Phyre 2 Results for P0A7F3

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Email | l.a.kelley@imperial.ac.uk
Description | P0A7F3
Date | Thu Jan 5 11:05:33 GMT 2012
Unique Job ID | 8906af9600ed0ab5

Summary |

Top model
Image coloured by rainbow N → C terminus
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Model (left) based on template c2h3eB_
Top template information
PDB header:transferase Chain: B: PDB Molecule:aspartate carbamoyltransferase regulatory chain; PDBTitle: structure of wild-type e. coli aspartate transcarbamoylase in the2 presence of n-phosphonacetyl-l-isoasparagine at 2.3a resolution
Confidence and coverage
Confidence: | 100.0% | Coverage: | 95%
145 residues ( 95% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | T | H | D | N | K | L | Q | V | E | A | I | K | R | G | T | V | I | D | H | I | P | A | Q | I | G | F | K | L | L | S | L | F | K | L | T | E | T | D | Q | R | I | T | I | G | L | N | L | P | S | G | E | M | G | R | K | D | L | I | K
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? |  |  |  | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? |  | ? | ? | ? |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | I | E | N | T | F | L | S | E | D | Q | V | D | Q | L | A | L | Y | A | P | Q | A | T | V | N | R | I | D | N | Y | E | V | V | G | K | S | R | P | S | L | P | E | R | I | D | N | V | L | V | C | P | N | S | N | C | I | S | H | A | E | P
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | .
Sequence |  | V | S | S | S | F | A | V | R | K | R | A | N | D | I | A | L | K | C | K | Y | C | E | K | E | F | S | H | N | V | V | L | A | N
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| c2h3eB_ |

### PDB 2h3e chain B

Region: 9 - 153
Aligned: 145
Modelled: 145
Confidence: 100.0%
Identity: 100%
PDB header:transferase
Chain: B: PDB Molecule:aspartate carbamoyltransferase regulatory chain;
PDBTitle: structure of wild-type e. coli aspartate transcarbamoylase in the2 presence of n-phosphonacetyl-l-isoasparagine at 2.3a resolution

Phyre2
2 |
| c1pg5B_ |

### PDB 1pg5 chain B

Region: 8 - 153
Aligned: 145
Modelled: 146
Confidence: 100.0%
Identity: 34%
PDB header:transferase
Chain: B: PDB Molecule:aspartate carbamoyltransferase regulatory chain;
PDBTitle: crystal structure of the unligated (t-state) aspartate2 transcarbamoylase from the extremely thermophilic archaeon sulfolobus3 acidocaldarius

Phyre2
3 |
| c2ywwA_ |

### PDB 2yww chain A

Region: 8 - 150
Aligned: 141
Modelled: 141
Confidence: 100.0%
Identity: 35%
PDB header:metal binding protein
Chain: A: PDB Molecule:aspartate carbamoyltransferase regulatory chain;
PDBTitle: crystal structure of aspartate carbamoyltransferase2 regulatory chain from methanocaldococcus jannaschii

Phyre2
4 |
| c2be7E_ |

### PDB 2be7 chain E

Region: 14 - 151
Aligned: 128
Modelled: 138
Confidence: 100.0%
Identity: 57%
PDB header:transferase
Chain: E: PDB Molecule:aspartate carbamoyltransferase regulatory chain;
PDBTitle: crystal structure of the unliganded (t-state) aspartate2 transcarbamoylase of the psychrophilic bacterium moritella profunda

Phyre2
5 |
| d2fzcb1 |

### PDB 2fzc chain B domain 1

Region: 2 - 100
Aligned: 99
Modelled: 99
Confidence: 100.0%
Identity: 100%
Fold: Ferredoxin-like
Superfamily: Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain
Family: Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain

Phyre2
6 |
| d2atcb1 |

### PDB 2atc chain B domain 1

Region: 1 - 100
Aligned: 100
Modelled: 100
Confidence: 100.0%
Identity: 88%
Fold: Ferredoxin-like
Superfamily: Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain
Family: Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain

Phyre2
7 |
| d1pg5b1 |

### PDB 1pg5 chain B domain 1

Region: 8 - 100
Aligned: 92
Modelled: 93
Confidence: 100.0%
Identity: 42%
Fold: Ferredoxin-like
Superfamily: Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain
Family: Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain

Phyre2
8 |
| d2fzcb2 |

### PDB 2fzc chain B domain 2

Region: 101 - 153
Aligned: 53
Modelled: 53
Confidence: 99.8%
Identity: 100%
Fold: Rubredoxin-like
Superfamily: Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain
Family: Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain

Phyre2
9 |
| d2atcb2 |

### PDB 2atc chain B domain 2

Region: 101 - 153
Aligned: 52
Modelled: 53
Confidence: 99.7%
Identity: 90%
Fold: Rubredoxin-like
Superfamily: Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain
Family: Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain

Phyre2
10 |
| d1pg5b2 |

### PDB 1pg5 chain B domain 2

Region: 101 - 153
Aligned: 52
Modelled: 53
Confidence: 99.7%
Identity: 23%
Fold: Rubredoxin-like
Superfamily: Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain
Family: Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain

Phyre2
11 |
| c1xrzA_ |

### PDB 1xrz chain A

Region: 136 - 143
Aligned: 8
Modelled: 8
Confidence: 51.4%
Identity: 50%
PDB header:transcription
Chain: A: PDB Molecule:zinc finger y-chromosomal protein;
PDBTitle: nmr structure of a zinc finger with cyclohexanylalanine2 substituted for the central aromatic residue

Phyre2
12 |
| c7znfA_ |

### PDB 7znf chain A

Region: 136 - 148
Aligned: 13
Modelled: 13
Confidence: 42.9%
Identity: 46%
PDB header:zinc finger dna binding domain
Chain: A: PDB Molecule:zinc finger;
PDBTitle: alternating zinc fingers in the human male associated2 protein zfy: 2d nmr structure of an even finger and3 implications for "jumping-linker" dna recognition

Phyre2
13 |
| d7znfa_ |

### PDB 7znf chain A

Region: 136 - 148
Aligned: 13
Modelled: 13
Confidence: 42.9%
Identity: 46%
Fold: beta-beta-alpha zinc fingers
Superfamily: beta-beta-alpha zinc fingers
Family: Classic zinc finger, C2H2

Phyre2
14 |
| d1pvma3 |

### PDB 1pvm chain A domain 3

Region: 106 - 114
Aligned: 9
Modelled: 9
Confidence: 41.1%
Identity: 44%
Fold: Rubredoxin-like
Superfamily: Hypothetical protein Ta0289 C-terminal domain
Family: Hypothetical protein Ta0289 C-terminal domain

Phyre2
15 |
| c1dgsB_ |

### PDB 1dgs chain B

Region: 77 - 114
Aligned: 38
Modelled: 38
Confidence: 39.2%
Identity: 26%
PDB header:ligase
Chain: B: PDB Molecule:dna ligase;
PDBTitle: crystal structure of nad+-dependent dna ligase from t.2 filiformis

Phyre2
16 |
| c2elpA_ |

### PDB 2elp chain A

Region: 131 - 149
Aligned: 19
Modelled: 19
Confidence: 38.7%
Identity: 37%
PDB header:transcription
Chain: A: PDB Molecule:zinc finger protein 406;
PDBTitle: solution structure of the 13th c2h2 zinc finger of human2 zinc finger protein 406

Phyre2
17 |
| d1vq0a2 |

### PDB 1vq0 chain A domain 2

Region: 132 - 148
Aligned: 17
Modelled: 17
Confidence: 38.3%
Identity: 18%
Fold: HSP33 redox switch-like
Superfamily: HSP33 redox switch-like
Family: HSP33 redox switch-like

Phyre2
18 |
| c2l8eA_ |

### PDB 2l8e chain A

Region: 130 - 144
Aligned: 15
Modelled: 15
Confidence: 37.6%
Identity: 40%
PDB header:dna binding protein
Chain: A: PDB Molecule:polyhomeotic-like protein 1;
PDBTitle: solution nmr structure of fcs domain of human polyhomeotic homolog 12 (hph1)

Phyre2
19 |
| c1rikA_ |

### PDB 1rik chain A

Region: 135 - 149
Aligned: 15
Modelled: 15
Confidence: 37.4%
Identity: 27%
PDB header:de novo protein
Chain: A: PDB Molecule:e6apc1 peptide;
PDBTitle: e6-binding zinc finger (e6apc1)

Phyre2
20 |
| c5znfA_ |

### PDB 5znf chain A

Region: 136 - 142
Aligned: 7
Modelled: 7
Confidence: 37.3%
Identity: 57%
PDB header:zinc finger dna binding domain
Chain: A: PDB Molecule:zinc finger;
PDBTitle: alternating zinc fingers in the human male associated2 protein zfy: 2d nmr structure of an even finger and3 implications for "jumping-linker" dna recognition

Phyre2
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Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | c2h3eB_ |
|  | 100.0 | 100 | PDB header:transferase Chain: B: PDB Molecule:aspartate carbamoyltransferase regulatory chain; PDBTitle: structure of wild-type e. coli aspartate transcarbamoylase in the2 presence of n-phosphonacetyl-l-isoasparagine at 2.3a resolution
2 | c1pg5B_ |
|  | 100.0 | 34 | PDB header:transferase Chain: B: PDB Molecule:aspartate carbamoyltransferase regulatory chain; PDBTitle: crystal structure of the unligated (t-state) aspartate2 transcarbamoylase from the extremely thermophilic archaeon sulfolobus3 acidocaldarius
3 | c2ywwA_ |
|  | 100.0 | 35 | PDB header:metal binding protein Chain: A: PDB Molecule:aspartate carbamoyltransferase regulatory chain; PDBTitle: crystal structure of aspartate carbamoyltransferase2 regulatory chain from methanocaldococcus jannaschii
4 | c2be7E_ |
|  | 100.0 | 57 | PDB header:transferase Chain: E: PDB Molecule:aspartate carbamoyltransferase regulatory chain; PDBTitle: crystal structure of the unliganded (t-state) aspartate2 transcarbamoylase of the psychrophilic bacterium moritella profunda
5 | d2fzcb1 |
|  | 100.0 | 100 | Fold:Ferredoxin-like Superfamily:Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain Family:Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain
6 | d2atcb1 |
|  | 100.0 | 88 | Fold:Ferredoxin-like Superfamily:Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain Family:Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain
7 | d1pg5b1 |
|  | 100.0 | 42 | Fold:Ferredoxin-like Superfamily:Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain Family:Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain
8 | d2fzcb2 |
|  | 99.8 | 100 | Fold:Rubredoxin-like Superfamily:Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain Family:Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain
9 | d2atcb2 |
|  | 99.7 | 90 | Fold:Rubredoxin-like Superfamily:Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain Family:Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain
10 | d1pg5b2 |
|  | 99.7 | 23 | Fold:Rubredoxin-like Superfamily:Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain Family:Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain
11 | c1xrzA_ |
|  | 51.4 | 50 | PDB header:transcription Chain: A: PDB Molecule:zinc finger y-chromosomal protein; PDBTitle: nmr structure of a zinc finger with cyclohexanylalanine2 substituted for the central aromatic residue
12 | c7znfA_ |
|  | 42.9 | 46 | PDB header:zinc finger dna binding domain Chain: A: PDB Molecule:zinc finger; PDBTitle: alternating zinc fingers in the human male associated2 protein zfy: 2d nmr structure of an even finger and3 implications for "jumping-linker" dna recognition
13 | d7znfa_ |
|  | 42.9 | 46 | Fold:beta-beta-alpha zinc fingers Superfamily:beta-beta-alpha zinc fingers Family:Classic zinc finger, C2H2
14 | d1pvma3 |
|  | 41.1 | 44 | Fold:Rubredoxin-like Superfamily:Hypothetical protein Ta0289 C-terminal domain Family:Hypothetical protein Ta0289 C-terminal domain
15 | c1dgsB_ |
|  | 39.2 | 26 | PDB header:ligase Chain: B: PDB Molecule:dna ligase; PDBTitle: crystal structure of nad+-dependent dna ligase from t.2 filiformis
16 | c2elpA_ |
|  | 38.7 | 37 | PDB header:transcription Chain: A: PDB Molecule:zinc finger protein 406; PDBTitle: solution structure of the 13th c2h2 zinc finger of human2 zinc finger protein 406
17 | d1vq0a2 |
|  | 38.3 | 18 | Fold:HSP33 redox switch-like Superfamily:HSP33 redox switch-like Family:HSP33 redox switch-like
18 | c2l8eA_ |
|  | 37.6 | 40 | PDB header:dna binding protein Chain: A: PDB Molecule:polyhomeotic-like protein 1; PDBTitle: solution nmr structure of fcs domain of human polyhomeotic homolog 12 (hph1)
19 | c1rikA_ |
|  | 37.4 | 27 | PDB header:de novo protein Chain: A: PDB Molecule:e6apc1 peptide; PDBTitle: e6-binding zinc finger (e6apc1)
20 | c5znfA_ |
|  | 37.3 | 57 | PDB header:zinc finger dna binding domain Chain: A: PDB Molecule:zinc finger; PDBTitle: alternating zinc fingers in the human male associated2 protein zfy: 2d nmr structure of an even finger and3 implications for "jumping-linker" dna recognition
21 | d1xjha_ |
| not modelled | 35.6 | 29 | Fold:HSP33 redox switch-like Superfamily:HSP33 redox switch-like Family:HSP33 redox switch-like
22 | c2jvmA_ |
| not modelled | 35.2 | 13 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution nmr structure of rhodobacter sphaeroides protein2 rhos4_26430. northeast structural genomics consortium3 target rhr95
23 | c1vzyA_ |
| not modelled | 34.9 | 12 | PDB header:chaperone Chain: A: PDB Molecule:33 kda chaperonin; PDBTitle: crystal structure of the bacillus subtilis hsp33
24 | d1vzya2 |
| not modelled | 34.1 | 12 | Fold:HSP33 redox switch-like Superfamily:HSP33 redox switch-like Family:HSP33 redox switch-like
25 | c3siqF_ |
| not modelled | 33.4 | 17 | PDB header:ligase Chain: F: PDB Molecule:apoptosis 1 inhibitor; PDBTitle: crystal structure of autoinhibited diap1-bir1 domain
26 | c2jrrA_ |
| not modelled | 32.7 | 13 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution nmr structure of q5lls5 from silicibacter2 pomeroyi. northeast structural genomics consortium target3 sir90
27 | c1vq0A_ |
| not modelled | 32.1 | 17 | PDB header:chaperone Chain: A: PDB Molecule:33 kda chaperonin; PDBTitle: crystal structure of 33 kda chaperonin (heat shock protein 33 homolog)2 (hsp33) (tm1394) from thermotoga maritima at 2.20 a resolution
28 | c1klsA_ |
| not modelled | 29.8 | 57 | PDB header:transcription Chain: A: PDB Molecule:zinc finger y-chromosomal protein; PDBTitle: nmr structure of the zfy-6t[y10l] zinc finger
29 | c1klrA_ |
| not modelled | 29.6 | 57 | PDB header:transcription Chain: A: PDB Molecule:zinc finger y-chromosomal protein; PDBTitle: nmr structure of the zfy-6t[y10f] zinc finger
30 | d1klra_ |
| not modelled | 29.6 | 57 | Fold:beta-beta-alpha zinc fingers Superfamily:beta-beta-alpha zinc fingers Family:Classic zinc finger, C2H2
31 | d1njqa_ |
| not modelled | 28.0 | 29 | Fold:beta-beta-alpha zinc fingers Superfamily:beta-beta-alpha zinc fingers Family:Plant C2H2 finger (QALGGH zinc finger)
32 | c2elvA_ |
| not modelled | 27.5 | 22 | PDB header:transcription Chain: A: PDB Molecule:zinc finger protein 406; PDBTitle: solution structure of the 6th c2h2 zinc finger of human2 zinc finger protein 406
33 | d2cota1 |
| not modelled | 27.0 | 42 | Fold:beta-beta-alpha zinc fingers Superfamily:beta-beta-alpha zinc fingers Family:Classic zinc finger, C2H2
34 | d1a1ia2 |
| not modelled | 26.9 | 24 | Fold:beta-beta-alpha zinc fingers Superfamily:beta-beta-alpha zinc fingers Family:Classic zinc finger, C2H2
35 | d1llmc2 |
| not modelled | 26.6 | 18 | Fold:beta-beta-alpha zinc fingers Superfamily:beta-beta-alpha zinc fingers Family:Classic zinc finger, C2H2
36 | c2eltA_ |
| not modelled | 25.3 | 19 | PDB header:transcription Chain: A: PDB Molecule:zinc finger protein 406; PDBTitle: solution structure of the 3rd c2h2 zinc finger of human2 zinc finger protein 406
37 | d2ct1a2 |
| not modelled | 25.2 | 20 | Fold:beta-beta-alpha zinc fingers Superfamily:beta-beta-alpha zinc fingers Family:Classic zinc finger, C2H2
38 | c1arfA_ |
| not modelled | 25.1 | 21 | PDB header:transcription regulation Chain: A: PDB Molecule:yeast transcription factor adr1; PDBTitle: structures of dna-binding mutant zinc finger domains:2 implications for dna binding
39 | c2jz8A_ |
| not modelled | 24.2 | 14 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein bh09830; PDBTitle: solution nmr structure of bh09830 from bartonella henselae2 modeled with one zn+2 bound. northeast structural genomics3 consortium target bnr55
40 | d1ncsa_ |
| not modelled | 24.1 | 28 | Fold:beta-beta-alpha zinc fingers Superfamily:beta-beta-alpha zinc fingers Family:Classic zinc finger, C2H2
41 | c1meyG_ |
| not modelled | 23.9 | 38 | PDB header:transferase/dna Chain: G: PDB Molecule:consensus zinc finger; PDBTitle: crystal structure of a designed zinc finger protein bound2 to dna
42 | c2eprA_ |
| not modelled | 22.8 | 22 | PDB header:transcription Chain: A: PDB Molecule:poz-, at hook-, and zinc finger-containing PDBTitle: solution structure of the secound zinc finger domain of2 zinc finger protein 278
43 | c3t6pA_ |
| not modelled | 22.6 | 25 | PDB header:apoptosis Chain: A: PDB Molecule:baculoviral iap repeat-containing protein 2; PDBTitle: iap antagonist-induced conformational change in ciap1 promotes e32 ligase activation via dimerization
44 | d1u85a1 |
| not modelled | 22.3 | 36 | Fold:beta-beta-alpha zinc fingers Superfamily:beta-beta-alpha zinc fingers Family:Classic zinc finger, C2H2
45 | c2elqA_ |
| not modelled | 21.7 | 25 | PDB header:transcription Chain: A: PDB Molecule:zinc finger protein 406; PDBTitle: solution structure of the 14th c2h2 zinc finger of human2 zinc finger protein 406
46 | c2drpD_ |
| not modelled | 21.4 | 20 | PDB header:transcription/dna Chain: D: PDB Molecule:protein (tramtrack dna-binding domain); PDBTitle: the crystal structure of a two zinc-finger peptide reveals2 an extension to the rules for zinc-finger/dna recognition
47 | d1m4ma_ |
| not modelled | 21.2 | 22 | Fold:Inhibitor of apoptosis (IAP) repeat Superfamily:Inhibitor of apoptosis (IAP) repeat Family:Inhibitor of apoptosis (IAP) repeat
48 | d1tfqa_ |
| not modelled | 21.1 | 19 | Fold:Inhibitor of apoptosis (IAP) repeat Superfamily:Inhibitor of apoptosis (IAP) repeat Family:Inhibitor of apoptosis (IAP) repeat
49 | c2el5A_ |
| not modelled | 21.0 | 33 | PDB header:transcription Chain: A: PDB Molecule:zinc finger protein 268; PDBTitle: solution structure of the 18th zf-c2h2 domain from human2 zinc finger protein 268
50 | c3m0aD_ |
| not modelled | 20.5 | 19 | PDB header:signaling protein Chain: D: PDB Molecule:baculoviral iap repeat-containing protein 3; PDBTitle: crystal structure of traf2:ciap2 complex
51 | d1i3oe_ |
| not modelled | 20.3 | 10 | Fold:Inhibitor of apoptosis (IAP) repeat Superfamily:Inhibitor of apoptosis (IAP) repeat Family:Inhibitor of apoptosis (IAP) repeat
52 | d2raxa1 |
| not modelled | 20.1 | 19 | Fold:Inhibitor of apoptosis (IAP) repeat Superfamily:Inhibitor of apoptosis (IAP) repeat Family:Inhibitor of apoptosis (IAP) repeat
53 | d1xb0a_ |
| not modelled | 20.1 | 9 | Fold:Inhibitor of apoptosis (IAP) repeat Superfamily:Inhibitor of apoptosis (IAP) repeat Family:Inhibitor of apoptosis (IAP) repeat
54 | d1srka_ |
| not modelled | 20.0 | 18 | Fold:beta-beta-alpha zinc fingers Superfamily:beta-beta-alpha zinc fingers Family:Classic zinc finger, C2H2
55 | d2dkta1 |
| not modelled | 20.0 | 23 | Fold:CHY zinc finger-like Superfamily:CHY zinc finger-like Family:CHY zinc finger
56 | d2vsla1 |
| not modelled | 19.7 | 12 | Fold:Inhibitor of apoptosis (IAP) repeat Superfamily:Inhibitor of apoptosis (IAP) repeat Family:Inhibitor of apoptosis (IAP) repeat
57 | d1a1ia3 |
| not modelled | 19.3 | 18 | Fold:beta-beta-alpha zinc fingers Superfamily:beta-beta-alpha zinc fingers Family:Classic zinc finger, C2H2
58 | d1se0a_ |
| not modelled | 19.3 | 19 | Fold:Inhibitor of apoptosis (IAP) repeat Superfamily:Inhibitor of apoptosis (IAP) repeat Family:Inhibitor of apoptosis (IAP) repeat
59 | d1q4qa_ |
| not modelled | 19.0 | 13 | Fold:Inhibitor of apoptosis (IAP) repeat Superfamily:Inhibitor of apoptosis (IAP) repeat Family:Inhibitor of apoptosis (IAP) repeat
60 | d1m4ka2 |
| not modelled | 18.9 | 12 | Fold:Immunoglobulin-like beta-sandwich Superfamily:Immunoglobulin Family:I set domains
61 | d2i3ha1 |
| not modelled | 18.8 | 14 | Fold:Inhibitor of apoptosis (IAP) repeat Superfamily:Inhibitor of apoptosis (IAP) repeat Family:Inhibitor of apoptosis (IAP) repeat
62 | d1dgsa1 |
| not modelled | 18.8 | 56 | Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:NAD+-dependent DNA ligase, domain 3
63 | d1tf3a2 |
| not modelled | 18.4 | 43 | Fold:beta-beta-alpha zinc fingers Superfamily:beta-beta-alpha zinc fingers Family:Classic zinc finger, C2H2
64 | d3d9ta1 |
| not modelled | 18.4 | 29 | Fold:Inhibitor of apoptosis (IAP) repeat Superfamily:Inhibitor of apoptosis (IAP) repeat Family:Inhibitor of apoptosis (IAP) repeat
65 | d2epsa1 |
| not modelled | 18.1 | 42 | Fold:beta-beta-alpha zinc fingers Superfamily:beta-beta-alpha zinc fingers Family:Classic zinc finger, C2H2
66 | d1xb0b_ |
| not modelled | 18.1 | 14 | Fold:Inhibitor of apoptosis (IAP) repeat Superfamily:Inhibitor of apoptosis (IAP) repeat Family:Inhibitor of apoptosis (IAP) repeat
67 | d2epra1 |
| not modelled | 18.1 | 36 | Fold:beta-beta-alpha zinc fingers Superfamily:beta-beta-alpha zinc fingers Family:Classic zinc finger, C2H2
68 | c1v9pB_ |
| not modelled | 17.9 | 24 | PDB header:ligase Chain: B: PDB Molecule:dna ligase; PDBTitle: crystal structure of nad+-dependent dna ligase
69 | d1x6ha2 |
| not modelled | 17.4 | 26 | Fold:beta-beta-alpha zinc fingers Superfamily:beta-beta-alpha zinc fingers Family:Classic zinc finger, C2H2
70 | c2poiA_ |
| not modelled | 16.9 | 13 | PDB header:signaling protein/apoptosis Chain: A: PDB Molecule:baculoviral iap repeat-containing protein 4; PDBTitle: crystal structure of xiap bir1 domain (i222 form)
71 | c2elsA_ |
| not modelled | 16.9 | 28 | PDB header:transcription Chain: A: PDB Molecule:zinc finger protein 406; PDBTitle: solution structure of the 2nd c2h2 zinc finger of human2 zinc finger protein 406
72 | d1g73d_ |
| not modelled | 16.8 | 19 | Fold:Inhibitor of apoptosis (IAP) repeat Superfamily:Inhibitor of apoptosis (IAP) repeat Family:Inhibitor of apoptosis (IAP) repeat
73 | d1jd5a_ |
| not modelled | 16.6 | 14 | Fold:Inhibitor of apoptosis (IAP) repeat Superfamily:Inhibitor of apoptosis (IAP) repeat Family:Inhibitor of apoptosis (IAP) repeat
74 | c1va3A_ |
| not modelled | 16.5 | 29 | PDB header:transcription Chain: A: PDB Molecule:transcription factor sp1; PDBTitle: solution structure of transcription factor sp1 dna binding2 domain (zinc finger 3)
75 | d2vrda1 |
| not modelled | 16.5 | 27 | Fold:beta-beta-alpha zinc fingers Superfamily:beta-beta-alpha zinc fingers Family:HkH motif-containing C2H2 finger
76 | d1oxna_ |
| not modelled | 16.4 | 14 | Fold:Inhibitor of apoptosis (IAP) repeat Superfamily:Inhibitor of apoptosis (IAP) repeat Family:Inhibitor of apoptosis (IAP) repeat
77 | d1x6ea2 |
| not modelled | 16.2 | 50 | Fold:beta-beta-alpha zinc fingers Superfamily:beta-beta-alpha zinc fingers Family:Classic zinc finger, C2H2
78 | d1vd4a_ |
| not modelled | 16.1 | 14 | Fold:Rubredoxin-like Superfamily:Zinc beta-ribbon Family:Transcriptional factor domain
79 | c1rimA_ |
| not modelled | 16.0 | 27 | PDB header:de novo protein Chain: A: PDB Molecule:e6apc2 peptide; PDBTitle: e6-binding zinc finger (e6apc2)
80 | c2yu5A_ |
| not modelled | 15.7 | 31 | PDB header:rna binding protein Chain: A: PDB Molecule:zinc finger protein 473; PDBTitle: solution structure of the zf-c2h2 domain (669-699aa) in2 zinc finger protein 473
81 | c2eoxA_ |
| not modelled | 15.7 | 21 | PDB header:transcription Chain: A: PDB Molecule:zinc finger protein 473; PDBTitle: solution structure of the c2h2 type zinc finger (region 315-2 345) of human zinc finger protein 473
82 | d1xf7a_ |
| not modelled | 15.7 | 45 | Fold:beta-beta-alpha zinc fingers Superfamily:beta-beta-alpha zinc fingers Family:Classic zinc finger, C2H2
83 | c1xf7A_ |
| not modelled | 15.7 | 45 | PDB header:transcription Chain: A: PDB Molecule:wilms' tumor protein; PDBTitle: high resolution nmr structure of the wilms' tumor2 suppressor protein (wt1) finger 3
84 | d2qfaa1 |
| not modelled | 15.6 | 19 | Fold:Inhibitor of apoptosis (IAP) repeat Superfamily:Inhibitor of apoptosis (IAP) repeat Family:Inhibitor of apoptosis (IAP) repeat
85 | c2epcA_ |
| not modelled | 15.6 | 21 | PDB header:transcription Chain: A: PDB Molecule:zinc finger protein 32; PDBTitle: solution structure of zinc finger domain 7 in zinc finger2 protein 32
86 | d1nkra2 |
| not modelled | 15.6 | 12 | Fold:Immunoglobulin-like beta-sandwich Superfamily:Immunoglobulin Family:I set domains
87 | c2eifA_ |
| not modelled | 15.3 | 13 | PDB header:gene regulation Chain: A: PDB Molecule:protein (eukaryotic translation initiation factor 5a); PDBTitle: eukaryotic translation initiation factor 5a from methanococcus2 jannaschii
88 | d2drpa1 |
| not modelled | 15.3 | 20 | Fold:beta-beta-alpha zinc fingers Superfamily:beta-beta-alpha zinc fingers Family:Classic zinc finger, C2H2
89 | c2epuA_ |
| not modelled | 15.1 | 33 | PDB header:transcription Chain: A: PDB Molecule:zinc finger protein 32; PDBTitle: solution structure of the secound c2h2 type zinc finger2 domain of zinc finger protein 32
90 | c1oy7C_ |
| not modelled | 14.9 | 14 | PDB header:apoptosis/peptide Chain: C: PDB Molecule:baculoviral iap repeat-containing protein 7; PDBTitle: structure and function analysis of peptide antagonists of melanoma2 inhibitor of apoptosis (ml-iap)
91 | c2en3A_ |
| not modelled | 14.6 | 25 | PDB header:transcription Chain: A: PDB Molecule:zinc finger protein 95 homolog; PDBTitle: solution structure of the c2h2 type zinc finger (region 796-2 828) of human zinc finger protein 95 homolog
92 | c2vm5A_ |
| not modelled | 14.5 | 14 | PDB header:apoptosis Chain: A: PDB Molecule:baculoviral iap repeat-containing protein 1; PDBTitle: human bir2 domain of baculoviral inhibitor of apoptosis2 repeat-containing 1 (birc1)
93 | d1ueba1 |
| not modelled | 14.2 | 10 | Fold:SH3-like barrel Superfamily:Translation proteins SH3-like domain Family:eIF5a N-terminal domain-like
94 | c3m1cA_ |
| not modelled | 14.0 | 22 | PDB header:viral protein Chain: A: PDB Molecule:envelope glycoprotein h; PDBTitle: crystal structure of the conserved herpesvirus fusion regulator2 complex gh-gl
95 | d1ubdc3 |
| not modelled | 14.0 | 42 | Fold:beta-beta-alpha zinc fingers Superfamily:beta-beta-alpha zinc fingers Family:Classic zinc finger, C2H2
96 | d1sp1a_ |
| not modelled | 13.9 | 29 | Fold:beta-beta-alpha zinc fingers Superfamily:beta-beta-alpha zinc fingers Family:Classic zinc finger, C2H2
97 | c1sp1A_ |
| not modelled | 13.9 | 29 | PDB header:zinc finger Chain: A: PDB Molecule:sp1f3; PDBTitle: nmr structure of a zinc finger domain from transcription2 factor sp1f3, minimized average structure
98 | d2dl2a1 |
| not modelled | 13.2 | 12 | Fold:Immunoglobulin-like beta-sandwich Superfamily:Immunoglobulin Family:I set domains
99 | c2en8A_ |
| not modelled | 13.1 | 20 | PDB header:transcription Chain: A: PDB Molecule:zinc finger protein 224; PDBTitle: solution structure of the c2h2 type zinc finger (region 171-2 203) of human zinc finger protein 224

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0