>ss_pred
CCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
>ss_conf
9888601220355656873014572788876407677754588589999999999999999988489998999999999999861200101366244311123334554246788999998445432104676333100366843348899999999999999999999999999999971798267100683642211999999999999999999999997443157540012386778800368999999998279986677520232153899999999998422399999999998278756503311588887868999997804899999999999898898898721583512631056588899999999999999999888529467999998875482508985755208999999999998099989999744799988999851889621014688887656519
>batch____
MSNNIRIEEDLLGTREVPADAYYGVHTLRAIENFYISNNKISDIPEFVRGMVMVKKAAAMANKELQTIPKSVANAIIAACDEVLNNGKCMDQFPVDVYQGGAGTSVNMNTNEVLANIGLELMGHQKGEYQYLNPNDHVNKCQSTNDAYPTGFRIAVYSSLIKLVDAINQLREGFERKAVEFQDILKMGRTQLQDAVPMTLGQEFRAFSILLKEEVKNIQRTAELLLEVNLGATAIGTGLNTPKEYSPLAVKKLAEVTGFPCVPAEDLIEATSDCGAYVMVHGALKRLAVKMSKICNDLRLLSSGPRAGLNEINLPELQAGSSIMPAKVNPVVPEVVNQVCFKVIGNDTTVTMAAEAGQLQLNVMEPVIGQAMFESVHILTNACYNLLEKCINGITANKEVCEGYVYNSIGIVTYLNPFIGHHNGDIVGKICAETGKSVREVVLERGLLTEAELDDIFSVQNLMHPAYKAKRYTDESEQ
>UniRef50_C5B2U6(104-571:573) Aspartate ammonia-lyase (Aspartase) n=123 Tax=Bacteria RepID=C5B2U6_METEA  E=1e-141 s/c=1.07 id=54% cov=98%
-----RSEHDLLGDGEVPADALWGIHTKRAVANFPITGVSVGHYPELVRALALVKQAAARSNHRLGYLPKGKAKIIEEACTLVATDPTYAESFVVDAIQGGAGTSTNMNANEVIANVGLRLMGKAPGDYAALHPNDDVNMAQSTNDAYPTALRLAVIFATQPLVKALDDLAYAFKSKAVEFADVLKMGRTQLQDAVPMTLGQEFDGFHATIKEDVARLTEIVGLFREVNLGATAIGTGINADPRYAALAVEELSRLSGQPMVLASNLIEATSDLGAFVLFSGVLKRVAVKLSKICNDLRLLSSGPRTGFGEIRLPAVQAGSSIMPGKVNPVIPEVVNQVAYMVIGHDLTVTLCAEGGQLQLNAFEPTIGYCVLSSLRMLTAAIDTLTKRCIDGIEADRERCRSLVQGSIGLVTALAPTLGYEASSRIARRALKENRAVADLVLEEGLLTEAQLNGLLELEAMTHPTRRQKAGT-----
>UniRef50_C0N7P0(4-449:453) Lyase superfamily n=1 Tax=Methylophaga thiooxidans DMS010 RepID=C0N7P0_9GAMM  E=2e-84 s/c=0.71 id=38% cov=93%
---------------HISQHAKWGKQTTIALKHFRVGTETFP--AELLHAYGMVKYCAAAVNQQQDLISSDIASAIMTAA-QALIKGELDQHFPLSVWQSGSGTQTNMNVNEVLANIA----NHNLASSNSVHANDHCNRSQSTNDSFPTALHIACTLLITReLLPALERLAQRFSEKADTWHSLLKSGRTHLQDATPITLGQEFSAFAFQIKQATTSIKQQLTVISELTIGGTAVGTGVNTVSGFSEAFCQQLNDLTGLQFQPTQNHFASQASHDAVVQLSGSLNTLATALNKIASDIRLLASGPRCGLAELHLPANEPGSSIMPGKVNPSQCEMLNMVCAQVMGNHTTITVAGAQGQLQLNTFKPVMAYNILQSLRLLTDAIVSFDTFCVQGIQANTPQLAAMMDKSLMLVTVLTPLIGYDKAAEIVKIAAQNNTTLREEVLNAGLLTQNEFDQLIRPEQMVSP-------------
>UniRef50_B9KWU0(2-458:481) Fumarate lyase n=1 Tax=Rhodobacter sphaeroides KD131 RepID=B9KWU0_RHOSK  E=1e-59 s/c=0.51 id=33% cov=95%
----VRLEEDAFGAVEILEGRLWGAQTQRALAVFGASGPRLPVA--VIRAFAAQKAAAARANLALGMLDAERAGLILAAC-ERLGQGAFDDHFPLPVWQTGSGTQTNMNVNEVLANAANMAAGQGPGTRAPVHPNDHVNRSQSSNDSFPTVMQIaAVAEARGRLAPELDRMAVALEERAAAFAGIPRLGRTHLNDAVPVPLSQGFAASAAEMRRSARRLSAALDELLALPQGGTAAGSGLNAPEGFDRAFCAALSEATGEAFRPAAVKVEGMAGHDALLGLSAVCEALAVALTRLCNDVRHLAAGPHAGTGELSLPDDGLTSSIMPGKRNATLAEALVQVCQHVAGCHETVSRAAASGVWDLNVSKPVLIHALLGAMEALAQGMEGFRLHCLAGIEPRRARLADNLARSMMAATALTPRLGYDRVAGLIRRAEAQGLTLRAACLAEGILGPEAFDRLVDPERM----------------
>UniRef50_B3T9V2(8-433:489) Putative Lyase n=1 Tax=uncultured marine microorganism HF4000_APKG7H23 RepID=B3T9V2_9ZZZZ  E=4e-06 s/c=0.13 id=27% cov=85%
----------------------YTTHTFQSASHYTVSVGYDRRLASYdIRA--SVAHAQMLARQEI--IPQSDSDAIVRGLGEVhqeMEDGT----FPWrDELE-----DVHMNIERRLH----ELIG---------EPAARLPTARSRNDQVATATRLYVRDAIEATMARVHRLQGTLLDLAEAHATVLMPGYTHLQRAQPVLLAHHLLAYVEMLE---RDTGRLADCLSRANvlpLGSGALA-GV-------PYAIDRefLARELGFETVSANSM-DAVSDRDYLVELLASASICMMHCSRMAEELVLWSSQE---FGFIRLgDEWITGSSMMPQKRNPDFAELARGKTGRVYGHLVGLLTVLKGLPLSYNRDLQEDKEALFDTVETL-DATLEVFAGMLGSVEVNAERMRSAAEDGSLLATDLAdylvskgvPFRTAHAA-VRGlcELAAQDGRPLQELTLEEYRRFSPAFDaDVFQLTALTSVAARA---------
>UniRef50_P08417(24-487:488) Fumarate hydratase, mitochondrial n=1225 Tax=cellular organisms RepID=FUMH_YEAST  E=0 s/c=1.53 id=38% cov=97%
MNSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADEV-ASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGGKIGSKQ-VHPNNHCNQSQSSNDTFPTVMHIAASLQIQnELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDAASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGP-------------
>UniRef50_D2LRV9(7-473:477) Aspartate ammonia-lyase n=2 Tax=Bacillus RepID=D2LRV9_BACS4   E=0 s/c=1.46 id=50% cov=97%
-----RTERDLMGEKEIPADAYYGIQTVRAKENFPITGY--PPHKELIRAFGYVKKAAAKANADVGVLNKNIAEAIIKASDEVIE-GKLNDHFIVDSIQGGAGTSFNMNANEVIANRAIEILGGKKGDYIKVSPNTHVNMAQSTNDTFPTAIHIACLHLSSGLIRSLNDLIESMRKKEREFDDVIKMGRTHLQDAVPIRLGQEFGSYRRLLSRDLGRIKRSVDLLYEVNMGATAVGTGLNAMPEYIEKVTEHLAAMTSMPLHRAEDLVDATQNTDAYTQLSSAMKILAINLSKIANDLRLMSSGPRTGINEINLPPRQAGSSIMPGKVNPVMCEVINQISFQVIGNDHTISLASEAGQLELNVMEPVLVFNLLQSFTILQNGMKVFRDFAIEGMTANIEHCKELVERSVGIITAINPHVGYETAARVAKEAITTNRPVREICHERGLLSEEELERILDPNEMTNPGIAARELI-----
>UniRef50_Q59200(54-525:526) Aspartate ammonia-lyase n=176 Tax=Bacteria RepID=ASPA_CORGL   E=0 s/c=1.43 id=64% cov=99%
--KKFRIESDLLGELQIPSHAYYGVHTLRAVDNFQISRTTINHVPDFIRGMVQVKKAAALANRRLHTLPAQKAEAIVWACDQILIEERCMDQFPIDVFQGGAGTSLNMNTNEVVANLALEFLGHEKGEYHILHPMDDVNMSQSTNDSYPTGFRLGIYAGLQTLIAEIDELQVAFRHKGNEFVDIIKMGRTQLQDAVPMSLGEEFRAFAHNLAEEQTVLREAANRLLEVNLGATAIGTGVNTPAGYRHQVVAALSEVTGLELKSARDLIEATSDTGAYVHAHSAIKRAAMKLSKICNDLRLLSSGPRAGLNEINLPPRQAGSSIMPAKVNPVIPEVVNQVCFKVFGNDLTVTMAAEAGQLQLNVMEPVIGESLFQSLRILGNAAKTLREKCVVGITANADVCRAYVDNSIGIITYLNPFLGHDIGDQIGKEAAETGRPVRELILEKKLMDEKTLEAVLSKENLMHPMFRGRLYLE----
>UniRef50_B0WME6(42-480:481) Aspartate ammonia lyase n=1 Tax=Culex quinquefasciatus RepID=B0WME6_CULQU  E=0 s/c=1.52 id=39% cov=92%
---GFRTESDTFGELKVPNDKYYGAQTVRSTMNFPIGGPTERMPQPVITAMGILKKAAALVNKEYG-LDPKVADAIALAADDVISGKLYDDHFPLVIWQTGSGTQSNMNVNEVISNRAIELMGGTLGSKTPVHPNDHVNKSQSSNDTFPTAIHISVARELTGnLKPAIQTLHDALKAKSDEFKDIIKIGRTHTQDAVPLTLGQEFSGYVQQMEFALQRIEACLPRVYMLALGGTAVGTGLNTRIGFAEKCAAKISELTGLPFVTAPNKFEALAARDAMVEVSGCLNTIAVSCMKIANDIRFLGSGPRCGLGELSLPENEPGSSIMPGKVNPTQCEAMTMVCAQVMGNNVAVTVGGSN-----------------------ADSARTFSKNCVVGIQANRANIDKIMNESLMLVTALNPHIGYDKAAKIAKTAHKEGTTLKQAALKLGYLNEQQFNEWVRPENMLGP-------------
>UniRef50_Q3A7R0(4-466:468) Fumarase n=14 Tax=cellular organisms RepID=Q3A7R0_PELCD   E=0 s/c=1.44 id=42% cov=97%
-----RIEKDSMGTMEVPASALYGAQTARALANFPISGQRFSRP--FIHALGLIKRYAAQANLELGMLDEQRATAIMQAADEVI-NGELDEHFVLDIFQTGSGTSTNMNANEVIANRAAQILGQAAGSRA-VHPNDHVNLGQSSNDVIPTAMHIAAALEIRNsLVKALFDMQEALGEKALAFNDIIKIGRTHLQDATPVRLGQVFSGYARQLALAIRGIERAQDDLLELALGGTAVGTGLNAHPQFATRAIAAISDQTGLEFREASNHFEAQAAKDAVVAASGALKRGACALFKIANDIRLLGSGPRCGIGELQLPPVQPGSSIMPGKVNPVMAESLMQVCAQVIGNDAAIALGGLSGNFELNVMMPVMAHNLLQSITLLTNASTQFTRRCLQGLEADRARCESLVEQSLAMCTALAPVIGYDQAADIAKQAFASGRTVREVALEQQVLPEEKLAQVLDPRPMTEPGIPGK--------
>UniRef50_Q1IN60(3-472:476) Fumarase n=10 Tax=Bacteria RepID=Q1IN60_ACIBL   E=0 s/c=1.38 id=46% cov=98%
-----RQEKDSLGYKDVPADAYYGIQTARAVENYPISG--MRAHATLIRAIAMVKQAAAEANLELDLIDARVAEALILAAKE-MQEGRWDDQFVVDVFQAGAGVSFHINANEVIANRAEELTGGKLGEYKIVHPNDHVNYGQSTNDVFPTAMRLATLLELEKLYPVLDGLASAFGAKGKEFHDILKSGRTHMQDAVPMRLGQEFAAYAGAVRRAEKSVREQSELLRELGLGGSAVGTGINTHPEYREKAIRNLARISGQKLVVADDMRYAMQSNLAMASVSSALRNLSLEIIRISNDLRLIASGPNTGLAEINLPALQPGSSIMPGKINPVMPELAAMVCFQVIGNDTAVAFAVQAGQLELNVMMPTMAYSVLQSVTILTNMVRVFTEKCVIGITANAKRNEMYAQSTVSLATALNPYIGYAKAAEIAKESVATGRTIIEIAREKKYLSEEQIKEILDPAQMTEPRLPSEAAKDRDK-
>UniRef50_A7I3J5(3-462:469) Aspartate ammonia-lyase (Aspartase) n=1 Tax=Campylobacter hominis ATCC BAA-381 RepID=A7I3J5_CAMHC  E=1e-179 s/c=1.37 id=49% cov=96%
-----RKEHDFIGELEISDDVYYGVQTFRALENFHMTGRRIKDYPFFVKAFAQIKKAAALANKEVGVLEAKKADAIAKAADRVIA-GEFLDQFVVDMVQGGAGTSTNMNANEVITNVALEMMGHKKGEYKYLHPNDNTNLGQSTNDTYPSSIKVATYAKMTDLLKAMEVLKKELEAKAKEYKDMIKMGRTELEDAVPTTLGNSFNAFASYIKSDIAAVKNARELMTYLNMGATAIGTGINCHPDYKFVVEKKLSEITGTEFKAAPDFIAATQDTADFVQVSGALKTAAVRLSKIANDLRLMNSGPRCGLGEIDLPKMQPGSSIMPGKVNPVIAEVVGEACYEVIGNDVTIMLCSERGEFELNAFEPGIAYALFNSLVILENAYITLANKAIKDIKAKPEACLKAVLNSVGIVTAFNPVIGYENSASIAKEALNTGKSVGEIAIERGLLTKEEVDKLLDPKSMLNP-------------
>UniRef50_Q7U8I1(1-465:465) Fumarate hydratase class II n=6 Tax=Bacteria RepID=FUMC_SYNPX   E=1e-179 s/c=1.35 id=36% cov=97%
MGQPMRQEHDSIGGVDVPAAALWGAQTQRSLNNFAIGHQKIP--AELIHALARIKQCCAAVNGRHGLLNDQQVALIERA-GQAIQTGQQDDHFPLSVWQTGSGTQTNMNVNEVISNLAAQESGENLGSHRPLHPNDHINRSQSTNDVFPAAIHVAAALQLqQELLPELKRLIASLDAKAVAWQDIIKIGRTHLQDAVPLRLGDEVSAWRDRLSDGAHWLTTAHQDLLALPLGGTAVGSGLNTPDRFAHEVCAELASRTGSDFQPADNLFAVMAGHDSLVQTMAQLRRLAVTLLTIANDIRLLACGPRAGLGELLLPANEPGSSIMPGKVNPTQCEAMAMVCTQVIGMDAAVAAAGAGGHLQMNVYKPLIGYNLIEGIRLLQDACRCFRLNLLTGMEADRDRIAFYVERSLMLVTALTPEIGYEKACAIAQHAHRDGLTLREAAMQSGAITDERFDQLIDPAAMASP-------------
>UniRef50_B4SPD1(6-462:475) Fumarate lyase n=7 Tax=Bacteria RepID=B4SPD1_STRM5   E=1e-178 s/c=1.37 id=40% cov=96%
-SKGFRIEHDSMGELQVPADALWGAQTQRAVQNFPVSGQRMPR--GFIRALGLVKGAAAGVNAELGHLPKNVAKAIQTAAAEV-ATGEWDAHFPIDVYQTGSGTSSNMNANEVIATLANRA---GKAGKTSVHPNDHVNQGQSSNDVIPTALRVsAVLATHEQLLPALVHLRKTLDKKGRSLRKVVKTGRTHLMDAMPLTFEQEFGAWSAQLASAQERIEDSLKRVRRLPLGGTAIGTGINADPRFGTQVAKALKQQTGFKFDSAENKFEGLAAQDDAVELSGQLNALAVALIKIANDLRWMNAGPLAGLGEIELPALQPGSSIMPGKVNPVIPEATVMACAQVIGHHTAITVAGQTGNFQLNVTLPLIAVNLLDGIGLLANVSTLLADSAIAGLKVREDRVAEALARNPILVTALNPIIGYEKAAAIAKRAYKEQRPVLDVALEDSGLAEAELRRLLDPTALT---------------
>UniRef50_D2UDT9(1-467:473) Probable fumarate hydratase class II (Fumarase c) protein n=1 Tax=Xanthomonas albilineans RepID=D2UDT9_XANAL  E=1e-178 s/c=1.34 id=39% cov=98%
MSEKYRVEHDSMGELQVPIDALWGAQTQRAVQNFPISGRPMPR--GFIRALGLIKAAAAGVNAELELLPKAVAKAIQAAALEV-ADGRHDAQFPVDIYQTGSGTSSNMNANEVIATLASRAAKSGAKATSAVHPNDHVNLGQSSNDVVPTAIRVsALLAAQEQLLPALKHLRKVIDKRARQLERVVKTGRTHLMDAMPLTFGQEFGAWSAQLASAQERVSDSLKRLRRLPLGGTAIGTGINADPRFGGKVAKALSTLTDCKFESADNKFEGLAAQDDAVELSGQLNALAVALIKIANDLRWMNAGPLAGLGEIELPALQPGSSIMPGKVNPVIPEATVMVCAQVIGHHTAITVAGQTGNFQLNVTLPLIAANLLESIQLLSNVSRRLADSAIAGLRVREERVREALERNPILVTALNPIIGYEKAAAIAKRAYKENRPVLDVAAEDSGLSKDALRRLLDPAALTEGGIHA---------
>UniRef50_C9M5I1(2-456:469) Fumarate hydratase, class II n=1 Tax=Jonquetella anthropi E3_33 E1 RepID=C9M5I1_9BACT  E=1e-175 s/c=1.36 id=36% cov=95%
---EYRMEHDTLGSVEVPANRLWGAQTQRSLQNFPIGNESDRMPREIIKALLIIKAACAKINRQFGLVPQDIADAVASAALRLYENTPWED-FPLQVWQTGSGTQTNMNVNEVIARVASDAIGR------PVHPNDHVNRSQSTNDVFPSAVHLAsLLLAERRLLPAGENLAKRLESKARRYSRLIKIGRTHMQDATPVTLGQEIGGWAASVRRNLGMIAMSLELLRPLALGGTAVGTGLNAPANFGLLVATELTEFLGTRILSERNKFHALSSRGELCAFHGVVRTLAADVFKIACDVRLLASGPRCGFGELVLPANEPGSSIMPGKVNPTQCEAITQIAIQIMANDVAVSIASSQGTLELNTYMPLLARNVLSSCQLLADGMQSFAERCIVGITANEKQISRFVGQSLMVATALTPVLGYEKVAALAKLAYENDSSIRETVLADGALTAEQYDQLMMMDRLVG--------------
>UniRef50_Q010D6(82-518:524) Fumarase (ISS) n=3 Tax=cellular organisms RepID=Q010D6_OSTTA   E=1e-174 s/c=1.40 id=38% cov=91%
-----RRESDTMGVVDVPMHKLWGAQTQRSLENFKIGGEKMPI--AIVRSLAIVKYAAATVNEREGRL--------LGSCED-----HWMNTFPLVRVPNRIGTQTNMNLNEVICN-------------SPIHPNDHVNMSQSSNDTFPTAMSIATAHEVqERLIPALKMLQEALHVKVLAWGDIVKIGRTHLQDAVPITLAQEFSGYEQQVKNSLLRAKGALVHLLELAIGGTAVGTGLNAPPRFGENMAAEISMLTGLPFVSAPNKFEALAAHDAQSTLSGMLKTIAISLLKIANDIRLLGSGPRAGLGELCLPENEPGSSIMPGKVNPTQCESLMQVCAQVIGNDLAVTIGGSAsSHFELNVAKPLIAHNNLNSIALLSDSLESFTKNCVVGIEPNMERIDALMRSSLMLVTSLVPKIGYDKAAKISKKAHAEGLTLREAGVQLGLLTNEQFDEWIRPDEMTRPE------------
>UniRef50_Q72B70(9-470:470) Aspartate ammonia-lyase, putative n=7 Tax=Bacteria RepID=Q72B70_DESVH  E=1e-171 s/c=1.31 id=43% cov=97%
----IRIEHDLLGDCAVPRTALHGAHTQRALSNVALSGRPLH--PEIIRAFGAVKRACARTNMNLGHLSREVAEAIIMACDE-LEDGGLGEHIVVDALQGGAGTSANMNVNEVLANRAEEMLGGTRGQYQLVDPLAHVNLHQSTNDVFPTAVRIAALRLLARLEPAIAALQSAFQTHEASFAQVVRLGRTQLQDAVPMTFGAACGAWAEALSRDRWRVFKCSERLRVVNLGGTAIGTGIAAPRSYILSVVDRLREDTGLPLARAENLMDATQNVDAFVEVSGILKAHASNLLKLSSDLRLLASGPGGGIGEVVLPPVQAGSSIMPGKVNPVVCETVAQAAMQATANDLAITLSAQHGQLELNAFMPLIADALLHGIELLTNACDLFRTRCVEGLHPDTETCARHVSTSTATLTALVPEIGYAAASEMARHMREHGTDVFGAAKATGLIDEDRLARLLSPERLVALGYRG---------
>UniRef50_Q043Y6(4-459:468) Fumarase n=61 Tax=Bacilli RepID=Q043Y6_LACGA   E=1e-170 s/c=1.32 id=37% cov=95%
--KGYRVESDTLGPVEIPEKALWGPQTQRSKDNFHTGAL---MPIGIIRALLQIKLAAAQANIEAGTETEEKGRAIIEAIHQLLDlnNEELQPYFPLHVYQTGSGTQTNMNVNEVVANLANQ-----NHPGLNILPNDDVNMGQSSNDTFPTAMNLVATQALDDLKPSVKHLIKELKAKQDEYWTTVKVGRTHLQDAVPLTFGQELSGYVAALNHDLAYINELEETLYELPIGGTAVGTGLNAAPGMAEDISERLSRKYGHQFDVKTNKFFGLANHSGLNVVHGALKALAADMFKIAQDIRFLGSGPRAGLGELNLPANEPGSSIMPGKVNPTQAEAVTMACLRVFGNDTTITMAASQGNFEMNVFKLVMIAAFLESANVLSGTISSFANKMIHGMTVNKERMAKDVTDSLMTVTALSPHIGYHEAATIAQTAAKENTTLRTAALKSGLVTKEQYDKWMKPITMTN--------------
>UniRef50_C5CDV4(1-463:464) Fumarate lyase n=1 Tax=Kosmotoga olearia TBF 19.5.1 RepID=C5CDV4_KOSOT  E=1e-163 s/c=1.25 id=41% cov=91%
----MRIEKDALGKLEIPDDVYWGIHTARALKNFPSTGEKIDE--EFIRCYGYIKKSAAFLNKKLGFLETKIADAVIQAADELI-SGSLMKWVVVDPLCGGAGTSINMNINEVIANRATEILGGKLGEY-IVHPLDHVNLHQSTNDTFPTAGKMATIALLKQLVENVTNLQDSLQKKEAEYRKMIKPARTQLMDAVPISLGQEFGAMAEAISRDRWRLYKVEERIRMVNLGGTAVGTGIAADRKYVLSIVETLRTVSGIKIAKAENLIDATQNMDVFAEIHGLLKALATNLIKISNDIRLLGSGPGSAIGEIKLPKLQAGSSIMPGKINPVIPEYVVQLSLAVLGHDAIINFAVSSGNLELNAFVPEIIHYTLKSLRFLTIAANSLA-NYILKIEANPEKMRENLLSSSAILTPLITTYGYDKVQEWIELSSKTGKNLWEIVKDS---------------------------------
>UniRef50_Q978Q5(1-450:457) Fumarase n=4 Tax=Thermoplasmatales RepID=Q978Q5_THEVO   E=1e-159 s/c=1.26 id=43% cov=94%
----MRTERDVIGEIQLEDTVFYGINTARAKENFRITG--LTSDSDHIVSIAQIKKAAAMANAEAGALDKEKAEFIEKACDEII-SGRYHDQFVIDVYQAGAGTSFNMNANEVIANVALTLMGKNKGDYSVIHPNDHVNMSQSTNDVYPTMMRLTVTKKVKKLKEAISDLIESLEKKSKELRGIPKPGRTHLQDAAPVTVGLEFSAYAYAIKKDRDEITDALDYIMELNIGGTAVGTGINTSKNYQENVVKHIAEITRENFRKSSNLMGIMQFMTDFSRVMNAVTNLALDIEKIANDIRLLYSGPGTGIHEIIIPAVQQGSSIMPGKINPSIAEAMNMICHSVIGAQQAVNMSVQAGQLELNVMMPNIDYELTRSIDIMRNGLIMFKEKLIDGIKANVNTCREHLANSFGSAALLNPYLGYDNVAKIVREAVETGKSIKSLVLATGKITEEQYMKIM---------------------
>UniRef50_B8DQ99(44-522:528) Fumarate hydratase, class II n=3 Tax=cellular organisms RepID=B8DQ99_DESVM  E=1e-159 s/c=1.18 id=38% cov=96%
-----RLERDSMGLVEVEQGRLWGAQTQRSLDNFRIG--TDRMPLAVVHALARIKKAAALVNRDLGLLPppppgqpdqpglPHMAEAIARAADEVLA-GQHDDHFPLSVWQTGSGTQTNMNVNEVLANRATQLLaeaahaaasGGHPHIHPPIHPNDHVNRCQSSNDAFPaAMHLAAALALRDDLLPGVRHLRDALRAKAAACADIVKIGRTHLQDAVPLTLGDEMSGWAAQLDACLEGLDAAMPHLCRLALGGTAVGTGLNAHPAFAPRAIALLADMTGLPLVPAPNPFAALAAHDGLVLTSGALRALATALLKIANDVRWLASGPRCGIGELRLPENEPGSSIMPGKVNPTQCEALTMVAVQVMGLDVAVGMAGSQGNFELNVFKPLIIHNVLTSMRLLADGCRSFADHAVAGMQPDRAGIAAHVGRSLMLVTALAPVVGYDRAAQAAHRAHAQGITLREACLEMQLLDGAAFDAAVDPLRMARP-------------
>UniRef50_A1B109(8-455:455) Aspartate ammonia-lyase n=1 Tax=Paracoccus denitrificans PD1222 RepID=A1B109_PARDP  E=1e-142 s/c=1.13 id=43% cov=90%
-----RIESDELGSRRLPGEALYGINTLRAAENFPVSGMKIGSLAPLIRAMALTKKAAAAANYRLGKLSARKAEVIGRVCDELMA-GQHAGHFVIDVFQGGGGTSSHMNLNEVIANRGLELMGRACGQYEHLHPIRDVNRSQSTTDVHATALRIALMQGAPGLERALLALAEAFAGKAQEFGGILKLARTHLQDAAPMTLGEEFHAFSTALRHEAARIWPASQGLAGLNLGGTMVGTGLAAQPDFAETVIAELQRLTELPLRRDDDLVCAAWNSAGLVQFSSLLRGIAVTLSKIANDLRLLSSGPRGGIGEISLPAVQPGSPLIAGKVNPVIPEMVSQVAFHVAGADVAVGMAAEAGQLQRNAFEPLMAHCLLTSLGMIESAARIFAERCVQDIRAAPEACAGNLSAPGTLAAGLVPLVGRAAAADIS-EAVARG-------------------------------------------
>UniRef50_C9QH62(3-442:446) Aspartate ammonia-lyase n=1 Tax=Vibrio orientalis CIP 102891 RepID=C9QH62_VIBOR  E=1e-125 s/c=1.02 id=29% cov=92%
----YRIEVDNIGEVRIPVLLPYGAQTQRALNLYPVDNQKtLGDYASLINAVLRIKLASARVNREIGEMDPVLSLNVENTCQSILENYQ-RELFPVHAFHGGGGISVNMNVNEVVANIVNhSYYAQPYGTYSPAHPNDAINMNHSTSDCLQTASHLAAIEALDRLDTTTERLIYALEYLMANHSDSSKLARTCMQDAVTIEFKQFWGGYLASLRTYQMHLKACRNDLQAVNLSGNIIGRSGDCSTAYAERCIAVLSDVIGIELRKSDNLFQSSQSFDAQIHCVSQVENLAGFIIKIAKDLRLMSSGPEGGLSEITLPAVQAGSSAMPGKVNPTIPEFAIQSAMQAQGHCYSSKQAHIHGELDYNPWGMLLITNLLDAIDHLEKGISVLTEKCIFGIEVNSETQSRNESALVPLVVRVKSKIGYKATLDHVKEA-KNSTELKETLQE----------------------------------
>UniRef50_B4RI44(41-454:457) Fumarate hydratase, class II n=1 Tax=Phenylobacterium zucineum HLK1 RepID=B4RI44_PHEZH  E=1e-120 s/c=1.05 id=30% cov=87%
----------------------------------------EPPPPALIRALGEVRAAAALANRDCGALDQARSEALARAALQV--SVQPPDAWSRPLWQDGGGAGLAYPLDAAILEVAR--------GHADIRPED-VRRHQCV-DAVQTALHMAALRLWEtGLSPALAHLTGLLEQKAAAWSDLIKIGRTHLQDAAPLTLGQEVSGWLQQVRNGRSRLSAAAEDLLAVPFGQGCVGTGAGVPAGFAASAIRRLAERTGLALRPSPDALADLTGPGRIAFFHAALATLATALFKISSDVRLLASGPAAGFNELRLPETGLPCSSLPGKTNPDAAEALAQVCVQVIGADGAVSLAASQGQFESNGFLPLLAFNVLRSATLLADAIRVFADHGVAGLKPRTDVLAFNVAQSVMLVTALAPHIGYDVAAKIARDAYQRKVSLREAALASGVVDAETYERLVRPERMLGP-------------
>UniRef50_C1B6A8(27-424:457) Putative aspartate ammonia-lyase n=1 Tax=Rhodococcus opacus B4 RepID=C1B6A8_RHOOB  E=1e-108 s/c=0.99 id=41% cov=77%
---------------------LYGEQTTLSLNNFPGPGRTFGDVPAFVRNYARVKLAAAQANHALGVLDSIRRDAIVTACREI-ASGDHPTQFPSALLLGGGGTTTNMNVNEVIAARATLLAG------VTVHPNDHVNASQSTNDSYPTAMALTVLELAEPPLEALDELVTALENKATEFDDTRHLGRTCLRDAVSLSAGQSHRAQAAAIRRTADGLRVAVGAMRSVPLGATAVGTGLGAPDGYRELAITELAAASGLDLRPAPDLFDALAHLDPYADIAAAGARTGMTMAKVAADIRLLSSGPTGGFGDLTIPAVQAGSSIMPAKVNPAIPEYVMQLSYRIRGAAHTIEFAVSAGELELNVMEPVIVDALVTIFDDLTAAAISFARRCVNGIT-----------------------------------------------------------------------------------
>UniRef50_A7GZH7(1-272:285) Ribose-phosphate pyrophosphokinase n=4 Tax=Proteobacteria RepID=A7GZH7_CAMC5  E=2e-90 s/c=1.23 id=40% cov=57%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTFGQYFSGYVSFVKRMEAKFKALLDEASELPLGATAIGTSLSVHEGYLSKVYEKLNLVTGKKFKMEENLFDGLQNADFYIEISANLKRLATTLSKIATDFRILSSGPRAGINELNLPAVQPGSSIMPGKVNPVIPELINQIGYQICGNDVAITMAVEGGELDLNVWEPVIIKNLCESFKLLQNGLIIFANKCIDGLEPNEQICAKFANDSTALSTIISSIFGYKVGTKVARKAFEEDKSVKEVVLELKILKPDEADEVLDTFVMIYPQKSA---------
>UniRef50_O27580(5-447:449) Adenylosuccinate lyase n=14 Tax=Euryarchaeota RepID=PUR8_METTH   E=1e-86 s/c=0.73 id=24% cov=89%
-----------------PVEFRYGTPEMRVI---WEAENKL-------QKMLDVEAALAQAEGELGIIPAEAASEIVrKASTEFVTLERVNE--------------IERDTKHDIASLVKALAEQCEGD-----AGEYVHFGATSNDIVDTSNSLLLRDSISVLRDKLTRVLEVLLALADENRDRVCIGRTHGQHALPTTYGMKFAIWADEIHRQLERLDACSERLC-VGMMTGAVGTTAALGEE-GLEVHERVSEILGLRPVLISNQVVQRDNHAEFIMV---LANIATTLDKIALEIRNLQRTEIMEVGEKFDPEKQVGSSTMPHKMNPITAERICGIA-RVIRSYVVAALENNPLWHERDLTNSSSERIILPEACILTDYILKLTLDVLcnlvfypENIKRNLEFTGGLIMAERLMAELTRRGMGRQTAYAAVRqcaiEASRTGRSLRDVVLERSeimdYLTVEDLEEIMNPETYIGSARRmVERVLEESQK
>UniRef50_O66856(90-422:437) Adenylosuccinate lyase n=361 Tax=cellular organisms RepID=PUR8_AQUAE  E=1e-43 s/c=0.54 id=23% cov=66%
----------------------------------------------------------------------------------------------------------------------------------------YIHMGLTSSDVVDTALALLIREAIDIILKDIDKVMEEIKRLAFEHKDTLMMGRTHGVHAEPYTFGLKMCVWYDEMRRQKERLLFARENVLYGKISG-AVGTYSNIPPE-----VEKLAlEELGLKIEPASTQIV---HRDRHAQLLTTLGLIASSLEKFATEIRHLQ---RTEVLEVLEPftKGQRGSSAMPHKKNPIHSERICGLA-RVIRANSIPAMEDVVLWHERDISHSSVERVILPDSFIALDYILNLFYEILKGLVVNKERMRKNMELSKGLYASskilvlltqkgLSRDYAYDIVQRCAMKAWESDKTFKETLLEDpevtKYLTEEEIEKALDPWEFL---------------
>UniRef50_C9KK95(18-430:475) Argininosuccinate lyase n=1 Tax=Mitsuokella multacida DSM 20544 RepID=C9KK95_9FIRM  E=5e-43 s/c=0.43 id=21% cov=79%
---------------------------------------------------GSIAHATMLA--KCGIITDEDRDKIVAGLKDILQKiEKGNFEFSVDL------EDIHMN----IEKRLTDAIGEAGG---------RLHTARSRNDQVALDTHMYVRREIVAVQKEIENLQRALVETAEKYSDVIMPGYTHLQRAQPILFSHHLLAYFGMLSRDFARFEGVYKRADIMPLGAGALaGTTFPIDREFVQK---------QLNFDSIyTNSLDAVSDRDYIMEFLAAASILMVHLSRLSEETILWCSRE---FHFVELDDAHcTGSSMMPQKKNPDVSELVRGKTGRVIGHLMAMLTTVKGLPLAYNKDLQEDKEGIFDAIDTVKFSLAVYAQ-LIRGMKVRKDVMKKAVTEDFSNATDLADYLvkkGmpFRKAHAVSGQAvhdcIEKGIYLEDMSLEDfqklSPLFGADIKEAISPET-----------------
>UniRef50_C1TNB5(10-406:457) Argininosuccinate lyase n=1 Tax=Dethiosulfovibrio peptidovorans DSM 11002 RepID=C1TNB5_9BACT  E=4e-42 s/c=0.44 id=22% cov=71%
---------------------------------------------------GSLAHAEMLAKQDL--ISQEELEAIRSGFQEIMDEIERGDFIPDESLE-----DVHMNLE----HRLTEKIG---------DAGARLHTGRSRNDQVGTTMRLYVKDVLCQVKSGMIDLMDALLNRAESHRETIVPGYTHLQQAQPVSMGHLWMAYFQSFSRDLKRLEFAMDEADECPLGCGALaGSTLPLDREYT-------AEALGFS-RLCENSMDGVGQRDYIFDALSFSTMFAVHCSRMAEDLIIYSS---AEFGWLKLPdAFCTGSSMMPQKKNPDVLELVRGRTGQMIGHLVDILATLKGLPMTYDRDLQEDKRGLFSSFDVLSHVLGVLPS-LVRAIEVDADRAAESFADGLALATDVAEYL-----------------------------------------------------------
>UniRef50_B1ZZY3(22-465:470) Argininosuccinate lyase n=6 Tax=Verrucomicrobia RepID=B1ZZY3_OPITP   E=4e-42 s/c=0.39 id=25% cov=69%
------------------------------------------------------------------------------------------------------------------------------------------HTARSRNDQVATDMRLWFKHACGVLAQKIAGAQRALLEVATANRTVLIPGYTHLQRAQPVFLAHHLFAWIEMLDRDGARFRDVAEHANWCPLGAGAIaGTTLPIDREFTARALGFL-DAKGRPQVT-QNSMDTVADRDLFIEFAAACALFGVHVSRIAEDLILWSS---AEFKFAELPdAFCTGSSLMPQKKNPDACELLRGKSARLQGNLHTLLTLTKGLPLTYNRDLQEDKPPVFDSFDQ-TALCADVLAGTVTGMKIQVERCAAAVSDPALLATDLADYLvakgvpfreAHHAVGAVVRLAEKNNAALNQIPTEEMKkihpAFEEDWAEVFDLGRalakrsgtgMPGPGALAKQFK-----
>UniRef50_A9WJR8(105-428:461) Argininosuccinate lyase n=5 Tax=Bacteria RepID=ARLY_CHLAA   E=6e-42 s/c=0.54 id=22% cov=65%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNDQVATDMRLYTIGIARQLDRRLRDLQLALLAQAEQHTATVMPGYTHLQRAQPITFGHWCLAYVEMFARDRSRLNDAIRRMRVLPLGAGALaGNSLGVER-------ERLTELLDEFDELSANSLDAVSDRDFVAEVLFACALIGVHLSRLAEDVILYAS---AEFGFLELaDAYSTGSSLMPQKKNPDSMELLRGKSGRLLGNLVALLTVLKGLPLTYNKDMQEDKEPLFDSFDTLDLGLQV-AAAAIATMTVRPERMAAALDD-AMLATDLAdelvrrgvPFrVAHSKVGQLVQRALTRGVSLRQLPLADYQAVEPSLDaSIYDVFDM----------------
>UniRef50_D1SP80(84-468:521) Argininosuccinate lyase n=1 Tax=Methanocaldococcus sp. FS406-22 RepID=D1SP80_9EURY  E=3e-41 s/c=0.45 id=23% cov=77%
---------------------------------------------------------------EQGIIKKDDAKKIIEGLKEIYKKG--MENLNLDP----SLDDIHM----VIENELIKKLGEDVAGRM--------HTGRSRNDEVATDLRIALREKVLMIAKSLIEMLKDILELAEEHKETLTVGYTHLQHAQPTTFAHHLLSYVSAIERDILRLLDAYKRINISPLGCGAMATT-----GFKIN-RDRTKELLGFD-ALIENSMDGVSARDFIVETMADLAILGTNLSKICEEL-ILFSTYEFGTVEI---ANEfcSTSSIMPQKKNPDVAEIARAKLSKLNGNLVTALTILKALPNTYNRDLQEISPHLWDSVYTTIDTIK-MVHGMLKTIKVNKERMKELANANYSTATELADTLVRETgipfrtahgiVGEVVRRSIEEKKDMIEIiyeVLEKYNLkvGDEKIKKALDPYE-----------------
>UniRef50_Q49YV3(88-415:431) Adenylosuccinate lyase n=82 Tax=Bacteria RepID=PUR8_STAS1   E=2e-40 s/c=0.52 id=20% cov=66%
-----------------------------------------------------------------------------------------------------------------------------------------VHYGLTSTDVVDTALSYVIKQANEIIKKDLERFIDVLAQKAKDYKYTLMMGRTHGVHAEPTTFGVKMALWYTEMKRNLERFKQVRKEI-EVGKMSGAVGTFANIPPEIEAYVCEHL----GLDAAPVSTQTLQRDRHAYYV---ATLALISTSMEKFAVEIRNLQKTETREVEEAFA-KGQKGSSAMPHKRNPIGSENITGIA-RVIRGYVTTAYENVPLWHERDISHSSAERIMLPDVTIALDYGLNRFTNIVERLTVFEDNMLANIDKTFGLIYSqrvllalinkgLAREAAYDKVQPKAMESWETKTPFRTLIEEDAtitdLLTKEDLDECFNPK------------------
>UniRef50_B2S8N8(43-427:466) Argininosuccinate lyase n=428 Tax=cellular organisms RepID=ARLY_BRUA1  E=6e-40 s/c=0.44 id=23% cov=79%
---------------------------------------------------GSLAHAAMLA--KTGIIAAEDHKQIENGLKTIrkeIEEGKFT--FSRKL------EDIHMNIEARLA----ELIGPAAG---------RLHTARSRNDQVAVDFRLWVKQELEKTAAALKNLIEAFLERAEEHAATVMPGFTHLQTAQPVTFGHHCMAYVEMFGRDLSRVRDAIERIDESPLGAAALaGTGFPIDRHMTAKA---------LGFRePTRNSLDSVSDRDYALEFLSLAAICAGHLSRLAEEIVIW-STPQ--FNFVRLsDAFSTGSSIMPQKKNPDAAELVRAKTGRINGSLVALLTIMKGLPLAYSKDMQEDKEQVFDAAENLELAIAAMA-GMVRDLTVNVAAMKKAAGSGYSTATDLADWLVRTLGLPFREAHHVTGRAVALAESRKVDLAKLSLEELQS----INPAITAE--------
>UniRef50_A7X0H4(38-430:459) Argininosuccinate lyase n=69 Tax=Firmicutes RepID=ARLY_STAA1   E=1e-39 s/c=0.42 id=21% cov=79%
---------------------------------------------------GSIAHATMLANQ--GIISQQDSEQIIQGLKSIQHDYHQDQiQFSASL--------------EDIHlNIEHELIKRIGDAGGKLH------TGRSRNDQVATDMHLYTKKQVQDIIALIKSLQSVIVDIASNNVDTIMPGYTHLQRAQPISFAHHIMTYFWMLQRDQQRFEDSLKRIDINPLGAAALsGTTYPIDRH-------ETTALLNFG-SLYENSLDAVSDRDYIIETLHNISLTMVHLSRFAEEIIFWSTDEA---KFITLsDAFSTGSSIMPQKKNPDMAELIRGKVGRTTGHLMSMLMTLKGLPLAYNKDMQEDKEGLFDAVHTIKGSLRIF-EGMIQTMTINKERLNQTVKEDFSNATELADYLvtknipfrtAHEIVGKIVLECIQQGHYLLDVPLATYQQHhssiDADIYDYLQPEN-----------------
>UniRef50_Q2GFQ7(38-411:470) Argininosuccinate lyase n=6 Tax=Alphaproteobacteria RepID=ARLY_EHRCR  E=3e-38 s/c=0.43 id=23% cov=56%
------------------------------------------------------------------------------------------------------------------------------------------HTARSRNDQVATDFKLWIRKSIVKLETLLHELQQTILNIAEANYDTIMPGFTHLQIAQPVTLGHHLMAYFEMLKRDCSRWQDLHKRMNQCPAGSAALaGTSFPIDRHF-------IAQELKFD-SPTENSIDAVSDRDYVIEFLSNASICIMHLSRLAEEIILWCS---YNFKFITLSDNItTGSSIMPQKKNPDAAELIRGKTGRIFASLNQILVVMKGLPLAYSKDMQEDKEPVFDAANNLMLCIEAMNS-MLNNITINKSNMLKAAEHDYSTATDLA--------------------------------------------------------------
>UniRef50_B0S952(22-421:434) Adenylosuccinate lyase n=13 Tax=Bacteria RepID=B0S952_LEPBA   E=4e-38 s/c=0.40 id=22% cov=77%
----------------------------------------------------------ARANR--GEVPKEDLETIKQKAkfnvDEIleIESKVHHD---VIAYLT--------NLNSYI---------GPAGR--------HVHFGLTSSDVGDTALCVQMVQAMDLLIQRTETLLETTKQKAKEYKDLPCIGRSHGIHAEPMTLGLKFALFFAEMTRNLERMKDAREQVAVGKLSG-AVGTYSNIDLEIEEYVLNKL----GLKVDPIATQVISRDRHAFYMSVLGVV---AASLDRMATEIRLLQKTEGREVEEPFA-KGQKGSSAMPHKRNPVVCERISGIS-RVIRSNVNVGLQNVGLWHERDISHSSAERIVLPDSTIALDYILEKMNFVLKGLHVYPDATERTLNVTRGLIfsqkvllwLIEKGGITREDAYLIVQENamavwADQSKNLRDLLKQDprcsSILKDSDLDEIFQIKPYLE--------------
>UniRef50_C4L7S8(104-384:461) Argininosuccinate lyase n=213 Tax=cellular organisms RepID=ARLY_TOLAT  E=3e-37 s/c=0.57 id=23% cov=59%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNDQVATDLKLWCKQQGNLLLDSIHGLQTKLVATARQYQTTVLPGYTHLQRAQPVTFSHWALAYVEMLDRDYSRLQDALKRLNTSPLGSGALaGTAYAIDR-------QVLALDLGFD-RATRNSLDSVSDRDHVIELMSSAALSMIHLSRFAEDLIFYASGE-AGFIELSD-KVTSGSSLMPQKKNPDALELIRGKTGRVAGALNGMLMTLKALPLAYNKDMQEDKEGLFDALDTWHD-CLDMAQLVLEDLKVNEPVTKAAAMG------------GYSNATELADYLVAKGIPFREA-------------------------------------
>UniRef50_B1L6M1(5-436:456) Adenylosuccinate lyase n=1 Tax=Candidatus Korarchaeum cryptofilum OPF8 RepID=B1L6M1_KORCO  E=8e-37 s/c=0.36 id=20% cov=87%
-----------------PIDSRYGSELMRAI--FRQENR--------IKLMARVEALYARALAERGFIPKEAAEAIERAAEEVTPEDVRAEEALV--------------KHETMAlVRAISKRAGRYGEY--------LHLGLTSNDVLDTVMGVQIRQAGSIILRSSASLLEKIVKRGEESLDIVCLGRTHGVVADPIPLSMKFALWSYYVRRSIARFMDSLNEASVGKLRG-AVGTAAASIELGIKDPLEVESEVLAALGLSPPEITTQVVPRDRLAHLILSMSLFSSALDTIANEIRNLHRTEISEVKE-HFEERQVGSSTMPHKMNPINSEKVCGLA-RLMRSLAIAALENVVLEHERDLTNSSVERAILpEAFLILEEQINTLSA-VIENLEIDRVRIGENLEKygdialsERLMIWLVKKGLGRQEAHEIVRsislRSHRSGRRFIDEVLADeslsKILRPEEIEAIFSPRSYLGLGRE----------
>UniRef50_B0T2T7(36-433:455) Argininosuccinate lyase n=9 Tax=Bacteria RepID=ARLY_CAUSK   E=9e-37 s/c=0.39 id=22% cov=68%
------------------------------------------------------------------------------------------------------------------------------------------HTARSRNDQVAVDFRLWVREACDRSAAQLEALQKALVAQAEQYADALMPGFTHLQPAQPVTFGHHLMAYVEMFGRDASRFRDARVRMNECPLGAAAL--------AGSPFPIDRHATAASLGFdRPTANSLDSVSARDFALEALSAASICATHLSRLAEEIVLW-TTPMFGFVKLTD-AFTTGSSIMPQKKNPDAAELVRAKVGRILGSLTTLTVVMKGLPLAYSKDMQEDKVPTFEAFDALELSLLAMA-GMVSDLTPNTEKMAAAAGAGFSTATDLAdwlvrelnmPFRDAHHVTGSAVKAAETlGVDLAELSLADLRAIEPRITS--DIYTVLTPAASAASRI-----
>UniRef50_A2Q840(49-468:477) Contig An01c0080, complete genome n=14 Tax=cellular organisms RepID=A2Q840_ASPNC  E=2e-36 s/c=0.37 id=19% cov=80%
------------------------------------------------------EAALARAQSRCDVIPSQIGEMVTRKLRESkldMERLRYETEIVGYPILP-------------LVRQLSAICGDEAGKY--------VHWGATTQDIMDLASVLQMKEGLDIVEHHLKKVISTLRGLSVKYKDTPMAGRTHLQHALPVTFGYKCAVWLSGFQRHLERLEQLKDRCLLVQFGGAAgsmasLGTG-----DDGLRVRKALAEELGLTDPPITWHV----ARDGIAEITNFLALMGGSMGKLALDIIIMSSNELGEVSEPFVPHRGA-SSTMPQKRNPISSEVIL-AASKILRSNAGLVLDGMVADFER-ASGPwhLEWVAIPESFVIAVGALSQ-TQFALSGLCVHSQKMLENLHSTKGLIVAeavmmgLAPHVGRQQAHdtvyEACRESIEANQSLLECLMKKtevtSKMSEERLSQLYDPVNYLGASTR----------
>UniRef50_C9KQG3(23-413:430) Adenylosuccinate lyase n=1 Tax=Mitsuokella multacida DSM 20544 RepID=C9KQG3_9FIRM  E=8e-36 s/c=0.39 id=22% cov=78%
-----------------------------------------------------VEMAACDAMAELGEIPKEAAKNI-----------RAKAKFDVNRIHEIESVTHH----DIIAfltNVA-ENVGD---DSKYIH------KGLTSSDVKDTAYCMMMRDACTIILDDLKKFREVLRRRAKEFKHTPCIGRTHGIHAEPMTFGLKLLLWSAEIERDIERMEHAKKIVSVCKLSG-AVGTYSNIDPKIEQMVGKKL----GLTPVRLATQVIQRDRHAEFVT---SIAICSSTLEKIATEVRNLQRTDIREAEEYFSPG-QKGSSAMPHKRNPINCERISGMARLNRGNAVA-ALEDITLWHERDISHSSVERVILPDSSINLDYCTQKLTDIIDKLLVYPDKMLHDMNRTGGLIYSQRILLSvvdkgvlREDAYKWVQRnAMKrwmEGQDFRTSVENDpditKYLTKEEIDDCFD--------------------
>UniRef50_Q0AM30(59-435:472) Argininosuccinate lyase n=7 Tax=Alphaproteobacteria RepID=ARLY_MARMM  E=1e-35 s/c=0.41 id=22% cov=74%
-----------------------------------------------------------------GVISSADAAAIQRGLEQV-RSEIHAGDFPW----SKALEDVHMNVE----ARLKEIIGEPAG---------RLHTARSRNDQVATDFRLWLRDACDRIDAMLAAYQTALVKQAETHADQVMPGFTHLQTAQPVSLGHHLLSYVEVAQRDRGRFADARKRLNESPLGCAALaGTAFPIDREMT-------ASDLGFD-RPMANSLDGVAARDFALEVLSAASICAVNLSRFAEEIVLW-CTRRFGFATLSD-AWSTGSSIMPQKRNPDAAELVRAKPGRIIGSLTGLLTVVKGLPLAYSKDLQEDKAPVFQAIDDLELALLSMA-GMAGDLSFFPEALEEAAGEAYSDATDLADYVvrelgkpfrdAHHISGSIVKLAEARGVPLAELSLAE---------------------------------
>UniRef50_A4SIM6(104-384:461) Argininosuccinate lyase n=122 Tax=Bacteria RepID=ARLY_AERS4   E=5e-35 s/c=0.54 id=22% cov=59%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNDQVATDLKLWCKAQGELLLGSISALQAGLVASARANQAAVLPGYTHLQRAQPVTFAHWALAYVEMLERDYSRLQDALKRLDTSPLGCGALaGT---------AYAIDREALALDMGFGGAtRNSLDSVSDRDHVVELMHVASLSMTHLSRFAEDLIFYNTGE-AGFVELSD-AVTSGSSLMPQKKNPDALELIRGKTGRVVGAQMGMLMSLKALPLAYNKDMQEDKEGLFDALDTWHD-CLDMAALVLIDLKVNVERTKAAAQG------------GYANATELADYLVAKGIPFREA-------------------------------------
>UniRef50_A7GXA8(43-383:467) Argininosuccinate lyase n=78 Tax=Bacteria RepID=ARLY_CAMC5   E=1e-34 s/c=0.44 id=24% cov=70%
-------------------------------------------------------KAHAKMLGACGILKPEEAAAIVAGLDAVlaqIEEGKF--EFKT------ADEDIHMAVEKRLS----ELIGSELGGR--------LHTARSRNDQVALDFRLYVLRQNEQIARQIREFIATLTSLASAHLDTLMPGYTHLQHAQPVSLAYHLLAYAFMFKRDFERFISSHERNNLCPLGSAALaGT---PHPIRRELVAQELnfAGIT-------QNAMDSVSDRDFALEILFNISVLMTHASRLCEELILWSSQE---FGFVTIsDAYSTGSSIMPQKKNPDVAELIRGKTGRANGNLIALLTTMKGLPLAYNKDMQEDKEGVFDSVRTATSSLAILNA-MMKEAKFNEQNMLAATKKGHLSATDLADYLVREK-------------------------------------------------------
>UniRef50_B3E105(38-373:467) Argininosuccinate lyase n=1 Tax=Methylacidiphilum infernorum V4 RepID=B3E105_METI4  E=2e-34 s/c=0.44 id=22% cov=66%
---------------------------------------------------------------KIGIIDPKESEEIQRGLTEILEE-IEEGQFKWS-------TQledIHMNIESALINKTKAGLK--------------LHTGRSRNDQIATTMRLWVKEEVQKILSLLSRLQAVLVLWAEENIEVVIPGYTHLQKAQVVSLAHQILAYVEMLERDKEKFKECYNNTDVLVLGSGALaGSSIELDREY-------VANLLGFS-RISQNSMDGVSDRDFVLDFLYGASTLGIHLSRFAEDMVLWSS---SEWGFLELPdAFSSGSSLMPNKKNPDCFELLRGKSARLISNLNRLSILLKSLPLTYNRDMQEDKEPLFDSADTVE-SCLEMLIAMIPKLKIKKSLCLKQSEDPLLFAT-----------------------------------------------------------------
>UniRef50_A7GVW1(24-416:447) Adenylosuccinate lyase n=27 Tax=Bacteria RepID=A7GVW1_CAMC5   E=5e-34 s/c=0.37 id=22% cov=67%
-----------------------------------------------------VELAAVKAWNKLGFITDADCEKICKNAkfdvmriDEIEKTTKHD----------------------VIAFLTS--VSESLGEESRF-----VHYGMTSSDCIDTAAALQIKGSLELIIEDVQNLLSAVKSRAMEHKNTLMVGRSHGIHGEPITFGLVLAIWYDEIKRALKLITDAKEVASYGKLSG-AMGNLAHAPMEFEELTC----ELLRLRPAPASNQVIQ---RDRYAHVISAIAILAATCEKIAIAIRHYQRTEVYEAEEYFSPG-QKGSSAMPHKRNPVLSENITGLC-RMLRSYVTPALENVALWHERDISHSSVERFILPDAFVTADFMLARLANLIQNLVVYPENMMKNLNLTGGL-------------------------------------------------------------------
>UniRef50_O29379(47-425:483) Argininosuccinate lyase n=2 Tax=Archaeoglobaceae RepID=ARLY_ARCFU   E=1e-33 s/c=0.39 id=23% cov=65%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNDEVATCLRMFARDHLLNLAEAILNALDVLIKKAEK-SHFLMPGFTHLQYAQPTRLSHHLLAYHDMLSRDFERAIEAFRRVNKSPLGSAAfASTGYSLDRVYA-------ARLLGFDGVV-EHSEDAVASRDFVIESIFVAAEAMLSISRIAEEIVLFSS----EFGFITLPdEFSSTSSIMPQKKNPDIAELLRANAGKIAGNLTSAMMIYKATPFSYNRDFQEMNPLLYESLKRTHLAVEVFAS-MMGKIKFNPEITERKASKGFATATELAdmlvmkygvpfrmahRIVGRLAAKELERpTASDVNSAAKELGVEINVRDEDVLEA-LDVEKVVE--------------
>UniRef50_A6V1S9(30-438:477) Probable lyase n=7 Tax=Pseudomonas aeruginosa RepID=A6V1S9_PSEA7   E=2e-33 s/c=0.36 id=21% cov=79%
-----------------------------------------------------VERALAATQAELGLIPHEAAQEIARVARverfDLAALGRESletGHLLVPTIRALA--------------RACE---GGRGEY--------VHYGVTTQDILDTGLILQVKEAWGHALGLLHSIRGHLLALALRHRHTPMVARTHGQQALPTTFGYKVAVWVDEIDRHLARFDEARERVLVGNLTG-AVGT-LAAFGAQGFEIQRRtLARLgLGAPLTSWH------SARDRVLEAAWLLVQVSLTLGRVATEVYHLQ---RSEIDELREPARpgQVGSSTMPHKQNPSTVDLISALSRLVRSQMVALTDAAFQLH-ERDGTTWRIEWAALPELFVYAGALLTRMEALLaEGLEVREERMRANLDLLGGLIlservmLALAGQFGKQSAHELLHEvslaSARQGVPFREALLAhprlRGCFPAQTLEALLDPLGYVGLAA-----------
>UniRef50_Q4FNK3(89-402:462) Argininosuccinate lyase n=3 Tax=Candidatus Pelagibacter RepID=ARLY_PELUB  E=3e-33 s/c=0.46 id=21% cov=57%
----------------------------------------------------------------------------------------------------------------------------------------YVHTARSRNDQVITDFKMWTTSATKEINKNLDNIIKTILKISEKNIETIMPGFTHLKNAQAVSFAHYLMSYVEMFNRDKKRFTYNLESLSENPLGVAALtGTSFNIDRNFT-------SKKLGFK-RPTNNSIDTVADRDFVLDFLYSASVCSMHISRIAEELIIWNSD---GFNLITLsDKVVTGSSIMPQKKNPDLLEYLRGKTGTVYGNLFSMLTILKGLPISYFKDLQDDKEILFKSNEILNNSIAILNE-VLKNLKPNKQQMLDLANSGYITATDLADYL-----------------------------------------------------------
>UniRef50_C8WK16(84-446:461) Adenylosuccinate lyase n=12 Tax=Bacteria RepID=C8WK16_EGGLE   E=5e-33 s/c=0.40 id=22% cov=65%
-----------------------------------------------------------------------------------------------------------------------------------------VHYGMTSSDLGDTALSYQITQAIDIILEDIKQLGETCKRRAFEFQETLCVGRTHGIHAEPMTFGMKFGSWAWALKRAQTRMEEARKVAATGAISG-AVGTYSSIDPFVEQYVCERL----GLAADPLSTQVLARDRH---AQVMAGLAVTASTLESIAMQVRLLQ---QSDVIEAEEPfaKGQKGSSAMPHKRNPITAERVCGLA-RTVKSNAQVAFDNVALWYERDISHSgaervaladsfIALDYMFGKMQWMLDGLQTYPAK----MEHNLWRTKGLIFSSKVLLALVDTGISREDAYVIVQRnAMKvwediqnavDGPTYREnlEADPEANLSAEVLDEIFDPWDFL---------------
>UniRef50_A9A3T9(30-446:453) Adenylosuccinate lyase n=3 Tax=Archaea RepID=A9A3T9_NITMS   E=1e-32 s/c=0.34 id=20% cov=81%
---------------------------------------------------LQIEGAAAISQSEIGMIPKTVGRKIFKTA----NSGKITAK---RIKQLEAK------SDHDTAALVESLSEKCTKDARPW-----IHYGLTSNDLVDTSNSMQMRDALLIIEPKVAKIASILAKKAVKHSKVPAVGRTHGQHASIISFGLKFANWAAEMAKHVERIEEIKKRILICkTLG--VVGTG-SLMGAKSLEVQRRAAKRLKLFPAEVTTQVVPRERYAEYVF---ELALIGATLEKIAIEIRNLQRTEIGEVAE-QFKKGQMGSSAVPVKRNPIKSERVSSLSKLV-RSQVALSFENIPLWHERDLSNSANERFVIPTVSILVDEMLETMTRIVSNLLVNEKRIVDNLYITKGqifaefVLEALIkkgvpRFVAYRDVQRVAFLANDKGMLYKDAIKNDKAftskLTDKEIDAIFSPEKHLG--------------
>UniRef50_B7IJ66(101-434:451) Adenylosuccinate lyase n=4 Tax=Bacillus cereus group RepID=B7IJ66_BACC2  E=1e-32 s/c=0.43 id=19% cov=66%
----------------------------------------------------------------------------------------------------------------------------------------YIHWGATTQDIIDTGLTLQIKGAHELIYNQTQEILKICLRLSQQYKSTVMPGRTLGQHALPITFGYKISIWSDELGRHLERLQQGADR-YLVGQLGGAVGTlaslgaqGLAVRKEY----VKNLNLI--EPLVSWH------TSRDRFAEFSMILNMIGATTAKVAEEIISLQGTEIREVEE-GYHSGKVGSSTMPHKRNPMTCSYIVGLT-KIVNRKSTLAIDSMIQKHERDVTFWQSEWSYISEICITLSGALEQLKNVLTNLIVNEEQMKKNLFLTKGLIVSENvmlelgKIIGRTTAHdllyELTMRAFEEDKDLKDILLEdneiKKYFSDEEINSLTNPESYTG--------------
>UniRef50_D1AEI5(32-423:436) Adenylosuccinate lyase n=7 Tax=Actinomycetales RepID=D1AEI5_THECD   E=1e-32 s/c=0.36 id=20% cov=66%
----------------------------------------------------------------------------------------------------------------------------------------YVHFGMTSSDLLDTALAVQLVEATDILLEKADRLVAVLRDHALEHRNTLRVGRTHGIHGEPDVWGHRVADFAFAMARSRDRLRRAREAVGVMAISG-AVGTYSNIDPAVERYVAERL----GLKPADVSTQVVM---RDGISEWISALAIMATVCEAIALEVRH---GQRTEVRELWEPfgKGQKGSSAMPHKKNPIMSERLAGLA-RIVRAQIVPVLEGIPLWHERDISHSSTERIALPDASIALDYMLNLTIKLMSGLVVDAERMRANLESTGGLIytsTVLLELVemgmsrddeAYPLVQKAAMETWETGTPFRETlrkhAAAAGLtLDEARLDEVCRPERFVE--------------
>UniRef50_Q6MLQ8(14-409:418) PurB protein n=1 Tax=Bdellovibrio bacteriovorus RepID=Q6MLQ8_BDEBA   E=3e-32 s/c=0.36 id=18% cov=79%
--------------------------------------------------MMEVEIAVAQVQSQLGIIPKNAAKIIAQKARfnvkrisEIERETKHD----------------------VIAFVSN--LAENVGPQGKF-----IHYGMTSSDVLDTAFSLQVREAGVVLMKSIVALEKSLKTLVTKHAETLCAGRTHGMFAEPTTFGFKMAGFLAEAQRNKKRVKAALDNMMICKLSG-AVGT----YSSQAPKIESLVAKKLKLKTETIATQVIPRDRHAEML---SALALFGTGLERLAVELRHLQRSDVAEVTE-GFTKGQKGSSAMPHKKNPISAENITGLS-RLLRGYAIAGFENVALWHERDISHSSVERVVFPDAFIVADYACNRMSILLDGLDVNKKRMMDNIESSQGqifsshvLLALIQKGMIREEAYALVQRlchSLSYGEHLKD-----KLLVDDQIQKLLKPKE-IDEIFTGKKHKK----
>UniRef50_A9V8F9(58-453:500) Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9V8F9_MONBE   E=3e-32 s/c=0.36 id=23% cov=70%
-------------------------------------------------------QAYARAIAKVGLITEDERDALITGLDQVLAEW-ANNQFVLQPNDEDIHT-----ANER---RLKELAGPVAGK---------LHTGRSRNDQVATDMRLWLRDELTELIDLLKAFVASSIERAAADIDVLMPGYTHLQasaftllyhstptpcarllpiflRAQPIRWSHWVLSHAWAMQRDIERLTDLRKRVNVMPLGSGA----LAGHPFGIDR--QALAQDLGFD-AISFNSLDATSGRDFVAEFLFAATMVNIHLSKWAEDLCNYSSKE---FGFVQLsDAYSTGSSLMPQKKNPDSLELIRGKAGTTFGSCAGFLMTLKGLPSTYNKDLQEDKSAMFQSpaVVSLTRSCVQIATGVLSTLRINPEQMRAALSVD-MLATDLA--------------------------------------------------------------
>UniRef50_D1SZ88(8-434:453) Adenylosuccinate lyase n=1 Tax=Acidovorax avenae subsp. avenae ATCC 19860 RepID=D1SZ88_9BURK  E=3e-32 s/c=0.33 id=20% cov=79%
-----------------------------------------------------VEAALASAQADMGIIPRDAAREIAdKARVRHIDIGR-------------------MSAD--IRRIRHSLVPALRQLQAACSA-DHgewIHYGATTQDVIDTGVALQLKEFHAVALRDMRAVGRELARLAVEHRDTLMAGRTHGVQALPITFGHKCAVWLDELGRHHERLVQAAPRVL-VGMLAGAVGSQAAFGPNAAELEERVLRRLgLGVPPISwAP-------ARDRFAEYANLLALIGGTLSKIGNELFNMQRDECDEVEE-GFPEGKLGSSTMPHKRNPVSAENLAGLS-RPLRYSAAMMVEGMVQESERDGIAWKVEWKALPEACMIAGAMLFQARHLLAGLKVNAAAMAANLGRmhgyllSERVMLELSARVGKQTAHEWIYEASMHGITHKLGFAEAmrhheslgRLLTEDEIHDLTDPAGYLG--------------
>UniRef50_Q5LZ30(29-431:449) Adenylosuccinate lyase, putative n=1 Tax=Streptococcus thermophilus CNRZ1066 RepID=Q5LZ30_STRT1  E=2e-31 s/c=0.34 id=20% cov=78%
-----------------------------------------------------VEAALAKIEGDLGIIPKSAADKIVEKAK--------VDNFDFLSLQKESAEKRH----SLIAliHALQEEVGGKEGEF--------VHYGVTTQDIVDTGIMLQTKEAYNIILDHTKDLISTLAKLTKEHRSTLMIGRTHGIHAIPITFGFKLSIWLDELLRSQRRLKQLLENDVFVGSISGAVGS-YASFFGRGREVEKAVLKELGLAV---PN-ISWQPSRDRFSEFASVLGIFSGTLGKIGRELfTLM----KTEIDEVHEPfkKGEVGSSTMPQKRNPALIEGLASLTQPVFKDvDLMFQSLLIDGERDaihwRNewVALPEITSYL--------DAQIVNATYILSGLKVNQDKMLDNLNKQGALPYSERIMfevglkLGKQTAHEIVYQaamtALEENKDFIDLVYSDERVrlnfTKEDILSWVDPKN-----------------
>UniRef50_Q8NNY1(4-396:417) Adenylosuccinate lyase n=2 Tax=Corynebacterium glutamicum RepID=Q8NNY1_CORGL  E=2e-31 s/c=0.35 id=20% cov=66%
-------------------------------------------------------------------------------------------------------------------------------------PNGRVHYGATTQVIMDTGLVLQMTASLNALDKQIVRLGNALAARAEEHKDTVMPGRTHAQQAIPTTFGATLATFLDQIRRQRERLEEALERVRVISLFG--AGGNNAAQGEQAATVRAEMARLLDLKDPVVSWHVE----RDVLGDFGWVCSTLCGSMAKFGRNIVDLS---RTEIGEVFEPYNshRGASSMMPQKVNPISSELMIGISV-VAGALTSTLPRLQESGHERAAGEWQGEWLVIPTLANLAGAALDEAIVVAEGMRVDTDRMSSNLAFAGGLIMAeaqmiqLAPALGREKAHDLVYEAstktREEHTTLAEelpiIAVQHG------VEDLL-PKNFAQPA------------
>UniRef50_Q2PYG7(106-434:459) Argininosuccinate lyase n=1 Tax=uncultured marine bacterium Ant4E12 RepID=Q2PYG7_9BACT  E=3e-31 s/c=0.42 id=24% cov=65%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNDQVANDVRLFVKSEVDDLVSLAFELIAVIRTRAEEAHaeGIYLPGYTHMQQAQPVSLAHHLAAYCWMLLRDVDRLKDAKRRTDVSVLGAGALaGSSLPLNPAFT-------AADLGFD-QLFENSLDAVSDRDFVADVLYALTTLGIHLSKLGEELVIWAS---SEFAFITLdDAFSTGSSMMPQKKNPDIAELARGKAGRLIGNLTGFLATQKGLPLAYNKDLQEDKEPLFDSCDTARLTLLALR-GMIQTLDFNAEAM-KLAADSP-----------YAAATDLAEYLVEQGLPFRDAhalvggLVRDSLAGAKSFAELVRDhpnlgheaQKLLEPGASYQRRK-----
>UniRef50_Q1LG43(131-468:490) 3-carboxy-cis,cis-muconate cycloisomerase n=69 Tax=Bacteria RepID=Q1LG43_RALME  E=5e-31 s/c=0.41 id=19% cov=67%
----------------------------------------------------------------------------------------------------------------------------------------YVHWGATSQDIIDTALVLQLRDALREIVVDLLRAGDACATLAATHRATPMVARTWLQHALPTTFGCKAGGWLDALRRDLTRLDHVGAQVRVIQFGG-AAGTLASLGDDAPAVAARFAAELqLDVPALPWH------AHRDRLVEVATALGMLTGTLGKMARDVSLMMQTEVGEVAEPSGPGRG-GSSTMPHKRNPVGCAAVLTAATRV-PPLVATMLAGMTQEHERALGGWQAEWDTLPQIVTLAAGALRQMADVASGLEVDEARMRANLDITHGLILGeatmleLGRRIGRLQAHHLVeqasRRAAAEDTTLR-IALARtlaedanhaGLLDDAALDRLSDPAQYAG--------------
>UniRef50_Q9ZKA2(89-417:440) Adenylosuccinate lyase n=23 Tax=Bacteria RepID=PUR8_HELPJ   E=7e-31 s/c=0.42 id=23% cov=66%
----------------------------------------------------------------------------------------------------------------------------------------------TSSDCIDTAMALLMTKSLKLIQKGVKNLYETLKNRALEHQDTLMVGRSHGVFGEPITFGLVLALFADEIKRHLKALDLTMEFISVGAISG-AMGNFAHAPLELEELACGFL----GLKTANISNQVIQ---RDRYARLACDLALLASSCEKIAVNIRHLQRSEVYEVEEAF-SAGQKGSSAMPHKRNPILSENITGLC-RVIRSFTTPMLENVALWHERDMSHSSVERFALPDLFITSDFMLSRLNSVIENLVVYPKNMLKNLALSGGLvfsqrVLLELPKKGlsREESYSIVQE---NAMKIWEVLQQGAFKNADEnlfLNALLNDERL-------KKYLNESE-
>UniRef50_A6F014(23-415:447) Fumarate lyase n=1 Tax=Marinobacter algicola DG893 RepID=A6F014_9ALTE  E=2e-30 s/c=0.35 id=24% cov=65%
-----------------------------------------------IKAMLKVEGQLALAQADVGLIPQEAADAINQATQLLepdlvaLAAGVASAGVPVP---------------------ALVKALKKTLSQDFAR---WVHFGATSQDIVDTALILNCRELIKIYRQRLLEAIRLCVQLAEAHRGTLIAGRTRTQQAIPMSFGLKVANWIAPLLRQFERLEELVPRLLKVQLGG-AVGS-LAAMGDGADAVVKNLADRLSLQNAPSWH-----AQRDSLVEFSGWLAMTTGILGKMAEDwLRMAQ----TEVGELRF-SNGGGSSTMPQKCNPVNAEIMVTMARQ---------NAGLAGQMQ---------QCMLHEHErsgyawtqewlllpqMLMGTAVSLR-HCLEGlesLEISAENVETNIAKSHGLI------------------------------------------------------------------
>UniRef50_A8M7B1(50-450:471) Fumarate lyase n=1 Tax=Salinispora arenicola CNS-205 RepID=A8M7B1_SALAI  E=5e-30 s/c=0.33 id=21% cov=79%
-----------------------------------------------------IEAALAQAQGELGMIPARAVAGIVSAARLECID--------LDAVQAeidRSGHSL------VGLLRVLQVaCPDDTGEY--------IHFGATTQDIQDTGQALEMRDTLDELTREIAAILASLVELAEQHAGTVAVGRTHARAALPMSFGLKVASWIDELLRHTERLATARSRVVVAQLFGGAG--TMAGFGGGGVVLLERFAARLGLAVPTLGWHV----ARDRVVEFVTTLAMVSGTLGRVADEIRTIG---RPEFGEVTEPWRygKVGSSTMPHKRNPERCEQVV-VMAKLAAAQAGIAFTAMVGDHERDARALRVEWACVPDVSHYTLAACEIVRELVTGLTVHEDRLRvnaqevadQLATERLML--ALGRQLGkqtaHERVYELSQTAHDTGRPLRhlfdDCADLRDLVDERELDVIFDPSQYLG--------------
>UniRef50_Q7TUR9(20-346:431) Fumarate lyase:Adenylosuccinate lyase n=25 Tax=Bacteria RepID=Q7TUR9_PROMM  E=8e-30 s/c=0.41 id=23% cov=57%
-----------------------------------------------------VEIAACEANCQLGKIPAAEMQQIRERATfepqrilEIEAEVRHD----VIAFLT--------NVNEHV---------GDAGRYI------HVGM--TSSDVLDTGLALQLKNSVALLKQELGSLQEAIRSLAVEHKGTVMIGRSHAIHGEPITFGFKLAGWLAETMRNAERLERLERDV-AVGQISGAMGTYANTDPKVEQLTCERLCLI----PDTASTQVISRDRHADYVQ---TLALVGASLDRFATEIRNLQRTDVLEVEE-SFAKGQKGSSAMPHKRNPIRAERISGLA-RVLRSYVVAALENVALWHERD--------------------------------------------------------------------------------------------------------------------
>UniRef50_Q2FR16(89-412:493) Argininosuccinate lyase n=4 Tax=Methanomicrobiales RepID=ARLY_METHJ   E=1e-28 s/c=0.40 id=21% cov=53%
--------------------------------------------------------------------------------------------------------------------------------------------GRSRNDEVATCLRIRTRDIILDQLEALTRLRSVLLSVAADHITTVMPGFTHLQHAQPVTLAHHLLAYEQMFSRDFDRLFDALRRVNCSPLGSAALAsTGYPLDRPFT-------ADLLGFD-RILVNSMDAVASRDFAEETLACDTMLLTNISRFCEELIIWSS---AFVQFVNLDDRYcSTSSIMPQKKNPDVAEILRSRTGTILGSFVSAITIVKGLPMAYNRDLQDLNPHLWRGITGVRRDIDLLA-GMVESATFNRERMAE---------------------------------------------------------------------------
>UniRef50_Q0SJY5(30-468:493) Probable adenylosuccinate lyase n=1 Tax=Rhodococcus jostii RHA1 RepID=Q0SJY5_RHOSR  E=1e-28 s/c=0.30 id=21% cov=86%
-----RHEGGTMG-VGLDDDLLrdfFGNAEQRA----------IFDGPQRLQGWLDVERALAQTQAELGIIPAEAAQRISAHCQsDLFDINKLRQH-------------VNATQHPIVPMVnALEKLvGTEFGQF--------VHYGATSQDIMDSGQALQLRQSLQGIERDVAAATKAAASLALKHRNTTQVGRTHGQHAVPISFGLKAATWVDELQRLQTRIAESRDRILTVQIFGAA-----GSMAGYGDRAFEVkagVASRLGLTEPVAPWH----ATRDRIAELGSLMALLAGVSERIAAEVIRLQS---TEFGELVEP-LQPghiGSSTMPQKRNPHLSEGIVAKA-RIAQSLSAGLLRNGAHQHERDMGAWAVEWLTVPELMVGSGAMAADLNHLLEGLQVNAECMRRNVgitggqvnAESLMMI--LDSSIGRDHAHhllvELTRSADLQNLNFSEVATADervaSHLSQDQIMKALDPAQYLG--------------
>UniRef50_A9NHU6(88-412:430) Adenylosuccinate lyase n=2 Tax=Mollicutes RepID=A9NHU6_ACHLI   E=2e-28 s/c=0.40 id=17% cov=65%
------------------------------------------------------------------------------------------------------------------------------------------HYGLTSTDVVDSALALILRQANQAIRSKINKLLSVLKQKAYTYKDQPTIGRTHGIHAEITSFGLKFALWYSDLKRLLSVFDAACKNIEVIKISG-AVGNyAANTP-----QLEKTVSRLLDIASADISTQVLQRDRHANYI---SSIALLGSELEKIATEIRHLSRTEVSEVNEYF-SVDQKGSSAMPHKKNPVSSENISGLS-RVLRGYVLTAFENINLWHERDISHSSAERIILADATTLIDYMLDRITNTLSNLEVHALKLQNNIDitggivfsqhvLSLLIDKGLTRDHAYDLVQKIATDAMSNQKDFKTELLKSsdimKFMTPDELDKAFD--------------------
>UniRef50_UPI0001909CE5(1-115:121) aspartate ammonia-lyase n=1 Tax=Rhizobium etli CIAT 894 RepID=UPI0001909CE5  E=2e-28 s/c=1.12 id=36% cov=24%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TMAAEGGQLQLNAFEPVIVFNLLQSISLMTNAFYTLADKCVAGIVANEETCRHSLEAGTALATALTSLIGYEKAAELARQILSTGRTMRELLEEDSSLSASLIEQALEVKSLTQP-------------
>UniRef50_B9XS90(1-115:126) Aspartate ammonia-lyase (Aspartase) n=2 Tax=Bacteria RepID=B9XS90_9BACT  E=3e-28 s/c=1.12 id=37% cov=24%
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTMAAEAGQLQLNAFEPVMAHVLFENLKWMTAAMTTLRVNCVEGITANRERLAREVDSFVGVITALIPHIGYGPAAKMAKEALASHANIAELVVKSGVLTREQVDTMLSPERLTS--------------
>UniRef50_Q0SH25(28-429:450) 3-carboxy-cis,cis-muconate cycloisomerase n=7 Tax=Actinomycetales RepID=Q0SH25_RHOSR  E=3e-28 s/c=0.32 id=22% cov=80%
-------------------------------------------------ALVEVEGALARAEAKCDVIPAASADAISSVFARVVAEGSVDVGALGVAAAAGG--------NPVIplvKLLRSEVAAADLGVSGS-----HVHKGATSQDILDTALMLLCRRSGAHILASLDEAVVCAEALARAQRDTPIAGRTLGQQALPTTFGVLAAGWMTALHRASRALFDALDGL-PVQLGG-AAGTSAALYPH-GLDVADVLADELGLARQDVPWH----TDRTRIALLASALGTAAGAVSKIATDLVFLSSTEVGEVSE----GSPGGSSAMPHKRNPVAAIAARaaarrtpGLVATILGSmDHEQQRAAGAWHAE---------WETLTDLLRLTGGAVARIADSLGGLNVHPDAMARNLDITGGLLLAER-VTGAlsartDNARALVTAACETGHPLDEDPGLLEYLQADEIRALLDPAGYLG--------------
>UniRef50_Q2RWH5(89-419:437) Adenylosuccinate lyase n=13 Tax=Bacteria RepID=Q2RWH5_RHORT   E=3e-28 s/c=0.39 id=18% cov=65%
-----------------------------------------------------------------------------------------------------------------------------------------IHQGMTSSDVLDTCLAVQLTQAADLLLEDIDALLAALRTRAFEHKMTVCMGRSHGIHAEPVTMGLKFAGFHAEFQRARTRLVAARGEIATCAISG-AVGTFANIDPRVEEHVAAKL----GLLPEPLSTQVIPRDRHAQFFAVLG---VIASSVERAALEIRHLQRTEVREVEE-FFSKGQKGSSAMPHKRNPVLTENLTGLARMV-RAYALPAMENVALWHERDISHSSVERMIGPDATVtldfaLARLTGVFTNLVIypEAIDRTLNQMGGLVFSQRVLLALTQAGVSREEAYRIVQRNAMEvwnGQGglldrLKADAAVTDKLTPEALEELFD--------------------
>UniRef50_C4KY42(53-415:466) Argininosuccinate lyase n=17 Tax=pseudomallei group RepID=C4KY42_BURPS  E=5e-28 s/c=0.35 id=24% cov=55%
------------------------------------------------------------------------------------------------------------------------------------------HTARSRNDQQASAQRLYFMRSTRELVDAIDALQRAILEHGERHDALVMPSYTHLQRAEFTYYAHWLATYVVMLERDRSRFVDALARADQCPLGACAsTGTSLPIDRR-------RSASRLGFR-EPTLHSIDSVSDRDYLVEFCSHAANLMIHLSRLSEELISFTSQE---FGFIALADGYcTGSSIMPQKKNPDVPELVRGKAASVIGNAMSLMALLKALPLGYNKDLQEDKTAWFAALDNCMSSLAILTE-LVRTMAPVPDRMRQATLGGHIIAT-----------------------------------------------------------------
>UniRef50_Q11IU4(26-417:435) Adenylosuccinate lyase n=24 Tax=Bacteria RepID=Q11IU4_MESSB   E=5e-28 s/c=0.33 id=20% cov=77%
-----------------------------------------------------IEAHAADAMAKLGIVPQEAARTIwekggnatfdIDRIDEIERETKHD----------------------VIAFLTH--------LSEIVGPEARfVHQGMTSSDVLDTCLNVQLVRASDILLDDLDRLLEVLKKRAFEHKDTVTIGRSHGIHAEPTTFGIKLAQAYAEFSRCRERLEHAREEVATCAISG-AVGTFANIDP----RVEEHVAEKMGLKPEPVSTQVIPRDRHAMFF---ATLAVIASSIERLATEIRHLQRTEVLEAEEYFSPG-QKGSSAMPHKRNPVLSENLTGLARMV-RSYAMPAMENVALWHERDISHSSVERMIGPDATVTLDFALVRLTGLMEKLVVYPENMLRNLDRFRGLVhsqrvlLALTqAGVSREDAYRLVQRNAmkvwEHGADFQQELLADKdvraALSEAEIREKFD--------------------
>UniRef50_C9RPR5(54-340:467) Argininosuccinate lyase n=1 Tax=Fibrobacter succinogenes subsp. succinogenes S85 RepID=C9RPR5_FIBSS  E=1e-27 s/c=0.44 id=24% cov=48%
-----------------------------------------------------------------------------------------------------------------------------------------IHTGRSRNDQVCTDFKLYMRHRAAEIRQLEIELMETVLDLSKKYFGKMMPGYTHLQQAQPIYFSHYLMSMFFAVSRDVKRLDNFLELHSQLPLGSGAM-----AGSAF-PYHRALVAEALGFKDV-SPNSIDAVSHRDMMLEFNADLAIIANTMSRYAEDFVNWSS---SEFGYLTLhDAFSSGSSMMPQKKNPDSMELIRGKSGRMLGNFTALYTLAKGAPLSYSRDLQEDKEPVFDSVH-----------------------------------------------------------------------------------------------------
>UniRef50_D0MJ53(101-368:439) Argininosuccinate lyase n=1 Tax=Rhodothermus marinus DSM 4252 RepID=D0MJ53_RHOM4  E=2e-27 s/c=0.47 id=27% cov=40%
-----------------------------------------------------------------------------------------------------------------------------------------IHTGRSRNDQVLTAIRLFLKDGLREAGRRVARLVEQLCELGTAYNDALMPGYTHLQQAMPSTAGLWALGYAELLLSDLAALRHAFDQVDVSPLG-SAAGYGV----PFLELPREEVARRLG--FRALQLHVTAVQLSRGKLELHAahALVQVGATLNRIASDLVLFNSQE---FGFVELPPEcCTGSSIMPQKQNPDVPELV----------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q8TXN9(51-429:508) Argininosuccinate lyase n=1 Tax=Methanopyrus kandleri RepID=ARLY_METKA  E=4e-27 s/c=0.33 id=22% cov=64%
-------------------------------------------------------------------------------------------------------------------------------------------LGRSRNDQVATSVRMRLRERALDLSRELVGLGRALLDLAREHAEVPIAGYTHLKRAQPCTIGFWMSTYAAAVARSARGLLRV-PGMDECPLGCSAFpGSTVPVDRH-------REAALLGFR-KPARHCGEATALRGPILEFLGRLATAASELTRLAGDLIQLCSDEL-GVVE---PPDELSstSSVMPHKKNPDALELVRAELTVVAGLKGLGDAVHGKLPMFYNRDLQVLNGLLWDSVNRFELCVRVLR-KVVEGLDVDEEAARGTVLGSHAAAVDLAELV-AERAGLTFREAHKvVGRVSARLDREGVPMSPERADRVV---------------------
>UniRef50_Q2S0F5(107-388:437) Argininosuccinate lyase n=2 Tax=Rhodothermaceae RepID=Q2S0F5_SALRD   E=5e-27 s/c=0.44 id=22% cov=52%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNDQVLAALRLYLRDALAAIGGRAAALADALCELATRHPDVLMPGYTHLQRAMPSTAALWTLGYAETLAGDLDALRHARRRINVSPLG-SAAGYGVPVIDLPREAVADRLG-------------FRAVQTHATAVQLSRGKHALAVghactqvgaTCNRLASDLVLFAT---AEFDFVDLPPEHcTGSSIMPQKQNPDVLELARAYHHRLAAQMQSLATGPSNLPGGYHRDLQLTKAAVLRSVEMTSDVLTALAE-VVRGVTFNPERTRA---------------------------------------------------------------------------
>UniRef50_B8D0M6(106-447:462) Adenylosuccinate lyase n=2 Tax=cellular organisms RepID=B8D0M6_HALOH  E=6e-27 s/c=0.36 id=22% cov=64%
-----------------------------------------------------------------------------------------------------------------------------------------VHLSATSFDIVDTANSLRYKEATEKLIvPALERLLEQWLNLAEQERDTLQIGRTHGQHAEPLTFGLVMAYYASRLHERIVNLEKVVSSLC--GKMAGAVG-AYNAsslffedPEEFEKEVLKEL----GLKPAPVSTQIVPPEYMTDYVH---SLITVFGVLADFSDDMRHLQRTEIGETGEYFA-KDQVGSSTMPHKRNPInyenvksmwktfMPRMVTMYLDQLSEHQRDLTNSASG------RFIAEIASGLMMTVDRLYKVSSR--------MKINSRKMKNNFNLSKNMIIAEPLYIflaaaGHPDAHEYVRkltlKADKEGKDLVELIKADKeietylaKLDKRQKDILYNPEQYTGIARE----------
>UniRef50_A8S1Z4(37-391:517) Putative uncharacterized protein n=1 Tax=Clostridium bolteae ATCC BAA-613 RepID=A8S1Z4_9CLOT  E=1e-26 s/c=0.35 id=26% cov=54%
-------------------------------------------------------------------------------------------------------------------------------------------LARSRNDMCVTWSHMAVRDGLLQAMEQFLYLKNAIVLFAEEHKDTLYVIHTHTQHAQPGLLGHYFLGAADMLERDFKRLCRAYDAVNQSPMGAAAVTTT-----GF-PVSRERVAELAGFS-GMIENAYDAIGNSDYLTQTASALGLCALDMGRIVTDLLLWATQEMNMIhvadGYISI------SSIMPQKRNPIALEHLR-SSLSVLKgmADTVLTGFLKSPYGDISDYE-DIEDSVFGCLELFQKNVQLFRA-VISTLEVNKELLESRAYESFSVVT-----------------------------------------------------------------
>UniRef50_C6JQT1(27-436:458) Lyase n=7 Tax=Bacteria RepID=C6JQT1_FUSVA   E=1e-26 s/c=0.30 id=21% cov=82%
-----------------------------------------------YQAWLNIEAALAKAQSEFGIIPKKAAENIEKAAKIEYIDFKLMDEIYKKIGHGFV------PFIKVFIKACDEISGENESSK-------YIHYGVTTQNIQQSGQLIILKQVHEKYLLICSKILENLAELAERNKDSVMAGRTHGKHATPITYGYKVSVWISDILASVERMKEVEKRVFKIMMGG-AVG-AFNTSGETGRKVQNRVAEILGMysMEVPSRNI---TSHKEEYIM---GLALLANNCHKIAEEVYTTSIEEYGEVSEAY-EEGTVGSSTMPQKINPKLA---KGIIANSQKLYSIVPMGLYSGsrPFEADSSSYMLFDAALeEAMELITEVLLR-TEELTRTIQIFKERMYQNVlnnkglDNSEYIMMKIAERLGKDKAHsiiyELAIKSETEHKDYLQLLKENEVISevfnEEDIKNMLKPENYIG--------------
>UniRef50_B1NME2(40-423:464) Putative ArgH n=1 Tax=uncultured Acidobacteria bacterium cosmid p2H8 RepID=B1NME2_9BACT  E=2e-26 s/c=0.32 id=20% cov=79%
--------------------------------------------------------AWARALAQAGVLAADEARQIEDALTAILESGRSDPAFVDGP-------------DEDVHSFVERVLVERLGDAGR-----RLHTGRSRNEQVSLDLRLYLRRRIPLLQQAAAGVIEALAAQAASAGDALMPSFTHFRPAQPVLVAHFFLSHAAPLRRDFARLQAARDECDALPLGSGAIaGTAYAVD-------VDALARDLGFS-RIVDNSMDASSDRDFAATFLYACAMTMVHLSRLAEDL-IIFCGDEHRFFELSD-ALSTGSSMMPQKKNPDPLELVRGKTGRAIGHLVGMLTTIKGLPTGYNKDLQEDKEAVFGAEDTLAGSLAVGRS-VVAGLTLNRDR-AASAASGLLLATDVADYLvGrgvpFRRAHEIV------GALVRKLIAERREFESLSADEWRAASDHFGPDVAAR--------
>UniRef50_B5Y8W3(11-415:432) Adenylosuccinate lyase n=1 Tax=Coprothermobacter proteolyticus DSM 5265 RepID=B5Y8W3_COPPD  E=2e-26 s/c=0.30 id=21% cov=65%
------------------------------------------------------------------------------------------------------------------------------------------HRGLTSSDIMDTVFSLQIKQSLRHINALTDETIKVLTEKADQFKHNACAGRTHGVHAEPYFFGLRFLTVAVALKRSLNMLAALEQSIPG-KLSG-ALGIYTNLDPD----IESEFLRILGLSALPVSTQIVP---RDVYAPVLFYLALEASILDKLAQDMRILQ---ITEIGEaqEEFKRGQAGSSAMPHKRNPVRWERISGLS-RVLRSQVNVALENVSLWFERDISHSSTERIVyplcFDLIAFMLKETKSLVSNSVFDssrMLANMSNSKNLLYSSRAL-SLIQQKLGREAAYKRVQDLSRqvldgEAEDFIEALRSSGLLSEEELQSITDVSDL----------------
>UniRef50_Q2SR97(88-414:432) Adenylosuccinate lyase n=5 Tax=Mollicutes RepID=Q2SR97_MYCCT   E=2e-26 s/c=0.37 id=19% cov=65%
-----------------------------------------------------------------------------------------------------------------------------------------IHLGITSTDIVDTAQNYLIKQSNQIVDNELKNICDTLKELAFEHKNTLIMGRTHGMYGEPTSLGLKFALWFDEFQRHIKRFKLAKSDIQVVKISGS-MGNYANLEPIIEEYVANKL----DMNVDSLSTQVCQRDRHIFLVEV---LANIASTLEKISTEIRLLQRSDVNELAEGFL-KNQKGSSSMPHKKNPISSENVAGLS-RYIKSIVNIVLENNNLWHERDishssnerIYLPDIFNLIVYILKRMNETLTNLVIN--QSQMLNHIKQAKNIYFSQRVLTfillnyknVTREKI-YDLIQQITFKCFKDQSDFKDEVLKSSlteYVSIQQLEELFD--------------------
>UniRef50_D2RAR8(115-438:505) Argininosuccinate lyase n=1 Tax=Gardnerella vaginalis 409-05 RepID=D2RAR8_GARVA  E=3e-26 s/c=0.38 id=19% cov=55%
--------------------------------------------------------------------------------------------------------------------------------------------GRSRNDQIAALIRMFLRRHARVIASLLLSVCQALLNQSKNAKDAVMPGRTHMQHAQPILLAHQLMAHVWPLLRDVNRFIDWDLRADESPYGAGALaGNTLGLNP-------EEVAKELGFSKVCA-NSIDATASRDLVAEFSFIAAMIGVDISRLSEEIIIWNTQE---FAFVRLdDAYSTGSSIMPQKKNPDIAELARGKAGRLIGDLTGLMATLKGLPTAYARDLQEDKEAVFDQIDTLEVLLPAFA-GMVETMKFDLNRLYEQSSTGFALAT-----------------------------------------------------------------
>UniRef50_Q13PC6(31-432:445) Putative lyase n=1 Tax=Burkholderia xenovorans LB400 RepID=Q13PC6_BURXL  E=4e-26 s/c=0.30 id=22% cov=79%
--------------------------------------------------YLKIEVALAKVEAGLGVIPQDAWRDIEQKSHSFEID---WERFRIDVEAVGYPV---MPF-------VTQLAEHCGESGEYLH------WGSTTRDITDTSFVLQLREALGVLAADLDKVRRKLREMTARHRSTLMIARTHGKHALPSTFGFRCAVWYSEVERQCERLAALRAE-PFVGQFGGAIGTLAAVGPRGLEVQSALMAEL-GLGTAE----IAWFASRDRVSEVVFRIASIAQSMASIAKSLVIMTRDELAeaseGGGE------QRGtSSAMPHKHNTVVPELVIvhgkMATQQV-----AIVMESMVQDFERDwqgHFETIAVPQTFQHAHAAVTQMHTVLSGLIlheDRMRANLDVTRGQVMaESVMM--ALAPKLGRKNAhhaiSRLCNQALAEDRPLGEVLRADpqvaQYLGEHELADALDPAGYIGLA------------
>UniRef50_Q7MJB9(39-441:459) Adenylosuccinate lyase n=6 Tax=Gammaproteobacteria RepID=Q7MJB9_VIBVY  E=7e-26 s/c=0.30 id=20% cov=77%
----------------------------------------------------------AEAQAELGLIPHSAASAIKQVCDIRHLDWARLAQ----------DTQTvGM---------AIKPLVDQLSEQGNDEVKQYLHWGCTTQDLLDTSLAMRLKQTLHIVRQQLVALGDQLASMALHHKRTVMVARTNAMDALPTTWGLQVSGYLQEITRHLTRLDELYPRVTT-GLYGGAVGNlssigshGLAVRQRLFAKL--ELTEPKGLGNASLDNIVELIQF---FALIHG-------TLCRIANDTELMG---RAALGEVCEGESGGGSSTMPHKANP---RAANMIqTLSRMGWMYASGAPNLMDQQDvRAASMRVLNWSLVPEASLAVSTALERGERLVANLIVNQDKMRSNFSASRNFIMSEAvmmkaaekvgRSMGYSCVKMAIAQAPEQGdlaQILKQNPEVSAILTDQEIDAACDPQHYLG--------------
>UniRef50_D0LZ81(86-381:443) Adenylosuccinate lyase n=6 Tax=Bacteria RepID=D0LZ81_HALO1   E=8e-26 s/c=0.41 id=18% cov=55%
------------------------------------------------------------------------------------------------------------------------------------------HFGMTSSDVLDTALALTCRRALERVEAGIDGLRQALARRAREHAHTPVIGRSHGIHAEPITAGLVFARWHAELGRAQARVERARAAIS-VGKIAGAVGVYGNIEPG----IEAAALGALGLAPETVATQVVARDRHAELLC---ALALLGTAIEQIAVGVRHWQRTEL-GEAEEGFGAGQKGSSAMPHKKNPILSENLTGLA-RLLRAYAGAAFENVALWHERDISHSSVERVSLPDATILADFMLARCQRVIDNLVVHPERMRENLERT----------------------------------------------------------------------
>UniRef50_B1L394(93-391:455) Argininosuccinate lyase n=1 Tax=Candidatus Korarchaeum cryptofilum OPF8 RepID=B1L394_KORCO  E=1e-25 s/c=0.40 id=30% cov=42%
--------------------------------------------------------------------------------------------------------------------------------------------GKSRNDQVATALRYVTIRELISLLWEINRLRDSLIDAALMNLEKRIPAFTHLQPAQPSTVSHYLLSIEYELFHHYRSIWHVMREIVDLcPLGsGPAAGSSVPMDRG-------RLADLLGFSGVES-NTLLATGSRSFETIVLGILSSLMVVLSRVCEDLIIW-STPNFGLVELPDDHVST-SSIMPQKRNPVTLEVIRAKAGEVMGCHFTV--------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q67KR2(139-443:538) Argininosuccinate lyase n=3 Tax=cellular organisms RepID=Q67KR2_SYMTH  E=2e-25 s/c=0.39 id=24% cov=56%
--------------------------------------------------------------------------------------------------------------------------------------------ARSRNDMGVTMYRMVLRKHLLDAIEAAQLLHRVLLRFAAEEADTVMLAHTHTQQAQPTTLGHWLTAAADVLERDIARMQAAYERANRSPMGAAALST-----SGF-PISRERVAELLGFD-GLVENSYDAIAGADYVSEAAAAVQLTALHTGRMVQDLLLWCTQEYGAL-RVADPYVQT-SSIMPQKRNPVSLEHARTLLSYTAGRAQTVLQMLHNTPFgDIVDTEDEMQPNLWAALSTLRSVFRLLA-NVVGTAEVNRDLLLERARASFANVTELA--------------------------------------------------------------
>UniRef50_Q8U705(51-447:504) Argininosuccinate lyase 2 n=4 Tax=Alphaproteobacteria RepID=ARLY2_AGRT5  E=2e-25 s/c=0.30 id=22% cov=75%
--------------------------------------------------------------RETGILDAETAAKIAGALEdidrtiepsELVYTGEVEDFFFLIE-------------KELKARIGVDVAGR-------------LHTARSRNDIDHTLFKIGLKDKIDTLTAKARVLLKALIDAAERNQSTLIVAYTHGQPAQPTTFGHYLSAAIEVLIRDIERFTEARHIVDLSPMGAAAITTsGFPIDR-------ARVAELLGFA-APLRNSYSCIAAVDYTTATYGAIELMFLHLGRLIQDFQFWTS---FEVGQIYVPNslVQI-SSIMPQKRNPVPIEHLRHLASQTFGRARTMLDVMHNTPFtDMNDSEgetQSMGYEAFAS----AGRVLDLLASLVGQISIDPERVDQNIRRSCITITELADSlvriedLSFRQAHEIAATVAKSVVALKGDLPNDGYqpflgafsgltgretgIDEEKFRQIVSPEHFV---------------
>UniRef50_Q9UX32(13-420:444) Argininosuccinate lyase n=9 Tax=Sulfolobus RepID=ARLY_SULSO   E=3e-25 s/c=0.29 id=23% cov=67%
-------------------------------------------------------------------------------------------------------------------------------------------LGRSRNDHVATALRLRLRNKLIELLTDINSLRKILLDKAKEHITTIFPSYTHLQLAQPTTFAHYLTYIEEELASRWEIIFSTLKQVNKSPLGSGAiVGTNVKIDREKE-------AELLGFD-SIIYNTLSATSSRADILSTISELTVLMVVLSRIAEDLIFFSSNKL-----IKLPDSHVStSSLMPQKRNPVTMEILRAKAAESIGMLTSLLSIYKGLPTgynldlqEMNKYYWLVINYTKSSIGVLS---SLFSQIQVNKINIDESSLATD-DAELLSISKKVPYRStyFEIAKKVREGSYKSTLKIEDSINMKAVIGSPNFDLMANLIKI----RETKLKEDEKE-
>UniRef50_B1HXH3(95-450:504) Argininosuccinate lyase 2 n=1 Tax=Lysinibacillus sphaericus C3-41 RepID=B1HXH3_LYSSC  E=3e-25 s/c=0.33 id=21% cov=69%
-----------------------------------------------------------------------------------------------------------------IENKLIELAGDVAG-------NLHI--GRSRNDMGIAIYRMTLRQKLLLLMRELLTLRDDLIAAAEEHVDTIMIGYTHTQQAQPTTFAHYLKAVIDQLERDFERMQHVYKTVNRSSMGAAALtTTGFNINR-------ERMRDLLAFD-DIIENAWDAVAGADYIAEAASIVQLAALNLGRTSQDFLLWATQEFNAFT-LASPYVQI-SSIMPQKRNPVSIEHTRSLLSAVVGDASTVLQMVHNTPFgDIVDTEDDMQPYLWRAIDRLV-GIYKLFGSLVVTMDVNKKKLRNRAENSFANVTELADTlvrsedISFRQAHSIVSKCIKvllahseeslasltwglVNTQSKLITGKELNISEEDFYKTLQPESFVG--------------
>UniRef50_Q8U483(47-381:459) Argininosuccinate lyase n=1 Tax=Pyrococcus furiosus RepID=ARLY_PYRFU  E=3e-25 s/c=0.36 id=26% cov=57%
-------------------------------------------------------------------------------------------------------------------------------------------LGRSRNDHVVCALRLKAKKALVEEIGLILELRKALIKKAEENVYTLMPLFTHLQPAQPSTFAHYLSAIIEELEDITKILFSGLGIVDKSSLGAGAIgGTSVLLDRGYMGGIL--FSDI-------ITNSLYATSSR-TFLLYSCFLSVLiSIALSRIAEDFVIF-STPN--FGYIKLPNEHLStSSMMPQKKNPVTMEVARAWAGEAIGHLVAMMSILKALPSGYNLDMQEVnkhAFALFsgtiKTLKIFVDAMKR--------VEVNKENMKKDCDIFPILATDYAEKI-----------AMNTGRPYREVYME----------------------------------
>UniRef50_Q5U9J2(102-443:451) Fumarate lyase n=2 Tax=Nocardioides sp. JS614 RepID=Q5U9J2_NOCSJ   E=3e-25 s/c=0.35 id=21% cov=59%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RRLAETYADTVMCGRTHGQPGLPITFGFKAAVWASEVARHRERVAQGAAR-WGVAQLGGALGT----MEFWGEQALPLLdsfASRLGLK---APD-IAWLTSRDRIAEFVGLLGMVTATLGKIGQEVYQLQ---RPELGEVRegLHRGVVGSITMPHKVNPEISEHLVTLA-RIVRSKVGPALEAMLHEHERDGRAWKAEWIFLPEACILTGATLSMSCQLLEELEIDEDRMMANLEDRGGYLMSepvmreLSPLLGKHVAHElvhsIAIRGREQGVGFEEVLLAErtldGLLSADEIRKALDPVAAVGSA------------
>UniRef50_B5WSC5(49-442:507) Argininosuccinate lyase n=1 Tax=Burkholderia sp. H160 RepID=B5WSC5_9BURK  E=4e-25 s/c=0.30 id=25% cov=64%
------------------------------------------------------------------------------------------------------------------------------------------HTARSRNDLQSTLDRMRARQVALSLIDGNLSLRRSLIRQATRYTDCVMPGYTHLQHAQPITYGFYLSAVERGLQRDFDRLLGAFHRLNECPLGAGAmAGTTFPVDRH-------AVSALLGFS-APVAHALDAVASKDPLLELLCAALFVATTFGRLAQDFYLMST---FEFSTLTLPDSLAiTSSIMPQKKNQAVLEFLKGRQSHLLGALVTgfASFRAAPYSHALD--------SNADSLHWLWQAVDELVetipvmDQVISRATPNSQRMAKLAGANFSTATDLADLLVQKKGLSFKEAHHITGRVVR-LAIDAGLgvadippelvsraaqeatgrdisLSREEIADALDPRA-----------------
>UniRef50_B3E0C7(87-419:441) Adenylosuccinate lyase n=1 Tax=Methylacidiphilum infernorum V4 RepID=B3E0C7_METI4  E=5e-25 s/c=0.35 id=18% cov=66%
----------------------------------------------------------------------------------------------------------------------------------------YLHFGLTSSDILDTTFALQLKEASELLLADIEKLIQRVEQKAVQYAFCPMMGRTHGVFAEPTTYGLKLLQMREEFKRAYGRLLAAQEEIIH-GMISGAVGTYAHLDPRVEKIVLDKL----GLKAEAVSSQVIPRDRHAFFLNC---IALVGCSIERWATEFRHLQ---RSEVLEVEEPfkAGQKGSSAMPHKKNPILCERLCGLA-RLLRGYALSAMENVALWHERDISHSSVERVAFPDATLLLDYMLFLLTGIVENQKVYPNRMMDNILASrqlyasegIMLALVkkgMSRKEAYEAVQQAAMNCWEKGKPLSVYAqshpLISRLLSPKEIEALCSLESYLS--------------
>UniRef50_Q02CF9(101-427:427) 3-carboxy-cis,cis-muconate cycloisomerase n=1 Tax=Candidatus Solibacter usitatus Ellin6076 RepID=Q02CF9_SOLUE  E=6e-25 s/c=0.36 id=21% cov=66%
-----------------------------------------------------------------------------------------------------------------------------------------VHWGATSQDVADTALVLLLRQAVPILQADHERTMAALHGLSERNAGAVMLGRTLLQPASPVTFGLKAAGWYAALRRGWDRVSSRFDEALCLQFGG-ASGT-LASLDDRGMSVGEALASELALREPDAPWH----GYRDRLAALMAALTIYTATLGKIALDVALLM---QFEVGEAFEPggEGRGGSSSMPQKRNPTACMLTLAAAKRVPGllADFVVGMVVEHeralGGWQ--AEWPLV-YGIVQSAAI---ALESMAEVC-DGLNVDVAKMRANVESTKGAIFAeravllLTPELGREVA----------RRQVEDAIRETG--SPPDLPGLRDPEQYLGSAEAFRKRQMQGDK
>UniRef50_A8ACF4(94-401:452) Argininosuccinate lyase n=1 Tax=Ignicoccus hospitalis KIN4/I RepID=A8ACF4_IGNH4  E=7e-25 s/c=0.38 id=24% cov=53%
-----------------------------------------------------------------------------------------------------------------------------------------INLGKSRNDQVATAIRLRVREELLESATALYHLLKALYAKAKLHEEVFFPTFTHLQPAQPANFGLFLTNFAEEIVDSFGLLEVALEITDKCPLGaAAAAGSTVDLDRR---RRCEELC------FKdLAYNTLYATTSRD-FALVSlGALASLSIPLLRFVEDVFVYATPP---FSLIRVPLDHAGtSSIMPHKKNPATLEVVRAELSKLLGHYVsafSILKGLTSGyNLDLQQLTPL----LWQAFKTFRKSVIVITDF-LWKMEVNEERAKEFL-------------------------------------------------------------------------
>UniRef50_D1A3W6(25-380:383) 3-carboxy-cis,cis-muconate cycloisomerase n=1 Tax=Thermomonospora curvata DSM 43183 RepID=D1A3W6_THECD  E=2e-24 s/c=0.33 id=25% cov=57%
------------------------------------------------RALLDAEIALARAQARLGLIPADAPAAVARAAGRITDAGRLAVQ------ARRSG-------NPVVP-IAAELRAATP----------HAHHGATSQDIADTAAMLVASRTRALILRDLDRTCAALAGLAERHRDTPMAGRTLGRPALPVTFGLKAAGWLLGCLQARRRLAQVR---LPVQLGGAA-----GTMSGYGERAVELLplyAAETGLdEPVLPWHTV-----RTPVVELGAALAQTAGALGKFATDVMLLSQEEVGEVAEPAAPGRG-GSSAMPHKRNPVLSTLIRSAALQVPA-QVAVLLTAQGG-------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q12CF4(21-388:419) 3-carboxy-cis,cis-muconate cycloisomerase n=3 Tax=Comamonadaceae RepID=Q12CF4_POLSJ  E=4e-24 s/c=0.31 id=22% cov=58%
----------------------------------------------FLDAMLRFEGSLARAQASVGLIPEAVAQSISGTC-----KVELFDVAKIVRESGRAGS---------IAIPLVKSLKETVGLFNK-DAAGFVHFGSTSQDVIDTALALVTRNALNLIEADVHKAVAALLVLAGRHAADPVLARTLMQPASVTSFGLKCAGWAAPLVRSLQRLQATAGNALSVQLGG-AVGTLAQmqkAGKNLGPQVIAHMASELKLR---APSCAWHTQ-RDEWVALGCELGLLVGSLGKIAKDIALMGQYEVGEVAEPTEPGRG-GSSAMPHKRNPVAC-MVALAAAQ----------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A8M4P0(38-462:488) Fumarate lyase n=2 Tax=Actinomycetales RepID=A8M4P0_SALAI   E=9e-24 s/c=0.27 id=21% cov=81%
-------------------------------------------------AMVEFEAALATAQARLGAVPDGTAAAIRAAGEsgrldlvELARLGREAANPVVGFVKHLTG---------LVASTAPEAAG-------------HVHAGSTSQDVLDSAAMLVATRALCLVRDDLARIRTALTELARDHRGTAAVARTLTQHAVPTTFGTKAATWLTLICDAHERVNALLRQGLPVSMGG-AAGTLAAYHDHLTAAGVAddhpelRLATLVADELGLARPTLPWHAARTPIADLAAVLNFVGGALGKFAADVLVLSRTEIAEVAE---PaAVGRGqSSAMPQKRNPVLSVLVATAARQipvyalVLGQSMVAEDERSSGAWHA-EWQP------LRECLRLAAGASHTAAELAQGVVVATERIRVNLSLTGSslvaerLSVALGQELGRQRAKEAVTRAVRDtemGVPaadaLRHALNEAGLVDGrsaclDSLDELLDPEGYLGAAAP----------
>UniRef50_A0M369(102-351:429) Argininosuccinate lyase n=10 Tax=Bacteroidetes RepID=A0M369_GRAFK   E=1e-23 s/c=0.46 id=27% cov=42%
-----------------------------------------------------------------------------------------------------------------------------------------IHTARSRNDQVLVAQQLYFKENLQQISEKAKELIEVLLGLADEHKEKLLPGYTHLQVAMPSSFGLWFSAYAELLIDDLYLLEAGLKIVDQNPLGSAAgYGSSFPIDREFT-------TRELGFSTQKFNVVAAQMSRGKCERTVTSNIASLANTLSRLAMDICLYMSQ---NFDFITFPdELTTGSSIMPHKKNPDVFELVRGKCnkLQAIAN------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6X1U1(108-378:504) Argininosuccinate lyase n=2 Tax=Ochrobactrum RepID=A6X1U1_OCHA4   E=2e-23 s/c=0.42 id=22% cov=55%
------------------------------------------------------------------------------------------------------------------------------------------HTARSRNDIDHTLFKLGLKARIDTLMTQARNLLDAMIAAAEREKETLIVAYTHGQPAQPSTFGHYLSAAVEVLIRDMERMEATRAIVNLSPMGAAAITTsGFPIDR-------ARVASLLGFA-APLPNSYSCIAAVDYITSTYSALELMFVHLGRLIQDFQFWTS---FEVGQIYVPNafVQI-SSIMPQKRNPVPIEHMRHLASQTMGRARTVLDVMHNTPFtDMNDSEgetQAMGYEAFASAGRVLDLLAAF----IGAIRIDPARVAENIRRSCITITELA--------------------------------------------------------------
>UniRef50_B2SEM1(89-421:432) Adenylosuccinate lyase n=19 Tax=Francisella RepID=B2SEM1_FRATM   E=4e-23 s/c=0.34 id=18% cov=67%
------------------------------------------------------------------------------------------------------------------------------------------HFGVTSSDIIDSALSLQIRDSMSYVIKDLEALCDSLLTKAEETKEIITMGRSHGMFAEPMSFGQKFLGAYVEFKRRLKDLKDFQKDGLTVQFSG-AVG----------NYCIlttedeKKAADILGLPVEEVSTQVIPRDRIAKLISIHGL---IASAIERLAVEIRHLHRSDVLEVYE-GFSKGQKGSSTMPHKKNPISTENLTGMA-RMLRSHVSIALENCVLWHERDISHSSAERFYLpDNFGIMVYALRRM-KNTIDNLVVQRDIIEDRVRSTSAYLSSFylhflvanTPFM-REDCYKIVQQVAFDLKQGESFSKKLQKVMHDEHNIILDILEMDFEGIK-KTYLKE---
>UniRef50_A6KYN9(104-391:446) Argininosuccinate lyase n=20 Tax=Bacteroidetes RepID=ARLY_BACV8   E=5e-23 s/c=0.39 id=26% cov=40%
-----------------------------------------------------------------------------------------------------------------------------------------IHSGRSRNDQVLVDLKLFTRAELKEVAEEVEQLFHVLISQSNTYKDVLMPGYTHLQIAMPSSFGLWFGAYAESLVDDMMFLQAAFKMCNRNPLGSAA---GYGSSFPLDREMTTRL-----LGFDSMDyNVVYAQMGRGKMErNVAFALASIAGTVSKMAFDACMFSSQ---NFGFVKLPdECTTGSSIMPHKKNPDVFELTRAKC------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q5LI10(104-361:447) Argininosuccinate lyase n=37 Tax=Bacteroidetes RepID=ARLY_BACFN   E=5e-23 s/c=0.43 id=28% cov=41%
-----------------------------------------------------------------------------------------------------------------------------------------IHSGRSRNDQVLLDLKLFTRTQIREVAEAVEQLFHVLIRQSERYKNVLMPGYTHLQIAMPSSFGLWFGAYAESLVDDMLFLQAAFKMCNKNPLG-SAAGYGSSFPLNRTMT-----TELLGFD-SLNYNVVYAQMGRGKMErNVAFALATLAGTISKLAFDACIFNSQ---NFGFVKLPdECTTGSSIMPHKKNPDVFELTRAKC------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q5WG84(36-450:457) Adenylosuccinate lyase n=4 Tax=Bacteria RepID=Q5WG84_BACSK   E=2e-22 s/c=0.26 id=19% cov=82%
--------------------------------------------------------ALAEAQAEYGLIPKKAAQEIKEAAKLENLDLEEMDRIYKEIGHG------------FVPFLKVLVKACPPDSGKYVHYGiTTQNIQQSS--------QLYILKKAHMIFMRLIgEILENLSILASDNKHTVMPGRTHGRHAIPITYGYKVSAWISELISCHQRMAEAEKRVFQVMMGG-AVGT-FSSMPEIGINVQNRVAALVGMYPMTVPSRNINTHK----LEYMSNLALLANCCHKIAEEVYSTTLEEIAEVSE-GFSKGTVGSSTMPHKINPKLAKGII-ANAQKLYSLPSIGMYSAARPYEGDSSSYMLFEGLLeESMELMTE-ILIRCEELTRTLTVHKERMLHNAKRNKGLdnseyvMMKLAEKLGKDQAHslmyEIAMKTAAEGQEFYDNLRENKQVranfTDKEIKHMIEPGNYTGLAAhlaekEAERAKETAEK
>UniRef50_A0P1F3(33-423:437) 3-carboxy-cis,cis-muconate cycloisomerase n=2 Tax=Labrenzia RepID=A0P1F3_9RHOB  E=3e-22 s/c=0.28 id=20% cov=79%
--------------------------------------------------MIAFERALATVQGRLEIIPAQAAREISEKLAGVhieparLEAGTRSAGVPVPAL---------------VAELRKQL---------SADAGAWLHWGATSQDVIDTAMVLQAKVALEILGARLEKLIDTLERQSARHADQLMAGRTRSQVATPITLGYRIAQWAHPLIDAENALPALRSAVLRVQFGG---ASGINsAIAPDGTTVSTALALELGLEDSPSWHV-----NRTPILALAGWLQQLTSALAKMAGDLAL--SG-RTDIAELA-SGTGGGSSTMPQKANPVQAETI-QVLNSIAIAAQAGLAAAASPLEERDGTAWPLEWHFLPQMLLAAGAALVHAEDLATSLQAHEANLAatlaanpEIMAETASFVLARN-GVSRAEAKDLVAAAAKDPAPFAEALARLAPVSL-DWQKELDPHQVVAPA------------
>UniRef50_A6G9Y4(101-370:441) Argininosuccinate lyase n=1 Tax=Plesiocystis pacifica SIR-1 RepID=A6G9Y4_9DELT  E=6e-22 s/c=0.40 id=23% cov=55%
---------------------------------------------------------------------------------------------------------------------------------------DKLHTGRSRNDQVATDLKLWVRSAVNRLLAGLEGLEAAIEAWNEAQGDTPMPAYTHRQVAIPV-LARLWigAALGEPLARDRRLLAVVEDEIADSPLGAGAIG--GNTLPIDPWVPARELRFSS-----PPRNPMDAVGSRDHGLTLAFACARISQHLARFCADVVELSSD---GLVTLS-GAVACGSSMMPHKRNPDLFELVRGQAALRQGELVALMTTFQGLgtgyHRDLQQDKQVLFACVDGTV-----ACLEMIALGIRNLELMPERCVTALERGDAIATDLT--------------------------------------------------------------
>UniRef50_Q1R0U7(14-433:444) 3-carboxy-cis,cis-muconate cycloisomerase n=1 Tax=Chromohalobacter salexigens DSM 3043 RepID=Q1R0U7_CHRSD  E=6e-22 s/c=0.26 id=20% cov=82%
------------------------------------TGREKCSAQDLVVAMLDVELALAAEQERLDMLPKGTTETLgEYLTTEVFDIEALAD----DTAKGG--------------NAAIPFVKQAKAALpDTLKPYFH--RGATSQDIVDSALMLLLKPRLARCRRLLTASIDDGRSLMVAHRDTTMIGRTLMQQALPITFGAKVGQWAWGLHQAGERLDDVLTGGLYVQFGG-AVGvhSGLD---DAGVAIMTGMASRLGlaepwLPWHTDRQPIHSLGCAIDAVAVAAEKVALDVALLT------------QTEIGELAEPA-EAGvgeSSSMPHKRNPVGCARIRAAARQIHAALSVLTNAGAQ-PLERGLGEWHAEWApMLDAALLLEGALETL-QHLLSGLEVNDQVMARNLGVTGGAIMAepaarvLQSILSNDEARRVAREASENarraGVDYAEALLAHedvagSAIDADALRQAVRPESYIGSSR-----------
>UniRef50_Q11KV9(107-438:502) Argininosuccinate lyase n=1 Tax=Chelativorans sp. BNC1 RepID=Q11KV9_MESSB  E=7e-22 s/c=0.32 id=26% cov=62%
--------------------------------------------------------------------------------------------------------------------------------------------GRSRNDLANAGKRMFLRDQLLRTIEAVIGYREAVVHKAADHLDTVMVVYTQRKEAQPITLGHYLMAISENLAKNLDRYRELYARINLCPLGAAAtAGTGwpLNRDRtsallGFDGLVVNSIEGVAGWDHVAEHAFVNA-------VFLSG--------LSRLASEIQLWSTDEYQ-VAE--LDASFAGtSSIMPQKKNPDSLERSRKAAFAAMGPLVGILTSLNAIEYQYSAarveLEPRSIDALIAATHAMTGVVRTL--------HPNKERMRQYAAENYSTMTDLTDMlvrrvgIDYREAHEIVAHvvitAIEKGIKankigldlVQEAAVAQTgagiNVSADDIKDALDPWQ-----------------
>UniRef50_UPI0001AF22AB(105-465:482) 3-carboxymuconate cycloisomerase PcaB n=1 Tax=Streptomyces roseosporus NRRL 11379 RepID=UPI0001AF22AB  E=1e-21 s/c=0.30 id=19% cov=67%
---------------------------------------------------------------------------------------------------------------------------------------EYVHRGSTSQDVFDTGAMLVSARVARLLLADLRRTADALYDLAAAHRDTPMAGRTLALHAVPTTFGLKAAGWRDLVLDAADRVAGVLEGGLPVSLGGAAgtlagyleyaaiaaagdapagpdRGTSAGLDRgGYLDALNGAFAAETGLARQRTPWH----SLRTPVADLAAALAFTTGALGKIAVDVQSMV---RTEVDEVAEPAV-AGrgrSSAMPHKRNPVLATLIRSAALQV----PALAAGLTQCMLAEDERSPGVWHAewpLLRGCLRLAGGAAHTAVELAEGLVVRPDRMRDNLrvtgsqMASERVAAALASGLGRGRAQELLAEASAtarhTGRPLAEVLAALpgvaACLDPRVLSVLLDPLGYTG--------------
>UniRef50_Q1L4A5(101-371:500) Iminodisuccinate carbon-nitrogen lyase n=1 Tax=Agrobacterium tumefaciens RepID=Q1L4A5_RHIRD  E=2e-21 s/c=0.39 id=27% cov=54%
------------------------------------------------------------------------------------------------------------------------------------------HTARSRNDLYATVMRIKVRGYSVQMSHLLLDLVEAVIAKASAEMKTVMTGYTHGQPGQPITAGHYLSGISEALLRDAARILEGYDRINLNPLGACALATT--TFPIDR----NRTGELLGFD-GLIENSLDAVGSRDYVPELIFGFAMAATTVSRFCADLHIWY---MAEFNYIGIDDSIAGtSSIMPQKKNPSPIEHLKAKASHLYGALMT-SLAAQRGAFfthgrevgteSTSGFGEAVKQ--FEAVAELAGAV-------VNGLVFNRERLIEAVDSNFSTMTELA--------------------------------------------------------------
>UniRef50_C9SS79(112-449:502) Argininosuccinate lyase n=1 Tax=Verticillium albo-atrum VaMs.102 RepID=C9SS79_VERA1  E=3e-21 s/c=0.31 id=20% cov=64%
----------------------------------------------------------------------------------------------------------------------------------------DIQRGRSRIDQKATNWRLINRASLTDVIRELVDLATEILATADRHTGVLMPGYTHMQHSQPTTMDHYLNAHYWAVSRSLDRLYDAYDRLNVCPLGGAAYsGTSwpINRDST---------STYLGFD-RPILNARDAgFAAIDMGAELAGVLAGTLSTISRLASDLNYWSS---SEVNLVRIDAALCGtSSMMPQKRNPMVLERIRGLAG------VAVGWAASH----LGVMhtatstdvDQSYVHNLLPGQCIETVGAIALLREVLATAEFDVPAMRISAGQHWSTASALADRLvslrglsfrdAHESVARLVEAHERAGC--RDGELRGKLiddafrhvLSESDVRSILDPVSFVESRIS----------
>UniRef50_C7MPV5(33-459:462) 3-carboxy-cis,cis-muconate cycloisomerase n=2 Tax=Actinomycetales RepID=C7MPV5_SACVD  E=4e-21 s/c=0.25 id=21% cov=81%
------------------------------------------------RAMLDFEAALAAAQADAGLIDRLHAERIERACHhnghddyDIAELGRAAR---------GAGNPA--------APLVRAITERVEGAAAR-----YVHWGATSQDVVDTAAMLVAARARMALLADVEACTETLAELADEHAATVQVARTLSQHALPTTFGLVAAGWLTSLDTAAERLQAVR---LPVQFGG-AVGTLASLGESGVEVLAALAARLGLAEPALPWH-----TDRTPVAELAGALGGLAGAVSGVARSIVTLT---QTDVGELREqgPPGSGGSSTMPHKRNPVAAVSALACAKQAPGlvADLLAAMehenqrASGAWHAE---WWPLI-----QLWRVCGSAVHWLRTS-LDRLRVDAERMRQNLDRGGGvllaerITTELAPVVGRLAAHDAVtsccHRALDEGVPLADVLVDDPLvgahLSRERIERLLDPADYLGAApvfvrRALEKYRRRKEE
>UniRef50_C9Z894(28-475:484) Putative 3-carboxy-cis,cis-muconate cycloisomerase n=1 Tax=Streptomyces scabiei 87.22 RepID=C9Z894_STRSW  E=2e-20 s/c=0.23 id=20% cov=81%
---------------------------------------------AYLRALLDAEAALTRAQAALGLVPAAAGPAVTSAADAAAFDAR-----SLAERARGGG-------NPVIPLVAdlTEAVGDPYGPY--------VHRGATSQDIMDTATMLVAARTLDLILADLGRTESALAALAAAHRDTVMPGRTLTQHAVPTTFGLKAAGWRSLVLDARDRLAVVRASL-PAQLGG-AAGT-LAAFTVFRstdESTDESTDESTDESTddgnaagSGTENAAAGTGAENA-STTHALVAAYAREVglrepelpwhtlrtpvadlagalafaagalGKVAADVLVLARTEIAEVAE----GSGGGSSAMPHKANPVRS-TLIAAAARRAPQLAAALYGALAAEDERPAgawhaeWEPL--RDLLR----LAGGAARDAVDLARGLRVDADVMRAHLDLTHGlivserLAAELAPVLGRARAKELltraARRVHAEGRPLGELLSEEPELSglGLDLADLVDPRRYTGSAA-----------
>UniRef50_A8F694(94-425:479) Fumarate lyase n=1 Tax=Thermotoga lettingae TMO RepID=A8F694_THELT   E=2e-20 s/c=0.31 id=25% cov=63%
------------------------------------------------------------------------------------------------------------------------------------------HTARSRNDIDATIFRMALRNVLIQFEKELLNLIKQFIRKAGQNIDTVFLLYTHGQPAQPSSFAHYLLAFSGELTQVSKKLIETFDIVNECPMGAGAItTTGFSIDRNL-------VSNYLGFN-RPLENSYQAI-STSHWITLPGAlLRNLMIDITRFIQDIMHKSS---SEVGVLQFPNelVQI-SSIMPQKRNPVVLEHL-----RLRANMAANAFSNIE-----NVFLNVpyqdvnengdfVLREFLNAMDI-SNQVLILLSEMVEKVIVRTDRVREIAAQfgatSTELADELVRRFGisFRKAHLIVSEVVKTGLNfenfsnvIKEHLKEKPEMeiNPEEFQHILSCEHFIE--------------
>UniRef50_Q7W582(33-444:497) Putative argininosuccinate lyase n=2 Tax=Bordetella RepID=Q7W582_BORPA  E=3e-20 s/c=0.25 id=21% cov=80%
---------------------------------------------DLFHAMSRVNLAHAVMLRDRNLIPPEAARALVALMAELFERGPSS-----VALEAGAG-----DLYPQIEAHAAALLGADVAGYLQL--------GRSRGDVIPSAMRLKLRIKLMRLLASVLALREAILDRAVERADTIMPAYTHWQQSQIMTVGHFLGRFSAWLERDTQRLFECVSR-HNLSVLGSAngVGTSVRVDRAMT-------AAWLGHD-EPTLSTGDGTNAWDYMIEPVSVAALLCSHLARLTGNFILWHTQE---FGMVRLsDAFCTASTYLPHKRNPEPLETVKVFAEQVQGALATVYLMA------RNEDWPhSLINHGFDAINgalTLSGDAADLTGAIMRDISFDPARMRELLDLSYATASEVAntlvaagglPFReAHEIVGTAVRACMADGRAaltparVRDAARGMGIdlppIDDAQLAACIDPGNFVQ--------------
>UniRef50_A1QZL0(114-440:467) Adenylosuccinate lyase n=10 Tax=cellular organisms RepID=A1QZL0_BORT9  E=4e-20 s/c=0.31 id=20% cov=63%
---------------------------------------------------------------------------------------------------------------------------------------------------------VQIKEALLLIENKLLKLINTLKKFSIKHKNLVTLAYTHLQEAQLTTLGKRSSLWLQSLIFDFEELKFIMSNMRFRGVKGT-----VGNQSSFKELFASNFEKVKDLDINLAKKMgfdkvYQITSQTYDRKFDSSILNflsNLAQSAHKITNDIRFMQH-----LKEIeeHFEPHQIGSSAMPYKRNPIYSERIASLAKFIMSLQSSGGFIAATQWLERTLDDSACKRLNIPQAFLAADATLILLSKVFNNIRVNKKMIEKHVktempfiltEDILMKATknGGDRQILHEKIriySMKVKENIYSGTTendLIKLILNDQsfKLTSKDIDEILNPNE-----------------
>UniRef50_Q9Z4S3(47-385:398) Argininosuccinate lyase n=8 Tax=Thermotogaceae RepID=ARLY_THENN   E=5e-20 s/c=0.30 id=23% cov=52%
--------------------------------------------------------------------------------------------------------------------------------------------ARSRNDQVLTALRLMYKDELKKIKDLVVELQKSLDGFIERFGQIKFAGFTHTRKAMPTDFATWAGALRDALQDDLKLLETVYDIIDQSPLGTGA---GYGVPIEVDREFT---AKELGFS-RVQWNPIYTQNSRGKFeyLLLH-VLSQISYDLNRFASDIIFFS---LPEIGFLKLPkELCTGSSIMPHKINPDPLELVRAyhhfvVSRMVM----AVSL-PSNLILGYHRDLQLLKKPVIESIDVVKNILRIMKI-IFDRIEVDREKSED---------------------------------------------------------------------------
>UniRef50_Q2H905(50-385:436) Putative uncharacterized protein n=2 Tax=Fungi/Metazoa group RepID=Q2H905_CHAGB  E=2e-19 s/c=0.30 id=19% cov=65%
--------------------------------------------------------AFARANWKAGIISEDEFQAIERGLLQVMEEWKQ-------------GTFAIMPNDEDIHTANERRLGEVIGKDIA----GKLHTGRSRNEQVVCDMRMWLRDRIREIDSQLVAFLKVIITRAESEIDYIMPGYTHLQRAQPVRWSQWLMSHAAAFKQDLERLRQVFERVNLSPLGCGAL---AGNPFRIDRNAIAEELGFSGITL----NSMNTSADRDFLLDFLVWNSIFTNHISRWAEDLVIYST---SEFSFVRLaDAYSTGSSLMPNKHNADSLELLRGKsgpCFR------------SNGW--------------------VNDGI---ANGVIATLKVRPERMAAALDKT-MLATD------------IAEWLVRRGCPFREA-------------------------------------
>UniRef50_A4WYP6(113-461:520) Argininosuccinate lyase n=5 Tax=Rhodobacteraceae RepID=A4WYP6_RHOS5   E=2e-19 s/c=0.29 id=22% cov=64%
--------------------------------------------------------------------------------------------------------------------------------------------GRSRNDIGATLDRMAVRETCLALLAEMEATRRACLEAAGRHVLTVMPGYTHLQPAQPITFGYYLANVAQGMEREHERLAAVLDRADACPLGSAALaGTSFPIDRD-------ETAALLGFA-RPAVPGLDAVASRDFVTELLWAVTSAQVLFSRVAQDLYTFTTWE---FGALSFPDRVAGtSSIMPQKKNMLPLEYFRAEAGRSIGALAGALSAVKGSNYSigLDSVREGVADAWPAFARF--RAALPLLRLILETATPDAEkllqRCKANFSTATDLADGLVRDFGisfrdaHHVVGRAVQRVLATGGGAEDLTVEvlnaaaedeigrRFDLPEERLRRWMDP-------------------
>UniRef50_D1CE80(103-384:448) Argininosuccinate lyase n=1 Tax=Thermobaculum terrenum ATCC BAA-798 RepID=D1CE80_THET1  E=5e-19 s/c=0.35 id=26% cov=40%
-----------------------------------------------------------------------------------------------------------------------------------------IHTARSRNDQVLVDLRLYAKAKILELESALLQCAESLVEFASKHEHVPMPGYTHMQRAMLSSVGTWAGAFAEALLDDLKLLETAYELNDQSPLGSAAsYGVPLPIDRQY-------VADKLGFAKVQ-NNVLYAQNARGKFeALVVQAISQIMLDLSKLAQDI-LLFTTAEYGFFTISDSFV-TGSSIMPQKKNLSMMELI----------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q3JSA0(537-803:914) Argininosuccinate lyase domain protein n=28 Tax=pseudomallei group RepID=Q3JSA0_BURP1  E=1e-18 s/c=0.37 id=22% cov=54%
-----------------------------------------------------------------------------------------------------------------------------------------VHTARSRNDINACVAKLRAREWFDTCGGKLWRVRAAIVDKAQHTLDWPLPTYSQYQAAQPGSFGYYLWSVETALRRDQAALERLDEELAVCPLGAGA---GAGTDFPIRPGVSAAL-----LGFARSfDSALDAVASRDLVLHFLAAIAIASTTLSRLAHDLQLWT---MRETDFLALPdELSGGSSLMPQKKNPYLLEIVKGKLAHVAGALNAAVFASQRTPFSNSV---EIGTEMLAPC---ADAVQAFGESCdllrlmVSGVTGDPAKMRAAAEAGLVSAT-----------------------------------------------------------------
>UniRef50_A1RR78(31-415:429) Argininosuccinate lyase n=5 Tax=Thermoproteaceae RepID=ARLY_PYRIL   E=1e-18 s/c=0.25 id=27% cov=54%
---------------------------------------------------------------EVGIMPKEAADAILKTLKEATPEQLLSSEF------------------EDIHEALEKWLIDRLGEETA----GWVGLGRSRNDHVAAAIRLAALRKASALRKNVEKMRCILAKKALEYADCAMPSFTHFQPAQAITFGHYLLAVDELAAEFLHVLKAVEKLLKRSPLGAGPAG-GTRTPID-----RERLAKLAGFEDVVENALYASGSRFFALALASAVVSFL-TELSRTVDDLIRWNS-PLVGY--VAAPDSHVStSSIMPHKRNLVTLEVFRARAAEALGHLTAL--------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q123L3(120-454:513) Argininosuccinate lyase n=2 Tax=Burkholderiales RepID=Q123L3_POLSJ   E=1e-18 s/c=0.29 id=24% cov=65%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRIDQGATVRRLYKRNRMLDVMDQLNGLQDAIAQQARRHARTIMPGYTHLQHAQPWVFGHYLLSFSSRLHDSFERLAQAYGRVNRNPLGAvGLAGTSwpLNRMRTTALLGFDGLVENSKLG-REA---YYAAEAIGALAFVMADLNDLAT-------DLHLWSSTEF-GLVE-SDDSYCGTSSIFPQKKNPAGLETIKKAAGSAVTWLATalATFRAEGTGDQAMRELPLIDEALAT-----TEGMLDLFTGVIETLIVHDDRMAESLSGSWCTASNLADVIVRERglsfrqvhhiVARVVRNCIAQGTApadltsalLDEAALETAglelRLGDEAVRDALDPRRFVE--------------
>UniRef50_UPI0001B4D80D(37-329:402) 3-carboxy-cis,cis-muconate cycloisomerase n=1 Tax=Streptomyces lividans TK24 RepID=UPI0001B4D80D  E=1e-18 s/c=0.33 id=25% cov=55%
--------------------------------------------RAYLRALLDAEAALTRAQAALGLAPAEAA----DAVGAVAADPAAFDARSLAERARGGG-------NPVIPLVAdlTKAVGEPYGPY--------VHRGATSQDILDTATMLVAARTLDLLLPDLARTERALARLAAEHRDTPMPGRTLTQHAVPTVFGLKAAGWRALVLDARDRITAVRDAL-PAQLGG-AAGT-LAAFEAYGATDPTALpAAYAGELGLRAPVLPWHT-LRTPIADLAGTLAFTAGALGKIAVDVLTLSRTETGEVAEGGGGGSSA----MPHKANPV---------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q08Q17(55-397:458) Argininosuccinate lyase n=1 Tax=Stigmatella aurantiaca DW4/3-1 RepID=Q08Q17_STIAU  E=2e-18 s/c=0.28 id=24% cov=62%
--------------------------------------------------------------------------------------------------------------------------------------------ARSRNDINATVTRMRLRPALAEVLRQGMLLASQLERLGVAHAQTLMSAFTHLQPAQPATFGHYLGGVLSELLRTLDWIAGAYDTLNRCPMGAAAgVGTSFPID-------TTIVAELLGFE-SPLGNSLDAVGSRDYVVQVLSGLALLGTLLTRMSADLQTWAS---SAYGFLGWPdELVSTSSIMPQKRNAFVLENIRGQAVKATG-------------FLMNTLMGLKSTSFTNSVEVSSEAtspvwpaleaartALVLMELLMSNVIVQPEPMRRFLVGQDTTMTALADHlvarhgLAFRTAHDVVgrlvnlkrepELTPQAARGLLEPLLATTLgrevsLDEAELAQVLEPE------------------
>UniRef50_D2KUG3(114-440:464) Adenylosuccinate lyase n=2 Tax=Borrelia RepID=D2KUG3_9SPIO   E=2e-18 s/c=0.29 id=21% cov=60%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------LKNTIKTLNNFSIKYKSLATLAYTHLQEAQLTTLGKRSCLWLQSLIFDFKELNFILSNLCFRGVKGT-----VGNQSSFKELFSSNFEKVKTLDMRLAQkmgfNKVYAITSQtyDRKIDSSilNFLSNLSQSTHKITNDIRFLQH-----LKEIeeHFEEKQIGSSAMPYKRNPIHSERIASLSKFIMSLQTSGGFIAATQWLERTLDDSACKRLNIPQAFLATDAILTLLNRIFHTIKVNEKIIEQHVkiempflltEDILMKATknGSDRQILHEKIrtySMQVKENIYLGKHennLIKLILNDKsfKLTPKDIDEILNPNE-----------------
>UniRef50_UPI0001B4D944(55-426:457) 3-carboxymuconate cycloisomerase PcaB n=1 Tax=Streptomyces viridochromogenes DSM 40736 RepID=UPI0001B4D944  E=2e-18 s/c=0.26 id=22% cov=67%
---------------------------------------------------------------------------------------------------------------------------------------EYVHRGSTSQDVLDTGAMLVAARTLRIIRADLGRAAEALAELAGTHRDTLMAGRTLAMHAVPTTFGVKAAGWRQLLLDADRRLELVLVAL-PVSLGGSA-GT-LAGYVEYARidgRAAARSGGATDRDDRDRGRDGDSGSDLDvaryvaELTEAFGAETGLAAgpampwhalrtpiadlaaalaftagALGKLAVDVQSLT---RTEVGEVAEPSV-AGrgvSSAMPQKRNPVLATLVRSAALQVPVLAAGLTQCLVT-EDERSAGPWHAEWQLLRECLRLTGGAAHTAVELAAGLEVRPERMRQNVALigsalvSERLAAALAPRLGKAAAkrllSMATELASGSGRPLPEVLAHLpelaGVFAPKELDRLCDPAGYTG--------------
>UniRef50_D2QE84(103-359:445) Argininosuccinate lyase n=3 Tax=Bacteroidetes RepID=D2QE84_9SPHI   E=3e-18 s/c=0.37 id=27% cov=40%
-----------------------------------------------------------------------------------------------------------------------------------------IHSGRSRNDQVLVDMKLFSRDRLWRVAEAVRTVFDRLVSRSEQHKDDLLPGYTHLQIAMPSSFGLWFGAYAEALADDMLTLQTAYRLANRNPLGSGA-GYGSSFPLNRSLT-----TELLGFEGMHVNVVYAQMSRGKTEQTALTALAAVAATLSRMAMDICLYNSQ---NFSFLTLPdALTTGSSIMPHKKNPDVAELL----------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q54J34(125-419:466) Adenylosuccinate lyase n=59 Tax=cellular organisms RepID=PUR8_DICDI   E=4e-18 s/c=0.32 id=24% cov=39%
-----------------------------------------------------------------------------------------------------------------------------------------IHFGLTSQDINNTAIPLSIVESVEKvLIPQLKQsILEPLRQFAQQWKSIPMLARTHGQPATPTTVGKELMVFIERLENQINHLEQSVPHTCKF---GGATGN-LNAHKvsypaidwvVFSEKFVKVLhPSLKRMRFTT------QIEHYDNVASLLDAFKRINTILIDLCRDIWTYIS---MEYFNQKLVKGEVGSSTMPHKVNPIDFE------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A8MCU5(45-391:450) Argininosuccinate lyase n=1 Tax=Caldivirga maquilingensis IC-167 RepID=A8MCU5_CALMQ  E=4e-18 s/c=0.27 id=25% cov=63%
---------------------------------------------------------------KVGVLPSNEAEAIIKALRSLAKEP----YKPSDEYE---------DVHEYIEAVLIHRLGDAGGW---------IGLGRSRNDHVATALRLRLRKLIIELASSIIELRRVVLNKAIETADTVIIGTTHRQPAQVTTLGHYML-YLDELSRDfLTSLLSIYEVVNKSPLGSG--------PLAGTMVKLNRVREAEELAFNGIvENTVYATGSRYFMLASASITVSYLVELGRFINNIEMW-LMPQ--LNYITLePSHLATSSIMPHKRNPATLEVFRARIGEAVGHLVsmySIERPVEAG-YQLDLQEEtrhawLIMRIAIDGVGMITD--------LLRGIKVNEGRVKEDL-------------------------------------------------------------------------
>UniRef50_Q161F2(15-408:443) 3-carboxy-cis,cis-muconate cycloisomerase, putative n=11 Tax=Rhodobacterales RepID=Q161F2_ROSDO  E=5e-18 s/c=0.24 id=20% cov=73%
---------------------------------FPVGEtGRLFSDSAAIRAMLLVEGALAKAQGKLGIIPETSAAAIHRATLEIQIDP------------GALATSTGQN--------GVCVPGLVDAFRAEMNAPEHaqfVHWGATSQDIIDTALMLRLRQALALAESDLSELLSRLAAAAEEHATTPMAARTYGQVATPTTWGAVVAQWGMPLADALDALPHLRQSSLFVSLSG-ASGTSAALGAQ-APDLRRALAA--GLGLQDPERSWH--TDRTPLLRISDWLGHVATILGSMGSSLNGLAA---SGIDEVAFDRRGA-SSTMPQKQNPIAATGLVALSNQSCALRAGMTSAAQHRH-QRDGTAWFSEWMLLPQIVLTTASALQIATGLAGEVQPNVAQMQAGLETGNGLI------------------------------------------------------------------
>UniRef50_B9NWJ1(102-291:355) 3-carboxy-cis,cis-muconate cycloisomerase n=1 Tax=Rhodobacteraceae bacterium KLH11 RepID=B9NWJ1_9RHOB  E=5e-18 s/c=0.50 id=22% cov=40%
-----------------------------------------------------------------------------------------------------------------------------------------IHTGLTSQDVMDTALILTLKAANQLFRQRLEQLEQTLTDLDRRFGENKMTGRTRMQLAHGIRVHDRLGIWQRPLVEHQCRLTEIESRLLRIQLGG-AVGD-RAAWQGAGQNVADALAKLLDLAPAGTAWH----SDRSALVEYAGWLALVTGSLGKIGQDISLMAQQ---GIEEISI-AGGGSSSAMPHKQNPIGAELL----------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q73MK9(46-306:480) Adenylosuccinate lyase, putative n=1 Tax=Treponema denticola RepID=Q73MK9_TREDE  E=5e-18 s/c=0.36 id=20% cov=53%
--------------------------------------------------MAIVKAHLKIAEEKKGSLLPKLSGELEKTLDDIALNID-----PSEVYEEEHKTQHN------IRALVNVLKKKVPENTAPL-----VHLGATSADILDTAFSMRIRDAvIKVIIPLLKKTELLLCDIAEREAETPQVGRTHGQHAVPITFGYAVSEYVARLGKSILKMEDLVKDLR--GKFAGAVG-AYNAaslivsdPMRFEKIYLDYL----GLKPSEYSH---QLVEPEYMLRLLLEANIAFGIIANLADDLRNLQ---RTEIGEVFeyFSATQVGSSTMPQKRNP----------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B0U0M0(105-393:397) Argininosuccinate lyase n=2 Tax=Francisella philomiragia RepID=B0U0M0_FRAP2  E=7e-18 s/c=0.33 id=25% cov=40%
-----------------------------------------------------------------------------------------------------------------------------------------IHTGRSRNDQSLVMLRLFMIDKIQFLEKTIQENIYTLRSKASKFKNIPMPGYTHMQKAMPTTVATWLGSFADALADTLLLISATSKVINQNPLG-SASGFGISNFKHDKEYT----TELLGFN-RTQDNPIYCACSRGYFEKL--ALQTFSNPIsiySRFANDMMLFT---MAEFDYFSLSnSYTTGSSIMPQKRNYDLFEIM----------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B6HHB0(42-411:483) Pc20g14240 protein n=8 Tax=Fungi/Metazoa group RepID=B6HHB0_PENCW   E=8e-18 s/c=0.26 id=22% cov=67%
----------------------------------------------------------AEAQKELGL--PISAEAIEQmKAHQVIQ----DDEFAV------AAEEEKRRRHDVMAHV---------HAFGLVAPAAAgiIHWGATSCYCTDNADLILLRDGLDILIPKLAVVVDKLSQFAQKYKDLPCLGFTHGQPAQLVTVGKRACLWIQDLLMDLRNLERARDDLRFRGVKGTT-GTQAsflqifNGDHAKVESLDELVTEKAG--FSSAFIISSQTYSRKIDVDVGNALGSFGATCERIGIDIRHL-----AMLKEVEEPfeKDQIGSSAMAYKRNPMRSERLCSLGrhLQNLPKDGLDTYSAQ--WFERSLDDSAIRRISIPELYLTADACLILLNNVSSGFVVYPEVIKRHVNDEL---------------------------------------------------------------------
>UniRef50_B0R3B3(118-456:458) Adenylosuccinate lyase n=10 Tax=Halobacteriaceae RepID=B0R3B3_HALS3   E=1e-17 s/c=0.28 id=21% cov=62%
------------------------------------------------------------------------------------------------------------------------------------------------------------------LTPELRGLRDDLVSFAHDYADLPMLARTHGQPATPTTFGKEMAVYAARLGRALARITDAVDGLTGKLAG--ASGTWAahtAAFPDvdwrsFAARFVDSLGLAYAEPTTQVNPCDDLTAVFDAVAGANGVLEDLAVDAwLYVSQ--RYLGQDAADG---------ETGSSTMPHKVNPIDFENAEGNLAKANSDLGFLGDSLTTSRLQRDLSDSTVKRNIGAAFAHCLLAYRKLGD-GLDAVTPNEAVLREDLRANPEVIgeavqTILRRE-GHDDAYERVK-ALTRGERVSlddfKELFASLDIDADTRDELLAltPERYVGVAADIAR-------
>UniRef50_A7EF71(54-409:437) Putative uncharacterized protein n=2 Tax=Fungi/Metazoa group RepID=A7EF71_SCLS1  E=1e-17 s/c=0.26 id=16% cov=72%
--------------------------------------------------------AWARANHKNGILTEAEFAAIESGLKQV-EEEWVAGTFKIVP---GVDEDIH-TANER---RLGEIIGKEIGGK--------LHTGRSRNEQVATDMRLWLRDELKKIESFLVDYLKVVAARSENEIEHIMPGYTHLQRAQPIRWSHWMLSYGLAFATDLQRLREVIKRVNRSPLGCGALaGNPFNIDR-------EAMAKELGFEGLL-WNSMSAVGDRDFVVETMQWGATLMSHLSRWAEDLIIYGTGE---FSFVRL----------------------------------ADAYSTGGLPSTYNKDLQESVEPMLDHIKTVGDSIQI-ATGVLSTLTINPEKMKASLD-PFMLATDLADYLvragvpfreTHHISGQVVAYSEKTKIPMDQLTYDQlksiDSRFKEDVSECFDYEK-----------------
>UniRef50_P21265(123-465:485) Adenylosuccinate lyase n=167 Tax=cellular organisms RepID=PUR8_CHICK  E=2e-17 s/c=0.27 id=20% cov=64%
------------------------------------------------------------------------------------------------------------------------------------------------------------------LLPKLARVISRLADFAETHADLPTLGFTHYQPAQLTTVGKRCCLWIQDLCMDLQNLERARDDLRFRGVKGT---TGTQASflqlFEGDHSKVEELDRLVtaKAGFKRSYMVTGQTYSRKVDIEVLSVLASLGASVHKICTDIRLLAN-----LKEIEEPfeKDQIGSSAMPYKRNPMRSERCCSLARHLMTLVLDPLQTASVQWFERTLDDSANRRVCLAEAFLTADIILSTLQNISEGLVVYPKVIDRRIRQELPFMATENIIMAMVKAGGNRQDCHEKIRVLSQqaaaVVKQEGgdndfiarvradpYFSPihEHLDSLLDPSSFTGraPQQVAKFLKEE---
>UniRef50_C8NQR2(93-346:368) 3-carboxy-cis,cis-muconate cycloisomerase n=4 Tax=Corynebacterium RepID=C8NQR2_COREF  E=4e-17 s/c=0.36 id=23% cov=52%
-----------------------------------------------------------------------------------------------------------------------------------IHP------GATSQDIIDTSLMLCLRDATGEIIADLGELAELLAELTRTHRDTPMMAHTLGQQAVPTTVGCITAGWLQAVLRSRAALQELRFEVSY----GGAAGTMTATHPH-GFAIQDELAAELGLhnsGLVWHSDRIPVTTIAAALATAAGAVR-------KIAGDVIFLSASEISELRE-----AQPgGSSAMPHKANPAAAIACDGYARRVPGLLATL-FDALDCRLQRGT---GSWHAEWQTIRELAAATASAVGRCrrsIDGIVVDTGRMREHL-------------------------------------------------------------------------
>UniRef50_P30566(122-459:484) Adenylosuccinate lyase n=48 Tax=cellular organisms RepID=PUR8_HUMAN   E=4e-17 s/c=0.27 id=22% cov=65%
---------------------------------------------------------------------------------------------------------------------------------------------------------IILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGT---TGTQAsflqlfegDDHKVEQLDKMVTEKAG--FKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLAN-----LKEMEEPfeKQQIGSSAMPYKRNPMRSER----CCSLARHLMTLVMDplqtASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQqaasVVKQEGgdndLIERIQVDAYFSPihsqlDHLLDPSSFTGRASQQVQR
>UniRef50_Q3MNP2(96-295:401) Beta-carboxy-cis,cis-muconate cycloisomerase n=1 Tax=Terrabacter sp. DBF63 RepID=Q3MNP2_9MICO  E=1e-16 s/c=0.45 id=21% cov=40%
-----------------------------------------------------------------------------------------------------------------------------------------VHRGLTSQDVVDTALVLLARDALVRMGDDLAATSRALAALAGRHRSTLMVGRTLTQHAVPITFGLKAAQWLAGVLDAVAQVDDILGTLPV--QCGGAAGT------------LALVGELTDEPLAAARAFADELAldwpgvpwhtNRSVITRIGSAVVSTCDALGVVAADVSTLSRPEIGELREGTV-AGRGGSSTMPHKRNPVLSVLIRSVALQ----------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q11FS3(119-411:510) Argininosuccinate lyase n=2 Tax=Proteobacteria RepID=Q11FS3_MESSB   E=2e-16 s/c=0.31 id=25% cov=44%
--------------------------------------------------------------------------------------------------------------------------------------------GRSRIDQGATFRRLYERQAIIAVLTELIDLEAAVIAQAANHIDTIMPGYTHLQPSQPWVFGHYLLGVAERLDIDLVRLERAYAAVNLCPLG-TVGGSGSTWPLD-----RHRVASLLGFDgIVENARLGRDIQYTGDIA---AAASMLMATLNDLATDLQLWSMQE---FGFVELDAGYCGtSSIFPQKKNPVALEGVRSAAAgavQWVGNVLAVSRGVGSGDLAL---------------------------------------------------------------------------------------------------------------------
>UniRef50_D1S4X8(98-283:484) Argininosuccinate lyase n=1 Tax=Micromonospora aurantiaca ATCC 27029 RepID=D1S4X8_9ACTO  E=3e-16 s/c=0.48 id=28% cov=38%
-----------------------------------------------------------------------------------------------------------------------------------------VQLARSRNDLDAGVFRMVLRDQLLQVLDALLATGRTVLDRADRHADVVITGYTHRRPAQPTSIGHVFAGYAEALAGEAAAYAGLLDEMNRSPLGSCAfAGTDLDISPR-------RLADLLGFD-QLIVNSYEAVAGADHLVRV-ATLNAQALATgARLARTLMdWLSWGWVVTPGEFT-----QGSSIMPQKRNPVVLE------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6DT96(107-296:431) Argininosuccinate lyase n=1 Tax=Lentisphaera araneosa HTCC2155 RepID=A6DT96_9BACT  E=4e-16 s/c=0.47 id=24% cov=39%
-------------------------------------------------------------------------------------------------------------------------------------------MARSRNDQVVSATRLFGKDKLIKIKHTLKSFIEELLNLASKYETTPMPGYTHTQRAMPSSIGLWASSFAEILINQKETIDAAI-SLNDVNVLGSAAGYGTDFPID-REFVTKDL----GLARTQVNSLSCQLSRGQVECQTLQSLWGTMFVINRLANDMVWMTS---AEFDFLDVgKSCTTGSSIMPNKKNLDPCE------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q1D262(3-334:449) Argininosuccinate lyase n=2 Tax=Cystobacterineae RepID=Q1D262_MYXXD   E=4e-16 s/c=0.27 id=27% cov=61%
---------DTLWGKGLPLDA--------AIHRFTVGNDPVVDLALAPHdALGSAAHARMLA--RVGLLKDAEAKSLVTA-LKALHDEARAGTFVIRPEQEDGHT-------------ALEaALVERVGE-----PGKRIHLGRSRNDQVQLALRLLLREEVLTLGARAAELAGAFLDFAQAHKDVALPGYTHLRRAMPSTFGLWGMAFAEGLLEELEALRGVWARLDRCPLGA-AAGFGVPLPID-----REYVAALLGFS-RVQRSPIDVQNGRGRHeSAVLGWACSVAGTLEKWLWDVQLYSMDE---FGFLGLPdAYTTGSSIMPQKKNPDVVELARGRC------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q11F19(106-429:499) Argininosuccinate lyase n=2 Tax=cellular organisms RepID=Q11F19_MESSB  E=5e-16 s/c=0.27 id=19% cov=54%
-----------------------------------------------------------------------------------------------------------------------------------------IHLGRSSADLAGVSRRIVLRTAVLSMARQLIDVQLTILNTAPDHLDCIIPAYTHGQPAQPTTYAHWLMMWANVFHRDTQRLLGGLDRLNLSPAGA-AVATG----TDFAID-RSRVATLLGFDGIL-VNTMDATLSNDVFAEYVSIFSLLCANMGRLAEDLLFWSTQE-AGI------AVIPdrfcdTSSIMSQKRNPSFLHEL-----RAMGAEAASTLLLVSGT-EFGTTGQSV-----HARKTAENAVWALVGKiikrlpqmadLIASTEIDPQRAMRLTENSWSQATdvasALVRHLG----------------------------------------------------------
>UniRef50_C2ANG7(95-428:446) Adenylosuccinate lyase n=1 Tax=Tsukamurella paurometabola DSM 20162 RepID=C2ANG7_TSUPA  E=6e-16 s/c=0.26 id=20% cov=66%
-----------------------------------------------------------------------------------------------------------------------------------------VHRGLTSQDVMDTALMMLARRVADEVAEDLAAVSAALARLADEYADTSQVGRTLGQFAVPITFGAKVAGWRQGIDGAARRLAAAGTPVQC----GGAAGTNAAVVAMGVDPVQAGAQWARKLALTPSEPWH---TSRGPVAELGDALAAVCAAAGRIANDV-IQASRP--EVGELAESAVdRGGSSTMPHKRNPVLSVLIRAAALSAPGHAGVLQLAAGQAEDERStgawhaewpalRSLLRLALGTAESLRELCEHLRVFPDRMAQRVTAAAP---LLVSERLMIVLAERARGGRAAVQAAIDAAVAAPVDDRAAVLREGIsgavpgLTAAELDELLAVDGYLGTA------------
>UniRef50_UPI000050F815(27-437:467) 3-carboxy-cis,cis-muconate cycloisomerase n=1 Tax=Brevibacterium linens BL2 RepID=UPI000050F815  E=6e-16 s/c=0.21 id=21% cov=82%
---------------------------------------------ALVSALGDVETAWINAQAHAGLISadarAEAVEAIAATTRSLLADSAELETLAADAESGG---------NPVIP--FLKAVRSPLGE----DASRALHKGLTSQDVMDSALGLLMARVARQTHARLDVIAELLVGLSEAHADTVCLARTLTQPALPTTFGLKIASWAAEVHE----VQSLTPRIDYVQVGG-AAGT-RAAIREFAGTQTETLLREFHVQLRGPD---AALTSipvpwHTDRVRVLNWASHLTQCVtvgASIARDVLI---GTRPEVGELALAATG-GSSAMPQKLNPTSAVLLHRNGMRAPGLMATLTSTAAEAIEERSDGAWHAEWPALSELMGLAVSSLIMLQTMVEGLSVNPEAMRKNVDaASPGIfAERLNIAFGdRLSKAEVQEIINPGGVPVAalTAALEKHPTEDEEtldLAGFFSPENYLG--------------
>UniRef50_C4DQU1(68-358:454) Adenylosuccinate lyase n=1 Tax=Stackebrandtia nassauensis DSM 44728 RepID=C4DQU1_9ACTO  E=6e-16 s/c=0.30 id=20% cov=57%
-----------------------------------------------------------------------------------------------------------------------------------------VHYGATSQDIMDTAMMLVAHRATAVIVDNLAHAAEAAASLTERHRDTLLIGRTLGQHAAPTTFGAVAAGWLSGIDAARDQLRSARFEL--AAQLGGPVGTlepygtqGLRVLADFAHRL--GLAD-PGLPWHTE---------RTRVTRLASALATGAGTLAKVAHDVSVLGS---SDVGELR-EGSGGGSSAMPHKHNP--ADSVL-----VLANvrrtpgLAATMFAALESELQRPAGAWQSEWQTLSQLLRCCGGASSRASSLLSGLRVDTGRMRSHLDATGGLLRAgavadqLAPALGRREAHElIADLAAR---------------------------------------------
>UniRef50_A2BJL5(104-409:465) Argininosuccinate lyase n=1 Tax=Hyperthermus butylicus DSM 5456 RepID=A2BJL5_HYPBU  E=8e-16 s/c=0.29 id=24% cov=63%
--------------------------------------------------------------------------------------------------------------------------------------------GRSRNDHVSAALRLYTINKIIDTLYWLLQARLRLIELAEKHRGAPVLFHTHQQPSQLATLDCLLLAWEEALASAYKLLYSVIGLVDRSPLGASA-GAGTLAPID-----PEELARLTGFSGVLGNSLY-ATGSRLDVTAAALAATALLVEASRIAENLVLL-STPY--VSAVRIPESHvATSSIMPHKRNPVTLEVLRARAARAAGLAAGLLAIQKGLPYGYNLDLQE-ANPLLYTI--LRDAAESSRilADLFSSMEFDLERLSKLAES----------YIAW--GAELAElLALRTGMPLREAYREVAMkLRDGKISELFQKLGVTSPS------------
>UniRef50_C7MHE6(128-464:823) Argininosuccinate lyase n=1 Tax=Brachybacterium faecium DSM 4810 RepID=C7MHE6_BRAFD  E=2e-15 s/c=0.26 id=21% cov=68%
----------------------------------------------------------------------------------------------------------------------------------------DVQLARSRNDLDAGVFRMILRRGILDLAELLLQAVRDLEEAAARTVDALLIGHTHRRPAQPTTIAHVLSGLAEAFLSQAEELLSVYDEMNVSPLGSAAfTGTDIAID-------AQRVADLLGFssSFTAS---YEAVAGAEHFMRLAGLHARIASTGARWA---RVLQ--EWMNLGWVRMPdEFTQGSSIMPQKKNPVVLEHLVSMSGAANGETNAVYTTIAAGWYEdsNNATTDVQKH-LWSSTERIIRFVR-LIDGLTLEIEPAAlpsdEDIVRSGATTTAVAEALATHsVPWRSAHDVVGTLFRQGDpTTWDEGQVEAALAEAAIDDDGRLRDLVLSSGRDPRRILEREQ
>UniRef50_D2R2V1(115-428:476) Adenylosuccinate lyase n=6 Tax=cellular organisms RepID=D2R2V1_9PLAN  E=3e-15 s/c=0.27 id=19% cov=63%
---------------------------------------------------------------------------------------------------------------------------------------------------------ILMREALELIARRLAVVIDALGKFATTHRELPCLGFTHLQPAQPTTVGKRATLWIYDLALDLAEIEHRIESLRARSVKGT---TG--TQASFLALFHGDHAKVRQLEAMVAERMgFSGSYAVTGQtytrkvdAQIVDTLSGVAQSAHKLASDLRLLAS--RKEMEEPF-EANQIGSSAMAYKRNPMRSERVCALARFVMSLQSSPAATLATQWMERTLDDSANRRLVIPQAFLGIDAVLLLLTNISSGLVVYPKTIAANLNAEL-------PFMASENLMMAAVERGGDRQELHEVIRAHSQAAALDVKQEGKPNTLLerlrgEPAFAG---------
>UniRef50_D1BFI0(170-472:488) Adenylosuccinate lyase n=4 Tax=Actinomycetales RepID=D1BFI0_SANKS   E=5e-15 s/c=0.28 id=23% cov=59%
-------------------------------------------------------------------------------------------------------------------------------------------------------------------LPAATALVEQISEMAREHASVPMLSRTHGQPATPTTVGKELAVLAHRLRRQVRRVEGA-EYLGKLNGATGTYGAHLAAVPGTDwPAVSKAFVEGLGLTWNPLTTQIE---SHDWQSELYADIARFNRILHNLATDVWTYIS--LGFFKQIPVPGA-TGSSTMPHKVNPIRFEnaeanleiscalldtlSATLVTSR-MQRDLTDSTT------QRNI-GPAFGHSLL-AIDNVRRGLKALAVNgdlLADDLDANWEVLGEAV-QSAMRAASVAGVEGmenpYERLKELTRGHRIDGDDLRAFVAGLGL--PDDLAARLS--AMT---------------
>UniRef50_B2KEG4(144-463:463) Adenylosuccinate lyase n=1 Tax=Elusimicrobium minutum Pei191 RepID=B2KEG4_ELUMP  E=5e-15 s/c=0.27 id=21% cov=60%
------------------------------------------------------------------------------------------------------------------------------------------------------------------LLPELKKIHKELTDLSKKYASTIILARTHGQAAVPTTFGKEFKVFEYRLRRQIKQLEKQQISCK---LGG-AVGN-FNAHfaafdkvnwHSFAKKFISGFNKGRGVKIFL--NEVStQIDSHDTYAELFDNVKRANTILLDFCQDMwRYISDDyikqrPVEG---------EVGSSTMPQKVNPIDFENAE-------GN---IGLANALfGYFSSKLPVSRLQRDLSDS-TVSRNFAVAFgysvvaysaILKGLGKISVNTQKCAQALhEHPEVLAEGVQTILracGIQNPYEKLK-ALTRGKKIDNEVLRRFIedldVSKEVKDKLkkLSLEQYTGIAAKLAKGLK----
>UniRef50_B8LE99(133-388:497) Adenylosuccinate lyase n=1 Tax=Thalassiosira pseudonana CCMP1335 RepID=B8LE99_THAPS  E=7e-15 s/c=0.33 id=24% cov=49%
---------------------------------------------------------------------------------------------------------------------------------------------------------IQLKEALKLVQRKLVQTIAILKDFAEKHKDLPTLGFTHYQPAQLTTVGKRCTLWIQDLLMDYERVTYELENLPMRGVKGT---TG--TQATFLELFngdhdkVKQLNE-----------KVCAMMGFTKCVPVSGQtytrkidyhilslLSGIAQSAYKMCGDIRLLAN-----LKEVEEPfaKNQIGSSAMAYKRNPMRSERVCSLSRYVMSLPPSAANTHANQWFERTLDDSAIRRIILPEGFLAVDVVLNLLMNIADGMVVWPNVVEKHVMEEL---------------------------------------------------------------------
>UniRef50_B6KC85(168-489:500) Adenylosuccinate lyase, putative n=8 Tax=Apicomplexa RepID=B6KC85_TOXGO  E=8e-15 s/c=0.26 id=23% cov=59%
----------------------------------------------------------------------------------------------------------------------------------------------------------------QHLLPAVDDLAASLHMRAVEFAEVPMLSLTHGQPATPSTFGKEIANF-------EWRVKNAIKRVRDVEFRGkynGAVGCFNALVVADAKVAWPEVArdfvESLGLTYQPYSTQIEQ---HDWIAELCDALARLNSILLDFSRDMWLYIS--RDVLK-LRVVAGEVGSSTMPHKVNPIDFENAE-------GN---LELANALLRF-LSTKLPVsrMQRDLSDS-TVLRNVGVAFghclvayesAKKGLDRVDVNSEKMLKELDENWAVlgepVQTLLRKRGVRNAYEKLKSATRgqdiDKERMQDIVETcSKDLLPEDLEILrsLTPATYTGLA------------
>UniRef50_B6WB77(2-215:310) Putative uncharacterized protein n=1 Tax=Anaerococcus hydrogenalis DSM 7454 RepID=B6WB77_9FIRM  E=1e-14 s/c=0.39 id=24% cov=36%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KRLQENPLGACAmAGTTLPTD-RFIT------TKLLGFD-KPTENAMDTVGNRDNIMDYLYLSSLTMTHISSIAEEFVVFNSQE---FSFIDIDDGYcTGSSIMPQKKNPDLAELARGKVGRNIGNLINLLTVVKGTFLTFNKDFQEDKEALFDSIKTLNMSLLIF-EKMLEGSHFKEEVLKKHLEE-----------------------------------------------------------------------
>UniRef50_Q21774(118-424:478) Adenylosuccinate lyase n=3 Tax=Caenorhabditis RepID=PUR8_CAEEL   E=1e-14 s/c=0.27 id=20% cov=59%
---------------------------------------------------------------------------------------------------------------------------------------------------------IAYRDSIDHILKRFATVIDRLAAFSLKNKEVVTVGRTHYQTASLVTVGKRGVLWAQELLMAFQSLSEFRDKMRFRGIKG-ATGTQDSFLTLFAgdESKVEALDELV-TKKANFSNRFLITGQTysrqqDSQLVFSLSLLGAAAK--KVCTDIRVLQA-----FGELLEPfeKDQIGSSAMPYKKNPMKSERCCALSRKLINApQEALTILADQG-LERTLDDSAGRRMLIPDVLLTAEALLTTLQNIFEGLSVQTDNVKKIVEDEIA-------FLGLEKAMMMLteegvdrQQAHAV---IRKTALEAKQLQATQ--------------------------
>UniRef50_C7Z8U2(142-438:509) Putative uncharacterized protein n=1 Tax=Nectria haematococca mpVI 77-13-4 RepID=C7Z8U2_NECH7  E=1e-14 s/c=0.28 id=19% cov=52%
---------------------------------------------------------------------------------------------------------------------------------------------------------ILMREAMDLLLKKLAKVISNLSAFALKWKEEPTLAYTHLQAAQLITVGKRAAQWVQDLMFDLESMEQVRKDLK---FRGAQVGTT-GTQASFLEIFhgdsakCDKLNDLLCKKFDFPACYDVSTQTYTRKVDlvVANAVAGLGATAQKICGDIRHLAH-----WKEIEEPfeKSQIGSSAMAYKRNPMRSERVYSLARELMSKPTNFANTLSDQWAERTLDDSAIRRIDIPEMFLLAEAILIGLDNISDGLVVYPKRINARVQEEL---------------------------------------------------------------------
>UniRef50_UPI0001AF7079(93-289:409) PcaB n=2 Tax=Mycobacterium RepID=UPI0001AF7079   E=1e-14 s/c=0.42 id=21% cov=38%
-----------------------------------------------------------------------------------------------------------------------------------------IHRGLTSQDVLDTSLMLGMRSVADHVITQLAQQITTLSALAGAHRGTPMVARTLTQHAAPTTFGAKAAVWLNGVVDAYLRLGA----LVTPAQFGGAVGTWSATtelaslltataePAELAERVIRSATTTLGLRVRLPWHTTRtpVTAAADALVGCTDCW-------GRIAADVITMVRPEIAELGE---PAGGPrgGSSSMPHKRNPV---------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C3BDI7(112-446:502) Argininosuccinate lyase n=1 Tax=Bacillus mycoides Rock3-17 RepID=C3BDI7_BACMY  E=2e-14 s/c=0.25 id=19% cov=64%
------------------------------------------------------------------------------------------------------------------------------------------HMDRSRNDFQACAQLMFAREQVFLIIEDLFEFIDVVHHVSELTSSMLMPGYTHYQAAQIISPGFYLSAVTEQVIELLKNLLFIYNRINKSPLGSGAM-SGLELEWD-----RQNMAKMLGFDNIQNHALI-SVASREWALRVAGELSTFSVFLSRFVTDLIQWGSGE---YGFIDLPDQLSGiSSAMPQKKNFTILERIRGKTSHISTYYLDLIMG------QRNtAFTNLVEiskeanSNLITLFKTTRSILKIFTTVM-ENIEFKEERMKEICINeyfgGFALANCLTLHEGipYREAQAIVgryivlvmdnqlKPSEVNYKLLEQVCQDQGYqinLSENLIRKAFDPQQ-----------------
>UniRef50_D1W006(212-481:544) Adenylosuccinate lyase n=2 Tax=Prevotella RepID=D1W006_9BACT   E=2e-14 s/c=0.31 id=23% cov=38%
-----------------------------------------------------------------------------------------------------------------------------------------IHFGLTSQDINNTSVPLSIKEALhEVLVPCIEELIEQLEAYAAQWKDVPMLAKTHGQPASPTRLGKELMVYVYRLREQLMLLETCKMSAKF----GGATGN-YNAHhvaypaidwKDFGNRFVQ---EKLGLQREQYTTQISNYDHMGAFFDALRRINTIVLDMDR---DFWMYIS---MEYFKQKIKAGEVGSSAMPHKVNPIDFE------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C1DL35(131-428:532) L-aspartate-like protein n=1 Tax=Azotobacter vinelandii DJ RepID=C1DL35_AZOVD  E=3e-14 s/c=0.28 id=22% cov=58%
-----------------------------------------------------------------------------------------------------------------------------------------VHSGRSRQDILAT-YRLATLrRQVLDYAAAMNATRQRLLDIAARNADTLVPAYTNGVQAMPITYAHYLLAYAASFDRDAQRIRELYARLNRSPMGSAVLANSawpLN---------RERLARLLGFDEVR-ENSLDSSQvsSYDIPIEAVDIAANSAIRVGALIGDI-------HTQYHQIRpwllLDEGSTyTSSAMPQKRNPGLLMRVRESASDTVGLAEAVTLRAH------NVTTGMTDYKFaFDSLGVFDAATDMFKgmDNVLDALTINAARAREELENewttSMELADTLqrahqVPFrIGHSFASLIVEEARNEG-------------------------------------------
>UniRef50_D1VC10(90-285:414) Fumarate lyase n=1 Tax=Frankia sp. EuI1c RepID=D1VC10_9ACTO   E=4e-14 s/c=0.42 id=23% cov=39%
-----------------------------------------------------------------------------------------------------------------------------------------VHRGLTSQDVIDTSLVLLLRDVVDRIRAQQRDQVGALAALAHTHRGTLLAGRTLTQHAVPTTFGLKAAGWLTGVLDAAE----ALDRVALPAQFGGAAGT-LSAAVELARRrgHADPVAAVSGavadataaLGLRPARPWH---TTRTTFTALGDALVAGTDAWGRIATDVATLSRPEIGELAEPAVPGRG-GSSTMPHKRNPV---------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A0QIE8(93-289:408) 3-carboxy-cis,cis-muconate cycloisomerase n=8 Tax=Mycobacterium RepID=A0QIE8_MYCA1  E=4e-14 s/c=0.42 id=22% cov=39%
-----------------------------------------------------------------------------------------------------------------------------------------IHRGLTSQDVLDTALMLGVRALADDLIAELREQIRVLSGLTDRHRATHMVARTLTQHAAPTTFGAKAAGWLNGV---LDAFDNVIALVTPVQIGG-AAGT-LAASTELAalrtgtvdpAAVSVELARGTAAALGLAPRPPWHTA-RAPITAAADALVGCTDSWGRIAADVVTLARPEIGELGE---PATATrgGSSSMPHKRNPV---------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A0K2D1(80-464:501) 3-carboxy-cis,cis-muconate cycloisomerase n=3 Tax=Arthrobacter RepID=A0K2D1_ARTS2  E=6e-14 s/c=0.21 id=19% cov=68%
-----------------------------------------------------------------------------------------------------------------------------------------VHASLTSQDVLDSALMLLARNAVTALMTDVRAITTALAVFAEQHADTLCVGRSLTQHSLPFTFGlkaaQWFHGLAAAARRLEAVELPLQTGGAAGTLAAGTVLTKGSVDTPFDLS--GNLAAHLGLAVAPGPwhtNRLAVTSLGDALAAVTDA-------LGKIAGDVLFLSRPEVGELAE----PRAAGrgvSSAMPQKQNPVLSVLVRSAALQAPGQAAQLHLAAANFNDERPDGAWHSEWPAFRQLLRLALGAAGHLRELAEGLQVFPAAMRRNLELSGplllseGVSAAVAPLLeerdgrtGKQQLQDVVDRTLQappaeqsgTYRRLLREAVPASALSDEQLEELLDPASYLGQAGEISRRI-----
>UniRef50_A9HXU4(110-407:469) 3-carboxy-cis,cis-muconate cycloisomerase n=3 Tax=Burkholderiales RepID=A9HXU4_BORPD  E=8e-14 s/c=0.27 id=21% cov=58%
--------------------------------------------------------------------------------------------------------------------------------------------GTTTQDAVDTAHAVLTKTALAALLDELQKLAAALRALAHAHAATPMMARSLLQPAQVTSFGFKCAQSAGALQRSASQLCTLAPHALCVQLGG-AVGN-RAAMGHRAAQVELVLAAELGL---WASGQSWHTQ-RDAWMRLAMEASVCAGSLSKLARDWSLMS---QFEVGELAEAPRGRTSSAMPHKRNSVHCMqaiALTQpvpgLAASLLG---AMTQAHERAmgewQAELSVWAPLWRR---------VHGAAAALRLAADGLRVDAARMQSHIDAlyqvifSEACTDALAPITGREAAQQaiehLAPQALAQRQPL----------------------------------------
>UniRef50_C4RMS6(28-283:418) Argininosuccinate lyase n=1 Tax=Micromonospora sp. ATCC 39149 RepID=C4RMS6_9ACTO  E=6e-13 s/c=0.31 id=26% cov=37%
----------------------------------------------------------------------------------------------------------------------------------------DVQMARSRNDLDAGVFRMLLRDQLTGVLDRVLATGATALAAAERYAEVVITGYAHRRPAQPTTIGHALAGYAEALAGQAVAYADLIDALNISPLGSCAfAGTDLDIDP-------ARVAELLGFA-GLVTNSYEAVAGADHLVRV-GTLNArsLATG-ARLARTLtdwltwRW-----------VTTPGDFTQGSIMPQKRNPVVLE------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_UPI000038E105(85-359:438) argininosuccinate lyase n=1 Tax=Ferroplasma acidarmanus fer1 RepID=UPI000038E105  E=6e-13 s/c=0.28 id=29% cov=40%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IMPGYTHYRQGMPVT----FQTYVDFIKNimvyNFNNIDSILNELKELPLG---YGSGFGSMSD---ANFKEVAEYMGMKKQIKNPLFSFMLYSDNYIKVLSAINSFLIDISRIFQDM-IIFSGDEMKI--IELPAgYVTGSSLMPNKVNPDFLEI-----------------------FQGYAAKSISLMNLLYSgtinkttgyhrdFQILKDEVIPFmvELKCVlngfpelfSGIKFNKEASERIIGNSI---------------------------------------------------------------------
>UniRef50_A9WJB9(119-310:466) Adenylosuccinate lyase n=3 Tax=Chloroflexus RepID=A9WJB9_CHLAA   E=7e-13 s/c=0.41 id=27% cov=31%
------------------------------------------------------------------------------------------------------------------------------------------------------------------LLPALESLLERIRQLADEEAATPMLARTHGQPATPTTFGKEMNVF-------FMRLRRAINDMMAIKITG-----KLNGASGVFAAHHVALPQIDWLKFSRA--FVRSLDLepillttqiepHDTLAALCDALKRIGAILTDLSQDCwRYISDGylvqaARAG---------EVGSSTMPHKVNPIDFE------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_UPI000185BF09(96-425:476) adenylosuccinate lyase n=1 Tax=Corynebacterium amycolatum SK46 RepID=UPI000185BF09  E=8e-13 s/c=0.24 id=20% cov=60%
---------------------------------------------------------------------------------------------------------------------------------------EHIHKGMTSRDLTENVEQLQVLQSLKVVRDKAVAVAARTAEKASEYQSLVMAGRSHNVAAQATTLGKRFASAADEMLLGIERVEDLVSR-YPLRGIKGPMGTAqdmldlLDGDESALASLENEIAE--GLGFDRVFDSVGQVyprtldfDALSALVELGAGPASLATT-------IRLMAGNETVteGFKE-----GQVGSSAMPHKMNARSCERVHG--FQVIlrGYMTMISEYAGTQWNEGDVSCSVVRRVALPDAFFAMDGMfETFLTVLSEfgafpaMIDRELERYLPFLASTKILMAAVRAGMGREEAHEIIKEhAVATALDMRE--------------------------------------
>UniRef50_A8NWV8(122-385:443) Adenylosuccinate lyase, putative n=1 Tax=Brugia malayi RepID=A8NWV8_BRUMA  E=9e-13 s/c=0.30 id=23% cov=48%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AEKTKDIVTVGRTHYQTASLVTVGKRAAMWAQELLMVFTKLEHFRENMRFRGVKG-ATGTQDSFMALFhnDEAKVDKLDELImkSAGFASRFYISGQTYSRQQDCDLVNIFALLGAATKKICTDIRILQA-----FGEVFEPfeSEQVGSSAMPYKRNPIKSERVS----------------------------------------SLARKLMSAPQHIVEGLTVDKERIEYNVHADL-------PFLALEKAMMLLTEEGADRQDayekIREVTLAAK---ETQKRERVDLESIL---------------
>UniRef50_A7AM59(120-310:477) Adenylosuccinate lyase, putative n=3 Tax=Aconoidasida RepID=A7AM59_BABBO  E=1e-12 s/c=0.40 id=22% cov=39%
-----------------------------------------------------------------------------------------------------------------------------------------VHMFCTSEDINSPAYSMGIRDCIEKVIkPTILRIIETVATFATENAGKPMLSRTHGQPASPTTFGKEFAVYVHRLSRQYCKYLDQIDYMAKF---GGAVGN-FNAHKiAFPDKNWPDLAKDFVENTLHLSYQDYSTQieCHDYISEVSDHISRVNTILKDLCVDMWLYTS-----YDLIKLRGVQgeVGSSTMPHKINPI---------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D2Q9D5(165-478:484) PurB Adenylosuccinate lyase n=28 Tax=Actinobacteridae RepID=D2Q9D5_9BIFI  E=1e-12 s/c=0.25 id=24% cov=59%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------LAEKAEEYRDKAMLSLTHGQPATPTTLGKELAVYVYRLSRQLNKV-RNQEYLGKINGATGTFGAHLAACPDVDWVAVSRefVTNRMGLTWNPLTTQIE---SHDWQAELYGTISHTNRILHNLCVDV-WMyiSRGVFA-----QVPVKGAtGSSTMPHKVNPIRfenAEANLEISCSLL---DTLSATLVESRWQRDLTDSTtqrnIGSALGYSVLALNNLMGGLnsihpNDIAIQAeLDANWEVLGEPI-QTAMRACELAGLPGMDKPYEKVKE-LMRGHEISQDAVER-FIDEQSFDEataarlkALTPATYTGVASR----------
>UniRef50_A6G4E8(39-412:479) Adenylosuccinate lyase n=2 Tax=Bacteria RepID=A6G4E8_9DELT   E=3e-12 s/c=0.20 id=22% cov=45%
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AYTHFQPAQLTTVGKRACLWAQDLAFDLETLEQLVARLPMRGVKGTTgtqasflqLFTSHDDPNAAIRELDRRVCEAMGFDRSIAVSGQTYTRKIDTWV--VSALADVAGSAAKFASDMRLLAH-ER----ELEEPfgKKQIGSSAMAYKRNPMRSERINALARFV--HSLATSPRETHGnqWLERTLDDSANRRLVITEAFLATDAILNLVVDVTAGIVVNPAMLAKNMADEL---------------------------------------------------------------------
>UniRef50_Q23FJ3(143-351:488) Adenylosuccinate lyase family protein n=3 Tax=Oligohymenophorea RepID=Q23FJ3_TETTH  E=5e-12 s/c=0.36 id=22% cov=33%
------------------------------------------------------------------------------------------------------------------------------------------------------------------LLKTLEEVQTNLISMAENNSAVPMLSRTHGQVASPTTVGKELANFAYRANRQINQIKNAKFS-AKLN---GAVGN-FNAHifayPEFDwSSLSQEFIESLGLEFNPYSTQIEPHDSIAEFYNTLSLLNTIYIGFSRdMWNYISI-------GYFKQRSKKSEVGSSTMPHKVNPI---------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A1TFG6(111-433:491) Adenylosuccinate lyase n=71 Tax=Bacteria RepID=A1TFG6_MYCVP   E=6e-12 s/c=0.23 id=18% cov=60%
---------------------------------------------------------------------------------------------------------------------------------------EHVHKGMTSRDLTENVEQLQIRRSLELVHARGIAVVARLAERAALYRDLVMAGRSHNVAAQATTLGKRFASAAEELLVALQRVRELIDR-YPLRGIKGPMGTAqdmLDLFDGDTDRLADLERRVAGfLGFTDIFTSVGQVYPRSLDHDVVSALVQLGAGPSSMAHTIRLMAGHELVteGFA-----PGQVGSSAMPHKMNTRSCERVNglQVVLRGYAS-MTAELAGAQ-WNEGDVFCSVVRRVALPDAFFALDGQTETFLTVLDEFGAYPAVIQRELDRylpflatTRILIAAVRAGVGRETAHEVIKE------------------------------------------------
>UniRef50_Q480B6(143-308:456) Adenylosuccinate lyase n=32 Tax=Bacteria RepID=Q480B6_COLP3   E=2e-11 s/c=0.44 id=27% cov=33%
------------------------------------------------------------------------------------------------------------------------------------------------------------------LLPEMDNILAAMKALAIEYKTIPMMCRTHGQPASPSTLGKEMANVYVRLQRQREQI-ANVEMLGKIN---GAVGN-YNAHlsaypevdwHEYANEFVTSL----GLSFNAFTTQIEP---HDYIAELFDAIARFNTILIDFDRDI--WGYIAMGHFKQKTI-AGEIGSSTMPHKVNPIDFE------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C3XBD5(146-400:475) Adenylosuccinate lyase n=2 Tax=Oxalobacter formigenes RepID=C3XBD5_OXAFO  E=3e-11 s/c=0.29 id=23% cov=45%
-------------------------------------------------------------------------------------------------------------------------------------------------------------------LPALNAVIEQLRSIAHQNASLSMLARTHGQTASPTTLGKE-------IANIVSRLQRAAGKIAAVEIMGkmnGAVGN-YNAHfsaypdfdwENFSRNVVEN---SLGLTFNEYTIQIEP---HDYIAELFDAIARANTILIDLNRDI--WSYISLGYFKQIT-KAGEVGSSTMPHKVNPIDFENSE-------GN---LGMANALLKH-MSEKLPisrwqrdLTDSTVLRNIGMALGYTVLAYDSCLRGlnkLEVNAERITHDLED-----------------------------------------------------------------------
>UniRef50_C0QI65(119-449:464) PurB n=1 Tax=Desulfobacterium autotrophicum HRM2 RepID=C0QI65_DESAH   E=5e-11 s/c=0.22 id=20% cov=59%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------LETLLKALEETGLKHKSVPMMGRTHGQPATPTTVGKEFINFAWRIRHELFILQGATVQ-AKIN---GATGN-YNAHY-FVYPEIDWISageRFLGQSLGLEPLLFTTQINPNASLSfiLHSLVRSAAIII-----DFdRDMWGYISLGYFRQQLKAGETGSSTMPHKVNPIDFENSegNMGLAIAMMDHLAVKL--QKSRFQRDLSDSTVLRSLGSALGYYVIGVKN-ALKGMGKIAVDPSAMVRDLEANPELLaepfqTAMR-VFGEENPYERLKD-LTRGKRIgrREL---DGFVDglekvPEDFR--LRMKALSVPQYTG---------
>UniRef50_Q5ZXD1(128-308:456) Adenylosuccinate lyase n=291 Tax=cellular organisms RepID=PUR8_LEGPH  E=2e-10 s/c=0.39 id=23% cov=33%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------PTIAEIMGSITLLGKQHADVAMLSRTHGQPATPTTMGKELVNFVARLKRPQQQL---AEVLIPAKFNG-AVGN-YNAHvAAYPEvdwrKHCANFVTSLGLSFNAYTTQIEP---HDGIAEVSQIMVRINNILLDYTQDI--WSYISLGYFKQKTI-AEEVGSSTMPHKVNPIDFE------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_P44797(141-440:456) Adenylosuccinate lyase n=56 Tax=cellular organisms RepID=PUR8_HAEIN   E=5e-10 s/c=0.23 id=25% cov=55%
----------------------------------------------------------------------------------------------------------------------------------------------------------------EVILPEWQKLIDEITRLAEEYKTIPLLSRTHGQPASPSTVGKEMANVVYRLKRQFKQLQNA-EILGKIN---GAVGN-YNAHlsaypnidwHKFSEEFVTSL----GIQWNPYTTQIEphdyITEFFDAVVRFNTIIidfdrdlwGYIALNHFK-----------QRTIAGEI-------GSSTMPHKVNPIDFENSE-------GNLgLANAVMTHLGQklpisrWQRDLTDSTVLRNLGVGLgyCLIAYAS---TRKGISKLEVNQPHLLEELNQNWEVLaepiqTVMRRY-GIEKPYEKLKE-LTRGKRVTEQAMRE-FIDKLDIpqEEKLRLQKLT---------------
>UniRef50_D0WKE9(147-384:517) Adenylosuccinate lyase n=1 Tax=Actinomyces sp. oral taxon 848 str. F0332 RepID=D0WKE9_9ACTO  E=5e-10 s/c=0.29 id=23% cov=48%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------PAALKLHDALAELAHAHADLPMLSRTHGQTATPTTVGKEMAVFAHRLSRQLRRI-ASADYLGKINGATGTFGAHVAALPDVDwPALSRAFVEGLGLVWNPLTTQIEphdwQADLFSDVVHANRIAHNLATDMWTyISLDYfhQNLAAQGTT------------GSSTMPHKVNPIRfenAEANLEVSSALF---ETLAETLVTSRLQRDLTDSTTQRNIGVAFGHSLLALDNLV-RGLAGVDPNPQRLAEDLDAS----------------------------------------------------------------------
>UniRef50_UPI0001BC98E5(10-171:171) 3-carboxy-cis,cis-muconate cycloisomerase n=1 Tax=Pseudomonas syringae pv. tabaci ATCC 11528 RepID=UPI0001BC98E5  E=4e-09 s/c=0.40 id=26% cov=34%
-------------------DAYFMQPEMR--EIFSDEGR--------VQGMLDFEAALARAQARVGLIPPEVVADIELSCD-----ARLFDFDALAIAIGSAGNS---------AIPLVKALGKQIAARSA-EAERYVHMGATSQDVMDSGLILQLRRASVLLERDLTLLADAMAEQAQRHAGTPLAGRTWLQQATPVTLGMKIAG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C1H6L6(24-238:299) Argininosuccinate lyase n=1 Tax=Paracoccidioides brasiliensis Pb01 RepID=C1H6L6_PARBA  E=7e-09 s/c=0.30 id=23% cov=41%
--------------------------------------------------------AFARANVATGILTKDEFASIENGLKQVLEEWR-TNAFKIVP---GVDEDIH-TANER---RLGEIIGKEIAGK--------LHTGRSRNDQVATDLRLWLRDELRVVETYLVDLLKVIAERAESDIEYVMPGYTHLQR------GQAFDG--------------------------------------------------------LIHNSMSAVGDRDFILETMQWGSTLMLHISRWSEDLIIYST---TEFGFVRLsDAYTTGSSLMPQKKNSV---------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_UPI000187E7E3(3-200:282) hypothetical protein MPER_06834 n=1 Tax=Moniliophthora perniciosa FA553 RepID=UPI000187E7E3  E=1e-08 s/c=0.33 id=22% cov=33%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ARDGIAECVSFLSIIGGTLGKIALDLLLLSSSEFGEVQEPFVPHRGA-SSTMPQKRNSISSEVIL-ACSKLLRQHASTAQDAMVSDLER-ASGPwhLEWSCVPEAFCAASGALKQ-TEFVLDGLVVDTQRMLQNLDMSKGLIvgeaimMGLAPSLGRNAAHDVVYEA-----------------------------------------------
>UniRef50_O49514(209-335:467) Adenylosuccinate lyase - like protein n=2 Tax=cellular organisms RepID=O49514_ARATH  E=1e-08 s/c=0.51 id=31% cov=26%
------------------------------------------------------------------------------------------------------------------------------------------------------------------ILPTMDELIKSISLIAKNFAYVPMLSRTHGQPATPTTLGKEMANFAVRLSEERRYLSETKIKGKF----AGAVGN-YNAHiSAYSNIDWPHVSEefVTSLGLTFNPYVTQTTKA------------------------------------GEI-------GSSTMPHKVNPIDFE------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q89AM3(115-306:460) Adenylosuccinate lyase n=2 Tax=Enterobacteriaceae RepID=PUR8_BUCBP   E=3e-08 s/c=0.33 id=27% cov=30%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------IKKIALLHHNVPMLSRTHGQPATPSTIGKELINFAYRLERQLKQFKNI-EILGKIN------GSTGNYNAlHFSHSSVDwhKISQ----EFVTSLGLFWnpyttQIEPHDFISEFFSCLARVNTILINFNRDIwgyislQYFNQTPK--LDEI-------GSSVMPHKINPIDFE------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D2SFW6(96-407:441) 3-carboxy-cis,cis-muconate cycloisomerase n=1 Tax=Geodermatophilus obscurus DSM 43160 RepID=D2SFW6_9ACTO  E=1e-06 s/c=0.18 id=18% cov=60%
-----------------------------------------------------------------------------------------------------------------------------------------VHVGATSQDVLDTALLLMARNAVAAVDADLAAAADTTADLAHVHRDDVLAGRTLMQQALPTTFGLKAAGWLAGLDGARLRLAEVVASL-PVQYGG-AVGT-LAASGGAGVVVRAALAEELQLtstavpwftvRLPIADLAGALGAAAGVVATVAVDVVLLAQTEVAEVV----------------EVGEGRGGSSAMPHKRNPVAAISARACARRAPG-LVATLLSAMEQEHERAAGAWHSEWPTLTELLSTVGSAASWLAESLRGLRPDPPRMaataaaAAEGPLAGALAEALAPTLGkgaaHDAAAAAVREARDGGRPLAEVV------------------------------------
>UniRef50_Q6L1N6(134-341:420) Argininosuccinate lyase n=1 Tax=Picrophilus torridus RepID=Q6L1N6_PICTO  E=6e-06 s/c=0.26 id=27% cov=27%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PGYTHYRQAMPMSVNTYINYIKSIFYHHFNNLDSFLMDLREMPLG---YGSGYGS---FSPVDFNQVSNLLNME-KNIKNPVYSslryIKNIENIVYL---ISSLAVDISRICQDIIIYSE------NDIITipPEYTTGSSLMPNKINP----------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6LYC0(13-479:486) Fumarate lyase n=4 Tax=Clostridiales RepID=A6LYC0_CLOB8   E=1e-157 s/c=1.19 id=48% cov=98%
---NFRKENDSIGSKDIPEDVYYGVQSLRAAENFRITG--LFMHPEIINSLAYIKKAAAITNCEVGVLDKKIADAIVKACDEILR-GNLHEYFIVDPIQGGAGTSLNMNANEVIANRAIEILGGKKGEYSIVHPNDHVNCGQSTNDVIPTAGKITALKLLEHAQSELYRLHDAFSQKAIEFDHIIKMGRTQMQDAVPIRLGQEFKAYSVAIMRDVNRMEKAMDEMRVLNMGGTAIGTGVNADVKYLKRVVPNLSEITGMDLIQAFDLIDSTQNLDSFVAVSGAVKACAVTLSKIANDLRLMSSGPRTGFGEINLPAKQNGSSIMPGKVNPVIPEVVNQVAFNIIGNDTTITMAAEGGQLELNAFEPIIFYCLFQSIDTLTYAVQTFIDNCVKGITANEERCRDLVENSVGIITAICPHVGYSTAASLAKEAIKTGTSIRTLILEAGLLSEDELNEILDPFNMTEPGISGKKSI-----
>UniRef50_C9KQJ0(1-461:462) Aspartate ammonia-lyase n=1 Tax=Mitsuokella multacida DSM 20544 RepID=C9KQJ0_9FIRM  E=1e-141 s/c=1.10 id=45% cov=97%
----MRKEHDFIGELEVPDEVYYGVQTMRAIDNFHITGQTI--DPDFVQSIARVKKAAAMANMATGRLDKKIGEALIEAADEII-DGKLLDQFPVDPIQGGAGTSINMNMNEVLCNRALEIIGQPKGRYDIISPNNHANMAQSTNDSFPTSIKVCLSHKAKKLTAALDRLATELEKKSEEYKDVLKMGRTHLQDAVPITLGQEMGMYASAVRRGIRRIDHAIDEIHVMNMGGTAVGTGLNAEPAYIKKVAETLSEVTGEKYVTADNMIDATNNTDGFSDVSSAMKTTALVLIKMANDFRLMASGPRCGLNELKLPKRQPGSSIMPGKVNPVIAEVLDQACYQVIGNDLAVSMGVENGQFELNVMEPVMAFNMFNSMKYMTNAVNTFVDKLLIGLEPNREQCQKWLDNSVGVVTALLPHIGYENSAMLAKEAYNTGKPIRQVIMEKGLLSREKMEHILSPRQMTTPGIA----------
>UniRef50_C1F6I6(2-474:477) Aspartate ammonia-lyase n=1 Tax=Acidobacterium capsulatum ATCC 51196 RepID=C1F6I6_ACIC5  E=1e-141 s/c=1.07 id=44% cov=99%
---ELRKEKDSLGFVEVPANAYYGAQTARAVENYPISG--MRAHPQLIRAFGMVKQAAAEANQELGLVEAPRAEAIRKAAQEVM-DGKWNAEFVVDVFQAGAGVSFHMNTNEVIANRANEILGGKLGEYAQVHPNDHVNYGQSTNDVFPTGMRVATLLALETLYPVLDKLAATFEAKAKEFHDVMKSGRTHMQDAVPIRLGQEFAAYGLAIEKGKKFLTLAADSLRELGLGGSAVGTGINTHPDYRAKAVAALSRISGQKLTPAADMRWAMQSNACMADVSAALRGIALEVIRISNDLRLISSGPNTGYAEIYLPSLQPGSSIMPGKINPVMPELAAMVSFQVVGNDTAVAMAVQAGQLELNVMMPTMAYSVLQSITILANMLRQFNDRCVAGITANAERCAQYAQSTVSLATALNPYIGYAKAAEIVKESVATGQSIISIARSKGLLSEQEISEILDPVRMTEPQYPLDAAKERDKK
>UniRef50_P07346(8-471:478) Aspartate ammonia-lyase n=12 Tax=Proteobacteria RepID=ASPA_PSEFL   E=1e-141 s/c=1.09 id=58% cov=97%
-AASFRTEKDLLGVLEVPAQAYYGIQTLRAVNNFRLSGVPISHYPKLVVGLAMVKQAAADANRELGQLSERKHAAISEACARLIR-GDFHEEFVVDMIQGGAGTSTNMNANEVIANIALEAMGHQKGEYQYLHPNNDVNMAQSTNDAYPTAIRLGLLLGHDALLASLDSLIQAFAAKGAEFSHVLKMGRTQLQDAVPMTLGQEFRAFATTLGEDLARLKTLAPELLtEVNLGGTAIGTGINADPRYQALAVQRLATISGQPLVPAADLIEATSDMGAFVLFSGMLKRTAVKLSKICNDLRLLSSGPRTGINEINLPARQPGSSIMPGKVNPVIPEAVNQVAFQVIGNDLALTMAAEGGQLQLNVMEPLIAFKIFDSIRLLQRAMDMLREHCIVGITANEARCRELVEHSIGLVTALNPYIGYENATRIARIALESGRGVLELVREEGLLDDAMLDDILRPENMIAP-------------
>UniRef50_Q65DB2(7-474:475) L-aspartase n=5 Tax=Bacteria RepID=Q65DB2_BACLD   E=1e-139 s/c=1.06 id=48% cov=98%
----YRTEKDFLGEKKIPADVYYGIQTLRAAENFPITGYKIHE--EMIKALAVVKKAAALANMETKRLYKGLGDAIVQAADEILE-GKLHDQFIVDPIQGGAGTSMNMNANEVIGNRALELLGHNKGEYIHLSPNTHVNMSQSTNDVFPTAIHISTLKLLEKLLDTMEYMLDAFKKKARDFDHVIKMGRTHLQDAVPIRLGQEFEAYSRVIERDIKRIKQSRQHLYEVNMGATAVGTGLNADPRYIENVVKHLAEISGLPLVGADHLVDATQNTDAYTEVSAALKVCMMNMSKIANDLRLMASGPRAGLAEISLPARQPGSSIMPGKVNPVMAELINQIAFQVIGNDHTICLASEAGQLELNVMEPVLVFNLLQSISIMNNGFRSFTDHCVAGIEANEKRLKAYVEKSAGVITAVNPHLGYEAAARIAREAILTGQSVRDLCLQNDVLTEEELDLILNPYEMTKPGIAGAELLNR---
>UniRef50_A9WAB2(13-479:484) Fumarate lyase n=19 Tax=Bacteria RepID=A9WAB2_CHLAA   E=1e-136 s/c=1.04 id=45% cov=98%
MAEGYRIERDSLGEMQVPANALYGAQTQRAVLNFPVSG--MRPYPAFVWAQTMIKRAAAEVNRDLGLLDPQIANAIIQAAEEVLA-GQHADQFVVDPFQAGAGTSHNMNVNEVLANRANQILGYSLDDpKKPVSPNDHVNMAQSTNDTIPTAIRLGCLWRLPELIAAIDDLADALEQKAIEFDDVVKSGRTHLQDAVPVRLGQEFGAYAKAVRNDMERIVTAANRLRRLGIGGTATGTGLNAHPEYHSRMVAKLSELTGHELVSSGNLFESMQSMADPADFSASLRTLCITLGRIANDFRLLSSGPATGLDEIRLPAVQPGSSIMPGKVNPVLAEMLNMACYHVQGCDLTVALAAQAGQLELNVMMPIIAHNLFEMMHVLIGAINAFTTKCVVGITANREKAAGWLAKNAILVTALNPVIGYLNGAAVAKEAMATGKTIKEVVVEKGLLTAEQVDELLDVRKMTEGGIQG---------
>UniRef50_C4JP97(76-506:654) Fumarate hydratase n=16 Tax=Saccharomyceta RepID=C4JP97_UNCRE   E=1e-133 s/c=1.11 id=35% cov=89%
MASGTRTETDAFGEVQVPGDKYWGAQTQRSLGNFDINQPQDRMPPAIVRAFGILKGAAATVNMRYGL---------------------------------------------VISNRAIEILGGTMGSKKPVHPNDHVNMSASSNDTFPTVMHIAAVLETEEtLLPALKSLREALQKKVERFEKLIKIGRTHLQDATPLTLGQEFSGYVAQLDRNIDRIQNTLPDLRLLAQGGTAVGTGLNTFKGFDEAIAEEVTKMTGTEFKTSPNKFEVLAAHDAIVEASGSLNTLACSLFKIAQDIRYLGSGPRCGLGELILPENEPGSSIMPGKVNPTQCEALTMVCSQVMGNHVAATVGGMSGQFELNVFKPLMIRNLLHSIRILGDGMKSFEKNLVVGLEADEKRIGSLLHESLMLVTCLNPVIGYDMASKVAKNAHKKGLTLKQSAMELKALSEEDFDnsdeELLFPMDLISPDVAAQ--------
>UniRef50_D1BPM6(2-451:451) Fumarate lyase n=3 Tax=Veillonella RepID=D1BPM6_VEIPT   E=1e-130 s/c=1.04 id=39% cov=94%
-----RIEYDSMGPVEVDARRIYGPQTQRSFNNFKIGDHRI--PIEQIKALALVKKACALTNAKCGAVTEEKAKLIAQVVDEIV-DGKWDEEFPLTVFQTGSGTQTNMNVNEVIAHRAKQL-----DESNPLHPNDDVNRGQSTNDTFPTAMHICAYFEItKRVIPALDGLIESFEKLQKKGKGLQKVGRTHLQDATFIMVDQEISAFVDGLKTAKTMLVQNADHLLDVALGGTAVGTGVNTPKGYLDVMETVLPEVTGAPFRVKNNKFQGLALKDAFMMAHGALNTLATTLFKIANDVRFLGSGPRCGYGEWHLPENEPGSSIMPGKVNPTQCEALTMVCAQVFGHNTTMTLCAGSGAFQLNVYMPIMIYDFVESCRLLADAMNSFTTHCIDGVEFVPEKLNFFVEQSLMIATSLTPYIGYDKSAKVVKEAYKRGCSIKEIILEEKLMTEDEFAEAVRMK------------------
>UniRef50_Q8FQP8(7-472:473) Fumarate hydratase class II n=31 Tax=Bacteria RepID=FUMC_COREF   E=1e-128 s/c=0.99 id=41% cov=96%
--QEFRIEHDTMGEVKVPAQALWRAQTQRAVENFPISGRGLESAQ--IRAMGLLKAACAQVNKDSGALDAAKADAIIAAGKEI-ATGKHDAEFPIDVFQTGSGTSSNMNTNEVIASIA-------KANGTEVHPNDDVNMGQSSNDTFPTATHVAATEaAVNDLIPGLKVLHESLAKKANEWDSVVKSGRTHLMDAVPVTLGQEFGGYARQIQLGIERIEATLPRLGELAIGGTAVGTGINTSADFGGKVVAELVELTGvTQLQEAANHFEAQANRDALVEFSGAMRVVAVSLYKIANDIRLMGSGPLTGLGEIQLPDLQPGSSIMPGKVNPVLCETATQVSAQVIGNDAAVAFAGSQGQFELNVFIPVMARNVLESARLLANTARVFATRLVDGIVPNEEHMKQLAESSPSIVTPLNSAIGYEAAAKVAKAALAEGKTIRQTVIDMGFvdgekLTEEELDKRLDVLAMANTDRKQK--------
>UniRef50_A3Y7G3(1-470:473) Hypothetical aspartate ammonia-lyase n=2 Tax=Proteobacteria RepID=A3Y7G3_9GAMM  E=1e-127 s/c=0.98 id=40% cov=99%
----MRIEHDALGERQLEETLYYGIQTLRAKENFDISGKTISNIPSFVESIIQIKKAAAMANHKAQVLDENLCKAICQAADEMLANPD-PANFVVDIYHGGGGTSANMNINEVLANRANEIMTGHKG-YDQVHPNTHVNMGQSTNDVIPAAMKMAVFNSLNDLESVLTNFVISLQKKETEFNDVVKLGRTCFQDALPTTLGQQFSGYRNGFERMISELHDIKASCLELPLSATAVGTEFGTFPGYKSFLFSALEEVTQTRWTVEHNLFDGLQNADIWIKVSAIIKAIALNLNKLAGDLRLMSSGPRAGLGEITIPAVQPGSSIMPGKINPVMPEMAMQVYFRVLGNDLAITRACE-GELDLNVWESLILNCVSESCDLLGACMPLLASKCIDGIKANAEKCQQDAENSLALSTVIATLFDYQTASKLAKQADAEKKTIKQVVIESGILSPTEAERYLSPLTMTSPEKFNQLYSTKRR-
>UniRef50_Q30VF1(1-468:490) Aspartate ammonia-lyase, putative n=3 Tax=Deltaproteobacteria RepID=Q30VF1_DESDG  E=1e-124 s/c=0.95 id=39% cov=96%
----MRTEHDALGSRELPADALYGIHTLRAAENFPVSPYRL--APPLIRALAQVKLACARTNARLGYLDNRLAEAIETACLEII-GGSHQDSFITDPFQGGAGTSANMNMNEVVANRACQLLGGVPGQHSLVSPLNHVNMHQSTNDVFPTALRVAMLHELTALEKETAALQAQLQQLEAAHQDTLRLGRTQLQDAVPMTFGMTFGAWAEAVARDRWRVFKSRERIRQVSLGGTAIGTGLGAPRDYILKAADTLRSVTGLKLSRAENLVDATQNTDQLVEVSAILKALAANLLKISTDLRLLGSGPCAGLGELKLPAMQAGSTIMPGKVNPVIAEAVSQAALRVLANDGLAAHASAMGTLELNQFMPLLAHTLLESLHLMRSSVTLLNNRCMQGLEPQAEQAQSHVGRSAALAAVLVPLAGHTAVEQMLHTARTTGTPFARVAAQALCVPEDNIRSLLAPERMRKLGF-----------
>UniRef50_D2RIU2(5-431:472) Argininosuccinate lyase n=4 Tax=Bacteria RepID=D2RIU2_ACIFE   E=1e-87 s/c=0.76 id=21% cov=79%
---------------------------------------------------GSIAHAHMLA--KVGIISQEDAAAIEKGLKEILAEIQAGKFDFSTQLE-----DIHMNIEAAL-------------TDKIGDAGARLHTARSRNDQVALDMHMYMKREVTEIMDLLIAFEEALLTMAEKHLKTLMPGYTHLQRAQPITFAHHMLAYFNMLRRDFRRLQGVWDGADIMPLGAGAVaGTTLPIDRF-------QVAEELHFS-QVYGNSMDAVSDRDYVLEFLSFASLLMMHLSRLSEEMCLWSST---EFGFIELdDAFATGSSMMPQKKNPDISELVRGKTGRVYGHLTALLTTLKGLPLAYNKDLQEDKEGFFDAIDTVKFSLQVYRDMILST-KVNKERMAEAVHKDYSNATDLADYLvrkgmpfrkAHAVVGKAVAKAIAEHKLLGQLTLEEykemSPLFEKDLLECLKPEN-----------------
>UniRef50_Q3A9W6(2-430:456) Argininosuccinate lyase n=4 Tax=Bacteria RepID=ARLY_CARHZ   E=2e-87 s/c=0.76 id=22% cov=66%
-----------------------------------------------------------------------------------------------------------------------------------------VHTGRSRNDQVALDTRLYVKKEGTAIIALIKELQETLINLAEGHLNTIMPGYTHLQRAQPVTLAHHLLAYFWMFDRDRSRFYDCLKRADRSPLGAGALaGTTLPLDREF-------VSELLGFNGV-CENSLDAVSDRDYILEFLFAAATTMMHLSRFSEEIVLWNSKEFS-FVEI-DDRYATGSSMMPQKKNPDAAELIRGKTGRVYGNLMAVLTMMKGLPLAYNKDMQEDKEPLFDTVDTLKGSLRVFT-GMLKTIKFNQGAMYKAALKGFLNATDLAEYLvekgvpfreAHRITGELVLKAEKTGRELLELSLDElkemSPLIEEDIYEKLKIENVL---------------
>UniRef50_A4XKG3(15-437:462) Argininosuccinate lyase n=4 Tax=Bacteria RepID=ARLY_CALS8   E=2e-84 s/c=0.75 id=21% cov=64%
-----------------------------------------------------------------------------------------------------------------------------------------VHTARSRNDQVVLDERLFCREKNLYLQELIKNLIDTIIKLAEENIDTIMPGFTHLQKAQPVLFSHYILAYAQMLKRDLLRFRQNFISINLNPLGSAALaGTTFDIDRFF-------VADQLEFDGVT-ENSIDTVSDRDFILEMLFNIAMLQMHLSRLAEDFIIFNTD---EFRFIELdDAFCSGSSIMPQKKNPDALELIRGKTGRTFGNLIGLLTVLKALPLSYNKDMQEDKEFLFDSIDTAEKSLII-VNEILKTLKVNKENMLLACKSGFINATDLADYLvtkgvAFRDAHfvvgNIVKYCIENNKSLEELSTEEFKRFCDKIEE-----------------------
>UniRef50_A9KQ51(2-428:462) Argininosuccinate lyase n=42 Tax=Bacteria RepID=ARLY_CLOPH   E=2e-83 s/c=0.73 id=20% cov=53%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNDQVALDMKLYTRDEITVLDELLRDLLFELYSLMKEHTETYMPGFTHLQKAQPITLSHHMSAYFEMFRRDRDRLSDIFKRMNTCPLGAGALaGTTYPLDRAYT-------ASLLSF-TEPTRNSMDSVSDRDYLIELLSALSTIMMHLSRFSEEIIIWNTNEYR-FVEI-DDAYSTGSSIMPQKKNPDIAELVRGKTGRVYGALMSLLTTMKGLPLAYNKDMQEDKELTFDAIDTV-KGCLSLFTGMIRTMKFNRDTMKA---------------------------------------------------------------------------
>UniRef50_B2A8E3(3-421:487) Argininosuccinate lyase n=1 Tax=Natranaerobius thermophilus JW/NM-WN-LF RepID=ARLY_NATTJ  E=4e-83 s/c=0.74 id=22% cov=56%
------------------------------------------------------------------------------------------------------------------------------------------HTARSRNDQVAVDMNMFLCDKAIKLVNELLQNMSVIKELSEQHTKTYMPGYTHLQRAQPTTLGHHMLNYFWKFQRDASRLIDFRNRADLSPLGSGAfAGTGFNISR-------RSTRKDLGF-TQQFENSMDAVSSRDLSLEFIFCLSSIMINLSRLAEELILWSTK---EFDFIELdDAFATGSSIMPQKKNPDVPELIRGKTGRVVGHLTALATTYKGLPMAYNKDFQEDKEGLFDSLDTVESSLK-LTSKILSTMTIKTKNMEKALYQDFSNATDIADYL-----------------------------------------------------------
>UniRef50_Q7MH73(2-429:624) Probable acetyltransferase n=32 Tax=Gammaproteobacteria RepID=ARLY_VIBVY  E=6e-83 s/c=0.72 id=22% cov=62%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNDQVATDLKLWCRQQGHQLLLGLDKLQTQMVNVAKQHQATVLPGYTHLQRAQPVTFAHWCLAYVEMFERDYSRLSDALTRLDTCPLGSGALaGTAYPIDR-------EQLAQDLGFR-RATRNSLDSVSDRDHVMELMSVASISMLHLSRLAEDMIFYNSGE-SGFIELA-DTVTSGSSLMPQKKNPDALELIRGKTGRVYGSLAGMMMTVKALPLAYNKDMQEDKEGLFDALDTWND-CMEMAALCFDGIKVNGERTLEAAKQGYANSTELADYLvakgipfreAHHIVGVAVVGAIAQGCALEELSLE----------------------------------
>UniRef50_Q9LEU8(51-485:517) Argininosuccinate lyase (AtArgH) n=20 Tax=cellular organisms RepID=Q9LEU8_ARATH  E=6e-81 s/c=0.70 id=23% cov=76%
-------------------------------------------------------KAHASMLAHQGLITDSDKDSILRGLDDIERQIEANKF----EWRTDR-EDVHMNIEAALTDLIGE-------------PAKKLHTARSRNDQVATDFRLWCRDAIDTIIVKIRNLQRALVELALKNEALIVPGYTHLQRAQPVLLPHVLLTFVEQLERDAGRYVDCRARLNFSPLGACALaGTGLPIDRFMT-------ANALGF-TEPMRNSIDAVSDRDFVLEFLYTNANTGIHLSRLGEEWVLWASE---EFGFMTpSDSVSTGSSIMPQKKNPDPMELVRGKSARVIGDLVTVLTLCKGLPLAYNRDFQEDKEPMFDSTKTIMGMIDVSAEFA-QNVTFNEDRIKKSLPAGHLDATTLADYLvkkgmpfrsSHDIVGKLVGVCVSKGCELQNLSLEE---------------------------------
>UniRef50_A2Q840(45-468:477) Contig An01c0080, complete genome n=14 Tax=cellular organisms RepID=A2Q840_ASPNC  E=1e-80 s/c=0.71 id=17% cov=80%
------------------------------------------------------EAALARAQSRCDVIPSQIGEMVTRKLRESkldMERLRYETEIVGYPILP---------------------LVRQLSAICGDEAGKYVHWGATTQDIMDLASVLQMKEGLDIVEHHLKKVISTLRGLSVKYKDTPMAGRTHLQHALPVTFGYKCAVWLSGFQRHLERLEQLKDRCLLVQFGGAAgsmasLGTG-----DDGLRVRKALAEELGLTDPPITWHV----ARDGIAEITNFLALMGGSMGKLALDIIIMSSNELGEVSEPFVPHRGA-SSTMPQKRNPISSEVILA-ASKILRSNAGLVLDGMVADFERASGPWHLEWVAIPESFVIAVGALSQTQFALSGLCVHSQKMLENLHSTKGLivaeavMMGLAPHVGRQQAHDTVYEAcresIEANQSLLECLMKKtevtSKMSEERLSQLYDPVNYLGASTR----------
>UniRef50_B6A0Z2(5-297:310) Aspartate ammonia-lyase n=1 Tax=Rhizobium leguminosarum bv. trifolii WSM2304 RepID=B6A0Z2_RHILW  E=2e-80 s/c=1.03 id=49% cov=59%
-----RIETDLIGPLPIPANALYGVHTRRAELNFNVSGMRLSDFPELIQSMAMVKKAAALTNHDLGLLNAEKCQAICEAADDLIELNEIEHNFPVDMMQGGAGTSTNMNVNEVLTNIALHKLGAYLGDYSTLHPNDDVNLSQSTNDVYPTALRLTILRACDALVSSQVELRDAFRAKSYEFRDALKIGRTQLQDAVPMTAGQEFEAFAELIDEDISQVYAVCRLLKEVNLGGSAIGTSINVPTGFTAIACGHLSKISGLQVIPARNLIEATSDTGGYVSFSGVLKRI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C9KN76(17-435:452) Adenylosuccinate lyase n=1 Tax=Mitsuokella multacida DSM 20544 RepID=C9KN76_9FIRM  E=3e-80 s/c=0.72 id=19% cov=81%
------------------------------------------------------EAALAQAQGELGVIPKEKADIIVKYAKADL----------IDIPSIGEGYKSSITIVPLL-NAFKKIL--------PEHAGEYVHWGATSQDIVDTGMVLLERDAYDIILRDAKACLKAILKLVKKYRDTPEAGRTHVVHAIPITFGYKAAVWADELGRQIERFEGMKKRV-FVGEMAGAVGT-LASQPEKGLETQQRMFEILGLEVPTIAWHV----ARDNQAEFASMLALLAGTLGRIAHEIFTLQRTEILELEEPFFM-GKVGSSTMPHKRNPAVLENVLALLRNVRGIAPTV-VESMVSENERDWGCFISEWEAIPRACELMATALHKTKYILENLIVYEKHMERNLFVQKGLMMSecvmmhLARKLGRLTSHHIVynacMEAYEKEIPLKDVLMKTKevedAFTEEEIDYMLNPHNYLGLA------------
>UniRef50_UPI0001C4209A(23-434:472) argininosuccinate lyase ArgH n=1 Tax=Methanobrevibacter ruminantium M1 RepID=UPI0001C4209A  E=1e-79 s/c=0.73 id=24% cov=76%
-----------------------------------------------------------------GIIDSEIADKILDALDKLSEEGFDALEFDHSV------EDVHMAVE----NYVTKLVGPEAGF---------MHTAKSRNDQVATDIRLLLRDRISEIQIAILEFIEGILELAKEHKETVMIGYTHLQHAQPITLAHHLMAHAQALKRDYQRLDDTYKRVNLNPLGSAAMATTsFPIDRELT-------TRLLGFD-DYLENSMDGVSSRDHIAEAVFDLTALCTTLSKICEELVLWSTYEFGIVS--MADEYSSTSSIMPQKKNPDVAEVARSKCAIVNGELMTILTILKAIPYTYNRDLQEITPHLWNACDVAYDTLKI-TNHMLLTVTFNTERCLELAGANFATATDLADIMVRERkipfrtahkiVGRIVNEAVAEGLNPSEidgayvdnVADELGFdklnLDDDLIHNALNP-------------------
>UniRef50_P74384(20-419:431) Adenylosuccinate lyase n=8 Tax=Bacteria RepID=PUR8_SYNY3   E=1e-78 s/c=0.74 id=19% cov=78%
-----------------------------------------------------VEIAVCEAQAELGYIPQAAVDEIKAKA-------KFDPQRVLEIEAE--------VRHDVIAFLtnVNEYVG---------DAGRYIHLGLTSSDVLDTALALQLVASLDLILEQLEKLIQAIRYQAQQHRYTVMVGRSHGIHAEPITFGFKLAGWLAEVLRNRDRLVRVAQSI-AVGKISGAVGTYANIDPKVEAIACQK----LGLEPDTASTQVI---SRDRHAEYVQQLALLAASLERFAVEIRNLQRTDVLEVEE-YFSKGQKGSSAMPHKRNPIRSERLTGMARLVRGHAVA-ALENVALWHERDISHSSVERVAFPDCCILTHFMLKETTDLVKNLLVYPENMKRNMNvyggvifSQKVLLALVEKGMNREDAYRVVQGSAhqawnTEGGNFEELVRADaqvtALLSAEEIDQCFDPQQ-----------------
>UniRef50_Q6L0V1(5-434:451) Adenylosuccinate lyase n=4 Tax=Thermoplasmatales RepID=Q6L0V1_PICTO   E=1e-77 s/c=0.68 id=19% cov=87%
-----------------PIDYRYG----------RDNVKYIFSEENRMRLMLRVEAALAQAEYEYNIISRDAFLDIKNAVD--------SNSVRIERVHEIESRIHHDTMALVEALTEQCSAGKNF-----------VHFGVTSNDIIDTATAMQIKSAVKIIKDDIKNLMKTLIKLIDENKDSVMVGRTHGQHASPITFGLKLSVYLDEMSRHLKRLTEAGDRIVAGKI-SGPVGTGASLGKD-SIEIQNRVCEILGIKSEIASSQIV---CRDRYIEYLSIINNIATSLEKFATEIRNLQRPEINEVSEYFDERSQVGSSSMPSKRNPIVSENISSLC-RFIRSLIIPEYEAAVIWHERDLANSALERFTIPYASVLIDYVLYNMNDVFSHLYINKEEMLRKARSdefimSESIVRALTlSGMPRQEAHEFVRkasmEAYKNNKSLKSSLISAGvlkYIDEKTLEAAMDPVKFTGQAVS----------
>UniRef50_P24058(8-447:468) Argininosuccinate lyase n=41 Tax=Eukaryota RepID=ARLY2_ANAPL   E=2e-76 s/c=0.66 id=21% cov=75%
--------------------------------------------------------AYAKALEKAGILTKTELEKILSGLEKISEEWS-KGVFVVKQSDEDIHTANERRLKELIGDIAGKL-----------------HTGRSRNDQVVTDLKLFMKNSLSIISTHLLQLIKTLVERAAIEIDVILPGYTHLQKAQPIRWSQFLLSHAVALTRDSERLGEVKKRINVLPLGSGALaGNPLDIDREM-------LRSELEFASISL-NSMDAISERDFVVEFLSFATLLMIHLSKMAEDLIIYST---SEFGFLTLsDAFSTGSSLMPQKKNPDSLELIRSKAGRVFGRLASILMVLKGLPSTYNKDLQEDKEAVFDVVDTLT-AVLQVATGVISTLQISKENMEKAL-TPEMLATDLALYLvrkgvpfrqAHTASGKAVHLAETKGITINKLSLED---------------------------------
>UniRef50_D1JDZ4(12-386:498) Argininosuccinate lyase n=1 Tax=uncultured archaeon RepID=D1JDZ4_9ARCH  E=2e-76 s/c=0.77 id=26% cov=53%
--------------------------------------------------------------------------------------------------------------------------------------------GRSRNDEVATCIRIALRDELLELMKEVNYLRRALIEKAAENVDTLIPGYTHLQHAQATTFAHQYLAHADALARDFSRLLNAYEHTNLCPLGAAAfASTGFPIDR-------AKTTKLLGFN-SILENSMDAVSSRDFIIESISCFSNLMTNLSRLAEEIILWST---SEFDFIRVPvEYVTGSSIMPQKRNPDYAELIRARAGTVYGCLMSVLSICKALPYSYNRDLQEVTPHLFKATEYTTASVLVMT-GMVKGLELKKDKLEK---------------------------------------------------------------------------
>UniRef50_P04424(43-412:464) Argininosuccinate lyase n=119 Tax=cellular organisms RepID=ARLY_HUMAN  E=9e-75 s/c=0.76 id=21% cov=56%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNDQVVTDLRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVALTRDSERLLEVRKRINVLPLGSGAIaGNPLGVDREL-------LRAELNFGAITL-NSMDATSERDFVAEFLFWASLCMTHLSRMAEDLILYCTK---EFSFVQLsDAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMS-AVLQVATGVISTLQIHQENMGQAL-SPDMLATDLA--------------------------------------------------------------
>UniRef50_Q024Z9(12-421:437) Adenylosuccinate lyase n=59 Tax=Bacteria RepID=Q024Z9_SOLUE   E=1e-71 s/c=0.67 id=20% cov=80%
-----------------------------------------------------VELAASEALAELGVVPAGAARLL-----------REHAGFDVARIHEIEKEVKH----DVIAF--TTAVAETMKARGHAEASRWFHYGLTSNDVVDTAQALCLQQASAILLKDLAGLREVLKRRALEFQHTVQIGRTHGVHAEPITFGLKLAIWYEEAGRNLARLSAAAEDVR-VGKTSGAVGTFGHIDPETEEMICARLN----LKPAPVASQVIQ---RDRHANFVAALALTTALCEKIALEVRHLQRTEVRE-AEEYFAKGQKGSSAMPHKRNPVTCEQICGLA-RVVRGNVTPALEDVALWHERDISHSSVERVILPDSTILTDYLLEKTTKLVDQLLVYPERMRRNLDLTRGLVfsgqllLDLaAAGMLREQAYRLVQshamRAWEEEGDFRAAIEADpdiaAVLTRDKIAEAFSLER-----------------
>UniRef50_D2BHS6(23-417:451) Adenylosuccinate lyase n=7 Tax=Bacteria RepID=D2BHS6_DEHSV   E=2e-71 s/c=0.69 id=18% cov=66%
-----------------------------------------------------------------------------------------------------------------------------------------IHMGMTSSDVMDTALSLQLVEASKILNNGVKDLINALAAKAMEYKYTVQVGRTHGVHAEPISFGLKLALWMEEMKRNRQRLAEATKAITVGKM-SGAVGTYATLSPEIEEIACKK----LGLSPASISNQVIQ---RDRHAQYMTTLAIIAGSLEKFATEIRALQKTECHE-AEEPFEKGQTGSSAMPHKKNPELCERICGIA-RIIRGYSVTAMENQPLWHERDISHSSTERVIMPDGCLLIDYALHIFTNVIKGLNVFPEQMEKNLNLTGGLVysqrvmlALINKGLSRQQAYKMVQRNAMrtwQGEDnfmnlLKADAEVMQHVTSAEIDELFDYK------------------
>UniRef50_B0SHK4(3-405:478) Argininosuccinate lyase n=6 Tax=Leptospira RepID=ARLY_LEPBA   E=3e-71 s/c=0.67 id=23% cov=67%
--------------------------------------------------------------RRIGILSESEQRKIETGLGQIkkeIDSGKF--EFKIE------NEDIHMS----IESRLTELLG---------DLGKKLHTGRSRNDQVSQDVRLYIKSEMHSILILVYDLLTVWLKKAEAHTKTIIPGYTHLQIAQPIRASHYFLSHFWANVRDFEDFYSAFERADELVLGSGALaGVNYETDREY-------LRKDLNLA-RMSENSMDAVSQRDHIFKFLFASSQFMVHASRFCEEIILYTSQ---EFSYFKLPDHlTTGSSIMPQKKNPDVAELIRGKAGRVIGNLTHLLVMLKGTPLSYNRDFQEDKIPLFDtvkQIKICTEGIR----DMVEGIQIFPENATRSLRNGFSTATDLA--------------------------------------------------------------
>UniRef50_Q6SPG4(2-407:498) AttA n=1 Tax=Photorhabdus temperata subsp. temperata RepID=Q6SPG4_PHOTE  E=7e-71 s/c=0.67 id=19% cov=84%
------------------AEKLWGGrfskEIDRSVLKYTLTTDIDSRLIRY-DIWGSMAHLAMLNNGE--IVSKEAAGKIFSALLKLYESNERGTLTLDPELE-----DVHLNIESlVIREIGSE-------------YGGRLHTARSRNDQVVTDTRMYLRVELLDIQKNLYSFVNTLLKLSDECTHKIAIGYTHLQPAQPISLAFWYSCYASMFLRDLARLESAFNVTNLNVLGACALaGTSFPIDREIT-------SKLLGFDRELM-HSLDATSSRDFVLQTASTFAILMSNFSRLAEEIVIWNSHEFGLLA--IDDTFATGSSIMPQKKNPVVAELVKGRVGRIYGVLMQLLTMVKGVTLGYNCDLQEDKPMLWDAIDIIKNTTSILHQH-IENSDYKSDRAEELCWKNFSTVTELANYLVREK-----------NLPFREAHHLTGLLTQKLSTEAMDMRN-----------------
>UniRef50_Q1M9E8(54-326:350) Putative fumarate lyase-family protein n=2 Tax=Rhizobium RepID=Q1M9E8_RHIL3  E=3e-70 s/c=0.98 id=45% cov=57%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VKVGRTQLQDAAPVTAGKEFEAFAEFIDEDIVQVHYASKLLKEINLCGSASGTAINVPSGFAQAVCDHLSQKSGYRLIPARNFIEATSDTGGFV--SFVLEGIAFNLTKICNDLRLLSSGPRGGLGEIRLPPVQAGSSIMPGKGNPFIPEMMNQISFQVIGNDLTVTLAASAGQLQLNAMEPVIVLNILQSMRMLTRGMVILMERCIDGIEVDVDRCQALLDQSIVLAKPLAKLIGYSKAADLTKKALVEKRNLRDVVEEERGLTESQVHQI----------------------
>UniRef50_Q5SI61(12-424:436) Adenylosuccinate lyase n=4 Tax=Bacteria RepID=Q5SI61_THET8   E=2e-69 s/c=0.64 id=18% cov=66%
----------------------------------------------------------------------------------------------------------------------------------------YLHLGLTSSDIVDTAQNALLVEALGLVLEELKGVEEALKALALRHKHTPAIARTHGVHAEPTSFGLRFLSFLAAFQRDEERLKRARETIGVAMLSGS-VGNYAHVPPE----VEAHVASRLGLRPEPLSTQVVP---RDRHAEVMAALAILGGNIERVAVELRHLQRTEVLEAQE-PFHEGQTGSSSMPHKKNPVGLENLTGVA-RLLRGYLFPALEDIALWHERDISHSSVERVILPDATTLAHYALRRLKGILEGLEVFEENLARNLDLTRGLVysqqvlnALIARGLSRNKAYALVQrnalRSWKEGKSFLELLEADpeNPLKGKELRALFDPK------------------
>UniRef50_A8TRW1(21-428:444) Fumarate lyase n=1 Tax=alpha proteobacterium BAL199 RepID=A8TRW1_9PROT  E=2e-69 s/c=0.65 id=17% cov=76%
-----------------------------------------------VRAMAQVEASLARAEAKLGIVPQAAAERITEAT----------EGFVPDLEALGEGSEQ--------AGVAVIAFVQQFRVHVGGDAAQWVHFGATSQDIVDTALILQLRDALELISKRLDRVIAALATLADTHRNTVMAARTRYQQALPTSFGLKCAGWLMPLVRCRQRLTELRPRLLMVQFGGAA-GT-LAALGDKGIAVMEGMAADLDLACPPTPWH----TQRDGITEFGSWLSLVTGALGKLGQDAVLMAQTEVGELDESAGGGRGGS-STMPQKTNPVTGEALVA-AARLNATLLGNLHQGQIQEHERGGVGWQMEWATLPTMVVTSGAALAKTEALLGRLAVGIERMRANLgpENGLILAEaatfALAEYMPRPDAQALVKQAAR---------------------------------------------
>UniRef50_Q2ITS2(46-440:458) Adenylosuccinate lyase n=164 Tax=Bacteria RepID=Q2ITS2_RHOP2   E=7e-68 s/c=0.66 id=16% cov=65%
-----------------------------------------------------------------------------------------------------------------------------------------VHQGMTSSDVLDTCFNVQLVRASDILLADLDKVLAALKTRAFEHKMTPSIGRSHGIHAEPVTFGLKMAYAYAEFSRARDRLVAARKEVATCAISGS-VGTFAHIDP----RVEEHVAKAMGLAVEPVSTQVIP---RDRHAMYFATLGVIASSVERLATELRHLQRTEVLE-AEEYFSEGQKGSSSMPHKRNPVLTENLTGLA-RMVRAYAMPAMENVVLWHERDISHSSAERMIAPDSTVTLDFALNRLAGVIEKLVVYPDNMAKNLDRlgglihSQRLLTALTqKGCSREESYKLVQRNAMpvwrgEG-DFLTLLKKDpdmkKYMSDAEIEEQFD--------------------
>UniRef50_Q1ER98(45-425:510) Argininosuccinate lyase n=1 Tax=uncultured crenarchaeote 31-F-01 RepID=Q1ER98_9CREN  E=1e-67 s/c=0.68 id=21% cov=64%
------------------------------------------------------------------------------------------------------------------------------------------HTARSRNDQVTLDLRMKVRDDITAIEYAILEVVDALLARAKECIDAVMPMYTHLQHAQIGSFSHYLLAYVDMLLRDVDRLESCYARVNLSPLGSSAIgGTSLQVNRD-------RVANLLGFNGI-VENSIDATSSRDFLLEFCSCLCITMLDLSRMAEDMVLWSS---SEFNYIELsDELASTSSVMPQKKNPCPLELMRARASTVLGLLASIMGIVRSLPSGYSRDLQESKRIAFDVFKIVYESLLIMRQ-VVSGIIVKRKDMLNAAEKSYAIAVDVAEELvkrrgiafrvAHRLVGAIVAYANSHDKNLRD-------LSMDDLKAALDPFR-----------------
>UniRef50_A8M7B1(47-465:471) Fumarate lyase n=1 Tax=Salinispora arenicola CNS-205 RepID=A8M7B1_SALAI  E=2e-67 s/c=0.62 id=18% cov=81%
-----------------------------------------------------IEAALAQAQGELGMIPARAVAGIVSAAR--------LECIDLDAVQAEIDRSGHSLVG----------LLRVLQVACPDDTGEYIHFGATTQDIQDTGQALEMRDTLDELTREIAAILASLVELAEQHAGTVAVGRTHARAALPMSFGLKVASWIDELLRHTERLATARSRVVVAQLFGGAG--TMAGFGGGGVVLLERFAARLGLAVPTLGWHV----ARDRVVEFVTTLAMVSGTLGRVADEIRTIGRPEFGEVTE-PWRYGKVGSSTMPHKRNPERCEQVVVMA-KLAAAQAGIAFTAMVGDHERDARALRVEWACVPDVSHYTLAACEIVRELVTGLTVHEDRLRVNAQEvadqlaTERLMLALGRQLGKQTAHERVYElsqtAHDTGRPLRhlfdDCADLRDLVDERELDVIFDPSQYLG--------------
>UniRef50_Q9I6Q8(3-448:459) 3-carboxy-cis,cis-muconate cycloisomerase n=42 Tax=Proteobacteria RepID=PCAB_PSEAE  E=3e-67 s/c=0.58 id=22% cov=90%
---------------DVPAnqlfDAYFMAAPMRAV----------FSDRGRLQGMLDFEAALARAEARTGVVPATAVAPIEAACRAELYDPLALAEAV-----ATAGNS---------AIPLVKALGRQVAAGDA-EAERYVHLGATSQDAMDSGLVLQLRRALALLEQDLQRLAEVLADQAERHADTPLAGRTWLQHATPVTLGMKLAGLLGALTRHRQRLRELRPRLLVLQFGG-ASGT-LAALGEQALPVAAALAEELGLALPEQPWH----TQRDRLVEFASVLGLVAGSLGKFGRDVSLLMQTEAGEVFEPA-GAGRGGSSTMPHKRNPVSSAVLIAAATRAPG-LVSTLFAAMPQEHERSLGLWHAEWETLPELCCLVAGALQQAIGLLEGLEVDAQRMRRNLGLTHGLVLaeavsiALARRIGREAAHHLVeqccRRAVEQRRELRAVLGEEARVSAElsgdELDRLLDPAHYLGQARAwVERALAE---
>UniRef50_D2TK81(16-432:454) 3-carboxy-cis,cis-muconate cycloisomerase n=1 Tax=Citrobacter rodentium ICC168 RepID=D2TK81_CITRO  E=1e-64 s/c=0.60 id=19% cov=83%
------------------------------------------------QGMLDFEAALARAQAACGVIPASAVAPISRACR--------AGRFDMVALAESAQAAGNLAIPMVRQLTALVRAEDPA-------AAGYVHWGATSQDAIDTGLVLQLRAALSDTQTQLRLVIDSFARQALRYQHTVMPGRTWMQQALPVTWGLKLAGTLDALLRWESRLEQLLPRSLVLQFGGAA-GT-LASLKQDALPVAERLAQELDLTLPDTPWH----TQRDRLLEVGAWYAGVGATLGKFAQDFALLMQTEVAEVSE-PVAAGRGGSSTMPHKRNPVSCAAILTAMQRTPG-LMATLYNCQLQQHERALGGWQAEWEVLPEIMMLVGHVMQETQRLVQDMQVFAQKMRENLAITNGLLMaesvtlALATFTGKQQAHHLIEnlchQAATSQRSLLSLLLQEPQVTahfdESQLTSLLDPAGAIGSA------------
>UniRef50_Q2RWH5(16-419:437) Adenylosuccinate lyase n=13 Tax=Bacteria RepID=Q2RWH5_RHORT   E=2e-64 s/c=0.62 id=16% cov=65%
-----------------------------------------------------------------------------------------------------------------------------------------IHQGMTSSDVLDTCLAVQLTQAADLLLEDIDALLAALRTRAFEHKMTVCMGRSHGIHAEPVTMGLKFAGFHAEFQRARTRLVAARGEIATCAI-SGAVGTFANIDP----RVEEHVAAKLGLLPEPLSTQVIP---RDRHAQFFAVLGVIASSVERAALEIRHLQRTEVREVEE-FFSKGQKGSSAMPHKRNPVLTENLTGLA-RMVRAYALPAMENVALWHERDISHSSVERMIGPDATVTLDFALARLTGVFTNLVIYPEAIDRTLNQMGGLVfsqrvlLALTqAGVSREEAYRIVQRNAMEvwngQGGLLDRLKADAavtdKLTPEALEELFD--------------------
>UniRef50_Q1L4A4(37-442:499) Iminodisuccinate carbon-nitrogen lyase n=1 Tax=Ralstonia sp. SLRS7 RepID=Q1L4A4_9RALS  E=1e-63 s/c=0.61 id=22% cov=68%
------------------------------------------------------------------------------------------------------------------------------------------HMARSRNDIAATIDRMRARSIVLDTIEALGRVRKVALQRASEFADAVMPGYTHLQPAQPITFGFYLSAVAETLGRDMDRLHAALPRIDAMPLGAGALaGTRFPIDRQVT-------ADGLGFG-SLVHNTLDAVASRDFAWEAMSAMAIIALTWGRVAQDFYVWSTPEFGLLSFP--DRVASTSSIMPQKKNPAVLEYLRGKSAHIVGLLTTSLMTVKGTHFTHTGDSSRESIRSFWECCEETARCLSLFELVVGSVEPKRLNMLRRVTLDFSVATDLADGLvadaglsfrdAHHVVGGLVRMALDAGQSAGELT--SAMLDRAAVDVIGR--AIDWPEDKLRQYLD----
>UniRef50_Q3KCB2(43-420:475) Argininosuccinate lyase 1 n=14 Tax=Bacteria RepID=ARLY1_PSEPF   E=5e-63 s/c=0.65 id=19% cov=63%
--------------------------------------------------------------------------------------------------------------------------------------------GRSRNDQTANDLRLFLRDHVRTLAVEVLALQTALVDQAEQHVESICPGFTHLQQAQPIVFAHHLLAHAQSMLRDVQRLMDWDARTSLSPLG------AAAMAGSAIARQPQQSAKEMGYAGV-CENSIDAVASRDHVAEFLFIASMLGINISRLAEEFCLWSSRQFRWVD--LDDAYATGSSIMPQKKNPDIAELARGKAGRLIGNLTGLLSTLKSLPLSYNRDLSEDKNGVLDSVDTLLLVLPAMA-GMVATMTVNVEELRRQAPLGFTLATEVADWLavrgvpfkeAHEITGALVQACEKHDLELWEA-------SPALLAEI-DPR------------------
>UniRef50_A0RGU8(43-453:508) Argininosuccinate lyase n=83 Tax=Bacillus RepID=A0RGU8_BACAH   E=3e-60 s/c=0.57 id=22% cov=65%
--------------------------------------------------------------------------------------------------------------------------------------------GRSRNDMGVTMYRMSLRRYVLRLMEHHLLLQESILQLATDHKGTIMPAYTHTQPAQPTTFGHYTLAIYDTMQRDLERMKKTYKLLNQSPMGAAALSTTS------FPIKRERVADLLGF-TNVIENSYDAVAGADYLLEVSSLLMVMMTNTSRWIHDFLLLATKEYDGIT-VARPYVQI-SSIMPQKRNPVSIEHARAITSSALGEAFTVFQMIHNTPFgDIVDTEDDLQPYLYKGIE---KAIRVFciLNAVIRTMKVEEDTLKRRSYKHAITITDFADVLtknygipfrhAHHAASVIANMSLEQKKELHELCfkgvniyLQEKFkiqLLEKEWEEIISPEAFIQ--------------
>UniRef50_D0LZ81(23-420:443) Adenylosuccinate lyase n=6 Tax=Bacteria RepID=D0LZ81_HALO1   E=3e-59 s/c=0.58 id=16% cov=65%
------------------------------------------------------------------------------------------------------------------------------------------HFGMTSSDVLDTALALTCRRALERVEAGIDGLRQALARRAREHAHTPVIGRSHGIHAEPITAGLVFARWHAELGRAQARVERARAAISVGKI-AGAVGVYGNIEPGIEAAALGA-------LGLAPETVATQVVARDRHAELLCALALLGTAIEQIAVGVRHWQRTELGE-AEEGFGAGQKGSSAMPHKKNPILSENLTGLA-RLLRAYAGAAFENVALWHERDISHSSVERVSLPDATILADFMLARCQRVIDNLVVHPERMRENLERTGSlycseavLLALVRAGLPRQRAYEMVQRcalaAHAGEGDFRQLLGADSdirdHLSENALDAAFD--------------------
>UniRef50_Q93JQ9(41-456:505) Argininosuccinate lyase n=1 Tax=Rhodococcus fascians RepID=ARLY_RHOFA  E=3e-57 s/c=0.54 id=18% cov=69%
------------------------------------------------------------------------------------------------------------------------------------------HTARSRNDQVQTDARMVTREWLLDASEELLMFVQDLLGCPESEREAVLPGYTHSQAAQPISVAFWKAAHAQALLRDASRLMDAWKRININPLGACALaGTTFALDRDYT-------SRLLGFD-APMVNALDATSTRDWTVEVAGAAASGAVNLSRMQEEIVTWSSNEYA-LAEVH-DSFATGSSIMPQKKNPVVAELARGKSGRAVGALVQLLVMEKSVGLGYSCDLQEDKPVYWGALDTYLDTIRLCRRQNLHTA-FDGARGRALCWDNFSTATEIANILvsrfdvpfrtAHRITGDLVNAALGGGHTLRNVAFTTTFLREEhdidisevDMKQICDPlhtlRSYISAGSTGPTRVSEQQE
>UniRef50_C7MPV5(32-459:462) 3-carboxy-cis,cis-muconate cycloisomerase n=2 Tax=Actinomycetales RepID=C7MPV5_SACVD  E=3e-56 s/c=0.52 id=18% cov=85%
------------------------------------------------RAMLDFEAALAAAQADAGLIDRLHAERIERACH-------HNGHDDYDIAELGRAARGAGNPAAPLVRAITERVEGAAARY--------VHWGATSQDVVDTAAMLVAARARMALLADVEACTETLAELADEHAATVQVARTLSQHALPTTFGLVAAGWLTSLDTAAERLQAVRLPVQF----GGAVGTLASLGESGVEVLAALAARLGLAEPALPWH-----TDRTPVAELAGALGGLAGAVSGVARSIVTLTQTDVGELREQG-PPGSGGSSTMPHKRNPVAAVSALACAKQAPG-LVADLLAAMEHENQRASGAWHAEWWPLIQLWRVCGSAVHWLRTSLDRLRVDAERMRQNLDRGGGVLlaeritTELAPVVGRLAAHDAVtsccHRALDEGVPLADVLVDDPLvgahLSRERIERLLDPADYLGAApvfvrRALEKYRRRKEE
>UniRef50_Q8TXN9(45-435:508) Argininosuccinate lyase n=1 Tax=Methanopyrus kandleri RepID=ARLY_METKA  E=6e-56 s/c=0.56 id=23% cov=65%
-------------------------------------------------------------------------------------------------------------------------------------------LGRSRNDQVATSVRMRLRERALDLSRELVGLGRALLDLAREHAEVPIAGYTHLKRAQPCTIGFWMSTYAAAVARSARGLLRV-PGMDECPLGCSAFpGSTVPVDRH-------REAALLGFR-KPARHCGEATALRGPILEFLGRLATAASELTRLAGDLIQLCSDEL-GVVEPP-DELSSTSSVMPHKKNPDALELVRAELTVVAGLKGLGDAVHGKLPMFYNRDLQVLNGLLWDSVNRFELCVRVLR-KVVEGLDVDEEAARGTVLGSHAAAVDLAELVAeragltFREAHKVVgrvsARLDREGVPmsperadrvVEELEREGVKLRVEEVREVLSLKR-----------------
>UniRef50_Q3IME1(29-429:490) Argininosuccinate lyase n=10 Tax=Halobacteriaceae RepID=ARLY_NATPD   E=8e-55 s/c=0.54 id=20% cov=60%
------------------------------------------------------------------------------------------------------------------------------------------HTARSRNDEVAACIRYRLREDVLAAVEATLEAREMLLDVAGDHTETVMPGFTHLQPAQPTTVAHYLHSYASALARDTERLLDAYGRINRSPLGAAAfAGTPFDIDR-------ERTAELLGFDGV-VRNSMDAASARDFLVETTAAAAGLATTLSGLAEDLVVFSKAGYVEL----DDAYASTSSIMPQKKNPDTMELVRATAGDTAAGLNALLTILKGLPRAYNRDLQRAHPHAFEALDAVTEATEV-AAGAVATADWKEPALSEAAGEGFSTATGVADLLAMEgvpfrTAHELVARAAEAG-------------------------------------------
>UniRef50_A8M4P0(27-466:488) Fumarate lyase n=2 Tax=Actinomycetales RepID=A8M4P0_SALAI   E=2e-54 s/c=0.49 id=19% cov=82%
-------------------------------------------------AMVEFEAALATAQARLGAVPDGTAAAIRAAgesgrldLVELARLGREAANPVVGFVKHLTG---------LVASTAPEAAG-------------HVHAGSTSQDVLDSAAMLVATRALCLVRDDLARIRTALTELARDHRGTAAVARTLTQHAVPTTFGTKAATWLTLICDAHERVNALLRQGLPVSMGGAA-GTLAAyhdhltaagvADDHPELRLATLVADELGLARPTLPWH----AARTPIADLAAVLNFVGGALGKFAADVLVLSRTEIAEVAEPAAVGRGQ-SSAMPQKRNPVLSVLVATAARQIPVYALVLGQSMVA-EDERSSGAWHAEWQPLRECLRLAAGASHTAAELAQGVVVATERIRVNLSLTGSslvaerLSVALGQELGRQRAKEAVTRAVRDtemGVPaadaLRHALNEAGLVDGrsaclDSLDELLDPEGYLGAAAP----------
>UniRef50_Q1AVN7(23-448:448) 3-carboxy-cis,cis-muconate cycloisomerase n=2 Tax=Actinobacteria (class) RepID=Q1AVN7_RUBXD  E=2e-54 s/c=0.51 id=20% cov=85%
------------------------------------------------RAMLEAEGALARAGARAGVVPPEAAEEISRRCRELELDPEEL------------GERGRAAGNPVPA-LVKELTAAVPGE-----AARHVHRGATSQDITDTAAMLISREALGLILRELDGVCAACARLAEEHRETLVAGRTLLQQALPTTFGLKAAGWLVAALEARRVLREARERGLAAQLGGAA-GT-LASLGERGTRVLREYARLLALPEPALPWH----AARFRVAELGGALALAAGTLHKVALDVILMAQTEVGEAAEPSGGGRGGS-STLPHKRNPILSVVASANARRVQ-DLARTLYGSLAQEHERAAGAWHAEWEALSGALALTGGAAAAVREALEGLEVRPGRMAENLAVTEGLILAEnvttlaAERLGRLEAHELVEAAcrrvAEGGGTLREEILAEPRlreaLSEEEIEGALDPARYLGAAdefvdRALEMYRREGQR
>UniRef50_C9Z894(28-484:484) Putative 3-carboxy-cis,cis-muconate cycloisomerase n=1 Tax=Streptomyces scabiei 87.22 RepID=C9Z894_STRSW  E=9e-52 s/c=0.45 id=19% cov=83%
---------------------------------------------AYLRALLDAEAALTRAQAALGLVPAAAGPAVTSAADAAAFDAR-----SLAERARGGG-------NPVIPLVAdlTEAVGDPYGPY--------VHRGATSQDIMDTATMLVAARTLDLILADLGRTESALAALAAAHRDTVMPGRTLTQHAVPTTFGLKAAGWRSLVLDARDRLAVVRASLPA--QLGGAAGTLAAFtvfrstdestdestdestdestdDGNAAGSGTENAAAGTGAENASTTHALVAAYArevglrepelpwhtlRTPVADLAGALAFAAGALGKVAADVLVLARTEIAEVAE----GSGGGSSAMPHKANPVRSTLIAAAARRAP-QLAAALYGALAAEDERPAGAWHAEWEPLRDLLRLAGGAARDAVDLARGLRVDADVMRAHLDLTHGlivserLAAELAPVLGRARAKELltraARRVHAEGRPLGELLSEEPELSglGLDLADLVDPRRYTGSAA-----------
>UniRef50_C3BDI7(40-464:502) Argininosuccinate lyase n=1 Tax=Bacillus mycoides Rock3-17 RepID=C3BDI7_BACMY  E=1e-49 s/c=0.47 id=18% cov=68%
------------------------------------------------------------------------------------------------------------------------------------------HMDRSRNDFQACAQLMFAREQVFLIIEDLFEFIDVVHHVSELTSSMLMPGYTHYQAAQIISPGFYLSAVTEQVIELLKNLLFIYNRINKSPLGSGAM-SGLELEWD-----RQNMAKMLGFD-NIQNHALISVASREWALRVAGELSTFSVFLSRFVTDLIQWGSG---EYGFIDLPDQLSGiSSAMPQKKNFTILERIRGKTSHISTYYLDLIMGQRNTAFTNLVEISKEANSNLITLFKTTRSILKIFTTVMENIEFKEERMKEICINeyfgGFALANCLTlhEGIPYREAQAIVgryivlvmdnqlKPSEVNYKLLEQVCQDQGYqinLSENLIRKAFDPqQNLIGKNTAGA--------
>UniRef50_A0K2D1(29-464:501) 3-carboxy-cis,cis-muconate cycloisomerase n=3 Tax=Arthrobacter RepID=A0K2D1_ARTS2  E=2e-49 s/c=0.46 id=17% cov=69%
-----------------------------------------------------------------------------------------------------------------------------------------VHASLTSQDVLDSALMLLARNAVTALMTDVRAITTALAVFAEQHADTLCVGRSLTQHSLPFTFGLKAAQWFHGLAAAARRLEAVelplQTGGAAGTLAAGTVLTKGSVDTPFD--LSGNLAAHLGLAVAPGPWH----TNRLAVTSLGDALAAVTDALGKIAGDVLFLSRPEVGELAEPRAAGRGV-SSAMPQKQNPVLSVLVRSAALQAPGQAAQLHLAAANFNDERPDGAWHSEWPAFRQLLRLALGAAGHLRELAEGLQVFPAAMRRNLELSGPLLlsegvsAAVAPLLeerdgrtGKQQLQDVVDRTLqappaEQSGTYRRLLREavpASALSDEQLEELLDPASYLGQAGEISRRI-----
>UniRef50_D1C6A6(16-422:456) Argininosuccinate lyase n=1 Tax=Sphaerobacter thermophilus DSM 20745 RepID=D1C6A6_SPHTD  E=2e-48 s/c=0.48 id=17% cov=67%
-------------------------------------------------------------------------------------------------------------------------------------PGKKIHTARSRNDQVIVDLRLFLKQEAPRVERAILDCADALLSLAERHRLTPMPGYTHMQRAMLSSVGVWAGAYLEALLDDLTLLDAALDLNDQCPLGSAAsYGVPFPIDRRY-------VSDLLGFRAPQRNVLYAQNARGKFEAAVVQALSQVMLDLSKLAQDILLFTT---AEFGFFTIGAeFTTGSSIMPQKKNLGAMEMLRAKGSVMLAYQQQIMTVLAGLPSGYNMDYQETKRPFIDALDLTARAARV-AALTVRNLEPNEQ----------ALLAACTPDL---FATDAAYELVAEGVPFRDAYRRVGtaLETVPPMDPHEQLAKRTHLGTAGDLGLEES--
>UniRef50_C7Z8U2(63-477:509) Putative uncharacterized protein n=1 Tax=Nectria haematococca mpVI 77-13-4 RepID=C7Z8U2_NECH7  E=5e-47 s/c=0.46 id=17% cov=65%
---------------------------------------------------------------------------------------------------------------------------------------------------------ILMREAMDLLLKKLAKVISNLSAFALKWKEEPTLAYTHLQAAQLITVGKRAAQWVQDLMFDLESMEQVRKDLKFRGAQVGTTGTQASFLEIFhgDSAKCDKLNDLLckKFDFPACYDVSTQTYTRKVDLVVANAVAGLGATAQKICGDIRHLAHWKEI---EEPFEKSQIGSSAMAYKRNPMRSERVYSLARELMSKPTNFANTLSDQWAERTLDDSAIRRIDIPEMFLLAEAILIGLDNISDGLVVYPKRINARVQEELpfmitetIIMRLVAQGASRQEAHEEIRvlsheagyEVKNEGKPNDLVArMKSKDFFKPiwgELDNMLKAELYTG--------------
>UniRef50_Q3JSA0(448-842:914) Argininosuccinate lyase domain protein n=28 Tax=pseudomallei group RepID=Q3JSA0_BURP1  E=2e-46 s/c=0.48 id=22% cov=55%
-----------------------------------------------------------------------------------------------------------------------------------------VHTARSRNDINACVAKLRAREWFDTCGGKLWRVRAAIVDKAQHTLDWPLPTYSQYQAAQPGSFGYYLWSVETALRRDQAALERLDEELAVCPLGAGAgAGTDFPIRPGVS-------AALLGFA-RSFDSALDAVASRDLVLHFLAAIAIASTTLSRLAHDLQLWT---MRETDFLALPdELSGGSSLMPQKKNPYLLEIVKGKLAHVAGALNAAVFASQRTPFSNSVeIGTEMLAPCADAVQAFGESC-DLLRLMVSGVTGDPAKMRAAAEAGLVSAT-----------------------------------------------------------------
>UniRef50_Q1GJ78(23-348:357) Fumarate lyase n=4 Tax=Bacteria RepID=Q1GJ78_SILST   E=2e-44 s/c=0.56 id=19% cov=40%
-----------------------------------------------------------------------------------------------------------------------------------------VHPGATSQDLIDTAQALALRAANEIYISRLTTLIDALRDLEETHGDNRLMGRTRMQAALPISAGHRISSWISPLVRHTSRLEILRPEVEALQFGG-PVGDGQRSQPH-AAAMADHMGKALGLRAPERCWHTE----RDSLVTYAGWLSALTGSLGKFGQDVCLMVQQGVDALAQ----AGGGSSSAMAHKQNPVTAEML----------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B6KC85(145-486:500) Adenylosuccinate lyase, putative n=8 Tax=Apicomplexa RepID=B6KC85_TOXGO  E=2e-43 s/c=0.52 id=19% cov=62%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------HLLPAVDDLAASLHMRAVEFAEVPMLSLTHGQPATPSTFGKEIANFEWRVKNAIKRVRDVEFRGKYN----GAVGCFNALVVADAKVAWPEVArdfvESLGLTYQPYSTQIEQ---HDWIAELCDALARLNSILLDFSRDMWLYISRD---VLKLRVVAGEVGSSTMPHKVNPIDFENAEGNLELANALLRFLSTKLPVSRMQRDLSDSTVLRNVGVAFGHCLVAYES-AKKGLDRVDVNSEKMLKELDENWAVlgepVQTLLRKRGVRNAYEKLKSATR-GQDIDKERMQDivetcsKDLLPEDLEILrsLTPATYTGLA------------
>UniRef50_C1DL35(68-474:532) L-aspartate-like protein n=1 Tax=Azotobacter vinelandii DJ RepID=C1DL35_AZOVD  E=2e-42 s/c=0.43 id=20% cov=59%
-----------------------------------------------------------------------------------------------------------------------------------------VHSGRSRQDILAT-YRLAtLRRQVLDYAAAMNATRQRLLDIAARNADTLVPAYTNGVQAMPITYAHYLLAYAASFDRDAQRIRELYARLNRSPMGSAVLANSA------WPLNRERLARLLGFDEVR-ENSLDssQVSSYDIPIEAVDIAANSAIRVGALIGDIHTQYHQIRPWL--LLDEGSTYTSSAMPQKRNPGLLMRVRESASDTVGLAEAVTLRAHNVTTGMTDYK-----FAFDSLGVFDAATDMFkgMDNVLDALTINAARAREELENEWTTSMELADtlqrahqvpfRIGHSFASLIVEEARNEG-------------------------------------------
>UniRef50_C8NQR2(93-346:368) 3-carboxy-cis,cis-muconate cycloisomerase n=4 Tax=Corynebacterium RepID=C8NQR2_COREF  E=2e-42 s/c=0.69 id=23% cov=38%
-----------------------------------------------------------------------------------------------------------------------------------------IHPGATSQDIIDTSLMLCLRDATGEIIADLGELAELLAELTRTHRDTPMMAHTLGQQAVPTTVGCITAGWLQAVLRSRAALQELRFEVSY----GGAAGTMTATHPH-GFAIQDELAAELGL----HNSGLVWHSDRIPVTTIAAALATAAGAVRKIAGDVIFLSASEISELRE----AQPGGSSAMPHKANP----------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B6R3I0(17-345:356) 3-carboxy-cis,cis-muconate cycloisomerase, putative n=1 Tax=Pseudovibrio sp. JE062 RepID=B6R3I0_9RHOB  E=5e-42 s/c=0.53 id=21% cov=39%
----------------------------------------------------------------------------------------------------------------------------------------------TSQDVMDTTLALTLKQVSQILASRLAAVIGALETLKSANAEHTLMGRTRMQVALPITAGDRIATWIAPLKRYQQKLEDIAKQVSVLQYGG-PVGTS-STQGEHAEAIASQMAAELDLG---VPNQSWHTQ-RDNLVDYANVLSMISGSLGKLGADVTLMAQQ---GVGEIRLTGGGN-SSAMAHKHNPINAELL----------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1BFI0(139-480:488) Adenylosuccinate lyase n=4 Tax=Actinomycetales RepID=D1BFI0_SANKS   E=1e-41 s/c=0.51 id=21% cov=54%
-------------------------------------------------------------------------------------------------------------------------------------------------------------------LPAATALVEQISEMAREHASVPMLSRTHGQPATPTTVGKELAVLAHRLRRQVRRVEGA-EYLGKLNGATGTYGAHLAAVPGTDwPAVSKAFVEGLGLTWNPLTTQIE---SHDWQSELYADIARFNRILHNLATDVWTYIS--LGFFKQIPVP-GATGSSTMPHKVNPIRFENAEANLEISCALLDTLSATLVTSRMQRDLTDSTTQRNIGPafghsllAIDNVRRGLKALAVNgdlLADDLDANWEVLGEAV-QSAMRAASVAGVEGMENPYERLKE------------------------------------------------
>UniRef50_Q83FF1(1-453:481) Adenylosuccinate lyase n=7 Tax=Actinobacteria (class) RepID=Q83FF1_TROWT  E=2e-41 s/c=0.38 id=19% cov=86%
MSED---EYDSLS----PLDGRYG-PAVRALRGF-------LSESALIRERIRVEIGWVFFLWR-------------KAVFGLAEPTKEDERFLSSIVHDAHKNiPRVKKIEERIQHdvKAVEIfLRERFTQQGLGNIVELLHFACTSEDINNLAYALNMKAALsEVILPSIDELIGHLEKMSQKYAGDAMLARTHGQPATPTTLGKELLVFVYRLKRQRKNLED----VQFLGKFSGATGTFSAhcvAAPNYPwQEWAKEFVNSFGLIYNPITTQIEP---HDWQCELLERVGHICRILHNLATDMWSYISFGYFQQGFISE---SVGSSTMPHKVNPIRFENAEANLEMACGIISCIVASLSTSRLQRDLSDSSVQRNIGVALGHSLVAIDNL-KRGLAGIRLNKNRLTEDLNNNWeVIAEAVQTTI---RAEILACKSNEANpyERLKDFTRNKK-ITKHTLDE-----------------------
>UniRef50_A2BJL5(104-409:465) Argininosuccinate lyase n=1 Tax=Hyperthermus butylicus DSM 5456 RepID=A2BJL5_HYPBU  E=7e-40 s/c=0.55 id=22% cov=64%
--------------------------------------------------------------------------------------------------------------------------------------------GRSRNDHVSAALRLYTINKIIDTLYWLLQARLRLIELAEKHRGAPVLFHTHQQPSQLATLDCLLLAWEEALASAYKLLYSVIGLVDRSPLGASAgAGTLAPIDP-------EELARLTGFSGVLG-NSLYATGSRLDVTAAALAATALLVEASRIAENLVLLSTP---YVSAVRIPESHVaTSSIMPHKRNPVTLEVLRARAARAAGLAAGLLAIQKGLPYGYNLDLQEANPLLYTILRDAAESSRILAD-LFSSMEFDLERLSKLAESYIAWGAELAELL-----------ALRTGMPLREAYREVAMkLRDGKISELFQKLGVTSPS------------
>UniRef50_C6HSD2(3-427:456) Adenylosuccinate lyase n=1 Tax=Ajellomyces capsulatus H143 RepID=C6HSD2_AJECH  E=8e-40 s/c=0.39 id=19% cov=75%
----------------------------------------------------------AEAEKELGV--EISDEAIAQMKANVLMT---DNCFKV------AAEEEKRRRHDVMAHV------YAFGQVAPA-AQGIIHLGATSCYCTDNSDLISIRDALDLVRPKLATVIHKLSQFAVEYKDMPTLGYTHYQPAQLITVGRRAAQWVQDLLMDLEDIERARNDLRFRGAQGTT-GTQASFMELFnkDRAKVDKLNEIicTKAGFPSCYPISTQTYSRKVDLRVANAISALGTTVQRITGDIRHLAAQKEM---EEPLRKIKLGR--LPWRINGILC---------------------AANWFERTLDDSAIRRITIPEMFLSADAILIAMDNVVSGLVVYPARIRKLpfmatenimmkmvsLGKSRQDAHEEIRVLSHQ-ASDVVK--NQGGKnDLIERMKKSKFLAPVagDLDQLLDPMNFIG--------------
>UniRef50_B0SV88(18-349:384) 3-carboxy-cis,cis-muconate cycloisomerase n=5 Tax=Alphaproteobacteria RepID=B0SV88_CAUSK  E=1e-39 s/c=0.50 id=20% cov=39%
------------------------------------------------------------------------------------------------------------------------------------------HKGATSQDLADTALMLQAKAGAALIRIETERLVTALTALTQAHATTPMLGRTLLQGALPITFGLKTAGWLQGVVGALARFETETAAI-QLQLGG-ATGSLAGLD-GKAIEIAERLAAILDLPAAVTPWH----ARREGLAGLASALAILTGAVGKIAGDIALLAQNEVAEAFEPRV-AGRGGSSAMAHKRNPTGC-------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C7R360(137-477:484) Adenylosuccinate lyase n=9 Tax=Actinobacteridae RepID=C7R360_JONDD   E=3e-39 s/c=0.48 id=20% cov=54%
-------------------------------------------------------------------------------------------------------------------------------------------------------------------LPAARALADQVAAMAHEHKSVPMLSRTHGQPATPTTLGKELAVLAHRLRRQITRIEH-DEYLGKLNGATGTFGAHSVALPDVEwPQVSRQFVEHLGLTWNPLTTQIE---SHDWQAELYSDVARYNRILHNLATDVWTYIS--LGFFTQIPVP-GATGSSTMPHKVNPIRFENAEANLEISCALLDVLASTLVTSRMQRDLTDSSSQRNIGSAFGHSLLAIdnvargldrLAVAESVLRGdLDANWEVLGEPI-QSVMRAAAVAGVDGMDNPYERLKE------------------------------------------------
>UniRef50_A1TFG6(40-433:491) Adenylosuccinate lyase n=71 Tax=Bacteria RepID=A1TFG6_MYCVP   E=3e-39 s/c=0.42 id=17% cov=61%
---------------------------------------------------------------------------------------------------------------------------------------EHVHKGMTSRDLTENVEQLQIRRSLELVHARGIAVVARLAERAALYRDLVMAGRSHNVAAQATTLGKRFASAAEELLVALQRVRELIDR-YPLRGIKGPMGTAqdmldlFDGDTDRLADLERRVAGFLGF--TDIFTSVGQVYPRSLDHDVVSALVQLGAGPSSMAHTIRLMAGHELVTEGFA---PGQVGSSAMPHKMNTRSCERVNGLQVVLRGYASMTAELAGAQWNEGDVFCSVVRRVALPDAFFALDGQTETFLTVLDEFGAYPAVIQRELDRylpflatTRILIAAVRAGVGRETAHEVIKE------------------------------------------------
>UniRef50_A7AM59(114-460:477) Adenylosuccinate lyase, putative n=3 Tax=Aconoidasida RepID=A7AM59_BABBO  E=4e-39 s/c=0.48 id=16% cov=62%
-----------------------------------------------------------------------------------------------------------------------------------------VHMFCTSEDINSPAYSMGIRDCIEKvIKPTILRIIETVATFATENAGKPMLSRTHGQPASPTTFGKEFAVYVHRLSRQYCKY---LDQIDYMAKFGGAVGNFNAHKIAFPDKNWPDLAKDfventLHLSYQDYSTQIE---CHDYISEVSDHISRVNTILKDLCVDMWLYTSYDLIKLRGVQ---GEVGSSTMPHKINPIDWENAEGNIGLANSLFHYFSTKLPNSRMQRDLSDSTVLRNVGVAFCHSYLAYLSIL-KAFSRISVNESRALEELDANWVVLSEpLQIHLrmtgdasGYEKMLSLTRTGCVSKETMKDII------------------------------------
>UniRef50_A9HXU4(107-411:469) 3-carboxy-cis,cis-muconate cycloisomerase n=3 Tax=Burkholderiales RepID=A9HXU4_BORPD  E=1e-38 s/c=0.53 id=19% cov=60%
--------------------------------------------------------------------------------------------------------------------------------------------GTTTQDAVDTAHAVLTKTALAALLDELQKLAAALRALAHAHAATPMMARSLLQPAQVTSFGFKCAQSAGALQRSASQLCTLAPHALCVQLGG-AVGNR-AAMGHRAAQVELVLAAELGL---WASGQSWHTQ-RDAWMRLAMEASVCAGSLSKLARDWSLMSQFEVGELAEA---PRGRTSSAMPHKRNSVHCMQAIALTQPVPG-LAASLLGAMTQAHERAMGEWQAELSVWAPLWRRVHGAAAALRLAADGLRVDAARMQSHIDAlyqvifSEACTDALAPITGREAAQQaiehLAPQALAQRQPL----------------------------------------
>UniRef50_P44797(107-451:456) Adenylosuccinate lyase n=56 Tax=cellular organisms RepID=PUR8_HAEIN   E=2e-38 s/c=0.47 id=18% cov=62%
------------------------------------------------------------------------------------------------------------------------------------------------------------------ILPEWQKLIDEITRLAEEYKTIPLLSRTHGQPASPSTVGKEMANVVYRLKRQFKQLQNAE----ILGKINGAVGNYNAHLSAYPNIDWHKFSEEfvtsLGIQWNPYTTQIEP---HDYITEFFDAVVRFNTIIIDFDRDL--WGYIALNHFKQRTI-AGEIGSSTMPHKVNPIDFENSEGNLGLANAVMTHLGQKLPISRWQRDLTDSTVLRNLGVGLGYCLIAYAS-TRKGISKLEVNQPHLLEELNQNWeVLAEPIQTVMrrygiekPYEKLKELTRGKRVTEQAMREFIDKLDIPQEEKLRlQKLTPATYIGAAVE----------
>UniRef50_A4EGL0(22-342:347) 3-carboxy-cis,cis-muconate cycloisomerase n=1 Tax=Roseobacter sp. CCS2 RepID=A4EGL0_9RHOB  E=4e-38 s/c=0.50 id=22% cov=39%
----------------------------------------------------------------------------------------------------------------------------------------HVHQGLTSQDVVDTSLILALVQVLSLLKERLGLLDQHLAEKQRAFGNRSITAFTRMQPAMETTVHEVIDRWRQPFAELIEDLSDLQNKVGVLQWGG-PIGARAHVQAD---ALGASFAQHLGLK----DPGRDWHTDRTVIVKVTQLLCRIATVTGKIGDDIVLFA---ITGSDHITFEGGQ--SSAMPHKNNPVKAEAL----------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A7IQF5(48-445:505) Fumarate lyase n=3 Tax=Xanthobacter autotrophicus Py2 RepID=A7IQF5_XANP2  E=9e-38 s/c=0.40 id=18% cov=54%
-----------------------------------------------------------------------------------------------------------------------------------------------------TAYHLLVRERLLALGTSLARLGRALAVTALTHADDVMPDYTYLQAAQPTSFGHYVLGFAAPVMRDLERLQSLYGRADLCPAGCG----SMNGSVAFQDR--AALAQRLGFSG-PLAHGRDAMWQADLAIEAMALSVAASVGLDRLAEDLMIFAT---AEFGLVRLSDRHSrASKILPQKRNPYALAFVRGLANRLIGVAAGVAASGRTPTGQMDNRMQSYG-AVPEALDACAKAADLMAE-VIGALTFDAARARALLADGACFASDLA--------------------------------------------------------------
>UniRef50_Q23FJ3(45-452:488) Adenylosuccinate lyase family protein n=3 Tax=Oligohymenophorea RepID=Q23FJ3_TETTH  E=2e-37 s/c=0.39 id=21% cov=33%
------------------------------------------------------------------------------------------------------------------------------------------------------------------LLKTLEEVQTNLISMAENNSAVPMLSRTHGQVASPTTVGKELANFAYRANRQINQIKNAKFSAKLN----GAVGNFNAhifAYPEFDWsSLSQEFIESLGLEFNPYSTQIEP---HDSIAEFYNTLSLLNTIYIGFSRDMWNYIS---IGYFKQRSKKSEVGSSTMPHKVNPI---------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q54J34(121-461:466) Adenylosuccinate lyase n=59 Tax=cellular organisms RepID=PUR8_DICDI   E=7e-37 s/c=0.46 id=19% cov=58%
-----------------------------------------------------------------------------------------------------------------------------------------IHFGLTSQDINNTAIPLSIVESVEKvLIPQLKQsILEPLRQFAQQWKSIPMLARTHGQPATPTTVGKELMVFIERLENQINHLEQSVPHTCK---FGGATGN-LNAHkvsyPAIDWVVfSEKFVKVLHpsLKRMRFTTQIE---HYDNVASLLDAFKRINTILIDLCRDIWTYIS---MEYFNQKLVKGEVGSSTMPHKVNPIDFENAEGNMGVANALYEHLSAKLPISRLQRDLTDSTV----LRSIGVpFSHSILSFksIQRGLSKLVLNEANIAKDLDANWAVVseaiqTILRRE-GFPKPYEALKE------------------------------------------------
>UniRef50_Q480B6(100-451:456) Adenylosuccinate lyase n=32 Tax=Bacteria RepID=Q480B6_COLP3   E=1e-36 s/c=0.44 id=19% cov=49%
------------------------------------------------------------------------------------------------------------------------------------------------------------------LLPEMDNILAAMKALAIEYKTIPMMCRTHGQPASPSTLGKEMANVYVRLQRQREQIAN----VEMLGKINGAVGNYNAHLSAYPEVDWHEYANEfvtsLGLSFNAFTTQIEP---HDYIAELFDAIARFNTILIDFDRDI--WGYIAMGHFKQKTI-AGEIGSSTMPHKVNPIDFENSEGNLGIANALFTHLSQKLPISRWQRDLTDSTVLRNLgvgFAHTMIAYGATL----KGISKLEVNEANLAAELDSN----------------------------------------------------------------------
>UniRef50_C3XBD5(24-475:475) Adenylosuccinate lyase n=2 Tax=Oxalobacter formigenes RepID=C3XBD5_OXAFO  E=2e-36 s/c=0.35 id=18% cov=48%
-------------------------------------------------------------------------------------------------------------------------------------------------------------------LPALNAVIEQLRSIAHQNASLSMLARTHGQTASPTTLGKEIANIVSRLQRAAGKIAA----VEIMGKMNGAVGNYNAHFSAYPDFDWENFSRnvvenSLGLTFNEYTIQIEP---HDYIAELFDAIARANTILIDLNRDI--WSYISLGYFKQIT-KAGEVGSSTMPHKVNPIDFENSEGNLGMANALLKHMSEKLPISRWQRDLTDSTVLRN----IGMALGYTVLAYDSCLRGlnkLEVNAERITHDLED-----------------------------------------------------------------------
>UniRef50_D0WKE9(82-460:517) Adenylosuccinate lyase n=1 Tax=Actinomyces sp. oral taxon 848 str. F0332 RepID=D0WKE9_9ACTO  E=9e-36 s/c=0.41 id=17% cov=62%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------PAALKLHDALAELAHAHADLPMLSRTHGQTATPTTVGKEMAVFAHRLSRQLRRIASA-DYLGKINGATGTFGAHVAALPDVDwPALSRAFVEGLGLVWNPLTTQIEP---HDWQADLFSDVVHANRIAHNLATDMWTYISLDY--FHQNLAAQGTTGSSTMPHKVNPIRFENAEANLEVSSALFETLAETLVTSRLQRDLTDSTTQRNIGVAFGHSLLALDNLVRG-LAGVDPNPQRLAEDLDASWevlgepiqqaMRAAGLggATGMGnpYERLKELTRGRKVTAEDMREAIASLGMPDDVAARlAALTPAGYTGLAAR----------
>UniRef50_Q89AM3(115-451:460) Adenylosuccinate lyase n=2 Tax=Enterobacteriaceae RepID=PUR8_BUCBP   E=3e-33 s/c=0.43 id=16% cov=46%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------IKKIALLHHNVPMLSRTHGQPATPSTIGKELINFAYRLERQLKQF----KNIEILGKINGSTGNYNALHFSHSsvdwHKISQEFVTSLGLFWNPYTTQIEP---HDFISEFFSCLARVNTILINFNRDIWGYISLQY----FNQTPKlDEIGSSVMPHKINPIDFENSEgnlGLSNAIISHLIEKLPISR---WQRDLSDSTVLRNVGTVIAYSIIAYDSIILG-LKKLKVNTSRLLQDLNH-----------------------------------------------------------------------
>UniRef50_Q6PPG9(1-193:232) Probable argininosuccinate lyase (Fragment) n=1 Tax=uncultured bacterium RepID=Q6PPG9_9BACT  E=2e-32 s/c=0.74 id=23% cov=33%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LMVHLSRLAQELILWSAPEY-GYVELS-DEHTTGSSIMPQKKNPDIAELIRGRSALAIGNLTGMLALLKGLPLTYNRDLQDDKPLLFATLDTVIPSV-TLMRQMLEKARWNTERMRAALQGDFSTATELADYLvrkgvpfreAHAIVGGIVRECLQQGIALEDLTLE----------------------------------
>UniRef50_UPI000038E105(102-358:438) argininosuccinate lyase n=1 Tax=Ferroplasma acidarmanus fer1 RepID=UPI000038E105  E=4e-30 s/c=0.53 id=26% cov=30%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IMPGYTHYRQGMPVTFQTYVDFIKNIMVYNFNNIDSILNELKELPLG---YGSGFGSMSD---ANFKEVAEYMGMKKQIKNPLFSFMLYSDNYIKVLSAINSFLIDISRIFQDMIIFSGDEM---KIIELPAGYvTGSSLMPNKVNPDFLE------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q7KWJ4(118-461:471) Adenylosuccinate lyase n=63 Tax=Haemosporida RepID=Q7KWJ4_PLAF7   E=1e-28 s/c=0.38 id=17% cov=61%
------------------------------------------------------------------------------------------------------------------------------------------------------------------IIPNIQNIIDKLKEFSFNYSDVSLLSKTHGQPASPTTFGKEMSNYYYRLYKHINKLKNIEIYVKFN----GAVGN-FNAHKVCDPNIdwIDNIKYFIETYFNLHFSLYCtQIQDHDYICEISDTLARLNYTLIDLSVDMWLYISSNVLKLKVIQ---KEIGSSTMPHKVNPIDFENAEGNLHLANSLFKLFSSKLPISRLQRDLSDSTVLRNLGSSFAYSLISYKSLLRG-LNKIDVDQNVMNEQLNQNWcTLAEPIQIIM---KKYNIADsyeqlKNFTRGKSIDKQCMyqfiqqNCSHLPKNAIDELMNltPHNYLG--------------
>UniRef50_D2EG45(2-461:469) Fumarate lyase n=2 Tax=Candidatus Parvarchaeum acidiphilum ARMAN-4 RepID=D2EG45_9EURY  E=1e-136 s/c=1.06 id=46% cov=96%
--ENYRIEKDYLGEVKVPYDAYWGVQTQRAMDNFPISG--LRPIKNYTYAIIRIKKAAALANSEAGLLDKKKAKAIIEACDEILK-GKYDDQFLVDVYQAGEGTSNNMNANEVIANIAIEKLKGKKGDYSIIHPNDDVNMGQSSNDVIPTAIKLAAIELSNKLIDSLKELQTAFYKKAKEFDKIIKSGRTHLMDAAPIRLGQEFGAWADLIKDSILRIQAAKNELKKINLGGTAVGTGINADSRYTKNAIAYLSKFINERLVQAKDLPEVTESPSDLFNLSSALSVLSTDLIKIANDLRLMNSGPITGLAEISLPAVQPGSSIMPGKVNPSVAEMVDMVSFRVLGDSHTIELATQAGQFELNVMEPIINYCLLHDLIILGNACKVFSEKAINGIKVNKEHIAEMVEKTPGIGLALNPYIGYEKAAEVVKEAIKTNKSIPQLVKEKKLLSEKDFKEVFDPFNLTWP-------------
>UniRef50_C8P032(7-467:468) Aspartate ammonia-lyase n=1 Tax=Erysipelothrix rhusiopathiae ATCC 19414 RepID=C8P032_ERYRH  E=1e-130 s/c=1.01 id=45% cov=97%
-NQNVRIEYDSLGSVKVPKDALYGAQTVRALQNFQITGRHVNDM--MYLALAQVKKACALANKSVGELDGPRCDAIVFACDEII-SGKYKEAFITDAIQGGAGTSMNMNVNEIIANRAAQILNRPIGVYDYIHPNDHVNRAQSTNDIIPTAGKLTVLNLGLLLVEEMIFLADTFHAKALEFSNIIKVGRTHLQDAVLISMGQVFHSYESVVRRDIQRLKQSLSEMQVINLGATAVGTGINSVEGYREHAVTHLSRITGKSFVSAEDLVDATKHVDGFANVHGSLKTFAVGLSRICNDIRMMASGPKVGFNEIFLPEKQPGSSIMPGKVNPVIPEVVNQVCFQVIGNDATVTLAAEAGQMELNVFEPVLFDNLFESLEILRHACATLRIHAIQDIKVNEHRIQDYVEHSLAMATALVKYLGYEKVSEITKQALKENKSLKTLVLEQGLMSEAEVDEALKPESMIHP-------------
>UniRef50_Q0BTB3(35-497:497) Fumarate hydratase n=4 Tax=Proteobacteria RepID=Q0BTB3_GRABC   E=1e-122 s/c=0.95 id=38% cov=97%
-----RQEFDSMGTVMVPANRYWGAQTQRSLKHFSIGNDKMPK--EVYHAYGYVKKAAAIVNTKAGRLADWRAKVIIQAAEETIA-GKLDDNFPLYVWQTGSGTQSNMNVNEVLSNRAIQLLGGTLGAQAPVHPNDHVNMGQSSNDTFPTAMHIATVLELDtVLLPQAEAFAASLEAKASQWMNVVKTGRTHLQDAVPLTVGQEWSGYAQQVRDAIANVVASKAGLYKLAAGGTAVGTGLNAPKGFGHDIAQTIAELTGKPFITAPNKFSAQGSLDAMVATSAALRGLAVALMKIANDIRWLASGPRCGLGELLLPQNEPGSSIMPGKVNPTQCEAMVMVCIQVIGEDNAVAFAGSQGNFELNAMRPIIINNVLHSARILGDMCEKMRVYSIEGTELNRARIDASVDQSLMLVTALSPVIGYDNAAHIAEAANADGSTLREAALKSGKVDEATFNRVVDPQKLVGEGVAGA--------
>UniRef50_B8DTH4(29-488:511) Aspartate ammonia-lyase n=12 Tax=Bifidobacterium RepID=B8DTH4_BIFA0   E=1e-119 s/c=0.94 id=44% cov=96%
-----RLEHDVIGTMEIPADVYWGIHTQRAMGNFTVTGIADGSHTALIRAYATVKRACAIANYQLGMLDARKAHHIEQACLEI-ENGALADQFPVDVLQGGAGTSLNMNMNEVIANRALELAGKPRGDYGYIHPNDDVNRSQSTNDTYPAACRLAILQGLKPLREATQRLREAFHMQADRHSNDIKIGRTQLQDAVPMTYGQEIHAWASFLATDLEAMNTLAKRLCVFNLGATAIGTGICADLRFRHTATTVLAEITDLPITAASDPVAAVTDTSSYIEASAVLKNLAVHLKKAADDLRLLNSGPRCGFGDLTVPPRQAGSSIMPGKINPVIPECVDQCCFTIFGMDVTVNWACAEGQLQLNAFDPLIIHEILTAMTIAINAMDMFRTKCVDGLRINVEQGRRDAEMSPSICAALNGKIGYEQAMSIAKEAVATGKSVREVAGERTDADRTELDSLLDIAAM----------------
>UniRef50_C7DHL7(2-459:459) Fumarate lyase n=1 Tax=Candidatus Micrarchaeum acidiphilum ARMAN-2 RepID=C7DHL7_9EURY  E=1e-118 s/c=0.93 id=42% cov=96%
---PYRTERDVLGKVKIDSSSYYGSETKRAIDNFPVSGITVS--PDFIHYYALIKKAAAKANLKSGKLSQERASAIIKAAEEVA-SGKFADQFPVDVFQAGAGTSTNMNLNEVIANRAIELLGGRKGDYKKVHPNDHVNMSQSTNDTYHAAMRVAANATMRRnLIPALKALAATFQKKAAEFRNVVKIGRTHLQDAVPITLGDEMSGYYGAIEYAIEGLEQSLAQLSELPLGGTAVGTGINISKDYKANVIRELSAITRIKFKPARHMYATMQQEYAELAASNAIKTAAITLGKIANDIRLLGSGPRAGLNELILPPVQPGSSIMPGKINPSMAEMLNMVCFEVYGNACTIEQACSGGQLELNVFMPIIAFDMLYSIKILSNAVNAFNSRCARGIKANTKAINANLERNLSLATALSPYIGYAKAADIAAKAYREGKTVKEVCLAEGIMPKQELDRILNPKNLV---------------
>UniRef50_C1FHH1(3-451:468) Aspartate ammonia-lyase n=6 Tax=cellular organisms RepID=C1FHH1_9CHLO  E=1e-115 s/c=0.93 id=48% cov=94%
----------------IPADALYGIATARAMDNYDISGVKVRDYPEFIRAFAHVKRACATANGRLGLLPGDVVDAIVAACDELIQSDRHHAHFAVDMVQGGAGTSTNMCANEIIANLAAIHLGEPVGDYSRVHPNDHVNMCQSTNDAYPSAAKLAVVFKHVAVTHALEDLIASLRKKAIEFEHVVKMGRTQLQDAVPMTLGQEFRSFASSLAADLTFMQRNVDQLYELNLGGTAIGTKICADASFAEASVAALSEQTRLPLRSPEDFIEASSSTSSFLLFSNILRRVAVKVSKICNDLRLLSSGPRCGFNEINLPAAAPGSSIMPGKINPVIPEVMNQVCFQVIGTDHTIASASEAAQLQLNVFEPIIIYNLLNNMNLMERGLNTLRTKCIDGITANPERCKELVDNSIGIVTALLPLLGYKKATAVAKEALETGRPVAEI--ASRFADPREVAEMLRPEAMTHP-------------
>UniRef50_A9BSS6(14-474:477) Fumarate lyase n=3 Tax=Proteobacteria RepID=A9BSS6_DELAS   E=1e-112 s/c=0.89 id=36% cov=96%
-----RIEHDAFGPVHIPADRLWGAQTQRALELFTIGEERF--PQGLYRAFGLQKLAAARANRRLGVLDDERGAA-IEAAAAELRDGLLDAHFPLTIWQTGSGTQTNMNANEVIANRANQMLGQPPGTRSPVHPNDHANASQSSNDSFPTVMHLATALELrDHLLPALEQLQQRLQERALAFAGVLKVARTHLMDAVPMTLGQSFETFAHQVGHGIHRLQATQPRLWSLAQGGTAAGTGLNAPSGFDRVFCEEIQALTGLAVTPNPCKFEGMAAHDALIEVSGALNVVAGSLAKMANDIRLLGSGPRCGLGELVFPDDGLSSSIMPGKRNPTVAEVVVQAAYQAMGHHLTVTLAGSAGHFELNVAKPVLIHHLLRAMLALGDASRVFAEKLVAGLQAHTERLEQQVSHSLLQATALNPVLGYDAVARITREAMARGIAPRQAAVALGLITAAEYDRLVDLRAMAG--------------
>UniRef50_B4H329(152-513:537) GL13348 n=4 Tax=cellular organisms RepID=B4H329_DROPE   E=1e-106 s/c=1.07 id=40% cov=76%
----FRMEKDTFGELKVPAEMLFGAQTMRSKINFPIGDIGERMPMPVIQAMGILKKACAEVNKDYG-LDGKISDAVSCACDDVISGKFYKrGHFPLVIWQTGSGTQTNMNTNEVISNAAIKAMGGELGSKKPVHPNDHVNKSQSSNDTFPAAIHISVgMELNERLIPSLTHLRDALKCKSEDFKDIIKIGRTHLMDAVPLTLGQEFSGYAQQLSYGLDRINGCLPRVYELALGGTAVGTGLNTHKGFAEKVSKRIADLTCLPFVKAPNFFEALGARDAMVEVHGVLNTIAVSLMKIANDIRLLGSGPRCGLGELMLPENEPGSSIMPGKVNPTQCESITMICAQVMGNQVAVSIGGATGHFELNVCK-----------------------------------------------------------------------------------------------------------------
>UniRef50_O27580(5-447:449) Adenylosuccinate lyase n=14 Tax=Euryarchaeota RepID=PUR8_METTH   E=1e-105 s/c=0.87 id=22% cov=90%
-----------------PVEFRYGTPEMRV----------IWEAENKLQKMLDVEAALAQAEGELGIIPAEAASEIVRKASTEFVTLERVNEIERDTKHDIAS------------------LVKALAEQCEGDAGEYVHFGATSNDIVDTSNSLLLRDSISVLRDKLTRVLEVLLALADENRDRVCIGRTHGQHALPTTYGMKFAIWADEIHRQLERLDACSERLC-VGMMTGAVGTTAALGEE-GLEVHERVSEILGLRPVLISNQVVQ---RDNHAEFIMVLANIATTLDKIALEIRNLQRTEIMEVGEKFDPEKQVGSSTMPHKMNPITAERICGIA-RVIRSYVVAALENNPLWHERDLTNSSSERIILPEACILTDYILKLTLDVLCNLVFYPENIKRNLEFTGGLIMAErlmaeltRRGMGRQTAYAAVRqcaiEASRTGRSLRDVVLERSeimdYLTVEDLEEIMNPETYIGSARRmVERVLEESQK
>UniRef50_C6DDR5(15-435:450) Fumarate lyase n=17 Tax=cellular organisms RepID=C6DDR5_PECCP   E=3e-91 s/c=0.80 id=21% cov=85%
----------------------FGTPEMRA----------IFDDRELIRKYVEVEIALANAQARCGVIPEDAAAEITASCNADTLDFELLRH---------ETEIVGYPILPLVHQI----------SKQAGHSGGYVHWGATTQDIMDTAVVLQIRDAFALIEADIDALRSILAGLAARYRNTPMAGRTHLQQALPITFGYKAAIWLDMFDRHAERLAQLRPRVLVGEF-AGAAGT-LASLGDKGLAVQKALMAELGLGVPTSTWHV----ARDGFAEAVNLLAVITGSLGKIGYDVMLMASNEFGELYEPFVKGRGA-SSTMPQKRNPISSELMLA-CAKGVRQQAGLMLDAMVQDLERATGPWHAEWIAIPESFILSAGALHQAKFMLNGLIVDEKMMLKNLNMTNGLivaeavMMGLAPYIGRQEAHDIVYDAcrivNEKGGTLADVLNAmpsvSSRLDPKLINDLTNPVNYLGSA------------
>UniRef50_B5YAL3(2-427:478) Argininosuccinate lyase n=1 Tax=Dictyoglomus thermophilum H-6-12 RepID=B5YAL3_DICT6  E=4e-90 s/c=0.78 id=22% cov=65%
-----------------------------------------------------------------------------------------------------------------------------------------IHTGRSRNDQVILDLRLYLREETCDIAELLINLRKVLLELSEKFISTPMPGYTHLQQAQPVTLSHYFLAYDAMFSRDLQRLEDIYKRVDVLPLGSGALaGSTIPLDREYT-------AELLNFS-KISDNSMDAVSDRDFVLEFLFFSALTYNHLSRLAEEIILWATK---EFSFVKLPeEYSTGSSMMPQKRNPDVAELTRGKCGKLIGNLVNMFTIMKGLPLSYNRDLQEDKPSLFSSIDELKIALRVW-IGFLPKIEFDTERMYKLSSEDFLFATDIAEYLvlkgvpfreAHKIVGEVVRFCEENNKKFRELSLEEwrgfSELFDRDIFDLLNPES-----------------
>UniRef50_Q1Q5N1(4-410:460) Strongly similar to argininosuccinate lyase argh n=1 Tax=Candidatus Kuenenia stuttgartiensis RepID=Q1Q5N1_9BACT  E=6e-89 s/c=0.81 id=23% cov=63%
-------------------------------------------------------------------------------------------------------------------------------------PAKKLHTARSRNDQVALDLRLWVREQILITSNYLTLVQQGLVKKGKEYFGAIMPGFTHMQHAQPILLSHYLLAYVEMFERDEKRLADCAKRLNESPLGACALaGTTLPTDPMIT-------AKLLNFG-SICQNSIDAVSDRDFCMEYVFALSLISMHLSRLCEEWIIWCND---EFSFIDIsDAYCTGSSIMPQKKNPDVLELIRGKCGRVYSHLTTLLTLFKGLPLSYNRDMQEDKVAVFDAAETV-HSMLNIFAELIANTRFNSERMKLACENGFSDATALAEYLvkldvpfrkAHEIVGNIVRECVRLNRKIKDLDLE----------------------------------
>UniRef50_B5IFZ5(5-435:446) Adenylosuccinate lyase n=2 Tax=Aciduliprofundum boonei T469 RepID=B5IFZ5_9EURY  E=7e-89 s/c=0.77 id=18% cov=86%
-----------------PLDYRYG----------RDEVKKIFSEESKLRYMLLVEYTLMKAHAHFGNIPEYCAKAAKEAMDKVE----------LERVKKIEKEIKHDVMAMVKAY-----------AEKCGECGKYVHLGATSNDIIDTATALQLKDLFRYIERDFELLENALAELAAKYKNTVMLGRTHGQAAVPITFGLKTAVFLAEILRHHERFEELKKRVLVGKMIG-AVGTGAAL-GDGALEIQEFVMKELGIGYEEASTQLVG---RDRYVELVSFFSSLATSLEKFATEIRNLQRSEIGEVMEKFDVEKQVGSSTMAQKRNPITAENICGLA-RIIRGFLTPMHESAILWHERDLTNSSAERFIIPHTSILIDDIMVKAANLFNNLEINEERMLENIRSNEE-VMAEAIIIflvkngwSRQDAHEKLRQVSMQPGKFRENLMKDNELRpilEGKIEELLNPKNYIGSA------------
>UniRef50_Q8E271(5-428:462) Argininosuccinate lyase n=16 Tax=Bacteria RepID=ARLY_STRA5   E=1e-87 s/c=0.77 id=22% cov=57%
--------------------------------------------------------------------------------------------------------------NEDIHMNIESLLTAEIGE-----VAGKLHTARSRNDQVATDMHLYLKDKLQEMMKKLLHLRTTLVNLAENHIYTVMPGYTHLQHAQPISFGHHLMAYYNMFTRDTERLEFNMKHTNLSPLGAAALaGTTFPIDRHMT-------TRLLDFE-KPYSNSLDAVSDRDFIIEFLSNASILMMHLSRFCEEIINWCS---YEYQFITLsDTFSTGSSIMPQKKNPDMAELIRGKTGRVYGNLFSLLTVMKSLPLAYNKDLQEDKEGMFDSVETVSIAIEIMA-NMLETMTVNE--------------------------------------------------------------------------------
>UniRef50_Q49YV3(13-418:431) Adenylosuccinate lyase n=82 Tax=Bacteria RepID=PUR8_STAS1   E=6e-85 s/c=0.78 id=19% cov=66%
-----------------------------------------------------------------------------------------------------------------------------------------VHYGLTSTDVVDTALSYVIKQANEIIKKDLERFIDVLAQKAKDYKYTLMMGRTHGVHAEPTTFGVKMALWYTEMKRNLERFKQVRKEIEVGKM-SGAVGTFANIPPE----IEAYVCEHLGLDAAPVST---QTLQRDRHAYYVATLALISTSMEKFAVEIRNLQKTETREVEE-AFAKGQKGSSAMPHKRNPIGSENITGIA-RVIRGYVTTAYENVPLWHERDISHSSAERIMLPDVTIALDYGLNRFTNIVERLTVFEDNMLANIDKTFGLIysqrvllALINKGLAREAAYDKVQpkamESWETKTPFRTLIEEDAtitdLLTKEDLDECFNPK------------------
>UniRef50_B8E0W0(11-418:435) Adenylosuccinate lyase n=1 Tax=Dictyoglomus turgidum DSM 6724 RepID=B8E0W0_DICTD  E=2e-84 s/c=0.77 id=22% cov=66%
---------------------------------------------------------------------------------------------------------------------------------------EYIHQGLTSSDVMDTAFSLQIIEALNLIEDDLKRLMEEIKKKAIQYKNLPMMGRTHGMHAEPITLGFKFLSWWSELKRDLERLRVAKENISFGKF-SGVVGTLAHLSP----KIEEEACKILGLKPEPVATQVIP---RDRHAEVIYALSMIASTCERIALEIRHLQKTEVGELEE-PFREKQKGSSAMPHKRNPVLSERICGLS-RVIRGYINSALENIPLWHERDISHSSVERVIFPDSTSLTDYILNLLIGIINNLRINEERIKENMSMNYriyysqNLLLALTEkGVLRDVAYGWVQEdafrAVEQKRDFMDIVLEDNrireYLSEEEIKQCFSPE------------------
>UniRef50_B4U5U1(12-421:433) Adenylosuccinate lyase n=2 Tax=Aquificaceae RepID=B4U5U1_HYDS0   E=5e-84 s/c=0.77 id=21% cov=69%
-------------------------------------------------------------------------------------------------------------------------IGEQLGEYS-----KYFHMGLTSSDILDTALSLVLKDAIDSIIIDIDIVLELLKEKAFRYKDSVMMGRTHGVHAEPISVGLKFASWYDELKRQKERLQVAKKDVLK-GKISGAVGTFSNVDPEVEKIALQK----LGLEPEPAPTQIV---HRDRHAYLMSVLSLIGSSLEKFATEIRHYQKTEVLEMEE-PFSESQRGSSAMPHKKNPIHAERICGLA-RVMRANMIAAFENIALWHERDISHSSAERIIIPDTFIGLDYMFGLFEYILKGLKVNTDRMLKNMDISKGlyfsskvLVYLMQKGVDRDSAYDIVKRCAMrswdEEIMFKDALLEDkeasKYLTKEDLDKIMDPYEFI---------------
>UniRef50_D1SZ88(8-443:453) Adenylosuccinate lyase n=1 Tax=Acidovorax avenae subsp. avenae ATCC 19860 RepID=D1SZ88_9BURK  E=2e-82 s/c=0.71 id=18% cov=81%
-----------------------------------------------------VEAALASAQADMGIIPRDAAREIADKARvRHIDIGRMSADI------------------RRIRHSLVPAL-RQLQAACSADHGEWIHYGATTQDVIDTGVALQLKEFHAVALRDMRAVGRELARLAVEHRDTLMAGRTHGVQALPITFGHKCAVWLDELGRHHERLVQAAPRV-LVGMLAGAVGSQAAFGPN-AAELEERVLRRLGLGVPPISWA----PARDRFAEYANLLALIGGTLSKIGNELFNMQRDECDEVEE-GFPEGKLGSSTMPHKRNPVSAENLAGLS-RPLRYSAAMMVEGMVQESERDGIAWKVEWKALPEACMIAGAMLFQARHLLAGLKVNAAAMAANLGRmhgyllSERVMLELSARVGKQTAHEWIYEASMHGIThklgFAEAMRHHEslgrLLTEDEIHDLTDPAGYLG--------------
>UniRef50_A6V1S9(23-438:477) Probable lyase n=7 Tax=Pseudomonas aeruginosa RepID=A6V1S9_PSEA7   E=1e-81 s/c=0.74 id=17% cov=81%
-----------------------------------------------------VERALAATQAELGLIPHEAAQEIARVAR--------VERFDLAALGRESLETGHLLVPTIRA----------LARACEGGRGEYVHYGVTTQDILDTGLILQVKEAWGHALGLLHSIRGHLLALALRHRHTPMVARTHGQQALPTTFGYKVAVWVDEIDRHLARFDEARERVLVGNL-TGAVGT-LAAFGAQGFEIQRRTLARLGLGAPLTSWH----SARDRVLEAAWLLVQVSLTLGRVATEVYHLQRSEIDELREPARP-GQVGSSTMPHKQNPSTVDLISALS-RLVRSQMVALTDAAFQLHERDGTTWRIEWAALPELFVYAGALLTRMEALLaEGLEVREERMRANLDllggliLSERVMLALAGQFGKQSAHELLHEvslaSARQGVPFREALLAHPRLrgcfPAQTLEALLDPLGYVGLAA-----------
>UniRef50_B7LRV7(18-450:451) 3-carboxy-cis,cis-muconate cycloisomerase (3-carboxymuconate lactonizing enzyme) (CMLE) n=2 Tax=Gammaproteobacteria RepID=B7LRV7_ESCF3  E=7e-81 s/c=0.70 id=19% cov=70%
----------------------------------------------------------------------------------------------------------------------------------------YVHWGATSQDVIDTGLILQLRQALQLTQQSVNQLLATFAEQVFRYQKTVMPGRTWMQQALPVTLGLKLAGTLDALLRWQVRLEELLPRVLVLQFGGAA-GT-LASLKQDALPVAAELAKVLGLTLPDLPWH----TQRDRLLEIAAWYAGTGATLAKFAQDFALLMQTEVAEVSEPAV-AGRGGSSAMPHKRNPVICASILTAAQRTPG-LMATLYASQLQQHERALGGWQAEWETLPELIMLTGNIIAQSQELVQGMQVYPQKMRENLDITHGLLMaesvtlALAEFIGKQDAHHLVevlcRQAIEQQHALYDVLVNDTRITswlnATQIKNLLEPTAATGSAqvfidRVLARYKEQQNE
>UniRef50_Q0SJY5(30-480:493) Probable adenylosuccinate lyase n=1 Tax=Rhodococcus jostii RHA1 RepID=Q0SJY5_RHOSR  E=1e-80 s/c=0.67 id=19% cov=88%
-----RHEGGTMG-VGLDDDLLrdfFGNAEQRA----------IFDGPQRLQGWLDVERALAQTQAELGIIPAEAAQRISAHCQ--------SDLFDINKLRQHVNATQHPIVPMV--NALEKLVGTEFGQF--------VHYGATSQDIMDSGQALQLRQSLQGIERDVAAATKAAASLALKHRNTTQVGRTHGQHAVPISFGLKAATWVDELQRLQTRIAESRDRILTVQIFGAAG--SMAGYGDRAFEVKAGVASRLGLTEPVAPWH----ATRDRIAELGSLMALLAGVSERIAAEVIRLQSTEFGELVEPLQP-GHIGSSTMPQKRNPHLSEGIVAKA-RIAQSLSAGLLRNGAHQHERDMGAWAVEWLTVPELMVGSGAMAADLNHLLEGLQVNAECMRRNVGITggqvnaESLMMILDSSIGRDHAHhllvELTRSADLQNLNFSEVATADervaSHLSQDQIMKALDPAQYLG--------------
>UniRef50_Q960C6(37-449:503) SD07650p n=12 Tax=melanogaster group RepID=Q960C6_DROME   E=2e-79 s/c=0.72 id=21% cov=69%
-------------------------------------------------------KAYAEALHRAGLINAAEADKLVKNLELLRFDW-------------IEGTVKILPGDEDVHTVNERLLVEITGE-----LGQRLHTGRSRNDQVVTDMKLWLRKAIRETLGRLSRIIETATRQAELHLGVLMPGYTHLQRAQTVQFSHWLLSHAFALREDGQRLLELRDRANVLPLGSGALaGNPLGIDRLW-------LAERLGFSGVTA-NSMHAVGDRDFVVDFIYCCSMVSLHLSRLAEDLIIYSTT---EFDFIKLaDGFSSGSSLMPQKRNPDSLELIRGMAGVITANLTGIMMTIKGTPSTYNKDLQYDKQFCFQSFDKLSQ-VLEVTDGVLQTIQVKQESMEAAL-STDMLAT-----------------------------------------------------------------
>UniRef50_A1BG31(4-433:464) Argininosuccinate lyase n=9 Tax=Chlorobiaceae RepID=ARLY_CHLPD   E=1e-77 s/c=0.68 id=22% cov=70%
------------------------------------------------------------------------------------------------------------DIHTVIENRLKEKIGQTAG---------KIHSGRSRNDQVATDTRLYLRKKIAELQDAVQAMQQMLIGKAETYKETIIFGYTHLQRAQPISAGHYYLAWFSMFRRDRERLRDLLRRVNISPLGAAAfAGSTLPLNP-------ARTAELLAFD-DIFSNSIDAVSDRDILIEFISACSIMMMHLSRFAEDLILWSSYEFGYL-EIS-DAFATGSSLMPQKKNADIAELVRGKTGRVYGNLVSMLTIMKGLPLSYNRDMQEDKQPLFDTAETTISSMRIFT-KLIGHTTLKVERLRSLTSEDLSLATEIAEYLvsrnlpfreAHRITGKIVTFSIGEGITLPRITLEQfrtfSPLFDSAIYDSLKPEA-----------------
>UniRef50_D2RG73(32-408:470) Argininosuccinate lyase n=1 Tax=Archaeoglobus profundus DSM 5631 RepID=D2RG73_ARCPR  E=6e-77 s/c=0.77 id=28% cov=59%
---------------------------------------------------------------KCGHISRDDAKAIIRALLEIRDKG--YEAIPKEYE----------DVHEAIEAEVTKL----------TQAGKKMHTARSRNDEVATCLRMFARDRLLSIASAILDLRRVLLKRAEESIDVIMPGFTHLQYAQPTRLSHHILAYHDMLKRDFDRVIETFRRVNLSPLGACAfAGTSFELDRNYT-------AELLGFDGV-VENSCDAVASRDFLIESVFVATQLMLTLSRMAEEIVLWCS----EFDFIDLPeEYASTSSIMPQKKNPDVAELIRAKAGRLIGNLTGVMSIYKAMPLTYNRDFQEMNEILFKSLEI----------------------------------------------------------------------------------------------------
>UniRef50_C6I121(11-422:451) Adenylosuccinate lyase n=1 Tax=Leptospirillum ferrodiazotrophum RepID=C6I121_9BACT  E=8e-77 s/c=0.70 id=16% cov=66%
------------------------------------------------------------------------------------------------------------------------------------------HFGMTSTDLVDTAQNLLVRDALHIVADELRRFVGILREKALLYRTTLMVGRSHGIHGEPIVFGLKFLSWFAEFSRHAERLSRVRETMAVGKL-SGAMGTAVNIDPALEEEILGR----LGLAVEPVATQVV---SRDRHAELFSVLAGIGSSLERVAVEIRHLQRTEVGE-AEEPFRAGQKGSSAMPHKRNPVGSENITGLA-RLLRSYSVAALENVALWHERDISHSSVERVILPDAFCLIDYMLDRMGTILRDLVVYPERMKRNLEASGGLVfsqsvlLELVDsGLPREEAYRIVQDAAMttfrEGGLFRERLVAHPDFPKGEIwstrlDRAFDPLRFTH--------------
>UniRef50_D1B0U9(11-430:442) Adenylosuccinate lyase n=12 Tax=Bacteria RepID=D1B0U9_SULD5   E=2e-76 s/c=0.69 id=21% cov=80%
-------------------------------------------------AWLKVEKAATKAWNKLGLIPDSDCEKIVNNAK-----------FDIARIDEIEKVTRH----DVIAFLTS--VADSLGEES-----RWVHYGMTSSDCIDTAVALQMRDSLHVIIDDVKILMESLKKRAMEHKMTLMVGRSHGIHGEPITFGLVLAIWYEEIKRSLTNLENVMDVISVGQI-SGAMGNMAHSPIELEELVCEELGL----KPAPVSNQVIQ---RDRYAALMNALALLASSCEKIAVAVRHYQRTEVYECEE-FFEQGQKGSSAMPHKRNPVLSENITGLC-RMIRSYAIPAMENVALWHERDISHSSVERFILPDGFITTDFMLHRLNSVISKLVVYPENMMKNLNLTGGLVFSQRILLelplkgvSREDAYKIVQRNAMkvwadlqQGKPALNENKEslylqnllsdedlRAKLSEEEIRECFDYMYYT---------------
>UniRef50_C6JQT1(16-450:458) Lyase n=7 Tax=Bacteria RepID=C6JQT1_FUSVA   E=2e-73 s/c=0.64 id=18% cov=83%
-----------------------------------------------YQAWLNIEAALAKAQSEFGIIPKKAAENIEKAAKIEYIDFKLMDEIYKKIGHGF------VPFIKVFIKACDEISGEN-------ESSKYIHYGVTTQNIQQSGQLIILKQVHEKYLLICSKILENLAELAERNKDSVMAGRTHGKHATPITYGYKVSVWISDILASVERMKEVEKRVFKI-MMGGAVG-AFNTSGETGRKVQNRVAEILGMYSMEVPSR--NITSHKE--EYIMGLALLANNCHKIAEEVYTTSIEEYGEVSEAYE-EGTVGSSTMPQKINPKLAKGIIANSQKLY-SIVPMGLYSGSRPFEADSSSYMLFDAALEEAMELITEVLLRTEELTRTIQIFKERMYQNvlnnkgLDNSEYIMMKIAERLGKDKAHSIIYElaikSETEHKDYLQLLKENEVISevfnEEDIKNMLKPENYIG--------------
>UniRef50_Q0W7A4(39-440:497) Argininosuccinate lyase n=8 Tax=Archaea RepID=ARLY_UNCMA   E=3e-73 s/c=0.69 id=24% cov=65%
--------------------------------------------------------------ARQGIIAKEDAAAILKALAAIEHEG-------VDAVNIPAFEDVHMA----IESKLIKAVGE--------NAGGRMHSGRSRNDEVATCIRISARKELLGLMADLQDLRSALLALAEEHKETLMPGFTHLQHAQPTTLAHHMLAHASSFGRDFERLADALKFVNISPLGSAAfASTGYNLDRDLT-------AKLLGFD-RPMDNSMDGVSARDFILDLTSRMAIIEVNLSRLADELVLWST---SEFGFIELsDTYASTSSIMPQKKNPDVLELVRGRSGTVIGHMMAAFTIVKGLPYSYNSDLQEVTPQLLRAFEITRSSVRIMA-GAIQTITVKKEEMRR---------------------------------------------------------------------------
>UniRef50_B6CWI9(4-428:451) ToyF n=1 Tax=Streptomyces rimosus RepID=B6CWI9_STRRM   E=8e-72 s/c=0.64 id=17% cov=75%
-----------------PIDTgRYGSPRMRAL----------FTDRARYEAFVRVEGALATAQGRYGVIP--------REAAEAIAEQARTHRCSLERVAALEETSRHELFAAV----------QEFAESCGAH-GAWVHYGATSSDILDTALALQLTEAIALLEEDLRDLLTALLARIDAVGDHVMIGRTHGQQAQPVTLGFKLAIVLDRFVRCLERLAQAKERV-VMGKIAGAVGSLAGI-GAHGPEVQRETLRELGL---PEPAVCAQAVARDRIAEFFCWAGLTAACLEDLATEVRNLQRTEIGEVAEPFAEGGQIGSSAMPHKRNPVQSERICSLA-RLVRSLVGPALENVTSWHERDLANSANERFTLPEACVLLDEMLTTATYVIDGLRVFPDRMRHNLEHS----------------------------------------------------------------------
>UniRef50_Q1IIZ3(16-406:464) Argininosuccinate lyase n=1 Tax=Candidatus Koribacter versatilis Ellin345 RepID=ARLY_ACIBL  E=5e-71 s/c=0.69 id=22% cov=45%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNEQIATDLRLYVREQIDETTLLIADVIAALIERAESVGEAAMPSYTHLQRAEPVLIAHWLLAYAEMFFRDITRLADCRKRANLCPLGSAAVaGTFVALDRGY-------IATLLGFD-APTANSIDATSDRDFAIEFVQSLSVIGLHLSRMAEEMILFATT---EFGFLQLPEqFATGSSAMPQKKNPDSLELVRGKSAALLAHAMQLAVTLKALPLAYN--------------------------------------------------------------------------------------------------------------------
>UniRef50_A7H771(37-432:474) Argininosuccinate lyase n=4 Tax=Anaeromyxobacter RepID=ARLY_ANADF   E=1e-70 s/c=0.68 id=22% cov=45%
--------------------------------------------------------------------------------------------------------------------------------------------GRSRNDQVALDERLFIVAACERCDAALGRLQRALVARAREHEKTILPGYTHLQRAQPVSLAHHLLAHVEAFARDRDRLADVRRRAAVSPLGSGALaGTTLPLDR-------EATAKALGLAGVT-QNSLDAVSDRDSAIELLFACALAAVHLSRVGEEIVLWTTK---EFGFMTLaDAFATGSSLMPQKKNPDVGELARGRAGRAIGDLVALLAIVKSLPLSYNRDM-----------------------------------------------------------------------------------------------------------------
>UniRef50_D1NTX5(49-450:493) Argininosuccinate lyase n=2 Tax=Actinobacteridae RepID=D1NTX5_9BIFI   E=1e-70 s/c=0.67 id=19% cov=55%
--------------------------------------------------------------------------------------------------------------------------------------------GRSRNDQIATLIRMWMRRKARVIASDVLDLCDALMAQANAAGKTVMPGRTHMQHAQPVLLAHQLMAHVWPLLRDVSRLRDWDARCDASPYGSGALaGNTLGLDPTM-------VARELGFSTVT-SNSIDGTAARDLVAEFAFINAMIGVDLSRLSEEIIIWNTQ---EFAFVTLhDSYSTGSSIMPQKKNPDIAELARGKAGRLIGDLTGLMATLKGLPTAYARDLQEDKEAVFDQVDTL-EVVLPAFTGMVRTMQFDHERLEEQAPTGFALATDIA--------------------------------------------------------------
>UniRef50_Q7MJB9(31-441:459) Adenylosuccinate lyase n=6 Tax=Gammaproteobacteria RepID=Q7MJB9_VIBVY  E=5e-66 s/c=0.62 id=17% cov=79%
----------------------------------------------------------AEAQAELGLIPHSAASAIKQVCDIRHLDWARLAQDTQTV------------------GMAIKPLVDQLSEQGNDEVKQYLHWGCTTQDLLDTSLAMRLKQTLHIVRQQLVALGDQLASMALHHKRTVMVARTNAMDALPTTWGLQVSGYLQEITRHLTRLDELYPRVTT-GLYGGAVGNLSSIGSHGLAVRQRLFAKL-----ELTEPKGLGNASLDNIVELIQFFALIHGTLCRIANDTELMGR---AALGEVCEGESGGGSSTMPHKANPRAA-NMIQTLSRMGWMYASGAPNLMDQQDVRAASMRVLNWSLVPEASLAVSTALERGERLVANLIVNQDKMRSNFSASRNFIMSEAvmmkaaekvgRSMGYSCVKMAIAQAPEQG-DLAQILKQnpevSAILTDQEIDAACDPQHYLG--------------
>UniRef50_A4AHM6(92-413:478) Argininosuccinate lyase n=6 Tax=Actinobacteria (class) RepID=A4AHM6_9ACTN  E=1e-65 s/c=0.79 id=21% cov=55%
--------------------------------------------------------------------------------------------------------------------------------------------GRSRNDQIATLVRLYLLDHAGAIAAMVVDLIDAIVAQSEKHNSAIMPGRTHLQHAQPVLLAHHLLAHAWPLVRTLERLRDWKARASTSPYGSGALaGSTLGLDP-------ALVARELGLA-RPTENSIDATASRDVVAEFAFITAQLGIDISRLSEEIILWNT---REFDFVQLdDAYSTGSSIMPQKKNPDIAELARGKAGRLIGNLTGLLATLKALPLAYNRDLQEDKEPVFDSVETL-EVLLPAFTGMIATLRFNTARMAELAPQGFSLAT-----------------------------------------------------------------
>UniRef50_A4X707(13-410:428) Adenylosuccinate lyase n=3 Tax=Actinomycetales RepID=A4X707_SALTO   E=1e-63 s/c=0.62 id=18% cov=60%
-----------------------------------------------------------------------------------------------------------------------------------------VHLGMTSYDLVDTALGATLARACDVLLEAVVRLRGVLVDQALAHWETVCIGRTHGMHAEPTTLGHKLAGFAFATDRSVRRLRAARSEV-AVGTISGSVGTYALIDPF----VEEHVCAELGLGVEPAPSQVVA---RDRHAQLLHALATLGACVEQLATEVRLLSRSEVREVEERRTAGYQ-GSSAMPHKRNPTASERLVGLA-RLLRGYAGTTLENVALWHERDLSHSSVERVVLPDAMIVAHYQTSRAADLVAGLEVFPDRMRAMVEGNGGvfyssavLADLLAGGIERERAYRSVQAAA----------------------------------------------
>UniRef50_UPI0001AF22AB(27-477:482) 3-carboxymuconate cycloisomerase PcaB n=1 Tax=Streptomyces roseosporus NRRL 11379 RepID=UPI0001AF22AB  E=1e-62 s/c=0.54 id=18% cov=83%
------------------------------------------------QAMLDAEAALARAQSTLGTVPP--------GAAAAITEAARAELFDVRALALAARETANPVVPLVRELTRLVALGDPA-------AAEYVHRGSTSQDVFDTGAMLVSARVARLLLADLRRTADALYDLAAAHRDTPMAGRTLALHAVPTTFGLKAAGWRDLVLDAADRVAGVLEGGLPVSLGGAAGtlagyleyaaiaaagdapagpdrGTSAGLDRgGYLDALNGAFAAETGLARQRTPWH----SLRTPVADLAAALAFTTGALGKIAVDVQSMVRTEVDEVAEPAV-AGRGRSSAMPHKRNPVLATLIRSAALQVP-ALAAGLTQCMLAEDERSPGVWHAEWPLLRGCLRLAGGAAHTAVELAEGLVVRPDRMRDNLRvtgsqmASERVAAALASGLGRGRAQELLAEASAtarhTGRPLAEVLAALpgvaACLDPRVLSVLLDPLGYTGAA------------
>UniRef50_D1CE80(15-413:448) Argininosuccinate lyase n=1 Tax=Thermobaculum terrenum ATCC BAA-798 RepID=D1CE80_THET1  E=3e-62 s/c=0.61 id=21% cov=53%
-----------------------------------------------------------------------------------------------------------------------------------------IHTARSRNDQVLVDLRLYAKAKILELESALLQCAESLVEFASKHEHVPMPGYTHMQRAMLSSVGTWAGAFAEALLDDLKLLETAYELNDQSPLGSAAsYGVPLPIDRQY-------VADKLGFAKVQNNVLYAQNARGKFEALVVQAISQIMLDLSKLAQDILLFTTAEYG--FFTISDSFVTGSSIMPQKKNLSMMELIRAKANMALGYQQQMMSVLSGLPSGYNKDYQETKKPFMEAIQLALDSLKV-AELTISNLSPNKDKL-----------------------------------------------------------------------------
>UniRef50_Q9Z4S3(2-387:398) Argininosuccinate lyase n=8 Tax=Thermotogaceae RepID=ARLY_THENN   E=3e-60 s/c=0.61 id=22% cov=52%
--------------------------------------------------------------QRTGLLTQEEQKKIEEALNELLHLVE-EGKFQIKPEDEDCHTA--------IENFLVKKLGET---------GKKIHTARSRNDQVLTALRLMYKDELKKIKDLVVELQKSLDGFIERFGQIKFAGFTHTRKAMPTDFATWAGALRDALQDDLKLLETVYDIIDQSPLGTGA-GYGVPI-----EVDREFTAKELGFSRVQWNPIYTQNSRGKFEYLLLHVLSQISYDLNRFASDIIFFS---LPEIGFLKLPkELCTGSSIMPHKINPDPLELV----------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q1R0U7(14-442:444) 3-carboxy-cis,cis-muconate cycloisomerase n=1 Tax=Chromohalobacter salexigens DSM 3043 RepID=Q1R0U7_CHRSD  E=5e-60 s/c=0.55 id=17% cov=85%
------------------------------------TGREKCSAQDLVVAMLDVELALAAEQERLDMLPK--------GTTETLGEYLTTEVFDIEALADDTAKGGNAAIPFV----------KQAKAALPDTLKPYFHRGATSQDIVDSALMLLLKPRLARCRRLLTASIDDGRSLMVAHRDTTMIGRTLMQQALPITFGAKVGQWAWGLHQAGERLDDVLTGGLYVQFGG-AVGVHSGLD-DAGVAIMTGMASRLGLAEPWLPWHTD----RQPIHSLGCAIDAVAVAAEKVALDVALLTQTEIGELAEPAE-AGVGESSSMPHKRNPVGCARIRAAARQIHAAL-SVLTNAGAQPLERGLGEWHAEWAPMLDAALLLEGALETLQHLLSGLEVNDQVMARNLGVTGGAIMAepaarvLQSILSNDEARRVAREASENarraGVDYAEALLAHedvagSAIDADALRQAVRPESYIGSSR-----------
>UniRef50_A8S1Z4(37-434:517) Putative uncharacterized protein n=1 Tax=Clostridium bolteae ATCC BAA-613 RepID=A8S1Z4_9CLOT  E=2e-59 s/c=0.58 id=24% cov=56%
------------------------------------------------------------------------------------------------------------------------------------------HLARSRNDMCVTWSHMAVRDGLLQAMEQFLYLKNAIVLFAEEHKDTLYVIHTHTQHAQPGLLGHYFLGAADMLERDFKRLCRAYDAVNQSPMGAAAVTTT------GFPVSRERVAELAGFSGM-IENAYDAIGNSDYLTQTASALGLCALDMGRIVTDLLLWATQEMNMIH--VADGYISISSIMPQKRNPIALEHLRSSLSVLKGMADTVLTGFLKSPYGDISDYEDIEDSVFGCLELFQKNVQLFRA-VISTLEVNKELLESRAYESFSVVT-----------------------------------------------------------------
>UniRef50_Q05911(40-456:482) Adenylosuccinate lyase n=68 Tax=cellular organisms RepID=PUR8_YEAST   E=3e-59 s/c=0.56 id=19% cov=65%
------------------------------------------------------------------------------------------------------------------------------------------------------------------IIPKLVNVINRLAKFAMEYKDLPVLGWTHFQPAQLTTLGKRATLWIQELLWDLRNFERARNDIGLRGVKGTT-GTQasflalFHGNHDKVEALDERVTELLGFDKV--YPVTGQTYSRKIDIDVLAPLSSFAATAHKMATDIRLLANLKEV---EEPFEKSQIGSSAMAYKRNPMRCERVCSLARHLGSLFSDAVQTASVQWFERTLDDSAIRRISLPSAFLTADILLSTLLNISSGLVVYPKVIERRIKGELPFMATENIIMAmveknasRQEVHERIRvLSHQAAAVVKEEGGENDLIERVKRDEFFKPiweelDSLLEPSTFVGRAPQQVEK
>UniRef50_D0MJ53(13-393:439) Argininosuccinate lyase n=1 Tax=Rhodothermus marinus DSM 4252 RepID=D0MJ53_RHOM4  E=6e-59 s/c=0.61 id=28% cov=40%
-----------------------------------------------------------------------------------------------------------------------------------------IHTGRSRNDQVLTAIRLFLKDGLREAGRRVARLVEQLCELGTAYNDALMPGYTHLQQAMPSTAGLWALGYAELLLSDLAALRHAFDQVDVSPLGSAA-GYGVP----FLELPREEVARRLGFRALQLHVTAVQLSRGKLELHAAHALVQVGATLNRIASDLVLFNSQ---EFGFVELpPECCTGSSIMPQKQNPDVPELV----------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q02CF9(18-427:427) 3-carboxy-cis,cis-muconate cycloisomerase n=1 Tax=Candidatus Solibacter usitatus Ellin6076 RepID=Q02CF9_SOLUE  E=1e-58 s/c=0.56 id=16% cov=83%
---------------------------------------------SVLQAMLDFEAALARAEARCGVIPASAVTA-----IAAAAIAEGFDLSELTRLSLRAGTP---------AIPLVKMLTARVRAIDPVAAG-FVHWGATSQDVADTALVLLLRQAVPILQADHERTMAALHGLSERNAGAVMLGRTLLQPASPVTFGLKAAGWYAALRRGWDRVSSRFDEALCLQFGG-ASGTLASLD-DRGMSVGEALASELALREPDAPWH----GYRDRLAALMAALTIYTATLGKIALDVALLMQFEVGEAFEPGGEGRGGS-SSMPQKRNPTACMLTLAAAKRVPGLL-ADFVVGMVVEHERALGGWQAEWPLVYGIVQSAAIALESMAEVCDGLNVDVAKMRANVESTKGAIFAeravllLTPELGREVA----------RRQVEDAIRETG--SPPDLPGLRDPEQYLGSAEAFRKRQMQGDK
>UniRef50_A8F694(22-425:479) Fumarate lyase n=1 Tax=Thermotoga lettingae TMO RepID=A8F694_THELT   E=1e-58 s/c=0.57 id=23% cov=66%
------------------------------------------------------------------------------------------------------------------------------------------HTARSRNDIDATIFRMALRNVLIQFEKELLNLIKQFIRKAGQNIDTVFLLYTHGQPAQPSSFAHYLLAFSGELTQVSKKLIETFDIVNECPMGAGAItTTGFSIDR-------NLVSNYLGFN-RPLENSYQAISTSHWITLPGALLRNLMIDITRFIQDIMHKSSSEVGVLQFPN--ELVQISSIMPQKRNPVVLEHLRLRANMAANAFSNIENVFLNVPYQdVNENGDFVLREFLNAMDI-SNQVLILLSEMVEKVIVRTDRVREIAAQFGATSTELADelvrrfGISFRKAHLIVSEVVKTGLNFenfsnviKEHLKEKPemEINPEEFQHILSCEHFIE--------------
>UniRef50_P21265(7-467:485) Adenylosuccinate lyase n=167 Tax=cellular organisms RepID=PUR8_CHICK  E=3e-58 s/c=0.49 id=17% cov=66%
---------------------------------------------------------------------------------------------------------------------------------------------------------IVLRDGFNLLLPKLARVISRLADFAETHADLPTLGFTHYQPAQLTTVGKRCCLWIQDLCMDLQNLERARDDLRFRGVKGTT-GTQASFlqlfegDHSKVEELDRLVTAKAGFKRSYMVT--GQTYSRKVDIEVLSVLASLGASVHKICTDIRLLANLKEI---EEPFEKDQIGSSAMPYKRNPMRSERCCSLARHLMTLVLDPLQTASVQWFERTLDDSANRRVCLAEAFLTADIILSTLQNISEGLVVYPKVIDRRIRQELPFMATENIIMAMVKAGGNRQDCHEKIRvlsqqaaavvkqeggdnDFIARVRADPYFSPihEHLDSLLDPSSFTGraPQQVAKFLKEE---
>UniRef50_A6X1U1(92-474:504) Argininosuccinate lyase n=2 Tax=Ochrobactrum RepID=A6X1U1_OCHA4   E=7e-58 s/c=0.59 id=20% cov=66%
------------------------------------------------------------------------------------------------------------------------------------------HTARSRNDIDHTLFKLGLKARIDTLMTQARNLLDAMIAAAEREKETLIVAYTHGQPAQPSTFGHYLSAAVEVLIRDMERMEATRAIVNLSPMGAAAITTsGFPIDR-------ARVASLLGFA-APLPNSYSCIAAVDYITSTYSALELMFVHLGRLIQDFQFWTS---FEVGQIYVPnAFVQISSIMPQKRNPVPIEHMRHLASQTMGRARTVLDVMHNTPFTDMNDSEGETQAMGYEAFASAGRVLDLLAAFIGAIRIDPARVAENIRRSCITITELADslvrieGLSFRQAHEIAARvaravvamgggLEKDGfepflDAFRESAGREPSFGREKFEELVSPQHFV---------------
>UniRef50_A1QZL0(37-445:467) Adenylosuccinate lyase n=10 Tax=cellular organisms RepID=A1QZL0_BORT9  E=3e-55 s/c=0.53 id=20% cov=64%
---------------------------------------------------------------------------------------------------------------------------------------------------------VQIKEALLLIENKLLKLINTLKKFSIKHKNLVTLAYTHLQEAQLTTLGKRSSLWLQSLIFDFEELKFIMSNMRFRGVKGT-VGNQSSFKELFASNFEKvkdldiNLAKKMGFDKVYQITS--QTYDRKFDSSILNFLSNLAQSAHKITNDIRFMQH--LKEIEEHFEP-HQIGSSAMPYKRNPIYSERIASLAKFIMSLQSSGGFIAATQWLERTLDDSACKRLNIPQAFLAADATLILLSKVFNNIRVNKKMIEKHVktEMPFILTEDIlmkatknggDRQILHEKIriySMKVKENIYSGTTendLIKLILNDQsfKLTSKDIDEILNPNENIG--------------
>UniRef50_D1W006(107-543:544) Adenylosuccinate lyase n=2 Tax=Prevotella RepID=D1W006_9BACT   E=9e-52 s/c=0.47 id=18% cov=55%
-----------------------------------------------------------------------------------------------------------------------------------------IHFGLTSQDINNTSVPLSIKEALHEvLVPCIEELIEQLEAYAAQWKDVPMLAKTHGQPASPTRLGKELMVYVYRLREQLMLLETCK----MSAKFGGATGNYNAHHVAYPAIDWKDfgnrfVQEKLGLQREQYTTQI---SNYDHMGAFFDALRRINTIVLDMDRDFWMYIS---MEYFKQKIKAGEVGSSAMPHKVNPIDFENSEGNLGMSNAILQFLAQKLPVSRLQRDLTDSTVLRNVGVPIGHTMIALQSTLKG-LRKLILNEDKLYQDLDKTWAVV------------------------------------------------------------------
>UniRef50_Q3MNP2(20-360:401) Beta-carboxy-cis,cis-muconate cycloisomerase n=1 Tax=Terrabacter sp. DBF63 RepID=Q3MNP2_9MICO  E=3e-50 s/c=0.59 id=19% cov=57%
--------------------------------------------AALVGAMLQVEVAWLRALARVGAVDSDLAGQVAKVTQD----------WEVDMAALAAESEAAGNAVVPLVRLFQEAVGQ--------DAARVVHRGLTSQDVVDTALVLLARDALVRMGDDLAATSRALAALAGRHRSTLMVGRTLTQHAVPITFGLKAAQWLAGVLDAVAQVDDILGTLPV--QCGGAAGTLALVGEltDEPLAAARAFADELALDWPGVPWH----TNRSVITRIGSAVVSTCDALGVVAADVSTLSRPEIGELREGTV-AGRGGSSTMPHKRNPVLSVLIRSVALQ----------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C4DQU1(18-361:454) Adenylosuccinate lyase n=1 Tax=Stackebrandtia nassauensis DSM 44728 RepID=C4DQU1_9ACTO  E=4e-49 s/c=0.58 id=18% cov=58%
-----------------------------------------------------------------------------------------------------------------------------------------VHYGATSQDIMDTAMMLVAHRATAVIVDNLAHAAEAAASLTERHRDTLLIGRTLGQHAAPTTFGAVAAGWLSGIDAARDQLRSARFELAA--QLGGPVGT-LEPYGTQGLRVLADFAHRLGLADPGLPWHTE----RTRVTRLASALATGAGTLAKVAHDVSVLGSSDVGELRE----GSGGGSSAMPHKHNPADSVLVLANVRRTPG-LAATMFAALESELQRPAGAWQSEWQTLSQLLRCCGGASSRASSLLSGLRVDTGRMRSHLDATGGLLRAgavadqLAPALGRREAHEL---------------------------------------------------
>UniRef50_Q11F19(12-450:499) Argininosuccinate lyase n=2 Tax=cellular organisms RepID=Q11F19_MESSB  E=2e-47 s/c=0.44 id=18% cov=68%
-----------------------------------------------------------------------------------------------------------------------------------------IHLGRSSADLAGVSRRIVLRTAVLSMARQLIDVQLTILNTAPDHLDCIIPAYTHGQPAQPTTYAHWLMMWANVFHRDTQRLLGGLDRLNLSPAGAAvATGTDFAIDRS-------RVATLLGFDGILV-NTMDATLSNDVFAEYVSIFSLLCANMGRLAEDLLFWSTQE-AGIAVIP-DRFCDTSSIMSQKRNPSFLHELRA-----MGAEAASTLLLVSGTEFGTTGQSVHARKTAEnAVWALVGKIikrLPQMADLIASTEIDPQRAMRLTENSWSQATDVASALVRHlglnwrEAHHvvsiLVRLATERRLPpdqvdlaLLRTALAEAQIAAEDLDG-FDIADAVDVRAFVERRTNE---
>UniRef50_C2PYS8(54-393:507) Argininosuccinate lyase n=2 Tax=Bacillales RepID=C2PYS8_BACCE   E=7e-47 s/c=0.56 id=25% cov=38%
------------------------------------------------------------------------------------------------------------------------------------------HMDRSRNDFQACAQLIFGRAQWLELMQNLIELIESMDILANQYREVGMPGYTHYQSAQIITPGFYLSTINQELLQTLKRWIRVYDDMNQCPLGSGAMaGVELDWDRD-------RLASLLGFHQVRL-TALAAVASREWVLQASSELSIFSVLISRFTTDLMQWGSSEMN---FINLPDELSGiSSAMPQKKN-----------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6G4E8(10-414:479) Adenylosuccinate lyase n=2 Tax=Bacteria RepID=A6G4E8_9DELT   E=6e-46 s/c=0.46 id=19% cov=68%
--------------------------------------------------------ALARAESALGLpVSQAQIEALV-AARETIDFERVAE-------------IEASLRHDVMAHV------HHFGDVAGPEAAKIIHLGATSCFVTDNAELVMIREGLELLMDRLYTCLTQLRSFAQTWRAEPIQAYTHFQPAQLTTVGKRACLWAQDLAFDLETLEQLVARLPMRGVKGTTgtqasflqLFTSHDDPNAAIRELDRRVCEAMGFDRSIAVS--GQTYTRKIDTWVVSALADVAGSAAKFASDMRLLAHEREL---EEPFGKKQIGSSAMAYKRNPMRSERINALARFVHSLATSPRETHGNQWLERTLDDSANRRLVITEAFLATDAILNLVVDVTAGIVVNPAMLAKN--------------------------------------------------------------------------
>UniRef50_A8HWY4(27-338:354) 3-carboxy-cis,cis-muconate cycloisomerase protein n=3 Tax=Rhizobiales RepID=A8HWY4_AZOC5  E=4e-44 s/c=0.58 id=20% cov=54%
-----------------------------------------------IRAMLAFEAALARAEAIHGLIPAEAAETIATVCVQFQPDV--------------AALARGVASDGVVVPALVRALRAAVGP----EAAPHVHRGATSQDVIDTSLMLRLKPLAARFCTRLGAILARLAALDAAFGERALMGHTRMQAALPITVSDRLRSWSGPLAPLMLRL----DRLSFPVQFGGAVGT-LEGLEGKGAQVRAALAAELDLEDTP-----QWHSTRTVITDLGHLLALITGGLGKMGQDIALMAQA-----GDDITLSGGGGSSAMPHKQNPVAAETL----------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q2K050(35-354:359) 3-carboxy-cis,cis-muconate cycloisomerase protein n=43 Tax=Alphaproteobacteria RepID=Q2K050_RHIEC  E=1e-41 s/c=0.54 id=21% cov=54%
-----------------------------------------------IRAMLSFEAALARAEAAHGLIPAEAARKIAEACTGFSPD--------------LASLRSAMAKDGVVVPDFVKQLRAKVGE----EAGKNLHLGATSQDVIDTSLMIRLKAVVFLFAGRLSAIIAALEGLDRQFGGNRLMGHTRMQAAIAISVSDRLNVWRAPLATYRDRLTEQSFPVQF----GGAAGTLDKLGPQ-GPAVRASLAQELGL-----SDTRQWQSARLPIADIAGLFASISGSLGKIGQDIALLA--EMGGEIEVS---GGGASSAMAHKQNPVAAEVL----------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C6WLF2(36-403:527) Fumarate lyase n=5 Tax=Bacteria RepID=C6WLF2_ACTMD   E=4e-41 s/c=0.46 id=22% cov=57%
-------------------------------------------------------------------------------------------------------------------------------------PNWHV--DRSRNDLQACAQLMAARDRLAALAGQVLGMAAAARRVAARHLDTPMPGCTHYQAAQVTTPGFHLAALGERLLHTSRRLLATFDGTDACPLGAGAL-TGQHLPWD-----RERMAALLGFTRPGGSALTD-VASRAFVAEITAELSLFGITASRFATDLITWAG---AGHGFVDLPDELSGiSSAMPQKKNFPVLERIRGRTAHLTSCHVDVALAQRGTPYTNLVEVSKEAGAQFHDALDTAGSVVRLFTAVLDGLVFRADRMRAACEReylgGFALATLLT--------------------------------------------------------------
>UniRef50_UPI0001B4D80D(36-317:402) 3-carboxy-cis,cis-muconate cycloisomerase n=1 Tax=Streptomyces lividans TK24 RepID=UPI0001B4D80D  E=5e-41 s/c=0.61 id=23% cov=54%
--------------------------------------------RAYLRALLDAEAALTRAQAALGLAPAEAADA-------VGAVAADPAAFDARSLAERARGGGNPVIPLV--ADLTKAVGEPYGPY--------VHRGATSQDILDTATMLVAARTLDLLLPDLARTERALARLAAEHRDTPMPGRTLTQHAVPTVFGLKAAGWRALVLDARDRITAVRDALPA--QLGGAAGT-LAAFEAYGATDPTALpaayAGELGLRAPVLPWH----TLRTPIADLAGTLAFTAGALGKIAVDVLTLSRTETGEVAEGGGGGSSA----MPHKANPV---------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q7KWJ4(13-461:471) Adenylosuccinate lyase n=63 Tax=Haemosporida RepID=Q7KWJ4_PLAF7   E=4e-38 s/c=0.36 id=16% cov=61%
------------------------------------------------------------------------------------------------------------------------------------------------------------------IIPNIQNIIDKLKEFSFNYSDVSLLSKTHGQPASPTTFGKEMSNYYYRLYKHINKLKNIEIYVKFN----GAVGNFNAhkvCDPniDWIDNIKYFIETYFNLHFSLYCTQI---QDHDYICEISDTLARLNYTLIDLSVDMWLYISSNVLKLKVIQ---KEIGSSTMPHKVNPIDFENAEGNLHLANSLFKLFSSKLPISRLQRDLSDSTVLRNLGSSFAYSLISYKSLLRG-LNKIDVDQNVMNEQLNQNWcTLAEPIQIIMKKyniADSYEQLK-NFTRGKSIDKQCMyqfiqqNCSHLPKNAIDELMNltPHNYLG--------------
>UniRef50_C2EB52(1-167:182) Possible aspartate ammonia-lyase n=1 Tax=Lactobacillus ruminis ATCC 25644 RepID=C2EB52_9LACO  E=2e-35 s/c=0.92 id=41% cov=34%
----MRIESDSLGTKAVDDAAYYGIHTERARENFPVTSRPV--DGRLVRNLILVKEACANANAETGRLAADKHRMIVGACEAILDDFdRFASELRTPAIQGGAGTSTNMNANEVIANLAAEMAGAKKGTYELIHPNDDVNMAQSTNDVYPTAGHMALVEYTTDLLDQLEK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q97A54(105-356:437) Argininosuccinate lyase n=1 Tax=Thermoplasma volcanium RepID=Q97A54_THEVO  E=2e-30 s/c=0.54 id=19% cov=31%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PGYTHFQQAMPFTFKSFMNSVLLLLERNILNVHDFFQKIR-INVYGYGSGYGSPISAKF-----DKMGELLGLRYDHKNPIFLSSLYPQTLLEASQLIVTIMMPLSRLSSDTINYYSRGIMDI----PDEFTTGSSLMPNKRNPDYLEMIQGLAAESVG-------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A5G1E3(161-422:450) 3-carboxy-cis,cis-muconate cycloisomerase n=1 Tax=Acidiphilium cryptum JF-5 RepID=A5G1E3_ACICJ  E=2e-24 s/c=0.44 id=18% cov=55%
-----------------------------------------------------------------------------------------------------------------------------------------IHRGGTTQDIVDTGLILQLRDGFLLLEADLDAAAAAAARLARAHAATPMIARTLLQPALPATFGLKAAQWLAALDDARAALRDAARQALRPQLGGAA-GT-LDGFGTRADAAATAFAAALGLDPAPLPWH----TSRAPLARLAATLAAALGTAGKIATDTALMMQAECAEAA-EPAAPGRGGSSAMAHKRNPTLAVAIRAAALRAP-PLAATLLAALPQEHERAAGAWQAEQSVWPELMRLASGTLAALAELLAGLTVDEAAMARNLAH-----------------------------------------------------------------------
>UniRef50_B2A2B6(10-476:479) Fumarase n=35 Tax=cellular organisms RepID=B2A2B6_NATTJ   E=1e-136 s/c=1.04 id=49% cov=98%
-----RVECDSLGSKEIPKDAYYGIQSKRAQENFPLSGYRVH--PELIKAMGKVKYASVVANMKTGKMPNKSGEAIKQACEE-MSSGKFFDAIVVEAIQGGAGTSINMNVNEILANRAIEILGHEKGDYDVVSPNTHVNMSQSTNDVVPTSFKLAVITMREDLISKLENLYQTLSKKEQEFDKVIKTGRTHLQDAVPIRLGQEFGAYARFVKRDIERISNSIEALKTVNLGATAVGTGLNADSKYINTAIEELREITGIDLEISDHLVDATQNTDAYVHVSGALKTAALNMSKMANDLRLMSSGPRCGFKEIKLPAVQPGSSIMPGKVNPVIPEVINQICFQVAGNDHTISMASEAGQLELNVMGPVLFRNMFESMEIIANGAHILSEKCIKGIEPNHDRCNELVENSIGIITALNPHIGYETASEIAKEVLETGRSVRDVILEREILTEEEIEDILDPKEMTEPGIAGKKKND----
>UniRef50_P07954(48-509:510) Fumarate hydratase, mitochondrial n=26 Tax=cellular organisms RepID=FUMH_HUMAN  E=1e-133 s/c=1.03 id=39% cov=97%
--NSFRIEYDTFGELKVPNDKYYGAQTVRSTMNFKIGGVTERMPTPVIKAFGILKRAAAEVNQDYGLDPK-IANAIMKAADEVA-EGKLNDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKIPVHPNDHVNKSQSSNDTFPTAMHIaAAIEVHEVLLPGLQKLHDALDAKSKEFAQIIKIGRTHTQDAVPLTLGQEFSGYVQQVKYAMTRIKAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAALTGLPFVTAPNKFEALAAHDALVELSGAMNTTACSLMKIANDIRFLGSGPRSGLGELILPENEPGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARLLGDASVSFTENCVVGIQANTERINKLMNESLMLVTALNPHIGYDKAAKIAKTAHKNGSTLKETAIELGYLTAEQFDEWVKPKDMLGP-------------
>UniRef50_Q9ZLI5(1-468:468) Aspartate ammonia-lyase n=388 Tax=cellular organisms RepID=ASPA_HELPJ  E=1e-132 s/c=1.01 id=56% cov=98%
----MRIEHDFIGQMEISDEVYYGIQTLRASENFFITNDKLCSYPVFIKSFAQVKKAAALANAQLGLIDEKLKIAICHACD-LLVDGKYHDQFIVDMIQGGAGTSTNMNMNEVIANLALEYMGHQKGEYQFCHPNDHVNRSQSTNDAYPSALKIAIYERLSNLVAPMKALRDAFAQKAKEFAHVIKMGRTQLQDAVPMTLGQEFETYALMVDRDIEQVLDARNWVRELNLGGTVIGTGINSHPDYRSLIEKKIQEVTGRPFVMANNLIEATQSTGAYVQVSGVLKRIAVKLSKVCNDLRLLSSGPRAGLNEINLPKMQPGSSIMPGKVNPVIPEVVNQVCFAVIGNDLSVALAAEGGQLQLNVFEPVIAYKLFHSFVILGRAIETLTTKCVEGITANEKICHDYVFNSIGIVTALNPHIGYEKSAMIAKEALKSDRSIYDIALEKKILTKEQLDDIFKPENMLSP-HAFKKHKD----
>UniRef50_B0S039(19-490:507) Aspartate ammonia-lyase n=113 Tax=Bacteria RepID=B0S039_FINM2   E=1e-131 s/c=1.00 id=48% cov=99%
---DYRLESDSVGEKQVPKDAYYGVQSLRGMENFPITGRTLH--EELIYGLTIVKKACAIANHRAGIMREDVKNAIVYACDQILK-GEYHDQFLTDPIQGGAGTTANMNANEVIANIANEKLGGGLGTYEYVHPNDHVNMSQSTNDVFPTAGKIATLRLLIKALNELKQLEISLLNKSVEFDDVLKMGRTQLQDAVPIRLGQEFHAYYSVIKRDIKRIRRSSDQIESINMGATAIGTGVNVDKVYFTNIVPILAELTGFDLHQAEDLIDGTNNLDGLVEISSAVKSTAVSLSKMASDLRLMSSGPKTMVGDIELPPRQNGSSIMPGKVNPVIPEVVNQVVFRIIGNDNTVTMCAEHGQLELNAFEPVLFDSLFESISILTNAVRTFRENCIIGIKPNRQKLSNDVEKSVGIVTALVPHIGYKKSAEIAKRALSTGITVRNIVLDEKILTEDELKEILDPIAMTMPGIAAEYLIKQKQQ
>UniRef50_B8DKU3(6-466:521) Fumarate lyase n=90 Tax=Bacteria RepID=B8DKU3_DESVM   E=1e-130 s/c=1.02 id=53% cov=97%
---EYRIERDSLGERKVPAHAYYGVQTLRALENFDVTGLTIGRHPRFVQALASVKKAAALANMELGLLDGDVGQAIVQACREV-REGRFDEQFVVDIIQGGAGTSVNMNANEVIANRALELMGRTRGEYGVVSPLNHVNLSQSTNDVYPTAFRIALVWYARDLGVSLRELRDAFHAKGEAFADVIKMARTQLQDAVPITLGAEFAAYGVTVGEDIDRLAEVARLLCEVNIGATAVGTGINTVPGYAPLVCDRLADITGLPLSLSPNLVEATSDAGAYVTLSGLLKRVAVKLSKICNDLRLLSSGPFTGLGEISLPAVQPGSSIMPGKVNPVIPELVNQVCQQVIGNDLTVTLAAEAGQLELNVFGPIMACNLFQSLEILTRAARILRVRCVEGITANRERCLELLHGSLGMVTALAPVIGYEAAATVVKDARATGRTPRDLLVERGLMRSEDYDDLMDPAKMLGP-------------
>UniRef50_C3PG94(41-510:510) Aspartate ammonia-lyase n=7 Tax=Bacteria RepID=C3PG94_CORA7   E=1e-129 s/c=0.99 id=65% cov=99%
-----RTETDLLGSVEVPSDAYYGVHTLRAIENFQISYVTINTIPDFIRGMVQVKKATAMANRRLHVLPKKKAEAIIWACDQILEEGRCMDQFPLDVFQGGAGTSLNMNTNEVVANLALEYLGEEKGSYDVINPNDDVNMSQSTNDAYPTGFRLGIYYAMEDLIERIDTLQAAFHAKGNEFVDILKMGRTQLQDAVPMTLGDEFKAFAHNLAEEQAILRDAQKRLLEINLGATAIGTGVNTPAGYRHQVTAALSEVTGLEIKTARDLIEATSDCGAYVLLHSTIKRAAMKLAKICNDLRLLSSGPRAGLAEINLPPRQAGSSIMPGKVNPVIPEVVNQVCFKIFGNDHVVTMAAEAGQLQLNVMEPVIGEALFQSIRIMGNAVDTLREKCVVGITANADVCRAYVENSIGIVTYLNPFIGHHNGDMIAKESLKTGKGVKELVLEKGLLDEETLNKVLSVENLMHPEFRGQLYIDE---
>UniRef50_C9R7S2(2-472:498) Fumarate lyase n=1 Tax=Ammonifex degensii KC4 RepID=C9R7S2_AMMDK   E=1e-128 s/c=0.98 id=44% cov=98%
---EYRWERDSLGEKAVPKEAYYGIHALRAKENFPVSGQK--PHRELLWALGVVKQAAASANTAVGLLPPEKGEAIERAAAE-FASGRFDDQILVDVYAGGAGTPLNMNVNEVIANRALEILGFEKGSYHIIHPLEHVNLSQSTNDVFPTAVKVAAIKLVRRLSQAMARLQGALQRKEKEFASVLKIGRTEMQDAVPITLGQEFGAWAEAVARDWWRLYKVEERLRQVNLGGTAVGTGLNASRRYIQLVAEKLRELTGFGLARAENLVEATQNTDIFAEVSGLVKTAAVNLAKIASDLRFLSSGPRAGIGEIRLPAVQVGSSIMPGKVNPVIPEMVTQVAIQVMANDVAISQACAWGNLELNPFLPLIAHNLLTSMEMLANAALILAERCVEGIEADWERCEELLHRSCGLITAFVPYIGYERAAEIVKEALGKEKRVEEVLLEKGLFTPEEIAAITSPQEVTTPGIAGIRY------
>UniRef50_UPI0001C16C0E(1-461:468) Fumarate lyase n=2 Tax=Nostocaceae RepID=UPI0001C16C0E   E=1e-122 s/c=0.96 id=48% cov=96%
MSNiDFRIERDSMGDRQIPNNVYYGIQTQRALENFPISG--IKPLASYVDACLYIKKATAIVNGELSCIPLDISKAIVQATDEIL-GGKLRDQFVVDVYQAGAGTSHHMNINEVLANRALEILGDEKGNYQRVSPNDHVNYGQSTNDVIPTAIRLgGLLALTQTLHPVLEKAIATLEAKAVEFQHIVKSGRTHLQDAVPVRLGENFRAWSHILSEHQNRIYTASGDLMVLGLGGSAAGTGMNTHPEYRKRVVEVLSQLLEIPLEPAPHLMAVMQSMGAFVNTSGAVRNLAQDMVKISHDLRLMDSGPKTGFKEIQLPPVQPGSSIMPGKYNPVMAEMTSMVCFQVMGYDQAIALAAQAGQLELNVMMPLIAYNLIHSIEILGNTIRALTDNCIQGIIANRERCLGYAEGSLALVTALNTHIGYLNAAAVAKESLETGKSLRQIVLERGLMTEEQLALVLDLEQM----------------
>UniRef50_B1I0U7(10-481:484) Fumarate lyase n=21 Tax=Bacteria RepID=B1I0U7_DESAP   E=1e-120 s/c=0.92 id=46% cov=99%
---DTRTEKDPLGEVAVPREAYYGVHTWRARENFAVSGLAVH--PELIRALALVKKAAAMANVEAGLLDDRRGAAISRAAEE-LAEGRWRDQIIVDALQGGAGTSTNMNVNEVIANRAIELLGGEKGDYGIVHPLDHVNLGQSTNDVYPTALRIAAIGLGRGLAQAMAVLQGALQAKEKEFGAILKIGRTQLQEAVPVTLGQEFGAWAEAVARDWWRLYKAEERLRQVNLGGTAVGTGLNADRRYAYRVVEILRELTGFGLARAENTFEATQNADIFAEVSGFLKAAAVNLAKISADLRLLASGPRAGLGEIKLPPVQAGSSIMPGKYNPVVPEMVTQTAFQVMANDLAVSLAAASGQLELNAFLPLIAHNLLQSFTILTGAAGTLAEKCIRGITADPERCRRLLDTSQGVITAFVPYLGYEQAAAVVERAIRTQRPLTEILVEEGLFTLEEVEAIMRPEELTTPGVAGARYFQRQKR
>UniRef50_Q7UNE6(71-543:543) Fumarate hydratase FumC n=4 Tax=Planctomycetaceae RepID=Q7UNE6_RHOBA  E=1e-117 s/c=0.90 id=37% cov=97%
---DFRTERDSMGEVRVPQNAYYGAQTQRAVENFPVSGWQL--PPSMIAAMGRVKLACGIANRDLGKltgsgknpLSDGQVESMLSAAKEVA-EGQLADQFPVDVFQTGSGTSSNMNINEVLSNRAIEIDGGDRmAEEKSIHPNDHINMGQSTNDTFPTAIHVAAAYEIEnRLLPALRRMHESLTEKAQAWDKIIKIGRTHLMDATPLRLGQEFGGFARQIELSIARAEAARDAVLELPVGGTAVGSGINTHPEFGARVAASLSEQTGIAFIEAVNHFEGNANRDGLVDSHGGLKCVAQTLLGLANNIRWLGSGPRCGFYEVKLPTRQPGSSIMPGKVNPVMCESLMQVAARVIGNDTCMTVSGGcGGNFQLNIMMPVMAHTILESIELLAGGVTAFIDFCLDGMEPNEEACEASVEQSLSMCTSLNPLIGYEQAAALAKEAFKSGQTIRELCKEKGILADDVLTEALDPWKMTEPQA-----------
>UniRef50_D2L8A8(1-465:499) Fumarate lyase n=1 Tax=Desulfovibrio sp. FW1012B RepID=D2L8A8_9DELT   E=1e-117 s/c=0.91 id=43% cov=97%
----MRQESDALGAKPLPEGALYGIHTLRAVENFPVSGQRLF--PEFLRAFALVKAACALANQETGHLDALRAEAIVAACREVA-DGRHDAQFPVDPFQGGAGTSTNMNVNEVVANRALELLGRAPGDYAFLSPLGHVNLHQSTNDTFPTALRVAALWLLKDLEAETARLQEAFQTKEAAFAHVVKVGRTELMDAVPLTLGMEFGAFAEALSRDRWRIFKCRERIKQVPLGGTAIGTGLGAPRDFIFRAAEHLRTLTGLPVSRAENLIDATANADPFVEVSGILSAFAANLLKISSDLRLLASGPATGIGEITLPALQAGSSIMPGKVNPVIPECVGQVALRVMANHQALTLAAGLGQLQINQFMPLLAHSLLESLRLLVQAARLFTDKCLAGITAGEARCRELVEKSHALATVLVPALGYAAVSRLLAEADAAGRPLAEHLAAKGMLAPEDAAALLAPKRMRKLGYETQDY------
>UniRef50_C8W2Y3(2-474:488) Fumarate lyase n=3 Tax=Clostridia RepID=C8W2Y3_DESAS   E=1e-112 s/c=0.86 id=43% cov=97%
---NYRVEKDLLGELKLPRAAYYGINSLRASQNFAVSGYGVNKH--LLRALAEVKLAAAQANLQASLLPAETARAICSAAQEVAEGG-LAEQFIVDALQGGAGTSTNMNMNEVLANRAIELLGGQKGDYDLVHPLNKVNLSQSTNDTYPTALRIAAIRLVLDLSEALAELQTSLQEKEAQFAGILKLGRTELQDALPITLGQEFGAFAEAIARDRWRLYKVEERLRQINLGGTAIGTGLNAPRRYIYQVVEELRQITGLGLARAENMVDLTQNADIFAEVSGLVKAAAVNLCKIAGDLMLLAAGPAGGLAEINLPPRQAGSSIMPGKVNPVILEAVIQVSWQVMGADQTICQACAGGRLELNAFLPLIAHNLLHVLEMLAKTARVLNSECIRGITANEERCRRWLEESNVLVTALVPYIGYEQATSLAQQAREENKTIVELVQARNLLTIEECQIIAAPRELTRPGIAGAR-------
>UniRef50_B7GJB1(5-432:449) Aspartate ammonia-lyase n=1 Tax=Anoxybacillus flavithermus WK1 RepID=B7GJB1_ANOFW  E=1e-100 s/c=0.86 id=37% cov=89%
-----RIEEDFIGKMEIPADALYGIHTARTVQNISFSGKKLFQYPEYIHALAFVKKAAALANVEAGLLSVAIKEAIVWACDEILDN-RYHESFVIDVLHGGGGIGTNMNMNEVIANLANEKLGGRRGTYHPVHHTEHVNRSQSTSDVCHTANRIAVILSFQSLGKQLEMCIQVMNELSKKFNHVETMSRTCLQDAMKVRVGESFRSYAAMLKRRLHWLSVSVNCLYQINLGGTVIGSGVGAPQHYRDVVVQKLCEVSNLPLQHRENLFDAAQHIDDLAAVSKELHLLASCLIKVAKDLRLRSSGPEGGFGEIVLPAVQAGSSFFPGKINPIVPETMIQCCFQVLGCDRVVQATLEHGELDLNVFEGIACINILDAMKMLERALASFIENCLLGIEVNEQRCKQLANSLIPAIVELKEKFGYSTVARWMKE------------------------------------------------
>UniRef50_A7HJN0(2-458:459) Fumarate lyase n=4 Tax=Thermotogaceae RepID=A7HJN0_FERNB   E=1e-97 s/c=0.79 id=40% cov=96%
---NCRTEKDYLGECLIPEDAYYGVTTQRALELFPSTGEILDD--KFIWAYFMIKKSAAILNSQLGYLDNQIAQAIQKACDE---WEKLKSYIVVDPLSGGAGTSVNLNINEVIANRATELLGGKKGEY-IVNPYNHVNLHQSTNDTFVTAGKIAVIVRLRELVEAVIKLQEKIQEKEKEFYSIRTIARTQLMDGVPILMGQQFGAWADALARDRWRLNKVEERIRSVNIGGTAIGTGIGAPKEYVLKIVDVLRQVTNVKIAKSENLIDATQNLDVFVEIHGLIKALGVNLFKISNDIRLLGSGPNAAIGELELPKVQIGSSIMPGKVNPVIPEYVMQLVLAVFGHDEAISHATAQGNLQLNQFAPLIVHYTLKSMQFLSKACNSLSDY-IAQIKVKEEKCKEHLKKSTANLTPLINYFGYERVAEkIVETNWDIEKAIELLAKEEG-ISSQELVKKLNIDKMTGLGY-----------
>UniRef50_B6WBB2(3-392:410) Putative uncharacterized protein n=1 Tax=Anaerococcus hydrogenalis DSM 7454 RepID=B6WBB2_9FIRM  E=3e-97 s/c=0.92 id=38% cov=82%
----FRQEEDSLGIVNVPADHFWGAQTERSLENFPQEVEKMPHSQ--IMAIASIKRCAAIVNNREEKLDDKKKDLIVDACDRILK-GEFDEEFPLTVWQTGSGTQTNMNVNEVISHIANE-------NEKIIHPNDHVNMSQSSNDVFPTAMHLSTYKNLsDKLLKELPKTIEAIKKLEEDNKDIIKTGRTHLQDATPVKLSQEISAWRTCLERDLKVLEEVKEELTYLAIGGTAVGTGINAEKEFGDEMAKELSELYEFEFKSDENKFYQLSSKSALVNVHGTIKALATDLYKIANDIRFLSCGPRCGISELTIPANEPGSSIMPGKVNPTQVESITMICIKIMANDFAISMANTQGQLQLNAYMPLIIHSMDNSITLLSKSLKCFREKLLEGLVANEKNIEK---------------------------------------------------------------------------
>UniRef50_B4MKH2(1-446:455) GK17051 n=1 Tax=Drosophila willistoni RepID=B4MKH2_DROWI   E=2e-92 s/c=0.77 id=30% cov=93%
MENHRRkLERDALGSLEVPNDRYFGAQTMRSSLQYHIGGQEERVPRAVIQAMGIVKKAAAEVSQEFG-LDPEISSSIAKAADEVITGQLYDEgHFPLHIWQSGSGAQTNMNVNEVISARANEIMG---GTQDPVHLYDHVNNLHSSNDTYPTAIHIAVgIELTHRLKPALTLLHDSVKAKSTGCNKIIMMGHIKtTKDAGPTTLSQNFSDYAHQLSNCLERLEAVLPRVWQLRMGETTAGTGHSIRKGFAGKCIERIAQITSLPFAKTANFMESLGARDAMVEVHGALNTIAASIMKIANGVRFLCLDPRNGLSE-----TEGGS---PG--NLSHCEVLTMICVQVMGNHVAVTIGGNNGHFELNAFKPLVASNVLRSIKLLTDGCISFNDNCLRAINDNKENVAKMMGDSLMLASTLEPHVGFERACQLAASALMNGTTLKDECLRIG-ISETQINDWL---------------------
>UniRef50_O66856(13-421:437) Adenylosuccinate lyase n=361 Tax=cellular organisms RepID=PUR8_AQUAE  E=6e-88 s/c=0.80 id=22% cov=67%
----------------------------------------------------------------------------------------------------------------------------------------YIHMGLTSSDVVDTALALLIREAIDIILKDIDKVMEEIKRLAFEHKDTLMMGRTHGVHAEPYTFGLKMCVWYDEMRRQKERLLFARENVLY-GKISGAVGTYSNIPPE----VEKLALEELGLKIEPASTQIV---HRDRHAQLLTTLGLIASSLEKFATEIRHLQRTEVLEVLE-PFTKGQRGSSAMPHKKNPIHSERICGLA-RVIRANSIPAMEDVVLWHERDISHSSVERVILPDSFIALDYILNLFYEILKGLVVNKERMRKNMELSKGlyasskiLVLLTQKGLSRDYAYDIVQRcamkAWESDKTFKETLLEDpevtKYLTEEEIEKALDPWEFL---------------
>UniRef50_Q5LZ30(12-434:449) Adenylosuccinate lyase, putative n=1 Tax=Streptococcus thermophilus CNRZ1066 RepID=Q5LZ30_STRT1  E=3e-85 s/c=0.75 id=17% cov=81%
-----------------------------------------------------VEAALAKIEGDLGIIPKSAADKIVEKAK--------VDNFDFLSLQKESAEKRHSLI----------ALIHALQEEVGGKEGEFVHYGVTTQDIVDTGIMLQTKEAYNIILDHTKDLISTLAKLTKEHRSTLMIGRTHGIHAIPITFGFKLSIWLDELLRSQRRLKQLLENDVFVGSISGAVGSYASFF-GRGREVEKAVLKELGLAVPNISWQ----PSRDRFSEFASVLGIFSGTLGKIGRELFTLMKTEIDEVHE-PFKKGEVGSSTMPQKRNPALIEGLASLTQPVFK-DVDLMFQSLLIDGERDAIHWRNEWVALPEITSYLDAQIVNATYILSGLKVNQDKMLDNLNKQGALpyseriMFEVGLKLGKQTAHEIVYQaamtALEENKDFIDLVYSDERVrlnfTKEDILSWVDPKNNIG--------------
>UniRef50_Q58201(24-429:484) Argininosuccinate lyase n=3 Tax=Methanocaldococcus RepID=ARLY_METJA   E=5e-85 s/c=0.78 id=22% cov=65%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNDEVATDLRIALREKVLIIAKSLIKMLKDILELAEKHKETLIVGYTHLQHAQPVTFAHHLLSYVSAIERDILRLLDAYKRINISPLGCGAMATT------GFKINRERTKELLGFD-ALIENSMDGVSARDFILETMADLAILGTNLSKICEELILFSTYEFGTIE--IANEFCSTSSIMPQKKNPDVAEIARAKLSKLNGNLVTALTILKALPNTYNRDLQEISPHLWDSVYTTIDTIK-MVHGMLKTIKINKERMEELAKANYSTATELADTLVRETgipfrtahgiVGEVVRRSIEEKKDMIEVIYEvlekyNLKVDEEKIKKALDP-------------------
>UniRef50_Q0AGL1(43-432:461) Argininosuccinate lyase n=9 Tax=Bacteria RepID=ARLY_NITEC   E=9e-85 s/c=0.81 id=20% cov=65%
------------------------------------------------------------------------------------------------------------------------------------------HTARSRNDQVATDIRLYLRAAIDEIIDLIYGLQYVLLDLAEQHAATIMPGFTHLQVAQPVSFGHHLLAYYEMLLRDGQRLQDCRKRVNQLPLGAAALaGTSYPIDR-------EQVARELGFD-DICHNSLDAVSDRDFAIEFCASAALIMMHLSRLSEELILWMSPA---FGFIRIaDRFCTGSSIMPQKKNPDVPELVRGKTGRINGHLVALLTLMKSQPLAYNKDNQEDKEPLFDTVDTLKDTLTIYAD-MLAGLQVNPQAMRQAALRGYATATDLADYLvkkgtpfrdAHETVAQAVRFAENKRCDLGELSLADlqqfSAIIEQDVFEVLTLE------------------
>UniRef50_Q0TTA6(2-417:466) Argininosuccinate lyase n=69 Tax=Bacteria RepID=ARLY_CLOP1   E=1e-82 s/c=0.74 id=23% cov=52%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNDQVTLDTKLYLKGYIKILICEILNLEKTLLNLSSENKETIMPGYTHMQKAQPITFAHHILAYSEMFKRDISRLLDCYKRLDEMPLGSGALATTT------YPINREKVANLLGFSKVTL-NSLDSVSDRDYAIETLSCLSLLMMHLSRFSEEIIIWSTD---EFKFIELDDsYSTGSSIMPQKKNPDVAELVRGKTGRVYGDLMTLLTVMKGLPLAYNKDMQEDKEALFDGLDTTLLSIKTF-NGMIKTMKINK--------------------------------------------------------------------------------
>UniRef50_A4W487(3-428:464) Argininosuccinate lyase n=23 Tax=Bacteria RepID=ARLY_STRS2   E=4e-81 s/c=0.71 id=22% cov=61%
--------------------------------------------------------------------------------------------------------------NEDIHMNIESLLTEKIGS-----VAGKLHTARSRNDQVATDMHLYLKDTLFQVVDKLTNLRQILVDLAQEHVETIMPGYTHLQHAQPISFAQHLLAYYNMFSRDSERFAFNMQHTNVSPLGAAALaGTTFPIDRQMT-------SDLMGFA-KPYSNSLDAVSDRDFILEFLSNASILMMHMSRLCEEIINWCSY---EYQFVTLsDTFSTGSSIMPQKKNPDMAELIRGKTGRVYGNLVGLLTVMKSLPLTYNKDLQEDKEGMFDTAETVLISIDILA-GMLKTMTVHKERMAQSTEKDFSNATELADYL-----------------------------------------------------------
>UniRef50_A9H6Y6(20-437:473) Fumarate lyase n=7 Tax=cellular organisms RepID=A9H6Y6_GLUDA   E=8e-79 s/c=0.71 id=18% cov=81%
--------------------------------------------------YLAVEAALSEVQGRLGIIPADAAKKIASVC--------LLEKIDMVRLADETAEIGYPVLPLVHQI-----------QSLAGDAGDWCHWGATTQDITDTATVLQIKASLDVVADLLERCIAAASGLARAHRDLPMVGRSNLQQAVPITFGFKMARLAACLLRHRERLAELRPRIEVLEFGG-ACGT-LASLGDRGLDVQKVLADTLGLARPPITWHTD----RDSIAETACFLGLVTGTLSKFATDLKTMMMTEVNEAAEPFVL-NRGSSSTMPQKRNPISCCYITACAASV-RQSTAALLGSMDADHERATGPWEIEWIELPRIFSLASGALSQAAFVIEGLEVNGDRMAANLGITKGLimseavMMALAPKIGRGQAHdmlyKVCRAALEQNRSLAEMLKADDAVTEQlshrQIDHLTDPARYLG--------------
>UniRef50_B4U6T9(13-415:458) Argininosuccinate lyase n=3 Tax=Aquificaceae RepID=ARLY_HYDS0   E=2e-77 s/c=0.72 id=23% cov=41%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNDQVNTDLRLYLKDHILKIFELLKALKQQLVLKAKEYEDLIMPGYTHLQRAQPVLVAHYLLSFKEAFLRDSQRLIDAYRRIDTLTLGSGALaGADFPLDRFLE-------ASILNFS-KISRNSMDAVADRDFAIEYMFCLSSIAMHLSRMAEDFIIFNTE---EFKFIDLPDSlCTGSSIMPQKKNPDVLELIRGKAGRVYAN------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q1LG43(48-473:490) 3-carboxy-cis,cis-muconate cycloisomerase n=69 Tax=Bacteria RepID=Q1LG43_RALME  E=2e-72 s/c=0.65 id=18% cov=83%
-----------------------------------------------VRRMLDAEAALARAEAQCGVIPATAAAVITEVCGRV-------DVIDLEALAQAAVSAGNLAIPFVKQLTAAV-------TQRDADAGRYVHWGATSQDIIDTALVLQLRDALREIVVDLLRAGDACATLAATHRATPMVARTWLQHALPTTFGCKAGGWLDALRRDLTRLDHVGAQVRVIQFGGAA-GT-LASLGDDAPAVAARFAAELQLDVPALPWH----AHRDRLVEVATALGMLTGTLGKMARDVSLMMQTEVGEVAEPSGPGR-GGSSTMPHKRNPVGCAAVLTAATRVPP-LVATMLAGMTQEHERALGGWQAEWDTLPQIVTLAAGALRQMADVASGLEVDEARMRANLDITHGLilgeatMLELGRRIGRLQAHHLVEQASRRaaaedttlrialARTLAEDANHAGLLDDAALDRLSDPAQYAG--------------
>UniRef50_D2R2G4(14-419:476) Argininosuccinate lyase n=1 Tax=Pirellula staleyi DSM 6068 RepID=D2R2G4_9PLAN  E=5e-72 s/c=0.67 id=24% cov=56%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNDQVSTDLRLWVRDALDRVDGLLANLQRAFVGRCDADFDVILPGYTHLQRAQPVLAPHYWLAYAEKFARDRARVADCRKRTNICSLGVAALaGTTLPIDRF-------ETARLLGFD-EVAANSLDVSSDRDFVLESAFVLSMISAHLSTWAEEWILWST---AEFNFLKLPhDFCTGSSIMPQKINPDVLELTRGKTGRVIGNLQTLLVLIKGLPLAYNRDLQEDKPAIFDSFDTVEI-CLELAAPLVAGATLLRDSINERLDRGHLDATTL---------------------------------------------------------------
>UniRef50_B3T6G2(5-436:449) Putative Lyase n=2 Tax=root RepID=B3T6G2_9ZZZZ   E=8e-72 s/c=0.63 id=17% cov=81%
-----------------------------------------------------VERALVWAHCQLGRVSAEDYDKIADIAD--------------------PGIVTADRVDEIEQETRHDIMALTKAMAEAAGEAGWcIHLGATSNDIVDSAVALQIKDSIAMQRDMLKQLITTMCDIAERERDTVMLGRTHGQAAVPITFGLKVAVWVDEFARHLERLDELATRATTGKFLG-AVGTG-AAQGEDAFELQDLIMTELGLGIPVATTQVVG---RDRYIEWVGWMANVATSVEKVLQEVRNLQRSEIAEVAEAFDAEKQVGSSTMAHKRNPITSENACGLA-RIVRAMIVPSYENALLWHERDLANSSAERFTLSHSMILLDDILAKSDWVLSNLVVDSQRMRANIDAQQGLVMAecvmlalVDKGVPREDAHEILRRASTEtlssGVNLEEVCSKIPLISDafgsAELRSLFEPEGYLG--------------
>UniRef50_UPI0001C3166B(30-446:452) argininosuccinate lyase n=1 Tax=Conexibacter woesei DSM 14684 RepID=UPI0001C3166B  E=1e-70 s/c=0.65 id=22% cov=67%
------------------------------------------------------------------------------------------------------------------------------------------HTARSRNDQVATDMALFTRAHAQAAQEAIRGLMRALVATAERHLDWRMPGYTHLQRAQPVYLSHHLLAYVWMLARDLEKFAAVEQATARLPLGAGALA-GVNFDTD-----RQLVARELGFAGV-AENSIDAVSNRDFVLDYLAAAATCGTHLSRLGAEIVLWSSSEFA-FAEVS-DAWASGSSIMPQKKNPDAAELLRAKAPRIAGHFVALQGTMHALPLTYNKDMQEDKEHLFDAVDTLEL-CLAAAAGMIEGIAFDRERMAEAASDEFPAATDVADLLVRRgmpfrechgVVAGLVKQAVDSGRTLTELTLteirEQSELLDGEYYEVLRGERWLES-------------
>UniRef50_Q13PC6(15-432:445) Putative lyase n=1 Tax=Burkholderia xenovorans LB400 RepID=Q13PC6_BURXL  E=6e-68 s/c=0.62 id=17% cov=81%
--------------------------------------------------YLKIEVALAKVEAGLGVIPQDAWRDIEQKSHSFEIDW---ERFRIDV------EAVGYPVMPFVTQLAE----------HCGESGEYLHWGSTTRDITDTSFVLQLREALGVLAADLDKVRRKLREMTARHRSTLMIARTHGKHALPSTFGFRCAVWYSEVERQCERLAALRAE-PFVGQFGGAIGTLAAVGPR-GLEVQSALMAELGLGTAE----IAWFASRDRVSEVVFRIASIAQSMASIAKSLVIMTRDELAEASEGG-GEQRGTSSAMPHKHNTVVPELVI-VHGKMATQQVAIVMESMVQDFERD-WQGHFETIAVPQTFQHAHAAVTQMHTVLSGLILHEDRMRANLDVTrgqvmaESVMMALAPKLGRKNAHhaisRLCNQALAEDRPLGEVLRADPqvaqYLGEHELADALDPAGYIGLA------------
>UniRef50_O29379(22-425:483) Argininosuccinate lyase n=2 Tax=Archaeoglobaceae RepID=ARLY_ARCFU   E=2e-67 s/c=0.64 id=23% cov=65%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNDEVATCLRMFARDHLLNLAEAILNALDVLIKKAEK-SHFLMPGFTHLQYAQPTRLSHHLLAYHDMLSRDFERAIEAFRRVNKSPLGSAAfASTGYSLDRVYA-------ARLLGFDGV-VEHSEDAVASRDFVIESIFVAAEAMLSISRIAEEIVLFSS----EFGFITLPdEFSSTSSIMPQKKNPDIAELLRANAGKIAGNLTSAMMIYKATPFSYNRDFQEMNPLLYESLKRTHLAVEVFAS-MMGKIKFNPEITERKASKGFATATELADMLvmkygvPFRMAHRIVGRLAAkelerpTASDVNSAAKELGVeinVRDEDVLEALDVEKVVE--------------
>UniRef50_C3MHA8(15-430:445) Adenylosuccinate lyase n=1 Tax=Rhizobium sp. NGR234 RepID=C3MHA8_RHISN  E=6e-67 s/c=0.62 id=20% cov=81%
------------------------------------------------QAWLDVEAALALAQAKLVLIPPEPAERIAACCD--------AKGFDYERLSKEIAFAQHPFVP----------VLKQLEELCGEPAAGFIHWGATTQNIFDTAIALQLKKTHLHLIAVLERTEERLKGLAFEHRQTLQAGRTHGQHALPMTFGFKVAGWHEEIRRSRERL-AARGKTSFLAYFGGAIGTFAAMD-GKGRAVEDEAARLLGLQPARLP----LRSSFDRVTDYLAALAVLAGSIHKIAQDIVFMQRSEIGEIEE-AFHMGKVGSSTMAQKRNPSAALVLVSLCRMLEGRLPMVL-AAMVRMDEGDSSATNIADIVVGEIAVLAASIAEGADRVLSGLHVNAEKMRRNLDLSRGLilsesaMMQLSPRIGRHKAHHLLYEAaqrtAMEGTAFSQTLadaMKDAGLADVELD--LSPDDYLG--------------
>UniRef50_D0U661(72-417:475) Argininosuccinate lyase n=1 Tax=uncultured actinobacterium RepID=D0U661_9ACTN  E=2e-64 s/c=0.72 id=23% cov=48%
--------------------------------------------------------------------------------------------------------------------------------------------GRSRNDQVTTDLRLFSIDHMLEVAHLITLLQTAILEKASEYVNDPAPGFTHIQHAQPVSFGHELAKHAHAFARDLDRINDWLARTSVSSLGAGALaGSSLALEPAFT-------AQNLGFDSSFA-NSIDAVSDRDYVAEALFICAMIGSHLSRIGEEWTLWASQEFAWAK--VADAYSTGSSIMPQKKNPDMAEIARGKSGRLVGNLMSVLTMLKGLPFAYNRDLQEDKEPLFDSIDTL---------------------------------------------------------------------------------------------------
>UniRef50_B5Y8W3(11-415:432) Adenylosuccinate lyase n=1 Tax=Coprothermobacter proteolyticus DSM 5265 RepID=B5Y8W3_COPPD  E=3e-63 s/c=0.60 id=19% cov=66%
------------------------------------------------------------------------------------------------------------------------------------------HRGLTSSDIMDTVFSLQIKQSLRHINALTDETIKVLTEKADQFKHNACAGRTHGVHAEPYFFGLRFLTVAVALKRSLNMLAALEQSIP--GKLSGALGIYTNLDPD----IESEFLRILGLSALPVSTQIVP---RDVYAPVLFYLALEASILDKLAQDMRILQITEIGEAQE-EFKRGQAGSSAMPHKRNPVRWERISGLS-RVLRSQVNVALENVSLWFERDISHSSTERIVYPLCFDLIAFMLKETKSLVSNSVFDSSRMLANMSNSKNLlyssraLSLIQQKLGREAAYKRVQDLSRqvldgEAEDFIEALRSSGLLSEEELQSITDVSDL----------------
>UniRef50_A8IK84(46-447:504) Argininosuccinate lyase n=4 Tax=Proteobacteria RepID=A8IK84_AZOC5   E=3e-62 s/c=0.60 id=25% cov=65%
------------------------------------------------------------------------------------------------------------------------------------------HTARSRNDILATMDRMRCRDLVIALLDALAELRQTAAEQAARYVDVVMPGYTHLQPAQPMTYGFYLAGVAEALERDAERLAGAYGRVDRCPLGAGAfAGTPYGIDRS-------ETARLLGFPAVVDST-LDAVASRDFIFEVLGSLSILAATWSRIAQDYFLWSTD---EFRFIEFPDSVAGtSSIMPQKKNPIVLEFLKGKAGHIIGHYAGAVSILRATNFTHSGDANRESISFFWGAADDCLTSLKLLRLIIRTASPRREVMLKRARENFSSATDLADAIvmksglsfrqAHHIVGAVVRDALDHDLTAdrisldmvqracRDQMGREIALSEEDVHASLDPR------------------
>UniRef50_Q12CF4(18-387:419) 3-carboxy-cis,cis-muconate cycloisomerase n=3 Tax=Comamonadaceae RepID=Q12CF4_POLSJ  E=3e-60 s/c=0.64 id=21% cov=56%
----------------------------------------------FLDAMLRFEGSLARAQASVGLIPEAVAQSISGTCK--------VELFDVAKIVRESGRAGS------IAIPLVKSLKETVGLFNK-DAAGFVHFGSTSQDVIDTALALVTRNALNLIEADVHKAVAALLVLAGRHAADPVLARTLMQPASVTSFGLKCAGWAAPLVRSLQRLQATAGNALSVQLGG-AVGTLAQMQKAgknLGPQVIAHMASELKLR----APSCAWHTQRDEWVALGCELGLLVGSLGKIAKDIALMGQYEVGEVAEPTEPGR-GGSSAMPHKRNPVACMVA----------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q05911(40-456:482) Adenylosuccinate lyase n=68 Tax=cellular organisms RepID=PUR8_YEAST   E=7e-58 s/c=0.54 id=19% cov=62%
------------------------------------------------------------------------------------------------------------------------------------------------------------------IIPKLVNVINRLAKFAMEYKDLPVLGWTHFQPAQLTTLGKRATLWIQELLWDLRNFERARNDIGLRGVKGTT-GTQasflalFHGNHDKVEALDERVTELLGFDK--VYPVTGQTYSRKIDIDVLAPLSSFAATAHKMATDIRLLANLKEV---EEPFEKSQIGSSAMAYKRNPMRCERVCSLARHLGSLFSDAVQTASVQWFERTLDDSAIRRISLPSAFLTADILLSTLLNISSGLVVYPKVIERRIKGELPFMATENIIMAmveknasRQEVHERIRvlshQAAavvkEEGGenDLIERVKRDEFFKPiwEELDSLLEPSTFVG--------------
>UniRef50_B0U0M0(4-393:397) Argininosuccinate lyase n=2 Tax=Francisella philomiragia RepID=B0U0M0_FRAP2  E=1e-53 s/c=0.55 id=23% cov=40%
-----------------------------------------------------------------------------------------------------------------------------------------IHTGRSRNDQSLVMLRLFMIDKIQFLEKTIQENIYTLRSKASKFKNIPMPGYTHMQKAMPTTVATWLGSFADALADTLLLISATSKVINQNPLGS-ASGFGISNFKHDKEY----TTELLGFNRTQDNPIYCACSRGYFEKLALQTFSNPISIYSRFANDMMLFTMAEFDYFSLSN--SYTTGSSIMPQKRNYDLFEIM----------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_UPI0001692E4A(1-236:241) aspartate ammonia-lyase n=1 Tax=Paenibacillus larvae subsp. larvae BRL-230010 RepID=UPI0001692E4A  E=4e-52 s/c=0.88 id=41% cov=50%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDDLLEIGIGGNAVGTGIHTHPKYAELMTEEIARRTGRPFRSTANRFAFMQNPSAALRVSGLLREIAVHLIKMTSDLRLLNSGLHTGLAEINLPAVQPGSSIMPGKVNPVLPEMTYMVCSQVIGNDTAIQTAMIGGQLEINVMMPVIAHNVLFSISILSRTMKSLSTKCLKGIEANREQSRWWMEQSLSLVTLLNPVIGYDHASRLAKQSLQERKPLKEVVLASGVINEVEWNQLV---------------------
>UniRef50_B2AVP6(10-488:523) Predicted CDS Pa_7_2220 n=12 Tax=Fungi/Metazoa group RepID=B2AVP6_PODAN  E=8e-51 s/c=0.42 id=20% cov=72%
----------------------------------------------------------AEAERELGLpIPEDAIQEMrenVRVSDEAFDKAREYEaKFRHDVMahvhaygevsnsrgEGGRGkgddvNGGRYRMRQRLLDISIWGLRVVMVSFDFCSFGwGWMWLG--RWNMTDNADLIFQKKALDLILPKLAKVIQNLQVFALKYKDLPTLGFTHYQPAQLITVGKRAAQWIQELMMDLEDIETVRDRLQFRGAQGTTgsQATFLELFEGNADKIVqlnEILCKKAGFP--SAYPISTQTYTRKVDLRVANAVCALGATAQRICSDIRHLANLKEM---EEPFEKSQIGSSAMAYKRNPMRSERITALGRKLARLPADFTATFETQWFERTLDDSAIRRMDIPEMFLLADSILLALDNVTNGIVLYPSVIRSRIDQ-----------------------------------------------------------------------
>UniRef50_Q981V0(458-867:927) Argininosuccinate lyase 2 n=3 Tax=Mesorhizobium loti RepID=ARLY2_RHILO  E=1e-50 s/c=0.50 id=18% cov=49%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------QGALLQRVEEASSLVAPLYSQYQIALPGSPGHYLLGVFFALGRERQRLHSLLEDIRNCPMGAGAgGGTSMPIDPL-------KTASLLGFE-EPSFNSLDAVASRDHHLHGLSIFASISTLLSRVAQDLQVWTT---REFALIDVPRNlAGGSSMLPQKKNPFLLEHIKGSASTVIGAYVSAATATCKAPFSNSIEVSNYGCSPLRLSEEALQRALILTSLIVKGMSFNVRSMRDHLEDGSS-MTAIA--------------------------------------------------------------
>UniRef50_B9P6D5(259-646:702) Predicted protein n=1 Tax=Populus trichocarpa RepID=B9P6D5_POPTR   E=2e-50 s/c=0.52 id=21% cov=38%
--------------------------------------------------------------------------------------------------------------------------------------------GATTQDAVDTAQALLTQQALQALLAELGALQCALQALARTHAATPMLARSLLQPAQITSFGFKCAQSAAAVGRSIEQFERLATAALCVQLGG-AVGNG-AVLGSHRAEVEQALARRMGLSACGRSWH----TQRDDWMRLAMEAAVCGGSLAKLAKDWSLMSQYEVGEVSEAP---RGSTSSAMPHKRNPV---------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C0WN00(15-432:466) 3-carboxy-cis,cis-muconate cycloisomerase n=3 Tax=Lactobacillus RepID=C0WN00_LACBU  E=4e-50 s/c=0.48 id=13% cov=59%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------LYDLADKYKKTINVAMAHRTYSSPSTLGFKLGIILNELDYLMRRLDSLSDFTFAGSLTGV---EGLSTMvGDNYDQVETDFCDYLDLQVPE----MYWHTQRERFTEYCHVLTMIAQMLGKLGKDLLTMSQTQVGEFQEAYAPGRQ-GSTVIPTVREPYMCEAIVNLST-IIRNEMPLMYDTMQVSGEKDTAVWRDIYVVLPEMTMYLSGQLNYATTILKTGKFDTKRMAENFilgdgtMYSGALMMALAkKGMGRQDAHElLVRlrvKADEENKLLKDLFYSDdtiaKYLSRQDLDKVMSPEA-----------------
>UniRef50_Q28RT3(22-403:438) 3-carboxy-ciscis-muconate cycloisomerase n=7 Tax=Rhodobacterales RepID=Q28RT3_JANSC  E=3e-48 s/c=0.51 id=20% cov=54%
-----------------------------------------------VRAMMLVLGALAKVQGAAGVIPEISGAFLHRATMEIQIDPM-----------GLAGANGVVVPGLVAAMR---------DALEAPEHAQYLHWGATSQDIQDTAQSLRLRQVLALMEGRLRDLLTVLTDLAEAHAETPQAARTYGQFAVPSSFGALVAGWGWPVIRLLERLPDLRDYALCVSL-SGAAGTASQLGPDPAALRAALAE-----ALGLSDPKQSWHADRARIIEIAGWLSGAAVAMGKIGEDVLRLSRSDVGEVR----IGGAGASSTMPQKQNPVAASAL----------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C1XGT7(79-419:487) Argininosuccinate lyase n=2 Tax=Meiothermus RepID=C1XGT7_MEIRU   E=2e-47 s/c=0.56 id=21% cov=65%
-------------------------------------------------------------------------------------------------------------------------------------------RGLSRNDLDLTVFRAYACERLLRVLTSLSDLRRELLGLGQNHRQTLLTAYTHHRPAQPTTLGHYLTGVENLLSRDYQRLRSAFQTTDKCPLGASTLaGSPYPVDR-------KALAQWLGFGGTL-EHTYDAIAAGDWALEIAYALAGMATSLSRLVADLLFWAEQG----GFLVAEKISQGSSIMPQKVNPVVLEHVRGFLAELMGGPTTLGHLNYSTPFgDVNDHGPGVLEP-LYNLFYAAEGAVALLRVALQESRFVPEVLAQGLRDRSVLASELVDVLvagkrlslaeAYPKVQGMLRELSSKGRTVAELGLDDLQshlgFGDPELLQALEPERFI---------------
>UniRef50_A8MCU5(22-391:450) Argininosuccinate lyase n=1 Tax=Caldivirga maquilingensis IC-167 RepID=A8MCU5_CALMQ  E=5e-47 s/c=0.52 id=25% cov=39%
-------------------------------------------------------------------------------------------------------------------------------------------LGRSRNDHVATALRLRLRKLIIELASSIIELRRVVLNKAIETADTVIIGTTHRQPAQVTTLGHYML-YLDELSRDfLTSLLSIYEVVNKSPLGSGPLaGTMVKLNRV-------REAEELAFNG-IVENTVYATGSRYFMLASASITVSYLVELGRFINNIEMWLMPQLNYI--TLEPSHLATSSIMPHKRNPATLEV-----------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D2Q9D5(18-479:484) PurB Adenylosuccinate lyase n=28 Tax=Actinobacteridae RepID=D2Q9D5_9BIFI  E=2e-46 s/c=0.41 id=18% cov=67%
-----------------------------------------------------------------------------------------------------------------------------------------VHFACTSEDINNLSIARCVKNGIENVwLPGAQAIVDHLAEKAEEYRDKAMLSLTHGQPATPTTLGKELAVYVYRLSRQLNKVRN-QEYLGKINGATGTFGAHLAACPDVDWVAVSRefVTNRMGLTWNPLTTQIE---SHDWQAELYGTISHTNRILHNLCVDVWMYIS--RGVFAQVPV-KGATGSSTMPHKVNPIRFENAEANLEISCSLLDTLSATLVESRWQRDLTDSTTQRNIGSALGYSVLALNNLMGG-LNSIHPNDIAIQAELDANWevlgepiqtaMRACELAGLPGMDKPYEKVKE-LMRGHEISQDAVER-FIDEQSFDEataarlkALTPATYTGVASR----------
>UniRef50_C3XBD5(11-475:475) Adenylosuccinate lyase n=2 Tax=Oxalobacter formigenes RepID=C3XBD5_OXAFO  E=2e-46 s/c=0.41 id=17% cov=54%
-----------------------------------------------------------------------------------------------------------------------------------------IHFACTSEDINNTSHGMMIKAARDEvVLPALNAVIEQLRSIAHQNASLSMLARTHGQTASPTTLGKEIANIVSRLQRAAGKIAA----VEIMGKMNGAVGNYNAHFSAYPDFDWENFSRnvvenSLGLTFNEYTIQIEP---HDYIAELFDAIARANTILIDLNRDIWSYIS---LGYFKQITKAGEVGSSTMPHKVNPIDFENSEGNLGMANALLKHMSEKLPISRWQRDLTDSTVLRNIGMALGYTVLAYDSCLRG-LNKLEVNAERITHDLED-----------------------------------------------------------------------
>UniRef50_A8M9J3(6-445:470) Adenylosuccinate lyase domain protein n=1 Tax=Caldivirga maquilingensis IC-167 RepID=A8M9J3_CALMQ  E=4e-46 s/c=0.43 id=17% cov=69%
-----------------------------------------------------------------------------------------------------------------------------------------IHLGLTSEDVNNLAMGIMIKRILyEYLIPSLVDLGKVLVNLSNKYADTPMLARTHGQPATPTTFGKEIAYHSHRLCSWISTLINLKINGKVAGASGSMASFTMIAQLDWPRELMNFVSS-LGLEPTPVATQILP---PDNLNHIIAAVGLTSYSLINLAQDMWMYSM-----LGYIKFKGRVIGSSTMPHKVNPVDLENAEGNLKLGASMLMEISKILQSSRLQRDLSDSTIKRNLGLAMGYVVLGSRRLRKFM-EGIEVNEEALTNDLNNHWEVLSEAVqvrlRVLGQANAYEkslkLFRVPRMSMSDYINAIKELGVNDELLLN--LRPSNYIGYASVIARNIAES--
>UniRef50_B2GIK4(14-419:490) 3-carboxy-cis,cis-muconate cycloisomerase n=1 Tax=Kocuria rhizophila DC2201 RepID=B2GIK4_KOCRD  E=9e-45 s/c=0.45 id=19% cov=76%
-------------------------------------------------AILAVEDAWVAAQHREGLVSAEEAAAAHAAVDRVGTDPHHLRELVTASEGGG--------------NPVIPVLGAYRRavEQVLGRPLPAVHASLTSQDVMDTALAHLLSSVRRRVVGDLTRAGDALAELVRRHRGTPMVARTLTQHALPTTFGLKAAGWLAAVDDAAD---EVSARVRLPLSCGGAAGTLAATvalvsgtapgaqssaqgaahdqPLDPTQRLLHHWAGQLGLEVPDAPWH----TTRTPVVRAAGALAEVAAALSRLANDVLLLSRPEIGELREPTAP-GRGASSAMPQKQNPVLSVLLKRTALLAPGLASGVLAGAGAAVDERPDGGWHAEWPALGELAELTAAASSHAAELAEGLTVDAPRMARNLADagtgvlAEPLAVALAPMLgerGADTARQLVRDAVR---------------------------------------------
>UniRef50_A3XE63(28-345:353) 3-carboxy-cis,cis-muconate cycloisomerase n=2 Tax=Rhodobacteraceae RepID=A3XE63_9RHOB  E=1e-44 s/c=0.58 id=28% cov=40%
-----------------------------------------------------------------------------------------------------------------------------------------IHTGATSQDVIDTAMVLTCLNVLDELEDRLATLVDRLETLLDASRDLPLMARTRMQAAVPATVGLRVSSWLRPLVDHQSRIQALRQDLAKVQVGG-AVG-KRDTPADHAELVAEHVAHALGLSLGPV-----WHTDRTSLVGFGHWLTLVSGSLGKIGQDIALMTQQ---GVDEIVLDGG-GGSSAMPHKQNPVLAEAI----------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_UPI0001B4D944(1-439:457) 3-carboxymuconate cycloisomerase PcaB n=1 Tax=Streptomyces viridochromogenes DSM 40736 RepID=UPI0001B4D944  E=1e-44 s/c=0.42 id=20% cov=68%
---------------------------------------------------------------------------------------------------------------------------------------EYVHRGSTSQDVLDTGAMLVAARTLRIIRADLGRAAEALAELAGTHRDTLMAGRTLAMHAVPTTFGVKAAGWRQLLLDADRRLELVLVALPVSLGGSagtlagyveyaridgrAAARSGGATDrddrdrgrdgdsgsdldvARYVAELTEAFGAETGLAAGPA---MPWHALRTPIADLAAALAFTAGALGKLAVDVQSLTRTEVGEVAEPSV-AGRGVSSAMPQKRNPVLATLVRSAALQVP-VLAAGLTQCLVTEDERSAGPWHAEWQLLRECLRLTGGAAHTAVELAAGLEVRPERMRQNVALigsalvSERLAAALAPRLGKAAAKRLLSMATElasgSGRPLPEVLAHLpelaGVFAPKELDRLCDPAGYTGAA------------
>UniRef50_UPI0001AF7079(17-373:409) PcaB n=2 Tax=Mycobacterium RepID=UPI0001AF7079   E=2e-44 s/c=0.51 id=19% cov=39%
-----------------------------------------------------------------------------------------------------------------------------------------IHRGLTSQDVLDTSLMLGMRSVADHVITQLAQQITTLSALAGAHRGTPMVARTLTQHAAPTTFGAKAAVWLNGVVDAYLRLGALVTPAQF----GGAVGTWSATtelaslltataePAELAERVIRSATTTLGLRVRLP-----WHTTRTPVTAAADALVGCTDCWGRIAADVITMVRPEIAELGEPAGGPR-GGSSSMPHKRNPV---------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q21774(41-409:478) Adenylosuccinate lyase n=3 Tax=Caenorhabditis RepID=PUR8_CAEEL   E=4e-44 s/c=0.49 id=20% cov=36%
---------------------------------------------------------------------------------------------------------------------------------------------------------IAYRDSIDHILKRFATVIDRLAAFSLKNKEVVTVGRTHYQTASLVTVGKRGVLWAQELLMAFQSLSEFRDKMRFRGIKG-ATGTQdsfltlFAGDESKVEALDELVTKKANFSNRFL--ITGQTYSRQQDSQLVFSLSLLGAAAKKVCTDIRVLQA--FGELLE-PFEKDQIGSSAMPYKKNP----------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A1RR78(22-416:429) Argininosuccinate lyase n=5 Tax=Thermoproteaceae RepID=ARLY_PYRIL   E=3e-43 s/c=0.45 id=25% cov=54%
--------------------------------------------------------------AEVGIMPKEAADAILKTLKEATPEQLLSSEF------------------EDIHEALEKWLIDRLGE----ETAGWVGLGRSRNDHVAAAIRLAALRKASALRKNVEKMRCILAKKALEYADCAMPSFTHFQPAQAITFGHYLLAVDELAAEFLHVLKAVEKLLKRSPLGAGpAGGTRTPIDR-------ERLAKLAGFEDV-VENALYASGSRFFALALASAVVSFLTELSRTVDDLIRWNSPLVGYVAAP--DSHVSTSSIMPHKRNLVTLEVFRARAAEALGHLTAL--------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A4JPB5(410-769:860) Argininosuccinate lyase n=2 Tax=Burkholderiales RepID=A4JPB5_BURVG   E=1e-41 s/c=0.48 id=27% cov=38%
--------------------------------------------------------------------------------------------------------------------------------------------ARSRNDINATHLLLTVRQALSHVTRRVVDLGETLARRAADSAEVLLPIYSQYQTAMPGSAGHYLVAQCEILLGTLDALASLRDGLGSSALGACAgAGTTFVTDP-------RRTAVLLGFSTGPL-NSLSAITDKNPALRCACLLTELSSNLNRIATDLQLWS---MREIAIVTLPDGmYGGSSNMPQKRNP----------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C0QI65(26-463:464) PurB n=1 Tax=Desulfobacterium autotrophicum HRM2 RepID=C0QI65_DESAH   E=1e-41 s/c=0.39 id=25% cov=33%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------LETLLKALEETGLKHKSVPMMGRTHGQPATPTTVGKEFINFAWRIRHELFILQGATVQAKIN----GATGNYNAHYFVYPEIDWisageRFLGQSLGLEPLLFTTQINPNASLSFILH---SLVRSAAIIIDFDRDMWGYIS---LGYFRQQLKAGETGSSTMPHKVNPIDFE------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_UPI000185BF09(40-425:476) adenylosuccinate lyase n=1 Tax=Corynebacterium amycolatum SK46 RepID=UPI000185BF09  E=1e-39 s/c=0.43 id=18% cov=63%
---------------------------------------------------------------------------------------------------------------------------------------EHIHKGMTSRDLTENVEQLQVLQSLKVVRDKAVAVAARTAEKASEYQSLVMAGRSHNVAAQATTLGKRFASAADEMLLGIERVEDLVSRYPLRGIKG-PMGTAqdmldlLDGDESALASLENEIAEGLGFDRV--FDSVGQVYPRTLDFDALSALVELGAGPASLATTIRLMAGNETVTEGF---KEGQVGSSAMPHKMNARSCERVHGFQVILRGYMTMISEYAGTQWNEGDVSCSVVRRVALPDAFFAMDGMFETFLTVLSEFGAFPAMIDRELERylpflasTKILMAAVRAGMGREEAHEIIKEhAVATALDMRE--------------------------------------
>UniRef50_D1S4X8(18-347:484) Argininosuccinate lyase n=1 Tax=Micromonospora aurantiaca ATCC 27029 RepID=D1S4X8_9ACTO  E=2e-35 s/c=0.46 id=26% cov=39%
-----------------------------------------------------------------------------------------------------------------------------------------VQLARSRNDLDAGVFRMVLRDQLLQVLDALLATGRTVLDRADRHADVVITGYTHRRPAQPTSIGHVFAGYAEALAGEAAAYAGLLDEMNRSPLGSCAfAGTDLDISP-------RRLADLLGFD-QLIVNSYEAVAGADHLVRVATLNAQALATGARLARTLMDWLSWGWV----VTPGEFTQGSSIMPQKRNPVVLE------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C1H6L6(24-234:299) Argininosuccinate lyase n=1 Tax=Paracoccidioides brasiliensis Pb01 RepID=C1H6L6_PARBA  E=2e-33 s/c=0.69 id=21% cov=41%
--------------------------------------------------------AFARANVATGILTKDEFASIENGLKQVLEEWRTNAFKIVPGVDEDIHTANERR----------------LGEIIGKEIAGKLHTGRSRNDQVATDLRLWLRDELRVVETYLVDLLKVIAERAESDIEYVMPGYTHLQRGQ------------------------AFDGL--------------------------------------IHNSMSAVGDRDFILETMQWGSTLMLHISRWSEDLIIYSTT---EFGFVRLsDAYTTGSSLMPQKKNSV---------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_O49514(81-462:467) Adenylosuccinate lyase - like protein n=2 Tax=cellular organisms RepID=O49514_ARATH  E=2e-31 s/c=0.36 id=22% cov=51%
------------------------------------------------------------------------------------------------------------------------------------------------------------------ILPTMDELIKSISLIAKNFAYVPMLSRTHGQPATPTTLGKEMANFAVRLSEERRYLSETKIK----GKFAGAVGNYNAHISAYSNIDWPHVSEEfvtsLGLTFNPYVTQ---------------------------------------------TTKAGEIGSSTMPHKVNPIDFENSEGNLGKANAELTFLSMKLPISRMQRDLTDSTVLRNMGGALGHSLLAYKS-AIQGIGKLQV----MRRY---------------GVPEPYEKLKE-LTRGKAVNEETIRTFIkgleLPSEAKDQLleLTPHTYVGAAAALALAVDEA--
>UniRef50_C9S992(32-271:280) Argininosuccinate lyase n=1 Tax=Verticillium albo-atrum VaMs.102 RepID=C9S992_VERA1  E=5e-26 s/c=0.50 id=21% cov=32%
--------------------------------------------------------AFARANAKSGIISKDEFTEIERGLREVQKEWE-ADAFVI------------MPNDEDIHTANERRLGEIIGK----DIAGKLHTGRSRNEQVACDMRLWLRNQIEEIEGHLIALIE---------------------RAMPVLWSQHLLSFGFYFANDLERLRETSKRVNRSPLGCGALaGNGFNIDRD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q87DC2(8-462:473) Fumarate hydratase class II n=130 Tax=Bacteria RepID=FUMC_XYLFT   E=1e-121 s/c=0.96 id=40% cov=95%
-SDRYRIEHDSMGDLRVPIDALWGAQTQRAIENFPISGR--SMPQGFIHALGFIKAAAAKVNAELGLLPKSMAKEIEAAALDVAA-GRYDAEFPVDIYQTGSGTSSNMNANEVIATLAM------RATKGPIHPNDHVNLGQSSNDVVPTAIRISATLAVQgRLLPALKHLRKMINKRARGLGSVVKTGRTHLMDAMPLTFAQEFGAWSAQIVSAEARLNDTLKRLHRLPLGGTAIGTGINTDPHFGRNAVKVLSALTGIHFESANNKFEGLAAQDDLVELSGQFNTLAVALMKIANDLRWMNAGPLAGLGEIELPALQPGSSIMPGKVNPVIPEAVVMVASQVIGHHTAVTVAGQSGNFQLNVTLPLIAYNLLESATLLGNVVMLLADKVIVGLKVRQDRVQEVLERNPILVTALNPIIGYEKAAVIAKRAYKEHRPVLEVACEESNLNPVELARLLDPAALTE--------------
>UniRef50_C5C2S8(20-478:540) Fumarate lyase n=10 Tax=Bacteria RepID=C5C2S8_BEUC1   E=1e-118 s/c=0.93 id=54% cov=96%
-----RTEHDLLGDRQVPLEAYYGVHSVRAVENFPISGVRLRRLTELINAIAAVKQASALTNAELGLLPQEKADAIVEACQEI-RAGALHDHFVVDVIQGGAGTSTNMNANEVVANRGLEVLGYARGRYEFLHPVDDVNRSQSTNDVYPTAAKVATYVAIGGLLDALETLQRSFAAKAVEFADVVAMGRTQLQDAVPMTLGQEFGAYAETIDEDRRRLAEARALITEINLGGTAVGTGLNAPREYPELARAHLAEITGIPLVTSPDLVEATQDAGAFVQLSGVLKRIAVKLSKTCNDLRLLSSGPRAGFGDITLPAVQAGSSIMPGKVNPVIPEVVNQVAFEVIGNDVTITMAAEAGQLQLNAFEPVIVHRLFMSIDRLRNASLVLASKCVDGIVANREHLRREVLHSIGLATALNPYIGYAAATALAQEALATGAGVAELALEHGLVEPDVLAQILAPENLVG--------------
>UniRef50_D2R695(1-472:474) Fumarate lyase n=4 Tax=Planctomycetaceae RepID=D2R695_9PLAN   E=1e-116 s/c=0.89 id=41% cov=97%
MSE-YRVERDSMGEVQVPAQAYYSAQTQRAVENFPISGWPL--PAALVHAMGLVKLACATANRDLGkltrtgknKLDDQQVAALLEACREV-ADGKLDKEFPVDVFQTGSGTSSNMNTNEVIANRAIEILGGNRFEKEkPIHPNDHVNMGQSTNDIFPTAIHVAVAMQIKsDLIPALERFQNVLATKAAEWDKIIKIGRTHLADATPLRLGQEIGGLARQMEMSIQRAKRAIDSVLELPAGGTAVGTGINTHPEFGRRVAEALSRETSIPFVEAVNHFEGNAQRDGLVECSGQLRTIASTLFNVSNNIRWLGSGPRCGFYEIQLPDRQPGSSIMPGKVNPVMCESMMQVAARVIGNDATVAFsGATGGQFQLNIMMPVMGLATLESVKLLAASCRAFVDFCALEMEANPEACEAAVEKSLAMVTSLNPHIGYENAAAMAKKAFKTGKTIRELCREDGVLPESTLREALDPWSMTEP-------------
>UniRef50_Q7V024(1-461:461) Fumarate hydratase class II n=11 Tax=Bacteria RepID=FUMC_PROMP   E=1e-115 s/c=0.91 id=36% cov=96%
MTKNFRFEKDSMGQIKVPSEALWGAQTQRSIINFSIGEELI--PIELIYSLTVIKRAAAISNFKLGLINNVKKDLIIEACTEIL-DGKHDSQFPLKIWQTGSGTQTNMNINEVISNIAALKTNSGLGSHHPIHPNDDVNKSQSTNDTFPAAIQISVVtQIIKKLVPSIKELTKVLDSKSNKWKDLIKIGRTHFQDAVPISLGQEVSAWSKQLKDAEDALIISLNELCFLPLGGTAVGTGINCPKDFSKESIKSISEYTGLFFYKSKNHFSLMASHDRLAQVMGQIKILASALFKISNDIKILSSGPRSGIYELIIPKNEPGSSIMPGKVNPTQCEALSMVCTQVMGFEYAVSIANASGTLQMNEYKPLIGFNILTSIKLLNHAISNFRLKLVEGIQPNPKTIKANLENSLMLVTALVPKIGYEKAAEIANLAFNESINLKEATIKLGYLTANEFEDAINTNKMI---------------
>UniRef50_A9A1H7(3-452:453) Fumarate lyase n=4 Tax=Archaea RepID=A9A1H7_NITMS   E=1e-110 s/c=0.89 id=41% cov=94%
----FRLDQDSLGKVKIPSDAYYGAFTGRAIKQYHVTGNT--SHENLIKSFVMIKRSAAVANMKTKAIDTKRGKAIVSACDKILA-GKHVDQFVVDMINSGAGTAFNMNSNEVISNVALEILRKKKGQYEFLHPNDHVNMSQSSNDTYPTAMHVAILMNLKETIPAIDILIKSLSKKAKQFSSFKKIGRTHLMDALPVTLGSEFAAYVTSITKARNELVASQKELQNVALGGTAVGSGANTPKGYRKIAIAELGKISKLPLRPEKDMQHGLQSKYAVANCSGALRNLALEIGKLANDIRLMASGPIAGLAEIGIPAVHAGSSIMPGKVNPSLAECMNMICFNIIGNDTAVSYAAQGGQFELNVMLPGMLKCMLESTDMIKNFLPIFSANLIDGLTANKDKLRADIENSPVIVTLLTPKIGYLKSAELFKESLKTGKTIRELVVSKKLMTNKEIDSLF---------------------
>UniRef50_A6DXB5(3-455:462) Fumarate hydratase n=2 Tax=Roseovarius RepID=A6DXB5_9RHOB   E=1e-105 s/c=0.85 id=39% cov=95%
----YRTESDSLGDVQLPDDTLYGSNTARALENFAGMGLPLSAYPDFMRAMALVKRAAAMANQEVGALASDVADAIIAACDEIVAGG-HADQFPTALLEGSGGTSTNMNFNEVIANRAGQILGDKPGCYVRVNPNDHVNCSQSTNDALPTAVKLACVLTGPSITAAIEILISALRVKADETNDMLRTGRTCMQAAQPMTWGQYFLGHASALSRALTAVQSAVETLRTVPMGGTAIGTGLGAFPGYRRAIAPALSEVFGMEIRLAEDPFDAMHAADGFVRLSAELRNLSAIMAKLAADLVILGSDGASGLGELRLPPVQPGSSIMAGKVNPVIPMTVQQVWMRVHGHDAAIAIAAQSGQMEINHFEPLIALSLFEQMALITAAAQRFAARCIVGLEVDEDRSYLNLAQSFGVSTVFLKELGYTRVSAMAKRALAEGKPLADIAVEDGLLSKTDIRDVLR--------------------
>UniRef50_C6VJS2(1-453:466) Aspartate ammonia-lyase n=14 Tax=Lactobacillus RepID=C6VJS2_LACPJ   E=1e-105 s/c=0.85 id=46% cov=95%
----MRIEADCIGKLAVPDDALYGIHTLRAVHNFPITTELMH--PLIMQSLVQIKKAAASVNAAAGTLSNDKAHAIIAACNQLLL-GRYADNFIVPAIQGGAGTSANMNVNEVVANLAHRLM-----PAVAVHPNDDVNQSQSTNDTFPTAGKMALCMQLPGLLTALSRLVQTLLVKSQRYQDAIKVGRTQLEDAVPTTYGRTFHAYYQLFKRDLTRVRQAGEHLRIVNLGGTAIGTGINATHTYQQQILVKLNQNTDLDLVAAPDLIDATQNCDLFVEFSAAMKTLAVDLSKFSNDLRLLASGPQAGFGELNLPAQQAGSSIMPGKINPVIPEVVNQVAFEVIGHDTTVTMAAEAGQLELNAFEPIMLRALLTSEQHLQQALTTLVDHCVRQLTVNRQRCADQVAHSAITATVLAPYLGYETTTALIKEALTTNQAIPELLHRRRLLSDALVEQLFSPAGLTQP-------------
>UniRef50_B4H329(32-141:537) GL13348 n=4 Tax=cellular organisms RepID=B4H329_DROPE   E=2e-28 s/c=1.17 id=41% cov=23%
-SQEFRVESDTFGELKVPADRYYGAQTMRSQINFPIGGTTERMPKPVVQAMGILKKAAAEVNKEFGL-DTKVSEAISKAADDVISGKLYDDHFPLVIWQTGSGTQSNMNVNE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q51404(2-454:458) Fumarate hydratase class II 1 n=12 Tax=Proteobacteria RepID=FUMC1_PSEAE  E=1e-100 s/c=0.81 id=37% cov=95%
---DTRIERDSMGELAVPATALYGAQTQRAVNNFPVSGQR--MPQAFVRALLLAKAAAARANVSLQQLDAPMGEAIADTCLQLLQE-DFMQHFPVDVFQTGSGTSSNMNANEVVATLASRRLGGK------VNPNDHVNCGQSSNDIIPSTIHIsAALEISERLLPALRHLEQTIQSKAGEVHAYVKTGRTHLMDAMPVRMSQVLGGWAQQVRQAGVHIESVLPALQQLAQGGTAVGTGINAHPRFAERFSQELNDLTGLAFRPGDDFFALIGSQDTAVAASGQLKTLAVTLMKLANDLRWMNSGPLAGLGEIELEALQPGSSIMPGKVNPVIPEATAMVAAQVIGNDAAIAVAGQSGNFELNVMLPLVADNLLHSIQLLANVSRLLADKAIASFKVNQGKLSEALARNPILVTALNPIIGYQKAAEIAKQAYREGRPIIDVALENTDLDRARLEVLLDPEKLT---------------
>UniRef50_B7HRS6(3-427:463) Argininosuccinate lyase n=66 Tax=Bacteria RepID=ARLY_BACC7   E=2e-90 s/c=0.79 id=25% cov=65%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNDQVATDMHLYLNEKVEHIIKATKQLQTVLVHQAENNIETIMPGYTHLQRAQPISFAHHILAYFWMLERDVNRYEDSLKRINISPLGAGALaGTTFPIDREYS-------AELLGFNG-IYENSLDAVSDRDFILEFLSNSSMLMMHLSRFCEELILWSSQ---EFQFIEMsDQYATGSSIMPQKKNPDMAELIRGKTGRVYGNLFSLLTVMKGLPLAYNKDLQEDKEGMFDTVKTV-EGCLHIMAGMLETMTVNKEKMGQAVTQDFSNATEIADYLankglpfrqAHEIVGKLVLHCTQKGIYLVDVPLETykemSSLFEEDLYEVLSP-------------------
>UniRef50_C0CW88(17-441:453) Putative uncharacterized protein n=1 Tax=Clostridium asparagiforme DSM 15981 RepID=C0CW88_9CLOT  E=1e-85 s/c=0.75 id=18% cov=85%
--------------------------------------RTIFDDRTIIQNFLDIEKALAQVQGEMGIIPKEAADEICKK--------GFVENLDIGEIEAGIVKVGHSLVP----------ILRNFQKKCDSGYGEYIHLGATTQDILDTGFMMSVKRGFEAVYRDALEAEEAVLDLVDRYADTVMAGRTHGQQAIPITFGYKAAVWASELRRDIERMEDCRKRCFVGQL-SGAVG-SMAGFGENGREISRRVIEALGLDVPDISWHV----SRDRLAEIVSVLATLGCTFGKIGQEIVYLQGTETGEAAE-GFVHGAVGSSTMPHKRNPVAPEALQTLS-RLAKAGMGATFDSMYQFHERDGASWKIEWMSVNETVMLVGGVAAKGKKLLKNLDVFPERMKANLDLLKGLMMsepvmlELGKKIGKQTAHEVVYEvsmaAFEEQADFKAKLLENevvaANMTEAELDALLDPERYTGDCAAIAR-------
>UniRef50_B9MRP4(8-437:462) Argininosuccinate lyase n=4 Tax=Bacteria RepID=ARLY_ANATD   E=3e-83 s/c=0.72 id=20% cov=76%
--------------------------------------------------------------AKCNIIREDEAKLIIDSLYQILEDFKLGK-----IVFGISDEDVHMLIEKELIKR-------------IGEVGKKVHTARSRNDQVALDERLFCREKNLYLQELIKTLINTITTLAEENIDVIMPGFTHLQKAQPILFSHYILAYAQMLKRDLLRLRHNYSMTNSSPLGSAALaGTTFEIDRFF-------VASELGFESVT-ENSVDTVSDRDFILEMLFSLAMIQMHLSRLAEDFIIFNTD---EFKFIELDDsFCSGSSIMPQKKNPDALELIRGKTGRVYADLIGLLTVLKGLPLSYNKDLQEDKEFLFDSIETVEMSLIVI-NEILKTLKIDKENMVNSCKSGFINATDLADYLvtkgvpfrdAHFIVGNIVKYCIESDKTLEDLSLEEYKRFCEKIQE-----------------------
>UniRef50_Q59092(16-433:451) 3-carboxy-cis,cis-muconate cycloisomerase n=14 Tax=Acinetobacter RepID=PCAB_ACIAD  E=4e-83 s/c=0.74 id=20% cov=81%
--------------------------------------------------------ALAQAQAQVGVIPQSAATVIERAAKTAI------DKIDFDALATATGLAGNIAIPFVKQLTAIVKDADE-------DAARYVHWGATSQDILDTACILQCRDALAIVQNQVQQCYETALSQAQTYRHQVMMGRTWLQQALPITLGHKLARWASAFKRDLDRINAIKARVLVAQLGG-AVGSLASLQ-DQGSIVVEAYAKQLKLGQTACTWHGE----RDRIVEIASVLGIITGNVGKMARDWSLMMQTEIAEVFEPTA-KGRGGSSTMPHKRNPVAAASVLAAANRVP-ALMSSIYQSMVQEHERSLGAWHAEWLSLPEIFQLTAGALERTLDVLKGMEVNAENMHQNIECTHGLimaeavMMALAPHMGRLNAHHVVeaacKTAVAEQKHLKDIISQvdevKQYFNPSQLDEIFKPESYLG--------------
>UniRef50_A0LEB1(9-436:466) Argininosuccinate lyase n=13 Tax=Bacteria RepID=ARLY_SYNFM   E=8e-83 s/c=0.72 id=25% cov=62%
------------------------------------------------------------------------------------------------------------------------------------------HTARSRNDQVALDVRLYMRDTLLQCRGLILQTQKVLVSCAEENLGVVMPGFTHLQHAQPILLSHHLMAYYEMLKRDDERFEQCFHRTNVLPLGSAALaGTTFPIDMEWT-------AKYLNFPRVT-SNSIDAVSDRDYLIEFGAASAMLMMHVSRLAEELILWSSTEFD-FIEIS-DAFCTGSSIMPQKKNPDVPELMRGKTGRVYGNLMALLTLTKALPLAYNRDLQEDKEPVFDTADTII-STLRLLSRLIPEIRFHRERMGEMAIQGFTLATDLADYLvkkgvpfrkAHHIVGQIVQYCLKNRKQLHDCTVEE---------------------------------
>UniRef50_A9A3T9(4-446:453) Adenylosuccinate lyase n=3 Tax=Archaea RepID=A9A3T9_NITMS   E=4e-82 s/c=0.70 id=18% cov=87%
----------------LPIDSgRYGTKEM----------MEIFSEQNKVDYQLQIEGAAAISQSEIGMIPKTVGRKIFKTANSGKITAKRIKQLEAKSDHDTA------------------ALVESLSEKCTKDARPWIHYGLTSNDLVDTSNSMQMRDALLIIEPKVAKIASILAKKAVKHSKVPAVGRTHGQHASIISFGLKFANWAAEMAKHVERIEEIKKRILICKTLGV-VGTG-SLMGAKSLEVQRRAAKRLKLFPAEVTTQVVP---RERYAEYVFELALIGATLEKIAIEIRNLQRTEIGEVAE-QFKKGQMGSSAVPVKRNPIKSERVSSLS-KLVRSQVALSFENIPLWHERDLSNSANERFVIPTVSILVDEMLETMTRIVSNLLVNEKRIVDNLYITKGQIFAefvlealikkgVPRFVAYRDVQRVAFLANDKGMLYKDAIKNDKaftsKLTDKEIDAIFSPEKHLG--------------
>UniRef50_C6CGJ3(15-435:454) Adenylosuccinate lyase n=11 Tax=Enterobacteriaceae RepID=C6CGJ3_DICZE  E=8e-82 s/c=0.73 id=18% cov=81%
-----------------------------------------------------VEIALALAEGELGVIPQDAADTIASHANASALNIEEIAQDAVRMKHSLMPTIAAI-------------------QKQCGEAGEYIHYGVTTQDVVDTATVLQLSQAFDIVVRDTRLVAIELKRLAKKHQHTLMTGRTHGMQALPTTFGFKLAVWLDEFVRHLQRLNEIRDRVLVGNI-NGAIGTY-ASFGELGPEIERHTLARLGLNTPNIGWQ----SARDRFSEYASVAVLVSGTLGKIGNELYNLMRTEINEIEE-PFSEGKIGSTTMPHKRNPAALEGLASLTAPLFKS-AALIHESMKVEHERDAMSWRAEWIALPEINIYLSAQLQNALGILRGMSVNEKQMRANLDLQNGLllsekvMFEIGKLLGKQTAHHLVYEcsmaAFEQNREFKALLLEHPVLSqhltADTLDAWLDPANYVGSA------------
>UniRef50_C0GQD4(7-440:469) Argininosuccinate lyase n=1 Tax=Desulfonatronospira thiodismutans ASO3-1 RepID=C0GQD4_9DELT  E=2e-80 s/c=0.70 id=23% cov=75%
-------------------------------------------------------RAHARMLAHAGIISEDELQQILSGLDRI-ENELEQDEFTWDP--------GLEDVHMNIEKRLTDLIGA---------PGQKLHTGRSRNDQVALDFRLYTAAALQEWQQVLKELIQALTRQAQAHRDTLIPGYTHLQPAQPVCLAQHLLAYARMFMRDHERIEDALPRVKVSPLGAAALaGTTYPLQP-------EQVAEHVGFEYVFK-NSMDAVSDRDFVLEGLFIASMIMMHLSRLGEEIILWSNP---GFGFIILPdAYSTGSSIMPQKKNPDVAELVRGKTGGVYGRLMALLTTMKALPLTYNRDMQEDKEPFIEAHRSVSSSLRVMA-GMIAQTEFDRERMFGALKDGYLNATELADYLvargmpfrqAHHITGRLVAFAEEKGLGLEDIDLD----------------------------------
>UniRef50_C0CW77(1-428:439) Putative uncharacterized protein n=1 Tax=Clostridium asparagiforme DSM 15981 RepID=C0CW77_9CLOT  E=2e-78 s/c=0.69 id=20% cov=87%
-------EEEYYGSRDVQEDVFGGANT--------------------IQKMMDVEAALAWAECEVGLVPEQYAGEIQKKCSVELLDEA--------VYAEARRTTGHPLMGMLRAYKAI----------CSKEAGEYIHYGATTQDISDTALILQLREAWDIVEDKTRRLRKILAGKAREYRSLVMIGRTNDQQAMPITLGFKISTWIDELDRCLERMAQGRERI-FVGQFAGAVGT-MASLEQNGPRVQKLLFERLNL----AAPKISWFATRDRLAEFTFDLAMICGAVGRMGNEVYNEQRSEVNELAEGYA-QGKVGSSTMPHKRNPFLPGRLAGR-GRIAGTLVMRAMQCLENTNERDCRTLCIEPYHLKEICCLADGTLDIALELFGQMEVHEDQIGHNLEIlqgliySEALMMRLAEVYGRMEAHELVYElamaAIGQKRQLKELALADSRvtahLTEEELENLMRPEHYTGLA------------
>UniRef50_C8VJ67(1-455:463) Arginosuccinate lyase (Eurofung) n=6 Tax=Leotiomyceta RepID=C8VJ67_EMENI  E=6e-78 s/c=0.65 id=17% cov=79%
--------------------------------------------------------AFARANTKSGILSAHEFSEIERGFKQIAEEWS-TNTFVVKPNDEDIHTANERRLSEII----------------GKEIGGKLHTGRSRNEQIATDLRLWLRDELRKLDAFLSDLIKVSIARAESEIDYIMPGYTHLQKAQPVRWSHWLLSHATAFADELKRLREVTKRVNRSPLGTGALaGNPFHIDR-------EAMAKELGFEG-LLYNSMNAVGDRDFAMETMQWGSSFMLKISRWAEDLIIYSS---LEFGFVRLsDAYSTGSSLMPQKKNADSLELLRGKAGRAFGHMAGLMCTIKGLPTTYNKDLQESVEPLLDHIKTVGDSIQI-ATGVLSTLTTIPEKMAAAL-APEMLATEFADYLvrkgvpfreGHHISGRVVQLAEKHGVPMDQLSLEQlKSVDDrfgDDIQECLDYERAVE--------------
>UniRef50_D2QNX9(26-427:438) 3-carboxy-cis,cis-muconate cycloisomerase n=1 Tax=Spirosoma linguale DSM 74 RepID=D2QNX9_9SPHI  E=1e-77 s/c=0.73 id=20% cov=82%
--------------------------------------------------MLRFEAALATAQANNGLIPTPSAERIAACCTVELLDWERLKKDI--ALSGNAAIPLVKQLTEVVRKRDEEAAG-------------FVHLGATSQDVVDTATVLTIKSVLDWLDDKLSALANRLIALTQAHRQTVMIGRTLLQQAKPITFGLKTALWLDGLGRSQQRLAACRQRVLVLQL-AGAVGSRNASIPD---AVHQETANLLGL-----ESSVSWHTQRDNIAELAAVMGILSGSLAKIANDVMLLMQTEIAEVLEGKA-AGKGSSSTMPHKRNPVTTTAILANANRVP-NLVATMLSAMPQEHERSAGRWHSEWDVLTDIMQLTAGSVERSLELLDNLEVDSQRMRQNLELTNGLIyaetisLALAPKLGKATAHELVEKacavAIAEQKHLKDVLREQA-IDVADLDKLFKPENSLGQA------------
>UniRef50_A6V1T0(53-471:483) Probable lyase n=6 Tax=Pseudomonas aeruginosa RepID=A6V1T0_PSEA7   E=1e-73 s/c=0.67 id=17% cov=81%
-----------------------------------------------------VEAALALAQADVGIIPREAALEIARAAR--------LSAVDLRQIAEGVATTGHSLMP----------LLGALQKNCGASAREYVHFGATTQDIQDTAQSLEMRDVLDETERALDRLLERLATLASGKRDALMVARTHSIPALPTTFGLKVAGWIDELLRHRERLGEARKRILVVQLFGG-VGT-MAAFGAEAMALLERFASRLALDVPLAGWHV----SRDRVTEFVSTLAMVTASLARIADEIRTLNRWEIGEL-EVGWTQQQIGSSTMPHKRNPEGCEQVVVLA-RLAKAQVMLALDAMILEHERDYRGTRLEWCAVADVSHYALMAMSLLDDTIGGLTVHDEAMARTADAysdaicTEAFVFEMAKQLGKSSAYEIIfeitQACQRKRIPMRQALESDPRVSavmpKETLARLFEPRTHLG--------------
>UniRef50_Q1DAL5(4-417:437) Adenylosuccinate lyase n=4 Tax=Bacteria RepID=Q1DAL5_MYXXD   E=8e-73 s/c=0.67 id=18% cov=65%
------------------------------------------------------------------------------------------------------------------------------------------HLGMTSSDVLDTSLALTLRDALDLILKDVDRVMAAVEKRAFEHKHTLQMGRSHGIHAEPITFGHKLAIWYDELRRARTRLEHARD-VIAVGKISGAVGTFAHLPP----AVEEHVCRKLGLKPAPASSQVVQ---RDRHAEFFTALALLGSSIEKFAVEIRHLQRTEVRE-AEEPFTAGQKGSSAMPHKRNPILSENLTGLA-RLLRGYAVSAMEDVALWHERDISHSSVERVIGPDATILADFMLIRFARLMEDLRVYPEQMKKNLDllggvvNSQRLLLELARkGMDRQAAYVIVQRNamklYEEGLDFRQALLADedlrKMMTPEEISDCFS--------------------
>UniRef50_C6HWT1(5-443:486) Argininosuccinate lyase n=1 Tax=Leptospirillum ferrodiazotrophum RepID=C6HWT1_9BACT  E=1e-71 s/c=0.62 id=22% cov=78%
-------------SKEIPSSKPWGGRfaesTDKDVERFTES---ISFDGRLFREDIRGSRAHARMLARVGLLTPEELGQILQGLDRVEEEFS-------------AGRVELRSDWEDIHMHVEKRLVHHAGA-----AGLKIHTARSRNDQVALDLRLFVRRAAEDLIDALDRLLRATLMKGYGYRDLILPAYTHTQQAQPVSGGYYFGAYAERLLRDRKRLRGVIDSAGLSPLGSGALaGTTLPIDREF-------VASELGFSGVT-QNGLDTVGDRDFVADFLHALSLLMVHLSGWSEEWILWST---REFGMVRLPDRlLTGSSMMPQKKNPDILELIRGKAGRVVGDYTGLLVLLKGLPLSYNRDLQEDKEALFDAVDTVAGSLL-MMRLAVEGMAFETARIEEILSKTELLATDIA--------------------------------------------------------------
>UniRef50_C0VS79(21-438:444) 3-carboxy-cis,cis-muconate cycloisomerase n=4 Tax=Actinomycetales RepID=C0VS79_9CORY  E=9e-71 s/c=0.65 id=17% cov=74%
--------------------------------------------PAVVQNIVTVEVTLAKVQGELGMLPADASQKIS--------------QFSTIRPELVEKVEAGKIGNPLIAAL------DALRSEIPDAYRGWVHYGATSQDILDTARALQIKQSLDWLEEQLTELENLISSLTKEHSSTLMVARTNGQHALPTTLGMRFARWLAELRRCQSRLSDVRSRALLIQF-SGAAGTY-ASMGNQGLEIAERMAKELGLVFEAVPWH----ASRDSITELCCALAIYGQSLAKIAEDLFDMQRTDLMEARE-SMDAHASGSSTMPQKLNPFSTMKI-SVGARLAAGMAATVLTQPPGSFERDHRQLEVERDALPQIFVAVEGAAQKLNKLLPRLSFSKENLSQATHKegvlllTESLMMHLAPILGQEKAHQL---------------------------------------------------
>UniRef50_Q1MPM6(12-413:443) Adenylosuccinate lyase n=7 Tax=Bacteria RepID=Q1MPM6_LAWIP   E=9e-71 s/c=0.67 id=19% cov=45%
-----------------------------------------------------------------------------------------------------------------------------------------IHLGCTSSDIVDTATSLLLIEAGELILKGFDKLLTSIESLALKHQGLLCMGRTHGVHAEPTTFALKFANFFAEIQRDKERFVQAFNGIHVGKF-SGAVGTYT----FLTPEVETIACDILGLKPDTISTQVIQ---RDRHAEYFTALAITAGSIERLCVELRHLQRTEVREVEE-GFQKGQKGSSAMPHKKNPISAENMTGLSRLIRGNVLA-ALENQALWHERD--------------------------------------------------------------------------------------------------------------------
>UniRef50_D0U617(45-427:469) Argininosuccinate lyase n=2 Tax=uncultured actinobacterium RepID=D0U617_9ACTN  E=3e-69 s/c=0.69 id=21% cov=57%
-----------------------------------------------------------------------------------------------------------------------------------------VHTGRSRNDQCVTALRLWTKRELAALAERLIALCDVLTQRADLAGwgsdGVYLPGYTHVQRAQPVLLAHHLMAHAWAFTRDIDRLISTIKRADVSPLGAGALaGSSLPLDPNFT-------AREMGFADRF-SNSLDAVSDRDFVAEALFDLALIGTHLSRIGEEWVLWTSE---EFGFATLDDrYATGSSMLPQKKNADIAELARGKAGRLIGNLTGLLTTLKGLPLAYNRDLQEDKEPLFDSYDQVSLAVGALT-GMIQTATFNSDRMREAADVQSLSATDLAEYL-----------------------------------------------------------
>UniRef50_Q5U9J2(14-443:451) Fumarate lyase n=2 Tax=Nocardioides sp. JS614 RepID=Q5U9J2_NOCSJ   E=3e-68 s/c=0.61 id=19% cov=82%
-----------------------------------------------IQSWLEILAALAEAQAEFGIVPEDAARSIRENAD-----VRRLDLVRVGELTRSTGHSTLG-------------LIRCFQEILPSSAREWVYYGATVQDVSDTWTSIVLQHVALVLDRDLARAERAARRLAETYADTVMCGRTHGQPGLPITFGFKAAVWASEVARHRERVAQGAARWGVAQLGG-ALGT-MEFWGEQALPLLDSFASRLGLKAPD----IAWLTSRDRIAEFVGLLGMVTATLGKIGQEVYQLQRPELGEVRE-GLHRGVVGSITMPHKVNPEISEHLVTLA-RIVRSKVGPALEAMLHEHERDGRAWKAEWIFLPEACILTGATLSMSCQLLEELEIDEDRMMANLEDrggylmSEPVMRELSPLLGKHVAHELVHsiaiRGREQGVGFEEVLLAertlDGLLSADEIRKALDPVAAVGSA------------
>UniRef50_A6F014(27-408:447) Fumarate lyase n=1 Tax=Marinobacter algicola DG893 RepID=A6F014_9ALTE  E=4e-68 s/c=0.68 id=22% cov=55%
-----------------------------------------------IKAMLKVEGQLALAQADVGLIPQEAADAINQATQLLEP----------DLVALAAGVAS--------AGVPVPALVKALKKTLSQDFARWVHFGATSQDIVDTALILNCRELIKIYRQRLLEAIRLCVQLAEAHRGTLIAGRTRTQQAIPMSFGLKVANWIAPLLRQFERLEELVPRLLKVQLGG-AVG-SLAAMGDGADAVVKNLADRLSLQNAP-----SWHAQRDSLVEFSGWLAMTTGILGKMAEDWLRMAQTEVGELRF----SNGGGSSTMPQKCNPVNAEIM----------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q024T3(2-428:460) Argininosuccinate lyase n=1 Tax=Candidatus Solibacter usitatus Ellin6076 RepID=ARLY_SOLUE  E=1e-67 s/c=0.61 id=16% cov=66%
---------------------------------------------------------------------------------------------------------------------------------------DKIHTGRSRNEQVSLDTRMWLREESTDLQAQLFAVMGRLLDLAEMYPHAIIPGYTHMRRAQAVLWPHYLLAYFEMFLRDWHRFGDARRRANVLPLGSGALaGSGFPLDR-------EAMAQNLGFEGIT-QNSMDVSGDRDFALDFLYACTVTMIHLSRLAEDWILYSSEEFGWLE--LGDGVTSGSSLMPQKKNPDSLELIRGKSGRVVGCLTSLLVTMKGLPMTYNRDMQEDKIPIFDAADQLSGSLL-MTSAVIESTRLNPARPAAAAEESWVVATDLAEALARagtpfHQAHQIVGRfvlesVRANKKPSDWTAEEMHAFAPEftpDFAALLNPAE-----------------
>UniRef50_A5CSI8(52-463:497) Argininosuccinate lyase n=147 Tax=Actinobacteridae RepID=ARLY_CLAM3   E=2e-66 s/c=0.62 id=19% cov=61%
--------------------------------------------------------------------------------------------------------------------------------------------GRSRNDQIATLVRMYLRDHAAVIHAMLVQLVDALAAQAEAAGGAIMPGRTHLQHAQPVLLAHHLLAHCWPLVRDLERLADWDARADVSPYGSGALaGSTLGLDAG-------AVARDLGFA-RSSENSIDGTAARDVVAEFAFVLAQVGIDLSRLSEEIILWNT---REFGFVTLsDSFSTGSSIMPQKKNPDIAELARGKSGRLIGNLSGLLATLKGLPLAYNRDLQEDKEPVFDSVQTL-EVLLPAFTGMIATLRFDTDRMAELAPQGFSLATDVAEWLvkhrvafrdAHEVTGELVKAAESRGVGLEDLT------------------------------------
>UniRef50_Q0SH25(24-440:450) 3-carboxy-cis,cis-muconate cycloisomerase n=7 Tax=Actinomycetales RepID=Q0SH25_RHOSR  E=2e-66 s/c=0.61 id=19% cov=83%
-------------------------------------------------ALVEVEGALARAEAKCDVIPAASADAISSVFARVVAEGSVD--------VGALGVAAAAGGNPVIP--LVKLLRSEVAAADLGVSGSHVHKGATSQDILDTALMLLCRRSGAHILASLDEAVVCAEALARAQRDTPIAGRTLGQQALPTTFGVLAAGWMTALHRASRALFDALDGLPV--QLGGAAGTSAALYPH-GLDVADVLADELGLARQDVPWHTD----RTRIALLASALGTAAGAVSKIATDLVFLSSTEVGEVSE----GSPGGSSAMPHKRNPVAAIAARAAARRTPG-LVATILGSMDHEQQRAAGAWHAEWETLTDLLRLTGGAVARIADSLGGLNVHPDAMARNLDITGGLLLAerVTGALSARTdnARALVTAACETGHPLDEDPGLLEYLQADEIRALLDPAGYLGHAH-----------
>UniRef50_A3MSF0(8-383:408) Fumarate lyase n=5 Tax=Thermoproteaceae RepID=A3MSF0_PYRCJ   E=2e-63 s/c=0.65 id=21% cov=72%
-----------------PFDWRYGSEEVRAL----------FTPQAFIDAYVEVERALVCALEELGVAERGCCEAVGKAsvsAEEVYELEKKTGHDVLSLVLLLEEKSGCR----------------------------FVHFGATSNDVIDTAWALLVRRALGHIKRKVNAVGGELASLAARYRRLEMVGRTHGQWAEPITLGFKFANYYYEL-HIACRLLALAEDLMRAKLGG-AVGT-MAAWGELGPAVRERVAQRLGLPYHPIST---QVAPRETFAVLASALAVLSSVFERLAVEVRELSRPEIGEVVE-----RGGGSSAMPHKANPTTSERIVSLA-RYVRSLVSVALENVALWHERDLTNSANERVWIPQAILAVDEILDSAARLLKSIHVDEGRIRENLEKAL---------------------------------------------------------------------
>UniRef50_UPI0001AF729D(21-429:457) fumarate lyase n=1 Tax=Mycobacterium kansasii ATCC 12478 RepID=UPI0001AF729D  E=4e-63 s/c=0.60 id=18% cov=80%
--------------------------------------------------FLQVEAELAAAQADLDMIPAEVAPALRAVTPDHLDIARLAAR-------------------TQAAGYPIVGLVEQLAAIVPDGLGQYAHWGATTQDIMDTAAVLQIVAALDVIERDLLHTLAALTTLETQHGSELMVGRSQLQHALPITFGYRVACWTAPLLRHLDRLAELRPRVAVVQLGG-AVG-SLASMAPHGLDIRRELARRLGL----AAPSISWHATRDRFVEVVAWAAQVAASLGKIGLDIVVGSQTELAELSEPSAPGRGV-SSTMPQKRNPIGSQQLI-RAARLTRSYLDLALDGAVADCERATAVWSLEWHTVAPALAVCGGAVRTAADVLAGLHVDSAAMAANLDRTHGMIMAesvmmrLAPVLGRQAAHDqletLVTASLESGESFATLVARR----DPKLADAVTPAAYLG--------------
>UniRef50_B8D0M6(11-447:462) Adenylosuccinate lyase n=2 Tax=cellular organisms RepID=B8D0M6_HALOH  E=2e-61 s/c=0.55 id=20% cov=68%
-----------------------------------------------------------------------------------------------------------------------------------------VHLSATSFDIVDTANSLRYKEATEKLIvPALERLLEQWLNLAEQERDTLQIGRTHGQHAEPLTFGLVMAYYASRLHERIVNLEKVVSSL--CGKMAGAVGAYNAssLFFEDPEEFEKEVLKELGLKPAPVSTQIVP---PEYMTDYVHSLITVFGVLADFSDDMRHLQRTEIGETGE-YFAKDQVGSSTMPHKRNPINYENVKSMWKTFMPRMVTMYLD-QLSEHQRDLTNSASGRFIAEIASGLMMTVDRLY-KVSSRMKINSRKMKNNFNLSKNMIIAEPLYIflaaaGHPDAHEYVRkltlKADKEGKDLVELIKADKeietylaKLDKRQKDILYNPEQYTGIARE----------
>UniRef50_D2RUT8(67-507:554) Argininosuccinate lyase n=1 Tax=Haloterrigena turkmenica DSM 5511 RepID=D2RUT8_9EURY  E=8e-60 s/c=0.53 id=21% cov=59%
------------------------------------------------------------------------------------------------------------------------------------------HTARSRNDEVAACIRYRLREDVLESIETTLALRESLVAVAEAHAETIMPGYTHLQPAQPTTVAHWALAYEGAVRRDTARLLEAYGRINESPLGGAAfAGTTFDIDR-------ERTAELLGFDGGPAsnargssaeqrsavvvENSMDASSSRDFLLEATQALSTHATTLSGLAEDVVIFANRGFVDLS----DDYSSTSSIMPQKKNPDTLELVRAVAGDAAGGVQGLTTTLKGLPRAYNRDLQRATTHAWDTVDAVTEASEV-AAGAVATADWNEETLAAEAGEGFSTATGVADLLAanglpFRTAHELVAHAAE---------------------------------------------
>UniRef50_A5G255(16-435:461) Fumarate lyase n=1 Tax=Acidiphilium cryptum JF-5 RepID=A5G255_ACICJ   E=1e-58 s/c=0.55 id=17% cov=68%
-----------------------------------------------------------------------------------------------------------------------------------------VHWGATTQNVVQTGRVLLMRRAHAALMRRLAAILDRLAGFAEAEAGTVTVARTNIRHALPITFGFKAGGWIEEFLRHEERFREAAPRVFRAQWGG-AVG-AMHAVGEAGPELNRRLAARLGLGWHEIP----SRAGLDTFAEYVLLLGMFAATCGKIARDLYVMMSDEFGEVIE-DLGEEVIGSSTMPHKVNSKIAVHVIALSARV-RAQVPLALEAMQPSFEGDGANNQMLSALIDQACPLAYELAAQMDELLAAIRLRPAAIGRNLAMSGAFmasenaMMALAPLLGRTVAHDIVHhaiaEAVETGGDLATLIAaapdAAGRVDAAMVRDALDPSSYIGQSVALAR-------
>UniRef50_Q123L3(40-454:513) Argininosuccinate lyase n=2 Tax=Burkholderiales RepID=Q123L3_POLSJ   E=3e-57 s/c=0.54 id=19% cov=65%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRIDQGATVRRLYKRNRMLDVMDQLNGLQDAIAQQARRHARTIMPGYTHLQHAQPWVFGHYLLSFSSRLHDSFERLAQAYGRVNRNPLGAvGLAGTSWPLNRM-------RTTALLGFDG-LVENSKLGREA-YYAAEAIGALAFVMADLNDLATDLHLWSSTEFGLVE--SDDSYCGTSSIFPQKKNPAGLETIKKAAGSAVTWLATALATFRA---EGTGDQAMRELPLIDEALATTEGMLDLFTGVIETLIVHDDRMAESLSGSWCTASNLADVIvrerglsfrqVHHIVARVVRNCIAQGTApadltsalLDEAALETAglelRLGDEAVRDALDPRRFVE--------------
>UniRef50_B0R3B3(12-456:458) Adenylosuccinate lyase n=10 Tax=Halobacteriaceae RepID=B0R3B3_HALS3   E=4e-57 s/c=0.50 id=16% cov=86%
--------------------------------------------AALMRARVEVEAEYVLALADLDAVPLELVGDERTALRDAYKTFDAADADLVKRIETEGALGHAATNHDV------KAVEYFLREHAPARAHSWIHFGLTSEDVNNLAYRLLVDGAITAVLtPELRGLRDDLVSFAHDYADLPMLARTHGQPATPTTFGKEMAVYAARLGRALARITDAVDGLT--GKLAGASGTWAAHTAAFPDVDWRSFAARfvdsLGLAYAEPTTQVNPC---DDLTAVFDAVAGANGVLEDLAVDAWLYVSQRYLG---QDAADGETGSSTMPHKVNPIDFENAEGNLAKANSDLGFLGDSLTTSRLQRDLSDSTVKRNIGAAFAHCLLAYRKLGDG-LDAVTPNEAVLREDLRANPEVIgEAVQTILrreGHDDAYERVKALTRgERVSLDDfkELFASLDIDADTRDELlaLTPERYVGVAADIAR-------
>UniRef50_Q9UX32(6-420:444) Argininosuccinate lyase n=9 Tax=Sulfolobus RepID=ARLY_SULSO   E=1e-56 s/c=0.54 id=23% cov=66%
-------------------------------------------------------------------------------------------------------------------------------------------LGRSRNDHVATALRLRLRNKLIELLTDINSLRKILLDKAKEHITTIFPSYTHLQLAQPTTFAHYLTYIEEELASRWEIIFSTLKQVNKSPLGSGAiVGTNVKIDREKE-------AELLGFD-SIIYNTLSATSSRADILSTISELTVLMVVLSRIAEDLIFFSSNKL-----IKLPDSHVsTSSLMPQKRNPVTMEILRAKAAESIGMLTSLLSIYKGLPTGYNLDLQEMNKYYWLVINYTKSSIGVL-SSLFSQIQVNKINIDES-----SLATDDAELLSiskkvpyrstyFEIAKKVREGSYKSTLKIEDSINMKAVIGSPNFDLMANLIKI----RETKLKEDEKE-
>UniRef50_B2SEM1(12-421:432) Adenylosuccinate lyase n=19 Tax=Francisella RepID=B2SEM1_FRATM   E=2e-56 s/c=0.54 id=17% cov=68%
------------------------------------------------------------------------------------------------------------------------------------------HFGVTSSDIIDSALSLQIRDSMSYVIKDLEALCDSLLTKAEETKEIITMGRSHGMFAEPMSFGQKFLGAYVEFKRRLKDLKDFQKDGLTVQF-SGAVGNYCIL----TTEDEKKAADILGLPVEEVSTQVIP---RDRIAKLISIHGLIASAIERLAVEIRHLHRSDVLEVYE-GFSKGQKGSSTMPHKKNPISTENLTGMA-RMLRSHVSIALENCVLWHERDISHSSAERFYLPDNFGIMVYALRRMKNTIDNLVVQRDIIEDRVRSTSAylssfylhFLVANTPFM-REDCYKIVQQVafdLKQGESF---SKKLQKVMHDEHNIILDILEMDFEGIK-KTYLKE---
>UniRef50_Q8U483(21-385:459) Argininosuccinate lyase n=1 Tax=Pyrococcus furiosus RepID=ARLY_PYRFU  E=5e-56 s/c=0.61 id=23% cov=59%
-------------------------------------------------------------------------------------------------------------------------------------------LGRSRNDHVVCALRLKAKKALVEEIGLILELRKALIKKAEENVYTLMPLFTHLQPAQPSTFAHYLSAIIEELEDITKILFSGLGIVDKSSLGAGAIgGTSVLLDRGYMGGI---------LFSDIITNSLYATSSRTFLLYSCFLSVLISIALSRIAEDFVIFSTP---NFGYIKLPnEHLSTSSMMPQKKNPVTMEVARAWAGEAIGHLVAMMSILKALPSGYNLDMQEVNKHAFALFSGTIKTLKIFVDAM-KRVEVNKENMKKDCDIFPILATDYAEKI-----------AMNTGRPYREVYME----------------------------------
>UniRef50_A0P1F3(22-435:437) 3-carboxy-cis,cis-muconate cycloisomerase n=2 Tax=Labrenzia RepID=A0P1F3_9RHOB  E=5e-54 s/c=0.52 id=19% cov=65%
--------------------------------------------------------------------------------------------------------------------------------------------GATSQDVIDTAMVLQAKVALEILGARLEKLIDTLERQSARHADQLMAGRTRSQVATPITLGYRIAQWAHPLIDAENALPALRSAVLRVQFGG-ASGINSAIAPD-GTTVSTALALELGLEDSPSWHV-----NRTPILALAGWLQQLTSALAKMAGDLALSGRTDIAELA----SGTGGGSSTMPQKANPVQAETIQVLNSIAIAAQAGLAAAASPLE-ERDGTAWPLEWHFLPQMLLAAGAALVHAEDLATSLQAHeanlaatlaanPEIMAETA--SFVLA---RNGVSRAEAKDLVAAAAKDPAPFAEALARLAPVS-LDWQKELDPHQVVAPA------------
>UniRef50_Q11KV9(45-438:502) Argininosuccinate lyase n=1 Tax=Chelativorans sp. BNC1 RepID=Q11KV9_MESSB  E=9e-54 s/c=0.54 id=20% cov=64%
--------------------------------------------------------------------------------------------------------------------------------------------GRSRNDLANAGKRMFLRDQLLRTIEAVIGYREAVVHKAADHLDTVMVVYTQRKEAQPITLGHYLMAISENLAKNLDRYRELYARINLCPLGAAAtAGTGWPLNRD-------RTSALLGFDG-LVVNSIEGVAGWDHVAEHAFVNAVFLSGLSRLASEIQLWSTDEY-QVAELDA-SFAGTSSIMPQKKNPDSLERSRKAAFAAMGPLVGILTSLNAIEYQYSAARVELEPRSIDALIAATHAM----TGVVRTLHPNKERMRQYAAENYSTMTDLTDMLVrrvgidYREAHEIVAHvvitAIEKGIKankigldlVQEAAVAQTgagiNVSADDIKDALDPWQ-----------------
>UniRef50_Q08Q17(1-404:458) Argininosuccinate lyase n=1 Tax=Stigmatella aurantiaca DW4/3-1 RepID=Q08Q17_STIAU  E=5e-53 s/c=0.52 id=22% cov=65%
--------------------------------------------------------------------------------------------------------------------------------------------ARSRNDINATVTRMRLRPALAEVLRQGMLLASQLERLGVAHAQTLMSAFTHLQPAQPATFGHYLGGVLSELLRTLDWIAGAYDTLNRCPMGAAAgVGTSFPIDTTI-------VAELLGFE-SPLGNSLDAVGSRDYVVQVLSGLALLGTLLTRMSADLQTWASSAYGFLGWP--DELVSTSSIMPQKRNAFVLENIRGQAVKATGFLMNTLMGLKSTSFTNSVEVSSEATSPVWPALEAARTALVLMELLMSNVIVQPEPMRRFLVGQDTTMTALADHlvarhgLAFRTAHDVVGRLVnlkrepeltpQAARGLLEPLLATTLgrevsLDEAELAQVLEPE------------------
>UniRef50_B8LE99(27-464:497) Adenylosuccinate lyase n=1 Tax=Thalassiosira pseudonana CCMP1335 RepID=B8LE99_THAPS  E=6e-52 s/c=0.47 id=19% cov=63%
---------------------------------------------------------------------------------------------------------------------------------------------------------IQLKEALKLVQRKLVQTIAILKDFAEKHKDLPTLGFTHYQPAQLTTVGKRCTLWIQDLLMDYERVTYELENLPMRGVKGTT-GTQatflelFNGDHDKVKQLNEKVCAMMGF--TKCVPVSGQTYTRKIDYHILSLLSGIAQSAYKMCGDIRLLANLKEV---EEPFAKNQIGSSAMAYKRNPMRSERVCSLSRYVMSLPPSAANTHANQWFERTLDDSAIRRIILPEGFLAVDVVLNLLMNIADGMVVWPNVVEKHVMEELPFMATEVILMecvkaggDRQELHEAIRVHSMaagavvkgEGKPndLMERIAADSLFAAvhDKLDELVDPK------------------
>UniRef50_UPI0001B4C156(96-458:498) argininosuccinate lyase n=1 Tax=Streptomyces hygroscopicus ATCC 53653 RepID=UPI0001B4C156  E=3e-51 s/c=0.56 id=21% cov=69%
----------------------------------------------------------------------------------------------------------------------------------------DIQRARSRIDQKATGVRMADRAALLHVMRELLRLGEVLLDAGAAYDAVIAPGYTHLQHAQPTTLGHYFNAHYWTVSRNLARMAQLYERLNECPLGGAAhSGTDWPIDR-------EATAAYLGFARPVRNARDAGLSALDAGAELAAVLGLTLSGVSRCASDLFYWSSSEVALVR--LHPSLCGTSSMMPQKRNPIVLERIRGLAGDAAGWTASQLGVLHFATST--DADQGYVHNRMPGYCHETAGAIHLLAQSVATLEVDAERLRRSAERHWSTASALADDLvrvhgmsfrdAHETVARFVTAHEAAGATEGTIrpDLADGPLrdyTPDQLRHLLDVQSFvdgrhsaggTSPARRAELATE----
>UniRef50_A8ACF4(43-403:452) Argininosuccinate lyase n=1 Tax=Ignicoccus hospitalis KIN4/I RepID=A8ACF4_IGNH4  E=1e-50 s/c=0.56 id=21% cov=54%
-----------------------------------------------------------------------------------------------------------------------------------------INLGKSRNDQVATAIRLRVREELLESATALYHLLKALYAKAKLHEEVFFPTFTHLQPAQPANFGLFLTNFAEEIVDSFGLLEVALEITDKCPLGaAAAAGSTVDLDR-------RRRCEELCFK-DLAYNTLYATTSRDFALVSLGALASLSIPLLRFVEDVFVYATPP---FSLIRVPlDHAGTSSIMPHKKNPATLEVVRAELSKLLGHYVSAFSILKGLTSGYNLDLQQLTPLLWQAFKTFRKSVIVITDF-LWKMEVNEERAKEFL-------------------------------------------------------------------------
>UniRef50_Q7CV75(22-345:353) 3-carboxy-cis,cis-muconate cycloisomerase n=12 Tax=Rhizobiales RepID=Q7CV75_AGRT5  E=4e-50 s/c=0.62 id=19% cov=54%
-----------------------------------------------IDAMIRFETALAQAQVGTGIISEDVAKAIVSGLSE----------FAADMTALRHGVAKD--------GVVVPELVRQMRAAVAGKAAEKVHFGATSQDVIDTSLMLRLKMATEIIAARLGRLIDALGDIAARDGHNALTGYTRMQAAIGITVADRAASWIAPLERHLLRLETFAQSGFALQFGGAA-GT-LEKLGDNAGAVRADLAMRLGLADKQ-----QWQSQRDGIAEFGNILSLVTGTLGKFGQDIALMA-----EIGTEIRLSGGGGSSAMPHKQNPVNAETL----------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A3KFG3(25-403:480) DabB n=2 Tax=Actinomycetales RepID=A3KFG3_9ACTO   E=3e-48 s/c=0.51 id=24% cov=38%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNDIKATTTALRLREQVTALAAELLRLQAILLNRARVHAGTVMPIYTHFQPAMPVTYGYYLTGLALAVGRDVLGLRQVLAGLDRSPLGAGAVaGTDLPIEP-------ARTAELLGFAGPPV-HATDAVASRDGVLRALAAAATAGVTLSRLGTDLQLWSTQ---EFGFLVFPDRlVGGSSAMPQKRN-----------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q5ZXD1(11-454:456) Adenylosuccinate lyase n=291 Tax=cellular organisms RepID=PUR8_LEGPH  E=9e-46 s/c=0.42 id=14% cov=61%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------PTIAEIMGSITLLGKQHADVAMLSRTHGQPATPTTMGKELVNFVARLKRPQQQLAEVLIPAKFN----GAVGNYNAHVAAYPEVDWRKHCAnfvtSLGLSFNAYTTQIEP---HDGIAEVSQIMVRINNILLDYTQDIWSYIS---LGYFKQKTIAEEVGSSTMPHKVNPIDFENAEGNLGLSNALFIHFANKLTQSRMQRDLSDSTVLRNLGVAFSYSLIAYHSVAKGN-DKLQINKSALQKDLSENWeVLAEAIQTVMrrynepnAYEQLKELTRGQMIDAENLKKFIKTLS-IPEEAKAELmkLTPETYTGLA------------
>UniRef50_Q492R4(12-453:460) Adenylosuccinate lyase n=3 Tax=Bacteria RepID=Q492R4_BLOPB   E=1e-44 s/c=0.41 id=18% cov=59%
---------------------------------------------------------------------------------------------------------------EKITNHDLKAIEYFLKEKINILPNlkkisEFIHFACTSDDINNLAYGLMLTNTKKTVfLPIWKQIINEIKKMSINYKDIPVLSRTHGQPATPSTIGKEMANIAYRLIRQYHQL----KSIKILGKMNGAVGNYNAHVIAYPEINWRKFSEEfvisLGMKWNPYTTQIEP---HDYIAELSDCIARFNTILINFNRDIWGYIA---LNYFKQNHSNTTIGSSTMPYKVNPINFENSEGNLGLANAMFNHFSAKLPISRWQRDLSDSTVLRNLGMAMGYALIAYHSILKG-IKTLTVNKEHV-----------------------------------------------------------------------------
>UniRef50_C2ANG7(21-433:446) Adenylosuccinate lyase n=1 Tax=Tsukamurella paurometabola DSM 20162 RepID=C2ANG7_TSUPA  E=3e-43 s/c=0.43 id=19% cov=67%
-----------------------------------------------------------------------------------------------------------------------------------------VHRGLTSQDVMDTALMMLARRVADEVAEDLAAVSAALARLADEYADTSQVGRTLGQFAVPITFGAKVAGWRQGIDGAARRLAAAGTPVQ----CGGAAGTNAAVVAMGVDPVQAGAQWARKLALTPSEP---WHTSRGPVAELGDALAAVCAAAGRIANDVIQASRPEVGELAESAVDRG--GSSTMPHKRNPVLSVLIRAAALSAPGHAGVLQLAAGQAEDERSTGAWHAEWPALRSLLRLALGTAESLRELCEHLRVFPDRMAQrvtaaaplLVSERLMIVLAERARGGRAAVQAAIDAAVAAPVDDRAAVLREGIsgavpgLTAAELDELLAVDGYLGTA------------
>UniRef50_Q89AM3(59-451:460) Adenylosuccinate lyase n=2 Tax=Enterobacteriaceae RepID=PUR8_BUCBP   E=4e-42 s/c=0.45 id=16% cov=47%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------IKKIALLHHNVPMLSRTHGQPATPSTIGKELINFAYRLERQLKQF----KNIEILGKINGSTGNYNALHFSHSSVDWHKISQEfvtsLGLFWNPYTTQIEP---HDFISEFFSCLARVNTILINFNRDIWGYISLQY----FNQTPKlDEIGSSVMPHKINPIDFENSEGNLGLSNAIISHLIEKLPISRWQRDLSDSTVLRNVGTVIAYSIIAYDSIILG-LKKLKVNTSRLLQDLNH-----------------------------------------------------------------------
>UniRef50_Q8K9Q7(11-449:456) Adenylosuccinate lyase n=315 Tax=cellular organisms RepID=PUR8_BUCAP  E=2e-40 s/c=0.39 id=16% cov=55%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------THGQPATPSTMGKEMVNFYYRMQRQYHKL----KKIEILGKINGTTGNYNAHLVAYPKVNWHAVSKEfitsLGIFWNPYTTQIEP---HDYIAELFGCVSLFNNILIDSNRDIWGYIS---LNYFKQKLIDQEIGSSIMPHKINPIDFENSEGNLGLSNALMNHMINKLPISRWQRDLSDSTVLRNIG---VVFAYSIIAYNSVLLGTnkLTINTSQLLKNLDNNWSvLSEAIQTVMRRytiENAYEKLKK-LTRGKKIEKVDihkfidkLNIPKIEKERLKKI-SPSNYIGAA------------
>UniRef50_C7MHE6(39-464:823) Argininosuccinate lyase n=1 Tax=Brachybacterium faecium DSM 4810 RepID=C7MHE6_BRAFD  E=6e-40 s/c=0.39 id=20% cov=69%
----------------------------------------------------------------------------------------------------------------------------------------DVQLARSRNDLDAGVFRMILRRGILDLAELLLQAVRDLEEAAARTVDALLIGHTHRRPAQPTTIAHVLSGLAEAFLSQAEELLSVYDEMNVSPLGSAAfTGTDIAID-------AQRVADLLGFSSSFTA-SYEAVAGAEHFMRLAGLHARIASTGARWARVL-----QEWMNLGWVRMPdEFTQGSSIMPQKKNPVVLEHLVSMSGAANGETNAVYTTIAAGWYEDSNNATTDVQKHLWSSTERIIRFVRLIDGL--TLEIEPAALpsDEDIVRSGATTTAVAEALAthsvpWRSAHDVVGTLFRQGDPtTWDEGQVEAALAEAAIDDDGRLRDLVLSSGRDPRRILEREQ
>UniRef50_Q2P2F7(10-395:431) Argininosuccinate lyase n=22 Tax=Proteobacteria RepID=ARLY_XANOM   E=1e-39 s/c=0.43 id=23% cov=40%
-----------------------------------------------------------------------------------------------------------------------------------------IHTGRSRNDQILVATRLWLKDKLQRVATLSAEIAKVALDRAQAEAELPVPGYTHIQRAVVSSAGMWWAGWAEAFIDNAVRATDTLQLVDSNPLG-TAAGYGVNLPLD-----RAHTTAELGFARLQVSPIYAQLSRGKYELAALEALGSATLDLRRIAWDVSLFTS---GEFAFVALPAqYTTGSSIMPNKRNPDVIELM----------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A3VZD3(22-340:357) 3-carboxy-cis,cis-muconate cycloisomerase n=4 Tax=Alphaproteobacteria RepID=A3VZD3_9RHOB  E=7e-39 s/c=0.51 id=16% cov=40%
-----------------------------------------------------------------------------------------------------------------------------------------VHQGATSQDVLDTALALTLQATTKLLDHRLASLQSALADLDTRFGSNPLMGRTRMQAAMPIRVTDRLRPWITPLTTHRSRLARATDGVALLQFGGAA------GDRAAMGADAPRIAAHLAAALGLGNPPTCWHATREGLADYASTLSLISGTLAKMGQDVALMAQQGIDEIHLT----GTGTSSAMPHKQNPILAELL----------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A8NWV8(45-385:443) Adenylosuccinate lyase, putative n=1 Tax=Brugia malayi RepID=A8NWV8_BRUMA  E=3e-36 s/c=0.45 id=24% cov=41%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AEKTKDIVTVGRTHYQTASLVTVGKRAAMWAQELLMVFTKLEHFRENMRFRGVKG-ATGTQdsfmalFHNDEAKVDKLDELIMKSAGFASRFY--ISGQTYSRQQDCDLVNIFALLGAATKKICTDIRILQA--FGEVFEPFESE-QVGSSAMPYKRNPIKSERVSSLARKLMSAP----------------------------------------QHIVEGLTVDKERIEYNVHADL-------PFLALEKAMML---------------------------------------------------
>UniRef50_UPI000187E7E3(3-221:282) hypothetical protein MPER_06834 n=1 Tax=Moniliophthora perniciosa FA553 RepID=UPI000187E7E3  E=1e-34 s/c=0.68 id=20% cov=33%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ARDGIAECVSFLSIIGGTLGKIALDLLLLSSSEFGEVQEPFVPHR-GASSTMPQKRNSISSEVILA-CSKLLRQHASTAQDAMVSDLERASGPWHLEWSCVPEAFCAASGALKQTEFVLDGLVVDTQRMLQNLDMSKGLivgeaiMMGLAPSLGRNAAHDVVYEA-----------------------------------------------
>UniRef50_A9DHF9(21-345:352) 3-carboxy-cis,cis-muconate cycloisomerase n=1 Tax=Hoeflea phototrophica DFL-43 RepID=A9DHF9_9RHIZ  E=4e-34 s/c=0.46 id=17% cov=40%
------------------------------------------------------------------------------------------------------------------------------------------HFGATSQDLVDTATIETLAKTISILSKRLDQLITALEAMTARDGNNALKAITRMQEALNIRASSRLAGWRLPLEALRDRLPAVREQVMVLQFGG-AVG-DLQTLSDDADTVAKAIASDLGLRWPGHSWQ----TSRAPLIAAASWMTELSGALGKIGQDAAIMALRGKSDLEL----SGGGTSSAMPHKQNPVAAERL----------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q92PB6(2-463:463) Fumarate hydratase class II n=16 Tax=cellular organisms RepID=FUMC_RHIME  E=1e-129 s/c=1.01 id=38% cov=96%
-----RTETDTFGPIEVASDRYWGAQAQRSLGNFKIGWEK--QPLAIVRALGIVKQAAARANMALGRLDPAIGDAIVKAAQEVI-DGKLDEHFPLVVWQTGSGTQSNMNANEVVSNRAIELLGGVMGSKKPVHPNDHVNMSQSSNDTYPTAMHIACAERvIHDLLPALKHLHKALEEKVKAFDHIIKIGRTHTQDATPLTLGQEFSGYAAQVASSIKRIEMTLPGLCELAQGGTAVGTGLNAPVGFAEKVAEEIAAITGIGFTSAPNKFEALAAHDSMVFSHGAINATAAALFKIANDIRFLGSGPRSGLGELSLPENEPGSSIMPGKVNPTQCEALTQVCVQVFGNHAALTFAGSQGHFELNVYNPLMAYNFLQSVQLLADAAISFTDNCVVGIEAREDNIKAALDRSLMLVTALAPKIGYDNAAKIAKTAHKNGTTLREEAVGGGYVTDEEFDAVVRPETMIGPA------------
>UniRef50_D2Q852(18-479:494) Aspartate ammonia-lyase n=2 Tax=Bifidobacterium dentium RepID=D2Q852_9BIFI  E=1e-117 s/c=0.92 id=48% cov=96%
-----RIEHDCIGSAEIPAEAYWGIHTLRAIDNFPVSGITVSDHPELIRAYAQVKQACARANGELSNINAYQAALIDRACEDV-ASGELNDQFPVDVLQGGAGTSTNMNVNEVIANRALELGHHARGEYDIIHPNDTVNKSQSTNDTYPAACRLALIGASGMLVDRTSQLVDAFHTLSERTMPIVKIGRTQLQDAVPMTFGQEFGGFASQLDADARLLSSQQTPLAVVNLGGTAIGTGICADARFRERAIRHLAELTDLPIRAADDSVGATSDVGDFVTLSGAIKRTALHLGKIANDLRLLASGPRAGFEEIHLPARQAGSSIMPGKVNPVIPECVNQCVFMIMGMDATISCAAEAGQLQLNAFEPVMLHALLTGMHTLANAMDTLREHCVSGITVNEQAGMDEVMRSSSLATALIGYIGYERAMTIAQEALVRNTTVREIAQKEKVLSPELLDSILDPHNLTH--------------
>UniRef50_B1MWT6(1-457:477) Aspartate ammonia-lyase n=6 Tax=Lactobacillales RepID=B1MWT6_LEUCK   E=1e-117 s/c=0.93 id=47% cov=96%
----MRIESDSLGQLNIPQSTYYGIHTQRALNNFPIS--KASTHPELIRAFIEIKQAAAQTNATSGNLNRSVAKHIVSATKILLNQPIDTTMFPISDIQGGAGTSTNMNVNEVIANLALEKVGRQRGDYQFIHPNDHVNMGQSTNDTYPSAGKIALIRLLAPLLNELTQLIDALGNKADEFSTTYKMGRTQLQDAVPMTLGNSFHAWLKPLLRDNLRIQSARDSLYYLNMGGSAIGSGINVSYHYQVHIVPNLAGITKLPLKQAHDLFDATQNLDSFVALSGTLKTLAVNLSKIANDLRLLSSGPRSGLLEINLPAKQAGSSIMPGKVNPVIPEVVNQVAFEYFGFDATVTAAAEAGQLELNAFEPIVFKSLFTGIEHLTAAMATLRINAIDGITSNKNRLAQDIDLSVSFATAMAPIVGYQLAAKMAKESLRTGKSLRQIAEKKNCFTPEELAHIFKVEDIV---------------
>UniRef50_D2LUT1(3-460:460) Fumarate lyase n=1 Tax=Bacillus cellulosilyticus DSM 2522 RepID=D2LUT1_BACS4  E=1e-114 s/c=0.90 id=42% cov=96%
-SNEYRTERDPLGKVKIPKRAYYGSQTQRAIENFQISNKHL--PRSFIKAQGIIKVAAAKVNIDLGMLTKNLGEAIITASEEVI-NGEWDDQFVVDVYQAGAGTSQNMNANEVIANRANEILNKGTHA-ERIHPNDHVNMSQSTNDTFPTALNIAALEGIHEsLIPAIDQLQQALNRKSEELMSVLKSGRTHLHDAVPMKLGQEFAGYAETIRSLYEEIKQNSEELYEIGLGGNAIGTKVNLHESYAKKVIAEVSKRTNYPFREPTNIFSFMQNRNAPLRVMGSLKELSVHLIKITSDLRLLSSGPRTGLAEITLPSVQPGSTIMPGKVNPAILEMTHMVCCQVIGYESTLSTAVMSGQLEINVMMPIIAYTLLESIHILANAITSLVEKCITGIKANEATCRKWMEESLSLVTGLSPSMGYDLASEIGQQAEEENKTIKQILIDKGLNTKENI-SAIDPSNFI---------------
>UniRef50_C7RF85(2-454:454) Fumarate lyase n=2 Tax=Anaerococcus RepID=C7RF85_ANAPD   E=1e-114 s/c=0.91 id=39% cov=94%
-----RIERDSLGEIEVDNDKYWGAQTQRSFMNFPKGLDLMPKEE--IRALTLIKKAAAIVNFELGKIDEERKNLIVYAADRIL-DGDFDDQFPLTVWQTGSGTQSNMNVNEVIAHIANEKCGENL-----IHPNDHVNKSQSSNDTFPTAMHMAsLNLLENELLPEIDEFIGGIESKAKEFEGIIKTGRTHLQDATPIALSSEIRAYSEIIRRDKAALIDLMEDLRRLPIGGTAVGTGLNAPEAYSSKMISTLEKLSGLRLIEDSNKFVGLSSKQAMARVHSALKVLAEDLNKIANDLRFLSCGPRTGIGELILPTNEPGSSIMPGKVNPTQVEMMTMVAIQVMANDTAISIANASGQLELNTYMPLVIYNMVKSIKLLTKAMTSFRIHLIEGLVANKEKIEENLDKSLMLVTSLSPLIGYDKAAELAKFAHKNNLSLREANKELGFVSDTDFVKTVDPREMI---------------
>UniRef50_C8P033(5-454:455) Fumarate hydratase, class II n=1 Tax=Erysipelothrix rhusiopathiae ATCC 19414 RepID=C8P033_ERYRH  E=1e-111 s/c=0.90 id=34% cov=94%
--------EDKFGKIDIPEGALWGVNTQRSLQNFPIGQET--MPESLIEALIVLKKVSAKVHRVHHKMDEDIAKVIVEACDYLL-DGDLKEAFPLSIWQTGSGTQTNMNVNEVIAHLANTRFHG-----HHVHPNDHVNQGQSSNDIFPSAMHISTVLLVKnSLMLSLEDMIETFDALIDQYGLVMKTGRTHLQDATPITFGQELGAWRHMYQEGLDQLNQCLESLQPLAMGATAVGTGLNSYEGFDQAICDELNQMYHESFRPSVNKFHAISSKDSFVFLQGALAAIASNSLKMANDIRFLASGPRCGLGEISMPENEAGSSIMPGKVNPTQCEALMMVCAQVMGNQTAVTVGAALGNFQLNTFMPLIIHNTTQSICLLSDALNSFNLRCLQGIEVDKEKMSDNLHKSLMTATFLNRKFGYDHTAKIVNQAHQEGKSIKTVVVESGAMGDDEFDAFFDYQKMIQP-------------
>UniRef50_Q58339(17-446:462) Adenylosuccinate lyase n=23 Tax=Euryarchaeota RepID=PUR8_METJA   E=1e-106 s/c=0.90 id=22% cov=87%
-----------------PIDYRYGTPEMR----------KVWEEENKLEKMLKVEAALAKAQAELGLIPKEAAEEINKKASTKYVKLERVKEI------------EKQTKHDVVAMI------RALAEVCEGNAGEYIHFGATSNDIVDTANSLLIKESIEIIEDKLKQLRDILLDKAEEHKYTVCVGRTHGQHAIPTTYGMRFALWAAEIDRHLERLKEAKKRICVS-MITGAVGT-MAAMGEKGLEVHKRVAEILGLEPVLISNQVIQ---RDRHAEFVFLLALIAQTLNKIGVTVRSMQRTEIGELEEEFDPTKQTGSSTMPHKRNPITFEQICGLS-RVIKSLCIAEMDNIPLWEERDLTNSSAERCIFAEVCVLTDHILTLAIKGVKKLKVNKENVERNLELTKGLIMAERimielakRGMGRQTAHEIVRQcamkAYEEKRHLKDILLENeevmKYITKEELEELMNPKTYIGLA------------
>UniRef50_C0EVA8(1-450:470) Putative uncharacterized protein n=1 Tax=Eubacterium hallii DSM 3353 RepID=C0EVA8_9FIRM  E=1e-100 s/c=0.82 id=40% cov=89%
----MRLEKDTLGEKYLTDETVYGINTQRAVENFPLSHKKVNLH--LIHAMLLVKKAAAKTYENLvEDIEKEKYQAIVAACDELLLKTEEdksfsqqaehnrdnqnqaednrrgiDALFVTQALQGGAGTSTNMNVNEVIANIALKHLGKNYGDYNCIHPLDDVNRGQSTNDVYPTALRIASIFLIRKLSDACAALQTSLQEKENAFQDIEKLGRTEWMDAVPITLGEEFGACAQAIARDRWRIYKVEERLRQVNLGGTAVGLSDNAQHKYRFRVIEELRRLTGLGLAAAEYPMDLTQNNDVFVEVSGLLKALAVNLMKIANDFRIMNSGPGGGIGELHLKAMQQGSTIMPGKVNPVIPEMTMQCAMRIIANDTAITMAAAHGEFELNAFLPLIADSLLESLELAERAVTIFREKCVETIEPDVENCKKHLEQSYAFATAYTPKLGYETVAKIIKE------------------------------------------------
>UniRef50_B3T9V2(8-433:489) Putative Lyase n=1 Tax=uncultured marine microorganism HF4000_APKG7H23 RepID=B3T9V2_9ZZZZ  E=3e-86 s/c=0.75 id=22% cov=87%
----------------------YTTHTFQSASHYTVSVGYDRRLASYdIRA----SVAHAQMLARQEIIPQSDSDAIVRGLGEVHQEMEDGTFPWRDELE---------DVHMNIERRLHELIG---------EPAARLPTARSRNDQVATATRLYVRDAIEATMARVHRLQGTLLDLAEAHATVLMPGYTHLQRAQPVLLAHHLLAYVEMLERDTGRLADCLSRANVLPLGSGALaGVPYAIDREF-------LARELGFETVSA-NSMDAVSDRDYLVELLASASICMMHCSRMAEELVLWSSQ---EFGFIRLgDEWITGSSMMPQKRNPDFAELARGKTGRVYGHLVGLLTVLKGLPLSYNRDLQEDKEALFDTVETL-DATLEVFAGMLGSVEVNAERMRSAAEDGSLLATDLADYLvskgvPFRTAHAAVRglceLAAQDGRPLQELTLEEYRRFSPAFDaDVFQLTALTSVAARA---------
>UniRef50_C1DFC3(17-448:452) Adenylosuccinate lyase n=1 Tax=Azotobacter vinelandii DJ RepID=C1DFC3_AZOVD  E=1e-85 s/c=0.74 id=18% cov=84%
-----------------------------------------------------VEAALAKVQGELGIIPRAAADEIRRKAR--------VELIDLGALKAEMDRTAHPIVP----------LLRAIKRVCDGDAGEYVHWGATTQDIVDSGTVLQLRDGLEEIERDLRGLLDNLLKLAATHRDRVMVGRSHGQQALPITFGFKVAVWAEEIRRDLQRLDQMRERVLVGQF-AGAVGT-LSALGEHGIAVQEGLFRELGLGCPSIAWHV----SRDSLAELASVLAIATGSVGKIAHEIYALQKTELGELEEPFSP-GKVGSSTMPHKRNPAACETVVALA-RVVRSIVPLALEGVLAEHERDKIVLQTEREYLARLFGLSHAAIAKTRAIAAGLTVRGAHMEENLYRqrglllSEAVMMRLSDALGRQEAHEIVYricmEVFEREGTLKEALLADPLvgdrLSPEEIDALLDPKAYTGLAGAFVDRVTARRQ
>UniRef50_A6UW73(15-457:487) Argininosuccinate lyase n=12 Tax=Euryarchaeota RepID=ARLY_META3   E=2e-85 s/c=0.72 id=23% cov=65%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNDEVATDLRMALRDKILTILKLLINMQKNILNLAKEHKETLTIGYTHLQHAQPITFGHHLLSYASPMERDILRLIDTYKRVNICPLGSGAFAtTGFNINRNATK-------ELLGFDSV-IENSMDGVASRDFILETMANLSILGTNLSKICEEMVLFSS---CEFGTIDLAnEYTSTSSIMPQKKNPDVAEIARAKLSTLNGNLVTVLTILKALPNTYNRDLQEISPHLWDSVYTTIDTLKII-DGMISTIKVNADRMKELTEKNYSTATELADTLVREcnipfrtahgIVGEVVRLSIENNKNMNEVIRDvldkfNLKLDDSKIEKALNPME-----------------
>UniRef50_Q2JXY9(48-440:489) Argininosuccinate lyase n=52 Tax=Bacteria RepID=ARLY_SYNJA   E=5e-83 s/c=0.79 id=22% cov=66%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNDQVATDLRLYLRDEIDTIRQALWELRGVLLDLASQHVETILPGYTHLQRAQPISLAHHLLAYEEMLWRDWQRLGRVREEVNVCPLGSGALaGTSLPIDR-------QLVAHLLGFERISA-NSLDAVSDRDYLVEFHAAASLILVHLSRLSEELILWATQ---EFGFVALtDACATGSSLMPQKKNPDVLELVRGKTGRVFGHLQALLVTLKGLPLAYNKDLQEDKEGLFDTVDTVKACLEAMTILLREGIQFQTQRMEAAVQEDFSNATDVADYLvrkgipfraAHDLVGQIVRTCVAEGILLKDLPLERwksfHRAFEEDIFAAIDPRQVV---------------
>UniRef50_Q9X0I0(2-418:431) Adenylosuccinate lyase n=11 Tax=Bacteria RepID=PUR8_THEMA   E=2e-82 s/c=0.74 id=17% cov=65%
------------------------------------------------------------------------------------------------------------------------------------------HYGLTSSDVLDTANSLALVEAGKILLESLKEFCDVLWEVANRYKHTPTIGRTHGVHAEPTSFGLKVLGWYSEMKRNVQRLERAIEEVSY-GKISGAVGNYANVPPE----VEEKALSYLGLKPEPVSTQVVP---RDRHAFYLSTLAIVAAGIERIAVEIRHLQRTEVLEVEE-PFRKGQRGSSAMPHKKNPITCERLTGLS-RMMRAYVDPSLENIALWHERDISHSSVERYVFPDATQTLYYMIVTATNVVRNMKVNEERMKKNIDLTKGLVFSqrvllklIEKGLTRKEAYDIVQRNalktWNSEKHFLEYLLEDeevkKLVTKEELEELFD--------------------
>UniRef50_B8FH31(6-434:465) Argininosuccinate lyase n=8 Tax=Bacteria RepID=ARLY_DESAA   E=3e-81 s/c=0.71 id=21% cov=70%
--------------------------------------------------------AHARTLAEAGVITSDEADAMEKGLRQVKGEIEAGNFKYDDSLE---------DIHMHIESRLTEILGPTAAK---------LHTGRSRNDQIALDNRLYLRDETRRIIAMLHELRQAIVDSAQAHLDYFVPGYTHLQRAQPVLLSHHLMAYYEMFTRDSDRFTDALYRINVMPLGSAALaGTTFPLDREYT-------ASLLGFEGVT-QNSMDAVSDRDFIMEFLSDASICMVHLSRMSEELVLWSSS---EFAFLNMPdAFATGSSIMPQKKNPDVPELVRGKTGRVVGSLMAILTTMKSLPMAYNRDMQEDKPPLFDAVDTL-KACVAMFARMVPKLEFNRRNMFDASNQGFLNATDMADYL-----------------------------------------------------------
>UniRef50_O28041(5-430:444) Adenylosuccinate lyase n=5 Tax=Euryarchaeota RepID=PUR8_ARCFU   E=1e-79 s/c=0.70 id=20% cov=86%
-----------------PIDYRYGTPEM----------KRIWSEDSKIKRMVRVEMALLRALAKKGYLSEEEAKEAKKKAYSVTPE----------------------RVKEIEAEIKHDIMALVKAITEATGC-RWVHFGATSNDIIDTATALQLRDSLKILEVKIKRLAKVLADKALEYKDVVCLGRTHGQAALPTTYGFRFALWAAEVARHYIRLQQMKDRLLVGQM-SGAVGTQ-AAFGKDGFEIEEEVMRLLNLKPALISSQIIP---RDSYCEYLEFLANLAATLEKIALNFRLLQRAEVGELME-KFEAKQVGSSTMPHKRNPIDCENVCGLA-RVVRGFVEPQHQSAILWEERDLTNSSAERITLVESTVLADHILTKMIKVVSSVSLNLENIRRNLEMQRGLNLSEAvmiemtkRGVGRQEAHEILRqaamRAYENNSSLLDELLKDervmKYFKEDELREILKPENYLGTARE----------
>UniRef50_C3MRJ0(24-447:468) Adenylosuccinate lyase n=14 Tax=Thermoprotei RepID=C3MRJ0_SULIL   E=1e-79 s/c=0.71 id=18% cov=86%
-----------------PLEWRYGSNEMR----------KLFSRGEILKRRIQVEIALLKALSKYGLVKEEDIQKVEKASLTIRPEE-------VDELESKIG-------HDVMAMVV--LMAERSG-----DSGRYVHFGATSYDIVDTAYALIFRDAIRLVKRKIMEILEIMISLAIKYKDLVMVGRTHGQHALPITLGFKIANYIYEFSRSLERLNEVEKRI-VKGKIAGAVGT-MAAWGNIGLEIEENIMKLLELRPHEIST---QVAPRDAFAELTSDLAILASQCDRFALEVRELMRPEINEISEGV--EGRVGSSTMPQKENPVTSEKIGGLA-KVLRSLVVASLENIPLWHERDLTNSSSERIVISHEFLIIDEILDSMTNLLRNLRVNFENIEKNLNLTKGQIMAESlminltlKGMKRHEAHQYVNkltsKVRQTGKTLLEVCLEDnlilSYFSKQELENVFNPKNYLGS-------------
>UniRef50_A1TS34(11-448:452) Adenylosuccinate lyase n=2 Tax=Proteobacteria RepID=A1TS34_ACIAC   E=6e-79 s/c=0.68 id=17% cov=85%
---------------------LWGTDELR----------TIFGEENRVQKWLDFEAALAAAQAEMGIIPAAAAREIAEKARvENIDIAKMSAEI------------------RRIKHSLVPAL-RQLQAACSRENGEWVHYGATTQDVVDTGVALQLKEFHAVAMRDLQAVGRELARLAVAHRDVPMAGRTHGVQALPITFGHKCALWLDELGRHHERLVQAAPRV-LVGMLAGAVGSQASLGP-KAIELEERMLGKLGLGVPAISWA----PARDRFAEYTNLLAMLGSTLSKIGNELFNMQRNEFGEVEE-GFSEGKLGSSTMPHKRNPTSAENLAGLS-RPLRYNAAMMVEGMVSESERDGIAWKMEWKAVPECCMIAGAMLFQAKNLLAGLKVNADVMAANLDKmrgyllSERVMLELSERVGKQTAHEWIYEASMHGIThklgFADAMRQHKglgeLLTDAEIQDLTDPAGYLG--------------
>UniRef50_C0QEF7(3-438:442) Fumarate lyase (DEAD box) n=1 Tax=Desulfobacterium autotrophicum HRM2 RepID=C0QEF7_DESAH  E=5e-77 s/c=0.67 id=29% cov=90%
---------------------LYGEETKKALILFGPGQ----TAREMIRAYGEVKLAAIRAQQEsSGLYPGDYFPLLEETAKEII-EGQLDAQFPLPLSQGGAGTSFHMNLCEVLSEGTNRKYKGDFKA----HPLDHLARFQSTNDTFPTAVTLMTFRYLEQVEQKVVCLQEQLVSRETLYEEWLMCGRTELQDALPMTLGQLYSAWAGPVERDRWRLNKLKERLRTIPLGGTAIGTGYSAPRNYVFSAEKHLRRITGLPLCRSQNLCDQVAHTDNLAECAAGLGLCADNLYKMCSDMLLYSSSLS---GEIRHKEMQYGSTIMPDKSNPVLLELIRGLSMECASSAALIREYSRSGQMQLNANLPFLAEQMIRLFHSLTRALDCAAGPLMDALEPDREKMEARLAVSPALLNTLKDVLGYSRLKELIPRIKAASPSNRDALIlwlnQNTGLSKAFLHDKFNYFNLTG--------------
>UniRef50_B8IZS3(18-436:466) Argininosuccinate lyase n=1 Tax=Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774 RepID=ARLY_DESDA  E=8e-77 s/c=0.69 id=20% cov=67%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNDQVGLSFRLFVADRLETWRQRAAALCAILVQRATEHAGDILPGCTHLQPAQPVSLAHHLLAYAWMFRRDAMRLGDCLDRVRISPLGAAALaGTTYPLDP-------QSVAKDVGFDG-IYGNSMDAVSDRDFVLEALFGGSTIMMHLSRLCEEIILWANPA---FGFVRLPDsYSTGSSIMPQKKNPDVAELMRGKTGRVYGSLMGMLTIMKGLPLAYNRDMQEDKEGFLD-ADRTVEASLRLMAGMMEEIAFRTDRMREACKAGFLNATELADYLvgkglpfreAHHVTGQCVAAAEKQAKGLEDLTLPEMQALEPRIGE--DVYAILDYAAAVQRR------
>UniRef50_C8X3L5(3-433:470) Argininosuccinate lyase n=2 Tax=Desulfovibrionales RepID=C8X3L5_DESRD  E=3e-76 s/c=0.67 id=18% cov=85%
------------------EQKLWGgrfeARTDSLVEQYTASVETDKHFA--VQDIAGSK-AHAAMLAAQGILTREEAQTLRNGLDQVADEILQGSFEWRDDLE-----DVHMNVEKRLTDIV-------------GETGQKLHTGRSRNDQVALGFRLLVSERVTAWQGHLCGVIQALVEQARQHVQTILPGYTHLQPAQPVSLAQHLLAYATMFQRDWERLNDAQKRIRVSPLGAAALaGTTYPLDP-------QAVADELGFETVFA-NSMDAVADRDFVLEPLFGASCIAMHLSRLCEEIVLWANP---GFGFVRLPdAFATGSSIMPQKKNPDVAEIMRGKTGHVYGALMGLLTTLKGLPLTYNRDLQEDKAPFL-EADRTVGLSLEIMARMVPELEFLPEPMRRATRAGFLNATEFADYLvgkglpfrqAHHITGQAVAAAERAQCGLEDLSLAQfrefSPLVDEDIYAVLD--------------------
>UniRef50_Q5HT21(16-437:455) Adenylosuccinate lyase n=22 Tax=Proteobacteria RepID=Q5HT21_CAMJR   E=1e-75 s/c=0.68 id=18% cov=82%
-----------------------------------------------IQKWLDVEAALAKAQAKLKIIPKKAADEIAKKA--------HYKFMDMDFIFAEYKKTKHPLVPTV----------RGLEKACDDNLGEYVHFGVTTQDVIDTGLVLQFKEAMILVKSELKAIAKALAKLAKTHKNTAMMGRTLALQALPITFGHKVAIWLSELDRHFERILELEKRLYVGSIVG-AVGTKASLSDECNE-VEKLTLENLGLDVPNISWQ----PARDRFIELGFVLGNINATFNKIAHEILILSHNEIDEVAE-PFGKGQVGSSTMPHKRNPAVSENAVTVSNAFKANL-AILSDIERHEHERDGQVWKMEWKLLPEMFLMLSVVLANMKFALSDLEVKKDKMLKNLNtlNGFVLAErvmfALSDHYGKQHAHEIVYENAMLGiekqKTFKEVLLADKRVSkvlkEKEIDALLDASTYVG--------------
>UniRef50_B0T2T7(36-433:455) Argininosuccinate lyase n=9 Tax=Bacteria RepID=ARLY_CAUSK   E=2e-75 s/c=0.72 id=21% cov=67%
------------------------------------------------------------------------------------------------------------------------------------------HTARSRNDQVAVDFRLWVREACDRSAAQLEALQKALVAQAEQYADALMPGFTHLQPAQPVTFGHHLMAYVEMFGRDASRFRDARVRMNECPLGAAALaGSPFPIDRH-------ATAASLGFD-RPTANSLDSVSARDFALEALSAASICATHLSRLAEEIVLWTTP---MFGFVKLtDAFTTGSSIMPQKKNPDAAELVRAKVGRILGSLTTLTVVMKGLPLAYSKDMQEDKVPTFEAFDALELSLLAMA-GMVSDLTPNTEKMAAAAGAGFSTATDLADWLVRElnmpfrDAHHVtgsaVKAAETLGVDLAELSLADLRAIEPRITS--DIYTVLTPAASAASRI-----
>UniRef50_A3EQW2(9-462:467) Argininosuccinate lyase n=3 Tax=Bacteria RepID=A3EQW2_9BACT   E=3e-74 s/c=0.62 id=18% cov=86%
------------------SEKLWGGrfsePTDREVEMFTQS---ISFDRALWRQDIKGSRAHAAMLLKVGLLAHEEERRIQEGLSRIEEEMTNGTFPYRDEYE---------DIHMNIEKRLFELVG---------TPAQKLHTARSRNDQVSLDLRLYVIDRSREMAGLLAEFIRVLIGQSRRMRDLILPGYTHLQQAQPISAGYYFMAHAERLLRDRQRFLEIDRRLNLSPLGSGALaGTTLPIDR-------NHVARSLGFSGVTG-NGLDAVSDRDFVADFLHAAVMLSLHLSGWAEEWILWST---REFGFVRIPDRYmTGSSMMPQKRNPDVLELIRGKTGRVIGHYMGLATILKGLPLSYNRDLQEDKEHLFDAAETVRQSV-TLFSRIAGESVLDGERLREALSGDELLATDMAEDLVREgvpfreahaIVGRIVAYCERERRKLASLTDEElrtfSPAFPEQYARVLTPEN-----------------
>UniRef50_Q66J94(6-412:443) MGC81570 protein n=4 Tax=Euteleostomi RepID=Q66J94_XENLA   E=2e-73 s/c=0.69 id=21% cov=75%
-------------------------------------------------------QAYVKALEKAGLVSKSEMEQIISGLDKIHDEWS-------------SGTFVLTKGDEDIHTANERRLKELIGE-----VAGKLHTGRSRNDQVVTDMRLWLRDSCSTLYTHLTRLIQTMVERAAIEVNILFPGYTHMQRAQPIRWSHWILSHAVALSRDAERLGEVKKRVNVLPLGSGAIaGNPLGVDR-------ELLCK----------------------AEFLFWASLCMTHLSKMSEDLIIYSTK---EFGFVTLsDSYSTGSSLMPQKKNPDSLELIRGKTGRVFGRCSGFLTTLKGLPSTYNKDLQEDKEAMFDVYDTVC-AVLQVASGVIATLQINKEAMEKAL-SPDMLSTDIAYYLVRkgmpfRQAHgvsgKVVQLAETKGMSVDKLTLENlKSISPLFSDDVSKVWNYTNS-------------
>UniRef50_A9IZG7(30-417:466) Argininosuccinate lyase n=23 Tax=Bacteria RepID=ARLY_BART1   E=2e-73 s/c=0.72 id=24% cov=56%
------------------------------------------------------------------------------------------------------------------------------------------HTARSRNDQVAVDFRLWVRETLQKIAQALKQLIKQLLILAEQHVKTYMPGFTHLQLAQPVTLGHYMMAYVEMFGRDLSRMRDASERMNESPLGAAALaGTSFPIDRFMT-------AQALGFR-EPTRNSIDSVSDRDFALEFLSAGALCAMHLSRLAEEIILWSSEQ---FRFIYLsDAFSTGSSIMPQKRNPDAAELVRAKTGRLNGALMGLLTVMKGLPLAYSKDMQEDKEYVFDGALSLELSLAA-MTGMIADLEVNKKAMKQAADLGYATATDFA--------------------------------------------------------------
>UniRef50_A7IQF6(21-431:456) Fumarate lyase n=3 Tax=Xanthobacter autotrophicus Py2 RepID=A7IQF6_XANP2  E=8e-73 s/c=0.67 id=17% cov=76%
----------------------------------------------------------AEVEGEFGLIPETSAAAIVAACRDVVLDDDFFARFAAGYRATGHSTAG---------------LIDVIRQRYPESVSEWFYFGATVQDITDSWLMLVLGEARALILADLDRSIAAATALCRAHRDTVMVGRTHGQQGLPITFGFKVAGWLAELRRHRQRFEEIAGRMGIGQLCGG-VGSLSALGRH-GLEVQRAFCERIGLRPPLTSW----TASRDVLVEWAQLLTLVAGTADRIGHEVYSLQRDEVGEVREGAAGE-QIGSITMPHKRNPEIAEHL-GTLSRVVRANTSVLAESLPHDHERDGRSWKLEWHAVPELTMAAGKAVRLLGQMLSNLEVRADRMHANLEAcdgriySEGLMLALACKLGKQTAHRLVHQAAgragQEGQAFREVV------------------------------------
>UniRef50_Q1YSL1(37-453:475) Adenylosuccinate lyase (PurB) n=1 Tax=gamma proteobacterium HTCC2207 RepID=Q1YSL1_9GAMM  E=2e-72 s/c=0.66 id=17% cov=83%
-----------------------------------------------VQRLLDIEAALARVQADLNIIPDWAAEELTRKAQ--------VSNVPLDQLkEERARVRHSMVSLLNIWQHSIE-----------GGAEEYMHYGATTVDIFNTAMVLQLYDASAVLLDQLRLLENIMIGLADEYKATPMIGRTLGQHALPITFGKKVSSWLGENRRNIERLKAVRTQIAQSTIMKGAVGSYLGL-GDKGMEIERGVARELGLKAPIVS---DWHPARDVFADYALTLALISKSYGRIGNELFLLNMTDIGETEEI-LPETAVGSSTMPHKKNPKVPDKLIHYSRFIPRLAEVILDDVVNS-FERDD--SSGARVVVEEITKQAASMLEDAFYALSNLTVKTSQMKANLEKTRGLIMtqrltfALADKIGKTTAntrmHELALLALNTNITLREAIELSPDIaqhfSKKKLDELLDAKTYLGLAVE----------
>UniRef50_C8WK16(37-460:461) Adenylosuccinate lyase n=12 Tax=Bacteria RepID=C8WK16_EGGLE   E=6e-72 s/c=0.65 id=22% cov=67%
-----------------------------------------------------------------------------------------------------------------------------------------VHYGMTSSDLGDTALSYQITQAIDIILEDIKQLGETCKRRAFEFQETLCVGRTHGIHAEPMTFGMKFGSWAWALKRAQTRMEEARK-VAATGAISGAVGTYSSIDPF----VEQYVCERLGLAADPLSTQVLA---RDRHAQVMAGLAVTASTLESIAMQVRLLQQSDVIE-AEEPFAKGQKGSSAMPHKRNPITAERVCGLARTVKSN-AQVAFDNVALWYERDISHSGAERVALADSFIALDYMFGKMQWMLDGLQTYPAKMEHNLWRTKGLIfsskvlLALVDtGISREDAYVIVQRNAMKvwediqnavdGPTYRENLEADpeANLSAEVLDEIFDPWDFLT--------------
>UniRef50_Q5WHY3(32-463:498) Argininosuccinate lyase 1 n=1 Tax=Bacillus clausii KSM-K16 RepID=ARLY1_BACSK  E=1e-70 s/c=0.62 id=18% cov=66%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNDILATVTRMRIREEMLEIYELVCTLRRTLIDLATEHTSTLMTGYTHLQPAEPITFAHYLSALLHGFERDFTRLYNCYAHINKSPLGSCALAsTTFSINRKFTM-------ELLGFA-DLLENSLDGIASRDYALEALSALSIFSNSLSRFAQDLYTWCSYEFGYLEVGH--SVAVISSIMPQKKNPVTLEHIKAKAGHIQGALVSSLSVLKNTLYSHSRDTSMESMKYTWEAINETKAAIRLMIKTLQTLTVHKDNMAATTRQNFSTVTELANALvrhyhfsfrtAHHIVAEIVNETLNQGlgsdkieastveRAIKQVTAKTVSVTKEFVEQALDPER-----------------
>UniRef50_B1L6M1(5-437:456) Adenylosuccinate lyase n=1 Tax=Candidatus Korarchaeum cryptofilum OPF8 RepID=B1L6M1_KORCO  E=4e-70 s/c=0.62 id=18% cov=87%
-----------------PIDSRYGSELMRA----------IFRQENRIKLMARVEALYARALAERGFIPKEAAEAIERAAEEVTPEDVRAEEALVK--------HETMALVRAISKRA-------------GRYGEYLHLGLTSNDVLDTVMGVQIRQAGSIILRSSASLLEKIVKRGEESLDIVCLGRTHGVVADPIPLSMKFALWSYYVRRSIARFMDSLNEASVGKLRG-AVGTAAAsieLGIKDPLEVESEVLAALGLSPPEITTQVVP---RDRLAHLILSMSLFSSALDTIANEIRNLHRTEISEVKE-HFEERQVGSSTMPHKMNPINSEKVCGLA-RLMRSLAIAALENVVLEHERDLTNSSVERAILPEAFLILEEQINTLSAVIENLEIDRVRIGENLEKygdialsERLMIWLVKKGLGRQEAHEIVRsislRSHRSGRRFIDEVLADeslsKILRPEEIEAIFSPRSYLGLGRE----------
>UniRef50_Q2PYG7(24-434:459) Argininosuccinate lyase n=1 Tax=uncultured marine bacterium Ant4E12 RepID=Q2PYG7_9BACT  E=3e-69 s/c=0.64 id=24% cov=66%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNDQVANDVRLFVKSEVDDLVSLAFELIAVIRTRAEEaHAEgIYLPGYTHMQQAQPVSLAHHLAAYCWMLLRDVDRLKDAKRRTDVSVLGAGALaGSSLPLNPAFT-------AADLGFD-QLFENSLDAVSDRDFVADVLYALTTLGIHLSKLGEELVIWASS---EFAFITLdDAFSTGSSMMPQKKNPDIAELARGKAGRLIGNLTGFLATQKGLPLAYNKDLQEDKEPLFDSCDTARLTLLAL-RGMIQTLDFNAEAMKLAADSPYAAATDLAEYLveqglpfrdAHALVGGLVRDSLAGAKSFAELVRDHPNLGHEA-------QKLLEPGASYQRRK-----
>UniRef50_C7LJX3(3-376:376) Putative fumarate hydratase n=1 Tax=Candidatus Sulcia muelleri SMDSEM RepID=C7LJX3_SULMS  E=3e-66 s/c=0.68 id=38% cov=78%
----FRIEKDSLGTIEVSNKKYWGAQTERSKINFKI-GKKYSMPIEIISGLAYLKKAAAITNYELGFLSKKKKKIITKVCDEIL-EGKLNNNFPLVIWQTGSGTQTNININEVISNRAHVLSGKKLGEGiSYINPNEDVNKSQSSNDAFTTAMHIASYKiLIEKTIPGIKKLRNSLKLKSFDYKNIIKIGRTHLAP----SLGQEFSAYVSQLDKVIKELKNIINNILELAC-------------RFDLKVVNYISNLTGFEFKTAKNKL---SSHETIVITHGILKNLAISLFKISNDIRMMSS--VIGDGEIIIPSPS-------GKINPIQCEAFCMVSIKVIGNDTTISLASGSG-----VCKPVIGSNFLESAKLIGEACFSFSKNCISGINPNIPRIKKLLNQSLNLI------------------------------------------------------------------
>UniRef50_C2EBC5(1-280:294) Possible aspartate ammonia-lyase n=1 Tax=Lactobacillus ruminis ATCC 25644 RepID=C2EBC5_9LACO  E=5e-66 s/c=0.91 id=42% cov=59%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGRTQLEDAVPTTFGKEFHAYYRVLMRDHKRIEAASASLLEVPLGGTAIGTSICATQEYCDAVVPELRRLSGMPLTQAEDLSDAVQNTDCYVALSSAYKNLATDLIKITNDLRLLGSGPQAGLHELELPKVQAGSSIMPGKVNPVIPEVCAQAAFQVVGNDAAIALASSSGQLELNAFEPVMFDDLFEDASLLRGALLTLKKNCLDHLKVNEQRCAEMAAHSAGLATALSPTIGYRAAAKIAQEAVATGESIEVLLKEKINIPDSKIKELLNPQNLLQPA------------
>UniRef50_B8GH19(35-432:494) Argininosuccinate lyase n=1 Tax=Methanosphaerula palustris E1-9c RepID=ARLY_METPE  E=6e-66 s/c=0.64 id=23% cov=65%
--------------------------------------------------------------------------------------------------------------------------------------------GRSRNDEVATCLRLRLCEELLVIGDAVNGLCEVLVSLAGEHTHSVMPGFTHLQHAQPTTLAHHLLSYAQAFSRDLERLLSTYQRVNRSPLGAAAfASTGYPIDREFT-------ATMLGFSGVL-ENSMDAVSTRDFALEALADCAILMVNASRCCEELILWSSSLVRFV--QLDDAYCSTSSIMPQKKNPDTLEIMRARAGSVIGASTAALSIVKALPMSYNRDLQQLTPHLWEGIGDAGASIRILA-GALSTATFNTERMETEAGRGFSTATELADMMVREcglpfrTAHHIVGRAVRSGsltlVSLKKAATGESIdltalgLTEEKVQAALDP-------------------
>UniRef50_C1A4N7(49-437:472) Argininosuccinate lyase n=1 Tax=Gemmatimonas aurantiaca T-27 RepID=C1A4N7_GEMAT  E=2e-65 s/c=0.65 id=22% cov=56%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNDQVATASRLWTMDACQKLDAAIRELQQALLTQAETLTDAILPAYTHLQRAQPVSGTHWLLSHFWPLDRDRTRLANAARGTATLPLGSGAIaGSAFPIPRTLIK-------DTLGFA-AISPNSIDATGDRDFVAETLFACTMTAVHCSRIAEDLIIYGSSEFGFVKFG--DGFSTGSSMMPQKRNPDVFELARGSGARVLGDLVSLLGTIKGLPSGYSKDLQDDKRALFNAVDLLFL-VLPAMAGAISELRFNRDRMR-NAVSSAMMATDLADYL-----------------------------------------------------------
>UniRef50_Q1J3Z8(23-392:463) 3-carboxy-cis,cis-muconate cycloisomerase n=3 Tax=Deinococci RepID=Q1J3Z8_DEIGD  E=1e-64 s/c=0.67 id=20% cov=71%
----------------------------------------------YVRRLLTVEGALASVQGRLGIIPPESAEAIL----------HLTQTFSPDLASLRAGLLTD--------GVPVSALLAQLRPALPAAARDHLHFGATTQDIVDTAFVLAAREALRVLRRELLAVGDRLAELSQAQAQTLMPGRTHSQQALPVTFGLKAAGWLTPLTRHLERLRELEGRLYVVSFGGAA-GT-LAALGDRGLAVADALAAELDLAAPPTPWH----TQRDTVFELAAWLAGVGTSLGKLAQDVILLAQSEVGE---VREGGGGGGSSTMPQKQNPITSEVILAAASTNAGLLAAVA-RSGVQEHERGTHGWQVEWLTVPQMLGLIGAALAHTRRLLDGLEVQAARMAHNVAASHGL-------------------------------------------------------------------
>UniRef50_D1AEI5(12-423:436) Adenylosuccinate lyase n=7 Tax=Actinomycetales RepID=D1AEI5_THECD   E=3e-64 s/c=0.60 id=18% cov=67%
----------------------------------------------------------------------------------------------------------------------------------------YVHFGMTSSDLLDTALAVQLVEATDILLEKADRLVAVLRDHALEHRNTLRVGRTHGIHGEPDVWGHRVADFAFAMARSRDRLRRAREAVGVMAI-SGAVGTYSNIDP----AVERYVAERLGLKPADVSTQVVM---RDGISEWISALAIMATVCEAIALEVRHGQRTEVRELWE-PFGKGQKGSSAMPHKKNPIMSERLAGLA-RIVRAQIVPVLEGIPLWHERDISHSSTERIALPDASIALDYMLNLTIKLMSGLVVDAERMRANLESTGGLIytstvlLELVEmGMSRdDEAYPLVQKAametWETGTPFRETLRKHAAaagltLDEARLDEVCRPERFVE--------------
>UniRef50_A9NHU6(11-412:430) Adenylosuccinate lyase n=2 Tax=Mollicutes RepID=A9NHU6_ACHLI   E=4e-64 s/c=0.62 id=16% cov=65%
------------------------------------------------------------------------------------------------------------------------------------------HYGLTSTDVVDSALALILRQANQAIRSKINKLLSVLKQKAYTYKDQPTIGRTHGIHAEITSFGLKFALWYSDLKRLLSVFDAACKNIEVIKI-SGAVGNYAA----NTPQLEKTVSRLLDIASADISTQVLQ---RDRHANYISSIALLGSELEKIATEIRHLSRTEVSEVNE-YFSVDQKGSSAMPHKKNPVSSENISGLS-RVLRGYVLTAFENINLWHERDISHSSAERIILADATTLIDYMLDRITNTLSNLEVHALKLQNNIDITGGIVfsqhvlsLLIDKGLTRDHAYDLVQKiatdAMSNQKDFKTELLKSsdimKFMTPDELDKAFD--------------------
>UniRef50_Q2SR97(11-414:432) Adenylosuccinate lyase n=5 Tax=Mollicutes RepID=Q2SR97_MYCCT   E=1e-62 s/c=0.60 id=18% cov=65%
-----------------------------------------------------------------------------------------------------------------------------------------IHLGITSTDIVDTAQNYLIKQSNQIVDNELKNICDTLKELAFEHKNTLIMGRTHGMYGEPTSLGLKFALWFDEFQRHIKRFKLAKSDIQVVKI-SGSMGNYANLEP----IIEEYVANKLDMNVDSLSTQVCQRDRHIFLVEV---LANIASTLEKISTEIRLLQRSDVNELAEGFL-KNQKGSSSMPHKKNPISSENVAGLS-RYIKSIVNIVLENNNLWHERDISHSSNERIYLPDIFNLIVYILKRMNETLTNLVINQSQMlnhikqAKNIYFSQRVLTfiLLNyKNVTREKIYDLIQQitfkCFKDQSDFKDEVLKSSlteYVSIQQLEELFD--------------------
>UniRef50_B9KWU3(19-397:468) Adenylosuccinate lyase n=1 Tax=Rhodobacter sphaeroides KD131 RepID=B9KWU3_RHOSK  E=3e-62 s/c=0.64 id=20% cov=78%
------------------------------------GSRELFAPEAVYQAWLDIEAAVALVQGEMGLIPAEAAATIARTARVACLDMERVERDYVRQ-----------------RHPLMPLLGELVRK--CGEAGRYVHWGLATQNIQQTGTLFLALRGHRILLAVLDEILGHLGRLATAHADTPMAGRTHGQHAVPITLGFKFAIWIDELLQARERLRSVEARVFTVTMGG-AVG-AFSALGARGPEMQDRVAERLGMHSMSLP----SRSNRTHMCEYVQLLALCASSFHKIAEEVAQSSSVEYAELFEVHSDGV-IGSSTMPQKVNPKISMGLMANCQKLY-ALSSMMLQTAHRPFEGDACANVIYDNGTAEAMELATAIFIRAEALVAGLRADPARMEENLHSsdgrifSESIMMKLAPAMGRGEAHDLVYRAAMESR------------------------------------------
>UniRef50_C9SS79(14-446:502) Argininosuccinate lyase n=1 Tax=Verticillium albo-atrum VaMs.102 RepID=C9SS79_VERA1  E=3e-61 s/c=0.55 id=16% cov=82%
-----------------------------------------------IKEYVLTDLAHAVMLTRAGIFDAQHGASIVQALVKLHDS---------DTYAVLAPDPEVGTLGLQIEKYLEKVLGPR---------GRDIQRGRSRIDQKATNWRLINRASLTDVIRELVDLATEILATADRHTGVLMPGYTHMQHSQPTTMDHYLNAHYWAVSRSLDRLYDAYDRLNVCPLGGAAYsGTSWPINRD-------STSTYLGFDRPILNARDAGFAAIDMGAELAGVLAGTLSTISRLASDLNYWSSSEVNLVR--IDAALCGTSSMMPQKRNPMVLERIRGLAGVAVGW-AASHLGVMHTATSTDVD-QSYVHNLLPGQCIETVGAIALLREVLATAEFDVPAMRISAGQHWSTASALADRLvslrglsfrdAHESVARLVEAHERAGCrdgELRGKLIDDAFrhvLSESDVRSILDPVSFVES-------------
>UniRef50_C7M1W3(12-433:434) Adenylosuccinate lyase n=1 Tax=Acidimicrobium ferrooxidans DSM 10331 RepID=C7M1W3_ACIFD  E=8e-60 s/c=0.55 id=18% cov=66%
-----------------------------------------------------------------------------------------------------------------------------------------IHFGLTSSDVVDTALSLALVHATDRVLELVDGLADTLRVRALETRDLVCLGRTHGMAAEPTTFGAKLALFWLALERARARLVAARETISVGKL-SGAVGTYSALSP----AIERHALEALGLRPTSAT----QVIPRDRHADVVWALAALGAVLETIALEVRHLARSEVGEVAE-PFAVGQKGSSAMPHKRNPVLAERLSGMA-RLARSAVVPALEDVALWHERDISHSSVERVMLPDAFHVACYGTSLATRIVAGLTVHPEAMAQNLAATRGLVysqqvllALVRRGMARDDAYRIVQAAAArtldEDVPFLDALADDPavPLSPGELAELASAERLV---------------
>UniRef50_B5WSC5(37-445:507) Argininosuccinate lyase n=1 Tax=Burkholderia sp. H160 RepID=B5WSC5_9BURK  E=1e-58 s/c=0.56 id=21% cov=66%
------------------------------------------------------------------------------------------------------------------------------------------HTARSRNDLQSTLDRMRARQVALSLIDGNLSLRRSLIRQATRYTDCVMPGYTHLQHAQPITYGFYLSAVERGLQRDFDRLLGAFHRLNECPLGAGAMaGTTFPVDRH-------AVSALLGFS-APVAHALDAVASKDPLLELLCAALFVATTFGRLAQDFYLMST---FEFSTLTLPDSlAITSSIMPQKKNQAVLEFLKGRQSHLLGALVTGFASFRAAPYSHALDSNADSLHWLWQAVDELVETIPVMDQVISRATPNSQRMAKLAGANFSTATDLADLLvqkkglsfkeAHHITGRVVRLAIDAGlgvadippelvsRAAQEATGRDISLSREEIADALDPRAAVE--------------
>UniRef50_A8M4P0(26-466:488) Fumarate lyase n=2 Tax=Actinomycetales RepID=A8M4P0_SALAI   E=1e-58 s/c=0.52 id=18% cov=83%
-------------------------------------------------AMVEFEAALATAQARLGAVPDGTAAAIRAA--------GESGRLDLVELARLGREAANPVVGFVKHLTGLVA-------STAPEAAGHVHAGSTSQDVLDSAAMLVATRALCLVRDDLARIRTALTELARDHRGTAAVARTLTQHAVPTTFGTKAATWLTLICDAHERVNALLRQGLPVSMGGAA-GTLAAyhdhltaagvADDHPELRLATLVADELGLARPTLPWH----AARTPIADLAAVLNFVGGALGKFAADVLVLSRTEIAEVAEPAAV-GRGQSSAMPQKRNPVLS-VLVATAARQIPVYALVLGQSMVAEDERSSGAWHAEWQPLRECLRLAAGASHTAAELAQGVVVATERIRVNLSLTGSslvaerLSVALGQELGRQRAKEAVTRAVRDtemGVPaadaLRHALNEAGLVDGrsaclDSLDELLDPEGYLGAAAP----------
>UniRef50_A4WYP6(74-461:520) Argininosuccinate lyase n=5 Tax=Rhodobacteraceae RepID=A4WYP6_RHOS5   E=2e-57 s/c=0.58 id=21% cov=65%
--------------------------------------------------------------------------------------------------------------------------------------------GRSRNDIGATLDRMAVRETCLALLAEMEATRRACLEAAGRHVLTVMPGYTHLQPAQPITFGYYLANVAQGMEREHERLAAVLDRADACPLGSAALaGTSFPIDRD-------ETAALLGFA-RPAVPGLDAVASRDFVTELLWAVTSAQVLFSRVAQDLYTFTTWEFGALSFP--DRVAGTSSIMPQKKNMLPLEYFRAEAGRSIGALAGALSAVKGSNYSIGLDSVREGVADAWPAFARFRAALPLLRLILETATPDAEKLLQRCKANFSTATDLADGLvrdfgisfrdAHHVVGRAVQRVLATGGGAEDLTVEvlnaaaedeigrRFDLPEERLRRWMDP-------------------
>UniRef50_Q161F2(15-408:443) 3-carboxy-cis,cis-muconate cycloisomerase, putative n=11 Tax=Rhodobacterales RepID=Q161F2_ROSDO  E=2e-56 s/c=0.56 id=18% cov=74%
---------------------------------FPVGEtGRLFSDSAAIRAMLLVEGALAKAQGKLGIIPETSAAAIHRATLEIQIDP------------GALATSTGQNGVCVPG-----LVDAFRAEMNAPEHAQFVHWGATSQDIIDTALMLRLRQALALAESDLSELLSRLAAAAEEHATTPMAARTYGQVATPTTWGAVVAQWGMPLADALDALPHLRQSSLFVSL-SGASGTSAAL-GAQAPDLRRALAAGLGLQDPERSWHTD----RTPLLRISDWLGHVATILGSMGSSLNGLAASGIDEVAF----DRRGASSTMPQKQNPIAATGLVALSNQSC-ALRAGMTSAAQHRHQRDGTAWFSEWMLLPQIVLTTASALQIATGLAGEVQPNVAQMQAGLETGNGLI------------------------------------------------------------------
>UniRef50_Q73MK9(46-477:480) Adenylosuccinate lyase, putative n=1 Tax=Treponema denticola RepID=Q73MK9_TREDE  E=4e-56 s/c=0.51 id=17% cov=85%
--------------------------------------------------MAIVKAHLKIAEEKKGSLLPKLSGELEKTLDDIALNID-----PSEVYEEEHKTQHN-----------IRALVNVLKKKVPENTAPLVHLGATSADILDTAFSMRIRDAvIKVIIPLLKKTELLLCDIAEREAETPQVGRTHGQHAVPITFGYAVSEYVARLGKSILKMEDLVKDLR--GKFAGAVGAYNAASliVSDPMRFEKIYLDYLGLKPSEYSHQLV---EPEYMLRLLLEANIAFGIIANLADDLRNLQRTEIGEVFE-YFSATQVGSSTMPQKRNPWNSEHVKSLWKAFSPRIMSFYMD-QISEHQRDLSNSASQRFIADYLTGLALA-FNRMNSILKGLQADRENMLKNLLQGGGKvrggVMAEPAYIllaecGVSDAHEVIRKitlaAENQKISFYEALKAEEKVFAlvtERLKELnfdkpeeffANPERYRGLANVKAKALAEKYK
>UniRef50_D1A3W6(21-380:383) 3-carboxy-cis,cis-muconate cycloisomerase n=1 Tax=Thermomonospora curvata DSM 43183 RepID=D1A3W6_THECD  E=3e-55 s/c=0.61 id=21% cov=55%
------------------------------------------------RALLDAEIALARAQARLGLIPADAPAAVARAAGRITDAGRLAVQ---------ARRSGNPVVPIAAELRA---------------ATPHAHHGATSQDIADTAAMLVASRTRALILRDLDRTCAALAGLAERHRDTPMAGRTLGRPALPVTFGLKAAGWLLGCLQARRRLAQVRLPVQL----GGAAGT-MSGYGERAVELLPLYAAETGLDEPVLPWHTV----RTPVVELGAALAQTAGALGKFATDVMLLSQEEVGEVAEPAAP-GRGGSSAMPHKRNPVLSTLIRSAALQV---------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6KYN9(41-397:446) Argininosuccinate lyase n=20 Tax=Bacteroidetes RepID=ARLY_BACV8   E=3e-54 s/c=0.60 id=25% cov=41%
-----------------------------------------------------------------------------------------------------------------------------------------IHSGRSRNDQVLVDLKLFTRAELKEVAEEVEQLFHVLISQSNTYKDVLMPGYTHLQIAMPSSFGLWFGAYAESLVDDMMFLQAAFKMCNRNPLGSAAgYGSSFPLDREMT-------TRLLGFDSMDYNVVYAQMGRGKMERNVAFALASIAGTVSKMAFDACMFSSQ---NFGFVKLPDECtTGSSIMPHKKNPDVFELTRAKC------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C9Z894(26-484:484) Putative 3-carboxy-cis,cis-muconate cycloisomerase n=1 Tax=Streptomyces scabiei 87.22 RepID=C9Z894_STRSW  E=4e-54 s/c=0.47 id=18% cov=82%
---------------------------------------------AYLRALLDAEAALTRAQAALGLVPAAAGPAVTSAADAAAFDAR--------SLAERARGGGNPVIPLV----------ADLTEAVGDPYGPYVHRGATSQDIMDTATMLVAARTLDLILADLGRTESALAALAAAHRDTVMPGRTLTQHAVPTTFGLKAAGWRSLVLDARDRLAVVRASLPA--QLGGAAGTLAAFtvfrstdestdestdestdestddgnaagsgtenaaagtgaeNASTTHALVAAYAREVGLREPELPWH----TLRTPVADLAGALAFAAGALGKVAADVLVLARTEIAEVAE----GSGGGSSAMPHKANPVRSTLIAAAARRAP-QLAAALYGALAAEDERPAGAWHAEWEPLRDLLRLAGGAARDAVDLARGLRVDADVMRAHLDLTHGlivserLAAELAPVLGRARAKELltraARRVHAEGRPLGELLSEEPELSglGLDLADLVDPRRYTGSAA-----------
>UniRef50_Q8KTQ9(67-389:452) Argininosuccinate lyase n=1 Tax=Candidatus Tremblaya princeps RepID=ARLY_TREPR  E=8e-54 s/c=0.66 id=22% cov=56%
------------------------------------------------------------------------------------------------------------------------------------------HTGKSRNDQVSTTARVWLRHMAGAAICRVEELERALAARSRACLNTMMPGLTHMQVAQPVTAAHYLTAYRCMLSRDRSRLVRCTRGACVLTLGSGALaGTNHGGDRYTT-------ADMLGLHCVS-PNSLDAVSDRDFVMEYALCCAVLMVHMSRLAEDMIAWSSSIVG--FAVLGDALCTGSSIMPQKKNPDILELVRAKAAVLIGGAMGIMAVMKAQGLAYNRDNQEDKAVLLGASRAVTRSLSVMA-LAVRSLRLNKSRLRRRLESSFAIATDLA--------------------------------------------------------------
>UniRef50_Q7W582(33-445:497) Putative argininosuccinate lyase n=2 Tax=Bordetella RepID=Q7W582_BORPA  E=9e-54 s/c=0.52 id=18% cov=81%
---------------------------------------------DLFHAMSRVNLAHAVMLRDRNLIPPEAARALVALMAELFERGPSS-----VALEAGAG-----DLYPQIEAHAAALLG--------ADVAGYLQLGRSRGDVIPSAMRLKLRIKLMRLLASVLALREAILDRAVERADTIMPAYTHWQQSQIMTVGHFLGRFSAWLERDTQRLFECVSRHNLSVLGSAnGVGTSVRVDRAMT-------AAWLGHDEPTLST-GDGTNAWDYMIEPVSVAALLCSHLARLTGNFILWHTQEFGMVR--LSDAFCTASTYLPHKRNPEPLETVKVFAEQVQGALATVYLMA------RNEDWPHSLINhgfdAINGALTLSGDAADLTGAIMRDISFDPARMRELLDLSYATASEVantlvaAGGLPFREAHEIvgtaVRACMADGRAaltparVRDAARgmgiDLPPIDDAQLAACIDPGNFVQ--------------
>UniRef50_Q5LI10(41-391:447) Argininosuccinate lyase n=37 Tax=Bacteroidetes RepID=ARLY_BACFN   E=1e-53 s/c=0.61 id=25% cov=41%
-----------------------------------------------------------------------------------------------------------------------------------------IHSGRSRNDQVLLDLKLFTRTQIREVAEAVEQLFHVLIRQSERYKNVLMPGYTHLQIAMPSSFGLWFGAYAESLVDDMLFLQAAFKMCNKNPLGSAAgYGSSFPLNRTMT-------TELLGFDSLNYNVVYAQMGRGKMERNVAFALATLAGTISKLAFDACIFNSQ---NFGFVKLPDECtTGSSIMPHKKNPDVFELTRAKC------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D2R2V1(38-444:476) Adenylosuccinate lyase n=6 Tax=cellular organisms RepID=D2R2V1_9PLAN  E=6e-52 s/c=0.51 id=18% cov=64%
---------------------------------------------------------------------------------------------------------------------------------------------------------ILMREALELIARRLAVVIDALGKFATTHRELPCLGFTHLQPAQPTTVGKRATLWIYDLALDLAEIEHRIESLRARSVKGTT-GTQasflalFHGDHAKVRQLEAMVAERMGFSGSYAVT--GQTYTRKVDAQIVDTLSGVAQSAHKLASDLRLLASRKEM---EEPFEANQIGSSAMAYKRNPMRSERVCALARFVMSLQSSPAATLATQWMERTLDDSANRRLVIPQAFLGIDAVLLLLTNISSGLVVYPKTIAANLNAELPFMASENLMMAaverggdRQELHEVIRAHSqaaaldvkQEGKPntLLERLRGEPAFAGVDLAAAMNPRDFVG--------------
>UniRef50_A1B7S2(19-429:433) Fumarate lyase n=1 Tax=Paracoccus denitrificans PD1222 RepID=A1B7S2_PARDP  E=4e-51 s/c=0.50 id=17% cov=82%
-----------------------------------------------ILAMLRVEVALARAQADLGAIPAAAAEV---------IAKAAEALDPDPAELAAAVARAGITAQPVIAAL----------KSAAGEAGAFAHYGATSQDIVDTALALQLVAALDLLGGRLDRLTALLVQKAADHADLPIPARTRHQIAAPTTLGAKIAVWHGMAARNRQRLDELRPRLLLVSLHGAA-GTEAAL-AGHGPALRASMAAALGLGVPAGPWH----AARDGIAELAGWLSLVTGALGKMGLDLVQLGQSEIAEVA----AGAGGGSSTMPQKQNPVAAEALATLARLNAGDLAGMHQALVHAQ-ERDGIALGLEWNLLPGMLERSAAALRIACDLAGTLVPRPDRIAATFAADRGRMAAeaagflLAQTLPRAEALRIVAQALAQvaGGEAPTLADALARLAPgRDWAEALRPENLTGAA------------
>UniRef50_Q11FS3(39-448:510) Argininosuccinate lyase n=2 Tax=Proteobacteria RepID=Q11FS3_MESSB   E=5e-51 s/c=0.50 id=19% cov=63%
--------------------------------------------------------------------------------------------------------------------------------------------GRSRIDQGATFRRLYERQAIIAVLTELIDLEAAVIAQAANHIDTIMPGYTHLQPSQPWVFGHYLLGVAERLDIDLVRLERAYAAVNLCPLGTvGGSGSTWPLDRH-------RVASLLGFDGIVEN----ARLGRDiqYTGDIAAAASMLMATLNDLATDLQLWSMQ---EFGFVELDAGyCGTSSIFPQKKNPVALEGVRSAAAgavQWVGNVLAVSRGVGSGDLALRGA------AFLDTALQSTAQMCDLMTGVMETLIVHKDRMAERAGEGGTTASNLADTLvrelglsyraAHHAVGRFVRVCLERNLPLTGVrasefhemagLADQPRLSDEQLAVALDP-------------------
>UniRef50_A6G9Y4(29-440:441) Argininosuccinate lyase n=1 Tax=Plesiocystis pacifica SIR-1 RepID=A6G9Y4_9DELT  E=6e-51 s/c=0.50 id=22% cov=68%
---------------------------------------------------------------------------------------------------------------------------------------DKLHTGRSRNDQVATDLKLWVRSAVNRLLAGLEGLEAAIEAWNEAQGDTPMPAYTHRQVAIPVLARLWIGAALgEPLARDRRLLAVVEDEIADSPLGAGAIgGNTLPIDPWVP-------ARELRFSSPP-RNPMDAVGSRDHGLTLAFACARISQHLARFCADVVELSSDGLVTLS----GAVACGSSMMPHKRNPDLFELVRGQAALRQGELVALMTTFQGLGTGYHRDLQQDKQVLFACVDGTV-ACLEMIALGIRNLELMPERCVTALERGDAIATDLTEALvaggtafrqAYRQIGALVATQRAAGKrlvDLRAEELEAAGLPASLLDH-LDVKA--SARKRAARYVRSSE-
>UniRef50_B2KEG4(8-463:463) Adenylosuccinate lyase n=1 Tax=Elusimicrobium minutum Pei191 RepID=B2KEG4_ELUMP  E=2e-50 s/c=0.44 id=19% cov=63%
------------------------------------------------------------------------------------------------------------------------------------------------------------------LLPELKKIHKELTDLSKKYASTIILARTHGQAAVPTTFGKEFKVFEYRLRRQIKQLEKQQISCKL----GGAVGNFNAHFAAFDKVNWHSFAKkfISGFNkgrgvkifLNEVSTQID---SHDTYAELFDNVKRANTILLDFCQDMWRYISDDYI---KQRPVEGEVGSSTMPQKVNPIDFENAEGNIGLANALFGYFSSKLPVSRLQRDLSDSTVSRNFAVAFGYSVVAYSAILKG-LGKISVNTQKCAQALhEHPEVLAEGVQTILracGIQNPYEKLK-ALTRGKKIDNEVLrrfiEDLDVSKEVKDKLkkLSLEQYTGIAAKLAKGLK----
>UniRef50_B0U8T5(21-435:451) Fumarate lyase n=5 Tax=Proteobacteria RepID=B0U8T5_METS4   E=6e-49 s/c=0.47 id=20% cov=77%
-------------------------------------------------AMLRAEAALARAEAALGLVPDALAPALEA-----------IPPASLDPVALGRGTA--LSGVPVIPFV------KAVQAALPAPLEAGFHKGTTTQDIADTALVLQLRDALDLVRDDLLAILAGLSDLARRHRETPCVGRTYGQQAAPVTFGAKAAIWALGVAELAGDLPRLRGKVLTASLGG-PVGT-LAGLKEQADAVGEGFAGELALRYDPAPWH----TRRARIAQTGTWLTLVMGALAKFATDVAFLASTEVGEVAEPHVP-GRGGSSAMPHKRNPVSSTVILA-AFSAAKGQVLPLLDGMAAAQERPAGAWHAEWHALPCLFGLASGALREARALAEGLVPDPGRMRANLDLTRGllfadaAAARLAPALGAEAGHRLVEEaagAVRDGRgTLAEVLAAR---------------------------------
>UniRef50_B1LWD9(31-442:496) Fumarate lyase n=2 Tax=Bacteria RepID=B1LWD9_METRJ   E=6e-48 s/c=0.47 id=21% cov=67%
--------------------------------------------------------------------------------------------------------------------------------------------GRSRQDIIPTVLKLEQRDRLLNLAKALDETRAALLTVAEREADTIVPAYTNGVQAQPTTLGHIYLGYAAVLARDADRLRETWARLNLSPLGAAALGTSS------FPVNRERLAALLGFD-APVENSYDsgQLAPMDMGIELTGLAANLATTAGSFAQDLYAQYHQTRPWI-LLREGALTGPSSIMPQKRNPVALYSLRMKASDVVGAAQAFVIMAHNVDSGMPDYKRNQAEPPGRTLAEAAEMCRRWT-HVLDGLVVDRARAADEVAADYSTTTELADtlqreadvpfRLGHHFASELVSYGRshdlrpadlpfpEVRRIYAEAAAGSGLtpdlpLDEARFRAALSARGMIDAA------------
>UniRef50_Q23FJ3(35-488:488) Adenylosuccinate lyase family protein n=3 Tax=Oligohymenophorea RepID=Q23FJ3_TETTH  E=2e-47 s/c=0.43 id=20% cov=39%
---------------------------------------------------------------------------------------------------------------------------------------EYVHFCCTSEDINNLAYSLMLNDAkNKILLKTLEEVQTNLISMAENNSAVPMLSRTHGQVASPTTVGKELANFAYRANRQINQIKNAKFSAKLN----GAVGNFNAHIFAYPEFDWSSLSQEfiesLGLEFNPYSTQIEP---HDSIAEFYNTLSLLNTIYIGFSRDMWNYIS---IGYFKQRSKKSEVGSSTMPHKVNPI---------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D2RAU9(14-480:480) Adenylosuccinate lyase n=1 Tax=Gardnerella vaginalis 409-05 RepID=D2RAU9_GARVA  E=2e-47 s/c=0.41 id=17% cov=66%
-----------------------------------------------------------------------------------------------------------------------------------------VHFSCTSEDINNLSIARCVKQAVLNVyRPNLEAIVDYLVKNANEYRDLSMLSLTHGQPATPTTLGKELAVFAYRLRRQLRHL-DTQEYLGKLNGATGTFGAHLAAFPEVDWISVsqEFVENRMGLQWNPLTTQIE---SHDWQAELYSTVSHINHILHNLAVDVWMYISRGI----FVQVPvKGATGSSTMPHKVNPIRFENAEANLEISCSLFDTLCATLTESRWQRDLTDSTTQRNVG-SAFGYALLALNNLLGGLKSIHPNKEFMAKELDENWevlgepiqtaMRAEEIAGVPGMERPYEQVKE-LMRGHHISQSDVEE-FIKSRNFDantaarlQAMTPESYTG--------------
>UniRef50_C3RQ82(17-460:465) Adenylosuccinate lyase n=4 Tax=Bacteria RepID=C3RQ82_9MOLU   E=6e-47 s/c=0.43 id=16% cov=67%
-----------------------------------------------------------------------------------------------------------------------------------------VHIGCTSEDINNTSYACMLKYGLKDVwLPKAKEFAAIIDKWAEEHSNDAMLAHTHGQPATPTTIGKEFKVYAYRFLSSIENVEAVKIKAKFN----GATGNYSAILTAFPNEDWQVLAkkfveEYLGLTFNPLTTQIE---SHDYTCHILDGIRHFNNVLVDFDVDMWLYISMEY--FKQIPV-KGEVGSSTMPHKVNPIRFENSEANIDMSNNICIALSNKLPKSRMQRDLSDSSSQRNLGLAFGYSLQAINETMNG-LAKCVVNKDKLASDLNEKWEVLAEpiqtMLRKYGVPDAYDTLK-ALTRGKSIsKEDILKfaesLDILSDQDRQTLVDmtPASYIGLA------------
>UniRef50_D1NU88(14-473:480) Adenylosuccinate lyase n=1 Tax=Bifidobacterium gallicum DSM 20093 RepID=D1NU88_9BIFI  E=8e-47 s/c=0.41 id=18% cov=62%
-------------------------------------------------------------------------------------------------------------------------------------------------------------------LPSAKAITAHLMGKAEEFAELPMLSLTHGQPATPTTLGKELAVYVYRINRQIRHIES-QEYLGKINGATGTFGAHLAAYPDVDWVAVSRefVTNRMGLTWNPLTTQIE---SHDWQAELYGTVSHANRIMHNLCVDVWMYIS--RGVFAQVPV-KGATGSSTMPHKVNPIRFENAEANFELSCALLDTLSATLVESRWQRDLTDSTTQRNIGSALGYSLLALDNLLGG-LQSIHPDQATMQAELDANWevlgepiqtaMRACELAGLPGMERPYEKVKE-LMRGHRINQDDVQR-FIDSLQFDEqtaarlkALTPASYVGVAA-----------
>UniRef50_A0QIE8(17-373:408) 3-carboxy-cis,cis-muconate cycloisomerase n=8 Tax=Mycobacterium RepID=A0QIE8_MYCA1  E=4e-45 s/c=0.52 id=20% cov=40%
-----------------------------------------------------------------------------------------------------------------------------------------IHRGLTSQDVLDTALMLGVRALADDLIAELREQIRVLSGLTDRHRATHMVARTLTQHAAPTTFGAKAAGWLNGVLDAFDNVIALVTPVQIGGAAGTlaastelaALRTGTVDPAAVSVELARGTAAALGLAPRPP-----WHTARAPITAAADALVGCTDSWGRIAADVVTLARPEIGELGEPAT-ATRGGSSSMPHKRNPV---------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C4LH41(45-484:507) Adenylosuccinate lyase n=31 Tax=Actinomycetales RepID=C4LH41_CORK4   E=8e-44 s/c=0.41 id=17% cov=63%
---------------------------------------------------------------------------------------------------------------------------------------EHIHMGMTSRDLTENVEQLQVHRSLEHVRDRMVAVLRALADCAVRYRDQVMAGRSHNVAAQATTLGKRFASAANEILVAYERLENLISRYPLRGIKG-PMGTSqdmldlVGGDETKLEQLENSVSEYLGISRR--FDSVGQVYPRSLDLDVISALVQLGAGPSSLSMTIRLMAGNELVTEGF---KEGQVGSSAMPHKMNARSCERIGGLQIILRGYQTMAADLAGQQWNEGDVFCSVVRRVALPDAFFAFDGMVETLLTVLKEFGAFPAMIDKELERylpflatTRILMASIRAGLGRETAHEIIKEnAVATALDMRE--------------------------------------
>UniRef50_C7Q1L9(17-552:568) Fumarate lyase n=2 Tax=Actinomycetales RepID=C7Q1L9_CATAD   E=1e-42 s/c=0.33 id=17% cov=83%
--------------------------------------------PAFLQAMLDAEAALTRAQAALG--------QAPDAAAAAITAAARAENFDLRDIALRARTGGNPVIP----------LAADLTAAVPAAAAPFVHHGATSQDILDTAMMLIAARAIATVQDDLRRTADTLATLAAAHQNTPMPGRTLTQHAVPTTFGLKAAGWRTLILDSMDRLatlhlpaqlggaagtlaafevradaidhpEDFSRRSPLPGSGSTPPGTTIAHPedspgalplsasqltpsqssviaqpedlpgasplpmsaptpppgsaidypenspgrsrlsmsqltpspgstidhpedsprrsptPGSAIDLPGAFARELGLAVPELPWHVL----RTPVADLGGALAFAVGAMAKVAADVLVLSRTEVGEVAE----GAAGGSSAMPHKANPVRATLIAAAARQAP-ALAAVLFGALVAEDERPAGAWHAEWQPLRELLRLAGGAAEAAAGLVAGLRVLPDRMLDNLHRTRGlvvserLAAEVSGVLGRGPAKQLLADAADRvgslGTSLEDVLADapelKGLISRDRLRRLTDPADYLGAA------------
>UniRef50_D0REI0(24-294:319) Fumarate lyase n=1 Tax=Brucella sp. F5/99 RepID=D0REI0_9RHIZ   E=2e-42 s/c=0.65 id=21% cov=54%
-----------------------------------------------IAAMLKFEAALAGAQADLGIIPAHAAERIMSATETMEP----------DLAQLEHGTARD--------GVVVPALVRNLRKTVGEDVAAHVHFGATSQDVIDTSLMLRLARVRDILVARIEQLSERFNWLETTFGQNDLTAYTRMQPAISTTVADRVESWRAPFSDYAQRLAALQFPLQF----GGAAGT-LEKFVGKGAKLRAELAKRLGLEDRP-----QWHSQRAFIADFGHLLSLVTGSLGKFGQDIALMA-----ELRDEISLSGGGGSSAMPHKQNPVRAELL----------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1VC10(14-369:414) Fumarate lyase n=1 Tax=Frankia sp. EuI1c RepID=D1VC10_9ACTO   E=3e-42 s/c=0.49 id=21% cov=39%
-----------------------------------------------------------------------------------------------------------------------------------------VHRGLTSQDVIDTSLVLLLRDVVDRIRAQQRDQVGALAALAHTHRGTLLAGRTLTQHAVPTTFGLKAAGWLTGVLDAAE----ALDRVALPAQFGGAAGTLSAAvelarrrgHADPVAAVSGAVADATaALGLRPARP---WHTTRTTFTALGDALVAGTDAWGRIATDVATLSRPEIGELAEPAVP-GRGGSSTMPHKRNPV---------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B7AAC8(33-433:474) Argininosuccinate lyase n=1 Tax=Thermus aquaticus Y51MC23 RepID=B7AAC8_THEAQ  E=1e-37 s/c=0.40 id=22% cov=68%
-----------------------------------------------------------------------------------------------------------------------------------------VRRGLSRNDLDLTVFRAYLRDRTLALLGDLLRLRRAVLRLAARVEGVVVVLYTHHRPAQPSTLDHYLLGVESLLSRDTERLFRALSNVNRSPLGASALaGCPYPVDR-------RRLAALLGFEG-PVENTLDAVASGDYALELAAALQTLGASLSRLLTDLLFWAGRGAFLVGE----GLSQGSSLMPQKQNPVVLEHARIYAGRLMGSLEALAFLNHNTPFtDLNDHSTGVLEPLAAALEAGEAALELTRAALEEGAFVQKALMEELspeVLASEAVDLLVRKGIPLPEAYRRVRGALPGLRP------ELLGVDREELLSWVSLPAFLarrevlggvGPKAraqalsRAKRRLKEDQK
>UniRef50_A1SC84(35-447:500) Argininosuccinate lyase n=2 Tax=Nocardioides sp. JS614 RepID=A1SC84_NOCSJ  E=2e-36 s/c=0.38 id=20% cov=78%
---------------------------------------------------------------EAGVVPASAAKDLARELLQILSTP--PEEFPYDPVYGDAYNSRERELESRI-----------------GDAAGWLHTGRTRREAGRIAFRIALRRKLLDLHDAVGDLALALASAARLHAETLWADTTYLQPAQPSTFGHYLGAFAEETTRHFDRIQAAHRWANRSPAG------SGGVGGSPVLVNRKRDAATLGFD-EPGWHTRDIMWSVDGLVDAVVSATQTAATVDRLAEDLEIFASPA---FGYVRLDASlCRASVLMPQKRNPYALAVIRAGAGVLLGR-TSGLMATQRTPSAR-TDNWLHAYGEVASSVDLATRLVRLGTAVVRSLEVDEEALARAAGAHFTGAADLAEsmvlhqGLDYRSAYRVVGRAVAAAVEGERTVLDRSHLDIAAWDlfghglsDLPDVESITDPA------------
>UniRef50_D2SFW6(18-417:441) 3-carboxy-cis,cis-muconate cycloisomerase n=1 Tax=Geodermatophilus obscurus DSM 43160 RepID=D2SFW6_9ACTO  E=2e-33 s/c=0.36 id=18% cov=78%
------------------------------------------------RALLDVEAALARAAARTGVVPTTAADA-------VAAACAHPERLDLATVVARAADAGNPVPPLV------RVLQDAVGERDAVA----VHVGATSQDVLDTALLLMARNAVAAVDADLAAAADTTADLAHVHRDDVLAGRTLMQQALPTTFGLKAAGWLAGLDGARLRLAEVVASLPV--QYGGAVGT-LAASGGAGVVVRAALAEELQLTSTAVPWFTV----RLPIADLAGALGAAAGVVATVAVDVVLLAQTEVA--EVVEVGEGRGGSSAMPHKRNPVAAISARACARRAPG-LVATLLSAMEQEHERAAGAWHSEWPTLTELLSTVGSAASWLAESLRGLRPDPPRMaataaaAAEGPLAGALAEALAPTLGKgaahDAAAAAVREARDGGRPLAEVVAAR---------------------------------
>UniRef50_UPI0000510540(24-157:160) aspartate ammonia-lyase n=1 Tax=Brevibacterium linens BL2 RepID=UPI0000510540  E=2e-30 s/c=1.01 id=52% cov=28%
VSTPTRTETDSIGSLEIPAAAYWGVHTARAMENFPIARRPVSVYPDFVRAFACVKQAAARANLEIGALDEQRANLIDAACEEI-KGGRLHDQFTVGVIQGGAGTSTNMNANEVITNRALEIGGHAKGDYSFINPN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q9HKF2(40-344:433) Argininosuccinate lyase related protein n=1 Tax=Thermoplasma acidophilum RepID=Q9HKF2_THEAC  E=7e-27 s/c=0.41 id=22% cov=31%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PGTTHFMPAMPVTAATYSNYIENSLALAIRSIDRSLADASVLPYG---YGSGYGSPNSGKLKV---MSEMLGIGPVLKNPMIASSLYQFTIMQISNSIAGLSITLSRIAMDLIEYYRDGYVSLS----DEFTTGSSLMPNKRNPDYLELLQGMAA-----------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q6L1N6(92-376:420) Argininosuccinate lyase n=1 Tax=Picrophilus torridus RepID=Q6L1N6_PICTO  E=2e-26 s/c=0.43 id=24% cov=28%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PGYTHYRQAMPMSVNTYINYIKSIFYHHFNNLDSFLMDLREMPLG---YGSGYGS---FSPVDFNQVSNLLNMEKNIKNPVYSSLRYIKNIENIVYLISSLAVDISRICQDIIIYSENDIITI----PPEYTTGSSLMPNKINP----------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q8TS07(13-473:484) Fumarate hydratase class II n=89 Tax=cellular organisms RepID=FUMC_METAC  E=1e-124 s/c=0.97 id=38% cov=96%
-----RKESDSLGEVEVPADHYWGAQTQRSLIHFSIGDDYMPK--EVYHAYGYVKKAAALVNEAAGIIPPWKAELIARVADEVIA-GKLDSEFPLYVWQTGSGTQSNMNVNEVISNRAIQLVGGSLGSKHPVHPNDDVNMSQSSNDTFPTAMHIAtVLEFSNRLIPAVTVLEESIWAKAREWVDIVKIGRTHLQDATPLTVGQEWSGYATQLDDALAFVKHSLRGLYRLAIGGTAVGTGINTPPDFGEKVADEIARLTGHPFVTAPNKFAAQGSLDAMVTSSAALRTLAVALMKIANDLQWLGSGPRSGLHELILPSDEPGSSIMPGKVNPTQEEAMLMVCIQVIGEDNAVAFAGSQGNFELNAMCPIIINNVLHSARTLGDACVKFREYGINGIMLDRSRIDKFVGTSLMLVTALSPVIGYDKASAIVQRALDENTTLREAAVKGGFISAEDFDRIVDPKKMVG--------------
>UniRef50_C4QFA0(6-491:495) Fumarate hydratase n=1 Tax=Schistosoma mansoni RepID=C4QFA0_SCHMA   E=1e-111 s/c=0.83 id=35% cov=97%
-SQRLRVVEDSLGKINVPLERYYGAQTARSLGNFNVCTRSDTMPLQIVYSLAMIKEVAACTNFKLGRISSKLSDAIVKACREVYH-GQHDNEFPLVIWQTGSGTQTNMNVNEVLSSRASELIDGSRSSRLTVHPNDHVNLGQSSNDIFPTAMNLSIAmETAWKVLPSLNHLINVLKIKMHEFMNVIKIGRTHMQDAVPMSVGQELSGYVSQLQQAVDSIKSQLPLICHLAVGGTAVGTGLNCSKGFDEELCVSLTQLTdrlyrtmykestpvvDLIFKPAENKFAALAGHDALLQLSGCFNTTATALMRLSNDFCLLSSGPNCGLSEFVLPANEPGSSIMPgksyhtfGKVNPTQCESLRMVCLQIMGNHFTTSMAASQGQLELNVCKPLIAANLLHTCELLTDSTRCFADKCVRDLQLNREKIQEYVDKSLMLVTVLTPHIGYDLSAKLVQHASKFKKGLRESAIELNLLCGEKFDEIVKPMEMAFP-------------
>UniRef50_B4IYT9(22-483:489) GH16362 n=2 Tax=Drosophila RepID=B4IYT9_DROGR   E=1e-110 s/c=0.87 id=32% cov=96%
---DTRLEYDDIGAVNIPLDRIFGPTTMRSVMNIPIGGMEERIPRPIIIAMGILKKAGAEVNKEFGL-DSCISGAISSAADDVISGKLYDEnHFPLTIWQTGAGNQTNVNVNEVIGNRAIEIMGGQLGSNYPVDPNLHVNMSQNPNDCFASATNITVAMQLkEKLFPSLRLIIDALEKKEILWKNVIKVGRAHLMDEVPLTLGQEFSGYKQMMINCQTRLYSSMERLYQLSLGAATLCETPNCQPDFGYQCVKEIEVITGLPFVSAPNMHEALGARDSLIEVHGELNCIAVSTMKIANDIRFLGSGPRCGLGELILPSNEPGSSIMPGKVNPTQCEALTMICAQVMGNQVAVTVGGFNGHFELNSFMPLIASNVLRSIELLSDGLQAFVANCLEGAKPNSNKIDKFLKNSLMLATALNPYIGYNKTVQLATAALQNGTTLKQEALKIG-ISEFEFESWVRPSEMLGP-------------
>UniRef50_Q7U0N6(7-463:474) Fumarate hydratase class II n=79 Tax=cellular organisms RepID=FUMC_MYCBO  E=1e-108 s/c=0.86 id=40% cov=95%
-SANYRIEHDTMGEVRVPAKALWRAQTQRAVENFPISGRGLERTQ--IRALGLLKGACAQVNSDLGLLAPEKADA-IIAAAAEIADGQHDDQFPIDVFQTGSGTSSNMNTNEVIASIAAKG-------GVTLHPNDDVNMSQSSNDTFPTATHIAATEaAVAHLIPALQQLHDALAAKALDWHTVVKSGRTHLMDAVPVTLGQEFSGYARQIEAGIERVRACLPRLGELAIGGTAVGTGLNAPDDFGVRVVAVLVAQTGLsELRTAANSFEAQAARDGLVEASGALRTIAVSLTKIANDIRWMGSGPLTGLAEIQLPDLQPGSSIMPGKVNPVLPEAVTQVAAQVIGNDAAIAWGGANGAFELNVYIPMMARNILESFKLLTNVSRLFAQRCIAGLTANVEHLRRLAESSPSIVTPLNSAIGYEEAAAVAKQALKERKTIRQTVIDRGLigdrLSIEDLDRRLDVLAM----------------
>UniRef50_B4HEE0(1-410:410) GM24753 n=6 Tax=cellular organisms RepID=B4HEE0_DROSE   E=1e-105 s/c=0.94 id=36% cov=85%
MSSNkkveTRQESDTLGPMEVPMDRYYGAQTMRCLINFRIGGEEERMPRQIIQAMGMLKKAAAETNQEFGLDPK-LSTAISNAADDVISGKLYDEgHFPLPIWQTGSGTQSNMNSNEVIGNRAIELLGGRIGTKDPVHP-------------------------------------TTIAANAA-------PG---------------VQWYAQKLTNGLQRIDAVLPRVYQLALGGTAVGTGLNTRRGFAEKCVKRIAQLSGLPFVVAPNFFEALACRDAMVEVHGALNVLAVSLMKVTNDIRFLGSGPRCGLGELFLPENEPGSSIMPGKVNPTQCEAMTMICAQVMGNHVAVSVGGANGHFELNVFKPLIASNVLRSIKLLADGCISFNCNCVKGIKPNKEKLAKIVNESLMLVTALNPHIGYDKSAQIAKAAHKNGTTLKVEALNAG-ISEKDFNEWVRPEKMLGPS------------
>UniRef50_P39461(4-438:438) Fumarate hydratase class II n=17 Tax=Thermoprotei RepID=FUMC_SULSO   E=5e-94 s/c=0.80 id=35% cov=87%
-------------------------------------------PRRIIWSMGVLKKSCAKVNADLGLLDKKIADSIIKASDDLI-DGKLDDKIVLDVFQTGSGTGLNMNVNEVIAEVASSY------SNLKVHPNDHVNFGQSSNDTVPTAIRIAAVAEVTnRLLPALQQIISSLNKKAEEYKDVIKAGRTHLRDALPVTLGQELSAYADAFQHEHEQVMNILEYVKELPIGGTATGTGLNSHPEFQERVINEINRITGLGFKPA-NRFRAMRLLTDLLLLSGALRNIAVDLYRLGQDIRLMFSGPLTGLNEIDLPTQEeiAGSSIMPGKTNPVTVEATLLISAQVVGLDHANQFASMLGEFELSMGIPLVGYNIVTQVNFISEALEKMSRLVIDGMVANVEKMKRYAESSPSLITIVSPVIGYDKATEIGKK-LNKGMSIREALRELGY-SDNEINKILDLSKLVKPGFTAK--------
>UniRef50_B8E0N3(7-427:479) Argininosuccinate lyase n=1 Tax=Dictyoglomus turgidum DSM 6724 RepID=B8E0N3_DICTD  E=6e-85 s/c=0.75 id=21% cov=65%
-----------------------------------------------------------------------------------------------------------------------------------------IHTGRSRNDQVVLDLRLYLKEEACNIAELLIDLRKVLFDLSEKFINVPMPGYTHLQQAQPVTLAHYFLAYDAMFSRDLERLEDIYKRIDVMPLGSGALaGSNIPLDREYT-------AKLLRFS-KISDNSMDAVSDRDFVLEFLFFSALVYTHLSRLAEEIILWSTK---EFSFIRLPeEYSTGSSMMPQKRNPDVAELTRGKTGKVIGNLVNMFTVVKGLPLSYNRDLQEDKPSLFSSVDELKITLKVWTGF-LSHIEFNIDGMYRFSSEDFLFATDIAEYLvlkgmpfreAHKVVGEIVRFCEENNKKFRDLSLEDWRRFSDLFDEsvfsLLTPES-----------------
>UniRef50_O42889(21-445:447) Uncharacterized protein C8E4.05c n=9 Tax=cellular organisms RepID=YBN5_SCHPO  E=1e-84 s/c=0.74 id=18% cov=81%
------------------------------------------------------EAALARAEASLGIIPKYAGEEIQRVCK--------VENIDFSKLEEETINIGYPVLGVV----------HQLANLCSGDSGKYCHWGATTQDVTDSATVRQMIDSFKIIKGYLEKAIELATVLVIKHRETTMAGRSNLQQAVPITFGFKMARFVATLRRHHQRLCELLPRVSVLEFGG-ACGT-LASLENKGLMVQQKLAEELGL----LQPEIAWHTERDRIAEAGCFLGMLTGTLAKFATDIKLLMQTEVAEVFE-PFKANRGSSSTMPQKRNPISCVYITASTSFV-RQGVAALLDAMVEDHERATGAWEIEWIVLPDVFVHTVGTLKQTVFLLEGLEVHPSRMNENLSITNGLivseavMMALAPKLGRDEAHDLVYRlchlSIQENKPLVELLLAErqvtNYLSKEEVTSLLNPENYLGSTFE----------
>UniRef50_B3QN90(7-426:463) Argininosuccinate lyase n=3 Tax=Chlorobiaceae RepID=ARLY_CHLP8   E=9e-84 s/c=0.75 id=22% cov=69%
--------------------------------------------------------AHATMLGEEGIISAGESEQIVEGLKAVEKEIESGELVPVWEDE---------DIHTVIENRLKELIGPAAGK---------LHSGRSRNDQVATDTRLYLRRNIDRLVGLLEAMQSTLLDKAERYKSTIMFGYTHLQRAQPMSAGHYYMAWHSMFGRDAERLADLRKRANISPLGAAAfAGSTLPLNP-------ARSAELLEFDGVFA-NSIDAVSDRDLVIEFVSACSMIMMHLSRFSEDVILWTSAEFNYLS--ISDAFATGSSIMPQKKNADIAELVRGKTGRVYGNLMNLLTIMKGLPLSYNRDMQEDKPPLFDTAETTASSLSVF-RRMIEKTWLNEERLAKLTAEDLSLAT-----------------------------------------------------------------
>UniRef50_B7IJ66(21-439:451) Adenylosuccinate lyase n=4 Tax=Bacillus cereus group RepID=B7IJ66_BACC2  E=2e-83 s/c=0.74 id=17% cov=67%
----------------------------------------------------------------------------------------------------------------------------------------YIHWGATTQDIIDTGLTLQIKGAHELIYNQTQEILKICLRLSQQYKSTVMPGRTLGQHALPITFGYKISIWSDELGRHLERLQQGADRYLVGQLGG-AVGT-LASLGAQGLAVRKEYVKNLNL----IEPLVSWHTSRDRFAEFSMILNMIGATTAKVAEEIISLQGTEIREVEEGYH-SGKVGSSTMPHKRNPMTCSYIVGLTKIVNRK-STLAIDSMIQKHERDVTFWQSEWSYISEICITLSGALEQLKNVLTNLIVNEEQMKKNLFLTKGLivsenvMLELGKIIGRTTAHDLLYEltmrAFEEDKDLKDILLEDneikKYFSDEEINSLTNPESYTG--------------
>UniRef50_C9KQG3(13-418:430) Adenylosuccinate lyase n=1 Tax=Mitsuokella multacida DSM 20544 RepID=C9KQG3_9FIRM  E=2e-82 s/c=0.76 id=19% cov=79%
-----------------------------------------------------VEMAACDAMAELGEIPKEAAKNIRAKAK-----------FDVNRIHEIESVTHH----DIIAFLTNVA-------ENVGDDSKYIHKGLTSSDVKDTAYCMMMRDACTIILDDLKKFREVLRRRAKEFKHTPCIGRTHGIHAEPMTFGLKLLLWSAEIERDIERMEHAKKIVSVCKL-SGAVGTYSNIDP----KIEQMVGKKLGLTPVRLATQVIQ---RDRHAEFVTSIAICSSTLEKIATEVRNLQRTDIRE-AEEYFSPGQKGSSAMPHKRNPINCERISGMARLNRGNAVAALEDI-TLWHERDISHSSVERVILPDSSINLDYCTQKLTDIIDKLLVYPDKMLHDMNRTGGLIYSQRILLSvvdkgvlREDAYKWVQRNamkrWMEGQDFRTSVENDpditKYLTKEEIDDCFDYK------------------
>UniRef50_Q3SM68(24-436:463) Argininosuccinate lyase n=11 Tax=Bacteria RepID=ARLY_THIDA   E=5e-82 s/c=0.74 id=23% cov=62%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNDQVATDIRLYLRDAIDRILAGLKACQTSLVDLAEAHADTVMPGFTHLQVAQPVTFGHHLLAYFEMLARDAERMADCRRRVNRLPLGAAALaGTSYPIDRAY-------VARELGFEAV-CENSLDAVSDRDFAIEFAAAAALVMTHLSRLSEELILWMSPR---FGFIDLaDRFCTGSSIMPQKKNPDVPELVRGKTGRVNGHLVALLTLMKGQPLAYNKDNQEDKEPLFDTVDTLADTLAIYAD-MLRGVTVKPDAMHAAVMQGFATATDLADYLvkkglpfrdAHEVVARAVRVADESGRDLADLPLDE---------------------------------
>UniRef50_P73257(25-433:461) Argininosuccinate lyase n=20 Tax=Bacteria RepID=ARLY_SYNY3   E=8e-82 s/c=0.75 id=22% cov=62%
------------------------------------------------------------------------------------------------------------------------------------------HTARSRNDQVGTDVRLYLRAQIDDIRQRLRDFQAVLLQLAETNVETLIPGYTHLQRAQPVSLAHHLLAYFQMAQRDWQRLGEIRARTNVSPLGSGALaGTTFPIDRHYS-------AELLGFAGVYA-NSLDGVSDRDFAIEFLNAASLIMVHLSRLSEEMILWASQ---EFSFISLTDSCaTGSSIMPQKKNPDVPELIRGKAGRVMGHLQGMLVLMKGLPLAYNKDLQEDKEALFDAVKTVQVSLEAMTILLDEGIVFRQERLAEAVAEDFSNATDVADYLaakgvpfreAYNLVGKVVKTSLAAGKLLKDLTLAE---------------------------------
>UniRef50_B5YF29(11-418:433) Adenylosuccinate lyase n=1 Tax=Dictyoglomus thermophilum H-6-12 RepID=B5YF29_DICT6  E=9e-80 s/c=0.74 id=22% cov=66%
---------------------------------------------------------------------------------------------------------------------------------------EYIHQGLTSSDVMDTAFSLQIIEALNFIEDDLIKLMEEVKKKAIKYKDLPMMGRTHGMHAEPITLGFKFLGWWAELKRDLERLKKAKENISFGKF-SGVVGTLAHLSP----KVEEEACKILGLRPEPVATQVIP---RDRHAEVIYALSMIASTCERMALEIRHLQRTEVGELEE-PFREKQKGSSAMPHKRNPVLSERICGLS-RVIRGYISSALENIPLWHERDISHSSVERVIFPDATSLTDYILNLLIGIVRDLRVNEERIRENMMMNYRIyysqnvLLALTEkGVLRDVAYVWIQEdafkAMEQKRDFMEIVLEDSrireYLSREEIERCFSPE------------------
>UniRef50_B1GYN4(27-414:442) Argininosuccinate lyase n=1 Tax=uncultured Termite group 1 bacterium phylotype Rs-D17 RepID=B1GYN4_UNCTG  E=1e-78 s/c=0.76 id=19% cov=65%
------------------------------------------------------------------------------------------------------------------------------------------HTARSRNDQVVADLRIYLKQEIGIVENLINNFQKVLVEKAGENIDVVMPGFTHLQPAQPVLAAHHLLAYAWMMQRDRERLADCYKRTDVLPLGSAALaGTSFNIDRQYT-------AKLLDFE-NISENSLDAVSDRDFAAEFVFCVSLTALHLTRFCEEMILWMNPEFGYI--TIDDKFTSGSSIMPQKRNPDCAEVIRGKSGRIFGDLIALLTIIKSLPLAYNRDLQEDKPPVFDALDN-IKMCLEVISEMTESLEFVGERALKSTEKGFIAATEIADYLAknnvpFRAAHGIVKdivlYCRKNSKTLNELSIEEyngfSKIFKKDIFKYLDAKN-----------------
>UniRef50_D0CMJ0(50-464:490) Argininosuccinate lyase n=1 Tax=Synechococcus sp. WH 8109 RepID=D0CMJ0_9SYNE  E=4e-78 s/c=0.71 id=23% cov=67%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNDQVGTDLRLWLRRRLDGLDQDLQRLQGALLTQADRHRRTMIPGYTHLQRAQPLCLAHHLLAYVEMLQRDRERLQDVRKRVNICPLGAAALaGTPVPIDRQCT-------AKELGFSAVYA-NSLDAVSDRDFCVEFSAAASLVMVHLSRLAEEVIAWASE---EFGFVRLSDRCaTGSSLMPQKKNPDVPELVRGKTGRVFGHLQGLLTMIKGLPLAYNKDFQEDKEALFDAFRTTRDCVEAMAILFEEGLDFRVERLNEAVEQDFSNATDVADYLvsrgvpfreAYQLVGAVVRRCLDQRCLLRDLDLsawkELHPAFEADLHDALAPR-----AVVAARRSE----
>UniRef50_A1TNJ5(40-435:485) Argininosuccinate lyase n=50 Tax=cellular organisms RepID=ARLY_ACIAC  E=8e-77 s/c=0.73 id=22% cov=57%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNDQVATDVRLWLRGEIDMIADLLKELQRSLVDVAEQNVEVILPGFTHLQVAQPVSFAHHMLAYVEMFARDAERMQDVRRRTNVLPLGSAALaGTTYPLDR-------ERVARTLGMEGV-CQNSLDAVSDRDFAIEFTAAASLCMVHVSRLSEELIIWMSQ---NFGFIRIaDRFTTGSSIMPQKKNPDVPELARGKTGRVVGHLMGLITLMKGQPLAYNKDNQEDKEPLFDTVDTLKDTLRIFAEMVggqrdpatgrkEGGITVNPQAMEQAAQKGYATATDLADYL-----------------------------------------------------------
>UniRef50_UPI0001BC40C5(39-431:455) argininosuccinate lyase n=1 Tax=Fusobacterium sp. D12 RepID=UPI0001BC40C5  E=2e-76 s/c=0.74 id=20% cov=66%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNDQVALDMKLFVRSELRSVIELLQNLVKSLLSLAEQHLESYMPAFTHLQKAQASTFAHYLMAYVEMFFRDIQKMKNTLELLNYCPLGAAALtGTTYPIDRDLT-------SSLLHFK-APTNNSLDSVSDRDYLLDSMHNFSLTMMHLSRFCEELILFSSQDYGYIE--ISDDFSTGSSIMPQKKNPDAAELIRGKTGRVFGHLFALFTTMKSLPLAYNKDLQEDKEAFFDSLD-TTKACLSIFTEMLLKIQVHPKRMKEACYQGYIEATDIADYLttkglpfrdAYAMVGAMVKAANEEDSIFQNWTLAKfreySSLFQEDIFQMISLETMIS--------------
>UniRef50_A7GXA8(28-425:467) Argininosuccinate lyase n=78 Tax=Bacteria RepID=ARLY_CAMC5   E=7e-76 s/c=0.72 id=21% cov=71%
-------------------------------------------------------KAHAKMLGACGILKPEEAAAIVAGLDAVLA-------------QIEEGKFEFKTADEDIHMAVEKRLSELIGS----ELGGRLHTARSRNDQVALDFRLYVLRQNEQIARQIREFIATLTSLASAHLDTLMPGYTHLQHAQPVSLAYHLLAYAFMFKRDFERFISSHERNNLCPLGSAALaGTPHPIRR-------ELVAQELNFAGIT-QNAMDSVSDRDFALEILFNISVLMTHASRLCEELILWSSQ---EFGFVTIsDAYSTGSSIMPQKKNPDVAELIRGKTGRANGNLIALLTTMKGLPLAYNKDMQEDKEGVFDSVRTATSSLAIL-NAMMKEAKFNEQNMLAATKKGHLSATDLADYLVREK-------------------------------------------------------
>UniRef50_A4SIM6(2-438:461) Argininosuccinate lyase n=122 Tax=Bacteria RepID=ARLY_AERS4   E=9e-75 s/c=0.65 id=22% cov=62%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNDQVATDLKLWCKAQGELLLGSISALQAGLVASARANQAAVLPGYTHLQRAQPVTFAHWALAYVEMLERDYSRLQDALKRLDTSPLGCGALaGTAYAIDR-------EALALDMGFGGAT-RNSLDSVSDRDHVVELMHVASLSMTHLSRFAEDLIFYNTGE-AGFVELS-DAVTSGSSLMPQKKNPDALELIRGKTGRVVGAQMGMLMSLKALPLAYNKDMQEDKEGLFDALDTWHD-CLDMAALVLIDLKVNVERTKAAAQGGYANATELADYLvakgipfreAHHIVGETVVYALEVKKPLEDLSL-----------------------------------
>UniRef50_D1B689(5-426:463) Argininosuccinate lyase n=1 Tax=Thermanaerovibrio acidaminovorans DSM 6589 RepID=D1B689_THEAS  E=2e-74 s/c=0.67 id=21% cov=60%
--------------------------------------------------------------------------------------------------------------------------------------------GRSRNDQVATAVRLHLRRRLKELKGALGGLLKVLLELSERHQEVIVPGYTHLQQAQPISLGHYWMSHFWAFLRDGDRLDLALMSISRCPLGSGALaGSTLPLDRFM-------VARELGFEG-PTQNSLDSVAQRDALLDAHYFCVSCALHWSRLCEDLIIYAS---REFGWLDLPDqFCTGSSMMPQKKNPDVLELSRGKASGVLGRFVDLACMVKGLPLTYNRDLQEDKRGLFESLSV-TGSVLEVLSALLERVEVDQTRAMECFSDGLALATDVAEYLvmrrvpfreAHEKVGRLVRWCVDQGRRL----------------------------------------
>UniRef50_C9S9U9(40-371:375) Fumarate hydratase n=1 Tax=Verticillium albo-atrum VaMs.102 RepID=C9S9U9_VERA1  E=9e-73 s/c=0.83 id=37% cov=70%
MSSSTRTETDAFGALQVPADRYWGAQTERSLENFKINQPQDRMPPPIIKAFGILKGAAATVNMRYGL-DETIGKAIQQAAAEV-AEGKLLDHFPLVVWQTGSGTQSNMNANEVISNRAIEILGGEMGSKKPVHPNDHVNRSASSNDTFPTVMHIAA--------------------------------------------------------------------VLENGVGA----SSPPSEPGATPLQVK------------------------------------------------------------LNLPENEPGSSIMPGKVNPTQCEALTMVCAQVMGNHVATTIGGMNGQFELNVYKPLVIRNLLHSVRILSDGMRSFEKNLVVGLAANEQKIASIMQESLMLVTCLNPKIGYDMASKVAKNAHKKGLTLKESAMELNALTEEEFDTLVKPELMVGPA------------
>UniRef50_B4KEY6(38-420:476) GI12353 n=3 Tax=Endopterygota RepID=B4KEY6_DROMO   E=3e-71 s/c=0.71 id=22% cov=55%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNDQVVTDMKLWLRKAIRETLGRLRQLIEAIVRQAEAHLGILMPGYTHLQRAQPVQFSHWLLSHAFALREDCQRLTELRDRSNVLPLGSGALaGNPLGIDRAW-------LAERLGFAGVTG-NSMHAVGDRDFVVDFIYCCSMVSLHLSRLAEDLIIYSTK---EFDFIKIaDTFSSGSSLMPQKRNPDSLELIRGISGLITSNLTGIMMTIKGTPSTYNKDLQFDKQYCFQAYDKLTQS-LNIAVGVVETMKVQRHQMESAL-SSDMLAT-----------------------------------------------------------------
>UniRef50_Q5WG84(16-450:457) Adenylosuccinate lyase n=4 Tax=Bacteria RepID=Q5WG84_BACSK   E=4e-71 s/c=0.62 id=18% cov=83%
--------------------------------------------------------ALAEAQAEYGLIPKKAAQEIKEAAKLENLDLEEMDRIYKEIGHG-----------------FVPFL-KVLVKACPPDSGKYVHYGITTQNIQQSSQLYILKKAHMIFMRLIGEILENLSILASDNKHTVMPGRTHGRHAIPITYGYKVSAWISELISCHQRMAEAEKRVFQV-MMGGAVGT-FSSMPEIGINVQNRVAALVGMYPMTVPSRNINT----HKLEYMSNLALLANCCHKIAEEVYSTTLEEIAEVSE-GFSKGTVGSSTMPHKINPKLAKGIIANAQKLY-SLPSIGMYSAARPYEGDSSSYMLFEGLLEESMELMTEILIRCEELTRTLTVHKERMLHNAKRNKGLdnseyvMMKLAEKLGKDQAHslmyEIAMKTAAEGQEFYDNLRENKQVranfTDKEIKHMIEPGNYTGLAAhlaekEAERAKETAEK
>UniRef50_Q7UK64(12-439:460) Argininosuccinate lyase n=5 Tax=Planctomycetaceae RepID=ARLY_RHOBA   E=4e-71 s/c=0.63 id=22% cov=64%
------------------------------------------------------------------------------------------------------------------------------------------HTARSRNDQVSTDTRMWIRQSLDEIDALLVDLQSAFLSRCENDFDIILPAYTHLQRAQPVLAPHYWLAYIEKLERDRQRIADCRKRVNQCSLGIAAVaGTTLPIDR-------QHTASALDFEGITA-NSLDTSSDRDFVVESTFVMSLIASHLSGWAEEWILWST---VEFDFIQIPqAFCTGSSIMPQKVNPDTLELTRGKSARVMGALQTLMLLIKNLPLAYNRDLQEDKPPLFDAFD-TTRAMLELAAPIVRGAELKRESIAARIEKGYLDATTLmewmiARGMpqrtAHHLVGAIVSEAMQQGVTLSDLPLETYQKLSDQIDE-----------------------
>UniRef50_A9A331(36-406:485) Argininosuccinate lyase n=3 Tax=Thaumarchaeota RepID=ARLY_NITMS   E=6e-69 s/c=0.71 id=22% cov=55%
------------------------------------------------------------------------------------------------------------------------------------------HTARSRNDQVVLDIRMKIRDDINIICNCLLDTIEALVSVAKNHQKTIMPLYTHLQQAQAGLFSHYLLAHADVLSRDFQRLYGTFERINQSPLGAGPVgGTSISIDR-------RSTAKMLGFDDV-VENSIDATSTRDFVAEYVSMVSILMTNLSKIAEDFVIWSTS---EFSFIELsDEFTSPSSVMPQKKNPDILELTRGKTSEVIGNLTAILTTVKGLASGYGRDLQQIKSSIWSTSKISISALLIF-KSMLLTLKVNEKQMKKVTESSNLIA------------------------------------------------------------------
>UniRef50_C1XI32(4-429:441) Adenylosuccinate lyase n=3 Tax=Deinococci RepID=C1XI32_MEIRU   E=1e-68 s/c=0.62 id=19% cov=55%
------------------------------------------------------------------------------------------------------------------------------------------HLGLTSTDVVDTAQNVLLDEALGLIEQELDKVLTALKHLAVRYKHLPAVGRTHGVHAEPTSFGLRFLAFYAALLRDRERLGRAREGIR-VAMISGSVGNYAHVEP----AVEAWVARKLGFQIEPASSQVVP---RDRHAELMGALAILGANLERVAVELRHLQRTEVLETQE-PFSYKQTGSSSMPHKKNPVALENISGLARLLRSNLQAEL-ENVALWHERDISHSSVERVILPDTTTLAHYMLRRLGRVLEGLVVFEENIQRNLERTRGLV------------------------------------------------------------------
>UniRef50_B3E0C7(12-419:441) Adenylosuccinate lyase n=1 Tax=Methylacidiphilum infernorum V4 RepID=B3E0C7_METI4  E=3e-68 s/c=0.64 id=18% cov=67%
----------------------------------------------------------------------------------------------------------------------------------------YLHFGLTSSDILDTTFALQLKEASELLLADIEKLIQRVEQKAVQYAFCPMMGRTHGVFAEPTTYGLKLLQMREEFKRAYGRLLAAQEEI-IHGMISGAVGTYAHLDP----RVEKIVLDKLGLKAEAVSSQVIP---RDRHAFFLNCIALVGCSIERWATEFRHLQRSEVLEVEE-PFKAGQKGSSAMPHKKNPILCERLCGLA-RLLRGYALSAMENVALWHERDISHSSVERVAFPDATLLLDYMLFLLTGIVENQKVYPNRMMDNilasrqLYASEGIMLALVkKGMSRKEAYEAVQQAamncWEKGKPLSVYAQSHPlisrLLSPKEIEALCSLESYLS--------------
>UniRef50_C7M0R6(9-417:466) Argininosuccinate lyase n=1 Tax=Acidimicrobium ferrooxidans DSM 10331 RepID=C7M0R6_ACIFD  E=3e-65 s/c=0.61 id=22% cov=48%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNDQVATDLRLWARDALAEVAGGLIGFADVLRELAESAGSAVMPGYTHLQRAQPIPVAQWLLAHAWAVERDIARVLDALVRMDVSPLGAGALaGSTLPLDPPW-------VAARLGFSRSFA-NSVDAVSDRDFVAEGIFAITMAGVHLSRLAEEIVLFTTE---EFRFIRLdDAYATGSSMLPQKKNPDIAELSRAKAGRYIGDLVTILTVLKGLPLTYNRDLQEDKQPLFDAVD-----------------------------------------------------------------------------------------------------
>UniRef50_C1F4E8(38-421:486) Argininosuccinate lyase n=1 Tax=Acidobacterium capsulatum ATCC 51196 RepID=ARLY_ACIC5  E=8e-65 s/c=0.65 id=21% cov=64%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNEQIATDLRLFVRSRAQMLQAYLGTWAEILVARAQQMGNAAMPAYTHLQRAEPVLVAHWLLAYAEMLLRDASRLEDCVRRLNYCPLGSGAVaGATLALDRGIA-------SQALNFA-APTANSMDATSDRDFVLEFLQALTGIALHASRFAEEITLYAT---AEFGFVDLPeAYSTGSSAMPQKKNPDLTELVRAKVGRINGAAQAVTLLLKGLPLAYNKDMQETQEPLF-QATIATHQMLHLLAKFTHALQFRTDHMQAACESGFLNAMAAATYLVHkgipfRKAHEIVGHAVRLGL---DKGCELAGLSLDELRS-LSPE------------------
>UniRef50_A3UHH3(63-481:503) Probable lyase n=1 Tax=Oceanicaulis alexandrii HTCC2633 RepID=A3UHH3_9RHOB  E=7e-64 s/c=0.59 id=19% cov=81%
---------------------------------------------------LRLEAALARAQAQEGVIPQSA--------ADAITAAAIPDNIPQDALDAE---------YDVVRHRMVALLNVLRRSLDEDSAN-YLHYGATTVDLYDSAAMLQMREAVLALIADLRVIELQLIELAERYKSTPMIGRTLGQHALPLTYGKSVSGYIGENRRHIDRLADLLDRIDRSIIMKGAVGSYLGLGPE-GQRVEARMAQELGL---PAPYPDDWHASRDVFAEFALVQSMMAHTWARFGQEVFLLQMTDIGAVVEER-PGGAVGSSTMPHKVNPSLSEALIQ-HGRVIPRLAEIVQDDMINFFERDNT-SRPNRAVGD-VAIATEDMLGDASRLISRLRVNEARMAETLELSEGwiltqrIVFAIQDDLGREGAehrlRDLAADASETGVSLREALESDPDLlalfAPGELDALLNPRTYLG--------------
>UniRef50_C6WMX3(14-456:464) 3-carboxy-cis,cis-muconate cycloisomerase n=18 Tax=Actinomycetales RepID=C6WMX3_ACTMD  E=1e-63 s/c=0.56 id=19% cov=75%
------------------------------------------------RAMITTEVALARAQARLGVVPEAAAET--------IAAAADPDAFDWPGLVEGVHATGNPVVAFVSQLTAIVRAADTAAPATGPSAADHVHRGSTSQDVLDTATMLLCRDALRRLRTDLLATAAALAALAGRHRDTPMAGRTLTQHAVPITFGLKAAGWLAQVLDAVERVEAVLDGGLPVSLGGAA-GTLAAYGEfadGDPLDLVEPFAAELGLAPQALPWH----SARTPIADVASVLAFASGALGRLAADVAVLSRTEIGEVAEPAEP-GRGASSAMPQKRNPVHATAILTAARQVP-ALVSVLHQCLVVEDERSAGGWHAEWQPLREALRLVLGAARNAAALTAGLRAFPDRMRENLALTGGAVvserlgARLTPVLG----------------------------------------------------------
>UniRef50_B6HHB0(9-456:483) Pc20g14240 protein n=8 Tax=Fungi/Metazoa group RepID=B6HHB0_PENCW   E=6e-61 s/c=0.53 id=21% cov=68%
----------------------------------------------------------AEAQKELGL--PISAEAIEQmKAHQVIQD----DEFAV------AAEEEKRRRHDVMAHV------HAFGLVAPAAAG-IIHWGATSCYCTDNADLILLRDGLDILIPKLAVVVDKLSQFAQKYKDLPCLGFTHGQPAQLVTVGKRACLWIQDLLMDLRNLERARDDLRFRGVKGTT-GTQasflqiFNGDHAKVESLDELVTEKAGFSSAFI--ISSQTYSRKIDVDVGNALGSFGATCERIGIDIRHLAMLKEV---EEPFEKDQIGSSAMAYKRNPMRSERLCSLGRHLQNLPKDGLDTYSAQWFERSLDDSAIRRISIPELYLTADACLILLNNVSSGFVVYPEVIKRHVNDEL---------------------------------------------------------------------
>UniRef50_A8RJS2(75-457:521) Putative uncharacterized protein n=1 Tax=Clostridium bolteae ATCC BAA-613 RepID=A8RJS2_9CLOT  E=1e-60 s/c=0.62 id=21% cov=65%
--------------------------------------------------------------------------------------------------------------------------------------------GRSRNDMTPTVMRMSIRDSMLAVYERLLALIRRLLALAEENQGRIITGYTHCMPAQPITLDHYFLAIAEALVRDMDRLLSAYQNLNRSPLGACAMaGTSFPINREYT-------AQLLGFDG-IITNTLDAVATRDYLLELAADFSTLGSTLSRFAQDLYLWSTAEFNYVSF--SDAYSCCSSIMPQKKNPLSIEHIKSKSSHLTSTYLDIAMCLKGTSYGHCRDLFECMPPFWDAVEQVT-GMLELSIGTLQDITFHYDRMEFTASMNDSILTDMADFLvqkdriPFRSAHNIIASAVRAqgdnpsskitlkqlNKSSKQHLGHDTTLTESEWASLQSPRS-----------------
>UniRef50_Q1L4A5(33-439:500) Iminodisuccinate carbon-nitrogen lyase n=1 Tax=Agrobacterium tumefaciens RepID=Q1L4A5_RHIRD  E=1e-59 s/c=0.57 id=22% cov=56%
------------------------------------------------------------------------------------------------------------------------------------------HTARSRNDLYATVMRIKVRGYSVQMSHLLLDLVEAVIAKASAEMKTVMTGYTHGQPGQPITAGHYLSGISEALLRDAARILEGYDRINLNPLGACALAtTTFPIDR-------NRTGELLGFDG-LIENSLDAVGSRDYVPELIFGFAMAATTVSRFCADLHIWYMAEFNYIG--IDDSIAGTSSIMPQKKNPSPIEHLKAKASHLYGALMTSLAAQRGAFFTHGREVGTESTSGFGEAVKQFEAVAELAGAVVNGLVFNRERLIEAVDSNFSTMTELA--------------------------------------------------------------
>UniRef50_P30566(16-464:484) Adenylosuccinate lyase n=48 Tax=cellular organisms RepID=PUR8_HUMAN   E=3e-58 s/c=0.51 id=20% cov=53%
---------------------------------------------------------------------------------------------------------------------------------------------------------IILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTT-GTQASFlqlfegDDHKVEQLDKMVTEKAGFKRAFI--ITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEM---EEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQEL---------------------------------------------------------------------
>UniRef50_Q67KR2(48-477:538) Argininosuccinate lyase n=3 Tax=cellular organisms RepID=Q67KR2_SYMTH  E=1e-56 s/c=0.52 id=24% cov=61%
--------------------------------------------------------------------------------------------------------------------------------------------ARSRNDMGVTMYRMVLRKHLLDAIEAAQLLHRVLLRFAAEEADTVMLAHTHTQQAQPTTLGHWLTAAADVLERDIARMQAAYERANRSPMGAAALSTS------GFPISRERVAELLGFDG-LVENSYDAIAGADYVSEAAAAVQLTALHTGRMVQDLLLWCTQEYGALR-VADPYVQT-SSIMPQKRNPVSLEHARTLLSYTAGRAQTVLQMLHNTPFGDIVDTEDEMQPNLWAALSTLRSVFRLLANVVGTAEVNRDLLLERARASFANVTELADLLVREAglpfrtahgvVAALVKAAEARGiRDVRDV-------------------------------------
>UniRef50_Q11FP8(27-442:499) Argininosuccinate lyase n=2 Tax=Chelativorans sp. BNC1 RepID=Q11FP8_MESSB  E=1e-55 s/c=0.53 id=18% cov=59%
-------------------------------------------------------------------------------------------------------------------------------------------LGRSRIDQNAAVARVYARNSLISVMNQLVDLQGVVLDRAREWKAVIMPGYTHLQHAQPWVLGHYLLGQHDVFQRDFQRLVGVYGRTNLGSLGGVALsGTSWPIDRRYT-------AELLGHAGIVRNSKDAGNFVMDHQPELAAMLSILMSALGRLASELYIWSSW---EFGLVELDESlCGTSSIMPQKKNPYALERIRALAGEAIGWLPGQL-GLFKTPTTSDCDRS--FSSGITPCFKATRWGLLLMSEALRTMRIDENRMRERAGAFWSTASNLADLIvrergldfrrAHHVVGALVKTAVADG-------------------------------------------
>UniRef50_D2RX70(2-453:461) Adenylosuccinate lyase n=1 Tax=Haloterrigena turkmenica DSM 5511 RepID=D2RX70_9EURY  E=5e-55 s/c=0.48 id=18% cov=90%
------TDTDALYAVS-PLDGRYSSRTA------PLS--PYASEAALMRARVRVEVEYLVALADLEATPLELDLEEREHLRGLYKHFAEEDARLIKKLETeghGEFEATNHDVKAVEYFVRHELPADS-------DASAWIHFGLTSEDVNNLAHRLLVRDAVDEvLLPELYEVRDALAEMAREHQDLPMLARTHGQPATPTTFGKEMAVYASRLARATGRIRRATDDLR--GKLGGASGTYAAHHAAYPEVDWPAFAEEfvtgLGLEFEPLTTQVNPC---DDLATLFDAFRGANDVLLDLDLDIWLYVSDRYLG---QEAVEGETGSSTMPHKVNPIDFENSEGNLSKANSDLTFLADYVTTSRLQRDLSDSTVKRNIGAAFAHCLIGYTKAAAG-LEKVVPTERVMREDLESTPEIIgEAVQTILRREgqaDAYERVK-AVTRGK---DVTIEDfrEMFDDLEVDEdvreelhALTPTDYVGVA------------
>UniRef50_Q2S0F5(14-396:437) Argininosuccinate lyase n=2 Tax=Rhodothermaceae RepID=Q2S0F5_SALRD   E=3e-54 s/c=0.56 id=22% cov=54%
------------------------------------------------------------------------------------------------------------------------------------------HTGRSRNDQVLAALRLYLRDALAAIGGRAAALADALCELATRHPDVLMPGYTHLQRAMPSTAALWTLGYAETLAGDLDALRHARRRINVSPLGSAA-GYGVPV----IDLPREAVADRLGFRAVQTHATAVQLSRGKHALAVGHACTQVGATCNRLASDLVLFAT---AEFDFVDLpPEHCTGSSIMPQKQNPDVLELARAYHHRLAAQMQSLATGPSNLPGGYHRDLQLTKAAVLRSVEMTSDVLTALAE-VVRGVTFNPERTRA---------------------------------------------------------------------------
>UniRef50_Q4J8F0(47-380:447) Argininosuccinate lyase n=3 Tax=Sulfolobaceae RepID=ARLY_SULAC   E=1e-53 s/c=0.64 id=27% cov=39%
-----------------------------------------------------------------------------------------------------------------------------------------VGLGRSRNDHVATALRLRTREYIFDIMEELYLLRKSLIEQAKKNLNTIMPSYTHFQPAQPTTLAHYFMYLEEELNTPWEALFNSLKLINRSPLGSGAiVGSNVKIDR-------KREAELLGFDDVLY-NTISSTSSRIDFINAISSLTLLMLVLSRFAEDMILLSS---MFVNIIKLPDSHvSTSSLMPQKRNSVTME------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_UPI000050F815(24-446:467) 3-carboxy-cis,cis-muconate cycloisomerase n=1 Tax=Brevibacterium linens BL2 RepID=UPI000050F815  E=4e-50 s/c=0.48 id=18% cov=83%
---------------------------------------------ALVSALGDVETAWINAQAHAGLISadarAEAVEAIAATTRSLLADSAELETLAADAESGG---------NPVIPFL--KAVRSPLGE----DASRALHKGLTSQDVMDSALGLLMARVARQTHARLDVIAELLVGLSEAHADTVCLARTLTQPALPTTFGLKIASWAAEVHE----VQSLTPRIDYVQVGGAA-GTRAAIREFAGTQTETLLREfhvqLRGPDAALTSIPVPWHTDRVRVLNWASHLTQCVTVGASIARDVLIGTRPEVGELAL----AATGGSSAMPQKLNPTSAVLLHRNGMRAPGLMATLTSTAAEAIEERSDGAWHAEWPALSELMGLAVSSLIMLQTMVEGLSVNPEAMRKNVDaaSPGIFAERLNIAFGDRLSKAEVQEIINPGgvpVAALTAALEKHPTEDEEtldLAGFFSPENYLG--------------
>UniRef50_D2KUG3(37-455:464) Adenylosuccinate lyase n=2 Tax=Borrelia RepID=D2KUG3_9SPIO   E=4e-50 s/c=0.48 id=21% cov=61%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------LKNTIKTLNNFSIKYKSLATLAYTHLQEAQLTTLGKRSCLWLQSLIFDFKELNFILSNLCFRGVKGT-VGNQSSFKELFSSNFEKvktldmRLAQKMGFNKVYAITS--QTYDRKIDSSILNFLSNLSQSTHKITNDIRFLQHLKEI---EEHFEEKQIGSSAMPYKRNPIHSERIASLSKFIMSLQTSGGFIAATQWLERTLDDSACKRLNIPQAFLATDAILTLLNRIFHTIKVNEKIIEQHVkiEMPFLLTEDIlmkATKNGsdRQILHEKirtysmqVKENIYLGKHennLIKLILNDKsfKLTPKDIDEILNPNENIG--------------
>UniRef50_Q1D262(3-423:449) Argininosuccinate lyase n=2 Tax=Cystobacterineae RepID=Q1D262_MYXXD   E=6e-49 s/c=0.47 id=21% cov=87%
---------DTLWGKGLPLDA--------AIHRFTVGNDPVVDLALAPHdALGS--AAHARMLARVGLLKDAEAKSLVTALKALHDEAR-------------AGTFVIRPEQEDGHTALEAALVERVGE-----PGKRIHLGRSRNDQVQLALRLLLREEVLTLGARAAELAGAFLDFAQAHKDVALPGYTHLRRAMPSTFGLWGMAFAEGLLEELEALRGVWARLDRCPLGAAAgFGVPLPIDREY-------VAALLGFSRVQRSPIDVQNGRGRHESAVLGWACSVAGTLEKWLWDVQLYSMDEFGFLGLP--DAYTTGSSIMPQKKNPDVVELARGRCRELRGLAHQVEAVAGGLPSSYHRDFQLLKSPTLTALG-STRELLDVLTRLVPALQVKADAAARASDDTL---------YAAHHAYALV----AQGQAFRDAYKQVGR---ELVEGTFRPDRgaltATHLGGAGNLGLPQARE
>UniRef50_A6DT96(45-401:431) Argininosuccinate lyase n=1 Tax=Lentisphaera araneosa HTCC2155 RepID=A6DT96_9BACT  E=2e-47 s/c=0.54 id=23% cov=39%
-------------------------------------------------------------------------------------------------------------------------------------------MARSRNDQVVSATRLFGKDKLIKIKHTLKSFIEELLNLASKYETTPMPGYTHTQRAMPSSIGLWASSFAEILINQKETIDAAISLNDVNVLGSAAgYGTDFPIDREF-------VTKDLGLARTQVNSLSCQLSRGQVECQTLQSLWGTMFVINRLANDMVWMTS---AEFDFLDVGKSCtTGSSIMPNKKNLDPCE------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C1D231(85-418:469) Putative argininosuccinate lyase n=1 Tax=Deinococcus deserti VCD115 RepID=C1D231_DEIDV  E=2e-47 s/c=0.57 id=21% cov=65%
----------------------------------------------------------------------------------------------------------------------------------------------SRNDLDMTIYRLSARMRLMRAISRILTLRQTILTLAEREVETIIVAYTHHQPAQPTTFAHYLTAVENNLARDTERMFGALGRLNLSPMGAVALgGTSFPINRTMT-------AELLAFD-RPIENTYDAVSASDWQVELASIITITSTTLSRVLYDLLFWASR-----GLIVLPDGLVqGSSVMPQKRNPVALEHARTKFSKAIGMTQSIILSSHNVPFGDINDPGPDMQPSLHSMWQEFREGVELMTVSLASPRLNRDLWLLEAQHGESAVTELADAMtrhsgnGFRDAHARIKRllsdLHAEERPLYTVTINDLekhgiDLSEAELRSALDPAAFI---------------
>UniRef50_A9WJB9(14-460:466) Adenylosuccinate lyase n=3 Tax=Chloroflexus RepID=A9WJB9_CHLAA   E=5e-44 s/c=0.40 id=16% cov=69%
-----------------------------------------------------------------------------------------------------------------------------------------VHFALTSEDVNNLAYALMVKEAREMvLLPALESLLERIRQLADEEAATPMLARTHGQPATPTTFGKEMNVFFMRLRRAINDMMAIKITGKLNGASGVFAAHHVALPQIDWLKFSRAFVRSLDLEPILLTTQIEP---HDTLAALCDALKRIGAILTDLSQDCWRYISD---GYLVQAARAGEVGSSTMPHKVNPIDFENAEGNLALAGALLELFSRKLPVSRLQRDLSDSTVLRNLGLAFGYCLLAYQRLLRG-LQKVAVDRARLRRDLDAHpEVLAEAIQTILrreGFAEPYELLK-SFSRGRALTAEDIArfiDSLLVSDAVRaelQALAPAAYIGLAVKLAQLRDEA--
>UniRef50_UPI0001B4D80D(36-317:402) 3-carboxy-cis,cis-muconate cycloisomerase n=1 Tax=Streptomyces lividans TK24 RepID=UPI0001B4D80D  E=1e-41 s/c=0.61 id=21% cov=55%
--------------------------------------------RAYLRALLDAEAALTRAQAALGLAPAEAADA-------VGAVAADPAAFDARSLAERARGGGNPVIPLV----------ADLTKAVGEPYGPYVHRGATSQDILDTATMLVAARTLDLLLPDLARTERALARLAAEHRDTPMPGRTLTQHAVPTVFGLKAAGWRALVLDARDRITAVRDALPA--QLGGAAGTLAAFeayGATDPTALPAAYAGELGLRAPVLPWH----TLRTPIADLAGTLAFTAGALGKIAVDVLTLSRTETG----EVAEGGGGGSSAMPHKANPV---------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C4JT38(12-444:460) Adenylosuccinate lyase n=1 Tax=Uncinocarpus reesii 1704 RepID=C4JT38_UNCRE  E=2e-40 s/c=0.39 id=17% cov=78%
----------------------------------------------------------AEAEQELGInISNEALEQLR--AHQTITDQELAD----------AAVEEKRRRHDVMAHV------HVYGQTCPA-AAPIIHLGATSCYVTDNAD--------FIVSTQLTQISLTL---------------SLGQPAQLTTVGKRMCLFITDLLMDLENFEHAKKSLLSwFRGCKGTTGTQASFlqifqgQHELVERLDQLVTEKAGF--HKAFTITSQTYTRKVDTNIINYLGEFGATCERIGGDIRRLAAMKEM---EEPFEKDQIGSSAMAYKRNPMRSERLCSLGRHLQCLTQNGLTNYAAQWFERSLDDSANRRITLPEAFLTADACLILLDNISNGLVVYEKVIASRVAaelpfmATENIIMALARHdVSRQESHEEIRvlshqaAAVVKNEggqnDLIERIKRTPFFAPilDELDGLLNPSSFTGraPQQVEKFITEEVDK
>UniRef50_A3ML08(456-856:926) Argininosuccinate lyase domain protein n=36 Tax=pseudomallei group RepID=A3ML08_BURM7  E=4e-40 s/c=0.42 id=19% cov=55%
--------------------------------------------------------------------------------------------------------------------------------------------GRSRNDINAATTKLHLRDATSRAFDALWRLRRSLVFKASANVDCAFPIYSQYQPALPGTLAHQLLAFDGALAHETHALFALFQHIDVCPLG------AGAGGGTTLPIDPEFVCRLLGFE-QPAPNSLDAVANRSGVVHFLSAMNAIGLVLSRLAQDLQIWTT---AEFALVSLPaALTGGSSMLPQKKNPFLVEFVKSRAGVPFGALASCSAALGKTPYTNSFEAGSPMNGLIAQACAAIEDAAAVAVLLIDGLEAAQARIDAHLRDTGVVAMA----------------------------------------------------------------
>UniRef50_A1TNJ1(68-477:533) Argininosuccinate lyase n=7 Tax=Proteobacteria RepID=A1TNJ1_ACIAC   E=7e-39 s/c=0.40 id=20% cov=53%
--------------------------------------------------LGEINKASAVINIDQGLLDKSLAPLVHGGISKVLADGNR---------------PGGKRPRLVITF--EPLLIEAAGPQITL-----LHAGRSSQDMLSTVRAAMLRDQMLQLAEALNQTTATMVRLADRHQATVVPNYTNGVAAQPNSYGHYLLGLASGLDRDAQRIREAYARIDRSPMGTTVLnGTSWPLDR-------QRMADYLGFS-ATVDNAYDAaqVSAVDQPVEAGAIVMAIALHAGSFIEDVMTQYAQPRPWILLQEGGGNTYVSSAMPQKRNP----------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q4UB18(10-398:407) Adenylosuccinate lyase, putative n=1 Tax=Theileria annulata RepID=Q4UB18_THEAN  E=1e-21 s/c=0.28 id=22% cov=26%
------------------------------------------------------------------------------------------------------------------------------------------------------------------VKPLMLQIISTLCKLALENARMPMLSRTHGQPAIPTTFGKEVSTFVYRLSYQYK------KCISNIGLA------MFKISSKYKLWHI-LVYRNLDLNISLIQHKLSV---------------------------MILYQNCPIV-FGEV-------GSSTMPHKINPIDLE------------------------------------------------------------------------------------------------------------------------------------------------
