Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	Y	T	K	I	I	G	T	G	S	Y	L	P	E	Q	V	R	T	N	A	D	L	E	K	M	V	D	T	S	D	E	W	I	V	T	R	T	G	I	R	E	R	H	I	A	A	P	N	E	T	V	S	T	M	G	F	E	A	A	T
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	A	I	E	M	A	G	I	E	K	D	Q	I	G	L	I	V	V	A	T	T	S	A	T	H	A	F	P	S	A	A	C	Q	I	Q	S	M	L	G	I	K	G	C	P	A	F	D	V	A	A	A	C	A	G	F	T	Y	A	L	S
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	A	D	Q	Y	V	K	S	G	A	V	K	Y	A	L	V	V	G	S	D	V	L	A	R	T	C	D	P	T	D	R	G	T	I	I	I	F	G	D	G	A	G	A	A	V	L	A	A	S	E	E	P	G	I	I	S	T	H	L	H
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	D	G	S	Y	G	E	L	L	T	L	P	N	A	D	R	V	N	P	E	N	S	I	H	L	T	M	A	G	N	E	V	F	K	V	A	V	T	E	L	A	H	I	V	D	E	T	L	A	A	N	N	L	D	R	S	Q	L	D	W
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		L	V	P	H	Q	A	N	L	R	I	I	S	A	T	A	K	K	L	G	M	S	M	D	N	V	V	V	T	L	D	R	H	G	N	T	S	A	A	S	V	P	C	A	L	D	E	A	V	R	D	G	R	I	K	P	G	Q	L	V	L
Secondary structure
SS confidence
Disorder																																																					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.
Sequence		L	E	A	F	G	G	G	F	T	W	G	S	A	L	V	R	F
Secondary structure
SS confidence
Disorder																	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2gyo chain B Region: 1 - 317 Aligned: 317 Modelled: 317 Confidence: 100.0% Identity: 100% PDB header:transferase Chain: B: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 3; PDBTitle: methanethiol-cys 112 inhibition complex of e. coli ketoacyl synthase2 iii (fabh) and coenzyme a Phyre2 PDB 3il3 chain A Region: 1 - 317 Aligned: 315 Modelled: 317 Confidence: 100.0% Identity: 66% PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 3; PDBTitle: structure of haemophilus influenzae fabh Phyre2 PDB 1mzj chain B Region: 2 - 317 Aligned: 316 Modelled: 316 Confidence: 100.0% Identity: 38% PDB header:transferase Chain: B: PDB Molecule:beta-ketoacylsynthase iii; PDBTitle: crystal structure of the priming beta-ketosynthase from the2 r1128 polyketide biosynthetic pathway Phyre2 PDB 2qnx chain A Region: 2 - 317 Aligned: 316 Modelled: 316 Confidence: 100.0% Identity: 36% PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 3; PDBTitle: crystal structure of the complex between the mycobacterium beta-2 ketoacyl-acyl carrier protein synthase iii (fabh) and 11-3 [(decyloxycarbonyl)dithio]-undecanoic acid Phyre2 PDB 1zow chain B Region: 1 - 317 Aligned: 310 Modelled: 317 Confidence: 100.0% Identity: 42% PDB header:transferase Chain: B: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase iii; PDBTitle: crystal structure of s. aureus fabh, beta-ketoacyl carrier protein2 synthase iii Phyre2 PDB 2ebd chain B Region: 3 - 317 Aligned: 306 Modelled: 315 Confidence: 100.0% Identity: 48% PDB header:transferase Chain: B: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 3; PDBTitle: crystal structure of 3-oxoacyl-[acyl-carrier-protein] synthase iii2 from aquifex aeolicus vf5 Phyre2 PDB 3h76 chain A Region: 2 - 317 Aligned: 314 Modelled: 316 Confidence: 100.0% Identity: 40% PDB header:transferase Chain: A: PDB Molecule:pqs biosynthetic enzyme; PDBTitle: crystal structure of pqsd, a key enzyme in pseudomonas2 aeruginosa quinolone signal biosynthesis pathway Phyre2 PDB 3gwa chain A Region: 3 - 317 Aligned: 315 Modelled: 315 Confidence: 100.0% Identity: 32% PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-(acyl-carrier-protein) synthase iii; PDBTitle: 1.6 angstrom crystal structure of 3-oxoacyl-(acyl-carrier-protein)2 synthase iii Phyre2 PDB 1ub7 chain A Region: 3 - 317 Aligned: 313 Modelled: 315 Confidence: 100.0% Identity: 41% PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier protein] synthase; PDBTitle: the crystal analysis of beta-keroacyl-[acyl carrier protein] synthase2 iii (fabh)from thermus thermophilus. Phyre2 PDB 3il5 chain D Region: 2 - 316 Aligned: 309 Modelled: 315 Confidence: 100.0% Identity: 40% PDB header:transferase Chain: D: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 3; PDBTitle: structure of e. faecalis fabh in complex with 2-({4-bromo-3-2 [(diethylamino)sulfonyl]benzoyl}amino)benzoic acid Phyre2 PDB 2x3e chain A Region: 2 - 317 Aligned: 313 Modelled: 316 Confidence: 100.0% Identity: 40% PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 3; PDBTitle: crystal structure of 3-oxoacyl-(acyl carrier protein)2 synthase iii, fabh from pseudomonas aeruginosa pao1 Phyre2 PDB 3fk5 chain A Region: 2 - 317 Aligned: 316 Modelled: 316 Confidence: 100.0% Identity: 23% PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-synthase iii; PDBTitle: crystal structure of 3-oxoacyl-(acyl carrier protein)2 synthase iii, fabh (xoo4209) from xanthomonas oryzae pv.3 oryzae kacc10331 Phyre2 PDB 1u0m chain A Region: 3 - 317 Aligned: 307 Modelled: 315 Confidence: 100.0% Identity: 22% PDB header:biosynthetic protein Chain: A: PDB Molecule:putative polyketide synthase; PDBTitle: crystal structure of 1,3,6,8-tetrahydroxynaphthalene synthase (thns)2 from streptomyces coelicolor a3(2): a bacterial type iii polyketide3 synthase (pks) provides insights into enzymatic control of reactive4 polyketide intermediates Phyre2 PDB 1ee0 chain A Region: 3 - 317 Aligned: 314 Modelled: 315 Confidence: 100.0% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:2-pyrone synthase; PDBTitle: 2-pyrone synthase complexed with acetoacetyl-coa Phyre2 PDB 2f9a chain A Region: 2 - 316 Aligned: 305 Modelled: 315 Confidence: 100.0% Identity: 20% PDB header:transferase Chain: A: PDB Molecule:3-hydroxy-3-methylglutaryl coenzyme a synthase 1; PDBTitle: hmg-coa synthase from brassica juncea in complex with f-244 Phyre2 PDB 1cml chain A Region: 3 - 317 Aligned: 314 Modelled: 310 Confidence: 100.0% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:protein (chalcone synthase); PDBTitle: chalcone synthase from alfalfa complexed with malonyl-coa Phyre2 PDB 3ale chain B Region: 1 - 317 Aligned: 311 Modelled: 310 Confidence: 100.0% Identity: 21% PDB header:transferase Chain: B: PDB Molecule:os07g0271500 protein; PDBTitle: a type iii polyketide synthase that produces diarylheptanoid Phyre2 PDB 1x9e chain B Region: 1 - 316 Aligned: 304 Modelled: 316 Confidence: 100.0% Identity: 19% PDB header:lyase Chain: B: PDB Molecule:hmg-coa synthase; PDBTitle: crystal structure of hmg-coa synthase from enterococcus2 faecalis Phyre2 PDB 2h84 chain A Region: 2 - 317 Aligned: 313 Modelled: 316 Confidence: 100.0% Identity: 22% PDB header:biosynthetic protein, transferase Chain: A: PDB Molecule:steely1; PDBTitle: crystal structure of the c-terminal type iii polyketide synthase (pks2 iii) domain of 'steely1' (a type i/iii pks hybrid from dictyostelium) Phyre2 PDB 3led chain A Region: 2 - 316 Aligned: 312 Modelled: 315 Confidence: 100.0% Identity: 28% PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-acyl carrier protein synthase iii; PDBTitle: crystal structure of 3-oxoacyl-(acyl carrier protein) synthase iii2 from rhodopseudomonas palustris cga009 Phyre2 1 c2gyoB_ 2 c3il3A_ 3 c1mzjB_ 4 c2qnxA_ 5 c1zowB_ 6 c2ebdB_ 7 c3h76A_ 8 c3gwaA_ 9 c1ub7A_ 10 c3il5D_ 11 c2x3eA_ 12 c3fk5A_ 13 c1u0mA_ 14 c1ee0A_ 15 c2f9aA_ 16 c1cmlA_ 17 c3aleB_ 18 c1x9eB_ 19 c2h84A_ 20 c3ledA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2gyoB_ 100.0 100 PDB header:transferase Chain: B: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 3; PDBTitle: methanethiol-cys 112 inhibition complex of e. coli ketoacyl synthase2 iii (fabh) and coenzyme a 2 c3il3A_ 100.0 66 PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 3; PDBTitle: structure of haemophilus influenzae fabh 3 c1mzjB_ 100.0 38 PDB header:transferase Chain: B: PDB Molecule:beta-ketoacylsynthase iii; PDBTitle: crystal structure of the priming beta-ketosynthase from the2 r1128 polyketide biosynthetic pathway 4 c2qnxA_ 100.0 36 PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 3; PDBTitle: crystal structure of the complex between the mycobacterium beta-2 ketoacyl-acyl carrier protein synthase iii (fabh) and 11-3 [(decyloxycarbonyl)dithio]-undecanoic acid 5 c1zowB_ 100.0 42 PDB header:transferase Chain: B: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase iii; PDBTitle: crystal structure of s. aureus fabh, beta-ketoacyl carrier protein2 synthase iii 6 c2ebdB_ 100.0 48 PDB header:transferase Chain: B: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 3; PDBTitle: crystal structure of 3-oxoacyl-[acyl-carrier-protein] synthase iii2 from aquifex aeolicus vf5 7 c3h76A_ 100.0 40 PDB header:transferase Chain: A: PDB Molecule:pqs biosynthetic enzyme; PDBTitle: crystal structure of pqsd, a key enzyme in pseudomonas2 aeruginosa quinolone signal biosynthesis pathway 8 c3gwaA_ 100.0 32 PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-(acyl-carrier-protein) synthase iii; PDBTitle: 1.6 angstrom crystal structure of 3-oxoacyl-(acyl-carrier-protein)2 synthase iii 9 c1ub7A_ 100.0 41 PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier protein] synthase; PDBTitle: the crystal analysis of beta-keroacyl-[acyl carrier protein] synthase2 iii (fabh)from thermus thermophilus. 10 c3il5D_ 100.0 40 PDB header:transferase Chain: D: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 3; PDBTitle: structure of e. faecalis fabh in complex with 2-({4-bromo-3-2 [(diethylamino)sulfonyl]benzoyl}amino)benzoic acid 11 c2x3eA_ 100.0 40 PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 3; PDBTitle: crystal structure of 3-oxoacyl-(acyl carrier protein)2 synthase iii, fabh from pseudomonas aeruginosa pao1 12 c3fk5A_ 100.0 23 PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-synthase iii; PDBTitle: crystal structure of 3-oxoacyl-(acyl carrier protein)2 synthase iii, fabh (xoo4209) from xanthomonas oryzae pv.3 oryzae kacc10331 13 c1u0mA_ 100.0 22 PDB header:biosynthetic protein Chain: A: PDB Molecule:putative polyketide synthase; PDBTitle: crystal structure of 1,3,6,8-tetrahydroxynaphthalene synthase (thns)2 from streptomyces coelicolor a3(2): a bacterial type iii polyketide3 synthase (pks) provides insights into enzymatic control of reactive4 polyketide intermediates 14 c1ee0A_ 100.0 21 PDB header:transferase Chain: A: PDB Molecule:2-pyrone synthase; PDBTitle: 2-pyrone synthase complexed with acetoacetyl-coa 15 c2f9aA_ 100.0 20 PDB header:transferase Chain: A: PDB Molecule:3-hydroxy-3-methylglutaryl coenzyme a synthase 1; PDBTitle: hmg-coa synthase from brassica juncea in complex with f-244 16 c1cmlA_ 100.0 21 PDB header:transferase Chain: A: PDB Molecule:protein (chalcone synthase); PDBTitle: chalcone synthase from alfalfa complexed with malonyl-coa 17 c3aleB_ 100.0 21 PDB header:transferase Chain: B: PDB Molecule:os07g0271500 protein; PDBTitle: a type iii polyketide synthase that produces diarylheptanoid 18 c1x9eB_ 100.0 19 PDB header:lyase Chain: B: PDB Molecule:hmg-coa synthase; PDBTitle: crystal structure of hmg-coa synthase from enterococcus2 faecalis 19 c2h84A_ 100.0 22 PDB header:biosynthetic protein, transferase Chain: A: PDB Molecule:steely1; PDBTitle: crystal structure of the c-terminal type iii polyketide synthase (pks2 iii) domain of 'steely1' (a type i/iii pks hybrid from dictyostelium) 20 c3ledA_ 100.0 28 PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-acyl carrier protein synthase iii; PDBTitle: crystal structure of 3-oxoacyl-(acyl carrier protein) synthase iii2 from rhodopseudomonas palustris cga009 21 c1xetD_ not modelled 100.0 20 PDB header:transferase Chain: D: PDB Molecule:dihydropinosylvin synthase; PDBTitle: crystal structure of stilbene synthase from pinus2 sylvestris, complexed with methylmalonyl coa 22 c3s3lB_ not modelled 100.0 20 PDB header:transferase Chain: B: PDB Molecule:cerj; PDBTitle: crystal structure of cerj from streptomyces tendae 23 c3oitB_ not modelled 100.0 22 PDB header:transferase Chain: B: PDB Molecule:os07g0271500 protein; PDBTitle: crystal structure of curcuminoid synthase cus from oryza sativa 24 c2v4wB_ not modelled 100.0 19 PDB header:transferase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa synthase, PDBTitle: crystal structure of human mitochondrial 3-hydroxy-3-2 methylglutaryl-coenzyme a synthase 2 (hmgcs2) 25 d1teda_ not modelled 100.0 23 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 26 c3a5qA_ not modelled 100.0 20 PDB header:transferase Chain: A: PDB Molecule:benzalacetone synthase; PDBTitle: benzalacetone synthase from rheum palmatum 27 c1txtB_ not modelled 100.0 20 PDB header:lyase Chain: B: PDB Molecule:3-hydroxy-3-methylglutaryl-coa synthase; PDBTitle: staphylococcus aureus 3-hydroxy-3-methylglutaryl-coa2 synthase 28 c2p0uB_ not modelled 100.0 23 PDB header:transferase Chain: B: PDB Molecule:stilbenecarboxylate synthase 2; PDBTitle: crystal structure of marchantia polymorpha stilbenecarboxylate2 synthase 2 (stcs2) 29 c2p8uB_ not modelled 100.0 17 PDB header:transferase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa synthase, cytoplasmic; PDBTitle: crystal structure of human 3-hydroxy-3-methylglutaryl coa synthase i 30 c3ov3A_ not modelled 100.0 22 PDB header:transferase Chain: A: PDB Molecule:curcumin synthase; PDBTitle: g211f mutant of curcumin synthase 1 from curcuma longa 31 c3e1hA_ not modelled 100.0 20 PDB header:transferase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of a type iii polyketide synthase2 pksiiinc from neurospora crassa 32 c3euoB_ not modelled 100.0 21 PDB header:transferase Chain: B: PDB Molecule:type iii pentaketide synthase; PDBTitle: crystal structure of a fungal type iii polyketide synthase,2 oras 33 c2d3mA_ not modelled 100.0 20 PDB header:transferase Chain: A: PDB Molecule:pentaketide chromone synthase; PDBTitle: pentaketide chromone synthase complexed with coenzyme a 34 c3lehA_ not modelled 100.0 19 PDB header:transferase Chain: A: PDB Molecule:putative hydroxymethylglutaryl-coa synthase; PDBTitle: the crystal structure of smu.943c from streptococcus mutans ua159 35 c3tsyA_ not modelled 100.0 21 PDB header:ligase, transferase Chain: A: PDB Molecule:fusion protein 4-coumarate--coa ligase 1, resveratrol PDBTitle: 4-coumaroyl-coa ligase::stilbene synthase fusion protein 36 d1hnja1 not modelled 100.0 100 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 37 d1mzja1 not modelled 100.0 42 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 38 d1u6ea1 not modelled 100.0 40 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 39 d1ub7a1 not modelled 100.0 40 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 40 d1xpma1 not modelled 100.0 27 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 41 d1bi5a1 not modelled 100.0 25 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 42 d1ee0a1 not modelled 100.0 27 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 43 d1u0ma1 not modelled 100.0 24 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 44 d1u0ua1 not modelled 100.0 23 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 45 c2vu2D_ not modelled 100.0 20 PDB header:transferase Chain: D: PDB Molecule:acetyl-coa acetyltransferase; PDBTitle: biosynthetic thiolase from z. ramigera. complex with s-2 pantetheine-11-pivalate. 46 c2iikA_ not modelled 100.0 15 PDB header:transferase Chain: A: PDB Molecule:3-ketoacyl-coa thiolase, peroxisomal; PDBTitle: crystal structure of human peroxisomal acetyl-coa acyl transferase 12 (acaa1) 47 d1u0va1 not modelled 100.0 26 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 48 d1hnja2 not modelled 100.0 100 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 49 c3ss6B_ not modelled 100.0 18 PDB header:transferase Chain: B: PDB Molecule:acetyl-coa acetyltransferase; PDBTitle: crystal structure of the bacillus anthracis acetyl-coa2 acetyltransferase 50 d1ub7a2 not modelled 99.9 42 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 51 c2c7yB_ not modelled 99.9 20 PDB header:transferase Chain: B: PDB Molecule:3-ketoacyl-coa thiolase 2; PDBTitle: plant enzyme 52 c1wl5A_ not modelled 99.9 17 PDB header:transferase Chain: A: PDB Molecule:acetyl-coenzyme a acetyltransferase 2; PDBTitle: human cytosolic acetoacetyl-coa thiolase 53 c2ibyD_ not modelled 99.9 19 PDB header:transferase Chain: D: PDB Molecule:acetyl-coa acetyltransferase; PDBTitle: crystallographic and kinetic studies of human mitochondrial2 acetoacetyl-coa thiolase (t2): the importance of potassium and3 chloride for its structure and function 54 c2vz8B_ not modelled 99.9 20 PDB header:transferase Chain: B: PDB Molecule:fatty acid synthase; PDBTitle: crystal structure of mammalian fatty acid synthase 55 c2qo3A_ not modelled 99.9 22 PDB header:transferase Chain: A: PDB Molecule:eryaii erythromycin polyketide synthase modules 3 and 4; PDBTitle: crystal structure of [ks3][at3] didomain from module 3 of 6-2 deoxyerthronolide b synthase 56 c1ulqD_ not modelled 99.9 20 PDB header:transferase Chain: D: PDB Molecule:putative acetyl-coa acetyltransferase; PDBTitle: crystal structure of tt0182 from thermus thermophilus hb8 57 c3goaA_ not modelled 99.9 15 PDB header:transferase Chain: A: PDB Molecule:3-ketoacyl-coa thiolase; PDBTitle: crystal structure of the salmonella typhimurium fada 3-2 ketoacyl-coa thiolase 58 c2wuaA_ not modelled 99.9 18 PDB header:transferase Chain: A: PDB Molecule:acetoacetyl coa thiolase; PDBTitle: structure of the peroxisomal 3-ketoacyl-coa thiolase from2 sunflower 59 d1mzja2 not modelled 99.9 33 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 60 c1afwB_ not modelled 99.9 18 PDB header:thiolase Chain: B: PDB Molecule:3-ketoacetyl-coa thiolase; PDBTitle: the 1.8 angstrom crystal structure of the dimeric2 peroxisomal thiolase of saccharomyces cerevisiae 61 d1u6ea2 not modelled 99.9 31 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 62 c2hg4A_ not modelled 99.9 21 PDB header:transferase Chain: A: PDB Molecule:6-deoxyerythronolide b synthase; PDBTitle: structure of the ketosynthase-acyltransferase didomain of module 52 from debs. 63 c3hhdC_ not modelled 99.9 18 PDB header:transferase, hydrolase Chain: C: PDB Molecule:fatty acid synthase; PDBTitle: structure of the human fatty acid synthase ks-mat didomain2 as a framework for inhibitor design. 64 c1tqyC_ not modelled 99.9 17 PDB header:transferase Chain: C: PDB Molecule:beta-ketoacyl synthase/acyl transferase; PDBTitle: the actinorhodin ketosynthase/chain length factor 65 c1j3nB_ not modelled 99.9 17 PDB header:transferase Chain: B: PDB Molecule:3-oxoacyl-(acyl-carrier protein) synthase ii; PDBTitle: crystal structure of 3-oxoacyl-(acyl-carrier protein)2 synthase ii from thermus thermophilus hb8 66 c3e60A_ not modelled 99.9 18 PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein ] synthase ii; PDBTitle: crystal structure of 3-oxoacyl-(acyl carrier protein)2 synthase ii from bartonella henselae 67 c2gqdB_ not modelled 99.9 16 PDB header:transferase Chain: B: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 2; PDBTitle: the crystal structure of b-ketoacyl-acp synthase ii (fabf)2 from staphylococcus aureus 68 c1oxhD_ not modelled 99.9 17 PDB header:transferase Chain: D: PDB Molecule:beta ketoacyl-acyl carrier protein synthase; PDBTitle: the crystal structure of beta-ketoacyl-[acyl carrier2 protein] synthase ii from streptococcus pneumoniae,3 triclinic form 69 c2ix4B_ not modelled 99.9 14 PDB header:transferase Chain: B: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase; PDBTitle: arabidopsis thaliana mitochondrial beta-ketoacyl acp2 synthase hexanoic acid complex 70 d1u0ma2 not modelled 99.9 20 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 71 c3o04A_ not modelled 99.9 16 PDB header:transferase Chain: A: PDB Molecule:beta-keto-acyl carrier protein synthase ii; PDBTitle: crystal structure of the beta-keto-acyl carrier protein synthase ii2 (lmo2201) from listeria monocytogenes 72 c2d3tC_ not modelled 99.9 19 PDB header:lyase, oxidoreductase/transferase Chain: C: PDB Molecule:3-ketoacyl-coa thiolase; PDBTitle: fatty acid beta-oxidation multienzyme complex from2 pseudomonas fragi, form v 73 c1e5mA_ not modelled 99.9 15 PDB header:condensing enzyme Chain: A: PDB Molecule:beta ketoacyl acyl carrier protein synthase ii; PDBTitle: beta ketoacyl acyl carrier protein synthase ii (kasii) from2 synechocystis sp. 74 c2gfvA_ not modelled 99.9 16 PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 2; PDBTitle: structure of e. coli fabf (kasii) c163q mutant 75 c2iwyB_ not modelled 99.9 14 PDB header:transferase Chain: B: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase; PDBTitle: human mitochondrial beta-ketoacyl acp synthase 76 d1u0ua2 not modelled 99.9 15 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 77 c2gp6B_ not modelled 99.9 18 PDB header:transferase Chain: B: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 2; PDBTitle: x-ray crystal structure of mycobacterium tuberculosis beta-2 ketoacyl acyl carrier protein synthase ii (mtkasb) 78 c3lrfA_ not modelled 99.9 18 PDB header:transferase Chain: A: PDB Molecule:beta-ketoacyl synthase; PDBTitle: crystal structure of beta-ketoacyl synthase from brucella2 melitensis 79 c1tqyD_ not modelled 99.9 17 PDB header:transferase Chain: D: PDB Molecule:actinorhodin polyketide putative beta-ketoacyl synthase 2; PDBTitle: the actinorhodin ketosynthase/chain length factor 80 c2wggA_ not modelled 99.9 16 PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 1; PDBTitle: crystal structure of mycobacterium tuberculosis c171q kasa2 variant with bound tlm 81 d1bi5a2 not modelled 99.9 18 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 82 c2buiC_ not modelled 99.9 16 PDB header:synthase Chain: C: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase i; PDBTitle: e.coli beta-ketoacyl (acyl carrier protein) synthase i in2 complex with octanoic acid, 120k 83 d1ee0a2 not modelled 99.9 17 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 84 c3svkB_ not modelled 99.8 15 PDB header:transferase Chain: B: PDB Molecule:acetyl-coa acetyltransferase; PDBTitle: crystal structure of acetyl-coa acetyltransferase from mycobacterium2 avium 85 c2uv9B_ not modelled 99.8 19 PDB header:transferase Chain: B: PDB Molecule:fatty acid synthase alpha subunits; PDBTitle: crystal structure of fatty acid synthase from thermomyces2 lanuginosus at 3.1 angstrom resolution. this file contains3 the alpha subunits of the fatty acid synthase. the entire4 crystal structure consists of one heterododecameric fatty5 acid synthase and is described in remark 400 86 c2uv8C_ not modelled 99.8 18 PDB header:transferase Chain: C: PDB Molecule:fatty acid synthase subunit alpha (fas2); PDBTitle: crystal structure of yeast fatty acid synthase with stalled2 acyl carrier protein at 3.1 angstrom resolution 87 d1xpma2 not modelled 99.8 13 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 88 c2vkzC_ not modelled 99.7 18 PDB header:transferase Chain: C: PDB Molecule:fatty acid synthase subunit alpha; PDBTitle: structure of the cerulenin-inhibited fungal fatty acid2 synthase type i multienzyme complex 89 d1m3ka1 not modelled 99.7 14 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 90 c3lmaC_ not modelled 99.6 16 PDB header:membrane protein Chain: C: PDB Molecule:stage v sporulation protein ad (spovad); PDBTitle: crystal structure of the stage v sporulation protein ad2 (spovad) from bacillus licheniformis. northeast structural3 genomics consortium target bir6. 91 d1ulqa1 not modelled 99.6 16 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 92 d1afwa1 not modelled 99.5 12 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 93 d1wdkc1 not modelled 99.4 17 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 94 d2vbaa1 not modelled 99.4 15 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 95 d2ix4a1 not modelled 99.3 14 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 96 d1ox0a1 not modelled 99.3 18 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 97 d1j3na1 not modelled 99.2 20 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 98 d1e5ma1 not modelled 99.2 20 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 99 d2gfva1 not modelled 99.1 17 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 100 d1tqya1 not modelled 98.9 18 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 101 d1tqyb2 not modelled 98.9 16 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 102 d1tqyb1 not modelled 98.9 23 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 103 d1tqya2 not modelled 98.8 16 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 104 d1afwa2 not modelled 98.6 16 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 105 d1m3ka2 not modelled 98.5 18 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 106 d1ox0a2 not modelled 98.4 14 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 107 d1ulqa2 not modelled 98.3 18 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 108 d1wdkc2 not modelled 98.3 12 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 109 d1e5ma2 not modelled 98.2 15 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 110 d1j3na2 not modelled 98.2 12 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 111 d2gfva2 not modelled 98.2 19 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 112 d2ix4a2 not modelled 97.8 16 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 113 d2vbaa2 not modelled 97.0 15 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 114 d1xhoa_ not modelled 77.2 13 Fold:Bacillus chorismate mutase-like Superfamily:YjgF-like Family:Chorismate mutase 115 c1xhoB_ not modelled 77.2 13 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:chorismate mutase; PDBTitle: chorismate mutase from clostridium thermocellum cth-682 116 c2a6aB_ not modelled 74.6 5 PDB header:hydrolase Chain: B: PDB Molecule:hypothetical protein tm0874; PDBTitle: crystal structure of glycoprotein endopeptidase (tm0874) from2 thermotoga maritima at 2.50 a resolution 117 d2a6aa1 not modelled 73.1 5 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:YeaZ-like 118 d1okja1 not modelled 72.5 11 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:YeaZ-like 119 d1dbfa_ not modelled 71.3 12 Fold:Bacillus chorismate mutase-like Superfamily:YjgF-like Family:Chorismate mutase 120 c2r2dC_ not modelled 70.8 19 PDB header:hydrolase Chain: C: PDB Molecule:zn-dependent hydrolases; PDBTitle: structure of a quorum-quenching lactonase (aiib) from agrobacterium2 tumefaciens

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0