Phyre 2 Results for P45848

Phyre Home | Retrieve Phyre Job Id

Email | l.a.kelley@imperial.ac.uk
Description | P45848
Date | Thu Jan 5 12:03:51 GMT 2012
Unique Job ID | 93f9ac25c7956663

Summary |

Top model
Image coloured by rainbow N → C terminus
| Close Jmol

Model (left) based on template c3kd4A_
Top template information
PDB header:hydrolase Chain: A: PDB Molecule:putative protease; PDBTitle: crystal structure of a putative protease (bdi_1141) from2 parabacteroides distasonis atcc 8503 at 2.00 a resolution
Confidence and coverage
Confidence: | 87.5% | Coverage: | 27%
168 residues ( 27% of your sequence) have been modelled with 87.5% confidence by the single highest scoring template.
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3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | A | G | K | F | R | C | I | L | L | L | I | A | G | L | F | V | S | S | L | S | Y | A | E | N | T | E | I | P | S | Y | E | E | G | I | S | L | F | D | V | E | A | T | L | Q | P | D | G | V | L | D | I | K | E | N | I | H | F | Q | A
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | R | N | Q | Q | I | K | H | G | F | Y | R | D | L | P | R | L | W | M | Q | P | D | G | D | A | A | L | L | N | Y | H | I | V | G | V | T | R | D | G | I | P | E | P | W | H | L | D | W | H | I | G | L | M | S | I | V | V | G | D | K | Q
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | R | F | L | P | Q | G | D | Y | H | Y | Q | I | H | Y | Q | V | K | N | A | F | L | R | E | G | D | S | D | L | L | I | W | N | V | T | G | N | H | W | P | F | E | I | Y | K | T | R | F | S | L | Q | F | S | N | I | A | G | N | P | F | S
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240
Sequence |  | E | I | D | L | F | T | G | E | E | G | D | T | Y | R | N | G | R | I | L | E | D | G | R | I | E | S | R | D | P | F | Y | R | E | D | F | T | V | L | Y | R | W | P | H | A | L | L | S | N | A | S | A | P | Q | T | T | N | I | F | S | H
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300
Sequence |  | L | L | L | P | S | T | S | S | L | L | I | W | F | P | C | L | F | L | V | C | G | W | L | Y | L | W | K | R | R | P | Q | F | T | P | V | D | V | I | E | T | D | V | I | P | P | D | Y | T | P | G | M | L | R | L | D | A | K | L | V | Y
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360
Sequence |  | D | D | K | G | F | C | A | D | I | V | N | L | I | V | K | G | K | I | H | L | E | D | Q | S | D | K | N | Q | Q | I | L | I | R | V | N | E | G | A | T | R | N | N | A | V | L | L | P | A | E | Q | L | L | L | E | A | L | F | R | K | G
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  | ? | ? | ? |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420
Sequence |  | D | K | V | V | L | T | G | R | R | N | R | V | L | R | R | A | F | L | R | M | Q | K | F | Y | L | P | R | K | K | S | S | F | Y | R | S | D | T | F | L | Q | W | G | G | L | A | I | L | A | V | I | L | Y | G | N | L | S | P | V | G | W
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? |  |  |  |  |  |  | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480
Sequence |  | A | G | M | S | L | V | G | D | M | F | I | M | I | C | W | I | I | P | F | L | F | C | S | L | E | L | L | F | A | R | D | D | D | K | P | C | V | N | R | V | I | I | T | L | F | L | P | L | I | C | S | G | V | A | F | Y | S | L | Y | I
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540
Sequence |  | N | V | G | D | V | F | F | Y | W | Y | M | P | A | G | Y | F | T | A | V | C | L | T | G | Y | L | T | G | M | G | Y | I | F | L | P | K | F | T | Q | T | G | Q | Q | R | Y | A | H | G | E | A | I | V | N | Y | L | A | R | K | E | A | A
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600
Sequence |  | T | H | S | G | R | R | R | K | G | E | T | R | K | L | D | Y | A | L | L | G | W | A | I | S | A | N | L | G | R | E | W | A | L | R | I | A | P | S | L | S | S | A | I | R | A | P | E | I | A | R | N | G | V | L | F | S | L | Q | T | H
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | .
Sequence |  | L | S | C | G | A | N | T | S | L | L | G | R | S | Y | S | G | G | G | A | G | G | G | A | G | G | G | G | G | G | G | W
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| c3kd4A_ |

### PDB 3kd4 chain A

Region: 32 - 211
Aligned: 168
Modelled: 180
Confidence: 87.5%
Identity: 9%
PDB header:hydrolase
Chain: A: PDB Molecule:putative protease;
PDBTitle: crystal structure of a putative protease (bdi_1141) from2 parabacteroides distasonis atcc 8503 at 2.00 a resolution

Phyre2
2 |
| d3b7sa2 |

### PDB 3b7s chain A domain 2

Region: 33 - 138
Aligned: 92
Modelled: 93
Confidence: 72.1%
Identity: 9%
Fold: Leukotriene A4 hydrolase N-terminal domain
Superfamily: Leukotriene A4 hydrolase N-terminal domain
Family: Leukotriene A4 hydrolase N-terminal domain

Phyre2
3 |
| c3ebhA_ |

### PDB 3ebh chain A

Region: 26 - 171
Aligned: 130
Modelled: 133
Confidence: 71.9%
Identity: 5%
PDB header:hydrolase inhibitor
Chain: A: PDB Molecule:m1 family aminopeptidase;
PDBTitle: structure of the m1 alanylaminopeptidase from malaria complexed with2 bestatin

Phyre2
4 |
| c3b7uX_ |

### PDB 3b7u chain X

Region: 34 - 137
Aligned: 90
Modelled: 90
Confidence: 61.6%
Identity: 10%
PDB header:hydrolase
Chain: X: PDB Molecule:leukotriene a-4 hydrolase;
PDBTitle: leukotriene a4 hydrolase complexed with kelatorphan

Phyre2
5 |
| c2gtqA_ |

### PDB 2gtq chain A

Region: 26 - 171
Aligned: 121
Modelled: 130
Confidence: 52.9%
Identity: 12%
PDB header:hydrolase
Chain: A: PDB Molecule:aminopeptidase n;
PDBTitle: crystal structure of aminopeptidase n from human pathogen neisseria2 meningitidis

Phyre2
6 |
| c3ciaA_ |

### PDB 3cia chain A

Region: 32 - 171
Aligned: 116
Modelled: 121
Confidence: 51.5%
Identity: 9%
PDB header:hydrolase
Chain: A: PDB Molecule:cold-active aminopeptidase;
PDBTitle: crystal structure of cold-aminopeptidase from colwellia2 psychrerythraea

Phyre2
7 |
| c2xpyA_ |

### PDB 2xpy chain A

Region: 32 - 174
Aligned: 126
Modelled: 143
Confidence: 35.6%
Identity: 10%
PDB header:hydrolase
Chain: A: PDB Molecule:leukotriene a-4 hydrolase;
PDBTitle: structure of native leukotriene a4 hydrolase from saccharomyces2 cerevisiae

Phyre2
8 |
| d2etha1 |

### PDB 2eth chain A domain 1

Region: 285 - 387
Aligned: 96
Modelled: 103
Confidence: 33.5%
Identity: 13%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: "Winged helix" DNA-binding domain
Family: MarR-like transcriptional regulators

Phyre2
9 |
| d1tkna_ |

### PDB 1tkn chain A

Region: 527 - 559
Aligned: 26
Modelled: 33
Confidence: 28.9%
Identity: 12%
Fold: STAT-like
Superfamily: CAPPD, an extracellular domain of amyloid beta A4 protein
Family: CAPPD, an extracellular domain of amyloid beta A4 protein

Phyre2
10 |
| d1lj9a_ |

### PDB 1lj9 chain A

Region: 285 - 389
Aligned: 98
Modelled: 105
Confidence: 26.4%
Identity: 16%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: "Winged helix" DNA-binding domain
Family: MarR-like transcriptional regulators

Phyre2
11 |
| d2fbha1 |

### PDB 2fbh chain A domain 1

Region: 284 - 386
Aligned: 96
Modelled: 103
Confidence: 22.9%
Identity: 10%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: "Winged helix" DNA-binding domain
Family: MarR-like transcriptional regulators

Phyre2
12 |
| c3hd7A_ |

### PDB 3hd7 chain A

Region: 353 - 418
Aligned: 66
Modelled: 66
Confidence: 21.8%
Identity: 8%
PDB header:exocytosis
Chain: A: PDB Molecule:vesicle-associated membrane protein 2;
PDBTitle: helical extension of the neuronal snare complex into the membrane,2 spacegroup c 1 2 1

Phyre2
13 |
| c3se6A_ |

### PDB 3se6 chain A

Region: 36 - 220
Aligned: 170
Modelled: 183
Confidence: 19.7%
Identity: 12%
PDB header:hydrolase
Chain: A: PDB Molecule:endoplasmic reticulum aminopeptidase 2;
PDBTitle: crystal structure of the human endoplasmic reticulum aminopeptidase 2

Phyre2
14 |
| c2i7uA_ |

### PDB 2i7u chain A

Region: 624 - 630
Aligned: 7
Modelled: 6
Confidence: 19.5%
Identity: 100%
PDB header:de novo protein/ligand binding protein
Chain: A: PDB Molecule:four-alpha-helix bundle;
PDBTitle: structural and dynamical analysis of a four-alpha-helix2 bundle with designed anesthetic binding pockets

Phyre2
15 |
| c3nrvC_ |

### PDB 3nrv chain C

Region: 285 - 386
Aligned: 95
Modelled: 102
Confidence: 18.3%
Identity: 13%
PDB header:transcription regulator
Chain: C: PDB Molecule:putative transcriptional regulator (marr/emrr family);
PDBTitle: crystal structure of marr/emrr family transcriptional regulator from2 acinetobacter sp. adp1

Phyre2
16 |
| d2a61a1 |

### PDB 2a61 chain A domain 1

Region: 285 - 388
Aligned: 97
Modelled: 104
Confidence: 17.9%
Identity: 9%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: "Winged helix" DNA-binding domain
Family: MarR-like transcriptional regulators

Phyre2
17 |
| c2rngA_ |

### PDB 2rng chain A

Region: 577 - 621
Aligned: 45
Modelled: 45
Confidence: 16.8%
Identity: 13%
PDB header:antimicrobial protein
Chain: A: PDB Molecule:big defensin;
PDBTitle: solution structure of big defensin

Phyre2
18 |
| c3g3zA_ |

### PDB 3g3z chain A

Region: 285 - 391
Aligned: 100
Modelled: 107
Confidence: 15.3%
Identity: 12%
PDB header:transcription
Chain: A: PDB Molecule:transcriptional regulator, marr family;
PDBTitle: the structure of nmb1585, a marr family regulator from neisseria2 meningitidis

Phyre2
19 |
| c2rh0B_ |

### PDB 2rh0 chain B

Region: 158 - 184
Aligned: 27
Modelled: 27
Confidence: 14.9%
Identity: 11%
PDB header:nuclear protein
Chain: B: PDB Molecule:nudc domain-containing protein 2;
PDBTitle: crystal structure of nudc domain-containing protein 22 (13542905) from mus musculus at 1.95 a resolution

Phyre2
20 |
| d1xp8a2 |

### PDB 1xp8 chain A domain 2

Region: 574 - 598
Aligned: 25
Modelled: 25
Confidence: 12.0%
Identity: 16%
Fold: Anti-LPS factor/recA domain
Superfamily: RecA protein, C-terminal domain
Family: RecA protein, C-terminal domain

Phyre2
21 |
22 |
23 |
24 |
25 |
26 |
27 |
28 |
29 |
30 |
31 |
32 |
33 |
34 |
35 |
36 |
37 |
38 |
39 |
40 |
41 |
42 |
43 |
44 |
45 |
46 |
47 |
48 |
49 |
50 |
51 |
52 |
53 |
54 |
55 |
56 |
57 |
58 |

Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | c3kd4A_ |
|  | 87.5 | 9 | PDB header:hydrolase Chain: A: PDB Molecule:putative protease; PDBTitle: crystal structure of a putative protease (bdi_1141) from2 parabacteroides distasonis atcc 8503 at 2.00 a resolution
2 | d3b7sa2 |
|  | 72.1 | 9 | Fold:Leukotriene A4 hydrolase N-terminal domain Superfamily:Leukotriene A4 hydrolase N-terminal domain Family:Leukotriene A4 hydrolase N-terminal domain
3 | c3ebhA_ |
|  | 71.9 | 5 | PDB header:hydrolase inhibitor Chain: A: PDB Molecule:m1 family aminopeptidase; PDBTitle: structure of the m1 alanylaminopeptidase from malaria complexed with2 bestatin
4 | c3b7uX_ |
|  | 61.6 | 10 | PDB header:hydrolase Chain: X: PDB Molecule:leukotriene a-4 hydrolase; PDBTitle: leukotriene a4 hydrolase complexed with kelatorphan
5 | c2gtqA_ |
|  | 52.9 | 12 | PDB header:hydrolase Chain: A: PDB Molecule:aminopeptidase n; PDBTitle: crystal structure of aminopeptidase n from human pathogen neisseria2 meningitidis
6 | c3ciaA_ |
|  | 51.5 | 9 | PDB header:hydrolase Chain: A: PDB Molecule:cold-active aminopeptidase; PDBTitle: crystal structure of cold-aminopeptidase from colwellia2 psychrerythraea
7 | c2xpyA_ |
|  | 35.6 | 10 | PDB header:hydrolase Chain: A: PDB Molecule:leukotriene a-4 hydrolase; PDBTitle: structure of native leukotriene a4 hydrolase from saccharomyces2 cerevisiae
8 | d2etha1 |
|  | 33.5 | 13 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:MarR-like transcriptional regulators
9 | d1tkna_ |
|  | 28.9 | 12 | Fold:STAT-like Superfamily:CAPPD, an extracellular domain of amyloid beta A4 protein Family:CAPPD, an extracellular domain of amyloid beta A4 protein
10 | d1lj9a_ |
|  | 26.4 | 16 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:MarR-like transcriptional regulators
11 | d2fbha1 |
|  | 22.9 | 10 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:MarR-like transcriptional regulators
12 | c3hd7A_ |
|  | 21.8 | 8 | PDB header:exocytosis Chain: A: PDB Molecule:vesicle-associated membrane protein 2; PDBTitle: helical extension of the neuronal snare complex into the membrane,2 spacegroup c 1 2 1
13 | c3se6A_ |
|  | 19.7 | 12 | PDB header:hydrolase Chain: A: PDB Molecule:endoplasmic reticulum aminopeptidase 2; PDBTitle: crystal structure of the human endoplasmic reticulum aminopeptidase 2
14 | c2i7uA_ |
|  | 19.5 | 100 | PDB header:de novo protein/ligand binding protein Chain: A: PDB Molecule:four-alpha-helix bundle; PDBTitle: structural and dynamical analysis of a four-alpha-helix2 bundle with designed anesthetic binding pockets
15 | c3nrvC_ |
|  | 18.3 | 13 | PDB header:transcription regulator Chain: C: PDB Molecule:putative transcriptional regulator (marr/emrr family); PDBTitle: crystal structure of marr/emrr family transcriptional regulator from2 acinetobacter sp. adp1
16 | d2a61a1 |
|  | 17.9 | 9 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:MarR-like transcriptional regulators
17 | c2rngA_ |
|  | 16.8 | 13 | PDB header:antimicrobial protein Chain: A: PDB Molecule:big defensin; PDBTitle: solution structure of big defensin
18 | c3g3zA_ |
|  | 15.3 | 12 | PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator, marr family; PDBTitle: the structure of nmb1585, a marr family regulator from neisseria2 meningitidis
19 | c2rh0B_ |
|  | 14.9 | 11 | PDB header:nuclear protein Chain: B: PDB Molecule:nudc domain-containing protein 2; PDBTitle: crystal structure of nudc domain-containing protein 22 (13542905) from mus musculus at 1.95 a resolution
20 | d1xp8a2 |
|  | 12.0 | 16 | Fold:Anti-LPS factor/recA domain Superfamily:RecA protein, C-terminal domain Family:RecA protein, C-terminal domain
21 | d1s3ja_ |
| not modelled | 11.1 | 7 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:MarR-like transcriptional regulators
22 | c3bj6B_ |
| not modelled | 11.0 | 11 | PDB header:transcription regulator Chain: B: PDB Molecule:transcriptional regulator, marr family; PDBTitle: crystal structure of marr family transcription regulator sp03579
23 | d1rw6a_ |
| not modelled | 10.9 | 12 | Fold:STAT-like Superfamily:CAPPD, an extracellular domain of amyloid beta A4 protein Family:CAPPD, an extracellular domain of amyloid beta A4 protein
24 | c3k66A_ |
| not modelled | 10.6 | 19 | PDB header:cell adhesion Chain: A: PDB Molecule:beta-amyloid-like protein; PDBTitle: x-ray crystal structure of the e2 domain of c. elegans apl-1
25 | c3bogC_ |
| not modelled | 10.3 | 87 | PDB header:antifreeze protein Chain: C: PDB Molecule:6.5 kda glycine-rich antifreeze protein; PDBTitle: snow flea antifreeze protein quasi-racemate
26 | c3bogD_ |
| not modelled | 10.3 | 87 | PDB header:antifreeze protein Chain: D: PDB Molecule:6.5 kda glycine-rich antifreeze protein; PDBTitle: snow flea antifreeze protein quasi-racemate
27 | c1z5hB_ |
| not modelled | 10.2 | 12 | PDB header:hydrolase Chain: B: PDB Molecule:tricorn protease interacting factor f3; PDBTitle: crystal structures of the tricorn interacting factor f32 from thermoplasma acidophilum
28 | c3bjaA_ |
| not modelled | 9.7 | 11 | PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional regulator, marr family, putative; PDBTitle: crystal structure of putative marr-like transcription regulator2 (np_978771.1) from bacillus cereus atcc 10987 at 2.38 a resolution
29 | c3ju0A_ |
| not modelled | 9.6 | 18 | PDB header:dna binding protein Chain: A: PDB Molecule:phage integrase; PDBTitle: structure of the arm-type binding domain of hai7 integrase
30 | c2zouB_ |
| not modelled | 9.2 | 21 | PDB header:cell adhesion Chain: B: PDB Molecule:spondin-1; PDBTitle: crystal struture of human f-spondin reeler domain (fragment 2)
31 | c2vn2B_ |
| not modelled | 9.0 | 19 | PDB header:replication Chain: B: PDB Molecule:chromosome replication initiation protein; PDBTitle: crystal structure of the n-terminal domain of dnad protein2 from geobacillus kaustophilus hta426
32 | d2v9va2 |
| not modelled | 7.9 | 15 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:C-terminal fragment of elongation factor SelB
33 | c3cwcB_ |
| not modelled | 7.8 | 35 | PDB header:transferase Chain: B: PDB Molecule:putative glycerate kinase 2; PDBTitle: crystal structure of putative glycerate kinase 2 from salmonella2 typhimurium lt2
34 | c3jtzA_ |
| not modelled | 7.4 | 21 | PDB header:dna binding protein Chain: A: PDB Molecule:integrase; PDBTitle: structure of the arm-type binding domain of hpi integrase
35 | c1cn3F_ |
| not modelled | 7.1 | 88 | PDB header:viral protein Chain: F: PDB Molecule:fragment of coat protein vp2; PDBTitle: interaction of polyomavirus internal protein vp2 with major2 capsid protein vp1 and implications for participation of3 vp2 in viral entry
36 | c2fl8N_ |
| not modelled | 6.6 | 10 | PDB header:virus/viral protein Chain: N: PDB Molecule:baseplate structural protein gp10; PDBTitle: fitting of the gp10 trimer structure into the cryoem map of the2 bacteriophage t4 baseplate in the hexagonal conformation.
37 | c2pqnB_ |
| not modelled | 6.6 | 27 | PDB header:apoptosis Chain: B: PDB Molecule:mitochondrial division protein 1; PDBTitle: crystal structure of yeast fis1 complexed with a fragment of yeast2 mdv1
38 | c3c5pF_ |
| not modelled | 6.6 | 16 | PDB header:structural genomics, unknown function Chain: F: PDB Molecule:protein bas0735 of unknown function; PDBTitle: crystal structure of bas0735, a protein of unknown function from2 bacillus anthracis str. sterne
39 | c3cooB_ |
| not modelled | 6.4 | 21 | PDB header:cell adhesion Chain: B: PDB Molecule:spondin-1; PDBTitle: the crystal structure of reelin-n domain of f-spondin
40 | c2oq0D_ |
| not modelled | 6.3 | 16 | PDB header:protein binding Chain: D: PDB Molecule:gamma-interferon-inducible protein ifi-16; PDBTitle: crystal structure of the first hin-200 domain of interferon-inducible2 protein 16
41 | c3pa8A_ |
| not modelled | 6.2 | 9 | PDB header:toxin/peptide inhibitor Chain: A: PDB Molecule:toxin b; PDBTitle: structure of the c. difficile tcdb cysteine protease domain in complex2 with a peptide inhibitor
42 | c2l3nA_ |
| not modelled | 6.2 | 53 | PDB header:dna binding protein Chain: A: PDB Molecule:dna-binding protein rap1, telomere length regulator taz1; PDBTitle: solution structure of rap1-taz1 fusion protein
43 | c2rddB_ |
| not modelled | 6.0 | 7 | PDB header:membrane protein/transport protein Chain: B: PDB Molecule:upf0092 membrane protein yajc; PDBTitle: x-ray crystal structure of acrb in complex with a novel2 transmembrane helix.
44 | c2khuA_ |
| not modelled | 6.0 | 25 | PDB header:transferase/protein binding Chain: A: PDB Molecule:immunoglobulin g-binding protein g, dna PDBTitle: solution structure of the ubiquitin-binding motif of human2 polymerase iota
45 | c2l0gA_ |
| not modelled | 5.9 | 25 | PDB header:protein binding Chain: A: PDB Molecule:dna polymerase iota; PDBTitle: solution nmr structure of ubiquitin-binding motif (ubm2) of human2 polymerase iota
46 | c3pmrB_ |
| not modelled | 5.9 | 27 | PDB header:cell adhesion Chain: B: PDB Molecule:amyloid-like protein 1; PDBTitle: crystal structure of e2 domain of human amyloid precursor-like protein2 1
47 | d2hyma1 |
| not modelled | 5.8 | 9 | Fold:Immunoglobulin-like beta-sandwich Superfamily:Fibronectin type III Family:Fibronectin type III
48 | c2nnnB_ |
| not modelled | 5.8 | 12 | PDB header:transcription Chain: B: PDB Molecule:probable transcriptional regulator; PDBTitle: crystal structure of probable transcriptional regulator from2 pseudomonas aeruginosa
49 | d1wfia_ |
| not modelled | 5.6 | 7 | Fold:HSP20-like chaperones Superfamily:HSP20-like chaperones Family:Nuclear movement domain
50 | c3n39D_ |
| not modelled | 5.5 | 14 | PDB header:oxidoreductase Chain: D: PDB Molecule:protein nrdi; PDBTitle: ribonucleotide reductase dimanganese(ii)-nrdf from escherichia coli in2 complex with nrdi
51 | c2x8kB_ |
| not modelled | 5.3 | 12 | PDB header:viral protein Chain: B: PDB Molecule:hypothetical protein 19.1; PDBTitle: crystal structure of spp1 dit (gp 19.1) protein, a paradigm2 of hub adsorption apparatus in gram-positive infecting3 phages.
52 | c2o30A_ |
| not modelled | 5.3 | 9 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:nuclear movement protein; PDBTitle: nuclear movement protein from e. cuniculi gb-m1
53 | c2kncA_ |
| not modelled | 5.3 | 18 | PDB header:cell adhesion Chain: A: PDB Molecule:integrin alpha-iib; PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex
54 | c2jo1A_ |
| not modelled | 5.3 | 23 | PDB header:hydrolase regulator Chain: A: PDB Molecule:phospholemman; PDBTitle: structure of the na,k-atpase regulatory protein fxyd1 in2 micelles
55 | c1kn7A_ |
| not modelled | 5.2 | 30 | PDB header:membrane protein Chain: A: PDB Molecule:voltage-gated potassium channel protein kv1.4; PDBTitle: solution structure of the tandem inactivation domain2 (residues 1-75) of potassium channel rck4 (kv1.4)
56 | d1ubea2 |
| not modelled | 5.2 | 16 | Fold:Anti-LPS factor/recA domain Superfamily:RecA protein, C-terminal domain Family:RecA protein, C-terminal domain
57 | d1mo6a2 |
| not modelled | 5.1 | 16 | Fold:Anti-LPS factor/recA domain Superfamily:RecA protein, C-terminal domain Family:RecA protein, C-terminal domain
58 | c2qwwB_ |
| not modelled | 5.0 | 13 | PDB header:transcription Chain: B: PDB Molecule:transcriptional regulator, marr family; PDBTitle: crystal structure of multiple antibiotic-resistance repressor (marr)2 (yp_013417.1) from listeria monocytogenes 4b f2365 at 2.07 a3 resolution

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0