Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	I	R	L	Y	P	E	Q	L	R	A	Q	L	N	E	G	L	R	A	A	Y	L	L	L	G	N	D	P	L	L	L	Q	E	S	Q	D	A	V	R	Q	V	A	A	A	Q	G	F	E	E	H	H	T	F	S	I	D	P	N	T	D
Secondary structure
SS confidence
Disorder		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		W	N	A	I	F	S	L	C	Q	A	M	S	L	F	A	S	R	Q	T	L	L	L	L	L	P	E	N	G	P	N	A	A	I	N	E	Q	L	L	T	L	T	G	L	L	H	D	D	L	L	L	I	V	R	G	N	K	L	S	K	A
Secondary structure
SS confidence
Disorder										?	?	?	?	?																	?	?																										?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		Q	E	N	A	A	W	F	T	A	L	A	N	R	S	V	Q	V	T	C	Q	T	P	E	Q	A	Q	L	P	R	W	V	A	A	R	A	K	Q	L	N	L	E	L	D	D	A	A	N	Q	V	L	C	Y	C	Y	E	G	N	L	L	A
Secondary structure
SS confidence
Disorder																							?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		L	A	Q	A	L	E	R	L	S	L	L	W	P	D	G	K	L	T	L	P	R	V	E	Q	A	V	N	D	A	A	H	F	T	P	F	H	W	V	D	A	L	L	M	G	K	S	K	R	A	L	H	I	L	Q	Q	L	R	L	E	G
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		S	E	P	V	I	L	L	R	T	L	Q	R	E	L	L	L	L	V	N	L	K	R	Q	S	A	H	T	P	L	R	A	L	F	D	K	H	R	V	W	Q	N	R	R	G	M	M	G	E	A	L	N	R	L	S	Q	T	Q	L	R	Q
Secondary structure
SS confidence
Disorder																									?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.
Sequence		A	V	Q	L	L	T	R	T	E	L	T	L	K	Q	D	Y	G	Q	S	V	W	A	E	L	E	G	L	S	L	L	L	C	H	K	P	L	A	D	V	F	I	D	G
Secondary structure
SS confidence
Disorder															?			?																						?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1xxi chain F Region: 1 - 338 Aligned: 338 Modelled: 338 Confidence: 100.0% Identity: 100% PDB header:transferase Chain: F: PDB Molecule:dna polymerase iii, delta subunit; PDBTitle: adp bound e. coli clamp loader complex Phyre2 PDB 1jr3 chain D domain 2 Region: 1 - 210 Aligned: 210 Modelled: 210 Confidence: 100.0% Identity: 100% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Extended AAA-ATPase domain Phyre2 PDB 1xxh chain B Region: 7 - 339 Aligned: 315 Modelled: 333 Confidence: 100.0% Identity: 15% PDB header:transferase Chain: B: PDB Molecule:dna polymerase iii subunit gamma; PDBTitle: atpgs bound e. coli clamp loader complex Phyre2 PDB 1jql chain B Region: 1 - 140 Aligned: 140 Modelled: 140 Confidence: 100.0% Identity: 100% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Extended AAA-ATPase domain Phyre2 PDB 1jr3 chain E Region: 2 - 331 Aligned: 286 Modelled: 297 Confidence: 99.9% Identity: 17% PDB header:transferase Chain: E: PDB Molecule:dna polymerase iii, delta' subunit; PDBTitle: crystal structure of the processivity clamp loader gamma2 complex of e. coli dna polymerase iii Phyre2 PDB 1jr3 chain D domain 1 Region: 212 - 338 Aligned: 127 Modelled: 127 Confidence: 99.9% Identity: 100% Fold: post-AAA+ oligomerization domain-like Superfamily: post-AAA+ oligomerization domain-like Family: DNA polymerase III clamp loader subunits, C-terminal domain Phyre2 PDB 1iqp chain F Region: 7 - 332 Aligned: 281 Modelled: 292 Confidence: 99.7% Identity: 16% PDB header:replication Chain: F: PDB Molecule:rfcs; PDBTitle: crystal structure of the clamp loader small subunit from2 pyrococcus furiosus Phyre2 PDB 2gno chain A Region: 7 - 334 Aligned: 282 Modelled: 291 Confidence: 99.7% Identity: 16% PDB header:replication Chain: A: PDB Molecule:dna polymerase iii, gamma subunit-related protein; PDBTitle: crystal structure of a dna polymerase iii, gamma subunit-related2 protein (tm0771) from thermotoga maritima msb8 at 2.00 a resolution Phyre2 PDB 3pvs chain A Region: 9 - 339 Aligned: 298 Modelled: 324 Confidence: 99.7% Identity: 11% PDB header:recombination Chain: A: PDB Molecule:replication-associated recombination protein a; PDBTitle: structure and biochemical activities of escherichia coli mgsa Phyre2 PDB 1sxj chain D Region: 7 - 333 Aligned: 285 Modelled: 294 Confidence: 99.7% Identity: 13% PDB header:replication Chain: D: PDB Molecule:activator 1 41 kda subunit; PDBTitle: crystal structure of the eukaryotic clamp loader2 (replication factor c, rfc) bound to the dna sliding clamp3 (proliferating cell nuclear antigen, pcna) Phyre2 PDB 3u5z chain M Region: 7 - 332 Aligned: 274 Modelled: 291 Confidence: 99.7% Identity: 12% PDB header:dna binding protein/dna Chain: M: PDB Molecule:dna polymerase accessory protein 44; PDBTitle: structure of t4 bacteriophage clamp loader bound to the t4 clamp,2 primer-template dna, and atp analog Phyre2 PDB 2chv chain E Region: 7 - 332 Aligned: 281 Modelled: 292 Confidence: 99.6% Identity: 14% PDB header:dna-binding protein Chain: E: PDB Molecule:replication factor c small subunit; PDBTitle: replication factor c adpnp complex Phyre2 PDB 1sxj chain E Region: 7 - 332 Aligned: 282 Modelled: 293 Confidence: 99.6% Identity: 17% PDB header:replication Chain: E: PDB Molecule:activator 1 40 kda subunit; PDBTitle: crystal structure of the eukaryotic clamp loader2 (replication factor c, rfc) bound to the dna sliding clamp3 (proliferating cell nuclear antigen, pcna) Phyre2 PDB 1sxj chain C Region: 7 - 331 Aligned: 283 Modelled: 292 Confidence: 99.6% Identity: 13% PDB header:replication Chain: C: PDB Molecule:activator 1 40 kda subunit; PDBTitle: crystal structure of the eukaryotic clamp loader2 (replication factor c, rfc) bound to the dna sliding clamp3 (proliferating cell nuclear antigen, pcna) Phyre2 PDB 1sxj chain B Region: 7 - 333 Aligned: 281 Modelled: 294 Confidence: 99.6% Identity: 11% PDB header:replication Chain: B: PDB Molecule:activator 1 37 kda subunit; PDBTitle: crystal structure of the eukaryotic clamp loader2 (replication factor c, rfc) bound to the dna sliding clamp3 (proliferating cell nuclear antigen, pcna) Phyre2 PDB 1jr3 chain A domain 1 Region: 208 - 339 Aligned: 122 Modelled: 132 Confidence: 99.5% Identity: 17% Fold: post-AAA+ oligomerization domain-like Superfamily: post-AAA+ oligomerization domain-like Family: DNA polymerase III clamp loader subunits, C-terminal domain Phyre2 PDB 2chg chain B Region: 7 - 208 Aligned: 194 Modelled: 202 Confidence: 99.4% Identity: 9% PDB header:dna-binding protein Chain: B: PDB Molecule:replication factor c small subunit; PDBTitle: replication factor c domains 1 and 2 Phyre2 PDB 2gno chain A domain 2 Region: 7 - 191 Aligned: 176 Modelled: 179 Confidence: 99.4% Identity: 16% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Extended AAA-ATPase domain Phyre2 PDB 1sxj chain B domain 2 Region: 7 - 208 Aligned: 193 Modelled: 196 Confidence: 99.3% Identity: 10% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Extended AAA-ATPase domain Phyre2 PDB 1iqp chain A domain 2 Region: 7 - 207 Aligned: 193 Modelled: 195 Confidence: 99.3% Identity: 14% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Extended AAA-ATPase domain Phyre2 1 c1xxiF_ 2 d1jr3d2 3 c1xxhB_ 4 d1jqlb_ 5 c1jr3E_ 6 d1jr3d1 7 c1iqpF_ 8 c2gnoA_ 9 c3pvsA_ 10 c1sxjD_ 11 c3u5zM_ 12 c2chvE_ 13 c1sxjE_ 14 c1sxjC_ 15 c1sxjB_ 16 d1jr3a1 17 c2chgB_ 18 d2gnoa2 19 d1sxjb2 20 d1iqpa2 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1xxiF_ 100.0 100 PDB header:transferase Chain: F: PDB Molecule:dna polymerase iii, delta subunit; PDBTitle: adp bound e. coli clamp loader complex 2 d1jr3d2 100.0 100 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 3 c1xxhB_ 100.0 15 PDB header:transferase Chain: B: PDB Molecule:dna polymerase iii subunit gamma; PDBTitle: atpgs bound e. coli clamp loader complex 4 d1jqlb_ 100.0 100 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 5 c1jr3E_ 99.9 17 PDB header:transferase Chain: E: PDB Molecule:dna polymerase iii, delta' subunit; PDBTitle: crystal structure of the processivity clamp loader gamma2 complex of e. coli dna polymerase iii 6 d1jr3d1 99.9 100 Fold:post-AAA+ oligomerization domain-like Superfamily:post-AAA+ oligomerization domain-like Family:DNA polymerase III clamp loader subunits, C-terminal domain 7 c1iqpF_ 99.7 16 PDB header:replication Chain: F: PDB Molecule:rfcs; PDBTitle: crystal structure of the clamp loader small subunit from2 pyrococcus furiosus 8 c2gnoA_ 99.7 16 PDB header:replication Chain: A: PDB Molecule:dna polymerase iii, gamma subunit-related protein; PDBTitle: crystal structure of a dna polymerase iii, gamma subunit-related2 protein (tm0771) from thermotoga maritima msb8 at 2.00 a resolution 9 c3pvsA_ 99.7 11 PDB header:recombination Chain: A: PDB Molecule:replication-associated recombination protein a; PDBTitle: structure and biochemical activities of escherichia coli mgsa 10 c1sxjD_ 99.7 13 PDB header:replication Chain: D: PDB Molecule:activator 1 41 kda subunit; PDBTitle: crystal structure of the eukaryotic clamp loader2 (replication factor c, rfc) bound to the dna sliding clamp3 (proliferating cell nuclear antigen, pcna) 11 c3u5zM_ 99.7 12 PDB header:dna binding protein/dna Chain: M: PDB Molecule:dna polymerase accessory protein 44; PDBTitle: structure of t4 bacteriophage clamp loader bound to the t4 clamp,2 primer-template dna, and atp analog 12 c2chvE_ 99.6 14 PDB header:dna-binding protein Chain: E: PDB Molecule:replication factor c small subunit; PDBTitle: replication factor c adpnp complex 13 c1sxjE_ 99.6 17 PDB header:replication Chain: E: PDB Molecule:activator 1 40 kda subunit; PDBTitle: crystal structure of the eukaryotic clamp loader2 (replication factor c, rfc) bound to the dna sliding clamp3 (proliferating cell nuclear antigen, pcna) 14 c1sxjC_ 99.6 13 PDB header:replication Chain: C: PDB Molecule:activator 1 40 kda subunit; PDBTitle: crystal structure of the eukaryotic clamp loader2 (replication factor c, rfc) bound to the dna sliding clamp3 (proliferating cell nuclear antigen, pcna) 15 c1sxjB_ 99.6 11 PDB header:replication Chain: B: PDB Molecule:activator 1 37 kda subunit; PDBTitle: crystal structure of the eukaryotic clamp loader2 (replication factor c, rfc) bound to the dna sliding clamp3 (proliferating cell nuclear antigen, pcna) 16 d1jr3a1 99.5 17 Fold:post-AAA+ oligomerization domain-like Superfamily:post-AAA+ oligomerization domain-like Family:DNA polymerase III clamp loader subunits, C-terminal domain 17 c2chgB_ 99.4 9 PDB header:dna-binding protein Chain: B: PDB Molecule:replication factor c small subunit; PDBTitle: replication factor c domains 1 and 2 18 d2gnoa2 99.4 16 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 19 d1sxjb2 99.3 10 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 20 d1iqpa2 99.3 14 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 21 d1sxjc2 not modelled 99.3 14 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 22 d1njfa_ not modelled 99.3 14 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 23 c1sxjA_ not modelled 99.2 15 PDB header:replication Chain: A: PDB Molecule:activator 1 95 kda subunit; PDBTitle: crystal structure of the eukaryotic clamp loader2 (replication factor c, rfc) bound to the dna sliding clamp3 (proliferating cell nuclear antigen, pcna) 24 d1sxje2 not modelled 99.2 15 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 25 d1sxjd2 not modelled 99.1 11 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 26 c3bosA_ not modelled 99.0 14 PDB header:hydrolase regulator,dna binding protein Chain: A: PDB Molecule:putative dna replication factor; PDBTitle: crystal structure of a putative dna replication regulator hda2 (sama_1916) from shewanella amazonensis sb2b at 1.75 a resolution 27 d1a5ta2 not modelled 99.0 17 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 28 d1sxja2 not modelled 98.9 14 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 29 d1in4a2 not modelled 98.9 12 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 30 c3pfiB_ not modelled 98.7 13 PDB header:hydrolase Chain: B: PDB Molecule:holliday junction atp-dependent dna helicase ruvb; PDBTitle: 2.7 angstrom resolution crystal structure of a probable holliday2 junction dna helicase (ruvb) from campylobacter jejuni subsp. jejuni3 nctc 11168 in complex with adenosine-5'-diphosphate 31 c2z4rB_ not modelled 98.6 12 PDB header:dna binding protein Chain: B: PDB Molecule:chromosomal replication initiator protein dnaa; PDBTitle: crystal structure of domain iii from the thermotoga2 maritima replication initiation protein dnaa 32 c1in8A_ not modelled 98.6 12 PDB header:dna binding protein Chain: A: PDB Molecule:holliday junction dna helicase ruvb; PDBTitle: thermotoga maritima ruvb t158v 33 d1ixsb2 not modelled 98.2 13 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 34 d1l8qa2 not modelled 97.8 12 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 35 c2c9oC_ not modelled 97.6 11 PDB header:hydrolase Chain: C: PDB Molecule:ruvb-like 1; PDBTitle: 3d structure of the human ruvb-like helicase ruvbl1 36 c3te6A_ not modelled 97.6 14 PDB header:gene regulation Chain: A: PDB Molecule:regulatory protein sir3; PDBTitle: crystal structure of the s. cerevisiae sir3 aaa+ domain 37 d1ny5a2 not modelled 97.5 13 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 38 d1w5sa2 not modelled 97.5 11 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 39 d1r6bx2 not modelled 97.1 11 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 40 c1ny5A_ not modelled 97.0 11 PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator (ntrc family); PDBTitle: crystal structure of sigm54 activator (aaa+ atpase) in the inactive2 state 41 d1fnna2 not modelled 96.9 15 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 42 c3h4mC_ not modelled 96.9 13 PDB header:hydrolase Chain: C: PDB Molecule:proteasome-activating nucleotidase; PDBTitle: aaa atpase domain of the proteasome- activating nucleotidase 43 c2ce7B_ not modelled 96.8 12 PDB header:cell division protein Chain: B: PDB Molecule:cell division protein ftsh; PDBTitle: edta treated 44 d1sxjd1 not modelled 96.8 16 Fold:post-AAA+ oligomerization domain-like Superfamily:post-AAA+ oligomerization domain-like Family:DNA polymerase III clamp loader subunits, C-terminal domain 45 d1ixza_ not modelled 96.3 15 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 46 c3b9pA_ not modelled 95.8 15 PDB header:hydrolase Chain: A: PDB Molecule:cg5977-pa, isoform a; PDBTitle: spastin 47 c1ojlF_ not modelled 95.8 16 PDB header:response regulator Chain: F: PDB Molecule:transcriptional regulatory protein zrar; PDBTitle: crystal structure of a sigma54-activator suggests the2 mechanism for the conformational switch necessary for3 sigma54 binding 48 c2c99A_ not modelled 95.8 14 PDB header:transcription regulation Chain: A: PDB Molecule:psp operon transcriptional activator; PDBTitle: structural basis of the nucleotide driven conformational2 changes in the aaa domain of transcription activator pspf 49 d2ce7a2 not modelled 95.5 13 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 50 c2zamA_ not modelled 95.4 14 PDB header:protein transport Chain: A: PDB Molecule:vacuolar protein sorting-associating protein 4b; PDBTitle: crystal structure of mouse skd1/vps4b apo-form 51 c1hqcB_ not modelled 95.3 14 PDB header:hydrolase Chain: B: PDB Molecule:ruvb; PDBTitle: structure of ruvb from thermus thermophilus hb8 52 c3d8bB_ not modelled 95.1 13 PDB header:hydrolase Chain: B: PDB Molecule:fidgetin-like protein 1; PDBTitle: crystal structure of human fidgetin-like protein 1 in complex with adp 53 c2dhrC_ not modelled 95.1 15 PDB header:hydrolase Chain: C: PDB Molecule:ftsh; PDBTitle: whole cytosolic region of atp-dependent metalloprotease2 ftsh (g399l) 54 c1r6bX_ not modelled 95.0 15 PDB header:hydrolase Chain: X: PDB Molecule:clpa protein; PDBTitle: high resolution crystal structure of clpa 55 d1iqpa1 not modelled 94.8 18 Fold:post-AAA+ oligomerization domain-like Superfamily:post-AAA+ oligomerization domain-like Family:DNA polymerase III clamp loader subunits, C-terminal domain 56 c1iy2A_ not modelled 94.5 14 PDB header:hydrolase Chain: A: PDB Molecule:atp-dependent metalloprotease ftsh; PDBTitle: crystal structure of the ftsh atpase domain from thermus2 thermophilus 57 d1qvra2 not modelled 94.5 11 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 58 c2r65A_ not modelled 94.2 14 PDB header:hydrolase Chain: A: PDB Molecule:cell division protease ftsh homolog; PDBTitle: crystal structure of helicobacter pylori atp dependent protease, ftsh2 adp complex 59 c2v1uA_ not modelled 94.1 13 PDB header:replication Chain: A: PDB Molecule:cell division control protein 6 homolog; PDBTitle: structure of the aeropyrum pernix orc1 protein in complex2 with dna 60 c1qvrB_ not modelled 93.6 19 PDB header:chaperone Chain: B: PDB Molecule:clpb protein; PDBTitle: crystal structure analysis of clpb 61 d1jbka_ not modelled 93.5 12 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 62 c1xwiA_ not modelled 93.1 14 PDB header:protein transport Chain: A: PDB Molecule:skd1 protein; PDBTitle: crystal structure of vps4b 63 c2hcbC_ not modelled 92.7 14 PDB header:replication Chain: C: PDB Molecule:chromosomal replication initiator protein dnaa; PDBTitle: structure of amppcp-bound dnaa from aquifex aeolicus 64 c1fnnB_ not modelled 91.5 11 PDB header:cell cycle Chain: B: PDB Molecule:cell division control protein 6; PDBTitle: crystal structure of cdc6p from pyrobaculum aerophilum 65 c3hteC_ not modelled 91.1 17 PDB header:motor protein Chain: C: PDB Molecule:atp-dependent clp protease atp-binding subunit clpx; PDBTitle: crystal structure of nucleotide-free hexameric clpx 66 d1id3b_ not modelled 90.8 8 Fold:Histone-fold Superfamily:Histone-fold Family:Nucleosome core histones 67 c3dzdA_ not modelled 90.7 15 PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional regulator (ntrc family); PDBTitle: crystal structure of sigma54 activator ntrc4 in the inactive2 state 68 d1qvra3 not modelled 90.7 17 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 69 d1hiod_ not modelled 89.2 8 Fold:Histone-fold Superfamily:Histone-fold Family:Nucleosome core histones 70 d1sxjc1 not modelled 89.2 11 Fold:post-AAA+ oligomerization domain-like Superfamily:post-AAA+ oligomerization domain-like Family:DNA polymerase III clamp loader subunits, C-terminal domain 71 d2huec1 not modelled 88.7 8 Fold:Histone-fold Superfamily:Histone-fold Family:Nucleosome core histones 72 c2kjqA_ not modelled 88.7 11 PDB header:replication Chain: A: PDB Molecule:dnaa-related protein; PDBTitle: solution structure of protein nmb1076 from neisseria meningitidis.2 northeast structural genomics consortium target mr101b. 73 d1e32a2 not modelled 87.4 15 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 74 d1r6bx3 not modelled 87.2 16 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 75 d1lv7a_ not modelled 86.5 12 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 76 d1tafb_ not modelled 86.2 15 Fold:Histone-fold Superfamily:Histone-fold Family:TBP-associated factors, TAFs 77 d1sxjb1 not modelled 85.9 19 Fold:post-AAA+ oligomerization domain-like Superfamily:post-AAA+ oligomerization domain-like Family:DNA polymerase III clamp loader subunits, C-terminal domain 78 d1kx5b_ not modelled 85.7 8 Fold:Histone-fold Superfamily:Histone-fold Family:Nucleosome core histones 79 c2v6zM_ not modelled 85.4 22 PDB header:transferase Chain: M: PDB Molecule:dna polymerase epsilon subunit 2; PDBTitle: solution structure of amino terminal domain of human dna2 polymerase epsilon subunit b 80 c2qz4A_ not modelled 85.3 13 PDB header:hydrolase Chain: A: PDB Molecule:paraplegin; PDBTitle: human paraplegin, aaa domain in complex with adp 81 d1a5ta1 not modelled 83.6 22 Fold:post-AAA+ oligomerization domain-like Superfamily:post-AAA+ oligomerization domain-like Family:DNA polymerase III clamp loader subunits, C-terminal domain 82 d1g41a_ not modelled 81.3 18 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 83 d1r7ra3 not modelled 80.8 12 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 84 c2qbyB_ not modelled 78.9 12 PDB header:replication/dna Chain: B: PDB Molecule:cell division control protein 6 homolog 3; PDBTitle: crystal structure of a heterodimer of cdc6/orc1 initiators2 bound to origin dna (from s. solfataricus) 85 c3pxiB_ not modelled 77.8 16 PDB header:protein binding Chain: B: PDB Molecule:negative regulator of genetic competence clpc/mecb; PDBTitle: structure of meca108:clpc 86 c3pxgA_ not modelled 76.5 10 PDB header:protein binding Chain: A: PDB Molecule:negative regulator of genetic competence clpc/mecb; PDBTitle: structure of meca121 and clpc1-485 complex 87 c2qbyA_ not modelled 75.4 13 PDB header:replication/dna Chain: A: PDB Molecule:cell division control protein 6 homolog 1; PDBTitle: crystal structure of a heterodimer of cdc6/orc1 initiators2 bound to origin dna (from s. solfataricus) 88 d1htaa_ not modelled 71.5 17 Fold:Histone-fold Superfamily:Histone-fold Family:Archaeal histone 89 d1a7wa_ not modelled 69.9 19 Fold:Histone-fold Superfamily:Histone-fold Family:Archaeal histone 90 c3eihB_ not modelled 68.8 16 PDB header:protein transport Chain: B: PDB Molecule:vacuolar protein sorting-associated protein 4; PDBTitle: crystal structure of s.cerevisiae vps4 in the presence of atpgammas 91 d1ofha_ not modelled 67.4 14 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 92 d1ku5a_ not modelled 67.1 14 Fold:Histone-fold Superfamily:Histone-fold Family:Archaeal histone 93 c3ctdB_ not modelled 65.7 14 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative atpase, aaa family; PDBTitle: crystal structure of a putative aaa family atpase from2 prochlorococcus marinus subsp. pastoris 94 d1p3mh_ not modelled 64.5 17 Fold:Histone-fold Superfamily:Histone-fold Family:Nucleosome core histones 95 d1hiob_ not modelled 64.1 17 Fold:Histone-fold Superfamily:Histone-fold Family:Nucleosome core histones 96 d1id3d_ not modelled 63.8 12 Fold:Histone-fold Superfamily:Histone-fold Family:Nucleosome core histones 97 d1tzyb_ not modelled 62.5 17 Fold:Histone-fold Superfamily:Histone-fold Family:Nucleosome core histones 98 c1w5sB_ not modelled 62.4 11 PDB header:replication Chain: B: PDB Molecule:origin recognition complex subunit 2 orc2; PDBTitle: structure of the aeropyrum pernix orc2 protein (adp form) 99 c1s3sA_ not modelled 61.3 16 PDB header:protein binding Chain: A: PDB Molecule:transitional endoplasmic reticulum atpase (ter PDBTitle: crystal structure of aaa atpase p97/vcp nd1 in complex with2 p47 c 100 d3ctda1 not modelled 60.9 14 Fold:post-AAA+ oligomerization domain-like Superfamily:post-AAA+ oligomerization domain-like Family:MgsA/YrvN C-terminal domain-like 101 c2jssA_ not modelled 51.7 12 PDB header:chaperone/nuclear protein Chain: A: PDB Molecule:chimera of histone h2b.1 and histone h2a.z; PDBTitle: nmr structure of chaperone chz1 complexed with histone2 h2a.z-h2b 102 d3bgea1 not modelled 50.0 14 Fold:post-AAA+ oligomerization domain-like Superfamily:post-AAA+ oligomerization domain-like Family:MgsA/YrvN C-terminal domain-like 103 d1um8a_ not modelled 48.9 10 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 104 d1kx5d_ not modelled 45.4 18 Fold:Histone-fold Superfamily:Histone-fold Family:Nucleosome core histones 105 d2b5ea3 not modelled 42.6 12 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:PDI-like 106 c3cf1C_ not modelled 42.5 18 PDB header:transport protein Chain: C: PDB Molecule:transitional endoplasmic reticulum atpase; PDBTitle: structure of p97/vcp in complex with adp/adp.alfx 107 d1d2na_ not modelled 42.0 12 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 108 c2x8aA_ not modelled 40.9 10 PDB header:nuclear protein Chain: A: PDB Molecule:nuclear valosin-containing protein-like; PDBTitle: human nuclear valosin containing protein like (nvl), c-2 terminal aaa-atpase domain 109 d1tafa_ not modelled 40.1 13 Fold:Histone-fold Superfamily:Histone-fold Family:TBP-associated factors, TAFs 110 d1s32d_ not modelled 38.0 17 Fold:Histone-fold Superfamily:Histone-fold Family:Nucleosome core histones 111 d1h3oa_ not modelled 37.9 22 Fold:Histone-fold Superfamily:Histone-fold Family:TBP-associated factors, TAFs 112 c1h3oA_ not modelled 37.9 22 PDB header:transcription/tbp-associated factors Chain: A: PDB Molecule:transcription initiation factor tfiid 135 kda PDBTitle: crystal structure of the human taf4-taf122 (tafii135-tafii20) complex 113 c3iuoA_ not modelled 37.6 9 PDB header:hydrolase Chain: A: PDB Molecule:atp-dependent dna helicase recq; PDBTitle: the crystal structure of the c-terminal domain of the atp-dependent2 dna helicase recq from porphyromonas gingivalis to 1.6a 114 d1eqzb_ not modelled 37.2 17 Fold:Histone-fold Superfamily:Histone-fold Family:Nucleosome core histones 115 d2fnaa2 not modelled 37.1 11 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 116 d3bula1 not modelled 35.5 10 Fold:Methionine synthase domain-like Superfamily:Methionine synthase domain Family:Methionine synthase domain 117 c2krkA_ not modelled 34.8 14 PDB header:protein binding Chain: A: PDB Molecule:26s protease regulatory subunit 8; PDBTitle: solution nmr structure of 26s protease regulatory subunit 82 from h.sapiens, northeast structural genomics consortium3 target target hr3102a 118 d1zl8a1 not modelled 34.6 24 Fold:L27 domain Superfamily:L27 domain Family:L27 domain 119 d1a9xa1 not modelled 32.8 11 Fold:Carbamoyl phosphate synthetase, large subunit connection domain Superfamily:Carbamoyl phosphate synthetase, large subunit connection domain Family:Carbamoyl phosphate synthetase, large subunit connection domain 120 d1y74a1 not modelled 31.8 35 Fold:L27 domain Superfamily:L27 domain Family:L27 domain

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0