BLASTP 2.2.22 [Sep-27-2009]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= batch____
         (760 letters)

Database: uniref50.fasta 
           3,077,464 sequences; 1,040,396,356 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q2G1D8 Formate acetyltransferase n=978 Tax=cellular org...  1073   0.0  
UniRef50_B3DSM0 Pyruvate-formate lyase n=32 Tax=Bacteria RepID=B...   823   0.0  
UniRef50_C1N297 Predicted protein n=1 Tax=Micromonas pusilla CCM...   713   0.0  
UniRef50_B5I3J0 Truncated formate acetyltransferase n=8 Tax=Bact...   637   0.0  
UniRef50_B4U135 Pyruvate formate-lyase n=65 Tax=Bacilli RepID=B4...   612   e-173
UniRef50_O32799 Formate acetyltransferase n=32 Tax=Bacilli RepID...   601   e-170
UniRef50_Q2C4S5 Formate acetyltransferase n=7 Tax=Gammaproteobac...   408   e-112
UniRef50_D1NCN8 Formate C-acetyltransferase n=1 Tax=Haemophilus ...   258   8e-67
UniRef50_C6VIV4 Formate C-acetyltransferase n=25 Tax=Bacteria Re...   199   3e-49
UniRef50_B2ISH7 Formate acetyltransferase, putative n=59 Tax=Bac...   191   1e-46
UniRef50_P75793 Putative formate acetyltransferase 3 n=109 Tax=B...   180   2e-43
UniRef50_A0Q2M5 Pyruvate formate-lyase n=9 Tax=Bacteria RepID=A0...   179   3e-43
UniRef50_B1C5P6 Putative uncharacterized protein n=3 Tax=Bacteri...   173   2e-41
UniRef50_D1ARQ1 Pyruvate formate-lyase n=3 Tax=Bacteria RepID=D1...   169   3e-40
UniRef50_A6LQ73 Pyruvate formate-lyase n=6 Tax=Bacteria RepID=A6...   162   3e-38
UniRef50_O94132 Formate C-acetyltransferase (Fragment) n=2 Tax=P...   162   5e-38
UniRef50_A6TKL5 Pyruvate formate-lyase n=1 Tax=Alkaliphilus meta...   161   7e-38
UniRef50_B8FA81 Formate C-acetyltransferase n=1 Tax=Desulfatibac...   160   1e-37
UniRef50_B6FX97 Putative uncharacterized protein n=4 Tax=Firmicu...   160   3e-37
UniRef50_A8GF53 Pyruvate formate-lyase n=31 Tax=Bacteria RepID=A...   159   5e-37
UniRef50_B6FJR9 Putative uncharacterized protein n=1 Tax=Clostri...   158   1e-36
UniRef50_Q18AX8 Glycerol dehydratase n=8 Tax=Clostridium RepID=Q...   156   3e-36
UniRef50_B2TMN7 Formate C-acetyltransferase n=13 Tax=Bacteria Re...   153   2e-35
UniRef50_B8G188 Pyruvate formate-lyase n=1 Tax=Desulfitobacteriu...   152   4e-35
UniRef50_B0G487 Putative uncharacterized protein n=2 Tax=Clostri...   152   7e-35
UniRef50_C0QGR8 PflD1 n=1 Tax=Desulfobacterium autotrophicum HRM...   148   1e-33
UniRef50_D1AFQ7 Pyruvate formate-lyase n=3 Tax=Fusobacteriaceae ...   147   1e-33
UniRef50_C6A251 Pyruvate-formate lyase n=50 Tax=cellular organis...   147   1e-33
UniRef50_B5XXR3 Formate C-acetyltransferase 2 n=9 Tax=cellular o...   147   2e-33
UniRef50_B8FFL2 Formate C-acetyltransferase n=1 Tax=Desulfatibac...   143   2e-32
UniRef50_B2TJX0 Formate C-acetyltransferase n=9 Tax=Bacteria Rep...   143   3e-32
UniRef50_C7X781 Pyruvate formate-lyase n=3 Tax=Bacteroidales Rep...   142   4e-32
UniRef50_Q7NEY2 Glr3745 protein n=1 Tax=Gloeobacter violaceus Re...   141   1e-31
UniRef50_P32674 Formate acetyltransferase 2 n=80 Tax=Gammaproteo...   140   2e-31
UniRef50_O28823 Pyruvate formate-lyase 2 (PflD) n=1 Tax=Archaeog...   140   2e-31
UniRef50_C7N778 Pyruvate-formate lyase n=1 Tax=Slackia heliotrin...   136   2e-30
UniRef50_A5N4Z6 Predicted glycyl radical enzyme n=2 Tax=Clostrid...   135   6e-30
UniRef50_B8FHW6 Formate C-acetyltransferase n=2 Tax=Desulfobacte...   133   2e-29
UniRef50_C0C5J5 Putative uncharacterized protein n=1 Tax=Clostri...   132   4e-29
UniRef50_UPI00016BFDA6 pyruvate formate-lyase n=1 Tax=Epulopisci...   129   3e-28
UniRef50_A6TPN1 Formate C-acetyltransferase n=3 Tax=Clostridiace...   127   1e-27
UniRef50_C0W9F6 Formate C-acetyltransferase n=1 Tax=Acidaminococ...   126   3e-27
UniRef50_A9KN53 Pyruvate formate-lyase n=21 Tax=Bacteria RepID=A...   125   6e-27
UniRef50_B1EF41 Keto-acid formate acetyltransferase (Keto-acid f...   125   6e-27
UniRef50_Q1A666 Glycerol dehydratase n=8 Tax=Clostridiales RepID...   125   8e-27
UniRef50_A8MJE8 Formate C-acetyltransferase n=57 Tax=Bacteria Re...   123   3e-26
UniRef50_B0MIH0 Putative uncharacterized protein n=1 Tax=Anaeros...   122   4e-26
UniRef50_A8ZW07 Formate C-acetyltransferase n=2 Tax=Proteobacter...   122   5e-26
UniRef50_A5CZF4 Pyruvate-formate lyase n=1 Tax=Pelotomaculum the...   115   5e-24
UniRef50_Q30WU7 Formate C-acetyltransferase n=1 Tax=Desulfovibri...   115   7e-24
UniRef50_B8J0R1 Formate C-acetyltransferase n=9 Tax=Proteobacter...   114   1e-23
UniRef50_B8FDB2 Formate C-acetyltransferase n=1 Tax=Desulfatibac...   114   2e-23
UniRef50_D2LJ70 Formate C-acetyltransferase n=1 Tax=Rhodomicrobi...   110   2e-22
UniRef50_B8FEM4 Formate C-acetyltransferase n=5 Tax=Proteobacter...   110   2e-22
UniRef50_Q56EP5 Vs.6 n=5 Tax=unclassified T4-like viruses RepID=...   108   7e-22
UniRef50_A6CWD5 Formate acetyltransferase 2 n=4 Tax=Bacteria Rep...   108   8e-22
UniRef50_Q70BJ5 Putative uncharacterized protein n=4 Tax=Siphovi...   108   8e-22
UniRef50_B7UH18 Autonomous glycyl radical cofactor n=257 Tax=roo...   108   1e-21
UniRef50_D1NB06 Formate C-acetyltransferase n=1 Tax=Victivallis ...   107   2e-21
UniRef50_Q312S2 Formate C-acetyltransferase n=9 Tax=Bacteria Rep...   105   6e-21
UniRef50_B0NGB8 Putative uncharacterized protein n=3 Tax=Bacteri...   105   7e-21
UniRef50_B7BHI6 Putative uncharacterized protein (Fragment) n=1 ...   105   9e-21
UniRef50_Q5E2Y6 Autonomous glycyl radical cofactor n=6 Tax=Prote...   104   1e-20
UniRef50_Q6RHV7 Putative uncharacterized protein vs.6 n=1 Tax=Ae...   103   2e-20
UniRef50_B1BA70 HpdB protein n=1 Tax=Clostridium botulinum C str...   100   2e-19
UniRef50_C0CUZ2 Putative uncharacterized protein n=1 Tax=Clostri...   100   2e-19
UniRef50_A6CVH9 Formate C-acetyltransferase n=10 Tax=Bacteria Re...    99   8e-19
UniRef50_B8FMK7 Formate C-acetyltransferase n=1 Tax=Desulfatibac...    97   2e-18
UniRef50_D1ANR4 Formate C-acetyltransferase n=1 Tax=Sebaldella t...    97   3e-18
UniRef50_C6BT93 Formate C-acetyltransferase n=6 Tax=Desulfovibri...    97   3e-18
UniRef50_A6G8C6 Pyruvate formate-lyase 2 (PflD) n=1 Tax=Plesiocy...    94   2e-17
UniRef50_Q76Z52 Putative uncharacterized protein vs.6 n=1 Tax=Ae...    92   7e-17
UniRef50_D1N4L3 Formate C-acetyltransferase n=1 Tax=Victivallis ...    91   1e-16
UniRef50_C0VY69 Putative uncharacterized protein n=1 Tax=Actinom...    90   3e-16
UniRef50_A7VPJ9 Putative uncharacterized protein n=1 Tax=Clostri...    89   7e-16
UniRef50_C5EHI0 Pyruvate formate-lyase n=8 Tax=Bacteria RepID=C5...    87   3e-15
UniRef50_B0CLU5 Alpha-subunit of naphtylmethylsuccinate synthase...    86   5e-15
UniRef50_C0A3H6 Formate C-acetyltransferase n=1 Tax=Opitutaceae ...    79   9e-13
UniRef50_A7VW43 Putative uncharacterized protein n=1 Tax=Clostri...    77   4e-12
UniRef50_C6IIV1 Formate acetyltransferase 2 n=3 Tax=Bacteria Rep...    75   9e-12
UniRef50_D1N5W4 Formate C-acetyltransferase n=1 Tax=Victivallis ...    74   2e-11
UniRef50_D1N9D9 Formate C-acetyltransferase n=1 Tax=Victivallis ...    72   7e-11
UniRef50_B2V300 4-hydroxyphenylacetate decarboxylase, catalytic ...    70   3e-10
UniRef50_A5ZSK3 Putative uncharacterized protein n=1 Tax=Ruminoc...    67   3e-09
UniRef50_C7XCZ5 Formate acetyltransferase 2 n=2 Tax=Bacteria Rep...    67   3e-09
UniRef50_O26446 Formate acetyltransferase 2 n=1 Tax=Methanotherm...    62   9e-08
UniRef50_Q38HX4 4-hydroxyphenylacetate decarboxylase glycyl radi...    60   4e-07
UniRef50_Q4C1X2 Putative uncharacterized protein n=1 Tax=Crocosp...    55   1e-05
UniRef50_O94139 Formate C-acetyltransferase (Fragment) n=2 Tax=P...    52   1e-04
UniRef50_A5UFY3 Formate acetyltransferase n=1 Tax=Haemophilus in...    51   2e-04
UniRef50_UPI0001742832 Formate acetyltransferase n=1 Tax=candida...    48   0.001
UniRef50_Q39VF1 Formate C-acetyltransferase glycine radical:Pyru...    47   0.002
UniRef50_A6BGV7 Putative uncharacterized protein n=1 Tax=Dorea l...    47   0.004
UniRef50_D2T6G2 Autonomous glycyl radical cofactor n=1 Tax=Erwin...    46   0.006

>UniRef50_Q2G1D8 Formate acetyltransferase n=978 Tax=cellular organisms
           RepID=PFLB_STAA8
          Length = 749

 Score = 1073 bits (2774), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 503/760 (66%), Positives = 614/760 (80%), Gaps = 11/760 (1%)

Query: 1   MSELNEKLATAWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLWDKVME 60
           M E N+  ATAW+GF  G W   V+VR+FIQ NYT YEG++SFLAG TEAT+ LW++VM+
Sbjct: 1   MLETNKNHATAWQGFKNGRWNRHVDVREFIQLNYTLYEGNDSFLAGPTEATSKLWEQVMQ 60

Query: 61  GVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIKMIE 120
             K E       D DT VASTITSHDAGY++K LE IVG+QTE P KR++ PFGGI+M +
Sbjct: 61  LSKEERERGGMWDMDTKVASTITSHDAGYLDKDLETIVGVQTEKPFKRSMQPFGGIRMAK 120

Query: 121 GSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIG 180
            +C+AY  ELD   +KIFT+YRKTHNQGVFD Y+ ++L CRK+GV+TGLPDAYGRGRIIG
Sbjct: 121 AACEAYGYELDEETEKIFTDYRKTHNQGVFDAYSREMLNCRKAGVITGLPDAYGRGRIIG 180

Query: 181 DYRRVALYGIDYLMKDKLAQFTSLQADLENGVNLEQTIRLREEIAEQHRALGQMKEMAAK 240
           DYRRVALYG+D+LM++K+  F ++  ++      E  IRLREE++EQ+RAL ++KE+  K
Sbjct: 181 DYRRVALYGVDFLMEEKMHDFNTMSTEMS-----EDVIRLREELSEQYRALKELKELGQK 235

Query: 241 YGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQ 300
           YG+D+S PA N +EA+QW Y  YLAA+K QNGAAMS GRTSTFLD+Y ERDLKAG ITE 
Sbjct: 236 YGFDLSRPAENFKEAVQWLYLAYLAAIKEQNGAAMSLGRTSTFLDIYAERDLKAGVITES 295

Query: 301 EAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNT 360
           E QE++DH +MKLR+V+F RTP+Y+ELFSGDP W TESIGG+G+DGR LVTKNSFRFL++
Sbjct: 296 EVQEIIDHFIMKLRIVKFARTPDYNELFSGDPTWVTESIGGVGIDGRPLVTKNSFRFLHS 355

Query: 361 LYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNNDDYAIACC 420
           L  +GP+PEPN+T+LWS +LP NFK + AK+SI TSS+QYENDD+MR  +  DDY IACC
Sbjct: 356 LDNLGPAPEPNLTVLWSVRLPDNFKTYCAKMSIKTSSIQYENDDIMRESYG-DDYGIACC 414

Query: 421 VSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERM 480
           VS M +GKQMQFFGARANLAKT+LYAINGG DEK   QVGP  E I  +VL YDEV ++ 
Sbjct: 415 VSAMTIGKQMQFFGARANLAKTLLYAINGGKDEKSGAQVGPNFEGINSEVLEYDEVFKKF 474

Query: 481 DHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVAADSLSAI 540
           D  MDWLA  YI +LN+IHYMHDKYSYE   MALHD +++RTMA GIAGLSVAADSLSAI
Sbjct: 475 DQMMDWLAGVYINSLNVIHYMHDKYSYERIEMALHDTEIVRTMATGIAGLSVAADSLSAI 534

Query: 541 KYAKVKPIRDEDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIP 600
           KYA+VKPIR+E+GL +DFEIEG++P++GNND RVDD+AVDLVERFM K++   TYRD+  
Sbjct: 535 KYAQVKPIRNEEGLVVDFEIEGDFPKYGNNDDRVDDIAVDLVERFMTKLRSHKTYRDSEH 594

Query: 601 TQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYA 660
           T SVLTITSNVVYGKKTGNTPDGR+AG PF PGANPMHGRDQKGA++SL+SVAK+P+   
Sbjct: 595 TMSVLTITSNVVYGKKTGNTPDGRKAGEPFAPGANPMHGRDQKGALSSLSSVAKIPYDCC 654

Query: 661 KDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAM 720
           KDGIS TFSIVP +LGK+ E +  NL  ++DGY     +++ G HLN+NV NRE L+DAM
Sbjct: 655 KDGISNTFSIVPKSLGKEPEDQNRNLTSMLDGY-----AMQCGHHLNINVFNRETLIDAM 709

Query: 721 ENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQSM 760
           E+PE+YPQLTIRVSGYAV F  LT+EQQ DVI+RTF +SM
Sbjct: 710 EHPEEYPQLTIRVSGYAVNFIKLTREQQLDVISRTFHESM 749


>UniRef50_B3DSM0 Pyruvate-formate lyase n=32 Tax=Bacteria RepID=B3DSM0_BIFLD
          Length = 791

 Score =  823 bits (2126), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 420/778 (53%), Positives = 541/778 (69%), Gaps = 35/778 (4%)

Query: 9   ATAWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLWDKVMEGVKLENRT 68
           A AW GFT+G+WQ +++VRDFIQKNYTPYEGDE+FLA ATE T  LW  + +      R 
Sbjct: 16  AKAWAGFTEGNWQKDIDVRDFIQKNYTPYEGDETFLAPATEKTKHLWKYLDDNYLAVERK 75

Query: 69  HAPVDFDTAVASTITSHDAGYINK-QLEKIV-GLQTEAPLKRALIPFGGIKMIEGSCKAY 126
               D DT   + + +  AGYI+  +++ +V GLQT+ P KRA++P GG +M+E + K  
Sbjct: 76  QRVYDVDTHTPADVDAFPAGYIDSPEVDNVVVGLQTDVPCKRAMMPNGGWRMVEQAIKEA 135

Query: 127 NRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVA 186
            +E DP IKKIFT+YRKTHN GVF VYT  I   R + +LTGLPDAYGRGRIIGDYRRVA
Sbjct: 136 GKEPDPEIKKIFTKYRKTHNDGVFGVYTKQIKVARHNKILTGLPDAYGRGRIIGDYRRVA 195

Query: 187 LYGIDYLM--KDKLAQFTSLQADLENGVNLEQTIRLREEIAEQHRALGQMKEMAAKYGYD 244
           LYG++ L+  K +       + D      +E  IR REE  EQ +AL ++  +  +YG D
Sbjct: 196 LYGVNKLIAFKKRDKDSVPYRNDFTE-PEIEHWIRFREEHDEQIKALKKLINLGNEYGLD 254

Query: 245 ISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQE 304
           +S PA  AQEA+QWTY GYLA++KSQ+GAAMSFGR S FLD YIERDL+AGKITE +AQE
Sbjct: 255 LSRPAQTAQEAVQWTYMGYLASIKSQDGAAMSFGRNSAFLDCYIERDLQAGKITETDAQE 314

Query: 305 MVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYT- 363
           ++D++VMKLR+VRFLRT +YD +FSGDP WAT S  G G DGR++VTK SFR LNTL   
Sbjct: 315 LIDNIVMKLRIVRFLRTKDYDSIFSGDPYWATWSDAGFGDDGRSMVTKTSFRLLNTLTLE 374

Query: 364 -MGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNNDDYAIACCVS 422
            +GP PEPN+TI W  KLP  +K+F AK+SIDTS++QYE+D  +R  +  DD AIACCVS
Sbjct: 375 HLGPGPEPNITIFWDPKLPEAYKRFCAKISIDTSAIQYESDKEIRSHW-GDDAAIACCVS 433

Query: 423 PMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKS--EPIKGD---VLNYDEVM 477
           PM VGKQMQFF AR N AK +LYAINGG DE   MQV  K   EPI  +    L+Y++V 
Sbjct: 434 PMRVGKQMQFFAARVNSAKALLYAINGGRDEMTGMQVIDKGVIEPITPEADGTLDYEKVK 493

Query: 478 ERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVAADSL 537
              +  ++WL++ Y+ ALNIIHYMHDKY+YE+  MALHD++V RT+ CG++GLS+AADSL
Sbjct: 494 NNYEKALEWLSETYVMALNIIHYMHDKYAYESIEMALHDKEVYRTLGCGMSGLSIAADSL 553

Query: 538 SAIKYAKVKPIRDEDG-----------------LAIDFEIEGEYPQFGNNDPRVDDLAVD 580
           +A+KYAKV PI ++D                  L + +  EGE+P +GN+D R DD+A  
Sbjct: 554 AAVKYAKVYPIYNKDAKTLEGHEYEYVEGADDDLIVGYRTEGEFPVYGNDDDRADDIAKW 613

Query: 581 LVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGR 640
           +V   M ++++L  YR A+PTQS+LTITSNV YGK TG+ P G   G P+ PGANP +G 
Sbjct: 614 VVSTVMGQVKRLPVYRGAVPTQSILTITSNVEYGKNTGSFPSGHAKGTPYAPGANPENGM 673

Query: 641 DQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASI 700
           D  G + S+ SV K+ +  A DGIS T +I P+ LG+D++ R  NL G++D    H    
Sbjct: 674 DSHGMLPSMFSVGKIDYNDALDGISLTNTITPDGLGRDEDERIGNLVGILDAGNGH---- 729

Query: 701 EGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQ 758
            G  H N+NV+ +E + DA+E+PEKYP LT+RVSGYAV F  LTKEQQ DVI+RTF Q
Sbjct: 730 -GLYHANINVLRKETMEDAVEHPEKYPHLTVRVSGYAVNFVKLTKEQQLDVISRTFHQ 786


>UniRef50_C1N297 Predicted protein n=1 Tax=Micromonas pusilla CCMP1545
           RepID=C1N297_9CHLO
          Length = 776

 Score =  713 bits (1841), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 388/771 (50%), Positives = 507/771 (65%), Gaps = 43/771 (5%)

Query: 23  EVNVRDFIQKNYTPYEGDESFLAGA----TEATTTLWDKVMEGVKLENRTHAPVDFDTAV 78
            ++V  F+  N TP + D S L GA    TE TT LW    E +  E      +  D   
Sbjct: 8   RLDVAAFVAANVTPCDDDLSKLPGALADATEKTTKLWSLCRELLTQEFDAGV-LAIDATT 66

Query: 79  ASTITSHDAGYINKQ--LEKIV-GLQTEAPLKRALIPFGGIKMIEGSCKAYNRELDPMIK 135
            S++ SHDAGYI+    L+ +V GLQT APL R + P GG+++++ +   +  ELD  + 
Sbjct: 67  PSSVLSHDAGYIDGDGVLDDVVPGLQTSAPLVRGIKPLGGMRLVKRALAEHGVELDADVA 126

Query: 136 KIFTE-YRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLM 194
             F   +R+THN  VFD+YT ++   R+  ++TGLPDAYGRGR+IGDYRRVALYG+D + 
Sbjct: 127 AFFDRGWRRTHNDCVFDLYTQEMRLARRHHLVTGLPDAYGRGRVIGDYRRVALYGVDAIA 186

Query: 195 KDKLAQFTSLQADLENGV---------NLEQTIRLREEIAEQHRALGQMKEMAAKYGYDI 245
           + K A    L  +  +           ++  T R R+E+A + +AL  +K MAA+YG D+
Sbjct: 187 ETKRADAARLAEEASSTAAAAAAGGDGDVSATFRRRDELALELKALEALKTMAARYGADV 246

Query: 246 SGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEM 305
           S PA+NA+EA++WTY  +LAA K  +GAA+S GR   F DVYIERDL+ G + E +AQE+
Sbjct: 247 SRPASNAREAVRWTYLAFLAACKENDGAAISLGRLDAFFDVYIERDLRGGVMDESDAQEL 306

Query: 306 VDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRT------------LVTKN 353
           +DH V+KLR++R LR   YDE+F+GDP+WAT +I G    G              LVTK 
Sbjct: 307 IDHFVIKLRLIRQLRPKAYDEIFAGDPVWATCAIAGESSRGGGGGGAAAAAESRHLVTKT 366

Query: 354 SFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNND 413
           S+RF+ +L  +G +PEPNMT+LWS  LP  FK+  A+ SIDTSS+QY ND L+R  F +D
Sbjct: 367 SWRFMRSLANLGAAPEPNMTVLWSPTLPSGFKRQCARTSIDTSSVQYINDGLLRRAFKSD 426

Query: 414 DYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKS--EPIKGDV- 470
           D AIACCVS   +G   QFFGAR NLAK +L A+NGG++E    +V P S    + G + 
Sbjct: 427 DVAIACCVSGTRLGVDAQFFGARCNLAKLLLLALNGGLEELSGARVAPASIEASLGGGIA 486

Query: 471 ----LNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACG 526
               L YD+V  R+D +MDWLA  Y   + +IH+ HD+Y YEA++ +L D D    MA G
Sbjct: 487 PNVPLRYDDVRRRLDAYMDWLATLYRDVMALIHWSHDRYCYEAAIFSLIDTDRHYYMAYG 546

Query: 527 IAGLSVAADSLSAIKYAKVKPIRD-EDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERF 585
           +AGLSV  DSLSAIK+AKV P+ D E GL   FE EG +P +GN+D  VD +AVD+V  F
Sbjct: 547 VAGLSVVVDSLSAIKHAKVTPMLDAETGLIASFETEGTFPAYGNDDDAVDAIAVDVVTSF 606

Query: 586 MKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGA 645
           M K++ L  YRDA PT SVLTITSNV+YGK TG TPDGR AGAPF PGANPMHGRD  GA
Sbjct: 607 MNKLRALSQYRDAEPTLSVLTITSNVMYGKHTGATPDGRPAGAPFAPGANPMHGRDASGA 666

Query: 646 VASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQH 705
           ++SL SVAK+P+A+ KDGIS TFSI   +LGK  + R  NLA L+DGYF       G QH
Sbjct: 667 LSSLNSVAKVPYAHCKDGISNTFSIPGPSLGKTPDARVDNLAALLDGYFD-----RGAQH 721

Query: 706 LNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTF 756
           LNVNV++RE L+DAM +P KYP LT+RVSGYAV FN L++E Q++VI RTF
Sbjct: 722 LNVNVLSRETLIDAMNDPMKYPNLTVRVSGYAVNFNRLSREHQEEVIARTF 772


>UniRef50_B5I3J0 Truncated formate acetyltransferase n=8 Tax=Bacteria
           RepID=B5I3J0_9ACTO
          Length = 680

 Score =  637 bits (1643), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 312/540 (57%), Positives = 387/540 (71%), Gaps = 13/540 (2%)

Query: 5   NEKLAT-AWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLWDKVMEGVK 63
           +++ AT AW GF    W+  V+VRDFIQ N+TPYEGD SFL G T+ T  +W+ V   + 
Sbjct: 145 DDRTATDAWRGFAGTGWRERVDVRDFIQANFTPYEGDASFLTGPTDRTRAVWETV-SALF 203

Query: 64  LENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIKMIEGSC 123
            E R+   +D DTA  STITSH  GYI++  E IVGLQT+APLKRA++P GG++M+E   
Sbjct: 204 PEERSRGVLDVDTATPSTITSHAPGYIDRDRELIVGLQTDAPLKRAIMPNGGLRMVENGL 263

Query: 124 KAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYR 183
           +AY  E DP + ++F  YRKTHN GVFD YTP++   RK+G++TGLPDAYGRGRIIGDYR
Sbjct: 264 EAYGYEPDPFVTRVFGTYRKTHNDGVFDAYTPEMRAARKAGIITGLPDAYGRGRIIGDYR 323

Query: 184 RVALYGIDYLMKDKLAQFTSLQADLENGVNLEQTIRLREEIAEQHRALGQMKEMAAKYGY 243
           RVALYG D L++ K A+    +A L+   +    IR REE+AEQ RALG++ EMAA YG 
Sbjct: 324 RVALYGTDRLIEAKRAE----RALLDVRPSTADVIRDREELAEQTRALGELSEMAATYGC 379

Query: 244 DISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQ 303
           D+S PAT A EA+QW Y GYLAAVK QNGAAMS GRTSTFLDVY+ RDL  G I E  AQ
Sbjct: 380 DVSRPATTAHEAVQWLYLGYLAAVKEQNGAAMSLGRTSTFLDVYLRRDLTDGLIDESRAQ 439

Query: 304 EMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYT 363
           E++D  V+KLR+VRFLRTPEYD LFSGDP W TESIGGMG DGRTLVT+ SFRFL TLY 
Sbjct: 440 ELIDDFVIKLRIVRFLRTPEYDALFSGDPTWVTESIGGMGADGRTLVTRTSFRFLQTLYN 499

Query: 364 MGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNNDDYAIACCVSP 423
           +GP+PEPN+T+LWS +LP  FK+F A+VSIDTS++QYE+DDL RP    DD AIACCVS 
Sbjct: 500 LGPAPEPNLTVLWSPRLPTGFKEFCAQVSIDTSAVQYESDDLTRPR-TGDDTAIACCVSA 558

Query: 424 MIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHF 483
           M VG+QMQFFGAR NLAK +LYA+NGG DE    Q+ P + P+ G+ L+YDE+    D  
Sbjct: 559 MAVGRQMQFFGARVNLAKALLYAVNGGRDEMTGDQIAPPTPPLTGEYLDYDELSAAYDRV 618

Query: 484 MDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVAADSLSAIKYA 543
           +DWLAK Y+ ALN+IH     ++ +  L A  D    RT  C  A   VA+ +  + + A
Sbjct: 619 LDWLAKTYVDALNVIHL----HARQVRLRARGD-GAARTTPC-TASWPVASPACRSPRTA 672


>UniRef50_B4U135 Pyruvate formate-lyase n=65 Tax=Bacilli RepID=B4U135_STREM
          Length = 795

 Score =  612 bits (1579), Expect = e-173,   Method: Compositional matrix adjust.
 Identities = 334/769 (43%), Positives = 464/769 (60%), Gaps = 39/769 (5%)

Query: 11  AWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLWDKVMEGVKLE-NRTH 69
           AWEGF   DW+ + ++  F+Q NYTPY+GDESFLAG TE +  +  K++E  K     T 
Sbjct: 35  AWEGFKGTDWKEKASISRFVQANYTPYDGDESFLAGVTERSLHI-KKIIEETKAHYEATR 93

Query: 70  APVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIKMIEGSCKAYNRE 129
            P D      ++I    AG+I+K  E I G+Q +   K   +P GGI+M E + K    E
Sbjct: 94  FPYD---TRPTSIADIPAGFIDKDKELIFGIQNDELFKLNFMPKGGIRMAETTLKENGYE 150

Query: 130 LDPMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYG 189
            DP + +IFT++  T N G+F  YT +I R R +  +TGLPDAY RGRIIG Y R+ALYG
Sbjct: 151 PDPAVHEIFTKHVTTVNDGIFRAYTSNIRRARHAHTVTGLPDAYSRGRIIGVYARLALYG 210

Query: 190 IDYLMKDKLAQFTSL-QADLENGVNLEQTIRLREEIAEQHRALGQMKEMAAKYGYDISGP 248
            DYLM++K+  + ++ + D       E++IRLREEI  Q++ALG++ ++   YG D+  P
Sbjct: 211 ADYLMQEKVNDWNAITEID-------EESIRLREEINLQYQALGEVVKLGDLYGVDVRRP 263

Query: 249 ATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDH 308
           A N +EAIQW    ++A  +  NGAA S GR    LD++ ERDL  G  TE E QE VD 
Sbjct: 264 AENVKEAIQWVNIAFMAVCRVINGAATSLGRVPIVLDIFAERDLARGTFTESEIQEFVDD 323

Query: 309 LVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSP 368
            V+KLR V+F RT  YD L+SGDP + T S+ GMG DGR  VTK  +RFLNTL  +G SP
Sbjct: 324 FVLKLRTVKFARTKAYDALYSGDPTFITTSMAGMGNDGRHRVTKMDYRFLNTLDNIGNSP 383

Query: 369 EPNMTILWSEKLPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNNDDYAIACCVSPMIVGK 428
           EPN+T+LW++KLP  F+++   +S   SS+QYE    M  D   +   I+CCVSP+    
Sbjct: 384 EPNLTVLWTDKLPYAFRRYCMHMSHKHSSIQYEGVTTMAKDGYGEMSCISCCVSPLDPEN 443

Query: 429 Q-----MQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHF 483
           +     +Q+FGAR N+ K +L  +NGG D+  K       +P+  DVL++D V    +  
Sbjct: 444 EEQRHNIQYFGARVNVLKALLTGLNGGYDDVHKDYKVFDIDPVTDDVLDFDTVKANFEKS 503

Query: 484 MDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVAADSLSAIKYA 543
           +DWL   Y+ ALNIIHYM DKY+YEA  MA         M  GI G +   D+LSAIKYA
Sbjct: 504 LDWLTDTYVDALNIIHYMTDKYNYEAVQMAFLPSHQRANMGFGICGFANTVDTLSAIKYA 563

Query: 544 KVKPIRDEDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQS 603
            VKPIRDEDG   D+E  G+YP++G +DPR ++LA  L+E +  +++    Y++A  T S
Sbjct: 564 TVKPIRDEDGYIYDYETIGDYPRWGEDDPRSNELAEWLIEAYTTRLRSHKLYKNAEATVS 623

Query: 604 VLTITSNVVYGKKTGNTP---------DGRRAGAP---FGPGANPMHGRDQKGAVASLTS 651
           +LTITSNV Y K+TGN+P         DG    +    F PGANP + + + G + +L S
Sbjct: 624 LLTITSNVAYSKQTGNSPVHRGVYLNEDGTTNLSQLEFFSPGANPSN-KAKGGWLQNLNS 682

Query: 652 VAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVM 711
           +A L F+YA DGIS T  + P ALGK  + +  NL  ++DGYF +     GGQH+N+NVM
Sbjct: 683 LASLDFSYAADGISLTTQVSPRALGKTHDEQVENLVTILDGYFEN-----GGQHVNLNVM 737

Query: 712 NREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQSM 760
           +   + D +   E    + +R+SGY V    LT EQ+ ++  R F + +
Sbjct: 738 DLNDVYDKIMAGE---DVIVRISGYCVNTKYLTPEQKTELTQRVFHEVL 783


>UniRef50_O32799 Formate acetyltransferase n=32 Tax=Bacilli RepID=PFL_LACLM
          Length = 787

 Score =  601 bits (1549), Expect = e-170,   Method: Compositional matrix adjust.
 Identities = 330/774 (42%), Positives = 469/774 (60%), Gaps = 36/774 (4%)

Query: 11  AWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLWDKVMEGVKLENRTHA 70
           AW+GF   +W+++ +V  F+Q+NY PY+GDESFLAG TE T  +  K++E  K  +    
Sbjct: 13  AWDGFKGTNWRDKASVTRFVQENYKPYDGDESFLAGPTERTLKV-KKIIEDTK-NHYEEV 70

Query: 71  PVDFDTAVASTITSHDAGYIN---KQLEKIVGLQTEAPLKRALIPFGGIKMIEGSCKAYN 127
              FDT   ++I    AGYI+   K+LE I G+Q     +   +P GG+++ E     + 
Sbjct: 71  GFPFDTDRVTSIDKIPAGYIDANDKELELIYGMQNSELFRLNFMPRGGLRVAEKILTEHG 130

Query: 128 RELDPMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVAL 187
             +DP +  + ++   + N G+F  YT  I + R +  +TGLPDAY RGRIIG Y R+AL
Sbjct: 131 LSVDPGLHDVLSQTMTSVNDGIFRAYTSAIRKARHAHTVTGLPDAYSRGRIIGVYARLAL 190

Query: 188 YGIDYLMKDKLAQFTSLQADLENGVNLEQTIRLREEIAEQHRALGQMKEMAAKYGYDISG 247
           YG DYLMK+K  ++ ++       +N +  IRL+EEI  Q++AL ++    A YG D+S 
Sbjct: 191 YGADYLMKEKAKEWDAITE-----IN-DDNIRLKEEINMQYQALQEVVNFGALYGLDVSR 244

Query: 248 PATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVD 307
           PA N +EAIQW    Y+A  +  NGAA S GR    LD++ ERDL  G  TEQE QE VD
Sbjct: 245 PAMNVKEAIQWVNIAYMAVCRVINGAATSLGRVPIVLDIFAERDLARGTFTEQEIQEFVD 304

Query: 308 HLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPS 367
             ++KLR ++F R   YDEL+SGDP + T S+ GMG DGR  VTK  +RFLNTL T+G +
Sbjct: 305 DFILKLRTMKFARAAAYDELYSGDPTFITTSMAGMGNDGRHRVTKMDYRFLNTLDTIGNA 364

Query: 368 PEPNMTILWSEKLPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNNDDYAIACCVSPMIVG 427
           PEPN+T+LW  KLP +FK+++  +S   SS+QYE  + M  D   +   I+CCVSP+   
Sbjct: 365 PEPNLTVLWDSKLPYSFKRYSMSMSHKHSSIQYEGVETMAKDGYGEMSCISCCVSPLDPE 424

Query: 428 KQ-----MQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDH 482
            +     +Q+FGAR N+ K ML  +NGG D+  K       EP++ ++L+YD VME  D 
Sbjct: 425 NEEGRHNLQYFGARVNVLKAMLTGLNGGYDDVHKDYKVFDIEPVRDEILDYDTVMENFDK 484

Query: 483 FMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVAADSLSAIKY 542
            ++WL   Y+ A+NIIHYM DKY+YEA  MA     V   M  GI G +   DSLSAIKY
Sbjct: 485 SLNWLTDTYVDAMNIIHYMTDKYNYEAVQMAFLPTKVRANMGFGICGFANTVDSLSAIKY 544

Query: 543 AKVKPIRDEDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQ 602
           AKVK +RDE+G   D+E+EG++P++G +D R DD+A  +++ + +K+     Y++A  T 
Sbjct: 545 AKVKTLRDENGYIYDYEVEGDFPRYGEDDDRADDIAKLVMKMYHEKLASHKLYKNAEATV 604

Query: 603 SVLTITSNVVYGKKTGNTP---------DGRRAGAP---FGPGANPMHGRDQKGAVASLT 650
           S+LTITSNV Y K+TGN+P         DG    +    F PGANP + + + G + +L 
Sbjct: 605 SLLTITSNVAYSKQTGNSPVHKGVFLNEDGTVNKSKLEFFSPGANPSN-KAKGGWLQNLR 663

Query: 651 SVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEG----GQHL 706
           S+AKL F  A DGIS T  + P ALGK  + +  NL  ++DGYF   A I G    GQH+
Sbjct: 664 SLAKLEFKDANDGISLTTQVSPRALGKTRDEQVDNLVQILDGYFTPGALINGTEFAGQHV 723

Query: 707 NVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQSM 760
           N+NVM+ + + D +   E    + +R+SGY V    LT EQ+Q++  R F + +
Sbjct: 724 NLNVMDLKDVYDKIMRGE---DVIVRISGYCVNTKYLTPEQKQELTERVFHEVL 774


>UniRef50_Q2C4S5 Formate acetyltransferase n=7 Tax=Gammaproteobacteria
           RepID=Q2C4S5_9GAMM
          Length = 280

 Score =  408 bits (1048), Expect = e-112,   Method: Compositional matrix adjust.
 Identities = 187/270 (69%), Positives = 227/270 (84%)

Query: 11  AWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLWDKVMEGVKLENRTHA 70
           AW+GF+ G+WQ EVN RDFIQ NYTPYEGDESFLA  TE TT+LW+ V+EG+K E+RTHA
Sbjct: 11  AWKGFSAGNWQQEVNTRDFIQTNYTPYEGDESFLADVTETTTSLWNTVLEGIKEESRTHA 70

Query: 71  PVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIKMIEGSCKAYNREL 130
           PVDFDT + STITSHDAGYINK LEKIVGLQT+ PLKR++I  GGI+M++ SC+ Y R+L
Sbjct: 71  PVDFDTDLPSTITSHDAGYINKDLEKIVGLQTDKPLKRSIIANGGIRMVKSSCEVYGRKL 130

Query: 131 DPMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGI 190
           D  ++KIFT+YRKTHN+  FD+YT +IL CRKSG++TGLPDAYGRGRIIGDYRR++LYGI
Sbjct: 131 DESVEKIFTDYRKTHNKACFDLYTKEILACRKSGIITGLPDAYGRGRIIGDYRRLSLYGI 190

Query: 191 DYLMKDKLAQFTSLQADLENGVNLEQTIRLREEIAEQHRALGQMKEMAAKYGYDISGPAT 250
           D+L  DK  Q+ S QA LE G +LE+T+RLREE+A+Q +AL  +++M  KYG D+S PA 
Sbjct: 191 DFLKSDKQEQYKSTQAFLEQGHDLEKTLRLREELADQVQALEDIRQMGLKYGIDMSAPAR 250

Query: 251 NAQEAIQWTYFGYLAAVKSQNGAAMSFGRT 280
            AQEAIQ+TYFGYLAAVKSQNGAAMS GRT
Sbjct: 251 TAQEAIQFTYFGYLAAVKSQNGAAMSLGRT 280


>UniRef50_D1NCN8 Formate C-acetyltransferase n=1 Tax=Haemophilus influenzae HK1212
           RepID=D1NCN8_HAEIN
          Length = 218

 Score =  258 bits (658), Expect = 8e-67,   Method: Compositional matrix adjust.
 Identities = 119/131 (90%), Positives = 127/131 (96%)

Query: 599 IPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFA 658
           +PTQSVLTITSNVVYGKKTGNTPDGRR+GAPFGPGANPMHGRDQKGAVASLTSVAKLPFA
Sbjct: 1   MPTQSVLTITSNVVYGKKTGNTPDGRRSGAPFGPGANPMHGRDQKGAVASLTSVAKLPFA 60

Query: 659 YAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLD 718
           YAKDGISYTFSIVPNALG D E ++ NLAGLMDGYFHHEA++EGGQHLNVNV+NREMLLD
Sbjct: 61  YAKDGISYTFSIVPNALGNDAEAQRRNLAGLMDGYFHHEATVEGGQHLNVNVLNREMLLD 120

Query: 719 AMENPEKYPQL 729
           AMENP+KYPQL
Sbjct: 121 AMENPDKYPQL 131


>UniRef50_C6VIV4 Formate C-acetyltransferase n=25 Tax=Bacteria RepID=C6VIV4_LACPJ
          Length = 814

 Score =  199 bits (507), Expect = 3e-49,   Method: Compositional matrix adjust.
 Identities = 156/557 (28%), Positives = 257/557 (46%), Gaps = 62/557 (11%)

Query: 248 PATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVD 307
           PA +  EAIQ  +  +L      NG ++S+GR   +LD + E DLK G I    A E++ 
Sbjct: 267 PANSFYEAIQAVWLVHLTLQIESNGHSVSYGRLDQYLDPFYEHDLKTGAIDANGATELLT 326

Query: 308 HLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPS 367
           +L +K   +  +R+ ++ E  +G P++   +IGG   DG+  V   S+  L  +      
Sbjct: 327 NLCLKTLTINKVRSWQHTEFSAGSPLYQNITIGGQTPDGKDAVNPTSYLILRAI-AQAHL 385

Query: 368 PEPNMTILWSEKLPLNFKKFAAKVSIDTSSL-QYENDDLMRPDF--------NNDDYAIA 418
           P+PN+T+ +   L   F +   +V      +  + ND+++ P F        +  +Y+  
Sbjct: 386 PQPNLTVRYHHGLSDKFMRECVEVIKQGLGMPAFNNDEIIIPSFIRRGVKKEDAYNYSAI 445

Query: 419 CCVSPMIVGKQMQFFGARA------NLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLN 472
            CV   I GK    +G R       N  + +L  +NGG+D +   ++ P       D+ +
Sbjct: 446 GCVETAIPGK----WGYRCTGMSFINFPRVLLLIMNGGIDPESGKRLLPDYGKFT-DMTS 500

Query: 473 YDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVI---RTMACG--- 526
           +D++M   D  +  + +Q +   N      ++ +Y   L ++   D I   +T+  G   
Sbjct: 501 FDQLMTAWDKALREMTRQSVIIENSCDLALEQ-NYPDILCSVLTDDCIGRGKTIKEGGAV 559

Query: 527 ---IAGLSVA----ADSLSAIK---------------YAKVKPIRDEDGLAIDFEIEGEY 564
              I+GL V     ADSL+AIK               +A      DEDG  I   +  + 
Sbjct: 560 YDFISGLQVGIANLADSLAAIKKLVFEEKKLTTTQLWHALTTDFADEDGEKIRQMLINDA 619

Query: 565 PQFGNNDPRVDDLAVDLVERFMKKIQKLHTYR------DAIPTQSVLTITSNVVYGKKTG 618
           P++GN+D  VDDL V+  + ++ +I K    R        +      +I++NV  G  T 
Sbjct: 620 PKYGNDDDYVDDLIVEAYKPYIDEIAKYKNTRYGRGPIGGLRYAGTSSISANVGQGHSTL 679

Query: 619 NTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKD 678
            TPDGR A  P   G +P H  D  G  A   SV+KL       G+     + P  L  D
Sbjct: 680 ATPDGRHARTPLAEGCSPEHAMDTNGPTAVFKSVSKLSTKDITGGVLLNQKMSPQILRSD 739

Query: 679 DEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAV 738
           +   K  L  L+  +F+       G H+  N+++R+ L+DA  +P+K+  L +RV+GY+ 
Sbjct: 740 ESCMK--LVALLRTFFNRLH----GYHVQYNIVSRDTLIDAQNHPDKHRDLIVRVAGYSA 793

Query: 739 RFNSLTKEQQQDVITRT 755
            F  L+KE Q D+I RT
Sbjct: 794 FFVGLSKETQDDIIERT 810


>UniRef50_B2ISH7 Formate acetyltransferase, putative n=59 Tax=Bacteria
           RepID=B2ISH7_STRPS
          Length = 815

 Score =  191 bits (484), Expect = 1e-46,   Method: Compositional matrix adjust.
 Identities = 158/581 (27%), Positives = 263/581 (45%), Gaps = 69/581 (11%)

Query: 226 EQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLD 285
           ++ + L ++ ++ ++  Y+   PAT   EAIQ  +F         NG ++S+GR   ++ 
Sbjct: 249 KRKKELLEIADICSRVPYE---PATTFAEAIQSVWFIQCILQIESNGHSLSYGRFDQYMY 305

Query: 286 VYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLD 345
            Y++ DL++GK TE    E + +L +K   +  +R+  +    +G P++   +IGG   D
Sbjct: 306 PYMKADLESGKETEDSIVERLTNLWIKTITINKVRSQSHTFSSAGSPLYQNVTIGGQTRD 365

Query: 346 GRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKV-SIDTSSLQYENDD 404
            +  V   S+  L ++      P+PN+T+ +   L   F     +V  +      + ND+
Sbjct: 366 KKDAVNPLSYLVLKSV-AQTHLPQPNLTVRYHAGLDARFMNECIEVMKLGFGMPAFNNDE 424

Query: 405 LMRPDF--------NNDDYAIACCVSPMIVGKQMQFFGARA------NLAKTMLYAINGG 450
           ++ P F        +  DY+   CV   + GK    +G R       N  K +L  +N G
Sbjct: 425 IIIPSFIAKGVLEDDAYDYSAIGCVETAVPGK----WGYRCTGMSYMNFPKVLLITMNDG 480

Query: 451 VDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEAS 510
           +D     +  P     K D+ N+ E+    D  + +L +  +   N I    ++   +  
Sbjct: 481 IDPASGKRFAPSFGHFK-DMKNFSELENAWDKTLRYLTRMSVIVENSIDLSLEREVPDIL 539

Query: 511 LMALHD---------------RDVIRTMACGIAGLSVAADSLSAIKY-----AKVKPIR- 549
             AL D                D I  +  GIA LS   DSL+AIK       ++ P + 
Sbjct: 540 CSALTDDCIGRGKHLKEGGAVYDYISGLQVGIANLS---DSLAAIKKLVFEEERISPSQL 596

Query: 550 ---------DEDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYR---- 596
                     E+G  I   +  + P++GN+D   D L     + ++ +I K    R    
Sbjct: 597 WHALETDYAGEEGKVIQEMLIHDAPKYGNDDDYADKLVTAAYDIYVDEIAKYPNTRYGRG 656

Query: 597 --DAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAK 654
               I      +I++NV  G+ T  TPDGR AG P   G +P H  DQ G  + L SV+K
Sbjct: 657 PIGGIRYSGTSSISANVGQGRGTLATPDGRNAGTPLAEGCSPSHNMDQHGPTSVLKSVSK 716

Query: 655 LPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNRE 714
           LP      G+     + P  L K+++  K  L  L+  +F+       G H+  NV++RE
Sbjct: 717 LPTDEIVGGVLLNQKVNPQTLAKEED--KLKLIALLRTFFNRLH----GYHIQYNVVSRE 770

Query: 715 MLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRT 755
            L+DA ++PEK+  L +RV+GY+  FN L+K  Q D+I RT
Sbjct: 771 TLIDAQKHPEKHRDLIVRVAGYSAFFNVLSKATQDDIIGRT 811


>UniRef50_P75793 Putative formate acetyltransferase 3 n=109 Tax=Bacteria
           RepID=PFLF_ECOLI
          Length = 810

 Score =  180 bits (457), Expect = 2e-43,   Method: Compositional matrix adjust.
 Identities = 155/563 (27%), Positives = 261/563 (46%), Gaps = 68/563 (12%)

Query: 248 PATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQE-AQEMV 306
           P     +A+Q  YF  L      NG ++SFGR   +L  Y  RD++  +  ++E A EM+
Sbjct: 257 PPQTFWQALQLCYFIQLILQIESNGHSVSFGRMDQYLYPYYRRDVELNQTLDREHAIEML 316

Query: 307 DHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGL-DGRTLVTKNSFRFLNTLYTMG 365
               +KL  V  +R+  + +  +G P++   +IGG  L DG+ +   N   +   L + G
Sbjct: 317 HSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQNLVDGQPMDAVNPLSYA-ILESCG 375

Query: 366 P--SPEPNMTILWSEKLPLNFKKFAAKV-SIDTSSLQYENDDLMRPDF--------NNDD 414
              S +PN+++ +   +  +F     +V         + ND+++ P+F        +  D
Sbjct: 376 RLRSTQPNLSVRYHAGMSNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLGIEPQDAYD 435

Query: 415 YAIACCVSPMIVGKQMQFFGARA------NLAKTMLYAINGGVDEKLKMQVGPKSEPIK- 467
           YA   C+   + GK    +G R       N A+ ML A+ GG D        P+ + +  
Sbjct: 436 YAAIGCIETAVGGK----WGYRCTGMSFINFARVMLAALEGGHDATSGKVFLPQEKALSA 491

Query: 468 GDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACG- 526
           G+  N+DEVM+  D  + +  ++ I    ++  M ++  ++    AL D  + R  +   
Sbjct: 492 GNFNNFDEVMDAWDTQIRYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAKSIKQ 551

Query: 527 -------IAGLSVAADSLSAIKYAKVKPIRDEDG----------LAIDFE---------- 559
                  ++GL V   +L     A VK +  E G          LA DF+          
Sbjct: 552 GGAKYDWVSGLQVGIANLGN-SLAAVKKLVFEQGAIGQQQLAAALADDFDGLTHEQLRQR 610

Query: 560 -IEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAI-PT-----QSVLTITSNVV 612
            I G  P++GN+D  VD L     + ++ ++++ H  R    P          +I++NV 
Sbjct: 611 LINGA-PKYGNDDDTVDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISANVP 669

Query: 613 YGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVP 672
           +G +T  TPDGR+A  P   GA+P  G D  G  A + SV KLP A    G+     + P
Sbjct: 670 FGAQTMATPDGRKAHTPLAEGASPASGTDHLGPTAVIGSVGKLPTAAILGGVLLNQKLNP 729

Query: 673 NALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIR 732
             L  ++E  K  L  L+  +F     +  G H+  N+++RE LLDA ++P++Y  L +R
Sbjct: 730 ATL--ENESDKQKLMILLRTFF----EVHKGWHIQYNIVSRETLLDAKKHPDQYRDLVVR 783

Query: 733 VSGYAVRFNSLTKEQQQDVITRT 755
           V+GY+  F +L+ + Q D+I RT
Sbjct: 784 VAGYSAFFTALSPDAQDDIIART 806


>UniRef50_A0Q2M5 Pyruvate formate-lyase n=9 Tax=Bacteria RepID=A0Q2M5_CLONN
          Length = 803

 Score =  179 bits (455), Expect = 3e-43,   Method: Compositional matrix adjust.
 Identities = 156/559 (27%), Positives = 259/559 (46%), Gaps = 68/559 (12%)

Query: 248 PATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVD 307
           PAT   EA Q  +F         NG A+S  R   ++  Y + D+    +T++E +E++ 
Sbjct: 258 PATTFYEACQSFWFVQAIISLESNGHAISPARFDQYMYPYFKSDVDNNVVTKEENREILQ 317

Query: 308 HLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPS 367
            L +K   +  +R     + FSG  ++    +GG   +G+    + S+  L+   ++   
Sbjct: 318 CLWVKFNDLTKVRDETTTKAFSGYSMFQNLIVGGQTEEGKDATNELSYMCLDATGSL-KL 376

Query: 368 PEPNMTI-LWSEKLPLNFKKFAAKVS-IDTSSLQYENDDLMRPDFNND--------DYAI 417
           P+P++++ +WS K P  F     +++ + T    + ND+++ P   N+        DYAI
Sbjct: 377 PQPSLSVRIWS-KTPEEFLIRTCELTRLGTGLPAFYNDEVIIPMLVNNGMTLEDARDYAI 435

Query: 418 ACCVSPMIVGKQMQFF-GARANLAKTMLYAI-NGGVDEKLKMQVGPKSEPIKGDVLNYDE 475
             CV P   GK   ++  A  NLA+ +   I NG +D K   QVGPK+   + +  + DE
Sbjct: 436 VGCVEPQKPGKTDGWYDAAFFNLAQILKLTIDNGKMDGK---QVGPKTGEFE-EFKDIDE 491

Query: 476 VMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMA----------C 525
           V+E     M++   Q ++A N +   H + +    L A+ D  + +  +           
Sbjct: 492 VIEAYKKQMEYFVAQMVSADNCVDIAHRERAPLPFLSAMLDDCIAKGKSIQEGGGHYRFS 551

Query: 526 GIAGLSVA--ADSLSAIKYAKVKPIRDEDGLAID--------------------FEIEG- 562
           G  G+ +A   DS  AIK    K + D++ + +D                     E++G 
Sbjct: 552 GPLGVGIANVGDSFMAIK----KLVFDDEKITLDKLKQALDGNFGKDEKDEGKKNELQGI 607

Query: 563 ------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKK 616
                   P+FGN+   VD+   +    +  ++ K    R       +  +++NV  G  
Sbjct: 608 KQMLLHRAPKFGNDIDEVDEFTREGALIYCNEVLKHFNQRGGKFLPGLYPVSNNVHLGSL 667

Query: 617 TGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALG 676
            G TPDGR A  P   G +P  G D  G  A+  SVAKL    A  G  +     P++L 
Sbjct: 668 VGATPDGREAYQPIADGVSPTRGADVNGPTAAANSVAKLEHYAAPSGTLFNQKFNPSSLK 727

Query: 677 KDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGY 736
            D+ +R  NL  L+  YF H+     G H+  NV+++ +LLDA ++PEKY  L +RV+GY
Sbjct: 728 GDNGLR--NLGTLIRSYFDHK-----GMHIQFNVVDKNVLLDAQKHPEKYRDLIVRVAGY 780

Query: 737 AVRFNSLTKEQQQDVITRT 755
           + +F  L KE Q D+I RT
Sbjct: 781 SAQFICLNKEIQDDIIKRT 799


>UniRef50_B1C5P6 Putative uncharacterized protein n=3 Tax=Bacteria
           RepID=B1C5P6_9FIRM
          Length = 824

 Score =  173 bits (439), Expect = 2e-41,   Method: Compositional matrix adjust.
 Identities = 181/704 (25%), Positives = 309/704 (43%), Gaps = 94/704 (13%)

Query: 127 NRELDPMIKKIFTEYR-KTHNQGVFDVYTPDILRCRKSGVLTGLPDAY-GRGRIIGDYRR 184
           N E   ++++I   ++ KT    V    T ++L  +K GVL    +   G G II ++ +
Sbjct: 134 NEENKKIMREILPLWKGKTLKDRVLKTQTKEVLEDKKVGVLGWEGNVTAGEGHIIMNFEK 193

Query: 185 V---ALYGIDYLMKDKLAQFTSLQAD---------------------LENGVNLEQTIRL 220
           V      GI    +DKL++      D                     +E  ++L +   +
Sbjct: 194 VLKVGFRGIVNEAEDKLSKLDYTDPDDLRKVSFYKAVKIVYSASSEFVERYIDLLEGKII 253

Query: 221 REEIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRT 280
            E+  ++ + L Q+K+      Y+   P T  + A+Q  +F  L +    NG +MS GR 
Sbjct: 254 IEKDEQRKKELKQIKKNCENIEYN---PPTTFKSAVQLLWFVQLISQIEANGHSMSMGRV 310

Query: 281 STFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIG 340
             ++  + +RD+  G +   EA+E ++   +KL  V  +R   +    +G P +    IG
Sbjct: 311 DKYIYPFYKRDIDKGILNRDEAKEYIECFYLKLFTVIKIRPWSHTRFVAGYPTYQNIIIG 370

Query: 341 GMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKV-SIDTSSLQ 399
           G  +DG++ + + S+  L  L  +  S EPN  I   E +P +F     KV  +      
Sbjct: 371 GKNIDGKSDLNEMSYILLEALGDIKLS-EPNFYIRCHEDMPKDFVDLMIKVIKMGFGMPA 429

Query: 400 YENDDLM------RPDFNND--DYAIACCVSPMIVGKQMQFFGARA------NLAKTMLY 445
             NDD++      R     D  DY+   C+   + GK    +G RA      N+ K M  
Sbjct: 430 LVNDDVIINSLIDRGVSKEDAYDYSTMGCLEVQVPGK----WGYRANGKTKVNVLKIMEI 485

Query: 446 AINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKY 505
           A+NGGVD K  ++   +  P      ++DEV +     M +  +  +TA NI     ++ 
Sbjct: 486 ALNGGVDPKSGIKT-IEGIPEFTKFTDFDEVYKAYCKAMIYYMRLQVTADNINDIAMEEL 544

Query: 506 SYEASLMALHDRDVIR------------TMACGIAGLSVAADSLSAIKYA----KVKPIR 549
             +A    L +  + R             ++  + G     +SL A+K A    K+  + 
Sbjct: 545 VPDAFCSGLVEDCIGRGKTIKEGGAVYDMISGALVGGPNVGNSLYALKKAVFEDKLLTLE 604

Query: 550 D-EDGLAIDFE-IEGE---------YPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYR-- 596
           D ++ +  ++E IEGE           ++GN++   DD+ V + + ++  I      R  
Sbjct: 605 DVQNAVRSNYEGIEGEKIRLLLQNKIDKYGNDNDEADDMVVKIYKPYIDNIASYKNTRFG 664

Query: 597 ----DAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSV 652
                 +   S +TI+SNV  G K G TPDGR+   P   G +PMHG ++ G  + + SV
Sbjct: 665 RGPIGGMFIPSTVTISSNVPDGAKVGATPDGRKDEEPTAEGVSPMHGTEKNGPTSVINSV 724

Query: 653 AKLPFAYAKDGISYTFSIVPNAL--GKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNV 710
           +KL       G        P  +   KD+E        L++ +F      + G H+  N+
Sbjct: 725 SKLETRKMTGGQLLNMRFNPTTVKTKKDEE----KFYALIEAFFK-----KNGWHVQFNM 775

Query: 711 MNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITR 754
           ++ + L+ A + PEKY  L +RV+GY+  F SL K  Q D+I+R
Sbjct: 776 ISTDTLIKAQKEPEKYQDLVVRVAGYSALFTSLDKITQDDIISR 819


>UniRef50_D1ARQ1 Pyruvate formate-lyase n=3 Tax=Bacteria RepID=D1ARQ1_SEBTE
          Length = 807

 Score =  169 bits (429), Expect = 3e-40,   Method: Compositional matrix adjust.
 Identities = 155/579 (26%), Positives = 263/579 (45%), Gaps = 75/579 (12%)

Query: 233 QMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDL 292
           ++K+++  + + + G A +  EA++  Y  +L  +   NG + SFGR   ++  Y + D+
Sbjct: 243 ELKDLSKMFAHLMEGKAESFHEAVEAVYLTHLLMMIESNGHSFSFGRFDQYIYPYYKADI 302

Query: 293 KAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTK 352
            +GKI++++A E++ H  +    +  +R   + +   G P+++   +GGM  DG      
Sbjct: 303 DSGKISKEKALEIITHFFLMTNSLNKVRPWGHTQYSGGYPLYSNLIVGGMKPDGSEGTND 362

Query: 353 NSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKV---SIDTSSLQYEN---DDLM 406
            S+  L  +  +   PEPN+++ + E+ P +  K +A++        SL  +      +M
Sbjct: 363 ISYLCLEAM-NLSRLPEPNLSVRFCEETPRSLLKDSARLIRKGFGMPSLFCDEVVIPAMM 421

Query: 407 RPDFNND---DYAIACCVSPMIVGKQMQFFGARA------NLAKTMLYAINGGVDEKLKM 457
             D + +   DYA   CV   I GK    +G RA      N  K +   +N G+D    +
Sbjct: 422 TLDLDIETARDYASMGCVETAIPGK----WGHRATGMTYINFGKILELIMNNGMDPASGI 477

Query: 458 QV----GPKSEPIKGDVLNYDEVMERMDHFMDWLAK-----QYITALNIIHYMHDKYSYE 508
           Q+    G     I  D  +YDE+ +  +  + + +        +   ++ H+  D ++  
Sbjct: 478 QLFSITGKNDRNI--DFKSYDELWKAWETALKFYSDLAVDCDLVCDRSLKHFDADAFA-S 534

Query: 509 ASLMALHDRDVIRTMACGIA----------GLSVAADSLSAI-------KYAKVKPIRDE 551
           A++    +R   +T+  G A          G SV  DSL+A+       K   +K +R  
Sbjct: 535 ATINCSLERG--KTLKNGGAEYDYVSQSNIGPSVVGDSLAAVKKLVFDDKVITMKQLR-- 590

Query: 552 DGLAIDFE-IEG--------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIP-- 600
           D +  +FE IEG        + P+FGN+   VD++  D+ E ++  +   HT R      
Sbjct: 591 DAMDTNFEGIEGAKIRKLCRQAPKFGNDIDYVDNIVADVYESYLALLPNYHTDRYGCGPK 650

Query: 601 ----TQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLP 656
               T S   ITS V  G   G TPDGR AG P   GA+P  G D++G  A + SV+KLP
Sbjct: 651 GCGYTMSTSNITSYVPNGFDVGATPDGRFAGKPLNEGASPCLGADKEGPTAVINSVSKLP 710

Query: 657 FAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREML 716
                 G        P AL  ++ + K          F   A  +   H   N+++   L
Sbjct: 711 NKKIAGGQLLNMRFAPGALAGEENLEKF-------VSFIEAARYKNIFHNQFNIVDGATL 763

Query: 717 LDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRT 755
             A ENPE++  L +RV+GY   F++L  E Q  +I RT
Sbjct: 764 KAAKENPEEHADLMVRVAGYCALFSTLMPEAQDAIIERT 802


>UniRef50_A6LQ73 Pyruvate formate-lyase n=6 Tax=Bacteria RepID=A6LQ73_CLOB8
          Length = 784

 Score =  162 bits (411), Expect = 3e-38,   Method: Compositional matrix adjust.
 Identities = 146/547 (26%), Positives = 241/547 (44%), Gaps = 51/547 (9%)

Query: 248 PATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVD 307
           PA    EA+Q  +F ++      N ++ S GR   FL  Y +RD+  G I +++A E+++
Sbjct: 245 PAQTFHEAVQAIWFLFVILHMESNASSFSPGRMDEFLYPYYKRDIHLGNIDDKKALEIIE 304

Query: 308 HLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPS 367
            L +K   + +LR     + F+G PI    +IGG          + SF FL     +G  
Sbjct: 305 CLWLKFNEIVYLRNSHSAKFFAGFPIGFNIAIGGQDEKSNDFSNELSFLFLKAQEHLG-L 363

Query: 368 PEPNMTILWSEKLPLNFKKFAAKVSIDTSSL-QYENDDLMRPDF--------NNDDYAIA 418
           P+PN+++   +       K + KV    S + Q+ ND+ + P          +  DYAI 
Sbjct: 364 PQPNLSVRLHKNTSEKLLKESIKVVAKGSGMPQFFNDESVVPSMIDLGIKEKDARDYAIV 423

Query: 419 CCVSPMIVGKQMQFF-GARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVM 477
            CV     G  + +   A  NL K +   +NGG   K  +     S+ + G++  Y++  
Sbjct: 424 GCVELTTQGNNLGWSDAAMFNLNKVLEITLNGG---KCLISGDSLSQDL-GNLTTYEKYE 479

Query: 478 ERMDHF---MDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTM----------A 524
           +  + F   +D+   + I A   +   H        L ++ D  + + +           
Sbjct: 480 DLEEAFAKQIDYFIDRMILACEQVEKAHIDVLPSPFLSSVIDDCIEKGVDVTAGGAVYNL 539

Query: 525 CGIAGLSVA--ADSLSAIK---YAKVKPIRDEDGLAIDFEIEG----------EYPQFGN 569
            GI  + VA  ADSL+AIK   Y + +  ++E   A+    EG            P++GN
Sbjct: 540 SGIQMIQVANLADSLAAIKLLVYDEKRISKEELLKALQNNFEGYEVIRAMLLNRAPKYGN 599

Query: 570 NDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAP 629
           +   VD++       F  K++    YR       + T++++V  G+  G + DGR A AP
Sbjct: 600 DIQWVDEIGAKWARYFNGKLKSYTNYRGGKYHTGMYTVSAHVPMGENVGASADGRYAKAP 659

Query: 630 FGPGA-NPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAG 688
              G  +P++GRD  G  A L SV+KL      +G       +P       E+ +   A 
Sbjct: 660 LADGGMSPVYGRDIAGPTAVLKSVSKLDNVLTTNGGLLNMKFLPEFF--KHEIGRDKFAR 717

Query: 689 LMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQ 748
            +  +   E       H+  NV+ +E LL A ++PE Y  LT+RV+GY   F  L  E Q
Sbjct: 718 FLRTFVDLEIP-----HIQFNVLRKEDLLAAQKDPENYRSLTVRVAGYTAYFTELAGELQ 772

Query: 749 QDVITRT 755
            ++I RT
Sbjct: 773 NEIIART 779


>UniRef50_O94132 Formate C-acetyltransferase (Fragment) n=2 Tax=Piromyces sp. E2
           RepID=O94132_9FUNG
          Length = 154

 Score =  162 bits (409), Expect = 5e-38,   Method: Compositional matrix adjust.
 Identities = 74/152 (48%), Positives = 111/152 (73%), Gaps = 2/152 (1%)

Query: 24  VNVRDFIQKNYTPYEGDESFLA-GATEATTTLWDKVMEGVKLENRTHAPVDFDTAVASTI 82
           ++V  +I++N+TPYEGD SFL   A+  T  +W+K  E    E +T+  +D D    ST+
Sbjct: 4   IDVAKWIKENHTPYEGDASFLVTDASAKTKDVWNKCCELRAEEIKTNGCLDVDNKTISTV 63

Query: 83  TSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIKMIEGSCKAYNRELDPMIKKIFTEYR 142
            SH+AGYI K+ E IVGLQT+APLKR++ PFGG+++++ + KAY+R +DP ++++F +YR
Sbjct: 64  NSHEAGYIIKEKEDIVGLQTDAPLKRSIKPFGGVRIVKNALKAYDRTIDPSVEEVF-KYR 122

Query: 143 KTHNQGVFDVYTPDILRCRKSGVLTGLPDAYG 174
           KTHN  VFD+YTP++ + R + +LTGLPD YG
Sbjct: 123 KTHNDCVFDIYTPEMRKARSNAILTGLPDGYG 154


>UniRef50_A6TKL5 Pyruvate formate-lyase n=1 Tax=Alkaliphilus metalliredigens QYMF
           RepID=A6TKL5_ALKMQ
          Length = 806

 Score =  161 bits (408), Expect = 7e-38,   Method: Compositional matrix adjust.
 Identities = 157/574 (27%), Positives = 266/574 (46%), Gaps = 50/574 (8%)

Query: 223 EIAEQHRALGQMKEM---AAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGR 279
           E+A+Q +   + KE+   A    +    PA +  +AIQ   F  L      NG ++  GR
Sbjct: 237 ELADQEKNPVRKKELEKIADVCQWVPENPARDTWDAIQVVAFMQLIIQTETNGDSVCPGR 296

Query: 280 TSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESI 339
              +L  Y + D+  G+ T  E QE++D L +KL  +  ++  E   +  G P+  T +I
Sbjct: 297 LDQYLYSYYKNDMAEGRYTIDEIQELLDCLWIKLNEIIKIQASESVRIHPGFPMTPTVTI 356

Query: 340 GGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFK-KFAAKVSIDTSSL 398
           GG   +G     + S+  LN+   +  +  P  T+ + +  P +FK +    V + T   
Sbjct: 357 GGQTPEGEDATNELSYLMLNSQEHIRLT-NPQFTVRFHKDTPEDFKLRVVEVVKLGTGMP 415

Query: 399 QYENDD-----LMR--PDFNND---DYAIACCVSPMIVGKQMQFFGARANLAKTMLYAIN 448
               D+     L R  PD   +   DY I  CV     G Q +  G   N+A+ +  A+N
Sbjct: 416 AMFGDEACIAALKRGCPDMPMERIRDYRIVGCVELAPRGFQGRVNGGFLNVARVVDLALN 475

Query: 449 GGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAK-QYITA--LNIIHYMHDKY 505
            GVD     Q+GP++   + D+ ++D+V+  +     +  K Q I A  ++++   H  +
Sbjct: 476 NGVDRLTNEQIGPQTGAPE-DLKDFDDVLTAVRTQTAYFVKHQVINAAVVDMVQREHTPH 534

Query: 506 SYEASLMA---LHDRDVIR--TMACGI----AGLSVAADSLSAIKYA----------KVK 546
            + +SL+     + +D+ +  ++  G      G + AADSL  +K A          ++K
Sbjct: 535 LFLSSLVEGCIENGKDMTQGGSLWGGTPILHVGEATAADSLIGVKKAVFDDQLISMKELK 594

Query: 547 PIRDED-----GLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPT 601
            I D +     G  I ++     P++GN+D   D++   ++  F  +I+K         T
Sbjct: 595 EILDSNFAGAQGEKI-YQALLAMPKYGNDDDYADEVMQKMINIFFDEIEKHKDIDGRFYT 653

Query: 602 QSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAK 661
            ++LT+ + V +G  TG T +GR+A  P     +  +G D++G  A L S +K+      
Sbjct: 654 STILTLGATVPHGWTTGATANGRKATMPVADSMSASNGADKEGPTAMLLSASKIDQTRTI 713

Query: 662 DGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAME 721
           +G          AL +   +++  L  L+  YF        GQ + VNV++   L DA E
Sbjct: 714 EGNVVNLKFTKMALEEKKNLQQ--LVNLVSVYFDDLK----GQEIQVNVVDESTLKDAQE 767

Query: 722 NPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRT 755
            PEK+  L IRV+GY+ RF  L KE Q D+I RT
Sbjct: 768 YPEKHQDLIIRVAGYSARFTELAKELQDDIIRRT 801


>UniRef50_B8FA81 Formate C-acetyltransferase n=1 Tax=Desulfatibacillum alkenivorans
           AK-01 RepID=B8FA81_DESAA
          Length = 831

 Score =  160 bits (406), Expect = 1e-37,   Method: Compositional matrix adjust.
 Identities = 149/583 (25%), Positives = 259/583 (44%), Gaps = 54/583 (9%)

Query: 215 EQTIRLREEIAEQHRALGQMKEM---AAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQN 271
           E+  +  EE A +     + +E+   A +  +    P     EA+Q  +   L  + S  
Sbjct: 256 ERLAKKAEEAASEENDPDRQRELLAAAKRCRHSPWNPPRTFHEAVQAMWLILLGGLVSHG 315

Query: 272 GAA-MSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKL----RMVRFLRTPEYDE 326
               ++ GR   +L  Y ++D+++G+I +  A  +++ L++KL     ++ ++     +E
Sbjct: 316 MVGILAVGRLDQYLYPYYKKDVESGRIDQAMAVRLMEELLIKLGANLMILPYVGKNTGNE 375

Query: 327 LFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKK 386
           L S   +    +IGG+   G+  V   ++  L     +  S   + T+  S++ P  F +
Sbjct: 376 LGSDSCV---PTIGGVDAQGKDAVNPLTYAVLEAFANV-KSLGNSFTVRLSQESPPEFWQ 431

Query: 387 FAAKVSIDTSSLQYENDDLMRPDFNN--------DDYAIACCVSPMIVGKQMQFF-GARA 437
            A +   +TS     ND+++ P   N         DY +  CV P   G       G   
Sbjct: 432 KALETYRETSGAALFNDEIVTPALQNCGMTLEDARDYGVIGCVEPTGDGDAFGCTSGNDV 491

Query: 438 NLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNI 497
           +L+  +  A+  G    +   +GPK+   K     +D+V+E     ++++      A+N+
Sbjct: 492 SLSAALEMALGDGYLRVMGKAIGPKTGNPK-KFKTFDQVLEAFKKQVEFMVDTVARAVNL 550

Query: 498 IH--YMHDKYSYEASLMALHDRDVIRTMACGIA----------GLSVAADSLSAIK---- 541
               YM + ++   S       D  R M  G A          G+  AADSL+AIK    
Sbjct: 551 KDQIYMEEYHNPYISCTLTGCLDNARDMTQGGAKYNFGSISGRGMGTAADSLAAIKCFVF 610

Query: 542 ------YAKVKPIRDEDGLAIDFE---IEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKL 592
                  AK+  + D +    D E   +    P FG++DP  DD+A ++   F K +   
Sbjct: 611 DQKTFSMAKILKMLDCNFKGYDKERAMLAHRAPAFGSDDPYADDIAKEVCAFFCKTVASK 670

Query: 593 HTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSV 652
            T R      S  +   +V+ G   G TP+GR AG P     +P +G +++G    L SV
Sbjct: 671 QTLRGGPFRPSFFSYGVHVLEGLYIGATPNGRLAGTPVSNSLSPTNGSEKQGPTGVLGSV 730

Query: 653 AKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMN 712
           AKL  +   +G S    ++P+    ++ + K  + GL+ G+F       GG  +  NV++
Sbjct: 731 AKLDHSLISNGSSVNIKLMPSMFQGEERLNK--MIGLVKGFF-----ASGGMEVQPNVVS 783

Query: 713 REMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRT 755
            + LLDA ++PE Y  L +RVSGY+  F  L K  Q ++I RT
Sbjct: 784 NQTLLDAQKHPENYRDLVVRVSGYSAFFTDLGKPIQDEIIQRT 826


>UniRef50_B6FX97 Putative uncharacterized protein n=4 Tax=Firmicutes
           RepID=B6FX97_9CLOT
          Length = 796

 Score =  160 bits (404), Expect = 3e-37,   Method: Compositional matrix adjust.
 Identities = 144/544 (26%), Positives = 244/544 (44%), Gaps = 45/544 (8%)

Query: 248 PATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVD 307
           P     EA+Q  +F +       N ++ S GR   +L  Y + D++ G I+EQ+A E+++
Sbjct: 257 PPKTFHEAVQSLWFLFTILHMESNASSFSPGRMDQYLYPYYKEDIEKGIISEQDALEIIE 316

Query: 308 HLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPS 367
            L +K   + +LR     + F+G PI    +IGG+  +G  +    S   L   Y +G  
Sbjct: 317 CLWLKFNQIVYLRNQHSAKYFAGFPIGFNIAIGGVDENGDDIYNNLSLLILRAQYHLG-L 375

Query: 368 PEPNMTILWSEKLPLNFKKFAAKVSIDTSSL-QYEND--------DLMRPDFNNDDYAIA 418
           P+PN+++  ++       + + KV    S + Q+ ND        DL   + +  +YA+ 
Sbjct: 376 PQPNLSVRLNKNTSHELMQESIKVVAKGSGMPQFFNDESIIKAMIDLGIEEKDARNYAVV 435

Query: 419 CCVSPMIVGKQMQFF-GARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVM 477
            CV     G  + +   A  NL K +   +N G       Q+G     ++ D   ++++ 
Sbjct: 436 GCVELTTHGNNLGWSDAAMFNLNKALELTLNEGKCLLTGEQIGLNLGKLE-DYKTFEDLE 494

Query: 478 ERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDR------DVIRTMA----CGI 527
           E     +D+   + + A  ++   H      A L  + D       DV R  A     GI
Sbjct: 495 ESFRKQIDYFINEMMKAEVVVEKAHQDCLPSAFLSTVIDDCLEKGLDVTRGGAKYNLSGI 554

Query: 528 AGLSVA--ADSLSAIK---YAKVKPIRDE--DGLAIDFE--------IEGEYPQFGNNDP 572
             + VA  ADSL+AIK   Y +    ++E    L  DF+        +  + P++GN+  
Sbjct: 555 QMIQVANLADSLAAIKELVYDEEMISKEELLQALRDDFKGHEITQTMLLNKAPKYGNDVK 614

Query: 573 RVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGP 632
            VDDL       F ++++    YR       + T++++V  G+  G +PDGR A  P   
Sbjct: 615 WVDDLGTKWAGYFRERMKDYTNYRGGAYHTGMYTVSAHVPMGENVGASPDGRNALTPLAD 674

Query: 633 GA-NPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMD 691
           G  +P++GRD  G  A + SV+++   Y  +G       +P     +  + K      + 
Sbjct: 675 GGMSPVYGRDIAGPTAVIKSVSRISNDYTTNGGLLNMKFLPEFFKTETGMLK--FESFLR 732

Query: 692 GYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDV 751
            +   E       H+  NV+ RE LLDA  +PE++  LTIRV+GY   F  L  + Q ++
Sbjct: 733 AFVDLEVP-----HIQFNVVRREDLLDAKVHPERHKSLTIRVAGYTAYFVELAGKLQDEI 787

Query: 752 ITRT 755
           I RT
Sbjct: 788 IERT 791


>UniRef50_A8GF53 Pyruvate formate-lyase n=31 Tax=Bacteria RepID=A8GF53_SERP5
          Length = 810

 Score =  159 bits (401), Expect = 5e-37,   Method: Compositional matrix adjust.
 Identities = 142/561 (25%), Positives = 256/561 (45%), Gaps = 64/561 (11%)

Query: 248 PATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQE-AQEMV 306
           P     +A+Q  YF  L      NG ++SFGR   +L  +  RD++  +   +E A EM+
Sbjct: 257 PPQTFWQALQLCYFIQLTLQIESNGHSVSFGRLDQYLYPWYRRDVELEQTLPRERAIEML 316

Query: 307 DHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGL-DG--RTLVTKNSFRFLNTLYT 363
               +KL  +  +R+  + +  +G P++   +IGG  L DG  R  V   S+  L +   
Sbjct: 317 HSCWLKLLEINKIRSGSHSKASAGSPLYQNVTIGGQQLVDGSPRDAVNPLSYTILESCGR 376

Query: 364 MGPSPEPNMTILWSEKLPLNFKKFAAKV-SIDTSSLQYENDDLMRPDF--------NNDD 414
           +  S +PN+++ +   +  +F     +V         + ND+++ P+F        +  D
Sbjct: 377 L-RSTQPNLSVRYHAGMSSDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLGVEPQDAYD 435

Query: 415 YAIACCVSPMIVGKQMQFFGARA------NLAKTMLYAINGGVDEKLKMQVGPKSEPI-K 467
           YA   C+   + GK    +G R       N A+ +L A+  G D        P+   + +
Sbjct: 436 YAAIGCIETAVGGK----WGYRCTGMSFINFARVLLAALEQGRDATSGKVFLPQELALSR 491

Query: 468 GDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHD----------- 516
           G+  ++D+V+   D  + +  ++ I    ++  + ++ +++    AL D           
Sbjct: 492 GNFSHFDQVLGAWDSQIRYYTRKSIEIECVVDSVLEENAHDILCSALVDDCIERGKSIKQ 551

Query: 517 ----RDVIRTMACGIAGL--SVAADSLSAIKYAKVKPIRDEDGLAIDFE-IEGEY----- 564
                D +  +  GIA L  S+AA      +   +   +    LA DF+ + GE      
Sbjct: 552 GGAKYDWVSGLQVGIANLGNSLAAVRKLVFEQGAIGQQQLAAALANDFDGLSGEQLRQRL 611

Query: 565 ----PQFGNNDPRVDDLAVDLVERFMKKIQKLHTYR------DAIPTQSVLTITSNVVYG 614
               P++GN+   VD L V   + ++ ++ + H  R               +I++NV +G
Sbjct: 612 LNAAPKYGNDVDEVDQLLVRAYQSYIDELAQYHNTRFGRGPIGGTYYAGTSSISANVPFG 671

Query: 615 KKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNA 674
             T  TPDGR+A  P   GA+P  G D  G  A   S++KLP A    G+     + P  
Sbjct: 672 AATLATPDGRKAHTPLAEGASPASGTDHLGPTAVFNSLSKLPTAAILGGVLLNQKLNPAT 731

Query: 675 LGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVS 734
           L  ++ V +  L  ++  +F  E  +  G H+  N+++RE LL+A ++P++Y  L +RV+
Sbjct: 732 L--ENPVDREKLMLMLRTFF--ETYL--GWHVQYNIVSRETLLEAKQHPDQYRDLVVRVA 785

Query: 735 GYAVRFNSLTKEQQQDVITRT 755
           GY+  F +L+ + Q D+I RT
Sbjct: 786 GYSAFFTALSPDAQDDIIART 806


>UniRef50_B6FJR9 Putative uncharacterized protein n=1 Tax=Clostridium nexile DSM
           1787 RepID=B6FJR9_9CLOT
          Length = 794

 Score =  158 bits (399), Expect = 1e-36,   Method: Compositional matrix adjust.
 Identities = 145/556 (26%), Positives = 251/556 (45%), Gaps = 71/556 (12%)

Query: 248 PATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVD 307
           PA   QEAIQ  YF +++    QN AA + GR   +   Y + D+++G+ITE E QE+++
Sbjct: 253 PARTFQEAIQSFYFYHISIFMEQNAAAYNPGRMDQYFYPYYKVDIESGRITEDEGQELLE 312

Query: 308 HLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNT-----LY 362
            L +K       +        +G P++ T   GG+  +GR  V   S+  L       LY
Sbjct: 313 CLWVKFSEPCVFQDATTARYSAGYPMFQTLCCGGIDAEGRDAVNDISYMMLQATQDVLLY 372

Query: 363 TMGPSPEPNMTILWS-EKLPLNF-KKFAAKVSIDTSSLQYENDDL-MRPDFNND------ 413
                 +PNM + +S  K P  F KK A  +S+ T    + NDD+ +R   N        
Sbjct: 373 ------QPNMCVRYSMAKNPTKFLKKVAEVISLGTGFPAFYNDDVGIRMLMNKGIPLKEA 426

Query: 414 -DYAIACCVSPMIVGKQMQFFG-ARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVL 471
            D+  A CV   + G+   +   A  NL   + +A+  GV+ K   +V  ++    GD  
Sbjct: 427 YDWNPAGCVETNLDGRLRHYSAFADINLGGIIEFALTNGVNRKTGRKVATET----GDPT 482

Query: 472 NYDEVMERMDHFMDWLAKQYITALNII----HYMHD-KYSYEASLMALHDRDVIRT---- 522
            +    E  + F + + +Q   ++ I     H + D         ++L  R+ ++     
Sbjct: 483 TF----ETYEDFENAVKEQLKYSVRICVKGSHIIDDICMDRIVPALSLSFRECVKNAKDY 538

Query: 523 -------------MACGIAGLSVAADSLSAIKYAKVKPIRDEDGL-AIDFEIEG------ 562
                        +  G+A L  + +++  + Y + K +  ED + A+D + EG      
Sbjct: 539 AWGGAKYNTGNGIILIGVADLINSMEAIRDLVYDR-KLVSMEDMVKALDADFEGYEEIQK 597

Query: 563 ---EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGN 619
              E  ++GN+D  V+D+   ++     +I+K H+    + T  +L ++ N  +G+  G 
Sbjct: 598 LCKESHKYGNDDDDVNDITSHMLTFIADEIEKYHSKFGQM-TPGILPVSGNTPFGQDVGA 656

Query: 620 TPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDD 679
            P GR+A  P   G +P  G D +G  A + SVA +P +    G      + P+ +  ++
Sbjct: 657 LPSGRKAWMPLADGISPNGGTDVEGPAAVIKSVASIPHSRYTQGTLLNMKLEPDMVKTEN 716

Query: 680 EVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVR 739
            +R+  L  L+      +       H+  NV+++E LL A + PE Y  L +RV+GY   
Sbjct: 717 GIRQ--LMALLRSLCTLDV-----YHVQFNVIDKETLLAAQKKPENYKGLLVRVAGYTAY 769

Query: 740 FNSLTKEQQQDVITRT 755
           F  L +E Q ++I RT
Sbjct: 770 FTELGREVQDEIIART 785


>UniRef50_Q18AX8 Glycerol dehydratase n=8 Tax=Clostridium RepID=Q18AX8_CLOD6
          Length = 790

 Score =  156 bits (394), Expect = 3e-36,   Method: Compositional matrix adjust.
 Identities = 135/547 (24%), Positives = 249/547 (45%), Gaps = 51/547 (9%)

Query: 246 SGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEM 305
           + P TN  EAIQ+ +F  L  + S+N  A++ GR   ++  Y E D + GKITE EAQE+
Sbjct: 251 ANPPTNFYEAIQFVWFVQLGGILSENPLALNLGRFDQYMYPYYENDAREGKITESEAQEL 310

Query: 306 VDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMG 365
           ++ L +KL    +  +      F+G   +   ++GG   +G       S+  L    ++ 
Sbjct: 311 IEALWIKLSEWVWTISANTANYFAGYNQFQNLTVGGKKRNGTDGTNDISYMCLKATESV- 369

Query: 366 PSPEPNMTILWSEKLPLNFKKFAAKVSIDTSSLQYENDD------LMRPDFNND---DYA 416
            + +P +++  S+  P NF    AK+    +     + D      L++  ++ +   D++
Sbjct: 370 KTHQPGLSVRVSQGAPDNFVMAVAKLVKQGTGFPAIHSDSAGAQMLLQDGYDAEDARDWS 429

Query: 417 IACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEV 476
              CV P              N A  + YA+N G       ++G  ++ I  +  +++E+
Sbjct: 430 NCGCVVPHFRKTGQWTSAVNINFAAALEYAMNEGKSRLTGEKMGLDTKNIT-EFTSFEEL 488

Query: 477 MERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDV--------------IRT 522
            +     + +L K  +    +   +H +      L    D  +              I  
Sbjct: 489 KDEFLKQLAYLVKSSVIGTTVAQQIHKEMVPRPFLSTCVDGCLDKGVDLSKGGAKYNIGP 548

Query: 523 MACGIAGLSVAADSLSAIK---YAKVKPIRDEDGLAIDFEIEG---------EYPQFGNN 570
           +  GI GL V ++SL+AIK   +       +E   A++ + EG         + P++GN+
Sbjct: 549 VLTGI-GLGVVSNSLAAIKKLVFEDKVTTLEELTKALNNDWEGYEELRKLALDVPKYGND 607

Query: 571 DPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQ---SVLTITSNVVYGKKTGNTPDGRRAG 627
           +  VD LA+++ + +  + +K   Y+D   ++   + + I++ V  GK  G TP GR+A 
Sbjct: 608 NDYVDSLAIEVSDFYYTETRK---YKDIFGSKFNSAFMGISNYVPTGKIVGATPCGRKAT 664

Query: 628 APFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLA 687
            P   G +P  G D    +A++ S +K+       G      +  + +  +  +R  NL 
Sbjct: 665 KPLTEGVSPFVGTDTTSPLAAMKSASKINHDVHTGGTLLNLRLNQDLVETERGLR--NLT 722

Query: 688 GLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQ 747
            ++  YF       GG H+  N ++ + LL A ENPE+Y  L +RV+GY+ +F +L++E 
Sbjct: 723 SMIKSYFAL-----GGFHVQFNTISNDTLLKAQENPEEYKDLLVRVAGYSTQFVNLSREM 777

Query: 748 QQDVITR 754
           Q  +I R
Sbjct: 778 QDAIIAR 784


>UniRef50_B2TMN7 Formate C-acetyltransferase n=13 Tax=Bacteria RepID=B2TMN7_CLOBB
          Length = 803

 Score =  153 bits (387), Expect = 2e-35,   Method: Compositional matrix adjust.
 Identities = 148/561 (26%), Positives = 244/561 (43%), Gaps = 68/561 (12%)

Query: 246 SGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEM 305
           + PA    EA Q  +F         NG A+S  R   ++  Y + D+     T++   E+
Sbjct: 256 ANPAETFYEACQSFWFVQAIISLESNGHAISPARFDQYMYPYYKNDIDNKFATKEVNTEI 315

Query: 306 VDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMG 365
           +  L +K   +  +R     + FSG  ++    +GG   DG+    + S+  L    ++ 
Sbjct: 316 LHCLWVKFNDLTKVRDETTTKAFSGYSMFQNLIVGGQTPDGKDATNELSYMCLEATGSL- 374

Query: 366 PSPEPNMTI-LWSEKLPLNFKKFAAKVS-IDTSSLQYENDDLMRPDFNND--------DY 415
             P+P++ + +WS K P  F     +++ + T    + ND+++ P   N         DY
Sbjct: 375 KLPQPSLCVRIWS-KTPDEFLIRTCELTRLGTGLPAFYNDEVVIPTLINQGLTIEDARDY 433

Query: 416 AIACCVSPMIVGKQMQFF-GARANLAKTMLYAINGGVDEKLK-MQVGPKSEPIKGDVLNY 473
           AI  CV P   GK   ++  A  NLAK +  ++N G   +L   QVGP++        N 
Sbjct: 434 AIVGCVEPQKPGKTDGWYDAAFFNLAKILELSMNNG---RLNGRQVGPETGEFTS-FKNI 489

Query: 474 DEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRT----------- 522
           D+ +      +++     + A N +   H + +    L ++ D D I T           
Sbjct: 490 DDFINAYKKQIEYFVFHMVAADNCVDIAHAERAPLPFLSSMLD-DCIGTGKSIQEGGGHY 548

Query: 523 -----MACGIAGLSVAADSLSAIK----------YAKVK-------------PIRDEDGL 554
                +  GIA +    DS  AIK            K+K             PI+  +  
Sbjct: 549 RFSGPLGVGIANV---GDSFMAIKKLIFDENKITLLKLKSAVDSNFGENEDDPIKKAEYE 605

Query: 555 AIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYG 614
            I   I    P+FGN+   VD+   D    + K++ K    R       +  +++NV  G
Sbjct: 606 DIKQLILNRVPKFGNDIDEVDEFTRDGALIYCKEVLKYTNQRGGKFIPGLYPVSNNVYLG 665

Query: 615 KKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNA 674
              G TPDGR A  P   G +P  G D  G  A+  SV+KL    A  G  +     PN+
Sbjct: 666 SLVGATPDGRSAFKPLADGVSPTRGADVNGPTAAANSVSKLEHFAAPSGTLFNQKFNPNS 725

Query: 675 LGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVS 734
           L  D+ ++  NL  L+  YF  +     G H+  NV+++++L++A ++PE+Y  L +RV+
Sbjct: 726 LQGDNGLK--NLGSLIRSYFDRK-----GMHIQFNVIDKKVLVEAQKHPEQYRDLIVRVA 778

Query: 735 GYAVRFNSLTKEQQQDVITRT 755
           GY+ +F  L K  Q D+I RT
Sbjct: 779 GYSAQFICLDKGVQDDIIKRT 799


>UniRef50_B8G188 Pyruvate formate-lyase n=1 Tax=Desulfitobacterium hafniense DCB-2
           RepID=B8G188_DESHD
          Length = 796

 Score =  152 bits (385), Expect = 4e-35,   Method: Compositional matrix adjust.
 Identities = 139/549 (25%), Positives = 243/549 (44%), Gaps = 53/549 (9%)

Query: 248 PATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVD 307
           PA N  +A+Q  +F  L      NG ++S GR   ++  Y      A +  +   +E++ 
Sbjct: 263 PAQNFWQALQALWFVQLVLHLESNGHSVSPGRFDQYMYPYY-----AAETDKDACEELLH 317

Query: 308 HLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPS 367
            L +K   +  +R      +F G P++    +GG   +G + V + S   L     +   
Sbjct: 318 CLWLKFFELNKIRNKVSSVVFGGYPMFQNIVVGGQNANGESAVNELSHLCLEATAKVH-L 376

Query: 368 PEPNMTILWSEKLPLNFKKFAAKV-SIDTSSLQYENDDLMRPDF--------NNDDYAIA 418
           P+P++++ W    P  F + A +V S  T      ND+++ P+            DYAI 
Sbjct: 377 PQPSLSVRWFYGCPEEFIRHALEVVSYGTGMPALFNDEVIIPNMLQLGYTIEEARDYAII 436

Query: 419 CCVSPMIVGKQMQFF-GARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVM 477
            C    +  K   F  G   N+ K +   I  G D   + Q   +S  ++     ++E  
Sbjct: 437 GCTEMNVPHKTEPFLTGGFLNILKILELTIFDGFDPVSQTQQAFQSGCVES-FTTFEEFQ 495

Query: 478 ERMDHFMDWLAKQYITALNIIHYMHDKYS---YEASLMA---------LHDRDVIRTMAC 525
           +     + +  +Q++T  NI+  +H K     +E+ L++         L       T   
Sbjct: 496 KAYYEQLSYYLRQHVTCDNILDALHGKICPTPFESMLLSDCLENGKSNLEGGARYNTTTL 555

Query: 526 GIAGLSVAADSLSAIK----------YAKVKPIRD---EDGLAIDFEIEGEYPQFGNNDP 572
            + G++  ADSL+ IK          + ++K       ED   +   I    P++GN+  
Sbjct: 556 QLVGMANVADSLATIKKLIYVEKSLTWNQLKAALQNNYEDDELLRQRIINHVPKYGNDHD 615

Query: 573 RVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGP 632
            VD L  D+V    ++  K  + R+     +V T+ +NV++  K G TPDGR+ G+    
Sbjct: 616 FVDRLGRDVVYHCCREAAKYRSPRNGTYNIAVYTLATNVLWASKVGATPDGRKMGSVLAD 675

Query: 633 G-ANPMHGRDQKGAVASLTSVAKL-PFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLM 690
           G  +  HG D+ G  A   SV K+ P+      +     + P++  + D  +KT    ++
Sbjct: 676 GGVSCSHGMDKNGLTALFNSVRKIDPYKPLGSAL-LNIRLSPSSFNETD-FQKT--VDVV 731

Query: 691 DGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQD 750
             +F ++     GQH+  NV +   L DA +NPEKYP L +RV+G++V F ++    Q+D
Sbjct: 732 KSFFMNK-----GQHVQFNVFDVNALRDAQKNPEKYPLLMVRVAGFSVLFTTIETILQED 786

Query: 751 VITRTFTQS 759
           +I RT   S
Sbjct: 787 IINRTLHSS 795


>UniRef50_B0G487 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=B0G487_9FIRM
          Length = 803

 Score =  152 bits (383), Expect = 7e-35,   Method: Compositional matrix adjust.
 Identities = 166/673 (24%), Positives = 276/673 (41%), Gaps = 117/673 (17%)

Query: 172 AYGRGRIIGDYRRVALYG--------------IDYLMKDKLAQFTSLQA-DLENGVNLEQ 216
           A G G  I DY+ V   G              ID L  D L Q   L+A  L N   L  
Sbjct: 155 AAGLGNEIVDYKMVVEKGLEDVLTRIQEKKDSIDILDPDALKQLHFLEAAKLGNEAVLNY 214

Query: 217 TIRLREEIAEQ------HRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQ 270
           + RL ++  E+           ++ E+A    Y    PA   QEA+Q  +   LA     
Sbjct: 215 SNRLADKCEEEAGKTDDSEYKKELMELAEICRYVPFHPARTFQEAVQSIFMVLLAVHMES 274

Query: 271 NGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSG 330
           NG A+S GR   ++    ++D++ G+IT+++A E+++   +K   +  LR+    E F G
Sbjct: 275 NGHAISLGRFDQYVYPLYKKDIEEGRITKEKALEIIECFFIKCNELNKLRSWPDTEFFMG 334

Query: 331 DPIWATESIGGMGLDGRTL---VTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKF 387
             ++   +I G  ++G+     +++   +    L  + PS                F   
Sbjct: 335 YQMFINLAICGQTVEGKDATNDISRMCIQACRELKLITPSVSVKC-----------FDGT 383

Query: 388 AAKVSIDTSSLQYENDDLMRPDFNND------------------DYAIACCVSPMIVGK- 428
             +V +D      E+   M P F ND                  D+    C+   I GK 
Sbjct: 384 TDEVLMDALEATIEHKGGM-PAFYNDKAFIKILREMGVAEEDLVDWCPDGCIEASIPGKW 442

Query: 429 QMQFFGARANLAKTMLYAINGGVDEKLKMQV-GPKSEPIKGDVLN--YDEVMERMDHFMD 485
                G   ++ K +   +N G D         P  + +    +   ++E  + + +F+D
Sbjct: 443 DFAAKGPWLSIEKVLEITLNNGKDPATGTVFRKPDKDIVASSSMEDIFEEYKKTLKYFLD 502

Query: 486 W-LAKQYITALNIIHYMHDKYSYEASLM--------------ALHDRDVIRTMACGIAGL 530
                ++I   + +H  +D  ++ +SL+              AL+  D   T     AG 
Sbjct: 503 LNCLTEHIN--DEVHVRYDLNAFRSSLVQDCIGRCLDLVEGGALYSADGGPT-----AGT 555

Query: 531 SVAADSLSAIKY---------------AKVKPIRDED----GLAIDFEIEGEYPQFGNND 571
             A D+L+ I+Y               A      DE     G  I   ++ + P+FGN+D
Sbjct: 556 ISAGDALTGIEYLVFDKKILTMEQLLHACATNFEDESTTPTGKEIQMIMKNKVPKFGNDD 615

Query: 572 PRVDDLAVDLVERFMKKIQKLHTYRDA------IPTQ---SVLTITSNVVYGKKTGNTPD 622
              D   V + E     +   H Y+ +      +P     S   +T N+ +G + G TPD
Sbjct: 616 DYADKWVVAIEEYVGHSLN--HDYKSSKYGKGPVPCCFAYSQTPVTGNISFGSRIGATPD 673

Query: 623 GRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVR 682
           GR AG P   G +P +G ++ GA A+  SVAK+P  Y + G  +   + P+ +   +  +
Sbjct: 674 GRSAGEPVNNGVSPANGSERNGATAACNSVAKIPTIYDQKGNIFNMRLAPSTIANQESRQ 733

Query: 683 KTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNS 742
           K  +  +M   F  +A     + +  NV++ E+L +A + PE +P L +RVSGY+  F S
Sbjct: 734 K--ILDMMRALFDKDA-----EQIQFNVVDNEVLKEAQKRPEDFPDLMVRVSGYSALFTS 786

Query: 743 LTKEQQQDVITRT 755
           L    Q DVI RT
Sbjct: 787 LGVACQNDVINRT 799


>UniRef50_C0QGR8 PflD1 n=1 Tax=Desulfobacterium autotrophicum HRM2
           RepID=C0QGR8_DESAH
          Length = 788

 Score =  148 bits (373), Expect = 1e-33,   Method: Compositional matrix adjust.
 Identities = 139/549 (25%), Positives = 238/549 (43%), Gaps = 70/549 (12%)

Query: 254 EAIQWTYFGYLAAVKSQNG-AAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMV------ 306
           E +Q ++F ++  +   NG  A + G        Y ++ L+ G++ E+ A+E++      
Sbjct: 257 EVLQMSWFMHIGVITESNGWDACNPGHVDRHFFPYYKKSLETGQLDEESAKELLCAWWIK 316

Query: 307 --DHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTM 364
             +H       V  L +  Y++       +   S+GG+  DG+  V   S+ FL  L  +
Sbjct: 317 YNNHPAPAKYGVSALESGTYND-------FVNISLGGITTDGKDAVNDLSYIFLEILDEI 369

Query: 365 GPSPEPNMTILWSEKLPLNFKKFAAKV---------SIDTSSLQYENDDLMRPDFNNDDY 415
               +P + +L S   P +F K A KV           +  ++  +   + +   +    
Sbjct: 370 -EFIQPQVHVLLSRMNPEHFLKEACKVIRKGRGFPAMFNAEAVIEQQLRVGKTISDARGG 428

Query: 416 AIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDE 475
            I  CV     GK+        N+AK +   +  G D + K QVGPK+  +K D  +Y+E
Sbjct: 429 GICGCVETTCYGKEAAPLIGYINIAKILELTLQNGFDTRTKKQVGPKTGNVK-DFNSYEE 487

Query: 476 VMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIR-------------T 522
           +ME       ++    +     +  M  KY  +  L  L +  V               +
Sbjct: 488 LMEAFKKQARYIIDTKLVGSQYLIQMFAKYVPQPFLSVLIEGCVESGKDYNDGGPKYNVS 547

Query: 523 MACGIAGLSVAADSLSAIKYAKVKPIRDEDGLAIDFEIEG-----------------EYP 565
           +  G+ G+    DSLSAIK    K + DE   ++   IE                  + P
Sbjct: 548 ILPGV-GIGTVTDSLSAIK----KHVFDESTYSMGEVIEALNADWQKSEEMRLTFANKTP 602

Query: 566 QFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRR 625
           ++GN++   D +  ++ + F+  +  +   R      ++L  T ++ +G+ TG T DGRR
Sbjct: 603 RYGNDNDYADSIMREVSDFFIDTVDGIKDSRGGTYRMNMLPTTCHMYFGEVTGATCDGRR 662

Query: 626 AGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTN 685
           AG P   G +P+ G D  G  ASL S AK+  +    G       +P+ L  D  + K  
Sbjct: 663 AGKPLSEGISPVQGADLCGPTASLKSAAKMDHSRTC-GTLLNMKFLPDVLKGDIGIHK-- 719

Query: 686 LAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTK 745
           LA L+  YF +     GG H+  NV + + L  A + PE Y  L +RV+GY+  FN++ K
Sbjct: 720 LASLIRTYFTY-----GGHHIQFNVCDAKTLQLAQKTPEDYNDLIVRVAGYSDYFNAIGK 774

Query: 746 EQQQDVITR 754
           + Q ++I R
Sbjct: 775 DLQDEIIQR 783


>UniRef50_D1AFQ7 Pyruvate formate-lyase n=3 Tax=Fusobacteriaceae RepID=D1AFQ7_SEBTE
          Length = 802

 Score =  147 bits (372), Expect = 1e-33,   Method: Compositional matrix adjust.
 Identities = 139/550 (25%), Positives = 243/550 (44%), Gaps = 62/550 (11%)

Query: 254 EAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQE-AQEMVDHLVMK 312
           EA+Q  +F +L      NG + S GRT  +L  + ++D+   K  ++E A+E++  L +K
Sbjct: 263 EAVQLIWFIHLVIQIESNGHSASLGRTDQYLYEFYKKDVITDKTMDREFAKELLQCLWVK 322

Query: 313 LRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNM 372
           L  V  +R   +    +G P +   +IGG   DG     + ++  L ++       +PN+
Sbjct: 323 LYTVIKVRPTSHSGYGAGYPTYQNVTIGGSNYDGSDACNELTYLILESV-AENKMTQPNL 381

Query: 373 TILWSEKLPLNFKKFAAKVSIDTSSL-QYENDDLMRPDFNND--------DYAIACCVSP 423
            + +    P  F + +A V+     +     D+++ P   N         +Y +  CV  
Sbjct: 382 AVRFHSNSPEKFIRESASVAATGYGMPAMHTDEIIIPALLNKGVEFKDAYNYTMVGCVEV 441

Query: 424 MIVGKQMQFFGARA------NLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVM 477
            + GK    +G R       N  K +   IN G D +  M +   +  +  D  ++D++ 
Sbjct: 442 AVPGK----WGYRCTGMTFLNFIKIVELVINDGHDPRTGMTLYQGNGTLL-DFESFDDLW 496

Query: 478 ERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACG--------IAG 529
           +  +  + +  +  + AL+++   H +   +    +L D  + R             IAG
Sbjct: 497 KSWEKNIAYYTRLSV-ALDVLADTHLEELPDILCSSLIDSCIERGKTAKEGGAKYDIIAG 555

Query: 530 LSVAADSLSAIKYAKVKPIRDE---------DGLAIDFE-IEGE--------YPQFGNND 571
           L V   + +   YA  K + ++         + L  +FE I+GE         P++GN+ 
Sbjct: 556 LQVGLSNAANAMYALKKTVFEDKVLTKEEVFEALKNNFEGIDGERVRNILLNVPKYGNDI 615

Query: 572 PRVDDLAVDLVERFMKKIQKLHTYR------DAIPTQSVLTITSNVVYGKKTGNTPDGRR 625
             +D   V   E ++++I K    R      +     S   I+SNV  G  TG TPDGR 
Sbjct: 616 DEIDRFTVKTYEPYIEEIAKYKNTRYGRGPINGGYGLSTSGISSNVPMGTVTGATPDGRY 675

Query: 626 AGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTN 685
           A  P   GA+P  G D KG  A L S+ KLP      G        P+ +  +D+  K  
Sbjct: 676 AYTPAAEGASPTQGTDVKGPTAVLNSIVKLPTLLITGGQLLNQKYSPDLIKSEDQFEK-- 733

Query: 686 LAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTK 745
             G++  + + +     G H+  N+++R+ L  A E+PEKY  + +RV+GY  +F +L  
Sbjct: 734 FVGIIKTFINLK-----GWHIQFNIISRDTLQAAKEDPEKYRDIVVRVAGYCAQFVTLDP 788

Query: 746 EQQQDVITRT 755
             Q+D+I RT
Sbjct: 789 ITQEDIIART 798


>UniRef50_C6A251 Pyruvate-formate lyase n=50 Tax=cellular organisms
           RepID=C6A251_THESM
          Length = 823

 Score =  147 bits (371), Expect = 1e-33,   Method: Compositional matrix adjust.
 Identities = 157/588 (26%), Positives = 263/588 (44%), Gaps = 81/588 (13%)

Query: 222 EEIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGA-AMSFGRT 280
           E+  ++ + L QM E+  +       P T   EA+Q  +F ++      N   + + GR 
Sbjct: 258 EKDPKRKKELKQMAEICKRV--PAHAPRT-FWEALQHYWFVHVGVTYETNPWDSFNPGRI 314

Query: 281 STFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEY-------DELFSGDPI 333
              L  + +RDL+ G++T ++A+E++    +K     F   P         +E F+ +  
Sbjct: 315 DQHLYPFYKRDLEEGRLTREKAKELLQCFWLK-----FNNQPAVPKVGVTAEESFTYND- 368

Query: 334 WATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKV-S 392
           ++  ++GG+  DG   V + S+  L  L  M  + +PN  +L S K P  F   A KV  
Sbjct: 369 FSKLNLGGLKKDGSDGVNELSYLILEVLSEMR-TLQPNTAVLISNKNPDRFLIEALKVVG 427

Query: 393 IDTSSLQYENDD-----LMRPDFNNDD---YAIACCVSPMIVGKQMQFFGARANLAKTML 444
                  + N D     ++R     +D     ++ CV     GK+        NL K + 
Sbjct: 428 PGFGEPPFFNFDGVIVKMLRQGKTLEDARTSGVSGCVETGAFGKEAYILTGYFNLPKILG 487

Query: 445 YAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVME-------RMDHFMDWLAKQYITALNI 497
             +N G+D +   ++G ++    GD  N+    E       +++HF+D   K      +I
Sbjct: 488 ITLNNGIDPRTGKKIGIET----GDPRNFKSFEELWNAFVKQVNHFLDIKMK----GNDI 539

Query: 498 IHYMHDKYSYEASLMALHDRDVIR-------------TMACGIAGLSVAADSLSAIKYA- 543
           I  ++ KY      M+L   D ++             T    + GL   ADSL+AIKY  
Sbjct: 540 IETLYAKY-LPVPFMSLWIEDCVKNAKDYNGGGTRYNTQYIQVVGLGTIADSLAAIKYHV 598

Query: 544 --KVKPIRDEDGLAIDFEIEG------------EYPQFGNNDPRVDDLAVDLVERFMKKI 589
             K   + +E   A+    +G            + P+FGN+D  VD++A  +V+  +  I
Sbjct: 599 FDKKTFVMEELLNALKNNWKGYEMMREILRNPEKTPKFGNDDEYVDEIAKKVVDTVVDLI 658

Query: 590 QKL--HTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVA 647
           +       R A      L  T +V +GK TG TPDGR AG P   G +P+ G D+KG  A
Sbjct: 659 EAYPPSPVRKASKRAYFLPTTVHVYFGKVTGATPDGRDAGFPVSEGISPVQGMDRKGIAA 718

Query: 648 SLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLN 707
              SVAK  +     G      + P+    ++ ++K  LA L+  +F       GG H+ 
Sbjct: 719 VFRSVAKCDWD-KTGGALLNQKLTPDLFDNEENIKK--LAQLIRTFFRL-----GGHHVQ 770

Query: 708 VNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRT 755
            NV++ E+L +A + P+++  L +RV+GY+  F +L K  Q ++I RT
Sbjct: 771 FNVISAELLREAQKRPQEFQDLMVRVAGYSDYFVNLPKGLQDEIIART 818


>UniRef50_B5XXR3 Formate C-acetyltransferase 2 n=9 Tax=cellular organisms
           RepID=B5XXR3_KLEP3
          Length = 765

 Score =  147 bits (370), Expect = 2e-33,   Method: Compositional matrix adjust.
 Identities = 161/639 (25%), Positives = 281/639 (43%), Gaps = 81/639 (12%)

Query: 174 GRGRIIGDYRRVALYGIDYLMKD------KLAQFTSLQADLENGVNLEQTIR-------L 220
           G+G II DY R+  +G+  L+ +      +  +    QA L   + LE + R       L
Sbjct: 153 GQGHIIIDYPRLLNHGLGALVAELKTHCARQPENPFYQAVL---ILLEASQRHILRYAAL 209

Query: 221 REEIAEQHRALGQMKEM---AAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSF 277
            EE+A   +   + +E+   AA   ++     T+  +A Q  ++  +      N +++S 
Sbjct: 210 AEEMAGHFQDPQRQQELLTIAAISRHNAQHRPTDFPQACQLFWYMNIILQYESNASSISL 269

Query: 278 GRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATE 337
           GR   ++  + +  L  G+      +E+++ L +K   +  LR+      F+G P   T 
Sbjct: 270 GRFDQYMLPFYQASLNQGQ-DPAYLKELLESLWVKCNDIVLLRSSSSARYFAGFPTGYTA 328

Query: 338 SIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNF-KKFAAKVSIDTS 396
            +GG+   GR+ V + SF  L+  Y     P+PN+ +  +E +   F +K A  + + T 
Sbjct: 329 LLGGLTDTGRSAVNELSFLCLDA-YQNVQLPQPNLGVRVNELIDRPFLRKTAETIRLGTG 387

Query: 397 SLQYENDDLMRPDFNND--------DYAIACCVSPMIVGKQMQFFG-ARANLAKTMLYAI 447
             Q  ND+++ P F N         DYA+  CV   I G+       A  NL K M    
Sbjct: 388 IPQIFNDEVVVPAFLNRGVSLEDARDYAVVGCVELSIPGRTYGLHDIAMFNLLKVM---- 443

Query: 448 NGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSY 507
                 ++ +Q       +  D L   ++ +++ H++    K  +   NI    H  ++ 
Sbjct: 444 ------EIVLQENEHQPDVTWDGL-ICQIRDKIRHYI----KLMVEGSNICDIGHRDWAP 492

Query: 508 EASLMAL------HDRDVI----RTMACGIAGLSVA--ADSLSAIK-------------- 541
              L +       H +D+     R    G+ G+ +A  +DSL A+K              
Sbjct: 493 VPLLSSFIEDCVQHGKDITAGGARYNFSGVQGIGIANLSDSLYALKGMVFDQQRLSFDQL 552

Query: 542 YAKVKP-IRDEDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIP 600
            A +K   +  +G  I   +   + ++GN+   VD+++ DL+  + K++++    R    
Sbjct: 553 MAVLKANFQTPEGEKIRARLINHFDKYGNDIDDVDNISADLLRFYCKEVEQYLNPRGGHF 612

Query: 601 TQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGA-NPMHGRDQKGAVASLTSVAKLPFAY 659
           T    T++++V  G   G TPDGR AG     G  +PM G+D +G  A L SV+KL    
Sbjct: 613 TPGSYTVSAHVPLGSVVGATPDGRLAGEQLADGGLSPMVGQDSQGPTAVLKSVSKLDNYL 672

Query: 660 AKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDA 719
             +G        P  L  D  + K  LA  +  +   +      QH+  NV+N + L +A
Sbjct: 673 LSNGTLLNVKFTPATLAGDGGLNK--LADFLQAFCKLKL-----QHIQFNVVNADTLREA 725

Query: 720 MENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQ 758
            + P+ +  L +RV+GY+  F  L+KE Q D+I RT  Q
Sbjct: 726 QQRPQDFAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQ 764


>UniRef50_B8FFL2 Formate C-acetyltransferase n=1 Tax=Desulfatibacillum alkenivorans
           AK-01 RepID=B8FFL2_DESAA
          Length = 803

 Score =  143 bits (361), Expect = 2e-32,   Method: Compositional matrix adjust.
 Identities = 143/581 (24%), Positives = 258/581 (44%), Gaps = 72/581 (12%)

Query: 220 LREEIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGR 279
           L E++A + + + ++     + G      A   +EA+Q  +F  +A        ++  GR
Sbjct: 246 LDEDLAAELKGIAEVCSRVPRKG------AKTFREALQSCFFAQIAINNESLDNSVCPGR 299

Query: 280 TSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMV-----RFLRTPEYDELFSGDPIW 334
              +L  Y E+DLKAG +T +EA+E+     +K+  +     +++ T  +   F+G  + 
Sbjct: 300 MDHYLYPYYEKDLKAGLLTREEAKELAGAFSVKMSEIVPVFSKYI-TRTHGGFFNGQIV- 357

Query: 335 ATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNF-KKFAAKVSI 393
              ++GG   +G+    + +  FL  +  +    +PN T    +  P  +  K    +S 
Sbjct: 358 ---NVGGTHKNGKDSTNELTMIFLEVMDELRMR-QPNYTARVHKNSPKEYLDKVYGILSK 413

Query: 394 DTSSLQYENDDLMRPDFNND--------DYAIACCVSPMIVGKQMQFFGARANLAKTML- 444
             +S    ND+++ P    +        +Y    CV P  V + + F    A L  T + 
Sbjct: 414 GANSPSIYNDEVIVPVLKQNGVKIGDARNYTPVGCVEP--VAQGVSFSSTDAALFNTAII 471

Query: 445 --YAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVME----RMDHFMDWLAKQYITALNII 498
              A+N G       Q+G K++P+   +   ++V E    +M H ++ L K  + A+ I 
Sbjct: 472 LELALNQGRRLGRVAQIGAKTKPVS-QMTCIEDVQEAFEIQMFHGINRLLKD-LQAIEIA 529

Query: 499 HYMHDKYSYEASLM-------ALHDRDVIRTMACGI--AGLSVAADSLSAIKYAKVKPIR 549
           +  +      + L+       A   R   R    GI   GL  A DSL+AIK A    + 
Sbjct: 530 NAEYHPTPLSSMLLDGCLENGACSTRGGARYNFSGIQCVGLVDAGDSLAAIKQA----VF 585

Query: 550 DEDGLAIDFEIEG---------------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHT 594
           ++  L+++  +E                  P+FGN+DP  D      ++ F   +    +
Sbjct: 586 EDKKLSMEELVEHLKNNLSDDRWRHYLLNMPKFGNDDPFADVWTAYALDVFKAALDGKTS 645

Query: 595 YRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAK 654
            R    T  V ++T +  +G      P+GRR G     G +P +G+D+KG  A L S+ +
Sbjct: 646 TRGGKYTVGVYSVTLHEYWGTVVSALPNGRRNGESLSNGMSPSNGQDRKGPTAVLNSMNR 705

Query: 655 LPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNRE 714
           + ++   +GI++      N +G       T +  +   YF       GG    +NV++ +
Sbjct: 706 IDYSKTDNGINFNIKFDANTVGSPAGC--TAMKSIFSTYFKR-----GGMQAQINVLDPK 758

Query: 715 MLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRT 755
           +L++A +NPE YP L +RVSGY+  FN LT   ++++I RT
Sbjct: 759 VLIEARDNPEAYPHLLVRVSGYSAYFNDLTPAMKEEMIRRT 799


>UniRef50_B2TJX0 Formate C-acetyltransferase n=9 Tax=Bacteria RepID=B2TJX0_CLOBB
          Length = 801

 Score =  143 bits (360), Expect = 3e-32,   Method: Compositional matrix adjust.
 Identities = 142/554 (25%), Positives = 248/554 (44%), Gaps = 65/554 (11%)

Query: 251 NAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLV 310
           N  EA+Q  +F +L      NG + S GR   +L  Y +  ++ G +TE  A+E++  L 
Sbjct: 260 NFYEAVQMIWFVHLVIQIESNGHSASLGRVDQYLYPYYKEGIENGTLTEDFAKELLQCLW 319

Query: 311 MKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEP 370
           +KL  +  +R   +    +G P +   +IGG    G       S+  L ++  M  + +P
Sbjct: 320 IKLFSILKIRPTSHAGYGAGYPTYQNVTIGGCNELGEDCTNSLSYLILQSVGEMKLT-QP 378

Query: 371 NMTI-LWSEKLPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNND--------DYAIACCV 421
           N++  L+S       ++ A  +           D+++     N         +Y +  CV
Sbjct: 379 NLSARLFSNSSARFIRECANVIKTGFGMPALHTDEIIVQSLLNKGVNYKDAYNYTMVGCV 438

Query: 422 SPMIVGKQMQFFGARA------NLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVL---N 472
              + GK    +G R       N+ K +   +N G DE+     G        D+L   N
Sbjct: 439 EVAVPGK----WGYRCTGMSFLNMIKAVELTLNDGYDER----TGETLLTGNRDLLSFNN 490

Query: 473 YDEVMERMDHFMDWLAKQYITALNIIHYMHDKYS--YEASLM--------ALHDRDVIRT 522
           ++E+    +  + +  K  +    I     +++   + +SL+        ++ +   I  
Sbjct: 491 FEELWAAWEKNIAYYTKLTVALDKIADTNLEEFPDIFCSSLVDDCIGRGKSIKEGGSIYD 550

Query: 523 MACGI-AGLSVAADSLSAIK---YAKVKPIRDE--DGLAIDFE-IEG--------EYPQF 567
           +  G+  GL+ A +SL A+K   + K    ++E  + L  +FE +EG          P++
Sbjct: 551 IVAGLQVGLANATNSLFALKDVIFDKNILSKEEVVNALKNNFEGLEGIKVKKILFSSPKY 610

Query: 568 GNNDPRVDDLAVDLVERFMKKIQKLHTYR------DAIPTQSVLTITSNVVYGKKTGNTP 621
           GN+   VD++A ++ + ++ +I K  T R        I   S   I+SNV  G  TG TP
Sbjct: 611 GNDIDCVDNMARNVYQTYINEISKYKTTRYGRGPIGGIYGLSTSGISSNVPMGCVTGATP 670

Query: 622 DGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEV 681
           DGR A  P   GA+P+ G D +G  + L S+ KLP      G        PN L  DD+ 
Sbjct: 671 DGRFAWTPAAEGASPVQGSDIEGPTSVLKSITKLPTILMTGGQLLNMKFSPNLLVGDDQF 730

Query: 682 RKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFN 741
             T    L+  +   +     G H+  NV++ + L +A ++PEKY  + +RV+GY  +F 
Sbjct: 731 --TKFINLIKSFVSMK-----GWHIQFNVIDTKTLREAQKDPEKYRDVIVRVAGYCAQFV 783

Query: 742 SLTKEQQQDVITRT 755
           +L +  Q+D+I+RT
Sbjct: 784 TLDQTTQEDIISRT 797


>UniRef50_C7X781 Pyruvate formate-lyase n=3 Tax=Bacteroidales RepID=C7X781_9PORP
          Length = 810

 Score =  142 bits (359), Expect = 4e-32,   Method: Compositional matrix adjust.
 Identities = 171/702 (24%), Positives = 297/702 (42%), Gaps = 103/702 (14%)

Query: 126 YNRELDPMIK------KIFT----EYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYG- 174
           Y RE+ P  K      +IF+    E+++ +  G+F  +     R      L G    YG 
Sbjct: 135 YEREVIPYWKGRTQRERIFSHVPKEWKEAYEVGMFTEFMEQ--RAPGHTALDGKVYQYGL 192

Query: 175 ---RGRIIGDYRRVALYGIDYL----MKDKLAQFTSLQADLENGVNL-EQTIRLREEIA- 225
              + RI G+     L  +D++      DK  + T++    +  + L E+   L +E++ 
Sbjct: 193 LDLKKRIEGE-----LSALDFMNDPEATDKQEELTAMSISCDAAILLAERHADLADEMSL 247

Query: 226 --EQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNG-AAMSFGRTST 282
             +  R   +++++A    +  +       EAIQ  +F +L  +   NG  AM+ G    
Sbjct: 248 TEKDPRRAAELRKIAEVCRWVPAHAPRTYWEAIQMYWFVHLGTITELNGWDAMNPGHFDQ 307

Query: 283 FLDVYIERDLKAGKITEQEAQEMVDHLVMKLRM--------VRFLRTPEYDELFSGDPIW 334
            L  + E+++ AG +T  EA+E++    +K+          +    +  Y++       +
Sbjct: 308 HLAPFYEKEIAAGTLTRDEAKELMSCFFIKVNNHTAPPKVGITAKESGTYND-------F 360

Query: 335 ATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKV--- 391
              +IGG+  DG   V++ S+  L T+  +    +P   I  S + P  F +   KV   
Sbjct: 361 TNLNIGGIRADGSDGVSEVSYIMLETIEELHIL-QPGSAIHVSARTPERFLRAGCKVIRQ 419

Query: 392 -----SIDTSSLQYENDDLMRPDFNNDDY---AIACCVSPMIVGKQMQFFGARANLAKTM 443
                S+    +  +  +LMR   +  D      + C+     GK+        N+ K +
Sbjct: 420 GHGYPSVFNPDVYVQ--ELMRQGKSLRDAREGGCSGCIEVGAFGKEAYVLTGYLNVPKIL 477

Query: 444 LYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHD 503
              ++ GVD     +VG ++   +G    Y+E+       + +     +   N I  M  
Sbjct: 478 EVTLHNGVDPVSGRKVGLETGDPRG-FRTYEELYAAFMRQIHYFVDMKVRVSNYIDRMFA 536

Query: 504 KYSYEASLMALHDRDVIRT----MACG---------IAGLSVAADSLSAIKYAKVKPIRD 550
           KY+  A+ ++L   D I        CG           GL    DSLS+++    K + +
Sbjct: 537 KYA-PATFLSLFIDDCIAKGKDYYNCGPRYNTTYIQCTGLGTITDSLSSLR----KHVFE 591

Query: 551 E---------DGLAIDFE--------IEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLH 593
           +         D +A +FE        I    P FGN+DP  D +AV + +     I+   
Sbjct: 592 DKTFTMEALLDAMADNFEGHEPMRQMILNRTPFFGNDDPYADQIAVRVFDDLYDAIEGKP 651

Query: 594 TYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVA 653
             +      ++L+ T +V +GK  G TP+GR AG     G +P HG D  G  A + S+ 
Sbjct: 652 NTKGECFHLNMLSTTCHVYFGKVMGATPNGRLAGRAISDGTSPSHGADIHGPSAVIKSLG 711

Query: 654 KLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNR 713
           KL       G       +P+ L +++++ K  LA L+  YF       GG H+  N+++ 
Sbjct: 712 KLD-QVKSGGTLLNQRFLPSLLWREEDISK--LASLIRSYF-----ALGGHHIQFNIVDT 763

Query: 714 EMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRT 755
           E L  A + PE Y  L +RV+GY+  FN +  + Q DVI RT
Sbjct: 764 ETLYAAQKCPEDYRDLLVRVAGYSDYFNDMNADLQADVIART 805


>UniRef50_Q7NEY2 Glr3745 protein n=1 Tax=Gloeobacter violaceus RepID=Q7NEY2_GLOVI
          Length = 460

 Score =  141 bits (355), Expect = 1e-31,   Method: Compositional matrix adjust.
 Identities = 79/182 (43%), Positives = 109/182 (59%), Gaps = 12/182 (6%)

Query: 219 RLREEIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFG 278
           RLR  +  Q  A+  ++ +A  YG DI  PA  AQ+AIQWTY   LA      G   S  
Sbjct: 192 RLRR-LGMQLGAVETVEALAGCYGLDIGRPAATAQQAIQWTYLALLATRDPLFGRRRSVT 250

Query: 279 RTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATES 338
              TF DVY +RDL  G + E+EAQE+VD L++KLR+ +    P   EL+   P+ A   
Sbjct: 251 GLDTFFDVYFQRDLARGLLVEEEAQELVDDLMIKLRLPQ----PTLSELYL--PLAA--- 301

Query: 339 IGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSSL 398
             G+  +GR LVT+  FRF+NT Y +GP+ EP++ +LWS  L   F++F  +V+IDTSSL
Sbjct: 302 --GVDPEGRPLVTRTDFRFVNTCYNLGPAAEPHLLVLWSAALSGAFRRFCGEVTIDTSSL 359

Query: 399 QY 400
           +Y
Sbjct: 360 RY 361



 Score = 53.5 bits (127), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 23/47 (48%), Positives = 28/47 (59%)

Query: 9   ATAWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLW 55
           A  W+GF  G+WQ   +V +FI  N  PY GD+S L G TE T  LW
Sbjct: 78  ADPWQGFRPGNWQVRTDVENFIAANCDPYLGDDSDLTGPTERTQALW 124



 Score = 51.2 bits (121), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 34/106 (32%), Positives = 54/106 (50%), Gaps = 11/106 (10%)

Query: 647 ASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHL 706
           +SL     LP    + G+++TFS  P+ALG     +  NL   +DG          G HL
Sbjct: 357 SSLRYARALPLP--QTGLAHTFS--PDALGATRTEQVENLGLWLDGQPE-------GDHL 405

Query: 707 NVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVI 752
            +NV  RE LL  +  P K+  LT++++  AV  +SL+   ++ V+
Sbjct: 406 GINVFGREALLSTLTRPNKFAHLTVQLAEGAVDLHSLSPLGRRQVL 451


>UniRef50_P32674 Formate acetyltransferase 2 n=80 Tax=Gammaproteobacteria
           RepID=PFLD_ECOLI
          Length = 765

 Score =  140 bits (353), Expect = 2e-31,   Method: Compositional matrix adjust.
 Identities = 135/543 (24%), Positives = 234/543 (43%), Gaps = 62/543 (11%)

Query: 254 EAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKL 313
           +A Q  ++  +      N +++S GR   ++  + +  L  G+      +E+++ L +K 
Sbjct: 246 QACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGE-DAAFLKELLESLWVKC 304

Query: 314 RMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMT 373
             +  LR+      F+G P   T  +GG+  +GR+ V   SF  L+  Y     P+PN+ 
Sbjct: 305 NDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDA-YQSVQLPQPNLG 363

Query: 374 ILWSEKLPLNF-KKFAAKVSIDTSSLQYENDDLMRPDFNND--------DYAIACCVSPM 424
           +  +  +   F  K A  +   T   Q  ND+++ P F N         DY++  CV   
Sbjct: 364 VRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCVELS 423

Query: 425 IVGKQMQFFG-ARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHF 483
           I G+       A  NL K M   ++               E      L Y+ ++E++   
Sbjct: 424 IPGRTYGLHDIAMFNLLKVMEICLH---------------ENEGNAALTYEGLLEQIRAK 468

Query: 484 MDWLAKQYITALNIIHYMHDKYSYEASLMAL------HDRDVI----RTMACGIAGLSVA 533
           +       +   NI    H  ++    L +         RD+     R    G+ G+ +A
Sbjct: 469 ISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIA 528

Query: 534 --ADSLSAIK---YAKVKPIRDE------------DGLAIDFEIEGEYPQFGNNDPRVDD 576
             +DSL A+K   + + +   DE            +G  +   +   + ++GN+   VD+
Sbjct: 529 NLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDN 588

Query: 577 LAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGA-N 635
           ++ +L+  + K+++K    R    T    T++++V  G   G TPDGR AG     G  +
Sbjct: 589 ISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLS 648

Query: 636 PMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFH 695
           PM G+D +G  A L SV+KL      +G        P  L  +  +RK  LA  +  +  
Sbjct: 649 PMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRK--LADFLRAFTQ 706

Query: 696 HEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRT 755
            +      QH+  NV+N + L +A + P+ Y  L +RV+GY+  F  L+KE Q D+I RT
Sbjct: 707 LKL-----QHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRT 761

Query: 756 FTQ 758
             Q
Sbjct: 762 AHQ 764


>UniRef50_O28823 Pyruvate formate-lyase 2 (PflD) n=1 Tax=Archaeoglobus fulgidus
           RepID=O28823_ARCFU
          Length = 776

 Score =  140 bits (352), Expect = 2e-31,   Method: Compositional matrix adjust.
 Identities = 174/745 (23%), Positives = 312/745 (41%), Gaps = 120/745 (16%)

Query: 95  EKIVGLQTEAPLKRALIPFG-GIKMIEGSCKAYNRELDPMI-----KKIFTE------YR 142
           E IVG     P    + P G G+++I       NRE + ++      K+  E       R
Sbjct: 62  ELIVGTMLPNPPGAIIFPEGVGLRIINELDSLPNRETNRLMVDEEDAKVLREEIAPYWQR 121

Query: 143 KTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFT 202
           KT     F +  PDI++   +G +  L +  G   +  +Y  +   G  + +++   +  
Sbjct: 122 KTIEAFAFPL-MPDIMQILYTGSVFVLTEIAGISHVAVNYPYLLRRGFRWFLEESERRIR 180

Query: 203 SLQADLENGVN--------------LEQTI-------RLREEIAE-----QHRALGQMKE 236
           +L+   E+GV                E  I       +L EE+AE     +   L ++ E
Sbjct: 181 ALE---ESGVYEGEKYSFYQAAKIVSEAVINYGLRYSKLAEELAESEDGERREELLKIAE 237

Query: 237 MAAKYGYDISGPATNAQ---EAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLK 293
           +  K       PA   +   EA+Q+ +    A  +     A+S GR   +L  + ++D+ 
Sbjct: 238 ICRKV------PAEKPETFWEAVQFVWLVQSALHQENYEQAISMGRIDQYLYPFFKKDIG 291

Query: 294 AGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDEL----FSGDPIWATESIGGMGLDGRTL 349
            G+I  + A +++ +L +K   +     P +D L    FSG       +IGG  + G   
Sbjct: 292 EGRINRELAFDILANLWIKTNEI----VPAFDSLLEQYFSGQATNQAVTIGGCDIYGNDA 347

Query: 350 VTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNF-KKFAAKVSIDTSSLQYENDDLMRP 408
             + ++  L     +    +PN+ +  ++  P +F K+ A  +S   ++L    DD    
Sbjct: 348 TNELTYLMLEVTDRLRLR-QPNVHVRINKGSPESFLKRLAEAISSGCNNLALFFDDAAVK 406

Query: 409 DFNN---DD-----YAIACCVSPMIVGKQMQFF-GARANLAKTMLYAINGGVDEKLKMQV 459
              N   DD     Y    CV     G        A  N+AK + YA+N GVD +   + 
Sbjct: 407 ALKNAEVDDRDALNYTTDGCVEIAPFGNSFTSSDAALINVAKALEYALNEGVDLQFGYEF 466

Query: 460 GPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDV 519
           G K+E  K      ++++E++   +  + K  +   N++ Y + +      L++L   D 
Sbjct: 467 GAKTEKPKF----LEDLLEKLREQVSHIVKLVVRGSNVLSYANAEVK-PTPLLSLCVEDC 521

Query: 520 I-----------RTMACGIAGLSVA--ADSLSAIKYAKVKPIRDEDGLAIDFEIEG---- 562
                       R    GI  + +A   DSL AI+ A         G ++D  +E     
Sbjct: 522 FEKGVDVSRGGARYNFTGIQAVGIADVGDSLVAIEGAL------NAGYSMDDIVEACRKN 575

Query: 563 ------------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSN 610
                       + P++GN+D   D     ++E + +++ +   +R          +T+N
Sbjct: 576 FVGYEKLHKLLLQSPKYGNDDDAADKYTKMVLEWYCEEVNRHRNFRGGKFAAGCYPMTTN 635

Query: 611 VVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSI 670
           V +G  T   P GR++G P  PG +P  G D++G  A + S +KL +    +G S T ++
Sbjct: 636 VGFGFFTSALPSGRKSGEPLNPGVSPSTGMDREGVTAVINSASKLSYENLPNGASLTINL 695

Query: 671 VPNALG-KDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQL 729
             + LG K D V +  +   M+          G  H+  N++  ++L  A + PEKY  L
Sbjct: 696 SSDVLGEKGDAVIEALIKSSME---------LGVMHVQFNILKEDLLRKAQQEPEKYRWL 746

Query: 730 TIRVSGYAVRFNSLTKEQQQDVITR 754
            +RV+G++  F  L++  Q++VI R
Sbjct: 747 LVRVAGWSAYFVELSRPVQEEVIRR 771


>UniRef50_C7N778 Pyruvate-formate lyase n=1 Tax=Slackia heliotrinireducens DSM 20476
           RepID=C7N778_SLAHD
          Length = 789

 Score =  136 bits (343), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 136/590 (23%), Positives = 246/590 (41%), Gaps = 79/590 (13%)

Query: 219 RLREEIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFG 278
           RL +   +  RA  ++++MA         P     +A Q  +F ++A        A+ FG
Sbjct: 221 RLADACDDPVRA-AELRQMAENCRVVPENPPQTFWQACQMVWFIHVAFYIEVCTTAIGFG 279

Query: 279 RTSTFLDVYIERDLKAGK-ITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATE 337
           R   ++  + ++D+   K IT  +A E+++ L +K   V  +R   Y   F+G P+W   
Sbjct: 280 RFDQYMWPFYKKDVIDEKNITRDQALEILESLYLKSCEVYEVRDSWYATSFAGYPMWQIL 339

Query: 338 SIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSS 397
            +GG   DG+      S   L     +  + +P M +   +  P    +F  K++ +  +
Sbjct: 340 VVGGQTRDGKDASNDLSMLCLEAADAL-QTTQPVMALRVCDTTPEELIRFGCKMTQEGQA 398

Query: 398 LQYENDDLMRPDFNND------------------DYAIACCVSPMIVGKQMQFF--GARA 437
                     P F ND                  D+ I  C+     G            
Sbjct: 399 ---------NPGFFNDATAMKMALAKGGTLEDARDWTIVGCIQAGPGGGGTDGSPDAGYV 449

Query: 438 NLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITAL-- 495
           N+ K + + ++ GVD      +G ++    GD   +    + ++ F D L KQ + A   
Sbjct: 450 NMGKMIEFVLHDGVDPATGKLMGLRT----GDPREF----KNIEQFKDALKKQIVHAYDQ 501

Query: 496 -----NIIHYMH-DKY-----------SYEASLMALHDRDVIRTMACGIAGLSVAADSLS 538
                N++  +H ++Y             E      H    + T    + G +  ADS++
Sbjct: 502 IRIGYNLMQSIHMNRYPVIFASMVTRGCVENGKSVQHGGANVSTAGMYVTGAANLADSIA 561

Query: 539 AIKYAKVKP---IRDEDGLAIDFEIEGEY----------PQFGNNDPRVDDLAVDLVERF 585
           A++    +      +E   A D   EG+           P++GN+DP VD +  +++   
Sbjct: 562 AVEKCVFEDHDLTMEELIRACDTNFEGQERLRQMLLNKPPKYGNDDPHVDAIYREMMHHI 621

Query: 586 MKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGA 645
            + +Q+    R       + + T N+ +G+ TG  PDGR AG      ++PM GRD  G 
Sbjct: 622 AETVQQWPDARGGHYAFGIDSQTMNLPHGQVTGALPDGRLAGESLCDASSPMMGRDICGP 681

Query: 646 VASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQH 705
            +++ SVA +     ++G  +     P   G   E     + G++  +F +     GG+H
Sbjct: 682 TSTVKSVAAIDQDILQEGALFNLRFDPK--GVQGEKGIDIIEGVVKTFFQN-----GGEH 734

Query: 706 LNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRT 755
           + +NV++ + L+DA ++PE +  L +RV+GY   F  L K+ Q  +I RT
Sbjct: 735 IQINVVDNDTLIDAQKHPELHRGLMVRVAGYMAYFTELDKQAQDTIIRRT 784


>UniRef50_A5N4Z6 Predicted glycyl radical enzyme n=2 Tax=Clostridium kluyveri
           RepID=A5N4Z6_CLOK5
          Length = 800

 Score =  135 bits (340), Expect = 6e-30,   Method: Compositional matrix adjust.
 Identities = 162/681 (23%), Positives = 288/681 (42%), Gaps = 84/681 (12%)

Query: 133 MIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDY 192
           M K +  E+ K  + G++     + L  R  G        Y +G I  D+     Y ID+
Sbjct: 141 MNKLLPDEWHKLFDAGLY----TEFLMQRGPGHTVADGKIYRKGYI--DFINDIQYEIDH 194

Query: 193 LMKDKLAQFTSLQADLENGVNL--EQTIRLREEIAEQHRALG----------QMKEMAAK 240
           L  +      + + +LE G+ L  E  I   E  A+Q RAL           ++ E+A  
Sbjct: 195 LDYNNDVLALNKKEELE-GMKLVCEGMIIFGERYADQARALASVENDPQWKEELLELAEV 253

Query: 241 YGYDISGPATNAQEAIQWTYFGYLAAVKSQNG-AAMSFGRTSTFLDVYIERDLKAGKITE 299
                       ++A+Q  +F ++      N   A S G+    L+ + E+D++ G++T 
Sbjct: 254 CDVVPKHAPRTFRQAVQMYWFTHIGVTTEMNNWDAYSPGKLDQHLEPFYEKDIEEGRLTR 313

Query: 300 QEAQEMVDHLVMKLRM--------VRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVT 351
           +EA E++++L ++           +    +  Y +       +   + G +  DG T V+
Sbjct: 314 EEALEILENLWIQFNNQPTPPKVGITLKESATYTD-------FCNINTGALRPDGTTGVS 366

Query: 352 KNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVS---------IDTSSLQYEN 402
           + S+  L  +  M    +P+  +  S K P  F + A K+S          ++ ++  E 
Sbjct: 367 EVSYLILEVMDEM-KLLQPSSNVQISRKTPEKFLREALKISRKGWGQPAFYNSEAIIQEL 425

Query: 403 DDLMRPDFNNDDYAIAC-CVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGP 461
             L +   +  +  IA  CV     GK+        N+ K     +N G D   K QVG 
Sbjct: 426 LFLGKSIDDARESGIASGCVETGTAGKEAYVLTGYLNIPKIFELVLNRGFDSYTKKQVGL 485

Query: 462 K-SEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVI 520
              +P K    +Y EV +     ++++    I   N+I  M+ +Y     L+++   D I
Sbjct: 486 DLGDPRK--FKSYQEVYDAFYKQLEYVVNVKIAGNNLIERMYMEY-MPVPLLSVITDDCI 542

Query: 521 R-------------TMACGIAGLSVAADSLSAIK---YAKVKPIRDE--DGLAIDFE--- 559
           +             T      G++   DSL +IK   +   K   DE       DF+   
Sbjct: 543 KSGVDYNAGGARYNTSYIQCVGIATITDSLVSIKKNVFEDKKFSMDELLKACKADFKGYD 602

Query: 560 -----IEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYG 614
                +    P++GN+D   DD+  D+ +     I    T + +      L  T +V +G
Sbjct: 603 EIFETVYNHTPKYGNDDDYADDILRDVSQSLQDAIAGRTTPKGSTTVVEFLPTTCHVYFG 662

Query: 615 KKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNA 674
           +    +P+GR AG P   G +P  G D+ G  + + S +K+       G        P+ 
Sbjct: 663 QVMEASPNGRHAGIPLPGGISPEKGADRNGPTSVVKSASKID-QLKTGGALLNQKFTPSV 721

Query: 675 LGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVS 734
           +  ++ +  +N+A L+  YF  +     G H+  NV++R+ LLDA ++PE+Y  L +RV+
Sbjct: 722 VQGEEGI--SNMATLVRSYFSMD-----GHHIQFNVIDRKTLLDAQKHPEEYENLIVRVA 774

Query: 735 GYAVRFNSLTKEQQQDVITRT 755
           GY+  FN+L +  Q ++I RT
Sbjct: 775 GYSDYFNNLDRALQDEIINRT 795


>UniRef50_B8FHW6 Formate C-acetyltransferase n=2 Tax=Desulfobacteraceae
           RepID=B8FHW6_DESAA
          Length = 1000

 Score =  133 bits (335), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 156/658 (23%), Positives = 278/658 (42%), Gaps = 92/658 (13%)

Query: 155 PDILRCRKSGVLTGLPDAYGRGRI----IGDYRRVALYGIDYLMKDKLAQFTSLQADLEN 210
           P IL    SGV+  +     +G++    + D ++  L G+ + M+  +A   +L A    
Sbjct: 372 PKILSLGASGVINEI-----KGKLNQEGLSDRQKGLLEGMIHSMEGMIAYSKNLSAQAAE 426

Query: 211 GVNLEQTIRLREEIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQ 270
               E   + + E+    +A  Q+ E           PA N  EA+   +  ++      
Sbjct: 427 EAAQESDPKRKAELENIAQACAQVVE----------NPARNLDEAVNAVWITWVGMHMEN 476

Query: 271 NGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDEL--- 327
             A +S GR   +L  Y E DL+  KI++ + +E      ++L    F+R  ++  L   
Sbjct: 477 TNAGLSMGRLDQWLQPYYETDLE--KISDGKEREAYIKHAIELVGCLFMRCTDHLPLTPD 534

Query: 328 -----FSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWS-EKLP 381
                F G       ++GG+  +G+  V   ++ FL     +G   +PN+   ++ EK  
Sbjct: 535 LANWYFGGSSSDQAITLGGVTPEGKDAVNDMTYIFLKVTEMLGIR-DPNVNARYNREKNS 593

Query: 382 LNFKKFAAKVSIDTSSLQYENDD------LMRPDFNNDD---YAIACCVSPMIVGKQMQF 432
             + K   +V++ T++    + D      L   D+  +D   ++   CV P + G+ +  
Sbjct: 594 DAYLKRLCEVNLITAATPSLHSDQAVIESLKEFDYAQEDLNNWSATGCVEPTLSGRHIGH 653

Query: 433 FGARA-NLAKTMLYAINGGVDEKLKMQVGPKS-EPIKGDVLNYDEVMERMDHFMDWLAKQ 490
              +  N+   +  A+N G+   +  ++GP++ EP +G    +D+  E       +L  Q
Sbjct: 654 TNFQMMNMVAALEMALNNGLHPLMNWRLGPETGEPAQGAFKTFDDFFEAFTKQFAFLIDQ 713

Query: 491 YITALNIIHYMHDKYSYEASLMALHDRDVIRTMA-------------CGIAGLSVAADSL 537
            +   N++   H        L +L D D I T A                 GL+   DSL
Sbjct: 714 SVEYNNLMGLAHQAIRPTPFLSSLID-DCISTAADVTHGGARYNSSGAACIGLADVTDSL 772

Query: 538 SAIK----------YAKVKPIRDEDGLAIDFE--------IEGEYPQFGNNDPRVDDLAV 579
            AIK          +A +K     + +A +F+        I  + P FG+      ++A 
Sbjct: 773 MAIKKLVYDDKSVSFADLK-----NAVADNFQSEPALHALITHKVPLFGSGSEEAVEMA- 826

Query: 580 DLVERFMKKIQKLHT-YRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMH 638
           + V +F       HT YR    T    +++++V+YG  +G  P G+  G PF PG  P  
Sbjct: 827 NRVAKFAHDHYGTHTNYRGGKYTVGFWSMSNHVIYGTLSGALPSGKLEGKPFTPGLTP-Q 885

Query: 639 GRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKT--NLAGLMDGYFHH 696
                  + ++  VA+L   Y  + +++   IVP   G +D   +T  N+   +  YF  
Sbjct: 886 PIASPNLLDNIRDVARLSPKYITNNLAFNVKIVP---GPNDTHEQTVDNMFSYVKTYFD- 941

Query: 697 EASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITR 754
                GG  + +N +  + L DAM NPE Y  L +R+SGY   F +L ++ Q ++I R
Sbjct: 942 ----LGGMQMQLNAVTSDTLKDAMANPENYRNLLVRISGYNAYFVTLNRDMQLELIER 995


>UniRef50_C0C5J5 Putative uncharacterized protein n=1 Tax=Clostridium hylemonae DSM
           15053 RepID=C0C5J5_9CLOT
          Length = 797

 Score =  132 bits (333), Expect = 4e-29,   Method: Compositional matrix adjust.
 Identities = 146/558 (26%), Positives = 250/558 (44%), Gaps = 65/558 (11%)

Query: 248 PATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVD 307
           PA + QEA+Q  YF +++    QN AA + GR   +L  Y + DL+ G ITE+E  E+++
Sbjct: 253 PARSFQEALQSFYFYHISIFMEQNAAAYNPGRMDQYLYPYYKSDLEEGTITEEEGLELLE 312

Query: 308 HLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNT-----LY 362
            L +K       +        +G P++ T   GG+  +G   V   S+  L       LY
Sbjct: 313 CLWVKFAEPCVFQDATTARYSAGYPMFQTLCCGGIDSEGNDAVNDVSYMMLQATEDVQLY 372

Query: 363 TMGPSPEPNMTILWS-EKLPLNF-KKFAAKVSIDTSSLQYENDDL-MRPDFNND------ 413
                 +PN+T+ +S  K P  F KK A  +S+ T    + NDD+ +R   N        
Sbjct: 373 ------QPNLTVRYSMAKNPNRFLKKIAQVISLGTGFPAFHNDDVGIRMLMNKGIPLKEA 426

Query: 414 -DYAIACCVSPMIVGKQMQFFG-ARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVL 471
            D+  A CV   + G+   +   A  NL   + +A+  GV+ K   +V  ++    GD  
Sbjct: 427 FDWNPAGCVETNLEGRLRHYSAFADINLGGMIEFAMTNGVNRKSGRKVSAET----GDPA 482

Query: 472 NYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASL--MALHDRDVIR-------- 521
           ++ E  +  +H +    K  I A     ++ D    +  +  ++L  R+ +         
Sbjct: 483 SFTEYGD-FEHAVKEQLKFSIQACVKGSHVIDDICMDRVVPALSLSFRECVEQAKDYAWG 541

Query: 522 ---------TMACGIAGLSVAADSLSAIKYAKVKPIRDED---GLAIDFE-------IEG 562
                     +  G+A L  + +++  + Y K K +  ED    L  DFE       +  
Sbjct: 542 GAKYNAGNGIILIGVADLINSMEAVKELVYEK-KLVSMEDMVNALNADFEGYEEIRELCQ 600

Query: 563 EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPD 622
           +  ++GN+D  V+++A  ++     +I++ H+    + T  +L ++ N  +G+  G  P 
Sbjct: 601 KCRKYGNDDEEVNEIASHMLTFIADEIEQYHSKFGQM-TPGILPVSGNTPFGQDVGALPS 659

Query: 623 GRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVR 682
           GR+A  P   G +P  G D  G  A L S A +P A    G      + P+ +  ++ ++
Sbjct: 660 GRKAWTPLADGISPNGGTDVSGPAAVLKSAASIPHARYVQGTLLNMKLEPDMVKTENGIQ 719

Query: 683 KTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNS 742
           +  L  L+           G  H+  NV++RE LL A + PE Y  L +RV+GY   F  
Sbjct: 720 Q--LMALLKSL-----CTLGVYHVQFNVIDRETLLAAQKKPEDYRGLLVRVAGYTAYFTE 772

Query: 743 LTKEQQQDVITRTFTQSM 760
           L K+ Q ++I+RT   S 
Sbjct: 773 LGKDVQDEIISRTAQSSF 790


>UniRef50_UPI00016BFDA6 pyruvate formate-lyase n=1 Tax=Epulopiscium sp. 'N.t. morphotype B'
           RepID=UPI00016BFDA6
          Length = 766

 Score =  129 bits (325), Expect = 3e-28,   Method: Compositional matrix adjust.
 Identities = 167/725 (23%), Positives = 287/725 (39%), Gaps = 123/725 (16%)

Query: 119 IEGSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGR-GR 177
           +E   K Y+R  D  ++  F        + V   YT   L+CR        P  +   G 
Sbjct: 79  VEEILKVYHRWWDMSVEDRF--------KKVAFYYTNGWLKCR--------PYWFASFGH 122

Query: 178 IIGDYRRVALYGIDYLMKDKLAQFTSL----QADLENGV--NLEQTIRLREEIAEQHRAL 231
           +  DY  +   G D ++K    + T      Q +  NG+  +++      E  A    A 
Sbjct: 123 LGIDYEDLVFNGYDSIIKRAQTRLTKSCNEKQQEFLNGIIISIQALSNFYERYATAAVAA 182

Query: 232 GQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERD 291
           G++ ++A         PA   ++A+Q  +   L   K      ++F R   +L    ++D
Sbjct: 183 GKI-DLADDLKTIAHQPAKTFKQALQHIWLNTLVLQKVSGCGVLNFSRLDKYLQPLYDQD 241

Query: 292 LKAGKITEQEAQEMVDHLVMKLRMV---------RFLRTPEYDELFSGDPIWATESIGGM 342
           +KAG +T +EA  +V+    +   +             T +  EL   DP + T  +GG+
Sbjct: 242 IKAGILTREEALNLVEEFYFRNNEMMAQTDHMSEETTGTKDTLELAFDDPNYLT--LGGI 299

Query: 343 GLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSSLQYEN 402
             DG + V + S+  L     M     P + + + E +  +F K  AK   + +++   N
Sbjct: 300 NADGTSAVCELSYIMLEAANEMRLR-NPFIVVRYHEGIAEDFWKLCAKAMRNNATVVVYN 358

Query: 403 DDLMRPDFNND--------DYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGG---- 450
           D+ M P             DY    C  P I   +        N+AK +  A++ G    
Sbjct: 359 DETMIPALKYHNISAPEVYDYGFWGCNDPNIAAYEGGLRQLWMNMAKPLELALHQGDYPL 418

Query: 451 ----------------VDEKLKMQVGP----KSEPIKGDVLNYDEVME----RMDHFM-- 484
                            D  + + +GP    K++P   ++ + +E ++    + DH +  
Sbjct: 419 EPKKEEDVAKECAWSIEDRMMGIMIGPYYGIKTKP-ANEINSMEEFLKIFEIQFDHLISE 477

Query: 485 -------DWLAKQYITALNI-IHYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVAADS 536
                  D++ +Q+ T   + I     K + E ++           +     GL+   ++
Sbjct: 478 FRKGFEADFIIEQHETVGKMRIEDCFLKGTIENAVTWTEGGTKYHKIVAQGCGLATVINA 537

Query: 537 LSAIKYAKVKPIRDEDGLAID-----------------FEIEGEYPQFGNNDPRVDDLAV 579
           L  I+    K + DE  L ++                  + + +YP+FGN+   VD  A 
Sbjct: 538 LYIIE----KVVFDEKLLTLEELATMMRNNYEGNEHWRLKFKNKYPKFGNDIDEVDKYAQ 593

Query: 580 DLVERFMKKIQK------LHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPG 633
            + + FM+ I K      L+ +     T    TI      G+  G TPDGR A  P    
Sbjct: 594 IITDIFMRIIAKHNGPEYLYQFWPTYSTDRAFTIM-----GEHVGATPDGRLAREPISEN 648

Query: 634 ANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGY 693
            +P  G D +G  A L S++K+PF     G      + P     D  +    +A L+  Y
Sbjct: 649 QSPADGSDLEGVTAMLNSLSKVPFNRITGG-PLNLRLHPTVAAGDKGI--DTVAALLKTY 705

Query: 694 FHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVIT 753
                  +GG  L +NV++ E L  A ENP+KY  L +RV+GY+  F  + K+ Q ++I 
Sbjct: 706 MQ-----KGGMQLQLNVIDAETLKLAQENPDKYRSLCVRVTGYSAFFVEMGKKAQDELIH 760

Query: 754 RTFTQ 758
           RT  Q
Sbjct: 761 RTQHQ 765


>UniRef50_A6TPN1 Formate C-acetyltransferase n=3 Tax=Clostridiaceae
           RepID=A6TPN1_ALKMQ
          Length = 789

 Score =  127 bits (320), Expect = 1e-27,   Method: Compositional matrix adjust.
 Identities = 135/572 (23%), Positives = 239/572 (41%), Gaps = 71/572 (12%)

Query: 232 GQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERD 291
           G++ ++A   G     P     EAIQ+ +F  +  + S+N  A++ GR   F+  Y + D
Sbjct: 236 GELLKIADICGRIPENPPDTFYEAIQFVWFTQVGGIISENPLALNIGRFDQFMYPYYKSD 295

Query: 292 LKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVT 351
           +  G IT+ EAQE+++ L +KL    +  +    E F+G   +   ++GG   +G+    
Sbjct: 296 VDKGIITKDEAQELIEALWIKLSEWVWTISANTAEFFAGYNQFQNLTVGGKTREGKDATN 355

Query: 352 KNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNF-----------KKFAAKVSIDTSSLQ- 399
             S+  L     +  + +P +++   +  P +F             F A +  DT+  Q 
Sbjct: 356 DLSYMCLKATERV-KTHQPGLSVRVHQDSPRSFLDAVTHLVSKGTGFPA-IHNDTAGYQM 413

Query: 400 -----YENDDLMRPDFNNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEK 454
                YE +D    D+NN       CV P              N    + +A+N G    
Sbjct: 414 LINAGYEPEDAR--DWNN-----CGCVVPHFRKTGEWTSAVNINFTAALEFALNQGESRI 466

Query: 455 LKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMAL 514
              ++G   E       +Y+EV +      D L +  I A  +   +H +      L + 
Sbjct: 467 TGEKIG-MDEDKPTTFQSYEEVEKAFYKQFDNLIEHSIIATLLAQKLHKEMVPRPFLSSC 525

Query: 515 HDRDVIR--------------TMACGIAGLSVAADSLSAIKYAKVKPIRDEDGL------ 554
            +  +I+               +  GI GL+V ++SL+ IK      +  ED +      
Sbjct: 526 IEECMIKGKDLVDAGAKYNLGPVLTGI-GLAVTSNSLAVIK-----KLVFEDKMTTMETL 579

Query: 555 --AIDFEIEG---------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQS 603
             A+D   EG           P++GNN   VDD+A+ +   + K+  K           +
Sbjct: 580 IKALDANWEGYEKLRQLAVSVPKYGNNVDYVDDIAIKIANYYYKQGHKYKDINGNNFNTA 639

Query: 604 VLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDG 663
            + I++ +  GK  G TP GR+A  P   G +P  G D    + ++ S AKL       G
Sbjct: 640 FMGISNYLPTGKVVGATPCGRKAKEPLSEGVSPFAGSDTSTPLEAMRSAAKLNQDVHSGG 699

Query: 664 ISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENP 723
                 +  + +  + +  ++NL  ++  +F       G  H+  N ++ + L  A  NP
Sbjct: 700 TLLNLRLNEDLV--NTKRGQSNLGFMIQSFFAL-----GAFHVQFNTISTDTLRKAQNNP 752

Query: 724 EKYPQLTIRVSGYAVRFNSLTKEQQQDVITRT 755
           + Y  L +RV+GY+ +F +L+K  Q+ +I RT
Sbjct: 753 QDYKDLLVRVAGYSTQFVNLSKSMQEAIIART 784


>UniRef50_C0W9F6 Formate C-acetyltransferase n=1 Tax=Acidaminococcus sp. D21
           RepID=C0W9F6_9FIRM
          Length = 805

 Score =  126 bits (317), Expect = 3e-27,   Method: Compositional matrix adjust.
 Identities = 169/711 (23%), Positives = 279/711 (39%), Gaps = 106/711 (14%)

Query: 128 RELDPMI-----KKIFTEYRKTH--NQGVFDVYT----PDILRCRKSG-VLTGLPDAYGR 175
           R  DP       KK++TE  + +  N+ VFD +      D  R R +G +        G 
Sbjct: 108 RPFDPFYLSEEGKKVYTEKVQNYWKNKCVFDRWNLMLPEDAKRLRANGAIFIDRKAVRGY 167

Query: 176 GRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLENGVNLEQTIRLREEIAEQ-------H 228
           G     + R+   G+  + K+       L  D  N  +LE++   + EI          H
Sbjct: 168 GENTPGWMRILTKGLAAIRKEAEDALAKL--DDANPGDLEKSFFYKAEIKAADAVILLAH 225

Query: 229 RALGQMKEMAAKYGYDISG----------------PATNAQEAIQWTYFGYLAAVKSQNG 272
           R     ++MAA+    +                  PA    EA Q       A    QN 
Sbjct: 226 RHADLAEKMAAECDDPVRKAELLKIAEVTRHVPEYPARTFYEACQSIISYEYACFMEQNA 285

Query: 273 AAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDP 332
           ++ + GR   +L  Y ++D +AG +T+ +AQE++D L +K+  +   +     +  +G  
Sbjct: 286 SSYNLGRLDQYLYPYYKKDKEAGILTDDDAQELLDCLWIKVAEMSLFQDEVTAQYAAGYC 345

Query: 333 IWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWS-EKLPLNFKKFA--- 388
           I    S GG+   G     + S+  +     +    EPNM + +S  K P +  + A   
Sbjct: 346 ITVQTSCGGIDQYGNDASNELSYMMIQATEDV-RFKEPNMAMTYSISKNPDSLLRKAIES 404

Query: 389 --------AKVSIDTSSLQYENDDL-MRPDFNNDDYAIACCVSPMIVGKQMQFFG-ARAN 438
                   A  S D      +N  + +R  +N   +    CV   + GK  Q+   A  N
Sbjct: 405 IGMGLTMPAIYSNDVGIQMLQNKGIPLREAWN---WNPCGCVETNLSGKMKQYTDIADIN 461

Query: 439 LAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNY---DEVMERMDHFMDWLAKQYITAL 495
           +   + +A+N G       QV   +    GD  N+   D+    +   +D+     ++  
Sbjct: 462 MGAMVEFALNDGKSRITGEQVSIHT----GDPRNFKTFDDFFAAVKKHIDYAVDVIVSCN 517

Query: 496 NIIHYMHDKY--------SYEASLMALHDRD----VIRTMACGI--AGLSVAADSLSAIK 541
            ++ Y+   Y        SYE  +    D             G+   G +   +S++ +K
Sbjct: 518 QLLDYLSMNYRPVPTLSLSYEHCMEVGKDYSQPGGAQYNAGGGVITVGQADIINSIADVK 577

Query: 542 YAKVKPIRDEDGL-------AIDFEIEG---------EYPQFGNNDPRVDDLAVDLVERF 585
           Y     + DE  +       A+D   EG         E P++GN+DPR D    ++    
Sbjct: 578 YL----VFDEKKISMDTLIKALDANFEGYEDIQKLCLEAPKYGNDDPRADFCVGEIFNHV 633

Query: 586 MKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGA 645
             + +K  T    + T  +L ++ N   G+  G  P GR+A  P   G     G D  G 
Sbjct: 634 ADQFEKYDTVFGKM-TLGMLPVSGNTPIGQWVGALPSGRKATTPLTDGIGATGGTDVNGP 692

Query: 646 VASLTSVAKLPFAYAKDGISYTFSIVPNAL-GKDDEVRKTNLAGLMDGYFHHEASIEGGQ 704
            A L SV+ LP A    G        P+ + G++      N+   M        S+ G  
Sbjct: 693 TALLKSVSHLPHARFTQGTQLNMKFEPDLIKGENGMTHAMNMVKTM--------SVLGVY 744

Query: 705 HLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRT 755
           H  +N ++RE L+DA ++P  +  L IRV+GY   F  L KE Q ++I RT
Sbjct: 745 HAQINCVDRETLIDAQKHPNDHRDLLIRVAGYTAFFVELGKETQDEIIGRT 795


>UniRef50_A9KN53 Pyruvate formate-lyase n=21 Tax=Bacteria RepID=A9KN53_CLOPH
          Length = 867

 Score =  125 bits (314), Expect = 6e-27,   Method: Compositional matrix adjust.
 Identities = 67/191 (35%), Positives = 103/191 (53%), Gaps = 7/191 (3%)

Query: 565 PQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGR 624
           P++GN+   +D+ A ++   + K +QK    R  +    +  +++NV  G++TG TPDGR
Sbjct: 680 PKYGNDILEIDEFAREIAYTYTKPLQKYKNPRGGVFQAGLYPVSANVPLGEQTGATPDGR 739

Query: 625 RAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKT 684
            A  P   G  P  GRD KG  A+  SVA+L    A +G  Y     P+AL     + K 
Sbjct: 740 LANTPIADGVGPAPGRDTKGPTAAANSVARLDHMDATNGTLYNQKFHPSALQGRGGLEK- 798

Query: 685 NLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLT 744
               L+  +F  +     G H+  NV++RE LLDA ++PE Y  L +RV+GY+  F +L+
Sbjct: 799 -FVALIRAFFDQK-----GMHVQFNVVSRETLLDAQKHPENYKHLVVRVAGYSALFTTLS 852

Query: 745 KEQQQDVITRT 755
           +  Q D+I RT
Sbjct: 853 RSLQDDIINRT 863



 Score = 73.2 bits (178), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 91/331 (27%), Positives = 143/331 (43%), Gaps = 53/331 (16%)

Query: 248 PATNAQ---EAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQE 304
           PA  A    EA Q  +F  L      +G ++S GR   +L  Y + D +AG+IT ++AQE
Sbjct: 255 PAKGANTFYEACQAFWFVQLLLQIEASGHSISPGRFDQYLYSYYKADREAGRITGEQAQE 314

Query: 305 MVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLN-TLYT 363
           ++D + +KL  +   R     E F+G  ++    +GG   +GR    + SF  L  +++T
Sbjct: 315 IIDCIFVKLNDINKCRDAASAEGFAGYGMFQNMIVGGQDSNGRDATNELSFMILEASIHT 374

Query: 364 MGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSSL-QYENDDLMRPDFNND--------D 414
           M   P+P+++I      P +    AA+V+     L  Y ND+++ P   N         +
Sbjct: 375 M--LPQPSLSIRVWNGSPHDLLIKAAEVTRTGIGLPAYYNDEVIIPAMMNKGATLEEARN 432

Query: 415 YAIACCVSPMIVGKQMQFF-GARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLN- 472
           Y I  CV P + GK   +   A  N+ + +    + G  E  K+   P      G V N 
Sbjct: 433 YNIIGCVEPQVPGKTDGWHDAAFFNMCRPLEMVFSSGY-ENGKLVGAP-----TGSVENF 486

Query: 473 ------YDEVMERMDHFMDWLAKQYITALNIIHYMHDKYS---YEASLMALHDRDVIRTM 523
                 YD    +M++F+  L    + A N I   H K     +E+S++     D I   
Sbjct: 487 TTFEAFYDAYKTQMEYFISLL----VNADNSIDIAHAKLCPLPFESSMV----EDCIGRG 538

Query: 524 AC-----------GIAGLSVA--ADSLSAIK 541
            C           G  G  +A   DSL AIK
Sbjct: 539 LCVQEGGAKYNFTGPQGFGIANMTDSLYAIK 569


>UniRef50_B1EF41 Keto-acid formate acetyltransferase (Keto-acid formate-lyase) n=3
          Tax=Enterobacteriaceae RepID=B1EF41_9ESCH
          Length = 96

 Score =  125 bits (314), Expect = 6e-27,   Method: Compositional matrix adjust.
 Identities = 55/78 (70%), Positives = 67/78 (85%)

Query: 9  ATAWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLWDKVMEGVKLENRT 68
          A AW GF   DW++E+NVRDFIQ NYTPYEGDESFLA AT ATT LW+KVMEG+++EN T
Sbjct: 13 ANAWLGFKGTDWKDEINVRDFIQHNYTPYEGDESFLAEATPATTALWEKVMEGIRIENAT 72

Query: 69 HAPVDFDTAVASTITSHD 86
          HAP+DFDT +A+TIT+H+
Sbjct: 73 HAPLDFDTNIATTITAHE 90


>UniRef50_Q1A666 Glycerol dehydratase n=8 Tax=Clostridiales RepID=Q1A666_9FIRM
          Length = 843

 Score =  125 bits (313), Expect = 8e-27,   Method: Compositional matrix adjust.
 Identities = 68/193 (35%), Positives = 102/193 (52%), Gaps = 7/193 (3%)

Query: 563 EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPD 622
           E P++GN+   VD+LA +    + + ++     R  +    +  +++NV  G +TG TPD
Sbjct: 652 ELPKYGNDIDEVDELAREAAYFYTRPLETFKNPRGGMYQAGLYPVSANVPLGAQTGATPD 711

Query: 623 GRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVR 682
           GR A  P   G  P  G D  G  AS  SVAKL  A A +G  +   + P A+  +  + 
Sbjct: 712 GRLAHTPVADGVGPTSGFDISGPTASCNSVAKLDHAIASNGTLFNMKMHPTAMAGEKGLE 771

Query: 683 KTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNS 742
             +   L+ GYF  +     G H+  NV++R  LLDA  +PEKY  L +RV+GY+  F +
Sbjct: 772 --SFISLIRGYFDQQ-----GMHMQFNVVDRATLLDAQAHPEKYSGLIVRVAGYSALFTT 824

Query: 743 LTKEQQQDVITRT 755
           L+K  Q D+I RT
Sbjct: 825 LSKSLQDDIIKRT 837


>UniRef50_A8MJE8 Formate C-acetyltransferase n=57 Tax=Bacteria RepID=A8MJE8_ALKOO
          Length = 849

 Score =  123 bits (308), Expect = 3e-26,   Method: Compositional matrix adjust.
 Identities = 139/559 (24%), Positives = 244/559 (43%), Gaps = 87/559 (15%)

Query: 254 EAIQ--WTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVM 311
           EAIQ  WT    L   ++Q G  MS GR   ++  + + D+++G++TE EA E+   +++
Sbjct: 318 EAIQAVWTIESLLVVEENQTG--MSIGRVDQYMYPFYKADIESGRMTEFEAFELAGAMLI 375

Query: 312 KLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPN 371
           K+  + ++ +    + F+G   +    +GG+  +G       ++  ++ +  +    +P+
Sbjct: 376 KMSEMMWVTSEGGSKFFAGYQPFVNMCVGGVTREGLDATNDLTYLLMDAVRHVKIY-QPS 434

Query: 372 MTILWSEKLPLNFKKFAAK-VSIDTSSLQYEN---DDLMRPDF--------NNDDYAIAC 419
           +      K P   KK+  K V +  S + +     DD+             +  DY +  
Sbjct: 435 LATRIHSKSP---KKYLKKIVDVVRSGMGFPACHFDDVHIKMMLAKGVSIEDARDYCLMG 491

Query: 420 CVSPMIVGKQMQFFG-ARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVME 478
           CV P   G+  Q+   A       +   +N GV     +  G +  P  GD+  Y    +
Sbjct: 492 CVEPQKSGRLYQWTSTAYTQWPIAIELVLNNGV----PLWYGKQVTPNMGDINQYKTYEQ 547

Query: 479 RMDHFMDWLAKQYITALN-----IIHYMHDKYS--------YEASLMALHDRD---VIRT 522
                 + +  QYIT L+     I   +H   +        YE  + +  D      +  
Sbjct: 548 FEAAVKEQI--QYITKLSNIATVISQRVHRDLAPKPLMSIMYEGCMESGKDVSAGGAMYN 605

Query: 523 MACGI--AGLSVAADSLSAIKY-----AKVKPIRDEDGLAIDF----EIEGEY---PQFG 568
              G+  +GL+   DS++AIK       K    +  + L  DF    +++ +    P++G
Sbjct: 606 FGPGVVWSGLATYVDSMAAIKKLVFDDKKYTLQQLNEALKADFVGYDQVKSDCLKAPKYG 665

Query: 569 NNDPRVDDLAVDLV---ERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRR 625
           N+D  VD +A DLV   E+  +K + LH+    I     L+I++N  +G+ TG T +GR 
Sbjct: 666 NDDDYVDLIAADLVNFTEKEHRKYRTLHS----IMCHGTLSISNNTPFGQLTGATANGRG 721

Query: 626 AGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTN 685
           A  P   G +P  G D KG  A + SV+K+       G+ + F ++              
Sbjct: 722 AWTPLSDGISPTQGADFKGPTAIIKSVSKMACDNMNLGMVHNFKLI-------------- 767

Query: 686 LAGLMDGYFHHEASIE--------GGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYA 737
            AGL+D     E  I         G   +  N ++   LL+A ++PEKY  L +RV+GY+
Sbjct: 768 -AGLLDTPEGEEGIITLLRTANNIGIGEMQFNYLDNNTLLEAQKHPEKYRDLIVRVAGYS 826

Query: 738 VRFNSLTKEQQQDVITRTF 756
             F  L K+ Q ++I+RT 
Sbjct: 827 AFFVELCKDVQDEIISRTM 845


>UniRef50_B0MIH0 Putative uncharacterized protein n=1 Tax=Anaerostipes caccae DSM
           14662 RepID=B0MIH0_9FIRM
          Length = 803

 Score =  122 bits (307), Expect = 4e-26,   Method: Compositional matrix adjust.
 Identities = 142/563 (25%), Positives = 244/563 (43%), Gaps = 65/563 (11%)

Query: 226 EQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLD 285
           E+ R L +M ++  K       PA +  EA+Q T+  ++ A   Q G+A+SFGR   +L 
Sbjct: 270 ERSRELKRMADICRKIS---EKPAKSFYEAVQLTWMLHIIA-NIQGGSALSFGRLDQYLY 325

Query: 286 VYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLD 345
            Y ++D + G+IT  EA+E+V  L +K+   + +RT +            + ++GG+  D
Sbjct: 326 PYFKKDTEEGRITYSEAKELVGCLWLKVNEPK-MRTVQ------------SVTLGGITPD 372

Query: 346 GRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLP-LNFKKFAAKVSIDTSSLQYENDD 404
           G+    + +   L T    G  P PN+ +  +   P   +++    +          ND+
Sbjct: 373 GKDAANELTRICLQTAKDAG-MPYPNVGLRVNRLNPDWIYEEALETIKAGCGQPMLLNDE 431

Query: 405 --------LMRPDFNNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLK 456
                   L  P+   +DY    CV  MI GKQ  + G    +A  +L        E++ 
Sbjct: 432 IWITNMKKLGYPEDQANDYYNMGCVEIMIPGKQPNW-GVTEAIAFPVLI-------EEVM 483

Query: 457 MQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITA-LNIIHYMHDKYSYEASLMAL- 514
            + G     I+      D  ++ MD  ++   ++ +    N+    +D +S       L 
Sbjct: 484 RKWGAGEIKIRSFDEFMDAYLQEMDIAIEADRQEALQKKANMTERCYDPFSSVLIDGCLE 543

Query: 515 HDRDVIRTMA-CGIA------GLSVAADSLSAIKY-----AKVKPIRDEDGLAIDFE--- 559
           H +D+++  + C +       G+  AADSL A+K       KV   + +D L  DFE   
Sbjct: 544 HGKDMLQGGSECPVHWSVYAYGIGTAADSLCAVKKFVFDDQKVTLEQMKDALEADFEGYE 603

Query: 560 -----IEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKL-HTYRDAIPTQSVLTITSNVVY 613
                ++   P +GN    VD +A  ++  F K + +L H         ++     ++ +
Sbjct: 604 ELRAMLDRMTPAYGNGLEEVDSIADKVLTHFSKSVFELNHNSEKDKYVSTLFGYFFHIYH 663

Query: 614 GKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPN 673
           G+  G TP+GR  G PF     P  G+D KG    L SV +L   Y   G +  + + P 
Sbjct: 664 GEIVGATPNGRHKGEPFSDSMGPGQGKDVKGPTRLLHSVIRLNDDYITGGYALNYKLNPA 723

Query: 674 ALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRV 733
            L  ++E  +     L+  Y  +      G  + V   N + + DA  +PEK+  L +RV
Sbjct: 724 FL--NEEKGRQAAISLLKTYIENR-----GPQIQVYTTNLDDIKDAQVHPEKHRDLIVRV 776

Query: 734 SGYAVRFNSLTKEQQQDVITRTF 756
            GY   F +L +  Q ++I RT 
Sbjct: 777 GGYCEFFVNLDRVLQNEIIARTM 799


>UniRef50_A8ZW07 Formate C-acetyltransferase n=2 Tax=Proteobacteria
           RepID=A8ZW07_DESOH
          Length = 782

 Score =  122 bits (306), Expect = 5e-26,   Method: Compositional matrix adjust.
 Identities = 128/549 (23%), Positives = 227/549 (41%), Gaps = 61/549 (11%)

Query: 254 EAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKL 313
           EA+Q     +++  +   G ++  GR    L  Y ++DL  G++T  +A+E++    +KL
Sbjct: 252 EAVQAMLLTHISLFQESLGESLCVGRMDQILWPYYQKDLSEGRLTRDQAKEILGAFCVKL 311

Query: 314 RMVRFLRTPEYDELFS----GDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPE 369
                   P Y E+ +    G   +   + GGM  +G     + S+  L  +  +    +
Sbjct: 312 SET----VPAYPEILAKTLGGLTSYQVVTTGGMDKNGEDATNELSYILLELMDELRMR-Q 366

Query: 370 PNMTILWSEKLPLNFKKFAAKVSIDTSSL-QYENDDLMRPDFNNDDYAIA--------CC 420
           PN  +   +  P  F     +V+    S     ND+ +        Y +A         C
Sbjct: 367 PNSHVRIHKNTPKAFYDKVVEVTTGKGSAPALYNDETIIATMQKAGYTLADARNYVAIGC 426

Query: 421 VSPMIVGKQM-QFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMER 479
           V P   GK +     A  N+   +  A+N G     + + G K+      VL    + + 
Sbjct: 427 VEPTSQGKTLGSTDAAIINMPLALELALNEGRRFGARRRTGAKTMA----VLQMRTMADV 482

Query: 480 MDHFMDWLAKQYITALNIIHYMHDKYS--YEASLMALHDRDVIRTMACGIAGLSVAADSL 537
            D +   L  Q     N +  +   ++  +   L ++     +    C  +G +V   + 
Sbjct: 483 TDAYRTQLRHQLGRLKNDLQAIEKAHAAFHPTPLTSMLIDGCLEKGKCSTSGGAVY--NF 540

Query: 538 SAIKYAKVKPIRD----------ED---GLA--IDFEIEG-----------EYPQFGNND 571
           S I+   V  + D          ED   GLA  +D    G              +FGN+ 
Sbjct: 541 SGIQGVGVSTVGDSLYAVEKMVFEDRAMGLAELVDHLKSGLSNEAVRTRLRRLEKFGNDH 600

Query: 572 PRVDDLAVDLVERFMKKIQKL-HTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPF 630
              D     +++ +   + ++  T R       + + T+++ +    G  P+GRR G PF
Sbjct: 601 AEADRWTRFVMDDYADAMAEMGQTTRGGRYNAGLYSNTTHIHFANFVGALPNGRRQGEPF 660

Query: 631 GPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLM 690
             G  P +G D++G  A + S+ +L F    +GI+  F+I  NAL   D+  K  L  + 
Sbjct: 661 ASGIAPENGMDRRGPTALVNSMNRLDFTRMANGIN--FNIKFNALNMKDDAGKNALGSIF 718

Query: 691 DGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQD 750
             YF       GG  +  N+++ EML+ A +NP  +P L +RVSGY+  FN L+ E + +
Sbjct: 719 RVYFD-----RGGMQVQANMLDPEMLMAARDNPSLHPHLLVRVSGYSAYFNDLSPEMKDE 773

Query: 751 VITRTFTQS 759
           +I R+F  +
Sbjct: 774 IIARSFVAA 782


>UniRef50_A5CZF4 Pyruvate-formate lyase n=1 Tax=Pelotomaculum thermopropionicum SI
           RepID=A5CZF4_PELTS
          Length = 835

 Score =  115 bits (289), Expect = 5e-24,   Method: Compositional matrix adjust.
 Identities = 132/553 (23%), Positives = 235/553 (42%), Gaps = 57/553 (10%)

Query: 251 NAQEAIQWTYFGYLAAVK-SQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHL 309
           N  EA+Q   F +LAA K S     +  GR    L  Y ++D+  G +T Q+A E++  L
Sbjct: 294 NFWEAVQSLRFLHLAAWKESTERPEVGVGRIDQILYPYYKKDIDEGTLTRQDAAELLGAL 353

Query: 310 VMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPE 369
            +K+R    L T + +   +   +    ++GG    G  L+ + S+  L  +     S E
Sbjct: 354 WLKIRETENLVTIKREHRAAPGTLLPNVTLGGRNELGEDLINEVSWIVLEVMRQTKLS-E 412

Query: 370 PNMTILWSEKLPLNFKKFAAKVSID--TSSLQYENDDLMR--------PDFNNDDYAIAC 419
           P + I + + +  +F   A + + D    +  + ND+L          P  +  ++  + 
Sbjct: 413 PAIYIRYHDGIDEDFMIHALECNRDFGGGNPAFLNDELGTQRYLARGVPLKDAVNWNASG 472

Query: 420 CVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNY------ 473
           C+   +   + Q      N AK     +  G D +   Q+G K+    GDV  +      
Sbjct: 473 CLGYHLDCGEHQGGFFSLNHAKIFEITLYNGFDPRTGKQLGLKT----GDVTKFTSLQQF 528

Query: 474 -DEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLM-------ALHDRD------V 519
            D   +++D+F + L K Y     +   +       A+++        L  R+       
Sbjct: 529 IDAFYKQVDYFCERLRKHYFIWWCVEQEISPMSGLRAAMLYEDCIPAGLCSREGGARYPS 588

Query: 520 IRTMACGIAGLSVAADSLSAIKY-----AKVKPIRDEDGLAIDFEIEGEYPQFGNNDPRV 574
           +R+   G  G++  ADSL+AI++      +V      D +  ++E + E  Q   N P+ 
Sbjct: 589 LRSSWIGDRGITDIADSLAAIQHLVFDTKQVTMAELLDAMRNNWEGKEELRQMCLNAPKY 648

Query: 575 ---DDLAVDLVERFMKKIQKLHTYR-DAIPTQSVLTI----TSNVVYGKKTGNTPDGRRA 626
              +DL  +L    M   Q++   R D I  +  +        ++  G   G  P+GR A
Sbjct: 649 GNDEDLPDNLFGELMFGTQRIMQSRPDPITGEKPILFKGAAAGHITQGASVGALPNGRFA 708

Query: 627 GAPFGPGANP-MHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTN 685
             P    A+  M G D  G  A + S  K  +A+   G ++        L   ++++K  
Sbjct: 709 YKPLNDAASSAMPGMDVNGPTAVINSATKGNYAFEYVGFTHNMKFSKQTLNTPEKLKK-- 766

Query: 686 LAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTK 745
           L  ++  +F       GG H+  N+ + E LLDA ++PE+Y  L +RV GY+  F  L  
Sbjct: 767 LINILKTFFKR-----GGWHIQFNIHSVEELLDAQKHPERYRNLLVRVGGYSAYFIDLPP 821

Query: 746 EQQQDVITRTFTQ 758
           E Q++++ RT  +
Sbjct: 822 ELQEEIVQRTMHE 834


>UniRef50_Q30WU7 Formate C-acetyltransferase n=1 Tax=Desulfovibrio desulfuricans
           subsp. desulfuricans str. G20 RepID=Q30WU7_DESDG
          Length = 811

 Score =  115 bits (288), Expect = 7e-24,   Method: Compositional matrix adjust.
 Identities = 149/633 (23%), Positives = 247/633 (39%), Gaps = 96/633 (15%)

Query: 181 DYRR---------VALYGIDYL--MKDKLAQFTSLQADLENGVNLEQTIRLREEIAEQHR 229
           DYRR         + L GIDY    +D   +  + + D      LE+  R+   + E   
Sbjct: 213 DYRRHEFWLGLKEMLLGGIDYAHRYRDLATELAAKETDPVRKAELEEMARVCNRVPEH-- 270

Query: 230 ALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIE 289
                             PA   QEA+Q   FG L          M +GR    +    +
Sbjct: 271 ------------------PAETFQEALQSLVFGLLMVFYDTRTFGMGYGRIDQIMYPQYK 312

Query: 290 RDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLD-GRT 348
            D+ +GKI ++   ++ +   +K+   R           S +  +    I G+    GR 
Sbjct: 313 SDIASGKIDDEYVVQLFECFRVKIMGKRQFWPDVMTPNLSSESHFHNCVICGVDPKTGRD 372

Query: 349 LVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFA---AKVSI-------DTSSL 398
              + SF FL     +  +  P +++ W  ++   F K A    K+ +       D  S+
Sbjct: 373 ATNELSFAFLEAAERV-RTTHPTISVRWHTQIDPKFMKRALETVKLGMGFPAFFNDEPSI 431

Query: 399 QYENDDLMRPDFNNDD---YAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKL 455
           QY    L+   +  ++   YA+  C    + GK    +    +  + +   +  G D   
Sbjct: 432 QY----LLARGYTMEEARNYALGGCTLHTVPGKTSSIWPLVTSYGRILELTMYNGWDFIS 487

Query: 456 KMQVGPKSEPIKGD---VLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLM 512
             Q+GPK+    GD   + +Y+E +      +++ A     +       H     +  + 
Sbjct: 488 NSQLGPKT----GDFTQMTSYEEFVAAYKAMIEYWANVSTKSGRAAKLQHGDTFPDIMMS 543

Query: 513 ALHDRDVIRTMACGIAGLSVAADSLSAIKYAKVKPIRDE--------------------- 551
           A  D  + R   C + G +  ADS   I    V+ + +E                     
Sbjct: 544 AFTDDCIGRGKVCSLGG-AEHADSCMYIVPVAVQDVANELYVLKHGVFGENPICTPQEML 602

Query: 552 DGLAIDFEIEGEY-------PQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQ-S 603
           D +  ++E   E        P+FGN+ P VD L  D V  ++K+I       D    + S
Sbjct: 603 DAMRANWEGHEELRAKCMAMPKFGNDIPEVDQLLTD-VYNWIKEIWHAQPATDGGRYEVS 661

Query: 604 VLTITSNVVYGKKTGNTPDGRRAGAPFGPGA-NPMHGRDQKGAVASLTSVAKLPFAYAKD 662
             +I  +   G KTG  P GR+AG  F  GA +P+ G D  G  A + S   +   +   
Sbjct: 662 PHSIGFHGGTGAKTGALPCGRKAGTSFSDGAVSPVQGTDVNGPSAVIKSAGSID-QHDLY 720

Query: 663 GISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMEN 722
           G+ +     P+ +    E    NLA L+  YF    S   G+H+  NV+NR+ L+ A + 
Sbjct: 721 GVLFNMRFSPSNI--RGEKGTANLASLIKTYF----SDYKGKHIQFNVLNRDDLIAAKKE 774

Query: 723 PEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRT 755
           PEKY  L +RV+GY+  +  L    Q ++I RT
Sbjct: 775 PEKYKDLMVRVAGYSAYWTDLPANIQDELIART 807


>UniRef50_B8J0R1 Formate C-acetyltransferase n=9 Tax=Proteobacteria
           RepID=B8J0R1_DESDA
          Length = 831

 Score =  114 bits (285), Expect = 1e-23,   Method: Compositional matrix adjust.
 Identities = 151/643 (23%), Positives = 256/643 (39%), Gaps = 77/643 (11%)

Query: 179 IGDYRRVALYGIDYLMKD---KLAQFTSLQA--DLENGVNLEQTIRLREEI---AEQHRA 230
           + DY ++   G + + K+   KLA    L A  D E    LE  + + + I   A++H  
Sbjct: 195 VHDYEKILKRGFNSIKKEAREKLAALDPLSAKDDREKRPFLEAVMIVCDAIVLWAKRHAV 254

Query: 231 LG--------------QMKEMAAKYGYDISGPATNAQEAIQWTYFGYL-AAVKSQNGAAM 275
           L               ++  MA    +    PA +  EA Q  +F  + + ++ + G  +
Sbjct: 255 LAREMAEKESDPVRKAELLRMAENAEHVPGEPARDFWEACQSQWFTQMFSRIEQKTGTTI 314

Query: 276 SFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLR---TPEYDELFSGDP 332
           S GR   +   Y ++D +AGKITE +A E+++   M + M  F+    +P       G  
Sbjct: 315 SNGRMDQYFQPYYKQDREAGKITEAQAMELLE--CMWVGMAEFIDMYISPTGGAFNEGYA 372

Query: 333 IWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFK-KFAAKV 391
            W   ++GG   DGR      ++  L +     P   P++      + P  +    A  +
Sbjct: 373 HWEAVTVGGQTPDGRDASNDLTYLILKSKREF-PLHYPDLAARIHSRAPERYLWDVAETI 431

Query: 392 SIDTSSLQYENDDLMRPDFNND--------DYAIACCVSPMIVGKQMQFFG-ARANLAKT 442
              +   +  ND+ + P + +         DYA++ C    +  +     G A  N A  
Sbjct: 432 KYGSGFPKLINDEEIVPLYVSKGATFEEALDYAVSGCTEARMPNRDTYTSGGAYINFAAA 491

Query: 443 MLYAINGGV-----DEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYI-TALN 496
           +   +  G      D+KL ++ G        D      V + +        +QYI   L 
Sbjct: 492 VEMVLRNGRMKKYGDQKLGVETGDPRSFTTWDQFWNAYVEQHLLFLKTAFTQQYIINKLR 551

Query: 497 IIHY-------MHDKYSYEASLMALHDRDVIRTMACGI---AGLSVAADSLSAIK---YA 543
             H+       MHD        + LH   +   +  G     GL    DSL+A+K   + 
Sbjct: 552 AEHFAQPMGSAMHDLCM--KHCIDLHQEQIPEGINLGYFEYMGLGTVVDSLAAVKKLVFE 609

Query: 544 KVKPIRDEDGLAIDFEIEG---------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHT 594
           + K   D+   AID + EG           P +GNND   D +  D ++R   +    ++
Sbjct: 610 EKKLSMDKLIAAIDADFEGYEDVRALLRSAPCYGNNDEYADAIGRD-IDRISVEYGNKYS 668

Query: 595 YRDAIPTQSV--LTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSV 652
             D      V  +  TS+V +GK    TP+GR  G P   G++  HG D  G  A L S 
Sbjct: 669 MSDLGIHNDVRYVPFTSHVPFGKVVSATPNGRTDGFPLSDGSSASHGADVNGPTAVLLSN 728

Query: 653 AKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMN 712
                   +D  +   +I       + E     L   +  +   +       H+  NV+N
Sbjct: 729 CTTKNMGLRDRAARMLNIKFTPKCVEGEQGTEKLVSFIRTFCDLKL-----WHVQFNVVN 783

Query: 713 REMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRT 755
           +  L+ A ++P+KY  L +R++GY+  F  L+ + Q D+I RT
Sbjct: 784 KGTLVAAQKDPQKYRNLIVRIAGYSAYFVDLSPDLQNDLIART 826


>UniRef50_B8FDB2 Formate C-acetyltransferase n=1 Tax=Desulfatibacillum alkenivorans
           AK-01 RepID=B8FDB2_DESAA
          Length = 823

 Score =  114 bits (284), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 132/559 (23%), Positives = 224/559 (40%), Gaps = 72/559 (12%)

Query: 248 PATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVD 307
           PA   +E +Q  +  ++A         +SFGR    L    + DLK G +T ++A E++ 
Sbjct: 281 PARTFKEGLQACWLVHMAMNLEDFEQGLSFGRLDRILLPLYKADLKKGLLTYEKAVEIMA 340

Query: 308 HLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPS 367
              +K      + +   D+ FSG+ +    ++GG+   GR    + S   L+  ++   +
Sbjct: 341 SFQLKTCETIPIYSERIDQYFSGNGVAQGITVGGVNGGGRDCTNELSGLVLDA-FSQIKT 399

Query: 368 PEPNMTILWSEKLPLNFKKFAAKVSI----------DTSSLQ-YENDDLMRPDFNNDDYA 416
            EP + +   +K P  F + AA V+           D + ++  EN  + +P  +  DYA
Sbjct: 400 REPALHVRVHKKTPPWFLEKAAAVAALGCGKPSFFGDKAVIKALENTGMSKP--HARDYA 457

Query: 417 IACCVSPMIVGKQMQFF-GARANLAKTMLYAINGGVDEKLKMQVGPKSEPIK--GDVLNY 473
           +  CV     G+       A  NL   +  A+N G       + G +  P    G     
Sbjct: 458 VIGCVEMASQGRTYNSSDAALFNLPLCLELALNQG------YRFGSRRIPALRFGAPTPS 511

Query: 474 DEVMERMDHFMDWLAKQYITALN----IIHYMHDKYSYEASLMALHDRDVIRTMACG--- 526
            E M+  D  +     Q   ++N    +I  +   Y    +   ++       + CG   
Sbjct: 512 VEEMDAFDQVLRAFKTQVRDSVNEMVKVITMIEQAYRVHRT-TPVNSIITQGCLECGKDV 570

Query: 527 -------------IAGLSVAADSLSAIKYAKVKPIRDEDGLAIDF-------------EI 560
                         AGL+ A DSL A+K       R      +D              EI
Sbjct: 571 TWGGAMYDLTSVQAAGLADAGDSLYALKRVVFDEKRMSLKAFVDILKSNWEGQEKLRQEI 630

Query: 561 EGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNT 620
             ++P++GN D   D +     + +   +      R       + ++T +  +GK TG  
Sbjct: 631 SQKFPRYGNGDKDADRMTQVAADAYTDAVTAHKNSRGGQYIAGIYSMTCHHGFGKATGAL 690

Query: 621 PDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDE 680
           P+GR AG     G +P+ G D+KG  A L S A L      D   +      N     ++
Sbjct: 691 PNGRPAGYRLSNGLSPVDGVDKKGPTAVLQSAASL------DSSQWGNCCALNIKFDGNQ 744

Query: 681 VRKTN----LAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGY 736
            + T     L+GL+  Y +      GG  +  N+++ E L +A E+P  +P + +RV+GY
Sbjct: 745 FKGTKGAKILSGLITAYMNM-----GGMQIQPNILDAETLREAKEDPSAHPGIVVRVAGY 799

Query: 737 AVRFNSLTKEQQQDVITRT 755
              FN L    Q +VI+RT
Sbjct: 800 CAYFNDLQPMVQDEVISRT 818


>UniRef50_D2LJ70 Formate C-acetyltransferase n=1 Tax=Rhodomicrobium vannielii ATCC
           17100 RepID=D2LJ70_RHOVA
          Length = 829

 Score =  110 bits (276), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 139/572 (24%), Positives = 222/572 (38%), Gaps = 97/572 (16%)

Query: 248 PATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVD 307
           P  N +EAIQ+ +F +L     Q+G   S GR   +LD + + D      T ++AQ    
Sbjct: 285 PPRNFREAIQFWWFLHLGNQIEQSGCGSSPGRIGQYLDPWFQADKAQNGFTREDAQAW-- 342

Query: 308 HLVMKLRMVRFLRTPEYDELFSGDP----IWATESIGGMGLDGRTLVTKNSFRFLNTLYT 363
               K   V+ L    Y  L S          T ++GG+   G+   T+     L+T   
Sbjct: 343 ---FKCLFVKILEYGYYQGLISARTNSGHTGHTINLGGLNAAGQDATTELDSVLLDTQIE 399

Query: 364 MGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNNDDYAIA----- 418
           +  + +P +TIL+ + L  +F            +++ E   L +P + N    I      
Sbjct: 400 L-QNIQPTITILYHDGLQEDFL---------LKAIELERTGLGQPQWMNTRLIIERTLAR 449

Query: 419 -----------------CCVSPMIVGKQMQFF-GARANLAKTMLYAINGGVDEKLKMQVG 460
                             CV   + G+      G   NLAK +  A++ G+D      VG
Sbjct: 450 HAKNGITIEDARASINMSCVGTGVEGRTAFIHEGGTFNLAKCIELALHDGIDPGTGFFVG 509

Query: 461 PKSEPIKGDVLN-------YDEVMERMDHFM---------------DWLAKQYITALNII 498
            ++    GD  +       Y   + +++H                 + +A  + +AL   
Sbjct: 510 ART----GDARSFKSFEDFYGAWLRQVEHLFKVQRAFGSVSTKALGETIAPAFRSALYGG 565

Query: 499 HYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVAADSLSAIKYAKVKPIRDEDGL---A 555
                K+ ++  +      D         AG+  AA+SL+AIK+      R   G    A
Sbjct: 566 CLERGKHVFDGGV------DYYLYFVISNAGVD-AANSLAAIKHLVFDTGRLTLGELLDA 618

Query: 556 IDFEIEGE---------YPQFGNNDPRVDDLAVDLVERFMKKIQK--LHTYRDAIPTQSV 604
           +D   EG           P+ GN DP +D L   + +   K         + D I     
Sbjct: 619 VDANFEGHDRIRTLCLNAPKHGNGDPAIDALVRRVYDDAFKTFHAAGYSYFGDHIANIEA 678

Query: 605 LTITSNVVYGKKTGNTPDGRRAGAPFGPGA-NPMHGRDQKGAVASLTSVAKLPFAYAKDG 663
            +++ +  YG KTG  P GR+ G P   G+ +   G D+KG +A + S A+   A     
Sbjct: 679 YSLSIHNYYGLKTGALPSGRQKGRPLTDGSVSATPGTDKKGPLALIQSAAQAVDAVKYGS 738

Query: 664 ISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENP 723
             +     P AL      RK  L  L+  Y        GG H+  NV+  + L  A  NP
Sbjct: 739 NHFNMKFHPTALAGIGGARK--LLSLIKTYMD-----AGGSHIQFNVVTSDTLRKAQANP 791

Query: 724 EKYPQLTIRVSGYAVRFNSLTKEQQQDVITRT 755
           + Y  LT+RV+G++  F  L K  Q ++I RT
Sbjct: 792 DAYKGLTVRVAGFSAYFTRLHKGVQDEIIERT 823


>UniRef50_B8FEM4 Formate C-acetyltransferase n=5 Tax=Proteobacteria
           RepID=B8FEM4_DESAA
          Length = 832

 Score =  110 bits (274), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 146/634 (23%), Positives = 265/634 (41%), Gaps = 112/634 (17%)

Query: 196 DKLAQFTSLQADLENGV-NLEQTIRLREEIAEQHRALGQMKEMAAKYGYDISG-PAT--- 250
           D+L  + ++   LE G+ + ++  RL   +AE      + +E   K        PA    
Sbjct: 233 DRLQNWDAMILVLEAGIRHAKRYARLARTMAENMETDEKRREELLKIAETCERVPARAPR 292

Query: 251 NAQEAIQWTYF-GYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGK-ITEQEAQEMVDH 308
           N QE++Q+ +F    A  ++  GA  +  R   +   Y ++D+   K +T+++A ++V  
Sbjct: 293 NLQESLQYDHFIQIFARTEAHEGAWPA--RPDYYHGPYYDKDVNVDKTLTKEDALDLVGE 350

Query: 309 LVMKLRMV-----RFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYT 363
            +++   V     R+ R  E  +  +G  +W   ++GG+  DG       +  FL     
Sbjct: 351 FMIRAYEVGGFAPRWAR--EGLQGITGTWVW---TLGGVNKDGSDACNDLTVAFLQAARL 405

Query: 364 MGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNNDDYAIA----- 418
           +  S  P     W  K+         K  +     +     L  P   ND   I      
Sbjct: 406 VRVS-NPTFGFRWHPKV---------KDEVLRECFECIRHGLGYPSMRNDPLLIQNAMHW 455

Query: 419 --------------CCVSPMIVGKQ----MQFFGARANLAKTMLYAINGGVDEKLKMQVG 460
                          C+SP    K     M+   A AN AK + YA++ G D  + MQ+G
Sbjct: 456 HGHPLEEARTWVHQACMSPCPTTKHGVQPMRMASATANCAKMVEYALHNGYDHVVGMQMG 515

Query: 461 PKSEPIKGDVL---NYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDR 517
           P++    GD     +++++ +     M+WL    +  +N+  Y   ++     L  + +R
Sbjct: 516 PET----GDAAKFHDFEDLFQAWVKQMEWLTSLLVRTVNLGRYKDPEFFGRPFLSGMSER 571

Query: 518 ------DVIRTMA----CGIAGLSVAA--DSLSAIK---YAKVKPIRDEDGLAIDFEIEG 562
                 DV+  +     C +   +     DSL+A+K   +   K   ++   A+    +G
Sbjct: 572 SVESGLDVVSPVGDRGNCWVTAFTWVENIDSLAAVKKLVFDDKKYTMEQLLTALKANWDG 631

Query: 563 ----------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTI----- 607
                       P++GN+D  VDD+ +    R +++  + H+     P+ +   I     
Sbjct: 632 YEEMRLDFVNNAPKWGNDDDYVDDIML----RCLRETAR-HSRVMKCPSGNSWPILPENV 686

Query: 608 TSNVVYGKKTGNTPDGRRAG-APFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISY 666
           + N+ Y    G  P+GRR G A +  G +P  G D+KG  A L S  K+   +  DG ++
Sbjct: 687 SGNIHYASIVGALPNGRRCGDALYDGGISPGPGLDKKGPSAVLKSCGKID--HVSDGRAF 744

Query: 667 TFSIVPNALGKDDEVRKTNLAG-----LMDGYFHHEASIEGGQHLNVNVMNREMLLDAME 721
                      +  +  T LAG     L   Y    A + G  H+  N+++ E L  A +
Sbjct: 745 LL---------NQRLSPTQLAGEKGYQLWKAYIRTWADL-GLDHVQFNMVSDETLRAAQK 794

Query: 722 NPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRT 755
           +PEKY ++ +RV+GY+  F  ++++ Q ++I RT
Sbjct: 795 DPEKYSEVIVRVAGYSAHFVDISRKTQDNIIQRT 828


>UniRef50_Q56EP5 Vs.6 n=5 Tax=unclassified T4-like viruses RepID=Q56EP5_9CAUD
          Length = 122

 Score =  108 bits (270), Expect = 7e-22,   Method: Composition-based stats.
 Identities = 50/64 (78%), Positives = 58/64 (90%)

Query: 697 EASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTF 756
           E ++EGGQHLNVNV++R  L DA+ NPEKYPQLTIRVSGYAVRFN+LT EQQ+DVITRTF
Sbjct: 59  EPTVEGGQHLNVNVLDRNTLEDAIVNPEKYPQLTIRVSGYAVRFNALTPEQQRDVITRTF 118

Query: 757 TQSM 760
           TQS+
Sbjct: 119 TQSL 122


>UniRef50_A6CWD5 Formate acetyltransferase 2 n=4 Tax=Bacteria RepID=A6CWD5_9VIBR
          Length = 843

 Score =  108 bits (270), Expect = 8e-22,   Method: Compositional matrix adjust.
 Identities = 129/563 (22%), Positives = 220/563 (39%), Gaps = 87/563 (15%)

Query: 254 EAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKL 313
           +AIQ   F         NG ++S+GR   +L  + ++D+    +++    E+++ L +K+
Sbjct: 303 QAIQLFNFAVTLTQIEGNGHSISYGRMDQWLLPFYQKDVNERAVSKSFILELIEVLYVKM 362

Query: 314 RMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMT 373
                L+     ++ +G   +  ES+   G+D       N      T+  +  S    M 
Sbjct: 363 NNPTKLKDKGTVKVRNGRG-FGGESLTLGGVDSEGKDATNDL----TMLMLEASAHTRMM 417

Query: 374 ILW-----SEKLPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNND--------------- 413
             W      EK P   K           +++        P   ND               
Sbjct: 418 NPWVCVRMHEKTPYELK---------IKTIECIRAGYGHPKLFNDTPAIKAMLGKGVSLA 468

Query: 414 ---DYAIACCVSPMIVGKQMQFFGA-RANLAKTMLYAINGG---VDEKLKMQVGPKSEPI 466
              +YA+  CV P I GK+  +  A   N AK M   INGG          Q+GP +  +
Sbjct: 469 EARNYAVVGCVEPTIPGKEHGWLDAGYVNTAKMMEMVINGGRILSGPNAGQQLGPDTGSL 528

Query: 467 KGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDR--DVIRTMA 524
           +     +++V+E +D    +   Q  + LN+   +H        + A  +   +  R M 
Sbjct: 529 E-TYTTFEQVLESVDKQFAYWCDQLCSCLNVTDKIHRMIKPTPYISAFFEGCIETGRDMT 587

Query: 525 CG----------IAGLSVAADSLSAIK--------YAKVKPIRDEDGLAIDFEI------ 560
            G           AG++  ADSLS IK        Y   + +       + +E       
Sbjct: 588 FGGVKYNGTAPQAAGVATCADSLSTIKKLVFDDKKYTGKQLLDAVKNNWVGYEKLYALVN 647

Query: 561 EGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNT 620
             + P +GN++   D+L   + E + + I+     R    +  V T+ +NV  G  T  +
Sbjct: 648 SSKIPHYGNDNDEADELFTFMFECYCRHIKGRINPRGGKFSPGVYTVNANVGMGLYTNAS 707

Query: 621 PDGRRAGAPFGPGANPMH----GRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNAL- 675
            DGR+   P      P+H      D +G  A + SV K+  + A +G         +A+ 
Sbjct: 708 LDGRKNEEPISDNMGPVHTAGGSHDTQGPTAIVNSVTKVDHSLATNGTLLNLRFPEDAVS 767

Query: 676 ---GKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIR 732
              G+D       L   +D Y   +     G H+  N+M+ + +  A +NPE Y  + +R
Sbjct: 768 GIEGRDI------LVSFIDEYISKQ-----GMHVQFNIMSSDKMRAAQKNPELYRDMLVR 816

Query: 733 VSGYAVRFNSLTKEQQQDVITRT 755
           V+GY+  F  L K  Q D+I RT
Sbjct: 817 VAGYSAYFVELGKPLQDDLIQRT 839


>UniRef50_Q70BJ5 Putative uncharacterized protein n=4 Tax=Siphoviridae
           RepID=Q70BJ5_BPBF2
          Length = 122

 Score =  108 bits (270), Expect = 8e-22,   Method: Composition-based stats.
 Identities = 49/61 (80%), Positives = 58/61 (95%)

Query: 700 IEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQS 759
           IEGGQHLNVNV++R+ LLDA ++PEKYPQLTIRVSGYAVRFN+LT+EQQ DVI+RTFTQ+
Sbjct: 62  IEGGQHLNVNVLSRDQLLDAQKHPEKYPQLTIRVSGYAVRFNALTREQQNDVISRTFTQA 121

Query: 760 M 760
           M
Sbjct: 122 M 122


>UniRef50_B7UH18 Autonomous glycyl radical cofactor n=257 Tax=root RepID=GRCA_ECO27
          Length = 127

 Score =  108 bits (269), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 49/64 (76%), Positives = 57/64 (89%)

Query: 697 EASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTF 756
           E  +EGGQHLNVNV+ RE L DA+++PEKYPQLTIRVSGYAVRFNSLT EQQ+DVI RTF
Sbjct: 64  EVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSGYAVRFNSLTPEQQRDVIARTF 123

Query: 757 TQSM 760
           T+S+
Sbjct: 124 TESL 127


>UniRef50_D1NB06 Formate C-acetyltransferase n=1 Tax=Victivallis vadensis ATCC
           BAA-548 RepID=D1NB06_9BACT
          Length = 712

 Score =  107 bits (266), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 125/514 (24%), Positives = 214/514 (41%), Gaps = 83/514 (16%)

Query: 287 YIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATE-SIGGM--- 342
           +  RDL AG++  ++A+E+     +K    +F    +         +W      GGM   
Sbjct: 240 FYRRDLAAGRLNREQAKEL-----LKFYWTKFFAQTQ-------GKLWGKNFCFGGMDGD 287

Query: 343 GLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAK-VSIDTSSLQYE 401
           G D    +T+  F     L T+    +P +++     LP      AA+ V    +++ + 
Sbjct: 288 GSDACNELTELGFEVYRELRTV----DPKLSLRVHGGLPEKVLLQAAECVCRGRTAVVFA 343

Query: 402 NDDLMRPDFNND--------DYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDE 453
           ND++ +  F           D+    C  P ++GK++         + + L+ +   V+ 
Sbjct: 344 NDEIAKEMFVRRGKLPEEIADFIPVGCYEPCVMGKEL-------CCSMSTLFNLAKAVEL 396

Query: 454 KLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKY---SYEAS 510
            ++    P+         ++ E++ER   ++  + ++   AL +      ++   +    
Sbjct: 397 LMENPAPPR---------DFGELLER---YLGLVREKLDDALELTRRWELRWPEINPSPL 444

Query: 511 LMALHD------RDV----IRTMACGI--AGLSVAADSLSAIKYAKVKPIRD-----EDG 553
           L    D      RDV     +  + G+  AGL  AADSL+A++    +  R         
Sbjct: 445 LSGTMDSCFEKGRDVSAAGTKYSSSGVMCAGLGSAADSLTALRILLFEERRCTWEELRAT 504

Query: 554 LAIDFE--------IEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVL 605
           L  D+E        + G  P++GNN P  D LA  + +   ++I +    RD      + 
Sbjct: 505 LKADWEGREPLRLYVSGRLPKWGNNLPEPDALARKIADAVAERINRAPNARDGFFQTGMW 564

Query: 606 TITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGIS 665
           +I     YG+ TG TPDGRRAG P          +D++G  A L S AKL  A   DG  
Sbjct: 565 SIDWAQRYGRMTGATPDGRRAGEPLSKNLGAAIAKDRRGVAALLHSAAKLDQAEFPDGAV 624

Query: 666 YTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEK 725
               + P+ + K  E  K  +A L+  YF       GG  +  N+++ + L  A   PEK
Sbjct: 625 LDVMLHPSMV-KGKEGPKV-VADLVRTYFEA-----GGLFIQFNILDVDTLRRARREPEK 677

Query: 726 YPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQS 759
           Y  + IRV G+ VRF  L    Q+  I    ++S
Sbjct: 678 YSSVQIRVCGWNVRFIDLDPAAQELFIQEAESKS 711


>UniRef50_Q312S2 Formate C-acetyltransferase n=9 Tax=Bacteria RepID=Q312S2_DESDG
          Length = 829

 Score =  105 bits (263), Expect = 6e-21,   Method: Compositional matrix adjust.
 Identities = 129/579 (22%), Positives = 241/579 (41%), Gaps = 68/579 (11%)

Query: 232 GQMKEMAAKYGYDISGPATNAQEAIQWTYFGYL-AAVKSQNGAAMSFGRTSTFLDVYIER 290
            +++ MA    +    PA N  EA+Q  +F  + + ++ + G  +S GR   +   +  +
Sbjct: 269 AELETMAEICAWVPENPARNFYEAVQAQWFTQMFSRLEQKTGTIVSNGRMDQYFWPFYRK 328

Query: 291 DLKAGKITEQEAQEMVDHLVMKL-RMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTL 349
           D++ G+ITE+ A E+++ + + + + V    +P       G   W   +IGG    G   
Sbjct: 329 DIEEGRITEESALELLECMWVGMAQYVDLYISPAGGAFNEGYAHWEAVTIGGQTPQGLDA 388

Query: 350 VTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNF-KKFAAKVSIDTSSLQYENDDLMRP 408
               ++ FL +     P   P++      + P  +    A  +   +   +  ND+ + P
Sbjct: 389 TNDLTYLFLKSKREF-PLHYPDLAARIHSRSPERYLHDVAETIKFGSGFPKLINDEEIVP 447

Query: 409 DFNND--------DYAIACCVSPMIVGKQMQFFG-ARANLAKTMLYAINGGV-----DEK 454
            + +         DYA++ C    +  +     G A  N A  +   +  G      + +
Sbjct: 448 LYVSKGASFEEALDYAVSGCTEARMPNRDTYTSGGAYINFAAALEMVLYNGRMLKYGENE 507

Query: 455 LKMQVGPKSEPIKGDVLN--YDEVMERMDHFMD--WLAKQYITALNIIHY-------MHD 503
           L ++ G   +P + +     ++  + + +HF+   ++ +  I  +   H+       +HD
Sbjct: 508 LGLETG---DPTRFETWEEFWNAYVLQHEHFLRAAFIQQHIINNVRARHFAQPMGSALHD 564

Query: 504 KYSYEASLMALHDRDVIRTMACGI---AGLSVAADSLSAIK---YAKVKPIRDEDGLAID 557
                   + LH   +   +  G     G     DSL+AIK   +   K    E   A+ 
Sbjct: 565 LCM--KHCLDLHTPQIPEGINLGYFEYMGFGTVVDSLAAIKKLVFEDKKLTMQEVIEALK 622

Query: 558 FEIEGE---------YPQFGNNDPRVDDLAVDL----VERFMKKIQKLHTYRDAIPTQSV 604
              EG+          P +GNND   D +A ++    V+   +   +L  + D       
Sbjct: 623 CNFEGKEDVQQMLKSAPCYGNNDEYADSIAREIDAISVKYGRRYSPELGMHNDV----RY 678

Query: 605 LTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTS-VAKLPFAYAKDG 663
           +  TS+V +GK    TP+GR A  P   G++  HG D  G  A L S  +   + Y +D 
Sbjct: 679 VPFTSHVPFGKVVSATPNGRLAWTPLSDGSSASHGADVNGPTAVLQSNFSSKNYGY-RDR 737

Query: 664 ISYTFSI--VPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAME 721
            +   +I   P  +  D+   K  L   +  +   +       H+  NV+NR+ L+ A +
Sbjct: 738 AARMLNIKFTPKCVEGDEGTEK--LVSFIRTFCDLKL-----WHVQFNVINRDTLIAAQK 790

Query: 722 NPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQSM 760
           +PEKY  L +R++GY+  F  L+ + Q D+I RT   +M
Sbjct: 791 DPEKYRSLIVRIAGYSAYFVDLSPDLQNDLIARTQHDAM 829


>UniRef50_B0NGB8 Putative uncharacterized protein n=3 Tax=Bacteria
           RepID=B0NGB8_EUBSP
          Length = 794

 Score =  105 bits (262), Expect = 7e-21,   Method: Compositional matrix adjust.
 Identities = 155/649 (23%), Positives = 261/649 (40%), Gaps = 85/649 (13%)

Query: 176 GRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLEN-------GVNLEQTIRLR---EEIA 225
           G +I D R V   G+D L K+++ +  + +AD +         + L+  + +    EE+A
Sbjct: 163 GHLIPDMRPVLKIGVDGL-KEQIRRHKAAEADADKKDYYDAMDIALDAVLVIAGRYEELA 221

Query: 226 EQH--RALGQMKE----MAAKYGYDISGPATNAQEAIQWTYFGY--LAAVKSQNGAAMSF 277
            +   ++ G +KE    MA   G      A+N  EAIQ     +  +   ++ N  A S 
Sbjct: 222 REKAAKSEGAVKERFEVMADALGKVPRQGASNLYEAIQSFILMWQVMCLEQTPNPYAFSV 281

Query: 278 GRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATE 337
           G      + Y        +  E   ++M   L+  L +  F    +     S D I    
Sbjct: 282 GNADRIFEPY--------RQAEDTGRDMTAALLKHLLV--FYNVADRSWAISQDLI---- 327

Query: 338 SIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSS 397
            IGG    G  +    S+  L+  Y M   P+P +++   +  P    +   +       
Sbjct: 328 -IGGKSNTGEDMTNPTSYALLDAYYDMN-LPQPILSVKLHKDTPDELYESLGRFLFTPGC 385

Query: 398 L--QYENDDLM----------RPDFNNDDYAIACCVSPMIVGKQM-QFFGARANLAKTML 444
           L   + NDD +           P+ + +DY++A C  P+I+GK       +  N+AK + 
Sbjct: 386 LTPSFFNDDSVFEILKEKNHVEPE-DLEDYSVAGCQEPLIMGKDNGNTTNSWLNMAKVLE 444

Query: 445 YAINGGVDEKLKMQVGPKSE----PIKGDVLN--YDEVMERMDHFMDWLAKQYITALNII 498
            ++NGGV      + G  +E      + DVL        + ++ ++D + +    A   I
Sbjct: 445 LSLNGGVSTISGRKFGKSNEENGYKEEVDVLKNIRSTFYQNLEEYVDQMVECANAASEAI 504

Query: 499 HYMHDKYSYEASLMA-----LHDRDV------IRTMACGIAGLSVAADSLSAIKYAKVKP 547
             +  +  + ++LM      +  RD            C I GLSV ADS +AI     + 
Sbjct: 505 SLL--QVPFLSALMGGIETGIDTRDTRNQGTKYNGSGCLIHGLSVVADSFAAIDRLLEER 562

Query: 548 IRDE----DGLAIDFEIEGEYPQF-------GNNDPRVDDLAVDLVERFMKKIQKLHTYR 596
            +D     + L  +FE + +  Q+       GNN   VDD A ++  R    +     Y 
Sbjct: 563 PKDAGRMLEALRDNFEHDQQMRQYLMKAEKYGNNTANVDDEAAEIAARVSDMVSSKKNYL 622

Query: 597 DAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLP 656
                    + +++++YG   G TPDGR A    G G +P++G    G    + S  KLP
Sbjct: 623 GNPFRADWASPSTHLLYGYWVGATPDGRMAREQLGYGIDPLYGEAHSGLGFRIMSNMKLP 682

Query: 657 FAYAKDGISYTFSIVPNALGKDD-EVRKTNLAGLMDGYFHHEASIEGGQ--HLNVNVMNR 713
           F     G +    I PN       E +       + G   +    EG    +L VNV   
Sbjct: 683 FEKMNGGCASHLGINPNYFKTSSYEEKGLEFKNKIIGPLFYNPKKEGISPFYLYVNVTTP 742

Query: 714 EMLLDAMENPEKYPQ---LTIRVSGYAVRFNSLTKEQQQDVITRTFTQS 759
           EML   + +P+KY       +R+ G  V F  L+ + Q+D+I R   +S
Sbjct: 743 EMLRKVLADPKKYAPSGVYIMRIHGTFVNFLDLSPDIQEDIIKRLDMES 791


>UniRef50_B7BHI6 Putative uncharacterized protein (Fragment) n=1 Tax=Parabacteroides
           johnsonii DSM 18315 RepID=B7BHI6_9PORP
          Length = 178

 Score =  105 bits (261), Expect = 9e-21,   Method: Composition-based stats.
 Identities = 49/104 (47%), Positives = 68/104 (65%), Gaps = 1/104 (0%)

Query: 12  WEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLWDKVMEGVKLENRTHAP 71
           W  F    W+ E+NVRDFIQ NY PY+GD++FL  ++E T  +W+K+ E  K+E R    
Sbjct: 76  WAQFKGETWKKEINVRDFIQNNYKPYDGDDTFLVPSSEKTKKVWNKLTEMFKVE-REKGV 134

Query: 72  VDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGG 115
            D +T +   I ++  GYI+K+ E IVGLQT+APLKR + P GG
Sbjct: 135 YDAETKLPQGIDTYGPGYIDKENEVIVGLQTDAPLKRGIFPKGG 178


>UniRef50_Q5E2Y6 Autonomous glycyl radical cofactor n=6 Tax=Proteobacteria
           RepID=GRCA_VIBF1
          Length = 125

 Score =  104 bits (259), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 47/61 (77%), Positives = 55/61 (90%)

Query: 700 IEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQS 759
           IEGGQHLNVNV+ R+ L DA+++PE YPQLTIRVSGYAVRFNSLT EQQ+DVI RTFT+S
Sbjct: 65  IEGGQHLNVNVLQRDTLEDAVKHPENYPQLTIRVSGYAVRFNSLTTEQQKDVIARTFTES 124

Query: 760 M 760
           +
Sbjct: 125 L 125


>UniRef50_Q6RHV7 Putative uncharacterized protein vs.6 n=1 Tax=Aeromonas phage 65
           RepID=Q6RHV7_9CAUD
          Length = 120

 Score =  103 bits (258), Expect = 2e-20,   Method: Composition-based stats.
 Identities = 47/61 (77%), Positives = 56/61 (91%)

Query: 700 IEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQS 759
           +EGGQHLNVNV+N+E L DA++ PEKYPQLTIRVSGYAVRFNSLT EQQ+DV++RTFT S
Sbjct: 60  VEGGQHLNVNVLNKETLEDAIKFPEKYPQLTIRVSGYAVRFNSLTPEQQRDVVSRTFTAS 119

Query: 760 M 760
           +
Sbjct: 120 L 120


>UniRef50_B1BA70 HpdB protein n=1 Tax=Clostridium botulinum C str. Eklund
           RepID=B1BA70_CLOBO
          Length = 841

 Score =  100 bits (250), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 66/194 (34%), Positives = 99/194 (51%), Gaps = 13/194 (6%)

Query: 565 PQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGR 624
           P+FGN+D  VD + VDL E +        TY       + L+I+++  +G+    TPDGR
Sbjct: 651 PKFGNDDDYVDTIFVDLWEHYNNTCLSETTYLGLQWIPAALSISAHGPFGRVCSATPDGR 710

Query: 625 RAGAPFGPG---ANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEV 681
            AG     G   A P  G D+ G +A L S  KL     +  +     + PNA+   D  
Sbjct: 711 VAGVSLTDGILSATP--GTDKNGPIALLNSGVKLDSVKMR-SVQLNMKLHPNAIKNVDGS 767

Query: 682 RKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFN 741
           +K  L  L+  YF      +GG H+  NV++ ++L DA  NPEKY  L +RV+G++  + 
Sbjct: 768 KK--LVNLIRTYFE-----QGGYHIQFNVVDSKILRDAQHNPEKYRDLIVRVAGFSAYWV 820

Query: 742 SLTKEQQQDVITRT 755
            L+K  Q ++I RT
Sbjct: 821 ELSKPIQDEIIART 834


>UniRef50_C0CUZ2 Putative uncharacterized protein n=1 Tax=Clostridium asparagiforme
           DSM 15981 RepID=C0CUZ2_9CLOT
          Length = 759

 Score =  100 bits (249), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 143/584 (24%), Positives = 237/584 (40%), Gaps = 83/584 (14%)

Query: 215 EQTIRLREEIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQ--WTYFGYLAAVKSQNG 272
           +Q + L  +  ++ R  G+++ MA            +  EA+Q  W Y G +A +     
Sbjct: 214 DQAMELLAQAGDEKRK-GELRRMAQALEAIAERAPGSMMEALQLVWIY-GIMAPL----- 266

Query: 273 AAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDP 332
             + FGR   +L  +   D+  G +TE+EA  ++     ++           D L S   
Sbjct: 267 --LQFGRLDVYLGDWYAHDIDNGVLTEEEALALLQSYFRQI-----------DSLDSETD 313

Query: 333 IWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVS 392
                 +GG G        +     L    T+     P  T+ ++ + P      A +  
Sbjct: 314 CRVI--VGGYGRRNPENADRLCMTALEACRTV-REILPQFTLRFNRETPECVWDAAMRCI 370

Query: 393 ID--TSSLQYENDDLMRPDFNNDDYAI---ACCVSPMIVGKQMQF----FGARA---NLA 440
            +  T  L Y NDD++ P   N  +     A    P+  G +M+F    FG  +   N  
Sbjct: 371 EEGRTYPLLY-NDDVLVPGLMNAFHVSRERAETYVPLGCG-EMEFDHYSFGTPSGSLNTL 428

Query: 441 KTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVM----ERMDHFMDWLAKQYITALN 496
           K +  A+ GG +  +   +G + +PI      ++E      E + H+++  A        
Sbjct: 429 KILELAVRGGYEPIMDWHLGKQLKPIT-QCNTFEEFFQVYKENLQHYIEAQAIFEKYEYE 487

Query: 497 IIHYMHDKYSYEASLM--ALHDRDVIRTMAC-------GIAGLSVAADSLSAIK--YAKV 545
           I   MH  + Y + L    L     I    C        + G+  A +SL+A+K    + 
Sbjct: 488 ITGKMH-SFMYVSMLYDGVLESGKAIFDGGCRYLAGTLELYGVVNAVNSLAAVKKLVYED 546

Query: 546 KPIRDEDGL-AIDFEIEG---------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTY 595
           + +  ED L A++    G         + P++GN+D  VD + V+L +   K I    + 
Sbjct: 547 RTVSAEDLLRAMNDNFVGWEVLRRQLLDVPKYGNDDDYVDRIFVELHDWLCKTIS---SQ 603

Query: 596 RDAIPTQSVLTI----TSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTS 651
            + +  +S L +      N   G+  G TPDGR+AG P     NP  G D+ G  A L S
Sbjct: 604 AEKVGLKSYLAVNINNAQNTTLGRWVGATPDGRKAGMPMANANNPSSGSDKNGLTAMLNS 663

Query: 652 VAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVM 711
           + K P      G+     +         E  +  + GL+  YF       GG HL + V+
Sbjct: 664 ILK-PRHDNHAGMVQNLRLSRETF----EQNREKVKGLIRNYFDR-----GGAHLMITVV 713

Query: 712 NREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRT 755
            +E L  AME+PE Y  L +RV G + R+  L K+ QQ++  R 
Sbjct: 714 GKEDLKKAMEHPEDYQDLIVRVGGLSARYVQLKKDVQQEIYDRA 757


>UniRef50_A6CVH9 Formate C-acetyltransferase n=10 Tax=Bacteria RepID=A6CVH9_9VIBR
          Length = 763

 Score = 98.6 bits (244), Expect = 8e-19,   Method: Compositional matrix adjust.
 Identities = 63/197 (31%), Positives = 102/197 (51%), Gaps = 19/197 (9%)

Query: 565 PQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITS--NVVYGKKTGNTPD 622
           P+FGN+D  VDD+AV++ E     I K    +  + +  V+ I +  N  +G+ T  + D
Sbjct: 579 PKFGNDDAYVDDIAVEMHEYICNGI-KDSAAKVGMDSYLVVIINNQVNTEWGRATSASAD 637

Query: 623 GRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLP---FAYAKDGISYTFSIVPNALGKDD 679
           GR  G       NP  G D+ G  A L S+AKL     A +   + ++ ++  N      
Sbjct: 638 GRHTGVYMSNANNPQSGADKNGPTAMLNSLAKLKAEIHAGSVQNMKFSKNMYQN------ 691

Query: 680 EVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVR 739
             ++  +  L+DGYF      +GG  + V+V+ +  L DA  NPEKYP L +RV G++ +
Sbjct: 692 --KRMIVEALLDGYFE-----QGGPQIMVSVVGKGELEDAYHNPEKYPNLVVRVGGFSAK 744

Query: 740 FNSLTKEQQQDVITRTF 756
           F +L K+ Q +++ RT 
Sbjct: 745 FVNLDKDVQLEILNRTL 761


>UniRef50_B8FMK7 Formate C-acetyltransferase n=1 Tax=Desulfatibacillum alkenivorans
           AK-01 RepID=B8FMK7_DESAA
          Length = 838

 Score = 97.1 bits (240), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 153/648 (23%), Positives = 249/648 (38%), Gaps = 127/648 (19%)

Query: 195 KDKLAQFTSLQADLENGVNLEQTIRLREEIAEQHRALGQMKEMAAKYGYDISGPATNAQE 254
           +D  A++ SL  D+E     E     +EE+A           MAA   +    P  +  E
Sbjct: 224 RDLAARYASLIRDMEQK---ESDPERKEELAR----------MAANLDHTPWNPPRDFWE 270

Query: 255 AIQWTYFGYLAAVKSQN--GAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMK 312
           AIQ  +  ++  +  +N  G  +SFGR   +L  Y E  +  G +  +  +E++    + 
Sbjct: 271 AIQALWLTHMLVLSDENYPGPGVSFGRVDQYLLPYWEASMAQG-MDREWGKEILKCFWIH 329

Query: 313 LRMV--RFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGP--SP 368
                   +RT     + +G     T  + GMG DG  L    ++ FL  +  M P   P
Sbjct: 330 ANTAYDAMIRTGANGGITAGYGQLIT--LSGMGPDGTDLTNDLTYVFLEVIDEMSPILEP 387

Query: 369 EPNM----------------TILWSEKLP--LNFKKFAAKVSIDTSSLQYENDDLMRPDF 410
           +PN+                 I  S+  P  LNF + +       + +  E +   R D 
Sbjct: 388 KPNVRLHANTPEELYDHIIDMIAESQGAPFLLNFDERS------MAGMMREAEKAGRQDL 441

Query: 411 NNDD----YAIACCVSPMIVGKQMQ-FFGARANLAKTMLYAINGGVDE-KLKMQVGPKSE 464
            N+     YA   C+   +VG           NL K + +A+ GG D    K  +  K  
Sbjct: 442 INESNVWQYAPVGCLENTMVGNDRSGTVDINLNLLKAVEFALTGGADLLPYKDTIMGKEY 501

Query: 465 PIKGDVLNYDEVME--RMDHFMDWLAKQYITALNIIHYMHDKY-SYEASLMALHDRDVIR 521
           PI    +   +  E    + F    AKQ     +II    D Y + E+   A H    + 
Sbjct: 502 PIDASGIPTGDPTEFTVFEEFFAAFAKQ---TRHIIKKAMDLYETSESVRAAYHPTPYLS 558

Query: 522 TMACGIA---------------------GLSVAADSLSAIKY-----------AKVKPIR 549
            +  G A                       +   DSL A+KY             ++ ++
Sbjct: 559 CLVKGCAEKGKDVTQGGAELSFVTIEAVTFATTVDSLLAVKYLVFDEKICTMAELIQALK 618

Query: 550 D--EDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTY---RDAIPTQSV 604
           D  E    +    + + P++G +D   D++A  +++ + ++  K  T    R A P   +
Sbjct: 619 DNWEGHDILMARAKFKAPKYGRDDDEADEMARKVMDLWTEETWKHKTQSTGRQARP--GM 676

Query: 605 LTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAK---------- 654
           L+    V  G     +PDGR  G        P +G D  G  ++  SV K          
Sbjct: 677 LSWNYWVGDGYILHASPDGRPKGQFLSNAICPTNGADINGPTSNANSVGKALGGRKPGKG 736

Query: 655 --------LPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHL 706
                   LP     +G S+T +  P+ L   D + K      + GY  +     GG  L
Sbjct: 737 DFGDYLNSLP-----NGASHTITFNPSILA--DPLHKEKFKAYLKGYVQN-----GGTAL 784

Query: 707 NVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITR 754
            +N+++ +ML DA +NP  Y  L +R++GY   F S+ KE Q +VI R
Sbjct: 785 QINMLDADMLKDAQKNPADYRHLLVRITGYNAYFTSIGKELQDEVIAR 832


>UniRef50_D1ANR4 Formate C-acetyltransferase n=1 Tax=Sebaldella termitidis ATCC
           33386 RepID=D1ANR4_SEBTE
          Length = 768

 Score = 96.7 bits (239), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 151/640 (23%), Positives = 262/640 (40%), Gaps = 110/640 (17%)

Query: 181 DYRRVALYGIDYL---MKDKL---AQFTSLQADLENGVNLEQTIRL-REEIAEQHRALGQ 233
           DY ++   GID L   +KDKL   A+   L+  LE     E+T+   R+ IA+  +  G+
Sbjct: 172 DYPKLLDNGIDGLKNIIKDKLNKSAENEFLKIALETLDLYEKTVDYERKLIAKAMKNAGE 231

Query: 234 --MKEMAAKYGYDISGPATNA----QEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVY 287
             +KE+       +S    N      +A+Q  +   L A        +++GR   +L  Y
Sbjct: 232 ERLKELLL-IDESLSAIRNNKPKTFHQALQMFWLYALLA------GCINYGRLDDYLGPY 284

Query: 288 IERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGR 347
           ++ DL+ G ITE++A   +  L     ++   RT     + +G         G   ++  
Sbjct: 285 LKHDLETGLITEEDAYRYLKSL---WTLIENRRTTVNGRIITG-------GYGRKNIEAA 334

Query: 348 TLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKV-------------SID 394
            + T+ + +       +    EP  T+  +++ P +    A                 I+
Sbjct: 335 DIFTRIALKVTKDCKYV----EPQFTLRITKETPQDIMDMAYDCIGEGVTYPTLYNDEIN 390

Query: 395 TSSLQYENDDLMRPDFNN-DDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDE 453
             ++ Y     MR D    + Y    C   +I G+ +       NL K +   +N G+D 
Sbjct: 391 IPAVMYS----MRVDRETAEQYVPFGCGEFVIQGQSVGTPNILINLLKILNITLNKGID- 445

Query: 454 KLKMQVGPKSEPI----KGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEA 509
              M    KS  I      +  ++DE+  +    +D+       A    ++ ++  + E 
Sbjct: 446 --PMDGKKKSGNIIMKDPDEYRSFDELYSKYKELLDYYLDLSADAQ---YHSYEVMNREV 500

Query: 510 SLMALHDRDVIRTMACGIAGLSV-------------------AADSLSAIK---YAKVKP 547
           S M       I T  C   G S+                   ++D+L AIK   + + K 
Sbjct: 501 SFMFAS----ILTNDCISRGKSILDGGVRYLGGTNETYGNINSSDALYAIKTLVFDQKKY 556

Query: 548 IRDEDGLAIDFEIEG---------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDA 598
              E   A     +G            ++GN+    D+LA DL E F+ K  +    +  
Sbjct: 557 TLKELNEAAHHNFKGYEKIREELWNCGKYGNDIEEADELANDLYE-FVAKGNRDRGLKKG 615

Query: 599 IPTQSVLTIT--SNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLP 656
           +    ++     +N  +G+KT  + DGR +G    P  NP  G D+ G  A L S+++  
Sbjct: 616 MDYFLIVISNNQTNTEWGRKTSASLDGRYSGQFMNPANNPQGGADKNGPTALLNSLSRFD 675

Query: 657 FAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREML 716
             Y    +       PN   K+ ++ K+    L D YF      +GG HL V V++R +L
Sbjct: 676 AKYHGGSVQ-NIKFTPNMFNKNRKIIKS----LFDTYFK-----KGGCHLMVTVVDRGVL 725

Query: 717 LDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTF 756
            DA ++PEKYP L +RVSG++  F +L ++ Q +V++R  
Sbjct: 726 KDAQDHPEKYPDLVVRVSGFSAIFVNLERDVQDEVMSRVL 765


>UniRef50_C6BT93 Formate C-acetyltransferase n=6 Tax=Desulfovibrio
           RepID=C6BT93_DESAD
          Length = 817

 Score = 96.7 bits (239), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 139/567 (24%), Positives = 240/567 (42%), Gaps = 86/567 (15%)

Query: 248 PATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVD 307
           PA N +EAIQ  +F +L     Q   A+S GR   ++  + ++D+  G +T ++   M  
Sbjct: 271 PARNFREAIQSFWFTHLCVATEQMACAVSPGRYGQYMYPFFKKDIDEGNLTREQVLTM-- 328

Query: 308 HLVMKLRMVRFLRTPEYD----ELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYT 363
              +K + +R L   EY      L        + +IGG+  DG    T+     L T   
Sbjct: 329 ---LKFQWIRHLELGEYQGNSYALTLSGHTGQSMTIGGVDKDGNDASTELEELMLETQIQ 385

Query: 364 MGPSPEPNMTILWSEKLPLNF-KKFAAKVSIDTSSLQYENDDLM----------RPDFNN 412
           M  S +P +T+L+  KL  ++ +K    +   +   Q  N++++           PD   
Sbjct: 386 M-KSIQPTLTLLYHPKLKESYMQKVVECIRGGSGQPQILNNNVVIQRTLARFAQYPDGIT 444

Query: 413 DDYAIAC----CVSPMIVGKQMQFFGA--RANLAKTMLYAINGGVDEKLKMQVGPKS-EP 465
            + A  C    CVS  + GK   F     +  LAK +   +N G     K  VG ++ +P
Sbjct: 445 LEDARNCGNYGCVSTGVCGKG-SFITQEDQPCLAKVVELVLNNGKCPVTKKMVGAETGDP 503

Query: 466 IKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLM--------ALHDR 517
              +   ++++ E +   +D L +        I   H   S  A L         A++D 
Sbjct: 504 TTFET--FEDLYEGVKGQLDNLFR--------ISRAHSDLSQMARLQVVPSVFRSAMYDG 553

Query: 518 DVIRTMACGIAGLSV-------------AADSLSAIKYA--KVKPIRDED---GLAIDFE 559
            + + M C  AG +              AA+S+ AIK+     K +  E+    L  +FE
Sbjct: 554 CIEKGM-CEEAGGTRYPQVNPIMTAGVDAANSILAIKHLVYDTKAVTMEELIQALKANFE 612

Query: 560 IEGEYPQFGNNDPRVDDLAVDL---VERFMKKIQKLHTYR--DAIPTQSVL---TITSNV 611
              E  Q   + P+  +   D+   V+RF + +  +H  +  D    ++ L   +++ + 
Sbjct: 613 GYEELRQMCFDAPKHGNDYEDVQAFVQRFYRDVDAIHHAQGPDCFGQRTPLDAYSLSYHN 672

Query: 612 VYGKKTGNTPDGRRAGAPFGPGA-NPMHGRDQKGAVASLTSVAKL--PFAYAKDGISYTF 668
            +G   G  P+GR+AG     G+ + M G D++G  A + S A+      Y  +  +  F
Sbjct: 673 YFGGMMGALPNGRKAGVALTDGSVSAMPGTDKEGITALIKSGAEAIDTVRYGANHFNVKF 732

Query: 669 SIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQ 728
           S  P+ L      +   L  L+  Y        GG H+  N ++ + L DA +NP+ Y  
Sbjct: 733 S--PSVLEGPQGAK--TLISLIKTYCDF-----GGSHIQFNCVSSDTLKDAQQNPQDYSD 783

Query: 729 LTIRVSGYAVRFNSLTKEQQQDVITRT 755
           L +RV+G++  F  L    Q ++I RT
Sbjct: 784 LIVRVAGFSAYFTRLDCGVQNEIIKRT 810


>UniRef50_A6G8C6 Pyruvate formate-lyase 2 (PflD) n=1 Tax=Plesiocystis pacifica SIR-1
           RepID=A6G8C6_9DELT
          Length = 889

 Score = 94.0 bits (232), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 59/220 (26%), Positives = 111/220 (50%), Gaps = 9/220 (4%)

Query: 536 SLSAIKYAKVKPIRDEDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTY 595
           SL  ++ A  +   DE+  A+   +    P++G +    +  A  + E + + +++    
Sbjct: 652 SLGRLRRALARDFVDEE--ALRQRLRNHVPKYGQDAGPPERWARRVAELYAELLREHLNP 709

Query: 596 RDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKL 655
           R         ++T++V +G++ G  P GR+AG P   G +P  G D +G  ASL SVA +
Sbjct: 710 RHGPYAPGFWSMTTHVGFGRRLGALPSGRKAGRPLANGLSPSSGADNRGPTASLLSVAAV 769

Query: 656 PFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREM 715
              +  +G +   ++ P+ +    EV    +  L+ GYF       GG  +  NV++   
Sbjct: 770 SGGFVGNGYALNETLDPSFV--RGEVGLARIDQLVRGYF-----AAGGNQVQFNVLDTAE 822

Query: 716 LLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRT 755
           L+DA  +PE++  L +R+SGY+  FN L++  + ++I R+
Sbjct: 823 LVDAKAHPERHRGLVVRISGYSAYFNDLSEAMKDELIARS 862



 Score = 51.6 bits (122), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 51/212 (24%), Positives = 88/212 (41%), Gaps = 17/212 (8%)

Query: 223 EIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTST 282
           E+AE      +++E+AA        PA    EA+Q  +  ++   +      +SFGR   
Sbjct: 277 EVAEDPERAAELRELAAVLARVPIEPARTYHEALQSVFTTHVVIHQESFQHGISFGRIDQ 336

Query: 283 FLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGG- 341
           +L  +++ DL+AG++ E  A E+    + K      L      E FSG    +  ++GG 
Sbjct: 337 YLAPFLDADLEAGRLDEARAVELTGCFLAKAAEQLPLFNAMSTEFFSGLSSASGLTLGGT 396

Query: 342 ---MGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSSL 398
               G D  T VT+      + L       +PN+ +      P   ++ A  V  +   +
Sbjct: 397 DPRTGADATTSVTRAILLAYHQLRLR----QPNLHLRVHPGTPEGLRRLAYAVLREGGGM 452

Query: 399 Q--YEND---DLMR----PDFNNDDYAIACCV 421
              + ++   D +R    P    +DYAI  CV
Sbjct: 453 PALFRDEGVVDAIRGLGVPHEAAEDYAIVGCV 484


>UniRef50_Q76Z52 Putative uncharacterized protein vs.6 n=1 Tax=Aeromonas phage Aeh1
           RepID=Q76Z52_9CAUD
          Length = 125

 Score = 92.0 bits (227), Expect = 7e-17,   Method: Compositional matrix adjust.
 Identities = 39/64 (60%), Positives = 53/64 (82%)

Query: 697 EASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTF 756
           E+    GQHLNVNV++RE L+ A+E+P +YP L +R+SGYAVRFN+LT EQQ+D++TRTF
Sbjct: 62  ESVQHAGQHLNVNVLSREHLMLAIEDPNRYPNLVVRISGYAVRFNALTPEQQRDIVTRTF 121

Query: 757 TQSM 760
           T+ M
Sbjct: 122 TKHM 125


>UniRef50_D1N4L3 Formate C-acetyltransferase n=1 Tax=Victivallis vadensis ATCC
           BAA-548 RepID=D1N4L3_9BACT
          Length = 716

 Score = 91.3 bits (225), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 130/585 (22%), Positives = 228/585 (38%), Gaps = 76/585 (12%)

Query: 204 LQADLENGVNLEQTIRLREEIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQW-TYFG 262
           L A+LE    +   I      AE     G+++ +  +   D   P    +EA QW  +F 
Sbjct: 174 LNAELEALAGIRNWIHRTAMAAE-----GELRRINLRLEND---PPETLREACQWIAWFN 225

Query: 263 YLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTP 322
             +   +++GA    G+    L  Y ERD+ AG+I +++A   +  L+        L  P
Sbjct: 226 MASRTYNRDGAG---GQLDEILRPYYERDIAAGRIDDEDAVYYIACLL--------LNDP 274

Query: 323 EYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPL 382
            Y ++   DP            +G+   ++ SF  L   + +      N+TI   +++  
Sbjct: 275 HYYQIGGPDP------------NGKDQTSRISFLILEAAHAL--KTPCNLTIRVHDRMDE 320

Query: 383 NFKKFAAKVSIDTS--SLQYENDDLMRPDFNNDDYAIACCVSPMIVGKQMQFFGARA--- 437
              +   ++ ++ +    ++  D+ +   F  + Y+I      + +G        R    
Sbjct: 321 KLFRRGVEILLEDNLGYPRFSGDNALIEGFMRNGYSIELARERIALGCNWMSIPGREYTL 380

Query: 438 ------NLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQY 491
                 N+ K    A N   D   K  +G   +  +  +      +     F   LA QY
Sbjct: 381 NDTVKINMMKVFEVAFNEIADSG-KFSLGALHKCYQKHLARAAFCIAEGLDFH--LAHQY 437

Query: 492 ITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVAADSLSAIKYAKVK----- 546
                ++  +      E    A H       M C  AGL+V ADS +A++   V+     
Sbjct: 438 RNEPELLLNLLCYGPIEKGRDASHGGVDFYNMCCDGAGLAVVADSFAALQTQVVERKRIA 497

Query: 547 ----------PIRDEDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKI---QKLH 593
                       R+E+G  I   +    P+FG+     D+ AV L   F +     ++  
Sbjct: 498 WKECVEAVRSDFRNENGEQIR-RLLASSPRFGHGGTCADEWAVTLTHDFAETFPNGRRTP 556

Query: 594 TYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVA 653
             R  IP   + +    + +GK  G TP+GRRAG P   GANP  G  + GA  ++    
Sbjct: 557 EGRLIIP--GLFSWADTLRFGKTVGATPNGRRAGEPSSHGANPCPGFRKDGAATAVAKAV 614

Query: 654 KLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNR 713
                   +       +  + +   D V +  L  L   +F       GG  +NVN+++ 
Sbjct: 615 ASVQCGYGNTSPLQLELDASFVNCADPVGR--LTALFRTHFKL-----GGTLINVNIVDA 667

Query: 714 EMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQ 758
           + L  A + PEK+P L +RV+G+   F  L+ E +  V+ R   +
Sbjct: 668 KTLRAAQKEPEKFPDLIVRVTGFTSYFIMLSPEFRDFVVKRIIEE 712


>UniRef50_C0VY69 Putative uncharacterized protein n=1 Tax=Actinomyces coleocanis DSM
           15436 RepID=C0VY69_9ACTO
          Length = 121

 Score = 90.1 bits (222), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 40/61 (65%), Positives = 50/61 (81%)

Query: 700 IEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQS 759
           ++G  H N+NV+N++ L+DAMENPEKYPQLT+RVSGYAV F  LT+EQQ DVI+RTF   
Sbjct: 61  VKGLYHANINVLNKDTLVDAMENPEKYPQLTVRVSGYAVNFVRLTREQQLDVISRTFHDG 120

Query: 760 M 760
           M
Sbjct: 121 M 121


>UniRef50_A7VPJ9 Putative uncharacterized protein n=1 Tax=Clostridium leptum DSM 753
           RepID=A7VPJ9_9CLOT
          Length = 725

 Score = 89.0 bits (219), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 147/629 (23%), Positives = 252/629 (40%), Gaps = 76/629 (12%)

Query: 174 GRGRIIGDYRRVALYGIDYL---MKDKLAQFTSLQAD-LENGVNLEQTIRLREEIAEQH- 228
            RG I  D+ ++   G + L    ++ L     L+A+    GV +   +   E+  +QH 
Sbjct: 120 ARGHITWDWTKILRLGTEGLKAQYENALHSAKDLEAEHFYRGVLI--ALEALEDWNDQHV 177

Query: 229 ---RALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLD 285
              R +G+ +E+A    +    PA   +EAIQ  +  YLA            G+   +L 
Sbjct: 178 AYLRKMGK-QELADLCQHVPRHPARGFKEAIQSFFMQYLAVFYENPFGGNGPGQFDKYLW 236

Query: 286 VYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESI-GGMGL 344
            Y+++DL+ G  T +EA+E+V+ L ++L           DE  S + +W    I GG   
Sbjct: 237 PYLKKDLENGSCTLEEAEELVEELFIRL-----------DERVSANDLWNEMIITGGTHR 285

Query: 345 DGRTLVTK------NSFRFLN----TLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSID 394
           DG + V+       ++   LN    T+Y   P       +    K  L +    A++  D
Sbjct: 286 DGSSAVSPLSKIMVDAIMKLNITHPTVYMRVPKDADEEYVKLCAKY-LKYGNNRAQIYYD 344

Query: 395 TSSLQYEND-DLMRPDFNNDDYAIACCVSPMIVGKQMQFF-GARANLAKTMLYAINGGVD 452
            + ++   + D +RP+ +  +Y +  C+   I G        A  N+   +  AI GG  
Sbjct: 345 PNVIRALTETDGVRPE-DATEYGVGGCLEIGIQGMNDDLLQCAWVNMPLMLELAITGGYS 403

Query: 453 EKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNII--HYMHDKYSYEAS 510
              + QV     P+ G +  ++       +++D+  +    + ++I    +HD+    A 
Sbjct: 404 LSERKQVDSAGIPLPG-LAQHNTFESFYKNYLDFTDRLVGISFSMIERQSIHDEKYRPAY 462

Query: 511 LMALHDRDVI---RTMACGIA----------GLSVAADSLSAIKYAKVKP---IRDEDGL 554
           L++    D +   R M  G A          G+    D L AI+ A         +E   
Sbjct: 463 LISSMIDDCLERGRHMHAGGARYHDYSMTPLGIPNVIDGLYAIRTAVFDQHICTAEELVS 522

Query: 555 AIDFEIEG---------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVL 605
           A+  + +G           P++G  +   DD A  +V    K           I    VL
Sbjct: 523 AMRADFKGYERLQRQLRAIPKYGQENDDADDFARTVVTDIAKMFVTRRNRFGGIFRPMVL 582

Query: 606 TITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGIS 665
           T     +   + G T DG         G  P       G  A++ S  K+PF Y   G S
Sbjct: 583 TFIYAPLAAAQLGATADGNNMHTMVAQGLTPQSRSMSCGITAAMNSCTKMPFYYFSGGAS 642

Query: 666 YTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEK 725
             + + P+         +  +A L+  +FH+     G Q    N  + + L++A ++PE 
Sbjct: 643 TMWDLDPHW------ASEKLIADLLMTFFHN-----GAQVFQGNTTDVKELIEAQKHPED 691

Query: 726 YPQLTIRVSGYAVRFNSLTKEQQQDVITR 754
           Y  L +RV G++ RF  LT   Q D+I R
Sbjct: 692 YEHLIVRVGGFSARFVGLTPGLQTDIINR 720


>UniRef50_C5EHI0 Pyruvate formate-lyase n=8 Tax=Bacteria RepID=C5EHI0_9FIRM
          Length = 703

 Score = 86.7 bits (213), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 130/563 (23%), Positives = 222/563 (39%), Gaps = 90/563 (15%)

Query: 236 EMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAG 295
           EMA  +G+          EA+Q+    +     S N    +FGR   ++  Y + D+++G
Sbjct: 182 EMARVFGHIPKQRPGTFMEALQFLRLLHYCLWCSFN-YHNTFGRFDQYMYPYYKADMESG 240

Query: 296 KITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSF 355
           ++T++EA E+++   +       L    Y  +  GD    +  +GG+  DG      +SF
Sbjct: 241 RLTKEEALELLEEFFISCNKDSDL----YPGMQQGDN-GQSMVLGGLNPDG-----SDSF 290

Query: 356 RFLNTLYTMGPSP----EPNMTILWSEKLPLNFKKFAAKVSIDTSSL---QYENDDLMRP 408
             L+ L           +P + +  ++  PL   ++     +    L   QY NDD++ P
Sbjct: 291 NELSDLCLQASLELKLIDPKINLRVNKDTPL--ARYERGTQLTRQGLGFPQYANDDVVIP 348

Query: 409 DFNN--------DDYAIACCVSPMIVGKQMQFFGARA-NLAKTMLYAINGGVDEKLKMQV 459
              +         DY +A C   +I G  M        + A  +L               
Sbjct: 349 CLRHWGYAEKDAYDYVVAACWEFIIPGTGMDIPNVNGLSFAAVVL--------------- 393

Query: 460 GPKSEPIKGDVLNYDEVMERMDHFMDWLAKQ-YITALNIIHYMHDKYSYEASLMAL---- 514
                    DVL+        + FMD +  + +  A  +   +H+ Y   A LM+L    
Sbjct: 394 ---------DVLDSLPGCGTFEAFMDKVKGEIFRMAGELCDSVHNVYMEPAPLMSLMMDG 444

Query: 515 ---HDRDVIR-----TMACGIAGLSVAADSLSAIK---YAKVKPIRDEDGLAIDFEIEG- 562
                RD+ +            GLS A DSL+AI+   Y       +E    +D + +G 
Sbjct: 445 CVERARDISKGNLYNNYGFHGTGLSTAVDSLAAIRKYVYEDRMFTAEELLKMLDADFKGY 504

Query: 563 ---------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVY 613
                    + P+ GN+D RVD+LA  L++ F   ++  +     I      +    V +
Sbjct: 505 EDIQNMLRYQSPKMGNDDDRVDELATRLLDWFADSLEGRNNDMGGIFRAGTGSAMYYVWH 564

Query: 614 GKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPN 673
            +    TPDGR  G       +P      +G V+ + S +K       +G   T  +  +
Sbjct: 565 SRNQHPTPDGRNEGEELACNYSPSLFTRLEGPVSIIKSFSKPHLERVANGGPLTIELHDS 624

Query: 674 ALGKDDEVRKTNL--AGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTI 731
               +D +RK  +     MD          GG  + +N +NRE +LDA E+PE +  L +
Sbjct: 625 MFRNEDSIRKVAVFVKSFMD---------MGGHQMQINAVNRETMLDAKEHPENHKNLIV 675

Query: 732 RVSGYAVRFNSLTKEQQQDVITR 754
           RV G++  F  L +  Q  +I R
Sbjct: 676 RVWGWSGYFVELDEVYQNQIIKR 698


>UniRef50_B0CLU5 Alpha-subunit of naphtylmethylsuccinate synthase n=4 Tax=Bacteria
           RepID=B0CLU5_9DELT
          Length = 828

 Score = 85.9 bits (211), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 106/440 (24%), Positives = 185/440 (42%), Gaps = 65/440 (14%)

Query: 367 SPEPNMTILWSEKLP-----LNFKKFAAKVSIDTSSLQYENDDLMR-----PDFNNDDYA 416
           +PEP++   +S K+      L F+  AA     +   + +N   M      P      +A
Sbjct: 404 TPEPSLGFRYSPKINAKTRRLVFENIAAGFGFPSIKHEEKNTRQMLEHYKVPPDEAAHWA 463

Query: 417 IACCVSPMI-----VGKQMQFFGARANLAKTMLYAINGGVDEKL-KMQVGPKSEPIKGDV 470
           +  C++P +     + K     G    + K    A   G D     +Q GPK+    GD 
Sbjct: 464 LVLCMAPGVSKRRGLQKTRTEGGGLIWIDKCCEIAFYDGFDHSFANIQTGPKT----GDA 519

Query: 471 LNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIR----TMACG 526
             +    E  + F   +  ++ TAL   HY +   +  A +  +    V       M  G
Sbjct: 520 TKFKTFEELFEAFEKQV--EFATAL---HYRNKDVTRRAEIKFIESPFVASLDDACMDDG 574

Query: 527 IA---------------GLSVAADSLSAIK---YAKVKPIRDEDGLAIDFEIEG------ 562
           +                G   AADSL+A+K   +   K   +E   A+    +G      
Sbjct: 575 VGAFVDKTYPNPWNNTPGEQTAADSLAAVKKLVFDDKKYTMEEVVNAMKANFDGYEEMRK 634

Query: 563 ---EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGN 619
                P++GN+DP VD++   + +    K+ +  TY    P  +  T+++      + G 
Sbjct: 635 DMLAAPKWGNDDPYVDEIGERVFKMVADKLMEQTTYSGMHPLGNPQTVSTFATRAPRIGA 694

Query: 620 TPDGRRAGAPFGPG-ANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKD 678
            P G+  G     G ++P  G D+KG  A L SVA +P+   K G+ +    +P ++ + 
Sbjct: 695 LPFGKLHGEVLHDGGSSPYVGLDKKGPTAVLKSVAHIPYDRYK-GVQFN-QRLPVSIMRG 752

Query: 679 DEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAV 738
           D+  +   +  M  +  H+ +I+   H+  NV+  + +L+A + PEK+  L +R++GY+ 
Sbjct: 753 DKGFQV-WSAYMKAW--HDLNID---HVQFNVVETKDMLEAQKEPEKWESLIVRIAGYSA 806

Query: 739 RFNSLTKEQQQDVITRTFTQ 758
           RF SL K  Q  +I R   Q
Sbjct: 807 RFVSLPKNAQDAIIARNEQQ 826


>UniRef50_C0A3H6 Formate C-acetyltransferase n=1 Tax=Opitutaceae bacterium TAV2
           RepID=C0A3H6_9BACT
          Length = 765

 Score = 78.6 bits (192), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 62/252 (24%), Positives = 116/252 (46%), Gaps = 33/252 (13%)

Query: 528 AGLSVAADSLSAIKYAKVKPIRDEDGLA---IDFEIEGEYPQFG--------NNDPRVDD 576
           AG++V ADS +A++    + + DE  L    +++ IE  +P            +  R   
Sbjct: 523 AGIAVVADSFAALE----QRVADEGCLTWAEVNWHIEKNFPDIEGERVRLMLQSSERYGQ 578

Query: 577 LAVDLVERFMKKIQKLHT---------YRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAG 627
              +  ER+  +I    +         Y D      + +  + + +G+    TP+GRRAG
Sbjct: 579 ATGNRAERWAVRITGTWSGMVRDQNRRYPDYNFIPGLFSWANTIEFGEAVSATPNGRRAG 638

Query: 628 APFGPGANPMHGRDQKGAVASLT-SVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNL 686
            P   GANP+ G  + GAV +L  ++A +   Y          + P+     + + K  +
Sbjct: 639 QPINHGANPLPGFRKDGAVTALVNAIAAVQPGYGNTA-PVQLELDPSIAESPEAIEK--I 695

Query: 687 AGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKE 746
             L+   F      +G   LN+N+++ E +L+A ++P K+P L +RV+G+   F  L+ +
Sbjct: 696 TALIKTMFD-----QGCTLLNINLIDEERVLEAHKDPSKFPDLIVRVTGFTSYFAMLSPQ 750

Query: 747 QQQDVITRTFTQ 758
            +Q V+ R  ++
Sbjct: 751 FRQLVVDRILSR 762


>UniRef50_A7VW43 Putative uncharacterized protein n=1 Tax=Clostridium leptum DSM 753
           RepID=A7VW43_9CLOT
          Length = 737

 Score = 76.6 bits (187), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 68/253 (26%), Positives = 118/253 (46%), Gaps = 30/253 (11%)

Query: 520 IRTMACGIAGLSVAADSLSAIKYAKVKPIRD-----EDGLAIDF----------EIEGEY 564
           I T+ C   GL   ADS +AI+   V+  +      E+ L  +F               Y
Sbjct: 492 IYTLCCDGVGLGTLADSFAAIEQRIVREKKLTFEELEETLRNNFAGDERTRLMLSQSERY 551

Query: 565 PQFGNN--DPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPD 622
            Q G++  D     L  D  E  + K Q +   +  +P     + +  + +G++ G TP+
Sbjct: 552 CQGGDSLGDQWAQRLTRDFAE--IVKAQPVAGGKQLVP--GWFSWSKTIHFGRQVGATPN 607

Query: 623 GRRAGAPFGPGANPMHG-RDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEV 681
           GR+AGA    GANP  G R    A A  T +A     Y   G +    I  +     +E 
Sbjct: 608 GRKAGASVTHGANPTPGFRKDGAATAQATGIALCQPGY---GNTAPLQIEFDPKLSAEEG 664

Query: 682 RKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFN 741
               +A L+  +        GG  +NVNV+++++L++A ++P+ +P+L +RV+G+   F 
Sbjct: 665 GIDRVAKLLKTHIDM-----GGTLINVNVLDKDVLMEAHKDPKSHPELVVRVTGFTAYFC 719

Query: 742 SLTKEQQQDVITR 754
           +L+++ +Q V+ R
Sbjct: 720 TLSEDFRQLVVDR 732


>UniRef50_C6IIV1 Formate acetyltransferase 2 n=3 Tax=Bacteria RepID=C6IIV1_9BACE
          Length = 714

 Score = 75.1 bits (183), Expect = 9e-12,   Method: Compositional matrix adjust.
 Identities = 71/258 (27%), Positives = 121/258 (46%), Gaps = 39/258 (15%)

Query: 522 TMACGIAGLSVAADSLSAIKYAKVKPIRDEDGLAIDFEIEGEYPQF-GNNDPRVDDL--- 577
            +A   AGL+  ADS +A++    + I  E+ L+ +   E     F G+   R+  L   
Sbjct: 471 NLAIDGAGLATVADSFAALE----QRIELENKLSWNTLTEYLRNNFSGDGGCRIRHLLKN 526

Query: 578 ------AVDLVERFMKKIQKLHTYRDAIPTQS-----------VLTITSNVVYGKKTGNT 620
                 A  L E++  +I++  T+ + +  QS             +  + V +G+  G T
Sbjct: 527 SEKYGAAESLGEKWAIRIKE--TFTELVRLQSEPDKRRIFIPGFFSWANTVGFGQSVGAT 584

Query: 621 PDGRRAGAPFGPGANPMHGRDQKGAVASL-TSVAKLPFAYAKDGISYTFSIVPNALGKDD 679
           PDGR A  P   GANP  G  + GA  SL T +AK+   Y        + + P     D+
Sbjct: 585 PDGRLAQTPISHGANPTPGFVKDGASLSLATIIAKIQPGYGNTA-PMQWELDPTFANMDN 643

Query: 680 -EVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAV 738
            E+    +  ++  +F       GG  +NVN+MN++ +L A ++P  YP+L +RV+G+  
Sbjct: 644 IEL----IMSIIRAHFDL-----GGTLINVNIMNKDTVLAAHKDPAGYPELVVRVTGFTA 694

Query: 739 RFNSLTKEQQQDVITRTF 756
            F+ L+ + +Q V+ R  
Sbjct: 695 YFSMLSPQFRQLVVDRIL 712


>UniRef50_D1N5W4 Formate C-acetyltransferase n=1 Tax=Victivallis vadensis ATCC
           BAA-548 RepID=D1N5W4_9BACT
          Length = 783

 Score = 73.9 bits (180), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 115/477 (24%), Positives = 179/477 (37%), Gaps = 67/477 (14%)

Query: 334 WATES---IGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILW----SEKLPLNFKK 386
           WA      +GG  L G  L    +   L   +     P+P +++       E+L  N  +
Sbjct: 311 WAISQNLLLGGRDLAGNDLGCGMTDVILEAFFRSN-QPQPALSVKIHRNSPERLFRNMGR 369

Query: 387 FAAKVSIDTSSLQYENDDLMR--------PDFNNDDYAIACCVSPMIVGKQM-QFFGARA 437
           F       T SL   NDD+M          D +  D+A+A C  P+I+GK+      +  
Sbjct: 370 FYFTPGHSTPSLF--NDDMMFRVLKSKGIADADIPDWAVAGCQEPLIMGKENGNTTNSWL 427

Query: 438 NLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDE-----------VMERMDH---F 483
           NLAK +   +N G       ++G     +    L YD               ++DH   F
Sbjct: 428 NLAKVLELVLNDGCSLLTGRRIG-----LSAAELGYDSPEAAYRDLETAFFRQLDHVLPF 482

Query: 484 MDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRT------MACGIAGLSVAADSL 537
           M+  A +   A+           +         RD  R         C I GL V ADSL
Sbjct: 483 MEAAANRCTRAIGGWATPFGSLLFGGLESGRDMRDPERPGTRYSGSGCLIHGLGVVADSL 542

Query: 538 SAIKYAKVKPIRDEDGL------------AIDFEIEGEYPQFGNNDPRVDDLAVDLVERF 585
            A+K+   +     D L            A+   +   YP++G+  P  D+ A  +    
Sbjct: 543 VAVKHFLAEQPGGADSLRAALRNNFADAPALRARLLA-YPKYGSVLPEPDETAARIASVV 601

Query: 586 MKKIQKLHTY--RDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQK 643
             K+  L     R  +P  S  T +++++YG   G TPDGR A A  G G +P       
Sbjct: 602 SDKVYALRNPAGRPFMPDFS--TPSTHLLYGYWVGATPDGRPARAMLGYGVDPRPEVTNS 659

Query: 644 GAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLA---GLMDGYFHHEASI 700
                L S   LPF     G +    + P A     E+ +  +A    ++   F   A  
Sbjct: 660 ELTDQLLSERGLPFGKMVGGYASHIGLAPAAFADRAELEEKGVAMRDRVIRPLFAAGAEG 719

Query: 701 EGGQHLNVNVMNREMLLDAMENPEKYPQLTI---RVSGYAVRFNSLTKEQQQDVITR 754
           E   ++  N+ + + L   + +P +Y    I   R+ G  V F  L    Q+D+I R
Sbjct: 720 EAPYYVYFNIDSAKHLRKILTDPARYVPSGIYIMRIHGTFVNFLDLAPAIQEDIIKR 776


>UniRef50_D1N9D9 Formate C-acetyltransferase n=1 Tax=Victivallis vadensis ATCC
           BAA-548 RepID=D1N9D9_9BACT
          Length = 748

 Score = 72.4 bits (176), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 50/165 (30%), Positives = 76/165 (46%), Gaps = 25/165 (15%)

Query: 592 LHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTS 651
           L++YRD I             + K T  TPDGRRAG     G  P   R    AV  + S
Sbjct: 606 LYSYRDIID------------WAKVTRATPDGRRAGDFLSQGLTP--ARTHADAVTQVFS 651

Query: 652 -VAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNV 710
             A LP          T S+  N L +           L+ G+      + G   L +N 
Sbjct: 652 DTASLPLLRFPANSVLTLSLSKNGLTE----------ALLSGFLKAWVLVRGSGMLQLNC 701

Query: 711 MNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRT 755
           ++RE L DA +NP+ +  L +R+ GY+ +F +L++E+Q++ I+R 
Sbjct: 702 ISREELEDAQKNPQNHASLIVRLYGYSAKFITLSEEKQREFISRN 746


>UniRef50_B2V300 4-hydroxyphenylacetate decarboxylase, catalytic subunit n=12
           Tax=Bacteria RepID=B2V300_CLOBA
          Length = 905

 Score = 70.5 bits (171), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 51/192 (26%), Positives = 89/192 (46%), Gaps = 9/192 (4%)

Query: 565 PQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGR 624
           P++GN+DP VD +  D  + F        +          ++++++   G  T  T DGR
Sbjct: 717 PKYGNDDPYVDSILKDYEDWFCDVCHNYESLYGKKMYACQISVSTHGAQGAATLATTDGR 776

Query: 625 RAGAPFGPGANPMH-GRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRK 683
            AG  +  G+   + G D+ G  A  TS      + +++       I P+A+   +  +K
Sbjct: 777 LAGTTYADGSMSAYPGTDKNGPYALFTSATVWDHSKSQNS-QMNLKIHPSAIKGIEGSKK 835

Query: 684 TNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSL 743
             L  L   Y       +GG H+  NV++ ++L +A   PE Y  L +RV+G+   +  +
Sbjct: 836 --LLDLTRSYMR-----KGGYHIQYNVVDSKVLKEAQVKPESYRDLMVRVAGFTQYWCEI 888

Query: 744 TKEQQQDVITRT 755
            K  Q +VI+RT
Sbjct: 889 GKPIQDEVISRT 900



 Score = 45.4 bits (106), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 34/133 (25%), Positives = 69/133 (51%), Gaps = 3/133 (2%)

Query: 253 QEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMK 312
           +EA+Q TY  ++A +     + +S GR    L  + ++D++ G+ITE+E  E+++   +K
Sbjct: 331 REALQLTYIIHIAVINEDAISGLSPGRVGQVLYPWFKQDIENGRITEKEVLELLELHRVK 390

Query: 313 LRMVR-FLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPN 371
              +  F  T     + SG+  +   ++GG+  DG +   +  +  +    T   +P+P 
Sbjct: 391 FTCIDCFASTGVVGGVLSGN-TFNNLTLGGLKKDGSSAANRLEYLIVEAGITCA-TPQPT 448

Query: 372 MTILWSEKLPLNF 384
           ++  + EKLP +F
Sbjct: 449 LSCFYDEKLPEDF 461


>UniRef50_A5ZSK3 Putative uncharacterized protein n=1 Tax=Ruminococcus obeum ATCC
           29174 RepID=A5ZSK3_9FIRM
          Length = 745

 Score = 67.0 bits (162), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 124/570 (21%), Positives = 220/570 (38%), Gaps = 54/570 (9%)

Query: 220 LREEIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGR 279
           L+ E  E+H  +  +K +A       S PA    EA+   +F                G 
Sbjct: 194 LKTEHDEEH--VKALKMIAVTARRIPSEPAETFYEAMCAIWFTREMCNALDGLGFAVIGH 251

Query: 280 TSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESI 339
               L  Y ERDLK  +IT  EAQE++D  V  +   R+    +     + D I     I
Sbjct: 252 LDRILISYYERDLKNNRITPDEAQELIDCFV-SMTDARWNLEADLPGGTNADII-----I 305

Query: 340 GGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVS-IDTSSL 398
           GG   +G  +    S   +N+ Y       P + +  S K P  F     +++ +  + L
Sbjct: 306 GGCDKNGDIVYNDISRMIINS-YKKYHFANPKLQVRISAKHPDEFLLQVGELAGMGLNVL 364

Query: 399 QYENDDLMRPDFNNDDYAIACCVSPMIVGKQMQFFG----ARANLAKTMLYAINGG---- 450
              NDD++ P       ++  C   +  G Q         +RA     ++  +NG     
Sbjct: 365 SIFNDDVIIPANQKQGKSLEDCRLYVAGGCQEICLSNEVNSRAYTYLNLVQMLNGSLYPE 424

Query: 451 ----VDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYS 506
               + ++   +  P +     +   Y  V+E   + +++  K+Y    +    ++    
Sbjct: 425 YWNDIFKRDGFEFLPAANASDFEEF-YHIVIENYRNELNFFVKKYNEYGSWWKIINPSLF 483

Query: 507 YEASLMALHD--RDVIRTMAC------GIAGLSVAADSLSAIKYAKVKPIRDEDGLAI-- 556
           + A++ +  +  +DV    A         AG     DSL AIK A  +      G  +  
Sbjct: 484 FSATMPSCTETAKDVSEGGAVYNTDNFAAAGAGTVIDSLYAIKKAVYEDKITTFGHLLKA 543

Query: 557 ------DFEIEGEY-----PQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVL 605
                 D EI  +Y     P+F   D    +    +++   + +     YR      S+ 
Sbjct: 544 MKEDFRDDEILRQYLLHKVPKFCK-DKDATEFGKKVMDDLAECLGGQANYRGGKFEPSLF 602

Query: 606 TITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGIS 665
              S   +   T  T DGR++ +    G NP    +     A L ++  + +     G +
Sbjct: 603 AFYSYNWFKNVTIATADGRKSESALSRGVNPSESTENINIAALLDAIKTMDYTKYPGG-A 661

Query: 666 YTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEK 725
             +  +P         + +  A +M  +  +     GG  ++ NV++R  LL+A +NPE 
Sbjct: 662 VIYMDIPLMYKTP---QPSLFASVMRAFCEN-----GGSIMDFNVISRNALLEAQKNPET 713

Query: 726 YPQLTIRVSGYAVRFNSLTKEQQQDVITRT 755
           +  + +RV GY+  F++LT E Q +VI RT
Sbjct: 714 HKNIVVRVCGYSAYFHTLTAEMQNEVIQRT 743


>UniRef50_C7XCZ5 Formate acetyltransferase 2 n=2 Tax=Bacteria RepID=C7XCZ5_9PORP
          Length = 670

 Score = 67.0 bits (162), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 55/189 (29%), Positives = 83/189 (43%), Gaps = 13/189 (6%)

Query: 566 QFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRR 625
           +FG  D  V  L+ +L+    + I KL    +    +  L+  S +  GK    T DGR 
Sbjct: 488 KFGLCDEYVLRLSQELIGTVSETIGKLTA--NGYNVKFGLSSPSYISRGKVASATLDGRN 545

Query: 626 AGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTN 685
           AG PF    +P+        V    S    P     +G    + I P  L   D+     
Sbjct: 546 AGEPFAVHISPLSSTIDIAEVLDFASSLSYPVN-CLNGNVVDYVIPPVYLNNSDK----- 599

Query: 686 LAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTK 745
           L  ++   F      +G   L +NV +R  L+DA  +PEKYP L +RV G++  FN L +
Sbjct: 600 LVPILRDAFK-----KGLYQLQLNVYDRATLIDAKLHPEKYPTLVVRVWGFSAYFNDLPE 654

Query: 746 EQQQDVITR 754
           E + ++I R
Sbjct: 655 EYKDNLIAR 663


>UniRef50_O26446 Formate acetyltransferase 2 n=1 Tax=Methanothermobacter
           thermautotrophicus str. Delta H RepID=O26446_METTH
          Length = 642

 Score = 62.0 bits (149), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 51/196 (26%), Positives = 83/196 (42%), Gaps = 19/196 (9%)

Query: 565 PQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGR 624
           P +G ++  V +L   +++    K+   + +  + P    L        G+ TG + DGR
Sbjct: 458 PGYGMDEDEVVELTNTIIQMLHDKLGGRYKFGLSSPVYITL--------GESTGASFDGR 509

Query: 625 RAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGK-DDEVRK 683
            AG P G   +P+   D       L   A L +  A +G      +    L +  +E   
Sbjct: 510 HAGEPLGVHISPLKFTDGMSYTEVLNFAAALDYLKAFNGGVVDIMVDRPFLDRAGNEFMA 569

Query: 684 TNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSL 743
               GL  G             L VNV++ E+LL A +NPE YP L +RV G++  F  L
Sbjct: 570 LIRTGLRRGVMQ----------LQVNVLDPEVLLRARDNPELYPDLIVRVWGFSAYFRDL 619

Query: 744 TKEQQQDVITRTFTQS 759
            +E ++ ++ R    S
Sbjct: 620 PEEYRELIVRRALEYS 635


>UniRef50_Q38HX4 4-hydroxyphenylacetate decarboxylase glycyl radical subunit n=3
           Tax=Clostridiales RepID=Q38HX4_9CLOT
          Length = 897

 Score = 60.1 bits (144), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 50/192 (26%), Positives = 84/192 (43%), Gaps = 9/192 (4%)

Query: 565 PQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGR 624
           P++GN D   D++             K  +Y         ++++++   G  T  T DGR
Sbjct: 710 PKYGNADKYADEIFKAYHYYIYDMTHKFRSYYGKPLYLCQISVSTHGPQGFVTLATADGR 769

Query: 625 RAGAPFGPGA-NPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRK 683
            AG  +  G+ +   G D+ G  A   S      +  ++       + P A+   +  RK
Sbjct: 770 LAGTTYSDGSVSAAAGTDKNGIYAIFESATVYDHSMHQNA-QMNLKLHPTAVKGINGTRK 828

Query: 684 TNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSL 743
             L  L+  Y       +GG H+  NV++ + L DA   PEKY +L +RV+G+   +  +
Sbjct: 829 --LLDLVRAYMR-----KGGFHVQFNVVDSKTLRDAQLTPEKYRELMVRVAGFTQYWCEI 881

Query: 744 TKEQQQDVITRT 755
            K  Q +VI RT
Sbjct: 882 GKPIQDEVIYRT 893



 Score = 52.8 bits (125), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 37/143 (25%), Positives = 68/143 (47%), Gaps = 3/143 (2%)

Query: 251 NAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLV 310
           N  EAIQ T   +   V     + +S GR    L  + E+D++ G +T++E  E+++   
Sbjct: 322 NFWEAIQMTLCCHFGVVNEDPQSGLSIGRLGQVLQPFYEKDVEDGIMTDEEVIELLELYR 381

Query: 311 MKLRMVR-FLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPE 369
           +K+  +  F        + SG+  +   S+GG   DG + VT   +  +        +P+
Sbjct: 382 IKITCIECFASAGVSGGVLSGN-TFNNLSLGGQNYDGLSAVTPLEYLIVEAG-MRNQTPQ 439

Query: 370 PNMTILWSEKLPLNFKKFAAKVS 392
           P +++L+ EK P +F   AA  +
Sbjct: 440 PTLSVLYDEKTPEDFLMKAASCT 462


>UniRef50_Q4C1X2 Putative uncharacterized protein n=1 Tax=Crocosphaera watsonii WH
           8501 RepID=Q4C1X2_CROWT
          Length = 99

 Score = 54.7 bits (130), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 23/46 (50%), Positives = 32/46 (69%)

Query: 553 GLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDA 598
           GLA+D+E+E +YP+FGNND R D +   ++  FM  I+K  TYR A
Sbjct: 5   GLAVDYEVEEDYPKFGNNDERADTITAKVLSDFMNNIRKNKTYRQA 50


>UniRef50_O94139 Formate C-acetyltransferase (Fragment) n=2 Tax=Piromyces sp. E2
           RepID=O94139_9FUNG
          Length = 140

 Score = 51.6 bits (122), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 28/62 (45%), Positives = 37/62 (59%)

Query: 21  QNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLWDKVMEGVKLENRTHAPVDFDTAVAS 80
           ++E++V  +I+K+YTPYEGD SFLAG TE T  L+ K  E +  E       D D    S
Sbjct: 79  KSEIDVEGWIKKHYTPYEGDGSFLAGPTEKTKKLFAKAEEYLAKERANGGLYDVDPHTPS 138

Query: 81  TI 82
           TI
Sbjct: 139 TI 140


>UniRef50_A5UFY3 Formate acetyltransferase n=1 Tax=Haemophilus influenzae PittGG
          RepID=A5UFY3_HAEIG
          Length = 36

 Score = 50.8 bits (120), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 23/32 (71%), Positives = 23/32 (71%)

Query: 1  MSELNEKLATAWEGFTKGDWQNEVNVRDFIQK 32
          MSELNE    AW GF  GDWQ  VNVRDFIQK
Sbjct: 1  MSELNEMQKLAWAGFAGGDWQENVNVRDFIQK 32


>UniRef50_UPI0001742832 Formate acetyltransferase n=1 Tax=candidate division TM7
          single-cell isolate TM7a RepID=UPI0001742832
          Length = 53

 Score = 48.1 bits (113), Expect = 0.001,   Method: Composition-based stats.
 Identities = 22/38 (57%), Positives = 28/38 (73%)

Query: 28 DFIQKNYTPYEGDESFLAGATEATTTLWDKVMEGVKLE 65
          +FI+ NYT Y GD+SFL G TEATT LW ++ E  K+E
Sbjct: 1  EFIRLNYTEYLGDDSFLEGPTEATTKLWKELSEKFKVE 38


>UniRef50_Q39VF1 Formate C-acetyltransferase glycine radical:Pyruvate formate-lyase,
           PFL n=87 Tax=Bacteria RepID=Q39VF1_GEOMG
          Length = 862

 Score = 47.4 bits (111), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 128/573 (22%), Positives = 216/573 (37%), Gaps = 92/573 (16%)

Query: 248 PATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGK---ITEQEAQE 304
           P    ++A Q  ++ YL        A+    +    L+ Y    +K      +T  +  E
Sbjct: 299 PCKGLKDAFQAKWYTYLICHAIDRYASGYAQKEDEMLEPYYNISVKEKSFQPMTHTDVVE 358

Query: 305 MVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMG---LDGRTLVTKNSFRFLNTL 361
           MV+   +K+      ++  Y E+F G       +IGG     +D  + +T         +
Sbjct: 359 MVEMERLKISEHGAGKSRAYREIFPGSNDLFILTIGGTKPGYVDACSDMTDAILEGARNI 418

Query: 362 YTMGPSPEPNMTILWS----EKLP----------LNFKKFAAKVSIDTSSLQYENDDLMR 407
            T     EP++   W     EK            L +      V I T  L+Y +     
Sbjct: 419 RTT----EPSIVFRWHPVGREKTKRLVFECIRDGLGYPSIKHDV-IGTEQLKYYSQFSKN 473

Query: 408 PDFNNDD----YAIACCVSPMIVGKQMQFF-----GARANLAKTMLYAINGGVDEKLK-M 457
            +   DD    + +  C+SP + G++         G     AK M   +  G D     M
Sbjct: 474 NNGATDDEAHYWGLVLCMSPGVCGRRKTHKTRSEGGGSIFPAKMMEIVLADGFDWSYSGM 533

Query: 458 QVGPKSEPIKGDVLNYDEVMERMDHFMDWLA---KQYITALNIIHYMHDKYSYEASLMAL 514
           Q+GP +    GD   +    +  + F    A    + I A +I+ Y   K+     + ++
Sbjct: 534 QLGPHT----GDPTTFKTFEQLWEAFRSQYAYATSKVIRAKDIMRYYESKFLQMPFVSSI 589

Query: 515 HDRDVIRTMACGIAGLS---------------VAADSLSAIK---YAKVKPIRDEDGLAI 556
            D      M  GI  +                VAA+SL AIK   Y + K    +   A+
Sbjct: 590 DDG----CMELGIDSMELSEQPNGWHNPITTVVAANSLVAIKKLIYDEKKYTMAQLVTAL 645

Query: 557 DFEIEG---------EYPQFGNNDPRVDDLAVDLVERFMK-KIQKLHTYR--DAIPTQSV 604
                G           P++GN+D   D +     E  +  ++ K+  Y     +P    
Sbjct: 646 RANWHGYEDMRQDFLNAPKWGNDDEYADTIIKKFYEDIIGGEMAKITNYSGGPVLPVGQA 705

Query: 605 LTITSNVVYGKKTGNTPDGRRAGAPFGPGA-NPMHGRDQKGAVASLTSVAKLPFAYAKDG 663
           + +   +  G +TG TPDGR  G     G  +P  G D+KG  A L SV+K+      + 
Sbjct: 706 VGLYMEI--GSRTGPTPDGRFGGDAGDDGGISPYMGTDKKGPTAVLKSVSKVQKNQKANL 763

Query: 664 ISYTFS--IVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAME 721
           ++   S  I+ +  G       T     MD +   + +I+   H+  N ++   +  A +
Sbjct: 764 LNQRLSVPIMRSVHGF------TIWKSYMDAW--EKLNID---HVQFNCVSTAEMKAAQK 812

Query: 722 NPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITR 754
            PEK+  L +RVSG++ RF  +    Q  +I R
Sbjct: 813 EPEKHQDLIVRVSGFSARFVDIPTYGQNTIIAR 845


>UniRef50_A6BGV7 Putative uncharacterized protein n=1 Tax=Dorea longicatena DSM
           13814 RepID=A6BGV7_9FIRM
          Length = 121

 Score = 46.6 bits (109), Expect = 0.004,   Method: Composition-based stats.
 Identities = 27/93 (29%), Positives = 41/93 (44%), Gaps = 2/93 (2%)

Query: 591 KLHTYRDAIPTQS--VLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVAS 648
           ++ +YR    T +  +L ++ N   G + G  P GR A  P   G +P  G D +G  A 
Sbjct: 8   EIESYRSKFGTMTPGILPVSGNTPVGLEVGALPSGRHAWKPLADGVSPNGGTDTEGPGAV 67

Query: 649 LTSVAKLPFAYAKDGISYTFSIVPNALGKDDEV 681
           L SV+ LP      G      I P  L  ++ +
Sbjct: 68  LKSVSHLPHDRFVQGTFLNMKIEPEILNSENGI 100


>UniRef50_D2T6G2 Autonomous glycyl radical cofactor n=1 Tax=Erwinia pyrifoliae DSM
           12163 RepID=D2T6G2_ERWPY
          Length = 85

 Score = 45.8 bits (107), Expect = 0.006,   Method: Composition-based stats.
 Identities = 19/35 (54%), Positives = 27/35 (77%)

Query: 700 IEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVS 734
           + GGQHLN N ++RE L + +++PE  PQLT+RVS
Sbjct: 39  VAGGQHLNANFLSREGLEEVVKHPEITPQLTLRVS 73


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_Q2G1D8 Formate acetyltransferase n=978 Tax=cellular org...   953   0.0  
UniRef50_B3DSM0 Pyruvate-formate lyase n=32 Tax=Bacteria RepID=B...   816   0.0  
UniRef50_B4U135 Pyruvate formate-lyase n=65 Tax=Bacilli RepID=B4...   741   0.0  
UniRef50_C1N297 Predicted protein n=1 Tax=Micromonas pusilla CCM...   734   0.0  
UniRef50_O32799 Formate acetyltransferase n=32 Tax=Bacilli RepID...   730   0.0  
UniRef50_A0Q2M5 Pyruvate formate-lyase n=9 Tax=Bacteria RepID=A0...   648   0.0  
UniRef50_B2TMN7 Formate C-acetyltransferase n=13 Tax=Bacteria Re...   635   e-180
UniRef50_B5I3J0 Truncated formate acetyltransferase n=8 Tax=Bact...   618   e-175
UniRef50_B1C5P6 Putative uncharacterized protein n=3 Tax=Bacteri...   604   e-171
UniRef50_P75793 Putative formate acetyltransferase 3 n=109 Tax=B...   604   e-171
UniRef50_C6VIV4 Formate C-acetyltransferase n=25 Tax=Bacteria Re...   595   e-168
UniRef50_B2TJX0 Formate C-acetyltransferase n=9 Tax=Bacteria Rep...   595   e-168
UniRef50_B2ISH7 Formate acetyltransferase, putative n=59 Tax=Bac...   594   e-168
UniRef50_A8GF53 Pyruvate formate-lyase n=31 Tax=Bacteria RepID=A...   591   e-167
UniRef50_A6LQ73 Pyruvate formate-lyase n=6 Tax=Bacteria RepID=A6...   588   e-166
UniRef50_O28823 Pyruvate formate-lyase 2 (PflD) n=1 Tax=Archaeog...   587   e-166
UniRef50_D1AFQ7 Pyruvate formate-lyase n=3 Tax=Fusobacteriaceae ...   586   e-166
UniRef50_C7X781 Pyruvate formate-lyase n=3 Tax=Bacteroidales Rep...   582   e-164
UniRef50_Q18AX8 Glycerol dehydratase n=8 Tax=Clostridium RepID=Q...   578   e-163
UniRef50_C6A251 Pyruvate-formate lyase n=50 Tax=cellular organis...   576   e-163
UniRef50_B6FJR9 Putative uncharacterized protein n=1 Tax=Clostri...   576   e-162
UniRef50_A5N4Z6 Predicted glycyl radical enzyme n=2 Tax=Clostrid...   576   e-162
UniRef50_B6FX97 Putative uncharacterized protein n=4 Tax=Firmicu...   571   e-161
UniRef50_B8G188 Pyruvate formate-lyase n=1 Tax=Desulfitobacteriu...   569   e-160
UniRef50_A6TPN1 Formate C-acetyltransferase n=3 Tax=Clostridiace...   566   e-160
UniRef50_P32674 Formate acetyltransferase 2 n=80 Tax=Gammaproteo...   566   e-160
UniRef50_C0W9F6 Formate C-acetyltransferase n=1 Tax=Acidaminococ...   564   e-159
UniRef50_B5XXR3 Formate C-acetyltransferase 2 n=9 Tax=cellular o...   562   e-158
UniRef50_A6TKL5 Pyruvate formate-lyase n=1 Tax=Alkaliphilus meta...   557   e-157
UniRef50_Q1A666 Glycerol dehydratase n=8 Tax=Clostridiales RepID...   549   e-154
UniRef50_C0QGR8 PflD1 n=1 Tax=Desulfobacterium autotrophicum HRM...   547   e-154
UniRef50_D1ARQ1 Pyruvate formate-lyase n=3 Tax=Bacteria RepID=D1...   540   e-151
UniRef50_C0C5J5 Putative uncharacterized protein n=1 Tax=Clostri...   536   e-151
UniRef50_C7N778 Pyruvate-formate lyase n=1 Tax=Slackia heliotrin...   531   e-149
UniRef50_B8FA81 Formate C-acetyltransferase n=1 Tax=Desulfatibac...   531   e-149
UniRef50_B0G487 Putative uncharacterized protein n=2 Tax=Clostri...   528   e-148
UniRef50_A8MJE8 Formate C-acetyltransferase n=57 Tax=Bacteria Re...   525   e-147
UniRef50_B8FFL2 Formate C-acetyltransferase n=1 Tax=Desulfatibac...   524   e-147
UniRef50_A8ZW07 Formate C-acetyltransferase n=2 Tax=Proteobacter...   522   e-146
UniRef50_Q312S2 Formate C-acetyltransferase n=9 Tax=Bacteria Rep...   521   e-146
UniRef50_B8J0R1 Formate C-acetyltransferase n=9 Tax=Proteobacter...   513   e-143
UniRef50_Q30WU7 Formate C-acetyltransferase n=1 Tax=Desulfovibri...   501   e-140
UniRef50_A6CWD5 Formate acetyltransferase 2 n=4 Tax=Bacteria Rep...   498   e-139
UniRef50_UPI00016BFDA6 pyruvate formate-lyase n=1 Tax=Epulopisci...   494   e-138
UniRef50_B8FDB2 Formate C-acetyltransferase n=1 Tax=Desulfatibac...   494   e-138
UniRef50_A6G8C6 Pyruvate formate-lyase 2 (PflD) n=1 Tax=Plesiocy...   470   e-130
UniRef50_B8FHW6 Formate C-acetyltransferase n=2 Tax=Desulfobacte...   468   e-130
UniRef50_D2LJ70 Formate C-acetyltransferase n=1 Tax=Rhodomicrobi...   466   e-129
UniRef50_A5CZF4 Pyruvate-formate lyase n=1 Tax=Pelotomaculum the...   466   e-129
UniRef50_C6BT93 Formate C-acetyltransferase n=6 Tax=Desulfovibri...   463   e-128
UniRef50_B1BA70 HpdB protein n=1 Tax=Clostridium botulinum C str...   454   e-126
UniRef50_B8FMK7 Formate C-acetyltransferase n=1 Tax=Desulfatibac...   448   e-124
UniRef50_B0MIH0 Putative uncharacterized protein n=1 Tax=Anaeros...   444   e-123
UniRef50_B8FEM4 Formate C-acetyltransferase n=5 Tax=Proteobacter...   438   e-121
UniRef50_Q38HX4 4-hydroxyphenylacetate decarboxylase glycyl radi...   412   e-113
UniRef50_A7VPJ9 Putative uncharacterized protein n=1 Tax=Clostri...   405   e-111
UniRef50_D1ANR4 Formate C-acetyltransferase n=1 Tax=Sebaldella t...   405   e-111
UniRef50_C5EHI0 Pyruvate formate-lyase n=8 Tax=Bacteria RepID=C5...   402   e-110
UniRef50_B0NGB8 Putative uncharacterized protein n=3 Tax=Bacteri...   397   e-109
UniRef50_B2V300 4-hydroxyphenylacetate decarboxylase, catalytic ...   394   e-108
UniRef50_B0CLU5 Alpha-subunit of naphtylmethylsuccinate synthase...   386   e-105
UniRef50_C0CUZ2 Putative uncharacterized protein n=1 Tax=Clostri...   377   e-102
UniRef50_Q2C4S5 Formate acetyltransferase n=7 Tax=Gammaproteobac...   373   e-101
UniRef50_A5ZSK3 Putative uncharacterized protein n=1 Tax=Ruminoc...   370   e-100
UniRef50_D1N5W4 Formate C-acetyltransferase n=1 Tax=Victivallis ...   369   e-100
UniRef50_D1N4L3 Formate C-acetyltransferase n=1 Tax=Victivallis ...   367   e-100
UniRef50_A9KN53 Pyruvate formate-lyase n=21 Tax=Bacteria RepID=A...   363   1e-98
UniRef50_D1NB06 Formate C-acetyltransferase n=1 Tax=Victivallis ...   359   3e-97
UniRef50_A6CVH9 Formate C-acetyltransferase n=10 Tax=Bacteria Re...   329   2e-88
UniRef50_A7VW43 Putative uncharacterized protein n=1 Tax=Clostri...   308   6e-82
UniRef50_O26446 Formate acetyltransferase 2 n=1 Tax=Methanotherm...   295   4e-78
UniRef50_C0A3H6 Formate C-acetyltransferase n=1 Tax=Opitutaceae ...   295   5e-78
UniRef50_C6IIV1 Formate acetyltransferase 2 n=3 Tax=Bacteria Rep...   295   5e-78
UniRef50_D1N9D9 Formate C-acetyltransferase n=1 Tax=Victivallis ...   292   4e-77
UniRef50_C7XCZ5 Formate acetyltransferase 2 n=2 Tax=Bacteria Rep...   275   5e-72
UniRef50_O94132 Formate C-acetyltransferase (Fragment) n=2 Tax=P...   209   4e-52
UniRef50_D1NCN8 Formate C-acetyltransferase n=1 Tax=Haemophilus ...   181   1e-43
UniRef50_B7BHI6 Putative uncharacterized protein (Fragment) n=1 ...   159   5e-37
UniRef50_Q7NEY2 Glr3745 protein n=1 Tax=Gloeobacter violaceus Re...   147   1e-33
UniRef50_B1EF41 Keto-acid formate acetyltransferase (Keto-acid f...   125   8e-27
UniRef50_B7UH18 Autonomous glycyl radical cofactor n=257 Tax=roo...   107   2e-21
UniRef50_Q70BJ5 Putative uncharacterized protein n=4 Tax=Siphovi...   107   2e-21
UniRef50_Q56EP5 Vs.6 n=5 Tax=unclassified T4-like viruses RepID=...   106   4e-21
UniRef50_Q5E2Y6 Autonomous glycyl radical cofactor n=6 Tax=Prote...   103   4e-20
UniRef50_Q6RHV7 Putative uncharacterized protein vs.6 n=1 Tax=Ae...   101   1e-19
UniRef50_C0VY69 Putative uncharacterized protein n=1 Tax=Actinom...   100   3e-19
UniRef50_O94139 Formate C-acetyltransferase (Fragment) n=2 Tax=P...    96   5e-18
UniRef50_Q76Z52 Putative uncharacterized protein vs.6 n=1 Tax=Ae...    95   7e-18
UniRef50_UPI0001742832 Formate acetyltransferase n=1 Tax=candida...    63   4e-08
UniRef50_Q4C1X2 Putative uncharacterized protein n=1 Tax=Crocosp...    59   6e-07
UniRef50_A5UFY3 Formate acetyltransferase n=1 Tax=Haemophilus in...    57   2e-06

Sequences not found previously or not previously below threshold:

UniRef50_Q39VF1 Formate C-acetyltransferase glycine radical:Pyru...   308   5e-82
UniRef50_C5V5J7 Formate C-acetyltransferase n=1 Tax=Gallionella ...   280   2e-73
UniRef50_C7ILA9 Formate C-acetyltransferase n=1 Tax=Clostridium ...   265   5e-69
UniRef50_B9M4R7 Formate C-acetyltransferase n=2 Tax=Bacteria Rep...   254   7e-66
UniRef50_Q24T37 Putative pyruvate-formate lyase n=1 Tax=Desulfit...   246   2e-63
UniRef50_D0RZP3 Formate acetyltransferase n=1 Tax=Acinetobacter ...   238   9e-61
UniRef50_Q2HBR9 Putative uncharacterized protein n=1 Tax=Chaetom...   227   1e-57
UniRef50_C3Z558 Putative uncharacterized protein n=3 Tax=Branchi...   222   3e-56
UniRef50_A3RV69 Formate acetyltransferase n=5 Tax=Ralstonia sola...   186   3e-45
UniRef50_UPI0001C3572E putative pyruvate-formate lyase n=1 Tax=C...   147   1e-33
UniRef50_UPI00019247E5 PREDICTED: hypothetical protein, partial ...   130   2e-28
UniRef50_UPI0001C420E7 pyruvate-formate lyase Pfl n=1 Tax=Methan...   121   1e-25
UniRef50_A6BGV7 Putative uncharacterized protein n=1 Tax=Dorea l...   113   3e-23
UniRef50_C0A3H9 Pyruvate-formate lyase-like protein (Fragment) n...    95   9e-18
UniRef50_C5EWH7 Putative uncharacterized protein n=2 Tax=Clostri...    67   3e-09
UniRef50_UPI00017435F3 putative formate acetyltransferase n=1 Ta...    65   1e-08
UniRef50_Q3ADQ8 Putative uncharacterized protein n=1 Tax=Carboxy...    62   8e-08
UniRef50_C8W8Y4 Putative uncharacterized protein n=3 Tax=Bacteri...    61   2e-07
UniRef50_A6BGV6 Putative uncharacterized protein n=1 Tax=Dorea l...    55   8e-06
UniRef50_C3RRJ0 Formate acetyltransferase (Fragment) n=2 Tax=Bac...    54   2e-05
UniRef50_C6Q339 Putative uncharacterized protein n=1 Tax=Clostri...    52   1e-04
UniRef50_B0PG79 Putative uncharacterized protein n=2 Tax=Clostri...    50   4e-04
UniRef50_C3RPZ3 Formate C-acetyltransferase n=1 Tax=Mollicutes b...    50   4e-04
UniRef50_UPI0001742BAE hypothetical protein cdivTM_20712 n=1 Tax...    46   0.004
UniRef50_UPI0001743618 pyruvate formate-lyase n=1 Tax=candidate ...    46   0.005
UniRef50_UPI0001742EA8 hypothetical protein cdivTM_08123 n=1 Tax...    45   0.011
UniRef50_UPI0001742D57 hypothetical protein cdivTM_16126 n=1 Tax...    44   0.023
UniRef50_D2T6G2 Autonomous glycyl radical cofactor n=1 Tax=Erwin...    44   0.023

>UniRef50_Q2G1D8 Formate acetyltransferase n=978 Tax=cellular organisms
           RepID=PFLB_STAA8
          Length = 749

 Score =  953 bits (2464), Expect = 0.0,   Method: Composition-based stats.
 Identities = 503/760 (66%), Positives = 614/760 (80%), Gaps = 11/760 (1%)

Query: 1   MSELNEKLATAWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLWDKVME 60
           M E N+  ATAW+GF  G W   V+VR+FIQ NYT YEG++SFLAG TEAT+ LW++VM+
Sbjct: 1   MLETNKNHATAWQGFKNGRWNRHVDVREFIQLNYTLYEGNDSFLAGPTEATSKLWEQVMQ 60

Query: 61  GVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIKMIE 120
             K E       D DT VASTITSHDAGY++K LE IVG+QTE P KR++ PFGGI+M +
Sbjct: 61  LSKEERERGGMWDMDTKVASTITSHDAGYLDKDLETIVGVQTEKPFKRSMQPFGGIRMAK 120

Query: 121 GSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIG 180
            +C+AY  ELD   +KIFT+YRKTHNQGVFD Y+ ++L CRK+GV+TGLPDAYGRGRIIG
Sbjct: 121 AACEAYGYELDEETEKIFTDYRKTHNQGVFDAYSREMLNCRKAGVITGLPDAYGRGRIIG 180

Query: 181 DYRRVALYGIDYLMKDKLAQFTSLQADLENGVNLEQTIRLREEIAEQHRALGQMKEMAAK 240
           DYRRVALYG+D+LM++K+  F ++  ++      E  IRLREE++EQ+RAL ++KE+  K
Sbjct: 181 DYRRVALYGVDFLMEEKMHDFNTMSTEMS-----EDVIRLREELSEQYRALKELKELGQK 235

Query: 241 YGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQ 300
           YG+D+S PA N +EA+QW Y  YLAA+K QNGAAMS GRTSTFLD+Y ERDLKAG ITE 
Sbjct: 236 YGFDLSRPAENFKEAVQWLYLAYLAAIKEQNGAAMSLGRTSTFLDIYAERDLKAGVITES 295

Query: 301 EAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNT 360
           E QE++DH +MKLR+V+F RTP+Y+ELFSGDP W TESIGG+G+DGR LVTKNSFRFL++
Sbjct: 296 EVQEIIDHFIMKLRIVKFARTPDYNELFSGDPTWVTESIGGVGIDGRPLVTKNSFRFLHS 355

Query: 361 LYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNNDDYAIACC 420
           L  +GP+PEPN+T+LWS +LP NFK + AK+SI TSS+QYENDD+MR  +  DDY IACC
Sbjct: 356 LDNLGPAPEPNLTVLWSVRLPDNFKTYCAKMSIKTSSIQYENDDIMRESY-GDDYGIACC 414

Query: 421 VSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERM 480
           VS M +GKQMQFFGARANLAKT+LYAINGG DEK   QVGP  E I  +VL YDEV ++ 
Sbjct: 415 VSAMTIGKQMQFFGARANLAKTLLYAINGGKDEKSGAQVGPNFEGINSEVLEYDEVFKKF 474

Query: 481 DHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVAADSLSAI 540
           D  MDWLA  YI +LN+IHYMHDKYSYE   MALHD +++RTMA GIAGLSVAADSLSAI
Sbjct: 475 DQMMDWLAGVYINSLNVIHYMHDKYSYERIEMALHDTEIVRTMATGIAGLSVAADSLSAI 534

Query: 541 KYAKVKPIRDEDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIP 600
           KYA+VKPIR+E+GL +DFEIEG++P++GNND RVDD+AVDLVERFM K++   TYRD+  
Sbjct: 535 KYAQVKPIRNEEGLVVDFEIEGDFPKYGNNDDRVDDIAVDLVERFMTKLRSHKTYRDSEH 594

Query: 601 TQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYA 660
           T SVLTITSNVVYGKKTGNTPDGR+AG PF PGANPMHGRDQKGA++SL+SVAK+P+   
Sbjct: 595 TMSVLTITSNVVYGKKTGNTPDGRKAGEPFAPGANPMHGRDQKGALSSLSSVAKIPYDCC 654

Query: 661 KDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAM 720
           KDGIS TFSIVP +LGK+ E +  NL  ++DGY     +++ G HLN+NV NRE L+DAM
Sbjct: 655 KDGISNTFSIVPKSLGKEPEDQNRNLTSMLDGY-----AMQCGHHLNINVFNRETLIDAM 709

Query: 721 ENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQSM 760
           E+PE+YPQLTIRVSGYAV F  LT+EQQ DVI+RTF +SM
Sbjct: 710 EHPEEYPQLTIRVSGYAVNFIKLTREQQLDVISRTFHESM 749


>UniRef50_B3DSM0 Pyruvate-formate lyase n=32 Tax=Bacteria RepID=B3DSM0_BIFLD
          Length = 791

 Score =  816 bits (2109), Expect = 0.0,   Method: Composition-based stats.
 Identities = 418/783 (53%), Positives = 539/783 (68%), Gaps = 35/783 (4%)

Query: 5   NEKLATAWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLWDKVMEGVKL 64
            E  A AW GFT+G+WQ +++VRDFIQKNYTPYEGDE+FLA ATE T  LW  + +    
Sbjct: 12  EELDAKAWAGFTEGNWQKDIDVRDFIQKNYTPYEGDETFLAPATEKTKHLWKYLDDNYLA 71

Query: 65  ENRTHAPVDFDTAVASTITSHDAGYINK-QLEKIV-GLQTEAPLKRALIPFGGIKMIEGS 122
             R     D DT   + + +  AGYI+  +++ +V GLQT+ P KRA++P GG +M+E +
Sbjct: 72  VERKQRVYDVDTHTPADVDAFPAGYIDSPEVDNVVVGLQTDVPCKRAMMPNGGWRMVEQA 131

Query: 123 CKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDY 182
            K   +E DP IKKIFT+YRKTHN GVF VYT  I   R + +LTGLPDAYGRGRIIGDY
Sbjct: 132 IKEAGKEPDPEIKKIFTKYRKTHNDGVFGVYTKQIKVARHNKILTGLPDAYGRGRIIGDY 191

Query: 183 RRVALYGIDYLM--KDKLAQFTSLQADLENGVNLEQTIRLREEIAEQHRALGQMKEMAAK 240
           RRVALYG++ L+  K +       + D      +E  IR REE  EQ +AL ++  +  +
Sbjct: 192 RRVALYGVNKLIAFKKRDKDSVPYRNDF-TEPEIEHWIRFREEHDEQIKALKKLINLGNE 250

Query: 241 YGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQ 300
           YG D+S PA  AQEA+QWTY GYLA++KSQ+GAAMSFGR S FLD YIERDL+AGKITE 
Sbjct: 251 YGLDLSRPAQTAQEAVQWTYMGYLASIKSQDGAAMSFGRNSAFLDCYIERDLQAGKITET 310

Query: 301 EAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLN- 359
           +AQE++D++VMKLR+VRFLRT +YD +FSGDP WAT S  G G DGR++VTK SFR LN 
Sbjct: 311 DAQELIDNIVMKLRIVRFLRTKDYDSIFSGDPYWATWSDAGFGDDGRSMVTKTSFRLLNT 370

Query: 360 -TLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNNDDYAIA 418
            TL  +GP PEPN+TI W  KLP  +K+F AK+SIDTS++QYE+D  +R  +  DD AIA
Sbjct: 371 LTLEHLGPGPEPNITIFWDPKLPEAYKRFCAKISIDTSAIQYESDKEIRSHW-GDDAAIA 429

Query: 419 CCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKS-----EPIKGDVLNY 473
           CCVSPM VGKQMQFF AR N AK +LYAINGG DE   MQV  K       P     L+Y
Sbjct: 430 CCVSPMRVGKQMQFFAARVNSAKALLYAINGGRDEMTGMQVIDKGVIEPITPEADGTLDY 489

Query: 474 DEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVA 533
           ++V    +  ++WL++ Y+ ALNIIHYMHDKY+YE+  MALHD++V RT+ CG++GLS+A
Sbjct: 490 EKVKNNYEKALEWLSETYVMALNIIHYMHDKYAYESIEMALHDKEVYRTLGCGMSGLSIA 549

Query: 534 ADSLSAIKYAKVKPIRDEDG-----------------LAIDFEIEGEYPQFGNNDPRVDD 576
           ADSL+A+KYAKV PI ++D                  L + +  EGE+P +GN+D R DD
Sbjct: 550 ADSLAAVKYAKVYPIYNKDAKTLEGHEYEYVEGADDDLIVGYRTEGEFPVYGNDDDRADD 609

Query: 577 LAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANP 636
           +A  +V   M ++++L  YR A+PTQS+LTITSNV YGK TG+ P G   G P+ PGANP
Sbjct: 610 IAKWVVSTVMGQVKRLPVYRGAVPTQSILTITSNVEYGKNTGSFPSGHAKGTPYAPGANP 669

Query: 637 MHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHH 696
            +G D  G + S+ SV K+ +  A DGIS T +I P+ LG+D++ R  NL G++D     
Sbjct: 670 ENGMDSHGMLPSMFSVGKIDYNDALDGISLTNTITPDGLGRDEDERIGNLVGILDA---- 725

Query: 697 EASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTF 756
             +  G  H N+NV+ +E + DA+E+PEKYP LT+RVSGYAV F  LTKEQQ DVI+RTF
Sbjct: 726 -GNGHGLYHANINVLRKETMEDAVEHPEKYPHLTVRVSGYAVNFVKLTKEQQLDVISRTF 784

Query: 757 TQS 759
            Q 
Sbjct: 785 HQG 787


>UniRef50_B4U135 Pyruvate formate-lyase n=65 Tax=Bacilli RepID=B4U135_STREM
          Length = 795

 Score =  741 bits (1913), Expect = 0.0,   Method: Composition-based stats.
 Identities = 331/768 (43%), Positives = 457/768 (59%), Gaps = 35/768 (4%)

Query: 10  TAWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLWDKVMEGVKLENRTH 69
            AWEGF   DW+ + ++  F+Q NYTPY+GDESFLAG TE +  +   + E       T 
Sbjct: 34  KAWEGFKGTDWKEKASISRFVQANYTPYDGDESFLAGVTERSLHIKKIIEETKAHYEATR 93

Query: 70  APVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIKMIEGSCKAYNRE 129
            P D      ++I    AG+I+K  E I G+Q +   K   +P GGI+M E + K    E
Sbjct: 94  FPYD---TRPTSIADIPAGFIDKDKELIFGIQNDELFKLNFMPKGGIRMAETTLKENGYE 150

Query: 130 LDPMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYG 189
            DP + +IFT++  T N G+F  YT +I R R +  +TGLPDAY RGRIIG Y R+ALYG
Sbjct: 151 PDPAVHEIFTKHVTTVNDGIFRAYTSNIRRARHAHTVTGLPDAYSRGRIIGVYARLALYG 210

Query: 190 IDYLMKDKLAQFTSLQADLENGVNLEQTIRLREEIAEQHRALGQMKEMAAKYGYDISGPA 249
            DYLM++K+  + ++          E++IRLREEI  Q++ALG++ ++   YG D+  PA
Sbjct: 211 ADYLMQEKVNDWNAITEID------EESIRLREEINLQYQALGEVVKLGDLYGVDVRRPA 264

Query: 250 TNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHL 309
            N +EAIQW    ++A  +  NGAA S GR    LD++ ERDL  G  TE E QE VD  
Sbjct: 265 ENVKEAIQWVNIAFMAVCRVINGAATSLGRVPIVLDIFAERDLARGTFTESEIQEFVDDF 324

Query: 310 VMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPE 369
           V+KLR V+F RT  YD L+SGDP + T S+ GMG DGR  VTK  +RFLNTL  +G SPE
Sbjct: 325 VLKLRTVKFARTKAYDALYSGDPTFITTSMAGMGNDGRHRVTKMDYRFLNTLDNIGNSPE 384

Query: 370 PNMTILWSEKLPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNNDDYAIACCVSPMIVGKQ 429
           PN+T+LW++KLP  F+++   +S   SS+QYE    M  D   +   I+CCVSP+    +
Sbjct: 385 PNLTVLWTDKLPYAFRRYCMHMSHKHSSIQYEGVTTMAKDGYGEMSCISCCVSPLDPENE 444

Query: 430 M-----QFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFM 484
                 Q+FGAR N+ K +L  +NGG D+  K       +P+  DVL++D V    +  +
Sbjct: 445 EQRHNIQYFGARVNVLKALLTGLNGGYDDVHKDYKVFDIDPVTDDVLDFDTVKANFEKSL 504

Query: 485 DWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVAADSLSAIKYAK 544
           DWL   Y+ ALNIIHYM DKY+YEA  MA         M  GI G +   D+LSAIKYA 
Sbjct: 505 DWLTDTYVDALNIIHYMTDKYNYEAVQMAFLPSHQRANMGFGICGFANTVDTLSAIKYAT 564

Query: 545 VKPIRDEDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSV 604
           VKPIRDEDG   D+E  G+YP++G +DPR ++LA  L+E +  +++    Y++A  T S+
Sbjct: 565 VKPIRDEDGYIYDYETIGDYPRWGEDDPRSNELAEWLIEAYTTRLRSHKLYKNAEATVSL 624

Query: 605 LTITSNVVYGKKTGNTP---------DGRRA---GAPFGPGANPMHGRDQKGAVASLTSV 652
           LTITSNV Y K+TGN+P         DG         F PGANP + + + G + +L S+
Sbjct: 625 LTITSNVAYSKQTGNSPVHRGVYLNEDGTTNLSQLEFFSPGANPSN-KAKGGWLQNLNSL 683

Query: 653 AKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMN 712
           A L F+YA DGIS T  + P ALGK  + +  NL  ++DGYF +     GGQH+N+NVM+
Sbjct: 684 ASLDFSYAADGISLTTQVSPRALGKTHDEQVENLVTILDGYFEN-----GGQHVNLNVMD 738

Query: 713 REMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQSM 760
              + D +   E    + +R+SGY V    LT EQ+ ++  R F + +
Sbjct: 739 LNDVYDKIMAGE---DVIVRISGYCVNTKYLTPEQKTELTQRVFHEVL 783


>UniRef50_C1N297 Predicted protein n=1 Tax=Micromonas pusilla CCMP1545
           RepID=C1N297_9CHLO
          Length = 776

 Score =  734 bits (1896), Expect = 0.0,   Method: Composition-based stats.
 Identities = 387/772 (50%), Positives = 504/772 (65%), Gaps = 43/772 (5%)

Query: 23  EVNVRDFIQKNYTPYEGDESFLAGA----TEATTTLWDKVMEGVKLENRTHAPVDFDTAV 78
            ++V  F+  N TP + D S L GA    TE TT LW    E +  E      +  D   
Sbjct: 8   RLDVAAFVAANVTPCDDDLSKLPGALADATEKTTKLWSLCRELLTQEFDA-GVLAIDATT 66

Query: 79  ASTITSHDAGYINKQ--LEKIV-GLQTEAPLKRALIPFGGIKMIEGSCKAYNRELDPMIK 135
            S++ SHDAGYI+    L+ +V GLQT APL R + P GG+++++ +   +  ELD  + 
Sbjct: 67  PSSVLSHDAGYIDGDGVLDDVVPGLQTSAPLVRGIKPLGGMRLVKRALAEHGVELDADVA 126

Query: 136 KIFTE-YRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLM 194
             F   +R+THN  VFD+YT ++   R+  ++TGLPDAYGRGR+IGDYRRVALYG+D + 
Sbjct: 127 AFFDRGWRRTHNDCVFDLYTQEMRLARRHHLVTGLPDAYGRGRVIGDYRRVALYGVDAIA 186

Query: 195 KDKLAQFTSLQADLEN---------GVNLEQTIRLREEIAEQHRALGQMKEMAAKYGYDI 245
           + K A    L  +  +           ++  T R R+E+A + +AL  +K MAA+YG D+
Sbjct: 187 ETKRADAARLAEEASSTAAAAAAGGDGDVSATFRRRDELALELKALEALKTMAARYGADV 246

Query: 246 SGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEM 305
           S PA+NA+EA++WTY  +LAA K  +GAA+S GR   F DVYIERDL+ G + E +AQE+
Sbjct: 247 SRPASNAREAVRWTYLAFLAACKENDGAAISLGRLDAFFDVYIERDLRGGVMDESDAQEL 306

Query: 306 VDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGR------------TLVTKN 353
           +DH V+KLR++R LR   YDE+F+GDP+WAT +I G    G              LVTK 
Sbjct: 307 IDHFVIKLRLIRQLRPKAYDEIFAGDPVWATCAIAGESSRGGGGGGAAAAAESRHLVTKT 366

Query: 354 SFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNND 413
           S+RF+ +L  +G +PEPNMT+LWS  LP  FK+  A+ SIDTSS+QY ND L+R  F +D
Sbjct: 367 SWRFMRSLANLGAAPEPNMTVLWSPTLPSGFKRQCARTSIDTSSVQYINDGLLRRAFKSD 426

Query: 414 DYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKS-------EPI 466
           D AIACCVS   +G   QFFGAR NLAK +L A+NGG++E    +V P S          
Sbjct: 427 DVAIACCVSGTRLGVDAQFFGARCNLAKLLLLALNGGLEELSGARVAPASIEASLGGGIA 486

Query: 467 KGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACG 526
               L YD+V  R+D +MDWLA  Y   + +IH+ HD+Y YEA++ +L D D    MA G
Sbjct: 487 PNVPLRYDDVRRRLDAYMDWLATLYRDVMALIHWSHDRYCYEAAIFSLIDTDRHYYMAYG 546

Query: 527 IAGLSVAADSLSAIKYAKVKPIRD-EDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERF 585
           +AGLSV  DSLSAIK+AKV P+ D E GL   FE EG +P +GN+D  VD +AVD+V  F
Sbjct: 547 VAGLSVVVDSLSAIKHAKVTPMLDAETGLIASFETEGTFPAYGNDDDAVDAIAVDVVTSF 606

Query: 586 MKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGA 645
           M K++ L  YRDA PT SVLTITSNV+YGK TG TPDGR AGAPF PGANPMHGRD  GA
Sbjct: 607 MNKLRALSQYRDAEPTLSVLTITSNVMYGKHTGATPDGRPAGAPFAPGANPMHGRDASGA 666

Query: 646 VASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQH 705
           ++SL SVAK+P+A+ KDGIS TFSI   +LGK  + R  NLA L+DGYF       G QH
Sbjct: 667 LSSLNSVAKVPYAHCKDGISNTFSIPGPSLGKTPDARVDNLAALLDGYFD-----RGAQH 721

Query: 706 LNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFT 757
           LNVNV++RE L+DAM +P KYP LT+RVSGYAV FN L++E Q++VI RTF 
Sbjct: 722 LNVNVLSRETLIDAMNDPMKYPNLTVRVSGYAVNFNRLSREHQEEVIARTFH 773


>UniRef50_O32799 Formate acetyltransferase n=32 Tax=Bacilli RepID=PFL_LACLM
          Length = 787

 Score =  730 bits (1884), Expect = 0.0,   Method: Composition-based stats.
 Identities = 329/774 (42%), Positives = 466/774 (60%), Gaps = 36/774 (4%)

Query: 11  AWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLWDKVMEGVKLENRTHA 70
           AW+GF   +W+++ +V  F+Q+NY PY+GDESFLAG TE T  +  K++E  K  +    
Sbjct: 13  AWDGFKGTNWRDKASVTRFVQENYKPYDGDESFLAGPTERTLKV-KKIIEDTK-NHYEEV 70

Query: 71  PVDFDTAVASTITSHDAGYIN---KQLEKIVGLQTEAPLKRALIPFGGIKMIEGSCKAYN 127
              FDT   ++I    AGYI+   K+LE I G+Q     +   +P GG+++ E     + 
Sbjct: 71  GFPFDTDRVTSIDKIPAGYIDANDKELELIYGMQNSELFRLNFMPRGGLRVAEKILTEHG 130

Query: 128 RELDPMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVAL 187
             +DP +  + ++   + N G+F  YT  I + R +  +TGLPDAY RGRIIG Y R+AL
Sbjct: 131 LSVDPGLHDVLSQTMTSVNDGIFRAYTSAIRKARHAHTVTGLPDAYSRGRIIGVYARLAL 190

Query: 188 YGIDYLMKDKLAQFTSLQADLENGVNLEQTIRLREEIAEQHRALGQMKEMAAKYGYDISG 247
           YG DYLMK+K  ++ ++          +  IRL+EEI  Q++AL ++    A YG D+S 
Sbjct: 191 YGADYLMKEKAKEWDAITE------INDDNIRLKEEINMQYQALQEVVNFGALYGLDVSR 244

Query: 248 PATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVD 307
           PA N +EAIQW    Y+A  +  NGAA S GR    LD++ ERDL  G  TEQE QE VD
Sbjct: 245 PAMNVKEAIQWVNIAYMAVCRVINGAATSLGRVPIVLDIFAERDLARGTFTEQEIQEFVD 304

Query: 308 HLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPS 367
             ++KLR ++F R   YDEL+SGDP + T S+ GMG DGR  VTK  +RFLNTL T+G +
Sbjct: 305 DFILKLRTMKFARAAAYDELYSGDPTFITTSMAGMGNDGRHRVTKMDYRFLNTLDTIGNA 364

Query: 368 PEPNMTILWSEKLPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNNDDYAIACCVSPMIVG 427
           PEPN+T+LW  KLP +FK+++  +S   SS+QYE  + M  D   +   I+CCVSP+   
Sbjct: 365 PEPNLTVLWDSKLPYSFKRYSMSMSHKHSSIQYEGVETMAKDGYGEMSCISCCVSPLDPE 424

Query: 428 KQ-----MQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDH 482
            +     +Q+FGAR N+ K ML  +NGG D+  K       EP++ ++L+YD VME  D 
Sbjct: 425 NEEGRHNLQYFGARVNVLKAMLTGLNGGYDDVHKDYKVFDIEPVRDEILDYDTVMENFDK 484

Query: 483 FMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVAADSLSAIKY 542
            ++WL   Y+ A+NIIHYM DKY+YEA  MA     V   M  GI G +   DSLSAIKY
Sbjct: 485 SLNWLTDTYVDAMNIIHYMTDKYNYEAVQMAFLPTKVRANMGFGICGFANTVDSLSAIKY 544

Query: 543 AKVKPIRDEDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQ 602
           AKVK +RDE+G   D+E+EG++P++G +D R DD+A  +++ + +K+     Y++A  T 
Sbjct: 545 AKVKTLRDENGYIYDYEVEGDFPRYGEDDDRADDIAKLVMKMYHEKLASHKLYKNAEATV 604

Query: 603 SVLTITSNVVYGKKTGNTP---------DGRRAG---APFGPGANPMHGRDQKGAVASLT 650
           S+LTITSNV Y K+TGN+P         DG         F PGANP + + + G + +L 
Sbjct: 605 SLLTITSNVAYSKQTGNSPVHKGVFLNEDGTVNKSKLEFFSPGANPSN-KAKGGWLQNLR 663

Query: 651 SVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEG----GQHL 706
           S+AKL F  A DGIS T  + P ALGK  + +  NL  ++DGYF   A I G    GQH+
Sbjct: 664 SLAKLEFKDANDGISLTTQVSPRALGKTRDEQVDNLVQILDGYFTPGALINGTEFAGQHV 723

Query: 707 NVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQSM 760
           N+NVM+ + + D +   E    + +R+SGY V    LT EQ+Q++  R F + +
Sbjct: 724 NLNVMDLKDVYDKIMRGE---DVIVRISGYCVNTKYLTPEQKQELTERVFHEVL 774


>UniRef50_A0Q2M5 Pyruvate formate-lyase n=9 Tax=Bacteria RepID=A0Q2M5_CLONN
          Length = 803

 Score =  648 bits (1671), Expect = 0.0,   Method: Composition-based stats.
 Identities = 178/747 (23%), Positives = 311/747 (41%), Gaps = 89/747 (11%)

Query: 90  INKQLEKIVGLQTEAPLKRALIPFGGIK-MIEGSCKAYNR---------ELDPMIKKIFT 139
           + ++ E IVG  T+      + P    K ++E   K   R         E+   +  IF 
Sbjct: 67  VIREGELIVGSLTKNSRSAQVFPEFSNKWLVEEFEKLPKRTSDSFQISEEVKSELIDIFK 126

Query: 140 EYRKTHNQGVFDVYTP-DILRCRKSGVLTGLPDAY-GRGRIIGDYRRVALYGIDYLMKD- 196
            +       +   Y P + L    + V T     + G G I  DY++V   G   ++++ 
Sbjct: 127 YWEGKTVSELATSYMPKETLEAMGAKVFTVANYYFNGLGHISVDYKKVLELGFKGIIEEI 186

Query: 197 ----------------KLAQFTSLQADLENGVNL-EQTIRLREEIAEQHRALG---QMKE 236
                           K   + ++    E  ++   +  +L +E++E         ++ +
Sbjct: 187 KAKMDSADKSDPEYIKKRTFWEAVIISCEAAIDYARRYAKLAKELSENTEDCKRKEELLK 246

Query: 237 MAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGK 296
           +A         PAT   EA Q  +F         NG A+S  R   ++  Y + D+    
Sbjct: 247 IAEICSKVPENPATTFYEACQSFWFVQAIISLESNGHAISPARFDQYMYPYFKSDVDNNV 306

Query: 297 ITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFR 356
           +T++E +E++  L +K   +  +R     + FSG  ++    +GG   +G+    + S+ 
Sbjct: 307 VTKEENREILQCLWVKFNDLTKVRDETTTKAFSGYSMFQNLIVGGQTEEGKDATNELSYM 366

Query: 357 FLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVS-IDTSSLQYENDDLMRPDF----- 410
            L+   ++   P+P++++    K P  F     +++ + T    + ND+++ P       
Sbjct: 367 CLDATGSL-KLPQPSLSVRIWSKTPEEFLIRTCELTRLGTGLPAFYNDEVIIPMLVNNGM 425

Query: 411 ---NNDDYAIACCVSPMIVGKQMQFF-GARANLAKTMLYAINGGVDEKLKMQVGPKSEPI 466
              +  DYAI  CV P   GK   ++  A  NLA+ +   I+ G       QVGPK+   
Sbjct: 426 TLEDARDYAIVGCVEPQKPGKTDGWYDAAFFNLAQILKLTIDNGK--MDGKQVGPKTGEF 483

Query: 467 KGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACG 526
           + +  + DEV+E     M++   Q ++A N +   H + +    L A+ D  + +  +  
Sbjct: 484 E-EFKDIDEVIEAYKKQMEYFVAQMVSADNCVDIAHRERAPLPFLSAMLDDCIAKGKSIQ 542

Query: 527 ------------IAGLSVAADSLSAIK---YAKVKPIRDEDGLAIDFEI----------- 560
                         G++   DS  AIK   +   K   D+   A+D              
Sbjct: 543 EGGGHYRFSGPLGVGIANVGDSFMAIKKLVFDDEKITLDKLKQALDGNFGKDEKDEGKKN 602

Query: 561 ---------EGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNV 611
                        P+FGN+   VD+   +    +  ++ K    R       +  +++NV
Sbjct: 603 ELQGIKQMLLHRAPKFGNDIDEVDEFTREGALIYCNEVLKHFNQRGGKFLPGLYPVSNNV 662

Query: 612 VYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIV 671
             G   G TPDGR A  P   G +P  G D  G  A+  SVAKL    A  G  +     
Sbjct: 663 HLGSLVGATPDGREAYQPIADGVSPTRGADVNGPTAAANSVAKLEHYAAPSGTLFNQKFN 722

Query: 672 PNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTI 731
           P++L  D+ +R  NL  L+  YF H+     G H+  NV+++ +LLDA ++PEKY  L +
Sbjct: 723 PSSLKGDNGLR--NLGTLIRSYFDHK-----GMHIQFNVVDKNVLLDAQKHPEKYRDLIV 775

Query: 732 RVSGYAVRFNSLTKEQQQDVITRTFTQ 758
           RV+GY+ +F  L KE Q D+I RT  +
Sbjct: 776 RVAGYSAQFICLNKEIQDDIIKRTEQE 802


>UniRef50_B2TMN7 Formate C-acetyltransferase n=13 Tax=Bacteria RepID=B2TMN7_CLOBB
          Length = 803

 Score =  635 bits (1638), Expect = e-180,   Method: Composition-based stats.
 Identities = 169/748 (22%), Positives = 299/748 (39%), Gaps = 93/748 (12%)

Query: 90  INKQLEKIVGLQTEAPLKRALIP-FGGIKMIEGSCKAYNRELDPM---------IKKIFT 139
           + +  E IVG  T+ P    + P F    +++   K   R  D           +K++F 
Sbjct: 67  VIRDNELIVGSLTKNPRSCQVFPEFSNQWLVDEFDKFEKRTSDLFKIPEETKSKLKEVFK 126

Query: 140 EYR-KTHNQGVFDVYTPDILRCRKSGVLTGLPDAY-GRGRIIGDYRRVALYGIDYLMKDK 197
            ++ KT ++      + +      + V T     + G G I  DY +V   G   ++K+ 
Sbjct: 127 YWQGKTVSELATSYMSNETKDAMNTKVFTVANYHFNGLGHISVDYPKVLEKGFLGIIKE- 185

Query: 198 LAQFTSLQADLENG-------------VNLEQTIRLREEIAEQHRALG----------QM 234
             +   + AD  N              ++ +  I+     +E  + L           ++
Sbjct: 186 -TENAIINADKSNPEYVKKKVFWDSIIISCKAAIKYANRYSELAKKLAGETLDINRKNEL 244

Query: 235 KEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKA 294
            ++A       + PA    EA Q  +F         NG A+S  R   ++  Y + D+  
Sbjct: 245 LKIAEICSKVPANPAETFYEACQSFWFVQAIISLESNGHAISPARFDQYMYPYYKNDIDN 304

Query: 295 GKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNS 354
              T++   E++  L +K   +  +R     + FSG  ++    +GG   DG+    + S
Sbjct: 305 KFATKEVNTEILHCLWVKFNDLTKVRDETTTKAFSGYSMFQNLIVGGQTPDGKDATNELS 364

Query: 355 FRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVS-IDTSSLQYENDDLMRPDF--- 410
           +  L    ++   P+P++ +    K P  F     +++ + T    + ND+++ P     
Sbjct: 365 YMCLEATGSL-KLPQPSLCVRIWSKTPDEFLIRTCELTRLGTGLPAFYNDEVVIPTLINQ 423

Query: 411 -----NNDDYAIACCVSPMIVGKQMQFF-GARANLAKTMLYAINGGVDEKLKMQVGPKSE 464
                +  DYAI  CV P   GK   ++  A  NLAK +  ++N G       QVGP++ 
Sbjct: 424 GLTIEDARDYAIVGCVEPQKPGKTDGWYDAAFFNLAKILELSMNNG--RLNGRQVGPETG 481

Query: 465 PIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMA 524
                  N D+ +      +++     + A N +   H + +    L ++ D  +    +
Sbjct: 482 EFTS-FKNIDDFINAYKKQIEYFVFHMVAADNCVDIAHAERAPLPFLSSMLDDCIGTGKS 540

Query: 525 CG------------IAGLSVAADSLSAIKYAKV-----------------------KPIR 549
                           G++   DS  AIK                            PI+
Sbjct: 541 IQEGGGHYRFSGPLGVGIANVGDSFMAIKKLIFDENKITLLKLKSAVDSNFGENEDDPIK 600

Query: 550 DEDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITS 609
             +   I   I    P+FGN+   VD+   D    + K++ K    R       +  +++
Sbjct: 601 KAEYEDIKQLILNRVPKFGNDIDEVDEFTRDGALIYCKEVLKYTNQRGGKFIPGLYPVSN 660

Query: 610 NVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFS 669
           NV  G   G TPDGR A  P   G +P  G D  G  A+  SV+KL    A  G  +   
Sbjct: 661 NVYLGSLVGATPDGRSAFKPLADGVSPTRGADVNGPTAAANSVSKLEHFAAPSGTLFNQK 720

Query: 670 IVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQL 729
             PN+L  D+ ++  NL  L+  YF  +     G H+  NV+++++L++A ++PE+Y  L
Sbjct: 721 FNPNSLQGDNGLK--NLGSLIRSYFDRK-----GMHIQFNVIDKKVLVEAQKHPEQYRDL 773

Query: 730 TIRVSGYAVRFNSLTKEQQQDVITRTFT 757
            +RV+GY+ +F  L K  Q D+I RT  
Sbjct: 774 IVRVAGYSAQFICLDKGVQDDIIKRTEQ 801


>UniRef50_B5I3J0 Truncated formate acetyltransferase n=8 Tax=Bacteria
           RepID=B5I3J0_9ACTO
          Length = 680

 Score =  618 bits (1593), Expect = e-175,   Method: Composition-based stats.
 Identities = 312/540 (57%), Positives = 387/540 (71%), Gaps = 13/540 (2%)

Query: 5   NEKLAT-AWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLWDKVMEGVK 63
           +++ AT AW GF    W+  V+VRDFIQ N+TPYEGD SFL G T+ T  +W+ V   + 
Sbjct: 145 DDRTATDAWRGFAGTGWRERVDVRDFIQANFTPYEGDASFLTGPTDRTRAVWETV-SALF 203

Query: 64  LENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIKMIEGSC 123
            E R+   +D DTA  STITSH  GYI++  E IVGLQT+APLKRA++P GG++M+E   
Sbjct: 204 PEERSRGVLDVDTATPSTITSHAPGYIDRDRELIVGLQTDAPLKRAIMPNGGLRMVENGL 263

Query: 124 KAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYR 183
           +AY  E DP + ++F  YRKTHN GVFD YTP++   RK+G++TGLPDAYGRGRIIGDYR
Sbjct: 264 EAYGYEPDPFVTRVFGTYRKTHNDGVFDAYTPEMRAARKAGIITGLPDAYGRGRIIGDYR 323

Query: 184 RVALYGIDYLMKDKLAQFTSLQADLENGVNLEQTIRLREEIAEQHRALGQMKEMAAKYGY 243
           RVALYG D L++ K A+    +A L+   +    IR REE+AEQ RALG++ EMAA YG 
Sbjct: 324 RVALYGTDRLIEAKRAE----RALLDVRPSTADVIRDREELAEQTRALGELSEMAATYGC 379

Query: 244 DISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQ 303
           D+S PAT A EA+QW Y GYLAAVK QNGAAMS GRTSTFLDVY+ RDL  G I E  AQ
Sbjct: 380 DVSRPATTAHEAVQWLYLGYLAAVKEQNGAAMSLGRTSTFLDVYLRRDLTDGLIDESRAQ 439

Query: 304 EMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYT 363
           E++D  V+KLR+VRFLRTPEYD LFSGDP W TESIGGMG DGRTLVT+ SFRFL TLY 
Sbjct: 440 ELIDDFVIKLRIVRFLRTPEYDALFSGDPTWVTESIGGMGADGRTLVTRTSFRFLQTLYN 499

Query: 364 MGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNNDDYAIACCVSP 423
           +GP+PEPN+T+LWS +LP  FK+F A+VSIDTS++QYE+DDL RP    DD AIACCVS 
Sbjct: 500 LGPAPEPNLTVLWSPRLPTGFKEFCAQVSIDTSAVQYESDDLTRP-RTGDDTAIACCVSA 558

Query: 424 MIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHF 483
           M VG+QMQFFGAR NLAK +LYA+NGG DE    Q+ P + P+ G+ L+YDE+    D  
Sbjct: 559 MAVGRQMQFFGARVNLAKALLYAVNGGRDEMTGDQIAPPTPPLTGEYLDYDELSAAYDRV 618

Query: 484 MDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVAADSLSAIKYA 543
           +DWLAK Y+ ALN+IH     ++ +  L A  D    RT  C  A   VA+ +  + + A
Sbjct: 619 LDWLAKTYVDALNVIHL----HARQVRLRARGDG-AARTTPC-TASWPVASPACRSPRTA 672


>UniRef50_B1C5P6 Putative uncharacterized protein n=3 Tax=Bacteria
           RepID=B1C5P6_9FIRM
          Length = 824

 Score =  604 bits (1558), Expect = e-171,   Method: Composition-based stats.
 Identities = 176/748 (23%), Positives = 305/748 (40%), Gaps = 94/748 (12%)

Query: 92  KQLEKIVGLQTEAPLKRALIPFGGIKMIEGSCKAY----------NRELDPMIKKIFTEY 141
           +  + ++G Q     +  L P      I      +          N E   ++++I   +
Sbjct: 89  EDEQLVIGNQASGIRRAPLFPEYSWDWIFKEIDEFEKRPSDVFYVNEENKKIMREILPLW 148

Query: 142 R-KTHNQGVFDVYTPDILRCRKSGVLTGLPDAY-GRGRIIGDYRRVA---LYGIDYLMKD 196
           + KT    V    T ++L  +K GVL    +   G G II ++ +V      GI    +D
Sbjct: 149 KGKTLKDRVLKTQTKEVLEDKKVGVLGWEGNVTAGEGHIIMNFEKVLKVGFRGIVNEAED 208

Query: 197 KLAQFTSLQADLENGVN---------------LEQTIRLREE---IAEQHRALGQMKEMA 238
           KL++      D    V+               +E+ I L E    I +  +   ++K++ 
Sbjct: 209 KLSKLDYTDPDDLRKVSFYKAVKIVYSASSEFVERYIDLLEGKIIIEKDEQRKKELKQIK 268

Query: 239 AKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKIT 298
                    P T  + A+Q  +F  L +    NG +MS GR   ++  + +RD+  G + 
Sbjct: 269 KNCENIEYNPPTTFKSAVQLLWFVQLISQIEANGHSMSMGRVDKYIYPFYKRDIDKGILN 328

Query: 299 EQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFL 358
             EA+E ++   +KL  V  +R   +    +G P +    IGG  +DG++ + + S+  L
Sbjct: 329 RDEAKEYIECFYLKLFTVIKIRPWSHTRFVAGYPTYQNIIIGGKNIDGKSDLNEMSYILL 388

Query: 359 NTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKV-SIDTSSLQYENDDLMRPDF------- 410
             L  +  S EPN  I   E +P +F     KV  +        NDD++           
Sbjct: 389 EALGDIKLS-EPNFYIRCHEDMPKDFVDLMIKVIKMGFGMPALVNDDVIINSLIDRGVSK 447

Query: 411 -NNDDYAIACCVSPMIVGKQMQFFGAR------ANLAKTMLYAINGGVDEKLKMQVGPKS 463
            +  DY+   C+   + GK    +G R       N+ K M  A+NGGVD K  ++   + 
Sbjct: 448 EDAYDYSTMGCLEVQVPGK----WGYRANGKTKVNVLKIMEIALNGGVDPKSGIKT-IEG 502

Query: 464 EPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTM 523
            P      ++DEV +     M +  +  +TA NI     ++   +A    L +  + R  
Sbjct: 503 IPEFTKFTDFDEVYKAYCKAMIYYMRLQVTADNINDIAMEELVPDAFCSGLVEDCIGRGK 562

Query: 524 ACG------------IAGLSVAADSLSAIKYAKVKPIRDE---------------DGLAI 556
                          + G     +SL A+K A  +                    +G  I
Sbjct: 563 TIKEGGAVYDMISGALVGGPNVGNSLYALKKAVFEDKLLTLEDVQNAVRSNYEGIEGEKI 622

Query: 557 DFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYR------DAIPTQSVLTITSN 610
              ++ +  ++GN++   DD+ V + + ++  I      R        +   S +TI+SN
Sbjct: 623 RLLLQNKIDKYGNDNDEADDMVVKIYKPYIDNIASYKNTRFGRGPIGGMFIPSTVTISSN 682

Query: 611 VVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSI 670
           V  G K G TPDGR+   P   G +PMHG ++ G  + + SV+KL       G       
Sbjct: 683 VPDGAKVGATPDGRKDEEPTAEGVSPMHGTEKNGPTSVINSVSKLETRKMTGGQLLNMRF 742

Query: 671 VPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLT 730
            P  +    +  K     L++ +F      + G H+  N+++ + L+ A + PEKY  L 
Sbjct: 743 NPTTVKTKKDEEK--FYALIEAFFK-----KNGWHVQFNMISTDTLIKAQKEPEKYQDLV 795

Query: 731 IRVSGYAVRFNSLTKEQQQDVITRTFTQ 758
           +RV+GY+  F SL K  Q D+I+R   +
Sbjct: 796 VRVAGYSALFTSLDKITQDDIISRMEYE 823


>UniRef50_P75793 Putative formate acetyltransferase 3 n=109 Tax=Bacteria
           RepID=PFLF_ECOLI
          Length = 810

 Score =  604 bits (1558), Expect = e-171,   Method: Composition-based stats.
 Identities = 171/748 (22%), Positives = 316/748 (42%), Gaps = 89/748 (11%)

Query: 92  KQLEKIVGLQTEAPLKRALIPFGGIKMIE-GSCKAYNR---------ELDPMIKKIFTEY 141
           K  E I+G Q        + P   +  IE       +R         E   ++ ++   +
Sbjct: 68  KHDELIIGNQASEVRAAPIFPEYTVSWIEKEIDDLADRPGAGFAVSEENKRVLHEVCPWW 127

Query: 142 R-KTHNQGVFDVYTPDILRCRKSGVLTGLPDAY-GRGRIIGDYRRVALYGIDYLMKDKLA 199
           R +T     + ++T +      +G++    +   G   +  ++  +   G+D L ++   
Sbjct: 128 RGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLREEVAE 187

Query: 200 Q-----------------FTSLQADLEN-GVNLEQTIRLREEIAE---QHRALGQMKEMA 238
           +                   ++   L     ++E+   L  E+A    +     ++  MA
Sbjct: 188 RRSRINLTVLEDLHGEQFLKAIDIVLVAVSEHIERFAALAREMAATETRESRRDELLAMA 247

Query: 239 AKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGK-I 297
                    P     +A+Q  YF  L      NG ++SFGR   +L  Y  RD++  + +
Sbjct: 248 ENCDLIAHQPPQTFWQALQLCYFIQLILQIESNGHSVSFGRMDQYLYPYYRRDVELNQTL 307

Query: 298 TEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMG-LDGR--TLVTKNS 354
             + A EM+    +KL  V  +R+  + +  +G P++   +IGG   +DG+    V   S
Sbjct: 308 DREHAIEMLHSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQNLVDGQPMDAVNPLS 367

Query: 355 FRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSI-DTSSLQYENDDLMRPDF--- 410
           +  L +   +  S +PN+++ +   +  +F     +V         + ND+++ P+F   
Sbjct: 368 YAILESCGRL-RSTQPNLSVRYHAGMSNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKL 426

Query: 411 -----NNDDYAIACCVSPMIVGK-QMQFFG-ARANLAKTMLYAINGGVDEKLKMQVGPKS 463
                +  DYA   C+   + GK   +  G +  N A+ ML A+ GG D        P+ 
Sbjct: 427 GIEPQDAYDYAAIGCIETAVGGKWGYRCTGMSFINFARVMLAALEGGHDATSGKVFLPQE 486

Query: 464 EPIK-GDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRT 522
           + +  G+  N+DEVM+  D  + +  ++ I    ++  M ++  ++    AL D  + R 
Sbjct: 487 KALSAGNFNNFDEVMDAWDTQIRYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERA 546

Query: 523 MAC--------GIAGLSVAADSLSAIKYAKVKPIRDE---------DGLAIDF------- 558
            +          ++GL V   +L     A  K + ++           LA DF       
Sbjct: 547 KSIKQGGAKYDWVSGLQVGIANLGNSLAAVKKLVFEQGAIGQQQLAAALADDFDGLTHEQ 606

Query: 559 ---EIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYR------DAIPTQSVLTITS 609
               +    P++GN+D  VD L     + ++ ++++ H  R               +I++
Sbjct: 607 LRQRLINGAPKYGNDDDTVDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISA 666

Query: 610 NVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFS 669
           NV +G +T  TPDGR+A  P   GA+P  G D  G  A + SV KLP A    G+     
Sbjct: 667 NVPFGAQTMATPDGRKAHTPLAEGASPASGTDHLGPTAVIGSVGKLPTAAILGGVLLNQK 726

Query: 670 IVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQL 729
           + P  L  ++E  K  L  L+  +F     +  G H+  N+++RE LLDA ++P++Y  L
Sbjct: 727 LNPATL--ENESDKQKLMILLRTFFE----VHKGWHIQYNIVSRETLLDAKKHPDQYRDL 780

Query: 730 TIRVSGYAVRFNSLTKEQQQDVITRTFT 757
            +RV+GY+  F +L+ + Q D+I RT  
Sbjct: 781 VVRVAGYSAFFTALSPDAQDDIIARTEH 808


>UniRef50_C6VIV4 Formate C-acetyltransferase n=25 Tax=Bacteria RepID=C6VIV4_LACPJ
          Length = 814

 Score =  595 bits (1535), Expect = e-168,   Method: Composition-based stats.
 Identities = 175/744 (23%), Positives = 302/744 (40%), Gaps = 85/744 (11%)

Query: 92  KQLEKIVGLQTEAPLKRALIPFGGIK-MIEGSCKAYNRELDPMI---------KKIFTEY 141
           +    IVG Q        + P   +  +I+       R  D            + I   +
Sbjct: 78  EDDTLIVGNQARQNRWAPVFPEYSMNWVIDELDTFEKRPGDVFYITEKSKEELRAIAPFW 137

Query: 142 -RKTHNQGVFDVYTPDILRCRKSGVLTGLPDAY-GRGRIIGDYRRVALYGI--------- 190
              T     +  +          G++    +   G G I  DY+ V   G+         
Sbjct: 138 KHNTLEDRGYASFPEASRIFYDLGIIGADGNITSGDGHIAVDYKNVVNKGLKWYEDRIKT 197

Query: 191 -----DYLMKDKLAQFTSLQADLENGVNLEQTIRLREEIA-EQHRAL------GQMKEMA 238
                D    ++  Q+   +A L     +    +   ++A +Q +         Q++++A
Sbjct: 198 ALANLDLTDFNQQKQYYFYKAGLIVIDAIHNFAKRYAQLASKQAQNTTSATRKAQLEKIA 257

Query: 239 AKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKIT 298
                    PA +  EAIQ  +  +L      NG ++S+GR   +LD + E DLK G I 
Sbjct: 258 QILNKVPYEPANSFYEAIQAVWLVHLTLQIESNGHSVSYGRLDQYLDPFYEHDLKTGAID 317

Query: 299 EQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFL 358
              A E++ +L +K   +  +R+ ++ E  +G P++   +IGG   DG+  V   S+  L
Sbjct: 318 ANGATELLTNLCLKTLTINKVRSWQHTEFSAGSPLYQNITIGGQTPDGKDAVNPTSYLIL 377

Query: 359 NTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKV-SIDTSSLQYENDDLMRPDF------- 410
             +      P+PN+T+ +   L   F +   +V         + ND+++ P F       
Sbjct: 378 RAI-AQAHLPQPNLTVRYHHGLSDKFMRECVEVIKQGLGMPAFNNDEIIIPSFIRRGVKK 436

Query: 411 -NNDDYAIACCVSPMIVGK-QMQFFG-ARANLAKTMLYAINGGVDEKLKMQVGPKSEPIK 467
            +  +Y+   CV   I GK   +  G +  N  + +L  +NGG+D +   ++ P      
Sbjct: 437 EDAYNYSAIGCVETAIPGKWGYRCTGMSFINFPRVLLLIMNGGIDPESGKRLLPDYGKFT 496

Query: 468 GDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGI 527
            D+ ++D++M   D  +  + +Q +   N      ++   +     L D  + R      
Sbjct: 497 -DMTSFDQLMTAWDKALREMTRQSVIIENSCDLALEQNYPDILCSVLTDDCIGRGKTIKE 555

Query: 528 ------------AGLSVAADSLSAIK---------------YAKVKPIRDEDGLAIDFEI 560
                        G++  ADSL+AIK               +A      DEDG  I   +
Sbjct: 556 GGAVYDFISGLQVGIANLADSLAAIKKLVFEEKKLTTTQLWHALTTDFADEDGEKIRQML 615

Query: 561 EGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYR------DAIPTQSVLTITSNVVYG 614
             + P++GN+D  VDDL V+  + ++ +I K    R        +      +I++NV  G
Sbjct: 616 INDAPKYGNDDDYVDDLIVEAYKPYIDEIAKYKNTRYGRGPIGGLRYAGTSSISANVGQG 675

Query: 615 KKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNA 674
             T  TPDGR A  P   G +P H  D  G  A   SV+KL       G+     + P  
Sbjct: 676 HSTLATPDGRHARTPLAEGCSPEHAMDTNGPTAVFKSVSKLSTKDITGGVLLNQKMSPQI 735

Query: 675 LGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVS 734
           L  D+   K  L  L+  +F+       G H+  N+++R+ L+DA  +P+K+  L +RV+
Sbjct: 736 LRSDESCMK--LVALLRTFFNRLH----GYHVQYNIVSRDTLIDAQNHPDKHRDLIVRVA 789

Query: 735 GYAVRFNSLTKEQQQDVITRTFTQ 758
           GY+  F  L+KE Q D+I RT   
Sbjct: 790 GYSAFFVGLSKETQDDIIERTEQS 813


>UniRef50_B2TJX0 Formate C-acetyltransferase n=9 Tax=Bacteria RepID=B2TJX0_CLOBB
          Length = 801

 Score =  595 bits (1535), Expect = e-168,   Method: Composition-based stats.
 Identities = 168/752 (22%), Positives = 298/752 (39%), Gaps = 98/752 (13%)

Query: 89  YINKQLEKIVGLQTEAPLKRALIPFGGIKMIEGSCKAYN----RELDPMI---------K 135
           YI K  E IVG Q+       + P   ++ IE   K Y     RE D             
Sbjct: 63  YI-KDGELIVGNQSFDERTAPIFPEYAVQWIEDELKEYGNFNKREGDNFYINEKNIDELL 121

Query: 136 KIFTEYR-KTHNQGVFDVYTPDILRCRKSGVLTGLPDAY-GRGRIIGDYRRVALYGIDYL 193
           +I   ++ KT     + +   +I +     V+ G  +   G G I+ D+ +    G+  +
Sbjct: 122 EIVQYWKGKTLKDKCYGIMPEEIKKAINVKVIHGEGNMTSGDGHIVPDFEKALNLGLSGI 181

Query: 194 MKDKLAQFTSLQAD----LENGVNLEQTI--------------RLREEIAEQHRALGQMK 235
           +K+       +        +    LE  I               L +++A   + + +  
Sbjct: 182 IKEAEEALEKVDISENDGFKKKSFLESVIIINKAIINFGLRYSELAKKLALAEKDINRKN 241

Query: 236 EM---AAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDL 292
           E+   +            N  EA+Q  +F +L      NG + S GR   +L  Y +  +
Sbjct: 242 ELLLISDICLRIPKEAPKNFYEAVQMIWFVHLVIQIESNGHSASLGRVDQYLYPYYKEGI 301

Query: 293 KAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTK 352
           + G +TE  A+E++  L +KL  +  +R   +    +G P +   +IGG    G      
Sbjct: 302 ENGTLTEDFAKELLQCLWIKLFSILKIRPTSHAGYGAGYPTYQNVTIGGCNELGEDCTNS 361

Query: 353 NSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAA-KVSIDTSSLQYENDDLMRPDF- 410
            S+  L ++  M    +PN++          F +  A  +           D+++     
Sbjct: 362 LSYLILQSVGEM-KLTQPNLSARLFSNSSARFIRECANVIKTGFGMPALHTDEIIVQSLL 420

Query: 411 -------NNDDYAIACCVSPMIVGKQMQFFGARA------NLAKTMLYAINGGVDEKLKM 457
                  +  +Y +  CV   + GK    +G R       N+ K +   +N G DE+   
Sbjct: 421 NKGVNYKDAYNYTMVGCVEVAVPGK----WGYRCTGMSFLNMIKAVELTLNDGYDERTGE 476

Query: 458 QVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDR 517
            +   +  +     N++E+    +  + +  K  +    I     +++  +    +L D 
Sbjct: 477 TLLTGNRDLLS-FNNFEELWAAWEKNIAYYTKLTVALDKIADTNLEEF-PDIFCSSLVDD 534

Query: 518 DVIRTMACGI------------AGLSVAADSLSAIK---YAKVKPIRDEDGLAIDFEIEG 562
            + R  +                GL+ A +SL A+K   + K    ++E   A+    EG
Sbjct: 535 CIGRGKSIKEGGSIYDIVAGLQVGLANATNSLFALKDVIFDKNILSKEEVVNALKNNFEG 594

Query: 563 -----------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYR------DAIPTQSVL 605
                        P++GN+   VD++A ++ + ++ +I K  T R        I   S  
Sbjct: 595 LEGIKVKKILFSSPKYGNDIDCVDNMARNVYQTYINEISKYKTTRYGRGPIGGIYGLSTS 654

Query: 606 TITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGIS 665
            I+SNV  G  TG TPDGR A  P   GA+P+ G D +G  + L S+ KLP      G  
Sbjct: 655 GISSNVPMGCVTGATPDGRFAWTPAAEGASPVQGSDIEGPTSVLKSITKLPTILMTGGQL 714

Query: 666 YTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEK 725
                 PN L  DD+   T    L+  +   +     G H+  NV++ + L +A ++PEK
Sbjct: 715 LNMKFSPNLLVGDDQF--TKFINLIKSFVSMK-----GWHIQFNVIDTKTLREAQKDPEK 767

Query: 726 YPQLTIRVSGYAVRFNSLTKEQQQDVITRTFT 757
           Y  + +RV+GY  +F +L +  Q+D+I+RT  
Sbjct: 768 YRDVIVRVAGYCAQFVTLDQTTQEDIISRTEE 799


>UniRef50_B2ISH7 Formate acetyltransferase, putative n=59 Tax=Bacteria
           RepID=B2ISH7_STRPS
          Length = 815

 Score =  594 bits (1532), Expect = e-168,   Method: Composition-based stats.
 Identities = 175/748 (23%), Positives = 306/748 (40%), Gaps = 91/748 (12%)

Query: 89  YINKQLEKIVGLQTEAPLKRALIPFGGIKMIEGSCKAYN-RELDPMIKKIFTEYRKTHNQ 147
           YI ++   I G Q  +     + P   ++ +      +  R+ D       TE  K   +
Sbjct: 78  YIEEE-SMIAGNQASSNKDAPIFPEYTLEFVLNELDLFEKRDGDVFY---ITEETKEQLR 133

Query: 148 GVFDVYTPDILRCRKSGVLTGLPDAY--------------GRGRIIGDYRRVALYGIDYL 193
            +   +  + LR R   +L      Y              G   +  +Y+++  +G+   
Sbjct: 134 SIAPFWENNNLRARAGALLPEEVSVYMETGFFGMEGKMNSGDAHLAVNYQKLLQFGLRGF 193

Query: 194 MKDKLAQFTSLQADLENGVN------------------LEQTIRLREEIAEQ--HRALGQ 233
            +       +L       ++                   ++ + L + +AE    +   +
Sbjct: 194 EERARKAKVALDLTDPASIDKYHFYDSIFIVIDAIKVYAKRFVALAKSLAENANPKRKKE 253

Query: 234 MKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLK 293
           + E+A         PAT   EAIQ  +F         NG ++S+GR   ++  Y++ DL+
Sbjct: 254 LLEIADICSRVPYEPATTFAEAIQSVWFIQCILQIESNGHSLSYGRFDQYMYPYMKADLE 313

Query: 294 AGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKN 353
           +GK TE    E + +L +K   +  +R+  +    +G P++   +IGG   D +  V   
Sbjct: 314 SGKETEDSIVERLTNLWIKTITINKVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPL 373

Query: 354 SFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKV-SIDTSSLQYENDDLMRPDF-- 410
           S+  L ++      P+PN+T+ +   L   F     +V  +      + ND+++ P F  
Sbjct: 374 SYLVLKSV-AQTHLPQPNLTVRYHAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIA 432

Query: 411 ------NNDDYAIACCVSPMIVGK-QMQFFG-ARANLAKTMLYAINGGVDEKLKMQVGPK 462
                 +  DY+   CV   + GK   +  G +  N  K +L  +N G+D     +  P 
Sbjct: 433 KGVLEDDAYDYSAIGCVETAVPGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPS 492

Query: 463 SEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRT 522
               K D+ N+ E+    D  + +L +  +   N I    ++   +    AL D  + R 
Sbjct: 493 FGHFK-DMKNFSELENAWDKTLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRG 551

Query: 523 MACGI------------AGLSVAADSLSAIKYAKVKPIR---------------DEDGLA 555
                             G++  +DSL+AIK    +  R                E+G  
Sbjct: 552 KHLKEGGAVYDYISGLQVGIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKV 611

Query: 556 IDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYR------DAIPTQSVLTITS 609
           I   +  + P++GN+D   D L     + ++ +I K    R        I      +I++
Sbjct: 612 IQEMLIHDAPKYGNDDDYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISA 671

Query: 610 NVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFS 669
           NV  G+ T  TPDGR AG P   G +P H  DQ G  + L SV+KLP      G+     
Sbjct: 672 NVGQGRGTLATPDGRNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQK 731

Query: 670 IVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQL 729
           + P  L K+++  K  L  L+  +F+       G H+  NV++RE L+DA ++PEK+  L
Sbjct: 732 VNPQTLAKEED--KLKLIALLRTFFNRLH----GYHIQYNVVSRETLIDAQKHPEKHRDL 785

Query: 730 TIRVSGYAVRFNSLTKEQQQDVITRTFT 757
            +RV+GY+  FN L+K  Q D+I RT  
Sbjct: 786 IVRVAGYSAFFNVLSKATQDDIIGRTEH 813


>UniRef50_A8GF53 Pyruvate formate-lyase n=31 Tax=Bacteria RepID=A8GF53_SERP5
          Length = 810

 Score =  591 bits (1524), Expect = e-167,   Method: Composition-based stats.
 Identities = 160/750 (21%), Positives = 310/750 (41%), Gaps = 90/750 (12%)

Query: 90  INKQLEKIVGLQTEAPLKRALIPFGGIKMIE-GSCKAYNR---------ELDPMIKKIFT 139
           I+   E I+G Q        + P   +  IE    +  +R         E   ++ +I  
Sbjct: 67  IDND-ELIIGNQASELRAAPIFPEYTVSWIEDEIDQLADRPGAGFSISEENKAILHRICP 125

Query: 140 EYR-KTHNQGVFDVYTPDILRCRKSGVLTGLPDAY-GRGRIIGDYRRVALYGIDYLM--- 194
            +R +T     + ++T +      +G++    +   G   +  ++  +   G+D L    
Sbjct: 126 WWRGQTVQDRCYGMFTDEQRALLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLRDKV 185

Query: 195 ------------KDKLAQFTSLQADLENGVNLEQTIRLRE------EIAEQHRALGQMKE 236
                       ++   +      DL         +R  E      +   +H    +++ 
Sbjct: 186 DERRSRIHLTDWQELQQEQFLKAIDLTLEALSAHILRFAELARSMAQAESRHWRSEELQA 245

Query: 237 MAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLK-AG 295
           +A         P     +A+Q  YF  L      NG ++SFGR   +L  +  RD++   
Sbjct: 246 IAENCELIAHRPPQTFWQALQLCYFIQLTLQIESNGHSVSFGRLDQYLYPWYRRDVELEQ 305

Query: 296 KITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMG-LDG--RTLVTK 352
            +  + A EM+    +KL  +  +R+  + +  +G P++   +IGG   +DG  R  V  
Sbjct: 306 TLPRERAIEMLHSCWLKLLEINKIRSGSHSKASAGSPLYQNVTIGGQQLVDGSPRDAVNP 365

Query: 353 NSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSI-DTSSLQYENDDLMRPDF- 410
            S+  L +   +  S +PN+++ +   +  +F     +V         + ND+++ P+F 
Sbjct: 366 LSYTILESCGRL-RSTQPNLSVRYHAGMSSDFLDACVQVIRCGFGMPAFNNDEIVIPEFI 424

Query: 411 -------NNDDYAIACCVSPMIVGK-QMQFFG-ARANLAKTMLYAINGGVDEKLKMQVGP 461
                  +  DYA   C+   + GK   +  G +  N A+ +L A+  G D        P
Sbjct: 425 KLGVEPQDAYDYAAIGCIETAVGGKWGYRCTGMSFINFARVLLAALEQGRDATSGKVFLP 484

Query: 462 KSEPI-KGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVI 520
           +   + +G+  ++D+V+   D  + +  ++ I    ++  + ++ +++    AL D  + 
Sbjct: 485 QELALSRGNFSHFDQVLGAWDSQIRYYTRKSIEIECVVDSVLEENAHDILCSALVDDCIE 544

Query: 521 RTMAC--------GIAGLSVAADSLSAIKYAKVKPIRDE---------DGLAIDF----- 558
           R  +          ++GL V   +L     A  K + ++           LA DF     
Sbjct: 545 RGKSIKQGGAKYDWVSGLQVGIANLGNSLAAVRKLVFEQGAIGQQQLAAALANDFDGLSG 604

Query: 559 -----EIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYR------DAIPTQSVLTI 607
                 +    P++GN+   VD L V   + ++ ++ + H  R               +I
Sbjct: 605 EQLRQRLLNAAPKYGNDVDEVDQLLVRAYQSYIDELAQYHNTRFGRGPIGGTYYAGTSSI 664

Query: 608 TSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYT 667
           ++NV +G  T  TPDGR+A  P   GA+P  G D  G  A   S++KLP A    G+   
Sbjct: 665 SANVPFGAATLATPDGRKAHTPLAEGASPASGTDHLGPTAVFNSLSKLPTAAILGGVLLN 724

Query: 668 FSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYP 727
             + P  L  ++ V +  L  ++  +F        G H+  N+++RE LL+A ++P++Y 
Sbjct: 725 QKLNPATL--ENPVDREKLMLMLRTFFETYL----GWHVQYNIVSRETLLEAKQHPDQYR 778

Query: 728 QLTIRVSGYAVRFNSLTKEQQQDVITRTFT 757
            L +RV+GY+  F +L+ + Q D+I RT  
Sbjct: 779 DLVVRVAGYSAFFTALSPDAQDDIIARTEH 808


>UniRef50_A6LQ73 Pyruvate formate-lyase n=6 Tax=Bacteria RepID=A6LQ73_CLOB8
          Length = 784

 Score =  588 bits (1516), Expect = e-166,   Method: Composition-based stats.
 Identities = 169/761 (22%), Positives = 302/761 (39%), Gaps = 76/761 (9%)

Query: 58  VMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIK 117
           + E  K        +    A+ ++++  + G ++   E IVG +T+      + P  G  
Sbjct: 32  ITETYKENEDKPVIIKRALALKNSLSKLEIG-VD-DEELIVGNRTKGVRYGVVFPESGSS 89

Query: 118 MI-EGSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVY----TPDILRCRKSGVLTGLPDA 172
            I +       R  D     +     +T  + +   +      D++R R    +  +   
Sbjct: 90  WIDKEFESLPTRPQDKFNVNLND--IETFRKVIKPYWDGHSLEDVIRQRYGKEIDEIAKV 147

Query: 173 -------YGRGRIIGDYRRVALYGIDYLMK---DKLAQFTSLQADLENGVNL------EQ 216
                  + +G I  + R     G + + +   +K+   T    +    V +      E 
Sbjct: 148 VKINQKDHAQGHICPNCREWLALGPEGIKQRAIEKMKNSTKESKEFYESVIIVMEGAQEF 207

Query: 217 TIRLREEIAE------QHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQ 270
            +R  + + E      +   +  M ++A         PA    EA+Q  +F ++      
Sbjct: 208 MMRYHDLMKEKAESICEEELVADMLQVAEICKNISRRPAQTFHEAVQAIWFLFVILHMES 267

Query: 271 NGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSG 330
           N ++ S GR   FL  Y +RD+  G I +++A E+++ L +K   + +LR     + F+G
Sbjct: 268 NASSFSPGRMDEFLYPYYKRDIHLGNIDDKKALEIIECLWLKFNEIVYLRNSHSAKFFAG 327

Query: 331 DPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAK 390
            PI    +IGG          + SF FL     +G  P+PN+++   +       K + K
Sbjct: 328 FPIGFNIAIGGQDEKSNDFSNELSFLFLKAQEHLG-LPQPNLSVRLHKNTSEKLLKESIK 386

Query: 391 -VSIDTSSLQYENDDLMRPDF--------NNDDYAIACCVSPMIVGKQMQFF-GARANLA 440
            V+  +   Q+ ND+ + P          +  DYAI  CV     G  + +   A  NL 
Sbjct: 387 VVAKGSGMPQFFNDESVVPSMIDLGIKEKDARDYAIVGCVELTTQGNNLGWSDAAMFNLN 446

Query: 441 KTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHY 500
           K +   +NGG        +      +      Y+++ E     +D+   + I A   +  
Sbjct: 447 KVLEITLNGGKCLISGDSLSQDLGNLTT-YEKYEDLEEAFAKQIDYFIDRMILACEQVEK 505

Query: 501 MHDKYSYEASLMALHDRDVIRTMACGIAG------------LSVAADSLSAIK---YAKV 545
            H        L ++ D  + + +     G            ++  ADSL+AIK   Y + 
Sbjct: 506 AHIDVLPSPFLSSVIDDCIEKGVDVTAGGAVYNLSGIQMIQVANLADSLAAIKLLVYDEK 565

Query: 546 KPIRDEDGLAIDFEIEG----------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTY 595
           +  ++E   A+    EG            P++GN+   VD++       F  K++    Y
Sbjct: 566 RISKEELLKALQNNFEGYEVIRAMLLNRAPKYGNDIQWVDEIGAKWARYFNGKLKSYTNY 625

Query: 596 RDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGP-GANPMHGRDQKGAVASLTSVAK 654
           R       + T++++V  G+  G + DGR A AP    G +P++GRD  G  A L SV+K
Sbjct: 626 RGGKYHTGMYTVSAHVPMGENVGASADGRYAKAPLADGGMSPVYGRDIAGPTAVLKSVSK 685

Query: 655 LPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNRE 714
           L      +G       +P       E+ +   A  +  +   E       H+  NV+ +E
Sbjct: 686 LDNVLTTNGGLLNMKFLPEFFK--HEIGRDKFARFLRTFVDLEIP-----HIQFNVLRKE 738

Query: 715 MLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRT 755
            LL A ++PE Y  LT+RV+GY   F  L  E Q ++I RT
Sbjct: 739 DLLAAQKDPENYRSLTVRVAGYTAYFTELAGELQNEIIART 779


>UniRef50_O28823 Pyruvate formate-lyase 2 (PflD) n=1 Tax=Archaeoglobus fulgidus
           RepID=O28823_ARCFU
          Length = 776

 Score =  587 bits (1512), Expect = e-166,   Method: Composition-based stats.
 Identities = 154/727 (21%), Positives = 294/727 (40%), Gaps = 78/727 (10%)

Query: 93  QLEKIVGLQTEAPLKRALIPFG-GIKMIEGSCKAYNRELDPMI-----KKIFTE------ 140
             E IVG     P    + P G G+++I       NRE + ++      K+  E      
Sbjct: 60  DSELIVGTMLPNPPGAIIFPEGVGLRIINELDSLPNRETNRLMVDEEDAKVLREEIAPYW 119

Query: 141 YRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQ 200
            RKT     F +  PDI++   +G +  L +  G   +  +Y  +   G  + +++   +
Sbjct: 120 QRKTIEAFAFPL-MPDIMQILYTGSVFVLTEIAGISHVAVNYPYLLRRGFRWFLEESERR 178

Query: 201 FTSLQAD-----------LENGVNLEQTI-------RLREEIAEQH--RALGQMKEMAAK 240
             +L+                 +  E  I       +L EE+AE        ++ ++A  
Sbjct: 179 IRALEESGVYEGEKYSFYQAAKIVSEAVINYGLRYSKLAEELAESEDGERREELLKIAEI 238

Query: 241 YGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQ 300
                +       EA+Q+ +    A  +     A+S GR   +L  + ++D+  G+I  +
Sbjct: 239 CRKVPAEKPETFWEAVQFVWLVQSALHQENYEQAISMGRIDQYLYPFFKKDIGEGRINRE 298

Query: 301 EAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNT 360
            A +++ +L +K   +        ++ FSG       +IGG  + G     + ++  L  
Sbjct: 299 LAFDILANLWIKTNEIVPAFDSLLEQYFSGQATNQAVTIGGCDIYGNDATNELTYLMLEV 358

Query: 361 LYTMGPSPEPNMTILWSEKLPLNFKKFAAK-VSIDTSSLQYENDDLMRPDFNND------ 413
              +    +PN+ +  ++  P +F K  A+ +S   ++L    DD       N       
Sbjct: 359 TDRL-RLRQPNVHVRINKGSPESFLKRLAEAISSGCNNLALFFDDAAVKALKNAEVDDRD 417

Query: 414 --DYAIACCVSPMIVGKQMQFF-GARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDV 470
             +Y    CV     G        A  N+AK + YA+N GVD +   + G K+E  K   
Sbjct: 418 ALNYTTDGCVEIAPFGNSFTSSDAALINVAKALEYALNEGVDLQFGYEFGAKTEKPKF-- 475

Query: 471 LNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTM------- 523
              ++++E++   +  + K  +   N++ Y + +      L    +    + +       
Sbjct: 476 --LEDLLEKLREQVSHIVKLVVRGSNVLSYANAEVKPTPLLSLCVEDCFEKGVDVSRGGA 533

Query: 524 -----ACGIAGLSVAADSLSAIKYAK-VKPIRDEDGLAIDFEIEG---------EYPQFG 568
                     G++   DSL AI+ A       D+   A      G         + P++G
Sbjct: 534 RYNFTGIQAVGIADVGDSLVAIEGALNAGYSMDDIVEACRKNFVGYEKLHKLLLQSPKYG 593

Query: 569 NNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGA 628
           N+D   D     ++E + +++ +   +R          +T+NV +G  T   P GR++G 
Sbjct: 594 NDDDAADKYTKMVLEWYCEEVNRHRNFRGGKFAAGCYPMTTNVGFGFFTSALPSGRKSGE 653

Query: 629 PFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAG 688
           P  PG +P  G D++G  A + S +KL +    +G S T ++  + LG+  +     +  
Sbjct: 654 PLNPGVSPSTGMDREGVTAVINSASKLSYENLPNGASLTINLSSDVLGEKGDA---VIEA 710

Query: 689 LMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQ 748
           L+           G  H+  N++  ++L  A + PEKY  L +RV+G++  F  L++  Q
Sbjct: 711 LIKSSMEL-----GVMHVQFNILKEDLLRKAQQEPEKYRWLLVRVAGWSAYFVELSRPVQ 765

Query: 749 QDVITRT 755
           ++VI R 
Sbjct: 766 EEVIRRI 772


>UniRef50_D1AFQ7 Pyruvate formate-lyase n=3 Tax=Fusobacteriaceae RepID=D1AFQ7_SEBTE
          Length = 802

 Score =  586 bits (1511), Expect = e-166,   Method: Composition-based stats.
 Identities = 161/753 (21%), Positives = 292/753 (38%), Gaps = 99/753 (13%)

Query: 89  YINKQLEKIVGLQTEAPLKRALIPFGGIKMIEGSCKAYN-------------RELDPMIK 135
           YI K  E IVG Q+       L P   ++ I                      E    + 
Sbjct: 63  YI-KDGELIVGNQSSDVRTAPLFPEYAVEWIIEELNEKGNFDHRDGDKFHLPEEHKKEVL 121

Query: 136 KIFTEYR-KTHNQGVFDVYTPDILRCRKSGVLTGLPDAY-GRGRIIGDYRRVALYGIDYL 193
           +I   ++ KT  +  +     ++ +  +   + G  +   G G I+ D+ +    G+  +
Sbjct: 122 EICEYWQGKTLREKCYAQMPEELQKASQVKAVHGEGNMTSGDGHIVPDFEKALKVGLRGI 181

Query: 194 MKDKLAQFTSLQADLENG-----------VNLEQTIRLR----------EEIAEQHRALG 232
           + + +     +   +  G           +  E  I              E     +   
Sbjct: 182 INEAVEARDKVDITVFGGYDKRDFLDSIVILNEAVIDFAHRFSSLASEFAEKETDEKRKK 241

Query: 233 QMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDL 292
           ++  +A               EA+Q  +F +L      NG + S GRT  +L  + ++D+
Sbjct: 242 ELLTIAENCKNVPENSPKTFWEAVQLIWFIHLVIQIESNGHSASLGRTDQYLYEFYKKDV 301

Query: 293 KAGK-ITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVT 351
              K +  + A+E++  L +KL  V  +R   +    +G P +   +IGG   DG     
Sbjct: 302 ITDKTMDREFAKELLQCLWVKLYTVIKVRPTSHSGYGAGYPTYQNVTIGGSNYDGSDACN 361

Query: 352 KNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSI-DTSSLQYENDDLMRPDF 410
           + ++  L ++       +PN+ + +    P  F + +A V+           D+++ P  
Sbjct: 362 ELTYLILESVAE-NKMTQPNLAVRFHSNSPEKFIRESASVAATGYGMPAMHTDEIIIPAL 420

Query: 411 --------NNDDYAIACCVSPMIVGKQMQFFGARA------NLAKTMLYAINGGVDEKLK 456
                   +  +Y +  CV   + GK    +G R       N  K +   IN G D +  
Sbjct: 421 LNKGVEFKDAYNYTMVGCVEVAVPGK----WGYRCTGMTFLNFIKIVELVINDGHDPRTG 476

Query: 457 MQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHD 516
           M +   +  +  D  ++D++ +  +  + +  +  + AL+++   H +   +    +L D
Sbjct: 477 MTLYQGNGTLL-DFESFDDLWKSWEKNIAYYTRLSV-ALDVLADTHLEELPDILCSSLID 534

Query: 517 RDVIRTMACG--------IAGLSVAADSLSAIKYAKVKPIRD-------EDGLAIDFEIE 561
             + R             IAGL V   + +   YA  K + +       E   A+    E
Sbjct: 535 SCIERGKTAKEGGAKYDIIAGLQVGLSNAANAMYALKKTVFEDKVLTKEEVFEALKNNFE 594

Query: 562 G-----------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYR------DAIPTQSV 604
           G             P++GN+   +D   V   E ++++I K    R      +     S 
Sbjct: 595 GIDGERVRNILLNVPKYGNDIDEIDRFTVKTYEPYIEEIAKYKNTRYGRGPINGGYGLST 654

Query: 605 LTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGI 664
             I+SNV  G  TG TPDGR A  P   GA+P  G D KG  A L S+ KLP      G 
Sbjct: 655 SGISSNVPMGTVTGATPDGRYAYTPAAEGASPTQGTDVKGPTAVLNSIVKLPTLLITGGQ 714

Query: 665 SYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPE 724
                  P+ +  +D+  K    G++  + + +     G H+  N+++R+ L  A E+PE
Sbjct: 715 LLNQKYSPDLIKSEDQFEK--FVGIIKTFINLK-----GWHIQFNIISRDTLQAAKEDPE 767

Query: 725 KYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFT 757
           KY  + +RV+GY  +F +L    Q+D+I RT  
Sbjct: 768 KYRDIVVRVAGYCAQFVTLDPITQEDIIARTEQ 800


>UniRef50_C7X781 Pyruvate formate-lyase n=3 Tax=Bacteroidales RepID=C7X781_9PORP
          Length = 810

 Score =  582 bits (1500), Expect = e-164,   Method: Composition-based stats.
 Identities = 171/747 (22%), Positives = 293/747 (39%), Gaps = 93/747 (12%)

Query: 89  YINKQLEKIVGLQTEAPLKRALIPFGGIKMIEGS-----------------CKAYNRELD 131
           YI +  E IVG +   P      P      +E                      Y RE+ 
Sbjct: 82  YIGED-ELIVGERGPRPKAVPTFPELTCHSVEDLHILNTRELQRYTISQEDIDTYEREVI 140

Query: 132 PMIK----------KIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYG----RGR 177
           P  K           +  E+++ +  G+F  +     R      L G    YG    + R
Sbjct: 141 PYWKGRTQRERIFSHVPKEWKEAYEVGMFTEFMEQ--RAPGHTALDGKVYQYGLLDLKKR 198

Query: 178 IIGDYRRVALYGIDYL----MKDKLAQFTSLQADLENGVNL-EQTIRLREEI---AEQHR 229
           I G+     L  +D++      DK  + T++    +  + L E+   L +E+    +  R
Sbjct: 199 IEGE-----LSALDFMNDPEATDKQEELTAMSISCDAAILLAERHADLADEMSLTEKDPR 253

Query: 230 ALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNG-AAMSFGRTSTFLDVYI 288
              +++++A    +  +       EAIQ  +F +L  +   NG  AM+ G     L  + 
Sbjct: 254 RAAELRKIAEVCRWVPAHAPRTYWEAIQMYWFVHLGTITELNGWDAMNPGHFDQHLAPFY 313

Query: 289 ERDLKAGKITEQEAQEMVDHLVMKLRM-VRFLRTPEYDELFSGDPIWATESIGGMGLDGR 347
           E+++ AG +T  EA+E++    +K+       +     +       +   +IGG+  DG 
Sbjct: 314 EKEIAAGTLTRDEAKELMSCFFIKVNNHTAPPKVGITAKESGTYNDFTNLNIGGIRADGS 373

Query: 348 TLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSI-DTSSLQYENDDLM 406
             V++ S+  L T+  +    +P   I  S + P  F +   KV           N D+ 
Sbjct: 374 DGVSEVSYIMLETIEELHIL-QPGSAIHVSARTPERFLRAGCKVIRQGHGYPSVFNPDVY 432

Query: 407 RPDF--------NNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQ 458
             +         +  +   + C+     GK+        N+ K +   ++ GVD     +
Sbjct: 433 VQELMRQGKSLRDAREGGCSGCIEVGAFGKEAYVLTGYLNVPKILEVTLHNGVDPVSGRK 492

Query: 459 VGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRD 518
           VG ++   +G    Y+E+       + +     +   N I  M  KY+    L    D  
Sbjct: 493 VGLETGDPRG-FRTYEELYAAFMRQIHYFVDMKVRVSNYIDRMFAKYAPATFLSLFIDDC 551

Query: 519 VIRTM------------ACGIAGLSVAADSLSAIKYAKV--KPIRDE---DGLAIDFE-- 559
           + +                   GL    DSLS+++      K    E   D +A +FE  
Sbjct: 552 IAKGKDYYNCGPRYNTTYIQCTGLGTITDSLSSLRKHVFEDKTFTMEALLDAMADNFEGH 611

Query: 560 ------IEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVY 613
                 I    P FGN+DP  D +AV + +     I+     +      ++L+ T +V +
Sbjct: 612 EPMRQMILNRTPFFGNDDPYADQIAVRVFDDLYDAIEGKPNTKGECFHLNMLSTTCHVYF 671

Query: 614 GKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPN 673
           GK  G TP+GR AG     G +P HG D  G  A + S+ KL       G       +P+
Sbjct: 672 GKVMGATPNGRLAGRAISDGTSPSHGADIHGPSAVIKSLGKLDQVK-SGGTLLNQRFLPS 730

Query: 674 ALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRV 733
            L +++++ K  LA L+  YF       GG H+  N+++ E L  A + PE Y  L +RV
Sbjct: 731 LLWREEDISK--LASLIRSYFAL-----GGHHIQFNIVDTETLYAAQKCPEDYRDLLVRV 783

Query: 734 SGYAVRFNSLTKEQQQDVITRTFTQSM 760
           +GY+  FN +  + Q DVI RT  ++ 
Sbjct: 784 AGYSDYFNDMNADLQADVIARTEQETF 810


>UniRef50_Q18AX8 Glycerol dehydratase n=8 Tax=Clostridium RepID=Q18AX8_CLOD6
          Length = 790

 Score =  578 bits (1490), Expect = e-163,   Method: Composition-based stats.
 Identities = 160/740 (21%), Positives = 303/740 (40%), Gaps = 83/740 (11%)

Query: 93  QLEKIVGLQTEAPLKR--ALIPFGGIKMI-EGSCKAYNRELDPMI----------KKIFT 139
           + E IVG  T    +R   L P    + + +       R  DP +          K+IF 
Sbjct: 62  ENELIVG--TAGKFRRTGILTPEFSWQWVDKEMDTFDKRTQDPYVISKEQIEFIRKEIFP 119

Query: 140 EYRKTHNQGVFDVYTPD--ILRCRKSGVLTGLPDAY-GRGRIIGDYRRVAL-YGIDYLMK 195
            ++    + VF    P+        +G++          G +  DY+ +    G   + +
Sbjct: 120 YWKGKSLEEVFLARIPEDTAKILVDTGIIDNDSKWRQAVGEVTPDYQDILFVKGYKGIKE 179

Query: 196 DKLAQFTSLQADLENGVN------------------LEQTIRLREEIAEQH---RALGQM 234
           D   +   L   +   +                    ++   L +E+++Q    +   ++
Sbjct: 180 DADKKIKELDISVSENIEKIDFYKSVSIVAQGIMTLAQRYSNLAKEMSKQETDEKRKLEL 239

Query: 235 KEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKA 294
            +++       + P TN  EAIQ+ +F  L  + S+N  A++ GR   ++  Y E D + 
Sbjct: 240 IKISEICMNVPANPPTNFYEAIQFVWFVQLGGILSENPLALNLGRFDQYMYPYYENDARE 299

Query: 295 GKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNS 354
           GKITE EAQE+++ L +KL    +  +      F+G   +   ++GG   +G       S
Sbjct: 300 GKITESEAQELIEALWIKLSEWVWTISANTANYFAGYNQFQNLTVGGKKRNGTDGTNDIS 359

Query: 355 FRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAK-VSIDTSSLQYENDDLMRPDF--- 410
           +  L    ++  + +P +++  S+  P NF    AK V   T      +D          
Sbjct: 360 YMCLKATESV-KTHQPGLSVRVSQGAPDNFVMAVAKLVKQGTGFPAIHSDSAGAQMLLQD 418

Query: 411 -----NNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEP 465
                +  D++   CV P              N A  + YA+N G       ++G  ++ 
Sbjct: 419 GYDAEDARDWSNCGCVVPHFRKTGQWTSAVNINFAAALEYAMNEGKSRLTGEKMGLDTKN 478

Query: 466 IKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRT--M 523
           I  +  +++E+ +     + +L K  +    +   +H +      L    D  + +   +
Sbjct: 479 IT-EFTSFEELKDEFLKQLAYLVKSSVIGTTVAQQIHKEMVPRPFLSTCVDGCLDKGVDL 537

Query: 524 ACGIA-----------GLSVAADSLSAIKYAKVKP---IRDEDGLAIDFEIEG------- 562
           + G A           GL V ++SL+AIK    +      +E   A++ + EG       
Sbjct: 538 SKGGAKYNIGPVLTGIGLGVVSNSLAAIKKLVFEDKVTTLEELTKALNNDWEGYEELRKL 597

Query: 563 --EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNT 620
             + P++GN++  VD LA+++ + +  + +K      +    + + I++ V  GK  G T
Sbjct: 598 ALDVPKYGNDNDYVDSLAIEVSDFYYTETRKYKDIFGSKFNSAFMGISNYVPTGKIVGAT 657

Query: 621 PDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDE 680
           P GR+A  P   G +P  G D    +A++ S +K+       G      +  + +  +  
Sbjct: 658 PCGRKATKPLTEGVSPFVGTDTTSPLAAMKSASKINHDVHTGGTLLNLRLNQDLVETERG 717

Query: 681 VRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRF 740
           +R  NL  ++  YF       GG H+  N ++ + LL A ENPE+Y  L +RV+GY+ +F
Sbjct: 718 LR--NLTSMIKSYFAL-----GGFHVQFNTISNDTLLKAQENPEEYKDLLVRVAGYSTQF 770

Query: 741 NSLTKEQQQDVITRTFTQSM 760
            +L++E Q  +I R    + 
Sbjct: 771 VNLSREMQDAIIARNSHSNF 790


>UniRef50_C6A251 Pyruvate-formate lyase n=50 Tax=cellular organisms
           RepID=C6A251_THESM
          Length = 823

 Score =  576 bits (1485), Expect = e-163,   Method: Composition-based stats.
 Identities = 158/702 (22%), Positives = 290/702 (41%), Gaps = 76/702 (10%)

Query: 117 KMIEGSCKAYNRELDPMIK----------KIFTEYRKTHNQGVFDVYTPDILRCRKSGVL 166
           K+ E + + Y  E+ P  K           +  E+   +  G++  +       R  G  
Sbjct: 136 KVDEETRELYKNEIIPFWKGRAMRDMIFETLPQEWIDAYEAGIWTEFMEQ----RSPGHT 191

Query: 167 TGLPDAYGRGRIIGDYRRVALYGIDYL------MKDKLAQFTSLQADLEN-GVNLEQTIR 219
            G    +  G  + D +      +  L        +K+ +  ++    E   +  ++   
Sbjct: 192 AGGGRIFRMG--VLDIKEEIKKKMGELDPSNPEYYEKMEELKAMDIVAEAILIYAKRYAE 249

Query: 220 LREEIAEQHRALG---QMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNG-AAM 275
             E++AE+ +      ++K+MA       +       EA+Q  +F ++      N   + 
Sbjct: 250 KLEKMAEEEKDPKRKKELKQMAEICKRVPAHAPRTFWEALQHYWFVHVGVTYETNPWDSF 309

Query: 276 SFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFL-RTPEYDELFSGDPIW 334
           + GR    L  + +RDL+ G++T ++A+E++    +K      + +     E       +
Sbjct: 310 NPGRIDQHLYPFYKRDLEEGRLTREKAKELLQCFWLKFNNQPAVPKVGVTAEESFTYNDF 369

Query: 335 ATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKV-SI 393
           +  ++GG+  DG   V + S+  L  L  M  + +PN  +L S K P  F   A KV   
Sbjct: 370 SKLNLGGLKKDGSDGVNELSYLILEVLSEM-RTLQPNTAVLISNKNPDRFLIEALKVVGP 428

Query: 394 DTSSLQYENDDLMRPDF--------NNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLY 445
                 + N D +            +     ++ CV     GK+        NL K +  
Sbjct: 429 GFGEPPFFNFDGVIVKMLRQGKTLEDARTSGVSGCVETGAFGKEAYILTGYFNLPKILGI 488

Query: 446 AINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKY 505
            +N G+D +   ++G ++   + +  +++E+       ++      +   +II  ++ KY
Sbjct: 489 TLNNGIDPRTGKKIGIETGDPR-NFKSFEELWNAFVKQVNHFLDIKMKGNDIIETLYAKY 547

Query: 506 SYEASLMALHDRDV------------IRTMACGIAGLSVAADSLSAIKY---AKVKPIRD 550
                +    +  V              T    + GL   ADSL+AIKY    K   + +
Sbjct: 548 LPVPFMSLWIEDCVKNAKDYNGGGTRYNTQYIQVVGLGTIADSLAAIKYHVFDKKTFVME 607

Query: 551 EDGLAIDFEIEG------------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTY--R 596
           E   A+    +G            + P+FGN+D  VD++A  +V+  +  I+       R
Sbjct: 608 ELLNALKNNWKGYEMMREILRNPEKTPKFGNDDEYVDEIAKKVVDTVVDLIEAYPPSPVR 667

Query: 597 DAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLP 656
            A      L  T +V +GK TG TPDGR AG P   G +P+ G D+KG  A   SVAK  
Sbjct: 668 KASKRAYFLPTTVHVYFGKVTGATPDGRDAGFPVSEGISPVQGMDRKGIAAVFRSVAKCD 727

Query: 657 FAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREML 716
           +     G      + P+    ++ ++K  LA L+  +F       GG H+  NV++ E+L
Sbjct: 728 WDK-TGGALLNQKLTPDLFDNEENIKK--LAQLIRTFFRL-----GGHHVQFNVISAELL 779

Query: 717 LDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQ 758
            +A + P+++  L +RV+GY+  F +L K  Q ++I RT  +
Sbjct: 780 REAQKRPQEFQDLMVRVAGYSDYFVNLPKGLQDEIIARTEHK 821


>UniRef50_B6FJR9 Putative uncharacterized protein n=1 Tax=Clostridium nexile DSM
           1787 RepID=B6FJR9_9CLOT
          Length = 794

 Score =  576 bits (1485), Expect = e-162,   Method: Composition-based stats.
 Identities = 166/739 (22%), Positives = 301/739 (40%), Gaps = 83/739 (11%)

Query: 93  QLEKIVGLQTEAPLKRALIPFGGIKMI-EGSCKAYNRELDPMI-----KKIFTEYRKTHN 146
             E IVG          L       ++ +       R+ DP I     +++F +  K   
Sbjct: 64  DQELIVGCAGSKMRGGILSADTCWSILDKELDTINERKYDPFILKPEDRQMFLDVVKPFW 123

Query: 147 QG--VFDVYTPDI----LRCRKSG-VLTGLPDAYGRGRIIGDYRRVALYGIDYLMK---- 195
           +G   ++ +   I       R SG +        G G     Y+++   GI+ +M     
Sbjct: 124 EGRSTYEAWLKQIPDDVRALRDSGQIYIDKKAVRGWGETTAGYKQIIDEGIESIMNTIKA 183

Query: 196 -------------DKLAQFTSLQADLENG-VNLEQTIRLREEIAE---QHRALGQMKEMA 238
                        DK     +L    E   +  E+  +  E +AE         ++  +A
Sbjct: 184 EREALDLTDPGAFDKDNYLQALLISAEGICIMAERYAKEAERLAELEKDEERKAELLTIA 243

Query: 239 AKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKIT 298
               +    PA   QEAIQ  YF +++    QN AA + GR   +   Y + D+++G+IT
Sbjct: 244 ETCHHVPRYPARTFQEAIQSFYFYHISIFMEQNAAAYNPGRMDQYFYPYYKVDIESGRIT 303

Query: 299 EQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFL 358
           E E QE+++ L +K       +        +G P++ T   GG+  +GR  V   S+  L
Sbjct: 304 EDEGQELLECLWVKFSEPCVFQDATTARYSAGYPMFQTLCCGGIDAEGRDAVNDISYMML 363

Query: 359 NTLYTMGPSPEPNMTILWS-EKLPLNFKKFAAKV-SIDTSSLQYENDDL--------MRP 408
                +    +PNM + +S  K P  F K  A+V S+ T    + NDD+          P
Sbjct: 364 QATQDV-LLYQPNMCVRYSMAKNPTKFLKKVAEVISLGTGFPAFYNDDVGIRMLMNKGIP 422

Query: 409 DFNNDDYAIACCVSPMIVGKQMQFFG-ARANLAKTMLYAINGGVDEKLKMQVGPKSEPIK 467
                D+  A CV   + G+   +   A  NL   + +A+  GV+ K   +V  ++    
Sbjct: 423 LKEAYDWNPAGCVETNLDGRLRHYSAFADINLGGIIEFALTNGVNRKTGRKVATETGDPT 482

Query: 468 GDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRT----- 522
                Y++    +   + +  +  +   +II  +       A  ++L  R+ ++      
Sbjct: 483 T-FETYEDFENAVKEQLKYSVRICVKGSHIIDDICMDRIVPA--LSLSFRECVKNAKDYA 539

Query: 523 ------------MACGIAGLSVAADSLSAIKYAKVKPIRDEDGLAIDFEIEG-------- 562
                       +  G+A L  + +++  + Y +     ++   A+D + EG        
Sbjct: 540 WGGAKYNTGNGIILIGVADLINSMEAIRDLVYDRKLVSMEDMVKALDADFEGYEEIQKLC 599

Query: 563 -EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTP 621
            E  ++GN+D  V+D+   ++     +I+K H+    + T  +L ++ N  +G+  G  P
Sbjct: 600 KESHKYGNDDDDVNDITSHMLTFIADEIEKYHSKFGQM-TPGILPVSGNTPFGQDVGALP 658

Query: 622 DGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEV 681
            GR+A  P   G +P  G D +G  A + SVA +P +    G      + P+ +  ++ +
Sbjct: 659 SGRKAWMPLADGISPNGGTDVEGPAAVIKSVASIPHSRYTQGTLLNMKLEPDMVKTENGI 718

Query: 682 RKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFN 741
           R+  L  L+      +       H+  NV+++E LL A + PE Y  L +RV+GY   F 
Sbjct: 719 RQ--LMALLRSLCTLDV-----YHVQFNVIDKETLLAAQKKPENYKGLLVRVAGYTAYFT 771

Query: 742 SLTKEQQQDVITRTFTQSM 760
            L +E Q ++I RT   + 
Sbjct: 772 ELGREVQDEIIARTAQSNF 790


>UniRef50_A5N4Z6 Predicted glycyl radical enzyme n=2 Tax=Clostridium kluyveri
           RepID=A5N4Z6_CLOK5
          Length = 800

 Score =  576 bits (1484), Expect = e-162,   Method: Composition-based stats.
 Identities = 155/675 (22%), Positives = 278/675 (41%), Gaps = 64/675 (9%)

Query: 132 PMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGID 191
            M K +  E+ K  + G++     + L  R  G        Y +G I  D+     Y ID
Sbjct: 140 RMNKLLPDEWHKLFDAGLY----TEFLMQRGPGHTVADGKIYRKGYI--DFINDIQYEID 193

Query: 192 YLMKDKLAQFTSLQADLENGVNL-EQTIRLREEIAEQHRAL----------GQMKEMAAK 240
           +L  +      + + +LE    + E  I   E  A+Q RAL           ++ E+A  
Sbjct: 194 HLDYNNDVLALNKKEELEGMKLVCEGMIIFGERYADQARALASVENDPQWKEELLELAEV 253

Query: 241 YGYDISGPATNAQEAIQWTYFGYLAAVKSQNG-AAMSFGRTSTFLDVYIERDLKAGKITE 299
                       ++A+Q  +F ++      N   A S G+    L+ + E+D++ G++T 
Sbjct: 254 CDVVPKHAPRTFRQAVQMYWFTHIGVTTEMNNWDAYSPGKLDQHLEPFYEKDIEEGRLTR 313

Query: 300 QEAQEMVDHLVMKLRM-VRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFL 358
           +EA E++++L ++        +     +  +    +   + G +  DG T V++ S+  L
Sbjct: 314 EEALEILENLWIQFNNQPTPPKVGITLKESATYTDFCNINTGALRPDGTTGVSEVSYLIL 373

Query: 359 NTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSIDT-SSLQYENDDLMRPDF------- 410
             +  M    +P+  +  S K P  F + A K+S        + N + +  +        
Sbjct: 374 EVMDEM-KLLQPSSNVQISRKTPEKFLREALKISRKGWGQPAFYNSEAIIQELLFLGKSI 432

Query: 411 -NNDDYAIA-CCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKG 468
            +  +  IA  CV     GK+        N+ K     +N G D   K QVG      + 
Sbjct: 433 DDARESGIASGCVETGTAGKEAYVLTGYLNIPKIFELVLNRGFDSYTKKQVGLDLGDPR- 491

Query: 469 DVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDV--------- 519
              +Y EV +     ++++    I   N+I  M+ +Y     L  + D  +         
Sbjct: 492 KFKSYQEVYDAFYKQLEYVVNVKIAGNNLIERMYMEYMPVPLLSVITDDCIKSGVDYNAG 551

Query: 520 ---IRTMACGIAGLSVAADSLSAIK---YAKVKPIRDEDGLAIDFEIEG----------E 563
                T      G++   DSL +IK   +   K   DE   A   + +G           
Sbjct: 552 GARYNTSYIQCVGIATITDSLVSIKKNVFEDKKFSMDELLKACKADFKGYDEIFETVYNH 611

Query: 564 YPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDG 623
            P++GN+D   DD+  D+ +     I    T + +      L  T +V +G+    +P+G
Sbjct: 612 TPKYGNDDDYADDILRDVSQSLQDAIAGRTTPKGSTTVVEFLPTTCHVYFGQVMEASPNG 671

Query: 624 RRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRK 683
           R AG P   G +P  G D+ G  + + S +K+       G        P+ +  ++ +  
Sbjct: 672 RHAGIPLPGGISPEKGADRNGPTSVVKSASKIDQLK-TGGALLNQKFTPSVVQGEEGI-- 728

Query: 684 TNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSL 743
           +N+A L+  YF  +     G H+  NV++R+ LLDA ++PE+Y  L +RV+GY+  FN+L
Sbjct: 729 SNMATLVRSYFSMD-----GHHIQFNVIDRKTLLDAQKHPEEYENLIVRVAGYSDYFNNL 783

Query: 744 TKEQQQDVITRTFTQ 758
            +  Q ++I RT   
Sbjct: 784 DRALQDEIINRTEQS 798


>UniRef50_B6FX97 Putative uncharacterized protein n=4 Tax=Firmicutes
           RepID=B6FX97_9CLOT
          Length = 796

 Score =  571 bits (1471), Expect = e-161,   Method: Composition-based stats.
 Identities = 158/731 (21%), Positives = 295/731 (40%), Gaps = 78/731 (10%)

Query: 95  EKIVGLQTEAPLKRALIPFGGIKMI-EGSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVY 153
           E IVG +T+      + P  G   + +       R  D  + K   E  K   + ++  +
Sbjct: 75  ELIVGNRTKGVRYGVVFPESGCSWVNKEFETLPTRPQDKFLVK--EEDIKEFRESIYPYW 132

Query: 154 ----TPDILRCRKSGVLTGLPDA-------YGRGRIIGD---YRRVALYGIDYLMKDKLA 199
                 D+++      +  +          + +G I  D   + ++   G+    ++K+A
Sbjct: 133 NGKSMEDVIKNNYGKEINAMAKVVKINQKDHAQGHICPDSELWLKLGPQGLIDKAREKMA 192

Query: 200 QFTSLQADLEN----------------GVNLEQTIRLREEIAEQHRALGQMKEMAAKYGY 243
                Q +                      +   I    +   +      ++ +A     
Sbjct: 193 NCEENQKEFYECTILVLEGAKNFMMRYHDYILNMINNCGDDKIEDEYKESLRNVAEICKN 252

Query: 244 DISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQ 303
               P     EA+Q  +F +       N ++ S GR   +L  Y + D++ G I+EQ+A 
Sbjct: 253 LSERPPKTFHEAVQSLWFLFTILHMESNASSFSPGRMDQYLYPYYKEDIEKGIISEQDAL 312

Query: 304 EMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYT 363
           E+++ L +K   + +LR     + F+G PI    +IGG+  +G  +    S   L   Y 
Sbjct: 313 EIIECLWLKFNQIVYLRNQHSAKYFAGFPIGFNIAIGGVDENGDDIYNNLSLLILRAQYH 372

Query: 364 MGPSPEPNMTILWSEKLPLNFKKFAAK-VSIDTSSLQYENDDLMRPDF--------NNDD 414
           +G  P+PN+++  ++       + + K V+  +   Q+ ND+ +            +  +
Sbjct: 373 LG-LPQPNLSVRLNKNTSHELMQESIKVVAKGSGMPQFFNDESIIKAMIDLGIEEKDARN 431

Query: 415 YAIACCVSPMIVGKQMQFF-GARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNY 473
           YA+  CV     G  + +   A  NL K +   +N G       Q+G     ++ D   +
Sbjct: 432 YAVVGCVELTTHGNNLGWSDAAMFNLNKALELTLNEGKCLLTGEQIGLNLGKLE-DYKTF 490

Query: 474 DEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMAC-------- 525
           +++ E     +D+   + + A  ++   H      A L  + D  + + +          
Sbjct: 491 EDLEESFRKQIDYFINEMMKAEVVVEKAHQDCLPSAFLSTVIDDCLEKGLDVTRGGAKYN 550

Query: 526 --GIAGLSVA--ADSLSAIK---YAKVKPIRDEDGLAIDFEIEGE----------YPQFG 568
             GI  + VA  ADSL+AIK   Y +    ++E   A+  + +G            P++G
Sbjct: 551 LSGIQMIQVANLADSLAAIKELVYDEEMISKEELLQALRDDFKGHEITQTMLLNKAPKYG 610

Query: 569 NNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGA 628
           N+   VDDL       F ++++    YR       + T++++V  G+  G +PDGR A  
Sbjct: 611 NDVKWVDDLGTKWAGYFRERMKDYTNYRGGAYHTGMYTVSAHVPMGENVGASPDGRNALT 670

Query: 629 PFGP-GANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLA 687
           P    G +P++GRD  G  A + SV+++   Y  +G       +P     +  + K    
Sbjct: 671 PLADGGMSPVYGRDIAGPTAVIKSVSRISNDYTTNGGLLNMKFLPEFFKTETGMLK--FE 728

Query: 688 GLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQ 747
             +  +   E       H+  NV+ RE LLDA  +PE++  LTIRV+GY   F  L  + 
Sbjct: 729 SFLRAFVDLEVP-----HIQFNVVRREDLLDAKVHPERHKSLTIRVAGYTAYFVELAGKL 783

Query: 748 QQDVITRTFTQ 758
           Q ++I RT  +
Sbjct: 784 QDEIIERTAYE 794


>UniRef50_B8G188 Pyruvate formate-lyase n=1 Tax=Desulfitobacterium hafniense DCB-2
           RepID=B8G188_DESHD
          Length = 796

 Score =  569 bits (1467), Expect = e-160,   Method: Composition-based stats.
 Identities = 158/736 (21%), Positives = 288/736 (39%), Gaps = 85/736 (11%)

Query: 93  QLEKIVGLQTEAPLKRALIPFGGIK-MIEGSCKAYNRELDPMI---------KKIFTEYR 142
             E IVG     P    + P   +K +++   +   R+ D            ++I+ +++
Sbjct: 76  DKELIVGSYAGKPRGCQVFPEYDMKFLVDEMDEFALRQADKFTISEDNKAIARQIYEKWK 135

Query: 143 -KTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLM------- 194
             T      +++  +  +  +  +        G G ++ +Y +V   G+   M       
Sbjct: 136 GNTITDQALNLFPEEAAKASQQLIFLLTCLGSGIGHMLVNYEKVIQKGLAGFMLEIEELE 195

Query: 195 ----------KDKLAQFTSLQADLENGVNLEQTIRL-----REEIAEQHRALGQMKEMAA 239
                      DK   + SL    +          L      E+ A+  R   ++ ++A 
Sbjct: 196 NGLDICDPEYNDKKTYYQSLTIVCQAVCKFAGRFSLLALAQAEKTADPQRK-EELLQIAE 254

Query: 240 KYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITE 299
                 + PA N  +A+Q  +F  L      NG ++S GR   ++  Y      A +  +
Sbjct: 255 NCRRVPAQPAQNFWQALQALWFVQLVLHLESNGHSVSPGRFDQYMYPYY-----AAETDK 309

Query: 300 QEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLN 359
              +E++  L +K   +  +R      +F G P++    +GG   +G + V + S   L 
Sbjct: 310 DACEELLHCLWLKFFELNKIRNKVSSVVFGGYPMFQNIVVGGQNANGESAVNELSHLCLE 369

Query: 360 TLYTMGPSPEPNMTILWSEKLPLNFKKFAAKV-SIDTSSLQYENDDLMRPDF-------- 410
               +   P+P++++ W    P  F + A +V S  T      ND+++ P+         
Sbjct: 370 ATAKV-HLPQPSLSVRWFYGCPEEFIRHALEVVSYGTGMPALFNDEVIIPNMLQLGYTIE 428

Query: 411 NNDDYAIACCVSPMIVGKQMQF-FGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGD 469
              DYAI  C    +  K   F  G   N+ K +   I  G D   + Q   +S  ++  
Sbjct: 429 EARDYAIIGCTEMNVPHKTEPFLTGGFLNILKILELTIFDGFDPVSQTQQAFQSGCVES- 487

Query: 470 VLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTM------ 523
              ++E  +     + +  +Q++T  NI+  +H K         L    +          
Sbjct: 488 FTTFEEFQKAYYEQLSYYLRQHVTCDNILDALHGKICPTPFESMLLSDCLENGKSNLEGG 547

Query: 524 ------ACGIAGLSVAADSLSAIKYAKVKPIRD-------------EDGLAIDFEIEGEY 564
                    + G++  ADSL+ IK                      ED   +   I    
Sbjct: 548 ARYNTTTLQLVGMANVADSLATIKKLIYVEKSLTWNQLKAALQNNYEDDELLRQRIINHV 607

Query: 565 PQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGR 624
           P++GN+   VD L  D+V    ++  K  + R+     +V T+ +NV++  K G TPDGR
Sbjct: 608 PKYGNDHDFVDRLGRDVVYHCCREAAKYRSPRNGTYNIAVYTLATNVLWASKVGATPDGR 667

Query: 625 RAGAPFGP-GANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRK 683
           + G+     G +  HG D+ G  A   SV K+              + P++  + D  + 
Sbjct: 668 KMGSVLADGGVSCSHGMDKNGLTALFNSVRKIDPYKPLGSALLNIRLSPSSFNETDFQKT 727

Query: 684 TNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSL 743
                ++  +F ++     GQH+  NV +   L DA +NPEKYP L +RV+G++V F ++
Sbjct: 728 ---VDVVKSFFMNK-----GQHVQFNVFDVNALRDAQKNPEKYPLLMVRVAGFSVLFTTI 779

Query: 744 TKEQQQDVITRTFTQS 759
               Q+D+I RT   S
Sbjct: 780 ETILQEDIINRTLHSS 795


>UniRef50_A6TPN1 Formate C-acetyltransferase n=3 Tax=Clostridiaceae
           RepID=A6TPN1_ALKMQ
          Length = 789

 Score =  566 bits (1460), Expect = e-160,   Method: Composition-based stats.
 Identities = 157/734 (21%), Positives = 277/734 (37%), Gaps = 79/734 (10%)

Query: 95  EKIVGLQTEAPLKRALIPFGGIKMIE-GSCKAYNRELDPMI----------KKIFTEYRK 143
           E IVG   E      L P      ++        R  DP +          KKIF  ++ 
Sbjct: 63  ELIVGSIGEFRKCGILTPEFSWTWVDREMDNFDERVQDPYVMTDEQRTFVRKKIFPYWKG 122

Query: 144 THNQGVFDVYTPD--ILRCRKSGVLTGLPDAY-GRGRIIGDYRRVALY-GIDYLMKDKLA 199
              +  F    P+        +G++          G +  DY+ V    G   ++K+   
Sbjct: 123 KSLEEAFLAQLPEKTAKVAVDTGIVDNDSKWRQAVGEMTPDYQDVLFKKGFGGIIKEAKE 182

Query: 200 QFTSLQA---------DLENGVNL--EQTIRLRE-------EIAEQHRAL---GQMKEMA 238
               L           D  N + +  E  I L         E+A+        G++ ++A
Sbjct: 183 HIIKLSLTSAEDMKKKDFYNSIIITSEGMITLANRYGQKATEMADIENNPIRKGELLKIA 242

Query: 239 AKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKIT 298
              G     P     EAIQ+ +F  +  + S+N  A++ GR   F+  Y + D+  G IT
Sbjct: 243 DICGRIPENPPDTFYEAIQFVWFTQVGGIISENPLALNIGRFDQFMYPYYKSDVDKGIIT 302

Query: 299 EQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFL 358
           + EAQE+++ L +KL    +  +    E F+G   +   ++GG   +G+      S+  L
Sbjct: 303 KDEAQELIEALWIKLSEWVWTISANTAEFFAGYNQFQNLTVGGKTREGKDATNDLSYMCL 362

Query: 359 NTLYTMGPSPEPNMTILWSEKLPLNFKKFAAK-VSIDTSSLQYENDDLMRPDF------- 410
                +  + +P +++   +  P +F       VS  T      ND              
Sbjct: 363 KATERV-KTHQPGLSVRVHQDSPRSFLDAVTHLVSKGTGFPAIHNDTAGYQMLINAGYEP 421

Query: 411 -NNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGD 469
            +  D+    CV P              N    + +A+N G       ++G   +     
Sbjct: 422 EDARDWNNCGCVVPHFRKTGEWTSAVNINFTAALEFALNQGESRITGEKIGMDEDKPTT- 480

Query: 470 VLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIA- 528
             +Y+EV +      D L +  I A  +   +H +      L +  +  +I+      A 
Sbjct: 481 FQSYEEVEKAFYKQFDNLIEHSIIATLLAQKLHKEMVPRPFLSSCIEECMIKGKDLVDAG 540

Query: 529 ------------GLSVAADSLSAIK---YAKVKPIRDEDGLAIDFEIEG---------EY 564
                       GL+V ++SL+ IK   +       +    A+D   EG           
Sbjct: 541 AKYNLGPVLTGIGLAVTSNSLAVIKKLVFEDKMTTMETLIKALDANWEGYEKLRQLAVSV 600

Query: 565 PQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGR 624
           P++GNN   VDD+A+ +   + K+  K           + + I++ +  GK  G TP GR
Sbjct: 601 PKYGNNVDYVDDIAIKIANYYYKQGHKYKDINGNNFNTAFMGISNYLPTGKVVGATPCGR 660

Query: 625 RAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKT 684
           +A  P   G +P  G D    + ++ S AKL       G      +  + +       ++
Sbjct: 661 KAKEPLSEGVSPFAGSDTSTPLEAMRSAAKLNQDVHSGGTLLNLRLNEDLVNTKRG--QS 718

Query: 685 NLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLT 744
           NL  ++  +F       G  H+  N ++ + L  A  NP+ Y  L +RV+GY+ +F +L+
Sbjct: 719 NLGFMIQSFFAL-----GAFHVQFNTISTDTLRKAQNNPQDYKDLLVRVAGYSTQFVNLS 773

Query: 745 KEQQQDVITRTFTQ 758
           K  Q+ +I RT  +
Sbjct: 774 KSMQEAIIARTAHE 787


>UniRef50_P32674 Formate acetyltransferase 2 n=80 Tax=Gammaproteobacteria
           RepID=PFLD_ECOLI
          Length = 765

 Score =  566 bits (1460), Expect = e-160,   Method: Composition-based stats.
 Identities = 156/730 (21%), Positives = 290/730 (39%), Gaps = 87/730 (11%)

Query: 92  KQLEKIVGLQTEAPLKRALIPF-GGIKMIEGSCKAYNRELDPMI----------KKIFTE 140
           +  E I G +T  P    + P      +++   +   R  D             +++F  
Sbjct: 59  RDEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPY 118

Query: 141 Y-RKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKL- 198
           + +++    +    T ++     + + +      G+G II DY R+  +G+  L+     
Sbjct: 119 WEKRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQ 178

Query: 199 -----AQFTSLQADLENGVNLEQTIRLREEIAE-------QHRALGQMKEMAAKYGYDIS 246
                 +    QA L      ++ I    E+AE         +   ++  +A    ++  
Sbjct: 179 HCQQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQ 238

Query: 247 GPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMV 306
                  +A Q  ++  +      N +++S GR   ++  + +  L  G+      +E++
Sbjct: 239 HKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGE-DAAFLKELL 297

Query: 307 DHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGP 366
           + L +K   +  LR+      F+G P   T  +GG+  +GR+ V   SF  L+  Y    
Sbjct: 298 ESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDA-YQSVQ 356

Query: 367 SPEPNMTILWSEKLPLNF-KKFAAKVSIDTSSLQYENDDLMRPDF--------NNDDYAI 417
            P+PN+ +  +  +   F  K A  +   T   Q  ND+++ P F        +  DY++
Sbjct: 357 LPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSV 416

Query: 418 ACCVSPMIVGKQMQFFG-ARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEV 476
             CV   I G+       A  NL K M   ++               E      L Y+ +
Sbjct: 417 VGCVELSIPGRTYGLHDIAMFNLLKVMEICLH---------------ENEGNAALTYEGL 461

Query: 477 MERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRT-------------- 522
           +E++   +       +   NI    H  ++    L +     + +               
Sbjct: 462 LEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSG 521

Query: 523 -MACGIAGLSVAADSLSAIKYAKVKPIRDE------------DGLAIDFEIEGEYPQFGN 569
               GIA LS +  +L  + + + +   DE            +G  +   +   + ++GN
Sbjct: 522 VQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGN 581

Query: 570 NDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAP 629
           +   VD+++ +L+  + K+++K    R    T    T++++V  G   G TPDGR AG  
Sbjct: 582 DIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQ 641

Query: 630 FGP-GANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAG 688
               G +PM G+D +G  A L SV+KL      +G        P  L  +  +RK  LA 
Sbjct: 642 LADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRK--LAD 699

Query: 689 LMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQ 748
            +  +   +      QH+  NV+N + L +A + P+ Y  L +RV+GY+  F  L+KE Q
Sbjct: 700 FLRAFTQLKL-----QHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQ 754

Query: 749 QDVITRTFTQ 758
            D+I RT  Q
Sbjct: 755 DDIIRRTAHQ 764


>UniRef50_C0W9F6 Formate C-acetyltransferase n=1 Tax=Acidaminococcus sp. D21
           RepID=C0W9F6_9FIRM
          Length = 805

 Score =  564 bits (1453), Expect = e-159,   Method: Composition-based stats.
 Identities = 160/742 (21%), Positives = 286/742 (38%), Gaps = 99/742 (13%)

Query: 95  EKIVGLQTEAPLKRALIPFGGIK--------MIEGSCKAYNRELDPMI-----KKIFTEY 141
           E +VG            P  GI         + +       R  DP       KK++TE 
Sbjct: 74  ELLVG-------GVGFKPRCGILNPDSASGVIAKELDTISTRPFDPFYLSEEGKKVYTEK 126

Query: 142 RKTH--NQGVFDVYT----PDILRCRKSG-VLTGLPDAYGRGRIIGDYRRVALYGIDYLM 194
            + +  N+ VFD +      D  R R +G +        G G     + R+   G+  + 
Sbjct: 127 VQNYWKNKCVFDRWNLMLPEDAKRLRANGAIFIDRKAVRGYGENTPGWMRILTKGLAAIR 186

Query: 195 KDKLAQFTSLQADLENGVNLEQTIRLREE---------IAEQHRALGQ------------ 233
           K+       L  D  N  +LE++   + E         +A +H  L +            
Sbjct: 187 KEAEDALAKL--DDANPGDLEKSFFYKAEIKAADAVILLAHRHADLAEKMAAECDDPVRK 244

Query: 234 --MKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERD 291
             + ++A    +    PA    EA Q       A    QN ++ + GR   +L  Y ++D
Sbjct: 245 AELLKIAEVTRHVPEYPARTFYEACQSIISYEYACFMEQNASSYNLGRLDQYLYPYYKKD 304

Query: 292 LKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVT 351
            +AG +T+ +AQE++D L +K+  +   +     +  +G  I    S GG+   G     
Sbjct: 305 KEAGILTDDDAQELLDCLWIKVAEMSLFQDEVTAQYAAGYCITVQTSCGGIDQYGNDASN 364

Query: 352 KNSFRFLNTLYTMGPSPEPNMTILWS-EKLPLNFKKFAAK-VSIDTSSLQYENDDLMRPD 409
           + S+  +     +    EPNM + +S  K P +  + A + + +  +     ++D+    
Sbjct: 365 ELSYMMIQATEDV-RFKEPNMAMTYSISKNPDSLLRKAIESIGMGLTMPAIYSNDVGIQM 423

Query: 410 FNND--------DYAIACCVSPMIVGKQMQFFG-ARANLAKTMLYAINGGVDEKLKMQVG 460
             N         ++    CV   + GK  Q+   A  N+   + +A+N G       QV 
Sbjct: 424 LQNKGIPLREAWNWNPCGCVETNLSGKMKQYTDIADINMGAMVEFALNDGKSRITGEQVS 483

Query: 461 PKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVI 520
             +   + +   +D+    +   +D+     ++   ++ Y+   Y    +L   ++  + 
Sbjct: 484 IHTGDPR-NFKTFDDFFAAVKKHIDYAVDVIVSCNQLLDYLSMNYRPVPTLSLSYEHCME 542

Query: 521 --------------RTMACGIAGLSVAADSLSAIKY---AKVKPIRDEDGLAIDFEIEG- 562
                                 G +   +S++ +KY    + K   D    A+D   EG 
Sbjct: 543 VGKDYSQPGGAQYNAGGGVITVGQADIINSIADVKYLVFDEKKISMDTLIKALDANFEGY 602

Query: 563 --------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYG 614
                   E P++GN+DPR D    ++      + +K  T    + T  +L ++ N   G
Sbjct: 603 EDIQKLCLEAPKYGNDDPRADFCVGEIFNHVADQFEKYDTVFGKM-TLGMLPVSGNTPIG 661

Query: 615 KKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNA 674
           +  G  P GR+A  P   G     G D  G  A L SV+ LP A    G        P+ 
Sbjct: 662 QWVGALPSGRKATTPLTDGIGATGGTDVNGPTALLKSVSHLPHARFTQGTQLNMKFEPDL 721

Query: 675 LGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVS 734
           +  ++ +  T+   ++        S+ G  H  +N ++RE L+DA ++P  +  L IRV+
Sbjct: 722 IKGENGM--THAMNMVKT-----MSVLGVYHAQINCVDRETLIDAQKHPNDHRDLLIRVA 774

Query: 735 GYAVRFNSLTKEQQQDVITRTF 756
           GY   F  L KE Q ++I RT 
Sbjct: 775 GYTAFFVELGKETQDEIIGRTE 796


>UniRef50_B5XXR3 Formate C-acetyltransferase 2 n=9 Tax=cellular organisms
           RepID=B5XXR3_KLEP3
          Length = 765

 Score =  562 bits (1448), Expect = e-158,   Method: Composition-based stats.
 Identities = 161/733 (21%), Positives = 297/733 (40%), Gaps = 93/733 (12%)

Query: 92  KQLEKIVGLQTEAPLKRALIPF-GGIKMIEGSCKAYNRELDPMI----------KKIFTE 140
           ++ E I G +T  P    + P      ++        R  D             + ++  
Sbjct: 59  REDELIAGNRTVKPRAGIMSPEMDPYWLLNELDAFPTRPQDRFAISEEDKQIYREALYPY 118

Query: 141 Y-RKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKD--- 196
           + +++    +    T ++     + + +      G+G II DY R+  +G+  L+ +   
Sbjct: 119 WEKRSMKDFINGQMTEEVKAAVNTQIFSVNQTDKGQGHIIIDYPRLLNHGLGALVAELKT 178

Query: 197 ---KLAQFTSLQADLENGVNLEQTIR-------LREEIAEQHRALGQMKEM---AAKYGY 243
              +  +    QA L   + LE + R       L EE+A   +   + +E+   AA   +
Sbjct: 179 HCARQPENPFYQAVL---ILLEASQRHILRYAALAEEMAGHFQDPQRQQELLTIAAISRH 235

Query: 244 DISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQ 303
           +     T+  +A Q  ++  +      N +++S GR   ++  + +  L  G+      +
Sbjct: 236 NAQHRPTDFPQACQLFWYMNIILQYESNASSISLGRFDQYMLPFYQASLNQGQ-DPAYLK 294

Query: 304 EMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYT 363
           E+++ L +K   +  LR+      F+G P   T  +GG+   GR+ V + SF  L+    
Sbjct: 295 ELLESLWVKCNDIVLLRSSSSARYFAGFPTGYTALLGGLTDTGRSAVNELSFLCLDAYQN 354

Query: 364 MGPSPEPNMTILWSEKLPLNFKKFAAK-VSIDTSSLQYENDDLMRPDF--------NNDD 414
           +   P+PN+ +  +E +   F +  A+ + + T   Q  ND+++ P F        +  D
Sbjct: 355 V-QLPQPNLGVRVNELIDRPFLRKTAETIRLGTGIPQIFNDEVVVPAFLNRGVSLEDARD 413

Query: 415 YAIACCVSPMIVGKQMQFFG-ARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNY 473
           YA+  CV   I G+       A  NL K M   +              +    + DV  +
Sbjct: 414 YAVVGCVELSIPGRTYGLHDIAMFNLLKVMEIVL--------------QENEHQPDVT-W 458

Query: 474 DEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTM---------- 523
           D ++ ++   +    K  +   NI    H  ++    L +  +  V              
Sbjct: 459 DGLICQIRDKIRHYIKLMVEGSNICDIGHRDWAPVPLLSSFIEDCVQHGKDITAGGARYN 518

Query: 524 --ACGIAGLSVAADSLSAIKYAKVKPIRDE---------------DGLAIDFEIEGEYPQ 566
                  G++  +DSL A+K       R                 +G  I   +   + +
Sbjct: 519 FSGVQGIGIANLSDSLYALKGMVFDQQRLSFDQLMAVLKANFQTPEGEKIRARLINHFDK 578

Query: 567 FGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRA 626
           +GN+   VD+++ DL+  + K++++    R    T    T++++V  G   G TPDGR A
Sbjct: 579 YGNDIDDVDNISADLLRFYCKEVEQYLNPRGGHFTPGSYTVSAHVPLGSVVGATPDGRLA 638

Query: 627 GAPFGP-GANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTN 685
           G      G +PM G+D +G  A L SV+KL      +G        P  L  D  + K  
Sbjct: 639 GEQLADGGLSPMVGQDSQGPTAVLKSVSKLDNYLLSNGTLLNVKFTPATLAGDGGLNK-- 696

Query: 686 LAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTK 745
           LA  +  +   +      QH+  NV+N + L +A + P+ +  L +RV+GY+  F  L+K
Sbjct: 697 LADFLQAFCKLKL-----QHIQFNVVNADTLREAQQRPQDFAGLVVRVAGYSAFFVELSK 751

Query: 746 EQQQDVITRTFTQ 758
           E Q D+I RT  Q
Sbjct: 752 EIQDDIIRRTAHQ 764


>UniRef50_A6TKL5 Pyruvate formate-lyase n=1 Tax=Alkaliphilus metalliredigens QYMF
           RepID=A6TKL5_ALKMQ
          Length = 806

 Score =  557 bits (1435), Expect = e-157,   Method: Composition-based stats.
 Identities = 160/693 (23%), Positives = 284/693 (40%), Gaps = 68/693 (9%)

Query: 128 RELDPMIKKIFTEYR-KTHNQGVFDVYTPDILRCRKSGVLT-GLPDAYGRGRIIGDYRRV 185
           + +   +K IF  +R KT +     +   +  R R + + T GL +  G G    D  ++
Sbjct: 122 KNVKEDLKDIFPYWRGKTIHDRYRAMLPDETKRARDAYMFTRGLFEQNGYGHTAYDIPKL 181

Query: 186 ALYGIDYLMKDKLAQFTSLQADLENG------------------VNLEQTIRLREEIAEQ 227
              G+  +  +   +  +L      G                     ++  +   E+A+Q
Sbjct: 182 LKVGLVGIKSEVNEKMQTLDLTTSEGLEKKLFYEGLIVCCDSVIAYAKRYAQRALELADQ 241

Query: 228 HRAL---GQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFL 284
            +      +++++A    +    PA +  +AIQ   F  L      NG ++  GR   +L
Sbjct: 242 EKNPVRKKELEKIADVCQWVPENPARDTWDAIQVVAFMQLIIQTETNGDSVCPGRLDQYL 301

Query: 285 DVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGL 344
             Y + D+  G+ T  E QE++D L +KL  +  ++  E   +  G P+  T +IGG   
Sbjct: 302 YSYYKNDMAEGRYTIDEIQELLDCLWIKLNEIIKIQASESVRIHPGFPMTPTVTIGGQTP 361

Query: 345 DGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNF-KKFAAKVSIDTSSLQYEND 403
           +G     + S+  LN+   +     P  T+ + +  P +F  +    V + T       D
Sbjct: 362 EGEDATNELSYLMLNSQEHI-RLTNPQFTVRFHKDTPEDFKLRVVEVVKLGTGMPAMFGD 420

Query: 404 DLMR----------PDFNNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDE 453
           +             P     DY I  CV     G Q +  G   N+A+ +  A+N GVD 
Sbjct: 421 EACIAALKRGCPDMPMERIRDYRIVGCVELAPRGFQGRVNGGFLNVARVVDLALNNGVDR 480

Query: 454 KLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMA 513
               Q+GP++   + D+ ++D+V+  +     +  K  +    ++  +  +++    L +
Sbjct: 481 LTNEQIGPQTGAPE-DLKDFDDVLTAVRTQTAYFVKHQVINAAVVDMVQREHTPHLFLSS 539

Query: 514 LHDRDVIRTM------------ACGIAGLSVAADSLSAIKYAKVKP---IRDEDGLAIDF 558
           L +  +                     G + AADSL  +K A          E    +D 
Sbjct: 540 LVEGCIENGKDMTQGGSLWGGTPILHVGEATAADSLIGVKKAVFDDQLISMKELKEILDS 599

Query: 559 EIEG-----------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTI 607
              G             P++GN+D   D++   ++  F  +I+K         T ++LT+
Sbjct: 600 NFAGAQGEKIYQALLAMPKYGNDDDYADEVMQKMINIFFDEIEKHKDIDGRFYTSTILTL 659

Query: 608 TSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYT 667
            + V +G  TG T +GR+A  P     +  +G D++G  A L S +K+      +G    
Sbjct: 660 GATVPHGWTTGATANGRKATMPVADSMSASNGADKEGPTAMLLSASKIDQTRTIEGNVVN 719

Query: 668 FSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYP 727
                 AL +   +++  L  L+  YF        GQ + VNV++   L DA E PEK+ 
Sbjct: 720 LKFTKMALEEKKNLQQ--LVNLVSVYFDDLK----GQEIQVNVVDESTLKDAQEYPEKHQ 773

Query: 728 QLTIRVSGYAVRFNSLTKEQQQDVITRTFTQSM 760
            L IRV+GY+ RF  L KE Q D+I RT   ++
Sbjct: 774 DLIIRVAGYSARFTELAKELQDDIIRRTEYNTL 806


>UniRef50_Q1A666 Glycerol dehydratase n=8 Tax=Clostridiales RepID=Q1A666_9FIRM
          Length = 843

 Score =  549 bits (1414), Expect = e-154,   Method: Composition-based stats.
 Identities = 180/789 (22%), Positives = 293/789 (37%), Gaps = 137/789 (17%)

Query: 90  INKQLEKIVGLQTEAPLKRALIPFGGIKMIE-GSCKAYNRELDPMI------KKIFTE-- 140
           I +  E IVG  T AP      P    + +E        R  DP        K++     
Sbjct: 67  IIRPEELIVGSTTIAPRGCQTYPEFSYEWLEAEFETVETRSADPFYISEETKKRLLAADA 126

Query: 141 -YRKTHNQGVFDVYT-PDILRCRKSGVLTGLPDAY-GRGRIIGDYRRVALYGIDYLMKDK 197
            ++      +   Y  P+ LR  K    T     Y G G +   Y  V   G++ + +  
Sbjct: 127 YWKGKTTSELATSYMAPETLRAMKHNFFTPGNYFYNGVGHVTVQYETVLAIGLNGVKEKV 186

Query: 198 LAQ-----------------FTSLQADLENGV-NLEQTIRLREEIAEQHRALGQMKEM-- 237
             +                   S+    +  +    +  ++ EE+AE+     + +E+  
Sbjct: 187 RKEMENCHFGDADYSTKMCFLESILISCDAVITYANRYAKMAEEMAEKETDAARRQELLT 246

Query: 238 -AAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGK 296
            A         PA + QEA Q  +F         +G ++S GR   ++  Y E+DLK G 
Sbjct: 247 IARVCKNVPEFPAESFQEACQSFWFIQQVLQIESSGHSISPGRFDQYMYPYYEKDLKEGS 306

Query: 297 ITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFR 356
           +T + AQE++D + +KL  +   R     E F+G  ++    +GG  + GR      SF 
Sbjct: 307 LTREYAQELIDCIWVKLNDLNKCRDAASAEGFAGYSLFQNLIVGGQTVQGRDATNDLSFM 366

Query: 357 FLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSI-DTSSLQYENDDLMRPDF----- 410
            +     +   P P+++I             AA+++        Y ND+++ P       
Sbjct: 367 CITASEHVF-LPMPSLSIRVWHGSSKALLMRAAELTRTGIGLPAYYNDEVIIPALVHRGA 425

Query: 411 ---NNDDYAIACCVSPMIVGKQMQFF-GARANLAKTMLYAINGGVDEKLKMQVGPKSEPI 466
                 +Y I  CV P + GK   +   A  N+ + +    + G D         ++  +
Sbjct: 426 TMDEARNYNIIGCVEPQVPGKTDGWHDAAFFNMCRPLEMVFSNGYDN--GEIASIQTGNV 483

Query: 467 KGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMAC- 525
           +    ++DE ME     M +  +  + A N I Y H K +       L D  + R M+  
Sbjct: 484 ES-FQSFDEFMEAYRKQMLYNIELMVNADNAIDYAHAKLAPLPFESCLVDDCIKRGMSAQ 542

Query: 526 -GIA----------GLSVAADSLSAIK---YAKVKPIRDEDGLAIDFEIEGEYPQFGNND 571
            G A          G++  ADSL  IK   + + +    E   A++    G+    G + 
Sbjct: 543 EGGAIYNFTGPQGFGIANVADSLYTIKKLVFEEKRITMGELKKALEMN-YGK----GLDA 597

Query: 572 PRVDDLA-----------------------------------VDLVERFMKKIQKLH--- 593
               D+A                                       E   + I +L    
Sbjct: 598 TTAGDIAMQVAKGLKDAGQEVGPDVIANTIRQVLEMELPEDVRKRYEEIHEMILELPKYG 657

Query: 594 -------------------------TYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGA 628
                                      R  +    +  +++NV  G +TG TPDGR A  
Sbjct: 658 NDIDEVDELAREAAYFYTRPLETFKNPRGGMYQAGLYPVSANVPLGAQTGATPDGRLAHT 717

Query: 629 PFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAG 688
           P   G  P  G D  G  AS  SVAKL  A A +G  +   + P A+  +  +   +   
Sbjct: 718 PVADGVGPTSGFDISGPTASCNSVAKLDHAIASNGTLFNMKMHPTAMAGEKGLE--SFIS 775

Query: 689 LMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQ 748
           L+ GYF  +     G H+  NV++R  LLDA  +PEKY  L +RV+GY+  F +L+K  Q
Sbjct: 776 LIRGYFDQQ-----GMHMQFNVVDRATLLDAQAHPEKYSGLIVRVAGYSALFTTLSKSLQ 830

Query: 749 QDVITRTFT 757
            D+I RT  
Sbjct: 831 DDIIKRTEQ 839


>UniRef50_C0QGR8 PflD1 n=1 Tax=Desulfobacterium autotrophicum HRM2
           RepID=C0QGR8_DESAH
          Length = 788

 Score =  547 bits (1410), Expect = e-154,   Method: Composition-based stats.
 Identities = 160/740 (21%), Positives = 290/740 (39%), Gaps = 86/740 (11%)

Query: 92  KQLEKIVGLQTEAPLKRALIPFGGIKMIE-----------------GSCKAYNRELDPMI 134
              E IVG +  AP      P      I+                  + K Y +++ P  
Sbjct: 63  GDEELIVGERGRAPKLIPTFPEIACHSIKDLKVLNSQNRIPYNVSPKTIKIYEKKVIPYW 122

Query: 135 K----------KIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRG-----RII 179
                      ++  E++  +N G+      + +  R  G +      +G G     + I
Sbjct: 123 DGAALRDRMFNQLSDEWQTIYNCGLI----TETMEQRAPGSMALDERMFGMGLKKAKQEI 178

Query: 180 GDYRRVALYGIDYLMKDKLAQFTSLQADLENG-VNLEQTIRLREEIAEQ---HRALGQMK 235
            +  +   +  D+   DK  Q T++    +   +  ++   + E+ + +    +   + +
Sbjct: 179 EEAIKNLDFLNDFEAIDKREQLTAMAITCDGMMIYAKRYADMLEKKSSEETNKKRKKEFE 238

Query: 236 EMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNG-AAMSFGRTSTFLDVYIERDLKA 294
           +MA       +    +  E +Q ++F ++  +   NG  A + G        Y ++ L+ 
Sbjct: 239 KMADVCRNVPANKPRDLWEVLQMSWFMHIGVITESNGWDACNPGHVDRHFFPYYKKSLET 298

Query: 295 GKITEQEAQEMVDHLVMKLRM-VRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKN 353
           G++ E+ A+E++    +K        +             +   S+GG+  DG+  V   
Sbjct: 299 GQLDEESAKELLCAWWIKYNNHPAPAKYGVSALESGTYNDFVNISLGGITTDGKDAVNDL 358

Query: 354 SFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKV-SIDTSSLQYENDDLMRPD--- 409
           S+ FL  L  +    +P + +L S   P +F K A KV           N + +      
Sbjct: 359 SYIFLEILDEIE-FIQPQVHVLLSRMNPEHFLKEACKVIRKGRGFPAMFNAEAVIEQQLR 417

Query: 410 -----FNNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSE 464
                 +     I  CV     GK+        N+AK +   +  G D + K QVGPK+ 
Sbjct: 418 VGKTISDARGGGICGCVETTCYGKEAAPLIGYINIAKILELTLQNGFDTRTKKQVGPKTG 477

Query: 465 PIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMA 524
            +K D  +Y+E+ME       ++    +     +  M  KY  +  L  L +  V     
Sbjct: 478 NVK-DFNSYEELMEAFKKQARYIIDTKLVGSQYLIQMFAKYVPQPFLSVLIEGCVESGKD 536

Query: 525 ------------CGIAGLSVAADSLSAIKYAKV---KPIRDEDGLAIDFEIE-------- 561
                           G+    DSLSAIK            E   A++ + +        
Sbjct: 537 YNDGGPKYNVSILPGVGIGTVTDSLSAIKKHVFDESTYSMGEVIEALNADWQKSEEMRLT 596

Query: 562 --GEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGN 619
              + P++GN++   D +  ++ + F+  +  +   R      ++L  T ++ +G+ TG 
Sbjct: 597 FANKTPRYGNDNDYADSIMREVSDFFIDTVDGIKDSRGGTYRMNMLPTTCHMYFGEVTGA 656

Query: 620 TPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDD 679
           T DGRRAG P   G +P+ G D  G  ASL S AK+  +    G       +P+ L  D 
Sbjct: 657 TCDGRRAGKPLSEGISPVQGADLCGPTASLKSAAKMDHSRTC-GTLLNMKFLPDVLKGDI 715

Query: 680 EVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVR 739
            + K  LA L+  YF +     GG H+  NV + + L  A + PE Y  L +RV+GY+  
Sbjct: 716 GIHK--LASLIRTYFTY-----GGHHIQFNVCDAKTLQLAQKTPEDYNDLIVRVAGYSDY 768

Query: 740 FNSLTKEQQQDVITRTFTQS 759
           FN++ K+ Q ++I R   ++
Sbjct: 769 FNAIGKDLQDEIIQRYAHEA 788


>UniRef50_D1ARQ1 Pyruvate formate-lyase n=3 Tax=Bacteria RepID=D1ARQ1_SEBTE
          Length = 807

 Score =  540 bits (1390), Expect = e-151,   Method: Composition-based stats.
 Identities = 167/742 (22%), Positives = 288/742 (38%), Gaps = 83/742 (11%)

Query: 89  YINKQLEKIVGLQTEAPLKRALIPFGGIK-MIEGSCKAYNRELDPMI--------KKIFT 139
           YI + +  I+G Q  +     + P      +I    +   R  D            ++  
Sbjct: 71  YIEEGM-LIIGNQASSNFAAPIFPEYSFNWVINELDEFSKRSGDYFNITEETKDRLRVLQ 129

Query: 140 EYRK--THNQGVFDVYTPDILRCRKSGVLT-GLPDAYGRGRIIGDYRRVALYGIDYLMKD 196
           +Y +  TH   V         +  + GVL  G     G G II ++  V   G   L + 
Sbjct: 130 DYWQGITHQDNVLHNLPEINRKAEEQGVLHRGGISMSGDGHIIPNHDLVLAEGFGGLARI 189

Query: 197 KLAQFTSLQADLENGVNLEQTI-----------RLREEIAEQ------HRALGQMKEMAA 239
                       E     E              R  E  A +       +   ++K+++ 
Sbjct: 190 AEENSKREGLTQEQKDFYEAVKITMNAALKYIKRFSELAAREAEKETDEKRKNELKDLSK 249

Query: 240 KYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITE 299
            + + + G A +  EA++  Y  +L  +   NG + SFGR   ++  Y + D+ +GKI++
Sbjct: 250 MFAHLMEGKAESFHEAVEAVYLTHLLMMIESNGHSFSFGRFDQYIYPYYKADIDSGKISK 309

Query: 300 QEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLN 359
           ++A E++ H  +    +  +R   + +   G P+++   +GGM  DG       S+  L 
Sbjct: 310 EKALEIITHFFLMTNSLNKVRPWGHTQYSGGYPLYSNLIVGGMKPDGSEGTNDISYLCLE 369

Query: 360 TLYTMGPSPEPNMTILWSEKLPLNFKKFAAK-VSIDTSSLQYENDDLMRPDFN------- 411
            +  +   PEPN+++ + E+ P +  K +A+ +           D+++ P          
Sbjct: 370 AM-NLSRLPEPNLSVRFCEETPRSLLKDSARLIRKGFGMPSLFCDEVVIPAMMTLDLDIE 428

Query: 412 -NDDYAIACCVSPMIVGK--QMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKG 468
              DYA   CV   I GK           N  K +   +N G+D    +Q+   +     
Sbjct: 429 TARDYASMGCVETAIPGKWGHRATGMTYINFGKILELIMNNGMDPASGIQLFSITGKNDR 488

Query: 469 --DVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACG 526
             D  +YDE+ +  +  + + +   +    +       +  +A   A  +  + R     
Sbjct: 489 NIDFKSYDELWKAWETALKFYSDLAVDCDLVCDRSLKHFDADAFASATINCSLERGKTLK 548

Query: 527 IAGL------------SVAADSLSAIKYAKVKP---IRDEDGLAIDFEIEG--------- 562
             G             SV  DSL+A+K            +   A+D   EG         
Sbjct: 549 NGGAEYDYVSQSNIGPSVVGDSLAAVKKLVFDDKVITMKQLRDAMDTNFEGIEGAKIRKL 608

Query: 563 --EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHT------YRDAIPTQSVLTITSNVVYG 614
             + P+FGN+   VD++  D+ E ++  +   HT       +    T S   ITS V  G
Sbjct: 609 CRQAPKFGNDIDYVDNIVADVYESYLALLPNYHTDRYGCGPKGCGYTMSTSNITSYVPNG 668

Query: 615 KKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNA 674
              G TPDGR AG P   GA+P  G D++G  A + SV+KLP      G        P A
Sbjct: 669 FDVGATPDGRFAGKPLNEGASPCLGADKEGPTAVINSVSKLPNKKIAGGQLLNMRFAPGA 728

Query: 675 LGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVS 734
           L  ++ + K      ++      A  +   H   N+++   L  A ENPE++  L +RV+
Sbjct: 729 LAGEENLEK--FVSFIEA-----ARYKNIFHNQFNIVDGATLKAAKENPEEHADLMVRVA 781

Query: 735 GYAVRFNSLTKEQQQDVITRTF 756
           GY   F++L  E Q  +I RT 
Sbjct: 782 GYCALFSTLMPEAQDAIIERTE 803


>UniRef50_C0C5J5 Putative uncharacterized protein n=1 Tax=Clostridium hylemonae DSM
           15053 RepID=C0C5J5_9CLOT
          Length = 797

 Score =  536 bits (1382), Expect = e-151,   Method: Composition-based stats.
 Identities = 162/739 (21%), Positives = 296/739 (40%), Gaps = 83/739 (11%)

Query: 93  QLEKIVGLQTEAPLKRALIPFGGIKMI-EGSCKAYNRELDPMI-----KKIFTEYRKTHN 146
           + E IVG          L       ++ +       R+ DP       K++F +  K   
Sbjct: 64  EKELIVGCAGSKMRGGILSADTCWSILDKELETINERQYDPFYLRPEDKQMFLDVIKPFW 123

Query: 147 QG--VFDVYTPDI----LRCRKSG-VLTGLPDAYGRGRIIGDYRRVALYGIDYLMK---- 195
           +G   ++ +   I       R +G V        G G     Y ++   GI+ +M     
Sbjct: 124 EGRSTYEAWLKQIPEDCRNLRDTGQVYIDKKAVRGWGETTVGYTQIINEGIESIMDTVKA 183

Query: 196 -------------DKLAQFTSLQADLENG-VNLEQTIRLREEIAEQHRALG---QMKEMA 238
                        DK     +L    E   +  ++     + +A +        ++  +A
Sbjct: 184 EREALDLTEPGAIDKDNYLQALLISAEGICMMAKRYADEADRLAAEEEDAERRSELLTIA 243

Query: 239 AKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKIT 298
                    PA + QEA+Q  YF +++    QN AA + GR   +L  Y + DL+ G IT
Sbjct: 244 RTCRRVPRYPARSFQEALQSFYFYHISIFMEQNAAAYNPGRMDQYLYPYYKSDLEEGTIT 303

Query: 299 EQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFL 358
           E+E  E+++ L +K       +        +G P++ T   GG+  +G   V   S+  L
Sbjct: 304 EEEGLELLECLWVKFAEPCVFQDATTARYSAGYPMFQTLCCGGIDSEGNDAVNDVSYMML 363

Query: 359 NTLYTMGPSPEPNMTILWS-EKLPLNFKKFAAKV-SIDTSSLQYENDDLMRPDFNND--- 413
                +    +PN+T+ +S  K P  F K  A+V S+ T    + NDD+      N    
Sbjct: 364 QATEDV-QLYQPNLTVRYSMAKNPNRFLKKIAQVISLGTGFPAFHNDDVGIRMLMNKGIP 422

Query: 414 -----DYAIACCVSPMIVGKQMQFFG-ARANLAKTMLYAINGGVDEKLKMQVGPKSEPIK 467
                D+  A CV   + G+   +   A  NL   + +A+  GV+ K   +V  ++    
Sbjct: 423 LKEAFDWNPAGCVETNLEGRLRHYSAFADINLGGMIEFAMTNGVNRKSGRKVSAETGDPA 482

Query: 468 GDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIR------ 521
                Y +    +   + +  +  +   ++I  +       A  ++L  R+ +       
Sbjct: 483 S-FTEYGDFEHAVKEQLKFSIQACVKGSHVIDDICMDRVVPA--LSLSFRECVEQAKDYA 539

Query: 522 -----------TMACGIAGLSVAADSLSAIKYAKVKPIRDEDGLAIDFEIEG-------- 562
                       +  G+A L  + +++  + Y K     ++   A++ + EG        
Sbjct: 540 WGGAKYNAGNGIILIGVADLINSMEAVKELVYEKKLVSMEDMVNALNADFEGYEEIRELC 599

Query: 563 -EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTP 621
            +  ++GN+D  V+++A  ++     +I++ H+    + T  +L ++ N  +G+  G  P
Sbjct: 600 QKCRKYGNDDEEVNEIASHMLTFIADEIEQYHSKFGQM-TPGILPVSGNTPFGQDVGALP 658

Query: 622 DGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEV 681
            GR+A  P   G +P  G D  G  A L S A +P A    G      + P+ +  ++ +
Sbjct: 659 SGRKAWTPLADGISPNGGTDVSGPAAVLKSAASIPHARYVQGTLLNMKLEPDMVKTENGI 718

Query: 682 RKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFN 741
           ++  L  L+           G  H+  NV++RE LL A + PE Y  L +RV+GY   F 
Sbjct: 719 QQ--LMALLKSLCTL-----GVYHVQFNVIDRETLLAAQKKPEDYRGLLVRVAGYTAYFT 771

Query: 742 SLTKEQQQDVITRTFTQSM 760
            L K+ Q ++I+RT   S 
Sbjct: 772 ELGKDVQDEIISRTAQSSF 790


>UniRef50_C7N778 Pyruvate-formate lyase n=1 Tax=Slackia heliotrinireducens DSM 20476
           RepID=C7N778_SLAHD
          Length = 789

 Score =  531 bits (1369), Expect = e-149,   Method: Composition-based stats.
 Identities = 144/737 (19%), Positives = 276/737 (37%), Gaps = 79/737 (10%)

Query: 93  QLEKIVGLQTEAPLKRALIPF--GGIKMIEGSCKAYNRELDPMI---------KKIFTEY 141
             E IVG  T A     L P        I    +   R  DP                 +
Sbjct: 61  DDELIVGTATNAYRGANLHPEFQSSSWYISDIDEFQTRTKDPYYISAEDRETILATLPYW 120

Query: 142 RKTHNQGVFDVYTPD-ILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQ 200
                + V +   P  I       +L    +    G    D+ ++   GI   + +    
Sbjct: 121 EGKAMEDVAEEAMPAYIKELESDDILCVGLENGVSGETTCDHEKIMAVGIRGYIDECQRN 180

Query: 201 FTSLQADLENG-----------VNLEQTIRLREEIAEQHRALG----------QMKEMAA 239
             ++                  +  E  I     +A++   L           ++++MA 
Sbjct: 181 IDAIVPQTMEDQAKVDFWKACIIQSEGLITYAHRMADEADRLADACDDPVRAAELRQMAE 240

Query: 240 KYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERD-LKAGKIT 298
                   P     +A Q  +F ++A        A+ FGR   ++  + ++D +    IT
Sbjct: 241 NCRVVPENPPQTFWQACQMVWFIHVAFYIEVCTTAIGFGRFDQYMWPFYKKDVIDEKNIT 300

Query: 299 EQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFL 358
             +A E+++ L +K   V  +R   Y   F+G P+W    +GG   DG+      S   L
Sbjct: 301 RDQALEILESLYLKSCEVYEVRDSWYATSFAGYPMWQILVVGGQTRDGKDASNDLSMLCL 360

Query: 359 NTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSS-LQYEND-DLMRPDF------ 410
                +  + +P M +   +  P    +F  K++ +  +   + ND   M+         
Sbjct: 361 EAADAL-QTTQPVMALRVCDTTPEELIRFGCKMTQEGQANPGFFNDATAMKMALAKGGTL 419

Query: 411 -NNDDYAIACCVSPMIVGKQMQFF--GARANLAKTMLYAINGGVDEKLKMQVGPKSEPIK 467
            +  D+ I  C+     G            N+ K + + ++ GVD      +G ++   +
Sbjct: 420 EDARDWTIVGCIQAGPGGGGTDGSPDAGYVNMGKMIEFVLHDGVDPATGKLMGLRTGDPR 479

Query: 468 GDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACG- 526
            +  N ++  + +   +     Q     N++  +H           +    V    +   
Sbjct: 480 -EFKNIEQFKDALKKQIVHAYDQIRIGYNLMQSIHMNRYPVIFASMVTRGCVENGKSVQH 538

Query: 527 -----------IAGLSVAADSLSAIKYAKVKP---IRDEDGLAIDFEIEGEY-------- 564
                      + G +  ADS++A++    +      +E   A D   EG+         
Sbjct: 539 GGANVSTAGMYVTGAANLADSIAAVEKCVFEDHDLTMEELIRACDTNFEGQERLRQMLLN 598

Query: 565 --PQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPD 622
             P++GN+DP VD +  +++    + +Q+    R       + + T N+ +G+ TG  PD
Sbjct: 599 KPPKYGNDDPHVDAIYREMMHHIAETVQQWPDARGGHYAFGIDSQTMNLPHGQVTGALPD 658

Query: 623 GRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVR 682
           GR AG      ++PM GRD  G  +++ SVA +     ++G  +     P  +  +  + 
Sbjct: 659 GRLAGESLCDASSPMMGRDICGPTSTVKSVAAIDQDILQEGALFNLRFDPKGVQGEKGI- 717

Query: 683 KTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNS 742
              + G++  +F +     GG+H+ +NV++ + L+DA ++PE +  L +RV+GY   F  
Sbjct: 718 -DIIEGVVKTFFQN-----GGEHIQINVVDNDTLIDAQKHPELHRGLMVRVAGYMAYFTE 771

Query: 743 LTKEQQQDVITRTFTQS 759
           L K+ Q  +I RT   S
Sbjct: 772 LDKQAQDTIIRRTPHLS 788


>UniRef50_B8FA81 Formate C-acetyltransferase n=1 Tax=Desulfatibacillum alkenivorans
           AK-01 RepID=B8FA81_DESAA
          Length = 831

 Score =  531 bits (1367), Expect = e-149,   Method: Composition-based stats.
 Identities = 165/764 (21%), Positives = 305/764 (39%), Gaps = 86/764 (11%)

Query: 59  MEGVKLENRTHAPVDFDTA----VASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFG 114
           ME   L NR+  P   D      +   I  +  G   +  +K++  +     K A+ P  
Sbjct: 92  MELDFLLNRSRQPFSIDPDDRRELEEDILPYWRGRTVRDRKKVLWKENGLNFKPAVDP-- 149

Query: 115 GIKMIEGSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYG 174
                      Y R     ++KI    +       + +    +     +     +     
Sbjct: 150 --------LSLYKRHKSLDLQKIKKAAKVPGGDAAYAL--KGMKEILHNNPALVMNVFDV 199

Query: 175 RGRIIGDYRRVALYGIDYLMKD------------KLAQFTSLQADL----ENGVNLEQTI 218
           +G +I   + V   G   +M              K       ++ +       +  E+  
Sbjct: 200 QGHLILGIKNVLSQGFSGIMAQAEKGLAEAKEAGKADDAAFYESVMISCEAAKILAERLA 259

Query: 219 RLREEIAEQHRALGQMKEM---AAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAM 275
           +  EE A +     + +E+   A +  +    P     EA+Q  +   L  + S     +
Sbjct: 260 KKAEEAASEENDPDRQRELLAAAKRCRHSPWNPPRTFHEAVQAMWLILLGGLVSHGMVGI 319

Query: 276 -SFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKL----RMVRFLRTPEYDELFSG 330
            + GR   +L  Y ++D+++G+I +  A  +++ L++KL     ++ ++     +EL S 
Sbjct: 320 LAVGRLDQYLYPYYKKDVESGRIDQAMAVRLMEELLIKLGANLMILPYVGKNTGNELGSD 379

Query: 331 DPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAK 390
             +    +IGG+   G+  V   ++  L     +      + T+  S++ P  F + A +
Sbjct: 380 SCV---PTIGGVDAQGKDAVNPLTYAVLEAFANVKSLGN-SFTVRLSQESPPEFWQKALE 435

Query: 391 VSIDTSSLQYENDDLMRPDFNN--------DDYAIACCVSPMIVGKQMQ-FFGARANLAK 441
              +TS     ND+++ P   N         DY +  CV P   G       G   +L+ 
Sbjct: 436 TYRETSGAALFNDEIVTPALQNCGMTLEDARDYGVIGCVEPTGDGDAFGCTSGNDVSLSA 495

Query: 442 TMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYM 501
            +  A+  G    +   +GPK+   K     +D+V+E     ++++      A+N+   +
Sbjct: 496 ALEMALGDGYLRVMGKAIGPKTGNPK-KFKTFDQVLEAFKKQVEFMVDTVARAVNLKDQI 554

Query: 502 HDKYSYEASLMALHDR--DVIRTMACGIA----------GLSVAADSLSAIK---YAKVK 546
           + +  +   +        D  R M  G A          G+  AADSL+AIK   + +  
Sbjct: 555 YMEEYHNPYISCTLTGCLDNARDMTQGGAKYNFGSISGRGMGTAADSLAAIKCFVFDQKT 614

Query: 547 PIRDEDGLAIDFEIEG----------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYR 596
               +    +D   +G            P FG++DP  DD+A ++   F K +    T R
Sbjct: 615 FSMAKILKMLDCNFKGYDKERAMLAHRAPAFGSDDPYADDIAKEVCAFFCKTVASKQTLR 674

Query: 597 DAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLP 656
                 S  +   +V+ G   G TP+GR AG P     +P +G +++G    L SVAKL 
Sbjct: 675 GGPFRPSFFSYGVHVLEGLYIGATPNGRLAGTPVSNSLSPTNGSEKQGPTGVLGSVAKLD 734

Query: 657 FAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREML 716
            +   +G S    ++P+    ++ + K  + GL+ G+F       GG  +  NV++ + L
Sbjct: 735 HSLISNGSSVNIKLMPSMFQGEERLNK--MIGLVKGFF-----ASGGMEVQPNVVSNQTL 787

Query: 717 LDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQSM 760
           LDA ++PE Y  L +RVSGY+  F  L K  Q ++I RT  + +
Sbjct: 788 LDAQKHPENYRDLVVRVSGYSAFFTDLGKPIQDEIIQRTEFEGL 831


>UniRef50_B0G487 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=B0G487_9FIRM
          Length = 803

 Score =  528 bits (1360), Expect = e-148,   Method: Composition-based stats.
 Identities = 171/753 (22%), Positives = 291/753 (38%), Gaps = 95/753 (12%)

Query: 92  KQLEKIVGLQTEAPLKRALIPFGGIK-MIEGSCKAYNRELD---------PMIKKIFTE- 140
           K  E IVG   +      + P    + ++E       R  D         P  +KI  E 
Sbjct: 59  KPGELIVGNMAKNAKSSPVFPEYSAQWILEELDGKPYRWEDRPGDKFYILPEDEKIVREC 118

Query: 141 ---YR-KTHNQGVFDVYTPDILRCRKSGVLTGL-PDAYGRGRIIGDYRRVALYG------ 189
              +  KT    V      ++     +GV       A G G  I DY+ V   G      
Sbjct: 119 AEYWNGKTLYDYVRKNLPKEVNDAWDAGVTDETWVCAAGLGNEIVDYKMVVEKGLEDVLT 178

Query: 190 --------IDYLMKDKLAQFTSLQA-DLENGVNLEQTIRLREEIAEQH------RALGQM 234
                   ID L  D L Q   L+A  L N   L  + RL ++  E+           ++
Sbjct: 179 RIQEKKDSIDILDPDALKQLHFLEAAKLGNEAVLNYSNRLADKCEEEAGKTDDSEYKKEL 238

Query: 235 KEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKA 294
            E+A    Y    PA   QEA+Q  +   LA     NG A+S GR   ++    ++D++ 
Sbjct: 239 MELAEICRYVPFHPARTFQEAVQSIFMVLLAVHMESNGHAISLGRFDQYVYPLYKKDIEE 298

Query: 295 GKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNS 354
           G+IT+++A E+++   +K   +  LR+    E F G  ++   +I G  ++G+      S
Sbjct: 299 GRITKEKALEIIECFFIKCNELNKLRSWPDTEFFMGYQMFINLAICGQTVEGKDATNDIS 358

Query: 355 FRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFA--AKVSIDTSSLQYEND--------D 404
              +     +     P++++   +         A  A +        + ND        +
Sbjct: 359 RMCIQACREL-KLITPSVSVKCFDGTTDEVLMDALEATIEHKGGMPAFYNDKAFIKILRE 417

Query: 405 LMRPDFNNDDYAIACCVSPMIVGK-QMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKS 463
           +   + +  D+    C+   I GK      G   ++ K +   +N G D           
Sbjct: 418 MGVAEEDLVDWCPDGCIEASIPGKWDFAAKGPWLSIEKVLEITLNNGKDPATGTVFRKPD 477

Query: 464 EPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTM 523
           + I     + +++ E     + +         +I   +H +Y   A   +L    + R +
Sbjct: 478 KDIVAS-SSMEDIFEEYKKTLKYFLDLNCLTEHINDEVHVRYDLNAFRSSLVQDCIGRCL 536

Query: 524 ------------ACGIAGLSVAADSLSAIKYA--KVKPIRDEDGL---AIDFE------- 559
                           AG   A D+L+ I+Y     K +  E  L   A +FE       
Sbjct: 537 DLVEGGALYSADGGPTAGTISAGDALTGIEYLVFDKKILTMEQLLHACATNFEDESTTPT 596

Query: 560 -------IEGEYPQFGNNDPRVDDLAVDLVERFMKKI-QKLHTYRDA------IPTQSVL 605
                  ++ + P+FGN+D   D   V + E     +     + +            S  
Sbjct: 597 GKEIQMIMKNKVPKFGNDDDYADKWVVAIEEYVGHSLNHDYKSSKYGKGPVPCCFAYSQT 656

Query: 606 TITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGIS 665
            +T N+ +G + G TPDGR AG P   G +P +G ++ GA A+  SVAK+P  Y + G  
Sbjct: 657 PVTGNISFGSRIGATPDGRSAGEPVNNGVSPANGSERNGATAACNSVAKIPTIYDQKGNI 716

Query: 666 YTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEK 725
           +   + P+ +   +  +K  +  +M   F  +A       +  NV++ E+L +A + PE 
Sbjct: 717 FNMRLAPSTIANQESRQK--ILDMMRALFDKDAE-----QIQFNVVDNEVLKEAQKRPED 769

Query: 726 YPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQ 758
           +P L +RVSGY+  F SL    Q DVI RT  +
Sbjct: 770 FPDLMVRVSGYSALFTSLGVACQNDVINRTEVE 802


>UniRef50_A8MJE8 Formate C-acetyltransferase n=57 Tax=Bacteria RepID=A8MJE8_ALKOO
          Length = 849

 Score =  525 bits (1353), Expect = e-147,   Method: Composition-based stats.
 Identities = 146/751 (19%), Positives = 284/751 (37%), Gaps = 92/751 (12%)

Query: 87  AGYINKQLEKIVGLQTEAPLKRALIPFGGIK-MIEGSCKAYNRELDPMI----------K 135
           A  + ++ E IVG     P   A  P    + M +      NR  DP            +
Sbjct: 114 APLLIQEDELIVGAPCGQPRAGAFSPDIAWRWMEDEIDTIGNRPQDPFYISEEDKRYMRE 173

Query: 136 KIFTEYR----------KTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRV 185
           ++F  ++          +  + GV+++     +       L G  D+     +I     +
Sbjct: 174 ELFPFWKGKSVDEYCEDQYRDAGVWEISGESFVSDCSYHALNGGGDSNPGYDVI-----L 228

Query: 186 ALYGIDYLMKDKLAQFTSLQADLENGVN-----------LEQTIRLREEI---------- 224
              G+  + K+       L  D  + +             E  +     +          
Sbjct: 229 MKKGMIDIQKEAQEHLEKLSYDNPDDIEKIYYYKAVIETTEGVMIYARRLADHAADLAAK 288

Query: 225 AEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFL 284
               +   +++ ++       +   +   EAIQ  +      V  +N   MS GR   ++
Sbjct: 289 ETNPKRKAELQRISEINRRVPANKPSTFWEAIQAVWTIESLLVVEENQTGMSIGRVDQYM 348

Query: 285 DVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGL 344
             + + D+++G++TE EA E+   +++K+  + ++ +    + F+G   +    +GG+  
Sbjct: 349 YPFYKADIESGRMTEFEAFELAGAMLIKMSEMMWVTSEGGSKFFAGYQPFVNMCVGGVTR 408

Query: 345 DGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKF-AAKVSIDTSSLQYEND 403
           +G       ++  ++ +  +    +P++      K P  + K     V           D
Sbjct: 409 EGLDATNDLTYLLMDAVRHVKIY-QPSLATRIHSKSPKKYLKKIVDVVRSGMGFPACHFD 467

Query: 404 DLMRPDF--------NNDDYAIACCVSPMIVGKQMQF-FGARANLAKTMLYAINGGVDEK 454
           D+             +  DY +  CV P   G+  Q+   A       +   +N GV   
Sbjct: 468 DVHIKMMLAKGVSIEDARDYCLMGCVEPQKSGRLYQWTSTAYTQWPIAIELVLNNGVPLW 527

Query: 455 LKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMAL 514
              QV P    I      Y++    +   + ++ K    A  I   +H   + +  +  +
Sbjct: 528 YGKQVTPNMGDI-NQYKTYEQFEAAVKEQIQYITKLSNIATVISQRVHRDLAPKPLMSIM 586

Query: 515 HDRDVIRTMACGI-------------AGLSVAADSLSAIK---YAKVKPIRDEDGLAIDF 558
           ++  +                     +GL+   DS++AIK   +   K    +   A+  
Sbjct: 587 YEGCMESGKDVSAGGAMYNFGPGVVWSGLATYVDSMAAIKKLVFDDKKYTLQQLNEALKA 646

Query: 559 EIEG---------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITS 609
           +  G         + P++GN+D  VD +A DLV    K+ +K  T   +I     L+I++
Sbjct: 647 DFVGYDQVKSDCLKAPKYGNDDDYVDLIAADLVNFTEKEHRKYRTL-HSIMCHGTLSISN 705

Query: 610 NVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFS 669
           N  +G+ TG T +GR A  P   G +P  G D KG  A + SV+K+       G+ + F 
Sbjct: 706 NTPFGQLTGATANGRGAWTPLSDGISPTQGADFKGPTAIIKSVSKMACDNMNLGMVHNFK 765

Query: 670 IVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQL 729
           ++   L   +      +  L+       A+  G   +  N ++   LL+A ++PEKY  L
Sbjct: 766 LIAGLLDTPEGEE--GIITLLRT-----ANNIGIGEMQFNYLDNNTLLEAQKHPEKYRDL 818

Query: 730 TIRVSGYAVRFNSLTKEQQQDVITRTFTQSM 760
            +RV+GY+  F  L K+ Q ++I+RT     
Sbjct: 819 IVRVAGYSAFFVELCKDVQDEIISRTMLTHF 849


>UniRef50_B8FFL2 Formate C-acetyltransferase n=1 Tax=Desulfatibacillum alkenivorans
           AK-01 RepID=B8FFL2_DESAA
          Length = 803

 Score =  524 bits (1351), Expect = e-147,   Method: Composition-based stats.
 Identities = 163/779 (20%), Positives = 291/779 (37%), Gaps = 96/779 (12%)

Query: 43  FLAGATEATTTLWDKVMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQT 102
           +       +  ++ ++ E +    +             +I  H         E IVG  T
Sbjct: 51  YFKDKANQSKHVYVQMAEALAHSQKNR-----------SIAVHPG-------ELIVGNYT 92

Query: 103 EAPLKRALIPF-GGIKMIEGSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRCR 161
              +   L P   G+ +++   K  NRE +P+      + R      +   +   +L  +
Sbjct: 93  SRRVGGLLFPELHGLVVMQDLFKFPNRETNPLEVSRLDQARLL---SIAPFWATRMLAVK 149

Query: 162 K---------------SGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQA 206
                            G    + +A G   I  DY  +   G D +             
Sbjct: 150 TCDSWLDTFSLVLNQLMGNYYIINEAAGISHIAPDYETLCRLGTDGIAAKAAKLQKQSLM 209

Query: 207 DLEN--------------GVNLEQTIRLREEIAEQHRA---LGQMKEMAAKYGYDISGPA 249
           D +                   E+  +L  E+AE+        ++K +A          A
Sbjct: 210 DADKWYFYESVRIAAEGLAAFGERYAQLAGEMAERELDEDLAAELKGIAEVCSRVPRKGA 269

Query: 250 TNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHL 309
              +EA+Q  +F  +A        ++  GR   +L  Y E+DLKAG +T +EA+E+    
Sbjct: 270 KTFREALQSCFFAQIAINNESLDNSVCPGRMDHYLYPYYEKDLKAGLLTREEAKELAGAF 329

Query: 310 VMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPE 369
            +K+  +  + +        G       ++GG   +G+    + +  FL  +  +    +
Sbjct: 330 SVKMSEIVPVFSKYITRTHGGFFNGQIVNVGGTHKNGKDSTNELTMIFLEVMDELRMR-Q 388

Query: 370 PNMTILWSEKLPLNFKKFAAKV-SIDTSSLQYENDDLMRPDF--------NNDDYAIACC 420
           PN T    +  P  +      + S   +S    ND+++ P          +  +Y    C
Sbjct: 389 PNYTARVHKNSPKEYLDKVYGILSKGANSPSIYNDEVIVPVLKQNGVKIGDARNYTPVGC 448

Query: 421 VSPMIVGKQMQFF-GARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMER 479
           V P+  G        A  N A  +  A+N G       Q+G K++P+   +   ++V E 
Sbjct: 449 VEPVAQGVSFSSTDAALFNTAIILELALNQGRRLGRVAQIGAKTKPV-SQMTCIEDVQEA 507

Query: 480 MDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRT------------MACGI 527
            +  M     + +  L  I   + +Y        L D  +                    
Sbjct: 508 FEIQMFHGINRLLKDLQAIEIANAEYHPTPLSSMLLDGCLENGACSTRGGARYNFSGIQC 567

Query: 528 AGLSVAADSLSAIKYA---KVKPIRDEDGLAIDFEIEG--------EYPQFGNNDPRVDD 576
            GL  A DSL+AIK A     K   +E    +   +            P+FGN+DP  D 
Sbjct: 568 VGLVDAGDSLAAIKQAVFEDKKLSMEELVEHLKNNLSDDRWRHYLLNMPKFGNDDPFADV 627

Query: 577 LAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANP 636
                ++ F   +    + R    T  V ++T +  +G      P+GRR G     G +P
Sbjct: 628 WTAYALDVFKAALDGKTSTRGGKYTVGVYSVTLHEYWGTVVSALPNGRRNGESLSNGMSP 687

Query: 637 MHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHH 696
            +G+D+KG  A L S+ ++ ++   +GI++      N +G       T +  +   YF  
Sbjct: 688 SNGQDRKGPTAVLNSMNRIDYSKTDNGINFNIKFDANTVGSPAGC--TAMKSIFSTYFK- 744

Query: 697 EASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRT 755
                GG    +NV++ ++L++A +NPE YP L +RVSGY+  FN LT   ++++I RT
Sbjct: 745 ----RGGMQAQINVLDPKVLIEARDNPEAYPHLLVRVSGYSAYFNDLTPAMKEEMIRRT 799


>UniRef50_A8ZW07 Formate C-acetyltransferase n=2 Tax=Proteobacteria
           RepID=A8ZW07_DESOH
          Length = 782

 Score =  522 bits (1344), Expect = e-146,   Method: Composition-based stats.
 Identities = 153/780 (19%), Positives = 283/780 (36%), Gaps = 77/780 (9%)

Query: 44  LAGATEATTTLWDKVMEGVKLENRTHAPVDFD-TAVASTITSHDAGYINKQLEKIVGLQT 102
           + G       LW       K       PV        S +  + + YI    E + G  T
Sbjct: 16  VPGVCPERALLW---TAYFKNRANRQKPVAVQIAGAVSHVLKNKSIYIYPD-EILAGNYT 71

Query: 103 EAPLKRALIPFG-GIKMIEGSCKAYNRELDPMIK------KIFTEYRKTHNQGVFDVYTP 155
              +   + P   GI ++    K + R L+P+        K+F       N+ +     P
Sbjct: 72  SRRVGGIIYPESHGISVLMEIFKFHKRRLNPLETTPAHRWKLFATIPFWLNRNIIRKAFP 131

Query: 156 DILRCR--KSGVLTGLPDAY----GRGRIIGDYRRVALYGIDYLMKD----KLAQFTSLQ 205
            I +      G LT          G   +  ++ ++   G++  +K+    + A     Q
Sbjct: 132 TIRQQLTFAVGQLTAREYQIYETGGISHLTPNHEKILAIGLEGFLKEIEAHEQAATAPEQ 191

Query: 206 ADLENGVNL---------EQTIRLREEIAEQHRAL---GQMKEMAAKYGYDISGPATNAQ 253
            D      +         E+   L  ++A+          ++ +A          A    
Sbjct: 192 RDFYQAARIAAGGLIAFAERYADLARKMAKNEADPVRKADLERIADACKRVPRHGANTFF 251

Query: 254 EAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKL 313
           EA+Q     +++  +   G ++  GR    L  Y ++DL  G++T  +A+E++    +KL
Sbjct: 252 EAVQAMLLTHISLFQESLGESLCVGRMDQILWPYYQKDLSEGRLTRDQAKEILGAFCVKL 311

Query: 314 RMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMT 373
                       +   G   +   + GGM  +G     + S+  L  +  +    +PN  
Sbjct: 312 SETVPAYPEILAKTLGGLTSYQVVTTGGMDKNGEDATNELSYILLELMDELRMR-QPNSH 370

Query: 374 ILWSEKLPLNFKKFAAKVSIDTSS-LQYENDDLMRPDF--------NNDDYAIACCVSPM 424
           +   +  P  F     +V+    S     ND+ +            +  +Y    CV P 
Sbjct: 371 VRIHKNTPKAFYDKVVEVTTGKGSAPALYNDETIIATMQKAGYTLADARNYVAIGCVEPT 430

Query: 425 IVGKQMQFF-GARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHF 483
             GK +     A  N+   +  A+N G     + + G K+  +   +    +V +     
Sbjct: 431 SQGKTLGSTDAAIINMPLALELALNEGRRFGARRRTGAKTMAVL-QMRTMADVTDAYRTQ 489

Query: 484 MDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTM------------ACGIAGLS 531
           +     +    L  I   H  +        L D  + +                   G+S
Sbjct: 490 LRHQLGRLKNDLQAIEKAHAAFHPTPLTSMLIDGCLEKGKCSTSGGAVYNFSGIQGVGVS 549

Query: 532 VAADSLSAIKYAKVKPIRDEDGLAIDFEIEG-----------EYPQFGNNDPRVDDLAVD 580
              DSL A++    +         +D    G              +FGN+    D     
Sbjct: 550 TVGDSLYAVEKMVFEDRAMGLAELVDHLKSGLSNEAVRTRLRRLEKFGNDHAEADRWTRF 609

Query: 581 LVERFMKKIQKL-HTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHG 639
           +++ +   + ++  T R       + + T+++ +    G  P+GRR G PF  G  P +G
Sbjct: 610 VMDDYADAMAEMGQTTRGGRYNAGLYSNTTHIHFANFVGALPNGRRQGEPFASGIAPENG 669

Query: 640 RDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEAS 699
            D++G  A + S+ +L F    +GI++      NAL   D+  K  L  +   YF     
Sbjct: 670 MDRRGPTALVNSMNRLDFTRMANGINFNIKF--NALNMKDDAGKNALGSIFRVYFD---- 723

Query: 700 IEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQS 759
             GG  +  N+++ EML+ A +NP  +P L +RVSGY+  FN L+ E + ++I R+F  +
Sbjct: 724 -RGGMQVQANMLDPEMLMAARDNPSLHPHLLVRVSGYSAYFNDLSPEMKDEIIARSFVAA 782


>UniRef50_Q312S2 Formate C-acetyltransferase n=9 Tax=Bacteria RepID=Q312S2_DESDG
          Length = 829

 Score =  521 bits (1342), Expect = e-146,   Method: Composition-based stats.
 Identities = 132/646 (20%), Positives = 244/646 (37%), Gaps = 74/646 (11%)

Query: 179 IGDYRRVALYGIDYLMKDKLAQFTSLQA-----DLENGVNLEQTIRLREEI--------- 224
           + DY +V   G   L ++   +   L       ++E    LE  + + + I         
Sbjct: 194 VHDYEKVLKRGFRGLKEEAQEKIAGLDPLSPRDNVEKRPFLEAIVIVCDAIILWANRHAK 253

Query: 225 --------AEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYL-AAVKSQNGAAM 275
                           +++ MA    +    PA N  EA+Q  +F  + + ++ + G  +
Sbjct: 254 LAADMAAAETNPVRKAELETMAEICAWVPENPARNFYEAVQAQWFTQMFSRLEQKTGTIV 313

Query: 276 SFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRM-VRFLRTPEYDELFSGDPIW 334
           S GR   +   +  +D++ G+ITE+ A E+++ + + +   V    +P       G   W
Sbjct: 314 SNGRMDQYFWPFYRKDIEEGRITEESALELLECMWVGMAQYVDLYISPAGGAFNEGYAHW 373

Query: 335 ATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFK-KFAAKVSI 393
              +IGG    G       ++ FL +     P   P++      + P  +    A  +  
Sbjct: 374 EAVTIGGQTPQGLDATNDLTYLFLKSKREF-PLHYPDLAARIHSRSPERYLHDVAETIKF 432

Query: 394 DTSSLQYENDDLMRPDF--------NNDDYAIACCVSPMIVGKQMQFFG-ARANLAKTML 444
            +   +  ND+ + P +           DYA++ C    +  +     G A  N A  + 
Sbjct: 433 GSGFPKLINDEEIVPLYVSKGASFEEALDYAVSGCTEARMPNRDTYTSGGAYINFAAALE 492

Query: 445 YAINGGVDEKLKM-QVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHD 503
             +  G   K    ++G ++         ++E         +   +      +II+ +  
Sbjct: 493 MVLYNGRMLKYGENELGLETGDPTR-FETWEEFWNAYVLQHEHFLRAAFIQQHIINNVRA 551

Query: 504 KYSYEASLMALHDRDVIRTMACGI--------------AGLSVAADSLSAIK---YAKVK 546
           ++  +    ALHD  +   +                   G     DSL+AIK   +   K
Sbjct: 552 RHFAQPMGSALHDLCMKHCLDLHTPQIPEGINLGYFEYMGFGTVVDSLAAIKKLVFEDKK 611

Query: 547 PIRDEDGLAIDFEIEGE---------YPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRD 597
               E   A+    EG+          P +GNND   D +A ++ +    K  + ++   
Sbjct: 612 LTMQEVIEALKCNFEGKEDVQQMLKSAPCYGNNDEYADSIAREI-DAISVKYGRRYSPEL 670

Query: 598 AIPT-QSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLP 656
            +      +  TS+V +GK    TP+GR A  P   G++  HG D  G  A L S     
Sbjct: 671 GMHNDVRYVPFTSHVPFGKVVSATPNGRLAWTPLSDGSSASHGADVNGPTAVLQSNFSSK 730

Query: 657 FAYAKDGIS--YTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNRE 714
               +D  +        P  +  D+   K  L   +  +   +       H+  NV+NR+
Sbjct: 731 NYGYRDRAARMLNIKFTPKCVEGDEGTEK--LVSFIRTFCDLKL-----WHVQFNVINRD 783

Query: 715 MLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQSM 760
            L+ A ++PEKY  L +R++GY+  F  L+ + Q D+I RT   +M
Sbjct: 784 TLIAAQKDPEKYRSLIVRIAGYSAYFVDLSPDLQNDLIARTQHDAM 829


>UniRef50_B8J0R1 Formate C-acetyltransferase n=9 Tax=Proteobacteria
           RepID=B8J0R1_DESDA
          Length = 831

 Score =  513 bits (1321), Expect = e-143,   Method: Composition-based stats.
 Identities = 152/744 (20%), Positives = 275/744 (36%), Gaps = 95/744 (12%)

Query: 90  INKQLEKIV--GLQTEAPLKRALIPFGGIKMIEGSC-----KAYNRELDPMIKKIFTEYR 142
           ++     I    L T       + P    +++E        K Y+  L+     +  E  
Sbjct: 110 LDGDFLDIAVRDLPTRKTSPATITPEDARRVVEEIAPYWKGKTYHEALN---AALPAEVH 166

Query: 143 K-THNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQF 201
           K T++        P+ L  R   ++          + + DY ++   G + + K+   + 
Sbjct: 167 KLTYDD-------PEGLISRF--IVNETSSFRSSIQWVHDYEKILKRGFNSIKKEAREKL 217

Query: 202 TSLQA-----DLENGVNLEQTIR--------------LREEIAEQHRAL---GQMKEMAA 239
            +L       D E    LE  +               L  E+AE+        ++  MA 
Sbjct: 218 AALDPLSAKDDREKRPFLEAVMIVCDAIVLWAKRHAVLAREMAEKESDPVRKAELLRMAE 277

Query: 240 KYGYDISGPATNAQEAIQWTYFGYLAAVKSQ-NGAAMSFGRTSTFLDVYIERDLKAGKIT 298
              +    PA +  EA Q  +F  + +   Q  G  +S GR   +   Y ++D +AGKIT
Sbjct: 278 NAEHVPGEPARDFWEACQSQWFTQMFSRIEQKTGTTISNGRMDQYFQPYYKQDREAGKIT 337

Query: 299 EQEAQEMVDHLVMKLRM-VRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRF 357
           E +A E+++ + + +   +    +P       G   W   ++GG   DGR      ++  
Sbjct: 338 EAQAMELLECMWVGMAEFIDMYISPTGGAFNEGYAHWEAVTVGGQTPDGRDASNDLTYLI 397

Query: 358 LNTLYTMGPSPEPNMTILWSEKLPLNF-KKFAAKVSIDTSSLQYENDDLMRPDF------ 410
           L +     P   P++      + P  +    A  +   +   +  ND+ + P +      
Sbjct: 398 LKSKREF-PLHYPDLAARIHSRAPERYLWDVAETIKYGSGFPKLINDEEIVPLYVSKGAT 456

Query: 411 --NNDDYAIACCVSPMIVGKQMQFFG-ARANLAKTMLYAINGGVDEKLKMQ-VGPKSEPI 466
                DYA++ C    +  +     G A  N A  +   +  G  +K   Q +G ++   
Sbjct: 457 FEEALDYAVSGCTEARMPNRDTYTSGGAYINFAAAVEMVLRNGRMKKYGDQKLGVETGDP 516

Query: 467 KGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTM--- 523
           +     +D+             K   T   II+ +  ++  +    A+HD  +   +   
Sbjct: 517 RS-FTTWDQFWNAYVEQHLLFLKTAFTQQYIINKLRAEHFAQPMGSAMHDLCMKHCIDLH 575

Query: 524 -----------ACGIAGLSVAADSLSAIK---YAKVKPIRDEDGLAIDFEIEG------- 562
                           GL    DSL+A+K   + + K   D+   AID + EG       
Sbjct: 576 QEQIPEGINLGYFEYMGLGTVVDSLAAVKKLVFEEKKLSMDKLIAAIDADFEGYEDVRAL 635

Query: 563 --EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYR--DAIPTQSVLTITSNVVYGKKTG 618
               P +GNND   D +  D+ +R   +    ++            +  TS+V +GK   
Sbjct: 636 LRSAPCYGNNDEYADAIGRDI-DRISVEYGNKYSMSDLGIHNDVRYVPFTSHVPFGKVVS 694

Query: 619 NTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGIS--YTFSIVPNALG 676
            TP+GR  G P   G++  HG D  G  A L S         +D  +        P  + 
Sbjct: 695 ATPNGRTDGFPLSDGSSASHGADVNGPTAVLLSNCTTKNMGLRDRAARMLNIKFTPKCVE 754

Query: 677 KDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGY 736
            +    K  L   +  +   +       H+  NV+N+  L+ A ++P+KY  L +R++GY
Sbjct: 755 GEQGTEK--LVSFIRTFCDLKL-----WHVQFNVVNKGTLVAAQKDPQKYRNLIVRIAGY 807

Query: 737 AVRFNSLTKEQQQDVITRTFTQSM 760
           +  F  L+ + Q D+I RT    M
Sbjct: 808 SAYFVDLSPDLQNDLIARTEHDVM 831


>UniRef50_Q30WU7 Formate C-acetyltransferase n=1 Tax=Desulfovibrio desulfuricans
           subsp. desulfuricans str. G20 RepID=Q30WU7_DESDG
          Length = 811

 Score =  501 bits (1290), Expect = e-140,   Method: Composition-based stats.
 Identities = 139/639 (21%), Positives = 238/639 (37%), Gaps = 70/639 (10%)

Query: 180 GDYRRVALYGIDYLMKDKLAQFTS-----------------LQADLENGVNLE-QTIRLR 221
            D  R+   G+  L+ D   Q                    L+  L  G++   +   L 
Sbjct: 182 PDLDRLVKRGVRGLIADIDEQLEKFVMITYEDYRRHEFWLGLKEMLLGGIDYAHRYRDLA 241

Query: 222 EEIAEQHRAL---GQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFG 278
            E+A +        +++EMA         PA   QEA+Q   FG L          M +G
Sbjct: 242 TELAAKETDPVRKAELEEMARVCNRVPEHPAETFQEALQSLVFGLLMVFYDTRTFGMGYG 301

Query: 279 RTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATES 338
           R    +    + D+ +GKI ++   ++ +   +K+   R           S +  +    
Sbjct: 302 RIDQIMYPQYKSDIASGKIDDEYVVQLFECFRVKIMGKRQFWPDVMTPNLSSESHFHNCV 361

Query: 339 IGGMGLD-GRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAK-VSIDTS 396
           I G+    GR    + SF FL     +  +  P +++ W  ++   F K A + V +   
Sbjct: 362 ICGVDPKTGRDATNELSFAFLEAAERV-RTTHPTISVRWHTQIDPKFMKRALETVKLGMG 420

Query: 397 SLQYENDDLMRPDF--------NNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAIN 448
              + ND+                 +YA+  C    + GK    +    +  + +   + 
Sbjct: 421 FPAFFNDEPSIQYLLARGYTMEEARNYALGGCTLHTVPGKTSSIWPLVTSYGRILELTMY 480

Query: 449 GGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYE 508
            G D     Q+GPK+      + +Y+E +      +++ A     +       H     +
Sbjct: 481 NGWDFISNSQLGPKTGDFT-QMTSYEEFVAAYKAMIEYWANVSTKSGRAAKLQHGDTFPD 539

Query: 509 ASLMALHDRDVIRTMACGIAGLSVAADSLSAIKYAKVKPIRDE----------------- 551
             + A  D  + R   C + G +  ADS   I    V+ + +E                 
Sbjct: 540 IMMSAFTDDCIGRGKVCSLGG-AEHADSCMYIVPVAVQDVANELYVLKHGVFGENPICTP 598

Query: 552 ----DGLAIDFEIEGE-------YPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIP 600
               D +  ++E   E        P+FGN+ P VD L  D+     +             
Sbjct: 599 QEMLDAMRANWEGHEELRAKCMAMPKFGNDIPEVDQLLTDVYNWIKEIWHAQPATDGGRY 658

Query: 601 TQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGA-NPMHGRDQKGAVASLTSVAKLPFAY 659
             S  +I  +   G KTG  P GR+AG  F  GA +P+ G D  G  A + S   +    
Sbjct: 659 EVSPHSIGFHGGTGAKTGALPCGRKAGTSFSDGAVSPVQGTDVNGPSAVIKSAGSIDQHD 718

Query: 660 AKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDA 719
              G+ +     P+ +  +      NLA L+  YF    S   G+H+  NV+NR+ L+ A
Sbjct: 719 LY-GVLFNMRFSPSNIRGEKGT--ANLASLIKTYF----SDYKGKHIQFNVLNRDDLIAA 771

Query: 720 MENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQ 758
            + PEKY  L +RV+GY+  +  L    Q ++I RT  +
Sbjct: 772 KKEPEKYKDLMVRVAGYSAYWTDLPANIQDELIARTEHE 810


>UniRef50_A6CWD5 Formate acetyltransferase 2 n=4 Tax=Bacteria RepID=A6CWD5_9VIBR
          Length = 843

 Score =  498 bits (1283), Expect = e-139,   Method: Composition-based stats.
 Identities = 153/747 (20%), Positives = 278/747 (37%), Gaps = 93/747 (12%)

Query: 93  QLEKIVGLQTEAPLKRA-LIPFGGIK-MIEGSCKAY--NRELDPMIKKIFTEYRKTHNQG 148
             E I+G +  AP K + + P   +  +I+    +    R  D    +   +  +     
Sbjct: 104 DDELILG-EIAAPAKASPIYPEFSVDWIIDEILHSPFEERSNDQFYIRNEQDKNEILELC 162

Query: 149 VF-------DVYTPDILRCRKSGVLTGLP-------DAYGRGRIIGDYRRVALYGIDYL- 193
            +       ++ T  +   +K G   G            G G    D+ ++   G D + 
Sbjct: 163 AYWKGKTANEIITAHLDDDQKKGSHMGEKIFQTNNYHFAGIGHFAMDFTKLMTLGYDGVI 222

Query: 194 ----------------MKDKLAQFTSLQADLEN-GVNLEQTIRLREEIAEQHRALGQMKE 236
                             DK   + +    LE     + +  +L  E+AE      + +E
Sbjct: 223 LQANSALKDLSKQDPDYSDKRDYYKATIVCLEAAKHYIARYAQLTSEMAEHETDAKRKQE 282

Query: 237 ---MAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLK 293
              M+        G   +  +AIQ   F         NG ++S+GR   +L  + ++D+ 
Sbjct: 283 LHTMSLNCQQIAGGAPKSFWQAIQLFNFAVTLTQIEGNGHSISYGRMDQWLLPFYQKDVN 342

Query: 294 AGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWA-TESIGGMGLDGRTLVTK 352
              +++    E+++ L +K+     L+     ++ +G      + ++GG+  +G+     
Sbjct: 343 ERAVSKSFILELIEVLYVKMNNPTKLKDKGTVKVRNGRGFGGESLTLGGVDSEGKDATND 402

Query: 353 NSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAK-VSIDTSSLQYENDDLMRPDF- 410
            +   L           P + +   EK P   K    + +       +  ND        
Sbjct: 403 LTMLMLEASAH-TRMMNPWVCVRMHEKTPYELKIKTIECIRAGYGHPKLFNDTPAIKAML 461

Query: 411 -------NNDDYAIACCVSPMIVGKQMQFFGA-RANLAKTMLYAINGGV---DEKLKMQV 459
                     +YA+  CV P I GK+  +  A   N AK M   INGG          Q+
Sbjct: 462 GKGVSLAEARNYAVVGCVEPTIPGKEHGWLDAGYVNTAKMMEMVINGGRILSGPNAGQQL 521

Query: 460 GPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDV 519
           GP +  ++     +++V+E +D    +   Q  + LN+   +H        + A  +  +
Sbjct: 522 GPDTGSLET-YTTFEQVLESVDKQFAYWCDQLCSCLNVTDKIHRMIKPTPYISAFFEGCI 580

Query: 520 I--RTMACGI----------AGLSVAADSLSAIK---YAKVKPIRDEDGLAIDFEIEG-- 562
              R M  G           AG++  ADSLS IK   +   K    +   A+     G  
Sbjct: 581 ETGRDMTFGGVKYNGTAPQAAGVATCADSLSTIKKLVFDDKKYTGKQLLDAVKNNWVGYE 640

Query: 563 ---------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVY 613
                    + P +GN++   D+L   + E + + I+     R    +  V T+ +NV  
Sbjct: 641 KLYALVNSSKIPHYGNDNDEADELFTFMFECYCRHIKGRINPRGGKFSPGVYTVNANVGM 700

Query: 614 GKKTGNTPDGRRAGAPFGPGANPMH----GRDQKGAVASLTSVAKLPFAYAKDGISYTFS 669
           G  T  + DGR+   P      P+H      D +G  A + SV K+  + A +G      
Sbjct: 701 GLYTNASLDGRKNEEPISDNMGPVHTAGGSHDTQGPTAIVNSVTKVDHSLATNGTLLNLR 760

Query: 670 IVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQL 729
              +A+   +   +  L   +D Y   +     G H+  N+M+ + +  A +NPE Y  +
Sbjct: 761 FPEDAVSGIEG--RDILVSFIDEYISKQ-----GMHVQFNIMSSDKMRAAQKNPELYRDM 813

Query: 730 TIRVSGYAVRFNSLTKEQQQDVITRTF 756
            +RV+GY+  F  L K  Q D+I RT 
Sbjct: 814 LVRVAGYSAYFVELGKPLQDDLIQRTE 840


>UniRef50_UPI00016BFDA6 pyruvate formate-lyase n=1 Tax=Epulopiscium sp. 'N.t. morphotype B'
           RepID=UPI00016BFDA6
          Length = 766

 Score =  494 bits (1271), Expect = e-138,   Method: Composition-based stats.
 Identities = 158/719 (21%), Positives = 274/719 (38%), Gaps = 111/719 (15%)

Query: 119 IEGSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGR-GR 177
           +E   K Y+R  D  ++  F        + V   YT   L+CR        P  +   G 
Sbjct: 79  VEEILKVYHRWWDMSVEDRF--------KKVAFYYTNGWLKCR--------PYWFASFGH 122

Query: 178 IIGDYRRVALYGIDYLMKDKLAQFTS----LQADLENGV--NLEQTIRLREEIAEQHRAL 231
           +  DY  +   G D ++K    + T      Q +  NG+  +++      E  A    A 
Sbjct: 123 LGIDYEDLVFNGYDSIIKRAQTRLTKSCNEKQQEFLNGIIISIQALSNFYERYATAAVAA 182

Query: 232 GQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERD 291
           G++ ++A         PA   ++A+Q  +   L   K      ++F R   +L    ++D
Sbjct: 183 GKI-DLADDLKTIAHQPAKTFKQALQHIWLNTLVLQKVSGCGVLNFSRLDKYLQPLYDQD 241

Query: 292 LKAGKITEQEAQEMVDHLVMKLRMV---------RFLRTPEYDELFSGDPIWATESIGGM 342
           +KAG +T +EA  +V+    +   +             T +  EL   DP +   ++GG+
Sbjct: 242 IKAGILTREEALNLVEEFYFRNNEMMAQTDHMSEETTGTKDTLELAFDDPNY--LTLGGI 299

Query: 343 GLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSSLQYEN 402
             DG + V + S+  L     M     P + + + E +  +F K  AK   + +++   N
Sbjct: 300 NADGTSAVCELSYIMLEAANEM-RLRNPFIVVRYHEGIAEDFWKLCAKAMRNNATVVVYN 358

Query: 403 DDLMRPDFNN--------DDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGG---- 450
           D+ M P             DY    C  P I   +        N+AK +  A++ G    
Sbjct: 359 DETMIPALKYHNISAPEVYDYGFWGCNDPNIAAYEGGLRQLWMNMAKPLELALHQGDYPL 418

Query: 451 ----------------VDEKLKMQVGP----KSEPIKGDVLNYDEVMERMDHFMDWLAKQ 490
                            D  + + +GP    K++P   ++ + +E ++  +   D L  +
Sbjct: 419 EPKKEEDVAKECAWSIEDRMMGIMIGPYYGIKTKP-ANEINSMEEFLKIFEIQFDHLISE 477

Query: 491 YITALNI--------------IHYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVAADS 536
           +                    I     K + E ++           +     GL+   ++
Sbjct: 478 FRKGFEADFIIEQHETVGKMRIEDCFLKGTIENAVTWTEGGTKYHKIVAQGCGLATVINA 537

Query: 537 LSAIKYAKVKP---IRDEDG--LAIDFE--------IEGEYPQFGNNDPRVDDLAVDLVE 583
           L  I+           +E    +  ++E         + +YP+FGN+   VD  A  + +
Sbjct: 538 LYIIEKVVFDEKLLTLEELATMMRNNYEGNEHWRLKFKNKYPKFGNDIDEVDKYAQIITD 597

Query: 584 RFMKKIQKLHTYRDAIPTQSVLTITSN----VVYGKKTGNTPDGRRAGAPFGPGANPMHG 639
            FM+ I K                 S      + G+  G TPDGR A  P     +P  G
Sbjct: 598 IFMRIIAKH---NGPEYLYQFWPTYSTDRAFTIMGEHVGATPDGRLAREPISENQSPADG 654

Query: 640 RDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEAS 699
            D +G  A L S++K+PF     G      + P     D  +    +A L+  Y      
Sbjct: 655 SDLEGVTAMLNSLSKVPFNRITGG-PLNLRLHPTVAAGDKGI--DTVAALLKTYMQ---- 707

Query: 700 IEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQ 758
            +GG  L +NV++ E L  A ENP+KY  L +RV+GY+  F  + K+ Q ++I RT  Q
Sbjct: 708 -KGGMQLQLNVIDAETLKLAQENPDKYRSLCVRVTGYSAFFVEMGKKAQDELIHRTQHQ 765


>UniRef50_B8FDB2 Formate C-acetyltransferase n=1 Tax=Desulfatibacillum alkenivorans
           AK-01 RepID=B8FDB2_DESAA
          Length = 823

 Score =  494 bits (1271), Expect = e-138,   Method: Composition-based stats.
 Identities = 152/742 (20%), Positives = 270/742 (36%), Gaps = 93/742 (12%)

Query: 95  EKIVGLQTEAPLKRALIPFGG-IKMIEGSCKAYNRELD-----PMIKKIFTEYRKTH--- 145
           E I+G  +   +     P GG + ++E      NR++          ++     K+    
Sbjct: 93  ELIIGNMSSKRIGANFYPEGGSLNILEDLLHLENRQIPFKLAPMEKAELLRLGLKSIPVS 152

Query: 146 -------NQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGI-------- 190
                    G F  +       R       + +  G     G+Y  V  +G+        
Sbjct: 153 IGGKALLKPGRFSHFLDFFRAKRY-----FVTEEAGISHQAGNYGEVVSHGLVKADLYAR 207

Query: 191 DYLMKDKLAQFTSLQADLENGVNLEQTIRL-REEIAEQH---------------RALGQM 234
           D L  D L   T L AD        +TI L    +A                      ++
Sbjct: 208 DRLKADALEDGTRLNADQRAFYKSVRTIILGIRNMASNLAAEAEKKAAAQGVALERRKEL 267

Query: 235 KEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKA 294
            E A    +    PA   +E +Q  +  ++A         +SFGR    L    + DLK 
Sbjct: 268 LEAAEACLHAPYYPARTFKEGLQACWLVHMAMNLEDFEQGLSFGRLDRILLPLYKADLKK 327

Query: 295 GKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNS 354
           G +T ++A E++    +K      + +   D+ FSG+ +    ++GG+   GR    + S
Sbjct: 328 GLLTYEKAVEIMASFQLKTCETIPIYSERIDQYFSGNGVAQGITVGGVNGGGRDCTNELS 387

Query: 355 FRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKV-SIDTSSLQYENDDLMRPDFNN- 412
              L+    +  + EP + +   +K P  F + AA V ++      +  D  +     N 
Sbjct: 388 GLVLDAFSQI-KTREPALHVRVHKKTPPWFLEKAAAVAALGCGKPSFFGDKAVIKALENT 446

Query: 413 -------DDYAIACCVSPMIVGKQMQFF-GARANLAKTMLYAINGGVDEKLKM----QVG 460
                   DYA+  CV     G+       A  NL   +  A+N G     +     + G
Sbjct: 447 GMSKPHARDYAVIGCVEMASQGRTYNSSDAALFNLPLCLELALNQGYRFGSRRIPALRFG 506

Query: 461 PKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVI 520
             +  ++ ++  +D+V+      +     + +  + +I   +  +        +    + 
Sbjct: 507 APTPSVE-EMDAFDQVLRAFKTQVRDSVNEMVKVITMIEQAYRVHRTTPVNSIITQGCLE 565

Query: 521 RTM------------ACGIAGLSVAADSLSAIKYAKVKPIRD-------------EDGLA 555
                          +   AGL+ A DSL A+K       R              E    
Sbjct: 566 CGKDVTWGGAMYDLTSVQAAGLADAGDSLYALKRVVFDEKRMSLKAFVDILKSNWEGQEK 625

Query: 556 IDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGK 615
           +  EI  ++P++GN D   D +     + +   +      R       + ++T +  +GK
Sbjct: 626 LRQEISQKFPRYGNGDKDADRMTQVAADAYTDAVTAHKNSRGGQYIAGIYSMTCHHGFGK 685

Query: 616 KTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNAL 675
            TG  P+GR AG     G +P+ G D+KG  A L S A L  +   +  +       N  
Sbjct: 686 ATGALPNGRPAGYRLSNGLSPVDGVDKKGPTAVLQSAASLDSSQWGNCCALNIKFDGNQF 745

Query: 676 GKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSG 735
                 +   L+GL+  Y +      GG  +  N+++ E L +A E+P  +P + +RV+G
Sbjct: 746 KGTKGAK--ILSGLITAYMNM-----GGMQIQPNILDAETLREAKEDPSAHPGIVVRVAG 798

Query: 736 YAVRFNSLTKEQQQDVITRTFT 757
           Y   FN L    Q +VI+RT  
Sbjct: 799 YCAYFNDLQPMVQDEVISRTSH 820


>UniRef50_A6G8C6 Pyruvate formate-lyase 2 (PflD) n=1 Tax=Plesiocystis pacifica SIR-1
           RepID=A6G8C6_9DELT
          Length = 889

 Score =  470 bits (1209), Expect = e-130,   Method: Composition-based stats.
 Identities = 149/770 (19%), Positives = 272/770 (35%), Gaps = 132/770 (17%)

Query: 95  EKIVGLQTEAPLKRALIPF-GGIKMIEGSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVY 153
           E I+G  T   +  A+ P  GG+ M+    +   REL+P+      E  +     +   +
Sbjct: 120 ELIMGNPTAHRIGSAIHPEYGGMLMLPELDQLTRRELNPLAAT--DEQLRRLEDDILPWW 177

Query: 154 TPDILRCRKSGVL--------------TGLPDAYGRGRIIGDYRRVALYGIDYLMKD--K 197
               +  R   +                 L    G   ++ DY  V   G+  ++++   
Sbjct: 178 FTCSILSRAPLLAADKLLQNRLVEARDFVLTQFAGIAHVVPDYPTVLRLGLRGVLEELRA 237

Query: 198 LAQFTSLQADLE-----------NGVNLEQTIRL---REEIAEQHRALGQMKEMAAKYGY 243
             +        E                ++  R      E+AE      +++E+AA    
Sbjct: 238 AQRHAQSSEQREFYEAATICVTAAMDFAQRQARFVAGAAEVAEDPERAAELRELAAVLAR 297

Query: 244 DISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQ 303
               PA    EA+Q  +  ++   +      +SFGR   +L  +++ DL+AG++ E  A 
Sbjct: 298 VPIEPARTYHEALQSVFTTHVVIHQESFQHGISFGRIDQYLAPFLDADLEAGRLDEARAV 357

Query: 304 EMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLD-GRTLVTKNSFRFLNTLY 362
           E+    + K      L      E FSG    +  ++GG     G    T  +   L   Y
Sbjct: 358 ELTGCFLAKAAEQLPLFNAMSTEFFSGLSSASGLTLGGTDPRTGADATTSVTRAILLA-Y 416

Query: 363 TMGPSPEPNMTILWSEKLPLNFKKFAAKVSI-DTSSLQYENDD--------LMRPDFNND 413
                 +PN+ +      P   ++ A  V            D+        L  P    +
Sbjct: 417 HQLRLRQPNLHLRVHPGTPEGLRRLAYAVLREGGGMPALFRDEGVVDAIRGLGVPHEAAE 476

Query: 414 DYAIACCVSPMIVGKQMQFFG-ARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLN 472
           DYAI  CV   +  +     G A  +L   +        D  ++    P        + +
Sbjct: 477 DYAIVGCVEWGVPYRSFPAAGAAFVSLPAIL-------RDLLMEEHEPP--------LRD 521

Query: 473 YDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTM--------- 523
            D+V       ++   ++ +   + I   H +Y     L A+      R           
Sbjct: 522 MDDVWAAFRAAVEARIEEVVAGNDAIERAHAEYRPTPMLSAVVRGCAARGKDVCAGGADF 581

Query: 524 ---ACGIAGLSVAADSLSAIKYAKVKPI-------------------------------- 548
                   G++  ADSL+ ++     P                                 
Sbjct: 582 NSTGVQAVGVADVADSLTVLEQLVFPPPGGGRPELSRGRGIGPRGRALGRDGFHHRLLER 641

Query: 549 -------------RDEDGLAIDF--------EIEGEYPQFGNNDPRVDDLAVDLVERFMK 587
                        R    LA DF         +    P++G +    +  A  + E + +
Sbjct: 642 TGTVKSSQSLSLGRLRRALARDFVDEEALRQRLRNHVPKYGQDAGPPERWARRVAELYAE 701

Query: 588 KIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVA 647
            +++    R         ++T++V +G++ G  P GR+AG P   G +P  G D +G  A
Sbjct: 702 LLREHLNPRHGPYAPGFWSMTTHVGFGRRLGALPSGRKAGRPLANGLSPSSGADNRGPTA 761

Query: 648 SLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLN 707
           SL SVA +   +  +G +   ++ P+ +    EV    +  L+ GYF       GG  + 
Sbjct: 762 SLLSVAAVSGGFVGNGYALNETLDPSFVRG--EVGLARIDQLVRGYF-----AAGGNQVQ 814

Query: 708 VNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFT 757
            NV++   L+DA  +PE++  L +R+SGY+  FN L++  + ++I R+  
Sbjct: 815 FNVLDTAELVDAKAHPERHRGLVVRISGYSAYFNDLSEAMKDELIARSRH 864


>UniRef50_B8FHW6 Formate C-acetyltransferase n=2 Tax=Desulfobacteraceae
           RepID=B8FHW6_DESAA
          Length = 1000

 Score =  468 bits (1205), Expect = e-130,   Method: Composition-based stats.
 Identities = 147/744 (19%), Positives = 276/744 (37%), Gaps = 89/744 (11%)

Query: 90  INKQLEKIVGLQTEAPLKRALIPFG-GIKMIEGSCKAYNRELDPMIKKIFTEYRKTHNQG 148
           I ++ + + G  T   +   + P   G  +        +R L+P    +  +  +  +  
Sbjct: 266 IIRKDDLLAGTSTTKEVGVIVYPDAHGTMLWGELYTVPHRSLNPY--DVSEDTVRLLHHE 323

Query: 149 VFDVYT----PDILR------------CRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDY 192
           VF  +T     + +R             R +               I D+ ++   G   
Sbjct: 324 VFPYFTHRNFKEWVRYNYQSPLCQAIDERYAVYFVW--KQAALSHTIPDFPKILSLGASG 381

Query: 193 LMKDKLAQFTSLQADLENGVNLEQTIRLREEI-----------------AEQHRALGQMK 235
           ++ +   +             LE  I   E +                     +   +++
Sbjct: 382 VINEIKGKLNQEGLSDRQKGLLEGMIHSMEGMIAYSKNLSAQAAEEAAQESDPKRKAELE 441

Query: 236 EMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKA- 294
            +A      +  PA N  EA+   +  ++        A +S GR   +L  Y E DL+  
Sbjct: 442 NIAQACAQVVENPARNLDEAVNAVWITWVGMHMENTNAGLSMGRLDQWLQPYYETDLEKI 501

Query: 295 --GKITEQE---AQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTL 349
             GK  E     A E+V  L M+      L     +  F G       ++GG+  +G+  
Sbjct: 502 SDGKEREAYIKHAIELVGCLFMRCTDHLPLTPDLANWYFGGSSSDQAITLGGVTPEGKDA 561

Query: 350 VTKNSFRFLNTLYTMGPSPEPNMTILWS-EKLPLNFKKFAAKVSIDTSS-LQYENDDLMR 407
           V   ++ FL     +G   +PN+   ++ EK    + K   +V++ T++     +D  + 
Sbjct: 562 VNDMTYIFLKVTEMLGIR-DPNVNARYNREKNSDAYLKRLCEVNLITAATPSLHSDQAVI 620

Query: 408 PDF--------NNDDYAIACCVSPMIVGKQMQFFGA-RANLAKTMLYAINGGVDEKLKMQ 458
                      + ++++   CV P + G+ +        N+   +  A+N G+   +  +
Sbjct: 621 ESLKEFDYAQEDLNNWSATGCVEPTLSGRHIGHTNFQMMNMVAALEMALNNGLHPLMNWR 680

Query: 459 VGPKSE-PIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDR 517
           +GP++  P +G    +D+  E       +L  Q +   N++   H        L +L D 
Sbjct: 681 LGPETGEPAQGAFKTFDDFFEAFTKQFAFLIDQSVEYNNLMGLAHQAIRPTPFLSSLIDD 740

Query: 518 DV----------IRTMACGIA--GLSVAADSLSAIKYAKVKPIR-----DEDGLAIDFE- 559
            +           R  + G A  GL+   DSL AIK              ++ +A +F+ 
Sbjct: 741 CISTAADVTHGGARYNSSGAACIGLADVTDSLMAIKKLVYDDKSVSFADLKNAVADNFQS 800

Query: 560 -------IEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVV 612
                  I  + P FG+      ++A  + +           YR    T    +++++V+
Sbjct: 801 EPALHALITHKVPLFGSGSEEAVEMANRVAKFAHDHYGTHTNYRGGKYTVGFWSMSNHVI 860

Query: 613 YGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVP 672
           YG  +G  P G+  G PF PG  P         + ++  VA+L   Y  + +++   IVP
Sbjct: 861 YGTLSGALPSGKLEGKPFTPGLTPQP-IASPNLLDNIRDVARLSPKYITNNLAFNVKIVP 919

Query: 673 NALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIR 732
                  E    N+   +  YF       GG  + +N +  + L DAM NPE Y  L +R
Sbjct: 920 GP-NDTHEQTVDNMFSYVKTYFDL-----GGMQMQLNAVTSDTLKDAMANPENYRNLLVR 973

Query: 733 VSGYAVRFNSLTKEQQQDVITRTF 756
           +SGY   F +L ++ Q ++I R  
Sbjct: 974 ISGYNAYFVTLNRDMQLELIERAQ 997


>UniRef50_D2LJ70 Formate C-acetyltransferase n=1 Tax=Rhodomicrobium vannielii ATCC
           17100 RepID=D2LJ70_RHOVA
          Length = 829

 Score =  466 bits (1200), Expect = e-129,   Method: Composition-based stats.
 Identities = 158/743 (21%), Positives = 275/743 (37%), Gaps = 87/743 (11%)

Query: 89  YINKQLEKIVGLQTEAPLKRALIPFGG----IKMIEGSCKAYNRELDPMIKKIFT--EYR 142
           YI+     +VG  T  P      P  G    ++  +    ++  E++   ++  T  E  
Sbjct: 94  YIDDN--PLVGTVTSKPAGVYPYPEWGAEWILREADQPMVSHLGEVELSDEERATLIETA 151

Query: 143 KTHNQGVFDVYTPDILRCRK--------SGVLTGLPDAYGRGRIIGDYRRVALYGIDYLM 194
           K       +    ++ R           +  L      Y  G    DY      G+  ++
Sbjct: 152 KYFQTRSAEARARELSRELHGFDPRDSVAAGLITETAPYTIGSGTLDYATFIRRGLGDII 211

Query: 195 KDKLAQFTSL--------QADLENGVNLE---------QTIRLREEIAEQHRAL---GQM 234
           ++   +  +L        + D    V +          +   L E++A +        ++
Sbjct: 212 RETEGRLKALPLTQENASKIDFYRAVLISLNALIHLAHRYADLAEKLAAETGDAVRRAEL 271

Query: 235 KEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKA 294
            E+A    +    P  N +EAIQ+ +F +L     Q+G   S GR   +LD + + D   
Sbjct: 272 LEIAEVCRHVPENPPRNFREAIQFWWFLHLGNQIEQSGCGSSPGRIGQYLDPWFQADKAQ 331

Query: 295 GKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNS 354
              T ++AQ     L +K+    + +        SG     T ++GG+   G+   T+  
Sbjct: 332 NGFTREDAQAWFKCLFVKILEYGYYQGLISARTNSG-HTGHTINLGGLNAAGQDATTELD 390

Query: 355 FRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSI-DTSSLQYENDDLMRP----- 408
              L+T   +  + +P +TIL+ + L  +F   A ++        Q+ N  L+       
Sbjct: 391 SVLLDTQIEL-QNIQPTITILYHDGLQEDFLLKAIELERTGLGQPQWMNTRLIIERTLAR 449

Query: 409 -------DFNNDDYAIACCVSPMIVGKQMQFF-GARANLAKTMLYAINGGVDEKLKMQVG 460
                    +        CV   + G+      G   NLAK +  A++ G+D      VG
Sbjct: 450 HAKNGITIEDARASINMSCVGTGVEGRTAFIHEGGTFNLAKCIELALHDGIDPGTGFFVG 509

Query: 461 PKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVI 520
            ++   +    ++++        ++ L K      ++      +    A   AL+   + 
Sbjct: 510 ARTGDARS-FKSFEDFYGAWLRQVEHLFKVQRAFGSVSTKALGETIAPAFRSALYGGCLE 568

Query: 521 RTMACGIAGL------------SVAADSLSAIKYAKV---KPIRDEDGLAIDFEIEGE-- 563
           R       G+              AA+SL+AIK+      +    E   A+D   EG   
Sbjct: 569 RGKHVFDGGVDYYLYFVISNAGVDAANSLAAIKHLVFDTGRLTLGELLDAVDANFEGHDR 628

Query: 564 -------YPQFGNNDPRVDDLAVDLVERFMKKIQ--KLHTYRDAIPTQSVLTITSNVVYG 614
                   P+ GN DP +D L   + +   K         + D I      +++ +  YG
Sbjct: 629 IRTLCLNAPKHGNGDPAIDALVRRVYDDAFKTFHAAGYSYFGDHIANIEAYSLSIHNYYG 688

Query: 615 KKTGNTPDGRRAGAPFGPG-ANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPN 673
            KTG  P GR+ G P   G  +   G D+KG +A + S A+   A       +     P 
Sbjct: 689 LKTGALPSGRQKGRPLTDGSVSATPGTDKKGPLALIQSAAQAVDAVKYGSNHFNMKFHPT 748

Query: 674 ALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRV 733
           AL      RK  L  L+  Y        GG H+  NV+  + L  A  NP+ Y  LT+RV
Sbjct: 749 ALAGIGGARK--LLSLIKTYMDA-----GGSHIQFNVVTSDTLRKAQANPDAYKGLTVRV 801

Query: 734 SGYAVRFNSLTKEQQQDVITRTF 756
           +G++  F  L K  Q ++I RT 
Sbjct: 802 AGFSAYFTRLHKGVQDEIIERTE 824


>UniRef50_A5CZF4 Pyruvate-formate lyase n=1 Tax=Pelotomaculum thermopropionicum SI
           RepID=A5CZF4_PELTS
          Length = 835

 Score =  466 bits (1199), Expect = e-129,   Method: Composition-based stats.
 Identities = 144/706 (20%), Positives = 270/706 (38%), Gaps = 81/706 (11%)

Query: 125 AYNRELDPMIKKIFTEYRKTHNQGVFDVYT-PDILRCRKSGVLTGLPDA--YGRGRIIGD 181
            +  + D + + I  E    H   +FD     +    R         +   +G G  +  
Sbjct: 138 EHMPKYDAVNEAIRAELGDDHFDLMFDHGMIYEGRAVRHHRDRGLFQNWGAFGGGNCMPT 197

Query: 182 YRRV--ALYGIDYLMKDKLAQFTSLQADLENG---------------VNLEQTIRLREEI 224
              +   L  I  L KD+L +   L A ++                 ++    I+  E  
Sbjct: 198 KPAIDNGLNYIIALAKDELNRMEKLGAFVQGAASNAFRKYNLLKAIIISCNAVIKFAERH 257

Query: 225 AEQHRA----------LGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNG-A 273
           AE  R             ++ ++A       +    N  EA+Q   F +LAA K      
Sbjct: 258 AELARKQAESCTDPVRKAELLKIAEVCQNVPANRPRNFWEAVQSLRFLHLAAWKESTERP 317

Query: 274 AMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPI 333
            +  GR    L  Y ++D+  G +T Q+A E++  L +K+R    L T + +   +   +
Sbjct: 318 EVGVGRIDQILYPYYKKDIDEGTLTRQDAAELLGALWLKIRETENLVTIKREHRAAPGTL 377

Query: 334 WATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSI 393
               ++GG    G  L+ + S+  L  +       EP + I + + +  +F   A + + 
Sbjct: 378 LPNVTLGGRNELGEDLINEVSWIVLEVMRQ-TKLSEPAIYIRYHDGIDEDFMIHALECNR 436

Query: 394 DTSS--LQYENDDLM--------RPDFNNDDYAIACCVSPMIVGKQMQFFGARANLAKTM 443
           D       + ND+L          P  +  ++  + C+   +   + Q      N AK  
Sbjct: 437 DFGGGNPAFLNDELGTQRYLARGVPLKDAVNWNASGCLGYHLDCGEHQGGFFSLNHAKIF 496

Query: 444 LYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHD 503
              +  G D +   Q+G K+  +     +  + ++     +D+  ++      I   +  
Sbjct: 497 EITLYNGFDPRTGKQLGLKTGDVT-KFTSLQQFIDAFYKQVDYFCERLRKHYFIWWCVEQ 555

Query: 504 KYSYEASLMA--LHDRDV---------------IRTMACGIAGLSVAADSLSAIKYAKVK 546
           + S  + L A  L++  +               +R+   G  G++  ADSL+AI++    
Sbjct: 556 EISPMSGLRAAMLYEDCIPAGLCSREGGARYPSLRSSWIGDRGITDIADSLAAIQHLVFD 615

Query: 547 P---IRDEDGLAIDFEIEGE---------YPQFGNNDPRVDDLAVDLVERFMKKIQKLHT 594
                  E   A+    EG+          P++GN++   D+L  +L+    + +Q    
Sbjct: 616 TKQVTMAELLDAMRNNWEGKEELRQMCLNAPKYGNDEDLPDNLFGELMFGTQRIMQSRPD 675

Query: 595 Y-RDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGAN-PMHGRDQKGAVASLTSV 652
                 P         ++  G   G  P+GR A  P    A+  M G D  G  A + S 
Sbjct: 676 PITGEKPILFKGAAAGHITQGASVGALPNGRFAYKPLNDAASSAMPGMDVNGPTAVINSA 735

Query: 653 AKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMN 712
            K  +A+   G ++        L   ++++K  L  ++  +F       GG H+  N+ +
Sbjct: 736 TKGNYAFEYVGFTHNMKFSKQTLNTPEKLKK--LINILKTFFK-----RGGWHIQFNIHS 788

Query: 713 REMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQ 758
            E LLDA ++PE+Y  L +RV GY+  F  L  E Q++++ RT  +
Sbjct: 789 VEELLDAQKHPERYRNLLVRVGGYSAYFIDLPPELQEEIVQRTMHE 834


>UniRef50_C6BT93 Formate C-acetyltransferase n=6 Tax=Desulfovibrio
           RepID=C6BT93_DESAD
          Length = 817

 Score =  463 bits (1192), Expect = e-128,   Method: Composition-based stats.
 Identities = 154/782 (19%), Positives = 289/782 (36%), Gaps = 93/782 (11%)

Query: 56  DKVMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGG 115
             + E  +              V   + +H   +++     IVG  T         P   
Sbjct: 48  KFLNEVYEKHQGEPVVY-IRAKVFERVLTHKKIFLDGN--PIVGTLTGVRAGVYAYPEWN 104

Query: 116 IKMIEGSCKAYNR----------ELDPMIKKIFTEYRK----THNQGVFDV-YTPDILRC 160
           +  I+   +              E   +++K +  ++       N  ++   Y     + 
Sbjct: 105 VSWIKEEMQMAKMASLGEMKIPAETQELLEKTYKLWKGRTCIDQNNTMYKEKYGESAKKY 164

Query: 161 RKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLENGVNLE----- 215
            K+G+          G  I DY  V   GI +L+++   + T     L N   ++     
Sbjct: 165 AKAGMYYENVSV-ASGSGIADYGLVLNKGIRHLIEEVRTRLTETPNILANRDKIDLYRSM 223

Query: 216 --------QTIRLREEIAEQ-------HRALGQMKEMAAKYGYDISGPATNAQEAIQWTY 260
                   +      ++AEQ        +   ++ E+A         PA N +EAIQ  +
Sbjct: 224 LITFDAVIKHSHRYADLAEQTAADESDPKVKAELLEIAEICRRVPEHPARNFREAIQSFW 283

Query: 261 FGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLR 320
           F +L     Q   A+S GR   ++  + ++D+  G +T ++   M+    ++   +   +
Sbjct: 284 FTHLCVATEQMACAVSPGRYGQYMYPFFKKDIDEGNLTREQVLTMLKFQWIRHLELGEYQ 343

Query: 321 TPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKL 380
              Y    SG     + +IGG+  DG    T+     L T   M  S +P +T+L+  KL
Sbjct: 344 GNSYALTLSG-HTGQSMTIGGVDKDGNDASTELEELMLETQIQM-KSIQPTLTLLYHPKL 401

Query: 381 PLNFKKFAAKVSIDTSS-LQYENDDLMR----------PDF----NNDDYAIACCVSPMI 425
             ++ +   +     S   Q  N++++           PD     +  +     CVS  +
Sbjct: 402 KESYMQKVVECIRGGSGQPQILNNNVVIQRTLARFAQYPDGITLEDARNCGNYGCVSTGV 461

Query: 426 VGKQMQFFGAR-ANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFM 484
            GK           LAK +   +N G     K  VG ++         ++++ E +   +
Sbjct: 462 CGKGSFITQEDQPCLAKVVELVLNNGKCPVTKKMVGAETGDPTT-FETFEDLYEGVKGQL 520

Query: 485 DWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGLS------------- 531
           D L +      ++      +        A++D  + + M C  AG +             
Sbjct: 521 DNLFRISRAHSDLSQMARLQVVPSVFRSAMYDGCIEKGM-CEEAGGTRYPQVNPIMTAGV 579

Query: 532 VAADSLSAIKYAKV--KPIRDED---GLAIDFEIEGEYPQFGNNDPRVDDLAVDL---VE 583
            AA+S+ AIK+     K +  E+    L  +FE   E  Q   + P+  +   D+   V+
Sbjct: 580 DAANSILAIKHLVYDTKAVTMEELIQALKANFEGYEELRQMCFDAPKHGNDYEDVQAFVQ 639

Query: 584 RFMKKIQKLHTYRD----AIPTQ-SVLTITSNVVYGKKTGNTPDGRRAGAPFGPG-ANPM 637
           RF + +  +H  +        T     +++ +  +G   G  P+GR+AG     G  + M
Sbjct: 640 RFYRDVDAIHHAQGPDCFGQRTPLDAYSLSYHNYFGGMMGALPNGRKAGVALTDGSVSAM 699

Query: 638 HGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHE 697
            G D++G  A + S A+           +     P+ L      +   L  L+  Y    
Sbjct: 700 PGTDKEGITALIKSGAEAIDTVRYGANHFNVKFSPSVLEGPQGAK--TLISLIKTYCDF- 756

Query: 698 ASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFT 757
               GG H+  N ++ + L DA +NP+ Y  L +RV+G++  F  L    Q ++I RT  
Sbjct: 757 ----GGSHIQFNCVSSDTLKDAQQNPQDYSDLIVRVAGFSAYFTRLDCGVQNEIIKRTEY 812

Query: 758 QS 759
            +
Sbjct: 813 DA 814


>UniRef50_B1BA70 HpdB protein n=1 Tax=Clostridium botulinum C str. Eklund
           RepID=B1BA70_CLOBO
          Length = 841

 Score =  454 bits (1168), Expect = e-126,   Method: Composition-based stats.
 Identities = 144/710 (20%), Positives = 264/710 (37%), Gaps = 108/710 (15%)

Query: 131 DPMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGI 190
           +  +K+   EYR   N     +Y P ++                 GR +  Y  V   G+
Sbjct: 156 EKFLKETMPEYRDLVNAFKTVLYPPSVISI-------------MEGRWVPAYDIVVEKGL 202

Query: 191 DYLM---KDKLAQFTSLQADLENGVNL--------EQTIRLREEIAEQH----------R 229
           D ++   KD +        ++   V          E  I   +  A +            
Sbjct: 203 DAVIDECKDNIKNTLPTTREVAEKVIFWKSVILVCEGVINWAKNYANEALSMASKETNDE 262

Query: 230 ALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIE 289
              ++ +MA    +  + PA    E +Q  +  ++A         +S GR    L    +
Sbjct: 263 RKKELLKMAETLNWVPAKPARTFYEGLQAAWTAHIAVSLDGPIVGLSPGRWGQLLYPLYK 322

Query: 290 RDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTL 349
           +DL+ G +  +EA E+++ + +K     ++    ++ L SG+ ++    +GG+   G   
Sbjct: 323 KDLEKGLLKREEAVELMELIRVKFSSEEYVSPRSWEALASGN-LFQHMIVGGVDSKGNCS 381

Query: 350 VTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSI-DTSSLQYENDDLMRP 408
                   L    +M  + +P + ++++ K        AA+ +   +    + N++    
Sbjct: 382 DNDLEEIILEAGTSM-QTIQPTLGVMFNSKTSNKLLMKAAECTKTGSGYPAWFNNEKCIE 440

Query: 409 DF------------NNDDYAIACCVSPMIVGKQMQ-FFGARANLAKTMLYAINGGVDEKL 455
                         +  D AI  CV   + G        A  N  K +   +N G+D + 
Sbjct: 441 HLLQNHQEENITIEDARDVAIGGCVEVQMQGNCHGICHPAFFNELKCLEIVLNDGIDPRT 500

Query: 456 KMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALH 515
            ++         G    ++++        +   K Y+   N +  +H + +       L 
Sbjct: 501 GIRC----FEPLGTFDTFEDLWAAWCKVEEKYLKVYMHYWNYVLAVHREINPLIMGSVLV 556

Query: 516 DRD-------------VIRTMACGIAGLSVAADSLSAIKYAKVKPIR-----DEDGLAID 557
                             +T+    +G+   A+SL+AIK    +  +      +  L  +
Sbjct: 557 KDCLSEGKPLDSNGARYNKTITLLNSGMVNVANSLAAIKKLVYEDKQYSINDLKIALKNN 616

Query: 558 FEIEG---------------------------EYPQFGNNDPRVDDLAVDLVERFMKKIQ 590
           F  E                              P+FGN+D  VD + VDL E +     
Sbjct: 617 FGFESADKTGNFSMLEQKCMDSTYKRLHNDLLNTPKFGNDDDYVDTIFVDLWEHYNNTCL 676

Query: 591 KLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGA-NPMHGRDQKGAVASL 649
              TY       + L+I+++  +G+    TPDGR AG     G  +   G D+ G +A L
Sbjct: 677 SETTYLGLQWIPAALSISAHGPFGRVCSATPDGRVAGVSLTDGILSATPGTDKNGPIALL 736

Query: 650 TSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVN 709
            S  KL     +  +     + PNA+   D  +K  L  L+  YF      +GG H+  N
Sbjct: 737 NSGVKLDSVKMR-SVQLNMKLHPNAIKNVDGSKK--LVNLIRTYFE-----QGGYHIQFN 788

Query: 710 VMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQS 759
           V++ ++L DA  NPEKY  L +RV+G++  +  L+K  Q ++I RT   S
Sbjct: 789 VVDSKILRDAQHNPEKYRDLIVRVAGFSAYWVELSKPIQDEIIARTEYTS 838


>UniRef50_B8FMK7 Formate C-acetyltransferase n=1 Tax=Desulfatibacillum alkenivorans
           AK-01 RepID=B8FMK7_DESAA
          Length = 838

 Score =  448 bits (1152), Expect = e-124,   Method: Composition-based stats.
 Identities = 133/679 (19%), Positives = 229/679 (33%), Gaps = 104/679 (15%)

Query: 175 RGRIIGDYRRVALYG-----------IDYLMKDKLAQFTSLQADL---------ENGVNL 214
            G ++  Y  V   G           +D L  +      + Q            +     
Sbjct: 171 SGHLVPGYEDVLKKGWKGVHDYLASRLDALGPENQNSHQANQLKAMMTAATMPRDLAARY 230

Query: 215 EQTIRLREEIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQN--G 272
              IR  E+         ++  MAA   +    P  +  EAIQ  +  ++  +  +N  G
Sbjct: 231 ASLIRDMEQKESDPERKEELARMAANLDHTPWNPPRDFWEAIQALWLTHMLVLSDENYPG 290

Query: 273 AAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMV--RFLRTPEYDELFSG 330
             +SFGR   +L  Y E  +  G +  +  +E++    +         +RT     + +G
Sbjct: 291 PGVSFGRVDQYLLPYWEASMAQG-MDREWGKEILKCFWIHANTAYDAMIRTGANGGITAG 349

Query: 331 DPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAK 390
                  ++ GMG DG  L    ++ FL  +  M P  EP   +      P         
Sbjct: 350 Y--GQLITLSGMGPDGTDLTNDLTYVFLEVIDEMSPILEPKPNVRLHANTPEELYDHIID 407

Query: 391 VSIDTSSLQY--------------ENDDLMRPDFNND----DYAIACCVSPMIVGKQM-Q 431
           +  ++    +              E +   R D  N+     YA   C+   +VG     
Sbjct: 408 MIAESQGAPFLLNFDERSMAGMMREAEKAGRQDLINESNVWQYAPVGCLENTMVGNDRSG 467

Query: 432 FFGARANLAKTMLYAINGG------VDEKLKMQV-----GPKSEPIKGDVLNYDEVMERM 480
                 NL K + +A+ GG       D  +  +      G  +     +   ++E     
Sbjct: 468 TVDINLNLLKAVEFALTGGADLLPYKDTIMGKEYPIDASGIPTGDPT-EFTVFEEFFAAF 526

Query: 481 DHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAG----------- 529
                 + K+ +        +   Y     L  L      +       G           
Sbjct: 527 AKQTRHIIKKAMDLYETSESVRAAYHPTPYLSCLVKGCAEKGKDVTQGGAELSFVTIEAV 586

Query: 530 -LSVAADSLSAIKYAKVKP---IRDEDGLAIDFEIEGE----------YPQFGNNDPRVD 575
             +   DSL A+KY           E   A+    EG            P++G +D   D
Sbjct: 587 TFATTVDSLLAVKYLVFDEKICTMAELIQALKDNWEGHDILMARAKFKAPKYGRDDDEAD 646

Query: 576 DLAVDLVERFMKKIQKLHTY-RDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGA 634
           ++A  +++ + ++  K  T          +L+    V  G     +PDGR  G       
Sbjct: 647 EMARKVMDLWTEETWKHKTQSTGRQARPGMLSWNYWVGDGYILHASPDGRPKGQFLSNAI 706

Query: 635 NPMHGRDQKGAVASLTSVAKL---------PFAYA----KDGISYTFSIVPNALGKDDEV 681
            P +G D  G  ++  SV K           F        +G S+T +  P+ L   D +
Sbjct: 707 CPTNGADINGPTSNANSVGKALGGRKPGKGDFGDYLNSLPNGASHTITFNPSILA--DPL 764

Query: 682 RKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFN 741
            K      + GY  +     GG  L +N+++ +ML DA +NP  Y  L +R++GY   F 
Sbjct: 765 HKEKFKAYLKGYVQN-----GGTALQINMLDADMLKDAQKNPADYRHLLVRITGYNAYFT 819

Query: 742 SLTKEQQQDVITRTFTQSM 760
           S+ KE Q +VI R   + +
Sbjct: 820 SIGKELQDEVIARLSHEGL 838


>UniRef50_B0MIH0 Putative uncharacterized protein n=1 Tax=Anaerostipes caccae DSM
           14662 RepID=B0MIH0_9FIRM
          Length = 803

 Score =  444 bits (1142), Expect = e-123,   Method: Composition-based stats.
 Identities = 143/638 (22%), Positives = 245/638 (38%), Gaps = 87/638 (13%)

Query: 172 AYGRGRIIGDYRRVALYGIDYLMKDKLAQF------TSLQADLENGVNLEQTIRLREEIA 225
            +    +  +Y R    G+  +  + +++          +      + ++  IR  +  A
Sbjct: 196 WFVGNHLNLNYGRALQKGLLQMKDEIISRLGSSSDPEKSEYYEAARIAVDAVIRFIKRYA 255

Query: 226 EQH-----------RALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAA 274
           ++                ++K MA         PA +  EA+Q T+  ++ A   Q G+A
Sbjct: 256 DELDLHSQNTNVTEERSRELKRMADICRKISEKPAKSFYEAVQLTWMLHIIANI-QGGSA 314

Query: 275 MSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIW 334
           +SFGR   +L  Y ++D + G+IT  EA+E+V  L +K+   +                 
Sbjct: 315 LSFGRLDQYLYPYFKKDTEEGRITYSEAKELVGCLWLKVNEPKMR-------------TV 361

Query: 335 ATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAK-VSI 393
            + ++GG+  DG+    + +   L T    G  P PN+ +  +   P    + A + +  
Sbjct: 362 QSVTLGGITPDGKDAANELTRICLQTAKDAG-MPYPNVGLRVNRLNPDWIYEEALETIKA 420

Query: 394 DTSSLQYENDDL--------MRPDFNNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLY 445
                   ND++          P+   +DY    CV  MI GKQ   +G    +A  +L 
Sbjct: 421 GCGQPMLLNDEIWITNMKKLGYPEDQANDYYNMGCVEIMIPGKQPN-WGVTEAIAFPVLI 479

Query: 446 AINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKY 505
                  E++  + G     I     ++DE M+     MD   +              + 
Sbjct: 480 -------EEVMRKWGAGEIKI----RSFDEFMDAYLQEMDIAIEADRQEALQKKANMTER 528

Query: 506 SYEASLMALHDRDVIRTM-------------ACGIAGLSVAADSLSAIKY-----AKVKP 547
            Y+     L D  +                 +    G+  AADSL A+K       KV  
Sbjct: 529 CYDPFSSVLIDGCLEHGKDMLQGGSECPVHWSVYAYGIGTAADSLCAVKKFVFDDQKVTL 588

Query: 548 IRDEDGLAIDFEIEGEY--------PQFGNNDPRVDDLAVDLVERFMKKIQKL-HTYRDA 598
            + +D L  DFE   E         P +GN    VD +A  ++  F K + +L H     
Sbjct: 589 EQMKDALEADFEGYEELRAMLDRMTPAYGNGLEEVDSIADKVLTHFSKSVFELNHNSEKD 648

Query: 599 IPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFA 658
               ++     ++ +G+  G TP+GR  G PF     P  G+D KG    L SV +L   
Sbjct: 649 KYVSTLFGYFFHIYHGEIVGATPNGRHKGEPFSDSMGPGQGKDVKGPTRLLHSVIRLNDD 708

Query: 659 YAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLD 718
           Y   G +  + + P  L   +E  +     L+  Y  +      G  + V   N + + D
Sbjct: 709 YITGGYALNYKLNPAFLN--EEKGRQAAISLLKTYIENR-----GPQIQVYTTNLDDIKD 761

Query: 719 AMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTF 756
           A  +PEK+  L +RV GY   F +L +  Q ++I RT 
Sbjct: 762 AQVHPEKHRDLIVRVGGYCEFFVNLDRVLQNEIIARTM 799


>UniRef50_B8FEM4 Formate C-acetyltransferase n=5 Tax=Proteobacteria
           RepID=B8FEM4_DESAA
          Length = 832

 Score =  438 bits (1126), Expect = e-121,   Method: Composition-based stats.
 Identities = 142/730 (19%), Positives = 270/730 (36%), Gaps = 103/730 (14%)

Query: 115 GIKMIEG-------SCKAYNRELDPMIKKIFTEYR-KTHNQGVFDVYTPDILRCRKSGVL 166
           G  M+                E    + ++   +  +T    V  +  P+      SG +
Sbjct: 117 GASMVNEEAYNEPGIMPEPENESLQKVAELNDYWAGQTAVDKVARILDPEDAVKFLSGAI 176

Query: 167 TGLPDAYGRGRIIGDYRRV--ALYGIDYLMK-------------------------DKLA 199
                +   G    DY  +     G + +++                         D+L 
Sbjct: 177 GWGAPSSAYGYSGKDYEYLFAGRRGFEDIIEEINAAIEKAEDKTVGVPGPEILDIYDRLQ 236

Query: 200 QFTSLQADLENGV-NLEQTIRLREEIAEQHRALGQMKE----MAAKYGYDISGPATNAQE 254
            + ++   LE G+ + ++  RL   +AE      + +E    +A       +    N QE
Sbjct: 237 NWDAMILVLEAGIRHAKRYARLARTMAENMETDEKRREELLKIAETCERVPARAPRNLQE 296

Query: 255 AIQWTYFGYL-AAVKSQNGAAMSFGRTSTFLDVYIERDLKAGK-ITEQEAQEMVDHLVMK 312
           ++Q+ +F  + A  ++  GA     R   +   Y ++D+   K +T+++A ++V   +++
Sbjct: 297 SLQYDHFIQIFARTEAHEGAW--PARPDYYHGPYYDKDVNVDKTLTKEDALDLVGEFMIR 354

Query: 313 LRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNM 372
              V         E   G       ++GG+  DG       +  FL     +  S  P  
Sbjct: 355 AYEVGGFAPRWAREGLQGITGTWVWTLGGVNKDGSDACNDLTVAFLQAARLVRVS-NPTF 413

Query: 373 TILWSEKLPLNFKKFAAK-VSIDTSSLQYENDDLMR---------PDFNNDDYAIACCVS 422
              W  K+     +   + +          ND L+          P      +    C+S
Sbjct: 414 GFRWHPKVKDEVLRECFECIRHGLGYPSMRNDPLLIQNAMHWHGHPLEEARTWVHQACMS 473

Query: 423 PMIVGKQ----MQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVME 478
           P    K     M+   A AN AK + YA++ G D  + MQ+GP++        +++++ +
Sbjct: 474 PCPTTKHGVQPMRMASATANCAKMVEYALHNGYDHVVGMQMGPETGD-AAKFHDFEDLFQ 532

Query: 479 RMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTM----------ACGIA 528
                M+WL    +  +N+  Y   ++     L  + +R V   +           C + 
Sbjct: 533 AWVKQMEWLTSLLVRTVNLGRYKDPEFFGRPFLSGMSERSVESGLDVVSPVGDRGNCWVT 592

Query: 529 GLSVA--ADSLSAIK---YAKVKPIRDEDGLAIDFEIEG----------EYPQFGNNDPR 573
             +     DSL+A+K   +   K   ++   A+    +G            P++GN+D  
Sbjct: 593 AFTWVENIDSLAAVKKLVFDDKKYTMEQLLTALKANWDGYEEMRLDFVNNAPKWGNDDDY 652

Query: 574 VDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTI-----TSNVVYGKKTGNTPDGRRAGA 628
           VDD+ +        +    H+     P+ +   I     + N+ Y    G  P+GRR G 
Sbjct: 653 VDDIMLR-----CLRETARHSRVMKCPSGNSWPILPENVSGNIHYASIVGALPNGRRCGD 707

Query: 629 PFGPG-ANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLA 687
               G  +P  G D+KG  A L S  K+              + P  L  +   +     
Sbjct: 708 ALYDGGISPGPGLDKKGPSAVLKSCGKIDHVSDGRAFLLNQRLSPTQLAGEKGYQ----- 762

Query: 688 GLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQ 747
            L   Y    A + G  H+  N+++ E L  A ++PEKY ++ +RV+GY+  F  ++++ 
Sbjct: 763 -LWKAYIRTWADL-GLDHVQFNMVSDETLRAAQKDPEKYSEVIVRVAGYSAHFVDISRKT 820

Query: 748 QQDVITRTFT 757
           Q ++I RT  
Sbjct: 821 QDNIIQRTVQ 830


>UniRef50_Q38HX4 4-hydroxyphenylacetate decarboxylase glycyl radical subunit n=3
           Tax=Clostridiales RepID=Q38HX4_9CLOT
          Length = 897

 Score =  412 bits (1058), Expect = e-113,   Method: Composition-based stats.
 Identities = 129/688 (18%), Positives = 239/688 (34%), Gaps = 116/688 (16%)

Query: 175 RGRIIGDYRRVALYGIDYLMK---DKLAQFTSLQAD-----LENGVNLEQTIRL------ 220
           +GR + +Y     YG D ++K   +K+A+      D     +  G        +      
Sbjct: 221 QGREVINYYMPLQYGFDGIIKLCDEKIAEVMGEAGDDGDFGMSRGYYYAAMKEITKGLSA 280

Query: 221 -REEIAEQHRALGQMK----------EMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKS 269
             E  +++ + L  ++          ++    G        N  EAIQ T   +   V  
Sbjct: 281 WCENYSKRAKYLASIETDSEIKANYEKIEEVMGNIAHKKPANFWEAIQMTLCCHFGVVNE 340

Query: 270 QNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFS 329
              + +S GR    L  + E+D++ G +T++E  E+++   +K+  +    +        
Sbjct: 341 DPQSGLSIGRLGQVLQPFYEKDVEDGIMTDEEVIELLELYRIKITCIECFASAGVSGGVL 400

Query: 330 GDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAA 389
               +   S+GG   DG + VT   +  +        +P+P +++L+ EK P +F   AA
Sbjct: 401 SGNTFNNLSLGGQNYDGLSAVTPLEYLIVEA-GMRNQTPQPTLSVLYDEKTPEDFLMKAA 459

Query: 390 KV-SIDTSSLQYENDDLMR---------PDFNNDD---YAIACCVS-------------- 422
               +      + N+                +  D   + +  C+               
Sbjct: 460 SCTKLGLGYPAWMNNQTGMNFMMRNYGPEGMDLHDARAWCLGGCLESAPGCFLPLEYNGK 519

Query: 423 -PMIVGKQMQFFGA---RANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVME 478
             MI G      G       + K +   +  G+D++   QV P   P    + +Y+ ++ 
Sbjct: 520 VTMIPGGASPTCGTGVHFIGMPKVLELVLTNGLDKRTGKQVYP---PHNKKLDSYETMVN 576

Query: 479 RMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGI----------- 527
           +   +M+          NI   +  KY+  A    L      +    G            
Sbjct: 577 QWKEYMELTTDVVNRCNNIQMDIWRKYNMPAVNSLLKPDCFKKGKHIGTMGARYNSCINF 636

Query: 528 --AGLSVAADSLSAIKYAKVKPIR-----DEDGLAIDFEIEG------------------ 562
              G     +SLS+IK       +       D +  +F  +                   
Sbjct: 637 ESCGTITFVNSLSSIKKNVFDDSKFTIEEMTDAMLNNFGFKTAYETEVFSPDFRESTDKS 696

Query: 563 -----------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNV 611
                        P++GN D   D++             K  +Y         ++++++ 
Sbjct: 697 TKYEKIFAACVNAPKYGNADKYADEIFKAYHYYIYDMTHKFRSYYGKPLYLCQISVSTHG 756

Query: 612 VYGKKTGNTPDGRRAGAPFGPG-ANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSI 670
             G  T  T DGR AG  +  G  +   G D+ G  A   S      +  ++       +
Sbjct: 757 PQGFVTLATADGRLAGTTYSDGSVSAAAGTDKNGIYAIFESATVYDHSMHQN-AQMNLKL 815

Query: 671 VPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLT 730
            P A+   +  RK  L  L+  Y       +GG H+  NV++ + L DA   PEKY +L 
Sbjct: 816 HPTAVKGINGTRK--LLDLVRAYMR-----KGGFHVQFNVVDSKTLRDAQLTPEKYRELM 868

Query: 731 IRVSGYAVRFNSLTKEQQQDVITRTFTQ 758
           +RV+G+   +  + K  Q +VI RT   
Sbjct: 869 VRVAGFTQYWCEIGKPIQDEVIYRTEYD 896


>UniRef50_A7VPJ9 Putative uncharacterized protein n=1 Tax=Clostridium leptum DSM 753
           RepID=A7VPJ9_9CLOT
          Length = 725

 Score =  405 bits (1042), Expect = e-111,   Method: Composition-based stats.
 Identities = 151/692 (21%), Positives = 264/692 (38%), Gaps = 86/692 (12%)

Query: 117 KMIEGSCKAYNRELD---PMIKKIFTEYRKTHNQG--VFDVYTPDILRCRKSGVLTGLPD 171
           ++I  + +    E D   P +K  ++        G  V+  YT           L   P 
Sbjct: 67  RIIGRAYQVRFAEPDCYDPELKD-YSLQSPGFESGEAVYKGYT-----DLAELHLVTEP- 119

Query: 172 AYGRGRIIGDYRRVALYGIDYL---MKDKLAQFTSLQAD-LENGVNLEQTIRLREEIAEQ 227
              RG I  D+ ++   G + L    ++ L     L+A+    GV +   +   E+  +Q
Sbjct: 120 --ARGHITWDWTKILRLGTEGLKAQYENALHSAKDLEAEHFYRGVLI--ALEALEDWNDQ 175

Query: 228 HRALGQM---KEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFL 284
           H A  +    +E+A    +    PA   +EAIQ  +  YLA            G+   +L
Sbjct: 176 HVAYLRKMGKQELADLCQHVPRHPARGFKEAIQSFFMQYLAVFYENPFGGNGPGQFDKYL 235

Query: 285 DVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESI-GGMG 343
             Y+++DL+ G  T +EA+E+V+ L ++L           DE  S + +W    I GG  
Sbjct: 236 WPYLKKDLENGSCTLEEAEELVEELFIRL-----------DERVSANDLWNEMIITGGTH 284

Query: 344 LDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAK----------VSI 393
            DG + V+  S   ++ +  +  +  P + +   +     + K  AK          +  
Sbjct: 285 RDGSSAVSPLSKIMVDAIMKLNIT-HPTVYMRVPKDADEEYVKLCAKYLKYGNNRAQIYY 343

Query: 394 DTSSLQYENDDLMRPDFNNDDYAIACCVSPMIVGKQMQFF-GARANLAKTMLYAINGGVD 452
           D + ++   +       +  +Y +  C+   I G        A  N+   +  AI GG  
Sbjct: 344 DPNVIRALTETDGVRPEDATEYGVGGCLEIGIQGMNDDLLQCAWVNMPLMLELAITGGYS 403

Query: 453 EKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHY--MHDKYSYEAS 510
              + QV     P+ G +  ++       +++D+  +    + ++I    +HD+    A 
Sbjct: 404 LSERKQVDSAGIPLPG-LAQHNTFESFYKNYLDFTDRLVGISFSMIERQSIHDEKYRPAY 462

Query: 511 LMALHDRDVI---RTMACGIA----------GLSVAADSLSAIKYAKVKP---IRDEDGL 554
           L++    D +   R M  G A          G+    D L AI+ A         +E   
Sbjct: 463 LISSMIDDCLERGRHMHAGGARYHDYSMTPLGIPNVIDGLYAIRTAVFDQHICTAEELVS 522

Query: 555 AIDFEIEG---------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVL 605
           A+  + +G           P++G  +   DD A  +V    K           I    VL
Sbjct: 523 AMRADFKGYERLQRQLRAIPKYGQENDDADDFARTVVTDIAKMFVTRRNRFGGIFRPMVL 582

Query: 606 TITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGIS 665
           T     +   + G T DG         G  P       G  A++ S  K+PF Y   G S
Sbjct: 583 TFIYAPLAAAQLGATADGNNMHTMVAQGLTPQSRSMSCGITAAMNSCTKMPFYYFSGGAS 642

Query: 666 YTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEK 725
             + + P+         +  +A L+  +FH+     G Q    N  + + L++A ++PE 
Sbjct: 643 TMWDLDPHW------ASEKLIADLLMTFFHN-----GAQVFQGNTTDVKELIEAQKHPED 691

Query: 726 YPQLTIRVSGYAVRFNSLTKEQQQDVITRTFT 757
           Y  L +RV G++ RF  LT   Q D+I R   
Sbjct: 692 YEHLIVRVGGFSARFVGLTPGLQTDIINRRRH 723


>UniRef50_D1ANR4 Formate C-acetyltransferase n=1 Tax=Sebaldella termitidis ATCC
           33386 RepID=D1ANR4_SEBTE
          Length = 768

 Score =  405 bits (1040), Expect = e-111,   Method: Composition-based stats.
 Identities = 136/627 (21%), Positives = 250/627 (39%), Gaps = 78/627 (12%)

Query: 181 DYRRVALYGIDYL---MKDKL---AQFTSLQADLENGVNLEQTIRLREEI-AEQHRALGQ 233
           DY ++   GID L   +KDKL   A+   L+  LE     E+T+    ++ A+  +  G+
Sbjct: 172 DYPKLLDNGIDGLKNIIKDKLNKSAENEFLKIALETLDLYEKTVDYERKLIAKAMKNAGE 231

Query: 234 --MKEMA---AKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYI 288
             +KE+           +       +A+Q  +   L          +++GR   +L  Y+
Sbjct: 232 ERLKELLLIDESLSAIRNNKPKTFHQALQMFWLYALL------AGCINYGRLDDYLGPYL 285

Query: 289 ERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRT 348
           + DL+ G ITE++A   +  L     ++   RT     + +G         G   ++   
Sbjct: 286 KHDLETGLITEEDAYRYLKSLW---TLIENRRTTVNGRIITGG-------YGRKNIEAAD 335

Query: 349 LVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFA-AKVSIDTSSLQYENDDLMR 407
           + T+ + +       +    EP  T+  +++ P +    A   +    +     ND++  
Sbjct: 336 IFTRIALKVTKDCKYV----EPQFTLRITKETPQDIMDMAYDCIGEGVTYPTLYNDEINI 391

Query: 408 PDFN---------NDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQ 458
           P             + Y    C   +I G+ +       NL K +   +N G+D     +
Sbjct: 392 PAVMYSMRVDRETAEQYVPFGCGEFVIQGQSVGTPNILINLLKILNITLNKGIDPMDGKK 451

Query: 459 V-GPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDR 517
             G        +  ++DE+  +    +D+       A    + + ++         L + 
Sbjct: 452 KSGNIIMKDPDEYRSFDELYSKYKELLDYYLDLSADAQYHSYEVMNREVSFMFASILTND 511

Query: 518 DVIRTMACGIAGL------------SVAADSLSAIK---YAKVKPIRDEDGLAIDFEIEG 562
            + R  +    G+              ++D+L AIK   + + K    E   A     +G
Sbjct: 512 CISRGKSILDGGVRYLGGTNETYGNINSSDALYAIKTLVFDQKKYTLKELNEAAHHNFKG 571

Query: 563 ---------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTIT-SNVV 612
                       ++GN+    D+LA DL E   K  +     +       V++   +N  
Sbjct: 572 YEKIREELWNCGKYGNDIEEADELANDLYEFVAKGNRDRGLKKGMDYFLIVISNNQTNTE 631

Query: 613 YGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVP 672
           +G+KT  + DGR +G    P  NP  G D+ G  A L S+++   A    G        P
Sbjct: 632 WGRKTSASLDGRYSGQFMNPANNPQGGADKNGPTALLNSLSRFD-AKYHGGSVQNIKFTP 690

Query: 673 NALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIR 732
           N   K+ ++    +  L D YF      +GG HL V V++R +L DA ++PEKYP L +R
Sbjct: 691 NMFNKNRKI----IKSLFDTYFK-----KGGCHLMVTVVDRGVLKDAQDHPEKYPDLVVR 741

Query: 733 VSGYAVRFNSLTKEQQQDVITRTFTQS 759
           VSG++  F +L ++ Q +V++R    +
Sbjct: 742 VSGFSAIFVNLERDVQDEVMSRVLYDA 768


>UniRef50_C5EHI0 Pyruvate formate-lyase n=8 Tax=Bacteria RepID=C5EHI0_9FIRM
          Length = 703

 Score =  402 bits (1032), Expect = e-110,   Method: Composition-based stats.
 Identities = 146/731 (19%), Positives = 270/731 (36%), Gaps = 109/731 (14%)

Query: 89  YINKQLEKIVGLQTEAPLKRAL-IPFGGIKMIEGSCKAYNRELDPMIKKIFTEYRKTHNQ 147
           Y+ ++++K    + ++P   A      G+  +E S K     L+     +F + R    +
Sbjct: 12  YVVQKIQKRFRREKDSPYALAEDFHEQGLSGLERSVKRLTYMLEQERPVVFKDERIGLIR 71

Query: 148 GV---FDVYTP-DILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQ--- 200
            V   ++++T  +    +K   +           I   Y  +   G D + ++   Q   
Sbjct: 72  TVPVNYEIFTEDEWKEIKKDHYIHEQGKVC---NINPRYGLLLDRGFDAVRREIERQKGM 128

Query: 201 ----------------------FTSLQADLENGVNLEQTIRLREEIAEQHRALGQMKEMA 238
                                    L A  E    +E       E A++        EMA
Sbjct: 129 YALDGQGGPSAQGTGHGFESESLRYLNALTETLDAIEAFAGRYGEEAQRAGNP----EMA 184

Query: 239 AKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKIT 298
             +G+          EA+Q+    +     S N    +FGR   ++  Y + D+++G++T
Sbjct: 185 RVFGHIPKQRPGTFMEALQFLRLLHYCLWCSFN-YHNTFGRFDQYMYPYYKADMESGRLT 243

Query: 299 EQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFL 358
           ++EA E+++   +       L    Y  +  GD    +  +GG+  DG     + S   L
Sbjct: 244 KEEALELLEEFFISCNKDSDL----YPGMQQGDN-GQSMVLGGLNPDGSDSFNELSDLCL 298

Query: 359 NTLYTMGPSPEPNMTILWSEKLPL-NFKKFAAKVSIDTSSLQYENDDLMRPDF------- 410
                +    +P + +  ++  PL  +++            QY NDD++ P         
Sbjct: 299 QASLEL-KLIDPKINLRVNKDTPLARYERGTQLTRQGLGFPQYANDDVVIPCLRHWGYAE 357

Query: 411 -NNDDYAIACCVSPMIVGKQMQFFGAR-ANLAKTMLYAINGGVDEKLKMQVGPKSEPIKG 468
            +  DY +A C   +I G  M        + A  +L  +               S P  G
Sbjct: 358 KDAYDYVVAACWEFIIPGTGMDIPNVNGLSFAAVVLDVL--------------DSLPGCG 403

Query: 469 DVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIR------- 521
               ++  M+++   +      +  A  +   +H+ Y   A LM+L     +        
Sbjct: 404 ---TFEAFMDKVKGEI------FRMAGELCDSVHNVYMEPAPLMSLMMDGCVERARDISK 454

Query: 522 -----TMACGIAGLSVAADSLSAIK---YAKVKPIRDEDGLAIDFEIEG----------E 563
                       GLS A DSL+AI+   Y       +E    +D + +G          +
Sbjct: 455 GNLYNNYGFHGTGLSTAVDSLAAIRKYVYEDRMFTAEELLKMLDADFKGYEDIQNMLRYQ 514

Query: 564 YPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDG 623
            P+ GN+D RVD+LA  L++ F   ++  +     I      +    V + +    TPDG
Sbjct: 515 SPKMGNDDDRVDELATRLLDWFADSLEGRNNDMGGIFRAGTGSAMYYVWHSRNQHPTPDG 574

Query: 624 RRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRK 683
           R  G       +P      +G V+ + S +K       +G   T  +  +    +D +RK
Sbjct: 575 RNEGEELACNYSPSLFTRLEGPVSIIKSFSKPHLERVANGGPLTIELHDSMFRNEDSIRK 634

Query: 684 TNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSL 743
             +   +  +        GG  + +N +NRE +LDA E+PE +  L +RV G++  F  L
Sbjct: 635 VAV--FVKSFMDM-----GGHQMQINAVNRETMLDAKEHPENHKNLIVRVWGWSGYFVEL 687

Query: 744 TKEQQQDVITR 754
            +  Q  +I R
Sbjct: 688 DEVYQNQIIKR 698


>UniRef50_B0NGB8 Putative uncharacterized protein n=3 Tax=Bacteria
           RepID=B0NGB8_EUBSP
          Length = 794

 Score =  397 bits (1020), Expect = e-109,   Method: Composition-based stats.
 Identities = 147/648 (22%), Positives = 251/648 (38%), Gaps = 83/648 (12%)

Query: 176 GRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLENGVNLEQT----------IRLREEIA 225
           G +I D R V   G+D L K+++ +  + +AD +     +                EE+A
Sbjct: 163 GHLIPDMRPVLKIGVDGL-KEQIRRHKAAEADADKKDYYDAMDIALDAVLVIAGRYEELA 221

Query: 226 EQH--RALGQMKE----MAAKYGYDISGPATNAQEAIQWTYFGY--LAAVKSQNGAAMSF 277
            +   ++ G +KE    MA   G      A+N  EAIQ     +  +   ++ N  A S 
Sbjct: 222 REKAAKSEGAVKERFEVMADALGKVPRQGASNLYEAIQSFILMWQVMCLEQTPNPYAFSV 281

Query: 278 GRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATE 337
           G      + Y        +  E   ++M   L+  L  + F    +     S        
Sbjct: 282 GNADRIFEPY--------RQAEDTGRDMTAALLKHL--LVFYNVADRSWAIS-----QDL 326

Query: 338 SIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSS 397
            IGG    G  +    S+  L+  Y M   P+P +++   +  P    +   +       
Sbjct: 327 IIGGKSNTGEDMTNPTSYALLDAYYDMN-LPQPILSVKLHKDTPDELYESLGRFLFTPGC 385

Query: 398 --LQYENDDLMRPDF---------NNDDYAIACCVSPMIVGKQMQ-FFGARANLAKTMLY 445
               + NDD +             + +DY++A C  P+I+GK       +  N+AK +  
Sbjct: 386 LTPSFFNDDSVFEILKEKNHVEPEDLEDYSVAGCQEPLIMGKDNGNTTNSWLNMAKVLEL 445

Query: 446 AINGGVDEKLKMQVGPKSE----PIKGDVLNY--DEVMERMDHFMDWLAKQYITALNIIH 499
           ++NGGV      + G  +E      + DVL        + ++ ++D + +    A   I 
Sbjct: 446 SLNGGVSTISGRKFGKSNEENGYKEEVDVLKNIRSTFYQNLEEYVDQMVECANAASEAIS 505

Query: 500 YMHDKYSYEASLMALHDRDV-----------IRTMACGIAGLSVAADSLSAIKYAKVKPI 548
            +  +  + ++LM   +  +                C I GLSV ADS +AI     +  
Sbjct: 506 LL--QVPFLSALMGGIETGIDTRDTRNQGTKYNGSGCLIHGLSVVADSFAAIDRLLEERP 563

Query: 549 RDE----DGLAIDFEIEGEYP-------QFGNNDPRVDDLAVDLVERFMKKIQKLHTYRD 597
           +D     + L  +FE + +         ++GNN   VDD A ++  R    +     Y  
Sbjct: 564 KDAGRMLEALRDNFEHDQQMRQYLMKAEKYGNNTANVDDEAAEIAARVSDMVSSKKNYLG 623

Query: 598 AIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPF 657
                   + +++++YG   G TPDGR A    G G +P++G    G    + S  KLPF
Sbjct: 624 NPFRADWASPSTHLLYGYWVGATPDGRMAREQLGYGIDPLYGEAHSGLGFRIMSNMKLPF 683

Query: 658 AYAKDGISYTFSIVPNALGKDD-EVRKTNLAGLMDGYFHHEASIEG--GQHLNVNVMNRE 714
                G +    I PN       E +       + G   +    EG    +L VNV   E
Sbjct: 684 EKMNGGCASHLGINPNYFKTSSYEEKGLEFKNKIIGPLFYNPKKEGISPFYLYVNVTTPE 743

Query: 715 MLLDAMENPEKYPQ---LTIRVSGYAVRFNSLTKEQQQDVITRTFTQS 759
           ML   + +P+KY       +R+ G  V F  L+ + Q+D+I R   +S
Sbjct: 744 MLRKVLADPKKYAPSGVYIMRIHGTFVNFLDLSPDIQEDIIKRLDMES 791


>UniRef50_B2V300 4-hydroxyphenylacetate decarboxylase, catalytic subunit n=12
           Tax=Bacteria RepID=B2V300_CLOBA
          Length = 905

 Score =  394 bits (1012), Expect = e-108,   Method: Composition-based stats.
 Identities = 137/752 (18%), Positives = 264/752 (35%), Gaps = 123/752 (16%)

Query: 115 GIKMIE--GSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDA 172
           G++  E     K     +D  +  +  +Y +              L C     +      
Sbjct: 171 GMRQEEIPVLVKLAKEWVDRSVDDLGHKYEQMVPDYEIKENIMKSLIC-----MFDSGFT 225

Query: 173 YGRGRIIGDYRRVALYGIDYLMK---------------------DKLAQFTSLQADLENG 211
             +GR + +Y     YG D L+                      D+L  + +++  LE  
Sbjct: 226 LPQGREVVNYYYPLQYGFDGLIDMAVECKKKVAGNADGDGLVGMDRLYFYEAVKITLEGI 285

Query: 212 ----VNLEQTIRLREEIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAV 267
               +N E+  R    I +      +  E+A    +         +EA+Q TY  ++A +
Sbjct: 286 QNWILNYEKHARDLALIEKNQSQKEEYIEIADCLNWIAHKQPRTFREALQLTYIIHIAVI 345

Query: 268 KSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDEL 327
                + +S GR    L  + ++D++ G+ITE+E  E+++   +K   +    +      
Sbjct: 346 NEDAISGLSPGRVGQVLYPWFKQDIENGRITEKEVLELLELHRVKFTCIDCFASTGVVGG 405

Query: 328 FSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKF 387
                 +   ++GG+  DG +   +  +  +    T   +P+P ++  + EKLP +F   
Sbjct: 406 VLSGNTFNNLTLGGLKKDGSSAANRLEYLIVEAGITCA-TPQPTLSCFYDEKLPEDFLLK 464

Query: 388 AAKV-SIDTSSLQYENDDLMRPDFNN------------DDYAIACCVSPM---------- 424
             +     +    + N+        N               AI  C+             
Sbjct: 465 CIECDKTGSGYPAWMNNRGAIEFMMNQYGDEGMTIEEARSVAIGGCLETSPCTWKELTLN 524

Query: 425 -----IVGKQMQFFGARANL---AKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEV 476
                I G   Q      +     K +   +  G D +  +QV P+       +  +++V
Sbjct: 525 GEKFDIPGGAGQPTSVGVHFIANPKVLELVLTNGKDYRTNLQVYPEH---NRKLETFEDV 581

Query: 477 MERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACG---------- 526
           + +   + +          NI H +  K +       L    +      G          
Sbjct: 582 VNQFKEYYELTCDVLAKTNNIQHDIWRKKNMSIVNSLLKPNCLDVGKHIGNLGYRFNATY 641

Query: 527 ---IAGLSVAADSLSAIK---YAKVKPIRDE--DGLAIDF-------------------- 558
                G     +SL+++K   Y   K   DE  + +  +F                    
Sbjct: 642 NVESCGTINTINSLASLKKLVYDDKKYTLDEMREAILNNFGFKTAEEIGSYSLADQEKAG 701

Query: 559 ------EIEGEY---PQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITS 609
                 +I G+    P++GN+DP VD +  D  + F        +          +++++
Sbjct: 702 ISSKYDDIYGDCLLAPKYGNDDPYVDSILKDYEDWFCDVCHNYESLYGKKMYACQISVST 761

Query: 610 NVVYGKKTGNTPDGRRAGAPFGPG-ANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTF 668
           +   G  T  T DGR AG  +  G  +   G D+ G  A  TS      + +++      
Sbjct: 762 HGAQGAATLATTDGRLAGTTYADGSMSAYPGTDKNGPYALFTSATVWDHSKSQN-SQMNL 820

Query: 669 SIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQ 728
            I P+A+   +  +K  L  L   Y       +GG H+  NV++ ++L +A   PE Y  
Sbjct: 821 KIHPSAIKGIEGSKK--LLDLTRSYMR-----KGGYHIQYNVVDSKVLKEAQVKPESYRD 873

Query: 729 LTIRVSGYAVRFNSLTKEQQQDVITRTFTQSM 760
           L +RV+G+   +  + K  Q +VI+RT  + +
Sbjct: 874 LMVRVAGFTQYWCEIGKPIQDEVISRTEYEGV 905


>UniRef50_B0CLU5 Alpha-subunit of naphtylmethylsuccinate synthase n=4 Tax=Bacteria
           RepID=B0CLU5_9DELT
          Length = 828

 Score =  386 bits (991), Expect = e-105,   Method: Composition-based stats.
 Identities = 136/753 (18%), Positives = 269/753 (35%), Gaps = 98/753 (13%)

Query: 93  QLEKIVGLQTEAPLKRALIPFGGIKMIEGSCKAYNRELDPM---IKKIFTEYRKT-HNQG 148
             E IVG   E P   A+ P  G        +      D +    ++I   ++       
Sbjct: 85  DEEFIVGDAAENPDTLAIFPEMGFFPTIDIVEDPELMDDDIRDEAREIAMFWKPLGLQDK 144

Query: 149 VFDVYTP-DILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMK------------ 195
               Y   +I       ++   P       +   Y  V   G+   +K            
Sbjct: 145 CMPYYDQHEIDIATPWTIVDVPPFIANYMSVCPAYMSVLEDGLLGRIKSAEENIEKAFVK 204

Query: 196 ---------------DKLAQFTSLQADLENGVN-LEQTIRLREEIAEQ----------HR 229
                          D++  + ++    +  +    +  RL + +AE             
Sbjct: 205 LRAYPWNGPENMPLMDQIDVWRAMIIADKAVIKWARRYSRLAKIVAENFDLSDSVQGAEE 264

Query: 230 ALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRT-STFLDVYI 288
              ++ E++       + PA   ++A+Q  +F YL    S    +  +       +  Y 
Sbjct: 265 RKNELLEISDICYRMPAEPAKGFKDAMQSKWFVYLVCH-SLERYSSGYAHLEDRLMWPYY 323

Query: 289 ER---DLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLD 345
           +    D  A  +T  EA ++V+   +K+      +   + E   G       +IGG+  +
Sbjct: 324 KASVIDKTAQPMTRDEAIQLVELERLKVCERGVAKGRAHREGQPGANDLHIITIGGLDEN 383

Query: 346 GRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAK-VSIDTSSLQYENDD 404
           G       +   L     +  +PEP++   +S K+    ++   + ++        ++++
Sbjct: 384 GNDATNDLTNVILEASLNI-RTPEPSLGFRYSPKINAKTRRLVFENIAAGFGFPSIKHEE 442

Query: 405 ---------LMRPDFNNDDYAIACCVSPMIVG-----KQMQFFGARANLAKTMLYAINGG 450
                       P      +A+  C++P +       K     G    + K    A   G
Sbjct: 443 KNTRQMLEHYKVPPDEAAHWALVLCMAPGVSKRRGLQKTRTEGGGLIWIDKCCEIAFYDG 502

Query: 451 VDEKL-KMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEA 509
            D     +Q GPK+         ++E+ E  +  +++    +    ++      K+    
Sbjct: 503 FDHSFANIQTGPKTGDAT-KFKTFEELFEAFEKQVEFATALHYRNKDVTRRAEIKFIESP 561

Query: 510 SLMALHDRDVIRTMACGI-----------AGLSVAADSLSAIK---YAKVKPIRDEDGLA 555
            + +L D  +   +   +            G   AADSL+A+K   +   K   +E   A
Sbjct: 562 FVASLDDACMDDGVGAFVDKTYPNPWNNTPGEQTAADSLAAVKKLVFDDKKYTMEEVVNA 621

Query: 556 IDFEIEG---------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLT 606
           +    +G           P++GN+DP VD++   + +    K+ +  TY    P  +  T
Sbjct: 622 MKANFDGYEEMRKDMLAAPKWGNDDPYVDEIGERVFKMVADKLMEQTTYSGMHPLGNPQT 681

Query: 607 ITSNVVYGKKTGNTPDGRRAGAPFGP-GANPMHGRDQKGAVASLTSVAKLPFAYAKDGIS 665
           +++      + G  P G+  G      G++P  G D+KG  A L SVA +P+   K G+ 
Sbjct: 682 VSTFATRAPRIGALPFGKLHGEVLHDGGSSPYVGLDKKGPTAVLKSVAHIPYDRYK-GVQ 740

Query: 666 YTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEK 725
           +   +  + +  D   +      +   Y      +    H+  NV+  + +L+A + PEK
Sbjct: 741 FNQRLPVSIMRGDKGFQ------VWSAYMKAWHDLN-IDHVQFNVVETKDMLEAQKEPEK 793

Query: 726 YPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQ 758
           +  L +R++GY+ RF SL K  Q  +I R   Q
Sbjct: 794 WESLIVRIAGYSARFVSLPKNAQDAIIARNEQQ 826


>UniRef50_C0CUZ2 Putative uncharacterized protein n=1 Tax=Clostridium asparagiforme
           DSM 15981 RepID=C0CUZ2_9CLOT
          Length = 759

 Score =  377 bits (967), Expect = e-102,   Method: Composition-based stats.
 Identities = 126/628 (20%), Positives = 223/628 (35%), Gaps = 85/628 (13%)

Query: 181 DYRRVALYGIDYLMKDKLAQFTSLQADLENGVNL------------------EQTIRLRE 222
           D+ ++   G+  +  +  A     + +  + V                    +Q + L  
Sbjct: 162 DFDKLIRLGLPGMRAEVTAYRERAEQEGGDAVLYQCMDGALELMGQVCLWYRDQAMELLA 221

Query: 223 EIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTST 282
           +  ++ R  G+++ MA            +  EA+Q  +   + A        + FGR   
Sbjct: 222 QAGDEKRK-GELRRMAQALEAIAERAPGSMMEALQLVWIYGIMAPL------LQFGRLDV 274

Query: 283 FLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGM 342
           +L  +   D+  G +TE+EA  ++     ++  +                      +GG 
Sbjct: 275 YLGDWYAHDIDNGVLTEEEALALLQSYFRQIDSL-------------DSETDCRVIVGGY 321

Query: 343 GLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAK-VSIDTSSLQYE 401
           G        +     L    T+     P  T+ ++ + P      A + +    +     
Sbjct: 322 GRRNPENADRLCMTALEACRTV-REILPQFTLRFNRETPECVWDAAMRCIEEGRTYPLLY 380

Query: 402 NDDLMRPDFNN---------DDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVD 452
           NDD++ P   N         + Y    C                 N  K +  A+ GG +
Sbjct: 381 NDDVLVPGLMNAFHVSRERAETYVPLGCGEMEFDHYSFGTPSGSLNTLKILELAVRGGYE 440

Query: 453 EKLKMQVGPKSEPIKGDVLNYDEVMERMD----HFMDWLAKQYITALNIIHYMHD----K 504
             +   +G + +PI      ++E  +       H+++  A        I   MH      
Sbjct: 441 PIMDWHLGKQLKPIT-QCNTFEEFFQVYKENLQHYIEAQAIFEKYEYEITGKMHSFMYVS 499

Query: 505 YSYEASLMA----LHDRDVIRTMACGIAGLSVAADSLSAIK---YAKVKPIRDEDGLAID 557
             Y+  L +                 + G+  A +SL+A+K   Y       ++   A++
Sbjct: 500 MLYDGVLESGKAIFDGGCRYLAGTLELYGVVNAVNSLAAVKKLVYEDRTVSAEDLLRAMN 559

Query: 558 FEIEG---------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSV-LTI 607
               G         + P++GN+D  VD + V+L +   K I             +V +  
Sbjct: 560 DNFVGWEVLRRQLLDVPKYGNDDDYVDRIFVELHDWLCKTISSQAEKVGLKSYLAVNINN 619

Query: 608 TSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYT 667
             N   G+  G TPDGR+AG P     NP  G D+ G  A L S+ K P      G+   
Sbjct: 620 AQNTTLGRWVGATPDGRKAGMPMANANNPSSGSDKNGLTAMLNSILK-PRHDNHAGMVQN 678

Query: 668 FSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYP 727
             +         E  +  + GL+  YF       GG HL + V+ +E L  AME+PE Y 
Sbjct: 679 LRLSRETF----EQNREKVKGLIRNYFD-----RGGAHLMITVVGKEDLKKAMEHPEDYQ 729

Query: 728 QLTIRVSGYAVRFNSLTKEQQQDVITRT 755
            L +RV G + R+  L K+ QQ++  R 
Sbjct: 730 DLIVRVGGLSARYVQLKKDVQQEIYDRA 757


>UniRef50_Q2C4S5 Formate acetyltransferase n=7 Tax=Gammaproteobacteria
           RepID=Q2C4S5_9GAMM
          Length = 280

 Score =  373 bits (957), Expect = e-101,   Method: Composition-based stats.
 Identities = 186/269 (69%), Positives = 226/269 (84%)

Query: 11  AWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLWDKVMEGVKLENRTHA 70
           AW+GF+ G+WQ EVN RDFIQ NYTPYEGDESFLA  TE TT+LW+ V+EG+K E+RTHA
Sbjct: 11  AWKGFSAGNWQQEVNTRDFIQTNYTPYEGDESFLADVTETTTSLWNTVLEGIKEESRTHA 70

Query: 71  PVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIKMIEGSCKAYNREL 130
           PVDFDT + STITSHDAGYINK LEKIVGLQT+ PLKR++I  GGI+M++ SC+ Y R+L
Sbjct: 71  PVDFDTDLPSTITSHDAGYINKDLEKIVGLQTDKPLKRSIIANGGIRMVKSSCEVYGRKL 130

Query: 131 DPMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGI 190
           D  ++KIFT+YRKTHN+  FD+YT +IL CRKSG++TGLPDAYGRGRIIGDYRR++LYGI
Sbjct: 131 DESVEKIFTDYRKTHNKACFDLYTKEILACRKSGIITGLPDAYGRGRIIGDYRRLSLYGI 190

Query: 191 DYLMKDKLAQFTSLQADLENGVNLEQTIRLREEIAEQHRALGQMKEMAAKYGYDISGPAT 250
           D+L  DK  Q+ S QA LE G +LE+T+RLREE+A+Q +AL  +++M  KYG D+S PA 
Sbjct: 191 DFLKSDKQEQYKSTQAFLEQGHDLEKTLRLREELADQVQALEDIRQMGLKYGIDMSAPAR 250

Query: 251 NAQEAIQWTYFGYLAAVKSQNGAAMSFGR 279
            AQEAIQ+TYFGYLAAVKSQNGAAMS GR
Sbjct: 251 TAQEAIQFTYFGYLAAVKSQNGAAMSLGR 279


>UniRef50_A5ZSK3 Putative uncharacterized protein n=1 Tax=Ruminococcus obeum ATCC
           29174 RepID=A5ZSK3_9FIRM
          Length = 745

 Score =  370 bits (949), Expect = e-100,   Method: Composition-based stats.
 Identities = 135/767 (17%), Positives = 254/767 (33%), Gaps = 101/767 (13%)

Query: 59  MEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGI-K 117
            E  K     ++    D +            + K+L++   LQ E P   +      I +
Sbjct: 10  EEYFKETKAVYSNYPTDVSR-----------MEKELDR---LQKENPKASSFQKKTWIYR 55

Query: 118 MIEGSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVY--TPDILRCRKSGVLTGLPDAYGR 175
                 +       P   +I T   +      F         L  +    + G  +  G 
Sbjct: 56  TAARDAEVILFPSSPFYAEIDTGREQNSVTASFPPQPGIGCWLMKQYPDFVDGYGEWSGY 115

Query: 176 ---------------GRIIGDYRRVALYGIDYLMKDKLAQF----------TSLQADLEN 210
                               +   +  YG+  +++    +             L+  ++ 
Sbjct: 116 YGKYGVMNGPQFMDAAHHYANCETILKYGLSGIIRHARMRLEEKDLTDHQQDFLKCMIDV 175

Query: 211 GVNLEQTIRLREEIAEQH-------RALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGY 263
             +L++      E AE+          +  +K +A       S PA    EA+   +F  
Sbjct: 176 CRSLQRISERFAEKAEEMLKTEHDEEHVKALKMIAVTARRIPSEPAETFYEAMCAIWFTR 235

Query: 264 LAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPE 323
                         G     L  Y ERDLK  +IT  EAQE++D   + +   R+    +
Sbjct: 236 EMCNALDGLGFAVIGHLDRILISYYERDLKNNRITPDEAQELIDCF-VSMTDARWNLEAD 294

Query: 324 YDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLN 383
                + D       IGG   +G  +    S   +N+ Y       P + +  S K P  
Sbjct: 295 LPGGTNAD-----IIIGGCDKNGDIVYNDISRMIINS-YKKYHFANPKLQVRISAKHPDE 348

Query: 384 FKKFAAKV-SIDTSSLQYENDDLMRPDFNNDD--------YAIACCVSPMIVGKQMQFFG 434
           F     ++  +  + L   NDD++ P              Y    C    +  +      
Sbjct: 349 FLLQVGELAGMGLNVLSIFNDDVIIPANQKQGKSLEDCRLYVAGGCQEICLSNEVNSRAY 408

Query: 435 ARANLAKTMLYAIN----GGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQ 490
              NL + +  ++       + ++   +  P +     +   Y  V+E   + +++  K+
Sbjct: 409 TYLNLVQMLNGSLYPEYWNDIFKRDGFEFLPAANASDFEEF-YHIVIENYRNELNFFVKK 467

Query: 491 YITALNIIHYMHDKYSYEASLMAL--------HDRDVIRTMACGIAGLSVAADSLSAIKY 542
           Y    +    ++    + A++ +             V  T     AG     DSL AIK 
Sbjct: 468 YNEYGSWWKIINPSLFFSATMPSCTETAKDVSEGGAVYNTDNFAAAGAGTVIDSLYAIKK 527

Query: 543 AKVKPIRDE-----DGLAIDFE--------IEGEYPQFGNNDPRVDDLAVDLVERFMKKI 589
           A  +            +  DF         +  + P+F  +     +    +++   + +
Sbjct: 528 AVYEDKITTFGHLLKAMKEDFRDDEILRQYLLHKVPKFCKDKD-ATEFGKKVMDDLAECL 586

Query: 590 QKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASL 649
                YR      S+    S   +   T  T DGR++ +    G NP    +     A L
Sbjct: 587 GGQANYRGGKFEPSLFAFYSYNWFKNVTIATADGRKSESALSRGVNPSESTENINIAALL 646

Query: 650 TSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVN 709
            ++  + +     G      I P         + +  A +M  +  +     GG  ++ N
Sbjct: 647 DAIKTMDYTKYPGGAVIYMDI-PLMYKTP---QPSLFASVMRAFCEN-----GGSIMDFN 697

Query: 710 VMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTF 756
           V++R  LL+A +NPE +  + +RV GY+  F++LT E Q +VI RT 
Sbjct: 698 VISRNALLEAQKNPETHKNIVVRVCGYSAYFHTLTAEMQNEVIQRTQ 744


>UniRef50_D1N5W4 Formate C-acetyltransferase n=1 Tax=Victivallis vadensis ATCC
           BAA-548 RepID=D1N5W4_9BACT
          Length = 783

 Score =  369 bits (948), Expect = e-100,   Method: Composition-based stats.
 Identities = 147/719 (20%), Positives = 246/719 (34%), Gaps = 95/719 (13%)

Query: 93  QLEKIVGLQTEAPLKRALIPFGGI---KMIEGSCKAYNRELDPMIKKIFTEYRKTHNQGV 149
           Q+E  VG      +   + P   I   ++   + + Y RE  P +K++   Y KT     
Sbjct: 96  QVESFVGYCDPVAIYADIEPSEAIPAERI--EAVRNYYRET-PYVKRLTAIYEKT----- 147

Query: 150 FDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLE 209
               T ++            P     G +I D R +   G++  +    A    +    E
Sbjct: 148 -AALTDEV-------TFFMEP---VTGHMIPDMRPILAQGLEAFVAAAPADTPFVAVMRE 196

Query: 210 NGVNLEQ----TIRLREEIAEQHRA----LGQMKEMAAKYGYDISGPATNAQEAIQWTYF 261
                         L E +AE+  A      ++K +AA         A N  EA+Q    
Sbjct: 197 AARAAAILAGRYAELAETLAEERAAMPGEAERLKLIAANCRQVPVRKARNLHEAMQSYLL 256

Query: 262 GY--LAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFL 319
            +  +   ++ N  A S G      + Y+      G    + A  +  HL++      F 
Sbjct: 257 LWQLMCLEQAPNPYAFSAGNLDRVFEPYLA---GTGF---ESAVALTRHLLV------FY 304

Query: 320 RTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEK 379
                    S         +GG  L G  L    +   L   +     P+P +++     
Sbjct: 305 MVGARGWAIS-----QNLLLGGRDLAGNDLGCGMTDVILEAFFRSNQ-PQPALSVKIHRN 358

Query: 380 LPLNFKKFAAKVSI--DTSSLQYENDDLM--------RPDFNNDDYAIACCVSPMIVGKQ 429
            P    +   +       S+    NDD+M          D +  D+A+A C  P+I+GK+
Sbjct: 359 SPERLFRNMGRFYFTPGHSTPSLFNDDMMFRVLKSKGIADADIPDWAVAGCQEPLIMGKE 418

Query: 430 MQ-FFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGD--VLNYDEVMERMDHFMDW 486
                 +  NLAK +   +N G       ++G  +  +  D     Y ++       +D 
Sbjct: 419 NGNTTNSWLNLAKVLELVLNDGCSLLTGRRIGLSAAELGYDSPEAAYRDLETAFFRQLDH 478

Query: 487 LAKQYITALNIIHYM-------HDKYSYEASLMALHDRDVIR------TMACGIAGLSVA 533
           +      A N                 +         RD  R         C I GL V 
Sbjct: 479 VLPFMEAAANRCTRAIGGWATPFGSLLFGGLESGRDMRDPERPGTRYSGSGCLIHGLGVV 538

Query: 534 ADSLSAIKYAKVKPIRDEDGL------------AIDFEIEGEYPQFGNNDPRVDDLAVDL 581
           ADSL A+K+   +     D L            A+   +   YP++G+  P  D+ A  +
Sbjct: 539 ADSLVAVKHFLAEQPGGADSLRAALRNNFADAPALRARLLA-YPKYGSVLPEPDETAARI 597

Query: 582 VERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRD 641
                 K+  L             T +++++YG   G TPDGR A A  G G +P     
Sbjct: 598 ASVVSDKVYALRNPAGRPFMPDFSTPSTHLLYGYWVGATPDGRPARAMLGYGVDPRPEVT 657

Query: 642 QKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLA---GLMDGYFHHEA 698
                  L S   LPF     G +    + P A     E+ +  +A    ++   F   A
Sbjct: 658 NSELTDQLLSERGLPFGKMVGGYASHIGLAPAAFADRAELEEKGVAMRDRVIRPLFAAGA 717

Query: 699 SIEGGQHLNVNVMNREMLLDAMENPEKYPQ---LTIRVSGYAVRFNSLTKEQQQDVITR 754
             E   ++  N+ + + L   + +P +Y       +R+ G  V F  L    Q+D+I R
Sbjct: 718 EGEAPYYVYFNIDSAKHLRKILTDPARYVPSGIYIMRIHGTFVNFLDLAPAIQEDIIKR 776


>UniRef50_D1N4L3 Formate C-acetyltransferase n=1 Tax=Victivallis vadensis ATCC
           BAA-548 RepID=D1N4L3_9BACT
          Length = 716

 Score =  367 bits (943), Expect = e-100,   Method: Composition-based stats.
 Identities = 134/620 (21%), Positives = 233/620 (37%), Gaps = 82/620 (13%)

Query: 177 RIIGDYRRVALYGIDYLMKDKLAQFTS----------LQADLENGVNLEQTIRLREEIAE 226
               DYR     G   L +       +          L A+LE    +   I      AE
Sbjct: 137 HFAPDYRIGLSLGWGGLTRKVERSLEAHKFDSEAVELLNAELEALAGIRNWIHRTAMAAE 196

Query: 227 QHRALGQMKEMAAKYGYDISGPATNAQEAIQWT-YFGYLAAVKSQNGAAMSFGRTSTFLD 285
                G+++ +  +   D   P    +EA QW  +F   +   +++GA    G+    L 
Sbjct: 197 -----GELRRINLRLEND---PPETLREACQWIAWFNMASRTYNRDGAG---GQLDEILR 245

Query: 286 VYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLD 345
            Y ERD+ AG+I +++A   +  L++          P Y +            IGG   +
Sbjct: 246 PYYERDIAAGRIDDEDAVYYIACLLL--------NDPHYYQ------------IGGPDPN 285

Query: 346 GRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSI--DTSSLQYEND 403
           G+   ++ SF  L   + +      N+TI   +++     +   ++ +  +    ++  D
Sbjct: 286 GKDQTSRISFLILEAAHALK--TPCNLTIRVHDRMDEKLFRRGVEILLEDNLGYPRFSGD 343

Query: 404 DLMRPDFNNDDYAIA--------CCVSPMIVGKQMQFFG-ARANLAKTMLYAINGGVDEK 454
           + +   F  + Y+I          C    I G++       + N+ K    A N   D  
Sbjct: 344 NALIEGFMRNGYSIELARERIALGCNWMSIPGREYTLNDTVKINMMKVFEVAFNEIADSG 403

Query: 455 LKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMAL 514
            K  +G   +  +  +      +     F   LA QY     ++  +      E    A 
Sbjct: 404 -KFSLGALHKCYQKHLARAAFCIAEGLDF--HLAHQYRNEPELLLNLLCYGPIEKGRDAS 460

Query: 515 HDRDVIRTMACGIAGLSVAADSLSAIKYAKVK---------------PIRDEDGLAIDFE 559
           H       M C  AGL+V ADS +A++   V+                 R+E+G  I   
Sbjct: 461 HGGVDFYNMCCDGAGLAVVADSFAALQTQVVERKRIAWKECVEAVRSDFRNENGEQIR-R 519

Query: 560 IEGEYPQFGNNDPRVDDLAVDLVERFMKKI-QKLHTYRDAIPTQSVLTITSNVVYGKKTG 618
           +    P+FG+     D+ AV L   F +       T    +    + +    + +GK  G
Sbjct: 520 LLASSPRFGHGGTCADEWAVTLTHDFAETFPNGRRTPEGRLIIPGLFSWADTLRFGKTVG 579

Query: 619 NTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKD 678
            TP+GRRAG P   GANP  G  + GA  ++            +       +  + +   
Sbjct: 580 ATPNGRRAGEPSSHGANPCPGFRKDGAATAVAKAVASVQCGYGNTSPLQLELDASFVNCA 639

Query: 679 DEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAV 738
           D V +  L  L   +F       GG  +NVN+++ + L  A + PEK+P L +RV+G+  
Sbjct: 640 DPVGR--LTALFRTHFKL-----GGTLINVNIVDAKTLRAAQKEPEKFPDLIVRVTGFTS 692

Query: 739 RFNSLTKEQQQDVITRTFTQ 758
            F  L+ E +  V+ R   +
Sbjct: 693 YFIMLSPEFRDFVVKRIIEE 712


>UniRef50_A9KN53 Pyruvate formate-lyase n=21 Tax=Bacteria RepID=A9KN53_CLOPH
          Length = 867

 Score =  363 bits (933), Expect = 1e-98,   Method: Composition-based stats.
 Identities = 110/529 (20%), Positives = 196/529 (37%), Gaps = 62/529 (11%)

Query: 90  INKQLEKIVGLQTEAPLKRALIPFGGIK-MIEGSCKAYNRELDPMI---------KKIFT 139
           + ++ E IVG  T A       P      +I        R  DP           +K+ +
Sbjct: 67  VIRENELIVGSATVAERGCQTFPEFSFDWLIAELDTVATRTADPFYISEEAKKELRKVHS 126

Query: 140 EYRKTHNQGVFDVYT-PDILRCRKSGVLTGLPDAY-GRGRIIGDYRRVALYGIDYLMKDK 197
            ++      + D Y  P+     +  V T     Y G G I   Y +V   G + +  + 
Sbjct: 127 YWKGKTTSELADYYMAPETKLAMEHNVFTPGNYFYNGVGHITVQYDKVIAIGYEGIKDEV 186

Query: 198 LAQFTSL---QAD-LENGVNLEQTIR-------LREEIAEQHRALG----------QMKE 236
           L++   L    AD        +  IR         +  A + + L           ++  
Sbjct: 187 LSRKKELHLGDADYASRLTFYDAVIRSCDSAILYAKRYAAEAKRLALSCQDEKRRQELLM 246

Query: 237 MAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGK 296
           +++      +  A    EA Q  +F  L      +G ++S GR   +L  Y + D +AG+
Sbjct: 247 ISSNCERVPAKGANTFYEACQAFWFVQLLLQIEASGHSISPGRFDQYLYSYYKADREAGR 306

Query: 297 ITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFR 356
           IT ++AQE++D + +KL  +   R     E F+G  ++    +GG   +GR    + SF 
Sbjct: 307 ITGEQAQEIIDCIFVKLNDINKCRDAASAEGFAGYGMFQNMIVGGQDSNGRDATNELSFM 366

Query: 357 FLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSI-DTSSLQYENDDLMRPDFNN--- 412
            L         P+P+++I      P +    AA+V+        Y ND+++ P   N   
Sbjct: 367 ILEASIH-TMLPQPSLSIRVWNGSPHDLLIKAAEVTRTGIGLPAYYNDEVIIPAMMNKGA 425

Query: 413 -----DDYAIACCVSPMIVGKQMQFF-GARANLAKTMLYAINGGVDEKLKMQVGPKSEPI 466
                 +Y I  CV P + GK   +   A  N+ + +    + G +      VG  +  +
Sbjct: 426 TLEEARNYNIIGCVEPQVPGKTDGWHDAAFFNMCRPLEMVFSSGYEN--GKLVGAPTGSV 483

Query: 467 KGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMAC- 525
           + +   ++   +     M++     + A N I   H K        ++ +  + R +   
Sbjct: 484 E-NFTTFEAFYDAYKTQMEYFISLLVNADNSIDIAHAKLCPLPFESSMVEDCIGRGLCVQ 542

Query: 526 -GIA----------GLSVAADSLSAIK---YAKVKPIRDEDGLAIDFEI 560
            G A          G++   DSL AIK   Y + K    E   A+    
Sbjct: 543 EGGAKYNFTGPQGFGIANMTDSLYAIKKLVYEEGKVSITELKEALLHNF 591



 Score =  262 bits (670), Expect = 3e-68,   Method: Composition-based stats.
 Identities = 67/192 (34%), Positives = 103/192 (53%), Gaps = 7/192 (3%)

Query: 564 YPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDG 623
            P++GN+   +D+ A ++   + K +QK    R  +    +  +++NV  G++TG TPDG
Sbjct: 679 LPKYGNDILEIDEFAREIAYTYTKPLQKYKNPRGGVFQAGLYPVSANVPLGEQTGATPDG 738

Query: 624 RRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRK 683
           R A  P   G  P  GRD KG  A+  SVA+L    A +G  Y     P+AL     + K
Sbjct: 739 RLANTPIADGVGPAPGRDTKGPTAAANSVARLDHMDATNGTLYNQKFHPSALQGRGGLEK 798

Query: 684 TNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSL 743
                L+  +F  +     G H+  NV++RE LLDA ++PE Y  L +RV+GY+  F +L
Sbjct: 799 --FVALIRAFFDQK-----GMHVQFNVVSRETLLDAQKHPENYKHLVVRVAGYSALFTTL 851

Query: 744 TKEQQQDVITRT 755
           ++  Q D+I RT
Sbjct: 852 SRSLQDDIINRT 863


>UniRef50_D1NB06 Formate C-acetyltransferase n=1 Tax=Victivallis vadensis ATCC
           BAA-548 RepID=D1NB06_9BACT
          Length = 712

 Score =  359 bits (921), Expect = 3e-97,   Method: Composition-based stats.
 Identities = 128/626 (20%), Positives = 221/626 (35%), Gaps = 81/626 (12%)

Query: 176 GRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLENGVNLEQTIRLRE-------EIAEQH 228
                D+R V   G   + +D+  +      D E         R+          +A++ 
Sbjct: 125 SHTSPDWRNVLKLGPAGI-RDRAEKALETAEDGEAREFFAAVARVYGAMCRYIVRLADEA 183

Query: 229 RALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYI 288
              G ++ +          P    Q+A+Q     +    + +     S G        + 
Sbjct: 184 DRRGAVR-VTGALRVIAERPPETLQQALQLALLYHH-TQELEGELVRSMGCFDRLFIGFY 241

Query: 289 ERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRT 348
            RDL AG++  ++A+E++     K                 G         GGM  DG  
Sbjct: 242 RRDLAAGRLNREQAKELLKFYWTKFFAQTQ-----------GKLWGKNFCFGGMDGDGSD 290

Query: 349 LVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAK-VSIDTSSLQYENDDLMR 407
              + +         +  + +P +++     LP      AA+ V    +++ + ND++ +
Sbjct: 291 ACNELTELGFEVYREL-RTVDPKLSLRVHGGLPEKVLLQAAECVCRGRTAVVFANDEIAK 349

Query: 408 PDFNND--------DYAIACCVSPMIVGKQMQFF-GARANLAKTMLYAINGGVDEKLKMQ 458
             F           D+    C  P ++GK++        NLAK +   +           
Sbjct: 350 EMFVRRGKLPEEIADFIPVGCYEPCVMGKELCCSMSTLFNLAKAVELLMEN--------- 400

Query: 459 VGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRD 518
                        ++ E++ER    +       +           + +    L    D  
Sbjct: 401 --------PAPPRDFGELLERYLGLVREKLDDALELTRRWELRWPEINPSPLLSGTMDSC 452

Query: 519 VIRT------------MACGIAGLSVAADSLSAIKYAKVKPIRDE-----DGLAIDFE-- 559
             +                  AGL  AADSL+A++    +  R         L  D+E  
Sbjct: 453 FEKGRDVSAAGTKYSSSGVMCAGLGSAADSLTALRILLFEERRCTWEELRATLKADWEGR 512

Query: 560 ------IEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVY 613
                 + G  P++GNN P  D LA  + +   ++I +    RD      + +I     Y
Sbjct: 513 EPLRLYVSGRLPKWGNNLPEPDALARKIADAVAERINRAPNARDGFFQTGMWSIDWAQRY 572

Query: 614 GKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPN 673
           G+ TG TPDGRRAG P          +D++G  A L S AKL  A   DG      + P+
Sbjct: 573 GRMTGATPDGRRAGEPLSKNLGAAIAKDRRGVAALLHSAAKLDQAEFPDGAVLDVMLHPS 632

Query: 674 ALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRV 733
            +   +  +   +A L+  YF       GG  +  N+++ + L  A   PEKY  + IRV
Sbjct: 633 MVKGKEGPKV--VADLVRTYFEA-----GGLFIQFNILDVDTLRRARREPEKYSSVQIRV 685

Query: 734 SGYAVRFNSLTKEQQQDVITRTFTQS 759
            G+ VRF  L    Q+  I    ++S
Sbjct: 686 CGWNVRFIDLDPAAQELFIQEAESKS 711


>UniRef50_A6CVH9 Formate C-acetyltransferase n=10 Tax=Bacteria RepID=A6CVH9_9VIBR
          Length = 763

 Score =  329 bits (844), Expect = 2e-88,   Method: Composition-based stats.
 Identities = 140/697 (20%), Positives = 257/697 (36%), Gaps = 92/697 (13%)

Query: 123 CKAYNRELDPM----IKKIFTEYRKTHNQGVFDVYT-PDILRCRKSGVLTGLPDAYGRGR 177
            +A+  EL P     +  +   +++   + ++   T  +    +   V            
Sbjct: 98  LEAFKTELSPEEHSRVDVLLDYWKERDTRSIYFRQTLTEATLGKFVDVNYPAIATARLSG 157

Query: 178 IIGDYRRVALYGIDYLMKDKLAQFTSLQADLENGV----------------NLEQTIRLR 221
           +  DY ++   GI  + +    +  S +A  +                    ++  I+L 
Sbjct: 158 MYLDYNKLIDNGIGGMRRLIGDKLDSARACHDTKAIALHESFLGCFDIVEKVIDHHIKLC 217

Query: 222 E---EIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFG 278
               E+        QM ++        +       + IQ ++   L +        ++FG
Sbjct: 218 AKELEVTTDLTRKHQMNDLIDALNAIRNDKPQTFLQGIQLSWLYSLCS------GVVNFG 271

Query: 279 RTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATES 338
           R   +L   +  DL+ G+ITE++A   +       R++   +T     +  G        
Sbjct: 272 RMDDYLGDLLVADLETGRITERQAINYIRSHY---RLIEARKTTVNGRVVVGG------- 321

Query: 339 IGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAK-VSIDTSS 397
           +G    +   +  K + + +          EP  T+   + +     + A + +    + 
Sbjct: 322 LGRRNPETADVYCKLAIQAVRE----NKDTEPQFTLRIYKGMNQGVYQDALEAIGEGLTY 377

Query: 398 LQYENDDLMRPDFNN---------DDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAIN 448
               NDD+  P   N           Y    C   ++ GK +       N+ K +  ++ 
Sbjct: 378 PILYNDDVNVPAVMNSMQISEQDAQHYVPFGCGEFVLSGKSVGTPNTCINILKILNISLT 437

Query: 449 GGVDEKLKM-QVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSY 507
           GG D      + G  S      V ++D+V++     +D+  +    A    + + ++   
Sbjct: 438 GGTDFWDGQNKSGGTSLLQPEQVTSFDDVIKNYKDLLDFYIELTSKAQAFSYQVMNQEVG 497

Query: 508 EASLMALHDRDVIR------------TMACGIAGLSVAADSLSAIK---YAKVKPIRDED 552
                 L D  + R                   G + A DSL+AIK   +   K    E 
Sbjct: 498 FLFTSILTDDCIGRSKALLDGGVYKLGGTNETYGNTNAYDSLAAIKKVIFEDKKYSYSEL 557

Query: 553 GLAIDFEIEG---------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQS 603
             A+    +G           P+FGN+D  VDD+AV++ E     I K    +  + +  
Sbjct: 558 IQALRVNFDGYDRMKYDLINAPKFGNDDAYVDDIAVEMHEYICNGI-KDSAAKVGMDSYL 616

Query: 604 VLTITS--NVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAK 661
           V+ I +  N  +G+ T  + DGR  G       NP  G D+ G  A L S+AKL  A   
Sbjct: 617 VVIINNQVNTEWGRATSASADGRHTGVYMSNANNPQSGADKNGPTAMLNSLAKLK-AEIH 675

Query: 662 DGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAME 721
            G         N        ++  +  L+DGYF      +GG  + V+V+ +  L DA  
Sbjct: 676 AGSVQNMKFSKNMYQN----KRMIVEALLDGYFE-----QGGPQIMVSVVGKGELEDAYH 726

Query: 722 NPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQ 758
           NPEKYP L +RV G++ +F +L K+ Q +++ RT   
Sbjct: 727 NPEKYPNLVVRVGGFSAKFVNLDKDVQLEILNRTLND 763


>UniRef50_Q39VF1 Formate C-acetyltransferase glycine radical:Pyruvate formate-lyase,
           PFL n=87 Tax=Bacteria RepID=Q39VF1_GEOMG
          Length = 862

 Score =  308 bits (789), Expect = 5e-82,   Method: Composition-based stats.
 Identities = 138/752 (18%), Positives = 254/752 (33%), Gaps = 97/752 (12%)

Query: 92  KQLEKIVGLQTEAPLKRALIPFGGIKMIEG-SCKAYNRELDPMIKKIFTEYRK-THNQGV 149
           +Q E I+G   E P    L P      ++      Y+ +      +I   ++K +     
Sbjct: 108 QQDEFIIGYHAEDPEMFPLYPELAYMAVQDYLMSDYSPQPKEEAAEINEYWKKYSMQAKG 167

Query: 150 FDVYT-PDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYG-----------IDYLMKD- 196
              +T  ++L+  +   +     A G   I   Y  V   G           I++  ++ 
Sbjct: 168 ERYFTQEELLQMYQVSTMEAPGFATGYNSISPPYETVLQDGLLKRIEMAHEKIEHAKREM 227

Query: 197 ---------------KLAQFTSLQADLENGVN-LEQTIRLREEIAEQHRA----LGQMKE 236
                          K+  + ++    E  +N   +  RL + +AE          ++ E
Sbjct: 228 QKIPWDATTGLDWIAKIDVWKAMIIADEAVINWARRHARLAKIVAENFETNPARKEELLE 287

Query: 237 MAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGK 296
           +A       + P    ++A Q  ++ YL        A+    +    L+ Y    +K   
Sbjct: 288 IAEISHRVPAEPCKGLKDAFQAKWYTYLICHAIDRYASGYAQKEDEMLEPYYNISVKEKS 347

Query: 297 ---ITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKN 353
              +T  +  EMV+   +K+      ++  Y E+F G       +IGG         +  
Sbjct: 348 FQPMTHTDVVEMVEMERLKISEHGAGKSRAYREIFPGSNDLFILTIGGTKPGYVDACSDM 407

Query: 354 SFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSIDT-SSLQYENDDLMRP---- 408
           +   L     +  + EP++   W        K+   +   D       ++D +       
Sbjct: 408 TDAILEGARNI-RTTEPSIVFRWHPVGREKTKRLVFECIRDGLGYPSIKHDVIGTEQLKY 466

Query: 409 ------------DFNNDDYAIACCVSPMIVG-----KQMQFFGARANLAKTMLYAINGGV 451
                       D     + +  C+SP + G     K     G     AK M   +  G 
Sbjct: 467 YSQFSKNNNGATDDEAHYWGLVLCMSPGVCGRRKTHKTRSEGGGSIFPAKMMEIVLADGF 526

Query: 452 D-EKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEAS 510
           D     MQ+GP +         ++++ E       +   + I A +I+ Y   K+     
Sbjct: 527 DWSYSGMQLGPHTGDPTT-FKTFEQLWEAFRSQYAYATSKVIRAKDIMRYYESKFLQMPF 585

Query: 511 LMALHDRDVIRTMAC-----GIAGL------SVAADSLSAIK---YAKVKPIRDEDGLAI 556
           + ++ D  +   +          G        VAA+SL AIK   Y + K    +   A+
Sbjct: 586 VSSIDDGCMELGIDSMELSEQPNGWHNPITTVVAANSLVAIKKLIYDEKKYTMAQLVTAL 645

Query: 557 DFEIEG---------EYPQFGNNDPRVDDLAVDLVERFMK-KIQKLHTYRDAIPTQSVLT 606
                G           P++GN+D   D +     E  +  ++ K+  Y           
Sbjct: 646 RANWHGYEDMRQDFLNAPKWGNDDEYADTIIKKFYEDIIGGEMAKITNYSGGPVLPVGQA 705

Query: 607 ITSNVVYGKKTGNTPDGRRAGAPFGPG-ANPMHGRDQKGAVASLTSVAKLPFAYAKDGIS 665
           +   +  G +TG TPDGR  G     G  +P  G D+KG  A L SV+K+      +   
Sbjct: 706 VGLYMEIGSRTGPTPDGRFGGDAGDDGGISPYMGTDKKGPTAVLKSVSKVQKNQKAN--L 763

Query: 666 YTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEK 725
               +    +             +   Y      +    H+  N ++   +  A + PEK
Sbjct: 764 LNQRLSVPIMRSVHGF------TIWKSYMDAWEKLN-IDHVQFNCVSTAEMKAAQKEPEK 816

Query: 726 YPQLTIRVSGYAVRFNSLTKEQQQDVITRTFT 757
           +  L +RVSG++ RF  +    Q  +I R   
Sbjct: 817 HQDLIVRVSGFSARFVDIPTYGQNTIIARNEQ 848


>UniRef50_A7VW43 Putative uncharacterized protein n=1 Tax=Clostridium leptum DSM 753
           RepID=A7VW43_9CLOT
          Length = 737

 Score =  308 bits (789), Expect = 6e-82,   Method: Composition-based stats.
 Identities = 108/598 (18%), Positives = 218/598 (36%), Gaps = 70/598 (11%)

Query: 194 MKDKLAQFTSLQ-ADLENGVNLEQTIRLREEI---AEQHRALGQMKEMAAKYGYDISGPA 249
            K+K   + + +   L     +++ I   EE+    ++      ++EM A     IS   
Sbjct: 168 DKEKQEFYDAEEKVVLAIQKWIQKHIDRIEELLKTEDRPEIRATLEEMLACNKNVISKKP 227

Query: 250 TNAQEAIQWT-YFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDH 308
               EA Q+  +F  ++ +  ++GA          L  + ++D+++G I + +A+ ++  
Sbjct: 228 ETFLEACQYLAWFATVSRIYDRDGAGCW---LDQLLYPFYKKDMESGLIDKDKARFILAD 284

Query: 309 LVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSP 368
           L++          P Y +            +GG  L+G  +  + S+  L   + +  S 
Sbjct: 285 LLI--------IDPHYYQ------------LGGCDLEGNDMTNELSWLILEAAHELNTSA 324

Query: 369 EPNMTILWSEKLPLNFKKFAAKVSI----------DTSSLQYENDDLMRPDFNNDDYAIA 418
             N+T+   + +   F K A                   +     +    + +  +    
Sbjct: 325 --NLTVRVHDNMDPAFFKKAVSYVFNDRNAWPRFSGHKGMMNYAKNQGVSEKDALERQAV 382

Query: 419 CCVSPMIVGKQMQFFGA-RANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVM 477
            C    + GK+       + N  K    A    +          K +        YD   
Sbjct: 383 GCGWSAVPGKEFCMNDVIKINCVKVFEVAFQEMMLAYHDAAPTDKEKYAPSLERLYDIYR 442

Query: 478 ERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDV-------IRTMACGIAGL 530
             +   +  +A          H    +      +    +          I T+ C   GL
Sbjct: 443 AHLKRAVKVIADCVEFYNQYQHITMPELVMNLQMYHTLEEGKNISQCAEIYTLCCDGVGL 502

Query: 531 SVAADSLSAIKYA---KVKPIRDEDGLAIDFEIEGEYP---------QFGNNDPRV-DDL 577
              ADS +AI+     + K   +E    +     G+           ++      + D  
Sbjct: 503 GTLADSFAAIEQRIVREKKLTFEELEETLRNNFAGDERTRLMLSQSERYCQGGDSLGDQW 562

Query: 578 AVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPM 637
           A  L   F + ++               + +  + +G++ G TP+GR+AGA    GANP 
Sbjct: 563 AQRLTRDFAEIVKAQPVAGGKQLVPGWFSWSKTIHFGRQVGATPNGRKAGASVTHGANPT 622

Query: 638 HGRDQKG-AVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHH 696
            G  + G A A  T +A     Y  +         P      +E     +A L+  +   
Sbjct: 623 PGFRKDGAATAQATGIALCQPGY-GNTAPLQIEFDPKL--SAEEGGIDRVAKLLKTHIDM 679

Query: 697 EASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITR 754
                GG  +NVNV+++++L++A ++P+ +P+L +RV+G+   F +L+++ +Q V+ R
Sbjct: 680 -----GGTLINVNVLDKDVLMEAHKDPKSHPELVVRVTGFTAYFCTLSEDFRQLVVDR 732


>UniRef50_O26446 Formate acetyltransferase 2 n=1 Tax=Methanothermobacter
           thermautotrophicus str. Delta H RepID=O26446_METTH
          Length = 642

 Score =  295 bits (755), Expect = 4e-78,   Method: Composition-based stats.
 Identities = 123/661 (18%), Positives = 230/661 (34%), Gaps = 113/661 (17%)

Query: 134 IKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGR-GRIIGDYRRVALYGIDY 192
           ++K+  + R   N G    Y+ D      +G+     + Y R G +  DY  +   G++ 
Sbjct: 53  LEKVCRDSRIHFNPGDRFFYSID------TGIHVLETEGYRRLGNLTPDYGLLVERGLEG 106

Query: 193 LMKDKLAQFTSLQADLENGVNLEQTIRLREEIAEQHRALGQMKEMAAKYGYDISGPATNA 252
           + ++ +        D+     L       E  AE         E+A K       PA   
Sbjct: 107 I-EEMIEDEPGGYPDILRRA-LGAVKLYLERCAEHSP------EIADKLRRVPLKPAETL 158

Query: 253 QEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMK 312
            EA+Q   F             +  GR  + L  Y E          +E++E++   ++ 
Sbjct: 159 GEALQSILFMNSLIWM-YGHPLIGLGRLDSILKEYHE--------DPEESRELIRDFILS 209

Query: 313 LRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNM 372
           +      ++                 +GG            +  FL  +  +   P+P +
Sbjct: 210 VSSCYEFKSNVLPG-----DTGQVIVLGGE-------YNDLTRIFLEVMLELRI-PDPKV 256

Query: 373 TILWSEKLPLNFKKFAAKVSI-DTSSLQYENDDLMRPDF-------NNDDYAIACCVSPM 424
            +  + + P +  + + +          + NDD++           +  +YA + C  P+
Sbjct: 257 VLRVNSRTPDDVWELSYRCLREGLGYPLFSNDDVIVDALSQYYSRSDALEYATSACWEPL 316

Query: 425 IVGKQ-MQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHF 483
           I G+   Q   A  NL + +  A++G                 +G+   + E++ER    
Sbjct: 317 IPGRSSDQNNLANLNLLEPLEDALHG----------------FRGE---FSELLERYRQE 357

Query: 484 MDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRT------------MACGIAGLS 531
           +           +++  +    +  + L++L   D IR                   G+ 
Sbjct: 358 LHRYID------DVMENVESVRNEPSPLLSLLFPDCIRNSRDICDGAGYSINGVLTVGMG 411

Query: 532 VAADSLSAIKYAKVKPIRD-----EDGLAIDFE--------IEGEYPQFGNNDPRVDDLA 578
              +SL  I+              ED L  DF         +E   P +G ++  V +L 
Sbjct: 412 NLINSLLNIRRLCYDEKTMNIAEVEDVLRDDFRSAEALRVGLELISPGYGMDEDEVVELT 471

Query: 579 VDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMH 638
             +++    K+   + +         L+    +  G+ TG + DGR AG P G   +P+ 
Sbjct: 472 NTIIQMLHDKLGGRYKFG--------LSSPVYITLGESTGASFDGRHAGEPLGVHISPLK 523

Query: 639 GRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEA 698
             D       L   A L +  A +G      +    L +           L+        
Sbjct: 524 FTDGMSYTEVLNFAAALDYLKAFNGGVVDIMVDRPFLDRAGNE----FMALIRT-----G 574

Query: 699 SIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQ 758
              G   L VNV++ E+LL A +NPE YP L +RV G++  F  L +E ++ ++ R    
Sbjct: 575 LRRGVMQLQVNVLDPEVLLRARDNPELYPDLIVRVWGFSAYFRDLPEEYRELIVRRALEY 634

Query: 759 S 759
           S
Sbjct: 635 S 635


>UniRef50_C0A3H6 Formate C-acetyltransferase n=1 Tax=Opitutaceae bacterium TAV2
           RepID=C0A3H6_9BACT
          Length = 765

 Score =  295 bits (755), Expect = 5e-78,   Method: Composition-based stats.
 Identities = 119/603 (19%), Positives = 221/603 (36%), Gaps = 102/603 (16%)

Query: 201 FTSLQADLENGVNLEQTIRLREEIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWT- 259
                A+++  +  E   RLRE           ++EM A   + + G     +EA QW  
Sbjct: 217 IRRTIAEVDRQLATEADPRLREN----------LREMKAVNEWVVEGAPRTLREACQWLA 266

Query: 260 YFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFL 319
           +F       ++ GA    G+    L  Y ERD  AG I ++EA   +  L++        
Sbjct: 267 WFVLAKRTYNRCGAG---GQLDELLRPYYERDAAAGLIDDEEAAFTIACLLL-------- 315

Query: 320 RTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEK 379
              +Y +            + G G DGR + ++ S   L+    M      N+TI   + 
Sbjct: 316 VDAQYYQ------------LAGPGPDGRDMTSRISHIILDAAELMDG--PCNLTIRVHDD 361

Query: 380 LPLNFKKFAAKVSI--DTSSLQYENDDLMRPDFNNDDYA--------IACCVSPMIVGKQ 429
           L     +    +         ++  D  +   F    Y+           C    + G +
Sbjct: 362 LDPELFRRGVYLLFHHKKGWPRFSGDKALVAGFMRAGYSEELARQRIAVGCNWMSLPGLE 421

Query: 430 MQFFGA-RANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLA 488
                  + NLAK    A           +    +          + + E     +    
Sbjct: 422 YTLNDVVKVNLAKVFEVA----------WKEMFAAANDGTAAPGLERLWEIYLAHLRVAV 471

Query: 489 KQYITALN--IIHYMHDK----------YSYEASLMALHDRDVIRTMACGIAGLSVAADS 536
           ++     +  + H  H++             E  L           +A   AG++V ADS
Sbjct: 472 EKTADGNHFHMCHQTHNEPELVTNLLCHGPLEKGLDMAAGGARYCNLAIDGAGIAVVADS 531

Query: 537 LSAIKYAKVKPIRDEDGLAI---DFEIEGEYPQFG--------NNDPRVDDLAVDLVERF 585
            +A++    + + DE  L     ++ IE  +P            +  R      +  ER+
Sbjct: 532 FAALE----QRVADEGCLTWAEVNWHIEKNFPDIEGERVRLMLQSSERYGQATGNRAERW 587

Query: 586 MKKIQKLHT---------YRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANP 636
             +I    +         Y D      + +  + + +G+    TP+GRRAG P   GANP
Sbjct: 588 AVRITGTWSGMVRDQNRRYPDYNFIPGLFSWANTIEFGEAVSATPNGRRAGQPINHGANP 647

Query: 637 MHGRDQKGA-VASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFH 695
           + G  + GA  A + ++A +   Y  +       + P+     + + K  +  L+   F 
Sbjct: 648 LPGFRKDGAVTALVNAIAAVQPGY-GNTAPVQLELDPSIAESPEAIEK--ITALIKTMFD 704

Query: 696 HEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRT 755
                +G   LN+N+++ E +L+A ++P K+P L +RV+G+   F  L+ + +Q V+ R 
Sbjct: 705 -----QGCTLLNINLIDEERVLEAHKDPSKFPDLIVRVTGFTSYFAMLSPQFRQLVVDRI 759

Query: 756 FTQ 758
            ++
Sbjct: 760 LSR 762


>UniRef50_C6IIV1 Formate acetyltransferase 2 n=3 Tax=Bacteria RepID=C6IIV1_9BACE
          Length = 714

 Score =  295 bits (754), Expect = 5e-78,   Method: Composition-based stats.
 Identities = 135/694 (19%), Positives = 252/694 (36%), Gaps = 109/694 (15%)

Query: 119 IEGSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILR--CRKSGVLTGLPDAYGRG 176
           I+       R +  M K    ++           Y+ D L+   +K  ++ G+ D     
Sbjct: 76  IDADDAFAGRWMYFMSKMRPNKWN--------PDYSYDFLKENIKKYDLICGIGDDA--- 124

Query: 177 RIIGDYRRVALYGIDYLMKD---------KLAQFTSLQADLENGVNLEQTIRLREEIAEQ 227
               DY      G + L+K             Q       L    +++  I+   + A +
Sbjct: 125 HFAPDYEIGVKLGWNGLIKKIEHYQSMHHSEEQQHFYSLHLRVIRSVQGWIQRHIDQAYR 184

Query: 228 HRALGQ-------MKEMAAKYGYDISGPATNAQEAIQWTYFGYLA-AVKSQNGAAMSFGR 279
             A          + E+A      I+   T  +EA QW  + +LA    +++GA    G+
Sbjct: 185 MAASATDDCSKNNLLEIAKVNESIINDAPTTLREACQWIIWYHLASRTYNRDGAG---GQ 241

Query: 280 TSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESI 339
             T L  + E+DL  G+I ++ A   +   ++                   DP++    +
Sbjct: 242 IDTLLAPFYEKDLAEGRIDKETAVYYLACFLL------------------NDPVY--WQL 281

Query: 340 GGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAK--VSIDTSS 397
           GG    G+   +  SF  L     +  S   N+T+   + L  +  + + +  V      
Sbjct: 282 GGPDESGKDQTSPLSFLILEAADKINTSL--NLTVRVFDGLNKDLFRKSVEYLVKNKNGW 339

Query: 398 LQYENDDLMRPDFNNDDYAI--------ACCVSPMIVGKQMQFFG-ARANLAKTMLY--- 445
            ++  D  +   F  + ++           C    + G +       + N+AK       
Sbjct: 340 PRFSGDKALVEGFMKNGFSAQLARRRIAVGCNWMSLPGLEYTMNDLVKINMAKVFEVSYT 399

Query: 446 -AINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDK 504
             +N   D          +E +   V    + +     F  +          ++  +   
Sbjct: 400 EMMNEQKDHSTSRLWMLFNEHLAKAVQTSADGIRHHLKFQKY------NEPELLLNLLSH 453

Query: 505 YSYEASLMALHDRDVIRTMACGIAGLSVAADSLSAIKYAKVKPIRDEDGLAIDFEIEGEY 564
              E              +A   AGL+  ADS +A++    + I  E+ L+ +   E   
Sbjct: 454 GPLEKGKDVSDGGAEYYNLAIDGAGLATVADSFAALE----QRIELENKLSWNTLTEYLR 509

Query: 565 PQF-GNNDPRVDDL---------AVDLVERFMKKIQKLHT---------YRDAIPTQSVL 605
             F G+   R+  L         A  L E++  +I++  T          +  I      
Sbjct: 510 NNFSGDGGCRIRHLLKNSEKYGAAESLGEKWAIRIKETFTELVRLQSEPDKRRIFIPGFF 569

Query: 606 TITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTS-VAKLPFAYAKDGI 664
           +  + V +G+  G TPDGR A  P   GANP  G  + GA  SL + +AK+   Y  +  
Sbjct: 570 SWANTVGFGQSVGATPDGRLAQTPISHGANPTPGFVKDGASLSLATIIAKIQPGY-GNTA 628

Query: 665 SYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPE 724
              + + P     D+      +  ++  +F       GG  +NVN+MN++ +L A ++P 
Sbjct: 629 PMQWELDPTFANMDN---IELIMSIIRAHFDL-----GGTLINVNIMNKDTVLAAHKDPA 680

Query: 725 KYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQ 758
            YP+L +RV+G+   F+ L+ + +Q V+ R    
Sbjct: 681 GYPELVVRVTGFTAYFSMLSPQFRQLVVDRILES 714


>UniRef50_D1N9D9 Formate C-acetyltransferase n=1 Tax=Victivallis vadensis ATCC
           BAA-548 RepID=D1N9D9_9BACT
          Length = 748

 Score =  292 bits (747), Expect = 4e-77,   Method: Composition-based stats.
 Identities = 121/689 (17%), Positives = 226/689 (32%), Gaps = 102/689 (14%)

Query: 147 QGVFDVYTPDILRCRKSGVLTGLPDA------YGRGRIIG---------DY-------RR 184
            G  ++ +   L  R   + +  P+       Y  G +IG         DY         
Sbjct: 82  DGCVNLSSGGWLYLRNVALYSDSPEKAADYRRYCYGDLIGLHLSYGPYYDYDHHCFPFSN 141

Query: 185 VALYGIDYLMKDKLAQFTSLQADLENGVNLEQTIR--------------------LREEI 224
           +   G+  ++K +L +  +   + E     E   R                       E 
Sbjct: 142 MLELGLSGILK-RLEEGHARNTEPEKAEFYEAARRGILAVRKIAEKFAAAAEEKLASAES 200

Query: 225 AEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFL 284
            E+ + L +++  A         P     E ++  +F +              G     L
Sbjct: 201 PEERKNLERIRTAA---RRIPWNPPQTFYEGLECLWFFHELGSVLDGIGMSVLGSPDRQL 257

Query: 285 DVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGL 344
                RD++  ++TE EA E++  L M     +       +  F+      T  +GG+  
Sbjct: 258 IRLYRRDIQEKRLTEAEAYELI-CLYMLQTDSKLDFDRPIEGQFNAGEQGDTLILGGLDE 316

Query: 345 DGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAK-VSIDTSSLQYEND 403
            G  +  + +F FL     +     P + I +S + P    + AAK    D + L + ND
Sbjct: 317 SGNDVTNELTFLFLKAHREL-KLTYPKIHIRFSSRTPAVLFQEAAKDFLADRNVLSFLND 375

Query: 404 DLMRPDFN--------NDDYAIACCVSPMIVGKQM-QFFGARANLAKTMLYAINGGVDEK 454
           D++ P              Y    C   ++ G +  Q   +  +L K +  +I+   + +
Sbjct: 376 DIVIPSQIMAGKTPESAARYVAGGCWENILEGYEHSQGANSYFSLGKCVDLSIHE--ENE 433

Query: 455 LKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMAL 514
            +  +      + G   +++ V   +   +     Q  +       +  + +      A 
Sbjct: 434 DEKSLELPFRKLDG-ATSFEGVYSIVMDNIKLALHQLFSIQQKYGALWTQVNPCPFFSAC 492

Query: 515 HDRD------------VIRTMACGIAGLSVAADSLSAIKYAKV---------------KP 547
            +                        G++V  DSL A+K                     
Sbjct: 493 LNGCAESGRDYSAGGACYSPHGIPFTGVAVLVDSLLALKTICFGENPVPLPRLLAVIRND 552

Query: 548 IRDEDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTI 607
            RD + L          P  G+       L   ++      +         I    + + 
Sbjct: 553 WRDAEALRCRAM---ASPHLGDGKGEAARLTARILNDLADYVAGFRNELGGIYQCGLYSY 609

Query: 608 TSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYT 667
              + + K T  TPDGRRAG     G  P             +  A LP          T
Sbjct: 610 RDIIDWAKVTRATPDGRRAGDFLSQGLTPAR-THADAVTQVFSDTASLPLLRFPANSVLT 668

Query: 668 FSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYP 727
            S+  N L +           L+ G+      + G   L +N ++RE L DA +NP+ + 
Sbjct: 669 LSLSKNGLTE----------ALLSGFLKAWVLVRGSGMLQLNCISREELEDAQKNPQNHA 718

Query: 728 QLTIRVSGYAVRFNSLTKEQQQDVITRTF 756
            L +R+ GY+ +F +L++E+Q++ I+R  
Sbjct: 719 SLIVRLYGYSAKFITLSEEKQREFISRNI 747


>UniRef50_C5V5J7 Formate C-acetyltransferase n=1 Tax=Gallionella ferruginea ES-2
           RepID=C5V5J7_9PROT
          Length = 962

 Score =  280 bits (716), Expect = 2e-73,   Method: Composition-based stats.
 Identities = 121/783 (15%), Positives = 222/783 (28%), Gaps = 172/783 (21%)

Query: 122 SCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGD 181
             +     +DP +KK+  E             TP      +         +      + D
Sbjct: 187 MDEVNGDSIDPALKKMAGE-------------TPKCQELMERVAFYLSDKSTCVSHTVPD 233

Query: 182 YRRVALYGIDYLMKDKLAQFTSLQADLENGVNL------EQTIRLREEIAEQHRALGQMK 235
           + R+  YG+D L            ++             E  +     +AE   A G   
Sbjct: 234 WDRLLKYGLDGLAAQMRFDLAVANSEPARQFLAGVIDTFEGAMTYANHLAEAAEAAGN-S 292

Query: 236 EMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIER----- 290
           E+A       + PA    EA+   +  Y   ++      +S GR    L+ Y  +     
Sbjct: 293 ELARICRKVPAQPADTLHEALSAIWICYHLLLQENTNFGLSLGRLDQLLNPYYFKEWQKL 352

Query: 291 --DLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMG-LDGR 347
             D      T   A E++ H  ++      L T   + LF+G       ++GG    +G+
Sbjct: 353 GSDEARASYTR-HAVELICHFFLRCSDHVPLSTSGSETLFAGSGSNQALTVGGTRYENGQ 411

Query: 348 --TLVTKNSFRFLNTLYTMGPSPEPNMTILWSEK---------------LPLNFKKFAAK 390
               V   ++  L     +    +PN+   +                  +    K+    
Sbjct: 412 VVDAVNDMTYIILKATELLSIR-DPNVHARYHADVHRRDADGNSLSRDAMDDYLKRICQV 470

Query: 391 VSIDTSSLQYENDDLMRPDFNND-----------------DYAIACCVSPMIVGKQMQFF 433
                ++     D  +                        DYA   C+     GK     
Sbjct: 471 NIATRATPALHGDIPVIRSMAAYYADHKGVSDEEAMQDACDYASIGCIEQNAPGKHYGNS 530

Query: 434 GAR-ANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDV----------LNYDEVMERMDH 482
           G+    L   +  AI GG         G   +   G               +E +     
Sbjct: 531 GSTLLVLPAVLELAIFGGKHRSDGT-GGTDPDLFNGQPRYTSVPLLGMTCMEEFVSAFGF 589

Query: 483 FMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDV-----------------IRTMAC 525
            ++ +AK  +   N +  +  K      L  L    V                  +  + 
Sbjct: 590 QLNEMAKHAVQNNNYLGRVMAKERASPFLSGLFTGPVNLPGEQGAKFRDVAAGGAKYNSA 649

Query: 526 GIA--GLSVAADSLSAIKYAKV--KPIRDEDGLAIDFEIE--------GEYP-------- 565
           G+A  GL+   D+   +       K    E   A+  +           ++P        
Sbjct: 650 GVAIIGLADVIDTFCILDELVFSGKVSAAELLSAMGSDFSVAKHASEQHDWPHYLEKMRR 709

Query: 566 -----------------------------QFG--------NNDPRVDDLAVDLVERFMKK 588
                                         +G         ++      +  L     + 
Sbjct: 710 WLHPDATVPLPALSAERLAEICTAIKHTAHYGAGVAQNGIFDNSLAVTYSRRLTRMIHEV 769

Query: 589 IQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVAS 648
                T+R         ++T++  +G  T  TP+ RRAG  F  G  P  G  ++     
Sbjct: 770 FYAYRTHRGGRYLTGYWSMTNHAGFGMLTQATPNLRRAGQAFASGITPCPGIVKRDGTPV 829

Query: 649 -----LTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGG 703
                + SVA +     K+G +Y  S+       +        A  M  +  +      G
Sbjct: 830 MALDHMLSVAAVDSDAVKNGYTYNLSLTTRG-AAERSADIELFARYMRAFTDNN-----G 883

Query: 704 QHLNVNVMNREMLLDAMENP-----------EKYPQLTIRVSGYAVRFNSLTKEQQQDVI 752
             + + V +   L+ A +               Y  L IRV+GY+  F +L+ + + ++I
Sbjct: 884 VLVQLCVSSIADLVAADKAAAMEGAGAFEALAPYKDLMIRVAGYSAYFVTLSAQMRTEII 943

Query: 753 TRT 755
            R 
Sbjct: 944 ARA 946


>UniRef50_C7XCZ5 Formate acetyltransferase 2 n=2 Tax=Bacteria RepID=C7XCZ5_9PORP
          Length = 670

 Score =  275 bits (703), Expect = 5e-72,   Method: Composition-based stats.
 Identities = 110/615 (17%), Positives = 218/615 (35%), Gaps = 81/615 (13%)

Query: 178 IIGDYRRVALYGIDYLMKDKLAQFTSLQADLENGVNLEQTIR-LREEIAEQHRALGQMKE 236
           I  DY  +    +  +M+    +       +     + + I      I+EQ     + + 
Sbjct: 94  ITPDYALIINSDLREIMRSLPERSGDNSDFIGTLHIVTKAIEDKARAISEQRYEDVRYEA 153

Query: 237 MAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGK 296
           MA +    +     +  EAIQ   F      +  +   +  GR    L  Y ++D++A +
Sbjct: 154 MAKRLPDLLYRDCQSLVEAIQKVLFYNGLLWQVGHRH-VGLGRMDLVLYPYYKKDVEANR 212

Query: 297 ITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFR 356
           +  ++A+ ++  + + L     +++                 +GG+  +G+    + +  
Sbjct: 213 LNYEQAKGLLKEMCLLLGKDSPMKSLNLIG-----DSGQYIILGGVDKNGKNTDNELTRM 267

Query: 357 FLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVS-IDTSSLQYEND-----DLMRPDF 410
           FL     +   P+P +    +E+ P++  K + +       S  + N+     ++++  +
Sbjct: 268 FLELFEELRI-PDPKLIFRVNEETPMDTWKRSIRCLANGCGSPLFMNETLIMENMVKFGY 326

Query: 411 NNDDYAIAC---CVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIK 467
            N+D        C  P+I+GK         ++                      K+    
Sbjct: 327 RNEDVWNVGTSACWEPLIIGKSSDQNNPFISILAC---------------NALKKALTEM 371

Query: 468 GDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTM---- 523
            D L+Y  +++ +   +    +  +        +   Y Y   +   ++  +        
Sbjct: 372 EDELDYGGLLQLVKRNLAEETRSVV--------VDKDYDYSPIMSLFNESCIRSGKDFAH 423

Query: 524 --------ACGIAGLSVAADSLSAIKYAKVKPIRDEDG---LAIDFEIEGEYP------- 565
                      + GL    +SL  IK    +      G     +  + E           
Sbjct: 424 QGSDYMYQGAQLLGLPNLVNSLLNIKKYVYEQGLVSLGICREIVQTDYENHLDIKQLFKS 483

Query: 566 ----QFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTP 621
               +FG  D  V  L+ +L+    + I KL    +    +  L+  S +  GK    T 
Sbjct: 484 ANDKKFGLCDEYVLRLSQELIGTVSETIGKLTA--NGYNVKFGLSSPSYISRGKVASATL 541

Query: 622 DGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFA-YAKDGISYTFSIVPNALGKDDE 680
           DGR AG PF    +P+           L   + L +     +G    + I P  L   D 
Sbjct: 542 DGRNAGEPFAVHISPLSSTID--IAEVLDFASSLSYPVNCLNGNVVDYVIPPVYLNNSD- 598

Query: 681 VRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRF 740
                L  ++   F      +G   L +NV +R  L+DA  +PEKYP L +RV G++  F
Sbjct: 599 ----KLVPILRDAFK-----KGLYQLQLNVYDRATLIDAKLHPEKYPTLVVRVWGFSAYF 649

Query: 741 NSLTKEQQQDVITRT 755
           N L +E + ++I R 
Sbjct: 650 NDLPEEYKDNLIARA 664


>UniRef50_C7ILA9 Formate C-acetyltransferase n=1 Tax=Clostridium papyrosolvens DSM
           2782 RepID=C7ILA9_9CLOT
          Length = 866

 Score =  265 bits (677), Expect = 5e-69,   Method: Composition-based stats.
 Identities = 130/782 (16%), Positives = 244/782 (31%), Gaps = 183/782 (23%)

Query: 148 GVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQAD 207
            VF  Y  +    +++G  T   +    G    +Y  +   G++ ++K+   +   L++ 
Sbjct: 97  KVFPNYLTE--NEQRAGAFTNKTELSLLGHNSVNYDNLLDKGLNAIIKEAEEKLEDLKSV 154

Query: 208 ---LENGVN-------------------LEQTIRLREEIAEQHRAL---------GQMKE 236
               E G +                   +E +++  +   E  + L          ++ E
Sbjct: 155 GEMFETGDDKRKNAIDFYNAVIISCSSVIEYSLKFADLAGEMAKGLTDPKDGARKKELLE 214

Query: 237 MAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGK 296
           +                EA+Q  +  + A   S N   +S GR    L  Y+++D    K
Sbjct: 215 IERICRKVPMEKPDTFHEALQSIFTFHTALHASLN--YLSLGRLDQVLVKYLDKD----K 268

Query: 297 ITEQE----AQEMVDHLVMKLRMVRFLRT------------------PEYDELFSGDPIW 334
           IT+++      E+ +  ++K      + T                  P Y +  +G   +
Sbjct: 269 ITDEDYLKKCTELFECFIIKAAWRLNMTTEYLVEQDHMDHNAALGVHPYYIDQRAGVNNF 328

Query: 335 -ATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSI 393
                +GG   DG+  V K ++  LN    +  S  P +      +     KK  A++  
Sbjct: 329 LQNIIVGGKTPDGKDAVNKMTYIILNAFENVNLST-PGIYARLHSQSDDKLKKRVAEMLS 387

Query: 394 DT-SSLQYENDDLMRPDFNN----------------------------DDYAIACCVSPM 424
            T +     NDD++ P   N                            +DY +  C  P+
Sbjct: 388 KTKNLPGILNDDVLIPAMFNGLRENDVDLDITKVKSFSGKEAEYMRLANDYCVDGCWEPI 447

Query: 425 IVGKQMQFFGARANLAKTMLYAINGGV--DEKLKMQVGPKSEPIKGDVLNYDEVMERMDH 482
           + G     FG   N    +   +N G   D    M  G K   I     +Y+   +  + 
Sbjct: 448 LNGNSDWTFG-MLNGMTILQCTLNRGATLDTNPGMLRGGKMSFISDVPTDYNSFKKIFEK 506

Query: 483 FMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRT------------MACGIAGL 530
            M +   Q    L   + + +  +      ++    + +                 + G+
Sbjct: 507 QMQFFIDQSTFGLYEYYMLDEFVNPSPLFSSVFGGCMQQGRDKSWGGAEYNLGGTILIGI 566

Query: 531 SVAADSLSAIK---YAKVKPIRDE--DGLAIDF-------------------EIEGEYPQ 566
               ++L+AIK   + + K    E  D +  +F                   +     P+
Sbjct: 567 PDMINTLAAIKKWVFDEKKYSLQEVLDAMRSNFVSPAKENVILQKRYDSIRIDFNTNTPK 626

Query: 567 FGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAI--------------------------- 599
           FG ND  + ++   ++E +   I+      D +                           
Sbjct: 627 FGENDKEISEIGSYIIETYCNSIKSSKKLADKVFLIPLREFSEKEKAEILRLRKICGYFG 686

Query: 600 --------------PTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGA 645
                          T    T     + G     +PD R +  P  P  +P  G  QK  
Sbjct: 687 NSLQNKFGKDFNIRFTAGCGTFEQYPLQGLGIVASPD-RNSNDPLAPNLSPYPGTVQK-P 744

Query: 646 VA-SLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNL-----AGLMDGYFHHEAS 699
            A  L S+  L       G      I   A   +      N        +M      +  
Sbjct: 745 TAHILESLKALNLNKLAAGAITDLCIDYKANNVEHIAGIINKFIESDGNMMTLAIGDKEE 804

Query: 700 IEGGQHLNV---NVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTF 756
            +    L+V   N  ++E    A E  E+Y  + +RV G+   F S++ +QQ+  I R  
Sbjct: 805 YQKIYELSVTASNSSDKEASKAAYEKLEQYKHVNVRVGGWQAPFVSMSLDQQKSYILRIL 864

Query: 757 TQ 758
            +
Sbjct: 865 EE 866


>UniRef50_B9M4R7 Formate C-acetyltransferase n=2 Tax=Bacteria RepID=B9M4R7_GEOSF
          Length = 853

 Score =  254 bits (650), Expect = 7e-66,   Method: Composition-based stats.
 Identities = 119/756 (15%), Positives = 221/756 (29%), Gaps = 158/756 (20%)

Query: 148 GVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKD---KLAQFTSL 204
            VF  Y  +    +++  +T   +    G    DY R+  YGI  +++    K A+  + 
Sbjct: 98  KVFPNYLTE--DEKRAARITNRTELSLLGHNTADYDRLVRYGIRGILETCESKSAEIKAK 155

Query: 205 QADLEN-----------GVNLEQTIRLREEIAE----------QHRALGQMKEMAAKYGY 243
           Q   E+            +  E  +      A+            R   ++ E+      
Sbjct: 156 QPLTEDDQNKLDFYRAVRIASEAVVEYAGRFADLARDKGRTESDLRRRAELAEIERICRK 215

Query: 244 DISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQ 303
               PA    EA+Q  +F + A   S N   +S GR    L  Y+   ++ G     +  
Sbjct: 216 VPLEPADTFHEALQSIWFVHTALHASMNL--ISLGRLDQVLAPYLASTVEKGVYDPAKGV 273

Query: 304 EMVDHLVMKL-----RMVRFLRTPEYDELFSG--------------DPIWATESIGGMGL 344
           E+ +  ++K          +L   ++ +  +               +       IGG+  
Sbjct: 274 ELFECFLIKAAWRLNYTTEYLVQQDHMDYNAALGVNPYYLDQRAGANNFLQNVIIGGLKP 333

Query: 345 DGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSS-LQYEND 403
           DG       +F  L     +   P P + +      P N K   A+   +T +     ND
Sbjct: 334 DGSDATNDCTFVILRAYRNVN-LPTPGIYVRMGSSSPENLKFAVAESLHETGNNPSILND 392

Query: 404 DLMRPDFNN---------------------DDYAIACCVSPMIVGKQMQFFGARANLAKT 442
           D++ P                         +DY +  C  P++ GK    FG   N    
Sbjct: 393 DVLIPALYRAFCEGEDPTDRARLAELKAVVNDYCVDGCWEPILNGKSDWTFG-MINGMTI 451

Query: 443 MLYAINGGV--DEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHY 500
           +  ++N G   D       G K     G++ +Y  + E +   + +   Q    L   + 
Sbjct: 452 LECSLNKGATLDNNPGTLRGGKLSYSSGEIASYGALRESLRGHLQFFVDQSAFGLYKYYM 511

Query: 501 MHDKYSYEASLMALHDRDVIRTMACGIAG--------LSVAADSLSAIKYAKVKPIRDED 552
             +         A     + R       G        +     ++     A  K + DE 
Sbjct: 512 TDEYVVPCPLFSAFLGTCLERGRDKAWGGAEYNIGGTILTGVPNMVNTVCAMKKWVFDEG 571

Query: 553 GLAIDFEIEG----------------------------EYPQFGNNDPRVDDLAVDLVER 584
              +D  +E                               P FG+N P  + +   +++ 
Sbjct: 572 KYHLDDVLEAFRNNFVSPQTTNPASQRTYDAIRVDFATNSPLFGSNHPEANAVTRWILDD 631

Query: 585 FMKKIQKLHTYRDAI------------------PTQSVLTITSNVVYGKK------TGNT 620
           +   +    +  D I                          +    +G +       G  
Sbjct: 632 YFDAVMSSKSMADRIFLKKPATTEEEREVKRLRYIAGYFGESFQEKFGPQFNIKFTAG-- 689

Query: 621 PDGRRAGAPF-----------------GPGANPMHGRDQKGAVASLTSVAKLPFAYAKDG 663
             G     P                   P   P  G    G    L S + L       G
Sbjct: 690 -CGTFEQYPLQGAGIAASADRAAAAPLAPNFTPPPGTQINGIGNLLASFSGLGLDRLGAG 748

Query: 664 ISYTFSI-----VPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLD 718
           +     +      P  +    E    N   +M     + A  +    L+          +
Sbjct: 749 VITDLCLDQSQNDPEVIRGIMEQFIANKGNMMTLAIGNSAVYQTIYELSWAASKMSDQTE 808

Query: 719 AMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITR 754
           A+   E+Y  + +RV G+   F +++ +QQ++ I R
Sbjct: 809 AVRKLEEYSAINVRVGGWQAPFITMSLDQQENYINR 844


>UniRef50_Q24T37 Putative pyruvate-formate lyase n=1 Tax=Desulfitobacterium
           hafniense Y51 RepID=Q24T37_DESHY
          Length = 626

 Score =  246 bits (628), Expect = 2e-63,   Method: Composition-based stats.
 Identities = 107/616 (17%), Positives = 214/616 (34%), Gaps = 72/616 (11%)

Query: 175 RGRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLENGVNLEQTIRLREEIAEQHRALGQM 234
            G +  DY      G++    +        + ++     +E  +R    I  Q R +   
Sbjct: 43  YGNLSPDYETFLHGGLN----ELRICDPKTRFEIHRNRIVEIILRYAGRIEAQLREMETT 98

Query: 235 KEM--AAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDL 292
             +  A  +      PA + +EA+Q   F      +  N   +  G     L  + E+ L
Sbjct: 99  TAVLRAKWFSRFADYPAESFEEALQRILFVNQLMWQ-TNHRLVGLGHWDALLGGFYEKGL 157

Query: 293 KAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTK 352
           +   +T ++A  ++    +++  + +        L  GD       +G    +G  + T 
Sbjct: 158 QNRTLTLEDAFSLL-CSALRILHIDY---KFKSNLVLGD-TGQIIVVGASNQNGDYVGTG 212

Query: 353 NSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSI-DTSSLQYENDDLMRPDF- 410
            +   ++ +  +   P+P + +  ++K+P +  + A         S    NDD++ P   
Sbjct: 213 LTDLIISAVKELAQ-PDPKVLLRVNKKMPDDLWETALDCMASGCGSPLLSNDDVIIPHLV 271

Query: 411 -------NNDDYAIACCVSPMIVGKQMQFFGAR-ANLAKTMLYAINGGVDEKLKMQVGPK 462
                  +   Y  + C  P+I GK          N  K     +N  V ++  +Q    
Sbjct: 272 SFGVTPEDACSYITSACWEPLIAGKDSSLNNVTSLNFMK----GLNN-VFQRDNLQ---- 322

Query: 463 SEPIKGDVLNYDEVMERMDHFMDW-------LAKQYITALNIIHYMHDKYSYEASLMALH 515
                  + +Y+E+  R   F+         +  Q     + +  +  K   E+     H
Sbjct: 323 ------KINSYEELKARYRLFLAHNITAVKRVVSQQRFQYDPVLSLFMKGCSESGKDVAH 376

Query: 516 DRDVIRTMACGIAGLSVAADSLSAIK---YAKVKPIRDEDGLAIDFEIEGEYP------- 565
              V   +     GLS   ++L  +K   + +     +E    ++   E   P       
Sbjct: 377 GGAVYHDIGITTVGLSNVVNALLNLKEHVFERHTYTLEEVQSILNDNFENHEPLRKQLSS 436

Query: 566 ---QFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPD 622
               +G +D  V DL  +L+    ++     TY         L+  + +   +    + D
Sbjct: 437 REIAYGVDDSEVIDLTNELIRFVSEQTSDFRTYLGGRLKFG-LSAPAYIDAARDFPASFD 495

Query: 623 GRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAK-DGISYTFSIVPNALGKDDEV 681
           GR+   PF    +             +  VA L     + +G        PN +  +   
Sbjct: 496 GRKMDEPFAVHIS---NEKISAYTTIINFVAALDLGGNRFNGNVIDLMATPNFIHDN--- 549

Query: 682 RKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFN 741
            K  L  L+       A+  G   + +NV N + L++A + P  +P L +RV G++    
Sbjct: 550 -KEKLIALLR-----IATDIGFFQMQMNVFNSKTLIEAKKRPSDFPNLIVRVWGFSAYMI 603

Query: 742 SLTKEQQQDVITRTFT 757
            L +E +  +I R   
Sbjct: 604 DLPEEYKDVLIMRALE 619


>UniRef50_D0RZP3 Formate acetyltransferase n=1 Tax=Acinetobacter calcoaceticus RUH2202
            RepID=D0RZP3_ACICA
          Length = 1302

 Score =  238 bits (606), Expect = 9e-61,   Method: Composition-based stats.
 Identities = 117/746 (15%), Positives = 222/746 (29%), Gaps = 171/746 (22%)

Query: 161  RKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLENGVNLEQ---- 216
            R  G L  L +A G G +I +Y++    G+  L ++ +A+  S     E     E     
Sbjct: 552  RLQGFLRNLSEASGVGHVIPNYKKALDLGLAGLQQE-IAKHASNAQTPEKKDFYEASRLA 610

Query: 217  ----------TIRLREEIAEQHRALGQMKE-----MAAKYGYDISGPATNAQEAIQWTYF 261
                        +L  ++A Q +   + +      +  +             +A+Q+ + 
Sbjct: 611  LTGISEYFLNYSKLAFKVAGQMQKGQEFERDNLIAIGRRMEKLSKDKPDTFIDAVQFIFT 670

Query: 262  GYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRF--- 318
             +       NG   +FGR    L  ++E+D     I  +EAQE++D   +KL        
Sbjct: 671  LHSCLHL--NGEPTAFGRMDQLLHPFLEKD----AIPPEEAQEIIDAFYIKLDEKVQQNR 724

Query: 319  --------LRTPEYDELFSGDPIW-------ATESIGGMGLDG-------RTLVTKNSFR 356
                                 P            ++GG   DG       +    + +  
Sbjct: 725  MFMEDHQPFGNLAMGGSSGPYPQGASLGQWIQQITVGGTVADGEEDFSKTKPAYNEVTKL 784

Query: 357  FLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAK-VSIDTSSLQYENDDLMRPDFN---- 411
            F+     + P   P +++   + +P    + AA  +    +     ND+ + P  +    
Sbjct: 785  FIRASGRL-PLNAPCLSLRTRKDIPEEILEVAAHAILSGGAHPILLNDEKLIPSLHQSGN 843

Query: 412  ---------------------NDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGG 450
                                   +YA   C  P   G+     G   +  + +  A+N G
Sbjct: 844  GVGGDALTNLPNWNSKVDIRSAQNYACDGCYEPQFPGENWFSLGG-FSTLQPLECALNQG 902

Query: 451  V-------DEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHD 503
                           V   ++P    + +++E++E      + L ++      + +  + 
Sbjct: 903  KTISSAGQSYLFGQTVSLNTKP-ADQIDSFEELLELYKQHFELLNRKAFNGQILGYGANT 961

Query: 504  KYSYEASLMALHDRDVIRTMACGIAG------------LSVAADSLSAIK-------YAK 544
                   L  L D  + +       G            LS   +SL AIK        A 
Sbjct: 962  DICPSPILNVLMDDCLAKGQDFYSGGAKYNIYGPCYISLSNTINSLYAIKAMVFDPLTAV 1021

Query: 545  VKPIRDEDGLAIDF----------EIEGEY-------------------PQFGNNDPRVD 575
                   + L  D+           + G                     P++G  +P VD
Sbjct: 1022 TTLPELLECLCCDWGYKMTEPFISNLAGHARIAAQADRYKRLREIALAQPRYGRGNPEVD 1081

Query: 576  DLAVDLVERF----------------------MKKIQKLHTYRDAIPTQSVLTITSNVVY 613
             L  ++V+                         +                V T  ++V  
Sbjct: 1082 KLGDEIVKMIAEISVKTFTHPWPQFAQSLKSLAECYGSKEHPFGIQIQPGVGTFENHVEM 1141

Query: 614  GKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKD-----GISYTF 668
            G   G + DGRR G       +P                 K+ F+ A       G +   
Sbjct: 1142 GAWNGASADGRRLGTTVASDLSPSPS-----PADLAIDHQKVEFSRALQGFEGIGTNLMA 1196

Query: 669  SIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQ 728
               P      ++     L  ++  +    +       L + V + E    A+ +PE+Y  
Sbjct: 1197 DGAPTDFNIGEDFGVQELVAILKQF----SQGSSSNILTITVADPETFAQAVTSPEQYNL 1252

Query: 729  LTIRVSGYAVRFNSLTKEQQQDVITR 754
            L +R  G++  F S+    Q+    R
Sbjct: 1253 LRVRTGGWSNFFTSVFPTIQEQHQRR 1278


>UniRef50_Q2HBR9 Putative uncharacterized protein n=1 Tax=Chaetomium globosum
            RepID=Q2HBR9_CHAGB
          Length = 1229

 Score =  227 bits (578), Expect = 1e-57,   Method: Composition-based stats.
 Identities = 115/719 (15%), Positives = 221/719 (30%), Gaps = 147/719 (20%)

Query: 169  LPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLENGV---------------N 213
            L +    G I+  Y  +   G+  ++ D   +   +                        
Sbjct: 479  LNEWSAMGHIVPGYDLLVRDGLKKMITDIKDKLAKVSDPASATASFYESCIISLEGVQGY 538

Query: 214  LEQTIRLREEIA-----EQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVK 268
            L    ++ +  A          +  MK++ A+          + Q+A+Q  Y  +     
Sbjct: 539  LRNWAKIAQRAAIAAGMTAPDDVANMKDVEARMNRLADDAPESFQDAVQLIYSFHCCLHL 598

Query: 269  SQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELF 328
               G    FGR    L  Y+ +    G  T + AQE++D L +K+    F+      +  
Sbjct: 599  V--GELTPFGRLDQILYPYLSK---GGGTTLEHAQEIIDCLWVKIGENAFVNRAFIYDYV 653

Query: 329  SGDPIWATESIGGMGLDGRT-----------------------LVTKNSFRFLNTLYTMG 365
            +     A   +GG    G                              +   L     + 
Sbjct: 654  T-YGTTAVCGLGGNFPQGGGINQWVQQITVGGYKATDSATPECGANAVTMLCLKAARRI- 711

Query: 366  PSPEPNMTILWSEKLPLNFKKFAAK-VSIDTSSLQYENDDLMRPDFN------------N 412
            P   P +++   + +P  +   AAK +    +     NDD + P               +
Sbjct: 712  PVNAPTLSLRVHKDIPHEYLDEAAKGILSGGAQPILYNDDKLCPALKDSATANVVDLKWS 771

Query: 413  DDYAIACCVSPMIVGKQMQFFGARANLA--KTMLYAINGGV-------DEKLKMQVGPKS 463
             DYA   C  PM+ G     F    N+A    +   +N G        ++   ++   +S
Sbjct: 772  RDYAADGCYEPMLAGASEFTFN---NVAPLLALEQTLNEGSTYGEAGPEQLRGLKQTFRS 828

Query: 464  EPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRT- 522
            +P K +  +++++ +     ++WL  Q    +   +           L  L    V +  
Sbjct: 829  KPAK-EFKSFEDLKDTFVKQLEWLVVQCYNTMLDGYGNLANVCPSPLLSVLIQGCVEKGR 887

Query: 523  -----------MACGIAGLSVAADSLSAI-------KYAKVKPIRDEDGLAIDF------ 558
                       MA    G+S   DSL AI       + A+V        L  D+      
Sbjct: 888  DLTNGGSKFHIMAPLCVGMSNTIDSLYAIQKLVFDDETARVTLQELVKCLICDWGHNMIE 947

Query: 559  --------------------EIEGEY---PQFGNNDPRVDDLAVDLVERFMKKIQK---- 591
                                E+       P++G+ D  V+ L   LV+  +    K    
Sbjct: 948  PYENQLSGTADASERGLRYSELRNAALALPKWGSGDEEVNKLGDWLVQTCVDLCVKAIRH 1007

Query: 592  ---------------LHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANP 636
                                + I    + T    V  G   G + DGRR+G P     +P
Sbjct: 1008 PNATIKAHLDNIKKTYGEDFEFIICPGIGTFEGYVGDGIPCGASADGRRSGMPIASDLSP 1067

Query: 637  MHGRDQKGAVASLTSVAKLPFAYAKDGISYTF-SIVPNALGKDDEVRKTNLAGLMDGYFH 695
            +       A  +  ++ +   +   + I +   +  P  +   +      L   +  Y  
Sbjct: 1068 VPAAQDLPASPAFRNIYQAMESTKYNSIEHGLSNAAPVDMNIPESFPLPELQKFVKKY-- 1125

Query: 696  HEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITR 754
              A   G   + +   + +    ++ +PEKY  + +R+ G+   + ++    Q     R
Sbjct: 1126 -AAGEVGSNLITLTCADLDTYQKSVRDPEKYNLVRVRMGGWTEFYATMFPAHQDQQQRR 1183


>UniRef50_C3Z558 Putative uncharacterized protein n=3 Tax=Branchiostoma floridae
            RepID=C3Z558_BRAFL
          Length = 1619

 Score =  222 bits (566), Expect = 3e-56,   Method: Composition-based stats.
 Identities = 120/791 (15%), Positives = 233/791 (29%), Gaps = 176/791 (22%)

Query: 125  AYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRR 184
             Y    D +I  +   +     + V    T +    +      G+ +A   G ++ DY+ 
Sbjct: 458  LYRIHPDELIVGVMPSFSMGLGKRVMPYLTDE---EQIPAYQMGVTEAAAIGHVVPDYQV 514

Query: 185  VALYGIDYLMKDKLAQFTSLQ-------ADLENGV--------------NLEQTIRLREE 223
            +   G+  L+ D   + + L+        + E  +               ++   +L + 
Sbjct: 515  ILDKGLQALIDDIDDKLSKLETLVLSRREEKERAMFYHSIKMSLMGVQEYIKSYAQLADN 574

Query: 224  IAEQ----HRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGR 279
            +A+          +++++  +     +       EA Q  +  +        G  +S GR
Sbjct: 575  LADNETFTKAQATKLRQIGHRMSTLATHKPKTFLEATQLVFTMHCCLHIV--GEPISIGR 632

Query: 280  TSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFL-RTPEYDELFSG-------- 330
                L  +  +D     +T +EAQE++D   +K+     L R    D++F G        
Sbjct: 633  LDQLLGPFYRQD----SLTMEEAQEIIDCFWIKVGERTLLNRHAAQDKIFPGMGAVPYTS 688

Query: 331  ----------DPIWATESIGGMGLDG----RTLVTKNSFRFLNTLYTMGPSPEPNMTILW 376
                      +      +IGG   +      +     +   L     + P   P +T+  
Sbjct: 689  SGNFPQGGCMNQWGQQLTIGGYLPNEDTVPTSACNPVTLMCLRAARRL-PLNAPCLTLRL 747

Query: 377  SEKLPLNFKKFAAKVSIDTSS-LQYENDDLMRPDF-------------NNDDYAIACCVS 422
            ++  P    + AAK  +   +     +DD + P               +  +Y    C  
Sbjct: 748  NKDTPEEVLEEAAKALLSGGAHPVLLHDDRLIPALLDSGRRGIPVSLEDARNYTCDGCFE 807

Query: 423  PMIVGKQMQFFGARANLAKTMLYAINGG---------VDEKLKMQVGPKSEPIKGDVLNY 473
            P+ VG     F     L   +  A+N G              K     K+      ++ +
Sbjct: 808  PVFVGASEFAFCTFP-LLDAVEMALNEGTLYSQAGPHFLRGSKKSFPSKN---ATQIITF 863

Query: 474  DEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRT----------- 522
            ++        +       ++ L   +    K      L  +    V              
Sbjct: 864  EQFQGIFVEHLQLQIPLLVSFLVGGYGNIWKMCPSPLLSVMMKGCVEACRDHTNGGTKYH 923

Query: 523  -MACGIAGLSVAADSLSAIKY-------AKVKPIRDEDGLAIDF---------------- 558
             +     G + A DSL AIK        A          L  D+                
Sbjct: 924  DLGFMFVGAANAIDSLYAIKKLVYDPLTALTTLPDLLTCLKCDWGHDMKEYIFDARGGSA 983

Query: 559  -------------EIEGEYPQFGNN-DPRVDDLAVDLVERF------------------M 586
                         E+   +P+FG+  +  + +L   + E                     
Sbjct: 984  RKEAKASAFKHLREVATSFPKFGHGENAELKELGTWMFENVLTILRETFDNAKPGVKETF 1043

Query: 587  KKIQKLHTYRDAIPT----------QSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANP 636
            ++++K +                    + T  + V YG  +  + DGRR+G P     +P
Sbjct: 1044 ERLEKEYYIPGDPDNPERRFGFVVLPGIGTFEAYVGYGLNSAASADGRRSGQPIASDLSP 1103

Query: 637  MH-------GRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGL 689
                       D      +L             G+S    +    L   ++     L   
Sbjct: 1104 APVPQDLPANPDSCDIYKALKC---WDIERINLGLSCGSEVDLMIL---EDFPLDKLTEF 1157

Query: 690  MDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQ 749
            +  Y   +  I G   + V   N E L  A +  + Y  + +R  G+   F +L  E Q 
Sbjct: 1158 LRRYADLDGPI-GSNVITVTCANPETLEKASKVTDAYELVRVRQGGWTEFFITLFPEHQG 1216

Query: 750  DVITRTFTQSM 760
             +  R     M
Sbjct: 1217 QLRRRIDANKM 1227


>UniRef50_O94132 Formate C-acetyltransferase (Fragment) n=2 Tax=Piromyces sp. E2
           RepID=O94132_9FUNG
          Length = 154

 Score =  209 bits (531), Expect = 4e-52,   Method: Composition-based stats.
 Identities = 74/152 (48%), Positives = 111/152 (73%), Gaps = 2/152 (1%)

Query: 24  VNVRDFIQKNYTPYEGDESFL-AGATEATTTLWDKVMEGVKLENRTHAPVDFDTAVASTI 82
           ++V  +I++N+TPYEGD SFL   A+  T  +W+K  E    E +T+  +D D    ST+
Sbjct: 4   IDVAKWIKENHTPYEGDASFLVTDASAKTKDVWNKCCELRAEEIKTNGCLDVDNKTISTV 63

Query: 83  TSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIKMIEGSCKAYNRELDPMIKKIFTEYR 142
            SH+AGYI K+ E IVGLQT+APLKR++ PFGG+++++ + KAY+R +DP ++++F +YR
Sbjct: 64  NSHEAGYIIKEKEDIVGLQTDAPLKRSIKPFGGVRIVKNALKAYDRTIDPSVEEVF-KYR 122

Query: 143 KTHNQGVFDVYTPDILRCRKSGVLTGLPDAYG 174
           KTHN  VFD+YTP++ + R + +LTGLPD YG
Sbjct: 123 KTHNDCVFDIYTPEMRKARSNAILTGLPDGYG 154


>UniRef50_A3RV69 Formate acetyltransferase n=5 Tax=Ralstonia solanacearum
            RepID=A3RV69_RALSO
          Length = 1352

 Score =  186 bits (472), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 118/748 (15%), Positives = 219/748 (29%), Gaps = 191/748 (25%)

Query: 169  LPDAYGRGRIIGDYRRVALYGIDYL---MKDKLAQFTSLQADLENGV------------- 212
            L    G G ++  Y  +  YGI  L   + +      +                      
Sbjct: 618  LGPTSGVGHVVPGYEALLAYGISGLSGRIDEAQQALAATDPQRAEEAKSFYAGARLALRG 677

Query: 213  ---NLEQTIRLREEIAEQHRALGQMKE-----MAAKYGYDIS-GPATNAQEAIQWTYFGY 263
                L+   +   E A+      +++      M  +     S        EA+Q     +
Sbjct: 678  LAEYLDGLAQTAHETAQALPQDQEIERKNLEAMQHRLQRLASGAAPETVLEALQLVLACH 737

Query: 264  LAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFL---- 319
                    G  ++ GR    +  + E+      + E + QE +D   +KL     L    
Sbjct: 738  ATLHL--CGEPVAVGRLDRLIRPFQEKS----PLDEAQLQEAIDCFWLKLGEKALLNRIF 791

Query: 320  --------------RTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMG 365
                          R   Y +  S +      ++GGM  DG    +  +   L     + 
Sbjct: 792  IDDHQELGNLAMGNRAGPYPKGQSVNQWIQQITVGGMNADGSWEYSDVTLACLRASSRL- 850

Query: 366  PSPEPNMTILWSEKLPLNFKKF-----AAKVSIDTSSLQYENDDLMRPDF---------- 410
            P   P +++  S+ +P  ++K      A       +S    NDD + P            
Sbjct: 851  PFNAPVLSLRVSKDMPSVWRKRLLAEAARGQLSGGASPILLNDDKIIPALSSSGIGIGPR 910

Query: 411  ----------------NNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEK 454
                            +  DYA   C  P  VG      G    L + +  A++ G   +
Sbjct: 911  ANADEAARWNSTVRREDAHDYACDGCYEPQFVGANWFHLGG-VTLLQMLEVALDQGRQMQ 969

Query: 455  L-------KMQVGPKSEPIKGDVLNYDEVMERMDHFMDW-LAKQYITALNIIHYMHDKYS 506
                       V  +S P    + +Y E+       ++W  A+Q      +  +      
Sbjct: 970  SAGPIDLLGKNVSFRSPPATA-IASYAELEGLFFKHLEWTYARQM--EGTVADFGRMDGV 1026

Query: 507  YEASLMALHDRDVI---RTMACGIA----------GLSVAADSLSAIK-----YAKVKPI 548
              + L+ L   D +   R +  G A           L+   ++L AI+      A     
Sbjct: 1027 CPSPLLNLFIHDCLDKGRDIYAGGARYNVFGPCFTSLANTINALWAIRVMCFDQATAITT 1086

Query: 549  RDEDGLAIDFEIEGEY----------------------------------PQFGNNDPRV 574
              E   A+                                          P++G  +  +
Sbjct: 1087 LSELVQALLCNWGENVIDPLVHPTVLAGDATRASQAATRFRQLRSIALSLPRWGRGNADI 1146

Query: 575  D-----------DLAVDLV--------ERFMKKIQKL----HTYRDAIPTQSVLTITSNV 611
            D           ++AV ++        +++ +K        H +        V T  S V
Sbjct: 1147 DTFGNTICQRVAEIAVRVMAQPRDGLADQYRRKAMAYGTPAHPFGGFCMQPGVGTFASYV 1206

Query: 612  VYGKKTGNTPDGRRAGAPFGPGANPMHG-----------RDQKGAVASLTSVAKLPFAYA 660
              G     + DGR +G P G   +P              +   G  A L  +        
Sbjct: 1207 EQGLGCSASADGRLSGQPLGTDMSPAPSPLDLPATDASQQRVDGVRA-LKGIRATDAFGF 1265

Query: 661  KDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAM 720
             +G     +I       D+ + ++ L  ++D +       +G   L V   ++   L A 
Sbjct: 1266 ANGAPVDLNI-------DEHMGESRLVEILDAFVD----GDGSNILTVTTADQATFLAAA 1314

Query: 721  ENPEKYPQLTIRVSGYAVRFNSLTKEQQ 748
             +PE +  L +R+ G+   F ++    Q
Sbjct: 1315 NSPESFDLLRVRMGGWTEMFVAMHATHQ 1342


>UniRef50_D1NCN8 Formate C-acetyltransferase n=1 Tax=Haemophilus influenzae HK1212
           RepID=D1NCN8_HAEIN
          Length = 218

 Score =  181 bits (459), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 119/131 (90%), Positives = 127/131 (96%)

Query: 599 IPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFA 658
           +PTQSVLTITSNVVYGKKTGNTPDGRR+GAPFGPGANPMHGRDQKGAVASLTSVAKLPFA
Sbjct: 1   MPTQSVLTITSNVVYGKKTGNTPDGRRSGAPFGPGANPMHGRDQKGAVASLTSVAKLPFA 60

Query: 659 YAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLD 718
           YAKDGISYTFSIVPNALG D E ++ NLAGLMDGYFHHEA++EGGQHLNVNV+NREMLLD
Sbjct: 61  YAKDGISYTFSIVPNALGNDAEAQRRNLAGLMDGYFHHEATVEGGQHLNVNVLNREMLLD 120

Query: 719 AMENPEKYPQL 729
           AMENP+KYPQL
Sbjct: 121 AMENPDKYPQL 131


>UniRef50_B7BHI6 Putative uncharacterized protein (Fragment) n=1 Tax=Parabacteroides
           johnsonii DSM 18315 RepID=B7BHI6_9PORP
          Length = 178

 Score =  159 bits (401), Expect = 5e-37,   Method: Composition-based stats.
 Identities = 49/104 (47%), Positives = 68/104 (65%), Gaps = 1/104 (0%)

Query: 12  WEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLWDKVMEGVKLENRTHAP 71
           W  F    W+ E+NVRDFIQ NY PY+GD++FL  ++E T  +W+K+ E  K+E R    
Sbjct: 76  WAQFKGETWKKEINVRDFIQNNYKPYDGDDTFLVPSSEKTKKVWNKLTEMFKVE-REKGV 134

Query: 72  VDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGG 115
            D +T +   I ++  GYI+K+ E IVGLQT+APLKR + P GG
Sbjct: 135 YDAETKLPQGIDTYGPGYIDKENEVIVGLQTDAPLKRGIFPKGG 178


>UniRef50_Q7NEY2 Glr3745 protein n=1 Tax=Gloeobacter violaceus RepID=Q7NEY2_GLOVI
          Length = 460

 Score =  147 bits (372), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 82/223 (36%), Positives = 117/223 (52%), Gaps = 18/223 (8%)

Query: 181 DYRRVALYG-IDYLMKDKLAQFTSLQADLENGVNLEQTIRLREEIAEQHRALGQMKEMAA 239
           D R   +YG ID L  ++L     + +D                +  Q  A+  ++ +A 
Sbjct: 158 DRREELIYGLIDPLDVEQL----PVGSDCRQLALY--GSERLRRLGMQLGAVETVEALAG 211

Query: 240 KYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITE 299
            YG DI  PA  AQ+AIQWTY   LA      G   S     TF DVY +RDL  G + E
Sbjct: 212 CYGLDIGRPAATAQQAIQWTYLALLATRDPLFGRRRSVTGLDTFFDVYFQRDLARGLLVE 271

Query: 300 QEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLN 359
           +EAQE+VD L++KLR+ +   +  Y  L +           G+  +GR LVT+  FRF+N
Sbjct: 272 EEAQELVDDLMIKLRLPQPTLSELYLPLAA-----------GVDPEGRPLVTRTDFRFVN 320

Query: 360 TLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSSLQYEN 402
           T Y +GP+ EP++ +LWS  L   F++F  +V+IDTSSL+Y  
Sbjct: 321 TCYNLGPAAEPHLLVLWSAALSGAFRRFCGEVTIDTSSLRYAR 363



 Score = 95.5 bits (236), Expect = 7e-18,   Method: Composition-based stats.
 Identities = 34/106 (32%), Positives = 48/106 (45%), Gaps = 4/106 (3%)

Query: 9   ATAWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLWDKVMEGVKLENRT 68
           A  W+GF  G+WQ   +V +FI  N  PY GD+S L G TE T  LW +     +    T
Sbjct: 78  ADPWQGFRPGNWQVRTDVENFIAANCDPYLGDDSDLTGPTERTQALWVQAQMLQQAARAT 137

Query: 69  HAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFG 114
                      +   +  A Y++++ E I GL    PL    +P G
Sbjct: 138 ARRSAGPGGTPAG--AFGADYLDRREELIYGLI--DPLDVEQLPVG 179



 Score = 67.0 bits (162), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 32/107 (29%), Positives = 52/107 (48%), Gaps = 11/107 (10%)

Query: 646 VASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQH 705
            +SL     LP    + G+++T    P+ALG     +  NL   +DG          G H
Sbjct: 356 TSSLRYARALPLP--QTGLAHT--FSPDALGATRTEQVENLGLWLDGQPE-------GDH 404

Query: 706 LNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVI 752
           L +NV  RE LL  +  P K+  LT++++  AV  +SL+   ++ V+
Sbjct: 405 LGINVFGREALLSTLTRPNKFAHLTVQLAEGAVDLHSLSPLGRRQVL 451


>UniRef50_UPI0001C3572E putative pyruvate-formate lyase n=1 Tax=Clostridium hathewayi DSM
           13479 RepID=UPI0001C3572E
          Length = 395

 Score =  147 bits (371), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 69/410 (16%), Positives = 137/410 (33%), Gaps = 65/410 (15%)

Query: 251 NAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLV 310
           + +EA+Q   F + +         +  GR    L  Y        K+   E+ +++    
Sbjct: 21  SLEEALQRILF-WSSLFWQSQHTLVGIGRLDKVLARY--------KLDIPESVQIIGDFY 71

Query: 311 MKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEP 370
                +      +      GD       +GG+  +G     + +  F+  +    P P+P
Sbjct: 72  ---SEMHRYFAFKSSGKLLGD-TGQIIVLGGIDPNGDYFCNEYTHIFIEVMRD-KPIPDP 126

Query: 371 NMTILWSEKLPLNFKKFAAK-VSIDTSSLQYENDDLMRPDF--------NNDDYAIACCV 421
            + +  S K+P +  + A + ++         NDD++ P          +  +Y  + C 
Sbjct: 127 KILLRISSKMPDDLLELAIQCIATGVGCPLLSNDDVIIPALEEFGYTHADACNYVTSACW 186

Query: 422 SPMIVGKQMQFFGAR-ANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERM 480
            PM  GK ++    +  N  +      N   DE                  N++ ++   
Sbjct: 187 EPMAYGKSLEKNNIKSINFGRCFEKTYNN--DEFT-------------ACKNFEGLLTLF 231

Query: 481 DHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACG------------IA 528
            + +D  A+  I  LN I     ++          +  +++                   
Sbjct: 232 LNEVDREAETVINILNNI-----RWEKNPLRSLFTEDCIVKGKDISEGGATYNNYGVLTV 286

Query: 529 GLSVAADSLSAIK---YAKVKPIRDED---GLAIDFE-IEGEYPQ-FGNNDPRVDDLAVD 580
           GL+ A DSL  IK   + + K   D+        +FE ++    + +G  + +V  L   
Sbjct: 287 GLANAVDSLLNIKELCFEEKKFTLDQVRSICRESNFESVDSSLKKWYGTENTQVAQLVEQ 346

Query: 581 LVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPF 630
           + +R    +               L+ ++ V  G   G T DGR    P 
Sbjct: 347 MTDRVYNNLSSYRNRFYGKVKWG-LSASNYVESGAVVGATFDGRNKNEPL 395


>UniRef50_UPI00019247E5 PREDICTED: hypothetical protein, partial n=1 Tax=Hydra magnipapillata
            RepID=UPI00019247E5
          Length = 1179

 Score =  130 bits (328), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 76/489 (15%), Positives = 153/489 (31%), Gaps = 98/489 (20%)

Query: 169  LPDAYGRGRIIGDYRRVALYGIDYLMKD-------------KLAQFTSLQADLENGVNLE 215
            L +  G G +I +Y+++   G+   +K+             K   +  L A       LE
Sbjct: 545  LSETSGFGHVIPNYQKIIQKGLPTFLKEIKSYMDLSTDSMKKEFYWCCLTAFKGIQKYLE 604

Query: 216  QTIRLREEIAEQ-----------HRALGQMKEMAAKYGYDI------SGPATNAQEAIQW 258
                L   +A +                ++  MA +  +        SG   N  EA Q 
Sbjct: 605  NYANLALFLANRGVEKDIHFAISSTECNELYSMAQRLNWLANGNGNGSGKPRNFLEATQL 664

Query: 259  TYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRF 318
             +  +           +S GR    L+ + +         ++  Q++VD   +K+     
Sbjct: 665  LFTLHCCLHL--CCEPVSIGRFDVILEEFFDP-------NDRSNQDVVDAFWIKIGEKVQ 715

Query: 319  LRTPEYDELFS---------GDPIW----------ATESIGGMGLD--GRTLVT-----K 352
            L      +L++          D ++             +IGG   D  G  ++      +
Sbjct: 716  LNRETRLDLYTVGTIAVPYRSDGMFARGDGCNQWVQQLTIGGFVADDSGERVLPSAKRIE 775

Query: 353  NSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAA-KVSIDTSSLQYENDDLMRPDFN 411
             S   L +   + P   P +++     +     K AA  +    +     +DDL+ P   
Sbjct: 776  ISKLCLRSARRL-PLNAPCLSLRVYSGMDDILLKEAAYTILSGGAHPVLPHDDLLIPALI 834

Query: 412  ND--------DYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVD-------EKLK 456
            N         +Y+   C  P++ GK   F  A   L   +   +N G             
Sbjct: 835  NTGLNPKDAINYSSDGCYEPIVPGKTE-FSFAYVALLPILEMTLNRGATISNAGPAGMRG 893

Query: 457  MQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHD 516
              V     P  GD+ + D++ +     +       ++ L   +   +       L ++ D
Sbjct: 894  YAVSRDLRPDSGDIKSLDDIKKHFGMHLRLQMNDALSGLLSNYGNINTILTTPLLSSMID 953

Query: 517  RDVIRT------------MACGIAGLSVAADSLSAIKYAKVKPIRDEDGLAIDFEIEGEY 564
              + +             +   +   +   DSL AI+        D+  + +D  +    
Sbjct: 954  GCLEKGRDHYNGGAELKMIGLMVVSFANTVDSLYAIQELCF---GDKSFITLDQLVRTLQ 1010

Query: 565  PQFGNNDPR 573
              +G +   
Sbjct: 1011 SDWGFDLQE 1019



 Score = 49.7 bits (117), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 36/237 (15%), Positives = 65/237 (27%), Gaps = 40/237 (16%)

Query: 417  IACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEV 476
            I  C+     G+     GA   +   M+ +    VD    +Q   +        +  D++
Sbjct: 952  IDGCLE---KGRDHYNGGAELKMIGLMVVSFANTVDSLYAIQ---ELCFGDKSFITLDQL 1005

Query: 477  MER------MDHFMDWLAKQYITALNIIHYMHDKYSYEASLM----ALHDRDVIRTMA-- 524
            +         D    W           I   + K   E +L      L  ++  R     
Sbjct: 1006 VRTLQSDWGFDLQEPWFDPVDGEIGKQISAANMKLIREVALSLPKLGLATKENERNKNTL 1065

Query: 525  ---CGIAGLSVAADSLSAIKYAKVKPIRDEDGLAIDFEIEGEYPQFGNNDPRVDDLAVDL 581
               C I  L   A  L+         +       ++  ++    ++G +D +        
Sbjct: 1066 SSYCPIT-LKEIASWLAKEIVLAFTEVTTLPKYTLNNIVKSLTEKYGTSDEK-------- 1116

Query: 582  VERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMH 638
                         +          T    V +G   G + DGRR G P     +P  
Sbjct: 1117 --------NGKKPF--INFQLGSGTFEGYVGWGLGIGASADGRRKGQPLASDMSPAP 1163


>UniRef50_B1EF41 Keto-acid formate acetyltransferase (Keto-acid formate-lyase) n=3
          Tax=Enterobacteriaceae RepID=B1EF41_9ESCH
          Length = 96

 Score =  125 bits (313), Expect = 8e-27,   Method: Composition-based stats.
 Identities = 55/82 (67%), Positives = 69/82 (84%)

Query: 5  NEKLATAWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLWDKVMEGVKL 64
          ++  A AW GF   DW++E+NVRDFIQ NYTPYEGDESFLA AT ATT LW+KVMEG+++
Sbjct: 9  DKLYANAWLGFKGTDWKDEINVRDFIQHNYTPYEGDESFLAEATPATTALWEKVMEGIRI 68

Query: 65 ENRTHAPVDFDTAVASTITSHD 86
          EN THAP+DFDT +A+TIT+H+
Sbjct: 69 ENATHAPLDFDTNIATTITAHE 90


>UniRef50_UPI0001C420E7 pyruvate-formate lyase Pfl n=1 Tax=Methanobrevibacter ruminantium
           M1 RepID=UPI0001C420E7
          Length = 677

 Score =  121 bits (303), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 104/654 (15%), Positives = 209/654 (31%), Gaps = 122/654 (18%)

Query: 134 IKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYL 193
           IK +  +   T +   F  +  +       G +   P  Y    +I DY    L    + 
Sbjct: 64  IKNLLRKLDITIHPEGFIYFLDEFRNLDYHGQIINSPIDYS---LILDYSIYDLNEFYFN 120

Query: 194 MKD----KLAQFTSLQADLENGVNLEQTI-RLREEIAEQHRALGQMKEMAAKYGYDISGP 248
            K+    +       +  L     +E  I  + + +A+  R      +    +   I   
Sbjct: 121 PKEGPGFRNQSSDYNREMLAILDGIELLIYEINKALAKSSRDDK--SKYIRIFEDIIDKK 178

Query: 249 ATNAQEAIQWTYFGYLAAVKSQNGAAM-SFGRTSTFLDVYIERDLKAGKITEQEAQEMVD 307
           A++ +EA+Q   F        Q G ++ S GR    L+ Y   DL  G IT +EA E++ 
Sbjct: 179 ASHFEEALQRILFLNQLLY--QTGHSLNSLGRLDRILEDYYYNDLNDGYITNKEALELIK 236

Query: 308 HLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLD--GR-TLVTKNSFRFLNTLYTM 364
             +  L    + +T +   L S        ++GG  +D  G        ++ FL  +  +
Sbjct: 237 DFLKALDSYSWYKTDDESGLAS-----QLITLGGKYIDEFGEYYFYNDLTYIFLEAIGQV 291

Query: 365 GPSPEPNMTILWSEKLPLNFKKFAAKVSIDT----------------------------- 395
            P  +  + +  S K P +    A     +                              
Sbjct: 292 NPK-DVKIALRLSYKTPDDLIHLALDCLNENTIYIEEGVAVSFIIDNRIFTADGATIEAN 350

Query: 396 --SSLQYENDDLMRP--------DFNNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLY 445
             S++ + ND+ + P          +  +Y ++  + P  +    +   +  +L K    
Sbjct: 351 IDSNIVFSNDEAIIPRLLDFGYSSDDAYNYILSAHLEPTFISCLDEGNLSSISLLKP--- 407

Query: 446 AINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKY 505
            +N   ++K +++           ++N D +ME   + +    ++ I+AL+ I +  D +
Sbjct: 408 -LNDIFEDKNELRF----------IINLDYLMELYKNNLKKEIEEKISALDQIQWNQDPF 456

Query: 506 -------SYEASLMALHDRDVIRTMACGIAGLSVAADSLSAIKYAKVKP-----IRDEDG 553
                  SYE  L                 GL    +SL  +K    +      I  +  
Sbjct: 457 LSLFSAESYENQLDISQGGSRNNHFGIRFYGLQNTVNSLYNLKKIVFEDKTIDLIELDKM 516

Query: 554 LAIDFE----------IEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQS 603
              +F+          ++    +F  N+P + +++ +++      I+      D      
Sbjct: 517 RKNNFKRGKYQETFLLLKNNPVRFPQNNPEIANISNEIIAFIGDSIKDYKNSLDGKLKFG 576

Query: 604 VLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDG 663
           +      +   K+   + D      P                   L S  K         
Sbjct: 577 LSAPRYMIKNDKR--ASFDATLKDIP---------------PARLLISSQKTNSDIFIFN 619

Query: 664 ISYTFS---IVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNRE 714
            S  +    I  N +  +       L  ++      EA   G   L +N++  E
Sbjct: 620 SSLDYKSSAINGNLIELNINTNDKQLTNIL-----VEAIGYGFDQLQINLIREE 668


>UniRef50_A6BGV7 Putative uncharacterized protein n=1 Tax=Dorea longicatena DSM
           13814 RepID=A6BGV7_9FIRM
          Length = 121

 Score =  113 bits (282), Expect = 3e-23,   Method: Composition-based stats.
 Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 1/103 (0%)

Query: 581 LVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGR 640
           +      +I+   +    + T  +L ++ N   G + G  P GR A  P   G +P  G 
Sbjct: 1   MFAFIANEIESYRSKFGTM-TPGILPVSGNTPVGLEVGALPSGRHAWKPLADGVSPNGGT 59

Query: 641 DQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRK 683
           D +G  A L SV+ LP      G      I P  L  ++ +  
Sbjct: 60  DTEGPGAVLKSVSHLPHDRFVQGTFLNMKIEPEILNSENGIMP 102


>UniRef50_B7UH18 Autonomous glycyl radical cofactor n=257 Tax=root RepID=GRCA_ECO27
          Length = 127

 Score =  107 bits (267), Expect = 2e-21,   Method: Composition-based stats.
 Identities = 49/66 (74%), Positives = 57/66 (86%)

Query: 695 HHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITR 754
             E  +EGGQHLNVNV+ RE L DA+++PEKYPQLTIRVSGYAVRFNSLT EQQ+DVI R
Sbjct: 62  KPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSGYAVRFNSLTPEQQRDVIAR 121

Query: 755 TFTQSM 760
           TFT+S+
Sbjct: 122 TFTESL 127


>UniRef50_Q70BJ5 Putative uncharacterized protein n=4 Tax=Siphoviridae
           RepID=Q70BJ5_BPBF2
          Length = 122

 Score =  107 bits (266), Expect = 2e-21,   Method: Composition-based stats.
 Identities = 49/66 (74%), Positives = 58/66 (87%)

Query: 695 HHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITR 754
                IEGGQHLNVNV++R+ LLDA ++PEKYPQLTIRVSGYAVRFN+LT+EQQ DVI+R
Sbjct: 57  EVAPQIEGGQHLNVNVLSRDQLLDAQKHPEKYPQLTIRVSGYAVRFNALTREQQNDVISR 116

Query: 755 TFTQSM 760
           TFTQ+M
Sbjct: 117 TFTQAM 122


>UniRef50_Q56EP5 Vs.6 n=5 Tax=unclassified T4-like viruses RepID=Q56EP5_9CAUD
          Length = 122

 Score =  106 bits (264), Expect = 4e-21,   Method: Composition-based stats.
 Identities = 52/79 (65%), Positives = 63/79 (79%), Gaps = 6/79 (7%)

Query: 688 GLMDG----YFH--HEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFN 741
            ++ G    +F    E ++EGGQHLNVNV++R  L DA+ NPEKYPQLTIRVSGYAVRFN
Sbjct: 44  SVIRGRPGRFFDVQSEPTVEGGQHLNVNVLDRNTLEDAIVNPEKYPQLTIRVSGYAVRFN 103

Query: 742 SLTKEQQQDVITRTFTQSM 760
           +LT EQQ+DVITRTFTQS+
Sbjct: 104 ALTPEQQRDVITRTFTQSL 122


>UniRef50_Q5E2Y6 Autonomous glycyl radical cofactor n=6 Tax=Proteobacteria
           RepID=GRCA_VIBF1
          Length = 125

 Score =  103 bits (256), Expect = 4e-20,   Method: Composition-based stats.
 Identities = 48/70 (68%), Positives = 56/70 (80%)

Query: 691 DGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQD 750
           D        IEGGQHLNVNV+ R+ L DA+++PE YPQLTIRVSGYAVRFNSLT EQQ+D
Sbjct: 56  DVAIEKAPKIEGGQHLNVNVLQRDTLEDAVKHPENYPQLTIRVSGYAVRFNSLTTEQQKD 115

Query: 751 VITRTFTQSM 760
           VI RTFT+S+
Sbjct: 116 VIARTFTESL 125


>UniRef50_Q6RHV7 Putative uncharacterized protein vs.6 n=1 Tax=Aeromonas phage 65
           RepID=Q6RHV7_9CAUD
          Length = 120

 Score =  101 bits (252), Expect = 1e-19,   Method: Composition-based stats.
 Identities = 47/73 (64%), Positives = 58/73 (79%)

Query: 688 GLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQ 747
            ++         +EGGQHLNVNV+N+E L DA++ PEKYPQLTIRVSGYAVRFNSLT EQ
Sbjct: 48  NMVSVNVEQVPLVEGGQHLNVNVLNKETLEDAIKFPEKYPQLTIRVSGYAVRFNSLTPEQ 107

Query: 748 QQDVITRTFTQSM 760
           Q+DV++RTFT S+
Sbjct: 108 QRDVVSRTFTASL 120


>UniRef50_C0VY69 Putative uncharacterized protein n=1 Tax=Actinomyces coleocanis DSM
           15436 RepID=C0VY69_9ACTO
          Length = 121

 Score =  100 bits (248), Expect = 3e-19,   Method: Composition-based stats.
 Identities = 41/71 (57%), Positives = 51/71 (71%)

Query: 690 MDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQ 749
           M         ++G  H N+NV+N++ L+DAMENPEKYPQLT+RVSGYAV F  LT+EQQ 
Sbjct: 51  MKASRAATGGVKGLYHANINVLNKDTLVDAMENPEKYPQLTVRVSGYAVNFVRLTREQQL 110

Query: 750 DVITRTFTQSM 760
           DVI+RTF   M
Sbjct: 111 DVISRTFHDGM 121


>UniRef50_O94139 Formate C-acetyltransferase (Fragment) n=2 Tax=Piromyces sp. E2
           RepID=O94139_9FUNG
          Length = 140

 Score = 95.9 bits (237), Expect = 5e-18,   Method: Composition-based stats.
 Identities = 28/62 (45%), Positives = 37/62 (59%)

Query: 21  QNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLWDKVMEGVKLENRTHAPVDFDTAVAS 80
           ++E++V  +I+K+YTPYEGD SFLAG TE T  L+ K  E +  E       D D    S
Sbjct: 79  KSEIDVEGWIKKHYTPYEGDGSFLAGPTEKTKKLFAKAEEYLAKERANGGLYDVDPHTPS 138

Query: 81  TI 82
           TI
Sbjct: 139 TI 140


>UniRef50_Q76Z52 Putative uncharacterized protein vs.6 n=1 Tax=Aeromonas phage Aeh1
           RepID=Q76Z52_9CAUD
          Length = 125

 Score = 95.5 bits (236), Expect = 7e-18,   Method: Composition-based stats.
 Identities = 39/66 (59%), Positives = 53/66 (80%)

Query: 695 HHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITR 754
             E+    GQHLNVNV++RE L+ A+E+P +YP L +R+SGYAVRFN+LT EQQ+D++TR
Sbjct: 60  EIESVQHAGQHLNVNVLSREHLMLAIEDPNRYPNLVVRISGYAVRFNALTPEQQRDIVTR 119

Query: 755 TFTQSM 760
           TFT+ M
Sbjct: 120 TFTKHM 125


>UniRef50_C0A3H9 Pyruvate-formate lyase-like protein (Fragment) n=1 Tax=Opitutaceae
           bacterium TAV2 RepID=C0A3H9_9BACT
          Length = 322

 Score = 95.1 bits (235), Expect = 9e-18,   Method: Composition-based stats.
 Identities = 37/210 (17%), Positives = 72/210 (34%), Gaps = 34/210 (16%)

Query: 132 PMIKKIFTEYR-KTHNQGVFDVYTPDILRCR-------KSGVLTGLPDAYGRGRIIGDYR 183
             ++ +   +R +T +  +   +  D+ R           G    L   Y    I  DY+
Sbjct: 114 RHVEDMLDYWRTRTTHAKIRAAHPEDVRRLLPEDNWPNHPGSAFPL---YRIAGITLDYK 170

Query: 184 RVALYGIDYLMKDKLAQFTSLQADLENGVN-----------LEQTIRLREEIAEQHRALG 232
           ++   G+  L+++   Q  +    L    +           LE  + +    A + R L 
Sbjct: 171 KLLRNGLPGLIQNIQRQLAAPPGPLPLPHDAHDLLENTCTVLETLLAIIRRHATEARTLA 230

Query: 233 QM------KEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDV 286
           +         +A         P    +EAIQ  +   LA         +++GR   +L  
Sbjct: 231 RAHPASGAAAIADTLDALTQRPPATLREAIQLAWLASLA------AGVVNYGRMDIWLAP 284

Query: 287 YIERDLKAGKITEQEAQEMVDHLVMKLRMV 316
           +++ DL AG +T   A E +      +   
Sbjct: 285 FLDHDLDAGLLTPDAALEQLKDFWRHIATT 314


>UniRef50_C5EWH7 Putative uncharacterized protein n=2 Tax=Clostridiales bacterium
           1_7_47FAA RepID=C5EWH7_9FIRM
          Length = 499

 Score = 66.6 bits (161), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 82/505 (16%), Positives = 165/505 (32%), Gaps = 119/505 (23%)

Query: 247 GPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMV 306
            P  +  +A+          + +  G A+  G     L+ +++         E EA+   
Sbjct: 87  EPPKDIWDAVGNL-LCLYHNIPADGGLAVYIGCLDRLLEPFVK--------DEDEAR--- 134

Query: 307 DHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGP 366
                  + +RFL T     + +               D     T+     L     M  
Sbjct: 135 -------KAIRFLLTHVDRTISNAF----------CHADLGPEDTRAGRIILELTKEM-Q 176

Query: 367 SPEPNMTILWSEKLPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNNDDYAIACCVSPMIV 426
            P PNMT+++ E  P ++ K A + ++ +S   + ND L R D    DYA+  C + + +
Sbjct: 177 RPCPNMTLMYREDTPDDYMKAALETAMVSSKPSFANDALYRRDM--GDYAVVSCYNTLPI 234

Query: 427 GKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDW 486
           G        R N+            D+  ++   P+    +        V + +D   ++
Sbjct: 235 G-GCGLTLVRLNM------------DQLPRLATDPEDLLNRVIPEAVTAVCDAIDSRCEF 281

Query: 487 LAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVAADSLSAIKYAKVK 546
           +           HY  + + Y   L+   DRD +  M  G  GL+   + +  +   K +
Sbjct: 282 IVD-------YCHYYENTFLYREGLIK-KDRDHMVGM-FGFVGLAECVNGILGLTDEKER 332

Query: 547 PIRDEDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLT 606
                               FG+   + D L   ++ER  ++I +           + + 
Sbjct: 333 --------------------FGHG-EKADALGEAIMERIRQEIDRRPAKYGKYGLHAQVG 371

Query: 607 ITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISY 666
           +       + T +TP GR    P         G + +     +  +       A  G  +
Sbjct: 372 VM------EDTVSTPGGRI---PI--------GEEPELPDQIMNFIRMHKGCDAGCGELF 414

Query: 667 TFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKY 726
                        +     L  ++ G F       G ++L+    + +            
Sbjct: 415 -------PFDDTVKNNPQYLLDILKGAFR-----SGARYLSFYSGDSD------------ 450

Query: 727 PQLTIRVSGYAVRFNSLTKEQQQDV 751
               +RV+GY V+ + + K  + ++
Sbjct: 451 ---LVRVTGYLVKKSDIEKFDRDEM 472


>UniRef50_UPI00017435F3 putative formate acetyltransferase n=1 Tax=candidate division TM7
           single-cell isolate TM7a RepID=UPI00017435F3
          Length = 65

 Score = 65.1 bits (157), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 14/51 (27%), Positives = 18/51 (35%)

Query: 632 PGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVR 682
            G +P  G D  G  A L SV KLP      G        P  +   ++  
Sbjct: 13  EGGSPTQGTDTNGPTAVLNSVNKLPTLMITGGQLLNQKYSPELVNTPEQFE 63


>UniRef50_UPI0001742832 Formate acetyltransferase n=1 Tax=candidate division TM7
          single-cell isolate TM7a RepID=UPI0001742832
          Length = 53

 Score = 62.8 bits (151), Expect = 4e-08,   Method: Composition-based stats.
 Identities = 22/41 (53%), Positives = 28/41 (68%)

Query: 28 DFIQKNYTPYEGDESFLAGATEATTTLWDKVMEGVKLENRT 68
          +FI+ NYT Y GD+SFL G TEATT LW ++ E  K+E   
Sbjct: 1  EFIRLNYTEYLGDDSFLEGPTEATTKLWKELSEKFKVEREK 41


>UniRef50_Q3ADQ8 Putative uncharacterized protein n=1 Tax=Carboxydothermus
           hydrogenoformans Z-2901 RepID=Q3ADQ8_CARHZ
          Length = 511

 Score = 62.0 bits (149), Expect = 8e-08,   Method: Composition-based stats.
 Identities = 33/193 (17%), Positives = 74/193 (38%), Gaps = 30/193 (15%)

Query: 247 GPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMV 306
            P  +  EA+          V S     +  G+    L+ ++   L AG   E+ +++++
Sbjct: 93  KPPQDLFEAVNAL-LIIYRYVPSITSYPVYLGQVDEHLEPFV---LAAG---EELSEKLL 145

Query: 307 DHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGP 366
              ++++  V                 +   +IG          T+     L     +  
Sbjct: 146 KMFLVQIDRVLP-------------DGFVHMNIG-------PKDTRTGRLILKLERELKQ 185

Query: 367 SPEPNMTILWSEKLPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNNDDYAIACCVSPMIV 426
           +  PN+++ ++E+ P +F   A K +++     + ND  ++ D +   Y +A C + +++
Sbjct: 186 AV-PNISLKYNEETPDSFAIEAVKTALEIGKPYFVNDRELKEDLDPA-YGVASCYNTLLI 243

Query: 427 GKQMQFFGARANL 439
           G        R NL
Sbjct: 244 GGGSFTL-VRLNL 255


>UniRef50_C8W8Y4 Putative uncharacterized protein n=3 Tax=Bacteria
           RepID=C8W8Y4_ATOPD
          Length = 500

 Score = 60.8 bits (146), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 64/413 (15%), Positives = 134/413 (32%), Gaps = 106/413 (25%)

Query: 277 FGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWAT 336
            G+    +D ++E       +T+ E         +K R+ RFL   +   + SG      
Sbjct: 110 VGQLDKIIDPFLE------GMTDDE---------IKPRLRRFLNHIDRT-VASGYCH--- 150

Query: 337 ESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEK-LPLNFKKFAAKVSIDT 395
            +IG          T+     L     +  +  PN T+ +  +     F + A K ++  
Sbjct: 151 ANIG-------PEDTRAGRLLLEVERELMNAV-PNFTLKYDPEITSDEFMRLAVKTTMVC 202

Query: 396 SSLQYENDDLMRPDFNNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKL 455
           S+  + N  + +  +  + Y +  C + + +G        R  L      A N  VD+ +
Sbjct: 203 SNPAFANHRIHKETYPGE-YTVVSCYNVLPMGGGAYTLS-RVLLPGLAKLATN--VDDFM 258

Query: 456 KMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALH 515
              +   +           EV+  M+  + ++ +             D   +E S +A  
Sbjct: 259 NNLLPTATS----------EVLNFMNERVRFIVE-------------DSNFFETSFLA-K 294

Query: 516 DRDVIRTMACGIAGLSVAADSLSAIKYAKVKPIRDEDGLAIDFEIEGEYPQFGNNDPRVD 575
           +  + R   CG+ G++  ++ ++ + +                        +G +D    
Sbjct: 295 EGLISRDRFCGMFGVAGMSECVAELLHLDSSRT------------------YGKDDE--- 333

Query: 576 DLAVDLVERFMKKIQKLHTYRDAIPT---QSVLTITSNVVYGKKTGNTPDGR-------- 624
             A +L ++ M KI       DA+ +       T+ +   +  + G TP  R        
Sbjct: 334 --ANELADQIMVKIADQVNSFDAVYSEVFGGRFTLHAQAGFSDQKGVTPGVRIKVGDEPA 391

Query: 625 ----------RAGAPFGPGAN---PMHGRDQKGAVASL---TSVAKLPFAYAK 661
                     R    F  G +   P     ++   A +    +   +   Y  
Sbjct: 392 NLYDHIRHSARMHRFFNSGVSDIFPAEPTAERNPDAVIDVVKAAFSIDDKYLS 444


>UniRef50_Q4C1X2 Putative uncharacterized protein n=1 Tax=Crocosphaera watsonii WH
           8501 RepID=Q4C1X2_CROWT
          Length = 99

 Score = 59.3 bits (142), Expect = 6e-07,   Method: Composition-based stats.
 Identities = 23/58 (39%), Positives = 37/58 (63%), Gaps = 4/58 (6%)

Query: 553 GLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSN 610
           GLA+D+E+E +YP+FGNND R D +   ++  FM  I+K  TYR      ++L+  ++
Sbjct: 5   GLAVDYEVEEDYPKFGNNDERADTITAKVLSDFMNNIRKNKTYRQ----ATLLSPFNH 58


>UniRef50_A5UFY3 Formate acetyltransferase n=1 Tax=Haemophilus influenzae PittGG
          RepID=A5UFY3_HAEIG
          Length = 36

 Score = 57.4 bits (137), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 23/32 (71%), Positives = 23/32 (71%)

Query: 1  MSELNEKLATAWEGFTKGDWQNEVNVRDFIQK 32
          MSELNE    AW GF  GDWQ  VNVRDFIQK
Sbjct: 1  MSELNEMQKLAWAGFAGGDWQENVNVRDFIQK 32


>UniRef50_A6BGV6 Putative uncharacterized protein n=1 Tax=Dorea longicatena DSM
           13814 RepID=A6BGV6_9FIRM
          Length = 43

 Score = 55.4 bits (132), Expect = 8e-06,   Method: Composition-based stats.
 Identities = 13/31 (41%), Positives = 19/31 (61%)

Query: 730 TIRVSGYAVRFNSLTKEQQQDVITRTFTQSM 760
            IRV+GY   F  L K+ Q ++I RT  +S+
Sbjct: 7   LIRVAGYMAYFTELGKDVQDEIIARTEQESL 37


>UniRef50_C3RRJ0 Formate acetyltransferase (Fragment) n=2 Tax=Bacteria
           RepID=C3RRJ0_9MOLU
          Length = 246

 Score = 54.3 bits (129), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 29/172 (16%), Positives = 64/172 (37%), Gaps = 19/172 (11%)

Query: 117 KMIEGSCKAYNRELDPMIKKIFTEYR-KTHNQGVFDVYTPDILRCRKSGVLTGLPD---- 171
           ++ +     ++ E    +++++T +  +   + +   Y  DI                  
Sbjct: 37  RLAKLIEGTHDVE-KEELEELYTFWADENDKERLRRYYPNDIKELMPYDDFENDYYTAYP 95

Query: 172 AYGRGRIIGDYRRVALYGIDYLMK--DKLAQFTSLQADLENGVNLEQTIRLREEIAEQHR 229
            Y  G    D+ ++   GID L+   D     + L+A  ++ + L++ I+L  +      
Sbjct: 96  LYRLGGAYLDFEKLFDLGIDGLIHEIDSQPLNSFLRACKKSLIYLKELIKLYRDDVMDIN 155

Query: 230 ALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTS 281
                 E+A      +     N +EAIQ  +  Y+   + +N     +GR  
Sbjct: 156 P-----ELAYTLNELLEHRPQNMKEAIQLMW-IYVGVSEIRN-----YGRMD 196


>UniRef50_C6Q339 Putative uncharacterized protein n=1 Tax=Clostridium
          carboxidivorans P7 RepID=C6Q339_9CLOT
          Length = 51

 Score = 51.6 bits (122), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 17/38 (44%), Positives = 22/38 (57%)

Query: 32 KNYTPYEGDESFLAGATEATTTLWDKVMEGVKLENRTH 69
          KNYT YEGD+SFL   TE T  +W +  E +  E +  
Sbjct: 13 KNYTAYEGDKSFLEAPTEKTKKIWKEAEELIVEEIKKE 50


>UniRef50_B0PG79 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=B0PG79_9FIRM
          Length = 514

 Score = 50.0 bits (118), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 45/333 (13%), Positives = 97/333 (29%), Gaps = 58/333 (17%)

Query: 237 MAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSF-GRTSTFLDVYIERDLKAG 295
           M     +          EA+                    + GR    L+ +++      
Sbjct: 76  MERGCDFLRLPAPRTLAEALAS--LTIFYTHVPSITHFPVYIGRLDRLLEPFVQA----- 128

Query: 296 KITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIG-GMGLDGRTLVTKNS 354
            +   +A+E +   ++ L  +                 +   +IG    + G        
Sbjct: 129 -VGRAQAREPLRLFLIGLDRII-------------GDSFCHANIGPEQTVTGE------- 167

Query: 355 FRFLNTLYTMGPSPEPNMTILWSEK-LPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNND 413
              +  L  +  +  PN+T+L+     P +F       ++  ++  +  D   R     +
Sbjct: 168 -LIVELLPELQNAV-PNLTLLYDPAVTPDDFAIRCISCALRCANPAFAFDPYYR-ARIGE 224

Query: 414 DYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNY 473
            Y IA C + + VG    F  +R  L K                  GP          + 
Sbjct: 225 QYGIASCYNGLYVGGGA-FSLSRIRLGKIAE------------RCTGPDDFFFNRLPESV 271

Query: 474 DEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVA 533
           D     M+  + ++A++             K ++      LH    +     G+ G++  
Sbjct: 272 DAACRFMEAKIRFIAEE---------IPFFKSNFLVREGFLHRDKFV--GLFGLVGMNEC 320

Query: 534 ADSLSAIKYAKVKPIRDEDGLAIDFEIEGEYPQ 566
            ++L  +     +   DE    +   I     +
Sbjct: 321 VNTLMDLSGDTGRYGPDERANQLGLRIMESIEK 353


>UniRef50_C3RPZ3 Formate C-acetyltransferase n=1 Tax=Mollicutes bacterium D7
           RepID=C3RPZ3_9MOLU
          Length = 166

 Score = 49.7 bits (117), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 25/154 (16%), Positives = 45/154 (29%), Gaps = 15/154 (9%)

Query: 476 VMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVAAD 535
           + ++     D++        N I Y       +     L+             G   + D
Sbjct: 2   LAKQEKFEYDYMNNHCGYLFNSILY---DNCIDRGKSLLNGGIDYLGGTLETYGNVNSGD 58

Query: 536 SLSAIKYAKVKPIR-----DEDGLAIDFEIEGEYP-------QFGNNDPRVDDLAVDLVE 583
           SL AIK               D +  +F    E         ++GN++P VD++  +L +
Sbjct: 59  SLYAIKKLVFDDKEIRYKDMVDAIRNNFIGYEEIREKCLNVIKYGNDNPEVDEMINELNQ 118

Query: 584 RFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKT 617
                 +             V+ I      G  T
Sbjct: 119 YVAVTTKSKSEKYGLSSYLIVIIIKYPFTRGCFT 152


>UniRef50_UPI0001742BAE hypothetical protein cdivTM_20712 n=1 Tax=candidate division TM7
           single-cell isolate TM7a RepID=UPI0001742BAE
          Length = 51

 Score = 46.2 bits (108), Expect = 0.004,   Method: Composition-based stats.
 Identities = 10/36 (27%), Positives = 17/36 (47%)

Query: 312 KLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGR 347
           KL  V  +R+  +    +G P +   +IGG    G+
Sbjct: 11  KLYSVIKVRSTSHSGYGAGYPTYQNVTIGGSTPSGK 46


>UniRef50_UPI0001743618 pyruvate formate-lyase n=1 Tax=candidate division TM7 single-cell
           isolate TM7a RepID=UPI0001743618
          Length = 138

 Score = 46.2 bits (108), Expect = 0.005,   Method: Composition-based stats.
 Identities = 11/63 (17%), Positives = 20/63 (31%), Gaps = 18/63 (28%)

Query: 397 SLQYENDDLMRPDF--------NNDDYAIACCVSPMIVGKQMQFFGARA------NLAKT 442
                 D+++ P          +  +Y++  CV   + GK    +G R       N  K 
Sbjct: 1   MPAMHTDEIIVPALLNKGVKIEDAYNYSMVGCVEVAVPGK----WGYRCTGMTFLNFVKA 56

Query: 443 MLY 445
              
Sbjct: 57  TEL 59


>UniRef50_UPI0001742EA8 hypothetical protein cdivTM_08123 n=1 Tax=candidate division TM7
           single-cell isolate TM7a RepID=UPI0001742EA8
          Length = 50

 Score = 45.0 bits (105), Expect = 0.011,   Method: Composition-based stats.
 Identities = 10/45 (22%), Positives = 17/45 (37%), Gaps = 2/45 (4%)

Query: 436 RANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERM 480
             N  K     +N G D +  +Q+    +    D   YD++ E  
Sbjct: 3   FLNFVKATELVLNDGYDARTGLQLLKAGK--LTDYETYDDLWEAW 45


>UniRef50_UPI0001742D57 hypothetical protein cdivTM_16126 n=1 Tax=candidate division TM7
           single-cell isolate TM7a RepID=UPI0001742D57
          Length = 93

 Score = 43.9 bits (102), Expect = 0.023,   Method: Composition-based stats.
 Identities = 8/32 (25%), Positives = 19/32 (59%)

Query: 557 DFEIEGEYPQFGNNDPRVDDLAVDLVERFMKK 588
           + +I  E P++GN+   VD+ A ++   ++ +
Sbjct: 52  NQKILLEVPKYGNDIDEVDEFATNIYWTYIDR 83


>UniRef50_D2T6G2 Autonomous glycyl radical cofactor n=1 Tax=Erwinia pyrifoliae DSM
           12163 RepID=D2T6G2_ERWPY
          Length = 85

 Score = 43.9 bits (102), Expect = 0.023,   Method: Composition-based stats.
 Identities = 19/39 (48%), Positives = 28/39 (71%)

Query: 696 HEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVS 734
           +   + GGQHLN N ++RE L + +++PE  PQLT+RVS
Sbjct: 35  YRLRVAGGQHLNANFLSREGLEEVVKHPEITPQLTLRVS 73


Searching..................................................done


Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_Q2G1D8 Formate acetyltransferase n=978 Tax=cellular org...   827   0.0  
UniRef50_A0Q2M5 Pyruvate formate-lyase n=9 Tax=Bacteria RepID=A0...   737   0.0  
UniRef50_B2TMN7 Formate C-acetyltransferase n=13 Tax=Bacteria Re...   734   0.0  
UniRef50_B3DSM0 Pyruvate-formate lyase n=32 Tax=Bacteria RepID=B...   721   0.0  
UniRef50_C6VIV4 Formate C-acetyltransferase n=25 Tax=Bacteria Re...   687   0.0  
UniRef50_B2TJX0 Formate C-acetyltransferase n=9 Tax=Bacteria Rep...   686   0.0  
UniRef50_P75793 Putative formate acetyltransferase 3 n=109 Tax=B...   682   0.0  
UniRef50_D1AFQ7 Pyruvate formate-lyase n=3 Tax=Fusobacteriaceae ...   679   0.0  
UniRef50_A6LQ73 Pyruvate formate-lyase n=6 Tax=Bacteria RepID=A6...   672   0.0  
UniRef50_B1C5P6 Putative uncharacterized protein n=3 Tax=Bacteri...   668   0.0  
UniRef50_A8GF53 Pyruvate formate-lyase n=31 Tax=Bacteria RepID=A...   668   0.0  
UniRef50_B2ISH7 Formate acetyltransferase, putative n=59 Tax=Bac...   666   0.0  
UniRef50_B8G188 Pyruvate formate-lyase n=1 Tax=Desulfitobacteriu...   663   0.0  
UniRef50_Q18AX8 Glycerol dehydratase n=8 Tax=Clostridium RepID=Q...   658   0.0  
UniRef50_Q1A666 Glycerol dehydratase n=8 Tax=Clostridiales RepID...   655   0.0  
UniRef50_C7X781 Pyruvate formate-lyase n=3 Tax=Bacteroidales Rep...   655   0.0  
UniRef50_P32674 Formate acetyltransferase 2 n=80 Tax=Gammaproteo...   652   0.0  
UniRef50_B6FX97 Putative uncharacterized protein n=4 Tax=Firmicu...   651   0.0  
UniRef50_C6A251 Pyruvate-formate lyase n=50 Tax=cellular organis...   645   0.0  
UniRef50_B5XXR3 Formate C-acetyltransferase 2 n=9 Tax=cellular o...   645   0.0  
UniRef50_B4U135 Pyruvate formate-lyase n=65 Tax=Bacilli RepID=B4...   642   0.0  
UniRef50_B6FJR9 Putative uncharacterized protein n=1 Tax=Clostri...   641   0.0  
UniRef50_A6TKL5 Pyruvate formate-lyase n=1 Tax=Alkaliphilus meta...   641   0.0  
UniRef50_A6TPN1 Formate C-acetyltransferase n=3 Tax=Clostridiace...   638   0.0  
UniRef50_O28823 Pyruvate formate-lyase 2 (PflD) n=1 Tax=Archaeog...   637   0.0  
UniRef50_A8ZW07 Formate C-acetyltransferase n=2 Tax=Proteobacter...   635   e-180
UniRef50_C1N297 Predicted protein n=1 Tax=Micromonas pusilla CCM...   632   e-179
UniRef50_D1ARQ1 Pyruvate formate-lyase n=3 Tax=Bacteria RepID=D1...   632   e-179
UniRef50_C0QGR8 PflD1 n=1 Tax=Desulfobacterium autotrophicum HRM...   630   e-179
UniRef50_O32799 Formate acetyltransferase n=32 Tax=Bacilli RepID...   627   e-178
UniRef50_C7N778 Pyruvate-formate lyase n=1 Tax=Slackia heliotrin...   625   e-177
UniRef50_B8FFL2 Formate C-acetyltransferase n=1 Tax=Desulfatibac...   623   e-177
UniRef50_A5N4Z6 Predicted glycyl radical enzyme n=2 Tax=Clostrid...   616   e-174
UniRef50_A8MJE8 Formate C-acetyltransferase n=57 Tax=Bacteria Re...   613   e-173
UniRef50_C0W9F6 Formate C-acetyltransferase n=1 Tax=Acidaminococ...   611   e-173
UniRef50_B8FA81 Formate C-acetyltransferase n=1 Tax=Desulfatibac...   603   e-171
UniRef50_C0C5J5 Putative uncharacterized protein n=1 Tax=Clostri...   603   e-170
UniRef50_Q312S2 Formate C-acetyltransferase n=9 Tax=Bacteria Rep...   598   e-169
UniRef50_A6CWD5 Formate acetyltransferase 2 n=4 Tax=Bacteria Rep...   591   e-167
UniRef50_B0G487 Putative uncharacterized protein n=2 Tax=Clostri...   582   e-164
UniRef50_C6BT93 Formate C-acetyltransferase n=6 Tax=Desulfovibri...   578   e-163
UniRef50_B8J0R1 Formate C-acetyltransferase n=9 Tax=Proteobacter...   575   e-162
UniRef50_B8FDB2 Formate C-acetyltransferase n=1 Tax=Desulfatibac...   568   e-160
UniRef50_Q30WU7 Formate C-acetyltransferase n=1 Tax=Desulfovibri...   565   e-159
UniRef50_D2LJ70 Formate C-acetyltransferase n=1 Tax=Rhodomicrobi...   561   e-158
UniRef50_B1BA70 HpdB protein n=1 Tax=Clostridium botulinum C str...   553   e-156
UniRef50_A6G8C6 Pyruvate formate-lyase 2 (PflD) n=1 Tax=Plesiocy...   551   e-155
UniRef50_B8FHW6 Formate C-acetyltransferase n=2 Tax=Desulfobacte...   543   e-153
UniRef50_A5CZF4 Pyruvate-formate lyase n=1 Tax=Pelotomaculum the...   540   e-152
UniRef50_B5I3J0 Truncated formate acetyltransferase n=8 Tax=Bact...   531   e-149
UniRef50_B8FEM4 Formate C-acetyltransferase n=5 Tax=Proteobacter...   509   e-142
UniRef50_B0CLU5 Alpha-subunit of naphtylmethylsuccinate synthase...   509   e-142
UniRef50_B8FMK7 Formate C-acetyltransferase n=1 Tax=Desulfatibac...   502   e-140
UniRef50_UPI00016BFDA6 pyruvate formate-lyase n=1 Tax=Epulopisci...   496   e-138
UniRef50_Q38HX4 4-hydroxyphenylacetate decarboxylase glycyl radi...   495   e-138
UniRef50_B2V300 4-hydroxyphenylacetate decarboxylase, catalytic ...   492   e-137
UniRef50_B0MIH0 Putative uncharacterized protein n=1 Tax=Anaeros...   487   e-136
UniRef50_Q39VF1 Formate C-acetyltransferase glycine radical:Pyru...   483   e-134
UniRef50_C5EHI0 Pyruvate formate-lyase n=8 Tax=Bacteria RepID=C5...   477   e-133
UniRef50_A9KN53 Pyruvate formate-lyase n=21 Tax=Bacteria RepID=A...   468   e-130
UniRef50_D1ANR4 Formate C-acetyltransferase n=1 Tax=Sebaldella t...   467   e-130
UniRef50_A5ZSK3 Putative uncharacterized protein n=1 Tax=Ruminoc...   437   e-121
UniRef50_A6CVH9 Formate C-acetyltransferase n=10 Tax=Bacteria Re...   436   e-120
UniRef50_D1NB06 Formate C-acetyltransferase n=1 Tax=Victivallis ...   432   e-119
UniRef50_C0CUZ2 Putative uncharacterized protein n=1 Tax=Clostri...   431   e-119
UniRef50_A7VPJ9 Putative uncharacterized protein n=1 Tax=Clostri...   421   e-116
UniRef50_B0NGB8 Putative uncharacterized protein n=3 Tax=Bacteri...   409   e-112
UniRef50_D1N5W4 Formate C-acetyltransferase n=1 Tax=Victivallis ...   405   e-111
UniRef50_C7ILA9 Formate C-acetyltransferase n=1 Tax=Clostridium ...   404   e-111
UniRef50_B9M4R7 Formate C-acetyltransferase n=2 Tax=Bacteria Rep...   403   e-110
UniRef50_D1N9D9 Formate C-acetyltransferase n=1 Tax=Victivallis ...   402   e-110
UniRef50_D1N4L3 Formate C-acetyltransferase n=1 Tax=Victivallis ...   401   e-110
UniRef50_C3Z558 Putative uncharacterized protein n=3 Tax=Branchi...   401   e-110
UniRef50_D0RZP3 Formate acetyltransferase n=1 Tax=Acinetobacter ...   398   e-109
UniRef50_C5V5J7 Formate C-acetyltransferase n=1 Tax=Gallionella ...   397   e-108
UniRef50_Q2HBR9 Putative uncharacterized protein n=1 Tax=Chaetom...   392   e-107
UniRef50_A7VW43 Putative uncharacterized protein n=1 Tax=Clostri...   386   e-105
UniRef50_O26446 Formate acetyltransferase 2 n=1 Tax=Methanotherm...   383   e-104
UniRef50_C6IIV1 Formate acetyltransferase 2 n=3 Tax=Bacteria Rep...   378   e-103
UniRef50_Q24T37 Putative pyruvate-formate lyase n=1 Tax=Desulfit...   378   e-103
UniRef50_C7XCZ5 Formate acetyltransferase 2 n=2 Tax=Bacteria Rep...   366   1e-99
UniRef50_C0A3H6 Formate C-acetyltransferase n=1 Tax=Opitutaceae ...   351   6e-95
UniRef50_A3RV69 Formate acetyltransferase n=5 Tax=Ralstonia sola...   338   6e-91
UniRef50_Q2C4S5 Formate acetyltransferase n=7 Tax=Gammaproteobac...   309   2e-82
UniRef50_UPI0001C3572E putative pyruvate-formate lyase n=1 Tax=C...   249   3e-64
UniRef50_UPI0001C420E7 pyruvate-formate lyase Pfl n=1 Tax=Methan...   245   4e-63
UniRef50_UPI00019247E5 PREDICTED: hypothetical protein, partial ...   240   1e-61
UniRef50_C5EWH7 Putative uncharacterized protein n=2 Tax=Clostri...   174   2e-41
UniRef50_O94132 Formate C-acetyltransferase (Fragment) n=2 Tax=P...   170   1e-40
UniRef50_D1NCN8 Formate C-acetyltransferase n=1 Tax=Haemophilus ...   160   1e-37
UniRef50_B7BHI6 Putative uncharacterized protein (Fragment) n=1 ...   143   2e-32
UniRef50_Q7NEY2 Glr3745 protein n=1 Tax=Gloeobacter violaceus Re...   142   7e-32
UniRef50_B0PG79 Putative uncharacterized protein n=2 Tax=Clostri...   128   6e-28
UniRef50_C8W8Y4 Putative uncharacterized protein n=3 Tax=Bacteri...   123   2e-26
UniRef50_B1EF41 Keto-acid formate acetyltransferase (Keto-acid f...   122   4e-26
UniRef50_A6BGV7 Putative uncharacterized protein n=1 Tax=Dorea l...   118   9e-25
UniRef50_C0A3H9 Pyruvate-formate lyase-like protein (Fragment) n...   116   4e-24
UniRef50_Q3ADQ8 Putative uncharacterized protein n=1 Tax=Carboxy...   104   1e-20
UniRef50_B7UH18 Autonomous glycyl radical cofactor n=257 Tax=roo...   103   4e-20
UniRef50_Q70BJ5 Putative uncharacterized protein n=4 Tax=Siphovi...   100   2e-19
UniRef50_Q5E2Y6 Autonomous glycyl radical cofactor n=6 Tax=Prote...    99   5e-19
UniRef50_Q6RHV7 Putative uncharacterized protein vs.6 n=1 Tax=Ae...    99   6e-19
UniRef50_Q56EP5 Vs.6 n=5 Tax=unclassified T4-like viruses RepID=...    99   9e-19
UniRef50_C0VY69 Putative uncharacterized protein n=1 Tax=Actinom...    98   1e-18
UniRef50_O94139 Formate C-acetyltransferase (Fragment) n=2 Tax=P...    92   7e-17
UniRef50_Q76Z52 Putative uncharacterized protein vs.6 n=1 Tax=Ae...    89   7e-16
UniRef50_C3RPZ3 Formate C-acetyltransferase n=1 Tax=Mollicutes b...    86   4e-15
UniRef50_C3RRJ0 Formate acetyltransferase (Fragment) n=2 Tax=Bac...    81   2e-13
UniRef50_UPI00017435F3 putative formate acetyltransferase n=1 Ta...    65   9e-09
UniRef50_UPI0001742832 Formate acetyltransferase n=1 Tax=candida...    63   3e-08
UniRef50_A5UFY3 Formate acetyltransferase n=1 Tax=Haemophilus in...    55   8e-06
UniRef50_C6Q339 Putative uncharacterized protein n=1 Tax=Clostri...    55   1e-05
UniRef50_A6BGV6 Putative uncharacterized protein n=1 Tax=Dorea l...    54   2e-05
UniRef50_Q4C1X2 Putative uncharacterized protein n=1 Tax=Crocosp...    53   3e-05

Sequences not found previously or not previously below threshold:

UniRef50_B9Y9Q5 Putative uncharacterized protein n=1 Tax=Holdema...   115   5e-24
UniRef50_A1SHU8 Putative uncharacterized protein n=1 Tax=Nocardi...   108   1e-21
UniRef50_A3DFS4 Putative uncharacterized protein n=22 Tax=Clostr...   103   3e-20
UniRef50_D1AIQ0 Putative uncharacterized protein n=4 Tax=Bacteri...    97   3e-18
UniRef50_P37342 Uncharacterized protein yjjI n=153 Tax=Proteobac...    89   6e-16
UniRef50_UPI0001C361F0 hypothetical protein ChatD1_32948 n=2 Tax...    88   2e-15
UniRef50_P44744 Uncharacterized protein HI0521 n=23 Tax=Bacteria...    80   4e-13
UniRef50_UPI0001743618 pyruvate formate-lyase n=1 Tax=candidate ...    55   1e-05
UniRef50_UPI0001742EA8 hypothetical protein cdivTM_08123 n=1 Tax...    46   0.007
UniRef50_UPI00017437D2 hypothetical protein cdivTM_13064 n=1 Tax...    45   0.015
UniRef50_UPI0001742BAE hypothetical protein cdivTM_20712 n=1 Tax...    44   0.027
UniRef50_C0D5P2 Putative uncharacterized protein (Fragment) n=1 ...    43   0.030
UniRef50_UPI0001742AB8 putative formate acetyltransferase 3 n=1 ...    43   0.052

>UniRef50_Q2G1D8 Formate acetyltransferase n=978 Tax=cellular organisms
           RepID=PFLB_STAA8
          Length = 749

 Score =  827 bits (2137), Expect = 0.0,   Method: Composition-based stats.
 Identities = 503/760 (66%), Positives = 614/760 (80%), Gaps = 11/760 (1%)

Query: 1   MSELNEKLATAWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLWDKVME 60
           M E N+  ATAW+GF  G W   V+VR+FIQ NYT YEG++SFLAG TEAT+ LW++VM+
Sbjct: 1   MLETNKNHATAWQGFKNGRWNRHVDVREFIQLNYTLYEGNDSFLAGPTEATSKLWEQVMQ 60

Query: 61  GVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIKMIE 120
             K E       D DT VASTITSHDAGY++K LE IVG+QTE P KR++ PFGGI+M +
Sbjct: 61  LSKEERERGGMWDMDTKVASTITSHDAGYLDKDLETIVGVQTEKPFKRSMQPFGGIRMAK 120

Query: 121 GSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIG 180
            +C+AY  ELD   +KIFT+YRKTHNQGVFD Y+ ++L CRK+GV+TGLPDAYGRGRIIG
Sbjct: 121 AACEAYGYELDEETEKIFTDYRKTHNQGVFDAYSREMLNCRKAGVITGLPDAYGRGRIIG 180

Query: 181 DYRRVALYGIDYLMKDKLAQFTSLQADLENGVNLEQTIRLREEIAEQHRALGQMKEMAAK 240
           DYRRVALYG+D+LM++K+  F ++  ++      E  IRLREE++EQ+RAL ++KE+  K
Sbjct: 181 DYRRVALYGVDFLMEEKMHDFNTMSTEMS-----EDVIRLREELSEQYRALKELKELGQK 235

Query: 241 YGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQ 300
           YG+D+S PA N +EA+QW Y  YLAA+K QNGAAMS GRTSTFLD+Y ERDLKAG ITE 
Sbjct: 236 YGFDLSRPAENFKEAVQWLYLAYLAAIKEQNGAAMSLGRTSTFLDIYAERDLKAGVITES 295

Query: 301 EAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNT 360
           E QE++DH +MKLR+V+F RTP+Y+ELFSGDP W TESIGG+G+DGR LVTKNSFRFL++
Sbjct: 296 EVQEIIDHFIMKLRIVKFARTPDYNELFSGDPTWVTESIGGVGIDGRPLVTKNSFRFLHS 355

Query: 361 LYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNNDDYAIACC 420
           L  +GP+PEPN+T+LWS +LP NFK + AK+SI TSS+QYENDD+MR  +  DDY IACC
Sbjct: 356 LDNLGPAPEPNLTVLWSVRLPDNFKTYCAKMSIKTSSIQYENDDIMRESY-GDDYGIACC 414

Query: 421 VSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERM 480
           VS M +GKQMQFFGARANLAKT+LYAINGG DEK   QVGP  E I  +VL YDEV ++ 
Sbjct: 415 VSAMTIGKQMQFFGARANLAKTLLYAINGGKDEKSGAQVGPNFEGINSEVLEYDEVFKKF 474

Query: 481 DHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVAADSLSAI 540
           D  MDWLA  YI +LN+IHYMHDKYSYE   MALHD +++RTMA GIAGLSVAADSLSAI
Sbjct: 475 DQMMDWLAGVYINSLNVIHYMHDKYSYERIEMALHDTEIVRTMATGIAGLSVAADSLSAI 534

Query: 541 KYAKVKPIRDEDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIP 600
           KYA+VKPIR+E+GL +DFEIEG++P++GNND RVDD+AVDLVERFM K++   TYRD+  
Sbjct: 535 KYAQVKPIRNEEGLVVDFEIEGDFPKYGNNDDRVDDIAVDLVERFMTKLRSHKTYRDSEH 594

Query: 601 TQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYA 660
           T SVLTITSNVVYGKKTGNTPDGR+AG PF PGANPMHGRDQKGA++SL+SVAK+P+   
Sbjct: 595 TMSVLTITSNVVYGKKTGNTPDGRKAGEPFAPGANPMHGRDQKGALSSLSSVAKIPYDCC 654

Query: 661 KDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAM 720
           KDGIS TFSIVP +LGK+ E +  NL  ++DGY     +++ G HLN+NV NRE L+DAM
Sbjct: 655 KDGISNTFSIVPKSLGKEPEDQNRNLTSMLDGY-----AMQCGHHLNINVFNRETLIDAM 709

Query: 721 ENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQSM 760
           E+PE+YPQLTIRVSGYAV F  LT+EQQ DVI+RTF +SM
Sbjct: 710 EHPEEYPQLTIRVSGYAVNFIKLTREQQLDVISRTFHESM 749


>UniRef50_A0Q2M5 Pyruvate formate-lyase n=9 Tax=Bacteria RepID=A0Q2M5_CLONN
          Length = 803

 Score =  737 bits (1902), Expect = 0.0,   Method: Composition-based stats.
 Identities = 180/779 (23%), Positives = 314/779 (40%), Gaps = 91/779 (11%)

Query: 58  VMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIK 117
           + E  K        +         I  ++   + ++ E IVG  T+      + P    K
Sbjct: 37  LTESFKETENQPIII-RKAKALEKIL-NEMPIVIREGELIVGSLTKNSRSAQVFPEFSNK 94

Query: 118 M-IEGSCKAYNRELDPM---------IKKIFTEYR-KTHNQGVFDVYTPDILRCRKSGVL 166
             +E   K   R  D           +  IF  +  KT ++        + L    + V 
Sbjct: 95  WLVEEFEKLPKRTSDSFQISEEVKSELIDIFKYWEGKTVSELATSYMPKETLEAMGAKVF 154

Query: 167 TGLPDAY-GRGRIIGDYRRVALYGIDYLMKD-----------------KLAQFTSLQADL 208
           T     + G G I  DY++V   G   ++++                 K   + ++    
Sbjct: 155 TVANYYFNGLGHISVDYKKVLELGFKGIIEEIKAKMDSADKSDPEYIKKRTFWEAVIISC 214

Query: 209 ENGV-NLEQTIRLREEIAEQH---RALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYL 264
           E  +    +  +L +E++E     +   ++ ++A         PAT   EA Q  +F   
Sbjct: 215 EAAIDYARRYAKLAKELSENTEDCKRKEELLKIAEICSKVPENPATTFYEACQSFWFVQA 274

Query: 265 AAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEY 324
                 NG A+S  R   ++  Y + D+    +T++E +E++  L +K   +  +R    
Sbjct: 275 IISLESNGHAISPARFDQYMYPYFKSDVDNNVVTKEENREILQCLWVKFNDLTKVRDETT 334

Query: 325 DELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNF 384
            + FSG  ++    +GG   +G+    + S+  L+   ++   P+P++++    K P  F
Sbjct: 335 TKAFSGYSMFQNLIVGGQTEEGKDATNELSYMCLDATGSL-KLPQPSLSVRIWSKTPEEF 393

Query: 385 KKFAAKVSI-DTSSLQYENDDLMRPDF--------NNDDYAIACCVSPMIVGKQMQFFG- 434
                +++   T    + ND+++ P          +  DYAI  CV P   GK   ++  
Sbjct: 394 LIRTCELTRLGTGLPAFYNDEVIIPMLVNNGMTLEDARDYAIVGCVEPQKPGKTDGWYDA 453

Query: 435 ARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITA 494
           A  NLA+ +   I+ G       QVGPK+   + +  + DEV+E     M++   Q ++A
Sbjct: 454 AFFNLAQILKLTIDNGK--MDGKQVGPKTGEFE-EFKDIDEVIEAYKKQMEYFVAQMVSA 510

Query: 495 LNIIHYMHDKYSYEASLMALHDRDVIRTMACG------------IAGLSVAADSLSAIKY 542
            N +   H + +    L A+ D  + +  +                G++   DS  AIK 
Sbjct: 511 DNCVDIAHRERAPLPFLSAMLDDCIAKGKSIQEGGGHYRFSGPLGVGIANVGDSFMAIKK 570

Query: 543 AKVKP---IRDEDGLAIDFEI--------------------EGEYPQFGNNDPRVDDLAV 579
                     D+   A+D                           P+FGN+   VD+   
Sbjct: 571 LVFDDEKITLDKLKQALDGNFGKDEKDEGKKNELQGIKQMLLHRAPKFGNDIDEVDEFTR 630

Query: 580 DLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHG 639
           +    +  ++ K    R       +  +++NV  G   G TPDGR A  P   G +P  G
Sbjct: 631 EGALIYCNEVLKHFNQRGGKFLPGLYPVSNNVHLGSLVGATPDGREAYQPIADGVSPTRG 690

Query: 640 RDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEAS 699
            D  G  A+  SVAKL    A  G  +     P++L  D+ +R  NL  L+  YF H+  
Sbjct: 691 ADVNGPTAAANSVAKLEHYAAPSGTLFNQKFNPSSLKGDNGLR--NLGTLIRSYFDHK-- 746

Query: 700 IEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQ 758
              G H+  NV+++ +LLDA ++PEKY  L +RV+GY+ +F  L KE Q D+I RT  +
Sbjct: 747 ---GMHIQFNVVDKNVLLDAQKHPEKYRDLIVRVAGYSAQFICLNKEIQDDIIKRTEQE 802


>UniRef50_B2TMN7 Formate C-acetyltransferase n=13 Tax=Bacteria RepID=B2TMN7_CLOBB
          Length = 803

 Score =  734 bits (1896), Expect = 0.0,   Method: Composition-based stats.
 Identities = 169/779 (21%), Positives = 301/779 (38%), Gaps = 91/779 (11%)

Query: 58  VMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIK 117
           + E  K        +         I S +   + +  E IVG  T+ P    + P    +
Sbjct: 37  LTESFKETENEPIII-RKAKSLEKILS-EIPVVIRDNELIVGSLTKNPRSCQVFPEFSNQ 94

Query: 118 M-IEGSCKAYNRELDPM---------IKKIFTEYR-KTHNQGVFDVYTPDILRCRKSGVL 166
             ++   K   R  D           +K++F  ++ KT ++      + +      + V 
Sbjct: 95  WLVDEFDKFEKRTSDLFKIPEETKSKLKEVFKYWQGKTVSELATSYMSNETKDAMNTKVF 154

Query: 167 TGLPDAY-GRGRIIGDYRRVALYGIDYLMKD-----------------KLAQFTSLQADL 208
           T     + G G I  DY +V   G   ++K+                 K   + S+    
Sbjct: 155 TVANYHFNGLGHISVDYPKVLEKGFLGIIKETENAIINADKSNPEYVKKKVFWDSIIISC 214

Query: 209 ENGV-NLEQTIRLREEIAEQH---RALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYL 264
           +  +    +   L +++A +        ++ ++A       + PA    EA Q  +F   
Sbjct: 215 KAAIKYANRYSELAKKLAGETLDINRKNELLKIAEICSKVPANPAETFYEACQSFWFVQA 274

Query: 265 AAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEY 324
                 NG A+S  R   ++  Y + D+     T++   E++  L +K   +  +R    
Sbjct: 275 IISLESNGHAISPARFDQYMYPYYKNDIDNKFATKEVNTEILHCLWVKFNDLTKVRDETT 334

Query: 325 DELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNF 384
            + FSG  ++    +GG   DG+    + S+  L    ++   P+P++ +    K P  F
Sbjct: 335 TKAFSGYSMFQNLIVGGQTPDGKDATNELSYMCLEATGSL-KLPQPSLCVRIWSKTPDEF 393

Query: 385 KKFAAKVSI-DTSSLQYENDDLMRPDF--------NNDDYAIACCVSPMIVGKQMQFFG- 434
                +++   T    + ND+++ P          +  DYAI  CV P   GK   ++  
Sbjct: 394 LIRTCELTRLGTGLPAFYNDEVVIPTLINQGLTIEDARDYAIVGCVEPQKPGKTDGWYDA 453

Query: 435 ARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITA 494
           A  NLAK +  ++N G       QVGP++        N D+ +      +++     + A
Sbjct: 454 AFFNLAKILELSMNNG--RLNGRQVGPETGEFTS-FKNIDDFINAYKKQIEYFVFHMVAA 510

Query: 495 LNIIHYMHDKYSYEASLMALHDRDVIRTMACG------------IAGLSVAADSLSAIKY 542
            N +   H + +    L ++ D  +    +                G++   DS  AIK 
Sbjct: 511 DNCVDIAHAERAPLPFLSSMLDDCIGTGKSIQEGGGHYRFSGPLGVGIANVGDSFMAIKK 570

Query: 543 AKV---KPIRDEDGLAIDFEI--------------------EGEYPQFGNNDPRVDDLAV 579
                 K    +   A+D                           P+FGN+   VD+   
Sbjct: 571 LIFDENKITLLKLKSAVDSNFGENEDDPIKKAEYEDIKQLILNRVPKFGNDIDEVDEFTR 630

Query: 580 DLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHG 639
           D    + K++ K    R       +  +++NV  G   G TPDGR A  P   G +P  G
Sbjct: 631 DGALIYCKEVLKYTNQRGGKFIPGLYPVSNNVYLGSLVGATPDGRSAFKPLADGVSPTRG 690

Query: 640 RDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEAS 699
            D  G  A+  SV+KL    A  G  +     PN+L  D+ ++  NL  L+  YF     
Sbjct: 691 ADVNGPTAAANSVSKLEHFAAPSGTLFNQKFNPNSLQGDNGLK--NLGSLIRSYFD---- 744

Query: 700 IEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQ 758
              G H+  NV+++++L++A ++PE+Y  L +RV+GY+ +F  L K  Q D+I RT   
Sbjct: 745 -RKGMHIQFNVIDKKVLVEAQKHPEQYRDLIVRVAGYSAQFICLDKGVQDDIIKRTEQN 802


>UniRef50_B3DSM0 Pyruvate-formate lyase n=32 Tax=Bacteria RepID=B3DSM0_BIFLD
          Length = 791

 Score =  721 bits (1861), Expect = 0.0,   Method: Composition-based stats.
 Identities = 417/783 (53%), Positives = 536/783 (68%), Gaps = 35/783 (4%)

Query: 5   NEKLATAWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLWDKVMEGVKL 64
            E  A AW GFT+G+WQ +++VRDFIQKNYTPYEGDE+FLA ATE T  LW  + +    
Sbjct: 12  EELDAKAWAGFTEGNWQKDIDVRDFIQKNYTPYEGDETFLAPATEKTKHLWKYLDDNYLA 71

Query: 65  ENRTHAPVDFDTAVASTITSHDAGYINKQ--LEKIVGLQTEAPLKRALIPFGGIKMIEGS 122
             R     D DT   + + +  AGYI+       +VGLQT+ P KRA++P GG +M+E +
Sbjct: 72  VERKQRVYDVDTHTPADVDAFPAGYIDSPEVDNVVVGLQTDVPCKRAMMPNGGWRMVEQA 131

Query: 123 CKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDY 182
            K   +E DP IKKIFT+YRKTHN GVF VYT  I   R + +LTGLPDAYGRGRIIGDY
Sbjct: 132 IKEAGKEPDPEIKKIFTKYRKTHNDGVFGVYTKQIKVARHNKILTGLPDAYGRGRIIGDY 191

Query: 183 RRVALYGIDYLM--KDKLAQFTSLQADLENGVNLEQTIRLREEIAEQHRALGQMKEMAAK 240
           RRVALYG++ L+  K +       + D      +E  IR REE  EQ +AL ++  +  +
Sbjct: 192 RRVALYGVNKLIAFKKRDKDSVPYRNDF-TEPEIEHWIRFREEHDEQIKALKKLINLGNE 250

Query: 241 YGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQ 300
           YG D+S PA  AQEA+QWTY GYLA++KSQ+GAAMSFGR S FLD YIERDL+AGKITE 
Sbjct: 251 YGLDLSRPAQTAQEAVQWTYMGYLASIKSQDGAAMSFGRNSAFLDCYIERDLQAGKITET 310

Query: 301 EAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLN- 359
           +AQE++D++VMKLR+VRFLRT +YD +FSGDP WAT S  G G DGR++VTK SFR LN 
Sbjct: 311 DAQELIDNIVMKLRIVRFLRTKDYDSIFSGDPYWATWSDAGFGDDGRSMVTKTSFRLLNT 370

Query: 360 -TLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNNDDYAIA 418
            TL  +GP PEPN+TI W  KLP  +K+F AK+SIDTS++QYE+D  +R  +  DD AIA
Sbjct: 371 LTLEHLGPGPEPNITIFWDPKLPEAYKRFCAKISIDTSAIQYESDKEIRSHW-GDDAAIA 429

Query: 419 CCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPK-----SEPIKGDVLNY 473
           CCVSPM VGKQMQFF AR N AK +LYAINGG DE   MQV  K       P     L+Y
Sbjct: 430 CCVSPMRVGKQMQFFAARVNSAKALLYAINGGRDEMTGMQVIDKGVIEPITPEADGTLDY 489

Query: 474 DEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVA 533
           ++V    +  ++WL++ Y+ ALNIIHYMHDKY+YE+  MALHD++V RT+ CG++GLS+A
Sbjct: 490 EKVKNNYEKALEWLSETYVMALNIIHYMHDKYAYESIEMALHDKEVYRTLGCGMSGLSIA 549

Query: 534 ADSLSAIKYAKVKPIRDEDGLAID-----------------FEIEGEYPQFGNNDPRVDD 576
           ADSL+A+KYAKV PI ++D   ++                 +  EGE+P +GN+D R DD
Sbjct: 550 ADSLAAVKYAKVYPIYNKDAKTLEGHEYEYVEGADDDLIVGYRTEGEFPVYGNDDDRADD 609

Query: 577 LAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANP 636
           +A  +V   M ++++L  YR A+PTQS+LTITSNV YGK TG+ P G   G P+ PGANP
Sbjct: 610 IAKWVVSTVMGQVKRLPVYRGAVPTQSILTITSNVEYGKNTGSFPSGHAKGTPYAPGANP 669

Query: 637 MHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHH 696
            +G D  G + S+ SV K+ +  A DGIS T +I P+ LG+D++ R  NL G++D     
Sbjct: 670 ENGMDSHGMLPSMFSVGKIDYNDALDGISLTNTITPDGLGRDEDERIGNLVGILDA---- 725

Query: 697 EASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTF 756
             +  G  H N+NV+ +E + DA+E+PEKYP LT+RVSGYAV F  LTKEQQ DVI+RTF
Sbjct: 726 -GNGHGLYHANINVLRKETMEDAVEHPEKYPHLTVRVSGYAVNFVKLTKEQQLDVISRTF 784

Query: 757 TQS 759
            Q 
Sbjct: 785 HQG 787


>UniRef50_C6VIV4 Formate C-acetyltransferase n=25 Tax=Bacteria RepID=C6VIV4_LACPJ
          Length = 814

 Score =  687 bits (1773), Expect = 0.0,   Method: Composition-based stats.
 Identities = 174/777 (22%), Positives = 306/777 (39%), Gaps = 87/777 (11%)

Query: 59  MEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIKM 118
            E  +        +     +   +    + +I      IVG Q        + P   +  
Sbjct: 47  TETYRQHQDEQVDI-LRAKMLEHVLDKMSIFIE-DDTLIVGNQARQNRWAPVFPEYSMNW 104

Query: 119 -IEGSCKAYNRELDPMI---------KKIFTEYR-KTHNQGVFDVYTPDILRCRKSGVLT 167
            I+       R  D            + I   ++  T     +  +          G++ 
Sbjct: 105 VIDELDTFEKRPGDVFYITEKSKEELRAIAPFWKHNTLEDRGYASFPEASRIFYDLGIIG 164

Query: 168 GLPDA-YGRGRIIGDYRRVALYGI---DYLMKDKLAQFTSLQADLENGVN---------- 213
              +   G G I  DY+ V   G+   +  +K  LA       + +              
Sbjct: 165 ADGNITSGDGHIAVDYKNVVNKGLKWYEDRIKTALANLDLTDFNQQKQYYFYKAGLIVID 224

Query: 214 -----LEQTIRLREEIAEQ---HRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLA 265
                 ++  +L  + A+         Q++++A         PA +  EAIQ  +  +L 
Sbjct: 225 AIHNFAKRYAQLASKQAQNTTSATRKAQLEKIAQILNKVPYEPANSFYEAIQAVWLVHLT 284

Query: 266 AVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYD 325
                NG ++S+GR   +LD + E DLK G I    A E++ +L +K   +  +R+ ++ 
Sbjct: 285 LQIESNGHSVSYGRLDQYLDPFYEHDLKTGAIDANGATELLTNLCLKTLTINKVRSWQHT 344

Query: 326 ELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFK 385
           E  +G P++   +IGG   DG+  V   S+  L  +      P+PN+T+ +   L   F 
Sbjct: 345 EFSAGSPLYQNITIGGQTPDGKDAVNPTSYLILRAIAQ-AHLPQPNLTVRYHHGLSDKFM 403

Query: 386 KFAAK-VSIDTSSLQYENDDLMRPDF--------NNDDYAIACCVSPMIVGK-QMQFFG- 434
           +   + +        + ND+++ P F        +  +Y+   CV   I GK   +  G 
Sbjct: 404 RECVEVIKQGLGMPAFNNDEIIIPSFIRRGVKKEDAYNYSAIGCVETAIPGKWGYRCTGM 463

Query: 435 ARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITA 494
           +  N  + +L  +NGG+D +   ++ P       D+ ++D++M   D  +  + +Q +  
Sbjct: 464 SFINFPRVLLLIMNGGIDPESGKRLLPDYGKFT-DMTSFDQLMTAWDKALREMTRQSVII 522

Query: 495 LNIIHYMHDKYSYEASLMALHDRDVIRTMACGI------------AGLSVAADSLSAIKY 542
            N      ++   +     L D  + R                   G++  ADSL+AIK 
Sbjct: 523 ENSCDLALEQNYPDILCSVLTDDCIGRGKTIKEGGAVYDFISGLQVGIANLADSLAAIKK 582

Query: 543 AKVK---------------PIRDEDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMK 587
              +                  DEDG  I   +  + P++GN+D  VDDL V+  + ++ 
Sbjct: 583 LVFEEKKLTTTQLWHALTTDFADEDGEKIRQMLINDAPKYGNDDDYVDDLIVEAYKPYID 642

Query: 588 KIQKLHTYR------DAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRD 641
           +I K    R        +      +I++NV  G  T  TPDGR A  P   G +P H  D
Sbjct: 643 EIAKYKNTRYGRGPIGGLRYAGTSSISANVGQGHSTLATPDGRHARTPLAEGCSPEHAMD 702

Query: 642 QKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIE 701
             G  A   SV+KL       G+     + P  L  D+   K  L  L+  +F+      
Sbjct: 703 TNGPTAVFKSVSKLSTKDITGGVLLNQKMSPQILRSDESCMK--LVALLRTFFNRLH--- 757

Query: 702 GGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQ 758
            G H+  N+++R+ L+DA  +P+K+  L +RV+GY+  F  L+KE Q D+I RT   
Sbjct: 758 -GYHVQYNIVSRDTLIDAQNHPDKHRDLIVRVAGYSAFFVGLSKETQDDIIERTEQS 813


>UniRef50_B2TJX0 Formate C-acetyltransferase n=9 Tax=Bacteria RepID=B2TJX0_CLOBB
          Length = 801

 Score =  686 bits (1770), Expect = 0.0,   Method: Composition-based stats.
 Identities = 167/780 (21%), Positives = 301/780 (38%), Gaps = 91/780 (11%)

Query: 57  KVMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGI 116
              +  K                     + + YI K  E IVG Q+       + P   +
Sbjct: 32  YFTKAYKENEDKP-IYIKRAKAVEKTLENMSIYI-KDGELIVGNQSFDERTAPIFPEYAV 89

Query: 117 KMIEGSCKAY----NRELDPMIK---------KIFTEYR-KTHNQGVFDVYTPDILRCRK 162
           + IE   K Y     RE D             +I   ++ KT     + +   +I +   
Sbjct: 90  QWIEDELKEYGNFNKREGDNFYINEKNIDELLEIVQYWKGKTLKDKCYGIMPEEIKKAIN 149

Query: 163 SGVLTGLPDA-YGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQAD----LENGVNLE-- 215
             V+ G  +   G G I+ D+ +    G+  ++K+       +        +    LE  
Sbjct: 150 VKVIHGEGNMTSGDGHIVPDFEKALNLGLSGIIKEAEEALEKVDISENDGFKKKSFLESV 209

Query: 216 ------------QTIRLREEIAEQHR---ALGQMKEMAAKYGYDISGPATNAQEAIQWTY 260
                       +   L +++A   +      ++  ++            N  EA+Q  +
Sbjct: 210 IIINKAIINFGLRYSELAKKLALAEKDINRKNELLLISDICLRIPKEAPKNFYEAVQMIW 269

Query: 261 FGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLR 320
           F +L      NG + S GR   +L  Y +  ++ G +TE  A+E++  L +KL  +  +R
Sbjct: 270 FVHLVIQIESNGHSASLGRVDQYLYPYYKEGIENGTLTEDFAKELLQCLWIKLFSILKIR 329

Query: 321 TPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKL 380
              +    +G P +   +IGG    G       S+  L ++  M    +PN++       
Sbjct: 330 PTSHAGYGAGYPTYQNVTIGGCNELGEDCTNSLSYLILQSVGEM-KLTQPNLSARLFSNS 388

Query: 381 PLNFKKFAA-KVSIDTSSLQYENDDLMRPDF--------NNDDYAIACCVSPMIVGK-QM 430
              F +  A  +           D+++            +  +Y +  CV   + GK   
Sbjct: 389 SARFIRECANVIKTGFGMPALHTDEIIVQSLLNKGVNYKDAYNYTMVGCVEVAVPGKWGY 448

Query: 431 QFFG-ARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAK 489
           +  G +  N+ K +   +N G DE+    +   +  +     N++E+    +  + +  K
Sbjct: 449 RCTGMSFLNMIKAVELTLNDGYDERTGETLLTGNRDLLS-FNNFEELWAAWEKNIAYYTK 507

Query: 490 QYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGI------------AGLSVAADSL 537
             + AL+ I   + +   +    +L D  + R  +                GL+ A +SL
Sbjct: 508 LTV-ALDKIADTNLEEFPDIFCSSLVDDCIGRGKSIKEGGSIYDIVAGLQVGLANATNSL 566

Query: 538 SAIKYAKVK---PIRDEDGLAIDFEIEG-----------EYPQFGNNDPRVDDLAVDLVE 583
            A+K          ++E   A+    EG             P++GN+   VD++A ++ +
Sbjct: 567 FALKDVIFDKNILSKEEVVNALKNNFEGLEGIKVKKILFSSPKYGNDIDCVDNMARNVYQ 626

Query: 584 RFMKKIQKLHTYR------DAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPM 637
            ++ +I K  T R        I   S   I+SNV  G  TG TPDGR A  P   GA+P+
Sbjct: 627 TYINEISKYKTTRYGRGPIGGIYGLSTSGISSNVPMGCVTGATPDGRFAWTPAAEGASPV 686

Query: 638 HGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHE 697
            G D +G  + L S+ KLP      G        PN L  DD+  K     L+  +   +
Sbjct: 687 QGSDIEGPTSVLKSITKLPTILMTGGQLLNMKFSPNLLVGDDQFTK--FINLIKSFVSMK 744

Query: 698 ASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFT 757
                G H+  NV++ + L +A ++PEKY  + +RV+GY  +F +L +  Q+D+I+RT  
Sbjct: 745 -----GWHIQFNVIDTKTLREAQKDPEKYRDVIVRVAGYCAQFVTLDQTTQEDIISRTEE 799


>UniRef50_P75793 Putative formate acetyltransferase 3 n=109 Tax=Bacteria
           RepID=PFLF_ECOLI
          Length = 810

 Score =  682 bits (1761), Expect = 0.0,   Method: Composition-based stats.
 Identities = 172/792 (21%), Positives = 322/792 (40%), Gaps = 95/792 (11%)

Query: 48  TEATTTLWDKVMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLK 107
           TE          E  +       PV    A+A  + +       K  E I+G Q      
Sbjct: 30  TERAQHY----TEMYQQHLDKPIPVRRALALAHHLAN--RTIWIKHDELIIGNQASEVRA 83

Query: 108 RALIPFGGIKMIE-GSCKAYNR---------ELDPMIKKIFTEYR-KTHNQGVFDVYTPD 156
             + P   +  IE       +R         E   ++ ++   +R +T     + ++T +
Sbjct: 84  APIFPEYTVSWIEKEIDDLADRPGAGFAVSEENKRVLHEVCPWWRGQTVQDRCYGMFTDE 143

Query: 157 ILRCRKSGVLTGLPDA-YGRGRIIGDYRRVALYGIDYLMKDKLAQ--------------- 200
                 +G++    +   G   +  ++  +   G+D L ++   +               
Sbjct: 144 QKGLLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLREEVAERRSRINLTVLEDLHGE 203

Query: 201 --FTSLQADL-ENGVNLEQTIRLREEIA---EQHRALGQMKEMAAKYGYDISGPATNAQE 254
               ++   L     ++E+   L  E+A    +     ++  MA         P     +
Sbjct: 204 QFLKAIDIVLVAVSEHIERFAALAREMAATETRESRRDELLAMAENCDLIAHQPPQTFWQ 263

Query: 255 AIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLK-AGKITEQEAQEMVDHLVMKL 313
           A+Q  YF  L      NG ++SFGR   +L  Y  RD++    +  + A EM+    +KL
Sbjct: 264 ALQLCYFIQLILQIESNGHSVSFGRMDQYLYPYYRRDVELNQTLDREHAIEMLHSCWLKL 323

Query: 314 RMVRFLRTPEYDELFSGDPIWATESIGGMG-LDGR--TLVTKNSFRFLNTLYTMGPSPEP 370
             V  +R+  + +  +G P++   +IGG   +DG+    V   S+  L +   +  S +P
Sbjct: 324 LEVNKIRSGSHSKASAGSPLYQNVTIGGQNLVDGQPMDAVNPLSYAILESCGRL-RSTQP 382

Query: 371 NMTILWSEKLPLNFKKFAAKVSI-DTSSLQYENDDLMRPDF--------NNDDYAIACCV 421
           N+++ +   +  +F     +V         + ND+++ P+F        +  DYA   C+
Sbjct: 383 NLSVRYHAGMSNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLGIEPQDAYDYAAIGCI 442

Query: 422 SPMIVGK-QMQFFG-ARANLAKTMLYAINGGVDEKLKMQVGPKSEPI-KGDVLNYDEVME 478
              + GK   +  G +  N A+ ML A+ GG D        P+ + +  G+  N+DEVM+
Sbjct: 443 ETAVGGKWGYRCTGMSFINFARVMLAALEGGHDATSGKVFLPQEKALSAGNFNNFDEVMD 502

Query: 479 RMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGI----------- 527
             D  + +  ++ I    ++  M ++  ++    AL D  + R  +              
Sbjct: 503 AWDTQIRYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAKSIKQGGAKYDWVSGL 562

Query: 528 -AGLSVAADSLSAIKYAKVKPIR---DEDG------------LAIDFEIEGEYPQFGNND 571
             G++   +SL+A+K    +       +                +   +    P++GN+D
Sbjct: 563 QVGIANLGNSLAAVKKLVFEQGAIGQQQLAAALADDFDGLTHEQLRQRLINGAPKYGNDD 622

Query: 572 PRVDDLAVDLVERFMKKIQKLHTYR------DAIPTQSVLTITSNVVYGKKTGNTPDGRR 625
             VD L     + ++ ++++ H  R               +I++NV +G +T  TPDGR+
Sbjct: 623 DTVDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISANVPFGAQTMATPDGRK 682

Query: 626 AGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTN 685
           A  P   GA+P  G D  G  A + SV KLP A    G+     + P  L  + +  K  
Sbjct: 683 AHTPLAEGASPASGTDHLGPTAVIGSVGKLPTAAILGGVLLNQKLNPATLENESD--KQK 740

Query: 686 LAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTK 745
           L  L+  +F     +  G H+  N+++RE LLDA ++P++Y  L +RV+GY+  F +L+ 
Sbjct: 741 LMILLRTFFE----VHKGWHIQYNIVSRETLLDAKKHPDQYRDLVVRVAGYSAFFTALSP 796

Query: 746 EQQQDVITRTFT 757
           + Q D+I RT  
Sbjct: 797 DAQDDIIARTEH 808


>UniRef50_D1AFQ7 Pyruvate formate-lyase n=3 Tax=Fusobacteriaceae RepID=D1AFQ7_SEBTE
          Length = 802

 Score =  679 bits (1751), Expect = 0.0,   Method: Composition-based stats.
 Identities = 162/793 (20%), Positives = 302/793 (38%), Gaps = 95/793 (11%)

Query: 45  AGATEATTTLWDKVMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEA 104
            G           + +  K        +    AV   +  + + YI K  E IVG Q+  
Sbjct: 23  PGVCVERA---RYLTKAYKENEEKSKYIKRALAVKE-VLENMSIYI-KDGELIVGNQSSD 77

Query: 105 PLKRALIPFGGIKMIEGSCK----AYNRELDPM---------IKKIFTEYR-KTHNQGVF 150
                L P   ++ I           +R+ D           + +I   ++ KT  +  +
Sbjct: 78  VRTAPLFPEYAVEWIIEELNEKGNFDHRDGDKFHLPEEHKKEVLEICEYWQGKTLREKCY 137

Query: 151 DVYTPDILRCRKSGVLTGLPDA-YGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQAD-- 207
                ++ +  +   + G  +   G G I+ D+ +    G+  ++ + +     +     
Sbjct: 138 AQMPEELQKASQVKAVHGEGNMTSGDGHIVPDFEKALKVGLRGIINEAVEARDKVDITVF 197

Query: 208 ---------LENGVNLEQTIRLR----------EEIAEQHRALGQMKEMAAKYGYDISGP 248
                        +  E  I              E     +   ++  +A          
Sbjct: 198 GGYDKRDFLDSIVILNEAVIDFAHRFSSLASEFAEKETDEKRKKELLTIAENCKNVPENS 257

Query: 249 ATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERD-LKAGKITEQEAQEMVD 307
                EA+Q  +F +L      NG + S GRT  +L  + ++D +    +  + A+E++ 
Sbjct: 258 PKTFWEAVQLIWFIHLVIQIESNGHSASLGRTDQYLYEFYKKDVITDKTMDREFAKELLQ 317

Query: 308 HLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPS 367
            L +KL  V  +R   +    +G P +   +IGG   DG     + ++  L ++      
Sbjct: 318 CLWVKLYTVIKVRPTSHSGYGAGYPTYQNVTIGGSNYDGSDACNELTYLILESVAE-NKM 376

Query: 368 PEPNMTILWSEKLPLNFKKFAAKVSI-DTSSLQYENDDLMRPDF--------NNDDYAIA 418
            +PN+ + +    P  F + +A V+           D+++ P          +  +Y + 
Sbjct: 377 TQPNLAVRFHSNSPEKFIRESASVAATGYGMPAMHTDEIIIPALLNKGVEFKDAYNYTMV 436

Query: 419 CCVSPMIVGK-QMQFFG-ARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEV 476
            CV   + GK   +  G    N  K +   IN G D +  M +   +  +  D  ++D++
Sbjct: 437 GCVEVAVPGKWGYRCTGMTFLNFIKIVELVINDGHDPRTGMTLYQGNGTLL-DFESFDDL 495

Query: 477 MERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGI--------- 527
            +  +  + +  +  + AL+++   H +   +    +L D  + R               
Sbjct: 496 WKSWEKNIAYYTRLSV-ALDVLADTHLEELPDILCSSLIDSCIERGKTAKEGGAKYDIIA 554

Query: 528 ---AGLSVAADSLSAIKYAKVKP---IRDEDGLAIDFEIEG-----------EYPQFGNN 570
               GLS AA+++ A+K    +     ++E   A+    EG             P++GN+
Sbjct: 555 GLQVGLSNAANAMYALKKTVFEDKVLTKEEVFEALKNNFEGIDGERVRNILLNVPKYGND 614

Query: 571 DPRVDDLAVDLVERFMKKIQKLHTYRDAI------PTQSVLTITSNVVYGKKTGNTPDGR 624
              +D   V   E ++++I K    R            S   I+SNV  G  TG TPDGR
Sbjct: 615 IDEIDRFTVKTYEPYIEEIAKYKNTRYGRGPINGGYGLSTSGISSNVPMGTVTGATPDGR 674

Query: 625 RAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKT 684
            A  P   GA+P  G D KG  A L S+ KLP      G        P+ +  +D+  K 
Sbjct: 675 YAYTPAAEGASPTQGTDVKGPTAVLNSIVKLPTLLITGGQLLNQKYSPDLIKSEDQFEK- 733

Query: 685 NLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLT 744
              G++  + + +     G H+  N+++R+ L  A E+PEKY  + +RV+GY  +F +L 
Sbjct: 734 -FVGIIKTFINLK-----GWHIQFNIISRDTLQAAKEDPEKYRDIVVRVAGYCAQFVTLD 787

Query: 745 KEQQQDVITRTFT 757
              Q+D+I RT  
Sbjct: 788 PITQEDIIARTEQ 800


>UniRef50_A6LQ73 Pyruvate formate-lyase n=6 Tax=Bacteria RepID=A6LQ73_CLOB8
          Length = 784

 Score =  672 bits (1733), Expect = 0.0,   Method: Composition-based stats.
 Identities = 171/765 (22%), Positives = 297/765 (38%), Gaps = 80/765 (10%)

Query: 58  VMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIK 117
           + E  K        +    A+ ++++  + G      E IVG +T+      + P  G  
Sbjct: 32  ITETYKENEDKPVIIKRALALKNSLSKLEIG--VDDEELIVGNRTKGVRYGVVFPESGSS 89

Query: 118 MI-EGSCKAYNRELDPMI----------KKIFTEYRK-THNQGVFDVYTPDILRCRKSGV 165
            I +       R  D             K I   +   +    +   Y  +I     + V
Sbjct: 90  WIDKEFESLPTRPQDKFNVNLNDIETFRKVIKPYWDGHSLEDVIRQRYGKEIDEI--AKV 147

Query: 166 LTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLENGVNLEQTI------- 218
           +      + +G I  + R     G + + +  + +     +  E+    E  I       
Sbjct: 148 VKINQKDHAQGHICPNCREWLALGPEGIKQRAIEKMK--NSTKESKEFYESVIIVMEGAQ 205

Query: 219 -------RLREEIAE---QHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVK 268
                   L +E AE   +   +  M ++A         PA    EA+Q  +F ++    
Sbjct: 206 EFMMRYHDLMKEKAESICEEELVADMLQVAEICKNISRRPAQTFHEAVQAIWFLFVILHM 265

Query: 269 SQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELF 328
             N ++ S GR   FL  Y +RD+  G I +++A E+++ L +K   + +LR     + F
Sbjct: 266 ESNASSFSPGRMDEFLYPYYKRDIHLGNIDDKKALEIIECLWLKFNEIVYLRNSHSAKFF 325

Query: 329 SGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFA 388
           +G PI    +IGG          + SF FL     +G  P+PN+++   +       K +
Sbjct: 326 AGFPIGFNIAIGGQDEKSNDFSNELSFLFLKAQEHLG-LPQPNLSVRLHKNTSEKLLKES 384

Query: 389 AK-VSIDTSSLQYENDDLMRPDF--------NNDDYAIACCVSPMIVGKQMQFFG-ARAN 438
            K V+  +   Q+ ND+ + P          +  DYAI  CV     G  + +   A  N
Sbjct: 385 IKVVAKGSGMPQFFNDESVVPSMIDLGIKEKDARDYAIVGCVELTTQGNNLGWSDAAMFN 444

Query: 439 LAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNII 498
           L K +   +NGG        +      +      Y+++ E     +D+   + I A   +
Sbjct: 445 LNKVLEITLNGGKCLISGDSLSQDLGNLTT-YEKYEDLEEAFAKQIDYFIDRMILACEQV 503

Query: 499 HYMHDKYSYEASLMALHDRDVIRTMACGIAG------------LSVAADSLSAIK---YA 543
              H        L ++ D  + + +     G            ++  ADSL+AIK   Y 
Sbjct: 504 EKAHIDVLPSPFLSSVIDDCIEKGVDVTAGGAVYNLSGIQMIQVANLADSLAAIKLLVYD 563

Query: 544 KVKPIRDEDGLAIDFEIEG----------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLH 593
           + +  ++E   A+    EG            P++GN+   VD++       F  K++   
Sbjct: 564 EKRISKEELLKALQNNFEGYEVIRAMLLNRAPKYGNDIQWVDEIGAKWARYFNGKLKSYT 623

Query: 594 TYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGP-GANPMHGRDQKGAVASLTSV 652
            YR       + T++++V  G+  G + DGR A AP    G +P++GRD  G  A L SV
Sbjct: 624 NYRGGKYHTGMYTVSAHVPMGENVGASADGRYAKAPLADGGMSPVYGRDIAGPTAVLKSV 683

Query: 653 AKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMN 712
           +KL      +G       +P       E+ +   A  +  +   E       H+  NV+ 
Sbjct: 684 SKLDNVLTTNGGLLNMKFLPEFFK--HEIGRDKFARFLRTFVDLE-----IPHIQFNVLR 736

Query: 713 REMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFT 757
           +E LL A ++PE Y  LT+RV+GY   F  L  E Q ++I RT  
Sbjct: 737 KEDLLAAQKDPENYRSLTVRVAGYTAYFTELAGELQNEIIARTSY 781


>UniRef50_B1C5P6 Putative uncharacterized protein n=3 Tax=Bacteria
           RepID=B1C5P6_9FIRM
          Length = 824

 Score =  668 bits (1724), Expect = 0.0,   Method: Composition-based stats.
 Identities = 171/778 (21%), Positives = 307/778 (39%), Gaps = 88/778 (11%)

Query: 58  VMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIK 117
           + E  +        V    ++   I  + + Y+    + ++G Q     +  L P     
Sbjct: 57  ITESYERYKDEPIIVKRALSL-RDILLNMSIYLE-DEQLVIGNQASGIRRAPLFPEYSWD 114

Query: 118 MI-EGSCKAYNRELDPMI---------KKIFTEYR-KTHNQGVFDVYTPDILRCRKSGVL 166
            I +   +   R  D            ++I   ++ KT    V    T ++L  +K GVL
Sbjct: 115 WIFKEIDEFEKRPSDVFYVNEENKKIMREILPLWKGKTLKDRVLKTQTKEVLEDKKVGVL 174

Query: 167 TGLPDA-YGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQADL----------------- 208
               +   G G II ++ +V   G   ++ +   + + L                     
Sbjct: 175 GWEGNVTAGEGHIIMNFEKVLKVGFRGIVNEAEDKLSKLDYTDPDDLRKVSFYKAVKIVY 234

Query: 209 -ENGVNLEQTIRLRE---EIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYL 264
             +   +E+ I L E    I +  +   ++K++          P T  + A+Q  +F  L
Sbjct: 235 SASSEFVERYIDLLEGKIIIEKDEQRKKELKQIKKNCENIEYNPPTTFKSAVQLLWFVQL 294

Query: 265 AAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEY 324
            +    NG +MS GR   ++  + +RD+  G +   EA+E ++   +KL  V  +R   +
Sbjct: 295 ISQIEANGHSMSMGRVDKYIYPFYKRDIDKGILNRDEAKEYIECFYLKLFTVIKIRPWSH 354

Query: 325 DELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNF 384
               +G P +    IGG  +DG++ + + S+  L  L  +    EPN  I   E +P +F
Sbjct: 355 TRFVAGYPTYQNIIIGGKNIDGKSDLNEMSYILLEALGDI-KLSEPNFYIRCHEDMPKDF 413

Query: 385 KKFAAK-VSIDTSSLQYENDDLMRPDF--------NNDDYAIACCVSPMIVGKQMQFFGA 435
                K + +        NDD++            +  DY+   C+   + GK       
Sbjct: 414 VDLMIKVIKMGFGMPALVNDDVIINSLIDRGVSKEDAYDYSTMGCLEVQVPGKWGYRANG 473

Query: 436 --RANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYIT 493
             + N+ K M  A+NGGVD K  ++   +  P      ++DEV +     M +  +  +T
Sbjct: 474 KTKVNVLKIMEIALNGGVDPKSGIKT-IEGIPEFTKFTDFDEVYKAYCKAMIYYMRLQVT 532

Query: 494 ALNIIHYMHDKYSYEASLMALHDRDVIRTMACG------------IAGLSVAADSLSAIK 541
           A NI     ++   +A    L +  + R                 + G     +SL A+K
Sbjct: 533 ADNINDIAMEELVPDAFCSGLVEDCIGRGKTIKEGGAVYDMISGALVGGPNVGNSLYALK 592

Query: 542 YAKVKPIRDED---------------GLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFM 586
            A  +                     G  I   ++ +  ++GN++   DD+ V + + ++
Sbjct: 593 KAVFEDKLLTLEDVQNAVRSNYEGIEGEKIRLLLQNKIDKYGNDNDEADDMVVKIYKPYI 652

Query: 587 KKIQKLHTYR------DAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGR 640
             I      R        +   S +TI+SNV  G K G TPDGR+   P   G +PMHG 
Sbjct: 653 DNIASYKNTRFGRGPIGGMFIPSTVTISSNVPDGAKVGATPDGRKDEEPTAEGVSPMHGT 712

Query: 641 DQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASI 700
           ++ G  + + SV+KL       G        P  +    +  K     L++ +F      
Sbjct: 713 EKNGPTSVINSVSKLETRKMTGGQLLNMRFNPTTVKTKKDEEK--FYALIEAFFK----- 765

Query: 701 EGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQ 758
           + G H+  N+++ + L+ A + PEKY  L +RV+GY+  F SL K  Q D+I+R   +
Sbjct: 766 KNGWHVQFNMISTDTLIKAQKEPEKYQDLVVRVAGYSALFTSLDKITQDDIISRMEYE 823


>UniRef50_A8GF53 Pyruvate formate-lyase n=31 Tax=Bacteria RepID=A8GF53_SERP5
          Length = 810

 Score =  668 bits (1724), Expect = 0.0,   Method: Composition-based stats.
 Identities = 160/792 (20%), Positives = 317/792 (40%), Gaps = 95/792 (11%)

Query: 48  TEATTTLWDKVMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLK 107
           TE          E  +       PV    A+A+ +            E I+G Q      
Sbjct: 30  TERAQH----YTEAYQQHLDKPLPVRRALALANHLAK--RTLRIDNDELIIGNQASELRA 83

Query: 108 RALIPFGGIKMIE-GSCKAYNR---------ELDPMIKKIFTEYR-KTHNQGVFDVYTPD 156
             + P   +  IE    +  +R         E   ++ +I   +R +T     + ++T +
Sbjct: 84  APIFPEYTVSWIEDEIDQLADRPGAGFSISEENKAILHRICPWWRGQTVQDRCYGMFTDE 143

Query: 157 ILRCRKSGVLTGLPDA-YGRGRIIGDYRRVALYGIDYLMKDKLAQ--------------- 200
                 +G++    +   G   +  ++  +   G+D L      +               
Sbjct: 144 QRALLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLRDKVDERRSRIHLTDWQELQQE 203

Query: 201 --FTSLQADLENG-VNLEQTIRLREEIAE---QHRALGQMKEMAAKYGYDISGPATNAQE 254
               ++   LE    ++ +   L   +A+   +H    +++ +A         P     +
Sbjct: 204 QFLKAIDLTLEALSAHILRFAELARSMAQAESRHWRSEELQAIAENCELIAHRPPQTFWQ 263

Query: 255 AIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLK-AGKITEQEAQEMVDHLVMKL 313
           A+Q  YF  L      NG ++SFGR   +L  +  RD++    +  + A EM+    +KL
Sbjct: 264 ALQLCYFIQLTLQIESNGHSVSFGRLDQYLYPWYRRDVELEQTLPRERAIEMLHSCWLKL 323

Query: 314 RMVRFLRTPEYDELFSGDPIWATESIGGMG-LDG--RTLVTKNSFRFLNTLYTMGPSPEP 370
             +  +R+  + +  +G P++   +IGG   +DG  R  V   S+  L +   +  S +P
Sbjct: 324 LEINKIRSGSHSKASAGSPLYQNVTIGGQQLVDGSPRDAVNPLSYTILESCGRL-RSTQP 382

Query: 371 NMTILWSEKLPLNFKKFAAKVSI-DTSSLQYENDDLMRPDF--------NNDDYAIACCV 421
           N+++ +   +  +F     +V         + ND+++ P+F        +  DYA   C+
Sbjct: 383 NLSVRYHAGMSSDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLGVEPQDAYDYAAIGCI 442

Query: 422 SPMIVGK-QMQFFG-ARANLAKTMLYAINGGVDEKLKMQVGPKSEPI-KGDVLNYDEVME 478
              + GK   +  G +  N A+ +L A+  G D        P+   + +G+  ++D+V+ 
Sbjct: 443 ETAVGGKWGYRCTGMSFINFARVLLAALEQGRDATSGKVFLPQELALSRGNFSHFDQVLG 502

Query: 479 RMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGI----------- 527
             D  + +  ++ I    ++  + ++ +++    AL D  + R  +              
Sbjct: 503 AWDSQIRYYTRKSIEIECVVDSVLEENAHDILCSALVDDCIERGKSIKQGGAKYDWVSGL 562

Query: 528 -AGLSVAADSLSAIKYAKVK---------------PIRDEDGLAIDFEIEGEYPQFGNND 571
             G++   +SL+A++    +                     G  +   +    P++GN+ 
Sbjct: 563 QVGIANLGNSLAAVRKLVFEQGAIGQQQLAAALANDFDGLSGEQLRQRLLNAAPKYGNDV 622

Query: 572 PRVDDLAVDLVERFMKKIQKLHTYR------DAIPTQSVLTITSNVVYGKKTGNTPDGRR 625
             VD L V   + ++ ++ + H  R               +I++NV +G  T  TPDGR+
Sbjct: 623 DEVDQLLVRAYQSYIDELAQYHNTRFGRGPIGGTYYAGTSSISANVPFGAATLATPDGRK 682

Query: 626 AGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTN 685
           A  P   GA+P  G D  G  A   S++KLP A    G+     + P  L    +  +  
Sbjct: 683 AHTPLAEGASPASGTDHLGPTAVFNSLSKLPTAAILGGVLLNQKLNPATLENPVD--REK 740

Query: 686 LAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTK 745
           L  ++  +F        G H+  N+++RE LL+A ++P++Y  L +RV+GY+  F +L+ 
Sbjct: 741 LMLMLRTFFETYL----GWHVQYNIVSRETLLEAKQHPDQYRDLVVRVAGYSAFFTALSP 796

Query: 746 EQQQDVITRTFT 757
           + Q D+I RT  
Sbjct: 797 DAQDDIIARTEH 808


>UniRef50_B2ISH7 Formate acetyltransferase, putative n=59 Tax=Bacteria
           RepID=B2ISH7_STRPS
          Length = 815

 Score =  666 bits (1719), Expect = 0.0,   Method: Composition-based stats.
 Identities = 170/752 (22%), Positives = 304/752 (40%), Gaps = 85/752 (11%)

Query: 82  ITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIK-MIEGSCKAYNRELDPMI------ 134
           I  + + YI ++   I G Q  +     + P   ++ ++        R+ D         
Sbjct: 71  ILENMSIYIEEES-MIAGNQASSNKDAPIFPEYTLEFVLNELDLFEKRDGDVFYITEETK 129

Query: 135 ---KKIFTEYRKT-HNQGVFDVYTPDILRCRKSGVLTGLPDA-YGRGRIIGDYRRVALYG 189
              + I   +           +   ++    ++G          G   +  +Y+++  +G
Sbjct: 130 EQLRSIAPFWENNNLRARAGALLPEEVSVYMETGFFGMEGKMNSGDAHLAVNYQKLLQFG 189

Query: 190 IDYLMKDKLAQFTSLQADLENGV------------------NLEQTIRLREEIAEQ--HR 229
           +    +       +L       +                    ++ + L + +AE    +
Sbjct: 190 LRGFEERARKAKVALDLTDPASIDKYHFYDSIFIVIDAIKVYAKRFVALAKSLAENANPK 249

Query: 230 ALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIE 289
              ++ E+A         PAT   EAIQ  +F         NG ++S+GR   ++  Y++
Sbjct: 250 RKKELLEIADICSRVPYEPATTFAEAIQSVWFIQCILQIESNGHSLSYGRFDQYMYPYMK 309

Query: 290 RDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTL 349
            DL++GK TE    E + +L +K   +  +R+  +    +G P++   +IGG   D +  
Sbjct: 310 ADLESGKETEDSIVERLTNLWIKTITINKVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDA 369

Query: 350 VTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKV-SIDTSSLQYENDDLMRP 408
           V   S+  L ++      P+PN+T+ +   L   F     +V  +      + ND+++ P
Sbjct: 370 VNPLSYLVLKSVAQ-THLPQPNLTVRYHAGLDARFMNECIEVMKLGFGMPAFNNDEIIIP 428

Query: 409 DF--------NNDDYAIACCVSPMIVGK-QMQFFG-ARANLAKTMLYAINGGVDEKLKMQ 458
            F        +  DY+   CV   + GK   +  G +  N  K +L  +N G+D     +
Sbjct: 429 SFIAKGVLEDDAYDYSAIGCVETAVPGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKR 488

Query: 459 VGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRD 518
             P     K D+ N+ E+    D  + +L +  +   N I    ++   +    AL D  
Sbjct: 489 FAPSFGHFK-DMKNFSELENAWDKTLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDC 547

Query: 519 VIRTMACGI------------AGLSVAADSLSAIKYAKVKPIR---------------DE 551
           + R                   G++  +DSL+AIK    +  R                E
Sbjct: 548 IGRGKHLKEGGAVYDYISGLQVGIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGE 607

Query: 552 DGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYR------DAIPTQSVL 605
           +G  I   +  + P++GN+D   D L     + ++ +I K    R        I      
Sbjct: 608 EGKVIQEMLIHDAPKYGNDDDYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTS 667

Query: 606 TITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGIS 665
           +I++NV  G+ T  TPDGR AG P   G +P H  DQ G  + L SV+KLP      G+ 
Sbjct: 668 SISANVGQGRGTLATPDGRNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVL 727

Query: 666 YTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEK 725
               + P  L K+++  K  L  L+  +F+       G H+  NV++RE L+DA ++PEK
Sbjct: 728 LNQKVNPQTLAKEED--KLKLIALLRTFFNRLH----GYHIQYNVVSRETLIDAQKHPEK 781

Query: 726 YPQLTIRVSGYAVRFNSLTKEQQQDVITRTFT 757
           +  L +RV+GY+  FN L+K  Q D+I RT  
Sbjct: 782 HRDLIVRVAGYSAFFNVLSKATQDDIIGRTEH 813


>UniRef50_B8G188 Pyruvate formate-lyase n=1 Tax=Desulfitobacterium hafniense DCB-2
           RepID=B8G188_DESHD
          Length = 796

 Score =  663 bits (1712), Expect = 0.0,   Method: Composition-based stats.
 Identities = 155/770 (20%), Positives = 291/770 (37%), Gaps = 85/770 (11%)

Query: 58  VMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIK 117
           V E  +    +        A+   + + D        E IVG     P    + P   +K
Sbjct: 43  VTESYEETFGSSYIYRRAKALEKVLLNMDI--CINDKELIVGSYAGKPRGCQVFPEYDMK 100

Query: 118 -MIEGSCKAYNRELDPM---------IKKIFTEYRK-THNQGVFDVYTPDILRCRKSGVL 166
            +++   +   R+ D            ++I+ +++  T      +++  +  +  +  + 
Sbjct: 101 FLVDEMDEFALRQADKFTISEDNKAIARQIYEKWKGNTITDQALNLFPEEAAKASQQLIF 160

Query: 167 TGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLEN-----------GVNLE 215
                  G G ++ +Y +V   G+   M +       L                  +  +
Sbjct: 161 LLTCLGSGIGHMLVNYEKVIQKGLAGFMLEIEELENGLDICDPEYNDKKTYYQSLTIVCQ 220

Query: 216 QTIRLR----------EEIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLA 265
              +             E     +   ++ ++A       + PA N  +A+Q  +F  L 
Sbjct: 221 AVCKFAGRFSLLALAQAEKTADPQRKEELLQIAENCRRVPAQPAQNFWQALQALWFVQLV 280

Query: 266 AVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYD 325
                NG ++S GR   ++  Y      A +  +   +E++  L +K   +  +R     
Sbjct: 281 LHLESNGHSVSPGRFDQYMYPYY-----AAETDKDACEELLHCLWLKFFELNKIRNKVSS 335

Query: 326 ELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFK 385
            +F G P++    +GG   +G + V + S   L     +   P+P++++ W    P  F 
Sbjct: 336 VVFGGYPMFQNIVVGGQNANGESAVNELSHLCLEATAKV-HLPQPSLSVRWFYGCPEEFI 394

Query: 386 KFAAK-VSIDTSSLQYENDDLMRPDF--------NNDDYAIACCVSPMIVGKQM-QFFGA 435
           + A + VS  T      ND+++ P+            DYAI  C    +  K      G 
Sbjct: 395 RHALEVVSYGTGMPALFNDEVIIPNMLQLGYTIEEARDYAIIGCTEMNVPHKTEPFLTGG 454

Query: 436 RANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITAL 495
             N+ K +   I  G D   + Q   +S  ++     ++E  +     + +  +Q++T  
Sbjct: 455 FLNILKILELTIFDGFDPVSQTQQAFQSGCVES-FTTFEEFQKAYYEQLSYYLRQHVTCD 513

Query: 496 NIIHYMHDKYSYEASLMALHDRDVIRTM------------ACGIAGLSVAADSLSAIKYA 543
           NI+  +H K         L    +                   + G++  ADSL+ IK  
Sbjct: 514 NILDALHGKICPTPFESMLLSDCLENGKSNLEGGARYNTTTLQLVGMANVADSLATIKKL 573

Query: 544 KVKPIRD-------------EDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQ 590
                               ED   +   I    P++GN+   VD L  D+V    ++  
Sbjct: 574 IYVEKSLTWNQLKAALQNNYEDDELLRQRIINHVPKYGNDHDFVDRLGRDVVYHCCREAA 633

Query: 591 KLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGP-GANPMHGRDQKGAVASL 649
           K  + R+     +V T+ +NV++  K G TPDGR+ G+     G +  HG D+ G  A  
Sbjct: 634 KYRSPRNGTYNIAVYTLATNVLWASKVGATPDGRKMGSVLADGGVSCSHGMDKNGLTALF 693

Query: 650 TSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVN 709
            SV K+              + P++  + D  +      ++  +F ++     GQH+  N
Sbjct: 694 NSVRKIDPYKPLGSALLNIRLSPSSFNETDFQKT---VDVVKSFFMNK-----GQHVQFN 745

Query: 710 VMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQS 759
           V +   L DA +NPEKYP L +RV+G++V F ++    Q+D+I RT   S
Sbjct: 746 VFDVNALRDAQKNPEKYPLLMVRVAGFSVLFTTIETILQEDIINRTLHSS 795


>UniRef50_Q18AX8 Glycerol dehydratase n=8 Tax=Clostridium RepID=Q18AX8_CLOD6
          Length = 790

 Score =  658 bits (1699), Expect = 0.0,   Method: Composition-based stats.
 Identities = 156/738 (21%), Positives = 298/738 (40%), Gaps = 79/738 (10%)

Query: 93  QLEKIVGLQTEAPLKRALIPFGGIKMI-EGSCKAYNRELDPMI----------KKIFTEY 141
           + E IVG   +      L P    + + +       R  DP +          K+IF  +
Sbjct: 62  ENELIVGTAGKFRRTGILTPEFSWQWVDKEMDTFDKRTQDPYVISKEQIEFIRKEIFPYW 121

Query: 142 RKTHNQGVFDVYTPD--ILRCRKSGVLTGLPDAY-GRGRIIGDYRRVAL-YGIDYLMKDK 197
           +    + VF    P+        +G++          G +  DY+ +    G   + +D 
Sbjct: 122 KGKSLEEVFLARIPEDTAKILVDTGIIDNDSKWRQAVGEVTPDYQDILFVKGYKGIKEDA 181

Query: 198 LAQFTSLQADLENGV------------------NLEQTIRLREEIAEQH---RALGQMKE 236
             +   L   +   +                    ++   L +E+++Q    +   ++ +
Sbjct: 182 DKKIKELDISVSENIEKIDFYKSVSIVAQGIMTLAQRYSNLAKEMSKQETDEKRKLELIK 241

Query: 237 MAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGK 296
           ++       + P TN  EAIQ+ +F  L  + S+N  A++ GR   ++  Y E D + GK
Sbjct: 242 ISEICMNVPANPPTNFYEAIQFVWFVQLGGILSENPLALNLGRFDQYMYPYYENDAREGK 301

Query: 297 ITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFR 356
           ITE EAQE+++ L +KL    +  +      F+G   +   ++GG   +G       S+ 
Sbjct: 302 ITESEAQELIEALWIKLSEWVWTISANTANYFAGYNQFQNLTVGGKKRNGTDGTNDISYM 361

Query: 357 FLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAK-VSIDTSSLQYENDDLMRPDF----- 410
            L    ++  + +P +++  S+  P NF    AK V   T      +D            
Sbjct: 362 CLKATESV-KTHQPGLSVRVSQGAPDNFVMAVAKLVKQGTGFPAIHSDSAGAQMLLQDGY 420

Query: 411 ---NNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIK 467
              +  D++   CV P              N A  + YA+N G       ++G  ++ I 
Sbjct: 421 DAEDARDWSNCGCVVPHFRKTGQWTSAVNINFAAALEYAMNEGKSRLTGEKMGLDTKNIT 480

Query: 468 GDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACG- 526
            +  +++E+ +     + +L K  +    +   +H +      L    D  + + +    
Sbjct: 481 -EFTSFEELKDEFLKQLAYLVKSSVIGTTVAQQIHKEMVPRPFLSTCVDGCLDKGVDLSK 539

Query: 527 ------------IAGLSVAADSLSAIKYAKVKP---IRDEDGLAIDFEIEG--------- 562
                         GL V ++SL+AIK    +      +E   A++ + EG         
Sbjct: 540 GGAKYNIGPVLTGIGLGVVSNSLAAIKKLVFEDKVTTLEELTKALNNDWEGYEELRKLAL 599

Query: 563 EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPD 622
           + P++GN++  VD LA+++ + +  + +K      +    + + I++ V  GK  G TP 
Sbjct: 600 DVPKYGNDNDYVDSLAIEVSDFYYTETRKYKDIFGSKFNSAFMGISNYVPTGKIVGATPC 659

Query: 623 GRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVR 682
           GR+A  P   G +P  G D    +A++ S +K+       G      +  + +  +  +R
Sbjct: 660 GRKATKPLTEGVSPFVGTDTTSPLAAMKSASKINHDVHTGGTLLNLRLNQDLVETERGLR 719

Query: 683 KTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNS 742
             NL  ++  YF       GG H+  N ++ + LL A ENPE+Y  L +RV+GY+ +F +
Sbjct: 720 --NLTSMIKSYFAL-----GGFHVQFNTISNDTLLKAQENPEEYKDLLVRVAGYSTQFVN 772

Query: 743 LTKEQQQDVITRTFTQSM 760
           L++E Q  +I R    + 
Sbjct: 773 LSREMQDAIIARNSHSNF 790


>UniRef50_Q1A666 Glycerol dehydratase n=8 Tax=Clostridiales RepID=Q1A666_9FIRM
          Length = 843

 Score =  655 bits (1691), Expect = 0.0,   Method: Composition-based stats.
 Identities = 180/823 (21%), Positives = 292/823 (35%), Gaps = 139/823 (16%)

Query: 56  DKVMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGG 115
           + + E  K        +         I  +    I +  E IVG  T AP      P   
Sbjct: 35  ELITESFKATEGQPVVM-RKARAFEHILKNLPI-IIRPEELIVGSTTIAPRGCQTYPEFS 92

Query: 116 IKMIE-GSCKAYNRELDPMI------KKIFT---EYRKTHNQGVFDVYT-PDILRCRKSG 164
            + +E        R  DP        K++      ++      +   Y  P+ LR  K  
Sbjct: 93  YEWLEAEFETVETRSADPFYISEETKKRLLAADAYWKGKTTSELATSYMAPETLRAMKHN 152

Query: 165 VLTGLPDAY-GRGRIIGDYRRVALYGIDYLMKDKLAQFTS------------------LQ 205
             T     Y G G +   Y  V   G++ + +    +  +                  L 
Sbjct: 153 FFTPGNYFYNGVGHVTVQYETVLAIGLNGVKEKVRKEMENCHFGDADYSTKMCFLESILI 212

Query: 206 ADLENGVNLEQTIRLREEIAE---QHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFG 262
           +         +  ++ EE+AE         ++  +A         PA + QEA Q  +F 
Sbjct: 213 SCDAVITYANRYAKMAEEMAEKETDAARRQELLTIARVCKNVPEFPAESFQEACQSFWFI 272

Query: 263 YLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTP 322
                   +G ++S GR   ++  Y E+DLK G +T + AQE++D + +KL  +   R  
Sbjct: 273 QQVLQIESSGHSISPGRFDQYMYPYYEKDLKEGSLTREYAQELIDCIWVKLNDLNKCRDA 332

Query: 323 EYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPL 382
              E F+G  ++    +GG  + GR      SF  +     +   P P+++I        
Sbjct: 333 ASAEGFAGYSLFQNLIVGGQTVQGRDATNDLSFMCITASEHVF-LPMPSLSIRVWHGSSK 391

Query: 383 NFKKFAAKVSI-DTSSLQYENDDLMRPDF--------NNDDYAIACCVSPMIVGKQMQFF 433
                AA+++        Y ND+++ P             +Y I  CV P + GK   + 
Sbjct: 392 ALLMRAAELTRTGIGLPAYYNDEVIIPALVHRGATMDEARNYNIIGCVEPQVPGKTDGWH 451

Query: 434 G-ARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYI 492
             A  N+ + +    + G D         ++  ++    ++DE ME     M +  +  +
Sbjct: 452 DAAFFNMCRPLEMVFSNGYDN--GEIASIQTGNVES-FQSFDEFMEAYRKQMLYNIELMV 508

Query: 493 TALNIIHYMHDKYSYEASLMALHDRDVIRTMAC------------GIAGLSVAADSLSAI 540
            A N I Y H K +       L D  + R M+                G++  ADSL  I
Sbjct: 509 NADNAIDYAHAKLAPLPFESCLVDDCIKRGMSAQEGGAIYNFTGPQGFGIANVADSLYTI 568

Query: 541 KYAKVKP---IRDEDGLAIDFEIEGEYPQFGNNDPRVDDLA------------------- 578
           K    +       E   A++          G +     D+A                   
Sbjct: 569 KKLVFEEKRITMGELKKALEMNYGK-----GLDATTAGDIAMQVAKGLKDAGQEVGPDVI 623

Query: 579 ----------------VDLVERFMKKIQKLHTY--------------------------- 595
                               E   + I +L  Y                           
Sbjct: 624 ANTIRQVLEMELPEDVRKRYEEIHEMILELPKYGNDIDEVDELAREAAYFYTRPLETFKN 683

Query: 596 -RDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAK 654
            R  +    +  +++NV  G +TG TPDGR A  P   G  P  G D  G  AS  SVAK
Sbjct: 684 PRGGMYQAGLYPVSANVPLGAQTGATPDGRLAHTPVADGVGPTSGFDISGPTASCNSVAK 743

Query: 655 LPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNRE 714
           L  A A +G  +   + P A+  +  +   +   L+ GYF  +     G H+  NV++R 
Sbjct: 744 LDHAIASNGTLFNMKMHPTAMAGEKGLE--SFISLIRGYFDQQ-----GMHMQFNVVDRA 796

Query: 715 MLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFT 757
            LLDA  +PEKY  L +RV+GY+  F +L+K  Q D+I RT  
Sbjct: 797 TLLDAQAHPEKYSGLIVRVAGYSALFTTLSKSLQDDIIKRTEQ 839


>UniRef50_C7X781 Pyruvate formate-lyase n=3 Tax=Bacteroidales RepID=C7X781_9PORP
          Length = 810

 Score =  655 bits (1689), Expect = 0.0,   Method: Composition-based stats.
 Identities = 166/768 (21%), Positives = 291/768 (37%), Gaps = 84/768 (10%)

Query: 65  ENRTHAPVDFDTAVAST---ITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIKMIEG 121
               +         A     I      YI  + E IVG +   P      P      +E 
Sbjct: 55  YQENYGKYPIPILRALNFLEICKRKTIYI-GEDELIVGERGPRPKAVPTFPELTCHSVED 113

Query: 122 SCKAYNREL----------DPMIKKIFTEYR-KTHNQGVFDVYTPDILRCRKSGVLTGLP 170
                 REL          D   +++   ++ +T  + +F     +     + G+ T   
Sbjct: 114 LHILNTRELQRYTISQEDIDTYEREVIPYWKGRTQRERIFSHVPKEWKEAYEVGMFTEFM 173

Query: 171 DAYGRGRIIGDYRRVALYGIDYLMK------------------DKLAQFTSLQADLENGV 212
           +    G    D  +V  YG+  L K                  DK  + T++    +  +
Sbjct: 174 EQRAPGHTALD-GKVYQYGLLDLKKRIEGELSALDFMNDPEATDKQEELTAMSISCDAAI 232

Query: 213 NL-EQTIRLREEI---AEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVK 268
            L E+   L +E+    +  R   +++++A    +  +       EAIQ  +F +L  + 
Sbjct: 233 LLAERHADLADEMSLTEKDPRRAAELRKIAEVCRWVPAHAPRTYWEAIQMYWFVHLGTIT 292

Query: 269 SQNG-AAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVR-FLRTPEYDE 326
             NG  AM+ G     L  + E+++ AG +T  EA+E++    +K+       +     +
Sbjct: 293 ELNGWDAMNPGHFDQHLAPFYEKEIAAGTLTRDEAKELMSCFFIKVNNHTAPPKVGITAK 352

Query: 327 LFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKK 386
                  +   +IGG+  DG   V++ S+  L T+  +    +P   I  S + P  F +
Sbjct: 353 ESGTYNDFTNLNIGGIRADGSDGVSEVSYIMLETIEELHIL-QPGSAIHVSARTPERFLR 411

Query: 387 FAAKVSI-DTSSLQYENDDLMRPDF--------NNDDYAIACCVSPMIVGKQMQFFGARA 437
              KV           N D+   +         +  +   + C+     GK+        
Sbjct: 412 AGCKVIRQGHGYPSVFNPDVYVQELMRQGKSLRDAREGGCSGCIEVGAFGKEAYVLTGYL 471

Query: 438 NLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNI 497
           N+ K +   ++ GVD     +VG ++   +G    Y+E+       + +     +   N 
Sbjct: 472 NVPKILEVTLHNGVDPVSGRKVGLETGDPRG-FRTYEELYAAFMRQIHYFVDMKVRVSNY 530

Query: 498 IHYMHDKYSYEASLMALHDRDVIRTMA------------CGIAGLSVAADSLSAIKYAKV 545
           I  M  KY+    L    D  + +                   GL    DSLS+++    
Sbjct: 531 IDRMFAKYAPATFLSLFIDDCIAKGKDYYNCGPRYNTTYIQCTGLGTITDSLSSLRKHVF 590

Query: 546 KP---IRDEDGLAIDFEIEGE----------YPQFGNNDPRVDDLAVDLVERFMKKIQKL 592
           +      +    A+    EG            P FGN+DP  D +AV + +     I+  
Sbjct: 591 EDKTFTMEALLDAMADNFEGHEPMRQMILNRTPFFGNDDPYADQIAVRVFDDLYDAIEGK 650

Query: 593 HTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSV 652
              +      ++L+ T +V +GK  G TP+GR AG     G +P HG D  G  A + S+
Sbjct: 651 PNTKGECFHLNMLSTTCHVYFGKVMGATPNGRLAGRAISDGTSPSHGADIHGPSAVIKSL 710

Query: 653 AKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMN 712
            KL       G       +P+ L +++++ K  LA L+  YF       GG H+  N+++
Sbjct: 711 GKLDQVK-SGGTLLNQRFLPSLLWREEDISK--LASLIRSYFAL-----GGHHIQFNIVD 762

Query: 713 REMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQSM 760
            E L  A + PE Y  L +RV+GY+  FN +  + Q DVI RT  ++ 
Sbjct: 763 TETLYAAQKCPEDYRDLLVRVAGYSDYFNDMNADLQADVIARTEQETF 810


>UniRef50_P32674 Formate acetyltransferase 2 n=80 Tax=Gammaproteobacteria
           RepID=PFLD_ECOLI
          Length = 765

 Score =  652 bits (1682), Expect = 0.0,   Method: Composition-based stats.
 Identities = 155/763 (20%), Positives = 294/763 (38%), Gaps = 90/763 (11%)

Query: 61  GVKLENRTHA--PVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPF-GGIK 117
                 +T     +       + I  H    I +  E I G +T  P    + P      
Sbjct: 27  YTASHRQTEGEPVILRRAKATAYILEHVEISI-RDEELIAGNRTVKPRAGIMSPEMDPYW 85

Query: 118 MIEGSCKAYNRELDPMI----------KKIFTEYRK-THNQGVFDVYTPDILRCRKSGVL 166
           +++   +   R  D             +++F  + K +    +    T ++     + + 
Sbjct: 86  LLKELDQFPTRPQDRFAISEEDKRIYREELFPYWEKRSMKDFINGQMTDEVKAATNTQIF 145

Query: 167 TGLPDAYGRGRIIGDYRRVALYGIDYLMK----------DKLAQFTSLQADLENGVNLEQ 216
           +      G+G II DY R+  +G+  L+           +      +L     +  ++ +
Sbjct: 146 SINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHCQQQPENHFYQAALLLLEASQKHILR 205

Query: 217 TIRLREEIA---EQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGA 273
              L E +A      +   ++  +A    ++         +A Q  ++  +      N +
Sbjct: 206 YAELAETMAANCTDAQRREELLTIAEISRHNAQHKPQTFWQACQLFWYMNIILQYESNAS 265

Query: 274 AMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPI 333
           ++S GR   ++  + +  L  G+      +E+++ L +K   +  LR+      F+G P 
Sbjct: 266 SLSLGRFDQYMLPFYQTSLTQGE-DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPT 324

Query: 334 WATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAK-VS 392
             T  +GG+  +GR+ V   SF  L+   ++   P+PN+ +  +  +   F    A+ + 
Sbjct: 325 GYTALLGGLTENGRSAVNVLSFLCLDAYQSV-QLPQPNLGVRTNALIDTPFLMKTAETIR 383

Query: 393 IDTSSLQYENDDLMRPDF--------NNDDYAIACCVSPMIVGKQMQFFG-ARANLAKTM 443
             T   Q  ND+++ P F        +  DY++  CV   I G+       A  NL K M
Sbjct: 384 FGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCVELSIPGRTYGLHDIAMFNLLKVM 443

Query: 444 LYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHD 503
              ++                      L Y+ ++E++   +       +   NI    H 
Sbjct: 444 EICLHE---------------NEGNAALTYEGLLEQIRAKISHYITLMVEGSNICDIGHR 488

Query: 504 KYSYEASLMALHDRDVIRTMAC------------GIAGLSVAADSLSAIKYAKVK---PI 548
            ++    L +     + +                   G++  +DSL A+K    +     
Sbjct: 489 DWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGMVFEQQRLS 548

Query: 549 RDED------------GLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYR 596
            DE             G  +   +   + ++GN+   VD+++ +L+  + K+++K    R
Sbjct: 549 FDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPR 608

Query: 597 DAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGP-GANPMHGRDQKGAVASLTSVAKL 655
               T    T++++V  G   G TPDGR AG      G +PM G+D +G  A L SV+KL
Sbjct: 609 GGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKL 668

Query: 656 PFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREM 715
                 +G        P  L  +  +RK  LA  +  +   +      QH+  NV+N + 
Sbjct: 669 DNTLLSNGTLLNVKFTPATLEGEAGLRK--LADFLRAFTQLKL-----QHIQFNVVNADT 721

Query: 716 LLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQ 758
           L +A + P+ Y  L +RV+GY+  F  L+KE Q D+I RT  Q
Sbjct: 722 LREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQ 764


>UniRef50_B6FX97 Putative uncharacterized protein n=4 Tax=Firmicutes
           RepID=B6FX97_9CLOT
          Length = 796

 Score =  651 bits (1679), Expect = 0.0,   Method: Composition-based stats.
 Identities = 156/768 (20%), Positives = 296/768 (38%), Gaps = 80/768 (10%)

Query: 58  VMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIK 117
           +    K             ++ +++   + G   ++ E IVG +T+      + P  G  
Sbjct: 40  ITRVYKENEELSTSKKRALSLKASLEELEIG--VEKEELIVGNRTKGVRYGVVFPESGCS 97

Query: 118 MI-EGSCKAYNRELDPMIKK----------IFTEYR-KTHNQGVFDVYTPDILRCRKSGV 165
            + +       R  D  + K          I+  +  K+    + + Y  +I     + V
Sbjct: 98  WVNKEFETLPTRPQDKFLVKEEDIKEFRESIYPYWNGKSMEDVIKNNYGKEINAM--AKV 155

Query: 166 LTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFT-------------------SLQA 206
           +      + +G I  D       G   L+     +                     +   
Sbjct: 156 VKINQKDHAQGHICPDSELWLKLGPQGLIDKAREKMANCEENQKEFYECTILVLEGAKNF 215

Query: 207 DLENGVNLEQTIRLREEIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAA 266
            +     +   I    +   +      ++ +A         P     EA+Q  +F +   
Sbjct: 216 MMRYHDYILNMINNCGDDKIEDEYKESLRNVAEICKNLSERPPKTFHEAVQSLWFLFTIL 275

Query: 267 VKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDE 326
               N ++ S GR   +L  Y + D++ G I+EQ+A E+++ L +K   + +LR     +
Sbjct: 276 HMESNASSFSPGRMDQYLYPYYKEDIEKGIISEQDALEIIECLWLKFNQIVYLRNQHSAK 335

Query: 327 LFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKK 386
            F+G PI    +IGG+  +G  +    S   L   Y +G  P+PN+++  ++       +
Sbjct: 336 YFAGFPIGFNIAIGGVDENGDDIYNNLSLLILRAQYHLG-LPQPNLSVRLNKNTSHELMQ 394

Query: 387 FAAK-VSIDTSSLQYENDDLMRPDF--------NNDDYAIACCVSPMIVGKQMQFFG-AR 436
            + K V+  +   Q+ ND+ +            +  +YA+  CV     G  + +   A 
Sbjct: 395 ESIKVVAKGSGMPQFFNDESIIKAMIDLGIEEKDARNYAVVGCVELTTHGNNLGWSDAAM 454

Query: 437 ANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALN 496
            NL K +   +N G       Q+G     ++ D   ++++ E     +D+   + + A  
Sbjct: 455 FNLNKALELTLNEGKCLLTGEQIGLNLGKLE-DYKTFEDLEESFRKQIDYFINEMMKAEV 513

Query: 497 IIHYMHDKYSYEASLMALHDRDVIRTMACGIAG------------LSVAADSLSAIKYAK 544
           ++   H      A L  + D  + + +     G            ++  ADSL+AIK   
Sbjct: 514 VVEKAHQDCLPSAFLSTVIDDCLEKGLDVTRGGAKYNLSGIQMIQVANLADSLAAIKELV 573

Query: 545 VKPIR---DEDGLAIDFEIEGE----------YPQFGNNDPRVDDLAVDLVERFMKKIQK 591
                   +E   A+  + +G            P++GN+   VDDL       F ++++ 
Sbjct: 574 YDEEMISKEELLQALRDDFKGHEITQTMLLNKAPKYGNDVKWVDDLGTKWAGYFRERMKD 633

Query: 592 LHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGP-GANPMHGRDQKGAVASLT 650
              YR       + T++++V  G+  G +PDGR A  P    G +P++GRD  G  A + 
Sbjct: 634 YTNYRGGAYHTGMYTVSAHVPMGENVGASPDGRNALTPLADGGMSPVYGRDIAGPTAVIK 693

Query: 651 SVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNV 710
           SV+++   Y  +G       +P     +  + K      +  +   E       H+  NV
Sbjct: 694 SVSRISNDYTTNGGLLNMKFLPEFFKTETGMLK--FESFLRAFVDLEVP-----HIQFNV 746

Query: 711 MNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQ 758
           + RE LLDA  +PE++  LTIRV+GY   F  L  + Q ++I RT  +
Sbjct: 747 VRREDLLDAKVHPERHKSLTIRVAGYTAYFVELAGKLQDEIIERTAYE 794


>UniRef50_C6A251 Pyruvate-formate lyase n=50 Tax=cellular organisms
           RepID=C6A251_THESM
          Length = 823

 Score =  645 bits (1664), Expect = 0.0,   Method: Composition-based stats.
 Identities = 164/775 (21%), Positives = 311/775 (40%), Gaps = 83/775 (10%)

Query: 58  VMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIK 117
           + E  K E      +    A+A            ++ + IVGL+     +    P   + 
Sbjct: 60  ITEFYKSEIPKGKSIPVQRALAFKYLLEHCSLPIEEGQLIVGLRGTGVKEVPTYPEICVH 119

Query: 118 MIEGSCKAYNRELDPMIK----------KIFTEYR-KTHNQGVFDVYTPDILRCRKSGVL 166
            +E      +R+  P             +I   ++ +     +F+    + +   ++G+ 
Sbjct: 120 SMEDLEILNSRQNMPYKVDEETRELYKNEIIPFWKGRAMRDMIFETLPQEWIDAYEAGIW 179

Query: 167 TGLPDAYGRGRIIGDYRRVALYGIDYLMKD-----------------KLAQFTSLQADLE 209
           T   +    G   G   R+   G+  + ++                 K+ +  ++    E
Sbjct: 180 TEFMEQRSPGHTAGG-GRIFRMGVLDIKEEIKKKMGELDPSNPEYYEKMEELKAMDIVAE 238

Query: 210 N-GVNLEQTIRLREEIAEQHR---ALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLA 265
              +  ++     E++AE+ +      ++K+MA       +       EA+Q  +F ++ 
Sbjct: 239 AILIYAKRYAEKLEKMAEEEKDPKRKKELKQMAEICKRVPAHAPRTFWEALQHYWFVHVG 298

Query: 266 AVKSQNG-AAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFL-RTPE 323
                N   + + GR    L  + +RDL+ G++T ++A+E++    +K      + +   
Sbjct: 299 VTYETNPWDSFNPGRIDQHLYPFYKRDLEEGRLTREKAKELLQCFWLKFNNQPAVPKVGV 358

Query: 324 YDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLN 383
             E       ++  ++GG+  DG   V + S+  L  L  M  + +PN  +L S K P  
Sbjct: 359 TAEESFTYNDFSKLNLGGLKKDGSDGVNELSYLILEVLSEM-RTLQPNTAVLISNKNPDR 417

Query: 384 FKKFAAKV-SIDTSSLQYEN-DDLMRPDF-------NNDDYAIACCVSPMIVGKQMQFFG 434
           F   A KV         + N D ++           +     ++ CV     GK+     
Sbjct: 418 FLIEALKVVGPGFGEPPFFNFDGVIVKMLRQGKTLEDARTSGVSGCVETGAFGKEAYILT 477

Query: 435 ARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITA 494
              NL K +   +N G+D +   ++G ++   +    +++E+       ++      +  
Sbjct: 478 GYFNLPKILGITLNNGIDPRTGKKIGIETGDPRN-FKSFEELWNAFVKQVNHFLDIKMKG 536

Query: 495 LNIIHYMHDKYSYEASLMALHDRDV------------IRTMACGIAGLSVAADSLSAIKY 542
            +II  ++ KY     +    +  V              T    + GL   ADSL+AIKY
Sbjct: 537 NDIIETLYAKYLPVPFMSLWIEDCVKNAKDYNGGGTRYNTQYIQVVGLGTIADSLAAIKY 596

Query: 543 AKVK---PIRDEDGLAIDFEIEG------------EYPQFGNNDPRVDDLAVDLVERFMK 587
                   + +E   A+    +G            + P+FGN+D  VD++A  +V+  + 
Sbjct: 597 HVFDKKTFVMEELLNALKNNWKGYEMMREILRNPEKTPKFGNDDEYVDEIAKKVVDTVVD 656

Query: 588 KIQKLHTY--RDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGA 645
            I+       R A      L  T +V +GK TG TPDGR AG P   G +P+ G D+KG 
Sbjct: 657 LIEAYPPSPVRKASKRAYFLPTTVHVYFGKVTGATPDGRDAGFPVSEGISPVQGMDRKGI 716

Query: 646 VASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQH 705
            A   SVAK  +     G      + P+    ++ ++K  LA L+  +F       GG H
Sbjct: 717 AAVFRSVAKCDWDK-TGGALLNQKLTPDLFDNEENIKK--LAQLIRTFFRL-----GGHH 768

Query: 706 LNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQSM 760
           +  NV++ E+L +A + P+++  L +RV+GY+  F +L K  Q ++I RT  + +
Sbjct: 769 VQFNVISAELLREAQKRPQEFQDLMVRVAGYSDYFVNLPKGLQDEIIARTEHKKV 823


>UniRef50_B5XXR3 Formate C-acetyltransferase 2 n=9 Tax=cellular organisms
           RepID=B5XXR3_KLEP3
          Length = 765

 Score =  645 bits (1664), Expect = 0.0,   Method: Composition-based stats.
 Identities = 156/731 (21%), Positives = 293/731 (40%), Gaps = 87/731 (11%)

Query: 91  NKQLEKIVGLQTEAPLKRALIPF-GGIKMIEGSCKAYNRELDPMI----------KKIFT 139
            ++ E I G +T  P    + P      ++        R  D             + ++ 
Sbjct: 58  IREDELIAGNRTVKPRAGIMSPEMDPYWLLNELDAFPTRPQDRFAISEEDKQIYREALYP 117

Query: 140 EYRK-THNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKD-- 196
            + K +    +    T ++     + + +      G+G II DY R+  +G+  L+ +  
Sbjct: 118 YWEKRSMKDFINGQMTEEVKAAVNTQIFSVNQTDKGQGHIIIDYPRLLNHGLGALVAELK 177

Query: 197 ----KLAQFTSLQADL----ENGVNLEQTIRLREEIA---EQHRALGQMKEMAAKYGYDI 245
               +  +    QA L     +  ++ +   L EE+A   +  +   ++  +AA   ++ 
Sbjct: 178 THCARQPENPFYQAVLILLEASQRHILRYAALAEEMAGHFQDPQRQQELLTIAAISRHNA 237

Query: 246 SGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEM 305
               T+  +A Q  ++  +      N +++S GR   ++  + +  L  G+      +E+
Sbjct: 238 QHRPTDFPQACQLFWYMNIILQYESNASSISLGRFDQYMLPFYQASLNQGQ-DPAYLKEL 296

Query: 306 VDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMG 365
           ++ L +K   +  LR+      F+G P   T  +GG+   GR+ V + SF  L+    + 
Sbjct: 297 LESLWVKCNDIVLLRSSSSARYFAGFPTGYTALLGGLTDTGRSAVNELSFLCLDAYQNV- 355

Query: 366 PSPEPNMTILWSEKLPLNFKKFAAK-VSIDTSSLQYENDDLMRPDF--------NNDDYA 416
             P+PN+ +  +E +   F +  A+ + + T   Q  ND+++ P F        +  DYA
Sbjct: 356 QLPQPNLGVRVNELIDRPFLRKTAETIRLGTGIPQIFNDEVVVPAFLNRGVSLEDARDYA 415

Query: 417 IACCVSPMIVGKQMQFFG-ARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDE 475
           +  CV   I G+       A  NL K M   +     +                 + +D 
Sbjct: 416 VVGCVELSIPGRTYGLHDIAMFNLLKVMEIVLQENEHQPD---------------VTWDG 460

Query: 476 VMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMAC---------- 525
           ++ ++   +    K  +   NI    H  ++    L +  +  V                
Sbjct: 461 LICQIRDKIRHYIKLMVEGSNICDIGHRDWAPVPLLSSFIEDCVQHGKDITAGGARYNFS 520

Query: 526 --GIAGLSVAADSLSAIKYAKVK---PIRDED------------GLAIDFEIEGEYPQFG 568
                G++  +DSL A+K           D+             G  I   +   + ++G
Sbjct: 521 GVQGIGIANLSDSLYALKGMVFDQQRLSFDQLMAVLKANFQTPEGEKIRARLINHFDKYG 580

Query: 569 NNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGA 628
           N+   VD+++ DL+  + K++++    R    T    T++++V  G   G TPDGR AG 
Sbjct: 581 NDIDDVDNISADLLRFYCKEVEQYLNPRGGHFTPGSYTVSAHVPLGSVVGATPDGRLAGE 640

Query: 629 PFGP-GANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLA 687
                G +PM G+D +G  A L SV+KL      +G        P  L  D  + K  LA
Sbjct: 641 QLADGGLSPMVGQDSQGPTAVLKSVSKLDNYLLSNGTLLNVKFTPATLAGDGGLNK--LA 698

Query: 688 GLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQ 747
             +  +   +      QH+  NV+N + L +A + P+ +  L +RV+GY+  F  L+KE 
Sbjct: 699 DFLQAFCKLKL-----QHIQFNVVNADTLREAQQRPQDFAGLVVRVAGYSAFFVELSKEI 753

Query: 748 QQDVITRTFTQ 758
           Q D+I RT  Q
Sbjct: 754 QDDIIRRTAHQ 764


>UniRef50_B4U135 Pyruvate formate-lyase n=65 Tax=Bacilli RepID=B4U135_STREM
          Length = 795

 Score =  642 bits (1656), Expect = 0.0,   Method: Composition-based stats.
 Identities = 331/772 (42%), Positives = 456/772 (59%), Gaps = 35/772 (4%)

Query: 6   EKLATAWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLWDKVMEGVKLE 65
           +    AWEGF   DW+ + ++  F+Q NYTPY+GDESFLAG TE +  +   + E     
Sbjct: 30  DVFEKAWEGFKGTDWKEKASISRFVQANYTPYDGDESFLAGVTERSLHIKKIIEETKAHY 89

Query: 66  NRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIKMIEGSCKA 125
             T  P D      ++I    AG+I+K  E I G+Q +   K   +P GGI+M E + K 
Sbjct: 90  EATRFPYD---TRPTSIADIPAGFIDKDKELIFGIQNDELFKLNFMPKGGIRMAETTLKE 146

Query: 126 YNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRV 185
              E DP + +IFT++  T N G+F  YT +I R R +  +TGLPDAY RGRIIG Y R+
Sbjct: 147 NGYEPDPAVHEIFTKHVTTVNDGIFRAYTSNIRRARHAHTVTGLPDAYSRGRIIGVYARL 206

Query: 186 ALYGIDYLMKDKLAQFTSLQADLENGVNLEQTIRLREEIAEQHRALGQMKEMAAKYGYDI 245
           ALYG DYLM++K+  + ++    E        IRLREEI  Q++ALG++ ++   YG D+
Sbjct: 207 ALYGADYLMQEKVNDWNAITEIDEES------IRLREEINLQYQALGEVVKLGDLYGVDV 260

Query: 246 SGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEM 305
             PA N +EAIQW    ++A  +  NGAA S GR    LD++ ERDL  G  TE E QE 
Sbjct: 261 RRPAENVKEAIQWVNIAFMAVCRVINGAATSLGRVPIVLDIFAERDLARGTFTESEIQEF 320

Query: 306 VDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMG 365
           VD  V+KLR V+F RT  YD L+SGDP + T S+ GMG DGR  VTK  +RFLNTL  +G
Sbjct: 321 VDDFVLKLRTVKFARTKAYDALYSGDPTFITTSMAGMGNDGRHRVTKMDYRFLNTLDNIG 380

Query: 366 PSPEPNMTILWSEKLPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNNDDYAIACCVSPMI 425
            SPEPN+T+LW++KLP  F+++   +S   SS+QYE    M  D   +   I+CCVSP+ 
Sbjct: 381 NSPEPNLTVLWTDKLPYAFRRYCMHMSHKHSSIQYEGVTTMAKDGYGEMSCISCCVSPLD 440

Query: 426 VGKQM-----QFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERM 480
              +      Q+FGAR N+ K +L  +NGG D+  K       +P+  DVL++D V    
Sbjct: 441 PENEEQRHNIQYFGARVNVLKALLTGLNGGYDDVHKDYKVFDIDPVTDDVLDFDTVKANF 500

Query: 481 DHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVAADSLSAI 540
           +  +DWL   Y+ ALNIIHYM DKY+YEA  MA         M  GI G +   D+LSAI
Sbjct: 501 EKSLDWLTDTYVDALNIIHYMTDKYNYEAVQMAFLPSHQRANMGFGICGFANTVDTLSAI 560

Query: 541 KYAKVKPIRDEDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIP 600
           KYA VKPIRDEDG   D+E  G+YP++G +DPR ++LA  L+E +  +++    Y++A  
Sbjct: 561 KYATVKPIRDEDGYIYDYETIGDYPRWGEDDPRSNELAEWLIEAYTTRLRSHKLYKNAEA 620

Query: 601 TQSVLTITSNVVYGKKTGNTP---------DGRRA---GAPFGPGANPMHGRDQKGAVAS 648
           T S+LTITSNV Y K+TGN+P         DG         F PGANP + + + G + +
Sbjct: 621 TVSLLTITSNVAYSKQTGNSPVHRGVYLNEDGTTNLSQLEFFSPGANPSN-KAKGGWLQN 679

Query: 649 LTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNV 708
           L S+A L F+YA DGIS T  + P ALGK  + +  NL  ++DGYF +     GGQH+N+
Sbjct: 680 LNSLASLDFSYAADGISLTTQVSPRALGKTHDEQVENLVTILDGYFEN-----GGQHVNL 734

Query: 709 NVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQSM 760
           NVM+   + D +   E    + +R+SGY V    LT EQ+ ++  R F + +
Sbjct: 735 NVMDLNDVYDKIMAGE---DVIVRISGYCVNTKYLTPEQKTELTQRVFHEVL 783


>UniRef50_B6FJR9 Putative uncharacterized protein n=1 Tax=Clostridium nexile DSM
           1787 RepID=B6FJR9_9CLOT
          Length = 794

 Score =  641 bits (1654), Expect = 0.0,   Method: Composition-based stats.
 Identities = 162/740 (21%), Positives = 286/740 (38%), Gaps = 85/740 (11%)

Query: 93  QLEKIVGLQTEAPLKRALIPFGGIKMI-EGSCKAYNRELDPMIKKIFTEYRKTHNQGVFD 151
             E IVG          L       ++ +       R+ DP I K   E R+     V  
Sbjct: 64  DQELIVGCAGSKMRGGILSADTCWSILDKELDTINERKYDPFILK--PEDRQMFLDVVKP 121

Query: 152 VY-------------TPDILRCRKSGVLTGLPD-AYGRGRIIGDYRRVALYGIDYLMKDK 197
            +               D+   R SG +        G G     Y+++   GI+ +M   
Sbjct: 122 FWEGRSTYEAWLKQIPDDVRALRDSGQIYIDKKAVRGWGETTAGYKQIIDEGIESIMNTI 181

Query: 198 LAQFTSLQADLENG------------------VNLEQTIRLREEIAE---QHRALGQMKE 236
            A+  +L                         +  E+  +  E +AE         ++  
Sbjct: 182 KAEREALDLTDPGAFDKDNYLQALLISAEGICIMAERYAKEAERLAELEKDEERKAELLT 241

Query: 237 MAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGK 296
           +A    +    PA   QEAIQ  YF +++    QN AA + GR   +   Y + D+++G+
Sbjct: 242 IAETCHHVPRYPARTFQEAIQSFYFYHISIFMEQNAAAYNPGRMDQYFYPYYKVDIESGR 301

Query: 297 ITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFR 356
           ITE E QE+++ L +K       +        +G P++ T   GG+  +GR  V   S+ 
Sbjct: 302 ITEDEGQELLECLWVKFSEPCVFQDATTARYSAGYPMFQTLCCGGIDAEGRDAVNDISYM 361

Query: 357 FLNTLYTMGPSPEPNMTILWS-EKLPLNFKKFAAK-VSIDTSSLQYENDDLMRPDFN--- 411
            L     +    +PNM + +S  K P  F K  A+ +S+ T    + NDD+         
Sbjct: 362 MLQATQDVL-LYQPNMCVRYSMAKNPTKFLKKVAEVISLGTGFPAFYNDDVGIRMLMNKG 420

Query: 412 -----NDDYAIACCVSPMIVGKQMQFFG-ARANLAKTMLYAINGGVDEKLKMQVGPKSEP 465
                  D+  A CV   + G+   +   A  NL   + +A+  GV+ K   +V  ++  
Sbjct: 421 IPLKEAYDWNPAGCVETNLDGRLRHYSAFADINLGGIIEFALTNGVNRKTGRKVATETGD 480

Query: 466 IKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIR---- 521
                  Y++    +   + +  +  +   +II  +        +L       V      
Sbjct: 481 PTT-FETYEDFENAVKEQLKYSVRICVKGSHIIDDICMDRI-VPALSLSFRECVKNAKDY 538

Query: 522 ---------TMACGIAGLSVAADSLSAIKYAKVKP---IRDEDGLAIDFEIEG------- 562
                         + G++   +S+ AI+           ++   A+D + EG       
Sbjct: 539 AWGGAKYNTGNGIILIGVADLINSMEAIRDLVYDRKLVSMEDMVKALDADFEGYEEIQKL 598

Query: 563 --EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNT 620
             E  ++GN+D  V+D+   ++     +I+K H+      T  +L ++ N  +G+  G  
Sbjct: 599 CKESHKYGNDDDDVNDITSHMLTFIADEIEKYHSKFG-QMTPGILPVSGNTPFGQDVGAL 657

Query: 621 PDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDE 680
           P GR+A  P   G +P  G D +G  A + SVA +P +    G      + P+ +  ++ 
Sbjct: 658 PSGRKAWMPLADGISPNGGTDVEGPAAVIKSVASIPHSRYTQGTLLNMKLEPDMVKTENG 717

Query: 681 VRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRF 740
           +R   L  L+      +       H+  NV+++E LL A + PE Y  L +RV+GY   F
Sbjct: 718 IR--QLMALLRSLCTLDV-----YHVQFNVIDKETLLAAQKKPENYKGLLVRVAGYTAYF 770

Query: 741 NSLTKEQQQDVITRTFTQSM 760
             L +E Q ++I RT   + 
Sbjct: 771 TELGREVQDEIIARTAQSNF 790


>UniRef50_A6TKL5 Pyruvate formate-lyase n=1 Tax=Alkaliphilus metalliredigens QYMF
           RepID=A6TKL5_ALKMQ
          Length = 806

 Score =  641 bits (1653), Expect = 0.0,   Method: Composition-based stats.
 Identities = 170/740 (22%), Positives = 294/740 (39%), Gaps = 80/740 (10%)

Query: 93  QLEKIVGLQTEA-PLKRALIPFGGIKMIEGSCKAY--NRELDPM---------IKKIFTE 140
           + E IVG           + P    K +E         R  D           +K IF  
Sbjct: 75  EGELIVGSHGSNGRRSAPVFPEFSTKWLEEELDEILETRTQDTFIVPKNVKEDLKDIFPY 134

Query: 141 YR-KTHNQGVFDVYTPDILRCRKSGVLT-GLPDAYGRGRIIGDYRRVALYGIDYLMKDKL 198
           +R KT +     +   +  R R + + T GL +  G G    D  ++   G+  +  +  
Sbjct: 135 WRGKTIHDRYRAMLPDETKRARDAYMFTRGLFEQNGYGHTAYDIPKLLKVGLVGIKSEVN 194

Query: 199 AQFTSLQADLENG------------------VNLEQTIRLREEIAEQHR---ALGQMKEM 237
            +  +L      G                     ++  +   E+A+Q +      +++++
Sbjct: 195 EKMQTLDLTTSEGLEKKLFYEGLIVCCDSVIAYAKRYAQRALELADQEKNPVRKKELEKI 254

Query: 238 AAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKI 297
           A    +    PA +  +AIQ   F  L      NG ++  GR   +L  Y + D+  G+ 
Sbjct: 255 ADVCQWVPENPARDTWDAIQVVAFMQLIIQTETNGDSVCPGRLDQYLYSYYKNDMAEGRY 314

Query: 298 TEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRF 357
           T  E QE++D L +KL  +  ++  E   +  G P+  T +IGG   +G     + S+  
Sbjct: 315 TIDEIQELLDCLWIKLNEIIKIQASESVRIHPGFPMTPTVTIGGQTPEGEDATNELSYLM 374

Query: 358 LNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAK-VSIDTSSLQYENDDLMR--------- 407
           LN+   +     P  T+ + +  P +FK    + V + T       D+            
Sbjct: 375 LNSQEHI-RLTNPQFTVRFHKDTPEDFKLRVVEVVKLGTGMPAMFGDEACIAALKRGCPD 433

Query: 408 -PDFNNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPI 466
            P     DY I  CV     G Q +  G   N+A+ +  A+N GVD     Q+GP++   
Sbjct: 434 MPMERIRDYRIVGCVELAPRGFQGRVNGGFLNVARVVDLALNNGVDRLTNEQIGPQTGAP 493

Query: 467 KGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMA-- 524
           + D+ ++D+V+  +     +  K  +    ++  +  +++    L +L +  +       
Sbjct: 494 E-DLKDFDDVLTAVRTQTAYFVKHQVINAAVVDMVQREHTPHLFLSSLVEGCIENGKDMT 552

Query: 525 ----------CGIAGLSVAADSLSAIKYAKVKP---IRDEDGLAIDFEIEGEY------- 564
                         G + AADSL  +K A          E    +D    G         
Sbjct: 553 QGGSLWGGTPILHVGEATAADSLIGVKKAVFDDQLISMKELKEILDSNFAGAQGEKIYQA 612

Query: 565 ----PQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNT 620
               P++GN+D   D++   ++  F  +I+K         T ++LT+ + V +G  TG T
Sbjct: 613 LLAMPKYGNDDDYADEVMQKMINIFFDEIEKHKDIDGRFYTSTILTLGATVPHGWTTGAT 672

Query: 621 PDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDE 680
            +GR+A  P     +  +G D++G  A L S +K+      +G          AL  +++
Sbjct: 673 ANGRKATMPVADSMSASNGADKEGPTAMLLSASKIDQTRTIEGNVVNLKFTKMAL--EEK 730

Query: 681 VRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRF 740
                L  L+  YF        GQ + VNV++   L DA E PEK+  L IRV+GY+ RF
Sbjct: 731 KNLQQLVNLVSVYFDDLK----GQEIQVNVVDESTLKDAQEYPEKHQDLIIRVAGYSARF 786

Query: 741 NSLTKEQQQDVITRTFTQSM 760
             L KE Q D+I RT   ++
Sbjct: 787 TELAKELQDDIIRRTEYNTL 806


>UniRef50_A6TPN1 Formate C-acetyltransferase n=3 Tax=Clostridiaceae
           RepID=A6TPN1_ALKMQ
          Length = 789

 Score =  638 bits (1645), Expect = 0.0,   Method: Composition-based stats.
 Identities = 154/736 (20%), Positives = 272/736 (36%), Gaps = 79/736 (10%)

Query: 94  LEKIVGLQTEAPLKRALIPFGGIKMIE-GSCKAYNRELDPMI----------KKIFTEYR 142
            E IVG   E      L P      ++        R  DP +          KKIF  ++
Sbjct: 62  EELIVGSIGEFRKCGILTPEFSWTWVDREMDNFDERVQDPYVMTDEQRTFVRKKIFPYWK 121

Query: 143 KTHNQGVFDVYTPD--ILRCRKSGVLTGLPDAY-GRGRIIGDYRRVA-LYGIDYLMKDKL 198
               +  F    P+        +G++          G +  DY+ V    G   ++K+  
Sbjct: 122 GKSLEEAFLAQLPEKTAKVAVDTGIVDNDSKWRQAVGEMTPDYQDVLFKKGFGGIIKEAK 181

Query: 199 AQFTSLQ----ADLENGVNL-------EQTIRLREE----------IAEQHRALGQMKEM 237
                L      D++            E  I L             I       G++ ++
Sbjct: 182 EHIIKLSLTSAEDMKKKDFYNSIIITSEGMITLANRYGQKATEMADIENNPIRKGELLKI 241

Query: 238 AAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKI 297
           A   G     P     EAIQ+ +F  +  + S+N  A++ GR   F+  Y + D+  G I
Sbjct: 242 ADICGRIPENPPDTFYEAIQFVWFTQVGGIISENPLALNIGRFDQFMYPYYKSDVDKGII 301

Query: 298 TEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRF 357
           T+ EAQE+++ L +KL    +  +    E F+G   +   ++GG   +G+      S+  
Sbjct: 302 TKDEAQELIEALWIKLSEWVWTISANTAEFFAGYNQFQNLTVGGKTREGKDATNDLSYMC 361

Query: 358 LNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAK-VSIDTSSLQYENDDLMRPDF------ 410
           L     +  + +P +++   +  P +F       VS  T      ND             
Sbjct: 362 LKATERV-KTHQPGLSVRVHQDSPRSFLDAVTHLVSKGTGFPAIHNDTAGYQMLINAGYE 420

Query: 411 --NNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKG 468
             +  D+    CV P              N    + +A+N G       ++G   +    
Sbjct: 421 PEDARDWNNCGCVVPHFRKTGEWTSAVNINFTAALEFALNQGESRITGEKIGMDEDKPTT 480

Query: 469 DVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMA---- 524
              +Y+EV +      D L +  I A  +   +H +      L +  +  +I+       
Sbjct: 481 -FQSYEEVEKAFYKQFDNLIEHSIIATLLAQKLHKEMVPRPFLSSCIEECMIKGKDLVDA 539

Query: 525 ---------CGIAGLSVAADSLSAIKYAKVKP---IRDEDGLAIDFEIEG---------E 563
                        GL+V ++SL+ IK    +      +    A+D   EG          
Sbjct: 540 GAKYNLGPVLTGIGLAVTSNSLAVIKKLVFEDKMTTMETLIKALDANWEGYEKLRQLAVS 599

Query: 564 YPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDG 623
            P++GNN   VDD+A+ +   + K+  K           + + I++ +  GK  G TP G
Sbjct: 600 VPKYGNNVDYVDDIAIKIANYYYKQGHKYKDINGNNFNTAFMGISNYLPTGKVVGATPCG 659

Query: 624 RRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRK 683
           R+A  P   G +P  G D    + ++ S AKL       G      +  + +        
Sbjct: 660 RKAKEPLSEGVSPFAGSDTSTPLEAMRSAAKLNQDVHSGGTLLNLRLNEDLVNTKRGQ-- 717

Query: 684 TNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSL 743
           +NL  ++  +F       G  H+  N ++ + L  A  NP+ Y  L +RV+GY+ +F +L
Sbjct: 718 SNLGFMIQSFFAL-----GAFHVQFNTISTDTLRKAQNNPQDYKDLLVRVAGYSTQFVNL 772

Query: 744 TKEQQQDVITRTFTQS 759
           +K  Q+ +I RT  ++
Sbjct: 773 SKSMQEAIIARTAHEN 788


>UniRef50_O28823 Pyruvate formate-lyase 2 (PflD) n=1 Tax=Archaeoglobus fulgidus
           RepID=O28823_ARCFU
          Length = 776

 Score =  637 bits (1643), Expect = 0.0,   Method: Composition-based stats.
 Identities = 154/761 (20%), Positives = 301/761 (39%), Gaps = 80/761 (10%)

Query: 59  MEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFG-GIK 117
            E +K        +         +  +    I    E IVG     P    + P G G++
Sbjct: 28  TESMKQTEGEPMII-RQAKALKHVLENIPIQIL-DSELIVGTMLPNPPGAIIFPEGVGLR 85

Query: 118 MIEGSCKAYNRELDPMI----------KKIFTEY-RKTHNQGVFDVYTPDILRCRKSGVL 166
           +I       NRE + ++          ++I   + RKT     F    PDI++   +G +
Sbjct: 86  IINELDSLPNRETNRLMVDEEDAKVLREEIAPYWQRKTIEAFAFP-LMPDIMQILYTGSV 144

Query: 167 TGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQAD-----------LENGVNLE 215
             L +  G   +  +Y  +   G  + +++   +  +L+                 +  E
Sbjct: 145 FVLTEIAGISHVAVNYPYLLRRGFRWFLEESERRIRALEESGVYEGEKYSFYQAAKIVSE 204

Query: 216 -------QTIRLREEIAEQH--RALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAA 266
                  +  +L EE+AE        ++ ++A       +       EA+Q+ +    A 
Sbjct: 205 AVINYGLRYSKLAEELAESEDGERREELLKIAEICRKVPAEKPETFWEAVQFVWLVQSAL 264

Query: 267 VKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDE 326
            +     A+S GR   +L  + ++D+  G+I  + A +++ +L +K   +        ++
Sbjct: 265 HQENYEQAISMGRIDQYLYPFFKKDIGEGRINRELAFDILANLWIKTNEIVPAFDSLLEQ 324

Query: 327 LFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKK 386
            FSG       +IGG  + G     + ++  L     +    +PN+ +  ++  P +F K
Sbjct: 325 YFSGQATNQAVTIGGCDIYGNDATNELTYLMLEVTDRL-RLRQPNVHVRINKGSPESFLK 383

Query: 387 FAAK-VSIDTSSLQYENDDLMRPDF--------NNDDYAIACCVSPMIVGKQMQFFG-AR 436
             A+ +S   ++L    DD              +  +Y    CV     G        A 
Sbjct: 384 RLAEAISSGCNNLALFFDDAAVKALKNAEVDDRDALNYTTDGCVEIAPFGNSFTSSDAAL 443

Query: 437 ANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALN 496
            N+AK + YA+N GVD +   + G K+E  K      ++++E++   +  + K  +   N
Sbjct: 444 INVAKALEYALNEGVDLQFGYEFGAKTEKPKF----LEDLLEKLREQVSHIVKLVVRGSN 499

Query: 497 IIHYMHDKYSYEASLMALHDRDVIRTM------------ACGIAGLSVAADSLSAIKYAK 544
           ++ Y + +      L    +    + +                 G++   DSL AI+ A 
Sbjct: 500 VLSYANAEVKPTPLLSLCVEDCFEKGVDVSRGGARYNFTGIQAVGIADVGDSLVAIEGAL 559

Query: 545 -VKPIRDEDGLAIDFEIEG---------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHT 594
                 D+   A      G         + P++GN+D   D     ++E + +++ +   
Sbjct: 560 NAGYSMDDIVEACRKNFVGYEKLHKLLLQSPKYGNDDDAADKYTKMVLEWYCEEVNRHRN 619

Query: 595 YRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAK 654
           +R          +T+NV +G  T   P GR++G P  PG +P  G D++G  A + S +K
Sbjct: 620 FRGGKFAAGCYPMTTNVGFGFFTSALPSGRKSGEPLNPGVSPSTGMDREGVTAVINSASK 679

Query: 655 LPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNRE 714
           L +    +G S T ++  + LG+  +     +  L+           G  H+  N++  +
Sbjct: 680 LSYENLPNGASLTINLSSDVLGEKGDA---VIEALIKSSMEL-----GVMHVQFNILKED 731

Query: 715 MLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRT 755
           +L  A + PEKY  L +RV+G++  F  L++  Q++VI R 
Sbjct: 732 LLRKAQQEPEKYRWLLVRVAGWSAYFVELSRPVQEEVIRRI 772


>UniRef50_A8ZW07 Formate C-acetyltransferase n=2 Tax=Proteobacteria
           RepID=A8ZW07_DESOH
          Length = 782

 Score =  635 bits (1637), Expect = e-180,   Method: Composition-based stats.
 Identities = 150/777 (19%), Positives = 280/777 (36%), Gaps = 77/777 (9%)

Query: 44  LAGATEATTTLWDKVMEGVKLENRTHAPVDFD-TAVASTITSHDAGYINKQLEKIVGLQT 102
           + G       LW       K       PV        S +  + + YI    E + G  T
Sbjct: 16  VPGVCPERALLW---TAYFKNRANRQKPVAVQIAGAVSHVLKNKSIYIYPD-EILAGNYT 71

Query: 103 EAPLKRALIPFG-GIKMIEGSCKAYNRELDPMIKKIFTEYR------KTHNQGVFDVYTP 155
              +   + P   GI ++    K + R L+P+       ++         N+ +     P
Sbjct: 72  SRRVGGIIYPESHGISVLMEIFKFHKRRLNPLETTPAHRWKLFATIPFWLNRNIIRKAFP 131

Query: 156 DILRCR--KSGVLTGLPDA----YGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLE 209
            I +      G LT          G   +  ++ ++   G++  +K+  A   +  A  +
Sbjct: 132 TIRQQLTFAVGQLTAREYQIYETGGISHLTPNHEKILAIGLEGFLKEIEAHEQAATAPEQ 191

Query: 210 N-------------GVNLEQTIRLREEIAEQHR---ALGQMKEMAAKYGYDISGPATNAQ 253
                             E+   L  ++A+          ++ +A          A    
Sbjct: 192 RDFYQAARIAAGGLIAFAERYADLARKMAKNEADPVRKADLERIADACKRVPRHGANTFF 251

Query: 254 EAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKL 313
           EA+Q     +++  +   G ++  GR    L  Y ++DL  G++T  +A+E++    +KL
Sbjct: 252 EAVQAMLLTHISLFQESLGESLCVGRMDQILWPYYQKDLSEGRLTRDQAKEILGAFCVKL 311

Query: 314 RMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMT 373
                       +   G   +   + GGM  +G     + S+  L  +  +    +PN  
Sbjct: 312 SETVPAYPEILAKTLGGLTSYQVVTTGGMDKNGEDATNELSYILLELMDEL-RMRQPNSH 370

Query: 374 ILWSEKLPLNFKKFAAKVSIDTSS-LQYENDDLMRPDF--------NNDDYAIACCVSPM 424
           +   +  P  F     +V+    S     ND+ +            +  +Y    CV P 
Sbjct: 371 VRIHKNTPKAFYDKVVEVTTGKGSAPALYNDETIIATMQKAGYTLADARNYVAIGCVEPT 430

Query: 425 IVGKQMQFFG-ARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHF 483
             GK +     A  N+   +  A+N G     + + G K+  +   +    +V +     
Sbjct: 431 SQGKTLGSTDAAIINMPLALELALNEGRRFGARRRTGAKTMAVL-QMRTMADVTDAYRTQ 489

Query: 484 MDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTM------------ACGIAGLS 531
           +     +    L  I   H  +        L D  + +                   G+S
Sbjct: 490 LRHQLGRLKNDLQAIEKAHAAFHPTPLTSMLIDGCLEKGKCSTSGGAVYNFSGIQGVGVS 549

Query: 532 VAADSLSAIKYAKVKPIRDEDGLAIDFEIEG-----------EYPQFGNNDPRVDDLAVD 580
              DSL A++    +         +D    G              +FGN+    D     
Sbjct: 550 TVGDSLYAVEKMVFEDRAMGLAELVDHLKSGLSNEAVRTRLRRLEKFGNDHAEADRWTRF 609

Query: 581 LVERFMKKIQKL-HTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHG 639
           +++ +   + ++  T R       + + T+++ +    G  P+GRR G PF  G  P +G
Sbjct: 610 VMDDYADAMAEMGQTTRGGRYNAGLYSNTTHIHFANFVGALPNGRRQGEPFASGIAPENG 669

Query: 640 RDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEAS 699
            D++G  A + S+ +L F    +GI++      NAL   D+  K  L  +   YF     
Sbjct: 670 MDRRGPTALVNSMNRLDFTRMANGINFNIKF--NALNMKDDAGKNALGSIFRVYFD---- 723

Query: 700 IEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTF 756
             GG  +  N+++ EML+ A +NP  +P L +RVSGY+  FN L+ E + ++I R+F
Sbjct: 724 -RGGMQVQANMLDPEMLMAARDNPSLHPHLLVRVSGYSAYFNDLSPEMKDEIIARSF 779


>UniRef50_C1N297 Predicted protein n=1 Tax=Micromonas pusilla CCMP1545
           RepID=C1N297_9CHLO
          Length = 776

 Score =  632 bits (1630), Expect = e-179,   Method: Composition-based stats.
 Identities = 385/772 (49%), Positives = 502/772 (65%), Gaps = 43/772 (5%)

Query: 23  EVNVRDFIQKNYTPYEGDESFLAGA----TEATTTLWDKVMEGVKLENRTHAPVDFDTAV 78
            ++V  F+  N TP + D S L GA    TE TT LW    E +  E      +  D   
Sbjct: 8   RLDVAAFVAANVTPCDDDLSKLPGALADATEKTTKLWSLCRELLTQEFDA-GVLAIDATT 66

Query: 79  ASTITSHDAGYINKQ---LEKIVGLQTEAPLKRALIPFGGIKMIEGSCKAYNRELDPMIK 135
            S++ SHDAGYI+      + + GLQT APL R + P GG+++++ +   +  ELD  + 
Sbjct: 67  PSSVLSHDAGYIDGDGVLDDVVPGLQTSAPLVRGIKPLGGMRLVKRALAEHGVELDADVA 126

Query: 136 KIFTE-YRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLM 194
             F   +R+THN  VFD+YT ++   R+  ++TGLPDAYGRGR+IGDYRRVALYG+D + 
Sbjct: 127 AFFDRGWRRTHNDCVFDLYTQEMRLARRHHLVTGLPDAYGRGRVIGDYRRVALYGVDAIA 186

Query: 195 KDKLAQFTSLQADLENGV---------NLEQTIRLREEIAEQHRALGQMKEMAAKYGYDI 245
           + K A    L  +  +           ++  T R R+E+A + +AL  +K MAA+YG D+
Sbjct: 187 ETKRADAARLAEEASSTAAAAAAGGDGDVSATFRRRDELALELKALEALKTMAARYGADV 246

Query: 246 SGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEM 305
           S PA+NA+EA++WTY  +LAA K  +GAA+S GR   F DVYIERDL+ G + E +AQE+
Sbjct: 247 SRPASNAREAVRWTYLAFLAACKENDGAAISLGRLDAFFDVYIERDLRGGVMDESDAQEL 306

Query: 306 VDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGR------------TLVTKN 353
           +DH V+KLR++R LR   YDE+F+GDP+WAT +I G    G              LVTK 
Sbjct: 307 IDHFVIKLRLIRQLRPKAYDEIFAGDPVWATCAIAGESSRGGGGGGAAAAAESRHLVTKT 366

Query: 354 SFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNND 413
           S+RF+ +L  +G +PEPNMT+LWS  LP  FK+  A+ SIDTSS+QY ND L+R  F +D
Sbjct: 367 SWRFMRSLANLGAAPEPNMTVLWSPTLPSGFKRQCARTSIDTSSVQYINDGLLRRAFKSD 426

Query: 414 DYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKS-------EPI 466
           D AIACCVS   +G   QFFGAR NLAK +L A+NGG++E    +V P S          
Sbjct: 427 DVAIACCVSGTRLGVDAQFFGARCNLAKLLLLALNGGLEELSGARVAPASIEASLGGGIA 486

Query: 467 KGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACG 526
               L YD+V  R+D +MDWLA  Y   + +IH+ HD+Y YEA++ +L D D    MA G
Sbjct: 487 PNVPLRYDDVRRRLDAYMDWLATLYRDVMALIHWSHDRYCYEAAIFSLIDTDRHYYMAYG 546

Query: 527 IAGLSVAADSLSAIKYAKVKPIRD-EDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERF 585
           +AGLSV  DSLSAIK+AKV P+ D E GL   FE EG +P +GN+D  VD +AVD+V  F
Sbjct: 547 VAGLSVVVDSLSAIKHAKVTPMLDAETGLIASFETEGTFPAYGNDDDAVDAIAVDVVTSF 606

Query: 586 MKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGA 645
           M K++ L  YRDA PT SVLTITSNV+YGK TG TPDGR AGAPF PGANPMHGRD  GA
Sbjct: 607 MNKLRALSQYRDAEPTLSVLTITSNVMYGKHTGATPDGRPAGAPFAPGANPMHGRDASGA 666

Query: 646 VASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQH 705
           ++SL SVAK+P+A+ KDGIS TFSI   +LGK  + R  NLA L+DGYF       G QH
Sbjct: 667 LSSLNSVAKVPYAHCKDGISNTFSIPGPSLGKTPDARVDNLAALLDGYFD-----RGAQH 721

Query: 706 LNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFT 757
           LNVNV++RE L+DAM +P KYP LT+RVSGYAV FN L++E Q++VI RTF 
Sbjct: 722 LNVNVLSRETLIDAMNDPMKYPNLTVRVSGYAVNFNRLSREHQEEVIARTFH 773


>UniRef50_D1ARQ1 Pyruvate formate-lyase n=3 Tax=Bacteria RepID=D1ARQ1_SEBTE
          Length = 807

 Score =  632 bits (1629), Expect = e-179,   Method: Composition-based stats.
 Identities = 171/775 (22%), Positives = 294/775 (37%), Gaps = 84/775 (10%)

Query: 56  DKVMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGG 115
           + + E  K        +         I S  + YI  +   I+G Q  +     + P   
Sbjct: 39  EIITESFKKTEGEPVVI-RRAKALDEILSKMSIYIE-EGMLIIGNQASSNFAAPIFPEYS 96

Query: 116 IKM-IEGSCKAYNRELDPM---------IKKIFTEYRK-THNQGVFDVYTPDILRCRKSG 164
               I    +   R  D           ++ +   ++  TH   V         +  + G
Sbjct: 97  FNWVINELDEFSKRSGDYFNITEETKDRLRVLQDYWQGITHQDNVLHNLPEINRKAEEQG 156

Query: 165 VLT-GLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLENGVNLE-------- 215
           VL  G     G G II ++  V   G   L +             E     E        
Sbjct: 157 VLHRGGISMSGDGHIIPNHDLVLAEGFGGLARIAEENSKREGLTQEQKDFYEAVKITMNA 216

Query: 216 ------QTIRLREEIAE---QHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAA 266
                 +   L    AE     +   ++K+++  + + + G A +  EA++  Y  +L  
Sbjct: 217 ALKYIKRFSELAAREAEKETDEKRKNELKDLSKMFAHLMEGKAESFHEAVEAVYLTHLLM 276

Query: 267 VKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDE 326
           +   NG + SFGR   ++  Y + D+ +GKI++++A E++ H  +    +  +R   + +
Sbjct: 277 MIESNGHSFSFGRFDQYIYPYYKADIDSGKISKEKALEIITHFFLMTNSLNKVRPWGHTQ 336

Query: 327 LFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKK 386
              G P+++   +GGM  DG       S+  L  +  +   PEPN+++ + E+ P +  K
Sbjct: 337 YSGGYPLYSNLIVGGMKPDGSEGTNDISYLCLEAM-NLSRLPEPNLSVRFCEETPRSLLK 395

Query: 387 FAAK-VSIDTSSLQYENDDLMRPDFN--------NDDYAIACCVSPMIVGK--QMQFFGA 435
            +A+ +           D+++ P             DYA   CV   I GK         
Sbjct: 396 DSARLIRKGFGMPSLFCDEVVIPAMMTLDLDIETARDYASMGCVETAIPGKWGHRATGMT 455

Query: 436 RANLAKTMLYAINGGVDEKLKMQVGPKSEPIKG--DVLNYDEVMERMDHFMDWLAKQYIT 493
             N  K +   +N G+D    +Q+   +       D  +YDE+ +  +  + + +   + 
Sbjct: 456 YINFGKILELIMNNGMDPASGIQLFSITGKNDRNIDFKSYDELWKAWETALKFYSDLAVD 515

Query: 494 ALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGL------------SVAADSLSAIK 541
              +       +  +A   A  +  + R       G             SV  DSL+A+K
Sbjct: 516 CDLVCDRSLKHFDADAFASATINCSLERGKTLKNGGAEYDYVSQSNIGPSVVGDSLAAVK 575

Query: 542 YAKVKP---IRDEDGLAIDFEIEG-----------EYPQFGNNDPRVDDLAVDLVERFMK 587
                       +   A+D   EG           + P+FGN+   VD++  D+ E ++ 
Sbjct: 576 KLVFDDKVITMKQLRDAMDTNFEGIEGAKIRKLCRQAPKFGNDIDYVDNIVADVYESYLA 635

Query: 588 KIQKLHTYRDAI------PTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRD 641
            +   HT R          T S   ITS V  G   G TPDGR AG P   GA+P  G D
Sbjct: 636 LLPNYHTDRYGCGPKGCGYTMSTSNITSYVPNGFDVGATPDGRFAGKPLNEGASPCLGAD 695

Query: 642 QKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIE 701
           ++G  A + SV+KLP      G        P AL  ++ + K      ++      A  +
Sbjct: 696 KEGPTAVINSVSKLPNKKIAGGQLLNMRFAPGALAGEENLEK--FVSFIEA-----ARYK 748

Query: 702 GGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTF 756
              H   N+++   L  A ENPE++  L +RV+GY   F++L  E Q  +I RT 
Sbjct: 749 NIFHNQFNIVDGATLKAAKENPEEHADLMVRVAGYCALFSTLMPEAQDAIIERTE 803


>UniRef50_C0QGR8 PflD1 n=1 Tax=Desulfobacterium autotrophicum HRM2
           RepID=C0QGR8_DESAH
          Length = 788

 Score =  630 bits (1624), Expect = e-179,   Method: Composition-based stats.
 Identities = 161/785 (20%), Positives = 294/785 (37%), Gaps = 87/785 (11%)

Query: 50  ATTTLW------DKVMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTE 103
               +W        + +        ++           +      Y+    E IVG +  
Sbjct: 16  RNAEVWIDPERAQIITDFYSENAGKYSIPVLRARSFKNLMEKKELYL-GDEELIVGERGR 74

Query: 104 APLKRALIPFGGIKMIEGSCKAYNRELDPMI----------KKIFTEYRKT-HNQGVFDV 152
           AP      P      I+      ++   P            KK+   +        +F+ 
Sbjct: 75  APKLIPTFPEIACHSIKDLKVLNSQNRIPYNVSPKTIKIYEKKVIPYWDGAALRDRMFNQ 134

Query: 153 YTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGI------------------DYLM 194
            + +       G++T   +    G +  D  R+   G+                  D+  
Sbjct: 135 LSDEWQTIYNCGLITETMEQRAPGSMALD-ERMFGMGLKKAKQEIEEAIKNLDFLNDFEA 193

Query: 195 KDKLAQFTSLQADLENG-VNLEQTIRLREEIAEQH---RALGQMKEMAAKYGYDISGPAT 250
            DK  Q T++    +   +  ++   + E+ + +    +   + ++MA       +    
Sbjct: 194 IDKREQLTAMAITCDGMMIYAKRYADMLEKKSSEETNKKRKKEFEKMADVCRNVPANKPR 253

Query: 251 NAQEAIQWTYFGYLAAVKSQNG-AAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHL 309
           +  E +Q ++F ++  +   NG  A + G        Y ++ L+ G++ E+ A+E++   
Sbjct: 254 DLWEVLQMSWFMHIGVITESNGWDACNPGHVDRHFFPYYKKSLETGQLDEESAKELLCAW 313

Query: 310 VMKLRMV-RFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSP 368
            +K        +             +   S+GG+  DG+  V   S+ FL  L  +    
Sbjct: 314 WIKYNNHPAPAKYGVSALESGTYNDFVNISLGGITTDGKDAVNDLSYIFLEILDEIE-FI 372

Query: 369 EPNMTILWSEKLPLNFKKFAAKVSI-DTSSLQYENDDLMRPDF--------NNDDYAIAC 419
           +P + +L S   P +F K A KV           N + +            +     I  
Sbjct: 373 QPQVHVLLSRMNPEHFLKEACKVIRKGRGFPAMFNAEAVIEQQLRVGKTISDARGGGICG 432

Query: 420 CVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMER 479
           CV     GK+        N+AK +   +  G D + K QVGPK+  +K D  +Y+E+ME 
Sbjct: 433 CVETTCYGKEAAPLIGYINIAKILELTLQNGFDTRTKKQVGPKTGNVK-DFNSYEELMEA 491

Query: 480 MDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMA------------CGI 527
                 ++    +     +  M  KY  +  L  L +  V                    
Sbjct: 492 FKKQARYIIDTKLVGSQYLIQMFAKYVPQPFLSVLIEGCVESGKDYNDGGPKYNVSILPG 551

Query: 528 AGLSVAADSLSAIKYAKVK---PIRDEDGLAIDFEIE----------GEYPQFGNNDPRV 574
            G+    DSLSAIK            E   A++ + +           + P++GN++   
Sbjct: 552 VGIGTVTDSLSAIKKHVFDESTYSMGEVIEALNADWQKSEEMRLTFANKTPRYGNDNDYA 611

Query: 575 DDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGA 634
           D +  ++ + F+  +  +   R      ++L  T ++ +G+ TG T DGRRAG P   G 
Sbjct: 612 DSIMREVSDFFIDTVDGIKDSRGGTYRMNMLPTTCHMYFGEVTGATCDGRRAGKPLSEGI 671

Query: 635 NPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYF 694
           +P+ G D  G  ASL S AK+  +    G       +P+ L  D  + K  LA L+  YF
Sbjct: 672 SPVQGADLCGPTASLKSAAKMDHSR-TCGTLLNMKFLPDVLKGDIGIHK--LASLIRTYF 728

Query: 695 HHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITR 754
            +     GG H+  NV + + L  A + PE Y  L +RV+GY+  FN++ K+ Q ++I R
Sbjct: 729 TY-----GGHHIQFNVCDAKTLQLAQKTPEDYNDLIVRVAGYSDYFNAIGKDLQDEIIQR 783

Query: 755 TFTQS 759
              ++
Sbjct: 784 YAHEA 788


>UniRef50_O32799 Formate acetyltransferase n=32 Tax=Bacilli RepID=PFL_LACLM
          Length = 787

 Score =  627 bits (1618), Expect = e-178,   Method: Composition-based stats.
 Identities = 325/781 (41%), Positives = 461/781 (59%), Gaps = 36/781 (4%)

Query: 4   LNEKLATAWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLWDKVMEGVK 63
                  AW+GF   +W+++ +V  F+Q+NY PY+GDESFLAG TE T  +   + +   
Sbjct: 6   TENIFEQAWDGFKGTNWRDKASVTRFVQENYKPYDGDESFLAGPTERTLKVKKIIEDT-- 63

Query: 64  LENRTHAPVDFDTAVASTITSHDAGYIN---KQLEKIVGLQTEAPLKRALIPFGGIKMIE 120
             +       FDT   ++I    AGYI+   K+LE I G+Q     +   +P GG+++ E
Sbjct: 64  KNHYEEVGFPFDTDRVTSIDKIPAGYIDANDKELELIYGMQNSELFRLNFMPRGGLRVAE 123

Query: 121 GSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIG 180
                +   +DP +  + ++   + N G+F  YT  I + R +  +TGLPDAY RGRIIG
Sbjct: 124 KILTEHGLSVDPGLHDVLSQTMTSVNDGIFRAYTSAIRKARHAHTVTGLPDAYSRGRIIG 183

Query: 181 DYRRVALYGIDYLMKDKLAQFTSLQADLENGVNLEQTIRLREEIAEQHRALGQMKEMAAK 240
            Y R+ALYG DYLMK+K  ++ ++          +  IRL+EEI  Q++AL ++    A 
Sbjct: 184 VYARLALYGADYLMKEKAKEWDAITE------INDDNIRLKEEINMQYQALQEVVNFGAL 237

Query: 241 YGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQ 300
           YG D+S PA N +EAIQW    Y+A  +  NGAA S GR    LD++ ERDL  G  TEQ
Sbjct: 238 YGLDVSRPAMNVKEAIQWVNIAYMAVCRVINGAATSLGRVPIVLDIFAERDLARGTFTEQ 297

Query: 301 EAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNT 360
           E QE VD  ++KLR ++F R   YDEL+SGDP + T S+ GMG DGR  VTK  +RFLNT
Sbjct: 298 EIQEFVDDFILKLRTMKFARAAAYDELYSGDPTFITTSMAGMGNDGRHRVTKMDYRFLNT 357

Query: 361 LYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNNDDYAIACC 420
           L T+G +PEPN+T+LW  KLP +FK+++  +S   SS+QYE  + M  D   +   I+CC
Sbjct: 358 LDTIGNAPEPNLTVLWDSKLPYSFKRYSMSMSHKHSSIQYEGVETMAKDGYGEMSCISCC 417

Query: 421 VSPMIVGKQMQ-----FFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDE 475
           VSP+    +       +FGAR N+ K ML  +NGG D+  K       EP++ ++L+YD 
Sbjct: 418 VSPLDPENEEGRHNLQYFGARVNVLKAMLTGLNGGYDDVHKDYKVFDIEPVRDEILDYDT 477

Query: 476 VMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVAAD 535
           VME  D  ++WL   Y+ A+NIIHYM DKY+YEA  MA     V   M  GI G +   D
Sbjct: 478 VMENFDKSLNWLTDTYVDAMNIIHYMTDKYNYEAVQMAFLPTKVRANMGFGICGFANTVD 537

Query: 536 SLSAIKYAKVKPIRDEDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTY 595
           SLSAIKYAKVK +RDE+G   D+E+EG++P++G +D R DD+A  +++ + +K+     Y
Sbjct: 538 SLSAIKYAKVKTLRDENGYIYDYEVEGDFPRYGEDDDRADDIAKLVMKMYHEKLASHKLY 597

Query: 596 RDAIPTQSVLTITSNVVYGKKTGNTP---------DGRRAG---APFGPGANPMHGRDQK 643
           ++A  T S+LTITSNV Y K+TGN+P         DG         F PGANP + + + 
Sbjct: 598 KNAEATVSLLTITSNVAYSKQTGNSPVHKGVFLNEDGTVNKSKLEFFSPGANPSN-KAKG 656

Query: 644 GAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEG- 702
           G + +L S+AKL F  A DGIS T  + P ALGK  + +  NL  ++DGYF   A I G 
Sbjct: 657 GWLQNLRSLAKLEFKDANDGISLTTQVSPRALGKTRDEQVDNLVQILDGYFTPGALINGT 716

Query: 703 ---GQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQS 759
              GQH+N+NVM+ + + D +   E    + +R+SGY V    LT EQ+Q++  R F + 
Sbjct: 717 EFAGQHVNLNVMDLKDVYDKIMRGE---DVIVRISGYCVNTKYLTPEQKQELTERVFHEV 773

Query: 760 M 760
           +
Sbjct: 774 L 774


>UniRef50_C7N778 Pyruvate-formate lyase n=1 Tax=Slackia heliotrinireducens DSM 20476
           RepID=C7N778_SLAHD
          Length = 789

 Score =  625 bits (1611), Expect = e-177,   Method: Composition-based stats.
 Identities = 148/771 (19%), Positives = 282/771 (36%), Gaps = 81/771 (10%)

Query: 59  MEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFG--GI 116
            E  +       P+ F   V + I       +    E IVG  T A     L P      
Sbjct: 29  TEAYQKFAGDAVPI-FRAKVVNYILERMTTLVL-DDELIVGTATNAYRGANLHPEFQSSS 86

Query: 117 KMIEGSCKAYNRELDPMIK---------KIFTEYRKTHNQGVFDVYTPD-ILRCRKSGVL 166
             I    +   R  DP                 +     + V +   P  I       +L
Sbjct: 87  WYISDIDEFQTRTKDPYYISAEDRETILATLPYWEGKAMEDVAEEAMPAYIKELESDDIL 146

Query: 167 TGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLEN-----------GVNLE 215
               +    G    D+ ++   GI   + +      ++                  +  E
Sbjct: 147 CVGLENGVSGETTCDHEKIMAVGIRGYIDECQRNIDAIVPQTMEDQAKVDFWKACIIQSE 206

Query: 216 QTIRLREEIAEQHRALG----------QMKEMAAKYGYDISGPATNAQEAIQWTYFGYLA 265
             I     +A++   L           ++++MA         P     +A Q  +F ++A
Sbjct: 207 GLITYAHRMADEADRLADACDDPVRAAELRQMAENCRVVPENPPQTFWQACQMVWFIHVA 266

Query: 266 AVKSQNGAAMSFGRTSTFLDVYIERD-LKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEY 324
                   A+ FGR   ++  + ++D +    IT  +A E+++ L +K   V  +R   Y
Sbjct: 267 FYIEVCTTAIGFGRFDQYMWPFYKKDVIDEKNITRDQALEILESLYLKSCEVYEVRDSWY 326

Query: 325 DELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNF 384
              F+G P+W    +GG   DG+      S   L     +  + +P M +   +  P   
Sbjct: 327 ATSFAGYPMWQILVVGGQTRDGKDASNDLSMLCLEAADAL-QTTQPVMALRVCDTTPEEL 385

Query: 385 KKFAAKVSI-DTSSLQYENDDLMRPD--------FNNDDYAIACCVSPMIVGKQMQFF-- 433
            +F  K++    ++  + ND               +  D+ I  C+     G        
Sbjct: 386 IRFGCKMTQEGQANPGFFNDATAMKMALAKGGTLEDARDWTIVGCIQAGPGGGGTDGSPD 445

Query: 434 GARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYIT 493
               N+ K + + ++ GVD      +G ++   + +  N ++  + +   +     Q   
Sbjct: 446 AGYVNMGKMIEFVLHDGVDPATGKLMGLRTGDPR-EFKNIEQFKDALKKQIVHAYDQIRI 504

Query: 494 ALNIIHYMHDKYSYEASLMALHDRDVIRTMACG------------IAGLSVAADSLSAIK 541
             N++  +H           +    V    +              + G +  ADS++A++
Sbjct: 505 GYNLMQSIHMNRYPVIFASMVTRGCVENGKSVQHGGANVSTAGMYVTGAANLADSIAAVE 564

Query: 542 YAKVKP---IRDEDGLAIDFEIEG----------EYPQFGNNDPRVDDLAVDLVERFMKK 588
               +      +E   A D   EG          + P++GN+DP VD +  +++    + 
Sbjct: 565 KCVFEDHDLTMEELIRACDTNFEGQERLRQMLLNKPPKYGNDDPHVDAIYREMMHHIAET 624

Query: 589 IQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVAS 648
           +Q+    R       + + T N+ +G+ TG  PDGR AG      ++PM GRD  G  ++
Sbjct: 625 VQQWPDARGGHYAFGIDSQTMNLPHGQVTGALPDGRLAGESLCDASSPMMGRDICGPTST 684

Query: 649 LTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNV 708
           + SVA +     ++G  +     P  +  +       + G++  +F +     GG+H+ +
Sbjct: 685 VKSVAAIDQDILQEGALFNLRFDPKGVQGEKG--IDIIEGVVKTFFQN-----GGEHIQI 737

Query: 709 NVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQS 759
           NV++ + L+DA ++PE +  L +RV+GY   F  L K+ Q  +I RT   S
Sbjct: 738 NVVDNDTLIDAQKHPELHRGLMVRVAGYMAYFTELDKQAQDTIIRRTPHLS 788


>UniRef50_B8FFL2 Formate C-acetyltransferase n=1 Tax=Desulfatibacillum alkenivorans
           AK-01 RepID=B8FFL2_DESAA
          Length = 803

 Score =  623 bits (1607), Expect = e-177,   Method: Composition-based stats.
 Identities = 161/781 (20%), Positives = 290/781 (37%), Gaps = 96/781 (12%)

Query: 43  FLAGATEATTTLWDKVMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQT 102
           +       +  ++ ++ E +    +             +I  H         E IVG  T
Sbjct: 51  YFKDKANQSKHVYVQMAEALAHSQKNR-----------SIAVHPG-------ELIVGNYT 92

Query: 103 EAPLKRALIPF-GGIKMIEGSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRCR 161
              +   L P   G+ +++   K  NRE +P+      + R      +   +   +L  +
Sbjct: 93  SRRVGGLLFPELHGLVVMQDLFKFPNRETNPLEVSRLDQARLL---SIAPFWATRMLAVK 149

Query: 162 K---------------SGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQA 206
                            G    + +A G   I  DY  +   G D +             
Sbjct: 150 TCDSWLDTFSLVLNQLMGNYYIINEAAGISHIAPDYETLCRLGTDGIAAKAAKLQKQSLM 209

Query: 207 DLENGVNLE--------------QTIRLREEIAEQHRA---LGQMKEMAAKYGYDISGPA 249
           D +     E              +  +L  E+AE+        ++K +A          A
Sbjct: 210 DADKWYFYESVRIAAEGLAAFGERYAQLAGEMAERELDEDLAAELKGIAEVCSRVPRKGA 269

Query: 250 TNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHL 309
              +EA+Q  +F  +A        ++  GR   +L  Y E+DLKAG +T +EA+E+    
Sbjct: 270 KTFREALQSCFFAQIAINNESLDNSVCPGRMDHYLYPYYEKDLKAGLLTREEAKELAGAF 329

Query: 310 VMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPE 369
            +K+  +  + +        G       ++GG   +G+    + +  FL  +  +    +
Sbjct: 330 SVKMSEIVPVFSKYITRTHGGFFNGQIVNVGGTHKNGKDSTNELTMIFLEVMDEL-RMRQ 388

Query: 370 PNMTILWSEKLPLNFKKFAAKVS-IDTSSLQYENDDLMRPDF--------NNDDYAIACC 420
           PN T    +  P  +      +     +S    ND+++ P          +  +Y    C
Sbjct: 389 PNYTARVHKNSPKEYLDKVYGILSKGANSPSIYNDEVIVPVLKQNGVKIGDARNYTPVGC 448

Query: 421 VSPMIVGKQMQFFG-ARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMER 479
           V P+  G        A  N A  +  A+N G       Q+G K++P+   +   ++V E 
Sbjct: 449 VEPVAQGVSFSSTDAALFNTAIILELALNQGRRLGRVAQIGAKTKPV-SQMTCIEDVQEA 507

Query: 480 MDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRT------------MACGI 527
            +  M     + +  L  I   + +Y        L D  +                    
Sbjct: 508 FEIQMFHGINRLLKDLQAIEIANAEYHPTPLSSMLLDGCLENGACSTRGGARYNFSGIQC 567

Query: 528 AGLSVAADSLSAIK---YAKVKPIRDEDGLAIDFEIEG--------EYPQFGNNDPRVDD 576
            GL  A DSL+AIK   +   K   +E    +   +            P+FGN+DP  D 
Sbjct: 568 VGLVDAGDSLAAIKQAVFEDKKLSMEELVEHLKNNLSDDRWRHYLLNMPKFGNDDPFADV 627

Query: 577 LAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANP 636
                ++ F   +    + R    T  V ++T +  +G      P+GRR G     G +P
Sbjct: 628 WTAYALDVFKAALDGKTSTRGGKYTVGVYSVTLHEYWGTVVSALPNGRRNGESLSNGMSP 687

Query: 637 MHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHH 696
            +G+D+KG  A L S+ ++ ++   +GI++      N +G       T +  +   YF  
Sbjct: 688 SNGQDRKGPTAVLNSMNRIDYSKTDNGINFNIKFDANTVGSPAGC--TAMKSIFSTYFK- 744

Query: 697 EASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTF 756
                GG    +NV++ ++L++A +NPE YP L +RVSGY+  FN LT   ++++I RT 
Sbjct: 745 ----RGGMQAQINVLDPKVLIEARDNPEAYPHLLVRVSGYSAYFNDLTPAMKEEMIRRTS 800

Query: 757 T 757
            
Sbjct: 801 M 801


>UniRef50_A5N4Z6 Predicted glycyl radical enzyme n=2 Tax=Clostridium kluyveri
           RepID=A5N4Z6_CLOK5
          Length = 800

 Score =  616 bits (1588), Expect = e-174,   Method: Composition-based stats.
 Identities = 162/778 (20%), Positives = 295/778 (37%), Gaps = 92/778 (11%)

Query: 56  DKVMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGG 115
             + E  K+     +           I  +   YI K    I+G +   P      P   
Sbjct: 38  VLLTEAYKMYEGKFSIPVLRGLAFKYIMENRTLYIEK-GAIIIGEKGHKPWAAPTFPELC 96

Query: 116 IKMIEGSCKAYNRE-----------------LDPMIKK----------IFTEYRKTHNQG 148
              ++      NRE                 + P  K           +  E+ K  + G
Sbjct: 97  CHTLKDFDNMNNREKVFFKVSEEDKRIQKEVIIPYWKDRALMTRMNKLLPDEWHKLFDAG 156

Query: 149 VFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKD-------KLAQF 201
           ++     + L  R  G        Y +G I  D+     Y ID+L  +       K  + 
Sbjct: 157 LY----TEFLMQRGPGHTVADGKIYRKGYI--DFINDIQYEIDHLDYNNDVLALNKKEEL 210

Query: 202 TSLQADLENGVNL-EQTIRLREEIAE---QHRALGQMKEMAAKYGYDISGPATNAQEAIQ 257
             ++   E  +   E+       +A      +   ++ E+A              ++A+Q
Sbjct: 211 EGMKLVCEGMIIFGERYADQARALASVENDPQWKEELLELAEVCDVVPKHAPRTFRQAVQ 270

Query: 258 WTYFGYLAAVKSQNG-AAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRM- 315
             +F ++      N   A S G+    L+ + E+D++ G++T +EA E++++L ++    
Sbjct: 271 MYWFTHIGVTTEMNNWDAYSPGKLDQHLEPFYEKDIEEGRLTREEALEILENLWIQFNNQ 330

Query: 316 VRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTIL 375
               +     +  +    +   + G +  DG T V++ S+  L  +  M    +P+  + 
Sbjct: 331 PTPPKVGITLKESATYTDFCNINTGALRPDGTTGVSEVSYLILEVMDEM-KLLQPSSNVQ 389

Query: 376 WSEKLPLNFKKFAAKVSI-DTSSLQYENDDLMRPDF--------NNDDYAIA-CCVSPMI 425
            S K P  F + A K+S        + N + +  +         +  +  IA  CV    
Sbjct: 390 ISRKTPEKFLREALKISRKGWGQPAFYNSEAIIQELLFLGKSIDDARESGIASGCVETGT 449

Query: 426 VGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMD 485
            GK+        N+ K     +N G D   K QVG      +    +Y EV +     ++
Sbjct: 450 AGKEAYVLTGYLNIPKIFELVLNRGFDSYTKKQVGLDLGDPR-KFKSYQEVYDAFYKQLE 508

Query: 486 WLAKQYITALNIIHYMHDKYSYEASLMALHDRDV------------IRTMACGIAGLSVA 533
           ++    I   N+I  M+ +Y     L  + D  +              T      G++  
Sbjct: 509 YVVNVKIAGNNLIERMYMEYMPVPLLSVITDDCIKSGVDYNAGGARYNTSYIQCVGIATI 568

Query: 534 ADSLSAIK---YAKVKPIRDEDGLAIDFEIEG----------EYPQFGNNDPRVDDLAVD 580
            DSL +IK   +   K   DE   A   + +G            P++GN+D   DD+  D
Sbjct: 569 TDSLVSIKKNVFEDKKFSMDELLKACKADFKGYDEIFETVYNHTPKYGNDDDYADDILRD 628

Query: 581 LVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGR 640
           + +     I    T + +      L  T +V +G+    +P+GR AG P   G +P  G 
Sbjct: 629 VSQSLQDAIAGRTTPKGSTTVVEFLPTTCHVYFGQVMEASPNGRHAGIPLPGGISPEKGA 688

Query: 641 DQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASI 700
           D+ G  + + S +K+       G        P+ +  ++    +N+A L+  YF  +   
Sbjct: 689 DRNGPTSVVKSASKIDQLK-TGGALLNQKFTPSVVQGEEG--ISNMATLVRSYFSMD--- 742

Query: 701 EGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQ 758
             G H+  NV++R+ LLDA ++PE+Y  L +RV+GY+  FN+L +  Q ++I RT   
Sbjct: 743 --GHHIQFNVIDRKTLLDAQKHPEEYENLIVRVAGYSDYFNNLDRALQDEIINRTEQS 798


>UniRef50_A8MJE8 Formate C-acetyltransferase n=57 Tax=Bacteria RepID=A8MJE8_ALKOO
          Length = 849

 Score =  613 bits (1580), Expect = e-173,   Method: Composition-based stats.
 Identities = 147/752 (19%), Positives = 280/752 (37%), Gaps = 94/752 (12%)

Query: 87  AGYINKQLEKIVGLQTEAPLKRALIPFGGIKMIE-GSCKAYNRELDPMI----------K 135
           A  + ++ E IVG     P   A  P    + +E       NR  DP            +
Sbjct: 114 APLLIQEDELIVGAPCGQPRAGAFSPDIAWRWMEDEIDTIGNRPQDPFYISEEDKRYMRE 173

Query: 136 KIFTEYRKTHNQ----------GVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRV 185
           ++F  ++               GV+++     +       L G  D+         Y  +
Sbjct: 174 ELFPFWKGKSVDEYCEDQYRDAGVWEISGESFVSDCSYHALNGGGDSN------PGYDVI 227

Query: 186 A-LYGIDYLMKDKLAQFTSLQ----ADLENGVNLEQTIR-------LREEI--------- 224
               G+  + K+       L      D+E     +  I            +         
Sbjct: 228 LMKKGMIDIQKEAQEHLEKLSYDNPDDIEKIYYYKAVIETTEGVMIYARRLADHAADLAA 287

Query: 225 -AEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTF 283
                +   +++ ++       +   +   EAIQ  +      V  +N   MS GR   +
Sbjct: 288 KETNPKRKAELQRISEINRRVPANKPSTFWEAIQAVWTIESLLVVEENQTGMSIGRVDQY 347

Query: 284 LDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMG 343
           +  + + D+++G++TE EA E+   +++K+  + ++ +    + F+G   +    +GG+ 
Sbjct: 348 MYPFYKADIESGRMTEFEAFELAGAMLIKMSEMMWVTSEGGSKFFAGYQPFVNMCVGGVT 407

Query: 344 LDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSI-DTSSLQYEN 402
            +G       ++  ++ +  +    +P++      K P  + K    V            
Sbjct: 408 REGLDATNDLTYLLMDAVRHV-KIYQPSLATRIHSKSPKKYLKKIVDVVRSGMGFPACHF 466

Query: 403 DDLMRPDF--------NNDDYAIACCVSPMIVGKQMQFFG-ARANLAKTMLYAINGGVDE 453
           DD+             +  DY +  CV P   G+  Q+   A       +   +N GV  
Sbjct: 467 DDVHIKMMLAKGVSIEDARDYCLMGCVEPQKSGRLYQWTSTAYTQWPIAIELVLNNGVPL 526

Query: 454 KLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMA 513
               QV P    I      Y++    +   + ++ K    A  I   +H   + +  +  
Sbjct: 527 WYGKQVTPNMGDIN-QYKTYEQFEAAVKEQIQYITKLSNIATVISQRVHRDLAPKPLMSI 585

Query: 514 LHDRDVIRTMACGIA-------------GLSVAADSLSAIK---YAKVKPIRDEDGLAID 557
           +++  +                      GL+   DS++AIK   +   K    +   A+ 
Sbjct: 586 MYEGCMESGKDVSAGGAMYNFGPGVVWSGLATYVDSMAAIKKLVFDDKKYTLQQLNEALK 645

Query: 558 FEIEG---------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTIT 608
            +  G         + P++GN+D  VD +A DLV    K+ +K  T   +I     L+I+
Sbjct: 646 ADFVGYDQVKSDCLKAPKYGNDDDYVDLIAADLVNFTEKEHRKYRT-LHSIMCHGTLSIS 704

Query: 609 SNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTF 668
           +N  +G+ TG T +GR A  P   G +P  G D KG  A + SV+K+       G+ + F
Sbjct: 705 NNTPFGQLTGATANGRGAWTPLSDGISPTQGADFKGPTAIIKSVSKMACDNMNLGMVHNF 764

Query: 669 SIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQ 728
            ++   L   +      +  L+       A+  G   +  N ++   LL+A ++PEKY  
Sbjct: 765 KLIAGLLDTPEGEE--GIITLLRT-----ANNIGIGEMQFNYLDNNTLLEAQKHPEKYRD 817

Query: 729 LTIRVSGYAVRFNSLTKEQQQDVITRTFTQSM 760
           L +RV+GY+  F  L K+ Q ++I+RT     
Sbjct: 818 LIVRVAGYSAFFVELCKDVQDEIISRTMLTHF 849


>UniRef50_C0W9F6 Formate C-acetyltransferase n=1 Tax=Acidaminococcus sp. D21
           RepID=C0W9F6_9FIRM
          Length = 805

 Score =  611 bits (1575), Expect = e-173,   Method: Composition-based stats.
 Identities = 163/769 (21%), Positives = 291/769 (37%), Gaps = 83/769 (10%)

Query: 59  MEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIKM 118
            EG K        +       + + +    YI +  E +VG     P    L P     +
Sbjct: 40  TEGFKEMEGQPWIIQRANGYYN-VCAKKNIYI-QPHELLVGGVGFKPRCGILNPDSASGV 97

Query: 119 I-EGSCKAYNRELDPMI-----KKIFTEYRKTH--NQGVFDVY----TPDILRCRKSG-V 165
           I +       R  DP       KK++TE  + +  N+ VFD +      D  R R +G +
Sbjct: 98  IAKELDTISTRPFDPFYLSEEGKKVYTEKVQNYWKNKCVFDRWNLMLPEDAKRLRANGAI 157

Query: 166 LTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQA----DLENGVNLE------ 215
                   G G     + R+   G+  + K+       L      DLE     +      
Sbjct: 158 FIDRKAVRGYGENTPGWMRILTKGLAAIRKEAEDALAKLDDANPGDLEKSFFYKAEIKAA 217

Query: 216 --------QTIRLREEIA---EQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYL 264
                   +   L E++A   +      ++ ++A    +    PA    EA Q       
Sbjct: 218 DAVILLAHRHADLAEKMAAECDDPVRKAELLKIAEVTRHVPEYPARTFYEACQSIISYEY 277

Query: 265 AAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEY 324
           A    QN ++ + GR   +L  Y ++D +AG +T+ +AQE++D L +K+  +   +    
Sbjct: 278 ACFMEQNASSYNLGRLDQYLYPYYKKDKEAGILTDDDAQELLDCLWIKVAEMSLFQDEVT 337

Query: 325 DELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWS-EKLPLN 383
            +  +G  I    S GG+   G     + S+  +     +    EPNM + +S  K P +
Sbjct: 338 AQYAAGYCITVQTSCGGIDQYGNDASNELSYMMIQATEDV-RFKEPNMAMTYSISKNPDS 396

Query: 384 FKKFAAK-VSIDTSSLQYENDDLMRPDF--------NNDDYAIACCVSPMIVGKQMQFFG 434
             + A + + +  +     ++D+                ++    CV   + GK  Q+  
Sbjct: 397 LLRKAIESIGMGLTMPAIYSNDVGIQMLQNKGIPLREAWNWNPCGCVETNLSGKMKQYTD 456

Query: 435 -ARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYIT 493
            A  N+   + +A+N G       QV   +   +     +D+    +   +D+     ++
Sbjct: 457 IADINMGAMVEFALNDGKSRITGEQVSIHTGDPRN-FKTFDDFFAAVKKHIDYAVDVIVS 515

Query: 494 ALNIIHYMHDKYSYEASLMALHDRDVIRTM--------------ACGIAGLSVAADSLSA 539
              ++ Y+   Y    +L   ++  +                       G +   +S++ 
Sbjct: 516 CNQLLDYLSMNYRPVPTLSLSYEHCMEVGKDYSQPGGAQYNAGGGVITVGQADIINSIAD 575

Query: 540 IKYAKV---KPIRDEDGLAIDFEIEG---------EYPQFGNNDPRVDDLAVDLVERFMK 587
           +KY      K   D    A+D   EG         E P++GN+DPR D    ++      
Sbjct: 576 VKYLVFDEKKISMDTLIKALDANFEGYEDIQKLCLEAPKYGNDDPRADFCVGEIFNHVAD 635

Query: 588 KIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVA 647
           + +K  T    + T  +L ++ N   G+  G  P GR+A  P   G     G D  G  A
Sbjct: 636 QFEKYDTVFGKM-TLGMLPVSGNTPIGQWVGALPSGRKATTPLTDGIGATGGTDVNGPTA 694

Query: 648 SLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLN 707
            L SV+ LP A    G        P+ +  ++ +  T+   ++        S+ G  H  
Sbjct: 695 LLKSVSHLPHARFTQGTQLNMKFEPDLIKGENGM--THAMNMVKT-----MSVLGVYHAQ 747

Query: 708 VNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTF 756
           +N ++RE L+DA ++P  +  L IRV+GY   F  L KE Q ++I RT 
Sbjct: 748 INCVDRETLIDAQKHPNDHRDLLIRVAGYTAFFVELGKETQDEIIGRTE 796


>UniRef50_B8FA81 Formate C-acetyltransferase n=1 Tax=Desulfatibacillum alkenivorans
           AK-01 RepID=B8FA81_DESAA
          Length = 831

 Score =  603 bits (1555), Expect = e-171,   Method: Composition-based stats.
 Identities = 159/763 (20%), Positives = 296/763 (38%), Gaps = 84/763 (11%)

Query: 59  MEGVKLENRTHAPVDFDTA----VASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFG 114
           ME   L NR+  P   D      +   I  +  G   +  +K++  +     K A+ P  
Sbjct: 92  MELDFLLNRSRQPFSIDPDDRRELEEDILPYWRGRTVRDRKKVLWKENGLNFKPAVDP-- 149

Query: 115 GIKMIEGSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYG 174
                      Y R     ++KI    +       +      +     +     +     
Sbjct: 150 --------LSLYKRHKSLDLQKIKKAAKVPGGDAAYA--LKGMKEILHNNPALVMNVFDV 199

Query: 175 RGRIIGDYRRVALYGIDYLMKDKLAQFTS----------------LQADLENGVNLEQTI 218
           +G +I   + V   G   +M                         + +     +  E+  
Sbjct: 200 QGHLILGIKNVLSQGFSGIMAQAEKGLAEAKEAGKADDAAFYESVMISCEAAKILAERLA 259

Query: 219 RLREEIAEQHRALG---QMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAM 275
           +  EE A +        ++   A +  +    P     EA+Q  +   L  + S     +
Sbjct: 260 KKAEEAASEENDPDRQRELLAAAKRCRHSPWNPPRTFHEAVQAMWLILLGGLVSHGMVGI 319

Query: 276 -SFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIW 334
            + GR   +L  Y ++D+++G+I +  A  +++ L++KL     +    Y    +G+ + 
Sbjct: 320 LAVGRLDQYLYPYYKKDVESGRIDQAMAVRLMEELLIKLGANLMILP--YVGKNTGNELG 377

Query: 335 ---ATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKV 391
                 +IGG+   G+  V   ++  L     +      + T+  S++ P  F + A + 
Sbjct: 378 SDSCVPTIGGVDAQGKDAVNPLTYAVLEAFANVKSLGN-SFTVRLSQESPPEFWQKALET 436

Query: 392 SIDTSSLQYENDDLMRPDF--------NNDDYAIACCVSPMIVGKQMQFFGAR-ANLAKT 442
             +TS     ND+++ P          +  DY +  CV P   G           +L+  
Sbjct: 437 YRETSGAALFNDEIVTPALQNCGMTLEDARDYGVIGCVEPTGDGDAFGCTSGNDVSLSAA 496

Query: 443 MLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMH 502
           +  A+  G    +   +GPK+   K     +D+V+E     ++++      A+N+   ++
Sbjct: 497 LEMALGDGYLRVMGKAIGPKTGNPK-KFKTFDQVLEAFKKQVEFMVDTVARAVNLKDQIY 555

Query: 503 DKYSYEASLMALHDRDV--IRTMACGIA----------GLSVAADSLSAIK---YAKVKP 547
            +  +   +       +   R M  G A          G+  AADSL+AIK   + +   
Sbjct: 556 MEEYHNPYISCTLTGCLDNARDMTQGGAKYNFGSISGRGMGTAADSLAAIKCFVFDQKTF 615

Query: 548 IRDEDGLAIDFEIEG----------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRD 597
              +    +D   +G            P FG++DP  DD+A ++   F K +    T R 
Sbjct: 616 SMAKILKMLDCNFKGYDKERAMLAHRAPAFGSDDPYADDIAKEVCAFFCKTVASKQTLRG 675

Query: 598 AIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPF 657
                S  +   +V+ G   G TP+GR AG P     +P +G +++G    L SVAKL  
Sbjct: 676 GPFRPSFFSYGVHVLEGLYIGATPNGRLAGTPVSNSLSPTNGSEKQGPTGVLGSVAKLDH 735

Query: 658 AYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLL 717
           +   +G S    ++P+    ++ + K  + GL+ G+F       GG  +  NV++ + LL
Sbjct: 736 SLISNGSSVNIKLMPSMFQGEERLNK--MIGLVKGFF-----ASGGMEVQPNVVSNQTLL 788

Query: 718 DAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQSM 760
           DA ++PE Y  L +RVSGY+  F  L K  Q ++I RT  + +
Sbjct: 789 DAQKHPENYRDLVVRVSGYSAFFTDLGKPIQDEIIQRTEFEGL 831


>UniRef50_C0C5J5 Putative uncharacterized protein n=1 Tax=Clostridium hylemonae DSM
           15053 RepID=C0C5J5_9CLOT
          Length = 797

 Score =  603 bits (1554), Expect = e-170,   Method: Composition-based stats.
 Identities = 155/740 (20%), Positives = 286/740 (38%), Gaps = 85/740 (11%)

Query: 93  QLEKIVGLQTEAPLKRALIPFGGIKMI-EGSCKAYNRELDPMIKKIFTEYRKTHNQGVFD 151
           + E IVG          L       ++ +       R+ DP    +  E ++     +  
Sbjct: 64  EKELIVGCAGSKMRGGILSADTCWSILDKELETINERQYDPFY--LRPEDKQMFLDVIKP 121

Query: 152 VY-------------TPDILRCRKSGVLTGLPD-AYGRGRIIGDYRRVALYGIDYLMKDK 197
            +               D    R +G +        G G     Y ++   GI+ +M   
Sbjct: 122 FWEGRSTYEAWLKQIPEDCRNLRDTGQVYIDKKAVRGWGETTVGYTQIINEGIESIMDTV 181

Query: 198 LAQFTSLQADLENGVN------------------LEQTIRLREEIAEQHRALG---QMKE 236
            A+  +L       ++                   ++     + +A +        ++  
Sbjct: 182 KAEREALDLTEPGAIDKDNYLQALLISAEGICMMAKRYADEADRLAAEEEDAERRSELLT 241

Query: 237 MAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGK 296
           +A         PA + QEA+Q  YF +++    QN AA + GR   +L  Y + DL+ G 
Sbjct: 242 IARTCRRVPRYPARSFQEALQSFYFYHISIFMEQNAAAYNPGRMDQYLYPYYKSDLEEGT 301

Query: 297 ITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFR 356
           ITE+E  E+++ L +K       +        +G P++ T   GG+  +G   V   S+ 
Sbjct: 302 ITEEEGLELLECLWVKFAEPCVFQDATTARYSAGYPMFQTLCCGGIDSEGNDAVNDVSYM 361

Query: 357 FLNTLYTMGPSPEPNMTILWS-EKLPLNFKKFAAK-VSIDTSSLQYENDDLMRPDFNND- 413
            L     +    +PN+T+ +S  K P  F K  A+ +S+ T    + NDD+      N  
Sbjct: 362 MLQATEDV-QLYQPNLTVRYSMAKNPNRFLKKIAQVISLGTGFPAFHNDDVGIRMLMNKG 420

Query: 414 -------DYAIACCVSPMIVGKQMQFFG-ARANLAKTMLYAINGGVDEKLKMQVGPKSEP 465
                  D+  A CV   + G+   +   A  NL   + +A+  GV+ K   +V  ++  
Sbjct: 421 IPLKEAFDWNPAGCVETNLEGRLRHYSAFADINLGGMIEFAMTNGVNRKSGRKVSAETGD 480

Query: 466 IKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIR---- 521
                  Y +    +   + +  +  +   ++I  +        +L       V +    
Sbjct: 481 PAS-FTEYGDFEHAVKEQLKFSIQACVKGSHVIDDICMDRV-VPALSLSFRECVEQAKDY 538

Query: 522 ---------TMACGIAGLSVAADSLSAIK---YAKVKPIRDEDGLAIDFEIEG------- 562
                         + G++   +S+ A+K   Y K     ++   A++ + EG       
Sbjct: 539 AWGGAKYNAGNGIILIGVADLINSMEAVKELVYEKKLVSMEDMVNALNADFEGYEEIREL 598

Query: 563 --EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNT 620
             +  ++GN+D  V+++A  ++     +I++ H+      T  +L ++ N  +G+  G  
Sbjct: 599 CQKCRKYGNDDEEVNEIASHMLTFIADEIEQYHSKFG-QMTPGILPVSGNTPFGQDVGAL 657

Query: 621 PDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDE 680
           P GR+A  P   G +P  G D  G  A L S A +P A    G      + P+ +  ++ 
Sbjct: 658 PSGRKAWTPLADGISPNGGTDVSGPAAVLKSAASIPHARYVQGTLLNMKLEPDMVKTENG 717

Query: 681 VRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRF 740
           ++   L  L+           G  H+  NV++RE LL A + PE Y  L +RV+GY   F
Sbjct: 718 IQ--QLMALLKSLCTL-----GVYHVQFNVIDRETLLAAQKKPEDYRGLLVRVAGYTAYF 770

Query: 741 NSLTKEQQQDVITRTFTQSM 760
             L K+ Q ++I+RT   S 
Sbjct: 771 TELGKDVQDEIISRTAQSSF 790


>UniRef50_Q312S2 Formate C-acetyltransferase n=9 Tax=Bacteria RepID=Q312S2_DESDG
          Length = 829

 Score =  598 bits (1541), Expect = e-169,   Method: Composition-based stats.
 Identities = 147/789 (18%), Positives = 279/789 (35%), Gaps = 96/789 (12%)

Query: 56  DKVMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGG 115
               + +K        + +       +  H   YI+   + I G          L P   
Sbjct: 53  KLFTDSMKETEGQPLVLRW-AKAMKHVAEHITVYID-DDQLICGRGGCPGRYGVLYPELD 110

Query: 116 IKMIE-GSCKAYNRELDPM----------IKKIFTEYR-KTHNQGVFDVYTPDILRCRKS 163
              ++       NR   P           +++I   ++ KT+++ +      D+ +    
Sbjct: 111 GDFLDLAIEDLPNRTESPFTITEADARVVVEEIAPYWKGKTYHEDLNLALPSDVHKLTYD 170

Query: 164 G--------VLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQA-----DLEN 210
                    ++          + + DY +V   G   L ++   +   L       ++E 
Sbjct: 171 DPQGLKSRFIVNETSSFRSSIQWVHDYEKVLKRGFRGLKEEAQEKIAGLDPLSPRDNVEK 230

Query: 211 GVNLEQTIRLREEI-----------------AEQHRALGQMKEMAAKYGYDISGPATNAQ 253
              LE  + + + I                         +++ MA    +    PA N  
Sbjct: 231 RPFLEAIVIVCDAIILWANRHAKLAADMAAAETNPVRKAELETMAEICAWVPENPARNFY 290

Query: 254 EAIQWTYFGYLAAVKSQ-NGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMK 312
           EA+Q  +F  + +   Q  G  +S GR   +   +  +D++ G+ITE+ A E+++ + + 
Sbjct: 291 EAVQAQWFTQMFSRLEQKTGTIVSNGRMDQYFWPFYRKDIEEGRITEESALELLECMWVG 350

Query: 313 LRM-VRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPN 371
           +   V    +P       G   W   +IGG    G       ++ FL +     P   P+
Sbjct: 351 MAQYVDLYISPAGGAFNEGYAHWEAVTIGGQTPQGLDATNDLTYLFLKSKREF-PLHYPD 409

Query: 372 MTILWSEKLPLNFKKFAAK-VSIDTSSLQYENDDLMRPDF--------NNDDYAIACCVS 422
           +      + P  +    A+ +   +   +  ND+ + P +           DYA++ C  
Sbjct: 410 LAARIHSRSPERYLHDVAETIKFGSGFPKLINDEEIVPLYVSKGASFEEALDYAVSGCTE 469

Query: 423 PMIVGKQMQFFG-ARANLAKTMLYAINGGVDEKLKM-QVGPKSEPIKGDVLNYDEVMERM 480
             +  +     G A  N A  +   +  G   K    ++G ++         ++E     
Sbjct: 470 ARMPNRDTYTSGGAYINFAAALEMVLYNGRMLKYGENELGLETGDPTR-FETWEEFWNAY 528

Query: 481 DHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGI------------- 527
               +   +      +II+ +  ++  +    ALHD  +   +                 
Sbjct: 529 VLQHEHFLRAAFIQQHIINNVRARHFAQPMGSALHDLCMKHCLDLHTPQIPEGINLGYFE 588

Query: 528 -AGLSVAADSLSAIKYAKVKP---IRDEDGLAIDFEIEGE---------YPQFGNNDPRV 574
             G     DSL+AIK    +       E   A+    EG+          P +GNND   
Sbjct: 589 YMGFGTVVDSLAAIKKLVFEDKKLTMQEVIEALKCNFEGKEDVQQMLKSAPCYGNNDEYA 648

Query: 575 DDLAVDLVERFMKKIQKLHTYR-DAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPG 633
           D +A ++ +    K  + ++           +  TS+V +GK    TP+GR A  P   G
Sbjct: 649 DSIAREI-DAISVKYGRRYSPELGMHNDVRYVPFTSHVPFGKVVSATPNGRLAWTPLSDG 707

Query: 634 ANPMHGRDQKGAVASLTSVAKLPFAYAKDGIS--YTFSIVPNALGKDDEVRKTNLAGLMD 691
           ++  HG D  G  A L S         +D  +        P  +  D+   K  L   + 
Sbjct: 708 SSASHGADVNGPTAVLQSNFSSKNYGYRDRAARMLNIKFTPKCVEGDEGTEK--LVSFIR 765

Query: 692 GYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDV 751
            +   +       H+  NV+NR+ L+ A ++PEKY  L +R++GY+  F  L+ + Q D+
Sbjct: 766 TFCDLKL-----WHVQFNVINRDTLIAAQKDPEKYRSLIVRIAGYSAYFVDLSPDLQNDL 820

Query: 752 ITRTFTQSM 760
           I RT   +M
Sbjct: 821 IARTQHDAM 829


>UniRef50_A6CWD5 Formate acetyltransferase 2 n=4 Tax=Bacteria RepID=A6CWD5_9VIBR
          Length = 843

 Score =  591 bits (1524), Expect = e-167,   Method: Composition-based stats.
 Identities = 157/781 (20%), Positives = 281/781 (35%), Gaps = 93/781 (11%)

Query: 58  VMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIK 117
           V E  +        +   TA A     H+        E I+G          + P   + 
Sbjct: 71  VTEAYRENETLPRIL--QTAFAFQNILHNCTLHVYDDELILGEIAAPAKASPIYPEFSVD 128

Query: 118 MI-EGSCK--AYNRELDPMIK----------KIFTEYR-KTHNQGVFDVYTPDILRCRKS 163
            I +         R  D              ++   ++ KT N+ +      D  +    
Sbjct: 129 WIIDEILHSPFEERSNDQFYIRNEQDKNEILELCAYWKGKTANEIITAHLDDDQKKGSHM 188

Query: 164 G---VLTGLPDAYGRGRIIGDYRRVALYGIDYLM-----------------KDKLAQFTS 203
           G     T      G G    D+ ++   G D ++                  DK   + +
Sbjct: 189 GEKIFQTNNYHFAGIGHFAMDFTKLMTLGYDGVILQANSALKDLSKQDPDYSDKRDYYKA 248

Query: 204 LQADLEN-GVNLEQTIRLREEIAEQH---RALGQMKEMAAKYGYDISGPATNAQEAIQWT 259
               LE     + +  +L  E+AE     +   ++  M+        G   +  +AIQ  
Sbjct: 249 TIVCLEAAKHYIARYAQLTSEMAEHETDAKRKQELHTMSLNCQQIAGGAPKSFWQAIQLF 308

Query: 260 YFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFL 319
            F         NG ++S+GR   +L  + ++D+    +++    E+++ L +K+     L
Sbjct: 309 NFAVTLTQIEGNGHSISYGRMDQWLLPFYQKDVNERAVSKSFILELIEVLYVKMNNPTKL 368

Query: 320 RTPEYDELFSGDPI-WATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSE 378
           +     ++ +G      + ++GG+  +G+      +   L           P + +   E
Sbjct: 369 KDKGTVKVRNGRGFGGESLTLGGVDSEGKDATNDLTMLMLEASAH-TRMMNPWVCVRMHE 427

Query: 379 KLPLNFKKFAAKVSI-DTSSLQYENDDLMRPDF--------NNDDYAIACCVSPMIVGKQ 429
           K P   K    +         +  ND                  +YA+  CV P I GK+
Sbjct: 428 KTPYELKIKTIECIRAGYGHPKLFNDTPAIKAMLGKGVSLAEARNYAVVGCVEPTIPGKE 487

Query: 430 MQFFGA-RANLAKTMLYAINGGV---DEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMD 485
             +  A   N AK M   INGG          Q+GP +  ++     +++V+E +D    
Sbjct: 488 HGWLDAGYVNTAKMMEMVINGGRILSGPNAGQQLGPDTGSLET-YTTFEQVLESVDKQFA 546

Query: 486 WLAKQYITALNIIHYMHDKYSYEASLMALHDRDVI--RTMACGI----------AGLSVA 533
           +   Q  + LN+   +H        + A  +  +   R M  G           AG++  
Sbjct: 547 YWCDQLCSCLNVTDKIHRMIKPTPYISAFFEGCIETGRDMTFGGVKYNGTAPQAAGVATC 606

Query: 534 ADSLSAIK---YAKVKPIRDEDGLAIDFEIEG-----------EYPQFGNNDPRVDDLAV 579
           ADSLS IK   +   K    +   A+     G           + P +GN++   D+L  
Sbjct: 607 ADSLSTIKKLVFDDKKYTGKQLLDAVKNNWVGYEKLYALVNSSKIPHYGNDNDEADELFT 666

Query: 580 DLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMH- 638
            + E + + I+     R    +  V T+ +NV  G  T  + DGR+   P      P+H 
Sbjct: 667 FMFECYCRHIKGRINPRGGKFSPGVYTVNANVGMGLYTNASLDGRKNEEPISDNMGPVHT 726

Query: 639 ---GRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFH 695
                D +G  A + SV K+  + A +G         +A+   +   +  L   +D Y  
Sbjct: 727 AGGSHDTQGPTAIVNSVTKVDHSLATNGTLLNLRFPEDAVSGIEG--RDILVSFIDEYIS 784

Query: 696 HEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRT 755
            +     G H+  N+M+ + +  A +NPE Y  + +RV+GY+  F  L K  Q D+I RT
Sbjct: 785 KQ-----GMHVQFNIMSSDKMRAAQKNPELYRDMLVRVAGYSAYFVELGKPLQDDLIQRT 839

Query: 756 F 756
            
Sbjct: 840 E 840


>UniRef50_B0G487 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=B0G487_9FIRM
          Length = 803

 Score =  582 bits (1501), Expect = e-164,   Method: Composition-based stats.
 Identities = 161/754 (21%), Positives = 283/754 (37%), Gaps = 95/754 (12%)

Query: 91  NKQLEKIVGLQTEAPLKRALIPFGGIKMI-EGSCKAYNRELD---------PMIKKI--- 137
            K  E IVG   +      + P    + I E       R  D         P  +KI   
Sbjct: 58  VKPGELIVGNMAKNAKSSPVFPEYSAQWILEELDGKPYRWEDRPGDKFYILPEDEKIVRE 117

Query: 138 -FTEYR-KTHNQGVFDVYTPDILRCRKSGVLTGL-PDAYGRGRIIGDYRRVALYGIDYL- 193
               +  KT    V      ++     +GV       A G G  I DY+ V   G++ + 
Sbjct: 118 CAEYWNGKTLYDYVRKNLPKEVNDAWDAGVTDETWVCAAGLGNEIVDYKMVVEKGLEDVL 177

Query: 194 --MKDKLAQFTSLQAD-LENGVNLEQTI-----------RLREEIAEQH------RALGQ 233
             +++K      L  D L+    LE              RL ++  E+           +
Sbjct: 178 TRIQEKKDSIDILDPDALKQLHFLEAAKLGNEAVLNYSNRLADKCEEEAGKTDDSEYKKE 237

Query: 234 MKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLK 293
           + E+A    Y    PA   QEA+Q  +   LA     NG A+S GR   ++    ++D++
Sbjct: 238 LMELAEICRYVPFHPARTFQEAVQSIFMVLLAVHMESNGHAISLGRFDQYVYPLYKKDIE 297

Query: 294 AGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKN 353
            G+IT+++A E+++   +K   +  LR+    E F G  ++   +I G  ++G+      
Sbjct: 298 EGRITKEKALEIIECFFIKCNELNKLRSWPDTEFFMGYQMFINLAICGQTVEGKDATNDI 357

Query: 354 SFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAK--VSIDTSSLQYEND-------- 403
           S   +     +     P++++   +         A +  +        + ND        
Sbjct: 358 SRMCIQACREL-KLITPSVSVKCFDGTTDEVLMDALEATIEHKGGMPAFYNDKAFIKILR 416

Query: 404 DLMRPDFNNDDYAIACCVSPMIVGK-QMQFFGARANLAKTMLYAINGGVDEKLKMQVGPK 462
           ++   + +  D+    C+   I GK      G   ++ K +   +N G D          
Sbjct: 417 EMGVAEEDLVDWCPDGCIEASIPGKWDFAAKGPWLSIEKVLEITLNNGKDPATGTVFRKP 476

Query: 463 SEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRT 522
            + I     + +++ E     + +         +I   +H +Y   A   +L    + R 
Sbjct: 477 DKDIVAS-SSMEDIFEEYKKTLKYFLDLNCLTEHINDEVHVRYDLNAFRSSLVQDCIGRC 535

Query: 523 MAC------------GIAGLSVAADSLSAIKYAKVK---PIRDEDGLAIDFEIE------ 561
           +                AG   A D+L+ I+Y          ++   A     E      
Sbjct: 536 LDLVEGGALYSADGGPTAGTISAGDALTGIEYLVFDKKILTMEQLLHACATNFEDESTTP 595

Query: 562 ----------GEYPQFGNNDPRVDDLAVDLVERFMKKI-QKLHTYRDAI------PTQSV 604
                      + P+FGN+D   D   V + E     +     + +            S 
Sbjct: 596 TGKEIQMIMKNKVPKFGNDDDYADKWVVAIEEYVGHSLNHDYKSSKYGKGPVPCCFAYSQ 655

Query: 605 LTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGI 664
             +T N+ +G + G TPDGR AG P   G +P +G ++ GA A+  SVAK+P  Y + G 
Sbjct: 656 TPVTGNISFGSRIGATPDGRSAGEPVNNGVSPANGSERNGATAACNSVAKIPTIYDQKGN 715

Query: 665 SYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPE 724
            +   + P+ +   +  +K  +  +M   F  +A       +  NV++ E+L +A + PE
Sbjct: 716 IFNMRLAPSTIANQESRQK--ILDMMRALFDKDAE-----QIQFNVVDNEVLKEAQKRPE 768

Query: 725 KYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQ 758
            +P L +RVSGY+  F SL    Q DVI RT  +
Sbjct: 769 DFPDLMVRVSGYSALFTSLGVACQNDVINRTEVE 802


>UniRef50_C6BT93 Formate C-acetyltransferase n=6 Tax=Desulfovibrio
           RepID=C6BT93_DESAD
          Length = 817

 Score =  578 bits (1490), Expect = e-163,   Method: Composition-based stats.
 Identities = 144/782 (18%), Positives = 270/782 (34%), Gaps = 93/782 (11%)

Query: 56  DKVMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGG 115
             + E  +              V   + +H   +++     IVG  T         P   
Sbjct: 48  KFLNEVYEKHQGEPVVY-IRAKVFERVLTHKKIFLDGN--PIVGTLTGVRAGVYAYPEWN 104

Query: 116 IKMIEGSCKAYNR----------ELDPMIKKIFTEYRK----THNQGVFDV-YTPDILRC 160
           +  I+   +              E   +++K +  ++       N  ++   Y     + 
Sbjct: 105 VSWIKEEMQMAKMASLGEMKIPAETQELLEKTYKLWKGRTCIDQNNTMYKEKYGESAKKY 164

Query: 161 RKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLENGVNLE----- 215
            K+G+          G  I DY  V   GI +L+++   + T     L N   ++     
Sbjct: 165 AKAGMYYENVSVA-SGSGIADYGLVLNKGIRHLIEEVRTRLTETPNILANRDKIDLYRSM 223

Query: 216 ------------QTIRLREEIAEQHRA---LGQMKEMAAKYGYDISGPATNAQEAIQWTY 260
                       +   L E+ A          ++ E+A         PA N +EAIQ  +
Sbjct: 224 LITFDAVIKHSHRYADLAEQTAADESDPKVKAELLEIAEICRRVPEHPARNFREAIQSFW 283

Query: 261 FGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLR 320
           F +L     Q   A+S GR   ++  + ++D+  G +T ++   M+    ++   +   +
Sbjct: 284 FTHLCVATEQMACAVSPGRYGQYMYPFFKKDIDEGNLTREQVLTMLKFQWIRHLELGEYQ 343

Query: 321 TPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKL 380
              Y    SG     + +IGG+  DG    T+     L T   M  S +P +T+L+  KL
Sbjct: 344 GNSYALTLSG-HTGQSMTIGGVDKDGNDASTELEELMLETQIQM-KSIQPTLTLLYHPKL 401

Query: 381 PLNFKKFAAKVSIDT-SSLQYENDDLMRP--------------DFNNDDYAIACCVSPMI 425
             ++ +   +         Q  N++++                  +  +     CVS  +
Sbjct: 402 KESYMQKVVECIRGGSGQPQILNNNVVIQRTLARFAQYPDGITLEDARNCGNYGCVSTGV 461

Query: 426 VGKQMQFFGAR-ANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFM 484
            GK           LAK +   +N G     K  VG ++         ++++ E +   +
Sbjct: 462 CGKGSFITQEDQPCLAKVVELVLNNGKCPVTKKMVGAETGDPTT-FETFEDLYEGVKGQL 520

Query: 485 DWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMA-------------CGIAGLS 531
           D L +      ++      +        A++D  + + M                 AG+ 
Sbjct: 521 DNLFRISRAHSDLSQMARLQVVPSVFRSAMYDGCIEKGMCEEAGGTRYPQVNPIMTAGV- 579

Query: 532 VAADSLSAIKYAKVKP---IRDEDGLAIDFEIEG---------EYPQFGNNDPRVDDLAV 579
            AA+S+ AIK+          +E   A+    EG         + P+ GN+   V     
Sbjct: 580 DAANSILAIKHLVYDTKAVTMEELIQALKANFEGYEELRQMCFDAPKHGNDYEDVQAFVQ 639

Query: 580 DLVERFMKKIQKL-HTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPG-ANPM 637
                                      +++ +  +G   G  P+GR+AG     G  + M
Sbjct: 640 RFYRDVDAIHHAQGPDCFGQRTPLDAYSLSYHNYFGGMMGALPNGRKAGVALTDGSVSAM 699

Query: 638 HGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHE 697
            G D++G  A + S A+           +     P+ L      +   L  L+  Y    
Sbjct: 700 PGTDKEGITALIKSGAEAIDTVRYGANHFNVKFSPSVLEGPQGAK--TLISLIKTYCDF- 756

Query: 698 ASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFT 757
               GG H+  N ++ + L DA +NP+ Y  L +RV+G++  F  L    Q ++I RT  
Sbjct: 757 ----GGSHIQFNCVSSDTLKDAQQNPQDYSDLIVRVAGFSAYFTRLDCGVQNEIIKRTEY 812

Query: 758 QS 759
            +
Sbjct: 813 DA 814


>UniRef50_B8J0R1 Formate C-acetyltransferase n=9 Tax=Proteobacteria
           RepID=B8J0R1_DESDA
          Length = 831

 Score =  575 bits (1482), Expect = e-162,   Method: Composition-based stats.
 Identities = 148/770 (19%), Positives = 280/770 (36%), Gaps = 96/770 (12%)

Query: 76  TAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIKMIEGSC-KAYNRELDP-- 132
                 I  +   Y+ ++ + ++G          L P      ++ +      R+  P  
Sbjct: 73  AKALMHIARNMTVYV-QEDQLLLGRAGCDGRYGILYPELDGDFLDIAVRDLPTRKTSPAT 131

Query: 133 --------MIKKIFTEYR-KTHNQGVFDVYTPDILRCRKSG--------VLTGLPDAYGR 175
                   ++++I   ++ KT+++ +      ++ +             ++         
Sbjct: 132 ITPEDARRVVEEIAPYWKGKTYHEALNAALPAEVHKLTYDDPEGLISRFIVNETSSFRSS 191

Query: 176 GRIIGDYRRVALYGIDYLMKDKLAQFTSLQA-----DLENGVNLE--------------Q 216
            + + DY ++   G + + K+   +  +L       D E    LE              +
Sbjct: 192 IQWVHDYEKILKRGFNSIKKEAREKLAALDPLSAKDDREKRPFLEAVMIVCDAIVLWAKR 251

Query: 217 TIRLREEIAE---QHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQ-NG 272
              L  E+AE         ++  MA    +    PA +  EA Q  +F  + +   Q  G
Sbjct: 252 HAVLAREMAEKESDPVRKAELLRMAENAEHVPGEPARDFWEACQSQWFTQMFSRIEQKTG 311

Query: 273 AAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRM-VRFLRTPEYDELFSGD 331
             +S GR   +   Y ++D +AGKITE +A E+++ + + +   +    +P       G 
Sbjct: 312 TTISNGRMDQYFQPYYKQDREAGKITEAQAMELLECMWVGMAEFIDMYISPTGGAFNEGY 371

Query: 332 PIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNF-KKFAAK 390
             W   ++GG   DGR      ++  L +     P   P++      + P  +    A  
Sbjct: 372 AHWEAVTVGGQTPDGRDASNDLTYLILKSKREF-PLHYPDLAARIHSRAPERYLWDVAET 430

Query: 391 VSIDTSSLQYENDDLMRPDF--------NNDDYAIACCVSPMIVGKQMQFFG-ARANLAK 441
           +   +   +  ND+ + P +           DYA++ C    +  +     G A  N A 
Sbjct: 431 IKYGSGFPKLINDEEIVPLYVSKGATFEEALDYAVSGCTEARMPNRDTYTSGGAYINFAA 490

Query: 442 TMLYAINGGVDEKLKMQ-VGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHY 500
            +   +  G  +K   Q +G ++   +     +D+             K   T   II+ 
Sbjct: 491 AVEMVLRNGRMKKYGDQKLGVETGDPRS-FTTWDQFWNAYVEQHLLFLKTAFTQQYIINK 549

Query: 501 MHDKYSYEASLMALHDRDVIRTMA--------------CGIAGLSVAADSLSAIKYAKV- 545
           +  ++  +    A+HD  +   +                   GL    DSL+A+K     
Sbjct: 550 LRAEHFAQPMGSAMHDLCMKHCIDLHQEQIPEGINLGYFEYMGLGTVVDSLAAVKKLVFE 609

Query: 546 --KPIRDEDGLAIDFEIEG---------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHT 594
             K   D+   AID + EG           P +GNND   D +  D+ +R   +    ++
Sbjct: 610 EKKLSMDKLIAAIDADFEGYEDVRALLRSAPCYGNNDEYADAIGRDI-DRISVEYGNKYS 668

Query: 595 YR--DAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSV 652
                       +  TS+V +GK    TP+GR  G P   G++  HG D  G  A L S 
Sbjct: 669 MSDLGIHNDVRYVPFTSHVPFGKVVSATPNGRTDGFPLSDGSSASHGADVNGPTAVLLSN 728

Query: 653 AKLPFAYAKDGIS--YTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNV 710
                   +D  +        P  +  +    K  L   +  +   +       H+  NV
Sbjct: 729 CTTKNMGLRDRAARMLNIKFTPKCVEGEQGTEK--LVSFIRTFCDLKL-----WHVQFNV 781

Query: 711 MNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQSM 760
           +N+  L+ A ++P+KY  L +R++GY+  F  L+ + Q D+I RT    M
Sbjct: 782 VNKGTLVAAQKDPQKYRNLIVRIAGYSAYFVDLSPDLQNDLIARTEHDVM 831


>UniRef50_B8FDB2 Formate C-acetyltransferase n=1 Tax=Desulfatibacillum alkenivorans
           AK-01 RepID=B8FDB2_DESAA
          Length = 823

 Score =  568 bits (1463), Expect = e-160,   Method: Composition-based stats.
 Identities = 155/787 (19%), Positives = 276/787 (35%), Gaps = 92/787 (11%)

Query: 49  EATTTLWDKVMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKR 108
           E  + L++          +   P +    + + I       I    E I+G  +   +  
Sbjct: 48  ERPSLLFEFWESKNGKAAKNLHPAEARALMLAHIMRRRRPRIY-NHELIIGNMSSKRIGA 106

Query: 109 ALIPFGG-IKMIEGSCKAYNRELD-----PMIKKIFTEYRKT----------HNQGVFDV 152
              P GG + ++E      NR++          ++     K+             G F  
Sbjct: 107 NFYPEGGSLNILEDLLHLENRQIPFKLAPMEKAELLRLGLKSIPVSIGGKALLKPGRFSH 166

Query: 153 YTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGI--------DYLMKDKLAQFTSL 204
           +       R       + +  G     G+Y  V  +G+        D L  D L   T L
Sbjct: 167 FLDFFRAKRY-----FVTEEAGISHQAGNYGEVVSHGLVKADLYARDRLKADALEDGTRL 221

Query: 205 QADLENGVNLEQTIRL-REEIAEQH---------------RALGQMKEMAAKYGYDISGP 248
            AD        +TI L    +A                      ++ E A    +    P
Sbjct: 222 NADQRAFYKSVRTIILGIRNMASNLAAEAEKKAAAQGVALERRKELLEAAEACLHAPYYP 281

Query: 249 ATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDH 308
           A   +E +Q  +  ++A         +SFGR    L    + DLK G +T ++A E++  
Sbjct: 282 ARTFKEGLQACWLVHMAMNLEDFEQGLSFGRLDRILLPLYKADLKKGLLTYEKAVEIMAS 341

Query: 309 LVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSP 368
             +K      + +   D+ FSG+ +    ++GG+   GR    + S   L+    +  + 
Sbjct: 342 FQLKTCETIPIYSERIDQYFSGNGVAQGITVGGVNGGGRDCTNELSGLVLDAFSQI-KTR 400

Query: 369 EPNMTILWSEKLPLNFKKFAAKV-SIDTSSLQYENDDLMRPDFN--------NDDYAIAC 419
           EP + +   +K P  F + AA V ++      +  D  +               DYA+  
Sbjct: 401 EPALHVRVHKKTPPWFLEKAAAVAALGCGKPSFFGDKAVIKALENTGMSKPHARDYAVIG 460

Query: 420 CVSPMIVGKQMQFFG-ARANLAKTMLYAINGGVDEKLKMQVGPKSEPIK---GDVLNYDE 475
           CV     G+       A  NL   +  A+N G     +     +         ++  +D+
Sbjct: 461 CVEMASQGRTYNSSDAALFNLPLCLELALNQGYRFGSRRIPALRFGAPTPSVEEMDAFDQ 520

Query: 476 VMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMA----------- 524
           V+      +     + +  + +I   +  +        +    +                
Sbjct: 521 VLRAFKTQVRDSVNEMVKVITMIEQAYRVHRTTPVNSIITQGCLECGKDVTWGGAMYDLT 580

Query: 525 -CGIAGLSVAADSLSAIKYAKVKPIRD-------------EDGLAIDFEIEGEYPQFGNN 570
               AGL+ A DSL A+K       R              E    +  EI  ++P++GN 
Sbjct: 581 SVQAAGLADAGDSLYALKRVVFDEKRMSLKAFVDILKSNWEGQEKLRQEISQKFPRYGNG 640

Query: 571 DPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPF 630
           D   D +     + +   +      R       + ++T +  +GK TG  P+GR AG   
Sbjct: 641 DKDADRMTQVAADAYTDAVTAHKNSRGGQYIAGIYSMTCHHGFGKATGALPNGRPAGYRL 700

Query: 631 GPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLM 690
             G +P+ G D+KG  A L S A L  +   +  +       N        +   L+GL+
Sbjct: 701 SNGLSPVDGVDKKGPTAVLQSAASLDSSQWGNCCALNIKFDGNQFKGTKGAKI--LSGLI 758

Query: 691 DGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQD 750
             Y +      GG  +  N+++ E L +A E+P  +P + +RV+GY   FN L    Q +
Sbjct: 759 TAYMNM-----GGMQIQPNILDAETLREAKEDPSAHPGIVVRVAGYCAYFNDLQPMVQDE 813

Query: 751 VITRTFT 757
           VI+RT  
Sbjct: 814 VISRTSH 820


>UniRef50_Q30WU7 Formate C-acetyltransferase n=1 Tax=Desulfovibrio desulfuricans
           subsp. desulfuricans str. G20 RepID=Q30WU7_DESDG
          Length = 811

 Score =  565 bits (1457), Expect = e-159,   Method: Composition-based stats.
 Identities = 152/780 (19%), Positives = 261/780 (33%), Gaps = 90/780 (11%)

Query: 58  VMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIK 117
           +ME  K     H            I       I+   + + G  +  P+     P     
Sbjct: 42  LMESYKETESLHF-FRRRGKAIRKILQEMPIRID-DHQLLCGDFSAKPMGPEFFPDLAAT 99

Query: 118 MIEGSCKAYN--------RELDPMIKKIFT----EYRKTHNQGVFDVYTPDILRCRKSGV 165
            I      Y         R  D    +I       +R+T  +  +  +  D     +  +
Sbjct: 100 WIVDYIDNYGVEGRKGFFRWEDEEQMEIGRSIGEYFRETGGKEKWIAFLGDEEAALEHKI 159

Query: 166 --------LTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTS-------------- 203
                    T       +     D  R+   G+  L+ D   Q                 
Sbjct: 160 GEAGSWIVNTVSEMFAEKAWNCPDLDRLVKRGVRGLIADIDEQLEKFVMITYEDYRRHEF 219

Query: 204 ----LQADLENGVNLEQTIRLREEIA---EQHRALGQMKEMAAKYGYDISGPATNAQEAI 256
                +  L       +   L  E+A          +++EMA         PA   QEA+
Sbjct: 220 WLGLKEMLLGGIDYAHRYRDLATELAAKETDPVRKAELEEMARVCNRVPEHPAETFQEAL 279

Query: 257 QWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMV 316
           Q   FG L          M +GR    +    + D+ +GKI ++   ++ +   +K+   
Sbjct: 280 QSLVFGLLMVFYDTRTFGMGYGRIDQIMYPQYKSDIASGKIDDEYVVQLFECFRVKIMGK 339

Query: 317 RFLRTPEYDELFSGDPIWATESIGGMGL-DGRTLVTKNSFRFLNTLYTMGPSPEPNMTIL 375
           R           S +  +    I G+    GR    + SF FL     +  +  P +++ 
Sbjct: 340 RQFWPDVMTPNLSSESHFHNCVICGVDPKTGRDATNELSFAFLEAAERV-RTTHPTISVR 398

Query: 376 WSEKLPLNFKKFAAK-VSIDTSSLQYENDDLMRPDF--------NNDDYAIACCVSPMIV 426
           W  ++   F K A + V +      + ND+                 +YA+  C    + 
Sbjct: 399 WHTQIDPKFMKRALETVKLGMGFPAFFNDEPSIQYLLARGYTMEEARNYALGGCTLHTVP 458

Query: 427 GKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDW 486
           GK    +    +  + +   +  G D     Q+GPK+      + +Y+E +      +++
Sbjct: 459 GKTSSIWPLVTSYGRILELTMYNGWDFISNSQLGPKTGDFT-QMTSYEEFVAAYKAMIEY 517

Query: 487 LAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAG--------------LSV 532
            A     +       H     +  + A  D  + R   C + G              +  
Sbjct: 518 WANVSTKSGRAAKLQHGDTFPDIMMSAFTDDCIGRGKVCSLGGAEHADSCMYIVPVAVQD 577

Query: 533 AADSLSAIKYAKVKP----IRDEDGLAIDFEIEGE---------YPQFGNNDPRVDDLAV 579
            A+ L  +K+            E   A+    EG           P+FGN+ P VD L  
Sbjct: 578 VANELYVLKHGVFGENPICTPQEMLDAMRANWEGHEELRAKCMAMPKFGNDIPEVDQLLT 637

Query: 580 DLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPG-ANPMH 638
           D+     +               S  +I  +   G KTG  P GR+AG  F  G  +P+ 
Sbjct: 638 DVYNWIKEIWHAQPATDGGRYEVSPHSIGFHGGTGAKTGALPCGRKAGTSFSDGAVSPVQ 697

Query: 639 GRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEA 698
           G D  G  A + S   +       G+ +     P+ +  +      NLA L+  YF    
Sbjct: 698 GTDVNGPSAVIKSAGSIDQHDLY-GVLFNMRFSPSNIRGEKGT--ANLASLIKTYF---- 750

Query: 699 SIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQ 758
           S   G+H+  NV+NR+ L+ A + PEKY  L +RV+GY+  +  L    Q ++I RT  +
Sbjct: 751 SDYKGKHIQFNVLNRDDLIAAKKEPEKYKDLMVRVAGYSAYWTDLPANIQDELIARTEHE 810


>UniRef50_D2LJ70 Formate C-acetyltransferase n=1 Tax=Rhodomicrobium vannielii ATCC
           17100 RepID=D2LJ70_RHOVA
          Length = 829

 Score =  561 bits (1447), Expect = e-158,   Method: Composition-based stats.
 Identities = 166/784 (21%), Positives = 274/784 (34%), Gaps = 92/784 (11%)

Query: 48  TEATTTLWDKVMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLK 107
           TE  T L D   E           +     V   +      YI      +VG  T  P  
Sbjct: 58  TERLTHLLDVYREY-----AQEPVIVLRARVFERVLQKKTLYI--DDNPLVGTVTSKPAG 110

Query: 108 RALIPFGGIKMIEGSCKAY------NRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRCR 161
               P  G + I               EL    +    E  K       +    ++ R  
Sbjct: 111 VYPYPEWGAEWILREADQPMVSHLGEVELSDEERATLIETAKYFQTRSAEARARELSREL 170

Query: 162 K--------SGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLENG-- 211
                    +  L      Y  G    DY      G+  ++++   +  +L    EN   
Sbjct: 171 HGFDPRDSVAAGLITETAPYTIGSGTLDYATFIRRGLGDIIRETEGRLKALPLTQENASK 230

Query: 212 ---------------VNLEQTIRLREEIAEQ---HRALGQMKEMAAKYGYDISGPATNAQ 253
                              +   L E++A +        ++ E+A    +    P  N +
Sbjct: 231 IDFYRAVLISLNALIHLAHRYADLAEKLAAETGDAVRRAELLEIAEVCRHVPENPPRNFR 290

Query: 254 EAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKL 313
           EAIQ+ +F +L     Q+G   S GR   +LD + + D      T ++AQ     L +K+
Sbjct: 291 EAIQFWWFLHLGNQIEQSGCGSSPGRIGQYLDPWFQADKAQNGFTREDAQAWFKCLFVKI 350

Query: 314 RMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMT 373
               + +        SG     T ++GG+   G+   T+     L+T   +  + +P +T
Sbjct: 351 LEYGYYQGLISARTNSG-HTGHTINLGGLNAAGQDATTELDSVLLDTQIEL-QNIQPTIT 408

Query: 374 ILWSEKLPLNFKKFAAKVSI-DTSSLQYENDDLMRP------------DFNNDDYAIACC 420
           IL+ + L  +F   A ++        Q+ N  L+                +        C
Sbjct: 409 ILYHDGLQEDFLLKAIELERTGLGQPQWMNTRLIIERTLARHAKNGITIEDARASINMSC 468

Query: 421 VSPMIVGKQMQFF-GARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMER 479
           V   + G+      G   NLAK +  A++ G+D      VG ++   +    ++++    
Sbjct: 469 VGTGVEGRTAFIHEGGTFNLAKCIELALHDGIDPGTGFFVGARTGDARS-FKSFEDFYGA 527

Query: 480 MDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGL--------- 530
               ++ L K      ++      +    A   AL+   + R       G+         
Sbjct: 528 WLRQVEHLFKVQRAFGSVSTKALGETIAPAFRSALYGGCLERGKHVFDGGVDYYLYFVIS 587

Query: 531 ---SVAADSLSAIKYAKVK---PIRDEDGLAIDFEIEG---------EYPQFGNNDPRVD 575
                AA+SL+AIK+           E   A+D   EG           P+ GN DP +D
Sbjct: 588 NAGVDAANSLAAIKHLVFDTGRLTLGELLDAVDANFEGHDRIRTLCLNAPKHGNGDPAID 647

Query: 576 DLAVDLVERFMKKIQ--KLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPG 633
            L   + +   K         + D I      +++ +  YG KTG  P GR+ G P   G
Sbjct: 648 ALVRRVYDDAFKTFHAAGYSYFGDHIANIEAYSLSIHNYYGLKTGALPSGRQKGRPLTDG 707

Query: 634 -ANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDG 692
             +   G D+KG +A + S A+   A       +     P AL      RK  L  L+  
Sbjct: 708 SVSATPGTDKKGPLALIQSAAQAVDAVKYGSNHFNMKFHPTALAGIGGARK--LLSLIKT 765

Query: 693 YFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVI 752
           Y        GG H+  NV+  + L  A  NP+ Y  LT+RV+G++  F  L K  Q ++I
Sbjct: 766 YMDA-----GGSHIQFNVVTSDTLRKAQANPDAYKGLTVRVAGFSAYFTRLHKGVQDEII 820

Query: 753 TRTF 756
            RT 
Sbjct: 821 ERTE 824


>UniRef50_B1BA70 HpdB protein n=1 Tax=Clostridium botulinum C str. Eklund
           RepID=B1BA70_CLOBO
          Length = 841

 Score =  553 bits (1425), Expect = e-156,   Method: Composition-based stats.
 Identities = 140/710 (19%), Positives = 261/710 (36%), Gaps = 108/710 (15%)

Query: 131 DPMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGI 190
           +  +K+   EYR   N     +Y P ++   +             GR +  Y  V   G+
Sbjct: 156 EKFLKETMPEYRDLVNAFKTVLYPPSVISIME-------------GRWVPAYDIVVEKGL 202

Query: 191 DYLMKDKLAQ----FTSLQADLENGVN-------LEQTIRLREEIAEQH----------R 229
           D ++ +          + +   E  +         E  I   +  A +            
Sbjct: 203 DAVIDECKDNIKNTLPTTREVAEKVIFWKSVILVCEGVINWAKNYANEALSMASKETNDE 262

Query: 230 ALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIE 289
              ++ +MA    +  + PA    E +Q  +  ++A         +S GR    L    +
Sbjct: 263 RKKELLKMAETLNWVPAKPARTFYEGLQAAWTAHIAVSLDGPIVGLSPGRWGQLLYPLYK 322

Query: 290 RDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTL 349
           +DL+ G +  +EA E+++ + +K     ++    ++ L SG  ++    +GG+   G   
Sbjct: 323 KDLEKGLLKREEAVELMELIRVKFSSEEYVSPRSWEALASG-NLFQHMIVGGVDSKGNCS 381

Query: 350 VTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSI-DTSSLQYENDDLMRP 408
                   L    +M  + +P + ++++ K        AA+ +   +    + N++    
Sbjct: 382 DNDLEEIILEAGTSM-QTIQPTLGVMFNSKTSNKLLMKAAECTKTGSGYPAWFNNEKCIE 440

Query: 409 DF------------NNDDYAIACCVSPMIVGKQMQ-FFGARANLAKTMLYAINGGVDEKL 455
                         +  D AI  CV   + G        A  N  K +   +N G+D + 
Sbjct: 441 HLLQNHQEENITIEDARDVAIGGCVEVQMQGNCHGICHPAFFNELKCLEIVLNDGIDPRT 500

Query: 456 KMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALH 515
            ++         G    ++++        +   K Y+   N +  +H + +       L 
Sbjct: 501 GIRC----FEPLGTFDTFEDLWAAWCKVEEKYLKVYMHYWNYVLAVHREINPLIMGSVLV 556

Query: 516 DRDVIRTM-------------ACGIAGLSVAADSLSAIK---YAKVKPIRDEDGLAIDFE 559
              +                     +G+   A+SL+AIK   Y   +   ++  +A+   
Sbjct: 557 KDCLSEGKPLDSNGARYNKTITLLNSGMVNVANSLAAIKKLVYEDKQYSINDLKIALKNN 616

Query: 560 I-----------------------------EGEYPQFGNNDPRVDDLAVDLVERFMKKIQ 590
                                             P+FGN+D  VD + VDL E +     
Sbjct: 617 FGFESADKTGNFSMLEQKCMDSTYKRLHNDLLNTPKFGNDDDYVDTIFVDLWEHYNNTCL 676

Query: 591 KLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGA-NPMHGRDQKGAVASL 649
              TY       + L+I+++  +G+    TPDGR AG     G  +   G D+ G +A L
Sbjct: 677 SETTYLGLQWIPAALSISAHGPFGRVCSATPDGRVAGVSLTDGILSATPGTDKNGPIALL 736

Query: 650 TSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVN 709
            S  KL     +  +     + PNA+   D  +K  L  L+  YF      +GG H+  N
Sbjct: 737 NSGVKLDSVKMR-SVQLNMKLHPNAIKNVDGSKK--LVNLIRTYFE-----QGGYHIQFN 788

Query: 710 VMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQS 759
           V++ ++L DA  NPEKY  L +RV+G++  +  L+K  Q ++I RT   S
Sbjct: 789 VVDSKILRDAQHNPEKYRDLIVRVAGFSAYWVELSKPIQDEIIARTEYTS 838


>UniRef50_A6G8C6 Pyruvate formate-lyase 2 (PflD) n=1 Tax=Plesiocystis pacifica SIR-1
           RepID=A6G8C6_9DELT
          Length = 889

 Score =  551 bits (1420), Expect = e-155,   Method: Composition-based stats.
 Identities = 145/786 (18%), Positives = 276/786 (35%), Gaps = 133/786 (16%)

Query: 79  ASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGG-IKMIEGSCKAYNRELDPMIKKI 137
            + +  H    +    E I+G  T   +  A+ P  G + M+    +   REL+P+    
Sbjct: 105 FAHVLGHMQLRVYPD-ELIMGNPTAHRIGSAIHPEYGGMLMLPELDQLTRRELNPLAAT- 162

Query: 138 FTEYRKTHNQGVFDVYTPDILRCRKSGVL--------------TGLPDAYGRGRIIGDYR 183
             E  +     +   +    +  R   +                 L    G   ++ DY 
Sbjct: 163 -DEQLRRLEDDILPWWFTCSILSRAPLLAADKLLQNRLVEARDFVLTQFAGIAHVVPDYP 221

Query: 184 RVALYGIDYLMKD-------------KLAQFTSLQADLENGVNLEQTIRL---REEIAEQ 227
            V   G+  ++++             +     +           ++  R      E+AE 
Sbjct: 222 TVLRLGLRGVLEELRAAQRHAQSSEQREFYEAATICVTAAMDFAQRQARFVAGAAEVAED 281

Query: 228 HRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVY 287
                +++E+AA        PA    EA+Q  +  ++   +      +SFGR   +L  +
Sbjct: 282 PERAAELRELAAVLARVPIEPARTYHEALQSVFTTHVVIHQESFQHGISFGRIDQYLAPF 341

Query: 288 IERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLD-G 346
           ++ DL+AG++ E  A E+    + K      L      E FSG    +  ++GG     G
Sbjct: 342 LDADLEAGRLDEARAVELTGCFLAKAAEQLPLFNAMSTEFFSGLSSASGLTLGGTDPRTG 401

Query: 347 RTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSI-DTSSLQYENDD- 404
               T  +   L   + +    +PN+ +      P   ++ A  V            D+ 
Sbjct: 402 ADATTSVTRAILLAYHQL-RLRQPNLHLRVHPGTPEGLRRLAYAVLREGGGMPALFRDEG 460

Query: 405 -------LMRPDFNNDDYAIACCVSPMIVGKQMQFFG-ARANLAKTMLYAINGGVDEKLK 456
                  L  P    +DYAI  CV   +  +     G A  +L   +        D  ++
Sbjct: 461 VVDAIRGLGVPHEAAEDYAIVGCVEWGVPYRSFPAAGAAFVSLPAIL-------RDLLME 513

Query: 457 MQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHD 516
               P        + + D+V       ++   ++ +   + I   H +Y     L A+  
Sbjct: 514 EHEPP--------LRDMDDVWAAFRAAVEARIEEVVAGNDAIERAHAEYRPTPMLSAVVR 565

Query: 517 RDVIRTM------------ACGIAGLSVAADSLSAIKYAKVKPI---------------- 548
               R                   G++  ADSL+ ++     P                 
Sbjct: 566 GCAARGKDVCAGGADFNSTGVQAVGVADVADSLTVLEQLVFPPPGGGRPELSRGRGIGPR 625

Query: 549 -----------------------------RDEDGLAIDF--------EIEGEYPQFGNND 571
                                        R    LA DF         +    P++G + 
Sbjct: 626 GRALGRDGFHHRLLERTGTVKSSQSLSLGRLRRALARDFVDEEALRQRLRNHVPKYGQDA 685

Query: 572 PRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFG 631
              +  A  + E + + +++    R         ++T++V +G++ G  P GR+AG P  
Sbjct: 686 GPPERWARRVAELYAELLREHLNPRHGPYAPGFWSMTTHVGFGRRLGALPSGRKAGRPLA 745

Query: 632 PGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMD 691
            G +P  G D +G  ASL SVA +   +  +G +   ++ P+ +  +  +    +  L+ 
Sbjct: 746 NGLSPSSGADNRGPTASLLSVAAVSGGFVGNGYALNETLDPSFVRGEVGL--ARIDQLVR 803

Query: 692 GYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDV 751
           GYF       GG  +  NV++   L+DA  +PE++  L +R+SGY+  FN L++  + ++
Sbjct: 804 GYFAA-----GGNQVQFNVLDTAELVDAKAHPERHRGLVVRISGYSAYFNDLSEAMKDEL 858

Query: 752 ITRTFT 757
           I R+  
Sbjct: 859 IARSRH 864


>UniRef50_B8FHW6 Formate C-acetyltransferase n=2 Tax=Desulfobacteraceae
           RepID=B8FHW6_DESAA
          Length = 1000

 Score =  543 bits (1400), Expect = e-153,   Method: Composition-based stats.
 Identities = 142/745 (19%), Positives = 269/745 (36%), Gaps = 89/745 (11%)

Query: 90  INKQLEKIVGLQTEAPLKRALIPF-GGIKMIEGSCKAYNRELDPMIKKIFTEYRKTHNQG 148
           I ++ + + G  T   +   + P   G  +        +R L+P    +  +  +  +  
Sbjct: 266 IIRKDDLLAGTSTTKEVGVIVYPDAHGTMLWGELYTVPHRSLNPY--DVSEDTVRLLHHE 323

Query: 149 VFDVYT----PDILR------------CRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDY 192
           VF  +T     + +R             R +               I D+ ++   G   
Sbjct: 324 VFPYFTHRNFKEWVRYNYQSPLCQAIDERYAVYFVW--KQAALSHTIPDFPKILSLGASG 381

Query: 193 LMKDKLAQFTSLQADLENGVNLEQTIRLREEI-----------------AEQHRALGQMK 235
           ++ +   +             LE  I   E +                     +   +++
Sbjct: 382 VINEIKGKLNQEGLSDRQKGLLEGMIHSMEGMIAYSKNLSAQAAEEAAQESDPKRKAELE 441

Query: 236 EMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKA- 294
            +A      +  PA N  EA+   +  ++        A +S GR   +L  Y E DL+  
Sbjct: 442 NIAQACAQVVENPARNLDEAVNAVWITWVGMHMENTNAGLSMGRLDQWLQPYYETDLEKI 501

Query: 295 --GKITEQ---EAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTL 349
             GK  E     A E+V  L M+      L     +  F G       ++GG+  +G+  
Sbjct: 502 SDGKEREAYIKHAIELVGCLFMRCTDHLPLTPDLANWYFGGSSSDQAITLGGVTPEGKDA 561

Query: 350 VTKNSFRFLNTLYTMGPSPEPNMTILWS-EKLPLNFKKFAAKVSIDTSS-LQYENDDLMR 407
           V   ++ FL     +G   +PN+   ++ EK    + K   +V++ T++     +D  + 
Sbjct: 562 VNDMTYIFLKVTEMLGIR-DPNVNARYNREKNSDAYLKRLCEVNLITAATPSLHSDQAVI 620

Query: 408 PDF--------NNDDYAIACCVSPMIVGKQMQFFGA-RANLAKTMLYAINGGVDEKLKMQ 458
                      + ++++   CV P + G+ +        N+   +  A+N G+   +  +
Sbjct: 621 ESLKEFDYAQEDLNNWSATGCVEPTLSGRHIGHTNFQMMNMVAALEMALNNGLHPLMNWR 680

Query: 459 VGPKSE-PIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDR 517
           +GP++  P +G    +D+  E       +L  Q +   N++   H        L +L D 
Sbjct: 681 LGPETGEPAQGAFKTFDDFFEAFTKQFAFLIDQSVEYNNLMGLAHQAIRPTPFLSSLIDD 740

Query: 518 DV------------IRTMACGIAGLSVAADSLSAIKYAKVKP---IRDEDGLAIDFEIE- 561
            +              +      GL+   DSL AIK            +   A+    + 
Sbjct: 741 CISTAADVTHGGARYNSSGAACIGLADVTDSLMAIKKLVYDDKSVSFADLKNAVADNFQS 800

Query: 562 ---------GEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVV 612
                     + P FG+      ++A  + +           YR    T    +++++V+
Sbjct: 801 EPALHALITHKVPLFGSGSEEAVEMANRVAKFAHDHYGTHTNYRGGKYTVGFWSMSNHVI 860

Query: 613 YGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVP 672
           YG  +G  P G+  G PF PG  P         + ++  VA+L   Y  + +++   IVP
Sbjct: 861 YGTLSGALPSGKLEGKPFTPGLTPQP-IASPNLLDNIRDVARLSPKYITNNLAFNVKIVP 919

Query: 673 NALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIR 732
                  E    N+   +  YF       GG  + +N +  + L DAM NPE Y  L +R
Sbjct: 920 GP-NDTHEQTVDNMFSYVKTYFDL-----GGMQMQLNAVTSDTLKDAMANPENYRNLLVR 973

Query: 733 VSGYAVRFNSLTKEQQQDVITRTFT 757
           +SGY   F +L ++ Q ++I R   
Sbjct: 974 ISGYNAYFVTLNRDMQLELIERAQY 998


>UniRef50_A5CZF4 Pyruvate-formate lyase n=1 Tax=Pelotomaculum thermopropionicum SI
           RepID=A5CZF4_PELTS
          Length = 835

 Score =  540 bits (1392), Expect = e-152,   Method: Composition-based stats.
 Identities = 151/799 (18%), Positives = 290/799 (36%), Gaps = 117/799 (14%)

Query: 66  NRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTE-----------APL-------- 106
                P+D   A A      +   + +  E IVG  T+            P         
Sbjct: 47  ETEGLPLDIRWAKAFEKKMLECPIVIRDGELIVGSNTKFIRGNSTLVAMKPREILAMCES 106

Query: 107 -----------KRALIPFGGIKMIEGSCK---AYNRELDPMIKKIFTEYRKTHNQGVFDV 152
                         + P   ++ ++   +    +  + D + + I  E    H   +FD 
Sbjct: 107 GRFDRKSSDISAVNIDPE-DLRKLKEDAEYWVEHMPKYDAVNEAIRAELGDDHFDLMFDH 165

Query: 153 -YTPDILRCRKSGVLTGLPDA--YGRGRIIGDYRRVALYGIDYLM---KDKLAQFTSLQA 206
               +    R         +   +G G  +   +     G++Y++   KD+L +   L A
Sbjct: 166 GMIYEGRAVRHHRDRGLFQNWGAFGGGNCMPT-KPAIDNGLNYIIALAKDELNRMEKLGA 224

Query: 207 DLENGV----------------------NLEQTIRLREEIAE---QHRALGQMKEMAAKY 241
            ++                           E+   L  + AE         ++ ++A   
Sbjct: 225 FVQGAASNAFRKYNLLKAIIISCNAVIKFAERHAELARKQAESCTDPVRKAELLKIAEVC 284

Query: 242 GYDISGPATNAQEAIQWTYFGYLAAVKSQNGAA-MSFGRTSTFLDVYIERDLKAGKITEQ 300
               +    N  EA+Q   F +LAA K       +  GR    L  Y ++D+  G +T Q
Sbjct: 285 QNVPANRPRNFWEAVQSLRFLHLAAWKESTERPEVGVGRIDQILYPYYKKDIDEGTLTRQ 344

Query: 301 EAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNT 360
           +A E++  L +K+R    L T + +   +   +    ++GG    G  L+ + S+  L  
Sbjct: 345 DAAELLGALWLKIRETENLVTIKREHRAAPGTLLPNVTLGGRNELGEDLINEVSWIVLEV 404

Query: 361 LYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSI--DTSSLQYENDDLM--------RPDF 410
           +       EP + I + + +  +F   A + +      +  + ND+L          P  
Sbjct: 405 MRQ-TKLSEPAIYIRYHDGIDEDFMIHALECNRDFGGGNPAFLNDELGTQRYLARGVPLK 463

Query: 411 NNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDV 470
           +  ++  + C+   +   + Q      N AK     +  G D +   Q+G K+  +    
Sbjct: 464 DAVNWNASGCLGYHLDCGEHQGGFFSLNHAKIFEITLYNGFDPRTGKQLGLKTGDVT-KF 522

Query: 471 LNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMA--LHDRDVIRTMA---- 524
            +  + ++     +D+  ++      I   +  + S  + L A  L++  +   +     
Sbjct: 523 TSLQQFIDAFYKQVDYFCERLRKHYFIWWCVEQEISPMSGLRAAMLYEDCIPAGLCSREG 582

Query: 525 -----------CGIAGLSVAADSLSAIKYAKVKP---IRDEDGLAIDFEIEG-------- 562
                       G  G++  ADSL+AI++           E   A+    EG        
Sbjct: 583 GARYPSLRSSWIGDRGITDIADSLAAIQHLVFDTKQVTMAELLDAMRNNWEGKEELRQMC 642

Query: 563 -EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTY-RDAIPTQSVLTITSNVVYGKKTGNT 620
              P++GN++   D+L  +L+    + +Q          P         ++  G   G  
Sbjct: 643 LNAPKYGNDEDLPDNLFGELMFGTQRIMQSRPDPITGEKPILFKGAAAGHITQGASVGAL 702

Query: 621 PDGRRAGAPFGPGAN-PMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDD 679
           P+GR A  P    A+  M G D  G  A + S  K  +A+   G ++        L   +
Sbjct: 703 PNGRFAYKPLNDAASSAMPGMDVNGPTAVINSATKGNYAFEYVGFTHNMKFSKQTLNTPE 762

Query: 680 EVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVR 739
           +++K  L  ++  +F       GG H+  N+ + E LLDA ++PE+Y  L +RV GY+  
Sbjct: 763 KLKK--LINILKTFFK-----RGGWHIQFNIHSVEELLDAQKHPERYRNLLVRVGGYSAY 815

Query: 740 FNSLTKEQQQDVITRTFTQ 758
           F  L  E Q++++ RT  +
Sbjct: 816 FIDLPPELQEEIVQRTMHE 834


>UniRef50_B5I3J0 Truncated formate acetyltransferase n=8 Tax=Bacteria
           RepID=B5I3J0_9ACTO
          Length = 680

 Score =  531 bits (1367), Expect = e-149,   Method: Composition-based stats.
 Identities = 311/541 (57%), Positives = 385/541 (71%), Gaps = 13/541 (2%)

Query: 5   NEKLAT-AWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLWDKVMEGVK 63
           +++ AT AW GF    W+  V+VRDFIQ N+TPYEGD SFL G T+ T  +W+ V     
Sbjct: 145 DDRTATDAWRGFAGTGWRERVDVRDFIQANFTPYEGDASFLTGPTDRTRAVWETVSALF- 203

Query: 64  LENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIKMIEGSC 123
            E R+   +D DTA  STITSH  GYI++  E IVGLQT+APLKRA++P GG++M+E   
Sbjct: 204 PEERSRGVLDVDTATPSTITSHAPGYIDRDRELIVGLQTDAPLKRAIMPNGGLRMVENGL 263

Query: 124 KAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYR 183
           +AY  E DP + ++F  YRKTHN GVFD YTP++   RK+G++TGLPDAYGRGRIIGDYR
Sbjct: 264 EAYGYEPDPFVTRVFGTYRKTHNDGVFDAYTPEMRAARKAGIITGLPDAYGRGRIIGDYR 323

Query: 184 RVALYGIDYLMKDKLAQFTSLQADLENGVNLEQTIRLREEIAEQHRALGQMKEMAAKYGY 243
           RVALYG D L++ K     + +A L+   +    IR REE+AEQ RALG++ EMAA YG 
Sbjct: 324 RVALYGTDRLIEAKR----AERALLDVRPSTADVIRDREELAEQTRALGELSEMAATYGC 379

Query: 244 DISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQ 303
           D+S PAT A EA+QW Y GYLAAVK QNGAAMS GRTSTFLDVY+ RDL  G I E  AQ
Sbjct: 380 DVSRPATTAHEAVQWLYLGYLAAVKEQNGAAMSLGRTSTFLDVYLRRDLTDGLIDESRAQ 439

Query: 304 EMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYT 363
           E++D  V+KLR+VRFLRTPEYD LFSGDP W TESIGGMG DGRTLVT+ SFRFL TLY 
Sbjct: 440 ELIDDFVIKLRIVRFLRTPEYDALFSGDPTWVTESIGGMGADGRTLVTRTSFRFLQTLYN 499

Query: 364 MGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNNDDYAIACCVSP 423
           +GP+PEPN+T+LWS +LP  FK+F A+VSIDTS++QYE+DDL RP    DD AIACCVS 
Sbjct: 500 LGPAPEPNLTVLWSPRLPTGFKEFCAQVSIDTSAVQYESDDLTRP-RTGDDTAIACCVSA 558

Query: 424 MIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHF 483
           M VG+QMQFFGAR NLAK +LYA+NGG DE    Q+ P + P+ G+ L+YDE+    D  
Sbjct: 559 MAVGRQMQFFGARVNLAKALLYAVNGGRDEMTGDQIAPPTPPLTGEYLDYDELSAAYDRV 618

Query: 484 MDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVAADSLSAIKYA 543
           +DWLAK Y+ ALN+IH     ++ +  L A  D    RT  C  A   VA+ +  + + A
Sbjct: 619 LDWLAKTYVDALNVIHL----HARQVRLRARGDGA-ARTTPC-TASWPVASPACRSPRTA 672

Query: 544 K 544
            
Sbjct: 673 C 673


>UniRef50_B8FEM4 Formate C-acetyltransferase n=5 Tax=Proteobacteria
           RepID=B8FEM4_DESAA
          Length = 832

 Score =  509 bits (1312), Expect = e-142,   Method: Composition-based stats.
 Identities = 140/769 (18%), Positives = 274/769 (35%), Gaps = 101/769 (13%)

Query: 74  FDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIKMIEGSCKAYNRELDPM 133
                 + +      +I    +  VG     P        G   + E +        +P 
Sbjct: 78  RRAKAIAHVLDKKTIFITDHAQL-VGYFGSLPNTIMWRVDGASMVNEEAYNEPGIMPEPE 136

Query: 134 IK------KIFTEYR-KTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVA 186
            +      ++   +  +T    V  +  P+      SG +     +   G    DY  + 
Sbjct: 137 NESLQKVAELNDYWAGQTAVDKVARILDPEDAVKFLSGAIGWGAPSSAYGYSGKDYEYLF 196

Query: 187 --LYGIDYLMKD-------------------------KLAQFTSLQADLENGV-NLEQTI 218
               G + ++++                         +L  + ++   LE G+ + ++  
Sbjct: 197 AGRRGFEDIIEEINAAIEKAEDKTVGVPGPEILDIYDRLQNWDAMILVLEAGIRHAKRYA 256

Query: 219 RLREEIAEQ----HRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAA 274
           RL   +AE      +   ++ ++A       +    N QE++Q+ +F  + A        
Sbjct: 257 RLARTMAENMETDEKRREELLKIAETCERVPARAPRNLQESLQYDHFIQIFARTEA-HEG 315

Query: 275 MSFGRTSTFLDVYIERDLK-AGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPI 333
               R   +   Y ++D+     +T+++A ++V   +++   V         E   G   
Sbjct: 316 AWPARPDYYHGPYYDKDVNVDKTLTKEDALDLVGEFMIRAYEVGGFAPRWAREGLQGITG 375

Query: 334 WATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKV-S 392
               ++GG+  DG       +  FL     +     P     W  K+     +   +   
Sbjct: 376 TWVWTLGGVNKDGSDACNDLTVAFLQAAR-LVRVSNPTFGFRWHPKVKDEVLRECFECIR 434

Query: 393 IDTSSLQYENDDLMR---------PDFNNDDYAIACCVSPMIVGKQ----MQFFGARANL 439
                    ND L+          P      +    C+SP    K     M+   A AN 
Sbjct: 435 HGLGYPSMRNDPLLIQNAMHWHGHPLEEARTWVHQACMSPCPTTKHGVQPMRMASATANC 494

Query: 440 AKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIH 499
           AK + YA++ G D  + MQ+GP++        +++++ +     M+WL    +  +N+  
Sbjct: 495 AKMVEYALHNGYDHVVGMQMGPETGDAA-KFHDFEDLFQAWVKQMEWLTSLLVRTVNLGR 553

Query: 500 YMHDKYSYEASLMALHDRDVIRTMA----------CGIAGLSVA--ADSLSAIK---YAK 544
           Y   ++     L  + +R V   +           C +   +     DSL+A+K   +  
Sbjct: 554 YKDPEFFGRPFLSGMSERSVESGLDVVSPVGDRGNCWVTAFTWVENIDSLAAVKKLVFDD 613

Query: 545 VKPIRDEDGLAIDFEIEG----------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHT 594
            K   ++   A+    +G            P++GN+D  VDD+ +        +    H+
Sbjct: 614 KKYTMEQLLTALKANWDGYEEMRLDFVNNAPKWGNDDDYVDDIMLR-----CLRETARHS 668

Query: 595 YRDAIPTQSVLTI-----TSNVVYGKKTGNTPDGRRAGAPFGPG-ANPMHGRDQKGAVAS 648
                P+ +   I     + N+ Y    G  P+GRR G     G  +P  G D+KG  A 
Sbjct: 669 RVMKCPSGNSWPILPENVSGNIHYASIVGALPNGRRCGDALYDGGISPGPGLDKKGPSAV 728

Query: 649 LTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNV 708
           L S  K+              + P  L  +   +      L   Y    A + G  H+  
Sbjct: 729 LKSCGKIDHVSDGRAFLLNQRLSPTQLAGEKGYQ------LWKAYIRTWADL-GLDHVQF 781

Query: 709 NVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFT 757
           N+++ E L  A ++PEKY ++ +RV+GY+  F  ++++ Q ++I RT  
Sbjct: 782 NMVSDETLRAAQKDPEKYSEVIVRVAGYSAHFVDISRKTQDNIIQRTVQ 830


>UniRef50_B0CLU5 Alpha-subunit of naphtylmethylsuccinate synthase n=4 Tax=Bacteria
           RepID=B0CLU5_9DELT
          Length = 828

 Score =  509 bits (1311), Expect = e-142,   Method: Composition-based stats.
 Identities = 140/787 (17%), Positives = 273/787 (34%), Gaps = 98/787 (12%)

Query: 58  VMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIK 117
           + E  K        +     +   +  +   +IN   E IVG   E P   A+ P  G  
Sbjct: 52  LTESYKETRGESEMIRRAKGL-DHVLENYPIFIN-DEEFIVGDAAENPDTLAIFPEMGFF 109

Query: 118 MIEGSCKAYNRELDP---MIKKIFTEYRKT-HNQGVFDVYTP-DILRCRKSGVLTGLPDA 172
                 +      D      ++I   ++           Y   +I       ++   P  
Sbjct: 110 PTIDIVEDPELMDDDIRDEAREIAMFWKPLGLQDKCMPYYDQHEIDIATPWTIVDVPPFI 169

Query: 173 YGRGRIIGDYRRVALYGIDYLMKDKLAQFTS----------------------------L 204
                +   Y  V   G+   +K                                    +
Sbjct: 170 ANYMSVCPAYMSVLEDGLLGRIKSAEENIEKAFVKLRAYPWNGPENMPLMDQIDVWRAMI 229

Query: 205 QADLENGVNLEQTIRLREEIAEQ----------HRALGQMKEMAAKYGYDISGPATNAQE 254
            AD        +  RL + +AE                ++ E++       + PA   ++
Sbjct: 230 IADKAVIKWARRYSRLAKIVAENFDLSDSVQGAEERKNELLEISDICYRMPAEPAKGFKD 289

Query: 255 AIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIER---DLKAGKITEQEAQEMVDHLVM 311
           A+Q  +F YL     +  ++         +  Y +    D  A  +T  EA ++V+   +
Sbjct: 290 AMQSKWFVYLVCHSLERYSSGYAHLEDRLMWPYYKASVIDKTAQPMTRDEAIQLVELERL 349

Query: 312 KLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPN 371
           K+      +   + E   G       +IGG+  +G       +   L     +  +PEP+
Sbjct: 350 KVCERGVAKGRAHREGQPGANDLHIITIGGLDENGNDATNDLTNVILEASLNI-RTPEPS 408

Query: 372 MTILWSEKLPLNFKKFAAK-VSIDTSSLQYENDDLM---------RPDFNNDDYAIACCV 421
           +   +S K+    ++   + ++        ++++            P      +A+  C+
Sbjct: 409 LGFRYSPKINAKTRRLVFENIAAGFGFPSIKHEEKNTRQMLEHYKVPPDEAAHWALVLCM 468

Query: 422 SPMIVG-----KQMQFFGARANLAKTMLYAINGGVDEKL-KMQVGPKSEPIKGDVLNYDE 475
           +P +       K     G    + K    A   G D     +Q GPK+         ++E
Sbjct: 469 APGVSKRRGLQKTRTEGGGLIWIDKCCEIAFYDGFDHSFANIQTGPKTGDAT-KFKTFEE 527

Query: 476 VMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGI-------- 527
           + E  +  +++    +    ++      K+     + +L D  +   +   +        
Sbjct: 528 LFEAFEKQVEFATALHYRNKDVTRRAEIKFIESPFVASLDDACMDDGVGAFVDKTYPNPW 587

Query: 528 ---AGLSVAADSLSAIK---YAKVKPIRDEDGLAIDFEIEG---------EYPQFGNNDP 572
               G   AADSL+A+K   +   K   +E   A+    +G           P++GN+DP
Sbjct: 588 NNTPGEQTAADSLAAVKKLVFDDKKYTMEEVVNAMKANFDGYEEMRKDMLAAPKWGNDDP 647

Query: 573 RVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGP 632
            VD++   + +    K+ +  TY    P  +  T+++      + G  P G+  G     
Sbjct: 648 YVDEIGERVFKMVADKLMEQTTYSGMHPLGNPQTVSTFATRAPRIGALPFGKLHGEVLHD 707

Query: 633 G-ANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMD 691
           G ++P  G D+KG  A L SVA +P+   K G+ +   +  + +  D   +      +  
Sbjct: 708 GGSSPYVGLDKKGPTAVLKSVAHIPYDRYK-GVQFNQRLPVSIMRGDKGFQ------VWS 760

Query: 692 GYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDV 751
            Y      +    H+  NV+  + +L+A + PEK+  L +R++GY+ RF SL K  Q  +
Sbjct: 761 AYMKAWHDLN-IDHVQFNVVETKDMLEAQKEPEKWESLIVRIAGYSARFVSLPKNAQDAI 819

Query: 752 ITRTFTQ 758
           I R   Q
Sbjct: 820 IARNEQQ 826


>UniRef50_B8FMK7 Formate C-acetyltransferase n=1 Tax=Desulfatibacillum alkenivorans
           AK-01 RepID=B8FMK7_DESAA
          Length = 838

 Score =  502 bits (1293), Expect = e-140,   Method: Composition-based stats.
 Identities = 131/685 (19%), Positives = 229/685 (33%), Gaps = 104/685 (15%)

Query: 169 LPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQAD--------------------L 208
                  G ++  Y  V   G   +     ++  +L  +                     
Sbjct: 165 GNAGATSGHLVPGYEDVLKKGWKGVHDYLASRLDALGPENQNSHQANQLKAMMTAATMPR 224

Query: 209 ENGVNLEQTIRLREEIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVK 268
           +        IR  E+         ++  MAA   +    P  +  EAIQ  +  ++  + 
Sbjct: 225 DLAARYASLIRDMEQKESDPERKEELARMAANLDHTPWNPPRDFWEAIQALWLTHMLVLS 284

Query: 269 SQN--GAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMV--RFLRTPEY 324
            +N  G  +SFGR   +L  Y E  +  G +  +  +E++    +         +RT   
Sbjct: 285 DENYPGPGVSFGRVDQYLLPYWEASMAQG-MDREWGKEILKCFWIHANTAYDAMIRTGAN 343

Query: 325 DELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNF 384
             + +G       ++ GMG DG  L    ++ FL  +  M P  EP   +      P   
Sbjct: 344 GGITAGY--GQLITLSGMGPDGTDLTNDLTYVFLEVIDEMSPILEPKPNVRLHANTPEEL 401

Query: 385 KKFAAKVSIDT-SSLQYEN-DD------------LMRPDFNND----DYAIACCVSPMIV 426
                 +  ++  +    N D+              R D  N+     YA   C+   +V
Sbjct: 402 YDHIIDMIAESQGAPFLLNFDERSMAGMMREAEKAGRQDLINESNVWQYAPVGCLENTMV 461

Query: 427 GKQM-QFFGARANLAKTMLYAINGG------VDEKLKMQV-----GPKSEPIKGDVLNYD 474
           G           NL K + +A+ GG       D  +  +      G  +     +   ++
Sbjct: 462 GNDRSGTVDINLNLLKAVEFALTGGADLLPYKDTIMGKEYPIDASGIPTGDPT-EFTVFE 520

Query: 475 EVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAG----- 529
           E           + K+ +        +   Y     L  L      +       G     
Sbjct: 521 EFFAAFAKQTRHIIKKAMDLYETSESVRAAYHPTPYLSCLVKGCAEKGKDVTQGGAELSF 580

Query: 530 -------LSVAADSLSAIKYAKVKP---IRDEDGLAIDFEIEGE----------YPQFGN 569
                   +   DSL A+KY           E   A+    EG            P++G 
Sbjct: 581 VTIEAVTFATTVDSLLAVKYLVFDEKICTMAELIQALKDNWEGHDILMARAKFKAPKYGR 640

Query: 570 NDPRVDDLAVDLVERFMKKIQKLHT-YRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGA 628
           +D   D++A  +++ + ++  K  T          +L+    V  G     +PDGR  G 
Sbjct: 641 DDDEADEMARKVMDLWTEETWKHKTQSTGRQARPGMLSWNYWVGDGYILHASPDGRPKGQ 700

Query: 629 PFGPGANPMHGRDQKGAVASLTSVAKL---------PFAYA----KDGISYTFSIVPNAL 675
                  P +G D  G  ++  SV K           F        +G S+T +  P+ L
Sbjct: 701 FLSNAICPTNGADINGPTSNANSVGKALGGRKPGKGDFGDYLNSLPNGASHTITFNPSIL 760

Query: 676 GKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSG 735
                + K      + GY  +     GG  L +N+++ +ML DA +NP  Y  L +R++G
Sbjct: 761 ADP--LHKEKFKAYLKGYVQN-----GGTALQINMLDADMLKDAQKNPADYRHLLVRITG 813

Query: 736 YAVRFNSLTKEQQQDVITRTFTQSM 760
           Y   F S+ KE Q +VI R   + +
Sbjct: 814 YNAYFTSIGKELQDEVIARLSHEGL 838


>UniRef50_UPI00016BFDA6 pyruvate formate-lyase n=1 Tax=Epulopiscium sp. 'N.t. morphotype B'
           RepID=UPI00016BFDA6
          Length = 766

 Score =  496 bits (1277), Expect = e-138,   Method: Composition-based stats.
 Identities = 162/801 (20%), Positives = 282/801 (35%), Gaps = 120/801 (14%)

Query: 41  ESFLAGATEA--TTTLWDKVMEGVKLENRTHAPVDFD------TAVASTITSHDAGYINK 92
           +S L    EA    ++ +  ME ++    T      D            I  + +  +  
Sbjct: 2   DSILEKKIEALFGRSVKETFMERIQYTFETEFMFANDSFAVKYGKTLYHILDNISVVLED 61

Query: 93  QLEKIVGLQTEAPLKRALIPFGGIKMIEGSCKAYNRELDPMIKKIFTEYRKTHNQGVFDV 152
            + KIVG           IP      +E   K Y+R  D  ++  F          V   
Sbjct: 62  DM-KIVGCVKVR------IPED--SEVEEILKVYHRWWDMSVEDRFK--------KVAFY 104

Query: 153 YTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLENG- 211
           YT   L+CR              G +  DY  +   G D ++K    + T    + +   
Sbjct: 105 YTNGWLKCRPY-------WFASFGHLGIDYEDLVFNGYDSIIKRAQTRLTKSCNEKQQEF 157

Query: 212 -----VNLEQTIRLREEIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAA 266
                ++++      E  A    A G++ ++A         PA   ++A+Q  +   L  
Sbjct: 158 LNGIIISIQALSNFYERYATAAVAAGKI-DLADDLKTIAHQPAKTFKQALQHIWLNTLVL 216

Query: 267 VKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDE 326
            K      ++F R   +L    ++D+KAG +T +EA  +V+    +   +        +E
Sbjct: 217 QKVSGCGVLNFSRLDKYLQPLYDQDIKAGILTREEALNLVEEFYFRNNEMMAQTDHMSEE 276

Query: 327 LFSGDPIW-------ATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEK 379
                             ++GG+  DG + V + S+  L     M     P + + + E 
Sbjct: 277 TTGTKDTLELAFDDPNYLTLGGINADGTSAVCELSYIMLEAANEM-RLRNPFIVVRYHEG 335

Query: 380 LPLNFKKFAAKVSIDTSSLQYENDDLMRPDF--------NNDDYAIACCVSPMIVGKQMQ 431
           +  +F K  AK   + +++   ND+ M P             DY    C  P I   +  
Sbjct: 336 IAEDFWKLCAKAMRNNATVVVYNDETMIPALKYHNISAPEVYDYGFWGCNDPNIAAYEGG 395

Query: 432 FFGARANLAKTMLYAINGG--------------------VDEKLKMQVGPKSE---PIKG 468
                 N+AK +  A++ G                     D  + + +GP          
Sbjct: 396 LRQLWMNMAKPLELALHQGDYPLEPKKEEDVAKECAWSIEDRMMGIMIGPYYGIKTKPAN 455

Query: 469 DVLNYDEVMERMDHFMDWLAKQYITALNI--------------IHYMHDKYSYEASLMAL 514
           ++ + +E ++  +   D L  ++                    I     K + E ++   
Sbjct: 456 EINSMEEFLKIFEIQFDHLISEFRKGFEADFIIEQHETVGKMRIEDCFLKGTIENAVTWT 515

Query: 515 HDRDVIRTMACGIAGLSVAADSLSAIKYAKVK---PIRDEDGLAIDFE----------IE 561
                   +     GL+   ++L  I+           +E    +              +
Sbjct: 516 EGGTKYHKIVAQGCGLATVINALYIIEKVVFDEKLLTLEELATMMRNNYEGNEHWRLKFK 575

Query: 562 GEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSN----VVYGKKT 617
            +YP+FGN+   VD  A  + + FM+ I K                 S      + G+  
Sbjct: 576 NKYPKFGNDIDEVDKYAQIITDIFMRIIAKH---NGPEYLYQFWPTYSTDRAFTIMGEHV 632

Query: 618 GNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGK 677
           G TPDGR A  P     +P  G D +G  A L S++K+PF     G      + P     
Sbjct: 633 GATPDGRLAREPISENQSPADGSDLEGVTAMLNSLSKVPFNRITGG-PLNLRLHPTVAAG 691

Query: 678 DDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYA 737
           D  +    +A L+  Y       +GG  L +NV++ E L  A ENP+KY  L +RV+GY+
Sbjct: 692 DKGI--DTVAALLKTYMQ-----KGGMQLQLNVIDAETLKLAQENPDKYRSLCVRVTGYS 744

Query: 738 VRFNSLTKEQQQDVITRTFTQ 758
             F  + K+ Q ++I RT  Q
Sbjct: 745 AFFVEMGKKAQDELIHRTQHQ 765


>UniRef50_Q38HX4 4-hydroxyphenylacetate decarboxylase glycyl radical subunit n=3
           Tax=Clostridiales RepID=Q38HX4_9CLOT
          Length = 897

 Score =  495 bits (1275), Expect = e-138,   Method: Composition-based stats.
 Identities = 130/743 (17%), Positives = 246/743 (33%), Gaps = 122/743 (16%)

Query: 127 NRELDPMIKKIFTEYRKTHNQGVFDVYT------PDILRCRKSGVLTGLPDAYGRGRIIG 180
            +E  P++ K    +     + + + Y+             +S +      A  +GR + 
Sbjct: 167 RKEEIPVLVKTSKPWEGISVEELSNKYSKMTPGYDQFKNIMESVICMFDSFAIPQGREVI 226

Query: 181 DYRRVALYGIDYLMKDKLAQFTSL----------------------QADLENGVNLEQTI 218
           +Y     YG D ++K    +   +                      +         E   
Sbjct: 227 NYYMPLQYGFDGIIKLCDEKIAEVMGEAGDDGDFGMSRGYYYAAMKEITKGLSAWCENYS 286

Query: 219 RLREEIA---EQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAM 275
           +  + +A            +++    G        N  EAIQ T   +   V     + +
Sbjct: 287 KRAKYLASIETDSEIKANYEKIEEVMGNIAHKKPANFWEAIQMTLCCHFGVVNEDPQSGL 346

Query: 276 SFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWA 335
           S GR    L  + E+D++ G +T++E  E+++   +K+  +    +            + 
Sbjct: 347 SIGRLGQVLQPFYEKDVEDGIMTDEEVIELLELYRIKITCIECFASAGVSGGVLSGNTFN 406

Query: 336 TESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKV-SID 394
             S+GG   DG + VT   +  +        +P+P +++L+ EK P +F   AA    + 
Sbjct: 407 NLSLGGQNYDGLSAVTPLEYLIVEAGMR-NQTPQPTLSVLYDEKTPEDFLMKAASCTKLG 465

Query: 395 TSSLQYENDDLMRPDF------------NNDDYAIACCVS---------------PMIVG 427
                + N+                   +   + +  C+                 MI G
Sbjct: 466 LGYPAWMNNQTGMNFMMRNYGPEGMDLHDARAWCLGGCLESAPGCFLPLEYNGKVTMIPG 525

Query: 428 KQMQFFGA---RANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFM 484
                 G       + K +   +  G+D++   QV P   P    + +Y+ ++ +   +M
Sbjct: 526 GASPTCGTGVHFIGMPKVLELVLTNGLDKRTGKQVYP---PHNKKLDSYETMVNQWKEYM 582

Query: 485 DWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGI-------------AGLS 531
           +          NI   +  KY+  A    L      +    G               G  
Sbjct: 583 ELTTDVVNRCNNIQMDIWRKYNMPAVNSLLKPDCFKKGKHIGTMGARYNSCINFESCGTI 642

Query: 532 VAADSLSAIKYAKVKPIR-----DEDGLAIDFEIEG------------------------ 562
              +SLS+IK       +       D +  +F  +                         
Sbjct: 643 TFVNSLSSIKKNVFDDSKFTIEEMTDAMLNNFGFKTAYETEVFSPDFRESTDKSTKYEKI 702

Query: 563 -----EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKT 617
                  P++GN D   D++             K  +Y         ++++++   G  T
Sbjct: 703 FAACVNAPKYGNADKYADEIFKAYHYYIYDMTHKFRSYYGKPLYLCQISVSTHGPQGFVT 762

Query: 618 GNTPDGRRAGAPFGPG-ANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALG 676
             T DGR AG  +  G  +   G D+ G  A   S      +  ++       + P A+ 
Sbjct: 763 LATADGRLAGTTYSDGSVSAAAGTDKNGIYAIFESATVYDHSMHQN-AQMNLKLHPTAVK 821

Query: 677 KDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGY 736
             +  RK  L  L+  Y       +GG H+  NV++ + L DA   PEKY +L +RV+G+
Sbjct: 822 GINGTRK--LLDLVRAYMR-----KGGFHVQFNVVDSKTLRDAQLTPEKYRELMVRVAGF 874

Query: 737 AVRFNSLTKEQQQDVITRTFTQS 759
              +  + K  Q +VI RT    
Sbjct: 875 TQYWCEIGKPIQDEVIYRTEYDK 897


>UniRef50_B2V300 4-hydroxyphenylacetate decarboxylase, catalytic subunit n=12
           Tax=Bacteria RepID=B2V300_CLOBA
          Length = 905

 Score =  492 bits (1268), Expect = e-137,   Method: Composition-based stats.
 Identities = 135/746 (18%), Positives = 255/746 (34%), Gaps = 121/746 (16%)

Query: 119 IEGSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRI 178
           I    K     +D  +  +  +Y +              L C              +GR 
Sbjct: 177 IPVLVKLAKEWVDRSVDDLGHKYEQMVPDYEIKENIMKSLICM-----FDSGFTLPQGRE 231

Query: 179 IGDYRRVALYGIDYLMK---------------------DKLAQFTSLQADLENG----VN 213
           + +Y     YG D L+                      D+L  + +++  LE      +N
Sbjct: 232 VVNYYYPLQYGFDGLIDMAVECKKKVAGNADGDGLVGMDRLYFYEAVKITLEGIQNWILN 291

Query: 214 LEQTIRLREEIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGA 273
            E+  R    I +      +  E+A    +         +EA+Q TY  ++A +     +
Sbjct: 292 YEKHARDLALIEKNQSQKEEYIEIADCLNWIAHKQPRTFREALQLTYIIHIAVINEDAIS 351

Query: 274 AMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPI 333
            +S GR    L  + ++D++ G+ITE+E  E+++   +K   +    +            
Sbjct: 352 GLSPGRVGQVLYPWFKQDIENGRITEKEVLELLELHRVKFTCIDCFASTGVVGGVLSGNT 411

Query: 334 WATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKV-S 392
           +   ++GG+  DG +   +  +  +    T   +P+P ++  + EKLP +F     +   
Sbjct: 412 FNNLTLGGLKKDGSSAANRLEYLIVEAGITCA-TPQPTLSCFYDEKLPEDFLLKCIECDK 470

Query: 393 IDTSSLQYENDDLMRPDFN------------NDDYAIACCVSPM---------------I 425
             +    + N+                        AI  C+                  I
Sbjct: 471 TGSGYPAWMNNRGAIEFMMNQYGDEGMTIEEARSVAIGGCLETSPCTWKELTLNGEKFDI 530

Query: 426 VGKQMQFFGARANL---AKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDH 482
            G   Q      +     K +   +  G D +  +QV P+       +  +++V+ +   
Sbjct: 531 PGGAGQPTSVGVHFIANPKVLELVLTNGKDYRTNLQVYPEH---NRKLETFEDVVNQFKE 587

Query: 483 FMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACG-------------IAG 529
           + +          NI H +  K +       L    +      G               G
Sbjct: 588 YYELTCDVLAKTNNIQHDIWRKKNMSIVNSLLKPNCLDVGKHIGNLGYRFNATYNVESCG 647

Query: 530 LSVAADSLSAIK---YAKVKPIRDEDGLAIDFEI-------------------------- 560
                +SL+++K   Y   K   DE   AI                              
Sbjct: 648 TINTINSLASLKKLVYDDKKYTLDEMREAILNNFGFKTAEEIGSYSLADQEKAGISSKYD 707

Query: 561 --EGEY---PQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGK 615
              G+    P++GN+DP VD +  D  + F        +          ++++++   G 
Sbjct: 708 DIYGDCLLAPKYGNDDPYVDSILKDYEDWFCDVCHNYESLYGKKMYACQISVSTHGAQGA 767

Query: 616 KTGNTPDGRRAGAPFGPG-ANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNA 674
            T  T DGR AG  +  G  +   G D+ G  A  TS      + +++       I P+A
Sbjct: 768 ATLATTDGRLAGTTYADGSMSAYPGTDKNGPYALFTSATVWDHSKSQN-SQMNLKIHPSA 826

Query: 675 LGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVS 734
           +   +  +K  L  L   Y       +GG H+  NV++ ++L +A   PE Y  L +RV+
Sbjct: 827 IKGIEGSKK--LLDLTRSYMR-----KGGYHIQYNVVDSKVLKEAQVKPESYRDLMVRVA 879

Query: 735 GYAVRFNSLTKEQQQDVITRTFTQSM 760
           G+   +  + K  Q +VI+RT  + +
Sbjct: 880 GFTQYWCEIGKPIQDEVISRTEYEGV 905


>UniRef50_B0MIH0 Putative uncharacterized protein n=1 Tax=Anaerostipes caccae DSM
           14662 RepID=B0MIH0_9FIRM
          Length = 803

 Score =  487 bits (1253), Expect = e-136,   Method: Composition-based stats.
 Identities = 140/677 (20%), Positives = 250/677 (36%), Gaps = 94/677 (13%)

Query: 135 KKIFTEYRKTHNQGVFDV-YTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYL 193
           K +         +  F + Y  +  +      L      +    +  +Y R    G+  +
Sbjct: 164 KDLEPYEIGRELERAFKIPYAAEDKK------LYNELPWFVGNHLNLNYGRALQKGLLQM 217

Query: 194 MKDKLAQF------TSLQADLENGVNLEQTIRLREEIAEQ-----------HRALGQMKE 236
             + +++          +      + ++  IR  +  A++                ++K 
Sbjct: 218 KDEIISRLGSSSDPEKSEYYEAARIAVDAVIRFIKRYADELDLHSQNTNVTEERSRELKR 277

Query: 237 MAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGK 296
           MA         PA +  EA+Q T+  ++ A   Q G+A+SFGR   +L  Y ++D + G+
Sbjct: 278 MADICRKISEKPAKSFYEAVQLTWMLHIIANI-QGGSALSFGRLDQYLYPYFKKDTEEGR 336

Query: 297 ITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFR 356
           IT  EA+E+V  L +K+   +                  + ++GG+  DG+    + +  
Sbjct: 337 ITYSEAKELVGCLWLKVNEPKMR-------------TVQSVTLGGITPDGKDAANELTRI 383

Query: 357 FLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAK-VSIDTSSLQYENDDLMR-------- 407
            L T    G  P PN+ +  +   P    + A + +          ND++          
Sbjct: 384 CLQTAKDAG-MPYPNVGLRVNRLNPDWIYEEALETIKAGCGQPMLLNDEIWITNMKKLGY 442

Query: 408 PDFNNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIK 467
           P+   +DY    CV  MI GKQ   +G    +A  +L             +V  K    +
Sbjct: 443 PEDQANDYYNMGCVEIMIPGKQ-PNWGVTEAIAFPVLI-----------EEVMRKWGAGE 490

Query: 468 GDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMA--- 524
             + ++DE M+     MD   +              +  Y+     L D  +        
Sbjct: 491 IKIRSFDEFMDAYLQEMDIAIEADRQEALQKKANMTERCYDPFSSVLIDGCLEHGKDMLQ 550

Query: 525 ----------CGIAGLSVAADSLSAIKYAKVKP---IRDEDGLAIDFEIEG--------- 562
                         G+  AADSL A+K           ++   A++ + EG         
Sbjct: 551 GGSECPVHWSVYAYGIGTAADSLCAVKKFVFDDQKVTLEQMKDALEADFEGYEELRAMLD 610

Query: 563 -EYPQFGNNDPRVDDLAVDLVERFMKKIQKL-HTYRDAIPTQSVLTITSNVVYGKKTGNT 620
              P +GN    VD +A  ++  F K + +L H         ++     ++ +G+  G T
Sbjct: 611 RMTPAYGNGLEEVDSIADKVLTHFSKSVFELNHNSEKDKYVSTLFGYFFHIYHGEIVGAT 670

Query: 621 PDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDE 680
           P+GR  G PF     P  G+D KG    L SV +L   Y   G +  + + P  L ++  
Sbjct: 671 PNGRHKGEPFSDSMGPGQGKDVKGPTRLLHSVIRLNDDYITGGYALNYKLNPAFLNEEKG 730

Query: 681 VRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRF 740
             +     L+  Y  +      G  + V   N + + DA  +PEK+  L +RV GY   F
Sbjct: 731 --RQAAISLLKTYIENR-----GPQIQVYTTNLDDIKDAQVHPEKHRDLIVRVGGYCEFF 783

Query: 741 NSLTKEQQQDVITRTFT 757
            +L +  Q ++I RT  
Sbjct: 784 VNLDRVLQNEIIARTMY 800


>UniRef50_Q39VF1 Formate C-acetyltransferase glycine radical:Pyruvate formate-lyase,
           PFL n=87 Tax=Bacteria RepID=Q39VF1_GEOMG
          Length = 862

 Score =  483 bits (1243), Expect = e-134,   Method: Composition-based stats.
 Identities = 134/787 (17%), Positives = 258/787 (32%), Gaps = 99/787 (12%)

Query: 57  KVMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGI 116
            + E  K        +     +A+ +    +  + +Q E I+G   E P    L P    
Sbjct: 75  FITEAHKASAGQPEVIRRALGLANILNK--STLVLQQDEFIIGYHAEDPEMFPLYPELAY 132

Query: 117 KMIEG-SCKAYNRELDPMIKKIFTEYRK-THNQGVFDVYT-PDILRCRKSGVLTGLPDAY 173
             ++      Y+ +      +I   ++K +        +T  ++L+  +   +     A 
Sbjct: 133 MAVQDYLMSDYSPQPKEEAAEINEYWKKYSMQAKGERYFTQEELLQMYQVSTMEAPGFAT 192

Query: 174 GRGRIIGDYRRVALYGI-----------DYLMKD----------------KLAQFTSLQA 206
           G   I   Y  V   G+           ++  ++                K+  + ++  
Sbjct: 193 GYNSISPPYETVLQDGLLKRIEMAHEKIEHAKREMQKIPWDATTGLDWIAKIDVWKAMII 252

Query: 207 DLENGV-NLEQTIRLREEIAEQHR----ALGQMKEMAAKYGYDISGPATNAQEAIQWTYF 261
             E  +    +  RL + +AE          ++ E+A       + P    ++A Q  ++
Sbjct: 253 ADEAVINWARRHARLAKIVAENFETNPARKEELLEIAEISHRVPAEPCKGLKDAFQAKWY 312

Query: 262 GYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGK---ITEQEAQEMVDHLVMKLRMVRF 318
            YL        A+    +    L+ Y    +K      +T  +  EMV+   +K+     
Sbjct: 313 TYLICHAIDRYASGYAQKEDEMLEPYYNISVKEKSFQPMTHTDVVEMVEMERLKISEHGA 372

Query: 319 LRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSE 378
            ++  Y E+F G       +IGG         +  +   L     +  + EP++   W  
Sbjct: 373 GKSRAYREIFPGSNDLFILTIGGTKPGYVDACSDMTDAILEGARNI-RTTEPSIVFRWHP 431

Query: 379 KLPLNFKKFAAKVSI-DTSSLQYENDDLMRPDF----------------NNDDYAIACCV 421
                 K+   +           ++D +                         + +  C+
Sbjct: 432 VGREKTKRLVFECIRDGLGYPSIKHDVIGTEQLKYYSQFSKNNNGATDDEAHYWGLVLCM 491

Query: 422 SPMIVG-----KQMQFFGARANLAKTMLYAINGGVD-EKLKMQVGPKSEPIKGDVLNYDE 475
           SP + G     K     G     AK M   +  G D     MQ+GP +         +++
Sbjct: 492 SPGVCGRRKTHKTRSEGGGSIFPAKMMEIVLADGFDWSYSGMQLGPHTGDPTT-FKTFEQ 550

Query: 476 VMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMAC-----GIAGL 530
           + E       +   + I A +I+ Y   K+     + ++ D  +   +          G 
Sbjct: 551 LWEAFRSQYAYATSKVIRAKDIMRYYESKFLQMPFVSSIDDGCMELGIDSMELSEQPNGW 610

Query: 531 ------SVAADSLSAIK---YAKVKPIRDEDGLAIDFEIEG---------EYPQFGNNDP 572
                  VAA+SL AIK   Y + K    +   A+     G           P++GN+D 
Sbjct: 611 HNPITTVVAANSLVAIKKLIYDEKKYTMAQLVTALRANWHGYEDMRQDFLNAPKWGNDDE 670

Query: 573 RVDDLAVDLVERFM-KKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTP-DGRRAGAPF 630
             D +     E  +  ++ K+  Y           +   +  G +TG TP       A  
Sbjct: 671 YADTIIKKFYEDIIGGEMAKITNYSGGPVLPVGQAVGLYMEIGSRTGPTPDGRFGGDAGD 730

Query: 631 GPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLM 690
             G +P  G D+KG  A L SV+K+      +       +    +             + 
Sbjct: 731 DGGISPYMGTDKKGPTAVLKSVSKVQKNQKAN--LLNQRLSVPIMRSVHGF------TIW 782

Query: 691 DGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQD 750
             Y      +    H+  N ++   +  A + PEK+  L +RVSG++ RF  +    Q  
Sbjct: 783 KSYMDAWEKLN-IDHVQFNCVSTAEMKAAQKEPEKHQDLIVRVSGFSARFVDIPTYGQNT 841

Query: 751 VITRTFT 757
           +I R   
Sbjct: 842 IIARNEQ 848


>UniRef50_C5EHI0 Pyruvate formate-lyase n=8 Tax=Bacteria RepID=C5EHI0_9FIRM
          Length = 703

 Score =  477 bits (1228), Expect = e-133,   Method: Composition-based stats.
 Identities = 140/733 (19%), Positives = 266/733 (36%), Gaps = 109/733 (14%)

Query: 89  YINKQLEKIVGLQTEAPLKRAL-IPFGGIKMIEGSCKAYNRELDPMIKKIFTEYRKTHNQ 147
           Y+ ++++K    + ++P   A      G+  +E S K     L+     +F + R    +
Sbjct: 12  YVVQKIQKRFRREKDSPYALAEDFHEQGLSGLERSVKRLTYMLEQERPVVFKDERIGLIR 71

Query: 148 GV---FDVYTP-DILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKL----- 198
            V   ++++T  +    +K   +           I   Y  +   G D + ++       
Sbjct: 72  TVPVNYEIFTEDEWKEIKKDHYIHEQGKVC---NINPRYGLLLDRGFDAVRREIERQKGM 128

Query: 199 --------------------AQFTSLQADLENGVNLEQTIRLREEIAEQHRALGQMKEMA 238
                                    L A  E    +E       E A++        EMA
Sbjct: 129 YALDGQGGPSAQGTGHGFESESLRYLNALTETLDAIEAFAGRYGEEAQRAGNP----EMA 184

Query: 239 AKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKIT 298
             +G+          EA+Q+    +     S N    +FGR   ++  Y + D+++G++T
Sbjct: 185 RVFGHIPKQRPGTFMEALQFLRLLHYCLWCSFNYH-NTFGRFDQYMYPYYKADMESGRLT 243

Query: 299 EQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFL 358
           ++EA E+++   +         +  Y  +  GD    +  +GG+  DG     + S   L
Sbjct: 244 KEEALELLEEFFISCNKD----SDLYPGMQQGDN-GQSMVLGGLNPDGSDSFNELSDLCL 298

Query: 359 NTLYTMGPSPEPNMTILWSEKLP-LNFKKFAAKVSIDTSSLQYENDDLMRPDF------- 410
                +    +P + +  ++  P   +++            QY NDD++ P         
Sbjct: 299 QASLEL-KLIDPKINLRVNKDTPLARYERGTQLTRQGLGFPQYANDDVVIPCLRHWGYAE 357

Query: 411 -NNDDYAIACCVSPMIVGKQMQFFGAR-ANLAKTMLYAINGGVDEKLKMQVGPKSEPIKG 468
            +  DY +A C   +I G  M        + A  +L  +    D                
Sbjct: 358 KDAYDYVVAACWEFIIPGTGMDIPNVNGLSFAAVVLDVL----DSLPG------------ 401

Query: 469 DVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYS-YEASLMALHDRDVIR------ 521
               ++  M+++   +      +  A  +   +H+ Y      +  + D  V R      
Sbjct: 402 -CGTFEAFMDKVKGEI------FRMAGELCDSVHNVYMEPAPLMSLMMDGCVERARDISK 454

Query: 522 -----TMACGIAGLSVAADSLSAIKYAKVKP---IRDEDGLAIDFEIEG----------E 563
                       GLS A DSL+AI+    +      +E    +D + +G          +
Sbjct: 455 GNLYNNYGFHGTGLSTAVDSLAAIRKYVYEDRMFTAEELLKMLDADFKGYEDIQNMLRYQ 514

Query: 564 YPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDG 623
            P+ GN+D RVD+LA  L++ F   ++  +     I      +    V + +    TPDG
Sbjct: 515 SPKMGNDDDRVDELATRLLDWFADSLEGRNNDMGGIFRAGTGSAMYYVWHSRNQHPTPDG 574

Query: 624 RRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRK 683
           R  G       +P      +G V+ + S +K       +G   T  +  +    +D +RK
Sbjct: 575 RNEGEELACNYSPSLFTRLEGPVSIIKSFSKPHLERVANGGPLTIELHDSMFRNEDSIRK 634

Query: 684 TNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSL 743
             +A  +  +        GG  + +N +NRE +LDA E+PE +  L +RV G++  F  L
Sbjct: 635 --VAVFVKSFMDM-----GGHQMQINAVNRETMLDAKEHPENHKNLIVRVWGWSGYFVEL 687

Query: 744 TKEQQQDVITRTF 756
            +  Q  +I R  
Sbjct: 688 DEVYQNQIIKRME 700


>UniRef50_A9KN53 Pyruvate formate-lyase n=21 Tax=Bacteria RepID=A9KN53_CLOPH
          Length = 867

 Score =  468 bits (1204), Expect = e-130,   Method: Composition-based stats.
 Identities = 103/563 (18%), Positives = 196/563 (34%), Gaps = 64/563 (11%)

Query: 56  DKVMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGG 115
             + E  +        +   +     I  +    + ++ E IVG  T A       P   
Sbjct: 35  VLITESYQQTEGEP-IISRRSKAFEHIVKN-LPVVIRENELIVGSATVAERGCQTFPEFS 92

Query: 116 IKM-IEGSCKAYNRELDPMI---------KKIFTEYRKTHNQGVFDVYT-PDILRCRKSG 164
               I        R  DP           +K+ + ++      + D Y  P+     +  
Sbjct: 93  FDWLIAELDTVATRTADPFYISEEAKKELRKVHSYWKGKTTSELADYYMAPETKLAMEHN 152

Query: 165 VLTGLPDAY-GRGRIIGDYRRVALYGIDYLMKDKLAQFTSL------------------Q 205
           V T     Y G G I   Y +V   G + +  + L++   L                  +
Sbjct: 153 VFTPGNYFYNGVGHITVQYDKVIAIGYEGIKDEVLSRKKELHLGDADYASRLTFYDAVIR 212

Query: 206 ADLENGVNLEQTIRLREEIA---EQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFG 262
           +     +  ++     + +A   +  +   ++  +++      +  A    EA Q  +F 
Sbjct: 213 SCDSAILYAKRYAAEAKRLALSCQDEKRRQELLMISSNCERVPAKGANTFYEACQAFWFV 272

Query: 263 YLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTP 322
            L      +G ++S GR   +L  Y + D +AG+IT ++AQE++D + +KL  +   R  
Sbjct: 273 QLLLQIEASGHSISPGRFDQYLYSYYKADREAGRITGEQAQEIIDCIFVKLNDINKCRDA 332

Query: 323 EYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPL 382
              E F+G  ++    +GG   +GR    + SF  L         P+P+++I      P 
Sbjct: 333 ASAEGFAGYGMFQNMIVGGQDSNGRDATNELSFMILEASIH-TMLPQPSLSIRVWNGSPH 391

Query: 383 NFKKFAAKVSI-DTSSLQYENDDLMRPDFN--------NDDYAIACCVSPMIVGKQMQFF 433
           +    AA+V+        Y ND+++ P             +Y I  CV P + GK   + 
Sbjct: 392 DLLIKAAEVTRTGIGLPAYYNDEVIIPAMMNKGATLEEARNYNIIGCVEPQVPGKTDGWH 451

Query: 434 G-ARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYI 492
             A  N+ + +    + G +      VG  +  ++     ++   +     M++     +
Sbjct: 452 DAAFFNMCRPLEMVFSSGYEN--GKLVGAPTGSVEN-FTTFEAFYDAYKTQMEYFISLLV 508

Query: 493 TALNIIHYMHDKYSYEASLMALHDRDVIRTMAC------------GIAGLSVAADSLSAI 540
            A N I   H K        ++ +  + R +                 G++   DSL AI
Sbjct: 509 NADNSIDIAHAKLCPLPFESSMVEDCIGRGLCVQEGGAKYNFTGPQGFGIANMTDSLYAI 568

Query: 541 KYAKV---KPIRDEDGLAIDFEI 560
           K       K    E   A+    
Sbjct: 569 KKLVYEEGKVSITELKEALLHNF 591



 Score =  256 bits (654), Expect = 3e-66,   Method: Composition-based stats.
 Identities = 67/194 (34%), Positives = 103/194 (53%), Gaps = 7/194 (3%)

Query: 564 YPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDG 623
            P++GN+   +D+ A ++   + K +QK    R  +    +  +++NV  G++TG TPDG
Sbjct: 679 LPKYGNDILEIDEFAREIAYTYTKPLQKYKNPRGGVFQAGLYPVSANVPLGEQTGATPDG 738

Query: 624 RRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRK 683
           R A  P   G  P  GRD KG  A+  SVA+L    A +G  Y     P+AL     + K
Sbjct: 739 RLANTPIADGVGPAPGRDTKGPTAAANSVARLDHMDATNGTLYNQKFHPSALQGRGGLEK 798

Query: 684 TNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSL 743
                L+  +F      + G H+  NV++RE LLDA ++PE Y  L +RV+GY+  F +L
Sbjct: 799 --FVALIRAFFD-----QKGMHVQFNVVSRETLLDAQKHPENYKHLVVRVAGYSALFTTL 851

Query: 744 TKEQQQDVITRTFT 757
           ++  Q D+I RT  
Sbjct: 852 SRSLQDDIINRTTQ 865


>UniRef50_D1ANR4 Formate C-acetyltransferase n=1 Tax=Sebaldella termitidis ATCC
           33386 RepID=D1ANR4_SEBTE
          Length = 768

 Score =  467 bits (1201), Expect = e-130,   Method: Composition-based stats.
 Identities = 147/772 (19%), Positives = 277/772 (35%), Gaps = 89/772 (11%)

Query: 47  ATEATTTLWDKVMEGVKLENRTHAPVDFDTAVASTITSHDAGYI--NKQLEKIVGLQTEA 104
             E +T     +ME     ++    +  +    + +           ++ + I G     
Sbjct: 27  PCEKSTAEQLDIMEEYTSVHKASLHLSKEKREINCLNVIFPRLFRNIEEDDLIAGRLDFL 86

Query: 105 PLK-RALIPFGGIKMIEGSCKAYN-------RELDPMIKKIFTEYRKTHNQGVF-DVYTP 155
           P+   ++   GG+       K           E    + KI   + +   + ++      
Sbjct: 87  PVGFGSVTSVGGVGHYCVFDKLQKFQSELVSEEDKKRVDKIGKYWEEHDVKALYCKDVLT 146

Query: 156 DILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDY---LMKDKL---AQFTSLQADLE 209
           +    R       L        ++ DY ++   GID    ++KDKL   A+   L+  LE
Sbjct: 147 EDTIGRFIDCNYPLMATARLSGMMLDYPKLLDNGIDGLKNIIKDKLNKSAENEFLKIALE 206

Query: 210 NGVNLEQTIRLREEI------AEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGY 263
                E+T+    ++            L ++  +        +       +A+Q  +   
Sbjct: 207 TLDLYEKTVDYERKLIAKAMKNAGEERLKELLLIDESLSAIRNNKPKTFHQALQMFWLYA 266

Query: 264 LAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPE 323
           L          +++GR   +L  Y++ DL+ G ITE++A   +  L     ++   RT  
Sbjct: 267 LL------AGCINYGRLDDYLGPYLKHDLETGLITEEDAYRYLKSLW---TLIENRRTTV 317

Query: 324 YDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLN 383
              + +G         G   ++   +    +   L          EP  T+  +++ P +
Sbjct: 318 NGRIITGG-------YGRKNIEAADIF---TRIALKVTKDC-KYVEPQFTLRITKETPQD 366

Query: 384 FKKFAAKVS-IDTSSLQYENDDLMRPDFN---------NDDYAIACCVSPMIVGKQMQFF 433
               A        +     ND++  P             + Y    C   +I G+ +   
Sbjct: 367 IMDMAYDCIGEGVTYPTLYNDEINIPAVMYSMRVDRETAEQYVPFGCGEFVIQGQSVGTP 426

Query: 434 GARANLAKTMLYAINGGVDEKLKMQV-GPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYI 492
               NL K +   +N G+D     +  G        +  ++DE+  +    +D+      
Sbjct: 427 NILINLLKILNITLNKGIDPMDGKKKSGNIIMKDPDEYRSFDELYSKYKELLDYYLDLSA 486

Query: 493 TALNIIHYMHDKYSYEASLMALHDRDVIRTMAC------------GIAGLSVAADSLSAI 540
            A    + + ++         L +  + R  +                G   ++D+L AI
Sbjct: 487 DAQYHSYEVMNREVSFMFASILTNDCISRGKSILDGGVRYLGGTNETYGNINSSDALYAI 546

Query: 541 K---YAKVKPIRDEDGLAIDFEIEG---------EYPQFGNNDPRVDDLAVDLVERFMKK 588
           K   + + K    E   A     +G            ++GN+    D+LA DL E   K 
Sbjct: 547 KTLVFDQKKYTLKELNEAAHHNFKGYEKIREELWNCGKYGNDIEEADELANDLYEFVAKG 606

Query: 589 IQKLHTYRDAIPTQSVLTIT-SNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVA 647
            +     +       V++   +N  +G+KT  + DGR +G    P  NP  G D+ G  A
Sbjct: 607 NRDRGLKKGMDYFLIVISNNQTNTEWGRKTSASLDGRYSGQFMNPANNPQGGADKNGPTA 666

Query: 648 SLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLN 707
            L S+++   A    G        PN   K     +  +  L D YF      +GG HL 
Sbjct: 667 LLNSLSRFD-AKYHGGSVQNIKFTPNMFNK----NRKIIKSLFDTYFK-----KGGCHLM 716

Query: 708 VNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQS 759
           V V++R +L DA ++PEKYP L +RVSG++  F +L ++ Q +V++R    +
Sbjct: 717 VTVVDRGVLKDAQDHPEKYPDLVVRVSGFSAIFVNLERDVQDEVMSRVLYDA 768


>UniRef50_A5ZSK3 Putative uncharacterized protein n=1 Tax=Ruminococcus obeum ATCC
           29174 RepID=A5ZSK3_9FIRM
          Length = 745

 Score =  437 bits (1123), Expect = e-121,   Method: Composition-based stats.
 Identities = 132/771 (17%), Positives = 250/771 (32%), Gaps = 109/771 (14%)

Query: 59  MEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGI-K 117
            E  K     ++    D +            + K+L++   LQ E P   +      I +
Sbjct: 10  EEYFKETKAVYSNYPTDVSR-----------MEKELDR---LQKENPKASSFQKKTWIYR 55

Query: 118 MIEGSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTP--DILRCRKSGVLTGLPDAYGR 175
                 +       P   +I T   +      F         L  +    + G  +  G 
Sbjct: 56  TAARDAEVILFPSSPFYAEIDTGREQNSVTASFPPQPGIGCWLMKQYPDFVDGYGEWSGY 115

Query: 176 ---------------GRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLENGVNL------ 214
                               +   +  YG+  +++    +             L      
Sbjct: 116 YGKYGVMNGPQFMDAAHHYANCETILKYGLSGIIRHARMRLEEKDLTDHQQDFLKCMIDV 175

Query: 215 --------EQTIRLREEI---AEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGY 263
                   E+     EE+         +  +K +A       S PA    EA+   +F  
Sbjct: 176 CRSLQRISERFAEKAEEMLKTEHDEEHVKALKMIAVTARRIPSEPAETFYEAMCAIWFTR 235

Query: 264 LAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPE 323
                         G     L  Y ERDLK  +IT  EAQE++D   + +   R+    +
Sbjct: 236 EMCNALDGLGFAVIGHLDRILISYYERDLKNNRITPDEAQELIDCF-VSMTDARWNLEAD 294

Query: 324 YDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLN 383
                + D       IGG   +G  +    S   +N+         P + +  S K P  
Sbjct: 295 LPGGTNAD-----IIIGGCDKNGDIVYNDISRMIINSYKK-YHFANPKLQVRISAKHPDE 348

Query: 384 FKKFAAKVS-IDTSSLQYENDDLMRPD--------FNNDDYAIACCVSPMIVGKQMQFFG 434
           F     +++ +  + L   NDD++ P          +   Y    C    +  +      
Sbjct: 349 FLLQVGELAGMGLNVLSIFNDDVIIPANQKQGKSLEDCRLYVAGGCQEICLSNEVNSRAY 408

Query: 435 ARANLAKTMLYAIN----GGVDEKLKMQVGPKSEPIKGDVLNYDEVM----ERMDHFMDW 486
              NL + +  ++       + ++   +  P       +  +++E      E   + +++
Sbjct: 409 TYLNLVQMLNGSLYPEYWNDIFKRDGFEFLP-----AANASDFEEFYHIVIENYRNELNF 463

Query: 487 LAKQYITALNIIHYMHDKYSYEASLMALHD--------RDVIRTMACGIAGLSVAADSLS 538
             K+Y    +    ++    + A++ +  +          V  T     AG     DSL 
Sbjct: 464 FVKKYNEYGSWWKIINPSLFFSATMPSCTETAKDVSEGGAVYNTDNFAAAGAGTVIDSLY 523

Query: 539 AIKYAKVKPI----------RDEDG---LAIDFEIEGEYPQFGNNDPRVDDLAVDLVERF 585
           AIK A  +              ED      +   +  + P+F  +     +    +++  
Sbjct: 524 AIKKAVYEDKITTFGHLLKAMKEDFRDDEILRQYLLHKVPKFCKDKD-ATEFGKKVMDDL 582

Query: 586 MKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGA 645
            + +     YR      S+    S   +   T  T DGR++ +    G NP    +    
Sbjct: 583 AECLGGQANYRGGKFEPSLFAFYSYNWFKNVTIATADGRKSESALSRGVNPSESTENINI 642

Query: 646 VASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQH 705
            A L ++  + +     G      I P         + +  A +M  +  +     GG  
Sbjct: 643 AALLDAIKTMDYTKYPGGAVIYMDI-PLMYKTP---QPSLFASVMRAFCEN-----GGSI 693

Query: 706 LNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTF 756
           ++ NV++R  LL+A +NPE +  + +RV GY+  F++LT E Q +VI RT 
Sbjct: 694 MDFNVISRNALLEAQKNPETHKNIVVRVCGYSAYFHTLTAEMQNEVIQRTQ 744


>UniRef50_A6CVH9 Formate C-acetyltransferase n=10 Tax=Bacteria RepID=A6CVH9_9VIBR
          Length = 763

 Score =  436 bits (1121), Expect = e-120,   Method: Composition-based stats.
 Identities = 143/776 (18%), Positives = 271/776 (34%), Gaps = 95/776 (12%)

Query: 47  ATEATTTLWDKVMEGV-KLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAP 105
             E    +  ++ME   +           + A  S +       I  + + +VG     P
Sbjct: 19  PCEKPAIMQLEIMEAYTRAHQSEENLYKREVACLSELYPVLFRQIESE-DIVVGRLDALP 77

Query: 106 LK-------RALIPFGGIKMIEGSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYT-PDI 157
           +          +  +     +E      + E    +  +   +++   + ++   T  + 
Sbjct: 78  IGFGSVTSVGGVGHYCNFDKLEAFKTELSPEEHSRVDVLLDYWKERDTRSIYFRQTLTEA 137

Query: 158 LRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLENGVN---- 213
              +   V            +  DY ++   GI  + +    +  S +A  +        
Sbjct: 138 TLGKFVDVNYPAIATARLSGMYLDYNKLIDNGIGGMRRLIGDKLDSARACHDTKAIALHE 197

Query: 214 ------------LEQTIRLRE---EIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQW 258
                       ++  I+L     E+        QM ++        +       + IQ 
Sbjct: 198 SFLGCFDIVEKVIDHHIKLCAKELEVTTDLTRKHQMNDLIDALNAIRNDKPQTFLQGIQL 257

Query: 259 TYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRF 318
           ++   L +        ++FGR   +L   +  DL+ G+ITE++A   +       R++  
Sbjct: 258 SWLYSLCS------GVVNFGRMDDYLGDLLVADLETGRITERQAINYIRSHY---RLIEA 308

Query: 319 LRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSE 378
            +T     +  G        +G    +   +  K +   +  +       EP  T+   +
Sbjct: 309 RKTTVNGRVVVGG-------LGRRNPETADVYCKLA---IQAVRE-NKDTEPQFTLRIYK 357

Query: 379 KLPLNFKKFAAK-VSIDTSSLQYENDDLMRPDF---------NNDDYAIACCVSPMIVGK 428
            +     + A + +    +     NDD+  P           +   Y    C   ++ GK
Sbjct: 358 GMNQGVYQDALEAIGEGLTYPILYNDDVNVPAVMNSMQISEQDAQHYVPFGCGEFVLSGK 417

Query: 429 QMQFFGARANLAKTMLYAINGGVDEKLKM-QVGPKSEPIKGDVLNYDEVMERMDHFMDWL 487
            +       N+ K +  ++ GG D      + G  S      V ++D+V++     +D+ 
Sbjct: 418 SVGTPNTCINILKILNISLTGGTDFWDGQNKSGGTSLLQPEQVTSFDDVIKNYKDLLDFY 477

Query: 488 AKQYITALNIIHYMHDKYSYEASLMALHDRDVIR------------TMACGIAGLSVAAD 535
            +    A    + + ++         L D  + R                   G + A D
Sbjct: 478 IELTSKAQAFSYQVMNQEVGFLFTSILTDDCIGRSKALLDGGVYKLGGTNETYGNTNAYD 537

Query: 536 SLSAIK---YAKVKPIRDEDGLAIDFEIEG---------EYPQFGNNDPRVDDLAVDLVE 583
           SL+AIK   +   K    E   A+    +G           P+FGN+D  VDD+AV++ E
Sbjct: 538 SLAAIKKVIFEDKKYSYSELIQALRVNFDGYDRMKYDLINAPKFGNDDAYVDDIAVEMHE 597

Query: 584 RFMKKIQKLHTYRDA-IPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQ 642
                I+              ++    N  +G+ T  + DGR  G       NP  G D+
Sbjct: 598 YICNGIKDSAAKVGMDSYLVVIINNQVNTEWGRATSASADGRHTGVYMSNANNPQSGADK 657

Query: 643 KGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEG 702
            G  A L S+AKL  A    G         N        ++  +  L+DGYF      +G
Sbjct: 658 NGPTAMLNSLAKLK-AEIHAGSVQNMKFSKNMYQN----KRMIVEALLDGYFE-----QG 707

Query: 703 GQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQ 758
           G  + V+V+ +  L DA  NPEKYP L +RV G++ +F +L K+ Q +++ RT   
Sbjct: 708 GPQIMVSVVGKGELEDAYHNPEKYPNLVVRVGGFSAKFVNLDKDVQLEILNRTLND 763


>UniRef50_D1NB06 Formate C-acetyltransferase n=1 Tax=Victivallis vadensis ATCC
           BAA-548 RepID=D1NB06_9BACT
          Length = 712

 Score =  432 bits (1112), Expect = e-119,   Method: Composition-based stats.
 Identities = 128/660 (19%), Positives = 224/660 (33%), Gaps = 81/660 (12%)

Query: 142 RKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQF 201
           R+               RC  +                 D+R V   G   + +D+  + 
Sbjct: 91  REHWRDEARRAMPEVAARCAANSERGLSLSQLDLSHTSPDWRNVLKLGPAGI-RDRAEKA 149

Query: 202 TSLQADLENGVNLEQTIRLRE-------EIAEQHRALGQMKEMAAKYGYDISGPATNAQE 254
                D E         R+          +A++    G ++ +          P    Q+
Sbjct: 150 LETAEDGEAREFFAAVARVYGAMCRYIVRLADEADRRGAVR-VTGALRVIAERPPETLQQ 208

Query: 255 AIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLR 314
           A+Q     +    + +     S G        +  RDL AG++  ++A+E++     K  
Sbjct: 209 ALQLALLYHH-TQELEGELVRSMGCFDRLFIGFYRRDLAAGRLNREQAKELLKFYWTKFF 267

Query: 315 MVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTI 374
                          G         GGM  DG     + +         +  + +P +++
Sbjct: 268 AQTQ-----------GKLWGKNFCFGGMDGDGSDACNELTELGFEVYREL-RTVDPKLSL 315

Query: 375 LWSEKLPLNFKKFAAKV-SIDTSSLQYENDDLMRPDFNND--------DYAIACCVSPMI 425
                LP      AA+      +++ + ND++ +  F           D+    C  P +
Sbjct: 316 RVHGGLPEKVLLQAAECVCRGRTAVVFANDEIAKEMFVRRGKLPEEIADFIPVGCYEPCV 375

Query: 426 VGKQMQFF-GARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFM 484
           +GK++        NLAK +   +                        ++ E++ER    +
Sbjct: 376 MGKELCCSMSTLFNLAKAVELLMEN-----------------PAPPRDFGELLERYLGLV 418

Query: 485 DWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTM------------ACGIAGLSV 532
                  +           + +    L    D    +                  AGL  
Sbjct: 419 REKLDDALELTRRWELRWPEINPSPLLSGTMDSCFEKGRDVSAAGTKYSSSGVMCAGLGS 478

Query: 533 AADSLSAIKYAKVKP---IRDEDGLAIDFEIEGE----------YPQFGNNDPRVDDLAV 579
           AADSL+A++    +      +E    +  + EG            P++GNN P  D LA 
Sbjct: 479 AADSLTALRILLFEERRCTWEELRATLKADWEGREPLRLYVSGRLPKWGNNLPEPDALAR 538

Query: 580 DLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHG 639
            + +   ++I +    RD      + +I     YG+ TG TPDGRRAG P          
Sbjct: 539 KIADAVAERINRAPNARDGFFQTGMWSIDWAQRYGRMTGATPDGRRAGEPLSKNLGAAIA 598

Query: 640 RDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEAS 699
           +D++G  A L S AKL  A   DG      + P+ +   +  +   +A L+  YF     
Sbjct: 599 KDRRGVAALLHSAAKLDQAEFPDGAVLDVMLHPSMVKGKEGPKV--VADLVRTYFEA--- 653

Query: 700 IEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQS 759
             GG  +  N+++ + L  A   PEKY  + IRV G+ VRF  L    Q+  I    ++S
Sbjct: 654 --GGLFIQFNILDVDTLRRARREPEKYSSVQIRVCGWNVRFIDLDPAAQELFIQEAESKS 711


>UniRef50_C0CUZ2 Putative uncharacterized protein n=1 Tax=Clostridium asparagiforme
           DSM 15981 RepID=C0CUZ2_9CLOT
          Length = 759

 Score =  431 bits (1108), Expect = e-119,   Method: Composition-based stats.
 Identities = 126/683 (18%), Positives = 227/683 (33%), Gaps = 88/683 (12%)

Query: 132 PMIKKIFTEYR-KTHNQGVFDVYTPDILRCRKSGVLTGLPDAY----GRGRIIGDYRRVA 186
             +  +   ++  + N  V       I     S      P              D+ ++ 
Sbjct: 108 EDLHDLLIFWKTNSSNNKVLRNTPDSIKHILFSDNWKQTPLPASPIIRMAGAYLDFDKLI 167

Query: 187 LYGIDYLMKDKLAQFTSLQADLENGVNLEQTIRLREEI-----------------AEQHR 229
             G+  +  +  A     + +  + V  +      E +                 A   +
Sbjct: 168 RLGLPGMRAEVTAYRERAEQEGGDAVLYQCMDGALELMGQVCLWYRDQAMELLAQAGDEK 227

Query: 230 ALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIE 289
             G+++ MA            +  EA+Q  +   + A   Q      FGR   +L  +  
Sbjct: 228 RKGELRRMAQALEAIAERAPGSMMEALQLVWIYGIMAPLLQ------FGRLDVYLGDWYA 281

Query: 290 RDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTL 349
            D+  G +TE+EA  ++     ++  +                      +GG G      
Sbjct: 282 HDIDNGVLTEEEALALLQSYFRQIDSLD-------------SETDCRVIVGGYGRRNPEN 328

Query: 350 VTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSI-DTSSLQYENDDLMRP 408
             +     L    T+     P  T+ ++ + P      A +      +     NDD++ P
Sbjct: 329 ADRLCMTALEACRTV-REILPQFTLRFNRETPECVWDAAMRCIEEGRTYPLLYNDDVLVP 387

Query: 409 DFN---------NDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQV 459
                        + Y    C                 N  K +  A+ GG +  +   +
Sbjct: 388 GLMNAFHVSRERAETYVPLGCGEMEFDHYSFGTPSGSLNTLKILELAVRGGYEPIMDWHL 447

Query: 460 GPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDV 519
           G + +PI      ++E  +     +    +         + +  K      +  L+D  +
Sbjct: 448 GKQLKPIT-QCNTFEEFFQVYKENLQHYIEAQAIFEKYEYEITGKMHSFMYVSMLYDGVL 506

Query: 520 IRTMAC------------GIAGLSVAADSLSAIKYAKVKP---IRDEDGLAIDFEIEG-- 562
               A              + G+  A +SL+A+K    +      ++   A++    G  
Sbjct: 507 ESGKAIFDGGCRYLAGTLELYGVVNAVNSLAAVKKLVYEDRTVSAEDLLRAMNDNFVGWE 566

Query: 563 -------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSV-LTITSNVVYG 614
                  + P++GN+D  VD + V+L +   K I             +V +    N   G
Sbjct: 567 VLRRQLLDVPKYGNDDDYVDRIFVELHDWLCKTISSQAEKVGLKSYLAVNINNAQNTTLG 626

Query: 615 KKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNA 674
           +  G TPDGR+AG P     NP  G D+ G  A L S+ K P      G+     +    
Sbjct: 627 RWVGATPDGRKAGMPMANANNPSSGSDKNGLTAMLNSILK-PRHDNHAGMVQNLRLSRET 685

Query: 675 LGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVS 734
                E  +  + GL+  YF       GG HL + V+ +E L  AME+PE Y  L +RV 
Sbjct: 686 F----EQNREKVKGLIRNYFD-----RGGAHLMITVVGKEDLKKAMEHPEDYQDLIVRVG 736

Query: 735 GYAVRFNSLTKEQQQDVITRTFT 757
           G + R+  L K+ QQ++  R   
Sbjct: 737 GLSARYVQLKKDVQQEIYDRATY 759


>UniRef50_A7VPJ9 Putative uncharacterized protein n=1 Tax=Clostridium leptum DSM 753
           RepID=A7VPJ9_9CLOT
          Length = 725

 Score =  421 bits (1083), Expect = e-116,   Method: Composition-based stats.
 Identities = 140/689 (20%), Positives = 245/689 (35%), Gaps = 78/689 (11%)

Query: 117 KMIEGSCKAYNRELDPMIKKIFTEYRKT----HNQGVFDVYTPDILRCRKSGVLTGLPDA 172
           ++I  + +    E D    ++     ++      + V+  YT           L   P  
Sbjct: 67  RIIGRAYQVRFAEPDCYDPELKDYSLQSPGFESGEAVYKGYTD-----LAELHLVTEP-- 119

Query: 173 YGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLENGVNLEQTIRLREEIAE-QHRAL 231
             RG I  D+ ++   G + L         S + DLE        +   E + +   + +
Sbjct: 120 -ARGHITWDWTKILRLGTEGLKAQYENALHSAK-DLEAEHFYRGVLIALEALEDWNDQHV 177

Query: 232 GQMKEM-----AAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDV 286
             +++M     A    +    PA   +EAIQ  +  YLA            G+   +L  
Sbjct: 178 AYLRKMGKQELADLCQHVPRHPARGFKEAIQSFFMQYLAVFYENPFGGNGPGQFDKYLWP 237

Query: 287 YIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDG 346
           Y+++DL+ G  T +EA+E+V+ L ++L             + + D        GG   DG
Sbjct: 238 YLKKDLENGSCTLEEAEELVEELFIRLDE----------RVSANDLWNEMIITGGTHRDG 287

Query: 347 RTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAK-VSIDTSSLQYENDDL 405
            + V+  S   ++ +  +  +  P + +   +     + K  AK +    +  Q   D  
Sbjct: 288 SSAVSPLSKIMVDAIMKLNIT-HPTVYMRVPKDADEEYVKLCAKYLKYGNNRAQIYYDPN 346

Query: 406 MRPDF---------NNDDYAIACCVSPMIVGKQMQFF-GARANLAKTMLYAINGGVDEKL 455
           +             +  +Y +  C+   I G        A  N+   +  AI GG     
Sbjct: 347 VIRALTETDGVRPEDATEYGVGGCLEIGIQGMNDDLLQCAWVNMPLMLELAITGGYSLSE 406

Query: 456 KMQVGPKSEPIKG--DVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMA 513
           + QV     P+ G      ++   +    F D L     + +       +KY     + +
Sbjct: 407 RKQVDSAGIPLPGLAQHNTFESFYKNYLDFTDRLVGISFSMIERQSIHDEKYRPAYLISS 466

Query: 514 LHDRDVIRT--MACGIA----------GLSVAADSLSAIKYAKVKP---IRDEDGLAIDF 558
           + D  + R   M  G A          G+    D L AI+ A         +E   A+  
Sbjct: 467 MIDDCLERGRHMHAGGARYHDYSMTPLGIPNVIDGLYAIRTAVFDQHICTAEELVSAMRA 526

Query: 559 EIEG---------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITS 609
           + +G           P++G  +   DD A  +V    K           I    VLT   
Sbjct: 527 DFKGYERLQRQLRAIPKYGQENDDADDFARTVVTDIAKMFVTRRNRFGGIFRPMVLTFIY 586

Query: 610 NVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFS 669
             +   + G T DG         G  P       G  A++ S  K+PF Y   G S  + 
Sbjct: 587 APLAAAQLGATADGNNMHTMVAQGLTPQSRSMSCGITAAMNSCTKMPFYYFSGGASTMWD 646

Query: 670 IVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQL 729
           + P+         +  +A L+  +FH+     G Q    N  + + L++A ++PE Y  L
Sbjct: 647 LDPHW------ASEKLIADLLMTFFHN-----GAQVFQGNTTDVKELIEAQKHPEDYEHL 695

Query: 730 TIRVSGYAVRFNSLTKEQQQDVITRTFTQ 758
            +RV G++ RF  LT   Q D+I R    
Sbjct: 696 IVRVGGFSARFVGLTPGLQTDIINRRRHN 724


>UniRef50_B0NGB8 Putative uncharacterized protein n=3 Tax=Bacteria
           RepID=B0NGB8_EUBSP
          Length = 794

 Score =  409 bits (1051), Expect = e-112,   Method: Composition-based stats.
 Identities = 153/732 (20%), Positives = 254/732 (34%), Gaps = 103/732 (14%)

Query: 94  LEKIVGLQTEAPLKRALIPFGGIKMI-EGSCKAYNRELDPMIKKIFTEYRKTHNQGVFDV 152
           ++   G      +   + P G I        K YN   D   K +   Y       +   
Sbjct: 97  VDSFTGYCDPVAVFGDIDPMGDITQERIDDLKEYNMNTD-FAKALCKAY------DIAGE 149

Query: 153 YTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLENGV 212
            T +        +          G +I D R V   G+D L K+++ +  + +AD +   
Sbjct: 150 NTSE-------AIFFIEQ---VTGHLIPDMRPVLKIGVDGL-KEQIRRHKAAEADADKKD 198

Query: 213 NLEQT----------IRLREEIAEQHRAL------GQMKEMAAKYGYDISGPATNAQEAI 256
             +                EE+A +  A        + + MA   G      A+N  EAI
Sbjct: 199 YYDAMDIALDAVLVIAGRYEELAREKAAKSEGAVKERFEVMADALGKVPRQGASNLYEAI 258

Query: 257 QWTYFGY--LAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLR 314
           Q     +  +   ++ N  A S G      + Y        +  E   ++M   L+  L 
Sbjct: 259 QSFILMWQVMCLEQTPNPYAFSVGNADRIFEPY--------RQAEDTGRDMTAALLKHL- 309

Query: 315 MVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTI 374
            + F    +     S         IGG    G  +    S+  L+  Y M   P+P +++
Sbjct: 310 -LVFYNVADRSWAIS-----QDLIIGGKSNTGEDMTNPTSYALLDAYYDMN-LPQPILSV 362

Query: 375 LWSEKLPLNFKKFAAKVSI--DTSSLQYENDDLM---------RPDFNNDDYAIACCVSP 423
              +  P    +   +        +  + NDD +             + +DY++A C  P
Sbjct: 363 KLHKDTPDELYESLGRFLFTPGCLTPSFFNDDSVFEILKEKNHVEPEDLEDYSVAGCQEP 422

Query: 424 MIVGKQMQ-FFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMER--- 479
           +I+GK       +  N+AK +  ++NGGV      + G  +E          +V++    
Sbjct: 423 LIMGKDNGNTTNSWLNMAKVLELSLNGGVSTISGRKFGKSNEENGYKEEV--DVLKNIRS 480

Query: 480 -MDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDR--------------DVIRTMA 524
                ++    Q +   N              L AL                        
Sbjct: 481 TFYQNLEEYVDQMVECANAASEAIS-LLQVPFLSALMGGIETGIDTRDTRNQGTKYNGSG 539

Query: 525 CGIAGLSVAADSLSAIKYAKVKPIRDE--DGLAIDFEIEGEY---------PQFGNNDPR 573
           C I GLSV ADS +AI     +  +D      A+    E +           ++GNN   
Sbjct: 540 CLIHGLSVVADSFAAIDRLLEERPKDAGRMLEALRDNFEHDQQMRQYLMKAEKYGNNTAN 599

Query: 574 VDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPG 633
           VDD A ++  R    +     Y          + +++++YG   G TPDGR A    G G
Sbjct: 600 VDDEAAEIAARVSDMVSSKKNYLGNPFRADWASPSTHLLYGYWVGATPDGRMAREQLGYG 659

Query: 634 ANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDD-EVRKTNLAGLMDG 692
            +P++G    G    + S  KLPF     G +    I PN       E +       + G
Sbjct: 660 IDPLYGEAHSGLGFRIMSNMKLPFEKMNGGCASHLGINPNYFKTSSYEEKGLEFKNKIIG 719

Query: 693 YFHHEASIEGG--QHLNVNVMNREMLLDAMENPEKYPQ---LTIRVSGYAVRFNSLTKEQ 747
              +    EG    +L VNV   EML   + +P+KY       +R+ G  V F  L+ + 
Sbjct: 720 PLFYNPKKEGISPFYLYVNVTTPEMLRKVLADPKKYAPSGVYIMRIHGTFVNFLDLSPDI 779

Query: 748 QQDVITRTFTQS 759
           Q+D+I R   +S
Sbjct: 780 QEDIIKRLDMES 791


>UniRef50_D1N5W4 Formate C-acetyltransferase n=1 Tax=Victivallis vadensis ATCC
           BAA-548 RepID=D1N5W4_9BACT
          Length = 783

 Score =  405 bits (1042), Expect = e-111,   Method: Composition-based stats.
 Identities = 143/719 (19%), Positives = 241/719 (33%), Gaps = 91/719 (12%)

Query: 93  QLEKIVGLQTEAPLKRALIPFGGIKMI-EGSCKAYNRELDPMIKKIFTEYRKTHNQGVFD 151
           Q+E  VG      +   + P   I      + + Y RE  P +K++   Y KT       
Sbjct: 96  QVESFVGYCDPVAIYADIEPSEAIPAERIEAVRNYYRET-PYVKRLTAIYEKT------A 148

Query: 152 VYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLENG 211
             T ++    +             G +I D R +   G++  +    A    +    E  
Sbjct: 149 ALTDEVTFFMEP----------VTGHMIPDMRPILAQGLEAFVAAAPADTPFVAVMREAA 198

Query: 212 VNLEQ----TIRLREEIAEQHRA----LGQMKEMAAKYGYDISGPATNAQEAIQWTYFGY 263
                       L E +AE+  A      ++K +AA         A N  EA+Q     +
Sbjct: 199 RAAAILAGRYAELAETLAEERAAMPGEAERLKLIAANCRQVPVRKARNLHEAMQSYLLLW 258

Query: 264 --LAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRT 321
             +   ++ N  A S G      + Y+      G    + A  +  HL++      F   
Sbjct: 259 QLMCLEQAPNPYAFSAGNLDRVFEPYLA---GTGF---ESAVALTRHLLV------FYMV 306

Query: 322 PEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLP 381
                  S         +GG  L G  L    +   L   +     P+P +++      P
Sbjct: 307 GARGWAIS-----QNLLLGGRDLAGNDLGCGMTDVILEAFFRSNQ-PQPALSVKIHRNSP 360

Query: 382 LNFKKFAAKVSI--DTSSLQYENDDLM--------RPDFNNDDYAIACCVSPMIVGKQMQ 431
               +   +       S+    NDD+M          D +  D+A+A C  P+I+GK+  
Sbjct: 361 ERLFRNMGRFYFTPGHSTPSLFNDDMMFRVLKSKGIADADIPDWAVAGCQEPLIMGKENG 420

Query: 432 -FFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGD--VLNYDEVMERMDHFMDWLA 488
               +  NLAK +   +N G       ++G  +  +  D     Y ++       +D + 
Sbjct: 421 NTTNSWLNLAKVLELVLNDGCSLLTGRRIGLSAAELGYDSPEAAYRDLETAFFRQLDHVL 480

Query: 489 KQYITALNIIHYMHDKYSYEASLMALHDR--------------DVIRTMACGIAGLSVAA 534
                A N        ++       L                        C I GL V A
Sbjct: 481 PFMEAAANRCTRAIGGWA-TPFGSLLFGGLESGRDMRDPERPGTRYSGSGCLIHGLGVVA 539

Query: 535 DSLSAIKYAKVKPI--RDEDGLAIDFEIEGE---------YPQFGNNDPRVDDLAVDLVE 583
           DSL A+K+   +     D    A+                YP++G+  P  D+ A  +  
Sbjct: 540 DSLVAVKHFLAEQPGGADSLRAALRNNFADAPALRARLLAYPKYGSVLPEPDETAARIAS 599

Query: 584 RFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQK 643
               K+  L             T +++++YG   G TPDGR A A  G G +P       
Sbjct: 600 VVSDKVYALRNPAGRPFMPDFSTPSTHLLYGYWVGATPDGRPARAMLGYGVDPRPEVTNS 659

Query: 644 GAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLA---GLMDGYFHHEASI 700
                L S   LPF     G +    + P A     E+ +  +A    ++   F   A  
Sbjct: 660 ELTDQLLSERGLPFGKMVGGYASHIGLAPAAFADRAELEEKGVAMRDRVIRPLFAAGAEG 719

Query: 701 EGGQHLNVNVMNREMLLDAMENPEKYPQ---LTIRVSGYAVRFNSLTKEQQQDVITRTF 756
           E   ++  N+ + + L   + +P +Y       +R+ G  V F  L    Q+D+I R  
Sbjct: 720 EAPYYVYFNIDSAKHLRKILTDPARYVPSGIYIMRIHGTFVNFLDLAPAIQEDIIKRLE 778


>UniRef50_C7ILA9 Formate C-acetyltransferase n=1 Tax=Clostridium papyrosolvens DSM
           2782 RepID=C7ILA9_9CLOT
          Length = 866

 Score =  404 bits (1038), Expect = e-111,   Method: Composition-based stats.
 Identities = 127/782 (16%), Positives = 232/782 (29%), Gaps = 183/782 (23%)

Query: 148 GVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQAD 207
            VF  Y  +    +++G  T   +    G    +Y  +   G++ ++K+   +   L++ 
Sbjct: 97  KVFPNYLTE--NEQRAGAFTNKTELSLLGHNSVNYDNLLDKGLNAIIKEAEEKLEDLKSV 154

Query: 208 LE-----------NGVNLEQTI--------------RLREEIAE------QHRALGQMKE 236
            E                   I               L  E+A+            ++ E
Sbjct: 155 GEMFETGDDKRKNAIDFYNAVIISCSSVIEYSLKFADLAGEMAKGLTDPKDGARKKELLE 214

Query: 237 MAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGK 296
           +                EA+Q  +  + A   S N   +S GR    L  Y+++D    K
Sbjct: 215 IERICRKVPMEKPDTFHEALQSIFTFHTALHASLNY--LSLGRLDQVLVKYLDKD----K 268

Query: 297 ITEQE----AQEMVDHLVMKLRMVRFLRT------------------PEYDELFSGDPIW 334
           IT+++      E+ +  ++K      + T                  P Y +  +G   +
Sbjct: 269 ITDEDYLKKCTELFECFIIKAAWRLNMTTEYLVEQDHMDHNAALGVHPYYIDQRAGVNNF 328

Query: 335 -ATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSI 393
                +GG   DG+  V K ++  LN    +  S  P +      +     KK  A++  
Sbjct: 329 LQNIIVGGKTPDGKDAVNKMTYIILNAFENVNLST-PGIYARLHSQSDDKLKKRVAEMLS 387

Query: 394 DT-SSLQYENDDLMRPDFN----------------------------NDDYAIACCVSPM 424
            T +     NDD++ P                                +DY +  C  P+
Sbjct: 388 KTKNLPGILNDDVLIPAMFNGLRENDVDLDITKVKSFSGKEAEYMRLANDYCVDGCWEPI 447

Query: 425 IVGKQMQFFGARANLAKTMLYAINGGV--DEKLKMQVGPKSEPIKGDVLNYDEVMERMDH 482
           + G     FG   N    +   +N G   D    M  G K   I     +Y+   +  + 
Sbjct: 448 LNGNSDWTFG-MLNGMTILQCTLNRGATLDTNPGMLRGGKMSFISDVPTDYNSFKKIFEK 506

Query: 483 FMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIA------------GL 530
            M +   Q    L   + + +  +      ++    + +                   G+
Sbjct: 507 QMQFFIDQSTFGLYEYYMLDEFVNPSPLFSSVFGGCMQQGRDKSWGGAEYNLGGTILIGI 566

Query: 531 SVAADSLSAIK---YAKVKPIRDEDGLAIDFE---------------------IEGEYPQ 566
               ++L+AIK   + + K    E   A+                             P+
Sbjct: 567 PDMINTLAAIKKWVFDEKKYSLQEVLDAMRSNFVSPAKENVILQKRYDSIRIDFNTNTPK 626

Query: 567 FGNNDPRVDDLAVDLVERFMKKIQKLH--------------------------------- 593
           FG ND  + ++   ++E +   I+                                    
Sbjct: 627 FGENDKEISEIGSYIIETYCNSIKSSKKLADKVFLIPLREFSEKEKAEILRLRKICGYFG 686

Query: 594 ----TYRDA----IPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGA 645
                          T    T     + G     +PD R +  P  P  +P  G  QK  
Sbjct: 687 NSLQNKFGKDFNIRFTAGCGTFEQYPLQGLGIVASPD-RNSNDPLAPNLSPYPGTVQK-P 744

Query: 646 VA-SLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNL-----AGLMDGYFHHEAS 699
            A  L S+  L       G      I   A   +      N        +M      +  
Sbjct: 745 TAHILESLKALNLNKLAAGAITDLCIDYKANNVEHIAGIINKFIESDGNMMTLAIGDKEE 804

Query: 700 IEGGQHLNV---NVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTF 756
            +    L+V   N  ++E    A E  E+Y  + +RV G+   F S++ +QQ+  I R  
Sbjct: 805 YQKIYELSVTASNSSDKEASKAAYEKLEQYKHVNVRVGGWQAPFVSMSLDQQKSYILRIL 864

Query: 757 TQ 758
            +
Sbjct: 865 EE 866


>UniRef50_B9M4R7 Formate C-acetyltransferase n=2 Tax=Bacteria RepID=B9M4R7_GEOSF
          Length = 853

 Score =  403 bits (1037), Expect = e-110,   Method: Composition-based stats.
 Identities = 118/753 (15%), Positives = 217/753 (28%), Gaps = 152/753 (20%)

Query: 148 GVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMK-------DKLAQ 200
            VF  Y  +    +++  +T   +    G    DY R+  YGI  +++       +  A+
Sbjct: 98  KVFPNYLTE--DEKRAARITNRTELSLLGHNTADYDRLVRYGIRGILETCESKSAEIKAK 155

Query: 201 FTSLQADLENGVNL-------EQTIRLREEIAE----------QHRALGQMKEMAAKYGY 243
               + D              E  +      A+            R   ++ E+      
Sbjct: 156 QPLTEDDQNKLDFYRAVRIASEAVVEYAGRFADLARDKGRTESDLRRRAELAEIERICRK 215

Query: 244 DISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQ 303
               PA    EA+Q  +F + A   S N   +S GR    L  Y+   ++ G     +  
Sbjct: 216 VPLEPADTFHEALQSIWFVHTALHASMN--LISLGRLDQVLAPYLASTVEKGVYDPAKGV 273

Query: 304 EMVDHLVMKLRMVRFLRT------------------PEYDELFSGDPIW-ATESIGGMGL 344
           E+ +  ++K        T                  P Y +  +G   +     IGG+  
Sbjct: 274 ELFECFLIKAAWRLNYTTEYLVQQDHMDYNAALGVNPYYLDQRAGANNFLQNVIIGGLKP 333

Query: 345 DGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSS-LQYEND 403
           DG       +F  L     +   P P + +      P N K   A+   +T +     ND
Sbjct: 334 DGSDATNDCTFVILRAYRNVN-LPTPGIYVRMGSSSPENLKFAVAESLHETGNNPSILND 392

Query: 404 DLMRPDFNN---------------------DDYAIACCVSPMIVGKQMQFFGARANLAKT 442
           D++ P                         +DY +  C  P++ GK    FG   N    
Sbjct: 393 DVLIPALYRAFCEGEDPTDRARLAELKAVVNDYCVDGCWEPILNGKSDWTFG-MINGMTI 451

Query: 443 MLYAINGGV--DEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHY 500
           +  ++N G   D       G K     G++ +Y  + E +   + +   Q    L   + 
Sbjct: 452 LECSLNKGATLDNNPGTLRGGKLSYSSGEIASYGALRESLRGHLQFFVDQSAFGLYKYYM 511

Query: 501 MHDKYSYEASLMALHDRDVIRT------------MACGIAGLSVAADSLSAIKYAKV--- 545
             +         A     + R                 + G+    +++ A+K       
Sbjct: 512 TDEYVVPCPLFSAFLGTCLERGRDKAWGGAEYNIGGTILTGVPNMVNTVCAMKKWVFDEG 571

Query: 546 KPIRDEDGLAIDFEI---------------------EGEYPQFGNNDPRVDDLAVDLVER 584
           K   D+   A                              P FG+N P  + +   +++ 
Sbjct: 572 KYHLDDVLEAFRNNFVSPQTTNPASQRTYDAIRVDFATNSPLFGSNHPEANAVTRWILDD 631

Query: 585 FMKKIQKLHTYRDAI------------------PTQSVLTITSNVVYGKKTGNTP---DG 623
           +   +    +  D I                          +    +G +         G
Sbjct: 632 YFDAVMSSKSMADRIFLKKPATTEEEREVKRLRYIAGYFGESFQEKFGPQFNIKFTAGCG 691

Query: 624 RRAGAPF-----------------GPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISY 666
                P                   P   P  G    G    L S + L       G+  
Sbjct: 692 TFEQYPLQGAGIAASADRAAAAPLAPNFTPPPGTQINGIGNLLASFSGLGLDRLGAGVIT 751

Query: 667 TFSIV-----PNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAME 721
              +      P  +    E    N   +M     + A  +    L+          +A+ 
Sbjct: 752 DLCLDQSQNDPEVIRGIMEQFIANKGNMMTLAIGNSAVYQTIYELSWAASKMSDQTEAVR 811

Query: 722 NPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITR 754
             E+Y  + +RV G+   F +++ +QQ++ I R
Sbjct: 812 KLEEYSAINVRVGGWQAPFITMSLDQQENYINR 844


>UniRef50_D1N9D9 Formate C-acetyltransferase n=1 Tax=Victivallis vadensis ATCC
           BAA-548 RepID=D1N9D9_9BACT
          Length = 748

 Score =  402 bits (1033), Expect = e-110,   Method: Composition-based stats.
 Identities = 120/687 (17%), Positives = 223/687 (32%), Gaps = 96/687 (13%)

Query: 147 QGVFDVYTPDILRCRKSGVLTGLPDA------YGRGRIIG---------DYR-------R 184
            G  ++ +   L  R   + +  P+       Y  G +IG         DY         
Sbjct: 82  DGCVNLSSGGWLYLRNVALYSDSPEKAADYRRYCYGDLIGLHLSYGPYYDYDHHCFPFSN 141

Query: 185 VALYGIDYLMKDKLAQFTSLQADLENGVNLEQTIR--LREEI---------------AEQ 227
           +   G+  ++K +L +  +   + E     E   R  L                   AE 
Sbjct: 142 MLELGLSGILK-RLEEGHARNTEPEKAEFYEAARRGILAVRKIAEKFAAAAEEKLASAES 200

Query: 228 HRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVY 287
                 ++ +          P     E ++  +F +              G     L   
Sbjct: 201 PEERKNLERIRTAARRIPWNPPQTFYEGLECLWFFHELGSVLDGIGMSVLGSPDRQLIRL 260

Query: 288 IERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGR 347
             RD++  ++TE EA E++  L M     +       +  F+      T  +GG+   G 
Sbjct: 261 YRRDIQEKRLTEAEAYELI-CLYMLQTDSKLDFDRPIEGQFNAGEQGDTLILGGLDESGN 319

Query: 348 TLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAK-VSIDTSSLQYENDDLM 406
            +  + +F FL     +     P + I +S + P    + AAK    D + L + NDD++
Sbjct: 320 DVTNELTFLFLKAHREL-KLTYPKIHIRFSSRTPAVLFQEAAKDFLADRNVLSFLNDDIV 378

Query: 407 RPDFN--------NDDYAIACCVSPMIVGKQM-QFFGARANLAKTMLYAINGGVDEKLKM 457
            P              Y    C   ++ G +  Q   +  +L K +  +I+   + + + 
Sbjct: 379 IPSQIMAGKTPESAARYVAGGCWENILEGYEHSQGANSYFSLGKCVDLSIHE--ENEDEK 436

Query: 458 QVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDR 517
            +      + G   +++ V   +   +     Q  +       +  + +      A  + 
Sbjct: 437 SLELPFRKLDGA-TSFEGVYSIVMDNIKLALHQLFSIQQKYGALWTQVNPCPFFSACLNG 495

Query: 518 DVIRTM------------ACGIAGLSVAADSLSAIKYAKV---------------KPIRD 550
                                  G++V  DSL A+K                      RD
Sbjct: 496 CAESGRDYSAGGACYSPHGIPFTGVAVLVDSLLALKTICFGENPVPLPRLLAVIRNDWRD 555

Query: 551 EDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSN 610
            + L          P  G+       L   ++      +         I    + +    
Sbjct: 556 AEALRCRAM---ASPHLGDGKGEAARLTARILNDLADYVAGFRNELGGIYQCGLYSYRDI 612

Query: 611 VVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSI 670
           + + K T  TPDGRRAG     G  P             +  A LP          T S+
Sbjct: 613 IDWAKVTRATPDGRRAGDFLSQGLTPAR-THADAVTQVFSDTASLPLLRFPANSVLTLSL 671

Query: 671 VPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLT 730
             N L +           L+ G+      + G   L +N ++RE L DA +NP+ +  L 
Sbjct: 672 SKNGLTE----------ALLSGFLKAWVLVRGSGMLQLNCISREELEDAQKNPQNHASLI 721

Query: 731 IRVSGYAVRFNSLTKEQQQDVITRTFT 757
           +R+ GY+ +F +L++E+Q++ I+R   
Sbjct: 722 VRLYGYSAKFITLSEEKQREFISRNIY 748


>UniRef50_D1N4L3 Formate C-acetyltransferase n=1 Tax=Victivallis vadensis ATCC
           BAA-548 RepID=D1N4L3_9BACT
          Length = 716

 Score =  401 bits (1031), Expect = e-110,   Method: Composition-based stats.
 Identities = 134/621 (21%), Positives = 232/621 (37%), Gaps = 80/621 (12%)

Query: 175 RGRIIGDYRRVALYGIDYLMKDKLAQFTS----------LQADLENGVNLEQTIRLREEI 224
                 DYR     G   L +       +          L A+LE    +   I      
Sbjct: 135 DAHFAPDYRIGLSLGWGGLTRKVERSLEAHKFDSEAVELLNAELEALAGIRNWIHRTAMA 194

Query: 225 AEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWT-YFGYLAAVKSQNGAAMSFGRTSTF 283
           AE     G+++ +  +   D   P    +EA QW  +F   +   +++GA    G+    
Sbjct: 195 AE-----GELRRINLRLEND---PPETLREACQWIAWFNMASRTYNRDGAG---GQLDEI 243

Query: 284 LDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMG 343
           L  Y ERD+ AG+I +++A   +  L++          P Y +            IGG  
Sbjct: 244 LRPYYERDIAAGRIDDEDAVYYIACLLL--------NDPHYYQ------------IGGPD 283

Query: 344 LDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSID--TSSLQYE 401
            +G+   ++ SF  L   + +      N+TI   +++     +   ++ ++      ++ 
Sbjct: 284 PNGKDQTSRISFLILEAAHALK--TPCNLTIRVHDRMDEKLFRRGVEILLEDNLGYPRFS 341

Query: 402 NDDLMRPDFNNDDYAI--------ACCVSPMIVGKQMQFFG-ARANLAKTMLYAINGGVD 452
            D+ +   F  + Y+I          C    I G++       + N+ K    A N   D
Sbjct: 342 GDNALIEGFMRNGYSIELARERIALGCNWMSIPGREYTLNDTVKINMMKVFEVAFNEIAD 401

Query: 453 EKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLM 512
              K  +G   +  +  +      +     F   LA QY     ++  +      E    
Sbjct: 402 SG-KFSLGALHKCYQKHLARAAFCIAEGLDF--HLAHQYRNEPELLLNLLCYGPIEKGRD 458

Query: 513 ALHDRDVIRTMACGIAGLSVAADSLSAIKYAKVKPIR---DEDGLAIDFEIEGE------ 563
           A H       M C  AGL+V ADS +A++   V+  R    E   A+  +   E      
Sbjct: 459 ASHGGVDFYNMCCDGAGLAVVADSFAALQTQVVERKRIAWKECVEAVRSDFRNENGEQIR 518

Query: 564 -----YPQFGNNDPRVDDLAVDLVERFMKKI-QKLHTYRDAIPTQSVLTITSNVVYGKKT 617
                 P+FG+     D+ AV L   F +       T    +    + +    + +GK  
Sbjct: 519 RLLASSPRFGHGGTCADEWAVTLTHDFAETFPNGRRTPEGRLIIPGLFSWADTLRFGKTV 578

Query: 618 GNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGK 677
           G TP+GRRAG P   GANP  G  + GA  ++            +       +  + +  
Sbjct: 579 GATPNGRRAGEPSSHGANPCPGFRKDGAATAVAKAVASVQCGYGNTSPLQLELDASFVNC 638

Query: 678 DDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYA 737
            D V +  L  L   +F       GG  +NVN+++ + L  A + PEK+P L +RV+G+ 
Sbjct: 639 ADPVGR--LTALFRTHFKL-----GGTLINVNIVDAKTLRAAQKEPEKFPDLIVRVTGFT 691

Query: 738 VRFNSLTKEQQQDVITRTFTQ 758
             F  L+ E +  V+ R   +
Sbjct: 692 SYFIMLSPEFRDFVVKRIIEE 712


>UniRef50_C3Z558 Putative uncharacterized protein n=3 Tax=Branchiostoma floridae
            RepID=C3Z558_BRAFL
          Length = 1619

 Score =  401 bits (1030), Expect = e-110,   Method: Composition-based stats.
 Identities = 115/793 (14%), Positives = 232/793 (29%), Gaps = 172/793 (21%)

Query: 121  GSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIG 180
                 Y    D +I  +   +     + V    T +    +      G+ +A   G ++ 
Sbjct: 454  DQFDLYRIHPDELIVGVMPSFSMGLGKRVMPYLTDE---EQIPAYQMGVTEAAAIGHVVP 510

Query: 181  DYRRVALYGIDYLMKDKLAQFTSLQ---------------------ADLENGVNLEQTIR 219
            DY+ +   G+  L+ D   + + L+                     + +     ++   +
Sbjct: 511  DYQVILDKGLQALIDDIDDKLSKLETLVLSRREEKERAMFYHSIKMSLMGVQEYIKSYAQ 570

Query: 220  LREEIAEQHR----ALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAM 275
            L + +A+          +++++  +     +       EA Q  +  +        G  +
Sbjct: 571  LADNLADNETFTKAQATKLRQIGHRMSTLATHKPKTFLEATQLVFTMHCCLHIV--GEPI 628

Query: 276  SFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFL-RTPEYDELFSG---- 330
            S GR    L  +  +D     +T +EAQE++D   +K+     L R    D++F G    
Sbjct: 629  SIGRLDQLLGPFYRQD----SLTMEEAQEIIDCFWIKVGERTLLNRHAAQDKIFPGMGAV 684

Query: 331  --------------DPIWATESIGGMGLDGR----TLVTKNSFRFLNTLYTMGPSPEPNM 372
                          +      +IGG   +      +     +   L     + P   P +
Sbjct: 685  PYTSSGNFPQGGCMNQWGQQLTIGGYLPNEDTVPTSACNPVTLMCLRAARRL-PLNAPCL 743

Query: 373  TILWSEKLPLNFKKFAAK-VSIDTSSLQYENDDLMRPDF-------------NNDDYAIA 418
            T+  ++  P    + AAK +    +     +DD + P               +  +Y   
Sbjct: 744  TLRLNKDTPEEVLEEAAKALLSGGAHPVLLHDDRLIPALLDSGRRGIPVSLEDARNYTCD 803

Query: 419  CCVSPMIVGKQMQFFGARANLAKTMLYAINGGV-------DEKLKMQVGPKSEPIKGDVL 471
             C  P+ VG     F     L   +  A+N G              +    S+     ++
Sbjct: 804  GCFEPVFVGASEFAFCTFP-LLDAVEMALNEGTLYSQAGPHFLRGSKKSFPSKNAT-QII 861

Query: 472  NYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVI----------- 520
             +++        +       ++ L   +    K      L  +    V            
Sbjct: 862  TFEQFQGIFVEHLQLQIPLLVSFLVGGYGNIWKMCPSPLLSVMMKGCVEACRDHTNGGTK 921

Query: 521  -RTMACGIAGLSVAADSLSAIKYAKVKP-----IRDEDGLAIDFEIEGE----------- 563
               +     G + A DSL AIK     P        +    +  +   +           
Sbjct: 922  YHDLGFMFVGAANAIDSLYAIKKLVYDPLTALTTLPDLLTCLKCDWGHDMKEYIFDARGG 981

Query: 564  --------------------YPQFGNN-DPRVDDLAVDLVERF----------------- 585
                                +P+FG+  +  + +L   + E                   
Sbjct: 982  SARKEAKASAFKHLREVATSFPKFGHGENAELKELGTWMFENVLTILRETFDNAKPGVKE 1041

Query: 586  -MKKIQKLHT----------YRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGA 634
              ++++K +               +    + T  + V YG  +  + DGRR+G P     
Sbjct: 1042 TFERLEKEYYIPGDPDNPERRFGFVVLPGIGTFEAYVGYGLNSAASADGRRSGQPIASDL 1101

Query: 635  NPMH-------GRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLA 687
            +P           D      +L             G+S    +    L   ++     L 
Sbjct: 1102 SPAPVPQDLPANPDSCDIYKALKC---WDIERINLGLSCGSEVDLMIL---EDFPLDKLT 1155

Query: 688  GLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQ 747
              +  Y   +  I G   + V   N E L  A +  + Y  + +R  G+   F +L  E 
Sbjct: 1156 EFLRRYADLDGPI-GSNVITVTCANPETLEKASKVTDAYELVRVRQGGWTEFFITLFPEH 1214

Query: 748  QQDVITRTFTQSM 760
            Q  +  R     M
Sbjct: 1215 QGQLRRRIDANKM 1227


>UniRef50_D0RZP3 Formate acetyltransferase n=1 Tax=Acinetobacter calcoaceticus RUH2202
            RepID=D0RZP3_ACICA
          Length = 1302

 Score =  398 bits (1022), Expect = e-109,   Method: Composition-based stats.
 Identities = 138/948 (14%), Positives = 270/948 (28%), Gaps = 216/948 (22%)

Query: 1    MSELNEKLATAWEGFTKGDWQN------EVNVRDFIQKNYTPYEGDES--------FLAG 46
            +++ +      W  F   DW          +    +  N++ Y  + +        F   
Sbjct: 353  LNDFSRLDKDNWNFFPGMDWNRFDRHYMNSSDNGLMYYNHSNYLFNMATGLNPHSEFFKP 412

Query: 47   ATEATTTLWDKVMEGVKLENR-THAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAP 105
             +    +L +      +          + +  V   I   D   I+ + E I+GL     
Sbjct: 413  PSNRILSLLENTFSLWQDNWYFNRKQEEIEQGVDYYIDEFD---ISDKPENIMGLSIMLR 469

Query: 106  LK------RALIPFGGIKMIEGSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDIL- 158
                      L                N E+ P       E +  +    + +   +I+ 
Sbjct: 470  KGWAIRLSLQLFSSENYGFRGRKILLKNGEMIPYSTGRECEGKVIYGSDTYRIMPDEIIV 529

Query: 159  --------------------RCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKL 198
                                  R  G L  L +A G G +I +Y++    G+  L ++  
Sbjct: 530  GAMPNLTLGEGRYVMKYLSEEERLQGFLRNLSEASGVGHVIPNYKKALDLGLAGLQQEI- 588

Query: 199  AQFTSLQADLENGVNLEQ--------------TIRLREEIAEQHRALGQ-----MKEMAA 239
            A+  S     E     E                 +L  ++A Q +   +     +  +  
Sbjct: 589  AKHASNAQTPEKKDFYEASRLALTGISEYFLNYSKLAFKVAGQMQKGQEFERDNLIAIGR 648

Query: 240  KYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITE 299
            +             +A+Q+ +  +       NG   +FGR    L  ++E+D     I  
Sbjct: 649  RMEKLSKDKPDTFIDAVQFIFTLHSCLHL--NGEPTAFGRMDQLLHPFLEKD----AIPP 702

Query: 300  QEAQEMVDHLVMKLRMVRFLR------------------TPEYDELFSGDPIWATESIGG 341
            +EAQE++D   +KL                         +  Y +  S        ++GG
Sbjct: 703  EEAQEIIDAFYIKLDEKVQQNRMFMEDHQPFGNLAMGGSSGPYPQGASLGQWIQQITVGG 762

Query: 342  MGLDG-------RTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAK-VSI 393
               DG       +    + +  F+     + P   P +++   + +P    + AA  +  
Sbjct: 763  TVADGEEDFSKTKPAYNEVTKLFIRASGRL-PLNAPCLSLRTRKDIPEEILEVAAHAILS 821

Query: 394  DTSSLQYENDDLMRPDFN-------------------------NDDYAIACCVSPMIVGK 428
              +     ND+ + P  +                           +YA   C  P   G+
Sbjct: 822  GGAHPILLNDEKLIPSLHQSGNGVGGDALTNLPNWNSKVDIRSAQNYACDGCYEPQFPGE 881

Query: 429  QMQFFGARANLAKTMLYAINGGV-------DEKLKMQVGPKSEPIKGDVLNYDEVMERMD 481
                 G   +  + +  A+N G               V   ++P    + +++E++E   
Sbjct: 882  NWFSLGG-FSTLQPLECALNQGKTISSAGQSYLFGQTVSLNTKP-ADQIDSFEELLELYK 939

Query: 482  HFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAG------------ 529
               + L ++      + +  +        L  L D  + +       G            
Sbjct: 940  QHFELLNRKAFNGQILGYGANTDICPSPILNVLMDDCLAKGQDFYSGGAKYNIYGPCYIS 999

Query: 530  LSVAADSLSAIKYAKVKP-----IRDEDGLAIDFEIEGE--------------------- 563
            LS   +SL AIK     P        E    +  +   +                     
Sbjct: 1000 LSNTINSLYAIKAMVFDPLTAVTTLPELLECLCCDWGYKMTEPFISNLAGHARIAAQADR 1059

Query: 564  ----------YPQFGNNDPRVDDLAVDLVERFMKK----------------------IQK 591
                       P++G  +P VD L  ++V+   +                          
Sbjct: 1060 YKRLREIALAQPRYGRGNPEVDKLGDEIVKMIAEISVKTFTHPWPQFAQSLKSLAECYGS 1119

Query: 592  LHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTS 651
                        V T  ++V  G   G + DGRR G       +P               
Sbjct: 1120 KEHPFGIQIQPGVGTFENHVEMGAWNGASADGRRLGTTVASDLSPSPS-----PADLAID 1174

Query: 652  VAKLPFAYAKD-----GISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHL 706
              K+ F+ A       G +      P      ++     L  ++  +    +       L
Sbjct: 1175 HQKVEFSRALQGFEGIGTNLMADGAPTDFNIGEDFGVQELVAILKQF----SQGSSSNIL 1230

Query: 707  NVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITR 754
             + V + E    A+ +PE+Y  L +R  G++  F S+    Q+    R
Sbjct: 1231 TITVADPETFAQAVTSPEQYNLLRVRTGGWSNFFTSVFPTIQEQHQRR 1278


>UniRef50_C5V5J7 Formate C-acetyltransferase n=1 Tax=Gallionella ferruginea ES-2
           RepID=C5V5J7_9PROT
          Length = 962

 Score =  397 bits (1019), Expect = e-108,   Method: Composition-based stats.
 Identities = 126/883 (14%), Positives = 242/883 (27%), Gaps = 201/883 (22%)

Query: 63  KLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFG-GIKMIEG 121
             E ++ +P          +  H    + +  + + G  T + +   +     G  +   
Sbjct: 75  TPEAQSLSPEVRRARAVRHVFEHKKA-LVRASDLLPGQTTTSFVGPVIYMDTIGYCIWPE 133

Query: 122 SCKAYNRELDPM----------IKKIFTEYRK------------THNQGVFDVY------ 153
                 R  +P            K+IF  +               ++ G +         
Sbjct: 134 LNTVETRSQNPFKISSDVAKRLNKEIFPFWLDQQRPVQEAARAAAYDTGDYPFMDEVNGD 193

Query: 154 ------------TPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQF 201
                       TP      +         +      + D+ R+  YG+D L        
Sbjct: 194 SIDPALKKMAGETPKCQELMERVAFYLSDKSTCVSHTVPDWDRLLKYGLDGLAAQMRFDL 253

Query: 202 TSLQADLENGVNL------EQTIRLREEIAEQHRALGQMKEMAAKYGYDISGPATNAQEA 255
               ++             E  +     +AE   A G   E+A       + PA    EA
Sbjct: 254 AVANSEPARQFLAGVIDTFEGAMTYANHLAEAAEAAGN-SELARICRKVPAQPADTLHEA 312

Query: 256 IQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIER-------DLKAGKITEQEAQEMVDH 308
           +   +  Y   ++      +S GR    L+ Y  +       D      T   A E++ H
Sbjct: 313 LSAIWICYHLLLQENTNFGLSLGRLDQLLNPYYFKEWQKLGSDEARASYTR-HAVELICH 371

Query: 309 LVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMG-LDGR--TLVTKNSFRFLNTLYTMG 365
             ++      L T   + LF+G       ++GG    +G+    V   ++  L     + 
Sbjct: 372 FFLRCSDHVPLSTSGSETLFAGSGSNQALTVGGTRYENGQVVDAVNDMTYIILKAT-ELL 430

Query: 366 PSPEPNMTILWSEK---------------LPLNFKKFAAKVSIDTSSLQYENDDLMRPDF 410
              +PN+   +                  +    K+         ++     D  +    
Sbjct: 431 SIRDPNVHARYHADVHRRDADGNSLSRDAMDDYLKRICQVNIATRATPALHGDIPVIRSM 490

Query: 411 -----------------NNDDYAIACCVSPMIVGKQMQFFGAR-ANLAKTMLYAINGGVD 452
                            +  DYA   C+     GK     G+    L   +  AI GG  
Sbjct: 491 AAYYADHKGVSDEEAMQDACDYASIGCIEQNAPGKHYGNSGSTLLVLPAVLELAIFGGKH 550

Query: 453 EKLKMQVGPKSEPIKGD----------VLNYDEVMERMDHFMDWLAKQYITALNIIHYMH 502
                  G   +   G           +   +E +      ++ +AK  +   N +  + 
Sbjct: 551 RSDGT-GGTDPDLFNGQPRYTSVPLLGMTCMEEFVSAFGFQLNEMAKHAVQNNNYLGRVM 609

Query: 503 DKYSYEASLMALH-------------------DRDVIRTMACGIAGLSVAADSLSAIKYA 543
            K      L  L                          +    I GL+   D+   +   
Sbjct: 610 AKERASPFLSGLFTGPVNLPGEQGAKFRDVAAGGAKYNSAGVAIIGLADVIDTFCILDEL 669

Query: 544 KV--KPIRDEDGLAIDFEI--------EGEYP---------------------------- 565
               K    E   A+  +         + ++P                            
Sbjct: 670 VFSGKVSAAELLSAMGSDFSVAKHASEQHDWPHYLEKMRRWLHPDATVPLPALSAERLAE 729

Query: 566 ---------QFG--------NNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTIT 608
                     +G         ++      +  L     +      T+R         ++T
Sbjct: 730 ICTAIKHTAHYGAGVAQNGIFDNSLAVTYSRRLTRMIHEVFYAYRTHRGGRYLTGYWSMT 789

Query: 609 SNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLT-----SVAKLPFAYAKDG 663
           ++  +G  T  TP+ RRAG  F  G  P  G  ++     +      SVA +     K+G
Sbjct: 790 NHAGFGMLTQATPNLRRAGQAFASGITPCPGIVKRDGTPVMALDHMLSVAAVDSDAVKNG 849

Query: 664 ISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAME-- 721
            +Y  S+       +        A  M  +  +      G  + + V +   L+ A +  
Sbjct: 850 YTYNLSLTTRG-AAERSADIELFARYMRAFTDNN-----GVLVQLCVSSIADLVAADKAA 903

Query: 722 ---------NPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRT 755
                        Y  L IRV+GY+  F +L+ + + ++I R 
Sbjct: 904 AMEGAGAFEALAPYKDLMIRVAGYSAYFVTLSAQMRTEIIARA 946


>UniRef50_Q2HBR9 Putative uncharacterized protein n=1 Tax=Chaetomium globosum
            RepID=Q2HBR9_CHAGB
          Length = 1229

 Score =  392 bits (1006), Expect = e-107,   Method: Composition-based stats.
 Identities = 111/758 (14%), Positives = 224/758 (29%), Gaps = 147/758 (19%)

Query: 129  ELDPMIKKIFTEYRKTHNQGVFDVYT-PDILRCRKSGVLTGLPDAYGRGRIIGDYRRVAL 187
            E   +I  +  ++     + V    +  + +     G L    +    G I+  Y  +  
Sbjct: 441  EAKELIVGVIPDFTLGRGKEVVPYLSDEETMAAWLKGSL---NEWSAMGHIVPGYDLLVR 497

Query: 188  YGIDYLMKDKLAQFTSLQADLENGV---------------NLEQTIRLREEIA-----EQ 227
             G+  ++ D   +   +                        L    ++ +  A       
Sbjct: 498  DGLKKMITDIKDKLAKVSDPASATASFYESCIISLEGVQGYLRNWAKIAQRAAIAAGMTA 557

Query: 228  HRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVY 287
               +  MK++ A+          + Q+A+Q  Y  +        G    FGR    L  Y
Sbjct: 558  PDDVANMKDVEARMNRLADDAPESFQDAVQLIYSFHCCLHLV--GELTPFGRLDQILYPY 615

Query: 288  IERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELF-----------------SG 330
            + +    G  T + AQE++D L +K+    F+      +                    G
Sbjct: 616  LSK---GGGTTLEHAQEIIDCLWVKIGENAFVNRAFIYDYVTYGTTAVCGLGGNFPQGGG 672

Query: 331  DPIW-ATESIGGMGLDGRTLV-----TKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNF 384
               W    ++GG      +          +   L     + P   P +++   + +P  +
Sbjct: 673  INQWVQQITVGGYKAT-DSATPECGANAVTMLCLKAARRI-PVNAPTLSLRVHKDIPHEY 730

Query: 385  KKFAAK-VSIDTSSLQYENDDLMRPDFN------------NDDYAIACCVSPMIVGKQMQ 431
               AAK +    +     NDD + P               + DYA   C  PM+ G    
Sbjct: 731  LDEAAKGILSGGAQPILYNDDKLCPALKDSATANVVDLKWSRDYAADGCYEPMLAGASEF 790

Query: 432  FFGARANLAKTMLYAINGGV-------DEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFM 484
             F         +   +N G        ++   ++   +S+P K +  +++++ +     +
Sbjct: 791  TFN-NVAPLLALEQTLNEGSTYGEAGPEQLRGLKQTFRSKPAK-EFKSFEDLKDTFVKQL 848

Query: 485  DWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMAC------------GIAGLSV 532
            +WL  Q    +   +           L  L    V +                   G+S 
Sbjct: 849  EWLVVQCYNTMLDGYGNLANVCPSPLLSVLIQGCVEKGRDLTNGGSKFHIMAPLCVGMSN 908

Query: 533  AADSLSAIKYAKVKP-----IRDEDGLAIDFEIEGEY----------------------- 564
              DSL AI+              E    +  +                            
Sbjct: 909  TIDSLYAIQKLVFDDETARVTLQELVKCLICDWGHNMIEPYENQLSGTADASERGLRYSE 968

Query: 565  --------PQFGNNDPRVDDLAVDLVERFMKKIQK-------------------LHTYRD 597
                    P++G+ D  V+ L   LV+  +    K                        +
Sbjct: 969  LRNAALALPKWGSGDEEVNKLGDWLVQTCVDLCVKAIRHPNATIKAHLDNIKKTYGEDFE 1028

Query: 598  AIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPF 657
             I    + T    V  G   G + DGRR+G P     +P+       A  +  ++ +   
Sbjct: 1029 FIICPGIGTFEGYVGDGIPCGASADGRRSGMPIASDLSPVPAAQDLPASPAFRNIYQAME 1088

Query: 658  AYAKDGISYTF-SIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREML 716
            +   + I +   +  P  +   +      L   +  Y    A   G   + +   + +  
Sbjct: 1089 STKYNSIEHGLSNAAPVDMNIPESFPLPELQKFVKKY---AAGEVGSNLITLTCADLDTY 1145

Query: 717  LDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITR 754
              ++ +PEKY  + +R+ G+   + ++    Q     R
Sbjct: 1146 QKSVRDPEKYNLVRVRMGGWTEFYATMFPAHQDQQQRR 1183


>UniRef50_A7VW43 Putative uncharacterized protein n=1 Tax=Clostridium leptum DSM 753
           RepID=A7VW43_9CLOT
          Length = 737

 Score =  386 bits (991), Expect = e-105,   Method: Composition-based stats.
 Identities = 120/691 (17%), Positives = 240/691 (34%), Gaps = 93/691 (13%)

Query: 119 IEGSCKAYNRELDPMIKKIFTEYRKTHNQGV-FDVYTPDILRCRKSGV-LTGLPDAYGRG 176
           ++       R  D       T+YRKT    + +  +  D          +       G G
Sbjct: 80  VDPIEILCGRWGDQ-----LTKYRKTQGNYMDYRNFPEDRFPYDHLKPGIDLYGIDSGIG 134

Query: 177 ---RIIGDYRRVALYGIDYL-------------MKDKLAQFTSLQ-ADLENGVNLEQTIR 219
                  D+      G                  K+K   + + +   L     +++ I 
Sbjct: 135 SDSHFNSDFNIGIALGWGGFLEKIRKYREIHKGDKEKQEFYDAEEKVVLAIQKWIQKHID 194

Query: 220 LREEI---AEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWT-YFGYLAAVKSQNGAAM 275
             EE+    ++      ++EM A     IS       EA Q+  +F  ++ +  ++GA  
Sbjct: 195 RIEELLKTEDRPEIRATLEEMLACNKNVISKKPETFLEACQYLAWFATVSRIYDRDGAGC 254

Query: 276 SFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWA 335
                   L  + ++D+++G I + +A+ ++  L++          P Y +         
Sbjct: 255 W---LDQLLYPFYKKDMESGLIDKDKARFILADLLI--------IDPHYYQ--------- 294

Query: 336 TESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSID- 394
              +GG  L+G  +  + S+  L   + +  S   N+T+   + +   F K A     + 
Sbjct: 295 ---LGGCDLEGNDMTNELSWLILEAAHELNTSA--NLTVRVHDNMDPAFFKKAVSYVFND 349

Query: 395 -TSSLQYENDDLM--------RPDFNNDDYAIACCVSPMIVGKQMQFFGA-RANLAKTML 444
             +  ++     M          + +  +     C    + GK+       + N  K   
Sbjct: 350 RNAWPRFSGHKGMMNYAKNQGVSEKDALERQAVGCGWSAVPGKEFCMNDVIKINCVKVFE 409

Query: 445 YAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDK 504
            A    +          K +        YD     +   +  +A          H    +
Sbjct: 410 VAFQEMMLAYHDAAPTDKEKYAPSLERLYDIYRAHLKRAVKVIADCVEFYNQYQHITMPE 469

Query: 505 YSYEASLMALHDR------DVI-RTMACGIAGLSVAADSLSAIKYA---KVKPIRDEDGL 554
                 +    +            T+ C   GL   ADS +AI+     + K   +E   
Sbjct: 470 LVMNLQMYHTLEEGKNISQCAEIYTLCCDGVGLGTLADSFAAIEQRIVREKKLTFEELEE 529

Query: 555 AIDFEIEGEYP---------QFGNNDPRV-DDLAVDLVERFMKKIQKLHTYRDAIPTQSV 604
            +     G+           ++      + D  A  L   F + ++              
Sbjct: 530 TLRNNFAGDERTRLMLSQSERYCQGGDSLGDQWAQRLTRDFAEIVKAQPVAGGKQLVPGW 589

Query: 605 LTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKG-AVASLTSVAKLPFAYAKDG 663
            + +  + +G++ G TP+GR+AGA    GANP  G  + G A A  T +A     Y  + 
Sbjct: 590 FSWSKTIHFGRQVGATPNGRKAGASVTHGANPTPGFRKDGAATAQATGIALCQPGY-GNT 648

Query: 664 ISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENP 723
                   P      +E     +A L+  +        GG  +NVNV+++++L++A ++P
Sbjct: 649 APLQIEFDPKL--SAEEGGIDRVAKLLKTHIDM-----GGTLINVNVLDKDVLMEAHKDP 701

Query: 724 EKYPQLTIRVSGYAVRFNSLTKEQQQDVITR 754
           + +P+L +RV+G+   F +L+++ +Q V+ R
Sbjct: 702 KSHPELVVRVTGFTAYFCTLSEDFRQLVVDR 732


>UniRef50_O26446 Formate acetyltransferase 2 n=1 Tax=Methanothermobacter
           thermautotrophicus str. Delta H RepID=O26446_METTH
          Length = 642

 Score =  383 bits (984), Expect = e-104,   Method: Composition-based stats.
 Identities = 120/660 (18%), Positives = 221/660 (33%), Gaps = 111/660 (16%)

Query: 134 IKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGR-GRIIGDYRRVALYGIDY 192
           ++K+  + R   N G    Y+ D      +G+     + Y R G +  DY  +   G++ 
Sbjct: 53  LEKVCRDSRIHFNPGDRFFYSID------TGIHVLETEGYRRLGNLTPDYGLLVERGLEG 106

Query: 193 LMKDKLAQFTSLQADLENGVNLEQTIRLREEIAEQHRALGQMKEMAAKYGYDISGPATNA 252
           + ++ +        D+     L       E  AE         E+A K       PA   
Sbjct: 107 I-EEMIEDEPGGYPDILRRA-LGAVKLYLERCAEHSP------EIADKLRRVPLKPAETL 158

Query: 253 QEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMK 312
            EA+Q   F             +  GR  + L  Y E          +E++E++   ++ 
Sbjct: 159 GEALQSILFMNSLIWM-YGHPLIGLGRLDSILKEYHE--------DPEESRELIRDFILS 209

Query: 313 LRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNM 372
           +      ++                 +GG            +  FL  +  +   P+P +
Sbjct: 210 VSSCYEFKSNVLPG-----DTGQVIVLGG-------EYNDLTRIFLEVMLEL-RIPDPKV 256

Query: 373 TILWSEKLPLNFKKFAAKVSI-DTSSLQYENDDLMRPDF-------NNDDYAIACCVSPM 424
            +  + + P +  + + +          + NDD++           +  +YA + C  P+
Sbjct: 257 VLRVNSRTPDDVWELSYRCLREGLGYPLFSNDDVIVDALSQYYSRSDALEYATSACWEPL 316

Query: 425 IVGKQ-MQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHF 483
           I G+   Q   A  NL + +  A++G   E                   + E++ER    
Sbjct: 317 IPGRSSDQNNLANLNLLEPLEDALHGFRGE-------------------FSELLERYRQE 357

Query: 484 MDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMAC-----------GIAGLSV 532
           +       +  +  +     +      L  L    +  +                 G+  
Sbjct: 358 LHRYIDDVMENVESV-----RNEPSPLLSLLFPDCIRNSRDICDGAGYSINGVLTVGMGN 412

Query: 533 AADSLSAIKYAKVKPIRD-----EDGLAIDFE--------IEGEYPQFGNNDPRVDDLAV 579
             +SL  I+              ED L  DF         +E   P +G ++  V +L  
Sbjct: 413 LINSLLNIRRLCYDEKTMNIAEVEDVLRDDFRSAEALRVGLELISPGYGMDEDEVVELTN 472

Query: 580 DLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHG 639
            +++    K+               L+    +  G+ TG + DGR AG P G   +P+  
Sbjct: 473 TIIQMLHDKL-------GGRYKFG-LSSPVYITLGESTGASFDGRHAGEPLGVHISPLKF 524

Query: 640 RDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEAS 699
            D       L   A L +  A +G      +    L +           L+         
Sbjct: 525 TDGMSYTEVLNFAAALDYLKAFNGGVVDIMVDRPFLDRAGN----EFMALIRT-----GL 575

Query: 700 IEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQS 759
             G   L VNV++ E+LL A +NPE YP L +RV G++  F  L +E ++ ++ R    S
Sbjct: 576 RRGVMQLQVNVLDPEVLLRARDNPELYPDLIVRVWGFSAYFRDLPEEYRELIVRRALEYS 635


>UniRef50_C6IIV1 Formate acetyltransferase 2 n=3 Tax=Bacteria RepID=C6IIV1_9BACE
          Length = 714

 Score =  378 bits (972), Expect = e-103,   Method: Composition-based stats.
 Identities = 121/687 (17%), Positives = 233/687 (33%), Gaps = 95/687 (13%)

Query: 119 IEGSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRI 178
           I+       R +  M K    ++        +D    +I +     ++ G+ D       
Sbjct: 76  IDADDAFAGRWMYFMSKMRPNKWNP---DYSYDFLKENIKK---YDLICGIGDDA---HF 126

Query: 179 IGDYRRVALYGIDYLMKDKL---------AQFTSLQADLENGVNLEQTIRLREEIAEQHR 229
             DY      G + L+K             Q       L    +++  I+   + A +  
Sbjct: 127 APDYEIGVKLGWNGLIKKIEHYQSMHHSEEQQHFYSLHLRVIRSVQGWIQRHIDQAYRMA 186

Query: 230 ALGQ-------MKEMAAKYGYDISGPATNAQEAIQWTYFGYLA-AVKSQNGAAMSFGRTS 281
           A          + E+A      I+   T  +EA QW  + +LA    +++GA    G+  
Sbjct: 187 ASATDDCSKNNLLEIAKVNESIINDAPTTLREACQWIIWYHLASRTYNRDGAG---GQID 243

Query: 282 TFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGG 341
           T L  + E+DL  G+I ++ A   +   ++                           +GG
Sbjct: 244 TLLAPFYEKDLAEGRIDKETAVYYLACFLL--------------------NDPVYWQLGG 283

Query: 342 MGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAK--VSIDTSSLQ 399
               G+   +  SF  L     +  S   N+T+   + L  +  + + +  V       +
Sbjct: 284 PDESGKDQTSPLSFLILEAADKINTSL--NLTVRVFDGLNKDLFRKSVEYLVKNKNGWPR 341

Query: 400 YENDDLMRPDFN--------NDDYAIACCVSPMIVGKQMQFFG-ARANLAKTMLYA---- 446
           +  D  +   F                 C    + G +       + N+AK    +    
Sbjct: 342 FSGDKALVEGFMKNGFSAQLARRRIAVGCNWMSLPGLEYTMNDLVKINMAKVFEVSYTEM 401

Query: 447 INGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYS 506
           +N   D          +E +   V    + +     F  +          ++  +     
Sbjct: 402 MNEQKDHSTSRLWMLFNEHLAKAVQTSADGIRHHLKFQKY------NEPELLLNLLSHGP 455

Query: 507 YEASLMALHDRDVIRTMACGIAGLSVAADSLSAIKY---AKVKPIRDEDGLAIDFEIEG- 562
            E              +A   AGL+  ADS +A++     + K   +     +     G 
Sbjct: 456 LEKGKDVSDGGAEYYNLAIDGAGLATVADSFAALEQRIELENKLSWNTLTEYLRNNFSGD 515

Query: 563 ----------EYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTY-RDAIPTQSVLTITSNV 611
                        ++G  +   +  A+ + E F + ++      +  I      +  + V
Sbjct: 516 GGCRIRHLLKNSEKYGAAESLGEKWAIRIKETFTELVRLQSEPDKRRIFIPGFFSWANTV 575

Query: 612 VYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIV 671
            +G+  G TPDGR A  P   GANP  G  + GA  SL ++         +     + + 
Sbjct: 576 GFGQSVGATPDGRLAQTPISHGANPTPGFVKDGASLSLATIIAKIQPGYGNTAPMQWELD 635

Query: 672 PNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTI 731
           P     D       +  ++  +F       GG  +NVN+MN++ +L A ++P  YP+L +
Sbjct: 636 PTFANMD---NIELIMSIIRAHFDL-----GGTLINVNIMNKDTVLAAHKDPAGYPELVV 687

Query: 732 RVSGYAVRFNSLTKEQQQDVITRTFTQ 758
           RV+G+   F+ L+ + +Q V+ R    
Sbjct: 688 RVTGFTAYFSMLSPQFRQLVVDRILES 714


>UniRef50_Q24T37 Putative pyruvate-formate lyase n=1 Tax=Desulfitobacterium
           hafniense Y51 RepID=Q24T37_DESHY
          Length = 626

 Score =  378 bits (970), Expect = e-103,   Method: Composition-based stats.
 Identities = 105/617 (17%), Positives = 208/617 (33%), Gaps = 72/617 (11%)

Query: 175 RGRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLENGVNLEQTIRLREEIAEQHRALGQM 234
            G +  DY      G++    +        + ++     +E  +R    I  Q R +   
Sbjct: 43  YGNLSPDYETFLHGGLN----ELRICDPKTRFEIHRNRIVEIILRYAGRIEAQLREMETT 98

Query: 235 KEM--AAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDL 292
             +  A  +      PA + +EA+Q   F      +  N   +  G     L  + E+ L
Sbjct: 99  TAVLRAKWFSRFADYPAESFEEALQRILFVNQLMWQ-TNHRLVGLGHWDALLGGFYEKGL 157

Query: 293 KAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTK 352
           +   +T ++A  ++    +++  + +        L  GD       +G    +G  + T 
Sbjct: 158 QNRTLTLEDAFSLL-CSALRILHIDY---KFKSNLVLGD-TGQIIVVGASNQNGDYVGTG 212

Query: 353 NSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKV-SIDTSSLQYENDDLMRPDF- 410
            +   ++ +  +   P+P + +  ++K+P +  + A    +    S    NDD++ P   
Sbjct: 213 LTDLIISAVKELAQ-PDPKVLLRVNKKMPDDLWETALDCMASGCGSPLLSNDDVIIPHLV 271

Query: 411 -------NNDDYAIACCVSPMIVGKQMQFFGAR-ANLAKTMLYAINGGVDEKLKMQVGPK 462
                  +   Y  + C  P+I GK          N  K     +N              
Sbjct: 272 SFGVTPEDACSYITSACWEPLIAGKDSSLNNVTSLNFMK----GLNNVFQR--------- 318

Query: 463 SEPIKGDVLNYDEVMERMDHFMDW-------LAKQYITALNIIHYMHDKYSYEASLMALH 515
                  + +Y+E+  R   F+         +  Q     + +  +  K   E+     H
Sbjct: 319 --DNLQKINSYEELKARYRLFLAHNITAVKRVVSQQRFQYDPVLSLFMKGCSESGKDVAH 376

Query: 516 DRDVIRTMACGIAGLSVAADSLSAIKYAKVK---PIRDEDGLAIDFEIEGEYP------- 565
              V   +     GLS   ++L  +K    +      +E    ++   E   P       
Sbjct: 377 GGAVYHDIGITTVGLSNVVNALLNLKEHVFERHTYTLEEVQSILNDNFENHEPLRKQLSS 436

Query: 566 ---QFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPD 622
               +G +D  V DL  +L+    ++     TY         L+  + +   +    + D
Sbjct: 437 REIAYGVDDSEVIDLTNELIRFVSEQTSDFRTYLGGRLKFG-LSAPAYIDAARDFPASFD 495

Query: 623 GRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAK-DGISYTFSIVPNALGKDDEV 681
           GR+   PF    +             +  VA L     + +G        PN +      
Sbjct: 496 GRKMDEPFAVHIS---NEKISAYTTIINFVAALDLGGNRFNGNVIDLMATPNFIHD---- 548

Query: 682 RKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFN 741
            K  L  L+       A+  G   + +NV N + L++A + P  +P L +RV G++    
Sbjct: 549 NKEKLIALLR-----IATDIGFFQMQMNVFNSKTLIEAKKRPSDFPNLIVRVWGFSAYMI 603

Query: 742 SLTKEQQQDVITRTFTQ 758
            L +E +  +I R    
Sbjct: 604 DLPEEYKDVLIMRALEN 620


>UniRef50_C7XCZ5 Formate acetyltransferase 2 n=2 Tax=Bacteria RepID=C7XCZ5_9PORP
          Length = 670

 Score =  366 bits (941), Expect = 1e-99,   Method: Composition-based stats.
 Identities = 111/617 (17%), Positives = 217/617 (35%), Gaps = 85/617 (13%)

Query: 178 IIGDYRRVALYGIDYLMKDKLAQFTSLQADLENGVNLEQTIR-LREEIAEQHRALGQMKE 236
           I  DY  +    +  +M+    +       +     + + I      I+EQ     + + 
Sbjct: 94  ITPDYALIINSDLREIMRSLPERSGDNSDFIGTLHIVTKAIEDKARAISEQRYEDVRYEA 153

Query: 237 MAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGK 296
           MA +    +     +  EAIQ   F      +  +   +  GR    L  Y ++D++A +
Sbjct: 154 MAKRLPDLLYRDCQSLVEAIQKVLFYNGLLWQVGHRH-VGLGRMDLVLYPYYKKDVEANR 212

Query: 297 ITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFR 356
           +  ++A+ ++  + + L     +++                 +GG+  +G+    + +  
Sbjct: 213 LNYEQAKGLLKEMCLLLGKDSPMKSLNLIG-----DSGQYIILGGVDKNGKNTDNELTRM 267

Query: 357 FLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSI-DTSSLQYENDDLMRPDF----- 410
           FL     +   P+P +    +E+ P++  K + +       S  + N+ L+  +      
Sbjct: 268 FLELFEEL-RIPDPKLIFRVNEETPMDTWKRSIRCLANGCGSPLFMNETLIMENMVKFGY 326

Query: 411 NNDDYAIAC---CVSPMIVGKQMQFFGARANLAKT--MLYAINGGVDEKLKMQVGPKSEP 465
            N+D        C  P+I+GK         ++     +  A+    DE            
Sbjct: 327 RNEDVWNVGTSACWEPLIIGKSSDQNNPFISILACNALKKALTEMEDEL----------- 375

Query: 466 IKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMAC 525
                 +Y  +++ +   +    +  +        +   Y Y   +   ++  +      
Sbjct: 376 ------DYGGLLQLVKRNLAEETRSVV--------VDKDYDYSPIMSLFNESCIRSGKDF 421

Query: 526 ------------GIAGLSVAADSLSAIKYAKVKPIRDEDG---LAIDFEIEGEYP----- 565
                        + GL    +SL  IK    +      G     +  + E         
Sbjct: 422 AHQGSDYMYQGAQLLGLPNLVNSLLNIKKYVYEQGLVSLGICREIVQTDYENHLDIKQLF 481

Query: 566 ------QFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGN 619
                 +FG  D  V  L+ +L+    + I KL    +    +  L+  S +  GK    
Sbjct: 482 KSANDKKFGLCDEYVLRLSQELIGTVSETIGKLTA--NGYNVKFGLSSPSYISRGKVASA 539

Query: 620 TPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFA-YAKDGISYTFSIVPNALGKD 678
           T DGR AG PF    +P+           L   + L +     +G    + I P  L   
Sbjct: 540 TLDGRNAGEPFAVHISPLSSTID--IAEVLDFASSLSYPVNCLNGNVVDYVIPPVYLNNS 597

Query: 679 DEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAV 738
           D      L  ++   F      +G   L +NV +R  L+DA  +PEKYP L +RV G++ 
Sbjct: 598 D-----KLVPILRDAFK-----KGLYQLQLNVYDRATLIDAKLHPEKYPTLVVRVWGFSA 647

Query: 739 RFNSLTKEQQQDVITRT 755
            FN L +E + ++I R 
Sbjct: 648 YFNDLPEEYKDNLIARA 664


>UniRef50_C0A3H6 Formate C-acetyltransferase n=1 Tax=Opitutaceae bacterium TAV2
           RepID=C0A3H6_9BACT
          Length = 765

 Score =  351 bits (901), Expect = 6e-95,   Method: Composition-based stats.
 Identities = 115/640 (17%), Positives = 223/640 (34%), Gaps = 101/640 (15%)

Query: 175 RGRIIGDYRRVALYGIDYLMKDKL--------AQFTSLQADLENGVNLEQTIRLR----- 221
                 D       G   +++            +    + +    + ++  IR       
Sbjct: 166 DAHYACDLAMGLRLGWGGILEKLRHYRALNGHDKAVFYECEERTALAIQGWIRRTIAEVD 225

Query: 222 EEIAEQ--HRALGQMKEMAAKYGYDISGPATNAQEAIQWT-YFGYLAAVKSQNGAAMSFG 278
            ++A +   R    ++EM A   + + G     +EA QW  +F       ++ GA    G
Sbjct: 226 RQLATEADPRLRENLREMKAVNEWVVEGAPRTLREACQWLAWFVLAKRTYNRCGAG---G 282

Query: 279 RTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATES 338
           +    L  Y ERD  AG I ++EA   +  L++                           
Sbjct: 283 QLDELLRPYYERDAAAGLIDDEEAAFTIACLLL--------------------VDAQYYQ 322

Query: 339 IGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVS--IDTS 396
           + G G DGR + ++ S   L+    M      N+TI   + L     +    +       
Sbjct: 323 LAGPGPDGRDMTSRISHIILDAAELMD--GPCNLTIRVHDDLDPELFRRGVYLLFHHKKG 380

Query: 397 SLQYENDDLMRPDFNNDDYA--------IACCVSPMIVGKQMQFFGA-RANLAKTMLYAI 447
             ++  D  +   F    Y+           C    + G +       + NLAK    A 
Sbjct: 381 WPRFSGDKALVAGFMRAGYSEELARQRIAVGCNWMSLPGLEYTLNDVVKVNLAKVFEVA- 439

Query: 448 NGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALN--IIHYMHDK- 504
                     +    +          + + E     +    ++     +  + H  H++ 
Sbjct: 440 ---------WKEMFAAANDGTAAPGLERLWEIYLAHLRVAVEKTADGNHFHMCHQTHNEP 490

Query: 505 ---------YSYEASLMALHDRDVIRTMACGIAGLSVAADSLSAIKYAKVKPIRDEDGLA 555
                       E  L           +A   AG++V ADS +A++              
Sbjct: 491 ELVTNLLCHGPLEKGLDMAAGGARYCNLAIDGAGIAVVADSFAALEQRVADEGCLTWAE- 549

Query: 556 IDFEIEGEYP---------------QFGNN-DPRVDDLAVDLVERFMKKIQKL-HTYRDA 598
           +++ IE  +P               ++G     R +  AV +   +   ++     Y D 
Sbjct: 550 VNWHIEKNFPDIEGERVRLMLQSSERYGQATGNRAERWAVRITGTWSGMVRDQNRRYPDY 609

Query: 599 IPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGA-VASLTSVAKLPF 657
                + +  + + +G+    TP+GRRAG P   GANP+ G  + GA  A + ++A +  
Sbjct: 610 NFIPGLFSWANTIEFGEAVSATPNGRRAGQPINHGANPLPGFRKDGAVTALVNAIAAVQP 669

Query: 658 AYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLL 717
            Y  +       + P+     + + K  +  L+   F      +G   LN+N+++ E +L
Sbjct: 670 GY-GNTAPVQLELDPSIAESPEAIEK--ITALIKTMFD-----QGCTLLNINLIDEERVL 721

Query: 718 DAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFT 757
           +A ++P K+P L +RV+G+   F  L+ + +Q V+ R  +
Sbjct: 722 EAHKDPSKFPDLIVRVTGFTSYFAMLSPQFRQLVVDRILS 761


>UniRef50_A3RV69 Formate acetyltransferase n=5 Tax=Ralstonia solanacearum
            RepID=A3RV69_RALSO
          Length = 1352

 Score =  338 bits (867), Expect = 6e-91,   Method: Composition-based stats.
 Identities = 114/752 (15%), Positives = 211/752 (28%), Gaps = 187/752 (24%)

Query: 169  LPDAYGRGRIIGDYRRVALYGIDYL---MKDKLAQFTSLQADLENGV------------- 212
            L    G G ++  Y  +  YGI  L   + +      +                      
Sbjct: 618  LGPTSGVGHVVPGYEALLAYGISGLSGRIDEAQQALAATDPQRAEEAKSFYAGARLALRG 677

Query: 213  ---NLEQTIRLREEIA-----EQHRALGQMKEMAAKYGYDISGP-ATNAQEAIQWTYFGY 263
                L+   +   E A     +Q      ++ M  +     SG       EA+Q     +
Sbjct: 678  LAEYLDGLAQTAHETAQALPQDQEIERKNLEAMQHRLQRLASGAAPETVLEALQLVLACH 737

Query: 264  LAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFL---- 319
                    G  ++ GR    +  + E+      + E + QE +D   +KL     L    
Sbjct: 738  ATLHL--CGEPVAVGRLDRLIRPFQEKS----PLDEAQLQEAIDCFWLKLGEKALLNRIF 791

Query: 320  --------------RTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMG 365
                          R   Y +  S +      ++GGM  DG    +  +   L     + 
Sbjct: 792  IDDHQELGNLAMGNRAGPYPKGQSVNQWIQQITVGGMNADGSWEYSDVTLACLRASSRL- 850

Query: 366  PSPEPNMTILWSEKLP----LNFKKFAAK-VSIDTSSLQYENDDLMRPDF---------- 410
            P   P +++  S+ +P          AA+      +S    NDD + P            
Sbjct: 851  PFNAPVLSLRVSKDMPSVWRKRLLAEAARGQLSGGASPILLNDDKIIPALSSSGIGIGPR 910

Query: 411  ----------------NNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEK 454
                            +  DYA   C  P  VG      G    L + +  A++ G   +
Sbjct: 911  ANADEAARWNSTVRREDAHDYACDGCYEPQFVGANWFHLGG-VTLLQMLEVALDQGRQMQ 969

Query: 455  L-------KMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSY 507
                       V  +S P    + +Y E+       ++W   + +          D    
Sbjct: 970  SAGPIDLLGKNVSFRS-PPATAIASYAELEGLFFKHLEWTYARQMEGTVADFGRMDGVCP 1028

Query: 508  EASLMALHDRDVIRTMACGIAG------------LSVAADSLSAIKYAKVKP-----IRD 550
               L       + +       G            L+   ++L AI+              
Sbjct: 1029 SPLLNLFIHDCLDKGRDIYAGGARYNVFGPCFTSLANTINALWAIRVMCFDQATAITTLS 1088

Query: 551  EDGLAIDFEIEGE----------------------------------YPQFGNNDPRVD- 575
            E   A+                                          P++G  +  +D 
Sbjct: 1089 ELVQALLCNWGENVIDPLVHPTVLAGDATRASQAATRFRQLRSIALSLPRWGRGNADIDT 1148

Query: 576  ----------DLAVDLV--------ERFMKKIQKL----HTYRDAIPTQSVLTITSNVVY 613
                      ++AV ++        +++ +K        H +        V T  S V  
Sbjct: 1149 FGNTICQRVAEIAVRVMAQPRDGLADQYRRKAMAYGTPAHPFGGFCMQPGVGTFASYVEQ 1208

Query: 614  GKKTGNTPDGRRAGAPFGPGANPMHG-----------RDQKGAVASLTSVAKLPFAYAKD 662
            G     + DGR +G P G   +P              +   G  A L  +         +
Sbjct: 1209 GLGCSASADGRLSGQPLGTDMSPAPSPLDLPATDASQQRVDGVRA-LKGIRATDAFGFAN 1267

Query: 663  GISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMEN 722
            G     +I        + + ++ L  ++D +       +G   L V   ++   L A  +
Sbjct: 1268 GAPVDLNID-------EHMGESRLVEILDAFVD----GDGSNILTVTTADQATFLAAANS 1316

Query: 723  PEKYPQLTIRVSGYAVRFNSLTKEQQQDVITR 754
            PE +  L +R+ G+   F ++    Q+    R
Sbjct: 1317 PESFDLLRVRMGGWTEMFVAMHATHQKVHPRR 1348


>UniRef50_Q2C4S5 Formate acetyltransferase n=7 Tax=Gammaproteobacteria
           RepID=Q2C4S5_9GAMM
          Length = 280

 Score =  309 bits (793), Expect = 2e-82,   Method: Composition-based stats.
 Identities = 186/269 (69%), Positives = 226/269 (84%)

Query: 11  AWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLWDKVMEGVKLENRTHA 70
           AW+GF+ G+WQ EVN RDFIQ NYTPYEGDESFLA  TE TT+LW+ V+EG+K E+RTHA
Sbjct: 11  AWKGFSAGNWQQEVNTRDFIQTNYTPYEGDESFLADVTETTTSLWNTVLEGIKEESRTHA 70

Query: 71  PVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIKMIEGSCKAYNREL 130
           PVDFDT + STITSHDAGYINK LEKIVGLQT+ PLKR++I  GGI+M++ SC+ Y R+L
Sbjct: 71  PVDFDTDLPSTITSHDAGYINKDLEKIVGLQTDKPLKRSIIANGGIRMVKSSCEVYGRKL 130

Query: 131 DPMIKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGI 190
           D  ++KIFT+YRKTHN+  FD+YT +IL CRKSG++TGLPDAYGRGRIIGDYRR++LYGI
Sbjct: 131 DESVEKIFTDYRKTHNKACFDLYTKEILACRKSGIITGLPDAYGRGRIIGDYRRLSLYGI 190

Query: 191 DYLMKDKLAQFTSLQADLENGVNLEQTIRLREEIAEQHRALGQMKEMAAKYGYDISGPAT 250
           D+L  DK  Q+ S QA LE G +LE+T+RLREE+A+Q +AL  +++M  KYG D+S PA 
Sbjct: 191 DFLKSDKQEQYKSTQAFLEQGHDLEKTLRLREELADQVQALEDIRQMGLKYGIDMSAPAR 250

Query: 251 NAQEAIQWTYFGYLAAVKSQNGAAMSFGR 279
            AQEAIQ+TYFGYLAAVKSQNGAAMS GR
Sbjct: 251 TAQEAIQFTYFGYLAAVKSQNGAAMSLGR 279


>UniRef50_UPI0001C3572E putative pyruvate-formate lyase n=1 Tax=Clostridium hathewayi DSM
           13479 RepID=UPI0001C3572E
          Length = 395

 Score =  249 bits (636), Expect = 3e-64,   Method: Composition-based stats.
 Identities = 67/418 (16%), Positives = 132/418 (31%), Gaps = 65/418 (15%)

Query: 243 YDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEA 302
                  ++ +EA+Q   F + +         +  GR    L  Y        K+   E+
Sbjct: 13  RMKDQKCSSLEEALQRILF-WSSLFWQSQHTLVGIGRLDKVLARY--------KLDIPES 63

Query: 303 QEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLY 362
            +++         +      +      GD       +GG+  +G     + +  F+  + 
Sbjct: 64  VQIIGDFY---SEMHRYFAFKSSGKLLGD-TGQIIVLGGIDPNGDYFCNEYTHIFIEVMR 119

Query: 363 TMGPSPEPNMTILWSEKLPLNFKKFAAKVSI-DTSSLQYENDDLMRPDF--------NND 413
              P P+P + +  S K+P +  + A +            NDD++ P          +  
Sbjct: 120 D-KPIPDPKILLRISSKMPDDLLELAIQCIATGVGCPLLSNDDVIIPALEEFGYTHADAC 178

Query: 414 DYAIACCVSPMIVGKQMQFFGAR-ANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLN 472
           +Y  + C  PM  GK ++    +  N  +      N                       N
Sbjct: 179 NYVTSACWEPMAYGKSLEKNNIKSINFGRCFEKTYNN---------------DEFTACKN 223

Query: 473 YDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMAC------- 525
           ++ ++    + +D  A+  I  LN I     ++          +  +++           
Sbjct: 224 FEGLLTLFLNEVDREAETVINILNNI-----RWEKNPLRSLFTEDCIVKGKDISEGGATY 278

Query: 526 -----GIAGLSVAADSLSAIK---YAKVKPIRDEDGLAI---DFEIEGEYPQ--FGNNDP 572
                   GL+ A DSL  IK   + + K   D+        +FE      +  +G  + 
Sbjct: 279 NNYGVLTVGLANAVDSLLNIKELCFEEKKFTLDQVRSICRESNFESVDSSLKKWYGTENT 338

Query: 573 RVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPF 630
           +V  L   + +R    +               L+ ++ V  G   G T DGR    P 
Sbjct: 339 QVAQLVEQMTDRVYNNLSSYRNRFYGKVKWG-LSASNYVESGAVVGATFDGRNKNEPL 395


>UniRef50_UPI0001C420E7 pyruvate-formate lyase Pfl n=1 Tax=Methanobrevibacter ruminantium
           M1 RepID=UPI0001C420E7
          Length = 677

 Score =  245 bits (626), Expect = 4e-63,   Method: Composition-based stats.
 Identities = 99/653 (15%), Positives = 201/653 (30%), Gaps = 120/653 (18%)

Query: 134 IKKIFTEYRKTHNQGVFDVYTPDILRCRKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYL 193
           IK +  +   T +   F  +  +       G +   P  Y    +I DY    L    + 
Sbjct: 64  IKNLLRKLDITIHPEGFIYFLDEFRNLDYHGQIINSPIDYS---LILDYSIYDLNEFYFN 120

Query: 194 MKD----KLAQFTSLQADLENGVNLEQTI-RLREEIAEQHRALGQMKEMAAKYGYDISGP 248
            K+    +       +  L     +E  I  + + +A+  R      +    +   I   
Sbjct: 121 PKEGPGFRNQSSDYNREMLAILDGIELLIYEINKALAKSSRDDK--SKYIRIFEDIIDKK 178

Query: 249 ATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDH 308
           A++ +EA+Q   F           +  S GR    L+ Y   DL  G IT +EA E++  
Sbjct: 179 ASHFEEALQRILFLNQLL-YQTGHSLNSLGRLDRILEDYYYNDLNDGYITNKEALELIKD 237

Query: 309 LVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLD--GR-TLVTKNSFRFLNTLYTMG 365
            +  L    + +T +   L S        ++GG  +D  G        ++ FL  +  + 
Sbjct: 238 FLKALDSYSWYKTDDESGLAS-----QLITLGGKYIDEFGEYYFYNDLTYIFLEAIGQVN 292

Query: 366 PSPEPNMTILWSEKLPLNFKKFAAKVSIDT------------------------------ 395
           P  +  + +  S K P +    A     +                               
Sbjct: 293 PK-DVKIALRLSYKTPDDLIHLALDCLNENTIYIEEGVAVSFIIDNRIFTADGATIEANI 351

Query: 396 -SSLQYENDDLMRP--------DFNNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYA 446
            S++ + ND+ + P          +  +Y ++  + P  +    +   +  +L K     
Sbjct: 352 DSNIVFSNDEAIIPRLLDFGYSSDDAYNYILSAHLEPTFISCLDEGNLSSISLLKP---- 407

Query: 447 INGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYS 506
           +N   ++K +++           ++N D +ME   + +    ++ I+AL+ I +  D + 
Sbjct: 408 LNDIFEDKNELRF----------IINLDYLMELYKNNLKKEIEEKISALDQIQWNQDPFL 457

Query: 507 -------YEASLMALHDRDVIRTMACGIAGLSVAADSLSAIKYAKVKPIRDEDGLAIDFE 559
                  YE  L                 GL    +SL  +K    +    +        
Sbjct: 458 SLFSAESYENQLDISQGGSRNNHFGIRFYGLQNTVNSLYNLKKIVFEDKTIDLIELDKMR 517

Query: 560 ---------------IEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSV 604
                          ++    +F  N+P + +++ +++      I+      D      +
Sbjct: 518 KNNFKRGKYQETFLLLKNNPVRFPQNNPEIANISNEIIAFIGDSIKDYKNSLDGKLKFGL 577

Query: 605 LTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGI 664
                 +   K+   + D      P                   L S  K          
Sbjct: 578 SAPRYMIKNDKR--ASFDATLKDIP---------------PARLLISSQKTNSDIFIFNS 620

Query: 665 SYTFS---IVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNRE 714
           S  +    I  N +  +       L  ++      EA   G   L +N++  E
Sbjct: 621 SLDYKSSAINGNLIELNINTNDKQLTNIL-----VEAIGYGFDQLQINLIREE 668


>UniRef50_UPI00019247E5 PREDICTED: hypothetical protein, partial n=1 Tax=Hydra magnipapillata
            RepID=UPI00019247E5
          Length = 1179

 Score =  240 bits (613), Expect = 1e-61,   Method: Composition-based stats.
 Identities = 78/514 (15%), Positives = 156/514 (30%), Gaps = 102/514 (19%)

Query: 149  VFDVYTPDILRCRKSGVLTG----LPDAYGRGRIIGDYRRVALYGIDYLMKD-------- 196
                 T DI     S  +      L +  G G +I +Y+++   G+   +K+        
Sbjct: 521  AMPYLTKDIDGELSSEHILAYAHKLSETSGFGHVIPNYQKIIQKGLPTFLKEIKSYMDLS 580

Query: 197  -----KLAQFTSLQADLENGVNLEQTIRLREEIAEQ-----------HRALGQMKEMAAK 240
                 K   +  L A       LE    L   +A +                ++  MA +
Sbjct: 581  TDSMKKEFYWCCLTAFKGIQKYLENYANLALFLANRGVEKDIHFAISSTECNELYSMAQR 640

Query: 241  YGYDI------SGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKA 294
              +        SG   N  EA Q  +  +           +S GR    L+ + +     
Sbjct: 641  LNWLANGNGNGSGKPRNFLEATQLLFTLHCCLHL--CCEPVSIGRFDVILEEFFDP---- 694

Query: 295  GKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSG-------------------DPIWA 335
                ++  Q++VD   +K+     L      +L++                    +    
Sbjct: 695  ---NDRSNQDVVDAFWIKIGEKVQLNRETRLDLYTVGTIAVPYRSDGMFARGDGCNQWVQ 751

Query: 336  TESIGGMGLD--GRTLVT-----KNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFA 388
              +IGG   D  G  ++      + S   L +   + P   P +++     +     K A
Sbjct: 752  QLTIGGFVADDSGERVLPSAKRIEISKLCLRSARRL-PLNAPCLSLRVYSGMDDILLKEA 810

Query: 389  A-KVSIDTSSLQYENDDLMRPDF--------NNDDYAIACCVSPMIVGKQMQFFGARANL 439
            A  +    +     +DDL+ P          +  +Y+   C  P++ GK    F A   L
Sbjct: 811  AYTILSGGAHPVLPHDDLLIPALINTGLNPKDAINYSSDGCYEPIVPGKTEFSF-AYVAL 869

Query: 440  AKTMLYAINGGVD-------EKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYI 492
               +   +N G               V     P  GD+ + D++ +     +       +
Sbjct: 870  LPILEMTLNRGATISNAGPAGMRGYAVSRDLRPDSGDIKSLDDIKKHFGMHLRLQMNDAL 929

Query: 493  TALNIIHYMHDKYSYEASLMALHDRDVIRT------------MACGIAGLSVAADSLSAI 540
            + L   +   +       L ++ D  + +             +   +   +   DSL AI
Sbjct: 930  SGLLSNYGNINTILTTPLLSSMIDGCLEKGRDHYNGGAELKMIGLMVVSFANTVDSLYAI 989

Query: 541  KYAKVKPIRDEDGLAIDFEIEGEYPQFGNNDPRV 574
            +        D+  + +D  +      +G +    
Sbjct: 990  QELCF---GDKSFITLDQLVRTLQSDWGFDLQEP 1020



 Score = 59.6 bits (143), Expect = 4e-07,   Method: Composition-based stats.
 Identities = 39/233 (16%), Positives = 67/233 (28%), Gaps = 32/233 (13%)

Query: 417  IACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEV 476
            I  C+     G+     GA   +   M+ +    VD    +Q   +        +  D++
Sbjct: 952  IDGCLE---KGRDHYNGGAELKMIGLMVVSFANTVDSLYAIQ---ELCFGDKSFITLDQL 1005

Query: 477  MER------MDHFMDWLAKQYITALNIIHYMHDKYSYEASLM----ALHDRDVIRTMACG 526
            +         D    W           I   + K   E +L      L  ++  R     
Sbjct: 1006 VRTLQSDWGFDLQEPWFDPVDGEIGKQISAANMKLIREVALSLPKLGLATKENERNK--- 1062

Query: 527  IAGLSVAADSLSAIK-YAKVKPIRDEDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERF 585
                     S   I        +  E  LA  F      P++      ++++   L E++
Sbjct: 1063 -----NTLSSYCPITLKEIASWLAKEIVLA--FTEVTTLPKY-----TLNNIVKSLTEKY 1110

Query: 586  MKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMH 638
                +K              T    V +G   G + DGRR G P     +P  
Sbjct: 1111 GTSDEKNGKKPFINFQLGSGTFEGYVGWGLGIGASADGRRKGQPLASDMSPAP 1163


>UniRef50_C5EWH7 Putative uncharacterized protein n=2 Tax=Clostridiales bacterium
           1_7_47FAA RepID=C5EWH7_9FIRM
          Length = 499

 Score =  174 bits (440), Expect = 2e-41,   Method: Composition-based stats.
 Identities = 78/510 (15%), Positives = 167/510 (32%), Gaps = 119/510 (23%)

Query: 242 GYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQE 301
            + +  P  +  +A+          + +  G A+  G     L+ +++         E E
Sbjct: 82  EFLMLEPPKDIWDAVGNL-LCLYHNIPADGGLAVYIGCLDRLLEPFVK--------DEDE 132

Query: 302 AQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTL 361
           A++ +  L+  +                    +    +G          T+     L   
Sbjct: 133 ARKAIRFLLTHVDRTI-------------SNAFCHADLG-------PEDTRAGRIILELT 172

Query: 362 YTMGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNNDDYAIACCV 421
             M   P PNMT+++ E  P ++ K A + ++ +S   + ND L R D    DYA+  C 
Sbjct: 173 KEMQR-PCPNMTLMYREDTPDDYMKAALETAMVSSKPSFANDALYRRDM--GDYAVVSCY 229

Query: 422 SPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMD 481
           + + +G        R N+            D+  ++   P+    +        V + +D
Sbjct: 230 NTLPIG-GCGLTLVRLNM------------DQLPRLATDPEDLLNRVIPEAVTAVCDAID 276

Query: 482 HFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVAADSLSAIK 541
              +++           HY  + + Y   L+   DRD +  M  G  GL+   + +  + 
Sbjct: 277 SRCEFIVD-------YCHYYENTFLYREGLIK-KDRDHMVGM-FGFVGLAECVNGILGL- 326

Query: 542 YAKVKPIRDEDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPT 601
             + +                   +FG+   + D L   ++ER  ++I +          
Sbjct: 327 TDEKE-------------------RFGHG-EKADALGEAIMERIRQEIDRRPAKYGKYGL 366

Query: 602 QSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAK 661
            + + +       + T +TP GR    P         G + +     +  +       A 
Sbjct: 367 HAQVGVM------EDTVSTPGGR---IPI--------GEEPELPDQIMNFIRMHKGCDAG 409

Query: 662 DGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAME 721
            G  +             +     L  ++ G F       G ++L+    + +       
Sbjct: 410 CGELF-------PFDDTVKNNPQYLLDILKGAFR-----SGARYLSFYSGDSD------- 450

Query: 722 NPEKYPQLTIRVSGYAVRFNSLTKEQQQDV 751
                    +RV+GY V+ + + K  + ++
Sbjct: 451 --------LVRVTGYLVKKSDIEKFDRDEM 472


>UniRef50_O94132 Formate C-acetyltransferase (Fragment) n=2 Tax=Piromyces sp. E2
           RepID=O94132_9FUNG
          Length = 154

 Score =  170 bits (432), Expect = 1e-40,   Method: Composition-based stats.
 Identities = 73/152 (48%), Positives = 109/152 (71%), Gaps = 2/152 (1%)

Query: 24  VNVRDFIQKNYTPYEGDESFL-AGATEATTTLWDKVMEGVKLENRTHAPVDFDTAVASTI 82
           ++V  +I++N+TPYEGD SFL   A+  T  +W+K  E    E +T+  +D D    ST+
Sbjct: 4   IDVAKWIKENHTPYEGDASFLVTDASAKTKDVWNKCCELRAEEIKTNGCLDVDNKTISTV 63

Query: 83  TSHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIKMIEGSCKAYNRELDPMIKKIFTEYR 142
            SH+AGYI K+ E IVGLQT+APLKR++ PFGG+++++ + KAY+R +DP ++++F   R
Sbjct: 64  NSHEAGYIIKEKEDIVGLQTDAPLKRSIKPFGGVRIVKNALKAYDRTIDPSVEEVFKY-R 122

Query: 143 KTHNQGVFDVYTPDILRCRKSGVLTGLPDAYG 174
           KTHN  VFD+YTP++ + R + +LTGLPD YG
Sbjct: 123 KTHNDCVFDIYTPEMRKARSNAILTGLPDGYG 154


>UniRef50_D1NCN8 Formate C-acetyltransferase n=1 Tax=Haemophilus influenzae HK1212
           RepID=D1NCN8_HAEIN
          Length = 218

 Score =  160 bits (406), Expect = 1e-37,   Method: Composition-based stats.
 Identities = 119/131 (90%), Positives = 127/131 (96%)

Query: 599 IPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFA 658
           +PTQSVLTITSNVVYGKKTGNTPDGRR+GAPFGPGANPMHGRDQKGAVASLTSVAKLPFA
Sbjct: 1   MPTQSVLTITSNVVYGKKTGNTPDGRRSGAPFGPGANPMHGRDQKGAVASLTSVAKLPFA 60

Query: 659 YAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLD 718
           YAKDGISYTFSIVPNALG D E ++ NLAGLMDGYFHHEA++EGGQHLNVNV+NREMLLD
Sbjct: 61  YAKDGISYTFSIVPNALGNDAEAQRRNLAGLMDGYFHHEATVEGGQHLNVNVLNREMLLD 120

Query: 719 AMENPEKYPQL 729
           AMENP+KYPQL
Sbjct: 121 AMENPDKYPQL 131


>UniRef50_B7BHI6 Putative uncharacterized protein (Fragment) n=1 Tax=Parabacteroides
           johnsonii DSM 18315 RepID=B7BHI6_9PORP
          Length = 178

 Score =  143 bits (362), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 49/104 (47%), Positives = 68/104 (65%), Gaps = 1/104 (0%)

Query: 12  WEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLWDKVMEGVKLENRTHAP 71
           W  F    W+ E+NVRDFIQ NY PY+GD++FL  ++E T  +W+K+ E  K+E R    
Sbjct: 76  WAQFKGETWKKEINVRDFIQNNYKPYDGDDTFLVPSSEKTKKVWNKLTEMFKVE-REKGV 134

Query: 72  VDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGG 115
            D +T +   I ++  GYI+K+ E IVGLQT+APLKR + P GG
Sbjct: 135 YDAETKLPQGIDTYGPGYIDKENEVIVGLQTDAPLKRGIFPKGG 178


>UniRef50_Q7NEY2 Glr3745 protein n=1 Tax=Gloeobacter violaceus RepID=Q7NEY2_GLOVI
          Length = 460

 Score =  142 bits (357), Expect = 7e-32,   Method: Composition-based stats.
 Identities = 84/235 (35%), Positives = 120/235 (51%), Gaps = 18/235 (7%)

Query: 168 GLPDAYGRGRIIGDYRRVALYGI-DYLMKDKLAQFTSLQADLENGVNLEQTIRLREEIAE 226
           G   A   G    D R   +YG+ D L  ++L     + +D                +  
Sbjct: 145 GGTPAGAFGADYLDRREELIYGLIDPLDVEQL----PVGSDCRQLALY--GSERLRRLGM 198

Query: 227 QHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDV 286
           Q  A+  ++ +A  YG DI  PA  AQ+AIQWTY   LA      G   S     TF DV
Sbjct: 199 QLGAVETVEALAGCYGLDIGRPAATAQQAIQWTYLALLATRDPLFGRRRSVTGLDTFFDV 258

Query: 287 YIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDG 346
           Y +RDL  G + E+EAQE+VD L++KLR+ +   +  Y  L +           G+  +G
Sbjct: 259 YFQRDLARGLLVEEEAQELVDDLMIKLRLPQPTLSELYLPLAA-----------GVDPEG 307

Query: 347 RTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSSLQYE 401
           R LVT+  FRF+NT Y +GP+ EP++ +LWS  L   F++F  +V+IDTSSL+Y 
Sbjct: 308 RPLVTRTDFRFVNTCYNLGPAAEPHLLVLWSAALSGAFRRFCGEVTIDTSSLRYA 362



 Score =  108 bits (271), Expect = 7e-22,   Method: Composition-based stats.
 Identities = 34/107 (31%), Positives = 48/107 (44%), Gaps = 4/107 (3%)

Query: 9   ATAWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLWDKVMEGVKLENRT 68
           A  W+GF  G+WQ   +V +FI  N  PY GD+S L G TE T  LW +     +    T
Sbjct: 78  ADPWQGFRPGNWQVRTDVENFIAANCDPYLGDDSDLTGPTERTQALWVQAQMLQQAARAT 137

Query: 69  HAPVDFDTAVASTITSHDAGYINKQLEKIVGLQTEAPLKRALIPFGG 115
                      +   +  A Y++++ E I GL    PL    +P G 
Sbjct: 138 ARRSAGPGGTPAG--AFGADYLDRREELIYGLI--DPLDVEQLPVGS 180



 Score = 67.7 bits (164), Expect = 1e-09,   Method: Composition-based stats.
 Identities = 32/107 (29%), Positives = 52/107 (48%), Gaps = 11/107 (10%)

Query: 646 VASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQH 705
            +SL     LP    + G+++T    P+ALG     +  NL   +DG          G H
Sbjct: 356 TSSLRYARALPLP--QTGLAHT--FSPDALGATRTEQVENLGLWLDGQPE-------GDH 404

Query: 706 LNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVI 752
           L +NV  RE LL  +  P K+  LT++++  AV  +SL+   ++ V+
Sbjct: 405 LGINVFGREALLSTLTRPNKFAHLTVQLAEGAVDLHSLSPLGRRQVL 451


>UniRef50_B0PG79 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=B0PG79_9FIRM
          Length = 514

 Score =  128 bits (323), Expect = 6e-28,   Method: Composition-based stats.
 Identities = 64/435 (14%), Positives = 128/435 (29%), Gaps = 98/435 (22%)

Query: 237 MAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGK 296
           M     +          EA+      Y     S     +  GR    L+ +++       
Sbjct: 76  MERGCDFLRLPAPRTLAEALASLTIFYTHV-PSITHFPVYIGRLDRLLEPFVQA------ 128

Query: 297 ITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIG-GMGLDGRTLVTKNSF 355
           +   +A+E +   ++ L  +                 +   +IG    + G         
Sbjct: 129 VGRAQAREPLRLFLIGLDRII-------------GDSFCHANIGPEQTVTGE-------- 167

Query: 356 RFLNTLYTMGPSPEPNMTILWSEK-LPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNNDD 414
             +  L  +  +  PN+T+L+     P +F       ++  ++  +  D   R     + 
Sbjct: 168 LIVELLPELQNAV-PNLTLLYDPAVTPDDFAIRCISCALRCANPAFAFDPYYR-ARIGEQ 225

Query: 415 YAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYD 474
           Y IA C + + VG    F  +R  L K                  GP          + D
Sbjct: 226 YGIASCYNGLYVGGGA-FSLSRIRLGKIAE------------RCTGPDDFFFNRLPESVD 272

Query: 475 EVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVAA 534
                M+  + ++A+              K ++      LH    +     G+ G++   
Sbjct: 273 AACRFMEAKIRFIAE---------EIPFFKSNFLVREGFLHRDKFV--GLFGLVGMNECV 321

Query: 535 DSLSAIKYAKVKPIRDEDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHT 594
           ++L                     ++ G+  ++G +  R + L + ++E   K++Q   +
Sbjct: 322 NTLM--------------------DLSGDTGRYGPD-ERANQLGLRIMESIEKQVQAFES 360

Query: 595 YRDAIPTQSVLTITSNVVYGKKTGNTPDGRRA-----------------GAPFGPGAN-- 635
              A+     L + + V      G TP  R A                    F  G    
Sbjct: 361 RYCAVNGHRFL-LHAQVGAVGDNGVTPGVRIAIGSELPLYDHLRQAGLFHHFFPSGVGDI 419

Query: 636 -PMHGRDQKGAVASL 649
            P      +   A L
Sbjct: 420 FPFDQTAVQNPAAVL 434


>UniRef50_C8W8Y4 Putative uncharacterized protein n=3 Tax=Bacteria
           RepID=C8W8Y4_ATOPD
          Length = 500

 Score =  123 bits (310), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 77/539 (14%), Positives = 159/539 (29%), Gaps = 161/539 (29%)

Query: 154 TPDILRCRKSGVLTGLPD---AYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLEN 210
           T +  R  K+  +  + +    Y    I  DY+  A  G ++L  DK      L      
Sbjct: 36  TAEFDRLFKAHAIDDMCEGNAPYRPRYICPDYQVFAQNGSEFLRFDKPENLDDL------ 89

Query: 211 GVNLEQTIRLREEIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQ 270
                                  +  +A  Y    S                        
Sbjct: 90  -----------------------LWGLATLYDNVPS-----------------------V 103

Query: 271 NGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSG 330
               +  G+    +D ++E       +T+ E         +K R+ RFL   +   + SG
Sbjct: 104 TSRPVYVGQLDKIIDPFLE------GMTDDE---------IKPRLRRFLNHIDRT-VASG 147

Query: 331 DPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEK-LPLNFKKFAA 389
                  +IG          T+     L     +  +  PN T+ +  +     F + A 
Sbjct: 148 Y---CHANIG-------PEDTRAGRLLLEVERELMNAV-PNFTLKYDPEITSDEFMRLAV 196

Query: 390 KVSIDTSSLQYENDDLMRPDFNNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAING 449
           K ++  S+  + N  + +  +  + Y +  C + + +G       +R  L      A N 
Sbjct: 197 KTTMVCSNPAFANHRIHKETYPGE-YTVVSCYNVLPMGGGAYTL-SRVLLPGLAKLATN- 253

Query: 450 GVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEA 509
            VD+ +   +   +           EV+  M+  + ++ +               +   +
Sbjct: 254 -VDDFMNNLLPTATS----------EVLNFMNERVRFIVEDS------------NFFETS 290

Query: 510 SLMALHDRDVIRTMACGIAGLSVAADSLSAIKYAKVKPIRDEDGLAIDFEIEGEYPQFGN 569
            L    +  + R   CG+ G++  ++ ++ + +                        +G 
Sbjct: 291 FLA--KEGLISRDRFCGMFGVAGMSECVAELLHLDSSRT------------------YGK 330

Query: 570 NDPRVDDLAVDLVERFMKKIQKLHTYRDAIPT---QSVLTITSNVVYGKKTGNTPDGR-- 624
           +D      A +L ++ M KI       DA+ +       T+ +   +  + G TP  R  
Sbjct: 331 DDE-----ANELADQIMVKIADQVNSFDAVYSEVFGGRFTLHAQAGFSDQKGVTPGVRIK 385

Query: 625 ----------------RAGAPFGPGAN---PMHGRDQKGAVASL---TSVAKLPFAYAK 661
                           R    F  G +   P     ++   A +    +   +   Y  
Sbjct: 386 VGDEPANLYDHIRHSARMHRFFNSGVSDIFPAEPTAERNPDAVIDVVKAAFSIDDKYLS 444


>UniRef50_B1EF41 Keto-acid formate acetyltransferase (Keto-acid formate-lyase) n=3
          Tax=Enterobacteriaceae RepID=B1EF41_9ESCH
          Length = 96

 Score =  122 bits (307), Expect = 4e-26,   Method: Composition-based stats.
 Identities = 55/82 (67%), Positives = 69/82 (84%)

Query: 5  NEKLATAWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLWDKVMEGVKL 64
          ++  A AW GF   DW++E+NVRDFIQ NYTPYEGDESFLA AT ATT LW+KVMEG+++
Sbjct: 9  DKLYANAWLGFKGTDWKDEINVRDFIQHNYTPYEGDESFLAEATPATTALWEKVMEGIRI 68

Query: 65 ENRTHAPVDFDTAVASTITSHD 86
          EN THAP+DFDT +A+TIT+H+
Sbjct: 69 ENATHAPLDFDTNIATTITAHE 90


>UniRef50_A6BGV7 Putative uncharacterized protein n=1 Tax=Dorea longicatena DSM
           13814 RepID=A6BGV7_9FIRM
          Length = 121

 Score =  118 bits (295), Expect = 9e-25,   Method: Composition-based stats.
 Identities = 27/122 (22%), Positives = 44/122 (36%), Gaps = 1/122 (0%)

Query: 581 LVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGR 640
           +      +I+   +      T  +L ++ N   G + G  P GR A  P   G +P  G 
Sbjct: 1   MFAFIANEIESYRSKFG-TMTPGILPVSGNTPVGLEVGALPSGRHAWKPLADGVSPNGGT 59

Query: 641 DQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASI 700
           D +G  A L SV+ LP      G      I P  L  ++ +       +   ++      
Sbjct: 60  DTEGPGAVLKSVSHLPHDRFVQGTFLNMKIEPEILNSENGIMPHPCGRVYGIFYGTWKGC 119

Query: 701 EG 702
            G
Sbjct: 120 TG 121


>UniRef50_C0A3H9 Pyruvate-formate lyase-like protein (Fragment) n=1 Tax=Opitutaceae
           bacterium TAV2 RepID=C0A3H9_9BACT
          Length = 322

 Score =  116 bits (290), Expect = 4e-24,   Method: Composition-based stats.
 Identities = 37/217 (17%), Positives = 73/217 (33%), Gaps = 32/217 (14%)

Query: 122 SCKAYNRELDPMIKKIFTEYR-KTHNQGVFDVYTPDILRCRKSGVLTGLP----DAYGRG 176
               + R     ++ +   +R +T +  +   +  D+ R          P      Y   
Sbjct: 108 IDTTHRRH----VEDMLDYWRTRTTHAKIRAAHPEDVRRLLPEDNWPNHPGSAFPLYRIA 163

Query: 177 RIIGDYRRVALYGIDYLMKDKLAQFTSLQADLENGVN-----------LEQTIRLREEIA 225
            I  DY+++   G+  L+++   Q  +    L    +           LE  + +    A
Sbjct: 164 GITLDYKKLLRNGLPGLIQNIQRQLAAPPGPLPLPHDAHDLLENTCTVLETLLAIIRRHA 223

Query: 226 EQHRALGQM------KEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGR 279
            + R L +         +A         P    +EAIQ  +   LA         +++GR
Sbjct: 224 TEARTLARAHPASGAAAIADTLDALTQRPPATLREAIQLAWLASLA------AGVVNYGR 277

Query: 280 TSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMV 316
              +L  +++ DL AG +T   A E +      +   
Sbjct: 278 MDIWLAPFLDHDLDAGLLTPDAALEQLKDFWRHIATT 314


>UniRef50_B9Y9Q5 Putative uncharacterized protein n=1 Tax=Holdemania filiformis DSM
           12042 RepID=B9Y9Q5_9FIRM
          Length = 503

 Score =  115 bits (289), Expect = 5e-24,   Method: Composition-based stats.
 Identities = 76/502 (15%), Positives = 143/502 (28%), Gaps = 113/502 (22%)

Query: 248 PATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVD 307
           P  +  EA       Y     S     +  G     L+ ++ ++      T Q A++++ 
Sbjct: 83  PPQDLLEATNALLIMYHHV-PSITSFPVYLGNLDELLEPFVLKE------TPQRAKQILK 135

Query: 308 HLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPS 367
             ++ +                    +    +G          ++     L     M   
Sbjct: 136 MFLLHIDRTLT-------------DSFVHADLG-------PQASRTGELILELTEEM-QC 174

Query: 368 PEPNMTILWSEK-LPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNNDDYAIACCVSPMIV 426
             PN+T+ +  +    +F K  A   + T+   + N  +   ++  ++YAIA C + + V
Sbjct: 175 AMPNLTLKYDSQQTSDDFLKRCALCMLKTAKPSFANHAMFTREW-GENYAIASCYNGLKV 233

Query: 427 GKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDW 486
           G    F   R  L      ++             P+             ++E M+  + +
Sbjct: 234 GGG-GFTLPRIRL---YECSL---------KAKDPQDFLDNVLPRYVQIMLEMMEDRIRF 280

Query: 487 LAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVAADSLSAIKYAKVK 546
           + +                  E             T   G+ GL+   + L  I      
Sbjct: 281 IVETSAFFKANFLVTEGFVKLENF-----------TGMFGMVGLAECVNHLLGI------ 323

Query: 547 PIRDEDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLT 606
                         E     +GNN    DDL V +++R    +    +            
Sbjct: 324 --------------EDPRRGYGNNVQ-ADDLGVKILQRLSDLVAGFTSAY-------CDG 361

Query: 607 ITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISY 666
              +     + G   DGR       PGA    G +  G +  +   A++   +   GI  
Sbjct: 362 TDHHFRLHAQVGIDSDGREN----SPGARIPVGAEP-GMLKQIQHAARM-HGFFPTGIGD 415

Query: 667 TFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKY 726
            F      L   +      L  ++ G          G   N                   
Sbjct: 416 IFKFEETWLNTPE-----ALGDIIKGAMASGMRYFSGYLEN------------------- 451

Query: 727 PQLTIRVSGYAVRFNSLTKEQQ 748
               +RV+GY V+ + L K  Q
Sbjct: 452 -NDVVRVTGYLVKKSELAKLDQ 472


>UniRef50_A1SHU8 Putative uncharacterized protein n=1 Tax=Nocardioides sp. JS614
           RepID=A1SHU8_NOCSJ
          Length = 515

 Score =  108 bits (269), Expect = 1e-21,   Method: Composition-based stats.
 Identities = 77/504 (15%), Positives = 142/504 (28%), Gaps = 123/504 (24%)

Query: 248 PATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVD 307
           PAT+  EA+  T     + V S  G  +  G     L+ Y+E       ++E+E    + 
Sbjct: 88  PATDLDEAL-ATLLIGYSQVPSITGYPVWLGDLDALLEPYVE------GVSEEELHRKLR 140

Query: 308 HLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPS 367
              + L  +                 +   ++G          ++     L     +   
Sbjct: 141 LFWISLDRMFP-------------DAFTHANLG-------PDDSRVGRMALRLERELLQV 180

Query: 368 PEPNMTILWSE-KLPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNNDDYAIACCVSPMIV 426
             PN+++     + P ++ + A +         + N  +M  D     Y +  C + ++ 
Sbjct: 181 V-PNLSLKVDPERTPDDYVRDAVETVFACGKPHFVNHPMMVGDLGAA-YGVVSCYNSLVA 238

Query: 427 GKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDW 486
           G        R NL      A+          +     E +   V    E+ME     +  
Sbjct: 239 GGGSHTL-TRLNLR---EVAL-----RHEGERTSFLDELLPRYVELTAELMEA---RIRH 286

Query: 487 LAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVAADSLSAIKYAKVK 546
           L ++     +           +                 G+ GL+ A             
Sbjct: 287 LVEEARFFEHSWLVTDGLLHLDRYAAMF-----------GVYGLAEAV------------ 323

Query: 547 PIRDEDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYR-----DAIPT 601
                   +I  E EG   ++G++D   D+LA+ ++ R  + +                 
Sbjct: 324 --------SIVLEHEGVEARYGHDD-VADELALQILTRVHELVAARPMPYCEGNGGRAFL 374

Query: 602 QSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAK 661
            S   I S        G T   R        G  P   R  +              A   
Sbjct: 375 HSQSGIDS------DLGVTAGCR-----IPVGDEPDLLRHLRTITP--------NHALFP 415

Query: 662 DGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAME 721
            GIS        A           +  ++ G F           +  N+ + +       
Sbjct: 416 AGIS-----DVLAFDDTARRNPDAVVDVIRGAFRTGMRD-----VTFNLDSND------- 458

Query: 722 NPEKYPQLTIRVSGYAVRFNSLTK 745
                    IR++GY VR + L K
Sbjct: 459 --------FIRITGYLVRKSDLAK 474


>UniRef50_Q3ADQ8 Putative uncharacterized protein n=1 Tax=Carboxydothermus
           hydrogenoformans Z-2901 RepID=Q3ADQ8_CARHZ
          Length = 511

 Score =  104 bits (260), Expect = 1e-20,   Method: Composition-based stats.
 Identities = 35/203 (17%), Positives = 76/203 (37%), Gaps = 30/203 (14%)

Query: 237 MAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGK 296
           M     Y    P  +  EA+      Y     S     +  G+    L+ ++   L AG 
Sbjct: 83  MEKGSEYLNLKPPQDLFEAVNALLIIYRYV-PSITSYPVYLGQVDEHLEPFV---LAAG- 137

Query: 297 ITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFR 356
             E+ +++++   ++++  V                 +   +IG          T+    
Sbjct: 138 --EELSEKLLKMFLVQIDRVLP-------------DGFVHMNIG-------PKDTRTGRL 175

Query: 357 FLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNNDDYA 416
            L     +  +  PN+++ ++E+ P +F   A K +++     + ND  ++ D +   Y 
Sbjct: 176 ILKLERELKQAV-PNISLKYNEETPDSFAIEAVKTALEIGKPYFVNDRELKEDLDPA-YG 233

Query: 417 IACCVSPMIVGKQMQFFGARANL 439
           +A C + +++G        R NL
Sbjct: 234 VASCYNTLLIGGGSFTL-VRLNL 255


>UniRef50_A3DFS4 Putative uncharacterized protein n=22 Tax=Clostridium
           RepID=A3DFS4_CLOTH
          Length = 514

 Score =  103 bits (256), Expect = 3e-20,   Method: Composition-based stats.
 Identities = 49/373 (13%), Positives = 113/373 (30%), Gaps = 83/373 (22%)

Query: 237 MAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGK 296
           M     +    P T+  EA+      Y       N   +  G+  T L+ +++       
Sbjct: 87  MKEGSRFLQLAPPTDLYEALNSLLIFYKHVPSVTN-FPVYLGQLDTLLEPFMQD------ 139

Query: 297 ITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFR 356
           + +  A++++   ++ +                    ++  +IG          T+    
Sbjct: 140 VDDTTAKKLLRGFLVHVDRTIL-------------DSFSHANIG-------PKPTRTGRL 179

Query: 357 FLNTLYTMGPSPEPNMTILWSEK-LPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNNDDY 415
            L     +  +  PN+T+ + E     +F   A K ++ ++   + N  +   +   ++Y
Sbjct: 180 LLEVEAELTQAV-PNLTLKYEEGVTDDDFAIQAVKTALRSAKPSFANHRMFTQEL-GENY 237

Query: 416 AIACCVSPMIVGKQMQFFGARA--NLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNY 473
            IA C + + +G            N+AK                  G +           
Sbjct: 238 VIASCYNGLPLGGGSYTLCRLILGNIAK---------------RAGGIEDFRTNQLPYVM 282

Query: 474 DEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVA 533
           D +   MD  + +  ++     N      +  + E  +       +      G+ GL+  
Sbjct: 283 DIMARYMDSRIRFEVEESGFFEN------NFLAREGFISRKRFTAM-----FGLVGLAEC 331

Query: 534 ADSLSAIKYAKVKPIRDEDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLH 593
            + L                     E EG   +FG++     +L   ++++  +  +K H
Sbjct: 332 VNILL--------------------EKEGRPGRFGHD-EYATELGESIIKQIYEFSEKHH 370

Query: 594 TYR----DAIPTQ 602
                        
Sbjct: 371 NPYCEITGGHFLL 383


>UniRef50_B7UH18 Autonomous glycyl radical cofactor n=257 Tax=root RepID=GRCA_ECO27
          Length = 127

 Score =  103 bits (256), Expect = 4e-20,   Method: Composition-based stats.
 Identities = 49/67 (73%), Positives = 57/67 (85%)

Query: 694 FHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVIT 753
              E  +EGGQHLNVNV+ RE L DA+++PEKYPQLTIRVSGYAVRFNSLT EQQ+DVI 
Sbjct: 61  VKPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSGYAVRFNSLTPEQQRDVIA 120

Query: 754 RTFTQSM 760
           RTFT+S+
Sbjct: 121 RTFTESL 127


>UniRef50_Q70BJ5 Putative uncharacterized protein n=4 Tax=Siphoviridae
           RepID=Q70BJ5_BPBF2
          Length = 122

 Score =  100 bits (249), Expect = 2e-19,   Method: Composition-based stats.
 Identities = 49/67 (73%), Positives = 58/67 (86%)

Query: 694 FHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVIT 753
                 IEGGQHLNVNV++R+ LLDA ++PEKYPQLTIRVSGYAVRFN+LT+EQQ DVI+
Sbjct: 56  VEVAPQIEGGQHLNVNVLSRDQLLDAQKHPEKYPQLTIRVSGYAVRFNALTREQQNDVIS 115

Query: 754 RTFTQSM 760
           RTFTQ+M
Sbjct: 116 RTFTQAM 122


>UniRef50_Q5E2Y6 Autonomous glycyl radical cofactor n=6 Tax=Proteobacteria
           RepID=GRCA_VIBF1
          Length = 125

 Score = 99.3 bits (246), Expect = 5e-19,   Method: Composition-based stats.
 Identities = 48/70 (68%), Positives = 56/70 (80%)

Query: 691 DGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQD 750
           D        IEGGQHLNVNV+ R+ L DA+++PE YPQLTIRVSGYAVRFNSLT EQQ+D
Sbjct: 56  DVAIEKAPKIEGGQHLNVNVLQRDTLEDAVKHPENYPQLTIRVSGYAVRFNSLTTEQQKD 115

Query: 751 VITRTFTQSM 760
           VI RTFT+S+
Sbjct: 116 VIARTFTESL 125


>UniRef50_Q6RHV7 Putative uncharacterized protein vs.6 n=1 Tax=Aeromonas phage 65
           RepID=Q6RHV7_9CAUD
          Length = 120

 Score = 99.3 bits (246), Expect = 6e-19,   Method: Composition-based stats.
 Identities = 47/73 (64%), Positives = 58/73 (79%)

Query: 688 GLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQ 747
            ++         +EGGQHLNVNV+N+E L DA++ PEKYPQLTIRVSGYAVRFNSLT EQ
Sbjct: 48  NMVSVNVEQVPLVEGGQHLNVNVLNKETLEDAIKFPEKYPQLTIRVSGYAVRFNSLTPEQ 107

Query: 748 QQDVITRTFTQSM 760
           Q+DV++RTFT S+
Sbjct: 108 QRDVVSRTFTASL 120


>UniRef50_Q56EP5 Vs.6 n=5 Tax=unclassified T4-like viruses RepID=Q56EP5_9CAUD
          Length = 122

 Score = 98.5 bits (244), Expect = 9e-19,   Method: Composition-based stats.
 Identities = 51/70 (72%), Positives = 60/70 (85%), Gaps = 2/70 (2%)

Query: 693 YFH--HEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQD 750
           +F    E ++EGGQHLNVNV++R  L DA+ NPEKYPQLTIRVSGYAVRFN+LT EQQ+D
Sbjct: 53  FFDVQSEPTVEGGQHLNVNVLDRNTLEDAIVNPEKYPQLTIRVSGYAVRFNALTPEQQRD 112

Query: 751 VITRTFTQSM 760
           VITRTFTQS+
Sbjct: 113 VITRTFTQSL 122


>UniRef50_C0VY69 Putative uncharacterized protein n=1 Tax=Actinomyces coleocanis DSM
           15436 RepID=C0VY69_9ACTO
          Length = 121

 Score = 98.1 bits (243), Expect = 1e-18,   Method: Composition-based stats.
 Identities = 41/71 (57%), Positives = 51/71 (71%)

Query: 690 MDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQ 749
           M         ++G  H N+NV+N++ L+DAMENPEKYPQLT+RVSGYAV F  LT+EQQ 
Sbjct: 51  MKASRAATGGVKGLYHANINVLNKDTLVDAMENPEKYPQLTVRVSGYAVNFVRLTREQQL 110

Query: 750 DVITRTFTQSM 760
           DVI+RTF   M
Sbjct: 111 DVISRTFHDGM 121


>UniRef50_D1AIQ0 Putative uncharacterized protein n=4 Tax=Bacteria
           RepID=D1AIQ0_SEBTE
          Length = 495

 Score = 96.6 bits (239), Expect = 3e-18,   Method: Composition-based stats.
 Identities = 72/507 (14%), Positives = 154/507 (30%), Gaps = 120/507 (23%)

Query: 247 GPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMV 306
            PA +  EA       Y     S     +  G     L+ YI+         E+EA   +
Sbjct: 80  EPAKDIWEATHNLLMLYKHV-PSITTMPVYLGNLDYMLEPYIK--------DEEEAYRAI 130

Query: 307 DHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGP 366
              +  +                    +   +IG          TK +F  L  +  +  
Sbjct: 131 KLFLKHIDTTIT-------------DSFCHSNIG-------PKETKAAFIILRVMEEL-Q 169

Query: 367 SPEPNMTILWSEKLPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNNDDYAIACCVSPMIV 426
            P PN+T+ +SE+        A + ++ T+   + N  +   +F   DY I  C + + V
Sbjct: 170 LPTPNLTLKYSEETSDKLALAAVEAALVTAKPSFANHKVYSENFKG-DYGIVSCYNGLKV 228

Query: 427 GKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDW 486
           G           L +  L  ++   D     Q   +  P         ++ + M  ++D 
Sbjct: 229 GGGAYT------LVRVKLGELSKKADSV--EQFMDEVLP---------DLADAMLGYIDE 271

Query: 487 LAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMA---CGIAGLSVAADSLSAIKYA 543
             +  +            +     L    +  + R       G+ GL+   ++L      
Sbjct: 272 RVRFIVEET--------PFFESNFLA--KEGLIERDKFTGLFGVVGLAECVNNLL----- 316

Query: 544 KVKPIRDEDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQS 603
                          + E +  +FG    + + L + +V++  +K++          T  
Sbjct: 317 ---------------KAENQEERFGY-SDKANQLGMQIVQKLDEKVKGHKNKY-CPFTDG 359

Query: 604 VLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDG 663
              + + V     T ++P  R              G + +       S     +  +  G
Sbjct: 360 NHLLHAQVGIDTDTSDSPGCRI-----------PVGEEPEIWDHLTQSAPFHKYFPSGIG 408

Query: 664 ISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENP 723
             +T            +     +  ++ G F+          ++V   + +         
Sbjct: 409 DIFT-------FDDTYKKNPQAILDIIRGAFNSTDLRF----ISVYSSDSD--------- 448

Query: 724 EKYPQLTIRVSGYAVRFNSLTKEQQQD 750
                  +RV+GY V+ + + K ++ +
Sbjct: 449 ------VVRVTGYLVKKSEIAKLEKGE 469


>UniRef50_O94139 Formate C-acetyltransferase (Fragment) n=2 Tax=Piromyces sp. E2
           RepID=O94139_9FUNG
          Length = 140

 Score = 92.0 bits (227), Expect = 7e-17,   Method: Composition-based stats.
 Identities = 28/62 (45%), Positives = 37/62 (59%)

Query: 21  QNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLWDKVMEGVKLENRTHAPVDFDTAVAS 80
           ++E++V  +I+K+YTPYEGD SFLAG TE T  L+ K  E +  E       D D    S
Sbjct: 79  KSEIDVEGWIKKHYTPYEGDGSFLAGPTEKTKKLFAKAEEYLAKERANGGLYDVDPHTPS 138

Query: 81  TI 82
           TI
Sbjct: 139 TI 140


>UniRef50_P37342 Uncharacterized protein yjjI n=153 Tax=Proteobacteria
           RepID=YJJI_ECOLI
          Length = 516

 Score = 89.3 bits (220), Expect = 6e-16,   Method: Composition-based stats.
 Identities = 71/510 (13%), Positives = 129/510 (25%), Gaps = 115/510 (22%)

Query: 237 MAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGK 296
           +A    +     A +  +A+          V S     +  G+    L  Y+        
Sbjct: 80  LANGSEWLELEGAKDLDDAL-SLLTILYHHVPSVTSMPVYLGQLDALLQPYVR------I 132

Query: 297 ITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFR 356
           +T+ E    +      L                    +   +IG          +  +  
Sbjct: 133 LTQDEIDVRIKRFWRYLDRTLP-------------DAFMHANIG-------PSDSPITRA 172

Query: 357 FLNTLYTMGPSPEPNMTILWSEK-LPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNNDDY 415
            L     +     PN+T ++  +  P +     AK   + S     N  +    F    Y
Sbjct: 173 ILRADAELKQ-VSPNLTFIYDPEITPDDLLLEVAKNICECSKPHIANGPVHDKIFTKGGY 231

Query: 416 AIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDE 475
            I  C +  +          R NL                           +       +
Sbjct: 232 GIVSCYN-SLPLAGGGSTLVRLNLKAIAE------------RSESLDDFFTRTLPHYCQQ 278

Query: 476 VMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVAAD 535
            +  +D   ++L +Q     N         + E  +              G+ GL+ A +
Sbjct: 279 QIAIIDARCEFLYQQSHFFENSFLVKEGLINPERFVPMF-----------GMYGLAEAVN 327

Query: 536 SLSAIKYAKVKPIRDEDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTY 595
            L                     E EG   ++G      +++   +  +  + +      
Sbjct: 328 LL--------------------CEKEGIAARYGKEAA-ANEVGYRISAQLAEFVANTPVK 366

Query: 596 RDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKL 655
                   +   +         G TP  R    P+G   +P+                  
Sbjct: 367 YGWQKRAMLHAQS---GISSDIGTTPGARL---PYGDEPDPITHLQTVAP---------- 410

Query: 656 PFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREM 715
             AY   GIS         L +  +     L  L  G F       G +    NV   + 
Sbjct: 411 HHAYYYSGIS-----DILTLDETIKRNPQALVQLCLGAFKA-----GMREFTANVSGND- 459

Query: 716 LLDAMENPEKYPQLTIRVSGYAVRFNSLTK 745
                          +RV+GY VR + L K
Sbjct: 460 --------------LVRVTGYMVRLSDLEK 475


>UniRef50_Q76Z52 Putative uncharacterized protein vs.6 n=1 Tax=Aeromonas phage Aeh1
           RepID=Q76Z52_9CAUD
          Length = 125

 Score = 88.9 bits (219), Expect = 7e-16,   Method: Composition-based stats.
 Identities = 39/67 (58%), Positives = 53/67 (79%)

Query: 694 FHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVIT 753
              E+    GQHLNVNV++RE L+ A+E+P +YP L +R+SGYAVRFN+LT EQQ+D++T
Sbjct: 59  VEIESVQHAGQHLNVNVLSREHLMLAIEDPNRYPNLVVRISGYAVRFNALTPEQQRDIVT 118

Query: 754 RTFTQSM 760
           RTFT+ M
Sbjct: 119 RTFTKHM 125


>UniRef50_UPI0001C361F0 hypothetical protein ChatD1_32948 n=2 Tax=Clostridium hathewayi DSM
           13479 RepID=UPI0001C361F0
          Length = 516

 Score = 87.7 bits (216), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 75/568 (13%), Positives = 155/568 (27%), Gaps = 124/568 (21%)

Query: 193 LMKDKLAQFTSLQADLENGVNLE--QTIRLREEIA-----EQHRALGQMKEMAAKYGYDI 245
           L ++       L    +     E      L E  A            +     +K+    
Sbjct: 40  LAREAEDSLEVLDIPPKTRAYFETGALNDLFEGHAPYRPRYIMPDYKKFVRQGSKFLRI- 98

Query: 246 SGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEM 305
             P     E +      Y     S  G  +  G   T ++ +         + + E +E 
Sbjct: 99  -EPPKTLDELLTGLEILYHHV-PSITGFPVYLGELDTMIEPF------TTGLADDEVKEK 150

Query: 306 VDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMG 365
           +   ++ L                    +   ++G          T+     L     + 
Sbjct: 151 IRLFLIYLDRTIT-------------DSFCHGNLGAKP-------TRTGRIILELEKELQ 190

Query: 366 PSPEPNMTILWSEK-LPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNNDDYAIACCVSPM 424
            +  PN+T+ +     P  + + A   S+  ++    ND   R  +   +Y I+ C + +
Sbjct: 191 NAV-PNLTLKYDPDVTPDEYAELAVSTSLYCANPAICNDADNRTTYP-CEYGISSCYNIL 248

Query: 425 IVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFM 484
            VG       +R  L              K       +  P         + +  + ++M
Sbjct: 249 PVGGGAYTL-SRITLT---ELV----KSAKSTEHFLKELLP---------DCLNAVGNYM 291

Query: 485 DWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVAADSLSAIKYAK 544
           +   K  +                     L +R+    M  G+ GL+   ++L A     
Sbjct: 292 NERVKFLVERSGFFESSFL------VREGLIEREKFVGM-FGVTGLAECVNALMA----- 339

Query: 545 VKPIRDEDGLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSV 604
                                ++G+     DDL V ++E   K +         I     
Sbjct: 340 -----------------DTGKRYGH-SAESDDLGVQIMEIIQKFVADFPAVYSEIGR-GH 380

Query: 605 LTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGI 664
             + + V      G T     +G     G  P +  D         S     +     G 
Sbjct: 381 YLLHAQVGLDSDKGIT-----SGVRIPVGDEPENLLDH-----LRHSARFHEYFPTGVGD 430

Query: 665 SYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPE 724
            +                   L  ++ G F       G ++++    + +          
Sbjct: 431 IF-------PFAVTARNNPGALVDIVKGSFQL-----GVKYMSFYASDSD---------- 468

Query: 725 KYPQLTIRVSGYAVRFNSLTKEQQQDVI 752
                 +R++G+ V+ + + K +  DV+
Sbjct: 469 -----LVRITGFLVKRSEMEKYRNHDVV 491


>UniRef50_C3RPZ3 Formate C-acetyltransferase n=1 Tax=Mollicutes bacterium D7
           RepID=C3RPZ3_9MOLU
          Length = 166

 Score = 86.2 bits (212), Expect = 4e-15,   Method: Composition-based stats.
 Identities = 25/154 (16%), Positives = 44/154 (28%), Gaps = 15/154 (9%)

Query: 476 VMERMDHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVAAD 535
           + ++     D++        N I Y       +     L+             G   + D
Sbjct: 2   LAKQEKFEYDYMNNHCGYLFNSILY---DNCIDRGKSLLNGGIDYLGGTLETYGNVNSGD 58

Query: 536 SLSAIKYAKVKPIR---DEDGLAIDFEIEG---------EYPQFGNNDPRVDDLAVDLVE 583
           SL AIK            +   AI     G            ++GN++P VD++  +L +
Sbjct: 59  SLYAIKKLVFDDKEIRYKDMVDAIRNNFIGYEEIREKCLNVIKYGNDNPEVDEMINELNQ 118

Query: 584 RFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKT 617
                 +             V+ I      G  T
Sbjct: 119 YVAVTTKSKSEKYGLSSYLIVIIIKYPFTRGCFT 152


>UniRef50_C3RRJ0 Formate acetyltransferase (Fragment) n=2 Tax=Bacteria
           RepID=C3RRJ0_9MOLU
          Length = 246

 Score = 81.2 bits (199), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 30/180 (16%), Positives = 70/180 (38%), Gaps = 19/180 (10%)

Query: 117 KMIEGSCKAYNRELDPMIKKIFTEYR-KTHNQGVFDVYTPDILRCRKSGVLTGLPDA--- 172
           ++ +     ++ E    +++++T +  +   + +   Y  DI                  
Sbjct: 37  RLAKLIEGTHDVE-KEELEELYTFWADENDKERLRRYYPNDIKELMPYDDFENDYYTAYP 95

Query: 173 -YGRGRIIGDYRRVALYGIDYLMKDKLAQ--FTSLQADLENGVNLEQTIRLREEIAEQHR 229
            Y  G    D+ ++   GID L+ +  +Q   + L+A  ++ + L++ I+L  +      
Sbjct: 96  LYRLGGAYLDFEKLFDLGIDGLIHEIDSQPLNSFLRACKKSLIYLKELIKLYRDDVMDIN 155

Query: 230 ALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIE 289
                 E+A      +     N +EAIQ  +  Y+   + +N     +GR    L  +++
Sbjct: 156 P-----ELAYTLNELLEHRPQNMKEAIQLMW-IYVGVSEIRN-----YGRMDNQLARFLD 204


>UniRef50_P44744 Uncharacterized protein HI0521 n=23 Tax=Bacteria RepID=Y521_HAEIN
          Length = 514

 Score = 79.6 bits (195), Expect = 4e-13,   Method: Composition-based stats.
 Identities = 35/198 (17%), Positives = 62/198 (31%), Gaps = 32/198 (16%)

Query: 237 MAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGK 296
           +     +    P  +  EA+      Y     S     +  GR    L+ +         
Sbjct: 78  IQKGCEFLELPPPKDLDEALDGLLILYSHV-PSITTYPVYIGRLDVLLEPF--------- 127

Query: 297 ITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFR 356
           IT++E         +K++                   +   +IG          TK    
Sbjct: 128 ITDEEKD------YIKIKRFLNHIDKTVP------DSFCHANIGPYD-------TKAGRL 168

Query: 357 FLNTLYTMGPSPEPNMTILWSE-KLPLNFKKFAAKVSIDTSSLQYENDDLMRPDFNNDDY 415
            L  +  +  +P PNMTI + + K    F + AAK  +  S   + ND     D   ++Y
Sbjct: 169 ILRAVIDLE-APTPNMTIRYDKSKTSREFAELAAKACLLVSKPSFANDAYYISDL-GEEY 226

Query: 416 AIACCVSPMIVGKQMQFF 433
            +A C + +         
Sbjct: 227 GVASCYNALPECGGAYTL 244


>UniRef50_UPI00017435F3 putative formate acetyltransferase n=1 Tax=candidate division TM7
           single-cell isolate TM7a RepID=UPI00017435F3
          Length = 65

 Score = 65.4 bits (158), Expect = 9e-09,   Method: Composition-based stats.
 Identities = 14/51 (27%), Positives = 18/51 (35%)

Query: 632 PGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVR 682
            G +P  G D  G  A L SV KLP      G        P  +   ++  
Sbjct: 13  EGGSPTQGTDTNGPTAVLNSVNKLPTLMITGGQLLNQKYSPELVNTPEQFE 63


>UniRef50_UPI0001742832 Formate acetyltransferase n=1 Tax=candidate division TM7
          single-cell isolate TM7a RepID=UPI0001742832
          Length = 53

 Score = 63.5 bits (153), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 22/41 (53%), Positives = 28/41 (68%)

Query: 28 DFIQKNYTPYEGDESFLAGATEATTTLWDKVMEGVKLENRT 68
          +FI+ NYT Y GD+SFL G TEATT LW ++ E  K+E   
Sbjct: 1  EFIRLNYTEYLGDDSFLEGPTEATTKLWKELSEKFKVEREK 41


>UniRef50_A5UFY3 Formate acetyltransferase n=1 Tax=Haemophilus influenzae PittGG
          RepID=A5UFY3_HAEIG
          Length = 36

 Score = 55.4 bits (132), Expect = 8e-06,   Method: Composition-based stats.
 Identities = 23/32 (71%), Positives = 23/32 (71%)

Query: 1  MSELNEKLATAWEGFTKGDWQNEVNVRDFIQK 32
          MSELNE    AW GF  GDWQ  VNVRDFIQK
Sbjct: 1  MSELNEMQKLAWAGFAGGDWQENVNVRDFIQK 32


>UniRef50_UPI0001743618 pyruvate formate-lyase n=1 Tax=candidate division TM7 single-cell
           isolate TM7a RepID=UPI0001743618
          Length = 138

 Score = 55.0 bits (131), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 10/59 (16%), Positives = 19/59 (32%), Gaps = 10/59 (16%)

Query: 397 SLQYENDDLMRPDF--------NNDDYAIACCVSPMIVGK-QMQFFG-ARANLAKTMLY 445
                 D+++ P          +  +Y++  CV   + GK   +  G    N  K    
Sbjct: 1   MPAMHTDEIIVPALLNKGVKIEDAYNYSMVGCVEVAVPGKWGYRCTGMTFLNFVKATEL 59


>UniRef50_C6Q339 Putative uncharacterized protein n=1 Tax=Clostridium
          carboxidivorans P7 RepID=C6Q339_9CLOT
          Length = 51

 Score = 55.0 bits (131), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 17/38 (44%), Positives = 22/38 (57%)

Query: 32 KNYTPYEGDESFLAGATEATTTLWDKVMEGVKLENRTH 69
          KNYT YEGD+SFL   TE T  +W +  E +  E +  
Sbjct: 13 KNYTAYEGDKSFLEAPTEKTKKIWKEAEELIVEEIKKE 50


>UniRef50_A6BGV6 Putative uncharacterized protein n=1 Tax=Dorea longicatena DSM
           13814 RepID=A6BGV6_9FIRM
          Length = 43

 Score = 54.2 bits (129), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 13/31 (41%), Positives = 19/31 (61%)

Query: 730 TIRVSGYAVRFNSLTKEQQQDVITRTFTQSM 760
            IRV+GY   F  L K+ Q ++I RT  +S+
Sbjct: 7   LIRVAGYMAYFTELGKDVQDEIIARTEQESL 37


>UniRef50_Q4C1X2 Putative uncharacterized protein n=1 Tax=Crocosphaera watsonii WH
           8501 RepID=Q4C1X2_CROWT
          Length = 99

 Score = 53.4 bits (127), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 23/58 (39%), Positives = 37/58 (63%), Gaps = 4/58 (6%)

Query: 553 GLAIDFEIEGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSN 610
           GLA+D+E+E +YP+FGNND R D +   ++  FM  I+K  TYR      ++L+  ++
Sbjct: 5   GLAVDYEVEEDYPKFGNNDERADTITAKVLSDFMNNIRKNKTYR----QATLLSPFNH 58


>UniRef50_UPI0001742EA8 hypothetical protein cdivTM_08123 n=1 Tax=candidate division TM7
           single-cell isolate TM7a RepID=UPI0001742EA8
          Length = 50

 Score = 45.7 bits (107), Expect = 0.007,   Method: Composition-based stats.
 Identities = 10/46 (21%), Positives = 17/46 (36%), Gaps = 2/46 (4%)

Query: 435 ARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDVLNYDEVMERM 480
              N  K     +N G D +  +Q+    +    D   YD++ E  
Sbjct: 2   TFLNFVKATELVLNDGYDARTGLQLLKAGKL--TDYETYDDLWEAW 45


>UniRef50_UPI00017437D2 hypothetical protein cdivTM_13064 n=1 Tax=candidate division TM7
           single-cell isolate TM7a RepID=UPI00017437D2
          Length = 84

 Score = 44.6 bits (104), Expect = 0.015,   Method: Composition-based stats.
 Identities = 11/64 (17%), Positives = 26/64 (40%), Gaps = 11/64 (17%)

Query: 172 AYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLENG-----------VNLEQTIRL 220
             G G I+ D+++V   G+  ++++  A    +   +  G           +  E TI  
Sbjct: 2   TSGDGHIVPDFKKVLTKGLKGVIEEAKASMEKVDITVYGGYNKIDFLKAVQIVAEATIDF 61

Query: 221 REEI 224
            +++
Sbjct: 62  AQDL 65


>UniRef50_UPI0001742BAE hypothetical protein cdivTM_20712 n=1 Tax=candidate division TM7
           single-cell isolate TM7a RepID=UPI0001742BAE
          Length = 51

 Score = 43.8 bits (102), Expect = 0.027,   Method: Composition-based stats.
 Identities = 10/36 (27%), Positives = 17/36 (47%)

Query: 312 KLRMVRFLRTPEYDELFSGDPIWATESIGGMGLDGR 347
           KL  V  +R+  +    +G P +   +IGG    G+
Sbjct: 11  KLYSVIKVRSTSHSGYGAGYPTYQNVTIGGSTPSGK 46


>UniRef50_C0D5P2 Putative uncharacterized protein (Fragment) n=1 Tax=Clostridium
           asparagiforme DSM 15981 RepID=C0D5P2_9CLOT
          Length = 134

 Score = 43.4 bits (101), Expect = 0.030,   Method: Composition-based stats.
 Identities = 10/40 (25%), Positives = 14/40 (35%), Gaps = 1/40 (2%)

Query: 87  AGYINKQLEKIVGLQTEAPLKRALIPFGGIKMIE-GSCKA 125
           A  + +  E IVG    AP   A  P    + +E      
Sbjct: 95  APLVIQDNELIVGAPCGAPRAGAFSPDIAWRWMEDEIDTI 134


>UniRef50_UPI0001742AB8 putative formate acetyltransferase 3 n=1 Tax=candidate division TM7
           single-cell isolate TM7a RepID=UPI0001742AB8
          Length = 105

 Score = 42.7 bits (99), Expect = 0.052,   Method: Composition-based stats.
 Identities = 12/54 (22%), Positives = 18/54 (33%), Gaps = 4/54 (7%)

Query: 84  SHDAGYINKQLEKIVGLQTEAPLKRALIPFGGIKMI-EGSCK---AYNRELDPM 133
           +H      K  E IVG Q+       L P   +  I +         +R+ D  
Sbjct: 13  THGGAIYIKDGELIVGNQSVDERTAPLFPEYAVDWIVDEINTKGNFDHRDGDKF 66


  Database: uniref50.fasta
    Posted date:  Mar 8, 2010 10:38 AM
  Number of letters in database: 1,040,396,356
  Number of sequences in database:  3,077,464
  
Lambda     K      H
   0.312    0.143    0.389 

Lambda     K      H
   0.267   0.0439    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,226,828,354
Number of Sequences: 3077464
Number of extensions: 168665886
Number of successful extensions: 480482
Number of sequences better than 1.0e-01: 129
Number of HSP's better than  0.1 without gapping: 313
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 478124
Number of HSP's gapped (non-prelim): 447
length of query: 760
length of database: 1,040,396,356
effective HSP length: 137
effective length of query: 623
effective length of database: 618,783,788
effective search space: 385502299924
effective search space used: 385502299924
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.2 bits)
S2: 97 (41.9 bits)
