Phyre 2 Results for P75745

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Email | l.a.kelley@imperial.ac.uk
Description | P75745
Date | Thu Jan 5 12:13:41 GMT 2012
Unique Job ID | 946140ee4e120a9f

Summary |

Top model
Image coloured by rainbow N → C terminus
| Close Jmol

Model (left) based on template c3mmlE_
Top template information
PDB header:hydrolase Chain: E: PDB Molecule:allophanate hydrolase subunit 2; PDBTitle: allophanate hydrolase complex from mycobacterium smegmatis, msmeg0435-2 msmeg0436
Confidence and coverage
Confidence: | 100.0% | Coverage: | 92%
284 residues ( 92% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | L | K | I | I | R | A | G | M | Y | T | T | V | Q | D | G | G | R | H | G | F | R | Q | S | G | I | S | H | C | G | A | L | D | M | P | A | L | R | I | A | N | L | L | V | G | N | D | A | N | A | P | A | L | E | I | T | L | G | Q | L
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? |  |  |  | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | T | V | E | F | E | T | D | G | W | F | A | L | T | G | A | G | C | E | A | R | L | D | D | N | A | V | W | T | G | W | R | L | P | M | K | A | G | Q | R | L | T | L | K | R | P | Q | H | G | M | R | S | Y | L | A | V | A | G | G | I | D
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | V | P | P | V | M | G | S | C | S | T | D | L | K | V | G | I | G | G | L | E | G | R | L | L | K | D | G | D | R | L | P | I | G | K | S | K | R | D | S | M | E | A | Q | G | V | K | Q | L | L | W | G | N | R | I | R | A | L | P | G | P
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  | ? |  |  | ? |  |  |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? |  | ? | ? | ? | ? |  |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240
Sequence |  | E | Y | H | E | F | D | R | A | S | Q | D | A | F | W | R | S | P | W | Q | L | S | S | Q | S | N | R | M | G | Y | R | L | Q | G | Q | I | L | K | R | T | T | D | R | E | L | L | S | H | G | L | L | P | G | V | V | Q | V | P | H | N | G
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? |  | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300
Sequence |  | Q | P | I | V | L | M | N | D | A | Q | T | T | G | G | Y | P | R | I | A | C | I | I | E | A | D | M | Y | H | L | A | Q | I | P | L | G | Q | P | I | H | F | V | Q | C | S | L | E | E | A | L | K | A | R | Q | D | Q | Q | R | Y | F | E
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 310
Sequence |  | Q | L | A | W | R | L | H | N | E | N
Secondary structure |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| c3mmlE_ |

### PDB 3mml chain E

Region: 2 - 290
Aligned: 284
Modelled: 286
Confidence: 100.0%
Identity: 35%
PDB header:hydrolase
Chain: E: PDB Molecule:allophanate hydrolase subunit 2;
PDBTitle: allophanate hydrolase complex from mycobacterium smegmatis, msmeg0435-2 msmeg0436

Phyre2
2 |
| c3oepA_ |

### PDB 3oep chain A

Region: 2 - 281
Aligned: 269
Modelled: 280
Confidence: 100.0%
Identity: 35%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative uncharacterized protein ttha0988;
PDBTitle: crystal structure of ttha0988 in space group p43212

Phyre2
3 |
| c2qf7A_ |

### PDB 2qf7 chain A

Region: 7 - 280
Aligned: 254
Modelled: 274
Confidence: 97.3%
Identity: 8%
PDB header:ligase
Chain: A: PDB Molecule:pyruvate carboxylase protein;
PDBTitle: crystal structure of a complete multifunctional pyruvate carboxylase2 from rhizobium etli

Phyre2
4 |
| c2phcB_ |

### PDB 2phc chain B

Region: 187 - 287
Aligned: 97
Modelled: 100
Confidence: 96.1%
Identity: 15%
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein ph0987;
PDBTitle: crystal structure of conserved uncharacterized protein ph0987 from2 pyrococcus horikoshii

Phyre2
5 |
| d2phcb1 |

### PDB 2phc chain B domain 1

Region: 187 - 287
Aligned: 97
Modelled: 100
Confidence: 95.6%
Identity: 15%
Fold: Cyclophilin-like
Superfamily: Cyclophilin-like
Family: PH0987 C-terminal domain-like

Phyre2
6 |
| c2zp2B_ |

### PDB 2zp2 chain B

Region: 187 - 287
Aligned: 93
Modelled: 100
Confidence: 95.4%
Identity: 16%
PDB header:transferase inhibitor
Chain: B: PDB Molecule:kinase a inhibitor;
PDBTitle: c-terminal domain of kipi from bacillus subtilis

Phyre2
7 |
| c2p0oA_ |

### PDB 2p0o chain A

Region: 148 - 287
Aligned: 130
Modelled: 135
Confidence: 93.8%
Identity: 16%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein duf871;
PDBTitle: crystal structure of a conserved protein from locus ef_2437 in2 enterococcus faecalis with an unknown function

Phyre2
8 |
| c1x7fA_ |

### PDB 1x7f chain A

Region: 148 - 282
Aligned: 132
Modelled: 135
Confidence: 91.9%
Identity: 14%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:outer surface protein;
PDBTitle: crystal structure of an uncharacterized b. cereus protein

Phyre2
9 |
| d1x7fa1 |

### PDB 1x7f chain A domain 1

Region: 173 - 282
Aligned: 106
Modelled: 110
Confidence: 91.9%
Identity: 13%
Fold: Cyclophilin-like
Superfamily: Cyclophilin-like
Family: Outer surface protein, C-terminal domain

Phyre2
10 |
| c3mmlD_ |

### PDB 3mml chain D

Region: 187 - 283
Aligned: 94
Modelled: 93
Confidence: 89.6%
Identity: 15%
PDB header:hydrolase
Chain: D: PDB Molecule:allophanate hydrolase subunit 1;
PDBTitle: allophanate hydrolase complex from mycobacterium smegmatis, msmeg0435-2 msmeg0436

Phyre2
11 |
| c3elsA_ |

### PDB 3els chain A

Region: 80 - 115
Aligned: 36
Modelled: 36
Confidence: 86.3%
Identity: 17%
PDB header:splicing
Chain: A: PDB Molecule:pre-mrna leakage protein 1;
PDBTitle: crystal structure of yeast pml1p, residues 51-204

Phyre2
12 |
| d2piea1 |

### PDB 2pie chain A domain 1

Region: 60 - 127
Aligned: 68
Modelled: 68
Confidence: 84.9%
Identity: 10%
Fold: SMAD/FHA domain
Superfamily: SMAD/FHA domain
Family: FHA domain

Phyre2
13 |
| c1gxcA_ |

### PDB 1gxc chain A

Region: 80 - 113
Aligned: 34
Modelled: 34
Confidence: 81.4%
Identity: 15%
PDB header:phosphoprotein-binding domain
Chain: A: PDB Molecule:serine/threonine-protein kinase chk2;
PDBTitle: fha domain from human chk2 kinase in complex with a2 synthetic phosphopeptide

Phyre2
14 |
| d1gxca_ |

### PDB 1gxc chain A

Region: 80 - 113
Aligned: 34
Modelled: 34
Confidence: 81.4%
Identity: 15%
Fold: SMAD/FHA domain
Superfamily: SMAD/FHA domain
Family: FHA domain

Phyre2
15 |
| c2jkdB_ |

### PDB 2jkd chain B

Region: 51 - 115
Aligned: 61
Modelled: 65
Confidence: 80.1%
Identity: 10%
PDB header:gene regulation
Chain: B: PDB Molecule:pre-mrna leakage protein 1;
PDBTitle: structure of the yeast pml1 splicing factor and its2 integration into the res complex

Phyre2
16 |
| d1uhta_ |

### PDB 1uht chain A

Region: 60 - 106
Aligned: 47
Modelled: 47
Confidence: 69.2%
Identity: 19%
Fold: SMAD/FHA domain
Superfamily: SMAD/FHA domain
Family: FHA domain

Phyre2
17 |
| c2jpeA_ |

### PDB 2jpe chain A

Region: 60 - 106
Aligned: 47
Modelled: 47
Confidence: 68.0%
Identity: 2%
PDB header:transcription
Chain: A: PDB Molecule:nuclear inhibitor of protein phosphatase 1;
PDBTitle: fha domain of nipp1

Phyre2
18 |
| c3gmgB_ |

### PDB 3gmg chain B

Region: 1 - 98
Aligned: 81
Modelled: 98
Confidence: 67.8%
Identity: 21%
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein rv1825/mt1873;
PDBTitle: crystal structure of an uncharacterized conserved protein2 from mycobacterium tuberculosis

Phyre2
19 |
| d2brfa1 |

### PDB 2brf chain A domain 1

Region: 60 - 113
Aligned: 54
Modelled: 54
Confidence: 66.5%
Identity: 13%
Fold: SMAD/FHA domain
Superfamily: SMAD/FHA domain
Family: FHA domain

Phyre2
20 |
| d1ujxa_ |

### PDB 1ujx chain A

Region: 60 - 114
Aligned: 55
Modelled: 55
Confidence: 65.8%
Identity: 7%
Fold: SMAD/FHA domain
Superfamily: SMAD/FHA domain
Family: FHA domain

Phyre2
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Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | c3mmlE_ |
|  | 100.0 | 35 | PDB header:hydrolase Chain: E: PDB Molecule:allophanate hydrolase subunit 2; PDBTitle: allophanate hydrolase complex from mycobacterium smegmatis, msmeg0435-2 msmeg0436
2 | c3oepA_ |
|  | 100.0 | 35 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative uncharacterized protein ttha0988; PDBTitle: crystal structure of ttha0988 in space group p43212
3 | c2qf7A_ |
|  | 97.3 | 8 | PDB header:ligase Chain: A: PDB Molecule:pyruvate carboxylase protein; PDBTitle: crystal structure of a complete multifunctional pyruvate carboxylase2 from rhizobium etli
4 | c2phcB_ |
|  | 96.1 | 15 | PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein ph0987; PDBTitle: crystal structure of conserved uncharacterized protein ph0987 from2 pyrococcus horikoshii
5 | d2phcb1 |
|  | 95.6 | 15 | Fold:Cyclophilin-like Superfamily:Cyclophilin-like Family:PH0987 C-terminal domain-like
6 | c2zp2B_ |
|  | 95.4 | 16 | PDB header:transferase inhibitor Chain: B: PDB Molecule:kinase a inhibitor; PDBTitle: c-terminal domain of kipi from bacillus subtilis
7 | c2p0oA_ |
|  | 93.8 | 16 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein duf871; PDBTitle: crystal structure of a conserved protein from locus ef_2437 in2 enterococcus faecalis with an unknown function
8 | c1x7fA_ |
|  | 91.9 | 14 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:outer surface protein; PDBTitle: crystal structure of an uncharacterized b. cereus protein
9 | d1x7fa1 |
|  | 91.9 | 13 | Fold:Cyclophilin-like Superfamily:Cyclophilin-like Family:Outer surface protein, C-terminal domain
10 | c3mmlD_ |
|  | 89.6 | 15 | PDB header:hydrolase Chain: D: PDB Molecule:allophanate hydrolase subunit 1; PDBTitle: allophanate hydrolase complex from mycobacterium smegmatis, msmeg0435-2 msmeg0436
11 | c3elsA_ |
|  | 86.3 | 17 | PDB header:splicing Chain: A: PDB Molecule:pre-mrna leakage protein 1; PDBTitle: crystal structure of yeast pml1p, residues 51-204
12 | d2piea1 |
|  | 84.9 | 10 | Fold:SMAD/FHA domain Superfamily:SMAD/FHA domain Family:FHA domain
13 | c1gxcA_ |
|  | 81.4 | 15 | PDB header:phosphoprotein-binding domain Chain: A: PDB Molecule:serine/threonine-protein kinase chk2; PDBTitle: fha domain from human chk2 kinase in complex with a2 synthetic phosphopeptide
14 | d1gxca_ |
|  | 81.4 | 15 | Fold:SMAD/FHA domain Superfamily:SMAD/FHA domain Family:FHA domain
15 | c2jkdB_ |
|  | 80.1 | 10 | PDB header:gene regulation Chain: B: PDB Molecule:pre-mrna leakage protein 1; PDBTitle: structure of the yeast pml1 splicing factor and its2 integration into the res complex
16 | d1uhta_ |
|  | 69.2 | 19 | Fold:SMAD/FHA domain Superfamily:SMAD/FHA domain Family:FHA domain
17 | c2jpeA_ |
|  | 68.0 | 2 | PDB header:transcription Chain: A: PDB Molecule:nuclear inhibitor of protein phosphatase 1; PDBTitle: fha domain of nipp1
18 | c3gmgB_ |
|  | 67.8 | 21 | PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein rv1825/mt1873; PDBTitle: crystal structure of an uncharacterized conserved protein2 from mycobacterium tuberculosis
19 | d2brfa1 |
|  | 66.5 | 13 | Fold:SMAD/FHA domain Superfamily:SMAD/FHA domain Family:FHA domain
20 | d1ujxa_ |
|  | 65.8 | 7 | Fold:SMAD/FHA domain Superfamily:SMAD/FHA domain Family:FHA domain
21 | c1yj5C_ |
| not modelled | 62.8 | 11 | PDB header:transferase Chain: C: PDB Molecule:5' polynucleotide kinase-3' phosphatase fha domain; PDBTitle: molecular architecture of mammalian polynucleotide kinase, a dna2 repair enzyme
22 | c3poaA_ |
| not modelled | 62.3 | 10 | PDB header:peptide binding protein Chain: A: PDB Molecule:putative uncharacterized protein tb39.8; PDBTitle: structural and functional analysis of phosphothreonine-dependent fha2 domain interactions
23 | c3kt9A_ |
| not modelled | 61.7 | 16 | PDB header:hydrolase Chain: A: PDB Molecule:aprataxin; PDBTitle: aprataxin fha domain
24 | d1g3ga_ |
| not modelled | 61.5 | 16 | Fold:SMAD/FHA domain Superfamily:SMAD/FHA domain Family:FHA domain
25 | d2g1la1 |
| not modelled | 54.2 | 20 | Fold:SMAD/FHA domain Superfamily:SMAD/FHA domain Family:FHA domain
26 | c3fm8A_ |
| not modelled | 53.9 | 14 | PDB header:transport protein/hydrolase activator Chain: A: PDB Molecule:kinesin-like protein kif13b; PDBTitle: crystal structure of full length centaurin alpha-1 bound with the fha2 domain of kif13b (capri target)
27 | c3kf6B_ |
| not modelled | 47.4 | 20 | PDB header:structural protein Chain: B: PDB Molecule:protein ten1; PDBTitle: crystal structure of s. pombe stn1-ten1 complex
28 | c2eh0A_ |
| not modelled | 47.2 | 12 | PDB header:transport protein Chain: A: PDB Molecule:kinesin-like protein kif1b; PDBTitle: solution structure of the fha domain from human kinesin-2 like protein kif1b
29 | d1g6ga_ |
| not modelled | 46.7 | 15 | Fold:SMAD/FHA domain Superfamily:SMAD/FHA domain Family:FHA domain
30 | d1dmza_ |
| not modelled | 43.4 | 17 | Fold:SMAD/FHA domain Superfamily:SMAD/FHA domain Family:FHA domain
31 | d1kf6b2 |
| not modelled | 41.4 | 6 | Fold:beta-Grasp (ubiquitin-like) Superfamily:2Fe-2S ferredoxin-like Family:2Fe-2S ferredoxin domains from multidomain proteins
32 | d1yjma1 |
| not modelled | 40.1 | 9 | Fold:SMAD/FHA domain Superfamily:SMAD/FHA domain Family:FHA domain
33 | c3hx1B_ |
| not modelled | 38.4 | 10 | PDB header:structural genomics, unknown function Chain: B: PDB Molecule:slr1951 protein; PDBTitle: crystal structure of the slr1951 protein from synechocystis sp.2 northeast structural genomics consortium target sgr167a
34 | c1zeqX_ |
| not modelled | 38.0 | 15 | PDB header:metal binding protein Chain: X: PDB Molecule:cation efflux system protein cusf; PDBTitle: 1.5 a structure of apo-cusf residues 6-88 from escherichia2 coli
35 | c2o55A_ |
| not modelled | 37.6 | 22 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative glycerophosphodiester phosphodiesterase; PDBTitle: crystal structure of a putative glycerophosphodiester2 phosphodiesterase from galdieria sulphuraria
36 | d1dm9a_ |
| not modelled | 36.4 | 11 | Fold:Alpha-L RNA-binding motif Superfamily:Alpha-L RNA-binding motif Family:Heat shock protein 15 kD
37 | c1dm9A_ |
| not modelled | 36.4 | 11 | PDB header:structural genomics Chain: A: PDB Molecule:hypothetical 15.5 kd protein in mrca-pcka PDBTitle: heat shock protein 15 kd
38 | d2cu3a1 |
| not modelled | 34.5 | 13 | Fold:beta-Grasp (ubiquitin-like) Superfamily:MoaD/ThiS Family:ThiS
39 | c2k6pA_ |
| not modelled | 34.2 | 18 | PDB header:unknown function Chain: A: PDB Molecule:uncharacterized protein hp_1423; PDBTitle: solution structure of hypothetical protein, hp1423
40 | c2kklA_ |
| not modelled | 34.0 | 7 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein mb1858; PDBTitle: solution nmr structure of fha domain of mb1858 from2 mycobacterium bovis. northeast structural genomics3 consortium target mbr243c (24-155).
41 | c3ks6A_ |
| not modelled | 30.9 | 18 | PDB header:hydrolase Chain: A: PDB Molecule:glycerophosphoryl diester phosphodiesterase; PDBTitle: crystal structure of putative glycerophosphoryl diester2 phosphodiesterase (17743486) from agrobacterium tumefaciens3 str. c58 (dupont) at 1.80 a resolution
42 | d1nekb2 |
| not modelled | 29.8 | 6 | Fold:beta-Grasp (ubiquitin-like) Superfamily:2Fe-2S ferredoxin-like Family:2Fe-2S ferredoxin domains from multidomain proteins
43 | c2l55A_ |
| not modelled | 29.8 | 14 | PDB header:metal binding protein Chain: A: PDB Molecule:silb,silver efflux protein, mfp component of the three PDBTitle: solution structure of the c-terminal domain of silb from cupriavidus2 metallidurans
44 | c3gqsB_ |
| not modelled | 29.6 | 12 | PDB header:structural genomics, unknown function Chain: B: PDB Molecule:adenylate cyclase-like protein; PDBTitle: crystal structure of the fha domain of ct664 protein from chlamydia2 trachomatis
45 | d1snoa_ |
| not modelled | 28.2 | 19 | Fold:OB-fold Superfamily:Staphylococcal nuclease Family:Staphylococcal nuclease
46 | d2affa1 |
| not modelled | 27.9 | 9 | Fold:SMAD/FHA domain Superfamily:SMAD/FHA domain Family:FHA domain
47 | d2ff4a3 |
| not modelled | 27.6 | 5 | Fold:SMAD/FHA domain Superfamily:SMAD/FHA domain Family:FHA domain
48 | d1w96c1 |
| not modelled | 27.5 | 13 | Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:BC C-terminal domain-like
49 | d1rkna_ |
| not modelled | 26.5 | 17 | Fold:OB-fold Superfamily:Staphylococcal nuclease Family:Staphylococcal nuclease
50 | d1mzka_ |
| not modelled | 26.4 | 9 | Fold:SMAD/FHA domain Superfamily:SMAD/FHA domain Family:FHA domain
51 | c2jqlA_ |
| not modelled | 25.6 | 13 | PDB header:cell cycle Chain: A: PDB Molecule:dna damage response protein kinase dun1; PDBTitle: nmr structure of the yeast dun1 fha domain in complex with2 a doubly phosphorylated (pt) peptide derived from rad533 scd1
52 | c3uotB_ |
| not modelled | 25.6 | 3 | PDB header:cell cycle Chain: B: PDB Molecule:mediator of dna damage checkpoint protein 1; PDBTitle: crystal structure of mdc1 fha domain in complex with a phosphorylated2 peptide from the mdc1 n-terminus
53 | c3rlgA_ |
| not modelled | 25.3 | 11 | PDB header:hydrolase Chain: A: PDB Molecule:sphingomyelin phosphodiesterase d lisictox-alphaia1a; PDBTitle: crystal structure of loxosceles intermedia phospholipase d isoform 12 h12a mutant
54 | d1zud21 |
| not modelled | 24.7 | 14 | Fold:beta-Grasp (ubiquitin-like) Superfamily:MoaD/ThiS Family:ThiS
55 | c2zplA_ |
| not modelled | 24.3 | 26 | PDB header:hydrolase Chain: A: PDB Molecule:regulator of sigma e protease; PDBTitle: crystal structure analysis of pdz domain a
56 | d2oyza1 |
| not modelled | 24.2 | 12 | Fold:Double-stranded beta-helix Superfamily:RmlC-like cupins Family:VPA0057-like
57 | c1r21A_ |
| not modelled | 23.9 | 9 | PDB header:cell cycle Chain: A: PDB Molecule:antigen ki-67; PDBTitle: solution structure of human ki67 fha domain
58 | d1lgpa_ |
| not modelled | 22.9 | 10 | Fold:SMAD/FHA domain Superfamily:SMAD/FHA domain Family:FHA domain
59 | c3rggD_ |
| not modelled | 22.9 | 28 | PDB header:lyase Chain: D: PDB Molecule:phosphoribosylaminoimidazole carboxylase, pure protein; PDBTitle: crystal structure of treponema denticola pure bound to air
60 | d2bs2b2 |
| not modelled | 22.6 | 13 | Fold:beta-Grasp (ubiquitin-like) Superfamily:2Fe-2S ferredoxin-like Family:2Fe-2S ferredoxin domains from multidomain proteins
61 | c2g1eA_ |
| not modelled | 22.5 | 15 | PDB header:transferase Chain: A: PDB Molecule:hypothetical protein ta0895; PDBTitle: solution structure of ta0895
62 | c2kl0A_ |
| not modelled | 22.4 | 24 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative thiamin biosynthesis this; PDBTitle: solution nmr structure of rhodopseudomonas palustris rpa3574,2 northeast structural genomics consortium (nesg) target rpr325
63 | c2nnzA_ |
| not modelled | 21.5 | 13 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein; PDBTitle: solution structure of the hypothetical protein af2241 from2 archaeoglobus fulgidus
64 | c3eo6B_ |
| not modelled | 21.2 | 17 | PDB header:structural genomics, unknown function Chain: B: PDB Molecule:protein of unknown function (duf1255); PDBTitle: crystal structure of protein of unknown function (duf1255)2 (afe_2634) from acidithiobacillus ferrooxidans ncib8455 at3 0.97 a resolution
65 | d1wlna1 |
| not modelled | 21.0 | 12 | Fold:SMAD/FHA domain Superfamily:SMAD/FHA domain Family:FHA domain
66 | d1k92a1 |
| not modelled | 21.0 | 33 | Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases
67 | c3cwiA_ |
| not modelled | 20.5 | 13 | PDB header:biosynthetic protein Chain: A: PDB Molecule:thiamine-biosynthesis protein this; PDBTitle: crystal structure of thiamine biosynthesis protein (this)2 from geobacter metallireducens. northeast structural3 genomics consortium target gmr137
68 | c3rleA_ |
| not modelled | 20.5 | 33 | PDB header:membrane protein Chain: A: PDB Molecule:golgi reassembly-stacking protein 2; PDBTitle: crystal structure of grasp55 grasp domain (residues 7-208)
69 | d2z1ca1 |
| not modelled | 18.9 | 9 | Fold:OB-fold Superfamily:HupF/HypC-like Family:HupF/HypC-like
70 | d1v10a2 |
| not modelled | 17.7 | 13 | Fold:Cupredoxin-like Superfamily:Cupredoxins Family:Multidomain cupredoxins
71 | c3i10A_ |
| not modelled | 16.9 | 31 | PDB header:hydrolase Chain: A: PDB Molecule:putative glycerophosphoryl diester phosphodiesterase; PDBTitle: crystal structure of putative glycerophosphoryl diester2 phosphodiesterase (np_812074.1) from bacteroides thetaiotaomicron3 vpi-5482 at 1.35 a resolution
72 | c2jrtA_ |
| not modelled | 16.4 | 23 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: nmr solution structure of the protein coded by gene2 rhos4_12090 of rhodobacter sphaeroides. northeast3 structural genomics target rhr5
73 | d2soba_ |
| not modelled | 15.9 | 16 | Fold:OB-fold Superfamily:Staphylococcal nuclease Family:Staphylococcal nuclease
74 | c3hvzB_ |
| not modelled | 15.0 | 23 | PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of the tgs domain of the clolep_03100 protein from2 clostridium leptum, northeast structural genomics consortium target3 qlr13a
75 | c3ju0A_ |
| not modelled | 14.8 | 38 | PDB header:dna binding protein Chain: A: PDB Molecule:phage integrase; PDBTitle: structure of the arm-type binding domain of hai7 integrase
76 | d1u1ha1 |
| not modelled | 14.6 | 44 | Fold:TIM beta/alpha-barrel Superfamily:UROD/MetE-like Family:Cobalamin-independent methionine synthase
77 | c3r6oA_ |
| not modelled | 14.3 | 30 | PDB header:isomerase Chain: A: PDB Molecule:2-hydroxyhepta-2,4-diene-1, 7-dioateisomerase; PDBTitle: crystal structure of a probable 2-hydroxyhepta-2,4-diene-1, 7-2 dioateisomerase from mycobacterium abscessus
78 | d1zcca1 |
| not modelled | 14.1 | 23 | Fold:TIM beta/alpha-barrel Superfamily:PLC-like phosphodiesterases Family:Glycerophosphoryl diester phosphodiesterase
79 | c2aanA_ |
| not modelled | 13.9 | 17 | PDB header:electron transport Chain: A: PDB Molecule:auracyanin a; PDBTitle: auracyanin a: a "blue" copper protein from the green thermophilic2 photosynthetic bacterium,chloroflexus aurantiacus
80 | d2pyta1 |
| not modelled | 13.7 | 13 | Fold:Double-stranded beta-helix Superfamily:RmlC-like cupins Family:EutQ-like
81 | d1tygb_ |
| not modelled | 13.7 | 3 | Fold:beta-Grasp (ubiquitin-like) Superfamily:MoaD/ThiS Family:ThiS
82 | d2bh1x1 |
| not modelled | 13.5 | 13 | Fold:Alpha-lytic protease prodomain-like Superfamily:EspE N-terminal domain-like Family:GSPII protein E N-terminal domain-like
83 | c2bh1Y_ |
| not modelled | 13.5 | 13 | PDB header:transport protein Chain: Y: PDB Molecule:general secretion pathway protein e,; PDBTitle: x-ray structure of the general secretion pathway complex of2 the n-terminal domain of epse and the cytosolic domain of3 epsl of vibrio cholerae
84 | c3rlhA_ |
| not modelled | 13.4 | 13 | PDB header:hydrolase Chain: A: PDB Molecule:sphingomyelin phosphodiesterase d lisictox-alphaia1a; PDBTitle: crystal structure of a class ii phospholipase d from loxosceles2 intermedia venom
85 | d1tkea1 |
| not modelled | 13.3 | 13 | Fold:beta-Grasp (ubiquitin-like) Superfamily:TGS-like Family:TGS domain
86 | d1nyra2 |
| not modelled | 13.3 | 9 | Fold:beta-Grasp (ubiquitin-like) Superfamily:TGS-like Family:TGS domain
87 | c2vgmA_ |
| not modelled | 13.2 | 17 | PDB header:cell cycle Chain: A: PDB Molecule:dom34; PDBTitle: structure of yeast dom34 : a protein related to translation2 termination factor erf1 and involved in no-go decay.
88 | c1kh2D_ |
| not modelled | 13.0 | 35 | PDB header:ligase Chain: D: PDB Molecule:argininosuccinate synthetase; PDBTitle: crystal structure of thermus thermophilus hb82 argininosuccinate synthetase in complex with atp
89 | c1tygG_ |
| not modelled | 12.8 | 0 | PDB header:biosynthetic protein Chain: G: PDB Molecule:yjbs; PDBTitle: structure of the thiazole synthase/this complex
90 | c3rpfB_ |
| not modelled | 12.8 | 13 | PDB header:transferase Chain: B: PDB Molecule:molybdopterin synthase catalytic subunit; PDBTitle: protein-protein complex of subunit 1 and 2 of molybdopterin-converting2 factor from helicobacter pylori 26695
91 | d1j20a1 |
| not modelled | 12.5 | 35 | Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases
92 | c3hqxA_ |
| not modelled | 12.4 | 16 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:upf0345 protein aciad0356; PDBTitle: crystal structure of protein of unknown function (duf1255,pf06865)2 from acinetobacter sp. adp1
93 | d2oa4a1 |
| not modelled | 12.4 | 25 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:TrpR-like Family:SPO1678-like
94 | d1vl2a1 |
| not modelled | 12.0 | 31 | Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases
95 | c2zpmA_ |
| not modelled | 12.0 | 18 | PDB header:hydrolase Chain: A: PDB Molecule:regulator of sigma e protease; PDBTitle: crystal structure analysis of pdz domain b
96 | c2x4iA_ |
| not modelled | 11.6 | 6 | PDB header:unknown function Chain: A: PDB Molecule:uncharacterized protein 114; PDBTitle: orf 114a from sulfolobus islandicus rudivirus 1
97 | c3r7kB_ |
| not modelled | 11.6 | 13 | PDB header:oxidoreductase Chain: B: PDB Molecule:probable acyl coa dehydrogenase; PDBTitle: crystal structure of a probable acyl coa dehydrogenase from2 mycobacterium abscessus atcc 19977 / dsm 44196
98 | d1tt2a_ |
| not modelled | 11.5 | 19 | Fold:OB-fold Superfamily:Staphylococcal nuclease Family:Staphylococcal nuclease
99 | c3no3A_ |
| not modelled | 11.5 | 21 | PDB header:hydrolase Chain: A: PDB Molecule:glycerophosphodiester phosphodiesterase; PDBTitle: crystal structure of a glycerophosphodiester phosphodiesterase2 (bdi_0402) from parabacteroides distasonis atcc 8503 at 1.89 a3 resolution

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0