Phyre 2 Results for P0AES4

Phyre Home | Retrieve Phyre Job Id

Email | l.a.kelley@imperial.ac.uk
Description | P0AES4
Date | Thu Jan 5 11:24:06 GMT 2012
Unique Job ID | 8a01775cad7e4659

Summary |

Top model
Image coloured by rainbow N → C terminus
| Close Jmol

Model (left) based on template c1zvuA_
Top template information
PDB header:isomerase Chain: A: PDB Molecule:topoisomerase iv subunit a; PDBTitle: structure of the full-length e. coli parc subunit
Confidence and coverage
Confidence: | 100.0% | Coverage: | 76%
669 residues ( 76% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
760 residues ( 87%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | S | D | L | A | R | E | I | T | P | V | N | I | E | E | E | L | K | S | S | Y | L | D | Y | A | M | S | V | I | V | G | R | A | L | P | D | V | R | D | G | L | K | P | V | H | R | R | V | L | Y | A | M | N | V | L | G | N | D | W | N
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | K | A | Y | K | K | S | A | R | V | V | G | D | V | I | G | K | Y | H | P | H | G | D | S | A | V | Y | D | T | I | V | R | M | A | Q | P | F | S | L | R | Y | M | L | V | D | G | Q | G | N | F | G | S | I | D | G | D | S | A | A | A | M
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? |  | ? |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | R | Y | T | E | I | R | L | A | K | I | A | H | E | L | M | A | D | L | E | K | E | T | V | D | F | V | D | N | Y | D | G | T | E | K | I | P | D | V | M | P | T | K | I | P | N | L | L | V | N | G | S | S | G | I | A | V | G | M | A | T
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240
Sequence |  | N | I | P | P | H | N | L | T | E | V | I | N | G | C | L | A | Y | I | D | D | E | D | I | S | I | E | G | L | M | E | H | I | P | G | P | D | F | P | T | A | A | I | I | N | G | R | R | G | I | E | E | A | Y | R | T | G | R | G | K | V
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300
Sequence |  | Y | I | R | A | R | A | E | V | E | V | D | A | K | T | G | R | E | T | I | I | V | H | E | I | P | Y | Q | V | N | K | A | R | L | I | E | K | I | A | E | L | V | K | E | K | R | V | E | G | I | S | A | L | R | D | E | S | D | K | D | G
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360
Sequence |  | M | R | I | V | I | E | V | K | R | D | A | V | G | E | V | V | L | N | N | L | Y | S | Q | T | Q | L | Q | V | S | F | G | I | N | M | V | A | L | H | H | G | Q | P | K | I | M | N | L | K | D | I | I | A | A | F | V | R | H | R | R | E
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420
Sequence |  | V | V | T | R | R | T | I | F | E | L | R | K | A | R | D | R | A | H | I | L | E | A | L | A | V | A | L | A | N | I | D | P | I | I | E | L | I | R | H | A | P | T | P | A | E | A | K | T | A | L | V | A | N | P | W | Q | L | G | N | V
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480
Sequence |  | A | A | M | L | E | R | A | G | D | D | A | A | R | P | E | W | L | E | P | E | F | G | V | R | D | G | L | Y | Y | L | T | E | Q | Q | A | Q | A | I | L | D | L | R | L | Q | K | L | T | G | L | E | H | E | K | L | L | D | E | Y | K | E
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540
Sequence |  | L | L | D | Q | I | A | E | L | L | R | I | L | G | S | A | D | R | L | M | E | V | I | R | E | E | L | E | L | V | R | E | Q | F | G | D | K | R | R | T | E | I | T | A | N | S | A | D | I | N | L | E | D | L | I | T | Q | E | D | V | V
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600
Sequence |  | V | T | L | S | H | Q | G | Y | V | K | Y | Q | P | L | S | E | Y | E | A | Q | R | R | G | G | K | G | K | S | A | A | R | I | K | E | E | D | F | I | D | R | L | L | V | A | N | T | H | D | H | I | L | C | F | S | S | R | G | R | V | Y
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660
Sequence |  | S | M | K | V | Y | Q | L | P | E | A | T | R | G | A | R | G | R | P | I | V | N | L | L | P | L | E | Q | D | E | R | I | T | A | I | L | P | V | T | E | F | E | E | G | V | K | V | F | M | A | T | A | N | G | T | V | K | K | T | V | L
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720
Sequence |  | T | E | F | N | R | L | R | T | A | G | K | V | A | I | K | L | V | D | G | D | E | L | I | G | V | D | L | T | S | G | E | D | E | V | M | L | F | S | A | E | G | K | V | V | R | F | K | E | S | S | V | R | A | M | G | C | N | T | T | G
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? |  | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | . | . | . | . | . | . | 760 | . | . | . | . | . | . | . | . | . | 770 | . | . | . | . | . | . | . | . | . | 780
Sequence |  | V | R | G | I | R | L | G | E | G | D | K | V | V | S | L | I | V | P | R | G | D | G | A | I | L | T | A | T | Q | N | G | Y | G | K | R | T | A | V | A | E | Y | P | T | K | S | R | A | T | K | G | V | I | S | I | K | V | T | E | R | N
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  | ? |  | ? | ? | ? | ? |  | ? |  |  |  |  |  |  |  |  |  |  |  | ? | ? |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 790 | . | . | . | . | . | . | . | . | . | 800 | . | . | . | . | . | . | . | . | . | 810 | . | . | . | . | . | . | . | . | . | 820 | . | . | . | . | . | . | . | . | . | 830 | . | . | . | . | . | . | . | . | . | 840
Sequence |  | G | L | V | V | G | A | V | Q | V | D | D | C | D | Q | I | M | M | I | T | D | A | G | T | L | V | R | T | R | V | S | E | I | S | I | V | G | R | N | T | Q | G | V | I | L | I | R | T | A | E | D | E | N | V | V | G | L | Q | R | V | A
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 850 | . | . | . | . | . | . | . | . | . | 860 | . | . | . | . | . | . | . | . | . | 870 | . | . | . | . | .
Sequence |  | E | P | V | D | E | E | D | L | D | T | I | D | G | S | A | A | E | G | D | D | E | I | A | P | E | V | D | V | D | D | E | P | E | E | E
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? |  |  | ? | ? | ? | ? | ? |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| c1zvuA_ |

### PDB 1zvu chain A

Region: 31 - 784
Aligned: 669
Modelled: 695
Confidence: 100.0%
Identity: 36%
PDB header:isomerase
Chain: A: PDB Molecule:topoisomerase iv subunit a;
PDBTitle: structure of the full-length e. coli parc subunit

Phyre2
2 |
| c2wl2B_ |

### PDB 2wl2 chain B

Region: 13 - 522
Aligned: 506
Modelled: 510
Confidence: 100.0%
Identity: 99%
PDB header:isomerase
Chain: B: PDB Molecule:dna gyrase subunit a;
PDBTitle: crystal structure of n-terminal domain of gyra with the2 antibiotic simocyclinone d8

Phyre2
3 |
| c2xcsD_ |

### PDB 2xcs chain D

Region: 9 - 522
Aligned: 479
Modelled: 480
Confidence: 100.0%
Identity: 60%
PDB header:isomerase
Chain: D: PDB Molecule:dna gyrase subunit b, dna gyrase subunit a;
PDBTitle: the 2.1a crystal structure of s. aureus gyrase complex with gsk2994232 and dna

Phyre2
4 |
| c3ifzA_ |

### PDB 3ifz chain A

Region: 2 - 522
Aligned: 482
Modelled: 487
Confidence: 100.0%
Identity: 52%
PDB header:isomerase
Chain: A: PDB Molecule:dna gyrase subunit a;
PDBTitle: crystal structure of the first part of the mycobacterium tuberculosis2 dna gyrase reaction core: the breakage and reunion domain at 2.7 a3 resolution

Phyre2
5 |
| d1ab4a_ |

### PDB 1ab4 chain A

Region: 30 - 522
Aligned: 477
Modelled: 487
Confidence: 100.0%
Identity: 98%
Fold: Type II DNA topoisomerase
Superfamily: Type II DNA topoisomerase
Family: Type II DNA topoisomerase

Phyre2
6 |
| c2xcqA_ |

### PDB 2xcq chain A

Region: 1 - 522
Aligned: 474
Modelled: 488
Confidence: 100.0%
Identity: 60%
PDB header:isomerase
Chain: A: PDB Molecule:dna gyrase subunit b, dna gyrase subunit a;
PDBTitle: the 2.98a crystal structure of the catalytic core (b'a'2 region) of staphylococcus aureus dna gyrase

Phyre2
7 |
| c3ilwA_ |

### PDB 3ilw chain A

Region: 30 - 523
Aligned: 459
Modelled: 460
Confidence: 100.0%
Identity: 51%
PDB header:isomerase
Chain: A: PDB Molecule:dna gyrase subunit a;
PDBTitle: structure of dna gyrase subunit a n-terminal domain

Phyre2
8 |
| c2xkjE_ |

### PDB 2xkj chain E

Region: 9 - 530
Aligned: 479
Modelled: 488
Confidence: 100.0%
Identity: 41%
PDB header:isomerase
Chain: E: PDB Molecule:topoisomerase iv;
PDBTitle: crystal structure of catalytic core of a. baumannii topo iv2 (pare-parc fusion truncate)

Phyre2
9 |
| c2inrA_ |

### PDB 2inr chain A

Region: 33 - 527
Aligned: 442
Modelled: 461
Confidence: 100.0%
Identity: 50%
PDB header:isomerase
Chain: A: PDB Molecule:dna topoisomerase 4 subunit a;
PDBTitle: crystal structure of a 59 kda fragment of topoisomerase iv subunit a2 (grla) from staphylococcus aureus

Phyre2
10 |
| c2novD_ |

### PDB 2nov chain D

Region: 33 - 521
Aligned: 440
Modelled: 453
Confidence: 100.0%
Identity: 47%
PDB header:isomerase
Chain: D: PDB Molecule:dna topoisomerase 4 subunit a;
PDBTitle: breakage-reunion domain of s.pneumoniae topo iv: crystal2 structure of a gram-positive quinolone target

Phyre2
11 |
| c3qx3B_ |

### PDB 3qx3 chain B

Region: 3 - 516
Aligned: 449
Modelled: 480
Confidence: 100.0%
Identity: 25%
PDB header:isomerase/dna/isomerase inhibitor
Chain: B: PDB Molecule:dna topoisomerase 2-beta;
PDBTitle: human topoisomerase iibeta in complex with dna and etoposide

Phyre2
12 |
| c1bjtA_ |

### PDB 1bjt chain A

Region: 12 - 517
Aligned: 458
Modelled: 486
Confidence: 100.0%
Identity: 21%
PDB header:topoisomerase
Chain: A: PDB Molecule:topoisomerase ii;
PDBTitle: topoisomerase ii residues 409-1201

Phyre2
13 |
| d1bjta_ |

### PDB 1bjt chain A

Region: 12 - 517
Aligned: 458
Modelled: 486
Confidence: 100.0%
Identity: 21%
Fold: Type II DNA topoisomerase
Superfamily: Type II DNA topoisomerase
Family: Type II DNA topoisomerase

Phyre2
14 |
| c3l6vA_ |

### PDB 3l6v chain A

Region: 532 - 843
Aligned: 312
Modelled: 312
Confidence: 100.0%
Identity: 59%
PDB header:isomerase
Chain: A: PDB Molecule:dna gyrase subunit a;
PDBTitle: crystal structure of the xanthomonas campestris gyrase a c-2 terminal domain

Phyre2
15 |
| d1wp5a_ |

### PDB 1wp5 chain A

Region: 534 - 849
Aligned: 311
Modelled: 316
Confidence: 100.0%
Identity: 31%
Fold: 6-bladed beta-propeller
Superfamily: GyrA/ParC C-terminal domain-like
Family: GyrA/ParC C-terminal domain-like

Phyre2
16 |
| d1suua_ |

### PDB 1suu chain A

Region: 537 - 839
Aligned: 291
Modelled: 303
Confidence: 100.0%
Identity: 28%
Fold: 6-bladed beta-propeller
Superfamily: GyrA/ParC C-terminal domain-like
Family: GyrA/ParC C-terminal domain-like

Phyre2
17 |
| c1zi0A_ |

### PDB 1zi0 chain A

Region: 536 - 841
Aligned: 286
Modelled: 286
Confidence: 100.0%
Identity: 99%
PDB header:isomerase, dna bindng protein
Chain: A: PDB Molecule:dna gyrase subunit a;
PDBTitle: a superhelical spiral in escherichia coli dna gyrase a c-2 terminal domain imparts unidirectional supercoiling bias

Phyre2
18 |
| c3no0B_ |

### PDB 3no0 chain B

Region: 539 - 841
Aligned: 272
Modelled: 287
Confidence: 100.0%
Identity: 24%
PDB header:isomerase
Chain: B: PDB Molecule:dna gyrase subunit a;
PDBTitle: aquifex aeolicus type iia topoisomerase c-terminal domain

Phyre2
19 |
| c1zvtA_ |

### PDB 1zvt chain A

Region: 536 - 788
Aligned: 237
Modelled: 253
Confidence: 100.0%
Identity: 18%
PDB header:isomerase
Chain: A: PDB Molecule:topoisomerase iv subunit a;
PDBTitle: structure of the e. coli parc c-terminal domain

Phyre2
20 |
| c3ku8A_ |

### PDB 3ku8 chain A

Region: 363 - 496
Aligned: 134
Modelled: 134
Confidence: 100.0%
Identity: 100%
PDB header:toxin/isomerase
Chain: A: PDB Molecule:dna gyrase subunit a;
PDBTitle: ccdbvfi:gyra14ec

Phyre2
21 |
22 |
23 |
24 |
25 |
26 |
27 |
28 |
29 |
30 |
31 |
32 |
33 |
34 |
35 |
36 |
37 |
38 |
39 |
40 |
41 |
42 |
43 |
44 |
45 |
46 |
47 |
48 |
49 |
50 |
51 |
52 |
53 |
54 |
55 |
56 |
57 |
58 |
59 |
60 |
61 |
62 |
63 |
64 |
65 |
66 |
67 |
68 |
69 |
70 |
71 |
72 |
73 |
74 |
75 |
76 |
77 |
78 |
79 |
80 |
81 |
82 |
83 |
84 |
85 |
86 |
87 |
88 |
89 |
90 |
91 |
92 |
93 |
94 |
95 |
96 |
97 |
98 |
99 |

Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | c1zvuA_ |
|  | 100.0 | 36 | PDB header:isomerase Chain: A: PDB Molecule:topoisomerase iv subunit a; PDBTitle: structure of the full-length e. coli parc subunit
2 | c2wl2B_ |
|  | 100.0 | 99 | PDB header:isomerase Chain: B: PDB Molecule:dna gyrase subunit a; PDBTitle: crystal structure of n-terminal domain of gyra with the2 antibiotic simocyclinone d8
3 | c2xcsD_ |
|  | 100.0 | 60 | PDB header:isomerase Chain: D: PDB Molecule:dna gyrase subunit b, dna gyrase subunit a; PDBTitle: the 2.1a crystal structure of s. aureus gyrase complex with gsk2994232 and dna
4 | c3ifzA_ |
|  | 100.0 | 52 | PDB header:isomerase Chain: A: PDB Molecule:dna gyrase subunit a; PDBTitle: crystal structure of the first part of the mycobacterium tuberculosis2 dna gyrase reaction core: the breakage and reunion domain at 2.7 a3 resolution
5 | d1ab4a_ |
|  | 100.0 | 98 | Fold:Type II DNA topoisomerase Superfamily:Type II DNA topoisomerase Family:Type II DNA topoisomerase
6 | c2xcqA_ |
|  | 100.0 | 60 | PDB header:isomerase Chain: A: PDB Molecule:dna gyrase subunit b, dna gyrase subunit a; PDBTitle: the 2.98a crystal structure of the catalytic core (b'a'2 region) of staphylococcus aureus dna gyrase
7 | c3ilwA_ |
|  | 100.0 | 51 | PDB header:isomerase Chain: A: PDB Molecule:dna gyrase subunit a; PDBTitle: structure of dna gyrase subunit a n-terminal domain
8 | c2xkjE_ |
|  | 100.0 | 41 | PDB header:isomerase Chain: E: PDB Molecule:topoisomerase iv; PDBTitle: crystal structure of catalytic core of a. baumannii topo iv2 (pare-parc fusion truncate)
9 | c2inrA_ |
|  | 100.0 | 50 | PDB header:isomerase Chain: A: PDB Molecule:dna topoisomerase 4 subunit a; PDBTitle: crystal structure of a 59 kda fragment of topoisomerase iv subunit a2 (grla) from staphylococcus aureus
10 | c2novD_ |
|  | 100.0 | 47 | PDB header:isomerase Chain: D: PDB Molecule:dna topoisomerase 4 subunit a; PDBTitle: breakage-reunion domain of s.pneumoniae topo iv: crystal2 structure of a gram-positive quinolone target
11 | c3qx3B_ |
|  | 100.0 | 25 | PDB header:isomerase/dna/isomerase inhibitor Chain: B: PDB Molecule:dna topoisomerase 2-beta; PDBTitle: human topoisomerase iibeta in complex with dna and etoposide
12 | c1bjtA_ |
|  | 100.0 | 21 | PDB header:topoisomerase Chain: A: PDB Molecule:topoisomerase ii; PDBTitle: topoisomerase ii residues 409-1201
13 | d1bjta_ |
|  | 100.0 | 21 | Fold:Type II DNA topoisomerase Superfamily:Type II DNA topoisomerase Family:Type II DNA topoisomerase
14 | c3l6vA_ |
|  | 100.0 | 59 | PDB header:isomerase Chain: A: PDB Molecule:dna gyrase subunit a; PDBTitle: crystal structure of the xanthomonas campestris gyrase a c-2 terminal domain
15 | d1wp5a_ |
|  | 100.0 | 31 | Fold:6-bladed beta-propeller Superfamily:GyrA/ParC C-terminal domain-like Family:GyrA/ParC C-terminal domain-like
16 | d1suua_ |
|  | 100.0 | 28 | Fold:6-bladed beta-propeller Superfamily:GyrA/ParC C-terminal domain-like Family:GyrA/ParC C-terminal domain-like
17 | c1zi0A_ |
|  | 100.0 | 99 | PDB header:isomerase, dna bindng protein Chain: A: PDB Molecule:dna gyrase subunit a; PDBTitle: a superhelical spiral in escherichia coli dna gyrase a c-2 terminal domain imparts unidirectional supercoiling bias
18 | c3no0B_ |
|  | 100.0 | 24 | PDB header:isomerase Chain: B: PDB Molecule:dna gyrase subunit a; PDBTitle: aquifex aeolicus type iia topoisomerase c-terminal domain
19 | c1zvtA_ |
|  | 100.0 | 18 | PDB header:isomerase Chain: A: PDB Molecule:topoisomerase iv subunit a; PDBTitle: structure of the e. coli parc c-terminal domain
20 | c3ku8A_ |
|  | 100.0 | 100 | PDB header:toxin/isomerase Chain: A: PDB Molecule:dna gyrase subunit a; PDBTitle: ccdbvfi:gyra14ec
21 | d1x75a1 |
| not modelled | 100.0 | 94 | Fold:Type II DNA topoisomerase Superfamily:Type II DNA topoisomerase Family:Type II DNA topoisomerase
22 | c2oajA_ |
| not modelled | 86.9 | 12 | PDB header:endocytosis/exocytosis Chain: A: PDB Molecule:protein sni1; PDBTitle: crystal structure of sro7 from s. cerevisiae
23 | c3dm0A_ |
| not modelled | 73.6 | 15 | PDB header:sugar binding protein,signaling protein Chain: A: PDB Molecule:maltose-binding periplasmic protein fused with PDBTitle: maltose binding protein fusion with rack1 from a. thaliana
24 | c1t3jA_ |
| not modelled | 72.3 | 25 | PDB header:membrane protein Chain: A: PDB Molecule:mitofusin 1; PDBTitle: mitofusin domain hr2 v686m/i708m mutant
25 | c2q6tB_ |
| not modelled | 61.6 | 24 | PDB header:hydrolase Chain: B: PDB Molecule:dnab replication fork helicase; PDBTitle: crystal structure of the thermus aquaticus dnab monomer
26 | c3jroA_ |
| not modelled | 58.2 | 13 | PDB header:transport protein, structural protein Chain: A: PDB Molecule:fusion protein of protein transport protein sec13 PDBTitle: nup84-nup145c-sec13 edge element of the npc lattice
27 | c1c9lA_ |
| not modelled | 56.3 | 13 | PDB header:endocytosis/exocytosis Chain: A: PDB Molecule:clathrin; PDBTitle: peptide-in-groove interactions link target proteins to the2 b-propeller of clathrin
28 | d2g0da1 |
| not modelled | 56.2 | 16 | Fold:alpha/alpha toroid Superfamily:LanC-like Family:LanC-like
29 | d1jwea_ |
| not modelled | 54.0 | 16 | Fold:N-terminal domain of DnaB helicase Superfamily:N-terminal domain of DnaB helicase Family:N-terminal domain of DnaB helicase
30 | c3fokH_ |
| not modelled | 53.6 | 17 | PDB header:structural genomics, unknown function Chain: H: PDB Molecule:uncharacterized protein cgl0159; PDBTitle: crystal structure of cgl0159 from corynebacterium2 glutamicum (brevibacterium flavum). northeast structural3 genomics target cgr115
31 | c3a7pB_ |
| not modelled | 53.5 | 15 | PDB header:protein transport Chain: B: PDB Molecule:autophagy protein 16; PDBTitle: the crystal structure of saccharomyces cerevisiae atg16
32 | c2vyeA_ |
| not modelled | 50.0 | 20 | PDB header:hydrolase Chain: A: PDB Molecule:replicative dna helicase; PDBTitle: crystal structure of the dnac-ssdna complex
33 | c3lssA_ |
| not modelled | 48.2 | 14 | PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase; PDBTitle: trypanosoma brucei seryl-trna synthetase in complex with atp
34 | d2v8qb1 |
| not modelled | 47.9 | 22 | Fold:AMPKBI-like Superfamily:AMPKBI-like Family:AMPKBI-like
35 | c1q1hA_ |
| not modelled | 40.7 | 28 | PDB header:transcription Chain: A: PDB Molecule:transcription factor e; PDBTitle: an extended winged helix domain in general transcription2 factor e/iie alpha
36 | d1q1ha_ |
| not modelled | 40.7 | 28 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Transcription factor E/IIe-alpha, N-terminal domain
37 | c3gndC_ |
| not modelled | 38.8 | 14 | PDB header:lyase Chain: C: PDB Molecule:aldolase lsrf; PDBTitle: crystal structure of e. coli lsrf in complex with ribulose-5-phosphate
38 | d1b79a_ |
| not modelled | 35.4 | 17 | Fold:N-terminal domain of DnaB helicase Superfamily:N-terminal domain of DnaB helicase Family:N-terminal domain of DnaB helicase
39 | c1dpuA_ |
| not modelled | 35.3 | 36 | PDB header:dna binding protein Chain: A: PDB Molecule:replication protein a (rpa32) c-terminal domain; PDBTitle: solution structure of the c-terminal domain of human rpa322 complexed with ung2(73-88)
40 | d1dpua_ |
| not modelled | 35.3 | 36 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:C-terminal domain of RPA32
41 | d2ayua1 |
| not modelled | 34.1 | 15 | Fold:NAP-like Superfamily:NAP-like Family:NAP-like
42 | c2ayuA_ |
| not modelled | 34.1 | 15 | PDB header:chaperone Chain: A: PDB Molecule:nucleosome assembly protein; PDBTitle: the structure of nucleosome assembly protein suggests a mechanism for2 histone binding and shuttling
43 | c2qjhH_ |
| not modelled | 33.8 | 19 | PDB header:lyase Chain: H: PDB Molecule:putative aldolase mj0400; PDBTitle: m. jannaschii adh synthase covalently bound to2 dihydroxyacetone phosphate
44 | c3mkqA_ |
| not modelled | 33.5 | 12 | PDB header:transport protein Chain: A: PDB Molecule:coatomer beta'-subunit; PDBTitle: crystal structure of yeast alpha/betaprime-cop subcomplex of the copi2 vesicular coat
45 | c3a7mA_ |
| not modelled | 29.6 | 13 | PDB header:gene regulation, chaperone Chain: A: PDB Molecule:flagellar protein flit; PDBTitle: structure of flit, the flagellar type iii chaperone for flid
46 | d2qrdb1 |
| not modelled | 29.1 | 15 | Fold:AMPKBI-like Superfamily:AMPKBI-like Family:AMPKBI-like
47 | c2h47F_ |
| not modelled | 28.6 | 10 | PDB header:oxidoreductase/electron transport Chain: F: PDB Molecule:aromatic amine dehydrogenase; PDBTitle: crystal structure of an electron transfer complex between2 aromatic amine dephydrogenase and azurin from alcaligenes3 faecalis (form 1)
48 | c2jesG_ |
| not modelled | 28.4 | 12 | PDB header:viral protein Chain: G: PDB Molecule:portal protein; PDBTitle: portal protein from bacteriophage spp1
49 | c2b5nD_ |
| not modelled | 28.0 | 12 | PDB header:dna binding protein/protein binding Chain: D: PDB Molecule:damage-specific dna binding protein 1; PDBTitle: crystal structure of the ddb1 bpb domain
50 | d2dloa1 |
| not modelled | 27.5 | 71 | Fold:Glucocorticoid receptor-like (DNA-binding domain) Superfamily:Glucocorticoid receptor-like (DNA-binding domain) Family:LIM domain
51 | d1ivsa1 |
| not modelled | 27.3 | 27 | Fold:Long alpha-hairpin Superfamily:tRNA-binding arm Family:Valyl-tRNA synthetase (ValRS) C-terminal domain
52 | c1ce0B_ |
| not modelled | 27.2 | 31 | PDB header:hiv-1 envelope protein Chain: B: PDB Molecule:protein (leucine zipper model h38-p1); PDBTitle: trimerization specificity in hiv-1 gp41: analysis with a2 gcn4 leucine zipper model
53 | c2pqaB_ |
| not modelled | 26.5 | 29 | PDB header:replication Chain: B: PDB Molecule:replication protein a 14 kda subunit; PDBTitle: crystal structure of full-length human rpa 14/32 heterodimer
54 | c3ushB_ |
| not modelled | 26.5 | 23 | PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of the q2s0r5 protein from salinibacter ruber,2 northeast structural genomics consortium target srr207
55 | d1k32a3 |
| not modelled | 24.8 | 10 | Fold:7-bladed beta-propeller Superfamily:Tricorn protease domain 2 Family:Tricorn protease domain 2
56 | d1iwpa_ |
| not modelled | 24.5 | 16 | Fold:TIM beta/alpha-barrel Superfamily:Cobalamin (vitamin B12)-dependent enzymes Family:Diol dehydratase, alpha subunit
57 | d1a06a_ |
| not modelled | 23.9 | 30 | Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit
58 | c2p9mD_ |
| not modelled | 23.7 | 15 | PDB header:structural genomics, unknown function Chain: D: PDB Molecule:hypothetical protein mj0922; PDBTitle: crystal structure of conserved hypothetical protein mj0922 from2 methanocaldococcus jannaschii dsm 2661
59 | d2pi2e1 |
| not modelled | 23.0 | 29 | Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Single strand DNA-binding domain, SSB
60 | c3so4C_ |
| not modelled | 22.3 | 18 | PDB header:transferase Chain: C: PDB Molecule:methionine-adenosyltransferase; PDBTitle: methionine-adenosyltransferase from entamoeba histolytica
61 | c2zezC_ |
| not modelled | 21.9 | 41 | PDB header:hydrolase Chain: C: PDB Molecule:s-layer associated multidomain endoglucanase; PDBTitle: family 16 carbohydrate binding module-2
62 | c3ocmB_ |
| not modelled | 21.0 | 8 | PDB header:membrane protein Chain: B: PDB Molecule:putative membrane protein; PDBTitle: the crystal structure of a domain from a possible membrane protein of2 bordetella parapertussis
63 | c1ztaA_ |
| not modelled | 20.6 | 34 | PDB header:dna-binding motif Chain: A: PDB Molecule:leucine zipper monomer; PDBTitle: the solution structure of a leucine-zipper motif peptide
64 | c3ol2B_ |
| not modelled | 20.4 | 18 | PDB header:signaling protein Chain: B: PDB Molecule:plexin-b1; PDBTitle: receptor-ligand structure of human semaphorin 4d with plexin b1.
65 | d1mlda2 |
| not modelled | 19.4 | 18 | Fold:LDH C-terminal domain-like Superfamily:LDH C-terminal domain-like Family:Lactate & malate dehydrogenases, C-terminal domain
66 | c3izcR_ |
| not modelled | 18.9 | 8 | PDB header:ribosome Chain: R: PDB Molecule:60s ribosomal protein rpl18 (l18e); PDBTitle: localization of the large subunit ribosomal proteins into a 6.1 a2 cryo-em map of saccharomyces cerevisiae translating 80s ribosome
67 | c2dfdD_ |
| not modelled | 18.4 | 21 | PDB header:oxidoreductase Chain: D: PDB Molecule:malate dehydrogenase; PDBTitle: crystal structure of human malate dehydrogenase type 2
68 | d2f2ac1 |
| not modelled | 18.1 | 16 | Fold:Non-globular all-alpha subunits of globular proteins Superfamily:Glu-tRNAGln amidotransferase C subunit Family:Glu-tRNAGln amidotransferase C subunit
69 | c3e5zA_ |
| not modelled | 18.0 | 11 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative gluconolactonase; PDBTitle: x-ray structure of the putative gluconolactonase in protein family2 pf08450. northeast structural genomics consortium target drr130.
70 | c2hpcF_ |
| not modelled | 17.7 | 17 | PDB header:blood clotting Chain: F: PDB Molecule:fibrinogen, gamma polypeptide; PDBTitle: crystal structure of fragment d from human fibrinogen complexed with2 gly-pro-arg-pro-amide.
71 | c1u0iA_ |
| not modelled | 17.6 | 33 | PDB header:de novo protein Chain: A: PDB Molecule:iaal-e3; PDBTitle: iaal-e3/k3 heterodimer
72 | c2lmiA_ |
| not modelled | 17.5 | 13 | PDB header:rna binding protein Chain: A: PDB Molecule:g-rich sequence factor 1; PDBTitle: nmr structure of the protein bc040485 from homo sapiens
73 | c2xzrA_ |
| not modelled | 17.1 | 17 | PDB header:cell adhesion Chain: A: PDB Molecule:immunoglobulin-binding protein eibd; PDBTitle: escherichia coli immunoglobulin-binding protein eibd 391-438 fused2 to gcn4 adaptors
74 | c3czoD_ |
| not modelled | 17.0 | 24 | PDB header:lyase Chain: D: PDB Molecule:histidine ammonia-lyase; PDBTitle: crystal structure of double mutant phenylalanine ammonia-2 lyase from anabaena variabilis
75 | c2a5wC_ |
| not modelled | 16.6 | 19 | PDB header:oxidoreductase Chain: C: PDB Molecule:sulfite reductase, desulfoviridin-type subunit gamma PDBTitle: crystal structure of the oxidized gamma-subunit of the dissimilatory2 sulfite reductase (dsrc) from archaeoglobus fulgidus
76 | c3kpbA_ |
| not modelled | 16.5 | 17 | PDB header:unknown function Chain: A: PDB Molecule:uncharacterized protein mj0100; PDBTitle: crystal structure of the cbs domain pair of protein mj01002 in complex with 5 -methylthioadenosine and s-adenosyl-l-3 methionine.
77 | c1mldA_ |
| not modelled | 16.4 | 18 | PDB header:oxidoreductase(nad(a)-choh(d)) Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: refined structure of mitochondrial malate dehydrogenase2 from porcine heart and the consensus structure for3 dicarboxylic acid oxidoreductases
78 | c2jjmH_ |
| not modelled | 16.1 | 22 | PDB header:transferase Chain: H: PDB Molecule:glycosyl transferase, group 1 family protein; PDBTitle: crystal structure of a family gt4 glycosyltransferase from2 bacillus anthracis orf ba1558.
79 | c2pwzG_ |
| not modelled | 15.8 | 18 | PDB header:oxidoreductase Chain: G: PDB Molecule:malate dehydrogenase; PDBTitle: crystal structure of the apo form of e.coli malate dehydrogenase
80 | c2pfiA_ |
| not modelled | 15.7 | 12 | PDB header:transport protein Chain: A: PDB Molecule:chloride channel protein clc-ka; PDBTitle: crystal structure of the cytoplasmic domain of the human2 chloride channel clc-ka
81 | d1y5ha3 |
| not modelled | 15.6 | 3 | Fold:CBS-domain pair Superfamily:CBS-domain pair Family:CBS-domain pair
82 | c2oszA_ |
| not modelled | 15.4 | 22 | PDB header:structural protein Chain: A: PDB Molecule:nucleoporin p58/p45; PDBTitle: structure of nup58/45 suggests flexible nuclear pore diameter by2 intermolecular sliding
83 | c1yx3A_ |
| not modelled | 15.2 | 25 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein dsrc; PDBTitle: nmr structure of allochromatium vinosum dsrc: northeast2 structural genomics consortium target op4
84 | c2v8kA_ |
| not modelled | 15.0 | 35 | PDB header:lyase Chain: A: PDB Molecule:pectate lyase; PDBTitle: structure of a family 2 pectate lyase in complex with2 trigalacturonic acid
85 | c2r60A_ |
| not modelled | 14.8 | 24 | PDB header:transferase Chain: A: PDB Molecule:glycosyl transferase, group 1; PDBTitle: structure of apo sucrose phosphate synthase (sps) of2 halothermothrix orenii
86 | c3ltjA_ |
| not modelled | 14.6 | 21 | PDB header:protein binding Chain: A: PDB Molecule:alpharep-4; PDBTitle: structure of a new family of artificial alpha helicoidal repeat2 proteins (alpha-rep) based on thermostable heat-like repeats
87 | c3m9bK_ |
| not modelled | 14.5 | 20 | PDB header:chaperone Chain: K: PDB Molecule:proteasome-associated atpase; PDBTitle: crystal structure of the amino terminal coiled coil domain and the2 inter domain of the mycobacterium tuberculosis proteasomal atpase mpa
88 | c3somO_ |
| not modelled | 14.5 | 23 | PDB header:oxidoreductase Chain: O: PDB Molecule:methylmalonic aciduria and homocystinuria type c protein; PDBTitle: crystal structure of human mmachc
89 | c3ue3A_ |
| not modelled | 14.3 | 23 | PDB header:transferase Chain: A: PDB Molecule:septum formation, penicillin binding protein 3, PDBTitle: crystal structure of acinetobacter baumanni pbp3
90 | c3idwA_ |
| not modelled | 13.9 | 20 | PDB header:endocytosis Chain: A: PDB Molecule:actin cytoskeleton-regulatory complex protein sla1; PDBTitle: crystal structure of sla1 homology domain 2
91 | c3l31B_ |
| not modelled | 13.8 | 10 | PDB header:hydrolase Chain: B: PDB Molecule:probable manganase-dependent inorganic PDBTitle: crystal structure of the cbs and drtgg domains of the2 regulatory region of clostridium perfringens3 pyrophosphatase complexed with the inhibitor, amp
92 | c2d4zB_ |
| not modelled | 13.8 | 21 | PDB header:transport protein Chain: B: PDB Molecule:chloride channel protein; PDBTitle: crystal structure of the cytoplasmic domain of the chloride channel2 clc-0
93 | c2qh1B_ |
| not modelled | 13.7 | 18 | PDB header:unknown function Chain: B: PDB Molecule:hypothetical protein ta0289; PDBTitle: structure of ta289, a cbs-rubredoxin-like protein, in its fe+2-bound2 state
94 | d1rp3a2 |
| not modelled | 13.4 | 13 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:Sigma3 and sigma4 domains of RNA polymerase sigma factors Family:Sigma4 domain
95 | d1o50a3 |
| not modelled | 13.2 | 15 | Fold:CBS-domain pair Superfamily:CBS-domain pair Family:CBS-domain pair
96 | d1wi9a_ |
| not modelled | 12.9 | 19 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:PCI domain (PINT motif)
97 | c3kfuJ_ |
| not modelled | 12.9 | 26 | PDB header:ligase/rna Chain: J: PDB Molecule:glutamyl-trna(gln) amidotransferase subunit c; PDBTitle: crystal structure of the transamidosome
98 | d1n0ua3 |
| not modelled | 12.8 | 26 | Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:Translational machinery components
99 | d2ca1a1 |
| not modelled | 12.7 | 21 | Fold:Nucleocapsid protein dimerization domain Superfamily:Nucleocapsid protein dimerization domain Family:Coronavirus nucleocapsid protein

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0