>ss_pred
CCCHHEEEHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEEEEECCEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEECCHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHCCCEEECCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEEEEEEEEECHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
>ss_conf
97012001688998999997303256871679999999999999733899999999846997312242889999888609989999999999999999984148880785279859627987420148871799731356888865737660897589987989889999999981900323405578888876401456765577769978999999997078775534766798048999758888999999999873048998489984838999999999999987388278999996238389989989999998651841044212358999886200503312588802125313477886878985345469978671401056997899999899999999986180589999999999777329
>batch____
MSFNTIIDWNSCTAEQQRQLLMRPAISASESITRTVNDILDNVKARGDEALREYSAKFDKTTVTALKVSAEEIAAASERLSDELKQAMAVAVKNIETFHTAQKLPPVDVETQPGVRCQQVTRPVASVGLYIPGGSAPLFSTVLMLATPASIAGCKKVVLCSPPPIADEILYAAQLCGVQDVFNVGGAQAIAALAFGTESVPKVDKIFGPGNAFVTEAKRQVSQRLDGAAIDMPAGPSEVLVIADSGATPDFVASDLLSQAEHGPDSQVILLTPAADMARRVAEAVERQLAELPRAETARQALNASRLIVTKDLAQCVEISNQYGPEHLIIQTRNARELVDSITSAGSVFLGDWSPESAGDYASGTNHVLPTYGYTATCSSLGLADFQKRMTVQELSKEGFSALASTIETLAAAERLTAHKNAVTLRVNALKEQA
>UniRef50_Q2HFX2(419-812:817) Putative uncharacterized protein n=1 Tax=Chaetomium globosum RepID=Q2HFX2_CHAGB  E=9e-89 s/c=0.84 id=50% cov=88%
-----------------------PKEAAPERITMKVFDMATASRKELDEALRRPSQKSSDTIMKIITPIIDDTSPVLKapfpeslmQLPTETIKAMDVSFENIRKFHAAQKeEKPLQVETIPGVVCSRFSRPPEAVGLYVPGGTAVLPSTAFMLGVPAMVAACKKIVLASPP----------------------RSDAVAAMAYGTESVSKVDKILGPGNQFVTAAKMFVSNDTNaGVGIDMPAGPSEVLVIADKDANPAFVASDLLSQAEHGVDSQVILiaidLTDAQLLA--IEDEVHKQAMALPRVDIVRGSIAHSLTVRVKTVDEAMEISNQYAPEHLILQIKDAESVVDKVMNAGSVFIGEWTPESVGDYSAGVNHSLPTYGYAKQYSGVNLASFVKHITSSNLTAEGLRNVGEAVMQLAKVEELEAHRRAVSIRL-------
>UniRef50_A8RCE7(18-424:427) Putative uncharacterized protein n=1 Tax=Eubacterium dolichum DSM 3991 RepID=A8RCE7_9FIRM  E=3e-87 s/c=0.80 id=45% cov=93%
---------------EERRVVMNPAL-----IGR-VSAILEDVRMHGDEAVLRYTKQFDGMELNKLRVSSEELNAQADLCTPEFRRSMQQAKENILFYHQAQISKGYRLEKEMGIYLGQRVLPLDSVGIYVPGGSAQYPSSVLMNALPARLAGVKRIVMLTPPskegSIHTNIALAAKLVGIDEVYKVGGAQGIAALAYGTQSIAKVDKIVGPGNVYVACAKKLVFGDVD---IDMIAGPSEILVIGDEGANPKWIAADLLSQAEHDPQASAVLLAVSQNMVDAVKQELQKQTRCLPRQKIIHESLeNYGLALVCESLQQCVDISNQIAPEHLELMVDKPEELLPLVRHAGSVFLGYATCESVGDYFGGTNHVLPTGGTARFFNPLGVDSFVKKSSYLHYSIEALQAYGDSIITLAEAEQLQAHANAVKVR--------
>UniRef50_C0QG33(3-430:432) Histidinol dehydrogenase n=4 Tax=Deltaproteobacteria RepID=C0QG33_DESAH  E=8e-80 s/c=0.70 id=43% cov=97%
-----IYTYPSPEGEQRICDTLKRGLGFTPENQRAVEAYIEDVRTRGDQALVEYTNQFDSSQVTrdTLKVSQQEIEEAKTLVDSDFSRALDRAVDQLGTFHSRQRQNSWIDTPRNGVMVGQMVNPVDAAGIYAPgakGGKTPLVSSVLMGGIPARVAGVKSCCLMTPPmengKINPYMLVAADRVGINAIFKAGSAWAIAALAFGTESVPKVDVIVGPGNIFVTLAKKIVSGIV---GIDMIAGPSEILIIADKGANPDHIAADLLSQAEHDPMASAILVTDSMEMATRTKAALEIQVKALGRRQIAQRSIDDFGAIMkVPDIDTAIALANRLAPEHLELIVDNPFDQVGKIKNAGAVFLGPYTPEPMGDYIAGPNHVLPTAGTARFSSALGVDNFTKRTSLINYSKEAFDREAQDVMVLANIEGLGAHANSVRIR--------
>UniRef50_A9A5X6(11-419:420) Histidinol dehydrogenase n=2 Tax=Thaumarchaeota RepID=A9A5X6_NITMS   E=2e-66 s/c=0.62 id=37% cov=93%
--------------------LKKIGTKDSSKNQKIVKSILKDVKKNGDVAVKKYEKKFS-AKVSSLRVSQRDIASAYFKVSKEDISAIKLAKSRLSKAESAVRRQFKDITIKSnGTKLSKSFVPIDSVGCYVPGGAARYPSSAIMSVVPAKIAGVKRIVVVSPPNSSGNIdpltIVAADLCGATEIYKTGGVQSIAALTYGTRSIKKVNKIVGPGGAFVTLAKYLVSNIV---SIDMMAGPTELGIVIDSAADVDVAALDLISQAEHSSDTFCYALTTSNSIAKKIQSSVNSKLKDIQRVKIVKSSLESNGFIGVCKPSDIIDIANDLAPEHLEIISKNPKKW-NKIKNPGLILYGKNSPSSASDYLLGSNHILPTNGFGKTRGSLSVLDFVKLLTKIETTKKDLQKISKSMKNLTLAEGLPNHYEAVRGRL-------
>UniRef50_C3XDE7(4-452:452) Histidinol dehydrogenase n=1 Tax=Helicobacter bilis ATCC 43879 RepID=C3XDE7_9HELI  E=2e-66 s/c=0.57 id=37% cov=98%
-----ILNIHDKDFETEFNTLLARANTDMDSIIPEVLKTLQDIKQRGEDALLDIVRKYDSwnpQTFNDLKIAEEDTFNAYKNLDSKTKDALQIAHDRIYTFHAKNAPKGFIYHDEYANMLGQNIMPIQRAGIYIPGGKAFYPSSLLMNAIPAKVAGVKEIIMASPTPnnhINELVLAAMYLCGIKEGYKIGGIGAIGMFAYGfgetkwskdslfshtkttQKGFKKVDVITGPGNIYVATAKKLVFGEVN---IDMIAGPSEIGIIADSHANSDYLAIDMLSQAEHDSMASAILITDNKDLAKEVAQKIDTKLTHLMRKDIAQKSIQErGAIIIVENLKQAAMLMNAIAPEHLEIVTQEPFSLLGEIKAAGAVFLGHYTPEAIGDYLAGPNHTLPTGGSARFFSPLGVEHFCTRSSLISFSKQGIKNLANPCAILAETEGLEAHKLSVISRLDSMKD--
>UniRef50_A0R401(17-435:451) Histidinol dehydrogenase n=2 Tax=Actinomycetales RepID=A0R401_MYCS2   E=1e-61 s/c=0.57 id=38% cov=91%
-------------------------------VVERVSQMLLDIERRGLDAVRAYARELDGWS-GPLEIGADELRKSGDALPADLREALELGYERTNRFAVAQraRLTDFEIELAPGVTGGVQYVPVNRVGAYLPAGRFPLLASAFMTVGVAKAAGVPTVLACTPPSgehgAHPAVLYGAYLSRADSVFAVGGVQALGAMAFGLIGDGPVDMLVGAGNAFVTEAKRQLFGRV---GIDLLAGPSEVAVLADETADPEWVAADLLGQAEHGPNSPAALITTSETLGRRVIEAIDRQLETLATREVAGPAWrDFGSVLVASDAEQAAAIADVLGPEHLEVQTADDDYFLKRLRNYGSLFLGRWSTVAYSDKGiAGTNHVLPTGKTARYNAGLSVSRFVKPLTYQRAAREATAALAPAVERISAFEGLAAHEATATIRIEEI----
>UniRef50_B1ZNB2(28-429:431) Histidinol dehydrogenase n=3 Tax=Verrucomicrobia RepID=B1ZNB2_OPITP   E=8e-56 s/c=0.55 id=39% cov=90%
-------------------------------ITESVAAILADVRERGDEAVVYYAAKFDGAKLRArdLRVKPSDLTVAAKRLPAAERRALVAARDSIMDYNR-RGLPRGWTAKNPhGAMVGEKFDPLRRVGLYVPGGQVPLVSTVLMTVTLAKIAQCPQVVVFTPcnaeGKIADGLLAALHLLGVDEVYRVGGVQAIGAMAFGTTTIPPVDKIFGPGNAYTCEAMRQV---FGIVGVNGLPGPSELMVIADDTARADYAAADLLAQAEHGSGREKVYLV--ATSSRVITEIVNEmngQLQTLTRSEKTQRVLEQGFLaIEVGSMQQAAAVANYVAPEHleLLVSEAAVKQLTKAVTTAGAIMIGNETPTALGDFTAGPSHVLPTGRAGRFFSGMRVSDFLRRTSLVRYDRKSVRKGAPVVAAFAAMERLDAHGRSVKIR--------
>UniRef50_Q492K3(10-436:443) Histidinol dehydrogenase n=542 Tax=Proteobacteria RepID=HISX_BLOPB   E=1e-178 s/c=1.47 id=54% cov=99%
------IYWNDCSKSEQKKLLTRPINNKLNDIYINVKNILTKVYNEGDRALFKFNFDFDNVQTTQLQIPTEIIMNSGRNLSNEIKQAIHTAMTNITRFHQAQCYSEIIVETLPGVYCQQIIRPLNIVGLYVPGGTAPLLSTVMMLGVPARIAKCKRVILCSPPPIPDVIIYTAQLCGIDEIYQIGGSQSIAAMGFGTESIPKVDKIFGPGNIWVTEAKRQINLAPNGAAIDMLAGPSEILIIADNTANPIFIAADLLSQSEHGPDSHAILITPYSCIAEKTKKELHKQLKILPRNDIVRNVLLNSRMIITNNLMECFSISNSYAPEHLIIQIENASDYLHYITNAGSIFLGNWSPETAGDYASGPNHVLPTYGRAVATSGLGVIDFQKRMSVQQLTQNGLLQLSSTITTLTQIEQLKAHEYAITHRINYIKEQ-
>UniRef50_Q8R882(17-427:430) Histidinol dehydrogenase n=7 Tax=Clostridia RepID=HISX_THETN   E=1e-171 s/c=1.47 id=45% cov=92%
----------------------RSKLENKE-IAKRVEDIIENVRERKDKALFEYTYMYDGINLnsETVKVKEEEIKRAYEEVKEDFLKALDKAIKNITEFHEKQKEKTW-MDFKEGIVYGQVLRPLSSVGIYVPGGTASYPSSVLMNGIPAKVAGVERIVMVSPAgkkGISPYVLVAADKIGIKEIYKIGGAQAVAALAFGTESIPKVDKIVGPGNIYVAMAKRALYGYVD---IDMVAGPSEILVIADESASPKYVAADLLSQAEHDVMASSILVTTSKELAEKVKKEIERQMEYLERKEIIAESLKNfGAIIVIDNLKEAIGIANEIAPEHLELVIENPFEILGEIKNAGAVFLGEFSPEPLGDYLAGPNHVLPTSGTARFFSPLSVRDFVKKMNVLYYSKEALSSVKDDVITLAEAEELTAHANSVKVR--------
>UniRef50_Q8YSM8(3-430:431) Histidinol dehydrogenase 1 n=16 Tax=Bacteria RepID=HISX1_ANASP   E=1e-163 s/c=1.35 id=42% cov=95%
----------------RFQSLVSDRREATVDVSGTVRDILAHVKARGDAAVQEYTSRFDHYRPHSHHLSAAFIAEQAAKCSDEVKAALELAAERISSFHQKQLPQDIGYTDTAGVKLGLNWVALSQVGIYVPGGRASYPSSVLMNALPAKIAGVERIVMTVPMPhgeINPAVLAAAQVAGVTEIYSIGGAQAVGALAYGTETITPVDKIVGPGNAYVAEAKRQVFGTV---GIDSIAGPSEILVVADRQNNPEWIAWDLLSQAEHDPSAQSILITDSESFAQQVIAAVEQILTTLPSQKVASSSWqNHGAVIIVRDLAESIPLLNQLAPEHVELCVDNPQLLASQIKCAGSLFLGRYTPEAIGDYLGGPNHVLPTSRSARFASGLSVYDFLKRITYLECNQAALQKIGQSAVTLAETEGLPAHAGSVAVRLQGLKD--
>UniRef50_A9NV24(53-489:491) Histidinol dehydrogenase n=2 Tax=Spermatophyta RepID=A9NV24_PICSI   E=1e-163 s/c=1.32 id=47% cov=97%
----------DLHSTQIDHLKARPRIDFS-SMFGVVGPIIEDVRKRGDVAVIDYTTKFDGVNLDKVVECVADLPD--PKLDSAVQAAFDVAYDNIRAFHAAQRNPERVVENMKvgsvlgrGVMCKRVARSIDSVGLYVPGGTAVLPSTALMLAVPAQLAGCRIIILASPPrpdgSICKEVLYCAKKAGVTHILKAGGAQAISAMAWGTTSCPKVEKILGPGNQYVTAAKMILQNSEAMISIDMPAGPSEVLVIADKHANPVYIAADLLSQAEHGPDSQVVLVLVGEGVnLDEIEMELEKQCKSLPRGQFAAKALTHSFTVLARNKAEAISFSNLYAPEHLIINVEDADQWVDYIENAGSVFLGRWSPESIGDYASGTNHVLPTYGYARMYGGVSLDSFMKYITVQSLTEEGLKSLGPHVVKMAEVEGLEAHKRAVTLRLQDIE---
>UniRef50_B9D1F9(10-431:431) Histidinol dehydrogenase n=2 Tax=Campylobacter RepID=B9D1F9_WOLRE   E=1e-163 s/c=1.37 id=39% cov=95%
-----------------FAALVNRSNGDMSAVTPAVSQILEDVRARGDEALFEQIEKFDRWKPDtnSLKIGTEEMQKAYDGIDSCLRNALNLAFERIKSYHEKSLPKTWMEHDEHGVLLGAKYTPLDRAGLYIPGGKAAYPSSLLMNAVPALVAGVGEIAVCTPavgGKVNTLLLAAMHICGIKEAYKVGGASAVAAMAYGTQTIKKTDVITGPGNIYVATAKKLVYGEVN---IDMIAGPSEICVIADESADPRHIAVDLLSQAEHDEMASAVLITPNQAFGAAVQRHINEEIKTLARQPIAQASIDkKGAIIVASDLGECVRLANELAPEHLEIATNDAMELARQIRHAGAIFIGHFTPEAMGDYLAGPNHTLPTGGSARFYSPLGVENFMKRTSLISLNAKGISELANACMELAEAEGLGAHRRSVVVRLEALK---
>UniRef50_D0RRH1(3-428:429) Histidinol dehydrogenase n=1 Tax=alpha proteobacterium HIMB114 RepID=D0RRH1_9RICK  E=1e-162 s/c=1.34 id=40% cov=92%
---------------------------QSNNSQKIVKKIISDIKKNGDLALIKYTKRFDKVNfgPSKIKLDDKLISKKIKKLDINIKKSIDLAFNRITKFHKKQVHKGFKFKDKLGNQLGYKILPLDKVGVYVPGGTASYPSTLLMNSIPAMVAGVKNIYCVMPTPkdeINAGVLYAAKKCKIKSIFRIGGAQAVAALTYGTKNVPKVDKIVGPGNIFVATAKKEVFGTV---GIDMVAGPSEITVIADDRNRADWTAVDLLSQAEHDVLSQSILLTTSEKFAKQVSLEVKKILKTLPRKKIASKSIkNYGCIVVCKNKKELVDYANIIAPEHLEIKIKGSEKLEKQIKNAGSIFLGEFSPEAIGDYLAGPNHVLPTSGSARFASGLSVNDFLKRTSLIKCTKRGIEKIGQMAINLANYEGLHAHALSVSKRIK------
>UniRef50_B3WED5(7-429:430) Histidinol dehydrogenase n=21 Tax=Bacilli RepID=B3WED5_LACCB   E=1e-159 s/c=1.34 id=42% cov=97%
-----------LSQLKQQVDIRRTAVAQNTDVQTIVQAIIAKVRAEGDSALRTYSNKLDHVTVNDFQVDQALIDAAPAQLPAKLLKALQLAKANITSYHQNEIERGFVDTPNSGIIRGQKITPLAAVGLYVPGGTAAYPSTILMTAIPAKLAGVKKIVMVTPPQpdgLNPVVLAAANLAGVDAIYQVGGAQAIAALAYGTESIPRVDKIMGPGNRYVAEAKKQVFGNV---AIDMIAGPSEIGIIADESADPIRLAADLLSQAEHDPNARAMMVTTSEKLASAVSEQIDIQLPTLPRESIARAAIENqGFIAIVATINDAFSLMNTIAPEHLEVQLPDPITYLAQIQNAGSVFLGQNAAEPVGDYVAGPNHVLPTAGSARFFSPLGVYDFVKRTQFIQYSSEALASQADAIVTLAQAEGLDGHAEAIIKRVPAAKE--
>UniRef50_Q5FS83(4-429:430) Histidinol dehydrogenase n=3 Tax=Bacteria RepID=HISX_GLUOX   E=1e-159 s/c=1.33 id=43% cov=95%
--------------SEDFATLLAARGSDERSVAEPVRAILADVRSRGDEALCDYTARFDRLTLpaEKLRISAEEIASEAARVPADLMDALRTAARRIETFHAAQMPKDLDFTDEDGIRLGMRWTPLDAVGLYVPGGKAAYPSSVLMNALPARVAGVKRLAMCVPSPdgvLNPLVLAAAQLCGVEEIYRIGGAQAVGAMAFGTDLIAPVDRIVGPGNAYVAEAKRQVFGHV---GIDSIAGPSEVVVVADGQNDPRLVALDLLAQAEHDEQAQAILITTDAAFAERAAEAVRKELETLPRTAIASKSWeDHGAIIVVRSLEEAAEIVNALAPEHLEVMLDAPRDFSAMIRHAGAIFMGRYCPEAVGDYVGGPNHVLPTSRTARFASGLSVFDFIKRTTTIEADEAGLRRIGPAGVALAKAEGLDAHALSLSVRLEK-----
>UniRef50_C1PFR7(25-426:427) Histidinol dehydrogenase n=1 Tax=Bacillus coagulans 36D1 RepID=C1PFR7_BACCO  E=1e-159 s/c=1.40 id=38% cov=91%
-----------------------------EGVLRTAKEVLEDIRLNGDAAVKKYTAKFDGEVPESWEVLPEERKQAWHEVPQDVISALQKAAENIRRFHAKQLQNSRIMEMNENIISGQLFRPVEKAGIYVPGGTACYPSSVLMNAIPAVLAGVEEVIMATPArngtKIAPVLSVAADIAGVGTIYKLGGIQAIGALAYGTETIPKVDKIVGPGNAYVAAAKSLVYGTV---GIDMIAGPSEVAIIADENANPVYIAADLIAQAEHDERARTFLFTTSQKLINETKSALEKQLVVLPRRDIGEVSIKmQSAAVLVESIDEAFALSNRLAPEHLEIQVENPLLQLSKVKNAGSVFLGENTPEAIGDYYGGPNHILPTSGTARFSSGLSVDDFYKKITYLYYGEKALQQAAPDVMAIATEEQLAGHARAVQKRVK------
>UniRef50_C7LV94(23-434:436) Histidinol dehydrogenase n=6 Tax=Desulfovibrionales RepID=C7LV94_DESBD  E=1e-157 s/c=1.35 id=40% cov=91%
-----------------------------DNVEPLVRDILAQVRERGDEAVAEYTRRFDCPSLSAagLPVPKADIGRALELIPAEDAAIIREAAANIRDFHLRQKQNSWITTPAPGTTLGQLVLPVDRAGLYVPGGQGgetPLISSLLMNAIPAQVAGVGAICVVSPPrkdgTLNPYILATAAILGIDTIFMCGSAWAIAALAYGTASIPRVDVIAGPGNIFVTTAKRLL---VGQVGIDMIAGPSEIAILADSTANPKWLAADMLSQAEHDPLASSILISADQQLLEEVKKELARQLPALPRQEIASKSLsEWSALIHVPDLEMGMDLINRLAPEHFELSVADPWALVGAVRNAGAVFMGHSTPEPVGDYFAGPNHVLPTLSTARFSSALSVDTFCKKTSLICTDQAYMNSHGSKVARLARLEGLEAHARSVEQRLE------
>UniRef50_Q186D5(18-421:421) Histidinol dehydrogenase n=9 Tax=Bacteria RepID=Q186D5_CLOD6   E=1e-157 s/c=1.38 id=40% cov=91%
-------------------------------LREQVSSIIEDIRNNKDVALKKYNEKFDRNTRDEFRITKEEIKEAYKHVDDEFINNLKIAAKNIREFAKAQKLsfeNPFEKEIYPGVILGQTNIPIESCLAYVPGGQYPLFSTALMLIIPAKVAGVKRIVACSPTmknteKINPKTLVAMDIAGADEIYATGGVQAIAAFTYGTEKINPVDIIVGPGNKFVTEAKRQCYGQV---GIDFVAGPSEVLIIADETSNPVYIAADLLAQCEHDLNARGILLTNSLEVAQKVEKNIESMLKDLPTKDISYSSWeNNGEIILVDDMEEAIKISNFYAPEHLEVAVNEYNDICDRLTNYGSLFIGNLSAEVFGDYVSGTNHTLPTLKASRYTGGVWVGTFIKTCTKQIFNEKAIQSLAPVAEKLAKEEGLYAHAKAAEVRFKK-----
>UniRef50_D1YWF4(2-423:423) Histidinol dehydrogenase n=1 Tax=Methanocella paludicola SANAE RepID=D1YWF4_METPS  E=1e-156 s/c=1.32 id=40% cov=94%
------------DDAALDEVFKRR--TSISSVMDTAKKVADEVREGGDAAVRKYTKQFDGVDLRDLEVTDDEMYNAVELIDYETIGHLEKAIDNIEAFHALQRPSGdmWLTEISPGIRLGQKFTPLERIGAYVPGGTGSYPSTALMLIVPAQVAGVSEIIACTPPrkdgTIHPLTLTALDMAGADRIFKVGGVQAIAAMAYGTQSIPKVEKIVGPGNIYVTAAKMYVR---DAAEIDMPAGPSEIVVIADDTAIPSFIASDMIAQAEHDVNAMSILLTPSEMLAESVELEIERQKENAPRRQIIDKA--GMGIYVLDDLDAAVEVCNRIAPEHVEIMVRDPMSTLNKVRNAGTVYVGDYAPVAAGDYASGANHVLPTGGYAKVFSGMNTMQFIKTTSVQVIEKGGLEGIKDTITALAEIEGFDAHARSVYKRFE------
>UniRef50_Q87C29(3-429:431) Histidinol dehydrogenase n=66 Tax=cellular organisms RepID=HISX_XYLFT  E=1e-154 s/c=1.28 id=51% cov=98%
-----IIDWNQLDTAAQAKTLTRPAQTIATQTREAVTALIEQVRRGGDTALRDITARFDGVDLATFEVTAAELAAAATAVAPELQHAMQTAAARIEAFHRAGMTNDYRVETAPGVVCERLVRPIARVGLYVPAGSAPLFSTALMLGVPARLAGCREVVLCTPPSKdgraNPAVLLAARLTGVTRVFTLGGAQAIAAMAYGTASVPTCDKVFGPGNSFVTEAKQQLA-QAGVVAIDMPAGPSEVLVIADAAANPAFIAADLLSQAEHGPDSQVLLLSDSDALMTAVQNALALQLQQLSRAEIARQALAHSRFIKVATLETAFDISNRYAPEHLILALRQPRAWLHRVAAAGSVFLGDYTPEALGDYCSGTNHVLPTGGAARAYSGVSVSSFQNMISVQAASRSGIAEIGGCALTLARAEGLDAHANAVALRMGS-----
>UniRef50_A5D1M4(5-432:437) Histidinol dehydrogenase n=1 Tax=Pelotomaculum thermopropionicum SI RepID=A5D1M4_PELTS  E=1e-151 s/c=1.25 id=37% cov=95%
---------KEMSAEDYNRIMKRSEVE-TDSVIGEVKKVIADVKSRGDDALVDYTREFDGITISAekIRVSPEEIKEAYHKVDRETVEAIKTLAGNVRRFHAAQMPNKmWSMEVSPGLVAGQVIIPLDRVGCYVPGGRGWFPSAVMMSVLPARVAGVPEVIVCTPsapdGSVPPGTLVACDICGADAVFRIGGSQAVAAMAYGTQTVPKVDKIVGPGSKWVLAAFKLLYGEVE---IGTHAGPGEGLIIADETADPEFAAADICIQAEHGLDSAGVLVTHVEELAWAVQKKIARHIERLNeyRKNFVVESLkKYGAIIITSSLEESIAFANDYAVEHLEIMTRDPLHVMQKIKNAGGIYLGHYTPLSCGCFGSGPNHVLPTGRKAKVSGGLKTADFYKAVTFEYLSREGLASLKDAMVKLAEYEGFPAHGNAILER--------
>UniRef50_Q01ZU1(5-412:423) Histidinol dehydrogenase n=1 Tax=Candidatus Solibacter usitatus Ellin6076 RepID=Q01ZU1_SOLUE  E=1e-150 s/c=1.31 id=42% cov=92%
-------------------LLKRKAARFTEA-EAVVTPILEAVRKRGDRALMDYARQFDQLQRKSVRVPEGELLAARDGLTPEFRGAIETAAPNIRAYAGRQMPREWNRSFGAGLQLGQLVRPLDAVAAYIPAGRYPLPSTVMMTVIPAQVAGVPNICIACPKPVA-EVYGTAAMLGVRNVFQMGGAQAIAAFAFGTRTVPRADRIVGPGNIYVAAAKKLLAGEV---GIDFIAGPTEILIIAADG-DPRHFAADMLAQAEHDVDASAILLTTSKRLAAAVSRELERQLAILPTAPVASKSIaKNSAIILVRSLDEALEISNRFAPEHLSIPDA---SLLPGVRHAGSVFVGPYSPEAAGDYASGPNHVLPTSGAARQRGGLSVTDYVKVISVQNLTEPALRRLAPSITTLARAEGLEAHARSVEVRL-------
>UniRef50_P62460(5-411:412) Histidinol dehydrogenase n=15 Tax=Bacteria RepID=HISX_THET2   E=1e-147 s/c=1.29 id=42% cov=94%
-------------AEEVRARFARRGLSFDPTVEEIVRGILEAVREEGDEALDRFSRDLDGYPVE--EVPKRAWREAYEDLDEDLRDALETARERIEAFYREEARGGF-LRAEGGGVLAQLVRPLERVGVYVPGGSAPLLSTLLMTVVPAKVAGVREVIVASPPKVHPGVLAAAWVAGADRLFAMGGAQAIAALAYGTGRVPRVDKIVGPGNRYVVAAKRLVYGTV---GIDGLAGPTETMIIADGSASPRLLAADLLAQAEHGPDSEPWLLSPDRALLERVEAELSRQLQDLPRAEVARQALEKGGLVLTKDLEEAFALANLYAPEHLSLALSDPLPWLEKVQNAGGVFLGEGSPEALGDYIAGPSHVMPTSGTARFQGGLAVRDFLKVIPVVGLSEGAARELAKKGALLARAEGLEGHARSLDLR--------
>UniRef50_C4L171(11-405:405) Histidinol dehydrogenase n=1 Tax=Exiguobacterium sp. AT1b RepID=C4L171_EXISA  E=1e-147 s/c=1.33 id=38% cov=89%
---------------------------------EAVKPIVESIEARGDEALLKWTKQFDGVD----RIESVDLASFNPPVAyAELTEALSLAAERIRTFHARQVRQDDVFEDTM-FRLGRRYMPLDSVGVYVPGGTAVYPSSVLMNIIPAKVAGVKRVVMVTPPKADGIdisLLIAAKIAGADECFLIGGAQAVAALAYGTETIRPVDKIVGPGNAYVATAKALVSHIV---GIDSVAGPSEVLIIADETANPKWVAADLLAQAEHDVEATAIAIVTSETLRDQIEQELERQLVQLPRQDIARESLKRGG-VLYRTIEDAIEYANTMAAEHVQLAVKDPEVLMRAIRHGGSFFLGHEAAEAFGDYIAGPNHVLPTSGTARFSSGLSVDDFYRRQTFLEMTELD-ETITKAAIRIAKQEQLEGHARAMAVRME------
>UniRef50_B1YL14(8-405:405) Histidinol dehydrogenase n=1 Tax=Exiguobacterium sibiricum 255-15 RepID=B1YL14_EXIS2  E=1e-145 s/c=1.30 id=41% cov=90%
--------------------------------EQAVRSILEQVANDGDAAVRRYTSEFDRVDLTDFRLDETKIQEAFDQADPNLVDSLKLMATRLVEWHEQELPSDIELVEAD-VTRRQRFVPVDSVGIYVPGGAASYPSTVLMNAIPAKVAGVERVVMVTPvTGLSMEVLVAAKIAGVTEIYTIGGAQAVAALTFGTESIQAVDLIVGPGNRFVAEAKRQVYGIV---GIDSVAGPSEVVVIADETAHPDRIAADLLAQAEHDRDAVAIAFVPTEAMKADVDANIERRLQQLPRQEIARRAMENGGVFVA-SLDDAIEEANRLAAEHLELAVANPQEVVKLIRHAGMIFLGHETPETLGDYVAGTNHVLPTSGTARFASGLSARTFLRHQTMLEATREGVARLANAAKTVARVEGLEAHAQAIEVREN------
>UniRef50_A1ZJE8(1-429:429) Histidinol dehydrogenase n=1 Tax=Microscilla marina ATCC 23134 RepID=A1ZJE8_9SPHI  E=1e-144 s/c=1.20 id=41% cov=92%
-----------------------------EALEKAVRPILRRVQREGDKALRSFVFKYDRVRIKRFQLTPEELAEASNHVSDELKEAINVAKYNIATFHLTQTKAVKKIETTEGVFSWQKNVPIAKVGLYVPStGDAPLYSHILMMGILANIAGCKEIILCSAANhegrIHPIILYTAHLLNIKKVYRVGGVQAIAAMAYGTETIPKVDKIFGPSNEYVSTAKQLVSK--NDVAIDMPVGPSELCYVADQSTNPVYAAADILAHAEQSSHNQLVVLTNAEEVADKIQAEVDKQLNELPlKKEVAKEVFKNAKIIVFKSNVESIAFANEYAPENLVLAIDNAEAVGDRITNASSIHLGHLTPPAVGYYAAGPNHILPSNGFARSYSGLSVDSFVKKINFQQVTPLGLQNVGSTVATMSEAEELLGRKNSIIKRLELLD---
>UniRef50_Q7UX39(62-460:460) Histidinol dehydrogenase n=6 Tax=Planctomycetaceae RepID=HISX_RHOBA   E=1e-144 s/c=1.29 id=39% cov=91%
--------------------------------IEVVETICKDVQSQGTEALLRYTKSLDGAELTAdtLRVPEEDLKAAHAVADPKLIETIGRIRDNIATFQSAILHRDVTITPRPGVSLTQRYVPIPRVGICVPGGAAAYPSTVMMTAIPAQVAGVDEIAVVAPPTpfgaYNTDMLATCHELGIKEVYRCGGAQAVAAMAYGCDALPAVDKIVGPGNLFVALAKKHVFGTVD---IDSFAGPSEVIVIADESANAAFVASDLLAQAEHSPGS-AILITWDESLLTSVQAELSRQLGELERGDLARDALsDFGALVLARDADHACELTDSFAPEHLQIETREPESLIAKIRHSGAAFLGHHTPVALGDYAAGPSHVLPTGGTCRWAAGLSANSFLRSGSVTQFDQSALSAIAQDVITVAEKEGLTAHARSISIRTE------
>UniRef50_B1H0F0(11-402:419) Histidinol dehydrogenase n=1 Tax=uncultured Termite group 1 bacterium phylotype Rs-D17 RepID=B1H0F0_UNCTG  E=1e-142 s/c=1.29 id=38% cov=86%
-----------------------------------VSDIIEDIKNNGDEAVFKYLKKFDNVDLSKkgYRVSQKVIDDAAKRIPKQLKNVIKSSYSNILAYHKYERsqIKKRWNYVKNGLKIGQFYRPVESVGLYVPGGRFPYPSTVIMTAVPAMAAGVKRIVMVTPPKnMNDAVLFSAKLCGIKEIYCIGGVMAVGALAYGTKTLKKVDMIVGPGNAYVNEAKKQVFGRV---GIDSLAGPTEVAIIADKDVPTDYVVADVMAQVEHDPLAKTYLLCESAKKMSEIEKLLPKEALKQLRTELC-------------SLNKAVDIVNNIAPEHLELLVKNYQILLKNVRNAGAVFVGYQTPTASGDYWAGPSHVLPTNGSAKFSSGLSVMTFLKRSAYIEMNKNNKKAYK-TIADFAQAENMQYHKKSAEVR--------
>UniRef50_UPI00017455E1(3-426:428) Histidinol dehydrogenase n=1 Tax=Verrucomicrobium spinosum DSM 4136 RepID=UPI00017455E1  E=1e-141 s/c=1.19 id=39% cov=96%
-----ILRYTDAAYADALCRLNRRA-EASDRVRDVVAAVIADIRQNGDKALLELTQKFDGATLTAeqLVVSTEEVAAAVASLTPEVRAALDASLRNVTTFAHQSLRKDWSMINEQGAEVGEVYHPFERVGVYVPGGTAPLVSTAIMTVAIAAAAGVPEIVVCSPCGKDGKVnanlLAALSLAGATEIYRVGGSQAIAAMAFGTETIKPVTKIFGPGNSYVVEAKRQVFGVV---SVDLLPGPSEVMVLADSSANPAFIAADLLAQAEHGKDSGVAFLTDDETLLNAVVSQVETQGQKLTRQEMVRSVLDKEcFLMLVPTLEEGAEIVNNYAPEHLSLITAREHDILPLIRTAGAIFLGNYSPVAVGDFLAGPSHTLPTGGAGKSFPGLTVDMFQKRTSIVRLSKEACAKSEPIVRVFSEIEGLDAHGLSVSVR--------
>UniRef50_B6A0U7(2-444:448) Histidinol dehydrogenase n=1 Tax=Rhizobium leguminosarum bv. trifolii WSM2304 RepID=B6A0U7_RHILW  E=1e-136 s/c=1.10 id=38% cov=99%
---DTLVSIHTLSAldDAQRKALLQRTESDLSAFIDKVNPIIEAVRIDGDAALADFARQFDKAQVaaDQLRATTEEFSAARASIDPELITTLEFAAGNIRHFHEKQMPETLVLhETHRGVLVGDRWNAIDSVACYVPRGKGSFPSSVLMTAIPAKVAGVRKVVIITPPGpdgtVDPATLVAAEIAGVSDVFKCGGAQAIAAVAFGTQTVPKCDKVVGPGSPWVVAAKKQLSSLIDPGS---PAGPSELIIFSDGSVPAELVALDLCVESEHGPDSSVFFVTDNADFANAVASCVPALWSRMGniRAQYSKTVLSgpRGGIVIARTRADALAFVNDYAPEHLAVLADNAWQYLACFEHAGEILLGPHSAISVANFVLGPSHVLPTGGAAKTTSPLSVFDFLKRTSIASLSKEAYGGFAAHAERLARYEGFDGHANAVsTIRDEALRSAA
>UniRef50_B0S9F2(13-425:430) Histidinol dehydrogenase n=6 Tax=Leptospira RepID=HISX_LEPBA   E=1e-136 s/c=1.18 id=41% cov=93%
-----------------KELYSRFLQGAREDLttaTDRILPILESVRTQGDQALFSYTEMFDGIKLSQLTIDPKKIKT---NVDEKTKEAFLRAKSNIEAFHMEQKRESWS-KVIDGNRLGVKYTPIPSLAVYAPGGKALYPSSVLMGIIPAKIAGVPSIQLITPPQKDgiPEILVwLAQIMDIDRIVTVGGAQGIAAAAYGTESVPKSEFIVGPGNAYVAAAKSYLSGQ-GLIGIESPAGPSEVCIIADENANPKWIACDMLSQAEHGEDSSAILLTTDLTLAKRVSEELEIAFSERPKRLQMKQTaiYENSSILVFPTLDDCIWFSNELAPEHLEIQTKDYESVFAKIEHAGSVFLGPYSPVAMGDYISGTNHILPTARGSRIYSSLGVDTFLKRVTFQEVTKESLENLYPFVKLMSELEGLdEEHGTSVKVR--------
>UniRef50_B2UMH6(8-426:432) Histidinol dehydrogenase n=3 Tax=Verrucomicrobia RepID=B2UMH6_AKKM8   E=1e-135 s/c=1.16 id=39% cov=95%
-----------CFDEMKRRMNRRAL--PEDSVRDTVNAIIRDVSVRGDEALFDYAARFDKAHLdsSSLFVTEAELAEAEAMVEESVKEAIAVSLANIHYFSDRSRRRDWSGVNAQGVEVAERFLPYDRVGIYIPGGKAPLVSTSIMTGGFAQAAGVREIVAATPcgpdGRVNPALLYALKASGATEIVKIGGAQAIAALALGTESVRPVEKIFGPGNRFVVEAKRQL---VGAVAIDLLPGPSEVMVLADDTADAEFLAADLLAQGEHGPDSVVVFVTTSKALLEQVEAEVERQAALLSRGSIIREVLDKHAYgFLVSSIQEGVELVNAFAPEHLVLVTRDEEAVLNGIRTAGAIYAGSLSTVACGDFLAGPSHTLPTGGAGKSFSGLRADQFQRRTSVVRMDRNAVLNSAPYVAEFARVEGLDAHNHSIQVR--------
>UniRef50_UPI0001C3165E(21-420:426) histidinol dehydrogenase n=1 Tax=Conexibacter woesei DSM 14684 RepID=UPI0001C3165E  E=1e-112 s/c=1.02 id=37% cov=91%
---------------------LRRLVPAAASIADPVAAIVADVRDRGDAAVLELTRAHDtgGAEPKALRVSQSELDAALDSLDADVRAGLEVAAQNVGVVAAIGLDDEREVTLGHGQTVRLREVPVRRAAVYVPGGRAPYPSTVLMGVVTAVTAGVEEVVLCSPPGpdgdLNPAILAAAALAGATEVYRMGGAQAIGALAHGTATVAPVDLIVGPGNLWVQEAKRQVSAA-GLVGIDGFAGPSDLMVVLDRGADVRLAALDLRAQAEHGSDSLVLAVSPDG----AALDALSEGLSVVPEPGV-------GALVETASLEDALALANAFAPEHLELIGAGAEALAPEVRNAGCLFVGPGGATAFGDYVAGSNHTLPTDGAARFASGLSARHFRRRMTEVRIPLEAATTLAPAGAAIARAEGFELHAQSMEARM-------
>UniRef50_A3J633(14-136:136) Histidinol dehydrogenase (Fragment) n=1 Tax=Flavobacteria bacterium BAL38 RepID=A3J633_9FLAO  E=5e-35 s/c=1.23 id=44% cov=29%
------------------EICKRPTQTFSD-VEETVKQIFKKVQQKGNKAIAKYTSFFDGVTLENIQVTPEEIELAKKEVATELKKAIQLAKSNIEQFHAAQKTDKIVVETTIGVTCWQEKRPIQKVGLYIPGGTAPLFSTV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q4QN74(1-426:427) Histidinol dehydrogenase n=38 Tax=cellular organisms RepID=HISX_HAEI8  E=1e-170 s/c=1.41 id=64% cov=98%
--MQTII-WNHLSETEKRKVIMRPVQQNGENIQQAVNAIRENVAYNGDRALFELCEKFDGVKLDKLIVSADEIQAASSRISVKLRNAIEQAKTNIEAFHKAQQNQEIDLEIQEGVRCQVVTRPISCVGLYIPGGSAPLFSTVLMLAIPAKIAGCKKIVLCSPPPISDEILYTAHLCGVETIYAIGGAQAVFAMAQGTESVAKVDKIFGPGNAFVTEAKRQVAQ--NSTAIDMPAGPSEVLVIADESADPEFVASDLLSQAEHGADSQVILVATCETLAKETALAIERQLALLPRAETARKALNHSRIFIAESLEQAVEISNEYAPEHLIVQTKNARKLLPYLDNAGSIFLGAYSPESMGDYASGTNHVLPTYGYTKTYSSLGLADFSKRMTVQELTPKGFKNLAETVEVMAEAEQLAAHKMAVSVRLAKLN---
>UniRef50_P62456(14-427:429) Histidinol dehydrogenase n=127 Tax=Bacteria RepID=HISX_BACC1   E=1e-169 s/c=1.44 id=41% cov=95%
----------------KIKLLRENANIIEETVQRNVSEIVRNVRESGDEALSFYTKKFDGVKIKEFRVSEEEEKRASMFVENSFLEALQEAKKNIISYHEKQKRQSMFDCASEGIIRGQIIRPLENVGVYVPGGTASYPSSVLMNVLPAKLAGVKKIVMVTPPregGIDPHILVAASLAGVDEIYTIGGAQAIAALAYGTESIPKVDKIVGPGNLYVALAKREVYGIVN---IDMIAGPSEIVVIADETGNAKYIAADLLSQAEHDERATAICITTNIELAKKVEKEIERQLETLPRSEIARESINrNGAIFIVPSIDEALQLSNEIAPEHLELHIKEPMNALAYVKHAGSIFLGPYAPEPLGDYLAGPNHVLPTSGTARFFSPLSVDDFVKKSSFLSYTEEALRDVQHHIVELANKEGLHAHARAIQIRFEE-----
>UniRef50_B2KCM4(3-426:429) Histidinol dehydrogenase n=1 Tax=Elusimicrobium minutum Pei191 RepID=B2KCM4_ELUMP  E=1e-154 s/c=1.29 id=47% cov=97%
-----IYNYATLTKKEIKALSERSYL-MPEKLKQAVWETGLQVMKRGDKAIKELTAAFDGVTLSSLKVSVKEFKQAEKLVSNELKDAIKTASENIAKFHKSQlKTKEPVIETSKGIECWREFKALGTAGLYVPGGSAPLFSTVLMLAVPAKIAGCKKVYICTPPCknglIAPEILFAAKTAGVDEVYKIGGAQAVFAMAYGTQTVPKADKIFGPGNQYVTQAKMEVSS---FTAIDMPAGPSEVLIIAEESTNASYAAADILSQAEHGPDSQAVLACSSKNKIKEIIAEVDAQLKKLGRKSIAAKALGKSFIMQTRNTKESVEFSNIYAPEHLILNFKDWKKYLTSVQNAGSVFCGTLATESFGDYASGTNHTLPTSGFAKSFGGLNTQSFGKWITYQTVSAQGLRGLGKTVEIMAEAEGLTAHKNAVTIRIE------
>UniRef50_Q3B5E3(26-442:443) Histidinol dehydrogenase n=8 Tax=Chlorobiaceae RepID=HISX_PELLD   E=1e-147 s/c=1.26 id=38% cov=94%
-----------------RDALFRqigRSVDFDPEVQRAVTDILEAVRLRGDMAVLEYTERFQGAVLTSMQVPEEDILRAREEADPAFIRVLEEAWENILRFHRHEVENSFFYEGEGGVVLGQRVTPMDRAMLYVPGGKASYPSSVLMNAAPARVAGVGEIFMTTPcdasGAVSPHILAAASVAGVTSVYRLGGAQAVAAFAYGTQTIPKVDIITGPGNKYVALAKKQVFGHV---AIDSIAGPSEVVVVADDDADAEFITMDLFAQAEHDPDASSVLITPSMRLAEEVRDLAAARVGSMLRGEVIAEALsNNGAIVVVADIEEACRVSDMIAPEHLELHVLHPWELLASIRHAGAVFMGGYSCETVGDYYAGPNHTLPTNGTARFFSPLSVRDFVKHTSIISYTRRQIMACGERIASFADHEGLEAHAEAVRARLKK-----
>UniRef50_B3DXR9(8-425:426) Histidinol dehydrogenase n=1 Tax=Methylacidiphilum infernorum V4 RepID=B3DXR9_METI4  E=1e-144 s/c=1.23 id=36% cov=96%
-----ILRFGDLNWQQEKKGLSRFYLP-SKEIEQTVRRVLEEIIRNGDKAVSLYTEQFDKQSISP---GAFRITEKAPQPPKDVVDALRWAKRNILCFAKANKPKNWSITNREGARVGEYYTPFRRIGVYVPGGTAPLISTALMTVCFAKAAGVKEIVVCSPPPVNPILHFSIIYSGATEIYRIGGIQAIGALAYGTESIPKVEKIFGPGNAYVVEAKRQV---IGPVSIDLLPGPSEIAVFASWPANPEFIAADLLAQAEHGPSSKILFVSPENSLLESVIGAINRQLPSLKRQQILKEVLtDHAYFVQVRSIDEGIGLINDFAPEHLSLQIPGAKKYLAQFKNCGAIYLGPYSAVAAGDFLAGPSHTLPTGGAAKSFSGLTMSHFYRKTSVVEYSKKALCRVSSLLETFARIESLDAHGASITIRKES-----
>UniRef50_B4W8G9(3-434:435) Histidinol dehydrogenase n=2 Tax=Caulobacteraceae RepID=B4W8G9_9CAUL  E=1e-134 s/c=1.11 id=46% cov=98%
-----LIDWSSLDAAGKRAALARPAQRTAGDVTDVVRTILDDVRARGGAAVTDWCLKLDKAPPRRIAITPEAVAEARNALPPGDVRALRMAAENVRVFHQATKPEDTpFIETTPGVRSKLAWRPIASAGLYIPGGTAPLFSSLLMLAIPAGVAGVGERVAVTPPdkngGIHPAMILAAAEAELDAIWLMGGAQAIAALTFGVEledgIIPACDKLFGPGNAYVAEAKKQASALPGGPAVDMPAGPSELMVIVDRDAAPEIAAADLLSQAEHDADAQVILVSTSRATIDYILSEVEVQVAALPREAIARASLNEARAILVRDLDAAAEVANLYGPEHLAIQIDDPEPLVDSIKAAGAVFVGRFAAETLGDYAAGPSHVLPTDGGARTLGGVTTASFMTTMSVQLVSEAGARALAPIAARLARMEGLEAHARAADLRAE------
>UniRef50_A4QA32(1-395:408) Histidinol dehydrogenase n=16 Tax=cellular organisms RepID=A4QA32_CORGB  E=1e-133 s/c=1.21 id=35% cov=89%
--------------------------------------MIADIRARGDEAVREYSLKFDNYGPDSFLVQGEQLQEILDRVPEQVIEDIKFVQDQVRKVAQAQLQSmgEFEIETLPGVHIGQKNVPIDSAGAYVPGGKYPLLASAHMTILTAKVAGVKRVVACTPliqGEVPDATVAAMHLAGADEIYLLGGIQAIAAMAIGTETIKPVSIIAGPGNAFVAEAKRQLFGEV---GIDLLAGPTETLIVADETTDPFIAAVDLLSQAEHGPDSPAVLISTDRAVAEQVIDHINELLPEMPTKDYAEVAWrDWGEVHVVESIEDAFSLADKFASEHVQILTASPRRALDEMKHYGALFLGEGTCVSYGDKVIGTNHVLPTRGAARYTGGLWVGKYVRTITYQEVTNEDSSAfFGELCGRAARVERFEGHARSGDVR--------
>UniRef50_B8E2C3(14-412:417) Histidinol dehydrogenase n=1 Tax=Dictyoglomus turgidum DSM 6724 RepID=B8E2C3_DICTD  E=1e-130 s/c=1.17 id=32% cov=91%
--------------------LLRMEESKVKEVEKEVDFIVEEIRTKGDLALHNFSLKFDNYDSKKygFKISVPEID-----LSNDFATAIKVMIERVKNYYIHEYKNSWFYKDGESI-LGQLIVPVDSVLLYVPGGKASYPSTVVMGLIPAMIAGVKNLYVTTPPSKreDRNLLYTLRLLGIKELYVLGGAHAISAFAYGTESIPKVDMIIGPGNLYVALAKKRVFGDVN---IDGIFGPSEILVWINyrgKDLNLRKIVCDFLAQLEHSPYDRGWMILP-EELLDKVMGLIKEEVEGSGRGDILKEAIKNSFLIIEEDEERAINLINQIAPEHLEIIDFSGERHIPYIKNAGAIFINHSS--IFGDFIAGPSHILPTGGSAKFSSGLSVNSFLKRISFVKLSAKEQKILAEYGSIIAREEGFYMHEKSLR----------
>UniRef50_B5YE85(14-411:416) Histidinol dehydrogenase n=1 Tax=Dictyoglomus thermophilum H-6-12 RepID=B5YE85_DICT6  E=1e-127 s/c=1.15 id=32% cov=88%
------------------------------EIEKNVEFIIEEVKTKGDLALYDFSLRYDNYDSRKygFKINVPDID-----LSTDFAVAIKVMIERVKNYYMHEYKNSWFYKDGESIF-GQLVVPVDSVLLYVPGGRASYPSTVVMGLVPAIIAGVKNLYVTTPPSKrdDKNLLYTLRILGIKELYLLGGAHAISAFAYGTESIPKVDMIIGPGNLYVALAKKKVFGDVN---IDGIFGPSEVLVWVnyDKDLNLRKVVCDFLAQLEHSPYDRGWIIV-SENLVYDLLELIKKEVEDSERGDILKESLKNSFLIIEENEKNAINLINQIGPEHLEIIDPFGERYIPYIKNAGAIFINHSS--IFGDFIAGPSHILPTGGSAKFSSGLSVNSFLKRISFVKLSTQDQKILAKYGSTIAREEGFYMHEKSLR----------
>UniRef50_B1ZNB2(3-429:431) Histidinol dehydrogenase n=3 Tax=Verrucomicrobia RepID=B1ZNB2_OPITP   E=1e-119 s/c=1.01 id=38% cov=91%
------------------------------EITESVAAILADVRERGDEAVVYYAAKFDGAKLraRDLRVKPSDLTVAAKRLPAAERRALVAARDSIMDYNRRGLPRGWTAKNPHGAMVGEKFDPLRRVGLYVPGGQVPLVSTVLMTVTLAKIAQCPQVVVFTPcnaeGKIADGLLAALHLLGVDEVYRVGGVQAIGAMAFGTTTIPPVDKIFGPGNAYTCEAMRQVFGIV---GVNGLPGPSELMVIADDTARADYAAADLLAQAEHGSGrEKVYLVATSSRVITEIVNEMNGQLQTLTRSEKTQRVLEQGFLaIEVGSMQQAAAVANYVAPEHLELLVSEAavKQLTKAVTTAGAIMIGNETPTALGDFTAGPSHVLPTGRAGRFFSGMRVSDFLRRTSLVRYDRKSVRKGAPVVAAFAAMERLDAHGRSVKIR--------
>UniRef50_B4CYY3(4-140:162) NAD+ oxidoreductase n=1 Tax=Chthoniobacter flavus Ellin428 RepID=B4CYY3_9BACT  E=5e-29 s/c=0.96 id=33% cov=28%
--------------------LKRSAEAH-PQVRKTVQDVLEAIRTEGDSALLEFTERFGGPRLTAkqLRVTGK------PKVDAETKEAVATAHANVLAFARKSLRENWTMKNAQGGLVGERFDPFKRVGIYVPGGTAPLVSTAVMTVTP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_P59398(7-433:435) Histidinol dehydrogenase n=5 Tax=Buchnera aphidicola RepID=HISX_BUCBP  E=1e-168 s/c=1.39 id=50% cov=99%
-----IIYWKSCSEKEKREILFRPVVNDNSQIKEVVKEIITNVKNSGDKALYDYTKTFDKIRLESIQVSYGEIVDSDSFVNEEIQKSISVAKNNIKIFHEKQTHNVVNIEIQPGVFCRQIIRPIQSVGLYIPGGCAPLVSTVLMLAIPAKIVGCKNIILCSPPPITKEILYASKICGIHNIFQVGGAQAIAAMAFGTKTIPKVNKIFGPGNVYVTEAKLQINALLNDLSIDMLAGPSEILIIADFKANACIIASDFLSQMEHGIYSQAILVTPSYDLACNVIFEINIQLKNLSRKKVINKSLKYSRIIVTKTLLECFEISNLYAPEHLIIQCENSNRLLVYVINAGSIFLGRWSAVASGDYVTGTNHVLPTYGSAIVNSGLTVMDFQKIISVQKLDQQGLIDVSSSIISLSEVERMDAHTNSIKQRLIALQD--
>UniRef50_P59399(9-425:428) Histidinol dehydrogenase n=14 Tax=Bacteria RepID=HISX_LACPL   E=1e-161 s/c=1.36 id=42% cov=95%
-------------ASLKRLVQTKTQQLTDLKVESAVREIIANVIKNGDAAVKDYETQFDKVTLTDFKLSQTVIDDAYNNLDPQVKDALLLAKRNITSFHEKEKATGFIDAEQPGVLRGQKLMPLNRVGLYVPGGTAAYPSTLLMSALPAKIAGVNEVIMVTPPqvdGINPAVLAAAKIAGVDAIYQVGGAQAIAALAYGTESIPAVDKIIGPGNIFVATAKKQVFGQV---AIDMVAGPSEIGILADDSADPRQLAADLLSQAEHDRRARPILITDSADLAQAVSDNVTSQLKVLPREAIATDAVNeKGFIAVVAKIEEMFDLMNTVAPEHLEVQLKNPTQYLNLIKNAGSVFLGRYASEPLGDYVAGPNHILPTSGTARFSSPLGVYDFVKRTSFIQYTKDALAKEAPAITTLARVEGLEGHARAIESRFDT-----
>UniRef50_Q3AR25(8-428:428) Histidinol dehydrogenase n=13 Tax=Bacteria RepID=HISX_CHLCH   E=1e-154 s/c=1.30 id=37% cov=92%
-----------------------------EAAHKAVDEILAKVRQQGDRAVLNYTEQFQGVRLTSMQVDEEAIEMAYRHADPSLIATLHEAYANIVRFHEHEVERSFFYEAEGGVLLGQRVRPMERAMLYVPGGKAAYPSSLLMNAAPAKVAGVCEIAVTTPcdatGVVNPTILAAAKVAGISSIYKIGGAQAVAAFAYGTESIPKVDIITGPGNKYVALAKKQVFGHV---AIDSIAGPSEVVIIADESAHAEFVALDMFAQAEHDPDASAVLITTSESFAQAVQQAVASLLPTMLRHEtIASSLLHNGAMVLVPSLDDACAVSDMLAPEHLELHVVQPWDILPKLKHAGAIFMGSYSCETIGDYFAGPNHTLPTSGTARFFSPLSVRDFVKHTSIISYSPEQLRSKGAQIAAFADAEGLQAHAEAVRVRLKTL----
>UniRef50_Q5ZW87(1-431:431) Histidinol dehydrogenase n=6 Tax=Legionella RepID=HISX_LEGPH   E=1e-153 s/c=1.26 id=45% cov=98%
----TIKNWQLLSENDKKLCLSRPRQ--SSAIKENVLEIINQVQLSGDKALYDLTKQFDRVNLQYLQVPQEKIEQA--NIPKNALNAITQAIGTISSYHQSLLPENTEISTASGITIRNVYRPIQKVGLYVPGGnKTPLVSSLLMQAIPAKVAGCPIKVLCTPPdaegEINEHILVAARLCGIDTIYAIGGAQAIAAMAYGTESVIKVDKIFGPGNSYVTQAKTLVAIDADGAAIDMPAGPSEVMILADTEANPEFIAADLLAQAEHGPDSQVILICDECELANQVNQQLEIQMSYLSRIEFIKRSLANSRIIICSNQSEQLDIINSYAPEHLIINRKNPEPWVEKIVAAGTVFLGSWAAETMGDYVTGSNHVLPTSGFARNHSGLSTLDFMTRFTVQAINQEAIRNLGPAAMTLAELEGLDAHANAVQIRLNTLGD--
>UniRef50_Q4FQF8(4-431:431) Histidinol dehydrogenase n=6 Tax=Proteobacteria RepID=HISX_PSYA2   E=1e-149 s/c=1.24 id=43% cov=91%
-----------------------------ATLLTTVDDIIARVRHGGDSVVLELTQQFDQhpaTTTQALELSKEALAEAFANLDDVVKSALITAATRVKTFHERQVQETWQYEDELGNRLGQKVTALDRVGIYVPGGLASYPSSVLMNAIPAKVAGVKEVIMVVPAPKgvlNPLVLAAAHLAKVDRVFTIGGAQAVAALAYGTETIPAVDKITGPGNKYVAAAKRAVFGQV---GIDMIAGPSEVLVYAEGEAqdRADWLAMDLLSQAEHDRIAQAIFVTTSAQQLKEVAIEIEKALAELPKADIARDSLKNrGVLILVRDREEGMAVINRVAPEHLELSVDHPDALLNSIRHAGAIFMGRHTPEAIGDYCAGPNHVLPTSGTARFSSPLGVYDFQKKSSIIYCSESGSKPLAQTADILAQHEDLEAHARSARYR--------
>UniRef50_Q9P777(11-435:439) Histidinol dehydrogenase n=71 Tax=cellular organisms RepID=HISX_SCHPO  E=1e-149 s/c=1.25 id=47% cov=96%
----------ALTAEERTRLLARPIQN-TQKIRTIVQPIIEDVKSRGEASLIDYASKFEKVQLKS-AVLKAPFDDDLMKISPMIKEDIDIAFNNIFAFHSSQLRPTIAVQTMRGVVCQRMSRPINRVGLYIPGGTAVLPSTALMLGVPAKVAGCPHVVISTPvrkdGTVAPEIVYIANKIGAEAIILAGGAQAIAAMAYGISGVPKVNKIFGPGNQFVTAAKMHVQNDYGAlVAIDLPAGPSEVLVIADETCNPESVALDLLSQAEHGLDSQIILLTVslSPEMFDRIQKAINDHALRLSRSYIIKHAIKKSVIVQVDNVDQAFEWSNLYGPEHLVLHLKNASSYIPKIDNAGSVFVGPWSPVSMGDYASGTNHTLPTYGYASSYSGVSTDSFLKYITTQELTEEGIQRLGPTVIRLAELEGLTAHADAVRVR--------
>UniRef50_A3EUM9(24-442:445) Histidinol dehydrogenase n=3 Tax=Leptospirillum RepID=A3EUM9_9BACT   E=1e-145 s/c=1.23 id=38% cov=95%
-------------------IFQRGRDSEGETLRARVSSILGDIRREGDVALLRYARELDGFrgELKDLRVSPGRMEESFGALPSEIRKALVFAKDRIEEFHGALREKGLSGLASRPGKGGVLVRPLHRVGVYVPGGTAAYPSTVLMTAVVAKVAGVKQIVGVSpagPGGIPDAILAAFHVCGVQDVYQVGGVHAIAAMAYGTGTIPRVDKIVGPGNRYVAEAKRQVFGDVD---IDMVAGPTEILILADDSARPEWLAADMIAQAEHDTRASAVLILTDMTLAKAVVLALERQISSLPRQKIAEESlLKYGFILVVPSVQVAVEISDLVAPEHLELQVRNPEKWLGLIQNAGAVFLGSEMAEAFGDYCFGPSHVLPTNGSARFSSPVSIETFTKRTSLLEgfRSRQELEDVVRNSALLARLEGLEGHARSALARLENVQKE-
>UniRef50_UPI00016BFCCC(17-419:419) histidinol dehydrogenase n=1 Tax=Epulopiscium sp. 'N.t. morphotype B' RepID=UPI00016BFCCC  E=1e-143 s/c=1.26 id=43% cov=91%
----------------------------SPQIERDAQEIVETVKRLGDQALFDYALKFDRAQLTSLLVSEQELKDAYEXIDDDLLGVIRRAKKNIEDFHKRQITNSFMVE-KDGIIMGQRVTPIERVGIYIPGGXAVYPSSVLMNVIPAKLAGCSYISVVTPPredgTVAKEILAICAMLGVDQVFKIGGAGAIAALAYGTESVLPVYKITGPGNAYVAAAKKAVFGKV---GIDMIAGPSEILIIADEKQXPKIIAADMLSQAEHDMLARAILLTTSKEIAEEVATEIEIQLSKLPKEKIARPSIdDNGLIVVCDTLSECFAISNDLAPEHLEIMLDNAISYLPEIKNAGSVFLGRYTPEAVGDYYAGVNHTLPTNQTSKFSSALSVDTFVKKSTFVQYTEEMLQKYKDDIVLFAKHEGLDAHARSVQSRFQ------
>UniRef50_Q5WIU9(20-421:424) Histidinol dehydrogenase 1 n=52 Tax=cellular organisms RepID=HISX1_BACSK  E=1e-139 s/c=1.24 id=37% cov=91%
-------------------------------VEQTVASLIARIEKEGETAVRELSRQFDNWDPEQFRLSAEEIEKIVRSVPDQVKADICFAQEQIRHFAEQQRasIQDIEVETRPGVFLGHKNIPVNSVGCYIPGGRYPMVASSHMSILTAKVAGVKRVIGCTPPingEIPAATVTAMHFAGADEIYILGGVQAMTAMAVGTETIEAVDMLVGPGNAFVAEAKRQLFGRV---GIDLFAGPTEVLIIADDTADGEMVATDLLGQAEHGPTSPAALITTSKKLAEETVAEIERQLQTLPTADVAKVAWeEHGMIILVDDLAEAVVEADKLAYEHVQVLTENPNYFLDHMTNYGALFLGPETNVAYGDKVIGTNHTLPTKKAAKYTGGLWVGKFLKNCTYQRCTPEASAEIGRIAERLCELEGFIGHKAQASLRVKR-----
>UniRef50_D0XPF3(9-437:440) Histidinol dehydrogenase n=1 Tax=Brevundimonas subvibrioides ATCC 15264 RepID=D0XPF3_9CAUL  E=1e-135 s/c=1.13 id=42% cov=97%
------IDWASLDGQGRFDALARPSRRSERDVQDVVSGIFEQVALSGGLAVTQFAERIDGFKPRRIAITPEAVAAARDALPPADTRALRVAAENVRVFHQATKPEDTaFVETTPGVKSKLVWRPIGAAGIYVPGGTAPLFSSLLMQAIPAEVAGVTTRVVVTPPakdgSVHPAMILAAAEANLDAIWLIGGAQAIAALTYGAvlddGEIPACDKLFGPGNAYVAEAKRYAAALPNGPSVDMPAGPSELLVIADRFCDPEIAAADLLSQAEHDADAQVILVCERAATIDAILAEVEEQLTTLPRADIARASLSEARAILVSDMAEACAVSNLYGPEHLAIQAEDAEALVASIRAAGAVFVGRWAAETLGDYAAGPSHVLPTDGGARTLGGITTASFMTSMSVQTVTEAGAERLGPIAARLARLEGLEAHARAADLR--------
>UniRef50_Q5JFR5(4-375:376) Histidinol dehydrogenase n=9 Tax=cellular organisms RepID=HISX_PYRKO  E=1e-133 s/c=1.28 id=41% cov=84%
-----------------------------------VREILEDIRRRGLEALREYSERFDNYS-GPFRVSEGEFEEAEELVPEEDKRVIEETMERLWEYHARQ-FRDVELYIKRGSLYGLIYRPIGRIGIYVPGGK-PLPSTLMMVGIPARIAGVREIAVTTPPkdgKVNPYVLYVAKLLGIEEVYKLGGVGAIAAMAYGV-GMRRVDKIFGPGNRFVNEAKRQVFGIV---GIDSLAGPSEIAVIADESADKDYVLADLLSQLEHGKDSKAWLLTTSRELAD-----------YCSREGI--------EVLLCRNLEECAEKANEIAPEHLEIITENPEELVDLIENAGAIYLGPYTPVPAADYFLGVNHVLPTGGAARFSGVLTVMDFMKPITLARVSREEFLAYRRLGMRLAEIEGMEAHRRSLEVR--------
>UniRef50_C1FAE2(14-422:428) Histidinol dehydrogenase n=1 Tax=Acidobacterium capsulatum ATCC 51196 RepID=C1FAE2_ACIC5  E=1e-133 s/c=1.17 id=41% cov=92%
--------------------LLTGSEASYERALPAAQRIVQGVRRGGDAALLRYRAKFDGiAASEPLRIPAEEMEAAWKATTAELKAALKQAAKNIRRFAQKQRPRDFTLQMAPGVTAGQKVIPLEAVGCYVPSGRYPLPSTLLMTAIPAQVAGVRRIVAVSPRP-AKETLAAAHMLGVAEFYRIGGAQAVAALAYGTASIERVGKIVGPGNAYVTAAKKAVSFD---CGIDMLAGPTEI-VIASENGTVEGIAADLVAQAEHDPDAIAILVTSNAALGRAVAAKTKLRAQS---NAIAKQSIaANGAVILTRDVEEARMLTNQLAAEHL---TVDSSADLAWVRNAGSVFVGRWSSQPLGDYVSGPNHTLPTSGLARLRGGLSVMDYLKLVTVQEYSATGVRQLGPSAVALAEAEGLVGHADAVRVRLQSAK---
>UniRef50_D1B7M0(8-420:424) Histidinol dehydrogenase n=2 Tax=Bacteria RepID=D1B7M0_THEAS   E=1e-130 s/c=1.14 id=41% cov=90%
-------------------------------VSHEVRRIIDWVVLHGDRAVLEGSRLHDRSSRDSILVPVEELQRAHRSMDPELLEAVRYAASNVETFAQRQKgalMPLEESEVRDGVYLGHRVVPVDSCGIYIPGGSYPLISTAVMLAVPARVAGVGRICACTPvrrgtNSPDPSVLGTLYELGVTEVYAAGGAYAVAAMAHGTESIPPVDVIVGPGNKYVTEAKRQCFGKV---GIDFVAGPSEVLIIAQEG-DPDFIAWDLLAQAEHDPDAKGVLVTTSPALARQVMDRVETILGEIVTSPVARSSWeDHGEVLAAEGMDEAVEFSNRMAPEHLELMVQDPDRWIPRLRNYGALFIGEHSAEVFGDYASGSNHTLPTAGASRYTGGLWVGTFLKVLTSQRVTREGARELARVSALLAQAEGLMAHRGAALAR--------
>UniRef50_C1A4M1(12-437:816) Histidinol dehydrogenase n=1 Tax=Gemmatimonas aurantiaca T-27 RepID=C1A4M1_GEMAT  E=1e-120 s/c=1.02 id=37% cov=95%
--------WDRLDNATRRALEDR-ASTVDPTIRERTSAVIDAVRRTGDAALIDMARRFDGATLETLEVPRAEWDRALAALDPALRQSLERAARNIATVHRAFLPTITRSTPEPGITVVRRPDPLGRVGIYAPGGRAAYPSSLLMGAVPARVAGVGEIIVCTPPGPDGrpadVVLAAAALANVDRVFAVGGAGAIAAMALGTASVPRVDRIMGPGNAYVAEAKLQL---VSAVAIDAPAGPSELLVLADASADANTIAREMLAQAEHDPDAAVLAVivdhSATSSLATRVETALQTQLASAPRADVMRAALGaRGGVVHMTSMDEAITFANRWAAEHLLLLVDDTqrDRVLAALRNAGTIFVGASSSVAFGDYMTGANHVLPTAGAARSYSGLSTLDFVRWTTWQEVTPAAAASLSADVGRFADAEGLPAHAATAR----------
>UniRef50_B9NIZ3(134-385:394) Histidinol dehydrogenase n=1 Tax=Populus trichocarpa RepID=B9NIZ3_POPTR  E=8e-89 s/c=1.31 id=46% cov=56%
-----------------------------AAIEQRVADILADVQKRGDAAVLEYTARFDGLQVEgmaALELTQAELKAAFDSLGDEQRDALTAAAQRVRTYHEAQKRasgESWSYRDADGTLLGQKVTPLDRVGIYVPGGKAAYPSSVLMNAIPAHVAGVQEIIMVVPTPrgeKNALVLAAAYVAGVTRGFTIGGAQAVAALAYGTATIPKVDKITGPGNAYVASAKKRVFGTV---GIDMIAGPSEILVLADGSTPPDWVAMDLFSQAEHDELAQSILLC------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q5E638(1-429:439) Histidinol dehydrogenase n=29 Tax=Bacteria RepID=HISX_VIBF1   E=1e-178 s/c=1.46 id=65% cov=98%
--------WQSLSDSQQDTVLQRPAITEGANITAAVTSVINTVKQEGDAGVFALTEKFDGVKPDSIRVSNAEIEAASDRLSEEMKTALKQAYSNISKFHQAQKPQPVKVETQPGVICEQITMPINKVGLYIPGGSAPLPSTVLMLGIPAQIAGCHKVVLCSPPPIADEILYVAKLCKIDEVYNIGGAQAVAAMAYGTESVSKVDKIFGPGNAYVTEAKRQVSNDFRGAAIDMPAGPSEVLVIADESADPDFIAADLLSQAEHGPDSQVVLVTPSPIIADQVADAVERQLKELSREDIARQALGSSLLIVADSLTQCVSISNFYGPEHLIVQTKNPRELLPLLDNAGSIFLGDYSPESAGDYASGTNHVLPTYGYTRTYSSLGLADFSKRMTVQELTADGLKGLAPTVVTMAEAEGLDAHKRAVTIRIEKLAQ--
>UniRef50_Q58851(30-429:429) Histidinol dehydrogenase n=16 Tax=Euryarchaeota RepID=HISX_METJA   E=1e-164 s/c=1.45 id=44% cov=91%
-----------------------------EEILPTVMEILKDVKEKGDEALKYYTKKFDGVEIEDFKVTDEEIEEAYNSVDYKVVEAIERAKENIYFFHKKQMEQIKDLNVEnNGIILGQVVRAIEKVGCYVPGGRAFYPSTVLMTTIPAKVAGCEEIYITSPPTKdgkgNPATLIAGDIVGVSAIYKVGGVQAIGALAYGTETIPKVDIIVGPGNIYVTTAKKMVYGEV---AIDFLAGPSEVLIIADETANAEFVALDFIAQAEHDPNASCVITTTSEKKAEEIKNKIFEEIEKAERKEIILKALENSAILI-GDLEECIEFSNKYAPEHLEILTKNPEEVLNKIKHAGSVFLGEYSPVPVGDYASGTNHVLPTSQFARMSSGLNVETFLKKITYQKLDKESLKNIADIVITLAEAEGLFGHAEAVRRRLK------
>UniRef50_Q46J19(18-447:449) Histidinol dehydrogenase n=60 Tax=Bacteria RepID=HISX_PROMT   E=1e-163 s/c=1.34 id=39% cov=97%
----TIKTANSIDQAqfELRKITERTSGTVQDEAIKVVDDILKNVRERGDEALTEYTSRFDGFLTEKFQVSSDLILKAWEETPRELQDSLLLAKKRIEKFHSLQVPKNITYTGPNGETLGRRWSPVEKAGIYVPGGRAAYPSTVLMNAIPAYVAGVNQIIMVSPANsqgeINQTVLAAAHITGINKIFRLGGAQAICALASGTESIPKVDVITGPGNIYVTLAKKKVYGKV---GIDSLAGPSEILIIADQSAKLEHVASDMLAQSEHDPLASAILITTNTKLAEKLPAEINRQLINHPRLKICQESIsNWGLIVLCDDLETCAQLSDTFAPEHLELLVEDPKKLSESINNAGAIFMGPWSPEAIGDYLGGPNHTLPTSGTARFAGALGVETFMKNTSLIDFSKEAFNENKNAVVQLANSEGLHSHAESIRIRDSK-----
>UniRef50_Q30TA4(8-428:430) Histidinol dehydrogenase n=16 Tax=Epsilonproteobacteria RepID=HISX_SULDN  E=1e-162 s/c=1.37 id=40% cov=96%
---------NSSFKAEFKELLERGKMDIAH-VSATVGTIIDEIKSNKNQALKEHITKFDKWTPvsdEDLKISTESMSRAYENLDKALKAALHLSYDRIKAYHEKQKPRSWFDDEPNGTILGQRVTPVDSAGLYIPGGKAAYPSSLLMNVIPAQVAGVQNIVVCTPTPEnepNELLLAACHLCGVSEVYKVGGASAIAAMAYGTETIPKVDVITGPGNIFVATAKKMVFGDVN---IDMIAGPSEIGILADDSANPSHMAVDMLSQAEHDEMASSILITPSQKLADAIKAEIENWLKILPRQKIARESIEKrGAIIVTSDMQEAIDLMNEIAPEHLEVATLSPFELLPLIKHAGAIFLGHNTPEAVGDYMAGPNHTLPTGGTAKFFSPLGVENFMKKTSIISFSAKAINEIGEECALIAKIEGLTAHEQSIRVRL-------
>UniRef50_Q02136(12-431:431) Histidinol dehydrogenase n=9 Tax=Bacteria RepID=HISX_LACLA   E=1e-162 s/c=1.37 id=40% cov=93%
--------------------------EVSKEVNKTVQQIVADIQKNGDTALFNYAKKFDGydVNTSNLLVTRMEREAGLEQIDEDYFRILRRTKSQIEEFHKHQLGNSWNIFKENGVIMGQIARPLERVALYVPGGTAAYPSTVIMNAVPALLAGVKEIIMITPvkadGKVNPNILAAAEVCGIETIYKVGGAQGVAAVAYGTESIPKVDKIVGPGNIFVATAKKICYGVVD---IDMIAGPSEVLVIADKTAKPKYIAADLMAQAEHDKLASAILVTTSEKLVQQVDEELNRQVQNLERREIIESSIrNYGGAIVVKNIDDAFDVSNQLAPEHLEVLTSEPLTQLPKIKNAGSIFIGEYTPEPLGDYMSGSNHVLPTGGTAKFYSGLGVYNFIKYLTYSYYPKEVLADFKEDVETFAKSEGLTAHANSISVRFDEM----
>UniRef50_Q9C5U8(35-463:466) Histidinol dehydrogenase, chloroplastic n=34 Tax=cellular organisms RepID=HISX_ARATH  E=1e-162 s/c=1.34 id=49% cov=97%
---------SELSSSQVDSLKSRPRIDFS-SIFATVNPIIDAVRSNGDNAVKEYTERFDKVQLNKVVEDMSEL--SVPELDSNVKEAFDVAYDNIYAFHLAQKSTEKSVENMKGVRCKRVSRSIGSVGLYVPGGTAVLPSTALMLAIPAQIAGCKTVVLATPPSKDGsickEVLYCAKRAGVTHILKAGGAQAIAAMAWGTDSCPKVEKIFGPGNQYVTAAKMILQNSEAMVSIDMPAGPSEVLVIADEHASPVYIAADLLSQAEHGPDSQVVLVVVGDSVdLNAIEEEIAKQCKSLPRGEFASKALSHSFTVFARDMIEAISFSNLYAPEHLIINVKDAEKWEGLIENAGSVFIGPWTPESVGDYASGTNHVLPTYGYARMYSGVSLDSFLKFMTVQSLTEEGLRNLGPYVATMAEIEGLDAHKRAVTLRLKDIEAK-
>UniRef50_C0GFZ9(2-429:432) Histidinol dehydrogenase n=1 Tax=Dethiobacter alkaliphilus AHT 1 RepID=C0GFZ9_9FIRM  E=1e-161 s/c=1.33 id=44% cov=95%
-----------------RETFTRAGFDDYPEATQAVRDILAEVNQRGDEAVLEYTRKFDGVELETLLVSEEEFAAAEEAVDPEVRQSLVEAAENIRDFHRRQVQNSWLEHQADGVALGQRVTAVEKAGAYVPGGGAAYPSSVLMTVIPARVAGVEKVVLVTPPQaggeINPYTLVAAKIAGADAVYKCGGAQAVAALAYGTETVPKVDKIVGPGNLYVTLAKREVSGMV---GIDMLAGPSEVLVVADASARADFVAADLLSQAEHDVMAASYCVTTSARLALDLQKELKRQCAQLERCDVARESLqQQGALVIVDSLDEALEIVNELAPEHLELQLSEPWEALGKVKNAGAVFVGPYTPEPVGDYWAGPNHVLPTAGAGRFSSVLSVDDFVKKTSVIYYSPQALLKSAQKIEGLARVEGLTAHGQAVKIRREYLEEK-
>UniRef50_D1CF70(10-432:433) Histidinol dehydrogenase n=1 Tax=Thermobaculum terrenum ATCC BAA-798 RepID=D1CF70_THET1  E=1e-161 s/c=1.35 id=45% cov=96%
----------DLSPEERRRLTHRSG-AISMDVTSVVRQIVEDVRQKGDESVREYTERFDGVKLDSLEVPRVEIETALDRIDQHLAEAMSIAASNIRAFHSAQIHPEPVVETSPGVKVWRVWRPIERVGVYVPGGGARYPSTVLMHAVPASVAGCSEIVLCTPPgpdgKVPEATLAAAALSGVTRVFSIGGAQAIAAMAYGTQTIPPVQKIFGPGNVYVTAAKMLVFGDVD---IDKPAGPSELVIIADDTADPRETAADLIAQSEHAPDNASVLVTTSESLAEAVLSELTRQLEDLPNRDRVISSFrSNGFILLVEDLAQAVGFVNEYAPEHLQIVTVSPREILEGINNAGSIFLGRYSPVPAGDYAVGSNHVLPTSGSARTFGPLSTEEFGKWVQVQELTQEGLRSISNAVTAMARAENLEGHARAIEVRFS------
>UniRef50_Q4ZNV9(10-434:448) Histidinol dehydrogenase n=116 Tax=Bacteria RepID=HISX_PSEU2   E=1e-159 s/c=1.33 id=41% cov=92%
---------------------------SDDSVNQRVLDIIKAVRERGDAALVEFTQKFDGlqvASMADLILPRERLELALTRITPGQREALEKAAERVRSYHEKQKQDSWSYTEADGTVLGQKVTPLDRAGLYVPGGKASYPSSVLMNAIPAKVAGVTEVVMVVPTPrgeINELVLAAACIAGVDRVFTIGGAQAVAALAYGTESVPKVDKVVGPGNIYVATAKRHVFGQV---GIDMIAGPSEILVVCDGQTDPDWIAMDLFSQAEHDEDAQAILVSPDAEFLDKVAASITRLLPTMERAAIVETSINgRGALIKVADMAQAIEVANRIAPEHLELSVADPEAWLPQIRHAGAIFMGRHTSEALGDYCAGPNHVLPTSGTARFSSPLGVYDFQKRSSIIYCSPQGASELGKTASVLARGESLSGHARSAEYRI-------
>UniRef50_D0JBA3(3-430:435) Histidinol dehydrogenase n=2 Tax=Blattabacterium RepID=D0JBA3_BLASB   E=1e-157 s/c=1.30 id=45% cov=94%
-------------------ILNRSSEKISH-LTDLVLSIINNVKNNGDTAVKTYTRKYDHVDIKHIQVTEEDFQKANMKVSSHLRKSIEIAYKNIECFHKKQIHEESKIEVSTGVFCWRKSVPIEKVGFYIPGGSAPLLSTVLMLGVPGKLAGCKNIVLCSPPNkngeIHPSVLYTAKYVGINQIYKVGGVQAIAAMAYGTESIPSVYKIFGPGNCYVTIAKQIVSQK-GIVSIDMPAGPSEVVIMADDEANPKYVASDLLSQSEHDPESYILLVTiNNKSWIEKVKEELKKQFYHLSKKKILLKIFRKSKIVVFSSLEECMNFINQVAPEHLIINCNNVSYWSEKVINAGSVFLGNYSPVSIGDYASGTNHVLPTYGYAKSYSGVSVDSFVKKITFQKISKKGLQNLSECVNVLSSEEGLIAHKKSIDIRLK------
>UniRef50_C9KKX1(48-445:447) Histidinol dehydrogenase n=1 Tax=Mitsuokella multacida DSM 20544 RepID=C9KKX1_9FIRM  E=1e-156 s/c=1.39 id=40% cov=90%
-----------------------------------VRQIVGDVRREGDAAVIRYTHLIDRVDykPEDFLVTEAEYEAAEKAADPAVVESLRKAAENVRRYHQEQKPNSWMTYREKGSILGQSIIPLDRVGIYVPGGTAAYPSSVIMNAVPASVAGVGEIIMMVPPkngKINPYVLIAARAAGVKKIYKIGGAQAIAAMAFGTETIPRVDKITGPGNIFVTLAKKEVYGHVD---IDMLAGPSEILIVADKTADPVYTAADMLSQAEHDPLASSIVITDDAELAEKVAKEAEKQLAALPRREIAQASIDRNGLIVVaDDMMQAMRFANVSAPEHMELLTAQPFQLLPYVRHAGAVFLGAYSPEPLGDYFAGPNHVLPTGGTARYYSVLNVETFMKRTSIISYTQPALSDVSEDIIRLAETEGLQAHANAIRIRRE------
>UniRef50_Q2PPB3(456-878:881) Histidine biosynthesis trifunctional protein n=12 Tax=Phaeosphaeria RepID=Q2PPB3_PHANO  E=1e-154 s/c=1.29 id=48% cov=95%
-----------------AAALQRPSQKSTGKIIGICRPIIDAVKTRGDAALLEYTHKFEKATSLTSPVLRAPFPPELMQLAPETAKAIDVSFENIRKFHAAQReEKPLVVETMPGVVCSRFARPIERVGLYVPGGTAVLPSTALMLGVPAMVAGCKKIVLATPPrsngKVTPEVVYAAHKVGAEMIVLAGGAQAVAAMAYGTESVSKVDKILGPGNQFVTAAKMHVSNDTNaGVSIDMPAGPSELLVIADASANPAFVASDLLSQAEHGVDSQVILIAVglNEAQLTAIEDELHKQANALPRVDIVRGAIEHSLTLAASTIEEALELSNQYAPEHLILQVANADKVVELVENAGSVFIGEWTPESVGDYSAGVNHSLPTYGYAKQYSGVNLASYVKHITSAHLTKEGLQNVGPAVMELARVEELEAHRRAVSLRL-------
>UniRef50_Q3J079(5-433:434) Histidinol dehydrogenase 1 n=26 Tax=Proteobacteria RepID=HISX1_RHOS4  E=1e-152 s/c=1.26 id=41% cov=96%
--------------EADFTALLGMKREDSPDVDAVVAGIIADVRARGDAAVIELTARFDRLELTPERLafSEAEIEAEIATVSAEDRAALELAAERIRAYHARQMPENARWTDAAGAELGWRWGPIASAGLYVPGGLASYPSSVLMNAIPARVAGVERLVVACPTPggvVNPLVLLAARLAGVDAVYRIGGAQAVAALAYGTETIRPVDKITGPGNAYVAAAKRRVFGRV---GIDMIAGPSEILVIAEGAVDPDWIALDLLSQAEHDESAQSILVTPDEALGRAVVQAVEARLETLERRAIAGASWrDYGAVIVTRDLEEAAALSDRVAPEHLELCVADPEALAARIRHAGAIFLGGWTPEAIGDYVGGPNHVLPTARSARFSSGLSVMDFLKRTTLARMTPAALRAVGPAAERLAISESLEAHGLSVRARLDRLNE--
>UniRef50_Q9X0D1(4-428:428) Histidinol dehydrogenase n=6 Tax=Thermotogaceae RepID=HISX_THEMA   E=1e-151 s/c=1.26 id=37% cov=95%
-------------DKEVLRLLKQRMESVS-QVEETVKEIIRRVKEEGDRALEEFLKRFEKhpVGIENLRVTEKEISEA--QVEEEFVETIKIVIEDLKEFHRRQEERSFFFTTKGGSFLGEMVVPLESVGIYVPGGKVPYFSTLLMCAVPAIVAGVERIAVTTPPnengGISPYILKTCEILGLKEIYRMGGAHAVAALTYGTETVKPVDKIVGPGGVFVTLAKKHVYGDV---GIDSIAGPSEIAIVTDGSADLDLIAADFLSQAEHDENAMSVVITTSKEVFEKLPQVIERHLEALPeeRRKTARISTENfGTIILTDSLKRAFEISNLIAPEHLEVLVENPFEPLGHIKNAGSVFLGKYTCESVGDYGAGPNHVLPTFRSARFSSGLRVSDFTKKIFITHLSEEDFRRKSELYSKMARWEGFEAHARAIDVRREKL----
>UniRef50_P62457(26-432:436) Histidinol dehydrogenase n=27 Tax=cellular organisms RepID=HISX_DESVH  E=1e-150 s/c=1.31 id=43% cov=91%
-----------------------------DAVEPVVRDILAAVRSKGDEALAEYTRRFDCPDFTPalLHVTSEEVAQAVASVPADDIAIIRQAADNIRSFHEAQKERSWFVTHDDGTILGQKVTPVDRAGLYVPGGKGgdtPLLSSLLMNAIPAQVAGVTSITVASPPrpdgTLNPHLLAAAHILGITDIIRAGSAWAVAAFAFGTQTIAPVDVIAGPGNIFVTTAKRMVQGRV---AIDMIAGPSEILILADATARPDWVAADMLSQAEHDPLASSILVTTEPALAEAVTAELERQLATLPRADIARKALaDWGAVVVVPDMDVAVAIANRVAPEHLEVLTAQPWELAGSLRHAGALFLGPYSPEPLGDYFAGPNHVLPTMGTARFSSALSVQTFCKRTSIIAASRAFAERNADAVARLARLEGLEAHARSAASR--------
>UniRef50_Q3ZXL7(24-436:436) Histidinol dehydrogenase n=5 Tax=Dehalococcoides RepID=HISX_DEHSC   E=1e-150 s/c=1.29 id=39% cov=94%
-----------LDETERTELARRLGVDP----EKAVNGIIADVRKQGDEAVLGYTLKFDRANLSKLEVGQPEIQQAASEIPAELFEALQLAASQIRAYHRFQKEAVW--KTAEIMQGKQLIRPLERVGLYVPGGKAFYPSTVLMTAIPAREAGVKEIILVTPPGANGKIpaptLAAAQIAGVDRIFACGGAQAVAALAFGTKSIPKVDKICGPGNIFVTLAKKAVFGVVD---IDGLQGPSEVLIVADQYANAEYCASDILAQAEHDALASSILITTSEDLANRVNDIVESKADTCSRRDIIKQSLrDNGLIAVVDNINEAIKLANMYAAEHLCLLVKDSEKYLTQINHAGCIFYGEKASVVMGDYVAGPSHALPTSGTARFSSPLNILDFVKYIDIVKVDKQDIAKLGQAAATIAKAEGLECHAEAVLKRLE------
>UniRef50_Q4P7D9(441-896:896) Putative uncharacterized protein n=3 Tax=Eukaryota RepID=Q4P7D9_USTMA  E=1e-149 s/c=1.16 id=48% cov=98%
------YRYEDLSAAQRKELLKRPALR-TEQVMDICRPILRSVKERGDAALLELTEKFDKAKLTnAVRLPPFVDDSVMAQIKPEVKVAIDIAYNNIYKFHKAQKTTfgnksagatgsgsadgsegaqdgVLEVETMPGVVCRRFARPIESVGLYVPGGSAVLPSTALMLGVPAQVARCPTVVIATPPradgSISPEVLYCASKVNASAILCAGGAQAVAALAYGTESCPKVDKIVGPGNQFVTAAKMLVQNETDAiVSIDMPAGPSEVLVIADREADAAFVASDLLSQAEHGPDSQVVLVgiaLSSSELA-AIEAEVDRQARALPRVDVVRQAIDKSVTVIVPDRATAMEWSNAYAPEHLILQTRDAESLVECVQNAGSIFVGPWSPESCGDYMSGTNHSLPTAAYAKSYSGVNVATFEKCITSQSLTQQGLKGFAQNVIDLAMCEGLQAHAMAVKIRLDRIQS--
>UniRef50_Q483H8(7-442:446) Histidinol dehydrogenase 2 n=15 Tax=Proteobacteria RepID=HISX2_COLP3  E=1e-138 s/c=1.14 id=35% cov=97%
---------SDLSAEQRNKLLQRT-ESNLDNFIDIVKPIIENVKLNGDKALSEYAKKFDKaeVSTDQIQVTQAEFDEAFTLVDEEVIQTLSYSIDNIKKFHEAQMPEEmWMKQIRPGCYAGDRFTPINAVACYIPRGKGSFPSVAIMTAVPAIVAGVPTAIIITPPgtdgKVDAATLVVAKLVGIDKVFKCGGAQGIAAVAYGTNTVPKCDKVVGPGSPFVVAAKKLLADIIHPGT---PAGPSEAIVLADDTANPKLAALDLLVEAEHGPDSSAFLVTNSKELAEQAQVAINEYWQHMDrlRVDFSSTVLsgDNGGIVLTSTFEEAVDFCNDYAAEHLLILSKSPFDHLGKIINAGEILLGENTPISIANYTLGPNAVLPTSMAAKTASPLSVFDYLKSCSIGYLTREGYEELAPHTYRFAKYEGFDAHANAVShLRDEAIKSE-
>UniRef50_Q8TXG3(25-431:431) Histidinol dehydrogenase n=1 Tax=Methanopyrus kandleri RepID=HISX_METKA  E=1e-138 s/c=1.22 id=42% cov=92%
------------------------------EVLPDVERIFEDVVERGDEALLEYTERFDGVKLeaEDLRVSEDDFEVARELVDERTVEALEEAAHRIEEFHRKTLPRvDRITFDVEGTECGLTLRPIPRVGCYVPGGRAAYPSTALMTVIPARVAGCREVVVCTPPADNdvrasPEVLVAVEIAGADAVYRVGGAQAIAALAAGTETVLRVDKIVGPGNVYVTAAKLLAYSR-GLTDVDMPAGPSEVFVIADDSANPDWLARDLIAQAEHDPHAAAVLATDSEEIARAVKERVEELLdAGIEREEIVLKALDRNGWIVVlDSLEECVRLANRYAPEHLQLCVENPEELLQDVENAGAVFVGHLTAVPFGDYATGPNHVLPTGGFARARGALGTWDFVKIIPIQRLREGDVERLAPIVEELAEREGLPNHAEAVRARRS------
>UniRef50_A6UA68(20-431:432) Histidinol dehydrogenase n=4 Tax=Proteobacteria RepID=A6UA68_SINMW   E=1e-137 s/c=1.19 id=38% cov=94%
----------------------RDAVSDTAPVEKTVKEIIANVRERGDAAVREYSAAFDKVELEKFEVSQEERLKAVAELDPQTREDTEFAIANVRAFAEAQLKTilPLEIETLPGLHLGHRVIPIEIVGCYVPGGRYPLLSAPVMTIVPAKVAGCDQVIACLPPNAHPAMIAGCHLSGADRIFRVGGAQAIAAMASGTETIPAVDKIVGPGNAFVNEAKRQVFGQV---GIDQLAGPSEIFIVADETGKAAMIATDLLAQAEHDVRTRVGLITTDRKLAEETLVEVEKQLQDLSTANVASVAWkDYGEITVCEDETTMIAYSDYIAAEHLQVHTRDPQATARKLRNYGSLFIGELASVVYSDKCCGTNHTLPTMAAGRYTGGLWVGSYLKTCTHQWLDERGVAAVAPAAVRQSATERLEGHRRAAALRLSPQQFAA
>UniRef50_P73058(1-434:434) Histidinol dehydrogenase 1 n=11 Tax=Cyanobacteria RepID=HISX1_SYNY3   E=1e-137 s/c=1.13 id=38% cov=97%
-----ILKLSHLTPQQLNQ-LKRRSEQNIDQALAIAKEVIEQVKMEGDAGVLHYSRQFDfaGATAENLRVSEAEFAEAEKLVDPELRRAVEHAFRNIEKVHAGQMPPPMHLaEIEPGVFAGEKITPLPTVGLYVPRGKGAFPSMMLMLAVPARVAGVKKIVVCTPPdkegKVEPVSLVTARMAGVDEVYKLGGVQALAAIAYGTKTVSKVDKLIGPCSIYGAAAKRLLSGIVD---VGLPAGPSESIVLADETTDPKLAALDLLIEAEHGSDSAALLVTHSASLAEKALGYLGEYLEKLPpwRKKFCEDGLgSYGGILLTDSLQASLDFINDYAPEHLQVLTADPLKLVGKIDNAGEILLGNYTPSSAATYAIGVNAVLPTGGFARSYSAVSVFDFLKRSTLAYLTEEGFAGVKETVTTLADYEDFPAHALAIRERENLL----
>UniRef50_Q13I58(10-426:443) Histidinol dehydrogenase n=22 Tax=cellular organisms RepID=Q13I58_BURXL  E=1e-136 s/c=1.17 id=35% cov=92%
---------------------------SDAKVRAIVESIIQHIEEKGDEAVREYSRKFDNWDPGDFRLSRPEIETARKQLSAREIEDIAFAQTQVRNFARIQRdsMRDVETETLPGVVLGHKHIPMNAVGCYIPGGKYPLLASAHMSVLTAKVAGVARVVSTAPPyqgKPHPAIVTAMDMAGADEILVLGGIQAVVAMAVGTPTVAPVDMLVGPGNMFVAEAKRQLYGRV---GIDLFAGPTETLVIADESVDGELCAVDLLGQAEHGATSPSILLTNSEKLARDTLAEIERQLKILPTASIAAQSWaDCGEVIVCDTYEEMLQVADDIASEHVQVMTEDPDFFLNNMTNYGALFLGPRTNVSFGDKVIGTNHTLPTNRSARYTGGLWVGKFLKTCTYQRVtTNEASAIIGEYCSRLCHMENFAGHGEQANIRV-------
>UniRef50_Q1AX10(5-415:418) Histidinol dehydrogenase n=1 Tax=Rubrobacter xylanophilus DSM 9941 RepID=Q1AX10_RUBXD  E=1e-133 s/c=1.16 id=39% cov=94%
------LDARGLDAREVVRRLRRPRGFLSREVRAAVRQVVEEVRERGDEALLEYGERFDGVRPDPLRVPREEIERARAALPGELAEAFRTAIENVRRFHERELDRSWELE-RGGARLGQRVRPLRRAGIYVPGGHGAYPSTLVMTAVPAQVAGVEELCVCTPPGpdgrANPRLLAVAGLLGIGEVYAAGGAQAVAAMAFGTESVPRVDKIVGPGNDYVTAAKLEVFGEV---GVDAPQGPSELVVVADGSARPERVALDLMAQAEHLSGATSVLLTPSGALASGV----EPLLSGRPSEHIT--------LVLVRDLEQALEISNLYAPEHVHLNCEGAGAALERVEAAGLVAVGDLSPVALSDYAAGPSHALPTGGTARWASALGTHDFLTRINHMRFSREALRELGPHVERLARMEGFENHAASVAARREK-----
>UniRef50_Q3IQR5(7-422:422) Histidinol dehydrogenase n=10 Tax=Halobacteriaceae RepID=HISX_NATPD   E=1e-133 s/c=1.14 id=41% cov=95%
----------DLSPEARAALFERDAGI--EDARESVRDIIGRVREEGDVALRSYAKEFDDVDIGTLAVT-DEAERAYDDLDDDLRDAIETAAENIRTFHERQVPDDWR-EQFDGRELGRRYRPLERVGVYAPGGTAAYPSSVLMGVIPAVVAGVDHVAVATPPaeELPAATLAAAHVAGADAVYQVGGAQAIAALAYGTESVSAVQKVVGPGNRWVTAAKAEVRGDVE---IDFLAGPSELLVVCDDTADPELIAADMVAQAEHDPNASVVCVSDDEATAEAVADACERQATARERTEAIESALENdaSAVLCARSMSEAVLFAEEYAAEHLSIVAADEEALLDRIDSAGSVFLGGFSPVAVGDYASGTNHVLPTGGLAKVAGGLSVDHFVRSTTVQKLDEDALSSLRETVTTLARAEGLEAHAESVDKRFD------
>UniRef50_Q5YYQ0(12-444:445) Histidinol dehydrogenase n=8 Tax=Actinomycetales RepID=HISX_NOCFA   E=1e-132 s/c=1.09 id=38% cov=96%
------------STAELRAALPRGGVDV-DSVLHHVRPVVEAVRERGAAAALEFGEKFDGVVPATVRVPAAELARALDELDPAVRAALEESIARARRVHADQRRTDTTTEVVPGGTVTERWVPVARVGLYVPGGNAVYPSSVVMNVVPAQTAGVGSLVVASPPQAnfgglpHPTILAAAALLGVEEVWAVGGAQAVALLSYGgtdTDGAPldPVDLITGPGNIYVTAAKRLCRGLV---GIDAEAGPTEIAILADATADPAHVAADLISQAEHDVLAASVLVTDSVALADAVDAALTAQLAVVKHAERVRTALtgKQSGTVLVDDITQGLRVVDAYAAEHLEIQTADASAVAARVRSAGAVFVGPYAPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVEYTEAALKDVAGHVVALADAEDLPAHGQAVTVRFEAL----
>UniRef50_Q82AA6(15-433:441) Histidinol dehydrogenase n=29 Tax=Actinobacteridae RepID=HISX_STRAW   E=1e-131 s/c=1.12 id=36% cov=94%
-------------GSALRDLLPRADFDVSAALEK-VRPICEAVHHRGDAALIDFAEKFDGVRLESVRVPARALADALEQLDPAVRAALEESIRRARLVHREQRRTTHTTQVVPGGSVTEKWVPVDRVGLYAPGGRSVYPSSVVMNVVPAQEAGVESIALASPAQAefgglpHPTILAACALLGVDEVYAAGGATAVAMFAYGTESCAPADMVTGPGNIWVAAAKRYFTGKI---GIDAEAGPTEIAVLADSTADPVHVASDLISQAEHDPLAAAVLVTDSVELADAVEKELEPQVAATKHiDDRIVPALKgrQSAIVLVDGVDEGLRVVDAYGAEHLEIQTADAAAVADRVRNAGAIFIGPWAPVSLGDYAAGSNHVLPTGGCACHSSGLSVQSFLRGIHIVDYTKDALADVAHHVVTLAEAEDLPAHGAAIKAR--------
>UniRef50_C0G418(1-356:444) Histidinol dehydrogenase n=2 Tax=Rhizobiales RepID=C0G418_9RHIZ   E=1e-130 s/c=1.31 id=40% cov=80%
----TTLRQTDPDFEQKFAAFLSGKREVSEDVDRAVREIVDRVRREGDSALLDYSRRFDRIDLEKtgIAVTEAEIDAAFDAAPASTVEALKLARDRIEKHHARQLPKDDRYTDALGVELGSRWTAIEAVGLYVPGGTASYPSSVLMNAMPAKVAGVDRIVMVVPAPdgnLNPLVLVAARLAGVSEIYRVGGAQAIAALAYGTETIRPVAKIVGPGNAYVAAAKRIVFGTV---GIDMIAGPSEVLIVADKDNNPDWIAADLLAQAEHDTAAQSILMTNDEAFAHAVEEAVERQLHTLARTETASASWrDFGAVILVKDFEDAIPLANRIAAEHLEIAVADAEAFVPRIRNAGSIFIGGYTP-------------------------------------------------------------------------------
>UniRef50_C0GVA3(15-419:436) Histidinol dehydrogenase n=1 Tax=Desulfonatronospira thiodismutans ASO3-1 RepID=C0GVA3_9DELT  E=1e-129 s/c=1.15 id=33% cov=92%
----------------------------NSRIREAVTFLLDDIRTRGEPAVREMAAKYDGWS-TDFVLQEEKKERLIAMVPEQVKTDIRFAHDQVFNFARMQRQsiQDFEVRPHPGVRLGQRVLPVDVAGCYVPGGRFAHACSAIMSVATAKAAGVPFVVACSPPreeSIAPAVAFAMDLAGADVILELGGVQGVAAMAYGYFTNRPADILVGPGNAYVAEAKALLAGD-GTCGIDVYAGPTESAIIADRSADPMTIAIDLVSQAEHGPDSPVWLFTDCRDLAYQVLNLVPRVIADMPDPHVPKTAWaDFGEIILCNNRDEICRVCDTYAPEHVQILAADPDWWLESLRSYGSLFLGEGSSVAHGDKCSGTNHILPTRKAAQHSGGLSVHKFLKISTYQEIDTEASKRFSAVASRLSRVEGMEGHARSCDWRL-------
>UniRef50_Q46N53(9-421:436) Histidinol dehydrogenase 2 n=50 Tax=root RepID=HISX2_RALEJ   E=1e-127 s/c=1.11 id=34% cov=92%
-------------------------QTETATAQKVVTEMLAEIQARGKDAVRQYAKQLDGWS-GDIVLTPDQIREQTKDVPAGVRADIDFAIRQVTDFALAQResLKEFSVELHPGVTAGQRVLPVNVVGCYAPAGRYAHIASAYMGVATAKAAGVKTVVACSSPfrgqGIHPHVLYAFQAAGADVIMALGGVQAIASMAYGLFTGKPADVVVGPGNKFVAEAKRSLYGQV---GIDVFAGPSEVAVIADETADPAIVASDLVGQAEHGHESPAWLFTTSRDLADRVMALVPELIAKLPPtaRDAATAAWrDYGEVILCGTREEVVEISDRYASEHLEVHTADLDWWLANLTCYGSLFLGEETTVAFGDKTSGPNHVLPTKGAARYSGGLSVHKFMKTLTWQQMTREATRQIGQVTARISRLEGMEAHARTADDRMAK-----
>UniRef50_C7RAI8(14-404:405) Histidinol dehydrogenase n=1 Tax=Kangiella koreensis DSM 16069 RepID=C7RAI8_KANKD  E=1e-124 s/c=1.14 id=35% cov=89%
---------------------KRPNLTQSPELFQQVAKLLKEIETGGDLAIDNLSKRFDGFQPRKIELRPYRDYE----LEPQLLNSIEQAAQRIEAFCQLQKgsLQPQQIEEASGVFGFQ-YSPIEAIGAYIPGGRFPLISTALMTLIPARVAGCQRRVACSP-SVHPAILAAASLAGATEFWQIGGAQAVAAMAYGYQTMLPVQMVVGPGNQYVNVAKQLLQSRIK---IDVAAGPSELLILADSNANQEWLIADMAAQAEHDPQAQSVLVSDDIAFLQSIGQQLtaNDELNNLLKGEQI-------VLLQANDCEAMIRFSNRYAPEHLLL--ADERIASQSLKHYGSLFIGQNSAVAFGDYCAGPNHTLPTMGSANRSSGLCVQSFMNIQSYQQINDQGRIQLAEIGRPLAEAEQLVWHERSMQVR--------
>UniRef50_A8M914(11-398:399) Histidinol dehydrogenase n=1 Tax=Caldivirga maquilingensis IC-167 RepID=A8M914_CALMQ  E=1e-107 s/c=1.01 id=35% cov=86%
---------------------------------DRVRGIINDVKEHGDEALLRLTSELDGVKLSSIELSQSELRALASGIEPRVREALDEVMASVESFNTGVKPRDFEDY-HRGLRRGVKWVPLSRVGLYVPKG---YFSTLVMTGVLAKVAGVEEIIAVTPPRrdglIDPEIAYVALRLNA-RVFRVGGAQAVAALAFGTESVPRVDKIIGPGNAYVQAAKLLVSSHV---GIDGVEGPTELVTCADPGIKPITVALDLAAQLEH-AGAVGVVVTWSEGYLTAIEDE----LSKLTNAPYFST--------LVNEPSECVNVINEVAPEHASIW--GVKIPIEGIRNAGAVSI--MAPSALVDYAAGPSHVLPTGGSARWRGVLTPMDFMKPIAYVEpTSGDEARRLGELGAVLGLREGFRRHSEALTNWINE-----
>UniRef50_D1KBK9(5-122:146) Histidinol dehydrogenase n=1 Tax=uncultured SUP05 cluster bacterium RepID=D1KBK9_9GAMM  E=6e-16 s/c=0.74 id=27% cov=21%
---------QQADFQEKLSKLLAWESVSSTDIAQTVDDIIANIRQNGDQALIDYTNKFDGMdvsDISALTVDQSALKKAFDSLAEKEKTALQSAADRVRDY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_O26327(2-424:426) Histidinol dehydrogenase n=6 Tax=Euryarchaeota RepID=HISX_METTH   E=1e-165 s/c=1.38 id=45% cov=94%
------------------ELVERARLDV-DDVLGPVADIISMVRDGGDDALRELTGRFDGVTVENFRVSREEIEEAHKNLEPGVKEALREAASNIEEFHRMQMPSGWMSEVRPGVMAGQLVRPIDSVGCYIPGGRAVYPSTILMTVIPARIAGVERIVCCTPPaqdgSVPDAVLVAADMAGASEIYRVGGAQAVAAMAYGTETIRPVDKIVGPGNIFVTAAKKLVYGEVD---IDFPAGPSEVLIIADETASPEYIALEILAQAEHDPQAASVLVTDSRDLALEVKEMVHENIKYMERANIIRESLErYGMIVLTADIDEAVDFSNAYAPEHLVIMTDSPEETLEGIRNAGSIFLGELSPVAAGDYGSGTNHVLPTSGCARMYSGLSTESFIKKPTVQRITKEGLRNLQGTVLKLAEYEGLHAHAESFRRRL-------
>UniRef50_Q722Y3(10-425:427) Histidinol dehydrogenase n=20 Tax=Firmicutes RepID=HISX_LISMF   E=1e-164 s/c=1.39 id=42% cov=92%
--------------------------NTSIQVETEVKTIIEKVKTAGDQALFDFTSKFDGVGLTELRVPAADIQAASAKIEPAFLDALQQAKVNIESFHSKQKQHAFLDSEKDGVIRGQLIRPLETVGVYVPGGTAAYPSSVLMNVLPAKIAGVKRIVMITPPgenGINPYVLASAQLAGVDEIYQVGGAHGIAALAHGTESIPKVDKIVGPGNIYVATAKREVFGLVD---IDMIAGPSEIVVLADENANPAFIAADLLSQAEHDILARAILITTSKKIAEETQNEIDKQLENLPRKAIAQKSIEtRGKIIIAATTQEMFDIMNEIAPEHLEVQLENPMNYLYQIKNAGSIFLGSYASEPLGDYFAGPNHVLPTSGTAKFFSPLGVEDFTKRSAFISYTKEALAKEKDAIVLLAKKEGLDAHAKAIQIRFEE-----
>UniRef50_B0TY46(1-432:432) Histidinol dehydrogenase n=2 Tax=Francisella philomiragia RepID=B0TY46_FRAP2  E=1e-160 s/c=1.31 id=45% cov=98%
-----IYNWQELSLVKQAELLSRPVSANKASLVAGVRNILNAVKQNGDKALLEFTSRFDGVDLDNIEVSAHEIKEAYSLVSQDDIELVKNSIARISNYHEVMKPKTTVCDTNDGVVCKKIYKPIEKVGLYVPGGSAPLVSTLIMLAAPAQIAGCKEIYVTTPcdkeGNIHPLILIAADICKVSKIYKLGGAQAIAALAYGTETVTKVNKIYGPGNSWVTEAKQQVSNDSQGAAIDLPAGPSEVLVVADEVADARFVAADLLAQAEHGTDSQALLITTSQILADKVRDEVSKQTSTAQRKAIIEKALENSAIIVVDTLSQAINIANEYASEHLILNIETADNYIDSIENAGAVFVGPWAAEALGDYITGSNHVLPTYGYAKAYSGLATIDFMKAISIQNVSKQGIKNIGQIAMRLADIEGLKAHENAIAIRLESL----
>UniRef50_Q2NHT1(2-407:407) HisD n=1 Tax=Methanosphaera stadtmanae DSM 3091 RepID=Q2NHT1_METST   E=1e-158 s/c=1.38 id=41% cov=93%
---------------------------NSSDVIQPVQEIIANVCENKDKALHDYTLKFDKADISDFKVPVETIKQSVENISPKLRKALEDAAENISKFHKAQIPSDWTMTVKDGVKAGQIIRPLSRVGCYIPGGRAAYPSSILMTVIPAKIAGVEEIICCTPPDkdgcVSDEILAAAYIAGVTDIYMVGGAQAIAAMAYSTQTIPSVDKIVGPGNIFVATAKKLVYGDVD---IEFPAGPSEMLALVDETANPEYIATELLAQAEHDPNAATILVSTSKEVAQKTVEHVMEYLKTQKRSDIIEESLsKYGHVLVASSMEDAIDFTNAYAPEHLVIVTKDHYKTLESINNAGSIFLGNLTPVAGGDYGSGTNHVLPTSGGARMYSGLSAESFLKKPTIQELSPEGVKNIKDMVINLAEAEGLYAHALSIKKRAEDME---
>UniRef50_B3TCH3(25-440:444) Putative Histidinol dehydrogenase n=1 Tax=uncultured marine microorganism HF4000_APKG10K24 RepID=B3TCH3_9ZZZZ  E=1e-155 s/c=1.32 id=39% cov=94%
-----------------KAVLDRTHQAFGEDVspEQSVLKMLQDVRQDGDAAVRRYSKLLDGVELSSFKVEKEQLAQAAASVSTELRESLELAAERIRQFHQAVMPKDWLDEEGG---LGQLVRPLERVGLYAPGGTAAYPSTVLMTAIPARVAGVNEVILCTPARpgeaLNPAVLVAAEISGVDTVYQIGGVPAIGAMAYGTDSVPKVDKICGPGNVFVAYAKKLVQGQVD---IDGVFGPTETVVIADESADPGFCAADLIGQAEHDPLATAILITDSQDLIDRVERELDEQLNIQLRGDLARQALErQGRIVLVESVAEAVELADRIAPEHMCLMVQDPWKWAGTVKHAGGLFLGEYSPEVMGDYVAGPSHVMPTGGTARFSSALSVHQFLRTMPVVSLSADDFQKLGPAAIEIAKAEGLDGHATAVRMRLDKLQK--
>UniRef50_D2RJQ0(33-448:448) Histidinol dehydrogenase n=7 Tax=Firmicutes RepID=D2RJQ0_ACIFE   E=1e-155 s/c=1.32 id=43% cov=92%
----------------------RPLTAAEE-----VDIIVNDIRNKGDEALFEYTKKLDGADLRPatIRVTEEEFAEAEKAVDEKTMGAIRRAIANVRKFHEEQLPKTWLTPRAYGSFLGQKMTPVDSVGIYVPGGTAAYPSSVIMNAVPAKVAGVPRIAMAAPagrdGKMNPYVLATAKEIGITEIYKMGGAQAIAALAFGTETIPKVEKITGPGNIFVTLAKKAVYGHVD---IDMLAGPSEILIVADKTADYQYLAADLLSQAEHDPLACAILITDDEDLAGKVAEEVEVQLQKLPRKEIAAQSLAvQGKIILAKDMDTVVEMANISAPEHMEINTREPFALVPRIRNAGAIFLGAYSPEPLGDYYAGPNHILPTGGTARFYSVLNVETFMKKTSIISYTKEALAEAADDIIAMAEAEGLQAHANAIRIRKGAL----
>UniRef50_B9KYT3(48-446:448) Histidinol dehydrogenase n=1 Tax=Thermomicrobium roseum DSM 5159 RepID=B9KYT3_THERP  E=1e-150 s/c=1.34 id=41% cov=91%
---------------------------------QVVERIIDDVRSQGDDAVRRYTLAFDGAHLDTFLATPEEFLRARRAITPELEAALRFARDRIVAFHRRAIPRSWIEFDETGAF-GQLVRPVDRVGIYVPGGRAPLPSSLLMTAIPAQLAGVRDIVVCTPPGrdgtISPAVLAAAELLGIERVFKIGGAQAIAALAYGTQTVPAVDIVAGPGNLFVVLAKRLVYGDV---GIDQLPGPTETLLIADEQADPVLCAADLLAQAEHDPLACAILITPARTLAHKVAQELERQLQQLDRSEIARAALEaNGAIIIVPDLERAFDLANLFAPEHLCLLVRDPWRYLDRVRHAGGVFLGETSPEVIGDYTAGPSHVMPTGRTARFASPVTVQTFLKVTSLVAVAPKALEQLGSPALQLAMSEGLTAHAAAIEHRLER-----
>UniRef50_D2RSH8(8-425:432) Histidinol dehydrogenase n=1 Tax=Haloterrigena turkmenica DSM 5511 RepID=D2RSH8_9EURY  E=1e-134 s/c=1.15 id=39% cov=95%
----------DLGPADRTAFFDRDAGI--DAISDDVREIVDRVHEEGDVAVREFTSEFDDVELGNIDIT-DACERAYEDLEGDVREAIETAADNVREFHEAQLPEDWRREFGPGRELGRRFRPIERVGVYVPGGSAAYPSSAIMGVVPAVVAGVDHVAVVTPPadELNPVTLAAIHVAGADAVYSVGGAQAIAGLAYGTETITRVQKIVGPGNKWVTAAKAAVRGDVE---IDFLAGPSEVVVVADETADPDLVAAELVAQAEHDPNASVVAVTDDAETADAVAAAVDGQTEARKREDVIRGAFENdaSGVLLARSMSEAILFTEEYAPEHLSIIADDEESILERIDSAGSVFLGPNTPVAAGDYASGTNHVLPTNGGARVTGGLSIETFLRSTTVQRLSAEGLADIGDTITTLADAEGLEAHAESVRQRLE------
>UniRef50_Q2HFX2(431-817:817) Putative uncharacterized protein n=1 Tax=Chaetomium globosum RepID=Q2HFX2_CHAGB  E=1e-134 s/c=1.24 id=48% cov=87%
-----VFDMATASRKELDEALRRPSQKSSDTIMKIITPIIDD----------------------TSPVLKAPFPESLMQLPTETIKAMDVSFENIRKFHAAQKeEKPLQVETIPGVVCSRFSRPPEAVGLYVPGGTAVLPSTAFMLGVPAMVAACKKIVLASPPRSD----------------------AVAAMAYGTESVSKVDKILGPGNQFVTAAKMFVSNDTNaGVGIDMPAGPSEVLVIADKDANPAFVASDLLSQAEHGVDSQVILIAIDLTDAQllAIEDEVHKQAMALPRVDIVRGSIAHSLTVRVKTVDEAMEISNQYAPEHLILQIKDAESVVDKVMNAGSVFIGEWTPESVGDYSAGVNHSLPTYGYAKQYSGVNLASFVKHITSSNLTAEGLRNVGEAVMQLAKVEELEAHRRAVSIRL-------
>UniRef50_C7LZ86(1-430:432) Histidinol dehydrogenase n=1 Tax=Acidimicrobium ferrooxidans DSM 10331 RepID=C7LZ86_ACIFD  E=1e-124 s/c=1.04 id=37% cov=98%
MASLTLVDLRETTGALRRDDLPGVALPV-EGPRALVREIVQSVRTGGDGALADLTERFDGVRPRALVLGREAMAAAYERLDRRLAEALRVARDRVREAYEAERPAASSL-VADGIEVRRRIVPVERAGCYVPGGQARYPSSVVHTATVARVAGVRDVVVATPPlpdgGLDDATLAACHLAGVDTVLLAGGAQAVAALAYGTESLERVDVIVGPGNLFVSLAKQEVAADVGVPG--AFAGPSEVVVVADGSLEPRVAAIDVAVQAEHGPHGLAWLVTWDARWAEQVLEELAAYVEASPRRAQLESTLEaHGYLALVRDRDQARLVADAIAPEHLELLYDQAVRDADRVRHAGVVFVGRAASAAFGDYVAGPSHVLPTAGTARFASVLGLEDFQRRLHVVEVHDEALSRLGWAVEALADAEGLVAHADSIRIRREA-----
>UniRef50_B5YLM0(48-439:441) Histidinol dehydrogenase n=1 Tax=Thalassiosira pseudonana CCMP1335 RepID=B5YLM0_THAPS  E=1e-113 s/c=1.05 id=37% cov=86%
------------------------------------------------KALISIARRLSDILPasSSYTVSSAQCKEAFDSLSDEDRRSLLNIHARVKLFADAQRGSVVDVEvDIPGGKAGHTVSPCRAAGCYAPGGRYPLPSSVLMTVVTARSAGCPYVVLASPRP-APITLAAAHVAGADVVLCVGGAQAIGCMAYGvdeydgedggtkVDAIPACDVIVGPGNKWVTAAKSIVNGH---CGIDMLAGPSEVLVICDHTANAEIVAADLIAQAEHDVVARAILVSDDKTVIDKVDQEVEKQVECLpePNRSTAKEALKQSFSILCKDIDECIAMSDKLAPEHLEIQTLNSQSVGMKCSNYGGLFIGTHAAEVLGDYGAGPNHTLPTGGTGRYTGGLSVFNFLRIRTWMRIDEEGkSQEMVEDSVRMARLEGLEGHARAAEKR--------
>UniRef50_B7FPZ7(1-334:347) Histidinol dehydrogenase (Fragment) n=3 Tax=Eukaryota RepID=B7FPZ7_PHATR  E=1e-104 s/c=1.14 id=41% cov=76%
----------------------------------------------------------------------------------------------VLAFATMQRSSVVDKEmDIPGGKAGQTVRPCGAAGCYAPGGRYPLPSSVIMTAVTARAAGCETVVLSSPKP-APITLAAAYLSGADHFLCVGGAQAIASMAYGIvdSDVPRCDVICGPGNKWVTAAKSIVNGH---CGIDMLAGPSEVLVICDDTANPEIVAADLIAQAEHDVVARAILLSTSDAIIEQVDENVSKQIEALpePNRSTALEALKQSFAVKCESLEQCIAISDDIAPEHLEIQTRDAMKVGEACNNYGGLFIGEHAAEVLGDYGAGPNHTLPTGGTGRYTGGLSVFNFLRVRTWMRVDnAAASQTMVNDSIIMARLEGLEGHARAAETR--------
>UniRef50_P72946(50-375:409) Putative histidinol dehydrogenase 2 n=1 Tax=Synechocystis sp. PCC 6803 RepID=HISX2_SYNY3  E=9e-76 s/c=0.88 id=28% cov=68%
------------------------------------------------------------------RVSGAELDAAYQRISQEKLSVIRQACAALEQVYRPQLPKTQVSFPEDGTVRGQRFYPVRRAGFYLEAKRGDALGNLLRQGMLAKTVGVAERVLVT-ETISSTILVAAQEMGIEEIYLAAGVPAIAMLTWGAKNIAPVESITGAGCPRVMAAKQLVSGVV---TIDQTLARTNLMVLADGEANGQWLALDLLAHAEQYPNASAVLLTDRLELGEEVIQSVNRYCREQEHSVHTEKALAHYGLVaIVEDLEACGSWINEFCPHILLLAMEDPWTMVEKVQRAREIYIGHRSPSILGHYLSGAN--------------------------------------------------------------------
>UniRef50_B8NVQ6(11-222:224) Histidinol dehydrogenase, putative n=1 Tax=Aspergillus flavus NRRL3357 RepID=B8NVQ6_ASPFN  E=5e-59 s/c=1.09 id=37% cov=48%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AVAAIAVGTETIRKVDFLAGTGNRFVAEGKRQLFGEV---GIDLFAGPTEVLVLADETADPFTVAMDLISQAGHGPDTPAVLITTCPKVGRETIEIVNKLLSatDLSTPDVAKVSWDaFGEVIIVDTLEELWELGDHYASEQVQVI--------------------------------GTNHILPTRTTARYTGGLWVGKYLKTCTYQEVTlPESSGKLGRLCGRAARPERFEAPARSGDLRANR-----
>UniRef50_C5GHZ5(2-215:281) Histidinol dehydrogenase n=2 Tax=Ajellomyces dermatitidis RepID=C5GHZ5_AJEDR  E=1e-54 s/c=1.01 id=34% cov=48%
----------------------------------------------------------------SFKLSEGDIEAAVVKVSEQTIKDIKEAQAN-----------------------GYIW--VRRIFLLVQLGRRFLPSSFHTQEVQfcnSKVAGVNHVTMCTPPingKIPNATTATTHLVGANEIFILGGAQAIAGMAVGTESIRKVDSI-------------------AEIGVDLFAGPTEVP------------ATHLLSQAEHGPDSPAVLITTSEDSAKQVMTLIDRFLETLSTAAIASTAWrSFREVVIVDSIDEAYALGDEYAFDH-----------------------------------------------------------------------------------------------------------
>UniRef50_UPI00019859BD(90-516:524) PREDICTED: hypothetical protein n=1 Tax=Vitis vinifera RepID=UPI00019859BD  E=1e-165 s/c=1.37 id=49% cov=97%
---------SELSQAEVNSLKARPRIDFS-SIFNVVHPIVDDVRSRGDAAVKDYTTRFDKVELDRLIENVAELPD--PELDAGIKEAFDVAYDNIFAFHAAQKSAEKIVENMKGVKCKRVARSIASVGLYVPGGTAVLPSTALMLSVPAQIAGCKTVVLATPPsqdgGICKEVLYCAKKAGVTHILKAGGAQAIAAMAWGTTSCPKVEKIFGPGNQYVTAAKMILQNSEAMVSIDMPAGPSEVLVIADKHANPVHIAADLLSQAEHGPDSQVVLVIAGDGVdLRAIEEEISKQCQSLPRGEFASKALSHSFTVFARNMVEAISFSNLYAPEHLIINVKDAEKWENFIENAGSVFLGQWTPESVGDYASGTNHVLPTYGYARMYGGLSLDSFLKYMTVQSLTEEGLRKLGPYVEAMAEVEGLEAHKRAVTLRLQDIE---
>UniRef50_C6Y3G2(3-430:430) Histidinol dehydrogenase n=6 Tax=cellular organisms RepID=C6Y3G2_PEDHD  E=1e-161 s/c=1.33 id=47% cov=98%
-----IYSYKDLTKQEVEEICLR-QLEDDVNIQERVKSIVERVKMEGDKALFDYALSFDQIRLEELFIDQQEIMTIAATIPAEAKAAIDTAYQNIKTFHASQLLQEDKVETMPGVTCWRETRAIERVGLYIPGGTAVLPSTFLMLGIPAVLAGCKEIVVCSPPQKDGktncYLAYVATLLGIERIYLVGGAQAVAAMAYGTASVPKVDKVFGPGNRYVTQAKQLIQGNT-MTAIDMPAGPSEVLVLADETAIPSYIASDLLAQAEHGIDSQTILVATSSKIIDETMEQLALQLQVLPRAAFATKAIENSYSVLVNDLEEGMKFSNVYAPEHLILATDNCERLIPLISNAGSVFLGNLTPESAGDYASGTNHTLPTSGYARAYSGVSMDSFMKKITFQHITTQGLRHIGNTVEVLAAAEGLDAHKNAVSIRLKSLD---
>UniRef50_C9LTV1(3-449:449) Histidinol dehydrogenase n=1 Tax=Selenomonas sputigena ATCC 35185 RepID=C9LTV1_9FIRM  E=1e-160 s/c=1.27 id=39% cov=98%
-----IVSAKELGKDKIRKLLVKPpfdEVQLNPKIREANRKifgadltaaevavrIVEDVRRHGDEAVIKYTKLIDGTDfsPEDFQVSEEEFAEAEKNADPAIVASLQRAAHNVRSYHEEQKANSWLTYREKGSILGQSLIPLDRAGIYVPGGTAAYPSSVLMNAVPAAVAGVGEIIMMVPPkngKINPYVLLAAKIAGVSKVYKIGGAQAIAAMAYGTATIPRVDKITGPGNIFVTLAKKAVYGHCD---IDMLAGPSEILIVADETADPAYTAADMLSQAEHDTLASSILITTSAKLAHEVEALLEEQLKGLPRENIARASIENNGlIVIADDIMEALEYANISAPEHMELLTKQPFELLPYVRHAGAVFLGAYSPEPLGDYFAGPNHVLPTGGTARFYSVLNVETFMKRTSIISYTKDALHDVEADIIRLAEAEGLHAHANAVRLRSKERKD--
>UniRef50_P00815(363-791:799) Histidinol dehydrogenase n=17 Tax=cellular organisms RepID=HIS2_YEAST  E=1e-157 s/c=1.30 id=46% cov=96%
------------DKVGVQKALSRPIQKTSE-IMHLVNPIIENVRDKGNSALLEYTEKFDGVKLSNPVLNAPFPEEYFEGLTEEMKEALDLSIENVRKFHAAQLPTETlEVETQPGVLCSRFPRPIEKVGLYIPGGTAILPSTALMLGVPAQVAQCKEIVFASPPrksdgKVSPEVVYVAEKVGASKIVLAGGAQAVAAMAYGTETIPKVDKILGPGNQFVTAAKMYVQNDTQAlCSIDMPAGPSEVLVIADEDADVDFVASDLLSQAEHGIDSQVILVGVnlSEKKIQEIQDAVHNQALQLPRVDIVRKCIAHSTIVLCDGYEEALEMSNQYAPEHLILQIANANDYVKLVDNAGSVFVGAYTPESCGDYSSGTNHTLPTYGYARQYSGANTATFQKFITAQNITPEGLENIGRAVMCVAKKEGLDGHRNAVKIRMSKL----
>UniRef50_Q1Q2D0(25-435:439) Histidinol dehydrogenase n=1 Tax=Candidatus Kuenenia stuttgartiensis RepID=Q1Q2D0_9BACT  E=1e-156 s/c=1.35 id=40% cov=93%
-------------------------LNSSSDIRTTVLKIIQDVKKNGDKAIAAYGKRFDKAPLSPeqFRVKEEEIEDAYKYVTGKFIKAIRLAIKNIQTYQNHIRIQNVKPLRSKGVILDTIYTPIDSAGIYVPGGAASYPSTVLMNAIPAQVAGVEKIVMVSPPKedgnIPPERLVAAKEAGVSEIYKIGGVQAIAALAFGTKTIPSVDKIVGPGNVFVTLAKKEIFGY---AGIDMLAGPSEVLIIADNHANPSYIASDLLSQAEHTPG-ISLLVTSSKLLAKQVLAEITLQIKTLSRSAGTNECLcKYGVIFITKNMNECIALSNAIAPEHLQIMTQNPKAVLSGIKHAGAVFVGDYTPVALGDYIAGPSHVLPTGGTARFSSGLSVNDFIKRTSVITYSQSALRSVQQDVSEISASEGLDAHAKSVKIRLDSGRKK-
>UniRef50_B2A652(3-422:428) Histidinol dehydrogenase n=1 Tax=Natranaerobius thermophilus JW/NM-WN-LF RepID=B2A652_NATTJ  E=1e-154 s/c=1.30 id=41% cov=91%
-----------------------------EDVETrnTVTKIIDQVRTNGDKALFELTQSLDNCSLSKLEVSQEYMKQCYDNLTDKTKEALNFAKDQIEFFASQQLagFKEIECENIPGVKLGYKIKPISSCGCYVPAGRYPLPSSALMSIVPARVAGVERIVAIAPPvrkygGIHPELLAAMYLAGVDEVYIVGGAHGIAALALGTETISKVDFIVGPGNKYVTEAKRQLNGIV---GIDQLAGPSEVLIIADNTASSTNVAADLLAQAEHDPDAVCVLVTTSEQLAKEVNQEIHRQLDELLTWETAAKSWeDYGEIILVDNLDQAIEISDQMAPEHLQLMTDNNSNIMEMVNHYGSLFVGEWASVAFGDYVSGTNHILPTGNSARFSSGLSVGKFLKMSSYQVLTETGAHELSDKCMHLAELEGLEAHKKSAELRAD------
>UniRef50_Q46WL2(14-444:445) Histidinol dehydrogenase 1 n=202 Tax=Bacteria RepID=HISX1_RALEJ   E=1e-152 s/c=1.26 id=43% cov=92%
-----------------------------EAIDRAVAQILADVKDRGDAAVLEYTQRFDRVEaasMGALEISQSELEAALEDLEPKRRAALEAAAARVRAYHEKQKIEcgshSWEYTEADGTMLGQKVTPLDRVGIYVPGGKAAYPSSVLMNAIPARVAGVKEIIMVVPTPggvRNELVLAAAQIAGVDRVFTIGGAQAVGALAYGTATLPQVDKIVGPGNAYVAAAKRRVFGTV---GIDMIAGPSEILVICDGTTDPDWVAMDLFSQAEHDELAQSILLCPDADYIAQVEASIQRQLDSMPRREVIAASISgRGALIKVRDMEEACEIANAIAPEHLEISAENPRQWSEKIRHAGAIFLGRYTSESLGDYCAGPNHVLPTSRTARFSSPLGVYDFQKRSSLIEVSEGGAQMLGQIAAELAYGEGLQAHARSAEYRFKR-----
>UniRef50_Q313T7(1-434:434) Histidinol dehydrogenase n=7 Tax=Deltaproteobacteria RepID=HISX_DESDG  E=1e-151 s/c=1.24 id=41% cov=93%
------------------------RENPENSVEPVVREIMDAIRSDGDAALAGYTRRFDcpDFDPSSLRVAPDAIEKAAREIPRHDLQIITEAADNIRHFHSAQKEEAWFITRPDGTVLGQMTRPVDSAGLYVPGGQGgntPLISSLLMNAVPAQVAGVPRIAVTTPPrkdgTLNPYILAAAHVLGLDEIYCAGSAWAVAALAYGTQTIAPVDFIAGPGNIFVTTAKRMLIGTV---GIDMIAGPSEILIIADSQADAAHVAADMLSQAEHDPLASAILVTPSPQLAAAVHTELEKQVTGLDRADIARASLrDWSAIVVTPDLNSAVELSNKVAPEHLELLVQDTWGLLGSIRNAGAIFMGPHSPEPVGDYFAGPNHVLPTMGTARFSSALSVQSFCKKSSIIAASQTFTQTNAAKIARLARLEGLEAHARSVESRLS------
>UniRef50_A9A0A6(3-433:434) Histidinol dehydrogenase n=2 Tax=Desulfobacteraceae RepID=A9A0A6_DESOH  E=1e-148 s/c=1.23 id=41% cov=90%
-----------------------------------VAAIVADVKKNGDKALERYTRQFDAPKLAAsgFRVTAAEMAGAAKEVDRSFVKAINRAIGQVSEFHAMGLEKTWTAEPRPGVVVGKKVTPVDSAGIYVPgatGGRTPLVSTVLMGAIPAKTAGVRRIVMVTPPrqdgTVNPHLLVAAKKVGVHEIYKVGSAWAIAALAHGTKTIARVDMIAGPGNIYVALAKKIVAGTV---GIDMMAGPSEILVVADGSADPRYIAADLLSQAEHDALSAAVLVTTSMKVARAVSDEVKRQTTGISRWQIARKALaAYGAVFVVKSKKEAFALVNRFAPEHLELHTKNPEKDLDQIRNAGAVFLGPYTPEPIGDYVAGPNHTLPTSGCARFASALSTAHFLKRTSIVSYSKAAFLSEAADVMRIAAVEGLDAHANAVGVRLEE-----
>UniRef50_D0LM64(13-433:438) Histidinol dehydrogenase n=2 Tax=Nannocystineae RepID=D0LM64_HALO1   E=1e-145 s/c=1.23 id=43% cov=96%
------------DSRELRALLER-STSFASEVERAVADILAEVRARGDEAVRAFTEKFDGRSPragSSYEIPPGDWRRAKGELAPEVLAALEQAAERVRAFHARQAEVDRAADfslDGGGMRLDLRIDPLSRVGIYVPGGTARYPSSVLMTAIPARIAGVDEIIMVTP-GASKETLAAAALAGVDRVFEIGGAQAVAALAYGTESVPRVDKIVGPGNQWVAAAKRQVFGVVD---IDSVAGPSEVLILADDSANPRWVAADLLAQAEHDPLAHPVLATTSPALADAVDEELARQLADLPRADIARTALaNQGAAVLVPDQGAAVAFANRYAPEHLELHLREPRAVLGQLRTAGAIFVGALAAEAAGDYMAGPNHVLPTGGAARYASPLGVYDFRKHTSIIEYQAEAVLAQADAIAALAAVEGLDAHGRSMTLRRDALR---
>UniRef50_C9RN89(11-429:429) Histidinol dehydrogenase n=1 Tax=Fibrobacter succinogenes subsp. succinogenes S85 RepID=C9RN89_FIBSS  E=1e-143 s/c=1.22 id=41% cov=92%
-------------------------VAPSKEIHDKVMDILADIKNGGYAKAVEYAQKFDGLKGKNLRVSEAEIKKSAAKCPPEMQRALKQAIKNVRDFHVNQMEDSWLMEGKDGVVLGQRIRPMKRVGLYVPGGAGIYPSTVIMNAVPAIVAGVKDIVVVTPikGEINRAVAFVLCELGITEVYHIGGAQAIGMLAYGAKDgkgkvvVERVDKIVGPGNVFAAVAKKEVFGIVD---IDMVAGPSEVLVLADNTCDPDFVAADLLSQAEHGSGfEAAICITDNMETAQMISECVDIQVENSPKRELLQKVLDNfGRILVVKDWFDGVAIANAIAPEHMEIMTDEAESMAAQIENAGAVFIGPWSSEPVGDYFAGPNHVLPTNGTGRFFSPLGVYDFLKRMSIIKYSEKAIKKNAKAIAVVANEEGFIHHAAAVLKRL-------
>UniRef50_C8WUX6(1-426:426) Histidinol dehydrogenase n=2 Tax=Alicyclobacillus acidocaldarius RepID=C8WUX6_ALIAD  E=1e-143 s/c=1.20 id=42% cov=92%
-----------------------------ADVWEKVERIVEEVRVGGDDALRRLTRALDGVD-APLRVPPEAMEAAFRALRAEVREALARAAERIRRFHEAQLPNDIVIRGEDGETLEMLWRPLHRVGVYAPGGRAAYPSTVLMDVIPAQVAGVRSIALVSPPGpdglPHPAVLAAAHLVGVEEMYAVGGAQAVAALAYGTETIARVDKIVGPGNVYVATAKRMVMGDV---GIDSIAGPTEVVVVADETANPAYVAADLLAQAEHDVEAGAVCLSPSRELLENVHAEIVRQLAALPRRDIAREALErHGALVHVKSLDDAVVLVNDMAPEHVEVVTENPRRVLNGLRTAGAVFLGPYTPEPVGDYFAGTNHVLPTHGSARFSSGLGTLDFMRRMTAATYTAETIARHAPYIEALAEAESLTAHREAVRIRREELR---
>UniRef50_Q4A044(17-416:423) Histidinol dehydrogenase n=62 Tax=Staphylococcus RepID=HISX_STAS1   E=1e-142 s/c=1.26 id=36% cov=91%
----------------------------NEDLYPIVKDICENVRLHGDDALRNYNQQFDQVETCNLEVAYQTLENAYNRLDSDLREALQQSHARIQSYQESIK----WTKQQGTSDCYELYHPLERVGVYVPGGKASYPSTVLMTVTLAKVAGVKNISVVTPPqlnGIPDIVLAACYIAGVDNVYQVGGAQSIAALAYGTETLPKVDKIVGPGNQFVAYAKKYLFGQV---GIDQIAGPSEIALIIDDSADLDAIAYDVFAQAEHDELARTFVISEDEALLKQLEQKIQHILPQIERQSIVQASLnDNHFLIHVNNFSEACDLMNQIAPEHASIQTVSPHDYLNHVRYVGALFLGYYSPEVIGDYVAGPSHVLPTNQTARFTNGLSVNDFLTRHSVIDLSKDTFDTVELTARKLAHVEQLYNHEQSIEIRTSK-----
>UniRef50_B3T638(17-434:434) Histidinol dehydrogenase n=1 Tax=uncultured marine crenarchaeote HF4000_ANIW141N1 RepID=B3T638_9ARCH  E=1e-139 s/c=1.19 id=39% cov=92%
-------------------------QKTSEKDRKTVQAILNDVRKNGDSAVKKYERKFNGRKTSQLRVSNKEIGEAEELPDPTDNIWTKLYLQEWDLYWnlsgRKQKLrkggfcyeKPYFWGGLP-LKTEKRFVPIPSVGCYIPGGQARYPSSVVMSVLPAKIAGVKRIVIVSPPgrdgKIDPLTISAAAMCGVTEIYKVGGAQAIGALAYGTKSIPKVDKIVGPGGKFVSIAKAIVS---EQTSIDMIAGPTELGIMADTSSDPELVALDLISQAEHSKDTMCFVITQSKIIAKQIQKSIEKLIPGTERSSIIRESLtKNGFIAVCKNENEMIELANKIAPEHLELMVKNARSLSKKITGAGLLLIGKNTPSSASDYILGTNHILPTNGFGRTRGGLSVLDFLKLQTIVESKKSTLKALSSDLKALTDAEGLPNHYKAVKRRLD------
>UniRef50_Q67KH6(7-426:439) Histidinol dehydrogenase n=1 Tax=Symbiobacterium thermophilum RepID=HISX_SYMTH  E=1e-138 s/c=1.18 id=40% cov=94%
------------------EFLNRRRTEFYPEIEAQVRAILERVRREGDGALYAFTRQFDGADLEAtgLRVTEAEYREAEAAVSAAFRAALQVAVENIAAFHRPQVPTSWFTTRPDGTIVGQRVTPVDRAGVYVPGGSAPLFSCLLMTAIPAVVAGVPEVIVCTPPdrngRIDPHMLVAARAAGVKDVYKVGGAQAIGAMAYGTATVPRVDKIAGPGNYYVTLAKKLVFG---PVGIDMLAGPTEVMAVDDGSVDAEWLAADLLSQAEH-PNGMVILVTTAgPERIAAVGAAMARHTAALPRAETIRRSVaELGAALAVDTLEEAADLVNAVGPEHLEVGVADPWAFLPLVRHAGSIFLGRWTPEAMGDYIAGPSNVIPTEGTARYASPVCVETFIKRSAVTCYSEAAFRAQAPHAVRLALTEDLLAHAASMQIRLAK-----
>UniRef50_Q4FNE2(13-427:428) Histidinol dehydrogenase 1 n=3 Tax=Candidatus Pelagibacter RepID=HISX1_PELUB  E=1e-137 s/c=1.19 id=36% cov=90%
-----------------------------------VIKIIKDVKKNGDKAILKYEKRFNKNSI--IAPSIKQINRAIQSLDQKVKKAIDLAYDRIYKFHSLQKFKNISYTDKLKNKLEYKYVPIESVAIYVPGSTASYPSSVLMNAVPAIVAGVKRLVMVNPGQKgkqNPAVLYAAKKCKIKEIYSIGGPSAIAAVAYGTKKIKKVDKIIGPGNSYVAAAKKEVFGDVGIEG--MIAGPSEVTIVCDKFSNPEWIASDLIGQAEHDNLAQCILISKDKSIIKKVNYEIINQLKELPRAVIAKNSlLNNGILIYMPSDQKIINTVNKIAPEHLELNTKNYKKVVSKIKNAGSICLGKYAVMAMTDYNVGSNHVLPTNSSARYSSGVSVNEFYKRISYINLSKKGIETLGPSVITLANYEGLVGHAKSVEKRI-------
>UniRef50_D1N997(12-431:431) Histidinol dehydrogenase n=2 Tax=Lentisphaerae RepID=D1N997_9BACT   E=1e-136 s/c=1.16 id=42% cov=89%
----------------------------------------ADVKAEGDAALVRYAAKFDHAELTPaqFRVTGDEIAAAEKQLPARLKSAIRTALRQVRDFAKLTIPKGWTASPRPGVTLGEKFEPLDRVGVYIPGGTAPLVSTVLHTAGIAGAAKVKEIVAVTPPgrdgKVHPAVLYAMKLAGVTEIYRLGGVYGVAALACGTETIAKVEKIVGPGNAYVTAAKKLLYGQV---AIDMVAGPSEILVIADETADPSFIAADLLSQAEHGSgLEQAVLVTTDKAMIDRVEAEFLRQKATLPRLATVDRVQEHGlFLIHTPDLDTAAAIASSYAPEHLEIQTARPEQVARKITAAGAMFLGKWTPEPVGDFCAGPSHVLPTASSARYFNGLETVSFFRRSSIVKYTEAAIRREVSMVEAFAEMEGLAAHGRSGTIRVKPL----
>UniRef50_Q4JW59(13-439:450) Histidinol dehydrogenase n=104 Tax=Actinobacteria (class) RepID=HISX_CORJK  E=1e-135 s/c=1.13 id=39% cov=91%
-----------------------------DSVIPTVAPIVDQVREGGARAALEIGQRFDGVTPDSVRVPAEVIDAAVGTLADDVIAALEEAIKRVRAFHSAIRPEDKQVEVAPGGIVTERFIPVQRVGLYAPGGNAVYPSSVIMNVVPAQEAGVESLVVASPPQEggwpHPTVLAACKLLGVDEVWAVGGAQAVALLAHGStaeggEELEPVDMVTGPGNIFVTAAKRLCRSVV---GIDSEAGPTEIAVLADESANAVEIAYDLISQAEHDTMAASVLITDSEKLADEVVAEMNERYHITENSERVAEALSgqQSGVVLVDDIAAGIRAANAYGAEHLEIHTEDAHGVAAQITNAGAIFIGRFSPVPLGDYAAGSNHVLPTSGTARHSSGLSTLTFLKSVHVIDYNEEGLRGVADTVITLSKSEGLPAHGEAISAR--------
>UniRef50_D2R570(38-454:454) Histidinol dehydrogenase n=1 Tax=Pirellula staleyi DSM 6068 RepID=D2R570_9PLAN  E=1e-134 s/c=1.15 id=41% cov=90%
--------------------------------TEVVETICRDVRERGIAAVLDYSKKLDRADLTPetIRVSQAELDAAHAAADPAFLAAIARIQQNILEFQTAILHKEVEVR-RNGVVLRQRYQPLERIGICVPGGAAAYPSTVLMTAVPAQAAGVSQIVVIAPPTDfganNRDVLATCKAIGVTEVYRMGGAQGVAALAYGVEGIPKVDKIVGPGNLFVALAKRHVYGEVD---IDSIAGPSEVVVISDETTRADFTAADLLAQAEHAPGAS-ILITWSRTALEATKRELERLVQTISRSELTLQSLrDFGCLILVDSPEEACRVTSEIAPEHLHIATENAGALLAKIRNAGATFLGNYSPVALGDYAAGPSHVLPTGGTARWASGLSANHFLRSSSVIDYSAEALRDIAPAIQMLADKEGLTAHRLSVDLRVE------
>UniRef50_O33775(9-398:398) Histidinol dehydrogenase n=12 Tax=Sulfolobaceae RepID=HISX_SULSO   E=1e-130 s/c=1.19 id=36% cov=88%
-----------------------------SRVIPVVKDIIESVKTKGDNALYELTEKLDKVKIDNIKAREEELKTQASKLDPKVKQAIDTAYEQLKAFHEM-LVPPNIGGGYQGISFGVIWRSIEKIGIYVPSGKYSYPSTLLMAGIPAKVAKVKEIYVASPPtqegTVNPALAYVAIKLGVNEVYKIGGAQAIAALAFGTESVKKVYKIVGPGNVYVQAAKYLVSSVV---GIDGIEGPTELVIIADETAKAEYVALDMKAQAEHGPDTYIVLLSNDDELIRRVEEKI-------------KNDKKIYYIIKTKNLDEAIEIANKIAPEHLSLYVKDAYTLMDKIVNAGAISLGN-TPPAIIDYVAGPNHILPTNGWAKIRGGITVYDFIKPTMYANV-RDINKQLLEASISLANYEGFIIHGKSIGARYE------
>UniRef50_Q1D4L9(16-434:437) Histidinol dehydrogenase n=2 Tax=Cystobacterineae RepID=Q1D4L9_MYXXD  E=1e-130 s/c=1.11 id=42% cov=95%
---------SALAREDVRRLLDR-ATGSDARVALRVREIIARVRAEGDQALFELARQFDRVELTALEVPREVCAAALAGLEPSVRDALARAARNIALAHAPQKPQWVEVETEPGVLVGRRPDPLGRVGVYAPGGRAVYPSSVLMGVVPAKVAGVGEVIVCSPPGpdglPHPSVLAAASLAGADRVFSLGGAGAVAAMAHGTESVPRVDRIVGPGNAYVAEAKLQV---VGAVAIEAPAGPSEILVVADDTANPAAVAREMLAQAEHDPEAACVTLALGDALADAIAAEVERQAERAKRWEIVTSALgSRGAVLTVASLEEAWPFVADFAPEHLLIATASPREDLGQVRNAGTVFLGERSSVAYGDYMTGSNHVLPTAGLARAYSGLNLLDFYRWTTYQRVAPTAAASLAEDVGRLADSEGLFAHADAARAW--------
>UniRef50_A9G5W4(1-447:460) HisD protein n=1 Tax=Sorangium cellulosum 'So ce 56' RepID=A9G5W4_SORC5  E=1e-124 s/c=1.00 id=40% cov=91%
-----------------------------ANVTPAVTEIIDNVRRGGTSAVLGYIEKFERRTSKALvRHAGPEAEggfggaEALARLSPEVRAALETAAARIARYHERQRdagdlgpanvtangpaLQAGFSYEEEGVLLGMRVRPLRRVGVYAPGGKARYPSSVLMSAIPARIAGVREIVLASP-SADDATLAAAHLSGVTTLLDSGGAQAIAAMAYGLPELAPVDKIVGPGNAYVACAKKLVFGDV---SIDGITGPSEILALADESADPRLVAADLLSQAEHDEASYALLATTSAKLAEAVARELDAALPELTRRAIVQASLStHAAALVVGSRARLAEIADQLAVEHVAFHVADAEGLFSEIGTLGAALLGDLTPVAAGDYLAGPSHVLPTGGSARFGAPLGVYDFVTRASLIRYSSAALRAQGPIIEKLALAEGLQAHARAVSLRLAS-----
>UniRef50_Q8ZY17(4-368:368) Histidinol dehydrogenase n=5 Tax=Thermoproteaceae RepID=HISX_PYRAE   E=3e-82 s/c=0.84 id=29% cov=83%
------------------------------EVLESVWKIVDDVQSGGLKAALEYSKRLDGVAPEPHLVTPRQgGDPEVVSAALAAAKSLEALYSRIS--------PPAAVDFYGGILRQILWKPVRRAALYVP---ARYISTLVMLAVPARLAGVEEVYVVTPPrGVSEELLAVAKELGVKAVLALGGPHG---LAYAVFHM-GVDVVAGPGGLYVQAAKYILSQYV---GIDGIEGPTELVIYA-EGVPPEVAVRGALAQLEHGPTSFAYLLSPDGELLKKAEE-----LYVRERT----SSMGPLKVKKVGGIDEAVSFIDEIAPEHLEVWGR--REVAYRVRNVGAVSV--NMPSPYLDYVAGISHVLPTGGTARWRGVITPLAFMKPIGIAE--AVGELTLREAARKLAEYEGFKYHGEALR----------
>UniRef50_UPI0001909A69(31-208:287) histidinol dehydrogenase n=1 Tax=Rhizobium etli IE4771 RepID=UPI0001909A69  E=5e-54 s/c=1.20 id=38% cov=38%
--------------------------EVSEDVNAVARAIIDDVKARGDVALCRIfadIRRHRFSPPVPMRVTPEEIDAAVEAVPSEVLGALKLAALRIESHHRRQLPKDDIYEDDLGVRLGSRWTAIEAVGLYVPGGTASYPSSVLMNAVPAKVAGVDRIVIAVPATggaVNPAVLAAARLAGVTEIYRVGGAQAIA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1PYE8(9-429:444) Histidinol dehydrogenase n=2 Tax=Prevotella RepID=D1PYE8_9BACT   E=1e-167 s/c=1.40 id=50% cov=96%
-------------KSEWSRILKRPHLDVS-QLNETVNEILSDVKSRGDEAVRHYEALFDQADLGDLTVSDEEIDEAMSMVSTDLKEALELAYHNISKFHESQLFHGKMVETAQGVVCWQKSVAIEKVGLYIPGGTAPLFSTVLMLATPAKIAGCKDIVLCTPPnhdgKIHPAILVAAHIAGVDRIFKAGGVQAIGAMAYGTQTIPKVYKIFGPGNQYVMAAKQQVS--LHDVAIDMPAGPSEVCVIADEGSNAEFVAADLLSQAEHGSDSQVMLISTSDNLITEVRSQVERQLENLPRREIASDALKNSKFVLVHDMDEAMRLSNEYAPEHLILSTGNFEEMADKVVNAGSVFMGKWSCESAGDYASGTNHTLPTHQYALAYSGVNLDSYCRKITFQQLSENGVSSIGNAVVRMAEDEGLEAHAHAMRIRLKKVDDK-
>UniRef50_Q465R4(1-427:433) Histidinol dehydrogenase n=7 Tax=Euryarchaeota RepID=HISX_METBF   E=1e-164 s/c=1.36 id=44% cov=95%
---------SDVSEAEMQKLLSRGSG--LEDVAKTVSTVLSDVRTKGDSALREYTAKFDKVELANFGVSEEEFQQALSGISPELLDHLKSAAANIRAFHEAQLPKaTWFMELKPGIVLGQKATPLESVGAYAPGGRASYPSTVLMTVIPARVAGVEQVIVCTPPrpdgSVHPLTLAAAKVAGADKVFKLGGVQAIGSMAYGTETVPKVDKIVGPGNVFVTAAKMQIR---DVAEIDFPAGPSEVLIIADESADAVMVASDILAQSEHDPNSVSILVTGSDTLAEAVKREVLVQAEQAARSSIIKSSLENAAILIADSLEQCIGFSNKFAPEHLEIMVADPDFVLDRIKNAGSIFIGNYSPVPVGDYASGTNHVLPTSGYARVYSGLNINHFIKYSSIQRISKSGLESLKETVIALAEEEGLQAHADAIRTR--------
>UniRef50_Q39YP7(4-429:436) Histidinol dehydrogenase n=54 Tax=Bacteria RepID=HISX_GEOMG   E=1e-164 s/c=1.37 id=41% cov=94%
----------------EFAAILARGEETGREVEQVVLDIIADVRARGDEALLEYTRRFDRLEadsVASLQVTEDEVDYAFARVKDEEIAALKLAVERVARFHEKQKQETWLSTGEPDILLGQMVTPLERVGIYVPGGKASYPSSVIMNAVPARVAGVGEVVMVAPTPggeINPHVLVAARFSGVDRIFRLGGAQAVAALAYGTATVPKVDKITGPGNIYVATAKKLVFGQV---GIDMIAGPSEILVINDGSGTPAHIAADLLSQAEHDELASSILITTDRGFGERVAAEVERQLAELSRETIARRSWEtYGAVIVAGSLDEAIAFSNRIAPEHLELAVTNPFDVLPKIRNAGAIFLGHFTPEAAGDYLAGPNHTLPTGGTARFFSPLSVDDFVKKSSIVYFSESGLNRLGGGIVRIAELEGLEAHGRSVSVRLK------
>UniRef50_Q6FEC8(5-430:430) Histidinol dehydrogenase n=50 Tax=Bacteria RepID=HISX_ACIAD   E=1e-158 s/c=1.32 id=41% cov=91%
------------------------------ELLKTVDQIIADVRQYGDEHVLKLTQQFDRhpaHQFSDLELTQEQLKTAFEALTAEIREALELAAERIRSFHQAQKQEGWSYVDALGNTLGQKVTPLDRVGIYVPGGLASYPSSVLMNAIPAHVAGVPEIIMVVPAPngeLNSLVLAAAYLAGVSRIFTIGGAQAVAALAYGTQTIPAVDKITGPGNRFVAAAKRAVFGQV---GIDMIAGPSEILVYAEGQNNAKWLAMDLLSQAEHDTVAQAIFITPDEALLDEVAQAIEEHLAALPKADIARTSIANrGALVLVKDRDEAIELINQVAPEHLELCLDESEAMSQKIRHAGAIFMGRYTPEAIGDYCAGPNHVLPTSGTARFSSPLGVYDFQKRSSLIMCSQEGVKSLAKAADVLAQQENLDAHARSARYR--------
>UniRef50_C4V2I6(48-447:448) Histidinol dehydrogenase n=1 Tax=Selenomonas flueggei ATCC 43531 RepID=C4V2I6_9FIRM  E=1e-155 s/c=1.38 id=41% cov=91%
-----------------------------------VHHIVRDVRSGGDQALLRYTKLLDGLDLSStdIMVSESELQAAADQADAAVLASLERAAKNIFAFHEEQKPKSWMTYRAHGSILGQEVIPLSRVGIYVPGGTAAYPSSVLMNAIPAIVAGVDDIIMSVPTKggvLNPYVLAAAHMLGIKKIFRVGGAQAIAAMAYGTESIPRVDKITGPGNLFVTLAKKEVYGYVD---IDMLAGPSEILILADEEASPKYIAADMLSQAEHDPLASSILITDSADLASNVRCEIQDQLQSLPRMETASASLErNGRIIVTENIQQSVHLANYSGPEHIELLVKDAFHLLPEIRCAGAVFVGSYSPEPLGDYFAGPNHVLPTGGTARFYSVLNVETFMKRTSIISYTRKALDEVSDDIIRLAETEGLEAHARAIRTRRDNI----
>UniRef50_C7NG13(3-435:439) Histidinol dehydrogenase n=2 Tax=Bacteria RepID=C7NG13_KYTSD   E=1e-147 s/c=1.21 id=51% cov=99%
-----VLDWNALDDSERTAALERPAQAVGEQVTAAVAEVLDAVRARGADAVVGYTERFDGVGREHLLLSEAEIDRAVEQVPDAVRAAIAQAAATLRTFHAPGALSPFAVDTAPGMRCERIVRPVRTVGLYVPAGSAPLPSTALMLGVPAVLAGCPEVVVCTPPtaqgTADPSVVAACVEVGIRRIAVVGGAQAVGAMAFGAGPIPRCDKIFGPGNSFVTEAKRQVAGMQGGPGIDLPAGPSEQLVIADAGANPVWVAADLLSQAEHGPDSQVVCVSDDRDLLEQVAAEVERQAAELPRAQIVAGALTASRLVLVDDLDQAVAVSNAYAPEHLILAVRAPRELLAGITAAGSIFLGDHTPESLGDYCSGTNHVLPTSGAARYTGGVNLASFQLSITVQEASPRALAQLGATAVTLARAEGLEAHARAVTRRVDASEAAA
>UniRef50_Q64EP7(23-419:419) Histidinol dehydrogenase n=2 Tax=environmental samples RepID=Q64EP7_9ARCH  E=1e-137 s/c=1.24 id=43% cov=88%
------------------------------AVMPLVNEIIAEVKSRGDRALLDYTEKFDGVKFlrqKDLEVRRSEIEDAKRNVDDHLLRSIEKASEAIKKFHYRQKRRVEVEKGEDkggteGMFIDNTYVPLDVVGAYVP---ASYFSTALMCVIPAKIAGVRNILVCTPPGKDGAVdsltlLAAAELAGATRIFKVGGAQAIAALAFGTETIPKVQKIVGPGNVYVTAAKM--AARAQGVEIDFPAGPSEIIIIADETANPLFIVADMLAQAEHGAKSKAVLLTDSARIAAEVERQI--------RTEAGDEEGEQNGIILGDDIGECIELANEYAPEHLEIMVREPKEVLKRIKNAGSVFVGDYSPVAAGDYATGANHVLPTAGYAKSFSGLDVHHFMRRMTVQWLDKEGLAKIKDVVVKMSRAEGMEKHAQSVEAR--------
>UniRef50_A3Q131(13-474:474) Histidinol dehydrogenase n=6 Tax=Mycobacterium RepID=A3Q131_MYCSJ   E=1e-134 s/c=1.04 id=38% cov=96%
-----------LSTAQLRSALPRGGVDV-DAVVPKVRPIVEAVAERGAEAALEYGEAFDGVRPASVRVPAERLASALAELDPDVRAALQVAIDRARAVHADQRRTDTTTTLAPGATVTERWVPLERVGLYVPGGNAVYPSSVVMNVVPAQTAGVDSLVIASPPQAdhgglpHPTILAAAALLGVDEVWAVGGAQAVALLAYGGTDIdgtgasgapgdgtgasgapgdgtgasgapgdvtelAPVDMITGPGNIYVTAAKRICRSQV---GIDAEAGPTEIAVLADHTADPVHVAADLISQAEHDEMAASVLVTTSPDLADAIDRELRRQLETTVHRERVSTALtgEQSAIVLVDDLDAGVRVVNAYAAEHLEIQTVDAAEVAGRIRSAGAIFVGPYAPVSLGDYCAGSNHVLPTAGCARHSSGLSVQTFLRGIHVVDYTEAALKDVSGYVITLAQAENLPAHGEAVRRRFES-----
>UniRef50_C9SQK1(338-699:699) Histidine biosynthesis trifunctional protein n=1 Tax=Verticillium albo-atrum VaMs.102 RepID=C9SQK1_VERA1  E=1e-128 s/c=1.27 id=47% cov=82%
------YDASKVSAAEVTEVLKRPSQKSPEAILNIVKPIIDEVRSGGDKAVLSYTHKFEKATSLTSPVLRAPFPEEAMKLSKESIKAIDISFENIRKFHAAQKEdKPLHVETMPGVVCSRMSRPIERVGLYIPGGTAVLPSTALMLGVPAMVAGCKKIVFASPPRADgsltPEIVYVAHKVGAESIVLAGGAQAVAALAYGTESVPKVDKILGPGNQFVTAAKMFVSNDTNaGVSIDMPAGPSE-----------------------------------------------------------------------VRDIDEAMRISNDYAPEHLILQLKNAPEVAQMVMNAGSIFIGEWTPESVGDYSAGVNHSLPTYGFAKQYSGVNLGSFVKHITSSNLTAEGLRNVGSAVMQLAKVEELEAHRRAVEIRLNYLDKK-
>UniRef50_Q1IKB6(16-411:415) Histidinol dehydrogenase n=1 Tax=Candidatus Koribacter versatilis Ellin345 RepID=Q1IKB6_ACIBL  E=1e-128 s/c=1.16 id=45% cov=90%
-------------------------MADASRVEPVVRKIVVDVRKNGDAALRRYASKLDGLgKTAALRVSTEELKSAWDATRSEFKQAIRAAAKNIERFARWQMPKSWTRDAGDGIELGQIIRPIESVGCYVPGGRYPLPSTVLMTVVPARVAGVERVVVVSPNP-ARETLAAAYLLGVGEFYRIGGAQAVAALAYGTESVERVAKIVGPGNIFVTTAKKLVAFD---CAIDMLAGPTEAAIVSERG-NARFIAADLVAQAEHDPETMVAFFTTSPSLADAVKKQVALLAA---KNTIARKALAtRGYIFVAQDIAQAMEAANQFASEHLTVD----EDLLETVSSAGSVFVGDYSAQSFGDYASGPNHVLPTGGLARVRGGLSVLDYVKIITVQKISRKGLRALAPIAETLAAAEGLVAHGQSVAIR--------
>UniRef50_Q0AP81(1-429:631) Histidinol dehydrogenase, Histidinol-phosphatase n=10 Tax=Bacteria RepID=Q0AP81_MARMM  E=1e-123 s/c=1.03 id=44% cov=97%
-----ILNWTDASPEARTRALTRPASSSSAGPAA--RDIVDAIRDQGDEAVRAYAKRLDGYAPGDFRVPEGVLKAARAALDPRDAEAIKAAADAVRRFHVQQGYRGYSVETWPGVTASRRATPVDTAALYVPAGSAPLVSSLIMLAIPAQLAGVPRIVVVAPPagdgGVNPALLAAADLLGLDEVYAIGGAQAIAALSFGAAGLPRADKIFGPGNAYVAAAKAYVSSLPGGPAVDLPAGPSEVMVIADETADPDLVASDLLSQAEHDPSAQVMLVCFDAATADRVTASVAKLLEDLPRAAIAREALAASAILVCDSVDDAIDIANIYAPEHLILQAESAERLLAGVRHAGSIFVGAWTPEAAGDYAAGPNHTLPTAGAARAHGGVSVESFQKTTTILRASEAGAVALAPTVERLAALEQLDAHGLAMRLRRER-----
>UniRef50_C6UN35(25-424:428) Histidinal/histidinol dehydrogenase n=1 Tax=Candidatus Hodgkinia cicadicola Dsem RepID=C6UN35_HODCD  E=1e-102 s/c=0.94 id=35% cov=91%
--------------------------RVSARVKAVAEKISQTVSAYADKALMAYNLRLDGCASRLLRFAP-DID--LETVDVKALFSLKLALDRVAALHSLQLPSSCCVRDALGAKLGFRWTPVSSVGVYVPGGTASYLSSVIMCCVPARIAGVGHISLATPYSKlanKPLFMACAKLCGVACVYPFGGAHAVAALSVGTRAVRKVDKIVGPGNAFVAAAKALAQGRV---GVDCLAGPSEAVIVADGVADAWTLAVDSLCQLEHASDALTAVVVSSAELASRVRANVALLVRSARRRRTAERSWSAGGVsVVCCCVADAAATVNALASEHVQACVLKPAKLLTKLTSAGAVFLGGGSPIVVGDYVGGTNHTLPTASGAKFASGLSVLDFMKRTYVTWLpTARPMLALAPACAACASAEGLSCHALASASRL-------
>UniRef50_A8A9G5(19-403:404) Histidinol dehydrogenase n=1 Tax=Ignicoccus hospitalis KIN4/I RepID=A8A9G5_IGNH4  E=2e-99 s/c=0.95 id=35% cov=84%
-----------------------------------VMPVVKEVKARGLEAVKKYNKAFDNYE-GCVSLSQEDFASYSK---ESLVSLFEEVLEQLSAFH-KQTAPKDSAFSSKGVRAVTLWRPVERLGAYVPGGLYPYPSTALMTAGVAKALGVKEVTVATPPKFAtSEVMASAFLAsKVDSVLAAGGAHGVSALAY----VAGAHKVVGPGGPYVQAAKLLVSVDVP---IDMIAGPTELAVIADSSADPEEVAYDMLAQAEHGPTSFALLVSTDEGLVLEVEKRVK-----------GEEVEGGLYATVVRDLEEAKRLVSELAPEHVSVYAETYEPPV-----AGAASF--KAPSPFLDYSAGPNHVLPTSGWAKARGPLGPVDFMRWTTLVEVFPEA-ADLLKLAAELARLEGMKYHAKAIEYKLSKI----
>UniRef50_C7H2J0(1-161:162) Histidinol dehydrogenase n=1 Tax=Faecalibacterium prausnitzii A2-165 RepID=C7H2J0_9FIRM  E=2e-51 s/c=1.27 id=33% cov=37%
-----LYNFDELRPEE---ILNR-DIRAEKNVEDVVDGIIAEVRARGDEALKEYALKFDGAKIDDLQVTQAEIDEAFANMDPYFLETLREAAANIESFHRQQVHKNFVINEKPGIVLGQKYTPIEKAGVYVPGGTAAYPSTVLMDVIPAKVAGVSEIVMTTPAGKDG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
