Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP0A7E1
DateThu Jan 5 11:05:27 GMT 2012
Unique Job ID84241962d0a5a112

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1f76a_
Top template information
Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
Confidence and coverage
Confidence:100.0% Coverage:100%
336 residues (100% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MYYPFVRKALFQLDPERAHEFTFQQLRRITGTPFEALVRQKVPAKPVNCMGLTFKNPLGL
Secondary structure 
SS confidence 
Disorder  ??
?
??
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  AAGLDKDGECIDALGAMGFGSIEIGTVTPRPQPGNDKPRLFRLVDAEGLINRMGFNNLGV
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  DNLVENVKKAHYDGVLGINIGKNKDTPVEQGKDDYLICMEKIYAYAGYIAINISSPNTPG
Secondary structure 
SS confidence 
Disorder 
??
?
??
?
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  LRTLQYGEALDDLLTAIKNKQNDLQAMHHKYVPIAVKIAPDLSEEELIQVADSLVRHNID
Secondary structure 
SS confidence 
Disorder  ??????
??
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  GVIATNTTLDRSLVQGMKNCDQTGGLSGRPLQLKSTEIIRRLSLELNGRLPIIGVGGIDS
Secondary structure 
SS confidence 
Disorder 
???????????
Disorder confidence 
 
   .........310.........320.........330......
Sequence  VIAAREKIAAGASLVQIYSGFIFKGPPLIKEIVTHI
Secondary structure 
SS confidence 
Disorder 
??
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1f76 chain A

3D model

Region: 1 - 336
Aligned: 336
Modelled: 335
Confidence: 100.0%
Identity: 98%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 1tv5 chain A

3D model

Region: 1 - 336
Aligned: 329
Modelled: 336
Confidence: 100.0%
Identity: 41%
PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydroorotate dehydrogenase homolog, mitochondrial;
PDBTitle: plasmodium falciparum dihydroorotate dehydrogenase with a bound2 inhibitor

Phyre2

PDB 1tv5 chain A domain 1

3D model

Region: 1 - 336
Aligned: 329
Modelled: 336
Confidence: 100.0%
Identity: 41%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 2fpt chain A

3D model

Region: 1 - 336
Aligned: 326
Modelled: 336
Confidence: 100.0%
Identity: 41%
PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydroorotate dehydrogenase, mitochondrial;
PDBTitle: dual binding mode of a novel series of dhodh inhibitors

Phyre2

PDB 1d3g chain A

3D model

Region: 1 - 336
Aligned: 322
Modelled: 336
Confidence: 100.0%
Identity: 40%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 1uum chain A

3D model

Region: 2 - 336
Aligned: 319
Modelled: 324
Confidence: 100.0%
Identity: 39%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 1gth chain D

3D model

Region: 14 - 336
Aligned: 304
Modelled: 317
Confidence: 100.0%
Identity: 22%
PDB header:oxidoreductase
Chain: D: PDB Molecule:dihydropyrimidine dehydrogenase;
PDBTitle: dihydropyrimidine dehydrogenase (dpd) from pig, ternary2 complex with nadph and 5-iodouracil

Phyre2

PDB 3oix chain A

3D model

Region: 43 - 336
Aligned: 273
Modelled: 287
Confidence: 100.0%
Identity: 24%
PDB header:oxidoreductase
Chain: A: PDB Molecule:putative dihydroorotate dehydrogenase; dihydroorotate
PDBTitle: crystal structure of the putative dihydroorotate dehydrogenase from2 streptococcus mutans

Phyre2

PDB 2b4g chain A domain 1

3D model

Region: 44 - 336
Aligned: 278
Modelled: 293
Confidence: 100.0%
Identity: 24%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 1jub chain A

3D model

Region: 45 - 336
Aligned: 277
Modelled: 292
Confidence: 100.0%
Identity: 24%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 2e77 chain B

3D model

Region: 14 - 336
Aligned: 280
Modelled: 306
Confidence: 100.0%
Identity: 16%
PDB header:oxidoreductase
Chain: B: PDB Molecule:lactate oxidase;
PDBTitle: crystal structure of l-lactate oxidase with pyruvate complex

Phyre2

PDB 2rdu chain A

3D model

Region: 14 - 336
Aligned: 289
Modelled: 306
Confidence: 100.0%
Identity: 13%
PDB header:oxidoreductase
Chain: A: PDB Molecule:hydroxyacid oxidase 1;
PDBTitle: crystal structure of human glycolate oxidase in complex with2 glyoxylate

Phyre2

PDB 1gox chain A

3D model

Region: 14 - 336
Aligned: 277
Modelled: 306
Confidence: 100.0%
Identity: 16%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 3gye chain A

3D model

Region: 43 - 336
Aligned: 267
Modelled: 281
Confidence: 100.0%
Identity: 23%
PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydroorotate dehydrogenase, putative;
PDBTitle: didydroorotate dehydrogenase from leishmania major

Phyre2

PDB 1kbi chain B

3D model

Region: 14 - 336
Aligned: 273
Modelled: 299
Confidence: 100.0%
Identity: 17%
PDB header:oxidoreductase
Chain: B: PDB Molecule:cytochrome b2;
PDBTitle: crystallographic study of the recombinant flavin-binding domain of2 baker's yeast flavocytochrome b2: comparison with the intact wild-3 type enzyme

Phyre2

PDB 2a7n chain A

3D model

Region: 14 - 336
Aligned: 287
Modelled: 300
Confidence: 100.0%
Identity: 14%
PDB header:oxidoreductase
Chain: A: PDB Molecule:l(+)-mandelate dehydrogenase;
PDBTitle: crystal structure of the g81a mutant of the active chimera of (s)-2 mandelate dehydrogenase

Phyre2

PDB 1p4c chain A

3D model

Region: 1 - 336
Aligned: 300
Modelled: 319
Confidence: 100.0%
Identity: 14%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 1kbi chain A domain 1

3D model

Region: 14 - 336
Aligned: 274
Modelled: 306
Confidence: 100.0%
Identity: 17%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 1tb3 chain A domain 1

3D model

Region: 14 - 336
Aligned: 263
Modelled: 287
Confidence: 100.0%
Identity: 15%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 1ep3 chain A

3D model

Region: 39 - 336
Aligned: 275
Modelled: 298
Confidence: 100.0%
Identity: 27%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2
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d1f76a_
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c1tv5A_
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d1tv5a1
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c2fptA_
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d1d3ga_
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d1uuma_
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c1gthD_
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c3oixA_
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d2b4ga1
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d1juba_
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c2e77B_
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c2rduA_
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d1goxa_
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c3gyeA_
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c1kbiB_
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c2a7nA_
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d1p4ca_
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d1kbia1
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1f76a_
100.0 98 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
2c1tv5A_
100.0 41 PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydroorotate dehydrogenase homolog, mitochondrial;
PDBTitle: plasmodium falciparum dihydroorotate dehydrogenase with a bound2 inhibitor
3d1tv5a1
100.0 41 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
4c2fptA_
100.0 41 PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydroorotate dehydrogenase, mitochondrial;
PDBTitle: dual binding mode of a novel series of dhodh inhibitors
5d1d3ga_
100.0 40 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
6d1uuma_
100.0 39 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
7c1gthD_
100.0 22 PDB header:oxidoreductase
Chain: D: PDB Molecule:dihydropyrimidine dehydrogenase;
PDBTitle: dihydropyrimidine dehydrogenase (dpd) from pig, ternary2 complex with nadph and 5-iodouracil
8c3oixA_
100.0 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative dihydroorotate dehydrogenase; dihydroorotate
PDBTitle: crystal structure of the putative dihydroorotate dehydrogenase from2 streptococcus mutans
9d2b4ga1
100.0 24 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
10d1juba_
100.0 24 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
11c2e77B_
100.0 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:lactate oxidase;
PDBTitle: crystal structure of l-lactate oxidase with pyruvate complex
12c2rduA_
100.0 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:hydroxyacid oxidase 1;
PDBTitle: crystal structure of human glycolate oxidase in complex with2 glyoxylate
13d1goxa_
100.0 16 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
14c3gyeA_
100.0 23 PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydroorotate dehydrogenase, putative;
PDBTitle: didydroorotate dehydrogenase from leishmania major
15c1kbiB_
100.0 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:cytochrome b2;
PDBTitle: crystallographic study of the recombinant flavin-binding domain of2 baker's yeast flavocytochrome b2: comparison with the intact wild-3 type enzyme
16c2a7nA_
100.0 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:l(+)-mandelate dehydrogenase;
PDBTitle: crystal structure of the g81a mutant of the active chimera of (s)-2 mandelate dehydrogenase
17d1p4ca_
100.0 14 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
18d1kbia1
100.0 17 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
19d1tb3a1
100.0 15 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
20d1ep3a_
100.0 27 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
21d1gtea2
not modelled 100.0 24 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
22c2zrvC_
not modelled 100.0 13 PDB header:isomerase
Chain: C: PDB Molecule:isopentenyl-diphosphate delta-isomerase;
PDBTitle: crystal structure of sulfolobus shibatae isopentenyl2 diphosphate isomerase in complex with reduced fmn.
23d1vcfa1
not modelled 100.0 19 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
24d1p0ka_
not modelled 100.0 21 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
25c1jcnA_
not modelled 100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine monophosphate dehydrogenase i;
PDBTitle: binary complex of human type-i inosine monophosphate dehydrogenase2 with 6-cl-imp
26c3khjE_
not modelled 100.0 21 PDB header:oxidoreductase
Chain: E: PDB Molecule:inosine-5-monophosphate dehydrogenase;
PDBTitle: c. parvum inosine monophosphate dehydrogenase bound by inhibitor c64
27d1jcna1
not modelled 100.0 20 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
28d1eepa_
not modelled 99.9 20 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
29c3gr7A_
not modelled 99.9 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadph dehydrogenase;
PDBTitle: structure of oye from geobacillus kaustophilus, hexagonal2 crystal form
30c1vrdA_
not modelled 99.9 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine-5'-monophosphate dehydrogenase;
PDBTitle: crystal structure of inosine-5'-monophosphate dehydrogenase (tm1347)2 from thermotoga maritima at 2.18 a resolution
31c2qr6A_
not modelled 99.9 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:imp dehydrogenase/gmp reductase;
PDBTitle: crystal structure of imp dehydrogenase/gmp reductase-like protein2 (np_599840.1) from corynebacterium glutamicum atcc 13032 kitasato at3 1.50 a resolution
32d1ps9a1
not modelled 99.9 16 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
33d1vrda1
not modelled 99.9 21 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
34c1ypfB_
not modelled 99.9 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:gmp reductase;
PDBTitle: crystal structure of guac (ba5705) from bacillus anthracis at 1.8 a2 resolution
35d1vhna_
not modelled 99.9 17 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
36c3hf3A_
not modelled 99.9 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:chromate reductase;
PDBTitle: old yellow enzyme from thermus scotoductus sa-01
37d1jr1a1
not modelled 99.9 21 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
38c3ffsC_
not modelled 99.9 18 PDB header:oxidoreductase
Chain: C: PDB Molecule:inosine-5-monophosphate dehydrogenase;
PDBTitle: the crystal structure of cryptosporidium parvum inosine-5'-2 monophosphate dehydrogenase
39c3r2gA_
not modelled 99.9 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine 5'-monophosphate dehydrogenase;
PDBTitle: crystal structure of inosine 5' monophosphate dehydrogenase from2 legionella pneumophila
40c2h90A_
not modelled 99.9 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:xenobiotic reductase a;
PDBTitle: xenobiotic reductase a in complex with coumarin
41c1me9A_
not modelled 99.9 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine-5'-monophosphate dehydrogenase;
PDBTitle: inosine monophosphate dehydrogenase (impdh) from2 tritrichomonas foetus with imp bound
42d1zfja1
not modelled 99.9 18 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
43d2cu0a1
not modelled 99.9 17 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
44c2cu0B_
not modelled 99.9 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:inosine-5'-monophosphate dehydrogenase;
PDBTitle: crystal structure of inosine-5'-monophosphate dehydrogenase from2 pyrococcus horikoshii ot3
45c3b0vD_
not modelled 99.9 17 PDB header:oxidoreductase/rna
Chain: D: PDB Molecule:trna-dihydrouridine synthase;
PDBTitle: trna-dihydrouridine synthase from thermus thermophilus in complex with2 trna
46d1djqa1
not modelled 99.9 16 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
47c2cdh1_
not modelled 99.9 22 PDB header:transferase
Chain: 1: PDB Molecule:enoyl reductase;
PDBTitle: architecture of the thermomyces lanuginosus fungal fatty2 acid synthase at 5 angstrom resolution.
48c3kruC_
not modelled 99.9 14 PDB header:oxidoreductase
Chain: C: PDB Molecule:nadh:flavin oxidoreductase/nadh oxidase;
PDBTitle: crystal structure of the thermostable old yellow enzyme from2 thermoanaerobacter pseudethanolicus e39
49d1pvna1
not modelled 99.9 16 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
50c2a7rD_
not modelled 99.9 10 PDB header:oxidoreductase
Chain: D: PDB Molecule:gmp reductase 2;
PDBTitle: crystal structure of human guanosine monophosphate2 reductase 2 (gmpr2)
51c1ps9A_
not modelled 99.9 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:2,4-dienoyl-coa reductase;
PDBTitle: the crystal structure and reaction mechanism of e. coli 2,4-2 dienoyl coa reductase
52c1djnB_
not modelled 99.9 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:trimethylamine dehydrogenase;
PDBTitle: structural and biochemical characterization of recombinant wild type2 trimethylamine dehydrogenase from methylophilus methylotrophus (sp.3 w3a1)
53d1z41a1
not modelled 99.9 18 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
54d1geqa_
not modelled 99.9 19 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
55c3k30B_
not modelled 99.9 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:histamine dehydrogenase;
PDBTitle: histamine dehydrogenase from nocardiodes simplex
56d1vyra_
not modelled 99.8 16 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
57c2htmB_
not modelled 99.8 15 PDB header:biosynthetic protein
Chain: B: PDB Molecule:thiazole biosynthesis protein thig;
PDBTitle: crystal structure of ttha0676 from thermus thermophilus hb8
58d1gwja_
not modelled 99.8 15 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
59c2gjlA_
not modelled 99.8 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:hypothetical protein pa1024;
PDBTitle: crystal structure of 2-nitropropane dioxygenase
60c3gkaB_
not modelled 99.8 19 PDB header:oxidoreductase
Chain: B: PDB Molecule:n-ethylmaleimide reductase;
PDBTitle: crystal structure of n-ethylmaleimidine reductase from2 burkholderia pseudomallei
61c3bw2A_
not modelled 99.8 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-nitropropane dioxygenase;
PDBTitle: crystal structures and site-directed mutagenesis study of nitroalkane2 oxidase from streptomyces ansochromogenes
62c3bo9B_
not modelled 99.8 19 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative nitroalkan dioxygenase;
PDBTitle: crystal structure of putative nitroalkan dioxygenase (tm0800) from2 thermotoga maritima at 2.71 a resolution
63c2gq8A_
not modelled 99.7 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase, fmn-binding;
PDBTitle: structure of sye1, an oye homologue from s. ondeidensis, in complex2 with p-hydroxyacetophenone
64c2z6jB_
not modelled 99.7 21 PDB header:oxidoreductase
Chain: B: PDB Molecule:trans-2-enoyl-acp reductase ii;
PDBTitle: crystal structure of s. pneumoniae enoyl-acyl carrier2 protein reductase (fabk) in complex with an inhibitor
65d1vjia_
not modelled 99.7 14 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
66d1icpa_
not modelled 99.7 15 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
67d1oyaa_
not modelled 99.7 15 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
68c3l5aA_
not modelled 99.7 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadh/flavin oxidoreductase/nadh oxidase;
PDBTitle: crystal structure of a probable nadh-dependent flavin oxidoreductase2 from staphylococcus aureus
69d1rd5a_
not modelled 99.7 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
70d1q45a_
not modelled 99.6 17 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
71c3atyA_
not modelled 99.6 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:prostaglandin f2a synthase;
PDBTitle: crystal structure of tcoye
72c1zfjA_
not modelled 99.6 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine monophosphate dehydrogenase;
PDBTitle: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from2 streptococcus pyogenes
73d1y0ea_
not modelled 99.6 17 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:NanE-like
74d1xm3a_
not modelled 99.5 15 Fold:TIM beta/alpha-barrel
Superfamily:ThiG-like
Family:ThiG-like
75d1ofda2
not modelled 99.4 18 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
76d1yxya1
not modelled 99.4 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:NanE-like
77d1qopa_
not modelled 99.3 21 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
78d1ea0a2
not modelled 99.3 17 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
79c3q58A_
not modelled 99.3 17 PDB header:isomerase
Chain: A: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase;
PDBTitle: structure of n-acetylmannosamine-6-phosphate epimerase from salmonella2 enterica
80c2c3zA_
not modelled 99.3 15 PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus
81c3qjaA_
not modelled 99.3 16 PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of the mycobacterium tuberculosis indole-3-glycerol2 phosphate synthase (trpc) in apo form
82d1wv2a_
not modelled 99.3 16 Fold:TIM beta/alpha-barrel
Superfamily:ThiG-like
Family:ThiG-like
83d1xcfa_
not modelled 99.2 20 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
84d1a53a_
not modelled 99.2 18 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
85c3tdmD_
not modelled 99.2 26 PDB header:de novo protein
Chain: D: PDB Molecule:computationally designed two-fold symmetric tim-barrel
PDBTitle: computationally designed tim-barrel protein, halfflr
86c3igsB_
not modelled 99.2 18 PDB header:isomerase
Chain: B: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase 2;
PDBTitle: structure of the salmonella enterica n-acetylmannosamine-6-phosphate2 2-epimerase
87d1ka9f_
not modelled 99.2 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
88c3navB_
not modelled 99.1 23 PDB header:lyase
Chain: B: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: crystal structure of an alpha subunit of tryptophan synthase from2 vibrio cholerae o1 biovar el tor str. n16961
89c2vdcF_
not modelled 99.1 17 PDB header:oxidoreductase
Chain: F: PDB Molecule:glutamate synthase [nadph] large chain;
PDBTitle: the 9.5 a resolution structure of glutamate synthase from2 cryo-electron microscopy and its oligomerization behavior3 in solution: functional implications.
90c2ekcA_
not modelled 99.1 14 PDB header:lyase
Chain: A: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: structural study of project id aq_1548 from aquifex aeolicus vf5
91c2w6rA_
not modelled 99.1 23 PDB header:lyase
Chain: A: PDB Molecule:imidazole glycerol phosphate synthase subunit
PDBTitle: crystal structure of an artificial (ba)8-barrel protein2 designed from identical half barrels
92c1lm1A_
not modelled 99.1 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:ferredoxin-dependent glutamate synthase;
PDBTitle: structural studies on the synchronization of catalytic centers in2 glutamate synthase: native enzyme
93c3thaB_
not modelled 99.0 17 PDB header:lyase
Chain: B: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: tryptophan synthase subunit alpha from campylobacter jejuni.
94d1mzha_
not modelled 98.9 21 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
95d1j5ta_
not modelled 98.9 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
96d1o0ya_
not modelled 98.8 18 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
97d1thfd_
not modelled 98.8 24 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
98d1n7ka_
not modelled 98.8 23 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
99d1h5ya_
not modelled 98.8 26 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
100d1piia2
not modelled 98.8 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
101c3oa3A_
not modelled 98.8 17 PDB header:lyase
Chain: A: PDB Molecule:aldolase;
PDBTitle: crystal structure of a putative deoxyribose-phosphate aldolase from2 coccidioides immitis
102c1znnF_
not modelled 98.8 17 PDB header:biosynthetic protein
Chain: F: PDB Molecule:plp synthase;
PDBTitle: structure of the synthase subunit of plp synthase
103c2y85D_
not modelled 98.7 17 PDB header:isomerase
Chain: D: PDB Molecule:phosphoribosyl isomerase a;
PDBTitle: crystal structure of mycobacterium tuberculosis phosphoribosyl2 isomerase with bound rcdrp
104c3ng3A_
not modelled 98.7 18 PDB header:lyase
Chain: A: PDB Molecule:deoxyribose-phosphate aldolase;
PDBTitle: crystal structure of deoxyribose phosphate aldolase from mycobacterium2 avium 104 in a schiff base with an unknown aldehyde
105d1znna1
not modelled 98.7 18 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:PdxS-like
106d1jvna1
not modelled 98.7 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
107c3ngjC_
not modelled 98.7 19 PDB header:lyase
Chain: C: PDB Molecule:deoxyribose-phosphate aldolase;
PDBTitle: crystal structure of a putative deoxyribose-phosphate aldolase from2 entamoeba histolytica
108d1vc4a_
not modelled 98.7 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
109d1ub3a_
not modelled 98.7 20 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
110d1wbha1
not modelled 98.6 17 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
111d1rpxa_
not modelled 98.6 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
112d1wa3a1
not modelled 98.6 11 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
113c2v82A_
not modelled 98.6 13 PDB header:lyase
Chain: A: PDB Molecule:2-dehydro-3-deoxy-6-phosphogalactonate aldolase;
PDBTitle: kdpgal complexed to kdpgal
114c1jvnB_
not modelled 98.6 14 PDB header:transferase
Chain: B: PDB Molecule:bifunctional histidine biosynthesis protein hishf;
PDBTitle: crystal structure of imidazole glycerol phosphate synthase: a tunnel2 through a (beta/alpha)8 barrel joins two active sites
115d1i4na_
not modelled 98.6 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
116d1mxsa_
not modelled 98.5 16 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
117d1hg3a_
not modelled 98.5 13 Fold:TIM beta/alpha-barrel
Superfamily:Triosephosphate isomerase (TIM)
Family:Triosephosphate isomerase (TIM)
118d1qo2a_
not modelled 98.5 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
119c1piiA_
not modelled 98.5 18 PDB header:bifunctional(isomerase and synthase)
Chain: A: PDB Molecule:n-(5'phosphoribosyl)anthranilate isomerase;
PDBTitle: three-dimensional structure of the bifunctional enzyme2 phosphoribosylanthranilate isomerase:3 indoleglycerolphosphate synthase from escherichia coli4 refined at 2.0 angstroms resolution
120d2flia1
not modelled 98.5 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0