Phyre 2 Results for P0AC38

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Email | l.a.kelley@imperial.ac.uk
Description | P0AC38
Date | Thu Jan 5 11:17:06 GMT 2012
Unique Job ID | 86c06610d2097c58

Summary |

Top model
Image coloured by rainbow N → C terminus
| Close Jmol

Model (left) based on template d1jswa_
Top template information
Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase
Confidence and coverage
Confidence: | 100.0% | Coverage: | 96%
458 residues ( 96% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | S | N | N | I | R | I | E | E | D | L | L | G | T | R | E | V | P | A | D | A | Y | Y | G | V | H | T | L | R | A | I | E | N | F | Y | I | S | N | N | K | I | S | D | I | P | E | F | V | R | G | M | V | M | V | K | K | A | A | A | M
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | A | N | K | E | L | Q | T | I | P | K | S | V | A | N | A | I | I | A | A | C | D | E | V | L | N | N | G | K | C | M | D | Q | F | P | V | D | V | Y | Q | G | G | A | G | T | S | V | N | M | N | T | N | E | V | L | A | N | I | G | L | E
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | L | M | G | H | Q | K | G | E | Y | Q | Y | L | N | P | N | D | H | V | N | K | C | Q | S | T | N | D | A | Y | P | T | G | F | R | I | A | V | Y | S | S | L | I | K | L | V | D | A | I | N | Q | L | R | E | G | F | E | R | K | A | V | E
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240
Sequence |  | F | Q | D | I | L | K | M | G | R | T | Q | L | Q | D | A | V | P | M | T | L | G | Q | E | F | R | A | F | S | I | L | L | K | E | E | V | K | N | I | Q | R | T | A | E | L | L | L | E | V | N | L | G | A | T | A | I | G | T | G | L | N
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300
Sequence |  | T | P | K | E | Y | S | P | L | A | V | K | K | L | A | E | V | T | G | F | P | C | V | P | A | E | D | L | I | E | A | T | S | D | C | G | A | Y | V | M | V | H | G | A | L | K | R | L | A | V | K | M | S | K | I | C | N | D | L | R | L
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360
Sequence |  | L | S | S | G | P | R | A | G | L | N | E | I | N | L | P | E | L | Q | A | G | S | S | I | M | P | A | K | V | N | P | V | V | P | E | V | V | N | Q | V | C | F | K | V | I | G | N | D | T | T | V | T | M | A | A | E | A | G | Q | L | Q
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420
Sequence |  | L | N | V | M | E | P | V | I | G | Q | A | M | F | E | S | V | H | I | L | T | N | A | C | Y | N | L | L | E | K | C | I | N | G | I | T | A | N | K | E | V | C | E | G | Y | V | Y | N | S | I | G | I | V | T | Y | L | N | P | F | I | G
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | .
Sequence |  | H | H | N | G | D | I | V | G | K | I | C | A | E | T | G | K | S | V | R | E | V | V | L | E | R | G | L | L | T | E | A | E | L | D | D | I | F | S | V | Q | N | L | M | H | P | A | Y | K | A | K | R | Y | T | D | E | S | E | Q
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| d1jswa_ |

### PDB 1jsw chain A

Region: 1 - 458
Aligned: 458
Modelled: 458
Confidence: 100.0%
Identity: 100%
Fold: L-aspartase-like
Superfamily: L-aspartase-like
Family: L-aspartase/fumarase

Phyre2
2 |
| d1j3ua_ |

### PDB 1j3u chain A

Region: 5 - 469
Aligned: 462
Modelled: 465
Confidence: 100.0%
Identity: 50%
Fold: L-aspartase-like
Superfamily: L-aspartase-like
Family: L-aspartase/fumarase

Phyre2
3 |
| d1vdka_ |

### PDB 1vdk chain A

Region: 6 - 465
Aligned: 456
Modelled: 460
Confidence: 100.0%
Identity: 42%
Fold: L-aspartase-like
Superfamily: L-aspartase-like
Family: L-aspartase/fumarase

Phyre2
4 |
| c1yfmA_ |

### PDB 1yfm chain A

Region: 5 - 463
Aligned: 448
Modelled: 459
Confidence: 100.0%
Identity: 38%
PDB header:lyase
Chain: A: PDB Molecule:fumarase;
PDBTitle: recombinant yeast fumarase

Phyre2
5 |
| d1yfma_ |

### PDB 1yfm chain A

Region: 5 - 463
Aligned: 448
Modelled: 459
Confidence: 100.0%
Identity: 38%
Fold: L-aspartase-like
Superfamily: L-aspartase-like
Family: L-aspartase/fumarase

Phyre2
6 |
| d1fuoa_ |

### PDB 1fuo chain A

Region: 5 - 462
Aligned: 455
Modelled: 458
Confidence: 100.0%
Identity: 40%
Fold: L-aspartase-like
Superfamily: L-aspartase-like
Family: L-aspartase/fumarase

Phyre2
7 |
| c3no9C_ |

### PDB 3no9 chain C

Region: 2 - 464
Aligned: 447
Modelled: 450
Confidence: 100.0%
Identity: 40%
PDB header:lyase
Chain: C: PDB Molecule:fumarate hydratase class ii;
PDBTitle: crystal structure of apo fumarate hydratase from mycobacterium2 tuberculosis

Phyre2
8 |
| c3ocfB_ |

### PDB 3ocf chain B

Region: 6 - 444
Aligned: 428
Modelled: 439
Confidence: 100.0%
Identity: 52%
PDB header:lyase
Chain: B: PDB Molecule:fumarate lyase:delta crystallin;
PDBTitle: crystal structure of fumarate lyase:delta crystallin from brucella2 melitensis in native form

Phyre2
9 |
| c3e04C_ |

### PDB 3e04 chain C

Region: 5 - 418
Aligned: 412
Modelled: 414
Confidence: 100.0%
Identity: 40%
PDB header:lyase
Chain: C: PDB Molecule:fumarate hydratase;
PDBTitle: crystal structure of human fumarate hydratase

Phyre2
10 |
| d1jswc_ |

### PDB 1jsw chain C

Region: 5 - 417
Aligned: 413
Modelled: 413
Confidence: 100.0%
Identity: 100%
Fold: L-aspartase-like
Superfamily: L-aspartase-like
Family: L-aspartase/fumarase

Phyre2
11 |
| c3gtdB_ |

### PDB 3gtd chain B

Region: 4 - 409
Aligned: 399
Modelled: 406
Confidence: 100.0%
Identity: 37%
PDB header:lyase
Chain: B: PDB Molecule:fumarate hydratase class ii;
PDBTitle: 2.4 angstrom crystal structure of fumarate hydratase from rickettsia2 prowazekii

Phyre2
12 |
| c3r6yG_ |

### PDB 3r6y chain G

Region: 5 - 398
Aligned: 381
Modelled: 394
Confidence: 100.0%
Identity: 52%
PDB header:lyase
Chain: G: PDB Molecule:aspartase;
PDBTitle: crystal structure of chymotrypsin-treated aspartase from bacillus sp.2 ym55-1

Phyre2
13 |
| c2pfmA_ |

### PDB 2pfm chain A

Region: 22 - 473
Aligned: 411
Modelled: 443
Confidence: 100.0%
Identity: 19%
PDB header:lyase
Chain: A: PDB Molecule:adenylosuccinate lyase;
PDBTitle: crystal structure of adenylosuccinate lyase (purb) from bacillus2 anthracis

Phyre2
14 |
| d1re5a_ |

### PDB 1re5 chain A

Region: 20 - 478
Aligned: 416
Modelled: 445
Confidence: 100.0%
Identity: 21%
Fold: L-aspartase-like
Superfamily: L-aspartase-like
Family: L-aspartase/fumarase

Phyre2
15 |
| d1c3ca_ |

### PDB 1c3c chain A

Region: 22 - 475
Aligned: 407
Modelled: 442
Confidence: 100.0%
Identity: 19%
Fold: L-aspartase-like
Superfamily: L-aspartase-like
Family: L-aspartase/fumarase

Phyre2
16 |
| d1q5na_ |

### PDB 1q5n chain A

Region: 22 - 476
Aligned: 411
Modelled: 441
Confidence: 100.0%
Identity: 18%
Fold: L-aspartase-like
Superfamily: L-aspartase-like
Family: L-aspartase/fumarase

Phyre2
17 |
| d1tj7a_ |

### PDB 1tj7 chain A

Region: 22 - 478
Aligned: 426
Modelled: 454
Confidence: 100.0%
Identity: 19%
Fold: L-aspartase-like
Superfamily: L-aspartase-like
Family: L-aspartase/fumarase

Phyre2
18 |
| c2e9fC_ |

### PDB 2e9f chain C

Region: 31 - 478
Aligned: 416
Modelled: 433
Confidence: 100.0%
Identity: 21%
PDB header:lyase
Chain: C: PDB Molecule:argininosuccinate lyase;
PDBTitle: crystal structure of t.th.hb8 argininosuccinate lyase complexed with2 l-arginine

Phyre2
19 |
| d1i0aa_ |

### PDB 1i0a chain A

Region: 22 - 478
Aligned: 424
Modelled: 448
Confidence: 100.0%
Identity: 18%
Fold: L-aspartase-like
Superfamily: L-aspartase-like
Family: L-aspartase/fumarase

Phyre2
20 |
| d1hy0a_ |

### PDB 1hy0 chain A

Region: 31 - 478
Aligned: 415
Modelled: 424
Confidence: 100.0%
Identity: 19%
Fold: L-aspartase-like
Superfamily: L-aspartase-like
Family: L-aspartase/fumarase

Phyre2
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Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | d1jswa_ |
|  | 100.0 | 100 | Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase
2 | d1j3ua_ |
|  | 100.0 | 50 | Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase
3 | d1vdka_ |
|  | 100.0 | 42 | Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase
4 | c1yfmA_ |
|  | 100.0 | 38 | PDB header:lyase Chain: A: PDB Molecule:fumarase; PDBTitle: recombinant yeast fumarase
5 | d1yfma_ |
|  | 100.0 | 38 | Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase
6 | d1fuoa_ |
|  | 100.0 | 40 | Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase
7 | c3no9C_ |
|  | 100.0 | 40 | PDB header:lyase Chain: C: PDB Molecule:fumarate hydratase class ii; PDBTitle: crystal structure of apo fumarate hydratase from mycobacterium2 tuberculosis
8 | c3ocfB_ |
|  | 100.0 | 52 | PDB header:lyase Chain: B: PDB Molecule:fumarate lyase:delta crystallin; PDBTitle: crystal structure of fumarate lyase:delta crystallin from brucella2 melitensis in native form
9 | c3e04C_ |
|  | 100.0 | 40 | PDB header:lyase Chain: C: PDB Molecule:fumarate hydratase; PDBTitle: crystal structure of human fumarate hydratase
10 | d1jswc_ |
|  | 100.0 | 100 | Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase
11 | c3gtdB_ |
|  | 100.0 | 37 | PDB header:lyase Chain: B: PDB Molecule:fumarate hydratase class ii; PDBTitle: 2.4 angstrom crystal structure of fumarate hydratase from rickettsia2 prowazekii
12 | c3r6yG_ |
|  | 100.0 | 52 | PDB header:lyase Chain: G: PDB Molecule:aspartase; PDBTitle: crystal structure of chymotrypsin-treated aspartase from bacillus sp.2 ym55-1
13 | c2pfmA_ |
|  | 100.0 | 19 | PDB header:lyase Chain: A: PDB Molecule:adenylosuccinate lyase; PDBTitle: crystal structure of adenylosuccinate lyase (purb) from bacillus2 anthracis
14 | d1re5a_ |
|  | 100.0 | 21 | Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase
15 | d1c3ca_ |
|  | 100.0 | 19 | Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase
16 | d1q5na_ |
|  | 100.0 | 18 | Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase
17 | d1tj7a_ |
|  | 100.0 | 19 | Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase
18 | c2e9fC_ |
|  | 100.0 | 21 | PDB header:lyase Chain: C: PDB Molecule:argininosuccinate lyase; PDBTitle: crystal structure of t.th.hb8 argininosuccinate lyase complexed with2 l-arginine
19 | d1i0aa_ |
|  | 100.0 | 18 | Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase
20 | d1hy0a_ |
|  | 100.0 | 19 | Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase
21 | d1k62a_ |
| not modelled | 100.0 | 18 | Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase
22 | d1tjva_ |
| not modelled | 100.0 | 19 | Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase
23 | c3c8tA_ |
| not modelled | 100.0 | 18 | PDB header:lyase Chain: A: PDB Molecule:fumarate lyase; PDBTitle: crystal structure of fumarate lyase from mesorhizobium sp. bnc1
24 | c2vd6B_ |
| not modelled | 100.0 | 16 | PDB header:lyase Chain: B: PDB Molecule:adenylosuccinate lyase; PDBTitle: human adenylosuccinate lyase in complex with its substrate2 n6-(1,2-dicarboxyethyl)-amp, and its products amp and3 fumarate.
25 | d1dofa_ |
| not modelled | 100.0 | 17 | Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase
26 | c1yisA_ |
| not modelled | 100.0 | 15 | PDB header:lyase Chain: A: PDB Molecule:adenylosuccinate lyase; PDBTitle: structural genomics of caenorhabditis elegans: adenylosuccinate lyase
27 | c3bhgA_ |
| not modelled | 100.0 | 12 | PDB header:lyase Chain: A: PDB Molecule:adenylosuccinate lyase; PDBTitle: crystal structure of adenylosuccinate lyase from legionella2 pneumophila
28 | c2ptsA_ |
| not modelled | 100.0 | 13 | PDB header:lyase Chain: A: PDB Molecule:adenylosuccinate lyase; PDBTitle: crystal structure of wild type escherichia coli adenylosuccinate lyase
29 | c2qgaC_ |
| not modelled | 100.0 | 17 | PDB header:lyase Chain: C: PDB Molecule:adenylosuccinate lyase; PDBTitle: plasmodium vivax adenylosuccinate lyase pv003765 with amp bound
30 | c2fenA_ |
| not modelled | 100.0 | 15 | PDB header:isomerase Chain: A: PDB Molecule:3-carboxy-cis,cis-muconate lactonizing enzyme; PDBTitle: 3-carboxy-cis,cis-muconate lactonizing enzyme from agrobacterium2 radiobacter s2
31 | d1f1oa_ |
| not modelled | 100.0 | 15 | Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase
32 | c2xgvA_ |
| not modelled | 31.8 | 13 | PDB header:viral protein Chain: A: PDB Molecule:psiv capsid n-terminal domain; PDBTitle: structure of the n-terminal domain of capsid protein from2 rabbit endogenous lentivirus (relik)
33 | d2ce7a1 |
| not modelled | 27.0 | 18 | Fold:FtsH protease domain-like Superfamily:FtsH protease domain-like Family:FtsH protease domain-like
34 | d2di4a1 |
| not modelled | 26.1 | 19 | Fold:FtsH protease domain-like Superfamily:FtsH protease domain-like Family:FtsH protease domain-like
35 | c2di4B_ |
| not modelled | 21.1 | 21 | PDB header:hydrolase Chain: B: PDB Molecule:cell division protein ftsh homolog; PDBTitle: crystal structure of the ftsh protease domain
36 | c3lq9B_ |
| not modelled | 20.9 | 26 | PDB header:signaling protein Chain: B: PDB Molecule:dna-damage-inducible transcript 4 protein; PDBTitle: crystal strucure of human redd1, a hypoxia-induced regulator2 of mtor
37 | d1lbua1 |
| not modelled | 20.3 | 26 | Fold:PGBD-like Superfamily:PGBD-like Family:Peptidoglycan binding domain, PGBD
38 | d2dy1a3 |
| not modelled | 19.5 | 15 | Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:Translational machinery components
39 | c2ctoA_ |
| not modelled | 15.4 | 42 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:novel protein; PDBTitle: solution structure of the hmg box like domain from human2 hypothetical protein flj14904
40 | c3fbtB_ |
| not modelled | 14.8 | 17 | PDB header:oxidoreductase, lyase Chain: B: PDB Molecule:chorismate mutase and shikimate 5-dehydrogenase PDBTitle: crystal structure of a chorismate mutase/shikimate 5-2 dehydrogenase fusion protein from clostridium3 acetobutylicum
41 | c3bbnC_ |
| not modelled | 14.3 | 50 | PDB header:ribosome Chain: C: PDB Molecule:ribosomal protein s3; PDBTitle: homology model for the spinach chloroplast 30s subunit2 fitted to 9.4a cryo-em map of the 70s chlororibosome.
42 | c1dipA_ |
| not modelled | 13.8 | 22 | PDB header:acetylation Chain: A: PDB Molecule:delta-sleep-inducing peptide immunoreactive PDBTitle: the solution structure of porcine delta-sleep-inducing2 peptide immunoreactive peptide, nmr, 10 structures
43 | c3hzsA_ |
| not modelled | 12.5 | 11 | PDB header:transferase Chain: A: PDB Molecule:monofunctional glycosyltransferase; PDBTitle: s. aureus monofunctional glycosyltransferase (mtga)in complex with2 moenomycin
44 | d2bv3a3 |
| not modelled | 12.5 | 20 | Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:Translational machinery components
45 | d1h8ba_ |
| not modelled | 11.9 | 13 | Fold:EF Hand-like Superfamily:EF-hand Family:EF-hand modules in multidomain proteins
46 | d1nvta2 |
| not modelled | 11.7 | 13 | Fold:Aminoacid dehydrogenase-like, N-terminal domain Superfamily:Aminoacid dehydrogenase-like, N-terminal domain Family:Shikimate dehydrogenase-like
47 | c3m1eA_ |
| not modelled | 11.6 | 16 | PDB header:transcription regulator Chain: A: PDB Molecule:hth-type transcriptional regulator benm; PDBTitle: crystal structure of benm_dbd
48 | d1vi2a2 |
| not modelled | 11.4 | 14 | Fold:Aminoacid dehydrogenase-like, N-terminal domain Superfamily:Aminoacid dehydrogenase-like, N-terminal domain Family:Shikimate dehydrogenase-like
49 | d1u5ta1 |
| not modelled | 11.3 | 16 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Vacuolar sorting protein domain
50 | c2fgyA_ |
| not modelled | 11.0 | 9 | PDB header:lyase Chain: A: PDB Molecule:carboxysome shell polypeptide; PDBTitle: beta carbonic anhydrase from the carboxysomal shell of2 halothiobacillus neapolitanus (csosca)
51 | d1q3ma_ |
| not modelled | 10.5 | 23 | Fold:GLA-domain Superfamily:GLA-domain Family:GLA-domain
52 | c3bkhA_ |
| not modelled | 10.3 | 22 | PDB header:hydrolase Chain: A: PDB Molecule:lytic transglycosylase; PDBTitle: crystal structure of the bacteriophage phikz lytic2 transglycosylase, gp144
53 | c2ev9B_ |
| not modelled | 9.9 | 29 | PDB header:oxidoreductase Chain: B: PDB Molecule:shikimate 5-dehydrogenase; PDBTitle: crystal structure of shikimate 5-dehydrogenase (aroe) from thermus2 thermophilus hb8 in complex with nadp(h) and shikimate
54 | d2fug21 |
| not modelled | 9.9 | 21 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:NQO2-like
55 | d1q8ha_ |
| not modelled | 9.6 | 19 | Fold:GLA-domain Superfamily:GLA-domain Family:GLA-domain
56 | c1q8hA_ |
| not modelled | 9.6 | 19 | PDB header:metal binding protein Chain: A: PDB Molecule:osteocalcin; PDBTitle: crystal structure of porcine osteocalcin
57 | d1m9dc_ |
| not modelled | 9.2 | 15 | Fold:Retrovirus capsid protein, N-terminal core domain Superfamily:Retrovirus capsid protein, N-terminal core domain Family:Retrovirus capsid protein, N-terminal core domain
58 | c3tozA_ |
| not modelled | 9.2 | 33 | PDB header:oxidoreductase Chain: A: PDB Molecule:shikimate dehydrogenase; PDBTitle: 2.2 angstrom crystal structure of shikimate 5-dehydrogenase from2 listeria monocytogenes in complex with nad.
59 | d2b0ja1 |
| not modelled | 9.1 | 16 | Fold:6-phosphogluconate dehydrogenase C-terminal domain-like Superfamily:6-phosphogluconate dehydrogenase C-terminal domain-like Family:HMD dimerization domain-like
60 | c1nvtA_ |
| not modelled | 8.8 | 13 | PDB header:oxidoreductase Chain: A: PDB Molecule:shikimate 5'-dehydrogenase; PDBTitle: crystal structure of shikimate dehydrogenase (aroe or2 mj1084) in complex with nadp+
61 | d1npya2 |
| not modelled | 8.8 | 23 | Fold:Aminoacid dehydrogenase-like, N-terminal domain Superfamily:Aminoacid dehydrogenase-like, N-terminal domain Family:Shikimate dehydrogenase-like
62 | c2hk8B_ |
| not modelled | 8.3 | 13 | PDB header:oxidoreductase Chain: B: PDB Molecule:shikimate dehydrogenase; PDBTitle: crystal structure of shikimate dehydrogenase from aquifex2 aeolicus at 2.35 angstrom resolution
63 | c3iz5U_ |
| not modelled | 8.1 | 19 | PDB header:ribosome Chain: U: PDB Molecule:60s ribosomal protein l21 (l21e); PDBTitle: localization of the large subunit ribosomal proteins into a 5.5 a2 cryo-em map of triticum aestivum translating 80s ribosome
64 | d2qalc1 |
| not modelled | 8.0 | 38 | Fold:Alpha-lytic protease prodomain-like Superfamily:Prokaryotic type KH domain (KH-domain type II) Family:Prokaryotic type KH domain (KH-domain type II)
65 | d1p77a2 |
| not modelled | 7.5 | 14 | Fold:Aminoacid dehydrogenase-like, N-terminal domain Superfamily:Aminoacid dehydrogenase-like, N-terminal domain Family:Shikimate dehydrogenase-like
66 | c3pwzA_ |
| not modelled | 7.3 | 13 | PDB header:oxidoreductase Chain: A: PDB Molecule:shikimate dehydrogenase 3; PDBTitle: crystal structure of an ael1 enzyme from pseudomonas putida
67 | d1pbya1 |
| not modelled | 7.2 | 23 | Fold:Cytochrome c Superfamily:Cytochrome c Family:Quinohemoprotein amine dehydrogenase A chain, domains 1 and 2
68 | d1nyta2 |
| not modelled | 6.8 | 15 | Fold:Aminoacid dehydrogenase-like, N-terminal domain Superfamily:Aminoacid dehydrogenase-like, N-terminal domain Family:Shikimate dehydrogenase-like
69 | c1p74B_ |
| not modelled | 6.8 | 13 | PDB header:oxidoreductase Chain: B: PDB Molecule:shikimate 5-dehydrogenase; PDBTitle: crystal structure of shikimate dehydrogenase (aroe) from2 haemophilus influenzae
70 | c1wjvA_ |
| not modelled | 6.7 | 44 | PDB header:dna binding protein Chain: A: PDB Molecule:cell growth regulating nucleolar protein lyar; PDBTitle: solution structure of the n-terminal zinc finger domain of2 mouse cell growth regulating nucleolar protein lyar
71 | d1jmxa1 |
| not modelled | 6.6 | 10 | Fold:Cytochrome c Superfamily:Cytochrome c Family:Quinohemoprotein amine dehydrogenase A chain, domains 1 and 2
72 | c3izcU_ |
| not modelled | 6.6 | 26 | PDB header:ribosome Chain: U: PDB Molecule:60s ribosomal protein rpl21 (l21e); PDBTitle: localization of the large subunit ribosomal proteins into a 6.1 a2 cryo-em map of saccharomyces cerevisiae translating 80s ribosome
73 | c2zmeA_ |
| not modelled | 6.4 | 8 | PDB header:protein transport Chain: A: PDB Molecule:vacuolar-sorting protein snf8; PDBTitle: integrated structural and functional model of the human escrt-ii2 complex
74 | d2pxrc1 |
| not modelled | 6.3 | 15 | Fold:Retrovirus capsid protein, N-terminal core domain Superfamily:Retrovirus capsid protein, N-terminal core domain Family:Retrovirus capsid protein, N-terminal core domain
75 | c2eggA_ |
| not modelled | 6.3 | 13 | PDB header:oxidoreductase Chain: A: PDB Molecule:shikimate 5-dehydrogenase; PDBTitle: crystal structure of shikimate 5-dehydrogenase (aroe) from2 geobacillus kaustophilus
76 | c1u5tA_ |
| not modelled | 6.3 | 16 | PDB header:transport protein Chain: A: PDB Molecule:appears to be functionally related to snf7; PDBTitle: structure of the escrt-ii endosomal trafficking complex
77 | d2nr7a1 |
| not modelled | 6.1 | 26 | Fold:Lysozyme-like Superfamily:Lysozyme-like Family:NMB1012-like
78 | c1npyA_ |
| not modelled | 6.1 | 20 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical shikimate 5-dehydrogenase-like PDBTitle: structure of shikimate 5-dehydrogenase-like protein hi0607
79 | c3u62A_ |
| not modelled | 6.0 | 29 | PDB header:oxidoreductase Chain: A: PDB Molecule:shikimate dehydrogenase; PDBTitle: crystal structure of shikimate dehydrogenase from thermotoga maritima
80 | d2uubc1 |
| not modelled | 5.9 | 33 | Fold:Alpha-lytic protease prodomain-like Superfamily:Prokaryotic type KH domain (KH-domain type II) Family:Prokaryotic type KH domain (KH-domain type II)
81 | c3ff5B_ |
| not modelled | 5.9 | 35 | PDB header:protein transport Chain: B: PDB Molecule:peroxisomal biogenesis factor 14; PDBTitle: crystal structure of the conserved n-terminal domain of the2 peroxisomal matrix-protein-import receptor, pex14p
82 | c3no7A_ |
| not modelled | 5.9 | 16 | PDB header:dna binding protein Chain: A: PDB Molecule:putative plasmid related protein; PDBTitle: crystal structure of the centromere-binding protein parb from plasmid2 pcxc100
83 | c3cuqA_ |
| not modelled | 5.9 | 9 | PDB header:protein transport Chain: A: PDB Molecule:vacuolar-sorting protein snf8; PDBTitle: integrated structural and functional model of the human escrt-ii2 complex
84 | c3a8yD_ |
| not modelled | 5.8 | 14 | PDB header:hydrolase Chain: D: PDB Molecule:bag family molecular chaperone regulator 5; PDBTitle: crystal structure of the complex between the bag5 bd5 and2 hsp70 nbd
85 | c2nloA_ |
| not modelled | 5.8 | 13 | PDB header:oxidoreductase Chain: A: PDB Molecule:shikimate dehydrogenase; PDBTitle: crystal structure of the quinate dehydrogenase from corynebacterium2 glutamicum
86 | d2oqoa1 |
| not modelled | 5.8 | 13 | Fold:Lysozyme-like Superfamily:Lysozyme-like Family:PBP transglycosylase domain-like
87 | d2ga1a1 |
| not modelled | 5.7 | 23 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:Homeodomain-like Family:Alr1493-like
88 | c1b9nA_ |
| not modelled | 5.7 | 17 | PDB header:transcription Chain: A: PDB Molecule:protein (mode); PDBTitle: regulator from escherichia coli
89 | c1lbuA_ |
| not modelled | 5.6 | 23 | PDB header:hydrolase Chain: A: PDB Molecule:muramoyl-pentapeptide carboxypeptidase; PDBTitle: hydrolase metallo (zn) dd-peptidase
90 | d1g3pa2 |
| not modelled | 5.5 | 27 | Fold:N-terminal domains of the minor coat protein g3p Superfamily:N-terminal domains of the minor coat protein g3p Family:N-terminal domains of the minor coat protein g3p
91 | d2olua1 |
| not modelled | 5.2 | 11 | Fold:Lysozyme-like Superfamily:Lysozyme-like Family:PBP transglycosylase domain-like
92 | c3nojA_ |
| not modelled | 5.2 | 13 | PDB header:lyase Chain: A: PDB Molecule:4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate PDBTitle: the structure of hmg/cha aldolase from the protocatechuate degradation2 pathway of pseudomonas putida
93 | d2d28c1 |
| not modelled | 5.1 | 20 | Fold:Alpha-lytic protease prodomain-like Superfamily:EspE N-terminal domain-like Family:GSPII protein E N-terminal domain-like
94 | d1k6ya1 |
| not modelled | 5.1 | 32 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:N-terminal Zn binding domain of HIV integrase Family:N-terminal Zn binding domain of HIV integrase
95 | d1wjfa_ |
| not modelled | 5.1 | 32 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:N-terminal Zn binding domain of HIV integrase Family:N-terminal Zn binding domain of HIV integrase

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0