BLASTP 2.2.22 [Sep-27-2009]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= batch____
         (277 letters)

Database: uniref50.fasta 
           3,077,464 sequences; 1,040,396,356 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P24200 5-methylcytosine-specific restriction enzyme A n...   574   e-162
UniRef50_A9BU78 HNH endonuclease n=4 Tax=Burkholderiales RepID=A...   131   2e-29
UniRef50_C3K0B7 Putative 5-methylcytosine-specific restriction e...   128   2e-28
UniRef50_Q2Y8M1 HNH nuclease n=1 Tax=Nitrosospira multiformis AT...   122   2e-26
UniRef50_A0KIQ7 Probable 5-methylcytosine-specific restriction e...   120   4e-26
UniRef50_A6QD09 5-methylcytosine-specific restriction enzyme A n...   115   2e-24
UniRef50_Q1YK78 Putative 5-methylcytosine-specific restriction e...   114   3e-24
UniRef50_UPI00016A2859 HNH endonuclease n=1 Tax=Burkholderia tha...   110   7e-23
UniRef50_Q3K870 Putative 5-methylcytosine-specific restriction e...   104   4e-21
UniRef50_C3FAM5 HNH nuclease n=4 Tax=Bacillus cereus group RepID...   100   4e-20
UniRef50_D0KA86 HNH endonuclease n=2 Tax=Enterobacteriaceae RepI...   100   8e-20
UniRef50_D2C2V7 HNH endonuclease n=1 Tax=Dickeya dadantii Ech586...    98   3e-19
UniRef50_Q312Y0 HNH nuclease n=1 Tax=Desulfovibrio desulfuricans...    97   4e-19
UniRef50_D0Z3H8 HNH nuclease n=1 Tax=Photobacterium damselae sub...    97   6e-19
UniRef50_A2SMM5 Putative uncharacterized protein n=1 Tax=Methyli...    94   4e-18
UniRef50_C9PPM2 5-methylcytosine-specific restriction enzyme A n...    93   1e-17
UniRef50_A8ZWC1 HNH endonuclease n=1 Tax=Desulfococcus oleovoran...    91   4e-17
UniRef50_A6VSV6 HNH endonuclease n=1 Tax=Marinomonas sp. MWYL1 R...    91   5e-17
UniRef50_A4SC99 HNH endonuclease n=1 Tax=Chlorobium phaeovibrioi...    91   5e-17
UniRef50_C4SUH5 Restriction endonuclease n=1 Tax=Yersinia freder...    90   7e-17
UniRef50_B5EI94 HNH endonuclease n=1 Tax=Geobacter bemidjiensis ...    90   1e-16
UniRef50_C7HJ98 HNH endonuclease n=1 Tax=Clostridium thermocellu...    89   2e-16
UniRef50_C6ANH6 HNH nuclease n=1 Tax=Aggregatibacter aphrophilus...    89   2e-16
UniRef50_A3JQK6 HNH nuclease n=1 Tax=Rhodobacterales bacterium H...    87   5e-16
UniRef50_C2KXT9 Putative uncharacterized protein n=1 Tax=Oribact...    86   2e-15
UniRef50_B4S2Y7 HNH nuclease n=2 Tax=Proteobacteria RepID=B4S2Y7...    86   2e-15
UniRef50_Q1QEV2 HNH endonuclease n=5 Tax=Gammaproteobacteria Rep...    86   2e-15
UniRef50_C0WRI9 Possible HNH endonuclease n=1 Tax=Lactobacillus ...    84   4e-15
UniRef50_C0N619 HNH endonuclease domain protein n=1 Tax=Methylop...    82   2e-14
UniRef50_C3C627 Restriction endonuclease n=7 Tax=Bacillus RepID=...    82   3e-14
UniRef50_Q080H4 HNH endonuclease n=1 Tax=Shewanella frigidimarin...    80   8e-14
UniRef50_D2S1X8 HNH endonuclease n=1 Tax=Haloterrigena turkmenic...    79   1e-13
UniRef50_C9BZK6 Restriction endonuclease (Fragment) n=4 Tax=Firm...    79   2e-13
UniRef50_Q0BZ66 Conserved domain protein n=1 Tax=Hyphomonas nept...    79   2e-13
UniRef50_C4WNE8 Putative uncharacterized protein n=1 Tax=Ochroba...    78   4e-13
UniRef50_A9F818 Putative restriction endonuclease n=1 Tax=Phaeob...    72   3e-11
UniRef50_B1ZMM6 HNH endonuclease n=1 Tax=Opitutus terrae PB90-1 ...    69   1e-10
UniRef50_Q1L9I8 HNH nuclease n=2 Tax=cellular organisms RepID=Q1...    65   3e-09
UniRef50_A8R8M0 Putative uncharacterized protein n=1 Tax=Eubacte...    65   3e-09
UniRef50_Q3K789 Putative HNH endonuclease n=1 Tax=Pseudomonas fl...    65   3e-09
UniRef50_Q9L0M9 Putative uncharacterized protein SCO4631 n=3 Tax...    64   5e-09
UniRef50_B0N4T9 Putative uncharacterized protein n=1 Tax=Clostri...    64   8e-09
UniRef50_Q0KFQ5 Predicted restriction endonuclease n=1 Tax=Ralst...    60   6e-08
UniRef50_A3US95 Putative restriction endonuclease n=1 Tax=Vibrio...    60   8e-08
UniRef50_D1NJY2 Transcriptional regulator, XRE family n=1 Tax=Cl...    59   2e-07
UniRef50_D1BJK4 HNH endonuclease n=1 Tax=Sanguibacter keddieii D...    58   3e-07
UniRef50_A3U4A6 E14 prophage-like protein n=1 Tax=Oceanicola bat...    58   3e-07
UniRef50_A0YK66 Putative uncharacterized protein n=1 Tax=Lyngbya...    58   4e-07
UniRef50_C6LDW0 Product McrA n=1 Tax=Bryantella formatexigens DS...    56   1e-06
UniRef50_C0ZFI2 Putative uncharacterized protein n=1 Tax=Breviba...    55   2e-06
UniRef50_A3WFM1 5-methylcytosine-specific restriction enzyme A n...    55   3e-06
UniRef50_Q81E47 5-methylcytosine-specific restriction enzyme A n...    55   3e-06
UniRef50_Q723Z7 Conserved domain protein n=4 Tax=Listeria monocy...    55   3e-06
UniRef50_C4L074 HNH endonuclease n=1 Tax=Exiguobacterium sp. AT1...    55   4e-06
UniRef50_B5G9G0 HNH endonuclease n=1 Tax=Streptomyces sp. SPB74 ...    54   7e-06
UniRef50_B8KVR3 HNH endonuclease domain protein n=1 Tax=gamma pr...    53   1e-05
UniRef50_B3CDE4 Putative uncharacterized protein n=1 Tax=Bactero...    52   2e-05
UniRef50_B1ZSH9 Restriction endonuclease-like protein n=1 Tax=Op...    52   3e-05
UniRef50_C9XQW3 Putative uncharacterized protein n=2 Tax=Clostri...    51   4e-05
UniRef50_B0ACA5 Putative uncharacterized protein n=1 Tax=Clostri...    51   5e-05
UniRef50_Q39IU3 Putative uncharacterized protein n=1 Tax=Burkhol...    51   5e-05
UniRef50_C3GU40 HNH endonuclease n=2 Tax=Bacillus thuringiensis ...    51   6e-05
UniRef50_Q3EYN0 HNH endonuclease family protein n=1 Tax=Bacillus...    50   6e-05
UniRef50_Q6MJA3 Putative membrane protein n=1 Tax=Bdellovibrio b...    50   7e-05
UniRef50_B3EB35 HNH endonuclease n=1 Tax=Geobacter lovleyi SZ Re...    50   9e-05
UniRef50_C0QGN0 Putative 5-methylcytosine-specific restriction e...    50   1e-04
UniRef50_A6TVA6 HNH endonuclease n=6 Tax=Bacteria RepID=A6TVA6_A...    49   1e-04
UniRef50_Q64YP3 Putative uncharacterized protein n=1 Tax=Bactero...    49   2e-04
UniRef50_UPI0001A457FB putative 5-methylcytosine-specific restri...    49   2e-04
UniRef50_Q3IBU7 Putative HNH endonuclease n=1 Tax=Pseudoalteromo...    49   2e-04
UniRef50_Q65MN2 McrA n=2 Tax=Bacillus subtilis group RepID=Q65MN...    48   3e-04
UniRef50_C8U495 Endonuclease-like protein n=2 Tax=Escherichia co...    48   4e-04
UniRef50_C7V3C1 Predicted protein n=1 Tax=Enterococcus faecalis ...    47   5e-04
UniRef50_Q5YRW6 Putative endonuclease n=1 Tax=Nocardia farcinica...    47   7e-04
UniRef50_C6MKA5 HNH endonuclease n=1 Tax=Geobacter sp. M18 RepID...    47   7e-04
UniRef50_A0ZAT3 Putative uncharacterized protein n=1 Tax=Nodular...    47   7e-04
UniRef50_C9RBS6 HNH endonuclease n=4 Tax=Ammonifex degensii KC4 ...    47   8e-04
UniRef50_Q0HF94 Putative uncharacterized protein n=1 Tax=Shewane...    47   9e-04
UniRef50_Q538B5 MnlI restriction endonuclease n=2 Tax=Moraxella ...    47   9e-04
UniRef50_C2ECC9 Recombinase n=1 Tax=Lactobacillus ruminis ATCC 2...    46   0.001
UniRef50_Q46AN8 Putative uncharacterized protein n=1 Tax=Methano...    46   0.001
UniRef50_A0L1U4 HNH endonuclease n=1 Tax=Shewanella sp. ANA-3 Re...    46   0.001
UniRef50_C3AFV2 Putative uncharacterized protein n=1 Tax=Bacillu...    46   0.001
UniRef50_C4L1L5 HNH endonuclease n=2 Tax=Bacillales RepID=C4L1L5...    46   0.001
UniRef50_Q8DK67 Reverse transcriptase n=1 Tax=Thermosynechococcu...    46   0.001
UniRef50_A3YQ82 MnlI restriction endonuclease n=1 Tax=Campylobac...    46   0.001
UniRef50_Q8TKB6 Hnh endonuclease n=2 Tax=Methanosarcina RepID=Q8...    46   0.001
UniRef50_C3RB64 Predicted protein n=1 Tax=Bacteroides dorei 5_1_...    46   0.002
UniRef50_D0IIJ2 HNH endonuclease n=1 Tax=Vibrio sp. RC586 RepID=...    45   0.002
UniRef50_C6WXV3 HNH endonuclease n=3 Tax=Proteobacteria RepID=C6...    45   0.002
UniRef50_D2QLF4 HNH endonuclease n=1 Tax=Spirosoma linguale DSM ...    45   0.002
UniRef50_Q6EME6 Hnh endonuclease n=6 Tax=Enterobacteriaceae RepI...    45   0.003
UniRef50_A5V9C7 HNH endonuclease n=1 Tax=Sphingomonas wittichii ...    45   0.003
UniRef50_D2S2Y4 HNH endonuclease n=1 Tax=Haloterrigena turkmenic...    45   0.003
UniRef50_C3BJL8 Paclitaxel/taxanoid biosynthesis susceptibility ...    45   0.003
UniRef50_C4UQ38 Putative uncharacterized protein n=1 Tax=Yersini...    45   0.003
UniRef50_D2RK49 HNH endonuclease n=11 Tax=Bacteria RepID=D2RK49_...    45   0.003
UniRef50_B7JSJ9 DNA helicase, putative n=1 Tax=Bacillus cereus A...    45   0.004
UniRef50_D2AT16 Putative uncharacterized protein n=1 Tax=Strepto...    45   0.004
UniRef50_C3G8U4 HNH endonuclease n=1 Tax=Bacillus thuringiensis ...    45   0.004
UniRef50_D2YH85 Putative uncharacterized protein n=1 Tax=Vibrio ...    45   0.004
UniRef50_B3Z1Y7 Gp45 n=1 Tax=Bacillus cereus W RepID=B3Z1Y7_BACCE      44   0.004
UniRef50_C2LK08 Putative uncharacterized protein n=1 Tax=Proteus...    44   0.005
UniRef50_A9GYN9 Putative uncharacterized protein n=1 Tax=Roseoba...    44   0.005
UniRef50_A4G659 Putative restriction endonuclease n=1 Tax=Hermin...    44   0.005
UniRef50_Q8SDH4 Putative uncharacterized protein n=1 Tax=Lactoba...    44   0.005
UniRef50_A1F1U9 HNH endonuclease domain protein n=1 Tax=Vibrio c...    44   0.006
UniRef50_A5N0L8 Phage-related protein n=15 Tax=Bacteria RepID=A5...    44   0.006
UniRef50_B4SDY4 HNH nuclease n=4 Tax=Bacteria RepID=B4SDY4_PELPB       44   0.006
UniRef50_B9JB56 Putative uncharacterized protein n=1 Tax=Agrobac...    44   0.007
UniRef50_Q1YWU8 Putative uncharacterized protein n=3 Tax=Gammapr...    44   0.007
UniRef50_D1XF45 HNH endonuclease n=3 Tax=Streptomyces RepID=D1XF...    44   0.007
UniRef50_A1REN7 HNH nuclease n=1 Tax=Shewanella sp. W3-18-1 RepI...    44   0.007
UniRef50_B4D4V1 HNH endonuclease n=1 Tax=Chthoniobacter flavus E...    44   0.007
UniRef50_A6FSB3 HNH nuclease n=2 Tax=Roseobacter sp. AzwK-3b Rep...    44   0.007
UniRef50_B0VJM1 Putative ATP dependant helicase yprA n=1 Tax=Can...    44   0.008
UniRef50_B0MB23 Putative uncharacterized protein n=1 Tax=Anaeros...    44   0.008
UniRef50_Q9R669 Group II SELF-splicing intron ORF (Fragments) n=...    44   0.008
UniRef50_C4XM37 Putative uncharacterized protein n=1 Tax=Desulfo...    43   0.010
UniRef50_B0MFF1 Putative uncharacterized protein n=1 Tax=Anaeros...    43   0.010
UniRef50_B2IX42 HNH endonuclease n=18 Tax=Cyanobacteria RepID=B2...    43   0.010
UniRef50_B8I0D2 HNH endonuclease n=1 Tax=Clostridium cellulolyti...    43   0.011
UniRef50_Q2FQI6 HNH endonuclease n=1 Tax=Methanospirillum hungat...    43   0.011
UniRef50_A7I926 HNH endonuclease n=1 Tax=Candidatus Methanoregul...    43   0.011
UniRef50_C4F8E8 Putative uncharacterized protein n=1 Tax=Collins...    43   0.012
UniRef50_UPI0001BC7B91 HNH endonuclease n=1 Tax=Bacteroides sp. ...    43   0.013
UniRef50_Q82CY5 Putative uncharacterized protein n=1 Tax=Strepto...    43   0.013
UniRef50_A9B2D5 HNH endonuclease n=1 Tax=Herpetosiphon aurantiac...    43   0.014
UniRef50_B9MNG3 HNH endonuclease n=1 Tax=Anaerocellum thermophil...    43   0.014
UniRef50_B7GM48 Restriction endonuclease, McrA/HNH family, phage...    43   0.015
UniRef50_C3L8D2 Putative uncharacterized protein n=6 Tax=Bacillu...    43   0.015
UniRef50_C4K5N9 Group II intron encoded reverse transcriptase n=...    42   0.016
UniRef50_B4SCA5 HNH nuclease n=1 Tax=Pelodictyon phaeoclathratif...    42   0.016
UniRef50_A9VH89 HNH endonuclease n=3 Tax=Bacillus cereus group R...    42   0.016
UniRef50_Q4C417 HNH endonuclease n=3 Tax=Crocosphaera watsonii W...    42   0.018
UniRef50_Q21AN9 HNH endonuclease n=1 Tax=Rhodopseudomonas palust...    42   0.018
UniRef50_D2MHK7 HNH endonuclease n=3 Tax=Bacteria RepID=D2MHK7_9...    42   0.019
UniRef50_Q67M53 Conserved domain protein n=1 Tax=Symbiobacterium...    42   0.020
UniRef50_C3X695 Predicted protein n=1 Tax=Oxalobacter formigenes...    42   0.022
UniRef50_A1ZG09 Paclitaxel/taxanoid biosynthesis susceptibility ...    42   0.023
UniRef50_Q6LSI1 Putative uncharacterized protein MLL7993 n=1 Tax...    42   0.024
UniRef50_A5UU02 HNH endonuclease n=16 Tax=Bacteria RepID=A5UU02_...    42   0.024
UniRef50_A9AZQ2 HNH endonuclease n=1 Tax=Herpetosiphon aurantiac...    42   0.026
UniRef50_Q477P3 HNH endonuclease n=1 Tax=Ralstonia eutropha JMP1...    42   0.026
UniRef50_C3AW04 Putative uncharacterized protein n=1 Tax=Bacillu...    42   0.029
UniRef50_B0KIU7 HNH endonuclease n=1 Tax=Pseudomonas putida GB-1...    42   0.031
UniRef50_C3IFK0 5-methylcytosine-specific restriction enzyme A n...    42   0.032
UniRef50_D0FY11 HNH homing endonuclease n=1 Tax=Dunaliella salin...    42   0.033
UniRef50_A0PZM8 HNH endonuclease domain protein n=3 Tax=Bacteria...    41   0.034
UniRef50_B7K703 RNA-directed DNA polymerase (Reverse transcripta...    41   0.035
UniRef50_D1VIW4 HNH endonuclease n=2 Tax=Actinomycetales RepID=D...    41   0.036
UniRef50_A8LGA4 Stress protein n=1 Tax=Frankia sp. EAN1pec RepID...    41   0.037
UniRef50_A7C7H9 HNH endonuclease n=2 Tax=Gammaproteobacteria Rep...    41   0.038
UniRef50_B7IHZ5 HNH endonuclease domain protein n=1 Tax=Thermosi...    41   0.039
UniRef50_C1SP87 Predicted restriction endonuclease n=1 Tax=Denit...    41   0.042
UniRef50_A3Z7E0 HIT family protein n=6 Tax=Synechococcus RepID=A...    41   0.044
UniRef50_Q0SGX7 Possible endonuclease n=37 Tax=Actinomycetales R...    41   0.047
UniRef50_D1P9G2 5-methylcytosine-specific restriction enzyme A n...    41   0.047
UniRef50_C8WNF9 HNH endonuclease n=1 Tax=Eggerthella lenta DSM 2...    41   0.048
UniRef50_B7KJQ0 Reverse transcriptase n=1 Tax=Cyanothece sp. PCC...    41   0.049
UniRef50_C3XKK9 Restriction endonuclease n=1 Tax=Helicobacter wi...    41   0.049
UniRef50_C3IFK4 5-methylcytosine-specific restriction enzyme A n...    41   0.049
UniRef50_C2D7Q9 Putative uncharacterized protein n=1 Tax=Atopobi...    41   0.049
UniRef50_B8FNE6 HNH endonuclease n=6 Tax=Deltaproteobacteria Rep...    41   0.054
UniRef50_Q60BH4 Putative uncharacterized protein n=1 Tax=Methylo...    41   0.055
UniRef50_A6XRX8 Putative uncharacterized protein n=1 Tax=Vibrio ...    41   0.055
UniRef50_B9LX84 HNH endonuclease n=1 Tax=Halorubrum lacusprofund...    41   0.056
UniRef50_C8WWQ2 HNH endonuclease n=27 Tax=Bacteria RepID=C8WWQ2_...    40   0.060
UniRef50_A0YZ73 RNA-directed DNA polymerase n=1 Tax=Lyngbya sp. ...    40   0.061
UniRef50_C0EP64 Putative uncharacterized protein n=1 Tax=Neisser...    40   0.063
UniRef50_A0Y4N4 Putative uncharacterized protein n=1 Tax=Alterom...    40   0.063
UniRef50_Q188V0 Group II intron reverse transcriptase/maturase n...    40   0.064
UniRef50_B5W3B8 HNH endonuclease n=1 Tax=Arthrospira maxima CS-3...    40   0.066
UniRef50_Q8VUW2 Putative uncharacterized protein 5'-methylcytosi...    40   0.071
UniRef50_B2ZY24 HNH endonuclease n=1 Tax=Ralstonia phage RSL1 Re...    40   0.074
UniRef50_B9ZDV6 HNH endonuclease n=1 Tax=Natrialba magadii ATCC ...    40   0.076
UniRef50_Q3EQP7 5-methylcytosine-specific restriction enzyme A n...    40   0.077
UniRef50_Q8YYJ2 Alr0856 protein n=6 Tax=Cyanobacteria RepID=Q8YY...    40   0.078
UniRef50_D2S3N7 Putative uncharacterized protein n=1 Tax=Haloter...    40   0.082
UniRef50_Q9RZ97 TerF-related protein n=1 Tax=Deinococcus radiodu...    40   0.083
UniRef50_B8GWL7 Hypothetical cytosolic protein n=2 Tax=Caulobact...    40   0.091
UniRef50_A2SPF2 Putative uncharacterized protein n=1 Tax=Methano...    40   0.093

>UniRef50_P24200 5-methylcytosine-specific restriction enzyme A n=2 Tax=Escherichia
           coli RepID=MCRA_ECOLI
          Length = 277

 Score =  574 bits (1479), Expect = e-162,   Method: Compositional matrix adjust.
 Identities = 277/277 (100%), Positives = 277/277 (100%)

Query: 1   MHVFDNNGIELKAECSIGEEDGVYGLILESWGPGDRNKDYNIALDYIIERLVDSGVSQVV 60
           MHVFDNNGIELKAECSIGEEDGVYGLILESWGPGDRNKDYNIALDYIIERLVDSGVSQVV
Sbjct: 1   MHVFDNNGIELKAECSIGEEDGVYGLILESWGPGDRNKDYNIALDYIIERLVDSGVSQVV 60

Query: 61  VYLASSSVRKHMHSLDERKIHPGEYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEIPSGNR 120
           VYLASSSVRKHMHSLDERKIHPGEYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEIPSGNR
Sbjct: 61  VYLASSSVRKHMHSLDERKIHPGEYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEIPSGNR 120

Query: 121 TKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPV 180
           TKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPV
Sbjct: 121 TKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPV 180

Query: 181 EVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADT 240
           EVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADT
Sbjct: 181 EVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADT 240

Query: 241 TDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277
           TDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK
Sbjct: 241 TDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277


>UniRef50_A9BU78 HNH endonuclease n=4 Tax=Burkholderiales RepID=A9BU78_DELAS
          Length = 330

 Score =  131 bits (330), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 57/111 (51%), Positives = 75/111 (67%)

Query: 165 LIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPY 224
           L  K  ++P G+  P  + R    + RDP VKAW+L+++ G+CE C  NAPF   DG P+
Sbjct: 217 LENKKQAKPAGNSNPGTIIRQVAQFERDPAVKAWVLKKAAGVCECCSSNAPFESTDGQPF 276

Query: 225 LEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRL 275
           LEVHH+  L+ GG+DT  N VALCPNCHR LHY   AKELIE +++ +NRL
Sbjct: 277 LEVHHIRKLAEGGSDTVSNTVALCPNCHRALHYGMRAKELIESIFIKVNRL 327


>UniRef50_C3K0B7 Putative 5-methylcytosine-specific restriction enzyme n=1
           Tax=Pseudomonas fluorescens SBW25 RepID=C3K0B7_PSEFS
          Length = 237

 Score =  128 bits (322), Expect = 2e-28,   Method: Compositional matrix adjust.
 Identities = 61/133 (45%), Positives = 84/133 (63%), Gaps = 2/133 (1%)

Query: 146 SELSQPTDDESLLNMRVSKLIKKTLSQ-PEGSRKPVEVERLQKVYVRDPMVKAWILQQSK 204
           S+ +  T DE  L  R SKL ++  +Q P+G  +P +V  +   +VRDP V+AW+L+++K
Sbjct: 105 SDDAAQTADEQTLIRRASKLQQQPFTQLPDGIAQPQKVSTVSTAFVRDPKVRAWVLKEAK 164

Query: 205 GICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKEL 264
           GICE CG NAPF + DG P+LEVHHV  L+  G+D   N VALCPNCH+  H S +    
Sbjct: 165 GICEGCGSNAPFEV-DGLPFLEVHHVKHLAQKGSDRISNAVALCPNCHQRCHRSSDRDAF 223

Query: 265 IEMLYVNINRLQK 277
            E LY  + RL +
Sbjct: 224 TEGLYAKVGRLAR 236


>UniRef50_Q2Y8M1 HNH nuclease n=1 Tax=Nitrosospira multiformis ATCC 25196
           RepID=Q2Y8M1_NITMU
          Length = 226

 Score =  122 bits (305), Expect = 2e-26,   Method: Compositional matrix adjust.
 Identities = 57/115 (49%), Positives = 77/115 (66%), Gaps = 8/115 (6%)

Query: 167 KKTLSQPEGSRKP----VEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGN 222
           +K L +P G+ +P    + V +L+    RDP VKAW+LQQ+ G CE+C K APF   DG+
Sbjct: 115 QKDLPKPSGNPRPKRRRISVAQLE----RDPNVKAWVLQQAAGTCESCEKPAPFQGADGS 170

Query: 223 PYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277
           PYLE+H+V  L+ GGAD   N VALCPNCHRE+HY  NA+ +   LY  + RL++
Sbjct: 171 PYLELHYVQGLADGGADAVSNAVALCPNCHREIHYGANAQAVEAWLYDTVQRLER 225


>UniRef50_A0KIQ7 Probable 5-methylcytosine-specific restriction enzyme A n=1
           Tax=Aeromonas hydrophila subsp. hydrophila ATCC 7966
           RepID=A0KIQ7_AERHH
          Length = 246

 Score =  120 bits (302), Expect = 4e-26,   Method: Compositional matrix adjust.
 Identities = 64/140 (45%), Positives = 83/140 (59%), Gaps = 2/140 (1%)

Query: 138 ASIIRGELSEL-SQPTDDESLLNMRVSKL-IKKTLSQPEGSRKPVEVERLQKVYVRDPMV 195
           A II   L EL  QP   ++    +VS+  IK TL  P G ++P +       Y RDP V
Sbjct: 104 APIIERLLCELDGQPYTGKAAFEHQVSRYKIKPTLPMPIGIQEPQQRYGANTSYGRDPKV 163

Query: 196 KAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHREL 255
           KAW+L  + G CE+C + APF+   G+ +LEVHH+  L+ GG+DT  N VALCPNCHREL
Sbjct: 164 KAWVLMTAVGRCESCAQPAPFHATTGDAFLEVHHLRTLAEGGSDTISNTVALCPNCHREL 223

Query: 256 HYSKNAKELIEMLYVNINRL 275
           HY  N  +  E LY  + RL
Sbjct: 224 HYGVNQAQKREALYQALPRL 243


>UniRef50_A6QD09 5-methylcytosine-specific restriction enzyme A n=2
           Tax=delta/epsilon subdivisions RepID=A6QD09_SULNB
          Length = 225

 Score =  115 bits (287), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 55/129 (42%), Positives = 77/129 (59%), Gaps = 5/129 (3%)

Query: 148 LSQPTDDESLLNMRVSKLIKKTLS-QPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGI 206
           LS+P          V KL+ K L  +P+   +P   +     Y RDP + AW+L  +KGI
Sbjct: 98  LSEPVS----FQAEVDKLVHKKLQDKPKAVLEPKRYDIAITKYDRDPQIVAWVLMNAKGI 153

Query: 207 CENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIE 266
           CE C K APF  +DG P+LEVHH+  L+  G+D+  N +A+CPNCHRELHY +N   L+ 
Sbjct: 154 CECCNKEAPFVKDDGVPFLEVHHLRRLADDGSDSITNAIAICPNCHRELHYGQNKDILLT 213

Query: 267 MLYVNINRL 275
            +Y  ++RL
Sbjct: 214 TIYSQVSRL 222


>UniRef50_Q1YK78 Putative 5-methylcytosine-specific restriction enzyme n=1
           Tax=Aurantimonas manganoxydans SI85-9A1
           RepID=Q1YK78_MOBAS
          Length = 125

 Score =  114 bits (286), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 53/117 (45%), Positives = 75/117 (64%), Gaps = 1/117 (0%)

Query: 158 LNMRVSKL-IKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPF 216
           L  RVS+L  + T++ P+G  +P    R   V++RDP VKA++L+++ GICE C   APF
Sbjct: 3   LERRVSRLSARATIAFPKGIVQPKHTTRTTIVFLRDPGVKAYVLRRAGGICEACDFPAPF 62

Query: 217 YLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNIN 273
               G  +LEVHH+ PL+ GG+D   N VALCPNCHR +H++ +A +  E LY  I 
Sbjct: 63  KTALGGDFLEVHHLKPLAEGGSDRAQNAVALCPNCHRAMHHASDAGQRTERLYAKIG 119


>UniRef50_UPI00016A2859 HNH endonuclease n=1 Tax=Burkholderia thailandensis TXDOH
           RepID=UPI00016A2859
          Length = 214

 Score =  110 bits (274), Expect = 7e-23,   Method: Compositional matrix adjust.
 Identities = 51/111 (45%), Positives = 73/111 (65%), Gaps = 2/111 (1%)

Query: 166 IKKTLSQ-PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPY 224
           I+KTL + P+G++ P         +VRD  VKAW+L+++K  CE C + APF   +G P+
Sbjct: 102 IRKTLDERPDGNKAPGTATSTTTSFVRDLKVKAWVLKRAKDNCEACDQPAPFSGANG-PF 160

Query: 225 LEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRL 275
           LEVHH+  L+ GG+DT  N VA+CPNCHR LH+SK+A+   E +Y  +  L
Sbjct: 161 LEVHHLRKLADGGSDTVTNAVAVCPNCHRRLHFSKDARAYRETIYEKVTEL 211


>UniRef50_Q3K870 Putative 5-methylcytosine-specific restriction enzyme n=1
           Tax=Pseudomonas fluorescens Pf0-1 RepID=Q3K870_PSEPF
          Length = 237

 Score =  104 bits (259), Expect = 4e-21,   Method: Compositional matrix adjust.
 Identities = 43/82 (52%), Positives = 56/82 (68%)

Query: 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254
           VK W+L++S+GICE CG+ APF   DG P+LEVHH+  L +GG D T N VALCPNCHR 
Sbjct: 154 VKKWVLKRSQGICEGCGQKAPFQDADGKPFLEVHHLKHLVNGGTDRTSNAVALCPNCHRR 213

Query: 255 LHYSKNAKELIEMLYVNINRLQ 276
            HYS + +E     Y ++  L+
Sbjct: 214 CHYSSDKEEFTAKFYRSVEGLE 235


>UniRef50_C3FAM5 HNH nuclease n=4 Tax=Bacillus cereus group RepID=C3FAM5_BACTU
          Length = 350

 Score =  100 bits (250), Expect = 4e-20,   Method: Compositional matrix adjust.
 Identities = 45/85 (52%), Positives = 58/85 (68%), Gaps = 1/85 (1%)

Query: 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFY-LNDGNPYLEVHHVIP 232
           + +RKP  VE +   Y R+P V A +L+++ G CE C + APF    DG PYLEVHHVIP
Sbjct: 265 KAARKPDVVEVVTTQYKRNPDVIAEVLERANGYCEECKQEAPFKRAKDGTPYLEVHHVIP 324

Query: 233 LSSGGADTTDNCVALCPNCHRELHY 257
           L+ GG D+ +N V LCPNCHR+ HY
Sbjct: 325 LAQGGEDSVENAVGLCPNCHRKAHY 349


>UniRef50_D0KA86 HNH endonuclease n=2 Tax=Enterobacteriaceae RepID=D0KA86_PECWW
          Length = 240

 Score = 99.8 bits (247), Expect = 8e-20,   Method: Compositional matrix adjust.
 Identities = 49/115 (42%), Positives = 68/115 (59%), Gaps = 14/115 (12%)

Query: 144 ELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQS 203
           E+ + SQ T  E   ++ VS               P   E + K++VR+P V A +L ++
Sbjct: 138 EVRKASQLTSKERKQHLAVSNF-------------PEMKEVITKIFVRNPYVVAEVLHRA 184

Query: 204 KGICENCGKNAPFYL-NDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHY 257
           +G CE C +NAPF    DG PYLEVHH +PLS GG DT +N +A+CPNCHR+ H+
Sbjct: 185 QGKCELCKRNAPFLRGKDGTPYLEVHHCVPLSQGGEDTVENAIAVCPNCHRQAHF 239


>UniRef50_D2C2V7 HNH endonuclease n=1 Tax=Dickeya dadantii Ech586 RepID=D2C2V7_DICD5
          Length = 245

 Score = 98.2 bits (243), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 57/131 (43%), Positives = 75/131 (57%), Gaps = 17/131 (12%)

Query: 140 IIRGELSELSQPTDDESL---LNMRVSKLI---------KKTLSQPEGSRKPVEVERLQK 187
           II    SELS+    E+L    N++V+K I         + + S     +K +++E    
Sbjct: 115 IIEFYESELSKTDSFENLTTEFNIQVNKSIADNQRSRQERLSTSPKYPQKKSLQIE---- 170

Query: 188 VYVRDPMVKAWILQQSKGICENCGKNAPFYLN-DGNPYLEVHHVIPLSSGGADTTDNCVA 246
            ++R+P V A +L ++ G CE C  NAPF    D  PYLEVHH  PLS GGADT DN +A
Sbjct: 171 FFIRNPDVVAEVLLRANGKCERCCSNAPFLRKKDNTPYLEVHHKTPLSEGGADTVDNAIA 230

Query: 247 LCPNCHRELHY 257
           LCPNCHR LHY
Sbjct: 231 LCPNCHRYLHY 241


>UniRef50_Q312Y0 HNH nuclease n=1 Tax=Desulfovibrio desulfuricans subsp.
           desulfuricans str. G20 RepID=Q312Y0_DESDG
          Length = 260

 Score = 97.4 bits (241), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 44/75 (58%), Positives = 52/75 (69%), Gaps = 1/75 (1%)

Query: 184 RLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGN-PYLEVHHVIPLSSGGADTTD 242
           R Q V+ R P+V A +L ++ G CE CG  APF     N PYLEVHHV PL+ GGADT  
Sbjct: 173 REQAVFRRSPVVAARVLLRAGGFCECCGAPAPFVSRADNLPYLEVHHVRPLAEGGADTPA 232

Query: 243 NCVALCPNCHRELHY 257
           NC+ALCPNCHR+ HY
Sbjct: 233 NCMALCPNCHRQFHY 247


>UniRef50_D0Z3H8 HNH nuclease n=1 Tax=Photobacterium damselae subsp. damselae CIP
           102761 RepID=D0Z3H8_LISDA
          Length = 278

 Score = 97.1 bits (240), Expect = 6e-19,   Method: Compositional matrix adjust.
 Identities = 44/85 (51%), Positives = 60/85 (70%), Gaps = 1/85 (1%)

Query: 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPF-YLNDGNPYLEVHHVIP 232
           + ++KP  + R+ K Y R+P + A  L ++ GICE CG  APF   ++G PYLEVHH+IP
Sbjct: 193 KANKKPQLISRVVKDYQRNPDIVAEALIRAAGICEACGCQAPFNKKSNGEPYLEVHHLIP 252

Query: 233 LSSGGADTTDNCVALCPNCHRELHY 257
           LS GG D+ DN  +LCPNCHR+LH+
Sbjct: 253 LSKGGEDSLDNVQSLCPNCHRKLHF 277


>UniRef50_A2SMM5 Putative uncharacterized protein n=1 Tax=Methylibium petroleiphilum
           PM1 RepID=A2SMM5_METPP
          Length = 220

 Score = 94.4 bits (233), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 44/85 (51%), Positives = 54/85 (63%), Gaps = 1/85 (1%)

Query: 175 GSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPF-YLNDGNPYLEVHHVIPL 233
           G  KP  V     V++R+P V A +L ++ G CE C ++APF    DG PYLEVHH  PL
Sbjct: 136 GQAKPERVIVQTTVFMRNPAVAAEVLLRANGHCELCRQSAPFKRRKDGTPYLEVHHRKPL 195

Query: 234 SSGGADTTDNCVALCPNCHRELHYS 258
           S GG DT  N +ALCPNCHR  HY+
Sbjct: 196 SDGGNDTVQNAIALCPNCHRRAHYA 220


>UniRef50_C9PPM2 5-methylcytosine-specific restriction enzyme A n=1 Tax=Pasteurella
           dagmatis ATCC 43325 RepID=C9PPM2_9PAST
          Length = 200

 Score = 92.8 bits (229), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 48/115 (41%), Positives = 67/115 (58%), Gaps = 11/115 (9%)

Query: 158 LNMRVSKLIKKTL-SQPEGSRKPVEVERLQKV---------YVRDPMVKAWILQQSKGIC 207
            +    K +KK L   PE  +K ++ ++++K          + RDP V A +L Q+ G+C
Sbjct: 86  FDSEFDKKVKKALHDSPEKRQKRLDRKKIKKPSYSFVKIRQFHRDPDVVAEVLYQANGVC 145

Query: 208 ENCGKNAPFYLN-DGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNA 261
             C K APF    D  PYLEVHH IPLS  G D+  NC+ALCPNCHR++H+  N+
Sbjct: 146 GACKKPAPFNRKVDNMPYLEVHHKIPLSQNGDDSVSNCIALCPNCHRKIHFGNNS 200


>UniRef50_A8ZWC1 HNH endonuclease n=1 Tax=Desulfococcus oleovorans Hxd3
           RepID=A8ZWC1_DESOH
          Length = 303

 Score = 90.9 bits (224), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 41/97 (42%), Positives = 65/97 (67%), Gaps = 3/97 (3%)

Query: 173 PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDG-NPYLEVHHVI 231
           P G  +P ++ R+   Y RDP +++++++++KG CE CG+   F ++DG N YLE HH+I
Sbjct: 201 PPGISEPEKISRMSPSYSRDPKIRSFVIKRAKGRCEYCGEQG-FLMSDGQNYYLEAHHII 259

Query: 232 PLSSGGADTTDNCVALCPNCHRELHYSKNAKEL-IEM 267
            L+  G DT +N +ALCP  HRE H+  N ++L +EM
Sbjct: 260 ALADEGEDTVENVIALCPKHHREAHFGANKEKLEVEM 296


>UniRef50_A6VSV6 HNH endonuclease n=1 Tax=Marinomonas sp. MWYL1 RepID=A6VSV6_MARMS
          Length = 240

 Score = 90.9 bits (224), Expect = 5e-17,   Method: Compositional matrix adjust.
 Identities = 40/71 (56%), Positives = 51/71 (71%), Gaps = 1/71 (1%)

Query: 188 VYVRDPMVKAWILQQSKGICENCGKNAPFYLN-DGNPYLEVHHVIPLSSGGADTTDNCVA 246
           VY R+P V    L+++ G+CE CGK APF  + DG+PYLEVHH+  L+  G DT +N  A
Sbjct: 169 VYQRNPDVITETLERAAGVCERCGKGAPFIRSKDGSPYLEVHHIQRLADNGPDTLENTKA 228

Query: 247 LCPNCHRELHY 257
           LCPNCHRELH+
Sbjct: 229 LCPNCHRELHF 239


>UniRef50_A4SC99 HNH endonuclease n=1 Tax=Chlorobium phaeovibrioides DSM 265
           RepID=A4SC99_PROVI
          Length = 222

 Score = 90.5 bits (223), Expect = 5e-17,   Method: Compositional matrix adjust.
 Identities = 46/120 (38%), Positives = 67/120 (55%), Gaps = 10/120 (8%)

Query: 139 SIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAW 198
           ++I  E +E+++   D S+   R  +++          ++P         Y R+P +   
Sbjct: 111 ALIETETAEIAKSRTDTSV--ARNERILN-------AEKRPKRQRVYSYTYQRNPDIVVE 161

Query: 199 ILQQSKGICENCGKNAPF-YLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHY 257
            L +++G CENC   APF   +DG P+LEVHH+  LS GG DT +N VALCPNCHRE HY
Sbjct: 162 ALHRAEGFCENCKNPAPFKRASDGTPFLEVHHIRSLSDGGEDTLENVVALCPNCHREKHY 221


>UniRef50_C4SUH5 Restriction endonuclease n=1 Tax=Yersinia frederiksenii ATCC 33641
           RepID=C4SUH5_YERFR
          Length = 238

 Score = 90.1 bits (222), Expect = 7e-17,   Method: Compositional matrix adjust.
 Identities = 37/70 (52%), Positives = 51/70 (72%)

Query: 188 VYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVAL 247
            + R+P+V A +L  + G C++C ++APF   DG PYLEVHHV  L++GG D+ +N +AL
Sbjct: 158 TFKRNPLVVAEVLALAGGKCQSCLRDAPFKREDGRPYLEVHHVEWLANGGEDSVENAIAL 217

Query: 248 CPNCHRELHY 257
           CPNCHRE HY
Sbjct: 218 CPNCHREAHY 227


>UniRef50_B5EI94 HNH endonuclease n=1 Tax=Geobacter bemidjiensis Bem
           RepID=B5EI94_GEOBB
          Length = 233

 Score = 89.7 bits (221), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 45/128 (35%), Positives = 68/128 (53%)

Query: 150 QPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICEN 209
           +PT +E  ++   S  I      P+G  +P         Y RD  V+A+++ ++KG CE 
Sbjct: 95  EPTMNEEKVHEFASNAINDLDEIPQGVAEPERSSHTTSSYARDHKVRAYVIARAKGTCEY 154

Query: 210 CGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLY 269
           CG+      N  + YLE HHVI L+  G DT DN +ALCP  H+E H+  N  E+ E + 
Sbjct: 155 CGELGFLMSNGKSYYLEAHHVIALADEGRDTPDNVIALCPKHHKEAHFGINRDEIEEEMM 214

Query: 270 VNINRLQK 277
           + ++ L K
Sbjct: 215 IFLSTLSK 222


>UniRef50_C7HJ98 HNH endonuclease n=1 Tax=Clostridium thermocellum DSM 2360
           RepID=C7HJ98_CLOTM
          Length = 276

 Score = 89.0 bits (219), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 35/69 (50%), Positives = 50/69 (72%)

Query: 188 VYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVAL 247
           V++RD  V  +  +++ G+C+ CG+ APF   +G PYLE HH+  LS GG+DT +N VAL
Sbjct: 187 VFIRDAFVAEYAKRRANGVCQLCGQKAPFNNKEGIPYLECHHIEWLSEGGSDTIENTVAL 246

Query: 248 CPNCHRELH 256
           CPNCHR++H
Sbjct: 247 CPNCHRKMH 255


>UniRef50_C6ANH6 HNH nuclease n=1 Tax=Aggregatibacter aphrophilus NJ8700
           RepID=C6ANH6_AGGAN
          Length = 194

 Score = 88.6 bits (218), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 43/85 (50%), Positives = 57/85 (67%), Gaps = 5/85 (5%)

Query: 176 SRKPVE--VERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDG-NPYLEVHHVIP 232
           S+ P++  +E LQ  + R+P V A +L ++ G CE C K APF       PYLEVHH+IP
Sbjct: 111 SKHPIKKIIEVLQ--FQRNPDVVAEVLVRANGYCEKCKKPAPFIRKANLQPYLEVHHIIP 168

Query: 233 LSSGGADTTDNCVALCPNCHRELHY 257
           LS  G DT +NC+ALCPNCHR+ H+
Sbjct: 169 LSKDGEDTVENCMALCPNCHRQEHF 193


>UniRef50_A3JQK6 HNH nuclease n=1 Tax=Rhodobacterales bacterium HTCC2150
           RepID=A3JQK6_9RHOB
          Length = 371

 Score = 87.4 bits (215), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 48/128 (37%), Positives = 71/128 (55%), Gaps = 8/128 (6%)

Query: 137 WASIIRGE--LSELSQPTDDESLLNMRVSKLIK-----KTLSQPEGSRKPVEVERLQKVY 189
           W +++     LS+L      E+ L  +V K +K     +     +  + P + +    ++
Sbjct: 236 WFTLVEWSDGLSDLQSVAAAETSLVEQVQKSLKLDPKARQKRLADAPKLPEKQKATTTIF 295

Query: 190 VRDPMVKAWILQQSKGICENCGKNAPF-YLNDGNPYLEVHHVIPLSSGGADTTDNCVALC 248
            R+P V A +L ++ G CE C ++APF   +DG PYLEVHH IPL+  G D+ DN VALC
Sbjct: 296 KRNPDVIAEVLFRANGTCEGCRQSAPFDRRSDGTPYLEVHHKIPLAKDGHDSVDNAVALC 355

Query: 249 PNCHRELH 256
           PNCHR  H
Sbjct: 356 PNCHRREH 363


>UniRef50_C2KXT9 Putative uncharacterized protein n=1 Tax=Oribacterium sinus F0268
           RepID=C2KXT9_9FIRM
          Length = 324

 Score = 85.5 bits (210), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 38/97 (39%), Positives = 60/97 (61%), Gaps = 4/97 (4%)

Query: 168 KTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEV 227
           K   +    +K  EVE +Q    R  +V + + +++ G+C+ C K APFY   G  YLE 
Sbjct: 222 KDFDKQHPKKKLTEVEVVQ----RSSLVSSIVKERAAGVCQLCNKPAPFYNKSGEAYLEC 277

Query: 228 HHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKEL 264
           HHV+ ++ GGAD  +N VALCPNCHR++H   +++++
Sbjct: 278 HHVVWIAKGGADEVNNAVALCPNCHRKMHILDDSEDV 314


>UniRef50_B4S2Y7 HNH nuclease n=2 Tax=Proteobacteria RepID=B4S2Y7_ALTMD
          Length = 116

 Score = 85.5 bits (210), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 42/79 (53%), Positives = 54/79 (68%), Gaps = 5/79 (6%)

Query: 180 VEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPF-YLNDGNPYLEVHHVIPLSSGGA 238
           VEV  LQ    R+P V A +L ++KGIC +C   APF    DG+PYLEVHH+  L+ GG 
Sbjct: 41  VEVSVLQ----RNPDVVAEVLFRAKGICGSCKNPAPFSRRKDGSPYLEVHHIQQLAHGGE 96

Query: 239 DTTDNCVALCPNCHRELHY 257
           DT +N +ALCPNCHR+ H+
Sbjct: 97  DTLENAIALCPNCHRQKHF 115


>UniRef50_Q1QEV2 HNH endonuclease n=5 Tax=Gammaproteobacteria RepID=Q1QEV2_PSYCK
          Length = 282

 Score = 85.5 bits (210), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 46/124 (37%), Positives = 65/124 (52%), Gaps = 14/124 (11%)

Query: 148 LSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEV---ERLQKVYVRDPMVKAWILQQSK 204
           +++P+  +SL  +R   L          S  P      E++Q +  R   +K +  +++ 
Sbjct: 157 VTKPSKGKSLQQLREIAL----------SSTPTHASTQEKIQSIQNRSTAIKLYAKKRAN 206

Query: 205 GICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKEL 264
           GICE C + APF    G PYLEVHH+  L+ GGAD   N +ALCP CHR+ HYS N  E 
Sbjct: 207 GICEGCNEIAPFETKSG-PYLEVHHLTRLADGGADLPQNVIALCPTCHRKAHYSLNHLEF 265

Query: 265 IEML 268
              L
Sbjct: 266 NNQL 269


>UniRef50_C0WRI9 Possible HNH endonuclease n=1 Tax=Lactobacillus buchneri ATCC 11577
           RepID=C0WRI9_LACBU
          Length = 193

 Score = 84.3 bits (207), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 42/127 (33%), Positives = 70/127 (55%), Gaps = 1/127 (0%)

Query: 140 IIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEV-ERLQKVYVRDPMVKAW 198
           I   E+   S+   ++++  M + KLI+   +  +G        E    ++VR+   +  
Sbjct: 49  IANKEVLHQSEIKQEQAVKKMPIKKLIESVKTHEQGKTAKTSCREVTTTMFVRNANNRHL 108

Query: 199 ILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258
            L  SKG+C+ CG+ APF    G PYLEVHH+   S GG D  +N +A+CPNCHR++H  
Sbjct: 109 ALYFSKGVCQLCGEPAPFKDKTGQPYLEVHHIDWFSQGGKDVIENEIAICPNCHRKMHII 168

Query: 259 KNAKELI 265
           ++  +++
Sbjct: 169 QDPNDVL 175


>UniRef50_C0N619 HNH endonuclease domain protein n=1 Tax=Methylophaga thiooxidans
           DMS010 RepID=C0N619_9GAMM
          Length = 274

 Score = 82.0 bits (201), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 43/123 (34%), Positives = 66/123 (53%), Gaps = 8/123 (6%)

Query: 155 ESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNA 214
           +SLL +R + L K + ++          ER Q  Y R   ++ ++ +++ G CE C   A
Sbjct: 157 KSLLELREAALEKPSHTKNAS-------ERRQSAYYRSKALRLYVRKRAGGKCEACAVPA 209

Query: 215 PFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINR 274
           PF    G PY+E HH+  ++ GG D   N + LCPNCHR  HY+KN +E  + L   +  
Sbjct: 210 PFESRKG-PYIECHHLHRVADGGPDHPMNVIGLCPNCHRRAHYAKNFREFNDSLKPVVRE 268

Query: 275 LQK 277
           L+K
Sbjct: 269 LEK 271


>UniRef50_C3C627 Restriction endonuclease n=7 Tax=Bacillus RepID=C3C627_BACTU
          Length = 333

 Score = 81.6 bits (200), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 42/111 (37%), Positives = 60/111 (54%), Gaps = 2/111 (1%)

Query: 159 NMRVSKLIKKTLSQPEGSRKPVEVERLQKV--YVRDPMVKAWILQQSKGICENCGKNAPF 216
           N +  KL  + L +      P   +R  K   Y R+  V  +  +++ GICE C + APF
Sbjct: 210 NKKARKLDYQKLKERAKKATPSSNKRYTKTETYQRNEFVAEFSKRRANGICELCEQQAPF 269

Query: 217 YLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEM 267
              +GNPYLE HHV  LS GG DT  N V +C NCHR LH   +  +++++
Sbjct: 270 EDKEGNPYLESHHVEWLSEGGEDTIYNTVGVCANCHRRLHVLNDENDVMKL 320


>UniRef50_Q080H4 HNH endonuclease n=1 Tax=Shewanella frigidimarina NCIMB 400
           RepID=Q080H4_SHEFN
          Length = 309

 Score = 80.1 bits (196), Expect = 8e-14,   Method: Compositional matrix adjust.
 Identities = 41/125 (32%), Positives = 65/125 (52%), Gaps = 9/125 (7%)

Query: 143 GELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQ 202
           GE++E +  +DDE         L ++  ++    + P +       Y R   VK + L+ 
Sbjct: 184 GEINEATFISDDE---------LWERICTENPKRKSPKKTTTETVGYERSEFVKEYALRH 234

Query: 203 SKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAK 262
           + G C+ C    PF    G  +LEVHH+  LS GG D  +N V LCPNCHR++H   +AK
Sbjct: 235 ANGKCQLCNNAGPFATKSGRNFLEVHHIDWLSKGGLDMPENVVGLCPNCHRKMHNINDAK 294

Query: 263 ELIEM 267
           ++ ++
Sbjct: 295 DIKKL 299


>UniRef50_D2S1X8 HNH endonuclease n=1 Tax=Haloterrigena turkmenica DSM 5511
           RepID=D2S1X8_9EURY
          Length = 84

 Score = 79.0 bits (193), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 33/74 (44%), Positives = 48/74 (64%)

Query: 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254
           ++ + LQ + G+C+ C  +APF  +D   +LEVHH+   S+GGAD   N +ALCPNCHR 
Sbjct: 1   MRKYALQVADGVCQGCSDDAPFLTDDRESFLEVHHLRRRSNGGADHPKNVIALCPNCHRR 60

Query: 255 LHYSKNAKELIEML 268
           +H+ +N  E  E L
Sbjct: 61  VHHGRNGDEFNEDL 74


>UniRef50_C9BZK6 Restriction endonuclease (Fragment) n=4 Tax=Firmicutes
           RepID=C9BZK6_ENTFC
          Length = 96

 Score = 78.6 bits (192), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 33/68 (48%), Positives = 45/68 (66%), Gaps = 1/68 (1%)

Query: 189 YVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALC 248
           Y R+P V  ++ + +KGIC+ C +  PF + DG PYL  HH+  LS GG D  +NC+ALC
Sbjct: 4   YKRNPFVSEYVKRLAKGICQLCQEKGPF-IKDGVPYLHCHHIEYLSQGGKDVIENCIALC 62

Query: 249 PNCHRELH 256
           PNCH  +H
Sbjct: 63  PNCHARIH 70


>UniRef50_Q0BZ66 Conserved domain protein n=1 Tax=Hyphomonas neptunium ATCC 15444
           RepID=Q0BZ66_HYPNA
          Length = 343

 Score = 78.6 bits (192), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 44/130 (33%), Positives = 65/130 (50%), Gaps = 5/130 (3%)

Query: 139 SIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAW 198
           ++   E  E  +   D S+ ++R S     T  +   +  P E  R+ +   R   +KA+
Sbjct: 206 AVADSETDEEIEDQPDTSIDDLRTSAYEAATAVR---NSNPKEARRVYRQ--RSAKIKAY 260

Query: 199 ILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258
           IL ++ G+CE  G+ APF    G+PYLEVHH   LS  G D      A+ P  HRE+H+ 
Sbjct: 261 ILARAGGVCELTGEKAPFLTKSGHPYLEVHHTQRLSDDGLDHPRWVAAISPTAHREIHFG 320

Query: 259 KNAKELIEML 268
           +   EL E L
Sbjct: 321 ERGDELNERL 330


>UniRef50_C4WNE8 Putative uncharacterized protein n=1 Tax=Ochrobactrum intermedium
           LMG 3301 RepID=C4WNE8_9RHIZ
          Length = 282

 Score = 77.8 bits (190), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 40/124 (32%), Positives = 61/124 (49%), Gaps = 2/124 (1%)

Query: 145 LSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSK 204
           L  + +  DDE  +       ++    Q  GSR+     R   +Y R   V+ ++L ++ 
Sbjct: 148 LENIVEAVDDEQPVPAVDLAAMRDLARQAAGSREGKASTR--TIYERSRHVRDYVLARAN 205

Query: 205 GICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKEL 264
           G CE C   APF   +G PYLE HH+  +S GG D     +ALCP CHR++H+ +     
Sbjct: 206 GHCEGCSCQAPFLRINGQPYLEPHHIRRVSDGGPDDPSYVIALCPTCHRKVHHGQGGATY 265

Query: 265 IEML 268
            + L
Sbjct: 266 NDTL 269


>UniRef50_A9F818 Putative restriction endonuclease n=1 Tax=Phaeobacter gallaeciensis
           2.10 RepID=A9F818_9RHOB
          Length = 220

 Score = 71.6 bits (174), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 32/70 (45%), Positives = 43/70 (61%), Gaps = 1/70 (1%)

Query: 188 VYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVAL 247
           V+VR+      + Q + G+C+ C K   F    G+ +LEVHH   LS GG DT +N VAL
Sbjct: 146 VFVRNSEFSRRVRQAANGVCDAC-KGKTFQTQSGDWFLEVHHKKWLSEGGTDTIENMVAL 204

Query: 248 CPNCHRELHY 257
           CPNCHR+ H+
Sbjct: 205 CPNCHRQEHF 214


>UniRef50_B1ZMM6 HNH endonuclease n=1 Tax=Opitutus terrae PB90-1 RepID=B1ZMM6_OPITP
          Length = 279

 Score = 69.3 bits (168), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 31/74 (41%), Positives = 47/74 (63%), Gaps = 5/74 (6%)

Query: 191 RDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPN 250
           R+P V+ W+L++S+G+CE  G +          +L+VHH++  + G  D   NCVALCPN
Sbjct: 194 RNPKVRRWVLKRSRGVCERLGCHITRSFAG---FLDVHHILGAAKG--DRVWNCVALCPN 248

Query: 251 CHRELHYSKNAKEL 264
           CHRE H + N K++
Sbjct: 249 CHRETHCAPNRKKI 262


>UniRef50_Q1L9I8 HNH nuclease n=2 Tax=cellular organisms RepID=Q1L9I8_RALME
          Length = 348

 Score = 65.1 bits (157), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 39/100 (39%), Positives = 55/100 (55%), Gaps = 17/100 (17%)

Query: 175 GSRKPVEVERLQKVYV-RDPMVKAWILQQSKGICEN--CGKNAPFYLNDGNPYLEVHHVI 231
           GS  P E    ++ YV RD  V+  +L ++ G+CEN  C   APF       +L+VHH+ 
Sbjct: 248 GSDSP-ERRTAERSYVKRDDRVRRQVLDRADGVCENPTCSIRAPF-----PSFLDVHHIF 301

Query: 232 PLSSGGADTTD---NCVALCPNCHRELHYSKNAKELIEML 268
                G +T+D   NCVA+CPNCHR  HY+ +   + E L
Sbjct: 302 -----GVETSDRAWNCVAICPNCHRAAHYAPDRSAINEEL 336


>UniRef50_A8R8M0 Putative uncharacterized protein n=1 Tax=Eubacterium dolichum DSM
           3991 RepID=A8R8M0_9FIRM
          Length = 508

 Score = 65.1 bits (157), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 37/96 (38%), Positives = 52/96 (54%), Gaps = 6/96 (6%)

Query: 188 VYVRDPMVKAWILQQSKGICENCGKNAPFYL-NDGNPYLEVHHVIPLSSG-----GADTT 241
           +Y R+       +  SK  CE   K+  F   NDG PY+E HH+IP+S         D  
Sbjct: 396 IYKRERKRANNAIIHSKHQCEIDAKHISFKRKNDGFPYMEAHHLIPMSKQDLFEYSLDVE 455

Query: 242 DNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277
           +N V+LC  CHRE+H+ +NA  LI+ LY +  +L K
Sbjct: 456 ENIVSLCSQCHREIHHGENADALIKKLYNDRKKLLK 491


>UniRef50_Q3K789 Putative HNH endonuclease n=1 Tax=Pseudomonas fluorescens Pf0-1
           RepID=Q3K789_PSEPF
          Length = 323

 Score = 64.7 bits (156), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 37/111 (33%), Positives = 60/111 (54%), Gaps = 13/111 (11%)

Query: 162 VSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICE--NCGKNAPFYLN 219
           V+ L    L + E SR    V R+     RDP V+  ++ +  G CE   CG +  +   
Sbjct: 212 VAGLDLSLLGRDEASRYQATVSRV----ARDPSVRKAVIDRCNGRCERPGCGASRSY--- 264

Query: 220 DGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYV 270
             + +L+VHH++ +    +D   NCVALCPNCHR+ H+S + ++L + L +
Sbjct: 265 --SGFLDVHHILGVEI--SDRVANCVALCPNCHRDAHFSADRQKLNDSLLI 311


>UniRef50_Q9L0M9 Putative uncharacterized protein SCO4631 n=3 Tax=Streptomyces
           RepID=Q9L0M9_STRCO
          Length = 560

 Score = 64.3 bits (155), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 34/91 (37%), Positives = 45/91 (49%), Gaps = 2/91 (2%)

Query: 189 YVRDPMVKAWILQQSKGICEN--CGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVA 246
           YVRDP  +  +L++ +  CEN  C  +       G P L+V HV  L+ GG D   N +A
Sbjct: 466 YVRDPSARGAVLKRCQKRCENPECAGHPTELTKAGLPILQVDHVNDLAKGGPDVPWNMIA 525

Query: 247 LCPNCHRELHYSKNAKELIEMLYVNINRLQK 277
           LCPNCH    Y  N   L  +L     RL +
Sbjct: 526 LCPNCHALKTYGANKVRLQRLLAATARRLHE 556


>UniRef50_B0N4T9 Putative uncharacterized protein n=1 Tax=Clostridium ramosum DSM
           1402 RepID=B0N4T9_9FIRM
          Length = 329

 Score = 63.5 bits (153), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 39/99 (39%), Positives = 51/99 (51%), Gaps = 7/99 (7%)

Query: 178 KPVEVE-RLQKVYVRDPMVKAWILQQSKGICE-NCGKNAPFYLNDGNPYLEVHHVIPLS- 234
           KP  VE +  KVY R+  V    L  +   CE +          DG PY E HH+IP++ 
Sbjct: 206 KPKLVENKFNKVYKRNKAVAINALGIANFSCEIDKKHKTFKRKKDGVPYTEPHHLIPMAF 265

Query: 235 ----SGGADTTDNCVALCPNCHRELHYSKNAKELIEMLY 269
                   D  +N V+LC NCH E+HY +NA+ELI  LY
Sbjct: 266 QDEFDFSIDIEENIVSLCSNCHNEIHYGENARELITKLY 304


>UniRef50_Q0KFQ5 Predicted restriction endonuclease n=1 Tax=Ralstonia eutropha H16
           RepID=Q0KFQ5_RALEH
          Length = 371

 Score = 60.5 bits (145), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 36/98 (36%), Positives = 53/98 (54%), Gaps = 9/98 (9%)

Query: 189 YVRDPMVKAWILQQSKGICENCGKNAPFYLNDGN-PYLEVHHVIPLSSGG-----ADTTD 242
           Y RDP+V A  ++ ++  CE   ++  F  +  N PY+E HH+IPLS         D T 
Sbjct: 251 YPRDPLVAAEAVKSAEYRCELFPEHQTFKSSSKNVPYVEAHHLIPLSRQADFQFSLDITA 310

Query: 243 NCVALCPNCHRELHY---SKNAKELIEMLYVNINRLQK 277
           N +ALCP CH+ LH+   S+    L  +L    +RLQ+
Sbjct: 311 NIIALCPTCHQRLHHGHASERRSPLRRLLSQRKDRLQE 348


>UniRef50_A3US95 Putative restriction endonuclease n=1 Tax=Vibrio splendidus 12B01
           RepID=A3US95_VIBSP
          Length = 259

 Score = 60.1 bits (144), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 36/111 (32%), Positives = 55/111 (49%), Gaps = 5/111 (4%)

Query: 153 DDESLLNMRVSKLIKKTLSQ-----PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGIC 207
           D +S+ ++RV K  K T+ +      +G +     ++    Y R+  V     + +KG C
Sbjct: 146 DRDSVESVRVRKAKKLTVEELQALAAKGRKTATRYQQKSTSYERNIWVAELAKRLAKGQC 205

Query: 208 ENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258
           + C K APF    G PYLE HH+  LS GG DT +N   + P   +E  +S
Sbjct: 206 QLCLKPAPFKNTKGEPYLETHHIAWLSKGGEDTAENTSRIVPQLPQENAHS 256


>UniRef50_D1NJY2 Transcriptional regulator, XRE family n=1 Tax=Clostridium
           thermocellum JW20 RepID=D1NJY2_CLOTM
          Length = 446

 Score = 58.5 bits (140), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 30/89 (33%), Positives = 49/89 (55%), Gaps = 8/89 (8%)

Query: 189 YVRDPMVKAWILQQSKGICENCGKNAPFYLNDGN-PYLEVHHVIPLSSGGA-----DTTD 242
           ++R+P V    L++++  CE    +  F     N PY+E HH+IP+S+        D T 
Sbjct: 332 FLRNPKVAIQALKKAQYKCEINDAHETFIAKSSNKPYVESHHLIPISNSAMFGFSIDITA 391

Query: 243 NCVALCPNCHRELHYSKN--AKELIEMLY 269
           N  +LCPNCHR +H + +   +E++  LY
Sbjct: 392 NICSLCPNCHRAIHSATDEVKREMLTKLY 420


>UniRef50_D1BJK4 HNH endonuclease n=1 Tax=Sanguibacter keddieii DSM 10542
           RepID=D1BJK4_SANKS
          Length = 395

 Score = 58.2 bits (139), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 43/118 (36%), Positives = 61/118 (51%), Gaps = 11/118 (9%)

Query: 164 KLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICEN--CGKNAPFYLN-D 220
           +L+++ L+  E + +P  V R+   Y R    +  +L +S G CE+  C    P  LN  
Sbjct: 271 ELVRR-LADLERTTEPQTVSRI--AYQRQYAARRAVLIRSAGQCESERC-TGMPAELNRK 326

Query: 221 GNPYLEVHHVIPLSSGGADTTDNCVALCPNCH----RELHYSKNAKELIEMLYVNINR 274
           G P L+V H++ LS GGAD   N VALCPNCH    R  H  +  KEL  +     +R
Sbjct: 327 GMPILDVDHIVELSQGGADHPLNMVALCPNCHAAKTRGQHAKRWEKELRRIAQAAHDR 384


>UniRef50_A3U4A6 E14 prophage-like protein n=1 Tax=Oceanicola batsensis HTCC2597
           RepID=A3U4A6_9RHOB
          Length = 201

 Score = 58.2 bits (139), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 37/107 (34%), Positives = 53/107 (49%), Gaps = 18/107 (16%)

Query: 161 RVSKLIKKTLSQPEGSRKPVEVERLQKVY---------VRDPMVKAWILQQSKGICENCG 211
           R  + I   L Q + S +  EV++ QKV          VRD       L++    C+  G
Sbjct: 58  RTEEAIAADLFQDDSSSE--EVKKTQKVIETFERNRKAVRD-------LKRLYKTCQVTG 108

Query: 212 KNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258
            +  F   +G PYLEVHH++PL  GG+D   N V +  + HR LHY+
Sbjct: 109 DDFVFSKVNGEPYLEVHHLVPLGEGGSDDPANLVVISAHIHRMLHYA 155


>UniRef50_A0YK66 Putative uncharacterized protein n=1 Tax=Lyngbya sp. PCC 8106
           RepID=A0YK66_9CYAN
          Length = 245

 Score = 57.8 bits (138), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 26/57 (45%), Positives = 34/57 (59%), Gaps = 4/57 (7%)

Query: 204 KGICE--NCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258
           KG C+  +CG    F   +G+ Y E HH++PLS GG+    N V LCPN HR  HY+
Sbjct: 166 KGCCQIKDCG--FTFIQKNGDNYAEAHHLVPLSEGGSQDASNVVILCPNHHRMFHYA 220


>UniRef50_C6LDW0 Product McrA n=1 Tax=Bryantella formatexigens DSM 14469
           RepID=C6LDW0_9FIRM
          Length = 380

 Score = 55.8 bits (133), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 28/61 (45%), Positives = 34/61 (55%), Gaps = 7/61 (11%)

Query: 216 FYLNDGNPYLEVHHVIPLSSGGA-----DTTDNCVALCPNCHRELHYS--KNAKELIEML 268
           F   DG PYLEVHH+IPL    A     DT  N + LCP CHR LH+    +  E++  L
Sbjct: 297 FLKPDGTPYLEVHHLIPLKQQPAFEYKLDTMANLIPLCPLCHRRLHHGCRADVDEMLTQL 356

Query: 269 Y 269
           Y
Sbjct: 357 Y 357


>UniRef50_C0ZFI2 Putative uncharacterized protein n=1 Tax=Brevibacillus brevis NBRC
           100599 RepID=C0ZFI2_BREBN
          Length = 360

 Score = 55.5 bits (132), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 29/61 (47%), Positives = 40/61 (65%), Gaps = 8/61 (13%)

Query: 224 YLEVHHVIP-----LSSGGADTTDNCVALCPNCHRELHYSKNA--KELIEMLYV-NINRL 275
           ++E HH+IP     L S   D   N V+LCPNCHR++H++  +  KELIE+LY   INRL
Sbjct: 283 FVEAHHLIPMKLQALFSWSLDVPGNIVSLCPNCHRKIHHASKSERKELIEVLYSKKINRL 342

Query: 276 Q 276
           +
Sbjct: 343 K 343


>UniRef50_A3WFM1 5-methylcytosine-specific restriction enzyme A n=1
           Tax=Erythrobacter sp. NAP1 RepID=A3WFM1_9SPHN
          Length = 288

 Score = 55.1 bits (131), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 45/172 (26%), Positives = 70/172 (40%), Gaps = 39/172 (22%)

Query: 136 FWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEG----------------SRKP 179
           FW    RG+   L Q TD      + + ++ K  L+  +G                 + P
Sbjct: 114 FWGVFERGDDIWLFQATD------VFMDRIRKHGLASEDGGSILEPEVDDYQSEINQKAP 167

Query: 180 VEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFY-LNDGNPYLEVHHVIPLSSGG- 237
            ++   QK + RDP V A  L+ +   CE   +   F   + G P++E HH+IP+ +   
Sbjct: 168 SQITSTQKAWSRDPKVAAEALKNASFECELYPELPTFTSRSTGYPFMEAHHLIPMKAQAD 227

Query: 238 ----ADTTDNCVALCPNCHRELHYSKN-----------AKELIEMLYVNINR 274
                D  DN   L P  HR+LH ++            AK    + YVNI +
Sbjct: 228 FDVSLDVVDNICCLSPFAHRKLHMAEFDDIIDDLERLIAKRAALLDYVNITK 279


>UniRef50_Q81E47 5-methylcytosine-specific restriction enzyme A n=15 Tax=Bacillus
           cereus group RepID=Q81E47_BACCR
          Length = 97

 Score = 55.1 bits (131), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 31/96 (32%), Positives = 51/96 (53%), Gaps = 8/96 (8%)

Query: 182 VERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNP-YLEVHHVIPLS-----S 235
           +E  ++V+ RDP      ++Q++  CE    +  F        Y+E HH+IPL       
Sbjct: 1   MESGREVWPRDPKKAKQAIKQAEFKCEIDDTHETFVSEASRKNYMEAHHLIPLRMQHDFE 60

Query: 236 GGADTTDNCVALCPNCHRELHY--SKNAKELIEMLY 269
              D   N V++CPNCHR +HY   K+ K+++E+L+
Sbjct: 61  NSLDVVGNIVSICPNCHRLIHYGRDKDKKKVLELLF 96


>UniRef50_Q723Z7 Conserved domain protein n=4 Tax=Listeria monocytogenes
           RepID=Q723Z7_LISMF
          Length = 284

 Score = 54.7 bits (130), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 29/78 (37%), Positives = 43/78 (55%), Gaps = 7/78 (8%)

Query: 206 ICENCGKNAPFY-LNDGNPYLEVHHVIPLS-----SGGADTTDNCVALCPNCHRELHYSK 259
           +CE   ++  F  + DG PY+E HH+IP++         D  DN + LCP CHR++HY+ 
Sbjct: 187 VCEFNQEHKTFINIKDGKPYVEGHHLIPMAVQDYYDNTIDFADNIICLCPTCHRKIHYAV 246

Query: 260 NAKELIEMLYVNINRLQK 277
            + E  EML    N  +K
Sbjct: 247 QS-EKKEMLIKIFNEREK 263


>UniRef50_C4L074 HNH endonuclease n=1 Tax=Exiguobacterium sp. AT1b
           RepID=C4L074_EXISA
          Length = 272

 Score = 54.7 bits (130), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 34/104 (32%), Positives = 49/104 (47%), Gaps = 4/104 (3%)

Query: 165 LIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPY 224
           ++K+ L +  GS   +   R Q++  R   V   IL ++   CE CG  +PF   DG  Y
Sbjct: 158 IVKQNLQKVSGSSTAI---RKQQIRERSAAVYYSILARANNHCEACGSPSPFETEDG-AY 213

Query: 225 LEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEML 268
           LE+H +   S           A+CPNCH  LH  K+  +  E L
Sbjct: 214 LELHSLYSHSDQIILLPGLGAAVCPNCHMRLHKGKDRSQYNEQL 257


>UniRef50_B5G9G0 HNH endonuclease n=1 Tax=Streptomyces sp. SPB74 RepID=B5G9G0_9ACTO
          Length = 272

 Score = 53.5 bits (127), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 30/82 (36%), Positives = 43/82 (52%), Gaps = 4/82 (4%)

Query: 197 AWILQQSKGI-CENCGKN-APFYLNDGNPYLEVHHVIPLSSGGADTT--DNCVALCPNCH 252
           A +L+Q   + CE CG +   FY   G+ Y+E HHV+PL   G  TT   +   +C NCH
Sbjct: 171 ASVLKQGGALSCEACGFDFGKFYGERGDGYIECHHVVPLHEAGEGTTRLADLALICSNCH 230

Query: 253 RELHYSKNAKELIEMLYVNINR 274
           R +H S       E+  V ++R
Sbjct: 231 RMIHRSAPWPTPAELRLVVLDR 252


>UniRef50_B8KVR3 HNH endonuclease domain protein n=1 Tax=gamma proteobacterium
           NOR51-B RepID=B8KVR3_9GAMM
          Length = 289

 Score = 53.1 bits (126), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 35/117 (29%), Positives = 51/117 (43%), Gaps = 16/117 (13%)

Query: 167 KKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICE-NCGKNAPFYLNDGNPYL 225
           +K ++ PE +  P E   ++  Y R   V    L+ +   CE +     P     G P +
Sbjct: 158 QKLVAAPEDAVVPKEYRAMR--YERSAAVGREALESAGYACEFDNTHETPLSAVTGQPIM 215

Query: 226 EVHHVIPLSSGGA-----DTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277
           EVHH++P+S         D   N V+LCPNCH  +H S           V +  LQK
Sbjct: 216 EVHHLVPISKSAEFRCSLDVLANVVSLCPNCHSAIHRSTKT--------VQVAMLQK 264


>UniRef50_B3CDE4 Putative uncharacterized protein n=1 Tax=Bacteroides intestinalis
           DSM 17393 RepID=B3CDE4_9BACE
          Length = 261

 Score = 52.0 bits (123), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 31/92 (33%), Positives = 50/92 (54%), Gaps = 10/92 (10%)

Query: 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIP 232
           EGS +   V R    Y R+P+ +   +++   IC+ CG + +  Y   GN ++ VHH++P
Sbjct: 162 EGSLQQALVNR----YERNPIARKKCIEKHGCICQVCGMDFSKVYGELGNGFIHVHHIVP 217

Query: 233 LSS--GGA---DTTDNCVALCPNCHRELHYSK 259
           +S+  G A   +  +  V +CPNCH  LH  K
Sbjct: 218 ISALKGEAHKIEPENGLVPVCPNCHAMLHKGK 249


>UniRef50_B1ZSH9 Restriction endonuclease-like protein n=1 Tax=Opitutus terrae
           PB90-1 RepID=B1ZSH9_OPITP
          Length = 261

 Score = 51.6 bits (122), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 11/110 (10%)

Query: 165 LIKKTLSQPEGSRKP----VEVERLQKVYVRDPMVKAWILQQSKGICENCG-KNAPFYLN 219
           L++    +PEG  +P    V ++RL+     DP  +   ++    +C+ CG +    Y  
Sbjct: 139 LVRGDFEEPEGFFRPGVATVVIDRLEH----DPFARRACIEHYGSVCQACGMRFDKVYGK 194

Query: 220 DGNPYLEVHHVIPLSS--GGADTTDNCVALCPNCHRELHYSKNAKELIEM 267
            G  ++EVH + P+S     AD     + LC NCHR +H    A  + E+
Sbjct: 195 IGAGFIEVHRLRPVSRPVDSADPVKELIPLCSNCHRMIHRRSPALSVAEL 244


>UniRef50_C9XQW3 Putative uncharacterized protein n=2 Tax=Clostridium difficile
           RepID=C9XQW3_CLODC
          Length = 375

 Score = 51.2 bits (121), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 41/130 (31%), Positives = 62/130 (47%), Gaps = 13/130 (10%)

Query: 136 FWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMV 195
           F A I    L E+SQ    ++ LN+    +  +T  + EG  K V      K Y R+P  
Sbjct: 238 FTAEIEDDVLEEISQ----DNPLNINTINIELETEIRKEGKVKYV----YGKQYERNPRN 289

Query: 196 KAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSSGGADTTDN----CVALCPN 250
           +   ++     C  CG +    Y + G  Y+E+HH+ PLSS G ++  N     V +C N
Sbjct: 290 RIEAIKYHGTKCIVCGFDFEKTYGDRGKGYIEIHHIKPLSSVGEESNINPKTDLVPICSN 349

Query: 251 CHRELHYSKN 260
           CHR +H  K+
Sbjct: 350 CHRMIHRKKD 359


>UniRef50_B0ACA5 Putative uncharacterized protein n=1 Tax=Clostridium bartlettii DSM
           16795 RepID=B0ACA5_9CLOT
          Length = 305

 Score = 50.8 bits (120), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 31/98 (31%), Positives = 49/98 (50%), Gaps = 7/98 (7%)

Query: 187 KVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNP-YLEVHHVIPLSSG-----GADT 240
           K Y+RD  V    L+++   CE   ++  F   +    Y E HH++P++         D 
Sbjct: 193 KTYIRDRKVAMNALKKANHKCEVDSEHEVFLRRNVEVGYTESHHLVPMAYSDIFDVSLDV 252

Query: 241 TDNCVALCPNCHRELHYSKNAKELIEMLYVN-INRLQK 277
            +N V+LC +CH  LHY K  + ++E LY   +N L K
Sbjct: 253 EENIVSLCSHCHNLLHYGKEFERVLEQLYYERVNHLNK 290


>UniRef50_Q39IU3 Putative uncharacterized protein n=1 Tax=Burkholderia sp. 383
           RepID=Q39IU3_BURS3
          Length = 122

 Score = 50.8 bits (120), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 20/53 (37%), Positives = 32/53 (60%)

Query: 199 ILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNC 251
           +L +++  CE CG  A +   DG P+L+ HH+  L+   +DT  N  ++CPNC
Sbjct: 23  LLDRAETTCEACGHPATYSGADGFPFLDTHHLRKLTDSESDTVTNAFSVCPNC 75


>UniRef50_C3GU40 HNH endonuclease n=2 Tax=Bacillus thuringiensis RepID=C3GU40_BACTU
          Length = 622

 Score = 50.8 bits (120), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 15/81 (18%)

Query: 176 SRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSS 235
           +RKPV           DP++K   L +    C  CG     +L+     +  HH++P+ +
Sbjct: 466 NRKPV-----------DPIIKQQTLARDDYRCRCCGTGGKAFLS----TIIFHHIVPVHA 510

Query: 236 GGADTTDNCVALCPNCHRELH 256
           GG DT  N + LC +CH  LH
Sbjct: 511 GGPDTVANGLTLCDSCHITLH 531


>UniRef50_Q3EYN0 HNH endonuclease family protein n=1 Tax=Bacillus thuringiensis
           serovar israelensis ATCC 35646 RepID=Q3EYN0_BACTI
          Length = 422

 Score = 50.4 bits (119), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 15/81 (18%)

Query: 176 SRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSS 235
           +RKPV           DP++K   L +    C  CG     +L+     +  HH++P+ +
Sbjct: 266 NRKPV-----------DPIIKQQTLARDDYRCRCCGTGGKAFLS----TIIFHHIVPVHA 310

Query: 236 GGADTTDNCVALCPNCHRELH 256
           GG DT  N + LC +CH  LH
Sbjct: 311 GGPDTVANGLTLCDSCHITLH 331


>UniRef50_Q6MJA3 Putative membrane protein n=1 Tax=Bdellovibrio bacteriovorus
           RepID=Q6MJA3_BDEBA
          Length = 140

 Score = 50.4 bits (119), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 30/94 (31%), Positives = 47/94 (50%), Gaps = 7/94 (7%)

Query: 176 SRKPVEVERLQKVYVRDPMVKAWILQQ-SKGICENCGKNAPFYLNDGNPYLEVHHVIPLS 234
           S  P E ++ +K   R+     W  Q+  KG+C +CGK   F   D    L + H+IP++
Sbjct: 34  SAAPPEHQKREKAKARELRQSQWWKQELGKGLCYHCGKR--FKPAD----LTMDHLIPIA 87

Query: 235 SGGADTTDNCVALCPNCHRELHYSKNAKELIEML 268
            GG    +NCV  C +C+ +  Y   A+  +E L
Sbjct: 88  RGGKSNKNNCVPSCKDCNSKKGYKTRAEMALEEL 121


>UniRef50_B3EB35 HNH endonuclease n=1 Tax=Geobacter lovleyi SZ RepID=B3EB35_GEOLS
          Length = 281

 Score = 50.1 bits (118), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 34/97 (35%), Positives = 46/97 (47%), Gaps = 9/97 (9%)

Query: 173 PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVI 231
           PEG+   V V +    Y R P+ +A  +     +C  CG +    Y   G  Y+EVHH I
Sbjct: 177 PEGACIKVIVNK----YERSPVNRAVCIAVYGTVCHVCGFDFGKVYGQIGKGYIEVHHRI 232

Query: 232 PLSSGGA----DTTDNCVALCPNCHRELHYSKNAKEL 264
           P+S  GA    D   + V LC NCH  +H +    EL
Sbjct: 233 PVSKMGASYVIDPIRDLVPLCSNCHSAVHRTDPPVEL 269


>UniRef50_C0QGN0 Putative 5-methylcytosine-specific restriction enzyme A n=1
           Tax=Desulfobacterium autotrophicum HRM2
           RepID=C0QGN0_DESAH
          Length = 375

 Score = 49.7 bits (117), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 31/99 (31%), Positives = 50/99 (50%), Gaps = 9/99 (9%)

Query: 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIP 232
           EG+++ V + +    Y RD   +   ++     C+ CG +    Y   G  Y+ VHH+IP
Sbjct: 275 EGAKQTVTINK----YERDHNARKACIEYHGYNCKVCGFDFEKTYGELGRNYIHVHHLIP 330

Query: 233 LSSGGADTTDN----CVALCPNCHRELHYSKNAKELIEM 267
           LS  G + + N     + +CPNCH  LH S+N  +L  +
Sbjct: 331 LSKIGKEYSINPQTDLIPVCPNCHAMLHKSENPNDLYSL 369


>UniRef50_A6TVA6 HNH endonuclease n=6 Tax=Bacteria RepID=A6TVA6_ALKMQ
          Length = 124

 Score = 49.3 bits (116), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 31/94 (32%), Positives = 49/94 (52%), Gaps = 15/94 (15%)

Query: 164 KLIKKTLSQPEGSRKPVEVERLQKVY--VRDPMVKAWILQQSKGICENCGKNAPFYLNDG 221
           K++ K  +Q +  R P   +R  + +  +RD  +KA  L      CE C +N      + 
Sbjct: 29  KVVTKRYNQYQ--RDPASNKRYGRSWKRIRDRYIKAHPL------CEECDRNGRIKAAE- 79

Query: 222 NPYLEVHHVIPLSSGGADTTDNCVALCPNCHREL 255
               EVHH++PLS GG + T N +ALC +CH ++
Sbjct: 80  ----EVHHILPLSKGGGNETSNLMALCKSCHSKI 109


>UniRef50_Q64YP3 Putative uncharacterized protein n=1 Tax=Bacteroides fragilis
           RepID=Q64YP3_BACFR
          Length = 216

 Score = 49.3 bits (116), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 33/104 (31%), Positives = 52/104 (50%), Gaps = 9/104 (8%)

Query: 173 PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIP 232
           PE +R   ++ R  +  +R+  +   +  +   +C+ CG      + +   Y EVHH+ P
Sbjct: 96  PEEAR---QIRREIEAILRNQKLVDELKIRYNNVCQICG--TQIKIGENKYYSEVHHIWP 150

Query: 233 LSS--GGADTTDNCVALCPNCHRELHYSKNA--KELIEMLYVNI 272
           L     G+DT DN V +CPNCH  L Y      KE+ ++L  NI
Sbjct: 151 LGKPHNGSDTLDNMVCVCPNCHTLLDYKAIHLNKEIFKVLKHNI 194


>UniRef50_UPI0001A457FB putative 5-methylcytosine-specific restriction enzyme A n=1
           Tax=Neisseria subflava NJ9703 RepID=UPI0001A457FB
          Length = 255

 Score = 48.9 bits (115), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 38/108 (35%), Positives = 55/108 (50%), Gaps = 10/108 (9%)

Query: 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIP 232
           EGS + V V R    Y RDP  +   L++    C  C  N   FY   G  ++ VHH+ P
Sbjct: 150 EGSVQQVMVNR----YERDPKAREACLKKYGYNCSVCNFNFEDFYGEIGKNFIHVHHLTP 205

Query: 233 LSSGGADTTD---NCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277
           +S+ G   T+   +   +CPNCH  LH + N  + IE L + I ++QK
Sbjct: 206 VSNNGERYTNPEKDLRPVCPNCHAMLHKT-NRPQRIEDLKLLI-KMQK 251


>UniRef50_Q3IBU7 Putative HNH endonuclease n=1 Tax=Pseudoalteromonas haloplanktis
           TAC125 RepID=Q3IBU7_PSEHT
          Length = 420

 Score = 48.5 bits (114), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 6/65 (9%)

Query: 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254
           VKA++LQ+    C++  K         N  L VHH +  S GG D   N +ALC  CH +
Sbjct: 184 VKAYVLQRDNYKCQSGRKT------KHNAKLHVHHKVFRSQGGTDALSNLIALCETCHND 237

Query: 255 LHYSK 259
           LH  K
Sbjct: 238 LHVGK 242


>UniRef50_Q65MN2 McrA n=2 Tax=Bacillus subtilis group RepID=Q65MN2_BACLD
          Length = 140

 Score = 48.1 bits (113), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 29/108 (26%), Positives = 55/108 (50%), Gaps = 8/108 (7%)

Query: 170 LSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGN-PYLEVH 228
           +SQ     +P+  +  Q+ + R+  + +  +  S   CE    +  F     N PY+E H
Sbjct: 5   VSQKRKRPQPIINQGGQRHWTRNASLASKAMMLSNYTCEIDHTHRTFISKSTNMPYVECH 64

Query: 229 HVIPLSSGGA-----DTTDNCVALCPNCHRELHYSKN--AKELIEMLY 269
           H++P++         D   N V+LCP+CHR +HY ++   +++++ LY
Sbjct: 65  HLVPIAKQEGFKYDLDQLANLVSLCPHCHRLIHYGQDEEKEKMLKKLY 112


>UniRef50_C8U495 Endonuclease-like protein n=2 Tax=Escherichia coli
           RepID=C8U495_ECO10
          Length = 246

 Score = 47.8 bits (112), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 5/81 (6%)

Query: 181 EVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSS---- 235
           ++ERL   Y RDP  +   +      C  CG N    Y + G  Y++VHH+ PL      
Sbjct: 144 QLERLATYYERDPKARQACIDAHGYTCHICGFNFEKVYGSIGKNYIQVHHIKPLHHIAKY 203

Query: 236 GGADTTDNCVALCPNCHRELH 256
              D  ++ + LC NCH  +H
Sbjct: 204 HKVDPVNDLIPLCANCHVMIH 224


>UniRef50_C7V3C1 Predicted protein n=1 Tax=Enterococcus faecalis T11
           RepID=C7V3C1_ENTFA
          Length = 288

 Score = 47.4 bits (111), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 21/46 (45%), Positives = 26/46 (56%), Gaps = 5/46 (10%)

Query: 224 YLEVHHVIPLSS-----GGADTTDNCVALCPNCHRELHYSKNAKEL 264
           Y+E HH+IPLS+        D T N   LCP CHR +HY K   +L
Sbjct: 212 YMETHHIIPLSAQRYYKNKLDCTANLSCLCPTCHRSIHYGKKEDKL 257


>UniRef50_Q5YRW6 Putative endonuclease n=1 Tax=Nocardia farcinica RepID=Q5YRW6_NOCFA
          Length = 123

 Score = 47.0 bits (110), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 27/76 (35%), Positives = 40/76 (52%), Gaps = 6/76 (7%)

Query: 202 QSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSSGGADTT--DNCVALCPNCHRELHYS 258
            S+  CE CG +    Y   G  Y+E HH++PL   G   T   + V LC NCHR +H+ 
Sbjct: 34  HSRVFCEVCGFDFEAVYGERGAGYIECHHIVPLHVSGETVTKLSDLVLLCSNCHRMIHHG 93

Query: 259 K---NAKELIEMLYVN 271
               + +EL E++ V+
Sbjct: 94  SRWLSPEELREVVQVS 109


>UniRef50_C6MKA5 HNH endonuclease n=1 Tax=Geobacter sp. M18 RepID=C6MKA5_9DELT
          Length = 254

 Score = 47.0 bits (110), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 26/79 (32%), Positives = 41/79 (51%), Gaps = 5/79 (6%)

Query: 187 KVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSS----GGADTT 241
           K Y R+P+ +   ++    +C  CG N    Y   G+ Y+EVHHV P+S+       D  
Sbjct: 160 KRYERNPVNRLEAIRYHGLVCNVCGFNFEEVYGERGSGYIEVHHVEPISTYDGEQPVDPK 219

Query: 242 DNCVALCPNCHRELHYSKN 260
            + + +C NCHR +H + N
Sbjct: 220 TDLITVCSNCHRMIHRNPN 238


>UniRef50_A0ZAT3 Putative uncharacterized protein n=1 Tax=Nodularia spumigena
           CCY9414 RepID=A0ZAT3_NODSP
          Length = 394

 Score = 47.0 bits (110), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 5/56 (8%)

Query: 206 ICENCGKNAPFYLNDGNPYLEVHHVIPLSS-----GGADTTDNCVALCPNCHRELH 256
           +C+ C  N        +  LE+HH++PLSS     G   + ++ V LCPNCHR +H
Sbjct: 305 VCDMCSCNTRHRYPWTDNLLEIHHLLPLSSAITVTGEGTSLEDVVGLCPNCHRSVH 360


>UniRef50_C9RBS6 HNH endonuclease n=4 Tax=Ammonifex degensii KC4 RepID=C9RBS6_AMMDK
          Length = 388

 Score = 47.0 bits (110), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 22/52 (42%), Positives = 27/52 (51%), Gaps = 9/52 (17%)

Query: 205 GICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELH 256
           G C  CG             L+ HH++P S GG DT +N V LC  CHR+LH
Sbjct: 185 GACVLCGSTR---------RLQRHHLVPRSKGGTDTPENQVLLCAECHRKLH 227


>UniRef50_Q0HF94 Putative uncharacterized protein n=1 Tax=Shewanella sp. MR-4
           RepID=Q0HF94_SHESM
          Length = 295

 Score = 46.6 bits (109), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 23/65 (35%), Positives = 36/65 (55%), Gaps = 8/65 (12%)

Query: 221 GNPYLEVHHVIPLSSG-----GADTTDNCVALCPNCHRELHYSKNAK--ELIEMLY-VNI 272
           G  ++E HH++P++         D   N V LCPNCHR +HY+++    EL+   Y   I
Sbjct: 215 GKAFVEAHHLVPVAKSPDFDVSLDVEPNIVVLCPNCHRAIHYAESQYKIELLTRFYNQRI 274

Query: 273 NRLQK 277
           N L++
Sbjct: 275 NELRQ 279


>UniRef50_Q538B5 MnlI restriction endonuclease n=2 Tax=Moraxella nonliquefaciens
           RepID=Q538B5_MORNO
          Length = 386

 Score = 46.6 bits (109), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 27/55 (49%), Positives = 31/55 (56%), Gaps = 9/55 (16%)

Query: 224 YLEVHHVIPLSSGGA-DTTDNCVALCPNCHRELHYSKN------AKELIEMLYVN 271
           YLEVHHVI  +S    D  DN V +CP CHR L  SKN       KELI  + +N
Sbjct: 308 YLEVHHVISFASDRTLDQIDNLVKVCPTCHRAL--SKNRADEQYQKELISEILIN 360


>UniRef50_C2ECC9 Recombinase n=1 Tax=Lactobacillus ruminis ATCC 25644
           RepID=C2ECC9_9LACO
          Length = 270

 Score = 46.2 bits (108), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 38/145 (26%), Positives = 63/145 (43%), Gaps = 11/145 (7%)

Query: 135 SFWASIIRGELSELSQ-PTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDP 193
           +F+++ I G L  L Q    +   +    S+  K  L +    + PV+   LQ  Y R+P
Sbjct: 105 NFYSATINGYLDYLDQLKIVNAGEIKESPSERYKIKLLKKPVRKSPVQTTILQ--YPRNP 162

Query: 194 MVKAWILQQSKGICENCGKNAPFYL-NDGNPYLEVHHVIPLSSG-----GADTTDNCVAL 247
                   +S   C     +  F   ND   ++E HH+IP+          D  DN + L
Sbjct: 163 HEMLAAKHRSGWKCCYDSSHETFISENDHKNFVEGHHLIPMQHQCDFEYTIDFADNIIPL 222

Query: 248 CPNCHRELHYS--KNAKELIEMLYV 270
           CP CHR +H++  ++   ++E  Y 
Sbjct: 223 CPTCHRRIHFAIKQDRNRMLEKFYF 247


>UniRef50_Q46AN8 Putative uncharacterized protein n=1 Tax=Methanosarcina barkeri
           str. Fusaro RepID=Q46AN8_METBF
          Length = 268

 Score = 46.2 bits (108), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 23/62 (37%), Positives = 33/62 (53%), Gaps = 3/62 (4%)

Query: 207 CENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTD--NCVALCPNCHRELHYSKNAKEL 264
           C  CG    F   +G  Y EVHH+I L+    +T    N + +CP CHR+LHY+    E 
Sbjct: 193 CMICGYPG-FLKKNGEKYAEVHHMIELNQKAPETLQSWNLLVVCPLCHRKLHYADVKSEF 251

Query: 265 IE 266
           ++
Sbjct: 252 LD 253


>UniRef50_A0L1U4 HNH endonuclease n=1 Tax=Shewanella sp. ANA-3 RepID=A0L1U4_SHESA
          Length = 224

 Score = 46.2 bits (108), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 32/99 (32%), Positives = 46/99 (46%), Gaps = 9/99 (9%)

Query: 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIP 232
           EGS K V V +    Y RD   +   +      C+ CG N +  Y   G  ++EVHH+ P
Sbjct: 123 EGSVKRVLVNK----YERDAKARKACIAHHGCQCKVCGFNFSETYGLHGEGFIEVHHITP 178

Query: 233 LS----SGGADTTDNCVALCPNCHRELHYSKNAKELIEM 267
           LS    S   D  ++ + +C NCH  LH  K    + E+
Sbjct: 179 LSTISKSYQVDPINDLIPVCSNCHSMLHRGKEPLSIDEL 217


>UniRef50_C3AFV2 Putative uncharacterized protein n=1 Tax=Bacillus mycoides DSM 2048
           RepID=C3AFV2_BACMY
          Length = 140

 Score = 46.2 bits (108), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 24/76 (31%), Positives = 36/76 (47%), Gaps = 10/76 (13%)

Query: 181 EVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADT 240
           E E+L++ + R+   + W   +   +CE C      +L         HH IPL +GG + 
Sbjct: 3   EYEQLRQKF-RNISKQYWKQTKKPKMCEKCFSKTDVHL---------HHKIPLKTGGTND 52

Query: 241 TDNCVALCPNCHRELH 256
            DN + LC  CH E H
Sbjct: 53  YDNLIPLCEECHWEFH 68


>UniRef50_C4L1L5 HNH endonuclease n=2 Tax=Bacillales RepID=C4L1L5_EXISA
          Length = 346

 Score = 46.2 bits (108), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 38/134 (28%), Positives = 58/134 (43%), Gaps = 12/134 (8%)

Query: 141 IRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWIL 200
           + GEL +      D+ L     +  + ++L   EG RK V V      Y R+P+ +   +
Sbjct: 204 LMGELKDYITSFFDKDLTAEYYADEVAESLE--EGKRKVVTV----NTYERNPLARKRCM 257

Query: 201 QQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSSGG----ADTTDNCVALCPNCHREL 255
           +     C+ C  N    Y   G  ++ VHH+ PL   G     D   +   +CPNCH  L
Sbjct: 258 EYYGVSCQVCQINFEKIYGEVGRDFIHVHHIKPLHEIGQNYVVDPITDLRPVCPNCHAML 317

Query: 256 HYSKNAKEL-IEML 268
           H  +  + L IE L
Sbjct: 318 HRKEGGEYLTIEQL 331


>UniRef50_Q8DK67 Reverse transcriptase n=1 Tax=Thermosynechococcus elongatus BP-1
           RepID=Q8DK67_THEEB
          Length = 317

 Score = 46.2 bits (108), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 31/58 (53%), Gaps = 5/58 (8%)

Query: 199 ILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELH 256
           + ++  GIC  CG        + +   E+HH++P   GG D  DN V +  NCH+++H
Sbjct: 250 LWKKQGGICPVCGGEI-----EQDMLTEIHHILPKHKGGTDDLDNLVLIHTNCHKQVH 302


>UniRef50_A3YQ82 MnlI restriction endonuclease n=1 Tax=Campylobacter jejuni subsp.
           jejuni 260.94 RepID=A3YQ82_CAMJE
          Length = 259

 Score = 46.2 bits (108), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 6/57 (10%)

Query: 205 GICENCGK-----NAPFYLNDGNPYLEVHHVIPLS-SGGADTTDNCVALCPNCHREL 255
            +C  C K     +  F + +G  YLE+HH I  + S   D  DN V LCP CHR L
Sbjct: 154 DLCAACNKTYNIDDRSFKMKNGFYYLELHHNIAFAYSNECDELDNLVKLCPTCHRAL 210


>UniRef50_Q8TKB6 Hnh endonuclease n=2 Tax=Methanosarcina RepID=Q8TKB6_METAC
          Length = 279

 Score = 45.8 bits (107), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 34/110 (30%), Positives = 50/110 (45%), Gaps = 13/110 (11%)

Query: 171 SQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHH 229
           S PEG +      R    Y R+   +   +     +C+ CG +    Y   G  Y+EVHH
Sbjct: 172 STPEGKKILCYTTR----YERNAQNRRNAIAIHGTVCQGCGFDFEKTYGEIGRDYIEVHH 227

Query: 230 VIPL----SSGGADTTDNCVALCPNCHRELHYSKNA----KELIEMLYVN 271
           V PL     S   +   + + +C NCHR +H  K++    KEL E+L  N
Sbjct: 228 VKPLCEEEGSVPINAETDLICVCANCHRMIHRRKDSVLSLKELQELLLAN 277


>UniRef50_C3RB64 Predicted protein n=1 Tax=Bacteroides dorei 5_1_36/D4
           RepID=C3RB64_9BACE
          Length = 274

 Score = 45.8 bits (107), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 33/109 (30%), Positives = 50/109 (45%), Gaps = 10/109 (9%)

Query: 158 LNMRVSKLIKKTLSQPEGSRKPVEVE-RLQKV----YVRDPMVKAWILQQSKGICENCGK 212
             +  S L    +S+ E  +K V+ E  +Q++    Y R+P+ +   L +    C  CG 
Sbjct: 148 FELIFSLLTITDISEEEFLQKAVQTEGTIQEIKSIRYERNPINRKLCLYKKGYTCAVCGM 207

Query: 213 N-APFYLNDGNPYLEVHHVIPLSSGGA----DTTDNCVALCPNCHRELH 256
           N    Y + G  ++EVHH  P+S  G     D   + V LC NCH   H
Sbjct: 208 NFQDVYGDIGKGFIEVHHTTPVSKMGEGYNLDIERDLVPLCSNCHSMTH 256


>UniRef50_D0IIJ2 HNH endonuclease n=1 Tax=Vibrio sp. RC586 RepID=D0IIJ2_9VIBR
          Length = 244

 Score = 45.4 bits (106), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 29/93 (31%), Positives = 43/93 (46%), Gaps = 9/93 (9%)

Query: 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLND-GNPYLEVHHVIP 232
           EG+RK + V      Y R+   +A  ++     C  C  N   Y  D G  Y+ VHH + 
Sbjct: 140 EGARKQITV----NAYERNHRARAQCIEHYGNSCYICSFNFFEYFGDLGAGYIHVHHQVD 195

Query: 233 LSSGG----ADTTDNCVALCPNCHRELHYSKNA 261
           L+  G     +  ++   +CPNCH  LH +K A
Sbjct: 196 LAHVGEAYIVNPIEDLKPVCPNCHAMLHKTKPA 228


>UniRef50_C6WXV3 HNH endonuclease n=3 Tax=Proteobacteria RepID=C6WXV3_METML
          Length = 238

 Score = 45.1 bits (105), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 26/77 (33%), Positives = 39/77 (50%), Gaps = 11/77 (14%)

Query: 191 RDPMVKAWILQQSKG----ICENCGKNAPFYLNDG---NPYLEVHHVIPLSSGGADTT-- 241
           R+P ++  +L   +      CE CG  AP + ++      + E HH+IPLS+ G   T  
Sbjct: 145 REPKLRGQLLSSRRVSGNLFCEMCG--APPHTSNAMLQEAHFEAHHIIPLSNTGVRKTRL 202

Query: 242 DNCVALCPNCHRELHYS 258
            +   LC NCHR LH +
Sbjct: 203 SDLALLCANCHRLLHRA 219


>UniRef50_D2QLF4 HNH endonuclease n=1 Tax=Spirosoma linguale DSM 74
           RepID=D2QLF4_9SPHI
          Length = 367

 Score = 45.1 bits (105), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 29/107 (27%), Positives = 47/107 (43%), Gaps = 9/107 (8%)

Query: 166 IKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPY 224
           +  T +  EG+ K + V R    Y RD   +   +      C+ C  +    Y N G  Y
Sbjct: 238 VPSTKTYVEGAVKQITVNR----YERDQDARTDCINHYGAKCQACEFDFEEIYGNIGKGY 293

Query: 225 LEVHHVIPL----SSGGADTTDNCVALCPNCHRELHYSKNAKELIEM 267
           + VHH+ P     +S   D   + + +CPNCH  LH  K   ++ ++
Sbjct: 294 IHVHHIKPFNEIKTSYRVDPIKDLIPVCPNCHAMLHTGKEVMDIADL 340


>UniRef50_Q6EME6 Hnh endonuclease n=6 Tax=Enterobacteriaceae RepID=Q6EME6_ECOLX
          Length = 302

 Score = 45.1 bits (105), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 25/90 (27%), Positives = 45/90 (50%), Gaps = 10/90 (11%)

Query: 189 YVRDPMVKAWILQQSKGICE-NCGKNAPFYLNDGNP--YLEVHHVIPLSS-----GGADT 240
           Y R   V    L ++   C+ NC  + P +    +P  Y E HH++P+S         D 
Sbjct: 188 YPRSKSVSKNALNKADYKCQINC--DHPTFRRRNSPLNYTEPHHIVPMSKQDYFENSLDV 245

Query: 241 TDNCVALCPNCHRELHYSKNAKELIEMLYV 270
            +N ++LC NCH+++H  K  ++++  +Y 
Sbjct: 246 EENIISLCCNCHKQIHLGKGFEDMLRKIYA 275


>UniRef50_A5V9C7 HNH endonuclease n=1 Tax=Sphingomonas wittichii RW1
           RepID=A5V9C7_SPHWW
          Length = 426

 Score = 45.1 bits (105), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 9/85 (10%)

Query: 181 EVERLQKVYVR----DPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSG 236
           E  ++QK +V       + KA+       +C+ C  +           +++HH++PLSSG
Sbjct: 304 EGNKVQKTHVTIERNSGLRKAFFAANPTTVCDVCNLDTARSYPWTERVMDLHHLLPLSSG 363

Query: 237 ----GADTT-DNCVALCPNCHRELH 256
               G  TT D+ V LCP+CHR +H
Sbjct: 364 TRVIGRGTTFDDLVPLCPSCHRAVH 388


>UniRef50_D2S2Y4 HNH endonuclease n=1 Tax=Haloterrigena turkmenica DSM 5511
           RepID=D2S2Y4_9EURY
          Length = 221

 Score = 45.1 bits (105), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 11/83 (13%)

Query: 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPL 233
            G+R P    R + VY  D              C++CG+ +  +  +    L  HH++PL
Sbjct: 19  SGNRPPDWEARRKTVYRHD-----------NWTCQSCGRQSGPHAGNEGVRLHAHHIVPL 67

Query: 234 SSGGADTTDNCVALCPNCHRELH 256
           S GG++   N   LC  CH+  H
Sbjct: 68  SEGGSNRLSNLETLCEPCHQNQH 90


>UniRef50_C3BJL8 Paclitaxel/taxanoid biosynthesis susceptibility protein TS1 n=1
           Tax=Bacillus pseudomycoides DSM 12442 RepID=C3BJL8_9BACI
          Length = 374

 Score = 45.1 bits (105), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 25/88 (28%), Positives = 38/88 (43%), Gaps = 14/88 (15%)

Query: 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254
            + ++  +    C+ C K            L  HH+I   SGG+D  DN V +   CH++
Sbjct: 141 TRYYVFTRDHYTCQICKKKGGI--------LHTHHIIERCSGGSDMADNLVTVHEECHQK 192

Query: 255 LHYS------KNAKELIEMLYVNINRLQ 276
            H        K  K+  E  ++NI RLQ
Sbjct: 193 FHQGTIKHIFKKPKQYKETAFMNILRLQ 220


>UniRef50_C4UQ38 Putative uncharacterized protein n=1 Tax=Yersinia rohdei ATCC 43380
           RepID=C4UQ38_YERRO
          Length = 206

 Score = 44.7 bits (104), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 49/177 (27%), Positives = 73/177 (41%), Gaps = 35/177 (19%)

Query: 111 GRKEIPSGNRTKRILINVPG-IYSDSF----------WASIIRGELSELSQPTDDESLLN 159
            R  I S     R++  + G  Y+DSF          + S +  ELS    P   + +LN
Sbjct: 41  NRTTISSNEEITRLISKMSGGYYADSFVSNCSTAMRRYLSFVNSELSYFHYP---DEILN 97

Query: 160 MRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYL 218
              S+ I       EG++K + V      Y RD   +   ++     C  C  N    Y 
Sbjct: 98  H--SEYI-------EGAKKQIIVNS----YERDRDARNKAIEIHGLNCSVCDMNFEDVYG 144

Query: 219 NDGNPYLEVHHVIPLSSGG----ADTTDNCVALCPNCHRELHYSKN---AKELIEML 268
             G  ++ VHH+ PL         D  D+ + +CPNCH  LH  KN    KEL +++
Sbjct: 145 EIGVGFIHVHHLKPLHEINKEYHVDPEDDLITVCPNCHAMLHRLKNRPSKKELKDLI 201


>UniRef50_D2RK49 HNH endonuclease n=11 Tax=Bacteria RepID=D2RK49_ACIFE
          Length = 128

 Score = 44.7 bits (104), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 32/95 (33%), Positives = 45/95 (47%), Gaps = 15/95 (15%)

Query: 164 KLIKKTLSQPEGSRKPVEVERLQKVY--VRDPMVKAWILQQSKGICENCGKNAPFYLNDG 221
           K+I K   + E  R P   +R  K +  +RD  V       S  +CE C KN  + + + 
Sbjct: 28  KIIAKRYEKYE--RSPATKKRYGKSWKKIRDAYV------SSHPLCELCLKNGRYVVAE- 78

Query: 222 NPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELH 256
               EVHH  PL+ GG    +N +ALC  CH  +H
Sbjct: 79  ----EVHHKKPLAEGGTHAWNNLIALCKACHARIH 109


>UniRef50_B7JSJ9 DNA helicase, putative n=1 Tax=Bacillus cereus AH820
           RepID=B7JSJ9_BACC0
          Length = 278

 Score = 44.7 bits (104), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 23/63 (36%), Positives = 32/63 (50%), Gaps = 7/63 (11%)

Query: 207 CENCGKNAPFYL--NDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKEL 264
           C+ CG    +    N     +EV H+I  S GG +T DN   LCPNCH     +K  + +
Sbjct: 196 CQVCGFKEEYIKANNKKGWIIEVDHIIEKSKGGGETFDNLWVLCPNCH-----AKKTRGI 250

Query: 265 IEM 267
           IE+
Sbjct: 251 IEI 253


>UniRef50_D2AT16 Putative uncharacterized protein n=1 Tax=Streptosporangium roseum
           DSM 43021 RepID=D2AT16_STRRD
          Length = 419

 Score = 44.7 bits (104), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 25/67 (37%), Positives = 33/67 (49%), Gaps = 4/67 (5%)

Query: 190 VRDPMVKAWILQQSKGICENCGKNAPFYLND----GNPYLEVHHVIPLSSGGADTTDNCV 245
            R    K  +L + KG CEN     P   +D    G P L+V H+   + GG D  +  +
Sbjct: 323 ARSTPAKRAVLLRCKGACENPDCENPGRPSDTSVGGGPILDVDHIDDHAKGGRDYPELMI 382

Query: 246 ALCPNCH 252
           ALCPNCH
Sbjct: 383 ALCPNCH 389


>UniRef50_C3G8U4 HNH endonuclease n=1 Tax=Bacillus thuringiensis serovar
           andalousiensis BGSC 4AW1 RepID=C3G8U4_BACTU
          Length = 258

 Score = 44.7 bits (104), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 38/116 (32%), Positives = 56/116 (48%), Gaps = 11/116 (9%)

Query: 166 IKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPY 224
           + + LS  EG+RK V V +    Y R  + +   ++     C  C  +    Y + G  +
Sbjct: 147 VPEQLSIMEGNRKTVVVNQ----YERSAVARRKCIEHHGCYCHVCHLDFKKQYGSLGKGF 202

Query: 225 LEVHHVIPLSSGG----ADTTDNCVALCPNCHRELHY-SKNAKEL-IEMLYVNINR 274
           + VHH IPLS  G     D  ++ + +CPNCH  LH  S N   L IE L V +N+
Sbjct: 203 IHVHHKIPLSEIGDEYEVDYVNDLIPVCPNCHAMLHRKSMNGSFLTIEELKVLMNK 258


>UniRef50_D2YH85 Putative uncharacterized protein n=1 Tax=Vibrio mimicus VM603
           RepID=D2YH85_VIBMI
          Length = 208

 Score = 44.7 bits (104), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 14/97 (14%)

Query: 189 YVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSS--GGADTTDNCVA 246
           ++RD  +   + +++   C+ C     F L +G PY E HH+ PL     G D   N + 
Sbjct: 106 FIRDSKLSQLVKKKNNYKCQICA--FTFLLPNGKPYAEAHHLKPLGKEHDGPDIEGNLIC 163

Query: 247 LCPNCHRELHYS----------KNAKELIEMLYVNIN 273
           +CPN H  L Y           KN+K  I   +++ N
Sbjct: 164 VCPNHHAMLDYCSLKLDVNAIVKNSKHEIMKEFIDYN 200


>UniRef50_B3Z1Y7 Gp45 n=1 Tax=Bacillus cereus W RepID=B3Z1Y7_BACCE
          Length = 375

 Score = 44.3 bits (103), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 11/79 (13%)

Query: 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPL 233
           +G  K  E  RL+K   R+   K ++L    G C  CG  A            + H+IP 
Sbjct: 108 DGLEKIREQNRLRKQKQREKE-KQYLLGNDMGTCAYCGDQAN----------TLDHLIPK 156

Query: 234 SSGGADTTDNCVALCPNCH 252
           S GG DT +NCV+ C  C+
Sbjct: 157 SHGGLDTQENCVSCCKQCN 175


>UniRef50_C2LK08 Putative uncharacterized protein n=1 Tax=Proteus mirabilis ATCC
           29906 RepID=C2LK08_PROMI
          Length = 98

 Score = 44.3 bits (103), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 22/48 (45%), Positives = 26/48 (54%), Gaps = 5/48 (10%)

Query: 207 CENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254
           C  CG    F   DG    E+ H+IPL  GG DT +NC  LC  CHR+
Sbjct: 48  CAACGSLLAF--PDG---FELDHIIPLFKGGKDTIENCQVLCIECHRK 90


>UniRef50_A9GYN9 Putative uncharacterized protein n=1 Tax=Roseobacter litoralis Och
           149 RepID=A9GYN9_9RHOB
          Length = 311

 Score = 43.9 bits (102), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 5/67 (7%)

Query: 206 ICENCGKN-APFYLNDGNPYLEVHHVIPLSSGGADTTD----NCVALCPNCHRELHYSKN 260
           IC  CG + A FY   G  ++ VHH+ P+S   A        + V +CPNCH  +H    
Sbjct: 240 ICIVCGFDFAAFYGTLGEGFIHVHHLNPISEAEASRIVSPEIDLVPVCPNCHSMIHRGGQ 299

Query: 261 AKELIEM 267
            + + EM
Sbjct: 300 TRSIAEM 306


>UniRef50_A4G659 Putative restriction endonuclease n=1 Tax=Herminiimonas
           arsenicoxydans RepID=A4G659_HERAR
          Length = 269

 Score = 43.9 bits (102), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 21/53 (39%), Positives = 29/53 (54%), Gaps = 5/53 (9%)

Query: 207 CENCGKNAPFYLNDGNPYLEVHHVIPLSSGGAD---TTDNCVALCPNCHRELH 256
           C+ C KN  F    G  Y+E HH IP+SS  +     + +   LCPNCH+ +H
Sbjct: 194 CDVCQKN--FEKEYGVKYIEAHHKIPISSFSSKHPVKSSDFALLCPNCHKAIH 244


>UniRef50_Q8SDH4 Putative uncharacterized protein n=1 Tax=Lactobacillus phage LL-H
           RepID=Q8SDH4_BPLLH
          Length = 112

 Score = 43.9 bits (102), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 15/84 (17%)

Query: 173 PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIP 232
           P+G R  +   + +++YVRD           KGIC  CGK+  F  N       + H+ P
Sbjct: 26  PKGQRPKISKAKRKRIYVRD-----------KGICAYCGKHLEFKPNG----FHIDHIKP 70

Query: 233 LSSGGADTTDNCVALCPNCHRELH 256
           L+ GG +   N    C  C+   H
Sbjct: 71  LAKGGNNEDSNLTVSCRECNLSKH 94


>UniRef50_A1F1U9 HNH endonuclease domain protein n=1 Tax=Vibrio cholerae 2740-80
           RepID=A1F1U9_VIBCH
          Length = 210

 Score = 43.9 bits (102), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 20/134 (14%)

Query: 137 WASIIRGELSELSQPTD---DESLLNMRVSKL-------------IKKTLSQPEGSRKPV 180
           W ++IR  + +LS  +D   +   L   V+ L               K    P G+++P 
Sbjct: 39  WKAVIRRRIQDLSSDSDGFKNGQDLFYSVNGLGGGMWGLRNKLAYTPKAADLPTGTKEPE 98

Query: 181 EVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSS--GGA 238
                    +RD  +   +       C+ CG      L +G  Y E HH+IPL +   G+
Sbjct: 99  REYTTTYRVLRDTNLARKLKLLYNNSCQICG--LQIQLPNGKLYSEAHHIIPLGNPHHGS 156

Query: 239 DTTDNCVALCPNCH 252
           DT +N + LCPN H
Sbjct: 157 DTPENIIVLCPNHH 170


>UniRef50_A5N0L8 Phage-related protein n=15 Tax=Bacteria RepID=A5N0L8_CLOK5
          Length = 119

 Score = 43.9 bits (102), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 27/82 (32%), Positives = 38/82 (46%), Gaps = 16/82 (19%)

Query: 181 EVERLQKVYVRDPMVK-----AWILQQSKGI-----CENCGKNAPFYLNDGNPYLEVHHV 230
           E  R +K Y RDP  +     AW   + + I     CE C +          P  EVHH+
Sbjct: 30  EAARYEK-YDRDPATRKRYGRAWKRIRDRYIAAHPLCEECKRQGKL-----TPATEVHHI 83

Query: 231 IPLSSGGADTTDNCVALCPNCH 252
           +PL+ GG     N ++LC +CH
Sbjct: 84  LPLARGGTHDRSNLMSLCTSCH 105


>UniRef50_B4SDY4 HNH nuclease n=4 Tax=Bacteria RepID=B4SDY4_PELPB
          Length = 309

 Score = 43.9 bits (102), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 19/58 (32%), Positives = 29/58 (50%)

Query: 199 ILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELH 256
           +LQ+    C+ CG +   +      +LE HH+     GG +T +N V LC  CH + H
Sbjct: 250 VLQRDDYRCQQCGWHQEMWNQSDPRHLEAHHIKQHVEGGENTKENLVTLCNICHDKEH 307


>UniRef50_B9JB56 Putative uncharacterized protein n=1 Tax=Agrobacterium radiobacter
           K84 RepID=B9JB56_AGRRK
          Length = 219

 Score = 43.9 bits (102), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 34/89 (38%), Positives = 44/89 (49%), Gaps = 10/89 (11%)

Query: 171 SQPEGS--RKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVH 228
           S+ EG+   K V   R+ +  V    VKA  L  SK  C+ CG +    L DG  Y E H
Sbjct: 97  SEIEGAVLAKEVTTNRIIRDTVMTCKVKA--LHHSK--CQICGTS--ISLPDGRAYSEAH 150

Query: 229 HVIPLSSG--GADTTDNCVALCPNCHREL 255
           H+IPL +   G D   N + +CPN H  L
Sbjct: 151 HIIPLGAPHRGPDIPSNIIIVCPNHHAML 179


>UniRef50_Q1YWU8 Putative uncharacterized protein n=3 Tax=Gammaproteobacteria
           RepID=Q1YWU8_PHOPR
          Length = 244

 Score = 43.9 bits (102), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 33/102 (32%), Positives = 50/102 (49%), Gaps = 9/102 (8%)

Query: 171 SQPEGSRKPVEVERLQK-VYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHH 229
           S PEG  K V +   ++    R+  ++ + L  S  +CE   + A  Y   G  ++ VHH
Sbjct: 138 SFPEGMAKKVVINSFERNKTARNSCIEEYGLSCS--VCEFNFEKA--YGELGTGFIHVHH 193

Query: 230 VIPLSSGG----ADTTDNCVALCPNCHRELHYSKNAKELIEM 267
           V+ +SS G     D   + V +CPNCH  LH  K A  + E+
Sbjct: 194 VVDISSIGYAYQVDPKKDLVPVCPNCHAMLHKRKPAFTVQEL 235


>UniRef50_D1XF45 HNH endonuclease n=3 Tax=Streptomyces RepID=D1XF45_9ACTO
          Length = 354

 Score = 43.5 bits (101), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 24/64 (37%), Positives = 34/64 (53%), Gaps = 4/64 (6%)

Query: 197 AWILQQSKGI-CENCGKN-APFYLNDGNPYLEVHHVIPLSSGGADTTD--NCVALCPNCH 252
           A +LQ+   + CE CG +    Y + G  Y+E HHV+PL   G   T   +   +C NCH
Sbjct: 248 ASVLQRGGQLACEACGFDFEKIYGDRGAGYIECHHVLPLHVAGEGRTKLGDLALICANCH 307

Query: 253 RELH 256
           R +H
Sbjct: 308 RMIH 311


>UniRef50_A1REN7 HNH nuclease n=1 Tax=Shewanella sp. W3-18-1 RepID=A1REN7_SHESW
          Length = 387

 Score = 43.5 bits (101), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 24/90 (26%), Positives = 41/90 (45%), Gaps = 12/90 (13%)

Query: 183 ERLQKVYVRDPMVKAWILQQSKGICENC---GKNAPFYLNDGNPYLEVHHVIPLSSGGAD 239
           ++L K  +    ++A ++ +    C  C   G+  P         LE+  + P + GG+ 
Sbjct: 4   QKLNKRRIPSVAMRAKLIAKHNNQCAMCTISGEEIP---------LELASITPFNEGGSM 54

Query: 240 TTDNCVALCPNCHRELHYSKNAKELIEMLY 269
           T +N + LCPNCHR +       E +  LY
Sbjct: 55  TEENFLLLCPNCHRYMTMGPKEIEFVNFLY 84


>UniRef50_B4D4V1 HNH endonuclease n=1 Tax=Chthoniobacter flavus Ellin428
           RepID=B4D4V1_9BACT
          Length = 212

 Score = 43.5 bits (101), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 31/101 (30%), Positives = 50/101 (49%), Gaps = 8/101 (7%)

Query: 160 MRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLN 219
           +R        +SQP  S+    ++R+ ++ +RD  + + +      IC+ CG      + 
Sbjct: 80  VRCDARAANDISQP--SQPDRVLQRISRI-IRDTAISSELKLLYDHICQLCGTQ--LVVC 134

Query: 220 DGNPYLEVHHVIPLS--SGGADTTDNCVALCPNCHRELHYS 258
           D   Y E HH+ PL     G+DT DN + +CPNCH  L Y+
Sbjct: 135 D-RLYSEAHHIRPLGRPHDGSDTRDNLLCVCPNCHVLLDYA 174


>UniRef50_A6FSB3 HNH nuclease n=2 Tax=Roseobacter sp. AzwK-3b RepID=A6FSB3_9RHOB
          Length = 115

 Score = 43.5 bits (101), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 23/57 (40%), Positives = 32/57 (56%), Gaps = 7/57 (12%)

Query: 196 KAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252
           +AW  ++++G CE CG      LN G+   E  H IP   GG ++ +NCV LC  CH
Sbjct: 13  QAW--ERARGKCEECG----VKLNVGD-RREFDHRIPCGLGGDNSLENCVVLCAACH 62


>UniRef50_B0VJM1 Putative ATP dependant helicase yprA n=1 Tax=Candidatus Cloacamonas
           acidaminovorans RepID=B0VJM1_9BACT
          Length = 863

 Score = 43.5 bits (101), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 22/51 (43%), Positives = 24/51 (47%), Gaps = 13/51 (25%)

Query: 207 CENCGKNAPFYLNDGNPYLEVHHVIPL----SSGGADTTDNCVALCPNCHR 253
           C NCG             LEVHH+IP         A+  DN VALCP CHR
Sbjct: 698 CRNCGATGD---------LEVHHIIPFRRFEDPAEANEPDNLVALCPRCHR 739


>UniRef50_B0MB23 Putative uncharacterized protein n=1 Tax=Anaerostipes caccae DSM
           14662 RepID=B0MB23_9FIRM
          Length = 99

 Score = 43.5 bits (101), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 17/34 (50%), Positives = 23/34 (67%)

Query: 223 PYLEVHHVIPLSSGGADTTDNCVALCPNCHRELH 256
           P  EVHH +PLS GG    DN ++LC +CH ++H
Sbjct: 47  PVDEVHHKLPLSEGGNHNKDNLISLCKSCHAKIH 80


>UniRef50_Q9R669 Group II SELF-splicing intron ORF (Fragments) n=1 Tax=Azotobacter
           vinelandii RepID=Q9R669_AZOVI
          Length = 86

 Score = 43.5 bits (101), Expect = 0.008,   Method: Composition-based stats.
 Identities = 17/30 (56%), Positives = 20/30 (66%)

Query: 227 VHHVIPLSSGGADTTDNCVALCPNCHRELH 256
           +HH+I    GG D  DN V L PNCHR+LH
Sbjct: 57  IHHIIKRHMGGGDELDNLVLLHPNCHRQLH 86


>UniRef50_C4XM37 Putative uncharacterized protein n=1 Tax=Desulfovibrio magneticus
           RS-1 RepID=C4XM37_DESMR
          Length = 251

 Score = 43.1 bits (100), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 12/84 (14%)

Query: 185 LQKVYVRDPMVKAWILQQSKGI--------CENCGKNA-PFYLNDGNPYLEVHHVIPLSS 235
           L K++V+    K+ I  + K +        CE CG +   FY   G  + EVHH+ PLS 
Sbjct: 150 LTKIHVQRERSKSLIESKKKYVMNTCGVLECEVCGFSFHKFYGERGKNFAEVHHIKPLSY 209

Query: 236 GGADTT---DNCVALCPNCHRELH 256
             A+ +   ++   +C NCHR +H
Sbjct: 210 LDAEASTKIEDLAIVCSNCHRMIH 233


>UniRef50_B0MFF1 Putative uncharacterized protein n=1 Tax=Anaerostipes caccae DSM
           14662 RepID=B0MFF1_9FIRM
          Length = 179

 Score = 43.1 bits (100), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 18/40 (45%), Positives = 25/40 (62%), Gaps = 1/40 (2%)

Query: 223 PYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAK 262
           P++EVHH+IP + G  DT +N   LC  CH +L+    AK
Sbjct: 25  PFVEVHHIIPQNEGDEDTIENAAPLCSRCH-DLYVDNPAK 63


>UniRef50_B2IX42 HNH endonuclease n=18 Tax=Cyanobacteria RepID=B2IX42_NOSP7
          Length = 95

 Score = 43.1 bits (100), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 18/62 (29%), Positives = 33/62 (53%), Gaps = 6/62 (9%)

Query: 193 PMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252
           P VK ++ ++ K  C++CGK           ++ + H+IPL+ GG +   N   LC  C+
Sbjct: 25  PEVKKYVFERDKYQCQSCGKTT------TETHISIDHIIPLARGGQNDISNLQTLCLTCN 78

Query: 253 RE 254
           ++
Sbjct: 79  QQ 80


>UniRef50_B8I0D2 HNH endonuclease n=1 Tax=Clostridium cellulolyticum H10
           RepID=B8I0D2_CLOCE
          Length = 177

 Score = 43.1 bits (100), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 43/166 (25%), Positives = 68/166 (40%), Gaps = 35/166 (21%)

Query: 109 RTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNM---RVSKL 165
           + G K +P  N+ KR            +W S+     +   Q  +D  L  M   R  K 
Sbjct: 7   KEGEKNLPYNNKGKR------------YWLSL----WNYAKQYPNDNILYQMPDYRADKN 50

Query: 166 IKKTLSQPEGSRK---------PVEVERLQKVYVRDPMVKAW-ILQQSKGICENCGKNAP 215
             K   Q   S++          +E +RL  V+ R      + IL +    C+ CG  A 
Sbjct: 51  TCKWCGQSLKSKRQQSYCCEDCKIEFQRL-AVWGRGVAPLPYRILCRDNFTCKECGLFAA 109

Query: 216 FYLNDG-----NPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELH 256
           +    G        L+VHH+I +S GG D  +N + +C +CH ++H
Sbjct: 110 YKNKHGLFVPIAVGLDVHHLIQVSEGGTDQQNNLITICNDCHNQIH 155


>UniRef50_Q2FQI6 HNH endonuclease n=1 Tax=Methanospirillum hungatei JF-1
           RepID=Q2FQI6_METHJ
          Length = 163

 Score = 43.1 bits (100), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 22/70 (31%), Positives = 36/70 (51%), Gaps = 9/70 (12%)

Query: 194 MVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHR 253
           +++  IL++    C+ CG+            L VHH+IPLS GG  T  N   LC +CH+
Sbjct: 61  VIRRQILERDGYRCQICGEQRD---------LSVHHIIPLSEGGDSTASNLRVLCHSCHQ 111

Query: 254 ELHYSKNAKE 263
           + H  +  ++
Sbjct: 112 QAHGKRAVRD 121


>UniRef50_A7I926 HNH endonuclease n=1 Tax=Candidatus Methanoregula boonei 6A8
           RepID=A7I926_METB6
          Length = 266

 Score = 43.1 bits (100), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 33/118 (27%), Positives = 58/118 (49%), Gaps = 18/118 (15%)

Query: 155 ESLLNMRVSKLIKKTLSQ-------PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGIC 207
           ES  ++   ++ K+TL++       PE   +  E E +Q +Y R+  ++   ++     C
Sbjct: 134 ESEWDILSKEIEKRTLTKYEEIFTCPEYFTEGKEREIIQTIYERNSKLREMAIKMHGTTC 193

Query: 208 ENCGKN-APFY--LNDGNPYLEVHHVIPLSS------GGADTTDNCVALCPNCHRELH 256
             CG N A  Y  L++G  Y+E+HH++P S          +   + + LC NCHR +H
Sbjct: 194 SVCGFNFAKKYGILSEG--YIEIHHLVPHSEHKIKGESEINPETDLIPLCSNCHRIIH 249


>UniRef50_C4F8E8 Putative uncharacterized protein n=1 Tax=Collinsella intestinalis
           DSM 13280 RepID=C4F8E8_9ACTN
          Length = 154

 Score = 42.7 bits (99), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 8/81 (9%)

Query: 174 EGSRKPVEVERLQKVYVRD--PMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVI 231
           +G +KP+   R      +   P ++  +L++    C+ CG  AP      +  L V H++
Sbjct: 62  DGKKKPMRARRSSGAERKPLPPRIRYEVLERDGYTCQYCGAKAP------SVTLHVDHIV 115

Query: 232 PLSSGGADTTDNCVALCPNCH 252
           P++ GG D   N VA C  C+
Sbjct: 116 PVAEGGTDDLSNLVAACEYCN 136


>UniRef50_UPI0001BC7B91 HNH endonuclease n=1 Tax=Bacteroides sp. D2 RepID=UPI0001BC7B91
          Length = 235

 Score = 42.7 bits (99), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 24/79 (30%), Positives = 36/79 (45%), Gaps = 5/79 (6%)

Query: 191 RDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSSGGA----DTTDNCV 245
           R+  ++   L+     C+ CG N    Y   G  Y+EVHH+ P++        D     +
Sbjct: 145 RNQALRQLCLKHYGYTCQVCGMNFEAVYGKLGKNYIEVHHINPIAETDGEHVLDPKTGLI 204

Query: 246 ALCPNCHRELHYSKNAKEL 264
            LC NCH  +H  KN + L
Sbjct: 205 PLCSNCHSMIHRGKNGRVL 223


>UniRef50_Q82CY5 Putative uncharacterized protein n=1 Tax=Streptomyces avermitilis
           RepID=Q82CY5_STRAW
          Length = 177

 Score = 42.7 bits (99), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 28/74 (37%), Positives = 35/74 (47%), Gaps = 5/74 (6%)

Query: 184 RLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSG--GADTT 241
           R+Q++ VRD  V   +     G C+ CG        DG PY E  H+ PL     G D  
Sbjct: 50  RIQRL-VRDAAVSRNVKDLYGGECQACGLR--LVGPDGRPYSEGAHIRPLGKPHCGPDVE 106

Query: 242 DNCVALCPNCHREL 255
            N + LCPNCH  L
Sbjct: 107 PNVLCLCPNCHVRL 120


>UniRef50_A9B2D5 HNH endonuclease n=1 Tax=Herpetosiphon aurantiacus ATCC 23779
           RepID=A9B2D5_HERA2
          Length = 321

 Score = 42.7 bits (99), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 9/58 (15%)

Query: 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252
           VK  + Q+ +G C  CG  +         YLE  H+IP S GGA+T  N   LC  C+
Sbjct: 266 VKLAVWQRDQGKCTQCGDAS---------YLEFDHIIPHSKGGANTVGNVQLLCRKCN 314


>UniRef50_B9MNG3 HNH endonuclease n=1 Tax=Anaerocellum thermophilum DSM 6725
           RepID=B9MNG3_ANATD
          Length = 443

 Score = 42.7 bits (99), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 31/83 (37%), Positives = 39/83 (46%), Gaps = 12/83 (14%)

Query: 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254
           VK ++L++    C  CG         G P LEV HVIP S GG D  DN V  C  C+++
Sbjct: 183 VKEYLLEKFNWRCVYCGAT-------GVP-LEVEHVIPKSRGGTDRVDNLVIACHGCNQK 234

Query: 255 LHYSKNAKELIEMLYVNINRLQK 277
               K  K   E  Y  I +L K
Sbjct: 235 ----KGNKTAEEFGYPEIQKLVK 253


>UniRef50_B7GM48 Restriction endonuclease, McrA/HNH family, phage related n=7
           Tax=Bacillaceae RepID=B7GM48_ANOFW
          Length = 92

 Score = 42.7 bits (99), Expect = 0.015,   Method: Composition-based stats.
 Identities = 26/73 (35%), Positives = 36/73 (49%), Gaps = 13/73 (17%)

Query: 204 KGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKE 263
           KG+CE CG+         +  L VHH+ P   GG +T      LC  CH+++H     +E
Sbjct: 2   KGMCELCGRE--------DVVLTVHHLTPKEYGGTETAK----LCIPCHKQIHALYTNEE 49

Query: 264 LIEMLYVNINRLQ 276
           L   LY  I +LQ
Sbjct: 50  LASRLY-TIEQLQ 61


>UniRef50_C3L8D2 Putative uncharacterized protein n=6 Tax=Bacillus anthracis
           RepID=C3L8D2_BACAC
          Length = 211

 Score = 42.7 bits (99), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 30/89 (33%), Positives = 41/89 (46%), Gaps = 9/89 (10%)

Query: 177 RKPVEVERLQKVYVRDPMVKAWILQQSKG--ICENCGKN-APFYLNDGNPYLEVHHVIPL 233
           R  +  ER  KV  R    K    Q+  G   CE CG +    Y   G  ++E HH IP+
Sbjct: 112 RTHLSYERNNKVIKR---AKEHFKQKHGGKIFCEICGFDFHKIYGELGKDFIEGHHTIPV 168

Query: 234 SS---GGADTTDNCVALCPNCHRELHYSK 259
           S    G     ++ + +C NCHR LH +K
Sbjct: 169 SQLKEGEKTRIEDIIMVCSNCHRMLHRTK 197


>UniRef50_C4K5N9 Group II intron encoded reverse transcriptase n=10 Tax=Candidatus
           Hamiltonella defensa 5AT (Acyrthosiphon pisum)
           RepID=C4K5N9_HAMD5
          Length = 570

 Score = 42.4 bits (98), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 23/65 (35%), Positives = 31/65 (47%), Gaps = 5/65 (7%)

Query: 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254
           VK  + ++ KG C  C +       D    L VHH+ P + GG +   N   L  NCHR+
Sbjct: 496 VKVNLYKRQKGYCPLCDQEL-----DNGEQLHVHHIQPKAEGGDNKLANLRLLHANCHRQ 550

Query: 255 LHYSK 259
           LH  K
Sbjct: 551 LHSKK 555


>UniRef50_B4SCA5 HNH nuclease n=1 Tax=Pelodictyon phaeoclathratiforme BU-1
           RepID=B4SCA5_PELPB
          Length = 340

 Score = 42.4 bits (98), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 33/118 (27%), Positives = 49/118 (41%), Gaps = 6/118 (5%)

Query: 142 RGELSELSQ-PTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERL---QKVYVRDPMVKA 197
           + EL   SQ   + E L        IK+ +     + +P + E +   +K Y RD    A
Sbjct: 193 KFELPYCSQDEKEQEELAQFYKQAKIKEEILDELNNLQPSDSEEIIVNKKTYKRDNKTIA 252

Query: 198 WILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHREL 255
            I       C+ CG        D + Y+E  H+      G +T DN + LCPN H+E 
Sbjct: 253 QIKILRDFKCQICG--VTITKKDRSKYIEAAHIKAKHQKGRETIDNIILLCPNHHKEF 308


>UniRef50_A9VH89 HNH endonuclease n=3 Tax=Bacillus cereus group RepID=A9VH89_BACWK
          Length = 276

 Score = 42.4 bits (98), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 2/48 (4%)

Query: 207 CENCGKNAPFYL--NDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252
           C+ CG    +    N     +EV H+I  S GG ++ DN   LCPNCH
Sbjct: 196 CQVCGFKEEYIKANNKKGWIIEVDHIIEKSKGGGESFDNLWVLCPNCH 243


>UniRef50_Q4C417 HNH endonuclease n=3 Tax=Crocosphaera watsonii WH 8501
           RepID=Q4C417_CROWT
          Length = 104

 Score = 42.4 bits (98), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 25/68 (36%), Positives = 37/68 (54%), Gaps = 5/68 (7%)

Query: 185 LQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNC 244
           ++  Y   P   + +L++ KGIC  C ++  F   D    +EV H+IP S GG DT +N 
Sbjct: 11  IRGAYTGTPNRVSKLLKKQKGICPQCKQH--FTPED---LIEVDHIIPKSKGGKDTYNNL 65

Query: 245 VALCPNCH 252
            AL  +CH
Sbjct: 66  QALHRHCH 73


>UniRef50_Q21AN9 HNH endonuclease n=1 Tax=Rhodopseudomonas palustris BisB18
           RepID=Q21AN9_RHOPB
          Length = 200

 Score = 42.4 bits (98), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 15/32 (46%), Positives = 22/32 (68%)

Query: 225 LEVHHVIPLSSGGADTTDNCVALCPNCHRELH 256
           L++HH+  +S+GG D + N +ALCP CH   H
Sbjct: 39  LDMHHIWEVSAGGTDDSSNLIALCPTCHALYH 70


>UniRef50_D2MHK7 HNH endonuclease n=3 Tax=Bacteria RepID=D2MHK7_9BACT
          Length = 171

 Score = 42.4 bits (98), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 6/61 (9%)

Query: 193 PMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252
           P ++A   ++ +GIC  CG++  F L      +E  H+ P S GG    +NC  LC  C+
Sbjct: 112 PTMRAAAYERQEGICPRCGEH--FVLG----AMEADHIDPWSEGGKTAPENCQMLCRPCN 165

Query: 253 R 253
           R
Sbjct: 166 R 166


>UniRef50_Q67M53 Conserved domain protein n=1 Tax=Symbiobacterium thermophilum
           RepID=Q67M53_SYMTH
          Length = 270

 Score = 42.0 bits (97), Expect = 0.020,   Method: Compositional matrix adjust.
 Identities = 29/81 (35%), Positives = 39/81 (48%), Gaps = 6/81 (7%)

Query: 182 VERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSS--GGA 238
           VE   + Y RDP  +   ++     C  CG N    Y   G  ++EVHHV PL +  G A
Sbjct: 159 VEYYGRRYERDPENRRRAIEIHGLNCVVCGFNFEEVYGPRGRDFIEVHHVKPLKAFEGVA 218

Query: 239 DTTD---NCVALCPNCHRELH 256
              D   + V +C NCHR +H
Sbjct: 219 QVVDPKVDLVPICANCHRMIH 239


>UniRef50_C3X695 Predicted protein n=1 Tax=Oxalobacter formigenes HOxBLS
           RepID=C3X695_OXAFO
          Length = 276

 Score = 42.0 bits (97), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 23/63 (36%), Positives = 35/63 (55%), Gaps = 5/63 (7%)

Query: 203 SKGICEN----CGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHREL-HY 257
           SK I E+    CG++           +E+HH+ P   GG D+ +NC+ LC +CH E+ HY
Sbjct: 4   SKEIVEDALVACGRSCCICHKFCGVRIEMHHLKPKHLGGDDSFENCIPLCFDCHAEVEHY 63

Query: 258 SKN 260
           + N
Sbjct: 64  NNN 66


>UniRef50_A1ZG09 Paclitaxel/taxanoid biosynthesis susceptibility protein TS1 n=5
           Tax=root RepID=A1ZG09_9SPHI
          Length = 453

 Score = 42.0 bits (97), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 19/65 (29%), Positives = 33/65 (50%), Gaps = 4/65 (6%)

Query: 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254
           ++ ++L + K  C+N      +        L+VHH++  S GG DT +N + LC  CH  
Sbjct: 180 IREYVLHRDKHSCQNPDCKNKY----KGKILQVHHIVFKSMGGGDTPNNLITLCTKCHTS 235

Query: 255 LHYSK 259
            ++ K
Sbjct: 236 ANHKK 240


>UniRef50_Q6LSI1 Putative uncharacterized protein MLL7993 n=1 Tax=Photobacterium
           profundum RepID=Q6LSI1_PHOPR
          Length = 207

 Score = 42.0 bits (97), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 34/100 (34%), Positives = 48/100 (48%), Gaps = 20/100 (20%)

Query: 171 SQPEGSRKPVEVERLQKVYVRD-------PMVKAWILQQSKGI-CENCGKN-APFYLNDG 221
           S PEG R    VER  K Y+R+          K + L+ +  + CE CG +    Y   G
Sbjct: 99  SFPEGKR----VER--KHYLRERSSALVEKAKKEYALKNNGRLPCEVCGFDFRECYGFHG 152

Query: 222 NPYLEVHHVIPLS-----SGGADTTDNCVALCPNCHRELH 256
           + Y+E HH++PLS      G     ++   +C NCHR LH
Sbjct: 153 DSYIEAHHIVPLSELCSADGTKTRLEDLAMVCSNCHRMLH 192


>UniRef50_A5UU02 HNH endonuclease n=16 Tax=Bacteria RepID=A5UU02_ROSS1
          Length = 197

 Score = 42.0 bits (97), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 23/66 (34%), Positives = 33/66 (50%), Gaps = 7/66 (10%)

Query: 190 VRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCP 249
           +R P  +  IL + +  C+ CG         G  +L V HV+P S GG  T +N V  C 
Sbjct: 96  MRLPCSRRSILLRDRETCQYCGAQ------PGRAHLTVDHVVPRSRGGETTWENVVTACR 149

Query: 250 NC-HRE 254
           +C HR+
Sbjct: 150 DCNHRK 155


>UniRef50_A9AZQ2 HNH endonuclease n=1 Tax=Herpetosiphon aurantiacus ATCC 23779
           RepID=A9AZQ2_HERA2
          Length = 271

 Score = 42.0 bits (97), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 36/153 (23%), Positives = 65/153 (42%), Gaps = 24/153 (15%)

Query: 122 KRILINVPGIYSDSFWASIIRGELSEL--SQPTDDESLLNMRVSKLIKKTLSQPEGSRKP 179
           K+ + NV  +  D  W++ I+  L +L  +QP                + ++ PE   + 
Sbjct: 130 KQSIQNVSTVEED--WSAAIQANLFDLPSTQP---------------HQPIASPEIFIEG 172

Query: 180 VEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSSGG- 237
            E + L   Y R+P  +   ++     C  C  + A  Y      ++ VHH+ PL++ G 
Sbjct: 173 AEYQSLVTRYERNPEARQRCIEHYGSTCVICHFDFAKVYGELAKGFIHVHHLKPLATIGE 232

Query: 238 ---ADTTDNCVALCPNCHRELHYSKNAKELIEM 267
               +  D+   +CPNCH  +H  K    + E+
Sbjct: 233 NYEVNPIDDLRPVCPNCHAVIHMRKEPYTIDEV 265


>UniRef50_Q477P3 HNH endonuclease n=1 Tax=Ralstonia eutropha JMP134
           RepID=Q477P3_RALEJ
          Length = 249

 Score = 41.6 bits (96), Expect = 0.026,   Method: Compositional matrix adjust.
 Identities = 34/107 (31%), Positives = 47/107 (43%), Gaps = 15/107 (14%)

Query: 154 DESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN 213
           DE L      +L+ +T    E SRK V+ +R Q           W  Q  K  CE C  +
Sbjct: 136 DEDLTEAPEGRLLTRTHLSRERSRKLVKAKREQ----------VWE-QTGKLRCEVCAFD 184

Query: 214 -APFYLNDGNPYLEVHHVIPLSSGGADTTD---NCVALCPNCHRELH 256
            A  Y   G  ++E HH  PLS+   ++     +   +C NCHR LH
Sbjct: 185 FAKAYGEHGAGFIECHHTKPLSTLPENSKTHIGDLALVCANCHRMLH 231


>UniRef50_C3AW04 Putative uncharacterized protein n=1 Tax=Bacillus mycoides Rock1-4
           RepID=C3AW04_BACMY
          Length = 212

 Score = 41.6 bits (96), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 25/65 (38%), Positives = 32/65 (49%), Gaps = 6/65 (9%)

Query: 201 QQSKG--ICENCGKNA-PFYLNDGNPYLEVHHVIPLSS---GGADTTDNCVALCPNCHRE 254
           QQ  G   CE CG +    Y   G  Y+E HH IP+S    G     ++ + +C NCHR 
Sbjct: 135 QQHGGKLFCEICGFDFYKTYGELGKDYIEGHHTIPVSQLKEGEKTKIEDIIMVCSNCHRM 194

Query: 255 LHYSK 259
           LH  K
Sbjct: 195 LHRRK 199


>UniRef50_B0KIU7 HNH endonuclease n=1 Tax=Pseudomonas putida GB-1 RepID=B0KIU7_PSEPG
          Length = 281

 Score = 41.6 bits (96), Expect = 0.031,   Method: Compositional matrix adjust.
 Identities = 30/100 (30%), Positives = 43/100 (43%), Gaps = 17/100 (17%)

Query: 166 IKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENC-----GKNAPFYLND 220
            ++ +  PEG++  +EV R    Y RD   +A  L      C+ C     G+  P     
Sbjct: 169 FREVIGLPEGAKVRIEVNR----YERDRRNRAAALAIHGYSCKACDLDMGGRYGPVAAG- 223

Query: 221 GNPYLEVHHVIPLSSGG----ADTTDNCVALCPNCHRELH 256
               +EVHH  P+S  G     D   + + LCPNCH   H
Sbjct: 224 ---LIEVHHTTPVSELGLGYIIDPKTDLIPLCPNCHSVSH 260


>UniRef50_C3IFK0 5-methylcytosine-specific restriction enzyme A n=5 Tax=Bacteria
           RepID=C3IFK0_BACTU
          Length = 260

 Score = 41.6 bits (96), Expect = 0.032,   Method: Compositional matrix adjust.
 Identities = 30/99 (30%), Positives = 45/99 (45%), Gaps = 9/99 (9%)

Query: 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIP 232
           EG+ K + V     VY R+ + +   ++     C  CG N    Y + G  ++ VHH+I 
Sbjct: 156 EGATKQINVN----VYERNSVARMKCIEHYGVNCIICGFNFEEIYGSVGKEFIHVHHLIE 211

Query: 233 LSSGG----ADTTDNCVALCPNCHRELHYSKNAKELIEM 267
           L         D  ++   +CPNCH  LH  K A  + EM
Sbjct: 212 LREINEQYEVDPIEDLRPVCPNCHAILHKRKPAYSIKEM 250


>UniRef50_D0FY11 HNH homing endonuclease n=1 Tax=Dunaliella salina
           RepID=D0FY11_DUNSA
          Length = 293

 Score = 41.6 bits (96), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 17/38 (44%), Positives = 22/38 (57%)

Query: 220 DGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHY 257
           + N Y EVHH+IP  +GG+D  +N   L  N H   HY
Sbjct: 76  NSNTYTEVHHIIPRHAGGSDDKENLTVLLYNDHVLAHY 113


>UniRef50_A0PZM8 HNH endonuclease domain protein n=3 Tax=Bacteria RepID=A0PZM8_CLONN
          Length = 299

 Score = 41.2 bits (95), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 3/48 (6%)

Query: 207 CENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254
           C+ CG +     ++ N  LE+ H+IP+S GG  T  N   LC  C+R+
Sbjct: 249 CQKCGLSTR---DEKNLLLEIDHIIPISKGGMSTEKNLQTLCWKCNRK 293


>UniRef50_B7K703 RNA-directed DNA polymerase (Reverse transcriptase) n=85
           Tax=Bacteria RepID=B7K703_CYAP7
          Length = 661

 Score = 41.2 bits (95), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 22/56 (39%), Positives = 31/56 (55%), Gaps = 5/56 (8%)

Query: 199 ILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254
           +L++ KG C +CG     +  +G+  LEV H+IP S GG D   N   L  +CH E
Sbjct: 526 LLKKQKGKCAHCG----LFFKEGDK-LEVDHIIPKSLGGRDEYKNWQLLHRHCHDE 576


>UniRef50_D1VIW4 HNH endonuclease n=2 Tax=Actinomycetales RepID=D1VIW4_9ACTO
          Length = 98

 Score = 41.2 bits (95), Expect = 0.036,   Method: Compositional matrix adjust.
 Identities = 23/60 (38%), Positives = 29/60 (48%), Gaps = 9/60 (15%)

Query: 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254
           VKA + Q+  G C  C             YLE  HVIP S GGA + +N   LC  C++E
Sbjct: 43  VKAAVWQRDGGACTQC---------RATEYLEFDHVIPHSLGGATSINNLQLLCRRCNQE 93


>UniRef50_A8LGA4 Stress protein n=1 Tax=Frankia sp. EAN1pec RepID=A8LGA4_FRASN
          Length = 560

 Score = 41.2 bits (95), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 23/60 (38%), Positives = 28/60 (46%), Gaps = 9/60 (15%)

Query: 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254
           VKA + Q+  G C  C             YLE  HVIP S GGA + +N   LC  C+ E
Sbjct: 505 VKAEVWQRDGGACVQC---------QATEYLEFDHVIPHSRGGASSVNNLQLLCRRCNLE 555


>UniRef50_A7C7H9 HNH endonuclease n=2 Tax=Gammaproteobacteria RepID=A7C7H9_9GAMM
          Length = 101

 Score = 41.2 bits (95), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 7/69 (10%)

Query: 216 FYLNDGNPYLEVHHVIPLSSGGA----DTTDNCVALCPNCHRELHYSK---NAKELIEML 268
           FY + G  Y+ VHH+IPL+        D   + V LCPNCH  +H ++     ++L E L
Sbjct: 29  FYGSIGKKYIHVHHIIPLAEIKKEYQLDPLKDLVPLCPNCHAMIHRTQPTLTIQQLKEYL 88

Query: 269 YVNINRLQK 277
             N    QK
Sbjct: 89  AENGKNTQK 97


>UniRef50_B7IHZ5 HNH endonuclease domain protein n=1 Tax=Thermosipho africanus
           TCF52B RepID=B7IHZ5_THEAB
          Length = 423

 Score = 41.2 bits (95), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 17/35 (48%), Positives = 20/35 (57%)

Query: 225 LEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSK 259
           LEVHH+IP S GG D   N + L    H+ LH  K
Sbjct: 203 LEVHHIIPRSKGGTDNPSNLIVLTAEEHKALHEGK 237


>UniRef50_C1SP87 Predicted restriction endonuclease n=1 Tax=Denitrovibrio
           acetiphilus DSM 12809 RepID=C1SP87_9BACT
          Length = 244

 Score = 41.2 bits (95), Expect = 0.042,   Method: Compositional matrix adjust.
 Identities = 32/106 (30%), Positives = 44/106 (41%), Gaps = 10/106 (9%)

Query: 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIP 232
           EG++  V V     +Y RD   +   L+     C  CG N    Y   G  ++  HH+ P
Sbjct: 141 EGAKTTVTVN----IYERDHDARTKCLESQGCTCSVCGFNFEQAYGLMGIDFIHTHHITP 196

Query: 233 LSSGGA----DTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINR 274
            S        D   + V LCPNCH  +H  K+    IE L   + R
Sbjct: 197 PSEIDKNYIPDPAKDLVPLCPNCHAMIH-RKSPPYTIEQLRAKLRR 241


>UniRef50_A3Z7E0 HIT family protein n=6 Tax=Synechococcus RepID=A3Z7E0_9SYNE
          Length = 314

 Score = 41.2 bits (95), Expect = 0.044,   Method: Compositional matrix adjust.
 Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 6/57 (10%)

Query: 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNC 251
           ++  +  ++KG CE CG +      +    LEV H+IP + GG+D   N  ALC  C
Sbjct: 117 IRYRVFTRAKGRCECCGAH------EHQAALEVDHIIPKNHGGSDDISNFQALCFRC 167


>UniRef50_Q0SGX7 Possible endonuclease n=37 Tax=Actinomycetales RepID=Q0SGX7_RHOSR
          Length = 250

 Score = 40.8 bits (94), Expect = 0.047,   Method: Compositional matrix adjust.
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 11/66 (16%)

Query: 190 VRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCP 249
            R PM +A ++ + +  C  CG  A            V HV+P S GG  + +NCVA C 
Sbjct: 149 ARVPMTRAALMHRDRFRCAYCGAKAE----------TVDHVVPRSRGGEHSWENCVACCA 198

Query: 250 NC-HRE 254
            C HR+
Sbjct: 199 PCNHRK 204


>UniRef50_D1P9G2 5-methylcytosine-specific restriction enzyme A n=1 Tax=Prevotella
           copri DSM 18205 RepID=D1P9G2_9BACT
          Length = 251

 Score = 40.8 bits (94), Expect = 0.047,   Method: Compositional matrix adjust.
 Identities = 28/98 (28%), Positives = 48/98 (48%), Gaps = 9/98 (9%)

Query: 172 QPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN--APFYLNDGNPYLEVHH 229
           + EG RK +  E    V  R+P ++   L +    C+ CG +    +    G  ++EVHH
Sbjct: 133 ETEGERKHILKE--TDVIRRNPQLRQMCLDKYGYQCQCCGMDFEETYGKELGVNFMEVHH 190

Query: 230 VIPLSSGGADTT-----DNCVALCPNCHRELHYSKNAK 262
           +  +S+   D       +N V LC NCH  +H+ K+++
Sbjct: 191 IRMISTYETDGVPENFLENLVPLCSNCHSMIHHIKDSE 228


>UniRef50_C8WNF9 HNH endonuclease n=1 Tax=Eggerthella lenta DSM 2243
           RepID=C8WNF9_EGGLE
          Length = 240

 Score = 40.8 bits (94), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 9/65 (13%)

Query: 199 ILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258
           I+++    C+NCGK  P  +      L++ H++P++ GG     N   LC  C+     S
Sbjct: 180 IMERDNCTCQNCGKYMPDRVG-----LQIDHIVPVARGGKTVESNLQVLCSRCNG----S 230

Query: 259 KNAKE 263
           K AKE
Sbjct: 231 KGAKE 235


>UniRef50_B7KJQ0 Reverse transcriptase n=1 Tax=Cyanothece sp. PCC 7424
           RepID=B7KJQ0_CYAP7
          Length = 43

 Score = 40.8 bits (94), Expect = 0.049,   Method: Composition-based stats.
 Identities = 16/38 (42%), Positives = 24/38 (63%)

Query: 225 LEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAK 262
           +E HH+ PL  GG+D T+N V L   CH+++H    +K
Sbjct: 1   METHHLKPLKDGGSDDTENLVHLHAACHKQVHSKTKSK 38


>UniRef50_C3XKK9 Restriction endonuclease n=1 Tax=Helicobacter winghamensis ATCC
           BAA-430 RepID=C3XKK9_9HELI
          Length = 400

 Score = 40.8 bits (94), Expect = 0.049,   Method: Compositional matrix adjust.
 Identities = 26/94 (27%), Positives = 37/94 (39%), Gaps = 17/94 (18%)

Query: 179 PVEVERLQK-----------VYVRDPMVKAWILQQSKGICENCG-----KNAPFYLNDGN 222
           P E+E+++K            + RD  +       S  IC  C      ++  F    G 
Sbjct: 258 PYEIEKIRKDLAFEKENDKESFSRDGQIVKIFKYSSDDICAACNDYYDIQDRSFLTKMGR 317

Query: 223 PYLEVHHVIPLSSGGA-DTTDNCVALCPNCHREL 255
            Y E+HH I +      D  +N   LCP CHR L
Sbjct: 318 YYTEIHHCISVGKDKQLDVLENLTKLCPVCHRAL 351


>UniRef50_C3IFK4 5-methylcytosine-specific restriction enzyme A n=1 Tax=Bacillus
           thuringiensis IBL 4222 RepID=C3IFK4_BACTU
          Length = 328

 Score = 40.8 bits (94), Expect = 0.049,   Method: Compositional matrix adjust.
 Identities = 23/60 (38%), Positives = 34/60 (56%), Gaps = 8/60 (13%)

Query: 224 YLEVHHVIPLS-----SGGADTTDNCVALCPNCHRELHYS--KNAKELIEMLY-VNINRL 275
           Y+E HH+IP+          D   N ++LC  CH++LH++  K  + LI+ LY   INRL
Sbjct: 252 YVEAHHLIPMGFQDDFQKSIDVEANIISLCAYCHKKLHHAEYKVIEPLIKKLYDARINRL 311


>UniRef50_C2D7Q9 Putative uncharacterized protein n=1 Tax=Atopobium vaginae DSM
           15829 RepID=C2D7Q9_9ACTN
          Length = 82

 Score = 40.8 bits (94), Expect = 0.049,   Method: Composition-based stats.
 Identities = 13/37 (35%), Positives = 24/37 (64%)

Query: 223 PYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSK 259
           P  +VHH+ P++ GG    +N ++LC +CH ++H  +
Sbjct: 4   PVEQVHHIKPIAEGGTHARENLISLCKSCHSKIHAKR 40


>UniRef50_B8FNE6 HNH endonuclease n=6 Tax=Deltaproteobacteria RepID=B8FNE6_DESAA
          Length = 126

 Score = 40.8 bits (94), Expect = 0.054,   Method: Compositional matrix adjust.
 Identities = 23/76 (30%), Positives = 39/76 (51%), Gaps = 8/76 (10%)

Query: 177 RKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSG 236
           R  ++ ER +   +R    + W  Q +KG+C  CG++  F  +D    L + H++P++ G
Sbjct: 25  RDSLKAEREKAREMR--ASQWWKRQLAKGVCHYCGRD--FKPSD----LTMDHLVPVARG 76

Query: 237 GADTTDNCVALCPNCH 252
           G  T  N V  C  C+
Sbjct: 77  GKTTKGNVVCACKECN 92


>UniRef50_Q60BH4 Putative uncharacterized protein n=1 Tax=Methylococcus capsulatus
           RepID=Q60BH4_METCA
          Length = 311

 Score = 40.8 bits (94), Expect = 0.055,   Method: Compositional matrix adjust.
 Identities = 31/116 (26%), Positives = 50/116 (43%), Gaps = 21/116 (18%)

Query: 165 LIKKTLSQP----EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLND 220
           L+ + + +P    EG+ K + V      Y R+P  +   ++     C  CG    F  ++
Sbjct: 198 LLPEQIDEPQEFYEGASKSITV----NAYERNPQARNACIEHYGAKCIICG----FVFHE 249

Query: 221 -----GNPYLEVHHVIPLSSGGA----DTTDNCVALCPNCHRELHYSKNAKELIEM 267
                G  ++ VHH+ PL    A    D  ++   +CPNCH  LH  K    L E+
Sbjct: 250 KYGEIGKGFIHVHHIKPLGEICAEYQVDPINDLCPVCPNCHAMLHMRKPPYSLNEI 305


>UniRef50_A6XRX8 Putative uncharacterized protein n=1 Tax=Vibrio cholerae AM-19226
           RepID=A6XRX8_VIBCH
          Length = 243

 Score = 40.8 bits (94), Expect = 0.055,   Method: Compositional matrix adjust.
 Identities = 14/31 (45%), Positives = 22/31 (70%)

Query: 225 LEVHHVIPLSSGGADTTDNCVALCPNCHREL 255
           +E+HH+ P + GGADT  N + LC +CH ++
Sbjct: 30  IEIHHIKPRADGGADTFQNAIPLCFDCHADM 60


>UniRef50_B9LX84 HNH endonuclease n=1 Tax=Halorubrum lacusprofundi ATCC 49239
           RepID=B9LX84_HALLT
          Length = 299

 Score = 40.8 bits (94), Expect = 0.056,   Method: Compositional matrix adjust.
 Identities = 23/73 (31%), Positives = 31/73 (42%), Gaps = 14/73 (19%)

Query: 184 RLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDN 243
           R +KVY RD              C+ CG       + GN  L  HH  P S GG+    N
Sbjct: 12  RRKKVYKRDNYR-----------CQKCGSRGG---SRGNTELHAHHKKPKSKGGSHRFSN 57

Query: 244 CVALCPNCHRELH 256
              +C +CH ++H
Sbjct: 58  LTTVCKSCHEDIH 70


>UniRef50_C8WWQ2 HNH endonuclease n=27 Tax=Bacteria RepID=C8WWQ2_ALIAD
          Length = 427

 Score = 40.4 bits (93), Expect = 0.060,   Method: Compositional matrix adjust.
 Identities = 34/121 (28%), Positives = 55/121 (45%), Gaps = 19/121 (15%)

Query: 158 LNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCG-KNAPF 216
           L+M++     + L  PE S +  +   L    VR+ +++ W  +     C  CG +N P 
Sbjct: 157 LSMQLVSFDTQKLQYPEISGEEYQQGTLYGYEVREYLLEKWGRK-----CAYCGAENVP- 210

Query: 217 YLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQ 276
                   LE+ HVIP S GG+D   N V  C  C++    +K  + + E L  +  RL 
Sbjct: 211 --------LEIDHVIPRSRGGSDRVSNLVLACHRCNQ----AKANRPVEEFLAHDQERLH 258

Query: 277 K 277
           +
Sbjct: 259 R 259


>UniRef50_A0YZ73 RNA-directed DNA polymerase n=1 Tax=Lyngbya sp. PCC 8106
           RepID=A0YZ73_9CYAN
          Length = 179

 Score = 40.4 bits (93), Expect = 0.061,   Method: Compositional matrix adjust.
 Identities = 32/127 (25%), Positives = 55/127 (43%), Gaps = 14/127 (11%)

Query: 131 IYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVE-----RL 185
           I  D +W ++  G  +      D   L     + +++ T  + E S  P   +     + 
Sbjct: 43  INKDKYWRTV--GNKNWCFSTEDGLELFTHSSTPIVRHTKVKGEAS--PFNGDWTYWSKR 98

Query: 186 QKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCV 245
           +  Y + P   + ++++ KGIC +CG     Y    +  +EV H+ P S GG D  DN  
Sbjct: 99  RGKYPKTPKRVSRLIKKQKGICPHCG----LYFTSTDS-VEVDHIQPTSLGGKDIYDNLQ 153

Query: 246 ALCPNCH 252
            L  +CH
Sbjct: 154 LLHKHCH 160


>UniRef50_C0EP64 Putative uncharacterized protein n=1 Tax=Neisseria flavescens
           NRL30031/H210 RepID=C0EP64_NEIFL
          Length = 106

 Score = 40.4 bits (93), Expect = 0.063,   Method: Compositional matrix adjust.
 Identities = 16/37 (43%), Positives = 23/37 (62%)

Query: 226 EVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAK 262
           E  H++PL+ GGAD  +N   LC +CH E   S+N +
Sbjct: 65  ECDHIVPLADGGADDVENLQTLCKDCHLEKSVSENRR 101


>UniRef50_A0Y4N4 Putative uncharacterized protein n=1 Tax=Alteromonadales bacterium
           TW-7 RepID=A0Y4N4_9GAMM
          Length = 430

 Score = 40.4 bits (93), Expect = 0.063,   Method: Compositional matrix adjust.
 Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 6/68 (8%)

Query: 198 WILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHY 257
           +I  +  G C +CGK    Y  +      VHHV+    GG    DN V LC  CH  +H 
Sbjct: 13  FIWHRQNGRCGSCGK--EIYAKE----FAVHHVLNCKDGGKGHIDNGVLLCCECHDNVHS 66

Query: 258 SKNAKELI 265
           +   +E I
Sbjct: 67  NARFRESI 74


>UniRef50_Q188V0 Group II intron reverse transcriptase/maturase n=7 Tax=Firmicutes
           RepID=Q188V0_CLOD6
          Length = 609

 Score = 40.4 bits (93), Expect = 0.064,   Method: Compositional matrix adjust.
 Identities = 26/74 (35%), Positives = 37/74 (50%), Gaps = 8/74 (10%)

Query: 186 QKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCV 245
           + V   D  +  +I QQ K  C   G+N    L+  N  +EVHH+ PLS GG D   N V
Sbjct: 506 KSVEFNDNRISLFIAQQGK--CHVSGEN----LSKDN--MEVHHIKPLSLGGNDNYKNLV 557

Query: 246 ALCPNCHRELHYSK 259
            +    H+ +H +K
Sbjct: 558 IVTKETHKLIHATK 571


>UniRef50_B5W3B8 HNH endonuclease n=1 Tax=Arthrospira maxima CS-328
           RepID=B5W3B8_SPIMA
          Length = 80

 Score = 40.4 bits (93), Expect = 0.066,   Method: Composition-based stats.
 Identities = 25/80 (31%), Positives = 34/80 (42%), Gaps = 18/80 (22%)

Query: 177 RKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSG 236
           ++P E ++ QK+          + Q+    CE CGK               HHVI  S G
Sbjct: 8   KRPNEHKKAQKL----------VKQRDGNECEICGKIGEI--------AHGHHVIAYSDG 49

Query: 237 GADTTDNCVALCPNCHRELH 256
           G     N + LCP+CHR  H
Sbjct: 50  GPADLTNMMTLCPDCHRAYH 69


>UniRef50_Q8VUW2 Putative uncharacterized protein 5'-methylcytosine-specific
           restiction enxyme A of Methanosarcima mazei n=1
           Tax=Staphylococcus hominis RepID=Q8VUW2_STAHO
          Length = 211

 Score = 40.4 bits (93), Expect = 0.071,   Method: Compositional matrix adjust.
 Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 5/67 (7%)

Query: 207 CENCGKN-APFYLNDGNPYLEVHHVIPLSSGGADTTDN----CVALCPNCHRELHYSKNA 261
           C+ CG N    Y N G  ++E+HH+ P+     +   N     + LC NCH+ +H SK  
Sbjct: 138 CKVCGFNFEKKYGNIGKNFIEIHHIKPMYDIRKEILVNPQTDLIPLCSNCHKMIHRSKRK 197

Query: 262 KELIEML 268
              IE L
Sbjct: 198 PYTIEQL 204


>UniRef50_B2ZY24 HNH endonuclease n=1 Tax=Ralstonia phage RSL1 RepID=B2ZY24_9CAUD
          Length = 105

 Score = 40.4 bits (93), Expect = 0.074,   Method: Compositional matrix adjust.
 Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 16/64 (25%)

Query: 199 ILQQSKGICE------NCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252
           + ++S G+CE       CGK             +VHH++ LS GG ++  N + LC +CH
Sbjct: 43  VEKRSGGLCEARIAGVRCGKRGK----------DVHHIVKLSDGGTNSMANLIHLCEDCH 92

Query: 253 RELH 256
              H
Sbjct: 93  DRRH 96


>UniRef50_B9ZDV6 HNH endonuclease n=1 Tax=Natrialba magadii ATCC 43099
           RepID=B9ZDV6_NATMA
          Length = 282

 Score = 40.0 bits (92), Expect = 0.076,   Method: Compositional matrix adjust.
 Identities = 19/67 (28%), Positives = 33/67 (49%), Gaps = 8/67 (11%)

Query: 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254
           ++   L++    C  CG +        +  L+ HH++P S+GG D  +N + LC  CH  
Sbjct: 62  LRQQTLRRDNYACTRCGAD--------DRTLQAHHIVPRSAGGPDELENLLTLCRPCHGV 113

Query: 255 LHYSKNA 261
           +H   +A
Sbjct: 114 IHQHNSA 120


>UniRef50_Q3EQP7 5-methylcytosine-specific restriction enzyme A n=1 Tax=Bacillus
           thuringiensis serovar israelensis ATCC 35646
           RepID=Q3EQP7_BACTI
          Length = 186

 Score = 40.0 bits (92), Expect = 0.077,   Method: Compositional matrix adjust.
 Identities = 23/60 (38%), Positives = 34/60 (56%), Gaps = 8/60 (13%)

Query: 224 YLEVHHVIPLS-----SGGADTTDNCVALCPNCHRELHYS--KNAKELIEMLY-VNINRL 275
           Y+E HH+IP+          D   N ++LC  CH++LH++  K  + LI+ LY   INRL
Sbjct: 110 YVEAHHLIPMGFQDDFQKSIDVEANIISLCAYCHKKLHHAEYKVIEPLIKKLYDARINRL 169


>UniRef50_Q8YYJ2 Alr0856 protein n=6 Tax=Cyanobacteria RepID=Q8YYJ2_ANASP
          Length = 181

 Score = 40.0 bits (92), Expect = 0.078,   Method: Compositional matrix adjust.
 Identities = 27/74 (36%), Positives = 35/74 (47%), Gaps = 12/74 (16%)

Query: 178 KPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGG 237
           K   VER  KV    P+ +  IL++    C+ CG            +L + HVIP S GG
Sbjct: 68  KITSVERTWKV---PPVNRREILRRDHHSCQYCGSRK---------HLTLDHVIPRSRGG 115

Query: 238 ADTTDNCVALCPNC 251
           + T DN VA C  C
Sbjct: 116 SHTWDNVVAACERC 129


>UniRef50_D2S3N7 Putative uncharacterized protein n=1 Tax=Haloterrigena turkmenica
           DSM 5511 RepID=D2S3N7_9EURY
          Length = 193

 Score = 40.0 bits (92), Expect = 0.082,   Method: Compositional matrix adjust.
 Identities = 21/61 (34%), Positives = 33/61 (54%), Gaps = 1/61 (1%)

Query: 217 YLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQ 276
           Y  + +  LE HH+ P   GG+D+ DN V +C +CH +L    N K+  E L ++  R  
Sbjct: 12  YFCESSDDLEEHHIAPQRLGGSDSRDNLVIVCHDCHWKLERLYN-KDFYEQLGIDDPRTT 70

Query: 277 K 277
           +
Sbjct: 71  R 71


>UniRef50_Q9RZ97 TerF-related protein n=1 Tax=Deinococcus radiodurans
           RepID=Q9RZ97_DEIRA
          Length = 579

 Score = 40.0 bits (92), Expect = 0.083,   Method: Compositional matrix adjust.
 Identities = 24/58 (41%), Positives = 29/58 (50%), Gaps = 9/58 (15%)

Query: 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252
           VK  + Q+ +G C  CG        D N YLE  HVIP S GGA +  N   LC  C+
Sbjct: 524 VKLEVWQRDQGQCVECG--------DTN-YLEFDHVIPHSLGGASSVGNLQLLCRRCN 572


>UniRef50_B8GWL7 Hypothetical cytosolic protein n=2 Tax=Caulobacter vibrioides
           RepID=B8GWL7_CAUCN
          Length = 172

 Score = 40.0 bits (92), Expect = 0.091,   Method: Compositional matrix adjust.
 Identities = 14/48 (29%), Positives = 30/48 (62%)

Query: 225 LEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNI 272
           +++HH++P  +  A   +N +ALCPNCHR     +  ++ +++  +N+
Sbjct: 38  VDIHHIVPWRTCQAHEYENLIALCPNCHRRADREEIDRKSLKLYKLNL 85


>UniRef50_A2SPF2 Putative uncharacterized protein n=1 Tax=Methanocorpusculum
           labreanum Z RepID=A2SPF2_METLZ
          Length = 95

 Score = 40.0 bits (92), Expect = 0.093,   Method: Compositional matrix adjust.
 Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 5/56 (8%)

Query: 200 LQQSKGICENCGKNAPFYLNDGNPY----LEVHHVIPLSSGGADTTDNCVALCPNC 251
            ++  G C+ CGK    Y N GN       +  H+ P+S GG D   NC+ LC +C
Sbjct: 12  FEKVNGYCQICGKKL-IYANRGNAVGRGGWDAKHIKPVSDGGKDEVRNCMILCMDC 66


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_P24200 5-methylcytosine-specific restriction enzyme A n...   518   e-146
UniRef50_A9BU78 HNH endonuclease n=4 Tax=Burkholderiales RepID=A...   158   2e-37
UniRef50_A0KIQ7 Probable 5-methylcytosine-specific restriction e...   156   8e-37
UniRef50_C3K0B7 Putative 5-methylcytosine-specific restriction e...   152   9e-36
UniRef50_Q2Y8M1 HNH nuclease n=1 Tax=Nitrosospira multiformis AT...   147   4e-34
UniRef50_A6QD09 5-methylcytosine-specific restriction enzyme A n...   147   5e-34
UniRef50_UPI00016A2859 HNH endonuclease n=1 Tax=Burkholderia tha...   146   8e-34
UniRef50_Q1YK78 Putative 5-methylcytosine-specific restriction e...   146   9e-34
UniRef50_B5EI94 HNH endonuclease n=1 Tax=Geobacter bemidjiensis ...   137   4e-31
UniRef50_C4WNE8 Putative uncharacterized protein n=1 Tax=Ochroba...   135   1e-30
UniRef50_C3FAM5 HNH nuclease n=4 Tax=Bacillus cereus group RepID...   134   3e-30
UniRef50_D0Z3H8 HNH nuclease n=1 Tax=Photobacterium damselae sub...   134   4e-30
UniRef50_Q080H4 HNH endonuclease n=1 Tax=Shewanella frigidimarin...   133   7e-30
UniRef50_C0WRI9 Possible HNH endonuclease n=1 Tax=Lactobacillus ...   131   2e-29
UniRef50_A2SMM5 Putative uncharacterized protein n=1 Tax=Methyli...   130   5e-29
UniRef50_Q3K870 Putative 5-methylcytosine-specific restriction e...   130   6e-29
UniRef50_Q0BZ66 Conserved domain protein n=1 Tax=Hyphomonas nept...   129   1e-28
UniRef50_C4SUH5 Restriction endonuclease n=1 Tax=Yersinia freder...   129   1e-28
UniRef50_A3JQK6 HNH nuclease n=1 Tax=Rhodobacterales bacterium H...   128   2e-28
UniRef50_D0KA86 HNH endonuclease n=2 Tax=Enterobacteriaceae RepI...   128   2e-28
UniRef50_D2C2V7 HNH endonuclease n=1 Tax=Dickeya dadantii Ech586...   128   2e-28
UniRef50_A4SC99 HNH endonuclease n=1 Tax=Chlorobium phaeovibrioi...   128   3e-28
UniRef50_C0N619 HNH endonuclease domain protein n=1 Tax=Methylop...   127   6e-28
UniRef50_C7HJ98 HNH endonuclease n=1 Tax=Clostridium thermocellu...   126   8e-28
UniRef50_A8ZWC1 HNH endonuclease n=1 Tax=Desulfococcus oleovoran...   124   3e-27
UniRef50_C6ANH6 HNH nuclease n=1 Tax=Aggregatibacter aphrophilus...   123   8e-27
UniRef50_C3C627 Restriction endonuclease n=7 Tax=Bacillus RepID=...   122   1e-26
UniRef50_C9PPM2 5-methylcytosine-specific restriction enzyme A n...   122   2e-26
UniRef50_Q312Y0 HNH nuclease n=1 Tax=Desulfovibrio desulfuricans...   122   2e-26
UniRef50_A6VSV6 HNH endonuclease n=1 Tax=Marinomonas sp. MWYL1 R...   120   5e-26
UniRef50_Q1QEV2 HNH endonuclease n=5 Tax=Gammaproteobacteria Rep...   120   7e-26
UniRef50_C2KXT9 Putative uncharacterized protein n=1 Tax=Oribact...   117   5e-25
UniRef50_C9XQW3 Putative uncharacterized protein n=2 Tax=Clostri...   116   1e-24
UniRef50_C2ECC9 Recombinase n=1 Tax=Lactobacillus ruminis ATCC 2...   115   1e-24
UniRef50_B4S2Y7 HNH nuclease n=2 Tax=Proteobacteria RepID=B4S2Y7...   115   1e-24
UniRef50_D2S1X8 HNH endonuclease n=1 Tax=Haloterrigena turkmenic...   107   3e-22
UniRef50_D1NJY2 Transcriptional regulator, XRE family n=1 Tax=Cl...   107   3e-22
UniRef50_C4L1L5 HNH endonuclease n=2 Tax=Bacillales RepID=C4L1L5...   107   3e-22
UniRef50_Q9L0M9 Putative uncharacterized protein SCO4631 n=3 Tax...   107   4e-22
UniRef50_A8R8M0 Putative uncharacterized protein n=1 Tax=Eubacte...   105   2e-21
UniRef50_A3US95 Putative restriction endonuclease n=1 Tax=Vibrio...   104   2e-21
UniRef50_C9BZK6 Restriction endonuclease (Fragment) n=4 Tax=Firm...   104   3e-21
UniRef50_A9F818 Putative restriction endonuclease n=1 Tax=Phaeob...   104   4e-21
UniRef50_C0QGN0 Putative 5-methylcytosine-specific restriction e...   104   4e-21
UniRef50_C4L074 HNH endonuclease n=1 Tax=Exiguobacterium sp. AT1...   104   5e-21
UniRef50_A3WFM1 5-methylcytosine-specific restriction enzyme A n...   102   1e-20
UniRef50_Q0KFQ5 Predicted restriction endonuclease n=1 Tax=Ralst...   101   2e-20
UniRef50_UPI0001A457FB putative 5-methylcytosine-specific restri...   101   3e-20
UniRef50_Q723Z7 Conserved domain protein n=4 Tax=Listeria monocy...   101   3e-20
UniRef50_B1ZMM6 HNH endonuclease n=1 Tax=Opitutus terrae PB90-1 ...   100   4e-20
UniRef50_Q1L9I8 HNH nuclease n=2 Tax=cellular organisms RepID=Q1...   100   5e-20
UniRef50_B1ZSH9 Restriction endonuclease-like protein n=1 Tax=Op...   100   6e-20
UniRef50_Q8TKB6 Hnh endonuclease n=2 Tax=Methanosarcina RepID=Q8...   100   9e-20
UniRef50_Q65MN2 McrA n=2 Tax=Bacillus subtilis group RepID=Q65MN...    99   1e-19
UniRef50_B0ACA5 Putative uncharacterized protein n=1 Tax=Clostri...    99   2e-19
UniRef50_A0L1U4 HNH endonuclease n=1 Tax=Shewanella sp. ANA-3 Re...    99   2e-19
UniRef50_C3RB64 Predicted protein n=1 Tax=Bacteroides dorei 5_1_...    98   3e-19
UniRef50_A3U4A6 E14 prophage-like protein n=1 Tax=Oceanicola bat...    97   4e-19
UniRef50_C6MKA5 HNH endonuclease n=1 Tax=Geobacter sp. M18 RepID...    97   6e-19
UniRef50_B3EB35 HNH endonuclease n=1 Tax=Geobacter lovleyi SZ Re...    97   6e-19
UniRef50_B8KVR3 HNH endonuclease domain protein n=1 Tax=gamma pr...    97   6e-19
UniRef50_C8U495 Endonuclease-like protein n=2 Tax=Escherichia co...    97   7e-19
UniRef50_Q3K789 Putative HNH endonuclease n=1 Tax=Pseudomonas fl...    97   9e-19
UniRef50_B0N4T9 Putative uncharacterized protein n=1 Tax=Clostri...    96   9e-19
UniRef50_Q81E47 5-methylcytosine-specific restriction enzyme A n...    96   2e-18
UniRef50_C6LDW0 Product McrA n=1 Tax=Bryantella formatexigens DS...    94   4e-18
UniRef50_B3CDE4 Putative uncharacterized protein n=1 Tax=Bactero...    94   4e-18
UniRef50_D1BJK4 HNH endonuclease n=1 Tax=Sanguibacter keddieii D...    94   4e-18
UniRef50_C0ZFI2 Putative uncharacterized protein n=1 Tax=Breviba...    94   7e-18
UniRef50_B5G9G0 HNH endonuclease n=1 Tax=Streptomyces sp. SPB74 ...    92   3e-17
UniRef50_Q64YP3 Putative uncharacterized protein n=1 Tax=Bactero...    89   2e-16
UniRef50_Q0HF94 Putative uncharacterized protein n=1 Tax=Shewane...    89   2e-16
UniRef50_A0YK66 Putative uncharacterized protein n=1 Tax=Lyngbya...    88   3e-16
UniRef50_C7V3C1 Predicted protein n=1 Tax=Enterococcus faecalis ...    87   6e-16
UniRef50_Q5YRW6 Putative endonuclease n=1 Tax=Nocardia farcinica...    86   2e-15
UniRef50_Q46AN8 Putative uncharacterized protein n=1 Tax=Methano...    85   3e-15
UniRef50_Q39IU3 Putative uncharacterized protein n=1 Tax=Burkhol...    76   1e-12
UniRef50_Q6MJA3 Putative membrane protein n=1 Tax=Bdellovibrio b...    76   2e-12
UniRef50_Q3EYN0 HNH endonuclease family protein n=1 Tax=Bacillus...    75   3e-12
UniRef50_C3GU40 HNH endonuclease n=2 Tax=Bacillus thuringiensis ...    75   3e-12
UniRef50_Q3IBU7 Putative HNH endonuclease n=1 Tax=Pseudoalteromo...    71   4e-11
UniRef50_Q8DK67 Reverse transcriptase n=1 Tax=Thermosynechococcu...    70   7e-11
UniRef50_A0ZAT3 Putative uncharacterized protein n=1 Tax=Nodular...    69   2e-10
UniRef50_A6TVA6 HNH endonuclease n=6 Tax=Bacteria RepID=A6TVA6_A...    67   4e-10
UniRef50_C9RBS6 HNH endonuclease n=4 Tax=Ammonifex degensii KC4 ...    67   7e-10
UniRef50_C3AFV2 Putative uncharacterized protein n=1 Tax=Bacillu...    67   7e-10
UniRef50_Q538B5 MnlI restriction endonuclease n=2 Tax=Moraxella ...    65   2e-09
UniRef50_A3YQ82 MnlI restriction endonuclease n=1 Tax=Campylobac...    65   3e-09

Sequences not found previously or not previously below threshold:

UniRef50_Q60BH4 Putative uncharacterized protein n=1 Tax=Methylo...    96   1e-18
UniRef50_UPI0001BC7B91 HNH endonuclease n=1 Tax=Bacteroides sp. ...    93   9e-18
UniRef50_B9DID5 Putative uncharacterized protein n=1 Tax=Staphyl...    93   9e-18
UniRef50_Q0AUW7 Hnh endonuclease n=1 Tax=Syntrophomonas wolfei s...    93   1e-17
UniRef50_C3G8U4 HNH endonuclease n=1 Tax=Bacillus thuringiensis ...    92   2e-17
UniRef50_A0YCZ6 Putative uncharacterized protein n=1 Tax=marine ...    91   3e-17
UniRef50_D1P9G2 5-methylcytosine-specific restriction enzyme A n...    91   4e-17
UniRef50_C4UQ38 Putative uncharacterized protein n=1 Tax=Yersini...    91   4e-17
UniRef50_C5RG47 HNH endonuclease n=1 Tax=Clostridium cellulovora...    91   5e-17
UniRef50_A9AZQ2 HNH endonuclease n=1 Tax=Herpetosiphon aurantiac...    91   5e-17
UniRef50_UPI0001BC350E HNH endonuclease n=1 Tax=Butyrivibrio cro...    90   8e-17
UniRef50_C9ADX3 5-methylcytosine-specific restriction enzyme A n...    90   9e-17
UniRef50_A9GYN9 Putative uncharacterized protein n=1 Tax=Roseoba...    90   1e-16
UniRef50_A7I926 HNH endonuclease n=1 Tax=Candidatus Methanoregul...    89   1e-16
UniRef50_Q8VUW2 Putative uncharacterized protein 5'-methylcytosi...    89   2e-16
UniRef50_D2QLF4 HNH endonuclease n=1 Tax=Spirosoma linguale DSM ...    89   2e-16
UniRef50_Q6EME6 Hnh endonuclease n=6 Tax=Enterobacteriaceae RepI...    88   3e-16
UniRef50_B1QVB2 HNH endonuclease domain protein n=2 Tax=Clostrid...    88   3e-16
UniRef50_Q67M53 Conserved domain protein n=1 Tax=Symbiobacterium...    88   4e-16
UniRef50_D0IIJ2 HNH endonuclease n=1 Tax=Vibrio sp. RC586 RepID=...    86   9e-16
UniRef50_Q1YWU8 Putative uncharacterized protein n=3 Tax=Gammapr...    86   9e-16
UniRef50_A9B4I7 HNH endonuclease n=1 Tax=Herpetosiphon aurantiac...    86   1e-15
UniRef50_C0CT91 Putative uncharacterized protein n=1 Tax=Clostri...    86   2e-15
UniRef50_D2YH85 Putative uncharacterized protein n=1 Tax=Vibrio ...    86   2e-15
UniRef50_C1SP87 Predicted restriction endonuclease n=1 Tax=Denit...    85   3e-15
UniRef50_D2YGR3 Putative uncharacterized protein n=1 Tax=Vibrio ...    84   4e-15
UniRef50_B0A7V0 Putative uncharacterized protein n=1 Tax=Clostri...    84   7e-15
UniRef50_B0KIU7 HNH endonuclease n=1 Tax=Pseudomonas putida GB-1...    84   7e-15
UniRef50_C3AW04 Putative uncharacterized protein n=1 Tax=Bacillu...    84   7e-15
UniRef50_C3IFK0 5-methylcytosine-specific restriction enzyme A n...    82   2e-14
UniRef50_C3LV13 HNH endonuclease n=13 Tax=Vibrio RepID=C3LV13_VIBCM    82   2e-14
UniRef50_C8TQ55 Predicted endonuclease n=10 Tax=Enterobacteriace...    82   2e-14
UniRef50_A0KZG4 HNH endonuclease n=1 Tax=Shewanella sp. ANA-3 Re...    82   3e-14
UniRef50_C5QAR7 HNH endonuclease n=5 Tax=Firmicutes RepID=C5QAR7...    82   3e-14
UniRef50_A0JWW4 HNH endonuclease n=1 Tax=Arthrobacter sp. FB24 R...    81   3e-14
UniRef50_C3IFK4 5-methylcytosine-specific restriction enzyme A n...    81   4e-14
UniRef50_C3L8D2 Putative uncharacterized protein n=6 Tax=Bacillu...    81   4e-14
UniRef50_A1F1U9 HNH endonuclease domain protein n=1 Tax=Vibrio c...    81   5e-14
UniRef50_A7C7H9 HNH endonuclease n=2 Tax=Gammaproteobacteria Rep...    80   7e-14
UniRef50_Q5L3M3 Hnh endonuclease n=1 Tax=Geobacillus kaustophilu...    80   9e-14
UniRef50_O83027 Disrupted by IS8301 insertion n=1 Tax=Deinococcu...    80   1e-13
UniRef50_A3WCW2 HNH endonuclease n=1 Tax=Erythrobacter sp. NAP1 ...    79   1e-13
UniRef50_A5W5D0 HNH endonuclease n=4 Tax=Gammaproteobacteria Rep...    79   1e-13
UniRef50_Q3EQP7 5-methylcytosine-specific restriction enzyme A n...    79   1e-13
UniRef50_B0KGB9 Restriction endonuclease-like protein n=1 Tax=Ps...    79   2e-13
UniRef50_D1XF45 HNH endonuclease n=3 Tax=Streptomyces RepID=D1XF...    78   3e-13
UniRef50_D0S0J8 Hnh endonuclease n=1 Tax=Acinetobacter calcoacet...    77   5e-13
UniRef50_Q477P3 HNH endonuclease n=1 Tax=Ralstonia eutropha JMP1...    77   5e-13
UniRef50_B2IKM5 HNH endonuclease n=1 Tax=Beijerinckia indica sub...    77   7e-13
UniRef50_A9B5H7 HNH endonuclease n=1 Tax=Herpetosiphon aurantiac...    77   8e-13
UniRef50_UPI0001BC7063 hypothetical protein VparAQ_18636 n=1 Tax...    76   1e-12
UniRef50_A6GA77 HNH endonuclease n=1 Tax=Plesiocystis pacifica S...    76   1e-12
UniRef50_B1QVB3 HNH endonuclease domain protein n=2 Tax=Clostrid...    74   4e-12
UniRef50_C2NAK2 HNH endonuclease n=1 Tax=Bacillus cereus ATCC 10...    74   4e-12
UniRef50_Q6LSI1 Putative uncharacterized protein MLL7993 n=1 Tax...    74   6e-12
UniRef50_B5ERY9 Restriction endonuclease-like protein n=1 Tax=Ac...    74   7e-12
UniRef50_B1KV86 Hnh endonuclease n=5 Tax=Firmicutes RepID=B1KV86...    73   8e-12
UniRef50_D2AT16 Putative uncharacterized protein n=1 Tax=Strepto...    72   1e-11
UniRef50_D2QLF7 HNH endonuclease n=1 Tax=Spirosoma linguale DSM ...    72   2e-11
UniRef50_C4XM37 Putative uncharacterized protein n=1 Tax=Desulfo...    72   2e-11
UniRef50_Q984I3 Mll7993 protein n=1 Tax=Mesorhizobium loti RepID...    72   2e-11
UniRef50_A4G659 Putative restriction endonuclease n=1 Tax=Hermin...    72   2e-11
UniRef50_Q82CY5 Putative uncharacterized protein n=1 Tax=Strepto...    72   2e-11
UniRef50_B4D4V1 HNH endonuclease n=1 Tax=Chthoniobacter flavus E...    72   2e-11
UniRef50_C8S4R5 HNH endonuclease n=1 Tax=Rhodobacter sp. SW2 Rep...    72   2e-11
UniRef50_C7NQZ2 HNH endonuclease n=1 Tax=Halorhabdus utahensis D...    71   4e-11
UniRef50_C4F8E8 Putative uncharacterized protein n=1 Tax=Collins...    71   5e-11
UniRef50_B8FFI4 HNH endonuclease n=1 Tax=Desulfatibacillum alken...    71   5e-11
UniRef50_B0TQV8 Restriction endonuclease-like protein n=1 Tax=Sh...    71   6e-11
UniRef50_C3XKK9 Restriction endonuclease n=1 Tax=Helicobacter wi...    71   6e-11
UniRef50_D0C4R2 HNH endonuclease n=1 Tax=Acinetobacter sp. RUH26...    70   1e-10
UniRef50_D0WS63 Putative uncharacterized protein n=1 Tax=Vibrio ...    69   1e-10
UniRef50_Q4K9Y7 Putative uncharacterized protein n=1 Tax=Pseudom...    69   1e-10
UniRef50_A1B3Q8 HNH endonuclease n=2 Tax=Rhodobacteraceae RepID=...    69   2e-10
UniRef50_C7D6X3 Putative uncharacterized protein n=1 Tax=Thalass...    69   2e-10
UniRef50_C4ZAA3 Putative uncharacterized protein n=1 Tax=Eubacte...    69   2e-10
UniRef50_B4SCA5 HNH nuclease n=1 Tax=Pelodictyon phaeoclathratif...    69   2e-10
UniRef50_Q2FRM5 HNH endonuclease n=1 Tax=Methanospirillum hungat...    69   2e-10
UniRef50_B9JB56 Putative uncharacterized protein n=1 Tax=Agrobac...    68   4e-10
UniRef50_A5ELB4 Putative uncharacterized protein n=1 Tax=Bradyrh...    67   4e-10
UniRef50_UPI000197A09F restriction endonuclease n=1 Tax=Helicoba...    67   6e-10
UniRef50_C5ZWY1 Putative uncharacterized protein n=1 Tax=Helicob...    67   6e-10
UniRef50_UPI0000E87DB3 hypothetical protein MB2181_05395 n=1 Tax...    67   8e-10
UniRef50_B4SDY4 HNH nuclease n=4 Tax=Bacteria RepID=B4SDY4_PELPB       67   8e-10
UniRef50_B2A7T7 HNH endonuclease n=1 Tax=Natranaerobius thermoph...    66   1e-09
UniRef50_Q2FQI6 HNH endonuclease n=1 Tax=Methanospirillum hungat...    66   1e-09
UniRef50_C6WXV3 HNH endonuclease n=3 Tax=Proteobacteria RepID=C6...    66   1e-09
UniRef50_B7JSJ9 DNA helicase, putative n=1 Tax=Bacillus cereus A...    66   2e-09
UniRef50_A4W6M3 HNH endonuclease n=7 Tax=Enterobacteriaceae RepI...    65   2e-09
UniRef50_D2RK49 HNH endonuclease n=11 Tax=Bacteria RepID=D2RK49_...    65   2e-09
UniRef50_A3X5U3 Putative uncharacterized protein n=2 Tax=Alphapr...    65   3e-09
UniRef50_C3BJL8 Paclitaxel/taxanoid biosynthesis susceptibility ...    65   3e-09
UniRef50_A6FN65 HIT family protein n=5 Tax=root RepID=A6FN65_9RHOB     64   4e-09
UniRef50_B0MFF1 Putative uncharacterized protein n=1 Tax=Anaeros...    64   5e-09
UniRef50_B9PFL0 Predicted protein (Fragment) n=2 Tax=cellular or...    64   5e-09
UniRef50_A9VH89 HNH endonuclease n=3 Tax=Bacillus cereus group R...    64   6e-09
UniRef50_C4K5N9 Group II intron encoded reverse transcriptase n=...    64   7e-09
UniRef50_D2S2Y4 HNH endonuclease n=1 Tax=Haloterrigena turkmenic...    63   8e-09
UniRef50_B9LX84 HNH endonuclease n=1 Tax=Halorubrum lacusprofund...    63   9e-09
UniRef50_Q82RB7 Putative reverse transcriptase homolog; similar ...    63   1e-08
UniRef50_C6J8S5 Putative uncharacterized protein n=1 Tax=Ruminoc...    63   1e-08
UniRef50_A1ZG09 Paclitaxel/taxanoid biosynthesis susceptibility ...    62   1e-08
UniRef50_C1V6S3 HNH endonuclease n=1 Tax=Halogeometricum borinqu...    62   1e-08
UniRef50_B8I0D2 HNH endonuclease n=1 Tax=Clostridium cellulolyti...    62   2e-08
UniRef50_C1EM61 HNH endonuclease domain protein n=6 Tax=Bacillus...    62   3e-08
UniRef50_Q8YJX6 All8554 protein n=2 Tax=Cyanobacteria RepID=Q8YJ...    61   4e-08
UniRef50_A5V9C7 HNH endonuclease n=1 Tax=Sphingomonas wittichii ...    61   4e-08
UniRef50_Q9R669 Group II SELF-splicing intron ORF (Fragments) n=...    61   4e-08
UniRef50_B5W3B8 HNH endonuclease n=1 Tax=Arthrospira maxima CS-3...    61   4e-08
UniRef50_B9ZDV6 HNH endonuclease n=1 Tax=Natrialba magadii ATCC ...    61   5e-08
UniRef50_Q5YZQ8 Putative uncharacterized protein n=1 Tax=Nocardi...    61   5e-08
UniRef50_B6JPE5 Restriction endonuclease n=4 Tax=Helicobacter py...    61   5e-08
UniRef50_B0MB23 Putative uncharacterized protein n=1 Tax=Anaeros...    60   6e-08
UniRef50_B7IHZ5 HNH endonuclease domain protein n=1 Tax=Thermosi...    60   6e-08
UniRef50_Q82H00 Putative uncharacterized protein n=1 Tax=Strepto...    60   7e-08
UniRef50_A5N0L8 Phage-related protein n=15 Tax=Bacteria RepID=A5...    60   8e-08
UniRef50_Q2S547 Putative uncharacterized protein n=1 Tax=Salinib...    60   8e-08
UniRef50_Q21AN9 HNH endonuclease n=1 Tax=Rhodopseudomonas palust...    60   1e-07
UniRef50_C0EP64 Putative uncharacterized protein n=1 Tax=Neisser...    60   1e-07
UniRef50_D1S1E3 HNH nuclease n=1 Tax=Micromonospora aurantiaca A...    59   2e-07
UniRef50_B1I905 HNH endonuclease domain protein n=3 Tax=Streptoc...    59   2e-07
UniRef50_B0MB74 Putative uncharacterized protein n=1 Tax=Anaeros...    59   2e-07
UniRef50_A3HSL8 Putative uncharacterized protein n=1 Tax=Algorip...    59   2e-07
UniRef50_C6A463 Putative uncharacterized protein n=1 Tax=Thermoc...    59   2e-07
UniRef50_Q8U2D9 Putative uncharacterized protein n=1 Tax=Pyrococ...    59   2e-07
UniRef50_A0YZ73 RNA-directed DNA polymerase n=1 Tax=Lyngbya sp. ...    59   2e-07
UniRef50_C0GPK5 Restriction endonuclease n=1 Tax=Desulfonatronos...    58   3e-07
UniRef50_Q19YE9 Gp104 n=4 Tax=unclassified Siphoviridae RepID=Q1...    58   3e-07
UniRef50_A0PZM8 HNH endonuclease domain protein n=3 Tax=Bacteria...    58   3e-07
UniRef50_Q0F8W7 Putative uncharacterized protein n=1 Tax=Rhodoba...    58   4e-07
UniRef50_C6WB78 Restriction endonuclease-like protein n=1 Tax=Ac...    58   4e-07
UniRef50_B0SF14 HNH nuclease n=4 Tax=Bacteria RepID=B0SF14_LEPBA       58   4e-07
UniRef50_A3Z7E0 HIT family protein n=6 Tax=Synechococcus RepID=A...    57   5e-07
UniRef50_B2IX42 HNH endonuclease n=18 Tax=Cyanobacteria RepID=B2...    57   5e-07
UniRef50_B0VJM1 Putative ATP dependant helicase yprA n=1 Tax=Can...    57   6e-07
UniRef50_B9ZCI1 HNH endonuclease n=1 Tax=Natrialba magadii ATCC ...    57   6e-07
UniRef50_A1REN7 HNH nuclease n=1 Tax=Shewanella sp. W3-18-1 RepI...    57   6e-07
UniRef50_D0LCK0 HNH endonuclease n=3 Tax=Gordonia bronchialis DS...    57   7e-07
UniRef50_Q4C417 HNH endonuclease n=3 Tax=Crocosphaera watsonii W...    57   7e-07
UniRef50_Q94Z24 Orf568 n=1 Tax=Pylaiella littoralis RepID=Q94Z24...    57   7e-07
UniRef50_C0ZFI4 Putative uncharacterized protein n=1 Tax=Breviba...    57   8e-07
UniRef50_Q7GEU5 Putative uncharacterized protein (Fragment) n=3 ...    57   9e-07
UniRef50_Q07U56 Restriction endonuclease-like protein n=2 Tax=Br...    56   1e-06
UniRef50_B6VWC0 Putative uncharacterized protein n=1 Tax=Bactero...    56   1e-06
UniRef50_A3CWM7 HNH endonuclease n=1 Tax=Methanoculleus marisnig...    56   1e-06
UniRef50_C7NQ66 HNH endonuclease n=2 Tax=Halobacteriaceae RepID=...    56   1e-06
UniRef50_B8F0E2 Restriction endonuclease-like protein n=1 Tax=Th...    56   1e-06
UniRef50_C7Q4G6 HNH endonuclease n=1 Tax=Catenulispora acidiphil...    56   2e-06
UniRef50_Q3Z844 HNH endonuclease family protein n=1 Tax=Dehaloco...    55   2e-06
UniRef50_B0JFS6 HNH endonuclease n=2 Tax=Cyanobacteria RepID=B0J...    55   2e-06
UniRef50_D1VPN1 HNH endonuclease n=1 Tax=Frankia sp. EuI1c RepID...    55   2e-06
UniRef50_B4CXI0 HNH nuclease n=1 Tax=Chthoniobacter flavus Ellin...    55   2e-06
UniRef50_C4V188 Putative uncharacterized protein n=1 Tax=Selenom...    55   2e-06
UniRef50_D2QPK7 Restriction endonuclease n=1 Tax=Spirosoma lingu...    55   2e-06
UniRef50_Q2SDL1 Restriction endonuclease n=2 Tax=Gammaproteobact...    55   2e-06
UniRef50_Q892G5 Phage-related protein n=1 Tax=Clostridium tetani...    55   2e-06
UniRef50_B2JEA1 Restriction endonuclease-like protein n=1 Tax=Bu...    55   2e-06
UniRef50_A6XRX8 Putative uncharacterized protein n=1 Tax=Vibrio ...    55   2e-06
UniRef50_A6TQ34 Putative uncharacterized protein n=3 Tax=Firmicu...    55   3e-06
UniRef50_C1YI89 Predicted restriction endonuclease n=2 Tax=Actin...    55   3e-06
UniRef50_Q7M1J5 Reverse transcription like protein 2, intron-enc...    55   3e-06
UniRef50_UPI0001AEF119 restriction endonuclease n=1 Tax=Streptom...    55   3e-06

>UniRef50_P24200 5-methylcytosine-specific restriction enzyme A n=2 Tax=Escherichia
           coli RepID=MCRA_ECOLI
          Length = 277

 Score =  518 bits (1334), Expect = e-146,   Method: Composition-based stats.
 Identities = 277/277 (100%), Positives = 277/277 (100%)

Query: 1   MHVFDNNGIELKAECSIGEEDGVYGLILESWGPGDRNKDYNIALDYIIERLVDSGVSQVV 60
           MHVFDNNGIELKAECSIGEEDGVYGLILESWGPGDRNKDYNIALDYIIERLVDSGVSQVV
Sbjct: 1   MHVFDNNGIELKAECSIGEEDGVYGLILESWGPGDRNKDYNIALDYIIERLVDSGVSQVV 60

Query: 61  VYLASSSVRKHMHSLDERKIHPGEYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEIPSGNR 120
           VYLASSSVRKHMHSLDERKIHPGEYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEIPSGNR
Sbjct: 61  VYLASSSVRKHMHSLDERKIHPGEYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEIPSGNR 120

Query: 121 TKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPV 180
           TKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPV
Sbjct: 121 TKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPV 180

Query: 181 EVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADT 240
           EVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADT
Sbjct: 181 EVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADT 240

Query: 241 TDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277
           TDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK
Sbjct: 241 TDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277


>UniRef50_A9BU78 HNH endonuclease n=4 Tax=Burkholderiales RepID=A9BU78_DELAS
          Length = 330

 Score =  158 bits (400), Expect = 2e-37,   Method: Composition-based stats.
 Identities = 62/132 (46%), Positives = 82/132 (62%), Gaps = 1/132 (0%)

Query: 144 ELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQS 203
           ELS   Q    +    +R   L  K  ++P G+  P  + R    + RDP VKAW+L+++
Sbjct: 197 ELSNSQQAPVVKFEFQVR-ENLENKKQAKPAGNSNPGTIIRQVAQFERDPAVKAWVLKKA 255

Query: 204 KGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKE 263
            G+CE C  NAPF   DG P+LEVHH+  L+ GG+DT  N VALCPNCHR LHY   AKE
Sbjct: 256 AGVCECCSSNAPFESTDGQPFLEVHHIRKLAEGGSDTVSNTVALCPNCHRALHYGMRAKE 315

Query: 264 LIEMLYVNINRL 275
           LIE +++ +NRL
Sbjct: 316 LIESIFIKVNRL 327


>UniRef50_A0KIQ7 Probable 5-methylcytosine-specific restriction enzyme A n=1
           Tax=Aeromonas hydrophila subsp. hydrophila ATCC 7966
           RepID=A0KIQ7_AERHH
          Length = 246

 Score =  156 bits (394), Expect = 8e-37,   Method: Composition-based stats.
 Identities = 64/142 (45%), Positives = 84/142 (59%), Gaps = 2/142 (1%)

Query: 138 ASIIRGELSELS-QPTDDESLLNMRVSKL-IKKTLSQPEGSRKPVEVERLQKVYVRDPMV 195
           A II   L EL  QP   ++    +VS+  IK TL  P G ++P +       Y RDP V
Sbjct: 104 APIIERLLCELDGQPYTGKAAFEHQVSRYKIKPTLPMPIGIQEPQQRYGANTSYGRDPKV 163

Query: 196 KAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHREL 255
           KAW+L  + G CE+C + APF+   G+ +LEVHH+  L+ GG+DT  N VALCPNCHREL
Sbjct: 164 KAWVLMTAVGRCESCAQPAPFHATTGDAFLEVHHLRTLAEGGSDTISNTVALCPNCHREL 223

Query: 256 HYSKNAKELIEMLYVNINRLQK 277
           HY  N  +  E LY  + RL +
Sbjct: 224 HYGVNQAQKREALYQALPRLVR 245


>UniRef50_C3K0B7 Putative 5-methylcytosine-specific restriction enzyme n=1
           Tax=Pseudomonas fluorescens SBW25 RepID=C3K0B7_PSEFS
          Length = 237

 Score =  152 bits (385), Expect = 9e-36,   Method: Composition-based stats.
 Identities = 61/133 (45%), Positives = 83/133 (62%), Gaps = 2/133 (1%)

Query: 146 SELSQPTDDESLLNMRVSKLIKKTLSQ-PEGSRKPVEVERLQKVYVRDPMVKAWILQQSK 204
           S+ +  T DE  L  R SKL ++  +Q P+G  +P +V  +   +VRDP V+AW+L+++K
Sbjct: 105 SDDAAQTADEQTLIRRASKLQQQPFTQLPDGIAQPQKVSTVSTAFVRDPKVRAWVLKEAK 164

Query: 205 GICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKEL 264
           GICE CG NAPF   DG P+LEVHHV  L+  G+D   N VALCPNCH+  H S +    
Sbjct: 165 GICEGCGSNAPFE-VDGLPFLEVHHVKHLAQKGSDRISNAVALCPNCHQRCHRSSDRDAF 223

Query: 265 IEMLYVNINRLQK 277
            E LY  + RL +
Sbjct: 224 TEGLYAKVGRLAR 236


>UniRef50_Q2Y8M1 HNH nuclease n=1 Tax=Nitrosospira multiformis ATCC 25196
           RepID=Q2Y8M1_NITMU
          Length = 226

 Score =  147 bits (371), Expect = 4e-34,   Method: Composition-based stats.
 Identities = 61/142 (42%), Positives = 84/142 (59%), Gaps = 2/142 (1%)

Query: 138 ASIIRGELSELS-QPTDDESLLNMRVSKL-IKKTLSQPEGSRKPVEVERLQKVYVRDPMV 195
           A+ I   L ++S Q     +   + V +   +K L +P G+ +P           RDP V
Sbjct: 84  AARIEQLLEQISGQKAVPVAAFEIAVREAAEQKDLPKPSGNPRPKRRRISVAQLERDPNV 143

Query: 196 KAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHREL 255
           KAW+LQQ+ G CE+C K APF   DG+PYLE+H+V  L+ GGAD   N VALCPNCHRE+
Sbjct: 144 KAWVLQQAAGTCESCEKPAPFQGADGSPYLELHYVQGLADGGADAVSNAVALCPNCHREI 203

Query: 256 HYSKNAKELIEMLYVNINRLQK 277
           HY  NA+ +   LY  + RL++
Sbjct: 204 HYGANAQAVEAWLYDTVQRLER 225


>UniRef50_A6QD09 5-methylcytosine-specific restriction enzyme A n=2
           Tax=delta/epsilon subdivisions RepID=A6QD09_SULNB
          Length = 225

 Score =  147 bits (370), Expect = 5e-34,   Method: Composition-based stats.
 Identities = 53/127 (41%), Positives = 75/127 (59%), Gaps = 1/127 (0%)

Query: 150 QPTDDESLLNMRVSKLIKKTLS-QPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICE 208
           Q   +       V KL+ K L  +P+   +P   +     Y RDP + AW+L  +KGICE
Sbjct: 96  QALSEPVSFQAEVDKLVHKKLQDKPKAVLEPKRYDIAITKYDRDPQIVAWVLMNAKGICE 155

Query: 209 NCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEML 268
            C K APF  +DG P+LEVHH+  L+  G+D+  N +A+CPNCHRELHY +N   L+  +
Sbjct: 156 CCNKEAPFVKDDGVPFLEVHHLRRLADDGSDSITNAIAICPNCHRELHYGQNKDILLTTI 215

Query: 269 YVNINRL 275
           Y  ++RL
Sbjct: 216 YSQVSRL 222


>UniRef50_UPI00016A2859 HNH endonuclease n=1 Tax=Burkholderia thailandensis TXDOH
           RepID=UPI00016A2859
          Length = 214

 Score =  146 bits (368), Expect = 8e-34,   Method: Composition-based stats.
 Identities = 61/189 (32%), Positives = 95/189 (50%), Gaps = 9/189 (4%)

Query: 89  IGNSPRDIRLKMCGYQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSEL 148
           IG S +    +M          GR  IP       + + V G        ++I       
Sbjct: 34  IGRSEKSCEYRMRNISYVLELMGRDWIPGLPPATNVGVRVAGQIE-----ALIGKLEGRQ 88

Query: 149 SQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICE 208
             P   E++    ++++ K    +P+G++ P         +VRD  VKAW+L+++K  CE
Sbjct: 89  ELPRAAEAVT---IAEIRKTLDERPDGNKAPGTATSTTTSFVRDLKVKAWVLKRAKDNCE 145

Query: 209 NCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEML 268
            C + APF   +G P+LEVHH+  L+ GG+DT  N VA+CPNCHR LH+SK+A+   E +
Sbjct: 146 ACDQPAPFSGANG-PFLEVHHLRKLADGGSDTVTNAVAVCPNCHRRLHFSKDARAYRETI 204

Query: 269 YVNINRLQK 277
           Y  +  L +
Sbjct: 205 YEKVTELVR 213


>UniRef50_Q1YK78 Putative 5-methylcytosine-specific restriction enzyme n=1
           Tax=Aurantimonas manganoxydans SI85-9A1
           RepID=Q1YK78_MOBAS
          Length = 125

 Score =  146 bits (368), Expect = 9e-34,   Method: Composition-based stats.
 Identities = 53/118 (44%), Positives = 75/118 (63%), Gaps = 1/118 (0%)

Query: 157 LLNMRVSKL-IKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAP 215
            L  RVS+L  + T++ P+G  +P    R   V++RDP VKA++L+++ GICE C   AP
Sbjct: 2   ELERRVSRLSARATIAFPKGIVQPKHTTRTTIVFLRDPGVKAYVLRRAGGICEACDFPAP 61

Query: 216 FYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNIN 273
           F    G  +LEVHH+ PL+ GG+D   N VALCPNCHR +H++ +A +  E LY  I 
Sbjct: 62  FKTALGGDFLEVHHLKPLAEGGSDRAQNAVALCPNCHRAMHHASDAGQRTERLYAKIG 119


>UniRef50_B5EI94 HNH endonuclease n=1 Tax=Geobacter bemidjiensis Bem
           RepID=B5EI94_GEOBB
          Length = 233

 Score =  137 bits (345), Expect = 4e-31,   Method: Composition-based stats.
 Identities = 45/128 (35%), Positives = 68/128 (53%)

Query: 150 QPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICEN 209
           +PT +E  ++   S  I      P+G  +P         Y RD  V+A+++ ++KG CE 
Sbjct: 95  EPTMNEEKVHEFASNAINDLDEIPQGVAEPERSSHTTSSYARDHKVRAYVIARAKGTCEY 154

Query: 210 CGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLY 269
           CG+      N  + YLE HHVI L+  G DT DN +ALCP  H+E H+  N  E+ E + 
Sbjct: 155 CGELGFLMSNGKSYYLEAHHVIALADEGRDTPDNVIALCPKHHKEAHFGINRDEIEEEMM 214

Query: 270 VNINRLQK 277
           + ++ L K
Sbjct: 215 IFLSTLSK 222


>UniRef50_C4WNE8 Putative uncharacterized protein n=1 Tax=Ochrobactrum intermedium
           LMG 3301 RepID=C4WNE8_9RHIZ
          Length = 282

 Score =  135 bits (341), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 40/137 (29%), Positives = 64/137 (46%), Gaps = 2/137 (1%)

Query: 140 IIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWI 199
                L  + +  DDE  +       ++    Q  GSR+     R   +Y R   V+ ++
Sbjct: 143 FELRNLENIVEAVDDEQPVPAVDLAAMRDLARQAAGSREGKASTR--TIYERSRHVRDYV 200

Query: 200 LQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSK 259
           L ++ G CE C   APF   +G PYLE HH+  +S GG D     +ALCP CHR++H+ +
Sbjct: 201 LARANGHCEGCSCQAPFLRINGQPYLEPHHIRRVSDGGPDDPSYVIALCPTCHRKVHHGQ 260

Query: 260 NAKELIEMLYVNINRLQ 276
                 + L   +  ++
Sbjct: 261 GGATYNDTLLKKMPSIE 277


>UniRef50_C3FAM5 HNH nuclease n=4 Tax=Bacillus cereus group RepID=C3FAM5_BACTU
          Length = 350

 Score =  134 bits (337), Expect = 3e-30,   Method: Composition-based stats.
 Identities = 47/123 (38%), Positives = 69/123 (56%), Gaps = 1/123 (0%)

Query: 137 WASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVK 196
           +   +    ++  +   D  +   ++S    +     + +RKP  VE +   Y R+P V 
Sbjct: 228 YYQTLHALTNQEYENDLDIKVKQSQISNGSARKERLKKAARKPDVVEVVTTQYKRNPDVI 287

Query: 197 AWILQQSKGICENCGKNAPFYL-NDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHREL 255
           A +L+++ G CE C + APF    DG PYLEVHHVIPL+ GG D+ +N V LCPNCHR+ 
Sbjct: 288 AEVLERANGYCEECKQEAPFKRAKDGTPYLEVHHVIPLAQGGEDSVENAVGLCPNCHRKA 347

Query: 256 HYS 258
           HY 
Sbjct: 348 HYG 350


>UniRef50_D0Z3H8 HNH nuclease n=1 Tax=Photobacterium damselae subsp. damselae CIP
           102761 RepID=D0Z3H8_LISDA
          Length = 278

 Score =  134 bits (337), Expect = 4e-30,   Method: Composition-based stats.
 Identities = 48/119 (40%), Positives = 71/119 (59%), Gaps = 2/119 (1%)

Query: 141 IRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWIL 200
           I  E ++      ++S++        K+     + ++KP  + R+ K Y R+P + A  L
Sbjct: 161 IDYEQADYFTNF-EQSVIKSLQDNPKKRRQRIEKANKKPQLISRVVKDYQRNPDIVAEAL 219

Query: 201 QQSKGICENCGKNAPF-YLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258
            ++ GICE CG  APF   ++G PYLEVHH+IPLS GG D+ DN  +LCPNCHR+LH+ 
Sbjct: 220 IRAAGICEACGCQAPFNKKSNGEPYLEVHHLIPLSKGGEDSLDNVQSLCPNCHRKLHFG 278


>UniRef50_Q080H4 HNH endonuclease n=1 Tax=Shewanella frigidimarina NCIMB 400
           RepID=Q080H4_SHEFN
          Length = 309

 Score =  133 bits (334), Expect = 7e-30,   Method: Composition-based stats.
 Identities = 45/156 (28%), Positives = 73/156 (46%), Gaps = 5/156 (3%)

Query: 117 SGNRTKRILINVPGIYSDSFWASIIRGELS-----ELSQPTDDESLLNMRVSKLIKKTLS 171
           S N  K   I V  I SD F   +    ++     +L+   +      +   +L ++  +
Sbjct: 144 STNSAKESAILVGLIESDDFTVKLHDFLINIANFKQLATTGEINEATFISDDELWERICT 203

Query: 172 QPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVI 231
           +    + P +       Y R   VK + L+ + G C+ C    PF    G  +LEVHH+ 
Sbjct: 204 ENPKRKSPKKTTTETVGYERSEFVKEYALRHANGKCQLCNNAGPFATKSGRNFLEVHHID 263

Query: 232 PLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEM 267
            LS GG D  +N V LCPNCHR++H   +AK++ ++
Sbjct: 264 WLSKGGLDMPENVVGLCPNCHRKMHNINDAKDIKKL 299


>UniRef50_C0WRI9 Possible HNH endonuclease n=1 Tax=Lactobacillus buchneri ATCC 11577
           RepID=C0WRI9_LACBU
          Length = 193

 Score =  131 bits (330), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 42/127 (33%), Positives = 70/127 (55%), Gaps = 1/127 (0%)

Query: 140 IIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVE-VERLQKVYVRDPMVKAW 198
           I   E+   S+   ++++  M + KLI+   +  +G        E    ++VR+   +  
Sbjct: 49  IANKEVLHQSEIKQEQAVKKMPIKKLIESVKTHEQGKTAKTSCREVTTTMFVRNANNRHL 108

Query: 199 ILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258
            L  SKG+C+ CG+ APF    G PYLEVHH+   S GG D  +N +A+CPNCHR++H  
Sbjct: 109 ALYFSKGVCQLCGEPAPFKDKTGQPYLEVHHIDWFSQGGKDVIENEIAICPNCHRKMHII 168

Query: 259 KNAKELI 265
           ++  +++
Sbjct: 169 QDPNDVL 175


>UniRef50_A2SMM5 Putative uncharacterized protein n=1 Tax=Methylibium petroleiphilum
           PM1 RepID=A2SMM5_METPP
          Length = 220

 Score =  130 bits (327), Expect = 5e-29,   Method: Composition-based stats.
 Identities = 48/120 (40%), Positives = 67/120 (55%), Gaps = 2/120 (1%)

Query: 140 IIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWI 199
               +L EL    + +     ++S   ++ + +  G  KP  V     V++R+P V A +
Sbjct: 102 TAMPDLLELHAEFERQVNECAQMSSAERRNMFET-GQAKPERVIVQTTVFMRNPAVAAEV 160

Query: 200 LQQSKGICENCGKNAPFYL-NDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258
           L ++ G CE C ++APF    DG PYLEVHH  PLS GG DT  N +ALCPNCHR  HY+
Sbjct: 161 LLRANGHCELCRQSAPFKRRKDGTPYLEVHHRKPLSDGGNDTVQNAIALCPNCHRRAHYA 220


>UniRef50_Q3K870 Putative 5-methylcytosine-specific restriction enzyme n=1
           Tax=Pseudomonas fluorescens Pf0-1 RepID=Q3K870_PSEPF
          Length = 237

 Score =  130 bits (326), Expect = 6e-29,   Method: Composition-based stats.
 Identities = 47/104 (45%), Positives = 61/104 (58%)

Query: 173 PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIP 232
           P G   P +         R   VK W+L++S+GICE CG+ APF   DG P+LEVHH+  
Sbjct: 132 PPGVLNPKQTSATVVRLSRKLNVKKWVLKRSQGICEGCGQKAPFQDADGKPFLEVHHLKH 191

Query: 233 LSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQ 276
           L +GG D T N VALCPNCHR  HYS + +E     Y ++  L+
Sbjct: 192 LVNGGTDRTSNAVALCPNCHRRCHYSSDKEEFTAKFYRSVEGLE 235


>UniRef50_Q0BZ66 Conserved domain protein n=1 Tax=Hyphomonas neptunium ATCC 15444
           RepID=Q0BZ66_HYPNA
          Length = 343

 Score =  129 bits (324), Expect = 1e-28,   Method: Composition-based stats.
 Identities = 46/139 (33%), Positives = 68/139 (48%), Gaps = 5/139 (3%)

Query: 139 SIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAW 198
           ++   E  E  +   D S+ ++R S     T  +   +  P E  R+ +   R   +KA+
Sbjct: 206 AVADSETDEEIEDQPDTSIDDLRTSAYEAATAVR---NSNPKEARRVYR--QRSAKIKAY 260

Query: 199 ILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258
           IL ++ G+CE  G+ APF    G+PYLEVHH   LS  G D      A+ P  HRE+H+ 
Sbjct: 261 ILARAGGVCELTGEKAPFLTKSGHPYLEVHHTQRLSDDGLDHPRWVAAISPTAHREIHFG 320

Query: 259 KNAKELIEMLYVNINRLQK 277
           +   EL E L   I   +K
Sbjct: 321 ERGDELNERLKEIIAEKEK 339


>UniRef50_C4SUH5 Restriction endonuclease n=1 Tax=Yersinia frederiksenii ATCC 33641
           RepID=C4SUH5_YERFR
          Length = 238

 Score =  129 bits (323), Expect = 1e-28,   Method: Composition-based stats.
 Identities = 53/164 (32%), Positives = 82/164 (50%), Gaps = 11/164 (6%)

Query: 107 FSRTGRKEIPSGNR---TKRILI--NVPGIYSDSFWASIIRGELS---ELSQPTDDESLL 158
           F+RT R+   + +R     R+    NV  +Y  +        E S    L++P   E   
Sbjct: 66  FNRTARRTDDATHRHHEYDRLFKRGNVFEVYDSALHGVFEIYEASDGKWLTRPVKSEFEK 125

Query: 159 NMRVSKLIKKTLSQPE---GSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAP 215
            +  +  +     + +    +  P  V      + R+P+V A +L  + G C++C ++AP
Sbjct: 126 AIETASQLTSEQRREKLATANTTPERVIIKSYTFKRNPLVVAEVLALAGGKCQSCLRDAP 185

Query: 216 FYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSK 259
           F   DG PYLEVHHV  L++GG D+ +N +ALCPNCHRE HY  
Sbjct: 186 FKREDGRPYLEVHHVEWLANGGEDSVENAIALCPNCHREAHYGA 229


>UniRef50_A3JQK6 HNH nuclease n=1 Tax=Rhodobacterales bacterium HTCC2150
           RepID=A3JQK6_9RHOB
          Length = 371

 Score =  128 bits (322), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 48/131 (36%), Positives = 70/131 (53%), Gaps = 8/131 (6%)

Query: 137 WASIIRGE--LSELSQPTDDESLLNMRVSKLIKKTLSQPEGS-----RKPVEVERLQKVY 189
           W +++     LS+L      E+ L  +V K +K      +       + P + +    ++
Sbjct: 236 WFTLVEWSDGLSDLQSVAAAETSLVEQVQKSLKLDPKARQKRLADAPKLPEKQKATTTIF 295

Query: 190 VRDPMVKAWILQQSKGICENCGKNAPF-YLNDGNPYLEVHHVIPLSSGGADTTDNCVALC 248
            R+P V A +L ++ G CE C ++APF   +DG PYLEVHH IPL+  G D+ DN VALC
Sbjct: 296 KRNPDVIAEVLFRANGTCEGCRQSAPFDRRSDGTPYLEVHHKIPLAKDGHDSVDNAVALC 355

Query: 249 PNCHRELHYSK 259
           PNCHR  H   
Sbjct: 356 PNCHRREHSGP 366


>UniRef50_D0KA86 HNH endonuclease n=2 Tax=Enterobacteriaceae RepID=D0KA86_PECWW
          Length = 240

 Score =  128 bits (322), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 52/149 (34%), Positives = 77/149 (51%), Gaps = 10/149 (6%)

Query: 120 RTKRILINVPGIYS-----DSFWASIIRGELSELSQPTDDESLLNMRVSKLI----KKTL 170
           R  R  I  P I+      +  +      E+  + +    ++   + V K      K+  
Sbjct: 92  RGDRYEIYQPSIHGVWELYEDIYGKWCFREIETIDEAKRLQAEFEIEVRKASQLTSKERK 151

Query: 171 SQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFY-LNDGNPYLEVHH 229
                S  P   E + K++VR+P V A +L +++G CE C +NAPF    DG PYLEVHH
Sbjct: 152 QHLAVSNFPEMKEVITKIFVRNPYVVAEVLHRAQGKCELCKRNAPFLRGKDGTPYLEVHH 211

Query: 230 VIPLSSGGADTTDNCVALCPNCHRELHYS 258
            +PLS GG DT +N +A+CPNCHR+ H+ 
Sbjct: 212 CVPLSQGGEDTVENAIAVCPNCHRQAHFG 240


>UniRef50_D2C2V7 HNH endonuclease n=1 Tax=Dickeya dadantii Ech586 RepID=D2C2V7_DICD5
          Length = 245

 Score =  128 bits (321), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 55/130 (42%), Positives = 71/130 (54%), Gaps = 9/130 (6%)

Query: 140 IIRGELSELSQPTDDESL---LNMRVSKLIKKTLSQPEGS-----RKPVEVERLQKVYVR 191
           II    SELS+    E+L    N++V+K I       +       + P +     + ++R
Sbjct: 115 IIEFYESELSKTDSFENLTTEFNIQVNKSIADNQRSRQERLSTSPKYPQKKSLQIEFFIR 174

Query: 192 DPMVKAWILQQSKGICENCGKNAPFYLN-DGNPYLEVHHVIPLSSGGADTTDNCVALCPN 250
           +P V A +L ++ G CE C  NAPF    D  PYLEVHH  PLS GGADT DN +ALCPN
Sbjct: 175 NPDVVAEVLLRANGKCERCCSNAPFLRKKDNTPYLEVHHKTPLSEGGADTVDNAIALCPN 234

Query: 251 CHRELHYSKN 260
           CHR LHY   
Sbjct: 235 CHRYLHYGDK 244


>UniRef50_A4SC99 HNH endonuclease n=1 Tax=Chlorobium phaeovibrioides DSM 265
           RepID=A4SC99_PROVI
          Length = 222

 Score =  128 bits (321), Expect = 3e-28,   Method: Composition-based stats.
 Identities = 46/121 (38%), Positives = 67/121 (55%), Gaps = 10/121 (8%)

Query: 139 SIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAW 198
           ++I  E +E+++   D S+   R  +++          ++P         Y R+P +   
Sbjct: 111 ALIETETAEIAKSRTDTSV--ARNERILN-------AEKRPKRQRVYSYTYQRNPDIVVE 161

Query: 199 ILQQSKGICENCGKNAPFYL-NDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHY 257
            L +++G CENC   APF   +DG P+LEVHH+  LS GG DT +N VALCPNCHRE HY
Sbjct: 162 ALHRAEGFCENCKNPAPFKRASDGTPFLEVHHIRSLSDGGEDTLENVVALCPNCHREKHY 221

Query: 258 S 258
            
Sbjct: 222 G 222


>UniRef50_C0N619 HNH endonuclease domain protein n=1 Tax=Methylophaga thiooxidans
           DMS010 RepID=C0N619_9GAMM
          Length = 274

 Score =  127 bits (318), Expect = 6e-28,   Method: Composition-based stats.
 Identities = 43/124 (34%), Positives = 66/124 (53%), Gaps = 8/124 (6%)

Query: 154 DESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN 213
            +SLL +R + L K + ++          ER Q  Y R   ++ ++ +++ G CE C   
Sbjct: 156 KKSLLELREAALEKPSHTKNAS-------ERRQSAYYRSKALRLYVRKRAGGKCEACAVP 208

Query: 214 APFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNIN 273
           APF    G PY+E HH+  ++ GG D   N + LCPNCHR  HY+KN +E  + L   + 
Sbjct: 209 APFESRKG-PYIECHHLHRVADGGPDHPMNVIGLCPNCHRRAHYAKNFREFNDSLKPVVR 267

Query: 274 RLQK 277
            L+K
Sbjct: 268 ELEK 271


>UniRef50_C7HJ98 HNH endonuclease n=1 Tax=Clostridium thermocellum DSM 2360
           RepID=C7HJ98_CLOTM
          Length = 276

 Score =  126 bits (316), Expect = 8e-28,   Method: Composition-based stats.
 Identities = 46/134 (34%), Positives = 71/134 (52%), Gaps = 1/134 (0%)

Query: 144 ELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQS 203
           E S +    + E +        +K+   Q E S K    +    V++RD  V  +  +++
Sbjct: 144 EESFIKYIKEKEKVAEKLTLNELKERAEQNE-SDKVSSRKVTSNVFIRDAFVAEYAKRRA 202

Query: 204 KGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKE 263
            G+C+ CG+ APF   +G PYLE HH+  LS GG+DT +N VALCPNCHR++H    + +
Sbjct: 203 NGVCQLCGQKAPFNNKEGIPYLECHHIEWLSEGGSDTIENTVALCPNCHRKMHILNLSSD 262

Query: 264 LIEMLYVNINRLQK 277
             ++      RL K
Sbjct: 263 KEKLKIQAKIRLSK 276


>UniRef50_A8ZWC1 HNH endonuclease n=1 Tax=Desulfococcus oleovorans Hxd3
           RepID=A8ZWC1_DESOH
          Length = 303

 Score =  124 bits (311), Expect = 3e-27,   Method: Composition-based stats.
 Identities = 40/135 (29%), Positives = 75/135 (55%), Gaps = 4/135 (2%)

Query: 140 IIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWI 199
           I++    +L + ++++    +  +  I    + P G  +P ++ R+   Y RDP +++++
Sbjct: 172 IVKKYSIDLLKSSENQ----LPSTDAINDLNAYPPGISEPEKISRMSPSYSRDPKIRSFV 227

Query: 200 LQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSK 259
           ++++KG CE CG+      +  N YLE HH+I L+  G DT +N +ALCP  HRE H+  
Sbjct: 228 IKRAKGRCEYCGEQGFLMSDGQNYYLEAHHIIALADEGEDTVENVIALCPKHHREAHFGA 287

Query: 260 NAKELIEMLYVNINR 274
           N ++L   +   I +
Sbjct: 288 NKEKLEVEMAKLIKQ 302


>UniRef50_C6ANH6 HNH nuclease n=1 Tax=Aggregatibacter aphrophilus NJ8700
           RepID=C6ANH6_AGGAN
          Length = 194

 Score =  123 bits (308), Expect = 8e-27,   Method: Composition-based stats.
 Identities = 41/110 (37%), Positives = 59/110 (53%), Gaps = 1/110 (0%)

Query: 150 QPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICEN 209
           + +  E ++         +       S+ P++       + R+P V A +L ++ G CE 
Sbjct: 85  ESSFIEQIIESLNDTSENRKRRLKSQSKHPIKKIIEVLQFQRNPDVVAEVLVRANGYCEK 144

Query: 210 CGKNAPFYLNDG-NPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258
           C K APF       PYLEVHH+IPLS  G DT +NC+ALCPNCHR+ H+ 
Sbjct: 145 CKKPAPFIRKANLQPYLEVHHIIPLSKDGEDTVENCMALCPNCHRQEHFG 194


>UniRef50_C3C627 Restriction endonuclease n=7 Tax=Bacillus RepID=C3C627_BACTU
          Length = 333

 Score =  122 bits (307), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 42/117 (35%), Positives = 61/117 (52%), Gaps = 2/117 (1%)

Query: 153 DDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKV--YVRDPMVKAWILQQSKGICENC 210
             +   N +  KL  + L +      P   +R  K   Y R+  V  +  +++ GICE C
Sbjct: 204 SKQVKENKKARKLDYQKLKERAKKATPSSNKRYTKTETYQRNEFVAEFSKRRANGICELC 263

Query: 211 GKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEM 267
            + APF   +GNPYLE HHV  LS GG DT  N V +C NCHR LH   +  +++++
Sbjct: 264 EQQAPFEDKEGNPYLESHHVEWLSEGGEDTIYNTVGVCANCHRRLHVLNDENDVMKL 320


>UniRef50_C9PPM2 5-methylcytosine-specific restriction enzyme A n=1 Tax=Pasteurella
           dagmatis ATCC 43325 RepID=C9PPM2_9PAST
          Length = 200

 Score =  122 bits (305), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 47/134 (35%), Positives = 70/134 (52%), Gaps = 7/134 (5%)

Query: 135 SFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGS------RKPVEVERLQKV 188
           +     I  + + L    + +S  + +V K +  +  + +        +KP       + 
Sbjct: 67  NLGFEAIDIQTNALYPNQNFDSEFDKKVKKALHDSPEKRQKRLDRKKIKKPSYSFVKIRQ 126

Query: 189 YVRDPMVKAWILQQSKGICENCGKNAPFYLN-DGNPYLEVHHVIPLSSGGADTTDNCVAL 247
           + RDP V A +L Q+ G+C  C K APF    D  PYLEVHH IPLS  G D+  NC+AL
Sbjct: 127 FHRDPDVVAEVLYQANGVCGACKKPAPFNRKVDNMPYLEVHHKIPLSQNGDDSVSNCIAL 186

Query: 248 CPNCHRELHYSKNA 261
           CPNCHR++H+  N+
Sbjct: 187 CPNCHRKIHFGNNS 200


>UniRef50_Q312Y0 HNH nuclease n=1 Tax=Desulfovibrio desulfuricans subsp.
           desulfuricans str. G20 RepID=Q312Y0_DESDG
          Length = 260

 Score =  122 bits (305), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 45/85 (52%), Positives = 53/85 (62%), Gaps = 1/85 (1%)

Query: 179 PVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPF-YLNDGNPYLEVHHVIPLSSGG 237
           P    R Q V+ R P+V A +L ++ G CE CG  APF    D  PYLEVHHV PL+ GG
Sbjct: 168 PGMTVREQAVFRRSPVVAARVLLRAGGFCECCGAPAPFVSRADNLPYLEVHHVRPLAEGG 227

Query: 238 ADTTDNCVALCPNCHRELHYSKNAK 262
           ADT  NC+ALCPNCHR+ HY     
Sbjct: 228 ADTPANCMALCPNCHRQFHYGIKPP 252


>UniRef50_A6VSV6 HNH endonuclease n=1 Tax=Marinomonas sp. MWYL1 RepID=A6VSV6_MARMS
          Length = 240

 Score =  120 bits (301), Expect = 5e-26,   Method: Composition-based stats.
 Identities = 41/83 (49%), Positives = 53/83 (63%), Gaps = 1/83 (1%)

Query: 177 RKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYL-NDGNPYLEVHHVIPLSS 235
           + P  +     VY R+P V    L+++ G+CE CGK APF    DG+PYLEVHH+  L+ 
Sbjct: 158 KIPNTITVSATVYQRNPDVITETLERAAGVCERCGKGAPFIRSKDGSPYLEVHHIQRLAD 217

Query: 236 GGADTTDNCVALCPNCHRELHYS 258
            G DT +N  ALCPNCHRELH+ 
Sbjct: 218 NGPDTLENTKALCPNCHRELHFG 240


>UniRef50_Q1QEV2 HNH endonuclease n=5 Tax=Gammaproteobacteria RepID=Q1QEV2_PSYCK
          Length = 282

 Score =  120 bits (300), Expect = 7e-26,   Method: Composition-based stats.
 Identities = 44/130 (33%), Positives = 66/130 (50%), Gaps = 8/130 (6%)

Query: 147 ELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGI 206
            +++P+  +SL  +R   L                 E++Q +  R   +K +  +++ GI
Sbjct: 156 YVTKPSKGKSLQQLREIALSSTP-------THASTQEKIQSIQNRSTAIKLYAKKRANGI 208

Query: 207 CENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIE 266
           CE C + APF    G PYLEVHH+  L+ GGAD   N +ALCP CHR+ HYS N  E   
Sbjct: 209 CEGCNEIAPFETKSG-PYLEVHHLTRLADGGADLPQNVIALCPTCHRKAHYSLNHLEFNN 267

Query: 267 MLYVNINRLQ 276
            L   +  ++
Sbjct: 268 QLINKVAAIE 277


>UniRef50_C2KXT9 Putative uncharacterized protein n=1 Tax=Oribacterium sinus F0268
           RepID=C2KXT9_9FIRM
          Length = 324

 Score =  117 bits (293), Expect = 5e-25,   Method: Composition-based stats.
 Identities = 39/117 (33%), Positives = 66/117 (56%)

Query: 151 PTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENC 210
           PT D+ L   +      K   +    + P +     +V  R  +V + + +++ G+C+ C
Sbjct: 201 PTVDKGLAKKKSKLSQLKKDLKDFDKQHPKKKLTEVEVVQRSSLVSSIVKERAAGVCQLC 260

Query: 211 GKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEM 267
            K APFY   G  YLE HHV+ ++ GGAD  +N VALCPNCHR++H   +++++ ++
Sbjct: 261 NKPAPFYNKSGEAYLECHHVVWIAKGGADEVNNAVALCPNCHRKMHILDDSEDVEKL 317


>UniRef50_C9XQW3 Putative uncharacterized protein n=2 Tax=Clostridium difficile
           RepID=C9XQW3_CLODC
          Length = 375

 Score =  116 bits (290), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 44/143 (30%), Positives = 66/143 (46%), Gaps = 13/143 (9%)

Query: 136 FWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMV 195
           F A I    L E+SQ    ++ LN+    +  +T  + EG  K V      K Y R+P  
Sbjct: 238 FTAEIEDDVLEEISQ----DNPLNINTINIELETEIRKEGKVKYV----YGKQYERNPRN 289

Query: 196 KAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSSGGADTTDN----CVALCPN 250
           +   ++     C  CG +    Y + G  Y+E+HH+ PLSS G ++  N     V +C N
Sbjct: 290 RIEAIKYHGTKCIVCGFDFEKTYGDRGKGYIEIHHIKPLSSVGEESNINPKTDLVPICSN 349

Query: 251 CHRELHYSKNAKELIEMLYVNIN 273
           CHR +H  K+    I+ L   I 
Sbjct: 350 CHRMIHRKKDNVLSIDDLKQIIK 372


>UniRef50_C2ECC9 Recombinase n=1 Tax=Lactobacillus ruminis ATCC 25644
           RepID=C2ECC9_9LACO
          Length = 270

 Score =  115 bits (289), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 37/144 (25%), Positives = 62/144 (43%), Gaps = 11/144 (7%)

Query: 135 SFWASIIRGELSELSQ-PTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDP 193
           +F+++ I G L  L Q    +   +    S+  K  L +    + PV+   LQ  Y R+P
Sbjct: 105 NFYSATINGYLDYLDQLKIVNAGEIKESPSERYKIKLLKKPVRKSPVQTTILQ--YPRNP 162

Query: 194 MVKAWILQQSKGICENCGKNAPFYLN-DGNPYLEVHHVIPLSSG-----GADTTDNCVAL 247
                   +S   C     +  F    D   ++E HH+IP+          D  DN + L
Sbjct: 163 HEMLAAKHRSGWKCCYDSSHETFISENDHKNFVEGHHLIPMQHQCDFEYTIDFADNIIPL 222

Query: 248 CPNCHRELHYS--KNAKELIEMLY 269
           CP CHR +H++  ++   ++E  Y
Sbjct: 223 CPTCHRRIHFAIKQDRNRMLEKFY 246


>UniRef50_B4S2Y7 HNH nuclease n=2 Tax=Proteobacteria RepID=B4S2Y7_ALTMD
          Length = 116

 Score =  115 bits (289), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 43/115 (37%), Positives = 65/115 (56%), Gaps = 2/115 (1%)

Query: 145 LSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSK 204
           LS++ +  + + +   + S   ++   Q    + P        V  R+P V A +L ++K
Sbjct: 3   LSDIDKDFEKDVVRAQQRSAEERQRRLQK-APKIPQTSIVEVSVLQRNPDVVAEVLFRAK 61

Query: 205 GICENCGKNAPF-YLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258
           GIC +C   APF    DG+PYLEVHH+  L+ GG DT +N +ALCPNCHR+ H+ 
Sbjct: 62  GICGSCKNPAPFSRRKDGSPYLEVHHIQQLAHGGEDTLENAIALCPNCHRQKHFG 116


>UniRef50_D2S1X8 HNH endonuclease n=1 Tax=Haloterrigena turkmenica DSM 5511
           RepID=D2S1X8_9EURY
          Length = 84

 Score =  107 bits (268), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 34/81 (41%), Positives = 48/81 (59%)

Query: 196 KAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHREL 255
           + + LQ + G+C+ C  +APF  +D   +LEVHH+   S+GGAD   N +ALCPNCHR +
Sbjct: 2   RKYALQVADGVCQGCSDDAPFLTDDRESFLEVHHLRRRSNGGADHPKNVIALCPNCHRRV 61

Query: 256 HYSKNAKELIEMLYVNINRLQ 276
           H+ +N  E  E L      L 
Sbjct: 62  HHGRNGDEFNEDLIDKAEELH 82


>UniRef50_D1NJY2 Transcriptional regulator, XRE family n=1 Tax=Clostridium
           thermocellum JW20 RepID=D1NJY2_CLOTM
          Length = 446

 Score =  107 bits (268), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 43/172 (25%), Positives = 74/172 (43%), Gaps = 23/172 (13%)

Query: 118 GNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEG-- 175
           GNRT            + F+  ++  +   +    + +S +  +  K         EG  
Sbjct: 269 GNRT-----------PEQFYDYLVAKKEGWVDSEHEVDSTMQTQEEKSEDNNFDDEEGPI 317

Query: 176 -SRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLN-DGNPYLEVHHVIPL 233
             + PV        ++R+P V    L++++  CE    +  F       PY+E HH+IP+
Sbjct: 318 DRQDPVVDREGNIRFLRNPKVAIQALKKAQYKCEINDAHETFIAKSSNKPYVESHHLIPI 377

Query: 234 SSG-----GADTTDNCVALCPNCHRELHYSKN--AKELIEMLYVNI-NRLQK 277
           S+        D T N  +LCPNCHR +H + +   +E++  LY     RL+K
Sbjct: 378 SNSAMFGFSIDITANICSLCPNCHRAIHSATDEVKREMLTKLYEKRKERLEK 429


>UniRef50_C4L1L5 HNH endonuclease n=2 Tax=Bacillales RepID=C4L1L5_EXISA
          Length = 346

 Score =  107 bits (268), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 39/139 (28%), Positives = 59/139 (42%), Gaps = 12/139 (8%)

Query: 141 IRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWIL 200
           + GEL +      D+ L     +  + ++L   EG RK V V      Y R+P+ +   +
Sbjct: 204 LMGELKDYITSFFDKDLTAEYYADEVAESLE--EGKRKVVTVN----TYERNPLARKRCM 257

Query: 201 QQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSSGG----ADTTDNCVALCPNCHREL 255
           +     C+ C  N    Y   G  ++ VHH+ PL   G     D   +   +CPNCH  L
Sbjct: 258 EYYGVSCQVCQINFEKIYGEVGRDFIHVHHIKPLHEIGQNYVVDPITDLRPVCPNCHAML 317

Query: 256 HYSKNAKEL-IEMLYVNIN 273
           H  +  + L IE L   I 
Sbjct: 318 HRKEGGEYLTIEQLKNRIK 336


>UniRef50_Q9L0M9 Putative uncharacterized protein SCO4631 n=3 Tax=Streptomyces
           RepID=Q9L0M9_STRCO
          Length = 560

 Score =  107 bits (267), Expect = 4e-22,   Method: Composition-based stats.
 Identities = 39/127 (30%), Positives = 56/127 (44%), Gaps = 3/127 (2%)

Query: 153 DDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICEN--C 210
           D     +    +L +K  +  E   +  +     K YVRDP  +  +L++ +  CEN  C
Sbjct: 431 DGTESDDEAYRRLAQKAEANAERRGQLKKPTVADK-YVRDPSARGAVLKRCQKRCENPEC 489

Query: 211 GKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYV 270
             +       G P L+V HV  L+ GG D   N +ALCPNCH    Y  N   L  +L  
Sbjct: 490 AGHPTELTKAGLPILQVDHVNDLAKGGPDVPWNMIALCPNCHALKTYGANKVRLQRLLAA 549

Query: 271 NINRLQK 277
              RL +
Sbjct: 550 TARRLHE 556


>UniRef50_A8R8M0 Putative uncharacterized protein n=1 Tax=Eubacterium dolichum DSM
           3991 RepID=A8R8M0_9FIRM
          Length = 508

 Score =  105 bits (262), Expect = 2e-21,   Method: Composition-based stats.
 Identities = 45/156 (28%), Positives = 72/156 (46%), Gaps = 10/156 (6%)

Query: 132 YSDSFWASIIRGELSELSQPTDDE---SLLNMRVSKLIKKTLSQPE-GSRKPVEVERLQK 187
           Y D++       ++S+ +   DDE    + N R +       ++     ++P        
Sbjct: 336 YIDAYTKEKYEKDVSKENLTQDDELNEEITNHRFNGDETFEYTKEVVKKQEPKISFHGVL 395

Query: 188 VYVRDPMVKAWILQQSKGICENCGKNAPFYLN-DGNPYLEVHHVIPLSSG-----GADTT 241
           +Y R+       +  SK  CE   K+  F    DG PY+E HH+IP+S         D  
Sbjct: 396 IYKRERKRANNAIIHSKHQCEIDAKHISFKRKNDGFPYMEAHHLIPMSKQDLFEYSLDVE 455

Query: 242 DNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277
           +N V+LC  CHRE+H+ +NA  LI+ LY +  +L K
Sbjct: 456 ENIVSLCSQCHREIHHGENADALIKKLYNDRKKLLK 491


>UniRef50_A3US95 Putative restriction endonuclease n=1 Tax=Vibrio splendidus 12B01
           RepID=A3US95_VIBSP
          Length = 259

 Score =  104 bits (260), Expect = 2e-21,   Method: Composition-based stats.
 Identities = 36/119 (30%), Positives = 56/119 (47%), Gaps = 5/119 (4%)

Query: 146 SELSQPTDDESLLNMRVSKLIKKTLSQ-----PEGSRKPVEVERLQKVYVRDPMVKAWIL 200
               +  D +S+ ++RV K  K T+ +      +G +     ++    Y R+  V     
Sbjct: 139 ERQVKKEDRDSVESVRVRKAKKLTVEELQALAAKGRKTATRYQQKSTSYERNIWVAELAK 198

Query: 201 QQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSK 259
           + +KG C+ C K APF    G PYLE HH+  LS GG DT +N   + P   +E  +S 
Sbjct: 199 RLAKGQCQLCLKPAPFKNTKGEPYLETHHIAWLSKGGEDTAENTSRIVPQLPQENAHSS 257


>UniRef50_C9BZK6 Restriction endonuclease (Fragment) n=4 Tax=Firmicutes
           RepID=C9BZK6_ENTFC
          Length = 96

 Score =  104 bits (260), Expect = 3e-21,   Method: Composition-based stats.
 Identities = 35/86 (40%), Positives = 51/86 (59%), Gaps = 1/86 (1%)

Query: 189 YVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALC 248
           Y R+P V  ++ + +KGIC+ C +  PF   DG PYL  HH+  LS GG D  +NC+ALC
Sbjct: 4   YKRNPFVSEYVKRLAKGICQLCQEKGPFI-KDGVPYLHCHHIEYLSQGGKDVIENCIALC 62

Query: 249 PNCHRELHYSKNAKELIEMLYVNINR 274
           PNCH  +H  +   +  ++L +   R
Sbjct: 63  PNCHARIHELELPDDKEKLLKIVEKR 88


>UniRef50_A9F818 Putative restriction endonuclease n=1 Tax=Phaeobacter gallaeciensis
           2.10 RepID=A9F818_9RHOB
          Length = 220

 Score =  104 bits (259), Expect = 4e-21,   Method: Composition-based stats.
 Identities = 34/90 (37%), Positives = 46/90 (51%), Gaps = 1/90 (1%)

Query: 173 PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIP 232
              S K         V+VR+      + Q + G+C+ C K   F    G+ +LEVHH   
Sbjct: 131 AAKSAKAEVNSVTGTVFVRNSEFSRRVRQAANGVCDAC-KGKTFQTQSGDWFLEVHHKKW 189

Query: 233 LSSGGADTTDNCVALCPNCHRELHYSKNAK 262
           LS GG DT +N VALCPNCHR+ H+    +
Sbjct: 190 LSEGGTDTIENMVALCPNCHRQEHFGSTRR 219


>UniRef50_C0QGN0 Putative 5-methylcytosine-specific restriction enzyme A n=1
           Tax=Desulfobacterium autotrophicum HRM2
           RepID=C0QGN0_DESAH
          Length = 375

 Score =  104 bits (259), Expect = 4e-21,   Method: Composition-based stats.
 Identities = 58/262 (22%), Positives = 107/262 (40%), Gaps = 29/262 (11%)

Query: 22  GVYGLILESWGPGDRNKDYNIALDYIIERLVDSGVSQVVVYLASSSVRKHMHSLDERKIH 81
           G YG+  ES      + D    +  + E+    G+ +++ +  +    +H+ S +  +  
Sbjct: 137 GGYGVSQESKWSKVNDDDLVYVIQNVYEKFEFCGIYRILSHYKN----EHIGSKNHFRFQ 192

Query: 82  PGEYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEIPSG-NRTKRILINVPGIYSDSFWASI 140
             +   LI  +P DI   +CG      R  + E P+  +  KR   +    + +   + +
Sbjct: 193 LEDITCLI--NPIDINEDLCG-----RRLPQLEKPANWSNFKRHFCSQGATFRNPLSSEV 245

Query: 141 IRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWIL 200
            +     L     D+            + +   EG+++ V + +    Y RD   +   +
Sbjct: 246 FQV----LDSLLPDKRPFQFAEEISENEEMLFFEGAKQTVTINK----YERDHNARKACI 297

Query: 201 QQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSSGGADTTDN----CVALCPNCHREL 255
           +     C+ CG +    Y   G  Y+ VHH+IPLS  G + + N     + +CPNCH  L
Sbjct: 298 EYHGYNCKVCGFDFEKTYGELGRNYIHVHHLIPLSKIGKEYSINPQTDLIPVCPNCHAML 357

Query: 256 HYSKNAKELIEMLYVNINRLQK 277
           H S+N  +    LY     +QK
Sbjct: 358 HKSENPND----LYSLKKMIQK 375


>UniRef50_C4L074 HNH endonuclease n=1 Tax=Exiguobacterium sp. AT1b
           RepID=C4L074_EXISA
          Length = 272

 Score =  104 bits (258), Expect = 5e-21,   Method: Composition-based stats.
 Identities = 35/108 (32%), Positives = 50/108 (46%), Gaps = 4/108 (3%)

Query: 165 LIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPY 224
           ++K+ L +  GS   +   R Q++  R   V   IL ++   CE CG  +PF   DG  Y
Sbjct: 158 IVKQNLQKVSGSSTAI---RKQQIRERSAAVYYSILARANNHCEACGSPSPFETEDG-AY 213

Query: 225 LEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNI 272
           LE+H +   S           A+CPNCH  LH  K+  +  E L   I
Sbjct: 214 LELHSLYSHSDQIILLPGLGAAVCPNCHMRLHKGKDRSQYNEQLQHKI 261


>UniRef50_A3WFM1 5-methylcytosine-specific restriction enzyme A n=1
           Tax=Erythrobacter sp. NAP1 RepID=A3WFM1_9SPHN
          Length = 288

 Score =  102 bits (254), Expect = 1e-20,   Method: Composition-based stats.
 Identities = 42/161 (26%), Positives = 69/161 (42%), Gaps = 29/161 (18%)

Query: 136 FWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEG----------------SRKP 179
           FW    RG+   L Q TD      + + ++ K  L+  +G                 + P
Sbjct: 114 FWGVFERGDDIWLFQATD------VFMDRIRKHGLASEDGGSILEPEVDDYQSEINQKAP 167

Query: 180 VEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPF-YLNDGNPYLEVHHVIPLSSG-- 236
            ++   QK + RDP V A  L+ +   CE   +   F   + G P++E HH+IP+ +   
Sbjct: 168 SQITSTQKAWSRDPKVAAEALKNASFECELYPELPTFTSRSTGYPFMEAHHLIPMKAQAD 227

Query: 237 ---GADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINR 274
                D  DN   L P  HR+LH ++   ++I+ L   I +
Sbjct: 228 FDVSLDVVDNICCLSPFAHRKLHMAE-FDDIIDDLERLIAK 267


>UniRef50_Q0KFQ5 Predicted restriction endonuclease n=1 Tax=Ralstonia eutropha H16
           RepID=Q0KFQ5_RALEH
          Length = 371

 Score =  101 bits (252), Expect = 2e-20,   Method: Composition-based stats.
 Identities = 36/108 (33%), Positives = 53/108 (49%), Gaps = 9/108 (8%)

Query: 179 PVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGN-PYLEVHHVIPLSSG- 236
           P         Y RDP+V A  ++ ++  CE   ++  F  +  N PY+E HH+IPLS   
Sbjct: 241 PKRGNGGSWKYPRDPLVAAEAVKSAEYRCELFPEHQTFKSSSKNVPYVEAHHLIPLSRQA 300

Query: 237 ----GADTTDNCVALCPNCHRELHYS---KNAKELIEMLYVNINRLQK 277
                 D T N +ALCP CH+ LH+    +    L  +L    +RLQ+
Sbjct: 301 DFQFSLDITANIIALCPTCHQRLHHGHASERRSPLRRLLSQRKDRLQE 348


>UniRef50_UPI0001A457FB putative 5-methylcytosine-specific restriction enzyme A n=1
           Tax=Neisseria subflava NJ9703 RepID=UPI0001A457FB
          Length = 255

 Score =  101 bits (252), Expect = 3e-20,   Method: Composition-based stats.
 Identities = 37/116 (31%), Positives = 54/116 (46%), Gaps = 10/116 (8%)

Query: 166 IKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPY 224
           +       EGS + V V R    Y RDP  +   L++    C  C  N   FY   G  +
Sbjct: 142 VNHQSEYQEGSVQQVMVNR----YERDPKAREACLKKYGYNCSVCNFNFEDFYGEIGKNF 197

Query: 225 LEVHHVIPLSSGGA---DTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277
           + VHH+ P+S+ G    +   +   +CPNCH  LH   N  + IE L + I ++QK
Sbjct: 198 IHVHHLTPVSNNGERYTNPEKDLRPVCPNCHAMLH-KTNRPQRIEDLKLLI-KMQK 251


>UniRef50_Q723Z7 Conserved domain protein n=4 Tax=Listeria monocytogenes
           RepID=Q723Z7_LISMF
          Length = 284

 Score =  101 bits (251), Expect = 3e-20,   Method: Composition-based stats.
 Identities = 39/166 (23%), Positives = 70/166 (42%), Gaps = 22/166 (13%)

Query: 133 SDSFWASIIRGELSELSQPTDDESLLN-----------MRVSKLIKKT----LSQPEGSR 177
           S+ F+++ +   L+ ++    D   +               ++++K+     L +   SR
Sbjct: 99  SNRFYSATLSCYLAYVTFKNSDAEEIMDNQIISTLNNFENPAQVVKENKSTYLVRVPKSR 158

Query: 178 KPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYL-NDGNPYLEVHHVIPLS-- 234
                      Y R+ +      ++   +CE   ++  F    DG PY+E HH+IP++  
Sbjct: 159 ASKRKNNNVYSYPRNYVEAIEARRRCGWVCEFNQEHKTFINIKDGKPYVEGHHLIPMAVQ 218

Query: 235 ---SGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277
                  D  DN + LCP CHR++HY+    E  EML    N  +K
Sbjct: 219 DYYDNTIDFADNIICLCPTCHRKIHYAV-QSEKKEMLIKIFNEREK 263


>UniRef50_B1ZMM6 HNH endonuclease n=1 Tax=Opitutus terrae PB90-1 RepID=B1ZMM6_OPITP
          Length = 279

 Score =  100 bits (250), Expect = 4e-20,   Method: Composition-based stats.
 Identities = 36/136 (26%), Positives = 62/136 (45%), Gaps = 9/136 (6%)

Query: 134 DSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDP 193
           +S W   +      + +              L    +     +++   V  +     R+P
Sbjct: 141 ESVWQEHLNLASKNVGRSVVRALPTEDTFDDLDPSGIGSDGAAKQKHIVSGV----KRNP 196

Query: 194 MVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHR 253
            V+ W+L++S+G+CE  G +          +L+VHH++  + G  D   NCVALCPNCHR
Sbjct: 197 KVRRWVLKRSRGVCERLGCHITRSFA---GFLDVHHILGAAKG--DRVWNCVALCPNCHR 251

Query: 254 ELHYSKNAKELIEMLY 269
           E H + N K++ + L 
Sbjct: 252 ETHCAPNRKKINKELL 267


>UniRef50_Q1L9I8 HNH nuclease n=2 Tax=cellular organisms RepID=Q1L9I8_RALME
          Length = 348

 Score =  100 bits (249), Expect = 5e-20,   Method: Composition-based stats.
 Identities = 44/145 (30%), Positives = 63/145 (43%), Gaps = 12/145 (8%)

Query: 134 DSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPE--GSRKPVEVERLQKVYVR 191
           D  W+     +L  L Q    ES        L       P   GS  P      +    R
Sbjct: 206 DVLWSWPGVSDLCSL-QEVGGESPFGPIDDTLDDLQAPSPAAAGSDSPERRTAERSYVKR 264

Query: 192 DPMVKAWILQQSKGICEN--CGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCP 249
           D  V+  +L ++ G+CEN  C   APF       +L+VHH+  + +  +D   NCVA+CP
Sbjct: 265 DDRVRRQVLDRADGVCENPTCSIRAPF-----PSFLDVHHIFGVET--SDRAWNCVAICP 317

Query: 250 NCHRELHYSKNAKELIEMLYVNINR 274
           NCHR  HY+ +   + E L    +R
Sbjct: 318 NCHRAAHYAPDRSAINEELLRVASR 342


>UniRef50_B1ZSH9 Restriction endonuclease-like protein n=1 Tax=Opitutus terrae
           PB90-1 RepID=B1ZSH9_OPITP
          Length = 261

 Score =  100 bits (248), Expect = 6e-20,   Method: Composition-based stats.
 Identities = 28/123 (22%), Positives = 48/123 (39%), Gaps = 3/123 (2%)

Query: 148 LSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGIC 207
                    +  +    L++    +PEG  +P     +      DP  +   ++    +C
Sbjct: 122 AIHARKAAGVEILPAGDLVRGDFEEPEGFFRPGVATVVIDRLEHDPFARRACIEHYGSVC 181

Query: 208 ENCGKNA-PFYLNDGNPYLEVHHVIPLSS--GGADTTDNCVALCPNCHRELHYSKNAKEL 264
           + CG      Y   G  ++EVH + P+S     AD     + LC NCHR +H    A  +
Sbjct: 182 QACGMRFDKVYGKIGAGFIEVHRLRPVSRPVDSADPVKELIPLCSNCHRMIHRRSPALSV 241

Query: 265 IEM 267
            E+
Sbjct: 242 AEL 244


>UniRef50_Q8TKB6 Hnh endonuclease n=2 Tax=Methanosarcina RepID=Q8TKB6_METAC
          Length = 279

 Score = 99.8 bits (247), Expect = 9e-20,   Method: Composition-based stats.
 Identities = 41/166 (24%), Positives = 72/166 (43%), Gaps = 13/166 (7%)

Query: 118 GNRTKRILINVPGIYSD-SFWASIIRGELSELSQPTDDESLLNMRV--SKLIKKTLSQPE 174
           GN++ R ++   G + D +     +     EL Q  ++   ++ +   S+  + T S  E
Sbjct: 113 GNKS-RFIVPFEGWHEDYNPSKHFVWKLRDELVQALEELGKVDYQTFPSEKDELTSSIVE 171

Query: 175 GSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPL 233
            + +  ++      Y R+   +   +     +C+ CG +    Y   G  Y+EVHHV PL
Sbjct: 172 STPEGKKILCYTTRYERNAQNRRNAIAIHGTVCQGCGFDFEKTYGEIGRDYIEVHHVKPL 231

Query: 234 SSGGADTTDN----CVALCPNCHRELHYSKNA----KELIEMLYVN 271
                    N     + +C NCHR +H  K++    KEL E+L  N
Sbjct: 232 CEEEGSVPINAETDLICVCANCHRMIHRRKDSVLSLKELQELLLAN 277


>UniRef50_Q65MN2 McrA n=2 Tax=Bacillus subtilis group RepID=Q65MN2_BACLD
          Length = 140

 Score = 99.4 bits (246), Expect = 1e-19,   Method: Composition-based stats.
 Identities = 31/117 (26%), Positives = 59/117 (50%), Gaps = 9/117 (7%)

Query: 170 LSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGN-PYLEVH 228
           +SQ     +P+  +  Q+ + R+  + +  +  S   CE    +  F     N PY+E H
Sbjct: 5   VSQKRKRPQPIINQGGQRHWTRNASLASKAMMLSNYTCEIDHTHRTFISKSTNMPYVECH 64

Query: 229 HVIPLSSGG-----ADTTDNCVALCPNCHRELHYSKN--AKELIEMLY-VNINRLQK 277
           H++P++         D   N V+LCP+CHR +HY ++   +++++ LY    + L+K
Sbjct: 65  HLVPIAKQEGFKYDLDQLANLVSLCPHCHRLIHYGQDEEKEKMLKKLYDQRKDHLKK 121


>UniRef50_B0ACA5 Putative uncharacterized protein n=1 Tax=Clostridium bartlettii DSM
           16795 RepID=B0ACA5_9CLOT
          Length = 305

 Score = 99.0 bits (245), Expect = 2e-19,   Method: Composition-based stats.
 Identities = 39/163 (23%), Positives = 70/163 (42%), Gaps = 14/163 (8%)

Query: 129 PGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKK-------TLSQPEGSRKPVE 181
           P   S+     I   E+  + +   +E+ +   +   I K       T    +  ++   
Sbjct: 128 PSKVSEELANYIKSNEIDMIKETLQEENNIEYDLKNYIDKINVDENFTYKYDKKKKQKYT 187

Query: 182 VERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGN-PYLEVHHVIPLS-----S 235
           ++   K Y+RD  V    L+++   CE   ++  F   +    Y E HH++P++      
Sbjct: 188 IQNGIKTYIRDRKVAMNALKKANHKCEVDSEHEVFLRRNVEVGYTESHHLVPMAYSDIFD 247

Query: 236 GGADTTDNCVALCPNCHRELHYSKNAKELIEMLYV-NINRLQK 277
              D  +N V+LC +CH  LHY K  + ++E LY   +N L K
Sbjct: 248 VSLDVEENIVSLCSHCHNLLHYGKEFERVLEQLYYERVNHLNK 290


>UniRef50_A0L1U4 HNH endonuclease n=1 Tax=Shewanella sp. ANA-3 RepID=A0L1U4_SHESA
          Length = 224

 Score = 98.6 bits (244), Expect = 2e-19,   Method: Composition-based stats.
 Identities = 31/99 (31%), Positives = 46/99 (46%), Gaps = 9/99 (9%)

Query: 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIP 232
           EGS K V V +    Y RD   +   +      C+ CG N +  Y   G  ++EVHH+ P
Sbjct: 123 EGSVKRVLVNK----YERDAKARKACIAHHGCQCKVCGFNFSETYGLHGEGFIEVHHITP 178

Query: 233 LSSGGA----DTTDNCVALCPNCHRELHYSKNAKELIEM 267
           LS+       D  ++ + +C NCH  LH  K    + E+
Sbjct: 179 LSTISKSYQVDPINDLIPVCSNCHSMLHRGKEPLSIDEL 217


>UniRef50_C3RB64 Predicted protein n=1 Tax=Bacteroides dorei 5_1_36/D4
           RepID=C3RB64_9BACE
          Length = 274

 Score = 97.9 bits (242), Expect = 3e-19,   Method: Composition-based stats.
 Identities = 33/120 (27%), Positives = 50/120 (41%), Gaps = 10/120 (8%)

Query: 158 LNMRVSKLIKKTLSQPEGSRKPVEVERLQK-----VYVRDPMVKAWILQQSKGICENCGK 212
             +  S L    +S+ E  +K V+ E   +      Y R+P+ +   L +    C  CG 
Sbjct: 148 FELIFSLLTITDISEEEFLQKAVQTEGTIQEIKSIRYERNPINRKLCLYKKGYTCAVCGM 207

Query: 213 N-APFYLNDGNPYLEVHHVIPLSSGGA----DTTDNCVALCPNCHRELHYSKNAKELIEM 267
           N    Y + G  ++EVHH  P+S  G     D   + V LC NCH   H       + E+
Sbjct: 208 NFQDVYGDIGKGFIEVHHTTPVSKMGEGYNLDIERDLVPLCSNCHSMTHRRNPPYSVEEL 267


>UniRef50_A3U4A6 E14 prophage-like protein n=1 Tax=Oceanicola batsensis HTCC2597
           RepID=A3U4A6_9RHOB
          Length = 201

 Score = 97.5 bits (241), Expect = 4e-19,   Method: Composition-based stats.
 Identities = 33/126 (26%), Positives = 60/126 (47%), Gaps = 5/126 (3%)

Query: 137 WASIIRGELSELSQPTDDESLLNM---RVSKLIKKTLSQPEGSRKPVE-VERLQKVYVRD 192
           +A+       +  +    ++  N    R  + I   L Q + S + V+  +++ + + R+
Sbjct: 31  YAATEAEAGVDAEEKPPKKAPYNAKAGRTEEAIAADLFQDDSSSEEVKKTQKVIETFERN 90

Query: 193 PMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252
                  L++    C+  G +  F   +G PYLEVHH++PL  GG+D   N V +  + H
Sbjct: 91  RKAVRD-LKRLYKTCQVTGDDFVFSKVNGEPYLEVHHLVPLGEGGSDDPANLVVISAHIH 149

Query: 253 RELHYS 258
           R LHY+
Sbjct: 150 RMLHYA 155


>UniRef50_C6MKA5 HNH endonuclease n=1 Tax=Geobacter sp. M18 RepID=C6MKA5_9DELT
          Length = 254

 Score = 97.1 bits (240), Expect = 6e-19,   Method: Composition-based stats.
 Identities = 34/130 (26%), Positives = 57/130 (43%), Gaps = 6/130 (4%)

Query: 150 QPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERL-QKVYVRDPMVKAWILQQSKGICE 208
           Q +    +    + K I+    + +G R    V++   K Y R+P+ +   ++    +C 
Sbjct: 122 QVSFASEVTEAVLVKAIEAEEIEDKGPRFEGGVQQYFGKRYERNPVNRLEAIRYHGLVCN 181

Query: 209 NCGKN-APFYLNDGNPYLEVHHVIPLS----SGGADTTDNCVALCPNCHRELHYSKNAKE 263
            CG N    Y   G+ Y+EVHHV P+S        D   + + +C NCHR +H + N   
Sbjct: 182 VCGFNFEEVYGERGSGYIEVHHVEPISTYDGEQPVDPKTDLITVCSNCHRMIHRNPNDVL 241

Query: 264 LIEMLYVNIN 273
            I+     I 
Sbjct: 242 TIQQAQAIIR 251


>UniRef50_B3EB35 HNH endonuclease n=1 Tax=Geobacter lovleyi SZ RepID=B3EB35_GEOLS
          Length = 281

 Score = 97.1 bits (240), Expect = 6e-19,   Method: Composition-based stats.
 Identities = 34/106 (32%), Positives = 49/106 (46%), Gaps = 9/106 (8%)

Query: 173 PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVI 231
           PEG+   V V +    Y R P+ +A  +     +C  CG +    Y   G  Y+EVHH I
Sbjct: 177 PEGACIKVIVNK----YERSPVNRAVCIAVYGTVCHVCGFDFGKVYGQIGKGYIEVHHRI 232

Query: 232 PLSSGGA----DTTDNCVALCPNCHRELHYSKNAKELIEMLYVNIN 273
           P+S  GA    D   + V LC NCH  +H +    EL  +  + + 
Sbjct: 233 PVSKMGASYVIDPIRDLVPLCSNCHSAVHRTDPPVELEALRSIVVT 278


>UniRef50_B8KVR3 HNH endonuclease domain protein n=1 Tax=gamma proteobacterium
           NOR51-B RepID=B8KVR3_9GAMM
          Length = 289

 Score = 97.1 bits (240), Expect = 6e-19,   Method: Composition-based stats.
 Identities = 37/155 (23%), Positives = 65/155 (41%), Gaps = 9/155 (5%)

Query: 127 NVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSK-LIKKTLSQPEGSRKPVEVERL 185
           N P  +  S  +++     S+       +    + V   + +K ++ PE +  P E   +
Sbjct: 117 NEPLPFIGSCSSALFDSITSDDDVVKAVQRDFALDVDDDVYQKLVAAPEDAVVPKEYRAM 176

Query: 186 QKVYVRDPMVKAWILQQSKGICENCGKNA-PFYLNDGNPYLEVHHVIPLSSGGA-----D 239
           +  Y R   V    L+ +   CE    +  P     G P +EVHH++P+S         D
Sbjct: 177 R--YERSAAVGREALESAGYACEFDNTHETPLSAVTGQPIMEVHHLVPISKSAEFRCSLD 234

Query: 240 TTDNCVALCPNCHRELHYSKNAKELIEMLYVNINR 274
              N V+LCPNCH  +H S    ++  +  +  +R
Sbjct: 235 VLANVVSLCPNCHSAIHRSTKTVQVAMLQKLFGDR 269


>UniRef50_C8U495 Endonuclease-like protein n=2 Tax=Escherichia coli
           RepID=C8U495_ECO10
          Length = 246

 Score = 96.7 bits (239), Expect = 7e-19,   Method: Composition-based stats.
 Identities = 43/178 (24%), Positives = 68/178 (38%), Gaps = 21/178 (11%)

Query: 102 GYQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMR 161
           GY  Y     R+E  + +   +I           F  +I+R  L++++         +  
Sbjct: 80  GYSLYIFYQIRQEKTTASGAAKI---------KDFEKNIVRKYLTKINSNWYATDEEHYS 130

Query: 162 VSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLND 220
            +  I       EG     ++ERL   Y RDP  +   +      C  CG N    Y + 
Sbjct: 131 YTPEIDNDY--YEGR----QLERLATYYERDPKARQACIDAHGYTCHICGFNFEKVYGSI 184

Query: 221 GNPYLEVHHVIPLSSGGA----DTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINR 274
           G  Y++VHH+ PL         D  ++ + LC NCH  +H        IE L   + R
Sbjct: 185 GKNYIQVHHIKPLHHIAKYHKVDPVNDLIPLCANCHVMIHNGM-EVRTIEQLREILER 241


>UniRef50_Q3K789 Putative HNH endonuclease n=1 Tax=Pseudomonas fluorescens Pf0-1
           RepID=Q3K789_PSEPF
          Length = 323

 Score = 96.7 bits (239), Expect = 9e-19,   Method: Composition-based stats.
 Identities = 38/114 (33%), Positives = 58/114 (50%), Gaps = 13/114 (11%)

Query: 162 VSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICE--NCGKNAPFYLN 219
           V+ L    L + E SR    V R+     RDP V+  ++ +  G CE   CG +  +   
Sbjct: 212 VAGLDLSLLGRDEASRYQATVSRV----ARDPSVRKAVIDRCNGRCERPGCGASRSYSG- 266

Query: 220 DGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNIN 273
               +L+VHH+  L    +D   NCVALCPNCHR+ H+S + ++L + L +   
Sbjct: 267 ----FLDVHHI--LGVEISDRVANCVALCPNCHRDAHFSADRQKLNDSLLIVAQ 314


>UniRef50_B0N4T9 Putative uncharacterized protein n=1 Tax=Clostridium ramosum DSM
           1402 RepID=B0N4T9_9FIRM
          Length = 329

 Score = 96.3 bits (238), Expect = 9e-19,   Method: Composition-based stats.
 Identities = 42/109 (38%), Positives = 55/109 (50%), Gaps = 7/109 (6%)

Query: 176 SRKPVEVE-RLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLN-DGNPYLEVHHVIPL 233
             KP  VE +  KVY R+  V    L  +   CE   K+  F    DG PY E HH+IP+
Sbjct: 204 KPKPKLVENKFNKVYKRNKAVAINALGIANFSCEIDKKHKTFKRKKDGVPYTEPHHLIPM 263

Query: 234 S-----SGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277
           +         D  +N V+LC NCH E+HY +NA+ELI  LY     L +
Sbjct: 264 AFQDEFDFSIDIEENIVSLCSNCHNEIHYGENARELITKLYYERKSLLE 312


>UniRef50_Q60BH4 Putative uncharacterized protein n=1 Tax=Methylococcus capsulatus
           RepID=Q60BH4_METCA
          Length = 311

 Score = 95.9 bits (237), Expect = 1e-18,   Method: Composition-based stats.
 Identities = 33/138 (23%), Positives = 54/138 (39%), Gaps = 18/138 (13%)

Query: 135 SFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPM 194
           +F A I+       ++      LL  ++ +         EG+ K + V      Y R+P 
Sbjct: 179 NFRAEILDRV---YTESKPGLGLLPEQIDE----PQEFYEGASKSITVN----AYERNPQ 227

Query: 195 VKAWILQQSKGICENCGK--NAPFYLNDGNPYLEVHHVIPL----SSGGADTTDNCVALC 248
            +   ++     C  CG   +   Y   G  ++ VHH+ PL    +    D  ++   +C
Sbjct: 228 ARNACIEHYGAKCIICGFVFHEK-YGEIGKGFIHVHHIKPLGEICAEYQVDPINDLCPVC 286

Query: 249 PNCHRELHYSKNAKELIE 266
           PNCH  LH  K    L E
Sbjct: 287 PNCHAMLHMRKPPYSLNE 304


>UniRef50_Q81E47 5-methylcytosine-specific restriction enzyme A n=15 Tax=Bacillus
           cereus group RepID=Q81E47_BACCR
          Length = 97

 Score = 95.5 bits (236), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 31/96 (32%), Positives = 51/96 (53%), Gaps = 8/96 (8%)

Query: 182 VERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDG-NPYLEVHHVIPLS-----S 235
           +E  ++V+ RDP      ++Q++  CE    +  F        Y+E HH+IPL       
Sbjct: 1   MESGREVWPRDPKKAKQAIKQAEFKCEIDDTHETFVSEASRKNYMEAHHLIPLRMQHDFE 60

Query: 236 GGADTTDNCVALCPNCHRELHYS--KNAKELIEMLY 269
              D   N V++CPNCHR +HY   K+ K+++E+L+
Sbjct: 61  NSLDVVGNIVSICPNCHRLIHYGRDKDKKKVLELLF 96


>UniRef50_C6LDW0 Product McrA n=1 Tax=Bryantella formatexigens DSM 14469
           RepID=C6LDW0_9FIRM
          Length = 380

 Score = 94.4 bits (233), Expect = 4e-18,   Method: Composition-based stats.
 Identities = 51/206 (24%), Positives = 83/206 (40%), Gaps = 35/206 (16%)

Query: 97  RLKMCGYQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDES 156
           RL   G  A F + G  E+P     K +    PG       +  ++  L E+S   D   
Sbjct: 170 RLFAVGIPAEFYQ-GNYELPQEGLLKHL--ESPG-------SVTVKSALKEVSDSVDAGV 219

Query: 157 LL---NMRVSKLIKKTLSQPEGSRKPVEV---ERLQKVYVR---------DPMVKAWILQ 201
           ++         + ++ +++ +G   P E    + +     R         +P +    ++
Sbjct: 220 MITGAEAISDSIYQQLVNEADGDISPAEYAAEKYIPPAAERSVSSDRPATNPRLGKAAIK 279

Query: 202 QSKGICENCGK---NAPFYLNDGNPYLEVHHVIPLSSGGA-----DTTDNCVALCPNCHR 253
           +S   C        +  F   DG PYLEVHH+IPL    A     DT  N + LCP CHR
Sbjct: 280 RSGYKCIFSTDAEPHKTFLKPDGTPYLEVHHLIPLKQQPAFEYKLDTMANLIPLCPLCHR 339

Query: 254 ELHYS--KNAKELIEMLYVNINRLQK 277
            LH+    +  E++  LY   + + K
Sbjct: 340 RLHHGCRADVDEMLTQLYEERHEILK 365


>UniRef50_B3CDE4 Putative uncharacterized protein n=1 Tax=Bacteroides intestinalis
           DSM 17393 RepID=B3CDE4_9BACE
          Length = 261

 Score = 94.4 bits (233), Expect = 4e-18,   Method: Composition-based stats.
 Identities = 31/107 (28%), Positives = 53/107 (49%), Gaps = 10/107 (9%)

Query: 169 TLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEV 227
           T    EGS +   V R    Y R+P+ +   +++   IC+ CG + +  Y   GN ++ V
Sbjct: 157 TEEYYEGSLQQALVNR----YERNPIARKKCIEKHGCICQVCGMDFSKVYGELGNGFIHV 212

Query: 228 HHVIPLS-----SGGADTTDNCVALCPNCHRELHYSKNAKELIEMLY 269
           HH++P+S     +   +  +  V +CPNCH  LH  K + E +  + 
Sbjct: 213 HHIVPISALKGEAHKIEPENGLVPVCPNCHAMLHKGKLSIEELRKIL 259


>UniRef50_D1BJK4 HNH endonuclease n=1 Tax=Sanguibacter keddieii DSM 10542
           RepID=D1BJK4_SANKS
          Length = 395

 Score = 94.4 bits (233), Expect = 4e-18,   Method: Composition-based stats.
 Identities = 39/113 (34%), Positives = 54/113 (47%), Gaps = 8/113 (7%)

Query: 168 KTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICEN--CGKNAPFYLNDGNPYL 225
           + L+  E + +P  V R+   Y R    +  +L +S G CE+  C          G P L
Sbjct: 274 RRLADLERTTEPQTVSRI--AYQRQYAARRAVLIRSAGQCESERCTGMPAELNRKGMPIL 331

Query: 226 EVHHVIPLSSGGADTTDNCVALCPNCH----RELHYSKNAKELIEMLYVNINR 274
           +V H++ LS GGAD   N VALCPNCH    R  H  +  KEL  +     +R
Sbjct: 332 DVDHIVELSQGGADHPLNMVALCPNCHAAKTRGQHAKRWEKELRRIAQAAHDR 384


>UniRef50_C0ZFI2 Putative uncharacterized protein n=1 Tax=Brevibacillus brevis NBRC
           100599 RepID=C0ZFI2_BREBN
          Length = 360

 Score = 93.6 bits (231), Expect = 7e-18,   Method: Composition-based stats.
 Identities = 55/221 (24%), Positives = 85/221 (38%), Gaps = 22/221 (9%)

Query: 73  HSLD-ERKIHPGEYFTL---IGNSPRDIRLKMCGYQAYFSRTGRKEIPSGNRTKRILINV 128
            SLD +R I P E   L     N+       +CG   Y+       +P   + K  L N+
Sbjct: 128 QSLDIDRTIFPNESIDLKASTTNAKNYTAAHICG--KYYDALA---LPDDEQLKVDLKNL 182

Query: 129 PGIYSD---SFWASIIRGELSELSQPTD-DESLLNMRVSKLIKKTLSQPEGSRKPVEVER 184
             IY               L    Q  + +++     V                P     
Sbjct: 183 LKIYEQLKIQMAGRGTEEMLDYYLQKEEIEDTQFQSDVQVAEPSNTPLVPQPVPPQVESN 242

Query: 185 LQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLN-DGNPYLEVHHVIPLS-----SGGA 238
            ++ + R+  +    L+    +CE    +  F        ++E HH+IP+      S   
Sbjct: 243 GKQQWKRNASIAKEALRNEDYLCEVNNGHLSFTSAITNKNFVEAHHLIPMKLQALFSWSL 302

Query: 239 DTTDNCVALCPNCHRELHYSKN--AKELIEMLYV-NINRLQ 276
           D   N V+LCPNCHR++H++     KELIE+LY   INRL+
Sbjct: 303 DVPGNIVSLCPNCHRKIHHASKSERKELIEVLYSKKINRLK 343


>UniRef50_UPI0001BC7B91 HNH endonuclease n=1 Tax=Bacteroides sp. D2 RepID=UPI0001BC7B91
          Length = 235

 Score = 93.2 bits (230), Expect = 9e-18,   Method: Composition-based stats.
 Identities = 27/107 (25%), Positives = 44/107 (41%), Gaps = 6/107 (5%)

Query: 172 QPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHV 230
           +     +    +     + R+  ++   L+     C+ CG N    Y   G  Y+EVHH+
Sbjct: 126 EEAALTEGKLHQVSLTKHERNQALRQLCLKHYGYTCQVCGMNFEAVYGKLGKNYIEVHHI 185

Query: 231 IPLSS-GGA---DTTDNCVALCPNCHRELHYSKNAKELI-EMLYVNI 272
            P++   G    D     + LC NCH  +H  KN + L  E L   +
Sbjct: 186 NPIAETDGEHVLDPKTGLIPLCSNCHSMIHRGKNGRVLTPEELKAIL 232


>UniRef50_B9DID5 Putative uncharacterized protein n=1 Tax=Staphylococcus carnosus
           subsp. carnosus TM300 RepID=B9DID5_STACT
          Length = 242

 Score = 93.2 bits (230), Expect = 9e-18,   Method: Composition-based stats.
 Identities = 33/119 (27%), Positives = 50/119 (42%), Gaps = 9/119 (7%)

Query: 145 LSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSK 204
           LSE  +    ES ++  +   I K     EG +K V V +    Y R+P  +   +    
Sbjct: 123 LSEKLKSYLLESEIHYVLYPEIIKDEELYEGIKKQVIVNK----YERNPKARQICVNYYG 178

Query: 205 GICENCGKN-APFYLNDGNPYLEVHHVIPLSS----GGADTTDNCVALCPNCHRELHYS 258
             C+ C  N    Y   G  ++ VHH++PLS        D   +   +CPNCH  +H  
Sbjct: 179 YNCKVCDLNFEKEYGEIGKNFIHVHHIVPLSKIDEQYKIDPIKDLRPVCPNCHAMIHRG 237


>UniRef50_Q0AUW7 Hnh endonuclease n=1 Tax=Syntrophomonas wolfei subsp. wolfei str.
           Goettingen RepID=Q0AUW7_SYNWW
          Length = 274

 Score = 92.8 bits (229), Expect = 1e-17,   Method: Composition-based stats.
 Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 5/106 (4%)

Query: 158 LNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APF 216
           L+  V    +    Q E   +  +++ +   Y R+   +   + +    C  C  +   F
Sbjct: 154 LHGEVQLAQEVDEEQTEKLYEGAKIQIVVNAYERNIKARQICIDKYGYKCSICDFDFEEF 213

Query: 217 YLNDGNPYLEVHHVIPLSS----GGADTTDNCVALCPNCHRELHYS 258
           Y   G+ Y+EVHH+IPL         D  ++   +CPNCH  LH +
Sbjct: 214 YGMLGSDYIEVHHLIPLHEINKEYRVDPINDLRPVCPNCHAMLHRA 259


>UniRef50_C3G8U4 HNH endonuclease n=1 Tax=Bacillus thuringiensis serovar
           andalousiensis BGSC 4AW1 RepID=C3G8U4_BACTU
          Length = 258

 Score = 92.1 bits (227), Expect = 2e-17,   Method: Composition-based stats.
 Identities = 35/138 (25%), Positives = 58/138 (42%), Gaps = 11/138 (7%)

Query: 144 ELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQS 203
           +L    +   +  +        + + LS  EG+RK V V +    Y R  + +   ++  
Sbjct: 125 DLLTYIERCFNNDISKSVYPDEVPEQLSIMEGNRKTVVVNQ----YERSAVARRKCIEHH 180

Query: 204 KGICENCGKNAPF-YLNDGNPYLEVHHVIPLSSGG----ADTTDNCVALCPNCHRELHYS 258
              C  C  +    Y + G  ++ VHH IPLS  G     D  ++ + +CPNCH  LH  
Sbjct: 181 GCYCHVCHLDFKKQYGSLGKGFIHVHHKIPLSEIGDEYEVDYVNDLIPVCPNCHAMLHRK 240

Query: 259 KNAKELI--EMLYVNINR 274
                 +  E L V +N+
Sbjct: 241 SMNGSFLTIEELKVLMNK 258


>UniRef50_B5G9G0 HNH endonuclease n=1 Tax=Streptomyces sp. SPB74 RepID=B5G9G0_9ACTO
          Length = 272

 Score = 91.7 bits (226), Expect = 3e-17,   Method: Composition-based stats.
 Identities = 34/127 (26%), Positives = 55/127 (43%), Gaps = 12/127 (9%)

Query: 156 SLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVK----AWILQQSKGI-CENC 210
               +   +     +  PEG      + R  +   R+  ++    A +L+Q   + CE C
Sbjct: 130 QPAPLNEDEDQDDDVGAPEGRV----LYRRHRTRERNKGLRKKKIASVLKQGGALSCEAC 185

Query: 211 GKN-APFYLNDGNPYLEVHHVIPLSSGGADT--TDNCVALCPNCHRELHYSKNAKELIEM 267
           G +   FY   G+ Y+E HHV+PL   G  T    +   +C NCHR +H S       E+
Sbjct: 186 GFDFGKFYGERGDGYIECHHVVPLHEAGEGTTRLADLALICSNCHRMIHRSAPWPTPAEL 245

Query: 268 LYVNINR 274
             V ++R
Sbjct: 246 RLVVLDR 252


>UniRef50_A0YCZ6 Putative uncharacterized protein n=1 Tax=marine gamma
           proteobacterium HTCC2143 RepID=A0YCZ6_9GAMM
          Length = 267

 Score = 91.3 bits (225), Expect = 3e-17,   Method: Composition-based stats.
 Identities = 32/129 (24%), Positives = 56/129 (43%), Gaps = 9/129 (6%)

Query: 154 DESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN 213
               + +  +  + K  S  EG+ K + V      Y R+P  +   +++    C  C  +
Sbjct: 143 RTGAVEISYADEVPKDNSLKEGAAKKIWVN----AYERNPDARERCIRKWGLNCVVCNFH 198

Query: 214 -APFYLNDGNPYLEVHHVIPLSS----GGADTTDNCVALCPNCHRELHYSKNAKELIEML 268
               Y + G  Y+ VHH+ PL+        +  ++   +CPNCH  LH +KN+   IE L
Sbjct: 199 FEQCYGHLGKRYIHVHHLKPLAEIQKEYEVNPEEDLRPVCPNCHSMLHRNKNSVLSIEEL 258

Query: 269 YVNINRLQK 277
              +N   +
Sbjct: 259 QTLVNMYSR 267


>UniRef50_D1P9G2 5-methylcytosine-specific restriction enzyme A n=1 Tax=Prevotella
           copri DSM 18205 RepID=D1P9G2_9BACT
          Length = 251

 Score = 91.3 bits (225), Expect = 4e-17,   Method: Composition-based stats.
 Identities = 28/145 (19%), Positives = 58/145 (40%), Gaps = 17/145 (11%)

Query: 150 QPTDDESLLNMRVSKLIKKTLSQPEGSRKP----------VEVERLQKVYVRDPMVKAWI 199
           +     +L   +++     + ++P     P            + +   V  R+P ++   
Sbjct: 99  ESKAFRNLFKTKIAIEDLSSDAEPSAPSTPSFREETEGERKHILKETDVIRRNPQLRQMC 158

Query: 200 LQQSKGICENCG--KNAPFYLNDGNPYLEVHHVIPLSSGGAD-----TTDNCVALCPNCH 252
           L +    C+ CG      +    G  ++EVHH+  +S+   D       +N V LC NCH
Sbjct: 159 LDKYGYQCQCCGMDFEETYGKELGVNFMEVHHIRMISTYETDGVPENFLENLVPLCSNCH 218

Query: 253 RELHYSKNAKELIEMLYVNINRLQK 277
             +H+ K+++  +  L      ++K
Sbjct: 219 SMIHHIKDSEHPLRDLREAYRGIKK 243


>UniRef50_C4UQ38 Putative uncharacterized protein n=1 Tax=Yersinia rohdei ATCC 43380
           RepID=C4UQ38_YERRO
          Length = 206

 Score = 90.9 bits (224), Expect = 4e-17,   Method: Composition-based stats.
 Identities = 44/171 (25%), Positives = 71/171 (41%), Gaps = 15/171 (8%)

Query: 112 RKEIPSGNRTKRILINVPG-IYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTL 170
           R  I S     R++  + G  Y+DSF ++        LS    + S  +    +++  + 
Sbjct: 42  RTTISSNEEITRLISKMSGGYYADSFVSNCSTAMRRYLSFVNSELSYFH-YPDEILNHS- 99

Query: 171 SQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHH 229
              EG++K + V      Y RD   +   ++     C  C  N    Y   G  ++ VHH
Sbjct: 100 EYIEGAKKQIIVN----SYERDRDARNKAIEIHGLNCSVCDMNFEDVYGEIGVGFIHVHH 155

Query: 230 VIPLSSGGA----DTTDNCVALCPNCHRELHYSKNA---KELIEMLYVNIN 273
           + PL         D  D+ + +CPNCH  LH  KN    KEL +++   I 
Sbjct: 156 LKPLHEINKEYHVDPEDDLITVCPNCHAMLHRLKNRPSKKELKDLIKKKIT 206


>UniRef50_C5RG47 HNH endonuclease n=1 Tax=Clostridium cellulovorans 743B
           RepID=C5RG47_CLOCL
          Length = 396

 Score = 90.5 bits (223), Expect = 5e-17,   Method: Composition-based stats.
 Identities = 29/130 (22%), Positives = 50/130 (38%), Gaps = 6/130 (4%)

Query: 144 ELSELSQPTDDESLLNMRVS-KLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQ 202
           EL EL      ++   +R    L+ + +  PE   +    +     Y R+   +   ++ 
Sbjct: 260 ELEELWSSFSGKTTEIIRTKVDLLAEEVINPERYIEGSTRQIYVNAYERNKKARNKCIEI 319

Query: 203 SKGICENCGKN-APFYLNDGNPYLEVHHVIPLS----SGGADTTDNCVALCPNCHRELHY 257
               C  CG N    Y      ++ VHH+ P+S        D   + V +CPNCH  +H 
Sbjct: 320 YGYNCSVCGVNLEEIYGEIAKEFIHVHHIKPISSINQEYEIDPETDLVPICPNCHAVIHR 379

Query: 258 SKNAKELIEM 267
                 + E+
Sbjct: 380 RNQDISISEL 389


>UniRef50_A9AZQ2 HNH endonuclease n=1 Tax=Herpetosiphon aurantiacus ATCC 23779
           RepID=A9AZQ2_HERA2
          Length = 271

 Score = 90.5 bits (223), Expect = 5e-17,   Method: Composition-based stats.
 Identities = 34/150 (22%), Positives = 61/150 (40%), Gaps = 20/150 (13%)

Query: 122 KRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVE 181
           K+ + NV  +  D  W++ I+  L +L                   + ++ PE   +  E
Sbjct: 130 KQSIQNVSTVEED--WSAAIQANLFDLPSTQP-------------HQPIASPEIFIEGAE 174

Query: 182 VERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSSGGA-- 238
            + L   Y R+P  +   ++     C  C  + A  Y      ++ VHH+ PL++ G   
Sbjct: 175 YQSLVTRYERNPEARQRCIEHYGSTCVICHFDFAKVYGELAKGFIHVHHLKPLATIGENY 234

Query: 239 --DTTDNCVALCPNCHRELHYSKNAKELIE 266
             +  D+   +CPNCH  +H  K    + E
Sbjct: 235 EVNPIDDLRPVCPNCHAVIHMRKEPYTIDE 264


>UniRef50_UPI0001BC350E HNH endonuclease n=1 Tax=Butyrivibrio crossotus DSM 2876
           RepID=UPI0001BC350E
          Length = 263

 Score = 89.8 bits (221), Expect = 8e-17,   Method: Composition-based stats.
 Identities = 35/164 (21%), Positives = 55/164 (33%), Gaps = 20/164 (12%)

Query: 131 IYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPV---------- 180
           ++ DS   S I     +  +       +  +    I K   + + S  PV          
Sbjct: 91  VFEDSITKSDILKIWKDFKKFNSVAQNVPEKYMDAINKLCEEKKKSHIPVLESNESFVIN 150

Query: 181 -----EVERLQKVYVRDPMVKAWILQQSKGICENCGKNA-PFYLNDGNPYLEVHHVIPL- 233
                 +E     Y R    +   ++     C+ CG +    Y   G  Y+EVHH  PL 
Sbjct: 151 KAEGNRIEFYTTRYERVAKYREAAIKIHGTKCQICGFDFNKKYGYIGENYIEVHHKKPLF 210

Query: 234 ---SSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINR 274
                   +   + + +C NCHR +H  KN     E L   I  
Sbjct: 211 SLDEELIPNPETDMITICSNCHRMIHRKKNDIITPEKLKDAIRE 254


>UniRef50_C9ADX3 5-methylcytosine-specific restriction enzyme A n=2 Tax=Enterococcus
           faecium RepID=C9ADX3_ENTFC
          Length = 253

 Score = 89.8 bits (221), Expect = 9e-17,   Method: Composition-based stats.
 Identities = 32/131 (24%), Positives = 51/131 (38%), Gaps = 13/131 (9%)

Query: 141 IRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWIL 200
              E++    P+ D++ +  +  K  K      EG +    + R   +Y RDP  +   L
Sbjct: 120 ETTEITWKMIPSMDQATVKEQTLKRKKFL----EGRK----INRYVNIYERDPRARKACL 171

Query: 201 QQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSS----GGADTTDNCVALCPNCHREL 255
                 C  C  N    Y   G  ++ VHH   LS        D  ++   +CPNCH  +
Sbjct: 172 GHYGYRCVVCKFNFEETYGEIGKEFIHVHHEKELSMLDEFYEIDPIEDMKPVCPNCHAMI 231

Query: 256 HYSKNAKELIE 266
           H  + A  + E
Sbjct: 232 HRKRPAYTIEE 242


>UniRef50_A9GYN9 Putative uncharacterized protein n=1 Tax=Roseobacter litoralis Och
           149 RepID=A9GYN9_9RHOB
          Length = 311

 Score = 89.8 bits (221), Expect = 1e-16,   Method: Composition-based stats.
 Identities = 34/142 (23%), Positives = 54/142 (38%), Gaps = 11/142 (7%)

Query: 137 WASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVK 196
           W      + SE       + L            L +PE  R+    E       R+P+ +
Sbjct: 165 WGLATNKKGSEFISHRARDGLRKAGFECADLGNLVEPELLREGSIRETTNVRRERNPVAR 224

Query: 197 AWILQQSKG------ICENCGKN-APFYLNDGNPYLEVHHVIPLSSGGAD----TTDNCV 245
              ++  +       IC  CG + A FY   G  ++ VHH+ P+S   A        + V
Sbjct: 225 VLCIEHYRKKNDGRLICIVCGFDFAAFYGTLGEGFIHVHHLNPISEAEASRIVSPEIDLV 284

Query: 246 ALCPNCHRELHYSKNAKELIEM 267
            +CPNCH  +H     + + EM
Sbjct: 285 PVCPNCHSMIHRGGQTRSIAEM 306


>UniRef50_A7I926 HNH endonuclease n=1 Tax=Candidatus Methanoregula boonei 6A8
           RepID=A7I926_METB6
          Length = 266

 Score = 89.4 bits (220), Expect = 1e-16,   Method: Composition-based stats.
 Identities = 32/127 (25%), Positives = 58/127 (45%), Gaps = 14/127 (11%)

Query: 155 ESLLNMRVSKLIKKTLSQ-------PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGIC 207
           ES  ++   ++ K+TL++       PE   +  E E +Q +Y R+  ++   ++     C
Sbjct: 134 ESEWDILSKEIEKRTLTKYEEIFTCPEYFTEGKEREIIQTIYERNSKLREMAIKMHGTTC 193

Query: 208 ENCGKN-APFYLNDGNPYLEVHHVIPLS------SGGADTTDNCVALCPNCHRELHYSKN 260
             CG N A  Y      Y+E+HH++P S          +   + + LC NCHR +H  + 
Sbjct: 194 SVCGFNFAKKYGILSEGYIEIHHLVPHSEHKIKGESEINPETDLIPLCSNCHRIIHKPEK 253

Query: 261 AKELIEM 267
              + E+
Sbjct: 254 MLSIEEL 260


>UniRef50_Q8VUW2 Putative uncharacterized protein 5'-methylcytosine-specific
           restiction enxyme A of Methanosarcima mazei n=1
           Tax=Staphylococcus hominis RepID=Q8VUW2_STAHO
          Length = 211

 Score = 89.0 bits (219), Expect = 2e-16,   Method: Composition-based stats.
 Identities = 25/102 (24%), Positives = 46/102 (45%), Gaps = 5/102 (4%)

Query: 177 RKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSS 235
           ++   +++    + R+  ++   ++     C+ CG N    Y N G  ++E+HH+ P+  
Sbjct: 108 KEGKILKKYGSKFERNSKLREKAIEIHGVTCKVCGFNFEKKYGNIGKNFIEIHHIKPMYD 167

Query: 236 GGADTTDN----CVALCPNCHRELHYSKNAKELIEMLYVNIN 273
              +   N     + LC NCH+ +H SK     IE L   I 
Sbjct: 168 IRKEILVNPQTDLIPLCSNCHKMIHRSKRKPYTIEQLKSMIK 209


>UniRef50_Q64YP3 Putative uncharacterized protein n=1 Tax=Bacteroides fragilis
           RepID=Q64YP3_BACFR
          Length = 216

 Score = 89.0 bits (219), Expect = 2e-16,   Method: Composition-based stats.
 Identities = 35/132 (26%), Positives = 59/132 (44%), Gaps = 10/132 (7%)

Query: 145 LSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSK 204
           LS L +     +L  + + +++       E      ++ R  +  +R+  +   +  +  
Sbjct: 69  LSSLVEYIHFNNLDRLYIEEIVSLKKIPEEAR----QIRREIEAILRNQKLVDELKIRYN 124

Query: 205 GICENCGKNAPFYLNDGNPYLEVHHVIPLSS--GGADTTDNCVALCPNCHRELHYSKNA- 261
            +C+ CG        +   Y EVHH+ PL     G+DT DN V +CPNCH  L Y     
Sbjct: 125 NVCQICGTQIKI--GENKYYSEVHHIWPLGKPHNGSDTLDNMVCVCPNCHTLLDYKAIHL 182

Query: 262 -KELIEMLYVNI 272
            KE+ ++L  NI
Sbjct: 183 NKEIFKVLKHNI 194


>UniRef50_D2QLF4 HNH endonuclease n=1 Tax=Spirosoma linguale DSM 74
           RepID=D2QLF4_9SPHI
          Length = 367

 Score = 88.6 bits (218), Expect = 2e-16,   Method: Composition-based stats.
 Identities = 29/119 (24%), Positives = 49/119 (41%), Gaps = 9/119 (7%)

Query: 154 DESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN 213
           D   +     + +  T +  EG+ K + V R    Y RD   +   +      C+ C  +
Sbjct: 226 DPEKVPFHYPEEVPSTKTYVEGAVKQITVNR----YERDQDARTDCINHYGAKCQACEFD 281

Query: 214 -APFYLNDGNPYLEVHHVIPLSSGGA----DTTDNCVALCPNCHRELHYSKNAKELIEM 267
               Y N G  Y+ VHH+ P +        D   + + +CPNCH  LH  K   ++ ++
Sbjct: 282 FEEIYGNIGKGYIHVHHIKPFNEIKTSYRVDPIKDLIPVCPNCHAMLHTGKEVMDIADL 340


>UniRef50_Q0HF94 Putative uncharacterized protein n=1 Tax=Shewanella sp. MR-4
           RepID=Q0HF94_SHESM
          Length = 295

 Score = 88.6 bits (218), Expect = 2e-16,   Method: Composition-based stats.
 Identities = 37/152 (24%), Positives = 72/152 (47%), Gaps = 18/152 (11%)

Query: 135 SFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPM 194
           +F ++ I+ +  E++   DD       V +   + +  PE  +  V  + +  V+ R+  
Sbjct: 137 NFTSADIQQKAYEVNASIDD-------VDEEFVRAVLSPEAQKDAVGRQVI--VHNRNAA 187

Query: 195 VKAWILQQSKGICENCGKNAPFYL-NDGNPYLEVHHVIPLSSG-----GADTTDNCVALC 248
             A ++  +   C+    ++ F   + G  ++E HH++P++         D   N V LC
Sbjct: 188 KAAKVVCGANYKCQVDVNHSTFISASSGKAFVEAHHLVPVAKSPDFDVSLDVEPNIVVLC 247

Query: 249 PNCHRELHYSKN--AKELIEMLY-VNINRLQK 277
           PNCHR +HY+++    EL+   Y   IN L++
Sbjct: 248 PNCHRAIHYAESQYKIELLTRFYNQRINELRQ 279


>UniRef50_Q6EME6 Hnh endonuclease n=6 Tax=Enterobacteriaceae RepID=Q6EME6_ECOLX
          Length = 302

 Score = 87.8 bits (216), Expect = 3e-16,   Method: Composition-based stats.
 Identities = 30/157 (19%), Positives = 59/157 (37%), Gaps = 7/157 (4%)

Query: 128 VPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQK 187
           V  I    F+++     +   S      +L       + +      +   K   +E    
Sbjct: 126 VQAIKELDFFSTNESSSIDFYSDNDLITALEESNHFDVTQTFEYSEKAKPKKAAIEVKNG 185

Query: 188 -VYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGN-PYLEVHHVIPLSSG-----GADT 240
             Y R   V    L ++   C+    +  F   +    Y E HH++P+S         D 
Sbjct: 186 LSYPRSKSVSKNALNKADYKCQINCDHPTFRRRNSPLNYTEPHHIVPMSKQDYFENSLDV 245

Query: 241 TDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277
            +N ++LC NCH+++H  K  ++++  +Y     + K
Sbjct: 246 EENIISLCCNCHKQIHLGKGFEDMLRKIYAERKDVLK 282


>UniRef50_B1QVB2 HNH endonuclease domain protein n=2 Tax=Clostridium butyricum
           RepID=B1QVB2_CLOBU
          Length = 409

 Score = 87.8 bits (216), Expect = 3e-16,   Method: Composition-based stats.
 Identities = 29/125 (23%), Positives = 50/125 (40%), Gaps = 9/125 (7%)

Query: 148 LSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGIC 207
           +S+    + +++       K      EG+   ++V +    Y R+P  +   L+     C
Sbjct: 276 ISEMYSKKEIISRYNENDGKSDEKYTEGAMTTIQVNK----YERNPKARKKCLEYYGYKC 331

Query: 208 ENCGKN-APFYLNDGNPYLEVHHVIPLSS----GGADTTDNCVALCPNCHRELHYSKNAK 262
             CG +   FY   G   +EVHH   L+        D   +   +C NCH  +H  K   
Sbjct: 332 CICGFDFEKFYGYIGKNIIEVHHKKALNEIKNTYEVDPIKDLRPVCSNCHTIIHNRKPDY 391

Query: 263 ELIEM 267
           E+ E+
Sbjct: 392 EIEEL 396


>UniRef50_A0YK66 Putative uncharacterized protein n=1 Tax=Lyngbya sp. PCC 8106
           RepID=A0YK66_9CYAN
          Length = 245

 Score = 87.8 bits (216), Expect = 3e-16,   Method: Composition-based stats.
 Identities = 28/95 (29%), Positives = 40/95 (42%)

Query: 164 KLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNP 223
           +     L +          E   K   R   +   +  + KG C+       F   +G+ 
Sbjct: 126 EYYLDQLREDGVLSTSETEEIQIKRVKRYQKITDQLKTKYKGCCQIKDCGFTFIQKNGDN 185

Query: 224 YLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258
           Y E HH++PLS GG+    N V LCPN HR  HY+
Sbjct: 186 YAEAHHLVPLSEGGSQDASNVVILCPNHHRMFHYA 220


>UniRef50_Q67M53 Conserved domain protein n=1 Tax=Symbiobacterium thermophilum
           RepID=Q67M53_SYMTH
          Length = 270

 Score = 87.8 bits (216), Expect = 4e-16,   Method: Composition-based stats.
 Identities = 28/99 (28%), Positives = 42/99 (42%), Gaps = 6/99 (6%)

Query: 182 VERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLS-----S 235
           VE   + Y RDP  +   ++     C  CG N    Y   G  ++EVHHV PL      +
Sbjct: 159 VEYYGRRYERDPENRRRAIEIHGLNCVVCGFNFEEVYGPRGRDFIEVHHVKPLKAFEGVA 218

Query: 236 GGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINR 274
              D   + V +C NCHR +H   ++    + L   +  
Sbjct: 219 QVVDPKVDLVPICANCHRMIHRRHDSVLTPDQLRRIVEE 257


>UniRef50_C7V3C1 Predicted protein n=1 Tax=Enterococcus faecalis T11
           RepID=C7V3C1_ENTFA
          Length = 288

 Score = 87.1 bits (214), Expect = 6e-16,   Method: Composition-based stats.
 Identities = 31/132 (23%), Positives = 51/132 (38%), Gaps = 8/132 (6%)

Query: 149 SQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICE 208
           S+      + ++  ++ I+   S    S +       ++   +   +K   L      CE
Sbjct: 136 SEILPFIEIDDISETRNIELDYSNTAFSTEDTITLPEKERIKKSARLKKECLASHNYQCE 195

Query: 209 NCGKNAPFYL-NDGNPYLEVHHVIPLS-----SGGADTTDNCVALCPNCHRELHYSKNAK 262
               +  F        Y+E HH+IPLS         D T N   LCP CHR +HY K   
Sbjct: 196 INPLHETFISSKTNRNYMETHHIIPLSAQRYYKNKLDCTANLSCLCPTCHRSIHYGKKED 255

Query: 263 E--LIEMLYVNI 272
           +  L++ +Y   
Sbjct: 256 KLPLLKQIYEKH 267


>UniRef50_D0IIJ2 HNH endonuclease n=1 Tax=Vibrio sp. RC586 RepID=D0IIJ2_9VIBR
          Length = 244

 Score = 86.3 bits (212), Expect = 9e-16,   Method: Composition-based stats.
 Identities = 34/138 (24%), Positives = 59/138 (42%), Gaps = 12/138 (8%)

Query: 145 LSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSK 204
           + E SQ             +L +  L   EG+RK + V      Y R+   +A  ++   
Sbjct: 113 IDEFSQKYQTNFQSISYPDELPEDVLI--EGARKQITVN----AYERNHRARAQCIEHYG 166

Query: 205 GICENCGKNA-PFYLNDGNPYLEVHHVIPLSSGGA----DTTDNCVALCPNCHRELHYSK 259
             C  C  N   ++ + G  Y+ VHH + L+  G     +  ++   +CPNCH  LH +K
Sbjct: 167 NSCYICSFNFFEYFGDLGAGYIHVHHQVDLAHVGEAYIVNPIEDLKPVCPNCHAMLHKTK 226

Query: 260 NAKELIEMLYVNINRLQK 277
            A  + E L   ++  ++
Sbjct: 227 PAMSV-EKLKELVSSRKR 243


>UniRef50_Q1YWU8 Putative uncharacterized protein n=3 Tax=Gammaproteobacteria
           RepID=Q1YWU8_PHOPR
          Length = 244

 Score = 86.3 bits (212), Expect = 9e-16,   Method: Composition-based stats.
 Identities = 33/119 (27%), Positives = 54/119 (45%), Gaps = 11/119 (9%)

Query: 154 DESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN 213
           D  L ++   ++ +K+   PEG  K V +      + R+   +   +++    C  C  N
Sbjct: 123 DVELFSIYPDEIDEKSF--PEGMAKKVVIN----SFERNKTARNSCIEEYGLSCSVCEFN 176

Query: 214 -APFYLNDGNPYLEVHHVIPLSSGG----ADTTDNCVALCPNCHRELHYSKNAKELIEM 267
               Y   G  ++ VHHV+ +SS G     D   + V +CPNCH  LH  K A  + E+
Sbjct: 177 FEKAYGELGTGFIHVHHVVDISSIGYAYQVDPKKDLVPVCPNCHAMLHKRKPAFTVQEL 235


>UniRef50_A9B4I7 HNH endonuclease n=1 Tax=Herpetosiphon aurantiacus ATCC 23779
           RepID=A9B4I7_HERA2
          Length = 224

 Score = 86.3 bits (212), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 28/100 (28%), Positives = 42/100 (42%), Gaps = 5/100 (5%)

Query: 180 VEVERLQKVYVRDPMVKAWILQQSKGICENCGKNA-PFYLNDGNPYLEVHHVIPLSS--- 235
            +V+ L   Y R+   +   + Q    C  C  +    Y   G  ++ VHH+ PL+S   
Sbjct: 125 AKVQVLVNQYERNAQARQRGIAQYGTRCLVCELDFVERYGPIGEGFIHVHHIKPLASINA 184

Query: 236 -GGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINR 274
               D  ++   +CPNCH  LH  K     IE L   + R
Sbjct: 185 GYQVDPINDLRPVCPNCHAMLHRGKEQPLTIEELRALLKR 224


>UniRef50_C0CT91 Putative uncharacterized protein n=1 Tax=Clostridium asparagiforme
           DSM 15981 RepID=C0CT91_9CLOT
          Length = 239

 Score = 85.9 bits (211), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 27/94 (28%), Positives = 38/94 (40%), Gaps = 5/94 (5%)

Query: 185 LQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPL----SSGGAD 239
               Y R+   +   +Q     C+ CG +    Y   G  ++E+HH  PL         D
Sbjct: 145 YGTKYERNKKNREMAIQYHGCKCKACGFDFEAVYGEMGKGFIEIHHTKPLYSLQEEIVID 204

Query: 240 TTDNCVALCPNCHRELHYSKNAKELIEMLYVNIN 273
              + V +C NCHR LH +K     IE L   I 
Sbjct: 205 YRTDLVPVCSNCHRILHRNKEKMLSIEELKQLIQ 238


>UniRef50_D2YH85 Putative uncharacterized protein n=1 Tax=Vibrio mimicus VM603
           RepID=D2YH85_VIBMI
          Length = 208

 Score = 85.5 bits (210), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 32/148 (21%), Positives = 59/148 (39%), Gaps = 10/148 (6%)

Query: 133 SDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKV-YVR 191
           SD+ WA        +L    D +      +       +S+P       + +      ++R
Sbjct: 54  SDN-WAP----SRDDLFYSVDGKGSGRWGLRNFEANQVSEPPVDYDGADKQEYTVSRFIR 108

Query: 192 DPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSS--GGADTTDNCVALCP 249
           D  +   + +++   C+ C     F L +G PY E HH+ PL     G D   N + +CP
Sbjct: 109 DSKLSQLVKKKNNYKCQICAF--TFLLPNGKPYAEAHHLKPLGKEHDGPDIEGNLICVCP 166

Query: 250 NCHRELHYSKNAKELIEMLYVNINRLQK 277
           N H  L Y     ++  ++  + + + K
Sbjct: 167 NHHAMLDYCSLKLDVNAIVKNSKHEIMK 194


>UniRef50_Q5YRW6 Putative endonuclease n=1 Tax=Nocardia farcinica RepID=Q5YRW6_NOCFA
          Length = 123

 Score = 85.5 bits (210), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 11/93 (11%)

Query: 190 VRDPMVKAWILQ-----QSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSSGGADT--T 241
            R+P ++   L       S+  CE CG +    Y   G  Y+E HH++PL   G      
Sbjct: 17  ERNPKLRKAKLAEFRRVHSRVFCEVCGFDFEAVYGERGAGYIECHHIVPLHVSGETVTKL 76

Query: 242 DNCVALCPNCHRELHYSKN---AKELIEMLYVN 271
            + V LC NCHR +H+       +EL E++ V+
Sbjct: 77  SDLVLLCSNCHRMIHHGSRWLSPEELREVVQVS 109


>UniRef50_Q46AN8 Putative uncharacterized protein n=1 Tax=Methanosarcina barkeri
           str. Fusaro RepID=Q46AN8_METBF
          Length = 268

 Score = 84.8 bits (208), Expect = 3e-15,   Method: Composition-based stats.
 Identities = 29/135 (21%), Positives = 54/135 (40%), Gaps = 9/135 (6%)

Query: 140 IIRGELSELSQPTDDESLLNMRVSKLIKKTLSQP------EGSRKPVEVERLQKVYVRDP 193
           I+      +S     ++ ++    +       +       +    P   E +  +  R  
Sbjct: 120 ILNWISEAVSTYVSSKTAISEEFREGKTLDYDELIQKLDIKYRNTPEFKETITGLIQRPS 179

Query: 194 MVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTT--DNCVALCPNC 251
           ++   I ++    C  CG    F   +G  Y EVHH+I L+    +T    N + +CP C
Sbjct: 180 LLSNAIKEKYGYKCMICGYPG-FLKKNGEKYAEVHHMIELNQKAPETLQSWNLLVVCPLC 238

Query: 252 HRELHYSKNAKELIE 266
           HR+LHY+    E ++
Sbjct: 239 HRKLHYADVKSEFLD 253


>UniRef50_C1SP87 Predicted restriction endonuclease n=1 Tax=Denitrovibrio
           acetiphilus DSM 12809 RepID=C1SP87_9BACT
          Length = 244

 Score = 84.8 bits (208), Expect = 3e-15,   Method: Composition-based stats.
 Identities = 30/107 (28%), Positives = 42/107 (39%), Gaps = 10/107 (9%)

Query: 173 PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVI 231
            EG++  V V     +Y RD   +   L+     C  CG N    Y   G  ++  HH+ 
Sbjct: 140 YEGAKTTVTVN----IYERDHDARTKCLESQGCTCSVCGFNFEQAYGLMGIDFIHTHHIT 195

Query: 232 PLSS----GGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINR 274
           P S        D   + V LCPNCH  +H       + E L   + R
Sbjct: 196 PPSEIDKNYIPDPAKDLVPLCPNCHAMIHRKSPPYTI-EQLRAKLRR 241


>UniRef50_D2YGR3 Putative uncharacterized protein n=1 Tax=Vibrio mimicus VM603
           RepID=D2YGR3_VIBMI
          Length = 262

 Score = 84.4 bits (207), Expect = 4e-15,   Method: Composition-based stats.
 Identities = 23/103 (22%), Positives = 39/103 (37%), Gaps = 6/103 (5%)

Query: 177 RKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSS 235
           ++      +     R+P  +   ++     C  C  N    Y   G  ++ VHH   L+S
Sbjct: 159 KEGARFSVMSTAIERNPAARKKCIEHYGYTCAACDINMESKYGRIGKKFIHVHHRTDLAS 218

Query: 236 -GGA---DTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINR 274
             G    D   + + LCPNCH  +H  +     +E L   +  
Sbjct: 219 IQGIHRVDPLRDLIPLCPNCHAMIH-KEKPAMPLENLRAILRE 260


>UniRef50_B0A7V0 Putative uncharacterized protein n=1 Tax=Clostridium bartlettii DSM
           16795 RepID=B0A7V0_9CLOT
          Length = 254

 Score = 83.6 bits (205), Expect = 7e-15,   Method: Composition-based stats.
 Identities = 33/152 (21%), Positives = 54/152 (35%), Gaps = 15/152 (9%)

Query: 130 GIYSDSFWASIIRGELSELS--QPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQK 187
           G  S  F          E       +DES+  +   ++  +     EG RK    +    
Sbjct: 106 GYPSIKFTKIFGNTYEVEFIGLDLLNDESINPLETIEIENRV----EGKRK----KIYTT 157

Query: 188 VYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPL----SSGGADTTD 242
            Y R    +   ++     C  C  +    Y   G  ++EVHH  PL         +  +
Sbjct: 158 KYERSYKNREKAIKIHGTRCMVCDFDFEEAYGELGKDFIEVHHTKPLYSLEEEIEINPEE 217

Query: 243 NCVALCPNCHRELHYSKNAKELIEMLYVNINR 274
           + V LC NCHR +H  ++    +E L   +  
Sbjct: 218 DLVCLCSNCHRMIHRRRDKILTVEELKEIMEE 249


>UniRef50_B0KIU7 HNH endonuclease n=1 Tax=Pseudomonas putida GB-1 RepID=B0KIU7_PSEPG
          Length = 281

 Score = 83.6 bits (205), Expect = 7e-15,   Method: Composition-based stats.
 Identities = 30/111 (27%), Positives = 46/111 (41%), Gaps = 9/111 (8%)

Query: 162 VSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLND 220
             +  ++ +  PEG++  +EV R    Y RD   +A  L      C+ C  +    Y   
Sbjct: 165 AEEEFREVIGLPEGAKVRIEVNR----YERDRRNRAAALAIHGYSCKACDLDMGGRYGPV 220

Query: 221 GNPYLEVHHVIPLSSGG----ADTTDNCVALCPNCHRELHYSKNAKELIEM 267
               +EVHH  P+S  G     D   + + LCPNCH   H       + E+
Sbjct: 221 AAGLIEVHHTTPVSELGLGYIIDPKTDLIPLCPNCHSVSHRRSPPFSVAEL 271


>UniRef50_C3AW04 Putative uncharacterized protein n=1 Tax=Bacillus mycoides Rock1-4
           RepID=C3AW04_BACMY
          Length = 212

 Score = 83.6 bits (205), Expect = 7e-15,   Method: Composition-based stats.
 Identities = 29/110 (26%), Positives = 45/110 (40%), Gaps = 10/110 (9%)

Query: 168 KTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQ----SKGI--CENCGKNA-PFYLND 220
           + +   E   +  ++ R    Y R+  V     +       G   CE CG +    Y   
Sbjct: 98  ELIDLEEEFSEGKQILRTHLSYERNNKVIKSAKEHFKQQHGGKLFCEICGFDFYKTYGEL 157

Query: 221 GNPYLEVHHVIPLSS---GGADTTDNCVALCPNCHRELHYSKNAKELIEM 267
           G  Y+E HH IP+S    G     ++ + +C NCHR LH  K    + E+
Sbjct: 158 GKDYIEGHHTIPVSQLKEGEKTKIEDIIMVCSNCHRMLHRRKPWLSIAEL 207


>UniRef50_C3IFK0 5-methylcytosine-specific restriction enzyme A n=5 Tax=Bacteria
           RepID=C3IFK0_BACTU
          Length = 260

 Score = 82.4 bits (202), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 31/135 (22%), Positives = 53/135 (39%), Gaps = 10/135 (7%)

Query: 143 GELSELSQPTDDESLLNMRVSKLIK-----KTLSQPEGSRKPVEVERLQKVYVRDPMVKA 197
           G++ E         L  + +   +      + +  PE   +    +    VY R+ + + 
Sbjct: 116 GDVKEYDDTKPVRILWKINIENEMNLLKLPEKIIDPEKYIEGATKQINVNVYERNSVARM 175

Query: 198 WILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPL----SSGGADTTDNCVALCPNCH 252
             ++     C  CG N    Y + G  ++ VHH+I L         D  ++   +CPNCH
Sbjct: 176 KCIEHYGVNCIICGFNFEEIYGSVGKEFIHVHHLIELREINEQYEVDPIEDLRPVCPNCH 235

Query: 253 RELHYSKNAKELIEM 267
             LH  K A  + EM
Sbjct: 236 AILHKRKPAYSIKEM 250


>UniRef50_C3LV13 HNH endonuclease n=13 Tax=Vibrio RepID=C3LV13_VIBCM
          Length = 234

 Score = 82.1 bits (201), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 46/212 (21%), Positives = 76/212 (35%), Gaps = 35/212 (16%)

Query: 75  LDERKIHPG-----EYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEIPSGN--RTKRILIN 127
            DE    PG     E+ +LI N+    RLK    Q   + TG  +I S +    ++ L  
Sbjct: 45  FDESWKGPGRKQSLEHISLIQNN--GYRLKTFPMQYDQTETGTAKIKSFDWILEEKHLAG 102

Query: 128 VPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQK 187
           V G+                 S+  D  S+            +  PE   +    E    
Sbjct: 103 VDGL-----------WYALNYSESVDITSIEE----------VVHPETYIEGATKEISVN 141

Query: 188 VYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLS----SGGADTTD 242
            Y R+P  +A  +      C  C  +    Y + G  ++ VHH + L+        D   
Sbjct: 142 AYERNPDARAKCILHYGCKCYVCKFDFQEVYGDIGKGFIHVHHEVSLAEIKKEYSVDPIK 201

Query: 243 NCVALCPNCHRELHYSKNAKELIEMLYVNINR 274
           +   LCPNCH  +H +     +  ++ +  +R
Sbjct: 202 DLKPLCPNCHGIIHRTHPPISVDSLINLLRSR 233


>UniRef50_C8TQ55 Predicted endonuclease n=10 Tax=Enterobacteriaceae
           RepID=C8TQ55_ECO26
          Length = 216

 Score = 82.1 bits (201), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 33/137 (24%), Positives = 53/137 (38%), Gaps = 10/137 (7%)

Query: 130 GIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVY 189
           GI S      I +G    L +         +   +L  +  +  EG+   V V R    Y
Sbjct: 69  GIKSKCVKLLIEQGFHIHLDKAAAAPIADVLFPDELPSQE-TYLEGAAIKVTVNR----Y 123

Query: 190 VRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLS----SGGADTTDNC 244
            RD   +   ++     C  CG +    Y +    ++ VHH++PLS        D  ++ 
Sbjct: 124 ERDKKARDKAVEHHGCQCNVCGVDLVKIYGDIAEGFIHVHHLVPLSAIKEDYQLDPVNDL 183

Query: 245 VALCPNCHRELHYSKNA 261
           + + PNCH  LH  K  
Sbjct: 184 LPVYPNCHAMLHRRKPP 200


>UniRef50_A0KZG4 HNH endonuclease n=1 Tax=Shewanella sp. ANA-3 RepID=A0KZG4_SHESA
          Length = 253

 Score = 81.7 bits (200), Expect = 3e-14,   Method: Composition-based stats.
 Identities = 24/95 (25%), Positives = 43/95 (45%), Gaps = 8/95 (8%)

Query: 187 KVYVRDPMVKAWILQQSKGICENCGKNAPF-YLNDGNPYLEVHHVIPLS----SGGADTT 241
            V+ R+P  +   ++     C  CG +    Y + G  ++ VHH + L+        +  
Sbjct: 158 SVHEREPAARRACIEHYGVSCHVCGFDFEHAYGDIGKGFIHVHHRVDLALVSNRREVNPI 217

Query: 242 DNCVALCPNCHRELHYSKNA---KELIEMLYVNIN 273
           ++ + +CPNCH  LH    A    +L E+L  N+ 
Sbjct: 218 EDLIPVCPNCHAMLHTETPAMAVDKLKELLKQNLQ 252


>UniRef50_C5QAR7 HNH endonuclease n=5 Tax=Firmicutes RepID=C5QAR7_STAEP
          Length = 123

 Score = 81.7 bits (200), Expect = 3e-14,   Method: Composition-based stats.
 Identities = 21/95 (22%), Positives = 42/95 (44%), Gaps = 5/95 (5%)

Query: 184 RLQKVYVRDPMVKAWILQQSKGICENCGKNAPF-YLNDGNPYLEVHHVIPL----SSGGA 238
           +    Y R+  ++   ++     C+ CG +    Y + G  ++E+HH+ P+         
Sbjct: 25  QYGIKYERNQALRNEAIKIHGTTCKVCGFDFKAKYGDLGEGFIEIHHLKPMFSIKREIKV 84

Query: 239 DTTDNCVALCPNCHRELHYSKNAKELIEMLYVNIN 273
           +   + V LC NCH+ +H +      I+ L   +N
Sbjct: 85  NPQKDLVPLCSNCHKMIHRNTKKPLTIKELTKIVN 119


>UniRef50_A0JWW4 HNH endonuclease n=1 Tax=Arthrobacter sp. FB24 RepID=A0JWW4_ARTS2
          Length = 297

 Score = 81.3 bits (199), Expect = 3e-14,   Method: Composition-based stats.
 Identities = 28/101 (27%), Positives = 40/101 (39%), Gaps = 9/101 (8%)

Query: 173 PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPF-YLNDGNPYLEVHHVI 231
           P  +   VEV R    Y R+P  +   +      C  CG +    Y + G  +++VHH  
Sbjct: 158 PAWAVSKVEVNR----YERNPEARRACIAHYGTSCAACGFSFEIAYGDAGREFIDVHHTT 213

Query: 232 PLS----SGGADTTDNCVALCPNCHRELHYSKNAKELIEML 268
           P+S    S   D   + V LC NCH   H        +  L
Sbjct: 214 PVSLLDSSYRLDPVTDLVPLCSNCHAMAHLGVTTPRTLPEL 254


>UniRef50_C3IFK4 5-methylcytosine-specific restriction enzyme A n=1 Tax=Bacillus
           thuringiensis IBL 4222 RepID=C3IFK4_BACTU
          Length = 328

 Score = 81.3 bits (199), Expect = 4e-14,   Method: Composition-based stats.
 Identities = 41/176 (23%), Positives = 66/176 (37%), Gaps = 18/176 (10%)

Query: 110 TGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKT 169
           TG K +   N     L N+     D     +   E +   Q      +    V  +I + 
Sbjct: 146 TGEKVLNVTNPRSIFLTNISESLRDLIIEILRNPEANYQYQ------VEQENVGSVIIED 199

Query: 170 LSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLN-DGNPYLEVH 228
           + +   S+   E       Y RD       +  +   CE    +  F        Y+E H
Sbjct: 200 IPKNVPSKSKGE---GSGAYKRDFKTAKNAIVLANYKCEIDLNHEYFISKVTKRNYVEAH 256

Query: 229 HVIPLS-----SGGADTTDNCVALCPNCHRELHYSKNA--KELIEMLY-VNINRLQ 276
           H+IP+          D   N ++LC  CH++LH+++    + LI+ LY   INRL 
Sbjct: 257 HLIPMGFQDDFQKSIDVEANIISLCAYCHKKLHHAEYKVIEPLIKKLYDARINRLN 312


>UniRef50_C3L8D2 Putative uncharacterized protein n=6 Tax=Bacillus anthracis
           RepID=C3L8D2_BACAC
          Length = 211

 Score = 80.9 bits (198), Expect = 4e-14,   Method: Composition-based stats.
 Identities = 32/117 (27%), Positives = 49/117 (41%), Gaps = 11/117 (9%)

Query: 168 KTLSQPEGSRKPVEVERLQKVYVRDPMVKAWIL----QQSKGI--CENCGKNA-PFYLND 220
           + +   E   +  ++ R    Y R+  V         Q+  G   CE CG +    Y   
Sbjct: 96  ELIDLEEEFSEGKQILRTHLSYERNNKVIKRAKEHFKQKHGGKIFCEICGFDFHKIYGEL 155

Query: 221 GNPYLEVHHVIPLSS---GGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINR 274
           G  ++E HH IP+S    G     ++ + +C NCHR LH +K      E LY  I +
Sbjct: 156 GKDFIEGHHTIPVSQLKEGEKTRIEDIIMVCSNCHRMLHRTKFVLT-KEDLYSIIQK 211


>UniRef50_A1F1U9 HNH endonuclease domain protein n=1 Tax=Vibrio cholerae 2740-80
           RepID=A1F1U9_VIBCH
          Length = 210

 Score = 80.5 bits (197), Expect = 5e-14,   Method: Composition-based stats.
 Identities = 37/148 (25%), Positives = 58/148 (39%), Gaps = 20/148 (13%)

Query: 137 WASIIRGELSELSQPTDD-ESLLNMRVS---------------KLIKKTLSQPEGSRKPV 180
           W ++IR  + +LS  +D  ++  ++  S                   K    P G+++P 
Sbjct: 39  WKAVIRRRIQDLSSDSDGFKNGQDLFYSVNGLGGGMWGLRNKLAYTPKAADLPTGTKEPE 98

Query: 181 EVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLS--SGGA 238
                    +RD  +   +       C+ CG      L +G  Y E HH+IPL     G+
Sbjct: 99  REYTTTYRVLRDTNLARKLKLLYNNSCQICGLQ--IQLPNGKLYSEAHHIIPLGNPHHGS 156

Query: 239 DTTDNCVALCPNCHRELHYSKNAKELIE 266
           DT +N + LCPN H    Y      L E
Sbjct: 157 DTPENIIVLCPNHHVMCDYGAIELSLKE 184


>UniRef50_A7C7H9 HNH endonuclease n=2 Tax=Gammaproteobacteria RepID=A7C7H9_9GAMM
          Length = 101

 Score = 80.1 bits (196), Expect = 7e-14,   Method: Composition-based stats.
 Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 5/74 (6%)

Query: 199 ILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSSGGA----DTTDNCVALCPNCHR 253
            +++    C  C  +   FY + G  Y+ VHH+IPL+        D   + V LCPNCH 
Sbjct: 11  CIEKYGHKCVVCSFDFEKFYGSIGKKYIHVHHIIPLAEIKKEYQLDPLKDLVPLCPNCHA 70

Query: 254 ELHYSKNAKELIEM 267
            +H ++    + ++
Sbjct: 71  MIHRTQPTLTIQQL 84


>UniRef50_Q5L3M3 Hnh endonuclease n=1 Tax=Geobacillus kaustophilus
           RepID=Q5L3M3_GEOKA
          Length = 243

 Score = 79.7 bits (195), Expect = 9e-14,   Method: Composition-based stats.
 Identities = 30/126 (23%), Positives = 52/126 (41%), Gaps = 11/126 (8%)

Query: 146 SELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKG 205
            E+    D E + ++ VS+    +L+  EG+ + V V      Y R+   +   +     
Sbjct: 116 EEIFGQNDTEFVYSVEVSREDVSSLT--EGTVRQVFVNH----YERNRRARRICINHYGS 169

Query: 206 ICENCGKN-APFYLNDGNPYLEVHHVIPLSS----GGADTTDNCVALCPNCHRELHYSKN 260
            C  CG +    Y   G   + +HH++PLS        D   +   +CPNCH  +H  + 
Sbjct: 170 KCVVCGFDFEKTYGPIGKDKIHIHHLVPLSEIQKEYEVDPIRDLRPVCPNCHFIIHSKRE 229

Query: 261 AKELIE 266
              + E
Sbjct: 230 PFTIEE 235


>UniRef50_O83027 Disrupted by IS8301 insertion n=1 Tax=Deinococcus radiodurans
           RepID=O83027_DEIRA
          Length = 241

 Score = 79.7 bits (195), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 21/104 (20%), Positives = 40/104 (38%), Gaps = 5/104 (4%)

Query: 169 TLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEV 227
           +  +     +    +     Y R+   +A  +     +C  C  +    Y      Y++V
Sbjct: 129 SAEEARTFVEGATRQIFVNAYERNAGARAACIAHFGTVCRVCETDLVAIYGEVARGYIQV 188

Query: 228 HHVIPLSSGG----ADTTDNCVALCPNCHRELHYSKNAKELIEM 267
           HH+  L+  G     +   + + +CPNCH  LH  + A    E+
Sbjct: 189 HHLRSLAEVGRQYEVNPLTDLIPVCPNCHAMLHQRRPAYTPEEL 232


>UniRef50_A3WCW2 HNH endonuclease n=1 Tax=Erythrobacter sp. NAP1 RepID=A3WCW2_9SPHN
          Length = 207

 Score = 79.4 bits (194), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 36/182 (19%), Positives = 72/182 (39%), Gaps = 23/182 (12%)

Query: 98  LKMCGYQAY---FSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELS-ELSQPTD 153
           +KM  +++    F   G+  + SG + ++++           W   ++  ++ +L     
Sbjct: 25  MKMMNFRSIDPAFKAQGKAGMKSGGKLEKVV-----------WYKFVKDPVALKLEADRI 73

Query: 154 DESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWIL---QQSKGI-CEN 209
            +++    V  L            +   V RL K Y RD  +    +   +++  + CE 
Sbjct: 74  RKAVEKADVESLAALPNEDEVEGEEGGVVMRLHKRYERDRSLSRKKIVSAKKAGSVECEV 133

Query: 210 CGKN-APFYLNDGNPYLEVHHVIPLS---SGGADTTDNCVALCPNCHRELHYSKNAKELI 265
           C  +    +   G+ ++EVHH+ P+     G      +   LC NCHR  H  +    L 
Sbjct: 134 CEFDFEAAFGELGDGFIEVHHLKPVHTLGKGSKTRLKDLALLCANCHRMAHRKRIPLSLD 193

Query: 266 EM 267
           E+
Sbjct: 194 EL 195


>UniRef50_A5W5D0 HNH endonuclease n=4 Tax=Gammaproteobacteria RepID=A5W5D0_PSEP1
          Length = 268

 Score = 79.4 bits (194), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 31/151 (20%), Positives = 61/151 (40%), Gaps = 9/151 (5%)

Query: 128 VPGIYSDSFWASIIRG-ELSELSQPTDDESLLNMRVSKLIKKTLSQP---EGSRKPVEVE 183
           +PG  + ++W   +R    S+         LL+ R+   + ++   P   E + +  +  
Sbjct: 106 IPGSRASNYWRDGVRLISQSDYDAILSHAKLLDPRLDTALPQSEDDPITFESANEGSKTS 165

Query: 184 RLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSSGG----A 238
                Y R   ++   +      C+ CG +    Y      ++ VHHV+P+S  G     
Sbjct: 166 YFGTRYERRKDLRMKAIAIHGLDCKACGFDFEQAYGEHAKGFIHVHHVVPISKFGGEQAV 225

Query: 239 DTTDNCVALCPNCHRELHYSKNAKELIEMLY 269
           +   + V LC NCH  +H  ++    ++ L 
Sbjct: 226 NPETDLVTLCANCHAVVHRKRDMTLSVDELK 256


>UniRef50_Q3EQP7 5-methylcytosine-specific restriction enzyme A n=1 Tax=Bacillus
           thuringiensis serovar israelensis ATCC 35646
           RepID=Q3EQP7_BACTI
          Length = 186

 Score = 79.0 bits (193), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 41/176 (23%), Positives = 66/176 (37%), Gaps = 18/176 (10%)

Query: 110 TGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKT 169
           TG K +   N     L N+     D     +   E +   Q      +    V  +I + 
Sbjct: 4   TGEKVLNVTNPRSIFLTNISESLRDLIIEILRNPEANYQYQ------VEQENVGSVIIED 57

Query: 170 LSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLN-DGNPYLEVH 228
           + +   S+   E       Y RD       +  +   CE    +  F        Y+E H
Sbjct: 58  IPKNVPSKSKGE---GSGAYKRDFKTAKNAIVLANYKCEIDLNHEYFISKVTKRNYVEAH 114

Query: 229 HVIPLS-----SGGADTTDNCVALCPNCHRELHYSKNA--KELIEMLY-VNINRLQ 276
           H+IP+          D   N ++LC  CH++LH+++    + LI+ LY   INRL 
Sbjct: 115 HLIPMGFQDDFQKSIDVEANIISLCAYCHKKLHHAEYKVIEPLIKKLYDARINRLN 170


>UniRef50_B0KGB9 Restriction endonuclease-like protein n=1 Tax=Pseudomonas putida
           GB-1 RepID=B0KGB9_PSEPG
          Length = 314

 Score = 78.6 bits (192), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 29/105 (27%), Positives = 45/105 (42%), Gaps = 9/105 (8%)

Query: 168 KTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPF-YLNDGNPYLE 226
           ++LS  EG+ + VE+ R    Y R+P  +   +      C+ CG N    Y       + 
Sbjct: 198 ESLSLLEGAVRTVELTR----YERNPTARRLCIAHYGPTCQACGLNYEIKYGPIAVDLIH 253

Query: 227 VHHVIPLSSGGA----DTTDNCVALCPNCHRELHYSKNAKELIEM 267
           VHH+ PL++ G     D   + V LC  CH  +H         E+
Sbjct: 254 VHHLTPLAAIGESYQVDPIRDLVPLCATCHHVVHAKTPPYTPEEL 298


>UniRef50_D1XF45 HNH endonuclease n=3 Tax=Streptomyces RepID=D1XF45_9ACTO
          Length = 354

 Score = 77.8 bits (190), Expect = 3e-13,   Method: Composition-based stats.
 Identities = 32/125 (25%), Positives = 49/125 (39%), Gaps = 12/125 (9%)

Query: 151 PTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVK----AWILQQSKGI 206
            T D         +      S PEG      + R  +   R+  ++    A +LQ+   +
Sbjct: 202 ATGDLQSFAPAEEEEFGDDFSAPEGR----LLMRRHRARERNKGLRKKKIASVLQRGGQL 257

Query: 207 -CENCGKN-APFYLNDGNPYLEVHHVIPLSSGGADT--TDNCVALCPNCHRELHYSKNAK 262
            CE CG +    Y + G  Y+E HHV+PL   G       +   +C NCHR +H      
Sbjct: 258 ACEACGFDFEKIYGDRGAGYIECHHVLPLHVAGEGRTKLGDLALICANCHRMIHRRAPWP 317

Query: 263 ELIEM 267
              E+
Sbjct: 318 TPGEL 322


>UniRef50_D0S0J8 Hnh endonuclease n=1 Tax=Acinetobacter calcoaceticus RUH2202
           RepID=D0S0J8_ACICA
          Length = 208

 Score = 77.4 bits (189), Expect = 5e-13,   Method: Composition-based stats.
 Identities = 30/106 (28%), Positives = 45/106 (42%), Gaps = 12/106 (11%)

Query: 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIP 232
           EG+ K + V      Y R+   +   L+     C  C  +    Y + G   + VHH++ 
Sbjct: 104 EGAAKKIVVN----AYERNKEARKKCLEFYGYQCVVCNFDFEKTYGSVGKNCIHVHHLVE 159

Query: 233 LSSGGA----DTTDNCVALCPNCHRELHYSKNA---KELIEMLYVN 271
           +SS G     D   +   +CPNCH  +H  K A    E+  ML  N
Sbjct: 160 ISSIGKKYIVDPIKDMAPVCPNCHFIIHQHKPAFSIDEVRAMLKSN 205


>UniRef50_Q477P3 HNH endonuclease n=1 Tax=Ralstonia eutropha JMP134
           RepID=Q477P3_RALEJ
          Length = 249

 Score = 77.1 bits (188), Expect = 5e-13,   Method: Composition-based stats.
 Identities = 36/133 (27%), Positives = 54/133 (40%), Gaps = 18/133 (13%)

Query: 139 SIIRGELSELSQP---TDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMV 195
           +++RG   +         DE L      +L+ +T    E SRK V+ +R Q V+      
Sbjct: 118 ALLRGLTDDAFADLPEYPDEDLTEAPEGRLLTRTHLSRERSRKLVKAKREQ-VWE----- 171

Query: 196 KAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLS---SGGADTTDNCVALCPNC 251
                Q  K  CE C  + A  Y   G  ++E HH  PLS           +   +C NC
Sbjct: 172 -----QTGKLRCEVCAFDFAKAYGEHGAGFIECHHTKPLSTLPENSKTHIGDLALVCANC 226

Query: 252 HRELHYSKNAKEL 264
           HR LH  +   ++
Sbjct: 227 HRMLHRGEVWPDV 239


>UniRef50_B2IKM5 HNH endonuclease n=1 Tax=Beijerinckia indica subsp. indica ATCC
           9039 RepID=B2IKM5_BEII9
          Length = 285

 Score = 77.1 bits (188), Expect = 7e-13,   Method: Composition-based stats.
 Identities = 24/92 (26%), Positives = 37/92 (40%), Gaps = 4/92 (4%)

Query: 190 VRDPMVKAWILQQSKGICENCGKNA-PFYLNDGNPYLEVHHVIPLSS-GGA--DTTDNCV 245
            R   +     ++ +  C+ C  +    Y   G  + E HH +PLS   G   +  D+ V
Sbjct: 191 ERKAALARECKKRDRYRCQICNFHFVERYGLLGENFAEAHHKVPLSKLDGEVKNCVDDLV 250

Query: 246 ALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277
            +C NCHR LH  +     I  L      + K
Sbjct: 251 TVCANCHRMLHRLEGKPTDIVKLRRIFKHVGK 282


>UniRef50_A9B5H7 HNH endonuclease n=1 Tax=Herpetosiphon aurantiacus ATCC 23779
           RepID=A9B5H7_HERA2
          Length = 223

 Score = 76.7 bits (187), Expect = 8e-13,   Method: Composition-based stats.
 Identities = 25/99 (25%), Positives = 38/99 (38%), Gaps = 4/99 (4%)

Query: 171 SQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHV 230
           ++P G+R             RD  V +W+       C+ CG      +     Y E HH+
Sbjct: 104 NKPAGNRLTRRTINTIDRIQRDTKVSSWVKYIYNYACQICG--IRLQIGQDKFYAECHHI 161

Query: 231 IPLS--SGGADTTDNCVALCPNCHRELHYSKNAKELIEM 267
            PL     G D  +N + +CPN H  L Y     +   +
Sbjct: 162 RPLGGVHQGEDIVENVLCVCPNHHALLDYGAIRIDFSTL 200


>UniRef50_UPI0001BC7063 hypothetical protein VparAQ_18636 n=1 Tax=Vibrio parahaemolyticus
           AQ4037 RepID=UPI0001BC7063
          Length = 300

 Score = 76.3 bits (186), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 32/135 (23%), Positives = 52/135 (38%), Gaps = 10/135 (7%)

Query: 143 GELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQ 202
           G +S L Q       L     +         EG R+     R    + R+  +      +
Sbjct: 166 GYVSHLLQKPYVIDDLGDYEIRENSPEQEYAEGERQV----REASYFKRNSKLVKDAKAE 221

Query: 203 SKGICENCGKN-APFYLND-GNPYLEVHHVIPLSSGGAD---TTDNCVALCPNCHRELHY 257
              IC+ C  +    Y  + G  ++E HH  PL     +   T ++   +C NCHR LH 
Sbjct: 222 FGFICQVCDFDFESVYGKELGAGFIECHHKNPLHEKDENYISTLNDVCVVCSNCHRMLHR 281

Query: 258 SKNAKELIEMLYVNI 272
           +K A +  E+L   +
Sbjct: 282 TKPAMKP-EILKAKL 295


>UniRef50_A6GA77 HNH endonuclease n=1 Tax=Plesiocystis pacifica SIR-1
           RepID=A6GA77_9DELT
          Length = 335

 Score = 76.3 bits (186), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 31/145 (21%), Positives = 58/145 (40%), Gaps = 12/145 (8%)

Query: 145 LSELSQPTDDESLLNMRVS--KLIKKTLSQPEGS-RKPVEVERLQKVYVRDPMVKAWILQ 201
               S+P    ++    V+   L+ + + + E    +   + RL + Y R   +     +
Sbjct: 190 DDFASEPYKLRAMAEAIVAGHALVSERVDEDEDEYAEGKVLYRLHRRYERSAKLVRDAKR 249

Query: 202 QS-----KGICENCGKN-APFYLNDGNPYLEVHHVIPLSSGG---ADTTDNCVALCPNCH 252
           ++     +  CE C  + +  Y   G  Y+E HH +P+S          ++   +C NCH
Sbjct: 250 RALAKHGRLACECCDFDFSEVYGALGEGYIEAHHRVPVSQMSGKKKAKVEDLAMVCANCH 309

Query: 253 RELHYSKNAKELIEMLYVNINRLQK 277
           R LH SK    +  +    + R  K
Sbjct: 310 RMLHRSKPLMSVEALRERVLGRRSK 334


>UniRef50_Q39IU3 Putative uncharacterized protein n=1 Tax=Burkholderia sp. 383
           RepID=Q39IU3_BURS3
          Length = 122

 Score = 75.9 bits (185), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 20/56 (35%), Positives = 33/56 (58%)

Query: 196 KAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNC 251
           +  +L +++  CE CG  A +   DG P+L+ HH+  L+   +DT  N  ++CPNC
Sbjct: 20  RLSLLDRAETTCEACGHPATYSGADGFPFLDTHHLRKLTDSESDTVTNAFSVCPNC 75


>UniRef50_Q6MJA3 Putative membrane protein n=1 Tax=Bdellovibrio bacteriovorus
           RepID=Q6MJA3_BDEBA
          Length = 140

 Score = 75.5 bits (184), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 30/95 (31%), Positives = 47/95 (49%), Gaps = 7/95 (7%)

Query: 176 SRKPVEVERLQKVYVRDPMVKAWILQQ-SKGICENCGKNAPFYLNDGNPYLEVHHVIPLS 234
           S  P E ++ +K   R+     W  Q+  KG+C +CGK   F   D    L + H+IP++
Sbjct: 34  SAAPPEHQKREKAKARELRQSQWWKQELGKGLCYHCGKR--FKPAD----LTMDHLIPIA 87

Query: 235 SGGADTTDNCVALCPNCHRELHYSKNAKELIEMLY 269
            GG    +NCV  C +C+ +  Y   A+  +E L 
Sbjct: 88  RGGKSNKNNCVPSCKDCNSKKGYKTRAEMALEELK 122


>UniRef50_Q3EYN0 HNH endonuclease family protein n=1 Tax=Bacillus thuringiensis
           serovar israelensis ATCC 35646 RepID=Q3EYN0_BACTI
          Length = 422

 Score = 75.1 bits (183), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 31/130 (23%), Positives = 58/130 (44%), Gaps = 9/130 (6%)

Query: 140 IIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKP-----VEVERLQKVYVRDPM 194
           ++ GE     Q ++DE L  + + + + K ++  +          V  + ++     DP+
Sbjct: 214 VVEGEEKPEVQLSNDEVLAILEMGEALDKEINPDDFGSMGDMFGEVTHQDVKNRKPVDPI 273

Query: 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254
           +K   L +    C  CG     +L+     +  HH++P+ +GG DT  N + LC +CH  
Sbjct: 274 IKQQTLARDDYRCRCCGTGGKAFLST----IIFHHIVPVHAGGPDTVANGLTLCDSCHIT 329

Query: 255 LHYSKNAKEL 264
           LH  +    L
Sbjct: 330 LHVIERNGRL 339


>UniRef50_C3GU40 HNH endonuclease n=2 Tax=Bacillus thuringiensis RepID=C3GU40_BACTU
          Length = 622

 Score = 75.1 bits (183), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 31/130 (23%), Positives = 58/130 (44%), Gaps = 9/130 (6%)

Query: 140 IIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKP-----VEVERLQKVYVRDPM 194
           ++ GE     Q ++DE L  + + + + K ++  +          V  + ++     DP+
Sbjct: 414 VVEGEEKPEVQLSNDEVLAILEMGEALDKEINPDDFGSMGDMFGEVTHQDVKNRKPVDPI 473

Query: 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254
           +K   L +    C  CG     +L+     +  HH++P+ +GG DT  N + LC +CH  
Sbjct: 474 IKQQTLARDDYRCRCCGTGGKAFLST----IIFHHIVPVHAGGPDTVANGLTLCDSCHIT 529

Query: 255 LHYSKNAKEL 264
           LH  +    L
Sbjct: 530 LHVIERNGRL 539


>UniRef50_B1QVB3 HNH endonuclease domain protein n=2 Tax=Clostridium butyricum
           RepID=B1QVB3_CLOBU
          Length = 492

 Score = 74.4 bits (181), Expect = 4e-12,   Method: Composition-based stats.
 Identities = 30/119 (25%), Positives = 52/119 (43%), Gaps = 15/119 (12%)

Query: 159 NMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGI------CENCGK 212
            +  S  I +  +  EG++K + V      Y R+   +   ++  K I      CE CG 
Sbjct: 369 QIFPSDEIDEEYTLIEGAKKQIVVN----AYERNVKARNECIEYYKKINNGQVKCEICGF 424

Query: 213 N-APFYLNDGNPYLEVHHVIPLSSGG----ADTTDNCVALCPNCHRELHYSKNAKELIE 266
           N    Y N     + +HH++ ++  G     +  ++ + +CPNCH  LH  K A +  E
Sbjct: 425 NFGDIYGNQFRDKINIHHIVEIAQIGQGYIINPKEDLIPVCPNCHYILHCKKPAYKPEE 483


>UniRef50_C2NAK2 HNH endonuclease n=1 Tax=Bacillus cereus ATCC 10876
           RepID=C2NAK2_BACCE
          Length = 381

 Score = 74.4 bits (181), Expect = 4e-12,   Method: Composition-based stats.
 Identities = 28/131 (21%), Positives = 54/131 (41%), Gaps = 10/131 (7%)

Query: 139 SIIRGELSELSQPTDDESLLNMRVSKLIKKT-LSQPEGSRKPVEVERLQKVYVRDPMVKA 197
           S+++ E+ + +   D    L+     +   T + + +   +  E  RL +   R+  +  
Sbjct: 233 SLLQKEMEDFNPIKDVLIRLSEEAITITLDTHVDEEDDFPEGKEKFRLHRYRERNNKLVK 292

Query: 198 WILQQ-----SKGICENCGKN-APFYLNDGNPYLEVHHVIPLSSGGADT---TDNCVALC 248
              ++      +  CE CG +    Y + G  ++E HH  P+S    D     ++   LC
Sbjct: 293 QAKERFIQVHGRLYCEACGMDFEQVYGDRGRNFIEAHHRKPISEMKNDETTKIEDLAMLC 352

Query: 249 PNCHRELHYSK 259
           PNCH  +H   
Sbjct: 353 PNCHSMIHRKP 363


>UniRef50_Q6LSI1 Putative uncharacterized protein MLL7993 n=1 Tax=Photobacterium
           profundum RepID=Q6LSI1_PHOPR
          Length = 207

 Score = 74.0 bits (180), Expect = 6e-12,   Method: Composition-based stats.
 Identities = 31/111 (27%), Positives = 46/111 (41%), Gaps = 16/111 (14%)

Query: 164 KLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQS----KGI--CENCGKNAPF- 216
            + +   S PEG R    VER   +  R   +     ++      G   CE CG +    
Sbjct: 92  NINQSNDSFPEGKR----VERKHYLRERSSALVEKAKKEYALKNNGRLPCEVCGFDFREC 147

Query: 217 YLNDGNPYLEVHHVIPLS-----SGGADTTDNCVALCPNCHRELHYSKNAK 262
           Y   G+ Y+E HH++PLS      G     ++   +C NCHR LH +    
Sbjct: 148 YGFHGDSYIEAHHIVPLSELCSADGTKTRLEDLAMVCSNCHRMLHRAPRVD 198


>UniRef50_B5ERY9 Restriction endonuclease-like protein n=1 Tax=Acidithiobacillus
           ferrooxidans ATCC 53993 RepID=B5ERY9_ACIF5
          Length = 212

 Score = 73.6 bits (179), Expect = 7e-12,   Method: Composition-based stats.
 Identities = 25/110 (22%), Positives = 47/110 (42%), Gaps = 9/110 (8%)

Query: 152 TDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCG 211
           + D   +   ++  +  T    EG+ + V V      Y R+   +   ++     C  CG
Sbjct: 88  SFDPKRVEFSLADEVVDTSDLHEGAVRLVSVN----AYERNAEARRRCVEAHGSSCVVCG 143

Query: 212 KN-APFYLNDGNPYLEVHHVIPLS-SGG---ADTTDNCVALCPNCHRELH 256
            + A  Y +    ++ V H+ P++  GG    D   + + +CPNCH  +H
Sbjct: 144 FSFAQVYGDVAAGFIHVDHLSPIALKGGNYKVDPVSDLLPVCPNCHAVIH 193


>UniRef50_B1KV86 Hnh endonuclease n=5 Tax=Firmicutes RepID=B1KV86_CLOBM
          Length = 233

 Score = 73.2 bits (178), Expect = 8e-12,   Method: Composition-based stats.
 Identities = 28/101 (27%), Positives = 41/101 (40%), Gaps = 12/101 (11%)

Query: 184 RLQKVYVRDPMVKAWILQQSKGI-----CENCGKN-APFYLNDGNPYLEVHHVIPLSS-- 235
           R      R+  V     +  K       CE CG N    Y   G  ++E HH+ P+S   
Sbjct: 133 RQHICIERNAKVIKMAKENFKKKYGVLKCEVCGFNFEKKYGKLGEDFIEGHHIKPVSELK 192

Query: 236 -GGADTTDNCVALCPNCHRELHYSKN---AKELIEMLYVNI 272
            G     ++ V LC NCH+ +H  +     K L  ++  NI
Sbjct: 193 EGEKTKVEDIVLLCSNCHKMIHRKRPWLSKKRLKTLIVQNI 233


>UniRef50_D2AT16 Putative uncharacterized protein n=1 Tax=Streptosporangium roseum
           DSM 43021 RepID=D2AT16_STRRD
          Length = 419

 Score = 72.4 bits (176), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 28/91 (30%), Positives = 38/91 (41%), Gaps = 4/91 (4%)

Query: 190 VRDPMVKAWILQQSKGICENCGKNAPFYLND----GNPYLEVHHVIPLSSGGADTTDNCV 245
            R    K  +L + KG CEN     P   +D    G P L+V H+   + GG D  +  +
Sbjct: 323 ARSTPAKRAVLLRCKGACENPDCENPGRPSDTSVGGGPILDVDHIDDHAKGGRDYPELMI 382

Query: 246 ALCPNCHRELHYSKNAKELIEMLYVNINRLQ 276
           ALCPNCH      ++   L E L        
Sbjct: 383 ALCPNCHAVKTRGRSRDVLRERLREVARERH 413


>UniRef50_D2QLF7 HNH endonuclease n=1 Tax=Spirosoma linguale DSM 74
           RepID=D2QLF7_9SPHI
          Length = 267

 Score = 72.4 bits (176), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 5/74 (6%)

Query: 188 VYVRDPMVKAWILQQSKGICENCGKNAPF-YLNDGNPYLEVHHVIPLSSGGA----DTTD 242
            Y +D   K   L+    +C  C  +  + Y + G  +++VHH++P SS       D   
Sbjct: 171 SYEKDLEAKQLCLEHFGPVCIICNIDFEYAYGSIGKNFIQVHHIVPASSIPKRYIVDPIR 230

Query: 243 NCVALCPNCHRELH 256
           +   +CPNCH  LH
Sbjct: 231 DLRPVCPNCHAMLH 244


>UniRef50_C4XM37 Putative uncharacterized protein n=1 Tax=Desulfovibrio magneticus
           RS-1 RepID=C4XM37_DESMR
          Length = 251

 Score = 72.0 bits (175), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 30/130 (23%), Positives = 54/130 (41%), Gaps = 17/130 (13%)

Query: 143 GELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQ 202
           G    + Q    + +   R  K++ K   Q E S+  +E ++             +++  
Sbjct: 127 GVDRSIGQKNLQKYIAEAREGKVLTKIHVQRERSKSLIESKK------------KYVMNT 174

Query: 203 SKGI-CENCGKNA-PFYLNDGNPYLEVHHVIPLS---SGGADTTDNCVALCPNCHRELHY 257
              + CE CG +   FY   G  + EVHH+ PLS   +  +   ++   +C NCHR +H 
Sbjct: 175 CGVLECEVCGFSFHKFYGERGKNFAEVHHIKPLSYLDAEASTKIEDLAIVCSNCHRMIHS 234

Query: 258 SKNAKELIEM 267
                 + E+
Sbjct: 235 QLPWLAIQEL 244


>UniRef50_Q984I3 Mll7993 protein n=1 Tax=Mesorhizobium loti RepID=Q984I3_RHILO
          Length = 332

 Score = 72.0 bits (175), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 9/97 (9%)

Query: 171 SQPEGSRKPVEVERLQKVYVRDP----MVKAWILQQSKGI-CENCGKN-APFYLNDGNPY 224
           +  EGS +   V R  K   RD       KA +L     + CE C       Y + G  +
Sbjct: 218 TDDEGSAEGSVVLRAHKTRERDATLASKKKAAVLAALGELACEVCDMTFQKHYGDHGKGF 277

Query: 225 LEVHHVIPLS---SGGADTTDNCVALCPNCHRELHYS 258
           +EVHH+ P++    G   T      +C NCH+ LH  
Sbjct: 278 IEVHHIDPIALSEEGRRTTLAQLACVCSNCHKMLHRG 314


>UniRef50_A4G659 Putative restriction endonuclease n=1 Tax=Herminiimonas
           arsenicoxydans RepID=A4G659_HERAR
          Length = 269

 Score = 72.0 bits (175), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 37/167 (22%), Positives = 63/167 (37%), Gaps = 14/167 (8%)

Query: 99  KMCGYQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLL 158
           K   YQ  F +  +  I   ++   +LIN P      F  +    +     + +   S +
Sbjct: 83  KKTAYQYSF-KASKGVISYKDKANAVLINQPQYLYPVFLFT--ECKDGWEFEGSFSVSEI 139

Query: 159 NMRVSKLIKKTLSQPEGSRKPVEVERLQKVY------VRDPMVKAWILQQSKGICENCGK 212
             +   L +             E +  ++ Y       R   V + + + +   C+ C K
Sbjct: 140 EEKYLVLKRGENISNAVDFDESEYQEGERKYVTHLLAERSRSVVSMLKELNDWKCDVCQK 199

Query: 213 NAPFYLNDGNPYLEVHHVIPLSSGGADTT---DNCVALCPNCHRELH 256
           N  F    G  Y+E HH IP+SS  +       +   LCPNCH+ +H
Sbjct: 200 N--FEKEYGVKYIEAHHKIPISSFSSKHPVKSSDFALLCPNCHKAIH 244


>UniRef50_Q82CY5 Putative uncharacterized protein n=1 Tax=Streptomyces avermitilis
           RepID=Q82CY5_STRAW
          Length = 177

 Score = 72.0 bits (175), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 27/83 (32%), Positives = 32/83 (38%), Gaps = 4/83 (4%)

Query: 179 PVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSG-- 236
           P       +  VRD  V   +     G C+ CG        DG PY E  H+ PL     
Sbjct: 44  PKTRAARIQRLVRDAAVSRNVKDLYGGECQACGLR--LVGPDGRPYSEGAHIRPLGKPHC 101

Query: 237 GADTTDNCVALCPNCHRELHYSK 259
           G D   N + LCPNCH  L    
Sbjct: 102 GPDVEPNVLCLCPNCHVRLDIGA 124


>UniRef50_B4D4V1 HNH endonuclease n=1 Tax=Chthoniobacter flavus Ellin428
           RepID=B4D4V1_9BACT
          Length = 212

 Score = 71.7 bits (174), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 33/118 (27%), Positives = 50/118 (42%), Gaps = 10/118 (8%)

Query: 160 MRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLN 219
           +R        +SQP    +P  V +     +RD  + + +      IC+ CG        
Sbjct: 80  VRCDARAANDISQP---SQPDRVLQRISRIIRDTAISSELKLLYDHICQLCGTQLVVCDR 136

Query: 220 DGNPYLEVHHVIPLSS--GGADTTDNCVALCPNCHRELHYSKNA--KELIEMLYVNIN 273
               Y E HH+ PL     G+DT DN + +CPNCH  L Y+      E ++ L   I+
Sbjct: 137 L---YSEAHHIRPLGRPHDGSDTRDNLLCVCPNCHVLLDYAAIPIQPEALKHLKHRIS 191


>UniRef50_C8S4R5 HNH endonuclease n=1 Tax=Rhodobacter sp. SW2 RepID=C8S4R5_9RHOB
          Length = 343

 Score = 71.7 bits (174), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 25/95 (26%), Positives = 40/95 (42%), Gaps = 9/95 (9%)

Query: 182 VERLQKVYVRDPMVKA-----WILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSS 235
           V RL +   R+ ++       +  +Q +  CE C  +    Y   G  ++E HH  P+SS
Sbjct: 243 VTRLHRFRERNRLLVKRKKESYAKKQGRLCCEACDFDFGAKYGQRGEGFIECHHTKPVSS 302

Query: 236 ---GGADTTDNCVALCPNCHRELHYSKNAKELIEM 267
              G      + V LC NCHR +H       +  +
Sbjct: 303 LTIGEKTKVSDLVLLCANCHRMVHAKAPWLTVAAL 337


>UniRef50_C7NQZ2 HNH endonuclease n=1 Tax=Halorhabdus utahensis DSM 12940
           RepID=C7NQZ2_HALUD
          Length = 407

 Score = 70.9 bits (172), Expect = 4e-11,   Method: Composition-based stats.
 Identities = 28/121 (23%), Positives = 44/121 (36%), Gaps = 4/121 (3%)

Query: 140 IIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWI 199
           I    L++  +   D   +    +     +    +    P  VE      VR+  +   +
Sbjct: 240 IFDSILTDEDEQVSDSQAILDAANSSNIDSEEFVDDVITPDSVETTISRTVRNTTLVKEL 299

Query: 200 LQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSS--GGADTTDNCVALCPNCHRELHY 257
                  C+ C  ++P Y      Y E HH+ PL     G DT  N + LCPN H +  Y
Sbjct: 300 KGAYDYECQVC--DSPRYQGPDKRYAEGHHIKPLGEPHNGPDTPSNILVLCPNHHADFDY 357

Query: 258 S 258
            
Sbjct: 358 G 358


>UniRef50_Q3IBU7 Putative HNH endonuclease n=1 Tax=Pseudoalteromonas haloplanktis
           TAC125 RepID=Q3IBU7_PSEHT
          Length = 420

 Score = 70.9 bits (172), Expect = 4e-11,   Method: Composition-based stats.
 Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 6/72 (8%)

Query: 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254
           VKA++LQ+    C++ G+            L VHH +  S GG D   N +ALC  CH +
Sbjct: 184 VKAYVLQRDNYKCQS-GRKTKHNAK-----LHVHHKVFRSQGGTDALSNLIALCETCHND 237

Query: 255 LHYSKNAKELIE 266
           LH  K   ++  
Sbjct: 238 LHVGKFELKVKR 249


>UniRef50_C4F8E8 Putative uncharacterized protein n=1 Tax=Collinsella intestinalis
           DSM 13280 RepID=C4F8E8_9ACTN
          Length = 154

 Score = 70.9 bits (172), Expect = 5e-11,   Method: Composition-based stats.
 Identities = 24/82 (29%), Positives = 38/82 (46%), Gaps = 10/82 (12%)

Query: 174 EGSRKPVEVERLQKVYVRDP---MVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHV 230
           +G +KP+   R      R P    ++  +L++    C+ CG  AP         L V H+
Sbjct: 62  DGKKKPMRARRSSGA-ERKPLPPRIRYEVLERDGYTCQYCGAKAPSVT------LHVDHI 114

Query: 231 IPLSSGGADTTDNCVALCPNCH 252
           +P++ GG D   N VA C  C+
Sbjct: 115 VPVAEGGTDDLSNLVAACEYCN 136


>UniRef50_B8FFI4 HNH endonuclease n=1 Tax=Desulfatibacillum alkenivorans AK-01
           RepID=B8FFI4_DESAA
          Length = 299

 Score = 70.9 bits (172), Expect = 5e-11,   Method: Composition-based stats.
 Identities = 30/126 (23%), Positives = 47/126 (37%), Gaps = 20/126 (15%)

Query: 140 IIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWI 199
           I  G + EL     ++S+       +      +  G  K                 K  +
Sbjct: 173 INEGTIEELPDIDLNKSVKEGNPRLIAHLKRERNSGIVKTK---------------KEEV 217

Query: 200 LQQSKG-ICENCGKN-APFYLNDGNPYLEVHHVIPLSS-GGA--DTTDNCVALCPNCHRE 254
           L++     CE CG + +  Y   G  + EVHH+ PLS   G      ++   +C NCHR 
Sbjct: 218 LKRKGCLKCEVCGFDFSSVYGEHGYGFCEVHHLQPLSKADGVVQTKLEDLSIVCSNCHRI 277

Query: 255 LHYSKN 260
           +H S  
Sbjct: 278 IHRSNP 283


>UniRef50_B0TQV8 Restriction endonuclease-like protein n=1 Tax=Shewanella
           halifaxensis HAW-EB4 RepID=B0TQV8_SHEHH
          Length = 289

 Score = 70.5 bits (171), Expect = 6e-11,   Method: Composition-based stats.
 Identities = 36/145 (24%), Positives = 58/145 (40%), Gaps = 10/145 (6%)

Query: 132 YSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVR 191
           Y  SF  ++ R         T+   + N+   K +        G  +   + R+ K   R
Sbjct: 127 YHSSFVEAV-RYSACTQGSITEVNDIKNLTQLKGVSSENVGDYGVDEGKPIYRVHKTRER 185

Query: 192 DPMV----KAWILQQSKGIC-ENCGKNA-PFYLNDGNPYLEVHHVIPLS---SGGADTTD 242
           DP +    K  +L  +  +C E C  +    Y + G  + E HH+ PL+   S      D
Sbjct: 186 DPKLTKDKKQQVLSITGKLCCEICNFDFYECYGDLGLGFAECHHLEPLALRESNKKTKLD 245

Query: 243 NCVALCPNCHRELHYSKNAKELIEM 267
           +   LC NCHR +HY      + E+
Sbjct: 246 DLAILCANCHRMIHYPTQWLSVEEL 270


>UniRef50_C3XKK9 Restriction endonuclease n=1 Tax=Helicobacter winghamensis ATCC
           BAA-430 RepID=C3XKK9_9HELI
          Length = 400

 Score = 70.5 bits (171), Expect = 6e-11,   Method: Composition-based stats.
 Identities = 34/154 (22%), Positives = 55/154 (35%), Gaps = 20/154 (12%)

Query: 130 GIY-----SDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVER 184
           GIY       SF  +     ++       D+ L    + K+ K    + E  ++      
Sbjct: 224 GIYYFSCEEPSFTQNSFEERIAHYLHIIYDKHLSPYEIEKIRKDLAFEKENDKE------ 277

Query: 185 LQKVYVRDPMVKAWILQQSKGICENCG-----KNAPFYLNDGNPYLEVHHVIPLSSGG-A 238
               + RD  +       S  IC  C      ++  F    G  Y E+HH I +      
Sbjct: 278 ---SFSRDGQIVKIFKYSSDDICAACNDYYDIQDRSFLTKMGRYYTEIHHCISVGKDKQL 334

Query: 239 DTTDNCVALCPNCHRELHYSKNAKELIEMLYVNI 272
           D  +N   LCP CHR L    +++   + +  NI
Sbjct: 335 DVLENLTKLCPVCHRALKKGASSESYQKQIINNI 368


>UniRef50_Q8DK67 Reverse transcriptase n=1 Tax=Thermosynechococcus elongatus BP-1
           RepID=Q8DK67_THEEB
          Length = 317

 Score = 70.1 bits (170), Expect = 7e-11,   Method: Composition-based stats.
 Identities = 21/86 (24%), Positives = 37/86 (43%), Gaps = 15/86 (17%)

Query: 171 SQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHV 230
            + +    P +  R           +  + ++  GIC  CG        + +   E+HH+
Sbjct: 232 QRKKLKEAPAQYRRT----------RRELWKKQGGICPVCGGEI-----EQDMLTEIHHI 276

Query: 231 IPLSSGGADTTDNCVALCPNCHRELH 256
           +P   GG D  DN V +  NCH+++H
Sbjct: 277 LPKHKGGTDDLDNLVLIHTNCHKQVH 302


>UniRef50_D0C4R2 HNH endonuclease n=1 Tax=Acinetobacter sp. RUH2624
           RepID=D0C4R2_9GAMM
          Length = 298

 Score = 69.7 bits (169), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 38/148 (25%), Positives = 57/148 (38%), Gaps = 15/148 (10%)

Query: 130 GIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKL-IKKTLSQPEGSRKPVEVERLQKV 188
           GI   + W + +  E   L +           V+ L     L   EGS K     R   V
Sbjct: 148 GIGQSNVWYAKLE-ETKPLVEKVKKYIEKYCLVNDLPDIDDLGVTEGSLK----IRRHLV 202

Query: 189 YVRDPMVKAWILQQ-----SKGICENCGKN-APFYLNDGNPYLEVHHVIPLSSGGA---D 239
             R+  +     Q+      K  CE C  +    Y   G  + EVHH+IPL+   +    
Sbjct: 203 RERNLSIIKQKKQKILSDFGKLECEVCHFDFEKNYGEIGKEFCEVHHLIPLNQSDSIVKT 262

Query: 240 TTDNCVALCPNCHRELHYSKNAKELIEM 267
             ++   +C NCHR LH  +   E+ E+
Sbjct: 263 KLEDLAIVCSNCHRMLHKGQPLLEIHEL 290


>UniRef50_D0WS63 Putative uncharacterized protein n=1 Tax=Vibrio alginolyticus 40B
           RepID=D0WS63_VIBAL
          Length = 203

 Score = 69.3 bits (168), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 21/80 (26%), Positives = 33/80 (41%), Gaps = 5/80 (6%)

Query: 190 VRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDN--CVAL 247
            R+  +      + K  C+ C         +G   ++ HH  PL++ G   T+    V L
Sbjct: 121 ARNQKLATEAKIRDKHTCQVCRYKMQI---NGKYVIDCHHTNPLATTGKTNTELSTLVCL 177

Query: 248 CPNCHRELHYSKNAKELIEM 267
           CPNCHR  H       + E+
Sbjct: 178 CPNCHRIAHLKSPPYTVAEL 197


>UniRef50_Q4K9Y7 Putative uncharacterized protein n=1 Tax=Pseudomonas fluorescens
           Pf-5 RepID=Q4K9Y7_PSEF5
          Length = 282

 Score = 69.3 bits (168), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 41/185 (22%), Positives = 69/185 (37%), Gaps = 26/185 (14%)

Query: 107 FSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLI 166
           ++  GR  +  GN+ ++++           W                  + + M  +  I
Sbjct: 108 YTNNGRTGLAKGNKDEQLV-----------WLEFANDPERLAEVVAAINANVQMIPASPI 156

Query: 167 KKTLSQPEGSRKPVE---VERLQKVYVRDPMV----KAWILQQSKG-ICENCGKN-APFY 217
             + +   G  +  E   + R+ +V  RD  +    K   L Q     CE CG N +  Y
Sbjct: 157 DLSAADDPGFFEAEEGKVLTRVHRVRERDKKIVKRKKEEALTQHGALQCEACGFNFSQTY 216

Query: 218 LNDGNPYLEVHHVIPLSS---GGADTTDNCVALCPNCHRELHYSKNA---KELIEMLYVN 271
             D    ++VHH  PL +   G      +   LC NCHR LH  +      E+ E    N
Sbjct: 217 GADVEGVIDVHHTKPLHTLQPGDKTKLADLALLCANCHRVLHSQRKWLSVAEVKERYQAN 276

Query: 272 INRLQ 276
           + ++Q
Sbjct: 277 LKQIQ 281


>UniRef50_A1B3Q8 HNH endonuclease n=2 Tax=Rhodobacteraceae RepID=A1B3Q8_PARDP
          Length = 109

 Score = 69.0 bits (167), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 24/84 (28%), Positives = 37/84 (44%), Gaps = 9/84 (10%)

Query: 182 VERLQKVYVRD----PMVKAWILQQSKGI-CENCGKNA-PFYLNDGNPYLEVHHVIPLS- 234
           + R+     R+       KA  L+Q   + CE CG +    Y   G  ++E HH +P+S 
Sbjct: 1   MTRVHVSRERNSTLVKKKKAVALRQHGCLACEVCGFDFLQTYGERGREFIECHHTLPISS 60

Query: 235 --SGGADTTDNCVALCPNCHRELH 256
               G     +   +C NCHR +H
Sbjct: 61  LGEHGKTNLKDLALVCSNCHRMIH 84


>UniRef50_C7D6X3 Putative uncharacterized protein n=1 Tax=Thalassiobium sp. R2A62
           RepID=C7D6X3_9RHOB
          Length = 192

 Score = 69.0 bits (167), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 11/99 (11%)

Query: 185 LQKVYVRDPMVKAWILQQSKGICENC----GKNAPFYLNDGNPYLEVHH---VIPLSSGG 237
           L +   R P ++  +L++   IC+ C     K+  F     +  L++HH   +  L+ G 
Sbjct: 92  LSRRIERAPSIRKEVLEKLPPICQACRLDPAKHYSFRGKIDHYPLDIHHSKPIQSLAEGE 151

Query: 238 AD---TTDNCVALCPNCHRELHYSKNAKELIEMLYVNIN 273
           +      D+ + LCP CHR +H   +  +L E L   I 
Sbjct: 152 SRRYRVPDDFMVLCPTCHRMIHKQSDPSDL-EALKSIIR 189


>UniRef50_C4ZAA3 Putative uncharacterized protein n=1 Tax=Eubacterium rectale ATCC
           33656 RepID=C4ZAA3_EUBR3
          Length = 251

 Score = 69.0 bits (167), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 35/164 (21%), Positives = 68/164 (41%), Gaps = 15/164 (9%)

Query: 118 GNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLI--KKTLSQPEG 175
           G R ++    V  +Y    W  +   E++E+ +   D ++   +V  L   ++T+S+ + 
Sbjct: 70  GQRNRKPTETVKELYGQ--WNVMEFEEITEIVKSVLDGTMEESQVINLEVDEETVSEYDV 127

Query: 176 SR-------KPVEVERLQKVYVRDPMVKA-WILQQ-SKGICENCGKNAPFYLNDGNPYLE 226
                         + ++ V  R    K   +L++     C+ CG+N       G    E
Sbjct: 128 ETYLNFDDNTAALNKTVKSVMERTYSKKKVEMLKRLYAYRCQICGQN--VGEEHGVNIAE 185

Query: 227 VHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYV 270
            HH+   S    +++DN + LCPN H  +H      +  E+ Y+
Sbjct: 186 AHHIKYFSKSVDNSSDNLLILCPNHHSLIHVLNPKFDYDELQYI 229


>UniRef50_B4SCA5 HNH nuclease n=1 Tax=Pelodictyon phaeoclathratiforme BU-1
           RepID=B4SCA5_PELPB
          Length = 340

 Score = 69.0 bits (167), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 31/119 (26%), Positives = 44/119 (36%), Gaps = 8/119 (6%)

Query: 142 RGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQ 201
             E  EL+Q      +    + +L     S  E      E+   +K Y RD    A I  
Sbjct: 203 EKEQEELAQFYKQAKIKEEILDELNNLQPSDSE------EIIVNKKTYKRDNKTIAQIKI 256

Query: 202 QSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKN 260
                C+ CG        D + Y+E  H+      G +T DN + LCPN H+E      
Sbjct: 257 LRDFKCQICGV--TITKKDRSKYIEAAHIKAKHQKGRETIDNIILLCPNHHKEFDLGDR 313


>UniRef50_Q2FRM5 HNH endonuclease n=1 Tax=Methanospirillum hungatei JF-1
           RepID=Q2FRM5_METHJ
          Length = 334

 Score = 68.6 bits (166), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 21/94 (22%), Positives = 37/94 (39%), Gaps = 11/94 (11%)

Query: 166 IKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYL 225
           I   + + E    P++ +       R+  +   +       C+ C         +    +
Sbjct: 221 IHSLIQEEERRILPMQTK-------RNRYLAYLVKNLHGNCCQICSA----MGEETTGPV 269

Query: 226 EVHHVIPLSSGGADTTDNCVALCPNCHRELHYSK 259
           EVHH+IPLS  G D  +N + LC   H+ +H   
Sbjct: 270 EVHHIIPLSRQGKDLAENMLTLCAPHHQAVHAGS 303


>UniRef50_A0ZAT3 Putative uncharacterized protein n=1 Tax=Nodularia spumigena
           CCY9414 RepID=A0ZAT3_NODSP
          Length = 394

 Score = 68.6 bits (166), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 29/99 (29%), Positives = 46/99 (46%), Gaps = 10/99 (10%)

Query: 164 KLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQ-SKGICENCGKNAPFYLNDGN 222
           + I + +   EG R  V   R      R P ++     + +  +C+ C  N        +
Sbjct: 266 REIPEDIIFTEGRRVRVTHLRT----ERSPQLRRLFFSRNALPVCDMCSCNTRHRYPWTD 321

Query: 223 PYLEVHHVIPLSS-----GGADTTDNCVALCPNCHRELH 256
             LE+HH++PLSS     G   + ++ V LCPNCHR +H
Sbjct: 322 NLLEIHHLLPLSSAITVTGEGTSLEDVVGLCPNCHRSVH 360


>UniRef50_B9JB56 Putative uncharacterized protein n=1 Tax=Agrobacterium radiobacter
           K84 RepID=B9JB56_AGRRK
          Length = 219

 Score = 67.8 bits (164), Expect = 4e-10,   Method: Composition-based stats.
 Identities = 24/75 (32%), Positives = 32/75 (42%), Gaps = 4/75 (5%)

Query: 183 ERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLS--SGGADT 240
           E      +RD ++   +       C+ CG      L DG  Y E HH+IPL     G D 
Sbjct: 107 EVTTNRIIRDTVMTCKVKALHHSKCQICG--TSISLPDGRAYSEAHHIIPLGAPHRGPDI 164

Query: 241 TDNCVALCPNCHREL 255
             N + +CPN H  L
Sbjct: 165 PSNIIIVCPNHHAML 179


>UniRef50_A5ELB4 Putative uncharacterized protein n=1 Tax=Bradyrhizobium sp. BTAi1
           RepID=A5ELB4_BRASB
          Length = 283

 Score = 67.4 bits (163), Expect = 4e-10,   Method: Composition-based stats.
 Identities = 32/160 (20%), Positives = 61/160 (38%), Gaps = 8/160 (5%)

Query: 116 PSGNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEG 175
           P  + TK   +N   +  D+ WA       +         + L +++S    +       
Sbjct: 124 PQSDGTKPSKVNARRL-DDTAWAITEYDLATGRCVMVRGTAPLPVKISAEDLELSGFEGT 182

Query: 176 SRKPVEVERLQKVYVRDPMVKAWILQQSKGICEN--CGKN-APFYLNDGNPYLEVHHVIP 232
            R    + R ++  +R   +   + +  K +CE   CG +    Y + G  Y +VHH+ P
Sbjct: 183 ERSRFVIHRRREGAMRRAKISEALSKTGKLVCEVPKCGFDFEARYGSLGKGYAQVHHLTP 242

Query: 233 LSSGGAD----TTDNCVALCPNCHRELHYSKNAKELIEML 268
           L     +       +   +C NCH  +H     +EL  ++
Sbjct: 243 LHKAPPEGRKIKLSDLAIVCANCHAMIHAGGECRELARLI 282


>UniRef50_A6TVA6 HNH endonuclease n=6 Tax=Bacteria RepID=A6TVA6_ALKMQ
          Length = 124

 Score = 67.4 bits (163), Expect = 4e-10,   Method: Composition-based stats.
 Identities = 32/105 (30%), Positives = 49/105 (46%), Gaps = 15/105 (14%)

Query: 153 DDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVR--DPMVKAWILQQSKGICENC 210
            D         K++ K  +Q +  R P   +R  + + R  D  +KA  L      CE C
Sbjct: 18  SDSGEYCAEHKKVVTKRYNQYQ--RDPASNKRYGRSWKRIRDRYIKAHPL------CEEC 69

Query: 211 GKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHREL 255
            +N      +     EVHH++PLS GG + T N +ALC +CH ++
Sbjct: 70  DRNGRIKAAE-----EVHHILPLSKGGGNETSNLMALCKSCHSKI 109


>UniRef50_UPI000197A09F restriction endonuclease n=1 Tax=Helicobacter canadensis MIT
           98-5491 RepID=UPI000197A09F
          Length = 363

 Score = 67.0 bits (162), Expect = 6e-10,   Method: Composition-based stats.
 Identities = 42/198 (21%), Positives = 78/198 (39%), Gaps = 23/198 (11%)

Query: 90  GNSPRDIRLKMCGYQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSELS 149
           G + R+ +L++  Y  Y  + G   I      KR    +   Y+ + + S       E  
Sbjct: 142 GENRRNTQLRINLYW-YLEKIGLMNIYKAEIVKRAY-GIDYEYTGNGYYSF------ECR 193

Query: 150 QPTDDESLLNMRVS----KLIKKTLSQPEGSRKPVEV---ERLQKVYVRDPMVKAWILQQ 202
            PT +++    R++    +++   L++ +      E+   E     + R+  +   +  Q
Sbjct: 194 APTFNKNSFQERINFYATRILNNDLTERDIKNLREELNFDENTNNDFKRNINIAQLVRYQ 253

Query: 203 SKGICENCGK-----NAPFYLND--GNPYLEVHHVIPLSSGGA-DTTDNCVALCPNCHRE 254
           +K  C  C       +  F L       Y E+HH + +      D  +N   LCP CHR 
Sbjct: 254 TKDECAACKNKYNIADRSFLLRKFPERYYTEIHHFVSVGKEKELDVVENLTKLCPACHRA 313

Query: 255 LHYSKNAKELIEMLYVNI 272
           L   K +++  + L  NI
Sbjct: 314 LGRGKASEQYQKKLIENI 331


>UniRef50_C5ZWY1 Putative uncharacterized protein n=1 Tax=Helicobacter canadensis
           MIT 98-5491 RepID=C5ZWY1_9HELI
          Length = 410

 Score = 67.0 bits (162), Expect = 6e-10,   Method: Composition-based stats.
 Identities = 42/198 (21%), Positives = 78/198 (39%), Gaps = 23/198 (11%)

Query: 90  GNSPRDIRLKMCGYQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSELS 149
           G + R+ +L++  Y  Y  + G   I      KR    +   Y+ + + S       E  
Sbjct: 189 GENRRNTQLRINLYW-YLEKIGLMNIYKAEIVKRAY-GIDYEYTGNGYYSF------ECR 240

Query: 150 QPTDDESLLNMRVS----KLIKKTLSQPEGSRKPVEV---ERLQKVYVRDPMVKAWILQQ 202
            PT +++    R++    +++   L++ +      E+   E     + R+  +   +  Q
Sbjct: 241 APTFNKNSFQERINFYATRILNNDLTERDIKNLREELNFDENTNNDFKRNINIAQLVRYQ 300

Query: 203 SKGICENCGK-----NAPFYLND--GNPYLEVHHVIPLSSGGA-DTTDNCVALCPNCHRE 254
           +K  C  C       +  F L       Y E+HH + +      D  +N   LCP CHR 
Sbjct: 301 TKDECAACKNKYNIADRSFLLRKFPERYYTEIHHFVSVGKEKELDVVENLTKLCPACHRA 360

Query: 255 LHYSKNAKELIEMLYVNI 272
           L   K +++  + L  NI
Sbjct: 361 LGRGKASEQYQKKLIENI 378


>UniRef50_C9RBS6 HNH endonuclease n=4 Tax=Ammonifex degensii KC4 RepID=C9RBS6_AMMDK
          Length = 388

 Score = 67.0 bits (162), Expect = 7e-10,   Method: Composition-based stats.
 Identities = 23/63 (36%), Positives = 31/63 (49%), Gaps = 10/63 (15%)

Query: 196 KAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHREL 255
           +  +L +  G C  CG             L+ HH++P S GG DT +N V LC  CHR+L
Sbjct: 177 REKVLNR-DGACVLCGSTRR---------LQRHHLVPRSKGGTDTPENQVLLCAECHRKL 226

Query: 256 HYS 258
           H  
Sbjct: 227 HAG 229


>UniRef50_C3AFV2 Putative uncharacterized protein n=1 Tax=Bacillus mycoides DSM 2048
           RepID=C3AFV2_BACMY
          Length = 140

 Score = 67.0 bits (162), Expect = 7e-10,   Method: Composition-based stats.
 Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 10/78 (12%)

Query: 180 VEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGAD 239
            E E+L++ + R+   + W   +   +CE C                +HH IPL +GG +
Sbjct: 2   EEYEQLRQKF-RNISKQYWKQTKKPKMCEKCFSKTDV---------HLHHKIPLKTGGTN 51

Query: 240 TTDNCVALCPNCHRELHY 257
             DN + LC  CH E H 
Sbjct: 52  DYDNLIPLCEECHWEFHR 69


>UniRef50_UPI0000E87DB3 hypothetical protein MB2181_05395 n=1 Tax=Methylophilales bacterium
           HTCC2181 RepID=UPI0000E87DB3
          Length = 301

 Score = 66.7 bits (161), Expect = 8e-10,   Method: Composition-based stats.
 Identities = 29/141 (20%), Positives = 46/141 (32%), Gaps = 16/141 (11%)

Query: 127 NVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQ----------PEGS 176
           +VP  Y      ++      E  Q         +     IK  + +           EG+
Sbjct: 119 SVPAFYRYDGLFNVEN-YWIEKGQEKFKVYRFRLIEINAIKINIEKNTPKKTSQVTAEGN 177

Query: 177 RKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSS- 235
             P          +RD  +   + +  +  C+ C  N    +  G  Y E  H+ PL   
Sbjct: 178 ESPGRKTVTTSTPIRDQKLAKQVKELYEYKCQIC--NIQINVPTGF-YAESAHIKPLGKP 234

Query: 236 -GGADTTDNCVALCPNCHREL 255
             G D  +N + LCPN H   
Sbjct: 235 HHGPDKVENIICLCPNHHVMF 255


>UniRef50_B4SDY4 HNH nuclease n=4 Tax=Bacteria RepID=B4SDY4_PELPB
          Length = 309

 Score = 66.7 bits (161), Expect = 8e-10,   Method: Composition-based stats.
 Identities = 19/63 (30%), Positives = 31/63 (49%)

Query: 194 MVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHR 253
            ++  +LQ+    C+ CG +   +      +LE HH+     GG +T +N V LC  CH 
Sbjct: 245 AIRREVLQRDDYRCQQCGWHQEMWNQSDPRHLEAHHIKQHVEGGENTKENLVTLCNICHD 304

Query: 254 ELH 256
           + H
Sbjct: 305 KEH 307


>UniRef50_B2A7T7 HNH endonuclease n=1 Tax=Natranaerobius thermophilus JW/NM-WN-LF
           RepID=B2A7T7_NATTJ
          Length = 232

 Score = 66.3 bits (160), Expect = 1e-09,   Method: Composition-based stats.
 Identities = 19/71 (26%), Positives = 31/71 (43%), Gaps = 4/71 (5%)

Query: 208 ENCGKNAPFYLNDGNPYLEVHHVIPLSSGG----ADTTDNCVALCPNCHRELHYSKNAKE 263
           EN       Y   G  ++ +HH++P+ + G     D   +   +CPNCH  LH      +
Sbjct: 19  ENNTIPEEKYGEIGEGFIHIHHIVPIKNKGGNYTLDPVRDLRPVCPNCHAMLHREDPPLK 78

Query: 264 LIEMLYVNINR 274
           + E+     NR
Sbjct: 79  IDELKKQLENR 89


>UniRef50_Q2FQI6 HNH endonuclease n=1 Tax=Methanospirillum hungatei JF-1
           RepID=Q2FQI6_METHJ
          Length = 163

 Score = 66.3 bits (160), Expect = 1e-09,   Method: Composition-based stats.
 Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 9/62 (14%)

Query: 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254
           ++  IL++    C+ CG+            L VHH+IPLS GG  T  N   LC +CH++
Sbjct: 62  IRRQILERDGYRCQICGEQRD---------LSVHHIIPLSEGGDSTASNLRVLCHSCHQQ 112

Query: 255 LH 256
            H
Sbjct: 113 AH 114


>UniRef50_C6WXV3 HNH endonuclease n=3 Tax=Proteobacteria RepID=C6WXV3_METML
          Length = 238

 Score = 65.9 bits (159), Expect = 1e-09,   Method: Composition-based stats.
 Identities = 27/112 (24%), Positives = 42/112 (37%), Gaps = 11/112 (9%)

Query: 154 DESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQ----SKGICEN 209
              +     S+ +++ +   EG        R      R+P ++  +L          CE 
Sbjct: 112 RAGVTAFEASEPVQEDVVFAEGRVITELHTRR----EREPKLRGQLLSSRRVSGNLFCEM 167

Query: 210 CGKNAPFYLN-DGNPYLEVHHVIPLSSGG--ADTTDNCVALCPNCHRELHYS 258
           CG             + E HH+IPLS+ G       +   LC NCHR LH +
Sbjct: 168 CGAPPHTSNAMLQEAHFEAHHIIPLSNTGVRKTRLSDLALLCANCHRLLHRA 219


>UniRef50_B7JSJ9 DNA helicase, putative n=1 Tax=Bacillus cereus AH820
           RepID=B7JSJ9_BACC0
          Length = 278

 Score = 65.9 bits (159), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 27/127 (21%), Positives = 45/127 (35%), Gaps = 6/127 (4%)

Query: 134 DSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDP 193
           DSF   ++        +  +DE     R   L +               ++ ++      
Sbjct: 127 DSF---VLNDYYIYDEEIVEDELGEKKRDIILEEAKNFIDYKEHYVKIDDKAKRRKESSA 183

Query: 194 MVKAWILQQSKGICENCGKNAPFYLNDGNP--YLEVHHVIPLSSGGADTTDNCVALCPNC 251
             K   + +    C+ CG    +   +      +EV H+I  S GG +T DN   LCPNC
Sbjct: 184 QKKRIAILE-DHTCQVCGFKEEYIKANNKKGWIIEVDHIIEKSKGGGETFDNLWVLCPNC 242

Query: 252 HRELHYS 258
           H +    
Sbjct: 243 HAKKTRG 249


>UniRef50_A4W6M3 HNH endonuclease n=7 Tax=Enterobacteriaceae RepID=A4W6M3_ENT38
          Length = 282

 Score = 65.5 bits (158), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 5/70 (7%)

Query: 190 VRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGAD---TTDNCVA 246
            R+  V   +  ++  +C+ C  N  F  +    Y+E HH  PL +       TT++   
Sbjct: 191 ERNAQVIKELKNKAPWVCDVC--NLEFINSYSKNYIEAHHKKPLHTYKNSHTVTTNDFAL 248

Query: 247 LCPNCHRELH 256
           LCPNCH+ +H
Sbjct: 249 LCPNCHKAVH 258


>UniRef50_D2RK49 HNH endonuclease n=11 Tax=Bacteria RepID=D2RK49_ACIFE
          Length = 128

 Score = 65.5 bits (158), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 15/99 (15%)

Query: 160 MRVSKLIKKTLSQPEGSRKPVEVERLQKVYV--RDPMVKAWILQQSKGICENCGKNAPFY 217
            +  K+I K   + E  R P   +R  K +   RD  V +  L      CE C KN  + 
Sbjct: 24  EKHQKIIAKRYEKYE--RSPATKKRYGKSWKKIRDAYVSSHPL------CELCLKNGRYV 75

Query: 218 LNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELH 256
           + +     EVHH  PL+ GG    +N +ALC  CH  +H
Sbjct: 76  VAE-----EVHHKKPLAEGGTHAWNNLIALCKACHARIH 109


>UniRef50_Q538B5 MnlI restriction endonuclease n=2 Tax=Moraxella nonliquefaciens
           RepID=Q538B5_MORNO
          Length = 386

 Score = 65.5 bits (158), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 7/89 (7%)

Query: 191 RDPMVKAWILQQSKGICENCG-----KNAPF-YLNDGNPYLEVHHVIPL-SSGGADTTDN 243
           R+  +  ++       C  C      K+  F Y +    YLEVHHVI   S    D  DN
Sbjct: 269 RNQGIVQYVRAYFPDECACCKNQYNIKDRSFTYRHSDRYYLEVHHVISFASDRTLDQIDN 328

Query: 244 CVALCPNCHRELHYSKNAKELIEMLYVNI 272
            V +CP CHR L  ++  ++  + L   I
Sbjct: 329 LVKVCPTCHRALSKNRADEQYQKELISEI 357


>UniRef50_A3X5U3 Putative uncharacterized protein n=2 Tax=Alphaproteobacteria
           RepID=A3X5U3_9RHOB
          Length = 275

 Score = 65.1 bits (157), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 5/63 (7%)

Query: 199 ILQQSKGICENCG-KNAPFYLNDGNPYLEVHHVIPLSSGGA----DTTDNCVALCPNCHR 253
            ++     C  CG +    Y +D    +EVHH+ PL++  A    D   + + LCP+CHR
Sbjct: 192 CIRLHGETCAACGLEPRRRYGDDAGGIIEVHHLEPLANIAAPKPYDPATDLLPLCPSCHR 251

Query: 254 ELH 256
             H
Sbjct: 252 AAH 254


>UniRef50_C3BJL8 Paclitaxel/taxanoid biosynthesis susceptibility protein TS1 n=1
           Tax=Bacillus pseudomycoides DSM 12442 RepID=C3BJL8_9BACI
          Length = 374

 Score = 64.7 bits (156), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 25/87 (28%), Positives = 38/87 (43%), Gaps = 14/87 (16%)

Query: 196 KAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHREL 255
           + ++  +    C+ C K            L  HH+I   SGG+D  DN V +   CH++ 
Sbjct: 142 RYYVFTRDHYTCQICKKKG--------GILHTHHIIERCSGGSDMADNLVTVHEECHQKF 193

Query: 256 HYS------KNAKELIEMLYVNINRLQ 276
           H        K  K+  E  ++NI RLQ
Sbjct: 194 HQGTIKHIFKKPKQYKETAFMNILRLQ 220


>UniRef50_A3YQ82 MnlI restriction endonuclease n=1 Tax=Campylobacter jejuni subsp.
           jejuni 260.94 RepID=A3YQ82_CAMJE
          Length = 259

 Score = 64.7 bits (156), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 26/72 (36%), Positives = 35/72 (48%), Gaps = 6/72 (8%)

Query: 207 CENCGK-----NAPFYLNDGNPYLEVHHVIPLS-SGGADTTDNCVALCPNCHRELHYSKN 260
           C  C K     +  F + +G  YLE+HH I  + S   D  DN V LCP CHR L  ++ 
Sbjct: 156 CAACNKTYNIDDRSFKMKNGFYYLELHHNIAFAYSNECDELDNLVKLCPTCHRALTRNRA 215

Query: 261 AKELIEMLYVNI 272
            +   + L  NI
Sbjct: 216 DENYQKELIKNI 227


>UniRef50_A6FN65 HIT family protein n=5 Tax=root RepID=A6FN65_9RHOB
          Length = 332

 Score = 64.3 bits (155), Expect = 4e-09,   Method: Composition-based stats.
 Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 6/59 (10%)

Query: 194 MVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252
            V+  +L+++K  CE CG +           L V H+IP + GG+D   N  +LC  C+
Sbjct: 135 SVRYEVLKRAKYRCELCGAHED------QAALHVDHIIPRARGGSDDISNFQSLCVTCN 187


>UniRef50_B0MFF1 Putative uncharacterized protein n=1 Tax=Anaerostipes caccae DSM
           14662 RepID=B0MFF1_9FIRM
          Length = 179

 Score = 64.0 bits (154), Expect = 5e-09,   Method: Composition-based stats.
 Identities = 20/61 (32%), Positives = 27/61 (44%), Gaps = 10/61 (16%)

Query: 192 DPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNC 251
              VK    ++S   C  C            P++EVHH+IP + G  DT +N   LC  C
Sbjct: 4   SEKVKEEARRRSGFRCVIC----------QEPFVEVHHIIPQNEGDEDTIENAAPLCSRC 53

Query: 252 H 252
           H
Sbjct: 54  H 54


>UniRef50_B9PFL0 Predicted protein (Fragment) n=2 Tax=cellular organisms
           RepID=B9PFL0_POPTR
          Length = 197

 Score = 64.0 bits (154), Expect = 5e-09,   Method: Composition-based stats.
 Identities = 26/114 (22%), Positives = 49/114 (42%), Gaps = 8/114 (7%)

Query: 155 ESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNA 214
           E+    +   L   ++   EG RK  +  R+     RD  +     ++    C++C    
Sbjct: 83  ENEGQEKPKYLDPDSIEAEEGYRK--DSSRMTST--RDRKLADARKKKDNYTCQSCKNQ- 137

Query: 215 PFYLNDGNPYLEVHHVIPLSSGGADT-TDNCVALCPNCHRELHYSKNAKELIEM 267
             Y  +    ++ HH+ P++ G  +T  ++ ++LCP CHR  H       L E+
Sbjct: 138 --YFVNDKYVIDCHHLNPINLGKRNTRIEDLISLCPTCHRIAHTRLPPYSLKEL 189


>UniRef50_A9VH89 HNH endonuclease n=3 Tax=Bacillus cereus group RepID=A9VH89_BACWK
          Length = 276

 Score = 64.0 bits (154), Expect = 6e-09,   Method: Composition-based stats.
 Identities = 28/130 (21%), Positives = 46/130 (35%), Gaps = 17/130 (13%)

Query: 134 DSFWA---SIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYV 190
           D ++     I+  EL E  +    E   +    K     +      RK    ++ +   +
Sbjct: 132 DDYYFYNEEIVESELDEKKRDIILEETKSFIDYKEQYVKIGDKTKRRKESSAQKKRIAIL 191

Query: 191 RDPMVKAWILQQSKGICENCGKNAPFYLNDGNP--YLEVHHVIPLSSGGADTTDNCVALC 248
            D              C+ CG    +   +      +EV H+I  S GG ++ DN   LC
Sbjct: 192 ED------------HTCQVCGFKEEYIKANNKKGWIIEVDHIIEKSKGGGESFDNLWVLC 239

Query: 249 PNCHRELHYS 258
           PNCH +    
Sbjct: 240 PNCHAKKTRG 249


>UniRef50_C4K5N9 Group II intron encoded reverse transcriptase n=10 Tax=Candidatus
           Hamiltonella defensa 5AT (Acyrthosiphon pisum)
           RepID=C4K5N9_HAMD5
          Length = 570

 Score = 63.6 bits (153), Expect = 7e-09,   Method: Composition-based stats.
 Identities = 24/85 (28%), Positives = 36/85 (42%), Gaps = 14/85 (16%)

Query: 187 KVYVRDPMVKAWIL---------QQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGG 237
           + Y R+   +             ++ KG C  C +     L++G   L VHH+ P + GG
Sbjct: 479 RDYWRNRQARKQPFIYGVKVNLYKRQKGYCPLCDQ----ELDNGEQ-LHVHHIQPKAEGG 533

Query: 238 ADTTDNCVALCPNCHRELHYSKNAK 262
            +   N   L  NCHR+LH  K   
Sbjct: 534 DNKLANLRLLHANCHRQLHSKKRKN 558


>UniRef50_D2S2Y4 HNH endonuclease n=1 Tax=Haloterrigena turkmenica DSM 5511
           RepID=D2S2Y4_9EURY
          Length = 221

 Score = 63.2 bits (152), Expect = 8e-09,   Method: Composition-based stats.
 Identities = 27/98 (27%), Positives = 39/98 (39%), Gaps = 13/98 (13%)

Query: 160 MRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYL 218
            R             G+R P    R + VY           +     C++CG+   P   
Sbjct: 5   ERQINSRYDDPDTYSGNRPPDWEARRKTVY-----------RHDNWTCQSCGRQSGPHAG 53

Query: 219 NDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELH 256
           N+G   L  HH++PLS GG++   N   LC  CH+  H
Sbjct: 54  NEGV-RLHAHHIVPLSEGGSNRLSNLETLCEPCHQNQH 90


>UniRef50_B9LX84 HNH endonuclease n=1 Tax=Halorubrum lacusprofundi ATCC 49239
           RepID=B9LX84_HALLT
          Length = 299

 Score = 63.2 bits (152), Expect = 9e-09,   Method: Composition-based stats.
 Identities = 17/61 (27%), Positives = 28/61 (45%), Gaps = 3/61 (4%)

Query: 196 KAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHREL 255
           +  + ++    C+ CG       + GN  L  HH  P S GG+    N   +C +CH ++
Sbjct: 13  RKKVYKRDNYRCQKCGSRG---GSRGNTELHAHHKKPKSKGGSHRFSNLTTVCKSCHEDI 69

Query: 256 H 256
           H
Sbjct: 70  H 70


>UniRef50_Q82RB7 Putative reverse transcriptase homolog; similar to GII intron n=1
           Tax=Streptomyces avermitilis RepID=Q82RB7_STRAW
          Length = 588

 Score = 63.2 bits (152), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 32/166 (19%), Positives = 59/166 (35%), Gaps = 29/166 (17%)

Query: 136 FWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVR---- 191
           +W +   G  S+    T +  L       + + TL + + S    E+E       R    
Sbjct: 426 YWGTFQPGRSSKWVFGTPEHYLPQASWMPIQRHTLVKDDASPDDQELEEYWGNRRRKRIQ 485

Query: 192 ---DPMVKAWILQQSKGICENCGKNAPFYLNDGNPY------------------LEVHHV 230
              +P     +  + +G+C  CG +    L DG  +                  + VHH+
Sbjct: 486 AVGEPKKILSLAYRQRGLCPRCGLD----LIDGVGFDPDDVQDWANWFTGSLRAIHVHHL 541

Query: 231 IPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQ 276
              S GG+D   N   +   CHR+ H      +       +++R++
Sbjct: 542 TYRSKGGSDHPSNLELIHTTCHRQAHAGDRKYDAHRRPQASLSRMR 587


>UniRef50_C6J8S5 Putative uncharacterized protein n=1 Tax=Ruminococcus sp.
           5_1_39BFAA RepID=C6J8S5_9FIRM
          Length = 285

 Score = 62.8 bits (151), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 36/196 (18%), Positives = 77/196 (39%), Gaps = 14/196 (7%)

Query: 93  PRDIRLKMCGYQAYFSRTGRKEIPSGNR--TKRILINVP-------GIYSDSFWASIIRG 143
           PR+  L     Q +F      ++   NR    R  I +P        IY+  +  + +  
Sbjct: 80  PRNGELSQALQQYFFKSMSYIKMIRENRDPKDRSYIKMPDGLKEYLAIYTTEYEDTFLLE 139

Query: 144 ELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVR--DPMVKAWILQ 201
            +++       +++  MR   +  +   + E     +E ++LQ V +R  +  +   +  
Sbjct: 140 PIAQDDFQVMKKAIQGMRERTVENEIEYEMEDKSSGIE-KKLQIVKIRKLNRKIGENLKL 198

Query: 202 QSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNA 261
                C+ CG+        G+   E HH+    +   +  +N + +CPN H  +H +   
Sbjct: 199 LYGYRCQICGQ--VIGEKYGSHIAEAHHIDYFVNSLNNDANNQMIVCPNHHSVIHDANPV 256

Query: 262 KELIEMLYVNINRLQK 277
            +   M+Y   N +++
Sbjct: 257 FDRRRMVYRFDNGVEE 272


>UniRef50_A1ZG09 Paclitaxel/taxanoid biosynthesis susceptibility protein TS1 n=5
           Tax=root RepID=A1ZG09_9SPHI
          Length = 453

 Score = 62.4 bits (150), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 26/115 (22%), Positives = 49/115 (42%), Gaps = 8/115 (6%)

Query: 145 LSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSK 204
           L E  Q     S + + V+    + +  P+   K  +    +  +     ++ ++L + K
Sbjct: 134 LVEQVQDCLPVSGVVLEVANFDIQKIKNPDIEGKQYQKGEQEGFW----NIREYVLHRDK 189

Query: 205 GICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSK 259
             C+N      +        L+VHH++  S GG DT +N + LC  CH   ++ K
Sbjct: 190 HSCQNPDCKNKYKGKI----LQVHHIVFKSMGGGDTPNNLITLCTKCHTSANHKK 240


>UniRef50_C1V6S3 HNH endonuclease n=1 Tax=Halogeometricum borinquense DSM 11551
           RepID=C1V6S3_9EURY
          Length = 357

 Score = 62.4 bits (150), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 21/73 (28%), Positives = 32/73 (43%), Gaps = 3/73 (4%)

Query: 192 DPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSG-GADTTDNCVALCPN 250
           DP  +  +L++ K  C+ CG+  P     G   L VHH+     G G    +N   LC +
Sbjct: 36  DPDTRDDVLEKYKHRCQACGRRGP--GKGGLATLHVHHIERDPDGMGEHDLENLTLLCRS 93

Query: 251 CHRELHYSKNAKE 263
           CH   H     ++
Sbjct: 94  CHSWFHQQSTPED 106


>UniRef50_B8I0D2 HNH endonuclease n=1 Tax=Clostridium cellulolyticum H10
           RepID=B8I0D2_CLOCE
          Length = 177

 Score = 62.4 bits (150), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 5/65 (7%)

Query: 197 AWILQQSKGICENCGKNAPFYLNDGNPY-----LEVHHVIPLSSGGADTTDNCVALCPNC 251
             IL +    C+ CG  A +    G        L+VHH+I +S GG D  +N + +C +C
Sbjct: 91  YRILCRDNFTCKECGLFAAYKNKHGLFVPIAVGLDVHHLIQVSEGGTDQQNNLITICNDC 150

Query: 252 HRELH 256
           H ++H
Sbjct: 151 HNQIH 155


>UniRef50_C1EM61 HNH endonuclease domain protein n=6 Tax=Bacillus cereus group
           RepID=C1EM61_BACC3
          Length = 267

 Score = 61.6 bits (148), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 18/71 (25%), Positives = 32/71 (45%), Gaps = 8/71 (11%)

Query: 196 KAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPL----SSGGADTTDNCVALCPNC 251
           +    ++ +  C+ CG +   Y  +    L VHH  P     S   A+   N ++LC +C
Sbjct: 119 RRRARKRDQYKCQICGIHEKEYGQE----LSVHHKKPFVYFESYEEANRLQNLISLCESC 174

Query: 252 HRELHYSKNAK 262
           HR++H  +   
Sbjct: 175 HRQVHKGEQHP 185


>UniRef50_Q8YJX6 All8554 protein n=2 Tax=Cyanobacteria RepID=Q8YJX6_ANASP
          Length = 335

 Score = 61.3 bits (147), Expect = 4e-08,   Method: Composition-based stats.
 Identities = 33/123 (26%), Positives = 50/123 (40%), Gaps = 4/123 (3%)

Query: 136 FWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSR-KPVEVERLQKVYVRDPM 194
               +I    +EL+Q  D E LL +     ++  L +  G   +P E+E  Q V VRD  
Sbjct: 154 LTHVLIDSWFNELTQE-DIEPLLQVNAFAELQDQLQRTGGKVYQPEELEDEQAVIVRDGA 212

Query: 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254
            +  ++      C  CG       + G   ++  H+ P S    D  DN +ALC N H  
Sbjct: 213 FRKIVVSTYNYRCAFCGLQ--ILDSLGQNIVDGSHIKPFSQFYDDRIDNGLALCKNHHWA 270

Query: 255 LHY 257
              
Sbjct: 271 FDR 273


>UniRef50_A5V9C7 HNH endonuclease n=1 Tax=Sphingomonas wittichii RW1
           RepID=A5V9C7_SPHWW
          Length = 426

 Score = 61.3 bits (147), Expect = 4e-08,   Method: Composition-based stats.
 Identities = 28/146 (19%), Positives = 57/146 (39%), Gaps = 10/146 (6%)

Query: 138 ASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKA 197
           A+    E+  L+      S L+               G  +  +V++      R+  ++ 
Sbjct: 264 AANRDAEIRRLANLFTGGSTLDFFDYPETVIAEVVESGFEEGNKVQKTHVTIERNSGLRK 323

Query: 198 WILQQSK--GICENCGKNAPFYLNDGNPYLEVHHVIPLSSGG-----ADTTDNCVALCPN 250
                +    +C+ C  +           +++HH++PLSSG        T D+ V LCP+
Sbjct: 324 -AFFAANPTTVCDVCNLDTARSYPWTERVMDLHHLLPLSSGTRVIGRGTTFDDLVPLCPS 382

Query: 251 CHRELH--YSKNAKELIEMLYVNINR 274
           CHR +H  Y +  +    + + + + 
Sbjct: 383 CHRAVHRYYGEWFRTTKRLDFHSRDE 408


>UniRef50_Q9R669 Group II SELF-splicing intron ORF (Fragments) n=1 Tax=Azotobacter
           vinelandii RepID=Q9R669_AZOVI
          Length = 86

 Score = 61.3 bits (147), Expect = 4e-08,   Method: Composition-based stats.
 Identities = 22/74 (29%), Positives = 28/74 (37%), Gaps = 9/74 (12%)

Query: 187 KVYVRDPMVKAWI----LQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTD 242
               R   ++A             C  C +   F          +HH+I    GG D  D
Sbjct: 18  TTIQRHKKIRAEANPYLWLGQSKRCPMCKQLITFETGWN-----IHHIIKRHMGGGDELD 72

Query: 243 NCVALCPNCHRELH 256
           N V L PNCHR+LH
Sbjct: 73  NLVLLHPNCHRQLH 86


>UniRef50_B5W3B8 HNH endonuclease n=1 Tax=Arthrospira maxima CS-328
           RepID=B5W3B8_SPIMA
          Length = 80

 Score = 60.9 bits (146), Expect = 4e-08,   Method: Composition-based stats.
 Identities = 21/71 (29%), Positives = 29/71 (40%), Gaps = 8/71 (11%)

Query: 194 MVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHR 253
             +  + Q+    CE CGK               HHVI  S GG     N + LCP+CHR
Sbjct: 15  KAQKLVKQRDGNECEICGKIGEI--------AHGHHVIAYSDGGPADLTNMMTLCPDCHR 66

Query: 254 ELHYSKNAKEL 264
             H  +   ++
Sbjct: 67  AYHNGEIKVDI 77


>UniRef50_B9ZDV6 HNH endonuclease n=1 Tax=Natrialba magadii ATCC 43099
           RepID=B9ZDV6_NATMA
          Length = 282

 Score = 60.9 bits (146), Expect = 5e-08,   Method: Composition-based stats.
 Identities = 18/61 (29%), Positives = 29/61 (47%), Gaps = 8/61 (13%)

Query: 196 KAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHREL 255
           +   L++    C  CG +           L+ HH++P S+GG D  +N + LC  CH  +
Sbjct: 63  RQQTLRRDNYACTRCGADDRT--------LQAHHIVPRSAGGPDELENLLTLCRPCHGVI 114

Query: 256 H 256
           H
Sbjct: 115 H 115


>UniRef50_Q5YZQ8 Putative uncharacterized protein n=1 Tax=Nocardia farcinica
           RepID=Q5YZQ8_NOCFA
          Length = 130

 Score = 60.9 bits (146), Expect = 5e-08,   Method: Composition-based stats.
 Identities = 22/68 (32%), Positives = 27/68 (39%), Gaps = 12/68 (17%)

Query: 193 PMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGA-----DTTDNCVAL 247
           P V   +  ++ G CE C    P          EVHH IP   GG      +     V L
Sbjct: 21  PAVLMLVKSRAGGRCERCAAPIPTTA-------EVHHRIPRGMGGTRDPRVNRPSALVVL 73

Query: 248 CPNCHREL 255
           CP CHR +
Sbjct: 74  CPQCHRRI 81


>UniRef50_B6JPE5 Restriction endonuclease n=4 Tax=Helicobacter pylori
           RepID=B6JPE5_HELP2
          Length = 407

 Score = 60.9 bits (146), Expect = 5e-08,   Method: Composition-based stats.
 Identities = 28/141 (19%), Positives = 49/141 (34%), Gaps = 16/141 (11%)

Query: 153 DDESLLNMRVSKLIKKTLSQP--EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENC 210
                 +  +  + ++ L+    E  R+ +   +  + + RD  +  +    +  +C  C
Sbjct: 240 SFTERTHFYLKNVYQQDLNDKSIERLREQLGWIQKSEEFRRDSKIINFYRLSTPNVCSAC 299

Query: 211 GKNAPFY-------------LNDGNPYLEVHHVIPL-SSGGADTTDNCVALCPNCHRELH 256
             +                     + Y E+HHVI L      D   N   LCP CHR L 
Sbjct: 300 CGDYDIKERSFISLPLYQITQKPDSYYTEIHHVISLGKDQELDVLANLAKLCPACHRALK 359

Query: 257 YSKNAKELIEMLYVNINRLQK 277
              + +E  + L  NI    K
Sbjct: 360 KGSSEEEFQKRLIRNILNRNK 380


>UniRef50_B0MB23 Putative uncharacterized protein n=1 Tax=Anaerostipes caccae DSM
           14662 RepID=B0MB23_9FIRM
          Length = 99

 Score = 60.5 bits (145), Expect = 6e-08,   Method: Composition-based stats.
 Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 15/85 (17%)

Query: 182 VERLQKVYVRDPMVK-----AWILQQSKGI-----CENCGKNAPFYLNDGNPYLEVHHVI 231
           + +  + Y RD  V+     AW   +   +     CE C     F      P  EVHH +
Sbjct: 1   MNQSYEKYGRDKAVRRRYGRAWKRIRDSYVKEHPFCEIC-----FEKGIIVPVDEVHHKL 55

Query: 232 PLSSGGADTTDNCVALCPNCHRELH 256
           PLS GG    DN ++LC +CH ++H
Sbjct: 56  PLSEGGNHNKDNLISLCKSCHAKIH 80


>UniRef50_B7IHZ5 HNH endonuclease domain protein n=1 Tax=Thermosipho africanus
           TCF52B RepID=B7IHZ5_THEAB
          Length = 423

 Score = 60.5 bits (145), Expect = 6e-08,   Method: Composition-based stats.
 Identities = 24/79 (30%), Positives = 33/79 (41%), Gaps = 9/79 (11%)

Query: 194 MVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHR 253
            V+ + L ++    E  GK            LEVHH+IP S GG D   N + L    H+
Sbjct: 181 DVREYCLWRAGYKSELSGK---------KGILEVHHIIPRSKGGTDNPSNLIVLTAEEHK 231

Query: 254 ELHYSKNAKELIEMLYVNI 272
            LH  K      ++  V I
Sbjct: 232 ALHEGKIKIPRSKLEKVRI 250


>UniRef50_Q82H00 Putative uncharacterized protein n=1 Tax=Streptomyces avermitilis
           RepID=Q82H00_STRAW
          Length = 515

 Score = 60.1 bits (144), Expect = 7e-08,   Method: Composition-based stats.
 Identities = 21/84 (25%), Positives = 29/84 (34%), Gaps = 4/84 (4%)

Query: 178 KPVEVER-LQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLS-- 234
            PV     + +   RD  V+  +       C+ C     F       Y E  H+  L   
Sbjct: 388 TPVRRRAAIVQAQDRDSQVRRQVKVWYDNTCQFCRTKIEF-PAQPFSYSEGAHIQALGAP 446

Query: 235 SGGADTTDNCVALCPNCHRELHYS 258
             G D  +N + LCPNCH      
Sbjct: 447 HNGPDRVENMLCLCPNCHIRFDMG 470


>UniRef50_A5N0L8 Phage-related protein n=15 Tax=Bacteria RepID=A5N0L8_CLOK5
          Length = 119

 Score = 60.1 bits (144), Expect = 8e-08,   Method: Composition-based stats.
 Identities = 26/102 (25%), Positives = 43/102 (42%), Gaps = 19/102 (18%)

Query: 164 KLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVK-----AWILQQSKGI-----CENCGKN 213
           +L  +   +    ++    E+    Y RDP  +     AW   + + I     CE C + 
Sbjct: 16  ELTDRGFCKEHAKKEAARYEK----YDRDPATRKRYGRAWKRIRDRYIAAHPLCEECKRQ 71

Query: 214 APFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHREL 255
                    P  EVHH++PL+ GG     N ++LC +CH  +
Sbjct: 72  GKL-----TPATEVHHILPLARGGTHDRSNLMSLCTSCHSTI 108


>UniRef50_Q2S547 Putative uncharacterized protein n=1 Tax=Salinibacter ruber DSM
           13855 RepID=Q2S547_SALRD
          Length = 299

 Score = 60.1 bits (144), Expect = 8e-08,   Method: Composition-based stats.
 Identities = 29/122 (23%), Positives = 48/122 (39%), Gaps = 6/122 (4%)

Query: 143 GELSELSQPTDDESLLNMRVSKLIKKTL---SQPEGSRKPVEVERLQKVYVR-DPMVKAW 198
           G   ++ Q   ++S L   +++L+  +    S  E     V ++       R DP  +  
Sbjct: 117 GFSDDIHQAFRNDSELRRGIARLLLSSHFPTSLHEDIATAVSLDLEGAASERRDPEFRTQ 176

Query: 199 ILQQSKGICENCGKNAPFYLNDGNPY-LEVHHVIPLSSGGADTTDNCVALCPNCHRELHY 257
           +LQ  +  C  CG N       G P  +E  H+    + G D   N +ALC   H+ L  
Sbjct: 177 VLQAYQYRCAICGFNLQ-LGMSGTPIGVEAAHIKWKQARGPDEISNGIALCALHHKMLDK 235

Query: 258 SK 259
             
Sbjct: 236 GA 237


>UniRef50_Q21AN9 HNH endonuclease n=1 Tax=Rhodopseudomonas palustris BisB18
           RepID=Q21AN9_RHOPB
          Length = 200

 Score = 59.7 bits (143), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 19/53 (35%), Positives = 29/53 (54%), Gaps = 3/53 (5%)

Query: 225 LEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKE---LIEMLYVNINR 274
           L++HH+  +S+GG D + N +ALCP CH   H      E   + + + V I R
Sbjct: 39  LDMHHIWEVSAGGTDDSSNLIALCPTCHALYHRGTIKAESIYVYKSMIVAITR 91


>UniRef50_C0EP64 Putative uncharacterized protein n=1 Tax=Neisseria flavescens
           NRL30031/H210 RepID=C0EP64_NEIFL
          Length = 106

 Score = 59.7 bits (143), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 21/70 (30%), Positives = 35/70 (50%), Gaps = 6/70 (8%)

Query: 194 MVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHR 253
            ++  +L + +  C  CG+      +D     E  H++PL+ GGAD  +N   LC +CH 
Sbjct: 39  SLRESVLIRDQYQCRQCGR--VVLPSD----AECDHIVPLADGGADDVENLQTLCKDCHL 92

Query: 254 ELHYSKNAKE 263
           E   S+N + 
Sbjct: 93  EKSVSENRRR 102


>UniRef50_D1S1E3 HNH nuclease n=1 Tax=Micromonospora aurantiaca ATCC 27029
           RepID=D1S1E3_9ACTO
          Length = 496

 Score = 58.9 bits (141), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 25/95 (26%), Positives = 35/95 (36%), Gaps = 6/95 (6%)

Query: 166 IKKTLSQPEGSRKPVEVE-RLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPY 224
           ++  L  P GS  P E +       VR       + +     C+ CG        DG  Y
Sbjct: 358 LEPDLLTPTGSGDPAERKLVTVDRIVRSSRYAKAVKRLYDHRCQICGVR--LATRDG-YY 414

Query: 225 LEVHHVIPLSS--GGADTTDNCVALCPNCHRELHY 257
            E  H+  L     G D   N + LCPN H +  +
Sbjct: 415 SEAAHIRGLGKPHDGTDDLSNLLCLCPNHHTQFDF 449


>UniRef50_B1I905 HNH endonuclease domain protein n=3 Tax=Streptococcus pneumoniae
           RepID=B1I905_STRPI
          Length = 326

 Score = 58.9 bits (141), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 31/148 (20%), Positives = 59/148 (39%), Gaps = 17/148 (11%)

Query: 106 YFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKL 165
           YFS+   KE+          I++P I  D + + I     +  +       L N    + 
Sbjct: 189 YFSKDLMKELD---------IHLPDIKVD-YTSYIFEYVSAGGNSSQKTTILFNGETVEA 238

Query: 166 IKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYL 225
             + +++   S++  + +R          ++  I ++    C+ C  +           L
Sbjct: 239 TAEYIAKKIKSKQTAQAQRSLMT----NKLRTQIKERDHYTCQICAAST---AEQSLLLL 291

Query: 226 EVHHVIPLSSGGADTTDNCVALCPNCHR 253
           E+ H++P+S GG  T DN   LC  C+R
Sbjct: 292 EIDHIVPVSKGGLSTPDNLQTLCWKCNR 319


>UniRef50_B0MB74 Putative uncharacterized protein n=1 Tax=Anaerostipes caccae DSM
           14662 RepID=B0MB74_9FIRM
          Length = 255

 Score = 58.6 bits (140), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 19/87 (21%), Positives = 43/87 (49%), Gaps = 7/87 (8%)

Query: 192 DPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNC 251
              ++  + ++    C+ CG++AP      +  LEV H+ P+++GG +   N +  C +C
Sbjct: 8   SKKIRFEVFKRDSFTCQYCGRSAP------DVILEVDHINPVANGGDNDIMNLITSCRDC 61

Query: 252 HRELHYSKNAK-ELIEMLYVNINRLQK 277
           +R    ++ +  E I+     ++ L +
Sbjct: 62  NRGKGKTELSDSETIKKKKEQLDELNE 88


>UniRef50_A3HSL8 Putative uncharacterized protein n=1 Tax=Algoriphagus sp. PR1
           RepID=A3HSL8_9SPHI
          Length = 316

 Score = 58.6 bits (140), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 25/122 (20%), Positives = 48/122 (39%), Gaps = 2/122 (1%)

Query: 134 DSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDP 193
           DS    +++      S+     +    +  K +++ +         ++V   + VYVR+ 
Sbjct: 135 DSMRNMLVKFYFPSSSEHYFRANREQGKYLKEVQQYVLNEVPKVMRLQVAEEEVVYVRNW 194

Query: 194 MVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHR 253
             K  + +  +  C   G        +G   ++  H++P S    D   N +ALCPN HR
Sbjct: 195 TFKKLVPKVYQSTCAISGM--KVGSINGRSLIDACHIVPFSQDQDDRISNGIALCPNLHR 252

Query: 254 EL 255
             
Sbjct: 253 AF 254


>UniRef50_C6A463 Putative uncharacterized protein n=1 Tax=Thermococcus sibiricus MM
           739 RepID=C6A463_THESM
          Length = 184

 Score = 58.6 bits (140), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 23/90 (25%), Positives = 38/90 (42%), Gaps = 11/90 (12%)

Query: 190 VRDP--MVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVAL 247
            R+    ++  I++     CE CG+     ++    Y+  HH+ P+  GG  T  N + L
Sbjct: 24  ERNITGAMRRDIIEVVGRKCEYCGR----RVSTTAGYI--HHIKPIREGGKTTPSNIIVL 77

Query: 248 CPNCHRELHYSKNAKELIEMLYVNINRLQK 277
           C  CHR    + NA    + L   +    K
Sbjct: 78  CGTCHR---NADNAIISRKELKEKVRSRSK 104


>UniRef50_Q8U2D9 Putative uncharacterized protein n=1 Tax=Pyrococcus furiosus
           RepID=Q8U2D9_PYRFU
          Length = 326

 Score = 58.6 bits (140), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 37/140 (26%), Positives = 51/140 (36%), Gaps = 38/140 (27%)

Query: 142 RGELSELS----QPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDP---- 193
              L ELS    +   D S   +  S   K      +G  +P  V    +  VRD     
Sbjct: 58  EDFLDELSKNPIEVVIDFSFKKIVESNEEKIRREIIQGFTRPFGVISRIQEKVRDAIMKE 117

Query: 194 --------------MVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGA- 238
                          ++  +L+++   C  C          G  YLEVHHV     G   
Sbjct: 118 IEEEIEKEQASTPEHLRKVVLERNNYRCSVC----------GYGYLEVHHV----DGNIL 163

Query: 239 -DTTDNCVALCPNCHRELHY 257
            +T DN V LC  CHR++HY
Sbjct: 164 NNTLDNLVTLCRRCHRKVHY 183



 Score = 45.1 bits (105), Expect = 0.003,   Method: Composition-based stats.
 Identities = 14/78 (17%), Positives = 28/78 (35%), Gaps = 12/78 (15%)

Query: 200 LQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSK 259
           +++    C  C             YL++H+            +N + LC  CH  LH  +
Sbjct: 1   MERDGYKCRICDH----------SYLDIHYKDGNVENK--NLENLIVLCKQCHYRLHQKE 48

Query: 260 NAKELIEMLYVNINRLQK 277
             + + +     ++ L K
Sbjct: 49  RMESIKQAFEDFLDELSK 66


>UniRef50_A0YZ73 RNA-directed DNA polymerase n=1 Tax=Lyngbya sp. PCC 8106
           RepID=A0YZ73_9CYAN
          Length = 179

 Score = 58.6 bits (140), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 31/125 (24%), Positives = 52/125 (41%), Gaps = 10/125 (8%)

Query: 131 IYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSR---KPVEVERLQK 187
           I  D +W ++     +      D   L     + +++ T  + E S          + + 
Sbjct: 43  INKDKYWRTVGNK--NWCFSTEDGLELFTHSSTPIVRHTKVKGEASPFNGDWTYWSKRRG 100

Query: 188 VYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVAL 247
            Y + P   + ++++ KGIC +CG    F   D    +EV H+ P S GG D  DN   L
Sbjct: 101 KYPKTPKRVSRLIKKQKGICPHCGLY--FTSTDS---VEVDHIQPTSLGGKDIYDNLQLL 155

Query: 248 CPNCH 252
             +CH
Sbjct: 156 HKHCH 160


>UniRef50_C0GPK5 Restriction endonuclease n=1 Tax=Desulfonatronospira thiodismutans
           ASO3-1 RepID=C0GPK5_9DELT
          Length = 318

 Score = 58.2 bits (139), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 24/111 (21%), Positives = 39/111 (35%), Gaps = 10/111 (9%)

Query: 148 LSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGIC 207
           L + ++++         L     + P GS KP  +        RD   +  ++      C
Sbjct: 159 LLEASENQQAYEYSRKLLKAAEKTLPYGSDKPANI--------RDQGFRKAVMTLYAHRC 210

Query: 208 ENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258
             CG        +G+  +E  H+ P S    D   N +ALC  CH      
Sbjct: 211 ALCGIRM--LTPEGHTIVEAAHIRPWSDTSDDRPANGMALCRLCHWSFDRG 259


>UniRef50_Q19YE9 Gp104 n=4 Tax=unclassified Siphoviridae RepID=Q19YE9_9CAUD
          Length = 108

 Score = 58.2 bits (139), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 19/60 (31%), Positives = 27/60 (45%), Gaps = 4/60 (6%)

Query: 193 PMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252
             ++    ++    C++CG  A      G+  L   H+ P S GG DT DN   LC  CH
Sbjct: 40  HWLQRATFRRDNWTCQSCGHTAT----PGSGQLHADHIQPRSRGGTDTLDNMRTLCKACH 95


>UniRef50_A0PZM8 HNH endonuclease domain protein n=3 Tax=Bacteria RepID=A0PZM8_CLONN
          Length = 299

 Score = 58.2 bits (139), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 3/67 (4%)

Query: 194 MVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHR 253
            ++  I ++    C+ CG +     ++ N  LE+ H+IP+S GG  T  N   LC  C+R
Sbjct: 236 KLREKIKKRDNYTCQKCGLST---RDEKNLLLEIDHIIPISKGGMSTEKNLQTLCWKCNR 292

Query: 254 ELHYSKN 260
           +     N
Sbjct: 293 KKGAKLN 299


>UniRef50_Q0F8W7 Putative uncharacterized protein n=1 Tax=Rhodobacterales bacterium
           HTCC2255 RepID=Q0F8W7_9RHOB
          Length = 228

 Score = 57.8 bits (138), Expect = 4e-07,   Method: Composition-based stats.
 Identities = 46/207 (22%), Positives = 74/207 (35%), Gaps = 44/207 (21%)

Query: 48  IERLVDSGVSQVVVYLASSSVRKHMHSLDERKIHPGEYFTLIGNSPRDIRLKMCGYQAYF 107
           IER+ D   S+  +    +  +KH++S DE        F  I N  +             
Sbjct: 57  IERIFDGSFSKACIAAGVNIKKKHIYSFDE-------LFEHIENVAK------------- 96

Query: 108 SRTGRKEIPS-GNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLI 166
               R +IPS G+  K    +   +  D++     R   S  +         N ++SK  
Sbjct: 97  ---WRNQIPSIGDLKKYNKKHNTSLTYDAY----ARRWGSWKNFLKVFVQFKNNQISKHE 149

Query: 167 KKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLE 226
               S+    RK +               +A +L +    C +CG        D    L 
Sbjct: 150 LIDASKKSLRRKAISKRS-----------RAEVLARDNYKCSDCG-----RTVDDGCKLH 193

Query: 227 VHHVIPLSSGGADTTDNCVALCPNCHR 253
           VHH IP S GG +  +N +  C +C+ 
Sbjct: 194 VHHKIPASHGGQNNLENLITNCADCNM 220


>UniRef50_C6WB78 Restriction endonuclease-like protein n=1 Tax=Actinosynnema mirum
           DSM 43827 RepID=C6WB78_ACTMD
          Length = 251

 Score = 57.8 bits (138), Expect = 4e-07,   Method: Composition-based stats.
 Identities = 30/128 (23%), Positives = 43/128 (33%), Gaps = 22/128 (17%)

Query: 139 SIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKP-VEVERLQKVYVRDPMVKA 197
           + +   L+ L     D + +        K  + +     +P    ER      R   V A
Sbjct: 76  ATVTRLLTGLGFTVVDRAQVPAPPVDAEKVVVWERGRVLEPAPRQERTTSAVQRLRYVAA 135

Query: 198 WILQQSKGICENCG----------KNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVAL 247
            +    +  C+ CG           NA      G P    HH       G D TDN + L
Sbjct: 136 LVKAIHEDRCQFCGTRLDLGYGHFSNAAHIRALGAP----HH-------GPDHTDNVLCL 184

Query: 248 CPNCHREL 255
           CPNCH + 
Sbjct: 185 CPNCHAQF 192


>UniRef50_B0SF14 HNH nuclease n=4 Tax=Bacteria RepID=B0SF14_LEPBA
          Length = 97

 Score = 57.8 bits (138), Expect = 4e-07,   Method: Composition-based stats.
 Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 8/83 (9%)

Query: 184 RLQKVYVRDPMVKAWIL-QQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTD 242
           R ++   +D    AW   ++S GIC  CGK            L + H+IPL  GG     
Sbjct: 19  RRERKKAKDLKNTAWWKNKRSNGICHYCGKKFKVEE------LTMDHLIPLIRGGKSVKA 72

Query: 243 NCVALCPNCH-RELHYSKNAKEL 264
           N V  C  C+ ++ H     KE 
Sbjct: 73  NLVPACKECNFKKKHSLPFEKEF 95


>UniRef50_A3Z7E0 HIT family protein n=6 Tax=Synechococcus RepID=A3Z7E0_9SYNE
          Length = 314

 Score = 57.4 bits (137), Expect = 5e-07,   Method: Composition-based stats.
 Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 6/59 (10%)

Query: 194 MVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252
            ++  +  ++KG CE CG +           LEV H+IP + GG+D   N  ALC  C+
Sbjct: 116 SIRYRVFTRAKGRCECCGAHE------HQAALEVDHIIPKNHGGSDDISNFQALCFRCN 168


>UniRef50_B2IX42 HNH endonuclease n=18 Tax=Cyanobacteria RepID=B2IX42_NOSP7
          Length = 95

 Score = 57.4 bits (137), Expect = 5e-07,   Method: Composition-based stats.
 Identities = 18/62 (29%), Positives = 33/62 (53%), Gaps = 6/62 (9%)

Query: 193 PMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252
           P VK ++ ++ K  C++CGK           ++ + H+IPL+ GG +   N   LC  C+
Sbjct: 25  PEVKKYVFERDKYQCQSCGKTTT------ETHISIDHIIPLARGGQNDISNLQTLCLTCN 78

Query: 253 RE 254
           ++
Sbjct: 79  QQ 80


>UniRef50_B0VJM1 Putative ATP dependant helicase yprA n=1 Tax=Candidatus Cloacamonas
           acidaminovorans RepID=B0VJM1_9BACT
          Length = 863

 Score = 57.0 bits (136), Expect = 6e-07,   Method: Composition-based stats.
 Identities = 24/61 (39%), Positives = 27/61 (44%), Gaps = 13/61 (21%)

Query: 197 AWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSS----GGADTTDNCVALCPNCH 252
             I Q+    C NCG             LEVHH+IP         A+  DN VALCP CH
Sbjct: 688 EQIRQRDNYHCRNCGATGD---------LEVHHIIPFRRFEDPAEANEPDNLVALCPRCH 738

Query: 253 R 253
           R
Sbjct: 739 R 739


>UniRef50_B9ZCI1 HNH endonuclease n=1 Tax=Natrialba magadii ATCC 43099
           RepID=B9ZCI1_NATMA
          Length = 143

 Score = 57.0 bits (136), Expect = 6e-07,   Method: Composition-based stats.
 Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 5/63 (7%)

Query: 194 MVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHR 253
            + A + ++ +  C NC     +   D    L+ HH++P S GG+    N + LC  CH 
Sbjct: 8   DIVAAVRERDRCQCMNC-----YREEDEVAALDTHHIVPRSHGGSHRLGNLITLCRQCHN 62

Query: 254 ELH 256
             H
Sbjct: 63  AAH 65


>UniRef50_A1REN7 HNH nuclease n=1 Tax=Shewanella sp. W3-18-1 RepID=A1REN7_SHESW
          Length = 387

 Score = 57.0 bits (136), Expect = 6e-07,   Method: Composition-based stats.
 Identities = 23/92 (25%), Positives = 40/92 (43%), Gaps = 6/92 (6%)

Query: 183 ERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTD 242
           ++L K  +    ++A ++ +    C  C  +           LE+  + P + GG+ T +
Sbjct: 4   QKLNKRRIPSVAMRAKLIAKHNNQCAMCTISGEEIP------LELASITPFNEGGSMTEE 57

Query: 243 NCVALCPNCHRELHYSKNAKELIEMLYVNINR 274
           N + LCPNCHR +       E +  LY  I  
Sbjct: 58  NFLLLCPNCHRYMTMGPKEIEFVNFLYQVIKE 89


>UniRef50_D0LCK0 HNH endonuclease n=3 Tax=Gordonia bronchialis DSM 43247
           RepID=D0LCK0_GORB4
          Length = 418

 Score = 57.0 bits (136), Expect = 7e-07,   Method: Composition-based stats.
 Identities = 18/65 (27%), Positives = 30/65 (46%), Gaps = 9/65 (13%)

Query: 193 PMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252
           P ++  ++ + +  C  CG  A         +   HH+   S GG    DN   LCP+CH
Sbjct: 320 PKLRKALIARDQC-CIKCGAPA--------GWTHAHHITFYSHGGKTVLDNGCLLCPSCH 370

Query: 253 RELHY 257
            ++H+
Sbjct: 371 TDVHH 375


>UniRef50_Q4C417 HNH endonuclease n=3 Tax=Crocosphaera watsonii WH 8501
           RepID=Q4C417_CROWT
          Length = 104

 Score = 57.0 bits (136), Expect = 7e-07,   Method: Composition-based stats.
 Identities = 25/68 (36%), Positives = 37/68 (54%), Gaps = 5/68 (7%)

Query: 185 LQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNC 244
           ++  Y   P   + +L++ KGIC  C ++  F   D    +EV H+IP S GG DT +N 
Sbjct: 11  IRGAYTGTPNRVSKLLKKQKGICPQCKQH--FTPED---LIEVDHIIPKSKGGKDTYNNL 65

Query: 245 VALCPNCH 252
            AL  +CH
Sbjct: 66  QALHRHCH 73


>UniRef50_Q94Z24 Orf568 n=1 Tax=Pylaiella littoralis RepID=Q94Z24_PYLLI
          Length = 568

 Score = 57.0 bits (136), Expect = 7e-07,   Method: Composition-based stats.
 Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 5/67 (7%)

Query: 200 LQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSK 259
           L++ K  C+ C +        G   +E+HH+ P S GG D   N V L   CH++L ++K
Sbjct: 498 LRRDKYKCKVCNEYI-----CGEDKVEIHHIKPKSLGGDDAISNNVVLHAECHKQLTHTK 552

Query: 260 NAKELIE 266
           +   L  
Sbjct: 553 SRSLLAR 559


>UniRef50_C0ZFI4 Putative uncharacterized protein n=1 Tax=Brevibacillus brevis NBRC
           100599 RepID=C0ZFI4_BREBN
          Length = 120

 Score = 56.6 bits (135), Expect = 8e-07,   Method: Composition-based stats.
 Identities = 26/96 (27%), Positives = 36/96 (37%), Gaps = 14/96 (14%)

Query: 170 LSQPEGSRKPVEVERLQKVYVR---DPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLE 226
            ++     KP    R++K   R      V A + ++ KG C  C K      +     LE
Sbjct: 4   FNEVRAVPKPTFKRRVKKQKDRGKITSKVLAEVWERDKGCCVLCKK-----SSKQVWTLE 58

Query: 227 VHHVIPLSSGGADTTDNCVALC-P-----NCHRELH 256
            HH+I  S GG     N    C P      CH + H
Sbjct: 59  GHHIIFRSQGGTGEPWNVALACGPVTQSGTCHWKAH 94


>UniRef50_Q7GEU5 Putative uncharacterized protein (Fragment) n=3 Tax=Candida
           parapsilosis RepID=Q7GEU5_CANPA
          Length = 933

 Score = 56.6 bits (135), Expect = 9e-07,   Method: Composition-based stats.
 Identities = 17/73 (23%), Positives = 32/73 (43%), Gaps = 1/73 (1%)

Query: 192 DPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGA-DTTDNCVALCPN 250
           +   K  +L +   +C  C              L +HH+ P++ GGA +  DN + +   
Sbjct: 856 NAPFKQKLLIRQNNLCPVCQSTLTESSVGWTNVLHIHHINPIAKGGARNKLDNLILVHSW 915

Query: 251 CHRELHYSKNAKE 263
           CH++LH    + +
Sbjct: 916 CHKDLHRVNRSHK 928


>UniRef50_Q07U56 Restriction endonuclease-like protein n=2 Tax=Bradyrhizobiaceae
           RepID=Q07U56_RHOP5
          Length = 289

 Score = 56.3 bits (134), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 21/83 (25%), Positives = 35/83 (42%), Gaps = 8/83 (9%)

Query: 184 RLQKVYVRDPMVKAWILQQSKG-ICEN--CGKNAP-FYLNDGNPYLEVHHVIPLSSGGAD 239
           R ++  +R   ++A + + S    CE   CG +    Y   G+ +  VHH+ PLS    +
Sbjct: 192 RRREASLRTKKIQAALWENSGVLRCEVPRCGFDFKNKYGELGSEFAHVHHLKPLSESPIE 251

Query: 240 T----TDNCVALCPNCHRELHYS 258
                      +C NCH  +H  
Sbjct: 252 GRVVGLHEFAIVCANCHAMIHRG 274


>UniRef50_B6VWC0 Putative uncharacterized protein n=1 Tax=Bacteroides dorei DSM
           17855 RepID=B6VWC0_9BACE
          Length = 284

 Score = 56.3 bits (134), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 21/117 (17%), Positives = 45/117 (38%), Gaps = 4/117 (3%)

Query: 143 GELSELSQPTDDESLLNMRVSKLIKKTLSQ---PEGSRKPVEVERLQKVYVRDPMVKAWI 199
            E   ++     E+   +    + +K+       + +   V+     K+   D  V   +
Sbjct: 140 WEAVPITSSDYQETKKQLSELAITEKSFEDMLLTDNNATIVQENHFVKIRKLDRNVCLNL 199

Query: 200 LQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELH 256
            +     C+ CG+       +  P ++ HH+   +    +  +N + LCPN HR +H
Sbjct: 200 KKLYNFRCQICGQLISAPYGN-KPVVDAHHIEFFTQSLNNNYNNVMILCPNHHRIVH 255


>UniRef50_A3CWM7 HNH endonuclease n=1 Tax=Methanoculleus marisnigri JR1
           RepID=A3CWM7_METMJ
          Length = 120

 Score = 56.3 bits (134), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 29/121 (23%), Positives = 47/121 (38%), Gaps = 26/121 (21%)

Query: 154 DESLLNMRVSKLIKKTLSQPEGSRKPV---------------EVERLQKVYVRDP---MV 195
            +   ++   KL K TL +    ++PV                +++  +   R P    +
Sbjct: 6   KKDPFDLEPIKLPKLTLPKTPKIKEPVLPKITWEGLGFTGLNTIDQFDEKKKRVPIPQSI 65

Query: 196 KAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHREL 255
           K  IL + KG CE C  +      D      +HH         +   N + +CPNCHR+L
Sbjct: 66  KTEILLRCKGKCEKCHTSLKGLKPD------IHHKNR--DPADNRKVNLLVVCPNCHRKL 117

Query: 256 H 256
           H
Sbjct: 118 H 118


>UniRef50_C7NQ66 HNH endonuclease n=2 Tax=Halobacteriaceae RepID=C7NQ66_HALUD
          Length = 277

 Score = 55.9 bits (133), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 13/74 (17%)

Query: 194 MVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPL---------SSGGADTTDNC 244
            V+   L++ +  C +CG  +     +     +VHH++P+             A T DN 
Sbjct: 187 AVRREALERDEYECVHCGTGSDSLGRNP----DVHHIVPVRAFVTSDRHEKTDAHTIDNV 242

Query: 245 VALCPNCHRELHYS 258
           V+LCP+CHR   + 
Sbjct: 243 VSLCPSCHRRAEFG 256


>UniRef50_B8F0E2 Restriction endonuclease-like protein n=1 Tax=Thauera sp. MZ1T
           RepID=B8F0E2_THASP
          Length = 333

 Score = 55.9 bits (133), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 23/108 (21%), Positives = 36/108 (33%), Gaps = 2/108 (1%)

Query: 151 PTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENC 210
           P  D+ L +    +L ++         +        K   R    +  ++      C  C
Sbjct: 169 PLADDDLTDAFKEELEREGKPFKLIDDEAGTTTVTVKKVARALAFRTIVIALYDERCAVC 228

Query: 211 GKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258
           G+        G   +E  HV+P S  GAD   N V+LC   H      
Sbjct: 229 GEG--LKSPAGATEVEAAHVVPRSQFGADDARNGVSLCKAHHWAFDRG 274


>UniRef50_C7Q4G6 HNH endonuclease n=1 Tax=Catenulispora acidiphila DSM 44928
           RepID=C7Q4G6_CATAD
          Length = 552

 Score = 55.9 bits (133), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 22/76 (28%), Positives = 32/76 (42%), Gaps = 6/76 (7%)

Query: 192 DPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNC 251
              ++  IL++    C  CG  AP         L V HV+P++ GG D   N VA C  C
Sbjct: 4   SKRLRYEILRRDNHTCRYCGATAPTVP------LRVDHVVPVALGGTDDATNLVASCEPC 57

Query: 252 HRELHYSKNAKELIEM 267
           +     +     L+E 
Sbjct: 58  NSGKTSTAPDSPLVEQ 73


>UniRef50_Q3Z844 HNH endonuclease family protein n=1 Tax=Dehalococcoides ethenogenes
           195 RepID=Q3Z844_DEHE1
          Length = 182

 Score = 55.5 bits (132), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 22/99 (22%), Positives = 44/99 (44%), Gaps = 12/99 (12%)

Query: 164 KLIKKTLSQPEGSRKPVEVERLQKVYVRDP---MVKAWILQQSKGICENCGKNAPFYLND 220
           + ++    Q   S     +    +++ R+P    ++  +L++++  CEN   N       
Sbjct: 66  RSVRSKAGQVVKSTAEKIIYDSTEIHRREPVPNKMRKRVLERAENRCENHDCNYT----- 120

Query: 221 GNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSK 259
           G P  E+HH+    +   +   N +ALC NCH + H+  
Sbjct: 121 GIP--EIHHIDD--NNSNNDPRNLIALCRNCHGDAHHGN 155


>UniRef50_B0JFS6 HNH endonuclease n=2 Tax=Cyanobacteria RepID=B0JFS6_MICAN
          Length = 147

 Score = 55.5 bits (132), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 6/84 (7%)

Query: 196 KAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHREL 255
           +  + Q++   CE C  +  + +      L++ H+ PL+ GGA+T DN    C  C++  
Sbjct: 9   RQKVKQRAGNRCEYCLSHQDYIM----GRLQIDHIQPLAKGGANTEDNLCLACELCNQYK 64

Query: 256 HYSKNAKELIEMLYVNI--NRLQK 277
                A +    + V++   RLQK
Sbjct: 65  WTQTEAIDPKSEVLVSLFNPRLQK 88


>UniRef50_D1VPN1 HNH endonuclease n=1 Tax=Frankia sp. EuI1c RepID=D1VPN1_9ACTO
          Length = 449

 Score = 55.5 bits (132), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 36/140 (25%), Positives = 58/140 (41%), Gaps = 19/140 (13%)

Query: 124 ILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVE 183
           +L  V G+   S  A    G       P    +L  +     +   L   EG   P+E+ 
Sbjct: 279 VLTTVDGLLGRSGGAPATTGY----GLPLSRAALERLGCDADLTHILLSKEGM--PLELG 332

Query: 184 RLQKVYVRDPMVKAWILQQSKGICEN--CGKNAPFYLNDGNPYLEVHHVIPLSSGGADTT 241
           R +++    P ++  ++ +  G C    C K A        P+ + HH++P S+ G  + 
Sbjct: 333 RTRRIVP--PWLRRALVARDGG-CAFPQCPKPA--------PWADAHHIVPWSARGDTSL 381

Query: 242 DNCVALCPNCHRELHYSKNA 261
            N V LCP  HR LH  + A
Sbjct: 382 GNTVLLCPFHHRVLHRGEWA 401


>UniRef50_B4CXI0 HNH nuclease n=1 Tax=Chthoniobacter flavus Ellin428
           RepID=B4CXI0_9BACT
          Length = 397

 Score = 55.5 bits (132), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 25/156 (16%), Positives = 53/156 (33%), Gaps = 17/156 (10%)

Query: 130 GIYSDS-----FWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVER 184
           G+  DS     ++  +   +   + + T  +      +++L      +  G  +   +  
Sbjct: 247 GVTDDSDRKRRWFFYLEDVKPLWIGRKTRRDQRTASVMAEL---RDEEDAGELEGERMGN 303

Query: 185 LQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLS--SGGADT-T 241
                 R   +      + +  C  C  +        +  ++ HH+ PLS       T  
Sbjct: 304 TGYRLRRSGKLVLSAKMRDRFTCVACEFHYD------DQIVQAHHLDPLSERKQPEKTGL 357

Query: 242 DNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277
            + + LCPNCH   HY      + +     +  L+K
Sbjct: 358 KDLITLCPNCHYIAHYLLRKSYVYKRKDGLVAELRK 393


>UniRef50_C4V188 Putative uncharacterized protein n=1 Tax=Selenomonas flueggei ATCC
           43531 RepID=C4V188_9FIRM
          Length = 760

 Score = 55.5 bits (132), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 38/195 (19%), Positives = 72/195 (36%), Gaps = 45/195 (23%)

Query: 93  PRDIRLKMCGYQAYFSRTGRKEIPSGNRTKRILINVPGI----------------YSDSF 136
           PRD+R  +   + Y  +    +  + ++  R  ++VP I                Y D+ 
Sbjct: 569 PRDVRHIL---KYYAQKESEPKFYTFDQVDRSKLDVPAIARHIWDEDLGPKKRKEYLDAL 625

Query: 137 WASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPE--GSRKPVEVERLQ-------K 187
           W          L Q    + +  +R+  +    +S PE     + V  +++        K
Sbjct: 626 W----ESVDDNLLQLFFGKKIYFLRMVDIELAKISDPELYAPEENVTYDKIALENLPLDK 681

Query: 188 VYVRDPMVKAW--------ILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGAD 239
           +   DP ++              S  +C +CG    F       YL V H++P++ GG  
Sbjct: 682 IREIDPALEEELREGAFAKAKTSSGYVCAHCG--EVFSNRR---YLNVDHIVPMNKGGRS 736

Query: 240 TTDNCVALCPNCHRE 254
             +N   LC +C+ +
Sbjct: 737 VLENLQILCRSCNAK 751


>UniRef50_D2QPK7 Restriction endonuclease n=1 Tax=Spirosoma linguale DSM 74
           RepID=D2QPK7_9SPHI
          Length = 319

 Score = 55.5 bits (132), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 24/96 (25%), Positives = 41/96 (42%), Gaps = 3/96 (3%)

Query: 164 KLIKKTLSQPEGSRKPVE-VERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGN 222
            L    L++ E +  P++  +  +  +VR  + K  + +     C   G        DG+
Sbjct: 167 DLETYLLNEKEATYTPLQPTDDEETRFVRGGLFKKLVPKVYDFTCAISGM--KVIAVDGS 224

Query: 223 PYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258
             +E  H++P+S  G D   N +ALCPN H      
Sbjct: 225 SLVEACHIVPISVSGDDKVTNGIALCPNLHTAFDKG 260


>UniRef50_Q2SDL1 Restriction endonuclease n=2 Tax=Gammaproteobacteria
           RepID=Q2SDL1_HAHCH
          Length = 118

 Score = 55.1 bits (131), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 17/61 (27%), Positives = 27/61 (44%), Gaps = 5/61 (8%)

Query: 193 PMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252
             ++A IL++   +C+ C K             +V H+ P + GG D   N  A+C  CH
Sbjct: 57  RKLRARILRRDNYLCQVCLKQGRTSAAT-----QVDHIQPKAQGGDDQVGNLQAICRLCH 111

Query: 253 R 253
            
Sbjct: 112 S 112


>UniRef50_Q892G5 Phage-related protein n=1 Tax=Clostridium tetani RepID=Q892G5_CLOTE
          Length = 142

 Score = 55.1 bits (131), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 24/137 (17%), Positives = 55/137 (40%), Gaps = 14/137 (10%)

Query: 143 GELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQ 202
           G++ + +Q   ++           +    +     K  +   + K +    +++  + Q+
Sbjct: 9   GKVLDYTQKYCNDCSKKFEEQNRERYRHYKKNRKDKKEQRFYVSKEWT---IIRDTVKQR 65

Query: 203 SKGICENCGKNAPFYLNDGNPYLE-VHHVIPLSS--GGADTTDNCVALCPNCHRELH--Y 257
            +G+C+ C             Y++ VHH+  L           N ++LC +CH+++H  Y
Sbjct: 66  DRGLCKLC------LSKCNITYMDTVHHIEELKDCWDKRLDPGNLISLCESCHQKVHEEY 119

Query: 258 SKNAKELIEMLYVNINR 274
             N  ++ + L   I R
Sbjct: 120 KNNKLDIQKELEKLIER 136


>UniRef50_B2JEA1 Restriction endonuclease-like protein n=1 Tax=Burkholderia phymatum
           STM815 RepID=B2JEA1_BURP8
          Length = 431

 Score = 55.1 bits (131), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 23/116 (19%), Positives = 40/116 (34%), Gaps = 7/116 (6%)

Query: 150 QPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSK-GICE 208
           Q        N   S++      +    +    ++R +   + +     +         CE
Sbjct: 308 QVVKKGETYNAPDSEISIDREWREGDIKLRSHLKRERAPGLANAKKAQYRQAHDGRLTCE 367

Query: 209 NCGKN--APFYLNDGNPYLEVHH----VIPLSSGGADTTDNCVALCPNCHRELHYS 258
            CG +    +   D    +EVHH    V  + +G     D+   LC NCHR +H  
Sbjct: 368 LCGLDPVERYKTKDAEACIEVHHSAVHVSEMPTGHKTALDDLQCLCANCHRLIHKK 423


>UniRef50_A6XRX8 Putative uncharacterized protein n=1 Tax=Vibrio cholerae AM-19226
           RepID=A6XRX8_VIBCH
          Length = 243

 Score = 55.1 bits (131), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 7/64 (10%)

Query: 192 DPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNC 251
              VK   +  S   C  C K   F        +E+HH+ P + GGADT  N + LC +C
Sbjct: 4   SLKVKEDAMVASGRHCCLCHK---FCGLK----IEIHHIKPRADGGADTFQNAIPLCFDC 56

Query: 252 HREL 255
           H ++
Sbjct: 57  HADM 60


>UniRef50_A6TQ34 Putative uncharacterized protein n=3 Tax=Firmicutes
           RepID=A6TQ34_ALKMQ
          Length = 290

 Score = 55.1 bits (131), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 22/80 (27%), Positives = 32/80 (40%), Gaps = 2/80 (2%)

Query: 191 RDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPN 250
           RDP  +  IL+  +  C  CG N    L +    +E  H+    +GG D  +N +ALC  
Sbjct: 159 RDPKFREKILRAYEYKCAVCGFN--VRLGNNLIAVEAAHIKWHQAGGPDNENNGMALCVM 216

Query: 251 CHRELHYSKNAKELIEMLYV 270
            H+              L V
Sbjct: 217 HHKLFDRGVFTLTSSRKLLV 236


>UniRef50_C1YI89 Predicted restriction endonuclease n=2 Tax=Actinomycetales
           RepID=C1YI89_NOCDA
          Length = 290

 Score = 55.1 bits (131), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 19/69 (27%), Positives = 25/69 (36%), Gaps = 2/69 (2%)

Query: 190 VRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCP 249
           VRDP  +  +L   +  C  CG             LE  H+   S  G +  DN + LCP
Sbjct: 162 VRDPRFRETVLTAYEHRCAFCGYEGRLDGVSVG--LEAAHIRWWSYDGPNDLDNGLCLCP 219

Query: 250 NCHRELHYS 258
             H      
Sbjct: 220 THHLLFDRG 228


>UniRef50_Q7M1J5 Reverse transcription like protein 2, intron-encoded (Fragment) n=1
           Tax=Pylaiella littoralis RepID=Q7M1J5_PYLLI
          Length = 308

 Score = 55.1 bits (131), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 21/71 (29%), Positives = 34/71 (47%), Gaps = 6/71 (8%)

Query: 191 RDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPN 250
           RD     +  ++ K  C+ C +        G   +E+HH+ P S GG D   N V L   
Sbjct: 244 RDLAKLYYT-RRDKYKCKVCNEYI-----CGEDKVEIHHIKPKSLGGDDAISNNVVLHAE 297

Query: 251 CHRELHYSKNA 261
           CH++L ++K+ 
Sbjct: 298 CHKQLTHTKSR 308


>UniRef50_UPI0001AEF119 restriction endonuclease n=1 Tax=Streptomyces ghanaensis ATCC 14672
           RepID=UPI0001AEF119
          Length = 572

 Score = 55.1 bits (131), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 22/85 (25%), Positives = 32/85 (37%), Gaps = 6/85 (7%)

Query: 171 SQPEGSRKPVEVERLQ-KVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHH 229
            + E    PV    +     VRDP +   + +     C+ CG     + +    Y E  H
Sbjct: 438 EEQETEPGPVSRRTVTLSRIVRDPELTTMVKRLHGDRCQVCGLQLSTHFST---YSEAAH 494

Query: 230 VIPLSS--GGADTTDNCVALCPNCH 252
           +  L     G D   N + LCPN H
Sbjct: 495 IRGLGRPHNGPDKLSNLLVLCPNHH 519


Searching..................................................done


Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_P24200 5-methylcytosine-specific restriction enzyme A n...   383   e-105
UniRef50_C0QGN0 Putative 5-methylcytosine-specific restriction e...   182   1e-44
UniRef50_UPI00016A2859 HNH endonuclease n=1 Tax=Burkholderia tha...   144   3e-33
UniRef50_A9BU78 HNH endonuclease n=4 Tax=Burkholderiales RepID=A...   142   2e-32
UniRef50_Q2Y8M1 HNH nuclease n=1 Tax=Nitrosospira multiformis AT...   139   1e-31
UniRef50_C3K0B7 Putative 5-methylcytosine-specific restriction e...   137   4e-31
UniRef50_A0KIQ7 Probable 5-methylcytosine-specific restriction e...   134   4e-30
UniRef50_A6QD09 5-methylcytosine-specific restriction enzyme A n...   132   1e-29
UniRef50_Q1YK78 Putative 5-methylcytosine-specific restriction e...   128   2e-28
UniRef50_Q080H4 HNH endonuclease n=1 Tax=Shewanella frigidimarin...   124   3e-27
UniRef50_B5EI94 HNH endonuclease n=1 Tax=Geobacter bemidjiensis ...   121   2e-26
UniRef50_A8ZWC1 HNH endonuclease n=1 Tax=Desulfococcus oleovoran...   121   3e-26
UniRef50_Q3K870 Putative 5-methylcytosine-specific restriction e...   118   2e-25
UniRef50_C4WNE8 Putative uncharacterized protein n=1 Tax=Ochroba...   118   2e-25
UniRef50_C7HJ98 HNH endonuclease n=1 Tax=Clostridium thermocellu...   117   4e-25
UniRef50_D0Z3H8 HNH nuclease n=1 Tax=Photobacterium damselae sub...   116   1e-24
UniRef50_C3FAM5 HNH nuclease n=4 Tax=Bacillus cereus group RepID...   114   3e-24
UniRef50_Q312Y0 HNH nuclease n=1 Tax=Desulfovibrio desulfuricans...   114   3e-24
UniRef50_C4SUH5 Restriction endonuclease n=1 Tax=Yersinia freder...   114   4e-24
UniRef50_A2SMM5 Putative uncharacterized protein n=1 Tax=Methyli...   114   5e-24
UniRef50_A3JQK6 HNH nuclease n=1 Tax=Rhodobacterales bacterium H...   114   5e-24
UniRef50_C3LV13 HNH endonuclease n=13 Tax=Vibrio RepID=C3LV13_VIBCM   113   5e-24
UniRef50_D0KA86 HNH endonuclease n=2 Tax=Enterobacteriaceae RepI...   113   6e-24
UniRef50_C6ANH6 HNH nuclease n=1 Tax=Aggregatibacter aphrophilus...   107   3e-22
UniRef50_C0WRI9 Possible HNH endonuclease n=1 Tax=Lactobacillus ...   107   3e-22
UniRef50_A4SC99 HNH endonuclease n=1 Tax=Chlorobium phaeovibrioi...   106   7e-22
UniRef50_C0ZFI2 Putative uncharacterized protein n=1 Tax=Breviba...   106   1e-21
UniRef50_C0N619 HNH endonuclease domain protein n=1 Tax=Methylop...   105   2e-21
UniRef50_C8U495 Endonuclease-like protein n=2 Tax=Escherichia co...   105   2e-21
UniRef50_D2C2V7 HNH endonuclease n=1 Tax=Dickeya dadantii Ech586...   105   2e-21
UniRef50_C9PPM2 5-methylcytosine-specific restriction enzyme A n...   104   3e-21
UniRef50_Q8TKB6 Hnh endonuclease n=2 Tax=Methanosarcina RepID=Q8...   104   3e-21
UniRef50_B1ZSH9 Restriction endonuclease-like protein n=1 Tax=Op...   104   5e-21
UniRef50_Q60BH4 Putative uncharacterized protein n=1 Tax=Methylo...   104   5e-21
UniRef50_C9XQW3 Putative uncharacterized protein n=2 Tax=Clostri...   103   6e-21
UniRef50_C2KXT9 Putative uncharacterized protein n=1 Tax=Oribact...   103   6e-21
UniRef50_A0L1U4 HNH endonuclease n=1 Tax=Shewanella sp. ANA-3 Re...   103   6e-21
UniRef50_Q9L0M9 Putative uncharacterized protein SCO4631 n=3 Tax...   103   8e-21
UniRef50_A9AZQ2 HNH endonuclease n=1 Tax=Herpetosiphon aurantiac...   102   1e-20
UniRef50_Q0BZ66 Conserved domain protein n=1 Tax=Hyphomonas nept...   102   1e-20
UniRef50_C3RB64 Predicted protein n=1 Tax=Bacteroides dorei 5_1_...   102   2e-20
UniRef50_C4L1L5 HNH endonuclease n=2 Tax=Bacillales RepID=C4L1L5...   101   2e-20
UniRef50_Q0F8W7 Putative uncharacterized protein n=1 Tax=Rhodoba...   101   2e-20
UniRef50_C5RG47 HNH endonuclease n=1 Tax=Clostridium cellulovora...   101   2e-20
UniRef50_B4S2Y7 HNH nuclease n=2 Tax=Proteobacteria RepID=B4S2Y7...   101   3e-20
UniRef50_B3EB35 HNH endonuclease n=1 Tax=Geobacter lovleyi SZ Re...   101   3e-20
UniRef50_A6VSV6 HNH endonuclease n=1 Tax=Marinomonas sp. MWYL1 R...   101   3e-20
UniRef50_C6MKA5 HNH endonuclease n=1 Tax=Geobacter sp. M18 RepID...   100   1e-19
UniRef50_UPI0001BC350E HNH endonuclease n=1 Tax=Butyrivibrio cro...   100   1e-19
UniRef50_A0YCZ6 Putative uncharacterized protein n=1 Tax=marine ...    99   1e-19
UniRef50_C3G8U4 HNH endonuclease n=1 Tax=Bacillus thuringiensis ...    99   1e-19
UniRef50_B5G9G0 HNH endonuclease n=1 Tax=Streptomyces sp. SPB74 ...    99   2e-19
UniRef50_UPI0001BC7B91 HNH endonuclease n=1 Tax=Bacteroides sp. ...    99   2e-19
UniRef50_C3C627 Restriction endonuclease n=7 Tax=Bacillus RepID=...    99   2e-19
UniRef50_C1SP87 Predicted restriction endonuclease n=1 Tax=Denit...    98   2e-19
UniRef50_C3IFK0 5-methylcytosine-specific restriction enzyme A n...    98   3e-19
UniRef50_B1QVB2 HNH endonuclease domain protein n=2 Tax=Clostrid...    98   3e-19
UniRef50_D2QLF4 HNH endonuclease n=1 Tax=Spirosoma linguale DSM ...    98   3e-19
UniRef50_A9F818 Putative restriction endonuclease n=1 Tax=Phaeob...    98   4e-19
UniRef50_Q1L9I8 HNH nuclease n=2 Tax=cellular organisms RepID=Q1...    97   5e-19
UniRef50_C9ADX3 5-methylcytosine-specific restriction enzyme A n...    97   5e-19
UniRef50_UPI0001A457FB putative 5-methylcytosine-specific restri...    97   6e-19
UniRef50_B1ZMM6 HNH endonuclease n=1 Tax=Opitutus terrae PB90-1 ...    96   9e-19
UniRef50_B3CDE4 Putative uncharacterized protein n=1 Tax=Bactero...    96   9e-19
UniRef50_Q1QEV2 HNH endonuclease n=5 Tax=Gammaproteobacteria Rep...    96   9e-19
UniRef50_A9B4I7 HNH endonuclease n=1 Tax=Herpetosiphon aurantiac...    96   1e-18
UniRef50_B9DID5 Putative uncharacterized protein n=1 Tax=Staphyl...    96   1e-18
UniRef50_Q67M53 Conserved domain protein n=1 Tax=Symbiobacterium...    96   1e-18
UniRef50_C4UQ38 Putative uncharacterized protein n=1 Tax=Yersini...    96   1e-18
UniRef50_Q0AUW7 Hnh endonuclease n=1 Tax=Syntrophomonas wolfei s...    96   2e-18
UniRef50_D1NJY2 Transcriptional regulator, XRE family n=1 Tax=Cl...    95   2e-18
UniRef50_D1P9G2 5-methylcytosine-specific restriction enzyme A n...    95   2e-18
UniRef50_C8TQ55 Predicted endonuclease n=10 Tax=Enterobacteriace...    95   2e-18
UniRef50_Q8VUW2 Putative uncharacterized protein 5'-methylcytosi...    95   3e-18
UniRef50_A5W5D0 HNH endonuclease n=4 Tax=Gammaproteobacteria Rep...    94   3e-18
UniRef50_B0KIU7 HNH endonuclease n=1 Tax=Pseudomonas putida GB-1...    94   3e-18
UniRef50_C9BZK6 Restriction endonuclease (Fragment) n=4 Tax=Firm...    94   3e-18
UniRef50_D2S1X8 HNH endonuclease n=1 Tax=Haloterrigena turkmenic...    94   5e-18
UniRef50_B0KGB9 Restriction endonuclease-like protein n=1 Tax=Ps...    94   6e-18
UniRef50_C6J8S5 Putative uncharacterized protein n=1 Tax=Ruminoc...    93   8e-18
UniRef50_B0A7V0 Putative uncharacterized protein n=1 Tax=Clostri...    93   8e-18
UniRef50_C6LDW0 Product McrA n=1 Tax=Bryantella formatexigens DS...    93   8e-18
UniRef50_A9GYN9 Putative uncharacterized protein n=1 Tax=Roseoba...    93   8e-18
UniRef50_A7I926 HNH endonuclease n=1 Tax=Candidatus Methanoregul...    93   9e-18
UniRef50_A0KZG4 HNH endonuclease n=1 Tax=Shewanella sp. ANA-3 Re...    93   1e-17
UniRef50_D0IIJ2 HNH endonuclease n=1 Tax=Vibrio sp. RC586 RepID=...    93   1e-17
UniRef50_D1BJK4 HNH endonuclease n=1 Tax=Sanguibacter keddieii D...    93   1e-17
UniRef50_B8KVR3 HNH endonuclease domain protein n=1 Tax=gamma pr...    92   2e-17
UniRef50_C0CT91 Putative uncharacterized protein n=1 Tax=Clostri...    92   2e-17
UniRef50_A0JWW4 HNH endonuclease n=1 Tax=Arthrobacter sp. FB24 R...    92   2e-17
UniRef50_O83027 Disrupted by IS8301 insertion n=1 Tax=Deinococcu...    92   2e-17
UniRef50_A3WCW2 HNH endonuclease n=1 Tax=Erythrobacter sp. NAP1 ...    92   2e-17
UniRef50_D2YGR3 Putative uncharacterized protein n=1 Tax=Vibrio ...    92   2e-17
UniRef50_A3U4A6 E14 prophage-like protein n=1 Tax=Oceanicola bat...    91   4e-17
UniRef50_D2YH85 Putative uncharacterized protein n=1 Tax=Vibrio ...    91   5e-17
UniRef50_B2IKM5 HNH endonuclease n=1 Tax=Beijerinckia indica sub...    91   5e-17
UniRef50_Q1YWU8 Putative uncharacterized protein n=3 Tax=Gammapr...    90   7e-17
UniRef50_Q6EME6 Hnh endonuclease n=6 Tax=Enterobacteriaceae RepI...    90   8e-17
UniRef50_C8S4R5 HNH endonuclease n=1 Tax=Rhodobacter sp. SW2 Rep...    90   1e-16
UniRef50_A8R8M0 Putative uncharacterized protein n=1 Tax=Eubacte...    90   1e-16
UniRef50_Q0KFQ5 Predicted restriction endonuclease n=1 Tax=Ralst...    90   1e-16
UniRef50_Q64YP3 Putative uncharacterized protein n=1 Tax=Bactero...    89   2e-16
UniRef50_Q3K789 Putative HNH endonuclease n=1 Tax=Pseudomonas fl...    89   2e-16
UniRef50_C3AW04 Putative uncharacterized protein n=1 Tax=Bacillu...    89   2e-16
UniRef50_A6GA77 HNH endonuclease n=1 Tax=Plesiocystis pacifica S...    88   3e-16
UniRef50_C4F8E8 Putative uncharacterized protein n=1 Tax=Collins...    88   3e-16
UniRef50_Q5L3M3 Hnh endonuclease n=1 Tax=Geobacillus kaustophilu...    88   3e-16
UniRef50_C2ECC9 Recombinase n=1 Tax=Lactobacillus ruminis ATCC 2...    88   5e-16
UniRef50_A0YK66 Putative uncharacterized protein n=1 Tax=Lyngbya...    87   5e-16
UniRef50_C5QAR7 HNH endonuclease n=5 Tax=Firmicutes RepID=C5QAR7...    87   6e-16
UniRef50_A5ELB4 Putative uncharacterized protein n=1 Tax=Bradyrh...    87   6e-16
UniRef50_D1XF45 HNH endonuclease n=3 Tax=Streptomyces RepID=D1XF...    87   8e-16
UniRef50_Q0HF94 Putative uncharacterized protein n=1 Tax=Shewane...    86   1e-15
UniRef50_B1I905 HNH endonuclease domain protein n=3 Tax=Streptoc...    86   1e-15
UniRef50_A3US95 Putative restriction endonuclease n=1 Tax=Vibrio...    86   1e-15
UniRef50_Q4K9Y7 Putative uncharacterized protein n=1 Tax=Pseudom...    86   1e-15
UniRef50_Q5YRW6 Putative endonuclease n=1 Tax=Nocardia farcinica...    85   2e-15
UniRef50_A1F1U9 HNH endonuclease domain protein n=1 Tax=Vibrio c...    85   2e-15
UniRef50_D0S0J8 Hnh endonuclease n=1 Tax=Acinetobacter calcoacet...    85   3e-15
UniRef50_C3L8D2 Putative uncharacterized protein n=6 Tax=Bacillu...    85   3e-15
UniRef50_C2NAK2 HNH endonuclease n=1 Tax=Bacillus cereus ATCC 10...    84   4e-15
UniRef50_A7C7H9 HNH endonuclease n=2 Tax=Gammaproteobacteria Rep...    84   4e-15
UniRef50_A9VH89 HNH endonuclease n=3 Tax=Bacillus cereus group R...    84   4e-15
UniRef50_B0ACA5 Putative uncharacterized protein n=1 Tax=Clostri...    84   5e-15
UniRef50_Q8YJX6 All8554 protein n=2 Tax=Cyanobacteria RepID=Q8YJ...    84   5e-15
UniRef50_B5ERY9 Restriction endonuclease-like protein n=1 Tax=Ac...    84   6e-15
UniRef50_Q477P3 HNH endonuclease n=1 Tax=Ralstonia eutropha JMP1...    84   6e-15
UniRef50_C4ZAA3 Putative uncharacterized protein n=1 Tax=Eubacte...    83   7e-15
UniRef50_UPI0001BC7063 hypothetical protein VparAQ_18636 n=1 Tax...    83   1e-14
UniRef50_Q984I3 Mll7993 protein n=1 Tax=Mesorhizobium loti RepID...    83   1e-14
UniRef50_UPI0001B4E4C9 hypothetical protein ShygA5_17857 n=2 Tax...    83   1e-14
UniRef50_C4L074 HNH endonuclease n=1 Tax=Exiguobacterium sp. AT1...    83   2e-14
UniRef50_C5ZWY1 Putative uncharacterized protein n=1 Tax=Helicob...    83   2e-14
UniRef50_A9B5H7 HNH endonuclease n=1 Tax=Herpetosiphon aurantiac...    82   2e-14
UniRef50_B7JSJ9 DNA helicase, putative n=1 Tax=Bacillus cereus A...    82   2e-14
UniRef50_B1KV86 Hnh endonuclease n=5 Tax=Firmicutes RepID=B1KV86...    82   2e-14
UniRef50_B8FFI4 HNH endonuclease n=1 Tax=Desulfatibacillum alken...    81   3e-14
UniRef50_Q6LSI1 Putative uncharacterized protein MLL7993 n=1 Tax...    81   3e-14
UniRef50_B4SDY4 HNH nuclease n=4 Tax=Bacteria RepID=B4SDY4_PELPB       81   4e-14
UniRef50_C4V188 Putative uncharacterized protein n=1 Tax=Selenom...    81   4e-14
UniRef50_UPI0000E87DB3 hypothetical protein MB2181_05395 n=1 Tax...    81   4e-14
UniRef50_D2AT16 Putative uncharacterized protein n=1 Tax=Strepto...    81   4e-14
UniRef50_Q65MN2 McrA n=2 Tax=Bacillus subtilis group RepID=Q65MN...    81   4e-14
UniRef50_Q2FQI6 HNH endonuclease n=1 Tax=Methanospirillum hungat...    81   4e-14
UniRef50_D2S2Y4 HNH endonuclease n=1 Tax=Haloterrigena turkmenic...    81   5e-14
UniRef50_UPI000197A09F restriction endonuclease n=1 Tax=Helicoba...    81   5e-14
UniRef50_A5UU02 HNH endonuclease n=16 Tax=Bacteria RepID=A5UU02_...    81   5e-14
UniRef50_Q6NKI3 Putative uncharacterized protein n=1 Tax=Coryneb...    81   6e-14
UniRef50_A4G659 Putative restriction endonuclease n=1 Tax=Hermin...    81   6e-14
UniRef50_D0WS63 Putative uncharacterized protein n=1 Tax=Vibrio ...    81   6e-14
UniRef50_B1QVB3 HNH endonuclease domain protein n=2 Tax=Clostrid...    80   6e-14
UniRef50_Q46AN8 Putative uncharacterized protein n=1 Tax=Methano...    80   6e-14
UniRef50_C7NQZ2 HNH endonuclease n=1 Tax=Halorhabdus utahensis D...    80   6e-14
UniRef50_Q723Z7 Conserved domain protein n=4 Tax=Listeria monocy...    80   6e-14
UniRef50_C7V3C1 Predicted protein n=1 Tax=Enterococcus faecalis ...    80   8e-14
UniRef50_D2QLF7 HNH endonuclease n=1 Tax=Spirosoma linguale DSM ...    80   9e-14
UniRef50_Q3A7T9 Predicted restriction endonuclease n=6 Tax=Delta...    80   9e-14
UniRef50_D0LYP9 HNH endonuclease n=1 Tax=Haliangium ochraceum DS...    80   1e-13
UniRef50_B0TQV8 Restriction endonuclease-like protein n=1 Tax=Sh...    79   1e-13
UniRef50_C3GU40 HNH endonuclease n=2 Tax=Bacillus thuringiensis ...    79   1e-13
UniRef50_B9LX84 HNH endonuclease n=1 Tax=Halorubrum lacusprofund...    79   1e-13
UniRef50_UPI0001BCB4D2 hypothetical protein VparK_03069 n=1 Tax=...    79   1e-13
UniRef50_C3IFK4 5-methylcytosine-specific restriction enzyme A n...    79   1e-13
UniRef50_Q3EYN0 HNH endonuclease family protein n=1 Tax=Bacillus...    79   2e-13
UniRef50_B8F0E2 Restriction endonuclease-like protein n=1 Tax=Th...    79   2e-13
UniRef50_A3WFM1 5-methylcytosine-specific restriction enzyme A n...    79   2e-13
UniRef50_Q6NMJ9 At2g23840 n=6 Tax=Magnoliophyta RepID=Q6NMJ9_ARATH     79   2e-13
UniRef50_B7A588 HNH endonuclease n=1 Tax=Thermus aquaticus Y51MC...    79   2e-13
UniRef50_Q82RB7 Putative reverse transcriptase homolog; similar ...    79   2e-13
UniRef50_Q2S547 Putative uncharacterized protein n=1 Tax=Salinib...    79   2e-13
UniRef50_C1YI89 Predicted restriction endonuclease n=2 Tax=Actin...    78   2e-13
UniRef50_Q2FRM5 HNH endonuclease n=1 Tax=Methanospirillum hungat...    78   3e-13
UniRef50_C1V6S3 HNH endonuclease n=1 Tax=Halogeometricum borinqu...    78   3e-13
UniRef50_B7UQU7 Predicted restriction endonuclease n=81 Tax=Gamm...    78   3e-13
UniRef50_C6WXV3 HNH endonuclease n=3 Tax=Proteobacteria RepID=C6...    78   4e-13
UniRef50_B4D4V1 HNH endonuclease n=1 Tax=Chthoniobacter flavus E...    78   4e-13
UniRef50_A3HSL8 Putative uncharacterized protein n=1 Tax=Algorip...    77   5e-13
UniRef50_B0N4T9 Putative uncharacterized protein n=1 Tax=Clostri...    77   5e-13
UniRef50_D2RPV1 Restriction endonuclease-like protein n=1 Tax=Ha...    77   6e-13
UniRef50_C4XM37 Putative uncharacterized protein n=1 Tax=Desulfo...    77   7e-13
UniRef50_A9AVZ1 HNH nuclease n=1 Tax=Herpetosiphon aurantiacus A...    77   7e-13
UniRef50_C0GPK5 Restriction endonuclease n=1 Tax=Desulfonatronos...    77   8e-13
UniRef50_B8JBJ0 HNH endonuclease n=4 Tax=Anaeromyxobacter dehalo...    77   8e-13
UniRef50_Q7UQV2 Restriction endonuclease n=1 Tax=Rhodopirellula ...    76   1e-12
UniRef50_A5V9C7 HNH endonuclease n=1 Tax=Sphingomonas wittichii ...    76   1e-12
UniRef50_C4K5N9 Group II intron encoded reverse transcriptase n=...    76   1e-12
UniRef50_Q0RLC9 Putative uncharacterized protein n=1 Tax=Frankia...    76   1e-12
UniRef50_C3XKK9 Restriction endonuclease n=1 Tax=Helicobacter wi...    76   1e-12
UniRef50_Q3EQP7 5-methylcytosine-specific restriction enzyme A n...    76   1e-12
UniRef50_A1B3Q8 HNH endonuclease n=2 Tax=Rhodobacteraceae RepID=...    76   1e-12
UniRef50_Q81E47 5-methylcytosine-specific restriction enzyme A n...    76   1e-12
UniRef50_B9JB56 Putative uncharacterized protein n=1 Tax=Agrobac...    76   2e-12
UniRef50_D0C4R2 HNH endonuclease n=1 Tax=Acinetobacter sp. RUH26...    76   2e-12
UniRef50_Q8DK67 Reverse transcriptase n=1 Tax=Thermosynechococcu...    75   2e-12
UniRef50_B1XNN9 Restriction endonuclease n=20 Tax=Cyanobacteria ...    75   2e-12
UniRef50_B9ZDV6 HNH endonuclease n=1 Tax=Natrialba magadii ATCC ...    75   2e-12
UniRef50_D1VPN1 HNH endonuclease n=1 Tax=Frankia sp. EuI1c RepID...    75   3e-12
UniRef50_A3UIJ5 Putative uncharacterized protein n=1 Tax=Oceanic...    75   3e-12
UniRef50_A6FN65 HIT family protein n=5 Tax=root RepID=A6FN65_9RHOB     75   3e-12
UniRef50_C7LPI3 Restriction endonuclease n=1 Tax=Desulfomicrobiu...    75   3e-12
UniRef50_UPI0001C311B3 HNH endonuclease n=1 Tax=Conexibacter woe...    75   3e-12
UniRef50_C5VAT3 HNH endonuclease n=3 Tax=Corynebacterium RepID=C...    75   3e-12
UniRef50_B4CXI0 HNH nuclease n=1 Tax=Chthoniobacter flavus Ellin...    75   3e-12
UniRef50_D2MHK7 HNH endonuclease n=3 Tax=Bacteria RepID=D2MHK7_9...    74   3e-12
UniRef50_C7D6X3 Putative uncharacterized protein n=1 Tax=Thalass...    74   3e-12
UniRef50_Q2IJQ6 HNH endonuclease n=1 Tax=Anaeromyxobacter dehalo...    74   4e-12
UniRef50_Q8YYJ2 Alr0856 protein n=6 Tax=Cyanobacteria RepID=Q8YY...    74   4e-12
UniRef50_B4SCA5 HNH nuclease n=1 Tax=Pelodictyon phaeoclathratif...    74   4e-12
UniRef50_D1S1E3 HNH nuclease n=1 Tax=Micromonospora aurantiaca A...    74   5e-12
UniRef50_Q3IBU7 Putative HNH endonuclease n=1 Tax=Pseudoalteromo...    74   5e-12
UniRef50_C6WMA3 HNH nuclease n=1 Tax=Actinosynnema mirum DSM 438...    74   5e-12
UniRef50_C9RCK5 HNH endonuclease n=2 Tax=Ammonifex degensii KC4 ...    74   5e-12
UniRef50_Q2IGI7 HNH nuclease n=29 Tax=Anaeromyxobacter RepID=Q2I...    74   6e-12
UniRef50_D2R238 HNH endonuclease n=4 Tax=Planctomycetaceae RepID...    74   6e-12
UniRef50_D2R9B6 HNH endonuclease n=1 Tax=Pirellula staleyi DSM 6...    74   6e-12
UniRef50_C9RBS6 HNH endonuclease n=4 Tax=Ammonifex degensii KC4 ...    74   7e-12
UniRef50_B9I5Z1 Predicted protein n=7 Tax=Magnoliophyta RepID=B9...    74   7e-12
UniRef50_C3BJL8 Paclitaxel/taxanoid biosynthesis susceptibility ...    73   8e-12
UniRef50_A9FIM4 HNH endonuclease family protein n=1 Tax=Sorangiu...    73   8e-12
UniRef50_Q8YML8 Alr4915 protein n=2 Tax=Nostocaceae RepID=Q8YML8...    73   1e-11
UniRef50_B4UMG8 HNH endonuclease n=3 Tax=Anaeromyxobacter RepID=...    73   1e-11
UniRef50_B0PAM8 Putative uncharacterized protein n=1 Tax=Anaerot...    73   1e-11
UniRef50_A8H4Z7 HNH nuclease n=1 Tax=Shewanella pealeana ATCC 70...    73   1e-11
UniRef50_Q82CY5 Putative uncharacterized protein n=1 Tax=Strepto...    73   1e-11
UniRef50_B9PFL0 Predicted protein (Fragment) n=2 Tax=cellular or...    73   1e-11
UniRef50_A6TQ34 Putative uncharacterized protein n=3 Tax=Firmicu...    73   1e-11
UniRef50_Q82H00 Putative uncharacterized protein n=1 Tax=Strepto...    73   1e-11
UniRef50_B0MB74 Putative uncharacterized protein n=1 Tax=Anaeros...    73   1e-11
UniRef50_A8L869 Restriction endonuclease-like protein n=2 Tax=Ac...    73   1e-11
UniRef50_B4U6J4 HNH endonuclease n=1 Tax=Hydrogenobaculum sp. Y0...    73   1e-11
UniRef50_C3JTD3 HNH endonuclease (Fragment) n=3 Tax=Rhodococcus ...    73   1e-11
UniRef50_Q3ISZ2 Putative uncharacterized protein n=1 Tax=Natrono...    73   1e-11
UniRef50_C8WWQ2 HNH endonuclease n=27 Tax=Bacteria RepID=C8WWQ2_...    73   1e-11
UniRef50_A1ZG09 Paclitaxel/taxanoid biosynthesis susceptibility ...    73   1e-11
UniRef50_Q306Z6 HNH endonuclease (Fragment) n=1 Tax=Arthrospira ...    73   2e-11
UniRef50_Q538B5 MnlI restriction endonuclease n=2 Tax=Moraxella ...    72   2e-11
UniRef50_D0UZ69 PCQ3_20 n=1 Tax=Streptomyces sp. W9 RepID=D0UZ69...    72   2e-11
UniRef50_A0PZM8 HNH endonuclease domain protein n=3 Tax=Bacteria...    72   2e-11
UniRef50_A3PZ99 Putative uncharacterized protein n=14 Tax=Mycoba...    72   2e-11
UniRef50_A3Z7E0 HIT family protein n=6 Tax=Synechococcus RepID=A...    72   2e-11
UniRef50_B0JFS6 HNH endonuclease n=2 Tax=Cyanobacteria RepID=B0J...    72   2e-11
UniRef50_Q73WH9 Putative uncharacterized protein n=1 Tax=Mycobac...    72   2e-11
UniRef50_B3EKH2 HNH endonuclease n=10 Tax=Chlorobiaceae RepID=B3...    72   2e-11
UniRef50_A4EXC6 Putative uncharacterized protein n=3 Tax=Rhodoba...    72   2e-11
UniRef50_C0XUG8 HNH endonuclease n=1 Tax=Corynebacterium lipophi...    72   2e-11
UniRef50_C7Q4G6 HNH endonuclease n=1 Tax=Catenulispora acidiphil...    72   2e-11
UniRef50_B6AYM6 Restriction endonuclease n=2 Tax=Rhodobacterales...    72   3e-11
UniRef50_A0ZAT3 Putative uncharacterized protein n=1 Tax=Nodular...    72   3e-11
UniRef50_Q21AN9 HNH endonuclease n=1 Tax=Rhodopseudomonas palust...    72   3e-11
UniRef50_A2SMN0 Putative uncharacterized protein n=1 Tax=Methyli...    71   3e-11

Sequences not found previously or not previously below threshold:

>UniRef50_P24200 5-methylcytosine-specific restriction enzyme A n=2 Tax=Escherichia
           coli RepID=MCRA_ECOLI
          Length = 277

 Score =  383 bits (982), Expect = e-105,   Method: Composition-based stats.
 Identities = 277/277 (100%), Positives = 277/277 (100%)

Query: 1   MHVFDNNGIELKAECSIGEEDGVYGLILESWGPGDRNKDYNIALDYIIERLVDSGVSQVV 60
           MHVFDNNGIELKAECSIGEEDGVYGLILESWGPGDRNKDYNIALDYIIERLVDSGVSQVV
Sbjct: 1   MHVFDNNGIELKAECSIGEEDGVYGLILESWGPGDRNKDYNIALDYIIERLVDSGVSQVV 60

Query: 61  VYLASSSVRKHMHSLDERKIHPGEYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEIPSGNR 120
           VYLASSSVRKHMHSLDERKIHPGEYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEIPSGNR
Sbjct: 61  VYLASSSVRKHMHSLDERKIHPGEYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEIPSGNR 120

Query: 121 TKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPV 180
           TKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPV
Sbjct: 121 TKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPV 180

Query: 181 EVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADT 240
           EVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADT
Sbjct: 181 EVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADT 240

Query: 241 TDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277
           TDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK
Sbjct: 241 TDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277


>UniRef50_C0QGN0 Putative 5-methylcytosine-specific restriction enzyme A n=1
           Tax=Desulfobacterium autotrophicum HRM2
           RepID=C0QGN0_DESAH
          Length = 375

 Score =  182 bits (461), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 54/258 (20%), Positives = 104/258 (40%), Gaps = 25/258 (9%)

Query: 22  GVYGLILESWGPGDRNKDYNIALDYIIERLVDSGVSQVVVYLASSSVRKHMHSLDERKIH 81
           G YG+  ES      + D    +  + E+    G+ +++ +  +    +H+ S +  +  
Sbjct: 137 GGYGVSQESKWSKVNDDDLVYVIQNVYEKFEFCGIYRILSHYKN----EHIGSKNHFRFQ 192

Query: 82  PGEYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEIPSG-NRTKRILINVPGIYSDSFWASI 140
             +   LI  +P DI   +CG      R  + E P+  +  KR   +    + +   + +
Sbjct: 193 LEDITCLI--NPIDINEDLCG-----RRLPQLEKPANWSNFKRHFCSQGATFRNPLSSEV 245

Query: 141 IRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWIL 200
            +     L     D+            + +   EG+++ V + +    Y RD   +   +
Sbjct: 246 FQV----LDSLLPDKRPFQFAEEISENEEMLFFEGAKQTVTINK----YERDHNARKACI 297

Query: 201 QQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSSGGA----DTTDNCVALCPNCHREL 255
           +     C+ CG +    Y   G  Y+ VHH+IPLS  G     +   + + +CPNCH  L
Sbjct: 298 EYHGYNCKVCGFDFEKTYGELGRNYIHVHHLIPLSKIGKEYSINPQTDLIPVCPNCHAML 357

Query: 256 HYSKNAKELIEMLYVNIN 273
           H S+N  +L  +  +   
Sbjct: 358 HKSENPNDLYSLKKMIQK 375


>UniRef50_UPI00016A2859 HNH endonuclease n=1 Tax=Burkholderia thailandensis TXDOH
           RepID=UPI00016A2859
          Length = 214

 Score =  144 bits (362), Expect = 3e-33,   Method: Composition-based stats.
 Identities = 61/194 (31%), Positives = 94/194 (48%), Gaps = 9/194 (4%)

Query: 84  EYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRG 143
           +    IG S +    +M          GR  IP       + + V G           R 
Sbjct: 29  DLAAQIGRSEKSCEYRMRNISYVLELMGRDWIPGLPPATNVGVRVAGQIEALIGKLEGRQ 88

Query: 144 ELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQS 203
           EL   ++           ++++ K    +P+G++ P         +VRD  VKAW+L+++
Sbjct: 89  ELPRAAEAVT--------IAEIRKTLDERPDGNKAPGTATSTTTSFVRDLKVKAWVLKRA 140

Query: 204 KGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKE 263
           K  CE C + APF   +G P+LEVHH+  L+ GG+DT  N VA+CPNCHR LH+SK+A+ 
Sbjct: 141 KDNCEACDQPAPFSGANG-PFLEVHHLRKLADGGSDTVTNAVAVCPNCHRRLHFSKDARA 199

Query: 264 LIEMLYVNINRLQK 277
             E +Y  +  L +
Sbjct: 200 YRETIYEKVTELVR 213


>UniRef50_A9BU78 HNH endonuclease n=4 Tax=Burkholderiales RepID=A9BU78_DELAS
          Length = 330

 Score =  142 bits (357), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 68/186 (36%), Positives = 96/186 (51%), Gaps = 7/186 (3%)

Query: 90  GNSPRDIRLKMCGYQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSELS 149
           G + +    +M       S  GR  +      + +   V  +         +  ELS   
Sbjct: 149 GRTVKAFEYRMQNISYVLSLMGRDWLTGLRPARNVGKRVACLIE------ALVLELSNSQ 202

Query: 150 QPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICEN 209
           Q    +    +R   L  K  ++P G+  P  + R    + RDP VKAW+L+++ G+CE 
Sbjct: 203 QAPVVKFEFQVR-ENLENKKQAKPAGNSNPGTIIRQVAQFERDPAVKAWVLKKAAGVCEC 261

Query: 210 CGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLY 269
           C  NAPF   DG P+LEVHH+  L+ GG+DT  N VALCPNCHR LHY   AKELIE ++
Sbjct: 262 CSSNAPFESTDGQPFLEVHHIRKLAEGGSDTVSNTVALCPNCHRALHYGMRAKELIESIF 321

Query: 270 VNINRL 275
           + +NRL
Sbjct: 322 IKVNRL 327


>UniRef50_Q2Y8M1 HNH nuclease n=1 Tax=Nitrosospira multiformis ATCC 25196
           RepID=Q2Y8M1_NITMU
          Length = 226

 Score =  139 bits (349), Expect = 1e-31,   Method: Composition-based stats.
 Identities = 72/218 (33%), Positives = 102/218 (46%), Gaps = 11/218 (5%)

Query: 62  YLASSSVRKHMHSLDERKIHPGEYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEIPSGNRT 121
                   +    L  +K +  +   + G S R     M       S  GR  +      
Sbjct: 17  AYVEMQRNERTGQLIVKKQYYKKLVEMFGRSERVFESLMQNISYVLSLMGRGWMSGLKPA 76

Query: 122 KRILINVPGIYSDSFWASIIRGELSELS-QPTDDESLLNMRVSKL-IKKTLSQPEGSRKP 179
           + I   V         A+ I   L ++S Q     +   + V +   +K L +P G+ +P
Sbjct: 77  RDIGPLV---------AARIEQLLEQISGQKAVPVAAFEIAVREAAEQKDLPKPSGNPRP 127

Query: 180 VEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGAD 239
                      RDP VKAW+LQQ+ G CE+C K APF   DG+PYLE+H+V  L+ GGAD
Sbjct: 128 KRRRISVAQLERDPNVKAWVLQQAAGTCESCEKPAPFQGADGSPYLELHYVQGLADGGAD 187

Query: 240 TTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277
              N VALCPNCHRE+HY  NA+ +   LY  + RL++
Sbjct: 188 AVSNAVALCPNCHREIHYGANAQAVEAWLYDTVQRLER 225


>UniRef50_C3K0B7 Putative 5-methylcytosine-specific restriction enzyme n=1
           Tax=Pseudomonas fluorescens SBW25 RepID=C3K0B7_PSEFS
          Length = 237

 Score =  137 bits (345), Expect = 4e-31,   Method: Composition-based stats.
 Identities = 70/190 (36%), Positives = 97/190 (51%), Gaps = 4/190 (2%)

Query: 89  IGNSPRDIRLKMCGYQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSEL 148
            G +   I  +M        R G   I      K +   V      +  A  +    S+ 
Sbjct: 50  AGRAKGSIEFRMQNISTVLVRMGWDRIEGYKPAKNVGTGVEQRIRQALAAQGV--FESDD 107

Query: 149 SQPTDDESLLNMRVSKLIKKTLSQ-PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGIC 207
           +  T DE  L  R SKL ++  +Q P+G  +P +V  +   +VRDP V+AW+L+++KGIC
Sbjct: 108 AAQTADEQTLIRRASKLQQQPFTQLPDGIAQPQKVSTVSTAFVRDPKVRAWVLKEAKGIC 167

Query: 208 ENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEM 267
           E CG NAPF   DG P+LEVHHV  L+  G+D   N VALCPNCH+  H S +     E 
Sbjct: 168 EGCGSNAPFE-VDGLPFLEVHHVKHLAQKGSDRISNAVALCPNCHQRCHRSSDRDAFTEG 226

Query: 268 LYVNINRLQK 277
           LY  + RL +
Sbjct: 227 LYAKVGRLAR 236


>UniRef50_A0KIQ7 Probable 5-methylcytosine-specific restriction enzyme A n=1
           Tax=Aeromonas hydrophila subsp. hydrophila ATCC 7966
           RepID=A0KIQ7_AERHH
          Length = 246

 Score =  134 bits (336), Expect = 4e-30,   Method: Composition-based stats.
 Identities = 70/196 (35%), Positives = 97/196 (49%), Gaps = 11/196 (5%)

Query: 84  EYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRG 143
           E     G + +    +M       +  GR  +      K +  +          A II  
Sbjct: 59  ELANQFGRTEKAFEYRMQNISYICALLGRTWVSGLKPAKNVGPHN---------APIIER 109

Query: 144 ELSELS-QPTDDESLLNMRVSKL-IKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQ 201
            L EL  QP   ++    +VS+  IK TL  P G ++P +       Y RDP VKAW+L 
Sbjct: 110 LLCELDGQPYTGKAAFEHQVSRYKIKPTLPMPIGIQEPQQRYGANTSYGRDPKVKAWVLM 169

Query: 202 QSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNA 261
            + G CE+C + APF+   G+ +LEVHH+  L+ GG+DT  N VALCPNCHRELHY  N 
Sbjct: 170 TAVGRCESCAQPAPFHATTGDAFLEVHHLRTLAEGGSDTISNTVALCPNCHRELHYGVNQ 229

Query: 262 KELIEMLYVNINRLQK 277
            +  E LY  + RL +
Sbjct: 230 AQKREALYQALPRLVR 245


>UniRef50_A6QD09 5-methylcytosine-specific restriction enzyme A n=2
           Tax=delta/epsilon subdivisions RepID=A6QD09_SULNB
          Length = 225

 Score =  132 bits (331), Expect = 1e-29,   Method: Composition-based stats.
 Identities = 64/207 (30%), Positives = 98/207 (47%), Gaps = 13/207 (6%)

Query: 74  SLDERKIHPGEYFTLI----GNSPRDIRLKMCGYQAYFSRTGRKEIPSGNRTKRILINVP 129
           SL+       +Y+  +    G + +    +M      +S  GR  +      K +   V 
Sbjct: 24  SLNGESFKKKQYYEDLSHRFGRTIKSYEYRMQNISYVYSLMGRDWLKGLRPAKNVGTRV- 82

Query: 130 GIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTL-SQPEGSRKPVEVERLQKV 188
                   + I        +Q   +       V KL+ K L  +P+   +P   +     
Sbjct: 83  -------ASEIEEIIKEIENQALSEPVSFQAEVDKLVHKKLQDKPKAVLEPKRYDIAITK 135

Query: 189 YVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALC 248
           Y RDP + AW+L  +KGICE C K APF  +DG P+LEVHH+  L+  G+D+  N +A+C
Sbjct: 136 YDRDPQIVAWVLMNAKGICECCNKEAPFVKDDGVPFLEVHHLRRLADDGSDSITNAIAIC 195

Query: 249 PNCHRELHYSKNAKELIEMLYVNINRL 275
           PNCHRELHY +N   L+  +Y  ++RL
Sbjct: 196 PNCHRELHYGQNKDILLTTIYSQVSRL 222


>UniRef50_Q1YK78 Putative 5-methylcytosine-specific restriction enzyme n=1
           Tax=Aurantimonas manganoxydans SI85-9A1
           RepID=Q1YK78_MOBAS
          Length = 125

 Score =  128 bits (321), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 53/120 (44%), Positives = 76/120 (63%), Gaps = 1/120 (0%)

Query: 157 LLNMRVSKLIKK-TLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAP 215
            L  RVS+L  + T++ P+G  +P    R   V++RDP VKA++L+++ GICE C   AP
Sbjct: 2   ELERRVSRLSARATIAFPKGIVQPKHTTRTTIVFLRDPGVKAYVLRRAGGICEACDFPAP 61

Query: 216 FYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRL 275
           F    G  +LEVHH+ PL+ GG+D   N VALCPNCHR +H++ +A +  E LY  I  +
Sbjct: 62  FKTALGGDFLEVHHLKPLAEGGSDRAQNAVALCPNCHRAMHHASDAGQRTERLYAKIGSV 121


>UniRef50_Q080H4 HNH endonuclease n=1 Tax=Shewanella frigidimarina NCIMB 400
           RepID=Q080H4_SHEFN
          Length = 309

 Score =  124 bits (311), Expect = 3e-27,   Method: Composition-based stats.
 Identities = 45/161 (27%), Positives = 74/161 (45%), Gaps = 5/161 (3%)

Query: 117 SGNRTKRILINVPGIYSDSFWASIIRGELS-----ELSQPTDDESLLNMRVSKLIKKTLS 171
           S N  K   I V  I SD F   +    ++     +L+   +      +   +L ++  +
Sbjct: 144 STNSAKESAILVGLIESDDFTVKLHDFLINIANFKQLATTGEINEATFISDDELWERICT 203

Query: 172 QPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVI 231
           +    + P +       Y R   VK + L+ + G C+ C    PF    G  +LEVHH+ 
Sbjct: 204 ENPKRKSPKKTTTETVGYERSEFVKEYALRHANGKCQLCNNAGPFATKSGRNFLEVHHID 263

Query: 232 PLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNI 272
            LS GG D  +N V LCPNCHR++H   +AK++ ++    +
Sbjct: 264 WLSKGGLDMPENVVGLCPNCHRKMHNINDAKDIKKLKSAVV 304


>UniRef50_B5EI94 HNH endonuclease n=1 Tax=Geobacter bemidjiensis Bem
           RepID=B5EI94_GEOBB
          Length = 233

 Score =  121 bits (303), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 47/173 (27%), Positives = 79/173 (45%), Gaps = 7/173 (4%)

Query: 112 RKEIPSGNRTKRILINVPGIYSDSFWASIIRGELS-------ELSQPTDDESLLNMRVSK 164
           R+++    R     + +  + +  +    +               +PT +E  ++   S 
Sbjct: 50  RQKLIHAGRVFERYLEIGSLKTSKYTDLTVNSSYILALIKAFSEKEPTMNEEKVHEFASN 109

Query: 165 LIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPY 224
            I      P+G  +P         Y RD  V+A+++ ++KG CE CG+      N  + Y
Sbjct: 110 AINDLDEIPQGVAEPERSSHTTSSYARDHKVRAYVIARAKGTCEYCGELGFLMSNGKSYY 169

Query: 225 LEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277
           LE HHVI L+  G DT DN +ALCP  H+E H+  N  E+ E + + ++ L K
Sbjct: 170 LEAHHVIALADEGRDTPDNVIALCPKHHKEAHFGINRDEIEEEMMIFLSTLSK 222


>UniRef50_A8ZWC1 HNH endonuclease n=1 Tax=Desulfococcus oleovorans Hxd3
           RepID=A8ZWC1_DESOH
          Length = 303

 Score =  121 bits (303), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 40/135 (29%), Positives = 74/135 (54%), Gaps = 4/135 (2%)

Query: 140 IIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWI 199
           I++    +L + +++     +  +  I    + P G  +P ++ R+   Y RDP +++++
Sbjct: 172 IVKKYSIDLLKSSEN----QLPSTDAINDLNAYPPGISEPEKISRMSPSYSRDPKIRSFV 227

Query: 200 LQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSK 259
           ++++KG CE CG+      +  N YLE HH+I L+  G DT +N +ALCP  HRE H+  
Sbjct: 228 IKRAKGRCEYCGEQGFLMSDGQNYYLEAHHIIALADEGEDTVENVIALCPKHHREAHFGA 287

Query: 260 NAKELIEMLYVNINR 274
           N ++L   +   I +
Sbjct: 288 NKEKLEVEMAKLIKQ 302


>UniRef50_Q3K870 Putative 5-methylcytosine-specific restriction enzyme n=1
           Tax=Pseudomonas fluorescens Pf0-1 RepID=Q3K870_PSEPF
          Length = 237

 Score =  118 bits (296), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 59/194 (30%), Positives = 84/194 (43%), Gaps = 12/194 (6%)

Query: 88  LIGNSPRDIRLKMCGYQAYFSRTGRKEI----PSGNRTKRILINVPGIYSDSFWASIIRG 143
           L   S   +  +M    A     G   I     + N    ++  +  I +     +I   
Sbjct: 49  LSKRSASSVEYRMQNISAVMDLMGLPRITGYVSAKNLGSGVITRIKEILAKKDMEAIRNS 108

Query: 144 ELSELSQPTDDESLLNMRVSKLIKKTLSQ-PEGSRKPVEVERLQKVYVRDPMVKAWILQQ 202
                        L   R+ +     L+  P G   P +         R   VK W+L++
Sbjct: 109 -------SRRGTQLTRFRLIEPSAPELNDAPPGVLNPKQTSATVVRLSRKLNVKKWVLKR 161

Query: 203 SKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAK 262
           S+GICE CG+ APF   DG P+LEVHH+  L +GG D T N VALCPNCHR  HYS + +
Sbjct: 162 SQGICEGCGQKAPFQDADGKPFLEVHHLKHLVNGGTDRTSNAVALCPNCHRRCHYSSDKE 221

Query: 263 ELIEMLYVNINRLQ 276
           E     Y ++  L+
Sbjct: 222 EFTAKFYRSVEGLE 235


>UniRef50_C4WNE8 Putative uncharacterized protein n=1 Tax=Ochrobactrum intermedium
           LMG 3301 RepID=C4WNE8_9RHIZ
          Length = 282

 Score =  118 bits (295), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 40/137 (29%), Positives = 64/137 (46%), Gaps = 2/137 (1%)

Query: 140 IIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWI 199
                L  + +  DDE  +       ++    Q  GSR+     R   +Y R   V+ ++
Sbjct: 143 FELRNLENIVEAVDDEQPVPAVDLAAMRDLARQAAGSREGKASTRT--IYERSRHVRDYV 200

Query: 200 LQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSK 259
           L ++ G CE C   APF   +G PYLE HH+  +S GG D     +ALCP CHR++H+ +
Sbjct: 201 LARANGHCEGCSCQAPFLRINGQPYLEPHHIRRVSDGGPDDPSYVIALCPTCHRKVHHGQ 260

Query: 260 NAKELIEMLYVNINRLQ 276
                 + L   +  ++
Sbjct: 261 GGATYNDTLLKKMPSIE 277


>UniRef50_C7HJ98 HNH endonuclease n=1 Tax=Clostridium thermocellum DSM 2360
           RepID=C7HJ98_CLOTM
          Length = 276

 Score =  117 bits (293), Expect = 4e-25,   Method: Composition-based stats.
 Identities = 46/134 (34%), Positives = 71/134 (52%), Gaps = 1/134 (0%)

Query: 144 ELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQS 203
           E S +    + E +        +K+   Q E S K    +    V++RD  V  +  +++
Sbjct: 144 EESFIKYIKEKEKVAEKLTLNELKERAEQNE-SDKVSSRKVTSNVFIRDAFVAEYAKRRA 202

Query: 204 KGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKE 263
            G+C+ CG+ APF   +G PYLE HH+  LS GG+DT +N VALCPNCHR++H    + +
Sbjct: 203 NGVCQLCGQKAPFNNKEGIPYLECHHIEWLSEGGSDTIENTVALCPNCHRKMHILNLSSD 262

Query: 264 LIEMLYVNINRLQK 277
             ++      RL K
Sbjct: 263 KEKLKIQAKIRLSK 276


>UniRef50_D0Z3H8 HNH nuclease n=1 Tax=Photobacterium damselae subsp. damselae CIP
           102761 RepID=D0Z3H8_LISDA
          Length = 278

 Score =  116 bits (290), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 46/110 (41%), Positives = 67/110 (60%), Gaps = 1/110 (0%)

Query: 150 QPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICEN 209
               ++S++        K+     + ++KP  + R+ K Y R+P + A  L ++ GICE 
Sbjct: 169 FTNFEQSVIKSLQDNPKKRRQRIEKANKKPQLISRVVKDYQRNPDIVAEALIRAAGICEA 228

Query: 210 CGKNAPF-YLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258
           CG  APF   ++G PYLEVHH+IPLS GG D+ DN  +LCPNCHR+LH+ 
Sbjct: 229 CGCQAPFNKKSNGEPYLEVHHLIPLSKGGEDSLDNVQSLCPNCHRKLHFG 278


>UniRef50_C3FAM5 HNH nuclease n=4 Tax=Bacillus cereus group RepID=C3FAM5_BACTU
          Length = 350

 Score =  114 bits (286), Expect = 3e-24,   Method: Composition-based stats.
 Identities = 47/123 (38%), Positives = 69/123 (56%), Gaps = 1/123 (0%)

Query: 137 WASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVK 196
           +   +    ++  +   D  +   ++S    +     + +RKP  VE +   Y R+P V 
Sbjct: 228 YYQTLHALTNQEYENDLDIKVKQSQISNGSARKERLKKAARKPDVVEVVTTQYKRNPDVI 287

Query: 197 AWILQQSKGICENCGKNAPFYL-NDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHREL 255
           A +L+++ G CE C + APF    DG PYLEVHHVIPL+ GG D+ +N V LCPNCHR+ 
Sbjct: 288 AEVLERANGYCEECKQEAPFKRAKDGTPYLEVHHVIPLAQGGEDSVENAVGLCPNCHRKA 347

Query: 256 HYS 258
           HY 
Sbjct: 348 HYG 350


>UniRef50_Q312Y0 HNH nuclease n=1 Tax=Desulfovibrio desulfuricans subsp.
           desulfuricans str. G20 RepID=Q312Y0_DESDG
          Length = 260

 Score =  114 bits (285), Expect = 3e-24,   Method: Composition-based stats.
 Identities = 57/197 (28%), Positives = 81/197 (41%), Gaps = 5/197 (2%)

Query: 64  ASSSVRKHMHSLDERKIHPGEYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEIPSGNRTKR 123
            +S  +  + ++D+        F     +PR   L   G               G+    
Sbjct: 55  KNSMKQAILQAIDDFARGVRPAF---YKTPRRWYLVHRGSLYPAKAIWAMATGQGSAGSF 111

Query: 124 ILINVP-GIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEV 182
              +   G+    F       E  +        ++  ++ +          E    P   
Sbjct: 112 NTRDARAGLAEAGFAVRAFEPESVQWPDEDVRLAIRQLQQAADTDPGDDAAETLCPPGMT 171

Query: 183 ERLQKVYVRDPMVKAWILQQSKGICENCGKNAPF-YLNDGNPYLEVHHVIPLSSGGADTT 241
            R Q V+ R P+V A +L ++ G CE CG  APF    D  PYLEVHHV PL+ GGADT 
Sbjct: 172 VREQAVFRRSPVVAARVLLRAGGFCECCGAPAPFVSRADNLPYLEVHHVRPLAEGGADTP 231

Query: 242 DNCVALCPNCHRELHYS 258
            NC+ALCPNCHR+ HY 
Sbjct: 232 ANCMALCPNCHRQFHYG 248


>UniRef50_C4SUH5 Restriction endonuclease n=1 Tax=Yersinia frederiksenii ATCC 33641
           RepID=C4SUH5_YERFR
          Length = 238

 Score =  114 bits (284), Expect = 4e-24,   Method: Composition-based stats.
 Identities = 58/188 (30%), Positives = 88/188 (46%), Gaps = 16/188 (8%)

Query: 83  GEYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEIPSGNR---TKRILI--NVPGIYSDSFW 137
             Y  LI N+    R         F+RT R+   + +R     R+    NV  +Y  +  
Sbjct: 47  NTYLNLIVNAVNCNRGH-----WSFNRTARRTDDATHRHHEYDRLFKRGNVFEVYDSALH 101

Query: 138 ASIIRGELS---ELSQPTDDESLLNMRVSKLIKKTLSQPE---GSRKPVEVERLQKVYVR 191
                 E S    L++P   E    +  +  +     + +    +  P  V      + R
Sbjct: 102 GVFEIYEASDGKWLTRPVKSEFEKAIETASQLTSEQRREKLATANTTPERVIIKSYTFKR 161

Query: 192 DPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNC 251
           +P+V A +L  + G C++C ++APF   DG PYLEVHHV  L++GG D+ +N +ALCPNC
Sbjct: 162 NPLVVAEVLALAGGKCQSCLRDAPFKREDGRPYLEVHHVEWLANGGEDSVENAIALCPNC 221

Query: 252 HRELHYSK 259
           HRE HY  
Sbjct: 222 HREAHYGA 229


>UniRef50_A2SMM5 Putative uncharacterized protein n=1 Tax=Methylibium petroleiphilum
           PM1 RepID=A2SMM5_METPP
          Length = 220

 Score =  114 bits (284), Expect = 5e-24,   Method: Composition-based stats.
 Identities = 48/116 (41%), Positives = 67/116 (57%), Gaps = 2/116 (1%)

Query: 144 ELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQS 203
           +L EL    + +     ++S   ++ + +  G  KP  V     V++R+P V A +L ++
Sbjct: 106 DLLELHAEFERQVNECAQMSSAERRNMFET-GQAKPERVIVQTTVFMRNPAVAAEVLLRA 164

Query: 204 KGICENCGKNAPFYL-NDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258
            G CE C ++APF    DG PYLEVHH  PLS GG DT  N +ALCPNCHR  HY+
Sbjct: 165 NGHCELCRQSAPFKRRKDGTPYLEVHHRKPLSDGGNDTVQNAIALCPNCHRRAHYA 220


>UniRef50_A3JQK6 HNH nuclease n=1 Tax=Rhodobacterales bacterium HTCC2150
           RepID=A3JQK6_9RHOB
          Length = 371

 Score =  114 bits (284), Expect = 5e-24,   Method: Composition-based stats.
 Identities = 54/185 (29%), Positives = 86/185 (46%), Gaps = 10/185 (5%)

Query: 83  GEYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIR 142
           G +     ++   I+       A+   T + +     R     I+       + W +++ 
Sbjct: 184 GTFKETYQDNAAIIKNPQNPVLAFVRNTPKDKFTYWGRYFPSSIHTE--TEGAKWFTLVE 241

Query: 143 GE--LSELSQPTDDESLLNMRVSKLIK-----KTLSQPEGSRKPVEVERLQKVYVRDPMV 195
               LS+L      E+ L  +V K +K     +     +  + P + +    ++ R+P V
Sbjct: 242 WSDGLSDLQSVAAAETSLVEQVQKSLKLDPKARQKRLADAPKLPEKQKATTTIFKRNPDV 301

Query: 196 KAWILQQSKGICENCGKNAPF-YLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254
            A +L ++ G CE C ++APF   +DG PYLEVHH IPL+  G D+ DN VALCPNCHR 
Sbjct: 302 IAEVLFRANGTCEGCRQSAPFDRRSDGTPYLEVHHKIPLAKDGHDSVDNAVALCPNCHRR 361

Query: 255 LHYSK 259
            H   
Sbjct: 362 EHSGP 366


>UniRef50_C3LV13 HNH endonuclease n=13 Tax=Vibrio RepID=C3LV13_VIBCM
          Length = 234

 Score =  113 bits (283), Expect = 5e-24,   Method: Composition-based stats.
 Identities = 45/212 (21%), Positives = 79/212 (37%), Gaps = 35/212 (16%)

Query: 75  LDERKIHPG-----EYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEIPSGN--RTKRILIN 127
            DE    PG     E+ +LI N+    RLK    Q   + TG  +I S +    ++ L  
Sbjct: 45  FDESWKGPGRKQSLEHISLIQNN--GYRLKTFPMQYDQTETGTAKIKSFDWILEEKHLAG 102

Query: 128 VPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQK 187
           V G+     W ++   E  +++                  + +  PE   +    E    
Sbjct: 103 VDGL-----WYALNYSESVDITSI----------------EEVVHPETYIEGATKEISVN 141

Query: 188 VYVRDPMVKAWILQQSKGICENCGKNA-PFYLNDGNPYLEVHHVIPLS----SGGADTTD 242
            Y R+P  +A  +      C  C  +    Y + G  ++ VHH + L+        D   
Sbjct: 142 AYERNPDARAKCILHYGCKCYVCKFDFQEVYGDIGKGFIHVHHEVSLAEIKKEYSVDPIK 201

Query: 243 NCVALCPNCHRELHYSKNAKELIEMLYVNINR 274
           +   LCPNCH  +H +     +  ++ +  +R
Sbjct: 202 DLKPLCPNCHGIIHRTHPPISVDSLINLLRSR 233


>UniRef50_D0KA86 HNH endonuclease n=2 Tax=Enterobacteriaceae RepID=D0KA86_PECWW
          Length = 240

 Score =  113 bits (283), Expect = 6e-24,   Method: Composition-based stats.
 Identities = 52/149 (34%), Positives = 79/149 (53%), Gaps = 10/149 (6%)

Query: 120 RTKRILINVPGIY-----SDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPE 174
           R  R  I  P I+      +  +      E+  + +    ++   + V K  + T  + +
Sbjct: 92  RGDRYEIYQPSIHGVWELYEDIYGKWCFREIETIDEAKRLQAEFEIEVRKASQLTSKERK 151

Query: 175 ----GSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPF-YLNDGNPYLEVHH 229
                S  P   E + K++VR+P V A +L +++G CE C +NAPF    DG PYLEVHH
Sbjct: 152 QHLAVSNFPEMKEVITKIFVRNPYVVAEVLHRAQGKCELCKRNAPFLRGKDGTPYLEVHH 211

Query: 230 VIPLSSGGADTTDNCVALCPNCHRELHYS 258
            +PLS GG DT +N +A+CPNCHR+ H+ 
Sbjct: 212 CVPLSQGGEDTVENAIAVCPNCHRQAHFG 240


>UniRef50_C6ANH6 HNH nuclease n=1 Tax=Aggregatibacter aphrophilus NJ8700
           RepID=C6ANH6_AGGAN
          Length = 194

 Score =  107 bits (268), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 41/110 (37%), Positives = 60/110 (54%), Gaps = 1/110 (0%)

Query: 150 QPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICEN 209
           + +  E ++         +       S+ P++       + R+P V A +L ++ G CE 
Sbjct: 85  ESSFIEQIIESLNDTSENRKRRLKSQSKHPIKKIIEVLQFQRNPDVVAEVLVRANGYCEK 144

Query: 210 CGKNAPFYLN-DGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258
           C K APF    +  PYLEVHH+IPLS  G DT +NC+ALCPNCHR+ H+ 
Sbjct: 145 CKKPAPFIRKANLQPYLEVHHIIPLSKDGEDTVENCMALCPNCHRQEHFG 194


>UniRef50_C0WRI9 Possible HNH endonuclease n=1 Tax=Lactobacillus buchneri ATCC 11577
           RepID=C0WRI9_LACBU
          Length = 193

 Score =  107 bits (268), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 43/135 (31%), Positives = 72/135 (53%), Gaps = 2/135 (1%)

Query: 140 IIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVE-VERLQKVYVRDPMVKAW 198
           I   E+   S+   ++++  M + KLI+   +  +G        E    ++VR+   +  
Sbjct: 49  IANKEVLHQSEIKQEQAVKKMPIKKLIESVKTHEQGKTAKTSCREVTTTMFVRNANNRHL 108

Query: 199 ILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258
            L  SKG+C+ CG+ APF    G PYLEVHH+   S GG D  +N +A+CPNCHR++H  
Sbjct: 109 ALYFSKGVCQLCGEPAPFKDKTGQPYLEVHHIDWFSQGGKDVIENEIAICPNCHRKMHII 168

Query: 259 KNAKELIEMLYVNIN 273
           ++  +++ +L     
Sbjct: 169 QDPNDVL-LLKEKAR 182


>UniRef50_A4SC99 HNH endonuclease n=1 Tax=Chlorobium phaeovibrioides DSM 265
           RepID=A4SC99_PROVI
          Length = 222

 Score =  106 bits (265), Expect = 7e-22,   Method: Composition-based stats.
 Identities = 42/108 (38%), Positives = 56/108 (51%), Gaps = 1/108 (0%)

Query: 152 TDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCG 211
           T+   +   R    + +        ++P         Y R+P +    L +++G CENC 
Sbjct: 115 TETAEIAKSRTDTSVARNERILNAEKRPKRQRVYSYTYQRNPDIVVEALHRAEGFCENCK 174

Query: 212 KNAPFYLN-DGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258
             APF    DG P+LEVHH+  LS GG DT +N VALCPNCHRE HY 
Sbjct: 175 NPAPFKRASDGTPFLEVHHIRSLSDGGEDTLENVVALCPNCHREKHYG 222


>UniRef50_C0ZFI2 Putative uncharacterized protein n=1 Tax=Brevibacillus brevis NBRC
           100599 RepID=C0ZFI2_BREBN
          Length = 360

 Score =  106 bits (264), Expect = 1e-21,   Method: Composition-based stats.
 Identities = 55/221 (24%), Positives = 84/221 (38%), Gaps = 22/221 (9%)

Query: 73  HSLD-ERKIHPGEYFTL---IGNSPRDIRLKMCGYQAYFSRTGRKEIPSGNRTKRILINV 128
            SLD +R I P E   L     N+       +CG   Y+       +P   + K  L N+
Sbjct: 128 QSLDIDRTIFPNESIDLKASTTNAKNYTAAHICG--KYYDALA---LPDDEQLKVDLKNL 182

Query: 129 PGIYSD---SFWASIIRGELSELSQPTD-DESLLNMRVSKLIKKTLSQPEGSRKPVEVER 184
             IY               L    Q  + +++     V                P     
Sbjct: 183 LKIYEQLKIQMAGRGTEEMLDYYLQKEEIEDTQFQSDVQVAEPSNTPLVPQPVPPQVESN 242

Query: 185 LQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLND-GNPYLEVHHVIPLS-----SGGA 238
            ++ + R+  +    L+    +CE    +  F        ++E HH+IP+      S   
Sbjct: 243 GKQQWKRNASIAKEALRNEDYLCEVNNGHLSFTSAITNKNFVEAHHLIPMKLQALFSWSL 302

Query: 239 DTTDNCVALCPNCHRELHY--SKNAKELIEMLYV-NINRLQ 276
           D   N V+LCPNCHR++H+      KELIE+LY   INRL+
Sbjct: 303 DVPGNIVSLCPNCHRKIHHASKSERKELIEVLYSKKINRLK 343


>UniRef50_C0N619 HNH endonuclease domain protein n=1 Tax=Methylophaga thiooxidans
           DMS010 RepID=C0N619_9GAMM
          Length = 274

 Score =  105 bits (262), Expect = 2e-21,   Method: Composition-based stats.
 Identities = 43/128 (33%), Positives = 67/128 (52%), Gaps = 8/128 (6%)

Query: 150 QPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICEN 209
           +    +SLL +R + L K + ++          ER Q  Y R   ++ ++ +++ G CE 
Sbjct: 152 KDLRKKSLLELREAALEKPSHTKNA-------SERRQSAYYRSKALRLYVRKRAGGKCEA 204

Query: 210 CGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLY 269
           C   APF    G PY+E HH+  ++ GG D   N + LCPNCHR  HY+KN +E  + L 
Sbjct: 205 CAVPAPFESRKG-PYIECHHLHRVADGGPDHPMNVIGLCPNCHRRAHYAKNFREFNDSLK 263

Query: 270 VNINRLQK 277
             +  L+K
Sbjct: 264 PVVRELEK 271


>UniRef50_C8U495 Endonuclease-like protein n=2 Tax=Escherichia coli
           RepID=C8U495_ECO10
          Length = 246

 Score =  105 bits (261), Expect = 2e-21,   Method: Composition-based stats.
 Identities = 52/246 (21%), Positives = 90/246 (36%), Gaps = 28/246 (11%)

Query: 38  KDYNIALDYIIE---RLVDSGVSQVVVYLASSS-VRKHMHSLDERKIHPGEYFTLIGNSP 93
           K+YN +  +I E   R++      +      S  +  H   +D +      Y   I +  
Sbjct: 15  KNYNWSWSFIDETNKRIIFGAWDHLKSADGKSVLILSHDWRVDSQGRKKPGYKQSIEHIN 74

Query: 94  RDIRLKMCGYQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSELSQPTD 153
           +   +   GY  Y     R+E  + +   +I           F  +I+R  L++++    
Sbjct: 75  K---ILYDGYSLYIFYQIRQEKTTASGAAKIK---------DFEKNIVRKYLTKINSNWY 122

Query: 154 DESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN 213
                +   +  I           +  ++ERL   Y RDP  +   +      C  CG N
Sbjct: 123 ATDEEHYSYTPEIDNDY------YEGRQLERLATYYERDPKARQACIDAHGYTCHICGFN 176

Query: 214 -APFYLNDGNPYLEVHHVIPLSS----GGADTTDNCVALCPNCHRELHYSKNAKELIEML 268
               Y + G  Y++VHH+ PL         D  ++ + LC NCH  +H        IE L
Sbjct: 177 FEKVYGSIGKNYIQVHHIKPLHHIAKYHKVDPVNDLIPLCANCHVMIHNG-MEVRTIEQL 235

Query: 269 YVNINR 274
              + R
Sbjct: 236 REILER 241


>UniRef50_D2C2V7 HNH endonuclease n=1 Tax=Dickeya dadantii Ech586 RepID=D2C2V7_DICD5
          Length = 245

 Score =  105 bits (261), Expect = 2e-21,   Method: Composition-based stats.
 Identities = 55/128 (42%), Positives = 71/128 (55%), Gaps = 9/128 (7%)

Query: 140 IIRGELSELSQPTDDESL---LNMRVSKLIKKTLSQPEGS-----RKPVEVERLQKVYVR 191
           II    SELS+    E+L    N++V+K I       +       + P +     + ++R
Sbjct: 115 IIEFYESELSKTDSFENLTTEFNIQVNKSIADNQRSRQERLSTSPKYPQKKSLQIEFFIR 174

Query: 192 DPMVKAWILQQSKGICENCGKNAPFYLN-DGNPYLEVHHVIPLSSGGADTTDNCVALCPN 250
           +P V A +L ++ G CE C  NAPF    D  PYLEVHH  PLS GGADT DN +ALCPN
Sbjct: 175 NPDVVAEVLLRANGKCERCCSNAPFLRKKDNTPYLEVHHKTPLSEGGADTVDNAIALCPN 234

Query: 251 CHRELHYS 258
           CHR LHY 
Sbjct: 235 CHRYLHYG 242


>UniRef50_C9PPM2 5-methylcytosine-specific restriction enzyme A n=1 Tax=Pasteurella
           dagmatis ATCC 43325 RepID=C9PPM2_9PAST
          Length = 200

 Score =  104 bits (259), Expect = 3e-21,   Method: Composition-based stats.
 Identities = 48/149 (32%), Positives = 72/149 (48%), Gaps = 7/149 (4%)

Query: 120 RTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGS--- 176
               +   V      +     I  + + L    + +S  + +V K +  +  + +     
Sbjct: 52  PANAVNTRVAAKELRNLGFEAIDIQTNALYPNQNFDSEFDKKVKKALHDSPEKRQKRLDR 111

Query: 177 ---RKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLN-DGNPYLEVHHVIP 232
              +KP       + + RDP V A +L Q+ G+C  C K APF    D  PYLEVHH IP
Sbjct: 112 KKIKKPSYSFVKIRQFHRDPDVVAEVLYQANGVCGACKKPAPFNRKVDNMPYLEVHHKIP 171

Query: 233 LSSGGADTTDNCVALCPNCHRELHYSKNA 261
           LS  G D+  NC+ALCPNCHR++H+  N+
Sbjct: 172 LSQNGDDSVSNCIALCPNCHRKIHFGNNS 200


>UniRef50_Q8TKB6 Hnh endonuclease n=2 Tax=Methanosarcina RepID=Q8TKB6_METAC
          Length = 279

 Score =  104 bits (259), Expect = 3e-21,   Method: Composition-based stats.
 Identities = 34/167 (20%), Positives = 65/167 (38%), Gaps = 8/167 (4%)

Query: 114 EIPSGNRTKRILINVPGIYSD-SFWASIIRGELSELSQPTD--DESLLNMRVSKLIKKTL 170
            I +     R ++   G + D +     +     EL Q  +   +       S+  + T 
Sbjct: 108 VIGTEGNKSRFIVPFEGWHEDYNPSKHFVWKLRDELVQALEELGKVDYQTFPSEKDELTS 167

Query: 171 SQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHH 229
           S  E + +  ++      Y R+   +   +     +C+ CG +    Y   G  Y+EVHH
Sbjct: 168 SIVESTPEGKKILCYTTRYERNAQNRRNAIAIHGTVCQGCGFDFEKTYGEIGRDYIEVHH 227

Query: 230 VIPLSSGG----ADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNI 272
           V PL         +   + + +C NCHR +H  K++   ++ L   +
Sbjct: 228 VKPLCEEEGSVPINAETDLICVCANCHRMIHRRKDSVLSLKELQELL 274


>UniRef50_B1ZSH9 Restriction endonuclease-like protein n=1 Tax=Opitutus terrae
           PB90-1 RepID=B1ZSH9_OPITP
          Length = 261

 Score =  104 bits (258), Expect = 5e-21,   Method: Composition-based stats.
 Identities = 32/165 (19%), Positives = 60/165 (36%), Gaps = 6/165 (3%)

Query: 106 YFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKL 165
           Y+     K +      + ++    G   D+   +          +      +  +    L
Sbjct: 83  YYFSVNEKVLRKTRSFRDVVGLALGAGHDARTRTDRNPPAIHARKA---AGVEILPAGDL 139

Query: 166 IKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNA-PFYLNDGNPY 224
           ++    +PEG  +P     +      DP  +   ++    +C+ CG      Y   G  +
Sbjct: 140 VRGDFEEPEGFFRPGVATVVIDRLEHDPFARRACIEHYGSVCQACGMRFDKVYGKIGAGF 199

Query: 225 LEVHHVIPLSS--GGADTTDNCVALCPNCHRELHYSKNAKELIEM 267
           +EVH + P+S     AD     + LC NCHR +H    A  + E+
Sbjct: 200 IEVHRLRPVSRPVDSADPVKELIPLCSNCHRMIHRRSPALSVAEL 244


>UniRef50_Q60BH4 Putative uncharacterized protein n=1 Tax=Methylococcus capsulatus
           RepID=Q60BH4_METCA
          Length = 311

 Score =  104 bits (258), Expect = 5e-21,   Method: Composition-based stats.
 Identities = 26/107 (24%), Positives = 43/107 (40%), Gaps = 5/107 (4%)

Query: 165 LIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNA-PFYLNDGNP 223
           L+ + + +P+   +          Y R+P  +   ++     C  CG      Y   G  
Sbjct: 198 LLPEQIDEPQEFYEGASKSITVNAYERNPQARNACIEHYGAKCIICGFVFHEKYGEIGKG 257

Query: 224 YLEVHHVIPL----SSGGADTTDNCVALCPNCHRELHYSKNAKELIE 266
           ++ VHH+ PL    +    D  ++   +CPNCH  LH  K    L E
Sbjct: 258 FIHVHHIKPLGEICAEYQVDPINDLCPVCPNCHAMLHMRKPPYSLNE 304


>UniRef50_C9XQW3 Putative uncharacterized protein n=2 Tax=Clostridium difficile
           RepID=C9XQW3_CLODC
          Length = 375

 Score =  103 bits (257), Expect = 6e-21,   Method: Composition-based stats.
 Identities = 38/176 (21%), Positives = 69/176 (39%), Gaps = 9/176 (5%)

Query: 103 YQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRV 162
           +  Y+ +    +I       +I        + +           ++ +    ++ LN+  
Sbjct: 201 FSEYYEKFLENKIEGKTNLPKIRFIKLDSNNFNIEFIFTAEIEDDVLEEISQDNPLNINT 260

Query: 163 SKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDG 221
             +  +T  + EG  K        K Y R+P  +   ++     C  CG +    Y + G
Sbjct: 261 INIELETEIRKEGKVK----YVYGKQYERNPRNRIEAIKYHGTKCIVCGFDFEKTYGDRG 316

Query: 222 NPYLEVHHVIPLSSGG----ADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNIN 273
             Y+E+HH+ PLSS G     +   + V +C NCHR +H  K+    I+ L   I 
Sbjct: 317 KGYIEIHHIKPLSSVGEESNINPKTDLVPICSNCHRMIHRKKDNVLSIDDLKQIIK 372


>UniRef50_C2KXT9 Putative uncharacterized protein n=1 Tax=Oribacterium sinus F0268
           RepID=C2KXT9_9FIRM
          Length = 324

 Score =  103 bits (257), Expect = 6e-21,   Method: Composition-based stats.
 Identities = 39/117 (33%), Positives = 66/117 (56%)

Query: 151 PTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENC 210
           PT D+ L   +      K   +    + P +     +V  R  +V + + +++ G+C+ C
Sbjct: 201 PTVDKGLAKKKSKLSQLKKDLKDFDKQHPKKKLTEVEVVQRSSLVSSIVKERAAGVCQLC 260

Query: 211 GKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEM 267
            K APFY   G  YLE HHV+ ++ GGAD  +N VALCPNCHR++H   +++++ ++
Sbjct: 261 NKPAPFYNKSGEAYLECHHVVWIAKGGADEVNNAVALCPNCHRKMHILDDSEDVEKL 317


>UniRef50_A0L1U4 HNH endonuclease n=1 Tax=Shewanella sp. ANA-3 RepID=A0L1U4_SHESA
          Length = 224

 Score =  103 bits (257), Expect = 6e-21,   Method: Composition-based stats.
 Identities = 40/200 (20%), Positives = 66/200 (33%), Gaps = 13/200 (6%)

Query: 83  GEYFTLIGNSPRD------IRLKMCGYQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSF 136
            E         RD      +R    G +       + E+ S N       +   +     
Sbjct: 20  EEISDSTLRVTRDNDGEIFVRDFSIGDRFITYAKLKVEMESLNPNGGSEESGYYLIVREV 79

Query: 137 WASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGS--RKPVEVERLQKVYVRDPM 194
            +S    +    +Q   D+       ++  K      +G    +      L   Y RD  
Sbjct: 80  TSSGTGKKTDVSAQNQIDKLYFGQVDNEEFKSPQEVDDGEVYTEGSVKRVLVNKYERDAK 139

Query: 195 VKAWILQQSKGICENCGKNA-PFYLNDGNPYLEVHHVIPLS----SGGADTTDNCVALCP 249
            +   +      C+ CG N    Y   G  ++EVHH+ PLS    S   D  ++ + +C 
Sbjct: 140 ARKACIAHHGCQCKVCGFNFSETYGLHGEGFIEVHHITPLSTISKSYQVDPINDLIPVCS 199

Query: 250 NCHRELHYSKNAKELIEMLY 269
           NCH  LH  K    + E+  
Sbjct: 200 NCHSMLHRGKEPLSIDELTK 219


>UniRef50_Q9L0M9 Putative uncharacterized protein SCO4631 n=3 Tax=Streptomyces
           RepID=Q9L0M9_STRCO
          Length = 560

 Score =  103 bits (256), Expect = 8e-21,   Method: Composition-based stats.
 Identities = 35/123 (28%), Positives = 54/123 (43%), Gaps = 5/123 (4%)

Query: 160 MRVSKLIKKTLSQPEGSRKPV---EVERLQKVYVRDPMVKAWILQQSKGICEN--CGKNA 214
               +  ++   + E + +     +   +   YVRDP  +  +L++ +  CEN  C  + 
Sbjct: 434 ESDDEAYRRLAQKAEANAERRGQLKKPTVADKYVRDPSARGAVLKRCQKRCENPECAGHP 493

Query: 215 PFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINR 274
                 G P L+V HV  L+ GG D   N +ALCPNCH    Y  N   L  +L     R
Sbjct: 494 TELTKAGLPILQVDHVNDLAKGGPDVPWNMIALCPNCHALKTYGANKVRLQRLLAATARR 553

Query: 275 LQK 277
           L +
Sbjct: 554 LHE 556


>UniRef50_A9AZQ2 HNH endonuclease n=1 Tax=Herpetosiphon aurantiacus ATCC 23779
           RepID=A9AZQ2_HERA2
          Length = 271

 Score =  102 bits (254), Expect = 1e-20,   Method: Composition-based stats.
 Identities = 34/153 (22%), Positives = 62/153 (40%), Gaps = 20/153 (13%)

Query: 119 NRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRK 178
           +  K+ + NV  +  D  W++ I+  L +L                   + ++ PE   +
Sbjct: 127 DLRKQSIQNVSTVEED--WSAAIQANLFDLPSTQP-------------HQPIASPEIFIE 171

Query: 179 PVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSSGG 237
             E + L   Y R+P  +   ++     C  C  + A  Y      ++ VHH+ PL++ G
Sbjct: 172 GAEYQSLVTRYERNPEARQRCIEHYGSTCVICHFDFAKVYGELAKGFIHVHHLKPLATIG 231

Query: 238 A----DTTDNCVALCPNCHRELHYSKNAKELIE 266
                +  D+   +CPNCH  +H  K    + E
Sbjct: 232 ENYEVNPIDDLRPVCPNCHAVIHMRKEPYTIDE 264


>UniRef50_Q0BZ66 Conserved domain protein n=1 Tax=Hyphomonas neptunium ATCC 15444
           RepID=Q0BZ66_HYPNA
          Length = 343

 Score =  102 bits (254), Expect = 1e-20,   Method: Composition-based stats.
 Identities = 45/139 (32%), Positives = 66/139 (47%), Gaps = 5/139 (3%)

Query: 139 SIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAW 198
           ++   E  E  +   D S+ ++R S     T  +    ++   V R      R   +KA+
Sbjct: 206 AVADSETDEEIEDQPDTSIDDLRTSAYEAATAVRNSNPKEARRVYR-----QRSAKIKAY 260

Query: 199 ILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258
           IL ++ G+CE  G+ APF    G+PYLEVHH   LS  G D      A+ P  HRE+H+ 
Sbjct: 261 ILARAGGVCELTGEKAPFLTKSGHPYLEVHHTQRLSDDGLDHPRWVAAISPTAHREIHFG 320

Query: 259 KNAKELIEMLYVNINRLQK 277
           +   EL E L   I   +K
Sbjct: 321 ERGDELNERLKEIIAEKEK 339


>UniRef50_C3RB64 Predicted protein n=1 Tax=Bacteroides dorei 5_1_36/D4
           RepID=C3RB64_9BACE
          Length = 274

 Score =  102 bits (253), Expect = 2e-20,   Method: Composition-based stats.
 Identities = 33/137 (24%), Positives = 53/137 (38%), Gaps = 6/137 (4%)

Query: 142 RGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQ 201
              L EL + + +     + ++ + ++   Q     +    E     Y R+P+ +   L 
Sbjct: 137 ESILVELVRYSFELIFSLLTITDISEEEFLQKAVQTEGTIQEIKSIRYERNPINRKLCLY 196

Query: 202 QSKGICENCGKNA-PFYLNDGNPYLEVHHVIPLSSGGA----DTTDNCVALCPNCHRELH 256
           +    C  CG N    Y + G  ++EVHH  P+S  G     D   + V LC NCH   H
Sbjct: 197 KKGYTCAVCGMNFQDVYGDIGKGFIEVHHTTPVSKMGEGYNLDIERDLVPLCSNCHSMTH 256

Query: 257 YSKNAKELIEMLYVNIN 273
                  + E L   I 
Sbjct: 257 RRNPPYSV-EELKEIIK 272


>UniRef50_C4L1L5 HNH endonuclease n=2 Tax=Bacillales RepID=C4L1L5_EXISA
          Length = 346

 Score =  101 bits (252), Expect = 2e-20,   Method: Composition-based stats.
 Identities = 39/139 (28%), Positives = 59/139 (42%), Gaps = 12/139 (8%)

Query: 141 IRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWIL 200
           + GEL +      D+ L     +  + ++L   EG RK V V      Y R+P+ +   +
Sbjct: 204 LMGELKDYITSFFDKDLTAEYYADEVAESLE--EGKRKVVTVN----TYERNPLARKRCM 257

Query: 201 QQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSSGG----ADTTDNCVALCPNCHREL 255
           +     C+ C  N    Y   G  ++ VHH+ PL   G     D   +   +CPNCH  L
Sbjct: 258 EYYGVSCQVCQINFEKIYGEVGRDFIHVHHIKPLHEIGQNYVVDPITDLRPVCPNCHAML 317

Query: 256 HYSKNAKEL-IEMLYVNIN 273
           H  +  + L IE L   I 
Sbjct: 318 HRKEGGEYLTIEQLKNRIK 336


>UniRef50_Q0F8W7 Putative uncharacterized protein n=1 Tax=Rhodobacterales bacterium
           HTCC2255 RepID=Q0F8W7_9RHOB
          Length = 228

 Score =  101 bits (252), Expect = 2e-20,   Method: Composition-based stats.
 Identities = 46/206 (22%), Positives = 75/206 (36%), Gaps = 44/206 (21%)

Query: 48  IERLVDSGVSQVVVYLASSSVRKHMHSLDERKIHPGEYFTLIGNSPRDIRLKMCGYQAYF 107
           IER+ D   S+  +    +  +KH++S DE        F  I N  +             
Sbjct: 57  IERIFDGSFSKACIAAGVNIKKKHIYSFDE-------LFEHIENVAK------------- 96

Query: 108 SRTGRKEIPS-GNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLI 166
               R +IPS G+  K    +   +  D++     R   S  +         N ++SK  
Sbjct: 97  ---WRNQIPSIGDLKKYNKKHNTSLTYDAY----ARRWGSWKNFLKVFVQFKNNQISKHE 149

Query: 167 KKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLE 226
               S+    RK +               +A +L +    C +CG+       D    L 
Sbjct: 150 LIDASKKSLRRKAI-----------SKRSRAEVLARDNYKCSDCGR-----TVDDGCKLH 193

Query: 227 VHHVIPLSSGGADTTDNCVALCPNCH 252
           VHH IP S GG +  +N +  C +C+
Sbjct: 194 VHHKIPASHGGQNNLENLITNCADCN 219


>UniRef50_C5RG47 HNH endonuclease n=1 Tax=Clostridium cellulovorans 743B
           RepID=C5RG47_CLOCL
          Length = 396

 Score =  101 bits (252), Expect = 2e-20,   Method: Composition-based stats.
 Identities = 30/137 (21%), Positives = 53/137 (38%), Gaps = 6/137 (4%)

Query: 144 ELSELSQPTDDESLLNMRVS-KLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQ 202
           EL EL      ++   +R    L+ + +  PE   +    +     Y R+   +   ++ 
Sbjct: 260 ELEELWSSFSGKTTEIIRTKVDLLAEEVINPERYIEGSTRQIYVNAYERNKKARNKCIEI 319

Query: 203 SKGICENCGKN-APFYLNDGNPYLEVHHVIPLS----SGGADTTDNCVALCPNCHRELHY 257
               C  CG N    Y      ++ VHH+ P+S        D   + V +CPNCH  +H 
Sbjct: 320 YGYNCSVCGVNLEEIYGEIAKEFIHVHHIKPISSINQEYEIDPETDLVPICPNCHAVIHR 379

Query: 258 SKNAKELIEMLYVNINR 274
                 + E+  +  N+
Sbjct: 380 RNQDISISELKDIIKNK 396


>UniRef50_B4S2Y7 HNH nuclease n=2 Tax=Proteobacteria RepID=B4S2Y7_ALTMD
          Length = 116

 Score =  101 bits (251), Expect = 3e-20,   Method: Composition-based stats.
 Identities = 39/110 (35%), Positives = 60/110 (54%), Gaps = 1/110 (0%)

Query: 150 QPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICEN 209
               ++ ++  +     ++     +  + P        V  R+P V A +L ++KGIC +
Sbjct: 7   DKDFEKDVVRAQQRSAEERQRRLQKAPKIPQTSIVEVSVLQRNPDVVAEVLFRAKGICGS 66

Query: 210 CGKNAPF-YLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258
           C   APF    DG+PYLEVHH+  L+ GG DT +N +ALCPNCHR+ H+ 
Sbjct: 67  CKNPAPFSRRKDGSPYLEVHHIQQLAHGGEDTLENAIALCPNCHRQKHFG 116


>UniRef50_B3EB35 HNH endonuclease n=1 Tax=Geobacter lovleyi SZ RepID=B3EB35_GEOLS
          Length = 281

 Score =  101 bits (251), Expect = 3e-20,   Method: Composition-based stats.
 Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 5/100 (5%)

Query: 173 PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVI 231
             G  +   ++ +   Y R P+ +A  +     +C  CG +    Y   G  Y+EVHH I
Sbjct: 173 EGGLPEGACIKVIVNKYERSPVNRAVCIAVYGTVCHVCGFDFGKVYGQIGKGYIEVHHRI 232

Query: 232 PLSSGG----ADTTDNCVALCPNCHRELHYSKNAKELIEM 267
           P+S  G     D   + V LC NCH  +H +    EL  +
Sbjct: 233 PVSKMGASYVIDPIRDLVPLCSNCHSAVHRTDPPVELEAL 272


>UniRef50_A6VSV6 HNH endonuclease n=1 Tax=Marinomonas sp. MWYL1 RepID=A6VSV6_MARMS
          Length = 240

 Score =  101 bits (250), Expect = 3e-20,   Method: Composition-based stats.
 Identities = 44/124 (35%), Positives = 64/124 (51%), Gaps = 2/124 (1%)

Query: 137 WASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQ-PEGSRKPVEVERLQKVYVRDPMV 195
           + + I    +  S        +   + +   + L +     + P  +     VY R+P V
Sbjct: 117 YRTFIEQNNTAESYYYQLSQEVEASLKRGSPERLERINNAPKIPNTITVSATVYQRNPDV 176

Query: 196 KAWILQQSKGICENCGKNAPF-YLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254
               L+++ G+CE CGK APF    DG+PYLEVHH+  L+  G DT +N  ALCPNCHRE
Sbjct: 177 ITETLERAAGVCERCGKGAPFIRSKDGSPYLEVHHIQRLADNGPDTLENTKALCPNCHRE 236

Query: 255 LHYS 258
           LH+ 
Sbjct: 237 LHFG 240


>UniRef50_C6MKA5 HNH endonuclease n=1 Tax=Geobacter sp. M18 RepID=C6MKA5_9DELT
          Length = 254

 Score = 99.5 bits (246), Expect = 1e-19,   Method: Composition-based stats.
 Identities = 30/133 (22%), Positives = 52/133 (39%), Gaps = 5/133 (3%)

Query: 146 SELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKG 205
            +       E    + V  +  + +       +    +   K Y R+P+ +   ++    
Sbjct: 119 KKYQVSFASEVTEAVLVKAIEAEEIEDKGPRFEGGVQQYFGKRYERNPVNRLEAIRYHGL 178

Query: 206 ICENCGKN-APFYLNDGNPYLEVHHVIPLS----SGGADTTDNCVALCPNCHRELHYSKN 260
           +C  CG N    Y   G+ Y+EVHHV P+S        D   + + +C NCHR +H + N
Sbjct: 179 VCNVCGFNFEEVYGERGSGYIEVHHVEPISTYDGEQPVDPKTDLITVCSNCHRMIHRNPN 238

Query: 261 AKELIEMLYVNIN 273
               I+     I 
Sbjct: 239 DVLTIQQAQAIIR 251


>UniRef50_UPI0001BC350E HNH endonuclease n=1 Tax=Butyrivibrio crossotus DSM 2876
           RepID=UPI0001BC350E
          Length = 263

 Score = 99.5 bits (246), Expect = 1e-19,   Method: Composition-based stats.
 Identities = 35/164 (21%), Positives = 55/164 (33%), Gaps = 20/164 (12%)

Query: 131 IYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPV---------- 180
           ++ DS   S I     +  +       +  +    I K   + + S  PV          
Sbjct: 91  VFEDSITKSDILKIWKDFKKFNSVAQNVPEKYMDAINKLCEEKKKSHIPVLESNESFVIN 150

Query: 181 -----EVERLQKVYVRDPMVKAWILQQSKGICENCGKNA-PFYLNDGNPYLEVHHVIPL- 233
                 +E     Y R    +   ++     C+ CG +    Y   G  Y+EVHH  PL 
Sbjct: 151 KAEGNRIEFYTTRYERVAKYREAAIKIHGTKCQICGFDFNKKYGYIGENYIEVHHKKPLF 210

Query: 234 ---SSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINR 274
                   +   + + +C NCHR +H  KN     E L   I  
Sbjct: 211 SLDEELIPNPETDMITICSNCHRMIHRKKNDIITPEKLKDAIRE 254


>UniRef50_A0YCZ6 Putative uncharacterized protein n=1 Tax=marine gamma
           proteobacterium HTCC2143 RepID=A0YCZ6_9GAMM
          Length = 267

 Score = 99.1 bits (245), Expect = 1e-19,   Method: Composition-based stats.
 Identities = 32/130 (24%), Positives = 57/130 (43%), Gaps = 9/130 (6%)

Query: 153 DDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGK 212
           +    + +  +  + K  S  EG+ K + V      Y R+P  +   +++    C  C  
Sbjct: 142 ERTGAVEISYADEVPKDNSLKEGAAKKIWVN----AYERNPDARERCIRKWGLNCVVCNF 197

Query: 213 NAP-FYLNDGNPYLEVHHVIPLSS----GGADTTDNCVALCPNCHRELHYSKNAKELIEM 267
           +    Y + G  Y+ VHH+ PL+        +  ++   +CPNCH  LH +KN+   IE 
Sbjct: 198 HFEQCYGHLGKRYIHVHHLKPLAEIQKEYEVNPEEDLRPVCPNCHSMLHRNKNSVLSIEE 257

Query: 268 LYVNINRLQK 277
           L   +N   +
Sbjct: 258 LQTLVNMYSR 267


>UniRef50_C3G8U4 HNH endonuclease n=1 Tax=Bacillus thuringiensis serovar
           andalousiensis BGSC 4AW1 RepID=C3G8U4_BACTU
          Length = 258

 Score = 99.1 bits (245), Expect = 1e-19,   Method: Composition-based stats.
 Identities = 47/250 (18%), Positives = 88/250 (35%), Gaps = 24/250 (9%)

Query: 32  GPGDRNKDYNIALDYIIERLVDSGVSQVVVYLASSSVRKHMHSLDERKIHPGEYFTLIGN 91
                N +    + YI        +    +    +   ++++  DE  +   +Y      
Sbjct: 26  WSQSANHEIGDII-YIYCSAFIGKIKFKCIVEDVNIPWENVNDEDEFWMEKEDY----QK 80

Query: 92  SPRDIRLKMCGYQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSELSQP 151
           +     +++C  Q   S     +    N     +     + S        + +L    + 
Sbjct: 81  AKTKRFMRLCLQQQIESDDLALKKLRENGLLGNIQGPMKLES--------KVDLLTYIER 132

Query: 152 TDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCG 211
             +  +        + + LS  EG+RK V V +    Y R  + +   ++     C  C 
Sbjct: 133 CFNNDISKSVYPDEVPEQLSIMEGNRKTVVVNQ----YERSAVARRKCIEHHGCYCHVCH 188

Query: 212 KNAPF-YLNDGNPYLEVHHVIPLSSGGA----DTTDNCVALCPNCHRELHYSKNAKEL-- 264
            +    Y + G  ++ VHH IPLS  G     D  ++ + +CPNCH  LH          
Sbjct: 189 LDFKKQYGSLGKGFIHVHHKIPLSEIGDEYEVDYVNDLIPVCPNCHAMLHRKSMNGSFLT 248

Query: 265 IEMLYVNINR 274
           IE L V +N+
Sbjct: 249 IEELKVLMNK 258


>UniRef50_B5G9G0 HNH endonuclease n=1 Tax=Streptomyces sp. SPB74 RepID=B5G9G0_9ACTO
          Length = 272

 Score = 99.1 bits (245), Expect = 2e-19,   Method: Composition-based stats.
 Identities = 42/202 (20%), Positives = 74/202 (36%), Gaps = 16/202 (7%)

Query: 81  HPGEYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASI 140
           +P E  +    +     LK     A F    + +  +G +  R       +  D      
Sbjct: 59  YPPEQRSAEYRNRNGAALKTHNI-ASFHPDYQGKPTNGGQLDR------EVLQDFLERPA 111

Query: 141 IRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAW-- 198
              + +EL +       L         +      G+ +   + R  +   R+  ++    
Sbjct: 112 EMAQAAELIRAGLRSGELQPAPLNED-EDQDDDVGAPEGRVLYRRHRTRERNKGLRKKKI 170

Query: 199 --ILQQSKGI-CENCGKN-APFYLNDGNPYLEVHHVIPLSS--GGADTTDNCVALCPNCH 252
             +L+Q   + CE CG +   FY   G+ Y+E HHV+PL     G     +   +C NCH
Sbjct: 171 ASVLKQGGALSCEACGFDFGKFYGERGDGYIECHHVVPLHEAGEGTTRLADLALICSNCH 230

Query: 253 RELHYSKNAKELIEMLYVNINR 274
           R +H S       E+  V ++R
Sbjct: 231 RMIHRSAPWPTPAELRLVVLDR 252


>UniRef50_UPI0001BC7B91 HNH endonuclease n=1 Tax=Bacteroides sp. D2 RepID=UPI0001BC7B91
          Length = 235

 Score = 98.7 bits (244), Expect = 2e-19,   Method: Composition-based stats.
 Identities = 27/109 (24%), Positives = 46/109 (42%), Gaps = 6/109 (5%)

Query: 172 QPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAP-FYLNDGNPYLEVHHV 230
           +     +    +     + R+  ++   L+     C+ CG N    Y   G  Y+EVHH+
Sbjct: 126 EEAALTEGKLHQVSLTKHERNQALRQLCLKHYGYTCQVCGMNFEAVYGKLGKNYIEVHHI 185

Query: 231 IPLSS-GGADTTD---NCVALCPNCHRELHYSKNAKELI-EMLYVNINR 274
            P++   G    D     + LC NCH  +H  KN + L  E L   +++
Sbjct: 186 NPIAETDGEHVLDPKTGLIPLCSNCHSMIHRGKNGRVLTPEELKAILHQ 234


>UniRef50_C3C627 Restriction endonuclease n=7 Tax=Bacillus RepID=C3C627_BACTU
          Length = 333

 Score = 98.7 bits (244), Expect = 2e-19,   Method: Composition-based stats.
 Identities = 44/130 (33%), Positives = 65/130 (50%), Gaps = 2/130 (1%)

Query: 140 IIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKV--YVRDPMVKA 197
           I  G +   +     +   N +  KL  + L +      P   +R  K   Y R+  V  
Sbjct: 191 IRDGIILPQNIVLSKQVKENKKARKLDYQKLKERAKKATPSSNKRYTKTETYQRNEFVAE 250

Query: 198 WILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHY 257
           +  +++ GICE C + APF   +GNPYLE HHV  LS GG DT  N V +C NCHR LH 
Sbjct: 251 FSKRRANGICELCEQQAPFEDKEGNPYLESHHVEWLSEGGEDTIYNTVGVCANCHRRLHV 310

Query: 258 SKNAKELIEM 267
             +  +++++
Sbjct: 311 LNDENDVMKL 320


>UniRef50_C1SP87 Predicted restriction endonuclease n=1 Tax=Denitrovibrio
           acetiphilus DSM 12809 RepID=C1SP87_9BACT
          Length = 244

 Score = 98.3 bits (243), Expect = 2e-19,   Method: Composition-based stats.
 Identities = 28/128 (21%), Positives = 43/128 (33%), Gaps = 6/128 (4%)

Query: 155 ESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNA 214
                 +        +S  +   +  +      +Y RD   +   L+     C  CG N 
Sbjct: 118 ADKFKAQHVYYYPDEISDSQKIYEGAKTTVTVNIYERDHDARTKCLESQGCTCSVCGFNF 177

Query: 215 P-FYLNDGNPYLEVHHVIPLSS----GGADTTDNCVALCPNCHRELHYSKNAKELIEMLY 269
              Y   G  ++  HH+ P S        D   + V LCPNCH  +H       + E L 
Sbjct: 178 EQAYGLMGIDFIHTHHITPPSEIDKNYIPDPAKDLVPLCPNCHAMIHRKSPPYTI-EQLR 236

Query: 270 VNINRLQK 277
             + R  K
Sbjct: 237 AKLRRKVK 244


>UniRef50_C3IFK0 5-methylcytosine-specific restriction enzyme A n=5 Tax=Bacteria
           RepID=C3IFK0_BACTU
          Length = 260

 Score = 98.3 bits (243), Expect = 3e-19,   Method: Composition-based stats.
 Identities = 36/166 (21%), Positives = 62/166 (37%), Gaps = 10/166 (6%)

Query: 119 NRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKL-----IKKTLSQP 173
           N   RI I       + F+     G++ E         L  + +        + + +  P
Sbjct: 92  NPKGRIYIFTRESNENIFFTYRGTGDVKEYDDTKPVRILWKINIENEMNLLKLPEKIIDP 151

Query: 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIP 232
           E   +    +    VY R+ + +   ++     C  CG N    Y + G  ++ VHH+I 
Sbjct: 152 EKYIEGATKQINVNVYERNSVARMKCIEHYGVNCIICGFNFEEIYGSVGKEFIHVHHLIE 211

Query: 233 L----SSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINR 274
           L         D  ++   +CPNCH  LH  K A  + EM  +   +
Sbjct: 212 LREINEQYEVDPIEDLRPVCPNCHAILHKRKPAYSIKEMKSIIRKK 257


>UniRef50_B1QVB2 HNH endonuclease domain protein n=2 Tax=Clostridium butyricum
           RepID=B1QVB2_CLOBU
          Length = 409

 Score = 98.0 bits (242), Expect = 3e-19,   Method: Composition-based stats.
 Identities = 28/137 (20%), Positives = 46/137 (33%), Gaps = 6/137 (4%)

Query: 146 SELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKG 205
           +       +       +S+  +      E   +          Y R+P  +   L+    
Sbjct: 270 NHAYFTISEMYSKKEIISRYNENDGKSDEKYTEGAMTTIQVNKYERNPKARKKCLEYYGY 329

Query: 206 ICENCGKN-APFYLNDGNPYLEVHHVIPLSS----GGADTTDNCVALCPNCHRELHYSKN 260
            C  CG +   FY   G   +EVHH   L+        D   +   +C NCH  +H  K 
Sbjct: 330 KCCICGFDFEKFYGYIGKNIIEVHHKKALNEIKNTYEVDPIKDLRPVCSNCHTIIHNRKP 389

Query: 261 AKELIEMLYVNINRLQK 277
             E+ E L   I +  +
Sbjct: 390 DYEI-EELKSIITQKHE 405


>UniRef50_D2QLF4 HNH endonuclease n=1 Tax=Spirosoma linguale DSM 74
           RepID=D2QLF4_9SPHI
          Length = 367

 Score = 98.0 bits (242), Expect = 3e-19,   Method: Composition-based stats.
 Identities = 32/129 (24%), Positives = 53/129 (41%), Gaps = 10/129 (7%)

Query: 152 TDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCG 211
           + D   +     + +  T +  EG+ K + V R    Y RD   +   +      C+ C 
Sbjct: 224 SRDPEKVPFHYPEEVPSTKTYVEGAVKQITVNR----YERDQDARTDCINHYGAKCQACE 279

Query: 212 KN-APFYLNDGNPYLEVHHVIPLSSGGA----DTTDNCVALCPNCHRELHYSKNAKELIE 266
            +    Y N G  Y+ VHH+ P +        D   + + +CPNCH  LH  K   ++ +
Sbjct: 280 FDFEEIYGNIGKGYIHVHHIKPFNEIKTSYRVDPIKDLIPVCPNCHAMLHTGKEVMDIAD 339

Query: 267 MLYVNINRL 275
            L   I +L
Sbjct: 340 -LKALIMQL 347


>UniRef50_A9F818 Putative restriction endonuclease n=1 Tax=Phaeobacter gallaeciensis
           2.10 RepID=A9F818_9RHOB
          Length = 220

 Score = 97.6 bits (241), Expect = 4e-19,   Method: Composition-based stats.
 Identities = 33/88 (37%), Positives = 45/88 (51%), Gaps = 1/88 (1%)

Query: 175 GSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLS 234
            S K         V+VR+      + Q + G+C+ C     F    G+ +LEVHH   LS
Sbjct: 133 KSAKAEVNSVTGTVFVRNSEFSRRVRQAANGVCDACKGK-TFQTQSGDWFLEVHHKKWLS 191

Query: 235 SGGADTTDNCVALCPNCHRELHYSKNAK 262
            GG DT +N VALCPNCHR+ H+    +
Sbjct: 192 EGGTDTIENMVALCPNCHRQEHFGSTRR 219


>UniRef50_Q1L9I8 HNH nuclease n=2 Tax=cellular organisms RepID=Q1L9I8_RALME
          Length = 348

 Score = 97.2 bits (240), Expect = 5e-19,   Method: Composition-based stats.
 Identities = 57/249 (22%), Positives = 96/249 (38%), Gaps = 29/249 (11%)

Query: 37  NKDYNIALDYIIERLVDSGVSQVVVYLASSSVRKHMHSLDERKIHPGEYFTLIGNSPRDI 96
           + D+++ L  I +R ++SGV+  ++      ++      D   + P      I  +  + 
Sbjct: 112 DDDWDLTLSEIRDRAMESGVTHFLL------LQPRGDGFDFAALLPVADVPRIWRAQCET 165

Query: 97  RLKMCGY-------QAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSELS 149
              +          + +    G   +   +        VP    D  W+     +L  L 
Sbjct: 166 SESLIATGKLGRIRKNHAKNGGSPTLYLKDTRTPDAHAVP----DVLWSWPGVSDLCSL- 220

Query: 150 QPTDDESLLNMRVSKLIKKTLSQPE--GSRKPVEVERLQKVYVRDPMVKAWILQQSKGIC 207
           Q    ES        L       P   GS  P      +    RD  V+  +L ++ G+C
Sbjct: 221 QEVGGESPFGPIDDTLDDLQAPSPAAAGSDSPERRTAERSYVKRDDRVRRQVLDRADGVC 280

Query: 208 EN--CGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELI 265
           EN  C   APF       +L+VHH+  + +  +D   NCVA+CPNCHR  HY+ +   + 
Sbjct: 281 ENPTCSIRAPF-----PSFLDVHHIFGVET--SDRAWNCVAICPNCHRAAHYAPDRSAIN 333

Query: 266 EMLYVNINR 274
           E L    +R
Sbjct: 334 EELLRVASR 342


>UniRef50_C9ADX3 5-methylcytosine-specific restriction enzyme A n=2 Tax=Enterococcus
           faecium RepID=C9ADX3_ENTFC
          Length = 253

 Score = 97.2 bits (240), Expect = 5e-19,   Method: Composition-based stats.
 Identities = 26/116 (22%), Positives = 45/116 (38%), Gaps = 5/116 (4%)

Query: 156 SLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-A 214
            ++       +K+   + +   +  ++ R   +Y RDP  +   L      C  C  N  
Sbjct: 127 KMIPSMDQATVKEQTLKRKKFLEGRKINRYVNIYERDPRARKACLGHYGYRCVVCKFNFE 186

Query: 215 PFYLNDGNPYLEVHHVIPLSS----GGADTTDNCVALCPNCHRELHYSKNAKELIE 266
             Y   G  ++ VHH   LS        D  ++   +CPNCH  +H  + A  + E
Sbjct: 187 ETYGEIGKEFIHVHHEKELSMLDEFYEIDPIEDMKPVCPNCHAMIHRKRPAYTIEE 242


>UniRef50_UPI0001A457FB putative 5-methylcytosine-specific restriction enzyme A n=1
           Tax=Neisseria subflava NJ9703 RepID=UPI0001A457FB
          Length = 255

 Score = 97.2 bits (240), Expect = 6e-19,   Method: Composition-based stats.
 Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 5/111 (4%)

Query: 167 KKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYL 225
              ++     ++    + +   Y RDP  +   L++    C  C  N   FY   G  ++
Sbjct: 139 PDEVNHQSEYQEGSVQQVMVNRYERDPKAREACLKKYGYNCSVCNFNFEDFYGEIGKNFI 198

Query: 226 EVHHVIPLSSGGA---DTTDNCVALCPNCHRELHYSKNAKELIEMLYVNIN 273
            VHH+ P+S+ G    +   +   +CPNCH  LH   N  + IE L + I 
Sbjct: 199 HVHHLTPVSNNGERYTNPEKDLRPVCPNCHAMLH-KTNRPQRIEDLKLLIK 248


>UniRef50_B1ZMM6 HNH endonuclease n=1 Tax=Opitutus terrae PB90-1 RepID=B1ZMM6_OPITP
          Length = 279

 Score = 96.4 bits (238), Expect = 9e-19,   Method: Composition-based stats.
 Identities = 45/215 (20%), Positives = 84/215 (39%), Gaps = 9/215 (4%)

Query: 62  YLASSSVRKHMHSLDERKIHPGEYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEIPSGNRT 121
           Y+  +  R     L +R++    Y+  +      +       +  F    R  I +   +
Sbjct: 69  YVKVAPFRDVHWELSKRRLGLKSYYVRVQWDAMVLPEFGLSRRRLFRGVLRSSIVNAQAS 128

Query: 122 KRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVE 181
              L        +S W   +      + +              L    +     +++   
Sbjct: 129 GCRLTEKEASKLESVWQEHLNLASKNVGRSVVRALPTEDTFDDLDPSGIGSDGAAKQKHI 188

Query: 182 VERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTT 241
           V  +     R+P V+ W+L++S+G+CE  G +          +L+VHH++  + G  D  
Sbjct: 189 VSGV----KRNPKVRRWVLKRSRGVCERLGCHIT---RSFAGFLDVHHILGAAKG--DRV 239

Query: 242 DNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQ 276
            NCVALCPNCHRE H + N K++ + L     + +
Sbjct: 240 WNCVALCPNCHRETHCAPNRKKINKELLRFAKQFR 274


>UniRef50_B3CDE4 Putative uncharacterized protein n=1 Tax=Bacteroides intestinalis
           DSM 17393 RepID=B3CDE4_9BACE
          Length = 261

 Score = 96.4 bits (238), Expect = 9e-19,   Method: Composition-based stats.
 Identities = 31/109 (28%), Positives = 52/109 (47%), Gaps = 6/109 (5%)

Query: 167 KKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNA-PFYLNDGNPYL 225
           K+     E   +    + L   Y R+P+ +   +++   IC+ CG +    Y   GN ++
Sbjct: 151 KQNKIYTEEYYEGSLQQALVNRYERNPIARKKCIEKHGCICQVCGMDFSKVYGELGNGFI 210

Query: 226 EVHHVIPLS--SGGAD--TTDN-CVALCPNCHRELHYSKNAKELIEMLY 269
            VHH++P+S   G A     +N  V +CPNCH  LH  K + E +  + 
Sbjct: 211 HVHHIVPISALKGEAHKIEPENGLVPVCPNCHAMLHKGKLSIEELRKIL 259


>UniRef50_Q1QEV2 HNH endonuclease n=5 Tax=Gammaproteobacteria RepID=Q1QEV2_PSYCK
          Length = 282

 Score = 96.4 bits (238), Expect = 9e-19,   Method: Composition-based stats.
 Identities = 44/130 (33%), Positives = 66/130 (50%), Gaps = 8/130 (6%)

Query: 147 ELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGI 206
            +++P+  +SL  +R   L                 E++Q +  R   +K +  +++ GI
Sbjct: 156 YVTKPSKGKSLQQLREIALS-------STPTHASTQEKIQSIQNRSTAIKLYAKKRANGI 208

Query: 207 CENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIE 266
           CE C + APF    G PYLEVHH+  L+ GGAD   N +ALCP CHR+ HYS N  E   
Sbjct: 209 CEGCNEIAPFETKSG-PYLEVHHLTRLADGGADLPQNVIALCPTCHRKAHYSLNHLEFNN 267

Query: 267 MLYVNINRLQ 276
            L   +  ++
Sbjct: 268 QLINKVAAIE 277


>UniRef50_A9B4I7 HNH endonuclease n=1 Tax=Herpetosiphon aurantiacus ATCC 23779
           RepID=A9B4I7_HERA2
          Length = 224

 Score = 96.0 bits (237), Expect = 1e-18,   Method: Composition-based stats.
 Identities = 30/138 (21%), Positives = 48/138 (34%), Gaps = 6/138 (4%)

Query: 143 GELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSR-KPVEVERLQKVYVRDPMVKAWILQ 201
              S+                +L  +          +  +V+ L   Y R+   +   + 
Sbjct: 87  KYCSDCKPAKSVLEQFLFYPDELDSQVELDSRAELWEGAKVQVLVNQYERNAQARQRGIA 146

Query: 202 QSKGICENCGKNA-PFYLNDGNPYLEVHHVIPLSS----GGADTTDNCVALCPNCHRELH 256
           Q    C  C  +    Y   G  ++ VHH+ PL+S       D  ++   +CPNCH  LH
Sbjct: 147 QYGTRCLVCELDFVERYGPIGEGFIHVHHIKPLASINAGYQVDPINDLRPVCPNCHAMLH 206

Query: 257 YSKNAKELIEMLYVNINR 274
             K     IE L   + R
Sbjct: 207 RGKEQPLTIEELRALLKR 224


>UniRef50_B9DID5 Putative uncharacterized protein n=1 Tax=Staphylococcus carnosus
           subsp. carnosus TM300 RepID=B9DID5_STACT
          Length = 242

 Score = 96.0 bits (237), Expect = 1e-18,   Method: Composition-based stats.
 Identities = 33/120 (27%), Positives = 50/120 (41%), Gaps = 9/120 (7%)

Query: 144 ELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQS 203
            LSE  +    ES ++  +   I K     EG +K V V +    Y R+P  +   +   
Sbjct: 122 RLSEKLKSYLLESEIHYVLYPEIIKDEELYEGIKKQVIVNK----YERNPKARQICVNYY 177

Query: 204 KGICENCGKN-APFYLNDGNPYLEVHHVIPLSS----GGADTTDNCVALCPNCHRELHYS 258
              C+ C  N    Y   G  ++ VHH++PLS        D   +   +CPNCH  +H  
Sbjct: 178 GYNCKVCDLNFEKEYGEIGKNFIHVHHIVPLSKIDEQYKIDPIKDLRPVCPNCHAMIHRG 237


>UniRef50_Q67M53 Conserved domain protein n=1 Tax=Symbiobacterium thermophilum
           RepID=Q67M53_SYMTH
          Length = 270

 Score = 96.0 bits (237), Expect = 1e-18,   Method: Composition-based stats.
 Identities = 28/99 (28%), Positives = 42/99 (42%), Gaps = 6/99 (6%)

Query: 182 VERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSSGG--- 237
           VE   + Y RDP  +   ++     C  CG N    Y   G  ++EVHHV PL +     
Sbjct: 159 VEYYGRRYERDPENRRRAIEIHGLNCVVCGFNFEEVYGPRGRDFIEVHHVKPLKAFEGVA 218

Query: 238 --ADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINR 274
              D   + V +C NCHR +H   ++    + L   +  
Sbjct: 219 QVVDPKVDLVPICANCHRMIHRRHDSVLTPDQLRRIVEE 257


>UniRef50_C4UQ38 Putative uncharacterized protein n=1 Tax=Yersinia rohdei ATCC 43380
           RepID=C4UQ38_YERRO
          Length = 206

 Score = 96.0 bits (237), Expect = 1e-18,   Method: Composition-based stats.
 Identities = 38/170 (22%), Positives = 63/170 (37%), Gaps = 12/170 (7%)

Query: 112 RKEIPSGNRTKRILINVPG-IYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTL 170
           R  I S     R++  + G  Y+DSF ++        LS    + S  +     L     
Sbjct: 42  RTTISSNEEITRLISKMSGGYYADSFVSNCSTAMRRYLSFVNSELSYFHYPDEILNHSEY 101

Query: 171 SQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHH 229
                  +  + + +   Y RD   +   ++     C  C  N    Y   G  ++ VHH
Sbjct: 102 I------EGAKKQIIVNSYERDRDARNKAIEIHGLNCSVCDMNFEDVYGEIGVGFIHVHH 155

Query: 230 VIPLSS----GGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRL 275
           + PL         D  D+ + +CPNCH  LH  KN     E+  +   ++
Sbjct: 156 LKPLHEINKEYHVDPEDDLITVCPNCHAMLHRLKNRPSKKELKDLIKKKI 205


>UniRef50_Q0AUW7 Hnh endonuclease n=1 Tax=Syntrophomonas wolfei subsp. wolfei str.
           Goettingen RepID=Q0AUW7_SYNWW
          Length = 274

 Score = 95.7 bits (236), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 30/121 (24%), Positives = 50/121 (41%), Gaps = 8/121 (6%)

Query: 158 LNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APF 216
           L+  V    +    Q E   +  +++ +   Y R+   +   + +    C  C  +   F
Sbjct: 154 LHGEVQLAQEVDEEQTEKLYEGAKIQIVVNAYERNIKARQICIDKYGYKCSICDFDFEEF 213

Query: 217 YLNDGNPYLEVHHVIPLSSGGA----DTTDNCVALCPNCHRELHYSKNAKELIEMLYVNI 272
           Y   G+ Y+EVHH+IPL         D  ++   +CPNCH  LH +  +    E L   I
Sbjct: 214 YGMLGSDYIEVHHLIPLHEINKEYRVDPINDLRPVCPNCHAMLHRAGISY---EELKNKI 270

Query: 273 N 273
            
Sbjct: 271 E 271


>UniRef50_D1NJY2 Transcriptional regulator, XRE family n=1 Tax=Clostridium
           thermocellum JW20 RepID=D1NJY2_CLOTM
          Length = 446

 Score = 95.3 bits (235), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 39/156 (25%), Positives = 70/156 (44%), Gaps = 12/156 (7%)

Query: 134 DSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEG---SRKPVEVERLQKVYV 190
           + F+  ++  +   +    + +S +  +  K         EG    + PV        ++
Sbjct: 274 EQFYDYLVAKKEGWVDSEHEVDSTMQTQEEKSEDNNFDDEEGPIDRQDPVVDREGNIRFL 333

Query: 191 RDPMVKAWILQQSKGICENCGKNAPFYLND-GNPYLEVHHVIPLSSG-----GADTTDNC 244
           R+P V    L++++  CE    +  F       PY+E HH+IP+S+        D T N 
Sbjct: 334 RNPKVAIQALKKAQYKCEINDAHETFIAKSSNKPYVESHHLIPISNSAMFGFSIDITANI 393

Query: 245 VALCPNCHRELHYSKN--AKELIEMLYVNI-NRLQK 277
            +LCPNCHR +H + +   +E++  LY     RL+K
Sbjct: 394 CSLCPNCHRAIHSATDEVKREMLTKLYEKRKERLEK 429


>UniRef50_D1P9G2 5-methylcytosine-specific restriction enzyme A n=1 Tax=Prevotella
           copri DSM 18205 RepID=D1P9G2_9BACT
          Length = 251

 Score = 95.3 bits (235), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 26/113 (23%), Positives = 51/113 (45%), Gaps = 7/113 (6%)

Query: 172 QPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN--APFYLNDGNPYLEVHH 229
           + E   +   + +   V  R+P ++   L +    C+ CG +    +    G  ++EVHH
Sbjct: 131 REETEGERKHILKETDVIRRNPQLRQMCLDKYGYQCQCCGMDFEETYGKELGVNFMEVHH 190

Query: 230 VIPLSSGGADT-----TDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277
           +  +S+   D       +N V LC NCH  +H+ K+++  +  L      ++K
Sbjct: 191 IRMISTYETDGVPENFLENLVPLCSNCHSMIHHIKDSEHPLRDLREAYRGIKK 243


>UniRef50_C8TQ55 Predicted endonuclease n=10 Tax=Enterobacteriaceae
           RepID=C8TQ55_ECO26
          Length = 216

 Score = 95.3 bits (235), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 28/150 (18%), Positives = 55/150 (36%), Gaps = 6/150 (4%)

Query: 129 PGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKV 188
           P  ++    +  ++  + +      D++        L    L   E   +   ++     
Sbjct: 63  PADFTGGIKSKCVKLLIEQGFHIHLDKAAAAPIADVLFPDELPSQETYLEGAAIKVTVNR 122

Query: 189 YVRDPMVKAWILQQSKGICENCGKNA-PFYLNDGNPYLEVHHVIPLS----SGGADTTDN 243
           Y RD   +   ++     C  CG +    Y +    ++ VHH++PLS        D  ++
Sbjct: 123 YERDKKARDKAVEHHGCQCNVCGVDLVKIYGDIAEGFIHVHHLVPLSAIKEDYQLDPVND 182

Query: 244 CVALCPNCHRELHYSKNAKELIEMLYVNIN 273
            + + PNCH  LH  K      E L   ++
Sbjct: 183 LLPVYPNCHAMLHRRKPPFTP-EQLKALMD 211


>UniRef50_Q8VUW2 Putative uncharacterized protein 5'-methylcytosine-specific
           restiction enxyme A of Methanosarcima mazei n=1
           Tax=Staphylococcus hominis RepID=Q8VUW2_STAHO
          Length = 211

 Score = 94.9 bits (234), Expect = 3e-18,   Method: Composition-based stats.
 Identities = 30/137 (21%), Positives = 54/137 (39%), Gaps = 9/137 (6%)

Query: 142 RGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQ 201
           R   +EL     +         +   + +   EG      +++    + R+  ++   ++
Sbjct: 77  RSLSNELLDFVLEVLEKTSDFDESQIENVEYKEG----KILKKYGSKFERNSKLREKAIE 132

Query: 202 QSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSSGGADTTDN----CVALCPNCHRELH 256
                C+ CG N    Y N G  ++E+HH+ P+     +   N     + LC NCH+ +H
Sbjct: 133 IHGVTCKVCGFNFEKKYGNIGKNFIEIHHIKPMYDIRKEILVNPQTDLIPLCSNCHKMIH 192

Query: 257 YSKNAKELIEMLYVNIN 273
            SK     IE L   I 
Sbjct: 193 RSKRKPYTIEQLKSMIK 209


>UniRef50_A5W5D0 HNH endonuclease n=4 Tax=Gammaproteobacteria RepID=A5W5D0_PSEP1
          Length = 268

 Score = 94.5 bits (233), Expect = 3e-18,   Method: Composition-based stats.
 Identities = 31/156 (19%), Positives = 62/156 (39%), Gaps = 9/156 (5%)

Query: 127 NVPGIYSDSFWASIIRGEL-SELSQPTDDESLLNMRVSKLIKKTLSQP---EGSRKPVEV 182
            +PG  + ++W   +R    S+         LL+ R+   + ++   P   E + +  + 
Sbjct: 105 TIPGSRASNYWRDGVRLISQSDYDAILSHAKLLDPRLDTALPQSEDDPITFESANEGSKT 164

Query: 183 ERLQKVYVRDPMVKAWILQQSKGICENCGKNAP-FYLNDGNPYLEVHHVIPLSSGG---- 237
                 Y R   ++   +      C+ CG +    Y      ++ VHHV+P+S  G    
Sbjct: 165 SYFGTRYERRKDLRMKAIAIHGLDCKACGFDFEQAYGEHAKGFIHVHHVVPISKFGGEQA 224

Query: 238 ADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNIN 273
            +   + V LC NCH  +H  ++    ++ L   + 
Sbjct: 225 VNPETDLVTLCANCHAVVHRKRDMTLSVDELKGMLR 260


>UniRef50_B0KIU7 HNH endonuclease n=1 Tax=Pseudomonas putida GB-1 RepID=B0KIU7_PSEPG
          Length = 281

 Score = 94.5 bits (233), Expect = 3e-18,   Method: Composition-based stats.
 Identities = 30/132 (22%), Positives = 46/132 (34%), Gaps = 6/132 (4%)

Query: 141 IRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWIL 200
           I    S  +        L + V    ++   +  G  +  +V      Y RD   +A  L
Sbjct: 141 IDLWTSRAAAAIFALLPLEVDVDDAEEE-FREVIGLPEGAKVRIEVNRYERDRRNRAAAL 199

Query: 201 QQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSSGG----ADTTDNCVALCPNCHREL 255
                 C+ C  +    Y       +EVHH  P+S  G     D   + + LCPNCH   
Sbjct: 200 AIHGYSCKACDLDMGGRYGPVAAGLIEVHHTTPVSELGLGYIIDPKTDLIPLCPNCHSVS 259

Query: 256 HYSKNAKELIEM 267
           H       + E+
Sbjct: 260 HRRSPPFSVAEL 271


>UniRef50_C9BZK6 Restriction endonuclease (Fragment) n=4 Tax=Firmicutes
           RepID=C9BZK6_ENTFC
          Length = 96

 Score = 94.5 bits (233), Expect = 3e-18,   Method: Composition-based stats.
 Identities = 35/89 (39%), Positives = 51/89 (57%), Gaps = 1/89 (1%)

Query: 186 QKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCV 245
              Y R+P V  ++ + +KGIC+ C +  PF   DG PYL  HH+  LS GG D  +NC+
Sbjct: 1   HHGYKRNPFVSEYVKRLAKGICQLCQEKGPFI-KDGVPYLHCHHIEYLSQGGKDVIENCI 59

Query: 246 ALCPNCHRELHYSKNAKELIEMLYVNINR 274
           ALCPNCH  +H  +   +  ++L +   R
Sbjct: 60  ALCPNCHARIHELELPDDKEKLLKIVEKR 88


>UniRef50_D2S1X8 HNH endonuclease n=1 Tax=Haloterrigena turkmenica DSM 5511
           RepID=D2S1X8_9EURY
          Length = 84

 Score = 93.7 bits (231), Expect = 5e-18,   Method: Composition-based stats.
 Identities = 34/82 (41%), Positives = 49/82 (59%)

Query: 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254
           ++ + LQ + G+C+ C  +APF  +D   +LEVHH+   S+GGAD   N +ALCPNCHR 
Sbjct: 1   MRKYALQVADGVCQGCSDDAPFLTDDRESFLEVHHLRRRSNGGADHPKNVIALCPNCHRR 60

Query: 255 LHYSKNAKELIEMLYVNINRLQ 276
           +H+ +N  E  E L      L 
Sbjct: 61  VHHGRNGDEFNEDLIDKAEELH 82


>UniRef50_B0KGB9 Restriction endonuclease-like protein n=1 Tax=Pseudomonas putida
           GB-1 RepID=B0KGB9_PSEPG
          Length = 314

 Score = 93.7 bits (231), Expect = 6e-18,   Method: Composition-based stats.
 Identities = 22/95 (23%), Positives = 34/95 (35%), Gaps = 5/95 (5%)

Query: 178 KPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPF-YLNDGNPYLEVHHVIPLSSG 236
           +          Y R+P  +   +      C+ CG N    Y       + VHH+ PL++ 
Sbjct: 204 EGAVRTVELTRYERNPTARRLCIAHYGPTCQACGLNYEIKYGPIAVDLIHVHHLTPLAAI 263

Query: 237 GA----DTTDNCVALCPNCHRELHYSKNAKELIEM 267
           G     D   + V LC  CH  +H         E+
Sbjct: 264 GESYQVDPIRDLVPLCATCHHVVHAKTPPYTPEEL 298


>UniRef50_C6J8S5 Putative uncharacterized protein n=1 Tax=Ruminococcus sp.
           5_1_39BFAA RepID=C6J8S5_9FIRM
          Length = 285

 Score = 93.3 bits (230), Expect = 8e-18,   Method: Composition-based stats.
 Identities = 33/195 (16%), Positives = 74/195 (37%), Gaps = 12/195 (6%)

Query: 93  PRDIRLKMCGYQAYFSRTGRKEIPSGNR--TKRILINVP-------GIYSDSFWASIIRG 143
           PR+  L     Q +F      ++   NR    R  I +P        IY+  +  + +  
Sbjct: 80  PRNGELSQALQQYFFKSMSYIKMIRENRDPKDRSYIKMPDGLKEYLAIYTTEYEDTFLLE 139

Query: 144 ELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVE-RLQKVYVRDPMVKAWILQQ 202
            +++       +++  MR   +  +   + E     +E + ++ K+   +  +   +   
Sbjct: 140 PIAQDDFQVMKKAIQGMRERTVENEIEYEMEDKSSGIEKKLQIVKIRKLNRKIGENLKLL 199

Query: 203 SKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAK 262
               C+ CG         G+   E HH+    +   +  +N + +CPN H  +H +    
Sbjct: 200 YGYRCQICG--QVIGEKYGSHIAEAHHIDYFVNSLNNDANNQMIVCPNHHSVIHDANPVF 257

Query: 263 ELIEMLYVNINRLQK 277
           +   M+Y   N +++
Sbjct: 258 DRRRMVYRFDNGVEE 272


>UniRef50_B0A7V0 Putative uncharacterized protein n=1 Tax=Clostridium bartlettii DSM
           16795 RepID=B0A7V0_9CLOT
          Length = 254

 Score = 93.3 bits (230), Expect = 8e-18,   Method: Composition-based stats.
 Identities = 38/221 (17%), Positives = 73/221 (33%), Gaps = 8/221 (3%)

Query: 62  YLASSSVRKHMHSLDERKIHPGEYFTLI---GNSPRDIRLKMCGYQAYFSRTGRKEIPSG 118
           +  S   R+     D   +  GE   LI    N+  +  ++M   Q   +R   K     
Sbjct: 29  HRGSGVPREIRWFFDSENLQNGEQKPLILIYENNEYNAHIEMESSQLSRTRMFWKSDLKK 88

Query: 119 NRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRK 178
                +         ++ + SI   ++   +   +   L  +    +      + E   +
Sbjct: 89  EFDGVLKDYRLKSGKENGYPSIKFTKIFGNTYEVEFIGLDLLNDESINPLETIEIENRVE 148

Query: 179 PVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPL---- 233
               +     Y R    +   ++     C  C  +    Y   G  ++EVHH  PL    
Sbjct: 149 GKRKKIYTTKYERSYKNREKAIKIHGTRCMVCDFDFEEAYGELGKDFIEVHHTKPLYSLE 208

Query: 234 SSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINR 274
                +  ++ V LC NCHR +H  ++    +E L   +  
Sbjct: 209 EEIEINPEEDLVCLCSNCHRMIHRRRDKILTVEELKEIMEE 249


>UniRef50_C6LDW0 Product McrA n=1 Tax=Bryantella formatexigens DSM 14469
           RepID=C6LDW0_9FIRM
          Length = 380

 Score = 93.3 bits (230), Expect = 8e-18,   Method: Composition-based stats.
 Identities = 46/203 (22%), Positives = 72/203 (35%), Gaps = 21/203 (10%)

Query: 93  PRDIRLKMCGYQAYFSRTGRKEIPSGNRTKR--------ILINVPGIYSDSFWASIIRGE 144
               RL   G  A F   G  E+P     K         +   +  +        +I G 
Sbjct: 166 KNSDRLFAVGIPAEFY-QGNYELPQEGLLKHLESPGSVTVKSALKEVSDSVDAGVMITG- 223

Query: 145 LSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSK 204
            +E    +  + L+N     +     +  +      E          +P +    +++S 
Sbjct: 224 -AEAISDSIYQQLVNEADGDISPAEYAAEKYIPPAAERSVSSDRPATNPRLGKAAIKRSG 282

Query: 205 GICENCGK---NAPFYLNDGNPYLEVHHVIPLS-----SGGADTTDNCVALCPNCHRELH 256
             C        +  F   DG PYLEVHH+IPL          DT  N + LCP CHR LH
Sbjct: 283 YKCIFSTDAEPHKTFLKPDGTPYLEVHHLIPLKQQPAFEYKLDTMANLIPLCPLCHRRLH 342

Query: 257 YS--KNAKELIEMLYVNINRLQK 277
           +    +  E++  LY   + + K
Sbjct: 343 HGCRADVDEMLTQLYEERHEILK 365


>UniRef50_A9GYN9 Putative uncharacterized protein n=1 Tax=Roseobacter litoralis Och
           149 RepID=A9GYN9_9RHOB
          Length = 311

 Score = 93.3 bits (230), Expect = 8e-18,   Method: Composition-based stats.
 Identities = 33/148 (22%), Positives = 54/148 (36%), Gaps = 11/148 (7%)

Query: 131 IYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYV 190
             +   W      + SE       + L            L +PE  R+    E       
Sbjct: 159 YPAKVIWGLATNKKGSEFISHRARDGLRKAGFECADLGNLVEPELLREGSIRETTNVRRE 218

Query: 191 RDPMVKAWILQQSKGI------CENCGKN-APFYLNDGNPYLEVHHVIPLSSGGADTTD- 242
           R+P+ +   ++  +        C  CG + A FY   G  ++ VHH+ P+S   A     
Sbjct: 219 RNPVARVLCIEHYRKKNDGRLICIVCGFDFAAFYGTLGEGFIHVHHLNPISEAEASRIVS 278

Query: 243 ---NCVALCPNCHRELHYSKNAKELIEM 267
              + V +CPNCH  +H     + + EM
Sbjct: 279 PEIDLVPVCPNCHSMIHRGGQTRSIAEM 306


>UniRef50_A7I926 HNH endonuclease n=1 Tax=Candidatus Methanoregula boonei 6A8
           RepID=A7I926_METB6
          Length = 266

 Score = 93.3 bits (230), Expect = 9e-18,   Method: Composition-based stats.
 Identities = 32/133 (24%), Positives = 60/133 (45%), Gaps = 14/133 (10%)

Query: 155 ESLLNMRVSKLIKKTLSQ-------PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGIC 207
           ES  ++   ++ K+TL++       PE   +  E E +Q +Y R+  ++   ++     C
Sbjct: 134 ESEWDILSKEIEKRTLTKYEEIFTCPEYFTEGKEREIIQTIYERNSKLREMAIKMHGTTC 193

Query: 208 ENCGKN-APFYLNDGNPYLEVHHVIPLS------SGGADTTDNCVALCPNCHRELHYSKN 260
             CG N A  Y      Y+E+HH++P S          +   + + LC NCHR +H  + 
Sbjct: 194 SVCGFNFAKKYGILSEGYIEIHHLVPHSEHKIKGESEINPETDLIPLCSNCHRIIHKPEK 253

Query: 261 AKELIEMLYVNIN 273
              + E+  +  +
Sbjct: 254 MLSIEELKKIVKS 266


>UniRef50_A0KZG4 HNH endonuclease n=1 Tax=Shewanella sp. ANA-3 RepID=A0KZG4_SHESA
          Length = 253

 Score = 93.0 bits (229), Expect = 1e-17,   Method: Composition-based stats.
 Identities = 33/184 (17%), Positives = 70/184 (38%), Gaps = 15/184 (8%)

Query: 104 QAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVS 163
           + Y  R    E+ +      +L     I+  +   +    +L+ +       + ++   +
Sbjct: 70  RYYLQRF-MSEMTATEFATVLLSVTRHIHYYNAQGAGKHRQLATILAEFQSLAKVHYGQN 128

Query: 164 ---KLIKKTLSQPE---GSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPF- 216
               L+   +S+ E      +         V+ R+P  +   ++     C  CG +    
Sbjct: 129 FNPTLLPSEISEAETGFVFHEGAMKTIELSVHEREPAARRACIEHYGVSCHVCGFDFEHA 188

Query: 217 YLNDGNPYLEVHHVIPLS----SGGADTTDNCVALCPNCHRELHYSKNA---KELIEMLY 269
           Y + G  ++ VHH + L+        +  ++ + +CPNCH  LH    A    +L E+L 
Sbjct: 189 YGDIGKGFIHVHHRVDLALVSNRREVNPIEDLIPVCPNCHAMLHTETPAMAVDKLKELLK 248

Query: 270 VNIN 273
            N+ 
Sbjct: 249 QNLQ 252


>UniRef50_D0IIJ2 HNH endonuclease n=1 Tax=Vibrio sp. RC586 RepID=D0IIJ2_9VIBR
          Length = 244

 Score = 93.0 bits (229), Expect = 1e-17,   Method: Composition-based stats.
 Identities = 25/130 (19%), Positives = 48/130 (36%), Gaps = 6/130 (4%)

Query: 153 DDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGK 212
           +           +        +   +    +     Y R+   +A  ++     C  C  
Sbjct: 115 EFSQKYQTNFQSISYPDELPEDVLIEGARKQITVNAYERNHRARAQCIEHYGNSCYICSF 174

Query: 213 NAPFY-LNDGNPYLEVHHVIPLSSGGA----DTTDNCVALCPNCHRELHYSKNAKELIEM 267
           N   Y  + G  Y+ VHH + L+  G     +  ++   +CPNCH  LH +K A  + E 
Sbjct: 175 NFFEYFGDLGAGYIHVHHQVDLAHVGEAYIVNPIEDLKPVCPNCHAMLHKTKPAMSV-EK 233

Query: 268 LYVNINRLQK 277
           L   ++  ++
Sbjct: 234 LKELVSSRKR 243


>UniRef50_D1BJK4 HNH endonuclease n=1 Tax=Sanguibacter keddieii DSM 10542
           RepID=D1BJK4_SANKS
          Length = 395

 Score = 92.6 bits (228), Expect = 1e-17,   Method: Composition-based stats.
 Identities = 36/106 (33%), Positives = 50/106 (47%), Gaps = 4/106 (3%)

Query: 168 KTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICE--NCGKNAPFYLNDGNPYL 225
           + L+  E + +P  V R+   Y R    +  +L +S G CE   C          G P L
Sbjct: 274 RRLADLERTTEPQTVSRI--AYQRQYAARRAVLIRSAGQCESERCTGMPAELNRKGMPIL 331

Query: 226 EVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVN 271
           +V H++ LS GGAD   N VALCPNCH      ++AK   + L   
Sbjct: 332 DVDHIVELSQGGADHPLNMVALCPNCHAAKTRGQHAKRWEKELRRI 377


>UniRef50_B8KVR3 HNH endonuclease domain protein n=1 Tax=gamma proteobacterium
           NOR51-B RepID=B8KVR3_9GAMM
          Length = 289

 Score = 92.2 bits (227), Expect = 2e-17,   Method: Composition-based stats.
 Identities = 36/156 (23%), Positives = 63/156 (40%), Gaps = 9/156 (5%)

Query: 127 NVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSK-LIKKTLSQPEGSRKPVEVERL 185
           N P  +  S  +++     S+       +    + V   + +K ++ PE +  P E   +
Sbjct: 117 NEPLPFIGSCSSALFDSITSDDDVVKAVQRDFALDVDDDVYQKLVAAPEDAVVPKEYRAM 176

Query: 186 QKVYVRDPMVKAWILQQSKGICENCGKNAPFYLN-DGNPYLEVHHVIPLSSG-----GAD 239
              Y R   V    L+ +   CE    +        G P +EVHH++P+S         D
Sbjct: 177 --RYERSAAVGREALESAGYACEFDNTHETPLSAVTGQPIMEVHHLVPISKSAEFRCSLD 234

Query: 240 TTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRL 275
              N V+LCPNCH  +H S    ++  +  +  +R 
Sbjct: 235 VLANVVSLCPNCHSAIHRSTKTVQVAMLQKLFGDRR 270


>UniRef50_C0CT91 Putative uncharacterized protein n=1 Tax=Clostridium asparagiforme
           DSM 15981 RepID=C0CT91_9CLOT
          Length = 239

 Score = 91.8 bits (226), Expect = 2e-17,   Method: Composition-based stats.
 Identities = 28/102 (27%), Positives = 40/102 (39%), Gaps = 5/102 (4%)

Query: 177 RKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAP-FYLNDGNPYLEVHHVIPL-- 233
            +   V      Y R+   +   +Q     C+ CG +    Y   G  ++E+HH  PL  
Sbjct: 137 SEGERVFFYGTKYERNKKNREMAIQYHGCKCKACGFDFEAVYGEMGKGFIEIHHTKPLYS 196

Query: 234 --SSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNIN 273
                  D   + V +C NCHR LH +K     IE L   I 
Sbjct: 197 LQEEIVIDYRTDLVPVCSNCHRILHRNKEKMLSIEELKQLIQ 238


>UniRef50_A0JWW4 HNH endonuclease n=1 Tax=Arthrobacter sp. FB24 RepID=A0JWW4_ARTS2
          Length = 297

 Score = 91.8 bits (226), Expect = 2e-17,   Method: Composition-based stats.
 Identities = 32/142 (22%), Positives = 48/142 (33%), Gaps = 6/142 (4%)

Query: 137 WASIIRGELSELSQPTDDESLLNMR-VSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMV 195
           W  +  G+  E S       L  +     L   TL  P         +     Y R+P  
Sbjct: 117 WNRVRNGQAIEPSAQARIRDLWRLEGPPPLSGSTLPVPGTYPAWAVSKVEVNRYERNPEA 176

Query: 196 KAWILQQSKGICENCGKNAPF-YLNDGNPYLEVHHVIPL----SSGGADTTDNCVALCPN 250
           +   +      C  CG +    Y + G  +++VHH  P+    SS   D   + V LC N
Sbjct: 177 RRACIAHYGTSCAACGFSFEIAYGDAGREFIDVHHTTPVSLLDSSYRLDPVTDLVPLCSN 236

Query: 251 CHRELHYSKNAKELIEMLYVNI 272
           CH   H        +  L   +
Sbjct: 237 CHAMAHLGVTTPRTLPELRRML 258


>UniRef50_O83027 Disrupted by IS8301 insertion n=1 Tax=Deinococcus radiodurans
           RepID=O83027_DEIRA
          Length = 241

 Score = 91.8 bits (226), Expect = 2e-17,   Method: Composition-based stats.
 Identities = 21/114 (18%), Positives = 42/114 (36%), Gaps = 5/114 (4%)

Query: 159 NMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAP-FY 217
               ++    +  +     +    +     Y R+   +A  +     +C  C  +    Y
Sbjct: 119 ESLDNEAEGVSAEEARTFVEGATRQIFVNAYERNAGARAACIAHFGTVCRVCETDLVAIY 178

Query: 218 LNDGNPYLEVHHVIPLSSGG----ADTTDNCVALCPNCHRELHYSKNAKELIEM 267
                 Y++VHH+  L+  G     +   + + +CPNCH  LH  + A    E+
Sbjct: 179 GEVARGYIQVHHLRSLAEVGRQYEVNPLTDLIPVCPNCHAMLHQRRPAYTPEEL 232


>UniRef50_A3WCW2 HNH endonuclease n=1 Tax=Erythrobacter sp. NAP1 RepID=A3WCW2_9SPHN
          Length = 207

 Score = 91.8 bits (226), Expect = 2e-17,   Method: Composition-based stats.
 Identities = 35/188 (18%), Positives = 66/188 (35%), Gaps = 21/188 (11%)

Query: 91  NSPRDIRLKMCGYQAY---FSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSE 147
            +     +KM  +++    F   G+  + SG + ++++          ++  +      +
Sbjct: 18  RNRNGAYMKMMNFRSIDPAFKAQGKAGMKSGGKLEKVV----------WYKFVKDPVALK 67

Query: 148 LSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAW----ILQQS 203
           L      +++    V  L            +   V RL K Y RD  +         +  
Sbjct: 68  LEADRIRKAVEKADVESLAALPNEDEVEGEEGGVVMRLHKRYERDRSLSRKKIVSAKKAG 127

Query: 204 KGICENCGKNAPFY-LNDGNPYLEVHHVIPLS---SGGADTTDNCVALCPNCHRELHYSK 259
              CE C  +        G+ ++EVHH+ P+     G      +   LC NCHR  H  +
Sbjct: 128 SVECEVCEFDFEAAFGELGDGFIEVHHLKPVHTLGKGSKTRLKDLALLCANCHRMAHRKR 187

Query: 260 NAKELIEM 267
               L E+
Sbjct: 188 IPLSLDEL 195


>UniRef50_D2YGR3 Putative uncharacterized protein n=1 Tax=Vibrio mimicus VM603
           RepID=D2YGR3_VIBMI
          Length = 262

 Score = 91.8 bits (226), Expect = 2e-17,   Method: Composition-based stats.
 Identities = 23/103 (22%), Positives = 38/103 (36%), Gaps = 5/103 (4%)

Query: 177 RKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSS 235
           ++      +     R+P  +   ++     C  C  N    Y   G  ++ VHH   L+S
Sbjct: 159 KEGARFSVMSTAIERNPAARKKCIEHYGYTCAACDINMESKYGRIGKKFIHVHHRTDLAS 218

Query: 236 GG----ADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINR 274
                  D   + + LCPNCH  +H  K A  L  +  +    
Sbjct: 219 IQGIHRVDPLRDLIPLCPNCHAMIHKEKPAMPLENLRAILREH 261


>UniRef50_A3U4A6 E14 prophage-like protein n=1 Tax=Oceanicola batsensis HTCC2597
           RepID=A3U4A6_9RHOB
          Length = 201

 Score = 91.0 bits (224), Expect = 4e-17,   Method: Composition-based stats.
 Identities = 28/126 (22%), Positives = 55/126 (43%), Gaps = 5/126 (3%)

Query: 137 WASIIRGELSELSQPTDDESLLNMR----VSKLIKKTLSQPEGSRKPVEVERLQKVYVRD 192
           +A+       +  +    ++  N +       +          S +  + +++ + + R+
Sbjct: 31  YAATEAEAGVDAEEKPPKKAPYNAKAGRTEEAIAADLFQDDSSSEEVKKTQKVIETFERN 90

Query: 193 PMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252
                 + +  K  C+  G +  F   +G PYLEVHH++PL  GG+D   N V +  + H
Sbjct: 91  RKAVRDLKRLYK-TCQVTGDDFVFSKVNGEPYLEVHHLVPLGEGGSDDPANLVVISAHIH 149

Query: 253 RELHYS 258
           R LHY+
Sbjct: 150 RMLHYA 155


>UniRef50_D2YH85 Putative uncharacterized protein n=1 Tax=Vibrio mimicus VM603
           RepID=D2YH85_VIBMI
          Length = 208

 Score = 90.6 bits (223), Expect = 5e-17,   Method: Composition-based stats.
 Identities = 28/135 (20%), Positives = 54/135 (40%), Gaps = 5/135 (3%)

Query: 146 SELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQ-KVYVRDPMVKAWILQQSK 204
            +L    D +      +       +S+P       + +      ++RD  +   + +++ 
Sbjct: 62  DDLFYSVDGKGSGRWGLRNFEANQVSEPPVDYDGADKQEYTVSRFIRDSKLSQLVKKKNN 121

Query: 205 GICENCGKNAPFYLNDGNPYLEVHHVIPLSS--GGADTTDNCVALCPNCHRELHYSKNAK 262
             C+ C     F L +G PY E HH+ PL     G D   N + +CPN H  L Y     
Sbjct: 122 YKCQICAF--TFLLPNGKPYAEAHHLKPLGKEHDGPDIEGNLICVCPNHHAMLDYCSLKL 179

Query: 263 ELIEMLYVNINRLQK 277
           ++  ++  + + + K
Sbjct: 180 DVNAIVKNSKHEIMK 194


>UniRef50_B2IKM5 HNH endonuclease n=1 Tax=Beijerinckia indica subsp. indica ATCC
           9039 RepID=B2IKM5_BEII9
          Length = 285

 Score = 90.6 bits (223), Expect = 5e-17,   Method: Composition-based stats.
 Identities = 34/192 (17%), Positives = 64/192 (33%), Gaps = 13/192 (6%)

Query: 90  GNSPRDIRLKMCGYQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSELS 149
           GN  R   +K+ G  ++  +    +         +   +   Y D+ +  I   E   + 
Sbjct: 100 GNVFRKSDMKISGKISFLKKRPDDQD--------LKFPIQEYYDDTNYFGIYETESFNVE 151

Query: 150 QPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICEN 209
           +       +   + +      +        + V        R   +     ++ +  C+ 
Sbjct: 152 KALRFIETVVSSLPEFDSGVSNDIFPENNRILVG-EHLRIERKAALARECKKRDRYRCQI 210

Query: 210 CGKNA-PFYLNDGNPYLEVHHVIPLSS-GG--ADTTDNCVALCPNCHRELHYSKNAKELI 265
           C  +    Y   G  + E HH +PLS   G   +  D+ V +C NCHR LH  +     I
Sbjct: 211 CNFHFVERYGLLGENFAEAHHKVPLSKLDGEVKNCVDDLVTVCANCHRMLHRLEGKPTDI 270

Query: 266 EMLYVNINRLQK 277
             L      + K
Sbjct: 271 VKLRRIFKHVGK 282


>UniRef50_Q1YWU8 Putative uncharacterized protein n=3 Tax=Gammaproteobacteria
           RepID=Q1YWU8_PHOPR
          Length = 244

 Score = 90.3 bits (222), Expect = 7e-17,   Method: Composition-based stats.
 Identities = 28/137 (20%), Positives = 57/137 (41%), Gaps = 6/137 (4%)

Query: 142 RGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQ 201
           R  +S++ +    +  L++ +  +    + +     + +  + +   + R+   +   ++
Sbjct: 106 RTSISKIIERLSKKYRLDVELFSIYPDEIDEKS-FPEGMAKKVVINSFERNKTARNSCIE 164

Query: 202 QSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSSGG----ADTTDNCVALCPNCHRELH 256
           +    C  C  N    Y   G  ++ VHHV+ +SS G     D   + V +CPNCH  LH
Sbjct: 165 EYGLSCSVCEFNFEKAYGELGTGFIHVHHVVDISSIGYAYQVDPKKDLVPVCPNCHAMLH 224

Query: 257 YSKNAKELIEMLYVNIN 273
             K A  + E+      
Sbjct: 225 KRKPAFTVQELKAHLTR 241


>UniRef50_Q6EME6 Hnh endonuclease n=6 Tax=Enterobacteriaceae RepID=Q6EME6_ECOLX
          Length = 302

 Score = 89.9 bits (221), Expect = 8e-17,   Method: Composition-based stats.
 Identities = 35/189 (18%), Positives = 68/189 (35%), Gaps = 10/189 (5%)

Query: 99  KMCGYQAYFSRTGRKEIPSGNRTKRILIN---VPGIYSDSFWASIIRGELSELSQPTDDE 155
           K+     + +    +EI    +     I    V  I    F+++     +   S      
Sbjct: 94  KIASGTKFITVMKSREIKGNPKRNLWTIREELVQAIKELDFFSTNESSSIDFYSDNDLIT 153

Query: 156 SLLNMRVSKLIK-KTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICEN-CGKN 213
           +L       + +    S+    +K     +    Y R   V    L ++   C+  C   
Sbjct: 154 ALEESNHFDVTQTFEYSEKAKPKKAAIEVKNGLSYPRSKSVSKNALNKADYKCQINCDHP 213

Query: 214 APFYLNDGNPYLEVHHVIPLSS-----GGADTTDNCVALCPNCHRELHYSKNAKELIEML 268
                N    Y E HH++P+S         D  +N ++LC NCH+++H  K  ++++  +
Sbjct: 214 TFRRRNSPLNYTEPHHIVPMSKQDYFENSLDVEENIISLCCNCHKQIHLGKGFEDMLRKI 273

Query: 269 YVNINRLQK 277
           Y     + K
Sbjct: 274 YAERKDVLK 282


>UniRef50_C8S4R5 HNH endonuclease n=1 Tax=Rhodobacter sp. SW2 RepID=C8S4R5_9RHOB
          Length = 343

 Score = 89.9 bits (221), Expect = 1e-16,   Method: Composition-based stats.
 Identities = 49/287 (17%), Positives = 100/287 (34%), Gaps = 49/287 (17%)

Query: 3   VFDNNGIELKAECSIGEEDGVYGLILESWGPGDRNKDYNIALDYIIERLVDSGVSQVVVY 62
           VF +N  EL+ E                  P     +  +ALDY ++     G S     
Sbjct: 90  VFADNPAELRKE----------------RNPNWTRDELILALDYYLQH---PGESHDDSS 130

Query: 63  LASSSVRKHMHSLDERKIHPGEYFTLIGNSPRDIRLKMCGYQA---YFSRTGRKEIPSGN 119
              +S+ + +++L +     G   +    +   + +K+  ++A    ++  G+  +  GN
Sbjct: 131 PGVTSLSQQINALAQL---LGHGTSETLRNANGVSMKLLNFRAHDPEYTLRGQVGLQRGN 187

Query: 120 RTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTL----SQPEG 175
           R ++             W      +          +  ++     L +        +   
Sbjct: 188 RLEK-----------ELWDRFAHDQADLKRIADSIKQRIDAPDEDLREALFGPEEPEIAE 236

Query: 176 SRKPVEVERLQKVYVRDPMVKA-----WILQQSKGICENCGKN-APFYLNDGNPYLEVHH 229
           + +   V RL +   R+ ++       +  +Q +  CE C  +    Y   G  ++E HH
Sbjct: 237 AEEGRLVTRLHRFRERNRLLVKRKKESYAKKQGRLCCEACDFDFGAKYGQRGEGFIECHH 296

Query: 230 VIPLSS---GGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNIN 273
             P+SS   G      + V LC NCHR +H       +  +  + + 
Sbjct: 297 TKPVSSLTIGEKTKVSDLVLLCANCHRMVHAKAPWLTVAALKALLVR 343


>UniRef50_A8R8M0 Putative uncharacterized protein n=1 Tax=Eubacterium dolichum DSM
           3991 RepID=A8R8M0_9FIRM
          Length = 508

 Score = 89.9 bits (221), Expect = 1e-16,   Method: Composition-based stats.
 Identities = 53/233 (22%), Positives = 95/233 (40%), Gaps = 14/233 (6%)

Query: 59  VVVYLASSSVRKHMHSLDERKIHPG---EYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEI 115
           +V +  ++ V ++     ER  +     E+  L+    R   +            G+  I
Sbjct: 259 IVGWYKNAKVYRNRKEYLERPFNLETKYEHAILLSEDERTFEIPRAKSNDDNIGFGQANI 318

Query: 116 PSGNRTK-RILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNM----RVSKLIKKTL 170
              N+ + +  ++    Y D++       ++S+ +   DDE    +           +  
Sbjct: 319 WYANKNEHKSFVDEVLKYIDAYTKEKYEKDVSKENLTQDDELNEEITNHRFNGDETFEYT 378

Query: 171 SQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLN-DGNPYLEVHH 229
            +    ++P        +Y R+       +  SK  CE   K+  F    DG PY+E HH
Sbjct: 379 KEVVKKQEPKISFHGVLIYKRERKRANNAIIHSKHQCEIDAKHISFKRKNDGFPYMEAHH 438

Query: 230 VIPLSS-----GGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277
           +IP+S         D  +N V+LC  CHRE+H+ +NA  LI+ LY +  +L K
Sbjct: 439 LIPMSKQDLFEYSLDVEENIVSLCSQCHREIHHGENADALIKKLYNDRKKLLK 491


>UniRef50_Q0KFQ5 Predicted restriction endonuclease n=1 Tax=Ralstonia eutropha H16
           RepID=Q0KFQ5_RALEH
          Length = 371

 Score = 89.9 bits (221), Expect = 1e-16,   Method: Composition-based stats.
 Identities = 35/108 (32%), Positives = 52/108 (48%), Gaps = 9/108 (8%)

Query: 179 PVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLND-GNPYLEVHHVIPLSSG- 236
           P         Y RDP+V A  ++ ++  CE   ++  F  +    PY+E HH+IPLS   
Sbjct: 241 PKRGNGGSWKYPRDPLVAAEAVKSAEYRCELFPEHQTFKSSSKNVPYVEAHHLIPLSRQA 300

Query: 237 ----GADTTDNCVALCPNCHRELHYS---KNAKELIEMLYVNINRLQK 277
                 D T N +ALCP CH+ LH+    +    L  +L    +RLQ+
Sbjct: 301 DFQFSLDITANIIALCPTCHQRLHHGHASERRSPLRRLLSQRKDRLQE 348


>UniRef50_Q64YP3 Putative uncharacterized protein n=1 Tax=Bacteroides fragilis
           RepID=Q64YP3_BACFR
          Length = 216

 Score = 88.7 bits (218), Expect = 2e-16,   Method: Composition-based stats.
 Identities = 35/132 (26%), Positives = 59/132 (44%), Gaps = 10/132 (7%)

Query: 145 LSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSK 204
           LS L +     +L  + + +++       E      ++ R  +  +R+  +   +  +  
Sbjct: 69  LSSLVEYIHFNNLDRLYIEEIVSLKKIPEEAR----QIRREIEAILRNQKLVDELKIRYN 124

Query: 205 GICENCGKNAPFYLNDGNPYLEVHHVIPLSS--GGADTTDNCVALCPNCHRELHYSKNA- 261
            +C+ CG        +   Y EVHH+ PL     G+DT DN V +CPNCH  L Y     
Sbjct: 125 NVCQICGTQIKI--GENKYYSEVHHIWPLGKPHNGSDTLDNMVCVCPNCHTLLDYKAIHL 182

Query: 262 -KELIEMLYVNI 272
            KE+ ++L  NI
Sbjct: 183 NKEIFKVLKHNI 194


>UniRef50_Q3K789 Putative HNH endonuclease n=1 Tax=Pseudomonas fluorescens Pf0-1
           RepID=Q3K789_PSEPF
          Length = 323

 Score = 88.7 bits (218), Expect = 2e-16,   Method: Composition-based stats.
 Identities = 30/97 (30%), Positives = 50/97 (51%), Gaps = 5/97 (5%)

Query: 175 GSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLS 234
           G  +    +       RDP V+  ++ +  G CE  G  A       + +L+VHH++ + 
Sbjct: 221 GRDEASRYQATVSRVARDPSVRKAVIDRCNGRCERPGCGA---SRSYSGFLDVHHILGVE 277

Query: 235 SGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVN 271
              +D   NCVALCPNCHR+ H+S + ++L + L + 
Sbjct: 278 --ISDRVANCVALCPNCHRDAHFSADRQKLNDSLLIV 312


>UniRef50_C3AW04 Putative uncharacterized protein n=1 Tax=Bacillus mycoides Rock1-4
           RepID=C3AW04_BACMY
          Length = 212

 Score = 88.7 bits (218), Expect = 2e-16,   Method: Composition-based stats.
 Identities = 29/112 (25%), Positives = 45/112 (40%), Gaps = 10/112 (8%)

Query: 168 KTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQ----SKGI--CENCGKNA-PFYLND 220
           + +   E   +  ++ R    Y R+  V     +       G   CE CG +    Y   
Sbjct: 98  ELIDLEEEFSEGKQILRTHLSYERNNKVIKSAKEHFKQQHGGKLFCEICGFDFYKTYGEL 157

Query: 221 GNPYLEVHHVIPLS---SGGADTTDNCVALCPNCHRELHYSKNAKELIEMLY 269
           G  Y+E HH IP+S    G     ++ + +C NCHR LH  K    + E+  
Sbjct: 158 GKDYIEGHHTIPVSQLKEGEKTKIEDIIMVCSNCHRMLHRRKPWLSIAELKQ 209


>UniRef50_A6GA77 HNH endonuclease n=1 Tax=Plesiocystis pacifica SIR-1
           RepID=A6GA77_9DELT
          Length = 335

 Score = 88.3 bits (217), Expect = 3e-16,   Method: Composition-based stats.
 Identities = 27/120 (22%), Positives = 47/120 (39%), Gaps = 9/120 (7%)

Query: 167 KKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQS---KGI--CENCGKNA-PFYLND 220
           ++     +   +   + RL + Y R   +     +++    G   CE C  +    Y   
Sbjct: 215 ERVDEDEDEYAEGKVLYRLHRRYERSAKLVRDAKRRALAKHGRLACECCDFDFSEVYGAL 274

Query: 221 GNPYLEVHHVIPLSSGG---ADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277
           G  Y+E HH +P+S          ++   +C NCHR LH SK    +  +    + R  K
Sbjct: 275 GEGYIEAHHRVPVSQMSGKKKAKVEDLAMVCANCHRMLHRSKPLMSVEALRERVLGRRSK 334


>UniRef50_C4F8E8 Putative uncharacterized protein n=1 Tax=Collinsella intestinalis
           DSM 13280 RepID=C4F8E8_9ACTN
          Length = 154

 Score = 88.3 bits (217), Expect = 3e-16,   Method: Composition-based stats.
 Identities = 32/144 (22%), Positives = 57/144 (39%), Gaps = 16/144 (11%)

Query: 112 RKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLS 171
            +E     R  R L  +P     + + +++R            E  L   +  + +    
Sbjct: 6   EQEFTWSPRLTRALERIPEERQAALFRALVRYG------TYGIEPELAWPLDAIFESLRD 59

Query: 172 QPEGSRKPVEVERLQKVYVR---DPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVH 228
             +G +KP+   R      R    P ++  +L++    C+ CG  AP      +  L V 
Sbjct: 60  CIDGKKKPMRARRSSGA-ERKPLPPRIRYEVLERDGYTCQYCGAKAP------SVTLHVD 112

Query: 229 HVIPLSSGGADTTDNCVALCPNCH 252
           H++P++ GG D   N VA C  C+
Sbjct: 113 HIVPVAEGGTDDLSNLVAACEYCN 136


>UniRef50_Q5L3M3 Hnh endonuclease n=1 Tax=Geobacillus kaustophilus
           RepID=Q5L3M3_GEOKA
          Length = 243

 Score = 87.9 bits (216), Expect = 3e-16,   Method: Composition-based stats.
 Identities = 20/94 (21%), Positives = 35/94 (37%), Gaps = 5/94 (5%)

Query: 178 KPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLS-- 234
           +    +     Y R+   +   +      C  CG +    Y   G   + +HH++PLS  
Sbjct: 142 EGTVRQVFVNHYERNRRARRICINHYGSKCVVCGFDFEKTYGPIGKDKIHIHHLVPLSEI 201

Query: 235 --SGGADTTDNCVALCPNCHRELHYSKNAKELIE 266
                 D   +   +CPNCH  +H  +    + E
Sbjct: 202 QKEYEVDPIRDLRPVCPNCHFIIHSKREPFTIEE 235


>UniRef50_C2ECC9 Recombinase n=1 Tax=Lactobacillus ruminis ATCC 25644
           RepID=C2ECC9_9LACO
          Length = 270

 Score = 87.6 bits (215), Expect = 5e-16,   Method: Composition-based stats.
 Identities = 45/244 (18%), Positives = 81/244 (33%), Gaps = 21/244 (8%)

Query: 37  NKDYNIALDYIIERLVDSGV--SQVVVYLASSSVRKHMHSLDERKIHPGEYFTLIGNSPR 94
           +  Y    +  + +    G    Q  +   +  V K        + H  +          
Sbjct: 13  DPRYLYVRNNPLYKDFFEGFFDYQTYLSFKAGKVSKSSGKAQSYRNHLMKIIVFYKEVYG 72

Query: 95  DIRLKMCGYQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSELSQ-PTD 153
                +   +         ++    +  R   N        F+++ I G L  L Q    
Sbjct: 73  SYPTSLESEKTAAGIEAFFKMNDFVKLNREKKN--------FYSATINGYLDYLDQLKIV 124

Query: 154 DESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN 213
           +   +    S+  K  L +    + PV+   LQ  Y R+P        +S   C     +
Sbjct: 125 NAGEIKESPSERYKIKLLKKPVRKSPVQTTILQ--YPRNPHEMLAAKHRSGWKCCYDSSH 182

Query: 214 APFYLN-DGNPYLEVHHVIPLS-----SGGADTTDNCVALCPNCHRELHY--SKNAKELI 265
             F    D   ++E HH+IP+          D  DN + LCP CHR +H+   ++   ++
Sbjct: 183 ETFISENDHKNFVEGHHLIPMQHQCDFEYTIDFADNIIPLCPTCHRRIHFAIKQDRNRML 242

Query: 266 EMLY 269
           E  Y
Sbjct: 243 EKFY 246


>UniRef50_A0YK66 Putative uncharacterized protein n=1 Tax=Lyngbya sp. PCC 8106
           RepID=A0YK66_9CYAN
          Length = 245

 Score = 87.2 bits (214), Expect = 5e-16,   Method: Composition-based stats.
 Identities = 40/194 (20%), Positives = 74/194 (38%), Gaps = 6/194 (3%)

Query: 89  IGNSPRDIRLKMCGYQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSEL 148
           I ++  ++R +     A +       I +  R +  +      Y       I++ + +++
Sbjct: 47  ICDNRNELRWRNNFAWARYGLVCEGYIDNAIRNQWRITEQGEQYLKDLCQEILQVKSTQI 106

Query: 149 SQPTDDESLLNMRVS----KLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSK 204
           +    + +   +  +    +     L +          E   K   R   +   +  + K
Sbjct: 107 TNAAIERAKEIIFPNQKQFEYYLDQLREDGVLSTSETEEIQIKRVKRYQKITDQLKTKYK 166

Query: 205 GICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS--KNAK 262
           G C+       F   +G+ Y E HH++PLS GG+    N V LCPN HR  HY+     K
Sbjct: 167 GCCQIKDCGFTFIQKNGDNYAEAHHLVPLSEGGSQDASNVVILCPNHHRMFHYAVVSIGK 226

Query: 263 ELIEMLYVNINRLQ 276
              E   V IN ++
Sbjct: 227 LAREKRSVIINGVE 240


>UniRef50_C5QAR7 HNH endonuclease n=5 Tax=Firmicutes RepID=C5QAR7_STAEP
          Length = 123

 Score = 87.2 bits (214), Expect = 6e-16,   Method: Composition-based stats.
 Identities = 22/114 (19%), Positives = 45/114 (39%), Gaps = 5/114 (4%)

Query: 165 LIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAP-FYLNDGNP 223
           L      +     +     +    Y R+  ++   ++     C+ CG +    Y + G  
Sbjct: 6   LNLDNELENTEYVEGKPYVQYGIKYERNQALRNEAIKIHGTTCKVCGFDFKAKYGDLGEG 65

Query: 224 YLEVHHVIPL----SSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNIN 273
           ++E+HH+ P+         +   + V LC NCH+ +H +      I+ L   +N
Sbjct: 66  FIEIHHLKPMFSIKREIKVNPQKDLVPLCSNCHKMIHRNTKKPLTIKELTKIVN 119


>UniRef50_A5ELB4 Putative uncharacterized protein n=1 Tax=Bradyrhizobium sp. BTAi1
           RepID=A5ELB4_BRASB
          Length = 283

 Score = 87.2 bits (214), Expect = 6e-16,   Method: Composition-based stats.
 Identities = 39/203 (19%), Positives = 72/203 (35%), Gaps = 12/203 (5%)

Query: 78  RKIHPGEYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEI----PSGNRTKRILINVPGIYS 133
           + I P        ++ R        + AY      + I    P  + TK   +N   +  
Sbjct: 82  KWIKPRTEPGTGSSNKRANDFDQHLWLAYSEALPLRVIFVDGPQSDGTKPSKVNARRL-D 140

Query: 134 DSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDP 193
           D+ WA       +         + L +++S    +        R    + R ++  +R  
Sbjct: 141 DTAWAITEYDLATGRCVMVRGTAPLPVKISAEDLELSGFEGTERSRFVIHRRREGAMRRA 200

Query: 194 MVKAWILQQSKGICEN--CGKNAP-FYLNDGNPYLEVHHVIPLSS----GGADTTDNCVA 246
            +   + +  K +CE   CG +    Y + G  Y +VHH+ PL      G      +   
Sbjct: 201 KISEALSKTGKLVCEVPKCGFDFEARYGSLGKGYAQVHHLTPLHKAPPEGRKIKLSDLAI 260

Query: 247 LCPNCHRELHYSKNAKELIEMLY 269
           +C NCH  +H     +EL  ++ 
Sbjct: 261 VCANCHAMIHAGGECRELARLIR 283


>UniRef50_D1XF45 HNH endonuclease n=3 Tax=Streptomyces RepID=D1XF45_9ACTO
          Length = 354

 Score = 86.8 bits (213), Expect = 8e-16,   Method: Composition-based stats.
 Identities = 33/134 (24%), Positives = 51/134 (38%), Gaps = 13/134 (9%)

Query: 151 PTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAW----ILQQSKGI 206
            T D         +      S PEG      + R  +   R+  ++      +LQ+   +
Sbjct: 202 ATGDLQSFAPAEEEEFGDDFSAPEGR----LLMRRHRARERNKGLRKKKIASVLQRGGQL 257

Query: 207 -CENCGKN-APFYLNDGNPYLEVHHVIPL--SSGGADTTDNCVALCPNCHRELHYSKNAK 262
            CE CG +    Y + G  Y+E HHV+PL  +  G     +   +C NCHR +H      
Sbjct: 258 ACEACGFDFEKIYGDRGAGYIECHHVLPLHVAGEGRTKLGDLALICANCHRMIHRRAPWP 317

Query: 263 ELIEMLYVNINRLQ 276
              E L   I +  
Sbjct: 318 TPGE-LRAAIEQKH 330


>UniRef50_Q0HF94 Putative uncharacterized protein n=1 Tax=Shewanella sp. MR-4
           RepID=Q0HF94_SHESM
          Length = 295

 Score = 86.4 bits (212), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 39/216 (18%), Positives = 85/216 (39%), Gaps = 18/216 (8%)

Query: 71  HMHSLDERKIHPGEY-FTLIGNSPRDIRLKMCGYQAYFSRTGRKEI--PSGNRTKRILIN 127
           +++ L  +   P E        S  ++RL       ++                   + +
Sbjct: 70  YVYDLKTQTYKPEELAIKYPKKSGSELRLYFNRASEFYPDENETWFIFTREGEAIPFIGS 129

Query: 128 VPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQK 187
            P     +F ++ I+ +  E++   DD       V +   + +  PE  +  V  + +  
Sbjct: 130 APANSYLNFTSADIQQKAYEVNASIDD-------VDEEFVRAVLSPEAQKDAVGRQVI-- 180

Query: 188 VYVRDPMVKAWILQQSKGICENCGKNAPFYLND-GNPYLEVHHVIPLSSG-----GADTT 241
           V+ R+    A ++  +   C+    ++ F     G  ++E HH++P++         D  
Sbjct: 181 VHNRNAAKAAKVVCGANYKCQVDVNHSTFISASSGKAFVEAHHLVPVAKSPDFDVSLDVE 240

Query: 242 DNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277
            N V LCPNCHR +HY+++  ++  +      R+ +
Sbjct: 241 PNIVVLCPNCHRAIHYAESQYKIELLTRFYNQRINE 276


>UniRef50_B1I905 HNH endonuclease domain protein n=3 Tax=Streptococcus pneumoniae
           RepID=B1I905_STRPI
          Length = 326

 Score = 86.4 bits (212), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 37/210 (17%), Positives = 82/210 (39%), Gaps = 13/210 (6%)

Query: 47  IIERLVDSGVSQVVVYLASSSVRKHMHSLDERKIHPGEYFTLIGNSPRDIRLKMCGYQAY 106
           ++ R  +  +  +  Y   ++  + +  L+E     GE  + + N+  ++  +    +  
Sbjct: 124 VVRRASEEPIHYLCKYFGITATEESLKQLEE----IGENISRMENTIDNLYQREKQIKTD 179

Query: 107 FSRTGRKEIP-SGNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKL 165
           F+         S +  K + I++P I  D + + I     +  +       L N    + 
Sbjct: 180 FNPPKFILKYFSKDLMKELDIHLPDIKVD-YTSYIFEYVSAGGNSSQKTTILFNGETVEA 238

Query: 166 IKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYL 225
             + +++   S++  + +R          ++  I ++    C+ C   A          L
Sbjct: 239 TAEYIAKKIKSKQTAQAQRSLMT----NKLRTQIKERDHYTCQIC---AASTAEQSLLLL 291

Query: 226 EVHHVIPLSSGGADTTDNCVALCPNCHREL 255
           E+ H++P+S GG  T DN   LC  C+R  
Sbjct: 292 EIDHIVPVSKGGLSTPDNLQTLCWKCNRSK 321


>UniRef50_A3US95 Putative restriction endonuclease n=1 Tax=Vibrio splendidus 12B01
           RepID=A3US95_VIBSP
          Length = 259

 Score = 86.4 bits (212), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 46/227 (20%), Positives = 85/227 (37%), Gaps = 12/227 (5%)

Query: 23  VYGLILESWGPGDRNKDYNIALDYIIERLVDSGVSQVVVYLASSSVRKHMHSLDERKIHP 82
           V+G   +         +  + +   I+ + D      V++         M S  ++ +  
Sbjct: 21  VFGCSPQGGMRRSHKTNTLVIVSNHIKSIYDDRWVGDVLHYTG------MGSKGDQSLTF 74

Query: 83  GEYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEIP-SGNRTKRILINVPGIYSDSFWASII 141
            +  TL  +    + + +         T   E+   G        +  G    ++   + 
Sbjct: 75  QQNKTLAESRTNGVAVHLFEVFKDQEYTYVGEVALDGEPHSETQDDEQGNPRKAYLFPLQ 134

Query: 142 RGELSELSQPTDDESLLNMRVSKLIKKTLSQ-----PEGSRKPVEVERLQKVYVRDPMVK 196
                   +  D +S+ ++RV K  K T+ +      +G +     ++    Y R+  V 
Sbjct: 135 LVTGERQVKKEDRDSVESVRVRKAKKLTVEELQALAAKGRKTATRYQQKSTSYERNIWVA 194

Query: 197 AWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDN 243
               + +KG C+ C K APF    G PYLE HH+  LS GG DT +N
Sbjct: 195 ELAKRLAKGQCQLCLKPAPFKNTKGEPYLETHHIAWLSKGGEDTAEN 241


>UniRef50_Q4K9Y7 Putative uncharacterized protein n=1 Tax=Pseudomonas fluorescens
           Pf-5 RepID=Q4K9Y7_PSEF5
          Length = 282

 Score = 86.0 bits (211), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 39/204 (19%), Positives = 74/204 (36%), Gaps = 29/204 (14%)

Query: 91  NSPRDIRLKMCGYQAY---FSRTGRKEIPSGNRTKRILINVPGIYSDSFWASII---RGE 144
            +   + +K+  ++ +   ++  GR  +  GN+ ++++           W          
Sbjct: 89  RNANGVCMKLNNFRRWDPSYTNNGRTGLAKGNKDEQLV-----------WLEFANDPERL 137

Query: 145 LSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMV----KAWIL 200
              ++    +  ++      L          + +   + R+ +V  RD  +    K   L
Sbjct: 138 AEVVAAINANVQMIPASPIDLSAADDPGFFEAEEGKVLTRVHRVRERDKKIVKRKKEEAL 197

Query: 201 QQSK-GICENCGKNAP-FYLNDGNPYLEVHHVIPLSS---GGADTTDNCVALCPNCHREL 255
            Q     CE CG N    Y  D    ++VHH  PL +   G      +   LC NCHR L
Sbjct: 198 TQHGALQCEACGFNFSQTYGADVEGVIDVHHTKPLHTLQPGDKTKLADLALLCANCHRVL 257

Query: 256 HYSKNA---KELIEMLYVNINRLQ 276
           H  +      E+ E    N+ ++Q
Sbjct: 258 HSQRKWLSVAEVKERYQANLKQIQ 281


>UniRef50_Q5YRW6 Putative endonuclease n=1 Tax=Nocardia farcinica RepID=Q5YRW6_NOCFA
          Length = 123

 Score = 85.3 bits (209), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 8/99 (8%)

Query: 177 RKPVEVERLQKVYVRDPMVKAWILQ-----QSKGICENCGKNAP-FYLNDGNPYLEVHHV 230
           R+   +        R+P ++   L       S+  CE CG +    Y   G  Y+E HH+
Sbjct: 4   REGTLLAANHYRRERNPKLRKAKLAEFRRVHSRVFCEVCGFDFEAVYGERGAGYIECHHI 63

Query: 231 IPLSSGGAD--TTDNCVALCPNCHRELHYSKNAKELIEM 267
           +PL   G       + V LC NCHR +H+        E+
Sbjct: 64  VPLHVSGETVTKLSDLVLLCSNCHRMIHHGSRWLSPEEL 102


>UniRef50_A1F1U9 HNH endonuclease domain protein n=1 Tax=Vibrio cholerae 2740-80
           RepID=A1F1U9_VIBCH
          Length = 210

 Score = 85.3 bits (209), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 4/116 (3%)

Query: 164 KLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNP 223
               K    P G+++P          +RD  +   +       C+ CG      L +G  
Sbjct: 82  AYTPKAADLPTGTKEPEREYTTTYRVLRDTNLARKLKLLYNNSCQICGLQ--IQLPNGKL 139

Query: 224 YLEVHHVIPLS--SGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277
           Y E HH+IPL     G+DT +N + LCPN H    Y      L E+  V+ + + +
Sbjct: 140 YSEAHHIIPLGNPHHGSDTPENIIVLCPNHHVMCDYGAIELSLKEVKQVSSHSISQ 195


>UniRef50_D0S0J8 Hnh endonuclease n=1 Tax=Acinetobacter calcoaceticus RUH2202
           RepID=D0S0J8_ACICA
          Length = 208

 Score = 84.9 bits (208), Expect = 3e-15,   Method: Composition-based stats.
 Identities = 23/94 (24%), Positives = 39/94 (41%), Gaps = 5/94 (5%)

Query: 178 KPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSSG 236
           +    + +   Y R+   +   L+     C  C  +    Y + G   + VHH++ +SS 
Sbjct: 104 EGAAKKIVVNAYERNKEARKKCLEFYGYQCVVCNFDFEKTYGSVGKNCIHVHHLVEISSI 163

Query: 237 GA----DTTDNCVALCPNCHRELHYSKNAKELIE 266
           G     D   +   +CPNCH  +H  K A  + E
Sbjct: 164 GKKYIVDPIKDMAPVCPNCHFIIHQHKPAFSIDE 197


>UniRef50_C3L8D2 Putative uncharacterized protein n=6 Tax=Bacillus anthracis
           RepID=C3L8D2_BACAC
          Length = 211

 Score = 84.9 bits (208), Expect = 3e-15,   Method: Composition-based stats.
 Identities = 31/117 (26%), Positives = 48/117 (41%), Gaps = 11/117 (9%)

Query: 168 KTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQ----SKGI--CENCGKNA-PFYLND 220
           + +   E   +  ++ R    Y R+  V     +       G   CE CG +    Y   
Sbjct: 96  ELIDLEEEFSEGKQILRTHLSYERNNKVIKRAKEHFKQKHGGKIFCEICGFDFHKIYGEL 155

Query: 221 GNPYLEVHHVIPLS---SGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINR 274
           G  ++E HH IP+S    G     ++ + +C NCHR LH +K      E LY  I +
Sbjct: 156 GKDFIEGHHTIPVSQLKEGEKTRIEDIIMVCSNCHRMLHRTKFVLT-KEDLYSIIQK 211


>UniRef50_C2NAK2 HNH endonuclease n=1 Tax=Bacillus cereus ATCC 10876
           RepID=C2NAK2_BACCE
          Length = 381

 Score = 84.5 bits (207), Expect = 4e-15,   Method: Composition-based stats.
 Identities = 34/149 (22%), Positives = 59/149 (39%), Gaps = 12/149 (8%)

Query: 139 SIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEG-SRKPVEVERLQKVYVRDPMVKA 197
           S+++ E+ + +   D    L+     +   T    E    +  E  RL +   R+  +  
Sbjct: 233 SLLQKEMEDFNPIKDVLIRLSEEAITITLDTHVDEEDDFPEGKEKFRLHRYRERNNKLVK 292

Query: 198 WILQQ-----SKGICENCGKNAP-FYLNDGNPYLEVHHVIPLSSGGADT---TDNCVALC 248
              ++      +  CE CG +    Y + G  ++E HH  P+S    D     ++   LC
Sbjct: 293 QAKERFIQVHGRLYCEACGMDFEQVYGDRGRNFIEAHHRKPISEMKNDETTKIEDLAMLC 352

Query: 249 PNCHRELHYSKNAKELIEMLYVNINRLQK 277
           PNCH  +H        +E L V I   +K
Sbjct: 353 PNCHSMIHRK--PLVTVEELRVLIQSKRK 379


>UniRef50_A7C7H9 HNH endonuclease n=2 Tax=Gammaproteobacteria RepID=A7C7H9_9GAMM
          Length = 101

 Score = 84.1 bits (206), Expect = 4e-15,   Method: Composition-based stats.
 Identities = 21/76 (27%), Positives = 36/76 (47%), Gaps = 5/76 (6%)

Query: 197 AWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSS----GGADTTDNCVALCPNC 251
              +++    C  C  +   FY + G  Y+ VHH+IPL+        D   + V LCPNC
Sbjct: 9   QTCIEKYGHKCVVCSFDFEKFYGSIGKKYIHVHHIIPLAEIKKEYQLDPLKDLVPLCPNC 68

Query: 252 HRELHYSKNAKELIEM 267
           H  +H ++    + ++
Sbjct: 69  HAMIHRTQPTLTIQQL 84


>UniRef50_A9VH89 HNH endonuclease n=3 Tax=Bacillus cereus group RepID=A9VH89_BACWK
          Length = 276

 Score = 84.1 bits (206), Expect = 4e-15,   Method: Composition-based stats.
 Identities = 34/176 (19%), Positives = 64/176 (36%), Gaps = 5/176 (2%)

Query: 105 AYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSEL---SQPTDDESLLNMR 161
             + +            KR  IN+        + SI R  L +    ++   +  L   +
Sbjct: 91  YKYIQEANVTKKESGEIKRHHININFSSDLCLYNSIDRFILDDYYFYNEEIVESELDEKK 150

Query: 162 VSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDG 221
              ++++T S  +   + V++    K        K  I       C+ CG    +   + 
Sbjct: 151 RDIILEETKSFIDYKEQYVKIGDKTKRRKESSAQKKRIAILEDHTCQVCGFKEEYIKANN 210

Query: 222 NP--YLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRL 275
                +EV H+I  S GG ++ DN   LCPNCH +        + I+ +     ++
Sbjct: 211 KKGWIIEVDHIIEKSKGGGESFDNLWVLCPNCHAKKTRGVITIDPIKKMVKEKGKV 266


>UniRef50_B0ACA5 Putative uncharacterized protein n=1 Tax=Clostridium bartlettii DSM
           16795 RepID=B0ACA5_9CLOT
          Length = 305

 Score = 84.1 bits (206), Expect = 5e-15,   Method: Composition-based stats.
 Identities = 41/187 (21%), Positives = 77/187 (41%), Gaps = 16/187 (8%)

Query: 107 FSRTGRKEIPSGNRTKRILINV--PGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSK 164
            ++    +    N  +  L +V  P   S+     I   E+  + +   +E+ +   +  
Sbjct: 104 ITKYKENKFTLENLKQNGLKSVQGPSKVSEELANYIKSNEIDMIKETLQEENNIEYDLKN 163

Query: 165 LIKKTLSQP-------EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFY 217
            I K            +  ++   ++   K Y+RD  V    L+++   CE   ++  F 
Sbjct: 164 YIDKINVDENFTYKYDKKKKQKYTIQNGIKTYIRDRKVAMNALKKANHKCEVDSEHEVFL 223

Query: 218 LNDGN-PYLEVHHVIPLS-----SGGADTTDNCVALCPNCHRELHYSKNAKELIEML-YV 270
             +    Y E HH++P++         D  +N V+LC +CH  LHY K  + ++E L Y 
Sbjct: 224 RRNVEVGYTESHHLVPMAYSDIFDVSLDVEENIVSLCSHCHNLLHYGKEFERVLEQLYYE 283

Query: 271 NINRLQK 277
            +N L K
Sbjct: 284 RVNHLNK 290


>UniRef50_Q8YJX6 All8554 protein n=2 Tax=Cyanobacteria RepID=Q8YJX6_ANASP
          Length = 335

 Score = 84.1 bits (206), Expect = 5e-15,   Method: Composition-based stats.
 Identities = 29/122 (23%), Positives = 46/122 (37%), Gaps = 2/122 (1%)

Query: 136 FWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMV 195
               +I    +EL+Q   +  L     ++L  +         +P E+E  Q V VRD   
Sbjct: 154 LTHVLIDSWFNELTQEDIEPLLQVNAFAELQDQLQRTGGKVYQPEELEDEQAVIVRDGAF 213

Query: 196 KAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHREL 255
           +  ++      C  CG       + G   ++  H+ P S    D  DN +ALC N H   
Sbjct: 214 RKIVVSTYNYRCAFCGLQ--ILDSLGQNIVDGSHIKPFSQFYDDRIDNGLALCKNHHWAF 271

Query: 256 HY 257
             
Sbjct: 272 DR 273


>UniRef50_B5ERY9 Restriction endonuclease-like protein n=1 Tax=Acidithiobacillus
           ferrooxidans ATCC 53993 RepID=B5ERY9_ACIF5
          Length = 212

 Score = 83.7 bits (205), Expect = 6e-15,   Method: Composition-based stats.
 Identities = 28/150 (18%), Positives = 58/150 (38%), Gaps = 10/150 (6%)

Query: 130 GIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVY 189
            + +  +     +  L  ++   D + +    ++  +  T    EG+ + V V      Y
Sbjct: 67  SVKTKDYSKLFNKSYLLPVAHSFDPKRV-EFSLADEVVDTSDLHEGAVRLVSVN----AY 121

Query: 190 VRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLS-SGGA---DTTDNC 244
            R+   +   ++     C  CG + A  Y +    ++ V H+ P++  GG    D   + 
Sbjct: 122 ERNAEARRRCVEAHGSSCVVCGFSFAQVYGDVAAGFIHVDHLSPIALKGGNYKVDPVSDL 181

Query: 245 VALCPNCHRELHYSKNAKELIEMLYVNINR 274
           + +CPNCH  +H       + E+      R
Sbjct: 182 LPVCPNCHAVIHLRGGCMSIEELRGHLRAR 211


>UniRef50_Q477P3 HNH endonuclease n=1 Tax=Ralstonia eutropha JMP134
           RepID=Q477P3_RALEJ
          Length = 249

 Score = 83.7 bits (205), Expect = 6e-15,   Method: Composition-based stats.
 Identities = 28/164 (17%), Positives = 54/164 (32%), Gaps = 10/164 (6%)

Query: 112 RKEIPSGNRTKRILINVPGIYSDSFWASII-RGELSELSQPTDDESLLNMRVSKLIKKTL 170
           R+  P   R  +  ++      +  W       +    +       L +   + L +   
Sbjct: 77  RRLDPQYVREGKKGLSQGAKGDEEVWQEFASNPKRCRETAEALLRGLTDDAFADLPEYPD 136

Query: 171 SQPEGSRKPVEVERLQKVYVRDPMV----KAWILQQSKG-ICENCGKN-APFYLNDGNPY 224
                + +   + R      R   +    +  + +Q+    CE C  + A  Y   G  +
Sbjct: 137 EDLTEAPEGRLLTRTHLSRERSRKLVKAKREQVWEQTGKLRCEVCAFDFAKAYGEHGAGF 196

Query: 225 LEVHHVIPLS---SGGADTTDNCVALCPNCHRELHYSKNAKELI 265
           +E HH  PLS           +   +C NCHR LH  +   ++ 
Sbjct: 197 IECHHTKPLSTLPENSKTHIGDLALVCANCHRMLHRGEVWPDVE 240


>UniRef50_C4ZAA3 Putative uncharacterized protein n=1 Tax=Eubacterium rectale ATCC
           33656 RepID=C4ZAA3_EUBR3
          Length = 251

 Score = 83.3 bits (204), Expect = 7e-15,   Method: Composition-based stats.
 Identities = 32/163 (19%), Positives = 60/163 (36%), Gaps = 15/163 (9%)

Query: 118 GNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSR 177
           G R ++    V  +Y    W  +   E++E+ +   D ++   +V  L     +  E   
Sbjct: 70  GQRNRKPTETVKELYGQ--WNVMEFEEITEIVKSVLDGTMEESQVINLEVDEETVSEYDV 127

Query: 178 K---------PVEVERLQKVYVR--DPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLE 226
           +             + ++ V  R         + +     C+ CG+N       G    E
Sbjct: 128 ETYLNFDDNTAALNKTVKSVMERTYSKKKVEMLKRLYAYRCQICGQN--VGEEHGVNIAE 185

Query: 227 VHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLY 269
            HH+   S    +++DN + LCPN H  +H      +  E+ Y
Sbjct: 186 AHHIKYFSKSVDNSSDNLLILCPNHHSLIHVLNPKFDYDELQY 228


>UniRef50_UPI0001BC7063 hypothetical protein VparAQ_18636 n=1 Tax=Vibrio parahaemolyticus
           AQ4037 RepID=UPI0001BC7063
          Length = 300

 Score = 82.6 bits (202), Expect = 1e-14,   Method: Composition-based stats.
 Identities = 31/135 (22%), Positives = 51/135 (37%), Gaps = 10/135 (7%)

Query: 143 GELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQ 202
           G +S L Q       L     +         EG R+     R    + R+  +      +
Sbjct: 166 GYVSHLLQKPYVIDDLGDYEIRENSPEQEYAEGERQV----REASYFKRNSKLVKDAKAE 221

Query: 203 SKGICENCGKNAP--FYLNDGNPYLEVHHVIPLSSGGAD---TTDNCVALCPNCHRELHY 257
              IC+ C  +    +    G  ++E HH  PL     +   T ++   +C NCHR LH 
Sbjct: 222 FGFICQVCDFDFESVYGKELGAGFIECHHKNPLHEKDENYISTLNDVCVVCSNCHRMLHR 281

Query: 258 SKNAKELIEMLYVNI 272
           +K A +  E+L   +
Sbjct: 282 TKPAMKP-EILKAKL 295


>UniRef50_Q984I3 Mll7993 protein n=1 Tax=Mesorhizobium loti RepID=Q984I3_RHILO
          Length = 332

 Score = 82.6 bits (202), Expect = 1e-14,   Method: Composition-based stats.
 Identities = 32/112 (28%), Positives = 46/112 (41%), Gaps = 11/112 (9%)

Query: 171 SQPEGSRKPVEVERLQKVYVRDP----MVKAWILQQSKGI-CENCGKNA-PFYLNDGNPY 224
           +  EGS +   V R  K   RD       KA +L     + CE C       Y + G  +
Sbjct: 218 TDDEGSAEGSVVLRAHKTRERDATLASKKKAAVLAALGELACEVCDMTFQKHYGDHGKGF 277

Query: 225 LEVHHVIPLS---SGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNIN 273
           +EVHH+ P++    G   T      +C NCH+ LH     +  I  L   +N
Sbjct: 278 IEVHHIDPIALSEEGRRTTLAQLACVCSNCHKMLHRGGLRE--ISWLRQQLN 327


>UniRef50_UPI0001B4E4C9 hypothetical protein ShygA5_17857 n=2 Tax=Streptomyces
           RepID=UPI0001B4E4C9
          Length = 303

 Score = 82.6 bits (202), Expect = 1e-14,   Method: Composition-based stats.
 Identities = 27/131 (20%), Positives = 46/131 (35%), Gaps = 5/131 (3%)

Query: 128 VPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQK 187
           VPG+ +       + G L+ +   T     L+  ++  +   L   +G    V  E   +
Sbjct: 107 VPGLRTALSAEPDLLGRLAHVLLDTHFPPSLHTDIAAAVGLDLESADG---AVRTEVTAR 163

Query: 188 VYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVAL 247
              R   ++  +L   +  C  CG +           LE  HV   +  GAD   N + L
Sbjct: 164 DRRRAAELRRQVLVAYEYRCAFCGFDGAIGRV--PVGLEAAHVRWWAFRGADDLANALCL 221

Query: 248 CPNCHRELHYS 258
           C   H+     
Sbjct: 222 CSLHHKLFDRG 232


>UniRef50_C4L074 HNH endonuclease n=1 Tax=Exiguobacterium sp. AT1b
           RepID=C4L074_EXISA
          Length = 272

 Score = 82.6 bits (202), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 35/108 (32%), Positives = 50/108 (46%), Gaps = 4/108 (3%)

Query: 165 LIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPY 224
           ++K+ L +  GS   +   R Q++  R   V   IL ++   CE CG  +PF   DG  Y
Sbjct: 158 IVKQNLQKVSGSSTAI---RKQQIRERSAAVYYSILARANNHCEACGSPSPFETEDG-AY 213

Query: 225 LEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNI 272
           LE+H +   S           A+CPNCH  LH  K+  +  E L   I
Sbjct: 214 LELHSLYSHSDQIILLPGLGAAVCPNCHMRLHKGKDRSQYNEQLQHKI 261


>UniRef50_C5ZWY1 Putative uncharacterized protein n=1 Tax=Helicobacter canadensis
           MIT 98-5491 RepID=C5ZWY1_9HELI
          Length = 410

 Score = 82.6 bits (202), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 36/194 (18%), Positives = 70/194 (36%), Gaps = 15/194 (7%)

Query: 90  GNSPRDIRLKMCGYQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSELS 149
           G + R+ +L++  Y  Y  + G   I      KR    +   Y+ + + S      +   
Sbjct: 189 GENRRNTQLRINLYW-YLEKIGLMNIYKAEIVKRAY-GIDYEYTGNGYYSFECRAPT--F 244

Query: 150 QPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVE---RLQKVYVRDPMVKAWILQQSKGI 206
                +  +N   ++++   L++ +      E+         + R+  +   +  Q+K  
Sbjct: 245 NKNSFQERINFYATRILNNDLTERDIKNLREELNFDENTNNDFKRNINIAQLVRYQTKDE 304

Query: 207 CENCGKNAPFYLNDG-------NPYLEVHHVIPLSSGGA-DTTDNCVALCPNCHRELHYS 258
           C  C                    Y E+HH + +      D  +N   LCP CHR L   
Sbjct: 305 CAACKNKYNIADRSFLLRKFPERYYTEIHHFVSVGKEKELDVVENLTKLCPACHRALGRG 364

Query: 259 KNAKELIEMLYVNI 272
           K +++  + L  NI
Sbjct: 365 KASEQYQKKLIENI 378


>UniRef50_A9B5H7 HNH endonuclease n=1 Tax=Herpetosiphon aurantiacus ATCC 23779
           RepID=A9B5H7_HERA2
          Length = 223

 Score = 82.2 bits (201), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 26/102 (25%), Positives = 38/102 (37%), Gaps = 4/102 (3%)

Query: 168 KTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEV 227
           K  ++P G+R             RD  V +W+       C+ CG            Y E 
Sbjct: 101 KVNNKPAGNRLTRRTINTIDRIQRDTKVSSWVKYIYNYACQICGIRLQI--GQDKFYAEC 158

Query: 228 HHVIPLS--SGGADTTDNCVALCPNCHRELHYSKNAKELIEM 267
           HH+ PL     G D  +N + +CPN H  L Y     +   +
Sbjct: 159 HHIRPLGGVHQGEDIVENVLCVCPNHHALLDYGAIRIDFSTL 200


>UniRef50_B7JSJ9 DNA helicase, putative n=1 Tax=Bacillus cereus AH820
           RepID=B7JSJ9_BACC0
          Length = 278

 Score = 82.2 bits (201), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 31/168 (18%), Positives = 60/168 (35%), Gaps = 5/168 (2%)

Query: 105 AYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSEL---SQPTDDESLLNMR 161
             + +            KR  IN+        + SI    L++     +   ++ L   +
Sbjct: 91  YKYIQEANVTKNKDGGIKRYHINISFSSDLLLYNSIDSFVLNDYYIYDEEIVEDELGEKK 150

Query: 162 VSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDG 221
              ++++  +  +     V+++   K        K  I       C+ CG    +   + 
Sbjct: 151 RDIILEEAKNFIDYKEHYVKIDDKAKRRKESSAQKKRIAILEDHTCQVCGFKEEYIKANN 210

Query: 222 NP--YLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEM 267
                +EV H+I  S GG +T DN   LCPNCH +        + ++ 
Sbjct: 211 KKGWIIEVDHIIEKSKGGGETFDNLWVLCPNCHAKKTRGIIEIDSLKK 258


>UniRef50_B1KV86 Hnh endonuclease n=5 Tax=Firmicutes RepID=B1KV86_CLOBM
          Length = 233

 Score = 81.8 bits (200), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 26/129 (20%), Positives = 44/129 (34%), Gaps = 9/129 (6%)

Query: 156 SLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGI-----CENC 210
            L        +        G  +  +  R      R+  V     +  K       CE C
Sbjct: 105 GLREFEPHDNMVDLTEDDGGFLEGRKKLRQHICIERNAKVIKMAKENFKKKYGVLKCEVC 164

Query: 211 GKN-APFYLNDGNPYLEVHHVIPLSS---GGADTTDNCVALCPNCHRELHYSKNAKELIE 266
           G N    Y   G  ++E HH+ P+S    G     ++ V LC NCH+ +H  +       
Sbjct: 165 GFNFEKKYGKLGEDFIEGHHIKPVSELKEGEKTKVEDIVLLCSNCHKMIHRKRPWLSKKR 224

Query: 267 MLYVNINRL 275
           +  + +  +
Sbjct: 225 LKTLIVQNI 233


>UniRef50_B8FFI4 HNH endonuclease n=1 Tax=Desulfatibacillum alkenivorans AK-01
           RepID=B8FFI4_DESAA
          Length = 299

 Score = 81.4 bits (199), Expect = 3e-14,   Method: Composition-based stats.
 Identities = 35/157 (22%), Positives = 64/157 (40%), Gaps = 14/157 (8%)

Query: 130 GIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVY 189
           GI   + W +      S++   T  + +    + +L    L++      P  +  L++  
Sbjct: 148 GIGQSNIWYA--NKPKSQIHVKTVLKLINEGTIEELPDIDLNKSVKEGNPRLIAHLKR-- 203

Query: 190 VRDPMV----KAWILQQSKG-ICENCGKNAP-FYLNDGNPYLEVHHVIPLSS-GGA--DT 240
            R+  +    K  +L++     CE CG +    Y   G  + EVHH+ PLS   G     
Sbjct: 204 ERNSGIVKTKKEEVLKRKGCLKCEVCGFDFSSVYGEHGYGFCEVHHLQPLSKADGVVQTK 263

Query: 241 TDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277
            ++   +C NCHR +H S     + + L   + +  K
Sbjct: 264 LEDLSIVCSNCHRIIHRSNPMFTIAK-LKRILKQNSK 299


>UniRef50_Q6LSI1 Putative uncharacterized protein MLL7993 n=1 Tax=Photobacterium
           profundum RepID=Q6LSI1_PHOPR
          Length = 207

 Score = 81.4 bits (199), Expect = 3e-14,   Method: Composition-based stats.
 Identities = 36/183 (19%), Positives = 62/183 (33%), Gaps = 15/183 (8%)

Query: 102 GYQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMR 161
           G    +  + RK+    ++ K    N+ G                +            + 
Sbjct: 25  GVDLVWRYSPRKKDGLNDQRKEQFSNMIGGREFVLSLPSKLITFEDTLDDLFRLIACRVI 84

Query: 162 VSKLIKKTLSQ-PEGSRKPVEVERLQKVYVRDPMVKAWILQQS----KGI--CENCGKNA 214
             +L    ++Q  +   +   VER   +  R   +     ++      G   CE CG + 
Sbjct: 85  ADQLDGININQSNDSFPEGKRVERKHYLRERSSALVEKAKKEYALKNNGRLPCEVCGFDF 144

Query: 215 PF-YLNDGNPYLEVHHVIPLS-----SGGADTTDNCVALCPNCHRELHYSKNAK--ELIE 266
              Y   G+ Y+E HH++PLS      G     ++   +C NCHR LH +       L E
Sbjct: 145 RECYGFHGDSYIEAHHIVPLSELCSADGTKTRLEDLAMVCSNCHRMLHRAPRVDLCSLRE 204

Query: 267 MLY 269
              
Sbjct: 205 QFK 207


>UniRef50_B4SDY4 HNH nuclease n=4 Tax=Bacteria RepID=B4SDY4_PELPB
          Length = 309

 Score = 81.0 bits (198), Expect = 4e-14,   Method: Composition-based stats.
 Identities = 19/63 (30%), Positives = 31/63 (49%)

Query: 194 MVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHR 253
            ++  +LQ+    C+ CG +   +      +LE HH+     GG +T +N V LC  CH 
Sbjct: 245 AIRREVLQRDDYRCQQCGWHQEMWNQSDPRHLEAHHIKQHVEGGENTKENLVTLCNICHD 304

Query: 254 ELH 256
           + H
Sbjct: 305 KEH 307


>UniRef50_C4V188 Putative uncharacterized protein n=1 Tax=Selenomonas flueggei ATCC
           43531 RepID=C4V188_9FIRM
          Length = 760

 Score = 81.0 bits (198), Expect = 4e-14,   Method: Composition-based stats.
 Identities = 34/192 (17%), Positives = 71/192 (36%), Gaps = 37/192 (19%)

Query: 93  PRDIRLKMCGYQAYFSRTGRKEIPSGNRTKRILINVPGI------------YSDSFWASI 140
           PRD+R  +   + Y  +    +  + ++  R  ++VP I                +  ++
Sbjct: 569 PRDVRHIL---KYYAQKESEPKFYTFDQVDRSKLDVPAIARHIWDEDLGPKKRKEYLDAL 625

Query: 141 IRGELSELSQPTDDESLLNMRVSKLIKKTLSQPE---------GSRKPVEVERLQKVYVR 191
                  L Q    + +  +R+  +    +S PE           +  +E   L K+   
Sbjct: 626 WESVDDNLLQLFFGKKIYFLRMVDIELAKISDPELYAPEENVTYDKIALENLPLDKIREI 685

Query: 192 DPMV----KAWILQQS----KGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDN 243
           DP +    +     ++      +C +CG+           YL V H++P++ GG    +N
Sbjct: 686 DPALEEELREGAFAKAKTSSGYVCAHCGEVFS-----NRRYLNVDHIVPMNKGGRSVLEN 740

Query: 244 CVALCPNCHREL 255
              LC +C+ + 
Sbjct: 741 LQILCRSCNAKK 752


>UniRef50_UPI0000E87DB3 hypothetical protein MB2181_05395 n=1 Tax=Methylophilales bacterium
           HTCC2181 RepID=UPI0000E87DB3
          Length = 301

 Score = 81.0 bits (198), Expect = 4e-14,   Method: Composition-based stats.
 Identities = 27/143 (18%), Positives = 43/143 (30%), Gaps = 16/143 (11%)

Query: 127 NVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQ----------PEGS 176
           +VP  Y      ++      E  Q         +     IK  + +           EG+
Sbjct: 119 SVPAFYRYDGLFNVEN-YWIEKGQEKFKVYRFRLIEINAIKINIEKNTPKKTSQVTAEGN 177

Query: 177 RKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSS- 235
             P          +RD  +   + +  +  C+ C             Y E  H+ PL   
Sbjct: 178 ESPGRKTVTTSTPIRDQKLAKQVKELYEYKCQICNIQINVPTG---FYAESAHIKPLGKP 234

Query: 236 -GGADTTDNCVALCPNCHRELHY 257
             G D  +N + LCPN H     
Sbjct: 235 HHGPDKVENIICLCPNHHVMFDN 257


>UniRef50_D2AT16 Putative uncharacterized protein n=1 Tax=Streptosporangium roseum
           DSM 43021 RepID=D2AT16_STRRD
          Length = 419

 Score = 81.0 bits (198), Expect = 4e-14,   Method: Composition-based stats.
 Identities = 31/133 (23%), Positives = 46/133 (34%), Gaps = 4/133 (3%)

Query: 148 LSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGIC 207
           L +    +         L ++     +          L     R    K  +L + KG C
Sbjct: 281 LGRENFRQRSDWAEYRYLCEQAEEHEKYGFVQRLRGDLPHRRARSTPAKRAVLLRCKGAC 340

Query: 208 ENCGKNAPFYLND----GNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKE 263
           EN     P   +D    G P L+V H+   + GG D  +  +ALCPNCH      ++   
Sbjct: 341 ENPDCENPGRPSDTSVGGGPILDVDHIDDHAKGGRDYPELMIALCPNCHAVKTRGRSRDV 400

Query: 264 LIEMLYVNINRLQ 276
           L E L        
Sbjct: 401 LRERLREVARERH 413


>UniRef50_Q65MN2 McrA n=2 Tax=Bacillus subtilis group RepID=Q65MN2_BACLD
          Length = 140

 Score = 81.0 bits (198), Expect = 4e-14,   Method: Composition-based stats.
 Identities = 30/118 (25%), Positives = 58/118 (49%), Gaps = 9/118 (7%)

Query: 169 TLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLN-DGNPYLEV 227
            +SQ     +P+  +  Q+ + R+  + +  +  S   CE    +  F       PY+E 
Sbjct: 4   EVSQKRKRPQPIINQGGQRHWTRNASLASKAMMLSNYTCEIDHTHRTFISKSTNMPYVEC 63

Query: 228 HHVIPLSSGG-----ADTTDNCVALCPNCHRELHYSKN--AKELIEMLY-VNINRLQK 277
           HH++P++         D   N V+LCP+CHR +HY ++   +++++ LY    + L+K
Sbjct: 64  HHLVPIAKQEGFKYDLDQLANLVSLCPHCHRLIHYGQDEEKEKMLKKLYDQRKDHLKK 121


>UniRef50_Q2FQI6 HNH endonuclease n=1 Tax=Methanospirillum hungatei JF-1
           RepID=Q2FQI6_METHJ
          Length = 163

 Score = 81.0 bits (198), Expect = 4e-14,   Method: Composition-based stats.
 Identities = 23/99 (23%), Positives = 42/99 (42%), Gaps = 9/99 (9%)

Query: 178 KPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGG 237
           +        +      +++  IL++    C+ CG+            L VHH+IPLS GG
Sbjct: 45  EQEHASIRGRRPQYWNVIRRQILERDGYRCQICGEQRD---------LSVHHIIPLSEGG 95

Query: 238 ADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQ 276
             T  N   LC +CH++ H  +  ++  +  +    R +
Sbjct: 96  DSTASNLRVLCHSCHQQAHGKRAVRDRTKKRFRIRIRYK 134


>UniRef50_D2S2Y4 HNH endonuclease n=1 Tax=Haloterrigena turkmenica DSM 5511
           RepID=D2S2Y4_9EURY
          Length = 221

 Score = 80.6 bits (197), Expect = 5e-14,   Method: Composition-based stats.
 Identities = 17/61 (27%), Positives = 31/61 (50%)

Query: 196 KAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHREL 255
           +  + +     C++CG+ +  +  +    L  HH++PLS GG++   N   LC  CH+  
Sbjct: 30  RKTVYRHDNWTCQSCGRQSGPHAGNEGVRLHAHHIVPLSEGGSNRLSNLETLCEPCHQNQ 89

Query: 256 H 256
           H
Sbjct: 90  H 90


>UniRef50_UPI000197A09F restriction endonuclease n=1 Tax=Helicobacter canadensis MIT
           98-5491 RepID=UPI000197A09F
          Length = 363

 Score = 80.6 bits (197), Expect = 5e-14,   Method: Composition-based stats.
 Identities = 36/194 (18%), Positives = 70/194 (36%), Gaps = 15/194 (7%)

Query: 90  GNSPRDIRLKMCGYQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSELS 149
           G + R+ +L++  Y  Y  + G   I      KR    +   Y+ + + S      +   
Sbjct: 142 GENRRNTQLRINLYW-YLEKIGLMNIYKAEIVKRAY-GIDYEYTGNGYYSFECRAPT--F 197

Query: 150 QPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVE---RLQKVYVRDPMVKAWILQQSKGI 206
                +  +N   ++++   L++ +      E+         + R+  +   +  Q+K  
Sbjct: 198 NKNSFQERINFYATRILNNDLTERDIKNLREELNFDENTNNDFKRNINIAQLVRYQTKDE 257

Query: 207 CENCGKNAPFYLNDG-------NPYLEVHHVIPLSSGGA-DTTDNCVALCPNCHRELHYS 258
           C  C                    Y E+HH + +      D  +N   LCP CHR L   
Sbjct: 258 CAACKNKYNIADRSFLLRKFPERYYTEIHHFVSVGKEKELDVVENLTKLCPACHRALGRG 317

Query: 259 KNAKELIEMLYVNI 272
           K +++  + L  NI
Sbjct: 318 KASEQYQKKLIENI 331


>UniRef50_A5UU02 HNH endonuclease n=16 Tax=Bacteria RepID=A5UU02_ROSS1
          Length = 197

 Score = 80.6 bits (197), Expect = 5e-14,   Method: Composition-based stats.
 Identities = 26/117 (22%), Positives = 44/117 (37%), Gaps = 6/117 (5%)

Query: 152 TDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCG 211
            D   L+     +L  + +S        +         +R P  +  IL + +  C+ CG
Sbjct: 58  QDKAELVEAAQQRLRARGISLEVPLVIRLVRYIRIPRRMRLPCSRRSILLRDRETCQYCG 117

Query: 212 KNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEML 268
                    G  +L V HV+P S GG  T +N V  C +C+         +  + +L
Sbjct: 118 AQP------GRAHLTVDHVVPRSRGGETTWENVVTACRDCNHRKGGRTPEEAGMTLL 168


>UniRef50_Q6NKI3 Putative uncharacterized protein n=1 Tax=Corynebacterium
           diphtheriae RepID=Q6NKI3_CORDI
          Length = 1084

 Score = 80.6 bits (197), Expect = 6e-14,   Method: Composition-based stats.
 Identities = 29/154 (18%), Positives = 57/154 (37%), Gaps = 10/154 (6%)

Query: 110 TGRKEIPSGNRT-KRILINVPGIYSDSF--WASIIRGELSELSQPTDDESLLNMRVSKLI 166
           T R   P GN    R+L  V      +   W +  R  +  + +    E         + 
Sbjct: 457 TPRIGEPVGNPAVDRVLKTVSRWLESATKTWGAPERVIIEHVREGFVTEKRAREMDGDMR 516

Query: 167 KKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLE 226
           ++     +  ++  E   +Q    R  + +   +Q+    C  CG    F  +      E
Sbjct: 517 RRAARNAKLFQEMQEKLNVQGKPSRADLWRYQSVQRQNCQCAYCGSPITFSNS------E 570

Query: 227 VHHVIPLS-SGGADTTDNCVALCPNCHRELHYSK 259
           + H++P +  G  +T +N VA+C  C++    + 
Sbjct: 571 MDHIVPRAGQGSTNTRENLVAVCHRCNQSKGNTP 604


>UniRef50_A4G659 Putative restriction endonuclease n=1 Tax=Herminiimonas
           arsenicoxydans RepID=A4G659_HERAR
          Length = 269

 Score = 80.6 bits (197), Expect = 6e-14,   Method: Composition-based stats.
 Identities = 37/165 (22%), Positives = 62/165 (37%), Gaps = 10/165 (6%)

Query: 99  KMCGYQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWAS----IIRGELSELSQPTDD 154
           K   YQ  F +  +  I   ++   +LIN P      F  +        E S      ++
Sbjct: 83  KKTAYQYSF-KASKGVISYKDKANAVLINQPQYLYPVFLFTECKDGWEFEGSFSVSEIEE 141

Query: 155 ESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNA 214
           + L+  R   +           ++         +  R   V + + + +   C+ C KN 
Sbjct: 142 KYLVLKRGENISNAVDFDESEYQEGERKYVTHLLAERSRSVVSMLKELNDWKCDVCQKN- 200

Query: 215 PFYLNDGNPYLEVHHVIPLSSGGADTT---DNCVALCPNCHRELH 256
            F    G  Y+E HH IP+SS  +       +   LCPNCH+ +H
Sbjct: 201 -FEKEYGVKYIEAHHKIPISSFSSKHPVKSSDFALLCPNCHKAIH 244


>UniRef50_D0WS63 Putative uncharacterized protein n=1 Tax=Vibrio alginolyticus 40B
           RepID=D0WS63_VIBAL
          Length = 203

 Score = 80.6 bits (197), Expect = 6e-14,   Method: Composition-based stats.
 Identities = 28/151 (18%), Positives = 53/151 (35%), Gaps = 14/151 (9%)

Query: 119 NRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRK 178
           N+ K     +   Y+D    ++    +  L     +  L       +        E + +
Sbjct: 59  NQNKESGSYITSNYTD---FTVHSSYVLSLLDSFYNNGLGYEIYQSIDA------ESAIE 109

Query: 179 PVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGA 238
             +++       R+  +      + K  C+ C         +G   ++ HH  PL++ G 
Sbjct: 110 GYKLDSSILRTARNQKLATEAKIRDKHTCQVCRYKMQI---NGKYVIDCHHTNPLATTGK 166

Query: 239 DTTDN--CVALCPNCHRELHYSKNAKELIEM 267
             T+    V LCPNCHR  H       + E+
Sbjct: 167 TNTELSTLVCLCPNCHRIAHLKSPPYTVAEL 197


>UniRef50_B1QVB3 HNH endonuclease domain protein n=2 Tax=Clostridium butyricum
           RepID=B1QVB3_CLOBU
          Length = 492

 Score = 80.2 bits (196), Expect = 6e-14,   Method: Composition-based stats.
 Identities = 30/135 (22%), Positives = 54/135 (40%), Gaps = 15/135 (11%)

Query: 143 GELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQ 202
             L    +   +     +  S  I +  +  EG++K + V      Y R+   +   ++ 
Sbjct: 353 STLLFYIEDKINVYNRQIFPSDEIDEEYTLIEGAKKQIVVN----AYERNVKARNECIEY 408

Query: 203 SKG------ICENCGKN-APFYLNDGNPYLEVHHVIPLSSGG----ADTTDNCVALCPNC 251
            K        CE CG N    Y N     + +HH++ ++  G     +  ++ + +CPNC
Sbjct: 409 YKKINNGQVKCEICGFNFGDIYGNQFRDKINIHHIVEIAQIGQGYIINPKEDLIPVCPNC 468

Query: 252 HRELHYSKNAKELIE 266
           H  LH  K A +  E
Sbjct: 469 HYILHCKKPAYKPEE 483


>UniRef50_Q46AN8 Putative uncharacterized protein n=1 Tax=Methanosarcina barkeri
           str. Fusaro RepID=Q46AN8_METBF
          Length = 268

 Score = 80.2 bits (196), Expect = 6e-14,   Method: Composition-based stats.
 Identities = 34/140 (24%), Positives = 55/140 (39%), Gaps = 9/140 (6%)

Query: 133 SDSFWASIIRGELSELSQPTDDESLLNM----RVSKLIKKTLSQPEGSRKPVEVERLQKV 188
            D     I     + +S  T               +LI+K   +      P   E +  +
Sbjct: 117 EDRILNWISEAVSTYVSSKTAISEEFREGKTLDYDELIQKLDIKY--RNTPEFKETITGL 174

Query: 189 YVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTT--DNCVA 246
             R  ++   I ++    C  CG    F   +G  Y EVHH+I L+    +T    N + 
Sbjct: 175 IQRPSLLSNAIKEKYGYKCMICGYPG-FLKKNGEKYAEVHHMIELNQKAPETLQSWNLLV 233

Query: 247 LCPNCHRELHYSKNAKELIE 266
           +CP CHR+LHY+    E ++
Sbjct: 234 VCPLCHRKLHYADVKSEFLD 253


>UniRef50_C7NQZ2 HNH endonuclease n=1 Tax=Halorhabdus utahensis DSM 12940
           RepID=C7NQZ2_HALUD
          Length = 407

 Score = 80.2 bits (196), Expect = 6e-14,   Method: Composition-based stats.
 Identities = 28/126 (22%), Positives = 45/126 (35%), Gaps = 4/126 (3%)

Query: 140 IIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWI 199
           I    L++  +   D   +    +     +    +    P  VE      VR+  +   +
Sbjct: 240 IFDSILTDEDEQVSDSQAILDAANSSNIDSEEFVDDVITPDSVETTISRTVRNTTLVKEL 299

Query: 200 LQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSS--GGADTTDNCVALCPNCHRELHY 257
                  C+ C  ++P Y      Y E HH+ PL     G DT  N + LCPN H +  Y
Sbjct: 300 KGAYDYECQVC--DSPRYQGPDKRYAEGHHIKPLGEPHNGPDTPSNILVLCPNHHADFDY 357

Query: 258 SKNAKE 263
                +
Sbjct: 358 GLIEID 363


>UniRef50_Q723Z7 Conserved domain protein n=4 Tax=Listeria monocytogenes
           RepID=Q723Z7_LISMF
          Length = 284

 Score = 80.2 bits (196), Expect = 6e-14,   Method: Composition-based stats.
 Identities = 37/166 (22%), Positives = 65/166 (39%), Gaps = 22/166 (13%)

Query: 133 SDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQP---------------EGSR 177
           S+ F+++ +   L+ ++    D   +              P                 SR
Sbjct: 99  SNRFYSATLSCYLAYVTFKNSDAEEIMDNQIISTLNNFENPAQVVKENKSTYLVRVPKSR 158

Query: 178 KPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYL-NDGNPYLEVHHVIPLS-- 234
                      Y R+ +      ++   +CE   ++  F    DG PY+E HH+IP++  
Sbjct: 159 ASKRKNNNVYSYPRNYVEAIEARRRCGWVCEFNQEHKTFINIKDGKPYVEGHHLIPMAVQ 218

Query: 235 ---SGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277
                  D  DN + LCP CHR++HY+  +++  EML    N  +K
Sbjct: 219 DYYDNTIDFADNIICLCPTCHRKIHYAVQSEK-KEMLIKIFNEREK 263


>UniRef50_C7V3C1 Predicted protein n=1 Tax=Enterococcus faecalis T11
           RepID=C7V3C1_ENTFA
          Length = 288

 Score = 79.9 bits (195), Expect = 8e-14,   Method: Composition-based stats.
 Identities = 31/132 (23%), Positives = 50/132 (37%), Gaps = 7/132 (5%)

Query: 149 SQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICE 208
           S+      + ++  ++ I+   S    S +       ++   +   +K   L      CE
Sbjct: 136 SEILPFIEIDDISETRNIELDYSNTAFSTEDTITLPEKERIKKSARLKKECLASHNYQCE 195

Query: 209 NCGKNAPFYL-NDGNPYLEVHHVIPLS-----SGGADTTDNCVALCPNCHRELHYSKNAK 262
               +  F        Y+E HH+IPLS         D T N   LCP CHR +HY K   
Sbjct: 196 INPLHETFISSKTNRNYMETHHIIPLSAQRYYKNKLDCTANLSCLCPTCHRSIHYGKKED 255

Query: 263 ELIEMLYVNINR 274
           +L  +L     +
Sbjct: 256 KLP-LLKQIYEK 266


>UniRef50_D2QLF7 HNH endonuclease n=1 Tax=Spirosoma linguale DSM 74
           RepID=D2QLF7_9SPHI
          Length = 267

 Score = 79.9 bits (195), Expect = 9e-14,   Method: Composition-based stats.
 Identities = 21/83 (25%), Positives = 36/83 (43%), Gaps = 5/83 (6%)

Query: 187 KVYVRDPMVKAWILQQSKGICENCGKNAPF-YLNDGNPYLEVHHVIPLS----SGGADTT 241
             Y +D   K   L+    +C  C  +  + Y + G  +++VHH++P S        D  
Sbjct: 170 NSYEKDLEAKQLCLEHFGPVCIICNIDFEYAYGSIGKNFIQVHHIVPASSIPKRYIVDPI 229

Query: 242 DNCVALCPNCHRELHYSKNAKEL 264
            +   +CPNCH  LH  +    +
Sbjct: 230 RDLRPVCPNCHAMLHTQEPPYTI 252


>UniRef50_Q3A7T9 Predicted restriction endonuclease n=6 Tax=Deltaproteobacteria
           RepID=Q3A7T9_PELCD
          Length = 374

 Score = 79.9 bits (195), Expect = 9e-14,   Method: Composition-based stats.
 Identities = 24/119 (20%), Positives = 40/119 (33%), Gaps = 4/119 (3%)

Query: 140 IIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWI 199
           I      ++     ++  +N        +   +  G     + E   K  VRD   +  I
Sbjct: 200 ITAHFSEDVHPALIEQGAVNAEAFDYSLRLYEKAHGKI--GDKEEKYKPAVRDQGFRRAI 257

Query: 200 LQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258
           +      C  CG        DG+  ++  H++P S    D   N +ALC  CH      
Sbjct: 258 VNAYGHRCALCGIRM--LTPDGHTVVDAAHIVPWSESHNDDISNGMALCRLCHWTFDEG 314


>UniRef50_D0LYP9 HNH endonuclease n=1 Tax=Haliangium ochraceum DSM 14365
           RepID=D0LYP9_HALO1
          Length = 174

 Score = 79.9 bits (195), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 23/119 (19%), Positives = 42/119 (35%), Gaps = 6/119 (5%)

Query: 152 TDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCG 211
             D+  +     K+++                 +++  VR    +  +  +    C+ CG
Sbjct: 26  YLDKVEVVRSYDKVLRSASRVLPTPAVVRLFRFVRRHQVRIAFSRRNVFLRDGYRCQYCG 85

Query: 212 KNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYV 270
           +  P         L   HV+P S GG  + DN V  C  C+R       A+  +E+   
Sbjct: 86  EVLP------AAELTTDHVVPRSRGGPTSWDNVVTACSPCNRRKGGRSPAQAHMELAKR 138


>UniRef50_B0TQV8 Restriction endonuclease-like protein n=1 Tax=Shewanella
           halifaxensis HAW-EB4 RepID=B0TQV8_SHEHH
          Length = 289

 Score = 79.5 bits (194), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 38/154 (24%), Positives = 58/154 (37%), Gaps = 11/154 (7%)

Query: 130 GIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVY 189
             Y  SF  + +R         T+   + N+   K +        G  +   + R+ K  
Sbjct: 125 EFYHSSFVEA-VRYSACTQGSITEVNDIKNLTQLKGVSSENVGDYGVDEGKPIYRVHKTR 183

Query: 190 VRDPMV----KAWILQQSKG-ICENCGKNA-PFYLNDGNPYLEVHHVIPLS---SGGADT 240
            RDP +    K  +L  +    CE C  +    Y + G  + E HH+ PL+   S     
Sbjct: 184 ERDPKLTKDKKQQVLSITGKLCCEICNFDFYECYGDLGLGFAECHHLEPLALRESNKKTK 243

Query: 241 TDNCVALCPNCHRELHYSKNAKELIEMLYVNINR 274
            D+   LC NCHR +HY      + E L     R
Sbjct: 244 LDDLAILCANCHRMIHYPTQWLSV-EELKEKYER 276


>UniRef50_C3GU40 HNH endonuclease n=2 Tax=Bacillus thuringiensis RepID=C3GU40_BACTU
          Length = 622

 Score = 79.5 bits (194), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 29/129 (22%), Positives = 54/129 (41%), Gaps = 9/129 (6%)

Query: 133 SDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKP-----VEVERLQK 187
           +      ++ GE     Q ++DE L  + + + + K ++  +          V  + ++ 
Sbjct: 407 TSDMAKDVVEGEEKPEVQLSNDEVLAILEMGEALDKEINPDDFGSMGDMFGEVTHQDVKN 466

Query: 188 VYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVAL 247
               DP++K   L +    C  CG             +  HH++P+ +GG DT  N + L
Sbjct: 467 RKPVDPIIKQQTLARDDYRCRCCG----TGGKAFLSTIIFHHIVPVHAGGPDTVANGLTL 522

Query: 248 CPNCHRELH 256
           C +CH  LH
Sbjct: 523 CDSCHITLH 531


>UniRef50_B9LX84 HNH endonuclease n=1 Tax=Halorubrum lacusprofundi ATCC 49239
           RepID=B9LX84_HALLT
          Length = 299

 Score = 79.5 bits (194), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 17/61 (27%), Positives = 28/61 (45%), Gaps = 3/61 (4%)

Query: 196 KAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHREL 255
           +  + ++    C+ CG       + GN  L  HH  P S GG+    N   +C +CH ++
Sbjct: 13  RKKVYKRDNYRCQKCGSRG---GSRGNTELHAHHKKPKSKGGSHRFSNLTTVCKSCHEDI 69

Query: 256 H 256
           H
Sbjct: 70  H 70


>UniRef50_UPI0001BCB4D2 hypothetical protein VparK_03069 n=1 Tax=Vibrio parahaemolyticus
           K5030 RepID=UPI0001BCB4D2
          Length = 289

 Score = 79.1 bits (193), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 21/129 (16%), Positives = 42/129 (32%), Gaps = 4/129 (3%)

Query: 137 WASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQP--EGSRKPVEVERLQKVYVRDPM 194
           +  +   +         +  L++   SK+I+    +   E        E       RDP 
Sbjct: 108 YNVMAGFDEESFRTILANPKLIDDIASKIIQDNFPETLQEELFVRFGFEVNTSTKSRDPE 167

Query: 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254
            +  +L+     C  CG +    +++    +E  H+      G     N +ALC   H+ 
Sbjct: 168 FRRKVLRAYNYKCAVCGFD--LAMDNVTVGVEAAHIKWKQYFGPCDISNGIALCSIHHKA 225

Query: 255 LHYSKNAKE 263
                   +
Sbjct: 226 FDRGAITLD 234


>UniRef50_C3IFK4 5-methylcytosine-specific restriction enzyme A n=1 Tax=Bacillus
           thuringiensis IBL 4222 RepID=C3IFK4_BACTU
          Length = 328

 Score = 79.1 bits (193), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 41/178 (23%), Positives = 66/178 (37%), Gaps = 18/178 (10%)

Query: 108 SRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIK 167
             TG K +   N     L N+     D     +   E +   Q      +    V  +I 
Sbjct: 144 ESTGEKVLNVTNPRSIFLTNISESLRDLIIEILRNPEANYQYQ------VEQENVGSVII 197

Query: 168 KTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLN-DGNPYLE 226
           + + +   S+   E       Y RD       +  +   CE    +  F        Y+E
Sbjct: 198 EDIPKNVPSKSKGE---GSGAYKRDFKTAKNAIVLANYKCEIDLNHEYFISKVTKRNYVE 254

Query: 227 VHHVIPLS-----SGGADTTDNCVALCPNCHRELHYSKNA--KELIEMLY-VNINRLQ 276
            HH+IP+          D   N ++LC  CH++LH+++    + LI+ LY   INRL 
Sbjct: 255 AHHLIPMGFQDDFQKSIDVEANIISLCAYCHKKLHHAEYKVIEPLIKKLYDARINRLN 312


>UniRef50_Q3EYN0 HNH endonuclease family protein n=1 Tax=Bacillus thuringiensis
           serovar israelensis ATCC 35646 RepID=Q3EYN0_BACTI
          Length = 422

 Score = 79.1 bits (193), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 29/129 (22%), Positives = 54/129 (41%), Gaps = 9/129 (6%)

Query: 133 SDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKP-----VEVERLQK 187
           +      ++ GE     Q ++DE L  + + + + K ++  +          V  + ++ 
Sbjct: 207 TSDMAKDVVEGEEKPEVQLSNDEVLAILEMGEALDKEINPDDFGSMGDMFGEVTHQDVKN 266

Query: 188 VYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVAL 247
               DP++K   L +    C  CG             +  HH++P+ +GG DT  N + L
Sbjct: 267 RKPVDPIIKQQTLARDDYRCRCCGT----GGKAFLSTIIFHHIVPVHAGGPDTVANGLTL 322

Query: 248 CPNCHRELH 256
           C +CH  LH
Sbjct: 323 CDSCHITLH 331


>UniRef50_B8F0E2 Restriction endonuclease-like protein n=1 Tax=Thauera sp. MZ1T
           RepID=B8F0E2_THASP
          Length = 333

 Score = 78.7 bits (192), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 23/108 (21%), Positives = 35/108 (32%), Gaps = 2/108 (1%)

Query: 151 PTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENC 210
           P  D+ L +    +L ++         +        K   R    +  ++      C  C
Sbjct: 169 PLADDDLTDAFKEELEREGKPFKLIDDEAGTTTVTVKKVARALAFRTIVIALYDERCAVC 228

Query: 211 GKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258
           G         G   +E  HV+P S  GAD   N V+LC   H      
Sbjct: 229 G--EGLKSPAGATEVEAAHVVPRSQFGADDARNGVSLCKAHHWAFDRG 274


>UniRef50_A3WFM1 5-methylcytosine-specific restriction enzyme A n=1
           Tax=Erythrobacter sp. NAP1 RepID=A3WFM1_9SPHN
          Length = 288

 Score = 78.7 bits (192), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 54/232 (23%), Positives = 81/232 (34%), Gaps = 32/232 (13%)

Query: 74  SLDERKIHPGEYF---TLIGNSPRDIRLKMCGY----QAYFSRTGRKEIPSGNRTKRILI 126
           S DE+ I   E+F    L      D  L M G     +     TGR   P     K    
Sbjct: 38  SSDEKTIVV-EHFGADDLAKYVGNDTVLAMAGLDARREFRLFPTGRIVQPKLKYPKPNNS 96

Query: 127 NVPGIYSDS--------FWASIIRGELSELSQPTDD----------ESLLNMRVSKLIKK 168
            +   ++D         FW    RG+   L Q TD            S     + +    
Sbjct: 97  ELRLYFNDEEFKVKEGHFWGVFERGDDIWLFQATDVFMDRIRKHGLASEDGGSILEPEVD 156

Query: 169 TLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICE-NCGKNAPFYLNDGNPYLEV 227
                   + P ++   QK + RDP V A  L+ +   CE           + G P++E 
Sbjct: 157 DYQSEINQKAPSQITSTQKAWSRDPKVAAEALKNASFECELYPELPTFTSRSTGYPFMEA 216

Query: 228 HHVIPLS-----SGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINR 274
           HH+IP+          D  DN   L P  HR+LH ++    + ++  +   R
Sbjct: 217 HHLIPMKAQADFDVSLDVVDNICCLSPFAHRKLHMAEFDDIIDDLERLIAKR 268


>UniRef50_Q6NMJ9 At2g23840 n=6 Tax=Magnoliophyta RepID=Q6NMJ9_ARATH
          Length = 284

 Score = 78.7 bits (192), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 23/98 (23%), Positives = 42/98 (42%), Gaps = 9/98 (9%)

Query: 173 PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIP 232
           P   R P  ++ +++  V++ + +  IL +    C+ C              L + HV+P
Sbjct: 153 PAVLRVPHLLQVVKRRRVKNSLSRKNILLRDDYTCQYCSSREN---------LTIDHVMP 203

Query: 233 LSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYV 270
           +S GG  T  N VA C  C+         +  +++L V
Sbjct: 204 VSRGGEWTWQNLVAACSRCNSRKGQKTADEAHMKLLKV 241


>UniRef50_B7A588 HNH endonuclease n=1 Tax=Thermus aquaticus Y51MC23
           RepID=B7A588_THEAQ
          Length = 178

 Score = 78.7 bits (192), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 20/79 (25%), Positives = 36/79 (45%), Gaps = 8/79 (10%)

Query: 185 LQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNC 244
           +++   R P+ +  +L++ +  C+ CG+            L V HV+P S GG  T +N 
Sbjct: 72  VRRGPARVPLNRRNVLRRDRYTCQYCGRQG--------GELTVDHVLPKSRGGRSTWENL 123

Query: 245 VALCPNCHRELHYSKNAKE 263
           VA C  C+ +       + 
Sbjct: 124 VAACRACNLKKGDRTPEEA 142


>UniRef50_Q82RB7 Putative reverse transcriptase homolog; similar to GII intron n=1
           Tax=Streptomyces avermitilis RepID=Q82RB7_STRAW
          Length = 588

 Score = 78.7 bits (192), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 32/168 (19%), Positives = 60/168 (35%), Gaps = 21/168 (12%)

Query: 130 GIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVY 189
           G     +W +   G  S+    T +  L       + + TL + + S    E+E      
Sbjct: 420 GWIKRRYWGTFQPGRSSKWVFGTPEHYLPQASWMPIQRHTLVKDDASPDDQELEEYWGNR 479

Query: 190 VR-------DPMVKAWILQQSKGICENCGKNAP----FYLNDGNPY----------LEVH 228
            R       +P     +  + +G+C  CG +      F  +D   +          + VH
Sbjct: 480 RRKRIQAVGEPKKILSLAYRQRGLCPRCGLDLIDGVGFDPDDVQDWANWFTGSLRAIHVH 539

Query: 229 HVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQ 276
           H+   S GG+D   N   +   CHR+ H      +       +++R++
Sbjct: 540 HLTYRSKGGSDHPSNLELIHTTCHRQAHAGDRKYDAHRRPQASLSRMR 587


>UniRef50_Q2S547 Putative uncharacterized protein n=1 Tax=Salinibacter ruber DSM
           13855 RepID=Q2S547_SALRD
          Length = 299

 Score = 78.7 bits (192), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 29/136 (21%), Positives = 54/136 (39%), Gaps = 6/136 (4%)

Query: 143 GELSELSQPTDDESLLNMRVSKLIKKTL---SQPEGSRKPVEVERLQKVYVR-DPMVKAW 198
           G   ++ Q   ++S L   +++L+  +    S  E     V ++       R DP  +  
Sbjct: 117 GFSDDIHQAFRNDSELRRGIARLLLSSHFPTSLHEDIATAVSLDLEGAASERRDPEFRTQ 176

Query: 199 ILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258
           +LQ  +  C  CG N    ++     +E  H+    + G D   N +ALC   H+ L   
Sbjct: 177 VLQAYQYRCAICGFNLQLGMSGTPIGVEAAHIKWKQARGPDEISNGIALCALHHKMLDKG 236

Query: 259 KNAKELIEMLYVNINR 274
                + E L + ++ 
Sbjct: 237 ALH--VTEDLRLFVSE 250


>UniRef50_C1YI89 Predicted restriction endonuclease n=2 Tax=Actinomycetales
           RepID=C1YI89_NOCDA
          Length = 290

 Score = 78.3 bits (191), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 19/69 (27%), Positives = 25/69 (36%), Gaps = 2/69 (2%)

Query: 190 VRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCP 249
           VRDP  +  +L   +  C  CG             LE  H+   S  G +  DN + LCP
Sbjct: 162 VRDPRFRETVLTAYEHRCAFCGYEGRLDGVSVG--LEAAHIRWWSYDGPNDLDNGLCLCP 219

Query: 250 NCHRELHYS 258
             H      
Sbjct: 220 THHLLFDRG 228


>UniRef50_Q2FRM5 HNH endonuclease n=1 Tax=Methanospirillum hungatei JF-1
           RepID=Q2FRM5_METHJ
          Length = 334

 Score = 78.3 bits (191), Expect = 3e-13,   Method: Composition-based stats.
 Identities = 21/94 (22%), Positives = 36/94 (38%), Gaps = 11/94 (11%)

Query: 166 IKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYL 225
           I   + + E    P++         R+  +   +       C+ C         +    +
Sbjct: 221 IHSLIQEEERRILPMQT-------KRNRYLAYLVKNLHGNCCQIC----SAMGEETTGPV 269

Query: 226 EVHHVIPLSSGGADTTDNCVALCPNCHRELHYSK 259
           EVHH+IPLS  G D  +N + LC   H+ +H   
Sbjct: 270 EVHHIIPLSRQGKDLAENMLTLCAPHHQAVHAGS 303


>UniRef50_C1V6S3 HNH endonuclease n=1 Tax=Halogeometricum borinquense DSM 11551
           RepID=C1V6S3_9EURY
          Length = 357

 Score = 78.3 bits (191), Expect = 3e-13,   Method: Composition-based stats.
 Identities = 21/73 (28%), Positives = 32/73 (43%), Gaps = 3/73 (4%)

Query: 192 DPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSG-GADTTDNCVALCPN 250
           DP  +  +L++ K  C+ CG+  P     G   L VHH+     G G    +N   LC +
Sbjct: 36  DPDTRDDVLEKYKHRCQACGRRGP--GKGGLATLHVHHIERDPDGMGEHDLENLTLLCRS 93

Query: 251 CHRELHYSKNAKE 263
           CH   H     ++
Sbjct: 94  CHSWFHQQSTPED 106


>UniRef50_B7UQU7 Predicted restriction endonuclease n=81 Tax=Gammaproteobacteria
           RepID=B7UQU7_ECO27
          Length = 301

 Score = 77.9 bits (190), Expect = 3e-13,   Method: Composition-based stats.
 Identities = 23/113 (20%), Positives = 40/113 (35%), Gaps = 8/113 (7%)

Query: 151 PTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENC 210
            T  + +L    ++ I++ ++   G               RDP+ +  +L+     C  C
Sbjct: 143 NTLAQQILEAHFTESIQEEIADELGFDLQQI------RKQRDPLFRKNVLRAYNYQCAIC 196

Query: 211 GKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKE 263
           G N     +D    LE  H+     GG     N +ALC   H+         +
Sbjct: 197 GFNMRH--DDTTVALEAAHIKWKQHGGPCEIPNGLALCAIHHKAFDKGSIGLD 247


>UniRef50_C6WXV3 HNH endonuclease n=3 Tax=Proteobacteria RepID=C6WXV3_METML
          Length = 238

 Score = 77.9 bits (190), Expect = 4e-13,   Method: Composition-based stats.
 Identities = 36/187 (19%), Positives = 63/187 (33%), Gaps = 28/187 (14%)

Query: 91  NSPRDIRLKMCGYQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSELSQ 150
            +P  +  K+   +   +  G   +   +R   +   V    + S    I          
Sbjct: 62  RNPVGVAFKLQNLRQVATGKGLGNVSETDRAVWLEFGVSAAATKSLANLI---------- 111

Query: 151 PTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWIL--QQ--SKGI 206
                 +     S+ +++ +   EG      +  L     R+P ++  +L  ++      
Sbjct: 112 ---RAGVTAFEASEPVQEDVVFAEGRV----ITELHTRREREPKLRGQLLSSRRVSGNLF 164

Query: 207 CENCGKNAPFYLN-DGNPYLEVHHVIPLSSGG--ADTTDNCVALCPNCHRELHY----SK 259
           CE CG             + E HH+IPLS+ G       +   LC NCHR LH      K
Sbjct: 165 CEMCGAPPHTSNAMLQEAHFEAHHIIPLSNTGVRKTRLSDLALLCANCHRLLHRAIAIKK 224

Query: 260 NAKELIE 266
               + E
Sbjct: 225 RWLTVAE 231


>UniRef50_B4D4V1 HNH endonuclease n=1 Tax=Chthoniobacter flavus Ellin428
           RepID=B4D4V1_9BACT
          Length = 212

 Score = 77.5 bits (189), Expect = 4e-13,   Method: Composition-based stats.
 Identities = 29/113 (25%), Positives = 46/113 (40%), Gaps = 6/113 (5%)

Query: 166 IKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYL 225
             +  +      +P  V +     +RD  + + +      IC+ CG            Y 
Sbjct: 83  DARAANDISQPSQPDRVLQRISRIIRDTAISSELKLLYDHICQLCGTQLVVCDRL---YS 139

Query: 226 EVHHVIPLSS--GGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQ 276
           E HH+ PL     G+DT DN + +CPNCH  L Y+    +  E L    +R+ 
Sbjct: 140 EAHHIRPLGRPHDGSDTRDNLLCVCPNCHVLLDYAAIPIQP-EALKHLKHRIS 191


>UniRef50_A3HSL8 Putative uncharacterized protein n=1 Tax=Algoriphagus sp. PR1
           RepID=A3HSL8_9SPHI
          Length = 316

 Score = 77.2 bits (188), Expect = 5e-13,   Method: Composition-based stats.
 Identities = 25/126 (19%), Positives = 48/126 (38%), Gaps = 2/126 (1%)

Query: 133 SDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRD 192
            DS    +++      S+     +    +  K +++ +         ++V   + VYVR+
Sbjct: 134 RDSMRNMLVKFYFPSSSEHYFRANREQGKYLKEVQQYVLNEVPKVMRLQVAEEEVVYVRN 193

Query: 193 PMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252
              K  + +  +  C   G        +G   ++  H++P S    D   N +ALCPN H
Sbjct: 194 WTFKKLVPKVYQSTCAISGM--KVGSINGRSLIDACHIVPFSQDQDDRISNGIALCPNLH 251

Query: 253 RELHYS 258
           R     
Sbjct: 252 RAFDSG 257


>UniRef50_B0N4T9 Putative uncharacterized protein n=1 Tax=Clostridium ramosum DSM
           1402 RepID=B0N4T9_9FIRM
          Length = 329

 Score = 77.2 bits (188), Expect = 5e-13,   Method: Composition-based stats.
 Identities = 39/138 (28%), Positives = 62/138 (44%), Gaps = 6/138 (4%)

Query: 146 SELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKG 205
           ++         + ++ ++     + S     +  +   +  KVY R+  V    L  +  
Sbjct: 175 NDQLDDMLKTVITDIIINPSKIYSYSDVLKPKPKLVENKFNKVYKRNKAVAINALGIANF 234

Query: 206 ICENCGKNAPFYLN-DGNPYLEVHHVIPLS-----SGGADTTDNCVALCPNCHRELHYSK 259
            CE   K+  F    DG PY E HH+IP++         D  +N V+LC NCH E+HY +
Sbjct: 235 SCEIDKKHKTFKRKKDGVPYTEPHHLIPMAFQDEFDFSIDIEENIVSLCSNCHNEIHYGE 294

Query: 260 NAKELIEMLYVNINRLQK 277
           NA+ELI  LY     L +
Sbjct: 295 NARELITKLYYERKSLLE 312


>UniRef50_D2RPV1 Restriction endonuclease-like protein n=1 Tax=Haloterrigena
           turkmenica DSM 5511 RepID=D2RPV1_9EURY
          Length = 496

 Score = 77.2 bits (188), Expect = 6e-13,   Method: Composition-based stats.
 Identities = 24/124 (19%), Positives = 36/124 (29%), Gaps = 6/124 (4%)

Query: 139 SIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERL----QKVYVRDPM 194
            I      E    +  +       +    +T    +GS  P+  +       +  VR   
Sbjct: 316 EIEDPTEFEALADSVVDGDTETGSASAESETSDDSDGSEPPLTADEEEFTATQRRVRSST 375

Query: 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254
               +       C  CG  A      G   +E  H+ P    G DT  N +ALC   H  
Sbjct: 376 FAKRVKTAYGRRCAICG--ASRESPAGTVDIEAAHIYPKKENGRDTVRNGLALCRLHHWA 433

Query: 255 LHYS 258
               
Sbjct: 434 FDAG 437


>UniRef50_C4XM37 Putative uncharacterized protein n=1 Tax=Desulfovibrio magneticus
           RS-1 RepID=C4XM37_DESMR
          Length = 251

 Score = 76.8 bits (187), Expect = 7e-13,   Method: Composition-based stats.
 Identities = 24/101 (23%), Positives = 44/101 (43%), Gaps = 9/101 (8%)

Query: 176 SRKPVEVERLQKVYVRDPMV----KAWILQQSK-GICENCGKNA-PFYLNDGNPYLEVHH 229
           +R+   + ++     R   +    K +++       CE CG +   FY   G  + EVHH
Sbjct: 144 AREGKVLTKIHVQRERSKSLIESKKKYVMNTCGVLECEVCGFSFHKFYGERGKNFAEVHH 203

Query: 230 VIPLS---SGGADTTDNCVALCPNCHRELHYSKNAKELIEM 267
           + PLS   +  +   ++   +C NCHR +H       + E+
Sbjct: 204 IKPLSYLDAEASTKIEDLAIVCSNCHRMIHSQLPWLAIQEL 244


>UniRef50_A9AVZ1 HNH nuclease n=1 Tax=Herpetosiphon aurantiacus ATCC 23779
           RepID=A9AVZ1_HERA2
          Length = 323

 Score = 76.8 bits (187), Expect = 7e-13,   Method: Composition-based stats.
 Identities = 26/131 (19%), Positives = 47/131 (35%), Gaps = 13/131 (9%)

Query: 128 VPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQK 187
           +   ++   W ++  G +++++    D S L +  S   ++   +   +  P +VE    
Sbjct: 146 IQQYFTPELWTAL--GMIAQINTEIFDYSKLLIEQS---QRMFREIPATDAPYQVEV--- 197

Query: 188 VYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVAL 247
              R    +  ++      C  CG        +G    E  H+IP S    D   N VAL
Sbjct: 198 ---RSSAFRQIVVPSYDYCCAICG--IRVITPEGRSAAEAAHIIPWSRSYNDDPRNGVAL 252

Query: 248 CPNCHRELHYS 258
           C   H      
Sbjct: 253 CGLHHWVFDQG 263


>UniRef50_C0GPK5 Restriction endonuclease n=1 Tax=Desulfonatronospira thiodismutans
           ASO3-1 RepID=C0GPK5_9DELT
          Length = 318

 Score = 76.8 bits (187), Expect = 8e-13,   Method: Composition-based stats.
 Identities = 24/111 (21%), Positives = 39/111 (35%), Gaps = 10/111 (9%)

Query: 148 LSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGIC 207
           L + ++++         L     + P GS KP  +        RD   +  ++      C
Sbjct: 159 LLEASENQQAYEYSRKLLKAAEKTLPYGSDKPANI--------RDQGFRKAVMTLYAHRC 210

Query: 208 ENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258
             CG        +G+  +E  H+ P S    D   N +ALC  CH      
Sbjct: 211 ALCGIRM--LTPEGHTIVEAAHIRPWSDTSDDRPANGMALCRLCHWSFDRG 259


>UniRef50_B8JBJ0 HNH endonuclease n=4 Tax=Anaeromyxobacter dehalogenans
           RepID=B8JBJ0_ANAD2
          Length = 357

 Score = 76.8 bits (187), Expect = 8e-13,   Method: Composition-based stats.
 Identities = 29/128 (22%), Positives = 49/128 (38%), Gaps = 7/128 (5%)

Query: 144 ELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDP-----MVKAW 198
            L +L     D++LL   V  L+ K   +  G  +  +  R      RDP      V+  
Sbjct: 213 RLRDLRPDLSDDALLEAAVDLLLAKAEKRKGGGARSSDRPRASVRPSRDPGYIPAHVRRE 272

Query: 199 ILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258
           + ++  G C+    N     +     L++ HV+P + GG  +  N   LC   + E    
Sbjct: 273 VWRRDGGCCQWRLANGEICGSTHA--LQLDHVVPRALGGESSVGNLRVLCAAHNLEAARR 330

Query: 259 KNAKELIE 266
                LI+
Sbjct: 331 VFGDALID 338


>UniRef50_Q7UQV2 Restriction endonuclease n=1 Tax=Rhodopirellula baltica
           RepID=Q7UQV2_RHOBA
          Length = 201

 Score = 76.4 bits (186), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 29/131 (22%), Positives = 49/131 (37%), Gaps = 9/131 (6%)

Query: 143 GELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQ 202
               ELSQ   D+        + +   +  P  +R     +R+    VR    +  +  +
Sbjct: 53  DSWCELSQLASDQKQPEDEYIQAVGFEMKVPRITRL-TRFDRMPAQTVR--FNRKNLFAR 109

Query: 203 SKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAK 262
               C+ CGK  P +       L + HV+P S GG  T +N V  C  C+         +
Sbjct: 110 DDHTCQYCGKAEPTHK------LSLDHVVPRSHGGGTTWENIVCCCLRCNSRKGGRTPQQ 163

Query: 263 ELIEMLYVNIN 273
             +++L   I 
Sbjct: 164 AHMKLLSRPIK 174


>UniRef50_A5V9C7 HNH endonuclease n=1 Tax=Sphingomonas wittichii RW1
           RepID=A5V9C7_SPHWW
          Length = 426

 Score = 76.0 bits (185), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 38/230 (16%), Positives = 78/230 (33%), Gaps = 10/230 (4%)

Query: 55  GVSQVVVYLASSSVRKHMHSLDERKIHPGEYFTLIGNSPRDIR--LKMCGYQAYFSRTGR 112
           G  +   ++ S      + SL     +  +  +   N  R  R  LK+    +Y      
Sbjct: 179 GAYRATGFVGSEDDAAFIGSLGNDSAYTVKGLSAPDNLRRQARESLKVLCQISYLHVVRD 238

Query: 113 KEIPSGNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQ 172
           +   +  R    +            A+    E+  L+      S L+             
Sbjct: 239 RVFINLARKDAEIAFGELNPIGGPRAANRDAEIRRLANLFTGGSTLDFFDYPETVIAEVV 298

Query: 173 PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGI-CENCGKNAPFYLNDGNPYLEVHHVI 231
             G  +  +V++      R+  ++      +    C+ C  +           +++HH++
Sbjct: 299 ESGFEEGNKVQKTHVTIERNSGLRKAFFAANPTTVCDVCNLDTARSYPWTERVMDLHHLL 358

Query: 232 PLSSG-----GADTTDNCVALCPNCHRELHY--SKNAKELIEMLYVNINR 274
           PLSSG        T D+ V LCP+CHR +H    +  +    + + + + 
Sbjct: 359 PLSSGTRVIGRGTTFDDLVPLCPSCHRAVHRYYGEWFRTTKRLDFHSRDE 408


>UniRef50_C4K5N9 Group II intron encoded reverse transcriptase n=10 Tax=Candidatus
           Hamiltonella defensa 5AT (Acyrthosiphon pisum)
           RepID=C4K5N9_HAMD5
          Length = 570

 Score = 76.0 bits (185), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 24/93 (25%), Positives = 36/93 (38%), Gaps = 14/93 (15%)

Query: 187 KVYVRDPMVKAW---------ILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGG 237
           + Y R+   +           + ++ KG C  C +       D    L VHH+ P + GG
Sbjct: 479 RDYWRNRQARKQPFIYGVKVNLYKRQKGYCPLCDQEL-----DNGEQLHVHHIQPKAEGG 533

Query: 238 ADTTDNCVALCPNCHRELHYSKNAKELIEMLYV 270
            +   N   L  NCHR+LH  K     +  L  
Sbjct: 534 DNKLANLRLLHANCHRQLHSKKRKNVEVSKLRE 566


>UniRef50_Q0RLC9 Putative uncharacterized protein n=1 Tax=Frankia alni ACN14a
           RepID=Q0RLC9_FRAAA
          Length = 502

 Score = 76.0 bits (185), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 30/132 (22%), Positives = 54/132 (40%), Gaps = 15/132 (11%)

Query: 137 WASIIRGE----LSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRD 192
           WA+++ G      +   QP   E L  +     +++ +  P G   P++V R  +     
Sbjct: 343 WAALLGGSGLPATTSWGQPLSREVLRRIACDASVRRIILDPAGV--PLDVGRAHRTV--T 398

Query: 193 PMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252
             ++  ++ +  G C   G + P        + E HH+     GG  + DN V LC   H
Sbjct: 399 ADIRQALIARDNG-CAFPGCDRPV------GWCEAHHIRHWIDGGHTSLDNSVLLCGYHH 451

Query: 253 RELHYSKNAKEL 264
           R +H+     +L
Sbjct: 452 RTVHHQGWTVQL 463


>UniRef50_C3XKK9 Restriction endonuclease n=1 Tax=Helicobacter winghamensis ATCC
           BAA-430 RepID=C3XKK9_9HELI
          Length = 400

 Score = 76.0 bits (185), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 37/195 (18%), Positives = 65/195 (33%), Gaps = 23/195 (11%)

Query: 92  SPRDIRLKMCGYQAYFS---RTGRKEIPSGNRTKRILINVPGIY-----SDSFWASIIRG 143
           + R+ + ++  Y            K + +            GIY       SF  +    
Sbjct: 183 NKRNAQFRINLYWYLCHIGLLNPYKALKASKAYNLDYKLDNGIYYFSCEEPSFTQNSFEE 242

Query: 144 ELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQS 203
            ++       D+ L    + K+ K    + E  ++          + RD  +       S
Sbjct: 243 RIAHYLHIIYDKHLSPYEIEKIRKDLAFEKENDKE---------SFSRDGQIVKIFKYSS 293

Query: 204 KGICENCG-----KNAPFYLNDGNPYLEVHHVIPLSSG-GADTTDNCVALCPNCHRELHY 257
             IC  C      ++  F    G  Y E+HH I +      D  +N   LCP CHR L  
Sbjct: 294 DDICAACNDYYDIQDRSFLTKMGRYYTEIHHCISVGKDKQLDVLENLTKLCPVCHRALKK 353

Query: 258 SKNAKELIEMLYVNI 272
             +++   + +  NI
Sbjct: 354 GASSESYQKQIINNI 368


>UniRef50_Q3EQP7 5-methylcytosine-specific restriction enzyme A n=1 Tax=Bacillus
           thuringiensis serovar israelensis ATCC 35646
           RepID=Q3EQP7_BACTI
          Length = 186

 Score = 76.0 bits (185), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 41/178 (23%), Positives = 66/178 (37%), Gaps = 18/178 (10%)

Query: 108 SRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIK 167
             TG K +   N     L N+     D     +   E +   Q      +    V  +I 
Sbjct: 2   ESTGEKVLNVTNPRSIFLTNISESLRDLIIEILRNPEANYQYQ------VEQENVGSVII 55

Query: 168 KTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLN-DGNPYLE 226
           + + +   S+   E       Y RD       +  +   CE    +  F        Y+E
Sbjct: 56  EDIPKNVPSKSKGE---GSGAYKRDFKTAKNAIVLANYKCEIDLNHEYFISKVTKRNYVE 112

Query: 227 VHHVIPLS-----SGGADTTDNCVALCPNCHRELHYSKNA--KELIEMLY-VNINRLQ 276
            HH+IP+          D   N ++LC  CH++LH+++    + LI+ LY   INRL 
Sbjct: 113 AHHLIPMGFQDDFQKSIDVEANIISLCAYCHKKLHHAEYKVIEPLIKKLYDARINRLN 170


>UniRef50_A1B3Q8 HNH endonuclease n=2 Tax=Rhodobacteraceae RepID=A1B3Q8_PARDP
          Length = 109

 Score = 76.0 bits (185), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 23/100 (23%), Positives = 39/100 (39%), Gaps = 9/100 (9%)

Query: 182 VERLQKVYVRDP---MVKAWILQQSKGI--CENCGKNA-PFYLNDGNPYLEVHHVIPLS- 234
           + R+     R+      K  +  +  G   CE CG +    Y   G  ++E HH +P+S 
Sbjct: 1   MTRVHVSRERNSTLVKKKKAVALRQHGCLACEVCGFDFLQTYGERGREFIECHHTLPISS 60

Query: 235 --SGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNI 272
               G     +   +C NCHR +H  +    + +     I
Sbjct: 61  LGEHGKTNLKDLALVCSNCHRMIHARRPWWSIDDAKAALI 100


>UniRef50_Q81E47 5-methylcytosine-specific restriction enzyme A n=15 Tax=Bacillus
           cereus group RepID=Q81E47_BACCR
          Length = 97

 Score = 76.0 bits (185), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 30/93 (32%), Positives = 49/93 (52%), Gaps = 8/93 (8%)

Query: 186 QKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDG-NPYLEVHHVIPLS-----SGGAD 239
           ++V+ RDP      ++Q++  CE    +  F        Y+E HH+IPL          D
Sbjct: 5   REVWPRDPKKAKQAIKQAEFKCEIDDTHETFVSEASRKNYMEAHHLIPLRMQHDFENSLD 64

Query: 240 TTDNCVALCPNCHRELHYS--KNAKELIEMLYV 270
              N V++CPNCHR +HY   K+ K+++E+L+ 
Sbjct: 65  VVGNIVSICPNCHRLIHYGRDKDKKKVLELLFE 97


>UniRef50_B9JB56 Putative uncharacterized protein n=1 Tax=Agrobacterium radiobacter
           K84 RepID=B9JB56_AGRRK
          Length = 219

 Score = 75.6 bits (184), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 24/79 (30%), Positives = 32/79 (40%), Gaps = 4/79 (5%)

Query: 182 VERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLS--SGGAD 239
            E      +RD ++   +       C+ CG      L DG  Y E HH+IPL     G D
Sbjct: 106 KEVTTNRIIRDTVMTCKVKALHHSKCQICGT--SISLPDGRAYSEAHHIIPLGAPHRGPD 163

Query: 240 TTDNCVALCPNCHRELHYS 258
              N + +CPN H  L   
Sbjct: 164 IPSNIIIVCPNHHAMLDLG 182


>UniRef50_D0C4R2 HNH endonuclease n=1 Tax=Acinetobacter sp. RUH2624
           RepID=D0C4R2_9GAMM
          Length = 298

 Score = 75.6 bits (184), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 36/156 (23%), Positives = 58/156 (37%), Gaps = 14/156 (8%)

Query: 130 GIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVY 189
           GI   + W + +  E   L +           V+ L         G  +     R   V 
Sbjct: 148 GIGQSNVWYAKLE-ETKPLVEKVKKYIEKYCLVNDLPDIDDL---GVTEGSLKIRRHLVR 203

Query: 190 VRDPMVKAWILQQ-----SKGICENCGKNAPF-YLNDGNPYLEVHHVIPLSSGG---ADT 240
            R+  +     Q+      K  CE C  +    Y   G  + EVHH+IPL+         
Sbjct: 204 ERNLSIIKQKKQKILSDFGKLECEVCHFDFEKNYGEIGKEFCEVHHLIPLNQSDSIVKTK 263

Query: 241 TDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQ 276
            ++   +C NCHR LH  +   E+ E L + +N++ 
Sbjct: 264 LEDLAIVCSNCHRMLHKGQPLLEIHE-LKMLLNKVN 298


>UniRef50_Q8DK67 Reverse transcriptase n=1 Tax=Thermosynechococcus elongatus BP-1
           RepID=Q8DK67_THEEB
          Length = 317

 Score = 75.2 bits (183), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 22/86 (25%), Positives = 41/86 (47%), Gaps = 5/86 (5%)

Query: 173 PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIP 232
           PE +    + ++L++   +    +  + ++  GIC  CG          +   E+HH++P
Sbjct: 224 PEWAEYFEQRKKLKEAPAQYRRTRRELWKKQGGICPVCGGEIE-----QDMLTEIHHILP 278

Query: 233 LSSGGADTTDNCVALCPNCHRELHYS 258
              GG D  DN V +  NCH+++H  
Sbjct: 279 KHKGGTDDLDNLVLIHTNCHKQVHSR 304


>UniRef50_B1XNN9 Restriction endonuclease n=20 Tax=Cyanobacteria RepID=B1XNN9_SYNP2
          Length = 166

 Score = 75.2 bits (183), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 23/95 (24%), Positives = 40/95 (42%), Gaps = 9/95 (9%)

Query: 177 RKPVEVERLQKVYVRD-PMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSS 235
              + +    KV  R+ P+ +  IL++ +  C+ C K            L + H+IP S 
Sbjct: 48  PTVIRLRHYIKVPYREIPLTRKNILERDRHTCQYCRKRGE--------QLTLDHIIPRSR 99

Query: 236 GGADTTDNCVALCPNCHRELHYSKNAKELIEMLYV 270
           GG D+ +N V  C  C+         +  +E+L  
Sbjct: 100 GGVDSWENLVTACMRCNVRKGNRTPKEAEMELLIQ 134


>UniRef50_B9ZDV6 HNH endonuclease n=1 Tax=Natrialba magadii ATCC 43099
           RepID=B9ZDV6_NATMA
          Length = 282

 Score = 75.2 bits (183), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 8/62 (12%)

Query: 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254
           ++   L++    C  CG +           L+ HH++P S+GG D  +N + LC  CH  
Sbjct: 62  LRQQTLRRDNYACTRCGADDRT--------LQAHHIVPRSAGGPDELENLLTLCRPCHGV 113

Query: 255 LH 256
           +H
Sbjct: 114 IH 115


>UniRef50_D1VPN1 HNH endonuclease n=1 Tax=Frankia sp. EuI1c RepID=D1VPN1_9ACTO
          Length = 449

 Score = 74.9 bits (182), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 34/138 (24%), Positives = 56/138 (40%), Gaps = 15/138 (10%)

Query: 124 ILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVE 183
           +L  V G+   S  A    G       P    +L  +     +   L   EG   P+E+ 
Sbjct: 279 VLTTVDGLLGRSGGAPATTGY----GLPLSRAALERLGCDADLTHILLSKEGM--PLELG 332

Query: 184 RLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDN 243
           R +++    P ++  ++ +  G C       P       P+ + HH++P S+ G  +  N
Sbjct: 333 RTRRIVP--PWLRRALVARDGG-CAFPQCPKP------APWADAHHIVPWSARGDTSLGN 383

Query: 244 CVALCPNCHRELHYSKNA 261
            V LCP  HR LH  + A
Sbjct: 384 TVLLCPFHHRVLHRGEWA 401


>UniRef50_A3UIJ5 Putative uncharacterized protein n=1 Tax=Oceanicaulis alexandrii
           HTCC2633 RepID=A3UIJ5_9RHOB
          Length = 183

 Score = 74.9 bits (182), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 27/150 (18%), Positives = 48/150 (32%), Gaps = 8/150 (5%)

Query: 126 INVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERL 185
           I++  I  D F      G    +    DD++             +++ +   +   V +L
Sbjct: 3   ISIRRIPDDEFALIWTAGYAEVIGANDDDQAPAQPLYQ------VAEEQAEFERPIVSQL 56

Query: 186 QKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCV 245
                RD +    +       C   G         G   +E  H+ P++S G DT  N +
Sbjct: 57  SNRPFRDRVFAQQVRNAYDARCAVTG--LKIINGGGRAEMEAAHIQPVASNGPDTVRNGL 114

Query: 246 ALCPNCHRELHYSKNAKELIEMLYVNINRL 275
           AL    H        + +    L     R+
Sbjct: 115 ALSRTVHWMFDRGLISVDDDFKLLKAKGRI 144


>UniRef50_A6FN65 HIT family protein n=5 Tax=root RepID=A6FN65_9RHOB
          Length = 332

 Score = 74.9 bits (182), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 34/168 (20%), Positives = 59/168 (35%), Gaps = 10/168 (5%)

Query: 101 CGYQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNM 160
                  S+    E+ + N   R+L     +        I   EL+  +    D   L  
Sbjct: 45  ALLSYDQSQVEYYELRTKNMVGRVLTANGVVQPIKSGRQITGYELNTAALTDHDRRELLA 104

Query: 161 RVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLND 220
              + +   LS+  G            V      V+  +L+++K  CE CG +       
Sbjct: 105 LCDQRLADFLSKRGGRVWQHRSSADGYVP---GSVRYEVLKRAKYRCELCGAHED----- 156

Query: 221 GNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEML 268
               L V H+IP + GG+D   N  +LC  C+      ++  +   +L
Sbjct: 157 -QAALHVDHIIPRARGGSDDISNFQSLCVTCNTSK-RDRDDTDFRAVL 202


>UniRef50_C7LPI3 Restriction endonuclease n=1 Tax=Desulfomicrobium baculatum DSM
           4028 RepID=C7LPI3_DESBD
          Length = 313

 Score = 74.9 bits (182), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 21/110 (19%), Positives = 39/110 (35%), Gaps = 2/110 (1%)

Query: 149 SQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICE 208
             P  ++ LL++  ++L     +       P   E+  +   RD   +  I++     C 
Sbjct: 147 FAPVLEKLLLDLANTQLSAFDYADILLRETPALYEKAVEKPARDQAFRRVIVKVYDHRCA 206

Query: 209 NCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258
            CG        D    ++  H+   +    D+  N +ALC  CH      
Sbjct: 207 LCG--IRIISPDSRTVVDAAHIKDWAVSHDDSPTNGLALCKLCHWTFDSG 254


>UniRef50_UPI0001C311B3 HNH endonuclease n=1 Tax=Conexibacter woesei DSM 14684
           RepID=UPI0001C311B3
          Length = 162

 Score = 74.9 bits (182), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 9/80 (11%)

Query: 184 RLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDN 243
           R+ +   R  + +  +  +    C+ CG             L V HVIP S GG  T DN
Sbjct: 58  RVPRDTHRRKITRRAVFARDDWTCQYCGSRGN---------LTVDHVIPRSKGGGSTWDN 108

Query: 244 CVALCPNCHRELHYSKNAKE 263
            VA C  C+R    S   + 
Sbjct: 109 IVASCAPCNRRKGDSLPNQA 128


>UniRef50_C5VAT3 HNH endonuclease n=3 Tax=Corynebacterium RepID=C5VAT3_9CORY
          Length = 1089

 Score = 74.9 bits (182), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 23/120 (19%), Positives = 43/120 (35%), Gaps = 7/120 (5%)

Query: 137 WASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVK 196
           W +     +  +      ES          ++     +   +  E   ++    R  + +
Sbjct: 492 WGAPKSVNIEHVRAAFMSESSARELDRDNQQRAKRNVKVVAEMQEKLGIEGRPSRADVWR 551

Query: 197 AWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLS-SGGADTTDNCVALCPNCHREL 255
              +Q+  G C  CG    F  +      E+ H+IP +  G  +T DN VA+C  C+   
Sbjct: 552 FQSIQRQNGKCAYCGAEISFKNS------EMDHIIPQAGEGSTNTRDNLVAVCRECNSSK 605


>UniRef50_B4CXI0 HNH nuclease n=1 Tax=Chthoniobacter flavus Ellin428
           RepID=B4CXI0_9BACT
          Length = 397

 Score = 74.9 bits (182), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 28/227 (12%), Positives = 69/227 (30%), Gaps = 24/227 (10%)

Query: 54  SGVSQVVVYLASSSVRKHMHSLDERKIHPGEYFTLIGNSPRDIRLKMCGYQAYFSRTGRK 113
             +  ++++LA     + + S + +      +  +I       R +              
Sbjct: 188 CSIYHILLHLAFPDRYEAIVSENHKTRIVSVFAHVIAEEAILDRERRISRIREKLYDSHG 247

Query: 114 EIPSGNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQP 173
                +R +R            ++  +   +   + + T  +      +++L      + 
Sbjct: 248 VTDDSDRKRR------------WFFYLEDVKPLWIGRKTRRDQRTASVMAEL---RDEED 292

Query: 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPL 233
            G  +   +        R   +      + +  C  C  +        +  ++ HH+ PL
Sbjct: 293 AGELEGERMGNTGYRLRRSGKLVLSAKMRDRFTCVACEFH------YDDQIVQAHHLDPL 346

Query: 234 SS---GGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277
           S           + + LCPNCH   HY      + +     +  L+K
Sbjct: 347 SERKQPEKTGLKDLITLCPNCHYIAHYLLRKSYVYKRKDGLVAELRK 393


>UniRef50_D2MHK7 HNH endonuclease n=3 Tax=Bacteria RepID=D2MHK7_9BACT
          Length = 171

 Score = 74.5 bits (181), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 31/158 (19%), Positives = 56/158 (35%), Gaps = 19/158 (12%)

Query: 101 CGYQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNM 160
                YF         +  + +  + +V        W  +         +   D + L  
Sbjct: 27  AALWHYFQSVIDWTQATFPKKRASMKSVA-------WGPL---YDEHHERDDLDPARLEA 76

Query: 161 RVSKLIKKTLSQPEGSRKPVEVERLQK---VYVRDPMVKAWILQQSKGICENCGKNAPFY 217
            V++L K      +    P  + R +K   +    P ++A   ++ +GIC  CG++    
Sbjct: 77  EVARLHKDDDVTKKPGIYPYVLTRDEKYLNIRAFTPTMRAAAYERQEGICPRCGEHFVL- 135

Query: 218 LNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHREL 255
                  +E  H+ P S GG    +NC  LC  C+R  
Sbjct: 136 -----GAMEADHIDPWSEGGKTAPENCQMLCRPCNRRK 168


>UniRef50_C7D6X3 Putative uncharacterized protein n=1 Tax=Thalassiobium sp. R2A62
           RepID=C7D6X3_9RHOB
          Length = 192

 Score = 74.5 bits (181), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 26/103 (25%), Positives = 45/103 (43%), Gaps = 11/103 (10%)

Query: 181 EVERLQKVYVRDPMVKAWILQQSKGICENCG----KNAPFYLNDGNPYLEVHH---VIPL 233
               L +   R P ++  +L++   IC+ C     K+  F     +  L++HH   +  L
Sbjct: 88  RRYILSRRIERAPSIRKEVLEKLPPICQACRLDPAKHYSFRGKIDHYPLDIHHSKPIQSL 147

Query: 234 SSGGADT---TDNCVALCPNCHRELHYSKNAKELIEMLYVNIN 273
           + G +      D+ + LCP CHR +H   +  +L E L   I 
Sbjct: 148 AEGESRRYRVPDDFMVLCPTCHRMIHKQSDPSDL-EALKSIIR 189


>UniRef50_Q2IJQ6 HNH endonuclease n=1 Tax=Anaeromyxobacter dehalogenans 2CP-C
           RepID=Q2IJQ6_ANADE
          Length = 322

 Score = 74.5 bits (181), Expect = 4e-12,   Method: Composition-based stats.
 Identities = 25/133 (18%), Positives = 44/133 (33%), Gaps = 18/133 (13%)

Query: 144 ELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRD--PMVKAWILQ 201
            L +L     D++LL   V  L+ K   +     +            R     V+  + +
Sbjct: 189 RLRDLRPDLSDDALLEAAVDLLLAKAEKRKGALTERPRASVRPSRDPRHIPAHVRREVWR 248

Query: 202 QSKGICE-------NCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254
           +  G C+        CG             L++ HV+PL+ GG  +  N   LC   +  
Sbjct: 249 RDGGCCQWRVASGEICGS---------THALQLDHVVPLALGGESSPGNLRVLCAAHNLL 299

Query: 255 LHYSKNAKELIEM 267
                    L++ 
Sbjct: 300 AARRVLGDALMDR 312


>UniRef50_Q8YYJ2 Alr0856 protein n=6 Tax=Cyanobacteria RepID=Q8YYJ2_ANASP
          Length = 181

 Score = 74.5 bits (181), Expect = 4e-12,   Method: Composition-based stats.
 Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 9/84 (10%)

Query: 179 PVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGA 238
            +++  +++ +   P+ +  IL++    C+ CG            +L + HVIP S GG+
Sbjct: 66  RLKITSVERTWKVPPVNRREILRRDHHSCQYCGSR---------KHLTLDHVIPRSRGGS 116

Query: 239 DTTDNCVALCPNCHRELHYSKNAK 262
            T DN VA C  C+        A+
Sbjct: 117 HTWDNVVAACERCNSRKGDRTPAE 140


>UniRef50_B4SCA5 HNH nuclease n=1 Tax=Pelodictyon phaeoclathratiforme BU-1
           RepID=B4SCA5_PELPB
          Length = 340

 Score = 74.5 bits (181), Expect = 4e-12,   Method: Composition-based stats.
 Identities = 31/119 (26%), Positives = 44/119 (36%), Gaps = 8/119 (6%)

Query: 142 RGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQ 201
             E  EL+Q      +    + +L     S  E      E+   +K Y RD    A I  
Sbjct: 203 EKEQEELAQFYKQAKIKEEILDELNNLQPSDSE------EIIVNKKTYKRDNKTIAQIKI 256

Query: 202 QSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKN 260
                C+ CG        D + Y+E  H+      G +T DN + LCPN H+E      
Sbjct: 257 LRDFKCQICGV--TITKKDRSKYIEAAHIKAKHQKGRETIDNIILLCPNHHKEFDLGDR 313


>UniRef50_D1S1E3 HNH nuclease n=1 Tax=Micromonospora aurantiaca ATCC 27029
           RepID=D1S1E3_9ACTO
          Length = 496

 Score = 74.1 bits (180), Expect = 5e-12,   Method: Composition-based stats.
 Identities = 28/126 (22%), Positives = 42/126 (33%), Gaps = 9/126 (7%)

Query: 138 ASIIRGELSELSQPTDDESLLNMRVSKL---IKKTLSQPEGSRKPVEVE-RLQKVYVRDP 193
           A + R   S+L + T    +           ++  L  P GS  P E +       VR  
Sbjct: 327 AILSRALTSDLDRATVLAQVGLAGYDSAAGTLEPDLLTPTGSGDPAERKLVTVDRIVRSS 386

Query: 194 MVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSS--GGADTTDNCVALCPNC 251
                + +     C+ CG            Y E  H+  L     G D   N + LCPN 
Sbjct: 387 RYAKAVKRLYDHRCQICGVRLATR---DGYYSEAAHIRGLGKPHDGTDDLSNLLCLCPNH 443

Query: 252 HRELHY 257
           H +  +
Sbjct: 444 HTQFDF 449


>UniRef50_Q3IBU7 Putative HNH endonuclease n=1 Tax=Pseudoalteromonas haloplanktis
           TAC125 RepID=Q3IBU7_PSEHT
          Length = 420

 Score = 74.1 bits (180), Expect = 5e-12,   Method: Composition-based stats.
 Identities = 24/72 (33%), Positives = 33/72 (45%), Gaps = 6/72 (8%)

Query: 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254
           VKA++LQ+    C+             N  L VHH +  S GG D   N +ALC  CH +
Sbjct: 184 VKAYVLQRDNYKCQ------SGRKTKHNAKLHVHHKVFRSQGGTDALSNLIALCETCHND 237

Query: 255 LHYSKNAKELIE 266
           LH  K   ++  
Sbjct: 238 LHVGKFELKVKR 249


>UniRef50_C6WMA3 HNH nuclease n=1 Tax=Actinosynnema mirum DSM 43827
           RepID=C6WMA3_ACTMD
          Length = 218

 Score = 74.1 bits (180), Expect = 5e-12,   Method: Composition-based stats.
 Identities = 28/119 (23%), Positives = 39/119 (32%), Gaps = 13/119 (10%)

Query: 142 RGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPM----VKA 197
           R            ES        L +    +  G         L  +  R P     V+ 
Sbjct: 109 RASWWWFEDAVYAESRGYRPADVLARVVAERARGEALAERTLLLTSLNPRHPRIPAEVRR 168

Query: 198 WILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELH 256
            + ++ +G C +CG         G   L   HV+PL+ GG  T  N   LC  C R  H
Sbjct: 169 AVFERDRGRCAHCG---------GATDLNYDHVVPLAEGGPSTVGNLRVLCRPCLRIAH 218


>UniRef50_C9RCK5 HNH endonuclease n=2 Tax=Ammonifex degensii KC4 RepID=C9RCK5_AMMDK
          Length = 459

 Score = 74.1 bits (180), Expect = 5e-12,   Method: Composition-based stats.
 Identities = 21/73 (28%), Positives = 31/73 (42%), Gaps = 8/73 (10%)

Query: 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254
           V+ ++L++    C  CGK            LEV HV+P S GG D   N    C  C++ 
Sbjct: 186 VREYLLEKYGRRCAYCGKENV--------PLEVDHVVPKSRGGTDRVSNLTLACRECNQA 237

Query: 255 LHYSKNAKELIEM 267
                  + L E+
Sbjct: 238 KGNKLPQEWLEEL 250


>UniRef50_Q2IGI7 HNH nuclease n=29 Tax=Anaeromyxobacter RepID=Q2IGI7_ANADE
          Length = 420

 Score = 73.7 bits (179), Expect = 6e-12,   Method: Composition-based stats.
 Identities = 25/123 (20%), Positives = 42/123 (34%), Gaps = 18/123 (14%)

Query: 139 SIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRD--PMVK 196
              R  LS        E++L   + +L+ +   +   + +P    R      R     V+
Sbjct: 239 EAARDALSHSMPGASRETILEAALDELLAERDRRKGLTARPQMKPRPSTRPGRHIPAHVR 298

Query: 197 AWILQQSKGIC-------ENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCP 249
             +  +  G C       E CG             LE+ H++P + GG  T DN    C 
Sbjct: 299 REVWARDGGRCTFVLASGECCGS---------THRLELDHIVPRACGGVSTVDNLRIRCK 349

Query: 250 NCH 252
             +
Sbjct: 350 GHN 352


>UniRef50_D2R238 HNH endonuclease n=4 Tax=Planctomycetaceae RepID=D2R238_9PLAN
          Length = 198

 Score = 73.7 bits (179), Expect = 6e-12,   Method: Composition-based stats.
 Identities = 21/111 (18%), Positives = 45/111 (40%), Gaps = 7/111 (6%)

Query: 164 KLIKKTLSQPEGSRKPVEVERLQKVYVRDPMV-KAWILQQSKGICENCGKNAPFYLNDGN 222
           +L  +++       + + +    K+  R+    +  + ++    C+ CG         G 
Sbjct: 62  ELYLQSVRSQMRVPEVIALRTFDKLPERNVSFSRRNLFKRDHYTCQYCGCQP------GM 115

Query: 223 PYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNIN 273
             L + HV+P S GGA + +NCV  C  C++        +  +++    I 
Sbjct: 116 HELTIDHVLPRSRGGASSWENCVLACVECNKRKADKLPDEARMKIRQKPIR 166


>UniRef50_D2R9B6 HNH endonuclease n=1 Tax=Pirellula staleyi DSM 6068
           RepID=D2R9B6_9PLAN
          Length = 220

 Score = 73.7 bits (179), Expect = 6e-12,   Method: Composition-based stats.
 Identities = 26/137 (18%), Positives = 49/137 (35%), Gaps = 17/137 (12%)

Query: 132 YSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVR 191
           Y  + W  I   +  E  +   D+ +  ++   L+ + +   +  R P    R       
Sbjct: 60  YDFTTWCEISEFQAQE--KRPHDDWVKAVQFEILVPRIIRLIDYDRIPEREVRYN----- 112

Query: 192 DPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNC 251
               +  I  +    C+ CGK  P         L + HV+P S GG  + +N V  C  C
Sbjct: 113 ----RRQIFARDGNKCQYCGKRLPVQQ------LSLDHVMPRSRGGESSWENVVCSCLTC 162

Query: 252 HRELHYSKNAKELIEML 268
           +         +  + ++
Sbjct: 163 NTRKGGRTPQEAHMNLM 179


>UniRef50_C9RBS6 HNH endonuclease n=4 Tax=Ammonifex degensii KC4 RepID=C9RBS6_AMMDK
          Length = 388

 Score = 73.7 bits (179), Expect = 7e-12,   Method: Composition-based stats.
 Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 10/63 (15%)

Query: 196 KAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHREL 255
           +  +L +    C  CG             L+ HH++P S GG DT +N V LC  CHR+L
Sbjct: 177 REKVLNRDG-ACVLCGSTRR---------LQRHHLVPRSKGGTDTPENQVLLCAECHRKL 226

Query: 256 HYS 258
           H  
Sbjct: 227 HAG 229


>UniRef50_B9I5Z1 Predicted protein n=7 Tax=Magnoliophyta RepID=B9I5Z1_POPTR
          Length = 272

 Score = 73.7 bits (179), Expect = 7e-12,   Method: Composition-based stats.
 Identities = 19/98 (19%), Positives = 40/98 (40%), Gaps = 9/98 (9%)

Query: 173 PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIP 232
           P   R P  ++ +++  ++  + +  IL +    C+ C              L + HV+P
Sbjct: 141 PAVLRVPHLLQVVKRRRIKSNLSRKNILYRDNYTCQYCSSREN---------LTIDHVLP 191

Query: 233 LSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYV 270
            + GG    +N VA C  C+ +       +  +++  V
Sbjct: 192 TARGGEWKWENLVAACAKCNSKKGQKTPEEANMKLSKV 229


>UniRef50_C3BJL8 Paclitaxel/taxanoid biosynthesis susceptibility protein TS1 n=1
           Tax=Bacillus pseudomycoides DSM 12442 RepID=C3BJL8_9BACI
          Length = 374

 Score = 73.3 bits (178), Expect = 8e-12,   Method: Composition-based stats.
 Identities = 25/87 (28%), Positives = 38/87 (43%), Gaps = 14/87 (16%)

Query: 196 KAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHREL 255
           + ++  +    C+ C K            L  HH+I   SGG+D  DN V +   CH++ 
Sbjct: 142 RYYVFTRDHYTCQICKKKG--------GILHTHHIIERCSGGSDMADNLVTVHEECHQKF 193

Query: 256 HYS------KNAKELIEMLYVNINRLQ 276
           H        K  K+  E  ++NI RLQ
Sbjct: 194 HQGTIKHIFKKPKQYKETAFMNILRLQ 220


>UniRef50_A9FIM4 HNH endonuclease family protein n=1 Tax=Sorangium cellulosum 'So ce
           56' RepID=A9FIM4_SORC5
          Length = 221

 Score = 73.3 bits (178), Expect = 8e-12,   Method: Composition-based stats.
 Identities = 20/97 (20%), Positives = 39/97 (40%), Gaps = 9/97 (9%)

Query: 177 RKPVEVERLQKVYVRDPMVK---AWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPL 233
           R P  +   +   +R P ++     ++ +    C+ C +  P         L + HV+P 
Sbjct: 101 RVPRVLHLRRYDRMRRPTIRLTRKNVMLRDTHQCQYCARRPPVRD------LNIDHVLPR 154

Query: 234 SSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYV 270
           S GG DT +N V  C  C+    +    +  + ++  
Sbjct: 155 SRGGEDTWENLVTACRTCNLRKGWRTPDEASMRLIRQ 191


>UniRef50_Q8YML8 Alr4915 protein n=2 Tax=Nostocaceae RepID=Q8YML8_ANASP
          Length = 313

 Score = 73.3 bits (178), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 25/135 (18%), Positives = 44/135 (32%), Gaps = 14/135 (10%)

Query: 144 ELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQS 203
           E+ +++Q   D  L     S  I    +   G RK           +R+   +  I++  
Sbjct: 151 EMLQINQSFQDADLATETSSGSINLDNNPKWGCRK---------AIIRNAFFRKTIVRVY 201

Query: 204 KGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKE 263
              C  CG             ++  H+ P +        N +ALC N H           
Sbjct: 202 DYKCAFCGLR--VTKAINQNIVDGAHIKPFAQFYDSRIHNGIALCKNHHWAFDRG--WFT 257

Query: 264 LIEMLYVNI-NRLQK 277
           + E   + +   LQ+
Sbjct: 258 VDEQYKIIVSKELQE 272


>UniRef50_B4UMG8 HNH endonuclease n=3 Tax=Anaeromyxobacter RepID=B4UMG8_ANASK
          Length = 387

 Score = 72.9 bits (177), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 30/148 (20%), Positives = 54/148 (36%), Gaps = 24/148 (16%)

Query: 133 SDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYV-R 191
           S+ F   + R  L +L     D++LL   V  L+ K   +     +       +     R
Sbjct: 241 SERFARKLER--LRDLRPDLSDDALLEAAVDLLLAKAEKRKGALTERPRAPATRPSRPGR 298

Query: 192 DP-----MVKAWILQQSKGICEN-------CGKNAPFYLNDGNPYLEVHHVIPLSSGGAD 239
           DP      V+  + ++  G C+        CG             L++ H++PL+ GGA 
Sbjct: 299 DPGRVPAHVRREVWRRDGGCCQWRLANGGACGS---------THALQLDHIVPLALGGAS 349

Query: 240 TTDNCVALCPNCHRELHYSKNAKELIEM 267
           T  N   LC   +     +     +++ 
Sbjct: 350 TVANLRLLCAAHNLLAARAVLGDAVMDR 377


>UniRef50_B0PAM8 Putative uncharacterized protein n=1 Tax=Anaerotruncus colihominis
           DSM 17241 RepID=B0PAM8_9FIRM
          Length = 330

 Score = 72.9 bits (177), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 20/114 (17%), Positives = 41/114 (35%), Gaps = 9/114 (7%)

Query: 148 LSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVR---DPMVKAWILQQSK 204
              PT  + +     +    + +   +      +   +   Y+R      +K  +L++  
Sbjct: 50  FYTPTGKKGIYGAFPNWAQHERVRDSKKKCPEPDDTSINDWYLRRFISKDMKRAVLERDN 109

Query: 205 GICENCGK------NAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252
             C  CGK      +   +L  G     + H+ P+  GG    +N   +CP C+
Sbjct: 110 MKCAVCGKYLTSCKDIERFLKLGQGLYHIDHIAPVLQGGRAAIENLRLICPECN 163


>UniRef50_A8H4Z7 HNH nuclease n=1 Tax=Shewanella pealeana ATCC 700345
           RepID=A8H4Z7_SHEPA
          Length = 289

 Score = 72.9 bits (177), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 17/74 (22%), Positives = 30/74 (40%), Gaps = 2/74 (2%)

Query: 186 QKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCV 245
           ++V  RDP  +  +L+     C  CG +    ++D +  LE  H+      G    +N +
Sbjct: 161 KQVQKRDPRFRKEVLRAYNYQCAVCGFD--LRMDDISVGLEAAHIKWKQFHGPCDVNNGL 218

Query: 246 ALCPNCHRELHYSK 259
            LC   H+      
Sbjct: 219 TLCALHHKAFDKGA 232


>UniRef50_Q82CY5 Putative uncharacterized protein n=1 Tax=Streptomyces avermitilis
           RepID=Q82CY5_STRAW
          Length = 177

 Score = 72.9 bits (177), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 31/122 (25%), Positives = 40/122 (32%), Gaps = 4/122 (3%)

Query: 140 IIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWI 199
           I      +       E L         +      +G + P       +  VRD  V   +
Sbjct: 5   IADLLDEQEELDLPQEQLEAAEGESEEESEEESSQGEKFPKTRAARIQRLVRDAAVSRNV 64

Query: 200 LQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSG--GADTTDNCVALCPNCHRELHY 257
                G C+ CG        DG PY E  H+ PL     G D   N + LCPNCH  L  
Sbjct: 65  KDLYGGECQACGLRLV--GPDGRPYSEGAHIRPLGKPHCGPDVEPNVLCLCPNCHVRLDI 122

Query: 258 SK 259
             
Sbjct: 123 GA 124


>UniRef50_B9PFL0 Predicted protein (Fragment) n=2 Tax=cellular organisms
           RepID=B9PFL0_POPTR
          Length = 197

 Score = 72.9 bits (177), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 27/139 (19%), Positives = 55/139 (39%), Gaps = 9/139 (6%)

Query: 130 GIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVY 189
            + +++ W S +    +   +    E+    +   L   ++   EG RK           
Sbjct: 59  ALKTNTNWTSFVEK-GNGGFERIYLENEGQEKPKYLDPDSIEAEEGYRKDSSRMTST--- 114

Query: 190 VRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADT-TDNCVALC 248
            RD  +     ++    C++C      Y  +    ++ HH+ P++ G  +T  ++ ++LC
Sbjct: 115 -RDRKLADARKKKDNYTCQSCKNQ---YFVNDKYVIDCHHLNPINLGKRNTRIEDLISLC 170

Query: 249 PNCHRELHYSKNAKELIEM 267
           P CHR  H       L E+
Sbjct: 171 PTCHRIAHTRLPPYSLKEL 189


>UniRef50_A6TQ34 Putative uncharacterized protein n=3 Tax=Firmicutes
           RepID=A6TQ34_ALKMQ
          Length = 290

 Score = 72.9 bits (177), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 22/82 (26%), Positives = 32/82 (39%), Gaps = 2/82 (2%)

Query: 189 YVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALC 248
             RDP  +  IL+  +  C  CG N    L +    +E  H+    +GG D  +N +ALC
Sbjct: 157 RHRDPKFREKILRAYEYKCAVCGFN--VRLGNNLIAVEAAHIKWHQAGGPDNENNGMALC 214

Query: 249 PNCHRELHYSKNAKELIEMLYV 270
              H+              L V
Sbjct: 215 VMHHKLFDRGVFTLTSSRKLLV 236


>UniRef50_Q82H00 Putative uncharacterized protein n=1 Tax=Streptomyces avermitilis
           RepID=Q82H00_STRAW
          Length = 515

 Score = 72.9 bits (177), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 19/83 (22%), Positives = 27/83 (32%), Gaps = 3/83 (3%)

Query: 180 VEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLS--SGG 237
                + +   RD  V+  +       C+ C     F       Y E  H+  L     G
Sbjct: 391 RRRAAIVQAQDRDSQVRRQVKVWYDNTCQFCRTKIEF-PAQPFSYSEGAHIQALGAPHNG 449

Query: 238 ADTTDNCVALCPNCHRELHYSKN 260
            D  +N + LCPNCH        
Sbjct: 450 PDRVENMLCLCPNCHIRFDMGGR 472


>UniRef50_B0MB74 Putative uncharacterized protein n=1 Tax=Anaerostipes caccae DSM
           14662 RepID=B0MB74_9FIRM
          Length = 255

 Score = 72.9 bits (177), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 19/87 (21%), Positives = 43/87 (49%), Gaps = 7/87 (8%)

Query: 192 DPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNC 251
              ++  + ++    C+ CG++AP      +  LEV H+ P+++GG +   N +  C +C
Sbjct: 8   SKKIRFEVFKRDSFTCQYCGRSAP------DVILEVDHINPVANGGDNDIMNLITSCRDC 61

Query: 252 HRELHYSKNAK-ELIEMLYVNINRLQK 277
           +R    ++ +  E I+     ++ L +
Sbjct: 62  NRGKGKTELSDSETIKKKKEQLDELNE 88


>UniRef50_A8L869 Restriction endonuclease-like protein n=2 Tax=Actinomycetales
           RepID=A8L869_FRASN
          Length = 304

 Score = 72.9 bits (177), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 19/84 (22%), Positives = 24/84 (28%), Gaps = 2/84 (2%)

Query: 188 VYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVAL 247
              R       +L+     C  CG +           +E  HV   S  G D   N VAL
Sbjct: 174 RRRRSATFAEQVLRVYAYCCAACGFDGRI--GTIPVGVEAAHVRWHSQHGPDDLANGVAL 231

Query: 248 CPNCHRELHYSKNAKELIEMLYVN 271
           C   H               L V+
Sbjct: 232 CSLHHTLFDLGVLGLTPDRELKVS 255


>UniRef50_B4U6J4 HNH endonuclease n=1 Tax=Hydrogenobaculum sp. Y04AAS1
           RepID=B4U6J4_HYDS0
          Length = 174

 Score = 72.9 bits (177), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 25/117 (21%), Positives = 48/117 (41%), Gaps = 7/117 (5%)

Query: 139 SIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAW 198
           +++    S L + T   ++L      +I+ T    +     ++   L K + ++   +  
Sbjct: 16  TLLDYRKSFLLEYTQRATVLEYHPEAVIRSTYRTYK-VPIVLKTNALSKTFYKNIPTRYN 74

Query: 199 ILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHREL 255
           +  +    C  CGK         +  + V H+IP+S GG  T DN V  C +C+   
Sbjct: 75  VYVRDNFTCGYCGK------VCDDSEITVDHIIPVSKGGKWTWDNLVTACESCNASK 125


>UniRef50_C3JTD3 HNH endonuclease (Fragment) n=3 Tax=Rhodococcus RepID=C3JTD3_RHOER
          Length = 260

 Score = 72.5 bits (176), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 16/69 (23%), Positives = 32/69 (46%), Gaps = 7/69 (10%)

Query: 196 KAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHREL 255
           +  +  +  G C   G   P      + + + HH++  + GG    DN + LC + HR +
Sbjct: 169 RRALAVRDGG-CAFPGCGTP------SGWCDAHHIVHWNDGGPTDLDNLILLCGHHHRTM 221

Query: 256 HYSKNAKEL 264
           H+++   E+
Sbjct: 222 HHTEWRVEI 230


>UniRef50_Q3ISZ2 Putative uncharacterized protein n=1 Tax=Natronomonas pharaonis DSM
           2160 RepID=Q3ISZ2_NATPD
          Length = 237

 Score = 72.5 bits (176), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 18/89 (20%), Positives = 31/89 (34%)

Query: 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPL 233
           E   +  +         R  +++  +L++    C+ CG        + +  LE H     
Sbjct: 2   ELEPRADKRRTRDGQGPRWRVIREEVLERDDYTCQRCGYEQEAESGEPSKRLEAHFADAH 61

Query: 234 SSGGADTTDNCVALCPNCHRELHYSKNAK 262
            S   +  D  V +C  CH  LH    A 
Sbjct: 62  GSPSLEQLDRLVTVCGPCHATLHGDDPAY 90


>UniRef50_C8WWQ2 HNH endonuclease n=27 Tax=Bacteria RepID=C8WWQ2_ALIAD
          Length = 427

 Score = 72.5 bits (176), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 23/83 (27%), Positives = 35/83 (42%), Gaps = 12/83 (14%)

Query: 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254
           V+ ++L++    C  CG             LE+ HVIP S GG+D   N V  C  C++ 
Sbjct: 189 VREYLLEKWGRKCAYCGAENV--------PLEIDHVIPRSRGGSDRVSNLVLACHRCNQA 240

Query: 255 LHYSKNAKELIEMLYVNINRLQK 277
                    + E L  +  RL +
Sbjct: 241 KANRP----VEEFLAHDQERLHR 259


>UniRef50_A1ZG09 Paclitaxel/taxanoid biosynthesis susceptibility protein TS1 n=5
           Tax=root RepID=A1ZG09_9SPHI
          Length = 453

 Score = 72.5 bits (176), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 26/116 (22%), Positives = 49/116 (42%), Gaps = 8/116 (6%)

Query: 144 ELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQS 203
            L E  Q     S + + V+    + +  P+   K  +    +  +     ++ ++L + 
Sbjct: 133 RLVEQVQDCLPVSGVVLEVANFDIQKIKNPDIEGKQYQKGEQEGFWN----IREYVLHRD 188

Query: 204 KGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSK 259
           K  C+N      +        L+VHH++  S GG DT +N + LC  CH   ++ K
Sbjct: 189 KHSCQNPDCKNKYKGK----ILQVHHIVFKSMGGGDTPNNLITLCTKCHTSANHKK 240


>UniRef50_Q306Z6 HNH endonuclease (Fragment) n=1 Tax=Arthrospira platensis
           RepID=Q306Z6_SPIPL
          Length = 135

 Score = 72.5 bits (176), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 21/82 (25%), Positives = 34/82 (41%), Gaps = 14/82 (17%)

Query: 187 KVYVRDPMV-----KAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTT 241
           + Y R P       +  I+++    C+ CG +           L + HVIP S GG DT 
Sbjct: 59  RRYARVPFKNIVLSRKNIVKRDASTCQYCGSHTD---------LTIDHVIPKSRGGPDTW 109

Query: 242 DNCVALCPNCHRELHYSKNAKE 263
           +N V  C +C+ +       + 
Sbjct: 110 ENLVTACNSCNHKKGNRTPKEA 131


>UniRef50_Q538B5 MnlI restriction endonuclease n=2 Tax=Moraxella nonliquefaciens
           RepID=Q538B5_MORNO
          Length = 386

 Score = 72.2 bits (175), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 34/195 (17%), Positives = 65/195 (33%), Gaps = 19/195 (9%)

Query: 88  LIGNSPRDIRLKMCG---YQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGE 144
           + G + R+ + ++     Y  +     +  +   N  K     +          + I   
Sbjct: 172 ITGENERNTQFRINLRYFYDNFSDDLAKINLFKSNILKHNANLIKTKNIAQESRTFIER- 230

Query: 145 LSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSK 204
           L+       +++     + +L K      + +              R+  +  ++     
Sbjct: 231 LNFYRDNVLNQTKTQHEIEQLRKNLGFIYDDTIDEKTT--------RNQGIVQYVRAYFP 282

Query: 205 GICENCGKNAPF------YLNDGNPYLEVHHVIPLSSGGA-DTTDNCVALCPNCHRELHY 257
             C  C            Y +    YLEVHHVI  +S    D  DN V +CP CHR L  
Sbjct: 283 DECACCKNQYNIKDRSFTYRHSDRYYLEVHHVISFASDRTLDQIDNLVKVCPTCHRALSK 342

Query: 258 SKNAKELIEMLYVNI 272
           ++  ++  + L   I
Sbjct: 343 NRADEQYQKELISEI 357


>UniRef50_D0UZ69 PCQ3_20 n=1 Tax=Streptomyces sp. W9 RepID=D0UZ69_9ACTO
          Length = 205

 Score = 72.2 bits (175), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 25/124 (20%), Positives = 40/124 (32%), Gaps = 11/124 (8%)

Query: 134 DSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVE--RLQKVYVR 191
           D     +    L  + +  D E       +  +      P            R  +    
Sbjct: 80  DRATKQLEERGLISVLRSKDPEHPGLHAPNTYVLLRHVPPGPGSTNRRTTSGRTPRSDSI 139

Query: 192 DPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNC 251
              V+  +L++    C  CG             L + HV+P+S GG+DTT N   LC  C
Sbjct: 140 SNRVRLEVLERDGNRCLTCGTRED---------LTMDHVVPVSRGGSDTTSNLQTLCRPC 190

Query: 252 HREL 255
           +   
Sbjct: 191 NSRK 194


>UniRef50_A0PZM8 HNH endonuclease domain protein n=3 Tax=Bacteria RepID=A0PZM8_CLONN
          Length = 299

 Score = 72.2 bits (175), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 19/65 (29%), Positives = 32/65 (49%), Gaps = 3/65 (4%)

Query: 194 MVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHR 253
            ++  I ++    C+ CG +     ++ N  LE+ H+IP+S GG  T  N   LC  C+R
Sbjct: 236 KLREKIKKRDNYTCQKCGLS---TRDEKNLLLEIDHIIPISKGGMSTEKNLQTLCWKCNR 292

Query: 254 ELHYS 258
           +    
Sbjct: 293 KKGAK 297


>UniRef50_A3PZ99 Putative uncharacterized protein n=14 Tax=Mycobacterium
           RepID=A3PZ99_MYCSJ
          Length = 440

 Score = 72.2 bits (175), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 20/85 (23%), Positives = 31/85 (36%), Gaps = 10/85 (11%)

Query: 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPL 233
           E   +P+   R  ++  R   ++  +  + +  C   G  A          L  HH+   
Sbjct: 302 ERDGQPIGTGRTTRLISR--RLRRALEYRDR-TCVVPGCGATRG-------LHAHHIQHW 351

Query: 234 SSGGADTTDNCVALCPNCHRELHYS 258
             GG    DN V +CP  HR  H  
Sbjct: 352 EDGGPTDLDNLVLVCPYHHRLHHRG 376


>UniRef50_A3Z7E0 HIT family protein n=6 Tax=Synechococcus RepID=A3Z7E0_9SYNE
          Length = 314

 Score = 72.2 bits (175), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 27/141 (19%), Positives = 51/141 (36%), Gaps = 10/141 (7%)

Query: 117 SGNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGS 176
             ++ +     V  +      ++ I      +      + L  +    L++    + +  
Sbjct: 35  DSSQIEYYTERVKRMVGRVMTSNGITSHAGGVYSLIGVDDLSEIERDALLQLCREKLDAF 94

Query: 177 RKPVEVERL-QKVYVRDP---MVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIP 232
           R     E    +   R      ++  +  ++KG CE CG +           LEV H+IP
Sbjct: 95  RLKRGDEVFAHRSRHRTAISGSIRYRVFTRAKGRCECCGAHE------HQAALEVDHIIP 148

Query: 233 LSSGGADTTDNCVALCPNCHR 253
            + GG+D   N  ALC  C+ 
Sbjct: 149 KNHGGSDDISNFQALCFRCNA 169


>UniRef50_B0JFS6 HNH endonuclease n=2 Tax=Cyanobacteria RepID=B0JFS6_MICAN
          Length = 147

 Score = 72.2 bits (175), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 6/85 (7%)

Query: 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254
           ++  + Q++   CE C  +  + +      L++ H+ PL+ GGA+T DN    C  C++ 
Sbjct: 8   LRQKVKQRAGNRCEYCLSHQDYIM----GRLQIDHIQPLAKGGANTEDNLCLACELCNQY 63

Query: 255 LHYSKNAKELIEMLYVNI--NRLQK 277
                 A +    + V++   RLQK
Sbjct: 64  KWTQTEAIDPKSEVLVSLFNPRLQK 88


>UniRef50_Q73WH9 Putative uncharacterized protein n=1 Tax=Mycobacterium avium subsp.
           paratuberculosis RepID=Q73WH9_MYCPA
          Length = 314

 Score = 71.8 bits (174), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 33/198 (16%), Positives = 65/198 (32%), Gaps = 13/198 (6%)

Query: 59  VVVYLASSSVRKHMHSLDERKIHPGEYFTLIGNSPRDIRLKMCGYQAYFSRTGRK-EIPS 117
           V+ Y    +   H+  ++      G+  T + ++  ++  +       F+      +   
Sbjct: 122 VMKYFGIKADEAHLAEVEN----LGDSITRLEDAVNNLAQREASITKSFNPPAFILKHYF 177

Query: 118 GNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSR 177
           G   K + + +  I                 S      +L    +  LI+    +    +
Sbjct: 178 GEFMKHVGVELSPIRVPYPVYVFEYVSAGGNSSQRTTVTLDTPAIDALIETLSQKIRWRK 237

Query: 178 KPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGG 237
                  L    +R+      I  +    C  C   +     + +  LEV H++P+S GG
Sbjct: 238 SAAGQRALMTSRLRNS-----IKVRDHYTCRYC---SVSLAAEPHLLLEVDHIVPISKGG 289

Query: 238 ADTTDNCVALCPNCHREL 255
             T DN   LC  C+R  
Sbjct: 290 MSTPDNLQTLCWRCNRTK 307


>UniRef50_B3EKH2 HNH endonuclease n=10 Tax=Chlorobiaceae RepID=B3EKH2_CHLPB
          Length = 172

 Score = 71.8 bits (174), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 20/92 (21%), Positives = 34/92 (36%), Gaps = 13/92 (14%)

Query: 179 PVEVERLQKVYVRDPMV-----KAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPL 233
           P+       V+VR P       +  I ++    C+ CG             L + H+ P 
Sbjct: 54  PLPSIVRLNVFVRVPYKHIMLTRKNIFRRDNFQCQYCGTCGT--------PLTIDHMTPR 105

Query: 234 SSGGADTTDNCVALCPNCHRELHYSKNAKELI 265
           S GG D+ +N V  C  C+ +       +  +
Sbjct: 106 SQGGEDSWENLVTACGPCNTKKGNRTPQEARM 137


>UniRef50_A4EXC6 Putative uncharacterized protein n=3 Tax=Rhodobacterales
           RepID=A4EXC6_9RHOB
          Length = 297

 Score = 71.8 bits (174), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 30/145 (20%), Positives = 51/145 (35%), Gaps = 3/145 (2%)

Query: 133 SDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRD 192
           SD  +A II   L+   +P     + N  +        ++     +P +    Q+ + RD
Sbjct: 118 SDQDFARIIDAGLAVKREPNAIPRVGNFNLETGFADEQAEYLHMSEPRDSVLTQRAF-RD 176

Query: 193 PMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252
                 +     G C   G         G P +E  H+IP+S+ G DT  N +AL    H
Sbjct: 177 RSFARQVKHAYGGRCSMSG--LELRNGGGRPEVEAAHIIPVSNSGPDTVSNGLALSGTVH 234

Query: 253 RELHYSKNAKELIEMLYVNINRLQK 277
                   +      + V    + +
Sbjct: 235 WMFDRGLISISDDREILVAKKAVDE 259


>UniRef50_C0XUG8 HNH endonuclease n=1 Tax=Corynebacterium lipophiloflavum DSM 44291
           RepID=C0XUG8_9CORY
          Length = 443

 Score = 71.8 bits (174), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 18/74 (24%), Positives = 30/74 (40%), Gaps = 8/74 (10%)

Query: 185 LQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNC 244
            Q  +V +   +A +L      C   G N          +L+VHH+   ++GG    +N 
Sbjct: 320 RQSRFVNNAQFRA-LLAVWGYECAMPGCN-------HTRFLQVHHIKEWANGGETNLENL 371

Query: 245 VALCPNCHRELHYS 258
           + LC  CH  +   
Sbjct: 372 IPLCSACHSRVTNG 385


>UniRef50_C7Q4G6 HNH endonuclease n=1 Tax=Catenulispora acidiphila DSM 44928
           RepID=C7Q4G6_CATAD
          Length = 552

 Score = 71.8 bits (174), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 23/83 (27%), Positives = 34/83 (40%), Gaps = 6/83 (7%)

Query: 192 DPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNC 251
              ++  IL++    C  CG  AP         L V HV+P++ GG D   N VA C  C
Sbjct: 4   SKRLRYEILRRDNHTCRYCGATAPTVP------LRVDHVVPVALGGTDDATNLVASCEPC 57

Query: 252 HRELHYSKNAKELIEMLYVNINR 274
           +     +     L+E    +  R
Sbjct: 58  NSGKTSTAPDSPLVEQAREDAMR 80


>UniRef50_B6AYM6 Restriction endonuclease n=2 Tax=Rhodobacterales RepID=B6AYM6_9RHOB
          Length = 205

 Score = 71.8 bits (174), Expect = 3e-11,   Method: Composition-based stats.
 Identities = 21/134 (15%), Positives = 43/134 (32%), Gaps = 6/134 (4%)

Query: 137 WASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVK 196
           W  +      E       + ++ ++  + ++   +        V   R           +
Sbjct: 39  WMPLSTWSWQEAMTAVLQDRVIQLKTYEDLEIHSATQTFEVPAVVCLRQYHKRQNAAFTR 98

Query: 197 AWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELH 256
             +  +    C+ CG   P         L   HV+P S  G  T +N VA C +C+    
Sbjct: 99  YNLFLRDGFRCQYCGAKKPAKD------LTFDHVLPRSRKGPATFENIVAACQSCNLRKS 152

Query: 257 YSKNAKELIEMLYV 270
                +  +++L  
Sbjct: 153 NRTPREAGMKLLRK 166


>UniRef50_A0ZAT3 Putative uncharacterized protein n=1 Tax=Nodularia spumigena
           CCY9414 RepID=A0ZAT3_NODSP
          Length = 394

 Score = 71.8 bits (174), Expect = 3e-11,   Method: Composition-based stats.
 Identities = 25/103 (24%), Positives = 45/103 (43%), Gaps = 6/103 (5%)

Query: 160 MRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQ-SKGICENCGKNAPFYL 218
           ++   L  + + +     +   V        R P ++     + +  +C+ C  N     
Sbjct: 258 VKPVALSTREIPEDIIFTEGRRVRVTHLRTERSPQLRRLFFSRNALPVCDMCSCNTRHRY 317

Query: 219 NDGNPYLEVHHVIPLSS-----GGADTTDNCVALCPNCHRELH 256
              +  LE+HH++PLSS     G   + ++ V LCPNCHR +H
Sbjct: 318 PWTDNLLEIHHLLPLSSAITVTGEGTSLEDVVGLCPNCHRSVH 360


>UniRef50_Q21AN9 HNH endonuclease n=1 Tax=Rhodopseudomonas palustris BisB18
           RepID=Q21AN9_RHOPB
          Length = 200

 Score = 71.8 bits (174), Expect = 3e-11,   Method: Composition-based stats.
 Identities = 24/97 (24%), Positives = 39/97 (40%), Gaps = 13/97 (13%)

Query: 184 RLQKVYVRDP---MVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADT 240
           R  K   R+      +  +L ++   C                 L++HH+  +S+GG D 
Sbjct: 2   REAKPRERENLPLKTRVIVLTETGYRCAVPTCR-------NILALDMHHIWEVSAGGTDD 54

Query: 241 TDNCVALCPNCHRELHYSKNAKE---LIEMLYVNINR 274
           + N +ALCP CH   H      E   + + + V I R
Sbjct: 55  SSNLIALCPTCHALYHRGTIKAESIYVYKSMIVAITR 91


>UniRef50_A2SMN0 Putative uncharacterized protein n=1 Tax=Methylibium petroleiphilum
           PM1 RepID=A2SMN0_METPP
          Length = 298

 Score = 71.4 bits (173), Expect = 3e-11,   Method: Composition-based stats.
 Identities = 26/128 (20%), Positives = 46/128 (35%), Gaps = 8/128 (6%)

Query: 155 ESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNA 214
           + +L+    + + + +    G     E E   +   RDP  +  +LQ  +  C  C  + 
Sbjct: 133 QRVLDAHFPETLHEDILAAVGLEVSEETESTTRRR-RDPNFRNAVLQAYQYRCAVCELDL 191

Query: 215 PFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHR-----ELHYSKNAKELIEMLY 269
                     LE  HV    + G D   N VALC   H+       H   + + L+    
Sbjct: 192 RIGSITVG--LEAAHVKWHQARGPDAVHNGVALCSLHHKLFDLGAFHIGADRRILVSEQV 249

Query: 270 VNINRLQK 277
              +R ++
Sbjct: 250 HGTSRFEE 257


  Database: uniref50.fasta
    Posted date:  Mar 8, 2010 10:38 AM
  Number of letters in database: 1,040,396,356
  Number of sequences in database:  3,077,464
  
Lambda     K      H
   0.313    0.122    0.344 

Lambda     K      H
   0.267   0.0374    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,487,893,578
Number of Sequences: 3077464
Number of extensions: 57532186
Number of successful extensions: 197561
Number of sequences better than 1.0e-01: 250
Number of HSP's better than  0.1 without gapping: 1034
Number of HSP's successfully gapped in prelim test: 1513
Number of HSP's that attempted gapping in prelim test: 194395
Number of HSP's gapped (non-prelim): 2675
length of query: 277
length of database: 1,040,396,356
effective HSP length: 127
effective length of query: 150
effective length of database: 649,558,428
effective search space: 97433764200
effective search space used: 97433764200
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 92 (40.2 bits)
