
Sbjct: 111 SA--EVSLLEKINSALKNPVWPLFLGRKSYVPSEPIWIENGLKNVPLREALEHFPWIACR 168

Query: 182 YSEESVTGHH---------LKFTARDEPM-ITLPRQFASREW 213
              E +                   D+P+     R+F SR  
Sbjct: 169 RRNERLPEKLVITFESEDGTGVLKMDQPLSSFAKRRFGSRFV 210


>UniRef50_B0TDU1 Crispr-associated protein cas5 n=1 Tax=Heliobacterium modesticaldum
           Ice1 RepID=B0TDU1_HELMI
          Length = 230

 Score =  199 bits (507), Expect = 5e-50,   Method: Composition-based stats.
 Identities = 66/229 (28%), Positives = 101/229 (44%), Gaps = 23/229 (10%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
            L LRL GP+Q+WG  +    R +   PT+SG++GLLG  LG  R+D   L++L  +++ 
Sbjct: 5   ILALRLEGPLQSWGSRSRWDYRDSALEPTKSGIIGLLGCALGWSRNDK-RLESLDAALRL 63

Query: 64  AVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSH-----ETIQTWREYLCDASFTV 118
            VR D+          T L D+HTV G      G +        T+ + R YL +ASF  
Sbjct: 64  TVRIDK--------PGTPLIDFHTVQGYLLMAEGKQKKSGNDMYTVVSRRVYLQEASFLA 115

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQAS--DPQKALLNYEP 176
            L     A   + + +KA+  P +  +LGR+SCP   PLF    +    D  +A+ +   
Sbjct: 116 LLTGEQGA---LHQCKKALNDPVWPVFLGRKSCPPARPLFDSFYEGDFRDVLEAMRSIPW 172

Query: 177 ----VGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMD 221
                 G I     +     +   +D   I   R +  R   V    +D
Sbjct: 173 SSAPAAGPIRLRYVMEDEGGREWRQDVLRINGARMYGRRRVSVGWVDLD 221


>UniRef50_B8HWH8 CRISPR-associated protein Cas5 family n=1 Tax=Cyanothece sp. PCC
           7425 RepID=B8HWH8_CYAP4
          Length = 216

 Score =  199 bits (505), Expect = 8e-50,   Method: Composition-based stats.
 Identities = 52/218 (23%), Positives = 90/218 (41%), Gaps = 22/218 (10%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L+LR+  PM +WG  +    R + R PT+S ++GLL A LG  R    ++  L+ ++
Sbjct: 1   MPTLLLRMRAPMMSWGDHSRFTIRDSRREPTKSAVIGLLCAALGRPR--WEAVADLT-AL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +  VR ++  L           DYHTV  + +         T+ + R Y+ DA + V L 
Sbjct: 58  KMGVRINQEGLVQC--------DYHTVQDSIKSS--GSKGNTVISHRYYIADADYLVGLE 107

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
            +      +  L+ A+  P +  Y GR+S   + P+ L         +AL +   +   +
Sbjct: 108 GS--DRHFLESLDSALQSPIWQVYFGRKSFVPSCPVALHVSDQP-LAEALKHRITLSKTM 164

Query: 182 YSEE------SVTGHHLKFTARDEPMITLPRQFASREW 213
             +        +         +D P+    R F SR  
Sbjct: 165 AHKLPNRLRCVLEVPDSLDVRQDVPLDWQKRHFGSRCV 202


>UniRef50_Q04QB7 Putative uncharacterized protein n=2 Tax=Leptospira borgpetersenii
           serovar Hardjo-bovis RepID=Q04QB7_LEPBJ
          Length = 247

 Score =  198 bits (504), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 61/220 (27%), Positives = 93/220 (42%), Gaps = 18/220 (8%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M+ YL+ RL GP+ +WG       RP+  FPT+S ++GL+ A  G  R +   +  L +S
Sbjct: 1   MKDYLVFRLYGPLVSWGNIAVGEYRPSDSFPTKSAIIGLISASFGFDRSEDGKISELVKS 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSH----------ETIQTWREY 110
           V FA +               LRDYHT+       R L +           ETI + R+Y
Sbjct: 61  VFFATKTLN--------PGNLLRDYHTIQSPGNVKRSLLTRKDELLDSEYVETILSSRDY 112

Query: 111 LCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKA 170
             DA + VAL     A   + E+  A+L P +TPYLGR+SC +  P+      +     A
Sbjct: 113 RVDAVYDVALSEKKRAPYSLKEIRNALLSPIHTPYLGRKSCSIALPMCPEILSSDSFPNA 172

Query: 171 LLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFAS 210
              Y  +    Y            +++   ++ L      
Sbjct: 173 FEEYNKILMKKYESSDYKDPLADLSSKSSAILYLWEDPTE 212


>UniRef50_D0Y918 CRISPR-associated protein Cas5 family n=2 Tax=Dehalococcoides
           RepID=D0Y918_9CHLR
          Length = 205

 Score =  198 bits (504), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 64/213 (30%), Positives = 105/213 (49%), Gaps = 19/213 (8%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
            L++RL GPMQ+WG  +    R T   PTRSG++GL+ A +GI RD+     A  + ++ 
Sbjct: 6   TLLMRLEGPMQSWGYRSRFDCRDTALEPTRSGVIGLICAAMGIARDEDI---ARFDGIRM 62

Query: 64  AVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLT 123
            VR D     ++        DYHT L            +T+ ++R+YL DASFTV L  +
Sbjct: 63  GVRVDRDGKVEQ--------DYHTALDVI--KADGSGKDTVVSYRDYLTDASFTVGLESS 112

Query: 124 PHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDIYS 183
                ++ ++ KA++ P++  +LGR++ PLT P      + S+P K     E +     +
Sbjct: 113 --DRNLLEKIAKALVSPQWVLFLGRKAFPLTKPP---IFEFSNPVKPGSLEEHLLCGASA 167

Query: 184 EES-VTGHHLKFTARDEPMITLPRQFASREWYV 215
           +   +     + T  D P+    R+F  R + V
Sbjct: 168 KRVLLESPDGERTQYDWPLCFGERRFKPRRFTV 200


>UniRef50_Q0W584 Putative uncharacterized protein n=1 Tax=uncultured methanogenic
           archaeon RC-I RepID=Q0W584_UNCMA
          Length = 227

 Score =  197 bits (501), Expect = 3e-49,   Method: Composition-based stats.
 Identities = 61/213 (28%), Positives = 90/213 (42%), Gaps = 20/213 (9%)

Query: 10  AGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDE 69
            GPMQ+WG       R TG  PT+SG++GLLG  LG  R D      L   ++  +R + 
Sbjct: 12  EGPMQSWGLKARWDIRDTGDEPTKSGIIGLLGCALGYARKDPRLTDELDSQLRIGIRVE- 70

Query: 70  LILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPHATMV 129
                        RDYHTV G      G     TI ++R+YL DA+F V L        +
Sbjct: 71  -------CPGEIARDYHTVSGELRTAEGKLRETTIVSFRDYLQDAAFLVVLEGPGE---L 120

Query: 130 ISELEKAVLKPRYTPYLGRRSCPLTHPLFLG-TCQASDPQKALLNYEPVGGDIYSEES-- 186
           ++ +  A+  P +  YLGR+SCP T P+F   T   +    AL  +    G + + ++  
Sbjct: 121 LTRISNALKDPVWPIYLGRKSCPPTRPVFETLTTDYASIDDALSRHPWSSGTMEARKAHP 180

Query: 187 ------VTGHHLKFTARDEPMITLPRQFASREW 213
                 V      +   D    +  R +  R  
Sbjct: 181 KELKCIVEDLSGPYQRTDRMTKSPARMYGIRHV 213


>UniRef50_D0WFC8 CRISPR-associated protein Cas5 n=1 Tax=Slackia exigua ATCC 700122
           RepID=D0WFC8_9ACTN
          Length = 267

 Score =  197 bits (500), Expect = 3e-49,   Method: Composition-based stats.
 Identities = 62/246 (25%), Positives = 105/246 (42%), Gaps = 43/246 (17%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+L+LA P+Q+WG  +    R T   P++SG++GLL A LG +R+D  S+  L+ ++
Sbjct: 4   MTVLLLKLAAPLQSWGASSRFTERTTRHEPSKSGVIGLLAAALGRRRED--SVDDLA-AL 60

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLK---SHETIQTWREYLCDASFTV 118
           +FAVR D+          + +RD+ T    + D    +   +     + R+YL DA F  
Sbjct: 61  RFAVRIDQ--------PGSFMRDFQTEHTRKWDSDTRRFVFNESLSLSKRDYLSDAVFVA 112

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVG 178
           AL        +++E  +A+  P +  +LGRRSCP +  ++LG        +AL +     
Sbjct: 113 ALE---GDEDLLAECAEALHHPAFPLFLGRRSCPPSTQVYLGLVDGP-MMEALADIPWQA 168

Query: 179 GDI-----YSEESVTGHHLK------------------FTARDEPMITL--PRQFASREW 213
            +      Y                              T RD P+      R++  R  
Sbjct: 169 TERHWNYAYRFRGDKPKETVELKVVYEATEEQAACTLSETVRDVPLSFSQLKREYGWRTE 228

Query: 214 YVIKGG 219
             I+  
Sbjct: 229 TTIRMA 234


>UniRef50_B4S8P8 CRISPR-associated protein Cas5 family n=8 Tax=Bacteria
           RepID=B4S8P8_PROA2
          Length = 243

 Score =  195 bits (496), Expect = 8e-49,   Method: Composition-based stats.
 Identities = 55/241 (22%), Positives = 88/241 (36%), Gaps = 26/241 (10%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
           YL+L L  P+Q+WG  +  G R T  FPT+SG+LG+L   LG   +    L+ ++   Q 
Sbjct: 5   YLLLWLEAPLQSWGADSRFGRRGTLEFPTKSGVLGMLCCSLGAGGEQKELLEKMAPLKQS 64

Query: 64  AVRCDELILDDR-----RVSVTGLRDYHTVLGAREDYRGLK--------------SHETI 104
           A+         +           LRD+H V    +D    +              +  + 
Sbjct: 65  AISFCRTSKFRQEEIKKLDREPLLRDFHMVGSGYDDKNPWETLLIPKKSDGTTAVNGGSK 124

Query: 105 QTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQA 164
            T+R YL DA F V + +      +      A+  P +  Y GR+ C  T  ++ G    
Sbjct: 125 ITYRYYLQDAVFAVIMEVPSEKLTLF---ADALENPCWDIYFGRKCCAPTDFIYRGCFNT 181

Query: 165 SDP-QKALLNYEPVGGDIYSEESVTGHHLK--FTARDEPMITLPRQ-FASREWYVIKGGM 220
                   L        +     V G H        D P+    ++ +  R   VI    
Sbjct: 182 ESLAIGKALEIAQEKRLMEDFRVVDGEHEGEAIVLNDVPIQFGEQKLYRERRVTVISCAN 241

Query: 221 D 221
           +
Sbjct: 242 E 242


>UniRef50_A1ARH6 CRISPR-associated protein, Cas5e family n=2 Tax=Bacteria
           RepID=A1ARH6_PELPD
          Length = 232

 Score =  194 bits (492), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 59/228 (25%), Positives = 92/228 (40%), Gaps = 28/228 (12%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L+LRL GPMQ+WG  +    R TG+ P++SG++GLL A LGI R++   L+ L+  +
Sbjct: 1   MPTLLLRLVGPMQSWGTTSRFDQRDTGKEPSKSGVVGLLAAALGIDRENWVDLEPLT-CL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVL-----GAREDYRGLKSHETIQTWREYLCDASF 116
              VR D              RDY T          +          + + R YL DA+F
Sbjct: 60  AMGVRHDR--------PGVPKRDYQTAGCASTDTIIKADGTQAKGGGVVSQRFYLADAAF 111

Query: 117 TVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFL--GTCQASDPQKALLNY 174
            V L        ++  +  A+  P +T  LGR+S   +  +++  G   A    + L  Y
Sbjct: 112 LVGLEC--DDNCLLERIHVALHNPFWTLALGRKSYVPSESIWIVDGVRDAP-LLETLKRY 168

Query: 175 EPVGGDIYSEESVT--------GHHLKFTARDEPM-ITLPRQFASREW 213
             +      EE                    D+P+     R+F +R  
Sbjct: 169 PWIASSRSREEPPERLLVSIESDDGAGVLKMDQPLSSFAERRFGARFV 216


>UniRef50_C9M2Y8 CRISPR-associated protein n=1 Tax=Lactobacillus helveticus DSM
           20075 RepID=C9M2Y8_LACHE
          Length = 241

 Score =  193 bits (491), Expect = 4e-48,   Method: Composition-based stats.
 Identities = 51/200 (25%), Positives = 86/200 (43%), Gaps = 16/200 (8%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
                +RL  P+Q++G       R +  +P++S ++G++ A LG +RDD   LQ    ++
Sbjct: 1   MKTATIRLTAPLQSYGNQASFNQRTSDNYPSKSAVIGIIAAALGYRRDDARILQ--LNNL 58

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
            FAVR ++        S   + ++ TV    E  +         T+RE++ DA F VA+ 
Sbjct: 59  LFAVRIEQ--------SGNMMTEFQTV----EYQKSSTKTARKLTYREFIQDAVFMVAIG 106

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                   I ++  A+  P++  YLGRRS P   PL + T    +P + L          
Sbjct: 107 SDND--HEIEKIVSALKHPKFQLYLGRRSNPPAGPLMIETYDEENPLQVLEKLSWQAEPW 164

Query: 182 YSEESVTGHHLKFTARDEPM 201
           Y +       L     D  +
Sbjct: 165 YQKRLRAPKFLTRIIADAEL 184


>UniRef50_Q5YRB6 Putative uncharacterized protein n=1 Tax=Nocardia farcinica
           RepID=Q5YRB6_NOCFA
          Length = 235

 Score =  192 bits (487), Expect = 9e-48,   Method: Composition-based stats.
 Identities = 62/231 (26%), Positives = 98/231 (42%), Gaps = 36/231 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+LRLA P+Q+WG  +    R T ++P++SG+LGL+ A  G +R D   ++   +++
Sbjct: 1   MTVLLLRLAAPLQSWGVASRFARRETQQYPSKSGILGLIAAARGHRRTD--PIEEALQNL 58

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
            F VR D+            +RD+   L   +  +         + R YL DA F  A+ 
Sbjct: 59  AFGVRVDQ--------PGRLIRDFQVALNIDKTKQ------FPLSQRYYLADAVFLAAI- 103

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                  +I  +  A+ +P +  YLGRRSCP+T PL LG  +    + AL   E      
Sbjct: 104 --QGERGLIEGIGNALRRPEFPLYLGRRSCPVTGPLVLGEPRDVTLEHALHETEWQAATW 161

Query: 182 YSE---------------ESVTGHHLKFTARDEPMITLP--RQFASREWYV 215
           Y                        L+   RD P+   P  R++  R    
Sbjct: 162 YRRSQHRRVRLPIYRDLLPGDPVELLREQVRDMPLSFDPVRREYGWRTVVE 212


>UniRef50_D2RB02 CRISPR system CASCADE complex protein CasD n=3 Tax=Actinobacteria
           (class) RepID=D2RB02_GARVA
          Length = 291

 Score =  192 bits (487), Expect = 9e-48,   Method: Composition-based stats.
 Identities = 53/187 (28%), Positives = 86/187 (45%), Gaps = 17/187 (9%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQR--DDTSSLQALSE 59
              L+L+ +GP+Q+WG  +   TR T  +P++S ++G++ A  G +R  D   ++  L++
Sbjct: 1   MKSLLLKFSGPLQSWGTDSHFETRHTDYYPSKSAVIGMIAAAFGYRRSTDCDENIAKLND 60

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
            + FAVR D+            LRDYH               +   T R YL DA F VA
Sbjct: 61  -LDFAVRIDQ--------QGNLLRDYHIAAKY---KANGDFEKNYVTNRYYLEDAIFLVA 108

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGG 179
           +    +   +I ++  A+  P +   LGRRS P T    LG  +     +ALL +E +  
Sbjct: 109 I--GSNNEQLIYDISNALRSPYFQSSLGRRSLPPTADFILGV-EDCGVIQALLTHEWLAN 165

Query: 180 DIYSEES 186
               +  
Sbjct: 166 KWSKKRF 172


>UniRef50_A8SDR7 Putative uncharacterized protein n=1 Tax=Faecalibacterium
           prausnitzii M21/2 RepID=A8SDR7_9FIRM
          Length = 220

 Score =  191 bits (486), Expect = 1e-47,   Method: Composition-based stats.
 Identities = 74/221 (33%), Positives = 108/221 (48%), Gaps = 24/221 (10%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+LRLA P+QAWG  +   TR TGR PT+SG++GLL A LG++RD++ +L  L+  +
Sbjct: 1   MATLLLRLAAPLQAWGADSKFETRKTGREPTKSGVIGLLAAALGLRRDESEALTRLT-GL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +F VR +             L DYHT        +      +  T+R YL DA F   + 
Sbjct: 60  RFGVRVER--------EGQLLVDYHTA-------KTQDEKTSYVTYRHYLQDAVFLAGIE 104

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
            T   T ++ +L++A+L P +  YLGRR CP T PL LG C     Q+ L    P+    
Sbjct: 105 ST--DTALLQQLQQALLHPAFPLYLGRRCCPPTLPLCLGVCPG-SLQEVLQAEPPLCPGR 161

Query: 182 YSE---ESVTGHHLKFTARDEPMITLP--RQFASREWYVIK 217
            S    ++          RD P+   P  RQ+  R    + 
Sbjct: 162 QSRILLDADPLEPGTAPQRDVPVSFDPHHRQYGYRSVRELW 202


>UniRef50_B2GBJ9 Putative uncharacterized protein n=1 Tax=Lactobacillus fermentum
           IFO 3956 RepID=B2GBJ9_LACF3
          Length = 235

 Score =  191 bits (485), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 54/206 (26%), Positives = 81/206 (39%), Gaps = 23/206 (11%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQR--DDTSSLQALSE 59
              L++R+A P+Q++G P     R T R P++S ++G++GA LG +R  DD  SL  L  
Sbjct: 1   MKTLVIRIAAPLQSYGDPASFEKRTTFRAPSKSAVIGMIGAALGFRRESDDYKSLNDLD- 59

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
              FAVR D+            L D+                    + R YL DA F VA
Sbjct: 60  ---FAVRVDQ--------PGEVLSDFQITH-------YSLKKPGKLSHRIYLQDAVFMVA 101

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGG 179
           L     A  ++ E+E A+  P++  Y GRRS P    L +  C        L        
Sbjct: 102 LSSKQDA--LMEEIEYALRHPKFQLYFGRRSNPPAGILKMKMCPDKTAINVLKELPWQAS 159

Query: 180 DIYSEESVTGHHLKFTARDEPMITLP 205
             +  +            D  ++   
Sbjct: 160 VWFQRKYKKDVFNARIYADAKLVPDR 185


>UniRef50_A7BA63 Putative uncharacterized protein n=1 Tax=Actinomyces odontolyticus
           ATCC 17982 RepID=A7BA63_9ACTO
          Length = 242

 Score =  191 bits (485), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 68/245 (27%), Positives = 103/245 (42%), Gaps = 44/245 (17%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M + L+LRLAGPMQ+WG  +    R T  FPT+S L+GLLGA  G +R D   ++ L+E 
Sbjct: 1   MSAVLVLRLAGPMQSWGADSRFTRRSTEAFPTKSALVGLLGAAQGRRRSD--PIEDLAE- 57

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           +  AVR D+            L D+HT                  + R Y  DA+F   +
Sbjct: 58  LSVAVRVDQ--------PGQLLHDFHTAHRG--------DTSMPLSHRFYRADAAFGAFI 101

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180
                   +I  L +A+++P +  YLGRRSCP T PL L   + S    A+     +   
Sbjct: 102 EGPDD---MIDALAQAIVRPVFPLYLGRRSCPPTLPLRLAVREGSAW-DAVRETPWMAST 157

Query: 181 IYSEESVTGHHLKF-------------------TARDEPMITL--PRQFASREWYVIKGG 219
            Y ++    H ++                    T +D P+      R++  R        
Sbjct: 158 YYQKKQRHDHFVRMRVVADLGIIPPEVEKVAQQTLQDMPISFDSENRKYTLRTVEETYID 217

Query: 220 MDVSQ 224
           ++  Q
Sbjct: 218 LENPQ 222


>UniRef50_Q2JWC5 CRISPR-associated protein Cas5, Ecoli subtype n=1 Tax=Synechococcus
           sp. JA-3-3Ab RepID=Q2JWC5_SYNJA
          Length = 207

 Score =  190 bits (483), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 51/217 (23%), Positives = 90/217 (41%), Gaps = 31/217 (14%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L++RL  PM +WG  +    R + R PT+S ++G+L A LG  R     +  L+ ++
Sbjct: 1   MTTLLMRLRAPMMSWGDHSQFDYRDSRREPTKSAVIGILCAALGRPR--WEPVDDLA-AL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +  VR ++             +D+HTV             ET  + R Y+ D  + V L 
Sbjct: 58  KMGVRVNK--------EGILCKDFHTVQ----------IKET-ISNRYYVADGDYLVGLE 98

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                  ++  L++A+ KP +  +LGR+S   + PL +G  +     +AL  +       
Sbjct: 99  ---GDPNLLRTLDQALQKPYWQVFLGRKSFIPSRPLRVGLVEQP-LLEALRQHPYECSRR 154

Query: 182 YSEE-----SVTGHHLKFTARDEPMITLPRQFASREW 213
                     +         +D P+   PR+F  R  
Sbjct: 155 GKRPSQLRFVLEVSESLDVRQDVPLSWQPRRFGCRAV 191


>UniRef50_Q1EQS9 CRISPR-associated protein n=3 Tax=Streptomyces RepID=Q1EQS9_STRKN
          Length = 280

 Score =  190 bits (482), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 70/241 (29%), Positives = 107/241 (44%), Gaps = 39/241 (16%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           L+LRL+GP+Q+WG+ +    R T RFPTRSG++G+L A LG +R     +  L+  +   
Sbjct: 14  LLLRLSGPLQSWGERSHFNERDTARFPTRSGIIGMLAAALGRRRG--EPVDDLA-RLSLT 70

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKS---------HETIQTWREYLCDAS 115
           VR D             LRD HTV G       + +           T+ T R YL DA+
Sbjct: 71  VRTDR--------PGILLRDLHTVGGGLPAKATVTTAEGKKRPGTTGTLLTHRTYLADAA 122

Query: 116 FTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQAS------DPQK 169
           FT+AL  TP    ++ +  +A+  P +  +LGRRSCP   PL LG  + +       P  
Sbjct: 123 FTIALTSTPDDRPLLDQAAQALNTPCWPLFLGRRSCPPEGPLLLGASEDALHHLVHLPLA 182

Query: 170 ALLNYEPVGGDIYSEESV-------------TGHHLKFTARDEPMITLPRQFASREWYVI 216
           A         +  ++  +              G H      D+P+   PR+ + R   + 
Sbjct: 183 AHPGRGQQDTEFLADRPLNRLPYGTATPVGADGTHPSGEVNDQPLSFDPRRRSYRARPLY 242

Query: 217 K 217
           +
Sbjct: 243 R 243


>UniRef50_A5GBK2 CRISPR-associated protein Cas5 family n=2 Tax=Deltaproteobacteria
           RepID=A5GBK2_GEOUR
          Length = 231

 Score =  189 bits (481), Expect = 5e-47,   Method: Composition-based stats.
 Identities = 61/225 (27%), Positives = 98/225 (43%), Gaps = 10/225 (4%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE-- 59
           +S+L LRL GP+Q+WG  +    R TG  PT+S + G+  A LG  R      + L    
Sbjct: 10  KSFLALRLEGPLQSWGFDSQYNRRNTGLMPTKSAIAGMCCAALGFLRGCDKEQEFLVAFG 69

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
           +V+            + + V  L+DYHTV   R    G  +++ + T R+YL DA+F V 
Sbjct: 70  AVRMTAIAIPRNGAKKELPVRRLQDYHTVQNTRR-ASGAINNDCVLTHRQYLTDAAFGVL 128

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGG 179
           L      + ++ ++  A+  P +  +LGR++C  T P+  G  +  D    LL  +    
Sbjct: 129 LE---GDSTLLKQIAAALENPVWGVWLGRKTCIPTAPVLAGLRENRDEALKLLLKDKPLE 185

Query: 180 DIYSEESVT---GHHLKFTARDEPMITLPRQFASREWYVIKGGMD 221
               +E V                  T  R F+ R    ++ G D
Sbjct: 186 SFARQEDVESFADGRDSLPDMPVSFATERRIFSPRRVRTLQ-GTD 229


>UniRef50_UPI0001AF1D4C CRISPR-associated protein, CT1976 n=1 Tax=Streptomyces ghanaensis
           ATCC 14672 RepID=UPI0001AF1D4C
          Length = 244

 Score =  189 bits (480), Expect = 7e-47,   Method: Composition-based stats.
 Identities = 59/240 (24%), Positives = 89/240 (37%), Gaps = 41/240 (17%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L++    PMQ+WG  +   +R T   PT+SG++GLL A LGI RD    +Q L+E +
Sbjct: 1   MATLLMCFDAPMQSWGTRSQFASRDTATEPTKSGVVGLLAAALGIPRDADEEIQNLAE-L 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +  VR D   + +         D+HTV          K+H T  T R YL DA F V + 
Sbjct: 60  RMGVRVDREGVVEA--------DFHTVQNVPNTE--GKNHRTAVTKRFYLADALFLVGVE 109

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPL-FLGT------CQASDPQKALLNY 174
                T ++ +L  A+  PR+  Y GR++     P+   G               AL  +
Sbjct: 110 --SDDTQLLHQLHTALTAPRWPLYFGRKAFVPARPIPSPGLAGEHHPVTGQSLDDALRTH 167

Query: 175 EPVGGD-----------------IYSEESVTGHHL--KFTARDEPMITLP--RQFASREW 213
             +                                       D P+      R +A R  
Sbjct: 168 PWLENQLRIHANRRTTAYAPSPAWLRTIVDADPLALDVELRHDHPLSFTQQDRSYAPRAV 227


>UniRef50_C7MQD6 CRISPR-associated protein Cas5 n=1 Tax=Saccharomonospora viridis
           DSM 43017 RepID=C7MQD6_SACVD
          Length = 236

 Score =  189 bits (479), Expect = 8e-47,   Method: Composition-based stats.
 Identities = 71/219 (32%), Positives = 104/219 (47%), Gaps = 20/219 (9%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+L L GPMQAWG  +    R T  +PTRSG++G++ A LG Q  D  SL  LS  +
Sbjct: 1   MTTLVLHLDGPMQAWGHASQWDHRDTLDYPTRSGVIGMIAAALGKQWGD--SLDDLSP-L 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGARE----DYRGLKSHETIQTWREYLCDASFT 117
           +F +R D             + DYHT  G  E      +G      + + R Y+ DA++T
Sbjct: 58  RFTIRIDR--------PGRRIVDYHTAGGGYEVGIARVKGGNRAHAVLSDRFYMSDAAYT 109

Query: 118 VALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQK-ALLNYEP 176
           VA+        ++  ++ A+  P + P+LGRRSCP   P  LG       +   L   +P
Sbjct: 110 VAIT---GPDTLLYRVDDALRAPVFGPFLGRRSCPPAGPWHLGLHDGDPLRTLPLHRDKP 166

Query: 177 VGGDIYSEESVTGHHLKF-TARDEPMITLPRQFASREWY 214
             GD  + E V+ H     T R +  +T P +F  R  Y
Sbjct: 167 RDGDTVAVEFVSDHETHGPTDRVDTTLTDPHEFGPRRSY 205


>UniRef50_A5UR14 CRISPR-associated protein, Cas5e family n=1 Tax=Roseiflexus sp.
           RS-1 RepID=A5UR14_ROSS1
          Length = 262

 Score =  188 bits (478), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 75/259 (28%), Positives = 102/259 (39%), Gaps = 55/259 (21%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L LRL GP+Q+WG     G R T   PT+SG++GLLG  LG++RDD + L+ LS+++
Sbjct: 1   MNTLFLRLEGPLQSWGLRARWGERDTTDAPTKSGVIGLLGCALGLRRDD-ARLRDLSDNL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKS--------------------- 100
           +  VR D        +    +RDYHT  G R                             
Sbjct: 60  RMGVRVD--------LPGILMRDYHTTGGGRYSTIASTGGPRYHDEPYIGGVLSAEVTKG 111

Query: 101 ------------HETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGR 148
                        ET  + R YL DASF VAL  +P     I EL  A+  P +  +LGR
Sbjct: 112 RIKVKINQKTGEPETDVSERYYLADASFLVALQGSPD---YIGELATAIQSPVWPLFLGR 168

Query: 149 RSCPLTHPLFLGTCQASDPQKALLNY---EPVGGDIYSEESVTGHHLKFT-------ARD 198
           ++C  + P+F GT Q    + AL N      V              L  T         D
Sbjct: 169 KACVPSTPIFAGTGQFDILEDALKNLLLSPRVETAWQRSRPTQLRLLIETGPGAGNRQYD 228

Query: 199 EPMITLPRQFASREWYVIK 217
                  R F +R      
Sbjct: 229 NIGTPSRRVFRARYVRETW 247


>UniRef50_B1VIY0 CRISPR-associated protein n=9 Tax=Actinomycetales
           RepID=B1VIY0_CORU7
          Length = 240

 Score =  186 bits (473), Expect = 4e-46,   Method: Composition-based stats.
 Identities = 61/234 (26%), Positives = 100/234 (42%), Gaps = 33/234 (14%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M   L+L L GPMQ+WG  +    R T   PT+SG++GL+ A  G +R D   ++ L++ 
Sbjct: 1   MAHSLLLLLKGPMQSWGDESRFSVRATATTPTKSGIVGLIAAAQGRRRTD--GVEDLAK- 57

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           ++ AVR D+        S + LRDY T       +            R +L DA+F  A+
Sbjct: 58  LRMAVRVDQ--------SGSLLRDYQTAQ----PWLKNPGANASLVTRYFLSDAAFVAAV 105

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180
                   ++ ++ +A+ +P Y  Y+GRRSCP+   L +G     D + AL  ++     
Sbjct: 106 E--SEDRELLDQMAEALRRPAYPLYMGRRSCPVHPGLVIGVVDG-DAESALRAHDTWHAT 162

Query: 181 IYSEESV-------------TGHHLKFTARDEPMITLP--RQFASREWYVIKGG 219
               +                G       +D P+   P  R++  RE    +  
Sbjct: 163 AVHRKESPKKVSLAIYRDANPGEGGSVPRQDVPVSFSPEHRKYGWREVIRAEDV 216


>UniRef50_B0S4B6 Putative uncharacterized protein n=1 Tax=Finegoldia magna ATCC
           29328 RepID=B0S4B6_FINM2
          Length = 228

 Score =  185 bits (471), Expect = 7e-46,   Method: Composition-based stats.
 Identities = 60/239 (25%), Positives = 107/239 (44%), Gaps = 33/239 (13%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            S ++L+ A P+Q+WG       R T  +PT+S ++GL+ A  G ++ DT S++ L+ S+
Sbjct: 1   MSVILLKFASPLQSWGGLANYEIRNTEYYPTKSAVIGLVAAAFGYKKTDTESIKRLN-SL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTW---REYLCDASFTV 118
            F+VR D+          + +RD+   +     Y     +  +++    + Y+ DA F +
Sbjct: 60  NFSVRIDQ--------KGSLIRDFQIAMEYNPKYMPNDPNYFVKSNLIQKYYIQDAKFLI 111

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVG 178
           AL  +     ++ ++  A+  P Y  +LGR+S P+     +G    ++  + + +YE + 
Sbjct: 112 AL--SSDDETLMEDVYNALESPAYQLFLGRKSNPINADYLIGKFDGNEL-EIIKDYEWLA 168

Query: 179 GDIYSE--------------ESVTGHHLKFTARD--EPMITLPRQFASR--EWYVIKGG 219
              Y +                 TG   K   RD  E      R F+SR    YV K G
Sbjct: 169 SKWYKKSIKKDSVELSIFSDYIDTGSKEKLIRRDLTESFENTKRDFSSRFEYRYVTKVG 227


>UniRef50_Q1R114 CRISPR-associated protein, CT1976 n=1 Tax=Chromohalobacter
           salexigens DSM 3043 RepID=Q1R114_CHRSD
          Length = 260

 Score =  185 bits (470), Expect = 8e-46,   Method: Composition-based stats.
 Identities = 66/184 (35%), Positives = 92/184 (50%), Gaps = 20/184 (10%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M  +L+ RL  PM +WG+      RPT  +P R  +LGL+GA LGI+RDD      L +S
Sbjct: 1   MTGHLVFRLYAPMASWGEAAVGEARPTATYPGRGAILGLIGAALGIRRDDDEGQLRLRQS 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYR------------GLKSHETIQTWR 108
           +  AV+        +R     LRDYHTV       +               +  TI + R
Sbjct: 61  LGIAVK--------QRSPGWLLRDYHTVQVPPSQSKVNYRSRREELSVPKDALNTILSSR 112

Query: 109 EYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQ 168
           +Y CD  + VAL L P A   + EL+ A+ +PR+T YLGR++CPL  PL     +A   +
Sbjct: 113 DYRCDGLWVVALRLMPDAVWTLDELKSALERPRFTLYLGRKACPLAAPLTPAIVEADHWR 172

Query: 169 KALL 172
            AL 
Sbjct: 173 GALD 176


>UniRef50_A6W168 CRISPR-associated protein Cas5 family n=6 Tax=Gammaproteobacteria
           RepID=A6W168_MARMS
          Length = 258

 Score =  185 bits (470), Expect = 1e-45,   Method: Composition-based stats.
 Identities = 78/253 (30%), Positives = 109/253 (43%), Gaps = 43/253 (16%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M+ YL+ RL GPM +WGQP   G R T   PTRS +LGLLGA LGI+RDD   L AL  S
Sbjct: 1   MKDYLVFRLYGPMASWGQPAVGGDRATAIAPTRSAILGLLGAALGIKRDDAQQLDALHSS 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRG-------------LKSHETIQTW 107
           VQ A +        +    + LRDYHT      + +               +   TI + 
Sbjct: 61  VQMATK--------QVTPTSLLRDYHTSQVPSRNNKYVYRTRKNELLDEHKEKLNTILST 112

Query: 108 REYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDP 167
           R+Y CD  + VA+ LT  +   +  L++A++KP Y   LGR+SCPL  PL      +   
Sbjct: 113 RDYRCDGIWIVAVSLTQESLFSLERLKQALIKPVYVLSLGRKSCPLAAPLLPVLLTSVSL 172

Query: 168 QKALL---------NYEPVGGDIYS-------------EESVTGHHLKFTARDEPMITLP 205
           ++AL          +   +                   +E      L     D+P+    
Sbjct: 173 REALDYPFPSIIDNDKPHLDAVWLRPNKLSTYTWEGSVDEFSGETALTTHPWDDPINRDR 232

Query: 206 RQFASREWYVIKG 218
            QF  R  + I  
Sbjct: 233 WQFKQRTMHQITV 245


>UniRef50_Q47PI7 CRISPR-associated protein, Cas5e family n=12 Tax=Actinomycetales
           RepID=Q47PI7_THEFY
          Length = 245

 Score =  184 bits (467), Expect = 2e-45,   Method: Composition-based stats.
 Identities = 69/233 (29%), Positives = 99/233 (42%), Gaps = 36/233 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L L LAGP+QAWG  +    R T   PT+SG+LGLL A  G +R D   L  L+ ++
Sbjct: 1   MKVLTLLLAGPLQAWGAASRFTRRTTEHAPTKSGVLGLLAAAQGRERTDD--LSDLA-AL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +F VR D+          T +RD+ T +                + R YL DA F  A+ 
Sbjct: 58  RFGVRVDQ--------RGTRIRDFQTAIHLD------TGKSMPVSERFYLADAVFVAAVE 103

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                  +I  L +AV  P Y PYLGRRSCP + P+ LG       ++ L   +    + 
Sbjct: 104 ---GEDTLIDTLHQAVQHPVYLPYLGRRSCPPSRPINLGVHSGKPLEQVLAEEKWHAANW 160

Query: 182 YSE--------------ESVTGHHLKFTARDEPMITLP--RQFASREWYVIKG 218
           Y                ++  G     + RD P+   P  R++A R    +  
Sbjct: 161 YQRQLRDLPEVPLDLLVDAPPGDPGADSLRDLPISFDPVHRRYALRGVRTLTV 213


>UniRef50_A8M404 CRISPR-associated protein Cas5 family n=1 Tax=Salinispora arenicola
           CNS-205 RepID=A8M404_SALAI
          Length = 238

 Score =  184 bits (466), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 65/229 (28%), Positives = 96/229 (41%), Gaps = 35/229 (15%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           L+LRLAGP+Q+WG  +    R T   PT+SG++G+L A  G++R D   L  L  S+ F 
Sbjct: 2   LLLRLAGPLQSWGATSRFTHRHTQVTPTKSGVIGMLAAASGLRRTD--PLTELL-SLDFG 58

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTP 124
           VR D+            LRD+                    T R YL DA F VA+    
Sbjct: 59  VRIDQ--------PGQLLRDFQVARTLDG------RDSMPLTNRYYLSDAVFLVAI---G 101

Query: 125 HATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDIYSE 184
               ++  L ++V +P +  YLGRR+CP   P+ LG        +AL ++         E
Sbjct: 102 GDQALLEGLHESVRRPHFPLYLGRRACPPVAPISLGVHPG-TVDEALRDWPWQAAKRLRE 160

Query: 185 E------------SVTGHHLKFTARDEPMITLP--RQFASREWYVIKGG 219
                        +  G  +  T  D+P+   P  RQ+  R     +  
Sbjct: 161 RGELTVPLEVVSDAPPGADVTETLPDQPISFDPAHRQYGWRAVVRTRIV 209


>UniRef50_D1A6Q5 CRISPR-associated protein Cas5 family n=2 Tax=Actinomycetales
           RepID=D1A6Q5_THECD
          Length = 273

 Score =  183 bits (465), Expect = 4e-45,   Method: Composition-based stats.
 Identities = 70/243 (28%), Positives = 102/243 (41%), Gaps = 44/243 (18%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+L L+GP+Q+WG+ +    R T   PTRSGL+G++ A  G +R  T  +  L  ++
Sbjct: 6   TTGLLLHLSGPLQSWGERSRFNQRDTATAPTRSGLIGMIAAAFGRRR--TEPVTDL-RAL 62

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLG---------AREDYRGLKSHETIQTWREYLC 112
           +F VR D           T LRD+HTV G           E  R      T+ + R YL 
Sbjct: 63  RFTVRIDR--------PGTLLRDFHTVGGGMPRDLTVITAEGKRRAADTATVTSDRYYLQ 114

Query: 113 DASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALL 172
           DA+FTVA+        ++    +A+  PR+  YLGRRSCP   PL L T   +DP  AL+
Sbjct: 115 DAAFTVAVTA--DDPALLDRCAQALRAPRWPLYLGRRSCPPNAPLLL-TVLRTDPVTALI 171

Query: 173 NYEP---------------------VGGDIYSEESVTGHHLKFTARDEPMITLPRQFASR 211
           +                              S       + +            R+F +R
Sbjct: 172 DLPLARTAPRDRGDVLVEFRSDTPFESRAWPSAPEDEQVYTEAQDEPVSFQPHHRRFQTR 231

Query: 212 EWY 214
             Y
Sbjct: 232 PIY 234


>UniRef50_C5SD48 CRISPR-associated protein Cas5 family n=1 Tax=Allochromatium
           vinosum DSM 180 RepID=C5SD48_CHRVI
          Length = 227

 Score =  182 bits (463), Expect = 6e-45,   Method: Composition-based stats.
 Identities = 108/225 (48%), Positives = 134/225 (59%), Gaps = 9/225 (4%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M SYLILRL GPMQAWG  TFE  RP+  FPTRSGLLGLLGACLG+ R DT SL AL+ES
Sbjct: 1   MPSYLILRLDGPMQAWGTHTFEDYRPSNPFPTRSGLLGLLGACLGLDRSDTPSLDALAES 60

Query: 61  VQFAVRCDELILDD-----RRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDAS 115
           V F VR D                T L DYHTVL AR+   G  +   IQ+ REYL DA+
Sbjct: 61  VAFTVRLDTGAPRPGVDRLMPKRHTKLSDYHTVLDARKV-DGSTNKFPIQSHREYLFDAA 119

Query: 116 FTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPL--FLGTCQASDPQKALLN 173
           F VA+   P A+  ++ + +++ +PR+TP LGRRSCPL  PL       +A D + AL  
Sbjct: 120 FAVAIGSRPDASFSLARIAESLRQPRFTPVLGRRSCPLGRPLLERPDCIEADDAKAALAQ 179

Query: 174 YEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKG 218
           + P GG IYSE+ +      +  RD P     RQFA+R  Y+ + 
Sbjct: 180 FPPHGGLIYSEDELVSDQPTWI-RDVPRYGRHRQFATRRLYLHRE 223


>UniRef50_C7LYW6 CRISPR-associated protein Cas5 family n=1 Tax=Acidimicrobium
           ferrooxidans DSM 10331 RepID=C7LYW6_ACIFD
          Length = 253

 Score =  182 bits (463), Expect = 6e-45,   Method: Composition-based stats.
 Identities = 74/238 (31%), Positives = 95/238 (39%), Gaps = 41/238 (17%)

Query: 2   RSYLILRLAGPMQAWGQPTF-EGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
            S L LRL GP+QAWG     +  R T RFPT+SG++GLL A LG  R   ++L  L  +
Sbjct: 1   MSVLALRLGGPLQAWGSSQRLDHYRRTERFPTKSGVIGLLAAALGRPRS--AALDDLG-A 57

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHE----------------TI 104
           ++FAVR D             LRD+HT+    +D +     E                T 
Sbjct: 58  LRFAVRIDR--------PGEVLRDFHTLSSLFDDKKRFAPGEGRLPTASGGYRSAATSTQ 109

Query: 105 QTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQA 164
            T R YL DA F   L         + EL+ A+  P +  YLGRRSCP   PL LG    
Sbjct: 110 VTERFYLADACFVAGLE---GDAAQLQELDDALRTPVFPLYLGRRSCPPDKPLRLGVYDG 166

Query: 165 SDPQKALLNYEPVGGD-------IYSEESVTGHHLKFTARDEPMITLP--RQFASREW 213
                 L +      D       I  E  V          D+     P  R +  R  
Sbjct: 167 -GLIDVLASIPWQANDPAQSATSIRCELVVENPAGDVELADQARSFDPLTRSYTRRRV 223


>UniRef50_A1SV73 CRISPR-associated protein, Cas5e family n=2 Tax=Gammaproteobacteria
           RepID=A1SV73_PSYIN
          Length = 217

 Score =  182 bits (463), Expect = 6e-45,   Method: Composition-based stats.
 Identities = 78/214 (36%), Positives = 110/214 (51%), Gaps = 15/214 (7%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              LIL+  G M A+G  TF+  R    FPTRS ++G+LGA +GI R++ + L ALSE +
Sbjct: 1   MKTLILKTEG-MSAYGLQTFDVHRRANHFPTRSAIMGILGAAMGITRENFNELYALSEQL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           + AV+          +S   + DYHTV   R   +G        T+REY CD+  T A+ 
Sbjct: 60  KIAVQV--------NLSGEKMVDYHTVQHFRSP-QGKIQKGVKPTYREYWCDSEHTFAIS 110

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
               A  VI +L  +V  P +T + GR+SCPLT PLF       +P  AL N+    G I
Sbjct: 111 A---AEHVIEKLVNSVKFPEFTLFQGRKSCPLTRPLFEAVTDDDNPANALKNHGEQ-GQI 166

Query: 182 YSEESVTGHHLKFTARDEPMITLPRQFASREWYV 215
           +S+ S          RD  +  +PR++A R  YV
Sbjct: 167 FSDISGDNQLAIVQVRDL-ITAIPRKYAMRTVYV 199


>UniRef50_Q03C60 CRISPR-associated protein n=4 Tax=Lactobacillus RepID=Q03C60_LACC3
          Length = 236

 Score =  180 bits (457), Expect = 3e-44,   Method: Composition-based stats.
 Identities = 59/234 (25%), Positives = 90/234 (38%), Gaps = 37/234 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              + +RL  P+Q++G       R TG +P++S ++G+L A LG QRDD  ++ AL++ +
Sbjct: 1   MKTISIRLTSPLQSYGNEAQFARRTTGDYPSKSAIIGMLAAALGYQRDD-PAINALNDLL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
            FAVR D+            + ++ T           K      T+R+ L DA F VA+ 
Sbjct: 60  -FAVRVDQ--------PGQVMTEFQTAE--------WKPGTRKLTYRDLLQDAVFVVAI- 101

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                   +  L +A+  PR+  YLGRR+      L + T    DP   L          
Sbjct: 102 -GSEDEAWLDRLAEALRHPRFQLYLGRRANVPAGVLKIQTFAGQDPVGVLAQLPWQASRW 160

Query: 182 YSEESVT---------------GHHLKFTARDE--PMITLPRQFASREWYVIKG 218
           Y   S                         RD         RQ++ R   V K 
Sbjct: 161 YQRRSRRQASMSVQLIADAVLLPERRADLVRDAVHSFDQKHRQYSFRPIAVTKV 214


>UniRef50_C8XAY4 CRISPR-associated protein Cas5 family n=2 Tax=Actinomycetales
           RepID=C8XAY4_NAKMY
          Length = 252

 Score =  180 bits (456), Expect = 3e-44,   Method: Composition-based stats.
 Identities = 67/210 (31%), Positives = 92/210 (43%), Gaps = 20/210 (9%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            S L+LRL GPMQ+WG+ +    R T   P++S ++GLL A LG +R D  +++ L+  +
Sbjct: 1   MSVLVLRLTGPMQSWGERSRYARRETAAEPSKSAIVGLLAAALGRRRTD--AIEDLA-GL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
            F VR D+          T LRD+ T                  + R YL DA F  A+ 
Sbjct: 58  IFGVRVDQ--------PGTLLRDFQTARSLDGAR------TMPLSERYYLSDARFLAAVE 103

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                  +I+ L  A+  P +  YLGRRSCP + P+    C  S P  A L  EP     
Sbjct: 104 ---GPESLIAGLAGALRDPTFPLYLGRRSCPPSEPIAQQDCIRSGPLLAALFDEPWHATK 160

Query: 182 YSEESVTGHHLKFTARDEPMITLPRQFASR 211
                V        A D     +P Q A R
Sbjct: 161 SYRRRVADPARLSIAVDAAATEVPAQLAER 190


>UniRef50_A8LYZ7 CRISPR-associated protein Cas5 family n=2 Tax=Actinomycetales
           RepID=A8LYZ7_SALAI
          Length = 257

 Score =  180 bits (456), Expect = 4e-44,   Method: Composition-based stats.
 Identities = 77/243 (31%), Positives = 107/243 (44%), Gaps = 43/243 (17%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+LRLAGPMQ+WG  +    R TG  PTRS ++G++ A  G  R     L  L+  V
Sbjct: 1   MTGLLLRLAGPMQSWGDHSTFSVRDTGTVPTRSAMIGIIAAAQGRHRG--EPLGDLAP-V 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLK---------SHETIQTWREYLC 112
           QF VR D           T + D+HTV G     R +             TI + R YL 
Sbjct: 58  QFTVRVDR--------PGTVMSDFHTVGGGAPPERTVPTAEGKRRTAGAGTIVSRRFYLA 109

Query: 113 DASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKAL- 171
           DA FTVA+        ++ ++  A+  P + PYLGRRSCP+ HP  L +    DP   L 
Sbjct: 110 DAVFTVAVTGPDD---LVGQIHTALNNPVWGPYLGRRSCPVAHPF-LMSGPIPDPVGRLE 165

Query: 172 -----LNYEPVGGDIYSEESV------TGHHLKFTARDEPMITLP-------RQFASREW 213
                    P   +    + V       G   + T  D PM  +P       R++ +R+ 
Sbjct: 166 HLPLNRRRPPGDEETVRVDFVTGAPHGDGSISRMTLNDVPMEPVPGSPDPRRRRYLTRQV 225

Query: 214 YVI 216
           YV 
Sbjct: 226 YVT 228


>UniRef50_Q2RY19 CRISPR-associated protein, Cas5e family n=1 Tax=Rhodospirillum
           rubrum ATCC 11170 RepID=Q2RY19_RHORT
          Length = 261

 Score =  179 bits (454), Expect = 7e-44,   Method: Composition-based stats.
 Identities = 70/216 (32%), Positives = 95/216 (43%), Gaps = 21/216 (9%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
           R +L+ RL GPM AWG       R T   P +S +LGLL A LGI R D ++ +AL   +
Sbjct: 4   RDFLVFRLVGPMAAWGDIAVGERRGTWDVPAKSAILGLLAAGLGIDRADRTAHEALDRGL 63

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVL----------GAREDYRGLKSHETIQTWREYL 111
            FAVR D             LRDYHT              R D        T+ + R Y 
Sbjct: 64  GFAVRQDR--------PGRLLRDYHTAQAPKARKNARWSTRRDELNDDDLNTVLSDRLYR 115

Query: 112 CDASFTVALWLTPH-ATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKA 170
            +A  T A+W         + +L +A+L+PR+TPYLGR++CPL  P      QA     A
Sbjct: 116 TNAIATPAIWRRQGTEGPTLDQLTQALLRPRFTPYLGRKACPLGWPPRPRLLQADGLLAA 175

Query: 171 LLNYEPVGGDIYSE--ESVTGHHLKFTARDEPMITL 204
              Y+    D   +  ++  G     T R  P+   
Sbjct: 176 FDAYDSAEWDAARQFHKAYPGGWPGDTDRPTPVWFE 211


>UniRef50_C7MTB0 CRISPR-associated protein Cas5 n=1 Tax=Saccharomonospora viridis
           DSM 43017 RepID=C7MTB0_SACVD
          Length = 255

 Score =  178 bits (452), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 73/234 (31%), Positives = 104/234 (44%), Gaps = 36/234 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            S L+LRLAGP+Q+WG+ +    R T  FPT SGLLGLL   +G +R    SL+ L+ ++
Sbjct: 1   MSGLLLRLAGPLQSWGERSTFDVRDTAGFPTHSGLLGLLACVMGRRRG--ESLEDLA-AL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLK---------SHETIQTWREYLC 112
            F +R D           T + DY T  GA      +             T+QTWREYL 
Sbjct: 58  TFTIRVDR--------PGTRIIDYQTAGGALPPSMKVPTADGKGRPAGKGTVQTWREYLA 109

Query: 113 DASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALL 172
           DA F VA+      + V+ ++  A+  P + PYLGRRSCP   PL L      DP   L 
Sbjct: 110 DAVFVVAV---QGPSEVLDQVRHALRYPHWQPYLGRRSCPPDQPLLLDV-PVEDPVAELC 165

Query: 173 NYEPVGGDIYSE------------ESVTGHHLKFTARDEPMITLPRQFASREWY 214
              P+   +  +            E   G   +         ++ R ++ R  +
Sbjct: 166 TRVPLARRVGKDEETVPVDFIFPVERRDGVRSEIHDVPVAFTSVDRAYSPRPVW 219


>UniRef50_D2L2X8 CRISPR-associated protein Cas5 family n=1 Tax=Desulfovibrio sp.
           FW1012B RepID=D2L2X8_9DELT
          Length = 266

 Score =  178 bits (452), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 70/249 (28%), Positives = 98/249 (39%), Gaps = 45/249 (18%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M  YLI +L G + A+G       R +   PTRS + GLL ACLGI+R + + L ALS  
Sbjct: 1   MARYLIFQLYGMLAAYGLVAVGEVRLSAGHPTRSAVFGLLAACLGIRRHEEARLAALSGG 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL---------------KSHETIQ 105
              AVR D           T L DYHT+    E  + +               +   T+ 
Sbjct: 61  YALAVRVD--------APGTSLLDYHTIQTPPEKSKRIYRTRADELGGLLGIDEPPYTVL 112

Query: 106 TWREYLCDASFTVALW------LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFL 159
           + R YLCDA FT  L               +  L +A+ +P  TPYLGR+SCP + P   
Sbjct: 113 SRRGYLCDAHFTACLTPAAAPPTDATPPHTLEALAEALRRPVLTPYLGRKSCPPSLPFHP 172

Query: 160 GTCQASDPQKALLNY------------EPVGGDIYSEESVTGHHLKFT----ARDEPMIT 203
              +    + AL +Y                  ++++E         T     RD  +  
Sbjct: 173 RLGEYDSLEAALADYPLEKLAFPAGLKPHDPAVVFADEDEAITPATVTSRPLVRDRTVQH 232

Query: 204 LPRQFASRE 212
             R F  R 
Sbjct: 233 GRRLFEERR 241


>UniRef50_A8ZZ17 CRISPR-associated protein Cas5 family n=1 Tax=Desulfococcus
           oleovorans Hxd3 RepID=A8ZZ17_DESOH
          Length = 259

 Score =  178 bits (452), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 67/259 (25%), Positives = 99/259 (38%), Gaps = 54/259 (20%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             YL+ RL GPM +WG+     TR T  +P RS ++GL+ A LGI+R +T + QAL +  
Sbjct: 1   MGYLLFRLYGPMASWGEIAVGETRHTANYPGRSAIIGLMAAALGIKRSETENQQALDQGC 60

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVL----------GAREDYR--GLKSHETIQTWRE 109
             AV        + R   + LRDYHT              R D    G     TI + RE
Sbjct: 61  LIAV--------EARSHGSLLRDYHTTQVPDSVGGFVYRTRRDELIIGKPRLGTILSSRE 112

Query: 110 YLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGT-CQASDPQ 168
           Y  DA    A+ + P A   +  ++  + +PR   YLGR+SCPL+ P+       + +  
Sbjct: 113 YRQDALAVSAVRVLPGARYELQTIKTHLEQPRLHVYLGRKSCPLSAPMNPQIDKTSRNFH 172

Query: 169 KALLNYEPVGGDIYSEESVTG---------------------------------HHLKFT 195
           +A   Y              G                                       
Sbjct: 173 EAFQAYAHQPLLPVHHSGKEGLSKRDAYWLGLANDRHYYWEGEPSEFSDTIDLSRVQTRI 232

Query: 196 ARDEPMITLPRQFASREWY 214
             D+P+     QF+ R+ +
Sbjct: 233 RHDQPLSRTRWQFSPRQEH 251


>UniRef50_D1CAJ0 CRISPR-associated protein Cas5 family n=1 Tax=Sphaerobacter
           thermophilus DSM 20745 RepID=D1CAJ0_SPHTD
          Length = 245

 Score =  178 bits (451), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 65/245 (26%), Positives = 97/245 (39%), Gaps = 40/245 (16%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            S L+LRL GPMQAWG  +    R TG  P++SG++GLL A LG  R   + +  L+  +
Sbjct: 1   MSTLLLRLTGPMQAWGTQSRFSWRDTGLEPSKSGVIGLLCAALGRPRS--APVDDLA-RL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLG-AREDYRG-------LKSHETIQTWREYLCD 113
           +  VR D           T   D+HT  G  R    G         +     + R YL D
Sbjct: 58  RMGVRVDR--------EGTMHVDFHTAGGWHRRAEAGYGVPDPSGTARRPQISRRFYLAD 109

Query: 114 ASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDP------ 167
           A F V L        ++  L++A+  PR+  +LGR+S     P+ L       P      
Sbjct: 110 ADFLVGLE---GDEELLVLLDRALAAPRWQLFLGRKSFVPAAPVRLPDTPPWGPGLRPEP 166

Query: 168 -QKALLNYEPVGGDIYSEESV-----------TGHHLKFTARDEPMITLPRQFASREWYV 215
            + AL  Y  +G  +    +             G        D P+    R+F++R    
Sbjct: 167 LETALRTYPWLGYQLPHPRADAPDRLRLVLDAEGDDAADIRMDVPISFAERRFSTRAVRT 226

Query: 216 IKGGM 220
           +    
Sbjct: 227 VWIAT 231


>UniRef50_Q2JH27 CRISPR-associated protein, CT1976 n=6 Tax=Actinomycetales
           RepID=Q2JH27_FRASC
          Length = 276

 Score =  176 bits (447), Expect = 4e-43,   Method: Composition-based stats.
 Identities = 72/255 (28%), Positives = 96/255 (37%), Gaps = 52/255 (20%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
           R  L+LRLAGP+Q+WG  +    R T   PT+SG++GLL A  G +R D   ++ L  S+
Sbjct: 7   RHCLVLRLAGPLQSWGSRSMFNRRDTLTEPTKSGIIGLLAAAQGRRRTD--PIEDLL-SL 63

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGARED-------------YRGLKSHETIQTWR 108
              +R D+          T LRDYHTV   R                    +  T  T R
Sbjct: 64  TLGIRTDQ--------PGTLLRDYHTVSDYRGRPLPSAAVSAKGLQKPTSPAKHTHVTER 115

Query: 109 EYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASD-- 166
            YL DA F  AL        V++ L  A+  P +   LGRR+CP THPL L      D  
Sbjct: 116 FYLQDAVFVAALAAP---EPVLTTLADALRTPAFPLALGRRACPPTHPLLLVPDSEPDAA 172

Query: 167 -----PQKALLNYEPVGGDIYSEE----------------SVTGHHLKFTARDEPMITLP 205
                  + L          + +                 +V          D P    P
Sbjct: 173 LWSGSALEVLRQVPWQARPDHRDALARRRPPRLRRIDLPVTVDDPDGDDVRIDLPTTFDP 232

Query: 206 RQ--FASREWYVIKG 218
            Q  F SR  +    
Sbjct: 233 HQRGFTSRRVHQSWV 247


>UniRef50_B3E5U9 CRISPR-associated protein Cas5 family n=2 Tax=Desulfuromonadales
           RepID=B3E5U9_GEOLS
          Length = 271

 Score =  175 bits (445), Expect = 8e-43,   Method: Composition-based stats.
 Identities = 78/249 (31%), Positives = 111/249 (44%), Gaps = 35/249 (14%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             YL+ RL GP+ +WG+     +R +  +P +S LLGL+ A LGI+RD+     AL+   
Sbjct: 1   MKYLLFRLYGPLASWGEIAVGESRHSAVYPGKSALLGLIAAALGIRRDEEQRQAALASGY 60

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGA----------REDY--RGLKSHETIQTWRE 109
           +FAV+           +   LRDYHT              R D    G +   TI + RE
Sbjct: 61  RFAVKV--------ISTGHPLRDYHTAQAPDSVGKFVYRTRRDELVLGKERLGTILSSRE 112

Query: 110 YLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQK 169
           Y CDA   VA+     A   + E+ +A++KPR+  YLGR+SCP+  PL      A     
Sbjct: 113 YRCDAFSLVAVVAEDDAPYSLDEIREALMKPRFHLYLGRKSCPVAAPLNPLVRDAVGFGD 172

Query: 170 ALLNYE-------PVGGDIYSEESVTGHHL-------KFTARDEPMITLPRQFASREWYV 215
           AL +Y                +E V G  L       KF+  DE +    +Q   R ++ 
Sbjct: 173 ALDSYPYGALFVSSWLMKTAQKEIVEGGKLAEVPSLAKFSREDETVFAYNKQPV-RYYWE 231

Query: 216 IKGGMDVSQ 224
              G  VSQ
Sbjct: 232 GDAGDLVSQ 240


>UniRef50_D0MET6 CRISPR-associated protein Cas5 family n=1 Tax=Rhodothermus marinus
           DSM 4252 RepID=D0MET6_RHOM4
          Length = 252

 Score =  172 bits (436), Expect = 7e-42,   Method: Composition-based stats.
 Identities = 59/234 (25%), Positives = 95/234 (40%), Gaps = 27/234 (11%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L+LR   P+ ++G P  +       +P  S + GLL   LG    +T+ L+ L E +
Sbjct: 1   MEILLLRFDAPLMSFGAPIVDQYGFIQPYPALSMMTGLLANALGYTHAETARLERLQERL 60

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTV---LGAREDYRGLKSHETIQTW----------- 107
           ++AVR D             LRD+ TV        D R   +  T++T            
Sbjct: 61  RYAVREDRR--------GQQLRDFQTVDLSQPFLHDERAWTTRGTLETRQGGTASLGIHI 112

Query: 108 --REYLCDASFTVALWL-TPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQA 164
             R+Y  DA +TVAL L  P     +++LE+A+  P    ++GR+ C    PLF+G  +A
Sbjct: 113 RLRDYWADAVYTVALTLDPPDEPPTLADLEQALRFPARPLFIGRKPCLPAAPLFIGRVEA 172

Query: 165 SDPQKALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKG 218
           +D   AL    P+       +              P+  + R+   R     + 
Sbjct: 173 ADLLDALRR-APLDARADRADFYRVWWETGPDDPPPVEGI-RENLRRPVTDRRD 224


>UniRef50_Q1J367 CRISPR-associated protein, CT1976 n=1 Tax=Deinococcus geothermalis
           DSM 11300 RepID=Q1J367_DEIGD
          Length = 232

 Score =  171 bits (433), Expect = 2e-41,   Method: Composition-based stats.
 Identities = 60/229 (26%), Positives = 90/229 (39%), Gaps = 25/229 (10%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+LRL  PMQAWG  +    R T   P++SG+LGL  A LGI R D+    A    +
Sbjct: 1   MATLLLRLVAPMQAWGTRSRFDDRDTEAEPSKSGVLGLCAAALGIDRADSVEHLA---RL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
            F VR D               DYHT         G     T  T R YL DA+F   L 
Sbjct: 58  AFGVRVDR--------EGVAGTDYHTAQL----RPGNPRTRTDVTRRAYLADAAFWAGLE 105

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGG-- 179
                  ++++L+ A+  P +   LGR++ P + P+  G         AL     +    
Sbjct: 106 ---GDAGLLTDLDAALHNPHWPLSLGRKAFPPSLPICAGPPLEVSLWDALRTAPSLRWRD 162

Query: 180 -----DIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVS 223
                 +  +       L+  A       +P    +R  Y+ +  + V+
Sbjct: 163 DDEPYRLVLDREAVPQPLRAAASPSRRQDVPDGPFARRRYLSRDVLTVT 211


>UniRef50_C9M9R7 CRISPR-associated protein Cas5, Ecoli subtype n=1 Tax=Jonquetella
           anthropi E3_33 E1 RepID=C9M9R7_9BACT
          Length = 243

 Score =  170 bits (431), Expect = 3e-41,   Method: Composition-based stats.
 Identities = 58/222 (26%), Positives = 90/222 (40%), Gaps = 19/222 (8%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             +L+LR  GPM ++G    +  RP  RFP  S + GL+   LG    +T  LQAL + +
Sbjct: 1   MDFLVLRFRGPMMSFGDVAVDEQRPIDRFPGVSMVTGLVANALGWDWSETEKLQALQDRL 60

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHT----------VLGAREDYRGLKSHETIQTWREYL 111
             AVR D         +   LR+Y T          V  +    R L    T+Q +  Y 
Sbjct: 61  VLAVREDR--------AGERLREYQTVALPGKSGLFVTHSIPCSRNLDKPMTVQKYLSYW 112

Query: 112 CDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLG-TCQASDPQKA 170
            ++  T  + LT   T  + E+  A+ KP    +LGR++C  T P+F G    A  P++A
Sbjct: 113 ANSLITCFIALTGLGTPTLDEIACALKKPARPLFLGRKTCLPTEPVFRGEIFGAESPEEA 172

Query: 171 LLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASRE 212
           +L    +              +     D   +    +   R 
Sbjct: 173 VLRSCQLDKRPLKFVESPHSCVVEWPYDGRTVVSQSEIFERR 214


>UniRef50_D1Y486 Crispr-associated protein Cas5 n=1 Tax=Pyramidobacter piscolens
           W5455 RepID=D1Y486_9BACT
          Length = 269

 Score =  170 bits (430), Expect = 4e-41,   Method: Composition-based stats.
 Identities = 64/229 (27%), Positives = 93/229 (40%), Gaps = 36/229 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              LILRL GP+ A+G    +  RPT   P  S + GL+   LG    D   LQ L E +
Sbjct: 1   MDALILRLRGPLMAFGDVAVDEIRPTDLLPGLSEMTGLIANALGWTFQDVEKLQRLQERL 60

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYR------------GLKSHETIQTWRE 109
           + A R D         +   LRDY T   + ED              G K   T+Q +R 
Sbjct: 61  RLASREDR--------TGVPLRDYQTARLSSEDSLWRTDGIVAERGGGSKGEFTVQRYRH 112

Query: 110 YLCDASFTVALWLTP-HATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQ 168
           Y  DA+ TV + L P      + E+  A+  P    ++GR  CP + P+           
Sbjct: 113 YRADAAVTVLIALDPADEAPALEEIRDALRHPARPLFIGRIGCPPSQPIC---------- 162

Query: 169 KALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIK 217
                +EP G +I   +S+    +  T R        R+ ASR   +++
Sbjct: 163 -----FEPEGREIIHTDSLKDAIMHITPRAPLGAQTKREPASRNKVLVE 206


>UniRef50_B8IZA7 CRISPR-associated protein Cas5 family n=1 Tax=Desulfovibrio
           desulfuricans subsp. desulfuricans str. ATCC 27774
           RepID=B8IZA7_DESDA
          Length = 249

 Score =  169 bits (429), Expect = 5e-41,   Method: Composition-based stats.
 Identities = 53/214 (24%), Positives = 86/214 (40%), Gaps = 13/214 (6%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE----- 59
           L LRL  PM ++G  +    R T   P++S + G+L A  G+ R        L +     
Sbjct: 8   LALRLQAPMLSFGNESRFNRRCTASLPSKSVVAGMLCAAKGLHRGSVEEQAFLQQVAAIP 67

Query: 60  SVQFAV-RCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV 118
            +  A+ RC      D  ++     D+HTV G R+   G    +   T R YL D+SF V
Sbjct: 68  MLSVAIPRCLSANGKDWLLAAGRTVDFHTVQGTRKAAGG--IKDCHITTRHYLHDSSFAV 125

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTC--QASDPQKALLNYEP 176
            L        V+ +  +A+  P +  ++GR+ C  + P+F G    +A      L     
Sbjct: 126 FL---NGPYRVLEDAARALQNPVWGLWIGRKCCIPSAPVFGGLFSSEAVALNHMLDAPLE 182

Query: 177 VGGDIYSEESVTGHHLKFTARDEPMITLPRQFAS 210
                    S    +     + E  ++  R+FA 
Sbjct: 183 FFTHEREVHSFEDGNDTVPDQAESFLSAARRFAP 216


>UniRef50_B4UE71 CRISPR-associated protein Cas5 family n=2 Tax=Anaeromyxobacter
           RepID=B4UE71_ANASK
          Length = 246

 Score =  169 bits (428), Expect = 6e-41,   Method: Composition-based stats.
 Identities = 56/189 (29%), Positives = 81/189 (42%), Gaps = 6/189 (3%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M   LILR   P+ A+G    +     G FP  S + GL+   LG    D   L+AL   
Sbjct: 1   MLDALILRFDAPLLAFGGVAVDNHGEVGDFPGLSMVAGLIANALGYDHRDCDRLEALQRR 60

Query: 61  VQFAVRCDELILDDRRVSV-----TGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDAS 115
           ++ AVR D                  L    T  GA E   G  S  T   +R Y  DA 
Sbjct: 61  LRIAVRRDRSGQRLVDFQTVALGQPFLERGWTTRGAVEGRDGAFSDGTHIRYRAYWADAV 120

Query: 116 FTVALWLTPHAT-MVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNY 174
           +T+A+ L P A    +  +E+A+ +P    +LGR++C  + P+  G  Q      AL ++
Sbjct: 121 YTLAVTLDPPAESPGLDAVERALREPERPLFLGRKACLPSVPILAGRLQIPSLLAALASF 180

Query: 175 EPVGGDIYS 183
           E V  D + 
Sbjct: 181 ERVSKDRWE 189


>UniRef50_B8GIV3 CRISPR-associated protein Cas5 family n=1 Tax=Methanosphaerula
           palustris E1-9c RepID=B8GIV3_METPE
          Length = 257

 Score =  166 bits (421), Expect = 4e-40,   Method: Composition-based stats.
 Identities = 69/239 (28%), Positives = 94/239 (39%), Gaps = 37/239 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             YL   L G M +WG       RPT   PTRS +LGLL A LGI+RD+   L AL+ + 
Sbjct: 4   PEYLTFSLYGMMASWGDIAVGEYRPTADHPTRSAVLGLLAAALGIRRDEEERLAALTRAY 63

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRG-------------LKSHETIQTWR 108
           + A+R D             LRDYHT        +G              +   TI + R
Sbjct: 64  KVAIRVD--------APGMLLRDYHTTQVPSAAKKGRQYLTRKDELAAPREVLNTILSTR 115

Query: 109 EYLCDASFTVALWLTPHATM-VISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDP 167
           +Y CDA + V +W    A    +  L + +  P +T YLGR+SCPL  P+      A D 
Sbjct: 116 DYRCDAVYRVYIWCRDTAPPYSLKTLAEHLQHPVFTLYLGRKSCPLALPVNPEVKTAPDL 175

Query: 168 QKALLNYEPVGGDIY------SEESVTGHH---------LKFTARDEPMITLPRQFASR 211
             AL     +            + +V  +                DE +     QF  R
Sbjct: 176 LTALSEEREIELRFLGRVPGNRDSNVRAYWDCTEGIQAEGTSVRNDESLNRRRWQFGRR 234


>UniRef50_Q0AA33 CRISPR-associated protein Cas5 family n=2 Tax=Gammaproteobacteria
           RepID=Q0AA33_ALHEH
          Length = 242

 Score =  166 bits (421), Expect = 4e-40,   Method: Composition-based stats.
 Identities = 53/232 (22%), Positives = 78/232 (33%), Gaps = 24/232 (10%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              LILRL  P+ ++G    +   PT RFP RS L G+L   LG    DT +L +L   +
Sbjct: 1   MPCLILRLDAPLMSFGGVLVDQHNPTDRFPGRSMLTGMLANALGWHHQDTEALNSLQARI 60

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTV---------------LGAREDYRGLKSHETIQT 106
            +A R D        V    LRDY TV                       G       Q 
Sbjct: 61  SYAARWD--------VPPEPLRDYQTVDLGQTHLANPGWTTRGAPEHREGGTAKRGIHQR 112

Query: 107 WREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASD 166
            R Y  +   TVA+ + P    V + L  A+  P    ++GR++C    P+ L   ++ D
Sbjct: 113 DRHYWANGVMTVAVTVPPGEPNV-ATLAAALRHPARPLFIGRKACLPAAPVLLRVRESDD 171

Query: 167 PQKALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKG 218
               L +                     T          +       +  + 
Sbjct: 172 AYHVLASEPRDPRAAADTRFFEACWPPGTTAPATESRQRQNRTDDRDWRTQA 223


>UniRef50_B8FDI0 CRISPR-associated protein Cas5 family n=3 Tax=Bacteria
           RepID=B8FDI0_DESAA
          Length = 240

 Score =  166 bits (420), Expect = 5e-40,   Method: Composition-based stats.
 Identities = 68/243 (27%), Positives = 99/243 (40%), Gaps = 33/243 (13%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
            YL++ L  P+Q+WG  +  G R T  FPTRSG+LGLL   LG   +    L  L+   Q
Sbjct: 4   RYLLMWLEAPLQSWGADSKFGRRDTLPFPTRSGVLGLLLCALGASGEQKELLARLAPYGQ 63

Query: 63  FAVRC------DELILDDRRVSVTGLRDYHTVLGAREDYRGLKS--------------HE 102
             + C            ++      LRD+H V  A  D    +                 
Sbjct: 64  TVISCAGGRPGRSGGSPEKIPRQPLLRDFHMVGSAYNDKDPWERLHIPKTNEGKPAVGGG 123

Query: 103 TIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTC 162
              T+R YL DA F V L L P    +  +  +A+  P +  YLGR++C  T  ++ G  
Sbjct: 124 AKLTYRYYLQDARFAVILELPPD---LAEDFAQALQNPVWDIYLGRKNCAPTEFVYQGVF 180

Query: 163 ----QASDPQKALLNYEPVGGDIYSEESVTGHHL--KFTARDEPMITLP-RQFASREWYV 215
                A D   AL+  + +  D      V G H     T  D P+   P +++  R   V
Sbjct: 181 DSQKDAMDRAAALMEEKELMEDF---RVVDGEHPGEPITLNDVPLQFGPMKKYRDRRVTV 237

Query: 216 IKG 218
           I+ 
Sbjct: 238 IRN 240


>UniRef50_Q2FNU0 CRISPR-associated protein, CT1976 n=1 Tax=Methanospirillum hungatei
           JF-1 RepID=Q2FNU0_METHJ
          Length = 225

 Score =  158 bits (401), Expect = 9e-38,   Method: Composition-based stats.
 Identities = 51/214 (23%), Positives = 80/214 (37%), Gaps = 38/214 (17%)

Query: 35  GLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLG---- 90
            +LG++ A LGI+RDD  +   L     F+V   +            ++D+HT+      
Sbjct: 15  AVLGMVAAALGIRRDDEEAQNRLQAGYGFSVMVLQ--------PGIMIQDFHTIQSVHSS 66

Query: 91  ---------AREDYRGLKSHETIQTWREYLCDASFTVALWLTPHA--TMVISELEKAVLK 139
                     R D   L   ETI + REYLCD      +W+         + E+  +   
Sbjct: 67  SLKKMNHVMTRRDEMNLGDSETILSRREYLCDHVSVACVWIRDAESAQFSLEEIAASFRN 126

Query: 140 PRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNY-----------EPVGGDIYSEE--- 185
           P +  YLGR+SCP   P+     QA   + AL+ +            P    +Y E+   
Sbjct: 127 PVFCLYLGRKSCPPALPVHARVIQADSLKSALVQHIEGFDLLNGFRVPDRVSLYFEDGID 186

Query: 186 -SVTGHHLKFTARDEPMITLPRQFASREWYVIKG 218
                  +    RD  +     QF+ R  Y  + 
Sbjct: 187 IGFDDPVMVMKRRDNILSRSRWQFSDRNEYYARI 220


>UniRef50_UPI0001B51C2B CRISPR-associated Cas5 family protein n=1 Tax=Streptomyces
           viridochromogenes DSM 40736 RepID=UPI0001B51C2B
          Length = 278

 Score =  158 bits (399), Expect = 2e-37,   Method: Composition-based stats.
 Identities = 68/276 (24%), Positives = 100/276 (36%), Gaps = 72/276 (26%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M S L+LRLAGP+Q+WG       R T   PT+SG+ GL+ A LG+ R D   L AL++ 
Sbjct: 1   MTSVLLLRLAGPLQSWGALARFDRRDTLNRPTKSGVTGLVAAALGLDRADD--LGALTD- 57

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLG-------------AREDYRGLKSHET---- 103
           ++FAVR D           T +RD+H V                R   +   + ET    
Sbjct: 58  LRFAVRADR--------PGTAVRDFHIVGSGTYPLRPRDLITDHRRAEKAAAALETSTGP 109

Query: 104 --------------------------------------IQTWREYLCDASFTVALWLTPH 125
                                                 + T R YL DA+F  A+     
Sbjct: 110 VFGHLAARSVTKWYGAPKEIAPDPKTGVLLAGNTTRDAMMTTRWYLADAAFVAAVE--HP 167

Query: 126 ATMVISELEKAVLKPRYTPYLGRRSCPL----THPLFLGTCQASDPQKALLNYEPVGGDI 181
              ++  +  AV  P+   +LGR+SCP     +  +  GT +      ALL         
Sbjct: 168 DQNLLHRISHAVEHPKRLLWLGRKSCPPSGTISGGVHPGTAETILTTTALLPNATSPQPW 227

Query: 182 YSEESVTGHHLKFTARDEPMITLPRQFASREWYVIK 217
              E+  G        D+P+   P        +  +
Sbjct: 228 AWIEAAPGTPGAAQRTDQPVTYHPEHRTHTARWETR 263


>UniRef50_Q0BSC7 Putative uncharacterized protein n=1 Tax=Granulibacter bethesdensis
           CGDNIH1 RepID=Q0BSC7_GRABC
          Length = 225

 Score =  157 bits (396), Expect = 4e-37,   Method: Composition-based stats.
 Identities = 60/234 (25%), Positives = 93/234 (39%), Gaps = 41/234 (17%)

Query: 1   MRS--YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRD-DTSSLQAL 57
           M    +L+  LA  + + G+      R +  +PTRS ++GL+GA LGI+RD D S+L  L
Sbjct: 1   MMQQPFLVFGLAASLGSMGELAGHERRGSLIWPTRSAIIGLMGAALGIERDGDFSALDVL 60

Query: 58  SESVQFAVRCDELILDDRRVSVTGLRDYHTVLGARED------------YRGLKSHETIQ 105
           S  V                +   LRDYHT+                          T  
Sbjct: 61  SIDVAI------------FDAGAPLRDYHTIETIPSAAAKNPNSRPEALRDARGRTNTAI 108

Query: 106 TWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQAS 165
           T R+Y     + +A+         +  +  A+L+P +T Y+GR+SCPL  P      +A 
Sbjct: 109 THRDYRTSVFYGIAVRGAG-----LERIVAALLEPHFTLYVGRKSCPLAAPTGAKIVEAV 163

Query: 166 DPQKALLNYEPVGGDIYSEESVT------GHHLKFTARDEPMITLPRQFASREW 213
             + AL   E +   ++ +ESV                D P+      FA+R  
Sbjct: 164 SAEAAL---EHLKAPLWRKESVKAHLLVTDDPEGEVVTDVPLDRSSWHFATRRV 214


>UniRef50_C5V9N1 CRISPR-associated protein Cas5 n=1 Tax=Corynebacterium matruchotii
           ATCC 14266 RepID=C5V9N1_9CORY
          Length = 223

 Score =  155 bits (392), Expect = 9e-37,   Method: Composition-based stats.
 Identities = 57/234 (24%), Positives = 87/234 (37%), Gaps = 41/234 (17%)

Query: 1   MRSYLILRLAGPMQAWGQPTF-EGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE 59
           M   L +RLAGP+Q+W  P        T   PTRSGL+GLL    G  R +         
Sbjct: 1   MTEALYIRLAGPLQSWAGPAITGNFVRTEPRPTRSGLVGLLAGACGYGRGEYPEWLT--- 57

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHT----------------VLGAREDYRGLKSHE- 102
            + F +R D           T + D+HT                 +G R   + L S   
Sbjct: 58  QLHFQIREDNR--------GTLVDDFHTINPRDTEEEFRSRLLLAMGQRPTKKLLNSTPD 109

Query: 103 ----TIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLF 158
               T  T R Y+ D  F V +         +  L + + +P +  YLGR++   + P +
Sbjct: 110 GQGLTAITERTYIADGEFIVQIKAGSREHQEL--LAEKLQQPHFVTYLGRKAFAPSFPFY 167

Query: 159 LGTCQASDPQKALLNYEPVGGDIYSE--ESVTGHHLKFTARDEPMITLPRQFAS 210
           LG    + P   L     VGG+   +           +T    P++    Q+ +
Sbjct: 168 LG----AGPDDTLARIPTVGGEEPKKILRFYALDDYGYTTTTVPVVKDRNQWLT 217


>UniRef50_B4TTX2 CRISPR-associated protein Cas5 n=15 Tax=Enterobacteriaceae
           RepID=B4TTX2_SALSV
          Length = 241

 Score =  153 bits (388), Expect = 3e-36,   Method: Composition-based stats.
 Identities = 66/235 (28%), Positives = 95/235 (40%), Gaps = 33/235 (14%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M+ YL+ +L  P+ +WG+      R +   PTRS LLGLL A LGI+RD+ + L   +  
Sbjct: 1   MKEYLVFQLYAPLASWGEEASGEIRHSATVPTRSALLGLLAAALGIRRDEEARLNNFNRH 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL------------KSHETIQTWR 108
              AV                LRDYHTV   RE+ +                  T+ + R
Sbjct: 61  YHLAVHAL-------ASQDRWLRDYHTVSAPRENKKYRYYTRRDELTLAPDEVGTLISQR 113

Query: 109 EYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQA---S 165
           EY CD  + VA+  TP A   +SEL +A+L P +  YLGR+SCPL  PL           
Sbjct: 114 EYRCDGYWHVAISATPDAPHSLSELREALLTPHFPLYLGRKSCPLALPLAARLMTGTLKE 173

Query: 166 DPQKALLNYEPVGGDIYSEESV----TGHHLKFTA-------RDEPMITLPRQFA 209
               A+          ++             +           ++P+     QF 
Sbjct: 174 VFTHAVEEISAAELSGFTLREGICYWDDPDEESLVWQQKQHSNNQPVSRQRWQFG 228


>UniRef50_A9HLC6 CRISPR-associated protein Cas5 family n=11 Tax=Acetobacteraceae
           RepID=A9HLC6_GLUDA
          Length = 260

 Score =  152 bits (384), Expect = 8e-36,   Method: Composition-based stats.
 Identities = 64/259 (24%), Positives = 90/259 (34%), Gaps = 52/259 (20%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M  +L   +  PM ++G       R     P RS +LGL+ ACLG+ RDD  +  AL+  
Sbjct: 1   MGQFLTFAMVAPMASFGAIAVGERRDGWDRPARSAVLGLMAACLGLTRDDEDAQAALAAD 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLG--AREDYRGLKSHE----------TIQTWR 108
              A+ C              L DYHT     AR ++R     E          TI + R
Sbjct: 61  YGLAILC--------HAPGKLLTDYHTAQAAPARRNWRPATRAEELAASPGDLATILSRR 112

Query: 109 EYLCDASFTVALWLTPH-ATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDP 167
           +Y        A+W +   A   +  L+ A+ +P +TP LGRRSCP   PL          
Sbjct: 113 DYRMGTWHLGAVWTSGKTARWSLEALQAAMREPVFTPSLGRRSCPAGLPLAPSVTDGVSA 172

Query: 168 QKALLNYEPVGGDIYSEESVTG-------------------------------HHLKFTA 196
              LL+    G +                                           +   
Sbjct: 173 AAVLLDRHRNGPEAGLRIRHDSFRRQFAGASRSGGLLLVLDAVDMAEHGGGHTPLRREIR 232

Query: 197 RDEPMITLPRQFASREWYV 215
           RD+P+     QF  RE  V
Sbjct: 233 RDQPLSRRRWQFGLREEAV 251


>UniRef50_B6B783 CRISPR-associated protein Cas5, Ecoli subtype n=1
           Tax=Rhodobacterales bacterium Y4I RepID=B6B783_9RHOB
          Length = 232

 Score =  150 bits (378), Expect = 4e-35,   Method: Composition-based stats.
 Identities = 63/237 (26%), Positives = 87/237 (36%), Gaps = 39/237 (16%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRD-DTSSLQALSE 59
           M  YLI +L   + A G+      R +   P RS ++G LGA +G++RD D S L AL  
Sbjct: 1   MPEYLIFQLVAAIGAMGEFGGHDRRGSLTLPGRSAVIGTLGAAMGLRRDADFSGLDALGV 60

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGARED------------YRGLKSHETIQTW 107
           +V                     RDYHTV                      +   T  T 
Sbjct: 61  AVA------------SFGKTAPFRDYHTVQTVPSAAVKRPQSRPQALRDAGRKVNTTLTS 108

Query: 108 REYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDP 167
           R+Y  D  F VA+W        ++EL  A+  P +  +LGR+SCPL+ P       A+ P
Sbjct: 109 RDYRADCVFGVAIWGEG-----LAELASALSAPVFQTFLGRKSCPLSAPFDPQIVAAATP 163

Query: 168 QKAL--LNYEPVGGDIYSEESVTGHHLKF-------TARDEPMITLPRQFASREWYV 215
             AL  L   P  G    +  V              T  D  +      F    + V
Sbjct: 164 SAALSQLRLPPWIGAREMDMIVADEGTDLGAPSILETRHDRALDRTLWHFGKGRYAV 220


>UniRef50_B5GY62 Crispr-associated protein (Fragment) n=1 Tax=Streptomyces
           clavuligerus ATCC 27064 RepID=B5GY62_STRCL
          Length = 260

 Score =  145 bits (367), Expect = 7e-34,   Method: Composition-based stats.
 Identities = 60/186 (32%), Positives = 83/186 (44%), Gaps = 28/186 (15%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
            L+LRLAGP+Q+WG  +   +R TG  PT+SG++GLL A     R   + ++ L  +++ 
Sbjct: 85  VLLLRLAGPLQSWGSASAFNSRQTGAEPTKSGVIGLLAAA--DGRARGACIEDL-RALRL 141

Query: 64  AVRCDELILDDRRVSVTGLRDYHTVLGARED-------------YRGLKSHETIQTWREY 110
            VR D         S T LRDYHT    R                    +  T  T R Y
Sbjct: 142 GVRVDR--------SGTLLRDYHTASDHRGRPLAQAGVGAKGTQRPTSPAKYTQVTTRYY 193

Query: 111 LCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKA 170
           L DA F  AL        ++  L++AV  P +   LGRRSC  + PL LG        + 
Sbjct: 194 LQDAVFLAALA---GPRALLDRLDRAVRAPAFPLALGRRSCVPSLPLALGVHPG-SLGEV 249

Query: 171 LLNYEP 176
           L  +  
Sbjct: 250 LSTHPW 255


>UniRef50_C2KP44 Putative uncharacterized protein n=1 Tax=Mobiluncus mulieris ATCC
           35243 RepID=C2KP44_9ACTO
          Length = 245

 Score =  145 bits (367), Expect = 8e-34,   Method: Composition-based stats.
 Identities = 53/183 (28%), Positives = 75/183 (40%), Gaps = 22/183 (12%)

Query: 2   RSYLILRLAGPMQAW-GQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
            + + +RLAGP+Q+W G         T  +PTR  L GL+ ACLG  R          + 
Sbjct: 1   MTSVYIRLAGPLQSWAGAKVSGNISHTQDYPTRGSLEGLVAACLGCPRGKYPLW---FQD 57

Query: 61  VQFAVRCDELILDDRRVSVTGLRD--YHTVL-------GAREDYRGLK-----SHETIQT 106
           +QFAVR D            G+RD              G R   RGL        +T   
Sbjct: 58  LQFAVRVDSPGRICDDYQTIGVRDEDMQVATRLLTLLTGKRATNRGLAFIPDAQGKTTIV 117

Query: 107 WREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASD 166
            R  L DA F V +    H    + +L++A+  P +  YLGR++     P +LG  + S 
Sbjct: 118 RRTLLADAEFIVQIQCEGH----LEQLDQAISDPTFVSYLGRKAFAPGFPFYLGIGEDSA 173

Query: 167 PQK 169
              
Sbjct: 174 IDT 176


>UniRef50_B8IMR2 CRISPR-associated protein Cas5 family n=1 Tax=Methylobacterium
           nodulans ORS 2060 RepID=B8IMR2_METNO
          Length = 273

 Score =  142 bits (359), Expect = 6e-33,   Method: Composition-based stats.
 Identities = 51/187 (27%), Positives = 70/187 (37%), Gaps = 23/187 (12%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M + L+  L  P    G       R +   P RS +LGL+   LGI R D +   AL   
Sbjct: 1   MPAGLVFTLYAPFAGMGDVAVGEERGSFDRPARSAVLGLVAGALGIDRADEAGHAALDRG 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGA----------REDYRGLKSHETIQTWREY 110
            + A+R         R     + DYHTV             R +   +    T+ + R Y
Sbjct: 61  YRLALRL--------RTPGCLVEDYHTVQAPPVDRKARWATRREALAVAGLNTLVSRRAY 112

Query: 111 LCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFL----GTCQASD 166
             D    V L +          L  A+ +P + PYLGR+SCPL  PL      G  +   
Sbjct: 113 RADPIVDVVL-IHVDEGPTPEALATALRRPTFAPYLGRKSCPLGLPLRPLWAEGVTRVGS 171

Query: 167 PQKALLN 173
              AL  
Sbjct: 172 LLAALDE 178


>UniRef50_Q2RXJ5 CRISPR-associated protein, Cas5e family n=5 Tax=Proteobacteria
           RepID=Q2RXJ5_RHORT
          Length = 249

 Score =  142 bits (358), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 51/210 (24%), Positives = 81/210 (38%), Gaps = 8/210 (3%)

Query: 1   MRSY--LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALS 58
           M  +  LI+ L  P+ A+G    +    T  FP  S L GL    LG +R +    Q L 
Sbjct: 1   MPEHRWLIVHLEAPLLAFGGVAIDNVGVTRDFPAASMLTGLFANALGWRRTEWERHQRLQ 60

Query: 59  ESVQFAVRCDELIL-----DDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCD 113
           + + FA R +         D +   ++      T  G  E   G       +  R+Y  D
Sbjct: 61  DRLIFAARRERENPTGVLTDTQNAKLSKTERGWTTWGEPEGRDGASYGAPHRRRRDYHGD 120

Query: 114 ASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFL-GTCQASDPQKALL 172
           AS  VAL L       + +L  A+ +P    ++GR+SC  + PL       A+   +AL 
Sbjct: 121 ASVVVALRLDAAEEPALDDLAAALDRPARPLFIGRKSCVPSRPLRGKEFVVAATAYQALQ 180

Query: 173 NYEPVGGDIYSEESVTGHHLKFTARDEPMI 202
                G D   + +       +   + P+ 
Sbjct: 181 ALRSDGNDRQRDGAAAERRAVWPVGEGPVD 210


>UniRef50_Q6NEQ9 Putative uncharacterized protein n=1 Tax=Corynebacterium
           diphtheriae RepID=Q6NEQ9_CORDI
          Length = 242

 Score =  138 bits (349), Expect = 1e-31,   Method: Composition-based stats.
 Identities = 49/184 (26%), Positives = 75/184 (40%), Gaps = 22/184 (11%)

Query: 1   MRSYLILRLAGPMQAW-GQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE 59
           M     +RL+GP+Q+W G         T   PT S L GLL   LG +R +  +      
Sbjct: 1   MIESAYIRLSGPLQSWAGSVVTGNIVRTEPRPTFSSLRGLLAGALGARRGEWPNWLD--- 57

Query: 60  SVQFAVRCDE-LILDDRRVSVTGLRDYHTVLGAREDYRGLKSH-------------ETIQ 105
            V+F VR D   I+ +   ++  L +  T        +G K++              T  
Sbjct: 58  DVEFWVREDRKPIVVNEFQTINPLPEVETFRKRLLIAQGRKANSAKALTFTPDAQGGTSI 117

Query: 106 TWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQAS 165
             R YL D  + V +  + H    + E+E A   P +  YLGR++     P +LG   A 
Sbjct: 118 VNRTYLADGEYLVRVTSSTH----MDEIENAFSSPAFVTYLGRKAFYAEFPFYLGRGSAD 173

Query: 166 DPQK 169
             +K
Sbjct: 174 AFEK 177


>UniRef50_B5F422 CRISPR-associated protein Cas5 n=59 Tax=Enterobacteriaceae
           RepID=B5F422_SALA4
          Length = 248

 Score =  136 bits (342), Expect = 6e-31,   Method: Composition-based stats.
 Identities = 69/255 (27%), Positives = 101/255 (39%), Gaps = 39/255 (15%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M  YL+ +L GPM +WG       R +   P+RS LLGLL A LGI+RD+   L A +  
Sbjct: 1   MSQYLVFQLHGPMASWGVDAPGEVRHSHELPSRSALLGLLAAALGIRRDEEERLNAFNRH 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL-----------KSHETIQTWRE 109
            QF        L     +    RDYHTV   +E  +             +    + + R+
Sbjct: 61  YQF--------LLCASGNPRWARDYHTVQMPKEVRKARYFSRREELQDPELLSALISRRD 112

Query: 110 YLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQK 169
           Y  DA + +A+  TP A   +++L+ A+  P +  YLGR+S PL  PL     + S    
Sbjct: 113 YYTDAWWMIAVSATPDAPYTLAQLQAALQHPVFPLYLGRKSHPLALPLAPQLLEGSAADV 172

Query: 170 ALLNYEPVGGDIYSEESV----------TGHHLKFT------ARDEPMITLPRQFASREW 213
               Y        + +             G H   T       RD P+      F  R  
Sbjct: 173 LREAYRWYQDQFNALKLPLPRLQNECWWEGEHDGLTASKILRRRDMPLSRQQWLFGERSV 232

Query: 214 ----YVIKGGMDVSQ 224
               ++ K    +SQ
Sbjct: 233 NQGPWLRKEDACISQ 247


>UniRef50_B6XT64 Putative uncharacterized protein n=2 Tax=Bifidobacterium
           RepID=B6XT64_9BIFI
          Length = 212

 Score =  136 bits (342), Expect = 7e-31,   Method: Composition-based stats.
 Identities = 49/196 (25%), Positives = 76/196 (38%), Gaps = 28/196 (14%)

Query: 39  LLGACLGIQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL 98
           +L +  G  R+D   ++ L   + F VR ++            +RD  T           
Sbjct: 1   MLASAQGRTRED--PIEDLL-GISFGVRVEQR--------GRVIRDLQTEKSLTRKRNSR 49

Query: 99  K-SHETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPL 157
           K   E   T+R YL DA F VAL        V+  L++A+  P++  YLGRRSCP  +PL
Sbjct: 50  KFDKEMPLTYRYYLADACFLVAL---GADRSVLEMLDEAIHSPKWPLYLGRRSCPPNYPL 106

Query: 158 FLGTCQA-SDPQKALLNYEPVGGDIYSEE----------SVTGHHLKFTARDEPMITLP- 205
            LG      D ++AL +      + Y                      T  D P+     
Sbjct: 107 SLGIHDEYEDIRQALNSETWHASEWYRRRYRYPDLEIVCDAEKGENITTQSDLPLSFSRE 166

Query: 206 -RQFASREWYVIKGGM 220
            R++A+R  +  +   
Sbjct: 167 GRRYANRAVHRYRIPN 182


>UniRef50_B6IWM3 CRISPR-associated protein, CT1976 family n=1 Tax=Rhodospirillum
           centenum SW RepID=B6IWM3_RHOCS
          Length = 280

 Score =  135 bits (340), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 57/208 (27%), Positives = 84/208 (40%), Gaps = 31/208 (14%)

Query: 3   SYLILRLAGPMQAWGQPTFEG----TRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALS 58
           ++L   LA P  AWG  +        + T   P+RS L GLLGA LG++R   + L  LS
Sbjct: 6   AHLCFTLAAPYGAWGAASQSSATTAWKATELDPSRSALTGLLGAALGLER---AHLGRLS 62

Query: 59  ESVQFAVRCDELILDDRRVSVTGLRDYHTVLGA---------------REDYRGLKSHET 103
           E+++FAVR       D +       DYHT+  A               R    G K    
Sbjct: 63  EALRFAVRTGIRPTRDPQP------DYHTISRAHRPEGREHWSRFEELRPALAGGKQEGA 116

Query: 104 IQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQ 163
           + + REY     +TVA+     A + +  L +A+  P +  Y GR++C L  P       
Sbjct: 117 LLSRREYWSLGLWTVAVATLNPAGVPLDRLAQALRTPHWPLYAGRKACTLGLPPDPEVRT 176

Query: 164 ASDPQKALLNYEPVGGDIYSEESVTGHH 191
              P   LL+Y         +  +    
Sbjct: 177 GPGPLSVLLDYGW---PWQRKPGLDRPL 201


>UniRef50_C2GEY8 CRISPR-associated protein n=1 Tax=Corynebacterium glucuronolyticum
           ATCC 51866 RepID=C2GEY8_9CORY
          Length = 242

 Score =  134 bits (337), Expect = 2e-30,   Method: Composition-based stats.
 Identities = 48/189 (25%), Positives = 75/189 (39%), Gaps = 37/189 (19%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTR-PTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE 59
           M S   +RL+GP+Q+W   +  G    T   PT +GL GLL   LG +RD+         
Sbjct: 1   MPSSTFIRLSGPIQSWAGQSVSGNFIRTNPIPTLTGLRGLLAGALGARRDEIPEW---IS 57

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKS------------------- 100
            V+F+VR D+        + + + D+ T+    E++   +                    
Sbjct: 58  KVRFSVREDQ--------TGSFVDDFQTIGSREEEWDFRRRIAILQGMKARSIKQLSFKP 109

Query: 101 --HETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLF 158
                    R YL +A F V +    H      E++ A   P +  YLGR++ P   P +
Sbjct: 110 AVGANAVVRRTYLSEAEFIVRVTDERHT----EEIDHAFSSPVFATYLGRKAFPAAFPFY 165

Query: 159 LGTCQASDP 167
           LGT      
Sbjct: 166 LGTGNEDVL 174


>UniRef50_C0W6U0 CRISPR-associated Cas5 family protein n=1 Tax=Actinomyces
           urogenitalis DSM 15434 RepID=C0W6U0_9ACTO
          Length = 201

 Score =  133 bits (334), Expect = 5e-30,   Method: Composition-based stats.
 Identities = 50/193 (25%), Positives = 75/193 (38%), Gaps = 39/193 (20%)

Query: 39  LLGACLGIQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL 98
           +L A +G +R D   ++ L  S++F VR D+          T LRD+HT           
Sbjct: 1   MLAAAVGRRRTD--PIEDLL-SLRFGVRKDQ--------PGTVLRDFHTARTLDGKQ--- 46

Query: 99  KSHETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLF 158
                  + R YL DA +  A+        ++  L+ AV  P +  YLGRRSCP + PL 
Sbjct: 47  ---SMPLSERYYLADAVYLAAIE---GEKTLLEGLDVAVRHPVFPLYLGRRSCPPSQPLS 100

Query: 159 LGTCQASDPQKALLNYEPVGGDIYSEESV----------------TGHHLKFTARDEPMI 202
           LG   A    +AL +      D +                           +T  D P+ 
Sbjct: 101 LGIRHA-SLLQALTDEPWQAADWFRLRQDNSFRAEIVIDAASLAPDERGSGYTTLDSPVS 159

Query: 203 TLPRQ--FASREW 213
             PR+  + +RE 
Sbjct: 160 FDPRRRDYQAREV 172


>UniRef50_B8IJS9 CRISPR-associated protein Cas5 family n=1 Tax=Methylobacterium
           nodulans ORS 2060 RepID=B8IJS9_METNO
          Length = 253

 Score =  129 bits (325), Expect = 5e-29,   Method: Composition-based stats.
 Identities = 51/244 (20%), Positives = 81/244 (33%), Gaps = 34/244 (13%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           MR +L+L L  P+QAWG    +   P   FP  + + GL+   LG  R D   L+AL E 
Sbjct: 1   MREHLLLLLEAPLQAWGGVLVDAYGPVDEFPAATLVGGLVANALGYDRADWQRLEALQER 60

Query: 61  VQFAVRCDELI---LDDRRVSVTGLRDYHTVLGAREDYRGLKS--HETIQTWREYLCDAS 115
           +              D++   +       T  G  E   G         + +R+Y  D  
Sbjct: 61  LVVGAAVLRRGSTITDNQNAKLEKGDVGWTTRGRPEGRGGGAEAYKSPHRRFRDYHADTL 120

Query: 116 FTVALWLTPHAT-MVISELEKAVLKPRYTPYLGRRSCPLTH-PLFLGTCQASDPQKAL-- 171
             VAL L P      +  +   +  P    +LGR+ C  +   ++    +A    KAL  
Sbjct: 121 ALVALRLDPEDEKPDLDAIAHTLEWPERPLFLGRKPCLPSRSIVWPERMRAETLLKALNL 180

Query: 172 -------------------------LNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPR 206
                                      +    G+  S   V     +    D P+    R
Sbjct: 181 GAAMLVAAESANPKLRLELDAGPWRARWPEREGNAPSSRLVEVCDDRDFRNDVPVGLRRR 240

Query: 207 QFAS 210
           +  +
Sbjct: 241 RVGT 244


>UniRef50_Q3AA65 CRISPR-associated protein Cas5, Hmari subtype n=1
           Tax=Carboxydothermus hydrogenoformans Z-2901
           RepID=Q3AA65_CARHZ
          Length = 248

 Score =  118 bits (296), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 45/235 (19%), Positives = 78/235 (33%), Gaps = 33/235 (14%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGR------FPTRSGLLGLLGACLGIQRDDTSSL 54
           MR  ++  + GP              T        FP R+ L G++ A LG+ +D   SL
Sbjct: 1   MRKVIVFEIRGP------AAHFRKFYTNSSSLSYAFPARTTLAGIIAAVLGLPKDSYYSL 54

Query: 55  ---QALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAR--EDYRGLKSHETIQTWRE 109
                   +++      +++   + V    L++ +   G         L        +R 
Sbjct: 55  LTGNKAHYALRLMTPVRKIMQTVKFVRTKTLKEVNGSGGPTMIPTEIILPVRGRELIYRV 114

Query: 110 YLCDASFTVALWLTPHATMVISELEKAV-LKPRYTPYLGRRSCPLTHPL---FLGTCQAS 165
           Y                     EL K + L P++  YLGR            F GT   +
Sbjct: 115 Y-----------FYHDDPSFQEELAKQLALGPKFPVYLGRSEFLAKIDFLGVFPGTALET 163

Query: 166 DPQKALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLP-RQFASREWYVIKGG 219
           +    ++N E +  +     ++ G  L++     P    P R  AS    V + G
Sbjct: 164 NFVDTVVNLELLKDEELLFSTLHGEDLRYLKEKMPFSFNPDRSIASTASVVYEIG 218


>UniRef50_D1N0K0 Putative uncharacterized protein n=1 Tax=Victivallis vadensis ATCC
           BAA-548 RepID=D1N0K0_9BACT
          Length = 239

 Score =  115 bits (287), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 39/242 (16%), Positives = 69/242 (28%), Gaps = 36/242 (14%)

Query: 2   RSYLILRLAGPMQAWGQP--TFEGTRPTGRFPTRSGLLGLLGACLGI--QRDDTSSLQAL 57
            S LI  LAG M  W     +       G  P    L G++GA LG    R   +     
Sbjct: 1   MSILIFELAGEMAMWRNVYESMGSYSCLGPAPGN--LAGVIGAALGFASPRSQAAEKPDA 58

Query: 58  SESVQFAVRCDELILDDRRVSVTGLRDYHTV---LGAREDYRGLKSHETIQTWR------ 108
            +   +        +    ++     D+H     +G          +   +  R      
Sbjct: 59  KQLKNWDKAGLPWPVSPELLAWEETNDFHVACRWIGKFPKRVPWNINGCKEINRSDNLRL 118

Query: 109 --EYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSC------------PLT 154
             + + D ++ VA+ L  +       +  A+ KP +   LG   C               
Sbjct: 119 QQQVILDPAYEVAVALPAYEA---ERVAAALRKPAFPLCLGASFCRAIVRNVRIEDAVPE 175

Query: 155 HPLFLGTCQASDPQKALLNYEPV--GGDIYSEESVTGHHLKFTARDEPMITLPRQFASRE 212
            P +          +A      +   G  +      G+ +  T     +I    +   R 
Sbjct: 176 SPFWAFRTDGGALGEATPFSRHIVNPGSCFERIRSDGYWIYPTPDQPGVIAA--EPLVRG 233

Query: 213 WY 214
           W 
Sbjct: 234 WV 235


>UniRef50_A0LM54 Putative uncharacterized protein n=1 Tax=Syntrophobacter
           fumaroxidans MPOB RepID=A0LM54_SYNFM
          Length = 210

 Score =  103 bits (257), Expect = 5e-21,   Method: Composition-based stats.
 Identities = 38/196 (19%), Positives = 72/196 (36%), Gaps = 39/196 (19%)

Query: 46  IQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQ 105
           ++R D +       +++  VR D              +D+ T         G  S   + 
Sbjct: 26  LRRGDLA-------ALRMGVRVDR--------EGLLRKDFQTAQNVIVA--GGGSVGDLV 68

Query: 106 TWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFL--GTCQ 163
           + R +L DA+F V L       M++  L  ++  PR+  +LGR+S   + P ++  G  +
Sbjct: 69  SNRYFLSDAAFLVGLE---GDFMLLHRLHASLAHPRWPVFLGRKSYVPSIPPYIKNGLLE 125

Query: 164 ASDPQKALLNYEPV---GGDIYSEESVTGHH--------------LKFTARDEPMITLPR 206
            ++   AL ++ P+          + V                       RD+PM     
Sbjct: 126 GAELMSALASFTPLISVEELAARRKRVESGRRVERTRFVLESASPTHEIRRDQPMSFALG 185

Query: 207 QFASREWYVIKGGMDV 222
           Q    + +V+   +DV
Sbjct: 186 QRVFHDRFVVTEYLDV 201


>UniRef50_UPI0000F51765 hypothetical protein Faci_00030 n=1 Tax=Ferroplasma acidarmanus
           fer1 RepID=UPI0000F51765
          Length = 237

 Score =  103 bits (257), Expect = 5e-21,   Method: Composition-based stats.
 Identities = 21/149 (14%), Positives = 52/149 (34%), Gaps = 21/149 (14%)

Query: 1   MRSYLILRL--AGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALS 58
           M+   ++R+   G + ++  P       T   P ++ ++G++ A +G  RDD   +++L 
Sbjct: 1   MKEIKLIRINAYGIINSFRIPLHMTIHDTLDLPVKTHIIGMIAAAMGYLRDDKEKIESLY 60

Query: 59  ESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV 118
           ++    +           + +   +     +         K++ TI     Y+       
Sbjct: 61  KNTSIGIYGTSYSKFYDLIRIYKYKGKEVEVSLVNRQINYKNNYTI-----YI------- 108

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLG 147
                      + E+   +  P +   LG
Sbjct: 109 -------ENNNLEEIYNFLKNPVFALSLG 130


>UniRef50_B0K553 CRISPR-associated protein Cas5, Hmari subtype n=4
           Tax=Thermoanaerobacter RepID=B0K553_THEPX
          Length = 236

 Score = 95.0 bits (235), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 36/225 (16%), Positives = 67/225 (29%), Gaps = 40/225 (17%)

Query: 16  WGQPTFEGTRPTGR------FPTRSGLLGLLGACLGIQRDD-TSSLQALSESVQFAVR-- 66
           WG+        T         P R+ + G++ A LG +RD     L A  E++  AVR  
Sbjct: 7   WGKFAHFRKFYTNSSSLTYSVPPRTTVEGMIAALLGYERDTYYEKLNA--ENLYVAVRKM 64

Query: 67  --CDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTP 124
               +++     +  T L + H      +    L   ++   +R Y+             
Sbjct: 65  SKTKKIMQSVNYIKATTLGELHFPKQHTQIPFELLISDSKIRYRFYI-----------IH 113

Query: 125 HATMVISELEKAV--LKPRYTPYLGRRSCPLTHPL--FLGTCQASDPQKALLN-----YE 175
               +  E+++ +    P +  Y G      + P   ++   +      A        Y 
Sbjct: 114 KDENIFREIKERLFKKAPVFPLYFG------SAPFSCYIDYVEEVTWDWATSEDFQDIYS 167

Query: 176 PVGGDIYSEESVTGHHLKFTARDEPMITL-PRQFASREWYVIKGG 219
            +  D   E  +            P      R       YV +  
Sbjct: 168 VMPSDKIKEIDIKNMKGYLLKERMPRDFGIDRTIKEVTTYVYEDV 212


>UniRef50_B5IGN1 CRISPR-associated protein Cas5 n=1 Tax=Aciduliprofundum boonei T469
           RepID=B5IGN1_9EURY
          Length = 236

 Score = 94.3 bits (233), Expect = 3e-18,   Method: Composition-based stats.
 Identities = 23/150 (15%), Positives = 50/150 (33%), Gaps = 21/150 (14%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGI-QRDDTSSLQALSES 60
              L  +L     ++ +        T   P  + ++GLLG+ LG+  R+  +    L++ 
Sbjct: 1   MEVLTAKLRAISVSFRRILDFNYHRTYPLPPPTTIVGLLGSALGLSDRELWNEYNGLND- 59

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWR--EYLCDASFTV 118
           + FAV                 +D  ++   +             + R   +     +  
Sbjct: 60  ISFAVLSLR--------KPGFAKDMWSIQKIKNGR---------ISERSPYFRELLFYPE 102

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGR 148
            + +    +  +  +  A+  P Y   LGR
Sbjct: 103 YVLIFNGDSKSLECVRDALNNPEYALSLGR 132


>UniRef50_Q1AZD3 CRISPR-associated protein, Cas5h family n=1 Tax=Rubrobacter
           xylanophilus DSM 9941 RepID=Q1AZD3_RUBXD
          Length = 258

 Score = 91.2 bits (225), Expect = 3e-17,   Method: Composition-based stats.
 Identities = 45/241 (18%), Positives = 75/241 (31%), Gaps = 37/241 (15%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           LI  L G    + +     +  +  FP R+ L GL+   +G +RD  +   +L E  Q A
Sbjct: 7   LIFDLCGAYGMFRKFYTNSSSLSYPFPPRTTLAGLIAGMMGCERDSYAEDLSL-ERCQIA 65

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETI-------------QTWREYL 111
           V     +    +     + + H        + G      +               +R Y 
Sbjct: 66  VSVITPVRRVMQQVNYVMTEGHVWTKNTGGFDGSSGPIQVPVEWVFPEVGHRELRYRVY- 124

Query: 112 CDASFTVALWLTPHATMVISELEKAVLK--PRYTPYLGRRSCP-------LTHPLFLGTC 162
                      T      +  L + +    P Y PYLG   CP             LG  
Sbjct: 125 ----------ATHEDRGWLKRLAEILEGGVPIYPPYLGMSECPGRVEHVATLEGWGLGHR 174

Query: 163 QASDPQKALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDV 222
           +   P + +L  E V G    EE V     +       +    R  A+ +    + G  +
Sbjct: 175 EDELPVRTVLPSEAVSGPPRLEEGVQIVKERI---PLALDERRRLIAAADVLYNRAGPHI 231

Query: 223 S 223
           +
Sbjct: 232 T 232


>UniRef50_B1I5P1 CRISPR-associated protein Cas5 n=2 Tax=Clostridia
           RepID=B1I5P1_DESAP
          Length = 238

 Score = 77.7 bits (190), Expect = 3e-13,   Method: Composition-based stats.
 Identities = 49/215 (22%), Positives = 75/215 (34%), Gaps = 38/215 (17%)

Query: 13  MQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDELIL 72
           M ++ +P     + T   P  + L GL GA  G+   +    Q  S         D L+ 
Sbjct: 1   MASFRRPLDHNYQRTLPLPPPTTLFGLAGAARGL--AEEELWQEASPL------RDLLVA 52

Query: 73  DDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPHATMVISE 132
                     RD  TV+  + +    +S      +RE L +A F +   L      +++E
Sbjct: 53  TLALQKPGLARDMWTVMKIKNNKLAERSPY----FREILFNARFMI---LYGGPEELLAE 105

Query: 133 LEKAVLKPRYTPYLGR-------------RSCPLTHPLFLGTCQASDPQKALLNYEPVGG 179
           L++A L P Y   LGR              +C    PLF GT    D Q     + P  G
Sbjct: 106 LQQAFLDPTYPLSLGREDELIVVEELGRGETC-PGAPLFSGTVIPGDLQGLRFKWVPRPG 164

Query: 180 DIYSEESVTGHHL---------KFTARDEPMITLP 205
             +   +V    L         ++     P   LP
Sbjct: 165 IAFEPPAVETMPLAFEVDKRGIRYPLNPRPFTFLP 199


>UniRef50_D1CHV1 CRISPR-associated protein Cas5 n=1 Tax=Thermobaculum terrenum ATCC
           BAA-798 RepID=D1CHV1_THET1
          Length = 264

 Score = 62.7 bits (151), Expect = 9e-09,   Method: Composition-based stats.
 Identities = 34/234 (14%), Positives = 63/234 (26%), Gaps = 45/234 (19%)

Query: 1   MR-SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQR-----DDTSSL 54
           M    +I  LAG    + +     +  +  FP R+ L GL+   +G +R          L
Sbjct: 1   MPNKMIIFDLAGAYAMFRKFYTNSSSLSYPFPPRTVLAGLIAGIMGYERQGHRNTYAEHL 60

Query: 55  QALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSH------------- 101
                 +  +VR    +    +     + + +        + G +               
Sbjct: 61  APGVADIALSVRV--PVRRVMQTVNYVMTEGNVWSRNAGGFDGSRERTLTPVEWVFPASG 118

Query: 102 ETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLK-PRYTPYLGRRSCPL------- 153
                +R YL           T      +      +     Y PYLG   CP        
Sbjct: 119 RRQLRYRVYL-----------THRDEGWLERFAGYLRSGAVYPPYLGMTECPAVIEPVAE 167

Query: 154 THPLFLGTCQASDPQKALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQ 207
                LG  +   P   ++N      D   +  +     +      P+     +
Sbjct: 168 VEDWELGVREEVLPISTVIN-----ADKIVDLPLPDADAQIVKERMPIALDNDR 216


>UniRef50_A5D0Y3 Putative uncharacterized protein n=1 Tax=Pelotomaculum
           thermopropionicum SI RepID=A5D0Y3_PELTS
          Length = 242

 Score = 59.2 bits (142), Expect = 9e-08,   Method: Composition-based stats.
 Identities = 46/224 (20%), Positives = 72/224 (32%), Gaps = 21/224 (9%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
             L+  + G +  + QP    T  T  FP R  + GLL + LG+  DD +    L E   
Sbjct: 4   QVLVFSIKGSLAHFRQPDTTATHATYPFPPRPTIHGLLASVLGLDFDDEAGAAFLHEEHF 63

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWL 122
             +   + +                 +  +    G        T  E +    + V    
Sbjct: 64  VGLSLLKPVRTVCA---------QMSMHGKGFTGGGGDSFNRLTTIELVVSPHYLVYYTG 114

Query: 123 TPHATMVISELEKAVL--KPRYTPYLGRRSCPLTHPLFLGTCQ----ASDPQKALLNYEP 176
           +      + EL + +   +  Y  YLG   C LT P+F G       A   ++ L     
Sbjct: 115 SR-----LGELAERIRTGQSVYHTYLGSAYC-LTFPVFHGLYPLLEVAPGEEEPLPCSSV 168

Query: 177 VGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGM 220
           V   +  E  V        AR  P   +  +F  R   VI    
Sbjct: 169 VPQGVIQEILVEPGGNYAVARALPYRHVGGRFFERTLNVIYEVN 212


>UniRef50_A3DHS3 CRISPR-associated protein Cas5 n=3 Tax=Clostridium thermocellum
           RepID=A3DHS3_CLOTH
          Length = 241

 Score = 57.7 bits (138), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 33/146 (22%), Positives = 52/146 (35%), Gaps = 17/146 (11%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              LI+ L     ++  P  +    T   P  S + G+ GA LG+  +D     AL+   
Sbjct: 1   MYGLIVTLYAKTASFRDPGAQLYHETMSLPPPSTITGIAGAALGLSFED-----ALAFMK 55

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           + AV        + R      +D        +   G  ++  I   R +L D    V ++
Sbjct: 56  ENAVMVGCNGSSEGRG-----KDLW---NYTKIKSGEITNAIII--RNFLADLK--VEIF 103

Query: 122 LTPHATMVISELEKAVLKPRYTPYLG 147
                  VI+ L  A   P Y   LG
Sbjct: 104 FACEKREVITRLADAFENPVYAITLG 129


>UniRef50_D1B1G1 CRISPR-associated protein Cas5 n=1 Tax=Sulfurospirillum deleyianum
           DSM 6946 RepID=D1B1G1_SULD5
          Length = 237

 Score = 57.7 bits (138), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 28/147 (19%), Positives = 54/147 (36%), Gaps = 18/147 (12%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGA-CLGIQRDDTSSLQALSES 60
              +   + G + ++  P F     T   P ++ ++GLL    L  Q++    L    E 
Sbjct: 1   MEAIRFEVEGLLNSFRVPFFRTYHKTFLAPPKTTIIGLLCNIALKSQKEFFEILN--QEL 58

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           +  +V  DE+            +D  +     +   G          R+ L  + +T+ L
Sbjct: 59  IDVSVIIDEING--------KTKDLWSYKTLEKGNMGKS-----VIRRDKLFLSKYTIYL 105

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLG 147
            +      +  E+  A+  P+ TP LG
Sbjct: 106 SIKNK--TLFDEIYSALKNPKNTPALG 130


>UniRef50_A7ZDW7 Crispr-associated protein Cas5 n=3 Tax=Campylobacter
           RepID=A7ZDW7_CAMC1
          Length = 236

 Score = 57.3 bits (137), Expect = 4e-07,   Method: Composition-based stats.
 Identities = 38/206 (18%), Positives = 66/206 (32%), Gaps = 23/206 (11%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGT------RPTGRFPTRSGLLGLLGACLGIQRDDTSSLQ 55
            S +  RL      +G               T   P ++ ++G LGA +G   +D   L 
Sbjct: 1   MSIVAFRL------FGDYAHFSHPATIYSSLTYPVPPKTTIMGFLGAVIG--EEDYFKLS 52

Query: 56  ALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDAS 115
            +  SV+   +  +       +      + H   G +         E  Q +RE +C  S
Sbjct: 53  NIQYSVKIDRQILKKSFVFNGIKFALSSNMHIEEGYQNAK------EKKQFYRELICSPS 106

Query: 116 FTVALWLTPHATMVISELEKAVL--KPRYTPYLGRRSCPLTHPLF-LGTCQASDPQKALL 172
           + V L L         ++   +   K  +TPYLG   C        +  C+     ++ +
Sbjct: 107 YVVFLNLENLEQSYQDKIISNLKEHKTAFTPYLGINFCIADFSWIDIKICEKISQDESFI 166

Query: 173 NYEPVGGDIYSEESVTGHHLKFTARD 198
           N   +  D   E       L      
Sbjct: 167 NTFTLMDDFVFEGINENAKLTTARMP 192


>UniRef50_A7HLK6 CRISPR-associated protein Cas5, Hmari subtype n=2
           Tax=Thermotogaceae RepID=A7HLK6_FERNB
          Length = 236

 Score = 56.9 bits (136), Expect = 5e-07,   Method: Composition-based stats.
 Identities = 33/244 (13%), Positives = 64/244 (26%), Gaps = 62/244 (25%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGR------FPTRSGLLGLLGACLGIQRDDTSSL- 54
             +L+  +       G+        T         P R+ L G++ A LG +RD    + 
Sbjct: 1   MEFLVFDIK------GKFAHFRKFYTNSSSLSYSIPPRTTLEGIIAAILGFERDSYYEIL 54

Query: 55  --QALSESVQFAVRCDELILDDRRVSVTGLR-----DYHTVLGAREDYRGLKSHETIQTW 107
             Q L+  ++ A    ++I     +           D HT     +    + +      +
Sbjct: 55  NAQKLNIGLKKATPTRKIIQTLNYIKAKTPSNVYDPDEHT-----QIPFEIITSNDKVIY 109

Query: 108 REYLCDASFTVALWLTPHATMVISELEKAVLKPRYT--PYLGRRSCPLTHPLFLGTCQAS 165
           R Y           +      ++ +LE  +   ++   PY G        P  +      
Sbjct: 110 RVY-----------VNHVDQTIMEDLEYRLKNNKFCYIPYFG------VAPFNISI---- 148

Query: 166 DPQKALLNYEPVGGDIYSEESV----------TGHHLKFTARDEPMITLPRQFASREWYV 215
           D +           D     SV              +       P          R    
Sbjct: 149 DLKGKFQAEPKFSEDFVKVSSVIRRNLISSLKVEEEVILLKEKMPRDFSR----ERTVIE 204

Query: 216 IKGG 219
           ++  
Sbjct: 205 MEDY 208


>UniRef50_C7P9L3 CRISPR-associated protein Cas5 n=2 Tax=Methanocaldococcus
           RepID=C7P9L3_METFA
          Length = 258

 Score = 56.5 bits (135), Expect = 6e-07,   Method: Composition-based stats.
 Identities = 23/170 (13%), Positives = 50/170 (29%), Gaps = 27/170 (15%)

Query: 2   RSYLILRLAGP-MQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
              L  R  G    ++ +P       T + P  + + GL+   LG+ RD           
Sbjct: 1   MWGLKFRCEGIYFVSFRKPVTTSLSLTYKLPPFTAIRGLIANALGMPRDSFEIQNWFKIG 60

Query: 61  VQFAVRCDELILDDRRVSVTGLR--------DYHTVLGAREDYRGLKSHETIQT------ 106
           ++   + +      + + +   +         +  +  ++         E +        
Sbjct: 61  MRVEGKIEIGREMAKFLKMISRKSCYRCENCRFEKIADSKPKKCPNCGKENLVKVEKMIY 120

Query: 107 ---------WREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLG 147
                     RE+L    + + L         I ++  A+  P    YLG
Sbjct: 121 ERAFPSSPMHREFLIMPKYWIYLV---GEEKKIKKIYYALKSPERPLYLG 167


>UniRef50_D0MJ68 CRISPR-associated protein Cas5 n=1 Tax=Rhodothermus marinus DSM
           4252 RepID=D0MJ68_RHOM4
          Length = 236

 Score = 55.0 bits (131), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 36/144 (25%), Positives = 54/144 (37%), Gaps = 17/144 (11%)

Query: 8   RLAGPMQAWGQPTFE--GTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAV 65
            LAGP+ ++  P     G +PT   P  S + GL+ A LG   D         E++QFA 
Sbjct: 12  ELAGPVASFRYP-HFLIGRQPTYPMPPPSTIYGLISAALGRFPD--------PEALQFAY 62

Query: 66  RCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPH 125
           R +        V        +T        + L++   I   RE+L     T+ +     
Sbjct: 63  RFECARHRVDDVETIWFVQPNTATRGEAARKNLEATSNILP-REWLVHPRLTLYVTGDE- 120

Query: 126 ATMVISELEKAVLKPRYTPYLGRR 149
               +  L +A   P Y   LGR 
Sbjct: 121 ----LEALYRAFRSPCYILTLGRS 140


>UniRef50_B7R550 CRISPR-associated protein Cas5 n=1 Tax=Thermococcus sp. AM4
           RepID=B7R550_9EURY
          Length = 275

 Score = 54.6 bits (130), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 27/159 (16%), Positives = 50/159 (31%), Gaps = 17/159 (10%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACL----GIQRDDTSSLQALS 58
             L++ L  P   +  P       T   P +S ++G+L   L    G +R          
Sbjct: 4   KTLLIELFQPFAQYRNPFTFYYAQTYPLPPKSTIIGMLQNALNDWYGNERGIDEWWN--- 60

Query: 59  ESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL------KSHETIQTWRE-YL 111
             ++ +V      +      +         +        L           + + R   L
Sbjct: 61  --LRVSVHGGFESVFWNYQQLIKATKTGISIVRFRGKPTLWNQKLPLYGFPVTSQRSPVL 118

Query: 112 CDASFTVALW-LTPHATMVISELEKAVLKPRYTPYLGRR 149
               F   L+ L       +SE+++A+ +PR    LGR 
Sbjct: 119 QQELFNGWLYILLKGEEEFLSEIKEALERPRKVISLGRS 157


>UniRef50_C9RCY2 CRISPR-associated protein Cas5, Hmari subtype n=2
           Tax=Thermoanaerobacteraceae RepID=C9RCY2_AMMDK
          Length = 266

 Score = 54.2 bits (129), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 36/160 (22%), Positives = 56/160 (35%), Gaps = 25/160 (15%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M +  +  L GP   + +     +  +  FP R+ L+G + A LG +RD       LSE+
Sbjct: 1   MVNVAVFDLVGPFAHFRKYYTNSSSLSYAFPPRTALMGTVAAVLGWERDSYYEKLGLSEA 60

Query: 61  VQFA----VRCDELILDDRRVSVT-----GLRDYHTVLGAREDYRGLKSHETIQT--WRE 109
            +FA    V    LI     +         LR    V G +     L    T  +  +R 
Sbjct: 61  -RFAVVIKVPVRRLIQTVNYIRTKEEDLNRLRKLEAVKGTQVPLELLLPGGTASSLCFRV 119

Query: 110 YLCDASFTVALWLTPHATMVISELEKAVL--KPRYTPYLG 147
           Y                  V  EL + +   +  +  YLG
Sbjct: 120 YFA-----------HRDDQVTRELAERLAAGRSYFPLYLG 148


>UniRef50_B5YBH8 CRISPR-associated protein Cas5, Hmari subtype n=1 Tax=Dictyoglomus
           thermophilum H-6-12 RepID=B5YBH8_DICT6
          Length = 250

 Score = 53.1 bits (126), Expect = 8e-06,   Method: Composition-based stats.
 Identities = 24/157 (15%), Positives = 54/157 (34%), Gaps = 24/157 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES- 60
              ++  L G M  + +     +  +  FP R+ ++GL+   LG +RD    + +  ++ 
Sbjct: 1   MKVIVFDLLGKMAHFRKFYTNSSSLSYHFPPRTTIVGLIAGLLGYERDTYYEIFSTDKAK 60

Query: 61  VQFAVR--------CDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLC 112
           +   V+            +  +    +   R  HT     E        E    +R    
Sbjct: 61  ITIGVKSPLRKILQVVNYVWAENVKQLNQSRGQHT-QIPLEIIFPQDMKE-DICYR---- 114

Query: 113 DASFTVALWLTPHATMVISELEKAVLK--PRYTPYLG 147
                  ++       ++ +L+  ++     + PYLG
Sbjct: 115 -------IFFHHKDEKIMEDLKNKLVNFDFCFPPYLG 144


>UniRef50_C6QNG6 CRISPR-associated protein Cas5, Hmari subtype n=1 Tax=Geobacillus
           sp. Y4.1MC1 RepID=C6QNG6_9BACI
          Length = 244

 Score = 52.7 bits (125), Expect = 8e-06,   Method: Composition-based stats.
 Identities = 28/157 (17%), Positives = 50/157 (31%), Gaps = 25/157 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              LI  L G M  + +     +  +  FP R+ ++G++   LG++RD    + +  +  
Sbjct: 1   MKMLIFDLIGKMGHFRKIDTNSSSLSYAFPPRTTIVGMIAGILGMERDSYYEVFS-PDQC 59

Query: 62  QFAVRCDELILDDRRVSVTGLR---------DYHTVLGAREDYRGLKSHETIQTWREYLC 112
           Q A+     I    +                  HT     E        E    +R Y  
Sbjct: 60  QIAISVRTPIRKVMQTVNYMFVKSKAHLNNSGGHT-QIPLEFVLPG-GEEANLRYRIY-- 115

Query: 113 DASFTVALWLTPHATMVISELEKAVLKP--RYTPYLG 147
                     +     V   +++ +      Y PYLG
Sbjct: 116 ---------FSHSDRSVYESVKERIQSGRYVYPPYLG 143


>UniRef50_O27159 Putative uncharacterized protein n=1 Tax=Methanothermobacter
           thermautotrophicus str. Delta H RepID=O27159_METTH
          Length = 269

 Score = 52.7 bits (125), Expect = 9e-06,   Method: Composition-based stats.
 Identities = 24/153 (15%), Positives = 47/153 (30%), Gaps = 11/153 (7%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L + +  P   +  P       T     +S + G+L    G  R     +  +S S+
Sbjct: 1   METLAVEIFQPFAQFRNPFTFDYAQTYPLSPKSTVTGMLQNATG--RYYDQDISEISVSI 58

Query: 62  QFAVRCDELILDDRRVSVTGLRDYH-----TVLGAREDYRGLKSHETIQTWREYLCDASF 116
              +           +       YH             Y   K  +   ++++ L +  +
Sbjct: 59  H-GLFESTFWNYQSFIVGDIALKYHHNKLKLWNKGYPLYSVNKKSQRSPSYQQELFNGHY 117

Query: 117 TVALWLTPHATMVISELEKAVLKPRYTPYLGRR 149
            + L        +I E+  ++ KP     LGR 
Sbjct: 118 YIFLR---GDDDIIEEVCDSLRKPTKPLSLGRS 147


>UniRef50_D1A6P6 Metal dependent phosphohydrolase n=1 Tax=Thermomonospora curvata
           DSM 43183 RepID=D1A6P6_THECD
          Length = 1027

 Score = 51.9 bits (123), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 26/147 (17%), Positives = 41/147 (27%), Gaps = 26/147 (17%)

Query: 8   RLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVRC 67
           +L  P+ ++  P F G       P  S L G+L A  G            +E V   V  
Sbjct: 14  QLYAPVASFRDPMFPGVTRCLPVPPPSTLRGMLAAATGRP----------AEPVVLGV-- 61

Query: 68  DELILDDRRVSVTGLRDYH-TVLGAREDYRGLK----SHETIQTWREYLCDASFTVALWL 122
                            YH           G +            R +L     T+ + +
Sbjct: 62  ----CAYAEGRGVDTETYHPIAADGSNPAIGGRVRPGKGGMTIRERPFLTGVHITLWVPM 117

Query: 123 TPHATMVISELEKAVLKPRYTPYLGRR 149
                     +  A+ +P +   LGR 
Sbjct: 118 PDG-----ERIATALRRPTWGLRLGRS 139


>UniRef50_A4J1X9 CRISPR-associated protein Cas5, Hmari subtype n=1
           Tax=Desulfotomaculum reducens MI-1 RepID=A4J1X9_DESRM
          Length = 242

 Score = 51.5 bits (122), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 31/151 (20%), Positives = 61/151 (40%), Gaps = 9/151 (5%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDD-TSSLQALSE 59
           M   +  RL+G    + +     +  +   P R+ LLG+LGA LG+++D     L+ L  
Sbjct: 1   MMKLIAFRLSGRFGHFLRAEAGTSALSYPVPPRTVLLGILGAVLGLEKDLPQELLEPLHI 60

Query: 60  SVQFAVRCDELILDD-RRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV 118
           ++   V          R+     L     V   ++  +  K        +E+L + ++T+
Sbjct: 61  ALAGPVPQSHWHKAKLRKDPPEALP--QVVKNNQKQEKTTKPEMATLITQEWLFNPAYTI 118

Query: 119 ALWLTPHATMVISELEKAVLKP--RYTPYLG 147
            + L         +LE+ + +    + P LG
Sbjct: 119 WVALP---EPYHQQLEQRLKERCWHFQPCLG 146


>UniRef50_O57910 Putative uncharacterized protein PH0171 n=1 Tax=Pyrococcus
           horikoshii RepID=O57910_PYRHO
          Length = 227

 Score = 51.1 bits (121), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 33/218 (15%), Positives = 68/218 (31%), Gaps = 25/218 (11%)

Query: 1   MRSYLILRLAG-PMQA-WGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALS 58
           M   L L +   P+QA +  P       T  FP ++  +G+L  C+G+        + L 
Sbjct: 1   MSELLGLIVDARPLQAHFRIPHTSLLLDTYPFPPKTTAVGMLAGCMGLG---EEGFKKLL 57

Query: 59  ESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV 118
           E +++ V  +             + +   +              +    R  L    F +
Sbjct: 58  EKIKYGVIIE--------DPGEKIEEVSVIYK-------NPYSPSYPITRVSLYKPRFRM 102

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGRRS--CPLTHPLFLGTCQASDPQKALLNYEP 176
                     VI E  + +L P++ PY+G            ++      + ++ +L    
Sbjct: 103 FFA---GEERVIEEAYEGLLDPKFVPYMGDSESLFYPGKKRYVEVVDVQEGKEDILRSVI 159

Query: 177 VGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWY 214
                     +    L     + P+    +  + R  Y
Sbjct: 160 PEVKFKEFVPLRRKVLVPKVYEAPVKFTYKGKSRRAVY 197


>UniRef50_Q2NH81 Putative uncharacterized protein n=1 Tax=Methanosphaera stadtmanae
           DSM 3091 RepID=Q2NH81_METST
          Length = 235

 Score = 50.4 bits (119), Expect = 4e-05,   Method: Composition-based stats.
 Identities = 30/150 (20%), Positives = 50/150 (33%), Gaps = 16/150 (10%)

Query: 16  WGQPTFEGTRPT------GRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDE 69
           WG   +     T        FP+R+ + G +   LG  R+    L    E+ +  ++   
Sbjct: 9   WGDYAYFRRGYTTTSTLTYPFPSRTTIAGFIAGILGYPRNSYYDL-FQKENSKIGLKIIN 67

Query: 70  LILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPHATMV 129
            I   R          +T               T     E+L +  + + L L      +
Sbjct: 68  PIKKTRINLNYI----NTKNSMLLSEIKGNGKRTQVPA-EFLKNVKYRIYLSL--DDEEI 120

Query: 130 ISELEKAVL--KPRYTPYLGRRSCPLTHPL 157
           +++L   +   K  YTPYLG   C     L
Sbjct: 121 MNKLYNTLKEHKSVYTPYLGITECLANFSL 150


>UniRef50_B1LAM2 CRISPR-associated protein Cas5, Hmari subtype n=2 Tax=Thermotoga
           RepID=B1LAM2_THESQ
          Length = 220

 Score = 50.4 bits (119), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 32/170 (18%), Positives = 60/170 (35%), Gaps = 23/170 (13%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L+  ++     + +P    +  T  FP R+ LLGL+G  LG        L +   +V
Sbjct: 1   MKVLVFDVSTSYALFRRPYTTTSSYTLPFPPRTALLGLVGCVLGY--STPEKLDSAKVAV 58

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           Q             +  +  LR   T     E  +  K+ +  +   + L + ++ V   
Sbjct: 59  QI------------KNPLKFLR---TGTNFVETKKDKKASKRTRISLQLLKNPAYRVFFS 103

Query: 122 LTPHATMVISELEKAVLK--PRYTPYLGRRSCPLTHPLFLGTCQASDPQK 169
                      L+  +      +TPYLG  S       ++G  +A+  + 
Sbjct: 104 WEDKD---FERLKNLLEHNETIFTPYLGVASFIAKLD-YVGEYEATRVED 149


>UniRef50_D2QT47 CRISPR-associated protein Cas5 n=1 Tax=Spirosoma linguale DSM 74
           RepID=D2QT47_9SPHI
          Length = 237

 Score = 49.2 bits (116), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 26/143 (18%), Positives = 42/143 (29%), Gaps = 21/143 (14%)

Query: 6   ILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGI-QRDDTSSLQALSESVQFA 64
            + L     ++  P F+    +   P  + L+GL GA LG+  R     L          
Sbjct: 5   TIELKSVTASFRNPEFQNFHKSFPLPPPTALIGLAGAALGLSPRMAQDFLD--------- 55

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTP 124
              ++             RD          Y  L    +    RE   +  +   L    
Sbjct: 56  --TNQFQAGVSGKGEGMTRDLW-------KYDRLTGTGSSIILREIYVNPHY--RLVFGS 104

Query: 125 HATMVISELEKAVLKPRYTPYLG 147
                + +L+ A   P Y   LG
Sbjct: 105 DNHEAVEQLKAAFDSPVYALTLG 127


>UniRef50_A3XI99 Putative uncharacterized protein n=1 Tax=Leeuwenhoekiella
           blandensis MED217 RepID=A3XI99_9FLAO
          Length = 243

 Score = 48.8 bits (115), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 24/148 (16%), Positives = 48/148 (32%), Gaps = 15/148 (10%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQ--RDDTSSLQALSE 59
               I+ +     ++  P F+    +   P  + ++G+ GA LG    R      ++  E
Sbjct: 1   MKNFIIEIQCQTASFRNPDFQNFHKSLELPPPTTVIGIAGAALGYSPLRAQEFFDESKFE 60

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
              +     +     +      +RD                 +     RE+L   +F +A
Sbjct: 61  IGIYGTYLGKCKDTWKYNKG--IRDM---------RLYDPGLDGSIIQREFLIFPTFIIA 109

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLG 147
              +      + +L KA   P Y   +G
Sbjct: 110 --FSSENIKAVEKLYKAFTSPVYALTMG 135


>UniRef50_C7NNV3 CRISPR-associated protein Cas5, Hmari subtype n=3
           Tax=Halobacteriaceae RepID=C7NNV3_HALUD
          Length = 264

 Score = 48.1 bits (113), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 38/213 (17%), Positives = 63/213 (29%), Gaps = 21/213 (9%)

Query: 5   LILRLAGPMQAWGQPTFEG---TRPTGRFPTRSGLLGLLGACLGIQRDDTSSL--QALSE 59
           L   + GP   WG          + T R   R+ + GL+ A LGI RD    L    +S 
Sbjct: 21  LSFEIRGP---WGHFRRVEGNVVKQTYRIVPRTTVAGLIAAVLGIDRDGYYDLFGPEVSA 77

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWRE-Y--LCDASF 116
                V     +        T   D  T L  R        + T    +  Y  L D ++
Sbjct: 78  IAIQPVEELRTVNMPMNTLSTAAGDL-TSLNPRGKISIKLPNPTKLRQQHNYEVLVDPAY 136

Query: 117 TVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEP 176
            + + L         +L + +         G+     +  L     +     +  +   P
Sbjct: 137 RIDVALADDERY--EQLRETLAA-------GKSHYVPSLGLSEYLAEIDYLGEFDVKPGP 187

Query: 177 VGGDIYSEESVTGHHLKFTARDEPMITLPRQFA 209
             G I  + +V           E    + +  A
Sbjct: 188 ASGTIAVDSAVPDAMDDVVLDPETRCQIEQSPA 220


>UniRef50_C8PE23 CRISPR-associated protein Cas5 n=1 Tax=Campylobacter gracilis
           RM3268 RepID=C8PE23_9PROT
          Length = 237

 Score = 48.1 bits (113), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 28/152 (18%), Positives = 56/152 (36%), Gaps = 10/152 (6%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              +   L+G    +  P    +  T   P ++ ++GLLGA +G    +   L  +  SV
Sbjct: 1   MDIIAFELSGDYAHFSHPATIYSSLTYPVPPKTAIMGLLGAIIG--EMNYFKLNDIGYSV 58

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
             + +  +  +    +        H   G         S E  Q ++E + D  + + + 
Sbjct: 59  ILSSQFRKKTMIFNGIKFALSSSMHIEQG------YQDSSEKKQFYKELIKDPRYVIFVD 112

Query: 122 LTPHATMVISELEKAVL--KPRYTPYLGRRSC 151
           L+         +  ++   +  +TPYLG   C
Sbjct: 113 LSALNASYKENIIDSLKAHRCVFTPYLGINFC 144


>UniRef50_B9MPU1 CRISPR-associated protein Cas5, Hmari subtype n=2 Tax=Clostridia
           RepID=B9MPU1_ANATD
          Length = 250

 Score = 47.3 bits (111), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 29/183 (15%), Positives = 57/183 (31%), Gaps = 36/183 (19%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGR------FPTRSGLLGLLGACLGIQRDDTSSLQ 55
             +L+  L       G+        T         P R+ + G++ A LG +RD    + 
Sbjct: 1   MKFLVFDLK------GKFAHFRKFYTNSSSLSYLVPPRTVIEGMVAAILGFERDSYYDMF 54

Query: 56  ALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLC--D 113
           + +E++  AV        ++   +    +Y       E        +      E L   +
Sbjct: 55  S-AENLLVAV-----QKLEKTYKIVQTVNYIKAQTISELKNPNTHTQVPL---EILAGYN 105

Query: 114 ASFTVALWLTPHATMVISELEKAVLK--PRYTPYLGRRSCPLTHPL-----FLGTCQASD 166
                 +++ P    + S L   +      +  Y G      + P      FLG  +A  
Sbjct: 106 GFVGFRVFVMPKDEKIYSFLRARLESGKSEFPIYFG------SAPFAAKIEFLGEFEACR 159

Query: 167 PQK 169
            + 
Sbjct: 160 WED 162


>UniRef50_B1B9K0 Crispr-associated protein Cas5, tneap subtype n=1 Tax=Clostridium
           botulinum C str. Eklund RepID=B1B9K0_CLOBO
          Length = 244

 Score = 47.3 bits (111), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 24/150 (16%), Positives = 54/150 (36%), Gaps = 11/150 (7%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQ-ALSES 60
              ++L++   +  + +PT    + T   P  S ++G++ A  G   D+   ++ ++  +
Sbjct: 1   MKAILLKVTQNLVNYKKPTSFQLKETYPLPPYSTVIGMVHAACGF--DEYKDMEVSIQGN 58

Query: 61  VQFAVRCDELILDDRRVSVTGLRDY-HTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
               V     +      +     D  H +    ED           +  E L D    + 
Sbjct: 59  YHSKV---NDLYTRYEFAGASYEDKRHNIKLKGEDKYYGAMRG--VSTCELLVDVELLIH 113

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRR 149
           +   P    +I  + + +  P+    +GRR
Sbjct: 114 I--KPKDENLIQIIYQNLKYPKEYLSIGRR 141


>UniRef50_A3DKB9 CRISPR-associated protein Cas5, Hmari subtype n=2 Tax=Clostridium
           thermocellum RepID=A3DKB9_CLOTH
          Length = 237

 Score = 46.9 bits (110), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 27/149 (18%), Positives = 53/149 (35%), Gaps = 26/149 (17%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSL-QALSESV 61
            YL+  ++     + +P    +  T   PTR+ + G++ A LG  ++D           +
Sbjct: 4   KYLVFDISASYGHFKKPYTTTSPLTYSIPTRTAVSGIIAAVLGFGKEDYQEHFTKPQAKI 63

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWR-----EYLCDASF 116
              +R            V  +R         E+    K    I   R     E+L DA +
Sbjct: 64  AIGIR----------NPVKKVR-------ISENLINTKKSMNIIHERTQIKIEFLKDACY 106

Query: 117 TVALWLTPHATMVISELEKAVLKPRYTPY 145
              ++ T     +   L++++ +   T Y
Sbjct: 107 --RIYFTHTDKQIYERLKESLKE-HRTVY 132


>UniRef50_C8VZL1 CRISPR-associated protein Cas5 n=1 Tax=Desulfotomaculum
          acetoxidans DSM 771 RepID=C8VZL1_DESAS
          Length = 253

 Score = 46.1 bits (108), Expect = 8e-04,   Method: Composition-based stats.
 Identities = 15/64 (23%), Positives = 29/64 (45%), Gaps = 1/64 (1%)

Query: 2  RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             +   L G M  + +     +  +   P R+ L+G++   LG +RD    + +L+ S 
Sbjct: 1  MKIISFHLRGKMAHFRRYYANSSALSYSIPPRTTLIGIVAGLLGWERDKYYEIFSLN-SC 59

Query: 62 QFAV 65
          + AV
Sbjct: 60 KVAV 63


>UniRef50_B1I4M5 CRISPR-associated protein Cas5 family n=1 Tax=Candidatus
           Desulforudis audaxviator MP104C RepID=B1I4M5_DESAP
          Length = 255

 Score = 46.1 bits (108), Expect = 8e-04,   Method: Composition-based stats.
 Identities = 23/153 (15%), Positives = 51/153 (33%), Gaps = 24/153 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFE--GTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE 59
                + +  P+ ++  P     G + +   P  S + G + + +G    +  +   +  
Sbjct: 1   MRVAKVHIEAPIASFRYP-HFLIGRQTSFDMPPPSTIYGHIASAVG----EWFNPATVKF 55

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREY---LCDASF 116
           + QF+           +   + L   H +    + ++  +    + T       L D  F
Sbjct: 56  AYQFS----------FQAKGSDLEHQHVITKGGQTFKWGERKYPVSTQAVVQPHLRDFLF 105

Query: 117 TVALWLTPHATMVISELEKAVLKPRYTPYLGRR 149
              L L  +      +L +A   P +   LGR 
Sbjct: 106 GCRLTLYLYPP----DLAEAFRNPVFCVILGRS 134


>UniRef50_Q3M7D6 Fruiting body developmental protein S-like protein n=3
           Tax=Cyanobacteria RepID=Q3M7D6_ANAVT
          Length = 210

 Score = 46.1 bits (108), Expect = 0.001,   Method: Composition-based stats.
 Identities = 22/142 (15%), Positives = 46/142 (32%), Gaps = 17/142 (11%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + + L++  P+  + Q        T   P  S + G+L + +G    +    +     +
Sbjct: 1   MTTIALKVEVPIACFRQSRAREYGETYPVPPPSTVYGMLLSLVG----EVDRYKHCGVKL 56

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
             A       L       T +R +H      +      S      ++E L +  F V + 
Sbjct: 57  AIA-------LLSEPEKSTVIRTFH----RFKTKNIHDSKNNKPDYQELLTNIEFIVWVD 105

Query: 122 LTPH--ATMVISELEKAVLKPR 141
                    ++  L +A+  P 
Sbjct: 106 AGVDKAKPNLVERLAEALTNPA 127


>UniRef50_C1DUR1 Crispr-associated protein Cas5, hmari subtype n=1
           Tax=Sulfurihydrogenibium azorense Az-Fu1
           RepID=C1DUR1_SULAA
          Length = 229

 Score = 45.7 bits (107), Expect = 0.001,   Method: Composition-based stats.
 Identities = 28/154 (18%), Positives = 52/154 (33%), Gaps = 27/154 (17%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPT------GRFPTRSGLLGLLGACLGIQRDDTSSLQ 55
              L+  +      WG         T         P  + + G++GA LGI + D   + 
Sbjct: 1   MEVLVFDV------WGDFGHFRKFYTTTSPLTFSIPPPTAVFGIIGAILGIDKKDYLKII 54

Query: 56  ALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDAS 115
             +E+ + A+   + +   R           T+          +         E+L DA 
Sbjct: 55  N-AETTKVAIEIVKPVKKIRF----------TINYIDTKVSFSRIKNRTPIRTEFLKDAH 103

Query: 116 FTVALWLTPHATMVISELEKAV--LKPRYTPYLG 147
           + + + L  +   +  EL+  +   K  YT  LG
Sbjct: 104 YRLYINL--NEENLFRELKDRIKERKTYYTVSLG 135


>UniRef50_A7BQN4 Protein containing DUF522 n=1 Tax=Beggiatoa sp. PS
           RepID=A7BQN4_9GAMM
          Length = 267

 Score = 45.7 bits (107), Expect = 0.001,   Method: Composition-based stats.
 Identities = 30/132 (22%), Positives = 56/132 (42%), Gaps = 16/132 (12%)

Query: 27  TGRFPTRSGLLGLLGACLGIQRDDTSSLQALS-ESVQFAVRCDELILDDRRVSVTGLRDY 85
           T  FP  + ++GLLGA LG  +++    + L  ++++  +R  +     R  ++  L   
Sbjct: 47  TYPFPPPTAIMGLLGAILGYSKEEY--HERLGWQTLRVGIRLLKPTQIFR-AAINLL--- 100

Query: 86  HTVLGAREDYRGLKSHETIQTWR---EYLCDASFTVALWLTPHATMVISELEKAVL--KP 140
            T  G    +R      +    R   E++   ++ + +   P    V S+L   +   + 
Sbjct: 101 QTKDGTDTFFRPKADKNSH--TRVPYEFVKSPAYRIYVMQLPD--NVASDLVAHLKTHRT 156

Query: 141 RYTPYLGRRSCP 152
            YTP LG  SC 
Sbjct: 157 VYTPVLGLASCL 168


>UniRef50_B8CYA3 CRISPR-associated protein Cas5 n=1 Tax=Halothermothrix orenii H 168
           RepID=B8CYA3_HALOH
          Length = 238

 Score = 45.4 bits (106), Expect = 0.002,   Method: Composition-based stats.
 Identities = 26/158 (16%), Positives = 55/158 (34%), Gaps = 19/158 (12%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
             L+ ++ G +  + +     +  T + P R+ L+G++ + L   RD    L +  ++ +
Sbjct: 5   QVLVFKIKGKIAHFKKYYSNKSSLTYKIPPRTVLMGIVASILEKPRDSYYELLSPQQA-K 63

Query: 63  FAVRCDELILDDRRVSVTGLRD-YHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           F V+ +               D  HT          L ++    +++ +           
Sbjct: 64  FGVKIESESYTHFECMNYLKEDGGHT---QVRLQLLLPANNM-LSYKVF----------- 108

Query: 122 LTPHATMVISELEKAVLKPR--YTPYLGRRSCPLTHPL 157
            T     ++ EL   +      Y  YLG+R    T   
Sbjct: 109 FTHQDESLLKELATKIKNKIYGYGIYLGQRQFRATAEF 146


>UniRef50_Q8PZD2 Putative uncharacterized protein n=1 Tax=Methanosarcina mazei
           RepID=Q8PZD2_METMA
          Length = 232

 Score = 45.0 bits (105), Expect = 0.002,   Method: Composition-based stats.
 Identities = 21/115 (18%), Positives = 43/115 (37%), Gaps = 20/115 (17%)

Query: 35  GLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGARED 94
            + GL+GA LGI + +   +   +  ++  ++    +           +D   +      
Sbjct: 34  AVKGLIGAVLGIDKTE---IYRNTLDLKIGIQVLSPVR----------KDMQVLKLVSMK 80

Query: 95  YRGLKSHETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLK--PRYTPYLG 147
                 +  +    E+L D  + + +   P     + ELE  +    P +TPYLG
Sbjct: 81  AEKDLFNFPV--NAEFLRDPEYRIFVSWLPDK---LDELEDRLQNQMPIFTPYLG 130


>UniRef50_A1ZVP9 Crispr-associated protein Cas5, tneap subtype n=1 Tax=Microscilla
           marina ATCC 23134 RepID=A1ZVP9_9SPHI
          Length = 218

 Score = 44.2 bits (103), Expect = 0.003,   Method: Composition-based stats.
 Identities = 23/124 (18%), Positives = 35/124 (28%), Gaps = 26/124 (20%)

Query: 26  PTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDY 85
           PT   P  S +LGL+ A  G       +   L     F                +   D 
Sbjct: 26  PTLEVPPVSTVLGLINAAAGH----YVAHSTLKLGYYF-------------EYQSKAVDL 68

Query: 86  HTV-LGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTP 144
            T+              ++    RE+L +A   + +           E+      P Y  
Sbjct: 69  ETIYQIGAHKGMPSNHAKSNIIRREFLFEAFLRLYVTS--------QEVADYFRSPVYPI 120

Query: 145 YLGR 148
            LGR
Sbjct: 121 VLGR 124


>UniRef50_A8F3P0 CRISPR-associated protein Cas5, Hmari subtype n=1 Tax=Thermotoga
           lettingae TMO RepID=A8F3P0_THELT
          Length = 230

 Score = 43.8 bits (102), Expect = 0.004,   Method: Composition-based stats.
 Identities = 26/150 (17%), Positives = 53/150 (35%), Gaps = 21/150 (14%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRD--DTSSLQALSE 59
              ++  + G    + +     +  +  FP R+ + GLLGA +GIQ +    S    + +
Sbjct: 1   MKVIVFDVKGKYALFRRNYTTSSSTSYNFPPRTSICGLLGAIMGIQNEATQFSKHLRIFD 60

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
           +   A+R    I               T+     + +  K+  T     E + +  + + 
Sbjct: 61  NAHIALRVLVPIRKT------------TMGVNYAETKSGKNQRTQII-LELIKEPVYRIY 107

Query: 120 LWLTPHATMVISELEKAVLKP--RYTPYLG 147
           +           +L   +      +TPYLG
Sbjct: 108 VS----EFSQFDQLRNHLENNTCVFTPYLG 133


>UniRef50_A4XGC7 CRISPR-associated protein Cas5 family n=1
          Tax=Caldicellulosiruptor saccharolyticus DSM 8903
          RepID=A4XGC7_CALS8
          Length = 275

 Score = 43.0 bits (100), Expect = 0.008,   Method: Composition-based stats.
 Identities = 14/53 (26%), Positives = 22/53 (41%), Gaps = 6/53 (11%)

Query: 1  MRSY------LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQ 47
          M+        L +++  P   +  P     R T   P  S +LGL+   LGI+
Sbjct: 1  MKETKNSIYALKIKIYQPQAHFRIPFSYQRRHTYPIPPYSTVLGLIANILGIK 53


>UniRef50_D1QSA9 CRISPR-associated protein Cas5, Tneap subtype n=1 Tax=Prevotella
           oris F0302 RepID=D1QSA9_9BACT
          Length = 224

 Score = 41.1 bits (95), Expect = 0.026,   Method: Composition-based stats.
 Identities = 29/155 (18%), Positives = 51/155 (32%), Gaps = 28/155 (18%)

Query: 2   RSYLILRLAGPMQAWGQP-TFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
                ++++    ++  P    G +PT   P  S +LGL+ AC G       +   +   
Sbjct: 1   MKVFRIKISAWTASFRYPNIISGYQPTLEVPPLSTILGLMNACAGR----YLNHADMEIG 56

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSH-ETIQTWREYLCDASFTVA 119
             F  R                 D  T+   + D    K   ++    R++L D +  + 
Sbjct: 57  YYFNYRSIS-------------NDLETIYQMKYDKGTAKKQVKSNVINRQFLFDNTLYIY 103

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLT 154
           +           +  K    P +   LGR SC L 
Sbjct: 104 IID--------KDFVKYFQTPAFQILLGR-SCDLA 129


>UniRef50_B9LWL0 CRISPR-associated protein Cas5, Hmari subtype n=1 Tax=Halorubrum
           lacusprofundi ATCC 49239 RepID=B9LWL0_HALLT
          Length = 265

 Score = 40.7 bits (94), Expect = 0.041,   Method: Composition-based stats.
 Identities = 36/220 (16%), Positives = 57/220 (25%), Gaps = 51/220 (23%)

Query: 16  WGQPTFEGT---RPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDELIL 72
           WG     G    + T R P R+ + G+L A +G  RD                  D    
Sbjct: 23  WGHFKRVGRSVTKQTYRIPPRTTVAGMLAAIVGSDRDSYY---------------DVFGA 67

Query: 73  DDRRVSVTGLRDYHTVLGAREDYRGLKS---HETIQTWREY------------------L 111
           D   +++T L D  TV                +T  + R Y                  L
Sbjct: 68  DTSAIAITPLFDIRTVNVPTTGLGTDPKQAVTKTAGSRRSYALTYQDTEGDRQIHAYELL 127

Query: 112 CDASF--TVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQK 169
            D  +   VA+    +   +   L+    +  Y P LG+                     
Sbjct: 128 TDPVYRIDVAVEDEAYYEKLERRLDN--EESYYPPSLGKSEYL--------CTVEDVETD 177

Query: 170 ALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFA 209
                         +  V G   +   +      + R  A
Sbjct: 178 VSPTELAEAEQYDVDSVVPGSLSEVIPQQGVTYDIERSPA 217


>UniRef50_A1HND7 CRISPR-associated protein Cas5 family n=1 Tax=Thermosinus
           carboxydivorans Nor1 RepID=A1HND7_9FIRM
          Length = 257

 Score = 40.0 bits (92), Expect = 0.063,   Method: Composition-based stats.
 Identities = 40/228 (17%), Positives = 72/228 (31%), Gaps = 23/228 (10%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTR-PTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             L + ++    ++  P     R PT   P  + + G L    G    +  +   L  S 
Sbjct: 6   DVLKIEMSAMTASFRYPHVMIGRLPTFEMPPPATIYGHLCGVWG----EWFNPGDLEFSY 61

Query: 62  QF---AVRCD-ELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFT 117
            F    +  D EL       S    +   T+ G  ++ +G  + +     R++L     T
Sbjct: 62  VFTHGGIGEDVELGHMIEFGSGRSEK---TLGGLPKNMKGSLNPQ----RRQFLFRPRMT 114

Query: 118 VALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLT--HPLFLGTCQASDPQKALLNYE 175
           + L        ++  LE+A   P +   LGR     T     +    QAS    A     
Sbjct: 115 LYLK---GDDKILQRLEQAFKSPAFAYILGRSQDLATVHSITWARLKQASGAFFANTLLP 171

Query: 176 PVGGDIYS--EESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMD 221
                  S          + +    EP+     +   R   +   G++
Sbjct: 172 WTLRQWVSVGRPVYMPKWINYHKLREPVFERYLEIDDRPLRIFGEGVE 219


  Database: uniref50.fasta
    Posted date:  Mar 8, 2010 10:38 AM
  Number of letters in database: 1,040,396,356
  Number of sequences in database:  3,077,464
  
Lambda     K      H
   0.308    0.142    0.427 

Lambda     K      H
   0.267   0.0438    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,436,281,571
Number of Sequences: 3077464
Number of extensions: 64330909
Number of successful extensions: 160290
Number of sequences better than 1.0e-01: 122
Number of HSP's better than  0.1 without gapping: 227
Number of HSP's successfully gapped in prelim test: 59
Number of HSP's that attempted gapping in prelim test: 159388
Number of HSP's gapped (non-prelim): 306
length of query: 224
length of database: 1,040,396,356
effective HSP length: 124
effective length of query: 100
effective length of database: 658,790,820
effective search space: 65879082000
effective search space used: 65879082000
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.1 bits)
S2: 91 (39.6 bits)
