Phyre 2 Results for P75718

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Email | l.a.kelley@imperial.ac.uk
Description | P75718
Date | Thu Jan 5 12:13:28 GMT 2012
Unique Job ID | 857c1e6f8329246b

Summary |

Top model
Image coloured by rainbow N → C terminus
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Model (left) based on template c1r22B_
Top template information
PDB header:transcription repressor Chain: B: PDB Molecule:transcriptional repressor smtb; PDBTitle: crystal structure of the cyanobacterial metallothionein2 repressor smtb (c14s/c61s/c121s mutant) in the zn2alpha5-3 form
Confidence and coverage
Confidence: | 96.6% | Coverage: | 57%
57 residues ( 57% of your sequence) have been modelled with 96.6% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
78 residues ( 78%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | T | G | K | E | A | I | I | H | Y | L | G | T | H | K | S | F | C | A | Q | D | V | A | A | V | T | G | A | T | V | T | S | I | N | Q | A | A | A | K | M | A | R | A | G | I | L | V | V | D | G | K | V | W | R | T | V | Y | Y | R | F
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100
Sequence |  | A | T | R | E | E | W | E | G | K | V | S | T | N | L | I | F | K | E | C | R | Q | S | A | A | M | K | R | V | L | R | V | Y | K | R | T | S | M | G | T | Q
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  | ? | ? | ? |  |  | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| c1r22B_ |

### PDB 1r22 chain B

Region: 6 - 64
Aligned: 57
Modelled: 59
Confidence: 96.6%
Identity: 16%
PDB header:transcription repressor
Chain: B: PDB Molecule:transcriptional repressor smtb;
PDBTitle: crystal structure of the cyanobacterial metallothionein2 repressor smtb (c14s/c61s/c121s mutant) in the zn2alpha5-3 form

Phyre2
2 |
| c2oqgA_ |

### PDB 2oqg chain A

Region: 6 - 64
Aligned: 57
Modelled: 59
Confidence: 96.6%
Identity: 23%
PDB header:transcription
Chain: A: PDB Molecule:possible transcriptional regulator, arsr family protein;
PDBTitle: arsr-like transcriptional regulator from rhodococcus sp. rha1

Phyre2
3 |
| c2jscB_ |

### PDB 2jsc chain B

Region: 4 - 64
Aligned: 59
Modelled: 61
Confidence: 96.6%
Identity: 20%
PDB header:transcription
Chain: B: PDB Molecule:transcriptional regulator rv1994c/mt2050;
PDBTitle: nmr structure of the cadmium metal-sensor cmtr from mycobacterium2 tuberculosis

Phyre2
4 |
| c2zkzC_ |

### PDB 2zkz chain C

Region: 6 - 67
Aligned: 60
Modelled: 61
Confidence: 96.5%
Identity: 13%
PDB header:transcription
Chain: C: PDB Molecule:transcriptional repressor pagr;
PDBTitle: crystal structure of the transcriptional repressor pagr of bacillus2 anthracis

Phyre2
5 |
| c3cuoB_ |

### PDB 3cuo chain B

Region: 6 - 67
Aligned: 61
Modelled: 62
Confidence: 96.5%
Identity: 16%
PDB header:transcription regulator
Chain: B: PDB Molecule:uncharacterized hth-type transcriptional regulator ygav;
PDBTitle: crystal structure of the predicted dna-binding transcriptional2 regulator from e. coli

Phyre2
6 |
| d1r1ta_ |

### PDB 1r1t chain A

Region: 6 - 64
Aligned: 57
Modelled: 59
Confidence: 96.4%
Identity: 18%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: "Winged helix" DNA-binding domain
Family: ArsR-like transcriptional regulators

Phyre2
7 |
| d1u2wa1 |

### PDB 1u2w chain A domain 1

Region: 7 - 64
Aligned: 53
Modelled: 58
Confidence: 96.4%
Identity: 23%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: "Winged helix" DNA-binding domain
Family: ArsR-like transcriptional regulators

Phyre2
8 |
| c3pqkD_ |

### PDB 3pqk chain D

Region: 7 - 67
Aligned: 59
Modelled: 61
Confidence: 96.4%
Identity: 14%
PDB header:transcription
Chain: D: PDB Molecule:biofilm growth-associated repressor;
PDBTitle: crystal structure of the transcriptional repressor bigr from xylella2 fastidiosa

Phyre2
9 |
| d2htja1 |

### PDB 2htj chain A domain 1

Region: 4 - 71
Aligned: 68
Modelled: 68
Confidence: 96.4%
Identity: 18%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: "Winged helix" DNA-binding domain
Family: FaeA-like

Phyre2
10 |
| d1r1ua_ |

### PDB 1r1u chain A

Region: 6 - 64
Aligned: 57
Modelled: 59
Confidence: 96.3%
Identity: 5%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: "Winged helix" DNA-binding domain
Family: ArsR-like transcriptional regulators

Phyre2
11 |
| c2kkoB_ |

### PDB 2kko chain B

Region: 4 - 64
Aligned: 59
Modelled: 61
Confidence: 96.3%
Identity: 19%
PDB header:dna binding protein
Chain: B: PDB Molecule:possible transcriptional regulatory protein
PDBTitle: solution nmr structure of the homodimeric winged helix-turn-2 helix dna-binding domain (fragment 1-100) mb0332 from3 mycobacterium bovis, a possible arsr-family transcriptional4 regulator. northeast structural genomics consortium target5 mbr242e.

Phyre2
12 |
| c3jthA_ |

### PDB 3jth chain A

Region: 6 - 67
Aligned: 60
Modelled: 62
Confidence: 96.2%
Identity: 22%
PDB header:transcription
Chain: A: PDB Molecule:transcription activator hlyu;
PDBTitle: crystal structure of a transcriptional regulator hlyu from2 vibrio vulnificus cmcp6

Phyre2
13 |
| c3f6vA_ |

### PDB 3f6v chain A

Region: 7 - 61
Aligned: 53
Modelled: 55
Confidence: 95.9%
Identity: 25%
PDB header:transcription regulator
Chain: A: PDB Molecule:possible transcriptional regulator, arsr family
PDBTitle: crystal structure of possible transcriptional regulator for2 arsenical resistance

Phyre2
14 |
| c3f6oB_ |

### PDB 3f6o chain B

Region: 6 - 60
Aligned: 53
Modelled: 55
Confidence: 95.8%
Identity: 13%
PDB header:transcription regulator
Chain: B: PDB Molecule:probable transcriptional regulator, arsr family
PDBTitle: crystal structure of arsr family transcriptional regulator,2 rha00566

Phyre2
15 |
| d2d1ha1 |

### PDB 2d1h chain A domain 1

Region: 5 - 66
Aligned: 61
Modelled: 0
Confidence: 95.6%
Identity: 15%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: "Winged helix" DNA-binding domain
Family: TrmB-like

Phyre2
16 |
| d1ulya_ |

### PDB 1uly chain A

Region: 7 - 61
Aligned: 54
Modelled: 55
Confidence: 95.4%
Identity: 22%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: "Winged helix" DNA-binding domain
Family: Hypothetical protein PH1932

Phyre2
17 |
| d1z05a1 |

### PDB 1z05 chain A domain 1

Region: 4 - 51
Aligned: 48
Modelled: 48
Confidence: 95.3%
Identity: 8%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: "Winged helix" DNA-binding domain
Family: ROK associated domain

Phyre2
18 |
| d1ub9a_ |

### PDB 1ub9 chain A

Region: 6 - 67
Aligned: 62
Modelled: 62
Confidence: 95.3%
Identity: 15%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: "Winged helix" DNA-binding domain
Family: MarR-like transcriptional regulators

Phyre2
19 |
| d1sfxa_ |

### PDB 1sfx chain A

Region: 7 - 66
Aligned: 60
Modelled: 60
Confidence: 95.2%
Identity: 12%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: "Winged helix" DNA-binding domain
Family: TrmB-like

Phyre2
20 |
| d1biaa1 |

### PDB 1bia chain A domain 1

Region: 4 - 63
Aligned: 56
Modelled: 60
Confidence: 94.8%
Identity: 13%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: "Winged helix" DNA-binding domain
Family: Biotin repressor-like

Phyre2
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| c3eyyA_ |

### PDB 3eyy chain A

Region: 4 - 81
Aligned: 73
Modelled: 73
Confidence: 91.5%
Identity: 12%
PDB header:transport
Chain: A: PDB Molecule:putative iron uptake regulatory protein;
PDBTitle: structural basis for the specialization of nur, a nickel-2 specific fur homologue, in metal sensing and dna3 recognition

Phyre2
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Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | c1r22B_ |
|  | 96.6 | 16 | PDB header:transcription repressor Chain: B: PDB Molecule:transcriptional repressor smtb; PDBTitle: crystal structure of the cyanobacterial metallothionein2 repressor smtb (c14s/c61s/c121s mutant) in the zn2alpha5-3 form
2 | c2oqgA_ |
|  | 96.6 | 23 | PDB header:transcription Chain: A: PDB Molecule:possible transcriptional regulator, arsr family protein; PDBTitle: arsr-like transcriptional regulator from rhodococcus sp. rha1
3 | c2jscB_ |
|  | 96.6 | 20 | PDB header:transcription Chain: B: PDB Molecule:transcriptional regulator rv1994c/mt2050; PDBTitle: nmr structure of the cadmium metal-sensor cmtr from mycobacterium2 tuberculosis
4 | c2zkzC_ |
|  | 96.5 | 13 | PDB header:transcription Chain: C: PDB Molecule:transcriptional repressor pagr; PDBTitle: crystal structure of the transcriptional repressor pagr of bacillus2 anthracis
5 | c3cuoB_ |
|  | 96.5 | 16 | PDB header:transcription regulator Chain: B: PDB Molecule:uncharacterized hth-type transcriptional regulator ygav; PDBTitle: crystal structure of the predicted dna-binding transcriptional2 regulator from e. coli
6 | d1r1ta_ |
|  | 96.4 | 18 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:ArsR-like transcriptional regulators
7 | d1u2wa1 |
|  | 96.4 | 23 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:ArsR-like transcriptional regulators
8 | c3pqkD_ |
|  | 96.4 | 14 | PDB header:transcription Chain: D: PDB Molecule:biofilm growth-associated repressor; PDBTitle: crystal structure of the transcriptional repressor bigr from xylella2 fastidiosa
9 | d2htja1 |
|  | 96.4 | 18 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:FaeA-like
10 | d1r1ua_ |
|  | 96.3 | 5 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:ArsR-like transcriptional regulators
11 | c2kkoB_ |
|  | 96.3 | 19 | PDB header:dna binding protein Chain: B: PDB Molecule:possible transcriptional regulatory protein PDBTitle: solution nmr structure of the homodimeric winged helix-turn-2 helix dna-binding domain (fragment 1-100) mb0332 from3 mycobacterium bovis, a possible arsr-family transcriptional4 regulator. northeast structural genomics consortium target5 mbr242e.
12 | c3jthA_ |
|  | 96.2 | 22 | PDB header:transcription Chain: A: PDB Molecule:transcription activator hlyu; PDBTitle: crystal structure of a transcriptional regulator hlyu from2 vibrio vulnificus cmcp6
13 | c3f6vA_ |
|  | 95.9 | 25 | PDB header:transcription regulator Chain: A: PDB Molecule:possible transcriptional regulator, arsr family PDBTitle: crystal structure of possible transcriptional regulator for2 arsenical resistance
14 | c3f6oB_ |
|  | 95.8 | 13 | PDB header:transcription regulator Chain: B: PDB Molecule:probable transcriptional regulator, arsr family PDBTitle: crystal structure of arsr family transcriptional regulator,2 rha00566
15 | d2d1ha1 |
|  | 95.6 | 15 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:TrmB-like
16 | d1ulya_ |
|  | 95.4 | 22 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Hypothetical protein PH1932
17 | d1z05a1 |
|  | 95.3 | 8 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:ROK associated domain
18 | d1ub9a_ |
|  | 95.3 | 15 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:MarR-like transcriptional regulators
19 | d1sfxa_ |
|  | 95.2 | 12 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:TrmB-like
20 | d1biaa1 |
|  | 94.8 | 13 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Biotin repressor-like
21 | d2etha1 |
| not modelled | 94.6 | 15 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:MarR-like transcriptional regulators
22 | d1lnwa_ |
| not modelled | 93.9 | 10 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:MarR-like transcriptional regulators
23 | c3g3zA_ |
| not modelled | 93.9 | 15 | PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator, marr family; PDBTitle: the structure of nmb1585, a marr family regulator from neisseria2 meningitidis
24 | c2nnnB_ |
| not modelled | 93.9 | 8 | PDB header:transcription Chain: B: PDB Molecule:probable transcriptional regulator; PDBTitle: crystal structure of probable transcriptional regulator from2 pseudomonas aeruginosa
25 | d1s3ja_ |
| not modelled | 93.6 | 15 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:MarR-like transcriptional regulators
26 | d2bv6a1 |
| not modelled | 93.4 | 7 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:MarR-like transcriptional regulators
27 | d2fbia1 |
| not modelled | 93.4 | 16 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:MarR-like transcriptional regulators
28 | d1jgsa_ |
| not modelled | 93.2 | 5 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:MarR-like transcriptional regulators
29 | d1xmka1 |
| not modelled | 93.2 | 29 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Z-DNA binding domain
30 | d1xd7a_ |
| not modelled | 93.2 | 9 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Transcriptional regulator Rrf2
31 | d2a61a1 |
| not modelled | 93.1 | 15 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:MarR-like transcriptional regulators
32 | d1z91a1 |
| not modelled | 93.0 | 8 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:MarR-like transcriptional regulators
33 | d1lj9a_ |
| not modelled | 92.9 | 10 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:MarR-like transcriptional regulators
34 | c3cjnA_ |
| not modelled | 92.8 | 8 | PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional regulator, marr family; PDBTitle: crystal structure of transcriptional regulator, marr family, from2 silicibacter pomeroyi
35 | c3nrvC_ |
| not modelled | 92.8 | 18 | PDB header:transcription regulator Chain: C: PDB Molecule:putative transcriptional regulator (marr/emrr family); PDBTitle: crystal structure of marr/emrr family transcriptional regulator from2 acinetobacter sp. adp1
36 | d1ku9a_ |
| not modelled | 92.6 | 15 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:DNA-binding protein Mj223
37 | c3k0lA_ |
| not modelled | 92.4 | 10 | PDB header:transcription regulator Chain: A: PDB Molecule:repressor protein; PDBTitle: crystal structure of putative marr family transcriptional2 regulator from acinetobacter sp. adp
38 | d2p4wa1 |
| not modelled | 92.3 | 15 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:PF1790-like
39 | c3e6mD_ |
| not modelled | 92.3 | 8 | PDB header:transcription regulator Chain: D: PDB Molecule:marr family transcriptional regulator; PDBTitle: the crystal structure of a marr family transcriptional2 regulator from silicibacter pomeroyi dss.
40 | d1z6ra1 |
| not modelled | 92.1 | 14 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:ROK associated domain
41 | c2nyxB_ |
| not modelled | 92.1 | 11 | PDB header:transcription Chain: B: PDB Molecule:probable transcriptional regulatory protein, rv1404; PDBTitle: crystal structure of rv1404 from mycobacterium tuberculosis
42 | c2gxgA_ |
| not modelled | 92.1 | 15 | PDB header:transcription Chain: A: PDB Molecule:146aa long hypothetical transcriptional regulator; PDBTitle: crystal structure of emrr homolog from hyperthermophilic archaea2 sulfolobus tokodaii strain7
43 | c3bj6B_ |
| not modelled | 91.9 | 16 | PDB header:transcription regulator Chain: B: PDB Molecule:transcriptional regulator, marr family; PDBTitle: crystal structure of marr family transcription regulator sp03579
44 | c3eyyA_ |
|  | 91.5 | 12 | PDB header:transport Chain: A: PDB Molecule:putative iron uptake regulatory protein; PDBTitle: structural basis for the specialization of nur, a nickel-2 specific fur homologue, in metal sensing and dna3 recognition
45 | c2it0A_ |
| not modelled | 91.4 | 18 | PDB header:transcription/dna Chain: A: PDB Molecule:iron-dependent repressor ider; PDBTitle: crystal structure of a two-domain ider-dna complex crystal2 form ii
46 | c3bddD_ |
| not modelled | 91.4 | 9 | PDB header:transcription Chain: D: PDB Molecule:regulatory protein marr; PDBTitle: crystal structure of a putative multiple antibiotic-resistance2 repressor (ssu05_1136) from streptococcus suis 89/1591 at 2.20 a3 resolution
47 | c2y75F_ |
| not modelled | 91.3 | 16 | PDB header:transcription Chain: F: PDB Molecule:hth-type transcriptional regulator cymr; PDBTitle: the structure of cymr (yrzc) the global cysteine regulator2 of b. subtilis
48 | c3f3xA_ |
| not modelled | 91.1 | 15 | PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator, marr family, putative; PDBTitle: crystal structure of the transcriptional regulator bldr2 from sulfolobus solfataricus
49 | c3bpxB_ |
| not modelled | 91.0 | 13 | PDB header:transcription regulator Chain: B: PDB Molecule:transcriptional regulator; PDBTitle: crystal structure of marr
50 | c3eqxB_ |
| not modelled | 91.0 | 7 | PDB header:dna binding protein Chain: B: PDB Molecule:fic domain containing transcriptional regulator; PDBTitle: crystal structure of a fic family protein (so_4266) from shewanella2 oneidensis at 1.6 a resolution
51 | c3r0aB_ |
| not modelled | 90.8 | 10 | PDB header:transcription regulator Chain: B: PDB Molecule:putative transcriptional regulator; PDBTitle: possible transcriptional regulator from methanosarcina mazei go1 (gi2 21227196)
52 | d1g3wa1 |
| not modelled | 90.8 | 18 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Iron-dependent repressor protein
53 | d1okra_ |
| not modelled | 90.5 | 14 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Penicillinase repressor
54 | c3bjaA_ |
| not modelled | 90.1 | 11 | PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional regulator, marr family, putative; PDBTitle: crystal structure of putative marr-like transcription regulator2 (np_978771.1) from bacillus cereus atcc 10987 at 2.38 a resolution
55 | c1f5tA_ |
| not modelled | 90.1 | 17 | PDB header:transcription/dna Chain: A: PDB Molecule:diphtheria toxin repressor; PDBTitle: diphtheria tox repressor (c102d mutant) complexed with2 nickel and dtxr consensus binding sequence
56 | d2isya1 |
| not modelled | 90.0 | 18 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Iron-dependent repressor protein
57 | d3broa1 |
| not modelled | 90.0 | 13 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:MarR-like transcriptional regulators
58 | c2v79B_ |
| not modelled | 89.7 | 13 | PDB header:dna-binding protein Chain: B: PDB Molecule:dna replication protein dnad; PDBTitle: crystal structure of the n-terminal domain of dnad from2 bacillus subtilis
59 | c2x4hA_ |
| not modelled | 89.5 | 11 | PDB header:transcription Chain: A: PDB Molecule:hypothetical protein sso2273; PDBTitle: crystal structure of the hypothetical protein sso2273 from2 sulfolobus solfataricus
60 | c1z6rC_ |
| not modelled | 89.4 | 11 | PDB header:transcription Chain: C: PDB Molecule:mlc protein; PDBTitle: crystal structure of mlc from escherichia coli
61 | d1hsja1 |
| not modelled | 89.2 | 11 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:MarR-like transcriptional regulators
62 | d2fbha1 |
| not modelled | 88.8 | 13 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:MarR-like transcriptional regulators
63 | c2l4aA_ |
| not modelled | 88.7 | 15 | PDB header:dna binding protein Chain: A: PDB Molecule:leucine responsive regulatory protein; PDBTitle: nmr structure of the dna-binding domain of e.coli lrp
64 | c3lwfD_ |
| not modelled | 88.3 | 17 | PDB header:transcription regulator Chain: D: PDB Molecule:putative transcriptional regulator; PDBTitle: crystal structure of putative transcriptional regulator (np_470886.1)2 from listeria innocua at 2.06 a resolution
65 | c2l02B_ |
| not modelled | 88.2 | 20 | PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: solution nmr structure of protein bt2368 from bacteroides2 thetaiotaomicron, northeast structural genomics consortium target3 btr375
66 | c2qwwB_ |
| not modelled | 88.0 | 14 | PDB header:transcription Chain: B: PDB Molecule:transcriptional regulator, marr family; PDBTitle: crystal structure of multiple antibiotic-resistance repressor (marr)2 (yp_013417.1) from listeria monocytogenes 4b f2365 at 2.07 a3 resolution
67 | d2cyya1 |
| not modelled | 87.9 | 17 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Lrp/AsnC-like transcriptional regulator N-terminal domain
68 | d1p4xa2 |
| not modelled | 87.8 | 8 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:MarR-like transcriptional regulators
69 | c3k69A_ |
| not modelled | 87.7 | 19 | PDB header:transcription Chain: A: PDB Molecule:putative transcription regulator; PDBTitle: crystal structure of a putative transcriptional regulator (lp_0360)2 from lactobacillus plantarum at 1.95 a resolution
70 | d1qgpa_ |
| not modelled | 87.5 | 28 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Z-DNA binding domain
71 | c1z05A_ |
| not modelled | 87.2 | 9 | PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator, rok family; PDBTitle: crystal structure of the rok family transcriptional regulator, homolog2 of e.coli mlc protein.
72 | d2ns0a1 |
| not modelled | 87.2 | 31 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:RHA1 ro06458-like
73 | d2frha1 |
| not modelled | 87.2 | 7 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:MarR-like transcriptional regulators
74 | c2zmeB_ |
| not modelled | 87.1 | 17 | PDB header:protein transport Chain: B: PDB Molecule:vacuolar protein-sorting-associated protein 36; PDBTitle: integrated structural and functional model of the human escrt-ii2 complex
75 | c1j5yA_ |
| not modelled | 87.1 | 19 | PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator, biotin repressor family; PDBTitle: crystal structure of transcriptional regulator (tm1602) from2 thermotoga maritima at 2.3 a resolution
76 | d1p4xa1 |
| not modelled | 86.9 | 13 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:MarR-like transcriptional regulators
77 | d1ylfa1 |
| not modelled | 86.7 | 15 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Transcriptional regulator Rrf2
78 | c2fa5B_ |
| not modelled | 86.6 | 19 | PDB header:transcription Chain: B: PDB Molecule:transcriptional regulator marr/emrr family; PDBTitle: the crystal structure of an unliganded multiple antibiotic-2 resistance repressor (marr) from xanthomonas campestris
79 | c3s2wB_ |
| not modelled | 86.6 | 9 | PDB header:transcription regulator Chain: B: PDB Molecule:transcriptional regulator, marr family; PDBTitle: the crystal structure of a marr transcriptional regulator from2 methanosarcina mazei go1
80 | d2cfxa1 |
| not modelled | 86.6 | 13 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Lrp/AsnC-like transcriptional regulator N-terminal domain
81 | d1mzba_ |
| not modelled | 86.5 | 14 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:FUR-like
82 | c2h09A_ |
| not modelled | 86.3 | 15 | PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator mntr; PDBTitle: crystal structure of diphtheria toxin repressor like protein2 from e. coli
83 | d1i5za1 |
| not modelled | 86.3 | 10 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:CAP C-terminal domain-like
84 | d3ctaa1 |
| not modelled | 86.2 | 11 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:MarR-like transcriptional regulators
85 | c3oopA_ |
| not modelled | 85.8 | 10 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:lin2960 protein; PDBTitle: the structure of a protein with unknown function from listeria innocua2 clip11262
86 | d1j5ya1 |
| not modelled | 85.8 | 21 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Biotin repressor-like
87 | d2gaua1 |
| not modelled | 85.6 | 18 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:CAP C-terminal domain-like
88 | c3nqoB_ |
| not modelled | 85.6 | 15 | PDB header:transcription Chain: B: PDB Molecule:marr-family transcriptional regulator; PDBTitle: crystal structure of a marr family transcriptional regulator (cd1569)2 from clostridium difficile 630 at 2.20 a resolution
89 | d2oz6a1 |
| not modelled | 85.4 | 15 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:CAP C-terminal domain-like
90 | d2coha1 |
| not modelled | 85.3 | 15 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:CAP C-terminal domain-like
91 | c2rdpA_ |
| not modelled | 85.1 | 7 | PDB header:transcription Chain: A: PDB Molecule:putative transcriptional regulator marr; PDBTitle: the structure of a marr family protein from bacillus2 stearothermophilus
92 | d3deua1 |
| not modelled | 84.9 | 11 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:MarR-like transcriptional regulators
93 | d1i1ga1 |
| not modelled | 84.5 | 15 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Lrp/AsnC-like transcriptional regulator N-terminal domain
94 | c1g3wA_ |
| not modelled | 84.5 | 18 | PDB header:gene regulation Chain: A: PDB Molecule:diphtheria toxin repressor; PDBTitle: cd-cys102ser dtxr
95 | c2zmeA_ |
| not modelled | 84.5 | 9 | PDB header:protein transport Chain: A: PDB Molecule:vacuolar-sorting protein snf8; PDBTitle: integrated structural and functional model of the human escrt-ii2 complex
96 | c1p4xA_ |
| not modelled | 84.5 | 11 | PDB header:transcription Chain: A: PDB Molecule:staphylococcal accessory regulator a homologue; PDBTitle: crystal structure of sars protein from staphylococcus aureus
97 | d2cg4a1 |
| not modelled | 84.3 | 24 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Lrp/AsnC-like transcriptional regulator N-terminal domain
98 | c3df8A_ |
| not modelled | 84.3 | 16 | PDB header:transcription Chain: A: PDB Molecule:possible hxlr family transcriptional factor; PDBTitle: the crystal structure of a possible hxlr family transcriptional factor2 from thermoplasma volcanium gss1
99 | c3cuqA_ |
| not modelled | 84.3 | 9 | PDB header:protein transport Chain: A: PDB Molecule:vacuolar-sorting protein snf8; PDBTitle: integrated structural and functional model of the human escrt-ii2 complex
100 | c2fxaB_ |
| not modelled | 84.2 | 16 | PDB header:transcription Chain: B: PDB Molecule:protease production regulatory protein hpr; PDBTitle: structure of the protease production regulatory protein hpr from2 bacillus subtilis.
101 | d1ft9a1 |
| not modelled | 83.9 | 17 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:CAP C-terminal domain-like
102 | c2w57A_ |
| not modelled | 83.6 | 11 | PDB header:metal transport Chain: A: PDB Molecule:ferric uptake regulation protein; PDBTitle: crystal structure of the vibrio cholerae ferric uptake2 regulator (fur) reveals structural rearrangement of the3 dna-binding domains
103 | c2xigA_ |
| not modelled | 83.3 | 10 | PDB header:transcription Chain: A: PDB Molecule:ferric uptake regulation protein; PDBTitle: the structure of the helicobacter pylori ferric uptake2 regulator fur reveals three functional metal binding sites
104 | c2l01A_ |
| not modelled | 83.2 | 11 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution nmr structure of protein bvu3908 from bacteroides vulgatus,2 northeast structural genomics consortium target bvr153
105 | d1mkma1 |
| not modelled | 83.2 | 13 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Transcriptional regulator IclR, N-terminal domain
106 | c3i4pA_ |
| not modelled | 82.9 | 20 | PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional regulator, asnc family; PDBTitle: crystal structure of asnc family transcriptional regulator from2 agrobacterium tumefaciens
107 | d2ev0a1 |
| not modelled | 82.6 | 17 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Iron-dependent repressor protein
108 | c1u5tA_ |
| not modelled | 82.5 | 16 | PDB header:transport protein Chain: A: PDB Molecule:appears to be functionally related to snf7; PDBTitle: structure of the escrt-ii endosomal trafficking complex
109 | c3e6dA_ |
| not modelled | 82.5 | 15 | PDB header:transcription regulation Chain: A: PDB Molecule:cyclic nucleotide-binding protein; PDBTitle: crystal structure of cprk c200s
110 | c2o03A_ |
| not modelled | 82.4 | 19 | PDB header:gene regulation Chain: A: PDB Molecule:probable zinc uptake regulation protein furb; PDBTitle: crystal structure of furb from m. tuberculosis- a zinc uptake2 regulator
111 | c1i1gA_ |
| not modelled | 82.4 | 17 | PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator lrpa; PDBTitle: crystal structure of the lrp-like transcriptional regulator from the2 archaeon pyrococcus furiosus
112 | d2gxba1 |
| not modelled | 82.4 | 28 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Z-DNA binding domain
113 | c2dbbA_ |
| not modelled | 82.0 | 17 | PDB header:transcriptional regulator Chain: A: PDB Molecule:putative hth-type transcriptional regulator ph0061; PDBTitle: crystal structure of ph0061
114 | c2xroE_ |
| not modelled | 81.8 | 11 | PDB header:dna-binding protein/dna Chain: E: PDB Molecule:hth-type transcriptional regulator ttgv; PDBTitle: crystal structure of ttgv in complex with its dna operator
115 | c2pexA_ |
| not modelled | 81.4 | 8 | PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional regulator ohrr; PDBTitle: structure of reduced c22s ohrr from xanthamonas campestris
116 | c2cg4B_ |
| not modelled | 81.2 | 25 | PDB header:transcription Chain: B: PDB Molecule:regulatory protein asnc; PDBTitle: structure of e.coli asnc
117 | c3hrmA_ |
| not modelled | 80.9 | 3 | PDB header:transcription regulator Chain: A: PDB Molecule:hth-type transcriptional regulator sarz; PDBTitle: crystal structure of staphylococcus aureus protein sarz in sulfenic2 acid form
118 | d1qbjc_ |
| not modelled | 80.6 | 28 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Z-DNA binding domain
119 | c2fe3B_ |
| not modelled | 80.5 | 16 | PDB header:dna binding protein Chain: B: PDB Molecule:peroxide operon regulator; PDBTitle: the crystal structure of bacillus subtilis perr-zn reveals a novel2 zn(cys)4 structural redox switch
120 | c3ctaA_ |
| not modelled | 80.4 | 9 | PDB header:transferase Chain: A: PDB Molecule:riboflavin kinase; PDBTitle: crystal structure of riboflavin kinase from thermoplasma2 acidophilum

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0