Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	F	E	L	D	T	T	D	G	R	A	R	R	G	R	L	V	F	D	R	G	V	V	E	T	P	C	F	M	P	V	G	T	Y	G	T	V	K	G	M	T	P	E	E	V	E	A	T	G	A	Q	I	I	L	G	N	T	F	H
Secondary structure
SS confidence
Disorder		?							?												?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	W	L	R	P	G	Q	E	I	M	K	L	H	G	D	L	H	D	F	M	Q	W	K	G	P	I	L	T	D	S	G	G	F	Q	V	F	S	L	G	D	I	R	K	I	T	E	Q	G	V	H	F	R	N	P	I	N	G	D	P	I
Secondary structure
SS confidence
Disorder					?	?							?																				?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		F	L	D	P	E	K	S	M	E	I	Q	Y	D	L	G	S	D	I	V	M	I	F	D	E	C	T	P	Y	P	A	D	W	D	Y	A	K	R	S	M	E	M	S	L	R	W	A	K	R	S	R	E	R	F	D	S	L	G	N	K	N
Secondary structure
SS confidence
Disorder																																?																								?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	L	F	G	I	I	Q	G	S	V	Y	E	D	L	R	D	I	S	V	K	G	L	V	D	I	G	F	D	G	Y	A	V	G	G	L	A	V	G	E	P	K	A	D	M	H	R	I	L	E	H	V	C	P	Q	I	P	A	D	K	P
Secondary structure
SS confidence
Disorder																										?												?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		R	Y	L	M	G	V	G	K	P	E	D	L	V	E	G	V	R	R	G	I	D	M	F	D	C	V	M	P	T	R	N	A	R	N	G	H	L	F	V	T	D	G	V	V	K	I	R	N	A	K	Y	K	S	D	T	G	P	L	D	P
Secondary structure
SS confidence
Disorder																																																				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		E	C	D	C	Y	T	C	R	N	Y	S	R	A	Y	L	H	H	L	D	R	C	N	E	I	L	G	A	R	L	N	T	I	H	N	L	R	Y	Y	Q	R	L	M	A	G	L	R	K	A	I	E	E	G	K	L	E	S	F	V	T	D
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.
Sequence		F	Y	Q	R	Q	G	R	E	V	P	P	L	N	V	D
Secondary structure
SS confidence
Disorder										?		?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2ash chain B Region: 2 - 366 Aligned: 360 Modelled: 365 Confidence: 100.0% Identity: 49% PDB header:transferase Chain: B: PDB Molecule:queuine trna-ribosyltransferase; PDBTitle: crystal structure of queuine trna-ribosyltransferase (ec 2.4.2.29)2 (trna-guanine (tm1561) from thermotoga maritima at 1.90 a resolution Phyre2 PDB 1r5y chain A Region: 1 - 366 Aligned: 355 Modelled: 366 Confidence: 100.0% Identity: 58% Fold: TIM beta/alpha-barrel Superfamily: tRNA-guanine transglycosylase Family: tRNA-guanine transglycosylase Phyre2 PDB 1iq8 chain B Region: 1 - 372 Aligned: 332 Modelled: 353 Confidence: 100.0% Identity: 28% PDB header:transferase Chain: B: PDB Molecule:archaeosine trna-guanine transglycosylase; PDBTitle: crystal structure of archaeosine trna-guanine2 transglycosylase from pyrococcus horikoshii Phyre2 PDB 1iq8 chain A domain 1 Region: 1 - 372 Aligned: 332 Modelled: 345 Confidence: 100.0% Identity: 29% Fold: TIM beta/alpha-barrel Superfamily: tRNA-guanine transglycosylase Family: tRNA-guanine transglycosylase Phyre2 PDB 3bg3 chain B Region: 124 - 295 Aligned: 162 Modelled: 172 Confidence: 95.9% Identity: 14% PDB header:ligase Chain: B: PDB Molecule:pyruvate carboxylase, mitochondrial; PDBTitle: crystal structure of human pyruvate carboxylase (missing2 the biotin carboxylase domain at the n-terminus) Phyre2 PDB 1rr2 chain A Region: 125 - 295 Aligned: 158 Modelled: 171 Confidence: 95.2% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:transcarboxylase 5s subunit; PDBTitle: propionibacterium shermanii transcarboxylase 5s subunit bound to 2-2 ketobutyric acid Phyre2 PDB 3ewb chain X Region: 157 - 277 Aligned: 121 Modelled: 120 Confidence: 94.4% Identity: 10% PDB header:transferase Chain: X: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of n-terminal domain of putative 2-2 isopropylmalate synthase from listeria monocytogenes Phyre2 PDB 1ydn chain A Region: 125 - 266 Aligned: 140 Modelled: 141 Confidence: 93.3% Identity: 12% PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of the hmg-coa lyase from brucella melitensis,2 northeast structural genomics target lr35. Phyre2 PDB 1ydo chain C Region: 125 - 267 Aligned: 141 Modelled: 143 Confidence: 92.3% Identity: 13% PDB header:lyase Chain: C: PDB Molecule:hmg-coa lyase; PDBTitle: crystal structure of the bacillis subtilis hmg-coa lyase, northeast2 structural genomics target sr181. Phyre2 PDB 3flu chain D Region: 187 - 307 Aligned: 112 Modelled: 121 Confidence: 91.8% Identity: 12% PDB header:lyase Chain: D: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from the pathogen2 neisseria meningitidis Phyre2 PDB 3eeg chain B Region: 166 - 277 Aligned: 112 Modelled: 112 Confidence: 91.7% Identity: 10% PDB header:transferase Chain: B: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of a 2-isopropylmalate synthase from2 cytophaga hutchinsonii Phyre2 PDB 2ftp chain A Region: 128 - 266 Aligned: 137 Modelled: 139 Confidence: 91.4% Identity: 15% PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of hydroxymethylglutaryl-coa lyase from pseudomonas2 aeruginosa Phyre2 PDB 1qap chain A domain 1 Region: 199 - 273 Aligned: 67 Modelled: 75 Confidence: 90.7% Identity: 15% Fold: TIM beta/alpha-barrel Superfamily: Nicotinate/Quinolinate PRTase C-terminal domain-like Family: NadC C-terminal domain-like Phyre2 PDB 1sr9 chain A domain 2 Region: 148 - 295 Aligned: 148 Modelled: 148 Confidence: 90.5% Identity: 7% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: HMGL-like Phyre2 PDB 3nav chain B Region: 123 - 263 Aligned: 139 Modelled: 141 Confidence: 90.4% Identity: 17% PDB header:lyase Chain: B: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: crystal structure of an alpha subunit of tryptophan synthase from2 vibrio cholerae o1 biovar el tor str. n16961 Phyre2 PDB 1nvm chain G Region: 125 - 277 Aligned: 138 Modelled: 138 Confidence: 90.0% Identity: 14% PDB header:lyase/oxidoreductase Chain: G: PDB Molecule:4-hydroxy-2-oxovalerate aldolase; PDBTitle: crystal structure of a bifunctional aldolase-dehydrogenase :2 sequestering a reactive and volatile intermediate Phyre2 PDB 3bg5 chain C Region: 125 - 295 Aligned: 152 Modelled: 171 Confidence: 89.3% Identity: 17% PDB header:ligase Chain: C: PDB Molecule:pyruvate carboxylase; PDBTitle: crystal structure of staphylococcus aureus pyruvate2 carboxylase Phyre2 PDB 1nvm chain A domain 2 Region: 125 - 277 Aligned: 138 Modelled: 138 Confidence: 88.5% Identity: 14% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: HMGL-like Phyre2 PDB 2cw6 chain B Region: 125 - 266 Aligned: 140 Modelled: 142 Confidence: 86.9% Identity: 12% PDB header:lyase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria Phyre2 PDB 3pue chain A Region: 188 - 263 Aligned: 75 Modelled: 76 Confidence: 86.7% Identity: 16% PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of the complex of dhydrodipicolinate synthase from2 acinetobacter baumannii with lysine at 2.6a resolution Phyre2 1 c2ashB_ 2 d1r5ya_ 3 c1iq8B_ 4 d1iq8a1 5 c3bg3B_ 6 c1rr2A_ 7 c3ewbX_ 8 c1ydnA_ 9 c1ydoC_ 10 c3fluD_ 11 c3eegB_ 12 c2ftpA_ 13 d1qapa1 14 d1sr9a2 15 c3navB_ 16 c1nvmG_ 17 c3bg5C_ 18 d1nvma2 19 c2cw6B_ 20 c3pueA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2ashB_ 100.0 49 PDB header:transferase Chain: B: PDB Molecule:queuine trna-ribosyltransferase; PDBTitle: crystal structure of queuine trna-ribosyltransferase (ec 2.4.2.29)2 (trna-guanine (tm1561) from thermotoga maritima at 1.90 a resolution 2 d1r5ya_ 100.0 58 Fold:TIM beta/alpha-barrel Superfamily:tRNA-guanine transglycosylase Family:tRNA-guanine transglycosylase 3 c1iq8B_ 100.0 28 PDB header:transferase Chain: B: PDB Molecule:archaeosine trna-guanine transglycosylase; PDBTitle: crystal structure of archaeosine trna-guanine2 transglycosylase from pyrococcus horikoshii 4 d1iq8a1 100.0 29 Fold:TIM beta/alpha-barrel Superfamily:tRNA-guanine transglycosylase Family:tRNA-guanine transglycosylase 5 c3bg3B_ 95.9 14 PDB header:ligase Chain: B: PDB Molecule:pyruvate carboxylase, mitochondrial; PDBTitle: crystal structure of human pyruvate carboxylase (missing2 the biotin carboxylase domain at the n-terminus) 6 c1rr2A_ 95.2 16 PDB header:transferase Chain: A: PDB Molecule:transcarboxylase 5s subunit; PDBTitle: propionibacterium shermanii transcarboxylase 5s subunit bound to 2-2 ketobutyric acid 7 c3ewbX_ 94.4 10 PDB header:transferase Chain: X: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of n-terminal domain of putative 2-2 isopropylmalate synthase from listeria monocytogenes 8 c1ydnA_ 93.3 12 PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of the hmg-coa lyase from brucella melitensis,2 northeast structural genomics target lr35. 9 c1ydoC_ 92.3 13 PDB header:lyase Chain: C: PDB Molecule:hmg-coa lyase; PDBTitle: crystal structure of the bacillis subtilis hmg-coa lyase, northeast2 structural genomics target sr181. 10 c3fluD_ 91.8 12 PDB header:lyase Chain: D: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from the pathogen2 neisseria meningitidis 11 c3eegB_ 91.7 10 PDB header:transferase Chain: B: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of a 2-isopropylmalate synthase from2 cytophaga hutchinsonii 12 c2ftpA_ 91.4 15 PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of hydroxymethylglutaryl-coa lyase from pseudomonas2 aeruginosa 13 d1qapa1 90.7 15 Fold:TIM beta/alpha-barrel Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like Family:NadC C-terminal domain-like 14 d1sr9a2 90.5 7 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:HMGL-like 15 c3navB_ 90.4 17 PDB header:lyase Chain: B: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: crystal structure of an alpha subunit of tryptophan synthase from2 vibrio cholerae o1 biovar el tor str. n16961 16 c1nvmG_ 90.0 14 PDB header:lyase/oxidoreductase Chain: G: PDB Molecule:4-hydroxy-2-oxovalerate aldolase; PDBTitle: crystal structure of a bifunctional aldolase-dehydrogenase :2 sequestering a reactive and volatile intermediate 17 c3bg5C_ 89.3 17 PDB header:ligase Chain: C: PDB Molecule:pyruvate carboxylase; PDBTitle: crystal structure of staphylococcus aureus pyruvate2 carboxylase 18 d1nvma2 88.5 14 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:HMGL-like 19 c2cw6B_ 86.9 12 PDB header:lyase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria 20 c3pueA_ 86.7 16 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of the complex of dhydrodipicolinate synthase from2 acinetobacter baumannii with lysine at 2.6a resolution 21 c3l0gD_ not modelled 86.3 9 PDB header:transferase Chain: D: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of nicotinate-nucleotide pyrophosphorylase from2 ehrlichia chaffeensis at 2.05a resolution 22 d1goxa_ not modelled 86.3 22 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 23 c2ehhE_ not modelled 85.8 15 PDB header:lyase Chain: E: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 aquifex aeolicus 24 c3qjaA_ not modelled 85.4 17 PDB header:lyase Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase; PDBTitle: crystal structure of the mycobacterium tuberculosis indole-3-glycerol2 phosphate synthase (trpc) in apo form 25 d1d3ga_ not modelled 85.3 19 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 26 c3na8A_ not modelled 84.7 12 PDB header:lyase Chain: A: PDB Molecule:putative dihydrodipicolinate synthetase; PDBTitle: crystal structure of a putative dihydrodipicolinate synthetase from2 pseudomonas aeruginosa 27 c1qapA_ not modelled 84.4 14 PDB header:glycosyltransferase Chain: A: PDB Molecule:quinolinic acid phosphoribosyltransferase; PDBTitle: quinolinic acid phosphoribosyltransferase with bound2 quinolinic acid 28 d1uuma_ not modelled 84.1 15 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 29 c3bleA_ not modelled 83.4 11 PDB header:transferase Chain: A: PDB Molecule:citramalate synthase from leptospira interrogans; PDBTitle: crystal structure of the catalytic domain of licms in2 complexed with malonate 30 d1tb3a1 not modelled 83.0 15 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 31 d1geqa_ not modelled 82.9 17 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 32 d1a53a_ not modelled 82.0 12 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 33 d1xxxa1 not modelled 81.8 20 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 34 c2cdh1_ not modelled 81.1 20 PDB header:transferase Chain: 1: PDB Molecule:enoyl reductase; PDBTitle: architecture of the thermomyces lanuginosus fungal fatty2 acid synthase at 5 angstrom resolution. 35 d1o4ua1 not modelled 80.7 12 Fold:TIM beta/alpha-barrel Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like Family:NadC C-terminal domain-like 36 c2vc6A_ not modelled 80.5 16 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: structure of mosa from s. meliloti with pyruvate bound 37 c1x1oC_ not modelled 80.4 14 PDB header:transferase Chain: C: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of project id tt0268 from thermus thermophilus hb8 38 c3cprB_ not modelled 80.3 18 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthetase; PDBTitle: the crystal structure of corynebacterium glutamicum2 dihydrodipicolinate synthase to 2.2 a resolution 39 d1o5ka_ not modelled 80.2 14 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 40 c2zyfA_ not modelled 80.1 11 PDB header:transferase Chain: A: PDB Molecule:homocitrate synthase; PDBTitle: crystal structure of homocitrate synthase from thermus thermophilus2 complexed with magnesuim ion and alpha-ketoglutarate 41 c3tqvA_ not modelled 80.1 9 PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: structure of the nicotinate-nucleotide pyrophosphorylase from2 francisella tularensis. 42 c2e77B_ not modelled 79.4 14 PDB header:oxidoreductase Chain: B: PDB Molecule:lactate oxidase; PDBTitle: crystal structure of l-lactate oxidase with pyruvate complex 43 c3hf3A_ not modelled 79.3 13 PDB header:oxidoreductase Chain: A: PDB Molecule:chromate reductase; PDBTitle: old yellow enzyme from thermus scotoductus sa-01 44 d1qpoa1 not modelled 78.9 11 Fold:TIM beta/alpha-barrel Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like Family:NadC C-terminal domain-like 45 d1rqba2 not modelled 78.8 17 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:HMGL-like 46 c3si9B_ not modelled 78.3 22 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from bartonella2 henselae 47 c3mcnA_ not modelled 78.1 18 PDB header:transferase Chain: A: PDB Molecule:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine PDBTitle: crystal structure of the 6-hyroxymethyl-7,8-dihydropterin2 pyrophosphokinase dihydropteroate synthase bifunctional enzyme from3 francisella tularensis 48 c2rduA_ not modelled 78.0 19 PDB header:oxidoreductase Chain: A: PDB Molecule:hydroxyacid oxidase 1; PDBTitle: crystal structure of human glycolate oxidase in complex with2 glyoxylate 49 c3lciA_ not modelled 77.8 22 PDB header:lyase Chain: A: PDB Molecule:n-acetylneuraminate lyase; PDBTitle: the d-sialic acid aldolase mutant v251w 50 c3pajA_ not modelled 77.5 12 PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase, carboxylating; PDBTitle: 2.00 angstrom resolution crystal structure of a quinolinate2 phosphoribosyltransferase from vibrio cholerae o1 biovar eltor str.3 n16961 51 c2fptA_ not modelled 77.4 18 PDB header:oxidoreductase Chain: A: PDB Molecule:dihydroorotate dehydrogenase, mitochondrial; PDBTitle: dual binding mode of a novel series of dhodh inhibitors 52 c3ivuB_ not modelled 76.6 10 PDB header:transferase Chain: B: PDB Molecule:homocitrate synthase, mitochondrial; PDBTitle: homocitrate synthase lys4 bound to 2-og 53 c2hmcA_ not modelled 75.8 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: the crystal structure of dihydrodipicolinate synthase dapa from2 agrobacterium tumefaciens 54 c3ffsC_ not modelled 75.7 21 PDB header:oxidoreductase Chain: C: PDB Molecule:inosine-5-monophosphate dehydrogenase; PDBTitle: the crystal structure of cryptosporidium parvum inosine-5'-2 monophosphate dehydrogenase 55 c3gr7A_ not modelled 75.5 16 PDB header:oxidoreductase Chain: A: PDB Molecule:nadph dehydrogenase; PDBTitle: structure of oye from geobacillus kaustophilus, hexagonal2 crystal form 56 c1tv5A_ not modelled 74.9 11 PDB header:oxidoreductase Chain: A: PDB Molecule:dihydroorotate dehydrogenase homolog, mitochondrial; PDBTitle: plasmodium falciparum dihydroorotate dehydrogenase with a bound2 inhibitor 57 d1tv5a1 not modelled 74.9 11 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 58 c3d0cB_ not modelled 74.2 12 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 oceanobacillus iheyensis at 1.9 a resolution 59 d2a6na1 not modelled 73.8 15 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 60 d1ep3a_ not modelled 73.7 16 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 61 c3q58A_ not modelled 73.2 15 PDB header:isomerase Chain: A: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase; PDBTitle: structure of n-acetylmannosamine-6-phosphate epimerase from salmonella2 enterica 62 c2rfgB_ not modelled 72.9 22 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from hahella2 chejuensis at 1.5a resolution 63 c3eb2A_ not modelled 72.8 17 PDB header:lyase Chain: A: PDB Molecule:putative dihydrodipicolinate synthetase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 rhodopseudomonas palustris at 2.0a resolution 64 c3gnnA_ not modelled 72.2 9 PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of nicotinate-nucleotide2 pyrophosphorylase from burkholderi pseudomallei 65 c3fkkA_ not modelled 71.6 12 PDB header:lyase Chain: A: PDB Molecule:l-2-keto-3-deoxyarabonate dehydratase; PDBTitle: structure of l-2-keto-3-deoxyarabonate dehydratase 66 c2hl7A_ not modelled 71.0 19 PDB header:oxidoreductase Chain: A: PDB Molecule:cytochrome c-type biogenesis protein ccmh; PDBTitle: crystal structure of the periplasmic domain of ccmh from pseudomonas2 aeruginosa 67 c1qpoA_ not modelled 71.0 10 PDB header:transferase Chain: A: PDB Molecule:quinolinate acid phosphoribosyl transferase; PDBTitle: quinolinate phosphoribosyl transferase (qaprtase) apo-enzyme from2 mycobacterium tuberculosis 68 c3inpA_ not modelled 70.7 13 PDB header:isomerase Chain: A: PDB Molecule:d-ribulose-phosphate 3-epimerase; PDBTitle: 2.05 angstrom resolution crystal structure of d-ribulose-phosphate 3-2 epimerase from francisella tularensis. 69 c3h5dD_ not modelled 70.3 19 PDB header:lyase Chain: D: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: dihydrodipicolinate synthase from drug-resistant streptococcus2 pneumoniae 70 d1xcfa_ not modelled 70.2 12 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 71 c2v9dB_ not modelled 69.4 17 PDB header:lyase Chain: B: PDB Molecule:yage; PDBTitle: crystal structure of yage, a prophage protein belonging to2 the dihydrodipicolinic acid synthase family from e. coli3 k12 72 c3noeA_ not modelled 68.4 17 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from pseudomonas2 aeruginosa 73 d1rd5a_ not modelled 68.2 21 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 74 c3e96B_ not modelled 68.2 16 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 bacillus clausii 75 c3qfeB_ not modelled 68.2 14 PDB header:lyase Chain: B: PDB Molecule:putative dihydrodipicolinate synthase family protein; PDBTitle: crystal structures of a putative dihydrodipicolinate synthase family2 protein from coccidioides immitis 76 c3b4uB_ not modelled 68.1 17 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from agrobacterium2 tumefaciens str. c58 77 c1zfjA_ not modelled 67.5 15 PDB header:oxidoreductase Chain: A: PDB Molecule:inosine monophosphate dehydrogenase; PDBTitle: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from2 streptococcus pyogenes 78 c2ekcA_ not modelled 66.6 21 PDB header:lyase Chain: A: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: structural study of project id aq_1548 from aquifex aeolicus vf5 79 c2r8wB_ not modelled 66.3 14 PDB header:lyase Chain: B: PDB Molecule:agr_c_1641p; PDBTitle: the crystal structure of dihydrodipicolinate synthase (atu0899) from2 agrobacterium tumefaciens str. c58 80 c2yxgD_ not modelled 65.1 17 PDB header:lyase Chain: D: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihyrodipicolinate synthase (dapa) 81 d1vyra_ not modelled 65.0 14 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 82 c3g0sA_ not modelled 64.9 15 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: dihydrodipicolinate synthase from salmonella typhimurium lt2 83 c2jbmA_ not modelled 64.4 17 PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: qprtase structure from human 84 c2c3zA_ not modelled 64.3 12 PDB header:lyase Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase; PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus 85 c3daqB_ not modelled 63.8 17 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from methicillin-2 resistant staphylococcus aureus 86 d1qopa_ not modelled 63.4 18 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 87 d1hl2a_ not modelled 63.4 22 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 88 c3s5oA_ not modelled 62.9 18 PDB header:lyase Chain: A: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase, mitochondrial; PDBTitle: crystal structure of human 4-hydroxy-2-oxoglutarate aldolase bound to2 pyruvate 89 c3bi8A_ not modelled 62.0 16 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: structure of dihydrodipicolinate synthase from clostridium2 botulinum 90 d1f76a_ not modelled 61.4 12 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 91 c1vrdA_ not modelled 61.4 15 PDB header:oxidoreductase Chain: A: PDB Molecule:inosine-5'-monophosphate dehydrogenase; PDBTitle: crystal structure of inosine-5'-monophosphate dehydrogenase (tm1347)2 from thermotoga maritima at 2.18 a resolution 92 d1xi3a_ not modelled 61.3 14 Fold:TIM beta/alpha-barrel Superfamily:Thiamin phosphate synthase Family:Thiamin phosphate synthase 93 c1o4uA_ not modelled 61.3 12 PDB header:transferase Chain: A: PDB Molecule:type ii quinolic acid phosphoribosyltransferase; PDBTitle: crystal structure of a nicotinate nucleotide pyrophosphorylase2 (tm1645) from thermotoga maritima at 2.50 a resolution 94 c3igsB_ not modelled 60.1 12 PDB header:isomerase Chain: B: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase 2; PDBTitle: structure of the salmonella enterica n-acetylmannosamine-6-phosphate2 2-epimerase 95 c2kw0A_ not modelled 59.5 19 PDB header:oxidoreductase Chain: A: PDB Molecule:ccmh protein; PDBTitle: solution structure of n-terminal domain of ccmh from escherichia.coli 96 d1kbla1 not modelled 59.1 14 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate phosphate dikinase, C-terminal domain 97 c3thaB_ not modelled 59.0 15 PDB header:lyase Chain: B: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: tryptophan synthase subunit alpha from campylobacter jejuni. 98 c1me9A_ not modelled 58.8 16 PDB header:oxidoreductase Chain: A: PDB Molecule:inosine-5'-monophosphate dehydrogenase; PDBTitle: inosine monophosphate dehydrogenase (impdh) from2 tritrichomonas foetus with imp bound 99 c2b7pA_ not modelled 58.1 14 PDB header:transferase Chain: A: PDB Molecule:probable nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of quinolinic acid phosphoribosyltransferase from2 helicobacter pylori 100 d1xm3a_ not modelled 57.7 20 Fold:TIM beta/alpha-barrel Superfamily:ThiG-like Family:ThiG-like 101 d1ps9a1 not modelled 55.3 11 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 102 d1ujpa_ not modelled 55.2 18 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 103 c2vefB_ not modelled 54.7 16 PDB header:transferase Chain: B: PDB Molecule:dihydropteroate synthase; PDBTitle: dihydropteroate synthase from streptococcus pneumoniae 104 c1keeH_ not modelled 54.2 18 PDB header:ligase Chain: H: PDB Molecule:carbamoyl-phosphate synthetase small chain; PDBTitle: inactivation of the amidotransferase activity of carbamoyl phosphate2 synthetase by the antibiotic acivicin 105 c2nx9B_ not modelled 54.2 16 PDB header:lyase Chain: B: PDB Molecule:oxaloacetate decarboxylase 2, subunit alpha; PDBTitle: crystal structure of the carboxyltransferase domain of the2 oxaloacetate decarboxylase na+ pump from vibrio cholerae 106 c3n2xB_ not modelled 54.0 16 PDB header:lyase Chain: B: PDB Molecule:uncharacterized protein yage; PDBTitle: crystal structure of yage, a prophage protein belonging to the2 dihydrodipicolinic acid synthase family from e. coli k12 in complex3 with pyruvate 107 c3lerA_ not modelled 53.3 21 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 campylobacter jejuni subsp. jejuni nctc 11168 108 c2a7nA_ not modelled 52.9 15 PDB header:oxidoreductase Chain: A: PDB Molecule:l(+)-mandelate dehydrogenase; PDBTitle: crystal structure of the g81a mutant of the active chimera of (s)-2 mandelate dehydrogenase 109 d1piia2 not modelled 52.8 6 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 110 c1jcnA_ not modelled 51.8 10 PDB header:oxidoreductase Chain: A: PDB Molecule:inosine monophosphate dehydrogenase i; PDBTitle: binary complex of human type-i inosine monophosphate dehydrogenase2 with 6-cl-imp 111 c3tdmD_ not modelled 50.9 23 PDB header:de novo protein Chain: D: PDB Molecule:computationally designed two-fold symmetric tim-barrel PDBTitle: computationally designed tim-barrel protein, halfflr 112 c3khjE_ not modelled 50.0 20 PDB header:oxidoreductase Chain: E: PDB Molecule:inosine-5-monophosphate dehydrogenase; PDBTitle: c. parvum inosine monophosphate dehydrogenase bound by inhibitor c64 113 c3tr9A_ not modelled 49.4 19 PDB header:transferase Chain: A: PDB Molecule:dihydropteroate synthase; PDBTitle: structure of a dihydropteroate synthase (folp) in complex with pteroic2 acid from coxiella burnetii 114 d1vhna_ not modelled 49.2 14 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 115 d1xkya1 not modelled 49.2 20 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 116 d1f74a_ not modelled 49.0 19 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 117 c2nuxB_ not modelled 48.6 23 PDB header:lyase Chain: B: PDB Molecule:2-keto-3-deoxygluconate/2-keto-3-deoxy-6-phospho gluconate PDBTitle: 2-keto-3-deoxygluconate aldolase from sulfolobus acidocaldarius,2 native structure in p6522 at 2.5 a resolution 118 c2yzrB_ not modelled 47.7 24 PDB header:lyase Chain: B: PDB Molecule:pyridoxal biosynthesis lyase pdxs; PDBTitle: crystal structure of pyridoxine biosynthesis protein from2 methanocaldococcus jannaschii 119 c3dz1A_ not modelled 47.7 14 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 rhodopseudomonas palustris at 1.87a resolution 120 d2flia1 not modelled 46.2 18 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0