Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	M	S	E	S	N	K	Q	Q	A	V	N	K	L	T	E	I	V	A	N	F	T	A	M	I	S	T	R	M	P	D	D	V	V	D	K	L	K	Q	L	K	D	A	E	T	S	S	M	G	K	I	I	Y	H	T	M	F	D	N	M
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																																					?		?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Q	K	A	I	D	L	N	R	P	A	C	Q	D	T	G	E	I	M	F	F	V	K	V	G	S	R	F	P	L	L	G	E	L	Q	S	I	L	K	Q	A	V	E	E	A	T	V	K	A	P	L	R	H	N	A	V	E	I	F	D	E
Secondary structure
SS confidence
Disorder																																																													?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	N	T	G	K	N	T	G	S	G	V	P	W	V	T	W	D	I	I	P	D	N	D	D	A	E	I	E	V	Y	M	A	G	G	G	C	T	L	P	G	R	S	K	V	L	M	P	S	E	G	Y	E	G	V	V	K	F	V	F	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		N	I	S	T	L	A	V	N	A	C	P	P	V	L	V	G	V	G	I	A	T	S	V	E	T	A	A	V	L	S	R	K	A	I	L	R	P	I	G	S	R	H	P	N	P	K	A	A	E	L	E	L	R	L	E	E	G	L	N	R
Secondary structure
SS confidence
Disorder						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		L	G	I	G	P	Q	G	L	T	G	N	S	S	V	M	G	V	H	I	E	S	A	A	R	H	P	S	T	I	G	V	A	V	S	T	G	C	W	A	H	R	R	G	T	L	L	V	H	A	D	L	T	F	E	N	L	S	H	T	R
Secondary structure
SS confidence
Disorder																											?																															?	?	?	?
Disorder confidence
		.	.	.
Sequence		S	A	L
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2qv6 chain D Region: 164 - 214 Aligned: 47 Modelled: 51 Confidence: 92.7% Identity: 15% PDB header:hydrolase Chain: D: PDB Molecule:gtp cyclohydrolase iii; PDBTitle: gtp cyclohydrolase iii from m. jannaschii (mj0145)2 complexed with gtp and metal ions Phyre2 PDB 1n0u chain A domain 3 Region: 29 - 110 Aligned: 81 Modelled: 82 Confidence: 72.9% Identity: 14% Fold: Ribosomal protein S5 domain 2-like Superfamily: Ribosomal protein S5 domain 2-like Family: Translational machinery components Phyre2 PDB 1edz chain A domain 2 Region: 172 - 242 Aligned: 70 Modelled: 71 Confidence: 55.0% Identity: 17% Fold: Aminoacid dehydrogenase-like, N-terminal domain Superfamily: Aminoacid dehydrogenase-like, N-terminal domain Family: Tetrahydrofolate dehydrogenase/cyclohydrolase Phyre2 PDB 3p2o chain A Region: 172 - 242 Aligned: 71 Modelled: 71 Confidence: 51.6% Identity: 14% PDB header:oxidoreductase, hydrolase Chain: A: PDB Molecule:bifunctional protein fold; PDBTitle: crystal structure of fold bifunctional protein from campylobacter2 jejuni Phyre2 PDB 3p2o chain B Region: 172 - 242 Aligned: 71 Modelled: 71 Confidence: 46.4% Identity: 14% PDB header:oxidoreductase, hydrolase Chain: B: PDB Molecule:bifunctional protein fold; PDBTitle: crystal structure of fold bifunctional protein from campylobacter2 jejuni Phyre2 PDB 1n9w chain A Region: 112 - 200 Aligned: 76 Modelled: 89 Confidence: 44.6% Identity: 21% PDB header:biosynthetic protein Chain: A: PDB Molecule:aspartyl-trna synthetase 2; PDBTitle: crystal structure of the non-discriminating and archaeal-2 type aspartyl-trna synthetase from thermus thermophilus Phyre2 PDB 1wyd chain B Region: 11 - 200 Aligned: 161 Modelled: 173 Confidence: 43.6% Identity: 16% PDB header:ligase Chain: B: PDB Molecule:hypothetical aspartyl-trna synthetase; PDBTitle: crystal structure of aspartyl-trna synthetase from sulfolobus tokodaii Phyre2 PDB 1a4i chain A domain 2 Region: 172 - 242 Aligned: 71 Modelled: 71 Confidence: 42.6% Identity: 11% Fold: Aminoacid dehydrogenase-like, N-terminal domain Superfamily: Aminoacid dehydrogenase-like, N-terminal domain Family: Tetrahydrofolate dehydrogenase/cyclohydrolase Phyre2 PDB 2c2x chain B Region: 172 - 242 Aligned: 71 Modelled: 71 Confidence: 42.0% Identity: 14% PDB header:oxidoreductase Chain: B: PDB Molecule:methylenetetrahydrofolate dehydrogenase- PDBTitle: three dimensional structure of bifunctional2 methylenetetrahydrofolate dehydrogenase-cyclohydrolase3 from mycobacterium tuberculosis Phyre2 PDB 3l07 chain B Region: 172 - 242 Aligned: 71 Modelled: 71 Confidence: 41.7% Identity: 17% PDB header:oxidoreductase,hydrolase Chain: B: PDB Molecule:bifunctional protein fold; PDBTitle: methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate2 cyclohydrolase, putative bifunctional protein fold from francisella3 tularensis. Phyre2 PDB 3mcp chain A Region: 134 - 204 Aligned: 69 Modelled: 68 Confidence: 41.5% Identity: 7% PDB header:transferase Chain: A: PDB Molecule:glucokinase; PDBTitle: crystal structure of glucokinase (bdi_1628) from parabacteroides2 distasonis atcc 8503 at 3.00 a resolution Phyre2 PDB 1x55 chain A Region: 112 - 200 Aligned: 79 Modelled: 89 Confidence: 40.2% Identity: 18% PDB header:ligase Chain: A: PDB Molecule:asparaginyl-trna synthetase; PDBTitle: crystal structure of asparaginyl-trna synthetase from pyrococcus2 horikoshii complexed with asparaginyl-adenylate analogue Phyre2 PDB 1n9w chain A domain 2 Region: 112 - 200 Aligned: 76 Modelled: 89 Confidence: 37.4% Identity: 20% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 PDB 2ap1 chain A domain 2 Region: 138 - 201 Aligned: 62 Modelled: 64 Confidence: 36.1% Identity: 18% Fold: Ribonuclease H-like motif Superfamily: Actin-like ATPase domain Family: ROK Phyre2 PDB 1edz chain A Region: 172 - 242 Aligned: 70 Modelled: 71 Confidence: 32.6% Identity: 17% PDB header:oxidoreductase Chain: A: PDB Molecule:5,10-methylenetetrahydrofolate dehydrogenase; PDBTitle: structure of the nad-dependent 5,10-2 methylenetetrahydrofolate dehydrogenase from saccharomyces3 cerevisiae Phyre2 PDB 1b8a chain B Region: 11 - 200 Aligned: 160 Modelled: 173 Confidence: 32.1% Identity: 14% PDB header:ligase Chain: B: PDB Molecule:protein (aspartyl-trna synthetase); PDBTitle: aspartyl-trna synthetase Phyre2 PDB 2jfs chain A Region: 193 - 272 Aligned: 80 Modelled: 80 Confidence: 30.3% Identity: 11% PDB header:hydrolase Chain: A: PDB Molecule:ser-thr phosphatase mspp; PDBTitle: crystal structure of the ppm ser-thr phosphatase mspp from2 mycobacterium smegmatis in complex with cacodylate Phyre2 PDB 1hl2 chain A Region: 175 - 243 Aligned: 67 Modelled: 69 Confidence: 29.7% Identity: 15% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 1ei5 chain A domain 2 Region: 271 - 286 Aligned: 16 Modelled: 16 Confidence: 27.0% Identity: 31% Fold: Streptavidin-like Superfamily: D-aminopeptidase, middle and C-terminal domains Family: D-aminopeptidase, middle and C-terminal domains Phyre2 PDB 3chv chain A Region: 173 - 246 Aligned: 70 Modelled: 74 Confidence: 26.3% Identity: 17% PDB header:metal binding protein Chain: A: PDB Molecule:prokaryotic domain of unknown function (duf849) with a tim PDBTitle: crystal structure of a prokaryotic domain of unknown function (duf849)2 member (spoa0042) from silicibacter pomeroyi dss-3 at 1.45 a3 resolution Phyre2 1 c2qv6D_ 2 d1n0ua3 3 d1edza2 4 c3p2oA_ 5 c3p2oB_ 6 c1n9wA_ 7 c1wydB_ 8 d1a4ia2 9 c2c2xB_ 10 c3l07B_ 11 c3mcpA_ 12 c1x55A_ 13 d1n9wa2 14 d2ap1a2 15 c1edzA_ 16 c1b8aB_ 17 c2jfsA_ 18 d1hl2a_ 19 d1ei5a2 20 c3chvA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2qv6D_ 92.7 15 PDB header:hydrolase Chain: D: PDB Molecule:gtp cyclohydrolase iii; PDBTitle: gtp cyclohydrolase iii from m. jannaschii (mj0145)2 complexed with gtp and metal ions 2 d1n0ua3 72.9 14 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:Translational machinery components 3 d1edza2 55.0 17 Fold:Aminoacid dehydrogenase-like, N-terminal domain Superfamily:Aminoacid dehydrogenase-like, N-terminal domain Family:Tetrahydrofolate dehydrogenase/cyclohydrolase 4 c3p2oA_ 51.6 14 PDB header:oxidoreductase, hydrolase Chain: A: PDB Molecule:bifunctional protein fold; PDBTitle: crystal structure of fold bifunctional protein from campylobacter2 jejuni 5 c3p2oB_ 46.4 14 PDB header:oxidoreductase, hydrolase Chain: B: PDB Molecule:bifunctional protein fold; PDBTitle: crystal structure of fold bifunctional protein from campylobacter2 jejuni 6 c1n9wA_ 44.6 21 PDB header:biosynthetic protein Chain: A: PDB Molecule:aspartyl-trna synthetase 2; PDBTitle: crystal structure of the non-discriminating and archaeal-2 type aspartyl-trna synthetase from thermus thermophilus 7 c1wydB_ 43.6 16 PDB header:ligase Chain: B: PDB Molecule:hypothetical aspartyl-trna synthetase; PDBTitle: crystal structure of aspartyl-trna synthetase from sulfolobus tokodaii 8 d1a4ia2 42.6 11 Fold:Aminoacid dehydrogenase-like, N-terminal domain Superfamily:Aminoacid dehydrogenase-like, N-terminal domain Family:Tetrahydrofolate dehydrogenase/cyclohydrolase 9 c2c2xB_ 42.0 14 PDB header:oxidoreductase Chain: B: PDB Molecule:methylenetetrahydrofolate dehydrogenase- PDBTitle: three dimensional structure of bifunctional2 methylenetetrahydrofolate dehydrogenase-cyclohydrolase3 from mycobacterium tuberculosis 10 c3l07B_ 41.7 17 PDB header:oxidoreductase,hydrolase Chain: B: PDB Molecule:bifunctional protein fold; PDBTitle: methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate2 cyclohydrolase, putative bifunctional protein fold from francisella3 tularensis. 11 c3mcpA_ 41.5 7 PDB header:transferase Chain: A: PDB Molecule:glucokinase; PDBTitle: crystal structure of glucokinase (bdi_1628) from parabacteroides2 distasonis atcc 8503 at 3.00 a resolution 12 c1x55A_ 40.2 18 PDB header:ligase Chain: A: PDB Molecule:asparaginyl-trna synthetase; PDBTitle: crystal structure of asparaginyl-trna synthetase from pyrococcus2 horikoshii complexed with asparaginyl-adenylate analogue 13 d1n9wa2 37.4 20 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 14 d2ap1a2 36.1 18 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:ROK 15 c1edzA_ 32.6 17 PDB header:oxidoreductase Chain: A: PDB Molecule:5,10-methylenetetrahydrofolate dehydrogenase; PDBTitle: structure of the nad-dependent 5,10-2 methylenetetrahydrofolate dehydrogenase from saccharomyces3 cerevisiae 16 c1b8aB_ 32.1 14 PDB header:ligase Chain: B: PDB Molecule:protein (aspartyl-trna synthetase); PDBTitle: aspartyl-trna synthetase 17 c2jfsA_ 30.3 11 PDB header:hydrolase Chain: A: PDB Molecule:ser-thr phosphatase mspp; PDBTitle: crystal structure of the ppm ser-thr phosphatase mspp from2 mycobacterium smegmatis in complex with cacodylate 18 d1hl2a_ 29.7 15 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 19 d1ei5a2 27.0 31 Fold:Streptavidin-like Superfamily:D-aminopeptidase, middle and C-terminal domains Family:D-aminopeptidase, middle and C-terminal domains 20 c3chvA_ 26.3 17 PDB header:metal binding protein Chain: A: PDB Molecule:prokaryotic domain of unknown function (duf849) with a tim PDBTitle: crystal structure of a prokaryotic domain of unknown function (duf849)2 member (spoa0042) from silicibacter pomeroyi dss-3 at 1.45 a3 resolution 21 c2j0eA_ not modelled 25.2 32 PDB header:hydrolase Chain: A: PDB Molecule:6-phosphogluconolactonase; PDBTitle: three dimensional structure and catalytic mechanism of 6-2 phosphogluconolactonase from trypanosoma brucei 22 d1lfba_ not modelled 24.2 14 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Homeodomain-like Family:Homeodomain 23 c3dz1A_ not modelled 23.9 25 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 rhodopseudomonas palustris at 1.87a resolution 24 c1a4iB_ not modelled 23.6 11 PDB header:oxidoreductase Chain: B: PDB Molecule:methylenetetrahydrofolate dehydrogenase / PDBTitle: human tetrahydrofolate dehydrogenase / cyclohydrolase 25 d1gkub1 not modelled 23.3 17 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Helicase-like "domain" of reverse gyrase 26 c1pbtA_ not modelled 23.0 25 PDB header:hydrolase, oxidoreductase Chain: A: PDB Molecule:6-phosphogluconolactonase; PDBTitle: the crystal structure of tm1154, oxidoreductase, sol/devb2 family from thermotoga maritima 27 d1js3a_ not modelled 22.1 20 Fold:PLP-dependent transferase-like Superfamily:PLP-dependent transferases Family:Pyridoxal-dependent decarboxylase 28 c3orsD_ not modelled 21.0 14 PDB header:isomerase,biosynthetic protein Chain: D: PDB Molecule:n5-carboxyaminoimidazole ribonucleotide mutase; PDBTitle: crystal structure of n5-carboxyaminoimidazole ribonucleotide mutase2 from staphylococcus aureus 29 d1fyba1 not modelled 20.5 32 Fold:Plant proteinase inhibitors Superfamily:Plant proteinase inhibitors Family:Plant proteinase inhibitors 30 d1tiha_ not modelled 19.0 32 Fold:Plant proteinase inhibitors Superfamily:Plant proteinase inhibitors Family:Plant proteinase inhibitors 31 c2k4mA_ not modelled 18.6 9 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:upf0146 protein mth_1000; PDBTitle: solution nmr structure of m. thermoautotrophicum protein2 mth_1000, northeast structural genomics consortium target3 tr8 32 d1pjua1 not modelled 18.5 14 Fold:Plant proteinase inhibitors Superfamily:Plant proteinase inhibitors Family:Plant proteinase inhibitors 33 d4sgbi_ not modelled 18.3 29 Fold:Plant proteinase inhibitors Superfamily:Plant proteinase inhibitors Family:Plant proteinase inhibitors 34 d1j2pa_ not modelled 17.9 13 Fold:Ntn hydrolase-like Superfamily:N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family:Proteasome subunits 35 c3trhI_ not modelled 17.7 16 PDB header:lyase Chain: I: PDB Molecule:phosphoribosylaminoimidazole carboxylase PDBTitle: structure of a phosphoribosylaminoimidazole carboxylase catalytic2 subunit (pure) from coxiella burnetii 36 d1ce3a_ not modelled 17.3 33 Fold:Plant proteinase inhibitors Superfamily:Plant proteinase inhibitors Family:Plant proteinase inhibitors 37 d1yqea1 not modelled 17.2 16 Fold:Phosphorylase/hydrolase-like Superfamily:AF0625-like Family:AF0625-like 38 d1c0aa3 not modelled 16.9 19 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 39 d2oz4a1 not modelled 16.6 29 Fold:Immunoglobulin-like beta-sandwich Superfamily:Immunoglobulin Family:C2 set domains 40 c3c00B_ not modelled 16.4 11 PDB header:membrane protein, protein transport Chain: B: PDB Molecule:escu; PDBTitle: crystal structural of the mutated g247t escu/spas c-terminal domain 41 c2dzaA_ not modelled 16.3 20 PDB header:transferase Chain: A: PDB Molecule:dihydropteroate synthase; PDBTitle: crystal structure of dihydropteroate synthase from thermus2 thermophilus hb8 in complex with 4-aminobenzoate 42 c3cssA_ not modelled 15.8 32 PDB header:hydrolase Chain: A: PDB Molecule:6-phosphogluconolactonase; PDBTitle: crystal structure of 6-phosphogluconolactonase from leishmania2 guyanensis 43 c3fiuD_ not modelled 15.8 18 PDB header:ligase Chain: D: PDB Molecule:nh(3)-dependent nad(+) synthetase; PDBTitle: structure of nmn synthetase from francisella tularensis 44 c3gv1A_ not modelled 15.8 9 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:disulfide interchange protein; PDBTitle: crystal structure of disulfide interchange protein from neisseria2 gonorrhoeae 45 c2jlhA_ not modelled 15.7 8 PDB header:protein transport Chain: A: PDB Molecule:yop proteins translocation protein u; PDBTitle: crystal structure of the cytoplasmic domain of yersinia2 pestis yscu n263a mutant 46 c4a5oB_ not modelled 15.2 13 PDB header:oxidoreductase Chain: B: PDB Molecule:bifunctional protein fold; PDBTitle: crystal structure of pseudomonas aeruginosa n5, n10-2 methylenetetrahydrofolate dehydrogenase-cyclohydrolase (fold) 47 d1u11a_ not modelled 15.1 9 Fold:Flavodoxin-like Superfamily:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) Family:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) 48 d1j6xa_ not modelled 14.9 8 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:Autoinducer-2 production protein LuxS 49 d2g39a2 not modelled 14.8 9 Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:CoA transferase alpha subunit-like 50 d1xmpa_ not modelled 14.8 12 Fold:Flavodoxin-like Superfamily:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) Family:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) 51 c3hhdC_ not modelled 14.5 13 PDB header:transferase, hydrolase Chain: C: PDB Molecule:fatty acid synthase; PDBTitle: structure of the human fatty acid synthase ks-mat didomain2 as a framework for inhibitor design. 52 c3fp5A_ not modelled 14.5 14 PDB header:lipid binding protein Chain: A: PDB Molecule:acyl-coa binding protein; PDBTitle: crystal structure of acbp from moniliophthora perniciosa 53 c2fw9A_ not modelled 14.3 9 PDB header:lyase Chain: A: PDB Molecule:n5-carboxyaminoimidazole ribonucleotide mutase; PDBTitle: structure of pure (n5-carboxyaminoimidazole ribonucleotide mutase)2 h59f from the acidophilic bacterium acetobacter aceti, at ph 8 54 c3icoA_ not modelled 14.1 30 PDB header:hydrolase Chain: A: PDB Molecule:6-phosphogluconolactonase; PDBTitle: crystal structure of 6-phosphogluconolactonase from2 mycobacterium tuberculosis 55 c3c8lB_ not modelled 14.0 22 PDB header:unknown function Chain: B: PDB Molecule:ftsz-like protein of unknown function; PDBTitle: crystal structure of a ftsz-like protein of unknown function2 (npun_r1471) from nostoc punctiforme pcc 73102 at 1.22 a resolution 56 c1y89B_ not modelled 13.9 25 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:devb protein; PDBTitle: crystal structure of devb protein 57 c3i7fA_ not modelled 13.8 14 PDB header:ligase Chain: A: PDB Molecule:aspartyl-trna synthetase; PDBTitle: aspartyl trna synthetase from entamoeba histolytica 58 d1b0aa2 not modelled 13.7 20 Fold:Aminoacid dehydrogenase-like, N-terminal domain Superfamily:Aminoacid dehydrogenase-like, N-terminal domain Family:Tetrahydrofolate dehydrogenase/cyclohydrolase 59 d1bbua2 not modelled 13.6 35 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 60 c3kz4A_ not modelled 13.4 15 PDB header:virus Chain: A: PDB Molecule:inner capsid protein vp2; PDBTitle: crystal structure of the rotavirus double layered particle 61 c3gzuB_ not modelled 12.9 15 PDB header:virus Chain: B: PDB Molecule:inner capsid protein vp2; PDBTitle: vp7 recoated rotavirus dlp 62 c2oxcA_ not modelled 12.8 13 PDB header:hydrolase Chain: A: PDB Molecule:probable atp-dependent rna helicase ddx20; PDBTitle: human dead-box rna helicase ddx20, dead domain in complex2 with adp 63 c2oqjF_ not modelled 12.8 71 PDB header:immune system Chain: F: PDB Molecule:peptide 2g12.1 (acppshvldmrsgtclaaegk); PDBTitle: crystal structure analysis of fab 2g12 in complex with peptide 2g12.1 64 c3no5C_ not modelled 12.7 23 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a pfam duf849 domain containing protein2 (reut_a1631) from ralstonia eutropha jmp134 at 1.90 a resolution 65 c3gykC_ not modelled 12.5 20 PDB header:oxidoreductase Chain: C: PDB Molecule:27kda outer membrane protein; PDBTitle: the crystal structure of a thioredoxin-like oxidoreductase from2 silicibacter pomeroyi dss-3 66 c2imeA_ not modelled 12.4 11 PDB header:transferase Chain: A: PDB Molecule:2-hydroxychromene-2-carboxylate isomerase; PDBTitle: 2-hydroxychromene-2-carboxylate isomerase: a kappa class glutathione-2 s-transferase from pseudomonas putida 67 d1l0wa3 not modelled 12.0 15 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 68 d1w3ia_ not modelled 11.9 15 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 69 c4a26B_ not modelled 11.9 14 PDB header:oxidoreductase Chain: B: PDB Molecule:putative c-1-tetrahydrofolate synthase, cytoplasmic; PDBTitle: the crystal structure of leishmania major n5,n10-2 methylenetetrahydrofolate dehydrogenase/cyclohydrolase 70 c2oqjL_ not modelled 11.7 71 PDB header:immune system Chain: L: PDB Molecule:peptide 2g12.1 (acppshvldmrsgtclaaegk); PDBTitle: crystal structure analysis of fab 2g12 in complex with peptide 2g12.1 71 c2oqjI_ not modelled 11.7 71 PDB header:immune system Chain: I: PDB Molecule:peptide 2g12.1 (acppshvldmrsgtclaaegk); PDBTitle: crystal structure analysis of fab 2g12 in complex with peptide 2g12.1 72 c2oqjC_ not modelled 11.6 71 PDB header:immune system Chain: C: PDB Molecule:peptide 2g12.1 (acppshvldmrsgtclaaegk); PDBTitle: crystal structure analysis of fab 2g12 in complex with peptide 2g12.1 73 c2k5jB_ not modelled 11.5 11 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein yiif; PDBTitle: solution structure of protein yiif from shigella flexneri2 serotype 5b (strain 8401) . northeast structural genomics3 consortium target sft1 74 c3n2xB_ not modelled 11.4 22 PDB header:lyase Chain: B: PDB Molecule:uncharacterized protein yage; PDBTitle: crystal structure of yage, a prophage protein belonging to the2 dihydrodipicolinic acid synthase family from e. coli k12 in complex3 with pyruvate 75 d1ze3h1 not modelled 11.2 7 Fold:Common fold of diphtheria toxin/transcription factors/cytochrome f Superfamily:Bacterial adhesins Family:Pilus subunits 76 d1oyvi_ not modelled 11.2 14 Fold:Plant proteinase inhibitors Superfamily:Plant proteinase inhibitors Family:Plant proteinase inhibitors 77 c3t7yB_ not modelled 11.1 7 PDB header:protein transport Chain: B: PDB Molecule:yop proteins translocation protein u; PDBTitle: structure of an autocleavage-inactive mutant of the cytoplasmic domain2 of ct091, the yscu homologue of chlamydia trachomatis 78 d1rq2a2 not modelled 11.0 28 Fold:Bacillus chorismate mutase-like Superfamily:Tubulin C-terminal domain-like Family:Tubulin, C-terminal domain 79 d1xkya1 not modelled 10.7 18 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 80 d1y74a1 not modelled 10.7 15 Fold:L27 domain Superfamily:L27 domain Family:L27 domain 81 c1fybA_ not modelled 10.7 33 PDB header:hydrolase inhibitor Chain: A: PDB Molecule:proteinase inhibitor; PDBTitle: solution structure of c1-t1, a two-domain proteinase2 inhibitor derived from the circular precursor protein na-3 propi from nicotiana alata 82 d1z6ma1 not modelled 10.6 8 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:DsbA-like 83 d1nnha_ not modelled 10.6 25 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 84 c3fluD_ not modelled 10.5 26 PDB header:lyase Chain: D: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from the pathogen2 neisseria meningitidis 85 d1u6za3 not modelled 10.5 14 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Ppx/GppA phosphatase 86 d1eova2 not modelled 10.3 30 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 87 c3aq3A_ not modelled 10.3 11 PDB header:toxin Chain: A: PDB Molecule:6b protein; PDBTitle: molecular insights into plant cell proliferation disturbance by2 agrobacterium protein 6b 88 c3c01H_ not modelled 10.3 11 PDB header:membrane protein, protein transport Chain: H: PDB Molecule:surface presentation of antigens protein spas; PDBTitle: crystal structural of native spas c-terminal domain 89 c3dpiA_ not modelled 10.0 23 PDB header:ligase Chain: A: PDB Molecule:nad+ synthetase; PDBTitle: crystal structure of nad+ synthetase from burkholderia pseudomallei 90 c3r6aB_ not modelled 9.9 16 PDB header:isomerase, lyase Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of an uncharacterized protein (hypothetical protein2 mm_3218) from methanosarcina mazei. 91 d2zdra2 not modelled 9.8 26 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:NeuB-like 92 c3eb2A_ not modelled 9.5 24 PDB header:lyase Chain: A: PDB Molecule:putative dihydrodipicolinate synthetase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 rhodopseudomonas palustris at 2.0a resolution 93 c3qw4B_ not modelled 9.4 22 PDB header:transferase, lyase Chain: B: PDB Molecule:ump synthase; PDBTitle: structure of leishmania donovani ump synthase 94 d2f6ua1 not modelled 9.3 22 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 95 c2xgtB_ not modelled 9.3 17 PDB header:ligase Chain: B: PDB Molecule:asparaginyl-trna synthetase, cytoplasmic; PDBTitle: asparaginyl-trna synthetase from brugia malayi complexed2 with the sulphamoyl analogue of asparaginyl-adenylate 96 c3pr3B_ not modelled 9.2 30 PDB header:isomerase Chain: B: PDB Molecule:glucose-6-phosphate isomerase; PDBTitle: crystal structure of plasmodium falciparum glucose-6-phosphate2 isomerase (pf14_0341) in complex with fructose-6-phosphate 97 d1rypb_ not modelled 9.2 18 Fold:Ntn hydrolase-like Superfamily:N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family:Proteasome subunits 98 c2vt1B_ not modelled 9.1 9 PDB header:membrane protein Chain: B: PDB Molecule:surface presentation of antigens protein spas; PDBTitle: crystal structure of the cytoplasmic domain of spa40, the2 specificity switch for the shigella flexneri type iii3 secretion system 99 c2kl0A_ not modelled 8.9 29 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative thiamin biosynthesis this; PDBTitle: solution nmr structure of rhodopseudomonas palustris rpa3574,2 northeast structural genomics consortium (nesg) target rpr325

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0