BLASTP 2.2.22 [Sep-27-2009]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= batch____
         (224 letters)

Database: uniref50.fasta 
           3,077,464 sequences; 1,040,396,356 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q46898 Uncharacterized protein ygcI n=13 Tax=Proteobact...   278   7e-74
UniRef50_B7KJ26 CRISPR-associated protein Cas5 family n=1 Tax=Cy...   223   4e-57
UniRef50_D1NTI1 CRISPR-associated protein Cas5 n=1 Tax=Bifidobac...   220   2e-56
UniRef50_D1CGD4 CRISPR-associated protein Cas5 family n=6 Tax=Ba...   211   2e-53
UniRef50_Q12YA8 CRISPR-associated protein, CT1976-like n=1 Tax=M...   209   5e-53
UniRef50_Q314I4 CRISPR-associated protein, CT1976 n=1 Tax=Desulf...   209   7e-53
UniRef50_C2BET8 CRISPR-associated protein n=2 Tax=Firmicutes Rep...   205   8e-52
UniRef50_A3EQA4 CRISPR-ssociated protein, Cas5 n=3 Tax=Bacteria ...   205   8e-52
UniRef50_B0TDU1 Crispr-associated protein cas5 n=1 Tax=Heliobact...   199   5e-50
UniRef50_B8HWH8 CRISPR-associated protein Cas5 family n=1 Tax=Cy...   199   8e-50
UniRef50_Q04QB7 Putative uncharacterized protein n=2 Tax=Leptosp...   198   1e-49
UniRef50_D0Y918 CRISPR-associated protein Cas5 family n=2 Tax=De...   198   1e-49
UniRef50_Q0W584 Putative uncharacterized protein n=1 Tax=uncultu...   197   3e-49
UniRef50_D0WFC8 CRISPR-associated protein Cas5 n=1 Tax=Slackia e...   197   3e-49
UniRef50_B4S8P8 CRISPR-associated protein Cas5 family n=8 Tax=Ba...   195   8e-49
UniRef50_A1ARH6 CRISPR-associated protein, Cas5e family n=2 Tax=...   194   3e-48
UniRef50_C9M2Y8 CRISPR-associated protein n=1 Tax=Lactobacillus ...   193   4e-48
UniRef50_Q5YRB6 Putative uncharacterized protein n=1 Tax=Nocardi...   192   9e-48
UniRef50_D2RB02 CRISPR system CASCADE complex protein CasD n=3 T...   192   9e-48
UniRef50_A8SDR7 Putative uncharacterized protein n=1 Tax=Faecali...   191   1e-47
UniRef50_B2GBJ9 Putative uncharacterized protein n=1 Tax=Lactoba...   191   2e-47
UniRef50_A7BA63 Putative uncharacterized protein n=1 Tax=Actinom...   191   2e-47
UniRef50_Q2JWC5 CRISPR-associated protein Cas5, Ecoli subtype n=...   190   3e-47
UniRef50_Q1EQS9 CRISPR-associated protein n=3 Tax=Streptomyces R...   190   3e-47
UniRef50_A5GBK2 CRISPR-associated protein Cas5 family n=2 Tax=De...   189   5e-47
UniRef50_UPI0001AF1D4C CRISPR-associated protein, CT1976 n=1 Tax...   189   7e-47
UniRef50_C7MQD6 CRISPR-associated protein Cas5 n=1 Tax=Saccharom...   189   8e-47
UniRef50_A5UR14 CRISPR-associated protein, Cas5e family n=1 Tax=...   188   1e-46
UniRef50_B1VIY0 CRISPR-associated protein n=9 Tax=Actinomycetale...   186   4e-46
UniRef50_B0S4B6 Putative uncharacterized protein n=1 Tax=Finegol...   185   7e-46
UniRef50_Q1R114 CRISPR-associated protein, CT1976 n=1 Tax=Chromo...   185   8e-46
UniRef50_A6W168 CRISPR-associated protein Cas5 family n=6 Tax=Ga...   185   1e-45
UniRef50_Q47PI7 CRISPR-associated protein, Cas5e family n=12 Tax...   184   2e-45
UniRef50_A8M404 CRISPR-associated protein Cas5 family n=1 Tax=Sa...   184   3e-45
UniRef50_D1A6Q5 CRISPR-associated protein Cas5 family n=2 Tax=Ac...   183   4e-45
UniRef50_C5SD48 CRISPR-associated protein Cas5 family n=1 Tax=Al...   182   6e-45
UniRef50_C7LYW6 CRISPR-associated protein Cas5 family n=1 Tax=Ac...   182   6e-45
UniRef50_A1SV73 CRISPR-associated protein, Cas5e family n=2 Tax=...   182   6e-45
UniRef50_Q03C60 CRISPR-associated protein n=4 Tax=Lactobacillus ...   180   3e-44
UniRef50_C8XAY4 CRISPR-associated protein Cas5 family n=2 Tax=Ac...   180   3e-44
UniRef50_A8LYZ7 CRISPR-associated protein Cas5 family n=2 Tax=Ac...   180   4e-44
UniRef50_Q2RY19 CRISPR-associated protein, Cas5e family n=1 Tax=...   179   7e-44
UniRef50_C7MTB0 CRISPR-associated protein Cas5 n=1 Tax=Saccharom...   178   1e-43
UniRef50_D2L2X8 CRISPR-associated protein Cas5 family n=1 Tax=De...   178   1e-43
UniRef50_A8ZZ17 CRISPR-associated protein Cas5 family n=1 Tax=De...   178   1e-43
UniRef50_D1CAJ0 CRISPR-associated protein Cas5 family n=1 Tax=Sp...   178   1e-43
UniRef50_Q2JH27 CRISPR-associated protein, CT1976 n=6 Tax=Actino...   176   4e-43
UniRef50_B3E5U9 CRISPR-associated protein Cas5 family n=2 Tax=De...   175   8e-43
UniRef50_D0MET6 CRISPR-associated protein Cas5 family n=1 Tax=Rh...   172   7e-42
UniRef50_Q1J367 CRISPR-associated protein, CT1976 n=1 Tax=Deinoc...   171   2e-41
UniRef50_C9M9R7 CRISPR-associated protein Cas5, Ecoli subtype n=...   170   3e-41
UniRef50_D1Y486 Crispr-associated protein Cas5 n=1 Tax=Pyramidob...   170   4e-41
UniRef50_B8IZA7 CRISPR-associated protein Cas5 family n=1 Tax=De...   169   5e-41
UniRef50_B4UE71 CRISPR-associated protein Cas5 family n=2 Tax=An...   169   6e-41
UniRef50_B8GIV3 CRISPR-associated protein Cas5 family n=1 Tax=Me...   166   4e-40
UniRef50_Q0AA33 CRISPR-associated protein Cas5 family n=2 Tax=Ga...   166   4e-40
UniRef50_B8FDI0 CRISPR-associated protein Cas5 family n=3 Tax=Ba...   166   5e-40
UniRef50_Q2FNU0 CRISPR-associated protein, CT1976 n=1 Tax=Methan...   158   9e-38
UniRef50_UPI0001B51C2B CRISPR-associated Cas5 family protein n=1...   158   2e-37
UniRef50_Q0BSC7 Putative uncharacterized protein n=1 Tax=Granuli...   157   4e-37
UniRef50_C5V9N1 CRISPR-associated protein Cas5 n=1 Tax=Corynebac...   155   9e-37
UniRef50_B4TTX2 CRISPR-associated protein Cas5 n=15 Tax=Enteroba...   153   3e-36
UniRef50_A9HLC6 CRISPR-associated protein Cas5 family n=11 Tax=A...   152   8e-36
UniRef50_B6B783 CRISPR-associated protein Cas5, Ecoli subtype n=...   150   4e-35
UniRef50_B5GY62 Crispr-associated protein (Fragment) n=1 Tax=Str...   145   7e-34
UniRef50_C2KP44 Putative uncharacterized protein n=1 Tax=Mobilun...   145   8e-34
UniRef50_B8IMR2 CRISPR-associated protein Cas5 family n=1 Tax=Me...   142   6e-33
UniRef50_Q2RXJ5 CRISPR-associated protein, Cas5e family n=5 Tax=...   142   1e-32
UniRef50_Q6NEQ9 Putative uncharacterized protein n=1 Tax=Coryneb...   138   1e-31
UniRef50_B5F422 CRISPR-associated protein Cas5 n=59 Tax=Enteroba...   136   6e-31
UniRef50_B6XT64 Putative uncharacterized protein n=2 Tax=Bifidob...   136   7e-31
UniRef50_B6IWM3 CRISPR-associated protein, CT1976 family n=1 Tax...   135   1e-30
UniRef50_C2GEY8 CRISPR-associated protein n=1 Tax=Corynebacteriu...   134   2e-30
UniRef50_C0W6U0 CRISPR-associated Cas5 family protein n=1 Tax=Ac...   133   5e-30
UniRef50_B8IJS9 CRISPR-associated protein Cas5 family n=1 Tax=Me...   129   5e-29
UniRef50_Q3AA65 CRISPR-associated protein Cas5, Hmari subtype n=...   118   1e-25
UniRef50_D1N0K0 Putative uncharacterized protein n=1 Tax=Victiva...   115   2e-24
UniRef50_A0LM54 Putative uncharacterized protein n=1 Tax=Syntrop...   103   5e-21
UniRef50_UPI0000F51765 hypothetical protein Faci_00030 n=1 Tax=F...   103   5e-21
UniRef50_B0K553 CRISPR-associated protein Cas5, Hmari subtype n=...    95   2e-18
UniRef50_B5IGN1 CRISPR-associated protein Cas5 n=1 Tax=Acidulipr...    94   3e-18
UniRef50_Q1AZD3 CRISPR-associated protein, Cas5h family n=1 Tax=...    91   3e-17
UniRef50_B1I5P1 CRISPR-associated protein Cas5 n=2 Tax=Clostridi...    78   3e-13
UniRef50_D1CHV1 CRISPR-associated protein Cas5 n=1 Tax=Thermobac...    63   9e-09
UniRef50_A5D0Y3 Putative uncharacterized protein n=1 Tax=Pelotom...    59   9e-08
UniRef50_A3DHS3 CRISPR-associated protein Cas5 n=3 Tax=Clostridi...    58   3e-07
UniRef50_D1B1G1 CRISPR-associated protein Cas5 n=1 Tax=Sulfurosp...    58   3e-07
UniRef50_A7ZDW7 Crispr-associated protein Cas5 n=3 Tax=Campyloba...    57   4e-07
UniRef50_A7HLK6 CRISPR-associated protein Cas5, Hmari subtype n=...    57   5e-07
UniRef50_C7P9L3 CRISPR-associated protein Cas5 n=2 Tax=Methanoca...    57   6e-07
UniRef50_D0MJ68 CRISPR-associated protein Cas5 n=1 Tax=Rhodother...    55   2e-06
UniRef50_B7R550 CRISPR-associated protein Cas5 n=1 Tax=Thermococ...    55   3e-06
UniRef50_C9RCY2 CRISPR-associated protein Cas5, Hmari subtype n=...    54   3e-06
UniRef50_B5YBH8 CRISPR-associated protein Cas5, Hmari subtype n=...    53   8e-06
UniRef50_C6QNG6 CRISPR-associated protein Cas5, Hmari subtype n=...    53   8e-06
UniRef50_O27159 Putative uncharacterized protein n=1 Tax=Methano...    53   9e-06
UniRef50_D1A6P6 Metal dependent phosphohydrolase n=1 Tax=Thermom...    52   2e-05
UniRef50_A4J1X9 CRISPR-associated protein Cas5, Hmari subtype n=...    52   2e-05
UniRef50_O57910 Putative uncharacterized protein PH0171 n=1 Tax=...    51   3e-05
UniRef50_Q2NH81 Putative uncharacterized protein n=1 Tax=Methano...    50   4e-05
UniRef50_B1LAM2 CRISPR-associated protein Cas5, Hmari subtype n=...    50   5e-05
UniRef50_D2QT47 CRISPR-associated protein Cas5 n=1 Tax=Spirosoma...    49   1e-04
UniRef50_A3XI99 Putative uncharacterized protein n=1 Tax=Leeuwen...    49   1e-04
UniRef50_C7NNV3 CRISPR-associated protein Cas5, Hmari subtype n=...    48   2e-04
UniRef50_C8PE23 CRISPR-associated protein Cas5 n=1 Tax=Campyloba...    48   2e-04
UniRef50_B9MPU1 CRISPR-associated protein Cas5, Hmari subtype n=...    47   4e-04
UniRef50_B1B9K0 Crispr-associated protein Cas5, tneap subtype n=...    47   4e-04
UniRef50_A3DKB9 CRISPR-associated protein Cas5, Hmari subtype n=...    47   5e-04
UniRef50_C8VZL1 CRISPR-associated protein Cas5 n=1 Tax=Desulfoto...    46   8e-04
UniRef50_B1I4M5 CRISPR-associated protein Cas5 family n=1 Tax=Ca...    46   8e-04
UniRef50_Q3M7D6 Fruiting body developmental protein S-like prote...    46   0.001
UniRef50_C1DUR1 Crispr-associated protein Cas5, hmari subtype n=...    46   0.001
UniRef50_A7BQN4 Protein containing DUF522 n=1 Tax=Beggiatoa sp. ...    46   0.001
UniRef50_B8CYA3 CRISPR-associated protein Cas5 n=1 Tax=Halotherm...    45   0.002
UniRef50_Q8PZD2 Putative uncharacterized protein n=1 Tax=Methano...    45   0.002
UniRef50_A1ZVP9 Crispr-associated protein Cas5, tneap subtype n=...    44   0.003
UniRef50_A8F3P0 CRISPR-associated protein Cas5, Hmari subtype n=...    44   0.004
UniRef50_A4XGC7 CRISPR-associated protein Cas5 family n=1 Tax=Ca...    43   0.008
UniRef50_D1QSA9 CRISPR-associated protein Cas5, Tneap subtype n=...    41   0.026
UniRef50_B9LWL0 CRISPR-associated protein Cas5, Hmari subtype n=...    41   0.041
UniRef50_A1HND7 CRISPR-associated protein Cas5 family n=1 Tax=Th...    40   0.063

>UniRef50_Q46898 Uncharacterized protein ygcI n=13 Tax=Proteobacteria
           RepID=YGCI_ECOLI
          Length = 224

 Score =  278 bits (712), Expect = 7e-74,   Method: Composition-based stats.
 Identities = 224/224 (100%), Positives = 224/224 (100%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES
Sbjct: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL
Sbjct: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180
           WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD
Sbjct: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180

Query: 181 IYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVSQ 224
           IYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVSQ
Sbjct: 181 IYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVSQ 224


>UniRef50_B7KJ26 CRISPR-associated protein Cas5 family n=1 Tax=Cyanothece sp. PCC
           7424 RepID=B7KJ26_CYAP7
          Length = 215

 Score =  223 bits (568), Expect = 4e-57,   Method: Composition-based stats.
 Identities = 67/228 (29%), Positives = 111/228 (48%), Gaps = 17/228 (7%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M   L+LRLAGP+Q+WG+ +    R T   PT+SG++GL+ A +GI RD+   L  L++ 
Sbjct: 1   MMKTLLLRLAGPLQSWGRGSRFDFRDTDTIPTKSGVIGLVAAAMGINRDNQVELAKLAQ- 59

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           ++  V  ++            + DYHTV+G      G      IQ++R+YLC+A F V L
Sbjct: 60  LRMGVCVEK--------EGKLVVDYHTVIGTIH-ADGKPHKAPIQSYRQYLCNAEFLVGL 110

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNY--EPVG 178
             +     +++E+E  +  P++  +LGR++CP + P+F+        + AL  Y    + 
Sbjct: 111 ESS--EYHLLNEIEHYLCFPKWELFLGRKACPPSKPIFVDLLTN-SLEDALYQYAISHLK 167

Query: 179 GDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIK--GGMDVSQ 224
              Y     +         D P+    R F++R     K     DVS+
Sbjct: 168 KGTYRLLIESKEPTGALRLDVPIDFKKRIFSARTVITPKPLEVSDVSE 215


>UniRef50_D1NTI1 CRISPR-associated protein Cas5 n=1 Tax=Bifidobacterium gallicum DSM
           20093 RepID=D1NTI1_9BIFI
          Length = 250

 Score =  220 bits (561), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 66/226 (29%), Positives = 101/226 (44%), Gaps = 28/226 (12%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            S LILRLAGPMQ+WG  +    R T   PT+S ++GLL +  G +R+D  S++ L   +
Sbjct: 1   MSVLILRLAGPMQSWGDSSRFNRRETRTEPTKSAVIGLLASAQGRRRED--SIEDLL-GL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +F VR D+            +RD+ T         G  S     T R YL DA F VA+ 
Sbjct: 58  RFGVRSDQ--------PGRIMRDFQTEKSIARKKSGEFSLTMPLTHRYYLADAKFLVAIE 109

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                  ++  L+ A+  P++  +LGRRSCP   P+ LG    ++ ++AL     +    
Sbjct: 110 ---GERSLLESLDAALRNPQWPLFLGRRSCPPASPVSLGVKDYANVEEALDKEPWIASPW 166

Query: 182 YSE------------ESVTGHHLKFTARDEPMITL--PRQFASREW 213
           Y +            ++V          D P+      R++A R  
Sbjct: 167 YRKKVHDSKRLQVVVDAVENGETTGQQSDMPLSFSQKHRRYAQRPV 212


>UniRef50_D1CGD4 CRISPR-associated protein Cas5 family n=6 Tax=Bacteria
           RepID=D1CGD4_THET1
          Length = 230

 Score =  211 bits (537), Expect = 2e-53,   Method: Composition-based stats.
 Identities = 68/226 (30%), Positives = 106/226 (46%), Gaps = 25/226 (11%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L++RL+GPMQ+WG  +    R TGR P++SG++GL+ A LG  R  T+ +  L   +
Sbjct: 1   MPTLLMRLSGPMQSWGTQSRFTVRDTGREPSKSGVIGLICAALGRPR--TAPVDDLV-RL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHET-----IQTWREYLCDASF 116
           +  VR D             +RDYHT  GA    R   +  T     +Q+ R YL DASF
Sbjct: 58  RMGVRVDR--------EGIVMRDYHTAGGAPAGERYGVATVTGDQRPVQSSRYYLADASF 109

Query: 117 TVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGT-------CQASDPQK 169
            VAL        ++ ++++A+  PR+  +LGR+SC  + P+ L          +  D + 
Sbjct: 110 LVALEGGEEDRPLLEQIDEALRAPRWQLFLGRKSCVPSEPIHLPKEPPLGPPIREEDLRT 169

Query: 170 ALLNYEPVGGDIYSEESVTGHHLKFTARDEPMIT--LPRQFASREW 213
           AL++Y    G             +    D P+      RQ+A+R  
Sbjct: 170 ALISYPWPEGAHRLRFVFEDPEGEELRNDVPISFEIGNRQYAARFV 215


>UniRef50_Q12YA8 CRISPR-associated protein, CT1976-like n=1 Tax=Methanococcoides
           burtonii DSM 6242 RepID=Q12YA8_METBU
          Length = 244

 Score =  209 bits (533), Expect = 5e-53,   Method: Composition-based stats.
 Identities = 63/244 (25%), Positives = 100/244 (40%), Gaps = 38/244 (15%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M+ YLI RL GPM +WG       RPT   P++S + GL+ A LGI+RD+      LS +
Sbjct: 1   MKEYLIFRLYGPMASWGDIAVGQHRPTYDHPSKSAIFGLIAAALGIRRDEEERHLELSNA 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVL-------------GAREDYRGLKSH--ETIQ 105
             +              +   LRDYHT                 R+D   +      T+ 
Sbjct: 61  YSYGTLI--------NSAGKLLRDYHTSQVPSAGTGRNRKTFATRKDELAVPKEELNTVL 112

Query: 106 TWREYLCDASFTVALWLTPH-ATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQA 164
           + R+Y CD  +TV L          +  L  ++ +P +  YLGR+SCPL  P+      A
Sbjct: 113 STRDYYCDGVYTVILSCKTDTPPYSLELLGNSLKEPSFCLYLGRKSCPLALPINPKIVSA 172

Query: 165 SDPQKALLNYEPVGGDIYSEESVTGHHL--------------KFTARDEPMITLPRQFAS 210
           S+ ++AL + +P    +  +  +   +                 +  D+ +     QF+ 
Sbjct: 173 SNIKEALQSVDPGEEGLVKKIEMKSPYRLYWDDPKESMTCEHTISRYDKLLSRKRWQFSK 232

Query: 211 REWY 214
           R  Y
Sbjct: 233 RNEY 236


>UniRef50_Q314I4 CRISPR-associated protein, CT1976 n=1 Tax=Desulfovibrio
           desulfuricans subsp. desulfuricans str. G20
           RepID=Q314I4_DESDG
          Length = 245

 Score =  209 bits (531), Expect = 7e-53,   Method: Composition-based stats.
 Identities = 79/246 (32%), Positives = 108/246 (43%), Gaps = 33/246 (13%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M  YL  ++ GP+QA+G       RPT   PTRS +LG+L A +GI+RD+ + L  L + 
Sbjct: 1   MAQYLTFQIYGPLQAYGTVAVGEIRPTSTMPTRSAVLGILAAAIGIRRDEETRLAELRDG 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGA----------REDYRGLKSHETIQTWREY 110
            + AVR D             + DYHT+             R D   L    TI + REY
Sbjct: 61  YRVAVRED--------APGKVMLDYHTIQTPGARGKRQLHCRRDELLLTEPNTILSRREY 112

Query: 111 LCDASFTVALWLTPHA-TMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQK 169
           L DA FTV LW   H     + E+ +A+  PR+T  LGR+SCP   P        + PQ+
Sbjct: 113 LMDALFTVCLWQANHTVPYSLQEIARALRSPRWTIGLGRKSCPPALPFAPKITDHTTPQE 172

Query: 170 ALLNYE-----------PVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREW---YV 215
           A+  Y            P    +  +        + T RD P+    RQFA R+     V
Sbjct: 173 AVAAYPADKLVSAGLRSPQVMRMLLDTEGPHTDTETTVRDVPLHHGRRQFAERKVRELLV 232

Query: 216 IKGGMD 221
            K   D
Sbjct: 233 RKAATD 238


>UniRef50_C2BET8 CRISPR-associated protein n=2 Tax=Firmicutes RepID=C2BET8_9FIRM
          Length = 244

 Score =  205 bits (522), Expect = 8e-52,   Method: Composition-based stats.
 Identities = 61/223 (27%), Positives = 101/223 (45%), Gaps = 29/223 (13%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
             ++L+L GPMQ+WG  +   TR +  +P++SG++G++ A  G +RD+   +Q L++ + 
Sbjct: 5   KTILLKLTGPMQSWGTSSRFETRTSDYYPSKSGVIGIIAASFGYERDEDEKIQKLND-LD 63

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWL 122
           FAVR D+             +DYH     R+     +   T  T R Y+ DA F VA+  
Sbjct: 64  FAVRVDQ--------EGVLKKDYHIA---RKVKPNGELERTYVTNRYYMEDAVFVVAI-- 110

Query: 123 TPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDIY 182
           +      + E+ + +  P + P++GRRSCPL     LGT +   P +AL N +    D +
Sbjct: 111 SHEDDKWMEEILQGLKYPYFQPFMGRRSCPLPARFILGTNE-EGPIEALENLDWQAADWF 169

Query: 183 SEE--------------SVTGHHLKFTARDEPMITLPRQFASR 211
            ++                   H     R        R+F  R
Sbjct: 170 KKKNKNYRADIYADKDLLPENSHTIRNDRVVSFSQKERKFGPR 212


>UniRef50_A3EQA4 CRISPR-ssociated protein, Cas5 n=3 Tax=Bacteria RepID=A3EQA4_9BACT
          Length = 227

 Score =  205 bits (522), Expect = 8e-52,   Method: Composition-based stats.
 Identities = 60/222 (27%), Positives = 94/222 (42%), Gaps = 22/222 (9%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L++RL  PMQ+WG  +    R TG+ P++SG++GLL A LGI R++   L+ L+  +
Sbjct: 1   MPTLLIRLVSPMQSWGTSSRFDQRDTGKEPSKSGVIGLLAAALGIDRNNWDDLEPLA-GL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
              VR D              RDY T           K H T  T+REYL DA F V   
Sbjct: 60  SMGVRHDR--------PGIPRRDYQTASKII-SADHSKIHPTAVTYREYLADAVFLVGFE 110

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                  ++ ++  A+  P +  +LGR+S   + P+++     + P +  L + P     
Sbjct: 111 SA--EVSLLEKINSALKNPVWPLFLGRKSYVPSEPIWIENGLKNVPLREALEHFPWIACR 168

Query: 182 YSEESVTGHH---------LKFTARDEPM-ITLPRQFASREW 213
              E +                   D+P+     R+F SR  
Sbjct: 169 RRNERLPEKLVITFESEDGTGVLKMDQPLSSFAKRRFGSRFV 210


>UniRef50_B0TDU1 Crispr-associated protein cas5 n=1 Tax=Heliobacterium modesticaldum
           Ice1 RepID=B0TDU1_HELMI
          Length = 230

 Score =  199 bits (507), Expect = 5e-50,   Method: Composition-based stats.
 Identities = 66/229 (28%), Positives = 101/229 (44%), Gaps = 23/229 (10%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
            L LRL GP+Q+WG  +    R +   PT+SG++GLLG  LG  R+D   L++L  +++ 
Sbjct: 5   ILALRLEGPLQSWGSRSRWDYRDSALEPTKSGIIGLLGCALGWSRNDK-RLESLDAALRL 63

Query: 64  AVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSH-----ETIQTWREYLCDASFTV 118
            VR D+          T L D+HTV G      G +        T+ + R YL +ASF  
Sbjct: 64  TVRIDK--------PGTPLIDFHTVQGYLLMAEGKQKKSGNDMYTVVSRRVYLQEASFLA 115

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQAS--DPQKALLNYEP 176
            L     A   + + +KA+  P +  +LGR+SCP   PLF    +    D  +A+ +   
Sbjct: 116 LLTGEQGA---LHQCKKALNDPVWPVFLGRKSCPPARPLFDSFYEGDFRDVLEAMRSIPW 172

Query: 177 ----VGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMD 221
                 G I     +     +   +D   I   R +  R   V    +D
Sbjct: 173 SSAPAAGPIRLRYVMEDEGGREWRQDVLRINGARMYGRRRVSVGWVDLD 221


>UniRef50_B8HWH8 CRISPR-associated protein Cas5 family n=1 Tax=Cyanothece sp. PCC
           7425 RepID=B8HWH8_CYAP4
          Length = 216

 Score =  199 bits (505), Expect = 8e-50,   Method: Composition-based stats.
 Identities = 52/218 (23%), Positives = 90/218 (41%), Gaps = 22/218 (10%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L+LR+  PM +WG  +    R + R PT+S ++GLL A LG  R    ++  L+ ++
Sbjct: 1   MPTLLLRMRAPMMSWGDHSRFTIRDSRREPTKSAVIGLLCAALGRPR--WEAVADLT-AL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +  VR ++  L           DYHTV  + +         T+ + R Y+ DA + V L 
Sbjct: 58  KMGVRINQEGLVQC--------DYHTVQDSIKSS--GSKGNTVISHRYYIADADYLVGLE 107

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
            +      +  L+ A+  P +  Y GR+S   + P+ L         +AL +   +   +
Sbjct: 108 GS--DRHFLESLDSALQSPIWQVYFGRKSFVPSCPVALHVSDQP-LAEALKHRITLSKTM 164

Query: 182 YSEE------SVTGHHLKFTARDEPMITLPRQFASREW 213
             +        +         +D P+    R F SR  
Sbjct: 165 AHKLPNRLRCVLEVPDSLDVRQDVPLDWQKRHFGSRCV 202


>UniRef50_Q04QB7 Putative uncharacterized protein n=2 Tax=Leptospira borgpetersenii
           serovar Hardjo-bovis RepID=Q04QB7_LEPBJ
          Length = 247

 Score =  198 bits (504), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 61/220 (27%), Positives = 93/220 (42%), Gaps = 18/220 (8%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M+ YL+ RL GP+ +WG       RP+  FPT+S ++GL+ A  G  R +   +  L +S
Sbjct: 1   MKDYLVFRLYGPLVSWGNIAVGEYRPSDSFPTKSAIIGLISASFGFDRSEDGKISELVKS 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSH----------ETIQTWREY 110
           V FA +               LRDYHT+       R L +           ETI + R+Y
Sbjct: 61  VFFATKTLN--------PGNLLRDYHTIQSPGNVKRSLLTRKDELLDSEYVETILSSRDY 112

Query: 111 LCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKA 170
             DA + VAL     A   + E+  A+L P +TPYLGR+SC +  P+      +     A
Sbjct: 113 RVDAVYDVALSEKKRAPYSLKEIRNALLSPIHTPYLGRKSCSIALPMCPEILSSDSFPNA 172

Query: 171 LLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFAS 210
              Y  +    Y            +++   ++ L      
Sbjct: 173 FEEYNKILMKKYESSDYKDPLADLSSKSSAILYLWEDPTE 212


>UniRef50_D0Y918 CRISPR-associated protein Cas5 family n=2 Tax=Dehalococcoides
           RepID=D0Y918_9CHLR
          Length = 205

 Score =  198 bits (504), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 64/213 (30%), Positives = 105/213 (49%), Gaps = 19/213 (8%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
            L++RL GPMQ+WG  +    R T   PTRSG++GL+ A +GI RD+     A  + ++ 
Sbjct: 6   TLLMRLEGPMQSWGYRSRFDCRDTALEPTRSGVIGLICAAMGIARDEDI---ARFDGIRM 62

Query: 64  AVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLT 123
            VR D     ++        DYHT L            +T+ ++R+YL DASFTV L  +
Sbjct: 63  GVRVDRDGKVEQ--------DYHTALDVI--KADGSGKDTVVSYRDYLTDASFTVGLESS 112

Query: 124 PHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDIYS 183
                ++ ++ KA++ P++  +LGR++ PLT P      + S+P K     E +     +
Sbjct: 113 --DRNLLEKIAKALVSPQWVLFLGRKAFPLTKPP---IFEFSNPVKPGSLEEHLLCGASA 167

Query: 184 EES-VTGHHLKFTARDEPMITLPRQFASREWYV 215
           +   +     + T  D P+    R+F  R + V
Sbjct: 168 KRVLLESPDGERTQYDWPLCFGERRFKPRRFTV 200


>UniRef50_Q0W584 Putative uncharacterized protein n=1 Tax=uncultured methanogenic
           archaeon RC-I RepID=Q0W584_UNCMA
          Length = 227

 Score =  197 bits (501), Expect = 3e-49,   Method: Composition-based stats.
 Identities = 61/213 (28%), Positives = 90/213 (42%), Gaps = 20/213 (9%)

Query: 10  AGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDE 69
            GPMQ+WG       R TG  PT+SG++GLLG  LG  R D      L   ++  +R + 
Sbjct: 12  EGPMQSWGLKARWDIRDTGDEPTKSGIIGLLGCALGYARKDPRLTDELDSQLRIGIRVE- 70

Query: 70  LILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPHATMV 129
                        RDYHTV G      G     TI ++R+YL DA+F V L        +
Sbjct: 71  -------CPGEIARDYHTVSGELRTAEGKLRETTIVSFRDYLQDAAFLVVLEGPGE---L 120

Query: 130 ISELEKAVLKPRYTPYLGRRSCPLTHPLFLG-TCQASDPQKALLNYEPVGGDIYSEES-- 186
           ++ +  A+  P +  YLGR+SCP T P+F   T   +    AL  +    G + + ++  
Sbjct: 121 LTRISNALKDPVWPIYLGRKSCPPTRPVFETLTTDYASIDDALSRHPWSSGTMEARKAHP 180

Query: 187 ------VTGHHLKFTARDEPMITLPRQFASREW 213
                 V      +   D    +  R +  R  
Sbjct: 181 KELKCIVEDLSGPYQRTDRMTKSPARMYGIRHV 213


>UniRef50_D0WFC8 CRISPR-associated protein Cas5 n=1 Tax=Slackia exigua ATCC 700122
           RepID=D0WFC8_9ACTN
          Length = 267

 Score =  197 bits (500), Expect = 3e-49,   Method: Composition-based stats.
 Identities = 62/246 (25%), Positives = 105/246 (42%), Gaps = 43/246 (17%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+L+LA P+Q+WG  +    R T   P++SG++GLL A LG +R+D  S+  L+ ++
Sbjct: 4   MTVLLLKLAAPLQSWGASSRFTERTTRHEPSKSGVIGLLAAALGRRRED--SVDDLA-AL 60

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLK---SHETIQTWREYLCDASFTV 118
           +FAVR D+          + +RD+ T    + D    +   +     + R+YL DA F  
Sbjct: 61  RFAVRIDQ--------PGSFMRDFQTEHTRKWDSDTRRFVFNESLSLSKRDYLSDAVFVA 112

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVG 178
           AL        +++E  +A+  P +  +LGRRSCP +  ++LG        +AL +     
Sbjct: 113 ALE---GDEDLLAECAEALHHPAFPLFLGRRSCPPSTQVYLGLVDGP-MMEALADIPWQA 168

Query: 179 GDI-----YSEESVTGHHLK------------------FTARDEPMITL--PRQFASREW 213
            +      Y                              T RD P+      R++  R  
Sbjct: 169 TERHWNYAYRFRGDKPKETVELKVVYEATEEQAACTLSETVRDVPLSFSQLKREYGWRTE 228

Query: 214 YVIKGG 219
             I+  
Sbjct: 229 TTIRMA 234


>UniRef50_B4S8P8 CRISPR-associated protein Cas5 family n=8 Tax=Bacteria
           RepID=B4S8P8_PROA2
          Length = 243

 Score =  195 bits (496), Expect = 8e-49,   Method: Composition-based stats.
 Identities = 55/241 (22%), Positives = 88/241 (36%), Gaps = 26/241 (10%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
           YL+L L  P+Q+WG  +  G R T  FPT+SG+LG+L   LG   +    L+ ++   Q 
Sbjct: 5   YLLLWLEAPLQSWGADSRFGRRGTLEFPTKSGVLGMLCCSLGAGGEQKELLEKMAPLKQS 64

Query: 64  AVRCDELILDDR-----RVSVTGLRDYHTVLGAREDYRGLK--------------SHETI 104
           A+         +           LRD+H V    +D    +              +  + 
Sbjct: 65  AISFCRTSKFRQEEIKKLDREPLLRDFHMVGSGYDDKNPWETLLIPKKSDGTTAVNGGSK 124

Query: 105 QTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQA 164
            T+R YL DA F V + +      +      A+  P +  Y GR+ C  T  ++ G    
Sbjct: 125 ITYRYYLQDAVFAVIMEVPSEKLTLF---ADALENPCWDIYFGRKCCAPTDFIYRGCFNT 181

Query: 165 SDP-QKALLNYEPVGGDIYSEESVTGHHLK--FTARDEPMITLPRQ-FASREWYVIKGGM 220
                   L        +     V G H        D P+    ++ +  R   VI    
Sbjct: 182 ESLAIGKALEIAQEKRLMEDFRVVDGEHEGEAIVLNDVPIQFGEQKLYRERRVTVISCAN 241

Query: 221 D 221
           +
Sbjct: 242 E 242


>UniRef50_A1ARH6 CRISPR-associated protein, Cas5e family n=2 Tax=Bacteria
           RepID=A1ARH6_PELPD
          Length = 232

 Score =  194 bits (492), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 59/228 (25%), Positives = 92/228 (40%), Gaps = 28/228 (12%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L+LRL GPMQ+WG  +    R TG+ P++SG++GLL A LGI R++   L+ L+  +
Sbjct: 1   MPTLLLRLVGPMQSWGTTSRFDQRDTGKEPSKSGVVGLLAAALGIDRENWVDLEPLT-CL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVL-----GAREDYRGLKSHETIQTWREYLCDASF 116
              VR D              RDY T          +          + + R YL DA+F
Sbjct: 60  AMGVRHDR--------PGVPKRDYQTAGCASTDTIIKADGTQAKGGGVVSQRFYLADAAF 111

Query: 117 TVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFL--GTCQASDPQKALLNY 174
            V L        ++  +  A+  P +T  LGR+S   +  +++  G   A    + L  Y
Sbjct: 112 LVGLEC--DDNCLLERIHVALHNPFWTLALGRKSYVPSESIWIVDGVRDAP-LLETLKRY 168

Query: 175 EPVGGDIYSEESVT--------GHHLKFTARDEPM-ITLPRQFASREW 213
             +      EE                    D+P+     R+F +R  
Sbjct: 169 PWIASSRSREEPPERLLVSIESDDGAGVLKMDQPLSSFAERRFGARFV 216


>UniRef50_C9M2Y8 CRISPR-associated protein n=1 Tax=Lactobacillus helveticus DSM
           20075 RepID=C9M2Y8_LACHE
          Length = 241

 Score =  193 bits (491), Expect = 4e-48,   Method: Composition-based stats.
 Identities = 51/200 (25%), Positives = 86/200 (43%), Gaps = 16/200 (8%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
                +RL  P+Q++G       R +  +P++S ++G++ A LG +RDD   LQ    ++
Sbjct: 1   MKTATIRLTAPLQSYGNQASFNQRTSDNYPSKSAVIGIIAAALGYRRDDARILQ--LNNL 58

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
            FAVR ++        S   + ++ TV    E  +         T+RE++ DA F VA+ 
Sbjct: 59  LFAVRIEQ--------SGNMMTEFQTV----EYQKSSTKTARKLTYREFIQDAVFMVAIG 106

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                   I ++  A+  P++  YLGRRS P   PL + T    +P + L          
Sbjct: 107 SDND--HEIEKIVSALKHPKFQLYLGRRSNPPAGPLMIETYDEENPLQVLEKLSWQAEPW 164

Query: 182 YSEESVTGHHLKFTARDEPM 201
           Y +       L     D  +
Sbjct: 165 YQKRLRAPKFLTRIIADAEL 184


>UniRef50_Q5YRB6 Putative uncharacterized protein n=1 Tax=Nocardia farcinica
           RepID=Q5YRB6_NOCFA
          Length = 235

 Score =  192 bits (487), Expect = 9e-48,   Method: Composition-based stats.
 Identities = 62/231 (26%), Positives = 98/231 (42%), Gaps = 36/231 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+LRLA P+Q+WG  +    R T ++P++SG+LGL+ A  G +R D   ++   +++
Sbjct: 1   MTVLLLRLAAPLQSWGVASRFARRETQQYPSKSGILGLIAAARGHRRTD--PIEEALQNL 58

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
            F VR D+            +RD+   L   +  +         + R YL DA F  A+ 
Sbjct: 59  AFGVRVDQ--------PGRLIRDFQVALNIDKTKQ------FPLSQRYYLADAVFLAAI- 103

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                  +I  +  A+ +P +  YLGRRSCP+T PL LG  +    + AL   E      
Sbjct: 104 --QGERGLIEGIGNALRRPEFPLYLGRRSCPVTGPLVLGEPRDVTLEHALHETEWQAATW 161

Query: 182 YSE---------------ESVTGHHLKFTARDEPMITLP--RQFASREWYV 215
           Y                        L+   RD P+   P  R++  R    
Sbjct: 162 YRRSQHRRVRLPIYRDLLPGDPVELLREQVRDMPLSFDPVRREYGWRTVVE 212


>UniRef50_D2RB02 CRISPR system CASCADE complex protein CasD n=3 Tax=Actinobacteria
           (class) RepID=D2RB02_GARVA
          Length = 291

 Score =  192 bits (487), Expect = 9e-48,   Method: Composition-based stats.
 Identities = 53/187 (28%), Positives = 86/187 (45%), Gaps = 17/187 (9%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQR--DDTSSLQALSE 59
              L+L+ +GP+Q+WG  +   TR T  +P++S ++G++ A  G +R  D   ++  L++
Sbjct: 1   MKSLLLKFSGPLQSWGTDSHFETRHTDYYPSKSAVIGMIAAAFGYRRSTDCDENIAKLND 60

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
            + FAVR D+            LRDYH               +   T R YL DA F VA
Sbjct: 61  -LDFAVRIDQ--------QGNLLRDYHIAAKY---KANGDFEKNYVTNRYYLEDAIFLVA 108

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGG 179
           +    +   +I ++  A+  P +   LGRRS P T    LG  +     +ALL +E +  
Sbjct: 109 I--GSNNEQLIYDISNALRSPYFQSSLGRRSLPPTADFILGV-EDCGVIQALLTHEWLAN 165

Query: 180 DIYSEES 186
               +  
Sbjct: 166 KWSKKRF 172


>UniRef50_A8SDR7 Putative uncharacterized protein n=1 Tax=Faecalibacterium
           prausnitzii M21/2 RepID=A8SDR7_9FIRM
          Length = 220

 Score =  191 bits (486), Expect = 1e-47,   Method: Composition-based stats.
 Identities = 74/221 (33%), Positives = 108/221 (48%), Gaps = 24/221 (10%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+LRLA P+QAWG  +   TR TGR PT+SG++GLL A LG++RD++ +L  L+  +
Sbjct: 1   MATLLLRLAAPLQAWGADSKFETRKTGREPTKSGVIGLLAAALGLRRDESEALTRLT-GL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +F VR +             L DYHT        +      +  T+R YL DA F   + 
Sbjct: 60  RFGVRVER--------EGQLLVDYHTA-------KTQDEKTSYVTYRHYLQDAVFLAGIE 104

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
            T   T ++ +L++A+L P +  YLGRR CP T PL LG C     Q+ L    P+    
Sbjct: 105 ST--DTALLQQLQQALLHPAFPLYLGRRCCPPTLPLCLGVCPG-SLQEVLQAEPPLCPGR 161

Query: 182 YSE---ESVTGHHLKFTARDEPMITLP--RQFASREWYVIK 217
            S    ++          RD P+   P  RQ+  R    + 
Sbjct: 162 QSRILLDADPLEPGTAPQRDVPVSFDPHHRQYGYRSVRELW 202


>UniRef50_B2GBJ9 Putative uncharacterized protein n=1 Tax=Lactobacillus fermentum
           IFO 3956 RepID=B2GBJ9_LACF3
          Length = 235

 Score =  191 bits (485), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 54/206 (26%), Positives = 81/206 (39%), Gaps = 23/206 (11%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQR--DDTSSLQALSE 59
              L++R+A P+Q++G P     R T R P++S ++G++GA LG +R  DD  SL  L  
Sbjct: 1   MKTLVIRIAAPLQSYGDPASFEKRTTFRAPSKSAVIGMIGAALGFRRESDDYKSLNDLD- 59

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
              FAVR D+            L D+                    + R YL DA F VA
Sbjct: 60  ---FAVRVDQ--------PGEVLSDFQITH-------YSLKKPGKLSHRIYLQDAVFMVA 101

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGG 179
           L     A  ++ E+E A+  P++  Y GRRS P    L +  C        L        
Sbjct: 102 LSSKQDA--LMEEIEYALRHPKFQLYFGRRSNPPAGILKMKMCPDKTAINVLKELPWQAS 159

Query: 180 DIYSEESVTGHHLKFTARDEPMITLP 205
             +  +            D  ++   
Sbjct: 160 VWFQRKYKKDVFNARIYADAKLVPDR 185


>UniRef50_A7BA63 Putative uncharacterized protein n=1 Tax=Actinomyces odontolyticus
           ATCC 17982 RepID=A7BA63_9ACTO
          Length = 242

 Score =  191 bits (485), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 68/245 (27%), Positives = 103/245 (42%), Gaps = 44/245 (17%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M + L+LRLAGPMQ+WG  +    R T  FPT+S L+GLLGA  G +R D   ++ L+E 
Sbjct: 1   MSAVLVLRLAGPMQSWGADSRFTRRSTEAFPTKSALVGLLGAAQGRRRSD--PIEDLAE- 57

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           +  AVR D+            L D+HT                  + R Y  DA+F   +
Sbjct: 58  LSVAVRVDQ--------PGQLLHDFHTAHRG--------DTSMPLSHRFYRADAAFGAFI 101

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180
                   +I  L +A+++P +  YLGRRSCP T PL L   + S    A+     +   
Sbjct: 102 EGPDD---MIDALAQAIVRPVFPLYLGRRSCPPTLPLRLAVREGSAW-DAVRETPWMAST 157

Query: 181 IYSEESVTGHHLKF-------------------TARDEPMITL--PRQFASREWYVIKGG 219
            Y ++    H ++                    T +D P+      R++  R        
Sbjct: 158 YYQKKQRHDHFVRMRVVADLGIIPPEVEKVAQQTLQDMPISFDSENRKYTLRTVEETYID 217

Query: 220 MDVSQ 224
           ++  Q
Sbjct: 218 LENPQ 222


>UniRef50_Q2JWC5 CRISPR-associated protein Cas5, Ecoli subtype n=1 Tax=Synechococcus
           sp. JA-3-3Ab RepID=Q2JWC5_SYNJA
          Length = 207

 Score =  190 bits (483), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 51/217 (23%), Positives = 90/217 (41%), Gaps = 31/217 (14%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L++RL  PM +WG  +    R + R PT+S ++G+L A LG  R     +  L+ ++
Sbjct: 1   MTTLLMRLRAPMMSWGDHSQFDYRDSRREPTKSAVIGILCAALGRPR--WEPVDDLA-AL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +  VR ++             +D+HTV             ET  + R Y+ D  + V L 
Sbjct: 58  KMGVRVNK--------EGILCKDFHTVQ----------IKET-ISNRYYVADGDYLVGLE 98

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                  ++  L++A+ KP +  +LGR+S   + PL +G  +     +AL  +       
Sbjct: 99  ---GDPNLLRTLDQALQKPYWQVFLGRKSFIPSRPLRVGLVEQP-LLEALRQHPYECSRR 154

Query: 182 YSEE-----SVTGHHLKFTARDEPMITLPRQFASREW 213
                     +         +D P+   PR+F  R  
Sbjct: 155 GKRPSQLRFVLEVSESLDVRQDVPLSWQPRRFGCRAV 191


>UniRef50_Q1EQS9 CRISPR-associated protein n=3 Tax=Streptomyces RepID=Q1EQS9_STRKN
          Length = 280

 Score =  190 bits (482), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 70/241 (29%), Positives = 107/241 (44%), Gaps = 39/241 (16%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           L+LRL+GP+Q+WG+ +    R T RFPTRSG++G+L A LG +R     +  L+  +   
Sbjct: 14  LLLRLSGPLQSWGERSHFNERDTARFPTRSGIIGMLAAALGRRRG--EPVDDLA-RLSLT 70

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKS---------HETIQTWREYLCDAS 115
           VR D             LRD HTV G       + +           T+ T R YL DA+
Sbjct: 71  VRTDR--------PGILLRDLHTVGGGLPAKATVTTAEGKKRPGTTGTLLTHRTYLADAA 122

Query: 116 FTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQAS------DPQK 169
           FT+AL  TP    ++ +  +A+  P +  +LGRRSCP   PL LG  + +       P  
Sbjct: 123 FTIALTSTPDDRPLLDQAAQALNTPCWPLFLGRRSCPPEGPLLLGASEDALHHLVHLPLA 182

Query: 170 ALLNYEPVGGDIYSEESV-------------TGHHLKFTARDEPMITLPRQFASREWYVI 216
           A         +  ++  +              G H      D+P+   PR+ + R   + 
Sbjct: 183 AHPGRGQQDTEFLADRPLNRLPYGTATPVGADGTHPSGEVNDQPLSFDPRRRSYRARPLY 242

Query: 217 K 217
           +
Sbjct: 243 R 243


>UniRef50_A5GBK2 CRISPR-associated protein Cas5 family n=2 Tax=Deltaproteobacteria
           RepID=A5GBK2_GEOUR
          Length = 231

 Score =  189 bits (481), Expect = 5e-47,   Method: Composition-based stats.
 Identities = 61/225 (27%), Positives = 98/225 (43%), Gaps = 10/225 (4%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE-- 59
           +S+L LRL GP+Q+WG  +    R TG  PT+S + G+  A LG  R      + L    
Sbjct: 10  KSFLALRLEGPLQSWGFDSQYNRRNTGLMPTKSAIAGMCCAALGFLRGCDKEQEFLVAFG 69

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
           +V+            + + V  L+DYHTV   R    G  +++ + T R+YL DA+F V 
Sbjct: 70  AVRMTAIAIPRNGAKKELPVRRLQDYHTVQNTRR-ASGAINNDCVLTHRQYLTDAAFGVL 128

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGG 179
           L      + ++ ++  A+  P +  +LGR++C  T P+  G  +  D    LL  +    
Sbjct: 129 LE---GDSTLLKQIAAALENPVWGVWLGRKTCIPTAPVLAGLRENRDEALKLLLKDKPLE 185

Query: 180 DIYSEESVT---GHHLKFTARDEPMITLPRQFASREWYVIKGGMD 221
               +E V                  T  R F+ R    ++ G D
Sbjct: 186 SFARQEDVESFADGRDSLPDMPVSFATERRIFSPRRVRTLQ-GTD 229


>UniRef50_UPI0001AF1D4C CRISPR-associated protein, CT1976 n=1 Tax=Streptomyces ghanaensis
           ATCC 14672 RepID=UPI0001AF1D4C
          Length = 244

 Score =  189 bits (480), Expect = 7e-47,   Method: Composition-based stats.
 Identities = 59/240 (24%), Positives = 89/240 (37%), Gaps = 41/240 (17%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L++    PMQ+WG  +   +R T   PT+SG++GLL A LGI RD    +Q L+E +
Sbjct: 1   MATLLMCFDAPMQSWGTRSQFASRDTATEPTKSGVVGLLAAALGIPRDADEEIQNLAE-L 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +  VR D   + +         D+HTV          K+H T  T R YL DA F V + 
Sbjct: 60  RMGVRVDREGVVEA--------DFHTVQNVPNTE--GKNHRTAVTKRFYLADALFLVGVE 109

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPL-FLGT------CQASDPQKALLNY 174
                T ++ +L  A+  PR+  Y GR++     P+   G               AL  +
Sbjct: 110 --SDDTQLLHQLHTALTAPRWPLYFGRKAFVPARPIPSPGLAGEHHPVTGQSLDDALRTH 167

Query: 175 EPVGGD-----------------IYSEESVTGHHL--KFTARDEPMITLP--RQFASREW 213
             +                                       D P+      R +A R  
Sbjct: 168 PWLENQLRIHANRRTTAYAPSPAWLRTIVDADPLALDVELRHDHPLSFTQQDRSYAPRAV 227


>UniRef50_C7MQD6 CRISPR-associated protein Cas5 n=1 Tax=Saccharomonospora viridis
           DSM 43017 RepID=C7MQD6_SACVD
          Length = 236

 Score =  189 bits (479), Expect = 8e-47,   Method: Composition-based stats.
 Identities = 71/219 (32%), Positives = 104/219 (47%), Gaps = 20/219 (9%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+L L GPMQAWG  +    R T  +PTRSG++G++ A LG Q  D  SL  LS  +
Sbjct: 1   MTTLVLHLDGPMQAWGHASQWDHRDTLDYPTRSGVIGMIAAALGKQWGD--SLDDLSP-L 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGARE----DYRGLKSHETIQTWREYLCDASFT 117
           +F +R D             + DYHT  G  E      +G      + + R Y+ DA++T
Sbjct: 58  RFTIRIDR--------PGRRIVDYHTAGGGYEVGIARVKGGNRAHAVLSDRFYMSDAAYT 109

Query: 118 VALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQK-ALLNYEP 176
           VA+        ++  ++ A+  P + P+LGRRSCP   P  LG       +   L   +P
Sbjct: 110 VAIT---GPDTLLYRVDDALRAPVFGPFLGRRSCPPAGPWHLGLHDGDPLRTLPLHRDKP 166

Query: 177 VGGDIYSEESVTGHHLKF-TARDEPMITLPRQFASREWY 214
             GD  + E V+ H     T R +  +T P +F  R  Y
Sbjct: 167 RDGDTVAVEFVSDHETHGPTDRVDTTLTDPHEFGPRRSY 205


>UniRef50_A5UR14 CRISPR-associated protein, Cas5e family n=1 Tax=Roseiflexus sp.
           RS-1 RepID=A5UR14_ROSS1
          Length = 262

 Score =  188 bits (478), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 75/259 (28%), Positives = 102/259 (39%), Gaps = 55/259 (21%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L LRL GP+Q+WG     G R T   PT+SG++GLLG  LG++RDD + L+ LS+++
Sbjct: 1   MNTLFLRLEGPLQSWGLRARWGERDTTDAPTKSGVIGLLGCALGLRRDD-ARLRDLSDNL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKS--------------------- 100
           +  VR D        +    +RDYHT  G R                             
Sbjct: 60  RMGVRVD--------LPGILMRDYHTTGGGRYSTIASTGGPRYHDEPYIGGVLSAEVTKG 111

Query: 101 ------------HETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGR 148
                        ET  + R YL DASF VAL  +P     I EL  A+  P +  +LGR
Sbjct: 112 RIKVKINQKTGEPETDVSERYYLADASFLVALQGSPD---YIGELATAIQSPVWPLFLGR 168

Query: 149 RSCPLTHPLFLGTCQASDPQKALLNY---EPVGGDIYSEESVTGHHLKFT-------ARD 198
           ++C  + P+F GT Q    + AL N      V              L  T         D
Sbjct: 169 KACVPSTPIFAGTGQFDILEDALKNLLLSPRVETAWQRSRPTQLRLLIETGPGAGNRQYD 228

Query: 199 EPMITLPRQFASREWYVIK 217
                  R F +R      
Sbjct: 229 NIGTPSRRVFRARYVRETW 247


>UniRef50_B1VIY0 CRISPR-associated protein n=9 Tax=Actinomycetales
           RepID=B1VIY0_CORU7
          Length = 240

 Score =  186 bits (473), Expect = 4e-46,   Method: Composition-based stats.
 Identities = 61/234 (26%), Positives = 100/234 (42%), Gaps = 33/234 (14%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M   L+L L GPMQ+WG  +    R T   PT+SG++GL+ A  G +R D   ++ L++ 
Sbjct: 1   MAHSLLLLLKGPMQSWGDESRFSVRATATTPTKSGIVGLIAAAQGRRRTD--GVEDLAK- 57

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           ++ AVR D+        S + LRDY T       +            R +L DA+F  A+
Sbjct: 58  LRMAVRVDQ--------SGSLLRDYQTAQ----PWLKNPGANASLVTRYFLSDAAFVAAV 105

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180
                   ++ ++ +A+ +P Y  Y+GRRSCP+   L +G     D + AL  ++     
Sbjct: 106 E--SEDRELLDQMAEALRRPAYPLYMGRRSCPVHPGLVIGVVDG-DAESALRAHDTWHAT 162

Query: 181 IYSEESV-------------TGHHLKFTARDEPMITLP--RQFASREWYVIKGG 219
               +                G       +D P+   P  R++  RE    +  
Sbjct: 163 AVHRKESPKKVSLAIYRDANPGEGGSVPRQDVPVSFSPEHRKYGWREVIRAEDV 216


>UniRef50_B0S4B6 Putative uncharacterized protein n=1 Tax=Finegoldia magna ATCC
           29328 RepID=B0S4B6_FINM2
          Length = 228

 Score =  185 bits (471), Expect = 7e-46,   Method: Composition-based stats.
 Identities = 60/239 (25%), Positives = 107/239 (44%), Gaps = 33/239 (13%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            S ++L+ A P+Q+WG       R T  +PT+S ++GL+ A  G ++ DT S++ L+ S+
Sbjct: 1   MSVILLKFASPLQSWGGLANYEIRNTEYYPTKSAVIGLVAAAFGYKKTDTESIKRLN-SL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTW---REYLCDASFTV 118
            F+VR D+          + +RD+   +     Y     +  +++    + Y+ DA F +
Sbjct: 60  NFSVRIDQ--------KGSLIRDFQIAMEYNPKYMPNDPNYFVKSNLIQKYYIQDAKFLI 111

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVG 178
           AL  +     ++ ++  A+  P Y  +LGR+S P+     +G    ++  + + +YE + 
Sbjct: 112 AL--SSDDETLMEDVYNALESPAYQLFLGRKSNPINADYLIGKFDGNEL-EIIKDYEWLA 168

Query: 179 GDIYSE--------------ESVTGHHLKFTARD--EPMITLPRQFASR--EWYVIKGG 219
              Y +                 TG   K   RD  E      R F+SR    YV K G
Sbjct: 169 SKWYKKSIKKDSVELSIFSDYIDTGSKEKLIRRDLTESFENTKRDFSSRFEYRYVTKVG 227


>UniRef50_Q1R114 CRISPR-associated protein, CT1976 n=1 Tax=Chromohalobacter
           salexigens DSM 3043 RepID=Q1R114_CHRSD
          Length = 260

 Score =  185 bits (470), Expect = 8e-46,   Method: Composition-based stats.
 Identities = 66/184 (35%), Positives = 92/184 (50%), Gaps = 20/184 (10%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M  +L+ RL  PM +WG+      RPT  +P R  +LGL+GA LGI+RDD      L +S
Sbjct: 1   MTGHLVFRLYAPMASWGEAAVGEARPTATYPGRGAILGLIGAALGIRRDDDEGQLRLRQS 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYR------------GLKSHETIQTWR 108
           +  AV+        +R     LRDYHTV       +               +  TI + R
Sbjct: 61  LGIAVK--------QRSPGWLLRDYHTVQVPPSQSKVNYRSRREELSVPKDALNTILSSR 112

Query: 109 EYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQ 168
           +Y CD  + VAL L P A   + EL+ A+ +PR+T YLGR++CPL  PL     +A   +
Sbjct: 113 DYRCDGLWVVALRLMPDAVWTLDELKSALERPRFTLYLGRKACPLAAPLTPAIVEADHWR 172

Query: 169 KALL 172
            AL 
Sbjct: 173 GALD 176


>UniRef50_A6W168 CRISPR-associated protein Cas5 family n=6 Tax=Gammaproteobacteria
           RepID=A6W168_MARMS
          Length = 258

 Score =  185 bits (470), Expect = 1e-45,   Method: Composition-based stats.
 Identities = 78/253 (30%), Positives = 109/253 (43%), Gaps = 43/253 (16%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M+ YL+ RL GPM +WGQP   G R T   PTRS +LGLLGA LGI+RDD   L AL  S
Sbjct: 1   MKDYLVFRLYGPMASWGQPAVGGDRATAIAPTRSAILGLLGAALGIKRDDAQQLDALHSS 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRG-------------LKSHETIQTW 107
           VQ A +        +    + LRDYHT      + +               +   TI + 
Sbjct: 61  VQMATK--------QVTPTSLLRDYHTSQVPSRNNKYVYRTRKNELLDEHKEKLNTILST 112

Query: 108 REYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDP 167
           R+Y CD  + VA+ LT  +   +  L++A++KP Y   LGR+SCPL  PL      +   
Sbjct: 113 RDYRCDGIWIVAVSLTQESLFSLERLKQALIKPVYVLSLGRKSCPLAAPLLPVLLTSVSL 172

Query: 168 QKALL---------NYEPVGGDIYS-------------EESVTGHHLKFTARDEPMITLP 205
           ++AL          +   +                   +E      L     D+P+    
Sbjct: 173 REALDYPFPSIIDNDKPHLDAVWLRPNKLSTYTWEGSVDEFSGETALTTHPWDDPINRDR 232

Query: 206 RQFASREWYVIKG 218
            QF  R  + I  
Sbjct: 233 WQFKQRTMHQITV 245


>UniRef50_Q47PI7 CRISPR-associated protein, Cas5e family n=12 Tax=Actinomycetales
           RepID=Q47PI7_THEFY
          Length = 245

 Score =  184 bits (467), Expect = 2e-45,   Method: Composition-based stats.
 Identities = 69/233 (29%), Positives = 99/233 (42%), Gaps = 36/233 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L L LAGP+QAWG  +    R T   PT+SG+LGLL A  G +R D   L  L+ ++
Sbjct: 1   MKVLTLLLAGPLQAWGAASRFTRRTTEHAPTKSGVLGLLAAAQGRERTDD--LSDLA-AL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +F VR D+          T +RD+ T +                + R YL DA F  A+ 
Sbjct: 58  RFGVRVDQ--------RGTRIRDFQTAIHLD------TGKSMPVSERFYLADAVFVAAVE 103

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                  +I  L +AV  P Y PYLGRRSCP + P+ LG       ++ L   +    + 
Sbjct: 104 ---GEDTLIDTLHQAVQHPVYLPYLGRRSCPPSRPINLGVHSGKPLEQVLAEEKWHAANW 160

Query: 182 YSE--------------ESVTGHHLKFTARDEPMITLP--RQFASREWYVIKG 218
           Y                ++  G     + RD P+   P  R++A R    +  
Sbjct: 161 YQRQLRDLPEVPLDLLVDAPPGDPGADSLRDLPISFDPVHRRYALRGVRTLTV 213


>UniRef50_A8M404 CRISPR-associated protein Cas5 family n=1 Tax=Salinispora arenicola
           CNS-205 RepID=A8M404_SALAI
          Length = 238

 Score =  184 bits (466), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 65/229 (28%), Positives = 96/229 (41%), Gaps = 35/229 (15%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           L+LRLAGP+Q+WG  +    R T   PT+SG++G+L A  G++R D   L  L  S+ F 
Sbjct: 2   LLLRLAGPLQSWGATSRFTHRHTQVTPTKSGVIGMLAAASGLRRTD--PLTELL-SLDFG 58

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTP 124
           VR D+            LRD+                    T R YL DA F VA+    
Sbjct: 59  VRIDQ--------PGQLLRDFQVARTLDG------RDSMPLTNRYYLSDAVFLVAI---G 101

Query: 125 HATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDIYSE 184
               ++  L ++V +P +  YLGRR+CP   P+ LG        +AL ++         E
Sbjct: 102 GDQALLEGLHESVRRPHFPLYLGRRACPPVAPISLGVHPG-TVDEALRDWPWQAAKRLRE 160

Query: 185 E------------SVTGHHLKFTARDEPMITLP--RQFASREWYVIKGG 219
                        +  G  +  T  D+P+   P  RQ+  R     +  
Sbjct: 161 RGELTVPLEVVSDAPPGADVTETLPDQPISFDPAHRQYGWRAVVRTRIV 209


>UniRef50_D1A6Q5 CRISPR-associated protein Cas5 family n=2 Tax=Actinomycetales
           RepID=D1A6Q5_THECD
          Length = 273

 Score =  183 bits (465), Expect = 4e-45,   Method: Composition-based stats.
 Identities = 70/243 (28%), Positives = 102/243 (41%), Gaps = 44/243 (18%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+L L+GP+Q+WG+ +    R T   PTRSGL+G++ A  G +R  T  +  L  ++
Sbjct: 6   TTGLLLHLSGPLQSWGERSRFNQRDTATAPTRSGLIGMIAAAFGRRR--TEPVTDL-RAL 62

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLG---------AREDYRGLKSHETIQTWREYLC 112
           +F VR D           T LRD+HTV G           E  R      T+ + R YL 
Sbjct: 63  RFTVRIDR--------PGTLLRDFHTVGGGMPRDLTVITAEGKRRAADTATVTSDRYYLQ 114

Query: 113 DASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALL 172
           DA+FTVA+        ++    +A+  PR+  YLGRRSCP   PL L T   +DP  AL+
Sbjct: 115 DAAFTVAVTA--DDPALLDRCAQALRAPRWPLYLGRRSCPPNAPLLL-TVLRTDPVTALI 171

Query: 173 NYEP---------------------VGGDIYSEESVTGHHLKFTARDEPMITLPRQFASR 211
           +                              S       + +            R+F +R
Sbjct: 172 DLPLARTAPRDRGDVLVEFRSDTPFESRAWPSAPEDEQVYTEAQDEPVSFQPHHRRFQTR 231

Query: 212 EWY 214
             Y
Sbjct: 232 PIY 234


>UniRef50_C5SD48 CRISPR-associated protein Cas5 family n=1 Tax=Allochromatium
           vinosum DSM 180 RepID=C5SD48_CHRVI
          Length = 227

 Score =  182 bits (463), Expect = 6e-45,   Method: Composition-based stats.
 Identities = 108/225 (48%), Positives = 134/225 (59%), Gaps = 9/225 (4%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M SYLILRL GPMQAWG  TFE  RP+  FPTRSGLLGLLGACLG+ R DT SL AL+ES
Sbjct: 1   MPSYLILRLDGPMQAWGTHTFEDYRPSNPFPTRSGLLGLLGACLGLDRSDTPSLDALAES 60

Query: 61  VQFAVRCDELILDD-----RRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDAS 115
           V F VR D                T L DYHTVL AR+   G  +   IQ+ REYL DA+
Sbjct: 61  VAFTVRLDTGAPRPGVDRLMPKRHTKLSDYHTVLDARKV-DGSTNKFPIQSHREYLFDAA 119

Query: 116 FTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPL--FLGTCQASDPQKALLN 173
           F VA+   P A+  ++ + +++ +PR+TP LGRRSCPL  PL       +A D + AL  
Sbjct: 120 FAVAIGSRPDASFSLARIAESLRQPRFTPVLGRRSCPLGRPLLERPDCIEADDAKAALAQ 179

Query: 174 YEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKG 218
           + P GG IYSE+ +      +  RD P     RQFA+R  Y+ + 
Sbjct: 180 FPPHGGLIYSEDELVSDQPTWI-RDVPRYGRHRQFATRRLYLHRE 223


>UniRef50_C7LYW6 CRISPR-associated protein Cas5 family n=1 Tax=Acidimicrobium
           ferrooxidans DSM 10331 RepID=C7LYW6_ACIFD
          Length = 253

 Score =  182 bits (463), Expect = 6e-45,   Method: Composition-based stats.
 Identities = 74/238 (31%), Positives = 95/238 (39%), Gaps = 41/238 (17%)

Query: 2   RSYLILRLAGPMQAWGQPTF-EGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
            S L LRL GP+QAWG     +  R T RFPT+SG++GLL A LG  R   ++L  L  +
Sbjct: 1   MSVLALRLGGPLQAWGSSQRLDHYRRTERFPTKSGVIGLLAAALGRPRS--AALDDLG-A 57

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHE----------------TI 104
           ++FAVR D             LRD+HT+    +D +     E                T 
Sbjct: 58  LRFAVRIDR--------PGEVLRDFHTLSSLFDDKKRFAPGEGRLPTASGGYRSAATSTQ 109

Query: 105 QTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQA 164
            T R YL DA F   L         + EL+ A+  P +  YLGRRSCP   PL LG    
Sbjct: 110 VTERFYLADACFVAGLE---GDAAQLQELDDALRTPVFPLYLGRRSCPPDKPLRLGVYDG 166

Query: 165 SDPQKALLNYEPVGGD-------IYSEESVTGHHLKFTARDEPMITLP--RQFASREW 213
                 L +      D       I  E  V          D+     P  R +  R  
Sbjct: 167 -GLIDVLASIPWQANDPAQSATSIRCELVVENPAGDVELADQARSFDPLTRSYTRRRV 223


>UniRef50_A1SV73 CRISPR-associated protein, Cas5e family n=2 Tax=Gammaproteobacteria
           RepID=A1SV73_PSYIN
          Length = 217

 Score =  182 bits (463), Expect = 6e-45,   Method: Composition-based stats.
 Identities = 78/214 (36%), Positives = 110/214 (51%), Gaps = 15/214 (7%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              LIL+  G M A+G  TF+  R    FPTRS ++G+LGA +GI R++ + L ALSE +
Sbjct: 1   MKTLILKTEG-MSAYGLQTFDVHRRANHFPTRSAIMGILGAAMGITRENFNELYALSEQL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           + AV+          +S   + DYHTV   R   +G        T+REY CD+  T A+ 
Sbjct: 60  KIAVQV--------NLSGEKMVDYHTVQHFRSP-QGKIQKGVKPTYREYWCDSEHTFAIS 110

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
               A  VI +L  +V  P +T + GR+SCPLT PLF       +P  AL N+    G I
Sbjct: 111 A---AEHVIEKLVNSVKFPEFTLFQGRKSCPLTRPLFEAVTDDDNPANALKNHGEQ-GQI 166

Query: 182 YSEESVTGHHLKFTARDEPMITLPRQFASREWYV 215
           +S+ S          RD  +  +PR++A R  YV
Sbjct: 167 FSDISGDNQLAIVQVRDL-ITAIPRKYAMRTVYV 199


>UniRef50_Q03C60 CRISPR-associated protein n=4 Tax=Lactobacillus RepID=Q03C60_LACC3
          Length = 236

 Score =  180 bits (457), Expect = 3e-44,   Method: Composition-based stats.
 Identities = 59/234 (25%), Positives = 90/234 (38%), Gaps = 37/234 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              + +RL  P+Q++G       R TG +P++S ++G+L A LG QRDD  ++ AL++ +
Sbjct: 1   MKTISIRLTSPLQSYGNEAQFARRTTGDYPSKSAIIGMLAAALGYQRDD-PAINALNDLL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
            FAVR D+            + ++ T           K      T+R+ L DA F VA+ 
Sbjct: 60  -FAVRVDQ--------PGQVMTEFQTAE--------WKPGTRKLTYRDLLQDAVFVVAI- 101

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                   +  L +A+  PR+  YLGRR+      L + T    DP   L          
Sbjct: 102 -GSEDEAWLDRLAEALRHPRFQLYLGRRANVPAGVLKIQTFAGQDPVGVLAQLPWQASRW 160

Query: 182 YSEESVT---------------GHHLKFTARDE--PMITLPRQFASREWYVIKG 218
           Y   S                         RD         RQ++ R   V K 
Sbjct: 161 YQRRSRRQASMSVQLIADAVLLPERRADLVRDAVHSFDQKHRQYSFRPIAVTKV 214


>UniRef50_C8XAY4 CRISPR-associated protein Cas5 family n=2 Tax=Actinomycetales
           RepID=C8XAY4_NAKMY
          Length = 252

 Score =  180 bits (456), Expect = 3e-44,   Method: Composition-based stats.
 Identities = 67/210 (31%), Positives = 92/210 (43%), Gaps = 20/210 (9%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            S L+LRL GPMQ+WG+ +    R T   P++S ++GLL A LG +R D  +++ L+  +
Sbjct: 1   MSVLVLRLTGPMQSWGERSRYARRETAAEPSKSAIVGLLAAALGRRRTD--AIEDLA-GL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
            F VR D+          T LRD+ T                  + R YL DA F  A+ 
Sbjct: 58  IFGVRVDQ--------PGTLLRDFQTARSLDGAR------TMPLSERYYLSDARFLAAVE 103

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                  +I+ L  A+  P +  YLGRRSCP + P+    C  S P  A L  EP     
Sbjct: 104 ---GPESLIAGLAGALRDPTFPLYLGRRSCPPSEPIAQQDCIRSGPLLAALFDEPWHATK 160

Query: 182 YSEESVTGHHLKFTARDEPMITLPRQFASR 211
                V        A D     +P Q A R
Sbjct: 161 SYRRRVADPARLSIAVDAAATEVPAQLAER 190


>UniRef50_A8LYZ7 CRISPR-associated protein Cas5 family n=2 Tax=Actinomycetales
           RepID=A8LYZ7_SALAI
          Length = 257

 Score =  180 bits (456), Expect = 4e-44,   Method: Composition-based stats.
 Identities = 77/243 (31%), Positives = 107/243 (44%), Gaps = 43/243 (17%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+LRLAGPMQ+WG  +    R TG  PTRS ++G++ A  G  R     L  L+  V
Sbjct: 1   MTGLLLRLAGPMQSWGDHSTFSVRDTGTVPTRSAMIGIIAAAQGRHRG--EPLGDLAP-V 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLK---------SHETIQTWREYLC 112
           QF VR D           T + D+HTV G     R +             TI + R YL 
Sbjct: 58  QFTVRVDR--------PGTVMSDFHTVGGGAPPERTVPTAEGKRRTAGAGTIVSRRFYLA 109

Query: 113 DASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKAL- 171
           DA FTVA+        ++ ++  A+  P + PYLGRRSCP+ HP  L +    DP   L 
Sbjct: 110 DAVFTVAVTGPDD---LVGQIHTALNNPVWGPYLGRRSCPVAHPF-LMSGPIPDPVGRLE 165

Query: 172 -----LNYEPVGGDIYSEESV------TGHHLKFTARDEPMITLP-------RQFASREW 213
                    P   +    + V       G   + T  D PM  +P       R++ +R+ 
Sbjct: 166 HLPLNRRRPPGDEETVRVDFVTGAPHGDGSISRMTLNDVPMEPVPGSPDPRRRRYLTRQV 225

Query: 214 YVI 216
           YV 
Sbjct: 226 YVT 228


>UniRef50_Q2RY19 CRISPR-associated protein, Cas5e family n=1 Tax=Rhodospirillum
           rubrum ATCC 11170 RepID=Q2RY19_RHORT
          Length = 261

 Score =  179 bits (454), Expect = 7e-44,   Method: Composition-based stats.
 Identities = 70/216 (32%), Positives = 95/216 (43%), Gaps = 21/216 (9%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
           R +L+ RL GPM AWG       R T   P +S +LGLL A LGI R D ++ +AL   +
Sbjct: 4   RDFLVFRLVGPMAAWGDIAVGERRGTWDVPAKSAILGLLAAGLGIDRADRTAHEALDRGL 63

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVL----------GAREDYRGLKSHETIQTWREYL 111
            FAVR D             LRDYHT              R D        T+ + R Y 
Sbjct: 64  GFAVRQDR--------PGRLLRDYHTAQAPKARKNARWSTRRDELNDDDLNTVLSDRLYR 115

Query: 112 CDASFTVALWLTPH-ATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKA 170
            +A  T A+W         + +L +A+L+PR+TPYLGR++CPL  P      QA     A
Sbjct: 116 TNAIATPAIWRRQGTEGPTLDQLTQALLRPRFTPYLGRKACPLGWPPRPRLLQADGLLAA 175

Query: 171 LLNYEPVGGDIYSE--ESVTGHHLKFTARDEPMITL 204
              Y+    D   +  ++  G     T R  P+   
Sbjct: 176 FDAYDSAEWDAARQFHKAYPGGWPGDTDRPTPVWFE 211


>UniRef50_C7MTB0 CRISPR-associated protein Cas5 n=1 Tax=Saccharomonospora viridis
           DSM 43017 RepID=C7MTB0_SACVD
          Length = 255

 Score =  178 bits (452), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 73/234 (31%), Positives = 104/234 (44%), Gaps = 36/234 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            S L+LRLAGP+Q+WG+ +    R T  FPT SGLLGLL   +G +R    SL+ L+ ++
Sbjct: 1   MSGLLLRLAGPLQSWGERSTFDVRDTAGFPTHSGLLGLLACVMGRRRG--ESLEDLA-AL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLK---------SHETIQTWREYLC 112
            F +R D           T + DY T  GA      +             T+QTWREYL 
Sbjct: 58  TFTIRVDR--------PGTRIIDYQTAGGALPPSMKVPTADGKGRPAGKGTVQTWREYLA 109

Query: 113 DASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALL 172
           DA F VA+      + V+ ++  A+  P + PYLGRRSCP   PL L      DP   L 
Sbjct: 110 DAVFVVAV---QGPSEVLDQVRHALRYPHWQPYLGRRSCPPDQPLLLDV-PVEDPVAELC 165

Query: 173 NYEPVGGDIYSE------------ESVTGHHLKFTARDEPMITLPRQFASREWY 214
              P+   +  +            E   G   +         ++ R ++ R  +
Sbjct: 166 TRVPLARRVGKDEETVPVDFIFPVERRDGVRSEIHDVPVAFTSVDRAYSPRPVW 219


>UniRef50_D2L2X8 CRISPR-associated protein Cas5 family n=1 Tax=Desulfovibrio sp.
           FW1012B RepID=D2L2X8_9DELT
          Length = 266

 Score =  178 bits (452), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 70/249 (28%), Positives = 98/249 (39%), Gaps = 45/249 (18%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M  YLI +L G + A+G       R +   PTRS + GLL ACLGI+R + + L ALS  
Sbjct: 1   MARYLIFQLYGMLAAYGLVAVGEVRLSAGHPTRSAVFGLLAACLGIRRHEEARLAALSGG 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL---------------KSHETIQ 105
              AVR D           T L DYHT+    E  + +               +   T+ 
Sbjct: 61  YALAVRVD--------APGTSLLDYHTIQTPPEKSKRIYRTRADELGGLLGIDEPPYTVL 112

Query: 106 TWREYLCDASFTVALW------LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFL 159
           + R YLCDA FT  L               +  L +A+ +P  TPYLGR+SCP + P   
Sbjct: 113 SRRGYLCDAHFTACLTPAAAPPTDATPPHTLEALAEALRRPVLTPYLGRKSCPPSLPFHP 172

Query: 160 GTCQASDPQKALLNY------------EPVGGDIYSEESVTGHHLKFT----ARDEPMIT 203
              +    + AL +Y                  ++++E         T     RD  +  
Sbjct: 173 RLGEYDSLEAALADYPLEKLAFPAGLKPHDPAVVFADEDEAITPATVTSRPLVRDRTVQH 232

Query: 204 LPRQFASRE 212
             R F  R 
Sbjct: 233 GRRLFEERR 241


>UniRef50_A8ZZ17 CRISPR-associated protein Cas5 family n=1 Tax=Desulfococcus
           oleovorans Hxd3 RepID=A8ZZ17_DESOH
          Length = 259

 Score =  178 bits (452), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 67/259 (25%), Positives = 99/259 (38%), Gaps = 54/259 (20%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             YL+ RL GPM +WG+     TR T  +P RS ++GL+ A LGI+R +T + QAL +  
Sbjct: 1   MGYLLFRLYGPMASWGEIAVGETRHTANYPGRSAIIGLMAAALGIKRSETENQQALDQGC 60

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVL----------GAREDYR--GLKSHETIQTWRE 109
             AV        + R   + LRDYHT              R D    G     TI + RE
Sbjct: 61  LIAV--------EARSHGSLLRDYHTTQVPDSVGGFVYRTRRDELIIGKPRLGTILSSRE 112

Query: 110 YLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGT-CQASDPQ 168
           Y  DA    A+ + P A   +  ++  + +PR   YLGR+SCPL+ P+       + +  
Sbjct: 113 YRQDALAVSAVRVLPGARYELQTIKTHLEQPRLHVYLGRKSCPLSAPMNPQIDKTSRNFH 172

Query: 169 KALLNYEPVGGDIYSEESVTG---------------------------------HHLKFT 195
           +A   Y              G                                       
Sbjct: 173 EAFQAYAHQPLLPVHHSGKEGLSKRDAYWLGLANDRHYYWEGEPSEFSDTIDLSRVQTRI 232

Query: 196 ARDEPMITLPRQFASREWY 214
             D+P+     QF+ R+ +
Sbjct: 233 RHDQPLSRTRWQFSPRQEH 251


>UniRef50_D1CAJ0 CRISPR-associated protein Cas5 family n=1 Tax=Sphaerobacter
           thermophilus DSM 20745 RepID=D1CAJ0_SPHTD
          Length = 245

 Score =  178 bits (451), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 65/245 (26%), Positives = 97/245 (39%), Gaps = 40/245 (16%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            S L+LRL GPMQAWG  +    R TG  P++SG++GLL A LG  R   + +  L+  +
Sbjct: 1   MSTLLLRLTGPMQAWGTQSRFSWRDTGLEPSKSGVIGLLCAALGRPRS--APVDDLA-RL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLG-AREDYRG-------LKSHETIQTWREYLCD 113
           +  VR D           T   D+HT  G  R    G         +     + R YL D
Sbjct: 58  RMGVRVDR--------EGTMHVDFHTAGGWHRRAEAGYGVPDPSGTARRPQISRRFYLAD 109

Query: 114 ASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDP------ 167
           A F V L        ++  L++A+  PR+  +LGR+S     P+ L       P      
Sbjct: 110 ADFLVGLE---GDEELLVLLDRALAAPRWQLFLGRKSFVPAAPVRLPDTPPWGPGLRPEP 166

Query: 168 -QKALLNYEPVGGDIYSEESV-----------TGHHLKFTARDEPMITLPRQFASREWYV 215
            + AL  Y  +G  +    +             G        D P+    R+F++R    
Sbjct: 167 LETALRTYPWLGYQLPHPRADAPDRLRLVLDAEGDDAADIRMDVPISFAERRFSTRAVRT 226

Query: 216 IKGGM 220
           +    
Sbjct: 227 VWIAT 231


>UniRef50_Q2JH27 CRISPR-associated protein, CT1976 n=6 Tax=Actinomycetales
           RepID=Q2JH27_FRASC
          Length = 276

 Score =  176 bits (447), Expect = 4e-43,   Method: Composition-based stats.
 Identities = 72/255 (28%), Positives = 96/255 (37%), Gaps = 52/255 (20%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
           R  L+LRLAGP+Q+WG  +    R T   PT+SG++GLL A  G +R D   ++ L  S+
Sbjct: 7   RHCLVLRLAGPLQSWGSRSMFNRRDTLTEPTKSGIIGLLAAAQGRRRTD--PIEDLL-SL 63

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGARED-------------YRGLKSHETIQTWR 108
              +R D+          T LRDYHTV   R                    +  T  T R
Sbjct: 64  TLGIRTDQ--------PGTLLRDYHTVSDYRGRPLPSAAVSAKGLQKPTSPAKHTHVTER 115

Query: 109 EYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASD-- 166
            YL DA F  AL        V++ L  A+  P +   LGRR+CP THPL L      D  
Sbjct: 116 FYLQDAVFVAALAAP---EPVLTTLADALRTPAFPLALGRRACPPTHPLLLVPDSEPDAA 172

Query: 167 -----PQKALLNYEPVGGDIYSEE----------------SVTGHHLKFTARDEPMITLP 205
                  + L          + +                 +V          D P    P
Sbjct: 173 LWSGSALEVLRQVPWQARPDHRDALARRRPPRLRRIDLPVTVDDPDGDDVRIDLPTTFDP 232

Query: 206 RQ--FASREWYVIKG 218
            Q  F SR  +    
Sbjct: 233 HQRGFTSRRVHQSWV 247


>UniRef50_B3E5U9 CRISPR-associated protein Cas5 family n=2 Tax=Desulfuromonadales
           RepID=B3E5U9_GEOLS
          Length = 271

 Score =  175 bits (445), Expect = 8e-43,   Method: Composition-based stats.
 Identities = 78/249 (31%), Positives = 111/249 (44%), Gaps = 35/249 (14%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             YL+ RL GP+ +WG+     +R +  +P +S LLGL+ A LGI+RD+     AL+   
Sbjct: 1   MKYLLFRLYGPLASWGEIAVGESRHSAVYPGKSALLGLIAAALGIRRDEEQRQAALASGY 60

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGA----------REDY--RGLKSHETIQTWRE 109
           +FAV+           +   LRDYHT              R D    G +   TI + RE
Sbjct: 61  RFAVKV--------ISTGHPLRDYHTAQAPDSVGKFVYRTRRDELVLGKERLGTILSSRE 112

Query: 110 YLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQK 169
           Y CDA   VA+     A   + E+ +A++KPR+  YLGR+SCP+  PL      A     
Sbjct: 113 YRCDAFSLVAVVAEDDAPYSLDEIREALMKPRFHLYLGRKSCPVAAPLNPLVRDAVGFGD 172

Query: 170 ALLNYE-------PVGGDIYSEESVTGHHL-------KFTARDEPMITLPRQFASREWYV 215
           AL +Y                +E V G  L       KF+  DE +    +Q   R ++ 
Sbjct: 173 ALDSYPYGALFVSSWLMKTAQKEIVEGGKLAEVPSLAKFSREDETVFAYNKQPV-RYYWE 231

Query: 216 IKGGMDVSQ 224
              G  VSQ
Sbjct: 232 GDAGDLVSQ 240


>UniRef50_D0MET6 CRISPR-associated protein Cas5 family n=1 Tax=Rhodothermus marinus
           DSM 4252 RepID=D0MET6_RHOM4
          Length = 252

 Score =  172 bits (436), Expect = 7e-42,   Method: Composition-based stats.
 Identities = 59/234 (25%), Positives = 95/234 (40%), Gaps = 27/234 (11%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L+LR   P+ ++G P  +       +P  S + GLL   LG    +T+ L+ L E +
Sbjct: 1   MEILLLRFDAPLMSFGAPIVDQYGFIQPYPALSMMTGLLANALGYTHAETARLERLQERL 60

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTV---LGAREDYRGLKSHETIQTW----------- 107
           ++AVR D             LRD+ TV        D R   +  T++T            
Sbjct: 61  RYAVREDRR--------GQQLRDFQTVDLSQPFLHDERAWTTRGTLETRQGGTASLGIHI 112

Query: 108 --REYLCDASFTVALWL-TPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQA 164
             R+Y  DA +TVAL L  P     +++LE+A+  P    ++GR+ C    PLF+G  +A
Sbjct: 113 RLRDYWADAVYTVALTLDPPDEPPTLADLEQALRFPARPLFIGRKPCLPAAPLFIGRVEA 172

Query: 165 SDPQKALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKG 218
           +D   AL    P+       +              P+  + R+   R     + 
Sbjct: 173 ADLLDALRR-APLDARADRADFYRVWWETGPDDPPPVEGI-RENLRRPVTDRRD 224


>UniRef50_Q1J367 CRISPR-associated protein, CT1976 n=1 Tax=Deinococcus geothermalis
           DSM 11300 RepID=Q1J367_DEIGD
          Length = 232

 Score =  171 bits (433), Expect = 2e-41,   Method: Composition-based stats.
 Identities = 60/229 (26%), Positives = 90/229 (39%), Gaps = 25/229 (10%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+LRL  PMQAWG  +    R T   P++SG+LGL  A LGI R D+    A    +
Sbjct: 1   MATLLLRLVAPMQAWGTRSRFDDRDTEAEPSKSGVLGLCAAALGIDRADSVEHLA---RL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
            F VR D               DYHT         G     T  T R YL DA+F   L 
Sbjct: 58  AFGVRVDR--------EGVAGTDYHTAQL----RPGNPRTRTDVTRRAYLADAAFWAGLE 105

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGG-- 179
                  ++++L+ A+  P +   LGR++ P + P+  G         AL     +    
Sbjct: 106 ---GDAGLLTDLDAALHNPHWPLSLGRKAFPPSLPICAGPPLEVSLWDALRTAPSLRWRD 162

Query: 180 -----DIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVS 223
                 +  +       L+  A       +P    +R  Y+ +  + V+
Sbjct: 163 DDEPYRLVLDREAVPQPLRAAASPSRRQDVPDGPFARRRYLSRDVLTVT 211


>UniRef50_C9M9R7 CRISPR-associated protein Cas5, Ecoli subtype n=1 Tax=Jonquetella
           anthropi E3_33 E1 RepID=C9M9R7_9BACT
          Length = 243

 Score =  170 bits (431), Expect = 3e-41,   Method: Composition-based stats.
 Identities = 58/222 (26%), Positives = 90/222 (40%), Gaps = 19/222 (8%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             +L+LR  GPM ++G    +  RP  RFP  S + GL+   LG    +T  LQAL + +
Sbjct: 1   MDFLVLRFRGPMMSFGDVAVDEQRPIDRFPGVSMVTGLVANALGWDWSETEKLQALQDRL 60

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHT----------VLGAREDYRGLKSHETIQTWREYL 111
             AVR D         +   LR+Y T          V  +    R L    T+Q +  Y 
Sbjct: 61  VLAVREDR--------AGERLREYQTVALPGKSGLFVTHSIPCSRNLDKPMTVQKYLSYW 112

Query: 112 CDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLG-TCQASDPQKA 170
            ++  T  + LT   T  + E+  A+ KP    +LGR++C  T P+F G    A  P++A
Sbjct: 113 ANSLITCFIALTGLGTPTLDEIACALKKPARPLFLGRKTCLPTEPVFRGEIFGAESPEEA 172

Query: 171 LLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASRE 212
           +L    +              +     D   +    +   R 
Sbjct: 173 VLRSCQLDKRPLKFVESPHSCVVEWPYDGRTVVSQSEIFERR 214


>UniRef50_D1Y486 Crispr-associated protein Cas5 n=1 Tax=Pyramidobacter piscolens
           W5455 RepID=D1Y486_9BACT
          Length = 269

 Score =  170 bits (430), Expect = 4e-41,   Method: Composition-based stats.
 Identities = 64/229 (27%), Positives = 93/229 (40%), Gaps = 36/229 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              LILRL GP+ A+G    +  RPT   P  S + GL+   LG    D   LQ L E +
Sbjct: 1   MDALILRLRGPLMAFGDVAVDEIRPTDLLPGLSEMTGLIANALGWTFQDVEKLQRLQERL 60

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYR------------GLKSHETIQTWRE 109
           + A R D         +   LRDY T   + ED              G K   T+Q +R 
Sbjct: 61  RLASREDR--------TGVPLRDYQTARLSSEDSLWRTDGIVAERGGGSKGEFTVQRYRH 112

Query: 110 YLCDASFTVALWLTP-HATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQ 168
           Y  DA+ TV + L P      + E+  A+  P    ++GR  CP + P+           
Sbjct: 113 YRADAAVTVLIALDPADEAPALEEIRDALRHPARPLFIGRIGCPPSQPIC---------- 162

Query: 169 KALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIK 217
                +EP G +I   +S+    +  T R        R+ ASR   +++
Sbjct: 163 -----FEPEGREIIHTDSLKDAIMHITPRAPLGAQTKREPASRNKVLVE 206


>UniRef50_B8IZA7 CRISPR-associated protein Cas5 family n=1 Tax=Desulfovibrio
           desulfuricans subsp. desulfuricans str. ATCC 27774
           RepID=B8IZA7_DESDA
          Length = 249

 Score =  169 bits (429), Expect = 5e-41,   Method: Composition-based stats.
 Identities = 53/214 (24%), Positives = 86/214 (40%), Gaps = 13/214 (6%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE----- 59
           L LRL  PM ++G  +    R T   P++S + G+L A  G+ R        L +     
Sbjct: 8   LALRLQAPMLSFGNESRFNRRCTASLPSKSVVAGMLCAAKGLHRGSVEEQAFLQQVAAIP 67

Query: 60  SVQFAV-RCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV 118
            +  A+ RC      D  ++     D+HTV G R+   G    +   T R YL D+SF V
Sbjct: 68  MLSVAIPRCLSANGKDWLLAAGRTVDFHTVQGTRKAAGG--IKDCHITTRHYLHDSSFAV 125

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTC--QASDPQKALLNYEP 176
            L        V+ +  +A+  P +  ++GR+ C  + P+F G    +A      L     
Sbjct: 126 FL---NGPYRVLEDAARALQNPVWGLWIGRKCCIPSAPVFGGLFSSEAVALNHMLDAPLE 182

Query: 177 VGGDIYSEESVTGHHLKFTARDEPMITLPRQFAS 210
                    S    +     + E  ++  R+FA 
Sbjct: 183 FFTHEREVHSFEDGNDTVPDQAESFLSAARRFAP 216


>UniRef50_B4UE71 CRISPR-associated protein Cas5 family n=2 Tax=Anaeromyxobacter
           RepID=B4UE71_ANASK
          Length = 246

 Score =  169 bits (428), Expect = 6e-41,   Method: Composition-based stats.
 Identities = 56/189 (29%), Positives = 81/189 (42%), Gaps = 6/189 (3%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M   LILR   P+ A+G    +     G FP  S + GL+   LG    D   L+AL   
Sbjct: 1   MLDALILRFDAPLLAFGGVAVDNHGEVGDFPGLSMVAGLIANALGYDHRDCDRLEALQRR 60

Query: 61  VQFAVRCDELILDDRRVSV-----TGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDAS 115
           ++ AVR D                  L    T  GA E   G  S  T   +R Y  DA 
Sbjct: 61  LRIAVRRDRSGQRLVDFQTVALGQPFLERGWTTRGAVEGRDGAFSDGTHIRYRAYWADAV 120

Query: 116 FTVALWLTPHAT-MVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNY 174
           +T+A+ L P A    +  +E+A+ +P    +LGR++C  + P+  G  Q      AL ++
Sbjct: 121 YTLAVTLDPPAESPGLDAVERALREPERPLFLGRKACLPSVPILAGRLQIPSLLAALASF 180

Query: 175 EPVGGDIYS 183
           E V  D + 
Sbjct: 181 ERVSKDRWE 189


>UniRef50_B8GIV3 CRISPR-associated protein Cas5 family n=1 Tax=Methanosphaerula
           palustris E1-9c RepID=B8GIV3_METPE
          Length = 257

 Score =  166 bits (421), Expect = 4e-40,   Method: Composition-based stats.
 Identities = 69/239 (28%), Positives = 94/239 (39%), Gaps = 37/239 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             YL   L G M +WG       RPT   PTRS +LGLL A LGI+RD+   L AL+ + 
Sbjct: 4   PEYLTFSLYGMMASWGDIAVGEYRPTADHPTRSAVLGLLAAALGIRRDEEERLAALTRAY 63

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRG-------------LKSHETIQTWR 108
           + A+R D             LRDYHT        +G              +   TI + R
Sbjct: 64  KVAIRVD--------APGMLLRDYHTTQVPSAAKKGRQYLTRKDELAAPREVLNTILSTR 115

Query: 109 EYLCDASFTVALWLTPHATM-VISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDP 167
           +Y CDA + V +W    A    +  L + +  P +T YLGR+SCPL  P+      A D 
Sbjct: 116 DYRCDAVYRVYIWCRDTAPPYSLKTLAEHLQHPVFTLYLGRKSCPLALPVNPEVKTAPDL 175

Query: 168 QKALLNYEPVGGDIY------SEESVTGHH---------LKFTARDEPMITLPRQFASR 211
             AL     +            + +V  +                DE +     QF  R
Sbjct: 176 LTALSEEREIELRFLGRVPGNRDSNVRAYWDCTEGIQAEGTSVRNDESLNRRRWQFGRR 234


>UniRef50_Q0AA33 CRISPR-associated protein Cas5 family n=2 Tax=Gammaproteobacteria
           RepID=Q0AA33_ALHEH
          Length = 242

 Score =  166 bits (421), Expect = 4e-40,   Method: Composition-based stats.
 Identities = 53/232 (22%), Positives = 78/232 (33%), Gaps = 24/232 (10%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              LILRL  P+ ++G    +   PT RFP RS L G+L   LG    DT +L +L   +
Sbjct: 1   MPCLILRLDAPLMSFGGVLVDQHNPTDRFPGRSMLTGMLANALGWHHQDTEALNSLQARI 60

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTV---------------LGAREDYRGLKSHETIQT 106
            +A R D        V    LRDY TV                       G       Q 
Sbjct: 61  SYAARWD--------VPPEPLRDYQTVDLGQTHLANPGWTTRGAPEHREGGTAKRGIHQR 112

Query: 107 WREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASD 166
            R Y  +   TVA+ + P    V + L  A+  P    ++GR++C    P+ L   ++ D
Sbjct: 113 DRHYWANGVMTVAVTVPPGEPNV-ATLAAALRHPARPLFIGRKACLPAAPVLLRVRESDD 171

Query: 167 PQKALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKG 218
               L +                     T          +       +  + 
Sbjct: 172 AYHVLASEPRDPRAAADTRFFEACWPPGTTAPATESRQRQNRTDDRDWRTQA 223


>UniRef50_B8FDI0 CRISPR-associated protein Cas5 family n=3 Tax=Bacteria
           RepID=B8FDI0_DESAA
          Length = 240

 Score =  166 bits (420), Expect = 5e-40,   Method: Composition-based stats.
 Identities = 68/243 (27%), Positives = 99/243 (40%), Gaps = 33/243 (13%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
            YL++ L  P+Q+WG  +  G R T  FPTRSG+LGLL   LG   +    L  L+   Q
Sbjct: 4   RYLLMWLEAPLQSWGADSKFGRRDTLPFPTRSGVLGLLLCALGASGEQKELLARLAPYGQ 63

Query: 63  FAVRC------DELILDDRRVSVTGLRDYHTVLGAREDYRGLKS--------------HE 102
             + C            ++      LRD+H V  A  D    +                 
Sbjct: 64  TVISCAGGRPGRSGGSPEKIPRQPLLRDFHMVGSAYNDKDPWERLHIPKTNEGKPAVGGG 123

Query: 103 TIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTC 162
              T+R YL DA F V L L P    +  +  +A+  P +  YLGR++C  T  ++ G  
Sbjct: 124 AKLTYRYYLQDARFAVILELPPD---LAEDFAQALQNPVWDIYLGRKNCAPTEFVYQGVF 180

Query: 163 ----QASDPQKALLNYEPVGGDIYSEESVTGHHL--KFTARDEPMITLP-RQFASREWYV 215
                A D   AL+  + +  D      V G H     T  D P+   P +++  R   V
Sbjct: 181 DSQKDAMDRAAALMEEKELMEDF---RVVDGEHPGEPITLNDVPLQFGPMKKYRDRRVTV 237

Query: 216 IKG 218
           I+ 
Sbjct: 238 IRN 240


>UniRef50_Q2FNU0 CRISPR-associated protein, CT1976 n=1 Tax=Methanospirillum hungatei
           JF-1 RepID=Q2FNU0_METHJ
          Length = 225

 Score =  158 bits (401), Expect = 9e-38,   Method: Composition-based stats.
 Identities = 51/214 (23%), Positives = 80/214 (37%), Gaps = 38/214 (17%)

Query: 35  GLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLG---- 90
            +LG++ A LGI+RDD  +   L     F+V   +            ++D+HT+      
Sbjct: 15  AVLGMVAAALGIRRDDEEAQNRLQAGYGFSVMVLQ--------PGIMIQDFHTIQSVHSS 66

Query: 91  ---------AREDYRGLKSHETIQTWREYLCDASFTVALWLTPHA--TMVISELEKAVLK 139
                     R D   L   ETI + REYLCD      +W+         + E+  +   
Sbjct: 67  SLKKMNHVMTRRDEMNLGDSETILSRREYLCDHVSVACVWIRDAESAQFSLEEIAASFRN 126

Query: 140 PRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNY-----------EPVGGDIYSEE--- 185
           P +  YLGR+SCP   P+     QA   + AL+ +            P    +Y E+   
Sbjct: 127 PVFCLYLGRKSCPPALPVHARVIQADSLKSALVQHIEGFDLLNGFRVPDRVSLYFEDGID 186

Query: 186 -SVTGHHLKFTARDEPMITLPRQFASREWYVIKG 218
                  +    RD  +     QF+ R  Y  + 
Sbjct: 187 IGFDDPVMVMKRRDNILSRSRWQFSDRNEYYARI 220


>UniRef50_UPI0001B51C2B CRISPR-associated Cas5 family protein n=1 Tax=Streptomyces
           viridochromogenes DSM 40736 RepID=UPI0001B51C2B
          Length = 278

 Score =  158 bits (399), Expect = 2e-37,   Method: Composition-based stats.
 Identities = 68/276 (24%), Positives = 100/276 (36%), Gaps = 72/276 (26%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M S L+LRLAGP+Q+WG       R T   PT+SG+ GL+ A LG+ R D   L AL++ 
Sbjct: 1   MTSVLLLRLAGPLQSWGALARFDRRDTLNRPTKSGVTGLVAAALGLDRADD--LGALTD- 57

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLG-------------AREDYRGLKSHET---- 103
           ++FAVR D           T +RD+H V                R   +   + ET    
Sbjct: 58  LRFAVRADR--------PGTAVRDFHIVGSGTYPLRPRDLITDHRRAEKAAAALETSTGP 109

Query: 104 --------------------------------------IQTWREYLCDASFTVALWLTPH 125
                                                 + T R YL DA+F  A+     
Sbjct: 110 VFGHLAARSVTKWYGAPKEIAPDPKTGVLLAGNTTRDAMMTTRWYLADAAFVAAVE--HP 167

Query: 126 ATMVISELEKAVLKPRYTPYLGRRSCPL----THPLFLGTCQASDPQKALLNYEPVGGDI 181
              ++  +  AV  P+   +LGR+SCP     +  +  GT +      ALL         
Sbjct: 168 DQNLLHRISHAVEHPKRLLWLGRKSCPPSGTISGGVHPGTAETILTTTALLPNATSPQPW 227

Query: 182 YSEESVTGHHLKFTARDEPMITLPRQFASREWYVIK 217
              E+  G        D+P+   P        +  +
Sbjct: 228 AWIEAAPGTPGAAQRTDQPVTYHPEHRTHTARWETR 263


>UniRef50_Q0BSC7 Putative uncharacterized protein n=1 Tax=Granulibacter bethesdensis
           CGDNIH1 RepID=Q0BSC7_GRABC
          Length = 225

 Score =  157 bits (396), Expect = 4e-37,   Method: Composition-based stats.
 Identities = 60/234 (25%), Positives = 93/234 (39%), Gaps = 41/234 (17%)

Query: 1   MRS--YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRD-DTSSLQAL 57
           M    +L+  LA  + + G+      R +  +PTRS ++GL+GA LGI+RD D S+L  L
Sbjct: 1   MMQQPFLVFGLAASLGSMGELAGHERRGSLIWPTRSAIIGLMGAALGIERDGDFSALDVL 60

Query: 58  SESVQFAVRCDELILDDRRVSVTGLRDYHTVLGARED------------YRGLKSHETIQ 105
           S  V                +   LRDYHT+                          T  
Sbjct: 61  SIDVAI------------FDAGAPLRDYHTIETIPSAAAKNPNSRPEALRDARGRTNTAI 108

Query: 106 TWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQAS 165
           T R+Y     + +A+         +  +  A+L+P +T Y+GR+SCPL  P      +A 
Sbjct: 109 THRDYRTSVFYGIAVRGAG-----LERIVAALLEPHFTLYVGRKSCPLAAPTGAKIVEAV 163

Query: 166 DPQKALLNYEPVGGDIYSEESVT------GHHLKFTARDEPMITLPRQFASREW 213
             + AL   E +   ++ +ESV                D P+      FA+R  
Sbjct: 164 SAEAAL---EHLKAPLWRKESVKAHLLVTDDPEGEVVTDVPLDRSSWHFATRRV 214


>UniRef50_C5V9N1 CRISPR-associated protein Cas5 n=1 Tax=Corynebacterium matruchotii
           ATCC 14266 RepID=C5V9N1_9CORY
          Length = 223

 Score =  155 bits (392), Expect = 9e-37,   Method: Composition-based stats.
 Identities = 57/234 (24%), Positives = 87/234 (37%), Gaps = 41/234 (17%)

Query: 1   MRSYLILRLAGPMQAWGQPTF-EGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE 59
           M   L +RLAGP+Q+W  P        T   PTRSGL+GLL    G  R +         
Sbjct: 1   MTEALYIRLAGPLQSWAGPAITGNFVRTEPRPTRSGLVGLLAGACGYGRGEYPEWLT--- 57

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHT----------------VLGAREDYRGLKSHE- 102
            + F +R D           T + D+HT                 +G R   + L S   
Sbjct: 58  QLHFQIREDNR--------GTLVDDFHTINPRDTEEEFRSRLLLAMGQRPTKKLLNSTPD 109

Query: 103 ----TIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLF 158
               T  T R Y+ D  F V +         +  L + + +P +  YLGR++   + P +
Sbjct: 110 GQGLTAITERTYIADGEFIVQIKAGSREHQEL--LAEKLQQPHFVTYLGRKAFAPSFPFY 167

Query: 159 LGTCQASDPQKALLNYEPVGGDIYSE--ESVTGHHLKFTARDEPMITLPRQFAS 210
           LG    + P   L     VGG+   +           +T    P++    Q+ +
Sbjct: 168 LG----AGPDDTLARIPTVGGEEPKKILRFYALDDYGYTTTTVPVVKDRNQWLT 217


>UniRef50_B4TTX2 CRISPR-associated protein Cas5 n=15 Tax=Enterobacteriaceae
           RepID=B4TTX2_SALSV
          Length = 241

 Score =  153 bits (388), Expect = 3e-36,   Method: Composition-based stats.
 Identities = 66/235 (28%), Positives = 95/235 (40%), Gaps = 33/235 (14%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M+ YL+ +L  P+ +WG+      R +   PTRS LLGLL A LGI+RD+ + L   +  
Sbjct: 1   MKEYLVFQLYAPLASWGEEASGEIRHSATVPTRSALLGLLAAALGIRRDEEARLNNFNRH 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL------------KSHETIQTWR 108
              AV                LRDYHTV   RE+ +                  T+ + R
Sbjct: 61  YHLAVHAL-------ASQDRWLRDYHTVSAPRENKKYRYYTRRDELTLAPDEVGTLISQR 113

Query: 109 EYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQA---S 165
           EY CD  + VA+  TP A   +SEL +A+L P +  YLGR+SCPL  PL           
Sbjct: 114 EYRCDGYWHVAISATPDAPHSLSELREALLTPHFPLYLGRKSCPLALPLAARLMTGTLKE 173

Query: 166 DPQKALLNYEPVGGDIYSEESV----TGHHLKFTA-------RDEPMITLPRQFA 209
               A+          ++             +           ++P+     QF 
Sbjct: 174 VFTHAVEEISAAELSGFTLREGICYWDDPDEESLVWQQKQHSNNQPVSRQRWQFG 228


>UniRef50_A9HLC6 CRISPR-associated protein Cas5 family n=11 Tax=Acetobacteraceae
           RepID=A9HLC6_GLUDA
          Length = 260

 Score =  152 bits (384), Expect = 8e-36,   Method: Composition-based stats.
 Identities = 64/259 (24%), Positives = 90/259 (34%), Gaps = 52/259 (20%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M  +L   +  PM ++G       R     P RS +LGL+ ACLG+ RDD  +  AL+  
Sbjct: 1   MGQFLTFAMVAPMASFGAIAVGERRDGWDRPARSAVLGLMAACLGLTRDDEDAQAALAAD 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLG--AREDYRGLKSHE----------TIQTWR 108
              A+ C              L DYHT     AR ++R     E          TI + R
Sbjct: 61  YGLAILC--------HAPGKLLTDYHTAQAAPARRNWRPATRAEELAASPGDLATILSRR 112

Query: 109 EYLCDASFTVALWLTPH-ATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDP 167
           +Y        A+W +   A   +  L+ A+ +P +TP LGRRSCP   PL          
Sbjct: 113 DYRMGTWHLGAVWTSGKTARWSLEALQAAMREPVFTPSLGRRSCPAGLPLAPSVTDGVSA 172

Query: 168 QKALLNYEPVGGDIYSEESVTG-------------------------------HHLKFTA 196
              LL+    G +                                           +   
Sbjct: 173 AAVLLDRHRNGPEAGLRIRHDSFRRQFAGASRSGGLLLVLDAVDMAEHGGGHTPLRREIR 232

Query: 197 RDEPMITLPRQFASREWYV 215
           RD+P+     QF  RE  V
Sbjct: 233 RDQPLSRRRWQFGLREEAV 251


>UniRef50_B6B783 CRISPR-associated protein Cas5, Ecoli subtype n=1
           Tax=Rhodobacterales bacterium Y4I RepID=B6B783_9RHOB
          Length = 232

 Score =  150 bits (378), Expect = 4e-35,   Method: Composition-based stats.
 Identities = 63/237 (26%), Positives = 87/237 (36%), Gaps = 39/237 (16%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRD-DTSSLQALSE 59
           M  YLI +L   + A G+      R +   P RS ++G LGA +G++RD D S L AL  
Sbjct: 1   MPEYLIFQLVAAIGAMGEFGGHDRRGSLTLPGRSAVIGTLGAAMGLRRDADFSGLDALGV 60

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGARED------------YRGLKSHETIQTW 107
           +V                     RDYHTV                      +   T  T 
Sbjct: 61  AVA------------SFGKTAPFRDYHTVQTVPSAAVKRPQSRPQALRDAGRKVNTTLTS 108

Query: 108 REYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDP 167
           R+Y  D  F VA+W        ++EL  A+  P +  +LGR+SCPL+ P       A+ P
Sbjct: 109 RDYRADCVFGVAIWGEG-----LAELASALSAPVFQTFLGRKSCPLSAPFDPQIVAAATP 163

Query: 168 QKAL--LNYEPVGGDIYSEESVTGHHLKF-------TARDEPMITLPRQFASREWYV 215
             AL  L   P  G    +  V              T  D  +      F    + V
Sbjct: 164 SAALSQLRLPPWIGAREMDMIVADEGTDLGAPSILETRHDRALDRTLWHFGKGRYAV 220


>UniRef50_B5GY62 Crispr-associated protein (Fragment) n=1 Tax=Streptomyces
           clavuligerus ATCC 27064 RepID=B5GY62_STRCL
          Length = 260

 Score =  145 bits (367), Expect = 7e-34,   Method: Composition-based stats.
 Identities = 60/186 (32%), Positives = 83/186 (44%), Gaps = 28/186 (15%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
            L+LRLAGP+Q+WG  +   +R TG  PT+SG++GLL A     R   + ++ L  +++ 
Sbjct: 85  VLLLRLAGPLQSWGSASAFNSRQTGAEPTKSGVIGLLAAA--DGRARGACIEDL-RALRL 141

Query: 64  AVRCDELILDDRRVSVTGLRDYHTVLGARED-------------YRGLKSHETIQTWREY 110
            VR D         S T LRDYHT    R                    +  T  T R Y
Sbjct: 142 GVRVDR--------SGTLLRDYHTASDHRGRPLAQAGVGAKGTQRPTSPAKYTQVTTRYY 193

Query: 111 LCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKA 170
           L DA F  AL        ++  L++AV  P +   LGRRSC  + PL LG        + 
Sbjct: 194 LQDAVFLAALA---GPRALLDRLDRAVRAPAFPLALGRRSCVPSLPLALGVHPG-SLGEV 249

Query: 171 LLNYEP 176
           L  +  
Sbjct: 250 LSTHPW 255


>UniRef50_C2KP44 Putative uncharacterized protein n=1 Tax=Mobiluncus mulieris ATCC
           35243 RepID=C2KP44_9ACTO
          Length = 245

 Score =  145 bits (367), Expect = 8e-34,   Method: Composition-based stats.
 Identities = 53/183 (28%), Positives = 75/183 (40%), Gaps = 22/183 (12%)

Query: 2   RSYLILRLAGPMQAW-GQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
            + + +RLAGP+Q+W G         T  +PTR  L GL+ ACLG  R          + 
Sbjct: 1   MTSVYIRLAGPLQSWAGAKVSGNISHTQDYPTRGSLEGLVAACLGCPRGKYPLW---FQD 57

Query: 61  VQFAVRCDELILDDRRVSVTGLRD--YHTVL-------GAREDYRGLK-----SHETIQT 106
           +QFAVR D            G+RD              G R   RGL        +T   
Sbjct: 58  LQFAVRVDSPGRICDDYQTIGVRDEDMQVATRLLTLLTGKRATNRGLAFIPDAQGKTTIV 117

Query: 107 WREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASD 166
            R  L DA F V +    H    + +L++A+  P +  YLGR++     P +LG  + S 
Sbjct: 118 RRTLLADAEFIVQIQCEGH----LEQLDQAISDPTFVSYLGRKAFAPGFPFYLGIGEDSA 173

Query: 167 PQK 169
              
Sbjct: 174 IDT 176


>UniRef50_B8IMR2 CRISPR-associated protein Cas5 family n=1 Tax=Methylobacterium
           nodulans ORS 2060 RepID=B8IMR2_METNO
          Length = 273

 Score =  142 bits (359), Expect = 6e-33,   Method: Composition-based stats.
 Identities = 51/187 (27%), Positives = 70/187 (37%), Gaps = 23/187 (12%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M + L+  L  P    G       R +   P RS +LGL+   LGI R D +   AL   
Sbjct: 1   MPAGLVFTLYAPFAGMGDVAVGEERGSFDRPARSAVLGLVAGALGIDRADEAGHAALDRG 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGA----------REDYRGLKSHETIQTWREY 110
            + A+R         R     + DYHTV             R +   +    T+ + R Y
Sbjct: 61  YRLALRL--------RTPGCLVEDYHTVQAPPVDRKARWATRREALAVAGLNTLVSRRAY 112

Query: 111 LCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFL----GTCQASD 166
             D    V L +          L  A+ +P + PYLGR+SCPL  PL      G  +   
Sbjct: 113 RADPIVDVVL-IHVDEGPTPEALATALRRPTFAPYLGRKSCPLGLPLRPLWAEGVTRVGS 171

Query: 167 PQKALLN 173
              AL  
Sbjct: 172 LLAALDE 178


>UniRef50_Q2RXJ5 CRISPR-associated protein, Cas5e family n=5 Tax=Proteobacteria
           RepID=Q2RXJ5_RHORT
          Length = 249

 Score =  142 bits (358), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 51/210 (24%), Positives = 81/210 (38%), Gaps = 8/210 (3%)

Query: 1   MRSY--LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALS 58
           M  +  LI+ L  P+ A+G    +    T  FP  S L GL    LG +R +    Q L 
Sbjct: 1   MPEHRWLIVHLEAPLLAFGGVAIDNVGVTRDFPAASMLTGLFANALGWRRTEWERHQRLQ 60

Query: 59  ESVQFAVRCDELIL-----DDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCD 113
           + + FA R +         D +   ++      T  G  E   G       +  R+Y  D
Sbjct: 61  DRLIFAARRERENPTGVLTDTQNAKLSKTERGWTTWGEPEGRDGASYGAPHRRRRDYHGD 120

Query: 114 ASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFL-GTCQASDPQKALL 172
           AS  VAL L       + +L  A+ +P    ++GR+SC  + PL       A+   +AL 
Sbjct: 121 ASVVVALRLDAAEEPALDDLAAALDRPARPLFIGRKSCVPSRPLRGKEFVVAATAYQALQ 180

Query: 173 NYEPVGGDIYSEESVTGHHLKFTARDEPMI 202
                G D   + +       +   + P+ 
Sbjct: 181 ALRSDGNDRQRDGAAAERRAVWPVGEGPVD 210


>UniRef50_Q6NEQ9 Putative uncharacterized protein n=1 Tax=Corynebacterium
           diphtheriae RepID=Q6NEQ9_CORDI
          Length = 242

 Score =  138 bits (349), Expect = 1e-31,   Method: Composition-based stats.
 Identities = 49/184 (26%), Positives = 75/184 (40%), Gaps = 22/184 (11%)

Query: 1   MRSYLILRLAGPMQAW-GQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE 59
           M     +RL+GP+Q+W G         T   PT S L GLL   LG +R +  +      
Sbjct: 1   MIESAYIRLSGPLQSWAGSVVTGNIVRTEPRPTFSSLRGLLAGALGARRGEWPNWLD--- 57

Query: 60  SVQFAVRCDE-LILDDRRVSVTGLRDYHTVLGAREDYRGLKSH-------------ETIQ 105
            V+F VR D   I+ +   ++  L +  T        +G K++              T  
Sbjct: 58  DVEFWVREDRKPIVVNEFQTINPLPEVETFRKRLLIAQGRKANSAKALTFTPDAQGGTSI 117

Query: 106 TWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQAS 165
             R YL D  + V +  + H    + E+E A   P +  YLGR++     P +LG   A 
Sbjct: 118 VNRTYLADGEYLVRVTSSTH----MDEIENAFSSPAFVTYLGRKAFYAEFPFYLGRGSAD 173

Query: 166 DPQK 169
             +K
Sbjct: 174 AFEK 177


>UniRef50_B5F422 CRISPR-associated protein Cas5 n=59 Tax=Enterobacteriaceae
           RepID=B5F422_SALA4
          Length = 248

 Score =  136 bits (342), Expect = 6e-31,   Method: Composition-based stats.
 Identities = 69/255 (27%), Positives = 101/255 (39%), Gaps = 39/255 (15%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M  YL+ +L GPM +WG       R +   P+RS LLGLL A LGI+RD+   L A +  
Sbjct: 1   MSQYLVFQLHGPMASWGVDAPGEVRHSHELPSRSALLGLLAAALGIRRDEEERLNAFNRH 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL-----------KSHETIQTWRE 109
            QF        L     +    RDYHTV   +E  +             +    + + R+
Sbjct: 61  YQF--------LLCASGNPRWARDYHTVQMPKEVRKARYFSRREELQDPELLSALISRRD 112

Query: 110 YLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQK 169
           Y  DA + +A+  TP A   +++L+ A+  P +  YLGR+S PL  PL     + S    
Sbjct: 113 YYTDAWWMIAVSATPDAPYTLAQLQAALQHPVFPLYLGRKSHPLALPLAPQLLEGSAADV 172

Query: 170 ALLNYEPVGGDIYSEESV----------TGHHLKFT------ARDEPMITLPRQFASREW 213
               Y        + +             G H   T       RD P+      F  R  
Sbjct: 173 LREAYRWYQDQFNALKLPLPRLQNECWWEGEHDGLTASKILRRRDMPLSRQQWLFGERSV 232

Query: 214 ----YVIKGGMDVSQ 224
               ++ K    +SQ
Sbjct: 233 NQGPWLRKEDACISQ 247


>UniRef50_B6XT64 Putative uncharacterized protein n=2 Tax=Bifidobacterium
           RepID=B6XT64_9BIFI
          Length = 212

 Score =  136 bits (342), Expect = 7e-31,   Method: Composition-based stats.
 Identities = 49/196 (25%), Positives = 76/196 (38%), Gaps = 28/196 (14%)

Query: 39  LLGACLGIQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL 98
           +L +  G  R+D   ++ L   + F VR ++            +RD  T           
Sbjct: 1   MLASAQGRTRED--PIEDLL-GISFGVRVEQR--------GRVIRDLQTEKSLTRKRNSR 49

Query: 99  K-SHETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPL 157
           K   E   T+R YL DA F VAL        V+  L++A+  P++  YLGRRSCP  +PL
Sbjct: 50  KFDKEMPLTYRYYLADACFLVAL---GADRSVLEMLDEAIHSPKWPLYLGRRSCPPNYPL 106

Query: 158 FLGTCQA-SDPQKALLNYEPVGGDIYSEE----------SVTGHHLKFTARDEPMITLP- 205
            LG      D ++AL +      + Y                      T  D P+     
Sbjct: 107 SLGIHDEYEDIRQALNSETWHASEWYRRRYRYPDLEIVCDAEKGENITTQSDLPLSFSRE 166

Query: 206 -RQFASREWYVIKGGM 220
            R++A+R  +  +   
Sbjct: 167 GRRYANRAVHRYRIPN 182


>UniRef50_B6IWM3 CRISPR-associated protein, CT1976 family n=1 Tax=Rhodospirillum
           centenum SW RepID=B6IWM3_RHOCS
          Length = 280

 Score =  135 bits (340), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 57/208 (27%), Positives = 84/208 (40%), Gaps = 31/208 (14%)

Query: 3   SYLILRLAGPMQAWGQPTFEG----TRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALS 58
           ++L   LA P  AWG  +        + T   P+RS L GLLGA LG++R   + L  LS
Sbjct: 6   AHLCFTLAAPYGAWGAASQSSATTAWKATELDPSRSALTGLLGAALGLER---AHLGRLS 62

Query: 59  ESVQFAVRCDELILDDRRVSVTGLRDYHTVLGA---------------REDYRGLKSHET 103
           E+++FAVR       D +       DYHT+  A               R    G K    
Sbjct: 63  EALRFAVRTGIRPTRDPQP------DYHTISRAHRPEGREHWSRFEELRPALAGGKQEGA 116

Query: 104 IQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQ 163
           + + REY     +TVA+     A + +  L +A+  P +  Y GR++C L  P       
Sbjct: 117 LLSRREYWSLGLWTVAVATLNPAGVPLDRLAQALRTPHWPLYAGRKACTLGLPPDPEVRT 176

Query: 164 ASDPQKALLNYEPVGGDIYSEESVTGHH 191
              P   LL+Y         +  +    
Sbjct: 177 GPGPLSVLLDYGW---PWQRKPGLDRPL 201


>UniRef50_C2GEY8 CRISPR-associated protein n=1 Tax=Corynebacterium glucuronolyticum
           ATCC 51866 RepID=C2GEY8_9CORY
          Length = 242

 Score =  134 bits (337), Expect = 2e-30,   Method: Composition-based stats.
 Identities = 48/189 (25%), Positives = 75/189 (39%), Gaps = 37/189 (19%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTR-PTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE 59
           M S   +RL+GP+Q+W   +  G    T   PT +GL GLL   LG +RD+         
Sbjct: 1   MPSSTFIRLSGPIQSWAGQSVSGNFIRTNPIPTLTGLRGLLAGALGARRDEIPEW---IS 57

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKS------------------- 100
            V+F+VR D+        + + + D+ T+    E++   +                    
Sbjct: 58  KVRFSVREDQ--------TGSFVDDFQTIGSREEEWDFRRRIAILQGMKARSIKQLSFKP 109

Query: 101 --HETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLF 158
                    R YL +A F V +    H      E++ A   P +  YLGR++ P   P +
Sbjct: 110 AVGANAVVRRTYLSEAEFIVRVTDERHT----EEIDHAFSSPVFATYLGRKAFPAAFPFY 165

Query: 159 LGTCQASDP 167
           LGT      
Sbjct: 166 LGTGNEDVL 174


>UniRef50_C0W6U0 CRISPR-associated Cas5 family protein n=1 Tax=Actinomyces
           urogenitalis DSM 15434 RepID=C0W6U0_9ACTO
          Length = 201

 Score =  133 bits (334), Expect = 5e-30,   Method: Composition-based stats.
 Identities = 50/193 (25%), Positives = 75/193 (38%), Gaps = 39/193 (20%)

Query: 39  LLGACLGIQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL 98
           +L A +G +R D   ++ L  S++F VR D+          T LRD+HT           
Sbjct: 1   MLAAAVGRRRTD--PIEDLL-SLRFGVRKDQ--------PGTVLRDFHTARTLDGKQ--- 46

Query: 99  KSHETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLF 158
                  + R YL DA +  A+        ++  L+ AV  P +  YLGRRSCP + PL 
Sbjct: 47  ---SMPLSERYYLADAVYLAAIE---GEKTLLEGLDVAVRHPVFPLYLGRRSCPPSQPLS 100

Query: 159 LGTCQASDPQKALLNYEPVGGDIYSEESV----------------TGHHLKFTARDEPMI 202
           LG   A    +AL +      D +                           +T  D P+ 
Sbjct: 101 LGIRHA-SLLQALTDEPWQAADWFRLRQDNSFRAEIVIDAASLAPDERGSGYTTLDSPVS 159

Query: 203 TLPRQ--FASREW 213
             PR+  + +RE 
Sbjct: 160 FDPRRRDYQAREV 172


>UniRef50_B8IJS9 CRISPR-associated protein Cas5 family n=1 Tax=Methylobacterium
           nodulans ORS 2060 RepID=B8IJS9_METNO
          Length = 253

 Score =  129 bits (325), Expect = 5e-29,   Method: Composition-based stats.
 Identities = 51/244 (20%), Positives = 81/244 (33%), Gaps = 34/244 (13%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           MR +L+L L  P+QAWG    +   P   FP  + + GL+   LG  R D   L+AL E 
Sbjct: 1   MREHLLLLLEAPLQAWGGVLVDAYGPVDEFPAATLVGGLVANALGYDRADWQRLEALQER 60

Query: 61  VQFAVRCDELI---LDDRRVSVTGLRDYHTVLGAREDYRGLKS--HETIQTWREYLCDAS 115
           +              D++   +       T  G  E   G         + +R+Y  D  
Sbjct: 61  LVVGAAVLRRGSTITDNQNAKLEKGDVGWTTRGRPEGRGGGAEAYKSPHRRFRDYHADTL 120

Query: 116 FTVALWLTPHAT-MVISELEKAVLKPRYTPYLGRRSCPLTH-PLFLGTCQASDPQKAL-- 171
             VAL L P      +  +   +  P    +LGR+ C  +   ++    +A    KAL  
Sbjct: 121 ALVALRLDPEDEKPDLDAIAHTLEWPERPLFLGRKPCLPSRSIVWPERMRAETLLKALNL 180

Query: 172 -------------------------LNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPR 206
                                      +    G+  S   V     +    D P+    R
Sbjct: 181 GAAMLVAAESANPKLRLELDAGPWRARWPEREGNAPSSRLVEVCDDRDFRNDVPVGLRRR 240

Query: 207 QFAS 210
           +  +
Sbjct: 241 RVGT 244


>UniRef50_Q3AA65 CRISPR-associated protein Cas5, Hmari subtype n=1
           Tax=Carboxydothermus hydrogenoformans Z-2901
           RepID=Q3AA65_CARHZ
          Length = 248

 Score =  118 bits (296), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 45/235 (19%), Positives = 78/235 (33%), Gaps = 33/235 (14%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGR------FPTRSGLLGLLGACLGIQRDDTSSL 54
           MR  ++  + GP              T        FP R+ L G++ A LG+ +D   SL
Sbjct: 1   MRKVIVFEIRGP------AAHFRKFYTNSSSLSYAFPARTTLAGIIAAVLGLPKDSYYSL 54

Query: 55  ---QALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAR--EDYRGLKSHETIQTWRE 109
                   +++      +++   + V    L++ +   G         L        +R 
Sbjct: 55  LTGNKAHYALRLMTPVRKIMQTVKFVRTKTLKEVNGSGGPTMIPTEIILPVRGRELIYRV 114

Query: 110 YLCDASFTVALWLTPHATMVISELEKAV-LKPRYTPYLGRRSCPLTHPL---FLGTCQAS 165
           Y                     EL K + L P++  YLGR            F GT   +
Sbjct: 115 Y-----------FYHDDPSFQEELAKQLALGPKFPVYLGRSEFLAKIDFLGVFPGTALET 163

Query: 166 DPQKALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLP-RQFASREWYVIKGG 219
           +    ++N E +  +     ++ G  L++     P    P R  AS    V + G
Sbjct: 164 NFVDTVVNLELLKDEELLFSTLHGEDLRYLKEKMPFSFNPDRSIASTASVVYEIG 218


>UniRef50_D1N0K0 Putative uncharacterized protein n=1 Tax=Victivallis vadensis ATCC
           BAA-548 RepID=D1N0K0_9BACT
          Length = 239

 Score =  115 bits (287), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 39/242 (16%), Positives = 69/242 (28%), Gaps = 36/242 (14%)

Query: 2   RSYLILRLAGPMQAWGQP--TFEGTRPTGRFPTRSGLLGLLGACLGI--QRDDTSSLQAL 57
            S LI  LAG M  W     +       G  P    L G++GA LG    R   +     
Sbjct: 1   MSILIFELAGEMAMWRNVYESMGSYSCLGPAPGN--LAGVIGAALGFASPRSQAAEKPDA 58

Query: 58  SESVQFAVRCDELILDDRRVSVTGLRDYHTV---LGAREDYRGLKSHETIQTWR------ 108
            +   +        +    ++     D+H     +G          +   +  R      
Sbjct: 59  KQLKNWDKAGLPWPVSPELLAWEETNDFHVACRWIGKFPKRVPWNINGCKEINRSDNLRL 118

Query: 109 --EYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSC------------PLT 154
             + + D ++ VA+ L  +       +  A+ KP +   LG   C               
Sbjct: 119 QQQVILDPAYEVAVALPAYEA---ERVAAALRKPAFPLCLGASFCRAIVRNVRIEDAVPE 175

Query: 155 HPLFLGTCQASDPQKALLNYEPV--GGDIYSEESVTGHHLKFTARDEPMITLPRQFASRE 212
            P +          +A      +   G  +      G+ +  T     +I    +   R 
Sbjct: 176 SPFWAFRTDGGALGEATPFSRHIVNPGSCFERIRSDGYWIYPTPDQPGVIAA--EPLVRG 233

Query: 213 WY 214
           W 
Sbjct: 234 WV 235


>UniRef50_A0LM54 Putative uncharacterized protein n=1 Tax=Syntrophobacter
           fumaroxidans MPOB RepID=A0LM54_SYNFM
          Length = 210

 Score =  103 bits (257), Expect = 5e-21,   Method: Composition-based stats.
 Identities = 38/196 (19%), Positives = 72/196 (36%), Gaps = 39/196 (19%)

Query: 46  IQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQ 105
           ++R D +       +++  VR D              +D+ T         G  S   + 
Sbjct: 26  LRRGDLA-------ALRMGVRVDR--------EGLLRKDFQTAQNVIVA--GGGSVGDLV 68

Query: 106 TWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFL--GTCQ 163
           + R +L DA+F V L       M++  L  ++  PR+  +LGR+S   + P ++  G  +
Sbjct: 69  SNRYFLSDAAFLVGLE---GDFMLLHRLHASLAHPRWPVFLGRKSYVPSIPPYIKNGLLE 125

Query: 164 ASDPQKALLNYEPV---GGDIYSEESVTGHH--------------LKFTARDEPMITLPR 206
            ++   AL ++ P+          + V                       RD+PM     
Sbjct: 126 GAELMSALASFTPLISVEELAARRKRVESGRRVERTRFVLESASPTHEIRRDQPMSFALG 185

Query: 207 QFASREWYVIKGGMDV 222
           Q    + +V+   +DV
Sbjct: 186 QRVFHDRFVVTEYLDV 201


>UniRef50_UPI0000F51765 hypothetical protein Faci_00030 n=1 Tax=Ferroplasma acidarmanus
           fer1 RepID=UPI0000F51765
          Length = 237

 Score =  103 bits (257), Expect = 5e-21,   Method: Composition-based stats.
 Identities = 21/149 (14%), Positives = 52/149 (34%), Gaps = 21/149 (14%)

Query: 1   MRSYLILRL--AGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALS 58
           M+   ++R+   G + ++  P       T   P ++ ++G++ A +G  RDD   +++L 
Sbjct: 1   MKEIKLIRINAYGIINSFRIPLHMTIHDTLDLPVKTHIIGMIAAAMGYLRDDKEKIESLY 60

Query: 59  ESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV 118
           ++    +           + +   +     +         K++ TI     Y+       
Sbjct: 61  KNTSIGIYGTSYSKFYDLIRIYKYKGKEVEVSLVNRQINYKNNYTI-----YI------- 108

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLG 147
                      + E+   +  P +   LG
Sbjct: 109 -------ENNNLEEIYNFLKNPVFALSLG 130


>UniRef50_B0K553 CRISPR-associated protein Cas5, Hmari subtype n=4
           Tax=Thermoanaerobacter RepID=B0K553_THEPX
          Length = 236

 Score = 95.0 bits (235), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 36/225 (16%), Positives = 67/225 (29%), Gaps = 40/225 (17%)

Query: 16  WGQPTFEGTRPTGR------FPTRSGLLGLLGACLGIQRDD-TSSLQALSESVQFAVR-- 66
           WG+        T         P R+ + G++ A LG +RD     L A  E++  AVR  
Sbjct: 7   WGKFAHFRKFYTNSSSLTYSVPPRTTVEGMIAALLGYERDTYYEKLNA--ENLYVAVRKM 64

Query: 67  --CDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTP 124
               +++     +  T L + H      +    L   ++   +R Y+             
Sbjct: 65  SKTKKIMQSVNYIKATTLGELHFPKQHTQIPFELLISDSKIRYRFYI-----------IH 113

Query: 125 HATMVISELEKAV--LKPRYTPYLGRRSCPLTHPL--FLGTCQASDPQKALLN-----YE 175
               +  E+++ +    P +  Y G      + P   ++   +      A        Y 
Sbjct: 114 KDENIFREIKERLFKKAPVFPLYFG------SAPFSCYIDYVEEVTWDWATSEDFQDIYS 167

Query: 176 PVGGDIYSEESVTGHHLKFTARDEPMITL-PRQFASREWYVIKGG 219
            +  D   E  +            P      R       YV +  
Sbjct: 168 VMPSDKIKEIDIKNMKGYLLKERMPRDFGIDRTIKEVTTYVYEDV 212


>UniRef50_B5IGN1 CRISPR-associated protein Cas5 n=1 Tax=Aciduliprofundum boonei T469
           RepID=B5IGN1_9EURY
          Length = 236

 Score = 94.3 bits (233), Expect = 3e-18,   Method: Composition-based stats.
 Identities = 23/150 (15%), Positives = 50/150 (33%), Gaps = 21/150 (14%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGI-QRDDTSSLQALSES 60
              L  +L     ++ +        T   P  + ++GLLG+ LG+  R+  +    L++ 
Sbjct: 1   MEVLTAKLRAISVSFRRILDFNYHRTYPLPPPTTIVGLLGSALGLSDRELWNEYNGLND- 59

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWR--EYLCDASFTV 118
           + FAV                 +D  ++   +             + R   +     +  
Sbjct: 60  ISFAVLSLR--------KPGFAKDMWSIQKIKNGR---------ISERSPYFRELLFYPE 102

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGR 148
            + +    +  +  +  A+  P Y   LGR
Sbjct: 103 YVLIFNGDSKSLECVRDALNNPEYALSLGR 132


>UniRef50_Q1AZD3 CRISPR-associated protein, Cas5h family n=1 Tax=Rubrobacter
           xylanophilus DSM 9941 RepID=Q1AZD3_RUBXD
          Length = 258

 Score = 91.2 bits (225), Expect = 3e-17,   Method: Composition-based stats.
 Identities = 45/241 (18%), Positives = 75/241 (31%), Gaps = 37/241 (15%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           LI  L G    + +     +  +  FP R+ L GL+   +G +RD  +   +L E  Q A
Sbjct: 7   LIFDLCGAYGMFRKFYTNSSSLSYPFPPRTTLAGLIAGMMGCERDSYAEDLSL-ERCQIA 65

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETI-------------QTWREYL 111
           V     +    +     + + H        + G      +               +R Y 
Sbjct: 66  VSVITPVRRVMQQVNYVMTEGHVWTKNTGGFDGSSGPIQVPVEWVFPEVGHRELRYRVY- 124

Query: 112 CDASFTVALWLTPHATMVISELEKAVLK--PRYTPYLGRRSCP-------LTHPLFLGTC 162
                      T      +  L + +    P Y PYLG   CP             LG  
Sbjct: 125 ----------ATHEDRGWLKRLAEILEGGVPIYPPYLGMSECPGRVEHVATLEGWGLGHR 174

Query: 163 QASDPQKALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDV 222
           +   P + +L  E V G    EE V     +       +    R  A+ +    + G  +
Sbjct: 175 EDELPVRTVLPSEAVSGPPRLEEGVQIVKERI---PLALDERRRLIAAADVLYNRAGPHI 231

Query: 223 S 223
           +
Sbjct: 232 T 232


>UniRef50_B1I5P1 CRISPR-associated protein Cas5 n=2 Tax=Clostridia
           RepID=B1I5P1_DESAP
          Length = 238

 Score = 77.7 bits (190), Expect = 3e-13,   Method: Composition-based stats.
 Identities = 49/215 (22%), Positives = 75/215 (34%), Gaps = 38/215 (17%)

Query: 13  MQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDELIL 72
           M ++ +P     + T   P  + L GL GA  G+   +    Q  S         D L+ 
Sbjct: 1   MASFRRPLDHNYQRTLPLPPPTTLFGLAGAARGL--AEEELWQEASPL------RDLLVA 52

Query: 73  DDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPHATMVISE 132
                     RD  TV+  + +    +S      +RE L +A F +   L      +++E
Sbjct: 53  TLALQKPGLARDMWTVMKIKNNKLAERSPY----FREILFNARFMI---LYGGPEELLAE 105

Query: 133 LEKAVLKPRYTPYLGR-------------RSCPLTHPLFLGTCQASDPQKALLNYEPVGG 179
           L++A L P Y   LGR              +C    PLF GT    D Q     + P  G
Sbjct: 106 LQQAFLDPTYPLSLGREDELIVVEELGRGETC-PGAPLFSGTVIPGDLQGLRFKWVPRPG 164

Query: 180 DIYSEESVTGHHL---------KFTARDEPMITLP 205
             +   +V    L         ++     P   LP
Sbjct: 165 IAFEPPAVETMPLAFEVDKRGIRYPLNPRPFTFLP 199


>UniRef50_D1CHV1 CRISPR-associated protein Cas5 n=1 Tax=Thermobaculum terrenum ATCC
           BAA-798 RepID=D1CHV1_THET1
          Length = 264

 Score = 62.7 bits (151), Expect = 9e-09,   Method: Composition-based stats.
 Identities = 34/234 (14%), Positives = 63/234 (26%), Gaps = 45/234 (19%)

Query: 1   MR-SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQR-----DDTSSL 54
           M    +I  LAG    + +     +  +  FP R+ L GL+   +G +R          L
Sbjct: 1   MPNKMIIFDLAGAYAMFRKFYTNSSSLSYPFPPRTVLAGLIAGIMGYERQGHRNTYAEHL 60

Query: 55  QALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSH------------- 101
                 +  +VR    +    +     + + +        + G +               
Sbjct: 61  APGVADIALSVRV--PVRRVMQTVNYVMTEGNVWSRNAGGFDGSRERTLTPVEWVFPASG 118

Query: 102 ETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLK-PRYTPYLGRRSCPL------- 153
                +R YL           T      +      +     Y PYLG   CP        
Sbjct: 119 RRQLRYRVYL-----------THRDEGWLERFAGYLRSGAVYPPYLGMTECPAVIEPVAE 167

Query: 154 THPLFLGTCQASDPQKALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQ 207
                LG  +   P   ++N      D   +  +     +      P+     +
Sbjct: 168 VEDWELGVREEVLPISTVIN-----ADKIVDLPLPDADAQIVKERMPIALDNDR 216


>UniRef50_A5D0Y3 Putative uncharacterized protein n=1 Tax=Pelotomaculum
           thermopropionicum SI RepID=A5D0Y3_PELTS
          Length = 242

 Score = 59.2 bits (142), Expect = 9e-08,   Method: Composition-based stats.
 Identities = 46/224 (20%), Positives = 72/224 (32%), Gaps = 21/224 (9%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
             L+  + G +  + QP    T  T  FP R  + GLL + LG+  DD +    L E   
Sbjct: 4   QVLVFSIKGSLAHFRQPDTTATHATYPFPPRPTIHGLLASVLGLDFDDEAGAAFLHEEHF 63

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWL 122
             +   + +                 +  +    G        T  E +    + V    
Sbjct: 64  VGLSLLKPVRTVCA---------QMSMHGKGFTGGGGDSFNRLTTIELVVSPHYLVYYTG 114

Query: 123 TPHATMVISELEKAVL--KPRYTPYLGRRSCPLTHPLFLGTCQ----ASDPQKALLNYEP 176
           +      + EL + +   +  Y  YLG   C LT P+F G       A   ++ L     
Sbjct: 115 SR-----LGELAERIRTGQSVYHTYLGSAYC-LTFPVFHGLYPLLEVAPGEEEPLPCSSV 168

Query: 177 VGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGM 220
           V   +  E  V        AR  P   +  +F  R   VI    
Sbjct: 169 VPQGVIQEILVEPGGNYAVARALPYRHVGGRFFERTLNVIYEVN 212


>UniRef50_A3DHS3 CRISPR-associated protein Cas5 n=3 Tax=Clostridium thermocellum
           RepID=A3DHS3_CLOTH
          Length = 241

 Score = 57.7 bits (138), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 33/146 (22%), Positives = 52/146 (35%), Gaps = 17/146 (11%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              LI+ L     ++  P  +    T   P  S + G+ GA LG+  +D     AL+   
Sbjct: 1   MYGLIVTLYAKTASFRDPGAQLYHETMSLPPPSTITGIAGAALGLSFED-----ALAFMK 55

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           + AV        + R      +D        +   G  ++  I   R +L D    V ++
Sbjct: 56  ENAVMVGCNGSSEGRG-----KDLW---NYTKIKSGEITNAIII--RNFLADLK--VEIF 103

Query: 122 LTPHATMVISELEKAVLKPRYTPYLG 147
                  VI+ L  A   P Y   LG
Sbjct: 104 FACEKREVITRLADAFENPVYAITLG 129


>UniRef50_D1B1G1 CRISPR-associated protein Cas5 n=1 Tax=Sulfurospirillum deleyianum
           DSM 6946 RepID=D1B1G1_SULD5
          Length = 237

 Score = 57.7 bits (138), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 28/147 (19%), Positives = 54/147 (36%), Gaps = 18/147 (12%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGA-CLGIQRDDTSSLQALSES 60
              +   + G + ++  P F     T   P ++ ++GLL    L  Q++    L    E 
Sbjct: 1   MEAIRFEVEGLLNSFRVPFFRTYHKTFLAPPKTTIIGLLCNIALKSQKEFFEILN--QEL 58

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           +  +V  DE+            +D  +     +   G          R+ L  + +T+ L
Sbjct: 59  IDVSVIIDEING--------KTKDLWSYKTLEKGNMGKS-----VIRRDKLFLSKYTIYL 105

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLG 147
            +      +  E+  A+  P+ TP LG
Sbjct: 106 SIKNK--TLFDEIYSALKNPKNTPALG 130


>UniRef50_A7ZDW7 Crispr-associated protein Cas5 n=3 Tax=Campylobacter
           RepID=A7ZDW7_CAMC1
          Length = 236

 Score = 57.3 bits (137), Expect = 4e-07,   Method: Composition-based stats.
 Identities = 38/206 (18%), Positives = 66/206 (32%), Gaps = 23/206 (11%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGT------RPTGRFPTRSGLLGLLGACLGIQRDDTSSLQ 55
            S +  RL      +G               T   P ++ ++G LGA +G   +D   L 
Sbjct: 1   MSIVAFRL------FGDYAHFSHPATIYSSLTYPVPPKTTIMGFLGAVIG--EEDYFKLS 52

Query: 56  ALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDAS 115
            +  SV+   +  +       +      + H   G +         E  Q +RE +C  S
Sbjct: 53  NIQYSVKIDRQILKKSFVFNGIKFALSSNMHIEEGYQNAK------EKKQFYRELICSPS 106

Query: 116 FTVALWLTPHATMVISELEKAVL--KPRYTPYLGRRSCPLTHPLF-LGTCQASDPQKALL 172
           + V L L         ++   +   K  +TPYLG   C        +  C+     ++ +
Sbjct: 107 YVVFLNLENLEQSYQDKIISNLKEHKTAFTPYLGINFCIADFSWIDIKICEKISQDESFI 166

Query: 173 NYEPVGGDIYSEESVTGHHLKFTARD 198
           N   +  D   E       L      
Sbjct: 167 NTFTLMDDFVFEGINENAKLTTARMP 192


>UniRef50_A7HLK6 CRISPR-associated protein Cas5, Hmari subtype n=2
           Tax=Thermotogaceae RepID=A7HLK6_FERNB
          Length = 236

 Score = 56.9 bits (136), Expect = 5e-07,   Method: Composition-based stats.
 Identities = 33/244 (13%), Positives = 64/244 (26%), Gaps = 62/244 (25%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGR------FPTRSGLLGLLGACLGIQRDDTSSL- 54
             +L+  +       G+        T         P R+ L G++ A LG +RD    + 
Sbjct: 1   MEFLVFDIK------GKFAHFRKFYTNSSSLSYSIPPRTTLEGIIAAILGFERDSYYEIL 54

Query: 55  --QALSESVQFAVRCDELILDDRRVSVTGLR-----DYHTVLGAREDYRGLKSHETIQTW 107
             Q L+  ++ A    ++I     +           D HT     +    + +      +
Sbjct: 55  NAQKLNIGLKKATPTRKIIQTLNYIKAKTPSNVYDPDEHT-----QIPFEIITSNDKVIY 109

Query: 108 REYLCDASFTVALWLTPHATMVISELEKAVLKPRYT--PYLGRRSCPLTHPLFLGTCQAS 165
           R Y           +      ++ +LE  +   ++   PY G        P  +      
Sbjct: 110 RVY-----------VNHVDQTIMEDLEYRLKNNKFCYIPYFG------VAPFNISI---- 148

Query: 166 DPQKALLNYEPVGGDIYSEESV----------TGHHLKFTARDEPMITLPRQFASREWYV 215
           D +           D     SV              +       P          R    
Sbjct: 149 DLKGKFQAEPKFSEDFVKVSSVIRRNLISSLKVEEEVILLKEKMPRDFSR----ERTVIE 204

Query: 216 IKGG 219
           ++  
Sbjct: 205 MEDY 208


>UniRef50_C7P9L3 CRISPR-associated protein Cas5 n=2 Tax=Methanocaldococcus
           RepID=C7P9L3_METFA
          Length = 258

 Score = 56.5 bits (135), Expect = 6e-07,   Method: Composition-based stats.
 Identities = 23/170 (13%), Positives = 50/170 (29%), Gaps = 27/170 (15%)

Query: 2   RSYLILRLAGP-MQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
              L  R  G    ++ +P       T + P  + + GL+   LG+ RD           
Sbjct: 1   MWGLKFRCEGIYFVSFRKPVTTSLSLTYKLPPFTAIRGLIANALGMPRDSFEIQNWFKIG 60

Query: 61  VQFAVRCDELILDDRRVSVTGLR--------DYHTVLGAREDYRGLKSHETIQT------ 106
           ++   + +      + + +   +         +  +  ++         E +        
Sbjct: 61  MRVEGKIEIGREMAKFLKMISRKSCYRCENCRFEKIADSKPKKCPNCGKENLVKVEKMIY 120

Query: 107 ---------WREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLG 147
                     RE+L    + + L         I ++  A+  P    YLG
Sbjct: 121 ERAFPSSPMHREFLIMPKYWIYLV---GEEKKIKKIYYALKSPERPLYLG 167


>UniRef50_D0MJ68 CRISPR-associated protein Cas5 n=1 Tax=Rhodothermus marinus DSM
           4252 RepID=D0MJ68_RHOM4
          Length = 236

 Score = 55.0 bits (131), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 36/144 (25%), Positives = 54/144 (37%), Gaps = 17/144 (11%)

Query: 8   RLAGPMQAWGQPTFE--GTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAV 65
            LAGP+ ++  P     G +PT   P  S + GL+ A LG   D         E++QFA 
Sbjct: 12  ELAGPVASFRYP-HFLIGRQPTYPMPPPSTIYGLISAALGRFPD--------PEALQFAY 62

Query: 66  RCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPH 125
           R +        V        +T        + L++   I   RE+L     T+ +     
Sbjct: 63  RFECARHRVDDVETIWFVQPNTATRGEAARKNLEATSNILP-REWLVHPRLTLYVTGDE- 120

Query: 126 ATMVISELEKAVLKPRYTPYLGRR 149
               +  L +A   P Y   LGR 
Sbjct: 121 ----LEALYRAFRSPCYILTLGRS 140


>UniRef50_B7R550 CRISPR-associated protein Cas5 n=1 Tax=Thermococcus sp. AM4
           RepID=B7R550_9EURY
          Length = 275

 Score = 54.6 bits (130), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 27/159 (16%), Positives = 50/159 (31%), Gaps = 17/159 (10%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACL----GIQRDDTSSLQALS 58
             L++ L  P   +  P       T   P +S ++G+L   L    G +R          
Sbjct: 4   KTLLIELFQPFAQYRNPFTFYYAQTYPLPPKSTIIGMLQNALNDWYGNERGIDEWWN--- 60

Query: 59  ESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL------KSHETIQTWRE-YL 111
             ++ +V      +      +         +        L           + + R   L
Sbjct: 61  --LRVSVHGGFESVFWNYQQLIKATKTGISIVRFRGKPTLWNQKLPLYGFPVTSQRSPVL 118

Query: 112 CDASFTVALW-LTPHATMVISELEKAVLKPRYTPYLGRR 149
               F   L+ L       +SE+++A+ +PR    LGR 
Sbjct: 119 QQELFNGWLYILLKGEEEFLSEIKEALERPRKVISLGRS 157


>UniRef50_C9RCY2 CRISPR-associated protein Cas5, Hmari subtype n=2
           Tax=Thermoanaerobacteraceae RepID=C9RCY2_AMMDK
          Length = 266

 Score = 54.2 bits (129), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 36/160 (22%), Positives = 56/160 (35%), Gaps = 25/160 (15%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M +  +  L GP   + +     +  +  FP R+ L+G + A LG +RD       LSE+
Sbjct: 1   MVNVAVFDLVGPFAHFRKYYTNSSSLSYAFPPRTALMGTVAAVLGWERDSYYEKLGLSEA 60

Query: 61  VQFA----VRCDELILDDRRVSVT-----GLRDYHTVLGAREDYRGLKSHETIQT--WRE 109
            +FA    V    LI     +         LR    V G +     L    T  +  +R 
Sbjct: 61  -RFAVVIKVPVRRLIQTVNYIRTKEEDLNRLRKLEAVKGTQVPLELLLPGGTASSLCFRV 119

Query: 110 YLCDASFTVALWLTPHATMVISELEKAVL--KPRYTPYLG 147
           Y                  V  EL + +   +  +  YLG
Sbjct: 120 YFA-----------HRDDQVTRELAERLAAGRSYFPLYLG 148


>UniRef50_B5YBH8 CRISPR-associated protein Cas5, Hmari subtype n=1 Tax=Dictyoglomus
           thermophilum H-6-12 RepID=B5YBH8_DICT6
          Length = 250

 Score = 53.1 bits (126), Expect = 8e-06,   Method: Composition-based stats.
 Identities = 24/157 (15%), Positives = 54/157 (34%), Gaps = 24/157 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES- 60
              ++  L G M  + +     +  +  FP R+ ++GL+   LG +RD    + +  ++ 
Sbjct: 1   MKVIVFDLLGKMAHFRKFYTNSSSLSYHFPPRTTIVGLIAGLLGYERDTYYEIFSTDKAK 60

Query: 61  VQFAVR--------CDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLC 112
           +   V+            +  +    +   R  HT     E        E    +R    
Sbjct: 61  ITIGVKSPLRKILQVVNYVWAENVKQLNQSRGQHT-QIPLEIIFPQDMKE-DICYR---- 114

Query: 113 DASFTVALWLTPHATMVISELEKAVLK--PRYTPYLG 147
                  ++       ++ +L+  ++     + PYLG
Sbjct: 115 -------IFFHHKDEKIMEDLKNKLVNFDFCFPPYLG 144


>UniRef50_C6QNG6 CRISPR-associated protein Cas5, Hmari subtype n=1 Tax=Geobacillus
           sp. Y4.1MC1 RepID=C6QNG6_9BACI
          Length = 244

 Score = 52.7 bits (125), Expect = 8e-06,   Method: Composition-based stats.
 Identities = 28/157 (17%), Positives = 50/157 (31%), Gaps = 25/157 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              LI  L G M  + +     +  +  FP R+ ++G++   LG++RD    + +  +  
Sbjct: 1   MKMLIFDLIGKMGHFRKIDTNSSSLSYAFPPRTTIVGMIAGILGMERDSYYEVFS-PDQC 59

Query: 62  QFAVRCDELILDDRRVSVTGLR---------DYHTVLGAREDYRGLKSHETIQTWREYLC 112
           Q A+     I    +                  HT     E        E    +R Y  
Sbjct: 60  QIAISVRTPIRKVMQTVNYMFVKSKAHLNNSGGHT-QIPLEFVLPG-GEEANLRYRIY-- 115

Query: 113 DASFTVALWLTPHATMVISELEKAVLKP--RYTPYLG 147
                     +     V   +++ +      Y PYLG
Sbjct: 116 ---------FSHSDRSVYESVKERIQSGRYVYPPYLG 143


>UniRef50_O27159 Putative uncharacterized protein n=1 Tax=Methanothermobacter
           thermautotrophicus str. Delta H RepID=O27159_METTH
          Length = 269

 Score = 52.7 bits (125), Expect = 9e-06,   Method: Composition-based stats.
 Identities = 24/153 (15%), Positives = 47/153 (30%), Gaps = 11/153 (7%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L + +  P   +  P       T     +S + G+L    G  R     +  +S S+
Sbjct: 1   METLAVEIFQPFAQFRNPFTFDYAQTYPLSPKSTVTGMLQNATG--RYYDQDISEISVSI 58

Query: 62  QFAVRCDELILDDRRVSVTGLRDYH-----TVLGAREDYRGLKSHETIQTWREYLCDASF 116
              +           +       YH             Y   K  +   ++++ L +  +
Sbjct: 59  H-GLFESTFWNYQSFIVGDIALKYHHNKLKLWNKGYPLYSVNKKSQRSPSYQQELFNGHY 117

Query: 117 TVALWLTPHATMVISELEKAVLKPRYTPYLGRR 149
            + L        +I E+  ++ KP     LGR 
Sbjct: 118 YIFLR---GDDDIIEEVCDSLRKPTKPLSLGRS 147


>UniRef50_D1A6P6 Metal dependent phosphohydrolase n=1 Tax=Thermomonospora curvata
           DSM 43183 RepID=D1A6P6_THECD
          Length = 1027

 Score = 51.9 bits (123), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 26/147 (17%), Positives = 41/147 (27%), Gaps = 26/147 (17%)

Query: 8   RLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVRC 67
           +L  P+ ++  P F G       P  S L G+L A  G            +E V   V  
Sbjct: 14  QLYAPVASFRDPMFPGVTRCLPVPPPSTLRGMLAAATGRP----------AEPVVLGV-- 61

Query: 68  DELILDDRRVSVTGLRDYH-TVLGAREDYRGLK----SHETIQTWREYLCDASFTVALWL 122
                            YH           G +            R +L     T+ + +
Sbjct: 62  ----CAYAEGRGVDTETYHPIAADGSNPAIGGRVRPGKGGMTIRERPFLTGVHITLWVPM 117

Query: 123 TPHATMVISELEKAVLKPRYTPYLGRR 149
                     +  A+ +P +   LGR 
Sbjct: 118 PDG-----ERIATALRRPTWGLRLGRS 139


>UniRef50_A4J1X9 CRISPR-associated protein Cas5, Hmari subtype n=1
           Tax=Desulfotomaculum reducens MI-1 RepID=A4J1X9_DESRM
          Length = 242

 Score = 51.5 bits (122), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 31/151 (20%), Positives = 61/151 (40%), Gaps = 9/151 (5%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDD-TSSLQALSE 59
           M   +  RL+G    + +     +  +   P R+ LLG+LGA LG+++D     L+ L  
Sbjct: 1   MMKLIAFRLSGRFGHFLRAEAGTSALSYPVPPRTVLLGILGAVLGLEKDLPQELLEPLHI 60

Query: 60  SVQFAVRCDELILDD-RRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV 118
           ++   V          R+     L     V   ++  +  K        +E+L + ++T+
Sbjct: 61  ALAGPVPQSHWHKAKLRKDPPEALP--QVVKNNQKQEKTTKPEMATLITQEWLFNPAYTI 118

Query: 119 ALWLTPHATMVISELEKAVLKP--RYTPYLG 147
            + L         +LE+ + +    + P LG
Sbjct: 119 WVALP---EPYHQQLEQRLKERCWHFQPCLG 146


>UniRef50_O57910 Putative uncharacterized protein PH0171 n=1 Tax=Pyrococcus
           horikoshii RepID=O57910_PYRHO
          Length = 227

 Score = 51.1 bits (121), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 33/218 (15%), Positives = 68/218 (31%), Gaps = 25/218 (11%)

Query: 1   MRSYLILRLAG-PMQA-WGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALS 58
           M   L L +   P+QA +  P       T  FP ++  +G+L  C+G+        + L 
Sbjct: 1   MSELLGLIVDARPLQAHFRIPHTSLLLDTYPFPPKTTAVGMLAGCMGLG---EEGFKKLL 57

Query: 59  ESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV 118
           E +++ V  +             + +   +              +    R  L    F +
Sbjct: 58  EKIKYGVIIE--------DPGEKIEEVSVIYK-------NPYSPSYPITRVSLYKPRFRM 102

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGRRS--CPLTHPLFLGTCQASDPQKALLNYEP 176
                     VI E  + +L P++ PY+G            ++      + ++ +L    
Sbjct: 103 FFA---GEERVIEEAYEGLLDPKFVPYMGDSESLFYPGKKRYVEVVDVQEGKEDILRSVI 159

Query: 177 VGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWY 214
                     +    L     + P+    +  + R  Y
Sbjct: 160 PEVKFKEFVPLRRKVLVPKVYEAPVKFTYKGKSRRAVY 197


>UniRef50_Q2NH81 Putative uncharacterized protein n=1 Tax=Methanosphaera stadtmanae
           DSM 3091 RepID=Q2NH81_METST
          Length = 235

 Score = 50.4 bits (119), Expect = 4e-05,   Method: Composition-based stats.
 Identities = 30/150 (20%), Positives = 50/150 (33%), Gaps = 16/150 (10%)

Query: 16  WGQPTFEGTRPT------GRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDE 69
           WG   +     T        FP+R+ + G +   LG  R+    L    E+ +  ++   
Sbjct: 9   WGDYAYFRRGYTTTSTLTYPFPSRTTIAGFIAGILGYPRNSYYDL-FQKENSKIGLKIIN 67

Query: 70  LILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPHATMV 129
            I   R          +T               T     E+L +  + + L L      +
Sbjct: 68  PIKKTRINLNYI----NTKNSMLLSEIKGNGKRTQVPA-EFLKNVKYRIYLSL--DDEEI 120

Query: 130 ISELEKAVL--KPRYTPYLGRRSCPLTHPL 157
           +++L   +   K  YTPYLG   C     L
Sbjct: 121 MNKLYNTLKEHKSVYTPYLGITECLANFSL 150


>UniRef50_B1LAM2 CRISPR-associated protein Cas5, Hmari subtype n=2 Tax=Thermotoga
           RepID=B1LAM2_THESQ
          Length = 220

 Score = 50.4 bits (119), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 32/170 (18%), Positives = 60/170 (35%), Gaps = 23/170 (13%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L+  ++     + +P    +  T  FP R+ LLGL+G  LG        L +   +V
Sbjct: 1   MKVLVFDVSTSYALFRRPYTTTSSYTLPFPPRTALLGLVGCVLGY--STPEKLDSAKVAV 58

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           Q             +  +  LR   T     E  +  K+ +  +   + L + ++ V   
Sbjct: 59  QI------------KNPLKFLR---TGTNFVETKKDKKASKRTRISLQLLKNPAYRVFFS 103

Query: 122 LTPHATMVISELEKAVLK--PRYTPYLGRRSCPLTHPLFLGTCQASDPQK 169
                      L+  +      +TPYLG  S       ++G  +A+  + 
Sbjct: 104 WEDKD---FERLKNLLEHNETIFTPYLGVASFIAKLD-YVGEYEATRVED 149


>UniRef50_D2QT47 CRISPR-associated protein Cas5 n=1 Tax=Spirosoma linguale DSM 74
           RepID=D2QT47_9SPHI
          Length = 237

 Score = 49.2 bits (116), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 26/143 (18%), Positives = 42/143 (29%), Gaps = 21/143 (14%)

Query: 6   ILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGI-QRDDTSSLQALSESVQFA 64
            + L     ++  P F+    +   P  + L+GL GA LG+  R     L          
Sbjct: 5   TIELKSVTASFRNPEFQNFHKSFPLPPPTALIGLAGAALGLSPRMAQDFLD--------- 55

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTP 124
              ++             RD          Y  L    +    RE   +  +   L    
Sbjct: 56  --TNQFQAGVSGKGEGMTRDLW-------KYDRLTGTGSSIILREIYVNPHY--RLVFGS 104

Query: 125 HATMVISELEKAVLKPRYTPYLG 147
                + +L+ A   P Y   LG
Sbjct: 105 DNHEAVEQLKAAFDSPVYALTLG 127


>UniRef50_A3XI99 Putative uncharacterized protein n=1 Tax=Leeuwenhoekiella
           blandensis MED217 RepID=A3XI99_9FLAO
          Length = 243

 Score = 48.8 bits (115), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 24/148 (16%), Positives = 48/148 (32%), Gaps = 15/148 (10%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQ--RDDTSSLQALSE 59
               I+ +     ++  P F+    +   P  + ++G+ GA LG    R      ++  E
Sbjct: 1   MKNFIIEIQCQTASFRNPDFQNFHKSLELPPPTTVIGIAGAALGYSPLRAQEFFDESKFE 60

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
              +     +     +      +RD                 +     RE+L   +F +A
Sbjct: 61  IGIYGTYLGKCKDTWKYNKG--IRDM---------RLYDPGLDGSIIQREFLIFPTFIIA 109

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLG 147
              +      + +L KA   P Y   +G
Sbjct: 110 --FSSENIKAVEKLYKAFTSPVYALTMG 135


>UniRef50_C7NNV3 CRISPR-associated protein Cas5, Hmari subtype n=3
           Tax=Halobacteriaceae RepID=C7NNV3_HALUD
          Length = 264

 Score = 48.1 bits (113), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 38/213 (17%), Positives = 63/213 (29%), Gaps = 21/213 (9%)

Query: 5   LILRLAGPMQAWGQPTFEG---TRPTGRFPTRSGLLGLLGACLGIQRDDTSSL--QALSE 59
           L   + GP   WG          + T R   R+ + GL+ A LGI RD    L    +S 
Sbjct: 21  LSFEIRGP---WGHFRRVEGNVVKQTYRIVPRTTVAGLIAAVLGIDRDGYYDLFGPEVSA 77

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWRE-Y--LCDASF 116
                V     +        T   D  T L  R        + T    +  Y  L D ++
Sbjct: 78  IAIQPVEELRTVNMPMNTLSTAAGDL-TSLNPRGKISIKLPNPTKLRQQHNYEVLVDPAY 136

Query: 117 TVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEP 176
            + + L         +L + +         G+     +  L     +     +  +   P
Sbjct: 137 RIDVALADDERY--EQLRETLAA-------GKSHYVPSLGLSEYLAEIDYLGEFDVKPGP 187

Query: 177 VGGDIYSEESVTGHHLKFTARDEPMITLPRQFA 209
             G I  + +V           E    + +  A
Sbjct: 188 ASGTIAVDSAVPDAMDDVVLDPETRCQIEQSPA 220


>UniRef50_C8PE23 CRISPR-associated protein Cas5 n=1 Tax=Campylobacter gracilis
           RM3268 RepID=C8PE23_9PROT
          Length = 237

 Score = 48.1 bits (113), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 28/152 (18%), Positives = 56/152 (36%), Gaps = 10/152 (6%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              +   L+G    +  P    +  T   P ++ ++GLLGA +G    +   L  +  SV
Sbjct: 1   MDIIAFELSGDYAHFSHPATIYSSLTYPVPPKTAIMGLLGAIIG--EMNYFKLNDIGYSV 58

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
             + +  +  +    +        H   G         S E  Q ++E + D  + + + 
Sbjct: 59  ILSSQFRKKTMIFNGIKFALSSSMHIEQG------YQDSSEKKQFYKELIKDPRYVIFVD 112

Query: 122 LTPHATMVISELEKAVL--KPRYTPYLGRRSC 151
           L+         +  ++   +  +TPYLG   C
Sbjct: 113 LSALNASYKENIIDSLKAHRCVFTPYLGINFC 144


>UniRef50_B9MPU1 CRISPR-associated protein Cas5, Hmari subtype n=2 Tax=Clostridia
           RepID=B9MPU1_ANATD
          Length = 250

 Score = 47.3 bits (111), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 29/183 (15%), Positives = 57/183 (31%), Gaps = 36/183 (19%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGR------FPTRSGLLGLLGACLGIQRDDTSSLQ 55
             +L+  L       G+        T         P R+ + G++ A LG +RD    + 
Sbjct: 1   MKFLVFDLK------GKFAHFRKFYTNSSSLSYLVPPRTVIEGMVAAILGFERDSYYDMF 54

Query: 56  ALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLC--D 113
           + +E++  AV        ++   +    +Y       E        +      E L   +
Sbjct: 55  S-AENLLVAV-----QKLEKTYKIVQTVNYIKAQTISELKNPNTHTQVPL---EILAGYN 105

Query: 114 ASFTVALWLTPHATMVISELEKAVLK--PRYTPYLGRRSCPLTHPL-----FLGTCQASD 166
                 +++ P    + S L   +      +  Y G      + P      FLG  +A  
Sbjct: 106 GFVGFRVFVMPKDEKIYSFLRARLESGKSEFPIYFG------SAPFAAKIEFLGEFEACR 159

Query: 167 PQK 169
            + 
Sbjct: 160 WED 162


>UniRef50_B1B9K0 Crispr-associated protein Cas5, tneap subtype n=1 Tax=Clostridium
           botulinum C str. Eklund RepID=B1B9K0_CLOBO
          Length = 244

 Score = 47.3 bits (111), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 24/150 (16%), Positives = 54/150 (36%), Gaps = 11/150 (7%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQ-ALSES 60
              ++L++   +  + +PT    + T   P  S ++G++ A  G   D+   ++ ++  +
Sbjct: 1   MKAILLKVTQNLVNYKKPTSFQLKETYPLPPYSTVIGMVHAACGF--DEYKDMEVSIQGN 58

Query: 61  VQFAVRCDELILDDRRVSVTGLRDY-HTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
               V     +      +     D  H +    ED           +  E L D    + 
Sbjct: 59  YHSKV---NDLYTRYEFAGASYEDKRHNIKLKGEDKYYGAMRG--VSTCELLVDVELLIH 113

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRR 149
           +   P    +I  + + +  P+    +GRR
Sbjct: 114 I--KPKDENLIQIIYQNLKYPKEYLSIGRR 141


>UniRef50_A3DKB9 CRISPR-associated protein Cas5, Hmari subtype n=2 Tax=Clostridium
           thermocellum RepID=A3DKB9_CLOTH
          Length = 237

 Score = 46.9 bits (110), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 27/149 (18%), Positives = 53/149 (35%), Gaps = 26/149 (17%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSL-QALSESV 61
            YL+  ++     + +P    +  T   PTR+ + G++ A LG  ++D           +
Sbjct: 4   KYLVFDISASYGHFKKPYTTTSPLTYSIPTRTAVSGIIAAVLGFGKEDYQEHFTKPQAKI 63

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWR-----EYLCDASF 116
              +R            V  +R         E+    K    I   R     E+L DA +
Sbjct: 64  AIGIR----------NPVKKVR-------ISENLINTKKSMNIIHERTQIKIEFLKDACY 106

Query: 117 TVALWLTPHATMVISELEKAVLKPRYTPY 145
              ++ T     +   L++++ +   T Y
Sbjct: 107 --RIYFTHTDKQIYERLKESLKE-HRTVY 132


>UniRef50_C8VZL1 CRISPR-associated protein Cas5 n=1 Tax=Desulfotomaculum
          acetoxidans DSM 771 RepID=C8VZL1_DESAS
          Length = 253

 Score = 46.1 bits (108), Expect = 8e-04,   Method: Composition-based stats.
 Identities = 15/64 (23%), Positives = 29/64 (45%), Gaps = 1/64 (1%)

Query: 2  RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             +   L G M  + +     +  +   P R+ L+G++   LG +RD    + +L+ S 
Sbjct: 1  MKIISFHLRGKMAHFRRYYANSSALSYSIPPRTTLIGIVAGLLGWERDKYYEIFSLN-SC 59

Query: 62 QFAV 65
          + AV
Sbjct: 60 KVAV 63


>UniRef50_B1I4M5 CRISPR-associated protein Cas5 family n=1 Tax=Candidatus
           Desulforudis audaxviator MP104C RepID=B1I4M5_DESAP
          Length = 255

 Score = 46.1 bits (108), Expect = 8e-04,   Method: Composition-based stats.
 Identities = 23/153 (15%), Positives = 51/153 (33%), Gaps = 24/153 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFE--GTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE 59
                + +  P+ ++  P     G + +   P  S + G + + +G    +  +   +  
Sbjct: 1   MRVAKVHIEAPIASFRYP-HFLIGRQTSFDMPPPSTIYGHIASAVG----EWFNPATVKF 55

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREY---LCDASF 116
           + QF+           +   + L   H +    + ++  +    + T       L D  F
Sbjct: 56  AYQFS----------FQAKGSDLEHQHVITKGGQTFKWGERKYPVSTQAVVQPHLRDFLF 105

Query: 117 TVALWLTPHATMVISELEKAVLKPRYTPYLGRR 149
              L L  +      +L +A   P +   LGR 
Sbjct: 106 GCRLTLYLYPP----DLAEAFRNPVFCVILGRS 134


>UniRef50_Q3M7D6 Fruiting body developmental protein S-like protein n=3
           Tax=Cyanobacteria RepID=Q3M7D6_ANAVT
          Length = 210

 Score = 46.1 bits (108), Expect = 0.001,   Method: Composition-based stats.
 Identities = 22/142 (15%), Positives = 46/142 (32%), Gaps = 17/142 (11%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + + L++  P+  + Q        T   P  S + G+L + +G    +    +     +
Sbjct: 1   MTTIALKVEVPIACFRQSRAREYGETYPVPPPSTVYGMLLSLVG----EVDRYKHCGVKL 56

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
             A       L       T +R +H      +      S      ++E L +  F V + 
Sbjct: 57  AIA-------LLSEPEKSTVIRTFH----RFKTKNIHDSKNNKPDYQELLTNIEFIVWVD 105

Query: 122 LTPH--ATMVISELEKAVLKPR 141
                    ++  L +A+  P 
Sbjct: 106 AGVDKAKPNLVERLAEALTNPA 127


>UniRef50_C1DUR1 Crispr-associated protein Cas5, hmari subtype n=1
           Tax=Sulfurihydrogenibium azorense Az-Fu1
           RepID=C1DUR1_SULAA
          Length = 229

 Score = 45.7 bits (107), Expect = 0.001,   Method: Composition-based stats.
 Identities = 28/154 (18%), Positives = 52/154 (33%), Gaps = 27/154 (17%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPT------GRFPTRSGLLGLLGACLGIQRDDTSSLQ 55
              L+  +      WG         T         P  + + G++GA LGI + D   + 
Sbjct: 1   MEVLVFDV------WGDFGHFRKFYTTTSPLTFSIPPPTAVFGIIGAILGIDKKDYLKII 54

Query: 56  ALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDAS 115
             +E+ + A+   + +   R           T+          +         E+L DA 
Sbjct: 55  N-AETTKVAIEIVKPVKKIRF----------TINYIDTKVSFSRIKNRTPIRTEFLKDAH 103

Query: 116 FTVALWLTPHATMVISELEKAV--LKPRYTPYLG 147
           + + + L  +   +  EL+  +   K  YT  LG
Sbjct: 104 YRLYINL--NEENLFRELKDRIKERKTYYTVSLG 135


>UniRef50_A7BQN4 Protein containing DUF522 n=1 Tax=Beggiatoa sp. PS
           RepID=A7BQN4_9GAMM
          Length = 267

 Score = 45.7 bits (107), Expect = 0.001,   Method: Composition-based stats.
 Identities = 30/132 (22%), Positives = 56/132 (42%), Gaps = 16/132 (12%)

Query: 27  TGRFPTRSGLLGLLGACLGIQRDDTSSLQALS-ESVQFAVRCDELILDDRRVSVTGLRDY 85
           T  FP  + ++GLLGA LG  +++    + L  ++++  +R  +     R  ++  L   
Sbjct: 47  TYPFPPPTAIMGLLGAILGYSKEEY--HERLGWQTLRVGIRLLKPTQIFR-AAINLL--- 100

Query: 86  HTVLGAREDYRGLKSHETIQTWR---EYLCDASFTVALWLTPHATMVISELEKAVL--KP 140
            T  G    +R      +    R   E++   ++ + +   P    V S+L   +   + 
Sbjct: 101 QTKDGTDTFFRPKADKNSH--TRVPYEFVKSPAYRIYVMQLPD--NVASDLVAHLKTHRT 156

Query: 141 RYTPYLGRRSCP 152
            YTP LG  SC 
Sbjct: 157 VYTPVLGLASCL 168


>UniRef50_B8CYA3 CRISPR-associated protein Cas5 n=1 Tax=Halothermothrix orenii H 168
           RepID=B8CYA3_HALOH
          Length = 238

 Score = 45.4 bits (106), Expect = 0.002,   Method: Composition-based stats.
 Identities = 26/158 (16%), Positives = 55/158 (34%), Gaps = 19/158 (12%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
             L+ ++ G +  + +     +  T + P R+ L+G++ + L   RD    L +  ++ +
Sbjct: 5   QVLVFKIKGKIAHFKKYYSNKSSLTYKIPPRTVLMGIVASILEKPRDSYYELLSPQQA-K 63

Query: 63  FAVRCDELILDDRRVSVTGLRD-YHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           F V+ +               D  HT          L ++    +++ +           
Sbjct: 64  FGVKIESESYTHFECMNYLKEDGGHT---QVRLQLLLPANNM-LSYKVF----------- 108

Query: 122 LTPHATMVISELEKAVLKPR--YTPYLGRRSCPLTHPL 157
            T     ++ EL   +      Y  YLG+R    T   
Sbjct: 109 FTHQDESLLKELATKIKNKIYGYGIYLGQRQFRATAEF 146


>UniRef50_Q8PZD2 Putative uncharacterized protein n=1 Tax=Methanosarcina mazei
           RepID=Q8PZD2_METMA
          Length = 232

 Score = 45.0 bits (105), Expect = 0.002,   Method: Composition-based stats.
 Identities = 21/115 (18%), Positives = 43/115 (37%), Gaps = 20/115 (17%)

Query: 35  GLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGARED 94
            + GL+GA LGI + +   +   +  ++  ++    +           +D   +      
Sbjct: 34  AVKGLIGAVLGIDKTE---IYRNTLDLKIGIQVLSPVR----------KDMQVLKLVSMK 80

Query: 95  YRGLKSHETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLK--PRYTPYLG 147
                 +  +    E+L D  + + +   P     + ELE  +    P +TPYLG
Sbjct: 81  AEKDLFNFPV--NAEFLRDPEYRIFVSWLPDK---LDELEDRLQNQMPIFTPYLG 130


>UniRef50_A1ZVP9 Crispr-associated protein Cas5, tneap subtype n=1 Tax=Microscilla
           marina ATCC 23134 RepID=A1ZVP9_9SPHI
          Length = 218

 Score = 44.2 bits (103), Expect = 0.003,   Method: Composition-based stats.
 Identities = 23/124 (18%), Positives = 35/124 (28%), Gaps = 26/124 (20%)

Query: 26  PTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDY 85
           PT   P  S +LGL+ A  G       +   L     F                +   D 
Sbjct: 26  PTLEVPPVSTVLGLINAAAGH----YVAHSTLKLGYYF-------------EYQSKAVDL 68

Query: 86  HTV-LGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTP 144
            T+              ++    RE+L +A   + +           E+      P Y  
Sbjct: 69  ETIYQIGAHKGMPSNHAKSNIIRREFLFEAFLRLYVTS--------QEVADYFRSPVYPI 120

Query: 145 YLGR 148
            LGR
Sbjct: 121 VLGR 124


>UniRef50_A8F3P0 CRISPR-associated protein Cas5, Hmari subtype n=1 Tax=Thermotoga
           lettingae TMO RepID=A8F3P0_THELT
          Length = 230

 Score = 43.8 bits (102), Expect = 0.004,   Method: Composition-based stats.
 Identities = 26/150 (17%), Positives = 53/150 (35%), Gaps = 21/150 (14%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRD--DTSSLQALSE 59
              ++  + G    + +     +  +  FP R+ + GLLGA +GIQ +    S    + +
Sbjct: 1   MKVIVFDVKGKYALFRRNYTTSSSTSYNFPPRTSICGLLGAIMGIQNEATQFSKHLRIFD 60

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
           +   A+R    I               T+     + +  K+  T     E + +  + + 
Sbjct: 61  NAHIALRVLVPIRKT------------TMGVNYAETKSGKNQRTQII-LELIKEPVYRIY 107

Query: 120 LWLTPHATMVISELEKAVLKP--RYTPYLG 147
           +           +L   +      +TPYLG
Sbjct: 108 VS----EFSQFDQLRNHLENNTCVFTPYLG 133


>UniRef50_A4XGC7 CRISPR-associated protein Cas5 family n=1
          Tax=Caldicellulosiruptor saccharolyticus DSM 8903
          RepID=A4XGC7_CALS8
          Length = 275

 Score = 43.0 bits (100), Expect = 0.008,   Method: Composition-based stats.
 Identities = 14/53 (26%), Positives = 22/53 (41%), Gaps = 6/53 (11%)

Query: 1  MRSY------LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQ 47
          M+        L +++  P   +  P     R T   P  S +LGL+   LGI+
Sbjct: 1  MKETKNSIYALKIKIYQPQAHFRIPFSYQRRHTYPIPPYSTVLGLIANILGIK 53


>UniRef50_D1QSA9 CRISPR-associated protein Cas5, Tneap subtype n=1 Tax=Prevotella
           oris F0302 RepID=D1QSA9_9BACT
          Length = 224

 Score = 41.1 bits (95), Expect = 0.026,   Method: Composition-based stats.
 Identities = 29/155 (18%), Positives = 51/155 (32%), Gaps = 28/155 (18%)

Query: 2   RSYLILRLAGPMQAWGQP-TFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
                ++++    ++  P    G +PT   P  S +LGL+ AC G       +   +   
Sbjct: 1   MKVFRIKISAWTASFRYPNIISGYQPTLEVPPLSTILGLMNACAGR----YLNHADMEIG 56

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSH-ETIQTWREYLCDASFTVA 119
             F  R                 D  T+   + D    K   ++    R++L D +  + 
Sbjct: 57  YYFNYRSIS-------------NDLETIYQMKYDKGTAKKQVKSNVINRQFLFDNTLYIY 103

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLT 154
           +           +  K    P +   LGR SC L 
Sbjct: 104 IID--------KDFVKYFQTPAFQILLGR-SCDLA 129


>UniRef50_B9LWL0 CRISPR-associated protein Cas5, Hmari subtype n=1 Tax=Halorubrum
           lacusprofundi ATCC 49239 RepID=B9LWL0_HALLT
          Length = 265

 Score = 40.7 bits (94), Expect = 0.041,   Method: Composition-based stats.
 Identities = 36/220 (16%), Positives = 57/220 (25%), Gaps = 51/220 (23%)

Query: 16  WGQPTFEGT---RPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDELIL 72
           WG     G    + T R P R+ + G+L A +G  RD                  D    
Sbjct: 23  WGHFKRVGRSVTKQTYRIPPRTTVAGMLAAIVGSDRDSYY---------------DVFGA 67

Query: 73  DDRRVSVTGLRDYHTVLGAREDYRGLKS---HETIQTWREY------------------L 111
           D   +++T L D  TV                +T  + R Y                  L
Sbjct: 68  DTSAIAITPLFDIRTVNVPTTGLGTDPKQAVTKTAGSRRSYALTYQDTEGDRQIHAYELL 127

Query: 112 CDASF--TVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQK 169
            D  +   VA+    +   +   L+    +  Y P LG+                     
Sbjct: 128 TDPVYRIDVAVEDEAYYEKLERRLDN--EESYYPPSLGKSEYL--------CTVEDVETD 177

Query: 170 ALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFA 209
                         +  V G   +   +      + R  A
Sbjct: 178 VSPTELAEAEQYDVDSVVPGSLSEVIPQQGVTYDIERSPA 217


>UniRef50_A1HND7 CRISPR-associated protein Cas5 family n=1 Tax=Thermosinus
           carboxydivorans Nor1 RepID=A1HND7_9FIRM
          Length = 257

 Score = 40.0 bits (92), Expect = 0.063,   Method: Composition-based stats.
 Identities = 40/228 (17%), Positives = 72/228 (31%), Gaps = 23/228 (10%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTR-PTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             L + ++    ++  P     R PT   P  + + G L    G    +  +   L  S 
Sbjct: 6   DVLKIEMSAMTASFRYPHVMIGRLPTFEMPPPATIYGHLCGVWG----EWFNPGDLEFSY 61

Query: 62  QF---AVRCD-ELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFT 117
            F    +  D EL       S    +   T+ G  ++ +G  + +     R++L     T
Sbjct: 62  VFTHGGIGEDVELGHMIEFGSGRSEK---TLGGLPKNMKGSLNPQ----RRQFLFRPRMT 114

Query: 118 VALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLT--HPLFLGTCQASDPQKALLNYE 175
           + L        ++  LE+A   P +   LGR     T     +    QAS    A     
Sbjct: 115 LYLK---GDDKILQRLEQAFKSPAFAYILGRSQDLATVHSITWARLKQASGAFFANTLLP 171

Query: 176 PVGGDIYS--EESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMD 221
                  S          + +    EP+     +   R   +   G++
Sbjct: 172 WTLRQWVSVGRPVYMPKWINYHKLREPVFERYLEIDDRPLRIFGEGVE 219


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_Q46898 Uncharacterized protein ygcI n=13 Tax=Proteobact...   245   7e-64
UniRef50_B7KJ26 CRISPR-associated protein Cas5 family n=1 Tax=Cy...   202   6e-51
UniRef50_D1NTI1 CRISPR-associated protein Cas5 n=1 Tax=Bifidobac...   202   7e-51
UniRef50_Q12YA8 CRISPR-associated protein, CT1976-like n=1 Tax=M...   195   1e-48
UniRef50_Q314I4 CRISPR-associated protein, CT1976 n=1 Tax=Desulf...   190   4e-47
UniRef50_D1CGD4 CRISPR-associated protein Cas5 family n=6 Tax=Ba...   188   9e-47
UniRef50_A3EQA4 CRISPR-ssociated protein, Cas5 n=3 Tax=Bacteria ...   186   6e-46
UniRef50_A1ARH6 CRISPR-associated protein, Cas5e family n=2 Tax=...   184   3e-45
UniRef50_B0TDU1 Crispr-associated protein cas5 n=1 Tax=Heliobact...   182   6e-45
UniRef50_B8HWH8 CRISPR-associated protein Cas5 family n=1 Tax=Cy...   182   1e-44
UniRef50_C2BET8 CRISPR-associated protein n=2 Tax=Firmicutes Rep...   182   1e-44
UniRef50_Q0W584 Putative uncharacterized protein n=1 Tax=uncultu...   181   1e-44
UniRef50_Q04QB7 Putative uncharacterized protein n=2 Tax=Leptosp...   180   4e-44
UniRef50_A6W168 CRISPR-associated protein Cas5 family n=6 Tax=Ga...   179   5e-44
UniRef50_D0Y918 CRISPR-associated protein Cas5 family n=2 Tax=De...   177   2e-43
UniRef50_B4S8P8 CRISPR-associated protein Cas5 family n=8 Tax=Ba...   177   2e-43
UniRef50_D0WFC8 CRISPR-associated protein Cas5 n=1 Tax=Slackia e...   177   2e-43
UniRef50_Q5YRB6 Putative uncharacterized protein n=1 Tax=Nocardi...   177   3e-43
UniRef50_A7BA63 Putative uncharacterized protein n=1 Tax=Actinom...   177   3e-43
UniRef50_C9M2Y8 CRISPR-associated protein n=1 Tax=Lactobacillus ...   175   8e-43
UniRef50_A5GBK2 CRISPR-associated protein Cas5 family n=2 Tax=De...   175   1e-42
UniRef50_D2RB02 CRISPR system CASCADE complex protein CasD n=3 T...   175   1e-42
UniRef50_A8SDR7 Putative uncharacterized protein n=1 Tax=Faecali...   173   4e-42
UniRef50_B1VIY0 CRISPR-associated protein n=9 Tax=Actinomycetale...   173   4e-42
UniRef50_B0S4B6 Putative uncharacterized protein n=1 Tax=Finegol...   172   5e-42
UniRef50_UPI0001AF1D4C CRISPR-associated protein, CT1976 n=1 Tax...   172   6e-42
UniRef50_Q1R114 CRISPR-associated protein, CT1976 n=1 Tax=Chromo...   172   7e-42
UniRef50_Q47PI7 CRISPR-associated protein, Cas5e family n=12 Tax...   172   7e-42
UniRef50_Q1EQS9 CRISPR-associated protein n=3 Tax=Streptomyces R...   172   8e-42
UniRef50_A8M404 CRISPR-associated protein Cas5 family n=1 Tax=Sa...   172   9e-42
UniRef50_Q2JWC5 CRISPR-associated protein Cas5, Ecoli subtype n=...   172   1e-41
UniRef50_A1SV73 CRISPR-associated protein, Cas5e family n=2 Tax=...   171   1e-41
UniRef50_A5UR14 CRISPR-associated protein, Cas5e family n=1 Tax=...   171   2e-41
UniRef50_B2GBJ9 Putative uncharacterized protein n=1 Tax=Lactoba...   171   2e-41
UniRef50_C7MQD6 CRISPR-associated protein Cas5 n=1 Tax=Saccharom...   170   3e-41
UniRef50_C7LYW6 CRISPR-associated protein Cas5 family n=1 Tax=Ac...   169   5e-41
UniRef50_Q03C60 CRISPR-associated protein n=4 Tax=Lactobacillus ...   168   2e-40
UniRef50_A8ZZ17 CRISPR-associated protein Cas5 family n=1 Tax=De...   167   2e-40
UniRef50_D2L2X8 CRISPR-associated protein Cas5 family n=1 Tax=De...   164   1e-39
UniRef50_B8IZA7 CRISPR-associated protein Cas5 family n=1 Tax=De...   163   3e-39
UniRef50_Q2RY19 CRISPR-associated protein, Cas5e family n=1 Tax=...   163   5e-39
UniRef50_C8XAY4 CRISPR-associated protein Cas5 family n=2 Tax=Ac...   162   1e-38
UniRef50_A8LYZ7 CRISPR-associated protein Cas5 family n=2 Tax=Ac...   161   2e-38
UniRef50_D1A6Q5 CRISPR-associated protein Cas5 family n=2 Tax=Ac...   160   2e-38
UniRef50_Q2JH27 CRISPR-associated protein, CT1976 n=6 Tax=Actino...   160   3e-38
UniRef50_D1CAJ0 CRISPR-associated protein Cas5 family n=1 Tax=Sp...   160   3e-38
UniRef50_C5SD48 CRISPR-associated protein Cas5 family n=1 Tax=Al...   160   4e-38
UniRef50_C9M9R7 CRISPR-associated protein Cas5, Ecoli subtype n=...   159   1e-37
UniRef50_C7MTB0 CRISPR-associated protein Cas5 n=1 Tax=Saccharom...   158   1e-37
UniRef50_B3E5U9 CRISPR-associated protein Cas5 family n=2 Tax=De...   156   4e-37
UniRef50_B8GIV3 CRISPR-associated protein Cas5 family n=1 Tax=Me...   156   6e-37
UniRef50_Q0AA33 CRISPR-associated protein Cas5 family n=2 Tax=Ga...   156   6e-37
UniRef50_D0MET6 CRISPR-associated protein Cas5 family n=1 Tax=Rh...   155   1e-36
UniRef50_Q1J367 CRISPR-associated protein, CT1976 n=1 Tax=Deinoc...   154   3e-36
UniRef50_B4UE71 CRISPR-associated protein Cas5 family n=2 Tax=An...   154   3e-36
UniRef50_Q2FNU0 CRISPR-associated protein, CT1976 n=1 Tax=Methan...   151   2e-35
UniRef50_D1Y486 Crispr-associated protein Cas5 n=1 Tax=Pyramidob...   151   2e-35
UniRef50_Q0BSC7 Putative uncharacterized protein n=1 Tax=Granuli...   151   2e-35
UniRef50_B8FDI0 CRISPR-associated protein Cas5 family n=3 Tax=Ba...   148   1e-34
UniRef50_A9HLC6 CRISPR-associated protein Cas5 family n=11 Tax=A...   145   1e-33
UniRef50_B6B783 CRISPR-associated protein Cas5, Ecoli subtype n=...   144   2e-33
UniRef50_B4TTX2 CRISPR-associated protein Cas5 n=15 Tax=Enteroba...   141   2e-32
UniRef50_UPI0001B51C2B CRISPR-associated Cas5 family protein n=1...   139   5e-32
UniRef50_C5V9N1 CRISPR-associated protein Cas5 n=1 Tax=Corynebac...   137   2e-31
UniRef50_Q3AA65 CRISPR-associated protein Cas5, Hmari subtype n=...   137   2e-31
UniRef50_B5GY62 Crispr-associated protein (Fragment) n=1 Tax=Str...   134   2e-30
UniRef50_B8IMR2 CRISPR-associated protein Cas5 family n=1 Tax=Me...   133   4e-30
UniRef50_B5F422 CRISPR-associated protein Cas5 n=59 Tax=Enteroba...   133   5e-30
UniRef50_B0K553 CRISPR-associated protein Cas5, Hmari subtype n=...   131   2e-29
UniRef50_A7ZDW7 Crispr-associated protein Cas5 n=3 Tax=Campyloba...   130   3e-29
UniRef50_C2KP44 Putative uncharacterized protein n=1 Tax=Mobilun...   129   6e-29
UniRef50_B6XT64 Putative uncharacterized protein n=2 Tax=Bifidob...   129   6e-29
UniRef50_Q2RXJ5 CRISPR-associated protein, Cas5e family n=5 Tax=...   126   5e-28
UniRef50_Q6NEQ9 Putative uncharacterized protein n=1 Tax=Coryneb...   123   3e-27
UniRef50_A5D0Y3 Putative uncharacterized protein n=1 Tax=Pelotom...   123   4e-27
UniRef50_B8IJS9 CRISPR-associated protein Cas5 family n=1 Tax=Me...   123   4e-27
UniRef50_B6IWM3 CRISPR-associated protein, CT1976 family n=1 Tax...   123   4e-27
UniRef50_C0W6U0 CRISPR-associated Cas5 family protein n=1 Tax=Ac...   122   6e-27
UniRef50_C2GEY8 CRISPR-associated protein n=1 Tax=Corynebacteriu...   121   2e-26
UniRef50_Q1AZD3 CRISPR-associated protein, Cas5h family n=1 Tax=...   120   3e-26
UniRef50_C8PE23 CRISPR-associated protein Cas5 n=1 Tax=Campyloba...   115   1e-24
UniRef50_A7HLK6 CRISPR-associated protein Cas5, Hmari subtype n=...   114   2e-24
UniRef50_B5YBH8 CRISPR-associated protein Cas5, Hmari subtype n=...   112   7e-24
UniRef50_D1N0K0 Putative uncharacterized protein n=1 Tax=Victiva...   108   1e-22
UniRef50_O27159 Putative uncharacterized protein n=1 Tax=Methano...   106   8e-22
UniRef50_B9MPU1 CRISPR-associated protein Cas5, Hmari subtype n=...   105   9e-22
UniRef50_C7P9L3 CRISPR-associated protein Cas5 n=2 Tax=Methanoca...   105   9e-22
UniRef50_C7NNV3 CRISPR-associated protein Cas5, Hmari subtype n=...   104   2e-21
UniRef50_D1CHV1 CRISPR-associated protein Cas5 n=1 Tax=Thermobac...   104   3e-21
UniRef50_Q2NH81 Putative uncharacterized protein n=1 Tax=Methano...   103   4e-21
UniRef50_B5IGN1 CRISPR-associated protein Cas5 n=1 Tax=Acidulipr...   100   5e-20
UniRef50_UPI0000F51765 hypothetical protein Faci_00030 n=1 Tax=F...    97   3e-19
UniRef50_A3XI99 Putative uncharacterized protein n=1 Tax=Leeuwen...    97   4e-19
UniRef50_C1DUR1 Crispr-associated protein Cas5, hmari subtype n=...    96   7e-19
UniRef50_B7R550 CRISPR-associated protein Cas5 n=1 Tax=Thermococ...    96   7e-19
UniRef50_A3DKB9 CRISPR-associated protein Cas5, Hmari subtype n=...    95   1e-18
UniRef50_C6QNG6 CRISPR-associated protein Cas5, Hmari subtype n=...    95   1e-18
UniRef50_A4J1X9 CRISPR-associated protein Cas5, Hmari subtype n=...    95   2e-18
UniRef50_A0LM54 Putative uncharacterized protein n=1 Tax=Syntrop...    95   2e-18
UniRef50_O57910 Putative uncharacterized protein PH0171 n=1 Tax=...    94   3e-18
UniRef50_B1LAM2 CRISPR-associated protein Cas5, Hmari subtype n=...    93   5e-18
UniRef50_B8CYA3 CRISPR-associated protein Cas5 n=1 Tax=Halotherm...    93   7e-18
UniRef50_A7BQN4 Protein containing DUF522 n=1 Tax=Beggiatoa sp. ...    93   8e-18
UniRef50_A3DHS3 CRISPR-associated protein Cas5 n=3 Tax=Clostridi...    92   1e-17
UniRef50_C9RCY2 CRISPR-associated protein Cas5, Hmari subtype n=...    92   2e-17
UniRef50_D0MJ68 CRISPR-associated protein Cas5 n=1 Tax=Rhodother...    90   5e-17
UniRef50_D1B1G1 CRISPR-associated protein Cas5 n=1 Tax=Sulfurosp...    90   5e-17
UniRef50_B1B9K0 Crispr-associated protein Cas5, tneap subtype n=...    89   1e-16
UniRef50_Q8PZD2 Putative uncharacterized protein n=1 Tax=Methano...    85   1e-15
UniRef50_D2QT47 CRISPR-associated protein Cas5 n=1 Tax=Spirosoma...    85   2e-15
UniRef50_Q3M7D6 Fruiting body developmental protein S-like prote...    83   7e-15
UniRef50_C8VZL1 CRISPR-associated protein Cas5 n=1 Tax=Desulfoto...    81   2e-14
UniRef50_B1I4M5 CRISPR-associated protein Cas5 family n=1 Tax=Ca...    79   1e-13
UniRef50_B1I5P1 CRISPR-associated protein Cas5 n=2 Tax=Clostridi...    78   2e-13
UniRef50_D1A6P6 Metal dependent phosphohydrolase n=1 Tax=Thermom...    74   3e-12

Sequences not found previously or not previously below threshold:

UniRef50_A8F3P0 CRISPR-associated protein Cas5, Hmari subtype n=...    86   9e-16
UniRef50_C5CFB1 CRISPR-associated protein Cas5, Hmari subtype n=...    82   1e-14
UniRef50_B0VIK7 Putative uncharacterized protein n=1 Tax=Candida...    79   1e-13
UniRef50_A0B6V6 CRISPR-associated protein Cas5, Hmari subtype n=...    77   5e-13
UniRef50_UPI0000F51712 CRISPR-associated Cas5 family Hmari subty...    76   7e-13
UniRef50_A6UVX6 CRISPR-associated protein Cas5, Hmari subtype n=...    76   1e-12
UniRef50_A1ZHZ1 Crispr-associated protein Cas5, hmari subtype n=...    75   2e-12
UniRef50_C5D4M6 CRISPR-associated protein Cas5, Hmari subtype n=...    75   2e-12
UniRef50_A9BGY6 CRISPR-associated protein Cas5, Hmari subtype n=...    74   4e-12
UniRef50_A8UUT1 Putative uncharacterized protein n=1 Tax=Hydroge...    74   4e-12
UniRef50_A4XGC7 CRISPR-associated protein Cas5 family n=1 Tax=Ca...    72   2e-11
UniRef50_UPI00016C61FD CRISPR-associated protein Cas5, hmari sub...    70   4e-11
UniRef50_B9D004 Crispr-associated protein Cas5 n=1 Tax=Campyloba...    70   7e-11
UniRef50_B8DZH7 CRISPR-associated protein Cas5, Hmari subtype n=...    69   1e-10
UniRef50_B9LWL0 CRISPR-associated protein Cas5, Hmari subtype n=...    69   1e-10
UniRef50_C9RW51 CRISPR-associated protein Cas5, Hmari subtype n=...    69   2e-10
UniRef50_B0ABR7 Putative uncharacterized protein n=1 Tax=Clostri...    69   2e-10
UniRef50_A4FXZ5 CRISPR-associated protein Cas5 n=1 Tax=Methanoco...    68   2e-10
UniRef50_B8FSG3 CRISPR-associated protein Cas5 n=4 Tax=Firmicute...    68   3e-10
UniRef50_C1TQC8 CRISPR-associated protein Cas5, Hmari subtype n=...    67   3e-10
UniRef50_Q2NFS3 Putative uncharacterized protein n=1 Tax=Methano...    67   6e-10
UniRef50_A7VC52 Putative uncharacterized protein n=1 Tax=Clostri...    65   2e-09
UniRef50_Q0AW00 CRISPR-associated protein, Cas5h family n=2 Tax=...    65   2e-09
UniRef50_C9M4F0 Putative uncharacterized protein n=1 Tax=Lactoba...    64   4e-09
UniRef50_B1L2N4 Crispr-associated protein Cas5, hmari subtype n=...    64   4e-09
UniRef50_A4XM40 CRISPR-associated protein Cas5 family n=3 Tax=Cl...    64   4e-09
UniRef50_B7AS04 Putative uncharacterized protein n=1 Tax=Bactero...    64   5e-09
UniRef50_C9XLN6 Putative uncharacterized protein n=6 Tax=Clostri...    63   7e-09
UniRef50_Q12WX6 CRISPR-associated protein Cas5, Hmari subtype n=...    63   8e-09
UniRef50_A1ZVP9 Crispr-associated protein Cas5, tneap subtype n=...    63   8e-09
UniRef50_C9L3W3 CRISPR-associated protein Cas5, Tneap subtype n=...    62   1e-08
UniRef50_A6TQ83 CRISPR-associated protein Cas5 family n=9 Tax=Ba...    62   1e-08
UniRef50_A1HND7 CRISPR-associated protein Cas5 family n=1 Tax=Th...    62   2e-08
UniRef50_A5ILM6 CRISPR-associated protein Cas5 family n=3 Tax=Th...    61   3e-08
UniRef50_B8DAB1 Crispr-associated protein Cas5, tneap subtype n=...    60   7e-08
UniRef50_B5YL08 CRISPR-associated protein Cas5 n=1 Tax=Thermodes...    59   2e-07
UniRef50_A9WFZ3 CRISPR-associated protein Cas5 family n=6 Tax=Ch...    58   3e-07
UniRef50_C5VUI7 Crispr-associated protein Cas5, hmari subtype n=...    57   5e-07
UniRef50_B3EG03 CRISPR-associated protein Cas5 family n=4 Tax=ce...    57   6e-07
UniRef50_O66696 Putative uncharacterized protein n=2 Tax=Aquific...    56   9e-07
UniRef50_D1QSA9 CRISPR-associated protein Cas5, Tneap subtype n=...    56   9e-07
UniRef50_Q0ATZ7 CRISPR-associated protein, Cas5h family n=1 Tax=...    56   1e-06
UniRef50_C9XPZ9 Putative uncharacterized protein n=5 Tax=Clostri...    55   1e-06
UniRef50_B1BR50 Crispr-associated protein Cas5 n=1 Tax=Clostridi...    55   1e-06
UniRef50_Q2RHQ8 Putative uncharacterized protein n=1 Tax=Moorell...    55   1e-06
UniRef50_B5YIV3 CRISPR-associated protein Cas5 n=1 Tax=Thermodes...    55   2e-06
UniRef50_B7GIV5 CRISPR system related protein, RAMP superfamily ...    55   2e-06
UniRef50_C1QDM0 CRISPR-associated protein Cas5 n=1 Tax=Brachyspi...    55   2e-06
UniRef50_C0QHV7 Putative CRISPR-associated protein Cas5 n=1 Tax=...    54   3e-06
UniRef50_C3HBA5 Putative uncharacterized protein n=2 Tax=Bacillu...    54   5e-06
UniRef50_A7GQ89 CRISPR-associated protein Cas5 family n=1 Tax=Ba...    53   8e-06
UniRef50_Q1Q0Z9 Putative uncharacterized protein n=1 Tax=Candida...    52   1e-05
UniRef50_A0RNQ4 Crispr-associated protein Cas5, hmari subtype n=...    52   2e-05
UniRef50_B9L1B8 CRISPR-associated protein Cas5, Tneap subtype n=...    52   2e-05
UniRef50_C5U6V3 CRISPR-associated protein Cas5 family n=6 Tax=Eu...    52   2e-05
UniRef50_UPI0001693F6C hypothetical protein Plarl_07470 n=1 Tax=...    52   2e-05
UniRef50_C8K6I7 Crispr-associated protein cas5 n=1 Tax=Listeria ...    52   2e-05
UniRef50_A6DAF2 Putative uncharacterized protein n=1 Tax=Caminib...    51   3e-05
UniRef50_A8TI38 CRISPR-associated protein Cas5 family n=1 Tax=Me...    51   3e-05
UniRef50_B7JW17 CRISPR-associated protein DevS n=2 Tax=Cyanobact...    51   4e-05
UniRef50_A6UNR9 CRISPR-associated protein Cas5, Hmari subtype n=...    50   5e-05
UniRef50_C4IBN8 CRISPR-associated protein Cas5 n=5 Tax=Bacteria ...    50   6e-05
UniRef50_B4U1Q4 CRISPR-associated protein Cas5, Dvulg subtype n=...    48   2e-04
UniRef50_C1DUL8 Crispr-associated protein Cas5, tneap subtype n=...    48   2e-04
UniRef50_C2HJA9 Putative uncharacterized protein n=1 Tax=Finegol...    47   3e-04
UniRef50_A5N0X1 Putative uncharacterized protein n=2 Tax=Clostri...    46   0.001
UniRef50_C6A4J5 Putative uncharacterized protein n=1 Tax=Thermoc...    45   0.001
UniRef50_C9XQW2 Crispr-associated protein cas5 family n=2 Tax=Cl...    45   0.002
UniRef50_Q8F1E3 Fruiting body developmental protein S-like prote...    45   0.002
UniRef50_A5TU43 Putative uncharacterized protein n=3 Tax=Fusobac...    42   0.011
UniRef50_B5YAX9 CRISPR-associated protein Cas5, Tneap subtype n=...    42   0.012
UniRef50_B6WA84 Putative uncharacterized protein n=2 Tax=Anaeroc...    42   0.014
UniRef50_A9GDF4 Fruiting body developmental protein S n=2 Tax=Ba...    40   0.041
UniRef50_C0D371 Putative uncharacterized protein n=1 Tax=Clostri...    40   0.081
UniRef50_Q8TYH7 Coenzyme F420-reducing hydrogenase, beta subunit...    39   0.092

>UniRef50_Q46898 Uncharacterized protein ygcI n=13 Tax=Proteobacteria
           RepID=YGCI_ECOLI
          Length = 224

 Score =  245 bits (626), Expect = 7e-64,   Method: Composition-based stats.
 Identities = 224/224 (100%), Positives = 224/224 (100%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES
Sbjct: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL
Sbjct: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180
           WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD
Sbjct: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180

Query: 181 IYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVSQ 224
           IYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVSQ
Sbjct: 181 IYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVSQ 224


>UniRef50_B7KJ26 CRISPR-associated protein Cas5 family n=1 Tax=Cyanothece sp. PCC
           7424 RepID=B7KJ26_CYAP7
          Length = 215

 Score =  202 bits (515), Expect = 6e-51,   Method: Composition-based stats.
 Identities = 67/228 (29%), Positives = 112/228 (49%), Gaps = 17/228 (7%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M   L+LRLAGP+Q+WG+ +    R T   PT+SG++GL+ A +GI RD+   L  L++ 
Sbjct: 1   MMKTLLLRLAGPLQSWGRGSRFDFRDTDTIPTKSGVIGLVAAAMGINRDNQVELAKLAQ- 59

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           ++  V  ++            + DYHTV+G      G      IQ++R+YLC+A F V L
Sbjct: 60  LRMGVCVEK--------EGKLVVDYHTVIGTIHA-DGKPHKAPIQSYRQYLCNAEFLVGL 110

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNY--EPVG 178
             +     +++E+E  +  P++  +LGR++CP + P+F+     +  + AL  Y    + 
Sbjct: 111 ESS--EYHLLNEIEHYLCFPKWELFLGRKACPPSKPIFVDLLT-NSLEDALYQYAISHLK 167

Query: 179 GDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIK--GGMDVSQ 224
              Y     +         D P+    R F++R     K     DVS+
Sbjct: 168 KGTYRLLIESKEPTGALRLDVPIDFKKRIFSARTVITPKPLEVSDVSE 215


>UniRef50_D1NTI1 CRISPR-associated protein Cas5 n=1 Tax=Bifidobacterium gallicum DSM
           20093 RepID=D1NTI1_9BIFI
          Length = 250

 Score =  202 bits (514), Expect = 7e-51,   Method: Composition-based stats.
 Identities = 66/232 (28%), Positives = 101/232 (43%), Gaps = 28/232 (12%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            S LILRLAGPMQ+WG  +    R T   PT+S ++GLL +  G +R+D  S++ L   +
Sbjct: 1   MSVLILRLAGPMQSWGDSSRFNRRETRTEPTKSAVIGLLASAQGRRRED--SIEDLL-GL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +F VR D+            +RD+ T         G  S     T R YL DA F VA+ 
Sbjct: 58  RFGVRSDQ--------PGRIMRDFQTEKSIARKKSGEFSLTMPLTHRYYLADAKFLVAIE 109

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                  ++  L+ A+  P++  +LGRRSCP   P+ LG    ++ ++AL     +    
Sbjct: 110 ---GERSLLESLDAALRNPQWPLFLGRRSCPPASPVSLGVKDYANVEEALDKEPWIASPW 166

Query: 182 YSEE------------SVTGHHLKFTARDEPMITL--PRQFASREWYVIKGG 219
           Y ++            +V          D P+      R++A R        
Sbjct: 167 YRKKVHDSKRLQVVVDAVENGETTGQQSDMPLSFSQKHRRYAQRPVRRYFVD 218


>UniRef50_Q12YA8 CRISPR-associated protein, CT1976-like n=1 Tax=Methanococcoides
           burtonii DSM 6242 RepID=Q12YA8_METBU
          Length = 244

 Score =  195 bits (495), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 62/251 (24%), Positives = 100/251 (39%), Gaps = 38/251 (15%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M+ YLI RL GPM +WG       RPT   P++S + GL+ A LGI+RD+      LS +
Sbjct: 1   MKEYLIFRLYGPMASWGDIAVGQHRPTYDHPSKSAIFGLIAAALGIRRDEEERHLELSNA 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAR---------------EDYRGLKSHETIQ 105
             +              +   LRDYHT                    E     +   T+ 
Sbjct: 61  YSYGTLI--------NSAGKLLRDYHTSQVPSAGTGRNRKTFATRKDELAVPKEELNTVL 112

Query: 106 TWREYLCDASFTVALWLTPH-ATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQA 164
           + R+Y CD  +TV L          +  L  ++ +P +  YLGR+SCPL  P+      A
Sbjct: 113 STRDYYCDGVYTVILSCKTDTPPYSLELLGNSLKEPSFCLYLGRKSCPLALPINPKIVSA 172

Query: 165 SDPQKALLNYEPVGGDIYSEESVTGHHL--------------KFTARDEPMITLPRQFAS 210
           S+ ++AL + +P    +  +  +   +                 +  D+ +     QF+ 
Sbjct: 173 SNIKEALQSVDPGEEGLVKKIEMKSPYRLYWDDPKESMTCEHTISRYDKLLSRKRWQFSK 232

Query: 211 REWYVIKGGMD 221
           R  Y     ++
Sbjct: 233 RNEYYAMVSLE 243


>UniRef50_Q314I4 CRISPR-associated protein, CT1976 n=1 Tax=Desulfovibrio
           desulfuricans subsp. desulfuricans str. G20
           RepID=Q314I4_DESDG
          Length = 245

 Score =  190 bits (482), Expect = 4e-47,   Method: Composition-based stats.
 Identities = 76/238 (31%), Positives = 106/238 (44%), Gaps = 30/238 (12%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M  YL  ++ GP+QA+G       RPT   PTRS +LG+L A +GI+RD+ + L  L + 
Sbjct: 1   MAQYLTFQIYGPLQAYGTVAVGEIRPTSTMPTRSAVLGILAAAIGIRRDEETRLAELRDG 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGA----------REDYRGLKSHETIQTWREY 110
            + AVR D             + DYHT+             R D   L    TI + REY
Sbjct: 61  YRVAVRED--------APGKVMLDYHTIQTPGARGKRQLHCRRDELLLTEPNTILSRREY 112

Query: 111 LCDASFTVALWLTPHA-TMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQK 169
           L DA FTV LW   H     + E+ +A+  PR+T  LGR+SCP   P        + PQ+
Sbjct: 113 LMDALFTVCLWQANHTVPYSLQEIARALRSPRWTIGLGRKSCPPALPFAPKITDHTTPQE 172

Query: 170 ALLNYE-----------PVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVI 216
           A+  Y            P    +  +        + T RD P+    RQFA R+   +
Sbjct: 173 AVAAYPADKLVSAGLRSPQVMRMLLDTEGPHTDTETTVRDVPLHHGRRQFAERKVREL 230


>UniRef50_D1CGD4 CRISPR-associated protein Cas5 family n=6 Tax=Bacteria
           RepID=D1CGD4_THET1
          Length = 230

 Score =  188 bits (478), Expect = 9e-47,   Method: Composition-based stats.
 Identities = 66/228 (28%), Positives = 104/228 (45%), Gaps = 25/228 (10%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L++RL+GPMQ+WG  +    R TGR P++SG++GL+ A LG  R   + +  L   +
Sbjct: 1   MPTLLMRLSGPMQSWGTQSRFTVRDTGREPSKSGVIGLICAALGRPRT--APVDDL-VRL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSH-----ETIQTWREYLCDASF 116
           +  VR D             +RDYHT  GA    R   +        +Q+ R YL DASF
Sbjct: 58  RMGVRVDR--------EGIVMRDYHTAGGAPAGERYGVATVTGDQRPVQSSRYYLADASF 109

Query: 117 TVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGT-------CQASDPQK 169
            VAL        ++ ++++A+  PR+  +LGR+SC  + P+ L          +  D + 
Sbjct: 110 LVALEGGEEDRPLLEQIDEALRAPRWQLFLGRKSCVPSEPIHLPKEPPLGPPIREEDLRT 169

Query: 170 ALLNYEPVGGDIYSEESVTGHHLKFTARDEPMIT--LPRQFASREWYV 215
           AL++Y    G             +    D P+      RQ+A+R    
Sbjct: 170 ALISYPWPEGAHRLRFVFEDPEGEELRNDVPISFEIGNRQYAARFVRT 217


>UniRef50_A3EQA4 CRISPR-ssociated protein, Cas5 n=3 Tax=Bacteria RepID=A3EQA4_9BACT
          Length = 227

 Score =  186 bits (472), Expect = 6e-46,   Method: Composition-based stats.
 Identities = 60/227 (26%), Positives = 96/227 (42%), Gaps = 22/227 (9%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L++RL  PMQ+WG  +    R TG+ P++SG++GLL A LGI R++   L+ L+  +
Sbjct: 1   MPTLLIRLVSPMQSWGTSSRFDQRDTGKEPSKSGVIGLLAAALGIDRNNWDDLEPLA-GL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
              VR D              RDY T           K H T  T+REYL DA F V   
Sbjct: 60  SMGVRHDR--------PGIPRRDYQTASKII-SADHSKIHPTAVTYREYLADAVFLVGFE 110

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQ-KALLNYEPVGGD 180
                  ++ ++  A+  P +  +LGR+S   + P+++     + P  +AL ++  +   
Sbjct: 111 SA--EVSLLEKINSALKNPVWPLFLGRKSYVPSEPIWIENGLKNVPLREALEHFPWIACR 168

Query: 181 IYSEESVT--------GHHLKFTARDEPM-ITLPRQFASREWYVIKG 218
             +E                     D+P+     R+F SR       
Sbjct: 169 RRNERLPEKLVITFESEDGTGVLKMDQPLSSFAKRRFGSRFVRSEWI 215


>UniRef50_A1ARH6 CRISPR-associated protein, Cas5e family n=2 Tax=Bacteria
           RepID=A1ARH6_PELPD
          Length = 232

 Score =  184 bits (466), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 59/233 (25%), Positives = 92/233 (39%), Gaps = 28/233 (12%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L+LRL GPMQ+WG  +    R TG+ P++SG++GLL A LGI R++   L+ L+  +
Sbjct: 1   MPTLLLRLVGPMQSWGTTSRFDQRDTGKEPSKSGVVGLLAAALGIDRENWVDLEPLT-CL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVL-----GAREDYRGLKSHETIQTWREYLCDASF 116
              VR D              RDY T          +          + + R YL DA+F
Sbjct: 60  AMGVRHDR--------PGVPKRDYQTAGCASTDTIIKADGTQAKGGGVVSQRFYLADAAF 111

Query: 117 TVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFL--GTCQASDPQKALLNY 174
            V L        ++  +  A+  P +T  LGR+S   +  +++  G   A    + L  Y
Sbjct: 112 LVGLEC--DDNCLLERIHVALHNPFWTLALGRKSYVPSESIWIVDGVRDAP-LLETLKRY 168

Query: 175 EPVGGDIYSEESVT--------GHHLKFTARDEPM-ITLPRQFASREWYVIKG 218
             +      EE                    D+P+     R+F +R       
Sbjct: 169 PWIASSRSREEPPERLLVSIESDDGAGVLKMDQPLSSFAERRFGARFVRSEWI 221


>UniRef50_B0TDU1 Crispr-associated protein cas5 n=1 Tax=Heliobacterium modesticaldum
           Ice1 RepID=B0TDU1_HELMI
          Length = 230

 Score =  182 bits (463), Expect = 6e-45,   Method: Composition-based stats.
 Identities = 64/229 (27%), Positives = 100/229 (43%), Gaps = 23/229 (10%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
            L LRL GP+Q+WG  +    R +   PT+SG++GLLG  LG  R+D   L++L  +++ 
Sbjct: 5   ILALRLEGPLQSWGSRSRWDYRDSALEPTKSGIIGLLGCALGWSRNDK-RLESLDAALRL 63

Query: 64  AVRCDELILDDRRVSVTGLRDYHTVLGAR-----EDYRGLKSHETIQTWREYLCDASFTV 118
            VR D+          T L D+HTV G       +  +      T+ + R YL +ASF  
Sbjct: 64  TVRIDK--------PGTPLIDFHTVQGYLLMAEGKQKKSGNDMYTVVSRRVYLQEASFLA 115

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQAS--DPQKALLNYEP 176
            L         + + +KA+  P +  +LGR+SCP   PLF    +    D  +A+ +   
Sbjct: 116 LLT---GEQGALHQCKKALNDPVWPVFLGRKSCPPARPLFDSFYEGDFRDVLEAMRSIPW 172

Query: 177 ----VGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMD 221
                 G I     +     +   +D   I   R +  R   V    +D
Sbjct: 173 SSAPAAGPIRLRYVMEDEGGREWRQDVLRINGARMYGRRRVSVGWVDLD 221


>UniRef50_B8HWH8 CRISPR-associated protein Cas5 family n=1 Tax=Cyanothece sp. PCC
           7425 RepID=B8HWH8_CYAP4
          Length = 216

 Score =  182 bits (461), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 52/218 (23%), Positives = 89/218 (40%), Gaps = 22/218 (10%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L+LR+  PM +WG  +    R + R PT+S ++GLL A LG  R    ++  L+ ++
Sbjct: 1   MPTLLLRMRAPMMSWGDHSRFTIRDSRREPTKSAVIGLLCAALGRPR--WEAVADLT-AL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +  VR ++  L           DYHTV  +           T+ + R Y+ DA + V L 
Sbjct: 58  KMGVRINQEGLVQC--------DYHTVQDS--IKSSGSKGNTVISHRYYIADADYLVGLE 107

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
            +      +  L+ A+  P +  Y GR+S   + P+ L         +AL +   +   +
Sbjct: 108 GS--DRHFLESLDSALQSPIWQVYFGRKSFVPSCPVALHVSDQP-LAEALKHRITLSKTM 164

Query: 182 YSEES------VTGHHLKFTARDEPMITLPRQFASREW 213
             +        +         +D P+    R F SR  
Sbjct: 165 AHKLPNRLRCVLEVPDSLDVRQDVPLDWQKRHFGSRCV 202


>UniRef50_C2BET8 CRISPR-associated protein n=2 Tax=Firmicutes RepID=C2BET8_9FIRM
          Length = 244

 Score =  182 bits (461), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 62/232 (26%), Positives = 102/232 (43%), Gaps = 29/232 (12%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
             ++L+L GPMQ+WG  +   TR +  +P++SG++G++ A  G +RD+   +Q L++ + 
Sbjct: 5   KTILLKLTGPMQSWGTSSRFETRTSDYYPSKSGVIGIIAASFGYERDEDEKIQKLND-LD 63

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWL 122
           FAVR D+             +DYH     R+     +   T  T R Y+ DA F VA+  
Sbjct: 64  FAVRVDQ--------EGVLKKDYHIA---RKVKPNGELERTYVTNRYYMEDAVFVVAI-- 110

Query: 123 TPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDIY 182
           +      + E+ + +  P + P++GRRSCPL     LGT +   P +AL N +    D +
Sbjct: 111 SHEDDKWMEEILQGLKYPYFQPFMGRRSCPLPARFILGTNE-EGPIEALENLDWQAADWF 169

Query: 183 SEE--------------SVTGHHLKFTARDEPMITLPRQFASREWYVIKGGM 220
            ++                   H     R        R+F  R        M
Sbjct: 170 KKKNKNYRADIYADKDLLPENSHTIRNDRVVSFSQKERKFGPRFEARSSLVM 221


>UniRef50_Q0W584 Putative uncharacterized protein n=1 Tax=uncultured methanogenic
           archaeon RC-I RepID=Q0W584_UNCMA
          Length = 227

 Score =  181 bits (460), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 60/218 (27%), Positives = 90/218 (41%), Gaps = 20/218 (9%)

Query: 10  AGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDE 69
            GPMQ+WG       R TG  PT+SG++GLLG  LG  R D      L   ++  +R + 
Sbjct: 12  EGPMQSWGLKARWDIRDTGDEPTKSGIIGLLGCALGYARKDPRLTDELDSQLRIGIRVEC 71

Query: 70  LILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPHATMV 129
                        RDYHTV G      G     TI ++R+YL DA+F V L        +
Sbjct: 72  --------PGEIARDYHTVSGELRTAEGKLRETTIVSFRDYLQDAAFLVVLEGPGE---L 120

Query: 130 ISELEKAVLKPRYTPYLGRRSCPLTHPLFLGT-CQASDPQKALLNYEPVGGDIYSEES-- 186
           ++ +  A+  P +  YLGR+SCP T P+F       +    AL  +    G + + ++  
Sbjct: 121 LTRISNALKDPVWPIYLGRKSCPPTRPVFETLTTDYASIDDALSRHPWSSGTMEARKAHP 180

Query: 187 ------VTGHHLKFTARDEPMITLPRQFASREWYVIKG 218
                 V      +   D    +  R +  R   +   
Sbjct: 181 KELKCIVEDLSGPYQRTDRMTKSPARMYGIRHVRMSTV 218


>UniRef50_Q04QB7 Putative uncharacterized protein n=2 Tax=Leptospira borgpetersenii
           serovar Hardjo-bovis RepID=Q04QB7_LEPBJ
          Length = 247

 Score =  180 bits (456), Expect = 4e-44,   Method: Composition-based stats.
 Identities = 66/245 (26%), Positives = 95/245 (38%), Gaps = 42/245 (17%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M+ YL+ RL GP+ +WG       RP+  FPT+S ++GL+ A  G  R +   +  L +S
Sbjct: 1   MKDYLVFRLYGPLVSWGNIAVGEYRPSDSFPTKSAIIGLISASFGFDRSEDGKISELVKS 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSH----------ETIQTWREY 110
           V FA +               LRDYHT+       R L +           ETI + R+Y
Sbjct: 61  VFFATKTLN--------PGNLLRDYHTIQSPGNVKRSLLTRKDELLDSEYVETILSSRDY 112

Query: 111 LCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKA 170
             DA + VAL     A   + E+  A+L P +TPYLGR+SC +  P+      +     A
Sbjct: 113 RVDAVYDVALSEKKRAPYSLKEIRNALLSPIHTPYLGRKSCSIALPMCPEILSSDSFPNA 172

Query: 171 LLNYEPVGGDIYSEESVTGHHLKF------------------------TARDEPMITLPR 206
              Y  +    Y                                    + RDE +     
Sbjct: 173 FEEYNKILMKKYESSDYKDPLADLSSKSSAILYLWEDPTELSEKDHTHSRRDEILNRNKW 232

Query: 207 QFASR 211
           QF  R
Sbjct: 233 QFQDR 237


>UniRef50_A6W168 CRISPR-associated protein Cas5 family n=6 Tax=Gammaproteobacteria
           RepID=A6W168_MARMS
          Length = 258

 Score =  179 bits (455), Expect = 5e-44,   Method: Composition-based stats.
 Identities = 78/253 (30%), Positives = 109/253 (43%), Gaps = 43/253 (16%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M+ YL+ RL GPM +WGQP   G R T   PTRS +LGLLGA LGI+RDD   L AL  S
Sbjct: 1   MKDYLVFRLYGPMASWGQPAVGGDRATAIAPTRSAILGLLGAALGIKRDDAQQLDALHSS 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRG-------------LKSHETIQTW 107
           VQ A +        +    + LRDYHT      + +               +   TI + 
Sbjct: 61  VQMATK--------QVTPTSLLRDYHTSQVPSRNNKYVYRTRKNELLDEHKEKLNTILST 112

Query: 108 REYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDP 167
           R+Y CD  + VA+ LT  +   +  L++A++KP Y   LGR+SCPL  PL      +   
Sbjct: 113 RDYRCDGIWIVAVSLTQESLFSLERLKQALIKPVYVLSLGRKSCPLAAPLLPVLLTSVSL 172

Query: 168 QKALL---------NYEPVGGDIYS-------------EESVTGHHLKFTARDEPMITLP 205
           ++AL          +   +                   +E      L     D+P+    
Sbjct: 173 REALDYPFPSIIDNDKPHLDAVWLRPNKLSTYTWEGSVDEFSGETALTTHPWDDPINRDR 232

Query: 206 RQFASREWYVIKG 218
            QF  R  + I  
Sbjct: 233 WQFKQRTMHQITV 245


>UniRef50_D0Y918 CRISPR-associated protein Cas5 family n=2 Tax=Dehalococcoides
           RepID=D0Y918_9CHLR
          Length = 205

 Score =  177 bits (450), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 64/216 (29%), Positives = 105/216 (48%), Gaps = 19/216 (8%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
            L++RL GPMQ+WG  +    R T   PTRSG++GL+ A +GI RD+     A  + ++ 
Sbjct: 6   TLLMRLEGPMQSWGYRSRFDCRDTALEPTRSGVIGLICAAMGIARDED---IARFDGIRM 62

Query: 64  AVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLT 123
            VR D     ++        DYHT L            +T+ ++R+YL DASFTV L  +
Sbjct: 63  GVRVDRDGKVEQ--------DYHTALDV--IKADGSGKDTVVSYRDYLTDASFTVGLESS 112

Query: 124 PHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDIYS 183
                ++ ++ KA++ P++  +LGR++ PLT P      + S+P K     E +     +
Sbjct: 113 --DRNLLEKIAKALVSPQWVLFLGRKAFPLTKPP---IFEFSNPVKPGSLEEHLLCGASA 167

Query: 184 EES-VTGHHLKFTARDEPMITLPRQFASREWYVIKG 218
           +   +     + T  D P+    R+F  R + V   
Sbjct: 168 KRVLLESPDGERTQYDWPLCFGERRFKPRRFTVKYV 203


>UniRef50_B4S8P8 CRISPR-associated protein Cas5 family n=8 Tax=Bacteria
           RepID=B4S8P8_PROA2
          Length = 243

 Score =  177 bits (450), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 55/242 (22%), Positives = 88/242 (36%), Gaps = 26/242 (10%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
           YL+L L  P+Q+WG  +  G R T  FPT+SG+LG+L   LG   +    L+ ++   Q 
Sbjct: 5   YLLLWLEAPLQSWGADSRFGRRGTLEFPTKSGVLGMLCCSLGAGGEQKELLEKMAPLKQS 64

Query: 64  AVRCDELILDDRR-----VSVTGLRDYHTVLGAREDYRGLK--------------SHETI 104
           A+         +           LRD+H V    +D    +              +  + 
Sbjct: 65  AISFCRTSKFRQEEIKKLDREPLLRDFHMVGSGYDDKNPWETLLIPKKSDGTTAVNGGSK 124

Query: 105 QTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQA 164
            T+R YL DA F V + +      +      A+  P +  Y GR+ C  T  ++ G    
Sbjct: 125 ITYRYYLQDAVFAVIMEVPSEKLTLF---ADALENPCWDIYFGRKCCAPTDFIYRGCFNT 181

Query: 165 SDP-QKALLNYEPVGGDIYSEESVTGHHLK--FTARDEPMITLPRQ-FASREWYVIKGGM 220
                   L        +     V G H        D P+    ++ +  R   VI    
Sbjct: 182 ESLAIGKALEIAQEKRLMEDFRVVDGEHEGEAIVLNDVPIQFGEQKLYRERRVTVISCAN 241

Query: 221 DV 222
           + 
Sbjct: 242 EN 243


>UniRef50_D0WFC8 CRISPR-associated protein Cas5 n=1 Tax=Slackia exigua ATCC 700122
           RepID=D0WFC8_9ACTN
          Length = 267

 Score =  177 bits (450), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 63/250 (25%), Positives = 106/250 (42%), Gaps = 43/250 (17%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+L+LA P+Q+WG  +    R T   P++SG++GLL A LG +R+D  S+  L+ ++
Sbjct: 4   MTVLLLKLAAPLQSWGASSRFTERTTRHEPSKSGVIGLLAAALGRRRED--SVDDLA-AL 60

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHET---IQTWREYLCDASFTV 118
           +FAVR D+          + +RD+ T    + D    +         + R+YL DA F  
Sbjct: 61  RFAVRIDQ--------PGSFMRDFQTEHTRKWDSDTRRFVFNESLSLSKRDYLSDAVFVA 112

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVG 178
           AL        +++E  +A+  P +  +LGRRSCP +  ++LG        +AL +     
Sbjct: 113 ALE---GDEDLLAECAEALHHPAFPLFLGRRSCPPSTQVYLGLVDGP-MMEALADIPWQA 168

Query: 179 GDI-----YSEESVTGHHLK------------------FTARDEPMITL--PRQFASREW 213
            +      Y                              T RD P+      R++  R  
Sbjct: 169 TERHWNYAYRFRGDKPKETVELKVVYEATEEQAACTLSETVRDVPLSFSQLKREYGWRTE 228

Query: 214 YVIKGGMDVS 223
             I+  +  S
Sbjct: 229 TTIRMAVKNS 238


>UniRef50_Q5YRB6 Putative uncharacterized protein n=1 Tax=Nocardia farcinica
           RepID=Q5YRB6_NOCFA
          Length = 235

 Score =  177 bits (448), Expect = 3e-43,   Method: Composition-based stats.
 Identities = 63/240 (26%), Positives = 101/240 (42%), Gaps = 36/240 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+LRLA P+Q+WG  +    R T ++P++SG+LGL+ A  G +R D   ++   +++
Sbjct: 1   MTVLLLRLAAPLQSWGVASRFARRETQQYPSKSGILGLIAAARGHRRTD--PIEEALQNL 58

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
            F VR D+            +RD+   L   +  +         + R YL DA F  A+ 
Sbjct: 59  AFGVRVDQ--------PGRLIRDFQVALNIDKTKQF------PLSQRYYLADAVFLAAI- 103

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                  +I  +  A+ +P +  YLGRRSCP+T PL LG  +    + AL   E      
Sbjct: 104 --QGERGLIEGIGNALRRPEFPLYLGRRSCPVTGPLVLGEPRDVTLEHALHETEWQAATW 161

Query: 182 YSE---------------ESVTGHHLKFTARDEPMITLP--RQFASREWYVIKGGMDVSQ 224
           Y                        L+   RD P+   P  R++  R        M  ++
Sbjct: 162 YRRSQHRRVRLPIYRDLLPGDPVELLREQVRDMPLSFDPVRREYGWRTVVEDYTTMLNAE 221


>UniRef50_A7BA63 Putative uncharacterized protein n=1 Tax=Actinomyces odontolyticus
           ATCC 17982 RepID=A7BA63_9ACTO
          Length = 242

 Score =  177 bits (448), Expect = 3e-43,   Method: Composition-based stats.
 Identities = 68/245 (27%), Positives = 103/245 (42%), Gaps = 44/245 (17%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M + L+LRLAGPMQ+WG  +    R T  FPT+S L+GLLGA  G +R D   ++ L+E 
Sbjct: 1   MSAVLVLRLAGPMQSWGADSRFTRRSTEAFPTKSALVGLLGAAQGRRRSD--PIEDLAE- 57

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           +  AVR D+            L D+HT                  + R Y  DA+F   +
Sbjct: 58  LSVAVRVDQ--------PGQLLHDFHTAHRG--------DTSMPLSHRFYRADAAFGAFI 101

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180
                   +I  L +A+++P +  YLGRRSCP T PL L   + S    A+     +   
Sbjct: 102 EGPDD---MIDALAQAIVRPVFPLYLGRRSCPPTLPLRLAVREGSAW-DAVRETPWMAST 157

Query: 181 IYSEESVTGHHLKF-------------------TARDEPMITL--PRQFASREWYVIKGG 219
            Y ++    H ++                    T +D P+      R++  R        
Sbjct: 158 YYQKKQRHDHFVRMRVVADLGIIPPEVEKVAQQTLQDMPISFDSENRKYTLRTVEETYID 217

Query: 220 MDVSQ 224
           ++  Q
Sbjct: 218 LENPQ 222


>UniRef50_C9M2Y8 CRISPR-associated protein n=1 Tax=Lactobacillus helveticus DSM
           20075 RepID=C9M2Y8_LACHE
          Length = 241

 Score =  175 bits (444), Expect = 8e-43,   Method: Composition-based stats.
 Identities = 50/200 (25%), Positives = 85/200 (42%), Gaps = 16/200 (8%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
                +RL  P+Q++G       R +  +P++S ++G++ A LG +RDD   LQ    ++
Sbjct: 1   MKTATIRLTAPLQSYGNQASFNQRTSDNYPSKSAVIGIIAAALGYRRDDARILQ--LNNL 58

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
            FAVR ++            + ++ TV    E  +         T+RE++ DA F VA+ 
Sbjct: 59  LFAVRIEQS--------GNMMTEFQTV----EYQKSSTKTARKLTYREFIQDAVFMVAI- 105

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                   I ++  A+  P++  YLGRRS P   PL + T    +P + L          
Sbjct: 106 -GSDNDHEIEKIVSALKHPKFQLYLGRRSNPPAGPLMIETYDEENPLQVLEKLSWQAEPW 164

Query: 182 YSEESVTGHHLKFTARDEPM 201
           Y +       L     D  +
Sbjct: 165 YQKRLRAPKFLTRIIADAEL 184


>UniRef50_A5GBK2 CRISPR-associated protein Cas5 family n=2 Tax=Deltaproteobacteria
           RepID=A5GBK2_GEOUR
          Length = 231

 Score =  175 bits (444), Expect = 1e-42,   Method: Composition-based stats.
 Identities = 60/221 (27%), Positives = 100/221 (45%), Gaps = 9/221 (4%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE-- 59
           +S+L LRL GP+Q+WG  +    R TG  PT+S + G+  A LG  R      + L    
Sbjct: 10  KSFLALRLEGPLQSWGFDSQYNRRNTGLMPTKSAIAGMCCAALGFLRGCDKEQEFLVAFG 69

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
           +V+            + + V  L+DYHTV   R    G  +++ + T R+YL DA+F V 
Sbjct: 70  AVRMTAIAIPRNGAKKELPVRRLQDYHTVQNTRRA-SGAINNDCVLTHRQYLTDAAFGVL 128

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGG 179
           L      + ++ ++  A+  P +  +LGR++C  T P+  G  +  D    LL  +    
Sbjct: 129 LE---GDSTLLKQIAAALENPVWGVWLGRKTCIPTAPVLAGLRENRDEALKLLLKDKPLE 185

Query: 180 DIYSEESVTG-HHLKFTARDEPMITL--PRQFASREWYVIK 217
               +E V      + +  D P+      R F+ R    ++
Sbjct: 186 SFARQEDVESFADGRDSLPDMPVSFATERRIFSPRRVRTLQ 226


>UniRef50_D2RB02 CRISPR system CASCADE complex protein CasD n=3 Tax=Actinobacteria
           (class) RepID=D2RB02_GARVA
          Length = 291

 Score =  175 bits (443), Expect = 1e-42,   Method: Composition-based stats.
 Identities = 53/187 (28%), Positives = 86/187 (45%), Gaps = 17/187 (9%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQR--DDTSSLQALSE 59
              L+L+ +GP+Q+WG  +   TR T  +P++S ++G++ A  G +R  D   ++  L++
Sbjct: 1   MKSLLLKFSGPLQSWGTDSHFETRHTDYYPSKSAVIGMIAAAFGYRRSTDCDENIAKLND 60

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
            + FAVR D+            LRDYH               +   T R YL DA F VA
Sbjct: 61  -LDFAVRIDQ--------QGNLLRDYHIAAKY---KANGDFEKNYVTNRYYLEDAIFLVA 108

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGG 179
           +    +   +I ++  A+  P +   LGRRS P T    LG  +     +ALL +E +  
Sbjct: 109 I--GSNNEQLIYDISNALRSPYFQSSLGRRSLPPTADFILGV-EDCGVIQALLTHEWLAN 165

Query: 180 DIYSEES 186
               +  
Sbjct: 166 KWSKKRF 172


>UniRef50_A8SDR7 Putative uncharacterized protein n=1 Tax=Faecalibacterium
           prausnitzii M21/2 RepID=A8SDR7_9FIRM
          Length = 220

 Score =  173 bits (439), Expect = 4e-42,   Method: Composition-based stats.
 Identities = 75/221 (33%), Positives = 107/221 (48%), Gaps = 24/221 (10%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+LRLA P+QAWG  +   TR TGR PT+SG++GLL A LG++RD++ +L  L+  +
Sbjct: 1   MATLLLRLAAPLQAWGADSKFETRKTGREPTKSGVIGLLAAALGLRRDESEALTRLT-GL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +F VR +             L DYHT     E         +  T+R YL DA F   + 
Sbjct: 60  RFGVRVER--------EGQLLVDYHTAKTQDE-------KTSYVTYRHYLQDAVFLAGIE 104

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
            T   T ++ +L++A+L P +  YLGRR CP T PL LG C     Q+ L    P+    
Sbjct: 105 ST--DTALLQQLQQALLHPAFPLYLGRRCCPPTLPLCLGVCPG-SLQEVLQAEPPLCPGR 161

Query: 182 YSEESVTG---HHLKFTARDEPMITLP--RQFASREWYVIK 217
            S   +            RD P+   P  RQ+  R    + 
Sbjct: 162 QSRILLDADPLEPGTAPQRDVPVSFDPHHRQYGYRSVRELW 202


>UniRef50_B1VIY0 CRISPR-associated protein n=9 Tax=Actinomycetales
           RepID=B1VIY0_CORU7
          Length = 240

 Score =  173 bits (438), Expect = 4e-42,   Method: Composition-based stats.
 Identities = 60/234 (25%), Positives = 98/234 (41%), Gaps = 33/234 (14%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M   L+L L GPMQ+WG  +    R T   PT+SG++GL+ A  G +R D   ++ L+  
Sbjct: 1   MAHSLLLLLKGPMQSWGDESRFSVRATATTPTKSGIVGLIAAAQGRRRTD--GVEDLA-K 57

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           ++ AVR D+          + LRDY T       +            R +L DA+F  A+
Sbjct: 58  LRMAVRVDQS--------GSLLRDYQTAQ----PWLKNPGANASLVTRYFLSDAAFVAAV 105

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180
                   ++ ++ +A+ +P Y  Y+GRRSCP+   L +G     D + AL  ++     
Sbjct: 106 E--SEDRELLDQMAEALRRPAYPLYMGRRSCPVHPGLVIGVVDG-DAESALRAHDTWHAT 162

Query: 181 IYSEESV-------------TGHHLKFTARDEPMITLP--RQFASREWYVIKGG 219
               +                G       +D P+   P  R++  RE    +  
Sbjct: 163 AVHRKESPKKVSLAIYRDANPGEGGSVPRQDVPVSFSPEHRKYGWREVIRAEDV 216


>UniRef50_B0S4B6 Putative uncharacterized protein n=1 Tax=Finegoldia magna ATCC
           29328 RepID=B0S4B6_FINM2
          Length = 228

 Score =  172 bits (437), Expect = 5e-42,   Method: Composition-based stats.
 Identities = 54/234 (23%), Positives = 99/234 (42%), Gaps = 31/234 (13%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            S ++L+ A P+Q+WG       R T  +PT+S ++GL+ A  G ++ DT S++ L+ S+
Sbjct: 1   MSVILLKFASPLQSWGGLANYEIRNTEYYPTKSAVIGLVAAAFGYKKTDTESIKRLN-SL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETI---QTWREYLCDASFTV 118
            F+VR D+          + +RD+   +     Y     +  +      + Y+ DA F +
Sbjct: 60  NFSVRIDQ--------KGSLIRDFQIAMEYNPKYMPNDPNYFVKSNLIQKYYIQDAKFLI 111

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVG 178
           AL  +     ++ ++  A+  P Y  +LGR+S P+     +G    ++  + + +YE + 
Sbjct: 112 AL--SSDDETLMEDVYNALESPAYQLFLGRKSNPINADYLIGKFDGNEL-EIIKDYEWLA 168

Query: 179 GDIYSEESVTG--------------HHLKFTARDEPMIT--LPRQFASREWYVI 216
              Y +                      K   RD         R F+SR  Y  
Sbjct: 169 SKWYKKSIKKDSVELSIFSDYIDTGSKEKLIRRDLTESFENTKRDFSSRFEYRY 222


>UniRef50_UPI0001AF1D4C CRISPR-associated protein, CT1976 n=1 Tax=Streptomyces ghanaensis
           ATCC 14672 RepID=UPI0001AF1D4C
          Length = 244

 Score =  172 bits (437), Expect = 6e-42,   Method: Composition-based stats.
 Identities = 59/240 (24%), Positives = 89/240 (37%), Gaps = 41/240 (17%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L++    PMQ+WG  +   +R T   PT+SG++GLL A LGI RD    +Q L+E +
Sbjct: 1   MATLLMCFDAPMQSWGTRSQFASRDTATEPTKSGVVGLLAAALGIPRDADEEIQNLAE-L 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +  VR D   + +         D+HTV          K+H T  T R YL DA F V + 
Sbjct: 60  RMGVRVDREGVVEA--------DFHTVQNVPNTE--GKNHRTAVTKRFYLADALFLVGVE 109

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPL-FLGT------CQASDPQKALLNY 174
                T ++ +L  A+  PR+  Y GR++     P+   G               AL  +
Sbjct: 110 --SDDTQLLHQLHTALTAPRWPLYFGRKAFVPARPIPSPGLAGEHHPVTGQSLDDALRTH 167

Query: 175 EPVGGD-----------------IYSEESVTGH--HLKFTARDEPMITLP--RQFASREW 213
             +                                       D P+      R +A R  
Sbjct: 168 PWLENQLRIHANRRTTAYAPSPAWLRTIVDADPLALDVELRHDHPLSFTQQDRSYAPRAV 227


>UniRef50_Q1R114 CRISPR-associated protein, CT1976 n=1 Tax=Chromohalobacter
           salexigens DSM 3043 RepID=Q1R114_CHRSD
          Length = 260

 Score =  172 bits (436), Expect = 7e-42,   Method: Composition-based stats.
 Identities = 73/260 (28%), Positives = 106/260 (40%), Gaps = 52/260 (20%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M  +L+ RL  PM +WG+      RPT  +P R  +LGL+GA LGI+RDD      L +S
Sbjct: 1   MTGHLVFRLYAPMASWGEAAVGEARPTATYPGRGAILGLIGAALGIRRDDDEGQLRLRQS 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYR------------GLKSHETIQTWR 108
           +  AV+        +R     LRDYHTV       +               +  TI + R
Sbjct: 61  LGIAVK--------QRSPGWLLRDYHTVQVPPSQSKVNYRSRREELSVPKDALNTILSSR 112

Query: 109 EYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQ 168
           +Y CD  + VAL L P A   + EL+ A+ +PR+T YLGR++CPL  PL     +A   +
Sbjct: 113 DYRCDGLWVVALRLMPDAVWTLDELKSALERPRFTLYLGRKACPLAAPLTPAIVEADHWR 172

Query: 169 KAL---------LNYEPVG-----------------------GDIYSEESVTGHHLKFTA 196
            AL              +                        G+  + +           
Sbjct: 173 GALDHGFDSATDPERTWLPLIGNEAQDLRLLRLPGQVLYAWEGEADALDGNADMAESSET 232

Query: 197 RDEPMITLPRQFASREWYVI 216
            DEP+     QF +R  +  
Sbjct: 233 WDEPLHRRRWQFGARLEHRR 252


>UniRef50_Q47PI7 CRISPR-associated protein, Cas5e family n=12 Tax=Actinomycetales
           RepID=Q47PI7_THEFY
          Length = 245

 Score =  172 bits (436), Expect = 7e-42,   Method: Composition-based stats.
 Identities = 70/239 (29%), Positives = 101/239 (42%), Gaps = 36/239 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L L LAGP+QAWG  +    R T   PT+SG+LGLL A  G +R D   L  L+ ++
Sbjct: 1   MKVLTLLLAGPLQAWGAASRFTRRTTEHAPTKSGVLGLLAAAQGRERTDD--LSDLA-AL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +F VR D+          T +RD+ T +                + R YL DA F  A+ 
Sbjct: 58  RFGVRVDQ--------RGTRIRDFQTAIHLD------TGKSMPVSERFYLADAVFVAAVE 103

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                  +I  L +AV  P Y PYLGRRSCP + P+ LG       ++ L   +    + 
Sbjct: 104 ---GEDTLIDTLHQAVQHPVYLPYLGRRSCPPSRPINLGVHSGKPLEQVLAEEKWHAANW 160

Query: 182 YSE--------------ESVTGHHLKFTARDEPMITLP--RQFASREWYVIKGGMDVSQ 224
           Y                ++  G     + RD P+   P  R++A R    +   +   Q
Sbjct: 161 YQRQLRDLPEVPLDLLVDAPPGDPGADSLRDLPISFDPVHRRYALRGVRTLTVTVPNPQ 219


>UniRef50_Q1EQS9 CRISPR-associated protein n=3 Tax=Streptomyces RepID=Q1EQS9_STRKN
          Length = 280

 Score =  172 bits (436), Expect = 8e-42,   Method: Composition-based stats.
 Identities = 70/241 (29%), Positives = 107/241 (44%), Gaps = 39/241 (16%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           L+LRL+GP+Q+WG+ +    R T RFPTRSG++G+L A LG +R     +  L+  +   
Sbjct: 14  LLLRLSGPLQSWGERSHFNERDTARFPTRSGIIGMLAAALGRRRG--EPVDDLA-RLSLT 70

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKS---------HETIQTWREYLCDAS 115
           VR D             LRD HTV G       + +           T+ T R YL DA+
Sbjct: 71  VRTDR--------PGILLRDLHTVGGGLPAKATVTTAEGKKRPGTTGTLLTHRTYLADAA 122

Query: 116 FTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQAS------DPQK 169
           FT+AL  TP    ++ +  +A+  P +  +LGRRSCP   PL LG  + +       P  
Sbjct: 123 FTIALTSTPDDRPLLDQAAQALNTPCWPLFLGRRSCPPEGPLLLGASEDALHHLVHLPLA 182

Query: 170 ALLNYEPVGGDIYSEESV-------------TGHHLKFTARDEPMITLPRQFASREWYVI 216
           A         +  ++  +              G H      D+P+   PR+ + R   + 
Sbjct: 183 AHPGRGQQDTEFLADRPLNRLPYGTATPVGADGTHPSGEVNDQPLSFDPRRRSYRARPLY 242

Query: 217 K 217
           +
Sbjct: 243 R 243


>UniRef50_A8M404 CRISPR-associated protein Cas5 family n=1 Tax=Salinispora arenicola
           CNS-205 RepID=A8M404_SALAI
          Length = 238

 Score =  172 bits (435), Expect = 9e-42,   Method: Composition-based stats.
 Identities = 65/234 (27%), Positives = 97/234 (41%), Gaps = 35/234 (14%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
            L+LRLAGP+Q+WG  +    R T   PT+SG++G+L A  G++R D   L  L  S+ F
Sbjct: 1   MLLLRLAGPLQSWGATSRFTHRHTQVTPTKSGVIGMLAAASGLRRTD--PLTELL-SLDF 57

Query: 64  AVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLT 123
            VR D+            LRD+                    T R YL DA F VA+   
Sbjct: 58  GVRIDQ--------PGQLLRDFQVARTLDG------RDSMPLTNRYYLSDAVFLVAI--- 100

Query: 124 PHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDIYS 183
                ++  L ++V +P +  YLGRR+CP   P+ LG        +AL ++         
Sbjct: 101 GGDQALLEGLHESVRRPHFPLYLGRRACPPVAPISLGVHPG-TVDEALRDWPWQAAKRLR 159

Query: 184 EE------------SVTGHHLKFTARDEPMITLP--RQFASREWYVIKGGMDVS 223
           E             +  G  +  T  D+P+   P  RQ+  R     +  +   
Sbjct: 160 ERGELTVPLEVVSDAPPGADVTETLPDQPISFDPAHRQYGWRAVVRTRIVVPNP 213


>UniRef50_Q2JWC5 CRISPR-associated protein Cas5, Ecoli subtype n=1 Tax=Synechococcus
           sp. JA-3-3Ab RepID=Q2JWC5_SYNJA
          Length = 207

 Score =  172 bits (435), Expect = 1e-41,   Method: Composition-based stats.
 Identities = 49/217 (22%), Positives = 88/217 (40%), Gaps = 31/217 (14%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L++RL  PM +WG  +    R + R PT+S ++G+L A LG  R     +  L+ ++
Sbjct: 1   MTTLLMRLRAPMMSWGDHSQFDYRDSRREPTKSAVIGILCAALGRPR--WEPVDDLA-AL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +  VR ++             +D+HTV                 + R Y+ D  + V L 
Sbjct: 58  KMGVRVNK--------EGILCKDFHTVQIKE-----------TISNRYYVADGDYLVGLE 98

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                  ++  L++A+ KP +  +LGR+S   + PL +G  +     +AL  +       
Sbjct: 99  ---GDPNLLRTLDQALQKPYWQVFLGRKSFIPSRPLRVGLVEQP-LLEALRQHPYECSRR 154

Query: 182 YSEE-----SVTGHHLKFTARDEPMITLPRQFASREW 213
                     +         +D P+   PR+F  R  
Sbjct: 155 GKRPSQLRFVLEVSESLDVRQDVPLSWQPRRFGCRAV 191


>UniRef50_A1SV73 CRISPR-associated protein, Cas5e family n=2 Tax=Gammaproteobacteria
           RepID=A1SV73_PSYIN
          Length = 217

 Score =  171 bits (434), Expect = 1e-41,   Method: Composition-based stats.
 Identities = 78/214 (36%), Positives = 109/214 (50%), Gaps = 15/214 (7%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              LIL+  G M A+G  TF+  R    FPTRS ++G+LGA +GI R++ + L ALSE +
Sbjct: 1   MKTLILKTEG-MSAYGLQTFDVHRRANHFPTRSAIMGILGAAMGITRENFNELYALSEQL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           + AV+          +S   + DYHTV   R    G        T+REY CD+  T A+ 
Sbjct: 60  KIAVQV--------NLSGEKMVDYHTVQHFRSPQ-GKIQKGVKPTYREYWCDSEHTFAIS 110

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
               A  VI +L  +V  P +T + GR+SCPLT PLF       +P  AL N+    G I
Sbjct: 111 A---AEHVIEKLVNSVKFPEFTLFQGRKSCPLTRPLFEAVTDDDNPANALKNHGEQ-GQI 166

Query: 182 YSEESVTGHHLKFTARDEPMITLPRQFASREWYV 215
           +S+ S          RD  +  +PR++A R  YV
Sbjct: 167 FSDISGDNQLAIVQVRDL-ITAIPRKYAMRTVYV 199


>UniRef50_A5UR14 CRISPR-associated protein, Cas5e family n=1 Tax=Roseiflexus sp.
           RS-1 RepID=A5UR14_ROSS1
          Length = 262

 Score =  171 bits (433), Expect = 2e-41,   Method: Composition-based stats.
 Identities = 74/259 (28%), Positives = 101/259 (38%), Gaps = 55/259 (21%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L LRL GP+Q+WG     G R T   PT+SG++GLLG  LG++RDD + L+ LS+++
Sbjct: 1   MNTLFLRLEGPLQSWGLRARWGERDTTDAPTKSGVIGLLGCALGLRRDD-ARLRDLSDNL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSH-------------------- 101
           +  VR D        +    +RDYHT  G R                             
Sbjct: 60  RMGVRVD--------LPGILMRDYHTTGGGRYSTIASTGGPRYHDEPYIGGVLSAEVTKG 111

Query: 102 -------------ETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGR 148
                        ET  + R YL DASF VAL  +P     I EL  A+  P +  +LGR
Sbjct: 112 RIKVKINQKTGEPETDVSERYYLADASFLVALQGSPD---YIGELATAIQSPVWPLFLGR 168

Query: 149 RSCPLTHPLFLGTCQASDPQKALLN---YEPVGGDIYSEESVT-------GHHLKFTARD 198
           ++C  + P+F GT Q    + AL N      V                  G        D
Sbjct: 169 KACVPSTPIFAGTGQFDILEDALKNLLLSPRVETAWQRSRPTQLRLLIETGPGAGNRQYD 228

Query: 199 EPMITLPRQFASREWYVIK 217
                  R F +R      
Sbjct: 229 NIGTPSRRVFRARYVRETW 247


>UniRef50_B2GBJ9 Putative uncharacterized protein n=1 Tax=Lactobacillus fermentum
           IFO 3956 RepID=B2GBJ9_LACF3
          Length = 235

 Score =  171 bits (433), Expect = 2e-41,   Method: Composition-based stats.
 Identities = 54/206 (26%), Positives = 81/206 (39%), Gaps = 23/206 (11%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQR--DDTSSLQALSE 59
              L++R+A P+Q++G P     R T R P++S ++G++GA LG +R  DD  SL  L  
Sbjct: 1   MKTLVIRIAAPLQSYGDPASFEKRTTFRAPSKSAVIGMIGAALGFRRESDDYKSLNDLD- 59

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
              FAVR D+            L D+                    + R YL DA F VA
Sbjct: 60  ---FAVRVDQ--------PGEVLSDFQITH-------YSLKKPGKLSHRIYLQDAVFMVA 101

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGG 179
           L     A  ++ E+E A+  P++  Y GRRS P    L +  C        L        
Sbjct: 102 LSSKQDA--LMEEIEYALRHPKFQLYFGRRSNPPAGILKMKMCPDKTAINVLKELPWQAS 159

Query: 180 DIYSEESVTGHHLKFTARDEPMITLP 205
             +  +            D  ++   
Sbjct: 160 VWFQRKYKKDVFNARIYADAKLVPDR 185


>UniRef50_C7MQD6 CRISPR-associated protein Cas5 n=1 Tax=Saccharomonospora viridis
           DSM 43017 RepID=C7MQD6_SACVD
          Length = 236

 Score =  170 bits (431), Expect = 3e-41,   Method: Composition-based stats.
 Identities = 71/219 (32%), Positives = 104/219 (47%), Gaps = 20/219 (9%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+L L GPMQAWG  +    R T  +PTRSG++G++ A LG Q  D  SL  LS  +
Sbjct: 1   MTTLVLHLDGPMQAWGHASQWDHRDTLDYPTRSGVIGMIAAALGKQWGD--SLDDLSP-L 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGARE----DYRGLKSHETIQTWREYLCDASFT 117
           +F +R D             + DYHT  G  E      +G      + + R Y+ DA++T
Sbjct: 58  RFTIRIDR--------PGRRIVDYHTAGGGYEVGIARVKGGNRAHAVLSDRFYMSDAAYT 109

Query: 118 VALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQK-ALLNYEP 176
           VA+        ++  ++ A+  P + P+LGRRSCP   P  LG       +   L   +P
Sbjct: 110 VAIT---GPDTLLYRVDDALRAPVFGPFLGRRSCPPAGPWHLGLHDGDPLRTLPLHRDKP 166

Query: 177 VGGDIYSEESVTGHHL-KFTARDEPMITLPRQFASREWY 214
             GD  + E V+ H     T R +  +T P +F  R  Y
Sbjct: 167 RDGDTVAVEFVSDHETHGPTDRVDTTLTDPHEFGPRRSY 205


>UniRef50_C7LYW6 CRISPR-associated protein Cas5 family n=1 Tax=Acidimicrobium
           ferrooxidans DSM 10331 RepID=C7LYW6_ACIFD
          Length = 253

 Score =  169 bits (429), Expect = 5e-41,   Method: Composition-based stats.
 Identities = 73/238 (30%), Positives = 94/238 (39%), Gaps = 41/238 (17%)

Query: 2   RSYLILRLAGPMQAWGQPTF-EGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
            S L LRL GP+QAWG     +  R T RFPT+SG++GLL A LG  R   ++L  L  +
Sbjct: 1   MSVLALRLGGPLQAWGSSQRLDHYRRTERFPTKSGVIGLLAAALGRPRS--AALDDLG-A 57

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHE----------------TI 104
           ++FAVR D             LRD+HT+    +D +     E                T 
Sbjct: 58  LRFAVRIDR--------PGEVLRDFHTLSSLFDDKKRFAPGEGRLPTASGGYRSAATSTQ 109

Query: 105 QTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQA 164
            T R YL DA F   L         + EL+ A+  P +  YLGRRSCP   PL LG    
Sbjct: 110 VTERFYLADACFVAGLE---GDAAQLQELDDALRTPVFPLYLGRRSCPPDKPLRLGVYDG 166

Query: 165 SDPQKALLNYEPVGGDIYS-------EESVTGHHLKFTARDEPMITLP--RQFASREW 213
                 L +      D          E  V          D+     P  R +  R  
Sbjct: 167 -GLIDVLASIPWQANDPAQSATSIRCELVVENPAGDVELADQARSFDPLTRSYTRRRV 223


>UniRef50_Q03C60 CRISPR-associated protein n=4 Tax=Lactobacillus RepID=Q03C60_LACC3
          Length = 236

 Score =  168 bits (425), Expect = 2e-40,   Method: Composition-based stats.
 Identities = 57/240 (23%), Positives = 91/240 (37%), Gaps = 37/240 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              + +RL  P+Q++G       R TG +P++S ++G+L A LG QRDD  ++ AL++ +
Sbjct: 1   MKTISIRLTSPLQSYGNEAQFARRTTGDYPSKSAIIGMLAAALGYQRDD-PAINALNDLL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
            FAVR D+            + ++ T           K      T+R+ L DA F VA+ 
Sbjct: 60  -FAVRVDQ--------PGQVMTEFQTAE--------WKPGTRKLTYRDLLQDAVFVVAI- 101

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                   +  L +A+  PR+  YLGRR+      L + T    DP   L          
Sbjct: 102 -GSEDEAWLDRLAEALRHPRFQLYLGRRANVPAGVLKIQTFAGQDPVGVLAQLPWQASRW 160

Query: 182 YSEES----------------VTGHHLKFTARDE-PMITLPRQFASREWYVIKGGMDVSQ 224
           Y   S                +                   RQ++ R   V K  +   +
Sbjct: 161 YQRRSRRQASMSVQLIADAVLLPERRADLVRDAVHSFDQKHRQYSFRPIAVTKVQLANPE 220


>UniRef50_A8ZZ17 CRISPR-associated protein Cas5 family n=1 Tax=Desulfococcus
           oleovorans Hxd3 RepID=A8ZZ17_DESOH
          Length = 259

 Score =  167 bits (423), Expect = 2e-40,   Method: Composition-based stats.
 Identities = 66/260 (25%), Positives = 98/260 (37%), Gaps = 54/260 (20%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             YL+ RL GPM +WG+     TR T  +P RS ++GL+ A LGI+R +T + QAL +  
Sbjct: 1   MGYLLFRLYGPMASWGEIAVGETRHTANYPGRSAIIGLMAAALGIKRSETENQQALDQGC 60

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGA------------REDYRGLKSHETIQTWRE 109
             AV        + R   + LRDYHT                 E   G     TI + RE
Sbjct: 61  LIAV--------EARSHGSLLRDYHTTQVPDSVGGFVYRTRRDELIIGKPRLGTILSSRE 112

Query: 110 YLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGT-CQASDPQ 168
           Y  DA    A+ + P A   +  ++  + +PR   YLGR+SCPL+ P+       + +  
Sbjct: 113 YRQDALAVSAVRVLPGARYELQTIKTHLEQPRLHVYLGRKSCPLSAPMNPQIDKTSRNFH 172

Query: 169 KALLNYEPVGGDIYSEESVTG---------------------------------HHLKFT 195
           +A   Y              G                                       
Sbjct: 173 EAFQAYAHQPLLPVHHSGKEGLSKRDAYWLGLANDRHYYWEGEPSEFSDTIDLSRVQTRI 232

Query: 196 ARDEPMITLPRQFASREWYV 215
             D+P+     QF+ R+ + 
Sbjct: 233 RHDQPLSRTRWQFSPRQEHY 252


>UniRef50_D2L2X8 CRISPR-associated protein Cas5 family n=1 Tax=Desulfovibrio sp.
           FW1012B RepID=D2L2X8_9DELT
          Length = 266

 Score =  164 bits (416), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 70/249 (28%), Positives = 97/249 (38%), Gaps = 45/249 (18%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M  YLI +L G + A+G       R +   PTRS + GLL ACLGI+R + + L ALS  
Sbjct: 1   MARYLIFQLYGMLAAYGLVAVGEVRLSAGHPTRSAVFGLLAACLGIRRHEEARLAALSGG 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRG---------------LKSHETIQ 105
              AVR D           T L DYHT+    E  +                 +   T+ 
Sbjct: 61  YALAVRVD--------APGTSLLDYHTIQTPPEKSKRIYRTRADELGGLLGIDEPPYTVL 112

Query: 106 TWREYLCDASFTVALW------LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFL 159
           + R YLCDA FT  L               +  L +A+ +P  TPYLGR+SCP + P   
Sbjct: 113 SRRGYLCDAHFTACLTPAAAPPTDATPPHTLEALAEALRRPVLTPYLGRKSCPPSLPFHP 172

Query: 160 GTCQASDPQKALLNY------------EPVGGDIYSEESVTGHHLKFT----ARDEPMIT 203
              +    + AL +Y                  ++++E         T     RD  +  
Sbjct: 173 RLGEYDSLEAALADYPLEKLAFPAGLKPHDPAVVFADEDEAITPATVTSRPLVRDRTVQH 232

Query: 204 LPRQFASRE 212
             R F  R 
Sbjct: 233 GRRLFEERR 241


>UniRef50_B8IZA7 CRISPR-associated protein Cas5 family n=1 Tax=Desulfovibrio
           desulfuricans subsp. desulfuricans str. ATCC 27774
           RepID=B8IZA7_DESDA
          Length = 249

 Score =  163 bits (413), Expect = 3e-39,   Method: Composition-based stats.
 Identities = 53/214 (24%), Positives = 86/214 (40%), Gaps = 13/214 (6%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE----- 59
           L LRL  PM ++G  +    R T   P++S + G+L A  G+ R        L +     
Sbjct: 8   LALRLQAPMLSFGNESRFNRRCTASLPSKSVVAGMLCAAKGLHRGSVEEQAFLQQVAAIP 67

Query: 60  SVQFAV-RCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV 118
            +  A+ RC      D  ++     D+HTV G R+   G    +   T R YL D+SF V
Sbjct: 68  MLSVAIPRCLSANGKDWLLAAGRTVDFHTVQGTRKAAGG--IKDCHITTRHYLHDSSFAV 125

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTC--QASDPQKALLNYEP 176
            L        V+ +  +A+  P +  ++GR+ C  + P+F G    +A      L     
Sbjct: 126 FL---NGPYRVLEDAARALQNPVWGLWIGRKCCIPSAPVFGGLFSSEAVALNHMLDAPLE 182

Query: 177 VGGDIYSEESVTGHHLKFTARDEPMITLPRQFAS 210
                    S    +     + E  ++  R+FA 
Sbjct: 183 FFTHEREVHSFEDGNDTVPDQAESFLSAARRFAP 216


>UniRef50_Q2RY19 CRISPR-associated protein, Cas5e family n=1 Tax=Rhodospirillum
           rubrum ATCC 11170 RepID=Q2RY19_RHORT
          Length = 261

 Score =  163 bits (412), Expect = 5e-39,   Method: Composition-based stats.
 Identities = 69/214 (32%), Positives = 94/214 (43%), Gaps = 21/214 (9%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
            +L+ RL GPM AWG       R T   P +S +LGLL A LGI R D ++ +AL   + 
Sbjct: 5   DFLVFRLVGPMAAWGDIAVGERRGTWDVPAKSAILGLLAAGLGIDRADRTAHEALDRGLG 64

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGA----------REDYRGLKSHETIQTWREYLC 112
           FAVR D             LRDYHT              R D        T+ + R Y  
Sbjct: 65  FAVRQDR--------PGRLLRDYHTAQAPKARKNARWSTRRDELNDDDLNTVLSDRLYRT 116

Query: 113 DASFTVALWLTPH-ATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKAL 171
           +A  T A+W         + +L +A+L+PR+TPYLGR++CPL  P      QA     A 
Sbjct: 117 NAIATPAIWRRQGTEGPTLDQLTQALLRPRFTPYLGRKACPLGWPPRPRLLQADGLLAAF 176

Query: 172 LNYEPVGGDIYSE--ESVTGHHLKFTARDEPMIT 203
             Y+    D   +  ++  G     T R  P+  
Sbjct: 177 DAYDSAEWDAARQFHKAYPGGWPGDTDRPTPVWF 210


>UniRef50_C8XAY4 CRISPR-associated protein Cas5 family n=2 Tax=Actinomycetales
           RepID=C8XAY4_NAKMY
          Length = 252

 Score =  162 bits (409), Expect = 1e-38,   Method: Composition-based stats.
 Identities = 63/249 (25%), Positives = 94/249 (37%), Gaps = 47/249 (18%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            S L+LRL GPMQ+WG+ +    R T   P++S ++GLL A LG +R D  +++ L+  +
Sbjct: 1   MSVLVLRLTGPMQSWGERSRYARRETAAEPSKSAIVGLLAAALGRRRTD--AIEDLA-GL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
            F VR D+          T LRD+ T                  + R YL DA F  A+ 
Sbjct: 58  IFGVRVDQ--------PGTLLRDFQTARSLDGAR------TMPLSERYYLSDARFLAAVE 103

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLG-TCQASDPQKALLNYEPVGGD 180
                  +I+ L  A+  P +  YLGRRSCP + P+      ++     AL +       
Sbjct: 104 ---GPESLIAGLAGALRDPTFPLYLGRRSCPPSEPIAQQDCIRSGPLLAALFDEPWHATK 160

Query: 181 IYSEESVT------------------------GHHLKFTARDEPMITLP--RQFASREWY 214
            Y                                 +    RD P+   P  R +  R   
Sbjct: 161 SYRRRVADPARLSIAVDAAATEVPAQLAERLTDPEVPQLVRDHPVSFDPRARTYGLRSVI 220

Query: 215 VIKGGMDVS 223
                +D  
Sbjct: 221 RGAVVVDNP 229


>UniRef50_A8LYZ7 CRISPR-associated protein Cas5 family n=2 Tax=Actinomycetales
           RepID=A8LYZ7_SALAI
          Length = 257

 Score =  161 bits (407), Expect = 2e-38,   Method: Composition-based stats.
 Identities = 75/244 (30%), Positives = 104/244 (42%), Gaps = 43/244 (17%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+LRLAGPMQ+WG  +    R TG  PTRS ++G++ A  G  R     L  L+  V
Sbjct: 1   MTGLLLRLAGPMQSWGDHSTFSVRDTGTVPTRSAMIGIIAAAQGRHRG--EPLGDLAP-V 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLK---------SHETIQTWREYLC 112
           QF VR D           T + D+HTV G     R +             TI + R YL 
Sbjct: 58  QFTVRVDR--------PGTVMSDFHTVGGGAPPERTVPTAEGKRRTAGAGTIVSRRFYLA 109

Query: 113 DASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKAL- 171
           DA FTVA+        ++ ++  A+  P + PYLGRRSCP+ HP  +      DP   L 
Sbjct: 110 DAVFTVAVTGPDD---LVGQIHTALNNPVWGPYLGRRSCPVAHPFLMS-GPIPDPVGRLE 165

Query: 172 -----LNYEPVGGDIYSEESV------TGHHLKFTARDEPM-------ITLPRQFASREW 213
                    P   +    + V       G   + T  D PM           R++ +R+ 
Sbjct: 166 HLPLNRRRPPGDEETVRVDFVTGAPHGDGSISRMTLNDVPMEPVPGSPDPRRRRYLTRQV 225

Query: 214 YVIK 217
           YV  
Sbjct: 226 YVTT 229


>UniRef50_D1A6Q5 CRISPR-associated protein Cas5 family n=2 Tax=Actinomycetales
           RepID=D1A6Q5_THECD
          Length = 273

 Score =  160 bits (406), Expect = 2e-38,   Method: Composition-based stats.
 Identities = 72/244 (29%), Positives = 107/244 (43%), Gaps = 44/244 (18%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
           + L+L L+GP+Q+WG+ +    R T   PTRSGL+G++ A  G +R     +  L  +++
Sbjct: 7   TGLLLHLSGPLQSWGERSRFNQRDTATAPTRSGLIGMIAAAFGRRRT--EPVTDL-RALR 63

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGA---------REDYRGLKSHETIQTWREYLCD 113
           F VR D           T LRD+HTV G           E  R      T+ + R YL D
Sbjct: 64  FTVRIDR--------PGTLLRDFHTVGGGMPRDLTVITAEGKRRAADTATVTSDRYYLQD 115

Query: 114 ASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLN 173
           A+FTVA+        ++    +A+  PR+  YLGRRSCP   PL L   + +DP  AL++
Sbjct: 116 AAFTVAVTA--DDPALLDRCAQALRAPRWPLYLGRRSCPPNAPLLLTVLR-TDPVTALID 172

Query: 174 YE-------------------PVGGDIYSEESVTGHHLKFTARDEPMITLP--RQFASRE 212
                                          +     +   A+DEP+   P  R+F +R 
Sbjct: 173 LPLARTAPRDRGDVLVEFRSDTPFESRAWPSAPEDEQVYTEAQDEPVSFQPHHRRFQTRP 232

Query: 213 WYVI 216
            Y  
Sbjct: 233 IYRR 236


>UniRef50_Q2JH27 CRISPR-associated protein, CT1976 n=6 Tax=Actinomycetales
           RepID=Q2JH27_FRASC
          Length = 276

 Score =  160 bits (406), Expect = 3e-38,   Method: Composition-based stats.
 Identities = 71/252 (28%), Positives = 94/252 (37%), Gaps = 52/252 (20%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           L+LRLAGP+Q+WG  +    R T   PT+SG++GLL A  G +R D   ++ L  S+   
Sbjct: 10  LVLRLAGPLQSWGSRSMFNRRDTLTEPTKSGIIGLLAAAQGRRRTD--PIEDLL-SLTLG 66

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGARED-------------YRGLKSHETIQTWREYL 111
           +R D+          T LRDYHTV   R                    +  T  T R YL
Sbjct: 67  IRTDQ--------PGTLLRDYHTVSDYRGRPLPSAAVSAKGLQKPTSPAKHTHVTERFYL 118

Query: 112 CDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDP---- 167
            DA F  AL        V++ L  A+  P +   LGRR+CP THPL L      D     
Sbjct: 119 QDAVFVAALAAP---EPVLTTLADALRTPAFPLALGRRACPPTHPLLLVPDSEPDAALWS 175

Query: 168 ---QKALLNYEPVGGDIYSEES----------------VTGHHLKFTARDEPMITLP--R 206
               + L          + +                  V          D P    P  R
Sbjct: 176 GSALEVLRQVPWQARPDHRDALARRRPPRLRRIDLPVTVDDPDGDDVRIDLPTTFDPHQR 235

Query: 207 QFASREWYVIKG 218
            F SR  +    
Sbjct: 236 GFTSRRVHQSWV 247


>UniRef50_D1CAJ0 CRISPR-associated protein Cas5 family n=1 Tax=Sphaerobacter
           thermophilus DSM 20745 RepID=D1CAJ0_SPHTD
          Length = 245

 Score =  160 bits (405), Expect = 3e-38,   Method: Composition-based stats.
 Identities = 62/246 (25%), Positives = 93/246 (37%), Gaps = 42/246 (17%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            S L+LRL GPMQAWG  +    R TG  P++SG++GLL A LG  R   + +  L+  +
Sbjct: 1   MSTLLLRLTGPMQAWGTQSRFSWRDTGLEPSKSGVIGLLCAALGRPRS--APVDDLA-RL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRG--------LKSHETIQTWREYLCD 113
           +  VR D           T   D+HT  G                 +     + R YL D
Sbjct: 58  RMGVRVDR--------EGTMHVDFHTAGGWHRRAEAGYGVPDPSGTARRPQISRRFYLAD 109

Query: 114 ASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTH--------PLFLGTCQAS 165
           A F V L        ++  L++A+  PR+  +LGR+S             P   G     
Sbjct: 110 ADFLVGLE---GDEELLVLLDRALAAPRWQLFLGRKSFVPAAPVRLPDTPPWGPGLRPEP 166

Query: 166 DPQKALLNYEPVGGDIYSEESV-----------TGHHLKFTARDEPMITLPRQFASREWY 214
             + AL  Y  +G  +    +             G        D P+    R+F++R   
Sbjct: 167 -LETALRTYPWLGYQLPHPRADAPDRLRLVLDAEGDDAADIRMDVPISFAERRFSTRAVR 225

Query: 215 VIKGGM 220
            +    
Sbjct: 226 TVWIAT 231


>UniRef50_C5SD48 CRISPR-associated protein Cas5 family n=1 Tax=Allochromatium
           vinosum DSM 180 RepID=C5SD48_CHRVI
          Length = 227

 Score =  160 bits (404), Expect = 4e-38,   Method: Composition-based stats.
 Identities = 107/225 (47%), Positives = 133/225 (59%), Gaps = 9/225 (4%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M SYLILRL GPMQAWG  TFE  RP+  FPTRSGLLGLLGACLG+ R DT SL AL+ES
Sbjct: 1   MPSYLILRLDGPMQAWGTHTFEDYRPSNPFPTRSGLLGLLGACLGLDRSDTPSLDALAES 60

Query: 61  VQFAVRCDELILDD-----RRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDAS 115
           V F VR D                T L DYHTVL AR+   G  +   IQ+ REYL DA+
Sbjct: 61  VAFTVRLDTGAPRPGVDRLMPKRHTKLSDYHTVLDARKV-DGSTNKFPIQSHREYLFDAA 119

Query: 116 FTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPL--FLGTCQASDPQKALLN 173
           F VA+   P A+  ++ + +++ +PR+TP LGRRSCPL  PL       +A D + AL  
Sbjct: 120 FAVAIGSRPDASFSLARIAESLRQPRFTPVLGRRSCPLGRPLLERPDCIEADDAKAALAQ 179

Query: 174 YEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKG 218
           + P GG IYSE+ +      +   D P     RQFA+R  Y+ + 
Sbjct: 180 FPPHGGLIYSEDELVSDQPTWIR-DVPRYGRHRQFATRRLYLHRE 223


>UniRef50_C9M9R7 CRISPR-associated protein Cas5, Ecoli subtype n=1 Tax=Jonquetella
           anthropi E3_33 E1 RepID=C9M9R7_9BACT
          Length = 243

 Score =  159 bits (401), Expect = 1e-37,   Method: Composition-based stats.
 Identities = 58/222 (26%), Positives = 90/222 (40%), Gaps = 19/222 (8%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             +L+LR  GPM ++G    +  RP  RFP  S + GL+   LG    +T  LQAL + +
Sbjct: 1   MDFLVLRFRGPMMSFGDVAVDEQRPIDRFPGVSMVTGLVANALGWDWSETEKLQALQDRL 60

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHT----------VLGAREDYRGLKSHETIQTWREYL 111
             AVR D         +   LR+Y T          V  +    R L    T+Q +  Y 
Sbjct: 61  VLAVREDR--------AGERLREYQTVALPGKSGLFVTHSIPCSRNLDKPMTVQKYLSYW 112

Query: 112 CDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLG-TCQASDPQKA 170
            ++  T  + LT   T  + E+  A+ KP    +LGR++C  T P+F G    A  P++A
Sbjct: 113 ANSLITCFIALTGLGTPTLDEIACALKKPARPLFLGRKTCLPTEPVFRGEIFGAESPEEA 172

Query: 171 LLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASRE 212
           +L    +              +     D   +    +   R 
Sbjct: 173 VLRSCQLDKRPLKFVESPHSCVVEWPYDGRTVVSQSEIFERR 214


>UniRef50_C7MTB0 CRISPR-associated protein Cas5 n=1 Tax=Saccharomonospora viridis
           DSM 43017 RepID=C7MTB0_SACVD
          Length = 255

 Score =  158 bits (400), Expect = 1e-37,   Method: Composition-based stats.
 Identities = 75/237 (31%), Positives = 104/237 (43%), Gaps = 36/237 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            S L+LRLAGP+Q+WG+ +    R T  FPT SGLLGLL   +G +R    SL+ L+ ++
Sbjct: 1   MSGLLLRLAGPLQSWGERSTFDVRDTAGFPTHSGLLGLLACVMGRRRG--ESLEDLA-AL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLK---------SHETIQTWREYLC 112
            F +R D           T + DY T  GA      +             T+QTWREYL 
Sbjct: 58  TFTIRVDR--------PGTRIIDYQTAGGALPPSMKVPTADGKGRPAGKGTVQTWREYLA 109

Query: 113 DASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALL 172
           DA F VA+      + V+ ++  A+  P + PYLGRRSCP   PL L      DP   L 
Sbjct: 110 DAVFVVAV---QGPSEVLDQVRHALRYPHWQPYLGRRSCPPDQPLLLDV-PVEDPVAELC 165

Query: 173 NYEPVGGDIYSEESVTGHHLKFTA----------RDEPMITL--PRQFASREWYVIK 217
              P+   +  +E        F             D P+      R ++ R  +   
Sbjct: 166 TRVPLARRVGKDEETVPVDFIFPVERRDGVRSEIHDVPVAFTSVDRAYSPRPVWRST 222


>UniRef50_B3E5U9 CRISPR-associated protein Cas5 family n=2 Tax=Desulfuromonadales
           RepID=B3E5U9_GEOLS
          Length = 271

 Score =  156 bits (395), Expect = 4e-37,   Method: Composition-based stats.
 Identities = 74/272 (27%), Positives = 105/272 (38%), Gaps = 66/272 (24%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             YL+ RL GP+ +WG+     +R +  +P +S LLGL+ A LGI+RD+     AL+   
Sbjct: 1   MKYLLFRLYGPLASWGEIAVGESRHSAVYPGKSALLGLIAAALGIRRDEEQRQAALASGY 60

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGA------------REDYRGLKSHETIQTWRE 109
           +FAV+               LRDYHT                 E   G +   TI + RE
Sbjct: 61  RFAVKVIST--------GHPLRDYHTAQAPDSVGKFVYRTRRDELVLGKERLGTILSSRE 112

Query: 110 YLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQK 169
           Y CDA   VA+     A   + E+ +A++KPR+  YLGR+SCP+  PL      A     
Sbjct: 113 YRCDAFSLVAVVAEDDAPYSLDEIREALMKPRFHLYLGRKSCPVAAPLNPLVRDAVGFGD 172

Query: 170 ALLNYE-------PVGGDIYSEESVTGHHLKF---------------------------- 194
           AL +Y                +E V G  L                              
Sbjct: 173 ALDSYPYGALFVSSWLMKTAQKEIVEGGKLAEVPSLAKFSREDETVFAYNKQPVRYYWEG 232

Query: 195 -----------TARDEPMITLPRQFASREWYV 215
                      T  D+P+     QF+ R  Y+
Sbjct: 233 DAGDLVSQQSLTRHDQPLSRNRWQFSQRTEYL 264


>UniRef50_B8GIV3 CRISPR-associated protein Cas5 family n=1 Tax=Methanosphaerula
           palustris E1-9c RepID=B8GIV3_METPE
          Length = 257

 Score =  156 bits (394), Expect = 6e-37,   Method: Composition-based stats.
 Identities = 69/239 (28%), Positives = 94/239 (39%), Gaps = 37/239 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             YL   L G M +WG       RPT   PTRS +LGLL A LGI+RD+   L AL+ + 
Sbjct: 4   PEYLTFSLYGMMASWGDIAVGEYRPTADHPTRSAVLGLLAAALGIRRDEEERLAALTRAY 63

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRG-------------LKSHETIQTWR 108
           + A+R D             LRDYHT        +G              +   TI + R
Sbjct: 64  KVAIRVD--------APGMLLRDYHTTQVPSAAKKGRQYLTRKDELAAPREVLNTILSTR 115

Query: 109 EYLCDASFTVALWLTPHATMV-ISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDP 167
           +Y CDA + V +W    A    +  L + +  P +T YLGR+SCPL  P+      A D 
Sbjct: 116 DYRCDAVYRVYIWCRDTAPPYSLKTLAEHLQHPVFTLYLGRKSCPLALPVNPEVKTAPDL 175

Query: 168 QKALLNYEPVGGDIY------SEESVTGHH---------LKFTARDEPMITLPRQFASR 211
             AL     +            + +V  +                DE +     QF  R
Sbjct: 176 LTALSEEREIELRFLGRVPGNRDSNVRAYWDCTEGIQAEGTSVRNDESLNRRRWQFGRR 234


>UniRef50_Q0AA33 CRISPR-associated protein Cas5 family n=2 Tax=Gammaproteobacteria
           RepID=Q0AA33_ALHEH
          Length = 242

 Score =  156 bits (394), Expect = 6e-37,   Method: Composition-based stats.
 Identities = 53/232 (22%), Positives = 78/232 (33%), Gaps = 24/232 (10%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              LILRL  P+ ++G    +   PT RFP RS L G+L   LG    DT +L +L   +
Sbjct: 1   MPCLILRLDAPLMSFGGVLVDQHNPTDRFPGRSMLTGMLANALGWHHQDTEALNSLQARI 60

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTV---------------LGAREDYRGLKSHETIQT 106
            +A R D        V    LRDY TV                       G       Q 
Sbjct: 61  SYAARWD--------VPPEPLRDYQTVDLGQTHLANPGWTTRGAPEHREGGTAKRGIHQR 112

Query: 107 WREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASD 166
            R Y  +   TVA+ + P    V + L  A+  P    ++GR++C    P+ L   ++ D
Sbjct: 113 DRHYWANGVMTVAVTVPPGEPNV-ATLAAALRHPARPLFIGRKACLPAAPVLLRVRESDD 171

Query: 167 PQKALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKG 218
               L +                     T          +       +  + 
Sbjct: 172 AYHVLASEPRDPRAAADTRFFEACWPPGTTAPATESRQRQNRTDDRDWRTQA 223


>UniRef50_D0MET6 CRISPR-associated protein Cas5 family n=1 Tax=Rhodothermus marinus
           DSM 4252 RepID=D0MET6_RHOM4
          Length = 252

 Score =  155 bits (392), Expect = 1e-36,   Method: Composition-based stats.
 Identities = 56/226 (24%), Positives = 90/226 (39%), Gaps = 11/226 (4%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L+LR   P+ ++G P  +       +P  S + GLL   LG    +T+ L+ L E +
Sbjct: 1   MEILLLRFDAPLMSFGAPIVDQYGFIQPYPALSMMTGLLANALGYTHAETARLERLQERL 60

Query: 62  QFAVRCDELILDDRRVSVTGL-------RDYHTVLGAREDYRGLKSH-ETIQTWREYLCD 113
           ++AVR D      R      L           T  G  E  +G  +        R+Y  D
Sbjct: 61  RYAVREDRRGQQLRDFQTVDLSQPFLHDERAWTTRGTLETRQGGTASLGIHIRLRDYWAD 120

Query: 114 ASFTVALWL-TPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALL 172
           A +TVAL L  P     +++LE+A+  P    ++GR+ C    PLF+G  +A+D   AL 
Sbjct: 121 AVYTVALTLDPPDEPPTLADLEQALRFPARPLFIGRKPCLPAAPLFIGRVEAADLLDALR 180

Query: 173 NYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKG 218
              P+       +              P+  + R+   R     + 
Sbjct: 181 R-APLDARADRADFYRVWWETGPDDPPPVEGI-RENLRRPVTDRRD 224


>UniRef50_Q1J367 CRISPR-associated protein, CT1976 n=1 Tax=Deinococcus geothermalis
           DSM 11300 RepID=Q1J367_DEIGD
          Length = 232

 Score =  154 bits (388), Expect = 3e-36,   Method: Composition-based stats.
 Identities = 60/229 (26%), Positives = 90/229 (39%), Gaps = 25/229 (10%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+LRL  PMQAWG  +    R T   P++SG+LGL  A LGI R D+    A    +
Sbjct: 1   MATLLLRLVAPMQAWGTRSRFDDRDTEAEPSKSGVLGLCAAALGIDRADSVEHLA---RL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
            F VR D               DYHT         G     T  T R YL DA+F   L 
Sbjct: 58  AFGVRVDR--------EGVAGTDYHTAQ----LRPGNPRTRTDVTRRAYLADAAFWAGLE 105

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPV---- 177
                  ++++L+ A+  P +   LGR++ P + P+  G         AL     +    
Sbjct: 106 ---GDAGLLTDLDAALHNPHWPLSLGRKAFPPSLPICAGPPLEVSLWDALRTAPSLRWRD 162

Query: 178 ---GGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVS 223
                 +  +       L+  A       +P    +R  Y+ +  + V+
Sbjct: 163 DDEPYRLVLDREAVPQPLRAAASPSRRQDVPDGPFARRRYLSRDVLTVT 211


>UniRef50_B4UE71 CRISPR-associated protein Cas5 family n=2 Tax=Anaeromyxobacter
           RepID=B4UE71_ANASK
          Length = 246

 Score =  154 bits (388), Expect = 3e-36,   Method: Composition-based stats.
 Identities = 56/189 (29%), Positives = 81/189 (42%), Gaps = 6/189 (3%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M   LILR   P+ A+G    +     G FP  S + GL+   LG    D   L+AL   
Sbjct: 1   MLDALILRFDAPLLAFGGVAVDNHGEVGDFPGLSMVAGLIANALGYDHRDCDRLEALQRR 60

Query: 61  VQFAVRCDELILDDRRVSV-----TGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDAS 115
           ++ AVR D                  L    T  GA E   G  S  T   +R Y  DA 
Sbjct: 61  LRIAVRRDRSGQRLVDFQTVALGQPFLERGWTTRGAVEGRDGAFSDGTHIRYRAYWADAV 120

Query: 116 FTVALWLTPHAT-MVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNY 174
           +T+A+ L P A    +  +E+A+ +P    +LGR++C  + P+  G  Q      AL ++
Sbjct: 121 YTLAVTLDPPAESPGLDAVERALREPERPLFLGRKACLPSVPILAGRLQIPSLLAALASF 180

Query: 175 EPVGGDIYS 183
           E V  D + 
Sbjct: 181 ERVSKDRWE 189


>UniRef50_Q2FNU0 CRISPR-associated protein, CT1976 n=1 Tax=Methanospirillum hungatei
           JF-1 RepID=Q2FNU0_METHJ
          Length = 225

 Score =  151 bits (381), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 50/214 (23%), Positives = 79/214 (36%), Gaps = 38/214 (17%)

Query: 35  GLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLG---- 90
            +LG++ A LGI+RDD  +   L     F+V   +            ++D+HT+      
Sbjct: 15  AVLGMVAAALGIRRDDEEAQNRLQAGYGFSVMVLQ--------PGIMIQDFHTIQSVHSS 66

Query: 91  ---------AREDYRGLKSHETIQTWREYLCDASFTVALWLTPHA--TMVISELEKAVLK 139
                     R D   L   ETI + REYLCD      +W+         + E+  +   
Sbjct: 67  SLKKMNHVMTRRDEMNLGDSETILSRREYLCDHVSVACVWIRDAESAQFSLEEIAASFRN 126

Query: 140 PRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNY-----------EPVGGDIYS----E 184
           P +  YLGR+SCP   P+     QA   + AL+ +            P    +Y     +
Sbjct: 127 PVFCLYLGRKSCPPALPVHARVIQADSLKSALVQHIEGFDLLNGFRVPDRVSLYFEDGID 186

Query: 185 ESVTGHHLKFTARDEPMITLPRQFASREWYVIKG 218
                  +    RD  +     QF+ R  Y  + 
Sbjct: 187 IGFDDPVMVMKRRDNILSRSRWQFSDRNEYYARI 220


>UniRef50_D1Y486 Crispr-associated protein Cas5 n=1 Tax=Pyramidobacter piscolens
           W5455 RepID=D1Y486_9BACT
          Length = 269

 Score =  151 bits (381), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 64/229 (27%), Positives = 92/229 (40%), Gaps = 36/229 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              LILRL GP+ A+G    +  RPT   P  S + GL+   LG    D   LQ L E +
Sbjct: 1   MDALILRLRGPLMAFGDVAVDEIRPTDLLPGLSEMTGLIANALGWTFQDVEKLQRLQERL 60

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYR------------GLKSHETIQTWRE 109
           + A R D             LRDY T   + ED              G K   T+Q +R 
Sbjct: 61  RLASREDRT--------GVPLRDYQTARLSSEDSLWRTDGIVAERGGGSKGEFTVQRYRH 112

Query: 110 YLCDASFTVALWLTPHAT-MVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQ 168
           Y  DA+ TV + L P      + E+  A+  P    ++GR  CP + P+           
Sbjct: 113 YRADAAVTVLIALDPADEAPALEEIRDALRHPARPLFIGRIGCPPSQPIC---------- 162

Query: 169 KALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIK 217
                +EP G +I   +S+    +  T R        R+ ASR   +++
Sbjct: 163 -----FEPEGREIIHTDSLKDAIMHITPRAPLGAQTKREPASRNKVLVE 206


>UniRef50_Q0BSC7 Putative uncharacterized protein n=1 Tax=Granulibacter bethesdensis
           CGDNIH1 RepID=Q0BSC7_GRABC
          Length = 225

 Score =  151 bits (381), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 58/231 (25%), Positives = 91/231 (39%), Gaps = 35/231 (15%)

Query: 1   MRS--YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRD-DTSSLQAL 57
           M    +L+  LA  + + G+      R +  +PTRS ++GL+GA LGI+RD D S+L  L
Sbjct: 1   MMQQPFLVFGLAASLGSMGELAGHERRGSLIWPTRSAIIGLMGAALGIERDGDFSALDVL 60

Query: 58  SESVQFAVRCDELILDDRRVSVTGLRDYHTVLGARED------------YRGLKSHETIQ 105
           S  V                +   LRDYHT+                          T  
Sbjct: 61  SIDVAI------------FDAGAPLRDYHTIETIPSAAAKNPNSRPEALRDARGRTNTAI 108

Query: 106 TWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQAS 165
           T R+Y     + +A+         +  +  A+L+P +T Y+GR+SCPL  P      +A 
Sbjct: 109 THRDYRTSVFYGIAVRGAG-----LERIVAALLEPHFTLYVGRKSCPLAAPTGAKIVEAV 163

Query: 166 DPQKALLNYE---PVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREW 213
             + AL + +        + +   VT         D P+      FA+R  
Sbjct: 164 SAEAALEHLKAPLWRKESVKAHLLVTDDPEGEVVTDVPLDRSSWHFATRRV 214


>UniRef50_B8FDI0 CRISPR-associated protein Cas5 family n=3 Tax=Bacteria
           RepID=B8FDI0_DESAA
          Length = 240

 Score =  148 bits (373), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 65/240 (27%), Positives = 96/240 (40%), Gaps = 29/240 (12%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
            YL++ L  P+Q+WG  +  G R T  FPTRSG+LGLL   LG   +    L  L+   Q
Sbjct: 4   RYLLMWLEAPLQSWGADSKFGRRDTLPFPTRSGVLGLLLCALGASGEQKELLARLAPYGQ 63

Query: 63  FAVRC------DELILDDRRVSVTGLRDYHTVLGAREDYRGLK--------------SHE 102
             + C            ++      LRD+H V  A  D    +                 
Sbjct: 64  TVISCAGGRPGRSGGSPEKIPRQPLLRDFHMVGSAYNDKDPWERLHIPKTNEGKPAVGGG 123

Query: 103 TIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTC 162
              T+R YL DA F V L L P    +  +  +A+  P +  YLGR++C  T  ++ G  
Sbjct: 124 AKLTYRYYLQDARFAVILELPPD---LAEDFAQALQNPVWDIYLGRKNCAPTEFVYQGVF 180

Query: 163 ----QASDPQKALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLP-RQFASREWYVIK 217
                A D   AL+  + +  D              T  D P+   P +++  R   VI+
Sbjct: 181 DSQKDAMDRAAALMEEKELMEDF-RVVDGEHPGEPITLNDVPLQFGPMKKYRDRRVTVIR 239


>UniRef50_A9HLC6 CRISPR-associated protein Cas5 family n=11 Tax=Acetobacteraceae
           RepID=A9HLC6_GLUDA
          Length = 260

 Score =  145 bits (366), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 60/260 (23%), Positives = 86/260 (33%), Gaps = 52/260 (20%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M  +L   +  PM ++G       R     P RS +LGL+ ACLG+ RDD  +  AL+  
Sbjct: 1   MGQFLTFAMVAPMASFGAIAVGERRDGWDRPARSAVLGLMAACLGLTRDDEDAQAALAAD 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHE------------TIQTWR 108
              A+                L DYHT   A        +              TI + R
Sbjct: 61  YGLAI--------LCHAPGKLLTDYHTAQAAPARRNWRPATRAEELAASPGDLATILSRR 112

Query: 109 EYLCDASFTVALWLTPH-ATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDP 167
           +Y        A+W +   A   +  L+ A+ +P +TP LGRRSCP   PL          
Sbjct: 113 DYRMGTWHLGAVWTSGKTARWSLEALQAAMREPVFTPSLGRRSCPAGLPLAPSVTDGVSA 172

Query: 168 QKALLNYEPVGGDIYSEESVTG-------------------------------HHLKFTA 196
              LL+    G +                                           +   
Sbjct: 173 AAVLLDRHRNGPEAGLRIRHDSFRRQFAGASRSGGLLLVLDAVDMAEHGGGHTPLRREIR 232

Query: 197 RDEPMITLPRQFASREWYVI 216
           RD+P+     QF  RE  V+
Sbjct: 233 RDQPLSRRRWQFGLREEAVL 252


>UniRef50_B6B783 CRISPR-associated protein Cas5, Ecoli subtype n=1
           Tax=Rhodobacterales bacterium Y4I RepID=B6B783_9RHOB
          Length = 232

 Score =  144 bits (363), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 63/237 (26%), Positives = 88/237 (37%), Gaps = 39/237 (16%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRD-DTSSLQALSE 59
           M  YLI +L   + A G+      R +   P RS ++G LGA +G++RD D S L AL  
Sbjct: 1   MPEYLIFQLVAAIGAMGEFGGHDRRGSLTLPGRSAVIGTLGAAMGLRRDADFSGLDALGV 60

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLG------------AREDYRGLKSHETIQTW 107
           +V                     RDYHTV               +      +   T  T 
Sbjct: 61  AVA------------SFGKTAPFRDYHTVQTVPSAAVKRPQSRPQALRDAGRKVNTTLTS 108

Query: 108 REYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDP 167
           R+Y  D  F VA+W        ++EL  A+  P +  +LGR+SCPL+ P       A+ P
Sbjct: 109 RDYRADCVFGVAIWGEG-----LAELASALSAPVFQTFLGRKSCPLSAPFDPQIVAAATP 163

Query: 168 QKAL--LNYEPVGGDIYSEESVTGHHLK-------FTARDEPMITLPRQFASREWYV 215
             AL  L   P  G    +  V              T  D  +      F    + V
Sbjct: 164 SAALSQLRLPPWIGAREMDMIVADEGTDLGAPSILETRHDRALDRTLWHFGKGRYAV 220


>UniRef50_B4TTX2 CRISPR-associated protein Cas5 n=15 Tax=Enterobacteriaceae
           RepID=B4TTX2_SALSV
          Length = 241

 Score =  141 bits (355), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 66/235 (28%), Positives = 95/235 (40%), Gaps = 33/235 (14%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M+ YL+ +L  P+ +WG+      R +   PTRS LLGLL A LGI+RD+ + L   +  
Sbjct: 1   MKEYLVFQLYAPLASWGEEASGEIRHSATVPTRSALLGLLAAALGIRRDEEARLNNFNRH 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL------------KSHETIQTWR 108
              AV                LRDYHTV   RE+ +                  T+ + R
Sbjct: 61  YHLAVHAL-------ASQDRWLRDYHTVSAPRENKKYRYYTRRDELTLAPDEVGTLISQR 113

Query: 109 EYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQA---S 165
           EY CD  + VA+  TP A   +SEL +A+L P +  YLGR+SCPL  PL           
Sbjct: 114 EYRCDGYWHVAISATPDAPHSLSELREALLTPHFPLYLGRKSCPLALPLAARLMTGTLKE 173

Query: 166 DPQKALLNYEPVGGDIYSEESV----TGHHLKFTA-------RDEPMITLPRQFA 209
               A+          ++             +           ++P+     QF 
Sbjct: 174 VFTHAVEEISAAELSGFTLREGICYWDDPDEESLVWQQKQHSNNQPVSRQRWQFG 228


>UniRef50_UPI0001B51C2B CRISPR-associated Cas5 family protein n=1 Tax=Streptomyces
           viridochromogenes DSM 40736 RepID=UPI0001B51C2B
          Length = 278

 Score =  139 bits (351), Expect = 5e-32,   Method: Composition-based stats.
 Identities = 68/276 (24%), Positives = 100/276 (36%), Gaps = 72/276 (26%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M S L+LRLAGP+Q+WG       R T   PT+SG+ GL+ A LG+ R D   L AL++ 
Sbjct: 1   MTSVLLLRLAGPLQSWGALARFDRRDTLNRPTKSGVTGLVAAALGLDRADD--LGALTD- 57

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGA-------------REDYRGLKSHETIQ-- 105
           ++FAVR D           T +RD+H V                R   +   + ET    
Sbjct: 58  LRFAVRADR--------PGTAVRDFHIVGSGTYPLRPRDLITDHRRAEKAAAALETSTGP 109

Query: 106 ---------------------------------TWRE-------YLCDASFTVALWLTPH 125
                                            T R+       YL DA+F  A+     
Sbjct: 110 VFGHLAARSVTKWYGAPKEIAPDPKTGVLLAGNTTRDAMMTTRWYLADAAFVAAVE--HP 167

Query: 126 ATMVISELEKAVLKPRYTPYLGRRSCPL----THPLFLGTCQASDPQKALLNYEPVGGDI 181
              ++  +  AV  P+   +LGR+SCP     +  +  GT +      ALL         
Sbjct: 168 DQNLLHRISHAVEHPKRLLWLGRKSCPPSGTISGGVHPGTAETILTTTALLPNATSPQPW 227

Query: 182 YSEESVTGHHLKFTARDEPMITLPRQFASREWYVIK 217
              E+  G        D+P+   P        +  +
Sbjct: 228 AWIEAAPGTPGAAQRTDQPVTYHPEHRTHTARWETR 263


>UniRef50_C5V9N1 CRISPR-associated protein Cas5 n=1 Tax=Corynebacterium matruchotii
           ATCC 14266 RepID=C5V9N1_9CORY
          Length = 223

 Score =  137 bits (346), Expect = 2e-31,   Method: Composition-based stats.
 Identities = 57/234 (24%), Positives = 87/234 (37%), Gaps = 41/234 (17%)

Query: 1   MRSYLILRLAGPMQAWGQPT-FEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE 59
           M   L +RLAGP+Q+W  P        T   PTRSGL+GLL    G  R +         
Sbjct: 1   MTEALYIRLAGPLQSWAGPAITGNFVRTEPRPTRSGLVGLLAGACGYGRGEYPEWLT--- 57

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHT----------------VLGAREDYRGLKSHE- 102
            + F +R D           T + D+HT                 +G R   + L S   
Sbjct: 58  QLHFQIREDN--------RGTLVDDFHTINPRDTEEEFRSRLLLAMGQRPTKKLLNSTPD 109

Query: 103 ----TIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLF 158
               T  T R Y+ D  F V +         +  L + + +P +  YLGR++   + P +
Sbjct: 110 GQGLTAITERTYIADGEFIVQIKAGSREHQEL--LAEKLQQPHFVTYLGRKAFAPSFPFY 167

Query: 159 LGTCQASDPQKALLNYEPVGGDIYSE--ESVTGHHLKFTARDEPMITLPRQFAS 210
           LG    + P   L     VGG+   +           +T    P++    Q+ +
Sbjct: 168 LG----AGPDDTLARIPTVGGEEPKKILRFYALDDYGYTTTTVPVVKDRNQWLT 217


>UniRef50_Q3AA65 CRISPR-associated protein Cas5, Hmari subtype n=1
           Tax=Carboxydothermus hydrogenoformans Z-2901
           RepID=Q3AA65_CARHZ
          Length = 248

 Score =  137 bits (346), Expect = 2e-31,   Method: Composition-based stats.
 Identities = 44/229 (19%), Positives = 81/229 (35%), Gaps = 21/229 (9%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSL---QAL 57
           MR  ++  + GP   + +     +  +  FP R+ L G++ A LG+ +D   SL      
Sbjct: 1   MRKVIVFEIRGPAAHFRKFYTNSSSLSYAFPARTTLAGIIAAVLGLPKDSYYSLLTGNKA 60

Query: 58  SESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAR--EDYRGLKSHETIQTWREYLCDAS 115
             +++      +++   + V    L++ +   G         L        +R Y     
Sbjct: 61  HYALRLMTPVRKIMQTVKFVRTKTLKEVNGSGGPTMIPTEIILPVRGRELIYRVY----- 115

Query: 116 FTVALWLTPHATMVISELEKAV-LKPRYTPYLGRRSCPLTHPL---FLGTCQASDPQKAL 171
                           EL K + L P++  YLGR            F GT   ++    +
Sbjct: 116 ------FYHDDPSFQEELAKQLALGPKFPVYLGRSEFLAKIDFLGVFPGTALETNFVDTV 169

Query: 172 LNYEPVGGDIYSEESVTGHHLKFTARDEPMITLP-RQFASREWYVIKGG 219
           +N E +  +     ++ G  L++     P    P R  AS    V + G
Sbjct: 170 VNLELLKDEELLFSTLHGEDLRYLKEKMPFSFNPDRSIASTASVVYEIG 218


>UniRef50_B5GY62 Crispr-associated protein (Fragment) n=1 Tax=Streptomyces
           clavuligerus ATCC 27064 RepID=B5GY62_STRCL
          Length = 260

 Score =  134 bits (338), Expect = 2e-30,   Method: Composition-based stats.
 Identities = 59/186 (31%), Positives = 82/186 (44%), Gaps = 28/186 (15%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
            L+LRLAGP+Q+WG  +   +R TG  PT+SG++GLL A     R   + ++ L  +++ 
Sbjct: 85  VLLLRLAGPLQSWGSASAFNSRQTGAEPTKSGVIGLLAAA--DGRARGACIEDL-RALRL 141

Query: 64  AVRCDELILDDRRVSVTGLRDYHTVLGARED-------------YRGLKSHETIQTWREY 110
            VR D           T LRDYHT    R                    +  T  T R Y
Sbjct: 142 GVRVDRS--------GTLLRDYHTASDHRGRPLAQAGVGAKGTQRPTSPAKYTQVTTRYY 193

Query: 111 LCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKA 170
           L DA F  AL        ++  L++AV  P +   LGRRSC  + PL LG        + 
Sbjct: 194 LQDAVFLAALA---GPRALLDRLDRAVRAPAFPLALGRRSCVPSLPLALGVHPG-SLGEV 249

Query: 171 LLNYEP 176
           L  +  
Sbjct: 250 LSTHPW 255


>UniRef50_B8IMR2 CRISPR-associated protein Cas5 family n=1 Tax=Methylobacterium
           nodulans ORS 2060 RepID=B8IMR2_METNO
          Length = 273

 Score =  133 bits (335), Expect = 4e-30,   Method: Composition-based stats.
 Identities = 49/215 (22%), Positives = 74/215 (34%), Gaps = 21/215 (9%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M + L+  L  P    G       R +   P RS +LGL+   LGI R D +   AL   
Sbjct: 1   MPAGLVFTLYAPFAGMGDVAVGEERGSFDRPARSAVLGLVAGALGIDRADEAGHAALDRG 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL----------KSHETIQTWREY 110
            + A+R               + DYHTV     D +                T+ + R Y
Sbjct: 61  YRLALRLR--------TPGCLVEDYHTVQAPPVDRKARWATRREALAVAGLNTLVSRRAY 112

Query: 111 LCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKA 170
             D    V + +          L  A+ +P + PYLGR+SCPL  PL     +      +
Sbjct: 113 RADPIVDV-VLIHVDEGPTPEALATALRRPTFAPYLGRKSCPLGLPLRPLWAEGVTRVGS 171

Query: 171 LLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLP 205
           LL    +     + +++                 P
Sbjct: 172 LLA--ALDETFVTHDALDPEPTATVLDVLRRAYDP 204


>UniRef50_B5F422 CRISPR-associated protein Cas5 n=59 Tax=Enterobacteriaceae
           RepID=B5F422_SALA4
          Length = 248

 Score =  133 bits (334), Expect = 5e-30,   Method: Composition-based stats.
 Identities = 69/255 (27%), Positives = 101/255 (39%), Gaps = 39/255 (15%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M  YL+ +L GPM +WG       R +   P+RS LLGLL A LGI+RD+   L A +  
Sbjct: 1   MSQYLVFQLHGPMASWGVDAPGEVRHSHELPSRSALLGLLAAALGIRRDEEERLNAFNRH 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL-----------KSHETIQTWRE 109
            QF        L     +    RDYHTV   +E  +             +    + + R+
Sbjct: 61  YQF--------LLCASGNPRWARDYHTVQMPKEVRKARYFSRREELQDPELLSALISRRD 112

Query: 110 YLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQK 169
           Y  DA + +A+  TP A   +++L+ A+  P +  YLGR+S PL  PL     + S    
Sbjct: 113 YYTDAWWMIAVSATPDAPYTLAQLQAALQHPVFPLYLGRKSHPLALPLAPQLLEGSAADV 172

Query: 170 ALLNYEPVGGDIYSEESV----------TGHHLKFT------ARDEPMITLPRQFASREW 213
               Y        + +             G H   T       RD P+      F  R  
Sbjct: 173 LREAYRWYQDQFNALKLPLPRLQNECWWEGEHDGLTASKILRRRDMPLSRQQWLFGERSV 232

Query: 214 ----YVIKGGMDVSQ 224
               ++ K    +SQ
Sbjct: 233 NQGPWLRKEDACISQ 247


>UniRef50_B0K553 CRISPR-associated protein Cas5, Hmari subtype n=4
           Tax=Thermoanaerobacter RepID=B0K553_THEPX
          Length = 236

 Score =  131 bits (330), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 35/230 (15%), Positives = 69/230 (30%), Gaps = 32/230 (13%)

Query: 6   ILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAV 65
           I  L G    + +     +  T   P R+ + G++ A LG +RD        +E++  AV
Sbjct: 3   IFDLWGKFAHFRKFYTNSSSLTYSVPPRTTVEGMIAALLGYERDTYYEKLN-AENLYVAV 61

Query: 66  R----CDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           R      +++     +  T L + H      +    L   ++   +R Y+          
Sbjct: 62  RKMSKTKKIMQSVNYIKATTLGELHFPKQHTQIPFELLISDSKIRYRFYII--------- 112

Query: 122 LTPHATMVISELEKAV--LKPRYTPYLGRRSCPLTHPL--FLGTCQASDPQKALLN---- 173
                  +  E+++ +    P +  Y G      + P   ++   +      A       
Sbjct: 113 --HKDENIFREIKERLFKKAPVFPLYFG------SAPFSCYIDYVEEVTWDWATSEDFQD 164

Query: 174 -YEPVGGDIYSEESVTGHHLKFTARDEPMITL-PRQFASREWYVIKGGMD 221
            Y  +  D   E  +            P      R       YV +    
Sbjct: 165 IYSVMPSDKIKEIDIKNMKGYLLKERMPRDFGIDRTIKEVTTYVYEDVGH 214


>UniRef50_A7ZDW7 Crispr-associated protein Cas5 n=3 Tax=Campylobacter
           RepID=A7ZDW7_CAMC1
          Length = 236

 Score =  130 bits (327), Expect = 3e-29,   Method: Composition-based stats.
 Identities = 39/200 (19%), Positives = 68/200 (34%), Gaps = 11/200 (5%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            S +  RL G    +  P    +  T   P ++ ++G LGA +G   +D   L  +  SV
Sbjct: 1   MSIVAFRLFGDYAHFSHPATIYSSLTYPVPPKTTIMGFLGAVIG--EEDYFKLSNIQYSV 58

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +   +  +       +      + H   G +         E  Q +RE +C  S+ V L 
Sbjct: 59  KIDRQILKKSFVFNGIKFALSSNMHIEEGYQNAK------EKKQFYRELICSPSYVVFLN 112

Query: 122 LTPHATMVISELEKAVL--KPRYTPYLGRRSCPLTHPLF-LGTCQASDPQKALLNYEPVG 178
           L         ++   +   K  +TPYLG   C        +  C+     ++ +N   + 
Sbjct: 113 LENLEQSYQDKIISNLKEHKTAFTPYLGINFCIADFSWIDIKICEKISQDESFINTFTLM 172

Query: 179 GDIYSEESVTGHHLKFTARD 198
            D   E       L      
Sbjct: 173 DDFVFEGINENAKLTTARMP 192


>UniRef50_C2KP44 Putative uncharacterized protein n=1 Tax=Mobiluncus mulieris ATCC
           35243 RepID=C2KP44_9ACTO
          Length = 245

 Score =  129 bits (325), Expect = 6e-29,   Method: Composition-based stats.
 Identities = 52/212 (24%), Positives = 81/212 (38%), Gaps = 23/212 (10%)

Query: 2   RSYLILRLAGPMQAW-GQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
            + + +RLAGP+Q+W G         T  +PTR  L GL+ ACLG  R          + 
Sbjct: 1   MTSVYIRLAGPLQSWAGAKVSGNISHTQDYPTRGSLEGLVAACLGCPRGKYPLW---FQD 57

Query: 61  VQFAVRCDELILDDRRVSVTGLRD--YHTVLGAREDYRGLKSHE------------TIQT 106
           +QFAVR D            G+RD              G ++              T   
Sbjct: 58  LQFAVRVDSPGRICDDYQTIGVRDEDMQVATRLLTLLTGKRATNRGLAFIPDAQGKTTIV 117

Query: 107 WREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASD 166
            R  L DA F V +    H    + +L++A+  P +  YLGR++     P +LG  + S 
Sbjct: 118 RRTLLADAEFIVQIQCEGH----LEQLDQAISDPTFVSYLGRKAFAPGFPFYLGIGEDSA 173

Query: 167 PQK-ALLNYEPVGGDIYSEESVTGHHLKFTAR 197
                + +   +    Y E+       +  +R
Sbjct: 174 IDTLPVFDKGRLESSYYQEKPEPTAESEIKSR 205


>UniRef50_B6XT64 Putative uncharacterized protein n=2 Tax=Bifidobacterium
           RepID=B6XT64_9BIFI
          Length = 212

 Score =  129 bits (325), Expect = 6e-29,   Method: Composition-based stats.
 Identities = 49/196 (25%), Positives = 76/196 (38%), Gaps = 28/196 (14%)

Query: 39  LLGACLGIQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL 98
           +L +  G  R+D   ++ L   + F VR ++            +RD  T           
Sbjct: 1   MLASAQGRTRED--PIEDLL-GISFGVRVEQ--------RGRVIRDLQTEKSLTRKRNSR 49

Query: 99  K-SHETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPL 157
           K   E   T+R YL DA F VAL        V+  L++A+  P++  YLGRRSCP  +PL
Sbjct: 50  KFDKEMPLTYRYYLADACFLVAL---GADRSVLEMLDEAIHSPKWPLYLGRRSCPPNYPL 106

Query: 158 FLGTCQA-SDPQKALLNYEPVGGDIYSEE----------SVTGHHLKFTARDEPMITLP- 205
            LG      D ++AL +      + Y                      T  D P+     
Sbjct: 107 SLGIHDEYEDIRQALNSETWHASEWYRRRYRYPDLEIVCDAEKGENITTQSDLPLSFSRE 166

Query: 206 -RQFASREWYVIKGGM 220
            R++A+R  +  +   
Sbjct: 167 GRRYANRAVHRYRIPN 182


>UniRef50_Q2RXJ5 CRISPR-associated protein, Cas5e family n=5 Tax=Proteobacteria
           RepID=Q2RXJ5_RHORT
          Length = 249

 Score =  126 bits (317), Expect = 5e-28,   Method: Composition-based stats.
 Identities = 50/210 (23%), Positives = 80/210 (38%), Gaps = 8/210 (3%)

Query: 1   MRSY--LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALS 58
           M  +  LI+ L  P+ A+G    +    T  FP  S L GL    LG +R +    Q L 
Sbjct: 1   MPEHRWLIVHLEAPLLAFGGVAIDNVGVTRDFPAASMLTGLFANALGWRRTEWERHQRLQ 60

Query: 59  ESVQFAVRCDELILD-----DRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCD 113
           + + FA R +           +   ++      T  G  E   G       +  R+Y  D
Sbjct: 61  DRLIFAARRERENPTGVLTDTQNAKLSKTERGWTTWGEPEGRDGASYGAPHRRRRDYHGD 120

Query: 114 ASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTC-QASDPQKALL 172
           AS  VAL L       + +L  A+ +P    ++GR+SC  + PL       A+   +AL 
Sbjct: 121 ASVVVALRLDAAEEPALDDLAAALDRPARPLFIGRKSCVPSRPLRGKEFVVAATAYQALQ 180

Query: 173 NYEPVGGDIYSEESVTGHHLKFTARDEPMI 202
                G D   + +       +   + P+ 
Sbjct: 181 ALRSDGNDRQRDGAAAERRAVWPVGEGPVD 210


>UniRef50_Q6NEQ9 Putative uncharacterized protein n=1 Tax=Corynebacterium
           diphtheriae RepID=Q6NEQ9_CORDI
          Length = 242

 Score =  123 bits (310), Expect = 3e-27,   Method: Composition-based stats.
 Identities = 48/184 (26%), Positives = 71/184 (38%), Gaps = 22/184 (11%)

Query: 1   MRSYLILRLAGPMQAW-GQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE 59
           M     +RL+GP+Q+W G         T   PT S L GLL   LG +R +  +      
Sbjct: 1   MIESAYIRLSGPLQSWAGSVVTGNIVRTEPRPTFSSLRGLLAGALGARRGEWPNWLD--- 57

Query: 60  SVQFAVRCDELILDDRRVSV-TGLRDYHTVLGAREDYRGLKSH-------------ETIQ 105
            V+F VR D   +          L +  T        +G K++              T  
Sbjct: 58  DVEFWVREDRKPIVVNEFQTINPLPEVETFRKRLLIAQGRKANSAKALTFTPDAQGGTSI 117

Query: 106 TWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQAS 165
             R YL D  + V +  + H    + E+E A   P +  YLGR++     P +LG   A 
Sbjct: 118 VNRTYLADGEYLVRVTSSTH----MDEIENAFSSPAFVTYLGRKAFYAEFPFYLGRGSAD 173

Query: 166 DPQK 169
             +K
Sbjct: 174 AFEK 177


>UniRef50_A5D0Y3 Putative uncharacterized protein n=1 Tax=Pelotomaculum
           thermopropionicum SI RepID=A5D0Y3_PELTS
          Length = 242

 Score =  123 bits (309), Expect = 4e-27,   Method: Composition-based stats.
 Identities = 46/224 (20%), Positives = 72/224 (32%), Gaps = 21/224 (9%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
             L+  + G +  + QP    T  T  FP R  + GLL + LG+  DD +    L E   
Sbjct: 4   QVLVFSIKGSLAHFRQPDTTATHATYPFPPRPTIHGLLASVLGLDFDDEAGAAFLHEEHF 63

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWL 122
             +   + +                 +  +    G        T  E +    + V    
Sbjct: 64  VGLSLLKPVRTVCA---------QMSMHGKGFTGGGGDSFNRLTTIELVVSPHYLVYYTG 114

Query: 123 TPHATMVISELEKAVL--KPRYTPYLGRRSCPLTHPLFLGTCQ----ASDPQKALLNYEP 176
           +      + EL + +   +  Y  YLG   C LT P+F G       A   ++ L     
Sbjct: 115 SR-----LGELAERIRTGQSVYHTYLGSAYC-LTFPVFHGLYPLLEVAPGEEEPLPCSSV 168

Query: 177 VGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGM 220
           V   +  E  V        AR  P   +  +F  R   VI    
Sbjct: 169 VPQGVIQEILVEPGGNYAVARALPYRHVGGRFFERTLNVIYEVN 212


>UniRef50_B8IJS9 CRISPR-associated protein Cas5 family n=1 Tax=Methylobacterium
           nodulans ORS 2060 RepID=B8IJS9_METNO
          Length = 253

 Score =  123 bits (309), Expect = 4e-27,   Method: Composition-based stats.
 Identities = 51/244 (20%), Positives = 78/244 (31%), Gaps = 34/244 (13%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           MR +L+L L  P+QAWG    +   P   FP  + + GL+   LG  R D   L+AL E 
Sbjct: 1   MREHLLLLLEAPLQAWGGVLVDAYGPVDEFPAATLVGGLVANALGYDRADWQRLEALQER 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRD---YHTVLGAREDYRGL--KSHETIQTWREYLCDAS 115
           +                    L       T  G  E   G         + +R+Y  D  
Sbjct: 61  LVVGAAVLRRGSTITDNQNAKLEKGDVGWTTRGRPEGRGGGAEAYKSPHRRFRDYHADTL 120

Query: 116 FTVALWLTPHAT-MVISELEKAVLKPRYTPYLGRRSCPLTHPL-FLGTCQASDPQKAL-- 171
             VAL L P      +  +   +  P    +LGR+ C  +  + +    +A    KAL  
Sbjct: 121 ALVALRLDPEDEKPDLDAIAHTLEWPERPLFLGRKPCLPSRSIVWPERMRAETLLKALNL 180

Query: 172 -------------------------LNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPR 206
                                      +    G+  S   V     +    D P+    R
Sbjct: 181 GAAMLVAAESANPKLRLELDAGPWRARWPEREGNAPSSRLVEVCDDRDFRNDVPVGLRRR 240

Query: 207 QFAS 210
           +  +
Sbjct: 241 RVGT 244


>UniRef50_B6IWM3 CRISPR-associated protein, CT1976 family n=1 Tax=Rhodospirillum
           centenum SW RepID=B6IWM3_RHOCS
          Length = 280

 Score =  123 bits (309), Expect = 4e-27,   Method: Composition-based stats.
 Identities = 57/206 (27%), Positives = 82/206 (39%), Gaps = 31/206 (15%)

Query: 4   YLILRLAGPMQAWGQP----TFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE 59
           +L   LA P  AWG           + T   P+RS L GLLGA LG++R   + L  LSE
Sbjct: 7   HLCFTLAAPYGAWGAASQSSATTAWKATELDPSRSALTGLLGAALGLER---AHLGRLSE 63

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGA---------------REDYRGLKSHETI 104
           +++FAVR       D +       DYHT+  A               R    G K    +
Sbjct: 64  ALRFAVRTGIRPTRDPQP------DYHTISRAHRPEGREHWSRFEELRPALAGGKQEGAL 117

Query: 105 QTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQA 164
            + REY     +TVA+     A + +  L +A+  P +  Y GR++C L  P        
Sbjct: 118 LSRREYWSLGLWTVAVATLNPAGVPLDRLAQALRTPHWPLYAGRKACTLGLPPDPEVRTG 177

Query: 165 SDPQKALLNYEPVGGDIYSEESVTGH 190
             P   LL+Y         +  +   
Sbjct: 178 PGPLSVLLDYGW---PWQRKPGLDRP 200


>UniRef50_C0W6U0 CRISPR-associated Cas5 family protein n=1 Tax=Actinomyces
           urogenitalis DSM 15434 RepID=C0W6U0_9ACTO
          Length = 201

 Score =  122 bits (307), Expect = 6e-27,   Method: Composition-based stats.
 Identities = 50/193 (25%), Positives = 76/193 (39%), Gaps = 39/193 (20%)

Query: 39  LLGACLGIQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL 98
           +L A +G +R D   ++ L  S++F VR D+          T LRD+HT           
Sbjct: 1   MLAAAVGRRRTD--PIEDLL-SLRFGVRKDQ--------PGTVLRDFHTARTLDGKQS-- 47

Query: 99  KSHETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLF 158
                  + R YL DA +  A+        ++  L+ AV  P +  YLGRRSCP + PL 
Sbjct: 48  ----MPLSERYYLADAVYLAAIE---GEKTLLEGLDVAVRHPVFPLYLGRRSCPPSQPLS 100

Query: 159 LGTCQASDPQKALLNYEPVGGDIYSEE----------------SVTGHHLKFTARDEPMI 202
           LG   A    +AL +      D +                   +       +T  D P+ 
Sbjct: 101 LGIRHA-SLLQALTDEPWQAADWFRLRQDNSFRAEIVIDAASLAPDERGSGYTTLDSPVS 159

Query: 203 TLPRQ--FASREW 213
             PR+  + +RE 
Sbjct: 160 FDPRRRDYQAREV 172


>UniRef50_C2GEY8 CRISPR-associated protein n=1 Tax=Corynebacterium glucuronolyticum
           ATCC 51866 RepID=C2GEY8_9CORY
          Length = 242

 Score =  121 bits (304), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 48/191 (25%), Positives = 75/191 (39%), Gaps = 37/191 (19%)

Query: 1   MRSYLILRLAGPMQAW-GQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE 59
           M S   +RL+GP+Q+W GQ        T   PT +GL GLL   LG +RD+     +   
Sbjct: 1   MPSSTFIRLSGPIQSWAGQSVSGNFIRTNPIPTLTGLRGLLAGALGARRDEIPEWIS--- 57

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKS------------------- 100
            V+F+VR D+          + + D+ T+    E++   +                    
Sbjct: 58  KVRFSVREDQT--------GSFVDDFQTIGSREEEWDFRRRIAILQGMKARSIKQLSFKP 109

Query: 101 --HETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLF 158
                    R YL +A F V +           E++ A   P +  YLGR++ P   P +
Sbjct: 110 AVGANAVVRRTYLSEAEFIVRVT----DERHTEEIDHAFSSPVFATYLGRKAFPAAFPFY 165

Query: 159 LGTCQASDPQK 169
           LGT       +
Sbjct: 166 LGTGNEDVLHQ 176


>UniRef50_Q1AZD3 CRISPR-associated protein, Cas5h family n=1 Tax=Rubrobacter
           xylanophilus DSM 9941 RepID=Q1AZD3_RUBXD
          Length = 258

 Score =  120 bits (302), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 46/236 (19%), Positives = 75/236 (31%), Gaps = 27/236 (11%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           LI  L G    + +     +  +  FP R+ L GL+   +G +RD  +   +L E  Q A
Sbjct: 7   LIFDLCGAYGMFRKFYTNSSSLSYPFPPRTTLAGLIAGMMGCERDSYAEDLSL-ERCQIA 65

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSH--------ETIQTWREYLCDASF 116
           V     +    +     + + H        + G                  RE      +
Sbjct: 66  VSVITPVRRVMQQVNYVMTEGHVWTKNTGGFDGSSGPIQVPVEWVFPEVGHRELR----Y 121

Query: 117 TVALWLTPHATMVISELEKAVLK--PRYTPYLGRRSCP-------LTHPLFLGTCQASDP 167
            V    T      +  L + +    P Y PYLG   CP             LG  +   P
Sbjct: 122 RVY--ATHEDRGWLKRLAEILEGGVPIYPPYLGMSECPGRVEHVATLEGWGLGHREDELP 179

Query: 168 QKALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVS 223
            + +L  E V G    EE V     +       +    R  A+ +    + G  ++
Sbjct: 180 VRTVLPSEAVSGPPRLEEGVQIVKERI---PLALDERRRLIAAADVLYNRAGPHIT 232


>UniRef50_C8PE23 CRISPR-associated protein Cas5 n=1 Tax=Campylobacter gracilis
           RM3268 RepID=C8PE23_9PROT
          Length = 237

 Score =  115 bits (288), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 31/199 (15%), Positives = 69/199 (34%), Gaps = 11/199 (5%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              +   L+G    +  P    +  T   P ++ ++GLLGA +G    +   L  +  SV
Sbjct: 1   MDIIAFELSGDYAHFSHPATIYSSLTYPVPPKTAIMGLLGAIIG--EMNYFKLNDIGYSV 58

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
             + +  +  +    +        H   G         S E  Q ++E + D  + + + 
Sbjct: 59  ILSSQFRKKTMIFNGIKFALSSSMHIEQG------YQDSSEKKQFYKELIKDPRYVIFVD 112

Query: 122 LTPHATMVISELEKAVL--KPRYTPYLGRRSCPLTHP-LFLGTCQASDPQKALLNYEPVG 178
           L+         +  ++   +  +TPYLG   C      + +  C+    +++ ++   + 
Sbjct: 113 LSALNASYKENIIDSLKAHRCVFTPYLGINFCIADFKYIEIKNCELVHEKESFIDTFVLM 172

Query: 179 GDIYSEESVTGHHLKFTAR 197
            D   +       L     
Sbjct: 173 DDFIFDAQSFDIRLTTARM 191


>UniRef50_A7HLK6 CRISPR-associated protein Cas5, Hmari subtype n=2
           Tax=Thermotogaceae RepID=A7HLK6_FERNB
          Length = 236

 Score =  114 bits (285), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 29/233 (12%), Positives = 65/233 (27%), Gaps = 40/233 (17%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSL---QALS 58
             +L+  + G    + +     +  +   P R+ L G++ A LG +RD    +   Q L+
Sbjct: 1   MEFLVFDIKGKFAHFRKFYTNSSSLSYSIPPRTTLEGIIAAILGFERDSYYEILNAQKLN 60

Query: 59  ESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV 118
             ++ A    ++I     +      + +      +    + +      +R Y        
Sbjct: 61  IGLKKATPTRKIIQTLNYIKAKTPSNVYDPDEHTQIPFEIITSNDKVIYRVY-------- 112

Query: 119 ALWLTPHATMVISELEKAVLKPRYT--PYLGRRSCPLTHPLFLGTCQASDPQKALLNYEP 176
              +      ++ +LE  +   ++   PY G        P  +      D +        
Sbjct: 113 ---VNHVDQTIMEDLEYRLKNNKFCYIPYFG------VAPFNISI----DLKGKFQAEPK 159

Query: 177 VGGDIYSEESV----------TGHHLKFTARDEPMITLPRQFASREWYVIKGG 219
              D     SV              +       P          R    ++  
Sbjct: 160 FSEDFVKVSSVIRRNLISSLKVEEEVILLKEKMPRDFSR----ERTVIEMEDY 208


>UniRef50_B5YBH8 CRISPR-associated protein Cas5, Hmari subtype n=1 Tax=Dictyoglomus
           thermophilum H-6-12 RepID=B5YBH8_DICT6
          Length = 250

 Score =  112 bits (281), Expect = 7e-24,   Method: Composition-based stats.
 Identities = 30/220 (13%), Positives = 68/220 (30%), Gaps = 27/220 (12%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES- 60
              ++  L G M  + +     +  +  FP R+ ++GL+   LG +RD    + +  ++ 
Sbjct: 1   MKVIVFDLLGKMAHFRKFYTNSSSLSYHFPPRTTIVGLIAGLLGYERDTYYEIFSTDKAK 60

Query: 61  VQFAVR--------CDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLC 112
           +   V+            +  +    +   R  HT     E        E    +R    
Sbjct: 61  ITIGVKSPLRKILQVVNYVWAENVKQLNQSRGQHT-QIPLEIIFPQDMKE-DICYR---- 114

Query: 113 DASFTVALWLTPHATMVISELEKAVLK--PRYTPYLGRRSCPLTHPLF-LGTCQASDPQK 169
                  ++       ++ +L+  ++     + PYLG             G  + S   K
Sbjct: 115 -------IFFHHKDEKIMEDLKNKLVNFDFCFPPYLGITEFVGKVDFIGEGMAEISRADK 167

Query: 170 ALLNYEPVGGDIYSEESV--TGHHLKFTARDEPMITLPRQ 207
            L++       I     +       ++     P+     +
Sbjct: 168 VLIDSVVSVDYIKKNSLILEPQVGAQYVKEKMPLSFNKDR 207


>UniRef50_D1N0K0 Putative uncharacterized protein n=1 Tax=Victivallis vadensis ATCC
           BAA-548 RepID=D1N0K0_9BACT
          Length = 239

 Score =  108 bits (271), Expect = 1e-22,   Method: Composition-based stats.
 Identities = 38/228 (16%), Positives = 67/228 (29%), Gaps = 35/228 (15%)

Query: 2   RSYLILRLAGPMQAWGQP--TFEGTRPTGRFPTRSGLLGLLGACLGI--QRDDTSSLQAL 57
            S LI  LAG M  W     +       G  P    L G++GA LG    R   +     
Sbjct: 1   MSILIFELAGEMAMWRNVYESMGSYSCLGPAPGN--LAGVIGAALGFASPRSQAAEKPDA 58

Query: 58  SESVQFAVRCDELILDDRRVSVTGLRDYHT---VLGAREDYRGLKSHETIQTWR------ 108
            +   +        +    ++     D+H     +G          +   +  R      
Sbjct: 59  KQLKNWDKAGLPWPVSPELLAWEETNDFHVACRWIGKFPKRVPWNINGCKEINRSDNLRL 118

Query: 109 --EYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSC------------PLT 154
             + + D ++ VA+ L  +       +  A+ KP +   LG   C               
Sbjct: 119 QQQVILDPAYEVAVALPAYEA---ERVAAALRKPAFPLCLGASFCRAIVRNVRIEDAVPE 175

Query: 155 HPLFLGTCQASDPQKALLNYEPV--GGDIYSEESVTGHHLKFTARDEP 200
            P +          +A      +   G  +      G+ +  T  D+P
Sbjct: 176 SPFWAFRTDGGALGEATPFSRHIVNPGSCFERIRSDGYWIYPTP-DQP 222


>UniRef50_O27159 Putative uncharacterized protein n=1 Tax=Methanothermobacter
           thermautotrophicus str. Delta H RepID=O27159_METTH
          Length = 269

 Score =  106 bits (264), Expect = 8e-22,   Method: Composition-based stats.
 Identities = 24/154 (15%), Positives = 47/154 (30%), Gaps = 11/154 (7%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L + +  P   +  P       T     +S + G+L    G  R     +  +S S+
Sbjct: 1   METLAVEIFQPFAQFRNPFTFDYAQTYPLSPKSTVTGMLQNATG--RYYDQDISEISVSI 58

Query: 62  QFAVRCDELILDDRRVSVTGLRDYH-----TVLGAREDYRGLKSHETIQTWREYLCDASF 116
              +           +       YH             Y   K  +   ++++ L +  +
Sbjct: 59  H-GLFESTFWNYQSFIVGDIALKYHHNKLKLWNKGYPLYSVNKKSQRSPSYQQELFNGHY 117

Query: 117 TVALWLTPHATMVISELEKAVLKPRYTPYLGRRS 150
            + L        +I E+  ++ KP     LGR  
Sbjct: 118 YIFLR---GDDDIIEEVCDSLRKPTKPLSLGRSE 148


>UniRef50_B9MPU1 CRISPR-associated protein Cas5, Hmari subtype n=2 Tax=Clostridia
           RepID=B9MPU1_ANATD
          Length = 250

 Score =  105 bits (263), Expect = 9e-22,   Method: Composition-based stats.
 Identities = 33/230 (14%), Positives = 70/230 (30%), Gaps = 18/230 (7%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             +L+  L G    + +     +  +   P R+ + G++ A LG +RD    + + +E++
Sbjct: 1   MKFLVFDLKGKFAHFRKFYTNSSSLSYLVPPRTVIEGMVAAILGFERDSYYDMFS-AENL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLC--DASFTVA 119
             AV+       ++   +    +Y       E        +      E L   +      
Sbjct: 60  LVAVQ-----KLEKTYKIVQTVNYIKAQTISELKNPNTHTQVPL---EILAGYNGFVGFR 111

Query: 120 LWLTPHATMVISELEKAVLK--PRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPV 177
           +++ P    + S L   +      +  Y G           LG  +A   + +      V
Sbjct: 112 VFVMPKDEKIYSFLRARLESGKSEFPIYFGSAPFAAKIEF-LGEFEACRWEDSRAGILTV 170

Query: 178 GGDIYSEE---SVT-GHHLKFTARDEPMITLPRQFASREWYVIKGGMDVS 223
                 +    S+     L       P      +FA++    I       
Sbjct: 171 LDTGLIKSLNLSLEFSSSLALMKDRMPCDFDKDRFATKVKTYIHDENLNP 220


>UniRef50_C7P9L3 CRISPR-associated protein Cas5 n=2 Tax=Methanocaldococcus
           RepID=C7P9L3_METFA
          Length = 258

 Score =  105 bits (263), Expect = 9e-22,   Method: Composition-based stats.
 Identities = 23/170 (13%), Positives = 50/170 (29%), Gaps = 27/170 (15%)

Query: 2   RSYLILRLAGP-MQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
              L  R  G    ++ +P       T + P  + + GL+   LG+ RD           
Sbjct: 1   MWGLKFRCEGIYFVSFRKPVTTSLSLTYKLPPFTAIRGLIANALGMPRDSFEIQNWFKIG 60

Query: 61  VQFAVRCDELILDDRRVSVTGLR--------DYHTVLGAREDYRGLKSHETIQT------ 106
           ++   + +      + + +   +         +  +  ++         E +        
Sbjct: 61  MRVEGKIEIGREMAKFLKMISRKSCYRCENCRFEKIADSKPKKCPNCGKENLVKVEKMIY 120

Query: 107 ---------WREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLG 147
                     RE+L    + + L         I ++  A+  P    YLG
Sbjct: 121 ERAFPSSPMHREFLIMPKYWIYLV---GEEKKIKKIYYALKSPERPLYLG 167


>UniRef50_C7NNV3 CRISPR-associated protein Cas5, Hmari subtype n=3
           Tax=Halobacteriaceae RepID=C7NNV3_HALUD
          Length = 264

 Score =  104 bits (260), Expect = 2e-21,   Method: Composition-based stats.
 Identities = 36/212 (16%), Positives = 63/212 (29%), Gaps = 15/212 (7%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSL--QALSES 60
             L   + GP   + +      + T R   R+ + GL+ A LGI RD    L    +S  
Sbjct: 19  RCLSFEIRGPWGHFRRVEGNVVKQTYRIVPRTTVAGLIAAVLGIDRDGYYDLFGPEVSAI 78

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWR---EYLCDASFT 117
               V     +        T   D  T L  R        + T    +   E L D ++ 
Sbjct: 79  AIQPVEELRTVNMPMNTLSTAAGDL-TSLNPRGKISIKLPNPTKLRQQHNYEVLVDPAYR 137

Query: 118 VALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPV 177
           + + L         +L + +         G+     +  L     +     +  +   P 
Sbjct: 138 IDVALADDERY--EQLRETLAA-------GKSHYVPSLGLSEYLAEIDYLGEFDVKPGPA 188

Query: 178 GGDIYSEESVTGHHLKFTARDEPMITLPRQFA 209
            G I  + +V           E    + +  A
Sbjct: 189 SGTIAVDSAVPDAMDDVVLDPETRCQIEQSPA 220


>UniRef50_D1CHV1 CRISPR-associated protein Cas5 n=1 Tax=Thermobaculum terrenum ATCC
           BAA-798 RepID=D1CHV1_THET1
          Length = 264

 Score =  104 bits (259), Expect = 3e-21,   Method: Composition-based stats.
 Identities = 34/231 (14%), Positives = 63/231 (27%), Gaps = 44/231 (19%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQR-----DDTSSLQAL 57
             +I  LAG    + +     +  +  FP R+ L GL+   +G +R          L   
Sbjct: 4   KMIIFDLAGAYAMFRKFYTNSSSLSYPFPPRTVLAGLIAGIMGYERQGHRNTYAEHLAPG 63

Query: 58  SESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLK-------------SHETI 104
              +  +VR    +    +     + + +        + G +             S    
Sbjct: 64  VADIALSVRV--PVRRVMQTVNYVMTEGNVWSRNAGGFDGSRERTLTPVEWVFPASGRRQ 121

Query: 105 QTWREYLCDASFTVALWLTPHATMVISELEKAVLK-PRYTPYLGRRSCPL-------THP 156
             +R YL           T      +      +     Y PYLG   CP           
Sbjct: 122 LRYRVYL-----------THRDEGWLERFAGYLRSGAVYPPYLGMTECPAVIEPVAEVED 170

Query: 157 LFLGTCQASDPQKALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQ 207
             LG  +   P   ++N      D   +  +     +      P+     +
Sbjct: 171 WELGVREEVLPISTVIN-----ADKIVDLPLPDADAQIVKERMPIALDNDR 216


>UniRef50_Q2NH81 Putative uncharacterized protein n=1 Tax=Methanosphaera stadtmanae
           DSM 3091 RepID=Q2NH81_METST
          Length = 235

 Score =  103 bits (257), Expect = 4e-21,   Method: Composition-based stats.
 Identities = 29/158 (18%), Positives = 55/158 (34%), Gaps = 10/158 (6%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + ++  + G    + +     +  T  FP+R+ + G +   LG  R+    L    E+ 
Sbjct: 1   MNLIVFDIWGDYAYFRRGYTTTSTLTYPFPSRTTIAGFIAGILGYPRNSYYDL-FQKENS 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +  ++    I   R          +T               T     E+L +  + + L 
Sbjct: 60  KIGLKIINPIKKTRINLNYI----NTKNSMLLSEIKGNGKRTQVPA-EFLKNVKYRIYLS 114

Query: 122 LTPHATMVISELEKAVL--KPRYTPYLGRRSCPLTHPL 157
           L      ++++L   +   K  YTPYLG   C     L
Sbjct: 115 L--DDEEIMNKLYNTLKEHKSVYTPYLGITECLANFSL 150


>UniRef50_B5IGN1 CRISPR-associated protein Cas5 n=1 Tax=Aciduliprofundum boonei T469
           RepID=B5IGN1_9EURY
          Length = 236

 Score =  100 bits (248), Expect = 5e-20,   Method: Composition-based stats.
 Identities = 26/148 (17%), Positives = 53/148 (35%), Gaps = 17/148 (11%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGI-QRDDTSSLQALSES 60
              L  +L     ++ +        T   P  + ++GLLG+ LG+  R+  +    L++ 
Sbjct: 1   MEVLTAKLRAISVSFRRILDFNYHRTYPLPPPTTIVGLLGSALGLSDRELWNEYNGLND- 59

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           + FAV                 +D  ++   +      +S      +RE L    +   +
Sbjct: 60  ISFAVLSLR--------KPGFAKDMWSIQKIKNGRISERSPY----FRELLFYPEY---V 104

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGR 148
            +    +  +  +  A+  P Y   LGR
Sbjct: 105 LIFNGDSKSLECVRDALNNPEYALSLGR 132


>UniRef50_UPI0000F51765 hypothetical protein Faci_00030 n=1 Tax=Ferroplasma acidarmanus
           fer1 RepID=UPI0000F51765
          Length = 237

 Score = 97.4 bits (241), Expect = 3e-19,   Method: Composition-based stats.
 Identities = 19/149 (12%), Positives = 52/149 (34%), Gaps = 21/149 (14%)

Query: 1   MRSYLILRL--AGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALS 58
           M+   ++R+   G + ++  P       T   P ++ ++G++ A +G  RDD   +++L 
Sbjct: 1   MKEIKLIRINAYGIINSFRIPLHMTIHDTLDLPVKTHIIGMIAAAMGYLRDDKEKIESLY 60

Query: 59  ESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV 118
           ++    +           + +   +     +         K++              +T+
Sbjct: 61  KNTSIGIYGTSYSKFYDLIRIYKYKGKEVEVSLVNRQINYKNN--------------YTI 106

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLG 147
            +         + E+   +  P +   LG
Sbjct: 107 YI-----ENNNLEEIYNFLKNPVFALSLG 130


>UniRef50_A3XI99 Putative uncharacterized protein n=1 Tax=Leeuwenhoekiella
           blandensis MED217 RepID=A3XI99_9FLAO
          Length = 243

 Score = 97.0 bits (240), Expect = 4e-19,   Method: Composition-based stats.
 Identities = 33/231 (14%), Positives = 68/231 (29%), Gaps = 23/231 (9%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQ--RDDTSSLQALSE 59
               I+ +     ++  P F+    +   P  + ++G+ GA LG    R      ++  E
Sbjct: 1   MKNFIIEIQCQTASFRNPDFQNFHKSLELPPPTTVIGIAGAALGYSPLRAQEFFDESKFE 60

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
              +     +     +      +RD                 +     RE+L   +F +A
Sbjct: 61  IGIYGTYLGKCKDTWKYNKG--IRDM---------RLYDPGLDGSIIQREFLIFPTFIIA 109

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLT---HPLFLGTCQASDPQKALLNYEP 176
              +      + +L KA   P Y   +G      +     + L   +A   +   +  + 
Sbjct: 110 --FSSENIKAVEKLYKAFTSPVYALTMGNSDSLASIKNIEINLEISEADKIENCFVQGDV 167

Query: 177 VGGDIYSEESVTGHHLKFT----ARDEPMITL-PRQFASREWYVIKGGMDV 222
           V   +    S       +T      D P+       +  R    I     +
Sbjct: 168 VNEVMSLANSGNFEFSIYTNDTLTYDLPIRFEYENDYGRRTVSKIDTYSLI 218


>UniRef50_C1DUR1 Crispr-associated protein Cas5, hmari subtype n=1
           Tax=Sulfurihydrogenibium azorense Az-Fu1
           RepID=C1DUR1_SULAA
          Length = 229

 Score = 96.3 bits (238), Expect = 7e-19,   Method: Composition-based stats.
 Identities = 35/209 (16%), Positives = 73/209 (34%), Gaps = 19/209 (9%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L+  + G    + +     +  T   P  + + G++GA LGI + D   +   +E+ 
Sbjct: 1   MEVLVFDVWGDFGHFRKFYTTTSPLTFSIPPPTAVFGIIGAILGIDKKDYLKIIN-AETT 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           + A+   + +   R           T+          +         E+L DA + + + 
Sbjct: 60  KVAIEIVKPVKKIRF----------TINYIDTKVSFSRIKNRTPIRTEFLKDAHYRLYIN 109

Query: 122 LTPHATMVISELEKAV--LKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKA-LLNYEPVG 178
           L  +   +  EL+  +   K  YT  LG  +       ++G  Q      +  +N     
Sbjct: 110 L--NEENLFRELKDRIKERKTYYTVSLGLANLIANFK-YIGQYQVEPLDASNYVNTVISS 166

Query: 179 GDIYSEESVTGHHLKFTARDEPMITLPRQ 207
            +I + E V G   ++     P+     +
Sbjct: 167 ENIENIEMVEGK--RYFKEKMPVDIDENR 193


>UniRef50_B7R550 CRISPR-associated protein Cas5 n=1 Tax=Thermococcus sp. AM4
           RepID=B7R550_9EURY
          Length = 275

 Score = 96.3 bits (238), Expect = 7e-19,   Method: Composition-based stats.
 Identities = 31/202 (15%), Positives = 59/202 (29%), Gaps = 21/202 (10%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACL----GIQRDDTSSLQALS 58
             L++ L  P   +  P       T   P +S ++G+L   L    G +R          
Sbjct: 4   KTLLIELFQPFAQYRNPFTFYYAQTYPLPPKSTIIGMLQNALNDWYGNERGIDEWWN--- 60

Query: 59  ESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL------KSHETIQTWRE-YL 111
             ++ +V      +      +         +        L           + + R   L
Sbjct: 61  --LRVSVHGGFESVFWNYQQLIKATKTGISIVRFRGKPTLWNQKLPLYGFPVTSQRSPVL 118

Query: 112 CDASFTVALW-LTPHATMVISELEKAVLKPRYTPYLGRRS---CPLTHPLFLGTCQASDP 167
               F   L+ L       +SE+++A+ +PR    LGR      P       G    +  
Sbjct: 119 QQELFNGWLYILLKGEEEFLSEIKEALERPRKVISLGRSEDVVFPRRAEFIEGKKDEARE 178

Query: 168 QK-ALLNYEPVGGDIYSEESVT 188
                  Y  V  ++  ++   
Sbjct: 179 IGIKYPTYVRVPIEMLRKKEYP 200


>UniRef50_A3DKB9 CRISPR-associated protein Cas5, Hmari subtype n=2 Tax=Clostridium
           thermocellum RepID=A3DKB9_CLOTH
          Length = 237

 Score = 95.5 bits (236), Expect = 1e-18,   Method: Composition-based stats.
 Identities = 32/223 (14%), Positives = 71/223 (31%), Gaps = 22/223 (9%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
            YL+  ++     + +P    +  T   PTR+ + G++ A LG  ++D        ++ +
Sbjct: 4   KYLVFDISASYGHFKKPYTTTSPLTYSIPTRTAVSGIIAAVLGFGKEDYQEHFTKPQA-K 62

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWL 122
            A+     +   R                         HE  Q   E+L DA + +    
Sbjct: 63  IAIGIRNPVKKVRISEN----------LINTKKSMNIIHERTQIKIEFLKDACYRIY--F 110

Query: 123 TPHATMVISELEKAVL--KPRYTPYLGRRSCPLTHPLFLGT--CQASDPQKALLNYEPVG 178
           T     +   L++++   +  YT  +G       +         +    ++ +     V 
Sbjct: 111 THTDKQIYERLKESLKEHRTVYTISMGLSENLANYTFTGEFDGREVKGNKEIVEFSSVVP 170

Query: 179 GDIYSEESVT-GHHLKFTARDEPMITLPRQFASREWYVIKGGM 220
            DI  +  +      ++     P+       A R     +  +
Sbjct: 171 LDILKKGDIEFEDDREYFTETIPVEMD----AERNINEYREVL 209


>UniRef50_C6QNG6 CRISPR-associated protein Cas5, Hmari subtype n=1 Tax=Geobacillus
           sp. Y4.1MC1 RepID=C6QNG6_9BACI
          Length = 244

 Score = 95.5 bits (236), Expect = 1e-18,   Method: Composition-based stats.
 Identities = 28/157 (17%), Positives = 50/157 (31%), Gaps = 25/157 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              LI  L G M  + +     +  +  FP R+ ++G++   LG++RD    + +  +  
Sbjct: 1   MKMLIFDLIGKMGHFRKIDTNSSSLSYAFPPRTTIVGMIAGILGMERDSYYEVFS-PDQC 59

Query: 62  QFAVRCDELILDDRRVSVTGLRD---------YHTVLGAREDYRGLKSHETIQTWREYLC 112
           Q A+     I    +                  HT     E        E    +R Y  
Sbjct: 60  QIAISVRTPIRKVMQTVNYMFVKSKAHLNNSGGHT-QIPLEFVLPG-GEEANLRYRIY-- 115

Query: 113 DASFTVALWLTPHATMVISELEKAVLKP--RYTPYLG 147
                     +     V   +++ +      Y PYLG
Sbjct: 116 ---------FSHSDRSVYESVKERIQSGRYVYPPYLG 143


>UniRef50_A4J1X9 CRISPR-associated protein Cas5, Hmari subtype n=1
           Tax=Desulfotomaculum reducens MI-1 RepID=A4J1X9_DESRM
          Length = 242

 Score = 94.7 bits (234), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 31/151 (20%), Positives = 61/151 (40%), Gaps = 9/151 (5%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDD-TSSLQALSE 59
           M   +  RL+G    + +     +  +   P R+ LLG+LGA LG+++D     L+ L  
Sbjct: 1   MMKLIAFRLSGRFGHFLRAEAGTSALSYPVPPRTVLLGILGAVLGLEKDLPQELLEPLHI 60

Query: 60  SVQFAVRCDELILDD-RRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV 118
           ++   V          R+     L     V   ++  +  K        +E+L + ++T+
Sbjct: 61  ALAGPVPQSHWHKAKLRKDPPEALP--QVVKNNQKQEKTTKPEMATLITQEWLFNPAYTI 118

Query: 119 ALWLTPHATMVISELEKAVLKPRY--TPYLG 147
            + L         +LE+ + +  +   P LG
Sbjct: 119 WVALP---EPYHQQLEQRLKERCWHFQPCLG 146


>UniRef50_A0LM54 Putative uncharacterized protein n=1 Tax=Syntrophobacter
           fumaroxidans MPOB RepID=A0LM54_SYNFM
          Length = 210

 Score = 94.7 bits (234), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 36/183 (19%), Positives = 67/183 (36%), Gaps = 32/183 (17%)

Query: 59  ESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV 118
            +++  VR D              +D+ T         G  S   + + R +L DA+F V
Sbjct: 32  AALRMGVRVDR--------EGLLRKDFQTAQNVIVA--GGGSVGDLVSNRYFLSDAAFLV 81

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFL--GTCQASDPQKALLNYEP 176
            L       M++  L  ++  PR+  +LGR+S   + P ++  G  + ++   AL ++ P
Sbjct: 82  GLE---GDFMLLHRLHASLAHPRWPVFLGRKSYVPSIPPYIKNGLLEGAELMSALASFTP 138

Query: 177 V---GGDIYSEESVTGH--------------HLKFTARDEPMITLPRQFASREWYVIKGG 219
           +          + V                       RD+PM     Q    + +V+   
Sbjct: 139 LISVEELAARRKRVESGRRVERTRFVLESASPTHEIRRDQPMSFALGQRVFHDRFVVTEY 198

Query: 220 MDV 222
           +DV
Sbjct: 199 LDV 201


>UniRef50_O57910 Putative uncharacterized protein PH0171 n=1 Tax=Pyrococcus
           horikoshii RepID=O57910_PYRHO
          Length = 227

 Score = 94.3 bits (233), Expect = 3e-18,   Method: Composition-based stats.
 Identities = 32/218 (14%), Positives = 67/218 (30%), Gaps = 25/218 (11%)

Query: 1   MRSYLILRLAG-PMQ-AWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALS 58
           M   L L +   P+Q  +  P       T  FP ++  +G+L  C+G+        + L 
Sbjct: 1   MSELLGLIVDARPLQAHFRIPHTSLLLDTYPFPPKTTAVGMLAGCMGLG---EEGFKKLL 57

Query: 59  ESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV 118
           E +++ V  +             + +   +              +    R  L    F +
Sbjct: 58  EKIKYGVIIE--------DPGEKIEEVSVIYK-------NPYSPSYPITRVSLYKPRFRM 102

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGRRS--CPLTHPLFLGTCQASDPQKALLNYEP 176
                     VI E  + +L P++ PY+G            ++      + ++ +L    
Sbjct: 103 FFA---GEERVIEEAYEGLLDPKFVPYMGDSESLFYPGKKRYVEVVDVQEGKEDILRSVI 159

Query: 177 VGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWY 214
                     +    L     + P+    +  + R  Y
Sbjct: 160 PEVKFKEFVPLRRKVLVPKVYEAPVKFTYKGKSRRAVY 197


>UniRef50_B1LAM2 CRISPR-associated protein Cas5, Hmari subtype n=2 Tax=Thermotoga
           RepID=B1LAM2_THESQ
          Length = 220

 Score = 93.2 bits (230), Expect = 5e-18,   Method: Composition-based stats.
 Identities = 32/170 (18%), Positives = 60/170 (35%), Gaps = 23/170 (13%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L+  ++     + +P    +  T  FP R+ LLGL+G  LG        L +   +V
Sbjct: 1   MKVLVFDVSTSYALFRRPYTTTSSYTLPFPPRTALLGLVGCVLGY--STPEKLDSAKVAV 58

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           Q             +  +  LR   T     E  +  K+ +  +   + L + ++ V   
Sbjct: 59  QI------------KNPLKFLR---TGTNFVETKKDKKASKRTRISLQLLKNPAYRVFFS 103

Query: 122 LTPHATMVISELEKAVLK--PRYTPYLGRRSCPLTHPLFLGTCQASDPQK 169
                      L+  +      +TPYLG  S       ++G  +A+  + 
Sbjct: 104 WEDKD---FERLKNLLEHNETIFTPYLGVASFIAKLD-YVGEYEATRVED 149


>UniRef50_B8CYA3 CRISPR-associated protein Cas5 n=1 Tax=Halothermothrix orenii H 168
           RepID=B8CYA3_HALOH
          Length = 238

 Score = 92.8 bits (229), Expect = 7e-18,   Method: Composition-based stats.
 Identities = 28/206 (13%), Positives = 65/206 (31%), Gaps = 19/206 (9%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
             L+ ++ G +  + +     +  T + P R+ L+G++ + L   RD    L +  ++ +
Sbjct: 5   QVLVFKIKGKIAHFKKYYSNKSSLTYKIPPRTVLMGIVASILEKPRDSYYELLSPQQA-K 63

Query: 63  FAVRCDELILDDRRVSVTGLRD-YHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           F V+ +               D  HT    +   + L     + +++ +           
Sbjct: 64  FGVKIESESYTHFECMNYLKEDGGHT----QVRLQLLLPANNMLSYKVF----------- 108

Query: 122 LTPHATMVISELEKAVLKPR--YTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGG 179
            T     ++ EL   +      Y  YLG+R    T             +    N + +  
Sbjct: 109 FTHQDESLLKELATKIKNKIYGYGIYLGQRQFRATAEFDDLIEDIDIIKDYTGNLKTLTY 168

Query: 180 DIYSEESVTGHHLKFTARDEPMITLP 205
               ++            + P+    
Sbjct: 169 KDNIKKLNDTTTYNLILDNMPVSFKK 194


>UniRef50_A7BQN4 Protein containing DUF522 n=1 Tax=Beggiatoa sp. PS
           RepID=A7BQN4_9GAMM
          Length = 267

 Score = 92.8 bits (229), Expect = 8e-18,   Method: Composition-based stats.
 Identities = 31/161 (19%), Positives = 62/161 (38%), Gaps = 14/161 (8%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALS-ES 60
              ++  ++G    + +P    +  T  FP  + ++GLLGA LG  +++    + L  ++
Sbjct: 22  MRCIVFDISGEYAHFKKPYSPMSPVTYPFPPPTAIMGLLGAILGYSKEEY--HERLGWQT 79

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHE--TIQTWREYLCDASFTV 118
           ++  +R  +     R           T  G    +R        T   + E++   ++ +
Sbjct: 80  LRVGIRLLKPTQIFRAAINLL----QTKDGTDTFFRPKADKNSHTRVPY-EFVKSPAYRI 134

Query: 119 ALWLTPHATMVISELEKAVL--KPRYTPYLGRRSCPLTHPL 157
            +   P    V S+L   +   +  YTP LG  SC      
Sbjct: 135 YVMQLPD--NVASDLVAHLKTHRTVYTPVLGLASCLADVEW 173


>UniRef50_A3DHS3 CRISPR-associated protein Cas5 n=3 Tax=Clostridium thermocellum
           RepID=A3DHS3_CLOTH
          Length = 241

 Score = 92.0 bits (227), Expect = 1e-17,   Method: Composition-based stats.
 Identities = 37/188 (19%), Positives = 60/188 (31%), Gaps = 19/188 (10%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              LI+ L     ++  P  +    T   P  S + G+ GA LG+  +D     AL+   
Sbjct: 1   MYGLIVTLYAKTASFRDPGAQLYHETMSLPPPSTITGIAGAALGLSFED-----ALAFMK 55

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           + AV        + R       D       +               R +L D    V ++
Sbjct: 56  ENAVMVGCNGSSEGRGK-----DLWNYTKIKSGEITNA-----IIIRNFLADLK--VEIF 103

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASD-PQKALLNYEPVGGD 180
                  VI+ L  A   P Y   LG  S  +     +   +     +K +L    + GD
Sbjct: 104 FACEKREVITRLADAFENPVYAITLG-NSDEIAKICSIEIFEEISCEKKKILTNTWLPGD 162

Query: 181 IYSEESVT 188
              +  V 
Sbjct: 163 YSRKLKVD 170


>UniRef50_C9RCY2 CRISPR-associated protein Cas5, Hmari subtype n=2
           Tax=Thermoanaerobacteraceae RepID=C9RCY2_AMMDK
          Length = 266

 Score = 91.6 bits (226), Expect = 2e-17,   Method: Composition-based stats.
 Identities = 40/221 (18%), Positives = 65/221 (29%), Gaps = 26/221 (11%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE- 59
           M +  +  L GP   + +     +  +  FP R+ L+G + A LG +RD       LSE 
Sbjct: 1   MVNVAVFDLVGPFAHFRKYYTNSSSLSYAFPPRTALMGTVAAVLGWERDSYYEKLGLSEA 60

Query: 60  --SVQFAVRCDELILDDRRVSVT-----GLRDYHTVLGAREDYRGLKSHET--IQTWREY 110
             +V   V    LI     +         LR    V G +     L    T     +R Y
Sbjct: 61  RFAVVIKVPVRRLIQTVNYIRTKEEDLNRLRKLEAVKGTQVPLELLLPGGTASSLCFRVY 120

Query: 111 LCDASFTVALWLTPHATMVISELEKAVL--KPRYTPYLGRRSCPLTHPL--FLGTCQASD 166
                             V  EL + +   +  +  YLG         L  F    +   
Sbjct: 121 -----------FAHRDDQVTRELAERLAAGRSYFPLYLGLTEFIAQARLVDFKPPDEIIP 169

Query: 167 PQKALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQ 207
             + +  +  +  D      + G          P      +
Sbjct: 170 AGQEVELHSVLAADYLRRPVLRGEVA-LNRERAPQSFGAGR 209


>UniRef50_D0MJ68 CRISPR-associated protein Cas5 n=1 Tax=Rhodothermus marinus DSM
           4252 RepID=D0MJ68_RHOM4
          Length = 236

 Score = 90.1 bits (222), Expect = 5e-17,   Method: Composition-based stats.
 Identities = 37/148 (25%), Positives = 57/148 (38%), Gaps = 15/148 (10%)

Query: 3   SYLILRLAGPMQAWGQPTF-EGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             + + LAGP+ ++  P F  G +PT   P  S + GL+ A LG   D         E++
Sbjct: 7   EAVKVELAGPVASFRYPHFLIGRQPTYPMPPPSTIYGLISAALGRFPD--------PEAL 58

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           QFA R +        V        +T        + L++   I   RE+L     T+ + 
Sbjct: 59  QFAYRFECARHRVDDVETIWFVQPNTATRGEAARKNLEATSNILP-REWLVHPRLTLYVT 117

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRR 149
                   +  L +A   P Y   LGR 
Sbjct: 118 GDE-----LEALYRAFRSPCYILTLGRS 140


>UniRef50_D1B1G1 CRISPR-associated protein Cas5 n=1 Tax=Sulfurospirillum deleyianum
           DSM 6946 RepID=D1B1G1_SULD5
          Length = 237

 Score = 90.1 bits (222), Expect = 5e-17,   Method: Composition-based stats.
 Identities = 28/147 (19%), Positives = 54/147 (36%), Gaps = 18/147 (12%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGA-CLGIQRDDTSSLQALSES 60
              +   + G + ++  P F     T   P ++ ++GLL    L  Q++    L    E 
Sbjct: 1   MEAIRFEVEGLLNSFRVPFFRTYHKTFLAPPKTTIIGLLCNIALKSQKEFFEILN--QEL 58

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           +  +V  DE+            +D  +     +   G          R+ L  + +T+ L
Sbjct: 59  IDVSVIIDEING--------KTKDLWSYKTLEKGNMGK-----SVIRRDKLFLSKYTIYL 105

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLG 147
            +      +  E+  A+  P+ TP LG
Sbjct: 106 SIKNK--TLFDEIYSALKNPKNTPALG 130


>UniRef50_B1B9K0 Crispr-associated protein Cas5, tneap subtype n=1 Tax=Clostridium
           botulinum C str. Eklund RepID=B1B9K0_CLOBO
          Length = 244

 Score = 88.6 bits (218), Expect = 1e-16,   Method: Composition-based stats.
 Identities = 24/151 (15%), Positives = 54/151 (35%), Gaps = 11/151 (7%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQ-ALSES 60
              ++L++   +  + +PT    + T   P  S ++G++ A  G   D+   ++ ++  +
Sbjct: 1   MKAILLKVTQNLVNYKKPTSFQLKETYPLPPYSTVIGMVHAACGF--DEYKDMEVSIQGN 58

Query: 61  VQFAVRCDELILDDRRVSVTGLRDY-HTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
               V     +      +     D  H +    ED           +  E L D    + 
Sbjct: 59  YHSKV---NDLYTRYEFAGASYEDKRHNIKLKGEDKYYGAMRG--VSTCELLVDVELLIH 113

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRS 150
           +   P    +I  + + +  P+    +GRR 
Sbjct: 114 I--KPKDENLIQIIYQNLKYPKEYLSIGRRE 142


>UniRef50_A8F3P0 CRISPR-associated protein Cas5, Hmari subtype n=1 Tax=Thermotoga
           lettingae TMO RepID=A8F3P0_THELT
          Length = 230

 Score = 85.9 bits (211), Expect = 9e-16,   Method: Composition-based stats.
 Identities = 28/169 (16%), Positives = 57/169 (33%), Gaps = 22/169 (13%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRD--DTSSLQALSE 59
              ++  + G    + +     +  +  FP R+ + GLLGA +GIQ +    S    + +
Sbjct: 1   MKVIVFDVKGKYALFRRNYTTSSSTSYNFPPRTSICGLLGAIMGIQNEATQFSKHLRIFD 60

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
           +   A+R    I               T +G          ++  Q   E + +  + + 
Sbjct: 61  NAHIALRVLVPIRK-------------TTMGVNYAETKSGKNQRTQIILELIKEPVYRIY 107

Query: 120 LWLTPHATMVISELEKAVLK--PRYTPYLGRRSCPLTHPLFLGTCQASD 166
           +           +L   +      +TPYLG+          +G  +A  
Sbjct: 108 VS----EFSQFDQLRNHLENNTCVFTPYLGQAQFIAKIS-HVGVFEAKS 151


>UniRef50_Q8PZD2 Putative uncharacterized protein n=1 Tax=Methanosarcina mazei
           RepID=Q8PZD2_METMA
          Length = 232

 Score = 85.5 bits (210), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 28/210 (13%), Positives = 61/210 (29%), Gaps = 28/210 (13%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGR--FPTRSGLLGLLGACLGIQRDDTSSLQALSE 59
              L+ R       + +P    +  T     P    + GL+GA LGI + +   +   + 
Sbjct: 1   MDCLVFRAKSGYAKFRKPYTTTSALTFLCIHPP--AVKGLIGAVLGIDKTE---IYRNTL 55

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
            ++  ++    +           +D   +            +  +    E+L D  + + 
Sbjct: 56  DLKIGIQVLSPVR----------KDMQVLKLVSMKAEKDLFNFPV--NAEFLRDPEYRIF 103

Query: 120 LWLTPHATMVISELEKAVLK--PRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPV 177
           +   P     + ELE  +    P +TPYLG          +     A        +    
Sbjct: 104 VSWLPDK---LDELEDRLQNQMPIFTPYLGVSEYIAKLD-YEKRVNAELL---TKSSSID 156

Query: 178 GGDIYSEESVTGHHLKFTARDEPMITLPRQ 207
                    +          + P+    ++
Sbjct: 157 SLVPSRFIDLQHSDYHIFTDNIPVSNNEKR 186


>UniRef50_D2QT47 CRISPR-associated protein Cas5 n=1 Tax=Spirosoma linguale DSM 74
           RepID=D2QT47_9SPHI
          Length = 237

 Score = 84.7 bits (208), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 34/226 (15%), Positives = 60/226 (26%), Gaps = 30/226 (13%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGI-QRDDTSSLQALSES 60
                + L     ++  P F+    +   P  + L+GL GA LG+  R     L      
Sbjct: 1   MLCCTIELKSVTASFRNPEFQNFHKSFPLPPPTALIGLAGAALGLSPRMAQDFLD----- 55

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
                  ++             RD          Y  L    +    RE   +  +   L
Sbjct: 56  ------TNQFQAGVSGKGEGMTRDLW-------KYDRLTGTGSSIILREIYVNPHYR--L 100

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTH---PLFLGTCQASDPQKALLNYEPV 177
                    + +L+ A   P Y   LG+           L     +    +  L+  + V
Sbjct: 101 VFGSDNHEAVEQLKAAFDSPVYALTLGQSDSLAKIVRTTLTDAVVEGQTLENTLVEGDIV 160

Query: 178 GGDIYSEE-----SVTGHHLKFTARDEPMITLPR-QFASREWYVIK 217
              +         S++       A   P     +  +  R     K
Sbjct: 161 PAILEQVLYGGTFSLSLSTSDPIAYQLPTRFNYKADYGMRTVSERK 206


>UniRef50_Q3M7D6 Fruiting body developmental protein S-like protein n=3
           Tax=Cyanobacteria RepID=Q3M7D6_ANAVT
          Length = 210

 Score = 83.2 bits (204), Expect = 7e-15,   Method: Composition-based stats.
 Identities = 21/142 (14%), Positives = 46/142 (32%), Gaps = 17/142 (11%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + + L++  P+  + Q        T   P  S + G+L + +G    +    +     +
Sbjct: 1   MTTIALKVEVPIACFRQSRAREYGETYPVPPPSTVYGMLLSLVG----EVDRYKHCGVKL 56

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
             A+              T +R +H      +      S      ++E L +  F V + 
Sbjct: 57  AIAL-------LSEPEKSTVIRTFH----RFKTKNIHDSKNNKPDYQELLTNIEFIVWVD 105

Query: 122 LTPH--ATMVISELEKAVLKPR 141
                    ++  L +A+  P 
Sbjct: 106 AGVDKAKPNLVERLAEALTNPA 127


>UniRef50_C5CFB1 CRISPR-associated protein Cas5, Hmari subtype n=1 Tax=Kosmotoga
           olearia TBF 19.5.1 RepID=C5CFB1_KOSOT
          Length = 236

 Score = 82.0 bits (201), Expect = 1e-14,   Method: Composition-based stats.
 Identities = 32/174 (18%), Positives = 60/174 (34%), Gaps = 25/174 (14%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE-- 59
              L+L ++     + +P    +  T   P R+ +LG++G+ LGI        +      
Sbjct: 1   MKVLVLDISSDYAHFRKPYTTTSALTYSIPPRTAVLGIIGSILGISSGGFGKSEHSKFFE 60

Query: 60  --SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFT 117
             +V+  VR    I          L+  HT  G       L   E + +         + 
Sbjct: 61  TNNVKTGVRLLTSIKKTTFN----LKYLHTKNGG----SILVPVECVVS-------PIYR 105

Query: 118 VALWLTPHATMVISELEKAVLK--PRYTPYLGRRSCPLTHPLFLGTCQASDPQK 169
           + +         +++LE  V      YTPYLG      +   ++G  +     +
Sbjct: 106 IYVS---GNEDFLAKLESVVKNKECYYTPYLGISEFLASVS-YVGFFEGKRVDE 155


>UniRef50_C8VZL1 CRISPR-associated protein Cas5 n=1 Tax=Desulfotomaculum acetoxidans
           DSM 771 RepID=C8VZL1_DESAS
          Length = 253

 Score = 81.2 bits (199), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 37/232 (15%), Positives = 68/232 (29%), Gaps = 35/232 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              +   L G M  + +     +  +   P R+ L+G++   LG +RD    + +L+ S 
Sbjct: 1   MKIISFHLRGKMAHFRRYYANSSALSYSIPPRTTLIGIVAGLLGWERDKYYEIFSLN-SC 59

Query: 62  QFAV----RCDELILDDRRVSVTGLRDY-----HTVLGAREDYRGLKSHETIQTWREYLC 112
           + AV       + +     + +    D      H    A E          I  ++    
Sbjct: 60  KVAVASCAPVKKCMQKLNLLMIKKAGDLNGSAEHHSQTATELIIPQNIRTGIIDYQ---- 115

Query: 113 DASFTVALWLTPHATMVISELEKAVL-KPRYTPYLGRRSCPLTHPLFLGTCQASDPQKAL 171
                  +WL      ++  L K +  + R    LG  S  L     LG        + +
Sbjct: 116 -------VWLHHRDNKIMDMLGKLLQLEGRGYKSLGI-SLALGTVFNLGWVDDGCIIEGV 167

Query: 172 LNYEPVGGDIYSEESVTG-----------HHLKFTARDEPMITL-PRQFASR 211
              +     I S   V                +    + P+     R    R
Sbjct: 168 EKEKSNDLSIASVIPVKKLIGIQTERMGADEYRLVKEEIPLEFDSQRHITER 219


>UniRef50_B1I4M5 CRISPR-associated protein Cas5 family n=1 Tax=Candidatus
           Desulforudis audaxviator MP104C RepID=B1I4M5_DESAP
          Length = 255

 Score = 78.9 bits (193), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 24/152 (15%), Positives = 52/152 (34%), Gaps = 22/152 (14%)

Query: 2   RSYLILRLAGPMQAWGQPTF-EGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
                + +  P+ ++  P F  G + +   P  S + G + + +G    +  +   +  +
Sbjct: 1   MRVAKVHIEAPIASFRYPHFLIGRQTSFDMPPPSTIYGHIASAVG----EWFNPATVKFA 56

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREY---LCDASFT 117
            QF+           +   + L   H +    + ++  +    + T       L D  F 
Sbjct: 57  YQFS----------FQAKGSDLEHQHVITKGGQTFKWGERKYPVSTQAVVQPHLRDFLFG 106

Query: 118 VALWLTPHATMVISELEKAVLKPRYTPYLGRR 149
             L L  +      +L +A   P +   LGR 
Sbjct: 107 CRLTLYLYPP----DLAEAFRNPVFCVILGRS 134


>UniRef50_B0VIK7 Putative uncharacterized protein n=1 Tax=Candidatus Cloacamonas
           acidaminovorans RepID=B0VIK7_9BACT
          Length = 259

 Score = 78.9 bits (193), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 31/161 (19%), Positives = 55/161 (34%), Gaps = 19/161 (11%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
             L L+L+G    + +     +  T   P R+ + GLL + L I+RD   +L + S+ + 
Sbjct: 9   RILELKLSGKFAHFRKFYTNASSLTYLIPPRTAICGLLASILQIERDCYYNLMS-SDKLG 67

Query: 63  FAVRCDELILDDRRVSVTGLRDYHT---VLGAREDYRGLKSHETIQTWREYL-----CDA 114
            A+     I   +         + T        ++          Q   E L      + 
Sbjct: 68  IAISLVPNIYYHKV--------FQTLNYAQDKSKNIPINDLSAHKQCRLELLKAQGSKNL 119

Query: 115 SFTVALWLTPHATMVISELEKAV--LKPRYTPYLGRRSCPL 153
            + + L          +ELE  +      Y  YLG+R    
Sbjct: 120 EWILYLCFNSAEENNFAELEHKIKEKNFGYGLYLGQRQFIA 160


>UniRef50_B1I5P1 CRISPR-associated protein Cas5 n=2 Tax=Clostridia
           RepID=B1I5P1_DESAP
          Length = 238

 Score = 78.2 bits (191), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 49/215 (22%), Positives = 75/215 (34%), Gaps = 38/215 (17%)

Query: 13  MQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDELIL 72
           M ++ +P     + T   P  + L GL GA  G+   +    Q  S         D L+ 
Sbjct: 1   MASFRRPLDHNYQRTLPLPPPTTLFGLAGAARGL--AEEELWQEASPL------RDLLVA 52

Query: 73  DDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPHATMVISE 132
                     RD  TV+  + +    +S      +RE L +A F +   L      +++E
Sbjct: 53  TLALQKPGLARDMWTVMKIKNNKLAERSPY----FREILFNARFMI---LYGGPEELLAE 105

Query: 133 LEKAVLKPRYTPYLGR-------------RSCPLTHPLFLGTCQASDPQKALLNYEPVGG 179
           L++A L P Y   LGR              +C    PLF GT    D Q     + P  G
Sbjct: 106 LQQAFLDPTYPLSLGREDELIVVEELGRGETC-PGAPLFSGTVIPGDLQGLRFKWVPRPG 164

Query: 180 DIYSEESVTGHHL---------KFTARDEPMITLP 205
             +   +V    L         ++     P   LP
Sbjct: 165 IAFEPPAVETMPLAFEVDKRGIRYPLNPRPFTFLP 199


>UniRef50_A0B6V6 CRISPR-associated protein Cas5, Hmari subtype n=1 Tax=Methanosaeta
           thermophila PT RepID=A0B6V6_METTP
          Length = 233

 Score = 77.0 bits (188), Expect = 5e-13,   Method: Composition-based stats.
 Identities = 27/149 (18%), Positives = 51/149 (34%), Gaps = 19/149 (12%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
           S L+  + G    + +     +  T  FP R+ + G++GA  G+ ++      +  ++  
Sbjct: 4   SVLVFDVWGDYAHFRKIYTTSSPLTYSFPPRTAISGIIGAIAGLSKESYFRYFSRDKA-S 62

Query: 63  FAVRCDELILDDRRVSV--TGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
              R  E +   R         R  H +    +               E+L D  F + L
Sbjct: 63  IGCRILEPVKKVRVGENLIDTKRSMHRIHNRTQVRF------------EFLKDPRFRIYL 110

Query: 121 WLTPHATMVISELEKAVL--KPRYTPYLG 147
             +        +L   +   +  YTP LG
Sbjct: 111 --SHSDDRFSRDLRDMLEDHRCVYTPCLG 137


>UniRef50_UPI0000F51712 CRISPR-associated Cas5 family Hmari subtype protein n=1
           Tax=Ferroplasma acidarmanus fer1 RepID=UPI0000F51712
          Length = 256

 Score = 76.2 bits (186), Expect = 7e-13,   Method: Composition-based stats.
 Identities = 23/152 (15%), Positives = 49/152 (32%), Gaps = 13/152 (8%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
            LI  +     ++ +     +  T  FP R+ L G++GA +G   D          ++  
Sbjct: 1   MLIFDIKAKFASFKKLYTNSSSMTYMFPPRTTLEGIIGAIMGYDFDSYYEKFNFKYTL-I 59

Query: 64  AVRCDELILDDRRVSVT-GLRDYHTVLGAREDYRGLKSHETIQTWREYL-----CDASFT 117
           A     +I           + D       +        + T   +   L      +  + 
Sbjct: 60  ATSLKSIIRTYMTNLNYIKIVDN--NYFIKNIINNNGYNYTQIPFEFLLPENFSKNIIYR 117

Query: 118 VALWLTPHATMVISELEKAV--LKPRYTPYLG 147
           +  +       ++++LE+ +    P Y   LG
Sbjct: 118 IYFFSKDDD--LMAKLEEKIIKNNPVYPVSLG 147


>UniRef50_A6UVX6 CRISPR-associated protein Cas5, Hmari subtype n=2
           Tax=Methanococcales RepID=A6UVX6_META3
          Length = 256

 Score = 75.8 bits (185), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 25/173 (14%), Positives = 58/173 (33%), Gaps = 13/173 (7%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              ++  + G    + +     +  +  FP ++ + G+LGA LG+ ++D        ++V
Sbjct: 1   MKMIVFDIWGDYGHFKKIYTTTSPLSYDFPPKTSIYGMLGAFLGLDKEDYLKHIN-KDTV 59

Query: 62  QFAVRCDELILDDR------RVSVTGLRDYHTVLGAREDYRGLKSHETIQTWR-----EY 110
           + A++    I                ++  +  L  +        +  +   R     E 
Sbjct: 60  KIALKIKNPIQKTNIALNLIDTKRDKIKKSNISLDNKSIKSIKIYNVNLIPNRTQIRFEM 119

Query: 111 LCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQ 163
           L +  + + + LT        +      K  YT  LG          ++G  +
Sbjct: 120 LKNPKYRLYVHLTDEKLYSKLKKLLEQHKTVYTISLGLSELLANFE-YMGEFE 171


>UniRef50_A1ZHZ1 Crispr-associated protein Cas5, hmari subtype n=1 Tax=Microscilla
           marina ATCC 23134 RepID=A1ZHZ1_9SPHI
          Length = 250

 Score = 75.1 bits (183), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 29/168 (17%), Positives = 54/168 (32%), Gaps = 21/168 (12%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQA----- 56
           ++ LI  +      + +     +  T   P R  L+GLLGA +GI+R+ ++         
Sbjct: 4   KTILIFDIESEYGHFRKFNTTTSPLTYPIPPRPALVGLLGAIVGIEREASAGKFNEGVTP 63

Query: 57  -----LSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYL 111
                     + AV+    +             ++ +   +         +  Q   E L
Sbjct: 64  VAELFAKPDTELAVQLINPVKKVPMA-------FNLLDTEKSGASFFNIKQRTQIEFELL 116

Query: 112 CDASFTVALWLTPHATMVISELEKAVLKP--RYTPYLGRRSCPLTHPL 157
               F V +     A  ++  L   +      +TPYLG      T   
Sbjct: 117 KHPCFRVFVACANDA--LMQPLVDNIQHNQAHFTPYLGLSQFTATFNF 162


>UniRef50_C5D4M6 CRISPR-associated protein Cas5, Hmari subtype n=1 Tax=Geobacillus
           sp. WCH70 RepID=C5D4M6_GEOSW
          Length = 245

 Score = 75.1 bits (183), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 25/155 (16%), Positives = 53/155 (34%), Gaps = 10/155 (6%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQAL-SES 60
            + L+  +      + +     +  T      +   G+LGA +G+ +++   L+ +  E+
Sbjct: 1   MNVLVFDIRADFGHFRKIYSTSSPLTYSIIPPTSFFGILGAIIGLGKEENEYLRYVNHET 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           V  A+R    +   R      L   +T        +  +   T     E+L    F   +
Sbjct: 61  VNMAIRVMSPVRKMRIG----LNHVNTKGNVWVPKQRREGARTQIRT-EFLRFPYFRCYV 115

Query: 121 WLTPHATMVISELEKAVL--KPRYTPYLGRRSCPL 153
                   +  +L + V   +  YT  +G   C  
Sbjct: 116 --HVKEQSLFQQLIEYVQQHRSVYTVCMGLSECIA 148


>UniRef50_D1A6P6 Metal dependent phosphohydrolase n=1 Tax=Thermomonospora curvata
           DSM 43183 RepID=D1A6P6_THECD
          Length = 1027

 Score = 73.9 bits (180), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 24/152 (15%), Positives = 41/152 (26%), Gaps = 26/152 (17%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
             + ++L  P+ ++  P F G       P  S L G+L A  G                 
Sbjct: 9   EAVRVQLYAPVASFRDPMFPGVTRCLPVPPPSTLRGMLAAATGRP--------------- 53

Query: 63  FAVRCDELILDDRRVSVTGLRDYH-TVLGAREDYRGLK----SHETIQTWREYLCDASFT 117
            A      +             YH           G +            R +L     T
Sbjct: 54  -AEPVVLGVCAYAEGRGVDTETYHPIAADGSNPAIGGRVRPGKGGMTIRERPFLTGVHIT 112

Query: 118 VALWLTPHATMVISELEKAVLKPRYTPYLGRR 149
           + + +          +  A+ +P +   LGR 
Sbjct: 113 LWVPMPDG-----ERIATALRRPTWGLRLGRS 139


>UniRef50_A9BGY6 CRISPR-associated protein Cas5, Hmari subtype n=1 Tax=Petrotoga
           mobilis SJ95 RepID=A9BGY6_PETMO
          Length = 242

 Score = 73.9 bits (180), Expect = 4e-12,   Method: Composition-based stats.
 Identities = 20/150 (13%), Positives = 53/150 (35%), Gaps = 24/150 (16%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQR--DDTSSLQALSESV- 61
           L+  + G    + +     +  +  FP  + + GL+ A +G++   ++ + L +  E++ 
Sbjct: 3   LVFDITGEYAMFRKFYTTTSSASYPFPPPTAVGGLIAAIIGVENKSENKAHLASYWEALY 62

Query: 62  --QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
             + ++     I             + T +         K    I   + ++    + + 
Sbjct: 63  GNRISISIRSPIKW-----------FTTSINLWNYKDPKKGIHNIIKHQ-FVKRPKYRIY 110

Query: 120 LWLTPHATMVISELEKAVL--KPRYTPYLG 147
           +           +L+  +      +TPYLG
Sbjct: 111 VEGPIE-----EKLKPFLEQGNFVFTPYLG 135


>UniRef50_A8UUT1 Putative uncharacterized protein n=1 Tax=Hydrogenivirga sp.
           128-5-R1-1 RepID=A8UUT1_9AQUI
          Length = 253

 Score = 73.9 bits (180), Expect = 4e-12,   Method: Composition-based stats.
 Identities = 26/196 (13%), Positives = 56/196 (28%), Gaps = 15/196 (7%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L   L G    + +     +  +  FP    + G++GA +G  +++       ++ +
Sbjct: 1   MKVLSFSLFGDFAHFRKFYTTSSPLSFPFPPPPTIRGIIGAIMGFSKEEY---LDKTKGI 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWR-----EYLCDASF 116
              V     +   R           +           +  +  +T R     E++ D  +
Sbjct: 58  SVGVSLKAPLKKVRMGLNLIFTKG-SSGKFDPTLVPWRKGDVNKTLRTQIKAEFIKDPIY 116

Query: 117 TVALWLTPHATMVISELEKAVL--KPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNY 174
            + L         I EL + +   +  YT  LG            G  + +    +    
Sbjct: 117 RIYLSA---DEDFIEELAELLKEHRSYYTVSLGLSELIADFSF-EGIYEGNKINISARVD 172

Query: 175 EPVGGDIYSEESVTGH 190
             V      E  +   
Sbjct: 173 SVVSTKFVQEIDLERP 188


>UniRef50_A4XGC7 CRISPR-associated protein Cas5 family n=1 Tax=Caldicellulosiruptor
           saccharolyticus DSM 8903 RepID=A4XGC7_CALS8
          Length = 275

 Score = 71.6 bits (174), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 24/165 (14%), Positives = 53/165 (32%), Gaps = 21/165 (12%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQ----------RDDTSSL 54
           L +++  P   +  P     R T   P  S +LGL+   LGI+          +D+ + L
Sbjct: 11  LKIKIYQPQAHFRIPFSYQRRHTYPIPPYSTVLGLIANILGIKNLPGQEEPCVKDNCNCL 70

Query: 55  QALSESVQFAV------RCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWR 108
               + ++  V      + +E        + + +  + ++               +    
Sbjct: 71  YHKLKQIKIGVCGNFETKVEEYFWLRNLKAESHIGRFGSITNRYVGGHIEHIGGQMPCIV 130

Query: 109 EYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPY---LGRRS 150
           + L +A   + L         +  ++ +   P        LGR  
Sbjct: 131 DVLHNARILIYL--YHCDKEFLEVIKSSFENPVNKTSVMHLGRAE 173


>UniRef50_UPI00016C61FD CRISPR-associated protein Cas5, hmari subtype n=1 Tax=Clostridium
           difficile QCD-76w55 RepID=UPI00016C61FD
          Length = 250

 Score = 70.5 bits (171), Expect = 4e-11,   Method: Composition-based stats.
 Identities = 33/220 (15%), Positives = 71/220 (32%), Gaps = 22/220 (10%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTR--PTGRFPTRSGLLGLLGACLGIQRDDTSSLQALS 58
           M   L   L G   ++ +PT+  +    T     +  LLG+LGA +GI        + L 
Sbjct: 1   MDEVLKFNLKGKGASFSKPTYNSSSIIQTYPHIHKVALLGILGAIIGIDNTGYKRKKELP 60

Query: 59  ESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV 118
           +  +  ++  ++ +  ++++     D  T      +        T     E L + S+ +
Sbjct: 61  KFYKL-LKDLKIAIAPKKLNFNKCVDVVTDTSGFSNKISPNVGSTYLINYEILINPSWDI 119

Query: 119 ALWLTPHATMVISELEKAV--LKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEP 176
            +          ++++K +      + P+LGR        LF    +             
Sbjct: 120 YIL---GDGEYYNKIKKYILNRSAVFHPFLGRNH------LFADLSEVEILNGEFSKELS 170

Query: 177 VGGDIY--------SEESVTGHHLKFTARDEPMITLPRQF 208
                +         +E +    L       P+    R+ 
Sbjct: 171 KIDSFFISDNVVLDEDEILLNEKLYLFKDSMPISIDNRKI 210


>UniRef50_B9D004 Crispr-associated protein Cas5 n=1 Tax=Campylobacter rectus RM3267
           RepID=B9D004_WOLRE
          Length = 246

 Score = 69.7 bits (169), Expect = 7e-11,   Method: Composition-based stats.
 Identities = 24/164 (14%), Positives = 47/164 (28%), Gaps = 18/164 (10%)

Query: 6   ILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRD-DTSSLQALSESVQFA 64
             ++ G    +  P       T   P ++ + G+L A LGI    +         SV   
Sbjct: 3   AFKIWGKFACFRDPLGISQNITLPIPPKTTICGMLAALLGIDNYLNDDRFDDFKYSVILD 62

Query: 65  VRCDELILDDRRVS----------VTGLR-DYHTVLGAREDYRGLKSHETIQTWREYLCD 113
               +       ++           + L+ D   +     D +           RE L  
Sbjct: 63  APILKKSFSQNYINDYTKFTKSHLNSLLKFDMQKISLGLRDNKA----PQKPINRELLIY 118

Query: 114 ASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPL 157
             + + +         I  L+K +   +++ YLG          
Sbjct: 119 PKYIIFIDKFKLEEEAIYNLKKRI--CKFSFYLGNSEFAGNFEF 160


>UniRef50_B8DZH7 CRISPR-associated protein Cas5, Hmari subtype n=6 Tax=Bacteria
           RepID=B8DZH7_DICTD
          Length = 238

 Score = 68.9 bits (167), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 22/148 (14%), Positives = 50/148 (33%), Gaps = 9/148 (6%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L+  + G +  + +     +  +  FP    +LG++GA  GI R     +    E+ 
Sbjct: 1   MKVLVFDIFGDLAHFRRFYTTSSPLSFSFPPPPTILGMIGAIAGIDRKKYLEVL-CPENC 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           + +++    I   R          +T     +  +    +   Q   E++ D  + V   
Sbjct: 60  KISLQIMNPIKKIRLGLNLI----NTKDNFWQPVKTKNHNARTQVKTEFIKDPRYRVY-- 113

Query: 122 LTPHATMVISELEKAVLK--PRYTPYLG 147
                  +  ++   +      +T  LG
Sbjct: 114 FYHKDENIFEDVINKIKNHETFFTFSLG 141


>UniRef50_B9LWL0 CRISPR-associated protein Cas5, Hmari subtype n=1 Tax=Halorubrum
           lacusprofundi ATCC 49239 RepID=B9LWL0_HALLT
          Length = 265

 Score = 68.9 bits (167), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 28/159 (17%), Positives = 49/159 (30%), Gaps = 12/159 (7%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
           + L L +      + +     T+ T R P R+ + G+L A +G  RD    +     S  
Sbjct: 13  TCLSLTVRSTWGHFKRVGRSVTKQTYRIPPRTTVAGMLAAIVGSDRDSYYDVFGADTS-A 71

Query: 63  FAVRCDELILDDRRVSVTGLRD-YHTVLGAREDYRG------LKSHETIQTWREYLCDAS 115
            A+     I      +     D    V       R           +      E L D  
Sbjct: 72  IAITPLFDIRTVNVPTTGLGTDPKQAVTKTAGSRRSYALTYQDTEGDRQIHAYELLTDPV 131

Query: 116 FTVALWLTPHATMVISELEKAVLK--PRYTPYLGRRSCP 152
           + + + +         +LE+ +      Y P LG+    
Sbjct: 132 YRIDVAV--EDEAYYEKLERRLDNEESYYPPSLGKSEYL 168


>UniRef50_C9RW51 CRISPR-associated protein Cas5, Hmari subtype n=2 Tax=Geobacillus
           RepID=C9RW51_GEOSY
          Length = 247

 Score = 68.5 bits (166), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 27/155 (17%), Positives = 51/155 (32%), Gaps = 10/155 (6%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQAL-SES 60
            + L+  +      + Q     +  T  F   +   GLLGA  G+ +++   L+    ++
Sbjct: 1   MNVLVFDIRADFGHFRQLYSTSSPLTHSFIPPTAFFGLLGAITGVGKEENEYLRVFNHKT 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
              A+R    +   R          +  +  +            Q   E+L    F   +
Sbjct: 61  TNMAIRLMGPVRKTRVGINYVNTKGNIWVPKQRRE-----GARTQIRVEFLRFPHFRCYV 115

Query: 121 WLTPHAT--MVISELEKAVLKPRYTPYLGRRSCPL 153
            +  H     +I  + +   K  YTP LG   C  
Sbjct: 116 SMNDHERFSYLIDLVRQ--HKSVYTPCLGLSECLA 148


>UniRef50_B0ABR7 Putative uncharacterized protein n=1 Tax=Clostridium bartlettii DSM
           16795 RepID=B0ABR7_9CLOT
          Length = 229

 Score = 68.5 bits (166), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 24/154 (15%), Positives = 53/154 (34%), Gaps = 20/154 (12%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L+ ++ G    + +     +  T        + GL+GA LGI R     L   ++ +
Sbjct: 6   MKCLVFKVRGDYARFRKSYTTTSALTYLLIHPVAVRGLIGAMLGIDR---EKLYEKTKDI 62

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           + A++    +  D +        ++ V     D              E+L +  + + + 
Sbjct: 63  EVAIQVVNQVRKDMQS-------FNLVNMKANDKIFRFPSNV-----EFLRNVEYRIFIK 110

Query: 122 LTPHATMVISELEKAVLKP--RYTPYLGRRSCPL 153
                   + E++  + +    +TPYLG      
Sbjct: 111 A---EDKTLYEIDNCIKQGEYIFTPYLGSSEHIA 141


>UniRef50_A4FXZ5 CRISPR-associated protein Cas5 n=1 Tax=Methanococcus maripaludis C5
           RepID=A4FXZ5_METM5
          Length = 233

 Score = 68.1 bits (165), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 21/165 (12%), Positives = 46/165 (27%), Gaps = 18/165 (10%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
             L   L G    + +     +  T   P R+ L+G++ + L  +RD   +  +  ++  
Sbjct: 5   KILEFELYGKFAHFKKFYSNASSLTYSVPPRTVLMGIVASVLEEKRDSYYNWLS-KDNAG 63

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWL 122
           F ++           +    ++  T   + E    +              +  + V    
Sbjct: 64  FGIQILSESRKGMYNTNYIGKNG-TSPTSVEIVMPVNH------------NVRYMVY--F 108

Query: 123 TPHATMVISELEKAV--LKPRYTPYLGRRSCPLTHPLFLGTCQAS 165
                      +K +      Y  Y G+R              A 
Sbjct: 109 YSTDQEKYELFKKRLIDENWGYGLYFGQRQFRAFAKFHKEYVGAE 153


>UniRef50_B8FSG3 CRISPR-associated protein Cas5 n=4 Tax=Firmicutes
           RepID=B8FSG3_DESHD
          Length = 231

 Score = 67.8 bits (164), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 28/165 (16%), Positives = 51/165 (30%), Gaps = 24/165 (14%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L   + G +  + +P    T+ T  F T +   GL+GA LGI        +    + 
Sbjct: 1   MKGLAFDVLGTVGHFRRPDTTATQLTYPFITPTAAKGLVGAILGI--------EDFVTTD 52

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +  +     +    +      +D               S     T  E L +  + +   
Sbjct: 53  RVGIELLRPVRTVAQQMSMLGKDP-------------GSTFNRPTTIELLVNPGYRIYYT 99

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASD 166
              +   ++  L     +  YT YLG  +  LT P+         
Sbjct: 100 GEEYTEQLLDFLTG--ERAVYTTYLG-TAYALTKPILYKVYPEVS 141


>UniRef50_C1TQC8 CRISPR-associated protein Cas5, Hmari subtype n=1
           Tax=Dethiosulfovibrio peptidovorans DSM 11002
           RepID=C1TQC8_9BACT
          Length = 236

 Score = 67.4 bits (163), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 34/224 (15%), Positives = 68/224 (30%), Gaps = 35/224 (15%)

Query: 6   ILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSS------LQALSE 59
           +  +  PM  + +P    +  +  FP  + + GL+ A  GI      S       + LS 
Sbjct: 4   VFDVTSPMAMFRKPYTTTSSVSYAFPPPTAVAGLISAISGISNGSDKSGCGAQYWKDLSG 63

Query: 60  -SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV 118
            S+   +R     +               V    ++      H       +++    + +
Sbjct: 64  TSIAVGIRGKVSWMSQALN-------MWNVKNPGKNAHIQVKH-------QFVARPRYRI 109

Query: 119 ALWLTPHATMVISELEKAVLK--PRYTPYLGRRSCPLTHPLFLGTCQASDPQK---ALLN 173
            +            L+  + +    YTP LG  +  L    ++G   ++ P     AL  
Sbjct: 110 YVSGGIED-----RLDGYLKRGAFVYTPCLG-TAYALADLEYVGRFGSASPDGGPLALDT 163

Query: 174 YEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIK 217
             P    +  +   +G          P+     +   R   VI 
Sbjct: 164 IVPWTDGMTVDVLSSG---GAFKERVPLQFDVGRGLVRACSVIY 204


>UniRef50_Q2NFS3 Putative uncharacterized protein n=1 Tax=Methanosphaera stadtmanae
           DSM 3091 RepID=Q2NFS3_METST
          Length = 282

 Score = 66.6 bits (161), Expect = 6e-10,   Method: Composition-based stats.
 Identities = 19/158 (12%), Positives = 48/158 (30%), Gaps = 13/158 (8%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRP-TGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             +   +      + +P        +   P ++ ++G++ + LGI+ DD           
Sbjct: 4   KLIEFNIESSFGCFNKPFSNKGGLLSYNIPPKTSIIGMVCSILGIEFDDYIEKDD----- 58

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
              VR   +           +     V  +R  +      +     ++ L    + + + 
Sbjct: 59  ---VRVYAIEKFYDIKVSVQM--MSKVRSSRIIFNNTSDGDIANIHQDLLIKPKYKIFIS 113

Query: 122 LTPHATMVISELEKAVLK--PRYTPYLGRRSCPLTHPL 157
                     +    + K    Y  Y+GR   P+++  
Sbjct: 114 FPDTLVEYEKDFINKLKKHETVYNLYMGRNEFPISYEF 151


>UniRef50_A7VC52 Putative uncharacterized protein n=1 Tax=Clostridium sp. L2-50
           RepID=A7VC52_9CLOT
          Length = 238

 Score = 64.7 bits (156), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 21/148 (14%), Positives = 45/148 (30%), Gaps = 7/148 (4%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M   + +     +  + +P+    + +   P  S ++G++ A  G   D    +Q   + 
Sbjct: 4   MERAIRIDCFQNLANYRKPSSFIIKESYPLPPYSTVIGMIHAISGF--DSYHKMQVSIQG 61

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
                  +       +         H +    ED              E +CD    + +
Sbjct: 62  ENAGSVSELYTRYSFKFDTKYEEGRHQLCIKGEDKDYGVFKG--IAHVELICDNRMVLHI 119

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGR 148
                      ++ +A+  P   P LGR
Sbjct: 120 I---PEEEDFDKIYQALKCPIIYPSLGR 144


>UniRef50_Q0AW00 CRISPR-associated protein, Cas5h family n=2 Tax=Clostridiales
           RepID=Q0AW00_SYNWW
          Length = 246

 Score = 64.7 bits (156), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 34/158 (21%), Positives = 56/158 (35%), Gaps = 6/158 (3%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRP-TGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
              L   L+GP+  + QP        T     +  LLGLLGA +G+     + L    E 
Sbjct: 1   MKSLRFTLSGPLACFRQPDVNAKVYFTYNNIHKVALLGLLGAVIGLSGYRNADLYGQGEK 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRG---LKSHETIQTWREYLCDASFT 117
           +          L    V       +   +    +  G    +    +Q   ++L + ++T
Sbjct: 61  LYPEFYEVLSPLLVSVVPNVKNGYFSKKIQYFNNSVGYASKEEGGNLQVREQWLENPNWT 120

Query: 118 VALWLTPHATMVISELEKAVLK--PRYTPYLGRRSCPL 153
           V L        +  +L   +L+    Y PYLGR   P 
Sbjct: 121 VFLAQHKLDASIWDKLCDYMLRGQCVYIPYLGRNDFPA 158


>UniRef50_C9M4F0 Putative uncharacterized protein n=1 Tax=Lactobacillus helveticus
           DSM 20075 RepID=C9M4F0_LACHE
          Length = 237

 Score = 63.9 bits (154), Expect = 4e-09,   Method: Composition-based stats.
 Identities = 24/149 (16%), Positives = 43/149 (28%), Gaps = 10/149 (6%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              + ++L      +  P   G R +   P  S ++G++         D      +  SV
Sbjct: 1   MKVIRVKLHQETANYRVPASHGFRESYPLPPISTVIGMVHYLC-----DFHEYHPMKVSV 55

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           Q             R        +              S        + L D +  + + 
Sbjct: 56  Q-GSYVSTTSDFFTRYEFKNGLKFDPGRHQLNAEGYGISRG--IGHVQLLYDVNLILHI- 111

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRS 150
             P     + ++  A+  PR  P LGRR 
Sbjct: 112 -KPDDENELEDIYNALKYPREFPNLGRRE 139


>UniRef50_B1L2N4 Crispr-associated protein Cas5, hmari subtype n=3 Tax=Clostridium
           botulinum RepID=B1L2N4_CLOBM
          Length = 253

 Score = 63.9 bits (154), Expect = 4e-09,   Method: Composition-based stats.
 Identities = 24/153 (15%), Positives = 59/153 (38%), Gaps = 7/153 (4%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRP-TGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
              +   L+GP   + +P        T     +  LLG+LG+ +G++  +          
Sbjct: 1   MEAIKFNLSGPTAFFKKPDVNSYAYFTYNNIHKIALLGILGSIIGLKGYNQQKSIDTYPE 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSH-ETIQTWRE-YLCDASFTV 118
               ++  ++ +  +  +    + + T       Y    +       +RE +L + S+ +
Sbjct: 61  FYDKLKTLKISIVPKSKTGYFTKKFQTFTNNTGFYNIDINKRPCTLVYREQWLENVSWDI 120

Query: 119 ALWLTPH--ATMVISELEKAV--LKPRYTPYLG 147
            + L  +     ++++L+  +   K  + PYLG
Sbjct: 121 YILLDENSVDKKILNKLKDYLLNKKCHFIPYLG 153


>UniRef50_A4XM40 CRISPR-associated protein Cas5 family n=3 Tax=Clostridia
           RepID=A4XM40_CALS8
          Length = 249

 Score = 63.9 bits (154), Expect = 4e-09,   Method: Composition-based stats.
 Identities = 20/156 (12%), Positives = 45/156 (28%), Gaps = 27/156 (17%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSL-------- 54
             L ++L  P   + +P   G   +   P  S + G L   LG +  +   +        
Sbjct: 4   KLLKIKLYQPFANFRKPFSYGIVDSYPLPPPSTVKGWLHNILGAKNGEYYKMAVSICGKF 63

Query: 55  QALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDA 114
            ++   +Q  ++ D L  +D    +                           +   L D 
Sbjct: 64  NSIVYDIQRIIKFDRLRKEDSSAPI--------------LKDVSARVINDVIYVTNLVDV 109

Query: 115 SFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRS 150
              + +        ++  +   +    +   LGR+ 
Sbjct: 110 ELCIHVNA---EQEILERISHNIFNSYWG--LGRKE 140


>UniRef50_B7AS04 Putative uncharacterized protein n=1 Tax=Bacteroides pectinophilus
           ATCC 43243 RepID=B7AS04_9BACE
          Length = 241

 Score = 63.5 bits (153), Expect = 5e-09,   Method: Composition-based stats.
 Identities = 21/150 (14%), Positives = 48/150 (32%), Gaps = 11/150 (7%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M   + L+    +  + +P+    + T   P  S + G++ A  G +      L  +  S
Sbjct: 1   MVKAIRLQCYQNLANYRKPSSFIIKETYPLPPYSTVSGMIHAACGFK-----ELHRMKLS 55

Query: 61  VQFAVR--CDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV 118
           +Q   R    E+       +     +    +  ++               E +C+ +  +
Sbjct: 56  IQGTNRGTISEVYTRYSFSAGAKYEEGRHQICLKDGENYGIYKG--VANAELVCENNMII 113

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGR 148
            +   P     +  +   +  P     LGR
Sbjct: 114 HI--LPEREEDMDVIYNGLSNPLMYLSLGR 141


>UniRef50_C9XLN6 Putative uncharacterized protein n=6 Tax=Clostridium difficile
           RepID=C9XLN6_CLODC
          Length = 268

 Score = 63.1 bits (152), Expect = 7e-09,   Method: Composition-based stats.
 Identities = 20/166 (12%), Positives = 47/166 (28%), Gaps = 29/166 (17%)

Query: 2   RSYLILRLAGPMQAWGQPTFE--GTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE 59
              L  +L  P   +  P         T   P+++ ++G++              + L+ 
Sbjct: 1   MKVLQCKLKQPTAHYRDPKVFQNEYISTLNLPSKTTIMGMI---------TYLCDRRLNS 51

Query: 60  SVQFAVR---------------CDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETI 104
            +   +                 D                +       + Y+  K+  +I
Sbjct: 52  DIDIGIIGTHHHRELEFSRGENIDFWNEYTNMRKGKDKEKFLLQGNYYDYYKEHKAQNSI 111

Query: 105 QTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRS 150
             + E L +   T+ +         +  ++K +  P     LGR+ 
Sbjct: 112 LNY-EVLKEVELTIFISCKDDEE--LEFIKKKLESPCKYANLGRKE 154


>UniRef50_Q12WX6 CRISPR-associated protein Cas5, Hmari subtype n=1
           Tax=Methanococcoides burtonii DSM 6242
           RepID=Q12WX6_METBU
          Length = 264

 Score = 62.7 bits (151), Expect = 8e-09,   Method: Composition-based stats.
 Identities = 25/150 (16%), Positives = 52/150 (34%), Gaps = 4/150 (2%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
             L  RL G    + QP     R T     +  LLGL+G+ +G+     +++     S  
Sbjct: 31  KLLTFRLYGSFAHFNQPISNRFRNTYSIIPKPQLLGLIGSIVGLSGYKNAAVSPEFYSKL 90

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWL 122
             ++             T    Y+++     +     S   I   +  L D  + V + +
Sbjct: 91  SDLKVFIKCNSLSEKKFTLS--YNSLNSFLNNRIDSGSPNVIIKEQVLL-DPDYEVGIVV 147

Query: 123 TPHATMVISELEK-AVLKPRYTPYLGRRSC 151
             +  + +  ++K  +    +  Y G+   
Sbjct: 148 NENNPLHLEIIDKIRMNCGVFPIYFGKNEF 177


>UniRef50_A1ZVP9 Crispr-associated protein Cas5, tneap subtype n=1 Tax=Microscilla
           marina ATCC 23134 RepID=A1ZVP9_9SPHI
          Length = 218

 Score = 62.7 bits (151), Expect = 8e-09,   Method: Composition-based stats.
 Identities = 25/149 (16%), Positives = 43/149 (28%), Gaps = 27/149 (18%)

Query: 2   RSYLILRLAGPMQAWGQP-TFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
                + +     ++  P    G +PT   P  S +LGL+ A  G       +   L   
Sbjct: 1   MRVFKIDITSWTASFRYPNLISGFQPTLEVPPVSTVLGLINAAAGH----YVAHSTLKLG 56

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTV-LGAREDYRGLKSHETIQTWREYLCDASFTVA 119
             F  +             +   D  T+              ++    RE+L +A   + 
Sbjct: 57  YYFEYQ-------------SKAVDLETIYQIGAHKGMPSNHAKSNIIRREFLFEAFLRLY 103

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGR 148
           +           E+      P Y   LGR
Sbjct: 104 VTS--------QEVADYFRSPVYPIVLGR 124


>UniRef50_C9L3W3 CRISPR-associated protein Cas5, Tneap subtype n=2 Tax=Clostridiales
           RepID=C9L3W3_RUMHA
          Length = 241

 Score = 62.4 bits (150), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 21/148 (14%), Positives = 45/148 (30%), Gaps = 8/148 (5%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M   + L+    +  + +P+    + T   P  S +LG++ A              LS  
Sbjct: 1   MEKAIRLQCFQNLANYRKPSSFIIKETFPLPPYSTVLGMIHAACEFT---EFHPMKLSIQ 57

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
              A    EL       S +   +    +  ++               E +C+    + +
Sbjct: 58  GTNAGTISELYTRYSFSSGSKYEEGRHQICIKDKENYGIFKG--IANVELVCNNRMVIHI 115

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGR 148
                      ++ +++  P     LGR
Sbjct: 116 VPGEED---FQKVYESLKNPPKYLSLGR 140


>UniRef50_A6TQ83 CRISPR-associated protein Cas5 family n=9 Tax=Bacteria
           RepID=A6TQ83_ALKMQ
          Length = 259

 Score = 62.4 bits (150), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 34/212 (16%), Positives = 72/212 (33%), Gaps = 19/212 (8%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
           +  + ++L      + +PT    + T   P  S ++G++ +    +  +   +    +  
Sbjct: 5   KKAVRIKLYQETANYKKPTSFQLKETYPLPPYSTVIGMVHSLCDYK--EYKEMNISIQGK 62

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
            F+   D     + +  +T     H +        G           E L +    + + 
Sbjct: 63  YFSKTNDLFTRYEFKNGMTFDSTRHQIQV------GDFGVGQGVATTELLVEVELLIHI- 115

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
             P    +I E+E+A L PR  P LGRR         L            ++ + +  D+
Sbjct: 116 -IPTDQDLIQEIEQAFLYPREYPSLGRRE-------DLAVINEVTVVD--ISEKELEEDV 165

Query: 182 YSEESVTGHHLKFTARDEPMITLPRQFASREW 213
             +E+   +      RDE ++    +   R  
Sbjct: 166 VLDENYAAYIPLKMIRDEEVVLDGAEPGIRSR 197


>UniRef50_A1HND7 CRISPR-associated protein Cas5 family n=1 Tax=Thermosinus
           carboxydivorans Nor1 RepID=A1HND7_9FIRM
          Length = 257

 Score = 62.0 bits (149), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 37/231 (16%), Positives = 64/231 (27%), Gaps = 29/231 (12%)

Query: 3   SYLILRLAGPMQAWGQPTFE-GTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             L + ++    ++  P    G  PT   P  + + G L    G    +  +   L  S 
Sbjct: 6   DVLKIEMSAMTASFRYPHVMIGRLPTFEMPPPATIYGHLCGVWG----EWFNPGDLEFSY 61

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTV---LGAREDYRGLKSHETIQT----WREYLCDA 114
            F                  +   H +    G  E   G        +     R++L   
Sbjct: 62  VFT----------HGGIGEDVELGHMIEFGSGRSEKTLGGLPKNMKGSLNPQRRQFLFRP 111

Query: 115 SFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLT--HPLFLGTCQASDPQKALL 172
             T+ L        ++  LE+A   P +   LGR     T     +    QAS    A  
Sbjct: 112 RMTLYL---KGDDKILQRLEQAFKSPAFAYILGRSQDLATVHSITWARLKQASGAFFANT 168

Query: 173 NYEPVGGDIYS--EESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMD 221
                     S          + +    EP+     +   R   +   G++
Sbjct: 169 LLPWTLRQWVSVGRPVYMPKWINYHKLREPVFERYLEIDDRPLRIFGEGVE 219


>UniRef50_A5ILM6 CRISPR-associated protein Cas5 family n=3 Tax=Thermotogaceae
           RepID=A5ILM6_THEP1
          Length = 260

 Score = 60.8 bits (146), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 23/158 (14%), Positives = 54/158 (34%), Gaps = 16/158 (10%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQA-LSES 60
              L + +      +  P F   R T   P  S  +GL+   L     D S +++ L+  
Sbjct: 1   MKLLRIEVKASTAHFAIPFFIFERKTFPIPMYSTAIGLICNIL----SDESKIESFLNSE 56

Query: 61  VQFAV------RCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDA 114
              A+        +E          + ++ + ++     ++        + T  + L + 
Sbjct: 57  FSMAIVGNHEGVVEEYTWLRNLEKGSHVKKFKSLRNREINHEIEHPGGQMPTRIQTLVNP 116

Query: 115 SFTVALWLTPHATMVISELEKAVLKPRYT--PYLGRRS 150
              + +        V+  +++++  P Y    +LGR  
Sbjct: 117 RVDLFVKA---KEDVLEMIKQSLENPGYISRIHLGRSE 151


>UniRef50_B8DAB1 Crispr-associated protein Cas5, tneap subtype n=3 Tax=Firmicutes
           RepID=B8DAB1_LISMH
          Length = 207

 Score = 59.7 bits (143), Expect = 7e-08,   Method: Composition-based stats.
 Identities = 23/149 (15%), Positives = 49/149 (32%), Gaps = 10/149 (6%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              + ++L   +  + +PT    + T   P  S ++G++    G          ++    
Sbjct: 1   MKAIRVKLWQDLVNFKKPTSFQLKETYPLPPYSTVIGMVHTLCGFT-SYHEMKISIQGKY 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
              V       + +         +   +      RG        +  E + D    + + 
Sbjct: 60  FSKVNDLATRYEFKNGMTYDASRHQIKVDKYGVSRG-------VSTVELIVDLELLLHI- 111

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRS 150
             P  + ++  +EKA  +P   P LGRR 
Sbjct: 112 -IPEDSSLVPIIEKAFSEPIEFPSLGRRE 139


>UniRef50_B5YL08 CRISPR-associated protein Cas5 n=1 Tax=Thermodesulfovibrio
           yellowstonii DSM 11347 RepID=B5YL08_THEYD
          Length = 257

 Score = 58.5 bits (140), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 23/156 (14%), Positives = 55/156 (35%), Gaps = 15/156 (9%)

Query: 2   RSYLILRLA-GPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
              L+  +    + +   P    +  T   P  S ++G+L   L   ++D   LQ L + 
Sbjct: 1   MKALVFHIRLNSLYSIRIPFTWQSALTYPVPPPSAVIGMLANALQRYKNDRHPLQYLEK- 59

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFT--V 118
               +  + +    + +S   ++ Y T     +    +    T    R++    ++   +
Sbjct: 60  ----IENELIWAGSKLLSPCIIKSY-TTSAIVKWDDTMPWKFTNAIGRQF----AYAQQI 110

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLT 154
            +        +++E+ KA+         G    P+T
Sbjct: 111 QIATIFKDESIVNEIVKALK--ISPLTCGDSESPIT 144


>UniRef50_A9WFZ3 CRISPR-associated protein Cas5 family n=6 Tax=Chloroflexi (class)
           RepID=A9WFZ3_CHLAA
          Length = 252

 Score = 57.7 bits (138), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 28/153 (18%), Positives = 44/153 (28%), Gaps = 27/153 (17%)

Query: 2   RSYLILRLAGPMQAWGQPTFE-GTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
              L + L     ++  P F  G +P+   P  + + G + + LG    D      L+ +
Sbjct: 8   MQALKIVLEALTTSFRYPHFMLGVQPSFPLPPPATIYGHICSALG----DWVDPAGLAFA 63

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSH----ETIQTWREYLCDASF 116
             F                  L   H +  +     G +            R+ L     
Sbjct: 64  YHFT----------AAGEGHDLEHIHVLSASSGKLPGGEPKVLEGNINPFKRQLLLFPRL 113

Query: 117 TVALWLTPHATMVISELEKAVLKPRYTPYLGRR 149
           T+ L           E   A   PRY   LGR 
Sbjct: 114 TLYLNRP--------EWIDAFRFPRYPVVLGRS 138


>UniRef50_C5VUI7 Crispr-associated protein Cas5, hmari subtype n=1 Tax=Clostridium
           phage D-1873 RepID=C5VUI7_9VIRU
          Length = 237

 Score = 57.0 bits (136), Expect = 5e-07,   Method: Composition-based stats.
 Identities = 24/215 (11%), Positives = 61/215 (28%), Gaps = 23/215 (10%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGT-RPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
                  ++G    + +P        +     +  +LGLLGA +G+ +D   +       
Sbjct: 1   MRGFKFNVSGKTAFFKKPDINQYINFSYSHIHKPCILGLLGAIIGLDKDSYYNTLK---H 57

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWRE-YLCDASFTVA 119
           ++ ++                 +         +      ++ T    RE +L + S+ + 
Sbjct: 58  LKISI---------VPNKPYFNKSIQVYNNTTKFANKSLNNPTTLNVREQWLENVSWDIY 108

Query: 120 LWLTPHATMVISELEKAVL--KPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPV 177
           +       ++  ++ + +   K  Y  Y GR+    +            P+         
Sbjct: 109 IIAEDKD-VIYDKIYEYIRGFKSVYNIYFGRKEHITSIMFIEDFDIQDVPEDVFQINGLF 167

Query: 178 GGDIY------SEESVTGHHLKFTARDEPMITLPR 206
             +I         +        F     P+    +
Sbjct: 168 PYNIINEIGTNKSDESKDKVSYFLKETMPIRYNNK 202


>UniRef50_B3EG03 CRISPR-associated protein Cas5 family n=4 Tax=cellular organisms
           RepID=B3EG03_CHLL2
          Length = 206

 Score = 56.6 bits (135), Expect = 6e-07,   Method: Composition-based stats.
 Identities = 24/150 (16%), Positives = 41/150 (27%), Gaps = 31/150 (20%)

Query: 2   RSYLILRLAGPMQAWGQP-TFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
              L +++     ++  P    G +PT   P  S + GL+ A  G               
Sbjct: 1   MKLLRIKIRSWTASFRYPIFVAGFQPTLPMPPLSTIYGLISAAKG--------------- 45

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
                  +  +            D  T+                   RE+L D    + L
Sbjct: 46  -NIVTPEETSVGYVFSYQ-AKAVDLETIYEIEGLKAKSN-----VANREFLFDNELYLYL 98

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRS 150
                      +LE    +P +   LGR +
Sbjct: 99  TNL--------DLESVFRRPHHPILLGRST 120


>UniRef50_O66696 Putative uncharacterized protein n=2 Tax=Aquificaceae
           RepID=O66696_AQUAE
          Length = 219

 Score = 56.2 bits (134), Expect = 9e-07,   Method: Composition-based stats.
 Identities = 40/228 (17%), Positives = 71/228 (31%), Gaps = 28/228 (12%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L      P+  +  P       T   P  S ++GLL    G +              
Sbjct: 1   MECLKAEFFSPIALFKTPFSIKGIETYPLPPYSTVIGLLYTASGKKW------------- 47

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
               + +   +  +       RDY   +  R+  +  K  ET+        +   TV + 
Sbjct: 48  ----KGERFNISVQGDYEAIFRDY---VRFRKYNKKDKKLETLPLEVPLFYNFRLTVHIL 100

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTH-PLFLGTCQASDPQKA-LLNYEPVGG 179
                  ++ E EKA+  P   PYL     P+    + +  C+        +     +  
Sbjct: 101 ---GDENLLKEFEKALKFPYVFPYLSGGEYPVKITKVKMVACRKEYFDTFNIPKNAYIPE 157

Query: 180 DIYSEESVTGHHLKFTARDEP---MITLPRQFASREWYVIKGGMDVSQ 224
           +I++EE              P   +   PRQ      Y ++ G  VS+
Sbjct: 158 NIFTEEFRVSLEGHGVYYRVPSFLISQKPRQHEWVGVYYVQKGTKVSE 205


>UniRef50_D1QSA9 CRISPR-associated protein Cas5, Tneap subtype n=1 Tax=Prevotella
           oris F0302 RepID=D1QSA9_9BACT
          Length = 224

 Score = 55.8 bits (133), Expect = 9e-07,   Method: Composition-based stats.
 Identities = 26/151 (17%), Positives = 50/151 (33%), Gaps = 27/151 (17%)

Query: 2   RSYLILRLAGPMQAWGQP-TFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
                ++++    ++  P    G +PT   P  S +LGL+ AC G       +   +   
Sbjct: 1   MKVFRIKISAWTASFRYPNIISGYQPTLEVPPLSTILGLMNACAGR----YLNHADMEIG 56

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSH-ETIQTWREYLCDASFTVA 119
             F  R             +   D  T+   + D    K   ++    R++L D +  + 
Sbjct: 57  YYFNYR-------------SISNDLETIYQMKYDKGTAKKQVKSNVINRQFLFDNTLYIY 103

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRS 150
           +        +  +  K    P +   LGR  
Sbjct: 104 I--------IDKDFVKYFQTPAFQILLGRSC 126


>UniRef50_Q0ATZ7 CRISPR-associated protein, Cas5h family n=1 Tax=Syntrophomonas
           wolfei subsp. wolfei str. Goettingen RepID=Q0ATZ7_SYNWW
          Length = 231

 Score = 55.8 bits (133), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 25/164 (15%), Positives = 55/164 (33%), Gaps = 24/164 (14%)

Query: 13  MQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSS------LQALSESVQFAVR 66
           M  + +P    +  +  FP  + + GL+   +GI  + +         + + E VQ A+ 
Sbjct: 1   MALFRKPYTTTSMVSYPFPPPTAIAGLIAGIIGINHEASQDAKNARYWEKMRE-VQVAIA 59

Query: 67  CDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPHA 126
               I                V   +         E IQ   + +    + + +      
Sbjct: 60  LLSPIRWINTA----------VNLMKYKNSNADMSEHIQVKHQLVKKPRYRIYVQGG--- 106

Query: 127 TMVISELEKAVLK--PRYTPYLGRRSCPLTHPLFLGTCQASDPQ 168
             +   L++ + +    YTP LG  +  L    + G  + ++ +
Sbjct: 107 -EIYKILKQRLEREEFIYTPCLG-AAYALADIKYHGEYEPAEAE 148


>UniRef50_C9XPZ9 Putative uncharacterized protein n=5 Tax=Clostridium difficile
           RepID=C9XPZ9_CLODC
          Length = 233

 Score = 55.4 bits (132), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 21/149 (14%), Positives = 44/149 (29%), Gaps = 26/149 (17%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L L L      + +P       T   P  S + GL+   L             +E +
Sbjct: 1   MKVLKLDLFQETACYKKPFAMKITETYPLPPYSTINGLIHKIL-----------NATEYI 49

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
            F +         +    +   +Y T    ++D        +       L + +  + + 
Sbjct: 50  PFNISV-------QGTYESIFNNYQTTYFYKKDSITSMPMNSHM-----LLNVNLIIHI- 96

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRS 150
                  ++ E+  ++L       LGR+ 
Sbjct: 97  --GGDFDLLEEIYDSLLNYDEHLSLGRKE 123


>UniRef50_B1BR50 Crispr-associated protein Cas5 n=1 Tax=Clostridium perfringens E
           str. JGS1987 RepID=B1BR50_CLOPE
          Length = 233

 Score = 55.4 bits (132), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 24/158 (15%), Positives = 41/158 (25%), Gaps = 18/158 (11%)

Query: 2   RSYLILRLAGPMQAWGQPTFE--GTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE 59
              +   ++G    +  P +       +     +  LLG+LGA LG             E
Sbjct: 1   MKCIKFNISGKYAFFKNPEYNLNSYEYSFEHIHKPALLGILGAILGFDGKLQFKKNNKLE 60

Query: 60  SV----QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDAS 115
                    V  +                 H                +    R  L +  
Sbjct: 61  YYEELKNIKVAIEPYSSIFE----------HFEYDFVNGTGYANKGNSQMIKRMCLYNPL 110

Query: 116 FTVALWLTPHATMVISELEKAV--LKPRYTPYLGRRSC 151
           +T+ +        +   L K +   K +Y  YLG  S 
Sbjct: 111 WTIYILGESIDEKMYINLNKHLSSHKSKYPIYLGDNSF 148


>UniRef50_Q2RHQ8 Putative uncharacterized protein n=1 Tax=Moorella thermoacetica
           ATCC 39073 RepID=Q2RHQ8_MOOTA
          Length = 294

 Score = 55.4 bits (132), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 27/157 (17%), Positives = 42/157 (26%), Gaps = 14/157 (8%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
             L L        +   +    R T   P  S ++GLL   LG  R    ++  L+  + 
Sbjct: 10  RVLKLGFTAASAHFRVTSSNNPRKTYPLPPYSTVIGLLANILG-DRAKIEAM--LAGGLA 66

Query: 63  FAV------RCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASF 116
             V         E               +++    R                E L D   
Sbjct: 67  LGVLAQHNYITKEYTWLRNMSPSAHKGRFYSYDNRRWQETPEHPGGQSPVVVEVLNDVK- 125

Query: 117 TVALWLTPHATMVISELEKAVLKPRY---TPYLGRRS 150
            V ++L      V   L +    P       +LGR  
Sbjct: 126 -VYVYLYHPNEQVTGFLMENACLPERWLSHLHLGRAE 161


>UniRef50_B5YIV3 CRISPR-associated protein Cas5 n=1 Tax=Thermodesulfovibrio
           yellowstonii DSM 11347 RepID=B5YIV3_THEYD
          Length = 239

 Score = 54.7 bits (130), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 29/227 (12%), Positives = 71/227 (31%), Gaps = 21/227 (9%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              + ++L   M  + +    G   T   PT S + G+  + L + +     + ++  + 
Sbjct: 1   MKAVRIKLYQNMVNYRKELSYGYVQTYPLPTPSMVKGMAHSLLNLNKYHNLKI-SIQGNY 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
              V   + +    RV     R++      R    G +       + + + D    + + 
Sbjct: 60  ASVVTNMQKVYKFDRVRDDKKREF-IDPRPRIYAGGQRVLNQGIMFVDEIVDMELILHIS 118

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEP----- 176
                  +  +L +A+ +   T  LGR        +     + +     L   +      
Sbjct: 119 F--DDEGLNDKLLEALKQ--KTVILGR-----NEDIARVDFEDTSLVDILSFSDEYRLPY 169

Query: 177 ---VGGDIYSEESVTGHHLKFTARDEPM-ITLPRQFASREWYVIKGG 219
              +  ++  +E + G   +     EP+     ++   R    I   
Sbjct: 170 NIYLAPELCKKEQLEGTCYRLPFYYEPVNSFTDKRIF-RYVNAIYIA 215


>UniRef50_B7GIV5 CRISPR system related protein, RAMP superfamily n=3 Tax=Bacillaceae
           RepID=B7GIV5_ANOFW
          Length = 233

 Score = 54.7 bits (130), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 21/149 (14%), Positives = 42/149 (28%), Gaps = 8/149 (5%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L L+L      + +P       T   P  S + G++ A L     D      LS   
Sbjct: 1   MKALRLKLFQETACYKKPFASKVAETYPLPPYSTVKGMIHALL---NADQFIPMRLSVQG 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHE--TIQTWREYLCDASFTVA 119
            +  +  +                  + G          +E  T+  +   L +    + 
Sbjct: 58  TYEEKLLDYQRYYFFKKKELSSFPLVLDGLARMEFSYDKNEITTMPMYTHLLHNVHLLIH 117

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGR 148
           +        ++ ++  A+        LGR
Sbjct: 118 IEA---EQHILKQIIHAIEYSMTHYSLGR 143


>UniRef50_C1QDM0 CRISPR-associated protein Cas5 n=1 Tax=Brachyspira murdochii DSM
           12563 RepID=C1QDM0_9SPIR
          Length = 246

 Score = 54.7 bits (130), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 19/146 (13%), Positives = 48/146 (32%), Gaps = 5/146 (3%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
             + +     M  + +P+    + + + P  S ++G++      +  +   ++   +   
Sbjct: 7   KAIKIECYQNMPNYKRPSSIQFQESFKLPPYSTVIGMIHKVCSCKSGEYMPMKVSIQGET 66

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWL 122
            +   D        +     R    V      + G+        + E + D +  + +  
Sbjct: 67  KSSLTDLYTRYFFGIKYDPSRHQLKVKNPDGSFDGITKG---LGYAEVIVDVNLIIHIV- 122

Query: 123 TPHATMVISELEKAVLKPRYTPYLGR 148
            P    +   + K + KP   P LGR
Sbjct: 123 -PEDESLFDFILKGLKKPCVYPALGR 147


>UniRef50_C0QHV7 Putative CRISPR-associated protein Cas5 n=1 Tax=Desulfobacterium
           autotrophicum HRM2 RepID=C0QHV7_DESAH
          Length = 280

 Score = 54.3 bits (129), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 24/197 (12%), Positives = 44/197 (22%), Gaps = 59/197 (29%)

Query: 15  AWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDT---SSLQALSESVQFAVRCDELI 71
            +  P       T   P ++ + G+L A LGI  +D            S+       +  
Sbjct: 1   MFRDPLTITQNMTFPIPPKTTVGGMLAAILGIDYNDYLNDPEFFNFRYSLVLEKPVRKKS 60

Query: 72  LDDRRVS-------------------VTGLRDYHTVLGAREDYRGLKSHETIQ------- 105
                V+                       +D        E+   L   E          
Sbjct: 61  FVQNYVANYTKGSEKKFNAIKKYLESGKKQKDLLFEKEQLEEESDLTKKEEKLLGSIGGK 120

Query: 106 ----------------------------TWREYLCDASFTVALWLTPHATMVISELEKAV 137
                                        +RE L    + V +    +   ++  LE   
Sbjct: 121 IESESMTLEKASASCSKVFNESFTSPKPIFRELLVAPEYLVFIHDFKYEKEILHSLENHF 180

Query: 138 LKPRYTPYLGRRSCPLT 154
               ++ Y+G       
Sbjct: 181 --SEFSLYMGNSEFSAN 195


>UniRef50_C3HBA5 Putative uncharacterized protein n=2 Tax=Bacillus thuringiensis
           RepID=C3HBA5_BACTU
          Length = 255

 Score = 53.5 bits (127), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 24/173 (13%), Positives = 50/173 (28%), Gaps = 28/173 (16%)

Query: 2   RSYLILRLAGPMQAWGQPTFE-GTRPTGRFPTRSGLLGLLGACLGIQR------------ 48
              +   L G    + +P        T     +  L GLLGA +G               
Sbjct: 1   MKAIAFELKGRTAFFKKPDVNANIYFTYSHIHKIALYGLLGAIIGAGGYTQQQKSIIDEG 60

Query: 49  ----DDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETI 104
               +       L   ++ ++                 +           Y   ++   +
Sbjct: 61  NSTSNQYPEFYQLLNKLKVSI-------VPHGDRGYFSKKSQVFNNTV-GYASREAGGNL 112

Query: 105 QTWREYLCDASFTVALWLTPH-ATMVISELEKAVLKP--RYTPYLGRRSCPLT 154
               ++L +  +T+ LW        + + L+  ++    +Y PYLG+   P  
Sbjct: 113 IVQEQWLENPHWTIYLWNDGSLEEEIFNNLKNHLISSAYKYLPYLGKNDHPAN 165


>UniRef50_A7GQ89 CRISPR-associated protein Cas5 family n=1 Tax=Bacillus cytotoxicus
           NVH 391-98 RepID=A7GQ89_BACCN
          Length = 232

 Score = 52.7 bits (125), Expect = 8e-06,   Method: Composition-based stats.
 Identities = 18/148 (12%), Positives = 41/148 (27%), Gaps = 9/148 (6%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              + L+L      + +P       T   P  S + G++   L       + L  L  S+
Sbjct: 1   MKVIRLKLFQETACYTKPFANKVAETYPLPPYSTVKGMIHQLL-----QANELLPLRFSI 55

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQT-WREYLCDASFTVAL 120
           Q       +      +          +          + H T    +   L +    + +
Sbjct: 56  QGNYETKLIDYRKSYMVKKKSVSMPIIFDGLAMEVPEQEHMTSMPLYTHMLFNVELVIHI 115

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGR 148
                   ++  + +  ++      LGR
Sbjct: 116 A---GEEALLERIYQHFIELNQHLSLGR 140


>UniRef50_Q1Q0Z9 Putative uncharacterized protein n=1 Tax=Candidatus Kuenenia
           stuttgartiensis RepID=Q1Q0Z9_9BACT
          Length = 265

 Score = 52.3 bits (124), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 34/240 (14%), Positives = 73/240 (30%), Gaps = 28/240 (11%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRP-TGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
            +     LAG M  + +         +  F  +  +LG++GA LGI    + S       
Sbjct: 1   MNVFSFELAGDMAFFKKNDANDMVYISYNFLHKPAVLGIIGAILGIP-GYSESKAKQHPD 59

Query: 61  VQFAVRCDELILDDRRVSV--TGLRDYHTVLGAREDYRGLKSHETIQTWREYL--CDASF 116
               ++  ++ +           +  ++          G +        +  +   +  +
Sbjct: 60  FYTNLKDMKIAILPHYEKPLKKVITGFNNASCLASKSSGGQGQTWQIREQILIGEQEIRY 119

Query: 117 TVALWLTPH-ATMVISELEKAV--LKPRYTPYLGRRSCPL---------THPLFLGTCQA 164
           TV +         +IS+L+K +   +  Y  Y G+                PL       
Sbjct: 120 TVFVLDNNAIQDGLISKLKKLLINRESEYPLYFGKNEFFAYHENYQEYEAAPLSASEASV 179

Query: 165 SDPQKA-------LLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIK 217
               KA       L  +     D + ++   G+ +       P     R F  ++ +V+ 
Sbjct: 180 CGLVKAGDKNTNILREFSFEDFDPFEKKLNEGYTIYEHL---PYDFDARGFYKKDVFVLT 236


>UniRef50_A0RNQ4 Crispr-associated protein Cas5, hmari subtype n=2 Tax=Campylobacter
           RepID=A0RNQ4_CAMFF
          Length = 253

 Score = 52.0 bits (123), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 28/236 (11%), Positives = 65/236 (27%), Gaps = 43/236 (18%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRP-TGRFPTRSGLLGLLGACLGI-------------- 46
              +  +L+G    + +P        T     +  LLGLLGA +G+              
Sbjct: 1   MRAVSFKLSGKFAHFKKPDVNEYAYFTYNNIPKPTLLGLLGAIIGLKGYAQKTYKDKKDK 60

Query: 47  -----------QRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDY 95
                      + +    L+ L   +   V+        +  +                Y
Sbjct: 61  KSLFNNENSSNEPEFYERLKHLKICIIPLVKYGRFSKKIQIFNNGV------------GY 108

Query: 96  RGLKSHETIQTWREYLCDASFTVALWLTPHATMVISELEKAV--LKPRYTPYLGRRSCPL 153
              +    +    ++L + S+ + +     A      + + +   K ++ PYLG+     
Sbjct: 109 ASGEDGGNLIVREQWLENPSWQILIEDDGSAE--FETVSRYLFDKKAKFIPYLGKNDHFA 166

Query: 154 THPLFLGTCQASDPQKALLNYEPVGGDIYSEESVTGHHLKFTARD-EPMITLPRQF 208
                     A   +  +        D+  +       + +   +  P+      F
Sbjct: 167 DISEVEKIDLAESKKDRISIKSLFLDDLAEQVDDPDDEISYLFNEFYPISFNELMF 222


>UniRef50_B9L1B8 CRISPR-associated protein Cas5, Tneap subtype n=1
           Tax=Thermomicrobium roseum DSM 5159 RepID=B9L1B8_THERP
          Length = 235

 Score = 52.0 bits (123), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 26/143 (18%), Positives = 45/143 (31%), Gaps = 23/143 (16%)

Query: 7   LRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVR 66
           +RL     ++  P+F   + +   P  + + GLL A  G        +  L+  + +A R
Sbjct: 8   IRLTALTASFRAPSFVAYQLSLAVPPLATIFGLLSAARG-HWVMPHEVPWLAYRLTYAAR 66

Query: 67  CDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPHA 126
             +L                     ++     +  E     RE+L      + L      
Sbjct: 67  AMDLEAIYSVER-------------KDAADTPRFKERNIVQREFLVSPELDLFLPAEWRD 113

Query: 127 TMVISELEKAVLKPRYTPYLGRR 149
                      L+PRY   LGR 
Sbjct: 114 P---------FLRPRYQLVLGRS 127


>UniRef50_C5U6V3 CRISPR-associated protein Cas5 family n=6 Tax=Euryarchaeota
           RepID=C5U6V3_9EURY
          Length = 215

 Score = 51.6 bits (122), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 30/148 (20%), Positives = 44/148 (29%), Gaps = 30/148 (20%)

Query: 4   YLILRLAGPMQAWGQPTFEG-TRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
            + ++L      +  PTF+   +PT   P  S +LGLL A  G        +  L +   
Sbjct: 1   MIRVKLKSWTATFRYPTFQSGYQPTLPLPPISTILGLLSAAKG-------EIVNLEDVEF 53

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWL 122
           F                  L                   +T    RE+L +   T+ L+L
Sbjct: 54  FGYIFKSEGKGVDLEKTYYL-------------SNENEVKTDVIRREFLFNN--TLYLYL 98

Query: 123 TPHATMVISELEKAVLKPRYTPYLGRRS 150
                            PRY   LGR  
Sbjct: 99  PDGWKTY-------FKSPRYQLLLGRSC 119


>UniRef50_UPI0001693F6C hypothetical protein Plarl_07470 n=1 Tax=Paenibacillus larvae
           subsp. larvae BRL-230010 RepID=UPI0001693F6C
          Length = 266

 Score = 51.6 bits (122), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 30/174 (17%), Positives = 48/174 (27%), Gaps = 22/174 (12%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRP-TGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
              L   L G    + +P        T     +  L GL GA +G+     S     +  
Sbjct: 1   MRALRFELKGETAFFKKPDVNVYAYFTYSHIHKVALYGLFGAIIGL--GGYSQQYERNHP 58

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSH---------------ETIQ 105
           +    R +  I           RD    +    D                        + 
Sbjct: 59  LTSNRRKNSEIKAVFPEFYEVFRDTSVCIVPHGDRGYFAKKIQIFNNTVGYASQEVGGVL 118

Query: 106 TWRE-YLCDASFTVALWLTPH-ATMVISELEKAVLKPR--YTPYLGRRSCPLTH 155
             RE +L    +T+ +         V   L   +L  +  Y PYLG+   P + 
Sbjct: 119 NVREQWLEHPHWTIYVAEDEGIPQPVFDRLADYILHSKAEYCPYLGKNDHPASL 172


>UniRef50_C8K6I7 Crispr-associated protein cas5 n=1 Tax=Listeria monocytogenes FSL
           R2-503 RepID=C8K6I7_LISMO
          Length = 240

 Score = 51.6 bits (122), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 19/149 (12%), Positives = 43/149 (28%), Gaps = 12/149 (8%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M   + +R+      + +      + +   P  S ++G++    G   D    +    + 
Sbjct: 1   MVRAIRVRIHQDSANYKKKMSFQLKESFPLPPFSTVIGMVHVACGF--DSYHEMDISVQG 58

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
             F    D     +          +H   G     RG+ +          L +    + +
Sbjct: 59  NYFNTFNDLYTRYEFGNKKFEKGRHHINAGGLGVTRGVATVN-------LLNNIDLLIHI 111

Query: 121 WLTPHATMVISELEKAVLK-PRYTPYLGR 148
              P        +  ++ + P     LGR
Sbjct: 112 --IPKKEEDFELILNSLRRMPTRFLSLGR 138


>UniRef50_A6DAF2 Putative uncharacterized protein n=1 Tax=Caminibacter
           mediatlanticus TB-2 RepID=A6DAF2_9PROT
          Length = 233

 Score = 50.8 bits (120), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 19/149 (12%), Positives = 44/149 (29%), Gaps = 10/149 (6%)

Query: 2   RSYLILRLAGPMQAWGQPTFE-GTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
              +   L+G    + +P        T     +  LLG+ GA LG+   +          
Sbjct: 1   MKAISFNLSGKFAHFKKPDVNSNVYFTYSHIHKIALLGIFGAILGLDGYNKDIKDYPEFY 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
            +      + +                       Y   +    +    ++L + ++ + +
Sbjct: 61  KRL-----KHLKVSIIPKEVMFSKKIITFNNSVGYASKEQGGNLVVKEQWLENPAWEILV 115

Query: 121 WLTPHATMVISELEKAV--LKPRYTPYLG 147
                     ++L + +   +  Y PYLG
Sbjct: 116 KDDGSDK--FNKLREKLFNKECVYIPYLG 142


>UniRef50_A8TI38 CRISPR-associated protein Cas5 family n=1 Tax=Methanococcus voltae
           A3 RepID=A8TI38_METVO
          Length = 248

 Score = 50.8 bits (120), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 26/151 (17%), Positives = 46/151 (30%), Gaps = 29/151 (19%)

Query: 2   RSYLILRLAGPMQAWGQPTFEG-TRPTGRFPTRSGLLGLLGACLGIQ--RDDTSSLQALS 58
              L ++       +  P     T  +   P  S ++G++ +C+G +  RD+T       
Sbjct: 1   MKLLHVQFQAYTATFKMPNINSGTMVSIPVPLYSTIVGIISSCMGRELQRDETKI----- 55

Query: 59  ESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV 118
                                  L   H      +     ++ E   T RE+       +
Sbjct: 56  -----------GFKYSYENKGKDLETTH--RLKYDGGLLKQNSENSVTAREFHIKPILDI 102

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGRR 149
            L            L++  L P +TP LGR 
Sbjct: 103 YLSNLN--------LKEYFLNPVWTPSLGRS 125


>UniRef50_B7JW17 CRISPR-associated protein DevS n=2 Tax=Cyanobacteria
           RepID=B7JW17_CYAP8
          Length = 212

 Score = 50.8 bits (120), Expect = 4e-05,   Method: Composition-based stats.
 Identities = 19/154 (12%), Positives = 45/154 (29%), Gaps = 22/154 (14%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M + L++ L  P   + +        T   P  + + G+L + +G    +T   +     
Sbjct: 1   MNTPLVIYLDVPFVTFREFHAREMGRTYPVPPPATVYGMLLSLVG----ETDVYRHCGVE 56

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           +  A       +         LR         +      +     +++E L +    + +
Sbjct: 57  LAIA-------MLSEAKKSRILRQM----RRFKQKDFSHAENVNPSYQEILSNLKCLIWV 105

Query: 121 WLTPH--ATMVISELEKAVLKPRY-----TPYLG 147
                     +   +E    +P         +LG
Sbjct: 106 RSEAEMMQPSLKERIEFTFERPELVRRFGCLFLG 139


>UniRef50_A6UNR9 CRISPR-associated protein Cas5, Hmari subtype n=2 Tax=Methanococcus
           RepID=A6UNR9_METVS
          Length = 225

 Score = 50.4 bits (119), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 21/151 (13%), Positives = 45/151 (29%), Gaps = 18/151 (11%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              ++         + +P    +  T          GL+GA +GI + D   L   ++ +
Sbjct: 1   MKSVVFSAKSEYGRFRKPYTTTSALTFLCIHPVAAKGLIGALVGIDKLD---LYEETKDL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +  +                 +D  +V                 +  E+L    +   + 
Sbjct: 58  KIGIEVL----------GEINKDLQSVKLLNLKEGVSGGMFHFPSNIEFLRCPHYRFYVM 107

Query: 122 LTPHATMVISELEKAVL--KPRYTPYLGRRS 150
                   ++EL   +   +  +TPYLG   
Sbjct: 108 W---NENKLNELNDKLNVGEWEFTPYLGVSE 135


>UniRef50_C4IBN8 CRISPR-associated protein Cas5 n=5 Tax=Bacteria RepID=C4IBN8_CLOBU
          Length = 262

 Score = 50.0 bits (118), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 26/167 (15%), Positives = 50/167 (29%), Gaps = 32/167 (19%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRP-TGRFPTRSGLLGLLGACLGIQR------------ 48
              L   L G    + +P        T     +  L GLLGA LG               
Sbjct: 1   MRILKFTLRGKSGFFKKPDVNSNLYFTYGNIHKVALTGLLGAVLGYGGYNSMNIKNIFNK 60

Query: 49  ------DDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHE 102
                  D        + ++ ++                 +       +   Y   +   
Sbjct: 61  KKKEAVQDFPEFYERLKDLKISI-------VPNGEKGFISKKVQIFNNSV-GYASKEQGG 112

Query: 103 TIQTWREYLCDASFTVALWLTPHATMVISELEKAV--LKPRYTPYLG 147
            +    ++L + S+ + + +    +    ++E+A+   K  YTPYLG
Sbjct: 113 NLIVKEQWLENPSWDIYIIIDDEES---EKIEEAITKHKTVYTPYLG 156


>UniRef50_B4U1Q4 CRISPR-associated protein Cas5, Dvulg subtype n=12
           Tax=Streptococcus RepID=B4U1Q4_STREM
          Length = 239

 Score = 48.5 bits (114), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 38/223 (17%), Positives = 68/223 (30%), Gaps = 52/223 (23%)

Query: 7   LRLAGPMQAWGQPTF--EGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           +R+ G +  +  P       R +   PTR  L G++         D    +    +V   
Sbjct: 1   MRVRGDIALFTNPATKGSSERSSYPVPTRQALQGIV---------DAVYHKPTITNVVTE 51

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV---ALW 121
           V+    I  +   +   L+DY                    ++  YL D  + +    +W
Sbjct: 52  VKVINQIQTELHGTRALLKDY----------------GADLSYVSYLSDVEYLIKYHFVW 95

Query: 122 LTPHATMVISEL--------EKAVLK-PRYTPYLGRRSCPLTHPLFLGTCQASDPQ--KA 170
                 +V   L        E+++ K  R   +LG R C       LG  +A   +  + 
Sbjct: 96  NENRPDLVKDRLPNKHEAIMERSLRKGGRRDVFLGTREC-------LGLVEAISQEEYET 148

Query: 171 LLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREW 213
                           +       T R EP+    R + +R  
Sbjct: 149 AQIASEHANQEIDLGIMFHSFAYPTDRKEPL----RSYFTRTV 187


>UniRef50_C1DUL8 Crispr-associated protein Cas5, tneap subtype n=2 Tax=Aquificales
           RepID=C1DUL8_SULAA
          Length = 236

 Score = 48.1 bits (113), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 21/154 (13%), Positives = 44/154 (28%), Gaps = 23/154 (14%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L ++       + +P       +   P  S + G     +G+  +    +    +  
Sbjct: 1   MKLLKIKAYQIFANYRKPMSFNFWDSYPLPPLSTVRGWFHTTIGV--NQYIPIAMSIQGK 58

Query: 62  QFAVRCD-----ELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASF 116
             +V  D     +      +     L  ++ V      Y               + D S 
Sbjct: 59  FSSVVHDLQTLIKFDRKRDKERGIFLEGFNKVFSKSPTYVVN------------IYDISL 106

Query: 117 TVALWLTPHATMVISELEKAVLKPRYTPYLGRRS 150
           T+ L         +   ++ +LK  Y   LGR+ 
Sbjct: 107 TIYLKA---KEEYLKLFKENLLKNEYP-SLGRKE 136


>UniRef50_C2HJA9 Putative uncharacterized protein n=1 Tax=Finegoldia magna ATCC
          53516 RepID=C2HJA9_PEPMA
          Length = 361

 Score = 47.3 bits (111), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 7/45 (15%), Positives = 15/45 (33%)

Query: 2  RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGI 46
             L +++     ++ +        T   P  S ++G L    G 
Sbjct: 1  MKILRIKIKQAQASYTREETVDNHTTYPLPPFSTIIGALHNACGY 45


>UniRef50_A5N0X1 Putative uncharacterized protein n=2 Tax=Clostridium kluyveri
           RepID=A5N0X1_CLOK5
          Length = 246

 Score = 45.8 bits (107), Expect = 0.001,   Method: Composition-based stats.
 Identities = 26/218 (11%), Positives = 64/218 (29%), Gaps = 15/218 (6%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRP-TGRFPTRSGLLGLLGACLGIQR---DDTSSLQAL 57
              +  +L+G    + +P        T     +  LLG++G+ LG+             +
Sbjct: 1   MKAVRFKLSGRTAFFKKPDVNTYYYFTYGNIHKIALLGIIGSVLGLPGYNSQSRDFKNNI 60

Query: 58  SESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFT 117
                  ++  ++ +          +   T   +   Y  L++   +    ++L +  + 
Sbjct: 61  YPEFYNRLKDSKVAVVMLNHQGYITKKIQTFNNSV-GYASLEAGGNLVVKEQWLQEPKWM 119

Query: 118 VALWLTPHATMVISELEKAV--LKPRYTPYLGRRSCPLT----HPLFLGTCQASDPQKAL 171
           V + +      +  +    +   K  + PYLG+            + L   +      +L
Sbjct: 120 VYVKVD----EITEKFAHMLLHKKAIFLPYLGKNDHFADITEIKEVELEKSENYIKINSL 175

Query: 172 LNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFA 209
                   + Y EE               +     Q+ 
Sbjct: 176 FESRYFQVEKYQEEEDDTAWKYMEYLPVELDEELNQYR 213


>UniRef50_C6A4J5 Putative uncharacterized protein n=1 Tax=Thermococcus sibiricus MM
           739 RepID=C6A4J5_THESM
          Length = 218

 Score = 45.4 bits (106), Expect = 0.001,   Method: Composition-based stats.
 Identities = 24/199 (12%), Positives = 53/199 (26%), Gaps = 21/199 (10%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M   + + +   +  +   T    R +   P  + +LG   + LG  R+       L E 
Sbjct: 1   MEKGVTIDVLFDLAHFKVHTTMKGRTSYLIPLPTTVLGFFFSILGKGREAY-----LRER 55

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
            QF     +       +      +   +   R                  L    +  A+
Sbjct: 56  NQF-----KAGAKLLSIKGIARENAQLLKLKRGQEVRTTEELM------LLVKPKYRFAI 104

Query: 121 WLTPHATMVISELEKAVL--KPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVG 178
           W       +I+ L + V      + PY G     ++           + +  + +     
Sbjct: 105 W---GKQELINNLYERVRTFDFEFVPYGGISEFIISEIETPQLYDEYEEKDTIKDSYVPQ 161

Query: 179 GDIYSEESVTGHHLKFTAR 197
             + S   +    +     
Sbjct: 162 PLLNSLRILDNGIVYNLPY 180


>UniRef50_C9XQW2 Crispr-associated protein cas5 family n=2 Tax=Clostridium difficile
           RepID=C9XQW2_CLODC
          Length = 215

 Score = 45.4 bits (106), Expect = 0.002,   Method: Composition-based stats.
 Identities = 21/151 (13%), Positives = 41/151 (27%), Gaps = 35/151 (23%)

Query: 7   LRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVR 66
           + + G M  +  P     + T   P  S ++G+L    G + DD          + + + 
Sbjct: 6   IEIIGDMAHFKIPMHSKIQRTYEIPPISTVVGILKNIYGEEIDDF--------ILGYVIY 57

Query: 67  CDELILDDRRVSVTGLRDYHTVLGAREDYRG----LKSHETIQTWREYLCDASFTVALWL 122
            D              +D  T+                 +T     EYL +    +   +
Sbjct: 58  HD-----------GTFKDLQTIYKEINPNVKTLTDSDRFQTDVCPIEYLINPKLIIYTNI 106

Query: 123 TPHATMVISELEKAVLKPRYTPYLGRRSCPL 153
             +                    LG+ +C  
Sbjct: 107 DKNIEFN------------EPLCLGKTNCLA 125


>UniRef50_Q8F1E3 Fruiting body developmental protein S-like protein n=2
          Tax=Leptospira interrogans RepID=Q8F1E3_LEPIN
          Length = 207

 Score = 44.6 bits (104), Expect = 0.002,   Method: Composition-based stats.
 Identities = 10/48 (20%), Positives = 19/48 (39%)

Query: 2  RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRD 49
             LIL    P+ ++        + +   P  S L+G+  +  G+  D
Sbjct: 1  MDPLILYYEIPIASFRPYQSREYQDSYPVPPPSTLIGMSLSLCGLSMD 48


>UniRef50_A5TU43 Putative uncharacterized protein n=3 Tax=Fusobacterium
          RepID=A5TU43_FUSNP
          Length = 366

 Score = 42.3 bits (98), Expect = 0.011,   Method: Composition-based stats.
 Identities = 8/45 (17%), Positives = 14/45 (31%)

Query: 2  RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGI 46
             L + L      + +      + T   P  S ++G L    G 
Sbjct: 1  MEALRIILKQSSANYRKAGTVDNKMTYPLPIPSTIIGALHNICGY 45


>UniRef50_B5YAX9 CRISPR-associated protein Cas5, Tneap subtype n=1 Tax=Dictyoglomus
           thermophilum H-6-12 RepID=B5YAX9_DICT6
          Length = 233

 Score = 42.3 bits (98), Expect = 0.012,   Method: Composition-based stats.
 Identities = 23/154 (14%), Positives = 43/154 (27%), Gaps = 27/154 (17%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L L++      + +P       T   PT S + G +   L            LS S+
Sbjct: 1   MKVLKLKVYQQFANYRKPLSYSFIDTFPLPTYSNIRGWIHRIL-----QAQEYIPLSISI 55

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKS-------HETIQTWREYLCDA 114
           Q                 + + D  T           K         +TI     Y+ + 
Sbjct: 56  Q-------------GTYESIVYDLQTFYKFDRPRPEKKDLIFLPEYKKTIVKSPFYVANL 102

Query: 115 SFTVALWLTPHATMVISELEKAVLKPRYTPYLGR 148
                +        ++ +++  +L     P +GR
Sbjct: 103 QNVSLILHINMEYSLLEKIKTMLLDTF--PSIGR 134


>UniRef50_B6WA84 Putative uncharacterized protein n=2 Tax=Anaerococcus
           RepID=B6WA84_9FIRM
          Length = 245

 Score = 41.9 bits (97), Expect = 0.014,   Method: Composition-based stats.
 Identities = 24/161 (14%), Positives = 46/161 (28%), Gaps = 32/161 (19%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGT-RPTGRFPTRSGLLGLLGACL------------GIQR 48
              L  RL+G    + QP        T          G +                G   
Sbjct: 1   MKALRFRLSGKTGFFKQPDVNTYLYYTY---------GQIHRVALLGLLGATLGYKGYNE 51

Query: 49  DDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWR 108
            D        + +    R  ++ +     +    R           +   +    +   +
Sbjct: 52  KDREKYPEFYKKL----RDLKISVVSEGNNGVFDRKLQ-AFNNSTAFASNEEGGNLIVKQ 106

Query: 109 EYLCDASFTVALWLTPHATMVISE--LEKAVLKPRYTPYLG 147
            +L + S+ + + L    + +I E  L+    K  +TPYLG
Sbjct: 107 VWLENPSWLIYILLDNDQSELIKEYILD---KKTTFTPYLG 144


>UniRef50_A9GDF4 Fruiting body developmental protein S n=2 Tax=Bacteria
           RepID=A9GDF4_SORC5
          Length = 224

 Score = 40.4 bits (93), Expect = 0.041,   Method: Composition-based stats.
 Identities = 31/217 (14%), Positives = 62/217 (28%), Gaps = 35/217 (16%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
            + +R+  P  ++ +        +  F   + + G+L + +G +          S +   
Sbjct: 1   MITVRVQAPYASFRRSYARSFAESYPFAPPATVYGMLLSLVGER----------SRARHV 50

Query: 64  AVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLT 123
            VR          V+ T  +               +       + E LC   F   +  +
Sbjct: 51  GVRLAFAYARQPAVATTLRK---LSRYKYGVATKQEKLGNAPDFVETLCGLDFLCWIDSS 107

Query: 124 PH---------ATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNY 174
                         +   +E+AVL P      G         + LG   + D   A+   
Sbjct: 108 GEVGAARHGAAVARLEERVERAVLSPETVTRSGI--------VCLGL--SDDAVDAVTLV 157

Query: 175 EPVGGDIYS---EESVTGHHLKFTARDEPMITLPRQF 208
               G   S   +E+       +      + T  R+F
Sbjct: 158 RRPEGRWRSLVPDEAGEVELPTWVDHVGSLDTRWRRF 194


>UniRef50_C0D371 Putative uncharacterized protein n=1 Tax=Clostridium asparagiforme
           DSM 15981 RepID=C0D371_9CLOT
          Length = 200

 Score = 39.6 bits (91), Expect = 0.081,   Method: Composition-based stats.
 Identities = 28/206 (13%), Positives = 59/206 (28%), Gaps = 15/206 (7%)

Query: 6   ILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ-FA 64
              +AGP  ++ +P    +  +   PTRS ++G++       R+     + +        
Sbjct: 9   AFEVAGPAASYARPDAGSSPISSAVPTRSAIIGMMTCV-AFSREAYFWPERIELCAHPMY 67

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTP 124
            R  +      R S    +   TVL   +                 L +    +      
Sbjct: 68  HRYTQNYNGPLRKSQAPFQIMATVLINVDYKIYGTVKGYAPPTA--LHNPMHQLR----- 120

Query: 125 HATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDIYSE 184
              + +  L+  +     TP LG      +   F      +   + +    P   D   +
Sbjct: 121 --DVFMRRLKSGL--FYRTPSLGLSEFIPS--YFGPLRDDTQVDRTINLEIPSLLDTMFD 174

Query: 185 ESVTGHHLKFTARDEPMITLPRQFAS 210
               G       ++  ++     FA 
Sbjct: 175 RPTDGQLSPTFMQNVKIVEGVLHFAE 200


>UniRef50_Q8TYH7 Coenzyme F420-reducing hydrogenase, beta subunit n=1
           Tax=Methanopyrus kandleri RepID=Q8TYH7_METKA
          Length = 377

 Score = 39.3 bits (90), Expect = 0.092,   Method: Composition-based stats.
 Identities = 26/188 (13%), Positives = 51/188 (27%), Gaps = 16/188 (8%)

Query: 42  ACLGIQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSH 101
           A  G    +        + V   V  +          +          G+        + 
Sbjct: 25  AACGGVVTELLRHALREDLVDVVVCVERGADALDGRPIVVDDPAEVPSGSYHCAPTQLAR 84

Query: 102 ETIQTWREYLCDASFTVALWLTPHATMVISELEKA-VLKPRYTPYLGRRSCPLTHPLFLG 160
              +  RE   D +  VA+   P     +  L +  ++ P     +G            G
Sbjct: 85  LVAELHRE---DPTLRVAVTCRPCDARTLDRLAERDLVNPDRVYRIGLNC--------GG 133

Query: 161 TCQASDPQKALLNYEPVGGDIYSEESVTGHHLKFTAR----DEPMITLPRQFASREWYVI 216
           T +     + L  +     D+  EE V GH +            +  L  Q + R     
Sbjct: 134 TFEPRVVLEILEEHGVDPLDVEREEVVKGHLVIELRDGEEISVSIDELEEQDSGRRENCR 193

Query: 217 KGGMDVSQ 224
           +   ++ +
Sbjct: 194 RCDENIPE 201


Searching..................................................done


Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_Q46898 Uncharacterized protein ygcI n=13 Tax=Proteobact...   213   4e-54
UniRef50_D1NTI1 CRISPR-associated protein Cas5 n=1 Tax=Bifidobac...   180   4e-44
UniRef50_B7KJ26 CRISPR-associated protein Cas5 family n=1 Tax=Cy...   173   5e-42
UniRef50_Q314I4 CRISPR-associated protein, CT1976 n=1 Tax=Desulf...   170   3e-41
UniRef50_Q12YA8 CRISPR-associated protein, CT1976-like n=1 Tax=M...   169   6e-41
UniRef50_D1CGD4 CRISPR-associated protein Cas5 family n=6 Tax=Ba...   165   1e-39
UniRef50_A1ARH6 CRISPR-associated protein, Cas5e family n=2 Tax=...   164   3e-39
UniRef50_Q47PI7 CRISPR-associated protein, Cas5e family n=12 Tax...   163   4e-39
UniRef50_A3EQA4 CRISPR-ssociated protein, Cas5 n=3 Tax=Bacteria ...   163   4e-39
UniRef50_A8M404 CRISPR-associated protein Cas5 family n=1 Tax=Sa...   163   5e-39
UniRef50_Q5YRB6 Putative uncharacterized protein n=1 Tax=Nocardi...   162   9e-39
UniRef50_D0WFC8 CRISPR-associated protein Cas5 n=1 Tax=Slackia e...   159   5e-38
UniRef50_Q1R114 CRISPR-associated protein, CT1976 n=1 Tax=Chromo...   159   5e-38
UniRef50_A6W168 CRISPR-associated protein Cas5 family n=6 Tax=Ga...   159   9e-38
UniRef50_A7BA63 Putative uncharacterized protein n=1 Tax=Actinom...   159   9e-38
UniRef50_B8HWH8 CRISPR-associated protein Cas5 family n=1 Tax=Cy...   157   2e-37
UniRef50_B0TDU1 Crispr-associated protein cas5 n=1 Tax=Heliobact...   155   7e-37
UniRef50_Q1EQS9 CRISPR-associated protein n=3 Tax=Streptomyces R...   155   1e-36
UniRef50_C7LYW6 CRISPR-associated protein Cas5 family n=1 Tax=Ac...   154   3e-36
UniRef50_A5GBK2 CRISPR-associated protein Cas5 family n=2 Tax=De...   153   4e-36
UniRef50_Q03C60 CRISPR-associated protein n=4 Tax=Lactobacillus ...   153   4e-36
UniRef50_A8SDR7 Putative uncharacterized protein n=1 Tax=Faecali...   153   5e-36
UniRef50_Q0W584 Putative uncharacterized protein n=1 Tax=uncultu...   152   6e-36
UniRef50_B1VIY0 CRISPR-associated protein n=9 Tax=Actinomycetale...   152   9e-36
UniRef50_C8XAY4 CRISPR-associated protein Cas5 family n=2 Tax=Ac...   152   1e-35
UniRef50_Q04QB7 Putative uncharacterized protein n=2 Tax=Leptosp...   151   2e-35
UniRef50_D0Y918 CRISPR-associated protein Cas5 family n=2 Tax=De...   151   2e-35
UniRef50_C2BET8 CRISPR-associated protein n=2 Tax=Firmicutes Rep...   150   2e-35
UniRef50_Q2JWC5 CRISPR-associated protein Cas5, Ecoli subtype n=...   150   3e-35
UniRef50_D1CAJ0 CRISPR-associated protein Cas5 family n=1 Tax=Sp...   150   5e-35
UniRef50_UPI0001AF1D4C CRISPR-associated protein, CT1976 n=1 Tax...   149   5e-35
UniRef50_C7MQD6 CRISPR-associated protein Cas5 n=1 Tax=Saccharom...   149   6e-35
UniRef50_D2L2X8 CRISPR-associated protein Cas5 family n=1 Tax=De...   149   1e-34
UniRef50_B4S8P8 CRISPR-associated protein Cas5 family n=8 Tax=Ba...   148   1e-34
UniRef50_A1SV73 CRISPR-associated protein, Cas5e family n=2 Tax=...   148   1e-34
UniRef50_Q2RY19 CRISPR-associated protein, Cas5e family n=1 Tax=...   148   1e-34
UniRef50_D2RB02 CRISPR system CASCADE complex protein CasD n=3 T...   147   4e-34
UniRef50_B2GBJ9 Putative uncharacterized protein n=1 Tax=Lactoba...   146   4e-34
UniRef50_C5SD48 CRISPR-associated protein Cas5 family n=1 Tax=Al...   146   5e-34
UniRef50_A8LYZ7 CRISPR-associated protein Cas5 family n=2 Tax=Ac...   146   5e-34
UniRef50_B8GIV3 CRISPR-associated protein Cas5 family n=1 Tax=Me...   145   7e-34
UniRef50_C9M2Y8 CRISPR-associated protein n=1 Tax=Lactobacillus ...   145   9e-34
UniRef50_A8ZZ17 CRISPR-associated protein Cas5 family n=1 Tax=De...   145   1e-33
UniRef50_A5UR14 CRISPR-associated protein, Cas5e family n=1 Tax=...   144   2e-33
UniRef50_D1A6Q5 CRISPR-associated protein Cas5 family n=2 Tax=Ac...   144   2e-33
UniRef50_C7MTB0 CRISPR-associated protein Cas5 n=1 Tax=Saccharom...   144   3e-33
UniRef50_Q2JH27 CRISPR-associated protein, CT1976 n=6 Tax=Actino...   143   4e-33
UniRef50_B0S4B6 Putative uncharacterized protein n=1 Tax=Finegol...   143   4e-33
UniRef50_B3E5U9 CRISPR-associated protein Cas5 family n=2 Tax=De...   142   9e-33
UniRef50_D0MET6 CRISPR-associated protein Cas5 family n=1 Tax=Rh...   139   9e-32
UniRef50_C9M9R7 CRISPR-associated protein Cas5, Ecoli subtype n=...   139   1e-31
UniRef50_Q1J367 CRISPR-associated protein, CT1976 n=1 Tax=Deinoc...   137   2e-31
UniRef50_Q0BSC7 Putative uncharacterized protein n=1 Tax=Granuli...   137   2e-31
UniRef50_B4UE71 CRISPR-associated protein Cas5 family n=2 Tax=An...   137   4e-31
UniRef50_Q0AA33 CRISPR-associated protein Cas5 family n=2 Tax=Ga...   136   4e-31
UniRef50_A7ZDW7 Crispr-associated protein Cas5 n=3 Tax=Campyloba...   136   6e-31
UniRef50_A9HLC6 CRISPR-associated protein Cas5 family n=11 Tax=A...   134   2e-30
UniRef50_B8IZA7 CRISPR-associated protein Cas5 family n=1 Tax=De...   133   6e-30
UniRef50_Q3AA65 CRISPR-associated protein Cas5, Hmari subtype n=...   132   8e-30
UniRef50_Q2FNU0 CRISPR-associated protein, CT1976 n=1 Tax=Methan...   131   2e-29
UniRef50_B8FDI0 CRISPR-associated protein Cas5 family n=3 Tax=Ba...   128   1e-28
UniRef50_B4TTX2 CRISPR-associated protein Cas5 n=15 Tax=Enteroba...   128   2e-28
UniRef50_D1Y486 Crispr-associated protein Cas5 n=1 Tax=Pyramidob...   127   2e-28
UniRef50_B8IMR2 CRISPR-associated protein Cas5 family n=1 Tax=Me...   127   2e-28
UniRef50_B9MPU1 CRISPR-associated protein Cas5, Hmari subtype n=...   126   4e-28
UniRef50_B5YBH8 CRISPR-associated protein Cas5, Hmari subtype n=...   126   7e-28
UniRef50_C8PE23 CRISPR-associated protein Cas5 n=1 Tax=Campyloba...   125   8e-28
UniRef50_B0K553 CRISPR-associated protein Cas5, Hmari subtype n=...   125   1e-27
UniRef50_A5D0Y3 Putative uncharacterized protein n=1 Tax=Pelotom...   125   1e-27
UniRef50_Q1AZD3 CRISPR-associated protein, Cas5h family n=1 Tax=...   123   3e-27
UniRef50_B6B783 CRISPR-associated protein Cas5, Ecoli subtype n=...   123   3e-27
UniRef50_A3DKB9 CRISPR-associated protein Cas5, Hmari subtype n=...   123   4e-27
UniRef50_B5F422 CRISPR-associated protein Cas5 n=59 Tax=Enteroba...   123   5e-27
UniRef50_C5V9N1 CRISPR-associated protein Cas5 n=1 Tax=Corynebac...   122   1e-26
UniRef50_B5GY62 Crispr-associated protein (Fragment) n=1 Tax=Str...   121   2e-26
UniRef50_C1DUR1 Crispr-associated protein Cas5, hmari subtype n=...   120   3e-26
UniRef50_Q2NH81 Putative uncharacterized protein n=1 Tax=Methano...   120   4e-26
UniRef50_C2KP44 Putative uncharacterized protein n=1 Tax=Mobilun...   118   2e-25
UniRef50_D1CHV1 CRISPR-associated protein Cas5 n=1 Tax=Thermobac...   116   6e-25
UniRef50_B6XT64 Putative uncharacterized protein n=2 Tax=Bifidob...   114   2e-24
UniRef50_A7HLK6 CRISPR-associated protein Cas5, Hmari subtype n=...   113   4e-24
UniRef50_A7BQN4 Protein containing DUF522 n=1 Tax=Beggiatoa sp. ...   112   7e-24
UniRef50_A6TQ83 CRISPR-associated protein Cas5 family n=9 Tax=Ba...   112   9e-24
UniRef50_UPI00016C61FD CRISPR-associated protein Cas5, hmari sub...   111   2e-23
UniRef50_C0W6U0 CRISPR-associated Cas5 family protein n=1 Tax=Ac...   110   2e-23
UniRef50_Q8PZD2 Putative uncharacterized protein n=1 Tax=Methano...   110   3e-23
UniRef50_A6UVX6 CRISPR-associated protein Cas5, Hmari subtype n=...   110   4e-23
UniRef50_B8CYA3 CRISPR-associated protein Cas5 n=1 Tax=Halotherm...   110   4e-23
UniRef50_B6IWM3 CRISPR-associated protein, CT1976 family n=1 Tax...   110   4e-23
UniRef50_B1B9K0 Crispr-associated protein Cas5, tneap subtype n=...   110   5e-23
UniRef50_A3XI99 Putative uncharacterized protein n=1 Tax=Leeuwen...   109   7e-23
UniRef50_C5CFB1 CRISPR-associated protein Cas5, Hmari subtype n=...   108   1e-22
UniRef50_Q2RXJ5 CRISPR-associated protein, Cas5e family n=5 Tax=...   108   1e-22
UniRef50_Q6NEQ9 Putative uncharacterized protein n=1 Tax=Coryneb...   108   1e-22
UniRef50_B8IJS9 CRISPR-associated protein Cas5 family n=1 Tax=Me...   108   2e-22
UniRef50_B1L2N4 Crispr-associated protein Cas5, hmari subtype n=...   107   3e-22
UniRef50_C2GEY8 CRISPR-associated protein n=1 Tax=Corynebacteriu...   107   4e-22
UniRef50_C9RCY2 CRISPR-associated protein Cas5, Hmari subtype n=...   106   5e-22
UniRef50_A8F3P0 CRISPR-associated protein Cas5, Hmari subtype n=...   106   6e-22
UniRef50_C5VUI7 Crispr-associated protein Cas5, hmari subtype n=...   106   6e-22
UniRef50_A4J1X9 CRISPR-associated protein Cas5, Hmari subtype n=...   105   8e-22
UniRef50_C7NNV3 CRISPR-associated protein Cas5, Hmari subtype n=...   105   8e-22
UniRef50_C6QNG6 CRISPR-associated protein Cas5, Hmari subtype n=...   105   1e-21
UniRef50_C8VZL1 CRISPR-associated protein Cas5 n=1 Tax=Desulfoto...   105   1e-21
UniRef50_O27159 Putative uncharacterized protein n=1 Tax=Methano...   105   1e-21
UniRef50_C9M4F0 Putative uncharacterized protein n=1 Tax=Lactoba...   104   2e-21
UniRef50_A7VC52 Putative uncharacterized protein n=1 Tax=Clostri...   104   2e-21
UniRef50_A0B6V6 CRISPR-associated protein Cas5, Hmari subtype n=...   103   3e-21
UniRef50_B0VIK7 Putative uncharacterized protein n=1 Tax=Candida...   103   4e-21
UniRef50_C5D4M6 CRISPR-associated protein Cas5, Hmari subtype n=...   103   4e-21
UniRef50_B0ABR7 Putative uncharacterized protein n=1 Tax=Clostri...   103   4e-21
UniRef50_Q0AW00 CRISPR-associated protein, Cas5h family n=2 Tax=...   103   5e-21
UniRef50_A0RNQ4 Crispr-associated protein Cas5, hmari subtype n=...   103   5e-21
UniRef50_A4XGC7 CRISPR-associated protein Cas5 family n=1 Tax=Ca...   103   6e-21
UniRef50_C9RW51 CRISPR-associated protein Cas5, Hmari subtype n=...   103   6e-21
UniRef50_C9L3W3 CRISPR-associated protein Cas5, Tneap subtype n=...   101   2e-20
UniRef50_A8UUT1 Putative uncharacterized protein n=1 Tax=Hydroge...   100   3e-20
UniRef50_C7P9L3 CRISPR-associated protein Cas5 n=2 Tax=Methanoca...   100   3e-20
UniRef50_A5N0X1 Putative uncharacterized protein n=2 Tax=Clostri...   100   4e-20
UniRef50_B5YIV3 CRISPR-associated protein Cas5 n=1 Tax=Thermodes...   100   4e-20
UniRef50_B7R550 CRISPR-associated protein Cas5 n=1 Tax=Thermococ...   100   5e-20
UniRef50_UPI0000F51765 hypothetical protein Faci_00030 n=1 Tax=F...   100   6e-20
UniRef50_B8DAB1 Crispr-associated protein Cas5, tneap subtype n=...   100   7e-20
UniRef50_C1TQC8 CRISPR-associated protein Cas5, Hmari subtype n=...    99   8e-20
UniRef50_B1LAM2 CRISPR-associated protein Cas5, Hmari subtype n=...    99   1e-19
UniRef50_UPI0000F51712 CRISPR-associated Cas5 family Hmari subty...    99   1e-19
UniRef50_D2QT47 CRISPR-associated protein Cas5 n=1 Tax=Spirosoma...    99   1e-19
UniRef50_A3DHS3 CRISPR-associated protein Cas5 n=3 Tax=Clostridi...    99   2e-19
UniRef50_C3HBA5 Putative uncharacterized protein n=2 Tax=Bacillu...    98   2e-19
UniRef50_A4FXZ5 CRISPR-associated protein Cas5 n=1 Tax=Methanoco...    98   3e-19
UniRef50_B8DZH7 CRISPR-associated protein Cas5, Hmari subtype n=...    97   3e-19
UniRef50_B5IGN1 CRISPR-associated protein Cas5 n=1 Tax=Acidulipr...    97   4e-19
UniRef50_C1QDM0 CRISPR-associated protein Cas5 n=1 Tax=Brachyspi...    97   4e-19
UniRef50_B9D004 Crispr-associated protein Cas5 n=1 Tax=Campyloba...    97   5e-19
UniRef50_B7AS04 Putative uncharacterized protein n=1 Tax=Bactero...    97   5e-19
UniRef50_O66696 Putative uncharacterized protein n=2 Tax=Aquific...    97   6e-19
UniRef50_D1N0K0 Putative uncharacterized protein n=1 Tax=Victiva...    96   7e-19
UniRef50_D0MJ68 CRISPR-associated protein Cas5 n=1 Tax=Rhodother...    96   8e-19
UniRef50_A9BGY6 CRISPR-associated protein Cas5, Hmari subtype n=...    95   2e-18
UniRef50_UPI0001B51C2B CRISPR-associated Cas5 family protein n=1...    95   2e-18
UniRef50_B7GIV5 CRISPR system related protein, RAMP superfamily ...    95   2e-18
UniRef50_A1ZHZ1 Crispr-associated protein Cas5, hmari subtype n=...    94   3e-18
UniRef50_A6DAF2 Putative uncharacterized protein n=1 Tax=Caminib...    94   4e-18
UniRef50_A5ILM6 CRISPR-associated protein Cas5 family n=3 Tax=Th...    94   5e-18
UniRef50_Q12WX6 CRISPR-associated protein Cas5, Hmari subtype n=...    94   5e-18
UniRef50_B1BR50 Crispr-associated protein Cas5 n=1 Tax=Clostridi...    93   7e-18
UniRef50_A4XM40 CRISPR-associated protein Cas5 family n=3 Tax=Cl...    92   1e-17
UniRef50_Q1Q0Z9 Putative uncharacterized protein n=1 Tax=Candida...    92   1e-17
UniRef50_C4IBN8 CRISPR-associated protein Cas5 n=5 Tax=Bacteria ...    92   1e-17
UniRef50_O57910 Putative uncharacterized protein PH0171 n=1 Tax=...    92   1e-17
UniRef50_Q2NFS3 Putative uncharacterized protein n=1 Tax=Methano...    92   2e-17
UniRef50_A1HND7 CRISPR-associated protein Cas5 family n=1 Tax=Th...    92   2e-17
UniRef50_B9LWL0 CRISPR-associated protein Cas5, Hmari subtype n=...    91   2e-17
UniRef50_A7GQ89 CRISPR-associated protein Cas5 family n=1 Tax=Ba...    90   4e-17
UniRef50_UPI0001693F6C hypothetical protein Plarl_07470 n=1 Tax=...    90   4e-17
UniRef50_C9XLN6 Putative uncharacterized protein n=6 Tax=Clostri...    89   1e-16
UniRef50_C8K6I7 Crispr-associated protein cas5 n=1 Tax=Listeria ...    89   1e-16
UniRef50_A6UNR9 CRISPR-associated protein Cas5, Hmari subtype n=...    89   2e-16
UniRef50_D1B1G1 CRISPR-associated protein Cas5 n=1 Tax=Sulfurosp...    88   2e-16
UniRef50_C9XPZ9 Putative uncharacterized protein n=5 Tax=Clostri...    88   2e-16
UniRef50_B8FSG3 CRISPR-associated protein Cas5 n=4 Tax=Firmicute...    87   4e-16
UniRef50_A0LM54 Putative uncharacterized protein n=1 Tax=Syntrop...    86   1e-15
UniRef50_Q2RHQ8 Putative uncharacterized protein n=1 Tax=Moorell...    85   1e-15
UniRef50_D1QSA9 CRISPR-associated protein Cas5, Tneap subtype n=...    85   1e-15
UniRef50_B1I4M5 CRISPR-associated protein Cas5 family n=1 Tax=Ca...    82   1e-14
UniRef50_Q3M7D6 Fruiting body developmental protein S-like prote...    82   2e-14
UniRef50_A9WFZ3 CRISPR-associated protein Cas5 family n=6 Tax=Ch...    82   2e-14
UniRef50_A1ZVP9 Crispr-associated protein Cas5, tneap subtype n=...    80   6e-14
UniRef50_C1DUL8 Crispr-associated protein Cas5, tneap subtype n=...    80   6e-14
UniRef50_D1A6P6 Metal dependent phosphohydrolase n=1 Tax=Thermom...    80   6e-14
UniRef50_Q0ATZ7 CRISPR-associated protein, Cas5h family n=1 Tax=...    78   2e-13
UniRef50_B5YL08 CRISPR-associated protein Cas5 n=1 Tax=Thermodes...    77   3e-13
UniRef50_C6A4J5 Putative uncharacterized protein n=1 Tax=Thermoc...    76   9e-13
UniRef50_A8TI38 CRISPR-associated protein Cas5 family n=1 Tax=Me...    74   2e-12
UniRef50_B9L1B8 CRISPR-associated protein Cas5, Tneap subtype n=...    73   6e-12
UniRef50_B3EG03 CRISPR-associated protein Cas5 family n=4 Tax=ce...    72   1e-11
UniRef50_C0QHV7 Putative CRISPR-associated protein Cas5 n=1 Tax=...    71   2e-11
UniRef50_C5U6V3 CRISPR-associated protein Cas5 family n=6 Tax=Eu...    71   3e-11
UniRef50_C9XQW2 Crispr-associated protein cas5 family n=2 Tax=Cl...    70   4e-11
UniRef50_B1I5P1 CRISPR-associated protein Cas5 n=2 Tax=Clostridi...    67   5e-10
UniRef50_B4U1Q4 CRISPR-associated protein Cas5, Dvulg subtype n=...    65   2e-09
UniRef50_B7JW17 CRISPR-associated protein DevS n=2 Tax=Cyanobact...    60   8e-08
UniRef50_C2HJA9 Putative uncharacterized protein n=1 Tax=Finegol...    56   1e-06

Sequences not found previously or not previously below threshold:

UniRef50_B0M916 Putative uncharacterized protein n=4 Tax=Firmicu...    82   1e-14
UniRef50_A6LJX1 CRISPR-associated protein Cas5 n=1 Tax=Thermosip...    80   6e-14
UniRef50_D2QHQ8 CRISPR-associated protein Cas5, Hmari subtype n=...    74   4e-12
UniRef50_B6WA84 Putative uncharacterized protein n=2 Tax=Anaeroc...    72   1e-11
UniRef50_B7IEF3 Cas crispr-associated protein Cas5 n=1 Tax=Therm...    72   2e-11
UniRef50_C0QR10 Crispr-associated protein Cas5, tneap subtype n=...    66   7e-10
UniRef50_B5YAX9 CRISPR-associated protein Cas5, Tneap subtype n=...    64   3e-09
UniRef50_UPI0001C41C2E CRISPR-associated protein Cas5 Hmari subt...    64   5e-09
UniRef50_C6PRK1 CRISPR-associated protein Cas5 n=1 Tax=Clostridi...    63   8e-09
UniRef50_A0Q255 Putative uncharacterized protein n=4 Tax=Bacteri...    56   1e-06
UniRef50_C6DXZ6 Crispr-associated protein Cas5 n=2 Tax=root RepI...    53   7e-06
UniRef50_A5TU43 Putative uncharacterized protein n=3 Tax=Fusobac...    53   8e-06
UniRef50_C3WMW5 Putative uncharacterized protein n=1 Tax=Fusobac...    52   1e-05
UniRef50_B1R9P4 Crispr-associated protein Cas5 n=5 Tax=Clostridi...    52   1e-05
UniRef50_D0GJK9 CRISPR-associated Cas5 family protein n=1 Tax=Le...    52   2e-05
UniRef50_Q74N42 NEQ020 n=1 Tax=Nanoarchaeum equitans RepID=Q74N4...    52   2e-05
UniRef50_Q1J1U3 CRISPR-associated protein, CT1134 n=3 Tax=Deinoc...    51   3e-05
UniRef50_B4VYG4 CRISPR-associated protein Cas5, Dvulg subtype n=...    50   5e-05
UniRef50_C6AL37 Crispr-associated protein Cas5, dvulg subtype n=...    50   7e-05
UniRef50_C8KYK7 CRISPR-associated RAMP Csd5d family protein n=4 ...    50   7e-05
UniRef50_Q8F1E3 Fruiting body developmental protein S-like prote...    49   1e-04
UniRef50_Q2J7P3 Putative uncharacterized protein n=1 Tax=Frankia...    49   1e-04
UniRef50_UPI0001BC6553 hypothetical protein FgonA2_03326 n=3 Tax...    49   1e-04
UniRef50_Q72WF9 CRISPR-associated protein, CT1134 family n=19 Ta...    48   2e-04
UniRef50_A5D0R8 Putative uncharacterized protein n=3 Tax=Bacteri...    48   2e-04
UniRef50_A9GDF4 Fruiting body developmental protein S n=2 Tax=Ba...    48   3e-04
UniRef50_C0D371 Putative uncharacterized protein n=1 Tax=Clostri...    48   3e-04
UniRef50_B8FSK6 CRISPR-associated protein Cas5 n=3 Tax=Clostridi...    47   7e-04
UniRef50_C5EH15 Crispr-protein cas5 family n=1 Tax=Clostridiales...    46   8e-04
UniRef50_Q1H3R5 CRISPR-associated protein, CT1134 n=14 Tax=Bacte...    46   0.001
UniRef50_Q3SR91 CRISPR-associated protein, Csd5d family n=17 Tax...    45   0.001
UniRef50_C1F2B9 CRISPR-associated protein Cas5, Dvulg subtype n=...    45   0.002
UniRef50_C4DD59 CRISPR-associated protein Cas5, Dvulg subtype n=...    43   0.006
UniRef50_A3J8H9 CRISPR-associated protein, CT1134 family n=2 Tax...    43   0.007
UniRef50_Q07766 Fruiting body developmental protein S n=1 Tax=My...    43   0.009
UniRef50_Q8TYH7 Coenzyme F420-reducing hydrogenase, beta subunit...    42   0.012
UniRef50_Q57827 Uncharacterized protein MJ0382 n=1 Tax=Methanoca...    42   0.013
UniRef50_Q2RL62 CRISPR-associated protein, CT1134 n=1 Tax=Moorel...    42   0.019
UniRef50_Q1CWU1 CRISPR-associated protein Cas5, Dvulg subtype n=...    41   0.032
UniRef50_B8IGC7 CRISPR-associated protein Cas5 n=1 Tax=Methyloba...    41   0.032
UniRef50_B7A743 Putative uncharacterized protein n=1 Tax=Thermus...    40   0.071

>UniRef50_Q46898 Uncharacterized protein ygcI n=13 Tax=Proteobacteria
           RepID=YGCI_ECOLI
          Length = 224

 Score =  213 bits (542), Expect = 4e-54,   Method: Composition-based stats.
 Identities = 224/224 (100%), Positives = 224/224 (100%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES
Sbjct: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL
Sbjct: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180
           WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD
Sbjct: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180

Query: 181 IYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVSQ 224
           IYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVSQ
Sbjct: 181 IYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVSQ 224


>UniRef50_D1NTI1 CRISPR-associated protein Cas5 n=1 Tax=Bifidobacterium gallicum DSM
           20093 RepID=D1NTI1_9BIFI
          Length = 250

 Score =  180 bits (456), Expect = 4e-44,   Method: Composition-based stats.
 Identities = 66/232 (28%), Positives = 101/232 (43%), Gaps = 28/232 (12%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            S LILRLAGPMQ+WG  +    R T   PT+S ++GLL +  G +R+D  S++ L   +
Sbjct: 1   MSVLILRLAGPMQSWGDSSRFNRRETRTEPTKSAVIGLLASAQGRRRED--SIEDLL-GL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +F VR D+            +RD+ T         G  S     T R YL DA F VA+ 
Sbjct: 58  RFGVRSDQ--------PGRIMRDFQTEKSIARKKSGEFSLTMPLTHRYYLADAKFLVAIE 109

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                  ++  L+ A+  P++  +LGRRSCP   P+ LG    ++ ++AL     +    
Sbjct: 110 ---GERSLLESLDAALRNPQWPLFLGRRSCPPASPVSLGVKDYANVEEALDKEPWIASPW 166

Query: 182 YSEE------------SVTGHHLKFTARDEPMITLP--RQFASREWYVIKGG 219
           Y ++            +V          D P+      R++A R        
Sbjct: 167 YRKKVHDSKRLQVVVDAVENGETTGQQSDMPLSFSQKHRRYAQRPVRRYFVD 218


>UniRef50_B7KJ26 CRISPR-associated protein Cas5 family n=1 Tax=Cyanothece sp. PCC
           7424 RepID=B7KJ26_CYAP7
          Length = 215

 Score =  173 bits (438), Expect = 5e-42,   Method: Composition-based stats.
 Identities = 67/228 (29%), Positives = 112/228 (49%), Gaps = 17/228 (7%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M   L+LRLAGP+Q+WG+ +    R T   PT+SG++GL+ A +GI RD+   L  L++ 
Sbjct: 1   MMKTLLLRLAGPLQSWGRGSRFDFRDTDTIPTKSGVIGLVAAAMGINRDNQVELAKLAQ- 59

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           ++  V  ++            + DYHTV+G      G      IQ++R+YLC+A F V L
Sbjct: 60  LRMGVCVEK--------EGKLVVDYHTVIGTIHA-DGKPHKAPIQSYRQYLCNAEFLVGL 110

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNY--EPVG 178
             +     +++E+E  +  P++  +LGR++CP + P+F+     +  + AL  Y    + 
Sbjct: 111 ESS--EYHLLNEIEHYLCFPKWELFLGRKACPPSKPIFVDLLT-NSLEDALYQYAISHLK 167

Query: 179 GDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIK--GGMDVSQ 224
              Y     +         D P+    R F++R     K     DVS+
Sbjct: 168 KGTYRLLIESKEPTGALRLDVPIDFKKRIFSARTVITPKPLEVSDVSE 215


>UniRef50_Q314I4 CRISPR-associated protein, CT1976 n=1 Tax=Desulfovibrio
           desulfuricans subsp. desulfuricans str. G20
           RepID=Q314I4_DESDG
          Length = 245

 Score =  170 bits (431), Expect = 3e-41,   Method: Composition-based stats.
 Identities = 75/238 (31%), Positives = 105/238 (44%), Gaps = 30/238 (12%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M  YL  ++ GP+QA+G       RPT   PTRS +LG+L A +GI+RD+ + L  L + 
Sbjct: 1   MAQYLTFQIYGPLQAYGTVAVGEIRPTSTMPTRSAVLGILAAAIGIRRDEETRLAELRDG 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGA----------REDYRGLKSHETIQTWREY 110
            + AVR D             + DYHT+             R D   L    TI + REY
Sbjct: 61  YRVAVRED--------APGKVMLDYHTIQTPGARGKRQLHCRRDELLLTEPNTILSRREY 112

Query: 111 LCDASFTVALW-LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQK 169
           L DA FTV LW         + E+ +A+  PR+T  LGR+SCP   P        + PQ+
Sbjct: 113 LMDALFTVCLWQANHTVPYSLQEIARALRSPRWTIGLGRKSCPPALPFAPKITDHTTPQE 172

Query: 170 ALLNYE-----------PVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVI 216
           A+  Y            P    +  +        + T RD P+    RQFA R+   +
Sbjct: 173 AVAAYPADKLVSAGLRSPQVMRMLLDTEGPHTDTETTVRDVPLHHGRRQFAERKVREL 230


>UniRef50_Q12YA8 CRISPR-associated protein, CT1976-like n=1 Tax=Methanococcoides
           burtonii DSM 6242 RepID=Q12YA8_METBU
          Length = 244

 Score =  169 bits (428), Expect = 6e-41,   Method: Composition-based stats.
 Identities = 63/251 (25%), Positives = 100/251 (39%), Gaps = 38/251 (15%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M+ YLI RL GPM +WG       RPT   P++S + GL+ A LGI+RD+      LS +
Sbjct: 1   MKEYLIFRLYGPMASWGDIAVGQHRPTYDHPSKSAIFGLIAAALGIRRDEEERHLELSNA 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAR---------------EDYRGLKSHETIQ 105
             +              +   LRDYHT                    E     +   T+ 
Sbjct: 61  YSYGTLI--------NSAGKLLRDYHTSQVPSAGTGRNRKTFATRKDELAVPKEELNTVL 112

Query: 106 TWREYLCDASFTVALWL-TPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQA 164
           + R+Y CD  +TV L   T      +  L  ++ +P +  YLGR+SCPL  P+      A
Sbjct: 113 STRDYYCDGVYTVILSCKTDTPPYSLELLGNSLKEPSFCLYLGRKSCPLALPINPKIVSA 172

Query: 165 SDPQKALLNYEPVGGDIYSEESVTGH--------------HLKFTARDEPMITLPRQFAS 210
           S+ ++AL + +P    +  +  +                     +  D+ +     QF+ 
Sbjct: 173 SNIKEALQSVDPGEEGLVKKIEMKSPYRLYWDDPKESMTCEHTISRYDKLLSRKRWQFSK 232

Query: 211 REWYVIKGGMD 221
           R  Y     ++
Sbjct: 233 RNEYYAMVSLE 243


>UniRef50_D1CGD4 CRISPR-associated protein Cas5 family n=6 Tax=Bacteria
           RepID=D1CGD4_THET1
          Length = 230

 Score =  165 bits (417), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 67/228 (29%), Positives = 105/228 (46%), Gaps = 25/228 (10%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L++RL+GPMQ+WG  +    R TGR P++SG++GL+ A LG  R   + +  L   +
Sbjct: 1   MPTLLMRLSGPMQSWGTQSRFTVRDTGREPSKSGVIGLICAALGRPRT--APVDDL-VRL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHET-----IQTWREYLCDASF 116
           +  VR D             +RDYHT  GA    R   +  T     +Q+ R YL DASF
Sbjct: 58  RMGVRVDR--------EGIVMRDYHTAGGAPAGERYGVATVTGDQRPVQSSRYYLADASF 109

Query: 117 TVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGT-------CQASDPQK 169
            VAL        ++ ++++A+  PR+  +LGR+SC  + P+ L          +  D + 
Sbjct: 110 LVALEGGEEDRPLLEQIDEALRAPRWQLFLGRKSCVPSEPIHLPKEPPLGPPIREEDLRT 169

Query: 170 ALLNYEPVGGDIYSEESVTGHHLKFTARDEPMIT--LPRQFASREWYV 215
           AL++Y    G             +    D P+      RQ+A+R    
Sbjct: 170 ALISYPWPEGAHRLRFVFEDPEGEELRNDVPISFEIGNRQYAARFVRT 217


>UniRef50_A1ARH6 CRISPR-associated protein, Cas5e family n=2 Tax=Bacteria
           RepID=A1ARH6_PELPD
          Length = 232

 Score =  164 bits (414), Expect = 3e-39,   Method: Composition-based stats.
 Identities = 59/233 (25%), Positives = 92/233 (39%), Gaps = 28/233 (12%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L+LRL GPMQ+WG  +    R TG+ P++SG++GLL A LGI R++   L+ L+  +
Sbjct: 1   MPTLLLRLVGPMQSWGTTSRFDQRDTGKEPSKSGVVGLLAAALGIDRENWVDLEPLT-CL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVL-----GAREDYRGLKSHETIQTWREYLCDASF 116
              VR D              RDY T          +          + + R YL DA+F
Sbjct: 60  AMGVRHDR--------PGVPKRDYQTAGCASTDTIIKADGTQAKGGGVVSQRFYLADAAF 111

Query: 117 TVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFL--GTCQASDPQKALLNY 174
            V L        ++  +  A+  P +T  LGR+S   +  +++  G   A    + L  Y
Sbjct: 112 LVGLEC--DDNCLLERIHVALHNPFWTLALGRKSYVPSESIWIVDGVRDAP-LLETLKRY 168

Query: 175 EPVGGDIYSEESVT--------GHHLKFTARDEPM-ITLPRQFASREWYVIKG 218
             +      EE                    D+P+     R+F +R       
Sbjct: 169 PWIASSRSREEPPERLLVSIESDDGAGVLKMDQPLSSFAERRFGARFVRSEWI 221


>UniRef50_Q47PI7 CRISPR-associated protein, Cas5e family n=12 Tax=Actinomycetales
           RepID=Q47PI7_THEFY
          Length = 245

 Score =  163 bits (413), Expect = 4e-39,   Method: Composition-based stats.
 Identities = 70/239 (29%), Positives = 101/239 (42%), Gaps = 36/239 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L L LAGP+QAWG  +    R T   PT+SG+LGLL A  G +R D   L  L+ ++
Sbjct: 1   MKVLTLLLAGPLQAWGAASRFTRRTTEHAPTKSGVLGLLAAAQGRERTD--DLSDLA-AL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +F VR D+          T +RD+ T +                + R YL DA F  A+ 
Sbjct: 58  RFGVRVDQ--------RGTRIRDFQTAIHLDTGKS------MPVSERFYLADAVFVAAVE 103

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                  +I  L +AV  P Y PYLGRRSCP + P+ LG       ++ L   +    + 
Sbjct: 104 ---GEDTLIDTLHQAVQHPVYLPYLGRRSCPPSRPINLGVHSGKPLEQVLAEEKWHAANW 160

Query: 182 YSE--------------ESVTGHHLKFTARDEPMITLP--RQFASREWYVIKGGMDVSQ 224
           Y                ++  G     + RD P+   P  R++A R    +   +   Q
Sbjct: 161 YQRQLRDLPEVPLDLLVDAPPGDPGADSLRDLPISFDPVHRRYALRGVRTLTVTVPNPQ 219


>UniRef50_A3EQA4 CRISPR-ssociated protein, Cas5 n=3 Tax=Bacteria RepID=A3EQA4_9BACT
          Length = 227

 Score =  163 bits (412), Expect = 4e-39,   Method: Composition-based stats.
 Identities = 59/227 (25%), Positives = 96/227 (42%), Gaps = 22/227 (9%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L++RL  PMQ+WG  +    R TG+ P++SG++GLL A LGI R++   L+ L+  +
Sbjct: 1   MPTLLIRLVSPMQSWGTSSRFDQRDTGKEPSKSGVIGLLAAALGIDRNNWDDLEPLA-GL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
              VR D              RDY T           K H T  T+REYL DA F V   
Sbjct: 60  SMGVRHDR--------PGIPRRDYQTASKIISA-DHSKIHPTAVTYREYLADAVFLVG-- 108

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGT-CQASDPQKALLNYEPVGGD 180
                  ++ ++  A+  P +  +LGR+S   + P+++    +    ++AL ++  +   
Sbjct: 109 FESAEVSLLEKINSALKNPVWPLFLGRKSYVPSEPIWIENGLKNVPLREALEHFPWIACR 168

Query: 181 IYSEESVT--------GHHLKFTARDEPM-ITLPRQFASREWYVIKG 218
             +E                     D+P+     R+F SR       
Sbjct: 169 RRNERLPEKLVITFESEDGTGVLKMDQPLSSFAKRRFGSRFVRSEWI 215


>UniRef50_A8M404 CRISPR-associated protein Cas5 family n=1 Tax=Salinispora arenicola
           CNS-205 RepID=A8M404_SALAI
          Length = 238

 Score =  163 bits (412), Expect = 5e-39,   Method: Composition-based stats.
 Identities = 65/235 (27%), Positives = 97/235 (41%), Gaps = 35/235 (14%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
            L+LRLAGP+Q+WG  +    R T   PT+SG++G+L A  G++R D   L  L  S+ F
Sbjct: 1   MLLLRLAGPLQSWGATSRFTHRHTQVTPTKSGVIGMLAAASGLRRTD--PLTELL-SLDF 57

Query: 64  AVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLT 123
            VR D+            LRD+                    T R YL DA F VA+   
Sbjct: 58  GVRIDQ--------PGQLLRDFQVARTLDGRDS------MPLTNRYYLSDAVFLVAI--- 100

Query: 124 PHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDIYS 183
                ++  L ++V +P +  YLGRR+CP   P+ LG        +AL ++         
Sbjct: 101 GGDQALLEGLHESVRRPHFPLYLGRRACPPVAPISLGVHPG-TVDEALRDWPWQAAKRLR 159

Query: 184 EE------------SVTGHHLKFTARDEPMITLP--RQFASREWYVIKGGMDVSQ 224
           E             +  G  +  T  D+P+   P  RQ+  R     +  +    
Sbjct: 160 ERGELTVPLEVVSDAPPGADVTETLPDQPISFDPAHRQYGWRAVVRTRIVVPNPD 214


>UniRef50_Q5YRB6 Putative uncharacterized protein n=1 Tax=Nocardia farcinica
           RepID=Q5YRB6_NOCFA
          Length = 235

 Score =  162 bits (409), Expect = 9e-39,   Method: Composition-based stats.
 Identities = 63/240 (26%), Positives = 101/240 (42%), Gaps = 36/240 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+LRLA P+Q+WG  +    R T ++P++SG+LGL+ A  G +R D   ++   +++
Sbjct: 1   MTVLLLRLAAPLQSWGVASRFARRETQQYPSKSGILGLIAAARGHRRTD--PIEEALQNL 58

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
            F VR D+            +RD+   L   +  +         + R YL DA F  A+ 
Sbjct: 59  AFGVRVDQ--------PGRLIRDFQVALNIDKTKQF------PLSQRYYLADAVFLAAI- 103

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                  +I  +  A+ +P +  YLGRRSCP+T PL LG  +    + AL   E      
Sbjct: 104 --QGERGLIEGIGNALRRPEFPLYLGRRSCPVTGPLVLGEPRDVTLEHALHETEWQAATW 161

Query: 182 YSEES---------------VTGHHLKFTARDEPMITLP--RQFASREWYVIKGGMDVSQ 224
           Y                        L+   RD P+   P  R++  R        M  ++
Sbjct: 162 YRRSQHRRVRLPIYRDLLPGDPVELLREQVRDMPLSFDPVRREYGWRTVVEDYTTMLNAE 221


>UniRef50_D0WFC8 CRISPR-associated protein Cas5 n=1 Tax=Slackia exigua ATCC 700122
           RepID=D0WFC8_9ACTN
          Length = 267

 Score =  159 bits (403), Expect = 5e-38,   Method: Composition-based stats.
 Identities = 60/250 (24%), Positives = 104/250 (41%), Gaps = 43/250 (17%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+L+LA P+Q+WG  +    R T   P++SG++GLL A LG +R+D  S+  L+ ++
Sbjct: 4   MTVLLLKLAAPLQSWGASSRFTERTTRHEPSKSGVIGLLAAALGRRRED--SVDDLA-AL 60

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHET---IQTWREYLCDASFTV 118
           +FAVR D+          + +RD+ T    + D    +         + R+YL DA   V
Sbjct: 61  RFAVRIDQ--------PGSFMRDFQTEHTRKWDSDTRRFVFNESLSLSKRDYLSDA---V 109

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVG 178
            +        +++E  +A+  P +  +LGRRSCP +  ++LG        +AL +     
Sbjct: 110 FVAALEGDEDLLAECAEALHHPAFPLFLGRRSCPPSTQVYLGLVDGP-MMEALADIPWQA 168

Query: 179 GDI-----YSEESVTGHHLKFTA------------------RDEPMITL--PRQFASREW 213
            +      Y                                RD P+      R++  R  
Sbjct: 169 TERHWNYAYRFRGDKPKETVELKVVYEATEEQAACTLSETVRDVPLSFSQLKREYGWRTE 228

Query: 214 YVIKGGMDVS 223
             I+  +  S
Sbjct: 229 TTIRMAVKNS 238


>UniRef50_Q1R114 CRISPR-associated protein, CT1976 n=1 Tax=Chromohalobacter
           salexigens DSM 3043 RepID=Q1R114_CHRSD
          Length = 260

 Score =  159 bits (403), Expect = 5e-38,   Method: Composition-based stats.
 Identities = 73/265 (27%), Positives = 108/265 (40%), Gaps = 52/265 (19%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M  +L+ RL  PM +WG+      RPT  +P R  +LGL+GA LGI+RDD      L +S
Sbjct: 1   MTGHLVFRLYAPMASWGEAAVGEARPTATYPGRGAILGLIGAALGIRRDDDEGQLRLRQS 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYR------------GLKSHETIQTWR 108
           +  AV+        +R     LRDYHTV       +               +  TI + R
Sbjct: 61  LGIAVK--------QRSPGWLLRDYHTVQVPPSQSKVNYRSRREELSVPKDALNTILSSR 112

Query: 109 EYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQ 168
           +Y CD  + VAL L P A   + EL+ A+ +PR+T YLGR++CPL  PL     +A   +
Sbjct: 113 DYRCDGLWVVALRLMPDAVWTLDELKSALERPRFTLYLGRKACPLAAPLTPAIVEADHWR 172

Query: 169 KAL---------LNYEPVG-----------------------GDIYSEESVTGHHLKFTA 196
            AL              +                        G+  + +           
Sbjct: 173 GALDHGFDSATDPERTWLPLIGNEAQDLRLLRLPGQVLYAWEGEADALDGNADMAESSET 232

Query: 197 RDEPMITLPRQFASREWYVIKGGMD 221
            DEP+     QF +R  +     ++
Sbjct: 233 WDEPLHRRRWQFGARLEHRRIESVE 257


>UniRef50_A6W168 CRISPR-associated protein Cas5 family n=6 Tax=Gammaproteobacteria
           RepID=A6W168_MARMS
          Length = 258

 Score =  159 bits (401), Expect = 9e-38,   Method: Composition-based stats.
 Identities = 78/253 (30%), Positives = 109/253 (43%), Gaps = 43/253 (16%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M+ YL+ RL GPM +WGQP   G R T   PTRS +LGLLGA LGI+RDD   L AL  S
Sbjct: 1   MKDYLVFRLYGPMASWGQPAVGGDRATAIAPTRSAILGLLGAALGIKRDDAQQLDALHSS 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRG-------------LKSHETIQTW 107
           VQ A +        +    + LRDYHT      + +               +   TI + 
Sbjct: 61  VQMATK--------QVTPTSLLRDYHTSQVPSRNNKYVYRTRKNELLDEHKEKLNTILST 112

Query: 108 REYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDP 167
           R+Y CD  + VA+ LT  +   +  L++A++KP Y   LGR+SCPL  PL      +   
Sbjct: 113 RDYRCDGIWIVAVSLTQESLFSLERLKQALIKPVYVLSLGRKSCPLAAPLLPVLLTSVSL 172

Query: 168 QKALL---------NYEPVGGDIYS-------------EESVTGHHLKFTARDEPMITLP 205
           ++AL          +   +                   +E      L     D+P+    
Sbjct: 173 REALDYPFPSIIDNDKPHLDAVWLRPNKLSTYTWEGSVDEFSGETALTTHPWDDPINRDR 232

Query: 206 RQFASREWYVIKG 218
            QF  R  + I  
Sbjct: 233 WQFKQRTMHQITV 245


>UniRef50_A7BA63 Putative uncharacterized protein n=1 Tax=Actinomyces odontolyticus
           ATCC 17982 RepID=A7BA63_9ACTO
          Length = 242

 Score =  159 bits (401), Expect = 9e-38,   Method: Composition-based stats.
 Identities = 68/245 (27%), Positives = 103/245 (42%), Gaps = 44/245 (17%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M + L+LRLAGPMQ+WG  +    R T  FPT+S L+GLLGA  G +R D   ++ L+E 
Sbjct: 1   MSAVLVLRLAGPMQSWGADSRFTRRSTEAFPTKSALVGLLGAAQGRRRSD--PIEDLAE- 57

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           +  AVR D+            L D+HT                  + R Y  DA+F   +
Sbjct: 58  LSVAVRVDQ--------PGQLLHDFHTAHRG--------DTSMPLSHRFYRADAAFGAFI 101

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180
                   +I  L +A+++P +  YLGRRSCP T PL L   + S    A+     +   
Sbjct: 102 EGPDD---MIDALAQAIVRPVFPLYLGRRSCPPTLPLRLAVREGSAW-DAVRETPWMAST 157

Query: 181 IYSEESVTGHHLKF-------------------TARDEPMITL--PRQFASREWYVIKGG 219
            Y ++    H ++                    T +D P+      R++  R        
Sbjct: 158 YYQKKQRHDHFVRMRVVADLGIIPPEVEKVAQQTLQDMPISFDSENRKYTLRTVEETYID 217

Query: 220 MDVSQ 224
           ++  Q
Sbjct: 218 LENPQ 222


>UniRef50_B8HWH8 CRISPR-associated protein Cas5 family n=1 Tax=Cyanothece sp. PCC
           7425 RepID=B8HWH8_CYAP4
          Length = 216

 Score =  157 bits (397), Expect = 2e-37,   Method: Composition-based stats.
 Identities = 52/218 (23%), Positives = 88/218 (40%), Gaps = 22/218 (10%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L+LR+  PM +WG  +    R + R PT+S ++GLL A LG  R    ++  L+ ++
Sbjct: 1   MPTLLLRMRAPMMSWGDHSRFTIRDSRREPTKSAVIGLLCAALGRPR--WEAVADLT-AL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +  VR ++  L           DYHTV              T+ + R Y+ DA + V L 
Sbjct: 58  KMGVRINQEGLVQC--------DYHTVQD--SIKSSGSKGNTVISHRYYIADADYLVGLE 107

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
            +      +  L+ A+  P +  Y GR+S   + P+ L         +AL +   +   +
Sbjct: 108 GS--DRHFLESLDSALQSPIWQVYFGRKSFVPSCPVALHVSDQP-LAEALKHRITLSKTM 164

Query: 182 YSEES------VTGHHLKFTARDEPMITLPRQFASREW 213
             +        +         +D P+    R F SR  
Sbjct: 165 AHKLPNRLRCVLEVPDSLDVRQDVPLDWQKRHFGSRCV 202


>UniRef50_B0TDU1 Crispr-associated protein cas5 n=1 Tax=Heliobacterium modesticaldum
           Ice1 RepID=B0TDU1_HELMI
          Length = 230

 Score =  155 bits (393), Expect = 7e-37,   Method: Composition-based stats.
 Identities = 65/229 (28%), Positives = 101/229 (44%), Gaps = 23/229 (10%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
            L LRL GP+Q+WG  +    R +   PT+SG++GLLG  LG  R+D   L++L  +++ 
Sbjct: 5   ILALRLEGPLQSWGSRSRWDYRDSALEPTKSGIIGLLGCALGWSRND-KRLESLDAALRL 63

Query: 64  AVRCDELILDDRRVSVTGLRDYHTVLGAR-----EDYRGLKSHETIQTWREYLCDASFTV 118
            VR D+          T L D+HTV G       +  +      T+ + R YL +ASF  
Sbjct: 64  TVRIDK--------PGTPLIDFHTVQGYLLMAEGKQKKSGNDMYTVVSRRVYLQEASF-- 113

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQAS--DPQKALLNYEP 176
            L L       + + +KA+  P +  +LGR+SCP   PLF    +    D  +A+ +   
Sbjct: 114 -LALLTGEQGALHQCKKALNDPVWPVFLGRKSCPPARPLFDSFYEGDFRDVLEAMRSIPW 172

Query: 177 ----VGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMD 221
                 G I     +     +   +D   I   R +  R   V    +D
Sbjct: 173 SSAPAAGPIRLRYVMEDEGGREWRQDVLRINGARMYGRRRVSVGWVDLD 221


>UniRef50_Q1EQS9 CRISPR-associated protein n=3 Tax=Streptomyces RepID=Q1EQS9_STRKN
          Length = 280

 Score =  155 bits (392), Expect = 1e-36,   Method: Composition-based stats.
 Identities = 71/247 (28%), Positives = 110/247 (44%), Gaps = 39/247 (15%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           L+LRL+GP+Q+WG+ +    R T RFPTRSG++G+L A LG +R     +  L+  +   
Sbjct: 14  LLLRLSGPLQSWGERSHFNERDTARFPTRSGIIGMLAAALGRRRG--EPVDDLA-RLSLT 70

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAR---------EDYRGLKSHETIQTWREYLCDAS 115
           VR D             LRD HTV G           E  +   +  T+ T R YL DA+
Sbjct: 71  VRTDR--------PGILLRDLHTVGGGLPAKATVTTAEGKKRPGTTGTLLTHRTYLADAA 122

Query: 116 FTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQAS------DPQK 169
           FT+AL  TP    ++ +  +A+  P +  +LGRRSCP   PL LG  + +       P  
Sbjct: 123 FTIALTSTPDDRPLLDQAAQALNTPCWPLFLGRRSCPPEGPLLLGASEDALHHLVHLPLA 182

Query: 170 ALLNYEPVGGDIYSEESV-------------TGHHLKFTARDEPMITLPRQFASREWYVI 216
           A         +  ++  +              G H      D+P+   PR+ + R   + 
Sbjct: 183 AHPGRGQQDTEFLADRPLNRLPYGTATPVGADGTHPSGEVNDQPLSFDPRRRSYRARPLY 242

Query: 217 KGGMDVS 223
           +  + + 
Sbjct: 243 RRSLRLP 249


>UniRef50_C7LYW6 CRISPR-associated protein Cas5 family n=1 Tax=Acidimicrobium
           ferrooxidans DSM 10331 RepID=C7LYW6_ACIFD
          Length = 253

 Score =  154 bits (388), Expect = 3e-36,   Method: Composition-based stats.
 Identities = 72/247 (29%), Positives = 96/247 (38%), Gaps = 41/247 (16%)

Query: 2   RSYLILRLAGPMQAWGQPTF-EGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
            S L LRL GP+QAWG     +  R T RFPT+SG++GLL A LG  R   ++L  L  +
Sbjct: 1   MSVLALRLGGPLQAWGSSQRLDHYRRTERFPTKSGVIGLLAAALGRPRS--AALDDLG-A 57

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHE----------------TI 104
           ++FAVR D             LRD+HT+    +D +     E                T 
Sbjct: 58  LRFAVRIDR--------PGEVLRDFHTLSSLFDDKKRFAPGEGRLPTASGGYRSAATSTQ 109

Query: 105 QTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQA 164
            T R YL DA F   +         + EL+ A+  P +  YLGRRSCP   PL LG    
Sbjct: 110 VTERFYLADACF---VAGLEGDAAQLQELDDALRTPVFPLYLGRRSCPPDKPLRLGVYDG 166

Query: 165 SDPQKALLNYEPVGGDIYS-------EESVTGHHLKFTARDEPMITLP--RQFASREWYV 215
                 L +      D          E  V          D+     P  R +  R    
Sbjct: 167 -GLIDVLASIPWQANDPAQSATSIRCELVVENPAGDVELADQARSFDPLTRSYTRRRVSH 225

Query: 216 IKGGMDV 222
               + +
Sbjct: 226 HYVEVTI 232


>UniRef50_A5GBK2 CRISPR-associated protein Cas5 family n=2 Tax=Deltaproteobacteria
           RepID=A5GBK2_GEOUR
          Length = 231

 Score =  153 bits (387), Expect = 4e-36,   Method: Composition-based stats.
 Identities = 60/220 (27%), Positives = 99/220 (45%), Gaps = 9/220 (4%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQAL--SES 60
           S+L LRL GP+Q+WG  +    R TG  PT+S + G+  A LG  R      + L    +
Sbjct: 11  SFLALRLEGPLQSWGFDSQYNRRNTGLMPTKSAIAGMCCAALGFLRGCDKEQEFLVAFGA 70

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           V+            + + V  L+DYHTV   R    G  +++ + T R+YL DA+F V L
Sbjct: 71  VRMTAIAIPRNGAKKELPVRRLQDYHTVQNTRRA-SGAINNDCVLTHRQYLTDAAFGVLL 129

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180
                 + ++ ++  A+  P +  +LGR++C  T P+  G  +  D    LL  +     
Sbjct: 130 E---GDSTLLKQIAAALENPVWGVWLGRKTCIPTAPVLAGLRENRDEALKLLLKDKPLES 186

Query: 181 IYSEESVTG-HHLKFTARDEPMIT--LPRQFASREWYVIK 217
              +E V      + +  D P+      R F+ R    ++
Sbjct: 187 FARQEDVESFADGRDSLPDMPVSFATERRIFSPRRVRTLQ 226


>UniRef50_Q03C60 CRISPR-associated protein n=4 Tax=Lactobacillus RepID=Q03C60_LACC3
          Length = 236

 Score =  153 bits (387), Expect = 4e-36,   Method: Composition-based stats.
 Identities = 56/240 (23%), Positives = 90/240 (37%), Gaps = 37/240 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              + +RL  P+Q++G       R TG +P++S ++G+L A LG QRDD  ++ AL++ +
Sbjct: 1   MKTISIRLTSPLQSYGNEAQFARRTTGDYPSKSAIIGMLAAALGYQRDD-PAINALNDLL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
            FAVR D+            + ++ T           K      T+R+ L DA F VA+ 
Sbjct: 60  -FAVRVDQ--------PGQVMTEFQTAE--------WKPGTRKLTYRDLLQDAVFVVAI- 101

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                   +  L +A+  PR+  YLGRR+      L + T    DP   L          
Sbjct: 102 -GSEDEAWLDRLAEALRHPRFQLYLGRRANVPAGVLKIQTFAGQDPVGVLAQLPWQASRW 160

Query: 182 YSEE----------------SVTGHHLKFTARDE-PMITLPRQFASREWYVIKGGMDVSQ 224
           Y                    +                   RQ++ R   V K  +   +
Sbjct: 161 YQRRSRRQASMSVQLIADAVLLPERRADLVRDAVHSFDQKHRQYSFRPIAVTKVQLANPE 220


>UniRef50_A8SDR7 Putative uncharacterized protein n=1 Tax=Faecalibacterium
           prausnitzii M21/2 RepID=A8SDR7_9FIRM
          Length = 220

 Score =  153 bits (386), Expect = 5e-36,   Method: Composition-based stats.
 Identities = 77/227 (33%), Positives = 108/227 (47%), Gaps = 24/227 (10%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+LRLA P+QAWG  +   TR TGR PT+SG++GLL A LG++RD++ +L  L+  +
Sbjct: 1   MATLLLRLAAPLQAWGADSKFETRKTGREPTKSGVIGLLAAALGLRRDESEALTRLT-GL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +F VR +             L DYHT     E            T+R YL DA F   + 
Sbjct: 60  RFGVRVER--------EGQLLVDYHTAKTQDEKTSY-------VTYRHYLQDAVFLAGIE 104

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
            T   T ++ +L++A+L P +  YLGRR CP T PL LG C     Q+ L    P+    
Sbjct: 105 ST--DTALLQQLQQALLHPAFPLYLGRRCCPPTLPLCLGVCPG-SLQEVLQAEPPLCPGR 161

Query: 182 YSEESVTG---HHLKFTARDEPMITLP--RQFASREWYVIKGGMDVS 223
            S   +            RD P+   P  RQ+  R    +   M  S
Sbjct: 162 QSRILLDADPLEPGTAPQRDVPVSFDPHHRQYGYRSVRELWQKMPDS 208


>UniRef50_Q0W584 Putative uncharacterized protein n=1 Tax=uncultured methanogenic
           archaeon RC-I RepID=Q0W584_UNCMA
          Length = 227

 Score =  152 bits (385), Expect = 6e-36,   Method: Composition-based stats.
 Identities = 60/218 (27%), Positives = 89/218 (40%), Gaps = 20/218 (9%)

Query: 10  AGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDE 69
            GPMQ+WG       R TG  PT+SG++GLLG  LG  R D      L   ++  +R + 
Sbjct: 12  EGPMQSWGLKARWDIRDTGDEPTKSGIIGLLGCALGYARKDPRLTDELDSQLRIGIRVEC 71

Query: 70  LILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPHATMV 129
                        RDYHTV G      G     TI ++R+YL DA+F V L        +
Sbjct: 72  --------PGEIARDYHTVSGELRTAEGKLRETTIVSFRDYLQDAAFLVVLEGPG---EL 120

Query: 130 ISELEKAVLKPRYTPYLGRRSCPLTHPLFLGT-CQASDPQKALLNYEPVGGDIYSEE--- 185
           ++ +  A+  P +  YLGR+SCP T P+F       +    AL  +    G + + +   
Sbjct: 121 LTRISNALKDPVWPIYLGRKSCPPTRPVFETLTTDYASIDDALSRHPWSSGTMEARKAHP 180

Query: 186 -----SVTGHHLKFTARDEPMITLPRQFASREWYVIKG 218
                 V      +   D    +  R +  R   +   
Sbjct: 181 KELKCIVEDLSGPYQRTDRMTKSPARMYGIRHVRMSTV 218


>UniRef50_B1VIY0 CRISPR-associated protein n=9 Tax=Actinomycetales
           RepID=B1VIY0_CORU7
          Length = 240

 Score =  152 bits (384), Expect = 9e-36,   Method: Composition-based stats.
 Identities = 60/240 (25%), Positives = 100/240 (41%), Gaps = 34/240 (14%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M   L+L L GPMQ+WG  +    R T   PT+SG++GL+ A  G +R D   ++ L++ 
Sbjct: 1   MAHSLLLLLKGPMQSWGDESRFSVRATATTPTKSGIVGLIAAAQGRRRTD--GVEDLAK- 57

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           ++ AVR D+          + LRDY T       +            R +L DA+F  A+
Sbjct: 58  LRMAVRVDQS--------GSLLRDYQTAQ----PWLKNPGANASLVTRYFLSDAAFVAAV 105

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180
                   ++ ++ +A+ +P Y  Y+GRRSCP+   L +G       + AL  ++     
Sbjct: 106 E--SEDRELLDQMAEALRRPAYPLYMGRRSCPVHPGLVIGVVDGD-AESALRAHDTWHAT 162

Query: 181 IYSEESV-------------TGHHLKFTARDEPMITLP--RQFASREWYVIKGG-MDVSQ 224
               +                G       +D P+   P  R++  RE    +   +D   
Sbjct: 163 AVHRKESPKKVSLAIYRDANPGEGGSVPRQDVPVSFSPEHRKYGWREVIRAEDVEIDNPD 222


>UniRef50_C8XAY4 CRISPR-associated protein Cas5 family n=2 Tax=Actinomycetales
           RepID=C8XAY4_NAKMY
          Length = 252

 Score =  152 bits (383), Expect = 1e-35,   Method: Composition-based stats.
 Identities = 64/250 (25%), Positives = 95/250 (38%), Gaps = 47/250 (18%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            S L+LRL GPMQ+WG+ +    R T   P++S ++GLL A LG +R D  +++ L+  +
Sbjct: 1   MSVLVLRLTGPMQSWGERSRYARRETAAEPSKSAIVGLLAAALGRRRTD--AIEDLA-GL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
            F VR D+          T LRD+ T                  + R YL DA F  A+ 
Sbjct: 58  IFGVRVDQ--------PGTLLRDFQTARSLDGART------MPLSERYYLSDARFLAAVE 103

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTC-QASDPQKALLNYEPVGGD 180
                  +I+ L  A+  P +  YLGRRSCP + P+    C ++     AL +       
Sbjct: 104 ---GPESLIAGLAGALRDPTFPLYLGRRSCPPSEPIAQQDCIRSGPLLAALFDEPWHATK 160

Query: 181 IYSEESVT------------------------GHHLKFTARDEPMITLP--RQFASREWY 214
            Y                                 +    RD P+   P  R +  R   
Sbjct: 161 SYRRRVADPARLSIAVDAAATEVPAQLAERLTDPEVPQLVRDHPVSFDPRARTYGLRSVI 220

Query: 215 VIKGGMDVSQ 224
                +D   
Sbjct: 221 RGAVVVDNPD 230


>UniRef50_Q04QB7 Putative uncharacterized protein n=2 Tax=Leptospira borgpetersenii
           serovar Hardjo-bovis RepID=Q04QB7_LEPBJ
          Length = 247

 Score =  151 bits (382), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 65/248 (26%), Positives = 96/248 (38%), Gaps = 42/248 (16%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M+ YL+ RL GP+ +WG       RP+  FPT+S ++GL+ A  G  R +   +  L +S
Sbjct: 1   MKDYLVFRLYGPLVSWGNIAVGEYRPSDSFPTKSAIIGLISASFGFDRSEDGKISELVKS 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRG----------LKSHETIQTWREY 110
           V FA +               LRDYHT+       R            +  ETI + R+Y
Sbjct: 61  VFFATKTLN--------PGNLLRDYHTIQSPGNVKRSLLTRKDELLDSEYVETILSSRDY 112

Query: 111 LCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKA 170
             DA + VAL     A   + E+  A+L P +TPYLGR+SC +  P+      +     A
Sbjct: 113 RVDAVYDVALSEKKRAPYSLKEIRNALLSPIHTPYLGRKSCSIALPMCPEILSSDSFPNA 172

Query: 171 LLNYEPVGGDIYSEESVTGHHLKF------------------------TARDEPMITLPR 206
              Y  +    Y                                    + RDE +     
Sbjct: 173 FEEYNKILMKKYESSDYKDPLADLSSKSSAILYLWEDPTELSEKDHTHSRRDEILNRNKW 232

Query: 207 QFASREWY 214
           QF  R+ +
Sbjct: 233 QFQDRKEF 240


>UniRef50_D0Y918 CRISPR-associated protein Cas5 family n=2 Tax=Dehalococcoides
           RepID=D0Y918_9CHLR
          Length = 205

 Score =  151 bits (381), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 63/215 (29%), Positives = 100/215 (46%), Gaps = 17/215 (7%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
            L++RL GPMQ+WG  +    R T   PTRSG++GL+ A +GI RD+     A  + ++ 
Sbjct: 6   TLLMRLEGPMQSWGYRSRFDCRDTALEPTRSGVIGLICAAMGIARDED---IARFDGIRM 62

Query: 64  AVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLT 123
            VR D     ++        DYHT L            +T+ ++R+YL DASFTV L  +
Sbjct: 63  GVRVDRDGKVEQ--------DYHTALDV--IKADGSGKDTVVSYRDYLTDASFTVGLESS 112

Query: 124 PHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDIYS 183
                ++ ++ KA++ P++  +LGR++ PLT P          P    L    + G    
Sbjct: 113 --DRNLLEKIAKALVSPQWVLFLGRKAFPLTKPPIFEFSNPVKPGS--LEEHLLCGASAK 168

Query: 184 EESVTGHHLKFTARDEPMITLPRQFASREWYVIKG 218
              +     + T  D P+    R+F  R + V   
Sbjct: 169 RVLLESPDGERTQYDWPLCFGERRFKPRRFTVKYV 203


>UniRef50_C2BET8 CRISPR-associated protein n=2 Tax=Firmicutes RepID=C2BET8_9FIRM
          Length = 244

 Score =  150 bits (380), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 63/236 (26%), Positives = 102/236 (43%), Gaps = 29/236 (12%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
             ++L+L GPMQ+WG  +   TR +  +P++SG++G++ A  G +RD+   +Q L++ + 
Sbjct: 5   KTILLKLTGPMQSWGTSSRFETRTSDYYPSKSGVIGIIAASFGYERDEDEKIQKLND-LD 63

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWL 122
           FAVR D+             +DYH     R+     +   T  T R Y+ DA F VA+  
Sbjct: 64  FAVRVDQ--------EGVLKKDYHIA---RKVKPNGELERTYVTNRYYMEDAVFVVAIS- 111

Query: 123 TPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDIY 182
                  + E+ + +  P + P++GRRSCPL     LGT +   P +AL N +    D +
Sbjct: 112 -HEDDKWMEEILQGLKYPYFQPFMGRRSCPLPARFILGTNE-EGPIEALENLDWQAADWF 169

Query: 183 SEE--------------SVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVSQ 224
            ++                   H     R        R+F  R        M  S 
Sbjct: 170 KKKNKNYRADIYADKDLLPENSHTIRNDRVVSFSQKERKFGPRFEARSSLVMAKSD 225


>UniRef50_Q2JWC5 CRISPR-associated protein Cas5, Ecoli subtype n=1 Tax=Synechococcus
           sp. JA-3-3Ab RepID=Q2JWC5_SYNJA
          Length = 207

 Score =  150 bits (379), Expect = 3e-35,   Method: Composition-based stats.
 Identities = 50/228 (21%), Positives = 92/228 (40%), Gaps = 33/228 (14%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L++RL  PM +WG  +    R + R PT+S ++G+L A LG  R     +  L+ ++
Sbjct: 1   MTTLLMRLRAPMMSWGDHSQFDYRDSRREPTKSAVIGILCAALGRPR--WEPVDDLA-AL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +  VR ++             +D+HTV                 + R Y+ D  + V L 
Sbjct: 58  KMGVRVNK--------EGILCKDFHTVQIKE-----------TISNRYYVADGDYLVGLE 98

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                  ++  L++A+ KP +  +LGR+S   + PL +G  +     +AL  +       
Sbjct: 99  ---GDPNLLRTLDQALQKPYWQVFLGRKSFIPSRPLRVGLVEQP-LLEALRQHPYECSRR 154

Query: 182 YSEES-----VTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVSQ 224
               S     +         +D P+   PR+F  R         ++ +
Sbjct: 155 GKRPSQLRFVLEVSESLDVRQDVPLSWQPRRFGCRAV--ETEYHELPE 200


>UniRef50_D1CAJ0 CRISPR-associated protein Cas5 family n=1 Tax=Sphaerobacter
           thermophilus DSM 20745 RepID=D1CAJ0_SPHTD
          Length = 245

 Score =  150 bits (378), Expect = 5e-35,   Method: Composition-based stats.
 Identities = 61/249 (24%), Positives = 91/249 (36%), Gaps = 42/249 (16%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            S L+LRL GPMQAWG  +    R TG  P++SG++GLL A LG  R   + +  L+  +
Sbjct: 1   MSTLLLRLTGPMQAWGTQSRFSWRDTGLEPSKSGVIGLLCAALGRPRS--APVDDLA-RL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDY--------RGLKSHETIQTWREYLCD 113
           +  VR D           T   D+HT  G                 +     + R YL D
Sbjct: 58  RMGVRVDR--------EGTMHVDFHTAGGWHRRAEAGYGVPDPSGTARRPQISRRFYLAD 109

Query: 114 ASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTH--------PLFLGTCQAS 165
           A F V L        ++  L++A+  PR+  +LGR+S             P   G     
Sbjct: 110 ADFLVGLE---GDEELLVLLDRALAAPRWQLFLGRKSFVPAAPVRLPDTPPWGPGLRPEP 166

Query: 166 DPQKALLNYEPV-----------GGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWY 214
             + AL  Y  +              +       G        D P+    R+F++R   
Sbjct: 167 -LETALRTYPWLGYQLPHPRADAPDRLRLVLDAEGDDAADIRMDVPISFAERRFSTRAVR 225

Query: 215 VIKGGMDVS 223
            +       
Sbjct: 226 TVWIATPPP 234


>UniRef50_UPI0001AF1D4C CRISPR-associated protein, CT1976 n=1 Tax=Streptomyces ghanaensis
           ATCC 14672 RepID=UPI0001AF1D4C
          Length = 244

 Score =  149 bits (377), Expect = 5e-35,   Method: Composition-based stats.
 Identities = 59/247 (23%), Positives = 89/247 (36%), Gaps = 41/247 (16%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L++    PMQ+WG  +   +R T   PT+SG++GLL A LGI RD    +Q L+E +
Sbjct: 1   MATLLMCFDAPMQSWGTRSQFASRDTATEPTKSGVVGLLAAALGIPRDADEEIQNLAE-L 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +  VR D               D+HTV          K+H T  T R YL DA F V + 
Sbjct: 60  RMGVRVDR--------EGVVEADFHTVQNVPNTE--GKNHRTAVTKRFYLADALFLVGVE 109

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPL-FLGT------CQASDPQKALLNY 174
                T ++ +L  A+  PR+  Y GR++     P+   G               AL  +
Sbjct: 110 --SDDTQLLHQLHTALTAPRWPLYFGRKAFVPARPIPSPGLAGEHHPVTGQSLDDALRTH 167

Query: 175 EPVGGD-----------------IYSEESVTGHHL--KFTARDEPMITLP--RQFASREW 213
             +                                       D P+      R +A R  
Sbjct: 168 PWLENQLRIHANRRTTAYAPSPAWLRTIVDADPLALDVELRHDHPLSFTQQDRSYAPRAV 227

Query: 214 YVIKGGM 220
            +    +
Sbjct: 228 QISHVPL 234


>UniRef50_C7MQD6 CRISPR-associated protein Cas5 n=1 Tax=Saccharomonospora viridis
           DSM 43017 RepID=C7MQD6_SACVD
          Length = 236

 Score =  149 bits (377), Expect = 6e-35,   Method: Composition-based stats.
 Identities = 67/234 (28%), Positives = 102/234 (43%), Gaps = 26/234 (11%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+L L GPMQAWG  +    R T  +PTRSG++G++ A LG Q  D  SL  LS  +
Sbjct: 1   MTTLVLHLDGPMQAWGHASQWDHRDTLDYPTRSGVIGMIAAALGKQWGD--SLDDLSP-L 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHET----IQTWREYLCDASFT 117
           +F +R D             + DYHT  G  E              + + R Y+ DA++T
Sbjct: 58  RFTIRIDR--------PGRRIVDYHTAGGGYEVGIARVKGGNRAHAVLSDRFYMSDAAYT 109

Query: 118 VALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQK-ALLNYEP 176
           VA+        ++  ++ A+  P + P+LGRRSCP   P  LG       +   L   +P
Sbjct: 110 VAITGPD---TLLYRVDDALRAPVFGPFLGRRSCPPAGPWHLGLHDGDPLRTLPLHRDKP 166

Query: 177 VGGDIYSEESVTGHHLKFTARDE------PMITLPRQ-FASREWYVIKGGMDVS 223
             GD  + E V+ H               P    PR+ + +   +     + V+
Sbjct: 167 RDGDTVAVEFVSDHETHGPTDRVDTTLTDPHEFGPRRSYGTVTTHRWTETLPVA 220


>UniRef50_D2L2X8 CRISPR-associated protein Cas5 family n=1 Tax=Desulfovibrio sp.
           FW1012B RepID=D2L2X8_9DELT
          Length = 266

 Score =  149 bits (375), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 70/249 (28%), Positives = 95/249 (38%), Gaps = 45/249 (18%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M  YLI +L G + A+G       R +   PTRS + GLL ACLGI+R + + L ALS  
Sbjct: 1   MARYLIFQLYGMLAAYGLVAVGEVRLSAGHPTRSAVFGLLAACLGIRRHEEARLAALSGG 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYR---------------GLKSHETIQ 105
              AVR D           T L DYHT+    E  +                 +   T+ 
Sbjct: 61  YALAVRVD--------APGTSLLDYHTIQTPPEKSKRIYRTRADELGGLLGIDEPPYTVL 112

Query: 106 TWREYLCDASFTVALW------LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFL 159
           + R YLCDA FT  L               +  L +A+ +P  TPYLGR+SCP + P   
Sbjct: 113 SRRGYLCDAHFTACLTPAAAPPTDATPPHTLEALAEALRRPVLTPYLGRKSCPPSLPFHP 172

Query: 160 GTCQASDPQKALLNYE----------------PVGGDIYSEESVTGHHLKFTARDEPMIT 203
              +    + AL +Y                  V  D     +      +   RD  +  
Sbjct: 173 RLGEYDSLEAALADYPLEKLAFPAGLKPHDPAVVFADEDEAITPATVTSRPLVRDRTVQH 232

Query: 204 LPRQFASRE 212
             R F  R 
Sbjct: 233 GRRLFEERR 241


>UniRef50_B4S8P8 CRISPR-associated protein Cas5 family n=8 Tax=Bacteria
           RepID=B4S8P8_PROA2
          Length = 243

 Score =  148 bits (374), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 55/243 (22%), Positives = 89/243 (36%), Gaps = 28/243 (11%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
           YL+L L  P+Q+WG  +  G R T  FPT+SG+LG+L   LG   +    L+ ++   Q 
Sbjct: 5   YLLLWLEAPLQSWGADSRFGRRGTLEFPTKSGVLGMLCCSLGAGGEQKELLEKMAPLKQS 64

Query: 64  AVRCDELILDDRRV-----SVTGLRDYHTVLGAREDYRGLK--------------SHETI 104
           A+         +           LRD+H V    +D    +              +  + 
Sbjct: 65  AISFCRTSKFRQEEIKKLDREPLLRDFHMVGSGYDDKNPWETLLIPKKSDGTTAVNGGSK 124

Query: 105 QTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQA 164
            T+R YL DA F V + +      +      A+  P +  Y GR+ C  T  ++ G    
Sbjct: 125 ITYRYYLQDAVFAVIMEVPSEKLTLF---ADALENPCWDIYFGRKCCAPTDFIYRGCFNT 181

Query: 165 SDP--QKALL--NYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQ-FASREWYVIKGG 219
                 KAL     + +  D                 D P+    ++ +  R   VI   
Sbjct: 182 ESLAIGKALEIAQEKRLMEDF-RVVDGEHEGEAIVLNDVPIQFGEQKLYRERRVTVISCA 240

Query: 220 MDV 222
            + 
Sbjct: 241 NEN 243


>UniRef50_A1SV73 CRISPR-associated protein, Cas5e family n=2 Tax=Gammaproteobacteria
           RepID=A1SV73_PSYIN
          Length = 217

 Score =  148 bits (373), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 78/214 (36%), Positives = 110/214 (51%), Gaps = 15/214 (7%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              LIL+  G M A+G  TF+  R    FPTRS ++G+LGA +GI R++ + L ALSE +
Sbjct: 1   MKTLILKTEG-MSAYGLQTFDVHRRANHFPTRSAIMGILGAAMGITRENFNELYALSEQL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           + AV+          +S   + DYHTV   R   +G        T+REY CD+  T A+ 
Sbjct: 60  KIAVQV--------NLSGEKMVDYHTVQHFRSP-QGKIQKGVKPTYREYWCDSEHTFAIS 110

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
               A  VI +L  +V  P +T + GR+SCPLT PLF       +P  AL N+    G I
Sbjct: 111 A---AEHVIEKLVNSVKFPEFTLFQGRKSCPLTRPLFEAVTDDDNPANALKNHGEQ-GQI 166

Query: 182 YSEESVTGHHLKFTARDEPMITLPRQFASREWYV 215
           +S+ S          RD  +  +PR++A R  YV
Sbjct: 167 FSDISGDNQLAIVQVRDL-ITAIPRKYAMRTVYV 199


>UniRef50_Q2RY19 CRISPR-associated protein, Cas5e family n=1 Tax=Rhodospirillum
           rubrum ATCC 11170 RepID=Q2RY19_RHORT
          Length = 261

 Score =  148 bits (373), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 69/214 (32%), Positives = 93/214 (43%), Gaps = 21/214 (9%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
            +L+ RL GPM AWG       R T   P +S +LGLL A LGI R D ++ +AL   + 
Sbjct: 5   DFLVFRLVGPMAAWGDIAVGERRGTWDVPAKSAILGLLAAGLGIDRADRTAHEALDRGLG 64

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGA----------REDYRGLKSHETIQTWREYLC 112
           FAVR D             LRDYHT              R D        T+ + R Y  
Sbjct: 65  FAVRQDR--------PGRLLRDYHTAQAPKARKNARWSTRRDELNDDDLNTVLSDRLYRT 116

Query: 113 DASFTVALWLTPHAT-MVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKAL 171
           +A  T A+W         + +L +A+L+PR+TPYLGR++CPL  P      QA     A 
Sbjct: 117 NAIATPAIWRRQGTEGPTLDQLTQALLRPRFTPYLGRKACPLGWPPRPRLLQADGLLAAF 176

Query: 172 LNYEPVGGDIYS--EESVTGHHLKFTARDEPMIT 203
             Y+    D      ++  G     T R  P+  
Sbjct: 177 DAYDSAEWDAARQFHKAYPGGWPGDTDRPTPVWF 210


>UniRef50_D2RB02 CRISPR system CASCADE complex protein CasD n=3 Tax=Actinobacteria
           (class) RepID=D2RB02_GARVA
          Length = 291

 Score =  147 bits (370), Expect = 4e-34,   Method: Composition-based stats.
 Identities = 53/187 (28%), Positives = 87/187 (46%), Gaps = 17/187 (9%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQR--DDTSSLQALSE 59
              L+L+ +GP+Q+WG  +   TR T  +P++S ++G++ A  G +R  D   ++  L++
Sbjct: 1   MKSLLLKFSGPLQSWGTDSHFETRHTDYYPSKSAVIGMIAAAFGYRRSTDCDENIAKLND 60

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
            + FAVR D+            LRDYH      +        +   T R YL DA F VA
Sbjct: 61  -LDFAVRIDQ--------QGNLLRDYHIA---AKYKANGDFEKNYVTNRYYLEDAIFLVA 108

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGG 179
           +    +   +I ++  A+  P +   LGRRS P T    LG  +     +ALL +E +  
Sbjct: 109 I--GSNNEQLIYDISNALRSPYFQSSLGRRSLPPTADFILGV-EDCGVIQALLTHEWLAN 165

Query: 180 DIYSEES 186
               +  
Sbjct: 166 KWSKKRF 172


>UniRef50_B2GBJ9 Putative uncharacterized protein n=1 Tax=Lactobacillus fermentum
           IFO 3956 RepID=B2GBJ9_LACF3
          Length = 235

 Score =  146 bits (369), Expect = 4e-34,   Method: Composition-based stats.
 Identities = 57/240 (23%), Positives = 87/240 (36%), Gaps = 39/240 (16%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQR--DDTSSLQALSE 59
              L++R+A P+Q++G P     R T R P++S ++G++GA LG +R  DD  SL  L  
Sbjct: 1   MKTLVIRIAAPLQSYGDPASFEKRTTFRAPSKSAVIGMIGAALGFRRESDDYKSLNDLD- 59

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
              FAVR D+            L D+                    + R YL DA F VA
Sbjct: 60  ---FAVRVDQ--------PGEVLSDFQITH-------YSLKKPGKLSHRIYLQDAVFMVA 101

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGG 179
           L     A  ++ E+E A+  P++  Y GRRS P    L +  C        L        
Sbjct: 102 LSSKQDA--LMEEIEYALRHPKFQLYFGRRSNPPAGILKMKMCPDKTAINVLKELPWQAS 159

Query: 180 DIYSEESVTGHHLKFTARDEPMITLP----------------RQFASREWYVIKGGMDVS 223
             +  +            D  ++                   R +  R        ++ S
Sbjct: 160 VWFQRKYKKDVFNARIYADAKLVPDRPNRLIKDAVGSFNQKSRYYEYRSVAEDNVFLENS 219


>UniRef50_C5SD48 CRISPR-associated protein Cas5 family n=1 Tax=Allochromatium
           vinosum DSM 180 RepID=C5SD48_CHRVI
          Length = 227

 Score =  146 bits (369), Expect = 5e-34,   Method: Composition-based stats.
 Identities = 107/225 (47%), Positives = 134/225 (59%), Gaps = 9/225 (4%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M SYLILRL GPMQAWG  TFE  RP+  FPTRSGLLGLLGACLG+ R DT SL AL+ES
Sbjct: 1   MPSYLILRLDGPMQAWGTHTFEDYRPSNPFPTRSGLLGLLGACLGLDRSDTPSLDALAES 60

Query: 61  VQFAVRCDE-----LILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDAS 115
           V F VR D       +        T L DYHTVL AR+   G  +   IQ+ REYL DA+
Sbjct: 61  VAFTVRLDTGAPRPGVDRLMPKRHTKLSDYHTVLDARKV-DGSTNKFPIQSHREYLFDAA 119

Query: 116 FTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPL--FLGTCQASDPQKALLN 173
           F VA+   P A+  ++ + +++ +PR+TP LGRRSCPL  PL       +A D + AL  
Sbjct: 120 FAVAIGSRPDASFSLARIAESLRQPRFTPVLGRRSCPLGRPLLERPDCIEADDAKAALAQ 179

Query: 174 YEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKG 218
           + P GG IYSE+ +      +   D P     RQFA+R  Y+ + 
Sbjct: 180 FPPHGGLIYSEDELVSDQPTWIR-DVPRYGRHRQFATRRLYLHRE 223


>UniRef50_A8LYZ7 CRISPR-associated protein Cas5 family n=2 Tax=Actinomycetales
           RepID=A8LYZ7_SALAI
          Length = 257

 Score =  146 bits (368), Expect = 5e-34,   Method: Composition-based stats.
 Identities = 76/244 (31%), Positives = 104/244 (42%), Gaps = 43/244 (17%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+LRLAGPMQ+WG  +    R TG  PTRS ++G++ A  G  R     L  L+  V
Sbjct: 1   MTGLLLRLAGPMQSWGDHSTFSVRDTGTVPTRSAMIGIIAAAQGRHRG--EPLGDLAP-V 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGA---------REDYRGLKSHETIQTWREYLC 112
           QF VR D           T + D+HTV G           E  R      TI + R YL 
Sbjct: 58  QFTVRVDR--------PGTVMSDFHTVGGGAPPERTVPTAEGKRRTAGAGTIVSRRFYLA 109

Query: 113 DASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKAL- 171
           DA FTVA+        ++ ++  A+  P + PYLGRRSCP+ HP  +      DP   L 
Sbjct: 110 DAVFTVAVTGPDD---LVGQIHTALNNPVWGPYLGRRSCPVAHPFLMS-GPIPDPVGRLE 165

Query: 172 -----LNYEPVGGDIYSEESV------TGHHLKFTARDEPM-------ITLPRQFASREW 213
                    P   +    + V       G   + T  D PM           R++ +R+ 
Sbjct: 166 HLPLNRRRPPGDEETVRVDFVTGAPHGDGSISRMTLNDVPMEPVPGSPDPRRRRYLTRQV 225

Query: 214 YVIK 217
           YV  
Sbjct: 226 YVTT 229


>UniRef50_B8GIV3 CRISPR-associated protein Cas5 family n=1 Tax=Methanosphaerula
           palustris E1-9c RepID=B8GIV3_METPE
          Length = 257

 Score =  145 bits (367), Expect = 7e-34,   Method: Composition-based stats.
 Identities = 69/245 (28%), Positives = 95/245 (38%), Gaps = 37/245 (15%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
            YL   L G M +WG       RPT   PTRS +LGLL A LGI+RD+   L AL+ + +
Sbjct: 5   EYLTFSLYGMMASWGDIAVGEYRPTADHPTRSAVLGLLAAALGIRRDEEERLAALTRAYK 64

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKS-------------HETIQTWRE 109
            A+R D             LRDYHT        +G +                TI + R+
Sbjct: 65  VAIRVD--------APGMLLRDYHTTQVPSAAKKGRQYLTRKDELAAPREVLNTILSTRD 116

Query: 110 YLCDASFTVALWLTPHATMV-ISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQ 168
           Y CDA + V +W    A    +  L + +  P +T YLGR+SCPL  P+      A D  
Sbjct: 117 YRCDAVYRVYIWCRDTAPPYSLKTLAEHLQHPVFTLYLGRKSCPLALPVNPEVKTAPDLL 176

Query: 169 KALLNYEPVGGDIY------SEESVTGHH---------LKFTARDEPMITLPRQFASREW 213
            AL     +            + +V  +                DE +     QF  R+ 
Sbjct: 177 TALSEEREIELRFLGRVPGNRDSNVRAYWDCTEGIQAEGTSVRNDESLNRRRWQFGRRDE 236

Query: 214 YVIKG 218
                
Sbjct: 237 EYAMI 241


>UniRef50_C9M2Y8 CRISPR-associated protein n=1 Tax=Lactobacillus helveticus DSM
           20075 RepID=C9M2Y8_LACHE
          Length = 241

 Score =  145 bits (366), Expect = 9e-34,   Method: Composition-based stats.
 Identities = 50/200 (25%), Positives = 85/200 (42%), Gaps = 16/200 (8%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
                +RL  P+Q++G       R +  +P++S ++G++ A LG +RDD   LQ    ++
Sbjct: 1   MKTATIRLTAPLQSYGNQASFNQRTSDNYPSKSAVIGIIAAALGYRRDDARILQ--LNNL 58

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
            FAVR ++            + ++ TV    E  +         T+RE++ DA F VA+ 
Sbjct: 59  LFAVRIEQS--------GNMMTEFQTV----EYQKSSTKTARKLTYREFIQDAVFMVAI- 105

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
                   I ++  A+  P++  YLGRRS P   PL + T    +P + L          
Sbjct: 106 -GSDNDHEIEKIVSALKHPKFQLYLGRRSNPPAGPLMIETYDEENPLQVLEKLSWQAEPW 164

Query: 182 YSEESVTGHHLKFTARDEPM 201
           Y +       L     D  +
Sbjct: 165 YQKRLRAPKFLTRIIADAEL 184


>UniRef50_A8ZZ17 CRISPR-associated protein Cas5 family n=1 Tax=Desulfococcus
           oleovorans Hxd3 RepID=A8ZZ17_DESOH
          Length = 259

 Score =  145 bits (365), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 65/262 (24%), Positives = 96/262 (36%), Gaps = 54/262 (20%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             YL+ RL GPM +WG+     TR T  +P RS ++GL+ A LGI+R +T + QAL +  
Sbjct: 1   MGYLLFRLYGPMASWGEIAVGETRHTANYPGRSAIIGLMAAALGIKRSETENQQALDQGC 60

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAR------------EDYRGLKSHETIQTWRE 109
             AV              + LRDYHT                 E   G     TI + RE
Sbjct: 61  LIAVEARSH--------GSLLRDYHTTQVPDSVGGFVYRTRRDELIIGKPRLGTILSSRE 112

Query: 110 YLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGT-CQASDPQ 168
           Y  DA    A+ + P A   +  ++  + +PR   YLGR+SCPL+ P+       + +  
Sbjct: 113 YRQDALAVSAVRVLPGARYELQTIKTHLEQPRLHVYLGRKSCPLSAPMNPQIDKTSRNFH 172

Query: 169 KALLNYEPVGGDIYSEESVTG---------------------------------HHLKFT 195
           +A   Y              G                                       
Sbjct: 173 EAFQAYAHQPLLPVHHSGKEGLSKRDAYWLGLANDRHYYWEGEPSEFSDTIDLSRVQTRI 232

Query: 196 ARDEPMITLPRQFASREWYVIK 217
             D+P+     QF+ R+ +   
Sbjct: 233 RHDQPLSRTRWQFSPRQEHYWY 254


>UniRef50_A5UR14 CRISPR-associated protein, Cas5e family n=1 Tax=Roseiflexus sp.
           RS-1 RepID=A5UR14_ROSS1
          Length = 262

 Score =  144 bits (364), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 74/263 (28%), Positives = 103/263 (39%), Gaps = 55/263 (20%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L LRL GP+Q+WG     G R T   PT+SG++GLLG  LG++RDD + L+ LS+++
Sbjct: 1   MNTLFLRLEGPLQSWGLRARWGERDTTDAPTKSGVIGLLGCALGLRRDD-ARLRDLSDNL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSH-------------------- 101
           +  VR D        +    +RDYHT  G R                             
Sbjct: 60  RMGVRVD--------LPGILMRDYHTTGGGRYSTIASTGGPRYHDEPYIGGVLSAEVTKG 111

Query: 102 -------------ETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGR 148
                        ET  + R YL DASF VAL  +P     I EL  A+  P +  +LGR
Sbjct: 112 RIKVKINQKTGEPETDVSERYYLADASFLVALQGSPD---YIGELATAIQSPVWPLFLGR 168

Query: 149 RSCPLTHPLFLGTCQASDPQKALLN---YEPVGGDIYSEESVT-------GHHLKFTARD 198
           ++C  + P+F GT Q    + AL N      V                  G        D
Sbjct: 169 KACVPSTPIFAGTGQFDILEDALKNLLLSPRVETAWQRSRPTQLRLLIETGPGAGNRQYD 228

Query: 199 EPMITLPRQFASREWYVIKGGMD 221
                  R F +R        ++
Sbjct: 229 NIGTPSRRVFRARYVRETWLRLE 251


>UniRef50_D1A6Q5 CRISPR-associated protein Cas5 family n=2 Tax=Actinomycetales
           RepID=D1A6Q5_THECD
          Length = 273

 Score =  144 bits (363), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 72/243 (29%), Positives = 106/243 (43%), Gaps = 44/243 (18%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           L+L L+GP+Q+WG+ +    R T   PTRSGL+G++ A  G +R     +  L  +++F 
Sbjct: 9   LLLHLSGPLQSWGERSRFNQRDTATAPTRSGLIGMIAAAFGRRRT--EPVTDLR-ALRFT 65

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGA---------REDYRGLKSHETIQTWREYLCDAS 115
           VR D           T LRD+HTV G           E  R      T+ + R YL DA+
Sbjct: 66  VRIDR--------PGTLLRDFHTVGGGMPRDLTVITAEGKRRAADTATVTSDRYYLQDAA 117

Query: 116 FTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYE 175
           FTVA+        ++    +A+  PR+  YLGRRSCP   PL L   + +DP  AL++  
Sbjct: 118 FTVAVTA--DDPALLDRCAQALRAPRWPLYLGRRSCPPNAPLLLTVLR-TDPVTALIDLP 174

Query: 176 -------------------PVGGDIYSEESVTGHHLKFTARDEPMITLP--RQFASREWY 214
                                        +     +   A+DEP+   P  R+F +R  Y
Sbjct: 175 LARTAPRDRGDVLVEFRSDTPFESRAWPSAPEDEQVYTEAQDEPVSFQPHHRRFQTRPIY 234

Query: 215 VIK 217
              
Sbjct: 235 RRH 237


>UniRef50_C7MTB0 CRISPR-associated protein Cas5 n=1 Tax=Saccharomonospora viridis
           DSM 43017 RepID=C7MTB0_SACVD
          Length = 255

 Score =  144 bits (362), Expect = 3e-33,   Method: Composition-based stats.
 Identities = 75/241 (31%), Positives = 103/241 (42%), Gaps = 36/241 (14%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            S L+LRLAGP+Q+WG+ +    R T  FPT SGLLGLL   +G +R    SL+ L+ ++
Sbjct: 1   MSGLLLRLAGPLQSWGERSTFDVRDTAGFPTHSGLLGLLACVMGRRRG--ESLEDLA-AL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGARE---------DYRGLKSHETIQTWREYLC 112
            F +R D           T + DY T  GA                    T+QTWREYL 
Sbjct: 58  TFTIRVDR--------PGTRIIDYQTAGGALPPSMKVPTADGKGRPAGKGTVQTWREYLA 109

Query: 113 DASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALL 172
           DA F VA+        V+ ++  A+  P + PYLGRRSCP   PL L      DP   L 
Sbjct: 110 DAVFVVAVQGPS---EVLDQVRHALRYPHWQPYLGRRSCPPDQPLLLDV-PVEDPVAELC 165

Query: 173 NYEPVGGDIYSEESVTGHHLKFTAR----------DEPMITL--PRQFASREWYVIKGGM 220
              P+   +  +E        F             D P+      R ++ R  +     +
Sbjct: 166 TRVPLARRVGKDEETVPVDFIFPVERRDGVRSEIHDVPVAFTSVDRAYSPRPVWRSTLTL 225

Query: 221 D 221
            
Sbjct: 226 P 226


>UniRef50_Q2JH27 CRISPR-associated protein, CT1976 n=6 Tax=Actinomycetales
           RepID=Q2JH27_FRASC
          Length = 276

 Score =  143 bits (361), Expect = 4e-33,   Method: Composition-based stats.
 Identities = 70/258 (27%), Positives = 94/258 (36%), Gaps = 52/258 (20%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
            L+LRLAGP+Q+WG  +    R T   PT+SG++GLL A  G +R D   ++ L  S+  
Sbjct: 9   CLVLRLAGPLQSWGSRSMFNRRDTLTEPTKSGIIGLLAAAQGRRRTD--PIEDLL-SLTL 65

Query: 64  AVRCDELILDDRRVSVTGLRDYHTVLGARE-------------DYRGLKSHETIQTWREY 110
            +R D+          T LRDYHTV   R                    +  T  T R Y
Sbjct: 66  GIRTDQ--------PGTLLRDYHTVSDYRGRPLPSAAVSAKGLQKPTSPAKHTHVTERFY 117

Query: 111 LCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQAS----- 165
           L DA F  AL        V++ L  A+  P +   LGRR+CP THPL L           
Sbjct: 118 LQDAVFVAALAAP---EPVLTTLADALRTPAFPLALGRRACPPTHPLLLVPDSEPDAALW 174

Query: 166 --DPQKALLNYEPVGGDIYSEES----------------VTGHHLKFTARDEPMITLP-- 205
                + L          + +                  V          D P    P  
Sbjct: 175 SGSALEVLRQVPWQARPDHRDALARRRPPRLRRIDLPVTVDDPDGDDVRIDLPTTFDPHQ 234

Query: 206 RQFASREWYVIKGGMDVS 223
           R F SR  +     +   
Sbjct: 235 RGFTSRRVHQSWVHLPPP 252


>UniRef50_B0S4B6 Putative uncharacterized protein n=1 Tax=Finegoldia magna ATCC
           29328 RepID=B0S4B6_FINM2
          Length = 228

 Score =  143 bits (361), Expect = 4e-33,   Method: Composition-based stats.
 Identities = 54/234 (23%), Positives = 98/234 (41%), Gaps = 31/234 (13%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            S ++L+ A P+Q+WG       R T  +PT+S ++GL+ A  G ++ DT S++ L+ S+
Sbjct: 1   MSVILLKFASPLQSWGGLANYEIRNTEYYPTKSAVIGLVAAAFGYKKTDTESIKRLN-SL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHE---TIQTWREYLCDASFTV 118
            F+VR D+          + +RD+   +     Y     +    +    + Y+ DA F +
Sbjct: 60  NFSVRIDQ--------KGSLIRDFQIAMEYNPKYMPNDPNYFVKSNLIQKYYIQDAKFLI 111

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVG 178
           AL        ++ ++  A+  P Y  +LGR+S P+     +G    ++  + + +YE + 
Sbjct: 112 ALS--SDDETLMEDVYNALESPAYQLFLGRKSNPINADYLIGKFDGNEL-EIIKDYEWLA 168

Query: 179 GDIYSEESVTG--------------HHLKFTARDEPMIT--LPRQFASREWYVI 216
              Y +                      K   RD         R F+SR  Y  
Sbjct: 169 SKWYKKSIKKDSVELSIFSDYIDTGSKEKLIRRDLTESFENTKRDFSSRFEYRY 222


>UniRef50_B3E5U9 CRISPR-associated protein Cas5 family n=2 Tax=Desulfuromonadales
           RepID=B3E5U9_GEOLS
          Length = 271

 Score =  142 bits (358), Expect = 9e-33,   Method: Composition-based stats.
 Identities = 74/272 (27%), Positives = 105/272 (38%), Gaps = 66/272 (24%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             YL+ RL GP+ +WG+     +R +  +P +S LLGL+ A LGI+RD+     AL+   
Sbjct: 1   MKYLLFRLYGPLASWGEIAVGESRHSAVYPGKSALLGLIAAALGIRRDEEQRQAALASGY 60

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAR------------EDYRGLKSHETIQTWRE 109
           +FAV+               LRDYHT                 E   G +   TI + RE
Sbjct: 61  RFAVKVIST--------GHPLRDYHTAQAPDSVGKFVYRTRRDELVLGKERLGTILSSRE 112

Query: 110 YLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQK 169
           Y CDA   VA+     A   + E+ +A++KPR+  YLGR+SCP+  PL      A     
Sbjct: 113 YRCDAFSLVAVVAEDDAPYSLDEIREALMKPRFHLYLGRKSCPVAAPLNPLVRDAVGFGD 172

Query: 170 ALLNYEP-------VGGDIYSEESVTGHHLK----------------------------- 193
           AL +Y                +E V G  L                              
Sbjct: 173 ALDSYPYGALFVSSWLMKTAQKEIVEGGKLAEVPSLAKFSREDETVFAYNKQPVRYYWEG 232

Query: 194 ----------FTARDEPMITLPRQFASREWYV 215
                      T  D+P+     QF+ R  Y+
Sbjct: 233 DAGDLVSQQSLTRHDQPLSRNRWQFSQRTEYL 264


>UniRef50_D0MET6 CRISPR-associated protein Cas5 family n=1 Tax=Rhodothermus marinus
           DSM 4252 RepID=D0MET6_RHOM4
          Length = 252

 Score =  139 bits (349), Expect = 9e-32,   Method: Composition-based stats.
 Identities = 55/226 (24%), Positives = 88/226 (38%), Gaps = 11/226 (4%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L+LR   P+ ++G P  +       +P  S + GLL   LG    +T+ L+ L E +
Sbjct: 1   MEILLLRFDAPLMSFGAPIVDQYGFIQPYPALSMMTGLLANALGYTHAETARLERLQERL 60

Query: 62  QFAVRCDELILDDRRVSVTGL-------RDYHTVLGAREDYRGLKSH-ETIQTWREYLCD 113
           ++AVR D      R      L           T  G  E  +G  +        R+Y  D
Sbjct: 61  RYAVREDRRGQQLRDFQTVDLSQPFLHDERAWTTRGTLETRQGGTASLGIHIRLRDYWAD 120

Query: 114 ASFTVALWLTPHAT-MVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALL 172
           A +TVAL L P      +++LE+A+  P    ++GR+ C    PLF+G  +A+D   AL 
Sbjct: 121 AVYTVALTLDPPDEPPTLADLEQALRFPARPLFIGRKPCLPAAPLFIGRVEAADLLDALR 180

Query: 173 NYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKG 218
               +       +              P+    R+   R     + 
Sbjct: 181 RAP-LDARADRADFYRVWWETGPDDPPPVE-GIRENLRRPVTDRRD 224


>UniRef50_C9M9R7 CRISPR-associated protein Cas5, Ecoli subtype n=1 Tax=Jonquetella
           anthropi E3_33 E1 RepID=C9M9R7_9BACT
          Length = 243

 Score =  139 bits (349), Expect = 1e-31,   Method: Composition-based stats.
 Identities = 56/214 (26%), Positives = 87/214 (40%), Gaps = 3/214 (1%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             +L+LR  GPM ++G    +  RP  RFP  S + GL+   LG    +T  LQAL + +
Sbjct: 1   MDFLVLRFRGPMMSFGDVAVDEQRPIDRFPGVSMVTGLVANALGWDWSETEKLQALQDRL 60

Query: 62  QFAVRCDELILDDRRVSVTGL--RDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
             AVR D      R      L  +    V  +    R L    T+Q +  Y  ++  T  
Sbjct: 61  VLAVREDRAGERLREYQTVALPGKSGLFVTHSIPCSRNLDKPMTVQKYLSYWANSLITCF 120

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLG-TCQASDPQKALLNYEPVG 178
           + LT   T  + E+  A+ KP    +LGR++C  T P+F G    A  P++A+L    + 
Sbjct: 121 IALTGLGTPTLDEIACALKKPARPLFLGRKTCLPTEPVFRGEIFGAESPEEAVLRSCQLD 180

Query: 179 GDIYSEESVTGHHLKFTARDEPMITLPRQFASRE 212
                        +     D   +    +   R 
Sbjct: 181 KRPLKFVESPHSCVVEWPYDGRTVVSQSEIFERR 214


>UniRef50_Q1J367 CRISPR-associated protein, CT1976 n=1 Tax=Deinococcus geothermalis
           DSM 11300 RepID=Q1J367_DEIGD
          Length = 232

 Score =  137 bits (346), Expect = 2e-31,   Method: Composition-based stats.
 Identities = 60/229 (26%), Positives = 90/229 (39%), Gaps = 25/229 (10%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + L+LRL  PMQAWG  +    R T   P++SG+LGL  A LGI R D+    A    +
Sbjct: 1   MATLLLRLVAPMQAWGTRSRFDDRDTEAEPSKSGVLGLCAAALGIDRADSVEHLA---RL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
            F VR D               DYHT         G     T  T R YL DA+F   L 
Sbjct: 58  AFGVRVDR--------EGVAGTDYHTAQ----LRPGNPRTRTDVTRRAYLADAAFWAGLE 105

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPV---- 177
                  ++++L+ A+  P +   LGR++ P + P+  G         AL     +    
Sbjct: 106 ---GDAGLLTDLDAALHNPHWPLSLGRKAFPPSLPICAGPPLEVSLWDALRTAPSLRWRD 162

Query: 178 ---GGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVS 223
                 +  +       L+  A       +P    +R  Y+ +  + V+
Sbjct: 163 DDEPYRLVLDREAVPQPLRAAASPSRRQDVPDGPFARRRYLSRDVLTVT 211


>UniRef50_Q0BSC7 Putative uncharacterized protein n=1 Tax=Granulibacter bethesdensis
           CGDNIH1 RepID=Q0BSC7_GRABC
          Length = 225

 Score =  137 bits (346), Expect = 2e-31,   Method: Composition-based stats.
 Identities = 58/231 (25%), Positives = 91/231 (39%), Gaps = 35/231 (15%)

Query: 1   MRS--YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRD-DTSSLQAL 57
           M    +L+  LA  + + G+      R +  +PTRS ++GL+GA LGI+RD D S+L  L
Sbjct: 1   MMQQPFLVFGLAASLGSMGELAGHERRGSLIWPTRSAIIGLMGAALGIERDGDFSALDVL 60

Query: 58  SESVQFAVRCDELILDDRRVSVTGLRDYHTV------------LGAREDYRGLKSHETIQ 105
           S  V                +   LRDYHT+                          T  
Sbjct: 61  SIDVAI------------FDAGAPLRDYHTIETIPSAAAKNPNSRPEALRDARGRTNTAI 108

Query: 106 TWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQAS 165
           T R+Y     + +A+         +  +  A+L+P +T Y+GR+SCPL  P      +A 
Sbjct: 109 THRDYRTSVFYGIAVRGAG-----LERIVAALLEPHFTLYVGRKSCPLAAPTGAKIVEAV 163

Query: 166 DPQKALLNYE---PVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREW 213
             + AL + +        + +   VT         D P+      FA+R  
Sbjct: 164 SAEAALEHLKAPLWRKESVKAHLLVTDDPEGEVVTDVPLDRSSWHFATRRV 214


>UniRef50_B4UE71 CRISPR-associated protein Cas5 family n=2 Tax=Anaeromyxobacter
           RepID=B4UE71_ANASK
          Length = 246

 Score =  137 bits (344), Expect = 4e-31,   Method: Composition-based stats.
 Identities = 60/233 (25%), Positives = 91/233 (39%), Gaps = 15/233 (6%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M   LILR   P+ A+G    +     G FP  S + GL+   LG    D   L+AL   
Sbjct: 1   MLDALILRFDAPLLAFGGVAVDNHGEVGDFPGLSMVAGLIANALGYDHRDCDRLEALQRR 60

Query: 61  VQFAVRCDELILDDRRVSVT-----GLRDYHTVLGAREDYRGLKSHETIQTWREYLCDAS 115
           ++ AVR D                  L    T  GA E   G  S  T   +R Y  DA 
Sbjct: 61  LRIAVRRDRSGQRLVDFQTVALGQPFLERGWTTRGAVEGRDGAFSDGTHIRYRAYWADAV 120

Query: 116 FTVALWLTPHAT-MVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNY 174
           +T+A+ L P A    +  +E+A+ +P    +LGR++C  + P+  G  Q      AL ++
Sbjct: 121 YTLAVTLDPPAESPGLDAVERALREPERPLFLGRKACLPSVPILAGRLQIPSLLAALASF 180

Query: 175 EPVGGDIYSEESVTG--------HHLKFTARDEPMITLPRQFASREWYVIKGG 219
           E V  D +                      R+ P+    R +A++     +  
Sbjct: 181 ERVSKDRWEGGEPAPLAAWIPGSEAADPLVRELPVT-DERDWANQLVVGRRIV 232


>UniRef50_Q0AA33 CRISPR-associated protein Cas5 family n=2 Tax=Gammaproteobacteria
           RepID=Q0AA33_ALHEH
          Length = 242

 Score =  136 bits (343), Expect = 4e-31,   Method: Composition-based stats.
 Identities = 50/223 (22%), Positives = 75/223 (33%), Gaps = 8/223 (3%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              LILRL  P+ ++G    +   PT RFP RS L G+L   LG    DT +L +L   +
Sbjct: 1   MPCLILRLDAPLMSFGGVLVDQHNPTDRFPGRSMLTGMLANALGWHHQDTEALNSLQARI 60

Query: 62  QFAVRCDELILDDRRVSVTGLRDYH-------TVLGAREDYRGLKSHETIQTWREYLCDA 114
            +A R D      R      L   H       T         G       Q  R Y  + 
Sbjct: 61  SYAARWDVPPEPLRDYQTVDLGQTHLANPGWTTRGAPEHREGGTAKRGIHQRDRHYWANG 120

Query: 115 SFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNY 174
             TVA+ + P    V + L  A+  P    ++GR++C    P+ L   ++ D    L + 
Sbjct: 121 VMTVAVTVPPGEPNV-ATLAAALRHPARPLFIGRKACLPAAPVLLRVRESDDAYHVLASE 179

Query: 175 EPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIK 217
                               T          +       +  +
Sbjct: 180 PRDPRAAADTRFFEACWPPGTTAPATESRQRQNRTDDRDWRTQ 222


>UniRef50_A7ZDW7 Crispr-associated protein Cas5 n=3 Tax=Campylobacter
           RepID=A7ZDW7_CAMC1
          Length = 236

 Score =  136 bits (342), Expect = 6e-31,   Method: Composition-based stats.
 Identities = 38/200 (19%), Positives = 67/200 (33%), Gaps = 11/200 (5%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            S +  RL G    +  P    +  T   P ++ ++G LGA +G   +D   L  +  SV
Sbjct: 1   MSIVAFRLFGDYAHFSHPATIYSSLTYPVPPKTTIMGFLGAVIGE--EDYFKLSNIQYSV 58

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +   +  +       +      + H             + E  Q +RE +C  S+ V L 
Sbjct: 59  KIDRQILKKSFVFNGIKFALSSNMHIE------EGYQNAKEKKQFYRELICSPSYVVFLN 112

Query: 122 LTPHATMVISELEKAVL--KPRYTPYLGRRSCPLTHPLF-LGTCQASDPQKALLNYEPVG 178
           L         ++   +   K  +TPYLG   C        +  C+     ++ +N   + 
Sbjct: 113 LENLEQSYQDKIISNLKEHKTAFTPYLGINFCIADFSWIDIKICEKISQDESFINTFTLM 172

Query: 179 GDIYSEESVTGHHLKFTARD 198
            D   E       L      
Sbjct: 173 DDFVFEGINENAKLTTARMP 192


>UniRef50_A9HLC6 CRISPR-associated protein Cas5 family n=11 Tax=Acetobacteraceae
           RepID=A9HLC6_GLUDA
          Length = 260

 Score =  134 bits (337), Expect = 2e-30,   Method: Composition-based stats.
 Identities = 60/260 (23%), Positives = 86/260 (33%), Gaps = 52/260 (20%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M  +L   +  PM ++G       R     P RS +LGL+ ACLG+ RDD  +  AL+  
Sbjct: 1   MGQFLTFAMVAPMASFGAIAVGERRDGWDRPARSAVLGLMAACLGLTRDDEDAQAALAAD 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHE------------TIQTWR 108
              A+                L DYHT   A        +              TI + R
Sbjct: 61  YGLAI--------LCHAPGKLLTDYHTAQAAPARRNWRPATRAEELAASPGDLATILSRR 112

Query: 109 EYLCDASFTVALWLTPH-ATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDP 167
           +Y        A+W +   A   +  L+ A+ +P +TP LGRRSCP   PL          
Sbjct: 113 DYRMGTWHLGAVWTSGKTARWSLEALQAAMREPVFTPSLGRRSCPAGLPLAPSVTDGVSA 172

Query: 168 QKALLN-------------------------------YEPVGGDIYSEESVTGHHLKFTA 196
              LL+                                     D+           +   
Sbjct: 173 AAVLLDRHRNGPEAGLRIRHDSFRRQFAGASRSGGLLLVLDAVDMAEHGGGHTPLRREIR 232

Query: 197 RDEPMITLPRQFASREWYVI 216
           RD+P+     QF  RE  V+
Sbjct: 233 RDQPLSRRRWQFGLREEAVL 252


>UniRef50_B8IZA7 CRISPR-associated protein Cas5 family n=1 Tax=Desulfovibrio
           desulfuricans subsp. desulfuricans str. ATCC 27774
           RepID=B8IZA7_DESDA
          Length = 249

 Score =  133 bits (334), Expect = 6e-30,   Method: Composition-based stats.
 Identities = 53/215 (24%), Positives = 86/215 (40%), Gaps = 13/215 (6%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE---- 59
            L LRL  PM ++G  +    R T   P++S + G+L A  G+ R        L +    
Sbjct: 7   CLALRLQAPMLSFGNESRFNRRCTASLPSKSVVAGMLCAAKGLHRGSVEEQAFLQQVAAI 66

Query: 60  -SVQFAV-RCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFT 117
             +  A+ RC      D  ++     D+HTV G R+   G    +   T R YL D+SF 
Sbjct: 67  PMLSVAIPRCLSANGKDWLLAAGRTVDFHTVQGTRKAAGG--IKDCHITTRHYLHDSSFA 124

Query: 118 VALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTC--QASDPQKALLNYE 175
           V L        V+ +  +A+  P +  ++GR+ C  + P+F G    +A      L    
Sbjct: 125 VFL---NGPYRVLEDAARALQNPVWGLWIGRKCCIPSAPVFGGLFSSEAVALNHMLDAPL 181

Query: 176 PVGGDIYSEESVTGHHLKFTARDEPMITLPRQFAS 210
                     S    +     + E  ++  R+FA 
Sbjct: 182 EFFTHEREVHSFEDGNDTVPDQAESFLSAARRFAP 216


>UniRef50_Q3AA65 CRISPR-associated protein Cas5, Hmari subtype n=1
           Tax=Carboxydothermus hydrogenoformans Z-2901
           RepID=Q3AA65_CARHZ
          Length = 248

 Score =  132 bits (333), Expect = 8e-30,   Method: Composition-based stats.
 Identities = 44/231 (19%), Positives = 81/231 (35%), Gaps = 21/231 (9%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSL---QAL 57
           MR  ++  + GP   + +     +  +  FP R+ L G++ A LG+ +D   SL      
Sbjct: 1   MRKVIVFEIRGPAAHFRKFYTNSSSLSYAFPARTTLAGIIAAVLGLPKDSYYSLLTGNKA 60

Query: 58  SESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAR--EDYRGLKSHETIQTWREYLCDAS 115
             +++      +++   + V    L++ +   G         L        +R Y     
Sbjct: 61  HYALRLMTPVRKIMQTVKFVRTKTLKEVNGSGGPTMIPTEIILPVRGRELIYRVY----- 115

Query: 116 FTVALWLTPHATMVISELEKAV-LKPRYTPYLGRRSCPLTHPL---FLGTCQASDPQKAL 171
                           EL K + L P++  YLGR            F GT   ++    +
Sbjct: 116 ------FYHDDPSFQEELAKQLALGPKFPVYLGRSEFLAKIDFLGVFPGTALETNFVDTV 169

Query: 172 LNYEPVGGDIYSEESVTGHHLKFTARDEPMITLP-RQFASREWYVIKGGMD 221
           +N E +  +     ++ G  L++     P    P R  AS    V + G  
Sbjct: 170 VNLELLKDEELLFSTLHGEDLRYLKEKMPFSFNPDRSIASTASVVYEIGGK 220


>UniRef50_Q2FNU0 CRISPR-associated protein, CT1976 n=1 Tax=Methanospirillum hungatei
           JF-1 RepID=Q2FNU0_METHJ
          Length = 225

 Score =  131 bits (329), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 50/216 (23%), Positives = 79/216 (36%), Gaps = 38/216 (17%)

Query: 35  GLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLG---- 90
            +LG++ A LGI+RDD  +   L     F+V   +            ++D+HT+      
Sbjct: 15  AVLGMVAAALGIRRDDEEAQNRLQAGYGFSVMVLQ--------PGIMIQDFHTIQSVHSS 66

Query: 91  ---------AREDYRGLKSHETIQTWREYLCDASFT--VALWLTPHATMVISELEKAVLK 139
                     R D   L   ETI + REYLCD      V +     A   + E+  +   
Sbjct: 67  SLKKMNHVMTRRDEMNLGDSETILSRREYLCDHVSVACVWIRDAESAQFSLEEIAASFRN 126

Query: 140 PRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNY---------EPVGGDIYS------E 184
           P +  YLGR+SCP   P+     QA   + AL+ +           V   +        +
Sbjct: 127 PVFCLYLGRKSCPPALPVHARVIQADSLKSALVQHIEGFDLLNGFRVPDRVSLYFEDGID 186

Query: 185 ESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGM 220
                  +    RD  +     QF+ R  Y  +  +
Sbjct: 187 IGFDDPVMVMKRRDNILSRSRWQFSDRNEYYARISV 222


>UniRef50_B8FDI0 CRISPR-associated protein Cas5 family n=3 Tax=Bacteria
           RepID=B8FDI0_DESAA
          Length = 240

 Score =  128 bits (322), Expect = 1e-28,   Method: Composition-based stats.
 Identities = 65/240 (27%), Positives = 96/240 (40%), Gaps = 29/240 (12%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
            YL++ L  P+Q+WG  +  G R T  FPTRSG+LGLL   LG   +    L  L+   Q
Sbjct: 4   RYLLMWLEAPLQSWGADSKFGRRDTLPFPTRSGVLGLLLCALGASGEQKELLARLAPYGQ 63

Query: 63  FAVRC------DELILDDRRVSVTGLRDYHTVLGAREDYRGLK--------------SHE 102
             + C            ++      LRD+H V  A  D    +                 
Sbjct: 64  TVISCAGGRPGRSGGSPEKIPRQPLLRDFHMVGSAYNDKDPWERLHIPKTNEGKPAVGGG 123

Query: 103 TIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTC 162
              T+R YL DA F V L L P    +  +  +A+  P +  YLGR++C  T  ++ G  
Sbjct: 124 AKLTYRYYLQDARFAVILELPPD---LAEDFAQALQNPVWDIYLGRKNCAPTEFVYQGVF 180

Query: 163 ----QASDPQKALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLP-RQFASREWYVIK 217
                A D   AL+  + +  D              T  D P+   P +++  R   VI+
Sbjct: 181 DSQKDAMDRAAALMEEKELMEDF-RVVDGEHPGEPITLNDVPLQFGPMKKYRDRRVTVIR 239


>UniRef50_B4TTX2 CRISPR-associated protein Cas5 n=15 Tax=Enterobacteriaceae
           RepID=B4TTX2_SALSV
          Length = 241

 Score =  128 bits (321), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 66/235 (28%), Positives = 95/235 (40%), Gaps = 33/235 (14%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M+ YL+ +L  P+ +WG+      R +   PTRS LLGLL A LGI+RD+ + L   +  
Sbjct: 1   MKEYLVFQLYAPLASWGEEASGEIRHSATVPTRSALLGLLAAALGIRRDEEARLNNFNRH 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL------------KSHETIQTWR 108
              AV                LRDYHTV   RE+ +                  T+ + R
Sbjct: 61  YHLAVHAL-------ASQDRWLRDYHTVSAPRENKKYRYYTRRDELTLAPDEVGTLISQR 113

Query: 109 EYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQA---S 165
           EY CD  + VA+  TP A   +SEL +A+L P +  YLGR+SCPL  PL           
Sbjct: 114 EYRCDGYWHVAISATPDAPHSLSELREALLTPHFPLYLGRKSCPLALPLAARLMTGTLKE 173

Query: 166 DPQKALLNYEPVGGDIYSEESV----TGHHLKFTA-------RDEPMITLPRQFA 209
               A+          ++             +           ++P+     QF 
Sbjct: 174 VFTHAVEEISAAELSGFTLREGICYWDDPDEESLVWQQKQHSNNQPVSRQRWQFG 228


>UniRef50_D1Y486 Crispr-associated protein Cas5 n=1 Tax=Pyramidobacter piscolens
           W5455 RepID=D1Y486_9BACT
          Length = 269

 Score =  127 bits (320), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 64/229 (27%), Positives = 92/229 (40%), Gaps = 36/229 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              LILRL GP+ A+G    +  RPT   P  S + GL+   LG    D   LQ L E +
Sbjct: 1   MDALILRLRGPLMAFGDVAVDEIRPTDLLPGLSEMTGLIANALGWTFQDVEKLQRLQERL 60

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDY------------RGLKSHETIQTWRE 109
           + A R D             LRDY T   + ED              G K   T+Q +R 
Sbjct: 61  RLASREDRT--------GVPLRDYQTARLSSEDSLWRTDGIVAERGGGSKGEFTVQRYRH 112

Query: 110 YLCDASFTVALWLTPHAT-MVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQ 168
           Y  DA+ TV + L P      + E+  A+  P    ++GR  CP + P+           
Sbjct: 113 YRADAAVTVLIALDPADEAPALEEIRDALRHPARPLFIGRIGCPPSQPIC---------- 162

Query: 169 KALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIK 217
                +EP G +I   +S+    +  T R        R+ ASR   +++
Sbjct: 163 -----FEPEGREIIHTDSLKDAIMHITPRAPLGAQTKREPASRNKVLVE 206


>UniRef50_B8IMR2 CRISPR-associated protein Cas5 family n=1 Tax=Methylobacterium
           nodulans ORS 2060 RepID=B8IMR2_METNO
          Length = 273

 Score =  127 bits (320), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 49/216 (22%), Positives = 74/216 (34%), Gaps = 21/216 (9%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M + L+  L  P    G       R +   P RS +LGL+   LGI R D +   AL   
Sbjct: 1   MPAGLVFTLYAPFAGMGDVAVGEERGSFDRPARSAVLGLVAGALGIDRADEAGHAALDRG 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL----------KSHETIQTWREY 110
            + A+R               + DYHTV     D +                T+ + R Y
Sbjct: 61  YRLALRLR--------TPGCLVEDYHTVQAPPVDRKARWATRREALAVAGLNTLVSRRAY 112

Query: 111 LCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKA 170
             D    V + +          L  A+ +P + PYLGR+SCPL  PL     +      +
Sbjct: 113 RADPIVDV-VLIHVDEGPTPEALATALRRPTFAPYLGRKSCPLGLPLRPLWAEGVTRVGS 171

Query: 171 LLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPR 206
           LL    +     + +++                 P 
Sbjct: 172 LLAA--LDETFVTHDALDPEPTATVLDVLRRAYDPD 205


>UniRef50_B9MPU1 CRISPR-associated protein Cas5, Hmari subtype n=2 Tax=Clostridia
           RepID=B9MPU1_ANATD
          Length = 250

 Score =  126 bits (317), Expect = 4e-28,   Method: Composition-based stats.
 Identities = 35/232 (15%), Positives = 68/232 (29%), Gaps = 22/232 (9%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             +L+  L G    + +     +  +   P R+ + G++ A LG +RD    + + +E++
Sbjct: 1   MKFLVFDLKGKFAHFRKFYTNSSSLSYLVPPRTVIEGMVAAILGFERDSYYDMFS-AENL 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLC----DASFT 117
             AV+       ++   +    +Y       E        +      E L        F 
Sbjct: 60  LVAVQ-----KLEKTYKIVQTVNYIKAQTISELKNPNTHTQVPL---EILAGYNGFVGFR 111

Query: 118 VALWLTPHATMVISELEKAVL--KPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYE 175
           V +   P    + S L   +   K  +  Y G           LG  +A   + +     
Sbjct: 112 VFVM--PKDEKIYSFLRARLESGKSEFPIYFGSAPFAAKIEF-LGEFEACRWEDSRAGIL 168

Query: 176 PVGGDIYSEESV----TGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVS 223
            V      +           L       P      +FA++    I       
Sbjct: 169 TVLDTGLIKSLNLSLEFSSSLALMKDRMPCDFDKDRFATKVKTYIHDENLNP 220


>UniRef50_B5YBH8 CRISPR-associated protein Cas5, Hmari subtype n=1 Tax=Dictyoglomus
           thermophilum H-6-12 RepID=B5YBH8_DICT6
          Length = 250

 Score =  126 bits (316), Expect = 7e-28,   Method: Composition-based stats.
 Identities = 28/211 (13%), Positives = 67/211 (31%), Gaps = 9/211 (4%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              ++  L G M  + +     +  +  FP R+ ++GL+   LG +RD    + +  ++ 
Sbjct: 1   MKVIVFDLLGKMAHFRKFYTNSSSLSYHFPPRTTIVGLIAGLLGYERDTYYEIFSTDKA- 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +  +     +    +V      +    L            E I   ++   D  + +   
Sbjct: 60  KITIGVKSPLRKILQVVNYVWAENVKQLNQSRGQHTQIPLE-IIFPQDMKEDICYRIF-- 116

Query: 122 LTPHATMVISELEKAVLK--PRYTPYLGRRSCPLTHPLF-LGTCQASDPQKALLNYEPVG 178
                  ++ +L+  ++     + PYLG             G  + S   K L++     
Sbjct: 117 FHHKDEKIMEDLKNKLVNFDFCFPPYLGITEFVGKVDFIGEGMAEISRADKVLIDSVVSV 176

Query: 179 GDIYSEESV--TGHHLKFTARDEPMITLPRQ 207
             I     +       ++     P+     +
Sbjct: 177 DYIKKNSLILEPQVGAQYVKEKMPLSFNKDR 207


>UniRef50_C8PE23 CRISPR-associated protein Cas5 n=1 Tax=Campylobacter gracilis
           RM3268 RepID=C8PE23_9PROT
          Length = 237

 Score =  125 bits (315), Expect = 8e-28,   Method: Composition-based stats.
 Identities = 31/199 (15%), Positives = 69/199 (34%), Gaps = 11/199 (5%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              +   L+G    +  P    +  T   P ++ ++GLLGA +G    +   L  +  SV
Sbjct: 1   MDIIAFELSGDYAHFSHPATIYSSLTYPVPPKTAIMGLLGAIIGE--MNYFKLNDIGYSV 58

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
             + +  +  +    +        H   G         S E  Q ++E + D  + + + 
Sbjct: 59  ILSSQFRKKTMIFNGIKFALSSSMHIEQG------YQDSSEKKQFYKELIKDPRYVIFVD 112

Query: 122 LTPHATMVISELEKAVL--KPRYTPYLGRRSCPLTHP-LFLGTCQASDPQKALLNYEPVG 178
           L+         +  ++   +  +TPYLG   C      + +  C+    +++ ++   + 
Sbjct: 113 LSALNASYKENIIDSLKAHRCVFTPYLGINFCIADFKYIEIKNCELVHEKESFIDTFVLM 172

Query: 179 GDIYSEESVTGHHLKFTAR 197
            D   +       L     
Sbjct: 173 DDFIFDAQSFDIRLTTARM 191


>UniRef50_B0K553 CRISPR-associated protein Cas5, Hmari subtype n=4
           Tax=Thermoanaerobacter RepID=B0K553_THEPX
          Length = 236

 Score =  125 bits (314), Expect = 1e-27,   Method: Composition-based stats.
 Identities = 34/230 (14%), Positives = 68/230 (29%), Gaps = 28/230 (12%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
            +I  L G    + +     +  T   P R+ + G++ A LG +RD        +E++  
Sbjct: 1   MVIFDLWGKFAHFRKFYTNSSSLTYSVPPRTTVEGMIAALLGYERDTYYEKLN-AENLYV 59

Query: 64  AVR----CDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
           AVR      +++     +  T L + H      +    L   ++   +R Y+        
Sbjct: 60  AVRKMSKTKKIMQSVNYIKATTLGELHFPKQHTQIPFELLISDSKIRYRFYII------- 112

Query: 120 LWLTPHATMVISELEKAV--LKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLN---- 173
                    +  E+++ +    P +  Y G          ++   +      A       
Sbjct: 113 ----HKDENIFREIKERLFKKAPVFPLYFG----SAPFSCYIDYVEEVTWDWATSEDFQD 164

Query: 174 -YEPVGGDIYSEESVTGHHLKFTARDEPMITL-PRQFASREWYVIKGGMD 221
            Y  +  D   E  +            P      R       YV +    
Sbjct: 165 IYSVMPSDKIKEIDIKNMKGYLLKERMPRDFGIDRTIKEVTTYVYEDVGH 214


>UniRef50_A5D0Y3 Putative uncharacterized protein n=1 Tax=Pelotomaculum
           thermopropionicum SI RepID=A5D0Y3_PELTS
          Length = 242

 Score =  125 bits (313), Expect = 1e-27,   Method: Composition-based stats.
 Identities = 45/227 (19%), Positives = 72/227 (31%), Gaps = 21/227 (9%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
             L+  + G +  + QP    T  T  FP R  + GLL + LG+  DD +    L E   
Sbjct: 4   QVLVFSIKGSLAHFRQPDTTATHATYPFPPRPTIHGLLASVLGLDFDDEAGAAFLHEEHF 63

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWL 122
             +   + +                 +  +    G        T  E +    + V    
Sbjct: 64  VGLSLLKPVRTVCA---------QMSMHGKGFTGGGGDSFNRLTTIELVVSPHYLVYYTG 114

Query: 123 TPHATMVISELEKAVL--KPRYTPYLGRRSCPLTHPLFLGTCQ----ASDPQKALLNYEP 176
           +      + EL + +   +  Y  YLG  +  LT P+F G       A   ++ L     
Sbjct: 115 SR-----LGELAERIRTGQSVYHTYLG-SAYCLTFPVFHGLYPLLEVAPGEEEPLPCSSV 168

Query: 177 VGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVS 223
           V   +  E  V        AR  P   +  +F  R   VI       
Sbjct: 169 VPQGVIQEILVEPGGNYAVARALPYRHVGGRFFERTLNVIYEVNGKP 215


>UniRef50_Q1AZD3 CRISPR-associated protein, Cas5h family n=1 Tax=Rubrobacter
           xylanophilus DSM 9941 RepID=Q1AZD3_RUBXD
          Length = 258

 Score =  123 bits (310), Expect = 3e-27,   Method: Composition-based stats.
 Identities = 41/233 (17%), Positives = 77/233 (33%), Gaps = 19/233 (8%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
            LI  L G    + +     +  +  FP R+ L GL+   +G +RD  +   +L E  Q 
Sbjct: 6   LLIFDLCGAYGMFRKFYTNSSSLSYPFPPRTTLAGLIAGMMGCERDSYAEDLSL-ERCQI 64

Query: 64  AVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLC------DASFT 117
           AV     +    +     + + H        + G      IQ   E++       +  + 
Sbjct: 65  AVSVITPVRRVMQQVNYVMTEGHVWTKNTGGFDGS--SGPIQVPVEWVFPEVGHRELRYR 122

Query: 118 VALWLTPHATMVISELEKAVLK--PRYTPYLGRRSCPLTHPLFLGTCQASDP---QKALL 172
           V    T      +  L + +    P Y PYLG   CP      + T +       +  L 
Sbjct: 123 VY--ATHEDRGWLKRLAEILEGGVPIYPPYLGMSECPGRVE-HVATLEGWGLGHREDELP 179

Query: 173 NYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQ--FASREWYVIKGGMDVS 223
               +  +  S        ++      P+    R+   A+ +    + G  ++
Sbjct: 180 VRTVLPSEAVSGPPRLEEGVQIVKERIPLALDERRRLIAAADVLYNRAGPHIT 232


>UniRef50_B6B783 CRISPR-associated protein Cas5, Ecoli subtype n=1
           Tax=Rhodobacterales bacterium Y4I RepID=B6B783_9RHOB
          Length = 232

 Score =  123 bits (310), Expect = 3e-27,   Method: Composition-based stats.
 Identities = 62/232 (26%), Positives = 86/232 (37%), Gaps = 39/232 (16%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRD-DTSSLQALSE 59
           M  YLI +L   + A G+      R +   P RS ++G LGA +G++RD D S L AL  
Sbjct: 1   MPEYLIFQLVAAIGAMGEFGGHDRRGSLTLPGRSAVIGTLGAAMGLRRDADFSGLDALGV 60

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLG------------AREDYRGLKSHETIQTW 107
           +V                     RDYHTV               +      +   T  T 
Sbjct: 61  AVA------------SFGKTAPFRDYHTVQTVPSAAVKRPQSRPQALRDAGRKVNTTLTS 108

Query: 108 REYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDP 167
           R+Y  D  F VA+W        ++EL  A+  P +  +LGR+SCPL+ P       A+ P
Sbjct: 109 RDYRADCVFGVAIWGEG-----LAELASALSAPVFQTFLGRKSCPLSAPFDPQIVAAATP 163

Query: 168 QKAL--LNYEPVGGDIYSEESVTGHHLKF-------TARDEPMITLPRQFAS 210
             AL  L   P  G    +  V              T  D  +      F  
Sbjct: 164 SAALSQLRLPPWIGAREMDMIVADEGTDLGAPSILETRHDRALDRTLWHFGK 215


>UniRef50_A3DKB9 CRISPR-associated protein Cas5, Hmari subtype n=2 Tax=Clostridium
           thermocellum RepID=A3DKB9_CLOTH
          Length = 237

 Score =  123 bits (310), Expect = 4e-27,   Method: Composition-based stats.
 Identities = 32/223 (14%), Positives = 71/223 (31%), Gaps = 22/223 (9%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
            YL+  ++     + +P    +  T   PTR+ + G++ A LG  ++D        ++ +
Sbjct: 4   KYLVFDISASYGHFKKPYTTTSPLTYSIPTRTAVSGIIAAVLGFGKEDYQEHFTKPQA-K 62

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWL 122
            A+     +   R                         HE  Q   E+L DA + +    
Sbjct: 63  IAIGIRNPVKKVRISENLINTK----------KSMNIIHERTQIKIEFLKDACYRIY--F 110

Query: 123 TPHATMVISELEKAVL--KPRYTPYLGRRSCPLTHPLFLGT--CQASDPQKALLNYEPVG 178
           T     +   L++++   +  YT  +G       +         +    ++ +     V 
Sbjct: 111 THTDKQIYERLKESLKEHRTVYTISMGLSENLANYTFTGEFDGREVKGNKEIVEFSSVVP 170

Query: 179 GDIYSEESVTGHHLK-FTARDEPMITLPRQFASREWYVIKGGM 220
            DI  +  +     + +     P+       A R     +  +
Sbjct: 171 LDILKKGDIEFEDDREYFTETIPVEMD----AERNINEYREVL 209


>UniRef50_B5F422 CRISPR-associated protein Cas5 n=59 Tax=Enterobacteriaceae
           RepID=B5F422_SALA4
          Length = 248

 Score =  123 bits (308), Expect = 5e-27,   Method: Composition-based stats.
 Identities = 69/255 (27%), Positives = 100/255 (39%), Gaps = 39/255 (15%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M  YL+ +L GPM +WG       R +   P+RS LLGLL A LGI+RD+   L A +  
Sbjct: 1   MSQYLVFQLHGPMASWGVDAPGEVRHSHELPSRSALLGLLAAALGIRRDEEERLNAFNRH 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHET-----------IQTWRE 109
            QF        L     +    RDYHTV   +E  +                  + + R+
Sbjct: 61  YQF--------LLCASGNPRWARDYHTVQMPKEVRKARYFSRREELQDPELLSALISRRD 112

Query: 110 YLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQK 169
           Y  DA + +A+  TP A   +++L+ A+  P +  YLGR+S PL  PL     + S    
Sbjct: 113 YYTDAWWMIAVSATPDAPYTLAQLQAALQHPVFPLYLGRKSHPLALPLAPQLLEGSAADV 172

Query: 170 ALLNYEPVGGDIYSEESV----------TGHHLKFT------ARDEPMITLPRQFASREW 213
               Y        + +             G H   T       RD P+      F  R  
Sbjct: 173 LREAYRWYQDQFNALKLPLPRLQNECWWEGEHDGLTASKILRRRDMPLSRQQWLFGERSV 232

Query: 214 ----YVIKGGMDVSQ 224
               ++ K    +SQ
Sbjct: 233 NQGPWLRKEDACISQ 247


>UniRef50_C5V9N1 CRISPR-associated protein Cas5 n=1 Tax=Corynebacterium matruchotii
           ATCC 14266 RepID=C5V9N1_9CORY
          Length = 223

 Score =  122 bits (305), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 51/226 (22%), Positives = 77/226 (34%), Gaps = 25/226 (11%)

Query: 1   MRSYLILRLAGPMQAWGQPT-FEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE 59
           M   L +RLAGP+Q+W  P        T   PTRSGL+GLL    G  R +         
Sbjct: 1   MTEALYIRLAGPLQSWAGPAITGNFVRTEPRPTRSGLVGLLAGACGYGRGEYPEWLT--- 57

Query: 60  SVQFAVRCDELILDDRRVSVTGLRD-------------YHTVLGAREDYRGLKSHETIQT 106
            + F +R D              RD                      +        T  T
Sbjct: 58  QLHFQIREDNRGTLVDDFHTINPRDTEEEFRSRLLLAMGQRPTKKLLNSTPDGQGLTAIT 117

Query: 107 WREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASD 166
            R Y+ D  F V +            L + + +P +  YLGR++   + P +LG    + 
Sbjct: 118 ERTYIADGEFIVQIKAGSREHQ--ELLAEKLQQPHFVTYLGRKAFAPSFPFYLG----AG 171

Query: 167 PQKALLNYEPVGGDIYSE--ESVTGHHLKFTARDEPMITLPRQFAS 210
           P   L     VGG+   +           +T    P++    Q+ +
Sbjct: 172 PDDTLARIPTVGGEEPKKILRFYALDDYGYTTTTVPVVKDRNQWLT 217


>UniRef50_B5GY62 Crispr-associated protein (Fragment) n=1 Tax=Streptomyces
           clavuligerus ATCC 27064 RepID=B5GY62_STRCL
          Length = 260

 Score =  121 bits (304), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 59/186 (31%), Positives = 82/186 (44%), Gaps = 28/186 (15%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
            L+LRLAGP+Q+WG  +   +R TG  PT+SG++GLL A     R   + ++ L  +++ 
Sbjct: 85  VLLLRLAGPLQSWGSASAFNSRQTGAEPTKSGVIGLLAAA--DGRARGACIEDLR-ALRL 141

Query: 64  AVRCDELILDDRRVSVTGLRDYHTVLGARE-------------DYRGLKSHETIQTWREY 110
            VR D           T LRDYHT    R                    +  T  T R Y
Sbjct: 142 GVRVDRS--------GTLLRDYHTASDHRGRPLAQAGVGAKGTQRPTSPAKYTQVTTRYY 193

Query: 111 LCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKA 170
           L DA F  AL        ++  L++AV  P +   LGRRSC  + PL LG        + 
Sbjct: 194 LQDAVFLAALA---GPRALLDRLDRAVRAPAFPLALGRRSCVPSLPLALGVHPG-SLGEV 249

Query: 171 LLNYEP 176
           L  +  
Sbjct: 250 LSTHPW 255


>UniRef50_C1DUR1 Crispr-associated protein Cas5, hmari subtype n=1
           Tax=Sulfurihydrogenibium azorense Az-Fu1
           RepID=C1DUR1_SULAA
          Length = 229

 Score =  120 bits (302), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 35/209 (16%), Positives = 72/209 (34%), Gaps = 19/209 (9%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L+  + G    + +     +  T   P  + + G++GA LGI + D   +   +E+ 
Sbjct: 1   MEVLVFDVWGDFGHFRKFYTTTSPLTFSIPPPTAVFGIIGAILGIDKKDYLKIIN-AETT 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           + A+   + +   R           T+          +         E+L DA + + + 
Sbjct: 60  KVAIEIVKPVKKIRF----------TINYIDTKVSFSRIKNRTPIRTEFLKDAHYRLYIN 109

Query: 122 LTPHATMVISELEKAVL--KPRYTPYLGRRSCPLTHPLFLGTCQASDPQKA-LLNYEPVG 178
           L      +  EL+  +   K  YT  LG  +       ++G  Q      +  +N     
Sbjct: 110 LN--EENLFRELKDRIKERKTYYTVSLGLANLIANFK-YIGQYQVEPLDASNYVNTVISS 166

Query: 179 GDIYSEESVTGHHLKFTARDEPMITLPRQ 207
            +I + E V G   ++     P+     +
Sbjct: 167 ENIENIEMVEGK--RYFKEKMPVDIDENR 193


>UniRef50_Q2NH81 Putative uncharacterized protein n=1 Tax=Methanosphaera stadtmanae
           DSM 3091 RepID=Q2NH81_METST
          Length = 235

 Score =  120 bits (300), Expect = 4e-26,   Method: Composition-based stats.
 Identities = 30/171 (17%), Positives = 57/171 (33%), Gaps = 11/171 (6%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + ++  + G    + +     +  T  FP+R+ + G +   LG  R+    L    E+ 
Sbjct: 1   MNLIVFDIWGDYAYFRRGYTTTSTLTYPFPSRTTIAGFIAGILGYPRNSYYDLF-QKENS 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +  ++    I   R          +T               T     E+L +  + + L 
Sbjct: 60  KIGLKIINPIKKTRINLNYI----NTKNSMLLSEIKGNGKRTQVP-AEFLKNVKYRIYLS 114

Query: 122 LTPHATMVISELEKAVL--KPRYTPYLGRRSCPLTHPLF-LGTCQASDPQK 169
           L      ++++L   +   K  YTPYLG   C     L   G       + 
Sbjct: 115 L--DDEEIMNKLYNTLKEHKSVYTPYLGITECLANFSLVGKGIYSTESIKG 163


>UniRef50_C2KP44 Putative uncharacterized protein n=1 Tax=Mobiluncus mulieris ATCC
           35243 RepID=C2KP44_9ACTO
          Length = 245

 Score =  118 bits (295), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 49/212 (23%), Positives = 77/212 (36%), Gaps = 23/212 (10%)

Query: 2   RSYLILRLAGPMQAW-GQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
            + + +RLAGP+Q+W G         T  +PTR  L GL+ ACLG  R          + 
Sbjct: 1   MTSVYIRLAGPLQSWAGAKVSGNISHTQDYPTRGSLEGLVAACLGCPRGKYPLWF---QD 57

Query: 61  VQFAVRCDELILDDRRVS--VTGLRDYHTVLGAREDYRGLKSHE------------TIQT 106
           +QFAVR D                 D            G ++              T   
Sbjct: 58  LQFAVRVDSPGRICDDYQTIGVRDEDMQVATRLLTLLTGKRATNRGLAFIPDAQGKTTIV 117

Query: 107 WREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASD 166
            R  L DA F V +         + +L++A+  P +  YLGR++     P +LG  + S 
Sbjct: 118 RRTLLADAEFIVQIQC----EGHLEQLDQAISDPTFVSYLGRKAFAPGFPFYLGIGEDSA 173

Query: 167 PQK-ALLNYEPVGGDIYSEESVTGHHLKFTAR 197
                + +   +    Y E+       +  +R
Sbjct: 174 IDTLPVFDKGRLESSYYQEKPEPTAESEIKSR 205


>UniRef50_D1CHV1 CRISPR-associated protein Cas5 n=1 Tax=Thermobaculum terrenum ATCC
           BAA-798 RepID=D1CHV1_THET1
          Length = 264

 Score =  116 bits (291), Expect = 6e-25,   Method: Composition-based stats.
 Identities = 31/218 (14%), Positives = 65/218 (29%), Gaps = 18/218 (8%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQ----RDDTSSLQALS 58
             +I  LAG    + +     +  +  FP R+ L GL+   +G +    R+  +   A  
Sbjct: 4   KMIIFDLAGAYAMFRKFYTNSSSLSYPFPPRTVLAGLIAGIMGYERQGHRNTYAEHLAPG 63

Query: 59  ESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDA---- 114
            +   A+     +    +     + + +        + G +  E   T  E++  A    
Sbjct: 64  VA-DIALSVRVPVRRVMQTVNYVMTEGNVWSRNAGGFDGSR--ERTLTPVEWVFPASGRR 120

Query: 115 --SFTVALWLTPHATMVISELEKAVLK-PRYTPYLGRRSCPLTHPLFLGTC--QASDPQK 169
              + V L         +      +     Y PYLG   CP            +    ++
Sbjct: 121 QLRYRVYLT--HRDEGWLERFAGYLRSGAVYPPYLGMTECPAVIEPVAEVEDWELGVREE 178

Query: 170 ALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQ 207
            L     +  D   +  +     +      P+     +
Sbjct: 179 VLPISTVINADKIVDLPLPDADAQIVKERMPIALDNDR 216


>UniRef50_B6XT64 Putative uncharacterized protein n=2 Tax=Bifidobacterium
           RepID=B6XT64_9BIFI
          Length = 212

 Score =  114 bits (285), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 49/197 (24%), Positives = 76/197 (38%), Gaps = 28/197 (14%)

Query: 39  LLGACLGIQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL 98
           +L +  G  R+D   ++ L   + F VR ++            +RD  T           
Sbjct: 1   MLASAQGRTRED--PIEDLL-GISFGVRVEQ--------RGRVIRDLQTEKSLTRKRNSR 49

Query: 99  K-SHETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPL 157
           K   E   T+R YL DA F VAL        V+  L++A+  P++  YLGRRSCP  +PL
Sbjct: 50  KFDKEMPLTYRYYLADACFLVAL---GADRSVLEMLDEAIHSPKWPLYLGRRSCPPNYPL 106

Query: 158 FLGTCQA-SDPQKALLNYEPVGGDIYSEE----------SVTGHHLKFTARDEPMITLP- 205
            LG      D ++AL +      + Y                      T  D P+     
Sbjct: 107 SLGIHDEYEDIRQALNSETWHASEWYRRRYRYPDLEIVCDAEKGENITTQSDLPLSFSRE 166

Query: 206 -RQFASREWYVIKGGMD 221
            R++A+R  +  +    
Sbjct: 167 GRRYANRAVHRYRIPNP 183


>UniRef50_A7HLK6 CRISPR-associated protein Cas5, Hmari subtype n=2
           Tax=Thermotogaceae RepID=A7HLK6_FERNB
          Length = 236

 Score =  113 bits (283), Expect = 4e-24,   Method: Composition-based stats.
 Identities = 26/223 (11%), Positives = 64/223 (28%), Gaps = 20/223 (8%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSL---QALS 58
             +L+  + G    + +     +  +   P R+ L G++ A LG +RD    +   Q L+
Sbjct: 1   MEFLVFDIKGKFAHFRKFYTNSSSLSYSIPPRTTLEGIIAAILGFERDSYYEILNAQKLN 60

Query: 59  ESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV 118
             ++ A    ++I     +      + +      +    + +      +R Y        
Sbjct: 61  IGLKKATPTRKIIQTLNYIKAKTPSNVYDPDEHTQIPFEIITSNDKVIYRVY-------- 112

Query: 119 ALWLTPHATMVISELEKAVLKPRYT--PYLGRRSCPLTHPLFLGTCQASDPQKALLNYEP 176
              +      ++ +LE  +   ++   PY G     ++  L           +  +    
Sbjct: 113 ---VNHVDQTIMEDLEYRLKNNKFCYIPYFGVAPFNISIDLKGKFQAEPKFSEDFVKVSS 169

Query: 177 VGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGG 219
           V              +       P          R    ++  
Sbjct: 170 VIRRNLISSLKVEEEVILLKEKMPRDFSR----ERTVIEMEDY 208


>UniRef50_A7BQN4 Protein containing DUF522 n=1 Tax=Beggiatoa sp. PS
           RepID=A7BQN4_9GAMM
          Length = 267

 Score =  112 bits (281), Expect = 7e-24,   Method: Composition-based stats.
 Identities = 34/211 (16%), Positives = 71/211 (33%), Gaps = 12/211 (5%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              ++  ++G    + +P    +  T  FP  + ++GLLGA LG  +++        +++
Sbjct: 22  MRCIVFDISGEYAHFKKPYSPMSPVTYPFPPPTAIMGLLGAILGYSKEEYHERLG-WQTL 80

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHE--TIQTWREYLCDASFTVA 119
           +  +R  +     R           T  G    +R        T   + E++   ++ + 
Sbjct: 81  RVGIRLLKPTQIFRAAINLL----QTKDGTDTFFRPKADKNSHTRVPY-EFVKSPAYRIY 135

Query: 120 LWLTPHATMVISELEKAVL--KPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPV 177
           +   P    V S+L   +   +  YTP LG  SC                 +    Y  V
Sbjct: 136 VMQLPD--NVASDLVAHLKTHRTVYTPVLGLASCLADVEWVGEWEAQPLAMQDWETYTVV 193

Query: 178 GGDIYSEESVTGHHLKFTARDEPMITLPRQF 208
                   +    + ++     P I   ++ 
Sbjct: 194 PLFENININYQQANRRYHRFRVPAIMDNQRI 224


>UniRef50_A6TQ83 CRISPR-associated protein Cas5 family n=9 Tax=Bacteria
           RepID=A6TQ83_ALKMQ
          Length = 259

 Score =  112 bits (280), Expect = 9e-24,   Method: Composition-based stats.
 Identities = 33/222 (14%), Positives = 71/222 (31%), Gaps = 19/222 (8%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
             + ++L      + +PT    + T   P  S ++G++ +    +  +   +    +   
Sbjct: 6   KAVRIKLYQETANYKKPTSFQLKETYPLPPYSTVIGMVHSLCDYK--EYKEMNISIQGKY 63

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWL 122
           F+   D     + +  +T     H +        G           E L +    + +  
Sbjct: 64  FSKTNDLFTRYEFKNGMTFDSTRHQIQ------VGDFGVGQGVATTELLVEVELLIHI-- 115

Query: 123 TPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDIY 182
            P    +I E+E+A L PR  P LGRR                      ++ + +  D+ 
Sbjct: 116 IPTDQDLIQEIEQAFLYPREYPSLGRREDLA-------VINEVTVVD--ISEKELEEDVV 166

Query: 183 SEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVSQ 224
            +E+   +      RDE ++    +   R            +
Sbjct: 167 LDENYAAYIPLKMIRDEEVVLDGAEPGIRSRGTRYKLTKNYE 208


>UniRef50_UPI00016C61FD CRISPR-associated protein Cas5, hmari subtype n=1 Tax=Clostridium
           difficile QCD-76w55 RepID=UPI00016C61FD
          Length = 250

 Score =  111 bits (277), Expect = 2e-23,   Method: Composition-based stats.
 Identities = 33/220 (15%), Positives = 71/220 (32%), Gaps = 22/220 (10%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTR--PTGRFPTRSGLLGLLGACLGIQRDDTSSLQALS 58
           M   L   L G   ++ +PT+  +    T     +  LLG+LGA +GI        + L 
Sbjct: 1   MDEVLKFNLKGKGASFSKPTYNSSSIIQTYPHIHKVALLGILGAIIGIDNTGYKRKKELP 60

Query: 59  ESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV 118
           +  +  ++  ++ +  ++++     D  T      +        T     E L + S+ +
Sbjct: 61  KFYKL-LKDLKIAIAPKKLNFNKCVDVVTDTSGFSNKISPNVGSTYLINYEILINPSWDI 119

Query: 119 ALWLTPHATMVISELEKAV--LKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEP 176
            +          ++++K +      + P+LGR        LF    +             
Sbjct: 120 YIL---GDGEYYNKIKKYILNRSAVFHPFLGRNH------LFADLSEVEILNGEFSKELS 170

Query: 177 VGGDIY--------SEESVTGHHLKFTARDEPMITLPRQF 208
                +         +E +    L       P+    R+ 
Sbjct: 171 KIDSFFISDNVVLDEDEILLNEKLYLFKDSMPISIDNRKI 210


>UniRef50_C0W6U0 CRISPR-associated Cas5 family protein n=1 Tax=Actinomyces
           urogenitalis DSM 15434 RepID=C0W6U0_9ACTO
          Length = 201

 Score =  110 bits (276), Expect = 2e-23,   Method: Composition-based stats.
 Identities = 50/200 (25%), Positives = 78/200 (39%), Gaps = 39/200 (19%)

Query: 39  LLGACLGIQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL 98
           +L A +G +R D   ++ L  S++F VR D+          T LRD+HT           
Sbjct: 1   MLAAAVGRRRTD--PIEDLL-SLRFGVRKDQ--------PGTVLRDFHTARTLDGKQS-- 47

Query: 99  KSHETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLF 158
                  + R YL DA +  A+        ++  L+ AV  P +  YLGRRSCP + PL 
Sbjct: 48  ----MPLSERYYLADAVYLAAIE---GEKTLLEGLDVAVRHPVFPLYLGRRSCPPSQPLS 100

Query: 159 LGTCQASDPQKALLNYEPVGGDIYSEE----------------SVTGHHLKFTARDEPMI 202
           LG   A    +AL +      D +                   +       +T  D P+ 
Sbjct: 101 LGIRHA-SLLQALTDEPWQAADWFRLRQDNSFRAEIVIDAASLAPDERGSGYTTLDSPVS 159

Query: 203 TLPRQ--FASREWYVIKGGM 220
             PR+  + +RE   +   +
Sbjct: 160 FDPRRRDYQAREVERLFVPV 179


>UniRef50_Q8PZD2 Putative uncharacterized protein n=1 Tax=Methanosarcina mazei
           RepID=Q8PZD2_METMA
          Length = 232

 Score =  110 bits (276), Expect = 3e-23,   Method: Composition-based stats.
 Identities = 28/208 (13%), Positives = 59/208 (28%), Gaps = 24/208 (11%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L+ R       + +P    +  T        + GL+GA LGI + +   +   +  +
Sbjct: 1   MDCLVFRAKSGYAKFRKPYTTTSALTFLCIHPPAVKGLIGAVLGIDKTE---IYRNTLDL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +  ++    +           +D   +          K         E+L D  + + + 
Sbjct: 58  KIGIQVLSPVR----------KDMQVLKLVSMKA--EKDLFNFPVNAEFLRDPEYRIFVS 105

Query: 122 LTPHATMVISELEKAVLK--PRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGG 179
             P     + ELE  +    P +TPYLG          +     A        +      
Sbjct: 106 WLPDK---LDELEDRLQNQMPIFTPYLGVSEYIAKLD-YEKRVNAELL---TKSSSIDSL 158

Query: 180 DIYSEESVTGHHLKFTARDEPMITLPRQ 207
                  +          + P+    ++
Sbjct: 159 VPSRFIDLQHSDYHIFTDNIPVSNNEKR 186


>UniRef50_A6UVX6 CRISPR-associated protein Cas5, Hmari subtype n=2
           Tax=Methanococcales RepID=A6UVX6_META3
          Length = 256

 Score =  110 bits (275), Expect = 4e-23,   Method: Composition-based stats.
 Identities = 25/173 (14%), Positives = 58/173 (33%), Gaps = 13/173 (7%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              ++  + G    + +     +  +  FP ++ + G+LGA LG+ ++D        ++V
Sbjct: 1   MKMIVFDIWGDYGHFKKIYTTTSPLSYDFPPKTSIYGMLGAFLGLDKEDYLKHIN-KDTV 59

Query: 62  QFAVRCDELILDDR------RVSVTGLRDYHTVLGAREDYRGLKSHETIQTWR-----EY 110
           + A++    I                ++  +  L  +        +  +   R     E 
Sbjct: 60  KIALKIKNPIQKTNIALNLIDTKRDKIKKSNISLDNKSIKSIKIYNVNLIPNRTQIRFEM 119

Query: 111 LCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQ 163
           L +  + + + LT        +      K  YT  LG          ++G  +
Sbjct: 120 LKNPKYRLYVHLTDEKLYSKLKKLLEQHKTVYTISLGLSELLANFE-YMGEFE 171


>UniRef50_B8CYA3 CRISPR-associated protein Cas5 n=1 Tax=Halothermothrix orenii H 168
           RepID=B8CYA3_HALOH
          Length = 238

 Score =  110 bits (275), Expect = 4e-23,   Method: Composition-based stats.
 Identities = 26/205 (12%), Positives = 63/205 (30%), Gaps = 17/205 (8%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
             L+ ++ G +  + +     +  T + P R+ L+G++ + L   RD    L +  ++ +
Sbjct: 5   QVLVFKIKGKIAHFKKYYSNKSSLTYKIPPRTVLMGIVASILEKPRDSYYELLSPQQA-K 63

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWL 122
           F V+ +               D        +    L     + +++           ++ 
Sbjct: 64  FGVKIESESYTHFECMNYLKEDGGHTQVRLQL---LLPANNMLSYK-----------VFF 109

Query: 123 TPHATMVISELEKAVLKPR--YTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180
           T     ++ EL   +      Y  YLG+R    T             +    N + +   
Sbjct: 110 THQDESLLKELATKIKNKIYGYGIYLGQRQFRATAEFDDLIEDIDIIKDYTGNLKTLTYK 169

Query: 181 IYSEESVTGHHLKFTARDEPMITLP 205
              ++            + P+    
Sbjct: 170 DNIKKLNDTTTYNLILDNMPVSFKK 194


>UniRef50_B6IWM3 CRISPR-associated protein, CT1976 family n=1 Tax=Rhodospirillum
           centenum SW RepID=B6IWM3_RHOCS
          Length = 280

 Score =  110 bits (274), Expect = 4e-23,   Method: Composition-based stats.
 Identities = 56/206 (27%), Positives = 82/206 (39%), Gaps = 31/206 (15%)

Query: 4   YLILRLAGPMQAWGQPT----FEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE 59
           +L   LA P  AWG  +        + T   P+RS L GLLGA LG++R   + L  LSE
Sbjct: 7   HLCFTLAAPYGAWGAASQSSATTAWKATELDPSRSALTGLLGAALGLER---AHLGRLSE 63

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYR---------------GLKSHETI 104
           +++FAVR       D +       DYHT+  A                    G K    +
Sbjct: 64  ALRFAVRTGIRPTRDPQP------DYHTISRAHRPEGREHWSRFEELRPALAGGKQEGAL 117

Query: 105 QTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQA 164
            + REY     +TVA+     A + +  L +A+  P +  Y GR++C L  P        
Sbjct: 118 LSRREYWSLGLWTVAVATLNPAGVPLDRLAQALRTPHWPLYAGRKACTLGLPPDPEVRTG 177

Query: 165 SDPQKALLNYEPVGGDIYSEESVTGH 190
             P   LL+Y         +  +   
Sbjct: 178 PGPLSVLLDYGW---PWQRKPGLDRP 200


>UniRef50_B1B9K0 Crispr-associated protein Cas5, tneap subtype n=1 Tax=Clostridium
           botulinum C str. Eklund RepID=B1B9K0_CLOBO
          Length = 244

 Score =  110 bits (274), Expect = 5e-23,   Method: Composition-based stats.
 Identities = 23/155 (14%), Positives = 53/155 (34%), Gaps = 7/155 (4%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              ++L++   +  + +PT    + T   P  S ++G++ A  G   D+   ++   +  
Sbjct: 1   MKAILLKVTQNLVNYKKPTSFQLKETYPLPPYSTVIGMVHAACGF--DEYKDMEVSIQGN 58

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
             +   D     +   +    +  H +    ED           +  E L D    + + 
Sbjct: 59  YHSKVNDLYTRYEFAGASYEDKR-HNIKLKGEDKYYGAMRG--VSTCELLVDVELLIHI- 114

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHP 156
             P    +I  + + +  P+    +GRR       
Sbjct: 115 -KPKDENLIQIIYQNLKYPKEYLSIGRREDIARIE 148


>UniRef50_A3XI99 Putative uncharacterized protein n=1 Tax=Leeuwenhoekiella
           blandensis MED217 RepID=A3XI99_9FLAO
          Length = 243

 Score =  109 bits (272), Expect = 7e-23,   Method: Composition-based stats.
 Identities = 33/231 (14%), Positives = 68/231 (29%), Gaps = 23/231 (9%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQ--RDDTSSLQALSE 59
               I+ +     ++  P F+    +   P  + ++G+ GA LG    R      ++  E
Sbjct: 1   MKNFIIEIQCQTASFRNPDFQNFHKSLELPPPTTVIGIAGAALGYSPLRAQEFFDESKFE 60

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
              +     +     +      +RD                 +     RE+L   +F +A
Sbjct: 61  IGIYGTYLGKCKDTWKYNKG--IRDM---------RLYDPGLDGSIIQREFLIFPTFIIA 109

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLT---HPLFLGTCQASDPQKALLNYEP 176
              +      + +L KA   P Y   +G      +     + L   +A   +   +  + 
Sbjct: 110 --FSSENIKAVEKLYKAFTSPVYALTMGNSDSLASIKNIEINLEISEADKIENCFVQGDV 167

Query: 177 VGGDIYSEESVTGHHLKFT----ARDEPMITL-PRQFASREWYVIKGGMDV 222
           V   +    S       +T      D P+       +  R    I     +
Sbjct: 168 VNEVMSLANSGNFEFSIYTNDTLTYDLPIRFEYENDYGRRTVSKIDTYSLI 218


>UniRef50_C5CFB1 CRISPR-associated protein Cas5, Hmari subtype n=1 Tax=Kosmotoga
           olearia TBF 19.5.1 RepID=C5CFB1_KOSOT
          Length = 236

 Score =  108 bits (271), Expect = 1e-22,   Method: Composition-based stats.
 Identities = 33/174 (18%), Positives = 62/174 (35%), Gaps = 25/174 (14%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQ----RDDTSSLQAL 57
              L+L ++     + +P    +  T   P R+ +LG++G+ LGI          S    
Sbjct: 1   MKVLVLDISSDYAHFRKPYTTTSALTYSIPPRTAVLGIIGSILGISSGGFGKSEHSKFFE 60

Query: 58  SESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFT 117
           + +V+  VR    I          L+  HT           K+  +I    E +    + 
Sbjct: 61  TNNVKTGVRLLTSIKKTTFN----LKYLHT-----------KNGGSILVPVECVVSPIYR 105

Query: 118 VALWLTPHATMVISELEKAVLK--PRYTPYLGRRSCPLTHPLFLGTCQASDPQK 169
           + +         +++LE  V      YTPYLG      +   ++G  +     +
Sbjct: 106 IYVS---GNEDFLAKLESVVKNKECYYTPYLGISEFLASVS-YVGFFEGKRVDE 155


>UniRef50_Q2RXJ5 CRISPR-associated protein, Cas5e family n=5 Tax=Proteobacteria
           RepID=Q2RXJ5_RHORT
          Length = 249

 Score =  108 bits (271), Expect = 1e-22,   Method: Composition-based stats.
 Identities = 49/204 (24%), Positives = 78/204 (38%), Gaps = 6/204 (2%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           LI+ L  P+ A+G    +    T  FP  S L GL    LG +R +    Q L + + FA
Sbjct: 7   LIVHLEAPLLAFGGVAIDNVGVTRDFPAASMLTGLFANALGWRRTEWERHQRLQDRLIFA 66

Query: 65  VRCDELILD-----DRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
            R +           +   ++      T  G  E   G       +  R+Y  DAS  VA
Sbjct: 67  ARRERENPTGVLTDTQNAKLSKTERGWTTWGEPEGRDGASYGAPHRRRRDYHGDASVVVA 126

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTC-QASDPQKALLNYEPVG 178
           L L       + +L  A+ +P    ++GR+SC  + PL       A+   +AL      G
Sbjct: 127 LRLDAAEEPALDDLAAALDRPARPLFIGRKSCVPSRPLRGKEFVVAATAYQALQALRSDG 186

Query: 179 GDIYSEESVTGHHLKFTARDEPMI 202
            D   + +       +   + P+ 
Sbjct: 187 NDRQRDGAAAERRAVWPVGEGPVD 210


>UniRef50_Q6NEQ9 Putative uncharacterized protein n=1 Tax=Corynebacterium
           diphtheriae RepID=Q6NEQ9_CORDI
          Length = 242

 Score =  108 bits (271), Expect = 1e-22,   Method: Composition-based stats.
 Identities = 47/202 (23%), Positives = 72/202 (35%), Gaps = 22/202 (10%)

Query: 1   MRSYLILRLAGPMQAW-GQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE 59
           M     +RL+GP+Q+W G         T   PT S L GLL   LG +R +  +      
Sbjct: 1   MIESAYIRLSGPLQSWAGSVVTGNIVRTEPRPTFSSLRGLLAGALGARRGEWPNWLD--- 57

Query: 60  SVQFAVRCDELILDDRRVSV--------TGLRDYHTVLGAREDYR------GLKSHETIQ 105
            V+F VR D   +               T  +      G + +              T  
Sbjct: 58  DVEFWVREDRKPIVVNEFQTINPLPEVETFRKRLLIAQGRKANSAKALTFTPDAQGGTSI 117

Query: 106 TWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQAS 165
             R YL D  + V +  + H    + E+E A   P +  YLGR++     P +LG   A 
Sbjct: 118 VNRTYLADGEYLVRVTSSTH----MDEIENAFSSPAFVTYLGRKAFYAEFPFYLGRGSAD 173

Query: 166 DPQKALLNYEPVGGDIYSEESV 187
             +K  + +         +  V
Sbjct: 174 AFEKIPVVHRNSDESKAQKSQV 195


>UniRef50_B8IJS9 CRISPR-associated protein Cas5 family n=1 Tax=Methylobacterium
           nodulans ORS 2060 RepID=B8IJS9_METNO
          Length = 253

 Score =  108 bits (269), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 51/244 (20%), Positives = 78/244 (31%), Gaps = 34/244 (13%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           MR +L+L L  P+QAWG    +   P   FP  + + GL+   LG  R D   L+AL E 
Sbjct: 1   MREHLLLLLEAPLQAWGGVLVDAYGPVDEFPAATLVGGLVANALGYDRADWQRLEALQER 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRD---YHTVLGAREDYRG--LKSHETIQTWREYLCDAS 115
           +                    L       T  G  E   G         + +R+Y  D  
Sbjct: 61  LVVGAAVLRRGSTITDNQNAKLEKGDVGWTTRGRPEGRGGGAEAYKSPHRRFRDYHADTL 120

Query: 116 FTVALWLTPHAT-MVISELEKAVLKPRYTPYLGRRSCPLTHPL-FLGTCQASDPQKAL-- 171
             VAL L P      +  +   +  P    +LGR+ C  +  + +    +A    KAL  
Sbjct: 121 ALVALRLDPEDEKPDLDAIAHTLEWPERPLFLGRKPCLPSRSIVWPERMRAETLLKALNL 180

Query: 172 -------------------------LNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPR 206
                                      +    G+  S   V     +    D P+    R
Sbjct: 181 GAAMLVAAESANPKLRLELDAGPWRARWPEREGNAPSSRLVEVCDDRDFRNDVPVGLRRR 240

Query: 207 QFAS 210
           +  +
Sbjct: 241 RVGT 244


>UniRef50_B1L2N4 Crispr-associated protein Cas5, hmari subtype n=3 Tax=Clostridium
           botulinum RepID=B1L2N4_CLOBM
          Length = 253

 Score =  107 bits (267), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 24/161 (14%), Positives = 59/161 (36%), Gaps = 7/161 (4%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRP-TGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
              +   L+GP   + +P        T     +  LLG+LG+ +G++  +          
Sbjct: 1   MEAIKFNLSGPTAFFKKPDVNSYAYFTYNNIHKIALLGILGSIIGLKGYNQQKSIDTYPE 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL-KSHETIQTWRE-YLCDASFTV 118
               ++  ++ +  +  +    + + T       Y            +RE +L + S+ +
Sbjct: 61  FYDKLKTLKISIVPKSKTGYFTKKFQTFTNNTGFYNIDINKRPCTLVYREQWLENVSWDI 120

Query: 119 ALWLTPH--ATMVISELEKAV--LKPRYTPYLGRRSCPLTH 155
            + L  +     ++++L+  +   K  + PYLG+       
Sbjct: 121 YILLDENSVDKKILNKLKDYLLNKKCHFIPYLGKNDHTADI 161


>UniRef50_C2GEY8 CRISPR-associated protein n=1 Tax=Corynebacterium glucuronolyticum
           ATCC 51866 RepID=C2GEY8_9CORY
          Length = 242

 Score =  107 bits (266), Expect = 4e-22,   Method: Composition-based stats.
 Identities = 48/183 (26%), Positives = 71/183 (38%), Gaps = 21/183 (11%)

Query: 1   MRSYLILRLAGPMQAW-GQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE 59
           M S   +RL+GP+Q+W GQ        T   PT +GL GLL   LG +RD+     +   
Sbjct: 1   MPSSTFIRLSGPIQSWAGQSVSGNFIRTNPIPTLTGLRGLLAGALGARRDEIPEWIS--- 57

Query: 60  SVQFAVRCDELILDDRRVSVTGLR----DYH---------TVLGAREDYRGLKSHETIQT 106
            V+F+VR D+           G R    D+               ++             
Sbjct: 58  KVRFSVREDQTGSFVDDFQTIGSREEEWDFRRRIAILQGMKARSIKQLSFKPAVGANAVV 117

Query: 107 WREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASD 166
            R YL +A F V +           E++ A   P +  YLGR++ P   P +LGT     
Sbjct: 118 RRTYLSEAEFIVRVT----DERHTEEIDHAFSSPVFATYLGRKAFPAAFPFYLGTGNEDV 173

Query: 167 PQK 169
             +
Sbjct: 174 LHQ 176


>UniRef50_C9RCY2 CRISPR-associated protein Cas5, Hmari subtype n=2
           Tax=Thermoanaerobacteraceae RepID=C9RCY2_AMMDK
          Length = 266

 Score =  106 bits (265), Expect = 5e-22,   Method: Composition-based stats.
 Identities = 36/227 (15%), Positives = 62/227 (27%), Gaps = 16/227 (7%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M +  +  L GP   + +     +  +  FP R+ L+G + A LG +RD       LSE+
Sbjct: 1   MVNVAVFDLVGPFAHFRKYYTNSSSLSYAFPPRTALMGTVAAVLGWERDSYYEKLGLSEA 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYL-----CDAS 115
            +FAV     +    +                   +      T       L         
Sbjct: 61  -RFAVVIKVPVRRLIQTVNYIRTK---EEDLNRLRKLEAVKGTQVPLELLLPGGTASSLC 116

Query: 116 FTVALWLTPHATMVISELEKAVL--KPRYTPYLGRRSCPLTHPL--FLGTCQASDPQKAL 171
           F V          V  EL + +   +  +  YLG         L  F    +     + +
Sbjct: 117 FRVY--FAHRDDQVTRELAERLAAGRSYFPLYLGLTEFIAQARLVDFKPPDEIIPAGQEV 174

Query: 172 LNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKG 218
             +  +  D      + G          P      +        I  
Sbjct: 175 ELHSVLAADYLRRPVLRGEVA-LNRERAPQSFGAGRKLMPPRSYIYE 220


>UniRef50_A8F3P0 CRISPR-associated protein Cas5, Hmari subtype n=1 Tax=Thermotoga
           lettingae TMO RepID=A8F3P0_THELT
          Length = 230

 Score =  106 bits (265), Expect = 6e-22,   Method: Composition-based stats.
 Identities = 28/180 (15%), Positives = 61/180 (33%), Gaps = 22/180 (12%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRD--DTSSLQALSE 59
              ++  + G    + +     +  +  FP R+ + GLLGA +GIQ +    S    + +
Sbjct: 1   MKVIVFDVKGKYALFRRNYTTSSSTSYNFPPRTSICGLLGAIMGIQNEATQFSKHLRIFD 60

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
           +   A+R    I               T +G          ++  Q   E + +  + + 
Sbjct: 61  NAHIALRVLVPIRK-------------TTMGVNYAETKSGKNQRTQIILELIKEPVYRIY 107

Query: 120 LWLTPHATMVISELEKAVLK--PRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPV 177
           +           +L   +      +TPYLG+          +G  +A      ++ +  +
Sbjct: 108 VS----EFSQFDQLRNHLENNTCVFTPYLGQAQFIAKIS-HVGVFEAKSVFPPVVVHSVL 162


>UniRef50_C5VUI7 Crispr-associated protein Cas5, hmari subtype n=1 Tax=Clostridium
           phage D-1873 RepID=C5VUI7_9VIRU
          Length = 237

 Score =  106 bits (265), Expect = 6e-22,   Method: Composition-based stats.
 Identities = 25/215 (11%), Positives = 62/215 (28%), Gaps = 23/215 (10%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGT-RPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
                  ++G    + +P        +     +  +LGLLGA +G+ +D         + 
Sbjct: 1   MRGFKFNVSGKTAFFKKPDINQYINFSYSHIHKPCILGLLGAIIGLDKDSYY---NTLKH 57

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWRE-YLCDASFTVA 119
           ++ ++                 +         +      ++ T    RE +L + S+ + 
Sbjct: 58  LKISI---------VPNKPYFNKSIQVYNNTTKFANKSLNNPTTLNVREQWLENVSWDIY 108

Query: 120 LWLTPHATMVISELEKAVL--KPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPV 177
           +       ++  ++ + +   K  Y  Y GR+    +            P+         
Sbjct: 109 IIAEDKD-VIYDKIYEYIRGFKSVYNIYFGRKEHITSIMFIEDFDIQDVPEDVFQINGLF 167

Query: 178 GGDIYSEE------SVTGHHLKFTARDEPMITLPR 206
             +I +E               F     P+    +
Sbjct: 168 PYNIINEIGTNKSDESKDKVSYFLKETMPIRYNNK 202


>UniRef50_A4J1X9 CRISPR-associated protein Cas5, Hmari subtype n=1
           Tax=Desulfotomaculum reducens MI-1 RepID=A4J1X9_DESRM
          Length = 242

 Score =  105 bits (263), Expect = 8e-22,   Method: Composition-based stats.
 Identities = 36/227 (15%), Positives = 75/227 (33%), Gaps = 17/227 (7%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSS-LQALSE 59
           M   +  RL+G    + +     +  +   P R+ LLG+LGA LG+++D     L+ L  
Sbjct: 1   MMKLIAFRLSGRFGHFLRAEAGTSALSYPVPPRTVLLGILGAVLGLEKDLPQELLEPLHI 60

Query: 60  SVQFAVRCDELIL-DDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV 118
           ++   V          R+     L     V   ++  +  K        +E+L + ++T+
Sbjct: 61  ALAGPVPQSHWHKAKLRKDPPEAL--PQVVKNNQKQEKTTKPEMATLITQEWLFNPAYTI 118

Query: 119 ALWLTPHATMVISELEKAVLK--PRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEP 176
            + L         +LE+ + +    + P LG                   P+ +      
Sbjct: 119 WVALP---EPYHQQLEQRLKERCWHFQPCLGLSEMMADIEYLGTLMAEKLPRGSYPVTSI 175

Query: 177 VGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVS 223
           +  +    +            D+ +   P +   R     +     S
Sbjct: 176 IPQEQAKLDL-------TQVYDQELALQPLR-MPRTVTSSRVFGHSS 214


>UniRef50_C7NNV3 CRISPR-associated protein Cas5, Hmari subtype n=3
           Tax=Halobacteriaceae RepID=C7NNV3_HALUD
          Length = 264

 Score =  105 bits (263), Expect = 8e-22,   Method: Composition-based stats.
 Identities = 40/215 (18%), Positives = 66/215 (30%), Gaps = 21/215 (9%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
             L   + GP   + +      + T R   R+ + GL+ A LGI RD    L     S  
Sbjct: 19  RCLSFEIRGPWGHFRRVEGNVVKQTYRIVPRTTVAGLIAAVLGIDRDGYYDLFGPEVS-A 77

Query: 63  FAVRCDELILDDRRVSVTGLR---DYHTVLGAREDYRGLKSHETIQTWR---EYLCDASF 116
            A++  E +        T      D  T L  R        + T    +   E L D ++
Sbjct: 78  IAIQPVEELRTVNMPMNTLSTAAGDL-TSLNPRGKISIKLPNPTKLRQQHNYEVLVDPAY 136

Query: 117 TVALWLTPHATMVISELEKAVL--KPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNY 174
            + + L         +L + +   K  Y P LG               +     +  +  
Sbjct: 137 RIDVALADDER--YEQLRETLAAGKSHYVPSLGLSEYLA---------EIDYLGEFDVKP 185

Query: 175 EPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFA 209
            P  G I  + +V           E    + +  A
Sbjct: 186 GPASGTIAVDSAVPDAMDDVVLDPETRCQIEQSPA 220


>UniRef50_C6QNG6 CRISPR-associated protein Cas5, Hmari subtype n=1 Tax=Geobacillus
           sp. Y4.1MC1 RepID=C6QNG6_9BACI
          Length = 244

 Score =  105 bits (263), Expect = 1e-21,   Method: Composition-based stats.
 Identities = 30/230 (13%), Positives = 66/230 (28%), Gaps = 28/230 (12%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              LI  L G M  + +     +  +  FP R+ ++G++   LG++RD    + +  +  
Sbjct: 1   MKMLIFDLIGKMGHFRKIDTNSSSLSYAFPPRTTIVGMIAGILGMERDSYYEVFS-PDQC 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYL-----CDASF 116
           Q A+     I    +                + +       T       L      +  +
Sbjct: 60  QIAISVRTPIRKVMQTVNYMFVK-------SKAHLNNSGGHTQIPLEFVLPGGEEANLRY 112

Query: 117 TVALWLTPHATMVISELEKAVL--KPRYTPYLGRRSCP------LTHPLFLGTCQASDPQ 168
            +    +     V   +++ +   +  Y PYLG                 L       P 
Sbjct: 113 RIY--FSHSDRSVYESVKERIQSGRYVYPPYLGLSELLGQLQWVAEAEGMLKESNDLVPI 170

Query: 169 KALLNYEPVGGDIYSEESVTGHHLKFTARDEPMIT-LPRQFASREWYVIK 217
            +++       D+           +F            R     ++Y+ +
Sbjct: 171 HSVVRIP----DLRERSIQFSRDTRFLKEFMTRQFTNERMIQETDYYLFE 216


>UniRef50_C8VZL1 CRISPR-associated protein Cas5 n=1 Tax=Desulfotomaculum acetoxidans
           DSM 771 RepID=C8VZL1_DESAS
          Length = 253

 Score =  105 bits (262), Expect = 1e-21,   Method: Composition-based stats.
 Identities = 35/232 (15%), Positives = 66/232 (28%), Gaps = 35/232 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              +   L G M  + +     +  +   P R+ L+G++   LG +RD    + +L+ S 
Sbjct: 1   MKIISFHLRGKMAHFRRYYANSSALSYSIPPRTTLIGIVAGLLGWERDKYYEIFSLN-SC 59

Query: 62  QFAV----RCDELILDDRRVSVTGLRDY-----HTVLGAREDYRGLKSHETIQTWREYLC 112
           + AV       + +     + +    D      H    A E          I  ++ +L 
Sbjct: 60  KVAVASCAPVKKCMQKLNLLMIKKAGDLNGSAEHHSQTATELIIPQNIRTGIIDYQVWL- 118

Query: 113 DASFTVALWLTPHATMVISELEKAVL-KPRYTPYLGRRSCPLTHPLFLGTCQASDPQKAL 171
                           ++  L K +  + R    LG     L     LG        + +
Sbjct: 119 ----------HHRDNKIMDMLGKLLQLEGRGYKSLGIS-LALGTVFNLGWVDDGCIIEGV 167

Query: 172 LNYEPVGGDIYSEESVTG-----------HHLKFTARDEPMITL-PRQFASR 211
              +     I S   V                +    + P+     R    R
Sbjct: 168 EKEKSNDLSIASVIPVKKLIGIQTERMGADEYRLVKEEIPLEFDSQRHITER 219


>UniRef50_O27159 Putative uncharacterized protein n=1 Tax=Methanothermobacter
           thermautotrophicus str. Delta H RepID=O27159_METTH
          Length = 269

 Score =  105 bits (261), Expect = 1e-21,   Method: Composition-based stats.
 Identities = 31/217 (14%), Positives = 63/217 (29%), Gaps = 15/217 (6%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L + +  P   +  P       T     +S + G+L    G  R     +  +S S+
Sbjct: 1   METLAVEIFQPFAQFRNPFTFDYAQTYPLSPKSTVTGMLQNATG--RYYDQDISEISVSI 58

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHT-----VLGAREDYRGLKSHETIQTWREYLCDASF 116
              +           +       YH             Y   K  +   ++++ L +  +
Sbjct: 59  H-GLFESTFWNYQSFIVGDIALKYHHNKLKLWNKGYPLYSVNKKSQRSPSYQQELFNGHY 117

Query: 117 TVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGT-CQASDPQKALLNYE 175
            + L        +I E+  ++ KP     LGR           G        ++ +    
Sbjct: 118 YIFLR---GDDDIIEEVCDSLRKPTKPLSLGRSE---DIIFIRGIHRDFEVIEREVKKNL 171

Query: 176 PVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASRE 212
            +    Y + S    H        P+ ++P +   R 
Sbjct: 172 WMTYPTYIKLSNGKTHFPIRNERFPVYSIPERVIFRN 208


>UniRef50_C9M4F0 Putative uncharacterized protein n=1 Tax=Lactobacillus helveticus
           DSM 20075 RepID=C9M4F0_LACHE
          Length = 237

 Score =  104 bits (260), Expect = 2e-21,   Method: Composition-based stats.
 Identities = 22/194 (11%), Positives = 59/194 (30%), Gaps = 11/194 (5%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              + ++L      +  P   G R +   P  S ++G++         +   ++   +  
Sbjct: 1   MKVIRVKLHQETANYRVPASHGFRESYPLPPISTVIGMVHYLC--DFHEYHPMKVSVQGS 58

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
             +   D     + +  +      H             S        + L D +  + + 
Sbjct: 59  YVSTTSDFFTRYEFKNGLKFDPGRH----QLNAEGYGISRG--IGHVQLLYDVNLILHI- 111

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTH-PLFLGTCQASDPQKALLNYEPVGGD 180
             P     + ++  A+  PR  P LGRR   +    + +   +  D    + +   +  +
Sbjct: 112 -KPDDENELEDIYNALKYPREFPNLGRREDLVNFEEVKIVDVEKKDEDLTVNHGAYIPVE 170

Query: 181 IYSEESVTGHHLKF 194
           +     +    + +
Sbjct: 171 MSENIGLENEGIGY 184


>UniRef50_A7VC52 Putative uncharacterized protein n=1 Tax=Clostridium sp. L2-50
           RepID=A7VC52_9CLOT
          Length = 238

 Score =  104 bits (260), Expect = 2e-21,   Method: Composition-based stats.
 Identities = 23/174 (13%), Positives = 51/174 (29%), Gaps = 8/174 (4%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M   + +     +  + +P+    + +   P  S ++G++ A  G   D    +Q   + 
Sbjct: 4   MERAIRIDCFQNLANYRKPSSFIIKESYPLPPYSTVIGMIHAISGF--DSYHKMQVSIQG 61

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
                  +       +         H +    ED              E +CD    + +
Sbjct: 62  ENAGSVSELYTRYSFKFDTKYEEGRHQLCIKGEDKDYGVFKG--IAHVELICDNRMVLHI 119

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNY 174
                      ++ +A+  P   P LGR    L     +   +    + A +  
Sbjct: 120 I---PEEEDFDKIYQALKCPIIYPSLGRYEDLLDIQ-NVEIVELQKVESATIRN 169


>UniRef50_A0B6V6 CRISPR-associated protein Cas5, Hmari subtype n=1 Tax=Methanosaeta
           thermophila PT RepID=A0B6V6_METTP
          Length = 233

 Score =  103 bits (258), Expect = 3e-21,   Method: Composition-based stats.
 Identities = 32/220 (14%), Positives = 59/220 (26%), Gaps = 19/220 (8%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
           S L+  + G    + +     +  T  FP R+ + G++GA  G+ ++      +  ++  
Sbjct: 4   SVLVFDVWGDYAHFRKIYTTSSPLTYSFPPRTAISGIIGAIAGLSKESYFRYFSRDKA-S 62

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWL 122
              R  E +   R                       + H   Q   E+L D  F + L  
Sbjct: 63  IGCRILEPVKKVRVGENLI----------DTKRSMHRIHNRTQVRFEFLKDPRFRIYLS- 111

Query: 123 TPHATMVISELEKAVL--KPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180
                    +L   +   +  YTP LG                             V   
Sbjct: 112 -HSDDRFSRDLRDMLEDHRCVYTPCLGLSQLVCNFKFVGELGLRRCGDGLQEINSVVPLK 170

Query: 181 IYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGM 220
              E        ++ +   P +        RE       +
Sbjct: 171 SLLESPEFEEGREYFSEIMPCVIGEG----REVTDYSEVL 206


>UniRef50_B0VIK7 Putative uncharacterized protein n=1 Tax=Candidatus Cloacamonas
           acidaminovorans RepID=B0VIK7_9BACT
          Length = 259

 Score =  103 bits (257), Expect = 4e-21,   Method: Composition-based stats.
 Identities = 36/210 (17%), Positives = 65/210 (30%), Gaps = 17/210 (8%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
             L L+L+G    + +     +  T   P R+ + GLL + L I+RD   +L + S+ + 
Sbjct: 9   RILELKLSGKFAHFRKFYTNASSLTYLIPPRTAICGLLASILQIERDCYYNLMS-SDKLG 67

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYL-----CDASFT 117
            A+     I   +          +      ++          Q   E L      +  + 
Sbjct: 68  IAISLVPNIYYHKVFQT-----LNYAQDKSKNIPINDLSAHKQCRLELLKAQGSKNLEWI 122

Query: 118 VALWLTPHATMVISELEKAV--LKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYE 175
           + L          +ELE  +      Y  YLG+R       L     Q     K +   +
Sbjct: 123 LYLCFNSAEENNFAELEHKIKEKNFGYGLYLGQRQFIAYLELIRTYSQGE--FKPISESD 180

Query: 176 PVGGDIYSEESVT--GHHLKFTARDEPMIT 203
            +   I  E   +             P+  
Sbjct: 181 YLDSAIERELIDSIISQDCDLIMERMPLEQ 210


>UniRef50_C5D4M6 CRISPR-associated protein Cas5, Hmari subtype n=1 Tax=Geobacillus
           sp. WCH70 RepID=C5D4M6_GEOSW
          Length = 245

 Score =  103 bits (257), Expect = 4e-21,   Method: Composition-based stats.
 Identities = 27/224 (12%), Positives = 65/224 (29%), Gaps = 17/224 (7%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQAL-SES 60
            + L+  +      + +     +  T      +   G+LGA +G+ +++   L+ +  E+
Sbjct: 1   MNVLVFDIRADFGHFRKIYSTSSPLTYSIIPPTSFFGILGAIIGLGKEENEYLRYVNHET 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           V  A+R    +   R          +  +  +            Q   E+L    F   +
Sbjct: 61  VNMAIRVMSPVRKMRIGLNHVNTKGNVWVPKQRRE-----GARTQIRTEFLRFPYFRCYV 115

Query: 121 WLTPHATMVISELEKAV--LKPRYTPYLGRRSCPLTHPL--FLGTCQASDPQKALLNYEP 176
            +      +  +L + V   +  YT  +G   C               ++  +A+     
Sbjct: 116 HV--KEQSLFQQLIEYVQQHRSVYTVCMGLSECIADVRYVSLEEFRLVNNNAEAVSIASV 173

Query: 177 VGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGM 220
           +     +   +         R E           R     +  +
Sbjct: 174 IPEKYVTSLCIESGKEY---RKERFAFQID--TERIVSDYEEVL 212


>UniRef50_B0ABR7 Putative uncharacterized protein n=1 Tax=Clostridium bartlettii DSM
           16795 RepID=B0ABR7_9CLOT
          Length = 229

 Score =  103 bits (257), Expect = 4e-21,   Method: Composition-based stats.
 Identities = 28/224 (12%), Positives = 66/224 (29%), Gaps = 21/224 (9%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L+ ++ G    + +     +  T        + GL+GA LGI R     L   ++ +
Sbjct: 6   MKCLVFKVRGDYARFRKSYTTTSALTYLLIHPVAVRGLIGAMLGIDR---EKLYEKTKDI 62

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           + A++    +  D +        ++ V     D           +  E+L +  + + + 
Sbjct: 63  EVAIQVVNQVRKDMQS-------FNLVNMKANDKI-----FRFPSNVEFLRNVEYRIFIK 110

Query: 122 LTPHATMVISELEKAVLKP--RYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGG 179
                   + E++  + +    +TPYLG          + G                   
Sbjct: 111 A---EDKTLYEIDNCIKQGEYIFTPYLGSSEHIAKIE-YEGIYNCEKLNAGNYKVISAVS 166

Query: 180 DIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVS 223
              ++       +     + P      +       VI    + +
Sbjct: 167 LEENKIYFGDSDIILMTDNIPTRRDIDREYIEYKKVIFATNENT 210


>UniRef50_Q0AW00 CRISPR-associated protein, Cas5h family n=2 Tax=Clostridiales
           RepID=Q0AW00_SYNWW
          Length = 246

 Score =  103 bits (257), Expect = 5e-21,   Method: Composition-based stats.
 Identities = 34/158 (21%), Positives = 55/158 (34%), Gaps = 6/158 (3%)

Query: 2   RSYLILRLAGPMQAWGQPTFE-GTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
              L   L+GP+  + QP        T     +  LLGLLGA +G+     + L    E 
Sbjct: 1   MKSLRFTLSGPLACFRQPDVNAKVYFTYNNIHKVALLGLLGAVIGLSGYRNADLYGQGEK 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGARE---DYRGLKSHETIQTWREYLCDASFT 117
           +          L    V       +   +        Y   +    +Q   ++L + ++T
Sbjct: 61  LYPEFYEVLSPLLVSVVPNVKNGYFSKKIQYFNNSVGYASKEEGGNLQVREQWLENPNWT 120

Query: 118 VALWLTPHATMVISELEKAVLK--PRYTPYLGRRSCPL 153
           V L        +  +L   +L+    Y PYLGR   P 
Sbjct: 121 VFLAQHKLDASIWDKLCDYMLRGQCVYIPYLGRNDFPA 158


>UniRef50_A0RNQ4 Crispr-associated protein Cas5, hmari subtype n=2 Tax=Campylobacter
           RepID=A0RNQ4_CAMFF
          Length = 253

 Score =  103 bits (256), Expect = 5e-21,   Method: Composition-based stats.
 Identities = 25/227 (11%), Positives = 65/227 (28%), Gaps = 21/227 (9%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRP-TGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
              +  +L+G    + +P        T     +  LLGLLGA +G++     + +   + 
Sbjct: 1   MRAVSFKLSGKFAHFKKPDVNEYAYFTYNNIPKPTLLGLLGAIIGLKGYAQKTYKDKKDK 60

Query: 61  VQF--------------AVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQT 106
                             ++  ++ +          +           Y   +    +  
Sbjct: 61  KSLFNNENSSNEPEFYERLKHLKICIIPLVKYGRFSKKIQIFNNGV-GYASGEDGGNLIV 119

Query: 107 WREYLCDASFTVALWLTPHATMVISELEKAV--LKPRYTPYLGRRSCPLTHPLFLGTCQA 164
             ++L + S+ + +     A      + + +   K ++ PYLG+               A
Sbjct: 120 REQWLENPSWQILIEDDGSAE--FETVSRYLFDKKAKFIPYLGKNDHFADISEVEKIDLA 177

Query: 165 SDPQKALLNYEPVGGDIYSEESVTGHHLKFTARD-EPMITLPRQFAS 210
              +  +        D+  +       + +   +  P+      F  
Sbjct: 178 ESKKDRISIKSLFLDDLAEQVDDPDDEISYLFNEFYPISFNELMFYE 224


>UniRef50_A4XGC7 CRISPR-associated protein Cas5 family n=1 Tax=Caldicellulosiruptor
           saccharolyticus DSM 8903 RepID=A4XGC7_CALS8
          Length = 275

 Score =  103 bits (256), Expect = 6e-21,   Method: Composition-based stats.
 Identities = 31/240 (12%), Positives = 72/240 (30%), Gaps = 24/240 (10%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQ----------RDDTSS 53
            L +++  P   +  P     R T   P  S +LGL+   LGI+          +D+ + 
Sbjct: 10  ALKIKIYQPQAHFRIPFSYQRRHTYPIPPYSTVLGLIANILGIKNLPGQEEPCVKDNCNC 69

Query: 54  LQALSESVQFAV------RCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTW 107
           L    + ++  V      + +E        + + +  + ++               +   
Sbjct: 70  LYHKLKQIKIGVCGNFETKVEEYFWLRNLKAESHIGRFGSITNRYVGGHIEHIGGQMPCI 129

Query: 108 REYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPY---LGRRSC-PLTHPLFLGTCQ 163
            + L +A   + L         +  ++ +   P        LGR     +   +      
Sbjct: 130 VDVLHNARILIYL--YHCDKEFLEVIKSSFENPVNKTSVMHLGRAEDWIVIEDISYVNLI 187

Query: 164 ASDPQKALLNYEPVGGDIY-SEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDV 222
                    N+  V   ++  + +     +   A +        Q   R +  IK  ++ 
Sbjct: 188 IDKINGNYKNFFWVPEKVFGFDGNFDFKKVNGLAYNM-TSFYKIQNGVRNFRCIKAKLNN 246


>UniRef50_C9RW51 CRISPR-associated protein Cas5, Hmari subtype n=2 Tax=Geobacillus
           RepID=C9RW51_GEOSY
          Length = 247

 Score =  103 bits (256), Expect = 6e-21,   Method: Composition-based stats.
 Identities = 34/224 (15%), Positives = 62/224 (27%), Gaps = 14/224 (6%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQAL-SES 60
            + L+  +      + Q     +  T  F   +   GLLGA  G+ +++   L+    ++
Sbjct: 1   MNVLVFDIRADFGHFRQLYSTSSPLTHSFIPPTAFFGLLGAITGVGKEENEYLRVFNHKT 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
              A+R    +   R          +  +  +            Q   E+L    F   +
Sbjct: 61  TNMAIRLMGPVRKTRVGINYVNTKGNIWVPKQRRE-----GARTQIRVEFLRFPHFRCYV 115

Query: 121 WLTPHAT--MVISELEKAVLKPRYTPYLGRRSCPLTHPLFL---GTCQASDPQKALLNYE 175
            +  H     +I  + +   K  YTP LG   C                   +K +    
Sbjct: 116 SMNDHERFSYLIDLVRQH--KSVYTPCLGLSECLADVQFVAMEDFRFVQGAERKTVSICS 173

Query: 176 PVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGG 219
            +         V                 P +  SR   VI   
Sbjct: 174 VLPRKDVQVLEVEEGKEYR-KERVAWEMDPERVVSRYEEVIFEA 216


>UniRef50_C9L3W3 CRISPR-associated protein Cas5, Tneap subtype n=2 Tax=Clostridiales
           RepID=C9L3W3_RUMHA
          Length = 241

 Score =  101 bits (252), Expect = 2e-20,   Method: Composition-based stats.
 Identities = 28/200 (14%), Positives = 57/200 (28%), Gaps = 16/200 (8%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M   + L+    +  + +P+    + T   P  S +LG++ A              LS  
Sbjct: 1   MEKAIRLQCFQNLANYRKPSSFIIKETFPLPPYSTVLGMIHAACEFT---EFHPMKLSIQ 57

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
              A    EL       S +   +    +  ++               E +C+    + +
Sbjct: 58  GTNAGTISELYTRYSFSSGSKYEEGRHQICIKDKENYGIFKG--IANVELVCNNRMVIHI 115

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEP-VGG 179
                      ++ +++  P     LGR    L         ++ D        E  V  
Sbjct: 116 VPGEED---FQKVYESLKNPPKYLSLGRYEDILDI-------ESVDIVNIFQEEEVTVKR 165

Query: 180 DIYSEESVTGHHLKFTARDE 199
           DIY          +    ++
Sbjct: 166 DIYIPVDYETEEGEKLLENQ 185


>UniRef50_A8UUT1 Putative uncharacterized protein n=1 Tax=Hydrogenivirga sp.
           128-5-R1-1 RepID=A8UUT1_9AQUI
          Length = 253

 Score =  100 bits (250), Expect = 3e-20,   Method: Composition-based stats.
 Identities = 27/230 (11%), Positives = 61/230 (26%), Gaps = 20/230 (8%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L   L G    + +     +  +  FP    + G++GA +G  +++       ++ +
Sbjct: 1   MKVLSFSLFGDFAHFRKFYTTSSPLSFPFPPPPTIRGIIGAIMGFSKEEY---LDKTKGI 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHE-----TIQTWREYLCDASF 116
              V     +   R           +           +  +       Q   E++ D  +
Sbjct: 58  SVGVSLKAPLKKVRMGLNLIFTKG-SSGKFDPTLVPWRKGDVNKTLRTQIKAEFIKDPIY 116

Query: 117 TVALWLTPHATMVISELEKAVL--KPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNY 174
            + L         I EL + +   +  YT  LG            G  + +    +    
Sbjct: 117 RIYLSA---DEDFIEELAELLKEHRSYYTVSLGLSELIADFSF-EGIYEGNKINISARVD 172

Query: 175 EPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVSQ 224
             V      E  +     +      P          R+    +  +   +
Sbjct: 173 SVVSTKFVQEIDLERPQ-RIGKERIPAD----MCTDRKVLRYEDVIFNME 217


>UniRef50_C7P9L3 CRISPR-associated protein Cas5 n=2 Tax=Methanocaldococcus
           RepID=C7P9L3_METFA
          Length = 258

 Score =  100 bits (249), Expect = 3e-20,   Method: Composition-based stats.
 Identities = 26/222 (11%), Positives = 60/222 (27%), Gaps = 34/222 (15%)

Query: 2   RSYLILRLAGP-MQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
              L  R  G    ++ +P       T + P  + + GL+   LG+ RD           
Sbjct: 1   MWGLKFRCEGIYFVSFRKPVTTSLSLTYKLPPFTAIRGLIANALGMPRDSFEIQNWFKIG 60

Query: 61  VQFAVRCDELILDDRRVSVTGLR--------DYHTVLGAREDYRGLKSHETIQ------- 105
           ++   + +      + + +   +         +  +  ++         E +        
Sbjct: 61  MRVEGKIEIGREMAKFLKMISRKSCYRCENCRFEKIADSKPKKCPNCGKENLVKVEKMIY 120

Query: 106 --------TWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPL 157
                     RE+L    + + L         I ++  A+  P    YLG     +   +
Sbjct: 121 ERAFPSSPMHREFLIMPKYWIYLV---GEEKKIKKIYYALKSPERPLYLGTSDDLVDIEV 177

Query: 158 F-------LGTCQASDPQKALLNYEPVGGDIYSEESVTGHHL 192
           F       +   + +     +     +    Y    V     
Sbjct: 178 FKPVKVKEVEENEINSILDGIHENCILEKLPYRFIPVKDKKG 219


>UniRef50_A5N0X1 Putative uncharacterized protein n=2 Tax=Clostridium kluyveri
           RepID=A5N0X1_CLOK5
          Length = 246

 Score =  100 bits (249), Expect = 4e-20,   Method: Composition-based stats.
 Identities = 27/218 (12%), Positives = 67/218 (30%), Gaps = 15/218 (6%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRP-TGRFPTRSGLLGLLGACLGIQRDDTSS---LQAL 57
              +  +L+G    + +P        T     +  LLG++G+ LG+   ++ S      +
Sbjct: 1   MKAVRFKLSGRTAFFKKPDVNTYYYFTYGNIHKIALLGIIGSVLGLPGYNSQSRDFKNNI 60

Query: 58  SESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFT 117
                  ++  ++ +          +   T   +   Y  L++   +    ++L +  + 
Sbjct: 61  YPEFYNRLKDSKVAVVMLNHQGYITKKIQTFNNSV-GYASLEAGGNLVVKEQWLQEPKWM 119

Query: 118 VALWLTPHATMVISELEKAV--LKPRYTPYLGRRSCPLTH----PLFLGTCQASDPQKAL 171
           V + +      +  +    +   K  + PYLG+            + L   +      +L
Sbjct: 120 VYVKVD----EITEKFAHMLLHKKAIFLPYLGKNDHFADITEIKEVELEKSENYIKINSL 175

Query: 172 LNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFA 209
                   + Y EE               +     Q+ 
Sbjct: 176 FESRYFQVEKYQEEEDDTAWKYMEYLPVELDEELNQYR 213


>UniRef50_B5YIV3 CRISPR-associated protein Cas5 n=1 Tax=Thermodesulfovibrio
           yellowstonii DSM 11347 RepID=B5YIV3_THEYD
          Length = 239

 Score =  100 bits (248), Expect = 4e-20,   Method: Composition-based stats.
 Identities = 29/230 (12%), Positives = 70/230 (30%), Gaps = 21/230 (9%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              + ++L   M  + +    G   T   PT S + G+  + L + +     + ++  + 
Sbjct: 1   MKAVRIKLYQNMVNYRKELSYGYVQTYPLPTPSMVKGMAHSLLNLNKYHNLKI-SIQGNY 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
              V   + +    RV     R++      R    G +       + + + D    + + 
Sbjct: 60  ASVVTNMQKVYKFDRVRDDKKREF-IDPRPRIYAGGQRVLNQGIMFVDEIVDMELILHIS 118

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYE------ 175
                  +  +L +A+ +   T  LGR              + +     L   +      
Sbjct: 119 F--DDEGLNDKLLEALKQ--KTVILGRNEDIARVDF-----EDTSLVDILSFSDEYRLPY 169

Query: 176 --PVGGDIYSEESVTGHHLKFTARDEPM-ITLPRQFASREWYVIKGGMDV 222
              +  ++  +E + G   +     EP+     ++   R    I      
Sbjct: 170 NIYLAPELCKKEQLEGTCYRLPFYYEPVNSFTDKRIF-RYVNAIYIAKGN 218


>UniRef50_B7R550 CRISPR-associated protein Cas5 n=1 Tax=Thermococcus sp. AM4
           RepID=B7R550_9EURY
          Length = 275

 Score =  100 bits (248), Expect = 5e-20,   Method: Composition-based stats.
 Identities = 26/203 (12%), Positives = 58/203 (28%), Gaps = 19/203 (9%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
             L++ L  P   +  P       T   P +S ++G+L   L               +++
Sbjct: 4   KTLLIELFQPFAQYRNPFTFYYAQTYPLPPKSTIIGMLQNALN-DWYGNERGIDEWWNLR 62

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL-----------KSHETIQTWREYL 111
            +V      +      +         +        L            + +     ++ L
Sbjct: 63  VSVHGGFESVFWNYQQLIKATKTGISIVRFRGKPTLWNQKLPLYGFPVTSQRSPVLQQEL 122

Query: 112 CDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRS---CPLTHPLFLGTCQASDPQ 168
            +    + L         +SE+++A+ +PR    LGR      P       G    +   
Sbjct: 123 FNGWLYILL---KGEEEFLSEIKEALERPRKVISLGRSEDVVFPRRAEFIEGKKDEAREI 179

Query: 169 K-ALLNYEPVGGDIYSEESVTGH 190
                 Y  V  ++  ++    +
Sbjct: 180 GIKYPTYVRVPIEMLRKKEYPTY 202


>UniRef50_UPI0000F51765 hypothetical protein Faci_00030 n=1 Tax=Ferroplasma acidarmanus
           fer1 RepID=UPI0000F51765
          Length = 237

 Score = 99.7 bits (247), Expect = 6e-20,   Method: Composition-based stats.
 Identities = 21/207 (10%), Positives = 60/207 (28%), Gaps = 24/207 (11%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
             + +   G + ++  P       T   P ++ ++G++ A +G  RDD   +++L ++  
Sbjct: 5   KLIRINAYGIINSFRIPLHMTIHDTLDLPVKTHIIGMIAAAMGYLRDDKEKIESLYKNTS 64

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWL 122
             +           + +   +               K  E     R+     ++T+ +  
Sbjct: 65  IGIYGTSYSKFYDLIRIYKYK--------------GKEVEVSLVNRQINYKNNYTIYI-- 108

Query: 123 TPHATMVISELEKAVLKPRYTPYLGRRSCPLTHP----LFLGTCQASDPQKALLNYEPVG 178
                  + E+   +  P +   LG+    +       +     +      +        
Sbjct: 109 ---ENNNLEEIYNFLKNPVFALSLGKAHDLINIKDISIINATIVEDDYIDLSNTVLPFNL 165

Query: 179 GDIYSEESVTGHHLKFT-ARDEPMITL 204
            D    +     ++        P+   
Sbjct: 166 YDFEIIDLKDNTNITPFQTYKLPLSFN 192


>UniRef50_B8DAB1 Crispr-associated protein Cas5, tneap subtype n=3 Tax=Firmicutes
           RepID=B8DAB1_LISMH
          Length = 207

 Score = 99.7 bits (247), Expect = 7e-20,   Method: Composition-based stats.
 Identities = 25/155 (16%), Positives = 52/155 (33%), Gaps = 12/155 (7%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              + ++L   +  + +PT    + T   P  S ++G++    G        ++   +  
Sbjct: 1   MKAIRVKLWQDLVNFKKPTSFQLKETYPLPPYSTVIGMVHTLCGF--TSYHEMKISIQGK 58

Query: 62  QFAVRCDELILD-DRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
            F+   D       +         +   +      RG        +  E + D    + +
Sbjct: 59  YFSKVNDLATRYEFKNGMTYDASRHQIKVDKYGVSRG-------VSTVELIVDLELLLHI 111

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTH 155
              P  + ++  +EKA  +P   P LGRR    T 
Sbjct: 112 --IPEDSSLVPIIEKAFSEPIEFPSLGRREDIATI 144


>UniRef50_C1TQC8 CRISPR-associated protein Cas5, Hmari subtype n=1
           Tax=Dethiosulfovibrio peptidovorans DSM 11002
           RepID=C1TQC8_9BACT
          Length = 236

 Score = 99.3 bits (246), Expect = 8e-20,   Method: Composition-based stats.
 Identities = 34/224 (15%), Positives = 67/224 (29%), Gaps = 35/224 (15%)

Query: 6   ILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDT------SSLQALSE 59
           +  +  PM  + +P    +  +  FP  + + GL+ A  GI              + LS 
Sbjct: 4   VFDVTSPMAMFRKPYTTTSSVSYAFPPPTAVAGLISAISGISNGSDKSGCGAQYWKDLSG 63

Query: 60  -SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV 118
            S+   +R     +               V            +  IQ   +++    + +
Sbjct: 64  TSIAVGIRGKVSWMSQALN-------MWNVKNP-------GKNAHIQVKHQFVARPRYRI 109

Query: 119 ALWLTPHATMVISELEKAVLK--PRYTPYLGRRSCPLTHPLFLGTCQASDPQK---ALLN 173
            +            L+  + +    YTP LG  +  L    ++G   ++ P     AL  
Sbjct: 110 YVSGGIED-----RLDGYLKRGAFVYTPCLG-TAYALADLEYVGRFGSASPDGGPLALDT 163

Query: 174 YEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIK 217
             P    +  +   +G          P+     +   R   VI 
Sbjct: 164 IVPWTDGMTVDVLSSG---GAFKERVPLQFDVGRGLVRACSVIY 204


>UniRef50_B1LAM2 CRISPR-associated protein Cas5, Hmari subtype n=2 Tax=Thermotoga
           RepID=B1LAM2_THESQ
          Length = 220

 Score = 99.0 bits (245), Expect = 1e-19,   Method: Composition-based stats.
 Identities = 34/208 (16%), Positives = 64/208 (30%), Gaps = 25/208 (12%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L+  ++     + +P    +  T  FP R+ LLGL+G  LG       S     +S 
Sbjct: 1   MKVLVFDVSTSYALFRRPYTTTSSYTLPFPPRTALLGLVGCVLG------YSTPEKLDSA 54

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           + AV+    +   R           T     E  +  K+ +  +   + L + ++ V   
Sbjct: 55  KVAVQIKNPLKFLR-----------TGTNFVETKKDKKASKRTRISLQLLKNPAYRVFFS 103

Query: 122 LTPHATMVISELEKAVLK--PRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGG 179
                      L+  +      +TPYLG  S       ++G  +A+  +        V  
Sbjct: 104 WEDKD---FERLKNLLEHNETIFTPYLGVASFIAKLD-YVGEYEATRVEDFPCEVHTVVP 159

Query: 180 DIYSEESVTGHHLKFTARDEPMITLPRQ 207
           +      V                   +
Sbjct: 160 NTIK--IVPEPSHYLVFERVTRRMDKER 185


>UniRef50_UPI0000F51712 CRISPR-associated Cas5 family Hmari subtype protein n=1
           Tax=Ferroplasma acidarmanus fer1 RepID=UPI0000F51712
          Length = 256

 Score = 99.0 bits (245), Expect = 1e-19,   Method: Composition-based stats.
 Identities = 25/213 (11%), Positives = 61/213 (28%), Gaps = 13/213 (6%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
            LI  +     ++ +     +  T  FP R+ L G++GA +G   D          ++  
Sbjct: 1   MLIFDIKAKFASFKKLYTNSSSMTYMFPPRTTLEGIIGAIMGYDFDSYYEKFNFKYTL-I 59

Query: 64  AVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYL-----CDASFTV 118
           A     +I          ++        +        + T   +   L      +  + +
Sbjct: 60  ATSLKSIIRTYMTNLNY-IKIVDNNYFIKNIINNNGYNYTQIPFEFLLPENFSKNIIYRI 118

Query: 119 ALWLTPHATMVISELEKAV--LKPRYTPYLGRRSCPLTHP-LFLGTCQASDPQKALLNYE 175
                     ++++LE+ +    P Y   LG  +   +   +  G          +    
Sbjct: 119 Y--FFSKDDDLMAKLEEKIIKNNPVYPVSLGNANMLASINYIAKGKISKIKTGDPIKINS 176

Query: 176 PVGGDIYSEESVTGHHLKFTARDEPMITLPRQF 208
           P       +     + +       P+     ++
Sbjct: 177 PAPMKYI-KGIPANNDIYLQKDVFPVSFDLNRY 208


>UniRef50_D2QT47 CRISPR-associated protein Cas5 n=1 Tax=Spirosoma linguale DSM 74
           RepID=D2QT47_9SPHI
          Length = 237

 Score = 98.6 bits (244), Expect = 1e-19,   Method: Composition-based stats.
 Identities = 32/225 (14%), Positives = 58/225 (25%), Gaps = 28/225 (12%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
                + L     ++  P F+    +   P  + L+GL GA LG+               
Sbjct: 1   MLCCTIELKSVTASFRNPEFQNFHKSFPLPPPTALIGLAGAALGLSPRMAQDFLD----- 55

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
                 ++             RD          Y  L    +    RE   +  +   L 
Sbjct: 56  -----TNQFQAGVSGKGEGMTRDLW-------KYDRLTGTGSSIILREIYVNPHYR--LV 101

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTH---PLFLGTCQASDPQKALLNYEPVG 178
                   + +L+ A   P Y   LG+           L     +    +  L+  + V 
Sbjct: 102 FGSDNHEAVEQLKAAFDSPVYALTLGQSDSLAKIVRTTLTDAVVEGQTLENTLVEGDIVP 161

Query: 179 GDIYSEE-----SVTGHHLKFTARDEPMITLPR-QFASREWYVIK 217
             +         S++       A   P     +  +  R     K
Sbjct: 162 AILEQVLYGGTFSLSLSTSDPIAYQLPTRFNYKADYGMRTVSERK 206


>UniRef50_A3DHS3 CRISPR-associated protein Cas5 n=3 Tax=Clostridium thermocellum
           RepID=A3DHS3_CLOTH
          Length = 241

 Score = 98.6 bits (244), Expect = 2e-19,   Method: Composition-based stats.
 Identities = 35/188 (18%), Positives = 56/188 (29%), Gaps = 19/188 (10%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              LI+ L     ++  P  +    T   P  S + G+ GA LG+  +D     AL+   
Sbjct: 1   MYGLIVTLYAKTASFRDPGAQLYHETMSLPPPSTITGIAGAALGLSFED-----ALAFMK 55

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           + AV            S    +D       +               R +L D    +   
Sbjct: 56  ENAVMVGC-----NGSSEGRGKDLWNYTKIKSGEIT-----NAIIIRNFLADLKVEIFFA 105

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASD-PQKALLNYEPVGGD 180
                  VI+ L  A   P Y   LG           +   +     +K +L    + GD
Sbjct: 106 C--EKREVITRLADAFENPVYAITLGNSDEIAKI-CSIEIFEEISCEKKKILTNTWLPGD 162

Query: 181 IYSEESVT 188
              +  V 
Sbjct: 163 YSRKLKVD 170


>UniRef50_C3HBA5 Putative uncharacterized protein n=2 Tax=Bacillus thuringiensis
           RepID=C3HBA5_BACTU
          Length = 255

 Score = 98.2 bits (243), Expect = 2e-19,   Method: Composition-based stats.
 Identities = 30/227 (13%), Positives = 62/227 (27%), Gaps = 30/227 (13%)

Query: 2   RSYLILRLAGPMQAWGQPTFE-GTRPTGRFPTRSGLLGLLGACLGIQRD----------- 49
              +   L G    + +P        T     +  L GLLGA +G               
Sbjct: 1   MKAIAFELKGRTAFFKKPDVNANIYFTYSHIHKIALYGLLGAIIGAGGYTQQQKSIIDEG 60

Query: 50  -----DTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETI 104
                       L   ++ ++                 +           Y   ++   +
Sbjct: 61  NSTSNQYPEFYQLLNKLKVSI-------VPHGDRGYFSKKSQVFNNTV-GYASREAGGNL 112

Query: 105 QTWREYLCDASFTVALWLTPH-ATMVISELEKAVLKP--RYTPYLGRRSCPLTHP-LFLG 160
               ++L +  +T+ LW        + + L+  ++    +Y PYLG+   P     + L 
Sbjct: 113 IVQEQWLENPHWTIYLWNDGSLEEEIFNNLKNHLISSAYKYLPYLGKNDHPANIEHVRLV 172

Query: 161 TCQASDPQKALLNYEPVGGDIYSEES-VTGHHLKFTARDEPMITLPR 206
             +  D    + +        +S         + F     P+   P 
Sbjct: 173 ELEEVDELCGIESLVYSKDVYFSTNGTYDNTPIFFFEEHIPIQLNPD 219


>UniRef50_A4FXZ5 CRISPR-associated protein Cas5 n=1 Tax=Methanococcus maripaludis C5
           RepID=A4FXZ5_METM5
          Length = 233

 Score = 97.8 bits (242), Expect = 3e-19,   Method: Composition-based stats.
 Identities = 24/211 (11%), Positives = 55/211 (26%), Gaps = 24/211 (11%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
             L   L G    + +     +  T   P R+ L+G++ + L  +RD   +  +  ++  
Sbjct: 5   KILEFELYGKFAHFKKFYSNASSLTYSVPPRTVLMGIVASVLEEKRDSYYNWLS-KDNAG 63

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWL 122
           F ++                  Y+T    +           +        +  + V    
Sbjct: 64  FGIQILSESRKGM---------YNTNYIGKNGTSPTSVEIVMPVN----HNVRYMVY--F 108

Query: 123 TPHATMVISELEKAV--LKPRYTPYLGRRSCPLTHPLFLGTCQASDPQ----KALLNYEP 176
                      +K +      Y  Y G+R              A   +      L++   
Sbjct: 109 YSTDQEKYELFKKRLIDENWGYGLYFGQRQFRAFAKFHKEYVGAEIVRKNDFDGLVSTCI 168

Query: 177 VGGDIYSEESVTGHHLKFTARDEPMITLPRQ 207
              +I   +       +      P+     +
Sbjct: 169 SENNII--DINFEKEKQLLRERMPIDFNGSR 197


>UniRef50_B8DZH7 CRISPR-associated protein Cas5, Hmari subtype n=6 Tax=Bacteria
           RepID=B8DZH7_DICTD
          Length = 238

 Score = 97.4 bits (241), Expect = 3e-19,   Method: Composition-based stats.
 Identities = 27/226 (11%), Positives = 67/226 (29%), Gaps = 11/226 (4%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L+  + G +  + +     +  +  FP    +LG++GA  GI R     +    E+ 
Sbjct: 1   MKVLVFDIFGDLAHFRRFYTTSSPLSFSFPPPPTILGMIGAIAGIDRKKYLEVL-CPENC 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           + +++    I   R          +T     +  +    +   Q   E++ D  + V   
Sbjct: 60  KISLQIMNPIKKIRLGLNLI----NTKDNFWQPVKTKNHNARTQVKTEFIKDPRYRVY-- 113

Query: 122 LTPHATMVISELEKAVLK--PRYTPYLGRRSCPLTHPLF--LGTCQASDPQKALLNYEPV 177
                  +  ++   +      +T  LG                 +  + ++  ++    
Sbjct: 114 FYHKDENIFEDVINKIKNHETFFTFSLGLSELIGDFQFIKVAEFIEIKEKEEVYIHSLLP 173

Query: 178 GGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVS 223
              I   + +      +     P+I    +   +   VI       
Sbjct: 174 MSYISESKIIFEEGKSYFRERIPVIMNKERVVEKYEDVIYESNGKP 219


>UniRef50_B5IGN1 CRISPR-associated protein Cas5 n=1 Tax=Aciduliprofundum boonei T469
           RepID=B5IGN1_9EURY
          Length = 236

 Score = 97.0 bits (240), Expect = 4e-19,   Method: Composition-based stats.
 Identities = 31/216 (14%), Positives = 67/216 (31%), Gaps = 24/216 (11%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGI-QRDDTSSLQALSES 60
              L  +L     ++ +        T   P  + ++GLLG+ LG+  R+  +    L++ 
Sbjct: 1   MEVLTAKLRAISVSFRRILDFNYHRTYPLPPPTTIVGLLGSALGLSDRELWNEYNGLND- 59

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           + FAV                 +D  ++   +         E    +RE L    +   +
Sbjct: 60  ISFAVLSLR--------KPGFAKDMWSIQKIKNGRI----SERSPYFRELLFYPEY---V 104

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180
            +    +  +  +  A+  P Y   LGR    L   + +   +  +  + + +   +  D
Sbjct: 105 LIFNGDSKSLECVRDALNNPEYALSLGR-EDELVRVIDVQW-ERVEKGEPVFSGTVLPFD 162

Query: 181 IYSEESVTGHHLKFTARD-----EPMITLPRQFASR 211
           I   +                   P      +   R
Sbjct: 163 IREYKFSPIMEEGIFIEPPVIDKLPTSFSVDRKGIR 198


>UniRef50_C1QDM0 CRISPR-associated protein Cas5 n=1 Tax=Brachyspira murdochii DSM
           12563 RepID=C1QDM0_9SPIR
          Length = 246

 Score = 97.0 bits (240), Expect = 4e-19,   Method: Composition-based stats.
 Identities = 26/190 (13%), Positives = 60/190 (31%), Gaps = 10/190 (5%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
             + +     M  + +P+    + + + P  S ++G++      +  +   ++   +   
Sbjct: 7   KAIKIECYQNMPNYKRPSSIQFQESFKLPPYSTVIGMIHKVCSCKSGEYMPMKVSIQGET 66

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWL 122
            +   D        +     R    V      + G+        + E + D +  + +  
Sbjct: 67  KSSLTDLYTRYFFGIKYDPSRHQLKVKNPDGSFDGITKG---LGYAEVIVDVNLIIHIV- 122

Query: 123 TPHATMVISELEKAVLKPRYTPYLGRRSCPL-----THPLFLGTCQASDPQKALLNYEPV 177
            P    +   + K + KP   P LGR    L     +      T +      A + Y  +
Sbjct: 123 -PEDESLFDFILKGLKKPCVYPALGRHEDILRIDNVSIVETEKTDEIEMFYDAYIPYSMI 181

Query: 178 GGDIYSEESV 187
              I  EE +
Sbjct: 182 DNIINKEELI 191


>UniRef50_B9D004 Crispr-associated protein Cas5 n=1 Tax=Campylobacter rectus RM3267
           RepID=B9D004_WOLRE
          Length = 246

 Score = 96.6 bits (239), Expect = 5e-19,   Method: Composition-based stats.
 Identities = 27/213 (12%), Positives = 56/213 (26%), Gaps = 25/213 (11%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRD-DTSSLQALSESVQ 62
               ++ G    +  P       T   P ++ + G+L A LGI    +         SV 
Sbjct: 1   MFAFKIWGKFACFRDPLGISQNITLPIPPKTTICGMLAALLGIDNYLNDDRFDDFKYSVI 60

Query: 63  FAVRCDELILDDRRVS----------VTGLR-DYHTVLGAREDYRGLKSHETIQTWREYL 111
                 +       ++           + L+ D   +     D             RE L
Sbjct: 61  LDAPILKKSFSQNYINDYTKFTKSHLNSLLKFDMQKISLGLRD----NKAPQKPINRELL 116

Query: 112 CDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPL-FLGTCQASDPQKA 170
               + + +         I  L+K +   +++ YLG            +   +     + 
Sbjct: 117 IYPKYIIFIDKFKLEEEAIYNLKKRI--CKFSFYLGNSEFAGNFEFMEITNYEEKKFDEI 174

Query: 171 LLNYEPVGGDIYSEESVTGHHLKFTARDEPMIT 203
            ++   +  D           L       P+  
Sbjct: 175 NIDSFVLQDD-VKNIDFEESVLYS-----PISF 201


>UniRef50_B7AS04 Putative uncharacterized protein n=1 Tax=Bacteroides pectinophilus
           ATCC 43243 RepID=B7AS04_9BACE
          Length = 241

 Score = 96.6 bits (239), Expect = 5e-19,   Method: Composition-based stats.
 Identities = 21/157 (13%), Positives = 49/157 (31%), Gaps = 11/157 (7%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M   + L+    +  + +P+    + T   P  S + G++ A  G +      L  +  S
Sbjct: 1   MVKAIRLQCYQNLANYRKPSSFIIKETYPLPPYSTVSGMIHAACGFK-----ELHRMKLS 55

Query: 61  VQFAVR--CDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV 118
           +Q   R    E+       +     +    +  ++               E +C+ +  +
Sbjct: 56  IQGTNRGTISEVYTRYSFSAGAKYEEGRHQICLKDGENYGIYKG--VANAELVCENNMII 113

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTH 155
            +   P     +  +   +  P     LGR    +  
Sbjct: 114 HI--LPEREEDMDVIYNGLSNPLMYLSLGRYEDIIDI 148


>UniRef50_O66696 Putative uncharacterized protein n=2 Tax=Aquificaceae
           RepID=O66696_AQUAE
          Length = 219

 Score = 96.6 bits (239), Expect = 6e-19,   Method: Composition-based stats.
 Identities = 40/228 (17%), Positives = 71/228 (31%), Gaps = 28/228 (12%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L      P+  +  P       T   P  S ++GLL    G +              
Sbjct: 1   MECLKAEFFSPIALFKTPFSIKGIETYPLPPYSTVIGLLYTASGKKW------------- 47

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
               + +   +  +       RDY   +  R+  +  K  ET+        +   TV + 
Sbjct: 48  ----KGERFNISVQGDYEAIFRDY---VRFRKYNKKDKKLETLPLEVPLFYNFRLTVHIL 100

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTH-PLFLGTCQASDPQKA-LLNYEPVGG 179
                  ++ E EKA+  P   PYL     P+    + +  C+        +     +  
Sbjct: 101 ---GDENLLKEFEKALKFPYVFPYLSGGEYPVKITKVKMVACRKEYFDTFNIPKNAYIPE 157

Query: 180 DIYSEESVTGHHLKFTARDEP---MITLPRQFASREWYVIKGGMDVSQ 224
           +I++EE              P   +   PRQ      Y ++ G  VS+
Sbjct: 158 NIFTEEFRVSLEGHGVYYRVPSFLISQKPRQHEWVGVYYVQKGTKVSE 205


>UniRef50_D1N0K0 Putative uncharacterized protein n=1 Tax=Victivallis vadensis ATCC
           BAA-548 RepID=D1N0K0_9BACT
          Length = 239

 Score = 96.3 bits (238), Expect = 7e-19,   Method: Composition-based stats.
 Identities = 37/226 (16%), Positives = 66/226 (29%), Gaps = 31/226 (13%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGI--QRDDTSSLQALSE 59
            S LI  LAG M  W          +   P    L G++GA LG    R   +      +
Sbjct: 1   MSILIFELAGEMAMWRNVYESMGSYSCLGPAPGNLAGVIGAALGFASPRSQAAEKPDAKQ 60

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHT---VLGAREDYRGLKSHETIQTWR-------- 108
              +        +    ++     D+H     +G          +   +  R        
Sbjct: 61  LKNWDKAGLPWPVSPELLAWEETNDFHVACRWIGKFPKRVPWNINGCKEINRSDNLRLQQ 120

Query: 109 EYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSC------------PLTHP 156
           + + D ++ VA+ L  +       +  A+ KP +   LG   C                P
Sbjct: 121 QVILDPAYEVAVALPAYEA---ERVAAALRKPAFPLCLGASFCRAIVRNVRIEDAVPESP 177

Query: 157 LFLGTCQASDPQKALLNYEPV--GGDIYSEESVTGHHLKFTARDEP 200
            +          +A      +   G  +      G+ +  T  D+P
Sbjct: 178 FWAFRTDGGALGEATPFSRHIVNPGSCFERIRSDGYWIYPTP-DQP 222


>UniRef50_D0MJ68 CRISPR-associated protein Cas5 n=1 Tax=Rhodothermus marinus DSM
           4252 RepID=D0MJ68_RHOM4
          Length = 236

 Score = 95.9 bits (237), Expect = 8e-19,   Method: Composition-based stats.
 Identities = 37/149 (24%), Positives = 57/149 (38%), Gaps = 15/149 (10%)

Query: 3   SYLILRLAGPMQAWGQPTF-EGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             + + LAGP+ ++  P F  G +PT   P  S + GL+ A LG   D         E++
Sbjct: 7   EAVKVELAGPVASFRYPHFLIGRQPTYPMPPPSTIYGLISAALGRFPD--------PEAL 58

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           QFA R +        V        +T        + L++   I   RE+L     T+ + 
Sbjct: 59  QFAYRFECARHRVDDVETIWFVQPNTATRGEAARKNLEATSNILP-REWLVHPRLTLYVT 117

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRS 150
                   +  L +A   P Y   LGR  
Sbjct: 118 GDE-----LEALYRAFRSPCYILTLGRSQ 141


>UniRef50_A9BGY6 CRISPR-associated protein Cas5, Hmari subtype n=1 Tax=Petrotoga
           mobilis SJ95 RepID=A9BGY6_PETMO
          Length = 242

 Score = 95.1 bits (235), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 25/235 (10%), Positives = 69/235 (29%), Gaps = 32/235 (13%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQR--DDTSSLQALSESV 61
            L+  + G    + +     +  +  FP  + + GL+ A +G++   ++ + L +  E++
Sbjct: 2   ALVFDITGEYAMFRKFYTTTSSASYPFPPPTAVGGLIAAIIGVENKSENKAHLASYWEAL 61

Query: 62  ---QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV 118
              + ++     I             + T +         K    I    +++    + +
Sbjct: 62  YGNRISISIRSPIKW-----------FTTSINLWNYKDPKKGIHNIIKH-QFVKRPKYRI 109

Query: 119 ALWLTPHATMVISELEKAVL--KPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEP 176
            +           +L+  +      +TPYLG                       +     
Sbjct: 110 YVEGPIE-----EKLKPFLEQGNFVFTPYLGTAYSFANIDYIGSFNPVKINDGEVNIKSI 164

Query: 177 VGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIK-------GGMDVSQ 224
           +  DI  + ++            P+     +  ++   V           +D  +
Sbjct: 165 IPADIKPKINLKKTKG-IFKDIVPLQMDEERGLTKSLSVFYPVNSDTGIIVDNPE 218


>UniRef50_UPI0001B51C2B CRISPR-associated Cas5 family protein n=1 Tax=Streptomyces
           viridochromogenes DSM 40736 RepID=UPI0001B51C2B
          Length = 278

 Score = 94.7 bits (234), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 61/280 (21%), Positives = 86/280 (30%), Gaps = 70/280 (25%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M S L+LRLAGP+Q+WG       R T   PT+SG+ GL+ A LG+ R D          
Sbjct: 1   MTSVLLLRLAGPLQSWGALARFDRRDTLNRPTKSGVTGLVAAALGLDRADD---LGALTD 57

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLK--------------------S 100
           ++FAVR D           T +RD+H V       R                        
Sbjct: 58  LRFAVRADR--------PGTAVRDFHIVGSGTYPLRPRDLITDHRRAEKAAAALETSTGP 109

Query: 101 HETIQTWR----------EYLCDASFTVALWLTPHATMVI-------------------S 131
                  R          E   D    V L        ++                    
Sbjct: 110 VFGHLAARSVTKWYGAPKEIAPDPKTGVLLAGNTTRDAMMTTRWYLADAAFVAAVEHPDQ 169

Query: 132 ELEKAVLKPRYTP----YLGRRSCPLTHPL----FLGTCQASDPQKALLNYEPVGGDIYS 183
            L   +      P    +LGR+SCP +  +      GT +      ALL           
Sbjct: 170 NLLHRISHAVEHPKRLLWLGRKSCPPSGTISGGVHPGTAETILTTTALLPNATSPQPWAW 229

Query: 184 EESVTGHHLKFTARDEPMITLP--RQFASREWYVIKGGMD 221
            E+  G        D+P+   P  R   +R     +   +
Sbjct: 230 IEAAPGTPGAAQRTDQPVTYHPEHRTHTARWETRTRISPE 269


>UniRef50_B7GIV5 CRISPR system related protein, RAMP superfamily n=3 Tax=Bacillaceae
           RepID=B7GIV5_ANOFW
          Length = 233

 Score = 94.7 bits (234), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 28/226 (12%), Positives = 67/226 (29%), Gaps = 11/226 (4%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L L+L      + +P       T   P  S + G++ A L     D      LS   
Sbjct: 1   MKALRLKLFQETACYKKPFASKVAETYPLPPYSTVKGMIHALL---NADQFIPMRLSVQG 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHE--TIQTWREYLCDASFTVA 119
            +  +  +                  + G          +E  T+  +   L +    + 
Sbjct: 58  TYEEKLLDYQRYYFFKKKELSSFPLVLDGLARMEFSYDKNEITTMPMYTHLLHNVHLLIH 117

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLF-LGTCQASDPQKALLNYEPVG 178
           +        ++ ++  A+        LGR    +    + L   Q  + +K L     + 
Sbjct: 118 IEA---EQHILKQIIHAIEYSMTHYSLGRWEDLVRIDEYKLVDVQELEEEKTLQWNAYIP 174

Query: 179 GDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVSQ 224
            +    E+ +  +      +  ++   RQ+       ++  ++  +
Sbjct: 175 SNFLDRETKSIPYQLNWKYE--IVNGIRQWEKINVGYVQKEIEAPE 218


>UniRef50_A1ZHZ1 Crispr-associated protein Cas5, hmari subtype n=1 Tax=Microscilla
           marina ATCC 23134 RepID=A1ZHZ1_9SPHI
          Length = 250

 Score = 94.3 bits (233), Expect = 3e-18,   Method: Composition-based stats.
 Identities = 29/167 (17%), Positives = 53/167 (31%), Gaps = 21/167 (12%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQA------ 56
           + LI  +      + +     +  T   P R  L+GLLGA +GI+R+ ++          
Sbjct: 5   TILIFDIESEYGHFRKFNTTTSPLTYPIPPRPALVGLLGAIVGIEREASAGKFNEGVTPV 64

Query: 57  ----LSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLC 112
                    + AV+    +             ++ +   +         +  Q   E L 
Sbjct: 65  AELFAKPDTELAVQLINPVKKVPMA-------FNLLDTEKSGASFFNIKQRTQIEFELLK 117

Query: 113 DASFTVALWLTPHATMVISELEKAVLK--PRYTPYLGRRSCPLTHPL 157
              F V +     A  ++  L   +      +TPYLG      T   
Sbjct: 118 HPCFRVFVACANDA--LMQPLVDNIQHNQAHFTPYLGLSQFTATFNF 162


>UniRef50_A6DAF2 Putative uncharacterized protein n=1 Tax=Caminibacter
           mediatlanticus TB-2 RepID=A6DAF2_9PROT
          Length = 233

 Score = 93.6 bits (231), Expect = 4e-18,   Method: Composition-based stats.
 Identities = 19/158 (12%), Positives = 45/158 (28%), Gaps = 10/158 (6%)

Query: 2   RSYLILRLAGPMQAWGQPTFE-GTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
              +   L+G    + +P        T     +  LLG+ GA LG+   +          
Sbjct: 1   MKAISFNLSGKFAHFKKPDVNSNVYFTYSHIHKIALLGIFGAILGLDGYNKDIKDYPEFY 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
            +      + +                       Y   +    +    ++L + ++ + +
Sbjct: 61  KR-----LKHLKVSIIPKEVMFSKKIITFNNSVGYASKEQGGNLVVKEQWLENPAWEILV 115

Query: 121 WLTPHATMVISELEKAV--LKPRYTPYLGRRSCPLTHP 156
                     ++L + +   +  Y PYLG+        
Sbjct: 116 KDDGSDK--FNKLREKLFNKECVYIPYLGKNDHFANIS 151


>UniRef50_A5ILM6 CRISPR-associated protein Cas5 family n=3 Tax=Thermotogaceae
           RepID=A5ILM6_THEP1
          Length = 260

 Score = 93.6 bits (231), Expect = 5e-18,   Method: Composition-based stats.
 Identities = 24/201 (11%), Positives = 64/201 (31%), Gaps = 14/201 (6%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L + +      +  P F   R T   P  S  +GL+   L    D++     L+   
Sbjct: 1   MKLLRIEVKASTAHFAIPFFIFERKTFPIPMYSTAIGLICNILS---DESKIESFLNSEF 57

Query: 62  QFAV------RCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDAS 115
             A+        +E          + ++ + ++     ++        + T  + L +  
Sbjct: 58  SMAIVGNHEGVVEEYTWLRNLEKGSHVKKFKSLRNREINHEIEHPGGQMPTRIQTLVNPR 117

Query: 116 FTVALWLTPHATMVISELEKAVLKPRYT--PYLGRRSCPLTHPLFLGTCQASDPQKALLN 173
             + +        V+  +++++  P Y    +LGR    +    +           +   
Sbjct: 118 VDLFVKA---KEDVLEMIKQSLENPGYISRIHLGRSEDTVDEINYELVNCEKKKVFSTGG 174

Query: 174 YEPVGGDIYSEESVTGHHLKF 194
           Y  +    +++E    ++  +
Sbjct: 175 YTWIPSPEFADEVCDNYNELY 195


>UniRef50_Q12WX6 CRISPR-associated protein Cas5, Hmari subtype n=1
           Tax=Methanococcoides burtonii DSM 6242
           RepID=Q12WX6_METBU
          Length = 264

 Score = 93.6 bits (231), Expect = 5e-18,   Method: Composition-based stats.
 Identities = 28/205 (13%), Positives = 64/205 (31%), Gaps = 12/205 (5%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
             L  RL G    + QP     R T     +  LLGL+G+ +G+     +++     S  
Sbjct: 31  KLLTFRLYGSFAHFNQPISNRFRNTYSIIPKPQLLGLIGSIVGLSGYKNAAVSPEFYSKL 90

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWL 122
             ++             T    Y+++     +         +    + L D  + V + +
Sbjct: 91  SDLKVFIKCNSLSEKKFTLS--YNSLNSFLNNRIDS-GSPNVIIKEQVLLDPDYEVGIVV 147

Query: 123 TPHATMVISELEK-AVLKPRYTPYLGRRSCPLTHPL-FLGTCQASDPQKALLNYEPVGGD 180
             +  + +  ++K  +    +  Y G+           L   +  +      +       
Sbjct: 148 NENNPLHLEIIDKIRMNCGVFPIYFGKNEFFANVQFGHLKDFEYDN------SESNKCCS 201

Query: 181 IYSEESVTGHHLKFTARD-EPMITL 204
           I+  E V   + +    +  P+   
Sbjct: 202 IFPFEEVESVNTRNMKLELLPVDFD 226


>UniRef50_B1BR50 Crispr-associated protein Cas5 n=1 Tax=Clostridium perfringens E
           str. JGS1987 RepID=B1BR50_CLOPE
          Length = 233

 Score = 92.8 bits (229), Expect = 7e-18,   Method: Composition-based stats.
 Identities = 25/208 (12%), Positives = 49/208 (23%), Gaps = 10/208 (4%)

Query: 2   RSYLILRLAGPMQAWGQPTFE--GTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE 59
              +   ++G    +  P +       +     +  LLG+LGA LG             E
Sbjct: 1   MKCIKFNISGKYAFFKNPEYNLNSYEYSFEHIHKPALLGILGAILGFDGKLQFKKNNKLE 60

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
                    + I        +     H                +    R  L +  +T+ 
Sbjct: 61  YY----EELKNIKVAIEPYSSIFE--HFEYDFVNGTGYANKGNSQMIKRMCLYNPLWTIY 114

Query: 120 LWLTPHATMVISELEKAV--LKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPV 177
           +        +   L K +   K +Y  YLG  S                     +    +
Sbjct: 115 ILGESIDEKMYINLNKHLSSHKSKYPIYLGDNSFKAKISNVEEIEVEPIQTNKNIIISSI 174

Query: 178 GGDIYSEESVTGHHLKFTARDEPMITLP 205
                 +       L    + + +    
Sbjct: 175 FKRKILKCEYDEIKLYLPIKLQEVSLNY 202


>UniRef50_A4XM40 CRISPR-associated protein Cas5 family n=3 Tax=Clostridia
           RepID=A4XM40_CALS8
          Length = 249

 Score = 92.4 bits (228), Expect = 1e-17,   Method: Composition-based stats.
 Identities = 22/151 (14%), Positives = 43/151 (28%), Gaps = 11/151 (7%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
             L ++L  P   + +P   G   +   P  S + G L   LG +  +   +        
Sbjct: 4   KLLKIKLYQPFANFRKPFSYGIVDSYPLPPPSTVKGWLHNILGAKNGEYYKMAVSICGKF 63

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWL 122
            ++  D      R +    LR       A               +   L D    + +  
Sbjct: 64  NSIVYD----IQRIIKFDRLRK--EDSSAPILKDVSARVINDVIYVTNLVDVELCIHVNA 117

Query: 123 TPHATMVISELEKAVLKPRYTPYLGRRSCPL 153
                 ++  +   +    +   LGR+   L
Sbjct: 118 ---EQEILERISHNIFNSYWG--LGRKEDLL 143


>UniRef50_Q1Q0Z9 Putative uncharacterized protein n=1 Tax=Candidatus Kuenenia
           stuttgartiensis RepID=Q1Q0Z9_9BACT
          Length = 265

 Score = 92.0 bits (227), Expect = 1e-17,   Method: Composition-based stats.
 Identities = 34/240 (14%), Positives = 72/240 (30%), Gaps = 28/240 (11%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRP-TGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
            +     LAG M  + +         +  F  +  +LG++GA LGI      S       
Sbjct: 1   MNVFSFELAGDMAFFKKNDANDMVYISYNFLHKPAVLGIIGAILGIPGYS-ESKAKQHPD 59

Query: 61  VQFAVRCDELILDDRRVSV--TGLRDYHTVLGAREDYRGLKSHETIQTWREYL--CDASF 116
               ++  ++ +           +  ++          G +        +  +   +  +
Sbjct: 60  FYTNLKDMKIAILPHYEKPLKKVITGFNNASCLASKSSGGQGQTWQIREQILIGEQEIRY 119

Query: 117 TVALWLTPHATM-VISELEKAV--LKPRYTPYLGRRSCPL---------THPLFLGTCQA 164
           TV +         +IS+L+K +   +  Y  Y G+                PL       
Sbjct: 120 TVFVLDNNAIQDGLISKLKKLLINRESEYPLYFGKNEFFAYHENYQEYEAAPLSASEASV 179

Query: 165 SDPQKA-------LLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIK 217
               KA       L  +     D + ++   G+ +       P     R F  ++ +V+ 
Sbjct: 180 CGLVKAGDKNTNILREFSFEDFDPFEKKLNEGYTIYEH---LPYDFDARGFYKKDVFVLT 236


>UniRef50_C4IBN8 CRISPR-associated protein Cas5 n=5 Tax=Bacteria RepID=C4IBN8_CLOBU
          Length = 262

 Score = 92.0 bits (227), Expect = 1e-17,   Method: Composition-based stats.
 Identities = 27/169 (15%), Positives = 56/169 (33%), Gaps = 20/169 (11%)

Query: 2   RSYLILRLAGPMQAWGQPTFE-GTRPTGRFPTRSGLLGLLGACLGIQRDD---------- 50
              L   L G    + +P        T     +  L GLLGA LG    +          
Sbjct: 1   MRILKFTLRGKSGFFKKPDVNSNLYFTYGNIHKVALTGLLGAVLGYGGYNSMNIKNIFNK 60

Query: 51  --TSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWR 108
               ++Q   E  +  ++  ++ +          +       +   Y   +    +    
Sbjct: 61  KKKEAVQDFPEFYE-RLKDLKISIVPNGEKGFISKKVQIFNNSV-GYASKEQGGNLIVKE 118

Query: 109 EYLCDASFTVALWLTPHATMVISELEKAV--LKPRYTPYLGRRSCPLTH 155
           ++L + S+ + + +    +    ++E+A+   K  YTPYLG+       
Sbjct: 119 QWLENPSWDIYIIIDDEES---EKIEEAITKHKTVYTPYLGKNDHIADI 164


>UniRef50_O57910 Putative uncharacterized protein PH0171 n=1 Tax=Pyrococcus
           horikoshii RepID=O57910_PYRHO
          Length = 227

 Score = 92.0 bits (227), Expect = 1e-17,   Method: Composition-based stats.
 Identities = 29/212 (13%), Positives = 63/212 (29%), Gaps = 23/212 (10%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           LI+        +  P       T  FP ++  +G+L  C+G+        + L E +++ 
Sbjct: 7   LIVDARPLQAHFRIPHTSLLLDTYPFPPKTTAVGMLAGCMGLG---EEGFKKLLEKIKYG 63

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTP 124
           V  +             + +   +              +    R  L    F +      
Sbjct: 64  VIIE--------DPGEKIEEVSVIYK-------NPYSPSYPITRVSLYKPRFRMFFA--- 105

Query: 125 HATMVISELEKAVLKPRYTPYLGRRS--CPLTHPLFLGTCQASDPQKALLNYEPVGGDIY 182
               VI E  + +L P++ PY+G            ++      + ++ +L          
Sbjct: 106 GEERVIEEAYEGLLDPKFVPYMGDSESLFYPGKKRYVEVVDVQEGKEDILRSVIPEVKFK 165

Query: 183 SEESVTGHHLKFTARDEPMITLPRQFASREWY 214
               +    L     + P+    +  + R  Y
Sbjct: 166 EFVPLRRKVLVPKVYEAPVKFTYKGKSRRAVY 197


>UniRef50_Q2NFS3 Putative uncharacterized protein n=1 Tax=Methanosphaera stadtmanae
           DSM 3091 RepID=Q2NFS3_METST
          Length = 282

 Score = 91.6 bits (226), Expect = 2e-17,   Method: Composition-based stats.
 Identities = 19/159 (11%), Positives = 48/159 (30%), Gaps = 13/159 (8%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRP-TGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             +   +      + +P        +   P ++ ++G++ + LGI+ DD           
Sbjct: 4   KLIEFNIESSFGCFNKPFSNKGGLLSYNIPPKTSIIGMVCSILGIEFDDYIEKDD----- 58

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
              VR   +           +     V  +R  +      +     ++ L    + + + 
Sbjct: 59  ---VRVYAIEKFYDIKVSVQM--MSKVRSSRIIFNNTSDGDIANIHQDLLIKPKYKIFIS 113

Query: 122 LTPHATMVISELEKAVLK--PRYTPYLGRRSCPLTHPLF 158
                     +    + K    Y  Y+GR   P+++   
Sbjct: 114 FPDTLVEYEKDFINKLKKHETVYNLYMGRNEFPISYEFI 152


>UniRef50_A1HND7 CRISPR-associated protein Cas5 family n=1 Tax=Thermosinus
           carboxydivorans Nor1 RepID=A1HND7_9FIRM
          Length = 257

 Score = 91.6 bits (226), Expect = 2e-17,   Method: Composition-based stats.
 Identities = 37/231 (16%), Positives = 63/231 (27%), Gaps = 29/231 (12%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTR-PTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             L + ++    ++  P     R PT   P  + + G L    G    +  +   L  S 
Sbjct: 6   DVLKIEMSAMTASFRYPHVMIGRLPTFEMPPPATIYGHLCGVWG----EWFNPGDLEFSY 61

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTV---LGAREDYRGLKSHETI----QTWREYLCDA 114
            F                  +   H +    G  E   G              R++L   
Sbjct: 62  VF----------THGGIGEDVELGHMIEFGSGRSEKTLGGLPKNMKGSLNPQRRQFLFRP 111

Query: 115 SFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTH--PLFLGTCQASDPQKALL 172
             T+ L        ++  LE+A   P +   LGR     T     +    QAS    A  
Sbjct: 112 RMTLYL---KGDDKILQRLEQAFKSPAFAYILGRSQDLATVHSITWARLKQASGAFFANT 168

Query: 173 NYEPVGGDIYS--EESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMD 221
                     S          + +    EP+     +   R   +   G++
Sbjct: 169 LLPWTLRQWVSVGRPVYMPKWINYHKLREPVFERYLEIDDRPLRIFGEGVE 219


>UniRef50_B9LWL0 CRISPR-associated protein Cas5, Hmari subtype n=1 Tax=Halorubrum
           lacusprofundi ATCC 49239 RepID=B9LWL0_HALLT
          Length = 265

 Score = 91.3 bits (225), Expect = 2e-17,   Method: Composition-based stats.
 Identities = 30/209 (14%), Positives = 57/209 (27%), Gaps = 15/209 (7%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
           + L L +      + +     T+ T R P R+ + G+L A +G  RD    +     S  
Sbjct: 13  TCLSLTVRSTWGHFKRVGRSVTKQTYRIPPRTTVAGMLAAIVGSDRDSYYDVFGADTS-A 71

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGL-------KSHETIQTWREYLCDAS 115
            A+     I      +     D    +      R            +      E L D  
Sbjct: 72  IAITPLFDIRTVNVPTTGLGTDPKQAVTKTAGSRRSYALTYQDTEGDRQIHAYELLTDPV 131

Query: 116 FTVALWLTPHATMVISELEKAV--LKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLN 173
           + + + +         +LE+ +   +  Y P LG+     T            P +    
Sbjct: 132 YRIDVAV--EDEAYYEKLERRLDNEESYYPPSLGKSEYLCTVE---DVETDVSPTELAEA 186

Query: 174 YEPVGGDIYSEESVTGHHLKFTARDEPMI 202
            +     +           +    D    
Sbjct: 187 EQYDVDSVVPGSLSEVIPQQGVTYDIERS 215


>UniRef50_A7GQ89 CRISPR-associated protein Cas5 family n=1 Tax=Bacillus cytotoxicus
           NVH 391-98 RepID=A7GQ89_BACCN
          Length = 232

 Score = 90.5 bits (223), Expect = 4e-17,   Method: Composition-based stats.
 Identities = 18/150 (12%), Positives = 41/150 (27%), Gaps = 9/150 (6%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              + L+L      + +P       T   P  S + G++   L       + L  L  S+
Sbjct: 1   MKVIRLKLFQETACYTKPFANKVAETYPLPPYSTVKGMIHQLL-----QANELLPLRFSI 55

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQT-WREYLCDASFTVAL 120
           Q       +      +          +          + H T    +   L +    + +
Sbjct: 56  QGNYETKLIDYRKSYMVKKKSVSMPIIFDGLAMEVPEQEHMTSMPLYTHMLFNVELVIHI 115

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRS 150
                   ++  + +  ++      LGR  
Sbjct: 116 A---GEEALLERIYQHFIELNQHLSLGRHE 142


>UniRef50_UPI0001693F6C hypothetical protein Plarl_07470 n=1 Tax=Paenibacillus larvae
           subsp. larvae BRL-230010 RepID=UPI0001693F6C
          Length = 266

 Score = 90.5 bits (223), Expect = 4e-17,   Method: Composition-based stats.
 Identities = 25/173 (14%), Positives = 47/173 (27%), Gaps = 20/173 (11%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRP-TGRFPTRSGLLGLLGACLGIQRDDTS-------- 52
              L   L G    + +P        T     +  L GL GA +G+              
Sbjct: 1   MRALRFELKGETAFFKKPDVNVYAYFTYSHIHKVALYGLFGAIIGLGGYSQQYERNHPLT 60

Query: 53  -------SLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQ 105
                   ++A+        R   + +          +           Y   +    + 
Sbjct: 61  SNRRKNSEIKAVFPEFYEVFRDTSVCIVPHGDRGYFAKKIQIFNNTV-GYASQEVGGVLN 119

Query: 106 TWREYLCDASFTVALWLTPH-ATMVISELEKAVLKPR--YTPYLGRRSCPLTH 155
              ++L    +T+ +         V   L   +L  +  Y PYLG+   P + 
Sbjct: 120 VREQWLEHPHWTIYVAEDEGIPQPVFDRLADYILHSKAEYCPYLGKNDHPASL 172


>UniRef50_C9XLN6 Putative uncharacterized protein n=6 Tax=Clostridium difficile
           RepID=C9XLN6_CLODC
          Length = 268

 Score = 88.9 bits (219), Expect = 1e-16,   Method: Composition-based stats.
 Identities = 19/157 (12%), Positives = 44/157 (28%), Gaps = 11/157 (7%)

Query: 2   RSYLILRLAGPMQAWGQP--TFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSS------ 53
              L  +L  P   +  P         T   P+++ ++G++      + +          
Sbjct: 1   MKVLQCKLKQPTAHYRDPKVFQNEYISTLNLPSKTTIMGMITYLCDRRLNSDIDIGIIGT 60

Query: 54  LQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCD 113
                         D                +       + Y+  K+  +I  + E L +
Sbjct: 61  HHHRELEFSRGENIDFWNEYTNMRKGKDKEKFLLQGNYYDYYKEHKAQNSILNY-EVLKE 119

Query: 114 ASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRS 150
              T+ +         +  ++K +  P     LGR+ 
Sbjct: 120 VELTIFISCKDDEE--LEFIKKKLESPCKYANLGRKE 154


>UniRef50_C8K6I7 Crispr-associated protein cas5 n=1 Tax=Listeria monocytogenes FSL
           R2-503 RepID=C8K6I7_LISMO
          Length = 240

 Score = 88.9 bits (219), Expect = 1e-16,   Method: Composition-based stats.
 Identities = 20/156 (12%), Positives = 43/156 (27%), Gaps = 12/156 (7%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M   + +R+      + +      + +   P  S ++G++    G   D    +    + 
Sbjct: 1   MVRAIRVRIHQDSANYKKKMSFQLKESFPLPPFSTVIGMVHVACGF--DSYHEMDISVQG 58

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
             F    D     +          +H   G     RG             L +    + +
Sbjct: 59  NYFNTFNDLYTRYEFGNKKFEKGRHHINAGGLGVTRG-------VATVNLLNNIDLLIHI 111

Query: 121 WLTPHATMVISELEKAVLK-PRYTPYLGRRSCPLTH 155
              P        +  ++ + P     LGR    +T 
Sbjct: 112 --IPKKEEDFELILNSLRRMPTRFLSLGRHEDLITI 145


>UniRef50_A6UNR9 CRISPR-associated protein Cas5, Hmari subtype n=2 Tax=Methanococcus
           RepID=A6UNR9_METVS
          Length = 225

 Score = 88.6 bits (218), Expect = 2e-16,   Method: Composition-based stats.
 Identities = 25/171 (14%), Positives = 52/171 (30%), Gaps = 19/171 (11%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              ++         + +P    +  T          GL+GA +GI + D   L   ++ +
Sbjct: 1   MKSVVFSAKSEYGRFRKPYTTTSALTFLCIHPVAAKGLIGALVGIDKLD---LYEETKDL 57

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +  +                 +D  +V                 +  E+L    +   + 
Sbjct: 58  KIGIEVL----------GEINKDLQSVKLLNLKEGVSGGMFHFPSNIEFLRCPHYRFYVM 107

Query: 122 LTPHATMVISELEKAVL--KPRYTPYLGRRSCPLTHPLFLGTCQASDPQKA 170
                   ++EL   +   +  +TPYLG          + G  + S  +KA
Sbjct: 108 W---NENKLNELNDKLNVGEWEFTPYLGVSESIAKMN-YEGMFEVSKVEKA 154


>UniRef50_D1B1G1 CRISPR-associated protein Cas5 n=1 Tax=Sulfurospirillum deleyianum
           DSM 6946 RepID=D1B1G1_SULD5
          Length = 237

 Score = 88.2 bits (217), Expect = 2e-16,   Method: Composition-based stats.
 Identities = 25/146 (17%), Positives = 52/146 (35%), Gaps = 16/146 (10%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              +   + G + ++  P F     T   P ++ ++GLL       + +   +    E +
Sbjct: 1   MEAIRFEVEGLLNSFRVPFFRTYHKTFLAPPKTTIIGLLCNIALKSQKEFFEILN-QELI 59

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
             +V  DE+            +D  +     +   G          R+ L  + +T+ L 
Sbjct: 60  DVSVIIDEI--------NGKTKDLWSYKTLEKGNMGK-----SVIRRDKLFLSKYTIYLS 106

Query: 122 LTPHATMVISELEKAVLKPRYTPYLG 147
           +      +  E+  A+  P+ TP LG
Sbjct: 107 IKNK--TLFDEIYSALKNPKNTPALG 130


>UniRef50_C9XPZ9 Putative uncharacterized protein n=5 Tax=Clostridium difficile
           RepID=C9XPZ9_CLODC
          Length = 233

 Score = 88.2 bits (217), Expect = 2e-16,   Method: Composition-based stats.
 Identities = 21/149 (14%), Positives = 44/149 (29%), Gaps = 26/149 (17%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L L L      + +P       T   P  S + GL+   L             +E +
Sbjct: 1   MKVLKLDLFQETACYKKPFAMKITETYPLPPYSTINGLIHKIL-----------NATEYI 49

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
            F +         +    +   +Y T    ++D        +       L + +  + + 
Sbjct: 50  PFNISV-------QGTYESIFNNYQTTYFYKKDSITSMPMNSHM-----LLNVNLIIHI- 96

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRS 150
                  ++ E+  ++L       LGR+ 
Sbjct: 97  --GGDFDLLEEIYDSLLNYDEHLSLGRKE 123


>UniRef50_B8FSG3 CRISPR-associated protein Cas5 n=4 Tax=Firmicutes
           RepID=B8FSG3_DESHD
          Length = 231

 Score = 87.0 bits (214), Expect = 4e-16,   Method: Composition-based stats.
 Identities = 30/196 (15%), Positives = 57/196 (29%), Gaps = 28/196 (14%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L   + G +  + +P    T+ T  F T +   GL+GA LG        ++    + 
Sbjct: 1   MKGLAFDVLGTVGHFRRPDTTATQLTYPFITPTAAKGLVGAILG--------IEDFVTTD 52

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
           +  +     +    +      +D               S     T  E L +  + +   
Sbjct: 53  RVGIELLRPVRTVAQQMSMLGKD-------------PGSTFNRPTTIELLVNPGYRIYYT 99

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASD----PQKALLNYEPV 177
              +   ++  L     +  YT YLG  +  LT P+               K +     V
Sbjct: 100 GEEYTEQLLDFLTG--ERAVYTTYLG-TAYALTKPILYKVYPEVSYPVAEGKEIEMRTVV 156

Query: 178 GGDIYSEESVTGHHLK 193
              +  E  +      
Sbjct: 157 PTALIREIVLKADRYY 172


>UniRef50_A0LM54 Putative uncharacterized protein n=1 Tax=Syntrophobacter
           fumaroxidans MPOB RepID=A0LM54_SYNFM
          Length = 210

 Score = 85.9 bits (211), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 36/182 (19%), Positives = 67/182 (36%), Gaps = 32/182 (17%)

Query: 60  SVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVA 119
           +++  VR D              +D+ T         G  S   + + R +L DA+F V 
Sbjct: 33  ALRMGVRVDR--------EGLLRKDFQTAQNVIVA--GGGSVGDLVSNRYFLSDAAFLVG 82

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFL--GTCQASDPQKALLNYEPV 177
           L       M++  L  ++  PR+  +LGR+S   + P ++  G  + ++   AL ++ P+
Sbjct: 83  LE---GDFMLLHRLHASLAHPRWPVFLGRKSYVPSIPPYIKNGLLEGAELMSALASFTPL 139

Query: 178 ---GGDIYSEESVTG--------------HHLKFTARDEPMITLPRQFASREWYVIKGGM 220
                     + V                       RD+PM     Q    + +V+   +
Sbjct: 140 ISVEELAARRKRVESGRRVERTRFVLESASPTHEIRRDQPMSFALGQRVFHDRFVVTEYL 199

Query: 221 DV 222
           DV
Sbjct: 200 DV 201


>UniRef50_Q2RHQ8 Putative uncharacterized protein n=1 Tax=Moorella thermoacetica
           ATCC 39073 RepID=Q2RHQ8_MOOTA
          Length = 294

 Score = 85.5 bits (210), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 27/157 (17%), Positives = 42/157 (26%), Gaps = 14/157 (8%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
             L L        +   +    R T   P  S ++GLL   LG  R    ++  L+  + 
Sbjct: 10  RVLKLGFTAASAHFRVTSSNNPRKTYPLPPYSTVIGLLANILG-DRAKIEAM--LAGGLA 66

Query: 63  FAV------RCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASF 116
             V         E               +++    R                E L D   
Sbjct: 67  LGVLAQHNYITKEYTWLRNMSPSAHKGRFYSYDNRRWQETPEHPGGQSPVVVEVLNDVK- 125

Query: 117 TVALWLTPHATMVISELEKAVLKPRY---TPYLGRRS 150
            V ++L      V   L +    P       +LGR  
Sbjct: 126 -VYVYLYHPNEQVTGFLMENACLPERWLSHLHLGRAE 161


>UniRef50_D1QSA9 CRISPR-associated protein Cas5, Tneap subtype n=1 Tax=Prevotella
           oris F0302 RepID=D1QSA9_9BACT
          Length = 224

 Score = 85.1 bits (209), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 26/157 (16%), Positives = 50/157 (31%), Gaps = 27/157 (17%)

Query: 2   RSYLILRLAGPMQAWGQPTFEG-TRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
                ++++    ++  P      +PT   P  S +LGL+ AC G       +   +   
Sbjct: 1   MKVFRIKISAWTASFRYPNIISGYQPTLEVPPLSTILGLMNACAGR----YLNHADMEIG 56

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRG-LKSHETIQTWREYLCDASFTVA 119
             F  R             +   D  T+   + D     K  ++    R++L D +  + 
Sbjct: 57  YYFNYR-------------SISNDLETIYQMKYDKGTAKKQVKSNVINRQFLFDNTLYIY 103

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHP 156
           +        +  +  K    P +   LGR     T  
Sbjct: 104 I--------IDKDFVKYFQTPAFQILLGRSCDLATIE 132


>UniRef50_B1I4M5 CRISPR-associated protein Cas5 family n=1 Tax=Candidatus
           Desulforudis audaxviator MP104C RepID=B1I4M5_DESAP
          Length = 255

 Score = 82.4 bits (202), Expect = 1e-14,   Method: Composition-based stats.
 Identities = 25/185 (13%), Positives = 61/185 (32%), Gaps = 31/185 (16%)

Query: 2   RSYLILRLAGPMQAWGQPTF-EGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
                + +  P+ ++  P F  G + +   P  S + G + + +G    +  +   +  +
Sbjct: 1   MRVAKVHIEAPIASFRYPHFLIGRQTSFDMPPPSTIYGHIASAVG----EWFNPATVKFA 56

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTW-------REYLCD 113
            QF+           +   + L   H +    + ++  +    + T        R++L  
Sbjct: 57  YQFS----------FQAKGSDLEHQHVITKGGQTFKWGERKYPVSTQAVVQPHLRDFLFG 106

Query: 114 ASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLN 173
              T+ L+          +L +A   P +   LGR     +    +   +    + A L 
Sbjct: 107 CRLTLYLYPP--------DLAEAFRNPVFCVILGRSQDLASI-TSVEVIELEKAKGAYLE 157

Query: 174 YEPVG 178
              + 
Sbjct: 158 QTLLP 162


>UniRef50_B0M916 Putative uncharacterized protein n=4 Tax=Firmicutes
           RepID=B0M916_9FIRM
          Length = 252

 Score = 82.4 bits (202), Expect = 1e-14,   Method: Composition-based stats.
 Identities = 24/178 (13%), Positives = 53/178 (29%), Gaps = 17/178 (9%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRP-TGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
                + L G    + +P        T     +  LLG+ GA LG    ++   +   + 
Sbjct: 1   MEVCKVTLKGRTAFFKKPDVNSYYYFTYGQIHKVVLLGIFGAILGYSGYESIKTEKRKKD 60

Query: 61  VQFA---------VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYL 111
                        ++     +  +       +           Y   +    +    ++L
Sbjct: 61  SAEGPGFPEFYERLKDCRFSIVPKNEKGWIPKKIQ-YFNNSVGYASREQGGNLIIKEQWL 119

Query: 112 CDASFTVALWLTPHATMVISELEKAV--LKPRYTPYLGRRSCPLTHPLFLGTCQASDP 167
               + + + L    +    +L +A+      Y+PYLG+   P    L     +A + 
Sbjct: 120 ESPEWDIFILLDGEESR---KLSEALMDRCCVYSPYLGKNDHPADL-LNPDIIEAEEV 173


>UniRef50_Q3M7D6 Fruiting body developmental protein S-like protein n=3
           Tax=Cyanobacteria RepID=Q3M7D6_ANAVT
          Length = 210

 Score = 81.6 bits (200), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 24/153 (15%), Positives = 50/153 (32%), Gaps = 22/153 (14%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + + L++  P+  + Q        T   P  S + G+L + +G    +    +     +
Sbjct: 1   MTTIALKVEVPIACFRQSRAREYGETYPVPPPSTVYGMLLSLVG----EVDRYKHCGVKL 56

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
             A+              T +R +H      +      S      ++E L +  F V + 
Sbjct: 57  AIAL-------LSEPEKSTVIRTFH----RFKTKNIHDSKNNKPDYQELLTNIEFIVWVD 105

Query: 122 LTPH--ATMVISELEKAVLKP----RY-TPYLG 147
                    ++  L +A+  P    R+    LG
Sbjct: 106 AGVDKAKPNLVERLAEALTNPASINRFGGLCLG 138


>UniRef50_A9WFZ3 CRISPR-associated protein Cas5 family n=6 Tax=Chloroflexi (class)
           RepID=A9WFZ3_CHLAA
          Length = 252

 Score = 81.6 bits (200), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 33/213 (15%), Positives = 58/213 (27%), Gaps = 32/213 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFE-GTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
              L + L     ++  P F  G +P+   P  + + G + + LG    D      L+ +
Sbjct: 8   MQALKIVLEALTTSFRYPHFMLGVQPSFPLPPPATIYGHICSALG----DWVDPAGLAFA 63

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSH----ETIQTWREYLCDASF 116
             F                  L   H +  +     G +            R+ L     
Sbjct: 64  YHF----------TAAGEGHDLEHIHVLSASSGKLPGGEPKVLEGNINPFKRQLLLFPRL 113

Query: 117 TVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTH----PLFLGTCQASDPQKALL 172
           T+ L           E   A   PRY   LGR      +     + L        +  LL
Sbjct: 114 TLYLNRP--------EWIDAFRFPRYPVVLGRSQDLAAYTHIDIVDLQQADQVYFEHTLL 165

Query: 173 NYEPVGGDIYSEESVTGHHLKFTARDEPMITLP 205
            +           ++    + +  R +P     
Sbjct: 166 PFAMATQAPAGVVTLMPRWINYRQRRQP-SFAR 197


>UniRef50_A1ZVP9 Crispr-associated protein Cas5, tneap subtype n=1 Tax=Microscilla
           marina ATCC 23134 RepID=A1ZVP9_9SPHI
          Length = 218

 Score = 80.1 bits (196), Expect = 6e-14,   Method: Composition-based stats.
 Identities = 25/156 (16%), Positives = 45/156 (28%), Gaps = 27/156 (17%)

Query: 2   RSYLILRLAGPMQAWGQP-TFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
                + +     ++  P    G +PT   P  S +LGL+ A  G       +   L   
Sbjct: 1   MRVFKIDITSWTASFRYPNLISGFQPTLEVPPVSTVLGLINAAAGH----YVAHSTLKLG 56

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTV-LGAREDYRGLKSHETIQTWREYLCDASFTVA 119
             F  +             +   D  T+              ++    RE+L +A   + 
Sbjct: 57  YYFEYQ-------------SKAVDLETIYQIGAHKGMPSNHAKSNIIRREFLFEAFLRLY 103

Query: 120 LWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTH 155
           +           E+      P Y   LGR +   + 
Sbjct: 104 VTS--------QEVADYFRSPVYPIVLGRMNDLASI 131


>UniRef50_C1DUL8 Crispr-associated protein Cas5, tneap subtype n=2 Tax=Aquificales
           RepID=C1DUL8_SULAA
          Length = 236

 Score = 80.1 bits (196), Expect = 6e-14,   Method: Composition-based stats.
 Identities = 22/154 (14%), Positives = 46/154 (29%), Gaps = 23/154 (14%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L ++       + +P       +   P  S + G     +G+  +    +    +  
Sbjct: 1   MKLLKIKAYQIFANYRKPMSFNFWDSYPLPPLSTVRGWFHTTIGV--NQYIPIAMSIQGK 58

Query: 62  QFAVRCD-----ELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASF 116
             +V  D     +      +     L  ++ V                 T+   + D S 
Sbjct: 59  FSSVVHDLQTLIKFDRKRDKERGIFLEGFNKVFSK------------SPTYVVNIYDISL 106

Query: 117 TVALWLTPHATMVISELEKAVLKPRYTPYLGRRS 150
           T+ L         +   ++ +LK  Y P LGR+ 
Sbjct: 107 TIYLKA---KEEYLKLFKENLLKNEY-PSLGRKE 136


>UniRef50_A6LJX1 CRISPR-associated protein Cas5 n=1 Tax=Thermosipho melanesiensis
           BI429 RepID=A6LJX1_THEM4
          Length = 253

 Score = 80.1 bits (196), Expect = 6e-14,   Method: Composition-based stats.
 Identities = 29/233 (12%), Positives = 66/233 (28%), Gaps = 20/233 (8%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRP-TGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
                  L G M  + +     T   T  F  +  L G+ GA LG++           E 
Sbjct: 1   MKAFSFELKGDMGFFKKNDTNATVYATYNFIHKLNLFGIFGAILGLEGYKRDKSGNFMEY 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDAS-FTVA 119
            +   +     +    +     +    +      +   ++   +Q   + + ++  + + 
Sbjct: 61  YE---KFKNFKVAITPLYNKPPKKTLVIFNNSTGHASREAGGVLQIKEQVIVESIGYRIF 117

Query: 120 L----WLTPHATMVISELEKAVLK--PRYTPYLGRRSCPLTHPLFLGT-CQASDPQKALL 172
           +      T     V  +LEK V K    Y  Y G+         +     +  + +++ +
Sbjct: 118 IPCLETFTDEEKNVYEKLEKMVKKNYSEYPIYFGKNEFLAYFENYCSIELERLEFEESTV 177

Query: 173 NYEPVGGDIYSEESV--------TGHHLKFTARDEPMITLPRQFASREWYVIK 217
           N      DI   +                    + P          ++ +V  
Sbjct: 178 NSLVRLKDIEFFKENLDDIELFEEETDYISILEELPYDFNENHLYLKDVFVFT 230


>UniRef50_D1A6P6 Metal dependent phosphohydrolase n=1 Tax=Thermomonospora curvata
           DSM 43183 RepID=D1A6P6_THECD
          Length = 1027

 Score = 79.7 bits (195), Expect = 6e-14,   Method: Composition-based stats.
 Identities = 24/153 (15%), Positives = 41/153 (26%), Gaps = 26/153 (16%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
             + ++L  P+ ++  P F G       P  S L G+L A  G                 
Sbjct: 9   EAVRVQLYAPVASFRDPMFPGVTRCLPVPPPSTLRGMLAAATGRP--------------- 53

Query: 63  FAVRCDELILDDRRVSVTGLRDYH-TVLGAREDYRGLK----SHETIQTWREYLCDASFT 117
            A      +             YH           G +            R +L     T
Sbjct: 54  -AEPVVLGVCAYAEGRGVDTETYHPIAADGSNPAIGGRVRPGKGGMTIRERPFLTGVHIT 112

Query: 118 VALWLTPHATMVISELEKAVLKPRYTPYLGRRS 150
           + + +          +  A+ +P +   LGR  
Sbjct: 113 LWVPMPDG-----ERIATALRRPTWGLRLGRSQ 140


>UniRef50_Q0ATZ7 CRISPR-associated protein, Cas5h family n=1 Tax=Syntrophomonas
           wolfei subsp. wolfei str. Goettingen RepID=Q0ATZ7_SYNWW
          Length = 231

 Score = 78.2 bits (191), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 24/163 (14%), Positives = 53/163 (32%), Gaps = 22/163 (13%)

Query: 13  MQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSE-----SVQFAVRC 67
           M  + +P    +  +  FP  + + GL+   +GI  + +   +          VQ A+  
Sbjct: 1   MALFRKPYTTTSMVSYPFPPPTAIAGLIAGIIGINHEASQDAKNARYWEKMREVQVAIAL 60

Query: 68  DELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPHAT 127
              I                V   +         E IQ   + +    + + +       
Sbjct: 61  LSPIRWINTA----------VNLMKYKNSNADMSEHIQVKHQLVKKPRYRIYVQGG---- 106

Query: 128 MVISELEKAVLK--PRYTPYLGRRSCPLTHPLFLGTCQASDPQ 168
            +   L++ + +    YTP LG  +  L    + G  + ++ +
Sbjct: 107 EIYKILKQRLEREEFIYTPCLG-AAYALADIKYHGEYEPAEAE 148


>UniRef50_B5YL08 CRISPR-associated protein Cas5 n=1 Tax=Thermodesulfovibrio
           yellowstonii DSM 11347 RepID=B5YL08_THEYD
          Length = 257

 Score = 77.4 bits (189), Expect = 3e-13,   Method: Composition-based stats.
 Identities = 23/158 (14%), Positives = 55/158 (34%), Gaps = 15/158 (9%)

Query: 2   RSYLILRLA-GPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
              L+  +    + +   P    +  T   P  S ++G+L   L   ++D   LQ L + 
Sbjct: 1   MKALVFHIRLNSLYSIRIPFTWQSALTYPVPPPSAVIGMLANALQRYKNDRHPLQYLEK- 59

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFT--V 118
               +  + +    + +S   ++ Y T     +    +    T    R++    ++   +
Sbjct: 60  ----IENELIWAGSKLLSPCIIKSY-TTSAIVKWDDTMPWKFTNAIGRQF----AYAQQI 110

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHP 156
            +        +++E+ KA+         G    P+T  
Sbjct: 111 QIATIFKDESIVNEIVKALK--ISPLTCGDSESPITIE 146


>UniRef50_C6A4J5 Putative uncharacterized protein n=1 Tax=Thermococcus sibiricus MM
           739 RepID=C6A4J5_THESM
          Length = 218

 Score = 75.8 bits (185), Expect = 9e-13,   Method: Composition-based stats.
 Identities = 24/199 (12%), Positives = 53/199 (26%), Gaps = 21/199 (10%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M   + + +   +  +   T    R +   P  + +LG   + LG  R+       L E 
Sbjct: 1   MEKGVTIDVLFDLAHFKVHTTMKGRTSYLIPLPTTVLGFFFSILGKGREAY-----LRER 55

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
            QF     +       +      +   +   R                  L    +  A+
Sbjct: 56  NQF-----KAGAKLLSIKGIARENAQLLKLKRGQEVRTTEELM------LLVKPKYRFAI 104

Query: 121 WLTPHATMVISELEKAVL--KPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVG 178
           W       +I+ L + V      + PY G     ++           + +  + +     
Sbjct: 105 W---GKQELINNLYERVRTFDFEFVPYGGISEFIISEIETPQLYDEYEEKDTIKDSYVPQ 161

Query: 179 GDIYSEESVTGHHLKFTAR 197
             + S   +    +     
Sbjct: 162 PLLNSLRILDNGIVYNLPY 180


>UniRef50_A8TI38 CRISPR-associated protein Cas5 family n=1 Tax=Methanococcus voltae
           A3 RepID=A8TI38_METVO
          Length = 248

 Score = 74.3 bits (181), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 30/197 (15%), Positives = 57/197 (28%), Gaps = 26/197 (13%)

Query: 2   RSYLILRLAGPMQAWGQPTFEG-TRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
              L ++       +  P     T  +   P  S ++G++ +C+G +     +      S
Sbjct: 1   MKLLHVQFQAYTATFKMPNINSGTMVSIPVPLYSTIVGIISSCMGRELQRDETKIGFKYS 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
                                L   H      +     ++ E   T RE+       + L
Sbjct: 61  Y--------------ENKGKDLETTH--RLKYDGGLLKQNSENSVTAREFHIKPILDIYL 104

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGD 180
                       L++  L P +TP LGR          +    A +     +    V  D
Sbjct: 105 SNLN--------LKEYFLNPVWTPSLGRSQDVA-WITKIEEIDAENITNGKIKATLVPID 155

Query: 181 IYSEESVTGHHLKFTAR 197
               ++V G  ++ T  
Sbjct: 156 SLKGKTVPGRLIQATDY 172


>UniRef50_D2QHQ8 CRISPR-associated protein Cas5, Hmari subtype n=1 Tax=Spirosoma
           linguale DSM 74 RepID=D2QHQ8_9SPHI
          Length = 266

 Score = 73.5 bits (179), Expect = 4e-12,   Method: Composition-based stats.
 Identities = 22/158 (13%), Positives = 47/158 (29%), Gaps = 17/158 (10%)

Query: 3   SYLILRLAGPMQAWGQPTFEG-TRPTGRFPTRSGLLGLLGACLGIQ----RDDTSSLQAL 57
             L   L      + +P      + +     +  LLG++GA  G++    +        L
Sbjct: 13  ELLSFDLQADFGFFRKPDVNEGIQYSYNMLHKPALLGIMGAIAGLKGHQQKGQWPQYYTL 72

Query: 58  SESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFT 117
            +SV   +              +  +     +          +  T+      L   ++ 
Sbjct: 73  LKSVLVGI------APLNHERGSFTK---VAITYTNTVGYANADGTLIVHENTLRCPAYR 123

Query: 118 VALWLTPHATMVISELEKAVL--KPRYTPYLGRRSCPL 153
           V + L      + S L   +   +  + PYLG+     
Sbjct: 124 VFVLLDQADE-LQSRLAARIRQHEAEFIPYLGKNEFTA 160


>UniRef50_B9L1B8 CRISPR-associated protein Cas5, Tneap subtype n=1
           Tax=Thermomicrobium roseum DSM 5159 RepID=B9L1B8_THERP
          Length = 235

 Score = 73.2 bits (178), Expect = 6e-12,   Method: Composition-based stats.
 Identities = 34/204 (16%), Positives = 63/204 (30%), Gaps = 31/204 (15%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
            + +RL     ++  P+F   + +   P  + + GLL A  G        +  L+  + +
Sbjct: 5   AVRIRLTALTASFRAPSFVAYQLSLAVPPLATIFGLLSAARG-HWVMPHEVPWLAYRLTY 63

Query: 64  AVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLT 123
           A R  +L                     ++     +  E     RE+L      + L   
Sbjct: 64  AARAMDLEAIYSVER-------------KDAADTPRFKERNIVQREFLVSPELDLFLPAE 110

Query: 124 PHATMVISELEKAVLKPRYTPYLGRRSCPLTH-PLFLGTCQASDPQKALLNYEPVGGDIY 182
                         L+PRY   LGR     T   +   + +            PV G + 
Sbjct: 111 WRDP---------FLRPRYQLVLGRSQDLATVSSIGPASLEPVS-------TGPVTGVLL 154

Query: 183 SEESVTGHHLKFTARDEPMITLPR 206
             E V  + +    ++ P+   P 
Sbjct: 155 PAEVVARNGVTAVLQNLPVAFTPD 178


>UniRef50_B3EG03 CRISPR-associated protein Cas5 family n=4 Tax=cellular organisms
           RepID=B3EG03_CHLL2
          Length = 206

 Score = 72.0 bits (175), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 24/149 (16%), Positives = 40/149 (26%), Gaps = 31/149 (20%)

Query: 2   RSYLILRLAGPMQAWGQP-TFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
              L +++     ++  P    G +PT   P  S + GL+ A  G               
Sbjct: 1   MKLLRIKIRSWTASFRYPIFVAGFQPTLPMPPLSTIYGLISAAKG--------------- 45

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
                  +  +            D  T+                   RE+L D    + L
Sbjct: 46  -NIVTPEETSVGYVFSYQ-AKAVDLETIYEIEGLKAKSN-----VANREFLFDNELYLYL 98

Query: 121 WLTPHATMVISELEKAVLKPRYTPYLGRR 149
                      +LE    +P +   LGR 
Sbjct: 99  TNL--------DLESVFRRPHHPILLGRS 119


>UniRef50_B6WA84 Putative uncharacterized protein n=2 Tax=Anaerococcus
           RepID=B6WA84_9FIRM
          Length = 245

 Score = 72.0 bits (175), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 30/186 (16%), Positives = 61/186 (32%), Gaps = 9/186 (4%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGT-RPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
              L  RL+G    + QP        T     R  LLGLLGA LG +  +    +   E 
Sbjct: 1   MKALRFRLSGKTGFFKQPDVNTYLYYTYGQIHRVALLGLLGATLGYKGYNEKDREKYPEF 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
            +  +R  ++ +     +    R           +   +    +   + +L + S+ + +
Sbjct: 61  YK-KLRDLKISVVSEGNNGVFDRKLQ-AFNNSTAFASNEEGGNLIVKQVWLENPSWLIYI 118

Query: 121 WLTPHATMVISELEKAV--LKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVG 178
            L    + +   +++ +   K  +TPYLG                     + +++     
Sbjct: 119 LLDNDQSEL---IKEYILDKKTTFTPYLGTNDHMANIS-DCEIVDIEKSDENIIDSLFWS 174

Query: 179 GDIYSE 184
            D    
Sbjct: 175 DDFKLR 180


>UniRef50_B7IEF3 Cas crispr-associated protein Cas5 n=1 Tax=Thermosipho africanus
           TCF52B RepID=B7IEF3_THEAB
          Length = 257

 Score = 71.6 bits (174), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 23/188 (12%), Positives = 57/188 (30%), Gaps = 12/188 (6%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTR-PTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
                  +   M  + +         T  F  +  +LG+ GA LG    D        E 
Sbjct: 1   MKAFCFNIKADMGFFKKNDSNARVFTTYNFIHKPAVLGIFGAILGYSGYDRDRKNNGIEY 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDAS-FTVA 119
            +   +     +  + +    L+    V          ++   +Q   + + ++  +T+ 
Sbjct: 61  YE---KLKNFKIAIKPLYKKPLKKTVVVFNNSSGLASEETGGVLQAKEQVIVESLGYTIF 117

Query: 120 L----WLTPHATMVISELEKAVLK--PRYTPYLGRRSCPLTHPLFLGT-CQASDPQKALL 172
           +      +     +  +LE  V      Y  Y G+         +     +  + ++A++
Sbjct: 118 VPFFETFSEAEKKIYEKLEYMVKNKYAEYPIYFGKNEFFAYFENYRSLNVEELERKEAVV 177

Query: 173 NYEPVGGD 180
           +      D
Sbjct: 178 DSLVKMKD 185


>UniRef50_C0QHV7 Putative CRISPR-associated protein Cas5 n=1 Tax=Desulfobacterium
           autotrophicum HRM2 RepID=C0QHV7_DESAH
          Length = 280

 Score = 71.2 bits (173), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 24/198 (12%), Positives = 45/198 (22%), Gaps = 59/198 (29%)

Query: 15  AWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDT---SSLQALSESVQFAVRCDELI 71
            +  P       T   P ++ + G+L A LGI  +D            S+       +  
Sbjct: 1   MFRDPLTITQNMTFPIPPKTTVGGMLAAILGIDYNDYLNDPEFFNFRYSLVLEKPVRKKS 60

Query: 72  LDDRRVS-------------------VTGLRDYHTVLGAREDYRGLKSHE---------- 102
                V+                       +D        E+   L   E          
Sbjct: 61  FVQNYVANYTKGSEKKFNAIKKYLESGKKQKDLLFEKEQLEEESDLTKKEEKLLGSIGGK 120

Query: 103 -------------------------TIQTWREYLCDASFTVALWLTPHATMVISELEKAV 137
                                        +RE L    + V +    +   ++  LE   
Sbjct: 121 IESESMTLEKASASCSKVFNESFTSPKPIFRELLVAPEYLVFIHDFKYEKEILHSLENHF 180

Query: 138 LKPRYTPYLGRRSCPLTH 155
               ++ Y+G       +
Sbjct: 181 --SEFSLYMGNSEFSANY 196


>UniRef50_C5U6V3 CRISPR-associated protein Cas5 family n=6 Tax=Euryarchaeota
           RepID=C5U6V3_9EURY
          Length = 215

 Score = 71.2 bits (173), Expect = 3e-11,   Method: Composition-based stats.
 Identities = 36/198 (18%), Positives = 56/198 (28%), Gaps = 34/198 (17%)

Query: 4   YLILRLAGPMQAWGQPTFEG-TRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
            + ++L      +  PTF+   +PT   P  S +LGLL A  G        +  L +   
Sbjct: 1   MIRVKLKSWTATFRYPTFQSGYQPTLPLPPISTILGLLSAAKG-------EIVNLEDVEF 53

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWL 122
           F                  L                   +T    RE+L +   T+ L+L
Sbjct: 54  FGYIFKSEGKGVDLEKTYYL-------------SNENEVKTDVIRREFLFNN--TLYLYL 98

Query: 123 TPHATMVISELEKAVLKPRYTPYLGRRSCPLTHP----LFLGTCQASDPQKALLNYEPVG 178
                      +     PRY   LGR     T      + L   +       +L  E   
Sbjct: 99  PDGW-------KTYFKSPRYQLLLGRSCDIATVEEIKKINLEMKREVPIGGTILPLEANV 151

Query: 179 GDIYSEESVTGHHLKFTA 196
             +     V   + K   
Sbjct: 152 PGMILALPVEFDYSKIPR 169


>UniRef50_C9XQW2 Crispr-associated protein cas5 family n=2 Tax=Clostridium difficile
           RepID=C9XQW2_CLODC
          Length = 215

 Score = 70.5 bits (171), Expect = 4e-11,   Method: Composition-based stats.
 Identities = 21/153 (13%), Positives = 41/153 (26%), Gaps = 35/153 (22%)

Query: 6   ILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAV 65
            + + G M  +  P     + T   P  S ++G+L    G + DD          + + +
Sbjct: 5   KIEIIGDMAHFKIPMHSKIQRTYEIPPISTVVGILKNIYGEEIDDF--------ILGYVI 56

Query: 66  RCDELILDDRRVSVTGLRDYHTVLGAREDYRG----LKSHETIQTWREYLCDASFTVALW 121
             D              +D  T+                 +T     EYL +    +   
Sbjct: 57  YHD-----------GTFKDLQTIYKEINPNVKTLTDSDRFQTDVCPIEYLINPKLIIYTN 105

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLT 154
           +  +                    LG+ +C   
Sbjct: 106 IDKNIEFN------------EPLCLGKTNCLAK 126


>UniRef50_B1I5P1 CRISPR-associated protein Cas5 n=2 Tax=Clostridia
           RepID=B1I5P1_DESAP
          Length = 238

 Score = 67.0 bits (162), Expect = 5e-10,   Method: Composition-based stats.
 Identities = 43/213 (20%), Positives = 71/213 (33%), Gaps = 38/213 (17%)

Query: 13  MQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDD-TSSLQALSESVQFAVRCDELI 71
           M ++ +P     + T   P  + L GL GA  G+  ++       L + +         +
Sbjct: 1   MASFRRPLDHNYQRTLPLPPPTTLFGLAGAARGLAEEELWQEASPLRDLL---------V 51

Query: 72  LDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPHATMVIS 131
                      RD  TV+  + +    +S      +RE L +A F +   L      +++
Sbjct: 52  ATLALQKPGLARDMWTVMKIKNNKLAERSPY----FREILFNARFMI---LYGGPEELLA 104

Query: 132 ELEKAVLKPRYTPYLGRRSCP------------LTHPLFLGTCQASDPQKALLNYEPVGG 179
           EL++A L P Y   LGR                   PLF GT    D Q     + P  G
Sbjct: 105 ELQQAFLDPTYPLSLGREDELIVVEELGRGETCPGAPLFSGTVIPGDLQGLRFKWVPRPG 164

Query: 180 DIYSEESVTGHHLKFTARDEPMITLPRQFASRE 212
             +   +V            P+     +   R 
Sbjct: 165 IAFEPPAVET---------MPLAFEVDKRGIRY 188


>UniRef50_C0QR10 Crispr-associated protein Cas5, tneap subtype n=3
           Tax=Hydrogenothermaceae RepID=C0QR10_PERMH
          Length = 253

 Score = 66.2 bits (160), Expect = 7e-10,   Method: Composition-based stats.
 Identities = 16/147 (10%), Positives = 40/147 (27%), Gaps = 7/147 (4%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L ++       + +P       +   P  S + G     +     D +        +
Sbjct: 14  MKILRIKAYQLFANYRKPMSYNYWDSYPLPPLSTIRGWFHYVVWNGNKDENRHY---IPI 70

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
             +++     +     ++          G        K+     T+   + D +  + + 
Sbjct: 71  SMSIQGKFSSVIQDLQTLIKFDRKRNTKGEIVIEGFNKAFSKSPTYVTNIFDINLHIYIK 130

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGR 148
                   +    + V K  Y P +GR
Sbjct: 131 A---EEHFLHRFIENVFKLEY-PSIGR 153


>UniRef50_B4U1Q4 CRISPR-associated protein Cas5, Dvulg subtype n=12
           Tax=Streptococcus RepID=B4U1Q4_STREM
          Length = 239

 Score = 65.1 bits (157), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 38/223 (17%), Positives = 68/223 (30%), Gaps = 52/223 (23%)

Query: 7   LRLAGPMQAWGQPTF--EGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           +R+ G +  +  P       R +   PTR  L G++ A            +    +V   
Sbjct: 1   MRVRGDIALFTNPATKGSSERSSYPVPTRQALQGIVDAVY---------HKPTITNVVTE 51

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV---ALW 121
           V+    I  +   +   L+DY                    ++  YL D  + +    +W
Sbjct: 52  VKVINQIQTELHGTRALLKDY----------------GADLSYVSYLSDVEYLIKYHFVW 95

Query: 122 LTPHATMVISEL--------EKAVLK-PRYTPYLGRRSCPLTHPLFLGTCQASDPQ--KA 170
                 +V   L        E+++ K  R   +LG R C       LG  +A   +  + 
Sbjct: 96  NENRPDLVKDRLPNKHEAIMERSLRKGGRRDVFLGTREC-------LGLVEAISQEEYET 148

Query: 171 LLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREW 213
                           +       T R EP+    R + +R  
Sbjct: 149 AQIASEHANQEIDLGIMFHSFAYPTDRKEPL----RSYFTRTV 187


>UniRef50_B5YAX9 CRISPR-associated protein Cas5, Tneap subtype n=1 Tax=Dictyoglomus
           thermophilum H-6-12 RepID=B5YAX9_DICT6
          Length = 233

 Score = 64.3 bits (155), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 27/227 (11%), Positives = 65/227 (28%), Gaps = 18/227 (7%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              L L++      + +P       T   PT S + G +   L  Q  +   L    +  
Sbjct: 1   MKVLKLKVYQQFANYRKPLSYSFIDTFPLPTYSNIRGWIHRILQAQ--EYIPLSISIQGT 58

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
             ++  D              +D   +   ++             +   L + S  + + 
Sbjct: 59  YESIVYDLQTFYKFDRPRPEKKDLIFLPEYKKTIVKSPF------YVANLQNVSLILHIN 112

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
           +      ++ +++  +L     P +GR          +   +       +  Y+      
Sbjct: 113 M---EYSLLEKIKTMLLDT--FPSIGRHEDMARID-KIDFVEVKRKDIGIDFYKIKYPIY 166

Query: 182 YSEESVTGHHLKFTARDEP----MITLPRQFASREWYVIKGGMDVSQ 224
             +E+   ++L       P    +    R F   +   I+ G    +
Sbjct: 167 LKKETADKYNLIGINFKIPFKYRIEENLRYFEKIDVVYIEEGTLFGE 213


>UniRef50_UPI0001C41C2E CRISPR-associated protein Cas5 Hmari subtype n=1
           Tax=Methanobrevibacter ruminantium M1
           RepID=UPI0001C41C2E
          Length = 287

 Score = 63.5 bits (153), Expect = 5e-09,   Method: Composition-based stats.
 Identities = 21/167 (12%), Positives = 49/167 (29%), Gaps = 16/167 (9%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTR-PTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
              + + +      + +         T   P ++ ++G++GA LG   +D       +++
Sbjct: 1   MKIIEVDIWSSFGCFSKHFSNTGGVLTHLIPPKTSIIGIIGAILGYDVNDYEDNDDGTKT 60

Query: 61  VQF----AVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASF 116
            +      ++     L + +        ++ V G   D             ++ L    +
Sbjct: 61  YKIESLNNIKVSIYPLFEFKTKRVI---FNLVSGTNLDLDIKN------INQDVLISPRY 111

Query: 117 TVALWLTPHATMVISELEKAVLK--PRYTPYLGRRSCPLTHPLFLGT 161
            + +        V       V      Y  Y+GR   PL        
Sbjct: 112 KLFISFPSELDEVEELFLNRVKNNKTIYNLYMGRNEFPLNLEFVREI 158


>UniRef50_C6PRK1 CRISPR-associated protein Cas5 n=1 Tax=Clostridium carboxidivorans
           P7 RepID=C6PRK1_9CLOT
          Length = 220

 Score = 62.8 bits (151), Expect = 8e-09,   Method: Composition-based stats.
 Identities = 15/152 (9%), Positives = 37/152 (24%), Gaps = 23/152 (15%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
                + +      + +P     + T   P  S ++G++         D           
Sbjct: 1   MELRKIEIVSDFAHFKKPFATKQQFTYTIPPISTVIGIIQNLFHEGISDF---------- 50

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
            F        +      +    +++T        +      +      YL ++   +   
Sbjct: 51  VFGFTFKYDEIFKDIQKIYKEVNFNTRKERERYNKNGVWT-SDVCEIHYLVNSKLVIY-- 107

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPL 153
                 + I+E             LG+  C  
Sbjct: 108 TDIEDELKINE----------CLNLGKTDCLA 129


>UniRef50_B7JW17 CRISPR-associated protein DevS n=2 Tax=Cyanobacteria
           RepID=B7JW17_CYAP8
          Length = 212

 Score = 59.7 bits (143), Expect = 8e-08,   Method: Composition-based stats.
 Identities = 19/157 (12%), Positives = 45/157 (28%), Gaps = 22/157 (14%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M + L++ L  P   + +        T   P  + + G+L + +G    +T   +     
Sbjct: 1   MNTPLVIYLDVPFVTFREFHAREMGRTYPVPPPATVYGMLLSLVG----ETDVYRHCGVE 56

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
           +  A       +         LR         +      +     +++E L +    + +
Sbjct: 57  LAIA-------MLSEAKKSRILRQM----RRFKQKDFSHAENVNPSYQEILSNLKCLIWV 105

Query: 121 WLTPH--ATMVISELEKAVLKPRY-----TPYLGRRS 150
                     +   +E    +P         +LG   
Sbjct: 106 RSEAEMMQPSLKERIEFTFERPELVRRFGCLFLGESD 142


>UniRef50_A0Q255 Putative uncharacterized protein n=4 Tax=Bacteria
           RepID=A0Q255_CLONN
          Length = 212

 Score = 55.8 bits (133), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 10/109 (9%), Positives = 29/109 (26%), Gaps = 13/109 (11%)

Query: 51  TSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREY 110
                   + ++  +                L+   T   +   Y   +    +    ++
Sbjct: 23  YPEFYEKLKDIKIGI-------VPINEHGYNLKKVQTFNNSV-GYASQEKGGNLIVKEQW 74

Query: 111 LCDASFTVALWLTPHATMVISELEKAVLK--PRYTPYLGRRSCPLTHPL 157
           L    + + + +      +  +L   +     +Y PYLG+         
Sbjct: 75  LEKPKWEIYILI---ENEITEQLADRLKNYRFKYIPYLGKNDHLADISF 120


>UniRef50_C2HJA9 Putative uncharacterized protein n=1 Tax=Finegoldia magna ATCC
          53516 RepID=C2HJA9_PEPMA
          Length = 361

 Score = 55.8 bits (133), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 7/45 (15%), Positives = 15/45 (33%)

Query: 2  RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGI 46
             L +++     ++ +        T   P  S ++G L    G 
Sbjct: 1  MKILRIKIKQAQASYTREETVDNHTTYPLPPFSTIIGALHNACGY 45


>UniRef50_C6DXZ6 Crispr-associated protein Cas5 n=2 Tax=root RepID=C6DXZ6_CLOBO
          Length = 214

 Score = 53.1 bits (126), Expect = 7e-06,   Method: Composition-based stats.
 Identities = 22/183 (12%), Positives = 49/183 (26%), Gaps = 37/183 (20%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             +  + L   M  +        + T   P  S ++G+L    G +              
Sbjct: 1   MEFSKVILTSTMAHFKYGINGKNQNTFTVPPISTIVGILKNVYGKE-------------- 46

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHET---IQTWREYLCDASFTV 118
                  + I           +D  T+         L   +       + EYL + + T+
Sbjct: 47  -----IKDFIFGYICRYEDIFKDVITIYKEVNLNITLTKGDRFQHDIGFIEYLVNPTITI 101

Query: 119 ALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVG 178
              L       I+++            LG+ +C           +    ++ +   +   
Sbjct: 102 YTNLDVPIQ--INDI----------LNLGKTNCLAKCKF---EKENITLKECMGYNQWTP 146

Query: 179 GDI 181
            +I
Sbjct: 147 KNI 149


>UniRef50_A5TU43 Putative uncharacterized protein n=3 Tax=Fusobacterium
          RepID=A5TU43_FUSNP
          Length = 366

 Score = 52.7 bits (125), Expect = 8e-06,   Method: Composition-based stats.
 Identities = 10/76 (13%), Positives = 20/76 (26%), Gaps = 2/76 (2%)

Query: 2  RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             L + L      + +      + T   P  S ++G L    G    D  S+    +  
Sbjct: 1  MEALRIILKQSSANYRKAGTVDNKMTYPLPIPSTIIGALHNICGY--TDYHSMDISIQGK 58

Query: 62 QFAVRCDELILDDRRV 77
            ++            
Sbjct: 59 FTSLSRRVYTDYCFLN 74


>UniRef50_C3WMW5 Putative uncharacterized protein n=1 Tax=Fusobacterium sp. 2_1_31
          RepID=C3WMW5_9FUSO
          Length = 340

 Score = 52.4 bits (124), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 11/67 (16%), Positives = 22/67 (32%), Gaps = 2/67 (2%)

Query: 2  RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             L + L      + +      + T   P  + ++G L    G +  +  S+    +  
Sbjct: 1  MEALRIVLKQSSANYRKAGTIDNKMTYPLPIPATVIGALHNICGYR--EYHSMDISIQGN 58

Query: 62 QFAVRCD 68
            AV  D
Sbjct: 59 FEAVSKD 65


>UniRef50_B1R9P4 Crispr-associated protein Cas5 n=5 Tax=Clostridiales
          RepID=B1R9P4_CLOPE
          Length = 364

 Score = 52.4 bits (124), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 6/46 (13%), Positives = 14/46 (30%)

Query: 2  RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQ 47
             L + L      + +      + T   P  S ++G +      +
Sbjct: 1  MKALRIILTQNSANYRREETTVNKMTYPLPPFSTVIGAIHNACNYK 46


>UniRef50_D0GJK9 CRISPR-associated Cas5 family protein n=1 Tax=Leptotrichia
           goodfellowii F0264 RepID=D0GJK9_9FUSO
          Length = 209

 Score = 52.0 bits (123), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 20/135 (14%), Positives = 44/135 (32%), Gaps = 6/135 (4%)

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQT---WREYLCDASFTVALW 121
           V       +   + ++   +Y + +            + I T   + E L D + T+ + 
Sbjct: 2   VHSLCDFKEYNPMEISVAGNYFSKVNDYYTKHEFNKSDNIITGPAYVELLVDVNLTIHII 61

Query: 122 LTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDI 181
               +   I ++  A  KP+    LGRR       +     + +  +K L   +     I
Sbjct: 62  PRDQSDESIQKILNAFEKPKEYLSLGRRE---DIVVINKVKEVAIEKKKLEKDKRYDKGI 118

Query: 182 YSEESVTGHHLKFTA 196
           ++   V     +   
Sbjct: 119 FAYIPVNFAVGRLVK 133


>UniRef50_Q74N42 NEQ020 n=1 Tax=Nanoarchaeum equitans RepID=Q74N42_NANEQ
          Length = 234

 Score = 52.0 bits (123), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 29/226 (12%), Positives = 68/226 (30%), Gaps = 33/226 (14%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDD-TSSLQALSES 60
              L  R++     +     +  + +      +  LGL+G   G  R +    L+ L   
Sbjct: 1   MKALAFRISFFEHLFKNHYTKAFKLSYPTLLPTEALGLIGNICGYDRKNVYKELKDLYFG 60

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL 120
             F             +    + + +      +   G K    I   + Y  ++   V +
Sbjct: 61  STF-------------LDGYYIEE-NITFIQFKKETGGKYRSGIVKSQVY-HNSEHLVII 105

Query: 121 WLTPH--ATMVISELEK-------------AVLKPRYTPYLGRRSCPLTHPLFLGTCQAS 165
                     ++++++               ++KP   PY G           L      
Sbjct: 106 AGDEKKLNEKILNKIKTLNSDPIENNLGKWLLVKPIRYPYGGWNDFFAKDIRILDKFLEV 165

Query: 166 DPQKALLNYEPVG--GDIYSEESVTGHHLKFTARDEPMITLPRQFA 209
           + ++ +  Y P+     I     +    +K+  + E  + + R +A
Sbjct: 166 EEKENVRGYVPLDWVKSINENSEIETMPVKYKNKMEYFVFIKRGYA 211


>UniRef50_Q1J1U3 CRISPR-associated protein, CT1134 n=3 Tax=Deinococci
           RepID=Q1J1U3_DEIGD
          Length = 251

 Score = 51.2 bits (121), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 30/232 (12%), Positives = 59/232 (25%), Gaps = 44/232 (18%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACL---------GIQRDDTSS 53
              +L + G    + +P  +  R +    T S    +  A              R + S 
Sbjct: 9   RTFVLEVWGDYGCFTRPELKVERMSYPVMTPSAARNIFDAIYLEFDPQTRRPAHRWEISR 68

Query: 54  LQALSESVQFAV-RCDELILDDRRVSVTGLRD----YHTVLGAREDYRGLKSHETIQTWR 108
           ++ L      A+ R +             ++D       +  A +D  G  +    Q   
Sbjct: 69  IEILEPVRYVALMRNEVKEKISEPSVKKWMKDPAQLVPILADATKDEVGTDTKGRTQRQT 128

Query: 109 EYLCDASFTV--ALWLTPHATMVISELEKAVLK------PRYTPYLGRRSCPLTHPLFLG 160
             L    + +     L      +  ++E++  +        + PYLG R       L   
Sbjct: 129 MALKSPHYRISGHAVLFEEDGALRQKIERSFERRARRGQCIFQPYLGCREFAAAFEL--- 185

Query: 161 TCQASDPQKALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASRE 212
                           V              + +   D        +  SR 
Sbjct: 186 ----------------VAEQPVVPPIPHDEEVGWMLYDV---FDLSRPGSRN 218


>UniRef50_B4VYG4 CRISPR-associated protein Cas5, Dvulg subtype n=1 Tax=Microcoleus
           chthonoplastes PCC 7420 RepID=B4VYG4_9CYAN
          Length = 257

 Score = 50.0 bits (118), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 23/157 (14%), Positives = 46/157 (29%), Gaps = 18/157 (11%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           +  ++ G    + +P F+  + T    T S   G+  +           +Q         
Sbjct: 56  ITFKIWGDRALFTRPEFKTEQVTYDVITPSAAKGIAESIFWKPEIQYQVIQ--------- 106

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL---- 120
           +   + I     +  T      +   A+         +  Q     L D ++ V +    
Sbjct: 107 ISLLKSIQKASILRNTLKSR-QSHRTAQSGGILEIESDRTQRHALILNDVAYLVTIQMQR 165

Query: 121 --WLTPHATMVISELEKAVLK--PRYTPYLGRRSCPL 153
               T   T  +   ++ + K      PYLG R    
Sbjct: 166 QSHATDPLTKYLEIFKRRLAKGQCFQQPYLGCREFVA 202


>UniRef50_C6AL37 Crispr-associated protein Cas5, dvulg subtype n=12
           Tax=Proteobacteria RepID=C6AL37_AGGAN
          Length = 224

 Score = 49.7 bits (117), Expect = 7e-05,   Method: Composition-based stats.
 Identities = 29/221 (13%), Positives = 55/221 (24%), Gaps = 42/221 (19%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
            + + L + G    + +P  +  R +    T S   G+L A            +     V
Sbjct: 1   MNQIRLHIWGDYACFIRPEMKVERVSYDVITPSAARGILAAV---------HWKPAIRWV 51

Query: 62  QFAVRCDELILDDRRVSVTGLRDYH-------TVLGAREDYRGLKSHETIQTWREYLCDA 114
              +   + I  +                       +  D   L   +  Q     L D 
Sbjct: 52  IDRIYVLKPIRFESVRRNELGGKISAGKVSGAMKRKSVADLYTLIEDDRQQRAATVLKDV 111

Query: 115 SFTVA----LWLTPHATMVISELEKAVLK------PRYTPYLGRRSCPLTHPLFLGTCQA 164
           ++ +     L     A   +++  +   +          P LG R  P            
Sbjct: 112 AYVIEAHAVLTAKAGADETVTKHIEMFKRRAKKGQCFQQPCLGVREFPADF--------- 162

Query: 165 SDPQKALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLP 205
                AL++           ES     L +   D  +    
Sbjct: 163 -----ALIDEGEPLPPSALSESEANRDLGWMLHD--IDFDH 196


>UniRef50_C8KYK7 CRISPR-associated RAMP Csd5d family protein n=4 Tax=Bacteria
           RepID=C8KYK7_9PAST
          Length = 214

 Score = 49.7 bits (117), Expect = 7e-05,   Method: Composition-based stats.
 Identities = 24/187 (12%), Positives = 50/187 (26%), Gaps = 24/187 (12%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
            IL ++G +  + +P  +  R +    T S    +L A L          +       F 
Sbjct: 3   FILEISGELACFTRPELKVERVSYPVITPSSARNILMAIL---------WKPAIRWRVFR 53

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTP 124
           +   + I                           +   ++      L D ++ +      
Sbjct: 54  IEILKPIQWVNVRRNEIGVKMSDRSQGLYIEDNRQQRASML-----LRDVAYRIHADFEM 108

Query: 125 HAT--------MVISELEKAVLKPRY--TPYLGRRSCPLTHPLFLGTCQASDPQKALLNY 174
                        +   ++   K +Y   PYLG R  P    L          +    ++
Sbjct: 109 TDEAGEGDNRTKFVEMFKRRASKGQYFHQPYLGCREFPCHFRLLEKAEDGLPREDITQDF 168

Query: 175 EPVGGDI 181
             +  D+
Sbjct: 169 GFMLYDM 175


>UniRef50_Q8F1E3 Fruiting body developmental protein S-like protein n=2
           Tax=Leptospira interrogans RepID=Q8F1E3_LEPIN
          Length = 207

 Score = 49.3 bits (116), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 27/185 (14%), Positives = 50/185 (27%), Gaps = 25/185 (13%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
              LIL    P+ ++        + +   P  S L+G+  +  G+  D        S  +
Sbjct: 1   MDPLILYYEIPIASFRPYQSREYQDSYPVPPPSTLIGMSLSLCGLSMD--HRKFFSSCEM 58

Query: 62  QFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALW 121
             AV             +  L D            G    +    ++E +      VA  
Sbjct: 59  CSAVADSNPARSTVLRRMRRLGD-----------SGRDPKQRRPEYQELVTGIRGIVAYR 107

Query: 122 LTPHATMVISELEKAVLKPRYT-----PYLGRRSCPLTHPLFLGTCQASDPQKALLNYEP 176
             P    +   ++  +  P          LG  S  +             P     N+  
Sbjct: 108 GLPAE--LAKPMKTVLTTPEKIIRYGGLSLGESSFLVDV-----IRLFELPDTTQSNWSW 160

Query: 177 VGGDI 181
           +  D+
Sbjct: 161 LIPDM 165


>UniRef50_Q2J7P3 Putative uncharacterized protein n=1 Tax=Frankia sp. CcI3
           RepID=Q2J7P3_FRASC
          Length = 221

 Score = 48.9 bits (115), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 29/213 (13%), Positives = 58/213 (27%), Gaps = 26/213 (12%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           + +++      + +P F   R +    T +  +G+L +         +           A
Sbjct: 15  VAVQVWAEGALFTRPEFRVERVSYPVMTPTAAVGVLESIFWKPEFRWAP---------VA 65

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV--ALWL 122
           +     +                   A    R        Q     L D ++ +   + L
Sbjct: 66  IEVLRPLHQFTLRRNETYDLPLLSDAASGVRRIDTVANRDQRSAVCLKDVAYRIHAHVEL 125

Query: 123 TPHATMVISELEKAVLK------PRYTPYLGRRSCPLTH------PLFLGTCQASDPQKA 170
             HAT  ++   +   +          PYLG R  P +       P++            
Sbjct: 126 QDHATKDVAAYREQFRRRVSRGACFQQPYLGAREFPASFAPPDGTPVWKQDEDLGVMLHR 185

Query: 171 LLNYEPVGGDIYSEESVTGHHLKF---TARDEP 200
           + +  PV  D ++     G           D P
Sbjct: 186 IHHGPPVAFDWFTARLDAGVLYVPRAGIRGDVP 218


>UniRef50_UPI0001BC6553 hypothetical protein FgonA2_03326 n=3 Tax=Fusobacterium
          RepID=UPI0001BC6553
          Length = 369

 Score = 48.9 bits (115), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 7/76 (9%), Positives = 19/76 (25%), Gaps = 2/76 (2%)

Query: 2  RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESV 61
             L + L      + +      + T   P  S ++G L      +  +   +    +  
Sbjct: 1  MKALRIVLRQTSANYRKTGCLENKMTYPLPLPSTIIGALHNICDYK--EYHPMDVSIQGK 58

Query: 62 QFAVRCDELILDDRRV 77
            ++            
Sbjct: 59 FSSLSKRAYTDYCFLN 74


>UniRef50_Q72WF9 CRISPR-associated protein, CT1134 family n=19 Tax=Bacteria
           RepID=Q72WF9_DESVH
          Length = 227

 Score = 48.5 bits (114), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 35/202 (17%), Positives = 61/202 (30%), Gaps = 8/202 (3%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQ--RDDTSSLQALSESVQ 62
           + LR+ G    + +P  +  R +      S   G+L A       R     +  L   V 
Sbjct: 11  IRLRVWGDYACFTRPEMKVERVSYDVMPPSAARGILEAIHWKPAIRWIVDRIHVLRPIVF 70

Query: 63  FAV-RCDELILDDRRVSVTGLRDYHTVL-GAREDYRGLKSHETIQTWREYLCDASFTVAL 120
             V R +      +    T +RD   +     +     +   T+    +Y+ +A F +  
Sbjct: 71  DNVRRNEVSSKIPKPNPATAMRDRKPLYFLVDDGSNRQQRAATLLRNVDYVIEAHFELTD 130

Query: 121 WLTPHAT--MVISELEKAVL--KPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEP 176
                      +    +     +    P LG R  P +  L  G    S       +   
Sbjct: 131 KAGAEDNAGKHLDIFRRRARAGQSFQQPCLGCREFPASFELLEGDVPLSCYAGEKRDLGY 190

Query: 177 VGGDIYSEESVTGHHLKFTARD 198
           +  DI  E  +T    K    D
Sbjct: 191 MLLDIDFERDMTPLFFKAVMED 212


>UniRef50_A5D0R8 Putative uncharacterized protein n=3 Tax=Bacteria
           RepID=A5D0R8_PELTS
          Length = 238

 Score = 48.5 bits (114), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 22/157 (14%), Positives = 45/157 (28%), Gaps = 23/157 (14%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           + +++ G    + +P F+  R +    T S   G+L A                      
Sbjct: 7   VKVKVWGEYACFTRPEFKVERVSYPVITPSAARGVLEAIFWKPEFRWE------------ 54

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVAL---- 120
                 I     V    +             + +   +  Q    ++ + S+ +      
Sbjct: 55  ---VREIWVLNEVREEVIVRNEIESRQSPRAKCIIEEQHQQRATLFIKNPSYLLFADIAL 111

Query: 121 --WLTPHATMVISELEKAVL--KPRYTPYLGRRSCPL 153
             ++       I +  + V   K  + PYLG R C  
Sbjct: 112 KEFVDSPKKKYIEQFNRRVEKGKCFHQPYLGTRECTA 148


>UniRef50_A9GDF4 Fruiting body developmental protein S n=2 Tax=Bacteria
           RepID=A9GDF4_SORC5
          Length = 224

 Score = 47.7 bits (112), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 15/122 (12%), Positives = 35/122 (28%), Gaps = 13/122 (10%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
            + +R+  P  ++ +        +  F   + + G+L + +G +          S +   
Sbjct: 1   MITVRVQAPYASFRRSYARSFAESYPFAPPATVYGMLLSLVGER----------SRARHV 50

Query: 64  AVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLT 123
            VR          V+ T  +               +       + E LC   F   +  +
Sbjct: 51  GVRLAFAYARQPAVATTLRK---LSRYKYGVATKQEKLGNAPDFVETLCGLDFLCWIDSS 107

Query: 124 PH 125
             
Sbjct: 108 GE 109


>UniRef50_C0D371 Putative uncharacterized protein n=1 Tax=Clostridium asparagiforme
           DSM 15981 RepID=C0D371_9CLOT
          Length = 200

 Score = 47.7 bits (112), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 29/205 (14%), Positives = 62/205 (30%), Gaps = 15/205 (7%)

Query: 7   LRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAV- 65
             +AGP  ++ +P    +  +   PTRS ++G++  C+   R+     + +         
Sbjct: 10  FEVAGPAASYARPDAGSSPISSAVPTRSAIIGMM-TCVAFSREAYFWPERIELCAHPMYH 68

Query: 66  RCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPH 125
           R  +      R S    +   TVL   +                 L +        +   
Sbjct: 69  RYTQNYNGPLRKSQAPFQIMATVLINVDYKIYGTVKGYAPPTA--LHNP-------MHQL 119

Query: 126 ATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDIYSEE 185
             + +  L+  +     TP LG      ++  F      +   + +    P   D   + 
Sbjct: 120 RDVFMRRLKSGL--FYRTPSLGLSEFIPSY--FGPLRDDTQVDRTINLEIPSLLDTMFDR 175

Query: 186 SVTGHHLKFTARDEPMITLPRQFAS 210
              G       ++  ++     FA 
Sbjct: 176 PTDGQLSPTFMQNVKIVEGVLHFAE 200


>UniRef50_B8FSK6 CRISPR-associated protein Cas5 n=3 Tax=Clostridiales
           RepID=B8FSK6_DESHD
          Length = 224

 Score = 46.6 bits (109), Expect = 7e-04,   Method: Composition-based stats.
 Identities = 25/235 (10%), Positives = 54/235 (22%), Gaps = 40/235 (17%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           + + +AG    W +P       +   PT S +  +  +          +     E +   
Sbjct: 8   IAMEIAGNTAMWTRPDSGDCPVSYPAPTYSAVKAIFESV---------AWGPGVEIIPTK 58

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTP 124
           V     I      +           G     + +K     Q +   L D  + +   + P
Sbjct: 59  VELCAPIQYHSYCTNY--------GGPLRSTKSIKEGNNYQLYATVLIDVCYRLYAEVVP 110

Query: 125 HATM--------------------VISELEKAVLK--PRYTPYLGRRSCPLTHPLFLGTC 162
           +                         S   + + +      P LG +    ++       
Sbjct: 111 YKDKSRLPESAVQWDKKTTSPGHAYQSIFNRRLKRGQCYSIPTLGWKEFTPSY-FGEFRD 169

Query: 163 QASDPQKALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIK 217
                  AL    P        +            D  +     ++  R     +
Sbjct: 170 TTQVLSDALPIVIPSMLRRVFAKGYGSPVSYVYDNDLVIRNGVLEYPQRSENYAQ 224


>UniRef50_C5EH15 Crispr-protein cas5 family n=1 Tax=Clostridiales bacterium
           1_7_47FAA RepID=C5EH15_9FIRM
          Length = 242

 Score = 46.2 bits (108), Expect = 8e-04,   Method: Composition-based stats.
 Identities = 29/237 (12%), Positives = 63/237 (26%), Gaps = 35/237 (14%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M     + + G    + +P  +  R +   PT   + G+L +            +     
Sbjct: 1   MSYGFKIMVTGDYACFTRPELKVERVSYDVPTPGAMEGMLKSIY---------WKPAIRY 51

Query: 61  VQFAVRCDELILDDRRVSVTGLRD--YHTVLGAREDYRGLKSHETIQTWRE----YLCDA 114
           V   +   + I               Y  V        G     T ++  +     L + 
Sbjct: 52  VIDKIIVFQPIDFINIRRNEVKDKVLYSAVKSQMNGTGGNPCIYTSESRSQRAAMILKNV 111

Query: 115 SFTVALWLT----------PHATMVISELEKAVLKP--RYTPYLGRRSCPLTHPLFLGTC 162
            + V                  +   + +++ + +     TP LG    P+     +   
Sbjct: 112 MYGVEFHFELTGLKNDKETDTESKHFNIIKRRLERGQHYRTPCLGCSEFPVRDIRLVEDF 171

Query: 163 QASDPQKALLNYEPVGGDI--YSEESVTGHHLKFTARDEPMITLPRQFASREWYVIK 217
             +    ++L  E V      Y  +   G        D P      +F+ +   +  
Sbjct: 172 DLNLISSSILTQEDVDLGFMSYRVQFQDGGVPTNGDWDNP------KFSDKAVTIYY 222


>UniRef50_Q1H3R5 CRISPR-associated protein, CT1134 n=14 Tax=Bacteria
           RepID=Q1H3R5_METFK
          Length = 225

 Score = 45.8 bits (107), Expect = 0.001,   Method: Composition-based stats.
 Identities = 24/214 (11%), Positives = 49/214 (22%), Gaps = 26/214 (12%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M   + L + G    + +P  +  R +    T S   G+L A            +     
Sbjct: 1   MAYGVRLHVWGDYACFTRPEMKVERVSYDVMTPSAARGILTAI---------HWKPAIRW 51

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWRE-------YLCD 113
           V  ++   + I  +                +    RG           +        L D
Sbjct: 52  VVDSIHVLKPIRFESIRRNEVGSKASASKASGGMARGSVEGIYTLIEEDRQQRASTVLRD 111

Query: 114 ASFTV-------ALWLTPHAT-MVISELEKAVLK--PRYTPYLGRRSCPLTHPLFLGTCQ 163
            ++ +        L          +    +   +    + P +G R  P    L      
Sbjct: 112 VAYVIEAHFELTELAGEGDNPGKHLDIFNRRARRGQCHHQPCMGVREFPAFFSLIEPEMA 171

Query: 164 ASDPQKALLNYEPVGGDIYSEESVTGHHLKFTAR 197
                 +        G +  +            R
Sbjct: 172 LPASILSDEQKSRDLGWMLHDIDFDHGATPRFFR 205


>UniRef50_Q3SR91 CRISPR-associated protein, Csd5d family n=17 Tax=Bacteria
           RepID=Q3SR91_NITWN
          Length = 230

 Score = 45.4 bits (106), Expect = 0.001,   Method: Composition-based stats.
 Identities = 22/174 (12%), Positives = 41/174 (23%), Gaps = 26/174 (14%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSES 60
           M   + L++ G    + +P  +  R +    T S   G+L A            +     
Sbjct: 1   MTYGIRLKVWGDYACFTRPEMKVERVSYDVITPSAARGILEAI---------HWKPAIRW 51

Query: 61  VQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSH-------ETIQTWREYLCD 113
           V  A+   E                          RG              Q     L  
Sbjct: 52  VIDAIHVLERPRFQSIRRNEVGSKAPAGKIKSAMKRGDLEGLQLLVDEGRQQRASTVLVK 111

Query: 114 ASFTVALWLT--------PHATMVISELEKAVLK--PRYTPYLGRRSCPLTHPL 157
            ++ +              +    +    +   +    + P LG R    +  L
Sbjct: 112 PAYVIVARFELTGRGEEGDNEGKHLDIFNRRARRGQCFHQPCLGTREFAASFTL 165


>UniRef50_C1F2B9 CRISPR-associated protein Cas5, Dvulg subtype n=1
           Tax=Acidobacterium capsulatum ATCC 51196
           RepID=C1F2B9_ACIC5
          Length = 241

 Score = 45.0 bits (105), Expect = 0.002,   Method: Composition-based stats.
 Identities = 20/175 (11%), Positives = 45/175 (25%), Gaps = 18/175 (10%)

Query: 1   MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDT-------SS 53
           M   + L ++G    +  P  +  R +   PT S    +L A L                
Sbjct: 1   MSLAVRLHVSGDFACFTSPASKVERYSYPLPTPSAARNILDAILWKPEFRWIVTRIMLVR 60

Query: 54  LQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRG-LKSHETIQTWREYLC 112
               +  +   +      +       T  +        +    G  +  +        L 
Sbjct: 61  HPRGTAGLPATIPLKRNEVQSTIAPGTVRQWMREPAAYQPLAAGAGQGTDGTPRMTTGLK 120

Query: 113 DASFTV----ALWLTPHATMVISELEKAVLK------PRYTPYLGRRSCPLTHPL 157
           + ++ +     ++ +        +  +   +          PYLG R       L
Sbjct: 121 NVAYVIEAYPHVFDSNGGENTPKKYVEMFERRAAKGQCFSRPYLGCREFAADFRL 175


>UniRef50_C4DD59 CRISPR-associated protein Cas5, Dvulg subtype n=1
           Tax=Stackebrandtia nassauensis DSM 44728
           RepID=C4DD59_9ACTO
          Length = 231

 Score = 43.5 bits (101), Expect = 0.006,   Method: Composition-based stats.
 Identities = 25/157 (15%), Positives = 45/157 (28%), Gaps = 17/157 (10%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           + +++ G    + +P  +  R T    T S   G+L A                     A
Sbjct: 20  VAVQVWGDAALFTRPELKAERLTYPVMTPSAAKGVLEAIYWKPEMAYQ---------VVA 70

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV--ALWL 122
           +   + I                   A+   R   + +  Q     L D ++ +   + L
Sbjct: 71  IEVLKPIKQFTVRRNETNDVASLRDAAKGVRRIDTAAKRDQRNAVCLRDVAYRIHAHIRL 130

Query: 123 TPHATMVISELEKAVLK-----PRY-TPYLGRRSCPL 153
            PHA   +        +       +  PYLG R    
Sbjct: 131 QPHANKPVVAYRDQFRRRVDKGACFAQPYLGTREFTA 167


>UniRef50_A3J8H9 CRISPR-associated protein, CT1134 family n=2 Tax=Bacteria
           RepID=A3J8H9_9ALTE
          Length = 220

 Score = 43.1 bits (100), Expect = 0.007,   Method: Composition-based stats.
 Identities = 21/194 (10%), Positives = 44/194 (22%), Gaps = 31/194 (15%)

Query: 7   LRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVR 66
           L ++G    + +P  +  R +    T S    +  A L          +   +     + 
Sbjct: 5   LEISGEFACFTRPEMKVERVSYDVITPSAARAIFEAIL---------WKPAIQWHITRIE 55

Query: 67  CDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWRE---------YLCDASFT 117
               I                +               +  + +          L D  + 
Sbjct: 56  VLNPIKWMNLRRNEVES---IISARTAQTAMKNGSGHLGIYVDEERQQRASLLLKDVRYR 112

Query: 118 VA----LWLTPHATMVISELEKAVLK------PRYTPYLGRRSCPLTHPLFLGTCQASDP 167
           +     +          ++      +          PYLG R       L  G     DP
Sbjct: 113 LHGEFTMTEKAGPQDSAAKFADMFRRRAEKGQCFNQPYLGCREFTCDFALVDGDTANPDP 172

Query: 168 QKALLNYEPVGGDI 181
                +   +  D+
Sbjct: 173 INDTRDLGFMLYDL 186


>UniRef50_Q07766 Fruiting body developmental protein S n=1 Tax=Myxococcus xanthus DK
           1622 RepID=DEVS_MYXXD
          Length = 214

 Score = 42.7 bits (99), Expect = 0.009,   Method: Composition-based stats.
 Identities = 17/140 (12%), Positives = 37/140 (26%), Gaps = 16/140 (11%)

Query: 4   YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQF 63
            + L L+ P+  W +        T   P  +   G L + +G         +      + 
Sbjct: 1   MIALELSVPVACWRKGRARELVETEVLPPPATCYGALLSLVG------EQDRERHRGCRV 54

Query: 64  AVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLT 123
                   +       T LR +      +               ++ + DA   V     
Sbjct: 55  TAGVLNAPVIS-----TVLRTFWRSKNLKVAK--GNDENAAPDQQQLVIDARLVVWCDSR 107

Query: 124 PHA---TMVISELEKAVLKP 140
                   +   + +A+ +P
Sbjct: 108 EEPDSGESLEDRVVRAMREP 127


>UniRef50_Q8TYH7 Coenzyme F420-reducing hydrogenase, beta subunit n=1
           Tax=Methanopyrus kandleri RepID=Q8TYH7_METKA
          Length = 377

 Score = 42.3 bits (98), Expect = 0.012,   Method: Composition-based stats.
 Identities = 28/180 (15%), Positives = 54/180 (30%), Gaps = 25/180 (13%)

Query: 59  ESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQT---------WRE 109
           E ++ A+R D + +           D   ++          S+    T          RE
Sbjct: 33  ELLRHALREDLVDVVVCVERGADALDGRPIVVDDPAEVPSGSYHCAPTQLARLVAELHRE 92

Query: 110 YLCDASFTVALWLTPHATMVISELEKA-VLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQ 168
              D +  VA+   P     +  L +  ++ P     +G            GT +     
Sbjct: 93  ---DPTLRVAVTCRPCDARTLDRLAERDLVNPDRVYRIGLNC--------GGTFEPRVVL 141

Query: 169 KALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITL----PRQFASREWYVIKGGMDVSQ 224
           + L  +     D+  EE V GH +      E +         Q + R     +   ++ +
Sbjct: 142 EILEEHGVDPLDVEREEVVKGHLVIELRDGEEISVSIDELEEQDSGRRENCRRCDENIPE 201


>UniRef50_Q57827 Uncharacterized protein MJ0382 n=1 Tax=Methanocaldococcus
           jannaschii RepID=Y382_METJA
          Length = 245

 Score = 42.3 bits (98), Expect = 0.013,   Method: Composition-based stats.
 Identities = 30/183 (16%), Positives = 66/183 (36%), Gaps = 12/183 (6%)

Query: 2   RSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGA---CLGIQRDDTSSLQALS 58
              L+  L  P  ++G+ +    R +   P+ S L G L      LG ++    SL  ++
Sbjct: 3   MEALVALLRFPFYSFGKQS-YQVRQSLLLPSPSALKGALAKGIILLGGKKG--KSLDEIA 59

Query: 59  ESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV 118
           +     +    + +  +    + ++    +   R         ++    REY+  A   +
Sbjct: 60  KKTVEELENKLIYVGAKPYKSSIIKTPILLKRLRNLEDQKNPEKSDAMRREYVF-AREIL 118

Query: 119 ALWLTPHATMVISELEKAVLKPRYTP-YLGRRSCPLTHP--LFLGTCQASDPQKALLNYE 175
           A+++      +  E +  +LK  Y    LG   C        ++   +   P K  + ++
Sbjct: 119 AIYVFR--RKLSEEEKDLMLKAVYLIDQLGDTECVGNVIKTEWVEVKEEKAPLKTYVKFK 176

Query: 176 PVG 178
            V 
Sbjct: 177 KVS 179


>UniRef50_Q2RL62 CRISPR-associated protein, CT1134 n=1 Tax=Moorella thermoacetica
           ATCC 39073 RepID=Q2RL62_MOOTA
          Length = 233

 Score = 41.6 bits (96), Expect = 0.019,   Method: Composition-based stats.
 Identities = 26/216 (12%), Positives = 53/216 (24%), Gaps = 33/216 (15%)

Query: 5   LILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFA 64
           L +++ G +  + +P  +  R +    T S   G+L A            +         
Sbjct: 19  LAVKVWGDLACFTRPEMKVERVSYPVMTPSAARGILEAIFWKP---EFRWRVRQ------ 69

Query: 65  VRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWRE-----YLCDASFTV- 118
           +   + I     +                   G   +      R       L + ++ + 
Sbjct: 70  IEVLKPIRYFSILRNEVNDKMVVSTARGWARNGGGYYADQPQHRAQRHTLALREVAYIIR 129

Query: 119 ------ALWLTPHATMVISELEKAVLK--PRYTPYLGRRSCPLTHPLFLGTCQASDPQKA 170
                 A     H      +  + V +    + PYLG R               S P   
Sbjct: 130 AEQVMAAHARDIHPAKYRDQFRRRVERGQCYHRPYLGCREFCA-------FFGPSSPADQ 182

Query: 171 LLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPR 206
            + +    G +  +               P+    R
Sbjct: 183 PIKHSEYLGQMLLDLKYNSDGSGEGR---PVFFNAR 215


>UniRef50_Q1CWU1 CRISPR-associated protein Cas5, Dvulg subtype n=1 Tax=Myxococcus
           xanthus DK 1622 RepID=Q1CWU1_MYXXD
          Length = 221

 Score = 40.8 bits (94), Expect = 0.032,   Method: Composition-based stats.
 Identities = 20/170 (11%), Positives = 40/170 (23%), Gaps = 25/170 (14%)

Query: 3   SYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQ 62
               +R  GP+  + +P  +  R +    T S   G+L A L          +       
Sbjct: 9   RSFRVRARGPVACFTRPEMKAERVSYEVMTPSAARGVLEAILWKPAIRWHVHE------- 61

Query: 63  FAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTV---- 118
             +     +                       +      +  Q     L D  + +    
Sbjct: 62  --IAVLAPVRWTSFRRNEV-----NSRATVGKFDYAADEDRAQRNTVALRDVDYVITASF 114

Query: 119 ----ALWLTPHATMVISE-LEKAVLKPRYT--PYLGRRSCPLTHPLFLGT 161
                            +  E+ + + ++   PYLG R            
Sbjct: 115 ALVPGKAGPDDNVRKFEDMFERRLERGQFFHAPYLGCREFAARVEPAEDV 164


>UniRef50_B8IGC7 CRISPR-associated protein Cas5 n=1 Tax=Methylobacterium nodulans
           ORS 2060 RepID=B8IGC7_METNO
          Length = 211

 Score = 40.8 bits (94), Expect = 0.032,   Method: Composition-based stats.
 Identities = 31/214 (14%), Positives = 64/214 (29%), Gaps = 20/214 (9%)

Query: 7   LRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVR 66
           L +AGP+  + +P   GT  +   PT S    +  +   ++  D        E  +    
Sbjct: 8   LEVAGPLAMFARPDAGGTPTSYPAPTCSAAKSIFESIAMLRSGDAWIRPKRVEICKKKGE 67

Query: 67  CDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPH- 125
               I   R  +           G       +     +Q +   L D  F +   +    
Sbjct: 68  SGGSIRYQRYTTNY--------GGPLRKADLVGKRAGMQLFATVLADVCFRLYGEIDGKP 119

Query: 126 ------ATMVISELEK---AVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEP 176
                     + +L     A  +   TP LG R    T   +       +  + + ++ P
Sbjct: 120 ARAGVNPRHHLQDLFNRRIARGQCFRTPSLGWREF--TCSYWGPFRPEYEVDEDIEDFIP 177

Query: 177 VGGDIYSEESVTGHHLKFTARDEPMITLPRQFAS 210
                  ++   G +    A++  ++     +A 
Sbjct: 178 SMLLKTWDKPRDGAYEPIFAQNVSIVRGVLDYAE 211


>UniRef50_B7A743 Putative uncharacterized protein n=1 Tax=Thermus aquaticus Y51MC23
           RepID=B7A743_THEAQ
          Length = 169

 Score = 39.6 bits (91), Expect = 0.071,   Method: Composition-based stats.
 Identities = 15/111 (13%), Positives = 32/111 (28%), Gaps = 20/111 (18%)

Query: 114 ASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDP--QKAL 171
            ++ V +        ++ +L +A+  P Y   LG    P      LG  +A      + +
Sbjct: 38  VAYEVYVA--SRDAGLMGDLARALEAPAYPLSLG----PA---FALGWAEAVTLARGEVV 88

Query: 172 LNYE------PVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVI 216
             +E           +  +E +    L        +         R    +
Sbjct: 89  EGWEGKGIGWWQADRLRLKELLPEVRLYRDRFPVALSPDRN---PRRVEEL 136


  Database: uniref50.fasta
    Posted date:  Mar 8, 2010 10:38 AM
  Number of letters in database: 1,040,396,356
  Number of sequences in database:  3,077,464
  
Lambda     K      H
   0.313    0.136    0.362 

Lambda     K      H
   0.267   0.0415    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,307,267,282
Number of Sequences: 3077464
Number of extensions: 55110769
Number of successful extensions: 170922
Number of sequences better than 1.0e-01: 225
Number of HSP's better than  0.1 without gapping: 430
Number of HSP's successfully gapped in prelim test: 110
Number of HSP's that attempted gapping in prelim test: 169299
Number of HSP's gapped (non-prelim): 584
length of query: 224
length of database: 1,040,396,356
effective HSP length: 124
effective length of query: 100
effective length of database: 658,790,820
effective search space: 65879082000
effective search space used: 65879082000
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.4 bits)
S2: 91 (39.6 bits)
