Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	F	N	T	I	I	D	W	N	S	C	T	A	E	Q	Q	R	Q	L	L	M	R	P	A	I	S	A	S	E	S	I	T	R	T	V	N	D	I	L	D	N	V	K	A	R	G	D	E	A	L	R	E	Y	S	A	K	F	D	K
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?						?											?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		T	T	V	T	A	L	K	V	S	A	E	E	I	A	A	A	S	E	R	L	S	D	E	L	K	Q	A	M	A	V	A	V	K	N	I	E	T	F	H	T	A	Q	K	L	P	P	V	D	V	E	T	Q	P	G	V	R	C	Q	Q	V
Secondary structure
SS confidence
Disorder				?				?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		T	R	P	V	A	S	V	G	L	Y	I	P	G	G	S	A	P	L	F	S	T	V	L	M	L	A	T	P	A	S	I	A	G	C	K	K	V	V	L	C	S	P	P	P	I	A	D	E	I	L	Y	A	A	Q	L	C	G	V	Q	D
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		V	F	N	V	G	G	A	Q	A	I	A	A	L	A	F	G	T	E	S	V	P	K	V	D	K	I	F	G	P	G	N	A	F	V	T	E	A	K	R	Q	V	S	Q	R	L	D	G	A	A	I	D	M	P	A	G	P	S	E	V	L
Secondary structure
SS confidence
Disorder																																														?				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		V	I	A	D	S	G	A	T	P	D	F	V	A	S	D	L	L	S	Q	A	E	H	G	P	D	S	Q	V	I	L	L	T	P	A	A	D	M	A	R	R	V	A	E	A	V	E	R	Q	L	A	E	L	P	R	A	E	T	A	R	Q
Secondary structure
SS confidence
Disorder																																																							?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		A	L	N	A	S	R	L	I	V	T	K	D	L	A	Q	C	V	E	I	S	N	Q	Y	G	P	E	H	L	I	I	Q	T	R	N	A	R	E	L	V	D	S	I	T	S	A	G	S	V	F	L	G	D	W	S	P	E	S	A	G	D
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		Y	A	S	G	T	N	H	V	L	P	T	Y	G	Y	T	A	T	C	S	S	L	G	L	A	D	F	Q	K	R	M	T	V	Q	E	L	S	K	E	G	F	S	A	L	A	S	T	I	E	T	L	A	A	A	E	R	L	T	A	H	K
Secondary structure
SS confidence
Disorder																	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.
Sequence		N	A	V	T	L	R	V	N	A	L	K	E	Q	A
Secondary structure
SS confidence
Disorder												?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1k75 chain A Region: 4 - 434 Aligned: 431 Modelled: 431 Confidence: 100.0% Identity: 99% Fold: ALDH-like Superfamily: ALDH-like Family: L-histidinol dehydrogenase HisD Phyre2 PDB 2w8q chain A Region: 9 - 395 Aligned: 341 Modelled: 351 Confidence: 99.1% Identity: 16% PDB header:oxidoreductase Chain: A: PDB Molecule:succinate-semialdehyde dehydrogenase, PDBTitle: the crystal structure of human ssadh in complex with ssa. Phyre2 PDB 1ky8 chain A Region: 9 - 393 Aligned: 334 Modelled: 349 Confidence: 99.0% Identity: 18% Fold: ALDH-like Superfamily: ALDH-like Family: ALDH-like Phyre2 PDB 1euh chain A Region: 9 - 394 Aligned: 343 Modelled: 357 Confidence: 98.9% Identity: 14% Fold: ALDH-like Superfamily: ALDH-like Family: ALDH-like Phyre2 PDB 3ek1 chain C Region: 9 - 394 Aligned: 337 Modelled: 348 Confidence: 98.9% Identity: 19% PDB header:oxidoreductase Chain: C: PDB Molecule:aldehyde dehydrogenase; PDBTitle: crystal structure of aldehyde dehydrogenase from brucella2 melitensis biovar abortus 2308 Phyre2 PDB 3k2w chain D Region: 9 - 393 Aligned: 338 Modelled: 358 Confidence: 98.9% Identity: 19% PDB header:oxidoreductase Chain: D: PDB Molecule:betaine-aldehyde dehydrogenase; PDBTitle: crystal structure of betaine-aldehyde dehydrogenase from2 pseudoalteromonas atlantica t6c Phyre2 PDB 3efv chain C Region: 9 - 394 Aligned: 336 Modelled: 351 Confidence: 98.8% Identity: 17% PDB header:oxidoreductase Chain: C: PDB Molecule:putative succinate-semialdehyde dehydrogenase; PDBTitle: crystal structure of a putative succinate-semialdehyde dehydrogenase2 from salmonella typhimurium lt2 with bound nad Phyre2 PDB 1o04 chain A Region: 9 - 393 Aligned: 336 Modelled: 349 Confidence: 98.8% Identity: 17% Fold: ALDH-like Superfamily: ALDH-like Family: ALDH-like Phyre2 PDB 3lns chain D Region: 8 - 393 Aligned: 341 Modelled: 348 Confidence: 98.8% Identity: 15% PDB header:oxidoreductase Chain: D: PDB Molecule:benzaldehyde dehydrogenase; PDBTitle: benzaldehyde dehydrogenase, a class 3 aldehyde dehydrogenase, with2 bound nadp+ and benzoate adduct Phyre2 PDB 2d4e chain B Region: 9 - 393 Aligned: 337 Modelled: 347 Confidence: 98.8% Identity: 15% PDB header:oxidoreductase Chain: B: PDB Molecule:5-carboxymethyl-2-hydroxymuconate semialdehyde PDBTitle: crystal structure of the hpcc from thermus thermophilus hb8 Phyre2 PDB 3k9d chain D Region: 9 - 394 Aligned: 336 Modelled: 352 Confidence: 98.8% Identity: 16% PDB header:oxidoreductase Chain: D: PDB Molecule:aldehyde dehydrogenase; PDBTitle: crystal structure of probable aldehyde dehydrogenase from listeria2 monocytogenes egd-e Phyre2 PDB 3jz4 chain C Region: 9 - 393 Aligned: 335 Modelled: 351 Confidence: 98.7% Identity: 21% PDB header:oxidoreductase Chain: C: PDB Molecule:succinate-semialdehyde dehydrogenase [nadp+]; PDBTitle: crystal structure of e. coli nadp dependent enzyme Phyre2 PDB 1ag8 chain A Region: 9 - 393 Aligned: 337 Modelled: 351 Confidence: 98.7% Identity: 18% Fold: ALDH-like Superfamily: ALDH-like Family: ALDH-like Phyre2 PDB 3prl chain D Region: 9 - 393 Aligned: 343 Modelled: 359 Confidence: 98.7% Identity: 16% PDB header:oxidoreductase Chain: D: PDB Molecule:nadp-dependent glyceraldehyde-3-phosphate dehydrogenase; PDBTitle: crystal structure of nadp-dependent glyceraldehyde-3-phosphate2 dehydrogenase from bacillus halodurans c-125 Phyre2 PDB 3ros chain A Region: 9 - 398 Aligned: 343 Modelled: 356 Confidence: 98.7% Identity: 14% PDB header:oxidoreductase Chain: A: PDB Molecule:nad-dependent aldehyde dehydrogenase; PDBTitle: crystal structure of nad-dependent aldehyde dehydrogenase from2 lactobacillus acidophilus Phyre2 PDB 1ad3 chain A Region: 8 - 394 Aligned: 344 Modelled: 358 Confidence: 98.7% Identity: 14% Fold: ALDH-like Superfamily: ALDH-like Family: ALDH-like Phyre2 PDB 1vlu chain B Region: 9 - 360 Aligned: 317 Modelled: 335 Confidence: 98.6% Identity: 11% PDB header:oxidoreductase Chain: B: PDB Molecule:gamma-glutamyl phosphate reductase; PDBTitle: crystal structure of gamma-glutamyl phosphate reductase (yor323c) from2 saccharomyces cerevisiae at 2.40 a resolution Phyre2 PDB 3r31 chain A Region: 9 - 393 Aligned: 334 Modelled: 353 Confidence: 98.6% Identity: 16% PDB header:oxidoreductase Chain: A: PDB Molecule:betaine aldehyde dehydrogenase; PDBTitle: crystal structure of betaine aldehyde dehydrogenase from agrobacterium2 tumefaciens Phyre2 PDB 1a4s chain A Region: 9 - 393 Aligned: 336 Modelled: 347 Confidence: 98.6% Identity: 16% Fold: ALDH-like Superfamily: ALDH-like Family: ALDH-like Phyre2 PDB 2hg2 chain A Region: 9 - 393 Aligned: 337 Modelled: 349 Confidence: 98.6% Identity: 16% PDB header:oxidoreductase Chain: A: PDB Molecule:aldehyde dehydrogenase a; PDBTitle: structure of lactaldehyde dehydrogenase Phyre2 1 d1k75a_ 2 c2w8qA_ 3 d1ky8a_ 4 d1euha_ 5 c3ek1C_ 6 c3k2wD_ 7 c3efvC_ 8 d1o04a_ 9 c3lnsD_ 10 c2d4eB_ 11 c3k9dD_ 12 c3jz4C_ 13 d1ag8a_ 14 c3prlD_ 15 c3rosA_ 16 d1ad3a_ 17 c1vluB_ 18 c3r31A_ 19 d1a4sa_ 20 c2hg2A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1k75a_ 100.0 99 Fold:ALDH-like Superfamily:ALDH-like Family:L-histidinol dehydrogenase HisD 2 c2w8qA_ 99.1 16 PDB header:oxidoreductase Chain: A: PDB Molecule:succinate-semialdehyde dehydrogenase, PDBTitle: the crystal structure of human ssadh in complex with ssa. 3 d1ky8a_ 99.0 18 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 4 d1euha_ 98.9 14 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 5 c3ek1C_ 98.9 19 PDB header:oxidoreductase Chain: C: PDB Molecule:aldehyde dehydrogenase; PDBTitle: crystal structure of aldehyde dehydrogenase from brucella2 melitensis biovar abortus 2308 6 c3k2wD_ 98.9 19 PDB header:oxidoreductase Chain: D: PDB Molecule:betaine-aldehyde dehydrogenase; PDBTitle: crystal structure of betaine-aldehyde dehydrogenase from2 pseudoalteromonas atlantica t6c 7 c3efvC_ 98.8 17 PDB header:oxidoreductase Chain: C: PDB Molecule:putative succinate-semialdehyde dehydrogenase; PDBTitle: crystal structure of a putative succinate-semialdehyde dehydrogenase2 from salmonella typhimurium lt2 with bound nad 8 d1o04a_ 98.8 17 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 9 c3lnsD_ 98.8 15 PDB header:oxidoreductase Chain: D: PDB Molecule:benzaldehyde dehydrogenase; PDBTitle: benzaldehyde dehydrogenase, a class 3 aldehyde dehydrogenase, with2 bound nadp+ and benzoate adduct 10 c2d4eB_ 98.8 15 PDB header:oxidoreductase Chain: B: PDB Molecule:5-carboxymethyl-2-hydroxymuconate semialdehyde PDBTitle: crystal structure of the hpcc from thermus thermophilus hb8 11 c3k9dD_ 98.8 16 PDB header:oxidoreductase Chain: D: PDB Molecule:aldehyde dehydrogenase; PDBTitle: crystal structure of probable aldehyde dehydrogenase from listeria2 monocytogenes egd-e 12 c3jz4C_ 98.7 21 PDB header:oxidoreductase Chain: C: PDB Molecule:succinate-semialdehyde dehydrogenase [nadp+]; PDBTitle: crystal structure of e. coli nadp dependent enzyme 13 d1ag8a_ 98.7 18 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 14 c3prlD_ 98.7 16 PDB header:oxidoreductase Chain: D: PDB Molecule:nadp-dependent glyceraldehyde-3-phosphate dehydrogenase; PDBTitle: crystal structure of nadp-dependent glyceraldehyde-3-phosphate2 dehydrogenase from bacillus halodurans c-125 15 c3rosA_ 98.7 14 PDB header:oxidoreductase Chain: A: PDB Molecule:nad-dependent aldehyde dehydrogenase; PDBTitle: crystal structure of nad-dependent aldehyde dehydrogenase from2 lactobacillus acidophilus 16 d1ad3a_ 98.7 14 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 17 c1vluB_ 98.6 11 PDB header:oxidoreductase Chain: B: PDB Molecule:gamma-glutamyl phosphate reductase; PDBTitle: crystal structure of gamma-glutamyl phosphate reductase (yor323c) from2 saccharomyces cerevisiae at 2.40 a resolution 18 c3r31A_ 98.6 16 PDB header:oxidoreductase Chain: A: PDB Molecule:betaine aldehyde dehydrogenase; PDBTitle: crystal structure of betaine aldehyde dehydrogenase from agrobacterium2 tumefaciens 19 d1a4sa_ 98.6 16 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 20 c2hg2A_ 98.6 16 PDB header:oxidoreductase Chain: A: PDB Molecule:aldehyde dehydrogenase a; PDBTitle: structure of lactaldehyde dehydrogenase 21 c3iwkB_ not modelled 98.6 17 PDB header:oxidoreductase Chain: B: PDB Molecule:aminoaldehyde dehydrogenase; PDBTitle: crystal structure of aminoaldehyde dehydrogenase 1 from2 pisum sativum (psamadh1) 22 c3ed6B_ not modelled 98.6 17 PDB header:oxidoreductase Chain: B: PDB Molecule:betaine aldehyde dehydrogenase; PDBTitle: 1.7 angstrom resolution crystal structure of betaine aldehyde2 dehydrogenase (betb) from staphylococcus aureus 23 d1bxsa_ not modelled 98.6 15 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 24 c3ifgH_ not modelled 98.6 18 PDB header:oxidoreductase Chain: H: PDB Molecule:succinate-semialdehyde dehydrogenase (nadp+); PDBTitle: crystal structure of succinate-semialdehyde dehydrogenase from2 burkholderia pseudomallei, part 1 of 2 25 c3pqaA_ not modelled 98.5 18 PDB header:oxidoreductase Chain: A: PDB Molecule:lactaldehyde dehydrogenase; PDBTitle: crystal structure of glyceraldehyde-3-phosphate dehydrogenase gapn2 from methanocaldococcus jannaschii dsm 2661 26 d1o20a_ not modelled 98.4 13 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 27 c2jg7G_ not modelled 98.4 18 PDB header:oxidoreductase Chain: G: PDB Molecule:antiquitin; PDBTitle: crystal structure of seabream antiquitin and elucidation of2 its substrate specificity 28 c3rh9A_ not modelled 98.4 16 PDB header:oxidoreductase Chain: A: PDB Molecule:succinate-semialdehyde dehydrogenase (nad(p)(+)); PDBTitle: the crystal structure of oxidoreductase from marinobacter aquaeolei 29 d1uzba_ not modelled 98.4 21 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 30 c3r64A_ not modelled 98.4 16 PDB header:oxidoreductase Chain: A: PDB Molecule:nad dependent benzaldehyde dehydrogenase; PDBTitle: crystal structure of a nad-dependent benzaldehyde dehydrogenase from2 corynebacterium glutamicum 31 c3v4cB_ not modelled 98.4 16 PDB header:oxidoreductase Chain: B: PDB Molecule:aldehyde dehydrogenase (nadp+); PDBTitle: crystal structure of a semialdehyde dehydrogenase from sinorhizobium2 meliloti 1021 32 d1o9ja_ not modelled 98.3 16 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 33 c2o2qA_ not modelled 98.3 17 PDB header:oxidoreductase Chain: A: PDB Molecule:formyltetrahydrofolate dehydrogenase; PDBTitle: crystal structure of the c-terminal domain of rat2 10'formyltetrahydrofolate dehydrogenase in complex with nadp 34 c3b4wA_ not modelled 98.3 16 PDB header:oxidoreductase Chain: A: PDB Molecule:aldehyde dehydrogenase; PDBTitle: crystal structure of mycobacterium tuberculosis aldehyde dehydrogenase2 complexed with nad+ 35 d1wnda_ not modelled 98.2 18 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 36 c3i44A_ not modelled 98.2 16 PDB header:oxidoreductase Chain: A: PDB Molecule:aldehyde dehydrogenase; PDBTitle: crystal structure of aldehyde dehydrogenase from bartonella2 henselae at 2.0a resolution 37 c3qanB_ not modelled 98.2 18 PDB header:oxidoreductase Chain: B: PDB Molecule:1-pyrroline-5-carboxylate dehydrogenase 1; PDBTitle: crystal structure of 1-pyrroline-5-carboxylate dehydrogenase from2 bacillus halodurans 38 c3ju8B_ not modelled 98.2 16 PDB header:oxidoreductase Chain: B: PDB Molecule:succinylglutamic semialdehyde dehydrogenase; PDBTitle: crystal structure of succinylglutamic semialdehyde dehydrogenase from2 pseudomonas aeruginosa. 39 c1t90B_ not modelled 98.1 19 PDB header:oxidoreductase Chain: B: PDB Molecule:probable methylmalonate-semialdehyde PDBTitle: crystal structure of methylmalonate semialdehyde2 dehydrogenase from bacillus subtilis 40 d1vlua_ not modelled 98.1 12 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 41 d1bi9a_ not modelled 98.1 15 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 42 c2ve5H_ not modelled 98.1 17 PDB header:oxidoreductase Chain: H: PDB Molecule:betaine aldehyde dehydrogenase; PDBTitle: crystallographic structure of betaine aldehyde2 dehydrogenase from pseudomonas aeruginosa 43 c3hazA_ not modelled 98.0 21 PDB header:oxidoreductase Chain: A: PDB Molecule:proline dehydrogenase; PDBTitle: crystal structure of bifunctional proline utilization a2 (puta) protein 44 c2h5gA_ not modelled 97.9 13 PDB header:oxidoreductase Chain: A: PDB Molecule:delta 1-pyrroline-5-carboxylate synthetase; PDBTitle: crystal structure of human pyrroline-5-carboxylate synthetase 45 c3my7A_ not modelled 97.8 16 PDB header:oxidoreductase Chain: A: PDB Molecule:alcohol dehydrogenase/acetaldehyde dehydrogenase; PDBTitle: the crystal structure of the acdh domain of an alcohol dehydrogenase2 from vibrio parahaemolyticus to 2.25a 46 d1ez0a_ not modelled 97.5 14 Fold:ALDH-like Superfamily:ALDH-like Family:ALDH-like 47 c2vroB_ not modelled 96.2 16 PDB header:oxidoreductase Chain: B: PDB Molecule:aldehyde dehydrogenase; PDBTitle: crystal structure of aldehyde dehydrogenase from2 burkholderia xenovorans lb400 48 c2ax3A_ not modelled 81.9 18 PDB header:transferase Chain: A: PDB Molecule:hypothetical protein tm0922; PDBTitle: crystal structure of a putative carbohydrate kinase (tm0922) from2 thermotoga maritima msb8 at 2.25 a resolution 49 d2csua2 not modelled 80.3 13 Fold:Flavodoxin-like Superfamily:Succinyl-CoA synthetase domains Family:Succinyl-CoA synthetase domains 50 d1jcea1 not modelled 66.0 34 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 51 d2e8aa1 not modelled 59.4 23 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 52 d1bupa1 not modelled 58.5 23 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 53 c1e1cA_ not modelled 58.5 20 PDB header:isomerase Chain: A: PDB Molecule:methylmalonyl-coa mutase alpha chain; PDBTitle: methylmalonyl-coa mutase h244a mutant 54 d3bc8a1 not modelled 48.7 9 Fold:PLP-dependent transferase-like Superfamily:PLP-dependent transferases Family:SepSecS-like 55 c2q8nB_ not modelled 42.2 14 PDB header:isomerase Chain: B: PDB Molecule:glucose-6-phosphate isomerase; PDBTitle: crystal structure of glucose-6-phosphate isomerase (ec2 5.3.1.9) (tm1385) from thermotoga maritima at 1.82 a3 resolution 56 c3ljkA_ not modelled 37.8 16 PDB header:isomerase Chain: A: PDB Molecule:glucose-6-phosphate isomerase; PDBTitle: glucose-6-phosphate isomerase from francisella tularensis. 57 d1oi7a2 not modelled 37.6 15 Fold:Flavodoxin-like Superfamily:Succinyl-CoA synthetase domains Family:Succinyl-CoA synthetase domains 58 c2duwA_ not modelled 36.2 12 PDB header:ligand binding protein Chain: A: PDB Molecule:putative coa-binding protein; PDBTitle: solution structure of putative coa-binding protein of2 klebsiella pneumoniae 59 c3ic5A_ not modelled 35.6 23 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative saccharopine dehydrogenase; PDBTitle: n-terminal domain of putative saccharopine dehydrogenase from ruegeria2 pomeroyi. 60 c2csuB_ not modelled 32.5 13 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:457aa long hypothetical protein; PDBTitle: crystal structure of ph0766 from pyrococcus horikoshii ot3 61 c2dc0A_ not modelled 32.3 14 PDB header:hydrolase Chain: A: PDB Molecule:probable amidase; PDBTitle: crystal structure of amidase 62 d1vdra_ not modelled 31.0 18 Fold:Dihydrofolate reductase-like Superfamily:Dihydrofolate reductase-like Family:Dihydrofolate reductases 63 d1mt5a_ not modelled 30.9 13 Fold:Amidase signature (AS) enzymes Superfamily:Amidase signature (AS) enzymes Family:Amidase signature (AS) enzymes 64 c3ketA_ not modelled 30.8 17 PDB header:transcription/dna Chain: A: PDB Molecule:redox-sensing transcriptional repressor rex; PDBTitle: crystal structure of a rex-family transcriptional regulatory protein2 from streptococcus agalactiae bound to a palindromic operator 65 d2dt5a2 not modelled 29.2 15 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Transcriptional repressor Rex, C-terminal domain 66 c3jstA_ not modelled 27.9 14 PDB header:lyase Chain: A: PDB Molecule:putative pterin-4-alpha-carbinolamine dehydratase; PDBTitle: crystal structure of transcriptional coactivator/pterin dehydratase2 from brucella melitensis 67 d1ulza2 not modelled 27.3 27 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:BC N-terminal domain-like 68 d1dkgd1 not modelled 26.9 25 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 69 d1xpma1 not modelled 25.1 13 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 70 c2khoA_ not modelled 24.7 25 PDB header:chaperone Chain: A: PDB Molecule:heat shock protein 70; PDBTitle: nmr-rdc / xray structure of e. coli hsp70 (dnak) chaperone2 (1-605) complexed with adp and substrate 71 c3lehA_ not modelled 24.7 13 PDB header:transferase Chain: A: PDB Molecule:putative hydroxymethylglutaryl-coa synthase; PDBTitle: the crystal structure of smu.943c from streptococcus mutans ua159 72 c1x9eB_ not modelled 24.4 14 PDB header:lyase Chain: B: PDB Molecule:hmg-coa synthase; PDBTitle: crystal structure of hmg-coa synthase from enterococcus2 faecalis 73 d2iela1 not modelled 24.1 29 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:Universal stress protein-like 74 d1sp8a1 not modelled 23.7 16 Fold:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Superfamily:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Family:Extradiol dioxygenases 75 c3ilmD_ not modelled 23.7 19 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:alr3790 protein; PDBTitle: crystal structure of the alr3790 protein from anabaena sp. northeast2 structural genomics consortium target nsr437h 76 c2vyaB_ not modelled 21.9 13 PDB header:hydrolase Chain: B: PDB Molecule:fatty-acid amide hydrolase 1; PDBTitle: crystal structure of fatty acid amide hydrolase conjugated2 with the drug-like inhibitor pf-750 77 d1k1va_ not modelled 21.2 11 Fold:A DNA-binding domain in eukaryotic transcription factors Superfamily:A DNA-binding domain in eukaryotic transcription factors Family:A DNA-binding domain in eukaryotic transcription factors 78 d1oi7a1 not modelled 20.1 17 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain 79 d2j9ga2 not modelled 19.3 19 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:BC N-terminal domain-like 80 c3ff1B_ not modelled 19.2 24 PDB header:isomerase Chain: B: PDB Molecule:glucose-6-phosphate isomerase; PDBTitle: structure of glucose 6-phosphate isomerase from staphylococcus aureus 81 d1iuka_ not modelled 18.5 15 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain 82 c3mogA_ not modelled 18.2 13 PDB header:oxidoreductase Chain: A: PDB Molecule:probable 3-hydroxybutyryl-coa dehydrogenase; PDBTitle: crystal structure of 3-hydroxybutyryl-coa dehydrogenase from2 escherichia coli k12 substr. mg1655 83 c2ebbA_ not modelled 18.0 21 PDB header:lyase Chain: A: PDB Molecule:pterin-4-alpha-carbinolamine dehydratase; PDBTitle: crystal structure of pterin-4-alpha-carbinolamine2 dehydratase (pterin carbinolamine dehydratase) from3 geobacillus kaustophilus hta426 84 d1y81a1 not modelled 17.7 16 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain 85 c3h0rP_ not modelled 17.6 11 PDB header:ligase Chain: P: PDB Molecule:glutamyl-trna(gln) amidotransferase subunit a; PDBTitle: structure of trna-dependent amidotransferase gatcab from2 aquifex aeolicus 86 c2dt5A_ not modelled 17.5 13 PDB header:dna binding protein Chain: A: PDB Molecule:at-rich dna-binding protein; PDBTitle: crystal structure of ttha1657 (at-rich dna-binding protein) from2 thermus thermophilus hb8 87 c1txtB_ not modelled 17.1 13 PDB header:lyase Chain: B: PDB Molecule:3-hydroxy-3-methylglutaryl-coa synthase; PDBTitle: staphylococcus aureus 3-hydroxy-3-methylglutaryl-coa2 synthase 88 c1zcjA_ not modelled 17.1 10 PDB header:oxidoreductase Chain: A: PDB Molecule:peroxisomal bifunctional enzyme; PDBTitle: crystal structure of 3-hydroxyacyl-coa dehydrogenase 89 c3hl2D_ not modelled 17.0 11 PDB header:transferase Chain: D: PDB Molecule:o-phosphoseryl-trna(sec) selenium transferase; PDBTitle: the crystal structure of the human sepsecs-trnasec complex 90 d1sqda1 not modelled 16.8 13 Fold:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Superfamily:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Family:Extradiol dioxygenases 91 c3k2gA_ not modelled 16.2 22 PDB header:resiniferatoxin binding protein Chain: A: PDB Molecule:resiniferatoxin-binding, phosphotriesterase- PDBTitle: crystal structure of a resiniferatoxin-binding protein from2 rhodobacter sphaeroides 92 d1sqia1 not modelled 16.1 7 Fold:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Superfamily:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Family:Extradiol dioxygenases 93 d1euca1 not modelled 15.9 31 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain 94 c2kw3A_ not modelled 15.8 31 PDB header:dna binding protein Chain: A: PDB Molecule:dna-binding protein rfx5; PDBTitle: heterotrimeric interaction between rfx5 and rfxap 95 c3nkgA_ not modelled 15.4 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein geba250068378; PDBTitle: crystal structure of geba250068378 from sulfurospirillum deleyianum 96 c3en0A_ not modelled 14.9 15 PDB header:hydrolase Chain: A: PDB Molecule:cyanophycinase; PDBTitle: the structure of cyanophycinase 97 c3tl8K_ not modelled 14.8 18 PDB header:transferase/ligase Chain: K: PDB Molecule:effector protein hopab2; PDBTitle: the avrptob-bak1 complex reveals two structurally similar2 kinaseinteracting domains in a single type iii effector 98 d2gi3a1 not modelled 14.8 17 Fold:Amidase signature (AS) enzymes Superfamily:Amidase signature (AS) enzymes Family:Amidase signature (AS) enzymes 99 c2v6uB_ not modelled 14.6 10 PDB header:lyase Chain: B: PDB Molecule:pterin-4a-carbinolamine dehydratase; PDBTitle: high resolution crystal structure of pterin-4a-2 carbinolamine dehydratase from toxoplasma gondii

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0