BLASTP 2.2.22 [Sep-27-2009]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= batch____
         (275 letters)

Database: uniref50.fasta 
           3,077,464 sequences; 1,040,396,356 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P0AEW5 Protein icc n=161 Tax=Gammaproteobacteria RepID=...   565   e-160
UniRef50_P44685 Protein icc homolog n=27 Tax=Pasteurellaceae Rep...   304   2e-81
UniRef50_D2U2B8 Cyclic 3',5'-adenosine monophosphate phosphodies...   303   6e-81
UniRef50_C6AKV1 Icc n=6 Tax=Pasteurellaceae RepID=C6AKV1_AGGAN        294   3e-78
UniRef50_C4L9C4 Calcineurin phosphoesterase domain protein n=3 T...   283   3e-75
UniRef50_Q7MNX9 Cyclic AMP phosphodiesterase n=60 Tax=Gammaprote...   278   1e-73
UniRef50_A6F721 Icc protein-like protein n=1 Tax=Moritella sp. P...   262   8e-69
UniRef50_A1SZX9 Cyclic AMP phosphodiesterase n=2 Tax=Psychromona...   246   6e-64
UniRef50_Q12J78 Metallophosphoesterase n=21 Tax=Shewanella RepID...   230   3e-59
UniRef50_Q2S9N2 Predicted phosphohydrolase n=1 Tax=Hahella cheju...   214   2e-54
UniRef50_Q1N2L2 Metallophosphoesterase n=1 Tax=Bermanella marisr...   213   7e-54
UniRef50_A4B8Z0 Putative uncharacterized protein n=1 Tax=Reineke...   211   3e-53
UniRef50_Q4KJ96 Cyclic AMP phosphodiesterase n=25 Tax=Bacteria R...   209   7e-53
UniRef50_A1TYT4 Calcineurin phosphoesterase C-terminal domain pr...   207   3e-52
UniRef50_Q0VLK4 Icc protein, putative n=2 Tax=Alcanivorax RepID=...   204   3e-51
UniRef50_A4BSE9 Ser/Thr protein phosphatase n=1 Tax=Nitrococcus ...   201   3e-50
UniRef50_A0Y9K0 Cyclic AMP phosphodiesterase n=1 Tax=marine gamm...   199   7e-50
UniRef50_B8HUH6 Metallophosphoesterase n=2 Tax=Chroococcales Rep...   195   1e-48
UniRef50_Q21NU3 Metallophosphoesterase n=3 Tax=Gammaproteobacter...   192   7e-48
UniRef50_B0C4F0 3',5'-cyclic-nucleotide phosphodiesterase n=1 Ta...   191   3e-47
UniRef50_A0YY40 3',5'-cyclic-nucleotide phosphodiesterase n=1 Ta...   191   3e-47
UniRef50_Q606D3 Cyclic AMP phosphodiesterase n=1 Tax=Methylococc...   190   4e-47
UniRef50_A4A8X3 Icc protein n=2 Tax=unclassified Gammaproteobact...   189   8e-47
UniRef50_UPI0001698C6A Calcineurin phosphoesterase C-terminal do...   187   3e-46
UniRef50_Q8YLG0 3',5'-cyclic-nucleotide phosphodiesterase n=3 Ta...   184   4e-45
UniRef50_C7R6J1 Metallophosphoesterase n=1 Tax=Kangiella koreens...   181   2e-44
UniRef50_B8KUM1 Cyclic AMP phosphodiesterase n=1 Tax=gamma prote...   173   6e-42
UniRef50_Q1YUP4 CAMP phosphodiesterase n=1 Tax=gamma proteobacte...   171   2e-41
UniRef50_B8GLR4 Icc protein n=1 Tax=Thioalkalivibrio sp. HL-EbGR...   170   5e-41
UniRef50_Q1C384 Regulator of lacZ n=8 Tax=Enterobacteriaceae Rep...   169   9e-41
UniRef50_C5SEA9 Calcineurin phosphoesterase domain protein n=1 T...   168   1e-40
UniRef50_Q2JPZ0 Icc protein n=2 Tax=Synechococcus RepID=Q2JPZ0_S...   167   2e-40
UniRef50_A3M1D0 Cyclic 3'5'-adenosine monophosphate phosphodiest...   166   6e-40
UniRef50_Q0EZ19 Ser/Thr protein phosphatase n=1 Tax=Mariprofundu...   166   8e-40
UniRef50_B7S0L2 Calcineurin-like phosphoesterase C-terminal doma...   162   9e-39
UniRef50_Q2KTW6 cAMP phosphodiesterase n=5 Tax=Bordetella RepID=...   160   4e-38
UniRef50_A0Z341 Metallophosphoesterase n=1 Tax=marine gamma prot...   156   6e-37
UniRef50_Q3JEM1 Metallophosphoesterase n=2 Tax=Nitrosococcus oce...   154   3e-36
UniRef50_A8ZM80 Phosphodiesterase, putative n=1 Tax=Acaryochlori...   152   1e-35
UniRef50_B1XQ99 Putative 3',5'-cyclic-nucleotide phosphodiestera...   149   8e-35
UniRef50_Q0AC05 Metallophosphoesterase n=1 Tax=Alkalilimnicola e...   148   2e-34
UniRef50_C8PWU2 Calcineurin phosphoesterase domain protein n=1 T...   145   2e-33
UniRef50_B9ZKN4 Calcineurin phosphoesterase domain protein n=1 T...   144   3e-33
UniRef50_B5JTJ8 Metallophosphoesterase n=1 Tax=gamma proteobacte...   137   3e-31
UniRef50_Q1Q887 Metallophosphoesterase n=2 Tax=Psychrobacter Rep...   134   3e-30
UniRef50_Q2BR54 Metallophosphoesterase n=1 Tax=Neptuniibacter ca...   126   1e-27
UniRef50_A5WBU9 Calcineurin phosphoesterase C-terminal domain pr...   125   1e-27
UniRef50_Q1QUF7 Metallophosphoesterase n=1 Tax=Chromohalobacter ...   122   1e-26
UniRef50_Q7NZT6 3',5'-cyclic-nucleotide phosphodiesterase n=1 Ta...   121   3e-26
UniRef50_D2U008 3',5'-cyclic-nucleotide phosphodiesterase n=1 Ta...   120   5e-26
UniRef50_A1ZTZ2 Metallophosphoesterase n=1 Tax=Microscilla marin...   117   5e-25
UniRef50_Q47WJ3 Cyclic AMP phosphodiesterase n=1 Tax=Colwellia p...   114   2e-24
UniRef50_A7BW21 Cyclic AMP phosphodiesterase n=1 Tax=Beggiatoa s...   113   7e-24
UniRef50_B3Q6B8 Metallophosphoesterase n=8 Tax=Bradyrhizobiaceae...   110   4e-23
UniRef50_Q4JN56 Predicted 3',5'-cyclic-nucleotide phosphodiester...   109   8e-23
UniRef50_A4C954 Cyclic 3',5'-adenosine monophosphate phosphodies...   109   1e-22
UniRef50_B4RZD1 3,5-cyclic-nucleotide phosphodiesterase n=2 Tax=...   108   1e-22
UniRef50_B1KBF2 Metallophosphoesterase n=5 Tax=Proteobacteria Re...   108   2e-22
UniRef50_Q3IG69 Cyclic 3',5'-adenosine monophosphate phosphodies...   107   6e-22
UniRef50_B3TB35 Putative calcineurin-like phosphoesterase n=1 Ta...   105   1e-21
UniRef50_B3YLU1 Cyclic 3',5'-adenosine monophosphate phosphodies...   105   1e-21
UniRef50_Q1LDS0 Metallophosphoesterase n=10 Tax=Proteobacteria R...   105   2e-21
UniRef50_C9RR52 Metallophosphoesterase n=1 Tax=Fibrobacter succi...   105   2e-21
UniRef50_A6D2K7 Ser/Thr protein phosphatase family protein n=1 T...   104   3e-21
UniRef50_A2C6L9 Serine/threonine specific protein phosphatase n=...   104   4e-21
UniRef50_A3RQT5 Icc protein n=4 Tax=Ralstonia solanacearum RepID...   102   1e-20
UniRef50_A7IH99 Metallophosphoesterase n=2 Tax=Xanthobacteraceae...   102   2e-20
UniRef50_Q162P5 Ser/Thr protein phosphatase family protein, puta...   100   4e-20
UniRef50_P05675 Uncharacterized protein syc0937_d n=2 Tax=Synech...    99   1e-19
UniRef50_Q3AIR5 Possible ICC (3',5'-cyclic-nucleotide phosphodie...    99   1e-19
UniRef50_Q15YS5 Metallophosphoesterase n=1 Tax=Pseudoalteromonas...    98   4e-19
UniRef50_B8J1S2 Metallophosphoesterase n=1 Tax=Desulfovibrio des...    96   1e-18
UniRef50_B6IT97 Phosphodiesterase, putative n=1 Tax=Rhodospirill...    94   5e-18
UniRef50_B6J9P9 3',5'-cyclic-nucleotide phosphodiesterase n=7 Ta...    94   7e-18
UniRef50_A9WNR5 Putative 3',5'-cyclic-nucleotide phosphodiestera...    93   9e-18
UniRef50_D1A354 Metallophosphoesterase n=1 Tax=Thermomonospora c...    93   1e-17
UniRef50_A5CN72 Putative 3',5'-cyclic-nucleotide phosphodiestera...    91   3e-17
UniRef50_B9QUB7 Ser/Thr protein phosphatase family protein n=1 T...    91   3e-17
UniRef50_D1U8L8 Metallophosphoesterase n=1 Tax=Desulfovibrio aes...    91   3e-17
UniRef50_Q4ZTD8 Metallophosphoesterase n=4 Tax=Pseudomonas syrin...    91   5e-17
UniRef50_A4F6Q6 Cyclic nucleotide phosphodiesterase n=7 Tax=Acti...    90   6e-17
UniRef50_Q2KTP2 Putative phosphohydrolase n=1 Tax=Bordetella avi...    90   1e-16
UniRef50_A5GLK1 Predicted phosphohydrolase n=4 Tax=Synechococcus...    90   1e-16
UniRef50_C1CX57 Putative Metallophosphoesterase; putative cAMP p...    89   1e-16
UniRef50_C6DHP5 Metallophosphoesterase n=5 Tax=Proteobacteria Re...    88   3e-16
UniRef50_Q1GM28 Metallophosphoesterase n=3 Tax=Rhodobacteraceae ...    88   3e-16
UniRef50_B1A0M0 Ser/Thr protein phosphatase family protein n=3 T...    87   5e-16
UniRef50_Q5Z214 Putative phosphodiesterase n=1 Tax=Nocardia farc...    86   1e-15
UniRef50_A0NY27 Metallophosphoesterase n=2 Tax=Rhodobacteraceae ...    86   1e-15
UniRef50_A6W423 Metallophosphoesterase n=1 Tax=Kineococcus radio...    86   1e-15
UniRef50_Q89MQ1 Bll4141 protein n=1 Tax=Bradyrhizobium japonicum...    86   2e-15
UniRef50_Q0FF25 Putative uncharacterized protein n=1 Tax=Rhodoba...    85   2e-15
UniRef50_D2PQZ3 Metallophosphoesterase n=1 Tax=Kribbella flavida...    85   3e-15
UniRef50_C8SU16 Metallophosphoesterase n=1 Tax=Mesorhizobium opp...    85   3e-15
UniRef50_Q1GWA3 Metallophosphoesterase n=1 Tax=Sphingopyxis alas...    85   3e-15
UniRef50_Q1MS94 Phosphodiesterase n=1 Tax=Lawsonia intracellular...    84   4e-15
UniRef50_B0UF90 Metallophosphoesterase n=2 Tax=Methylobacterium ...    84   5e-15
UniRef50_D2PMS5 Metallophosphoesterase n=1 Tax=Kribbella flavida...    84   6e-15
UniRef50_A1AWV4 Metallophosphoesterase n=5 Tax=Bacteria RepID=A1...    84   6e-15
UniRef50_C5T0E1 Metallophosphoesterase n=1 Tax=Acidovorax delafi...    83   1e-14
UniRef50_C6WAT1 Metallophosphoesterase n=1 Tax=Actinosynnema mir...    82   2e-14
UniRef50_D2AYX4 Metallophosphoesterase n=10 Tax=Actinomycetales ...    81   3e-14
UniRef50_D1XS68 Metallophosphoesterase n=1 Tax=Streptomyces sp. ...    81   5e-14
UniRef50_B6WYD4 Putative uncharacterized protein n=1 Tax=Desulfo...    80   7e-14
UniRef50_Q2J3S6 Metallophosphoesterase n=5 Tax=Rhodopseudomonas ...    80   7e-14
UniRef50_B5J8T8 Ser/Thr protein phosphatase family protein n=2 T...    80   1e-13
UniRef50_B0P519 Putative uncharacterized protein n=2 Tax=Clostri...    80   1e-13
UniRef50_C7S9W5 Protein icc n=17 Tax=Bacteria RepID=C7S9W5_ECOLX       79   1e-13
UniRef50_C1AX97 3',5'-cyclic-nucleotide phosphodiesterase n=24 T...    79   1e-13
UniRef50_A0NQD3 Ser/Thr protein phosphatase family protein n=1 T...    79   2e-13
UniRef50_Q3JU10 Ser/Thr protein phosphatase family protein n=72 ...    79   2e-13
UniRef50_UPI0001B53F99 metallophosphoesterase n=1 Tax=Streptomyc...    78   4e-13
UniRef50_A8U260 Ser/Thr protein phosphatase family protein n=1 T...    77   5e-13
UniRef50_C6A0T0 Predicted phosphohydrolase n=6 Tax=Thermococcus ...    77   6e-13
UniRef50_C6CXY6 Metallophosphoesterase n=1 Tax=Paenibacillus sp....    77   8e-13
UniRef50_Q2RNL1 Metallophosphoesterase n=1 Tax=Rhodospirillum ru...    77   9e-13
UniRef50_D2QL03 Metallophosphoesterase n=1 Tax=Spirosoma lingual...    76   1e-12
UniRef50_Q0RKV8 Putative uncharacterized protein n=1 Tax=Frankia...    76   2e-12
UniRef50_Q6ACA7 Putative uncharacterized protein n=1 Tax=Leifson...    75   2e-12
UniRef50_A5V3T9 Metallophosphoesterase n=2 Tax=Sphingomonadaceae...    75   2e-12
UniRef50_A4AIJ2 Putative uncharacterized protein n=1 Tax=marine ...    75   2e-12
UniRef50_B5JAZ3 Ser/Thr protein phosphatase family protein n=2 T...    75   2e-12
UniRef50_Q20ZN1 Metallophosphoesterase n=1 Tax=Rhodopseudomonas ...    75   3e-12
UniRef50_C7MAF7 Predicted phosphohydrolase n=1 Tax=Brachybacteri...    75   3e-12
UniRef50_A9CKB5 Putative uncharacterized protein n=2 Tax=Alphapr...    75   3e-12
UniRef50_A5FYX3 Metallophosphoesterase n=1 Tax=Acidiphilium cryp...    74   4e-12
UniRef50_Q2J948 Metallophosphoesterase n=5 Tax=Actinomycetales R...    74   5e-12
UniRef50_B6R8M8 Ser/Thr protein phosphatase family protein n=1 T...    74   5e-12
UniRef50_D2EUB1 Metallophosphoesterase n=1 Tax=Bacteroides sp. D...    73   1e-11
UniRef50_B7QYI4 3',5'-cyclic-nucleotide phosphodiesterase, CpdA ...    73   1e-11
UniRef50_Q9V2G8 Predicted phosphohydrolase, putative n=3 Tax=Pyr...    72   1e-11
UniRef50_A4EV76 3',5'-cyclic-nucleotide phosphodiesterase, cpdA ...    72   2e-11
UniRef50_Q982B7 Mll9148 protein n=1 Tax=Mesorhizobium loti RepID...    71   3e-11
UniRef50_C6VLV6 3',5'-cyclic-nucleotide phosphodiesterase n=3 Ta...    71   4e-11
UniRef50_A3W656 Ser/Thr protein phosphatase family protein n=3 T...    70   5e-11
UniRef50_Q28NL1 Metallophosphoesterase n=2 Tax=Rhodobacteraceae ...    70   6e-11
UniRef50_A3WHQ7 Putative cAMP phosphodiesterase n=1 Tax=Erythrob...    70   8e-11
UniRef50_Q8TVF8 Predicted calcineurin superfamily phosphohydrola...    70   9e-11
UniRef50_C6BIA6 Metallophosphoesterase n=2 Tax=Ralstonia pickett...    69   1e-10
UniRef50_C6B6U2 Metallophosphoesterase n=2 Tax=Rhizobium legumin...    69   2e-10
UniRef50_C7D8R5 Phosphodiesterase n=1 Tax=Thalassiobium sp. R2A6...    69   2e-10
UniRef50_A9DXP9 Putative uncharacterized protein n=1 Tax=Oceanib...    68   3e-10
UniRef50_A6U5M4 Metallophosphoesterase n=3 Tax=Rhizobiaceae RepI...    67   5e-10
UniRef50_A5FX65 Metallophosphoesterase n=1 Tax=Acidiphilium cryp...    67   6e-10
UniRef50_C5CDX7 Metallophosphoesterase n=1 Tax=Kosmotoga olearia...    66   1e-09
UniRef50_A3K5W8 Phosphodiesterase n=1 Tax=Sagittula stellata E-3...    66   1e-09
UniRef50_C9CTH4 Phosphodiesterase n=6 Tax=Proteobacteria RepID=C...    66   1e-09
UniRef50_B7BFD3 Putative uncharacterized protein n=1 Tax=Parabac...    66   1e-09
UniRef50_B3Q702 Metallophosphoesterase n=5 Tax=Alphaproteobacter...    66   1e-09
UniRef50_A9FYQ8 Phosphodiesterase n=6 Tax=Rhodobacteraceae RepID...    65   2e-09
UniRef50_C5EL28 Predicted protein n=1 Tax=Clostridiales bacteriu...    65   2e-09
UniRef50_C9AD97 Phosphoesterase n=3 Tax=Enterococcus casseliflav...    65   2e-09
UniRef50_A9CI50 Putative uncharacterized protein n=1 Tax=Agrobac...    65   3e-09
UniRef50_B5K790 Metallophosphoesterase n=1 Tax=Octadecabacter an...    64   8e-09
UniRef50_D0L6V7 Metallophosphoesterase n=1 Tax=Gordonia bronchia...    63   9e-09
UniRef50_A3JT02 Putative uncharacterized protein n=1 Tax=Rhodoba...    62   1e-08
UniRef50_B9XC60 Metallophosphoesterase n=1 Tax=bacterium Ellin51...    62   1e-08
UniRef50_C6VU97 Metallophosphoesterase n=1 Tax=Dyadobacter ferme...    61   3e-08
UniRef50_A1ZMS0 Putative uncharacterized protein n=1 Tax=Microsc...    61   4e-08
UniRef50_C6D6T3 Metallophosphoesterase n=1 Tax=Paenibacillus sp....    61   5e-08
UniRef50_A4EJU5 3',5'-cyclic-nucleotide phosphodiesterase, cpdA ...    61   5e-08
UniRef50_C8QH10 Metallophosphoesterase n=3 Tax=Enterobacteriacea...    60   5e-08
UniRef50_A3U194 Putative uncharacterized protein n=1 Tax=Oceanic...    60   6e-08
UniRef50_B5YAA1 Membrane-associated protein, putative n=2 Tax=Di...    60   6e-08
UniRef50_A1SEE2 Metallophosphoesterase n=2 Tax=Actinobacteria (c...    60   6e-08
UniRef50_B4D428 Metallophosphoesterase n=1 Tax=Chthoniobacter fl...    60   8e-08
UniRef50_O27755 Transcriptional regulator Icc related protein n=...    60   8e-08
UniRef50_A5UK60 Predicted phosphohydrolase, calcineurin-like sup...    59   1e-07
UniRef50_A6CD50 Cyclic 3',5'-adenosine monophosphate phosphodies...    59   2e-07
UniRef50_B1LAV7 Metallophosphoesterase n=2 Tax=Thermotoga sp. RQ...    59   2e-07
UniRef50_C7NWB5 Metallophosphoesterase n=1 Tax=Halomicrobium muk...    58   3e-07
UniRef50_B9TAV3 Putative uncharacterized protein n=1 Tax=Ricinus...    57   6e-07
UniRef50_A6WWL5 Metallophosphoesterase n=1 Tax=Ochrobactrum anth...    57   6e-07
UniRef50_C0WNK1 3',5'-cyclic-nucleotide phosphodiesterase n=3 Ta...    57   8e-07
UniRef50_O66909 Putative uncharacterized protein n=1 Tax=Aquifex...    56   1e-06
UniRef50_C2KF95 Serine/threonine protein phosphatase family prot...    56   1e-06
UniRef50_C7Q3U3 Metallophosphoesterase n=3 Tax=Actinomycetales R...    56   2e-06
UniRef50_A1HNK3 Metallophosphoesterase n=1 Tax=Thermosinus carbo...    56   2e-06
UniRef50_A6DDC8 Metallophosphoesterase n=1 Tax=Caminibacter medi...    55   2e-06
UniRef50_A9DF72 Possible 3',5'-cyclic-nucleotide phosphodiestera...    55   3e-06
UniRef50_A9A2N5 Metallophosphoesterase n=4 Tax=marine archaeal g...    54   4e-06
UniRef50_C2E1N9 Serine/threonine protein phosphatase family prot...    54   6e-06
UniRef50_D1B7Z2 Metallophosphoesterase n=1 Tax=Thermanaerovibrio...    54   6e-06
UniRef50_Q2JP63 Ser/Thr protein phosphatase family protein n=2 T...    54   6e-06
UniRef50_C8XD18 Metallophosphoesterase n=1 Tax=Nakamurella multi...    54   7e-06
UniRef50_Q1AXD2 Metallophosphoesterase n=1 Tax=Rubrobacter xylan...    54   8e-06
UniRef50_Q46D43 3,5-cyclic-nucleotide phosphodiesterase n=8 Tax=...    53   1e-05
UniRef50_B9K806 Metallophosphoesterase n=1 Tax=Thermotoga neapol...    52   2e-05
UniRef50_A1DIP8 Ser/Thr protein phosphatase family protein n=1 T...    52   2e-05
UniRef50_D2QD99 Metallophosphoesterase n=1 Tax=Spirosoma lingual...    52   2e-05
UniRef50_C7PKP5 Metallophosphoesterase n=1 Tax=Chitinophaga pine...    52   3e-05
UniRef50_UPI000185BF3C putative secreted protein n=1 Tax=Coryneb...    51   3e-05
UniRef50_O30241 LacZ expression regulatory protein (Icc) n=1 Tax...    50   7e-05
UniRef50_D1N465 Metallophosphoesterase n=1 Tax=Victivallis vaden...    50   7e-05
UniRef50_A6E4I6 Putative uncharacterized protein n=1 Tax=Roseova...    50   8e-05
UniRef50_Q1AVF9 Metallophosphoesterase n=1 Tax=Rubrobacter xylan...    50   9e-05
UniRef50_Q9YDE7 Putative uncharacterized protein n=1 Tax=Aeropyr...    50   9e-05
UniRef50_C2FYP3 Metallophosphoesterase n=1 Tax=Sphingobacterium ...    50   1e-04
UniRef50_C7D3F7 Predicted protein n=5 Tax=Enterococcus RepID=C7D...    49   2e-04
UniRef50_C5AJE8 Metallophosphoesterase n=1 Tax=Burkholderia glum...    49   2e-04
UniRef50_B8MX07 Putative uncharacterized protein n=1 Tax=Aspergi...    48   3e-04
UniRef50_D0MIH6 Metallophosphoesterase n=1 Tax=Rhodothermus mari...    48   4e-04
UniRef50_C8S8V3 Metallophosphoesterase n=1 Tax=Ferroglobus placi...    48   4e-04
UniRef50_Q255X1 Phosphohydrolase n=13 Tax=Chlamydiaceae RepID=Q2...    48   4e-04
UniRef50_Q28TG5 Metallophosphoesterase n=1 Tax=Jannaschia sp. CC...    48   4e-04
UniRef50_A3WFW5 Putative uncharacterized protein n=1 Tax=Erythro...    47   5e-04
UniRef50_Q3Y3L7 Metallophosphoesterase n=1 Tax=Enterococcus faec...    47   6e-04
UniRef50_Q1NCC3 Putative uncharacterized protein n=1 Tax=Sphingo...    47   6e-04
UniRef50_Q2SWK2 Ser/Thr protein phosphatase family protein n=37 ...    47   7e-04
UniRef50_Q03AS7 Predicted phosphohydrolase n=9 Tax=Lactobacillus...    47   7e-04
UniRef50_C1VB71 Predicted phosphohydrolase n=1 Tax=Halogeometric...    47   8e-04
UniRef50_B2TAN8 Metallophosphoesterase n=1 Tax=Burkholderia phyt...    47   9e-04
UniRef50_A6WZI2 Metallophosphoesterase n=49 Tax=Proteobacteria R...    47   0.001
UniRef50_C5PKR3 Putative uncharacterized protein n=2 Tax=Sphingo...    47   0.001
UniRef50_B5ISV8 Ser/Thr protein phosphatase family protein n=1 T...    47   0.001
UniRef50_A0RA77 Purple acid phosphatase/fibronectin domain prote...    46   0.001
UniRef50_Q7NJG1 Glr1871 protein n=1 Tax=Gloeobacter violaceus Re...    46   0.001
UniRef50_A4WK20 Metallophosphoesterase n=5 Tax=Thermoproteaceae ...    46   0.001
UniRef50_UPI0001BC808F hypothetical protein BacD2_17610 n=1 Tax=...    46   0.002
UniRef50_B5JMC7 Ser/Thr protein phosphatase family protein n=1 T...    45   0.002
UniRef50_B1ZFT6 Metallophosphoesterase n=1 Tax=Methylobacterium ...    45   0.002
UniRef50_C6W404 Metallophosphoesterase n=1 Tax=Dyadobacter ferme...    45   0.003
UniRef50_A1WSG8 Putative cAMP phosphodiesterase n=1 Tax=Verminep...    45   0.003
UniRef50_C6XUF6 Metallophosphoesterase n=1 Tax=Pedobacter hepari...    45   0.003
UniRef50_B5HU26 Integral membrane protein n=17 Tax=Streptomyces ...    45   0.003
UniRef50_C8QWM6 Metallophosphoesterase n=1 Tax=Desulfurivibrio a...    45   0.003
UniRef50_B3EHZ5 Metallophosphoesterase n=1 Tax=Chlorobium limico...    45   0.003
UniRef50_A9B0W4 Metallophosphoesterase n=1 Tax=Herpetosiphon aur...    45   0.004
UniRef50_B1ZLW2 Metallophosphoesterase n=6 Tax=Alphaproteobacter...    44   0.004
UniRef50_D2QP98 Metallophosphoesterase n=1 Tax=Spirosoma lingual...    44   0.005
UniRef50_A1S175 Metallophosphoesterase n=1 Tax=Thermofilum pende...    44   0.005
UniRef50_A6DHY4 Putative uncharacterized protein n=1 Tax=Lentisp...    44   0.006
UniRef50_D1X994 Metallophosphoesterase n=1 Tax=Streptomyces sp. ...    44   0.006
UniRef50_Q89N60 Bll3982 protein n=1 Tax=Bradyrhizobium japonicum...    44   0.007
UniRef50_Q01N63 Metallophosphoesterase n=1 Tax=Candidatus Soliba...    44   0.007
UniRef50_A6Q7J3 Putative uncharacterized protein n=2 Tax=unclass...    44   0.007
UniRef50_B9TNQ0 Putative uncharacterized protein (Fragment) n=1 ...    44   0.008
UniRef50_Q64Z92 Serine/threonine protein kinase related protein ...    44   0.008
UniRef50_A6G589 Putative uncharacterized protein n=1 Tax=Plesioc...    44   0.008
UniRef50_A4A1K6 Ser/Thr protein phosphatase family protein (Frag...    44   0.008
UniRef50_B1R0V9 Ser/Thr protein phosphatase family protein n=3 T...    43   0.010
UniRef50_C0EE22 Putative uncharacterized protein n=1 Tax=Clostri...    43   0.011
UniRef50_UPI000169559C enhancin family protein n=3 Tax=Paenibaci...    43   0.011
UniRef50_UPI0001745388 Ser/Thr protein phosphatase family protei...    43   0.012
UniRef50_Q2SPP8 Predicted phosphohydrolase n=1 Tax=Hahella cheju...    43   0.012
UniRef50_Q6LRK7 Putative uncharacterized protein n=2 Tax=Photoba...    43   0.013
UniRef50_Q03NU9 Predicted phosphohydrolase n=1 Tax=Lactobacillus...    43   0.013
UniRef50_Q1DCU4 Ser/Thr protein phosphatase family protein n=2 T...    43   0.015
UniRef50_D2PXP9 Metallophosphoesterase n=1 Tax=Kribbella flavida...    43   0.015
UniRef50_C5SJD5 Metallophosphoesterase n=1 Tax=Asticcacaulis exc...    42   0.016

>UniRef50_P0AEW5 Protein icc n=161 Tax=Gammaproteobacteria RepID=ICC_ECO57
          Length = 275

 Score =  565 bits (1455), Expect = e-160,   Method: Compositional matrix adjust.
 Identities = 275/275 (100%), Positives = 275/275 (100%)

Query: 1   MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV 60
           MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
Sbjct: 1   MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV 60

Query: 61  ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE 120
           ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
Sbjct: 61  ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE 120

Query: 121 QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL 180
           QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
Sbjct: 121 QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL 180

Query: 181 RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA 240
           RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
Sbjct: 181 RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA 240

Query: 241 PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY 275
           PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
Sbjct: 241 PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY 275


>UniRef50_P44685 Protein icc homolog n=27 Tax=Pasteurellaceae RepID=ICC_HAEIN
          Length = 274

 Score =  304 bits (779), Expect = 2e-81,   Method: Compositional matrix adjust.
 Identities = 140/266 (52%), Positives = 186/266 (69%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
           A +  +++LQITD HLF  +   LLGVNT  S+  VL+ I+   +EFD+I+ATGDL QD 
Sbjct: 9   AEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNEFDVILATGDLVQDS 68

Query: 70  SSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDS 129
           S   Y  F E +  F  P  W+PGNHDFQP M   L    ++ AK + +GE WQ LLLDS
Sbjct: 69  SDEGYIRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGEHWQALLLDS 128

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
           QV+GVPHG+LS+ QL+ L+  L   PER+TL++LHHH LP   +WLDQH+LRN+ EL  V
Sbjct: 129 QVYGVPHGQLSQHQLDLLKETLGKNPERYTLVVLHHHLLPTNSAWLDQHNLRNSHELAEV 188

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELH 249
           LA F +VK +L GHIHQE++ +WNG +++ATP+TC+QFKP C  F+LDT+ PGWR +ELH
Sbjct: 189 LAPFTNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQPGWREIELH 248

Query: 250 ADGTLTTEVHRLADTRFQPDTASEGY 275
           +DG++ TEV R+    F P+   EGY
Sbjct: 249 SDGSIRTEVKRIQQAEFFPNMQEEGY 274


>UniRef50_D2U2B8 Cyclic 3',5'-adenosine monophosphate phosphodiesterase n=4
           Tax=Gammaproteobacteria RepID=D2U2B8_9ENTR
          Length = 265

 Score =  303 bits (775), Expect = 6e-81,   Method: Compositional matrix adjust.
 Identities = 154/265 (58%), Positives = 192/265 (72%), Gaps = 4/265 (1%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +RILQITDTHLFA   + LLGVNT+ S+ AV++AI       DL+VATGDLAQDQS+ AY
Sbjct: 1   MRILQITDTHLFANADDTLLGVNTFASFHAVIDAILVRNENVDLVVATGDLAQDQSAQAY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
           QHFAEGI    APCVWLPGNHD+QPAM + L  AGI P+K++ I + WQIL+LDSQ+ G 
Sbjct: 61  QHFAEGIKRLSAPCVWLPGNHDYQPAMVATLAKAGILPSKQLLINDNWQILMLDSQIQGA 120

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
            HG+LS+ QL W++       ER  LL+LHHHPLP+GC+WLDQH LRN+  L   L ++ 
Sbjct: 121 VHGKLSKQQLLWMKSCFDAYTERSHLLMLHHHPLPSGCTWLDQHRLRNSHILADYLKQYQ 180

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELH----A 250
            +K +LCGHIHQE+D  W G R++ATPSTC+QFKPHC+NFTLDT+ PGWR L+L      
Sbjct: 181 KIKAILCGHIHQEIDEYWQGVRMMATPSTCIQFKPHCTNFTLDTMTPGWRYLDLSINDAG 240

Query: 251 DGTLTTEVHRLADTRFQPDTASEGY 275
           +  L T+V RL   +F PD  S GY
Sbjct: 241 EDVLNTQVCRLDSDKFCPDLDSGGY 265


>UniRef50_C6AKV1 Icc n=6 Tax=Pasteurellaceae RepID=C6AKV1_AGGAN
          Length = 274

 Score =  294 bits (752), Expect = 3e-78,   Method: Compositional matrix adjust.
 Identities = 135/260 (51%), Positives = 181/260 (69%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           RI+QITD HLF   +  LLG+NT  S+  VL  I+  Q+ +DL++ATGDL QD S   Y 
Sbjct: 15  RIVQITDPHLFKDTNGELLGINTQASFSQVLTEIQQQQYAYDLVLATGDLVQDSSDEGYL 74

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVP 135
           HF E + +      W+PGNHDFQP M+  L    IS  K + +G++WQILLLDSQ+ GVP
Sbjct: 75  HFCESVKALEKMVFWIPGNHDFQPKMFDLLTTDNISAKKHILLGDRWQILLLDSQISGVP 134

Query: 136 HGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPH 195
           HG+LSE+QL+WL  KL + P+R++L++LHHH L    +WLDQH+LRNA EL  +LA F +
Sbjct: 135 HGQLSEYQLDWLLAKLKEYPQRYSLVVLHHHILSTHSAWLDQHNLRNAHELAYILAPFSN 194

Query: 196 VKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLT 255
           VK +L GHIHQ++D +W+G +++ATPST +QFKP  + F LDT+ PGWR +ELHADG + 
Sbjct: 195 VKGILHGHIHQQVDGEWHGYKVMATPSTGIQFKPDSNTFALDTVQPGWREIELHADGHIE 254

Query: 256 TEVHRLADTRFQPDTASEGY 275
           T V R+    F P+   EGY
Sbjct: 255 TRVKRIQHKTFLPNLQEEGY 274


>UniRef50_C4L9C4 Calcineurin phosphoesterase domain protein n=3
           Tax=Gammaproteobacteria RepID=C4L9C4_TOLAT
          Length = 273

 Score =  283 bits (725), Expect = 3e-75,   Method: Compositional matrix adjust.
 Identities = 137/270 (50%), Positives = 186/270 (68%), Gaps = 1/270 (0%)

Query: 6   TLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDL 65
           TL    +  VR+LQI+DTHLFA+ +  LLG+ T +S+QAVL+AI      +D+++ATGDL
Sbjct: 5   TLSKPDDGIVRLLQISDTHLFAETNRDLLGIATADSFQAVLDAITELPQTYDVVLATGDL 64

Query: 66  AQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQIL 125
           +QD S+A+YQ FA  + + + P  WLPGNHD +  M + LQ +GI P  ++ +G+ WQ++
Sbjct: 65  SQDHSAASYQRFARMVTTLQKPVHWLPGNHDHRVLMQNELQVSGIRPEMQL-VGDHWQVI 123

Query: 126 LLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGE 185
           LLDSQV+G PHG LS  QLE LE  L   PE+H L+ LHHH  P G  WLDQH L+NA +
Sbjct: 124 LLDSQVYGTPHGWLSHLQLEQLEAALLQYPEKHVLICLHHHTFPIGSIWLDQHDLKNASD 183

Query: 186 LDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRT 245
              VLA++P VK +LCGH+HQE D    G R L +PSTC+QF+P   +F+LDT++PGWR 
Sbjct: 184 FLAVLARYPRVKAVLCGHVHQEYDQYHQGIRFLTSPSTCIQFQPLSVDFSLDTMSPGWRY 243

Query: 246 LELHADGTLTTEVHRLADTRFQPDTASEGY 275
           L+L+ DG + T+V RL   +F PD  S GY
Sbjct: 244 LQLYPDGRIATQVWRLEPGQFAPDLQSTGY 273


>UniRef50_Q7MNX9 Cyclic AMP phosphodiesterase n=60 Tax=Gammaproteobacteria
           RepID=Q7MNX9_VIBVY
          Length = 274

 Score =  278 bits (712), Expect = 1e-73,   Method: Compositional matrix adjust.
 Identities = 138/265 (52%), Positives = 188/265 (70%)

Query: 11  GEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQS 70
            E  +++LQITDTHLFA    +LL V T +S+QAV+E +     EFD ++ATGD++QD S
Sbjct: 10  SENSIKLLQITDTHLFASDEGSLLSVKTLQSFQAVVEQVMARHVEFDYLLATGDISQDHS 69

Query: 71  SAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQ 130
           +A+YQ FA+GIA     C WLPGNHD++P M S L    I+  ++V +   WQ++LLDSQ
Sbjct: 70  AASYQRFADGIAPLEKACFWLPGNHDYKPNMSSVLPSPQITTPEQVELNAHWQLILLDSQ 129

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
           V GVPHG LS+ QL  LE  L  +PE++TL+LLHHHPL  G +WLDQH+L++A     ++
Sbjct: 130 VVGVPHGRLSDQQLSMLEHHLQASPEKNTLILLHHHPLLVGSAWLDQHTLKDAEAFWQIV 189

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHA 250
            +FP VK ++CGH+HQ++++   G R++ATPSTCVQFKP   +F LDT++PGWR L LHA
Sbjct: 190 ERFPMVKGIVCGHVHQDMNVMHKGIRVMATPSTCVQFKPQSDDFALDTVSPGWRELTLHA 249

Query: 251 DGTLTTEVHRLADTRFQPDTASEGY 275
           +G +TT+V RLA   F PD  S GY
Sbjct: 250 NGEITTQVQRLASGSFLPDFTSSGY 274


>UniRef50_A6F721 Icc protein-like protein n=1 Tax=Moritella sp. PE36
           RepID=A6F721_9GAMM
          Length = 274

 Score =  262 bits (670), Expect = 8e-69,   Method: Compositional matrix adjust.
 Identities = 129/261 (49%), Positives = 177/261 (67%), Gaps = 1/261 (0%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + +LQ+TDTHLFA   + LLGV T  SY+ V++AI  +Q  FD ++ATGD++QD + A+Y
Sbjct: 15  INLLQVTDTHLFATAEKDLLGVKTQLSYRHVIDAILQNQQPFDAVLATGDISQDNTPASY 74

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
           Q+FA+ I     PC WLPGNHD  P M  AL+  G+   K   +G+ WQI+LLDSQ+ G 
Sbjct: 75  QYFAQHIKRLNKPCYWLPGNHDNIPLMADALRAEGVLADKYKVVGD-WQIVLLDSQLTGS 133

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
           P G L+  QL  L+ +L+  P++  L++LHH+  P GC WLDQH LRNA     +LAK P
Sbjct: 134 PAGYLAPEQLLLLDEQLSAHPDKFALVVLHHNVYPVGCKWLDQHLLRNADAFLAILAKHP 193

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTL 254
              ++L GH+HQ+LD  + G   +A+PSTC QFKPHC  FTLD  APGWR L+LH+DG++
Sbjct: 194 QANHVLFGHVHQQLDKTYAGIHFMASPSTCFQFKPHCDEFTLDARAPGWRYLQLHSDGSI 253

Query: 255 TTEVHRLADTRFQPDTASEGY 275
            ++V RL++  F PD  S+GY
Sbjct: 254 NSQVWRLSNNDFNPDLESKGY 274


>UniRef50_A1SZX9 Cyclic AMP phosphodiesterase n=2 Tax=Psychromonas
           RepID=A1SZX9_PSYIN
          Length = 278

 Score =  246 bits (628), Expect = 6e-64,   Method: Compositional matrix adjust.
 Identities = 113/261 (43%), Positives = 176/261 (67%), Gaps = 1/261 (0%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +++LQITDTHLF+ +++ LLG+   ESY+AV++    +  +   +++TGDL+QD +  +Y
Sbjct: 19  LQLLQITDTHLFSDRNKDLLGIKPAESYEAVIKHASRYSSKCQAVLSTGDLSQDHTQQSY 78

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
             F + I +   PC WLPGNHD Q  M  +L   G++ +K++ + + WQI+LLDSQV G 
Sbjct: 79  LDFTKQIKTLNLPCYWLPGNHDTQSVMLPSLLQEGLAQSKQI-VSDFWQIILLDSQVEGA 137

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
           PHG L+E QL +L++ L + P++HTL+ +HHH LP   +WLDQH L+N  +   ++    
Sbjct: 138 PHGFLTEQQLNFLQQALTEYPDKHTLICVHHHVLPVKSAWLDQHILKNNQQFLELIKLHK 197

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTL 254
           +V+ +L GH+HQ  D+++N  R L +PSTC+QFKP+  +F +D  APG+R L LH +GT+
Sbjct: 198 NVRVVLSGHVHQAGDIEFNQVRFLTSPSTCLQFKPNSEDFDVDDSAPGYRYLALHKNGTI 257

Query: 255 TTEVHRLADTRFQPDTASEGY 275
           TT+V R+A   F P+  + GY
Sbjct: 258 TTKVERVAHGEFSPNKNATGY 278


>UniRef50_Q12J78 Metallophosphoesterase n=21 Tax=Shewanella RepID=Q12J78_SHEDO
          Length = 279

 Score =  230 bits (587), Expect = 3e-59,   Method: Compositional matrix adjust.
 Identities = 116/265 (43%), Positives = 167/265 (63%), Gaps = 5/265 (1%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           VR++Q+TD HLFA     LLGV T++S+ AVL  I    H   L++ATGDL+QD S  +Y
Sbjct: 16  VRLVQVTDPHLFADLEAQLLGVTTYQSFSAVLAMINQANHGQHLLLATGDLSQDYSPESY 75

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
           Q FA  +     PC +LPGNHD    M  ++Q   +   +R+ IG QWQIL+L+S + G 
Sbjct: 76  QLFANTVKRVPVPCHYLPGNHDDARLMNLSVQGDHVFGQQRIIIG-QWQILMLNSTLIGK 134

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
           P G L+  Q   +++ +A AP++H LL +HH+P+   C+WLDQH + N  EL     +F 
Sbjct: 135 PGGYLAPSQFTLIKQAIAQAPDKHVLLAMHHNPVLVDCAWLDQHCMANGEELIDFAGQFK 194

Query: 195 HVKYLLCGHIHQELDLDWNGR----RLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHA 250
            +K L+ GH+HQ LD    G+    +L+ATPSTC+QFKP  ++F LD + PG+R L+L +
Sbjct: 195 QIKGLVWGHVHQALDRQVLGQFGPIKLMATPSTCIQFKPKSAHFALDGLQPGYRLLDLAS 254

Query: 251 DGTLTTEVHRLADTRFQPDTASEGY 275
           DG++ T+V+RLA   F  D  + GY
Sbjct: 255 DGSIHTQVYRLAGDEFSADNHANGY 279


>UniRef50_Q2S9N2 Predicted phosphohydrolase n=1 Tax=Hahella chejuensis KCTC 2396
           RepID=Q2S9N2_HAHCH
          Length = 267

 Score =  214 bits (545), Expect = 2e-54,   Method: Compositional matrix adjust.
 Identities = 108/259 (41%), Positives = 158/259 (61%), Gaps = 2/259 (0%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           ++Q+TD+HL  +    LLG+NT  S  AVL  +R +    DL++ATGD+AQD S+ AY+ 
Sbjct: 11  VIQVTDSHLRREPDGTLLGMNTRRSLDAVLSLVRANHENPDLVLATGDIAQDGSTEAYEC 70

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPH 136
           F E +  F+ P  W  GNHD    M  A+QD       ++F    W+++ LDS V    +
Sbjct: 71  FHEKMLPFQCPVYWFSGNHDDPGVMAKAVQDPECLAKVKIF--GPWKLIFLDSSVRRKVY 128

Query: 137 GELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHV 196
           G+L++ +L+ L+ +L     +H ++  HHHP+   C+WLD   L N  E   V+  + HV
Sbjct: 129 GKLAKKELQLLKAELEKDQGKHVIICFHHHPVDVDCAWLDTIGLHNRDEFFAVIDAYDHV 188

Query: 197 KYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTT 256
           + +L GHIHQE D   NG RLLATPSTCVQFKP+  +F +D +APG+R L+L+ DG + T
Sbjct: 189 RLVLWGHIHQEYDQVRNGVRLLATPSTCVQFKPYSEDFAVDNLAPGYRWLKLYPDGRVDT 248

Query: 257 EVHRLADTRFQPDTASEGY 275
            V R +   F+ D +S+GY
Sbjct: 249 SVVRASHIEFEVDLSSKGY 267


>UniRef50_Q1N2L2 Metallophosphoesterase n=1 Tax=Bermanella marisrubri
           RepID=Q1N2L2_9GAMM
          Length = 260

 Score =  213 bits (541), Expect = 7e-54,   Method: Compositional matrix adjust.
 Identities = 108/261 (41%), Positives = 155/261 (59%), Gaps = 4/261 (1%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           + +QITD+HLF+ K   LLG++T  S  AVLE +R    ++D  + TGDL+QD +  +YQ
Sbjct: 3   KFIQITDSHLFSTKPGKLLGMDTQYSLDAVLEKLRDEHCDYDFYLCTGDLSQDGTVESYQ 62

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYS-ALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
           H    +A    P  W+PGNHD +P M   A ++  + P   VF    WQI++LDSQV G 
Sbjct: 63  HLKNTLAKDGKPQHWIPGNHDHRPNMVQVASEEVEMKP---VFRAGAWQIIMLDSQVPGA 119

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
             G  SE QL+ L   L       TL+ +HHHP+   C WLD   +RN+     ++ ++ 
Sbjct: 120 VGGNFSESQLQLLRDALDADSGSPTLVTMHHHPIAMECDWLDTQQIRNSQAFRDIIDQYD 179

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTL 254
           +VK +L GH+HQ+ D   NG R ++TPSTCVQF P   +F +DT  PG+R +ELH DG++
Sbjct: 180 NVKVVLWGHVHQDSDQLINGVRFISTPSTCVQFTPESEDFDVDTCGPGYRWMELHDDGSI 239

Query: 255 TTEVHRLADTRFQPDTASEGY 275
            T V R+    F+ D + +GY
Sbjct: 240 KTGVSRVEHIDFEIDYSVKGY 260


>UniRef50_A4B8Z0 Putative uncharacterized protein n=1 Tax=Reinekea blandensis MED297
           RepID=A4B8Z0_9GAMM
          Length = 263

 Score =  211 bits (536), Expect = 3e-53,   Method: Compositional matrix adjust.
 Identities = 105/259 (40%), Positives = 156/259 (60%), Gaps = 2/259 (0%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           ++QITD HL A     LLG+NT  S + +++ +     E DL++ATGD+AQD S  AY++
Sbjct: 7   LVQITDPHLHATSDGTLLGMNTENSLRLIVDRVVNEVPEVDLVIATGDIAQDSSVQAYRN 66

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPH 136
           F E I    AP  W+PGNHD +  M +A +D  +  A+ V+    W I+LLDS V G  +
Sbjct: 67  FLELIRPISAPMRWIPGNHDSRENMATAGKD--LQHAEPVYELGDWVIILLDSIVPGRVY 124

Query: 137 GELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHV 196
           G L   QLE L++ L    +RH L+  HHHP+P    W+DQ  +RN      ++  + ++
Sbjct: 125 GNLDPDQLELLQKTLDKYQDRHVLIGFHHHPVPMKSRWIDQIGVRNRESFQALVNHYDNI 184

Query: 197 KYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTT 256
           + ++CGH+HQ+ D   NG R ++TPSTCVQF P   +F +D++ P +RTL LH DG L T
Sbjct: 185 RAVVCGHVHQDSDQVINGIRYISTPSTCVQFLPKSQDFGIDSLGPAYRTLTLHPDGQLDT 244

Query: 257 EVHRLADTRFQPDTASEGY 275
            + R+    F+ D + +GY
Sbjct: 245 TISRIDGVDFEIDYSQKGY 263


>UniRef50_Q4KJ96 Cyclic AMP phosphodiesterase n=25 Tax=Bacteria RepID=Q4KJ96_PSEF5
          Length = 271

 Score =  209 bits (532), Expect = 7e-53,   Method: Compositional matrix adjust.
 Identities = 116/262 (44%), Positives = 158/262 (60%), Gaps = 4/262 (1%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           V ++Q++D+HLFA+    LLG+NT +S Q V++ +   Q   DL++ATGDL+QD +  +Y
Sbjct: 13  VLLVQLSDSHLFAETDGTLLGMNTADSLQRVIDLVLAQQPRIDLMLATGDLSQDGTLESY 72

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGI-SPAKRVFIGEQWQILLLDSQVFG 133
           Q F +      AP  WLPGNHD    M  A   + +  P   V IG  W+I LLDS V G
Sbjct: 73  QRFRQLTRQIAAPGRWLPGNHDEPQVMEQAASGSDLLDPV--VDIG-NWRITLLDSAVPG 129

Query: 134 VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKF 193
              G L + QL+ L R L++APERH L+ LHHHP+   C+W++   LRNA  L  V+  F
Sbjct: 130 SVPGYLQDEQLQLLTRSLSEAPERHHLVCLHHHPVSIDCAWMEPIGLRNAQALFAVIDAF 189

Query: 194 PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGT 253
           P V+ +L GH+HQE+D      RLLA+PSTC+QF+P   +F ++   PG+R L L  DG 
Sbjct: 190 PQVRAVLWGHVHQEIDRLRGDVRLLASPSTCIQFEPLSDDFKVEEQVPGYRWLRLLPDGR 249

Query: 254 LTTEVHRLADTRFQPDTASEGY 275
           L T V R+    F  D  SEGY
Sbjct: 250 LETGVQRVEGYEFTIDYGSEGY 271


>UniRef50_A1TYT4 Calcineurin phosphoesterase C-terminal domain protein n=3
           Tax=Marinobacter RepID=A1TYT4_MARAV
          Length = 268

 Score =  207 bits (528), Expect = 3e-52,   Method: Compositional matrix adjust.
 Identities = 113/261 (43%), Positives = 158/261 (60%), Gaps = 2/261 (0%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + +LQ+TD HL A    ALLGVNT +S  AV+  +  +  + DLI+ATGDL QD S  AY
Sbjct: 10  LNVLQLTDPHLMASADGALLGVNTRDSLAAVIGEVLRNHGQPDLILATGDLTQDASPEAY 69

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
           ++F E + +F  P +W+ GNHD   A+ SA+  A     ++ +I   WQ ++LDS V G 
Sbjct: 70  RYFGEQLQAFDCPSLWIAGNHD-DSALLSAIA-AETGSDQKQWIQGGWQFVMLDSSVHGK 127

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
             GELS  +L +L+R L++ PE   ++ LHHHP+  G  W+++  L+N      V+ + P
Sbjct: 128 VFGELSADELSFLDRALSERPELPAMVCLHHHPVDIGSDWMEKIGLKNRDAFWQVIDRHP 187

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTL 254
            V+ +L GHIHQEL+   NG  LLATPSTC+QF    S+F ++ +APG+R LEL   G  
Sbjct: 188 QVRVVLWGHIHQELEQQRNGACLLATPSTCIQFATGSSDFAVEPLAPGYRWLELDPSGCF 247

Query: 255 TTEVHRLADTRFQPDTASEGY 275
            TEV R A   F  D  S GY
Sbjct: 248 KTEVRRAASFEFDLDEKSTGY 268


>UniRef50_Q0VLK4 Icc protein, putative n=2 Tax=Alcanivorax RepID=Q0VLK4_ALCBS
          Length = 268

 Score =  204 bits (518), Expect = 3e-51,   Method: Compositional matrix adjust.
 Identities = 107/261 (40%), Positives = 150/261 (57%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +R++Q++D HLFA     LLG+NT  S   VLE IR  Q   DLI+ATGDL+QD S  +Y
Sbjct: 8   LRVVQLSDCHLFADPEGKLLGLNTQFSLDKVLELIRKEQPNPDLILATGDLSQDASYESY 67

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
           Q     ++ F  P  WL GNHD    M  AL       +  V     W I++LDS + G 
Sbjct: 68  QRLDRTLSGFDVPVYWLEGNHDKPAPMLQALGAHREKMSPCVLNVGNWTIVMLDSTIPGE 127

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
             GEL +  L +L+  L DA   H ++ LHHHP+P  C+WLD   + +A +   V+ +  
Sbjct: 128 VPGELFDGDLSFLDSALRDATGDHLMVCLHHHPVPMECTWLDAQVVGSADKFFQVIDRHE 187

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTL 254
            V+ ++ GH+HQE D   NG R++A PSTCVQFKP   +F +D  +PG+R L+LH +G +
Sbjct: 188 RVRAIIWGHVHQEYDKHRNGVRMMAVPSTCVQFKPKSEDFAVDDASPGYRWLDLHPNGQI 247

Query: 255 TTEVHRLADTRFQPDTASEGY 275
            T V R+    F+ D   +GY
Sbjct: 248 DTAVSRVEGIPFEVDFTIKGY 268


>UniRef50_A4BSE9 Ser/Thr protein phosphatase n=1 Tax=Nitrococcus mobilis Nb-231
           RepID=A4BSE9_9GAMM
          Length = 279

 Score =  201 bits (510), Expect = 3e-50,   Method: Compositional matrix adjust.
 Identities = 106/266 (39%), Positives = 150/266 (56%), Gaps = 1/266 (0%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
            G   +R+LQITDTHLFA     L+GV+T  SY  V+E +       DLI+ATGDL  D 
Sbjct: 14  GGIGSLRVLQITDTHLFADLSGQLVGVDTERSYAEVMEKVLGEFWPVDLILATGDLVHDG 73

Query: 70  SSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDS 129
           S + Y+ F           + +PGNHD    M        ++ +    +G  WQ ++LDS
Sbjct: 74  SESGYRRFKSQFEDLAVRTLVIPGNHDDATIMRRIFSTGRVTWSGSALLGA-WQFVMLDS 132

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
              G   G L+  QL+ LE+ L   PE H L+ LHHHPL  GC W+D+ ++ N  EL  +
Sbjct: 133 SQLGSAAGHLARSQLQMLEQCLTSYPEHHALVCLHHHPLAIGCDWIDRIAVDNGRELFEI 192

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELH 249
           L +   V+ ++ GH+HQE +   +G RLLA+PSTCVQF+P    FT+D + PG+R L+L+
Sbjct: 193 LDRHEQVRGVVWGHVHQEFETIRHGVRLLASPSTCVQFRPGQQEFTIDDVPPGFRWLQLY 252

Query: 250 ADGTLTTEVHRLADTRFQPDTASEGY 275
           ADG + T + R+   +   D   EGY
Sbjct: 253 ADGRIKTSIIRVDAAQGGVDLDCEGY 278


>UniRef50_A0Y9K0 Cyclic AMP phosphodiesterase n=1 Tax=marine gamma proteobacterium
           HTCC2143 RepID=A0Y9K0_9GAMM
          Length = 276

 Score =  199 bits (507), Expect = 7e-50,   Method: Compositional matrix adjust.
 Identities = 109/272 (40%), Positives = 161/272 (59%), Gaps = 3/272 (1%)

Query: 5   LTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGD 64
           L +P+     +++LQITDTHL AQ  E LLG+NT  S + V++ +R  +   DL++ATGD
Sbjct: 7   LLVPIDSHQPIKLLQITDTHLGAQAAETLLGLNTDYSLEQVVDLVRRERPHADLLLATGD 66

Query: 65  LAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQI 124
           ++   +  +Y  + +         +WLPGNHD   AM  A +D G   A    IG  W I
Sbjct: 67  ISSCGAGQSYHRYRQLTKGIADQTLWLPGNHDTVAAMREAAKD-GNEMAGCATIG-NWHI 124

Query: 125 LLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAG 184
           ++L+S+  G   G LS+ +L  L   L  + E + L+ LHHHP+  GC WLD+  + NA 
Sbjct: 125 IMLNSKTPGKVGGSLSDKELAKLRVGLQQSREGYALVCLHHHPVSIGCDWLDEQKVSNAE 184

Query: 185 ELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWR 244
            L +VL +F HV+ LL GH+HQ++D   NG +L+ATPSTC+QF    ++F LD ++PG+R
Sbjct: 185 TLFSVLDEFTHVRGLLWGHVHQQIDQQRNGVKLMATPSTCIQFAADSADFKLDRLSPGYR 244

Query: 245 TLELHADGTLTTEVHRLADTRFQPD-TASEGY 275
            L+L  +G + T V R++   F  D   S GY
Sbjct: 245 WLDLQENGDIETGVSRVSGVVFDIDYDDSSGY 276


>UniRef50_B8HUH6 Metallophosphoesterase n=2 Tax=Chroococcales RepID=B8HUH6_CYAP4
          Length = 266

 Score =  195 bits (495), Expect = 1e-48,   Method: Compositional matrix adjust.
 Identities = 111/261 (42%), Positives = 152/261 (58%), Gaps = 2/261 (0%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + I+Q++DTHLFA     L+G+NT ++ +AVL+ +       DL++ TGDL+QD+S  +Y
Sbjct: 8   LHIVQLSDTHLFADLQGQLVGLNTADALKAVLDQVAQLSPRPDLLLLTGDLSQDESVQSY 67

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
            H  + +A    P  WLPGNHD   AM   L     S     ++G  WQ LLL+SQV G 
Sbjct: 68  THLRDWLAPLDIPVHWLPGNHDNLQAMAQVLLPPLYSGPSTFYLGG-WQFLLLNSQVPGK 126

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
            +GELS   L WLE  L   P+R +L+ LHH PL     WLD   LRN   L  ++ + P
Sbjct: 127 VYGELSPDTLLWLENNLQAHPDRPSLIALHHPPLSISTPWLDSSRLRNPEPLLELIDRHP 186

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTL 254
            VK +  GHIHQE   +  G   L++PSTCVQF P  S F +D + PG+R L L+ DG  
Sbjct: 187 QVKLVSFGHIHQEFAAERRGVIYLSSPSTCVQFLPCSSQFAIDPMPPGFRRLMLYPDGQF 246

Query: 255 TTEVHRLADTRFQPDTASEGY 275
            TEV R+ +  +Q D A++GY
Sbjct: 247 HTEVMRV-EFSYQFDLAAQGY 266


>UniRef50_Q21NU3 Metallophosphoesterase n=3 Tax=Gammaproteobacteria
           RepID=Q21NU3_SACD2
          Length = 271

 Score =  192 bits (489), Expect = 7e-48,   Method: Compositional matrix adjust.
 Identities = 111/264 (42%), Positives = 155/264 (58%), Gaps = 9/264 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +R++QITD HL +Q  E +LG++T +S   VLE I+  +   DLI+ATGD++ D  +A+Y
Sbjct: 14  LRVVQITDCHLGSQPGELMLGLDTDQSLFDVLELIQNSEPTPDLILATGDISNDGGAASY 73

Query: 75  QHFAEGIASFRAPCV---WLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQV 131
           Q F + I +   P V   WLPGNHD    M        I P +  +  + W ++LLDS++
Sbjct: 74  QRFID-IVNHYFPGVALAWLPGNHDDPLNM----DQVDILPIEAHYRAQGWNLILLDSRI 128

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
                GEL   +L  L+ +L  A    T++ LHH P+P G  W+DQ+ ++NA     VL 
Sbjct: 129 PMEEGGELHPNELMRLDAELK-ANSEPTMVFLHHQPVPVGSEWIDQYVVKNAEAFFDVLD 187

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHAD 251
           K+ HVK +  GH+HQE     N   LLATPSTCVQF P    F LDTI PG+R+  L+AD
Sbjct: 188 KYDHVKAVSWGHVHQEFQDSRNNVTLLATPSTCVQFAPKSKPFKLDTIMPGYRSYSLNAD 247

Query: 252 GTLTTEVHRLADTRFQPDTASEGY 275
           G+ T+EV R+    +  D AS GY
Sbjct: 248 GSFTSEVKRIQTKAYAIDFASTGY 271


>UniRef50_B0C4F0 3',5'-cyclic-nucleotide phosphodiesterase n=1 Tax=Acaryochloris
           marina MBIC11017 RepID=B0C4F0_ACAM1
          Length = 265

 Score =  191 bits (484), Expect = 3e-47,   Method: Compositional matrix adjust.
 Identities = 103/267 (38%), Positives = 150/267 (56%), Gaps = 2/267 (0%)

Query: 9   LAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQD 68
           +   + + I Q++D HLFA     LLG+NT+ S +AV++ ++      D ++ TGDLAQD
Sbjct: 1   MKKSSPLLIAQLSDLHLFANPDRDLLGLNTFSSLEAVVQKLKQLPVLPDQLLLTGDLAQD 60

Query: 69  QSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLD 128
           ++  AYQ     IA  + P  WLPGNHD  P M +          K   +G+ W  LLLD
Sbjct: 61  ETPIAYQQIQSLIAPLQIPTYWLPGNHDHLPTMQATFTAPSFQAHKSYQMGD-WHFLLLD 119

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           S V G  +G LS   L+WL ++L     + TL+ LHH P      WLDQ  L+N+ +L  
Sbjct: 120 SSVTGKVYGGLSPESLDWLNQELEQCDPQPTLIALHHPPFAIKSDWLDQIGLQNSDDLFA 179

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLEL 248
           +L +  HVK ++ GHIHQ+ +        L+TPSTC+QF PH   F LD   PG+R  +L
Sbjct: 180 ILDRHSHVKLVVFGHIHQQFEHQRRSIHYLSTPSTCIQFAPHSKTFALDHAQPGFRLFQL 239

Query: 249 HADGTLTTEVHRLADTRFQPDTASEGY 275
           + DG+  TE+HR+   +   D +++GY
Sbjct: 240 YGDGSFETEIHRVMFEK-TLDFSAKGY 265


>UniRef50_A0YY40 3',5'-cyclic-nucleotide phosphodiesterase n=1 Tax=Lyngbya sp. PCC
           8106 RepID=A0YY40_9CYAN
          Length = 276

 Score =  191 bits (484), Expect = 3e-47,   Method: Compositional matrix adjust.
 Identities = 98/249 (39%), Positives = 147/249 (59%), Gaps = 2/249 (0%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++++QI+DTHLFA   + ++G+ T +S  AVL+ IR      D+++ TGDL+QD++S +Y
Sbjct: 7   IQVIQISDTHLFANPDQKMMGLTTADSLIAVLDRIRQLNINPDVLLITGDLSQDETSKSY 66

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
           Q     I  F     W+PGNHD      S L+   IS  K+ F    W+ +LL+SQ  G 
Sbjct: 67  QQLQALIQPFNTSTYWIPGNHDDLSVAESILKKTPIS-IKKAFNISNWKFILLNSQCPGK 125

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
            HGEL+   L  L+ +L   PE+ TL+ LHH P+  G  W+D+  LRN+ +L  V+ ++ 
Sbjct: 126 VHGELTPESLNDLDSQLQQHPEQPTLIALHHPPVLIGSEWMDKIKLRNSEDLFAVIDRYS 185

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA-PGWRTLELHADGT 253
            VK ++ GHIHQE +   NG      PSTCVQFKP     T D +A PG+R L L+++G 
Sbjct: 186 QVKLVIFGHIHQEFETIRNGVVYWGCPSTCVQFKPQSVELTFDQVATPGFRVLTLYSNGE 245

Query: 254 LTTEVHRLA 262
             +++ R +
Sbjct: 246 YNSKIERTS 254


>UniRef50_Q606D3 Cyclic AMP phosphodiesterase n=1 Tax=Methylococcus capsulatus
           RepID=Q606D3_METCA
          Length = 259

 Score =  190 bits (483), Expect = 4e-47,   Method: Compositional matrix adjust.
 Identities = 103/246 (41%), Positives = 146/246 (59%), Gaps = 3/246 (1%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           +LQ+TD+H+         G ++  S  AV++    +Q  FDL++ TGDLAQ+    +Y+ 
Sbjct: 9   LLQLTDSHILPDAESRFYGSDSAASLGAVID--HANQRRFDLVLFTGDLAQEPVPQSYRR 66

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPH 136
            A   A+  APC WLPGNHD +PA+   + ++     + V    +W I+ LDS V G   
Sbjct: 67  LAGICAALPAPCHWLPGNHD-EPALARHVLESTPLLHQPVIRRGRWLIVCLDSTVPGSAG 125

Query: 137 GELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHV 196
           G LS  Q + LER L+  P  HTL+ LHHHP+P+G +W+D   L NAGE   VL + P V
Sbjct: 126 GSLSTGQFDLLERTLSRHPSLHTLVALHHHPVPSGSAWMDTMILDNAGEFFAVLRRHPQV 185

Query: 197 KYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTT 256
           K ++ GH HQ  D++  G R+L TPSTC+QF+P    F LD   PG+R LEL  DG++ T
Sbjct: 186 KAVVHGHTHQVADVEIEGTRVLGTPSTCIQFRPASQTFALDAERPGYRWLELGPDGSVAT 245

Query: 257 EVHRLA 262
            + R+A
Sbjct: 246 GICRVA 251


>UniRef50_A4A8X3 Icc protein n=2 Tax=unclassified Gammaproteobacteria
           RepID=A4A8X3_9GAMM
          Length = 278

 Score =  189 bits (480), Expect = 8e-47,   Method: Compositional matrix adjust.
 Identities = 106/267 (39%), Positives = 150/267 (56%), Gaps = 13/267 (4%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           VR++Q+TDTHL A     LLG++T  S QAV++ +     + D ++ TGDLA   +  AY
Sbjct: 18  VRVVQLTDTHLKAHDGGKLLGLDTDYSLQAVIDLVNSEYPDPDFVLGTGDLADSGAGDAY 77

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKR----VFIGEQWQILLLDSQ 130
                          WLPGNHD +  M      A +  A+R    + +G  WQI++LDSQ
Sbjct: 78  NRLIGYFDQVSTEHFWLPGNHDLREVM------ADVGGARRLPGEIRVG-AWQIVMLDSQ 130

Query: 131 VFGVPHGELSEFQLEWLERKLADAPER--HTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           + G   G L   +L+ LE  LA + E   +TL+ +HH P+P GC WLD+  + +A     
Sbjct: 131 LPGEVGGHLGRGELQRLEECLAASAEAGLYTLICMHHQPVPVGCDWLDEQMVSDADSFFE 190

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLEL 248
           +L ++P V+ +L GH+HQ LD      RLL TPSTCVQF P  ++F +D+ APG+R LEL
Sbjct: 191 ILGRYPQVRGVLWGHVHQALDQRCEDLRLLCTPSTCVQFLPKQTDFAVDSRAPGYRWLEL 250

Query: 249 HADGTLTTEVHRLADTRFQPDTASEGY 275
             DGT+ T+V R     F  D  + GY
Sbjct: 251 EPDGTIRTDVSRAESQIFPVDKEASGY 277


>UniRef50_UPI0001698C6A Calcineurin phosphoesterase C-terminal domain protein n=1
           Tax=Endoriftia persephone 'Hot96_1+Hot96_2'
           RepID=UPI0001698C6A
          Length = 279

 Score =  187 bits (476), Expect = 3e-46,   Method: Compositional matrix adjust.
 Identities = 101/264 (38%), Positives = 144/264 (54%), Gaps = 1/264 (0%)

Query: 12  EARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
           +  + +LQ++D+H++A +   L+G+NT +S   V+   R      DL++ATGDL  D S+
Sbjct: 17  DGAITLLQLSDSHIYADQDRCLVGINTQDSLDQVIALARQQLSTPDLLLATGDLVHDASA 76

Query: 72  AAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQV 131
           A YQ  AE +++F  P   LPGNHD    M   L    +     +  G  W I+ LDS +
Sbjct: 77  AGYQRIAERLSAFGCPVYCLPGNHDVPKVMQEHLNRPPLYCLPSLQRGN-WSIIFLDSTI 135

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
            G P G L + QLE L   L   P+ HTL+ +HHHP+P G +W+D  +L N   L  +L 
Sbjct: 136 PGKPGGHLDDAQLELLSETLNRHPKHHTLITMHHHPVPVGSAWMDTMALVNPEPLFHLLE 195

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHAD 251
           +   V+ +L GHIHQE D    G RL+ TPSTC+QF      F +D+  PG+R + L   
Sbjct: 196 QHSQVRAVLFGHIHQEFDTKHRGIRLIGTPSTCIQFIAGQDKFGIDSKPPGYRAMVLLES 255

Query: 252 GTLTTEVHRLADTRFQPDTASEGY 275
           G + TEV  L       D +S GY
Sbjct: 256 GEIRTEVRLLQALPLGLDLSSGGY 279


>UniRef50_Q8YLG0 3',5'-cyclic-nucleotide phosphodiesterase n=3 Tax=Nostocaceae
           RepID=Q8YLG0_ANASP
          Length = 266

 Score =  184 bits (466), Expect = 4e-45,   Method: Compositional matrix adjust.
 Identities = 94/247 (38%), Positives = 145/247 (58%), Gaps = 1/247 (0%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + I QITD HL A + + L G++T ES+ AV++ +   + E DL++ TGDL+ D +  +Y
Sbjct: 7   ISIAQITDIHLLASESQRLQGISTTESFLAVMKRLEELRPELDLLLMTGDLSDDGTPESY 66

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
           ++    + S +    WLPGNHD   AM   L + G+   ++ F    W  +LL+S V   
Sbjct: 67  ENLQHYLNSLQIATYWLPGNHDCAIAMDKIL-NLGMVSRRKSFQRGNWNFILLNSSVTDC 125

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
            +G LS   L+WL+ +L   P   TL+ LHH PL    +W+D+  L+N+ EL  V+ ++P
Sbjct: 126 VYGYLSATTLDWLDSELKMLPNNPTLIALHHPPLSVNSAWIDRSCLQNSQELFAVIDRYP 185

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTL 254
            VK +L GHIHQE     +    L +PSTC QF+   + F ++   PG+R L+L+ADGT 
Sbjct: 186 QVKLVLFGHIHQEFRRQRHNVHYLGSPSTCYQFQSQSTTFAINQELPGFRLLKLYADGTW 245

Query: 255 TTEVHRL 261
           TT++ R+
Sbjct: 246 TTKIERV 252


>UniRef50_C7R6J1 Metallophosphoesterase n=1 Tax=Kangiella koreensis DSM 16069
           RepID=C7R6J1_KANKD
          Length = 274

 Score =  181 bits (460), Expect = 2e-44,   Method: Compositional matrix adjust.
 Identities = 96/265 (36%), Positives = 147/265 (55%), Gaps = 1/265 (0%)

Query: 11  GEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQS 70
           G   + +L ++D HLFA    +LLGVNT ES+ AVLE IR    + D+I+ TGD++QD S
Sbjct: 11  GRPEMTVLHLSDPHLFADDQGSLLGVNTQESFCAVLEDIRARAIDPDVIIVTGDISQDYS 70

Query: 71  SAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQ 130
             +YQ FA+ +A F  P   L GNHD    + S L +A +   K++ + + WQIL++ S 
Sbjct: 71  KDSYQFFAKQMAKFGKPVFTLAGNHDEVEYLTSFLSEAPLFNHKQI-LTDHWQILMISSH 129

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
           +    HG +   +L+W  R L +  +  T++ +HHHP+P G  WLD+  + N  EL  ++
Sbjct: 130 IEDEVHGRIDPSELKWARRCLEENSDLPTMIYMHHHPVPVGSDWLDEIGVSNKDELLELV 189

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHA 250
            + P VK    GH+HQ  +   +     + PSTCVQFK H ++F      PG+   + HA
Sbjct: 190 TEHPQVKLCGFGHVHQFSEYKIDNAVYCSVPSTCVQFKRHSADFAASGETPGYAVYQCHA 249

Query: 251 DGTLTTEVHRLADTRFQPDTASEGY 275
           DG +  + +R+       + A  GY
Sbjct: 250 DGVIDKQNYRVDHYLPSVNFAISGY 274


>UniRef50_B8KUM1 Cyclic AMP phosphodiesterase n=1 Tax=gamma proteobacterium NOR51-B
           RepID=B8KUM1_9GAMM
          Length = 277

 Score =  173 bits (438), Expect = 6e-42,   Method: Compositional matrix adjust.
 Identities = 103/265 (38%), Positives = 145/265 (54%), Gaps = 7/265 (2%)

Query: 13  ARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA 72
           A +++LQITDTHL  Q+   LL V+T  S  AV+ A+       D ++ TGD+A   +  
Sbjct: 17  ATLKLLQITDTHLMQQRGGRLLNVDTDASLSAVV-ALASQSLPADALLITGDIAGAGAGD 75

Query: 73  AYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVF 132
           AY    E ++  +AP  WLPGNHD   A    L        KR  I   WQ+L+LDSQV 
Sbjct: 76  AYYRLEEALSPLQAPSFWLPGNHDDGHACADELS----WHFKRQVIFPHWQVLMLDSQVR 131

Query: 133 GVPHGELSEFQLEWLERKLA--DAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
           G   G L++ +L+ L   ++  +A  RH L+ LHH   P GC WLD   + NA ++   L
Sbjct: 132 GEVGGILAQAELDALVTAVSESNASGRHLLVALHHPLWPLGCDWLDSQRVANADDVAACL 191

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHA 250
               +   ++ GH+HQE D    G R L TPSTC+QF  +  +F +D   PG+R L+L A
Sbjct: 192 EMAENKVVVISGHVHQESDAIHRGARYLTTPSTCIQFAKYSPDFKVDDSGPGYRWLDLQA 251

Query: 251 DGTLTTEVHRLADTRFQPDTASEGY 275
           DG ++T V R+ +  F  D  S+GY
Sbjct: 252 DGFVSTGVERVTEVSFPVDLDSDGY 276


>UniRef50_Q1YUP4 CAMP phosphodiesterase n=1 Tax=gamma proteobacterium HTCC2207
           RepID=Q1YUP4_9GAMM
          Length = 261

 Score =  171 bits (434), Expect = 2e-41,   Method: Compositional matrix adjust.
 Identities = 101/263 (38%), Positives = 138/263 (52%), Gaps = 3/263 (1%)

Query: 13  ARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA 72
           + V I QITD HL A + E L GV T+ES+ A L+A         L++ TGDLA D  + 
Sbjct: 2   STVHITQITDLHLGADEQETLGGVTTFESFNAALQASEDQGRADSLLLLTGDLASDYQAG 61

Query: 73  AYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVF 132
           AYQ   + +       +WLPGNHD    M + L      P  R++    W ILLLDS   
Sbjct: 62  AYQLLNKVLTEKHRQALWLPGNHDHLETMEANLT---AFPRVRIYEAGAWGILLLDSSKA 118

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
           G P G  SE +L++ E+ L     +  L+ +HH P+    +WLDQ  + N   L  +L  
Sbjct: 119 GQPGGHFSEAELQFAEQGLKHLAGKFVLVAVHHSPVRVNSAWLDQQQIDNHHRLYDLLVA 178

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADG 252
              VK ++ GH+HQ  D  W    + +TPS+CVQF+ H  +F L    PG+R L+LH DG
Sbjct: 179 HGQVKAVVTGHVHQHHDSLWGDLPVYSTPSSCVQFEQHSHDFGLADKPPGYRWLDLHDDG 238

Query: 253 TLTTEVHRLADTRFQPDTASEGY 275
           +L T V  L D   Q D +  GY
Sbjct: 239 SLDTGVEFLKDFAQQCDRSCAGY 261


>UniRef50_B8GLR4 Icc protein n=1 Tax=Thioalkalivibrio sp. HL-EbGR7
           RepID=B8GLR4_THISH
          Length = 266

 Score =  170 bits (431), Expect = 5e-41,   Method: Compositional matrix adjust.
 Identities = 97/244 (39%), Positives = 133/244 (54%), Gaps = 3/244 (1%)

Query: 17  ILQITDTHLFAQKHEALLGV--NTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++QITD HL A   E + GV  +T  +   VL  IR    + DL++ATGDLA+    A Y
Sbjct: 9   VVQITDPHLGAPS-EGMYGVTIDTGATLARVLADIRARCPQADLMLATGDLAERPVPATY 67

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
               + ++    P   LPGNHD    M  AL DA      RV   E W +++LDS + G 
Sbjct: 68  AQLRKALSGLPMPVHCLPGNHDEPQVMEEALADAPGIDCARVITREDWVVVMLDSTIPGH 127

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
             G L   +LE+LE  L+  P R+ L+ LHH  +  G  W+D+  L +AG L  +  +  
Sbjct: 128 AGGALDADELEFLEETLSRHPARNALICLHHPVVAVGSRWMDRMKLADAGALFQITDRHT 187

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTL 254
            V+ LL GHIHQ+ +    G RL+ TPSTC+QF P   +F LD + P WR L LH DG +
Sbjct: 188 QVRGLLFGHIHQDFEAVRKGVRLIGTPSTCLQFLPESDDFALDALPPAWRHLTLHPDGRI 247

Query: 255 TTEV 258
            T+V
Sbjct: 248 DTQV 251


>UniRef50_Q1C384 Regulator of lacZ n=8 Tax=Enterobacteriaceae RepID=Q1C384_YERPA
          Length = 137

 Score =  169 bits (428), Expect = 9e-41,   Method: Compositional matrix adjust.
 Identities = 82/114 (71%), Positives = 94/114 (82%)

Query: 1   MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV 60
           MESL  LP+A  ARVRILQITDTHLFA +HE LLGVNT+ SY+AVL+AI   QH FDL+V
Sbjct: 1   MESLFKLPMASGARVRILQITDTHLFAGEHETLLGVNTFHSYRAVLDAIIAEQHPFDLVV 60

Query: 61  ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAK 114
           ATGDLAQD S AAYQ+FA+GI+    PCVWLPGNHDFQPAM+ AL +AGI+P K
Sbjct: 61  ATGDLAQDHSVAAYQNFAKGISRLPVPCVWLPGNHDFQPAMFDALAEAGIAPFK 114


>UniRef50_C5SEA9 Calcineurin phosphoesterase domain protein n=1 Tax=Allochromatium
           vinosum DSM 180 RepID=C5SEA9_CHRVI
          Length = 261

 Score =  168 bits (426), Expect = 1e-40,   Method: Compositional matrix adjust.
 Identities = 103/264 (39%), Positives = 141/264 (53%), Gaps = 8/264 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +R+LQ+TD HLF      LLG+ T  S+++VL          D ++ TGDL  D++   Y
Sbjct: 3   LRLLQLTDPHLFGDPGGQLLGITTRRSFESVLALALSESPAPDALILTGDLVHDETPVGY 62

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAG-ISPAKRVFIGEQWQILLLDSQVFG 133
           ++  E +     P   + GNHD Q  M   L  A  +S A R   G  W ++ LDS   G
Sbjct: 63  RYLRERLNRTGIPYYCIGGNHDIQSLMMEQLGPAALVSVALRRLDG--WNLIFLDSSEPG 120

Query: 134 VPHGELSEFQLEWLERKLADAPERH-TLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
              G L+E QL  L   LAD  ER   L+ LHHHP   G +W+D+  + N   L  +  +
Sbjct: 121 SDGGRLTETQLTQLTDLLAD--ERAPALICLHHHPAAVGSAWIDRIGVANGASLLDLCNR 178

Query: 193 FPHVKYLLCGHIHQELDLDWNGR-RLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHAD 251
            PHVK +L GH+HQE    W+G  RLL  P+TC QF+P   +F +D I PG+R L L+ D
Sbjct: 179 HPHVKAVLFGHVHQEFSA-WHGDCRLLGAPATCFQFEPRSRDFAIDEIPPGYRELMLYPD 237

Query: 252 GTLTTEVHRLADTRFQPDTASEGY 275
           G LTT V RL +   +P   + GY
Sbjct: 238 GRLTTRVVRLVEYAERPLYQAGGY 261


>UniRef50_Q2JPZ0 Icc protein n=2 Tax=Synechococcus RepID=Q2JPZ0_SYNJB
          Length = 264

 Score =  167 bits (424), Expect = 2e-40,   Method: Compositional matrix adjust.
 Identities = 102/263 (38%), Positives = 143/263 (54%), Gaps = 3/263 (1%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           V ++QI+D HLFA+ H  LLGV+T  S+  V +AI       DL++ TGDL+QD S+A+Y
Sbjct: 3   VYVVQISDLHLFAKPHHRLLGVDTEASFLQVQKAIAALDPLPDLLLLTGDLSQDGSAASY 62

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
                 + +      WL GNHD    M   L    +    + F  E W  +LL+S V G 
Sbjct: 63  ARLRAHLQALPIDTYWLAGNHDRLHTMNQELHAERLF-GDKSFSRENWSFILLNSLVPGK 121

Query: 135 PHGELSEFQLEWLERKL--ADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
             G L+E  L WL ++L  + A + H LL LHH P     +WLDQ +L+    L  VL +
Sbjct: 122 DSGYLTERTLLWLRQELQRSKAAQHHVLLALHHPPFSVDSAWLDQSALQQPERLFGVLDE 181

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADG 252
           F H++ ++ GHIHQ+L     G   LA PSTCVQF+P    F L+ I P  R + L  DG
Sbjct: 182 FDHIRLVVFGHIHQDLHRRREGVDYLACPSTCVQFRPKSPQFGLEVIPPALRQIWLERDG 241

Query: 253 TLTTEVHRLADTRFQPDTASEGY 275
           +  T+V R+     +P+ A +GY
Sbjct: 242 SFKTQVQRVGAALQRPNLALKGY 264


>UniRef50_A3M1D0 Cyclic 3'5'-adenosine monophosphate phosphodiesterase n=17
           Tax=Acinetobacter RepID=A3M1D0_ACIBT
          Length = 270

 Score =  166 bits (421), Expect = 6e-40,   Method: Compositional matrix adjust.
 Identities = 95/259 (36%), Positives = 137/259 (52%), Gaps = 3/259 (1%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           I+QITDTHL        +G+N  ES+ A+++ I     E D I+ TGDLAQ  +   Y+ 
Sbjct: 15  IIQITDTHLLEYPQLEFVGMNPEESFHAIIQQILKQHPEADAIIHTGDLAQAPTPITYKR 74

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPH 136
           +   + +   P     GNHD     +  L +        V +G  W++++L+S V G   
Sbjct: 75  YINFMQTLGLPFFQTLGNHD--NVDHFPLHNENHQQPVVVGLGN-WRVIMLNSAVKGKVD 131

Query: 137 GELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHV 196
           G LS  QLE L   L    +   LL  HHHP      W+D H L+N+  L   L+ F +V
Sbjct: 132 GHLSSEQLENLANLLEQFADHPVLLACHHHPFAMKSKWIDHHKLQNSNALLDTLSPFQNV 191

Query: 197 KYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTT 256
           K L+CGH+HQ+    W G    +TPST VQFKP  ++F LD  APG+R + L+ DG+  T
Sbjct: 192 KALVCGHVHQDSLNIWQGIEFFSTPSTSVQFKPFSNDFALDQNAPGYRYIRLNNDGSFET 251

Query: 257 EVHRLADTRFQPDTASEGY 275
           +V RL + + + +T   GY
Sbjct: 252 KVFRLENFKTRINTDISGY 270


>UniRef50_Q0EZ19 Ser/Thr protein phosphatase n=1 Tax=Mariprofundus ferrooxydans PV-1
           RepID=Q0EZ19_9PROT
          Length = 265

 Score =  166 bits (420), Expect = 8e-40,   Method: Compositional matrix adjust.
 Identities = 99/258 (38%), Positives = 144/258 (55%), Gaps = 8/258 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +++L I+D+HL++     L G+   +S+ AVL          D ++  GD+AQD+    Y
Sbjct: 3   LQLLHISDSHLYSDPASLLKGIRPHDSFTAVLADAYRSFPVVDAVILGGDMAQDEQPETY 62

Query: 75  QHFAEGIASFRAPCVWLPGNHD----FQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQ 130
                 +  ++AP +  PGNH         +  AL+  G + + R+  G +WQI+ L+S 
Sbjct: 63  HRLVSMLPDWQAPMMLTPGNHAALGYLSGTLIPALRARG-AYSDRLLSG-RWQIITLNSH 120

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
             G   G L   +LE L++ L+ +   HTL+ LHHHP+P G  WLD+  L N   L  ++
Sbjct: 121 HPGHISGLLPASELERLQQLLSVSAGIHTLIALHHHPIPIGSRWLDEIDLVNRDALWEIV 180

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHA 250
            K  HV+ LLCGHIHQ  D   +G R+L +PSTCVQF P   NF L  I+PG+R LEL  
Sbjct: 181 HKHSHVRALLCGHIHQSFDTIHDGVRVLGSPSTCVQFTPGTDNFALADISPGYRWLELLD 240

Query: 251 DGTLTTEVHRLADTRFQP 268
           DG ++T VHR+  T F P
Sbjct: 241 DGNISTTVHRI--TGFIP 256


>UniRef50_B7S0L2 Calcineurin-like phosphoesterase C-terminal domain family protein
           n=1 Tax=marine gamma proteobacterium HTCC2148
           RepID=B7S0L2_9GAMM
          Length = 279

 Score =  162 bits (411), Expect = 9e-39,   Method: Compositional matrix adjust.
 Identities = 98/263 (37%), Positives = 141/263 (53%), Gaps = 4/263 (1%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           VR++QITDTHL A     LL ++T  S + V+E     +   D ++ TGDL+   S  AY
Sbjct: 18  VRLVQITDTHLCANPGGTLLDMDTDRSLKLVIERALQERGTPDGVLCTGDLSDQGSLQAY 77

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
           +     +    AP  WLPGNHD    M +A+ D        V  G  WQ++LL+SQ+ G 
Sbjct: 78  RRLIAHLQEIPAPDFWLPGNHDDLSEMQAAV-DTSDRLCAEVLAG-NWQVILLNSQIPGE 135

Query: 135 PHGELSEFQLEWLERKL--ADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
             G L   +LE L   L  A A   H+L+ LHH P+  G +W+DQ  + +A +   ++  
Sbjct: 136 VGGRLGSDELEKLRLALERAQAEGLHSLVCLHHQPVAIGSAWIDQQMVEDADQFWEIVDA 195

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADG 252
              VK +L GH+HQ++D       L+A+PS+CVQF P  + F  D   PG+R L+L +DG
Sbjct: 196 ASSVKGVLWGHVHQQIDERRGDIALMASPSSCVQFAPGSAMFKADDKPPGYRWLDLCSDG 255

Query: 253 TLTTEVHRLADTRFQPDTASEGY 275
           ++ T V R+    F  D  S GY
Sbjct: 256 SINTGVSRVTGVDFTVDLESGGY 278


>UniRef50_Q2KTW6 cAMP phosphodiesterase n=5 Tax=Bordetella RepID=Q2KTW6_BORA1
          Length = 270

 Score =  160 bits (406), Expect = 4e-38,   Method: Compositional matrix adjust.
 Identities = 102/255 (40%), Positives = 142/255 (55%), Gaps = 7/255 (2%)

Query: 8   PLAG-EARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLA 66
           PLA  +A   +LQ++D+HL A     +LGVNT  S +AV++  R  + + +L++ TGDLA
Sbjct: 5   PLAAHDAPALLLQLSDSHLMADPDARMLGVNTDASLRAVIDLARRQEGQPELMLLTGDLA 64

Query: 67  QDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILL 126
           QD S  AY+     +    AP   LPGNHD    M   L D  ISP   V+    W+I++
Sbjct: 65  QDGSPQAYRRLQAHLRG--APVRCLPGNHDAPEVMRQILAD-WISP---VYDLPGWRIIM 118

Query: 127 LDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGEL 186
           LDS V G   G L E QL  L++ + DA  RH L+ LHH+      +W D   + NA  +
Sbjct: 119 LDSTVPGEDFGHLDEAQLAVLDQAIKDAGPRHVLVALHHNLARVDGNWQDPMMVDNAAAV 178

Query: 187 DTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTL 246
              L+  P  +  L GHIHQE D   +  RLL TPSTC QF  +     +D  APG+R +
Sbjct: 179 FARLSAHPQTRIALWGHIHQEFDCRHHHLRLLGTPSTCFQFTLNNGQHAIDAKAPGYRWI 238

Query: 247 ELHADGTLTTEVHRL 261
           +L+ADG++ T + RL
Sbjct: 239 KLYADGSIATGIRRL 253


>UniRef50_A0Z341 Metallophosphoesterase n=1 Tax=marine gamma proteobacterium
           HTCC2080 RepID=A0Z341_9GAMM
          Length = 275

 Score =  156 bits (395), Expect = 6e-37,   Method: Compositional matrix adjust.
 Identities = 91/263 (34%), Positives = 135/263 (51%), Gaps = 11/263 (4%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           ++Q+TD HL   +   LL V+T +S  AVLE +       D ++ TGD+A D +  AYQ 
Sbjct: 19  LVQVTDAHLMGVRGGRLLNVDTDDSLAAVLELVEARPEPPDALLITGDIAGDGAGDAYQR 78

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAK--RVFIGEQWQILLLDSQVFGV 134
           FA+ + +  AP  WLPGNHD          ++ +   +  R      W +++LDSQ    
Sbjct: 79  FAQALEAIPAPSFWLPGNHD-------DCDESVVDRERFIRTVTNPHWLVVMLDSQQTDE 131

Query: 135 PHGELSEFQLEWLERKL--ADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
             G L+  +L+ L + +  A+   +H L+ LHH   P GC WLD   + N+   +  + +
Sbjct: 132 VGGYLAANELDALSQAVDRANQEGKHLLVALHHPLQPVGCDWLDPQRVANSSAFELEVQR 191

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADG 252
             +   ++ GH+HQE D      R L TPSTC+QF P+  NF +   APG+R L L   G
Sbjct: 192 CRNQVVVIAGHVHQESDQVSGNIRYLTTPSTCIQFAPNQVNFKVGDQAPGYRWLRLAPSG 251

Query: 253 TLTTEVHRLADTRFQPDTASEGY 275
            + T V R+ D  F  D  S GY
Sbjct: 252 EIETGVERVTDREFPVDLDSGGY 274


>UniRef50_Q3JEM1 Metallophosphoesterase n=2 Tax=Nitrosococcus oceani
           RepID=Q3JEM1_NITOC
          Length = 270

 Score =  154 bits (389), Expect = 3e-36,   Method: Compositional matrix adjust.
 Identities = 100/263 (38%), Positives = 138/263 (52%), Gaps = 6/263 (2%)

Query: 1   MESLLTLPLAGEAR--VRILQITDTHLFAQKHEALL--GVNTWESYQAVLEAIRPHQHEF 56
           M SL  L +A +    + +LQ+TD+HL A   EA L   +NT  S  AVL  I+      
Sbjct: 1   MTSLPHLKIANDRSEFINVLQLTDSHLLADS-EAFLWNDLNTRRSLVAVLNHIQQQGLLG 59

Query: 57  DLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV 116
           DL+V +GD+A+     AY    E       P   LPGNHD    M   L    +S    V
Sbjct: 60  DLMVISGDIAEKAEPEAYYWLLERCQELGLPVYCLPGNHDDPVLMDEILNGMNVSTESLV 119

Query: 117 FIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLD 176
            + + WQ++ L+S V    HG LS+ QL +L R LAD+ + +TL+ LHH P+  G  W+D
Sbjct: 120 TL-KNWQLIFLNSVVTQRSHGHLSKGQLGFLNRSLADSLDLNTLIFLHHPPVALGSPWMD 178

Query: 177 QHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTL 236
              + NA +   VL  +P V+ +  GH HQE   +  G +LL +PSTCVQF P   +F L
Sbjct: 179 AMGVDNAADFFAVLDLYPQVRGVAWGHAHQEFHTERQGVQLLGSPSTCVQFVPGSEHFQL 238

Query: 237 DTIAPGWRTLELHADGTLTTEVH 259
           D   PG+R L L   G + T V+
Sbjct: 239 DQRGPGYRWLILLPGGQIETRVY 261


>UniRef50_A8ZM80 Phosphodiesterase, putative n=1 Tax=Acaryochloris marina MBIC11017
           RepID=A8ZM80_ACAM1
          Length = 259

 Score =  152 bits (383), Expect = 1e-35,   Method: Compositional matrix adjust.
 Identities = 100/259 (38%), Positives = 136/259 (52%), Gaps = 17/259 (6%)

Query: 13  ARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA 72
           A + + QI+DTHL A     L G N W+S QAVL+ +  ++ + D I+ TGDLA   S  
Sbjct: 3   APITLAQISDTHLLADTTALLRGTNPWQSLQAVLQQV--NRDQLDGILLTGDLADQGSVV 60

Query: 73  AYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVF 132
           AYQH    I   + P  WLPGNHD   AM+  LQ   +   + + +G  W ++ L+S + 
Sbjct: 61  AYQHLMRAILPLKMPAYWLPGNHDQVEAMHRELQSPQLYGPQAIHLGS-WLLISLNSVLP 119

Query: 133 GVPHGE--LSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
               GE  LS   L+ L+  L   P + T++ LHHHP+  G  WLDQ  ++NA  L T+L
Sbjct: 120 SAQFGEGYLSVSALQQLQSVLTQHPHKPTVIALHHHPVAIGIDWLDQMQVQNADALLTLL 179

Query: 191 AKFPHVKYLLCGHIHQELDLDWN---GRR-----LLATPSTCVQFKPHCSNFTLDTIAPG 242
             FP VK +L GHIH  LD  +     +R         PSTC+Q  P     T  T  PG
Sbjct: 180 ESFPQVKVVLFGHIH--LDFQYQHVFSQRPSPIYFYGCPSTCLQVNPPVP--TDHTHLPG 235

Query: 243 WRTLELHADGTLTTEVHRL 261
           +R L L  +GT  T V R+
Sbjct: 236 FRLLSLDPNGTHRTWVQRV 254


>UniRef50_B1XQ99 Putative 3',5'-cyclic-nucleotide phosphodiesterase n=1
           Tax=Synechococcus sp. PCC 7002 RepID=B1XQ99_SYNP2
          Length = 255

 Score =  149 bits (377), Expect = 8e-35,   Method: Compositional matrix adjust.
 Identities = 94/253 (37%), Positives = 127/253 (50%), Gaps = 9/253 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           V I QITDTHL       + GV T  S+QAVL A++  Q + D ++ TGDLA    + +Y
Sbjct: 2   VLIAQITDTHLLDHPEAEMRGVKTDASFQAVLAAVQ--QFKPDRLILTGDLAHHGEAISY 59

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
           +   + + + + P  WLPGNHD    M   LQ   +SP K V +G  W++LLLDS +   
Sbjct: 60  ERLRDLVEATQIPSYWLPGNHDDPELMAGILQGDYLSPDKNVALG-NWKLLLLDSFLENP 118

Query: 135 PHGE--LSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
            +GE  L   QL WL  +L         + +HHH +PAG  WLDQ  + N  E   ++  
Sbjct: 119 EYGEGFLDTAQLAWLAERLEHHQNSPVAIAIHHHVVPAGVDWLDQIDMTNRAEFWQIVQH 178

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTI----APGWRTLEL 248
            P VK +  GH+H E  +   G     TPSTC Q  P               PG+R  EL
Sbjct: 179 HPQVKTVFFGHVHLEYSVTQGGIPCFGTPSTCTQVTPPDQEPIEGDRQLWEQPGFRLFEL 238

Query: 249 HADGTLTTEVHRL 261
           H DG   T+V R+
Sbjct: 239 HDDGRFQTKVQRI 251


>UniRef50_Q0AC05 Metallophosphoesterase n=1 Tax=Alkalilimnicola ehrlichii MLHE-1
           RepID=Q0AC05_ALHEH
          Length = 251

 Score =  148 bits (374), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 93/251 (37%), Positives = 128/251 (50%), Gaps = 12/251 (4%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAI----RPHQHEFDLIVATGDLAQDQSS 71
           R++QITD HL A   + + G++ W S  AVL AI    RP     DL++ +GDL QD   
Sbjct: 5   RLVQITDCHLSAAPGKRVRGMDPWRSLDAVLAAIGRGPRP-----DLLLVSGDLTQDLGK 59

Query: 72  AAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQV 131
                  E +       + LPGNHD   A+      + +          +WQ+LL+D+  
Sbjct: 60  PVLARLRERLVPLADRVLALPGNHDDPEALARVFPGSPVDTGATSHSLGEWQLLLMDTSR 119

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
            G   GE+   +LE LE  L + P    L   HH PL  G +WLD   L +   L   L 
Sbjct: 120 PGRVEGEMGVQRLEALEFLLHEGP---ALCAGHHPPLACGSAWLDAIGLEDGATLLAWLK 176

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHAD 251
           + P V+ +L GHIHQ LD      RLL TP+T  QF+P  + F LDT  PG+RT++L  +
Sbjct: 177 RHPQVRGMLFGHIHQALDRRQGALRLLGTPATSFQFRPGRARFALDTRLPGYRTVKLWPN 236

Query: 252 GTLTTEVHRLA 262
           G LT+ V R+A
Sbjct: 237 GRLTSRVSRVA 247


>UniRef50_C8PWU2 Calcineurin phosphoesterase domain protein n=1 Tax=Enhydrobacter
           aerosaccus SK60 RepID=C8PWU2_9GAMM
          Length = 275

 Score =  145 bits (366), Expect = 2e-33,   Method: Compositional matrix adjust.
 Identities = 83/255 (32%), Positives = 135/255 (52%), Gaps = 12/255 (4%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           I++++D HLF   ++ + GVNT +++++VL  +R  + + DL+V TGDL  + +   Y  
Sbjct: 18  IIELSDLHLFDDPNKLMNGVNTADTFESVLSLVRQQRDDVDLLVLTGDLCHEPTPQNYDR 77

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAG-----ISPAKRV-----FIGEQWQILL 126
               +     P + +PGNHD    + + L  A      +    R+        + W +LL
Sbjct: 78  LFATLDDVNIPFIAIPGNHDVTLELDNHLPFAQRRHLPVKSDSRLQNCYSIATDYWDLLL 137

Query: 127 LDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGEL 186
           LDS   G  HG++ E  L WL ++LA+A  R   +  HH  +    +WLD+++L NA   
Sbjct: 138 LDSSCEGHSHGKIDEQSLLWLAQQLANA-NRPCAIFCHHPMVLIDSTWLDEYTLINADRF 196

Query: 187 -DTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRT 245
            + V+     +K +  GHIHQE+     G  +   PST +QFKP C ++T+D IAPG R 
Sbjct: 197 WEVVMPYLDRIKAIFVGHIHQEMHKITYGISVFGCPSTSLQFKPLCKDYTIDEIAPGLRW 256

Query: 246 LELHADGTLTTEVHR 260
           + L+ +G L T + R
Sbjct: 257 INLYNNGLLATGIKR 271


>UniRef50_B9ZKN4 Calcineurin phosphoesterase domain protein n=1 Tax=Thioalkalivibrio
           sp. K90mix RepID=B9ZKN4_9GAMM
          Length = 265

 Score =  144 bits (363), Expect = 3e-33,   Method: Compositional matrix adjust.
 Identities = 86/252 (34%), Positives = 127/252 (50%), Gaps = 2/252 (0%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           R++QI+DTHL         G    ++    +    P +   D ++ +GDLA+D   A Y 
Sbjct: 9   RLIQISDTHLGRVPGPIRAGYPDSDTQLERILGALPREPAADALLLSGDLAEDPEPATYA 68

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVP 135
             A  + S R P + L GNHD    + +AL+           +G  W+++ LDS   G  
Sbjct: 69  RLARLLGSRREPMLALAGNHDDCQTLRTALEPETCQVHGERMLGP-WKLIGLDSSTPGEA 127

Query: 136 HGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPH 195
            G L   + E LE+ L+  P+R T++ LHH P+  G +W+D+  L +   L  VL + P 
Sbjct: 128 AGRLDASECERLEKSLSADPDRPTVVALHHPPVAIGSAWMDRLGLLDPDALFAVLDRHPQ 187

Query: 196 VKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLD-TIAPGWRTLELHADGTL 254
           V+  L GHIHQ+         LL +PSTCVQF P    F +D  +  G+R L+LH DG  
Sbjct: 188 VRACLFGHIHQDFRARRGAIELLGSPSTCVQFTPGSEEFAVDAALDAGYRILDLHPDGRF 247

Query: 255 TTEVHRLADTRF 266
            T+V R+  TR 
Sbjct: 248 DTQVVRVPGTRI 259


>UniRef50_B5JTJ8 Metallophosphoesterase n=1 Tax=gamma proteobacterium HTCC5015
           RepID=B5JTJ8_9GAMM
          Length = 250

 Score =  137 bits (346), Expect = 3e-31,   Method: Compositional matrix adjust.
 Identities = 85/248 (34%), Positives = 126/248 (50%), Gaps = 2/248 (0%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           R+LQ++D H+ A     L G +T E  + +LE I+     F  ++ +GDL+   S+ +YQ
Sbjct: 5   RLLQLSDCHITADADTQLRGYDTHELLRKLLEQIKKRDRHFHALLLSGDLSDRGSAESYQ 64

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVP 135
                ++  + P   LPGNHD    M   L+   I+          W++L+L+SQ  G  
Sbjct: 65  RLNALLSFCKKPIYALPGNHDQLLEMRDQLR--KIAQCVHSADLGTWRLLMLNSQQAGKT 122

Query: 136 HGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPH 195
            G LSE +L  L+  L       +L+ +HH P     +W+D  +L+N  EL  ++     
Sbjct: 123 EGYLSEDELSRLKLWLDHGKNIPSLVAVHHPPCSIHSAWMDAINLQNGDELLDIVKSHHQ 182

Query: 196 VKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLT 255
           VK +  GH+HQ  D   +G RLL TPSTC QF P    F +D   PG+R  ELH +G   
Sbjct: 183 VKAISFGHVHQAFDQTIHGVRLLGTPSTCFQFTPERDEFDIDDKPPGYRWFELHDNGEFD 242

Query: 256 TEVHRLAD 263
           T+V  L D
Sbjct: 243 TDVTWLGD 250


>UniRef50_Q1Q887 Metallophosphoesterase n=2 Tax=Psychrobacter RepID=Q1Q887_PSYCK
          Length = 279

 Score =  134 bits (338), Expect = 3e-30,   Method: Compositional matrix adjust.
 Identities = 87/267 (32%), Positives = 131/267 (49%), Gaps = 19/267 (7%)

Query: 12  EARVRILQITDTHLF------AQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDL 65
           + +V +LQITD HL       A +  + + V  + S++A+++     +   DLI+ TGDL
Sbjct: 13  DGQVNVLQITDLHLSSHVPASADETSSEVAVCQY-SFEAIIKQALSKEIRCDLIIVTGDL 71

Query: 66  AQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSAL---QDAGISPA-------KR 115
                 A Y H    +     P   + GNHD    M   L   Q   I+ A       + 
Sbjct: 72  VNKVEPAIYDHIFTVLKETGIPFACIAGNHDVTDEMGEDLPFYQRTLIARACDPRLLSRH 131

Query: 116 VFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWL 175
           +   E WQ+LLLDS + G   GE++   ++W+  +LA    +  L+ LHHH LP    W+
Sbjct: 132 LIESEHWQLLLLDSSITGKVEGEITATDIDWVREQLASCA-KPALIALHHHVLPVDSEWI 190

Query: 176 DQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFT 235
           D H   NA E    +  F ++  ++ GH HQE    + G  + +TPSTC QFKP   NF 
Sbjct: 191 DSHMAENAEEFWQHITPFENLSVIINGHTHQEQTRHYQGVTVYSTPSTCYQFKPFEDNFA 250

Query: 236 LD-TIAPGWRTLELHADGTLTTEVHRL 261
            D  + PG+R L+L  +G + + V RL
Sbjct: 251 YDKNMRPGYRWLQLANNGKVASWVERL 277


>UniRef50_Q2BR54 Metallophosphoesterase n=1 Tax=Neptuniibacter caesariensis
           RepID=Q2BR54_9GAMM
          Length = 256

 Score =  126 bits (316), Expect = 1e-27,   Method: Compositional matrix adjust.
 Identities = 82/260 (31%), Positives = 131/260 (50%), Gaps = 13/260 (5%)

Query: 9   LAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQD 68
           +A  A + +LQ++D HL  +    L GVN  + +Q VL  I       D ++ TGDL   
Sbjct: 1   MADTAPILLLQVSDMHLQQEPDMLLKGVNVEQRFQQVLVEIE--SQSADALLLTGDLTH- 57

Query: 69  QSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLD 128
            +  AY+     +     P  W+PGNHD    M    +  G   A+RV     W+++ LD
Sbjct: 58  HAPRAYERLVSYVDCLPYPAYWIPGNHDLPEEM---ARFTGTELAQRVKTFGGWKLIFLD 114

Query: 129 SQVF--GVPHGELSEFQLEWLERKLAD-APERHTLLLLHHHPLPAGCSWLDQHSLRNAGE 185
           S     G   G LSE +L +L+ +L+  A ++H LL+LHHHP+P    W D+  L NA +
Sbjct: 115 SSSNPDGKGSGSLSETELSFLKAELSQTAADQHVLLVLHHHPVPVQSRWQDEICLANAEQ 174

Query: 186 LDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDT----IAP 241
              ++  +P VK ++ GH+HQ  +L     +L + P+T  QFK    +  ++       P
Sbjct: 175 FWQIVDLYPQVKGVIFGHVHQSWELQRGDIQLFSVPATAAQFKAQTDSSEVENDPKLAGP 234

Query: 242 GWRTLELHADGTLTTEVHRL 261
            +   +LH+ G ++ +V RL
Sbjct: 235 AYGRYQLHSCGKISQQVIRL 254


>UniRef50_A5WBU9 Calcineurin phosphoesterase C-terminal domain protein n=1
           Tax=Psychrobacter sp. PRwf-1 RepID=A5WBU9_PSYWF
          Length = 340

 Score =  125 bits (314), Expect = 1e-27,   Method: Compositional matrix adjust.
 Identities = 82/249 (32%), Positives = 121/249 (48%), Gaps = 12/249 (4%)

Query: 27  AQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRA 86
           A  H     ++ + S++A L          DLIV TGDL  +     YQH  + +     
Sbjct: 91  AINHSVTPVIHNYASFEACLTQALSEDVRCDLIVVTGDLVSEIHPQLYQHLYQRLHQSGI 150

Query: 87  PCVWLPGNHDFQPAMYSAL--QDAGISP--------AKRVFIGEQWQILLLDSQVFGVPH 136
           P   + GNHD    +   L  +     P        ++       W+IL ++S V G   
Sbjct: 151 PFACIAGNHDVTDEIGKDLPFEQRSFEPHEPDSRLLSRYSMKLNGWEILFINSSVPGQIF 210

Query: 137 GELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHV 196
           G +    L WL +KLA++     ++ +HHH LP   +W+D H  ++A E    +A F  +
Sbjct: 211 GRIGNKNLYWLSQKLANS-HHPVIIAMHHHLLPMHSAWIDAHITQDATEFWQTVAPFNAL 269

Query: 197 KYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA-PGWRTLELHADGTLT 255
           K ++ GH+HQ     + G +L +TPST  QFKP C +FTLD  A PG+R L L A+GTL 
Sbjct: 270 KAVVGGHVHQSSTRSYQGVQLYSTPSTGYQFKPGCDDFTLDDEAKPGYRWLSLKANGTLQ 329

Query: 256 TEVHRLADT 264
           + V RL D 
Sbjct: 330 SWVVRLEDN 338


>UniRef50_Q1QUF7 Metallophosphoesterase n=1 Tax=Chromohalobacter salexigens DSM 3043
           RepID=Q1QUF7_CHRSD
          Length = 244

 Score =  122 bits (307), Expect = 1e-26,   Method: Compositional matrix adjust.
 Identities = 87/252 (34%), Positives = 133/252 (52%), Gaps = 15/252 (5%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +R++QI+D HL A   EA   +  +  +Q      R  Q   D+++ TGD++QD+S AAY
Sbjct: 1   MRLVQISDCHLCANP-EARSRIG-YPLHQLRAVVARARQLRPDIVLVTGDISQDESPAAY 58

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
           +H  E  ++F  P  W+ GNHD    M      A + P        +W++LLLDS+V G 
Sbjct: 59  RHAYEVFSAFECPWFWMTGNHDHPEFM------AELHPFHDELDLGEWRLLLLDSRVPGQ 112

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
             GEL +  L+ L  +L +  +R TLL +HH PL  G +W+D   L +   L   LA + 
Sbjct: 113 AAGELGQGPLQDLAARL-EEDDRPTLLAMHHPPLEIGSAWMDALGLADREALWQTLAAYG 171

Query: 195 HVKYLLCGHIHQELDLDWNGRR----LLATPSTCVQFKPHCSNFTLDTIA-PGWRTLELH 249
            V+ +LCGHIHQ         +    +   P+T  QF P  ++F LD  + PG+R ++L 
Sbjct: 172 QVRAILCGHIHQAFAARHASSQGEIAVYGCPATADQFLPRQADFALDEASRPGFRVIDLE 231

Query: 250 ADGTLTTEVHRL 261
            +  L+T V R+
Sbjct: 232 GE-RLSTWVERV 242


>UniRef50_Q7NZT6 3',5'-cyclic-nucleotide phosphodiesterase n=1 Tax=Chromobacterium
           violaceum RepID=Q7NZT6_CHRVO
          Length = 244

 Score =  121 bits (303), Expect = 3e-26,   Method: Compositional matrix adjust.
 Identities = 83/245 (33%), Positives = 127/245 (51%), Gaps = 4/245 (1%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +RI Q+TD HLFA +   LLG +T  +   VL A+R  +   + ++ TGD++QD+S A+Y
Sbjct: 1   MRIAQLTDLHLFADRQGRLLGRDTHAALDGVLAALRTVE-GVEAVLLTGDVSQDESEASY 59

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQD-AGISPAKRVFIGEQWQILLLDSQVFG 133
              AE +A+   P  W+ GNHD + AM       A + P + + +G  W  + +DS V G
Sbjct: 60  HLAAEALAALGVPVHWIAGNHDDRAAMTRVFAGYAFLRPLETLALG-GWTFIGVDSCVAG 118

Query: 134 VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKF 193
              G LS+  L+ L R L +A +    ++LHHHPL  G   LD   L  A     + A  
Sbjct: 119 QDGGRLSDAGLDRLRRLLDEAGDGPAAVVLHHHPLAVGTPLLDDCMLAPASPFWRIAAAS 178

Query: 194 PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGT 253
             +K  +CGH+H E  + + G+ L   P+TC Q++    +  +D    G+R  +   DG 
Sbjct: 179 AALKLAICGHVHGEHSIAYRGKMLEVGPATCFQWRRDACDIEIDD-RHGYRLFDFDGDGY 237

Query: 254 LTTEV 258
           L   V
Sbjct: 238 LVRTV 242


>UniRef50_D2U008 3',5'-cyclic-nucleotide phosphodiesterase n=1 Tax=Arsenophonus
           nasoniae RepID=D2U008_9ENTR
          Length = 242

 Score =  120 bits (301), Expect = 5e-26,   Method: Compositional matrix adjust.
 Identities = 63/238 (26%), Positives = 124/238 (52%), Gaps = 4/238 (1%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++I+Q+TD HLF+ + + L GV T++S   +++ I  ++ ++D I+ TGD++QD++  +Y
Sbjct: 1   MKIIQLTDLHLFSDRTQKLFGVVTYDSLNKIIDHILINEGDYDAIILTGDISQDETIESY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
           Q   E +     P  ++ GNHD++  +         +P + + I   W  + +D+  +G 
Sbjct: 61  QLANEMLIRLNKPIHYIHGNHDYKSNLDLIFNIH--NPIENLSI-PYWDFISVDTVEYGK 117

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
             G +S+ +   L++K++++ E +  L++HHH L  G   +D   L N  +L   +    
Sbjct: 118 DSGFISDKEFRLLKKKISESKENNIALVMHHHCLKLGTPLIDDCMLLNNNQLLRFIDGEN 177

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADG 252
            +K ++CGH H    L  N   L   P+ C Q+K      +++ I+ G+R      + 
Sbjct: 178 KIKLIMCGHAHGNYKLKHNNSTLEVCPAVCFQWKKGTETPSIENIS-GYRKFSFFKEN 234


>UniRef50_A1ZTZ2 Metallophosphoesterase n=1 Tax=Microscilla marina ATCC 23134
           RepID=A1ZTZ2_9SPHI
          Length = 251

 Score =  117 bits (293), Expect = 5e-25,   Method: Compositional matrix adjust.
 Identities = 75/243 (30%), Positives = 120/243 (49%), Gaps = 16/243 (6%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +R   ++D HL+  K       + ++S+  V++ ++  +   D I+ TGD+A  Q   +Y
Sbjct: 4   LRFAHLSDLHLYKYKDFMYHEHHPYQSFCNVVDLLK-QEDTLDFILITGDIAAKQEKESY 62

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPA-----KRVFIGEQWQILLLDS 129
            H  E +A    P  WLPGNHD      SA+    I+P        VF  +  + +LLDS
Sbjct: 63  FHVDELLAPLGTPYYWLPGNHD------SAVLMKRIAPKVQVQNTNVFETKGTRFILLDS 116

Query: 130 ---QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGEL 186
              Q   V  G L + +L +LE+ LA+A    T++ LHH  L    SW +   + N  + 
Sbjct: 117 TDRQEKAVA-GFLPDDELRFLEKSLAEATNTSTIIALHHQLLATPGSWTNNLGVTNKNDF 175

Query: 187 DTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTL 246
             ++   P V+ ++CGHIH        G +  + P+T  QF P+   F LD +APG++ L
Sbjct: 176 YKIIDACPQVQAVICGHIHHAHAWQRKGVQYFSAPATSYQFNPYAPEFALDELAPGYQVL 235

Query: 247 ELH 249
            +H
Sbjct: 236 SIH 238


>UniRef50_Q47WJ3 Cyclic AMP phosphodiesterase n=1 Tax=Colwellia psychrerythraea 34H
           RepID=Q47WJ3_COLP3
          Length = 263

 Score =  114 bits (286), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 82/258 (31%), Positives = 127/258 (49%), Gaps = 19/258 (7%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +   QITD+HLF+       G N   + + VL +I  +      I+ TGDL QD +  +Y
Sbjct: 14  ITFAQITDSHLFSSVDGLHHGHNVLANLKKVLLSICDNP-SIKYIIFTGDLTQDHTEQSY 72

Query: 75  QHFAEGI--ASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVF 132
           Q+F + +       P  +L GNHD +P +      A    A +      WQ+ L+DS+  
Sbjct: 73  QNFVDCVLECHITVPIYYLAGNHD-EPKLLDKYFSASPFQADKEINLSHWQVQLVDSKS- 130

Query: 133 GVPHGELSEFQLEWLERKLADAPERHT--LLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
             P G + E  L     KL DA +++   LL++HHHP+  G  ++D+H L+N      V+
Sbjct: 131 ATPAGYVGEQAL----VKLKDAIQKNKNQLLMMHHHPIDVG-YFIDKHGLQNKDAFWQVI 185

Query: 191 AKFPHVKYLLCGHIHQELDLD------WNGRRLLAT-PSTCVQFKPHCSNFTLDTIAPGW 243
             + ++K + CGH+H ++ L        N   +L T P+T +QF P        +  PG+
Sbjct: 186 NSYDNIKAIACGHVHGDMTLTNAITSPINEPVVLYTCPATSIQFDPTVDGVAALSKGPGY 245

Query: 244 RTLELHADGTLTTEVHRL 261
           R   L+ADG L TEV  L
Sbjct: 246 RLFSLYADGQLNTEVVML 263


>UniRef50_A7BW21 Cyclic AMP phosphodiesterase n=1 Tax=Beggiatoa sp. PS
           RepID=A7BW21_9GAMM
          Length = 248

 Score =  113 bits (282), Expect = 7e-24,   Method: Compositional matrix adjust.
 Identities = 79/237 (33%), Positives = 121/237 (51%), Gaps = 15/237 (6%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS-AAYQ 75
           I Q+TDTH+    +    G+     +  VL A+   + + DL+V +GDLA  +    AY 
Sbjct: 8   IAQVTDTHI-GPMNIKYRGIEPRRQFLDVLRALT--KMKPDLLVLSGDLAAVEGEPEAYA 64

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSA--LQDAGISPAKRVF--IGEQWQILLLDSQV 131
              + +     P + + GNHD    M +A  LQ+  IS     F    +  ++L LDS  
Sbjct: 65  WIRDVLVKLPYPYLVMAGNHDHVVRMNNAFQLQETDISQGMLFFSRTIKDKRLLFLDSSP 124

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLD-QHSLRNAGELDTVL 190
           +      +++ QLEWL+ +L D   +  LL +HH PL  GCS++D  H L+N  E+  VL
Sbjct: 125 Y-----RIAKQQLEWLKEELNDY-HKQVLLFVHHPPLRCGCSFMDDHHGLQNGEEVWQVL 178

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLE 247
            +FP V+++ CGH H E  +  +G+ +  TPST  Q       F +D   PGWR +E
Sbjct: 179 EQFPQVQHIFCGHYHTEKTIIQSGKSVHLTPSTVFQINAENPKFAIDHTNPGWRMIE 235


>UniRef50_B3Q6B8 Metallophosphoesterase n=8 Tax=Bradyrhizobiaceae RepID=B3Q6B8_RHOPT
          Length = 284

 Score =  110 bits (276), Expect = 4e-23,   Method: Compositional matrix adjust.
 Identities = 70/214 (32%), Positives = 106/214 (49%), Gaps = 9/214 (4%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQ---AVLEAIRPHQHEFDLIVATGDLAQDQSS 71
           + I QI+D H+ A    A   V+T  +     A L A+ P  H   ++V +GDL    S+
Sbjct: 14  ILIAQISDLHIKAPGELAYGKVDTAAALTRCVAALNALAPRPH---VVVISGDLVDSPSA 70

Query: 72  AAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGI---SPAKRVFIGEQWQILLLD 128
             Y H    +A  + P V +PGNHD +  M +A          P  +++  +   I+LLD
Sbjct: 71  EEYAHLERLLAPLQIPFVAVPGNHDSRELMRTAFAQPTFPAEGPLNQLYPVDGIDIVLLD 130

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           S V G PHGEL    L+WLE  L+ +  R  LL LHH P   G   +D+ +LRNA E   
Sbjct: 131 SNVHGQPHGELEAGTLQWLEAVLSSSDHRPALLFLHHPPFATGIWHMDRQNLRNAAEFAL 190

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPS 222
           ++ ++P V+ +  GH+H+     + G      P+
Sbjct: 191 LVERYPWVRLVAAGHVHRATVTGFAGTVATICPA 224


>UniRef50_Q4JN56 Predicted 3',5'-cyclic-nucleotide phosphodiesterase n=1
           Tax=uncultured bacterium BAC13K9BAC RepID=Q4JN56_9BACT
          Length = 248

 Score =  109 bits (273), Expect = 8e-23,   Method: Compositional matrix adjust.
 Identities = 68/250 (27%), Positives = 118/250 (47%), Gaps = 5/250 (2%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + ++QITD H+             +++    L+ I  H      +V TGDL+ D +  +Y
Sbjct: 1   MEMIQITDLHITKDIENIKNDCKPYQTLSTTLKHIEHHHSNVKDVVITGDLSNDYTRESY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
                 +  +++    LPGNHD +    + + D  I+         +  +   D+ V G 
Sbjct: 61  MIIRNLLKKYQSTFYILPGNHD-KLEHINTICDEQITTNSIDLSMSKTLVYNFDTHVPGK 119

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHP-LPAGCSWLDQHSLRNAGELDTVLAKF 193
            +G L + Q+  L +KL    E   +++  HHP +  G  W+D+H   N+ EL  ++   
Sbjct: 120 TNGHLKKKQINELNKKLCINKEVDKVIIFTHHPIIKIGSEWIDEHISENSEELIQLMLSH 179

Query: 194 PHVKY-LLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDT-IAPGWRTLELHAD 251
              ++ +  GH+HQE +   N      TPSTC QFK     F L+T ++ G+R + LH D
Sbjct: 180 TDKEFKIFSGHVHQEFNCIKNNIEFFTTPSTCYQFKNQSEIFALETNLSYGYRVITLH-D 238

Query: 252 GTLTTEVHRL 261
            ++ T+V R+
Sbjct: 239 NSIRTKVLRI 248


>UniRef50_A4C954 Cyclic 3',5'-adenosine monophosphate phosphodiesterase n=2
           Tax=Alteromonadales RepID=A4C954_9GAMM
          Length = 263

 Score =  109 bits (272), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 83/257 (32%), Positives = 133/257 (51%), Gaps = 13/257 (5%)

Query: 12  EARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
           ++++R   I+D HLFA+ +E   GVN  +S + VL  +   +   D ++  GDL QD S 
Sbjct: 12  KSQLRFAHISDCHLFAEVNECYFGVNCCDSLRLVLTDLA--EQTLDFVIFGGDLTQDHSL 69

Query: 72  AAYQHFAEGIASFRAPC--VWLPGNHD----FQPAMYSALQDAGISPAKRVFIGEQWQIL 125
           A+YQ FA+ +   + PC  +WLPGNHD    +Q A +S L    IS AK V       + 
Sbjct: 70  ASYQLFAQLVNEAQLPCPVLWLPGNHDELDCYQQA-FSMLPSHVISRAKWV-QSPNLTVA 127

Query: 126 LLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGE 185
           L++S+    P G +    L  L  K+  A E++ ++  HHHP  A   +LD+H L N   
Sbjct: 128 LVNSK-GPTPAGWVEPAHLTELVCKIKTAAEKN-VVFCHHHP-KAIAGYLDKHILENGEW 184

Query: 186 LDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRT 245
             T LA+   V  +  GH+H +         + ATP+T +QF  + + +  + +  G+R 
Sbjct: 185 FLTQLAQTEQVTTVFHGHVHNDYLQQHGELSIYATPATSIQFVKNSATWQQEDLGAGYRI 244

Query: 246 LELHADGTLTTEVHRLA 262
           +  +  G +++EV  LA
Sbjct: 245 IHSNQLGEISSEVVWLA 261


>UniRef50_B4RZD1 3,5-cyclic-nucleotide phosphodiesterase n=2 Tax=Alteromonas
           macleodii RepID=B4RZD1_ALTMD
          Length = 267

 Score =  108 bits (271), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 74/267 (27%), Positives = 133/267 (49%), Gaps = 23/267 (8%)

Query: 15  VRILQITDTHLFAQKHE-ALLGVNTWESYQAVLEAIRPHQHEFD----------LIVATG 63
           ++++Q++D HL   K+E    G+  ++S +  L     H  +F+           ++ TG
Sbjct: 2   IKLIQLSDCHLLKDKNETGYAGIAPYDSLERTLLHAVNHAEQFEANNSSMAPSCFMLITG 61

Query: 64  DLAQDQSSAAYQHFAEGIASF--RAPCVW--LPGNHDFQPAMYSALQDAGISPAKRVFIG 119
           D++ D +  +YQHF   +  +  RA   W  L GNHD      + L D  ++ +      
Sbjct: 62  DISGDNTPESYQHFIALMDKYVDRANIAWFVLAGNHDNNAHFETYLGDKQLN-SDNPLTF 120

Query: 120 EQWQILLLDSQVFGVPH---GELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLD 176
           + W I  +D++     +   GE+   ++  L + +A  P+ + L+ LHHH LP+  SW+D
Sbjct: 121 QNWHIHGMDTRALDSTYTAAGEVKGGEIHDLTQAVAQLPDNNHLIALHHHILPSN-SWMD 179

Query: 177 QHSLRNAGELDTVLAKFPHVKYLLCGHIHQELD--LDWNGRRLLATPSTCVQFKPHCSNF 234
           +H L NA  L ++  ++  +K L+ GH+H  L   +  N       PSTC Q++   + F
Sbjct: 180 KHFLANAEALVSLTEQYAQIKALIHGHVHSPLRQLIGENSTPSYGCPSTCWQWEMQLA-F 238

Query: 235 TLDTIAPGWRTLELHADGTLTTEVHRL 261
            +   APG++ +ELH DG +   + R+
Sbjct: 239 GVSNDAPGYQVIELHEDGVVDVSIERV 265


>UniRef50_B1KBF2 Metallophosphoesterase n=5 Tax=Proteobacteria RepID=B1KBF2_BURCC
          Length = 266

 Score =  108 bits (271), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 68/218 (31%), Positives = 112/218 (51%), Gaps = 10/218 (4%)

Query: 17  ILQITDTHLFAQKHEALL--GVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           I Q++D H+  + H  L    V++   + A ++++   + E DL+V +GDL  + +   Y
Sbjct: 4   IAQLSDIHV--RPHGVLYQDAVDSNAMFSAAVDSLNRIRPEPDLVVISGDLTDEGTEGEY 61

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVF-----IGEQWQILLLDS 129
           +   E +   R P V LPGNHD +  + +A  D    P +        +GE  +++ LD+
Sbjct: 62  RKLRELLVELRRPFVVLPGNHDDRGNLRAAFPDHAWLPDEGALSFALDVGE-LRLVALDT 120

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
            V G+ HGEL    L WL+ +LA+   R  ++++HH P   G  +LD + LRNA     V
Sbjct: 121 SVPGLHHGELGAETLAWLDTELAEHRNRTVVIVMHHPPFMTGIPYLDIYGLRNAEAFAAV 180

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQF 227
           LA+  +V  +L GH+H+ +        +L  PST  Q 
Sbjct: 181 LARHDNVDRILAGHVHRSMQTRLGRVPVLTCPSTITQI 218


>UniRef50_Q3IG69 Cyclic 3',5'-adenosine monophosphate phosphodiesterase n=1
           Tax=Pseudoalteromonas haloplanktis TAC125
           RepID=Q3IG69_PSEHT
          Length = 281

 Score =  107 bits (266), Expect = 6e-22,   Method: Compositional matrix adjust.
 Identities = 78/261 (29%), Positives = 120/261 (45%), Gaps = 27/261 (10%)

Query: 11  GEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQS 70
            +  +RI  +TD HLFA ++    GVNT   +Q  LE +   Q   D +V  GDL QD S
Sbjct: 11  NKPSLRIAHVTDCHLFADRNAEYFGVNTATYFQQALEHMALQQ--LDAVVFGGDLTQDHS 68

Query: 71  SAAYQHFAEGIA--SFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFI---------- 118
             +Y  F+E I+  +   P  WLPGNHD + A+   +    I  AKR+            
Sbjct: 69  VESYLLFSELISNSTLTCPVFWLPGNHD-EIALLEQISGGQIKAAKRLVANNLTNNLTNN 127

Query: 119 ---------GEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLP 169
                        ++LL++S+    P G ++   L  +   LA  P    L+  HH+PLP
Sbjct: 128 LTNNLTNNASTDIELLLINSKGL-TPAGWVTSEHLNEISDCLAQ-PVSKQLVFCHHNPLP 185

Query: 170 AGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKP 229
               +LD+H L N  +L   L    +V  L+ GH+H +    +    + ATP++ VQF  
Sbjct: 186 IN-GYLDKHMLENGPQLLNTLVNNGNVAALIHGHVHNDYTQCFRELDIYATPASSVQFTK 244

Query: 230 HCSNFTLDTIAPGWRTLELHA 250
           H   +      P +R L +++
Sbjct: 245 HSKAWQQQNNGPAYRMLYINS 265


>UniRef50_B3TB35 Putative calcineurin-like phosphoesterase n=1 Tax=uncultured marine
           microorganism HF4000_APKG8K5 RepID=B3TB35_9ZZZZ
          Length = 245

 Score =  105 bits (263), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 61/179 (34%), Positives = 95/179 (53%), Gaps = 9/179 (5%)

Query: 57  DLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISP---- 112
           D++VATGDL    S   Y +  E +A        +PGNHD + A+  A  D G  P    
Sbjct: 17  DIVVATGDLTYLGSPEEYAYLRELLAPLECSVFLIPGNHDGRGALREAFADQGYFPEPSG 76

Query: 113 AKRVFIG---EQW--QILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHP 167
             R F+    E +  +++ LD+ V G P G L E Q+ WL+  L ++P R T++L+HH P
Sbjct: 77  GDRDFLNYTVEDYPLRLIALDTVVPGKPGGWLDETQIAWLDECLGESPSRPTMILMHHPP 136

Query: 168 LPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQ 226
             +G + +D     N+  L  V+A+ P V+ ++CGH+H+ + L W+G  +   PS   Q
Sbjct: 137 YVSGIAHMDAMMCGNSDALGAVVARHPQVERIICGHLHRPVHLRWHGTVVCTAPSPGFQ 195


>UniRef50_B3YLU1 Cyclic 3',5'-adenosine monophosphate phosphodiesterase n=1
          Tax=Salmonella enterica subsp. enterica serovar
          Kentucky str. CVM29188 RepID=B3YLU1_SALET
          Length = 65

 Score =  105 bits (263), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 50/57 (87%), Positives = 53/57 (92%)

Query: 1  MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFD 57
          MESLLTLPLAGEARVRILQITDTHLFA+KHE LLGVNTWESYQAVLEAIR  Q++ D
Sbjct: 1  MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQAVLEAIRAQQYDLD 57


>UniRef50_Q1LDS0 Metallophosphoesterase n=10 Tax=Proteobacteria RepID=Q1LDS0_RALME
          Length = 290

 Score =  105 bits (262), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 58/218 (26%), Positives = 103/218 (47%), Gaps = 8/218 (3%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           + Q+TD H+ A    +   V+T  + +  ++ +     + D+++ TGDL    S + Y+ 
Sbjct: 17  VAQLTDLHIKAGGKLSYRRVDTAGALRTAIDTLLAAPQQPDIVIVTGDLVDFGSESEYRF 76

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQD--------AGISPAKRVFIGEQWQILLLD 128
             + +     P   LPGNHD +P++ +   D         G +P          +++  D
Sbjct: 77  LRDLLQPLPMPVRLLPGNHDHRPSLRAVFADHDYLFANGDGDAPVHYAIDAGPLRLVGFD 136

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
             V G P G   +  L WL+  LA AP++ TL++LHH P   G   +D   L NA   + 
Sbjct: 137 CTVPGKPGGRAEDAGLAWLDATLAAAPKQPTLVMLHHPPFHTGIGHMDDQGLENAPAFEA 196

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQ 226
           ++A+ P V+ ++CGH+H+ +   + G   +  P    Q
Sbjct: 197 IIARHPQVERVVCGHLHRHITRRFGGTIAMTAPGPAHQ 234


>UniRef50_C9RR52 Metallophosphoesterase n=1 Tax=Fibrobacter succinogenes subsp.
           succinogenes S85 RepID=C9RR52_FIBSS
          Length = 249

 Score =  105 bits (261), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 69/242 (28%), Positives = 115/242 (47%), Gaps = 23/242 (9%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++I QI+D H+       +  ++  +++     +      + DL+V +GDLA + S+ AY
Sbjct: 6   LKIGQISDAHI-GDDDRLVQDIDVRKNFLTAYNS--ESMKDLDLLVLSGDLADNASTDAY 62

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQW--------QILL 126
              A  I   + P   +PGNHD    M             +V  G+ +         I  
Sbjct: 63  SFIAGVIKDSKVPVCIIPGNHDNLEVMEKVFD-----LKDKVHNGKCYYRYDLDGRSIFF 117

Query: 127 LDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLD-QHSLRNAGE 185
           LDS       G +S  QL WLE++ A   +   LL LHH P   G  ++D ++S++N  E
Sbjct: 118 LDS-----ADGTVSSDQLSWLEQETAKI-DGEVLLFLHHPPCLCGHKFMDLRYSMKNIAE 171

Query: 186 LDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRT 245
           +   L+K  ++K++  GH H E+ +    + +  TPST +Q  P+ + F L + AP WR 
Sbjct: 172 VQATLSKIKNLKHIFVGHYHSEMTIQLEDKTVYVTPSTQMQIDPNITVFCLSSAAPRWRL 231

Query: 246 LE 247
           +E
Sbjct: 232 IE 233


>UniRef50_A6D2K7 Ser/Thr protein phosphatase family protein n=1 Tax=Vibrio shilonii
           AK1 RepID=A6D2K7_9VIBR
          Length = 271

 Score =  104 bits (260), Expect = 3e-21,   Method: Compositional matrix adjust.
 Identities = 80/245 (32%), Positives = 112/245 (45%), Gaps = 9/245 (3%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           I Q+TD H+      A   V+T    Q  ++ I       D +V TGDL    +   YQ 
Sbjct: 3   IAQLTDLHIKQDGKPAYRKVDTLRCLQNAVQHINHLNPRPDYVVITGDLGDFGTEQEYQI 62

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGI--SPAKRVFIGEQ-WQILL-LDSQVF 132
             + +   + P   +PGNHD +  +   LQ       P    F+ EQ  Q+LL LDS V 
Sbjct: 63  IRQELEKLQLPLRVVPGNHDHRDNLRVGLQQLVDFDHPEFCNFVVEQDEQVLLGLDSSVI 122

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
           G P+G LS   LEWL+ +LA    +  L+ LHH P+  G   +D  +L NA  L  VL++
Sbjct: 123 GKPYGFLSSQTLEWLQSQLARLSNKSVLIFLHHPPMHVGLGHMDVQNLTNADSLYEVLSQ 182

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADG 252
           F +V+ L  GH+H+ +   W    +   PS       H     LD  AP   +LE  A  
Sbjct: 183 FDNVRGLCAGHLHRPITATWRSIPVWVGPSHS-----HSVTLDLDPNAPSSFSLEPRAIQ 237

Query: 253 TLTTE 257
            L  E
Sbjct: 238 LLKFE 242


>UniRef50_A2C6L9 Serine/threonine specific protein phosphatase n=2
           Tax=Prochlorococcus marinus RepID=A2C6L9_PROM3
          Length = 263

 Score =  104 bits (259), Expect = 4e-21,   Method: Compositional matrix adjust.
 Identities = 83/259 (32%), Positives = 127/259 (49%), Gaps = 22/259 (8%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +R++Q++D HL A  H  +   N   ++Q  L+  +   H  DL++ TGDL  D+S   Y
Sbjct: 1   MRLVQLSDPHLVAFNHRLVRDQNPLLNFQCALQ--QGMSHSPDLLLITGDLCHDESWCGY 58

Query: 75  QHFAEGIASFRAPCV---WLPGNHDFQPAMYSAL-QDAGISPAKRVFIGEQWQILLLDSQ 130
               + + +  +P +    LPGNHD    + +AL + A  +PA     G +  ++LL S 
Sbjct: 59  VLLRDELQNL-SPSIKVAVLPGNHDNPLFIKAALGRHAFTAPADLNLDGVR--LILLSSH 115

Query: 131 VFGVPHGELSEFQLEWLERKLADAPE--RHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           V G   G+L E QL+WL+ +L+D  +  R  ++ +HH PLP G SWLD   L +   L  
Sbjct: 116 VSGRTAGQLGESQLQWLDSRLSDIEQSGRPLVVAVHHPPLPIGSSWLDAIGLVDGEALIK 175

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNG----RR---LLATPSTCVQFKPHCSNFTLDTIAP 241
           +L     +  ++CGHIHQ     W G    R+   +L  PST   FK            P
Sbjct: 176 LLTPVDELCAVVCGHIHQH----WQGLFPERKDVLVLGCPSTLCSFKAVQPCLLGREDEP 231

Query: 242 GWRTLELHADGTLTTEVHR 260
           G R +EL   G    ++ R
Sbjct: 232 GGRLIELDESGNFFEKLLR 250


>UniRef50_A3RQT5 Icc protein n=4 Tax=Ralstonia solanacearum RepID=A3RQT5_RALSO
          Length = 263

 Score =  102 bits (254), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 63/239 (26%), Positives = 110/239 (46%), Gaps = 9/239 (3%)

Query: 19  QITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFA 78
           QITD HL A +   L+G  T+      ++AI  H    D+   TGD++QD+S  +Y+   
Sbjct: 21  QITDLHLLADRESELMGYCTYSMLSDTVDAILEHDIRPDVCFLTGDISQDESVESYELAR 80

Query: 79  EGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKR---VFIGEQWQILLLDSQVFGVP 135
             +     P  W+PGNHD +    +     G S + R     +   W  + LD+   G  
Sbjct: 81  SELERLGIPVFWIPGNHDERDGAEAVF---GASESIRRLTKLVTADWDFIYLDTCRQGAG 137

Query: 136 HGELSEFQLEWLERKL--ADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKF 193
            G L++   E    ++  +    ++  +++HHHP+P     LD + L +   L  +L + 
Sbjct: 138 EGYLNDQDFERFVSQVEASTGGGKNIAVVMHHHPVPTQTPLLDGYMLLDNERLLKMLDEH 197

Query: 194 PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADG 252
             VK ++CGH+H +  + +  + +   P+TC Q++   S    +    G+R  E    G
Sbjct: 198 QQVKLVICGHVHGDYRIRYGNQMIEMCPATCFQWEKGTSAMKTENWR-GFRVFEFSPSG 255


>UniRef50_A7IH99 Metallophosphoesterase n=2 Tax=Xanthobacteraceae RepID=A7IH99_XANP2
          Length = 276

 Score =  102 bits (253), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 69/229 (30%), Positives = 106/229 (46%), Gaps = 9/229 (3%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           I Q+TDTH+      A   V+T    +A +  I       D+++ TGDL      A Y  
Sbjct: 3   IAQLTDTHIRRPGTLAYGVVDTALYLEAAVAHILALAPRPDVVIVTGDLTDFDDPAEYAR 62

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQD-AGISPAKRV-FIGEQW--QILLLDSQVF 132
           F    A+   P + +PGNHD    + +A  + A      RV ++ E +  ++++LDS V+
Sbjct: 63  FRALTAALPMPLLPIPGNHDSSAGLLAAFPEIAARCDGGRVNYVVEDFPLRLVMLDSTVY 122

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
           G PHG+L E  L +L+R L   P R   +  HH P   G   +D  +L +A  L+ V   
Sbjct: 123 GCPHGQLGEEGLAFLDRALGATPGRPAFVCAHHPPFLTGIRHMDVQNLSDAAGLEEVFGH 182

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAP 241
           +P V    CGH+H+ +   + G      P+       H  +  LD  AP
Sbjct: 183 WPQVLGFTCGHVHRAVTTTFAGIAATIGPAPA-----HAVSLALDPQAP 226


>UniRef50_Q162P5 Ser/Thr protein phosphatase family protein, putative n=7
           Tax=Rhodobacterales RepID=Q162P5_ROSDO
          Length = 267

 Score =  100 bits (250), Expect = 4e-20,   Method: Compositional matrix adjust.
 Identities = 68/220 (30%), Positives = 99/220 (45%), Gaps = 5/220 (2%)

Query: 17  ILQITDTHLFAQK---HEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
           IL ITDTH+  +       L   +  E   A + +IR      D ++ +GDL+ D S+ +
Sbjct: 4   ILHITDTHIVPEGALVSGRLDTADALERLVARINSIRDQIGAVDAVLVSGDLSDDGSAES 63

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSAL--QDAGISPAKRVFIGEQWQILLLDSQV 131
           Y+ F   +A    P   +PGNHD +  + +A   Q A   P   V       ++ LD+ V
Sbjct: 64  YKRFKRLVAPLGLPIHVIPGNHDGRATLRAAFAEQFAPTGPLNWVRSIGDLHLIGLDTLV 123

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
            G   G L+   L +L   L+ A     LL LHH P   G  ++D   L N   L  ++A
Sbjct: 124 EGQGGGRLAPESLSFLSDALSQAEGAPVLLALHHQPFLCGIGFMDAIGLSNKNALSEIVA 183

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHC 231
            +     LLCGHIH  +  D  G   ++ PS C  F   C
Sbjct: 184 GYQGPLRLLCGHIHSTMISDVGGHIAISCPSPCSSFAFDC 223


>UniRef50_P05675 Uncharacterized protein syc0937_d n=2 Tax=Synechococcus elongatus
           RepID=Y937_SYNP6
          Length = 255

 Score = 99.4 bits (246), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 83/255 (32%), Positives = 128/255 (50%), Gaps = 18/255 (7%)

Query: 9   LAGEA-RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQ 67
            AG+A  + I QITD HL      AL G  T     AV   ++  Q   DL++ +GDL++
Sbjct: 5   FAGDAMTLSIAQITDLHLLVDPQAALRGCVTTPRAAAVFGNLK--QRSPDLLLLSGDLSE 62

Query: 68  DQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISP--AKRVFIGEQWQIL 125
           D S A+Y+   + +     P + + GNHD QP   + +   G SP   + V+  + W+I+
Sbjct: 63  DGSPASYERLRDWVEELGCPAIAIAGNHD-QPERLTEI--CGRSPFMGEPVYSIQGWRII 119

Query: 126 LLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGE 185
            LDS       G L   QL+WL+++L +     TLL+LHH P+  G + +D   L++  E
Sbjct: 120 ALDSYQPKRIDGRLRGDQLDWLDQRLGED-SSPTLLMLHHPPVLIGVTKMDAIGLKDGPE 178

Query: 186 LDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQF-KPHCSNFTLDTIAPGWR 244
              V+A    V+ +L GH HQ           L  P+T +QF +P         +  GWR
Sbjct: 179 FLEVIAHHQQVRLVLSGHAHQAFIQGRGLTTFLGCPATAMQFDQPE--------LPAGWR 230

Query: 245 TLELHADGTLTTEVH 259
           +LEL  DG+  +++H
Sbjct: 231 SLELEPDGSWRSQIH 245


>UniRef50_Q3AIR5 Possible ICC (3',5'-cyclic-nucleotide phosphodiesterase) protein
           n=4 Tax=Chroococcales RepID=Q3AIR5_SYNSC
          Length = 253

 Score = 99.4 bits (246), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 85/258 (32%), Positives = 120/258 (46%), Gaps = 21/258 (8%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLE---AIRPHQHEFDLIVATGDLAQDQSS 71
           +RILQ++D HL A     + G      ++  L+   A+ P     DL++ TGDL QD+S 
Sbjct: 1   MRILQLSDPHLVAADQGLVRGRPALAHFERALQLGGALNP-----DLVLVTGDLCQDESW 55

Query: 72  AAYQHFAEGIAS-FRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQ 130
             Y      ++   R     LPGNHD  P +  A+     + A    + +  ++LLL S 
Sbjct: 56  GGYARLRRALSQHVRCSVALLPGNHD-HPLLLDAVLGRRWTTAPADLLVQGVRVLLLSSH 114

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLL---LHHHPLPAGCSWLDQHSLRNAGELD 187
             G   G L   QL+WLE++L    ER  L L   LHH P+  G + +D   L +   L+
Sbjct: 115 QVGSAAGALGSLQLQWLEQRL-RCSERLDLPLVVALHHPPIAIGDAGMDAIRLLDQACLE 173

Query: 188 TVLAKFPHVKYLLCGHIHQELDLDWNGR---RLLATPSTCVQFKP--HCSNFTLDTIAPG 242
            +L     ++ +L GHIHQ     W+ R    LL  PST   FK    C     D   PG
Sbjct: 174 ALLRPHRALRAVLFGHIHQHWQGSWSTRPDVLLLGCPSTLCSFKAVQPCPLGRADD--PG 231

Query: 243 WRTLELHADGTLTTEVHR 260
            R +EL ADG +   V R
Sbjct: 232 GRLVELTADGAIQHRVLR 249


>UniRef50_Q15YS5 Metallophosphoesterase n=1 Tax=Pseudoalteromonas atlantica T6c
           RepID=Q15YS5_PSEA6
          Length = 250

 Score = 97.8 bits (242), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 77/256 (30%), Positives = 134/256 (52%), Gaps = 19/256 (7%)

Query: 16  RILQITDTHLFAQK-HEALLGVNTWESYQAVLEAI---RPHQHEFDLIVATGDLAQDQSS 71
           ++ QI+D HLFA K H     +N + + QAVL+ +    P     D+++ +GD++ +  +
Sbjct: 4   KVAQISDCHLFADKRHAGYQNINPYTTLQAVLKNVGLCHP-----DMVIVSGDVSAENDA 58

Query: 72  ----AAYQHFAE--GIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQIL 125
               A+YQ F++    +   AP + +PGNHD   A+ + L      P      G  W++ 
Sbjct: 59  VKGLASYQLFSQLWQQSKISAPLLVIPGNHDHLEALNNELNHLAGWPLS-TSAGPYWKVH 117

Query: 126 LLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGE 185
            L+++      GE+S  QL++L  ++   P++H LL++HHHP   G  W+D H  RN  E
Sbjct: 118 GLNTKTDD-SSGEISMRQLQYLNEQVNLHPQQHHLLVVHHHPYACG-GWMDNHPWRNRDE 175

Query: 186 LDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRT 245
               + + P +K ++ GHIHQ  +        ++ PSTC Q+  +   F+    APG+R 
Sbjct: 176 FIQNVEQQPQIKAVIYGHIHQASETRSQDCVFMSAPSTCWQWA-NSKEFSASGEAPGYRV 234

Query: 246 LELHADGTLTTEVHRL 261
           +EL  +G + + + R+
Sbjct: 235 IELADNGQVDSHIIRI 250


>UniRef50_B8J1S2 Metallophosphoesterase n=1 Tax=Desulfovibrio desulfuricans subsp.
           desulfuricans str. ATCC 27774 RepID=B8J1S2_DESDA
          Length = 276

 Score = 95.9 bits (237), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 77/264 (29%), Positives = 116/264 (43%), Gaps = 17/264 (6%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + ILQ++DTHL      +   V+T     A    ++    + D+IV +GDLA      AY
Sbjct: 1   MHILQLSDTHLRGDNSLSFRVVDTRRCLDAATAHLKTMAQKPDIIVLSGDLADSGDLNAY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAK--------RVFIGEQWQILL 126
               + ++    P   LPGNHD +  M   LQ  G  PA              ++ ++++
Sbjct: 61  HILYDALSPLGIPVYALPGNHDRRDRMRDVLQ--GWCPAAPEVSPHICYTVEMDELRLVM 118

Query: 127 LDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGEL 186
           +DS   G   G L      WL R LA  P+  TL+ +HH P   G   +D+    N G L
Sbjct: 119 VDSMHPGSHSGHLFPAVEGWLARTLAQRPDVQTLVFMHHPPFMTGMGAMDE-PFENQGAL 177

Query: 187 DTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTI---APGW 243
             +    P ++ L  GH+H+ +   W GR  +  PS  +Q     S    DT    APG+
Sbjct: 178 AAIAGDNPQIR-LCFGHMHRPIITQWQGRLCMTAPSAAMQIDLDLSPEGGDTFRMEAPGY 236

Query: 244 RTLELHADGTLTTEVHRL-ADTRF 266
             L  +  G L T V ++ +D  F
Sbjct: 237 -LLHHYEHGILNTHVCQIPSDVTF 259


>UniRef50_B6IT97 Phosphodiesterase, putative n=1 Tax=Rhodospirillum centenum SW
           RepID=B6IT97_RHOCS
          Length = 265

 Score = 94.0 bits (232), Expect = 5e-18,   Method: Compositional matrix adjust.
 Identities = 68/214 (31%), Positives = 105/214 (49%), Gaps = 7/214 (3%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           I Q+TD H+ A+   A   V+T ++    +  +       DL+V TGD+        Y  
Sbjct: 3   IAQLTDLHVTARGARAFGEVDTNDALARAVAHVAALPRRPDLVVVTGDVVNGPQPGEYAM 62

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQ--DAGISPAK---RVFIGEQWQILLLDSQV 131
            AE +A    P + +PGNHD +  + +AL+  D G+       R+      +IL LD+ V
Sbjct: 63  AAELLAGLGLPLLVIPGNHDDREELRTALRPLDPGLPDGPYLHRMMDTGPLRILALDTVV 122

Query: 132 FGVPHGELSEFQLEWLERKLADAP-ERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
            G P G L   +L W+  +LA+AP ER  L+L+HH P  +G   +D+ +   A  L  +L
Sbjct: 123 PGRPEGALDAPRLAWIADRLAEAPHERPLLVLMHHPPFVSGIGHMDRMNCAGADALAGLL 182

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTC 224
            +   V  LLCGH+H+ +   W G      P+T 
Sbjct: 183 -RGRTVAGLLCGHVHRPIAAHWRGIPCFCGPATA 215


>UniRef50_B6J9P9 3',5'-cyclic-nucleotide phosphodiesterase n=7 Tax=Coxiella burnetii
           RepID=B6J9P9_COXB1
          Length = 246

 Score = 93.6 bits (231), Expect = 7e-18,   Method: Compositional matrix adjust.
 Identities = 54/224 (24%), Positives = 106/224 (47%), Gaps = 5/224 (2%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIR-PHQHEFDLIVATGDLAQDQSSAA 73
           ++I Q++D HL ++  E   G   + +   V  AI    QH  D+I  TGD++ D +  +
Sbjct: 6   IKIAQVSDLHLTSENCETSRG--RYSNAMNVFSAISLSGQH--DMIFITGDISDDYTENS 61

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFG 133
           Y+   E +         +PGNHD    M   + +  +   + V     +  L +++ V G
Sbjct: 62  YKQLLEMLKKLTCRVFVIPGNHDDFNLMNKIIPEKYLFSPETVTSFNTFDFLFVNTVVNG 121

Query: 134 VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKF 193
             HG L+   L  L+  L ++  +   +++HH+P+P      D++ L N  +   ++  +
Sbjct: 122 EIHGLLTGQDLSLLQNHLENSGNKKKCMIMHHNPIPLNRKIYDKYMLLNYQDFLRIICLY 181

Query: 194 PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLD 237
            +VK ++ GH+H +  + +      + P+TC Q K   S+  ++
Sbjct: 182 DNVKLVIFGHVHNDYTISYRQTLFSSAPATCYQIKKFESDIIIE 225


>UniRef50_A9WNR5 Putative 3',5'-cyclic-nucleotide phosphodiesterase n=1
           Tax=Renibacterium salmoninarum ATCC 33209
           RepID=A9WNR5_RENSM
          Length = 309

 Score = 93.2 bits (230), Expect = 9e-18,   Method: Compositional matrix adjust.
 Identities = 70/208 (33%), Positives = 103/208 (49%), Gaps = 21/208 (10%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRP--HQHEFDLIVATGDLAQDQSSAAY 74
           IL ++DTH+ A+     L  N  ++ Q +LEA+R      E DL+V +GD++ D ++ +Y
Sbjct: 12  ILHLSDTHVLAKG----LHSNVVDTRQNLLEALRALVPVEELDLVVVSGDVSDDGTAESY 67

Query: 75  ---QHFAEGIASFR-APCVWLPGNHDFQPAMYSAL----------QDAGISPAKRVFIGE 120
              Q   E  AS R A  ++  GNHD +P  +  L          QD G  P     +  
Sbjct: 68  RMVQELVENFASHRGARAIYTMGNHDGRPGFWEVLGNGHPDSPAEQDGGQLPVYGSSVLG 127

Query: 121 QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL 180
            ++I+ LD+ V G  HG L   QL+WL  +L  A E  T+L+LHH P+       D   L
Sbjct: 128 GFRIISLDTSVPGRTHGYLDRGQLDWLTEELGSASEAGTVLVLHHPPVEPVTPLHDGIEL 187

Query: 181 RNAGELDTVLAKFPHVKYLLCGHIHQEL 208
           +N  +L  VL     V+ +L GH H  L
Sbjct: 188 QNPEDLLEVL-HGSDVRLILSGHYHHGL 214


>UniRef50_D1A354 Metallophosphoesterase n=1 Tax=Thermomonospora curvata DSM 43183
           RepID=D1A354_THECD
          Length = 270

 Score = 92.8 bits (229), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 69/235 (29%), Positives = 107/235 (45%), Gaps = 16/235 (6%)

Query: 17  ILQITDTHLFAQKHEALLG-VNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           I Q++D HL A     +        + ++ + ++       D +V TGDLA       Y+
Sbjct: 4   IAQLSDIHLAAGADGRVDDRSGPVRALRSAVSSLLALPQRPDCVVLTGDLADRGLPVEYE 63

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGIS--------PAKRVFIGEQWQILLL 127
                ++    P   LPGNHD + A+  A  D   +        P +        +++  
Sbjct: 64  RLRALLSPLPMPVFPLPGNHDDRAALREAFADRTAACAAPDPQAPFQYAVQVRGVRLVCC 123

Query: 128 DSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELD 187
           D+ V G  HGEL E +L+WL+  LA AP+  T++  HH P P G  +LD+  LR+A  L 
Sbjct: 124 DTTVPGESHGELDEERLQWLDAALAAAPDVPTVVATHHPPFPIGVRFLDEAGLRDAAALG 183

Query: 188 TVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPG 242
            VLA+ P V+ ++ GH+H+           +  PST  Q         LDT +PG
Sbjct: 184 AVLARHPQVERVISGHVHRAAVGRIGEITAVTCPSTYRQIY-------LDTTSPG 231


>UniRef50_A5CN72 Putative 3',5'-cyclic-nucleotide phosphodiesterase n=2
           Tax=Clavibacter michiganensis RepID=A5CN72_CLAM3
          Length = 301

 Score = 91.3 bits (225), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 79/270 (29%), Positives = 127/270 (47%), Gaps = 32/270 (11%)

Query: 15  VRILQITDTHLFAQK--HEALLGVNTWESYQAVL-EAIRPHQHEFDLIVATGDLAQDQSS 71
           +R++ ++DTHL      H+ +  V+T  + + VL EA R    E  L+V +GDL++D ++
Sbjct: 9   LRLVHLSDTHLLRDGGLHQGV--VDTGAALERVLVEADR--VPEVRLLVGSGDLSEDGTA 64

Query: 72  AAYQHFAEGI----ASFRAPCVWLPGNHDFQPAMYSALQD-------------AGISPAK 114
            +Y    E +    +S  A  V  PGNHD + A    L D             A + P  
Sbjct: 65  ESYALLRERLVPWTSSRGAALVLTPGNHDVRSAFRLVLGDGHGAPGTDDGRDPAAVPPVD 124

Query: 115 RVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSW 174
            V I + W+I  LD+ V G  +G L E QL+ L   LA   E  T+L+LHH P+PA  + 
Sbjct: 125 GVTIVDGWRIATLDTSVPGKGYGALREQQLDGLRELLATPAEHGTVLVLHHPPVPAPTTL 184

Query: 175 LDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPS----TCVQFKPH 230
            +  +L+    L  ++ +   V+ +L GH H  +     G  +L  P     T V  +P 
Sbjct: 185 HESLALQGPERLAEIV-RGSDVRVILSGHYHHHIVGSLAGVPVLVAPGVANETDVAAEPG 243

Query: 231 CSNFTLDTIAPGWRTLELHADGTLTTEVHR 260
                  +   G+  +++  DG +T+ V R
Sbjct: 244 TERIVRGS---GFLVVDVRPDGRVTSVVVR 270


>UniRef50_B9QUB7 Ser/Thr protein phosphatase family protein n=1 Tax=Labrenzia
           alexandrii DFL-11 RepID=B9QUB7_9RHOB
          Length = 278

 Score = 91.3 bits (225), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 63/215 (29%), Positives = 101/215 (46%), Gaps = 22/215 (10%)

Query: 19  QITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFA 78
           +++DT++ A++  A+L +N            RP     D +V TGDL        Y    
Sbjct: 21  RVSDTNMLAER--AILALNGLTP--------RP-----DAVVLTGDLTDKSDPREYALAR 65

Query: 79  EGIASFRAPCVWLPGNHDFQPAMYSALQD----AGISPAKRVFIGE--QWQILLLDSQVF 132
           + ++    P   +PGNHD    M   +       G    K  +  E    +++ LD+ + 
Sbjct: 66  QILSRLAMPVFMIPGNHDGSADMRREMSGFPGMDGDVDGKLCYTAEIGDVRLIALDTNIP 125

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
           G P+GEL   QL WL  +L+D   R TL+ LHH P  +G   +D   L +A  L  V+  
Sbjct: 126 GKPNGELGTPQLNWLSDRLSDD-NRPTLIALHHPPALSGIQHMDAIGLNDANALAEVIGP 184

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQF 227
             H++ LLCGH+H+ +  ++ G+ +   PST  Q 
Sbjct: 185 HKHIQRLLCGHLHRPIIAEFAGKIMTLAPSTGHQV 219


>UniRef50_D1U8L8 Metallophosphoesterase n=1 Tax=Desulfovibrio aespoeensis Aspo-2
           RepID=D1U8L8_9DELT
          Length = 282

 Score = 91.3 bits (225), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 61/218 (27%), Positives = 100/218 (45%), Gaps = 16/218 (7%)

Query: 17  ILQITDTHLFAQKHEALLGVNT---WESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
           I  I+D H+     +    V+T      + A L +I       D ++ TGD+        
Sbjct: 3   IAHISDLHIRPHGEKLYDFVDTNALISRHVATLNSIAKTTDSPDAVLITGDIVNCGQKQE 62

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV---------FIGEQWQI 124
           Y      +     P   +PGNHD    +  AL D    P + V         +  E++ +
Sbjct: 63  YAMARRILGQLTMPLYIIPGNHDNNANLLEALTDI-CPPLENVGKTGEHTIRYTIEEFPV 121

Query: 125 --LLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRN 182
             ++LDS + G  HGE+   Q+ WLE++L     R T + +HHHPLP+G + +D     +
Sbjct: 122 RFIMLDSSIGGELHGEIGREQMAWLEKELQKGTGRETAVCMHHHPLPSGNAHMDAIKCHD 181

Query: 183 AGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLAT 220
              L  +L+++P+V  L+CGH H+ +     GR L+ T
Sbjct: 182 GEALIEMLSRYPNVTRLICGHTHRSI-FQNVGRILICT 218


>UniRef50_Q4ZTD8 Metallophosphoesterase n=4 Tax=Pseudomonas syringae group
           RepID=Q4ZTD8_PSEU2
          Length = 265

 Score = 90.5 bits (223), Expect = 5e-17,   Method: Compositional matrix adjust.
 Identities = 56/212 (26%), Positives = 102/212 (48%), Gaps = 5/212 (2%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           I  I+DTH+  +       V++     A ++ I       DLI+ +GDL  +     Y  
Sbjct: 3   IAHISDTHVRPRGQLYQGVVDSNAMLAAAVDTINTLDPAPDLILFSGDLVDEGRPEEYAM 62

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSAL--QDAGISPAKRVFI---GEQWQILLLDSQV 131
             E +   R   + +PGNHD +  +  A    D  I+     F+       +I+ LD  V
Sbjct: 63  ARELLQPLRQKLLMIPGNHDHRQNLRDAFAEHDYFINDQDCSFVYSGSAPVRIIGLDISV 122

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
               HG++++  + WL+  LA  P++ TL+++H  P  +G  ++D +       L  V++
Sbjct: 123 PEQHHGDMTDTAIRWLDSTLALEPDKPTLIMMHQPPFSSGIPYIDAYRCERGERLAEVVS 182

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPST 223
           ++P ++ ++CGHIH+ + L + G  +   PST
Sbjct: 183 RYPAIERIVCGHIHRFMQLRFGGTLMCTAPST 214


>UniRef50_A4F6Q6 Cyclic nucleotide phosphodiesterase n=7 Tax=Actinomycetales
           RepID=A4F6Q6_SACEN
          Length = 255

 Score = 90.1 bits (222), Expect = 6e-17,   Method: Compositional matrix adjust.
 Identities = 57/197 (28%), Positives = 88/197 (44%), Gaps = 4/197 (2%)

Query: 35  GVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGN 94
           G  + E  +  L+ +R      D +V TGD+A       Y+     IA F  P     GN
Sbjct: 19  GDESVERLRRGLDCVRALDRLPDCVVITGDVADGGHRQEYEAVRAVIADFPVPVHLTTGN 78

Query: 95  HDFQPAMYSALQD----AGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERK 150
           HD    +           G   A+       + ++ LDS + G P G L   QL WL+  
Sbjct: 79  HDDPRGLAEVFGGTDVLGGAREARYAVDYPGFTLVALDSHMPGSPGGRLGADQLAWLDDV 138

Query: 151 LADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDL 210
           LA  P+   ++ +HH P+  G  +LD   + +A E   V+A+  +V  +L GH+H+ +  
Sbjct: 139 LARRPDVPAVVCVHHPPVAVGIPYLDGMGMEDAAEFAGVIARHRNVARVLAGHVHRAVVA 198

Query: 211 DWNGRRLLATPSTCVQF 227
           D+ G  L   PST +Q 
Sbjct: 199 DFAGATLTTAPSTHIQI 215


>UniRef50_Q2KTP2 Putative phosphohydrolase n=1 Tax=Bordetella avium 197N
           RepID=Q2KTP2_BORA1
          Length = 271

 Score = 89.7 bits (221), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 63/215 (29%), Positives = 110/215 (51%), Gaps = 14/215 (6%)

Query: 17  ILQITDTHLFAQKHEALLGVNT---WESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
           I QI+D H+   + +A   V T        A L A+ P     D+I+ +GDL      A 
Sbjct: 3   IAQISDLHIRLPRQKAYRVVETDRYLPPAVATLNALDPAP---DVIILSGDLTDFGRPAE 59

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV-FIGEQW--QILLLDSQ 130
           Y H  E +A  + P   +PGNHD + ++ +A  D      + + +  E +  ++++LD+ 
Sbjct: 60  YTHLRELLAPLQTPFYLMPGNHDARDSLRAAFPDHPYLQGEFIQYTVEHFPLRLIMLDTV 119

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHS-LRNAGELDTV 189
                HG L   +L WLE +LA+AP R TL+ +HH P   G + +D+   L+ A EL+ +
Sbjct: 120 EPMQSHGVLCARRLNWLEERLAEAPGRPTLIAMHHPPFQTGIAHMDKIGLLQGAKELEAL 179

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTC 224
           + ++ +++ ++ GH+H+ +   + G       STC
Sbjct: 180 VRRYDNIERIVSGHLHRTIFQRFGG----TIASTC 210


>UniRef50_A5GLK1 Predicted phosphohydrolase n=4 Tax=Synechococcus RepID=A5GLK1_SYNPW
          Length = 265

 Score = 89.7 bits (221), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 74/261 (28%), Positives = 117/261 (44%), Gaps = 23/261 (8%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           R++Q++D HL A+    + G +    +Q  L   +  Q + DL++ TGD   D++   Y 
Sbjct: 3   RLIQLSDPHLVARAEGRVRGRSALSLFQKALA--QALQEQPDLLLVTGDCCHDETWCGYV 60

Query: 76  HFAEGI------ASFRAPCV-WLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLD 128
              + +       + R  C+ +  GNHD  P    A+       A  V     W++L++ 
Sbjct: 61  RLRDAVDAAIQQQAARTVCLGFTAGNHD-HPQRLRAVLGRHWVVAPGVMDAGCWRLLVVS 119

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPE--RHTLLLLHHHPLPAGCSWLDQHSLRNAGEL 186
           S   G   G +   QL WL  +L +A    +  ++ LHH P+P G + +D   L +  +L
Sbjct: 120 SHRAGGCAGVIGGVQLSWLNTQLREAETLGKFVVVALHHPPVPIGDASMDTIGLSDGEQL 179

Query: 187 DTVLAKFPHVKYLLCGHIHQELDLDWNGR-------RLLATPSTCVQFKPHCSNFTLDTI 239
              L ++P V+ +L GHIHQ     W G         LL  PST V F P          
Sbjct: 180 MDSLKRWPAVRVVLFGHIHQH----WKGMAAPRSDLSLLGCPSTLVSFHPVQPCPLGRAW 235

Query: 240 APGWRTLELHADGTLTTEVHR 260
            PG R L+L  DG++   + R
Sbjct: 236 DPGGRLLDLMEDGSVQERLMR 256


>UniRef50_C1CX57 Putative Metallophosphoesterase; putative cAMP phosphodiesterase
           n=1 Tax=Deinococcus deserti VCD115 RepID=C1CX57_DEIDV
          Length = 267

 Score = 89.0 bits (219), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 62/215 (28%), Positives = 103/215 (47%), Gaps = 17/215 (7%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEF----DLIVATGDLAQDQSSA 72
           I Q++D H+ A+  +        ++  A+  A+  H  E     DL++ TGD  +    A
Sbjct: 3   IAQLSDPHVMAEPDD--------QAAHALRRAVS-HLLELPVLPDLVLITGDCTEHGEVA 53

Query: 73  AYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGI----SPAKRVFIGEQWQILLLD 128
            Y+ F   I     P   +PGNHD + AM SAL   G        + V      +++ LD
Sbjct: 54  EYETFRTLIQPLPMPVYVVPGNHDQRAAMLSALGRPGTLGLEGFMQYVVEAGPLRLIGLD 113

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           + + G   GEL   +L+WLE +L +AP R  ++ +HH P  +  + +D   LR+    + 
Sbjct: 114 THLPGQDAGELCAARLDWLEDRLTEAPGRPCVIFMHHPPARSSLNVMDGIGLRDPQAFEA 173

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPST 223
           +LA+  +V+ +L GH+H  +     G  L+  P T
Sbjct: 174 LLARHSNVERVLTGHLHMAMTRRCGGTLLMTAPGT 208


>UniRef50_C6DHP5 Metallophosphoesterase n=5 Tax=Proteobacteria RepID=C6DHP5_PECCP
          Length = 253

 Score = 88.2 bits (217), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 65/207 (31%), Positives = 102/207 (49%), Gaps = 11/207 (5%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++++Q++D HL AQ    L G +  +  +A +  I  H  + DL+V +GDL+ D S+A+Y
Sbjct: 1   MKLIQLSDLHLTAQGGN-LHGRDPEQQLKAAIADINAHHRDTDLVVISGDLSDDGSAASY 59

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQP---AMYSALQDAGISPAKRVFIGEQWQILLLDSQV 131
              A  +A  + P     GNHD +    A +  L D          +G+   ++LLDS  
Sbjct: 60  TFLASVLAELQVPWRVTMGNHDDREMFLAQFPTLVDENGFVQSVTTVGDDC-VILLDSLH 118

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGE----LD 187
            G   G L   +L W  R+L  A  ++  L LHH P+  G   LD  S+R A E    L 
Sbjct: 119 AGEVAGTLCSERLTWFARQLQAAEGKNVFLFLHHPPMSIGLPALD--SVRLAPEAAEALY 176

Query: 188 TVLAKFPHVKYLLCGHIHQELDLDWNG 214
            V  +F +V+++  GH+H+     W G
Sbjct: 177 QVCHRFGNVRHISAGHVHRPASGGWRG 203


>UniRef50_Q1GM28 Metallophosphoesterase n=3 Tax=Rhodobacteraceae RepID=Q1GM28_SILST
          Length = 270

 Score = 88.2 bits (217), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 59/217 (27%), Positives = 103/217 (47%), Gaps = 13/217 (5%)

Query: 18  LQITDTHLFAQKHEALLGVNTWESYQAVLEAIR---PHQHEFDLIVATGDLAQDQSSAAY 74
           +Q+TDTH+ ++   A    +T  +    ++ I    P     D +V TGDL    S+  Y
Sbjct: 5   IQLTDTHIVSEGSLAYGRSDTATALARAVDTINSRLPVLDPVDCVVVTGDLTDHGSAEEY 64

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQ-------ILLL 127
            H  + +A    P   +PGNHD + AM +A       PA       QW        ++ L
Sbjct: 65  AHLRQLLAPLNVPVRAIPGNHDTREAMRAAFATEDWMPASGPI---QWHHDFGPFAMVGL 121

Query: 128 DSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELD 187
           D+ V G P+G + E  L +L R L   P++  ++  HH  +P+G + +D+++LRN   + 
Sbjct: 122 DTLVEGAPYGMVCEAGLGFLARSLKTTPDKPLVVATHHPWIPSGMADMDRNNLRNGPAML 181

Query: 188 TVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTC 224
            +L +     +++ GH+H+ +    +G      P+ C
Sbjct: 182 DLLREHDAPVHVISGHLHRAMSALVDGVLHQVAPAPC 218


>UniRef50_B1A0M0 Ser/Thr protein phosphatase family protein n=3 Tax=Bacteria
           RepID=B1A0M0_9BACT
          Length = 263

 Score = 87.0 bits (214), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 64/214 (29%), Positives = 98/214 (45%), Gaps = 6/214 (2%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
           + + + ITD HL  +      GV T     A L+ I     +    V +GDLA+     A
Sbjct: 2   KTKFIHITDIHLVDEGLLLNGGVPT-ARLDACLDDISRWHPDAAFCVISGDLAEFAEVEA 60

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV---FIGEQWQILLLDSQ 130
           YQ     +A +  PC  L GNHD +    S   D      + V   F  EQ   L LD+ 
Sbjct: 61  YQALKARLAVYPLPCFLLIGNHDDRAVFQSVFPDHPKDMNEFVQHRFEIEQGVFLFLDTT 120

Query: 131 VFG--VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
             G  V  G+L  ++L+WL+++LA+A ++ T L LHH P   G  ++D   L  A     
Sbjct: 121 KEGRDVHEGQLCSYRLDWLKQQLAEAGDKPTYLFLHHPPFEIGIPYVDNIRLIEAEAFAK 180

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPS 222
            L     ++++  GH+H+   ++W G    + PS
Sbjct: 181 ALRHGRDIRHVFYGHVHRMTYVNWRGISFTSLPS 214


>UniRef50_Q5Z214 Putative phosphodiesterase n=1 Tax=Nocardia farcinica
           RepID=Q5Z214_NOCFA
          Length = 495

 Score = 86.3 bits (212), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 65/214 (30%), Positives = 97/214 (45%), Gaps = 17/214 (7%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           + Q++DTH         LG    E  + V+  +    H  D I+ TGD+ +   S   + 
Sbjct: 4   VAQVSDTHFD-------LGARNNERVERVMAFLADLAHRPDAILVTGDVTE---SGKPEQ 53

Query: 77  FAEGIASFRA--PCVWLPGNHDFQPAMYSAL--QDAGISPAKRVFIGEQWQILLLDSQVF 132
           +AE   + +A  P   +PGNHD + A  + L  +    SP   V       +++LD+ + 
Sbjct: 54  YAEARVALQADIPVWAIPGNHDERAAFRTELLGEQPSDSPINHVHRVGALTVIMLDTTIP 113

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAG--CSWLDQHSLRNAGELDTVL 190
           G P G + E    WL   LADAP    ++L  HHP PA      +D  +L     L  V+
Sbjct: 114 GEPGGRIEEDTYRWLREVLADAPATGPIVLAMHHP-PARLHSPIVDDIALAEPDRLADVV 172

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTC 224
           A  P ++ +L GH H      + GR LL  PST 
Sbjct: 173 AADPRIRAVLTGHAHSAAATTFAGRPLLIAPSTA 206


>UniRef50_A0NY27 Metallophosphoesterase n=2 Tax=Rhodobacteraceae RepID=A0NY27_9RHOB
          Length = 270

 Score = 86.3 bits (212), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 61/219 (27%), Positives = 93/219 (42%), Gaps = 13/219 (5%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQ---AVLEAIRPHQHEFDLIVATGDLAQDQSS 71
            +I+QI+DTH+  +   A   V+T  +     A +  + P     DL++ TGDL +  + 
Sbjct: 2   TKIIQISDTHIVPEGTLAYDQVDTAAALAETVATINRLLPRIGPVDLVIVTGDLTEHGTP 61

Query: 72  AAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQV 131
             Y  F   +A    P   LPGNHD +  M  +       P         WQI L D  V
Sbjct: 62  EEYDRFKNLMADLELPYRVLPGNHDRREPMRESFSGENWMPRTGPV---NWQIDLEDFAV 118

Query: 132 FGV-------PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAG 184
            G+        HG L    L +L   L D  ++  L+  HH P   G   +D  +L +A 
Sbjct: 119 VGLDSLTENAAHGTLEAATLSFLTDALTDIGDKPALVGFHHPPFAVGIEAMDAQNLHDAN 178

Query: 185 ELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPST 223
            L + L+       L+CGH+H+ +   ++G      P T
Sbjct: 179 SLGSALSLHSGQVRLVCGHLHRSIAGLFSGSLCQVCPGT 217


>UniRef50_A6W423 Metallophosphoesterase n=1 Tax=Kineococcus radiotolerans SRS30216
           RepID=A6W423_KINRD
          Length = 274

 Score = 85.9 bits (211), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 76/250 (30%), Positives = 111/250 (44%), Gaps = 25/250 (10%)

Query: 16  RILQITDTHLFAQK--HEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
           R+LQ++DTHL A    H  L  V+T  +    LEA+R      D +V +GD++ D + A+
Sbjct: 3   RVLQLSDTHLMAAGALHNGL--VDTTAALVHALEALR-DVGPLDAVVVSGDVSDDGTVAS 59

Query: 74  YQHFAEGIASFRAP----CVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDS 129
           Y+   + +  F A      V+  GNHD        L      P + V      +I++LDS
Sbjct: 60  YEAARDLVGGFAAERGAVAVFAMGNHDVAGPFEQVL-----GPTRSVHDVAGVRIVVLDS 114

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
            V G  +GEL   QL W    LAD   R +++++HH PLPA     +   L+   EL   
Sbjct: 115 SVPGRGYGELPAEQLSWAREVLADPAPRGSVVVVHHSPLPAPTVLHEGLRLQRPAELLDA 174

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQF-KPHCSNFTLDTIAPGWRTLEL 248
           LA    V+ +L GH H               PS    F  P  +N     +APG   + L
Sbjct: 175 LAGT-DVRAVLSGHYHHPFAATL--------PSGLAAFVAPAVANRCDVLVAPGRERI-L 224

Query: 249 HADGTLTTEV 258
              G L  ++
Sbjct: 225 RGSGALLVDL 234


>UniRef50_Q89MQ1 Bll4141 protein n=1 Tax=Bradyrhizobium japonicum RepID=Q89MQ1_BRAJA
          Length = 283

 Score = 85.5 bits (210), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 60/200 (30%), Positives = 96/200 (48%), Gaps = 10/200 (5%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           + + ITDTHL A     L G++      A +  I  HQ +    V TGDL       +Y 
Sbjct: 4   KFIHITDTHL-ANPGLKLYGLDPRARLDAAIADINKHQSDAAFAVVTGDLTHWGEPESYA 62

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDA-----GISPAKRVFIGEQWQILLLDSQ 130
           +FA+ +A+ + P + + GNHD + A    L+ A     G     R  I E    + LD+ 
Sbjct: 63  NFADAMAALKIPYIAMVGNHDKRVACLDGLKAAPRDSNGFVQGTR--ITEHGLFVFLDTL 120

Query: 131 VFGVPHGELSEFQLEWLERKLADAP-ERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
                 GE+   +L WL   LA AP +   ++ +HH P P G   +D+ SL+ + E   V
Sbjct: 121 DETSHAGEMCAKRLGWLASTLAAAPADMPFVVFMHHPPFPVGVHAMDEISLKQSPEFAEV 180

Query: 190 LAKF-PHVKYLLCGHIHQEL 208
           +A +   +++L  GH+H+ +
Sbjct: 181 IAPYRSRIRHLFFGHVHRPI 200


>UniRef50_Q0FF25 Putative uncharacterized protein n=1 Tax=Rhodobacterales bacterium
           HTCC2255 RepID=Q0FF25_9RHOB
          Length = 275

 Score = 85.1 bits (209), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 53/221 (23%), Positives = 108/221 (48%), Gaps = 11/221 (4%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESY-QAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++L I+D HL ++K   ++G++    + +A+  A++ H  + + ++  GD+      + Y
Sbjct: 3   KVLVISDIHLRSKKRN-IIGLDPLRQFTEALSHALKKHP-DAEHMILIGDMTHSGHVSEY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPA----KRVFIGEQWQI---LLL 127
           +       +++ P  ++ GNHD +        +  +       K++ +G+   I    L 
Sbjct: 61  EMLKRATNTYKIPITFMLGNHDNRSNFKKVFPEIPLDNEGYLQKKISLGDDVLICLDTLN 120

Query: 128 DSQVFGVPH-GELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGEL 186
            S    + H G+L E +LEWLE++L+ A  +   +  HH P   G   +D+  L N+ +L
Sbjct: 121 SSPQLEIEHEGKLCEKRLEWLEQELSQAKNKRISIFTHHPPHNIGFPGMDKIKLSNSADL 180

Query: 187 DTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQF 227
             ++ K+ + K++  GH+H+ +  + NG       STC Q 
Sbjct: 181 FNIIKKYKNTKHIFSGHVHRSISGNTNGIGFTIFKSTCHQM 221


>UniRef50_D2PQZ3 Metallophosphoesterase n=1 Tax=Kribbella flavida DSM 17836
           RepID=D2PQZ3_9ACTO
          Length = 293

 Score = 84.7 bits (208), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 71/234 (30%), Positives = 109/234 (46%), Gaps = 23/234 (9%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
           R RIL ++DT +     +   GV+   + + +L   R H  + DL+V +GD+A D S   
Sbjct: 4   RHRILHLSDTQVGRDGRDED-GVDAVAALERMLHDAR-HLPDLDLVVVSGDIADDGSVEG 61

Query: 74  YQHFAEGIASFRA----PCVWLPGNHDFQPAMYSALQDAGISP-------------AKRV 116
                + +A+F A    P V+  GNHD +    +AL    + P              +RV
Sbjct: 62  CVAVRDRVAAFAAARGIPHVYCTGNHDDRSTFATALGSGHLGPDGTDLGRLMESGGPERV 121

Query: 117 FIGE--QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSW 174
            + E    +I+ LDS V G  HG LS+ QL+WL   L       T++++HH P+    S 
Sbjct: 122 AVSEVNGVRIVTLDSLVPGAAHGALSDRQLQWLANLLETPASSGTVIVVHHPPVYLESSV 181

Query: 175 L-DQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQF 227
           L     LR++  L +VLA    V+ +LCGH H +L     G  +  TP    + 
Sbjct: 182 LMGTVGLRDSDRLASVLAGR-DVRAVLCGHFHLQLAATLAGVPVWVTPGVVTRI 234


>UniRef50_C8SU16 Metallophosphoesterase n=1 Tax=Mesorhizobium opportunistum WSM2075
           RepID=C8SU16_9RHIZ
          Length = 276

 Score = 84.7 bits (208), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 54/197 (27%), Positives = 94/197 (47%), Gaps = 4/197 (2%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++I+Q+TD HL  ++ E   G +  +   + +  I  H  +  L V TGDL +  +  +Y
Sbjct: 1   MKIIQVTDVHL-GRQGERRFGADLHQRLASCIAHINAHHADAALCVFTGDLTETGAPESY 59

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISP---AKRVFIGEQWQILLLDSQV 131
                 +++   P   LPGNHD +  + +A  +  +      + V    +  +L LD   
Sbjct: 60  ADLRTALSTLSVPWRLLPGNHDRRVNLVAAFPEIPVDENGFVQSVHDSGEEVLLFLDCLA 119

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
            G   GEL   +L WLE +L  +  R   + LHH P+  G   LD  +L   G L  +L 
Sbjct: 120 EGRVEGELCGTRLAWLEARLEQSAGRPAYIFLHHPPVALGLPQLDPLALEQPGRLLGLLR 179

Query: 192 KFPHVKYLLCGHIHQEL 208
              +V+++  GH+H+++
Sbjct: 180 DHGNVRHIFFGHVHRDI 196


>UniRef50_Q1GWA3 Metallophosphoesterase n=1 Tax=Sphingopyxis alaskensis
           RepID=Q1GWA3_SPHAL
          Length = 282

 Score = 84.7 bits (208), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 57/214 (26%), Positives = 99/214 (46%), Gaps = 7/214 (3%)

Query: 17  ILQITDTHL-FAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           I QITD H+ F   + A       +    VL+ +    +  DL++ATGD+     + +Y+
Sbjct: 3   IAQITDIHIGFDPDNPAEYNRKRLDE---VLDVLIEGPNRPDLLLATGDITDRGDADSYR 59

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQ--DAGISPAKRVFIGEQWQILLLDSQVFG 133
             A   +    P     GNHD +   ++     D G    +      + +++ +D+   G
Sbjct: 60  RLATAFSRCPFPVWPSVGNHDLRDNFHARFPGFDDGNGFVQYTVELPELRLVTIDTLEEG 119

Query: 134 VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRN-AGELDTVLAK 192
              G   E +  WL+ +LA AP R T +++HH P+ +G  W++ H           V+ +
Sbjct: 120 RHGGAFCERRAAWLDAELAKAPARPTYIVMHHPPVESGIEWMNTHPDEPWVATFTDVVRR 179

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQ 226
            P V+ L+CGH+H+ + + W GR +    ST  Q
Sbjct: 180 HPQVRGLICGHLHRSVTVAWEGRTIAICSSTAPQ 213


>UniRef50_Q1MS94 Phosphodiesterase n=1 Tax=Lawsonia intracellularis PHE/MN1-00
           RepID=Q1MS94_LAWIP
          Length = 267

 Score = 84.3 bits (207), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 61/239 (25%), Positives = 108/239 (45%), Gaps = 11/239 (4%)

Query: 12  EARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
           ++ ++ + I+DTH+ AQ    +   N     Q  ++ I+    +   ++ TGD+  D S 
Sbjct: 2   QSIIKFIHISDTHISAQGC-LVYDNNPRVKLQTCIDEIKRDHLDAAFLILTGDVTNDGSM 60

Query: 72  AAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQI---LLLD 128
             +    E ++    P   + GNHD + ++++A+ +    P   V       +   ++LD
Sbjct: 61  ECFSFLQEVLSELPMPWYLVMGNHDLKQSLFTAIPEYPRDPNGFVQFTVDTPVGLCIILD 120

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQ--HSLRNAGEL 186
           + +     G L   +L+WL  +L  A  +  LL  HH P   G   +D   HSL+N+ E 
Sbjct: 121 TTIANQSSGILCAARLDWLANELKQA-TKPVLLFFHHPPFSLGIPSMDAIVHSLKNSEEF 179

Query: 187 DTVLAKFP-HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWR 244
             VL  +   ++++  GHIH+ +   WNG      PST  Q      NF  D    G++
Sbjct: 180 FAVLKPYKDKIRHMFVGHIHRPICGSWNGIPFSCAPSTAHQIA---LNFQSDKSVLGFK 235


>UniRef50_B0UF90 Metallophosphoesterase n=2 Tax=Methylobacterium RepID=B0UF90_METS4
          Length = 275

 Score = 84.0 bits (206), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 67/232 (28%), Positives = 104/232 (44%), Gaps = 14/232 (6%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           I QITD HL  +   A     T    +  ++A+   Q   D+++ TGDL        Y  
Sbjct: 3   IAQITDLHLRPRGRPAYRVAETNMLVERAVDALASLQPRPDVVLVTGDLTDCGLPEEYAL 62

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIG---EQWQILL--LDSQV 131
               +     P   +PGNHD + A+ +AL  A +  A   F+    + W + L  LD+ V
Sbjct: 63  LRGLLGRLPLPVFVVPGNHDRREALRAALPAAWLPGAMEEFVQYVVDDWPVRLIGLDTLV 122

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNA-GELDTVL 190
            G  HG L   +L +LE  LA   +R TL+ LHH P   G   +D+  L +    L  ++
Sbjct: 123 AGASHGALCARRLAFLEEALAAGGDRPTLVFLHHPPFACGMEGMDRIRLLDGEPRLRALI 182

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPG 242
              P+V+ +LCGH H+ + + + G        T  Q  P  ++     + PG
Sbjct: 183 EAHPNVERILCGHHHRPIQVRYAG--------TIAQVAPGVAHQVALDLNPG 226


>UniRef50_D2PMS5 Metallophosphoesterase n=1 Tax=Kribbella flavida DSM 17836
           RepID=D2PMS5_9ACTO
          Length = 249

 Score = 83.6 bits (205), Expect = 6e-15,   Method: Compositional matrix adjust.
 Identities = 65/219 (29%), Positives = 100/219 (45%), Gaps = 13/219 (5%)

Query: 49  IRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHD----FQPAMYSA 104
           +R      D+++ TGDLA   +   Y   A  +A+F  P + LPGNHD    F+  + + 
Sbjct: 29  VRSFTRPVDVVLVTGDLADHGTE--YAEVAAELAAFDVPVLVLPGNHDLSEPFRAGLTAY 86

Query: 105 LQDAGIS-PAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLL 163
           +   G   P  +V      + +LLD+ V G  HGEL+   L WL+  L++  +    +  
Sbjct: 87  VDSPGAGHPVHQVRDVGGARFVLLDTTVPGEDHGELAAESLGWLDGVLSEPTDGPVFVAF 146

Query: 164 HHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATP-- 221
           HH P+      +DQ  LR+A     VL + P V  L  GH+H  +   +    LL  P  
Sbjct: 147 HHPPVGLHAPAIDQWLLRDAAPFAAVLRRHP-VTALFAGHLHNGVATTFADLPLLLAPGI 205

Query: 222 --STCVQFKPHCSNFTLDTIAPGWRTLELHA-DGTLTTE 257
             +  + F+P  +   LD  AP    L LH  D  + T+
Sbjct: 206 RSAVPLPFEPAAAQGLLDPTAPPGLALHLHTPDAAVVTK 244


>UniRef50_A1AWV4 Metallophosphoesterase n=5 Tax=Bacteria RepID=A1AWV4_RUTMC
          Length = 234

 Score = 83.6 bits (205), Expect = 6e-15,   Method: Compositional matrix adjust.
 Identities = 59/240 (24%), Positives = 109/240 (45%), Gaps = 16/240 (6%)

Query: 18  LQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHF 77
           +QI+D H+     E  +GVNT           +    + D ++ +GDL  + +  +Y+  
Sbjct: 7   VQISDCHI--DNVEYAMGVNT--HVNLKKIINKIINIDTDALLISGDLTHNGTITSYKTL 62

Query: 78  AEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHG 137
            + +   +   + + GNHD    + +       S     F   +W+I+  +S       G
Sbjct: 63  QQILFPVQIKLLVISGNHDIDNNLNTIFSKNLFSQ----FTLRKWEIISTNSVQTSKTSG 118

Query: 138 ELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVK 197
            L++ +L+ L   L  +  ++ L++LHH  +P   +W D  SL N   L  VL K+P ++
Sbjct: 119 FLTKNELKKLNFNLTQSIAKYILIVLHHPIVPMNSTWDDSLSLENPKALFNVLDKYPKIQ 178

Query: 198 YLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTE 257
            +L GH HQ  +    G ++++ PST +QF         +    G+    L+ +G LT +
Sbjct: 179 AILFGHAHQAAEFSRLGVKIISCPSTALQFN--------NETRIGFNHYTLYDNGQLTID 230


>UniRef50_C5T0E1 Metallophosphoesterase n=1 Tax=Acidovorax delafieldii 2AN
           RepID=C5T0E1_ACIDE
          Length = 267

 Score = 83.2 bits (204), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 59/197 (29%), Positives = 93/197 (47%), Gaps = 6/197 (3%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           + + +TDTHL  ++  AL G++     Q  +E I  H  +   +V TGDL       AY+
Sbjct: 6   KYIHLTDTHL-VKEAGALYGLDPKLRLQQAVEHINCHHADARAVVITGDLTHYGHDNAYE 64

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAM---YSALQDAGISPAKRVFIGEQWQILLLDSQVF 132
           H  E +A+   P   + GNHD +      +  +        + V   E++  + LD+   
Sbjct: 65  HLRECLAALSMPVYPILGNHDSRVNFVRHFPHIPCDANGFVQYVVQLERYTAIFLDTNEP 124

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
           GV  G   E + +WL R    A E+  LL +HH   P G + +D  SLRN G  +  +A 
Sbjct: 125 GVHWGVFCEQRAQWL-RAALQAAEKPVLLFMHHPFFPIGITSMDDISLRNTGPFEAAIAS 183

Query: 193 F-PHVKYLLCGHIHQEL 208
           F P + +   GHIH+ +
Sbjct: 184 FEPRIAHCFFGHIHRPI 200


>UniRef50_C6WAT1 Metallophosphoesterase n=1 Tax=Actinosynnema mirum DSM 43827
           RepID=C6WAT1_ACTMD
          Length = 245

 Score = 81.6 bits (200), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 70/239 (29%), Positives = 95/239 (39%), Gaps = 10/239 (4%)

Query: 21  TDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEG 80
           +DTH     H A          + V+  +R      D  V TGD+  +     Y+  A  
Sbjct: 8   SDTHFDGGDHAA-------PRAERVVGYLRGLARPVDAAVLTGDVVDNGLRVEYEEAARV 60

Query: 81  IASFRAPCVWLPGNHDFQPAMYSAL--QDAGISPAKRVFIGEQWQILLLDSQVFGVPHGE 138
           +     P + LPGNHD +      L  +  G  P  RV    +  + L DS V G   G 
Sbjct: 61  LGGLGRPLLALPGNHDSRSPFREVLLGEGPGDGPVNRVARVGEVVLALCDSTVPGQDGGA 120

Query: 139 LSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKY 198
           L++  LEWL+  LA+A    TL+ LHH P+P     LD   L     L  V+     +  
Sbjct: 121 LADETLEWLDAVLAEAAGAPTLVCLHHPPVPVRHPVLDPIGLDAPERLARVVRGRKGLLA 180

Query: 199 LLCGHIHQELDLDWNGRRLLATPSTCVQFKPH-CSNFTLDTIAPGWRTLELHADGTLTT 256
           LLCGH H  +     G  +L+ P       P        D  AP      +  DG LTT
Sbjct: 181 LLCGHSHSPMVGSLAGVPVLSAPGVVSTLAPPWEGEKPNDRGAPPALAFHVVEDGQLTT 239


>UniRef50_D2AYX4 Metallophosphoesterase n=10 Tax=Actinomycetales RepID=D2AYX4_STRRD
          Length = 247

 Score = 81.3 bits (199), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 66/215 (30%), Positives = 93/215 (43%), Gaps = 23/215 (10%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           + QI+D HL   +               V++ +R   H  D ++ TGD+A   + A Y+ 
Sbjct: 5   LAQISDLHLDGSE-------RATRRATRVMDYLRALPHAVDALLVTGDIADHGTEAEYEE 57

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSAL--QDAGISPAKRVFIGEQWQILLLDSQVFGV 134
            A  I S   P +  PGNHD +PA   AL  + A   P  RV       IL+ DS + G 
Sbjct: 58  AAR-ILSAPFPVLTCPGNHDARPAYRKALLGEPAADGPINRVHHVTGTAILMCDSTIPGR 116

Query: 135 PHGELSEFQLEWLERKLADAPE-RHTLLLLH------HHPLPAGCSWLDQHSLRNAGELD 187
             G L    L+W++  LA  PE    L+  H      HHPLP      D   LR   +L 
Sbjct: 117 DEGRLDAETLDWIDTTLAGLPEGTPALIAFHQPPVELHHPLP------DSGMLRRPEDLA 170

Query: 188 TVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPS 222
            +L   P V  ++ GH H      + GR L+  P+
Sbjct: 171 ALLDAHPRVAAVVTGHAHTAAASTFAGRPLIVGPA 205


>UniRef50_D1XS68 Metallophosphoesterase n=1 Tax=Streptomyces sp. ACTE
           RepID=D1XS68_9ACTO
          Length = 262

 Score = 80.9 bits (198), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 56/185 (30%), Positives = 78/185 (42%), Gaps = 17/185 (9%)

Query: 55  EFDLIVATGDLAQDQSSAAYQHFAEGIASF--RAPCVWLPGNHDFQPAMYSAL------- 105
             D ++ TGD+    ++  Y    E +A    R   +  PGNHD +      L       
Sbjct: 35  RVDAVLITGDIVDRGTAEEYHQAREVLAPLYERHEVLLCPGNHDSRAPYREVLLGGGGGG 94

Query: 106 --------QDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPER 157
                      G +P   V      ++L+ DS V G P G L    L WL+  LA AP+R
Sbjct: 95  SGSGGGDDGGGGTAPVNEVRDVGGVRVLMCDSSVPGRPEGLLEAATLSWLDDALAAAPDR 154

Query: 158 HTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRL 217
              + LHH P+P G  ++D+  LR    L  VLA+   V  +LCGH H      + G  L
Sbjct: 155 PAFVALHHPPVPLGLPYIDRIGLREPDALAKVLARHAQVVAVLCGHAHTAAATSFAGLPL 214

Query: 218 LATPS 222
           L  P 
Sbjct: 215 LCAPG 219


>UniRef50_B6WYD4 Putative uncharacterized protein n=1 Tax=Desulfovibrio piger ATCC
           29098 RepID=B6WYD4_9DELT
          Length = 274

 Score = 80.1 bits (196), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 63/220 (28%), Positives = 95/220 (43%), Gaps = 10/220 (4%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + ILQI+D HL      +   V+T    +     +       D IV TGDLA      AY
Sbjct: 1   MEILQISDLHLRGDGKLSFRKVDTPACLRTAAAYLHALNRMPDAIVITGDLADSGDEHAY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSAL-----QDAGISP--AKRVFIGEQWQILLL 127
               E +     P   +PGNHD +  M + L     +++ + P     V +GE  ++++L
Sbjct: 61  HMLYEALGDLPVPIYAVPGNHDRRDRMRAILKGWVPEESPVPPRVCHCVDMGE-LRLVML 119

Query: 128 DSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELD 187
           DS   G   G   E    WL+  L +   R  L+ +HH P   G   +D+     A  L 
Sbjct: 120 DSMEPGSHSGHCPEAMARWLDACLQEDSSRPALVFMHHPPFITGMGAMDE-PFEGADLLR 178

Query: 188 TVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQF 227
            VL++ P  + L CGH+H+ +   W     L  PS  +Q 
Sbjct: 179 DVLSRAPWAR-LCCGHMHRPIFTAWAQGLALTVPSISMQI 217


>UniRef50_Q2J3S6 Metallophosphoesterase n=5 Tax=Rhodopseudomonas palustris
           RepID=Q2J3S6_RHOP2
          Length = 274

 Score = 80.1 bits (196), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 63/208 (30%), Positives = 95/208 (45%), Gaps = 11/208 (5%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++ + +TDTH F  +   + G++  E  +A +  I     E   ++ TGDLA     AAY
Sbjct: 1   MKFVVLTDTH-FVARGRRIYGLDPAERLRAAIGCINRDHPEIAFVIVTGDLAHWGEDAAY 59

Query: 75  QHFAEGIASFRAPCVWLPGNHD----FQPAMYSALQDA-GISPAKRVFIGEQWQILLLDS 129
           +  AE +   RA  + L GNHD    F        +DA G     +VF  +   ++ LD+
Sbjct: 60  EALAEVLGELRALTILLMGNHDKRDGFARYFPGVPRDADGFVQTMQVF--DAATVVTLDT 117

Query: 130 QVFGVPH--GELSEFQLEWLERKLADAPERHTLLLLHHH-PLPAGCSWLDQHSLRNAGEL 186
                P+  G L + +L +LE  L  AP    LLL  HH P   G  ++D   L N    
Sbjct: 118 LNEAAPNHEGLLCDARLAFLEHALTSAPTDRPLLLFQHHPPFDTGLRYMDTIRLANPEAE 177

Query: 187 DTVLAKFPHVKYLLCGHIHQELDLDWNG 214
             V+A+     YL  GH+H+ +   W G
Sbjct: 178 WEVIARTRRPDYLFMGHLHRPIAGVWRG 205


>UniRef50_B5J8T8 Ser/Thr protein phosphatase family protein n=2 Tax=Rhodobacteraceae
           RepID=B5J8T8_9RHOB
          Length = 259

 Score = 79.7 bits (195), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 57/204 (27%), Positives = 97/204 (47%), Gaps = 6/204 (2%)

Query: 17  ILQITDTHLFAQKHE-ALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           I  I+D H+FA+  E +L+  +  ++ + V+  I     +   ++ TGDL    S+  Y 
Sbjct: 3   IAHISDFHIFAEAPETSLVRPDAADAARKVVADIAAFTPQIGAVMFTGDLTDGGSAEDYA 62

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQW----QILLLDSQV 131
              + ++    P   +PGNHD +P M ++        A      E W    +IL LD+  
Sbjct: 63  LLTDILSPLDVPVFVVPGNHDARPGMRASFAGKLPFEADPFLNYEAWFNDIRILALDTLW 122

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNA-GELDTVL 190
            G   G L + QL WL  +LA      TL+L+HH   P+  + LD  +L++   + + ++
Sbjct: 123 DGQIAGRLDQTQLVWLAERLAVPHHGLTLILMHHPAFPSQMAPLDAMTLQDGRADFERLI 182

Query: 191 AKFPHVKYLLCGHIHQELDLDWNG 214
           A +     +L GHIH+     W+G
Sbjct: 183 ANYNEPLRILSGHIHRPFQTLWHG 206


>UniRef50_B0P519 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=B0P519_9CLOT
          Length = 305

 Score = 79.7 bits (195), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 57/224 (25%), Positives = 100/224 (44%), Gaps = 10/224 (4%)

Query: 13  ARVRILQITDTHLFAQKHEALLGVNTWES-YQAVLEAIRPHQHEF-DLIVATGDLAQDQS 70
           A ++++QI+D HL      +    +T ++ +Q +        +E  +  V TGDL++  +
Sbjct: 13  AFMKVIQISDFHLRGDGKLSFQKADTMKALHQTIDYFCSMKDYELPEFFVVTGDLSEGGT 72

Query: 71  SAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDA-----GISPAKRVFIGEQ-WQI 124
              Y+   EG+     P   +PGNHD +        +       I P     I E   ++
Sbjct: 73  REGYEFMREGLRKLPRPVYIVPGNHDKRDFFLEMFTEETPVKEDIKPYICYTIDEYPVRV 132

Query: 125 LLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAG 184
           +++D+       G LS+   EWLE ++ + PE+ TL+  HH P   G   +D+     A 
Sbjct: 133 IVIDTSKPSCHSGGLSDRVAEWLEERITEYPEKPTLVFTHHPPFVTGLPAMDE-GFDQAD 191

Query: 185 ELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFK 228
            L  +L K  +V  L CGH+H  +   W+    +  P   +Q +
Sbjct: 192 RLAQILNKHENVT-LCCGHMHTAIFTSWHKIPCVTCPPIAMQME 234


>UniRef50_C7S9W5 Protein icc n=17 Tax=Bacteria RepID=C7S9W5_ECOLX
          Length = 274

 Score = 79.3 bits (194), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 56/219 (25%), Positives = 101/219 (46%), Gaps = 9/219 (4%)

Query: 20  ITDTHLFAQKHEALLG-VNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFA 78
           I+DTH F  + E L G ++   +   V+  +   +   D +V +GD+        YQ   
Sbjct: 6   ISDTH-FRSRGEKLYGFIDVNAANADVVSQLNALRERPDAVVVSGDIVNCGRPEEYQVAR 64

Query: 79  EGIASFRAPCVWLPGNHD----FQPAMYSALQDAGISPAKRVFIGEQW--QILLLDSQVF 132
           + + S   P   +PGNHD    F   ++      G  P    ++ + +  ++L +DS   
Sbjct: 65  QILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDPQNMRYVVDDFATRLLFIDSSHA 124

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
           G   G L++  + WLE +L +  ++   + +HH PLP G + +D  +  N   L  ++ +
Sbjct: 125 GTSKGWLTDETIGWLEAQLFEGGDKPATIFMHHPPLPLGNAQMDPIACENGHRLLELVER 184

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHC 231
           FP +  + CGH H  L +    + L++T    V   P+C
Sbjct: 185 FPSLTRIFCGHNH-SLTITQYLQALISTIPGTVHQVPYC 222


>UniRef50_C1AX97 3',5'-cyclic-nucleotide phosphodiesterase n=24 Tax=Actinomycetales
           RepID=C1AX97_RHOOB
          Length = 318

 Score = 79.3 bits (194), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 64/215 (29%), Positives = 100/215 (46%), Gaps = 10/215 (4%)

Query: 17  ILQITDTHLFAQKHEALLG-VNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           +L ++DTHL     + L G V++  + + ++  I       D +V TGDL       AY+
Sbjct: 21  VLHLSDTHLV--DDDLLYGAVDSEATLRQIVTEIEASHARPDALVFTGDLTDRGQPGAYE 78

Query: 76  HFAEGI----ASFRAPCVWLPGNHDFQPAMYSAL--QDAGISPAKRVFIGEQWQILLLDS 129
              E +    A+  A  +W  GNHD +    + L  Q+    P   V   +  +I+ LD+
Sbjct: 79  KLREIVEPVAATLGAQVIWAMGNHDDRGHFRAELLGQEPTYEPVDHVHDVDGLRIITLDT 138

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
            V G  HGE+SE QL WL ++LA      ++L LHH P+P          LR+   L  V
Sbjct: 139 TVPGHHHGEISESQLIWLAQQLAIPAPHGSILALHHPPVPCVLDLAVLVELRDQPRLADV 198

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTC 224
           L +   V+ +L GH+H      + G  +    +TC
Sbjct: 199 L-RGSDVRSILAGHLHYSTTATFAGIPVSVASATC 232


>UniRef50_A0NQD3 Ser/Thr protein phosphatase family protein n=1 Tax=Labrenzia
           aggregata IAM 12614 RepID=A0NQD3_9RHOB
          Length = 272

 Score = 79.0 bits (193), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 59/213 (27%), Positives = 96/213 (45%), Gaps = 7/213 (3%)

Query: 20  ITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAE 79
           +TD HL  +        +T    +  + +++    + D +V TGD+        Y     
Sbjct: 1   MTDLHLRPRGLACYRVSDTNMLAERAIRSLQSLTPKPDALVITGDITDGNDPREYALARS 60

Query: 80  GIASFRAPCVWLPGNHDFQPAMYSALQD----AGISPAKRVFIGEQWQILL--LDSQVFG 133
            ++    P   +PGNHD    M   L      AG    K  +  +   I L  LD+ + G
Sbjct: 61  ILSRVDMPVFLVPGNHDGTQVMRRELAGFPGLAGSLDDKICYTADIADIRLIALDTHIPG 120

Query: 134 VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKF 193
            P G L + QL+WL+ +L ++  + TL+ LHH P  +G   +D   L +A  L  V++  
Sbjct: 121 DPRGRLGQAQLDWLDGQLKES-SKTTLIALHHPPALSGIRHMDDIGLVDADALAEVVSPH 179

Query: 194 PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQ 226
            HV   LCGH+H+ +   + G+ +   PST  Q
Sbjct: 180 RHVARFLCGHLHRPIIASFAGKVMTLAPSTGHQ 212


>UniRef50_Q3JU10 Ser/Thr protein phosphatase family protein n=72 Tax=Burkholderiales
           RepID=Q3JU10_BURP1
          Length = 325

 Score = 78.6 bits (192), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 63/243 (25%), Positives = 102/243 (41%), Gaps = 23/243 (9%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           +  I+D H+      A   V+T       +  +   +   D ++ TGDL        Y H
Sbjct: 54  LAHISDLHIKRPGALAYRRVDTAAHLARCVARLNALEPRPDAVLVTGDLTDFGDDDEYAH 113

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQW----------QILL 126
               +A    P   L GNHD + AM  A       PA+      ++          +++ 
Sbjct: 114 LKALLAPLAMPYYLLVGNHDDRAAMRRAF------PARVELQSGEFVQYALDLGPLRVIA 167

Query: 127 LDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLR--NAG 184
           LDSQ+ G   G L + +L WL  +L  A +R  ++ LHH P   G   +D   L    + 
Sbjct: 168 LDSQIPGASGGTLCDARLAWLADQLDAARDRPVIVALHHPPFACGIGHMDAMRLAPDASS 227

Query: 185 ELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWR 244
            LD +L + P+V+ +LCGH+H+ +   + G     T ++ V    H   F L    P   
Sbjct: 228 RLDALLRRHPNVERVLCGHVHRTMFARFGG-----TIASAVPAPAHQVTFDLRDGGPSSF 282

Query: 245 TLE 247
           ++E
Sbjct: 283 SME 285


>UniRef50_UPI0001B53F99 metallophosphoesterase n=1 Tax=Streptomyces sp. AA4
           RepID=UPI0001B53F99
          Length = 253

 Score = 77.8 bits (190), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 74/234 (31%), Positives = 105/234 (44%), Gaps = 32/234 (13%)

Query: 44  AVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYS 103
           AV   +R  +   D + ATGDLA       Y+  AE +     P V  PGNHD +     
Sbjct: 24  AVTRYLRNLEKPVDAVFATGDLADHGLPGEYRRAAE-LLDLPVPVVVCPGNHDVRAPFRE 82

Query: 104 AL-----QDAGISPAKRVFIGEQWQILLL--DSQVFGVPHGELSEFQLEWLERKLA--DA 154
           AL      DA ++ A +V      ++LL+  DS + G   G L++  L WL+  LA  D 
Sbjct: 83  ALLGEPASDAPVNTATKV-----AEVLLVSCDSTIPGKGAGYLADETLAWLDETLAAHDG 137

Query: 155 PERHTLLLLHHHPLPAGCSWLDQHSLRNAGE--LDTVLAKFPHVKYLLCGHIHQELDLDW 212
           P   + +  HH PL  G   +D  ++R  GE  L  VL + P V  LLCGH+H     ++
Sbjct: 138 P---SFVAFHHPPLDVGVPLVD--AIRQTGEDRLAAVLKRHPGVAALLCGHVHTGAATEF 192

Query: 213 NGRRLLATP----STCVQFKPHCS-----NFTLDTIAPGWRTLE-LHADGTLTT 256
            G  +   P     + +  +P           LD ++P    L  LH DG LTT
Sbjct: 193 AGVPVRIAPGVVSGSLLPVEPGAGRGWDEGGPLDFVSPPSLLLHVLHDDGRLTT 246


>UniRef50_A8U260 Ser/Thr protein phosphatase family protein n=1 Tax=alpha
           proteobacterium BAL199 RepID=A8U260_9PROT
          Length = 268

 Score = 77.4 bits (189), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 56/217 (25%), Positives = 97/217 (44%), Gaps = 6/217 (2%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
            +QITD H+    +     V+T      ++  +         ++ TGDL  + S A Y+ 
Sbjct: 3   FVQITDLHVRESGNPLAGRVDTAGFLDRMVTRLNALNPRPGAVLITGDLIDNGSEAEYRL 62

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQD-----AGISPAKRVFIGEQWQILLLDSQV 131
             + +A+   P     GNHD + A  ++  D     AG +  +     +  ++L+LD+  
Sbjct: 63  LRQRLAALDMPVYLALGNHDGREAFRASFTDLDYWDAGTAFVQYAVDLDGVRLLVLDTHE 122

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGE-LDTVL 190
            G P G L   +L WL  +LA+     T++ +HH P+P G   +D   L    E    ++
Sbjct: 123 PGKPSGVLCLERLNWLSDRLAEDRSTPTVVAMHHPPVPVGMPNMDPSRLLAGAERFKELI 182

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQF 227
           A  P+V+ +L GH+H+ +   + G  L   P    Q 
Sbjct: 183 AGAPNVERILAGHLHRSVTARFAGTVLDVMPGVAHQI 219


>UniRef50_C6A0T0 Predicted phosphohydrolase n=6 Tax=Thermococcus RepID=C6A0T0_THESM
          Length = 504

 Score = 77.0 bits (188), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 57/256 (22%), Positives = 115/256 (44%), Gaps = 18/256 (7%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++I  I+DTH+ + +         ++ Y   L A   +  +++L++ TGD+  D     Y
Sbjct: 2   IKIAHISDTHITSGE--------AYKGYAYDLIANEINTLDYNLVIHTGDVTNDGLREEY 53

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
           +  +  +   + P + LPGNHD +   Y   Q   I P   ++  +   I+  DS +  +
Sbjct: 54  ERASYELKKIQKPLIVLPGNHDARNVGYELFQKY-IGPLNGIYEWKDLVIIWTDSTIPDL 112

Query: 135 PHGELSEFQLEWLERKLAD-APERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKF 193
             G +  ++  WL+ KL + + ++  ++  HHH +P   +  +++ L NAG++  +L K 
Sbjct: 113 NDGRIGGYKFRWLKEKLEEYSHKKFKIVASHHHLVPLPDTGRERNVLFNAGDVLELLLKH 172

Query: 194 PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGT 253
             V   LCGH H        G  L+   S C   +      T       +  +++  +G 
Sbjct: 173 -EVNLYLCGHKHVPNIYSVEG--LVVANSGCTSCRK-----TRKGDVNSYNMIKIKDNGK 224

Query: 254 LTTEVHRLADTRFQPD 269
           ++  + R+ +   + D
Sbjct: 225 ISVTIKRVTEDIHKRD 240


>UniRef50_C6CXY6 Metallophosphoesterase n=1 Tax=Paenibacillus sp. JDR-2
           RepID=C6CXY6_PAESJ
          Length = 276

 Score = 76.6 bits (187), Expect = 8e-13,   Method: Compositional matrix adjust.
 Identities = 59/194 (30%), Positives = 88/194 (45%), Gaps = 11/194 (5%)

Query: 20  ITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAE 79
           +TDTH+       L  ++     +AV   I     +   IV +GDL QD     Y+   +
Sbjct: 9   LTDTHVNVPGKTPLFSIDGGAKLRAVFAEIGRLSEKPAFIVISGDLTQDGDVEDYKFLRQ 68

Query: 80  GI----ASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV----FIGEQWQILLLDSQV 131
            I    A+   P     GNHD +P       +    P++      F+ E+ +I++L++QV
Sbjct: 69  LIDEEQAALGIPVYVALGNHDSRPFFREGYLNE--EPSEESYHYSFMHEELRIIMLNTQV 126

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
            G   G L E QL+WL  +LA      T+++LHH  +      +D H L N   L  V+A
Sbjct: 127 PGKHDGRLDEAQLDWLSNELASTAPAGTIVVLHHPVVATPSELMDSHLLENPEALADVIA 186

Query: 192 KFPHVKYLLCGHIH 205
               V  LL GHIH
Sbjct: 187 G-TDVIGLLSGHIH 199


>UniRef50_Q2RNL1 Metallophosphoesterase n=1 Tax=Rhodospirillum rubrum ATCC 11170
           RepID=Q2RNL1_RHORT
          Length = 283

 Score = 76.6 bits (187), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 66/226 (29%), Positives = 99/226 (43%), Gaps = 15/226 (6%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           I Q +D H+          V+T  + +A +  ++   H  DL++ TGDL Q      Y H
Sbjct: 3   IAQTSDLHIRPPGMLVGGVVDTAAALEACVAHLQALAHRPDLLLITGDLTQQGRPEEYAH 62

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQ---------DAGISPAKRV---FIGEQWQI 124
               +A    P +  PGNHD + A+ + L           AGI     +   F     ++
Sbjct: 63  LRRLLAPLDLPLLVCPGNHDDRAALRAGLDGLCPWPEPPGAGIPDGATLDLTFDLGPLRL 122

Query: 125 LLLDSQVFGVPHGELSEFQLEWLERKLADAP--ERHTLLLLHHHPLPAGCSWLDQHSLRN 182
           + LDS   G   G LS  Q  WL+  L++A   ++  +L LHH P P G   LD   L  
Sbjct: 123 IGLDSLRSGHSGGALSASQEAWLDSALSEAAFLDKPVVLFLHHPPFPMGIDHLDAARLDQ 182

Query: 183 AGELDTVLAKFP-HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQF 227
           +  L  +L + P  V  LLCGH H+ +   W+G  +   P+    F
Sbjct: 183 SETLGLLLDRHPGRVVRLLCGHAHRHVTTVWHGVAVTVCPAPAFAF 228


>UniRef50_D2QL03 Metallophosphoesterase n=1 Tax=Spirosoma linguale DSM 74
           RepID=D2QL03_9SPHI
          Length = 247

 Score = 75.9 bits (185), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 67/249 (26%), Positives = 107/249 (42%), Gaps = 23/249 (9%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQ---AVLEAIRPHQHEF--DLIVATGDLAQDQ 69
           +RI  +TD HL A+  E   GV+  +++    A L  ++P       D  ++ GD     
Sbjct: 1   MRIAFLTDMHLGAEG-ELPEGVDVRQNFLKALAFLTELKPSCLVLGGDFCISVGD----- 54

Query: 70  SSAAYQHFAEGIASFRAPCVWLPGNHDFQPAM----YSALQDAGISPAKRVFIGEQWQIL 125
            S+ YQ   + +     P   +PGNHD  P M    ++ + D            E    L
Sbjct: 55  -SSIYQWVKKQVDELPFPYYVIPGNHD-DPTMLAEVFNKMHDLHGGELYYALSLEGRPTL 112

Query: 126 LLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLD-QHSLRNAG 184
            LDS       G  S+ Q  W    L+   + + ++ +HH PLPA   ++D ++  R + 
Sbjct: 113 FLDSS-----KGAFSDQQWTWFRDYLSALRDNNIVVFMHHPPLPADVQFMDRKYPFRQSE 167

Query: 185 ELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWR 244
           E   ++   P    ++CGH H E  +      +L +PST  Q K     F +DT+  G R
Sbjct: 168 EFIELVRDLPCHVTVICGHYHVEKVVQRGNLLVLLSPSTFYQMKQDTVGFAVDTLRVGIR 227

Query: 245 TLELHADGT 253
            + L   GT
Sbjct: 228 EINLTTHGT 236


>UniRef50_Q0RKV8 Putative uncharacterized protein n=1 Tax=Frankia alni ACN14a
           RepID=Q0RKV8_FRAAA
          Length = 301

 Score = 75.9 bits (185), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 62/200 (31%), Positives = 92/200 (46%), Gaps = 19/200 (9%)

Query: 11  GEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQS 70
           G A + ++Q++DTHL          V+T+   + V   +         I+ TGDLA D S
Sbjct: 5   GPAELTLIQVSDTHLLPAGQLMHDRVDTFALLETVAATVASSTGPVAGILLTGDLADDGS 64

Query: 71  SAAYQHFAEGI----ASFRAPCVWLPGNHDFQPAMYSAL-QDAGIS-------------- 111
            A+Y+   + I    A+F AP V+  GNHD + A  + L   AG+               
Sbjct: 65  PASYRRLRQIIDPLAATFDAPVVYAMGNHDERLAFRAELLGGAGVPVGLDGQAGEWSTDH 124

Query: 112 PAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAG 171
           P   V + +  +++ LDS   G   G L++ QL WL   LA    R TLL++HH PLP+ 
Sbjct: 125 PCDSVHLVDGLRLVALDSTTPGRHDGWLTDAQLAWLADVLATPAPRGTLLIVHHPPLPSP 184

Query: 172 CSWLDQHSLRNAGELDTVLA 191
              +    L  A  L  V+A
Sbjct: 185 VPTVHLLRLAAAERLADVVA 204


>UniRef50_Q6ACA7 Putative uncharacterized protein n=1 Tax=Leifsonia xyli subsp. xyli
           RepID=Q6ACA7_LEIXX
          Length = 280

 Score = 75.5 bits (184), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 62/200 (31%), Positives = 90/200 (45%), Gaps = 11/200 (5%)

Query: 13  ARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA 72
           AR+RIL ++DTHL          V+T  +   VL A        D++ A+GDL+ D S A
Sbjct: 3   ARLRILHLSDTHLCGDGRLHYGMVDTLAALDRVL-AHASSLDAVDMVAASGDLSDDGSPA 61

Query: 73  AYQHFAEGI----ASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLD 128
           +Y+   E +    A   A   +  GNHD   A  S L      P +R      ++IL +D
Sbjct: 62  SYRLLQERLEPWAAERGAVVAYAMGNHDLPDAFESVL-----GPRERALDANGFRILTVD 116

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           + V    +G +   QL+ L   LA+  E  T ++LHH P P      D   L +   L  
Sbjct: 117 TTVPCAGYGRVDTAQLDRLSEALAEPSEHGTAIVLHHPPAPPTTRLFDTLRLVDPEPLLE 176

Query: 189 VLAKFPHVKYLLCGHIHQEL 208
           V +    V+ +L GH H  L
Sbjct: 177 VCSAG-DVRLILAGHYHHAL 195


>UniRef50_A5V3T9 Metallophosphoesterase n=2 Tax=Sphingomonadaceae RepID=A5V3T9_SPHWW
          Length = 289

 Score = 75.5 bits (184), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 51/174 (29%), Positives = 76/174 (43%), Gaps = 4/174 (2%)

Query: 57  DLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPA--K 114
           D +  TGDL      A+Y+     I     P     GNHD + AM     D  +     +
Sbjct: 41  DRLFLTGDLTDHGDVASYERLKGLIDGCGFPVHLCVGNHDDRAAMKQVFPDLPVEDGFVQ 100

Query: 115 RVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSW 174
            V    + +I++LD+   G   G     +  WL+ +LA+ P +  L++LHH P+  G  W
Sbjct: 101 YVIDEPEVRIIVLDTLDPGHHGGAFGHRRAGWLKARLAEVPGKPVLIVLHHPPIETGIPW 160

Query: 175 LDQHSLRN-AGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQF 227
           +  H        LD  +   P V  ++ GHIH+ +   W GR L   PST  Q 
Sbjct: 161 MTAHQTEPWVVMLDKAIGDRPGVT-MISGHIHRSITTSWRGRMLAVAPSTAPQV 213


>UniRef50_A4AIJ2 Putative uncharacterized protein n=1 Tax=marine actinobacterium
           PHSC20C1 RepID=A4AIJ2_9ACTN
          Length = 305

 Score = 75.5 bits (184), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 60/214 (28%), Positives = 96/214 (44%), Gaps = 7/214 (3%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           +L ++DTH  A        +++    + +   +       + IV TGDLA      AY+ 
Sbjct: 15  VLHLSDTHFLAGSGRLYDTLDSEAKLRQLFAELEASGSRPEAIVFTGDLADKGDEVAYRE 74

Query: 77  FAEGI--ASFR--APCVWLPGNHDFQPAMYSALQD--AGISPAKRVFIGEQWQILLLDSQ 130
               +  A+ R  A  VW+ GNHD +    + L D  A   P  RV      +I+ LDS 
Sbjct: 75  IRAIVEPAAERLGAHIVWVMGNHDDRRNFATTLLDEPASEQPIDRVTDINGLRIISLDST 134

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
           V G  HG +++ QL WL   LA      T+L +HH P+P+         LR+  EL  V+
Sbjct: 135 VPGQHHGHVTDAQLLWLHNVLATPAPHGTILAMHHPPVPSVLDLAVTVELRSQKELAAVI 194

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTC 224
            +   ++ ++ GH+H      + G  +    +TC
Sbjct: 195 -RGSDIRSIIAGHLHYSTTATFAGIPVSVASATC 227


>UniRef50_B5JAZ3 Ser/Thr protein phosphatase family protein n=2 Tax=Rhodobacteraceae
           RepID=B5JAZ3_9RHOB
          Length = 274

 Score = 75.5 bits (184), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 58/217 (26%), Positives = 93/217 (42%), Gaps = 9/217 (4%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           +IL +TD HL     + ++G++     Q  L+A      +   ++  GDL     +  Y 
Sbjct: 3   KILVLTDLHLRGAG-KTIIGLDPTARLQQALDAALGDHPDARALILMGDLTHSGRAEEYD 61

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISP---AKRVFIGEQWQILLLDSQVF 132
              + +     P  ++ GNHD +    +A  +A ++P    +R+      +I+ LD+   
Sbjct: 62  KLRDLLHDCPIPVTYMLGNHDQRTRFCAAFPEATVTPQGHVQRIIDLAHHRIITLDTHDA 121

Query: 133 GVP---HGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
                  G L   +L WL+  LA A  R  L+  HH P P G   +D  +L N  EL   
Sbjct: 122 AANPAHSGRLCAGRLAWLDAALAGAGGRMALVFAHHPPHPVGLPGMDAIALVNGDELLDR 181

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQ 226
           L   P   +L CGH+H+ +     G       STC Q
Sbjct: 182 LRAAP--AHLFCGHVHRTISGQARGVAFTMFKSTCHQ 216


>UniRef50_Q20ZN1 Metallophosphoesterase n=1 Tax=Rhodopseudomonas palustris BisB18
           RepID=Q20ZN1_RHOPB
          Length = 252

 Score = 75.1 bits (183), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 64/232 (27%), Positives = 104/232 (44%), Gaps = 8/232 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++I+ I D HL  +  E + G +T ++++     I P     DL+V  GD+A + S   Y
Sbjct: 1   MKIIVINDLHLVPEG-ELVRGQDTNKAFECGWREIAPLVECADLVVVNGDVAHNASVEGY 59

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV--FIGEQWQILLLDSQVF 132
           + F       ++  +   GNHD +  +   L  A +     V         ++LLD+ V 
Sbjct: 60  RRFRRATQEIKSKLMVTVGNHDDRERLAIELGAAHLDNTGYVQAAHHAAASVVLLDTLVP 119

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGE-LDTVLA 191
           G P G L   +L WL  +L  A ER  + ++HH PL  G   LD+ +L +  + L  +L+
Sbjct: 120 GRPEGALCAVRLAWLREQLDLAAERPVIAIMHHPPLNLGVDALDEVALLDGCDALLELLS 179

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGW 243
           +      LL GH H    +  +GR    +   C  F    + F L   AP +
Sbjct: 180 RRSAPVTLLAGHHH----ISASGRIGPISYCICPAFSGPPARFGLWGHAPNF 227


>UniRef50_C7MAF7 Predicted phosphohydrolase n=1 Tax=Brachybacterium faecium DSM 4810
           RepID=C7MAF7_BRAFD
          Length = 284

 Score = 74.7 bits (182), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 66/230 (28%), Positives = 109/230 (47%), Gaps = 24/230 (10%)

Query: 15  VRILQITDTHLF---AQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
           +R+L +TDTHL+   A +H     ++T  + + +L+ +   + + D +V TGD ++D ++
Sbjct: 1   MRLLHLTDTHLYGDPAARHYDR--IDTAAALRGLLDRLGTLR-DIDAVVHTGDASEDGTA 57

Query: 72  AAYQHFAEGI----ASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKR--------VFIG 119
            +Y+   E +    AS  AP   + GNHD      SA+    + P +R        V + 
Sbjct: 58  QSYRLLHEILDPFAASLDAPLAVVMGNHDV-----SAVYGETVVPGERLPAAQDRVVPLP 112

Query: 120 EQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHS 179
              ++++LDS V G  +G L+  QL+WL  +LA      ++L +HH PL A  + L    
Sbjct: 113 RDGRLIVLDSSVPGAGYGHLAPEQLDWLREQLAVPAAGGSVLAIHHPPLVAATALLRGLD 172

Query: 180 LRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKP 229
           L     L  VLA    V  +L GH H E+  +  G  +   P       P
Sbjct: 173 LDGLDALAAVLAGS-DVSIVLSGHYHHEMSGEIAGIPVHVAPGITNVVDP 221


>UniRef50_A9CKB5 Putative uncharacterized protein n=2 Tax=Alphaproteobacteria
           RepID=A9CKB5_AGRT5
          Length = 266

 Score = 74.7 bits (182), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 57/195 (29%), Positives = 92/195 (47%), Gaps = 5/195 (2%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++I+QITDTHL      A+ GV+     +A +  I     + DL+V TGDL       AY
Sbjct: 1   MKIIQITDTHLLPPG-IAINGVDPENQLRAAVADIVEKHADADLLVMTGDLCNYGEPEAY 59

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSAL--QDAGISPAKRVFIGEQW-QILLLDSQV 131
           +   + +A    P   + GNHD +P   +A   Q    +   + FI  ++ ++L LDS  
Sbjct: 60  ELLRDILAPVSIPTRLMLGNHDRRPEFVAAFPEQPRDDNGYIQSFIDTEFGRLLFLDSHE 119

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
             V  G     +L WLE  L  A +    + +HH P+  G    +   + + G +   LA
Sbjct: 120 ADVIGGIYGADRLTWLENALESAGDLPITVFVHHPPMDCGIRHFEHIGMHDDGAIMRRLA 179

Query: 192 KFP-HVKYLLCGHIH 205
             P  +++++ GHIH
Sbjct: 180 AHPAGIRHIVFGHIH 194


>UniRef50_A5FYX3 Metallophosphoesterase n=1 Tax=Acidiphilium cryptum JF-5
           RepID=A5FYX3_ACICJ
          Length = 274

 Score = 74.3 bits (181), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 73/231 (31%), Positives = 105/231 (45%), Gaps = 21/231 (9%)

Query: 11  GEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQS 70
           G   + + Q +D HL A    A   V T         A        D +V TGDLA    
Sbjct: 6   GAPPLLVAQFSDLHLRAPGLTANRIVETNMLAARAFAAFAALAPAPDALVITGDLADRGE 65

Query: 71  SAAYQHFAEGIAS-FRAPCVWLPGNHDFQPAMYSALQD-------AGIS-PAKRVFIGEQ 121
           + AY+  A  I    R P + +PGNHD + AM + L D       AG++ PA+ + +   
Sbjct: 66  AEAYRLLAGLIERHVRVPVILIPGNHDDRAAMRATLGDRLAADDEAGVNRPAEHLPV--- 122

Query: 122 WQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLR 181
            ++L LDS + G  HG L + QL +L  +LA  P R   +LLHH P+  G + +D  ++ 
Sbjct: 123 -RLLPLDSTIGGESHGRLGDGQLRFLRDRLAADP-RPAAILLHHPPIATGIAHMD--AIG 178

Query: 182 NAGELDTVLAKFPH---VKYLLCGHIHQELDLDWNGRRLLATPSTC--VQF 227
                    A  PH   V  L CGH+H+ +     G  ++  PS    VQF
Sbjct: 179 LENAAALEAAIAPHAARVAGLWCGHVHRMIHGRLAGAPVVIAPSVAHQVQF 229


>UniRef50_Q2J948 Metallophosphoesterase n=5 Tax=Actinomycetales RepID=Q2J948_FRASC
          Length = 287

 Score = 73.9 bits (180), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 60/197 (30%), Positives = 90/197 (45%), Gaps = 11/197 (5%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           ++QI+DTH+  +       V+T+ + + VL+ I     +   ++ TGDLA      AYQ 
Sbjct: 16  LIQISDTHIVREGELMHGKVDTYAALRTVLDQIEASTLKIGALLLTGDLADRGDLLAYQR 75

Query: 77  FAEGI----ASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQW----QILLLD 128
             + +    A    P ++  GNHD +      L   G  P         W    +I++LD
Sbjct: 76  LRDLVEPAAARLGTPVLYGVGNHDSRGPFREGLL--GAEPTAEAHDYVHWVGDLRIIMLD 133

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           +   G   G LS  QL WL  +LA A    T+L LHH P+P+  + ++   L     L  
Sbjct: 134 TTEPGEHSGFLSTAQLRWLADELATAAPDGTILALHHPPVPSPLAMVNSLLLAEPQNLAD 193

Query: 189 VLAKFPHVKYLLCGHIH 205
           VLA    VK +L GH H
Sbjct: 194 VLAG-SDVKIVLAGHAH 209


>UniRef50_B6R8M8 Ser/Thr protein phosphatase family protein n=1 Tax=Pseudovibrio sp.
           JE062 RepID=B6R8M8_9RHOB
          Length = 272

 Score = 73.9 bits (180), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 53/213 (24%), Positives = 94/213 (44%), Gaps = 5/213 (2%)

Query: 19  QITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFA 78
           Q+TD H+ A    A   V+T    +  +  +   + + D +V +GDL    ++  Y+ F 
Sbjct: 5   QLTDIHIKAGGKFAYNCVDTLSHLRKAVAHLNTFRPQLDFVVISGDLVDLGNADEYELFR 64

Query: 79  EGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFI----GEQWQILLLDSQVFGV 134
           + I     P   +PGNHD + AM  A  D G    +         +  +I+ LD+ + G 
Sbjct: 65  QEIDQLTMPFYVIPGNHDHRDAMREAFADHGYLSKEGALQFSIEKDGLRIIGLDTTIPGK 124

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL-RNAGELDTVLAKF 193
             G     +  WL  +L    ++ TL+ +HH P   G   +D   L R   +   V+   
Sbjct: 125 HDGHFDADKQAWLRAELTAHKDQPTLVFMHHPPFKTGIEHMDDIMLMRADDDFWPVVTGQ 184

Query: 194 PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQ 226
             +  + CGH+H+ +++  NG  +   P++  Q
Sbjct: 185 SQILQIACGHVHRAIEVFKNGIPVSICPASGHQ 217


>UniRef50_D2EUB1 Metallophosphoesterase n=1 Tax=Bacteroides sp. D20
           RepID=D2EUB1_9BACE
          Length = 245

 Score = 73.2 bits (178), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 59/246 (23%), Positives = 108/246 (43%), Gaps = 12/246 (4%)

Query: 20  ITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAE 79
           ++D HL  Q    + G +T E +   ++ I+  Q + D I+ +GD++ D S ++Y     
Sbjct: 1   MSDLHL-TQDGSTIWGEDTREKFIIAIDMIKKMQ-DIDAILVSGDISNDGSFSSYIFADR 58

Query: 80  GIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVF------- 132
             +S   P  W  GNHD    + +    +         I   WQI++L+S V        
Sbjct: 59  LFSSTNIPTYWSLGNHDNLDLLKNNNLLSYCKLVCEATI-YGWQIIILNSIVHDEEQPGK 117

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
               G +    +  ++ K+    ++ T+++LHH  L  G  W D   L+N  +   ++  
Sbjct: 118 NRSRGVIDIDTMIKIKNKIY-TLKKPTIVVLHHPALEIG-GWQDLKILKNRDKFREIIES 175

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADG 252
             +V+ +L GHIH+  D   NG R    P     F    SN+ +   A G+  + ++ + 
Sbjct: 176 SEYVRIVLAGHIHEFTDRTLNGIRYSTAPGLGFAFSSKLSNYEIQHGAEGFNLITINKNK 235

Query: 253 TLTTEV 258
            L  ++
Sbjct: 236 ILINKI 241


>UniRef50_B7QYI4 3',5'-cyclic-nucleotide phosphodiesterase, CpdA n=1 Tax=Ruegeria
           sp. R11 RepID=B7QYI4_9RHOB
          Length = 275

 Score = 72.8 bits (177), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 61/245 (24%), Positives = 100/245 (40%), Gaps = 21/245 (8%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++++ ++D H   Q    +LG +      A ++ I  H  +    V +GD+A+  ++  Y
Sbjct: 11  MKLIWMSDLHF--QHSGEILGHDPQLRLDAAIDYINQHHSDASYCVISGDMAETATARNY 68

Query: 75  QHFAEGIASFRAPCVWLPGNHD--------FQ---PAMYSALQDAGISPAKRVFIGEQWQ 123
              A+ +     PC+ + GNHD        FQ     M   LQ +  +PA          
Sbjct: 69  ADLADRLDQLAIPCLPMVGNHDDRDLLRAQFQVPDSCMDGFLQYSVDTPAGL-------- 120

Query: 124 ILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNA 183
           IL LD+   G   GE    +  WL   L  A +R  LL LHH P+P G    D   L + 
Sbjct: 121 ILCLDTLKPGASEGEFCAERARWLTSTLDAAQDRAVLLFLHHPPMPLGLPVQDSARLEHG 180

Query: 184 GELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGW 243
                ++    ++++L  GH+H+ +     G    A  S   Q  P    +  ++  P  
Sbjct: 181 ARFLEIIEGRANLRHLCVGHVHRSVTGTIRGIPFTALRSVLYQAPPPQPEWDWNSFTPSA 240

Query: 244 RTLEL 248
              EL
Sbjct: 241 EAPEL 245


>UniRef50_Q9V2G8 Predicted phosphohydrolase, putative n=3 Tax=Pyrococcus
           RepID=Q9V2G8_PYRAB
          Length = 505

 Score = 72.4 bits (176), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 52/194 (26%), Positives = 95/194 (48%), Gaps = 13/194 (6%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
           ++ I  I+DTH+  +          ++SY   L A   +   FDL++ TGD+  +     
Sbjct: 3   KMLIAHISDTHITNEV--------AFKSYAYDLIANEINTRPFDLVIHTGDVTNNGLREE 54

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFG 133
           Y+H +  +     P +  PGNHD +   Y   +   I P   V+  +   I+ LDS +  
Sbjct: 55  YEHASYLLKKIEKPLIVAPGNHDARNVGYELFEKY-IGPLIGVYEFKDGVIIWLDSTIPD 113

Query: 134 VPHGELSEFQLEWLERKLAD-APERHTLLLLHHHPLPAGCSWLDQHSLRNAGE-LDTVLA 191
           +  G +  ++ +WL+ KL + + ++  ++  HHH +P   +  +++ L NAG+ LD +L+
Sbjct: 114 LSDGRVGGYKFKWLKAKLEEYSHKKIKIVAAHHHLVPLPDTGRERNVLFNAGDVLDLLLS 173

Query: 192 KFPHVKYLLCGHIH 205
               V   +CGH H
Sbjct: 174 H--DVTLYMCGHKH 185


>UniRef50_A4EV76 3',5'-cyclic-nucleotide phosphodiesterase, cpdA n=1 Tax=Roseobacter
           sp. SK209-2-6 RepID=A4EV76_9RHOB
          Length = 266

 Score = 72.4 bits (176), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 61/252 (24%), Positives = 112/252 (44%), Gaps = 10/252 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++++ ++D H  A  +  +LG +     +A +  I     E    + TGDL +      Y
Sbjct: 5   LKLIWLSDLHFLATGN--VLGHDPRLRLEAAISHISACYPEAAACIITGDLVESAEPEHY 62

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV---FIGEQWQILLLDSQV 131
           +     +++     + L GNHD +  +        ++ A+ V       +  ++ LD+ V
Sbjct: 63  EALQTQLSNLPGQLLPLTGNHDDRDLLRQVFSLPNVAMAEFVQYRVDFPRLSVVALDTLV 122

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
            G  +G L   +LEWL++ L D  +   LL +HH P+  G   LD+ +LRN  EL  +L 
Sbjct: 123 SGQGYGFLCAQRLEWLQQTLDDCRDGPLLLAMHHPPMKLGLPILDEDNLRNGQELLELLK 182

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHC-----SNFTLDTIAPGWRTL 246
              ++++LL GH+H+ +     G     + S   Q  P        +F+    AP +  +
Sbjct: 183 GRNNIQHLLLGHVHRPVAGLTAGIPFKTSKSILYQAPPAVPAWDWESFSPAPEAPAYTVI 242

Query: 247 ELHADGTLTTEV 258
           E+   G    E+
Sbjct: 243 EVTETGVTLQEM 254


>UniRef50_Q982B7 Mll9148 protein n=1 Tax=Mesorhizobium loti RepID=Q982B7_RHILO
          Length = 325

 Score = 71.2 bits (173), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 53/170 (31%), Positives = 72/170 (42%), Gaps = 3/170 (1%)

Query: 57  DLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV 116
           D++V TGDLA       YQ   E       P     GNHD +    +   +         
Sbjct: 84  DMMVVTGDLADSGQIGEYQLLKELTEGLPFPVHLALGNHDIRENFLAVFPEKKGPGGFVQ 143

Query: 117 FIGE--QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSW 174
           F  E  + +++ LD+ V G   G L   +L +L   L + P   TL+LLHH P   G   
Sbjct: 144 FCVEHDKLRVIGLDTLVEGEGLGRLCSERLSYLRDCLQERPNTSTLILLHHPPFAFGGGI 203

Query: 175 LDQHSLRN-AGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPST 223
            D   L + A EL  ++     V  LLCGH H+ +D  WNG      PS 
Sbjct: 204 YDAVRLIDGARELGEIITANKQVVRLLCGHHHRAIDCLWNGTLASVAPSV 253


>UniRef50_C6VLV6 3',5'-cyclic-nucleotide phosphodiesterase n=3 Tax=Lactobacillus
           plantarum RepID=C6VLV6_LACPJ
          Length = 290

 Score = 70.9 bits (172), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 65/201 (32%), Positives = 94/201 (46%), Gaps = 14/201 (6%)

Query: 15  VRILQITDTHLFAQKHEALLG--VNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA 72
           ++++QI+D HL       + G   + W     +++ IR      DLIV TGDL  D S+ 
Sbjct: 10  LQVIQISDLHLTPHGQVPVHGQQYDPWGKLANIIDDIRRLPTMPDLIVFTGDLIHDGSAD 69

Query: 73  AYQHFAEGI----ASFRAPCVWLPGNHDFQPAMYSAL--QDAGISPAKRVFIGEQWQILL 126
            YQ     +    A F      + GNHD + A Y      D G   A R+ IG       
Sbjct: 70  DYQRLHAIVHTMEAEFDCHVRVILGNHDRRAAFYEGYLPADPGPYYASRMRIGNN-DFYF 128

Query: 127 LDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHS--LRNAG 184
           LDS+V G   G L+  QL+WL + L  AP +   L L HHPL  G +  + H   L+N  
Sbjct: 129 LDSKVSGYEAGWLAPQQLQWLGKHLRQAPTKRAFLFL-HHPL-DGPTMTNMHYAILQNTP 186

Query: 185 ELDTVLAKFPHVKYLLCGHIH 205
            L +VL +  ++  +  GH+H
Sbjct: 187 ALLSVL-RGHNLGGVFSGHVH 206


>UniRef50_A3W656 Ser/Thr protein phosphatase family protein n=3 Tax=Rhodobacteraceae
           RepID=A3W656_9RHOB
          Length = 265

 Score = 70.5 bits (171), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 65/234 (27%), Positives = 101/234 (43%), Gaps = 24/234 (10%)

Query: 16  RILQITDTHLF-------AQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQD 68
           R L ++D H+         Q   A L     ++    L+AI P     D ++ TGD++ D
Sbjct: 3   RFLHLSDLHVVPEGQLVSGQLDTARLLRLAIDTLTTRLDAIGP----VDAVLVTGDISDD 58

Query: 69  QSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQD-AGISPAKRVF----IGEQWQ 123
            S+ +Y+     +       + +PGNHD +    +A  D   + P   +     IG+  +
Sbjct: 59  GSTESYEIARRDLMRLGHRLLVVPGNHDGRETFRAAFSDLPEMRPTGLIDWIADIGDT-R 117

Query: 124 ILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNA 183
           ++ LD+ + G   G L +  L  L   L+ A  R TL+ LHH PL  G  ++D   L N 
Sbjct: 118 VIGLDTLIEGKGGGVLRDESLALLSEALSTAGGRQTLVALHHPPLRTGLRFMDAIGLENP 177

Query: 184 GELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLD 237
             L  VL +      +L GH+H        GR  + T  +C      CS F LD
Sbjct: 178 NALRIVLDQHDAPVRVLAGHVHGVYH-GLLGRHPVVTAPSC------CSAFALD 224


>UniRef50_Q28NL1 Metallophosphoesterase n=2 Tax=Rhodobacteraceae RepID=Q28NL1_JANSC
          Length = 277

 Score = 70.5 bits (171), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 60/204 (29%), Positives = 90/204 (44%), Gaps = 14/204 (6%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           + L  TD H+     E ++G++    +Q  L        +   IV  GDL      A Y 
Sbjct: 7   KALIFTDLHI-TPPGETIIGLDPLARFQEGLAHALSRHPDAQHIVLLGDLTHTGDPAEYA 65

Query: 76  HFAEGIASFRAPCVWLPGNHDFQP----AMYSALQDAGISPAKRVFIGEQWQILLLDSQV 131
                +A    P     GNHD +     A  +AL   G +   R       ++L+LD+  
Sbjct: 66  RLVPALADCPIPLTVTMGNHDLRDHLRNAFPTALNPDGFAQTARDL--GPLRLLILDTHD 123

Query: 132 FG--VP---HGELSEFQLEWLERKLADAPE--RHTLLLLHHHPLPAGCSWLDQHSLRNAG 184
           +    P    G L E +L WL+ +LA A +  +  ++  HH P P G   +D   L NA 
Sbjct: 124 YDNQAPLEQDGWLCETRLAWLDAELARAADDGKDVVVFAHHPPCPVGFWAMDAIGLANAD 183

Query: 185 ELDTVLAKFPHVKYLLCGHIHQEL 208
            L + L   PHVK+L+CGHIH+ +
Sbjct: 184 ALLSRLHAAPHVKHLICGHIHRTI 207


>UniRef50_A3WHQ7 Putative cAMP phosphodiesterase n=1 Tax=Erythrobacter sp. NAP1
           RepID=A3WHQ7_9SPHN
          Length = 294

 Score = 70.1 bits (170), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 62/223 (27%), Positives = 95/223 (42%), Gaps = 19/223 (8%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           V I QITDTH+  +  EA      +  ++ VL  +   +   D+++ +GDL       +Y
Sbjct: 8   VLIAQITDTHVGFEP-EAGENEFNFVRFRNVLGHLLNQKILPDMLILSGDLTDGGQPDSY 66

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFI-------GEQWQILLL 127
               E +A    P   +PGNHD +  +  A  D   +     F        G   ++L L
Sbjct: 67  ARIRELVAECPFPVHVIPGNHDSRDELLKAFPDCPTADGFAQFAIDCDDGAGNALRVLCL 126

Query: 128 DSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGEL- 186
           DS   G   G   E +  WL ++LA  P+  T++ +HH P+ AG  W+D       GE  
Sbjct: 127 DSFEPGRHGGAFCEVRAAWLAKELAAHPDTPTVIFMHHPPVVAGIDWMDP----KPGEAW 182

Query: 187 -----DTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTC 224
                DTV      +  +  GH+H+ L     G  L  TP+  
Sbjct: 183 FKRFHDTVKGH-DQIISIQAGHLHRPLHSVVEGIPLSVTPAVA 224


>UniRef50_Q8TVF8 Predicted calcineurin superfamily phosphohydrolase n=1
           Tax=Methanopyrus kandleri RepID=Q8TVF8_METKA
          Length = 270

 Score = 69.7 bits (169), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 51/196 (26%), Positives = 90/196 (45%), Gaps = 19/196 (9%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWES---YQAV--LEAIRPHQHEFDLIVATGDLAQDQS 70
           +I+ I+D H+   +        +W     Y+ +  +  +RP     D+++ TGDL  +  
Sbjct: 4   KIVHISDLHISPYR-------KSWSPEVFYRGIEQINDLRP-----DVVIVTGDLTDNGL 51

Query: 71  SAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQ 130
              Y+  +  +    AP V +PGNHD +   +   +D      +   +     ++ LDS 
Sbjct: 52  VREYEEVSSLLEKIEAPVVPVPGNHDARNLGWMTFEDVFGDRYRVERVSADLYVVGLDSS 111

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERH-TLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
              V +G+L   + EWLE  L   P      + +HHH LP   +  +++ L +AGE+  +
Sbjct: 112 EPDVDYGQLGRERQEWLEETLRRIPGGACKCIAMHHHLLPVPGAGRERNVLVDAGEMINL 171

Query: 190 LAKFPHVKYLLCGHIH 205
             K+  V  +LCGH H
Sbjct: 172 CIKY-GVDLVLCGHRH 186


>UniRef50_C6BIA6 Metallophosphoesterase n=2 Tax=Ralstonia pickettii
           RepID=C6BIA6_RALP1
          Length = 284

 Score = 69.3 bits (168), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 63/224 (28%), Positives = 99/224 (44%), Gaps = 16/224 (7%)

Query: 18  LQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHF 77
           LQ+TD H+      A   V++       +  I     + D IV TGDL    +   Y H 
Sbjct: 6   LQLTDLHIKRPGRLAYRRVDSAAYLARCVAHILAQPEKPDAIVLTGDLVDAGAPEEYAHL 65

Query: 78  AEGIASFRAPCV-WLP--GNHDFQPAMYSALQD-AGISPAK----RVF-----IGEQWQI 124
              +A   A  +  LP  GNHD + A   A  D     PA     R F     IG+  ++
Sbjct: 66  RAVLAPLDAAGIHMLPVLGNHDGRDAAREAFVDWLAPIPADAQDTRAFQYWTDIGDV-RL 124

Query: 125 LLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL--RN 182
           +++D+   G P G L   +L+WL   LA   +R T++ +HH P   G   +D  SL   +
Sbjct: 125 IVIDTLDTGHPGGRLGVQRLDWLAEALAHETQRPTVIAMHHPPFATGIGHMDVQSLAPED 184

Query: 183 AGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQ 226
                 ++    +V+ ++CGH+H+ +D+ + G      PS   Q
Sbjct: 185 IPAFAQIVRAAGNVERIICGHLHRSIDVRFAGTVASTCPSPAHQ 228


>UniRef50_C6B6U2 Metallophosphoesterase n=2 Tax=Rhizobium leguminosarum
           RepID=C6B6U2_RHILS
          Length = 250

 Score = 68.9 bits (167), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 67/219 (30%), Positives = 88/219 (40%), Gaps = 21/219 (9%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           + QI+D H        L  + T E     L+  RP     D++V TGDL  DQ    Y+ 
Sbjct: 3   VAQISDIH----AGPDLSSLRTLERAIGWLKTFRP-----DVLVVTGDLVNDQWRHGYRL 53

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAG-----ISPAKRVFIGEQWQILLLDSQV 131
            AE + S   P   LPGN D    M S L   G       P       +   +  +D  V
Sbjct: 54  VAENLRSLDCPVHLLPGNGDDVQLMRSELVAVGTWINATGPMHFRTAVDGLTLFGVDVTV 113

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
            G  +G++    L WL   LAD     +LL +H  PL  G   LDQ   RN   L + L 
Sbjct: 114 AGQSYGDVLP-HLPWLTSALADV-TTPSLLFMHQPPLRIGIEVLDQVGCRNGSALLSTLE 171

Query: 192 KFPHVKY-LLCGHIHQELDLDWNGRRLLATPSTCVQFKP 229
               +   +LCGH+H+       GR    T  TC    P
Sbjct: 172 TMHRLPLAILCGHVHRPA----FGRLGSMTVQTCGSLCP 206


>UniRef50_C7D8R5 Phosphodiesterase n=1 Tax=Thalassiobium sp. R2A62
           RepID=C7D8R5_9RHOB
          Length = 292

 Score = 68.6 bits (166), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 59/225 (26%), Positives = 94/225 (41%), Gaps = 15/225 (6%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           + L  TD H+     E ++ ++        L     H  +   ++  GDL      + Y 
Sbjct: 27  KYLIFTDVHIVGAG-ETIIDLDPAVRLTQGLAHAVHHHPDAKAVIIAGDLTHHGLPSEYT 85

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFI------GEQWQILLLDS 129
             AE +     P   + GNHD++P+       A   P    F+      G+   IL LD+
Sbjct: 86  RLAEVLDECPLPVHVMLGNHDYRPSFRKVFTQA---PDVDGFVQFAIHDGDHV-ILCLDT 141

Query: 130 QVFGVP---HGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGEL 186
           +    P    G L E +L+WL   L    ++   L+ HH     G + +D+  L N  E 
Sbjct: 142 KDQTAPDHHSGLLCETRLDWLAAHLETHADKQVTLIAHHPAFDTGFTGMDRIKLHNGAEF 201

Query: 187 DTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHC 231
             ++A+ P VK L+ GH+H+ +    NG  +    STC Q  P C
Sbjct: 202 RDLIAQHPCVKQLIHGHVHRTIMGQTNGVAVAMLKSTCHQI-PMC 245


>UniRef50_A9DXP9 Putative uncharacterized protein n=1 Tax=Oceanibulbus indolifex
           HEL-45 RepID=A9DXP9_9RHOB
          Length = 268

 Score = 68.2 bits (165), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 60/206 (29%), Positives = 95/206 (46%), Gaps = 12/206 (5%)

Query: 16  RILQITDTHL-FAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           R + +TD H+     ++  L  +T  + + V+E I     + D +VA+GDL       +Y
Sbjct: 3   RFVHLTDLHISHPDLNDPHLQSDTPATLRRVVEVINGMAPQPDFVVASGDLTNQGDQQSY 62

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQ--WQILLLDSQVF 132
           +   + + +  AP V   GNHD + A ++A+   G++ A       Q    ++ LDS V 
Sbjct: 63  ELLRDILGTMHAPLVLALGNHD-KRAGFNAVFAPGLADAPYFHDAPQGDLHVITLDSSVP 121

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPL--PAGCSW--LDQHSLRNAGELDT 188
           G   G L + Q E+L   L   PE   LL++HH P   P   +W  LD+ S     E   
Sbjct: 122 GKVAGALDDAQFEFLGAALQRHPELAKLLVIHHPPRVDPEALAWGSLDEASSARLAE--- 178

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNG 214
            + K   V  +L GH+H      W+G
Sbjct: 179 -MLKGQRVAGVLSGHVHVNRVSHWHG 203


>UniRef50_A6U5M4 Metallophosphoesterase n=3 Tax=Rhizobiaceae RepID=A6U5M4_SINMW
          Length = 268

 Score = 67.4 bits (163), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 47/210 (22%), Positives = 93/210 (44%), Gaps = 14/210 (6%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           +++  +D H+  +    ++G++        +  +     + DL++  GDLA      +Y+
Sbjct: 3   KLIIFSDLHMVPEG-GTIIGLDPHRRLANGIAHVNRFHADADLVIFAGDLAHAADRESYE 61

Query: 76  HFAEGIASFRAPCVWLPGNHD----FQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQV 131
                +     P   + GNHD    F      A+ DA     + +   +   ILL    +
Sbjct: 62  RLQALLRELMPPAALMIGNHDRRELFLDVFAEAVTDANGFVQQAIDFPDCRAILL--DTL 119

Query: 132 FGVPH-------GELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAG 184
           F  P+       G L + +L WL+R+L +A +R  L+ +HH P  +G + +D   L N  
Sbjct: 120 FAPPYDYPVSHAGHLCQTRLAWLDRQLGEAGDRPALIFMHHPPHASGFAGMDMIRLVNED 179

Query: 185 ELDTVLAKFPHVKYLLCGHIHQELDLDWNG 214
           E   ++ +  +V+++  GH+H+ +     G
Sbjct: 180 EFYALVKRHGNVRHIFAGHVHRTISGSSRG 209


>UniRef50_A5FX65 Metallophosphoesterase n=1 Tax=Acidiphilium cryptum JF-5
           RepID=A5FX65_ACICJ
          Length = 282

 Score = 67.4 bits (163), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 69/238 (28%), Positives = 102/238 (42%), Gaps = 12/238 (5%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           I  I+D H+      A   V T    + VL  +       + IV TGDL        Y+ 
Sbjct: 3   IAHISDLHVRPVGRPANRVVETNMMAERVLRRVATLDPAPEAIVITGDLVDCGRDDEYEE 62

Query: 77  FAEGIASFRAPC--VWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQ-----WQILLLDS 129
               +   + PC    +PGNHD + A  +AL       A   F+        +++++LDS
Sbjct: 63  LNR-LLDRKLPCPVYVVPGNHDRREAFRAALGHLPGVTADPDFVQYSADIGPFRLIMLDS 121

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
            V G  HGEL   +L +L+  L  A  R  L+ LHH P+  G + +D   LR++  L   
Sbjct: 122 VVPGAGHGELCPQRLAFLDAALEAAAGRKVLIGLHHPPVITGVAAMDSIMLRSSEALLAR 181

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLE 247
            A   +V  +L GH H+ +     G  LL+ P+       H S  T D  A  +  LE
Sbjct: 182 AAAHGNVAAILSGHHHRAIHAAHGGTMLLSVPAAAG----HQSEITFDPKARAYFHLE 235


>UniRef50_C5CDX7 Metallophosphoesterase n=1 Tax=Kosmotoga olearia TBF 19.5.1
           RepID=C5CDX7_KOSOT
          Length = 358

 Score = 66.2 bits (160), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 51/191 (26%), Positives = 90/191 (47%), Gaps = 15/191 (7%)

Query: 37  NTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHD 96
           N+  ++  ++E I  +  E   +V TGD+  D S   Y  F + ++  + P + +PGNHD
Sbjct: 63  NSISTFGKIIEQINTNP-EITFVVNTGDMVFDGSVTKYNFFLKQLSKLQKPFIPVPGNHD 121

Query: 97  F-QPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAP 155
                M + ++  G  P    F  +Q   ++LDS         +  +Q++WLE +L ++ 
Sbjct: 122 IADGGMNNYVEFFG--PLYYAFAVDQVYFIVLDSS----NEETIGAWQMKWLEEQLKNSQ 175

Query: 156 ERHTLLLLHHHPLPAGCSWLDQ---HSL---RNAGELDTVLAKFPHVKYLLCGHIHQELD 209
           +     +  H P+      +D+   HSL   +NA EL  +L K+ +V  +  GHIH    
Sbjct: 176 KHKYRFVFLHVPIFDPRLPMDKQPGHSLKNTKNAMELLKLLQKY-NVTMVFAGHIHGYFR 234

Query: 210 LDWNGRRLLAT 220
            +W G   + T
Sbjct: 235 GEWEGVPYIVT 245


>UniRef50_A3K5W8 Phosphodiesterase n=1 Tax=Sagittula stellata E-37
           RepID=A3K5W8_9RHOB
          Length = 249

 Score = 66.2 bits (160), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 53/233 (22%), Positives = 94/233 (40%), Gaps = 11/233 (4%)

Query: 35  GVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGN 94
           G++ ++     L  I  H  +   +V +GDL +     AY    + +     P   + GN
Sbjct: 5   GLDPYDRLARALGHIAEHHRDAGFVVISGDLTEYAEREAYARLRQALTMLPMPVRLMMGN 64

Query: 95  HDFQPAMYSALQDAGISPAKRVFIG---EQWQILLLDSQVFGVPHGELSEFQLEWLERKL 151
           HD +   +   +D        V       + + +  D+   G   G     +L WL  +L
Sbjct: 65  HDDRDVFFDVFRDHPRDADGYVNHATDLREGRFIFCDTVETGRDEGHFGPGRLRWLTEQL 124

Query: 152 ADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGE---LDTVLAKFPHVKYLLCGHIHQEL 208
           A   ER   L  HH+PL  G    D +SLR+  +    D + A    V Y+  GH+H  L
Sbjct: 125 AGC-ER-AFLFFHHNPLHIGDPSADGYSLRDEDQGPLRDLLKANAQKVAYMFFGHVHAPL 182

Query: 209 DLDWNGRRLLATPSTCVQFKPHCS---NFTLDTIAPGWRTLELHADGTLTTEV 258
               +G      PST +Q  P+ +   +  +  + P +R + +  +  +  ++
Sbjct: 183 CGTMSGIAFSGVPSTMMQRIPNLTPAEHTAIGPLEPAYRVVLVRGEDVVIHQI 235


>UniRef50_C9CTH4 Phosphodiesterase n=6 Tax=Proteobacteria RepID=C9CTH4_9RHOB
          Length = 284

 Score = 66.2 bits (160), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 55/208 (26%), Positives = 86/208 (41%), Gaps = 14/208 (6%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++ + +TDTH+       L G N        +++I     + D  V TGDL     + AY
Sbjct: 1   MKFIHLTDTHVIGGD-RTLYGANPARRLALAVDSINAEHGDADFTVVTGDLTHWGDADAY 59

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYS-----ALQDAGISPAKRVFIGEQWQILLLDS 129
             F   I     P V + GNHD   A        A  + G   ++R     Q   L LD+
Sbjct: 60  AAFEAQIRRLSMPLVLMVGNHDDTAAFARCFPEVARDEHGFVQSRRE--TSQGSCLFLDT 117

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
           +  G   G     +L WL ++L D       L +HH P   G S +D   + +      V
Sbjct: 118 KAPGTHAGGYCAQRLGWLRQQL-DESSGPVFLFMHHPPFRHGISSMDAIMMLDHHAFWRV 176

Query: 190 LAKFPH---VKYLLCGHIHQELDLDWNG 214
           +   PH   +++L  GH+H+ +  +W G
Sbjct: 177 IE--PHRARIRHLFFGHVHRAIFGNWRG 202


>UniRef50_B7BFD3 Putative uncharacterized protein n=1 Tax=Parabacteroides johnsonii
           DSM 18315 RepID=B7BFD3_9PORP
          Length = 238

 Score = 65.9 bits (159), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 56/250 (22%), Positives = 108/250 (43%), Gaps = 20/250 (8%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWES-----YQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
           +RI+ I+D HL  + H    G+  W +     +   ++ I+      D I+ +GDL+ D 
Sbjct: 1   MRIIHISDIHL--ENH----GLPIWNTDTKLHFDKAIKKIQT-MDNIDAIIISGDLSNDG 53

Query: 70  SSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDS 129
           S+ +Y +    +A    P    PGNHD     Y +   +       +F+   W  ++L+S
Sbjct: 54  SAWSYNYIDNLLAKTNIPTFCCPGNHDNLDIFYGS-HKSWFYKNCELFMLNGWTFIMLNS 112

Query: 130 QVFGVPHGELSEFQLEWLE-RKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
            + G   G    +  ++L+  K +  P   T+++LHH P+     WL++  L N    + 
Sbjct: 113 VMAGKSRGNF--YPDKFLDLLKHSCGP---TVIVLHHPPIEQD-GWLNRKLLENRDVFND 166

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLEL 248
           ++ K+ +++ +L GH H       +G    +  S    F P    F +     G+  + L
Sbjct: 167 IIHKYKNIRLVLYGHTHHHEIKTIDGIIYSSASSIGFAFHPKLLKFQIAHGREGFSLITL 226

Query: 249 HADGTLTTEV 258
           +    +   +
Sbjct: 227 NDSNIIIENI 236


>UniRef50_B3Q702 Metallophosphoesterase n=5 Tax=Alphaproteobacteria
           RepID=B3Q702_RHOPT
          Length = 274

 Score = 65.9 bits (159), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 52/199 (26%), Positives = 90/199 (45%), Gaps = 9/199 (4%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++++ ++D HL       + G N   +++  L  I    H+ +L+V TGDL+    +  Y
Sbjct: 1   MKLIHLSDIHL-TTPGGTIGGRNPRLNFERALTHILRDHHDAELMVITGDLSDWGDAEDY 59

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSAL----QDAGISPAKRVFIGEQWQILLLDSQ 130
           +     + +F  P     GNHD +    S       D G+   + V      + LLLD+ 
Sbjct: 60  RWLKAQLGAFPIPVRLCIGNHDRRENFLSVFPEFADDDGL--VQGVCDTPAGRCLLLDTA 117

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
             G   G   E +  WL R+LA+ P    LL +HH+P+P     +DQ  L + G    ++
Sbjct: 118 EAGTHAGRYCETRRAWLTRQLAEHPGPF-LLFMHHNPMPTHLGPMDQIRLLDDGAFGQIV 176

Query: 191 AKF-PHVKYLLCGHIHQEL 208
            +    ++++  GH H  L
Sbjct: 177 GRHRDRIRHIFFGHCHLPL 195


>UniRef50_A9FYQ8 Phosphodiesterase n=6 Tax=Rhodobacteraceae RepID=A9FYQ8_9RHOB
          Length = 276

 Score = 65.5 bits (158), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 64/256 (25%), Positives = 107/256 (41%), Gaps = 15/256 (5%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++I+ I+D HL     E + G++    +   L  +  +    D IV TGDL      AAY
Sbjct: 1   MKIIHISDIHLTIPGEE-MGGLDPHARFSRALANVAENHANADRIVITGDLTHWGEVAAY 59

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE---QWQILLLDSQV 131
           +     +A    P   L GNHD +        D  +     V   E   + +++ LDS  
Sbjct: 60  EALKSALAEVSIPVRLLIGNHDDRDTFRKVFTDHPVDANGFVNHAETLDETRLIYLDSVG 119

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL--RNAGELDTV 189
                G     + +WL+ +L  A      + LHH+P+P G    D+ +L   +      +
Sbjct: 120 DKTHAGHFCAVRRDWLKAELTAAGR--ARIFLHHNPMPVGLPAEDKIALVPEDRAAFKAL 177

Query: 190 LAKF-PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTL---DTIAPGWRT 245
           L  +   + Y+  GH+H  +   + G    + PST  Q  P  +   L     +AP +  
Sbjct: 178 LEAYGDRIDYIHFGHVHAPIHGRFAGIPFASVPSTGNQSLPDLNETELLKGAPMAPAYFV 237

Query: 246 LELHADGTLTTEVHRL 261
           L +  DG  TT +H++
Sbjct: 238 LSI--DGNDTT-IHQI 250


>UniRef50_C5EL28 Predicted protein n=1 Tax=Clostridiales bacterium 1_7_47FAA
           RepID=C5EL28_9FIRM
          Length = 288

 Score = 65.5 bits (158), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 47/155 (30%), Positives = 73/155 (47%), Gaps = 11/155 (7%)

Query: 56  FDLIVATGDLAQDQSSAAYQ----HFAEGIASFRAPCVWLPGNHDFQPAMYSA-LQDAGI 110
            DL+V TGDL +D ++  Y+    H  E +     P V   GNHD + +     L++ G 
Sbjct: 73  IDLVVITGDLTEDGTAEDYRCLKHHIRERVGDI--PLVVTLGNHDNKRSFREGWLEEMGS 130

Query: 111 SPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPA 170
           +P   +       ++  D+ V GVP G + + Q  WLER L       ++L+ HHH LP 
Sbjct: 131 APYNTIRWVGGTAVIAFDTSVQGVPDGRMDDRQAAWLERALDAVGRNPSILVTHHHLLPE 190

Query: 171 GCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIH 205
                    L  +G+L +++     V  +LCGH H
Sbjct: 191 QGQI---PPLPESGKLLSLIGN-SGVCLILCGHTH 221


>UniRef50_C9AD97 Phosphoesterase n=3 Tax=Enterococcus casseliflavus
           RepID=C9AD97_ENTCA
          Length = 270

 Score = 65.5 bits (158), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 60/216 (27%), Positives = 93/216 (43%), Gaps = 40/216 (18%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIR-------------PHQHEFDLIVA 61
           + +L I+D H      E+ L     E YQ +L A++               +   DL+V 
Sbjct: 1   MNVLHISDIHF----RESYLPCE--EGYQGMLAAMQNPLIPLEECIQDAKARAAIDLVVI 54

Query: 62  TGDLAQDQSSAAY----QHFAEGIASFRAPCVWLPGNHDF-----QPAMYSALQDAGISP 112
           +GDL +D + A Y    Q+  +   S   P V   GNHD      Q     +++ A  +P
Sbjct: 55  SGDLTEDGAPADYASLKQYLEKAFGS--VPIVVTLGNHDIKRHFRQGWQGKSVETASDTP 112

Query: 113 AKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGC 172
             +V+  E   I+  D+  +G   G + E Q EWL+  LA   E+  + + HHH LP   
Sbjct: 113 FNQVYETETLAIVTFDNSCYGYADGIVDERQFEWLQATLAQLKEKKIVFVTHHHLLP--- 169

Query: 173 SWLDQHSL---RNAGELDTVLAKFPHVKYLLCGHIH 205
              DQ S      A  L  +L ++  +  +L GH H
Sbjct: 170 ---DQASTPAWAGANRLVALLQQY-QISCILSGHTH 201


>UniRef50_A9CI50 Putative uncharacterized protein n=1 Tax=Agrobacterium tumefaciens
           str. C58 RepID=A9CI50_AGRT5
          Length = 291

 Score = 65.1 bits (157), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 60/212 (28%), Positives = 93/212 (43%), Gaps = 14/212 (6%)

Query: 14  RVRILQITDTHL-FAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA 72
           RV  + +TD H+   Q  +  L   T  +  A L  ++      + IV +GDL     + 
Sbjct: 4   RVNFVHLTDLHIGNPQVQDDDLYSETSATLSATLAQVKALVPPPEFIVVSGDLTNRGDAG 63

Query: 73  AYQHFAEGIAS--FRAPCVWLPGNHDFQPAMYSALQD--AGIS-PAKRVFIGEQWQILLL 127
           +Y+     +A     AP ++  GNHD +   Y  + D   G+  P     +     I+++
Sbjct: 64  SYEELKRLMAEAELDAPVLFALGNHDRRDGFYPVMLDRHEGVDEPYDHAEVIAGIHIIVM 123

Query: 128 DSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPL----PAGCSWLDQHSLRNA 183
           D+ V G   G     Q+EWLE +L + PE   LL++HH P          W +  S  + 
Sbjct: 124 DTSVPGKVGGAFEPGQIEWLEEELENHPELPKLLVMHHAPALDFDRPEAEW-ESLSFDDT 182

Query: 184 GELDTVLAKFPH-VKYLLCGHIHQELDLDWNG 214
             LD +L  F H V  +L GHIH +    W G
Sbjct: 183 EALDELL--FEHDVIGILAGHIHCDRMSHWQG 212


>UniRef50_B5K790 Metallophosphoesterase n=1 Tax=Octadecabacter antarcticus 238
           RepID=B5K790_9RHOB
          Length = 265

 Score = 63.5 bits (153), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 57/218 (26%), Positives = 89/218 (40%), Gaps = 17/218 (7%)

Query: 31  EALLGVNTWESYQAVLE-AIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCV 89
           + ++G++     Q  L+ A+R H     LI+  GDL     +  Y    + +     P  
Sbjct: 8   KTIIGLDPTVRLQQSLDTALRDHPDAKALIL-MGDLTHSGRAEEYDILRDMLQDCPIPVT 66

Query: 90  WLPGNHDFQPAMYSALQDAGISP---AKRVFIGEQWQILLLDSQVFGVP---HGELSEFQ 143
           ++ GNHD +    +    A ++P    +R+      +I+ LD+          G L   +
Sbjct: 67  YMLGNHDQRAPFRATFPTAPVTPQGHVQRIVDLPHHRIITLDTHDAAANPAHSGLLCADR 126

Query: 144 LEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGH 203
           L WL+  LA A  R  L+  HH P   G   +D  +LRN  +L   L   P   +L CGH
Sbjct: 127 LAWLDAALAGAGGRMALVFAHHPPHAVGLPGMDAIALRNGDDLLDRLRATP--AHLFCGH 184

Query: 204 IHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAP 241
           +H+ +     G            FK  C    LD I P
Sbjct: 185 VHRTISGQTRGVAF-------TMFKSTCHQAPLDLIRP 215


>UniRef50_D0L6V7 Metallophosphoesterase n=1 Tax=Gordonia bronchialis DSM 43247
           RepID=D0L6V7_GORB4
          Length = 245

 Score = 63.2 bits (152), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 53/188 (28%), Positives = 84/188 (44%), Gaps = 11/188 (5%)

Query: 43  QAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMY 102
           ++ L  I       D ++ TGDLA + S++ Y+  A G+     P +   GNHD +    
Sbjct: 23  ESTLSYINARADGIDALLITGDLADEGSASEYRE-AYGVLESPLPMLITAGNHDVRENFS 81

Query: 103 SALQDAGISP----AKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERH 158
           +AL D   S     ++R  IG+    L+ DS + G   G LS+  L W+  ++    +  
Sbjct: 82  AALLDHETSEPLNWSQR--IGDVL-FLVADSSIAGRNDGYLSDDTLTWMADEITMHGDET 138

Query: 159 TLLLLHHHPLPAGCSWLDQHSLRNAGE--LDTVLAKFPHVKYLLCGHIHQELDLDWNGRR 216
            +L+  HHP P   S     S+R  GE  L  ++ + P++   LCGH H      +  R 
Sbjct: 139 PVLIAFHHP-PVKLSMPFMDSIRQTGEDRLAALVGRHPNIVAFLCGHAHTPAVTRFADRP 197

Query: 217 LLATPSTC 224
           L   P   
Sbjct: 198 LCIAPGVA 205


>UniRef50_A3JT02 Putative uncharacterized protein n=1 Tax=Rhodobacterales bacterium
           HTCC2150 RepID=A3JT02_9RHOB
          Length = 271

 Score = 62.4 bits (150), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 50/208 (24%), Positives = 90/208 (43%), Gaps = 13/208 (6%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           +IL ++D HL    ++ ++G+N  E  ++ L+       + D ++  GDL        ++
Sbjct: 3   KILLLSDLHLRG-PNQKIIGINPMERLKSALDHALACHPDADRLILLGDLTHSGKVLEFE 61

Query: 76  HFAEGIASFRAPCVWLPGNHD----FQPAMYSALQDAGISPAKRVFIGEQWQILL--LDS 129
                      P  +  GNHD    F+    +   D        + IG+   ++L  LD 
Sbjct: 62  RLKSLTDQCPIPVTFTLGNHDNRDHFRNVFANVEPDENGHIQSVIDIGDYRMVVLDTLDG 121

Query: 130 QVFGVPH--GELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELD 187
             F   H  G+    +  WL++++A A  R  L+ +HH P+  G   +D   L +    +
Sbjct: 122 PPFRNYHHSGKYCAARQSWLDQQIATAEGRKILIFMHHPPMDVGFPGMDAIKLADG---N 178

Query: 188 TVLAKFPH-VKYLLCGHIHQELDLDWNG 214
             L ++ H   +L CGHIH+ +    NG
Sbjct: 179 AFLKRYAHKATHLFCGHIHRTISGTTNG 206


>UniRef50_B9XC60 Metallophosphoesterase n=1 Tax=bacterium Ellin514
           RepID=B9XC60_9BACT
          Length = 303

 Score = 62.4 bits (150), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 69/253 (27%), Positives = 107/253 (42%), Gaps = 39/253 (15%)

Query: 20  ITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLA-QDQSSAAYQHFA 78
           ++D HL A + +   G+N  +++  V   +   +     ++ +GDLA     SA Y    
Sbjct: 45  VSDIHLAADRKKLGRGINMADNFTQVTTQLLDPKWRHSAMLISGDLAFNSGESADYATVT 104

Query: 79  EGIASFRA---PCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQIL--------LL 127
           E +   +A   P     GNHD +   + A+ +A    AKR     Q  +L        +L
Sbjct: 105 ELLQPVQAGGIPIHLTLGNHDNREHFWDAIAEA--KAAKRPVTDHQVSLLRSSRANWFVL 162

Query: 128 DS--QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHH-----PLPAGCSWLDQHSL 180
           DS  Q    P G + E QL+WL   L D   +  L+++HH+       P+G        L
Sbjct: 163 DSLEQTLATP-GLIGEAQLDWLAHALDDNKRKPALIVVHHNLNDNSGKPSG--------L 213

Query: 181 RNAGELDTVLAKFPHVKYLLCGHIHQ-ELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTI 239
           ++  +L  ++    HVK LL GH H  E+  D +G  L+  P T   FK    N      
Sbjct: 214 KDGDKLLDIIRPRKHVKALLYGHSHDWEVKQDSSGIHLINLPPTAYVFKEGKPN------ 267

Query: 240 APGWRTLELHADG 252
             GW    L + G
Sbjct: 268 --GWVHASLQSKG 278


>UniRef50_C6VU97 Metallophosphoesterase n=1 Tax=Dyadobacter fermentans DSM 18053
           RepID=C6VU97_DYAFD
          Length = 244

 Score = 61.2 bits (147), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 62/236 (26%), Positives = 100/236 (42%), Gaps = 18/236 (7%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           RI QITD HL  ++  A  G +T  + + +L+ +         I+ TGD+    + A+YQ
Sbjct: 3   RIAQITDIHLM-EEWSAQNGADTDTNLKLILQDVGARG--IRDIIFTGDIG---NPASYQ 56

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQ---WQILLLDSQVF 132
            F   +  F    +  PGNHD    +    Q A +     +F   +   ++ + LDS   
Sbjct: 57  RFFALMKDFDFTII--PGNHDKFADIRPHYQPAYLEGKSEMFHAVEETHFKYIFLDSSSD 114

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
            V     SE QL WLE +L     RH LL +HH  L    +   ++ L N   +  +L +
Sbjct: 115 SV-----SEMQLRWLENELVTT--RHVLLFIHHPVLQVLTAVDFKYPLLNRAAVKELLVR 167

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLEL 248
                 +  GH H +            TP+  VQ + +     + +   G+R +EL
Sbjct: 168 SDREITIFSGHYHTDDFTKEENLTQYVTPAASVQMEKNPLEIVVHSRYYGYRIIEL 223


>UniRef50_A1ZMS0 Putative uncharacterized protein n=1 Tax=Microscilla marina ATCC
           23134 RepID=A1ZMS0_9SPHI
          Length = 221

 Score = 60.8 bits (146), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 59/248 (23%), Positives = 110/248 (44%), Gaps = 32/248 (12%)

Query: 15  VRILQITDTHLFAQKH-EALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
           +RI+QITD +L A  H   +L +  +E+   +L  I    H  DL++ T ++ Q + +  
Sbjct: 5   IRIVQITDPYLLANIHYPEVLPIQVFEN---ILTHINLLPHPPDLLILTSEVLQQRRNDT 61

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFG 133
            +     +     P  W+              Q+A  +     FI       +L+S    
Sbjct: 62  LR----LLQRLDIPFYWVAHE-----------QNASFNVKGTHFI-------MLNSCSKN 99

Query: 134 VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKF 193
              G L    L++L+  L ++     ++ L HHPL        + +L++AG+  ++L +F
Sbjct: 100 HSQGYLGNDTLDFLQNDLENSWAYPCIVTLRHHPLAIRTLTPPKDTLKDAGQFLSILDQF 159

Query: 194 PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGT 253
            H+K +L GHIH +  L+ N     A+P+ C    P   N     +   +R L+L ++G 
Sbjct: 160 YHIKAVLFGHIHHDFMLERNDIWFFASPAIC----PISPNNP--AVVFQYRLLDLTSEGE 213

Query: 254 LTTEVHRL 261
           +   + ++
Sbjct: 214 VEVSLMKV 221


>UniRef50_C6D6T3 Metallophosphoesterase n=1 Tax=Paenibacillus sp. JDR-2
           RepID=C6D6T3_PAESJ
          Length = 273

 Score = 60.8 bits (146), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 56/202 (27%), Positives = 93/202 (46%), Gaps = 15/202 (7%)

Query: 14  RVRILQITDTHLFAQK-HEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA 72
           +++ + +TDTH+ A          N  +  + V E I+        +V TGDL  + +  
Sbjct: 3   KLKFVHLTDTHMNAPGVDNPFAKFNLADKVKRVFEHIKTASVSPAFVVITGDLTHEGNVQ 62

Query: 73  AYQHFA----EGIASFRAPCVWLPGNHDFQ-PAMYSALQDAGISPAKRVFIG----EQWQ 123
            Y++      EG A    P   + GNHD + P     L++    P+++ +      +  +
Sbjct: 63  DYEYIRTIVDEGSALLGVPVHVVLGNHDHRAPFREGFLKE---EPSEQAYYYSHTIQGVR 119

Query: 124 ILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNA 183
           ++ L+SQV G  HGE+   QL WLE  L+   E  T++ L HHP+         H L N 
Sbjct: 120 LIGLNSQVKGQHHGEIDAEQLAWLEDTLSTPAENGTIVAL-HHPMLNINGMPADHVLANR 178

Query: 184 GELDTVLAKFPHVKYLLCGHIH 205
            +L  VL +   V  ++ GH+H
Sbjct: 179 DQLGNVL-EGTDVIGVVAGHVH 199


>UniRef50_A4EJU5 3',5'-cyclic-nucleotide phosphodiesterase, cpdA n=2
           Tax=Rhodobacterales RepID=A4EJU5_9RHOB
          Length = 262

 Score = 60.8 bits (146), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 47/194 (24%), Positives = 84/194 (43%), Gaps = 5/194 (2%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           +I+ ++D H   Q    + G++     +A +  +  H  + D  V TGDL  D     Y 
Sbjct: 3   KIIWMSDPHF--QMTGTIDGLDPRVRLKAAITYLNTHYTDADFAVLTGDLVGDDIVEDYT 60

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSAL---QDAGISPAKRVFIGEQWQILLLDSQVF 132
             AE +A  +     L GN+D + +  + L    D      + V        + LD+   
Sbjct: 61  GIAEYLAKSQVSIYPLMGNNDERESFRAHLPLPADGMPDFIQYVVDTPDQTFICLDTHKV 120

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
           G   G+    +  WL++ LA  P +   + +HH PL  G    D+  L ++     +++ 
Sbjct: 121 GSHAGQFCSARQAWLDQVLAKDPLKPAYIFMHHPPLNLGLPPQDEIMLEDSDAFLDIVSA 180

Query: 193 FPHVKYLLCGHIHQ 206
             +VK+L  GH+H+
Sbjct: 181 HNNVKHLFMGHVHR 194


>UniRef50_C8QH10 Metallophosphoesterase n=3 Tax=Enterobacteriaceae
           RepID=C8QH10_9ENTR
          Length = 240

 Score = 60.5 bits (145), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 54/197 (27%), Positives = 87/197 (44%), Gaps = 18/197 (9%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           + QI+D H           +  ++   A L+ + P     D++V TGDL  +Q  A Y  
Sbjct: 3   VAQISDIHASPDNDN----LQRFDKALAWLDQLNP-----DVLVLTGDLIDNQWLAGYAL 53

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV----FIGEQWQILLLDSQVF 132
            AE ++  + P   LPGN D +  M +     G + A       +     ++L LDS + 
Sbjct: 54  IAERLSQKKWPSRVLPGNSDDRRQMRAVW---GATAADEFLHFNYDAGDLRLLGLDSTLV 110

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
           GV  G +    + WLE++L D      LL LHHH   +G   LD+       EL  ++  
Sbjct: 111 GVTAGSVVN-HIAWLEQQLRDIHTSPALLFLHHHVFASGIPSLDKTMCAGVPELAALIRH 169

Query: 193 FP-HVKYLLCGHIHQEL 208
            P  +  +  GH+H+ +
Sbjct: 170 MPGKLLAIASGHVHRPI 186


>UniRef50_A3U194 Putative uncharacterized protein n=1 Tax=Oceanicola batsensis
           HTCC2597 RepID=A3U194_9RHOB
          Length = 287

 Score = 60.5 bits (145), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 60/206 (29%), Positives = 93/206 (45%), Gaps = 10/206 (4%)

Query: 18  LQITDTHLFAQKHEA-LLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           + +TD H+ A   E  +L  +T E+ +  LE I         IVA+GDL       AY+ 
Sbjct: 9   IHMTDLHVNASGVEDDMLFNDTRETLERTLEEIGRMDDAPAFIVASGDLTNRGDPEAYRT 68

Query: 77  FAEGIAS--FRAPCVWLPGNHDFQ---PAMYSALQDAGISPAKRVFIGEQWQILLLDSQV 131
            AE  A+     P ++  GNHD +    A +  L      P     + +   ++ LDS V
Sbjct: 69  VAEIFAASGLDIPVLFALGNHDKREGFAAAFPELYTDASQPFDHDRVIDGLHLITLDSSV 128

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPL-PAGCSWLDQHSLRNAG--ELDT 188
                G     Q++WL+ +LA  P+   LL++HH P+     S ++  SL      EL T
Sbjct: 129 PNEIGGYWEAGQIDWLKDRLAAHPDLPKLLVMHHAPMIDLTASDMEWESLSAVATEELRT 188

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNG 214
            +A    V  +L GH+H +    W+G
Sbjct: 189 AIAGHD-VVGILSGHVHMDRVAQWHG 213


>UniRef50_B5YAA1 Membrane-associated protein, putative n=2 Tax=Dictyoglomus
           RepID=B5YAA1_DICT6
          Length = 252

 Score = 60.5 bits (145), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 49/206 (23%), Positives = 89/206 (43%), Gaps = 10/206 (4%)

Query: 57  DLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHD-FQPAMYSALQDAGISPAKR 115
           D I+  GD+  + +   Y++  E + +   P   +PGNHD ++       Q     P   
Sbjct: 54  DFIIQLGDILVEGTEKEYKYIGELLRNVNIPFYIVPGNHDLYKDPRGEKFQKFTGRPLYY 113

Query: 116 VFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWL 175
            F  E  + ++L++       G L + QLEWL   L +  +++  + +H   +  G  +L
Sbjct: 114 YFDYENARFIILNNS-----SGILGKTQLEWLTNVLKENDKKYKFVFMHQPVISPGLFFL 168

Query: 176 DQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFT 235
              +     ++   L +   V Y+  GHIH     + NG  ++   S     +P+ S+  
Sbjct: 169 LHKADPVESKMLMKLFEEYKVNYVFSGHIHMYYRKEING--VVYIISGIGGARPYVSS-D 225

Query: 236 LDTIAPGWRTLELHADGTLTTEVHRL 261
           LD   P +  +E+  D  +  EV RL
Sbjct: 226 LDEGKPHFVLMEV-TDKGIKEEVVRL 250


>UniRef50_A1SEE2 Metallophosphoesterase n=2 Tax=Actinobacteria (class)
           RepID=A1SEE2_NOCSJ
          Length = 313

 Score = 60.5 bits (145), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 66/229 (28%), Positives = 93/229 (40%), Gaps = 24/229 (10%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           +  ++D HL A        ++T    +  L  +   +     +V TGDLA     AAY  
Sbjct: 13  VAHLSDPHLLAGGARQYGVIDTEAGLRLALTRLSRLETPPHALVFTGDLADKAEPAAYSR 72

Query: 77  FAEGI----ASFRAPCVWLPGNHD----FQPAMYSALQDAGISPAKRVFIGEQWQILLLD 128
             E +    A   A  VW+ GNHD    +   ++        +P  RV      +I+ LD
Sbjct: 73  LRELVEPAAAEMGAAVVWVMGNHDERAPYARGLFGVEGADADAPQDRVHEVAGLRIVALD 132

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAG-------CSWLDQHSLR 181
           + V G  HGEL++ QL WL   LA      TLL LHH P+P            LDQH L 
Sbjct: 133 TSVPGYHHGELADDQLAWLAEVLATPAPHGTLLALHHPPIPIPMMPAAEIIELLDQHRLA 192

Query: 182 NA-GELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKP 229
           +  G  D        V+ +L GH H      + G  +    +TC    P
Sbjct: 193 DVLGGTD--------VRCILGGHFHYSTYSTFAGIPVSVASATCYTSDP 233


>UniRef50_B4D428 Metallophosphoesterase n=1 Tax=Chthoniobacter flavus Ellin428
           RepID=B4D428_9BACT
          Length = 303

 Score = 60.1 bits (144), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 63/251 (25%), Positives = 106/251 (42%), Gaps = 23/251 (9%)

Query: 20  ITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQD----QSSAAYQ 75
           ++DTH+ A    A   VN  +  +  +  +R        ++  GD A +    +  A + 
Sbjct: 45  LSDTHVAADATLARFDVNMADHLRNAVAGVRALSSPPAGVIVNGDCAFNHGLAEDYATFT 104

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISP----AKRVFIGEQWQI--LLLDS 129
                ++    P     GNHD +   ++A++DA  +P    +++V I E       +LDS
Sbjct: 105 GLLHPLSEAGLPLHLSLGNHDDREVFWNAIKDARQTPPPLASRQVSIVEAGHANWFMLDS 164

Query: 130 -QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
             V     G L + Q  WL + L    ++  L+++HH P+        +  L +  EL  
Sbjct: 165 LDVTNKTPGVLGDEQRAWLSKALDARTDKPALVVVHHDPMLIEGK---KTGLLDTAELLA 221

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLEL 248
           +L    HVK L+ GH H     D +G  L+  P+    FK             GW   +L
Sbjct: 222 ILKPRSHVKALIFGHTHTWRLTDHDGLHLVNLPAVGYPFKKEEVT--------GWVDCQL 273

Query: 249 HADGTLTTEVH 259
            ADG ++ E+H
Sbjct: 274 RADG-MSLEMH 283


>UniRef50_O27755 Transcriptional regulator Icc related protein n=1
           Tax=Methanothermobacter thermautotrophicus str. Delta H
           RepID=O27755_METTH
          Length = 262

 Score = 60.1 bits (144), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 52/193 (26%), Positives = 88/193 (45%), Gaps = 14/193 (7%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           +I QI+D H   +     L  N        LE   P     DLI+ +GDL  +  S  Y+
Sbjct: 4   KIAQISDVHFGEKNFSDQLRKNLLHQ----LENENP-----DLIIVSGDLTTEGYSHEYE 54

Query: 76  HFAEGIASFRA--PCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFG 133
             A  +   R       +PGNHD +       +   I   K V    ++ ++ LDS    
Sbjct: 55  LAAAFVDELRTITSTYTIPGNHDARNVGLIHFEKL-IGRRKFVHHDSEFAVIGLDSSEPD 113

Query: 134 VPHGELSEFQLEWLERKLADAPERH-TLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
           +  G++   QL+WL ++L   P+    ++  HHH LP   +  +++ L ++G+L  +L +
Sbjct: 114 INDGQIGMDQLDWLRKELERVPDHLCKIVTFHHHLLPIPNTGRERNILLDSGDLLKLLKE 173

Query: 193 FPHVKYLLCGHIH 205
           +  V ++L GH H
Sbjct: 174 YG-VDFVLNGHKH 185


>UniRef50_A5UK60 Predicted phosphohydrolase, calcineurin-like superfamily n=2
           Tax=Methanobrevibacter smithii RepID=A5UK60_METS3
          Length = 247

 Score = 59.3 bits (142), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 47/191 (24%), Positives = 88/191 (46%), Gaps = 12/191 (6%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           I+ I+D H+     E     + +    A + AI P     D+I+ TGDL  +   + +  
Sbjct: 4   IVHISDLHISELGFEE----DVFIKAVAEINAINP-----DMIILTGDLTNNGYYSEFIQ 54

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPH 136
             + +  F AP   +PGNHD +   Y   ++     + ++   +++ ++ LDS    +  
Sbjct: 55  ATKYLEMFDAPLFAVPGNHDARNLGYETFEELIGECSWKLTKDDEFVVIGLDSSSPDISS 114

Query: 137 GELSEFQLEWLERKLADA--PERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
           G +   Q  W+E +L      E  +++ LHHH +P   +  +++ L +AG++   L    
Sbjct: 115 GNVGRPQHLWMEHQLDQCVIEELFSIVALHHHVIPIPKTGRERNVLTDAGDVLKTLTDH- 173

Query: 195 HVKYLLCGHIH 205
            V  +L GH H
Sbjct: 174 EVDLVLAGHKH 184


>UniRef50_A6CD50 Cyclic 3',5'-adenosine monophosphate phosphodiesterase n=1
           Tax=Planctomyces maris DSM 8797 RepID=A6CD50_9PLAN
          Length = 301

 Score = 58.5 bits (140), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 61/213 (28%), Positives = 87/213 (40%), Gaps = 19/213 (8%)

Query: 59  IVATGDLA-QDQSSAAYQHFAEGIASFRAPCV---WLPGNHDFQPAMYSALQDAGIS--P 112
           ++  GDLA +D     Y+HFA  I   +   +      GNHD +   Y  +Q+   S  P
Sbjct: 80  VLINGDLALRDGQPGDYRHFASLIQPLQEAKIDTHLTLGNHDERDVFYEVMQEQRPSAPP 139

Query: 113 AKRVFIG----EQWQILLLDS-QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHP 167
            K   I     +     LLDS     V  G L + Q  WL   L    ++  +++ HH+P
Sbjct: 140 VKSRHISVVQTKFANFFLLDSLHKTMVTQGTLGKEQRSWLANALDAHADKPAIIVTHHNP 199

Query: 168 LPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQF 227
              G        L ++ EL  +L   P VK  + GHIH   +    G  +L TP+T    
Sbjct: 200 RLGGDPVHFPGGLTDSEELWELLVSRPQVKAYIHGHIHDRGNAQHKGIHILNTPATSYVA 259

Query: 228 KPHCSNFTLDTIAPGWRTLELHADG-TLTTEVH 259
            P       D    GW   +L   G TLTT  +
Sbjct: 260 NP-------DHSTTGWTIAQLTPTGVTLTTRTN 285


>UniRef50_B1LAV7 Metallophosphoesterase n=2 Tax=Thermotoga sp. RQ2
           RepID=B1LAV7_THESQ
          Length = 343

 Score = 58.5 bits (140), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 47/191 (24%), Positives = 85/191 (44%), Gaps = 18/191 (9%)

Query: 37  NTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHD 96
           N+  ++  +++A+   Q+     V TGD+  D S   ++ + E +  F+ P + +PGNHD
Sbjct: 49  NSISTFSKLIDAVNREQNA-AFAVNTGDMVFDGSLFKWELYLEQLRRFKIPVLPVPGNHD 107

Query: 97  F--QPAMYSALQDAGISPAKRVF-IGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLAD 153
               P  Y  +      P    F  G  + I+L ++         +  +QLEWL+++L  
Sbjct: 108 LADDPGNYLKI----FGPLYYSFHTGNSYFIVLNNAN-----EKYVDAYQLEWLKKELEK 158

Query: 154 APE-RHTLLLLH---HHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELD 209
           +   R+  + +H   + P            L NA  L  +L ++ +V  +  GHIH    
Sbjct: 159 SQSYRYRFVFMHVPVYDPRKEKQPGHSMKDLENAQTLLNILKEY-NVTMVFAGHIHGYFR 217

Query: 210 LDWNGRRLLAT 220
            +WNG   + T
Sbjct: 218 GEWNGVSYIIT 228


>UniRef50_C7NWB5 Metallophosphoesterase n=1 Tax=Halomicrobium mukohataei DSM 12286
           RepID=C7NWB5_HALMD
          Length = 312

 Score = 58.2 bits (139), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 50/197 (25%), Positives = 82/197 (41%), Gaps = 30/197 (15%)

Query: 53  QHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDF-------QPAMYSAL 105
           + + D +++ GDL +D     Y    E ++    P   +PGNHD         P    A 
Sbjct: 59  RRDVDAVLSPGDLTKDGEPWNYDAVDEALSELDVPFYAVPGNHDVPKVRDEHDPLSVEAF 118

Query: 106 QDAGISPAKRVFIGEQWQILLLDSQVFGVP-------HGELSEFQLEWLERKLADAPERH 158
            D    P +  +  E   + ++     G          G ++E  L+WL+  LA+A    
Sbjct: 119 ADR-YGPGELPYHAEVGGLDVIGLNTAGTADRLYESHEGRVTEATLDWLDETLAEA---E 174

Query: 159 TLLLLHHHPLPAGCSWLDQH-----------SLRNAGELDTVLAKFPHVKYLLCGHIHQE 207
           T ++L HH LP+    +D H           ++ +A  L   LA     + LL GH H  
Sbjct: 175 TPVVLLHHNLPSVSDQIDAHREIEPEMVEIPAMADADPLAETLADG-GAQLLLSGHYHLP 233

Query: 208 LDLDWNGRRLLATPSTC 224
              +++G R +A P+TC
Sbjct: 234 ATGEYHGLREIAAPTTC 250


>UniRef50_B9TAV3 Putative uncharacterized protein n=1 Tax=Ricinus communis
           RepID=B9TAV3_RICCO
          Length = 279

 Score = 57.4 bits (137), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 53/213 (24%), Positives = 89/213 (41%), Gaps = 15/213 (7%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           I QI+D H  +  ++++  ++   S+ AVL+         DL+V +GDL        Y  
Sbjct: 39  IAQISDIHA-SPTNDSMARLDRAVSWLAVLQP--------DLLVVSGDLVDGNWLEGYGL 89

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGI---SPAKRVFIGEQWQILL-LDSQVF 132
            +  +       + LPGN D +  M + +         PA          +++ +D+ V 
Sbjct: 90  ISTSLHRLACRSLILPGNSDDRAVMRTIMPQPDYWHDRPAMHFIEPCGGSVIIGVDTCVD 149

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
           G  +G++++  L WL R LA +P    LL  HHH  P G   LD    +    L  +L  
Sbjct: 150 GEAYGDVTQ-HLSWLRRALAGSPNGTALLFTHHHVFPCGIPPLDAVMCKGTQALAGLLKS 208

Query: 193 FPHVKYLLC-GHIHQELDLDWNGRRLLATPSTC 224
                  +C GH+H+ +   + G       S C
Sbjct: 209 GIRPPAAICSGHVHRSMSSLFAGIPAYTCGSIC 241


>UniRef50_A6WWL5 Metallophosphoesterase n=1 Tax=Ochrobactrum anthropi ATCC 49188
           RepID=A6WWL5_OCHA4
          Length = 271

 Score = 57.0 bits (136), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 59/230 (25%), Positives = 90/230 (39%), Gaps = 23/230 (10%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA- 73
           VR++QI+DTHL   +H+A   V  W   +  L +  P      LI+ +GD++ D +    
Sbjct: 2   VRVIQISDTHL--GRHKAHF-VENWRPLKNWLASENP-----KLIIHSGDISVDGADVED 53

Query: 74  -YQHFAEGIASFRAPCVWLPGNHDF-------QPAMYSALQDAGISPAKRVFIGE--QWQ 123
            +    E +    AP + +PGNHD        QPA    L+          +  +   W+
Sbjct: 54  DFAFCREVMVDLPAPMLVVPGNHDVGEPQSAHQPANEHRLERWNRQYGADFWAKDVGNWR 113

Query: 124 ILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNA 183
           +L  DS +         E Q  WLER++  A  R      H      G   +D       
Sbjct: 114 LLGFDSMILSSGLAA-EEAQFHWLERQMESADGRRIAWFTHQPLFINGWEDIDNGYWSVK 172

Query: 184 GELDTVLAKFPH---VKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPH 230
            E  T L +      V  +  GH+H   D   +G + +  PS      PH
Sbjct: 173 REPRTRLQRLTQRFGVDLIASGHLHLSHDFILDGVQFVWCPSAAFAVGPH 222


>UniRef50_C0WNK1 3',5'-cyclic-nucleotide phosphodiesterase n=3 Tax=Lactobacillus
           RepID=C0WNK1_LACBU
          Length = 291

 Score = 57.0 bits (136), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 66/278 (23%), Positives = 111/278 (39%), Gaps = 31/278 (11%)

Query: 13  ARVRILQITDTHLF--AQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQS 70
            + +I+QI+DTHL     K      ++  E  + V + I     + DLIV +GDL  +  
Sbjct: 4   VQCKIVQISDTHLTPAGAKPANHQHLDPEEKLRTVFDDIYNTNVDPDLIVISGDLIHEGD 63

Query: 71  SAAYQHFAEGI----ASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQIL- 125
           +  Y  F   +        AP   + GNHD     Y          A R +  E  + L 
Sbjct: 64  AEVYADFHHMLDQEQERLMAPIKVILGNHDRTDQFYKGFL-GKKRVATRCYYHESLEGLE 122

Query: 126 --LLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNA 183
              LD++   +  G L + QL WL+ +L +  +R  ++ +HH         +    L+N 
Sbjct: 123 CYFLDTKCGDIEQGYLDQTQLHWLKNQLQEY-QRPGIIFMHHPLYGPPLQQMRYSILQNG 181

Query: 184 GELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSN----FTLDTI 239
            +L  V+    HVK +  GH+H       +G  +L   +    +  +C+N    F  D  
Sbjct: 182 DDLLNVI-DHTHVKAIFSGHVHFANSYVVDG--ILNVVADSTAYHINCANPHEHFVTDGT 238

Query: 240 APGWRTLELHAD-----------GTLTTEVHRLADTRF 266
           A  +  + +  D           GT T    ++ +T F
Sbjct: 239 A--YNVITVDGDDIGVEQRLLYLGTKTINAFKIPNTDF 274


>UniRef50_O66909 Putative uncharacterized protein n=1 Tax=Aquifex aeolicus
           RepID=O66909_AQUAE
          Length = 249

 Score = 56.2 bits (134), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 51/196 (26%), Positives = 91/196 (46%), Gaps = 18/196 (9%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++I  I+D H+  + +E  LG N  +     L A +P     DL++ TGDL      A Y
Sbjct: 1   MKIAHISDLHVKCEWYEDRLGNNLVK----YLNAQKP-----DLLIITGDLTDYGYYAEY 51

Query: 75  QH---FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILL-LDSQ 130
           +    F E I   +   V  PGNHD +   Y   ++      +  +  +++ +++ +DS 
Sbjct: 52  KRAYSFLELIEVEKRVVV--PGNHDARNEGYELFEE--FFGTRMPYYEDEYMVIIGMDSS 107

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
           +     G +     ++L   L D  ++  ++ LHHH +P   +  D   L +AG L  V+
Sbjct: 108 LPDREEGHIGRKGYKFLRETLKDKGDKLKIVALHHHVVPIPATGSDLAILTDAGNLMKVV 167

Query: 191 AKFPHVKYLLCGHIHQ 206
            +   V+ +L GH H+
Sbjct: 168 DELG-VELVLTGHKHK 182


>UniRef50_C2KF95 Serine/threonine protein phosphatase family protein n=4
           Tax=Lactobacillus crispatus RepID=C2KF95_9LACO
          Length = 408

 Score = 56.2 bits (134), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 47/193 (24%), Positives = 84/193 (43%), Gaps = 16/193 (8%)

Query: 86  APCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFG--------VPHG 137
           +P +W      F  + + AL +   S A  V + +Q++++L DS ++G        + +G
Sbjct: 125 SPAIW---KEIFADSYHYALHEDPDSLAYSVNLNKQYRLILADSNIYGKQESQTHLITNG 181

Query: 138 ELSEFQLEWLERKLADAPER--HTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPH 195
            +SE Q+ W+E++L DA ++    L  +HH+           + L NA  L  +L K+ +
Sbjct: 182 RISESQMNWIEKELIDAQQKQQQVLFFMHHNLYRHNKVIYQGYILDNALALQGLLQKY-N 240

Query: 196 VKYLLCGHIH-QELDLDWNGRRLLATPSTCV-QFKPHCSNFTLDTIAPGWRTLELHADGT 253
           VK +  GH+H Q +   +  R +      C    K       LD     ++      +  
Sbjct: 241 VKAVFSGHMHAQNIIGPFANRPIAEVAGACFCMTKQEYGQLYLDEAGMQYQVHSFKMESW 300

Query: 254 LTTEVHRLADTRF 266
           LT E  +   T F
Sbjct: 301 LTAEEKQKVPTDF 313


>UniRef50_C7Q3U3 Metallophosphoesterase n=3 Tax=Actinomycetales RepID=C7Q3U3_CATAD
          Length = 247

 Score = 55.8 bits (133), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 44/155 (28%), Positives = 71/155 (45%), Gaps = 10/155 (6%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           V I  ++D H+ A       G    E  + V + +     + DL+V TGD+A     + Y
Sbjct: 3   VVIAHVSDIHIDA-------GPRAAERTRRVFDHLDALPADLDLVVLTGDIADHGLDSEY 55

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSAL--QDAGISPAKRVFIGEQWQILLLDSQVF 132
           +   +  A+ R P +  PGNHD + A   AL    A   P  +V   +++ + L DS + 
Sbjct: 56  ETVRQATAT-RHPLLVCPGNHDDREAFRRALLGVPASTGPINQVHRTDRFVVALCDSSIP 114

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHP 167
               G L++  L WL  +L   P+   +L+  HHP
Sbjct: 115 KQDDGFLADETLAWLAAELDATPDGVPVLIGFHHP 149


>UniRef50_A1HNK3 Metallophosphoesterase n=1 Tax=Thermosinus carboxydivorans Nor1
           RepID=A1HNK3_9FIRM
          Length = 345

 Score = 55.8 bits (133), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 51/184 (27%), Positives = 79/184 (42%), Gaps = 24/184 (13%)

Query: 40  ESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQP 99
           + Y ++L+ I   + EF   V  GDL     +  Y+ F    A    P     GNHD Q 
Sbjct: 137 DVYLSLLDKINALRPEF--AVNGGDLVPAGRAGEYEQFLADSARLTIPYYTALGNHDIQG 194

Query: 100 ---AMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPE 156
               +Y+ L    ++P    F+      L+LD+       G++   QL WLE KL +   
Sbjct: 195 DGRTLYNRL----LAPNYYDFVWGNSLFLVLDNA-----DGDMDARQLAWLENKLKERTA 245

Query: 157 RHTLLLLHHHPL---PAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWN 213
           RHT +++H  P    P     ++   L  A  L  + A++  V  + C HIH    + + 
Sbjct: 246 RHTFIIMHKPPFDPRPGRSHTVNSREL--ADRLQNLAAQY-GVTAVFCSHIH----MYYQ 298

Query: 214 GRRL 217
           G RL
Sbjct: 299 GERL 302


>UniRef50_A6DDC8 Metallophosphoesterase n=1 Tax=Caminibacter mediatlanticus TB-2
           RepID=A6DDC8_9PROT
          Length = 113

 Score = 55.1 bits (131), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 29/109 (26%), Positives = 56/109 (51%), Gaps = 4/109 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +RI+Q+++ H+   ++  L G+N    +Q  +E+I  +  + + IV TGDLA   +  AY
Sbjct: 1   MRIIQLSELHIRGDEYN-LFGLNPLFRFQKAIESINKNYPDAEFIVITGDLAHKSNINAY 59

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQ 123
           +   E + + +     + GNHD +   YS  Q+    P +  F+   ++
Sbjct: 60  KQIKEIVNNSKIEVKLIIGNHDNRDDFYSVFQNV---PQQNGFVNYTYK 105


>UniRef50_A9DF72 Possible 3',5'-cyclic-nucleotide phosphodiesterase, cpdA n=1
           Tax=Hoeflea phototrophica DFL-43 RepID=A9DF72_9RHIZ
          Length = 278

 Score = 55.1 bits (131), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 63/272 (23%), Positives = 105/272 (38%), Gaps = 27/272 (9%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++++ I+D HL       +LG++   +++  L  +  H  + + IV TGDL       +Y
Sbjct: 1   MKLVHISDIHL---NEAPILGLDPVANFKRCLAYVEAHDADAERIVITGDLTHHGGEESY 57

Query: 75  QHFAEGIASF-----RAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQ------ 123
           +   + +A+       AP + L GNHD +    S        P   V    QW       
Sbjct: 58  RLLVDILAASPLQDKLAPRL-LIGNHDHRETFASVFSSTHRDPNGFV----QWTEETPAG 112

Query: 124 -ILLLDSQVFGVPHGELSEFQLEWLERKLADAPER--HTLLLLHHHPLPAGCSWLDQHSL 180
             + +D+   G   G   E ++ WL   L DA        L +HH+P+    +  D   +
Sbjct: 113 VFVYMDTVDQGRHGGRYCEARMAWLAGVLDDARSSGARAFLFMHHNPVRVNVANADIIGI 172

Query: 181 RNAGELDTVLAKFPHV-KYLLCGHIHQELDLDWNGRRLLATPST---C-VQFKPHCSNFT 235
            N  EL  +L ++  V  ++  GH H  L     G    A  ST   C   F    +   
Sbjct: 173 INERELQALLKRYNDVIAHMFFGHCHYSLSGSVAGISYSAPRSTNHPCWPDFSGMANRMG 232

Query: 236 LDTIAPGWRTLELHADGTLTTEVHRLADTRFQ 267
              +AP +    L  D  +   +  L   + Q
Sbjct: 233 FGELAPNYNVCFLRDDSIVVHTIDFLDAEKVQ 264


>UniRef50_A9A2N5 Metallophosphoesterase n=4 Tax=marine archaeal group 1
           RepID=A9A2N5_NITMS
          Length = 252

 Score = 54.3 bits (129), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 53/199 (26%), Positives = 87/199 (43%), Gaps = 29/199 (14%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           I+QI+D H+ +Q  E    V   E     +  + P     D+IV TGDL  +     Y+ 
Sbjct: 3   IVQISDLHIGSQFLEEKFDVLVSE-----VNELNP-----DVIVITGDLTNEGLMKEYEK 52

Query: 77  FAEGIASFRAP-CVWLPGNHDFQPAMYSALQDAGISPAKRVF----IGEQWQILLLDSQV 131
               +  F     + + GNHD++   Y           K+ F    + E    ++L +  
Sbjct: 53  CKSLLEKFNTKKIIAISGNHDYRNTGYLLF--------KKFFPFQTVNELDNDVVLVTVG 104

Query: 132 FGVP---HGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGE-LD 187
              P    GE+   Q  WLER +    ++  ++ +HHH +    +  DQ ++ +AG+ L 
Sbjct: 105 TARPDRNEGEVGYRQNLWLERTMKKYKDKIKIVAMHHHLIAIPDTGSDQLTVVDAGDVLR 164

Query: 188 TVLAKFPHVKYLLCGHIHQ 206
           TVL     V  +LCGH H+
Sbjct: 165 TVLD--SEVDVVLCGHKHR 181


>UniRef50_C2E1N9 Serine/threonine protein phosphatase family protein n=8
           Tax=Lactobacillus jensenii RepID=C2E1N9_9LACO
          Length = 414

 Score = 53.9 bits (128), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 59/256 (23%), Positives = 104/256 (40%), Gaps = 55/256 (21%)

Query: 4   LLTLPLAGEARVRILQITDTHL-----------FAQKHEALLGVNTWESYQAVLEAIRPH 52
           +L   L  +   +I  I+DTHL           F +     +G +     +A+L   R  
Sbjct: 1   MLKNLLTQKENPKIWVISDTHLIANELHDKGWAFQKMQNTSVGKDLHYQQKALLAFTRKV 60

Query: 53  QHEF-DLIVATGDLAQDQSSAAYQHFAEGIASFR---APCVWLPGNH------------- 95
             E  D++V TGD+  +    + Q FAE  A  R      + LPGNH             
Sbjct: 61  LKEKPDVVVVTGDITFNGERLSMQRFAEIFAPLRRHGIKLLVLPGNHDIYDGWARKFKDD 120

Query: 96  -----------DFQPAMYS-----ALQDAGISPAKRVFIGEQWQILLLDSQVFGVP---- 135
                      DF+   Y      A ++ G S A  V +   ++++L DS ++ +     
Sbjct: 121 VQYRTDQVSPQDFKEIFYDSSYRYAAREDGSSLAYSVNLSPNYRLILADSNIYPMEYSLT 180

Query: 136 ----HGELSEFQLEWLERKL--ADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
               HG + + +L ++E ++  A++  +H L  +HH+             L NA ++  +
Sbjct: 181 HPHTHGRIDDEELAFIEGQIIEAESNHQHVLFFMHHNLYRHNAVIYHNFVLDNASQVKRL 240

Query: 190 LAKFPHVKYLLCGHIH 205
             K+ +V+ +  GHIH
Sbjct: 241 FNKY-NVQAVFSGHIH 255


>UniRef50_D1B7Z2 Metallophosphoesterase n=1 Tax=Thermanaerovibrio acidaminovorans
           DSM 6589 RepID=D1B7Z2_THEAS
          Length = 278

 Score = 53.9 bits (128), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 58/218 (26%), Positives = 95/218 (43%), Gaps = 30/218 (13%)

Query: 1   MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV 60
           ++S+L+ P+ GE  +R L + DT                  ++ ++  +R  Q  F  ++
Sbjct: 40  LDSILSTPVEGE--LRFLVVGDTR------------GPGSRFRFLVPQMREDQGLF--VI 83

Query: 61  ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE 120
             GDL    +   Y+   E + S R P + + GNH+         +D   S   R F+  
Sbjct: 84  HLGDLTNRGTQGEYREALELLRSIRKPFLVVIGNHELVDRGRGRFEDIFGSWRDRAFVLG 143

Query: 121 QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPL----PAGCSWLD 176
              ++LLD+   G P   LSE +L WL+R+LA  P    + +  H PL    P     +D
Sbjct: 144 GALLVLLDN-ADGRP---LSEERLRWLDRELASHPGPKMVFM--HQPLFDPRPGKSHAMD 197

Query: 177 QHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNG 214
           +   R A E+  VL +   V  +   H+H     DW+G
Sbjct: 198 E---RGAREMLEVLKRH-RVDRVFASHVHAFFQGDWDG 231


>UniRef50_Q2JP63 Ser/Thr protein phosphatase family protein n=2 Tax=Synechococcus
           RepID=Q2JP63_SYNJB
          Length = 309

 Score = 53.9 bits (128), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 61/233 (26%), Positives = 88/233 (37%), Gaps = 56/233 (24%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTW---ESYQAVLEAIRPHQHEFD---LIVATGDLAQ 67
           R+   Q++D HL  +      G   W   +S +  LEA   H ++      +V TGDL  
Sbjct: 5   RICFAQVSDVHLMPET-----GCRCWWMSDSPRRQLEAAVAHLNQVPDLHFVVFTGDLVD 59

Query: 68  DQSSAAYQHFAEGIASFRAPCVWLPGNHDFQ--------------------------PAM 101
                ++Q F E +A  R P     GNHD                            P  
Sbjct: 60  QADPESFQSFQEIVAQLRVPYYLSLGNHDIDTLRRKGRFNRDQFIRWCQSQFPLSLAPTG 119

Query: 102 YSALQDAGISPAKRVFIGEQWQILLLDSQV--FGVPHGELSEFQLEWLERKLADAPERHT 159
           Y    D  +SP   +      +++ LD+ +  F +P G L   QL WL   L   PE   
Sbjct: 120 YV---DYSLSPLPGI------RLIALDASLGRFPLPQGVLRPSQLHWLGEHLQTVPEEWL 170

Query: 160 LLLLHHHPLPAGCSWLDQHSLRN-------AGELDTVLAKFPHVKYLLCGHIH 205
           +LL+H  P  A    +D    R        A  L  +LA+   V  +L GH+H
Sbjct: 171 ILLIHQPPFIAPTQ-MDAVLFRKYRLLSEPASALHALLARHGRVVAVLSGHLH 222


>UniRef50_C8XD18 Metallophosphoesterase n=1 Tax=Nakamurella multipartita DSM 44233
           RepID=C8XD18_NAKMY
          Length = 292

 Score = 53.5 bits (127), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 54/221 (24%), Positives = 89/221 (40%), Gaps = 9/221 (4%)

Query: 20  ITDTHLFA---QKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           ++D+HL +   + ++ L      +   AVL +        D ++ +GDL       AY+ 
Sbjct: 21  LSDSHLTSAGVRYNQVLDADAALDRAVAVLRSAVADGRPLDAVILSGDLTDTGDPDAYRR 80

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGI-SPAKRVFIGEQWQILLLDSQVFGVP 135
               +     P ++  GNHD +   + +L   G   P  +       ++L LDS + G  
Sbjct: 81  LRAAVEPLGVPVLYATGNHDVRTEFHRSLLGRGDEGPVLQSVQVGGLRMLALDSTIPGAG 140

Query: 136 HGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGEL---DTVLAK 192
           HG L+   L  L   LAD     T+++LHH PLP     L   +L  A  +   D +   
Sbjct: 141 HGRLTAEHLAELTAALADPAPEGTIVVLHHAPLPPPSPLLSYFALEAASRIALRDAIAGT 200

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSN 233
              V+ +L GH H           +    ST ++  P   N
Sbjct: 201 --DVRLVLAGHHHLAQSGTLGAIPVAVAGSTAIRTDPLAPN 239


>UniRef50_Q1AXD2 Metallophosphoesterase n=1 Tax=Rubrobacter xylanophilus DSM 9941
           RepID=Q1AXD2_RUBXD
          Length = 271

 Score = 53.5 bits (127), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 49/209 (23%), Positives = 91/209 (43%), Gaps = 16/209 (7%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +RI+Q++D H+ +     L      E+       +RP     DL+   GDL  +     +
Sbjct: 1   MRIVQMSDIHVGS----GLFRPELLEAAVRETNELRP-----DLVAVAGDLTMEGYRWEF 51

Query: 75  QHFAEGIASFRAP-CVWLPGNHDFQPAMYSALQDAGISPAKRVFI----GEQWQILLLDS 129
           +     +     P  V + GNHD +   Y   +D   S A+ + +    GE  +++ +DS
Sbjct: 52  EEARRHLDRLECPHVVVVMGNHDAKSVGYRHFEDIFGSRARSLVVPSPQGEA-KVVAIDS 110

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
               +  GE+      W++ +         +L++HHH L    +  D + LR+AG++  +
Sbjct: 111 TKPDLDEGEVGREYYAWIDSEFRGWERGPKILMIHHHILAVPGTGRDVNILRDAGDVMAM 170

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLL 218
           L +   V  +L GH H       +G R++
Sbjct: 171 LREL-KVDMVLSGHRHVPYVWSISGVRVI 198


>UniRef50_Q46D43 3,5-cyclic-nucleotide phosphodiesterase n=8 Tax=Archaea
           RepID=Q46D43_METBF
          Length = 230

 Score = 53.1 bits (126), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 57/209 (27%), Positives = 94/209 (44%), Gaps = 16/209 (7%)

Query: 40  ESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPC---VWLPGNHD 96
           E   ++LE I  ++   D+IV TGDL ++  +A Y    + I   R  C   V +PGNHD
Sbjct: 3   EIANSMLENI--NRSSPDIIVITGDLTENGLAAEYNGAKKFID--RIECKNKVIVPGNHD 58

Query: 97  FQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPE 156
            + A Y   +D   + +     GE   ++ LDS    +  G +      W+E     +  
Sbjct: 59  SRNAGYLFFEDLFKTRSTSGQFGEI-TVVGLDSSQPELDEGHIGRENYNWIENTF--SVN 115

Query: 157 RHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRR 216
              +  LHHH +P   +    + L +AG++  +L +   V  +LCGH H       N   
Sbjct: 116 GFKVFALHHHLIPIPRTGRGNNVLVDAGDVLELLDR-SGVNLVLCGHWHIPWVWRLNDML 174

Query: 217 LLATPSTC---VQFK-PHCSNFTLDTIAP 241
           +++  + C   V+ K   C NF ++  AP
Sbjct: 175 VISAGTVCSSKVRGKMSQCYNF-IEVDAP 202


>UniRef50_B9K806 Metallophosphoesterase n=1 Tax=Thermotoga neapolitana DSM 4359
           RepID=B9K806_THENN
          Length = 355

 Score = 52.0 bits (123), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 44/171 (25%), Positives = 72/171 (42%), Gaps = 23/171 (13%)

Query: 60  VATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDF--QPAMYSALQDAGISPAKRVF 117
           + TGD+  D S   +  + + +  F+ P + +PGNHD    P  Y  +      P    F
Sbjct: 82  INTGDMVFDGSVFKWGLYLKQLKRFKVPVLHVPGNHDLADDPGNYLKI----FGPLYYSF 137

Query: 118 -IGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPL-------P 169
            +G  + I+L ++         +  +QL WLE +L  +       +  H P+        
Sbjct: 138 HVGNSYFIVLNNAN-----EKCVDSYQLAWLEGELEKSRSYKYRFVFMHVPIYDPRVKKQ 192

Query: 170 AGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLAT 220
            G S  D   L+NA  L  +L K+  +  +  GHIH     +WNG   + T
Sbjct: 193 PGHSMKD---LKNALTLLNILKKY-DITMVFAGHIHGYFRGEWNGVPYIIT 239


>UniRef50_A1DIP8 Ser/Thr protein phosphatase family protein n=1 Tax=Neosartorya
           fischeri NRRL 181 RepID=A1DIP8_NEOFI
          Length = 244

 Score = 52.0 bits (123), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 44/177 (24%), Positives = 77/177 (43%), Gaps = 16/177 (9%)

Query: 46  LEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQ--PAMYS 103
           L A + +  +FD  +A GDL  D+     Q F   +  F+ P   LPGNHD      +  
Sbjct: 3   LAAQQVNTEDFDFCIAVGDLTHDRHDYQVQAFQNTLLQFKKPVHLLPGNHDISNVATLEQ 62

Query: 104 ALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEF---QLEWLERKLADAPERHTL 160
             +D  +S     F  + ++ +LLDS        E   +   +  W E +L  A      
Sbjct: 63  FTRDYNVSDHSS-FSHQGYRFVLLDSVTLISNLTEFESYTAAEWAWFENQLEAAHHAKEE 121

Query: 161 LLLHHHPLP-------AGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDL 210
           +++ HH LP       A   W   + +R  G   +++ ++ +V ++L GH H+  ++
Sbjct: 122 IIVAHHHLPFEFTEDEADAYWTFPNRVR--GRYLSLIKQY-NVHHILVGHRHETKNI 175


>UniRef50_D2QD99 Metallophosphoesterase n=1 Tax=Spirosoma linguale DSM 74
           RepID=D2QD99_9SPHI
          Length = 306

 Score = 52.0 bits (123), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 63/277 (22%), Positives = 115/277 (41%), Gaps = 50/277 (18%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDL-------AQ 67
           +R+  +TD H+     + ++G    + ++  L  ++    + DLI+  GD         +
Sbjct: 36  LRVAHLTDVHM-----QPIIGAA--KGFEKCLHHVQSLPDKPDLIINGGDAVMEAHGRGK 88

Query: 68  DQSSAAYQHFAEGIASFRA-PCVWLPGNHD----------FQPAMYSALQDAGISPAKRV 116
           D  S  ++ + + + S  A P +   GNHD          F+     A+ +     AKR 
Sbjct: 89  DSVSRQWRLYQDVLRSENALPVISCVGNHDIWCKQETKICFEAGRQWAMDE--FQMAKRF 146

Query: 117 FIGEQ--WQILLLDS---QVFGVPH-GELSEFQLEWLERKLADAPERHTLLLLHHHPLPA 170
           +  ++  W+I++LDS   +  G  +   L + Q  WLE +L   P    +L++ H P+ A
Sbjct: 147 YSIDRNGWRIIMLDSVQPKADGSWYTAHLDDEQYHWLEAELKSTPNTTPILVVSHIPILA 206

Query: 171 GCSWLDQHSLRNAG-------------ELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRL 217
            C + D     +                L  +    P+VK  L GHIH    +D+NG   
Sbjct: 207 ACVFFDGPRFSDENWSVPARWMHSDTVRLTNLFHNHPNVKAALSGHIHLTDRVDYNGVSY 266

Query: 218 LATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTL 254
               +    +     + T    A G+  ++L+ DGT+
Sbjct: 267 YCNGAVSGAWWFGKYHHT----AAGYALVDLYDDGTV 299


>UniRef50_C7PKP5 Metallophosphoesterase n=1 Tax=Chitinophaga pinensis DSM 2588
           RepID=C7PKP5_CHIPD
          Length = 303

 Score = 51.6 bits (122), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 65/284 (22%), Positives = 114/284 (40%), Gaps = 60/284 (21%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +R+  ITD HL+ +           + ++  L  I+  Q + D+I+  GD+  D +    
Sbjct: 34  LRVAHITDVHLYDKAGAP-------DFFRKCLHHIQSQQPKVDMILNGGDIVFDMNK--- 83

Query: 75  QHFAEGIASFRA---------------PCVWLPGNHDF-------QPAMYS---ALQDAG 109
               E +++                  P  +  GNHD          A+Y    +L    
Sbjct: 84  ----ENLSTIDVQWKLLHTIMKEECSLPVHYALGNHDIWWSENNKGQAVYGKQYSLDQLQ 139

Query: 110 ISPAKRVFIGEQWQILLLDSQVFGVPH----GELSEFQLEWLERKLADAPERHTLLLLHH 165
           ++     F    W+ ++LDS    V      G+L E Q+ WL  +L     +  + +L H
Sbjct: 140 LNSPYYSFTKGGWKFIVLDSVHLDVDDTWYIGKLGEAQMIWLSDELKATDAQTPVCVLSH 199

Query: 166 HPLPAGCSWLDQHSLRNAGEL-------DT-----VLAKFPHVKYLLCGHIHQELDLDWN 213
            P+    + + Q ++ N  E+       DT     +  ++P+VK  L GHIH +  + +N
Sbjct: 200 IPILTA-TLMVQDNIVNRWEMLGGDMHTDTADIIRLFYQYPNVKLCLSGHIHLKDKVVYN 258

Query: 214 GRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTE 257
               L   +    +    +  T    APG+  LEL ADG+ T +
Sbjct: 259 NVAYLCDGAVSGAWWKGNNRET----APGYGLLELFADGSFTEK 298


>UniRef50_UPI000185BF3C putative secreted protein n=1 Tax=Corynebacterium amycolatum SK46
           RepID=UPI000185BF3C
          Length = 485

 Score = 51.2 bits (121), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 69/295 (23%), Positives = 111/295 (37%), Gaps = 60/295 (20%)

Query: 6   TLP-LAGEARVRILQITDTHLFAQKHEAL----LGVNTWESYQ--------AVLEAIRPH 52
           TLP L+G+    I    DTH+    H+ +     G+++    Q        ++L+ ++  
Sbjct: 160 TLPTLSGKLLATIALTNDTHIGKPNHDGIRFGNFGLSSEPGEQPFPSMQLESLLKTVK-- 217

Query: 53  QHEFDLIVATGDLAQDQSSAAYQHFAEGIASF-RAPCVWL--PGNHDFQPAMYSALQD-- 107
           +   D IV  GD         Y  F   +  F      W    GNHD  P     +    
Sbjct: 218 EDGIDTIVVNGDCTDSNRPEEYDEFLRVMNQFGEMGKQWFVTRGNHDIHPPGLPNINGRR 277

Query: 108 -----AGISPAKRVFIG------EQW-------QILLLDSQVFGVPHGELSEFQLEWLER 149
                 G +     F G      + W       +++ LD+  FG   G ++E Q+  +  
Sbjct: 278 GRDIRKGKTYIPDYFSGLLVPTQQHWVTQVGEVRLIGLDTAEFGYAGGRINERQMRAVRA 337

Query: 150 KLADAPERHTLLLLHHHPLP--------AGCSWLDQHSLRNAGELDTVLAKFPHVKYLLC 201
           +LA  PER T+L   HHP+          G S++ + +   A  L  +LA  P  K +  
Sbjct: 338 ELAQDPERPTILFA-HHPITDDAVQSHLGGPSFMLERT--QAAALQKILAATPGAKAVFA 394

Query: 202 GHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTT 256
           GH H+        RR +A     V     C   +      G+  + +H DG+  T
Sbjct: 395 GHTHRN-------RRGVAD----VGATDFCERGSSLGYPGGYTRIHIHTDGSQVT 438


>UniRef50_O30241 LacZ expression regulatory protein (Icc) n=1 Tax=Archaeoglobus
           fulgidus RepID=O30241_ARCFU
          Length = 372

 Score = 50.4 bits (119), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 49/192 (25%), Positives = 89/192 (46%), Gaps = 16/192 (8%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRP-HQHEFDLIVATGDLAQDQSSAA 73
           +RI+ I+D H      E L+        + V +A+R  ++ E DL+V TGDL+     + 
Sbjct: 1   MRIVHISDLHF----GEELI-------REKVEKAVRQINEIEPDLLVITGDLSCWGIHSE 49

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFG 133
            +   E +   +   + +PGNHD +   Y   Q       K+ +  +   ++  DS    
Sbjct: 50  MRDAYETLLDLKPDYIAVPGNHDARNIGYEFFQ-LYFGETKKYWKNDVVSLIAADSTQPD 108

Query: 134 VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKF 193
           +  G + + Q +W+  K+    +R  +L LHHH  P   +  +++ L +AGE+  +L   
Sbjct: 109 LDDGYIGKEQRDWIVSKIR--KDRFNILALHHHIAPIPKTGRERNVLIDAGEMVELLIA- 165

Query: 194 PHVKYLLCGHIH 205
             +  +L GH H
Sbjct: 166 NGISAVLAGHRH 177


>UniRef50_D1N465 Metallophosphoesterase n=1 Tax=Victivallis vadensis ATCC BAA-548
           RepID=D1N465_9BACT
          Length = 608

 Score = 50.1 bits (118), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 51/199 (25%), Positives = 89/199 (44%), Gaps = 18/199 (9%)

Query: 43  QAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMY 102
           QA+ E    ++ + D ++ TGDL+   ++A      E +     P   LPGNH+   +  
Sbjct: 44  QAIAEI---NESDVDQVIVTGDLSNRGATAELTRVKELLDQLNKPYRALPGNHETNWSDS 100

Query: 103 SALQDAGISPAKRVFIGEQWQILLLDSQV---FGVPHGELSEFQLEWLERKLAD-APERH 158
            AL  A +  ++R F  E+  +LL+         +  G +    + +L+  LA+ A ++ 
Sbjct: 101 GALAFAELFRSER-FAFERNGVLLIGFSTGPYLKMGDGHVRAEDIAFLKDTLAERAADQK 159

Query: 159 TLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNG-RRL 217
            +++  H+PL           L N  E+  VLA + HV  L+CGH H +   +  G   +
Sbjct: 160 PVIVFCHYPL--------ADELSNGVEVAEVLAPY-HVLGLVCGHTHVQFRRNIYGIDNI 210

Query: 218 LATPSTCVQFKPHCSNFTL 236
           +  P T    K    NF +
Sbjct: 211 VCRPLTSNDGKTFGYNFIV 229


>UniRef50_A6E4I6 Putative uncharacterized protein n=1 Tax=Roseovarius sp. TM1035
           RepID=A6E4I6_9RHOB
          Length = 170

 Score = 50.1 bits (118), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 31/109 (28%), Positives = 53/109 (48%), Gaps = 3/109 (2%)

Query: 122 WQILLLDSQVFGVP---HGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQH 178
           ++++ LD+     P    G L   +L+WL+++L +A  R  ++  HH P+  G + +D  
Sbjct: 15  YRLICLDTLDEAAPDLHSGWLCPARLDWLDQRLNEAGPRPVIVFTHHPPIDTGFAGMDAI 74

Query: 179 SLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQF 227
            LRN  EL   L+   +V  ++ GHIH+ +     G       S C Q 
Sbjct: 75  GLRNRDELIARLSAADNVVQIMSGHIHRTVQGSAGGIPTAILKSPCHQM 123


>UniRef50_Q1AVF9 Metallophosphoesterase n=1 Tax=Rubrobacter xylanophilus DSM 9941
           RepID=Q1AVF9_RUBXD
          Length = 274

 Score = 50.1 bits (118), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 40/156 (25%), Positives = 72/156 (46%), Gaps = 19/156 (12%)

Query: 59  IVATGDLAQDQSSAAYQHFAEGIASFRAP-CVWLPGNHDFQPAMYSALQDAGISPAKRVF 117
           +V +GDL        Y+  AE I  FR    + +PGNHD +   Y   +        R+F
Sbjct: 42  VVVSGDLTNAGYRQEYEQAAEYIRRFRCEHLMVIPGNHDSRNVGYVHFE--------RLF 93

Query: 118 IGEQWQIL-LLDSQVFGVPH-------GELSEFQLEWLERKLADAPERHTLLLLHHHPLP 169
            GE++ ++   D+ + GV         G +      ++    A A E+  + ++HHH +P
Sbjct: 94  -GERYSVIDFEDAIMVGVDSSEPDLNDGRVGREHYGFIHESFAGAEEKLKIFVVHHHLIP 152

Query: 170 AGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIH 205
              +  +++ + +AG++  +LA    V  +L GH H
Sbjct: 153 IPGTGRERNIVFDAGDVLELLAD-TEVDLVLSGHKH 187


>UniRef50_Q9YDE7 Putative uncharacterized protein n=1 Tax=Aeropyrum pernix
           RepID=Q9YDE7_AERPE
          Length = 724

 Score = 50.1 bits (118), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 55/215 (25%), Positives = 100/215 (46%), Gaps = 28/215 (13%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQ-DQSSAAYQ 75
           I+ +TD H F    + +L    +    A++  ++ ++   DL+V TGD++    + ++Y+
Sbjct: 169 IMHLTDIH-FGAIDKGILNDVKFARDVALVNTLK-YELGLDLVVVTGDISDIGINVSSYR 226

Query: 76  HFAEGIASFRAPCVWLPGNHDFQ--PAMYSALQD-AGISPAKRVFIGEQWQILL---LDS 129
           ++A  +     P + +PGNHD+   P + S L D  G       +   +W   L   LDS
Sbjct: 227 NWAFAMNQLLVPTMTVPGNHDWAQVPGLESFLLDFYGKYNVPARYWAAKWGNFLFIGLDS 286

Query: 130 QVFGVPHGELSEFQLEWLERKLAD-APERHTLLLLHHHPLPA--GCSWLDQHSLRNA--G 184
           Q      G +    L++LE  L+  + E    ++L HHP+ +  G    D  S R A  G
Sbjct: 287 Q----SEGYVEPEGLDFLENVLSQYSGEDVVAIILVHHPIFSDPGRYKGDPESFRGALYG 342

Query: 185 ELDT----------VLAKFPHVKYLLCGHIHQELD 209
             ++          ++ ++  VK +  GHIH++ D
Sbjct: 343 SWESKFELVERFFDIINRYDMVKVVFSGHIHRDAD 377


>UniRef50_C2FYP3 Metallophosphoesterase n=1 Tax=Sphingobacterium spiritivorum ATCC
           33300 RepID=C2FYP3_9SPHI
          Length = 317

 Score = 49.7 bits (117), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 63/286 (22%), Positives = 112/286 (39%), Gaps = 65/286 (22%)

Query: 15  VRILQITDTHLFAQKH--EALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS- 71
           +RI  +TD H+  +    +A+ G+ T          ++  + + D I+ TGD   D ++ 
Sbjct: 42  LRIAHLTDIHILDKPEVSKAVAGIYT---------QLQSMKDKPDFIINTGDSLMDMNNQ 92

Query: 72  ---------AAYQHFAEGIASFRAPCVWLPGNHD--FQPAMYSALQDA------------ 108
                     A+ H A   +     C+   GNHD  + P  ++A + +            
Sbjct: 93  TKERIDTLWKAWDHAAATHSFAVKSCL---GNHDVWYLPKEHAAYEQSSKDPLYGKKWAM 149

Query: 109 ---GISPAKRVFIGEQWQILLLDSQVFGVPHG--ELSEFQLEWLERKLADAPERHTLLLL 163
              G+  A   F  + W+ + LDS  +    G     + QL+WL  +LA    +  ++L 
Sbjct: 150 TKLGLPQAYYSFEQKGWKFIALDSINYNSEKGGYTFGQEQLDWLTEELAQTSGKTPVVLF 209

Query: 164 HHHP----------------LPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQE 207
            H P                L  G    DQH   +   + ++L + P+V+  L GH+H  
Sbjct: 210 SHVPIISVTPLLYAAQRTPILKMGFPGGDQHV--DVMAVKSILKQHPNVRVALSGHVHYV 267

Query: 208 LDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGT 253
             + + G       +    +     N  LD  AP +  L+L+ DG+
Sbjct: 268 DHVAYLGVNYYCGGAVSGNW----WNGVLDDFAPAYSILDLYEDGS 309


>UniRef50_C7D3F7 Predicted protein n=5 Tax=Enterococcus RepID=C7D3F7_ENTFA
          Length = 272

 Score = 48.9 bits (115), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 32/123 (26%), Positives = 55/123 (44%), Gaps = 4/123 (3%)

Query: 55  EFDLIVATGDLAQDQSSAAYQHFAEGIASF--RAPCVWLPGNHDFQPAMYSA-LQDAGIS 111
           + DL++ +GDL +D     Y    + + +     P +   GNHD +       L   G  
Sbjct: 48  KIDLVIISGDLTEDGEPEDYAFLKQKLQTILQGIPMIVTLGNHDIKKNFRIGWLNQIGTE 107

Query: 112 -PAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPA 170
            P   V    ++ I+ LD+     P G +++ Q +WL+  L    ++  LL++HHH L  
Sbjct: 108 RPYNVVQTYPEFHIISLDNSEHDNPDGHMNKEQKDWLQTTLKKLSDKPILLVMHHHLLRE 167

Query: 171 GCS 173
             S
Sbjct: 168 QSS 170


>UniRef50_C5AJE8 Metallophosphoesterase n=1 Tax=Burkholderia glumae BGR1
           RepID=C5AJE8_BURGB
          Length = 370

 Score = 48.5 bits (114), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 31/99 (31%), Positives = 49/99 (49%), Gaps = 4/99 (4%)

Query: 57  DLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPA---MYSALQDAGISPA 113
           D     GD A + +   ++  +  +++ R P   +PG+HD++P     ++A   A + PA
Sbjct: 40  DFAFLPGDNANNGTPEQFRRISAELSALRLPIYVIPGDHDYEPGNLDAFNAFAQARL-PA 98

Query: 114 KRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLA 152
            RV  G +   L L S   G P   LS    +WLER+LA
Sbjct: 99  SRVLNGHRCIFLDLVSAGRGGPDFRLSAPDRQWLERELA 137


>UniRef50_B8MX07 Putative uncharacterized protein n=1 Tax=Aspergillus flavus
           NRRL3357 RepID=B8MX07_ASPFN
          Length = 246

 Score = 48.1 bits (113), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 43/174 (24%), Positives = 69/174 (39%), Gaps = 10/174 (5%)

Query: 46  LEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQ--PAMYS 103
           L A + +  EFD  +A GDL   + S     F +   +F  P   LPGNHD      +  
Sbjct: 3   LAAQQVNAEEFDFCIAVGDLTNSRHSYEITAFQQTYPNFTVPVHLLPGNHDVHDLSTLKQ 62

Query: 104 ALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSE---FQLEWLERKLADAPERHTL 160
             QD   S     F    ++ +LL+S        E      ++  W E +L  A      
Sbjct: 63  FTQDFNTSDHSS-FTHNGYRFILLNSITMITDLAEFKNHTAYEWSWFEHELKTAARAGER 121

Query: 161 LLLHHHPLPAGCSWLDQHSL----RNAGELDTVLAKFPHVKYLLCGHIHQELDL 210
           +++ HH LP   S  +  S     +        L +   V+++L GH H+  ++
Sbjct: 122 IIVAHHHLPFEGSEDEPDSYWTFPKRVRRKYIELIRRYGVRHILVGHRHETKNI 175


>UniRef50_D0MIH6 Metallophosphoesterase n=1 Tax=Rhodothermus marinus DSM 4252
           RepID=D0MIH6_RHOM4
          Length = 273

 Score = 48.1 bits (113), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 43/162 (26%), Positives = 69/162 (42%), Gaps = 17/162 (10%)

Query: 57  DLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQP------------AMYSA 104
           DL+V +GDL Q      ++     + +  AP + +PGNHD  P            A Y  
Sbjct: 33  DLVVVSGDLTQRARPRQFRAARAFLEALPAPTLVVPGNHDVYPWWRPLSRLVRPLARYRR 92

Query: 105 LQDAGISPAKRVFIGEQWQILLLDS-QVFGVPHGELSEFQLEWLERKLADAPERHTLLLL 163
                + PA   F+ +   +L L++     V  G LS   L +L+   A  P     +L+
Sbjct: 93  YLTDDLRPA---FVHDAVAVLGLNTAHGATVKGGRLSAEDLAYLQTFFATVPPSAVRVLV 149

Query: 164 HHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIH 205
            HH L    +       R A     V+A+   ++++LCGH+H
Sbjct: 150 IHHHLVQLQAVGPHDVARGARRALEVIAR-AGIEFILCGHLH 190


>UniRef50_C8S8V3 Metallophosphoesterase n=1 Tax=Ferroglobus placidus DSM 10642
           RepID=C8S8V3_FERPL
          Length = 373

 Score = 47.8 bits (112), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 46/191 (24%), Positives = 85/191 (44%), Gaps = 14/191 (7%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++I+ I+D H      E L+     ++ + + E I P     DL+V TGDL+     +  
Sbjct: 1   MKIVHISDLHF----GEELVRSKVEKAIKQINE-IEP-----DLVVVTGDLSCWGIHSEL 50

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
           +   E +   ++    +PGNHD +       +       K+++   +  I+ +DS    +
Sbjct: 51  REAYEALEKLKSDYFVVPGNHDARNNGIEFFE-LYFGERKKIYKDSEVVIIGVDSTQPDI 109

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
             G +   Q  W+E       +R  +L LHHH +P   +  +++ L +AGE+  +L    
Sbjct: 110 DDGYIGFEQRRWIEENFR--KDRINVLALHHHIVPIPDTGRERNVLIDAGEVVEMLINLG 167

Query: 195 HVKYLLCGHIH 205
               +L GH H
Sbjct: 168 FA-LVLAGHRH 177


>UniRef50_Q255X1 Phosphohydrolase n=13 Tax=Chlamydiaceae RepID=Q255X1_CHLFF
          Length = 293

 Score = 47.8 bits (112), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 44/165 (26%), Positives = 67/165 (40%), Gaps = 18/165 (10%)

Query: 57  DLIVATGDLAQDQSSAAY---QHFAEGIASFRAPCVWLPGNHDF-------QPAMYSALQ 106
           D I  TGD +     A +   Q F   ++   A    LPGNHD        Q   Y    
Sbjct: 66  DSICITGDFSLTALDAEFLLAQDFVNNLSQ-NASVYALPGNHDVYTQKALNQQTFYQYFP 124

Query: 107 DAGISPAKRVF--IGEQWQILLLDSQVFG---VPHGELSEFQLEWLERKLADAPERHTLL 161
           +  +   +  F  + + W ++LLD          +G +   Q   LE  +   P +  ++
Sbjct: 125 NVQLQNERISFNKLMDHWWLVLLDCSCLNGWFSANGMIQSSQTSVLENFILSLPPKENII 184

Query: 162 LLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQ 206
           + +H+PL         H L N   L  VL K+P+V+  L GH HQ
Sbjct: 185 IANHYPLLPTKD--PSHDLINHLLLQHVLKKYPNVRLYLHGHNHQ 227


>UniRef50_Q28TG5 Metallophosphoesterase n=1 Tax=Jannaschia sp. CCS1
           RepID=Q28TG5_JANSC
          Length = 659

 Score = 47.8 bits (112), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 49/196 (25%), Positives = 81/196 (41%), Gaps = 42/196 (21%)

Query: 43  QAVLEAIRPHQ-HEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAM 101
             VL++I  H     + ++  GD+  D  S     F    +    P  ++ GNHDF    
Sbjct: 179 DGVLDSILDHDLSNTECVIMLGDVMGDDLSL-LPRFMNVWSVLDLPQYYIHGNHDFD--- 234

Query: 102 YSALQDAGISPAKRVFIGEQW--------QILLLDSQVF--------------------G 133
           + A  DA  + + R   G  +          + LD+ V+                     
Sbjct: 235 FDATSDAHSADSWRQIYGPAYYSFDIGNVTFIALDNVVYPCGPEDVGPGGRDACGDDTRA 294

Query: 134 VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLR----NAGELDTV 189
           V +G + E Q++WLE  LA+ PE   ++++HH P     S++D ++ R    N  E+  +
Sbjct: 295 VYNGRVVERQMQWLEATLAEIPEDRLIVMMHHIPF---VSFVDSNAGRHQTDNLAEIHAL 351

Query: 190 LAKFPHVKYLLCGHIH 205
           LA  P V +   GH H
Sbjct: 352 LAGRPAVSF--SGHTH 365


>UniRef50_A3WFW5 Putative uncharacterized protein n=1 Tax=Erythrobacter sp. NAP1
           RepID=A3WFW5_9SPHN
          Length = 248

 Score = 47.4 bits (111), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 65/268 (24%), Positives = 100/268 (37%), Gaps = 40/268 (14%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
            R+  ++D H          GV   E+ + V +AIR  +   D +V TGD+ Q    + Y
Sbjct: 3   TRLFHVSDVHF---------GVENREALEHVAKAIRDERP--DALVCTGDVTQRAKHSEY 51

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVF-----IGEQWQ-----I 124
              AE  A    P V  PGNHD     Y  L +    P +R       +G +++     +
Sbjct: 52  AAAAEWFAGLGVPVVLEPGNHDMP---YYNLLERFSDPYRRFRRLDSEVGSRFENDDVVL 108

Query: 125 LLLDSQVFGVPH-----GELSEFQLEWL---ERKLADAPERHTLLLLHHHPLPAGCSWLD 176
           + L S V   P      G +++  LE      RKL+  P RH ++  HH   P      D
Sbjct: 109 VSLKSTVRAQPRFPWSDGIVTKRSLERTLAELRKLSGDP-RHVIVTAHH---PLLGPKED 164

Query: 177 QHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTL 236
             +    G+             ++ GH+H+  D      R +A  S  +      S    
Sbjct: 165 AGNPTIGGDRAFAALASAGADAIMTGHVHRPFDET----REMAGASMRMIGAGTLSTRLR 220

Query: 237 DTIAPGWRTLELHADGTLTTEVHRLADT 264
               P +R L       +  E+  LA T
Sbjct: 221 HGAPPSYRVLNCRRGEEMQVELRELAAT 248


>UniRef50_Q3Y3L7 Metallophosphoesterase n=1 Tax=Enterococcus faecium DO
           RepID=Q3Y3L7_ENTFC
          Length = 267

 Score = 47.4 bits (111), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 51/211 (24%), Positives = 87/211 (41%), Gaps = 11/211 (5%)

Query: 56  FDLIVATGDLAQDQSSAAYQHFAEGIASF--RAPCVWLPGNHDFQPAMYSALQDAGISPA 113
           +D I+ TGDL  +   + YQ   + +  +    P  +  GNHD +   +  +        
Sbjct: 47  YDFILLTGDLVHEGGISDYQVLRKMLDQYFPTTPYYFCRGNHDRRSVFFEGMSVESNETG 106

Query: 114 KRVFIGEQ--WQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAG 171
           + +    Q   +I+ LDS       G++S  Q+  L+  L    E+ T+LL+ HHPL   
Sbjct: 107 EYIHCTNQNGLRIISLDSAQDTQHEGKISIGQMIQLQEWLGTPAEKGTILLV-HHPL--- 162

Query: 172 CSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHC 231
            SW D   +    E    L     +  +  GHIHQ    ++  ++     S       + 
Sbjct: 163 -SWEDPSIVTEVPEGFAELIAESDILGIFVGHIHQGSSAEFADKKQFMAESLSFGVDEY- 220

Query: 232 SNFTLDTIAPGWRTLELHADGTLTTEVHRLA 262
            +++L T   G+ +  L  DG + T  H L 
Sbjct: 221 PDYSLFTNRTGFTSGSL-IDGKIFTYQHYLT 250


>UniRef50_Q1NCC3 Putative uncharacterized protein n=1 Tax=Sphingomonas sp. SKA58
           RepID=Q1NCC3_9SPHN
          Length = 296

 Score = 47.4 bits (111), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 44/168 (26%), Positives = 69/168 (41%), Gaps = 29/168 (17%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           RI  ++D H  A     +     W      LE  RP     DL+V +GD  Q      ++
Sbjct: 3   RIAHLSDIHFGANDPRIVDAATAW------LEERRP-----DLVVISGDFTQRARVGQFR 51

Query: 76  HFAEGIASFRA---PCVWLPGNHDFQPAMYSALQDAGISPAKRV--FIGEQWQILLLDSQ 130
             A  +   RA     + +PGNHD    +Y  L+   ++P +R   +I         D +
Sbjct: 52  QAAAWLGKLRAAGLKTLVIPGNHDV--PLYDVLRRF-LTPLRRYRRYISHDLCPFYEDDE 108

Query: 131 V--FG--------VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPL 168
           V  FG        +  G ++  Q++ L  + A  P   T +L+ HHPL
Sbjct: 109 VAIFGINTARSLTIKDGRINHDQMDMLRHRFAHVPRDKTRILVTHHPL 156


>UniRef50_Q2SWK2 Ser/Thr protein phosphatase family protein n=37
           Tax=Burkholderiaceae RepID=Q2SWK2_BURTA
          Length = 306

 Score = 47.0 bits (110), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 50/174 (28%), Positives = 73/174 (41%), Gaps = 23/174 (13%)

Query: 46  LEAIRPHQHEFDLIVATGDLAQDQSSAA-----YQHFAEGIASFRA-PCVWLPGNHDFQP 99
           +EA+       D ++ TGDL       A      + F   +A  RA P   +PG HD   
Sbjct: 71  IEAVNALPVAPDFVMFTGDLTHTTDDPAERRTRMRQFQSIVAQLRAKPLHLMPGEHD--- 127

Query: 100 AMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV------PHGELSEFQLEWLERKLAD 153
               A  DAG   A R   G+           F V      P G + + Q+EWL + LA 
Sbjct: 128 ----ASLDAGA--AYREIFGDTHYAFDHKGVHFVVVDNVSDPAGRVGDAQIEWLAQDLAR 181

Query: 154 APERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQE 207
            P+   +++  H PL       D  + R+  ++  VL  +P+V  +  GHIHQE
Sbjct: 182 QPKDARIVVFTHRPLFDLAPQWDW-ATRDGAKVVDVLMPYPNVT-VFYGHIHQE 233


>UniRef50_Q03AS7 Predicted phosphohydrolase n=9 Tax=Lactobacillus RepID=Q03AS7_LACC3
          Length = 442

 Score = 47.0 bits (110), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 60/239 (25%), Positives = 101/239 (42%), Gaps = 54/239 (22%)

Query: 59  IVATGDLAQDQSSAAYQHFAEGIASFRAPCV-------WLPGNHDFQPAMYSALQDA--- 108
           +V TGD+  +   A+    AE I     P V        +PGNHD       A +     
Sbjct: 93  LVITGDVTFNGEKAS----AESIMRRLQPLVANGTKVLIIPGNHDIYDGWARAYKGKRQL 148

Query: 109 ---GISPAK----------------------RVFIGEQWQILLLDSQVFGV------PH- 136
               ISP+                       RV +   +Q+L+LDS ++ +      P+ 
Sbjct: 149 LTEQISPSDWRNIFHTSYEQAVAQDPNSLSYRVNLNRNYQLLMLDSNIYTIEPSNRPPNT 208

Query: 137 -GELSEFQLEWLERKLADAPERH-TLLLLHHHPLPAGCSWLDQ-HSLRNAGELDTVLAKF 193
            G+L+   ++W+ ++LA   + H   ++  HH L A    ++Q   L N+ +L  +L  +
Sbjct: 209 GGKLTPQTMKWVRQQLAAGQKAHRKSIVFMHHNLYAHNEAVNQGFVLDNSDQLKPLLKAY 268

Query: 194 PHVKYLLCGHIH-QELDLDWNGR-RLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHA 250
            HV  L  GHIH Q++  D +G+   +   S      P  +++ + T AP   T + HA
Sbjct: 269 -HVLLLFSGHIHAQDISRDPDGQCPTIEVVSGAFSISP--ASYGVVTFAPNRITYQKHA 324


>UniRef50_C1VB71 Predicted phosphohydrolase n=1 Tax=Halogeometricum borinquense DSM
           11551 RepID=C1VB71_9EURY
          Length = 344

 Score = 46.6 bits (109), Expect = 8e-04,   Method: Compositional matrix adjust.
 Identities = 62/236 (26%), Positives = 95/236 (40%), Gaps = 36/236 (15%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESY-------QAVLEAIRPHQHEFDLIVATGDLA 66
           R RI  ++D HL            TW+ Y       +A + AI  +    D  ++ GDL 
Sbjct: 35  RTRIAVVSDPHLTPTA------TGTWKVYHRTETRLRAAIAAI--NDLNVDATLSLGDLT 86

Query: 67  QDQSSAAYQHFAEGIASFRAPCVWLPGNHDF--QPAMYSA--LQDAGISPAKRVF----- 117
           +D     +    E +A    P V +PGNHD   Q   Y A  + + G   A+  F     
Sbjct: 87  RDGHPEEFDCVDELLADLDTPFVSVPGNHDVPKQWDDYEAPTVDEFGARYARGAFPFHVS 146

Query: 118 IGEQWQILL----LDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHH---HPLPA 170
           +G    I L     D  ++    G +    + WL+  L++      ++  HH   HP   
Sbjct: 147 VGGVDLIGLDTASGDGTLYDSHEGLVPSEHVAWLDETLSEV--ESPIVASHHNVFHPREH 204

Query: 171 GCSWLDQ--HSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTC 224
              + D+  + LRNA E+  VL+       +L GHIH        G R +  P+TC
Sbjct: 205 TGQFADEDFYQLRNADEVVEVLSSGGD-PLVLSGHIHWPATARRGGVREIIAPATC 259


>UniRef50_B2TAN8 Metallophosphoesterase n=1 Tax=Burkholderia phytofirmans PsJN
           RepID=B2TAN8_BURPP
          Length = 366

 Score = 46.6 bits (109), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 51/201 (25%), Positives = 84/201 (41%), Gaps = 23/201 (11%)

Query: 55  EFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQP----AMYSALQDAGI 110
           + D  V  GD A D + A Y      +     P   +PG+HDF+     A ++ L+   +
Sbjct: 33  QIDFAVLPGDNADDGTPAQYDILRAELDDLEIPVHIIPGDHDFKSRNLDAFHTVLRAEHL 92

Query: 111 SPAKRVFIGEQWQILLLD--SQVFGVPHGELSEFQLEWLERKL--ADAPERHTLLLLHHH 166
             A  V     ++   LD  S   G P   L + Q++WL+ +L  A A  + T++  H +
Sbjct: 93  PKATPV---RDYRCFFLDYVSAGTGGPDFRLGQSQMDWLKAELQNAAAAGKETVVFAHGY 149

Query: 167 PLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQ 226
           P        D      A     +L +F  V  +  GH H   +L  +GR + A+  +  Q
Sbjct: 150 P-------ADLADANEAVAFHRLLREF-RVAVVDMGHTHYN-ELANDGRTIYASTRSTGQ 200

Query: 227 FKPHCSNFTLDTIAPG---WR 244
            +   + F+L  +  G   WR
Sbjct: 201 IEEGPAGFSLLAVDSGVVSWR 221


>UniRef50_A6WZI2 Metallophosphoesterase n=49 Tax=Proteobacteria RepID=A6WZI2_OCHA4
          Length = 281

 Score = 46.6 bits (109), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 50/165 (30%), Positives = 72/165 (43%), Gaps = 21/165 (12%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS--A 72
           +RI+QITDTHL   K         WE   A ++  +P     DL++ TGDL  D +   A
Sbjct: 1   MRIVQITDTHLSPIKPHF---NRNWEPLVAWIDQQKP-----DLVIHTGDLTVDGADVEA 52

Query: 73  AYQHFAEGIASFRAPCVWLPGNHDF-------QPAMYSALQ--DAGISPAKRVFIGEQWQ 123
                   +    A  + LPGNHD        QP     L      I P +       W+
Sbjct: 53  DLLFCRTCLNELPARVLSLPGNHDIGHLPESHQPVNPQRLMRWRRHIGPDRWAENFGNWR 112

Query: 124 ILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPL 168
           I+ L+S V G    E +E Q +WLE +L ++ +   + +  H PL
Sbjct: 113 IIGLNSLVIGSGEAEEAE-QFQWLEDELKNS-DGKPVAVFAHKPL 155


>UniRef50_C5PKR3 Putative uncharacterized protein n=2 Tax=Sphingobacterium
           spiritivorum RepID=C5PKR3_9SPHI
          Length = 627

 Score = 46.6 bits (109), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 44/209 (21%), Positives = 82/209 (39%), Gaps = 25/209 (11%)

Query: 53  QHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISP 112
           Q + D ++ +GD+ +  + A  +   + + S + P   +PGNHD          + G + 
Sbjct: 61  QQQLDFVILSGDITEFGADAELRLAKQILDSLQLPWYVIPGNHD------GNWSENGANT 114

Query: 113 AKRVFIGEQWQILLLDSQVFGVPH--------GELSEFQLEWLERKLADAPERHT-LLLL 163
            ++VF GE +          G           G++    L W++      P+  T L+ +
Sbjct: 115 FRKVFGGETFFFRHKGYMFMGTNSGPNMRMSPGQIPRENLVWMDSVFKANPDTQTPLIYI 174

Query: 164 HHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPST 223
           +H+P           SL N  E    + K  +V+   CGH H  +  +W G   +   S 
Sbjct: 175 NHYP--------QDSSLNNWFEAINRVKK-RNVQLAFCGHGHANVKYNWEGIPGIMGRSN 225

Query: 224 CVQFKPHCSNFTLDTIAPGWRTLELHADG 252
            ++ K     + + TI  G    ++   G
Sbjct: 226 -LRAKDSIGGYNIVTIGDGKAVYQVKKPG 253


>UniRef50_B5ISV8 Ser/Thr protein phosphatase family protein n=1 Tax=Thermococcus
           barophilus MP RepID=B5ISV8_9EURY
          Length = 658

 Score = 46.6 bits (109), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 32/113 (28%), Positives = 54/113 (47%), Gaps = 11/113 (9%)

Query: 57  DLIVATGDLAQDQS-SAAYQHF---AEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISP 112
           D+I+ATGD+      S AY +     E   +   P + + GNHD  P  +S +    I+P
Sbjct: 183 DVIIATGDVVDTAGDSKAYGYLLGLMENAIAAGKPTIIVKGNHDDPPKYFSKM----IAP 238

Query: 113 AKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHH 165
                   ++ I+ LDS          +  QLEW+E+ L   P++  ++++HH
Sbjct: 239 PTYYLTIGKFIIIALDSDN---ERSHPTMEQLEWMEKILEQNPDKIPIIIVHH 288


>UniRef50_A0RA77 Purple acid phosphatase/fibronectin domain protein n=79
           Tax=Bacillus RepID=A0RA77_BACAH
          Length = 824

 Score = 46.2 bits (108), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 51/214 (23%), Positives = 85/214 (39%), Gaps = 28/214 (13%)

Query: 12  EARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
           E ++    ++D H+   K+        W+     L  + P Q   D  V  GD     S 
Sbjct: 50  EKKIVFPVVSDVHI---KNSGTDDTFRWKRAIEQLNTLAPKQ---DAFVIVGDFTDTGSL 103

Query: 72  AAYQHFAEGI---ASFRAPCVWLPGNHDF------QPAMYSALQDAGISPAKRVFIGEQW 122
             Y  F +     A+  A  +   GNHD+      + A    L+  G+       + + +
Sbjct: 104 QQYDRFMQVYNENANKDAVRMNSLGNHDYWNGLSVEGAQKRFLEKTGMESIYYHKVVKGY 163

Query: 123 QILLLDSQVFGVPHGELSEFQLEWLERKLA----DAPERHTLLLLHHH---PLPAGCSWL 175
             L++  +  G  HG  S+ Q+ WL+ ++A    D PE+   + LH H    +     W 
Sbjct: 164 HFLVMSPE-NGTTHGYYSDKQINWLKEEMAKAQKDDPEKPIFVFLHQHIKETVYGSHEWG 222

Query: 176 DQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELD 209
            Q S +    ++TVL ++P       GH H  LD
Sbjct: 223 TQDSAK----INTVLKEYPQA-ITFSGHSHYPLD 251


>UniRef50_Q7NJG1 Glr1871 protein n=1 Tax=Gloeobacter violaceus RepID=Q7NJG1_GLOVI
          Length = 318

 Score = 45.8 bits (107), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 57/238 (23%), Positives = 98/238 (41%), Gaps = 34/238 (14%)

Query: 8   PLAGEARVRILQITDTHL----------FAQKHEALLGVNTWESYQAVLEAIRPHQHEFD 57
           P+  E ++  +QI+D HL           +++ E LL +   E   A+           D
Sbjct: 18  PVKLEPQLNFVQISDVHLRPNAGRSGWWLSERPEHLLQLAV-EKVCAL--------GGVD 68

Query: 58  LIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVF 117
            +V TGDL     +AA   F     +   P   + GNHD     +          A+R+ 
Sbjct: 69  FVVFTGDLFDQAEAAALDQFVAIAGALPCPYHVVVGNHDVVGKPWPGRLTKQTF-AERLA 127

Query: 118 IGEQ----------WQILLLDSQVFGVPH--GELSEFQLEWLERKLADAPERHTLLLLHH 165
           + E+          +++++LD+     PH  G L   Q+EWL  +L    +   ++ LHH
Sbjct: 128 LPEKLYYSVPVKPGYRLIVLDTVPAPFPHAQGCLPAEQMEWLRWQLLVHRDEQVIVALHH 187

Query: 166 HPL-PAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPS 222
            P+ PA       + L +  +   ++A  P+V  +L GH+H      +  R   + PS
Sbjct: 188 PPVAPAYFRDFRLNPL-DGSQFAELMAASPNVVAVLSGHLHVPRRWSYRKRPYFSAPS 244


>UniRef50_A4WK20 Metallophosphoesterase n=5 Tax=Thermoproteaceae RepID=A4WK20_PYRAR
          Length = 641

 Score = 45.8 bits (107), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 44/165 (26%), Positives = 69/165 (41%), Gaps = 32/165 (19%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA-A 73
           +RI+Q+TD H+  +   A L       Y+ +  A+      +D++  TGDLA        
Sbjct: 110 LRIIQLTDIHVGVELDMASL-------YRLIHGALVASGGPYDVVFFTGDLADVGGQVWH 162

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV--FIGEQ--------WQ 123
           Y  F +  A+   P   +PGNHD           AG  P      F+G          + 
Sbjct: 163 YTLFTKYAATIPKPVFAIPGNHD----------HAGDDPLTNYQKFVGRPVWYRVIGPYL 212

Query: 124 ILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPL 168
           I+ LDS       G L + Q++  E  L   P++  ++L+HH P 
Sbjct: 213 IIGLDSGF----DGYLRDDQVKMYEEVLKRYPDKVKIVLIHHPPF 253


>UniRef50_UPI0001BC808F hypothetical protein BacD2_17610 n=1 Tax=Bacteroides sp. D2
           RepID=UPI0001BC808F
          Length = 520

 Score = 45.8 bits (107), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 48/221 (21%), Positives = 87/221 (39%), Gaps = 33/221 (14%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ----SSA 72
           I   TD HL   + +  L       Y  ++  I+   ++    +  GD+  D     +  
Sbjct: 115 IFMFTDIHLTNDRVDNDLPQFGKTFYPDIVSQIKARANKPVYAICLGDMTTDVKWHINHY 174

Query: 73  AYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAG----------ISPAKRVFIGEQW 122
           A   + E +  F  P     GNHD +  +   + D            I P    F    W
Sbjct: 175 ALPEYLETMKDFPIPVYHAMGNHDNERKVIENISDWDFYGESVYKDVIGPNYYSFNIGAW 234

Query: 123 QILLLDSQVFGVP---HGELS--------EFQLEWLERKLADAPERHTLLLLHHHP---- 167
            +++LD+ + G P   +G+L+        + Q+EW+++ L+  P+   +++  H P    
Sbjct: 235 HVMILDNIITGGPVKKNGKLNYQFTYRIDDQQMEWIKKDLSFMPKNTPIMVGMHVPPLKY 294

Query: 168 --LPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQ 206
             +  G    D +   NA E     A+F  V+ +  GH H+
Sbjct: 295 TGMKNGVLETD-YDFENAKEFLDCFAEFNQVQ-IFAGHTHR 333


>UniRef50_B5JMC7 Ser/Thr protein phosphatase family protein n=1 Tax=Verrucomicrobiae
           bacterium DG1235 RepID=B5JMC7_9BACT
          Length = 309

 Score = 45.4 bits (106), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 52/229 (22%), Positives = 87/229 (37%), Gaps = 45/229 (19%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQD----QS 70
           +RI  +TD H+   K          E     ++  +    + DLI+  GD   D      
Sbjct: 33  LRIAHLTDIHVMPDKDAP-------EKMARAIQHAQSQTDKPDLILNGGDCIMDALKRSK 85

Query: 71  SAAYQHFAE--GI--ASFRAPCVWLPGNHDF---------QPAMYS---ALQDAGISPAK 114
           S     ++E  G+       P     GNHD          +   Y    A+++  +    
Sbjct: 86  SETKAQWSEWHGVLKNELELPFYSAIGNHDIWGWALPNSKKNVSYGKQWAMEELALKQRY 145

Query: 115 RVFIGEQWQILLLDSQVFGVPH-----GELSEFQLEWLERKLADAPERHTLLLLHHHPLP 169
             F    WQ ++LDS  F          +L E Q  WL + LA++  +  + +L H P+ 
Sbjct: 146 YSFEKNNWQFIVLDSSHFEPSFKSGYTAKLDEAQFAWLAQTLAESDPKKPICILSHIPII 205

Query: 170 AGCSWLDQHSLR-------------NAGELDTVLAKFPHVKYLLCGHIH 205
           + C + D  + +             +A  +  + A+ P+VK  L GHIH
Sbjct: 206 SFCPFFDGDNEKSGDWQVPGPWMHIDARRIKDLFAQHPNVKLALSGHIH 254


>UniRef50_B1ZFT6 Metallophosphoesterase n=1 Tax=Methylobacterium populi BJ001
           RepID=B1ZFT6_METPB
          Length = 387

 Score = 45.4 bits (106), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 55/205 (26%), Positives = 78/205 (38%), Gaps = 25/205 (12%)

Query: 56  FDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGIS---- 111
            D +   GD A +     Y     G+   R P   + G+HD +     A   AG+     
Sbjct: 42  LDFVFLPGDNADNGRPEQYALVRAGLDGLRLPAHVITGDHDMEGGSLDAFY-AGLGVPRL 100

Query: 112 PAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKL--ADAPERHTLLLLHHHPLP 169
           P      G +   L L     G P   L   QL WLER+L  A+A  R   L +H +P  
Sbjct: 101 PYAVTVSGTRCLFLDLCGSGSGGPDFRLGSEQLSWLERELAGAEAEGRDCALFMHSYPA- 159

Query: 170 AGCSWLDQHSLRNAGELDTVLAKFPH---VKYLLCGHIHQELDLDWNGRRLLATPSTCVQ 226
                     L+  GE  T +A+  H   V+ +  GH H   +L  +GR + A   +  Q
Sbjct: 160 ---------DLKAEGE-GTRVAELVHRGPVRLVEMGHTHYN-ELANDGRTVYAACRSTGQ 208

Query: 227 FKPHCSNF---TLDTIAPGWRTLEL 248
            +     +    LD     WR  EL
Sbjct: 209 IEEGPVGYAIAALDRGGVAWRFKEL 233


>UniRef50_C6W404 Metallophosphoesterase n=1 Tax=Dyadobacter fermentans DSM 18053
           RepID=C6W404_DYAFD
          Length = 259

 Score = 45.1 bits (105), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 50/207 (24%), Positives = 82/207 (39%), Gaps = 37/207 (17%)

Query: 13  ARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA 72
           AR+  L ++DT  F    ++    +  E +  V  A R  Q +   ++  GD++    + 
Sbjct: 36  ARISQLPVSDTTRFILMGDSQRWYDECEDF--VKSANR--QKDISFVLHAGDISDFGLTQ 91

Query: 73  AYQHFAEGIASFRAPCVWLPGNHD------------FQPAMYSALQDAGISPAKRVFIGE 120
            ++   E +   + P + + GNHD            F P  Y+          K +FI  
Sbjct: 92  EFKWVNEIMTRLKYPYLTVIGNHDIIANGSSTYRRMFGPLNYTFT----FGRDKFIFIDS 147

Query: 121 QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL 180
             +    D  V  VP          WL+ +LAD PE+   +++ H P        D    
Sbjct: 148 NSREYAFDGSVPDVP----------WLKAQLADNPEKKNTIVVAHVPP------FDADFD 191

Query: 181 RNAGE-LDTVLAKFPHVKYLLCGHIHQ 206
           +N  +     LA  PHVK+ L GH H+
Sbjct: 192 KNLEKPFTQALADDPHVKFSLYGHQHR 218


>UniRef50_A1WSG8 Putative cAMP phosphodiesterase n=1 Tax=Verminephrobacter eiseniae
           EF01-2 RepID=A1WSG8_VEREI
          Length = 140

 Score = 45.1 bits (105), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 22/67 (32%), Positives = 35/67 (52%)

Query: 156 ERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGR 215
           +R T++ +HH P   G + +D   L  A  L  +L + P V+ LLCGH+H+ +   + G 
Sbjct: 19  DRPTVIAMHHPPFATGIAHMDALGLEGADALAQLLRQHPQVERLLCGHLHRSIQCRFGGT 78

Query: 216 RLLATPS 222
                PS
Sbjct: 79  LASTCPS 85


>UniRef50_C6XUF6 Metallophosphoesterase n=1 Tax=Pedobacter heparinus DSM 2366
           RepID=C6XUF6_PEDHD
          Length = 611

 Score = 45.1 bits (105), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 42/203 (20%), Positives = 82/203 (40%), Gaps = 32/203 (15%)

Query: 20  ITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAE 79
           +TDTH+     E        E  +  +  I   Q + D IV TGD+ +  +    +    
Sbjct: 27  VTDTHVGTATGE--------EDLRRTVNDIN-KQTDLDFIVVTGDVTEMGTKLELKLAKS 77

Query: 80  GIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQ--------ILLLDSQV 131
            ++  + P   +PGNHD      +   ++G     R F  +++         I       
Sbjct: 78  ILSELKKPYYVIPGNHD------TGWSESGGVDFIREFGDDKFTFDHNGYRFIACASGPY 131

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
             +  G +    + WL++ L +      ++ ++H+P+         +SL N  E    + 
Sbjct: 132 VRMSDGHIPRDAVIWLDKVLKNTSATMPVIFINHYPV--------DNSLDNWYEATDRIK 183

Query: 192 KFPHVKYLLCGHIHQELDLDWNG 214
           K+ +++Y +CGH H    L++ G
Sbjct: 184 KY-NIQYAICGHGHSNQALNFEG 205


>UniRef50_B5HU26 Integral membrane protein n=17 Tax=Streptomyces RepID=B5HU26_9ACTO
          Length = 562

 Score = 45.1 bits (105), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 26/82 (31%), Positives = 42/82 (51%), Gaps = 15/82 (18%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +R+L ++D HL            +W+   +++E     Q++ D+IV +GD   D  +AA 
Sbjct: 266 IRVLHVSDIHLNPA---------SWKIIASLVE-----QYKVDVIVDSGD-TMDHGTAAE 310

Query: 75  QHFAEGIASFRAPCVWLPGNHD 96
             F + I    AP VW+ GNHD
Sbjct: 311 NGFLDPIPDLGAPYVWVRGNHD 332


>UniRef50_C8QWM6 Metallophosphoesterase n=1 Tax=Desulfurivibrio alkaliphilus AHT2
           RepID=C8QWM6_9DELT
          Length = 397

 Score = 44.7 bits (104), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 61/216 (28%), Positives = 88/216 (40%), Gaps = 49/216 (22%)

Query: 8   PLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQ 67
           P   E  +RI++ITD HL     EA L         A +E  RP     D++VATGD+  
Sbjct: 170 PWPAERPLRIVKITDVHLGLLVQEARLA-----PMLAAVEQARP-----DILVATGDIVD 219

Query: 68  DQSSAAYQHFAEGIASFRAPC--VWLPGNHDFQPAMYSA---LQDAGIS--PAKRVFIGE 120
            Q      H A  I    AP     + GNH+F      +   L++AG +    + V IG 
Sbjct: 220 GQGD-GIAHLAAKIRRLEAPLGKFAILGNHEFYVGAEQSRAFLEEAGFTVLRGESVVIGN 278

Query: 121 QWQILLLDSQVFGVPHGELSEFQLEWLERK-LADAPERHTLLLLHHHP--LPAGCSWLDQ 177
           + +I  +D +  G+  G     Q    ER+ LA+ P     +LL H P  +P G      
Sbjct: 279 RLRIAGVDDRT-GIAMGLTPPEQ----ERELLAELPAATYNILLKHQPEIVPGG------ 327

Query: 178 HSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWN 213
                            HV   L GH+H+   + +N
Sbjct: 328 -----------------HVDLQLSGHVHRGQLVPFN 346


>UniRef50_B3EHZ5 Metallophosphoesterase n=1 Tax=Chlorobium limicola DSM 245
           RepID=B3EHZ5_CHLL2
          Length = 276

 Score = 44.7 bits (104), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 51/236 (21%), Positives = 91/236 (38%), Gaps = 31/236 (13%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +RI  ITD H F    ++ +G+ T     A +     ++   D ++  GDL +   S A+
Sbjct: 1   MRIGLITDIH-FPVDDDSGIGLRTATDILAGMAFFCSNR--VDFVLQLGDLIKGTDSRAH 57

Query: 75  QHFAEGI---ASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQV 131
           +   + +     ++     + GNH         L++ G+      F  E ++ L+LD   
Sbjct: 58  EELRQVVPMLNKYQGRIRHVIGNHCMAVPRKELLRELGLPFPYYAFTAECFRFLVLDGMD 117

Query: 132 FGVPH------------------------GELSEFQLEWLERKLADAPER-HTLLLLHHH 166
             + +                        G + E Q+EW+  +L +A      ++   H 
Sbjct: 118 VSIRNEPETGADRKLLRSCLEQPELHDYCGAIGERQMEWITSELLNAGTNGEQVIATCHF 177

Query: 167 PLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPS 222
           PL    S +    L N  E+  +L+ +P VK  + GH H       NG   L  P+
Sbjct: 178 PLHPATSDMKHGLLWNHREVRELLSAYPAVKACIGGHYHYGGYTKENGLHFLVLPA 233


>UniRef50_A9B0W4 Metallophosphoesterase n=1 Tax=Herpetosiphon aurantiacus ATCC 23779
           RepID=A9B0W4_HERA2
          Length = 288

 Score = 44.7 bits (104), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 51/181 (28%), Positives = 83/181 (45%), Gaps = 24/181 (13%)

Query: 40  ESYQAVLEA---IRPHQHEFDLIVATGDLAQDQS-SAAYQHFAEGIASFRAPCVWLPGNH 95
           E  Q +LEA   I+P      L V +GD  Q     + +    + +A    P + + GNH
Sbjct: 20  EKAQQILEAAWQIKP-----TLTVLSGDFVQRADIRSQWLTIRDFVAQLPQPTIAVMGNH 74

Query: 96  D--FQPAMYSALQ-----DAGISPAKRVFIGEQ--WQILLLDSQVFGVPHGELSEFQLEW 146
           D     A+Y  L+        ISP      G      + +  ++ F V  G+L++ QL  
Sbjct: 75  DVPLYNALYRMLRPNYYYKKYISPILEPVWGNDDFVAVGVNTTRSFTVDGGKLTDQQLLE 134

Query: 147 LERKLADAPERH-TLLLLHHHP-LPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHI 204
           LER LA  P+    ++++HHHP +P G +   +  ++NA        +  +V+ +LCGH 
Sbjct: 135 LERSLARYPDSLCKIVVMHHHPVMPPGET---RDVIQNAAAALRTFDR-SNVELVLCGHT 190

Query: 205 H 205
           H
Sbjct: 191 H 191


>UniRef50_B1ZLW2 Metallophosphoesterase n=6 Tax=Alphaproteobacteria
           RepID=B1ZLW2_METPB
          Length = 294

 Score = 44.3 bits (103), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 56/210 (26%), Positives = 81/210 (38%), Gaps = 37/210 (17%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           RI  I+D H F +   A++     ++  A L    P     DLIVA+GD         Y 
Sbjct: 3   RIAHISDLH-FGRTDTAVV-----DALAAELNRDPP-----DLIVASGDFTMRARRKEYV 51

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV--FIGEQWQILLLDSQVFG 133
                +    AP + +PGNHD     Y  L      P  R   FI    +   LD ++  
Sbjct: 52  EARAFLDGLTAPWIAVPGNHDI---AYFKLFTRFFHPFGRYRRFIARDTEPTFLDDEIAV 108

Query: 134 V--------------PHGELSEFQLEWLERKLADAPERHTLLLLHHHP-LPAGCSWLDQH 178
           V                G+++  Q+   E +LA  PE    +++ HHP +P    W  + 
Sbjct: 109 VCLNTVRTWAPETDWSQGKITRAQIARTEERLAALPEHVFRIVVGHHPFMPP--PWDAEA 166

Query: 179 SLRNAGELDTVLAKFPH--VKYLLCGHIHQ 206
            L   G  D  L  F    V   L GH+H+
Sbjct: 167 RL--VGRADEALDAFRRHGVGLTLAGHLHR 194


>UniRef50_D2QP98 Metallophosphoesterase n=1 Tax=Spirosoma linguale DSM 74
           RepID=D2QP98_9SPHI
          Length = 304

 Score = 43.9 bits (102), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 67/289 (23%), Positives = 116/289 (40%), Gaps = 47/289 (16%)

Query: 2   ESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVA 61
           E+ +   LA +  VR   + DTH+              E        ++    +   I+ 
Sbjct: 19  EAAIAPNLARKRSVRFAYLGDTHITPDAKPV-------ERIAKCFHHVQNQADKPSFILH 71

Query: 62  TGD-----LAQDQSSAAYQHFA-EGI--ASFRAPCVWLPGNHD---FQPA----MYS--- 103
            GD     LA+D+     Q  A  G+  A    P  +  GNHD   F+ A    +Y    
Sbjct: 72  GGDVIMDALAEDRQKVQQQWDAWNGLVKADNSLPIEYCIGNHDIWGFENAKNDLLYGKKW 131

Query: 104 ALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGE-----LSEFQLEWLERKLADAPERH 158
           A+    IS   R F    W  ++LDS V   P G+     +   Q++WL+  LA    + 
Sbjct: 132 AIDQMKISGRYRSFDRNGWHFIVLDS-VQPKPDGKWYTGNIDAEQMDWLKADLAKTNPKT 190

Query: 159 TLLLLHHHPLPAGCSWLDQHSLR-------------NAGELDTVLAKFPHVKYLLCGHIH 205
            +L+L H P+ +   +    +++             N  +L  +  ++P+VK  L GH+H
Sbjct: 191 PILVLSHIPIFSPTGFFSDTNVKDGNWTISAGTILANTPDLLKLFYQYPNVKAALSGHMH 250

Query: 206 QELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTL 254
               +++NG   L   +    +    S+    T A G+   +L+ DG++
Sbjct: 251 LLDRVEYNGVAYLCNGAVSGNWWK--SDVYQQTKA-GYALFDLYDDGSV 296


>UniRef50_A1S175 Metallophosphoesterase n=1 Tax=Thermofilum pendens Hrk 5
           RepID=A1S175_THEPD
          Length = 706

 Score = 43.9 bits (102), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 61/254 (24%), Positives = 108/254 (42%), Gaps = 56/254 (22%)

Query: 2   ESLLTLPLAGEARVRILQITDTHLFAQKHEALLG-VNTWESYQAVLEAIRPHQHEFDLIV 60
            S+  LP +   ++RI+ ++D H  A + + + G +N +  Y  V   + P     DL++
Sbjct: 135 RSVWVLP-STPTKLRIVHVSDQHYGAGQPDVITGDMNRFAGY-LVASLLGP-----DLVI 187

Query: 61  ATGDLA----QDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV 116
            TGD+A    +DQ + A  +    + SF  P   +PGNHD  P  +   +  G +   R+
Sbjct: 188 DTGDIADTASEDQYAQAVSYEQAFLYSF--PIFAVPGNHDHPPDNF--YKYYGDTYWYRL 243

Query: 117 FIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLD 176
            IG++  ++ L S   G P  E    QL+W  + L         ++L HHP+     +  
Sbjct: 244 -IGDKLLVVGLFSPEQGYPPME----QLQWAGQVLESNKAVPVKIVLVHHPV-----FYF 293

Query: 177 QHSLRNAGELDTVLAKF-----PH-------------------------VKYLLCGHIHQ 206
           Q  L+   +   V+A +     P+                         V Y+  GH+H+
Sbjct: 294 QGELKTRYDDQNVIAPYDPQKNPNSPVSSYWSTNMEAVRTFLRMVEDYRVNYVFSGHVHR 353

Query: 207 ELDLDWNGRRLLAT 220
           +L + +   R  +T
Sbjct: 354 DLFVKYTSTRTGST 367


>UniRef50_A6DHY4 Putative uncharacterized protein n=1 Tax=Lentisphaera araneosa
           HTCC2155 RepID=A6DHY4_9BACT
          Length = 291

 Score = 43.9 bits (102), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 49/204 (24%), Positives = 78/204 (38%), Gaps = 37/204 (18%)

Query: 35  GVNTWESYQAVLEAIRPH--QHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLP 92
           GV  + S    L     H  + + D ++  GDL  D+   ++        S +A      
Sbjct: 42  GVRKYSSSHKKLAQCVEHFNKEDLDFVIHLGDLI-DKDFKSFDVVLPIYNSLKADHYHAL 100

Query: 93  GNHDFQPA---MYSALQDAGISPAKRVFIGEQWQILLLD--------------------- 128
           GNHDF  A           G+      F    W+ ++LD                     
Sbjct: 101 GNHDFDVADELKKDVPTKMGMDSKYHYFDKANWRFIILDGNDVSFHAYPKESPEYKYAAE 160

Query: 129 ---SQVFGVP--HGELSEFQLEWLERKLADAPE-RHTLLLLHHHPLPAGCSWLDQHSLRN 182
              ++    P  +G + E Q++WLE  L ++ E    ++L  H P+       D H+L N
Sbjct: 161 YYKTKKITSPKWNGAVGEEQMKWLETLLQESQEGNQQVILFSHFPVYPK----DPHNLWN 216

Query: 183 AGELDTVLAKFPHVKYLLCGHIHQ 206
           A EL  +L  +P VK  + GH H+
Sbjct: 217 AKELVALLEDYPCVKAYINGHNHK 240


>UniRef50_D1X994 Metallophosphoesterase n=1 Tax=Streptomyces sp. ACT-1
           RepID=D1X994_9ACTO
          Length = 563

 Score = 43.9 bits (102), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 15/82 (18%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +R+L ++D HL             W    +++E     Q+E D+IV +GD   D  SA  
Sbjct: 287 IRVLHVSDIHLNPA---------AWHIIASLVE-----QYEIDVIVDSGD-TMDHGSAPE 331

Query: 75  QHFAEGIASFRAPCVWLPGNHD 96
             F + I    AP VW+ GNHD
Sbjct: 332 NGFLDPIRDLGAPYVWVRGNHD 353


>UniRef50_Q89N60 Bll3982 protein n=1 Tax=Bradyrhizobium japonicum RepID=Q89N60_BRAJA
          Length = 280

 Score = 43.5 bits (101), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 63/239 (26%), Positives = 99/239 (41%), Gaps = 41/239 (17%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQD-QSSAAY 74
           R+ QI+DTHL  ++   L+    +      ++A RP     DL++ TGD++ D  +S   
Sbjct: 5   RLTQISDTHL-GRRFPGLIA--NFHRVCEHIDADRP-----DLVINTGDVSFDGPTSRDD 56

Query: 75  QHFAEGI-ASFRAPCVWLPGNHDF--QPAMYSALQDAGISPAKRV----FIGEQ------ 121
             FA+G+  +    C +LPGNHD    P          +S A R      IGE       
Sbjct: 57  VVFAKGLHDALPVTCRYLPGNHDIGDNPTAIGPAPKPPVSEAYRQQFRDIIGEDHWSFEA 116

Query: 122 --WQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLD--- 176
             W  + L++ V           Q +WL +++A    R   L LH    P   +  D   
Sbjct: 117 AGWCFIGLNTLVMNSGLA-FEAAQFDWLTQEIARTNGRPVALFLHK---PVFLNLPDDPE 172

Query: 177 --QHSLRNA-----GELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFK 228
             + S+R         L  + A+   ++ +  GH+HQ  D  +   R +  PS  V FK
Sbjct: 173 TPETSIRYVPQPARARLIEMFARV-DLRLIASGHVHQRRDFTFRHTRHVWAPS--VGFK 228


>UniRef50_Q01N63 Metallophosphoesterase n=1 Tax=Candidatus Solibacter usitatus
           Ellin6076 RepID=Q01N63_SOLUE
          Length = 272

 Score = 43.5 bits (101), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 52/206 (25%), Positives = 83/206 (40%), Gaps = 19/206 (9%)

Query: 27  AQKHEALLGVNTWESYQAVLEAI--RPHQHEFDLIVATGDLAQD----QSSAAYQHFAEG 80
           A+ H  LLG  T E+   + E +  +    +   +++ GD  Q      + + +Q     
Sbjct: 23  AEFHFVLLGDRTGEAQAGIFEKVLRQAAATKPAFLLSVGDTIQGLHDATAESEWQEVDRI 82

Query: 81  IASFR-APCVWLPGNHDFQPAMYSAL--QDAGISPAKRVFIGEQWQILLLDSQVFGVPHG 137
           +A +R  P    PGNHD   A    L  + AG  P    F  +     ++D+        
Sbjct: 83  LAPYRRIPLYLAPGNHDIWSAESERLFRRHAG-HPPHYSFDYDGAHFAVVDNSRSDAMTA 141

Query: 138 ELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVK 197
           E    ++EWLE  L D       +++ H P     SWL   +L N       +AK   V 
Sbjct: 142 E----EMEWLEADLRDHETADVKMVISHRP-----SWLIDAALGNTNSALHRMAKRYDVC 192

Query: 198 YLLCGHIHQELDLDWNGRRLLATPST 223
            ++ GH+HQ +  +  G    A PS 
Sbjct: 193 CVIAGHVHQLIHAELEGVTYFAAPSA 218


>UniRef50_A6Q7J3 Putative uncharacterized protein n=2 Tax=unclassified
           Epsilonproteobacteria RepID=A6Q7J3_SULNB
          Length = 281

 Score = 43.5 bits (101), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 49/230 (21%), Positives = 95/230 (41%), Gaps = 36/230 (15%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQD--QSS 71
           R++ + ITD+H+     E++      E+ + ++  +  +    D ++  GD   +  + +
Sbjct: 33  RLKFIHITDSHMDLSNDESV------EAMELMVAFVNKNYPGLDFVLFGGDNFNNNVKGN 86

Query: 72  AAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFI--------GEQW- 122
           +    F E I     P   + GN +  P    ++    +   K +F+        G+ W 
Sbjct: 87  SDALKFKEIIGKLHCPSYVVRGNKESSPKPNDSIH---LDEFKSLFMDDKALTVRGKDWL 143

Query: 123 ------QILLLDSQVFGVPHGELSEFQLEWLERKL-ADAPERHTLLLLHHHPLP---AGC 172
                 QIL LDS +    +G  ++  + + ++ L A  P     ++L+HHP      G 
Sbjct: 144 LEKKGVQILGLDSCIENANNGIYTQETIHFAKKVLNAGKPS----IILNHHPYTNYWKGT 199

Query: 173 SWLDQHS--LRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLAT 220
              D H   L N  E+   L  +P++   L GH H +     N  +++ T
Sbjct: 200 KEKDLHKYVLNNTKEVQQALFSYPNLMLTLSGHKHIDSVTQINHVKVVVT 249


>UniRef50_B9TNQ0 Putative uncharacterized protein (Fragment) n=1 Tax=Ricinus
           communis RepID=B9TNQ0_RICCO
          Length = 257

 Score = 43.5 bits (101), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 50/235 (21%), Positives = 91/235 (38%), Gaps = 41/235 (17%)

Query: 55  EFDLIVATGDLAQDQSS----------AAYQHFAEGIASFRAPCVWLPGNHDF------- 97
           + D+++  GD+  D +              Q+  +   S   P  +  GNHD        
Sbjct: 22  KVDMVLNGGDIVFDMNKENISTINDQWKLVQNIMKNECSL--PVHYCLGNHDIWWYEDDK 79

Query: 98  QPAMYS---ALQDAGISPAKRVFIGEQWQILLLDSQVFGVPH----GELSEFQLEWLERK 150
             A+Y    AL    +       +   W+I++LDS    + +    G+L + QL WL  +
Sbjct: 80  GQAIYGKKYALDKLQLVKPYYSLVKNGWKIIVLDSVHLDIDNTWYIGKLGDEQLNWLSDE 139

Query: 151 LADAPERHTLLLLHHHPLPAGCSWLDQHSLRN----AGELDTVLAKF-------PHVKYL 199
           L        ++++ H P+      ++   +       G++ T  AK        P+VK  
Sbjct: 140 LKATDANMPVMVMSHIPILTALLMIEDDIVNKWTMLGGDMHTDTAKIINLFYRHPNVKLC 199

Query: 200 LCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTL 254
           + GH+H    + +N    L   +    +       T    APG+  ++L+ADGT 
Sbjct: 200 VSGHLHMRDKVVYNNVTYLCNGAVSGAWWEGNRRET----APGYGLIDLYADGTF 250


>UniRef50_Q64Z92 Serine/threonine protein kinase related protein n=12
           Tax=Bacteroidales RepID=Q64Z92_BACFR
          Length = 621

 Score = 43.5 bits (101), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 50/249 (20%), Positives = 102/249 (40%), Gaps = 38/249 (15%)

Query: 7   LPLAGEARV----RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVAT 62
           LP+A  A+V    R  Q+TD HL     +        E  +  +E I       D ++ T
Sbjct: 16  LPVATRAQVTGSFRFAQLTDIHLNPNNPKPT------EDLKRSVEQINATPG-VDFVLVT 68

Query: 63  GDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQW 122
           GDL ++            +   +     +PGNH+      +   D+G +    +F GE++
Sbjct: 69  GDLTEEGDRTTMLVVKSILDQLKVKYYVIPGNHE------TKWSDSGCTAFSEIFGGERF 122

Query: 123 QI-----LLL---DSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAG--C 172
           +      L L      +  + +G +    + W+++++    +   ++L+ H+P+  G   
Sbjct: 123 KFEHKGFLFLGFNSGPLMRMAYGHVVPQDITWMKQEMDKVGKDKPVILVTHYPMQDGDVD 182

Query: 173 SWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCS 232
           +W D           T   +  +++  + GH H+   L ++G   + T S  ++ K   S
Sbjct: 183 NWYDV----------TDAVRPYNIRTFIGGHYHRNRFLSYDGIPGILTRSN-LRDKNGSS 231

Query: 233 NFTLDTIAP 241
            +++  I P
Sbjct: 232 GYSIFDITP 240


>UniRef50_A6G589 Putative uncharacterized protein n=1 Tax=Plesiocystis pacifica
           SIR-1 RepID=A6G589_9DELT
          Length = 431

 Score = 43.5 bits (101), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 40/164 (24%), Positives = 64/164 (39%), Gaps = 18/164 (10%)

Query: 60  VATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIG 119
           V  GDL +  +   +  FAE +     P   +PGNHD     Y    +    P    F  
Sbjct: 221 VMAGDLTETATEEEFIAFAEALEPASFPIALVPGNHDVYDG-YQPHYNLAFGPGNYAFDV 279

Query: 120 EQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLP--AGCSWLDQ 177
               + +LD+       G L+   +  L +  A   + H+L ++HH P    +   W D+
Sbjct: 280 CDSHLAMLDTG-----SGSLAPSIIGRLPQLFAKGEQAHSLTVMHHPPYAELSAAGWSDE 334

Query: 178 HSLRNAGELDTVLAKFPHV--KYLLCGHIH--QELDLDWNGRRL 217
                      +L +F H     ++ GH H   E DL+  GR +
Sbjct: 335 AMAM------IMLGEFAHQDGDAVIAGHAHMLDEFDLNVAGRDI 372


>UniRef50_A4A1K6 Ser/Thr protein phosphatase family protein (Fragment) n=1
           Tax=Blastopirellula marina DSM 3645 RepID=A4A1K6_9PLAN
          Length = 269

 Score = 43.5 bits (101), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 68/242 (28%), Positives = 97/242 (40%), Gaps = 44/242 (18%)

Query: 20  ITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQS-SAAYQHFA 78
           ++DTH+          VN   + Q  +  I     +   ++  GD A      A Y +FA
Sbjct: 44  LSDTHIPKNAEVTAREVNMTSNLQQGVREINQLPSKPAAVLFNGDCAYLSGLPADYANFA 103

Query: 79  EGIASF---RAPCVWLPGNHDFQPAMYSALQ----DAGISPAKRVFIGEQWQI--LLLDS 129
           + I      +       GNHD  PA Y AL+    +  +  +K V I E   +   LLDS
Sbjct: 104 QCIQPLIDAQQELHMTMGNHDNIPAFYDALKTQRPEQPLVESKHVSILETPYVNFFLLDS 163

Query: 130 QV-FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPL-----PAGCSWLDQHSLRNA 183
            +   V  GEL + QL+WL  +L DA      +++ HH L     P G +W         
Sbjct: 164 LMKTNVVTGELGDAQLKWLSDEL-DARADKPAIIMAHHTLQKVAPPEGKAW--------G 214

Query: 184 GELDTVLAKF-------PHVKYLLCGHIHQELDLDWNGRR-----LLATPSTCVQFKPHC 231
           G LDT  AKF         VK  + GH H      W+  R     L+  P++   F P  
Sbjct: 215 GILDT--AKFLELMHAKKQVKAYVFGHSHV-----WSHARDGDLHLINLPASAYVFNPTQ 267

Query: 232 SN 233
            N
Sbjct: 268 PN 269


>UniRef50_B1R0V9 Ser/Thr protein phosphatase family protein n=3 Tax=Clostridium
           RepID=B1R0V9_CLOBU
          Length = 337

 Score = 43.1 bits (100), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 37/190 (19%), Positives = 74/190 (38%), Gaps = 24/190 (12%)

Query: 42  YQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFA----EGIASFRAPCVWLPGNHDF 97
           +Q  ++ I+    + D ++  GD      ++ Y+       + I +  +  +   GNH+F
Sbjct: 78  FQDSVDDIKSTDIKLDALILNGDTVDQGIASQYEQMKNAIQKNINNLPSTIIKNIGNHEF 137

Query: 98  QPAMYSALQDAGISPAKRVFIG-------------EQWQILLLDSQVFGVPHGE-----L 139
               +       +    + ++               Q+  + L S+    P        +
Sbjct: 138 YDYDHGNKSKEDVDEKIQKYLDFAQEKNVYHDKWINQYHFISLGSEDGNSPTCNSTSAFI 197

Query: 140 SEFQLEWLERKLADAPER-HTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKY 198
           S  Q+ WLE KLA+  E+   + +  H PL     W D      +  L+ +++K+P V  
Sbjct: 198 SNTQIAWLEEKLAENYEKGRPIFVFLHQPLILNWGWGDIPGTNVSSNLNNIISKYPEV-I 256

Query: 199 LLCGHIHQEL 208
           L   H H++L
Sbjct: 257 LFNSHTHKQL 266


>UniRef50_C0EE22 Putative uncharacterized protein n=1 Tax=Clostridium methylpentosum
           DSM 5476 RepID=C0EE22_9CLOT
          Length = 287

 Score = 43.1 bits (100), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 35/124 (28%), Positives = 58/124 (46%), Gaps = 17/124 (13%)

Query: 12  EARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
           + R++++Q++D H      +   G +    Y+ V  + RP     DLIV TGDL  D  +
Sbjct: 39  KNRMKLVQLSDLH------DKQFGKDNRRLYRMV-ASCRP-----DLIVFTGDLVHDAKN 86

Query: 72  AAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQV 131
            +      G  +  AP V++PGNH+ +  +YS +     +   RV         L+ +QV
Sbjct: 87  ISPAIEFLGRLTKLAPVVYIPGNHEHRSGLYSEILAGLKTQGVRVLADA-----LISTQV 141

Query: 132 FGVP 135
            G P
Sbjct: 142 CGNP 145


>UniRef50_UPI000169559C enhancin family protein n=3 Tax=Paenibacillus larvae subsp. larvae
           BRL-230010 RepID=UPI000169559C
          Length = 870

 Score = 43.1 bits (100), Expect = 0.011,   Method: Composition-based stats.
 Identities = 50/213 (23%), Positives = 83/213 (38%), Gaps = 41/213 (19%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +  + I+DTH            N  +   A+ +AI   Q+  D+I  TGDL +    + Y
Sbjct: 36  ISFMAISDTH----------APNDIKIKNALNDAI---QNNVDVIFLTGDLVEIAYESNY 82

Query: 75  QHFAEGIASFRAPCVWLP-GNHD-------FQPAMYSALQDAGISPAKRVFIGEQWQILL 126
           + F + + S   P  +   GNHD       F  A    L+  G+           +  ++
Sbjct: 83  ESFIKAMNSVPHPKTYYALGNHDVRWLSGDFDEAKEKFLKYTGMPGVYYDKWINGYHFIV 142

Query: 127 LDSQVFGVPHGELSEFQLEWLERKLA-DAPERHTLLLLHHHPL-------------PAGC 172
           L ++       + S+ QL WLE KLA D      + + +H PL             P G 
Sbjct: 143 LGTEKALKDQADFSDKQLAWLEAKLAEDTDPNKPIFVFNHTPLFNTVPDSYWEGYQPGGD 202

Query: 173 SWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIH 205
             + Q       ++  +LA +P   + + GH H
Sbjct: 203 DGIIQDE-----QVKNILANYPQTVF-ISGHTH 229


>UniRef50_UPI0001745388 Ser/Thr protein phosphatase family protein n=1 Tax=Verrucomicrobium
           spinosum DSM 4136 RepID=UPI0001745388
          Length = 302

 Score = 42.7 bits (99), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 65/246 (26%), Positives = 101/246 (41%), Gaps = 22/246 (8%)

Query: 20  ITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQS-SAAYQHFA 78
            +DTH+ A       GV    + ++ +  +         ++ +GD A  +   A YQ   
Sbjct: 46  FSDTHIDADPLAVSRGVTMAANLRSCVAEVLARAERPAGLILSGDCAHLKGMRADYQTLK 105

Query: 79  ---EGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPA-KRVFIGEQ------WQILLLD 128
              + + + + P   L GNHD + A+   L D   SPA    F+  Q      W   LLD
Sbjct: 106 PLLQPLVAAKLPVHLLMGNHDDRVAVTEVL-DCATSPAVPSRFVSVQETPHANW--FLLD 162

Query: 129 S--QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGEL 186
           S  +V   P G L   QL WL R+L    +R  ++++HH+            +L ++  L
Sbjct: 163 SLDKVNSTP-GVLGGEQLAWLGRELDARSDRPAVIVVHHN---ITLQESKTDALLDSTSL 218

Query: 187 DTVLAKFPHVKYLLCGHIHQ-ELDLDWNGRRLLATPSTCVQFKPHCSN-FTLDTIAPGWR 244
             +L     VK  + GH H+     D +G   +  P     FK    N + L T+ P   
Sbjct: 219 LELLRPRRQVKACIYGHTHRWSHTEDESGLHFINLPPVAYVFKQEFPNGWVLATLQPDAL 278

Query: 245 TLELHA 250
            LEL A
Sbjct: 279 RLELRA 284


>UniRef50_Q2SPP8 Predicted phosphohydrolase n=1 Tax=Hahella chejuensis KCTC 2396
           RepID=Q2SPP8_HAHCH
          Length = 795

 Score = 42.7 bits (99), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 60/236 (25%), Positives = 98/236 (41%), Gaps = 39/236 (16%)

Query: 3   SLLTLPLAGEA--RVRILQITDTHLFAQKHEALLGVNTWESY-QAVLEAIRPHQ--HEFD 57
           +  T P AG+   + RI+ ++DT L   ++  +L     + + Q   +A +P        
Sbjct: 130 AFKTWPQAGDGVEQARIIALSDTQLDRDEYAKVLTNVVNQGFLQHECDAAQPQTCAENIA 189

Query: 58  LIVATGDLAQDQSSAAYQHFAEGIASFRA------PCVWLPGNHDFQPAMYSALQDAGIS 111
            I  +GD+ Q       QH+ E +    A      P V +PGNHD+       L  + ++
Sbjct: 190 AITISGDVVQ--VGGNRQHWREQLFGSLAAITPYVPLVTVPGNHDYYSDAELRLYRSYMA 247

Query: 112 PAKRVFIG--EQW--------QILLLDSQVFGVPHGELSE----FQLEWLERKLADAP-- 155
           P +   IG  ++W        +++ LDS      HG  +      Q +WL+  L DA   
Sbjct: 248 PPENGSIGYEDKWYYLDYLDLRLVGLDSYSISGAHGAFNRDTLAVQRQWLKETLNDAEVQ 307

Query: 156 ERHTLLLLHHHPLPAGC---SWLDQHSLRN---AGELDTVLAKFPHVKYLLCGHIH 205
            +H +L + HH    GC    W    S+ +     EL+   A+   V   L GH H
Sbjct: 308 GKHFVLGMFHH----GCLSEMWNVGESIGSCEMVAELEQYSARTGAVTGHLFGHTH 359


>UniRef50_Q6LRK7 Putative uncharacterized protein n=2 Tax=Photobacterium profundum
           RepID=Q6LRK7_PHOPR
          Length = 247

 Score = 42.7 bits (99), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 54/226 (23%), Positives = 94/226 (41%), Gaps = 30/226 (13%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQH-----EFDLIVATGDLAQDQ 69
           +RI Q++D HL     EA   +            +R  QH     +  +++ TGDL  + 
Sbjct: 1   MRIYQVSDCHLQTGNTEASANL------------VRALQHIEGNGDGAILLLTGDLVCNP 48

Query: 70  SSAAYQHFAEGIASFR--APCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLL 127
           S   Y+HF E I +    +    + GNHD    M +  + + I   K V +    +++ +
Sbjct: 49  SVDVYEHFREIIETHVSISEIYAIAGNHDDFEMMKAVFKSSRIMVKKTVKLAIGCRLIFV 108

Query: 128 DSQ---VFGVP--HGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRN 182
           DS    +  +P   G +S   L  L++     P   +++++HH  +  G  W  Q  + N
Sbjct: 109 DSSQKPLTNMPLGSGRVSNKDLSLLKKWSRKTP---SIVVVHHPVVDVGTEWFTQIGIEN 165

Query: 183 AGELDTVLAKFPHVKYLLCGHIHQELDLDWN-GRRLLATPSTCVQF 227
              +  V A   H   ++ GH H    +    G   +  P+TC  F
Sbjct: 166 KAAV--VRAIHHHTLSVISGHAHSFFKVPVKEGISQVVCPATCYGF 209


>UniRef50_Q03NU9 Predicted phosphohydrolase n=1 Tax=Lactobacillus brevis ATCC 367
           RepID=Q03NU9_LACBA
          Length = 288

 Score = 42.7 bits (99), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 54/204 (26%), Positives = 84/204 (41%), Gaps = 17/204 (8%)

Query: 11  GEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQS 70
           G  R  I+ I+D  L    ++ L      +  Q + + +  HQ   DLIV +GDL     
Sbjct: 5   GMNRFTIVHISDIDLTMDDNQRL----ATQPLQRIFDDLEDHQVAADLIVLSGDLLIGGD 60

Query: 71  SAAY----QHFAEGIASFRAPCVWLPGNHDFQPAM---YSALQDAGISPAKRVFIGEQWQ 123
              Y    Q+  +     +     L G+ D + A    Y A+        K+V   +   
Sbjct: 61  QQGYRQLHQYLQQQERRLQVTIQVLLGDRDDREAFNRGYLAVAHQPYYADKQVH--QNMD 118

Query: 124 ILLLDSQ-VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHS-LR 181
              LDS+       G L   QL+WL + L  AP R   + L HHPL A      +++ L+
Sbjct: 119 FYFLDSKWELNKSAGWLDRPQLDWLNKNLHLAPRRRAFIFL-HHPLDAPALRDMRYTLLQ 177

Query: 182 NAGELDTVLAKFPHVKYLLCGHIH 205
           N  EL  +L    ++  +  GH+H
Sbjct: 178 NNRELLAILHGH-NIGGIFTGHLH 200


>UniRef50_Q1DCU4 Ser/Thr protein phosphatase family protein n=2 Tax=Cystobacterineae
           RepID=Q1DCU4_MYXXD
          Length = 290

 Score = 42.7 bits (99), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 53/181 (29%), Positives = 77/181 (42%), Gaps = 31/181 (17%)

Query: 55  EFDLIVATGDL---AQDQSSAAYQHFAEGIASFRAPCVWLPGNHD-FQPAMYSALQDA-- 108
           + D  + +GDL   A D   +  +     +A     C  +PGNHD F P  +   + A  
Sbjct: 67  QVDHFILSGDLTAYALDAEFSGARQSLGALAEDPRRCTVIPGNHDVFTPGSHRTGRFAKY 126

Query: 109 ---------------GISPAKRVFIGEQWQILLLDSQV---FGVPHGELSEFQLEWLERK 150
                          G  P  R+   E   + LL ++V    G+ +G + E QL  L   
Sbjct: 127 FGHLLESDLPEYRREGAFPFVRLLGTEAAVVGLLSARVPRTPGLSYGVIGEAQLGGLAAL 186

Query: 151 LADA--PERHTLLLLHHHPL-PAGCSWLDQHSLRNAGELDTVLAKFPHVKY-LLCGHIHQ 206
           L DA    R  L+++HH PL P G      H LR+A   D +L   P  +Y +L GHIH+
Sbjct: 187 LKDARLEGRAILVVVHHAPLNPHGRPDRWHHGLRDA---DALLKLLPGPRYAVLHGHIHR 243

Query: 207 E 207
            
Sbjct: 244 R 244


>UniRef50_D2PXP9 Metallophosphoesterase n=1 Tax=Kribbella flavida DSM 17836
           RepID=D2PXP9_9ACTO
          Length = 1213

 Score = 42.7 bits (99), Expect = 0.015,   Method: Composition-based stats.
 Identities = 57/241 (23%), Positives = 98/241 (40%), Gaps = 48/241 (19%)

Query: 20  ITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAE 79
           + D H+ AQ  E +  +N               + +   I  +GDL  + + A ++ +  
Sbjct: 162 VADPHVNAQLPEQITEINA-------------TRQDLAFIQVSGDLTNNATDAEFEFYKA 208

Query: 80  GIASFRAPCVWLPGNHDFQP-AMYSALQDAGISPAKRVFIGEQW--------QILLLDSQ 130
             A+ + P     GNH++   A Y+A  D       R  +G +W          L+L++ 
Sbjct: 209 STANSKVPVWPAVGNHEYAAGATYAARID-----NYRRHVGPEWYSFDYADRHFLVLENN 263

Query: 131 VFGVPHGELSEFQLEWLERKLA-DAPERHTLLLLHHHPL--PAGCSWLDQHSLRNAGELD 187
               P  E    QLEW++  LA +A     L++L H P+  P G       S     E  
Sbjct: 264 -GAAPFAE----QLEWVKADLARNAGRGKRLVVLTHQPMNVPFG-------SPSVYDEYG 311

Query: 188 TVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLE 247
            VL ++   + +L GH H   D++ N     A   T    +   S++T+D    G+R + 
Sbjct: 312 KVLEQY-RAELILVGHEHSN-DVEPNS----AFAGTAKHIQTASSSYTIDNSPRGFRFVH 365

Query: 248 L 248
           +
Sbjct: 366 M 366


>UniRef50_C5SJD5 Metallophosphoesterase n=1 Tax=Asticcacaulis excentricus CB 48
           RepID=C5SJD5_9CAUL
          Length = 257

 Score = 42.4 bits (98), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 62/281 (22%), Positives = 104/281 (37%), Gaps = 54/281 (19%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +RI  I+D H  A            E+  + L  + P     DL+VA+GD+ QD + A +
Sbjct: 1   MRIAHISDLHFGAHDRRVT------ETLISTLIELEP-----DLVVASGDITQDATVAEF 49

Query: 75  QHFAEGIASFRAPCVWLPGNHD-----------------------FQPAMYSALQD-AGI 110
              +E       P   +PGNHD                        +P + + L D  GI
Sbjct: 50  VEASEFFKLLPMPAFVIPGNHDLPGLDLRRFIQPWKRYRDHIARELEPELQADLVDIKGI 109

Query: 111 SPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPA 170
           + A+ +     W             +G +S  Q   +    A +     +L +HH PL  
Sbjct: 110 NSARMILPSLNWA------------YGSISARQRHDIADFFAASTTPWRVLTVHHPPLNP 157

Query: 171 GCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPH 230
               LD  +L N G+    L +   V  +L GH H      +   R++   +T       
Sbjct: 158 PEFPLDV-TLFNKGKFLETLGE-QKVDIVLSGHQHHA----YVETRIMNGHTTLFVCAST 211

Query: 231 CSNFTLDTIAPGWRTLELHADGTLTTEVHRLADTRFQPDTA 271
             +  +     G+  L+   D ++  E+ +L+  RF   +A
Sbjct: 212 AMSVRIRKQPQGFNLLDF-KDKSVRIELRQLSGDRFMTQSA 251


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_P0AEW5 Protein icc n=161 Tax=Gammaproteobacteria RepID=...   388   e-106
UniRef50_P44685 Protein icc homolog n=27 Tax=Pasteurellaceae Rep...   329   7e-89
UniRef50_C4L9C4 Calcineurin phosphoesterase domain protein n=3 T...   327   3e-88
UniRef50_A1SZX9 Cyclic AMP phosphodiesterase n=2 Tax=Psychromona...   312   6e-84
UniRef50_Q0VLK4 Icc protein, putative n=2 Tax=Alcanivorax RepID=...   312   7e-84
UniRef50_Q2S9N2 Predicted phosphohydrolase n=1 Tax=Hahella cheju...   311   2e-83
UniRef50_Q1N2L2 Metallophosphoesterase n=1 Tax=Bermanella marisr...   311   2e-83
UniRef50_A1TYT4 Calcineurin phosphoesterase C-terminal domain pr...   309   6e-83
UniRef50_Q4KJ96 Cyclic AMP phosphodiesterase n=25 Tax=Bacteria R...   307   2e-82
UniRef50_C6AKV1 Icc n=6 Tax=Pasteurellaceae RepID=C6AKV1_AGGAN        307   3e-82
UniRef50_B8HUH6 Metallophosphoesterase n=2 Tax=Chroococcales Rep...   305   1e-81
UniRef50_A4BSE9 Ser/Thr protein phosphatase n=1 Tax=Nitrococcus ...   302   6e-81
UniRef50_B0C4F0 3',5'-cyclic-nucleotide phosphodiesterase n=1 Ta...   299   7e-80
UniRef50_Q7MNX9 Cyclic AMP phosphodiesterase n=60 Tax=Gammaprote...   298   2e-79
UniRef50_A0YY40 3',5'-cyclic-nucleotide phosphodiesterase n=1 Ta...   297   2e-79
UniRef50_D2U2B8 Cyclic 3',5'-adenosine monophosphate phosphodies...   297   2e-79
UniRef50_A6F721 Icc protein-like protein n=1 Tax=Moritella sp. P...   296   5e-79
UniRef50_A4B8Z0 Putative uncharacterized protein n=1 Tax=Reineke...   294   2e-78
UniRef50_Q8YLG0 3',5'-cyclic-nucleotide phosphodiesterase n=3 Ta...   291   2e-77
UniRef50_UPI0001698C6A Calcineurin phosphoesterase C-terminal do...   288   1e-76
UniRef50_A4A8X3 Icc protein n=2 Tax=unclassified Gammaproteobact...   286   4e-76
UniRef50_B7S0L2 Calcineurin-like phosphoesterase C-terminal doma...   285   8e-76
UniRef50_A0Y9K0 Cyclic AMP phosphodiesterase n=1 Tax=marine gamm...   283   4e-75
UniRef50_Q12J78 Metallophosphoesterase n=21 Tax=Shewanella RepID...   283   5e-75
UniRef50_Q21NU3 Metallophosphoesterase n=3 Tax=Gammaproteobacter...   281   2e-74
UniRef50_C5SEA9 Calcineurin phosphoesterase domain protein n=1 T...   280   4e-74
UniRef50_B8GLR4 Icc protein n=1 Tax=Thioalkalivibrio sp. HL-EbGR...   279   6e-74
UniRef50_C7R6J1 Metallophosphoesterase n=1 Tax=Kangiella koreens...   278   1e-73
UniRef50_Q606D3 Cyclic AMP phosphodiesterase n=1 Tax=Methylococc...   274   2e-72
UniRef50_A3M1D0 Cyclic 3'5'-adenosine monophosphate phosphodiest...   273   5e-72
UniRef50_Q3JEM1 Metallophosphoesterase n=2 Tax=Nitrosococcus oce...   269   7e-71
UniRef50_B5JTJ8 Metallophosphoesterase n=1 Tax=gamma proteobacte...   268   1e-70
UniRef50_Q2JPZ0 Icc protein n=2 Tax=Synechococcus RepID=Q2JPZ0_S...   265   1e-69
UniRef50_B8KUM1 Cyclic AMP phosphodiesterase n=1 Tax=gamma prote...   262   1e-68
UniRef50_Q2KTW6 cAMP phosphodiesterase n=5 Tax=Bordetella RepID=...   260   3e-68
UniRef50_A0Z341 Metallophosphoesterase n=1 Tax=marine gamma prot...   260   4e-68
UniRef50_B9ZKN4 Calcineurin phosphoesterase domain protein n=1 T...   258   2e-67
UniRef50_Q1YUP4 CAMP phosphodiesterase n=1 Tax=gamma proteobacte...   258   2e-67
UniRef50_B1XQ99 Putative 3',5'-cyclic-nucleotide phosphodiestera...   252   1e-65
UniRef50_Q0EZ19 Ser/Thr protein phosphatase n=1 Tax=Mariprofundu...   250   5e-65
UniRef50_Q0AC05 Metallophosphoesterase n=1 Tax=Alkalilimnicola e...   243   4e-63
UniRef50_C8PWU2 Calcineurin phosphoesterase domain protein n=1 T...   243   5e-63
UniRef50_Q1QUF7 Metallophosphoesterase n=1 Tax=Chromohalobacter ...   239   9e-62
UniRef50_A8ZM80 Phosphodiesterase, putative n=1 Tax=Acaryochlori...   236   6e-61
UniRef50_Q2BR54 Metallophosphoesterase n=1 Tax=Neptuniibacter ca...   235   2e-60
UniRef50_Q1Q887 Metallophosphoesterase n=2 Tax=Psychrobacter Rep...   233   5e-60
UniRef50_B1KBF2 Metallophosphoesterase n=5 Tax=Proteobacteria Re...   232   8e-60
UniRef50_Q2KTP2 Putative phosphohydrolase n=1 Tax=Bordetella avi...   232   9e-60
UniRef50_Q1MS94 Phosphodiesterase n=1 Tax=Lawsonia intracellular...   228   1e-58
UniRef50_Q3JU10 Ser/Thr protein phosphatase family protein n=72 ...   228   2e-58
UniRef50_A3RQT5 Icc protein n=4 Tax=Ralstonia solanacearum RepID...   227   3e-58
UniRef50_B3Q6B8 Metallophosphoesterase n=8 Tax=Bradyrhizobiaceae...   227   4e-58
UniRef50_Q1LDS0 Metallophosphoesterase n=10 Tax=Proteobacteria R...   227   4e-58
UniRef50_D1A354 Metallophosphoesterase n=1 Tax=Thermomonospora c...   225   9e-58
UniRef50_A6D2K7 Ser/Thr protein phosphatase family protein n=1 T...   225   2e-57
UniRef50_A1ZTZ2 Metallophosphoesterase n=1 Tax=Microscilla marin...   221   2e-56
UniRef50_B6R8M8 Ser/Thr protein phosphatase family protein n=1 T...   220   6e-56
UniRef50_A8U260 Ser/Thr protein phosphatase family protein n=1 T...   219   1e-55
UniRef50_A5WBU9 Calcineurin phosphoesterase C-terminal domain pr...   218   1e-55
UniRef50_B8J1S2 Metallophosphoesterase n=1 Tax=Desulfovibrio des...   218   2e-55
UniRef50_A4EV76 3',5'-cyclic-nucleotide phosphodiesterase, cpdA ...   216   6e-55
UniRef50_C1CX57 Putative Metallophosphoesterase; putative cAMP p...   216   7e-55
UniRef50_C6DHP5 Metallophosphoesterase n=5 Tax=Proteobacteria Re...   215   1e-54
UniRef50_A4C954 Cyclic 3',5'-adenosine monophosphate phosphodies...   215   2e-54
UniRef50_A7IH99 Metallophosphoesterase n=2 Tax=Xanthobacteraceae...   215   2e-54
UniRef50_P05675 Uncharacterized protein syc0937_d n=2 Tax=Synech...   214   3e-54
UniRef50_C8SU16 Metallophosphoesterase n=1 Tax=Mesorhizobium opp...   214   3e-54
UniRef50_B0UF90 Metallophosphoesterase n=2 Tax=Methylobacterium ...   214   3e-54
UniRef50_Q4JN56 Predicted 3',5'-cyclic-nucleotide phosphodiester...   213   3e-54
UniRef50_Q4ZTD8 Metallophosphoesterase n=4 Tax=Pseudomonas syrin...   213   4e-54
UniRef50_D2U008 3',5'-cyclic-nucleotide phosphodiesterase n=1 Ta...   213   5e-54
UniRef50_Q7NZT6 3',5'-cyclic-nucleotide phosphodiesterase n=1 Ta...   212   9e-54
UniRef50_B1A0M0 Ser/Thr protein phosphatase family protein n=3 T...   212   1e-53
UniRef50_D1U8L8 Metallophosphoesterase n=1 Tax=Desulfovibrio aes...   211   2e-53
UniRef50_Q162P5 Ser/Thr protein phosphatase family protein, puta...   211   3e-53
UniRef50_A0NY27 Metallophosphoesterase n=2 Tax=Rhodobacteraceae ...   210   3e-53
UniRef50_A9FYQ8 Phosphodiesterase n=6 Tax=Rhodobacteraceae RepID...   210   4e-53
UniRef50_A7BW21 Cyclic AMP phosphodiesterase n=1 Tax=Beggiatoa s...   210   4e-53
UniRef50_C6CXY6 Metallophosphoesterase n=1 Tax=Paenibacillus sp....   210   4e-53
UniRef50_Q89MQ1 Bll4141 protein n=1 Tax=Bradyrhizobium japonicum...   210   5e-53
UniRef50_C5T0E1 Metallophosphoesterase n=1 Tax=Acidovorax delafi...   208   1e-52
UniRef50_Q47WJ3 Cyclic AMP phosphodiesterase n=1 Tax=Colwellia p...   208   1e-52
UniRef50_Q1GM28 Metallophosphoesterase n=3 Tax=Rhodobacteraceae ...   208   2e-52
UniRef50_B9QUB7 Ser/Thr protein phosphatase family protein n=1 T...   207   3e-52
UniRef50_B6J9P9 3',5'-cyclic-nucleotide phosphodiesterase n=7 Ta...   207   3e-52
UniRef50_B6WYD4 Putative uncharacterized protein n=1 Tax=Desulfo...   207   3e-52
UniRef50_B3TB35 Putative calcineurin-like phosphoesterase n=1 Ta...   207   3e-52
UniRef50_Q2J948 Metallophosphoesterase n=5 Tax=Actinomycetales R...   207   5e-52
UniRef50_A2C6L9 Serine/threonine specific protein phosphatase n=...   206   7e-52
UniRef50_A5FX65 Metallophosphoesterase n=1 Tax=Acidiphilium cryp...   205   1e-51
UniRef50_C1AX97 3',5'-cyclic-nucleotide phosphodiesterase n=24 T...   204   3e-51
UniRef50_C6A0T0 Predicted phosphohydrolase n=6 Tax=Thermococcus ...   203   4e-51
UniRef50_B5JAZ3 Ser/Thr protein phosphatase family protein n=2 T...   203   6e-51
UniRef50_Q3AIR5 Possible ICC (3',5'-cyclic-nucleotide phosphodie...   203   6e-51
UniRef50_A4F6Q6 Cyclic nucleotide phosphodiesterase n=7 Tax=Acti...   203   7e-51
UniRef50_B0P519 Putative uncharacterized protein n=2 Tax=Clostri...   202   8e-51
UniRef50_A6U5M4 Metallophosphoesterase n=3 Tax=Rhizobiaceae RepI...   202   1e-50
UniRef50_C6BIA6 Metallophosphoesterase n=2 Tax=Ralstonia pickett...   202   1e-50
UniRef50_A0NQD3 Ser/Thr protein phosphatase family protein n=1 T...   201   2e-50
UniRef50_B7QYI4 3',5'-cyclic-nucleotide phosphodiesterase, CpdA ...   201   2e-50
UniRef50_C7S9W5 Protein icc n=17 Tax=Bacteria RepID=C7S9W5_ECOLX      200   3e-50
UniRef50_B3Q702 Metallophosphoesterase n=5 Tax=Alphaproteobacter...   200   3e-50
UniRef50_Q0FF25 Putative uncharacterized protein n=1 Tax=Rhodoba...   200   4e-50
UniRef50_A4EJU5 3',5'-cyclic-nucleotide phosphodiesterase, cpdA ...   200   5e-50
UniRef50_Q1GWA3 Metallophosphoesterase n=1 Tax=Sphingopyxis alas...   200   6e-50
UniRef50_A3WHQ7 Putative cAMP phosphodiesterase n=1 Tax=Erythrob...   199   9e-50
UniRef50_Q982B7 Mll9148 protein n=1 Tax=Mesorhizobium loti RepID...   199   1e-49
UniRef50_A5GLK1 Predicted phosphohydrolase n=4 Tax=Synechococcus...   198   2e-49
UniRef50_B4RZD1 3,5-cyclic-nucleotide phosphodiesterase n=2 Tax=...   196   6e-49
UniRef50_A4AIJ2 Putative uncharacterized protein n=1 Tax=marine ...   196   6e-49
UniRef50_D1XS68 Metallophosphoesterase n=1 Tax=Streptomyces sp. ...   196   8e-49
UniRef50_B5J8T8 Ser/Thr protein phosphatase family protein n=2 T...   196   9e-49
UniRef50_B6IT97 Phosphodiesterase, putative n=1 Tax=Rhodospirill...   195   1e-48
UniRef50_A5CN72 Putative 3',5'-cyclic-nucleotide phosphodiestera...   195   2e-48
UniRef50_A9CKB5 Putative uncharacterized protein n=2 Tax=Alphapr...   194   2e-48
UniRef50_UPI0001B53F99 metallophosphoesterase n=1 Tax=Streptomyc...   194   3e-48
UniRef50_Q2RNL1 Metallophosphoesterase n=1 Tax=Rhodospirillum ru...   194   3e-48
UniRef50_C7D8R5 Phosphodiesterase n=1 Tax=Thalassiobium sp. R2A6...   193   5e-48
UniRef50_Q5Z214 Putative phosphodiesterase n=1 Tax=Nocardia farc...   193   7e-48
UniRef50_B5K790 Metallophosphoesterase n=1 Tax=Octadecabacter an...   192   1e-47
UniRef50_C9RR52 Metallophosphoesterase n=1 Tax=Fibrobacter succi...   191   1e-47
UniRef50_Q20ZN1 Metallophosphoesterase n=1 Tax=Rhodopseudomonas ...   191   2e-47
UniRef50_C6D6T3 Metallophosphoesterase n=1 Tax=Paenibacillus sp....   191   2e-47
UniRef50_C6WAT1 Metallophosphoesterase n=1 Tax=Actinosynnema mir...   190   3e-47
UniRef50_A9DF72 Possible 3',5'-cyclic-nucleotide phosphodiestera...   190   3e-47
UniRef50_B7BFD3 Putative uncharacterized protein n=1 Tax=Parabac...   190   3e-47
UniRef50_C9CTH4 Phosphodiesterase n=6 Tax=Proteobacteria RepID=C...   190   4e-47
UniRef50_Q3IG69 Cyclic 3',5'-adenosine monophosphate phosphodies...   190   5e-47
UniRef50_Q2J3S6 Metallophosphoesterase n=5 Tax=Rhodopseudomonas ...   189   8e-47
UniRef50_A3W656 Ser/Thr protein phosphatase family protein n=3 T...   188   1e-46
UniRef50_Q28NL1 Metallophosphoesterase n=2 Tax=Rhodobacteraceae ...   188   2e-46
UniRef50_Q15YS5 Metallophosphoesterase n=1 Tax=Pseudoalteromonas...   188   2e-46
UniRef50_A3K5W8 Phosphodiesterase n=1 Tax=Sagittula stellata E-3...   186   6e-46
UniRef50_A1AWV4 Metallophosphoesterase n=5 Tax=Bacteria RepID=A1...   186   8e-46
UniRef50_D2QL03 Metallophosphoesterase n=1 Tax=Spirosoma lingual...   185   1e-45
UniRef50_A5V3T9 Metallophosphoesterase n=2 Tax=Sphingomonadaceae...   184   3e-45
UniRef50_D2PMS5 Metallophosphoesterase n=1 Tax=Kribbella flavida...   183   4e-45
UniRef50_A3JT02 Putative uncharacterized protein n=1 Tax=Rhodoba...   182   1e-44
UniRef50_D2AYX4 Metallophosphoesterase n=10 Tax=Actinomycetales ...   181   2e-44
UniRef50_Q9V2G8 Predicted phosphohydrolase, putative n=3 Tax=Pyr...   180   4e-44
UniRef50_C0WNK1 3',5'-cyclic-nucleotide phosphodiesterase n=3 Ta...   179   8e-44
UniRef50_Q8TVF8 Predicted calcineurin superfamily phosphohydrola...   178   2e-43
UniRef50_A9CI50 Putative uncharacterized protein n=1 Tax=Agrobac...   174   3e-42
UniRef50_Q0RKV8 Putative uncharacterized protein n=1 Tax=Frankia...   174   3e-42
UniRef50_A3U194 Putative uncharacterized protein n=1 Tax=Oceanic...   173   7e-42
UniRef50_D0L6V7 Metallophosphoesterase n=1 Tax=Gordonia bronchia...   173   7e-42
UniRef50_C8XD18 Metallophosphoesterase n=1 Tax=Nakamurella multi...   171   2e-41
UniRef50_A9WNR5 Putative 3',5'-cyclic-nucleotide phosphodiestera...   171   2e-41
UniRef50_A6W423 Metallophosphoesterase n=1 Tax=Kineococcus radio...   169   9e-41
UniRef50_A5FYX3 Metallophosphoesterase n=1 Tax=Acidiphilium cryp...   169   9e-41
UniRef50_C9AD97 Phosphoesterase n=3 Tax=Enterococcus casseliflav...   169   9e-41
UniRef50_C6VLV6 3',5'-cyclic-nucleotide phosphodiesterase n=3 Ta...   168   2e-40
UniRef50_C7MAF7 Predicted phosphohydrolase n=1 Tax=Brachybacteri...   167   4e-40
UniRef50_A1SEE2 Metallophosphoesterase n=2 Tax=Actinobacteria (c...   166   6e-40
UniRef50_D2EUB1 Metallophosphoesterase n=1 Tax=Bacteroides sp. D...   166   9e-40
UniRef50_Q6ACA7 Putative uncharacterized protein n=1 Tax=Leifson...   165   2e-39
UniRef50_O66909 Putative uncharacterized protein n=1 Tax=Aquifex...   164   4e-39
UniRef50_A5UK60 Predicted phosphohydrolase, calcineurin-like sup...   164   4e-39
UniRef50_A9DXP9 Putative uncharacterized protein n=1 Tax=Oceanib...   163   6e-39
UniRef50_C5CDX7 Metallophosphoesterase n=1 Tax=Kosmotoga olearia...   162   1e-38
UniRef50_Q7NJG1 Glr1871 protein n=1 Tax=Gloeobacter violaceus Re...   161   3e-38
UniRef50_D2PQZ3 Metallophosphoesterase n=1 Tax=Kribbella flavida...   161   3e-38
UniRef50_Q1AXD2 Metallophosphoesterase n=1 Tax=Rubrobacter xylan...   160   4e-38
UniRef50_C7D3F7 Predicted protein n=5 Tax=Enterococcus RepID=C7D...   160   5e-38
UniRef50_A6CD50 Cyclic 3',5'-adenosine monophosphate phosphodies...   160   5e-38
UniRef50_C6VU97 Metallophosphoesterase n=1 Tax=Dyadobacter ferme...   160   6e-38
UniRef50_C8QH10 Metallophosphoesterase n=3 Tax=Enterobacteriacea...   157   3e-37
UniRef50_C8S8V3 Metallophosphoesterase n=1 Tax=Ferroglobus placi...   157   3e-37
UniRef50_B4D428 Metallophosphoesterase n=1 Tax=Chthoniobacter fl...   156   8e-37
UniRef50_A1ZMS0 Putative uncharacterized protein n=1 Tax=Microsc...   155   2e-36
UniRef50_O27755 Transcriptional regulator Icc related protein n=...   154   3e-36
UniRef50_C7PKP5 Metallophosphoesterase n=1 Tax=Chitinophaga pine...   153   7e-36
UniRef50_B9TAV3 Putative uncharacterized protein n=1 Tax=Ricinus...   153   9e-36
UniRef50_A9A2N5 Metallophosphoesterase n=4 Tax=marine archaeal g...   153   9e-36
UniRef50_C6B6U2 Metallophosphoesterase n=2 Tax=Rhizobium legumin...   152   1e-35
UniRef50_O30241 LacZ expression regulatory protein (Icc) n=1 Tax...   151   2e-35
UniRef50_Q3Y3L7 Metallophosphoesterase n=1 Tax=Enterococcus faec...   151   2e-35
UniRef50_C2KF95 Serine/threonine protein phosphatase family prot...   151   2e-35
UniRef50_C2FYP3 Metallophosphoesterase n=1 Tax=Sphingobacterium ...   151   3e-35
UniRef50_Q1AVF9 Metallophosphoesterase n=1 Tax=Rubrobacter xylan...   150   5e-35
UniRef50_B5JMC7 Ser/Thr protein phosphatase family protein n=1 T...   149   6e-35
UniRef50_D1N465 Metallophosphoesterase n=1 Tax=Victivallis vaden...   148   2e-34
UniRef50_Q2JP63 Ser/Thr protein phosphatase family protein n=2 T...   148   2e-34
UniRef50_B5YAA1 Membrane-associated protein, putative n=2 Tax=Di...   148   2e-34
UniRef50_C5EL28 Predicted protein n=1 Tax=Clostridiales bacteriu...   147   4e-34
UniRef50_Q1C384 Regulator of lacZ n=8 Tax=Enterobacteriaceae Rep...   147   4e-34
UniRef50_B9XC60 Metallophosphoesterase n=1 Tax=bacterium Ellin51...   146   7e-34
UniRef50_D2QD99 Metallophosphoesterase n=1 Tax=Spirosoma lingual...   145   1e-33
UniRef50_C1VB71 Predicted phosphohydrolase n=1 Tax=Halogeometric...   145   2e-33
UniRef50_C7Q3U3 Metallophosphoesterase n=3 Tax=Actinomycetales R...   143   5e-33
UniRef50_B1LAV7 Metallophosphoesterase n=2 Tax=Thermotoga sp. RQ...   140   4e-32
UniRef50_Q46D43 3,5-cyclic-nucleotide phosphodiesterase n=8 Tax=...   139   8e-32
UniRef50_Q9YDE7 Putative uncharacterized protein n=1 Tax=Aeropyr...   139   1e-31
UniRef50_C5PKR3 Putative uncharacterized protein n=2 Tax=Sphingo...   136   7e-31
UniRef50_C7NWB5 Metallophosphoesterase n=1 Tax=Halomicrobium muk...   136   7e-31
UniRef50_D1B7Z2 Metallophosphoesterase n=1 Tax=Thermanaerovibrio...   135   1e-30
UniRef50_A4WK20 Metallophosphoesterase n=5 Tax=Thermoproteaceae ...   135   2e-30
UniRef50_C2E1N9 Serine/threonine protein phosphatase family prot...   134   2e-30
UniRef50_A6WWL5 Metallophosphoesterase n=1 Tax=Ochrobactrum anth...   133   8e-30
UniRef50_B9K806 Metallophosphoesterase n=1 Tax=Thermotoga neapol...   133   9e-30
UniRef50_UPI000185BF3C putative secreted protein n=1 Tax=Coryneb...   131   2e-29
UniRef50_A1HNK3 Metallophosphoesterase n=1 Tax=Thermosinus carbo...   131   2e-29
UniRef50_A6WZI2 Metallophosphoesterase n=49 Tax=Proteobacteria R...   131   3e-29
UniRef50_UPI0001BC808F hypothetical protein BacD2_17610 n=1 Tax=...   127   5e-28
UniRef50_Q2SWK2 Ser/Thr protein phosphatase family protein n=37 ...   127   5e-28
UniRef50_B2TAN8 Metallophosphoesterase n=1 Tax=Burkholderia phyt...   126   6e-28
UniRef50_Q03AS7 Predicted phosphohydrolase n=9 Tax=Lactobacillus...   124   2e-27
UniRef50_A6E4I6 Putative uncharacterized protein n=1 Tax=Roseova...   122   1e-26
UniRef50_A3WFW5 Putative uncharacterized protein n=1 Tax=Erythro...   119   9e-26
UniRef50_A0RA77 Purple acid phosphatase/fibronectin domain prote...   118   2e-25
UniRef50_C5AJE8 Metallophosphoesterase n=1 Tax=Burkholderia glum...   113   5e-24

Sequences not found previously or not previously below threshold:

UniRef50_Q5UEX4 Predicted Ser/Thr protein phosphatase family pro...   148   2e-34
UniRef50_UPI0001745388 Ser/Thr protein phosphatase family protei...   143   5e-33
UniRef50_D2QP98 Metallophosphoesterase n=1 Tax=Spirosoma lingual...   143   5e-33
UniRef50_A4A1K6 Ser/Thr protein phosphatase family protein (Frag...   140   6e-32
UniRef50_B9TNQ0 Putative uncharacterized protein (Fragment) n=1 ...   136   6e-31
UniRef50_Q64Z92 Serine/threonine protein kinase related protein ...   133   5e-30
UniRef50_C9NY92 3',5'-cyclic-nucleotide phosphodiesterase n=5 Ta...   131   2e-29
UniRef50_B8HPG6 Metallophosphoesterase n=8 Tax=Cyanobacteria Rep...   130   5e-29
UniRef50_C6X3M3 Phosphoribosylglycinamide formyltransferase n=3 ...   129   9e-29
UniRef50_Q2JHD6 Ser/Thr protein phosphatase family protein n=12 ...   128   2e-28
UniRef50_B9C147 Metallophosphoesterase n=1 Tax=Burkholderia mult...   127   3e-28
UniRef50_C8ZWM4 Phosphohydrolase n=4 Tax=Enterococcus RepID=C8ZW...   126   6e-28
UniRef50_A6DRV9 Ser/Thr protein phosphatase family protein n=1 T...   126   7e-28
UniRef50_A7C221 Metallophosphoesterase n=1 Tax=Beggiatoa sp. PS ...   126   9e-28
UniRef50_A9APX8 Metallophosphoesterase n=4 Tax=Burkholderia RepI...   126   1e-27
UniRef50_Q7NSC8 Putative uncharacterized protein n=1 Tax=Chromob...   125   1e-27
UniRef50_C7PMF7 Metallophosphoesterase n=1 Tax=Chitinophaga pine...   124   3e-27
UniRef50_UPI00016C4274 hypothetical protein GobsU_18190 n=1 Tax=...   124   3e-27
UniRef50_D1VKL8 Metallophosphoesterase n=1 Tax=Frankia sp. EuI1c...   122   1e-26
UniRef50_A0QKV9 Metallophosphoesterase n=4 Tax=Mycobacterium Rep...   122   2e-26
UniRef50_Q091L6 Ser/Thr protein phosphatase family protein n=1 T...   121   3e-26
UniRef50_A3ZYM0 Putative uncharacterized protein n=1 Tax=Blastop...   121   3e-26
UniRef50_C6XUF6 Metallophosphoesterase n=1 Tax=Pedobacter hepari...   120   5e-26
UniRef50_B3C782 Putative uncharacterized protein n=2 Tax=Bactero...   119   9e-26
UniRef50_C5SJD5 Metallophosphoesterase n=1 Tax=Asticcacaulis exc...   119   1e-25
UniRef50_D0LMB8 Metallophosphoesterase n=1 Tax=Haliangium ochrac...   118   2e-25
UniRef50_C6J7N6 Metallophosphoesterase n=2 Tax=Bacillales RepID=...   118   2e-25
UniRef50_B6YTV2 Metallophosphoesterase n=2 Tax=Thermococcus RepI...   118   3e-25
UniRef50_B6IMU0 3',5'-cyclic-nucleotide phosphodiesterase, putat...   118   3e-25
UniRef50_B1ZFT6 Metallophosphoesterase n=1 Tax=Methylobacterium ...   117   4e-25
UniRef50_Q6LRK7 Putative uncharacterized protein n=2 Tax=Photoba...   117   5e-25
UniRef50_B2IDE3 Metallophosphoesterase n=34 Tax=Bacteria RepID=B...   117   5e-25
UniRef50_A6EBB1 Putative uncharacterized protein n=2 Tax=Sphingo...   116   8e-25
UniRef50_C4WQD0 Putative uncharacterized protein n=1 Tax=Ochroba...   115   1e-24
UniRef50_Q2NGW0 Predicted phosphohydrolase n=2 Tax=Methanobacter...   115   1e-24
UniRef50_A9B0W4 Metallophosphoesterase n=1 Tax=Herpetosiphon aur...   115   2e-24
UniRef50_Q03NU9 Predicted phosphohydrolase n=1 Tax=Lactobacillus...   115   2e-24
UniRef50_B9K5P3 Putative uncharacterized protein n=1 Tax=Agrobac...   114   3e-24
UniRef50_C7PXI9 Metallophosphoesterase n=2 Tax=Actinomycetales R...   113   5e-24

>UniRef50_P0AEW5 Protein icc n=161 Tax=Gammaproteobacteria RepID=ICC_ECO57
          Length = 275

 Score =  388 bits (997), Expect = e-106,   Method: Composition-based stats.
 Identities = 275/275 (100%), Positives = 275/275 (100%)

Query: 1   MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV 60
           MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
Sbjct: 1   MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV 60

Query: 61  ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE 120
           ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
Sbjct: 61  ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE 120

Query: 121 QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL 180
           QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
Sbjct: 121 QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL 180

Query: 181 RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA 240
           RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
Sbjct: 181 RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA 240

Query: 241 PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY 275
           PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
Sbjct: 241 PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY 275


>UniRef50_P44685 Protein icc homolog n=27 Tax=Pasteurellaceae RepID=ICC_HAEIN
          Length = 274

 Score =  329 bits (844), Expect = 7e-89,   Method: Composition-based stats.
 Identities = 140/266 (52%), Positives = 186/266 (69%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
           A +  +++LQITD HLF  +   LLGVNT  S+  VL+ I+   +EFD+I+ATGDL QD 
Sbjct: 9   AEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNEFDVILATGDLVQDS 68

Query: 70  SSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDS 129
           S   Y  F E +  F  P  W+PGNHDFQP M   L    ++ AK + +GE WQ LLLDS
Sbjct: 69  SDEGYIRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGEHWQALLLDS 128

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
           QV+GVPHG+LS+ QL+ L+  L   PER+TL++LHHH LP   +WLDQH+LRN+ EL  V
Sbjct: 129 QVYGVPHGQLSQHQLDLLKETLGKNPERYTLVVLHHHLLPTNSAWLDQHNLRNSHELAEV 188

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELH 249
           LA F +VK +L GHIHQE++ +WNG +++ATP+TC+QFKP C  F+LDT+ PGWR +ELH
Sbjct: 189 LAPFTNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQPGWREIELH 248

Query: 250 ADGTLTTEVHRLADTRFQPDTASEGY 275
           +DG++ TEV R+    F P+   EGY
Sbjct: 249 SDGSIRTEVKRIQQAEFFPNMQEEGY 274


>UniRef50_C4L9C4 Calcineurin phosphoesterase domain protein n=3
           Tax=Gammaproteobacteria RepID=C4L9C4_TOLAT
          Length = 273

 Score =  327 bits (838), Expect = 3e-88,   Method: Composition-based stats.
 Identities = 137/270 (50%), Positives = 185/270 (68%), Gaps = 1/270 (0%)

Query: 6   TLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDL 65
           TL    +  VR+LQI+DTHLFA+ +  LLG+ T +S+QAVL+AI      +D+++ATGDL
Sbjct: 5   TLSKPDDGIVRLLQISDTHLFAETNRDLLGIATADSFQAVLDAITELPQTYDVVLATGDL 64

Query: 66  AQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQIL 125
           +QD S+A+YQ FA  + + + P  WLPGNHD +  M + LQ +GI P  +  +G+ WQ++
Sbjct: 65  SQDHSAASYQRFARMVTTLQKPVHWLPGNHDHRVLMQNELQVSGIRPEMQ-LVGDHWQVI 123

Query: 126 LLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGE 185
           LLDSQV+G PHG LS  QLE LE  L   PE+H L+ LHHH  P G  WLDQH L+NA +
Sbjct: 124 LLDSQVYGTPHGWLSHLQLEQLEAALLQYPEKHVLICLHHHTFPIGSIWLDQHDLKNASD 183

Query: 186 LDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRT 245
              VLA++P VK +LCGH+HQE D    G R L +PSTC+QF+P   +F+LDT++PGWR 
Sbjct: 184 FLAVLARYPRVKAVLCGHVHQEYDQYHQGIRFLTSPSTCIQFQPLSVDFSLDTMSPGWRY 243

Query: 246 LELHADGTLTTEVHRLADTRFQPDTASEGY 275
           L+L+ DG + T+V RL   +F PD  S GY
Sbjct: 244 LQLYPDGRIATQVWRLEPGQFAPDLQSTGY 273


>UniRef50_A1SZX9 Cyclic AMP phosphodiesterase n=2 Tax=Psychromonas
           RepID=A1SZX9_PSYIN
          Length = 278

 Score =  312 bits (801), Expect = 6e-84,   Method: Composition-based stats.
 Identities = 114/270 (42%), Positives = 178/270 (65%), Gaps = 1/270 (0%)

Query: 6   TLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDL 65
            L    +  +++LQITDTHLF+ +++ LLG+   ESY+AV++    +  +   +++TGDL
Sbjct: 10  KLRSDQQGCLQLLQITDTHLFSDRNKDLLGIKPAESYEAVIKHASRYSSKCQAVLSTGDL 69

Query: 66  AQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQIL 125
           +QD +  +Y  F + I +   PC WLPGNHD Q  M  +L   G++ +K++ + + WQI+
Sbjct: 70  SQDHTQQSYLDFTKQIKTLNLPCYWLPGNHDTQSVMLPSLLQEGLAQSKQI-VSDFWQII 128

Query: 126 LLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGE 185
           LLDSQV G PHG L+E QL +L++ L + P++HTL+ +HHH LP   +WLDQH L+N  +
Sbjct: 129 LLDSQVEGAPHGFLTEQQLNFLQQALTEYPDKHTLICVHHHVLPVKSAWLDQHILKNNQQ 188

Query: 186 LDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRT 245
              ++    +V+ +L GH+HQ  D+++N  R L +PSTC+QFKP+  +F +D  APG+R 
Sbjct: 189 FLELIKLHKNVRVVLSGHVHQAGDIEFNQVRFLTSPSTCLQFKPNSEDFDVDDSAPGYRY 248

Query: 246 LELHADGTLTTEVHRLADTRFQPDTASEGY 275
           L LH +GT+TT+V R+A   F P+  + GY
Sbjct: 249 LALHKNGTITTKVERVAHGEFSPNKNATGY 278


>UniRef50_Q0VLK4 Icc protein, putative n=2 Tax=Alcanivorax RepID=Q0VLK4_ALCBS
          Length = 268

 Score =  312 bits (800), Expect = 7e-84,   Method: Composition-based stats.
 Identities = 107/262 (40%), Positives = 150/262 (57%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
            +R++Q++D HLFA     LLG+NT  S   VLE IR  Q   DLI+ATGDL+QD S  +
Sbjct: 7   PLRVVQLSDCHLFADPEGKLLGLNTQFSLDKVLELIRKEQPNPDLILATGDLSQDASYES 66

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFG 133
           YQ     ++ F  P  WL GNHD    M  AL       +  V     W I++LDS + G
Sbjct: 67  YQRLDRTLSGFDVPVYWLEGNHDKPAPMLQALGAHREKMSPCVLNVGNWTIVMLDSTIPG 126

Query: 134 VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKF 193
              GEL +  L +L+  L DA   H ++ LHHHP+P  C+WLD   + +A +   V+ + 
Sbjct: 127 EVPGELFDGDLSFLDSALRDATGDHLMVCLHHHPVPMECTWLDAQVVGSADKFFQVIDRH 186

Query: 194 PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGT 253
             V+ ++ GH+HQE D   NG R++A PSTCVQFKP   +F +D  +PG+R L+LH +G 
Sbjct: 187 ERVRAIIWGHVHQEYDKHRNGVRMMAVPSTCVQFKPKSEDFAVDDASPGYRWLDLHPNGQ 246

Query: 254 LTTEVHRLADTRFQPDTASEGY 275
           + T V R+    F+ D   +GY
Sbjct: 247 IDTAVSRVEGIPFEVDFTIKGY 268


>UniRef50_Q2S9N2 Predicted phosphohydrolase n=1 Tax=Hahella chejuensis KCTC 2396
           RepID=Q2S9N2_HAHCH
          Length = 267

 Score =  311 bits (797), Expect = 2e-83,   Method: Composition-based stats.
 Identities = 108/261 (41%), Positives = 159/261 (60%), Gaps = 2/261 (0%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + ++Q+TD+HL  +    LLG+NT  S  AVL  +R +    DL++ATGD+AQD S+ AY
Sbjct: 9   LTVIQVTDSHLRREPDGTLLGMNTRRSLDAVLSLVRANHENPDLVLATGDIAQDGSTEAY 68

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
           + F E +  F+ P  W  GNHD    M  A+QD       ++F    W+++ LDS V   
Sbjct: 69  ECFHEKMLPFQCPVYWFSGNHDDPGVMAKAVQDPECLAKVKIF--GPWKLIFLDSSVRRK 126

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
            +G+L++ +L+ L+ +L     +H ++  HHHP+   C+WLD   L N  E   V+  + 
Sbjct: 127 VYGKLAKKELQLLKAELEKDQGKHVIICFHHHPVDVDCAWLDTIGLHNRDEFFAVIDAYD 186

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTL 254
           HV+ +L GHIHQE D   NG RLLATPSTCVQFKP+  +F +D +APG+R L+L+ DG +
Sbjct: 187 HVRLVLWGHIHQEYDQVRNGVRLLATPSTCVQFKPYSEDFAVDNLAPGYRWLKLYPDGRV 246

Query: 255 TTEVHRLADTRFQPDTASEGY 275
            T V R +   F+ D +S+GY
Sbjct: 247 DTSVVRASHIEFEVDLSSKGY 267


>UniRef50_Q1N2L2 Metallophosphoesterase n=1 Tax=Bermanella marisrubri
           RepID=Q1N2L2_9GAMM
          Length = 260

 Score =  311 bits (796), Expect = 2e-83,   Method: Composition-based stats.
 Identities = 107/260 (41%), Positives = 152/260 (58%), Gaps = 2/260 (0%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           + +QITD+HLF+ K   LLG++T  S  AVLE +R    ++D  + TGDL+QD +  +YQ
Sbjct: 3   KFIQITDSHLFSTKPGKLLGMDTQYSLDAVLEKLRDEHCDYDFYLCTGDLSQDGTVESYQ 62

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVP 135
           H    +A    P  W+PGNHD +P M     +      K VF    WQI++LDSQV G  
Sbjct: 63  HLKNTLAKDGKPQHWIPGNHDHRPNMVQVASEE--VEMKPVFRAGAWQIIMLDSQVPGAV 120

Query: 136 HGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPH 195
            G  SE QL+ L   L       TL+ +HHHP+   C WLD   +RN+     ++ ++ +
Sbjct: 121 GGNFSESQLQLLRDALDADSGSPTLVTMHHHPIAMECDWLDTQQIRNSQAFRDIIDQYDN 180

Query: 196 VKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLT 255
           VK +L GH+HQ+ D   NG R ++TPSTCVQF P   +F +DT  PG+R +ELH DG++ 
Sbjct: 181 VKVVLWGHVHQDSDQLINGVRFISTPSTCVQFTPESEDFDVDTCGPGYRWMELHDDGSIK 240

Query: 256 TEVHRLADTRFQPDTASEGY 275
           T V R+    F+ D + +GY
Sbjct: 241 TGVSRVEHIDFEIDYSVKGY 260


>UniRef50_A1TYT4 Calcineurin phosphoesterase C-terminal domain protein n=3
           Tax=Marinobacter RepID=A1TYT4_MARAV
          Length = 268

 Score =  309 bits (792), Expect = 6e-83,   Method: Composition-based stats.
 Identities = 110/262 (41%), Positives = 155/262 (59%), Gaps = 2/262 (0%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
            + +LQ+TD HL A    ALLGVNT +S  AV+  +  +  + DLI+ATGDL QD S  A
Sbjct: 9   PLNVLQLTDPHLMASADGALLGVNTRDSLAAVIGEVLRNHGQPDLILATGDLTQDASPEA 68

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFG 133
           Y++F E + +F  P +W+ GNHD    + +   + G    +  +I   WQ ++LDS V G
Sbjct: 69  YRYFGEQLQAFDCPSLWIAGNHDDSALLSAIAAETGSDQKQ--WIQGGWQFVMLDSSVHG 126

Query: 134 VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKF 193
              GELS  +L +L+R L++ PE   ++ LHHHP+  G  W+++  L+N      V+ + 
Sbjct: 127 KVFGELSADELSFLDRALSERPELPAMVCLHHHPVDIGSDWMEKIGLKNRDAFWQVIDRH 186

Query: 194 PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGT 253
           P V+ +L GHIHQEL+   NG  LLATPSTC+QF    S+F ++ +APG+R LEL   G 
Sbjct: 187 PQVRVVLWGHIHQELEQQRNGACLLATPSTCIQFATGSSDFAVEPLAPGYRWLELDPSGC 246

Query: 254 LTTEVHRLADTRFQPDTASEGY 275
             TEV R A   F  D  S GY
Sbjct: 247 FKTEVRRAASFEFDLDEKSTGY 268


>UniRef50_Q4KJ96 Cyclic AMP phosphodiesterase n=25 Tax=Bacteria RepID=Q4KJ96_PSEF5
          Length = 271

 Score =  307 bits (788), Expect = 2e-82,   Method: Composition-based stats.
 Identities = 115/267 (43%), Positives = 156/267 (58%), Gaps = 2/267 (0%)

Query: 9   LAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQD 68
           L     V ++Q++D+HLFA+    LLG+NT +S Q V++ +   Q   DL++ATGDL+QD
Sbjct: 7   LTAADPVLLVQLSDSHLFAETDGTLLGMNTADSLQRVIDLVLAQQPRIDLMLATGDLSQD 66

Query: 69  QSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLD 128
            +  +YQ F +      AP  WLPGNHD    M  A   +G      V     W+I LLD
Sbjct: 67  GTLESYQRFRQLTRQIAAPGRWLPGNHDEPQVMEQA--ASGSDLLDPVVDIGNWRITLLD 124

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           S V G   G L + QL+ L R L++APERH L+ LHHHP+   C+W++   LRNA  L  
Sbjct: 125 SAVPGSVPGYLQDEQLQLLTRSLSEAPERHHLVCLHHHPVSIDCAWMEPIGLRNAQALFA 184

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLEL 248
           V+  FP V+ +L GH+HQE+D      RLLA+PSTC+QF+P   +F ++   PG+R L L
Sbjct: 185 VIDAFPQVRAVLWGHVHQEIDRLRGDVRLLASPSTCIQFEPLSDDFKVEEQVPGYRWLRL 244

Query: 249 HADGTLTTEVHRLADTRFQPDTASEGY 275
             DG L T V R+    F  D  SEGY
Sbjct: 245 LPDGRLETGVQRVEGYEFTIDYGSEGY 271


>UniRef50_C6AKV1 Icc n=6 Tax=Pasteurellaceae RepID=C6AKV1_AGGAN
          Length = 274

 Score =  307 bits (787), Expect = 3e-82,   Method: Composition-based stats.
 Identities = 135/260 (51%), Positives = 181/260 (69%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           RI+QITD HLF   +  LLG+NT  S+  VL  I+  Q+ +DL++ATGDL QD S   Y 
Sbjct: 15  RIVQITDPHLFKDTNGELLGINTQASFSQVLTEIQQQQYAYDLVLATGDLVQDSSDEGYL 74

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVP 135
           HF E + +      W+PGNHDFQP M+  L    IS  K + +G++WQILLLDSQ+ GVP
Sbjct: 75  HFCESVKALEKMVFWIPGNHDFQPKMFDLLTTDNISAKKHILLGDRWQILLLDSQISGVP 134

Query: 136 HGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPH 195
           HG+LSE+QL+WL  KL + P+R++L++LHHH L    +WLDQH+LRNA EL  +LA F +
Sbjct: 135 HGQLSEYQLDWLLAKLKEYPQRYSLVVLHHHILSTHSAWLDQHNLRNAHELAYILAPFSN 194

Query: 196 VKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLT 255
           VK +L GHIHQ++D +W+G +++ATPST +QFKP  + F LDT+ PGWR +ELHADG + 
Sbjct: 195 VKGILHGHIHQQVDGEWHGYKVMATPSTGIQFKPDSNTFALDTVQPGWREIELHADGHIE 254

Query: 256 TEVHRLADTRFQPDTASEGY 275
           T V R+    F P+   EGY
Sbjct: 255 TRVKRIQHKTFLPNLQEEGY 274


>UniRef50_B8HUH6 Metallophosphoesterase n=2 Tax=Chroococcales RepID=B8HUH6_CYAP4
          Length = 266

 Score =  305 bits (782), Expect = 1e-81,   Method: Composition-based stats.
 Identities = 110/261 (42%), Positives = 149/261 (57%), Gaps = 2/261 (0%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + I+Q++DTHLFA     L+G+NT ++ +AVL+ +       DL++ TGDL+QD+S  +Y
Sbjct: 8   LHIVQLSDTHLFADLQGQLVGLNTADALKAVLDQVAQLSPRPDLLLLTGDLSQDESVQSY 67

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
            H  + +A    P  WLPGNHD   AM   L    +      F    WQ LLL+SQV G 
Sbjct: 68  THLRDWLAPLDIPVHWLPGNHDNLQAMAQVLL-PPLYSGPSTFYLGGWQFLLLNSQVPGK 126

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
            +GELS   L WLE  L   P+R +L+ LHH PL     WLD   LRN   L  ++ + P
Sbjct: 127 VYGELSPDTLLWLENNLQAHPDRPSLIALHHPPLSISTPWLDSSRLRNPEPLLELIDRHP 186

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTL 254
            VK +  GHIHQE   +  G   L++PSTCVQF P  S F +D + PG+R L L+ DG  
Sbjct: 187 QVKLVSFGHIHQEFAAERRGVIYLSSPSTCVQFLPCSSQFAIDPMPPGFRRLMLYPDGQF 246

Query: 255 TTEVHRLADTRFQPDTASEGY 275
            TEV R+    +Q D A++GY
Sbjct: 247 HTEVMRVE-FSYQFDLAAQGY 266


>UniRef50_A4BSE9 Ser/Thr protein phosphatase n=1 Tax=Nitrococcus mobilis Nb-231
           RepID=A4BSE9_9GAMM
          Length = 279

 Score =  302 bits (775), Expect = 6e-81,   Method: Composition-based stats.
 Identities = 106/266 (39%), Positives = 150/266 (56%), Gaps = 1/266 (0%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
            G   +R+LQITDTHLFA     L+GV+T  SY  V+E +       DLI+ATGDL  D 
Sbjct: 14  GGIGSLRVLQITDTHLFADLSGQLVGVDTERSYAEVMEKVLGEFWPVDLILATGDLVHDG 73

Query: 70  SSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDS 129
           S + Y+ F           + +PGNHD    M        ++ +    +G  WQ ++LDS
Sbjct: 74  SESGYRRFKSQFEDLAVRTLVIPGNHDDATIMRRIFSTGRVTWSGSALLG-AWQFVMLDS 132

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
              G   G L+  QL+ LE+ L   PE H L+ LHHHPL  GC W+D+ ++ N  EL  +
Sbjct: 133 SQLGSAAGHLARSQLQMLEQCLTSYPEHHALVCLHHHPLAIGCDWIDRIAVDNGRELFEI 192

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELH 249
           L +   V+ ++ GH+HQE +   +G RLLA+PSTCVQF+P    FT+D + PG+R L+L+
Sbjct: 193 LDRHEQVRGVVWGHVHQEFETIRHGVRLLASPSTCVQFRPGQQEFTIDDVPPGFRWLQLY 252

Query: 250 ADGTLTTEVHRLADTRFQPDTASEGY 275
           ADG + T + R+   +   D   EGY
Sbjct: 253 ADGRIKTSIIRVDAAQGGVDLDCEGY 278


>UniRef50_B0C4F0 3',5'-cyclic-nucleotide phosphodiesterase n=1 Tax=Acaryochloris
           marina MBIC11017 RepID=B0C4F0_ACAM1
          Length = 265

 Score =  299 bits (766), Expect = 7e-80,   Method: Composition-based stats.
 Identities = 103/267 (38%), Positives = 150/267 (56%), Gaps = 2/267 (0%)

Query: 9   LAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQD 68
           +   + + I Q++D HLFA     LLG+NT+ S +AV++ ++      D ++ TGDLAQD
Sbjct: 1   MKKSSPLLIAQLSDLHLFANPDRDLLGLNTFSSLEAVVQKLKQLPVLPDQLLLTGDLAQD 60

Query: 69  QSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLD 128
           ++  AYQ     IA  + P  WLPGNHD  P M +    A    A + +    W  LLLD
Sbjct: 61  ETPIAYQQIQSLIAPLQIPTYWLPGNHDHLPTMQATF-TAPSFQAHKSYQMGDWHFLLLD 119

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           S V G  +G LS   L+WL ++L     + TL+ LHH P      WLDQ  L+N+ +L  
Sbjct: 120 SSVTGKVYGGLSPESLDWLNQELEQCDPQPTLIALHHPPFAIKSDWLDQIGLQNSDDLFA 179

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLEL 248
           +L +  HVK ++ GHIHQ+ +        L+TPSTC+QF PH   F LD   PG+R  +L
Sbjct: 180 ILDRHSHVKLVVFGHIHQQFEHQRRSIHYLSTPSTCIQFAPHSKTFALDHAQPGFRLFQL 239

Query: 249 HADGTLTTEVHRLADTRFQPDTASEGY 275
           + DG+  TE+HR+   +   D +++GY
Sbjct: 240 YGDGSFETEIHRVMFEK-TLDFSAKGY 265


>UniRef50_Q7MNX9 Cyclic AMP phosphodiesterase n=60 Tax=Gammaproteobacteria
           RepID=Q7MNX9_VIBVY
          Length = 274

 Score =  298 bits (763), Expect = 2e-79,   Method: Composition-based stats.
 Identities = 138/265 (52%), Positives = 188/265 (70%)

Query: 11  GEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQS 70
            E  +++LQITDTHLFA    +LL V T +S+QAV+E +     EFD ++ATGD++QD S
Sbjct: 10  SENSIKLLQITDTHLFASDEGSLLSVKTLQSFQAVVEQVMARHVEFDYLLATGDISQDHS 69

Query: 71  SAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQ 130
           +A+YQ FA+GIA     C WLPGNHD++P M S L    I+  ++V +   WQ++LLDSQ
Sbjct: 70  AASYQRFADGIAPLEKACFWLPGNHDYKPNMSSVLPSPQITTPEQVELNAHWQLILLDSQ 129

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
           V GVPHG LS+ QL  LE  L  +PE++TL+LLHHHPL  G +WLDQH+L++A     ++
Sbjct: 130 VVGVPHGRLSDQQLSMLEHHLQASPEKNTLILLHHHPLLVGSAWLDQHTLKDAEAFWQIV 189

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHA 250
            +FP VK ++CGH+HQ++++   G R++ATPSTCVQFKP   +F LDT++PGWR L LHA
Sbjct: 190 ERFPMVKGIVCGHVHQDMNVMHKGIRVMATPSTCVQFKPQSDDFALDTVSPGWRELTLHA 249

Query: 251 DGTLTTEVHRLADTRFQPDTASEGY 275
           +G +TT+V RLA   F PD  S GY
Sbjct: 250 NGEITTQVQRLASGSFLPDFTSSGY 274


>UniRef50_A0YY40 3',5'-cyclic-nucleotide phosphodiesterase n=1 Tax=Lyngbya sp. PCC
           8106 RepID=A0YY40_9CYAN
          Length = 276

 Score =  297 bits (762), Expect = 2e-79,   Method: Composition-based stats.
 Identities = 98/253 (38%), Positives = 147/253 (58%), Gaps = 2/253 (0%)

Query: 9   LAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQD 68
           +     ++++QI+DTHLFA   + ++G+ T +S  AVL+ IR      D+++ TGDL+QD
Sbjct: 1   MPQTEPIQVIQISDTHLFANPDQKMMGLTTADSLIAVLDRIRQLNINPDVLLITGDLSQD 60

Query: 69  QSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLD 128
           ++S +YQ     I  F     W+PGNHD      S L+   IS  K+ F    W+ +LL+
Sbjct: 61  ETSKSYQQLQALIQPFNTSTYWIPGNHDDLSVAESILKKTPIS-IKKAFNISNWKFILLN 119

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           SQ  G  HGEL+   L  L+ +L   PE+ TL+ LHH P+  G  W+D+  LRN+ +L  
Sbjct: 120 SQCPGKVHGELTPESLNDLDSQLQQHPEQPTLIALHHPPVLIGSEWMDKIKLRNSEDLFA 179

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA-PGWRTLE 247
           V+ ++  VK ++ GHIHQE +   NG      PSTCVQFKP     T D +A PG+R L 
Sbjct: 180 VIDRYSQVKLVIFGHIHQEFETIRNGVVYWGCPSTCVQFKPQSVELTFDQVATPGFRVLT 239

Query: 248 LHADGTLTTEVHR 260
           L+++G   +++ R
Sbjct: 240 LYSNGEYNSKIER 252


>UniRef50_D2U2B8 Cyclic 3',5'-adenosine monophosphate phosphodiesterase n=4
           Tax=Gammaproteobacteria RepID=D2U2B8_9ENTR
          Length = 265

 Score =  297 bits (762), Expect = 2e-79,   Method: Composition-based stats.
 Identities = 154/265 (58%), Positives = 192/265 (72%), Gaps = 4/265 (1%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +RILQITDTHLFA   + LLGVNT+ S+ AV++AI       DL+VATGDLAQDQS+ AY
Sbjct: 1   MRILQITDTHLFANADDTLLGVNTFASFHAVIDAILVRNENVDLVVATGDLAQDQSAQAY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
           QHFAEGI    APCVWLPGNHD+QPAM + L  AGI P+K++ I + WQIL+LDSQ+ G 
Sbjct: 61  QHFAEGIKRLSAPCVWLPGNHDYQPAMVATLAKAGILPSKQLLINDNWQILMLDSQIQGA 120

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
            HG+LS+ QL W++       ER  LL+LHHHPLP+GC+WLDQH LRN+  L   L ++ 
Sbjct: 121 VHGKLSKQQLLWMKSCFDAYTERSHLLMLHHHPLPSGCTWLDQHRLRNSHILADYLKQYQ 180

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLEL----HA 250
            +K +LCGHIHQE+D  W G R++ATPSTC+QFKPHC+NFTLDT+ PGWR L+L      
Sbjct: 181 KIKAILCGHIHQEIDEYWQGVRMMATPSTCIQFKPHCTNFTLDTMTPGWRYLDLSINDAG 240

Query: 251 DGTLTTEVHRLADTRFQPDTASEGY 275
           +  L T+V RL   +F PD  S GY
Sbjct: 241 EDVLNTQVCRLDSDKFCPDLDSGGY 265


>UniRef50_A6F721 Icc protein-like protein n=1 Tax=Moritella sp. PE36
           RepID=A6F721_9GAMM
          Length = 274

 Score =  296 bits (759), Expect = 5e-79,   Method: Composition-based stats.
 Identities = 128/261 (49%), Positives = 176/261 (67%), Gaps = 1/261 (0%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + +LQ+TDTHLFA   + LLGV T  SY+ V++AI  +Q  FD ++ATGD++QD + A+Y
Sbjct: 15  INLLQVTDTHLFATAEKDLLGVKTQLSYRHVIDAILQNQQPFDAVLATGDISQDNTPASY 74

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
           Q+FA+ I     PC WLPGNHD  P M  AL+  G+  A +  +   WQI+LLDSQ+ G 
Sbjct: 75  QYFAQHIKRLNKPCYWLPGNHDNIPLMADALRAEGV-LADKYKVVGDWQIVLLDSQLTGS 133

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
           P G L+  QL  L+ +L+  P++  L++LHH+  P GC WLDQH LRNA     +LAK P
Sbjct: 134 PAGYLAPEQLLLLDEQLSAHPDKFALVVLHHNVYPVGCKWLDQHLLRNADAFLAILAKHP 193

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTL 254
              ++L GH+HQ+LD  + G   +A+PSTC QFKPHC  FTLD  APGWR L+LH+DG++
Sbjct: 194 QANHVLFGHVHQQLDKTYAGIHFMASPSTCFQFKPHCDEFTLDARAPGWRYLQLHSDGSI 253

Query: 255 TTEVHRLADTRFQPDTASEGY 275
            ++V RL++  F PD  S+GY
Sbjct: 254 NSQVWRLSNNDFNPDLESKGY 274


>UniRef50_A4B8Z0 Putative uncharacterized protein n=1 Tax=Reinekea blandensis MED297
           RepID=A4B8Z0_9GAMM
          Length = 263

 Score =  294 bits (753), Expect = 2e-78,   Method: Composition-based stats.
 Identities = 104/259 (40%), Positives = 154/259 (59%), Gaps = 2/259 (0%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           ++QITD HL A     LLG+NT  S + +++ +     E DL++ATGD+AQD S  AY++
Sbjct: 7   LVQITDPHLHATSDGTLLGMNTENSLRLIVDRVVNEVPEVDLVIATGDIAQDSSVQAYRN 66

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPH 136
           F E I    AP  W+PGNHD +  M +A     +  A+ V+    W I+LLDS V G  +
Sbjct: 67  FLELIRPISAPMRWIPGNHDSRENMATA--GKDLQHAEPVYELGDWVIILLDSIVPGRVY 124

Query: 137 GELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHV 196
           G L   QLE L++ L    +RH L+  HHHP+P    W+DQ  +RN      ++  + ++
Sbjct: 125 GNLDPDQLELLQKTLDKYQDRHVLIGFHHHPVPMKSRWIDQIGVRNRESFQALVNHYDNI 184

Query: 197 KYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTT 256
           + ++CGH+HQ+ D   NG R ++TPSTCVQF P   +F +D++ P +RTL LH DG L T
Sbjct: 185 RAVVCGHVHQDSDQVINGIRYISTPSTCVQFLPKSQDFGIDSLGPAYRTLTLHPDGQLDT 244

Query: 257 EVHRLADTRFQPDTASEGY 275
            + R+    F+ D + +GY
Sbjct: 245 TISRIDGVDFEIDYSQKGY 263


>UniRef50_Q8YLG0 3',5'-cyclic-nucleotide phosphodiesterase n=3 Tax=Nostocaceae
           RepID=Q8YLG0_ANASP
          Length = 266

 Score =  291 bits (746), Expect = 2e-77,   Method: Composition-based stats.
 Identities = 94/254 (37%), Positives = 147/254 (57%), Gaps = 1/254 (0%)

Query: 9   LAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQD 68
           +  +  + I QITD HL A + + L G++T ES+ AV++ +   + E DL++ TGDL+ D
Sbjct: 1   MNEKLPISIAQITDIHLLASESQRLQGISTTESFLAVMKRLEELRPELDLLLMTGDLSDD 60

Query: 69  QSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLD 128
            +  +Y++    + S +    WLPGNHD   AM   L + G+   ++ F    W  +LL+
Sbjct: 61  GTPESYENLQHYLNSLQIATYWLPGNHDCAIAMDKIL-NLGMVSRRKSFQRGNWNFILLN 119

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           S V    +G LS   L+WL+ +L   P   TL+ LHH PL    +W+D+  L+N+ EL  
Sbjct: 120 SSVTDCVYGYLSATTLDWLDSELKMLPNNPTLIALHHPPLSVNSAWIDRSCLQNSQELFA 179

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLEL 248
           V+ ++P VK +L GHIHQE     +    L +PSTC QF+   + F ++   PG+R L+L
Sbjct: 180 VIDRYPQVKLVLFGHIHQEFRRQRHNVHYLGSPSTCYQFQSQSTTFAINQELPGFRLLKL 239

Query: 249 HADGTLTTEVHRLA 262
           +ADGT TT++ R+ 
Sbjct: 240 YADGTWTTKIERVP 253


>UniRef50_UPI0001698C6A Calcineurin phosphoesterase C-terminal domain protein n=1
           Tax=Endoriftia persephone 'Hot96_1+Hot96_2'
           RepID=UPI0001698C6A
          Length = 279

 Score =  288 bits (738), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 100/264 (37%), Positives = 142/264 (53%), Gaps = 1/264 (0%)

Query: 12  EARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
           +  + +LQ++D+H++A +   L+G+NT +S   V+   R      DL++ATGDL  D S+
Sbjct: 17  DGAITLLQLSDSHIYADQDRCLVGINTQDSLDQVIALARQQLSTPDLLLATGDLVHDASA 76

Query: 72  AAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQV 131
           A YQ  AE +++F  P   LPGNHD    M   L    +           W I+ LDS +
Sbjct: 77  AGYQRIAERLSAFGCPVYCLPGNHDVPKVMQEHLNRPPLYCLPS-LQRGNWSIIFLDSTI 135

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
            G P G L + QLE L   L   P+ HTL+ +HHHP+P G +W+D  +L N   L  +L 
Sbjct: 136 PGKPGGHLDDAQLELLSETLNRHPKHHTLITMHHHPVPVGSAWMDTMALVNPEPLFHLLE 195

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHAD 251
           +   V+ +L GHIHQE D    G RL+ TPSTC+QF      F +D+  PG+R + L   
Sbjct: 196 QHSQVRAVLFGHIHQEFDTKHRGIRLIGTPSTCIQFIAGQDKFGIDSKPPGYRAMVLLES 255

Query: 252 GTLTTEVHRLADTRFQPDTASEGY 275
           G + TEV  L       D +S GY
Sbjct: 256 GEIRTEVRLLQALPLGLDLSSGGY 279


>UniRef50_A4A8X3 Icc protein n=2 Tax=unclassified Gammaproteobacteria
           RepID=A4A8X3_9GAMM
          Length = 278

 Score =  286 bits (733), Expect = 4e-76,   Method: Composition-based stats.
 Identities = 103/265 (38%), Positives = 143/265 (53%), Gaps = 5/265 (1%)

Query: 13  ARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA 72
             VR++Q+TDTHL A     LLG++T  S QAV++ +     + D ++ TGDLA   +  
Sbjct: 16  ETVRVVQLTDTHLKAHDGGKLLGLDTDYSLQAVIDLVNSEYPDPDFVLGTGDLADSGAGD 75

Query: 73  AYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVF 132
           AY               WLPGNHD +  M       G            WQI++LDSQ+ 
Sbjct: 76  AYNRLIGYFDQVSTEHFWLPGNHDLREVMADV---GGARRLPGEIRVGAWQIVMLDSQLP 132

Query: 133 GVPHGELSEFQLEWLERKLADAPER--HTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
           G   G L   +L+ LE  LA + E   +TL+ +HH P+P GC WLD+  + +A     +L
Sbjct: 133 GEVGGHLGRGELQRLEECLAASAEAGLYTLICMHHQPVPVGCDWLDEQMVSDADSFFEIL 192

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHA 250
            ++P V+ +L GH+HQ LD      RLL TPSTCVQF P  ++F +D+ APG+R LEL  
Sbjct: 193 GRYPQVRGVLWGHVHQALDQRCEDLRLLCTPSTCVQFLPKQTDFAVDSRAPGYRWLELEP 252

Query: 251 DGTLTTEVHRLADTRFQPDTASEGY 275
           DGT+ T+V R     F  D  + GY
Sbjct: 253 DGTIRTDVSRAESQIFPVDKEASGY 277


>UniRef50_B7S0L2 Calcineurin-like phosphoesterase C-terminal domain family protein
           n=1 Tax=marine gamma proteobacterium HTCC2148
           RepID=B7S0L2_9GAMM
          Length = 279

 Score =  285 bits (731), Expect = 8e-76,   Method: Composition-based stats.
 Identities = 96/264 (36%), Positives = 142/264 (53%), Gaps = 4/264 (1%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
            VR++QITDTHL A     LL ++T  S + V+E     +   D ++ TGDL+   S  A
Sbjct: 17  TVRLVQITDTHLCANPGGTLLDMDTDRSLKLVIERALQERGTPDGVLCTGDLSDQGSLQA 76

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFG 133
           Y+     +    AP  WLPGNHD    M +A+  +    A+   +   WQ++LL+SQ+ G
Sbjct: 77  YRRLIAHLQEIPAPDFWLPGNHDDLSEMQAAVDTSDRLCAE--VLAGNWQVILLNSQIPG 134

Query: 134 VPHGELSEFQLEWLERKL--ADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
              G L   +LE L   L  A A   H+L+ LHH P+  G +W+DQ  + +A +   ++ 
Sbjct: 135 EVGGRLGSDELEKLRLALERAQAEGLHSLVCLHHQPVAIGSAWIDQQMVEDADQFWEIVD 194

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHAD 251
               VK +L GH+HQ++D       L+A+PS+CVQF P  + F  D   PG+R L+L +D
Sbjct: 195 AASSVKGVLWGHVHQQIDERRGDIALMASPSSCVQFAPGSAMFKADDKPPGYRWLDLCSD 254

Query: 252 GTLTTEVHRLADTRFQPDTASEGY 275
           G++ T V R+    F  D  S GY
Sbjct: 255 GSINTGVSRVTGVDFTVDLESGGY 278


>UniRef50_A0Y9K0 Cyclic AMP phosphodiesterase n=1 Tax=marine gamma proteobacterium
           HTCC2143 RepID=A0Y9K0_9GAMM
          Length = 276

 Score =  283 bits (725), Expect = 4e-75,   Method: Composition-based stats.
 Identities = 108/272 (39%), Positives = 159/272 (58%), Gaps = 3/272 (1%)

Query: 5   LTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGD 64
           L +P+     +++LQITDTHL AQ  E LLG+NT  S + V++ +R  +   DL++ATGD
Sbjct: 7   LLVPIDSHQPIKLLQITDTHLGAQAAETLLGLNTDYSLEQVVDLVRRERPHADLLLATGD 66

Query: 65  LAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQI 124
           ++   +  +Y  + +         +WLPGNHD   AM  A    G   A    IG  W I
Sbjct: 67  ISSCGAGQSYHRYRQLTKGIADQTLWLPGNHDTVAAMREA-AKDGNEMAGCATIG-NWHI 124

Query: 125 LLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAG 184
           ++L+S+  G   G LS+ +L  L   L  + E + L+ LHHHP+  GC WLD+  + NA 
Sbjct: 125 IMLNSKTPGKVGGSLSDKELAKLRVGLQQSREGYALVCLHHHPVSIGCDWLDEQKVSNAE 184

Query: 185 ELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWR 244
            L +VL +F HV+ LL GH+HQ++D   NG +L+ATPSTC+QF    ++F LD ++PG+R
Sbjct: 185 TLFSVLDEFTHVRGLLWGHVHQQIDQQRNGVKLMATPSTCIQFAADSADFKLDRLSPGYR 244

Query: 245 TLELHADGTLTTEVHRLADTRFQPDT-ASEGY 275
            L+L  +G + T V R++   F  D   S GY
Sbjct: 245 WLDLQENGDIETGVSRVSGVVFDIDYDDSSGY 276


>UniRef50_Q12J78 Metallophosphoesterase n=21 Tax=Shewanella RepID=Q12J78_SHEDO
          Length = 279

 Score =  283 bits (724), Expect = 5e-75,   Method: Composition-based stats.
 Identities = 116/275 (42%), Positives = 169/275 (61%), Gaps = 5/275 (1%)

Query: 5   LTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGD 64
           ++  +     VR++Q+TD HLFA     LLGV T++S+ AVL  I    H   L++ATGD
Sbjct: 6   VSYSITESDTVRLVQVTDPHLFADLEAQLLGVTTYQSFSAVLAMINQANHGQHLLLATGD 65

Query: 65  LAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQI 124
           L+QD S  +YQ FA  +     PC +LPGNHD    M  ++Q   +   +R+ IG QWQI
Sbjct: 66  LSQDYSPESYQLFANTVKRVPVPCHYLPGNHDDARLMNLSVQGDHVFGQQRIIIG-QWQI 124

Query: 125 LLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAG 184
           L+L+S + G P G L+  Q   +++ +A AP++H LL +HH+P+   C+WLDQH + N  
Sbjct: 125 LMLNSTLIGKPGGYLAPSQFTLIKQAIAQAPDKHVLLAMHHNPVLVDCAWLDQHCMANGE 184

Query: 185 ELDTVLAKFPHVKYLLCGHIHQELDLDWNG----RRLLATPSTCVQFKPHCSNFTLDTIA 240
           EL     +F  +K L+ GH+HQ LD    G     +L+ATPSTC+QFKP  ++F LD + 
Sbjct: 185 ELIDFAGQFKQIKGLVWGHVHQALDRQVLGQFGPIKLMATPSTCIQFKPKSAHFALDGLQ 244

Query: 241 PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY 275
           PG+R L+L +DG++ T+V+RLA   F  D  + GY
Sbjct: 245 PGYRLLDLASDGSIHTQVYRLAGDEFSADNHANGY 279


>UniRef50_Q21NU3 Metallophosphoesterase n=3 Tax=Gammaproteobacteria
           RepID=Q21NU3_SACD2
          Length = 271

 Score =  281 bits (719), Expect = 2e-74,   Method: Composition-based stats.
 Identities = 108/264 (40%), Positives = 153/264 (57%), Gaps = 7/264 (2%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
            +R++QITD HL +Q  E +LG++T +S   VLE I+  +   DLI+ATGD++ D  +A+
Sbjct: 13  PLRVVQITDCHLGSQPGELMLGLDTDQSLFDVLELIQNSEPTPDLILATGDISNDGGAAS 72

Query: 74  YQHFAEGIASF--RAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQV 131
           YQ F + +  +       WLPGNHD    M        I P +  +  + W ++LLDS++
Sbjct: 73  YQRFIDIVNHYFPGVALAWLPGNHDDPLNMDQV----DILPIEAHYRAQGWNLILLDSRI 128

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
                GEL   +L  L+ +L    E  T++ LHH P+P G  W+DQ+ ++NA     VL 
Sbjct: 129 PMEEGGELHPNELMRLDAELKANSE-PTMVFLHHQPVPVGSEWIDQYVVKNAEAFFDVLD 187

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHAD 251
           K+ HVK +  GH+HQE     N   LLATPSTCVQF P    F LDTI PG+R+  L+AD
Sbjct: 188 KYDHVKAVSWGHVHQEFQDSRNNVTLLATPSTCVQFAPKSKPFKLDTIMPGYRSYSLNAD 247

Query: 252 GTLTTEVHRLADTRFQPDTASEGY 275
           G+ T+EV R+    +  D AS GY
Sbjct: 248 GSFTSEVKRIQTKAYAIDFASTGY 271


>UniRef50_C5SEA9 Calcineurin phosphoesterase domain protein n=1 Tax=Allochromatium
           vinosum DSM 180 RepID=C5SEA9_CHRVI
          Length = 261

 Score =  280 bits (716), Expect = 4e-74,   Method: Composition-based stats.
 Identities = 95/262 (36%), Positives = 135/262 (51%), Gaps = 2/262 (0%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
            +R+LQ+TD HLF      LLG+ T  S+++VL          D ++ TGDL  D++   
Sbjct: 2   PLRLLQLTDPHLFGDPGGQLLGITTRRSFESVLALALSESPAPDALILTGDLVHDETPVG 61

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFG 133
           Y++  E +     P   + GNHD Q  M   L  A +  +  +   + W ++ LDS   G
Sbjct: 62  YRYLRERLNRTGIPYYCIGGNHDIQSLMMEQLGPAAL-VSVALRRLDGWNLIFLDSSEPG 120

Query: 134 VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKF 193
              G L+E QL  L   LAD      L+ LHHHP   G +W+D+  + N   L  +  + 
Sbjct: 121 SDGGRLTETQLTQLTDLLAD-ERAPALICLHHHPAAVGSAWIDRIGVANGASLLDLCNRH 179

Query: 194 PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGT 253
           PHVK +L GH+HQE        RLL  P+TC QF+P   +F +D I PG+R L L+ DG 
Sbjct: 180 PHVKAVLFGHVHQEFSAWHGDCRLLGAPATCFQFEPRSRDFAIDEIPPGYRELMLYPDGR 239

Query: 254 LTTEVHRLADTRFQPDTASEGY 275
           LTT V RL +   +P   + GY
Sbjct: 240 LTTRVVRLVEYAERPLYQAGGY 261


>UniRef50_B8GLR4 Icc protein n=1 Tax=Thioalkalivibrio sp. HL-EbGR7
           RepID=B8GLR4_THISH
          Length = 266

 Score =  279 bits (715), Expect = 6e-74,   Method: Composition-based stats.
 Identities = 94/256 (36%), Positives = 135/256 (52%), Gaps = 1/256 (0%)

Query: 9   LAGEARVRILQITDTHLFAQKHEALLG-VNTWESYQAVLEAIRPHQHEFDLIVATGDLAQ 67
           ++    + ++QITD HL A         ++T  +   VL  IR    + DL++ATGDLA+
Sbjct: 1   MSRSRPLTVVQITDPHLGAPSEGMYGVTIDTGATLARVLADIRARCPQADLMLATGDLAE 60

Query: 68  DQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLL 127
               A Y    + ++    P   LPGNHD    M  AL DA      RV   E W +++L
Sbjct: 61  RPVPATYAQLRKALSGLPMPVHCLPGNHDEPQVMEEALADAPGIDCARVITREDWVVVML 120

Query: 128 DSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELD 187
           DS + G   G L   +LE+LE  L+  P R+ L+ LHH  +  G  W+D+  L +AG L 
Sbjct: 121 DSTIPGHAGGALDADELEFLEETLSRHPARNALICLHHPVVAVGSRWMDRMKLADAGALF 180

Query: 188 TVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLE 247
            +  +   V+ LL GHIHQ+ +    G RL+ TPSTC+QF P   +F LD + P WR L 
Sbjct: 181 QITDRHTQVRGLLFGHIHQDFEAVRKGVRLIGTPSTCLQFLPESDDFALDALPPAWRHLT 240

Query: 248 LHADGTLTTEVHRLAD 263
           LH DG + T+V  + +
Sbjct: 241 LHPDGRIDTQVIYVDE 256


>UniRef50_C7R6J1 Metallophosphoesterase n=1 Tax=Kangiella koreensis DSM 16069
           RepID=C7R6J1_KANKD
          Length = 274

 Score =  278 bits (711), Expect = 1e-73,   Method: Composition-based stats.
 Identities = 97/275 (35%), Positives = 148/275 (53%), Gaps = 1/275 (0%)

Query: 1   MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV 60
           M +       G   + +L ++D HLFA    +LLGVNT ES+ AVLE IR    + D+I+
Sbjct: 1   MTNDCKRLFIGRPEMTVLHLSDPHLFADDQGSLLGVNTQESFCAVLEDIRARAIDPDVII 60

Query: 61  ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE 120
            TGD++QD S  +YQ FA+ +A F  P   L GNHD    + S L +A +   K++   +
Sbjct: 61  VTGDISQDYSKDSYQFFAKQMAKFGKPVFTLAGNHDEVEYLTSFLSEAPLFNHKQILT-D 119

Query: 121 QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL 180
            WQIL++ S +    HG +   +L+W  R L +  +  T++ +HHHP+P G  WLD+  +
Sbjct: 120 HWQILMISSHIEDEVHGRIDPSELKWARRCLEENSDLPTMIYMHHHPVPVGSDWLDEIGV 179

Query: 181 RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA 240
            N  EL  ++ + P VK    GH+HQ  +   +     + PSTCVQFK H ++F      
Sbjct: 180 SNKDELLELVTEHPQVKLCGFGHVHQFSEYKIDNAVYCSVPSTCVQFKRHSADFAASGET 239

Query: 241 PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY 275
           PG+   + HADG +  + +R+       + A  GY
Sbjct: 240 PGYAVYQCHADGVIDKQNYRVDHYLPSVNFAISGY 274


>UniRef50_Q606D3 Cyclic AMP phosphodiesterase n=1 Tax=Methylococcus capsulatus
           RepID=Q606D3_METCA
          Length = 259

 Score =  274 bits (702), Expect = 2e-72,   Method: Composition-based stats.
 Identities = 102/254 (40%), Positives = 144/254 (56%), Gaps = 3/254 (1%)

Query: 9   LAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQD 68
           +     + +LQ+TD+H+         G ++  S  AV++    +Q  FDL++ TGDLAQ+
Sbjct: 1   MPDSGTLCLLQLTDSHILPDAESRFYGSDSAASLGAVIDH--ANQRRFDLVLFTGDLAQE 58

Query: 69  QSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLD 128
               +Y+  A   A+  APC WLPGNHD        L+   +   + V    +W I+ LD
Sbjct: 59  PVPQSYRRLAGICAALPAPCHWLPGNHDEPALARHVLESTPL-LHQPVIRRGRWLIVCLD 117

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           S V G   G LS  Q + LER L+  P  HTL+ LHHHP+P+G +W+D   L NAGE   
Sbjct: 118 STVPGSAGGSLSTGQFDLLERTLSRHPSLHTLVALHHHPVPSGSAWMDTMILDNAGEFFA 177

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLEL 248
           VL + P VK ++ GH HQ  D++  G R+L TPSTC+QF+P    F LD   PG+R LEL
Sbjct: 178 VLRRHPQVKAVVHGHTHQVADVEIEGTRVLGTPSTCIQFRPASQTFALDAERPGYRWLEL 237

Query: 249 HADGTLTTEVHRLA 262
             DG++ T + R+A
Sbjct: 238 GPDGSVATGICRVA 251


>UniRef50_A3M1D0 Cyclic 3'5'-adenosine monophosphate phosphodiesterase n=17
           Tax=Acinetobacter RepID=A3M1D0_ACIBT
          Length = 270

 Score =  273 bits (698), Expect = 5e-72,   Method: Composition-based stats.
 Identities = 93/259 (35%), Positives = 134/259 (51%), Gaps = 3/259 (1%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           I+QITDTHL        +G+N  ES+ A+++ I     E D I+ TGDLAQ  +   Y+ 
Sbjct: 15  IIQITDTHLLEYPQLEFVGMNPEESFHAIIQQILKQHPEADAIIHTGDLAQAPTPITYKR 74

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPH 136
           +   + +   P     GNHD         ++        V     W++++L+S V G   
Sbjct: 75  YINFMQTLGLPFFQTLGNHDNVDHFPLHNENH---QQPVVVGLGNWRVIMLNSAVKGKVD 131

Query: 137 GELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHV 196
           G LS  QLE L   L    +   LL  HHHP      W+D H L+N+  L   L+ F +V
Sbjct: 132 GHLSSEQLENLANLLEQFADHPVLLACHHHPFAMKSKWIDHHKLQNSNALLDTLSPFQNV 191

Query: 197 KYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTT 256
           K L+CGH+HQ+    W G    +TPST VQFKP  ++F LD  APG+R + L+ DG+  T
Sbjct: 192 KALVCGHVHQDSLNIWQGIEFFSTPSTSVQFKPFSNDFALDQNAPGYRYIRLNNDGSFET 251

Query: 257 EVHRLADTRFQPDTASEGY 275
           +V RL + + + +T   GY
Sbjct: 252 KVFRLENFKTRINTDISGY 270


>UniRef50_Q3JEM1 Metallophosphoesterase n=2 Tax=Nitrosococcus oceani
           RepID=Q3JEM1_NITOC
          Length = 270

 Score =  269 bits (688), Expect = 7e-71,   Method: Composition-based stats.
 Identities = 97/265 (36%), Positives = 137/265 (51%), Gaps = 4/265 (1%)

Query: 1   MESLLTLPLAGEAR--VRILQITDTHLFAQKHEALL-GVNTWESYQAVLEAIRPHQHEFD 57
           M SL  L +A +    + +LQ+TD+HL A     L   +NT  S  AVL  I+      D
Sbjct: 1   MTSLPHLKIANDRSEFINVLQLTDSHLLADSEAFLWNDLNTRRSLVAVLNHIQQQGLLGD 60

Query: 58  LIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVF 117
           L+V +GD+A+     AY    E       P   LPGNHD    M   L    +S  + + 
Sbjct: 61  LMVISGDIAEKAEPEAYYWLLERCQELGLPVYCLPGNHDDPVLMDEILNGMNVS-TESLV 119

Query: 118 IGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQ 177
             + WQ++ L+S V    HG LS+ QL +L R LAD+ + +TL+ LHH P+  G  W+D 
Sbjct: 120 TLKNWQLIFLNSVVTQRSHGHLSKGQLGFLNRSLADSLDLNTLIFLHHPPVALGSPWMDA 179

Query: 178 HSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLD 237
             + NA +   VL  +P V+ +  GH HQE   +  G +LL +PSTCVQF P   +F LD
Sbjct: 180 MGVDNAADFFAVLDLYPQVRGVAWGHAHQEFHTERQGVQLLGSPSTCVQFVPGSEHFQLD 239

Query: 238 TIAPGWRTLELHADGTLTTEVHRLA 262
              PG+R L L   G + T V+ + 
Sbjct: 240 QRGPGYRWLILLPGGQIETRVYYVD 264


>UniRef50_B5JTJ8 Metallophosphoesterase n=1 Tax=gamma proteobacterium HTCC5015
           RepID=B5JTJ8_9GAMM
          Length = 250

 Score =  268 bits (686), Expect = 1e-70,   Method: Composition-based stats.
 Identities = 85/248 (34%), Positives = 126/248 (50%), Gaps = 2/248 (0%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           R+LQ++D H+ A     L G +T E  + +LE I+     F  ++ +GDL+   S+ +YQ
Sbjct: 5   RLLQLSDCHITADADTQLRGYDTHELLRKLLEQIKKRDRHFHALLLSGDLSDRGSAESYQ 64

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVP 135
                ++  + P   LPGNHD    M   L+   I+          W++L+L+SQ  G  
Sbjct: 65  RLNALLSFCKKPIYALPGNHDQLLEMRDQLRK--IAQCVHSADLGTWRLLMLNSQQAGKT 122

Query: 136 HGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPH 195
            G LSE +L  L+  L       +L+ +HH P     +W+D  +L+N  EL  ++     
Sbjct: 123 EGYLSEDELSRLKLWLDHGKNIPSLVAVHHPPCSIHSAWMDAINLQNGDELLDIVKSHHQ 182

Query: 196 VKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLT 255
           VK +  GH+HQ  D   +G RLL TPSTC QF P    F +D   PG+R  ELH +G   
Sbjct: 183 VKAISFGHVHQAFDQTIHGVRLLGTPSTCFQFTPERDEFDIDDKPPGYRWFELHDNGEFD 242

Query: 256 TEVHRLAD 263
           T+V  L D
Sbjct: 243 TDVTWLGD 250


>UniRef50_Q2JPZ0 Icc protein n=2 Tax=Synechococcus RepID=Q2JPZ0_SYNJB
          Length = 264

 Score =  265 bits (678), Expect = 1e-69,   Method: Composition-based stats.
 Identities = 101/261 (38%), Positives = 142/261 (54%), Gaps = 3/261 (1%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           ++QI+D HLFA+ H  LLGV+T  S+  V +AI       DL++ TGDL+QD S+A+Y  
Sbjct: 5   VVQISDLHLFAKPHHRLLGVDTEASFLQVQKAIAALDPLPDLLLLTGDLSQDGSAASYAR 64

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPH 136
               + +      WL GNHD    M   L    +    + F  E W  +LL+S V G   
Sbjct: 65  LRAHLQALPIDTYWLAGNHDRLHTMNQELHAERLF-GDKSFSRENWSFILLNSLVPGKDS 123

Query: 137 GELSEFQLEWLERKL--ADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
           G L+E  L WL ++L  + A + H LL LHH P     +WLDQ +L+    L  VL +F 
Sbjct: 124 GYLTERTLLWLRQELQRSKAAQHHVLLALHHPPFSVDSAWLDQSALQQPERLFGVLDEFD 183

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTL 254
           H++ ++ GHIHQ+L     G   LA PSTCVQF+P    F L+ I P  R + L  DG+ 
Sbjct: 184 HIRLVVFGHIHQDLHRRREGVDYLACPSTCVQFRPKSPQFGLEVIPPALRQIWLERDGSF 243

Query: 255 TTEVHRLADTRFQPDTASEGY 275
            T+V R+     +P+ A +GY
Sbjct: 244 KTQVQRVGAALQRPNLALKGY 264


>UniRef50_B8KUM1 Cyclic AMP phosphodiesterase n=1 Tax=gamma proteobacterium NOR51-B
           RepID=B8KUM1_9GAMM
          Length = 277

 Score =  262 bits (669), Expect = 1e-68,   Method: Composition-based stats.
 Identities = 103/265 (38%), Positives = 145/265 (54%), Gaps = 7/265 (2%)

Query: 13  ARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA 72
           A +++LQITDTHL  Q+   LL V+T  S  AV+ A+       D ++ TGD+A   +  
Sbjct: 17  ATLKLLQITDTHLMQQRGGRLLNVDTDASLSAVV-ALASQSLPADALLITGDIAGAGAGD 75

Query: 73  AYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVF 132
           AY    E ++  +AP  WLPGNHD   A    L        KR  I   WQ+L+LDSQV 
Sbjct: 76  AYYRLEEALSPLQAPSFWLPGNHDDGHACADELS----WHFKRQVIFPHWQVLMLDSQVR 131

Query: 133 GVPHGELSEFQLEWLERKLAD--APERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
           G   G L++ +L+ L   +++  A  RH L+ LHH   P GC WLD   + NA ++   L
Sbjct: 132 GEVGGILAQAELDALVTAVSESNASGRHLLVALHHPLWPLGCDWLDSQRVANADDVAACL 191

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHA 250
               +   ++ GH+HQE D    G R L TPSTC+QF  +  +F +D   PG+R L+L A
Sbjct: 192 EMAENKVVVISGHVHQESDAIHRGARYLTTPSTCIQFAKYSPDFKVDDSGPGYRWLDLQA 251

Query: 251 DGTLTTEVHRLADTRFQPDTASEGY 275
           DG ++T V R+ +  F  D  S+GY
Sbjct: 252 DGFVSTGVERVTEVSFPVDLDSDGY 276


>UniRef50_Q2KTW6 cAMP phosphodiesterase n=5 Tax=Bordetella RepID=Q2KTW6_BORA1
          Length = 270

 Score =  260 bits (666), Expect = 3e-68,   Method: Composition-based stats.
 Identities = 99/261 (37%), Positives = 140/261 (53%), Gaps = 7/261 (2%)

Query: 4   LLTLPLAG-EARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVAT 62
           +   PLA  +A   +LQ++D+HL A     +LGVNT  S +AV++  R  + + +L++ T
Sbjct: 1   MPEHPLAAHDAPALLLQLSDSHLMADPDARMLGVNTDASLRAVIDLARRQEGQPELMLLT 60

Query: 63  GDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQW 122
           GDLAQD S  AY+     +    AP   LPGNHD    M   L D        V+    W
Sbjct: 61  GDLAQDGSPQAYRRLQAHLR--GAPVRCLPGNHDAPEVMRQILADW----ISPVYDLPGW 114

Query: 123 QILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRN 182
           +I++LDS V G   G L E QL  L++ + DA  RH L+ LHH+      +W D   + N
Sbjct: 115 RIIMLDSTVPGEDFGHLDEAQLAVLDQAIKDAGPRHVLVALHHNLARVDGNWQDPMMVDN 174

Query: 183 AGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPG 242
           A  +   L+  P  +  L GHIHQE D   +  RLL TPSTC QF  +     +D  APG
Sbjct: 175 AAAVFARLSAHPQTRIALWGHIHQEFDCRHHHLRLLGTPSTCFQFTLNNGQHAIDAKAPG 234

Query: 243 WRTLELHADGTLTTEVHRLAD 263
           +R ++L+ADG++ T + RL  
Sbjct: 235 YRWIKLYADGSIATGIRRLDA 255


>UniRef50_A0Z341 Metallophosphoesterase n=1 Tax=marine gamma proteobacterium
           HTCC2080 RepID=A0Z341_9GAMM
          Length = 275

 Score =  260 bits (664), Expect = 4e-68,   Method: Composition-based stats.
 Identities = 92/269 (34%), Positives = 132/269 (49%), Gaps = 7/269 (2%)

Query: 9   LAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQD 68
           L     + ++Q+TD HL   +   LL V+T +S  AVLE +       D ++ TGD+A D
Sbjct: 11  LNNGDTLTLVQVTDAHLMGVRGGRLLNVDTDDSLAAVLELVEARPEPPDALLITGDIAGD 70

Query: 69  QSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLD 128
            +  AYQ FA+ + +  AP  WLPGNHD                  R      W +++LD
Sbjct: 71  GAGDAYQRFAQALEAIPAPSFWLPGNHDDCDE-----SVVDRERFIRTVTNPHWLVVMLD 125

Query: 129 SQVFGVPHGELSEFQLEWLERKLADA--PERHTLLLLHHHPLPAGCSWLDQHSLRNAGEL 186
           SQ      G L+  +L+ L + +  A    +H L+ LHH   P GC WLD   + N+   
Sbjct: 126 SQQTDEVGGYLAANELDALSQAVDRANQEGKHLLVALHHPLQPVGCDWLDPQRVANSSAF 185

Query: 187 DTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTL 246
           +  + +  +   ++ GH+HQE D      R L TPSTC+QF P+  NF +   APG+R L
Sbjct: 186 ELEVQRCRNQVVVIAGHVHQESDQVSGNIRYLTTPSTCIQFAPNQVNFKVGDQAPGYRWL 245

Query: 247 ELHADGTLTTEVHRLADTRFQPDTASEGY 275
            L   G + T V R+ D  F  D  S GY
Sbjct: 246 RLAPSGEIETGVERVTDREFPVDLDSGGY 274


>UniRef50_B9ZKN4 Calcineurin phosphoesterase domain protein n=1 Tax=Thioalkalivibrio
           sp. K90mix RepID=B9ZKN4_9GAMM
          Length = 265

 Score =  258 bits (659), Expect = 2e-67,   Method: Composition-based stats.
 Identities = 88/252 (34%), Positives = 131/252 (51%), Gaps = 4/252 (1%)

Query: 16  RILQITDTHLFAQKHEALLGV-NTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           R++QI+DTHL         G  ++    + +L A+ P +   D ++ +GDLA+D   A Y
Sbjct: 9   RLIQISDTHLGRVPGPIRAGYPDSDTQLERILGAL-PREPAADALLLSGDLAEDPEPATY 67

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
              A  + S R P + L GNHD    + +AL+           +G  W+++ LDS   G 
Sbjct: 68  ARLARLLGSRREPMLALAGNHDDCQTLRTALEPETCQVHGERMLGP-WKLIGLDSSTPGE 126

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
             G L   + E LE+ L+  P+R T++ LHH P+  G +W+D+  L +   L  VL + P
Sbjct: 127 AAGRLDASECERLEKSLSADPDRPTVVALHHPPVAIGSAWMDRLGLLDPDALFAVLDRHP 186

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLD-TIAPGWRTLELHADGT 253
            V+  L GHIHQ+         LL +PSTCVQF P    F +D  +  G+R L+LH DG 
Sbjct: 187 QVRACLFGHIHQDFRARRGAIELLGSPSTCVQFTPGSEEFAVDAALDAGYRILDLHPDGR 246

Query: 254 LTTEVHRLADTR 265
             T+V R+  TR
Sbjct: 247 FDTQVVRVPGTR 258


>UniRef50_Q1YUP4 CAMP phosphodiesterase n=1 Tax=gamma proteobacterium HTCC2207
           RepID=Q1YUP4_9GAMM
          Length = 261

 Score =  258 bits (659), Expect = 2e-67,   Method: Composition-based stats.
 Identities = 101/263 (38%), Positives = 138/263 (52%), Gaps = 3/263 (1%)

Query: 13  ARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA 72
           + V I QITD HL A + E L GV T+ES+ A L+A         L++ TGDLA D  + 
Sbjct: 2   STVHITQITDLHLGADEQETLGGVTTFESFNAALQASEDQGRADSLLLLTGDLASDYQAG 61

Query: 73  AYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVF 132
           AYQ   + +       +WLPGNHD    M + L      P  R++    W ILLLDS   
Sbjct: 62  AYQLLNKVLTEKHRQALWLPGNHDHLETMEANLTA---FPRVRIYEAGAWGILLLDSSKA 118

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
           G P G  SE +L++ E+ L     +  L+ +HH P+    +WLDQ  + N   L  +L  
Sbjct: 119 GQPGGHFSEAELQFAEQGLKHLAGKFVLVAVHHSPVRVNSAWLDQQQIDNHHRLYDLLVA 178

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADG 252
              VK ++ GH+HQ  D  W    + +TPS+CVQF+ H  +F L    PG+R L+LH DG
Sbjct: 179 HGQVKAVVTGHVHQHHDSLWGDLPVYSTPSSCVQFEQHSHDFGLADKPPGYRWLDLHDDG 238

Query: 253 TLTTEVHRLADTRFQPDTASEGY 275
           +L T V  L D   Q D +  GY
Sbjct: 239 SLDTGVEFLKDFAQQCDRSCAGY 261


>UniRef50_B1XQ99 Putative 3',5'-cyclic-nucleotide phosphodiesterase n=1
           Tax=Synechococcus sp. PCC 7002 RepID=B1XQ99_SYNP2
          Length = 255

 Score =  252 bits (644), Expect = 1e-65,   Method: Composition-based stats.
 Identities = 91/254 (35%), Positives = 124/254 (48%), Gaps = 9/254 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           V I QITDTHL       + GV T  S+QAVL A++  + +   ++ TGDLA    + +Y
Sbjct: 2   VLIAQITDTHLLDHPEAEMRGVKTDASFQAVLAAVQQFKPDR--LILTGDLAHHGEAISY 59

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDS--QVF 132
           +   + + + + P  WLPGNHD    M   LQ   +SP K V +G  W++LLLDS  +  
Sbjct: 60  ERLRDLVEATQIPSYWLPGNHDDPELMAGILQGDYLSPDKNVALG-NWKLLLLDSFLENP 118

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
               G L   QL WL  +L         + +HHH +PAG  WLDQ  + N  E   ++  
Sbjct: 119 EYGEGFLDTAQLAWLAERLEHHQNSPVAIAIHHHVVPAGVDWLDQIDMTNRAEFWQIVQH 178

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTI----APGWRTLEL 248
            P VK +  GH+H E  +   G     TPSTC Q  P               PG+R  EL
Sbjct: 179 HPQVKTVFFGHVHLEYSVTQGGIPCFGTPSTCTQVTPPDQEPIEGDRQLWEQPGFRLFEL 238

Query: 249 HADGTLTTEVHRLA 262
           H DG   T+V R+ 
Sbjct: 239 HDDGRFQTKVQRIP 252


>UniRef50_Q0EZ19 Ser/Thr protein phosphatase n=1 Tax=Mariprofundus ferrooxydans PV-1
           RepID=Q0EZ19_9PROT
          Length = 265

 Score =  250 bits (638), Expect = 5e-65,   Method: Composition-based stats.
 Identities = 95/259 (36%), Positives = 138/259 (53%), Gaps = 3/259 (1%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
            +++L I+D+HL++     L G+   +S+ AVL          D ++  GD+AQD+    
Sbjct: 2   SLQLLHISDSHLYSDPASLLKGIRPHDSFTAVLADAYRSFPVVDAVILGGDMAQDEQPET 61

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV--FIGEQWQILLLDSQV 131
           Y      +  ++AP +  PGNH     +   L  A  +        +  +WQI+ L+S  
Sbjct: 62  YHRLVSMLPDWQAPMMLTPGNHAALGYLSGTLIPALRARGAYSDRLLSGRWQIITLNSHH 121

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
            G   G L   +LE L++ L+ +   HTL+ LHHHP+P G  WLD+  L N   L  ++ 
Sbjct: 122 PGHISGLLPASELERLQQLLSVSAGIHTLIALHHHPIPIGSRWLDEIDLVNRDALWEIVH 181

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHAD 251
           K  HV+ LLCGHIHQ  D   +G R+L +PSTCVQF P   NF L  I+PG+R LEL  D
Sbjct: 182 KHSHVRALLCGHIHQSFDTIHDGVRVLGSPSTCVQFTPGTDNFALADISPGYRWLELLDD 241

Query: 252 GTLTTEVHRLADTRFQPDT 270
           G ++T VHR+      PD 
Sbjct: 242 GNISTTVHRITGFI-PPDL 259


>UniRef50_Q0AC05 Metallophosphoesterase n=1 Tax=Alkalilimnicola ehrlichii MLHE-1
           RepID=Q0AC05_ALHEH
          Length = 251

 Score =  243 bits (621), Expect = 4e-63,   Method: Composition-based stats.
 Identities = 91/247 (36%), Positives = 125/247 (50%), Gaps = 4/247 (1%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           R++QITD HL A   + + G++ W S  AVL AI       DL++ +GDL QD       
Sbjct: 5   RLVQITDCHLSAAPGKRVRGMDPWRSLDAVLAAI-GRGPRPDLLLVSGDLTQDLGKPVLA 63

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVP 135
              E +       + LPGNHD   A+      + +          +WQ+LL+D+   G  
Sbjct: 64  RLRERLVPLADRVLALPGNHDDPEALARVFPGSPVDTGATSHSLGEWQLLLMDTSRPGRV 123

Query: 136 HGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPH 195
            GE+   +LE LE  L    E   L   HH PL  G +WLD   L +   L   L + P 
Sbjct: 124 EGEMGVQRLEALEFLL---HEGPALCAGHHPPLACGSAWLDAIGLEDGATLLAWLKRHPQ 180

Query: 196 VKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLT 255
           V+ +L GHIHQ LD      RLL TP+T  QF+P  + F LDT  PG+RT++L  +G LT
Sbjct: 181 VRGMLFGHIHQALDRRQGALRLLGTPATSFQFRPGRARFALDTRLPGYRTVKLWPNGRLT 240

Query: 256 TEVHRLA 262
           + V R+A
Sbjct: 241 SRVSRVA 247


>UniRef50_C8PWU2 Calcineurin phosphoesterase domain protein n=1 Tax=Enhydrobacter
           aerosaccus SK60 RepID=C8PWU2_9GAMM
          Length = 275

 Score =  243 bits (621), Expect = 5e-63,   Method: Composition-based stats.
 Identities = 82/255 (32%), Positives = 132/255 (51%), Gaps = 12/255 (4%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           I++++D HLF   ++ + GVNT +++++VL  +R  + + DL+V TGDL  + +   Y  
Sbjct: 18  IIELSDLHLFDDPNKLMNGVNTADTFESVLSLVRQQRDDVDLLVLTGDLCHEPTPQNYDR 77

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGIS----------PAKRVFIGEQWQILL 126
               +     P + +PGNHD    + + L  A                     + W +LL
Sbjct: 78  LFATLDDVNIPFIAIPGNHDVTLELDNHLPFAQRRHLPVKSDSRLQNCYSIATDYWDLLL 137

Query: 127 LDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGEL 186
           LDS   G  HG++ E  L WL ++LA+A  R   +  HH  +    +WLD+++L NA   
Sbjct: 138 LDSSCEGHSHGKIDEQSLLWLAQQLANA-NRPCAIFCHHPMVLIDSTWLDEYTLINADRF 196

Query: 187 DTVLAKF-PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRT 245
             V+  +   +K +  GHIHQE+     G  +   PST +QFKP C ++T+D IAPG R 
Sbjct: 197 WEVVMPYLDRIKAIFVGHIHQEMHKITYGISVFGCPSTSLQFKPLCKDYTIDEIAPGLRW 256

Query: 246 LELHADGTLTTEVHR 260
           + L+ +G L T + R
Sbjct: 257 INLYNNGLLATGIKR 271


>UniRef50_Q1QUF7 Metallophosphoesterase n=1 Tax=Chromohalobacter salexigens DSM 3043
           RepID=Q1QUF7_CHRSD
          Length = 244

 Score =  239 bits (610), Expect = 9e-62,   Method: Composition-based stats.
 Identities = 83/254 (32%), Positives = 127/254 (50%), Gaps = 15/254 (5%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +R++QI+D HL A               +AV+   R  + +   ++ TGD++QD+S AAY
Sbjct: 1   MRLVQISDCHLCANPEARSRIGYPLHQLRAVVARARQLRPDI--VLVTGDISQDESPAAY 58

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
           +H  E  ++F  P  W+ GNHD    M        + P        +W++LLLDS+V G 
Sbjct: 59  RHAYEVFSAFECPWFWMTGNHDHPEFMAE------LHPFHDELDLGEWRLLLLDSRVPGQ 112

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
             GEL +  L+ L  +L +  +R TLL +HH PL  G +W+D   L +   L   LA + 
Sbjct: 113 AAGELGQGPLQDLAARLEED-DRPTLLAMHHPPLEIGSAWMDALGLADREALWQTLAAYG 171

Query: 195 HVKYLLCGHIHQELDLDW----NGRRLLATPSTCVQFKPHCSNFTLDTI-APGWRTLELH 249
            V+ +LCGHIHQ              +   P+T  QF P  ++F LD    PG+R ++L 
Sbjct: 172 QVRAILCGHIHQAFAARHASSQGEIAVYGCPATADQFLPRQADFALDEASRPGFRVIDLE 231

Query: 250 ADGTLTTEVHRLAD 263
            +  L+T V R+  
Sbjct: 232 GE-RLSTWVERVDP 244


>UniRef50_A8ZM80 Phosphodiesterase, putative n=1 Tax=Acaryochloris marina MBIC11017
           RepID=A8ZM80_ACAM1
          Length = 259

 Score =  236 bits (603), Expect = 6e-61,   Method: Composition-based stats.
 Identities = 96/258 (37%), Positives = 130/258 (50%), Gaps = 13/258 (5%)

Query: 13  ARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA 72
           A + + QI+DTHL A     L G N W+S QAVL+ +   Q +   I+ TGDLA   S  
Sbjct: 3   APITLAQISDTHLLADTTALLRGTNPWQSLQAVLQQVNRDQLDG--ILLTGDLADQGSVV 60

Query: 73  AYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVF 132
           AYQH    I   + P  WLPGNHD   AM+  LQ   +   + + +G  W ++ L+S + 
Sbjct: 61  AYQHLMRAILPLKMPAYWLPGNHDQVEAMHRELQSPQLYGPQAIHLGS-WLLISLNSVLP 119

Query: 133 GV--PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
                 G LS   L+ L+  L   P + T++ LHHHP+  G  WLDQ  ++NA  L T+L
Sbjct: 120 SAQFGEGYLSVSALQQLQSVLTQHPHKPTVIALHHHPVAIGIDWLDQMQVQNADALLTLL 179

Query: 191 AKFPHVKYLLCGHIHQELDLDW------NGRRLLATPSTCVQFKPHCSNFTLDTIAPGWR 244
             FP VK +L GHIH +           +       PSTC+Q  P     T  T  PG+R
Sbjct: 180 ESFPQVKVVLFGHIHLDFQYQHVFSQRPSPIYFYGCPSTCLQVNPPVP--TDHTHLPGFR 237

Query: 245 TLELHADGTLTTEVHRLA 262
            L L  +GT  T V R+ 
Sbjct: 238 LLSLDPNGTHRTWVQRVE 255


>UniRef50_Q2BR54 Metallophosphoesterase n=1 Tax=Neptuniibacter caesariensis
           RepID=Q2BR54_9GAMM
          Length = 256

 Score =  235 bits (599), Expect = 2e-60,   Method: Composition-based stats.
 Identities = 82/262 (31%), Positives = 129/262 (49%), Gaps = 13/262 (4%)

Query: 9   LAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQD 68
           +A  A + +LQ++D HL  +    L GVN  + +Q VL  I       D ++ TGDL   
Sbjct: 1   MADTAPILLLQVSDMHLQQEPDMLLKGVNVEQRFQQVLVEIESQ--SADALLLTGDLTHH 58

Query: 69  QSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLD 128
               AY+     +     P  W+PGNHD    M       G   A+RV     W+++ LD
Sbjct: 59  A-PRAYERLVSYVDCLPYPAYWIPGNHDLPEEMARF---TGTELAQRVKTFGGWKLIFLD 114

Query: 129 SQV--FGVPHGELSEFQLEWLERKLAD-APERHTLLLLHHHPLPAGCSWLDQHSLRNAGE 185
           S     G   G LSE +L +L+ +L+  A ++H LL+LHHHP+P    W D+  L NA +
Sbjct: 115 SSSNPDGKGSGSLSETELSFLKAELSQTAADQHVLLVLHHHPVPVQSRWQDEICLANAEQ 174

Query: 186 LDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA----P 241
              ++  +P VK ++ GH+HQ  +L     +L + P+T  QFK    +  ++       P
Sbjct: 175 FWQIVDLYPQVKGVIFGHVHQSWELQRGDIQLFSVPATAAQFKAQTDSSEVENDPKLAGP 234

Query: 242 GWRTLELHADGTLTTEVHRLAD 263
            +   +LH+ G ++ +V RL  
Sbjct: 235 AYGRYQLHSCGKISQQVIRLPA 256


>UniRef50_Q1Q887 Metallophosphoesterase n=2 Tax=Psychrobacter RepID=Q1Q887_PSYCK
          Length = 279

 Score =  233 bits (595), Expect = 5e-60,   Method: Composition-based stats.
 Identities = 83/279 (29%), Positives = 129/279 (46%), Gaps = 21/279 (7%)

Query: 4   LLTLPLAG----EARVRILQITDTHLFAQ-----KHEALLGVNTWESYQAVLEAIRPHQH 54
           + + P++     + +V +LQITD HL +         +        S++A+++     + 
Sbjct: 1   MPSYPVSAVSTPDGQVNVLQITDLHLSSHVPASADETSSEVAVCQYSFEAIIKQALSKEI 60

Query: 55  EFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQD------- 107
             DLI+ TGDL      A Y H    +     P   + GNHD    M   L         
Sbjct: 61  RCDLIIVTGDLVNKVEPAIYDHIFTVLKETGIPFACIAGNHDVTDEMGEDLPFYQRTLIA 120

Query: 108 ---AGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLH 164
                   ++ +   E WQ+LLLDS + G   GE++   ++W+  +LA    +  L+ LH
Sbjct: 121 RACDPRLLSRHLIESEHWQLLLLDSSITGKVEGEITATDIDWVREQLASCA-KPALIALH 179

Query: 165 HHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTC 224
           HH LP    W+D H   NA E    +  F ++  ++ GH HQE    + G  + +TPSTC
Sbjct: 180 HHVLPVDSEWIDSHMAENAEEFWQHITPFENLSVIINGHTHQEQTRHYQGVTVYSTPSTC 239

Query: 225 VQFKPHCSNFTLD-TIAPGWRTLELHADGTLTTEVHRLA 262
            QFKP   NF  D  + PG+R L+L  +G + + V RL 
Sbjct: 240 YQFKPFEDNFAYDKNMRPGYRWLQLANNGKVASWVERLD 278


>UniRef50_B1KBF2 Metallophosphoesterase n=5 Tax=Proteobacteria RepID=B1KBF2_BURCC
          Length = 266

 Score =  232 bits (593), Expect = 8e-60,   Method: Composition-based stats.
 Identities = 64/216 (29%), Positives = 107/216 (49%), Gaps = 4/216 (1%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           I Q++D H+          V++   + A ++++   + E DL+V +GDL  + +   Y+ 
Sbjct: 4   IAQLSDIHVRPHGVLYQDAVDSNAMFSAAVDSLNRIRPEPDLVVISGDLTDEGTEGEYRK 63

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAK----RVFIGEQWQILLLDSQVF 132
             E +   R P V LPGNHD +  + +A  D    P +          + +++ LD+ V 
Sbjct: 64  LRELLVELRRPFVVLPGNHDDRGNLRAAFPDHAWLPDEGALSFALDVGELRLVALDTSVP 123

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
           G+ HGEL    L WL+ +LA+   R  ++++HH P   G  +LD + LRNA     VLA+
Sbjct: 124 GLHHGELGAETLAWLDTELAEHRNRTVVIVMHHPPFMTGIPYLDIYGLRNAEAFAAVLAR 183

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFK 228
             +V  +L GH+H+ +        +L  PST  Q  
Sbjct: 184 HDNVDRILAGHVHRSMQTRLGRVPVLTCPSTITQIA 219


>UniRef50_Q2KTP2 Putative phosphohydrolase n=1 Tax=Bordetella avium 197N
           RepID=Q2KTP2_BORA1
          Length = 271

 Score =  232 bits (592), Expect = 9e-60,   Method: Composition-based stats.
 Identities = 67/268 (25%), Positives = 124/268 (46%), Gaps = 10/268 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + I QI+D H+   + +A   V T       +  +       D+I+ +GDL      A Y
Sbjct: 1   MLIAQISDLHIRLPRQKAYRVVETDRYLPPAVATLNALDPAPDVIILSGDLTDFGRPAEY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV-FIGEQW--QILLLDSQV 131
            H  E +A  + P   +PGNHD + ++ +A  D      + + +  E +  ++++LD+  
Sbjct: 61  THLRELLAPLQTPFYLMPGNHDARDSLRAAFPDHPYLQGEFIQYTVEHFPLRLIMLDTVE 120

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHS-LRNAGELDTVL 190
               HG L   +L WLE +LA+AP R TL+ +HH P   G + +D+   L+ A EL+ ++
Sbjct: 121 PMQSHGVLCARRLNWLEERLAEAPGRPTLIAMHHPPFQTGIAHMDKIGLLQGAKELEALV 180

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQF----KPHCSNFTLDTIAPGWRTL 246
            ++ +++ ++ GH+H+ +   + G       ST  Q     +P   +   +   P +  L
Sbjct: 181 RRYDNIERIVSGHLHRTIFQRFGGTIASTCASTAHQVVLDLRPEGPS-AFNFEPPAY-HL 238

Query: 247 ELHADGTLTTEVHRLADTRFQPDTASEG 274
            L  +G L T    + +         +G
Sbjct: 239 HLWRNGQLITHHAYIGNYPGPYPFHEDG 266


>UniRef50_Q1MS94 Phosphodiesterase n=1 Tax=Lawsonia intracellularis PHE/MN1-00
           RepID=Q1MS94_LAWIP
          Length = 267

 Score =  228 bits (582), Expect = 1e-58,   Method: Composition-based stats.
 Identities = 61/238 (25%), Positives = 105/238 (44%), Gaps = 11/238 (4%)

Query: 12  EARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
           ++ ++ + I+DTH+ AQ        N     Q  ++ I+    +   ++ TGD+  D S 
Sbjct: 2   QSIIKFIHISDTHISAQGCLVYDN-NPRVKLQTCIDEIKRDHLDAAFLILTGDVTNDGSM 60

Query: 72  AAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV---FIGEQWQILLLD 128
             +    E ++    P   + GNHD + ++++A+ +    P   V           ++LD
Sbjct: 61  ECFSFLQEVLSELPMPWYLVMGNHDLKQSLFTAIPEYPRDPNGFVQFTVDTPVGLCIILD 120

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQ--HSLRNAGEL 186
           + +     G L   +L+WL  +L  A  +  LL  HH P   G   +D   HSL+N+ E 
Sbjct: 121 TTIANQSSGILCAARLDWLANELKQAT-KPVLLFFHHPPFSLGIPSMDAIVHSLKNSEEF 179

Query: 187 DTVLAKF-PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGW 243
             VL  +   ++++  GHIH+ +   WNG      PST  Q      NF  D    G+
Sbjct: 180 FAVLKPYKDKIRHMFVGHIHRPICGSWNGIPFSCAPSTAHQIA---LNFQSDKSVLGF 234


>UniRef50_Q3JU10 Ser/Thr protein phosphatase family protein n=72 Tax=Burkholderiales
           RepID=Q3JU10_BURP1
          Length = 325

 Score =  228 bits (581), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 62/246 (25%), Positives = 98/246 (39%), Gaps = 18/246 (7%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + +  I+D H+      A   V+T       +  +   +   D ++ TGDL        Y
Sbjct: 52  MLLAHISDLHIKRPGALAYRRVDTAAHLARCVARLNALEPRPDAVLVTGDLTDFGDDDEY 111

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDA----GISPAKRVFIGEQWQILLLDSQ 130
            H    +A    P   L GNHD + AM  A             +        +++ LDSQ
Sbjct: 112 AHLKALLAPLAMPYYLLVGNHDDRAAMRRAFPARVELQSGEFVQYALDLGPLRVIALDSQ 171

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLR--NAGELDT 188
           + G   G L + +L WL  +L  A +R  ++ LHH P   G   +D   L    +  LD 
Sbjct: 172 IPGASGGTLCDARLAWLADQLDAARDRPVIVALHHPPFACGIGHMDAMRLAPDASSRLDA 231

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQ------------FKPHCSNFTL 236
           +L + P+V+ +LCGH+H+ +   + G    A P+   Q            F      F +
Sbjct: 232 LLRRHPNVERVLCGHVHRTMFARFGGTIASAVPAPAHQVTFDLRDGGPSSFSMEPPAFAV 291

Query: 237 DTIAPG 242
              APG
Sbjct: 292 HRHAPG 297


>UniRef50_A3RQT5 Icc protein n=4 Tax=Ralstonia solanacearum RepID=A3RQT5_RALSO
          Length = 263

 Score =  227 bits (580), Expect = 3e-58,   Method: Composition-based stats.
 Identities = 60/237 (25%), Positives = 107/237 (45%), Gaps = 3/237 (1%)

Query: 18  LQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHF 77
            QITD HL A +   L+G  T+      ++AI  H    D+   TGD++QD+S  +Y+  
Sbjct: 20  AQITDLHLLADRESELMGYCTYSMLSDTVDAILEHDIRPDVCFLTGDISQDESVESYELA 79

Query: 78  AEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHG 137
              +     P  W+PGNHD +    +    +         +   W  + LD+   G   G
Sbjct: 80  RSELERLGIPVFWIPGNHDERDGAEAVFGASESIRRLTKLVTADWDFIYLDTCRQGAGEG 139

Query: 138 ELSEFQLEWLERKLADA--PERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPH 195
            L++   E    ++  +    ++  +++HHHP+P     LD + L +   L  +L +   
Sbjct: 140 YLNDQDFERFVSQVEASTGGGKNIAVVMHHHPVPTQTPLLDGYMLLDNERLLKMLDEHQQ 199

Query: 196 VKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADG 252
           VK ++CGH+H +  + +  + +   P+TC Q++   S    +    G+R  E    G
Sbjct: 200 VKLVICGHVHGDYRIRYGNQMIEMCPATCFQWEKGTSAMKTENWR-GFRVFEFSPSG 255


>UniRef50_B3Q6B8 Metallophosphoesterase n=8 Tax=Bradyrhizobiaceae RepID=B3Q6B8_RHOPT
          Length = 284

 Score =  227 bits (579), Expect = 4e-58,   Method: Composition-based stats.
 Identities = 66/214 (30%), Positives = 103/214 (48%), Gaps = 3/214 (1%)

Query: 12  EARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
              + I QI+D H+ A    A   V+T  +    + A+        ++V +GDL    S+
Sbjct: 11  PKPILIAQISDLHIKAPGELAYGKVDTAAALTRCVAALNALAPRPHVVVISGDLVDSPSA 70

Query: 72  AAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGI---SPAKRVFIGEQWQILLLD 128
             Y H    +A  + P V +PGNHD +  M +A          P  +++  +   I+LLD
Sbjct: 71  EEYAHLERLLAPLQIPFVAVPGNHDSRELMRTAFAQPTFPAEGPLNQLYPVDGIDIVLLD 130

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           S V G PHGEL    L+WLE  L+ +  R  LL LHH P   G   +D+ +LRNA E   
Sbjct: 131 SNVHGQPHGELEAGTLQWLEAVLSSSDHRPALLFLHHPPFATGIWHMDRQNLRNAAEFAL 190

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPS 222
           ++ ++P V+ +  GH+H+     + G      P+
Sbjct: 191 LVERYPWVRLVAAGHVHRATVTGFAGTVATICPA 224


>UniRef50_Q1LDS0 Metallophosphoesterase n=10 Tax=Proteobacteria RepID=Q1LDS0_RALME
          Length = 290

 Score =  227 bits (579), Expect = 4e-58,   Method: Composition-based stats.
 Identities = 62/251 (24%), Positives = 108/251 (43%), Gaps = 11/251 (4%)

Query: 11  GEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQS 70
             A   + Q+TD H+ A    +   V+T  + +  ++ +     + D+++ TGDL    S
Sbjct: 11  NAAPYLVAQLTDLHIKAGGKLSYRRVDTAGALRTAIDTLLAAPQQPDIVIVTGDLVDFGS 70

Query: 71  SAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQD--------AGISPAKRVFIGEQW 122
            + Y+   + +     P   LPGNHD +P++ +   D         G +P          
Sbjct: 71  ESEYRFLRDLLQPLPMPVRLLPGNHDHRPSLRAVFADHDYLFANGDGDAPVHYAIDAGPL 130

Query: 123 QILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRN 182
           +++  D  V G P G   +  L WL+  LA AP++ TL++LHH P   G   +D   L N
Sbjct: 131 RLVGFDCTVPGKPGGRAEDAGLAWLDATLAAAPKQPTLVMLHHPPFHTGIGHMDDQGLEN 190

Query: 183 AGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTI--- 239
           A   + ++A+ P V+ ++CGH+H+ +   + G   +  P    Q                
Sbjct: 191 APAFEAIIARHPQVERVVCGHLHRHITRRFGGTIAMTAPGPAHQVALDLDPQAASRFRME 250

Query: 240 APGWRTLELHA 250
            PG+     H 
Sbjct: 251 PPGYLLHWWHP 261


>UniRef50_D1A354 Metallophosphoesterase n=1 Tax=Thermomonospora curvata DSM 43183
           RepID=D1A354_THECD
          Length = 270

 Score =  225 bits (575), Expect = 9e-58,   Method: Composition-based stats.
 Identities = 70/248 (28%), Positives = 109/248 (43%), Gaps = 11/248 (4%)

Query: 17  ILQITDTHLFAQKHEALLGV-NTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           I Q++D HL A     +        + ++ + ++       D +V TGDLA       Y+
Sbjct: 4   IAQLSDIHLAAGADGRVDDRSGPVRALRSAVSSLLALPQRPDCVVLTGDLADRGLPVEYE 63

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQD--------AGISPAKRVFIGEQWQILLL 127
                ++    P   LPGNHD + A+  A  D           +P +        +++  
Sbjct: 64  RLRALLSPLPMPVFPLPGNHDDRAALREAFADRTAACAAPDPQAPFQYAVQVRGVRLVCC 123

Query: 128 DSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELD 187
           D+ V G  HGEL E +L+WL+  LA AP+  T++  HH P P G  +LD+  LR+A  L 
Sbjct: 124 DTTVPGESHGELDEERLQWLDAALAAAPDVPTVVATHHPPFPIGVRFLDEAGLRDAAALG 183

Query: 188 TVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQF--KPHCSNFTLDTIAPGWRT 245
            VLA+ P V+ ++ GH+H+           +  PST  Q             T  PG  +
Sbjct: 184 AVLARHPQVERVISGHVHRAAVGRIGEITAVTCPSTYRQIYLDTTSPGQAAVTGEPGGFS 243

Query: 246 LELHADGT 253
           L L  +G 
Sbjct: 244 LHLVGEGR 251


>UniRef50_A6D2K7 Ser/Thr protein phosphatase family protein n=1 Tax=Vibrio shilonii
           AK1 RepID=A6D2K7_9VIBR
          Length = 271

 Score =  225 bits (573), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 73/262 (27%), Positives = 115/262 (43%), Gaps = 16/262 (6%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + I Q+TD H+      A   V+T    Q  ++ I       D +V TGDL    +   Y
Sbjct: 1   MLIAQLTDLHIKQDGKPAYRKVDTLRCLQNAVQHINHLNPRPDYVVITGDLGDFGTEQEY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQD----AGISPAKRVFIGEQWQILLLDSQ 130
           Q   + +   + P   +PGNHD +  +   LQ             V   ++  +L LDS 
Sbjct: 61  QIIRQELEKLQLPLRVVPGNHDHRDNLRVGLQQLVDFDHPEFCNFVVEQDEQVLLGLDSS 120

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
           V G P+G LS   LEWL+ +LA    +  L+ LHH P+  G   +D  +L NA  L  VL
Sbjct: 121 VIGKPYGFLSSQTLEWLQSQLARLSNKSVLIFLHHPPMHVGLGHMDVQNLTNADSLYEVL 180

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGW-----RT 245
           ++F +V+ L  GH+H+ +   W    +   PS       H     LD  AP       R 
Sbjct: 181 SQFDNVRGLCAGHLHRPITATWRSIPVWVGPS-----HSHSVTLDLDPNAPSSFSLEPRA 235

Query: 246 LEL--HADGTLTTEVHRLADTR 265
           ++L    + ++ + +  + D+ 
Sbjct: 236 IQLLKFENDSVVSHISYIEDSD 257


>UniRef50_A1ZTZ2 Metallophosphoesterase n=1 Tax=Microscilla marina ATCC 23134
           RepID=A1ZTZ2_9SPHI
          Length = 251

 Score =  221 bits (564), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 73/251 (29%), Positives = 118/251 (47%), Gaps = 5/251 (1%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
            +R   ++D HL+  K       + ++S+  V++ +   +   D I+ TGD+A  Q   +
Sbjct: 3   TLRFAHLSDLHLYKYKDFMYHEHHPYQSFCNVVD-LLKQEDTLDFILITGDIAAKQEKES 61

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQ--V 131
           Y H  E +A    P  WLPGNHD    M        +     VF  +  + +LLDS    
Sbjct: 62  YFHVDELLAPLGTPYYWLPGNHDSAVLMKRIAPKVQV-QNTNVFETKGTRFILLDSTDRQ 120

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
                G L + +L +LE+ LA+A    T++ LHH  L    SW +   + N  +   ++ 
Sbjct: 121 EKAVAGFLPDDELRFLEKSLAEATNTSTIIALHHQLLATPGSWTNNLGVTNKNDFYKIID 180

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHA- 250
             P V+ ++CGHIH        G +  + P+T  QF P+   F LD +APG++ L +H  
Sbjct: 181 ACPQVQAVICGHIHHAHAWQRKGVQYFSAPATSYQFNPYAPEFALDELAPGYQVLSIHPK 240

Query: 251 DGTLTTEVHRL 261
              +  EV R+
Sbjct: 241 TRRVHCEVKRI 251


>UniRef50_B6R8M8 Ser/Thr protein phosphatase family protein n=1 Tax=Pseudovibrio sp.
           JE062 RepID=B6R8M8_9RHOB
          Length = 272

 Score =  220 bits (560), Expect = 6e-56,   Method: Composition-based stats.
 Identities = 60/260 (23%), Positives = 106/260 (40%), Gaps = 13/260 (5%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +   Q+TD H+ A    A   V+T    +  +  +   + + D +V +GDL    ++  Y
Sbjct: 1   MIFAQLTDIHIKAGGKFAYNCVDTLSHLRKAVAHLNTFRPQLDFVVISGDLVDLGNADEY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGI----SPAKRVFIGEQWQILLLDSQ 130
           + F + I     P   +PGNHD + AM  A  D G        +     +  +I+ LD+ 
Sbjct: 61  ELFRQEIDQLTMPFYVIPGNHDHRDAMREAFADHGYLSKEGALQFSIEKDGLRIIGLDTT 120

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNA-GELDTV 189
           + G   G     +  WL  +L    ++ TL+ +HH P   G   +D   L  A  +   V
Sbjct: 121 IPGKHDGHFDADKQAWLRAELTAHKDQPTLVFMHHPPFKTGIEHMDDIMLMRADDDFWPV 180

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFK-----PHCSNFTLDTIAPGWR 244
           +     +  + CGH+H+ +++  NG  +   P++  Q           +F +D   P  R
Sbjct: 181 VTGQSQILQIACGHVHRAIEVFKNGIPVSICPASGHQVTLDLEPDGEPSFVMD--PPAVR 238

Query: 245 TLELHADGTLTTEVHRLADT 264
                  G L   +  + D 
Sbjct: 239 IFR-WTGGELINHLSFIGDF 257


>UniRef50_A8U260 Ser/Thr protein phosphatase family protein n=1 Tax=alpha
           proteobacterium BAL199 RepID=A8U260_9PROT
          Length = 268

 Score =  219 bits (558), Expect = 1e-55,   Method: Composition-based stats.
 Identities = 56/220 (25%), Positives = 98/220 (44%), Gaps = 6/220 (2%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +  +QITD H+    +     V+T      ++  +         ++ TGDL  + S A Y
Sbjct: 1   MLFVQITDLHVRESGNPLAGRVDTAGFLDRMVTRLNALNPRPGAVLITGDLIDNGSEAEY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQ-----DAGISPAKRVFIGEQWQILLLDS 129
           +   + +A+   P     GNHD + A  ++       DAG +  +     +  ++L+LD+
Sbjct: 61  RLLRQRLAALDMPVYLALGNHDGREAFRASFTDLDYWDAGTAFVQYAVDLDGVRLLVLDT 120

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHS-LRNAGELDT 188
              G P G L   +L WL  +LA+     T++ +HH P+P G   +D    L  A     
Sbjct: 121 HEPGKPSGVLCLERLNWLSDRLAEDRSTPTVVAMHHPPVPVGMPNMDPSRLLAGAERFKE 180

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFK 228
           ++A  P+V+ +L GH+H+ +   + G  L   P    Q  
Sbjct: 181 LIAGAPNVERILAGHLHRSVTARFAGTVLDVMPGVAHQIH 220


>UniRef50_A5WBU9 Calcineurin phosphoesterase C-terminal domain protein n=1
           Tax=Psychrobacter sp. PRwf-1 RepID=A5WBU9_PSYWF
          Length = 340

 Score =  218 bits (557), Expect = 1e-55,   Method: Composition-based stats.
 Identities = 89/306 (29%), Positives = 130/306 (42%), Gaps = 51/306 (16%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVN-------------------------------- 37
             +  V ILQ+TD HL+    +A    +                                
Sbjct: 35  TDDGTVNILQLTDLHLYFDTPKATHEQDINKDSAHQTITGICQNNSAKRGNPHSADAINH 94

Query: 38  -------TWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVW 90
                   + S++A L          DLIV TGDL  +     YQH  + +     P   
Sbjct: 95  SVTPVIHNYASFEACLTQALSEDVRCDLIVVTGDLVSEIHPQLYQHLYQRLHQSGIPFAC 154

Query: 91  LPGNHDFQPAMYSALQDAGIS----------PAKRVFIGEQWQILLLDSQVFGVPHGELS 140
           + GNHD    +   L     S           ++       W+IL ++S V G   G + 
Sbjct: 155 IAGNHDVTDEIGKDLPFEQRSFEPHEPDSRLLSRYSMKLNGWEILFINSSVPGQIFGRIG 214

Query: 141 EFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLL 200
              L WL +KLA++     ++ +HHH LP   +W+D H  ++A E    +A F  +K ++
Sbjct: 215 NKNLYWLSQKLANS-HHPVIIAMHHHLLPMHSAWIDAHITQDATEFWQTVAPFNALKAVV 273

Query: 201 CGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA-PGWRTLELHADGTLTTEVH 259
            GH+HQ     + G +L +TPST  QFKP C +FTLD  A PG+R L L A+GTL + V 
Sbjct: 274 GGHVHQSSTRSYQGVQLYSTPSTGYQFKPGCDDFTLDDEAKPGYRWLSLKANGTLQSWVV 333

Query: 260 RLADTR 265
           RL D  
Sbjct: 334 RLEDNA 339


>UniRef50_B8J1S2 Metallophosphoesterase n=1 Tax=Desulfovibrio desulfuricans subsp.
           desulfuricans str. ATCC 27774 RepID=B8J1S2_DESDA
          Length = 276

 Score =  218 bits (555), Expect = 2e-55,   Method: Composition-based stats.
 Identities = 71/259 (27%), Positives = 111/259 (42%), Gaps = 12/259 (4%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + ILQ++DTHL      +   V+T     A    ++    + D+IV +GDLA      AY
Sbjct: 1   MHILQLSDTHLRGDNSLSFRVVDTRRCLDAATAHLKTMAQKPDIIVLSGDLADSGDLNAY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAK------RVFIGEQWQILLLD 128
               + ++    P   LPGNHD +  M   LQ    +  +           ++ +++++D
Sbjct: 61  HILYDALSPLGIPVYALPGNHDRRDRMRDVLQGWCPAAPEVSPHICYTVEMDELRLVMVD 120

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           S   G   G L      WL R LA  P+  TL+ +HH P   G   +D+    N G L  
Sbjct: 121 SMHPGSHSGHLFPAVEGWLARTLAQRPDVQTLVFMHHPPFMTGMGAMDE-PFENQGALAA 179

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTI---APGWRT 245
           +    P ++    GH+H+ +   W GR  +  PS  +Q     S    DT    APG+  
Sbjct: 180 IAGDNPQIRLCF-GHMHRPIITQWQGRLCMTAPSAAMQIDLDLSPEGGDTFRMEAPGY-L 237

Query: 246 LELHADGTLTTEVHRLADT 264
           L  +  G L T V ++   
Sbjct: 238 LHHYEHGILNTHVCQIPSD 256


>UniRef50_A4EV76 3',5'-cyclic-nucleotide phosphodiesterase, cpdA n=1 Tax=Roseobacter
           sp. SK209-2-6 RepID=A4EV76_9RHOB
          Length = 266

 Score =  216 bits (551), Expect = 6e-55,   Method: Composition-based stats.
 Identities = 61/256 (23%), Positives = 113/256 (44%), Gaps = 10/256 (3%)

Query: 12  EARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
           +  ++++ ++D H  A  +  +LG +     +A +  I     E    + TGDL +    
Sbjct: 2   DLALKLIWLSDLHFLATGN--VLGHDPRLRLEAAISHISACYPEAAACIITGDLVESAEP 59

Query: 72  AAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV---FIGEQWQILLLD 128
             Y+     +++     + L GNHD +  +        ++ A+ V       +  ++ LD
Sbjct: 60  EHYEALQTQLSNLPGQLLPLTGNHDDRDLLRQVFSLPNVAMAEFVQYRVDFPRLSVVALD 119

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           + V G  +G L   +LEWL++ L D  +   LL +HH P+  G   LD+ +LRN  EL  
Sbjct: 120 TLVSGQGYGFLCAQRLEWLQQTLDDCRDGPLLLAMHHPPMKLGLPILDEDNLRNGQELLE 179

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCS-----NFTLDTIAPGW 243
           +L    ++++LL GH+H+ +     G     + S   Q  P        +F+    AP +
Sbjct: 180 LLKGRNNIQHLLLGHVHRPVAGLTAGIPFKTSKSILYQAPPAVPAWDWESFSPAPEAPAY 239

Query: 244 RTLELHADGTLTTEVH 259
             +E+   G    E+ 
Sbjct: 240 TVIEVTETGVTLQEMC 255


>UniRef50_C1CX57 Putative Metallophosphoesterase; putative cAMP phosphodiesterase
           n=1 Tax=Deinococcus deserti VCD115 RepID=C1CX57_DEIDV
          Length = 267

 Score =  216 bits (550), Expect = 7e-55,   Method: Composition-based stats.
 Identities = 59/223 (26%), Positives = 103/223 (46%), Gaps = 9/223 (4%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + I Q++D H+ A+  +         + +  +  +       DL++ TGD  +    A Y
Sbjct: 1   MLIAQLSDPHVMAEPDDQ-----AAHALRRAVSHLLELPVLPDLVLITGDCTEHGEVAEY 55

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGI----SPAKRVFIGEQWQILLLDSQ 130
           + F   I     P   +PGNHD + AM SAL   G        + V      +++ LD+ 
Sbjct: 56  ETFRTLIQPLPMPVYVVPGNHDQRAAMLSALGRPGTLGLEGFMQYVVEAGPLRLIGLDTH 115

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
           + G   GEL   +L+WLE +L +AP R  ++ +HH P  +  + +D   LR+    + +L
Sbjct: 116 LPGQDAGELCAARLDWLEDRLTEAPGRPCVIFMHHPPARSSLNVMDGIGLRDPQAFEALL 175

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSN 233
           A+  +V+ +L GH+H  +     G  L+  P T   + P   +
Sbjct: 176 ARHSNVERVLTGHLHMAMTRRCGGTLLMTAPGTQHTWLPDLGH 218


>UniRef50_C6DHP5 Metallophosphoesterase n=5 Tax=Proteobacteria RepID=C6DHP5_PECCP
          Length = 253

 Score =  215 bits (548), Expect = 1e-54,   Method: Composition-based stats.
 Identities = 66/243 (27%), Positives = 104/243 (42%), Gaps = 6/243 (2%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++++Q++D HL AQ    L G +  +  +A +  I  H  + DL+V +GDL+ D S+A+Y
Sbjct: 1   MKLIQLSDLHLTAQGGN-LHGRDPEQQLKAAIADINAHHRDTDLVVISGDLSDDGSAASY 59

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQD--AGISPAKRVFIGEQWQILLLDSQVF 132
              A  +A  + P     GNHD +    +            + V       ++LLDS   
Sbjct: 60  TFLASVLAELQVPWRVTMGNHDDREMFLAQFPTLVDENGFVQSVTTVGDDCVILLDSLHA 119

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL--RNAGELDTVL 190
           G   G L   +L W  R+L  A  ++  L LHH P+  G   LD   L    A  L  V 
Sbjct: 120 GEVAGTLCSERLTWFARQLQAAEGKNVFLFLHHPPMSIGLPALDSVRLAPEAAEALYQVC 179

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFK-PHCSNFTLDTIAPGWRTLELH 249
            +F +V+++  GH+H+     W G        T  Q        F +   AP +      
Sbjct: 180 HRFGNVRHISAGHVHRPASGGWRGISFSTIRGTNHQSALRFAPGFEVSLEAPQYAIFLTT 239

Query: 250 ADG 252
            +G
Sbjct: 240 EEG 242


>UniRef50_A4C954 Cyclic 3',5'-adenosine monophosphate phosphodiesterase n=2
           Tax=Alteromonadales RepID=A4C954_9GAMM
          Length = 263

 Score =  215 bits (547), Expect = 2e-54,   Method: Composition-based stats.
 Identities = 74/256 (28%), Positives = 121/256 (47%), Gaps = 9/256 (3%)

Query: 11  GEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQS 70
            ++++R   I+D HLFA+ +E   GVN  +S + VL  +     +   ++  GDL QD S
Sbjct: 11  DKSQLRFAHISDCHLFAEVNECYFGVNCCDSLRLVLTDLAEQTLD--FVIFGGDLTQDHS 68

Query: 71  SAAYQHFAEGI--ASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV--FIGEQWQILL 126
            A+YQ FA+ +  A    P +WLPGNHD       A          R          + L
Sbjct: 69  LASYQLFAQLVNEAQLPCPVLWLPGNHDELDCYQQAFSMLPSHVISRAKWVQSPNLTVAL 128

Query: 127 LDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGEL 186
           ++S+    P G +    L  L  K+  A E++ ++  HHHP      +LD+H L N    
Sbjct: 129 VNSKGP-TPAGWVEPAHLTELVCKIKTAAEKN-VVFCHHHPKAI-AGYLDKHILENGEWF 185

Query: 187 DTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTL 246
            T LA+   V  +  GH+H +         + ATP+T +QF  + + +  + +  G+R +
Sbjct: 186 LTQLAQTEQVTTVFHGHVHNDYLQQHGELSIYATPATSIQFVKNSATWQQEDLGAGYRII 245

Query: 247 ELHADGTLTTEVHRLA 262
             +  G +++EV  LA
Sbjct: 246 HSNQLGEISSEVVWLA 261


>UniRef50_A7IH99 Metallophosphoesterase n=2 Tax=Xanthobacteraceae RepID=A7IH99_XANP2
          Length = 276

 Score =  215 bits (547), Expect = 2e-54,   Method: Composition-based stats.
 Identities = 71/271 (26%), Positives = 110/271 (40%), Gaps = 11/271 (4%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + I Q+TDTH+      A   V+T    +A +  I       D+++ TGDL      A Y
Sbjct: 1   MLIAQLTDTHIRRPGTLAYGVVDTALYLEAAVAHILALAPRPDVVIVTGDLTDFDDPAEY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDA----GISPAKRVFIGEQWQILLLDSQ 130
             F    A+   P + +PGNHD    + +A  +            V      ++++LDS 
Sbjct: 61  ARFRALTAALPMPLLPIPGNHDSSAGLLAAFPEIAARCDGGRVNYVVEDFPLRLVMLDST 120

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
           V+G PHG+L E  L +L+R L   P R   +  HH P   G   +D  +L +A  L+ V 
Sbjct: 121 VYGCPHGQLGEEGLAFLDRALGATPGRPAFVCAHHPPFLTGIRHMDVQNLSDAAGLEEVF 180

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQF--KPHCSNFTLDTIAPGWRTLEL 248
             +P V    CGH+H+ +   + G      P+                  + P   +L L
Sbjct: 181 GHWPQVLGFTCGHVHRAVTTTFAGIAATIGPAPAHAVSLALDPQAPPTFHMEPPSLSLHL 240

Query: 249 HADGTLTTEVHRLADTR-----FQPDTASEG 274
             DG + T    +         F PD  + G
Sbjct: 241 FTDGRVVTHRSFIGAYDGPHPFFGPDGKAIG 271


>UniRef50_P05675 Uncharacterized protein syc0937_d n=2 Tax=Synechococcus elongatus
           RepID=Y937_SYNP6
          Length = 255

 Score =  214 bits (545), Expect = 3e-54,   Method: Composition-based stats.
 Identities = 73/258 (28%), Positives = 118/258 (45%), Gaps = 12/258 (4%)

Query: 9   LAGEA-RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQ 67
            AG+A  + I QITD HL      AL G  T     AV   ++    +  L+     L++
Sbjct: 5   FAGDAMTLSIAQITDLHLLVDPQAALRGCVTTPRAAAVFGNLKQRSPDLLLLSGD--LSE 62

Query: 68  DQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLL 127
           D S A+Y+   + +     P + + GNHD    + + +        + V+  + W+I+ L
Sbjct: 63  DGSPASYERLRDWVEELGCPAIAIAGNHDQPERL-TEICGRSPFMGEPVYSIQGWRIIAL 121

Query: 128 DSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELD 187
           DS       G L   QL+WL+++L +     TLL+LHH P+  G + +D   L++  E  
Sbjct: 122 DSYQPKRIDGRLRGDQLDWLDQRLGEDSS-PTLLMLHHPPVLIGVTKMDAIGLKDGPEFL 180

Query: 188 TVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLE 247
            V+A    V+ +L GH HQ           L  P+T +QF           +  GWR+LE
Sbjct: 181 EVIAHHQQVRLVLSGHAHQAFIQGRGLTTFLGCPATAMQFDQP-------ELPAGWRSLE 233

Query: 248 LHADGTLTTEVHRLADTR 265
           L  DG+  +++H +    
Sbjct: 234 LEPDGSWRSQIHWVDTDS 251


>UniRef50_C8SU16 Metallophosphoesterase n=1 Tax=Mesorhizobium opportunistum WSM2075
           RepID=C8SU16_9RHIZ
          Length = 276

 Score =  214 bits (545), Expect = 3e-54,   Method: Composition-based stats.
 Identities = 60/237 (25%), Positives = 104/237 (43%), Gaps = 6/237 (2%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++I+Q+TD HL  Q  E   G +  +   + +  I  H  +  L V TGDL +  +  +Y
Sbjct: 1   MKIIQVTDVHLGRQG-ERRFGADLHQRLASCIAHINAHHADAALCVFTGDLTETGAPESY 59

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGI---SPAKRVFIGEQWQILLLDSQV 131
                 +++   P   LPGNHD +  + +A  +  +      + V    +  +L LD   
Sbjct: 60  ADLRTALSTLSVPWRLLPGNHDRRVNLVAAFPEIPVDENGFVQSVHDSGEEVLLFLDCLA 119

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
            G   GEL   +L WLE +L  +  R   + LHH P+  G   LD  +L   G L  +L 
Sbjct: 120 EGRVEGELCGTRLAWLEARLEQSAGRPAYIFLHHPPVALGLPQLDPLALEQPGRLLGLLR 179

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSN--FTLDTIAPGWRTL 246
              +V+++  GH+H+++     G    A      +F+        T++   P +  +
Sbjct: 180 DHGNVRHIFFGHVHRDIAGTVAGIPFSAQRGLHARFELALDRSSETVEQAPPSYAVI 236


>UniRef50_B0UF90 Metallophosphoesterase n=2 Tax=Methylobacterium RepID=B0UF90_METS4
          Length = 275

 Score =  214 bits (545), Expect = 3e-54,   Method: Composition-based stats.
 Identities = 68/273 (24%), Positives = 113/273 (41%), Gaps = 13/273 (4%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + I QITD HL  +   A     T    +  ++A+   Q   D+++ TGDL        Y
Sbjct: 1   MLIAQITDLHLRPRGRPAYRVAETNMLVERAVDALASLQPRPDVVLVTGDLTDCGLPEEY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVF---IGEQW--QILLLDS 129
                 +     P   +PGNHD + A+ +AL  A +  A   F   + + W  +++ LD+
Sbjct: 61  ALLRGLLGRLPLPVFVVPGNHDRREALRAALPAAWLPGAMEEFVQYVVDDWPVRLIGLDT 120

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAG-ELDT 188
            V G  HG L   +L +LE  LA   +R TL+ LHH P   G   +D+  L +    L  
Sbjct: 121 LVAGASHGALCARRLAFLEEALAAGGDRPTLVFLHHPPFACGMEGMDRIRLLDGEPRLRA 180

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCS---NFTLDTIAPGWRT 245
           ++   P+V+ +LCGH H+ + + + G      P    Q     +      L    P ++ 
Sbjct: 181 LIEAHPNVERILCGHHHRPIQVRYAGTIAQVAPGVAHQVALDLNPGRESGLVLEPPAFQL 240

Query: 246 LELHADGTLTTEVHRLA----DTRFQPDTASEG 274
                +  + + +  +        F  D    G
Sbjct: 241 HRYAPETGIVSHMVYVERYPGPFPFVLDPDYPG 273


>UniRef50_Q4JN56 Predicted 3',5'-cyclic-nucleotide phosphodiesterase n=1
           Tax=uncultured bacterium BAC13K9BAC RepID=Q4JN56_9BACT
          Length = 248

 Score =  213 bits (544), Expect = 3e-54,   Method: Composition-based stats.
 Identities = 67/250 (26%), Positives = 115/250 (46%), Gaps = 5/250 (2%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + ++QITD H+             +++    L+ I  H      +V TGDL+ D +  +Y
Sbjct: 1   MEMIQITDLHITKDIENIKNDCKPYQTLSTTLKHIEHHHSNVKDVVITGDLSNDYTRESY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
                 +  +++    LPGNHD      + + D  I+         +  +   D+ V G 
Sbjct: 61  MIIRNLLKKYQSTFYILPGNHDKLEH-INTICDEQITTNSIDLSMSKTLVYNFDTHVPGK 119

Query: 135 PHGELSEFQLEWLERKLADAPE-RHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKF 193
            +G L + Q+  L +KL    E    ++  HH  +  G  W+D+H   N+ EL  ++   
Sbjct: 120 TNGHLKKKQINELNKKLCINKEVDKVIIFTHHPIIKIGSEWIDEHISENSEELIQLMLSH 179

Query: 194 PHVKY-LLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDT-IAPGWRTLELHAD 251
              ++ +  GH+HQE +   N      TPSTC QFK     F L+T ++ G+R + LH D
Sbjct: 180 TDKEFKIFSGHVHQEFNCIKNNIEFFTTPSTCYQFKNQSEIFALETNLSYGYRVITLH-D 238

Query: 252 GTLTTEVHRL 261
            ++ T+V R+
Sbjct: 239 NSIRTKVLRI 248


>UniRef50_Q4ZTD8 Metallophosphoesterase n=4 Tax=Pseudomonas syringae group
           RepID=Q4ZTD8_PSEU2
          Length = 265

 Score =  213 bits (544), Expect = 4e-54,   Method: Composition-based stats.
 Identities = 63/253 (24%), Positives = 111/253 (43%), Gaps = 9/253 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + I  I+DTH+  +       V++     A ++ I       DLI+ +GDL  +     Y
Sbjct: 1   MLIAHISDTHVRPRGQLYQGVVDSNAMLAAAVDTINTLDPAPDLILFSGDLVDEGRPEEY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSAL--QDAGISPAKRVFIGEQ---WQILLLDS 129
               E +   R   + +PGNHD +  +  A    D  I+     F+       +I+ LD 
Sbjct: 61  AMARELLQPLRQKLLMIPGNHDHRQNLRDAFAEHDYFINDQDCSFVYSGSAPVRIIGLDI 120

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
            V    HG++++  + WL+  LA  P++ TL+++H  P  +G  ++D +       L  V
Sbjct: 121 SVPEQHHGDMTDTAIRWLDSTLALEPDKPTLIMMHQPPFSSGIPYIDAYRCERGERLAEV 180

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDT---IAPGWRTL 246
           ++++P ++ ++CGHIH+ + L + G  +   PST             D      P     
Sbjct: 181 VSRYPAIERIVCGHIHRFMQLRFGGTLMCTAPSTTTAIALRLHPEAADASYVEPPALLLH 240

Query: 247 ELHAD-GTLTTEV 258
              AD G +T  V
Sbjct: 241 HWKADTGLITHWV 253


>UniRef50_D2U008 3',5'-cyclic-nucleotide phosphodiesterase n=1 Tax=Arsenophonus
           nasoniae RepID=D2U008_9ENTR
          Length = 242

 Score =  213 bits (543), Expect = 5e-54,   Method: Composition-based stats.
 Identities = 62/238 (26%), Positives = 120/238 (50%), Gaps = 4/238 (1%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++I+Q+TD HLF+ + + L GV T++S   +++ I  ++ ++D I+ TGD++QD++  +Y
Sbjct: 1   MKIIQLTDLHLFSDRTQKLFGVVTYDSLNKIIDHILINEGDYDAIILTGDISQDETIESY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
           Q   E +     P  ++ GNHD++  +        I           W  + +D+  +G 
Sbjct: 61  QLANEMLIRLNKPIHYIHGNHDYKSNLDLIF---NIHNPIENLSIPYWDFISVDTVEYGK 117

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
             G +S+ +   L++K++++ E +  L++HHH L  G   +D   L N  +L   +    
Sbjct: 118 DSGFISDKEFRLLKKKISESKENNIALVMHHHCLKLGTPLIDDCMLLNNNQLLRFIDGEN 177

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADG 252
            +K ++CGH H    L  N   L   P+ C Q+K      +++ I+ G+R      + 
Sbjct: 178 KIKLIMCGHAHGNYKLKHNNSTLEVCPAVCFQWKKGTETPSIENIS-GYRKFSFFKEN 234


>UniRef50_Q7NZT6 3',5'-cyclic-nucleotide phosphodiesterase n=1 Tax=Chromobacterium
           violaceum RepID=Q7NZT6_CHRVO
          Length = 244

 Score =  212 bits (541), Expect = 9e-54,   Method: Composition-based stats.
 Identities = 80/244 (32%), Positives = 120/244 (49%), Gaps = 2/244 (0%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +RI Q+TD HLFA +   LLG +T  +   VL A+R  +   + ++ TGD++QD+S A+Y
Sbjct: 1   MRIAQLTDLHLFADRQGRLLGRDTHAALDGVLAALRTVE-GVEAVLLTGDVSQDESEASY 59

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
              AE +A+   P  W+ GNHD + AM                    W  + +DS V G 
Sbjct: 60  HLAAEALAALGVPVHWIAGNHDDRAAMTRVFAGYAFLRPLETLALGGWTFIGVDSCVAGQ 119

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
             G LS+  L+ L R L +A +    ++LHHHPL  G   LD   L  A     + A   
Sbjct: 120 DGGRLSDAGLDRLRRLLDEAGDGPAAVVLHHHPLAVGTPLLDDCMLAPASPFWRIAAASA 179

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTL 254
            +K  +CGH+H E  + + G+ L   P+TC Q++    +  +D    G+R  +   DG L
Sbjct: 180 ALKLAICGHVHGEHSIAYRGKMLEVGPATCFQWRRDACDIEIDD-RHGYRLFDFDGDGYL 238

Query: 255 TTEV 258
              V
Sbjct: 239 VRTV 242


>UniRef50_B1A0M0 Ser/Thr protein phosphatase family protein n=3 Tax=Bacteria
           RepID=B1A0M0_9BACT
          Length = 263

 Score =  212 bits (540), Expect = 1e-53,   Method: Composition-based stats.
 Identities = 66/245 (26%), Positives = 107/245 (43%), Gaps = 8/245 (3%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
           + + + ITD HL  +      GV T     A L+ I     +    V +GDLA+     A
Sbjct: 2   KTKFIHITDIHLVDEGLLLNGGVPT-ARLDACLDDISRWHPDAAFCVISGDLAEFAEVEA 60

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV---FIGEQWQILLLDSQ 130
           YQ     +A +  PC  L GNHD +    S   D      + V   F  EQ   L LD+ 
Sbjct: 61  YQALKARLAVYPLPCFLLIGNHDDRAVFQSVFPDHPKDMNEFVQHRFEIEQGVFLFLDTT 120

Query: 131 VFGV--PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
             G     G+L  ++L+WL+++LA+A ++ T L LHH P   G  ++D   L  A     
Sbjct: 121 KEGRDVHEGQLCSYRLDWLKQQLAEAGDKPTYLFLHHPPFEIGIPYVDNIRLIEAEAFAK 180

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLD--TIAPGWRTL 246
            L     ++++  GH+H+   ++W G    + PS   Q   + ++   +     P +  +
Sbjct: 181 ALRHGRDIRHVFYGHVHRMTYVNWRGISFTSLPSLNHQIPLNAASVNAEFCDEPPAYGVV 240

Query: 247 ELHAD 251
            +  D
Sbjct: 241 LIEDD 245


>UniRef50_D1U8L8 Metallophosphoesterase n=1 Tax=Desulfovibrio aespoeensis Aspo-2
           RepID=D1U8L8_9DELT
          Length = 282

 Score =  211 bits (538), Expect = 2e-53,   Method: Composition-based stats.
 Identities = 58/232 (25%), Positives = 98/232 (42%), Gaps = 13/232 (5%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWE---SYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
           + I  I+D H+     +    V+T      + A L +I       D ++ TGD+      
Sbjct: 1   MLIAHISDLHIRPHGEKLYDFVDTNALISRHVATLNSIAKTTDSPDAVLITGDIVNCGQK 60

Query: 72  AAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQD----------AGISPAKRVFIGEQ 121
             Y      +     P   +PGNHD    +  AL D           G    +       
Sbjct: 61  QEYAMARRILGQLTMPLYIIPGNHDNNANLLEALTDICPPLENVGKTGEHTIRYTIEEFP 120

Query: 122 WQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLR 181
            + ++LDS + G  HGE+   Q+ WLE++L     R T + +HHHPLP+G + +D     
Sbjct: 121 VRFIMLDSSIGGELHGEIGREQMAWLEKELQKGTGRETAVCMHHHPLPSGNAHMDAIKCH 180

Query: 182 NAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSN 233
           +   L  +L+++P+V  L+CGH H+ +  +     +   P    Q   H ++
Sbjct: 181 DGEALIEMLSRYPNVTRLICGHTHRSIFQNVGRILICTVPGAAHQVPFHSTD 232


>UniRef50_Q162P5 Ser/Thr protein phosphatase family protein, putative n=7
           Tax=Rhodobacterales RepID=Q162P5_ROSDO
          Length = 267

 Score =  211 bits (537), Expect = 3e-53,   Method: Composition-based stats.
 Identities = 65/220 (29%), Positives = 102/220 (46%), Gaps = 5/220 (2%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAV---LEAIRPHQHEFDLIVATGDLAQDQSSAA 73
           IL ITDTH+  +       ++T ++ + +   + +IR      D ++ +GDL+ D S+ +
Sbjct: 4   ILHITDTHIVPEGALVSGRLDTADALERLVARINSIRDQIGAVDAVLVSGDLSDDGSAES 63

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQD--AGISPAKRVFIGEQWQILLLDSQV 131
           Y+ F   +A    P   +PGNHD +  + +A  +  A   P   V       ++ LD+ V
Sbjct: 64  YKRFKRLVAPLGLPIHVIPGNHDGRATLRAAFAEQFAPTGPLNWVRSIGDLHLIGLDTLV 123

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
            G   G L+   L +L   L+ A     LL LHH P   G  ++D   L N   L  ++A
Sbjct: 124 EGQGGGRLAPESLSFLSDALSQAEGAPVLLALHHQPFLCGIGFMDAIGLSNKNALSEIVA 183

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHC 231
            +     LLCGHIH  +  D  G   ++ PS C  F   C
Sbjct: 184 GYQGPLRLLCGHIHSTMISDVGGHIAISCPSPCSSFAFDC 223


>UniRef50_A0NY27 Metallophosphoesterase n=2 Tax=Rhodobacteraceae RepID=A0NY27_9RHOB
          Length = 270

 Score =  210 bits (536), Expect = 3e-53,   Method: Composition-based stats.
 Identities = 64/252 (25%), Positives = 99/252 (39%), Gaps = 9/252 (3%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEF---DLIVATGDLAQDQSSA 72
           +I+QI+DTH+  +   A   V+T  +    +  I          DL++ TGDL +  +  
Sbjct: 3   KIIQISDTHIVPEGTLAYDQVDTAAALAETVATINRLLPRIGPVDLVIVTGDLTEHGTPE 62

Query: 73  AYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGI----SPAKRVFIGEQWQILLLD 128
            Y  F   +A    P   LPGNHD +  M  +           P       E + ++ LD
Sbjct: 63  EYDRFKNLMADLELPYRVLPGNHDRREPMRESFSGENWMPRTGPVNWQIDLEDFAVVGLD 122

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           S      HG L    L +L   L D  ++  L+  HH P   G   +D  +L +A  L +
Sbjct: 123 SLTENAAHGTLEAATLSFLTDALTDIGDKPALVGFHHPPFAVGIEAMDAQNLHDANSLGS 182

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLD--TIAPGWRTL 246
            L+       L+CGH+H+ +   ++G      P T             +  T  PG   L
Sbjct: 183 ALSLHSGQVRLVCGHLHRSIAGLFSGSLCQVCPGTSHAVTLDQRANAGNSLTKEPGGMLL 242

Query: 247 ELHADGTLTTEV 258
               DG   T +
Sbjct: 243 HEWRDGGFLTHL 254


>UniRef50_A9FYQ8 Phosphodiesterase n=6 Tax=Rhodobacteraceae RepID=A9FYQ8_9RHOB
          Length = 276

 Score =  210 bits (535), Expect = 4e-53,   Method: Composition-based stats.
 Identities = 60/257 (23%), Positives = 105/257 (40%), Gaps = 15/257 (5%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++I+ I+D HL     E + G++    +   L  +  +    D IV TGDL      AAY
Sbjct: 1   MKIIHISDIHLTIPGEE-MGGLDPHARFSRALANVAENHANADRIVITGDLTHWGEVAAY 59

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIG---EQWQILLLDSQV 131
           +     +A    P   L GNHD +        D  +     V      ++ +++ LDS  
Sbjct: 60  EALKSALAEVSIPVRLLIGNHDDRDTFRKVFTDHPVDANGFVNHAETLDETRLIYLDSVG 119

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL--RNAGELDTV 189
                G     + +WL+ +L  A      + LHH+P+P G    D+ +L   +      +
Sbjct: 120 DKTHAGHFCAVRRDWLKAELTAAGR--ARIFLHHNPMPVGLPAEDKIALVPEDRAAFKAL 177

Query: 190 LAKF-PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTL---DTIAPGWRT 245
           L  +   + Y+  GH+H  +   + G    + PST  Q  P  +   L     +AP +  
Sbjct: 178 LEAYGDRIDYIHFGHVHAPIHGRFAGIPFASVPSTGNQSLPDLNETELLKGAPMAPAYFV 237

Query: 246 LELHADGTLTTEVHRLA 262
           L +  +    T +H++ 
Sbjct: 238 LSIDGN---DTTIHQIP 251


>UniRef50_A7BW21 Cyclic AMP phosphodiesterase n=1 Tax=Beggiatoa sp. PS
           RepID=A7BW21_9GAMM
          Length = 248

 Score =  210 bits (535), Expect = 4e-53,   Method: Composition-based stats.
 Identities = 79/253 (31%), Positives = 122/253 (48%), Gaps = 16/253 (6%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLA-QDQSSAA 73
           + I Q+TDTH+    +    G+     +  VL A+   + +  L+V +GDLA  +    A
Sbjct: 6   LVIAQVTDTHIGP-MNIKYRGIEPRRQFLDVLRALTKMKPD--LLVLSGDLAAVEGEPEA 62

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQ----DAGISPAKRVFIGEQWQILLLDS 129
           Y    + +     P + + GNHD    M +A Q    D            +  ++L LDS
Sbjct: 63  YAWIRDVLVKLPYPYLVMAGNHDHVVRMNNAFQLQETDISQGMLFFSRTIKDKRLLFLDS 122

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLD-QHSLRNAGELDT 188
             +      +++ QLEWL+ +L D   +  LL +HH PL  GCS++D  H L+N  E+  
Sbjct: 123 SPY-----RIAKQQLEWLKEELNDY-HKQVLLFVHHPPLRCGCSFMDDHHGLQNGEEVWQ 176

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLEL 248
           VL +FP V+++ CGH H E  +  +G+ +  TPST  Q       F +D   PGWR +E 
Sbjct: 177 VLEQFPQVQHIFCGHYHTEKTIIQSGKSVHLTPSTVFQINAENPKFAIDHTNPGWRMIE- 235

Query: 249 HADGTLTTEVHRL 261
             D  + T V  L
Sbjct: 236 WDDTQVHTYVKYL 248


>UniRef50_C6CXY6 Metallophosphoesterase n=1 Tax=Paenibacillus sp. JDR-2
           RepID=C6CXY6_PAESJ
          Length = 276

 Score =  210 bits (535), Expect = 4e-53,   Method: Composition-based stats.
 Identities = 63/250 (25%), Positives = 97/250 (38%), Gaps = 8/250 (3%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
            +    +TDTH+       L  ++     +AV   I     +   IV +GDL QD     
Sbjct: 3   PILFAHLTDTHVNVPGKTPLFSIDGGAKLRAVFAEIGRLSEKPAFIVISGDLTQDGDVED 62

Query: 74  YQHFAEGI----ASFRAPCVWLPGNHDFQPAMYSAL--QDAGISPAKRVFIGEQWQILLL 127
           Y+   + I    A+   P     GNHD +P        ++         F+ E+ +I++L
Sbjct: 63  YKFLRQLIDEEQAALGIPVYVALGNHDSRPFFREGYLNEEPSEESYHYSFMHEELRIIML 122

Query: 128 DSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELD 187
           ++QV G   G L E QL+WL  +LA      T+++LHH  +      +D H L N   L 
Sbjct: 123 NTQVPGKHDGRLDEAQLDWLSNELASTAPAGTIVVLHHPVVATPSELMDSHLLENPEALA 182

Query: 188 TVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLE 247
            V+A    V  LL GHIH      +      A         P            G+  + 
Sbjct: 183 DVIA-GTDVIGLLSGHIHFNSIGLFRNIPSAAGTGVAFGLDPTSKGSMKFIDNSGYNLV- 240

Query: 248 LHADGTLTTE 257
           L  +G +   
Sbjct: 241 LVKNGQMIVT 250


>UniRef50_Q89MQ1 Bll4141 protein n=1 Tax=Bradyrhizobium japonicum RepID=Q89MQ1_BRAJA
          Length = 283

 Score =  210 bits (534), Expect = 5e-53,   Method: Composition-based stats.
 Identities = 67/271 (24%), Positives = 114/271 (42%), Gaps = 13/271 (4%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           + + ITDTHL A     L G++      A +  I  HQ +    V TGDL       +Y 
Sbjct: 4   KFIHITDTHL-ANPGLKLYGLDPRARLDAAIADINKHQSDAAFAVVTGDLTHWGEPESYA 62

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV---FIGEQWQILLLDSQVF 132
           +FA+ +A+ + P + + GNHD + A    L+ A       V    I E    + LD+   
Sbjct: 63  NFADAMAALKIPYIAMVGNHDKRVACLDGLKAAPRDSNGFVQGTRITEHGLFVFLDTLDE 122

Query: 133 GVPHGELSEFQLEWLERKLADAP-ERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
               GE+   +L WL   LA AP +   ++ +HH P P G   +D+ SL+ + E   V+A
Sbjct: 123 TSHAGEMCAKRLGWLASTLAAAPADMPFVVFMHHPPFPVGVHAMDEISLKQSPEFAEVIA 182

Query: 192 KF-PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA----PGWRTL 246
            +   +++L  GH+H+ +   +          T  Q          + +A    P +  +
Sbjct: 183 PYRSRIRHLFFGHVHRPIFGSYGKIPFSTLRGTNHQVWFELDAAAAEHLASHEPPAYGVV 242

Query: 247 ELHADGTLTTEVHRLAD---TRFQPDTASEG 274
            +  +  +      L +     F+P    +G
Sbjct: 243 LIDGENLVVHSHDFLDESLRFPFEPPAGVDG 273


>UniRef50_C5T0E1 Metallophosphoesterase n=1 Tax=Acidovorax delafieldii 2AN
           RepID=C5T0E1_ACIDE
          Length = 267

 Score =  208 bits (531), Expect = 1e-52,   Method: Composition-based stats.
 Identities = 72/268 (26%), Positives = 107/268 (39%), Gaps = 18/268 (6%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           + + +TDTHL  +   AL G++     Q  +E I  H  +   +V TGDL       AY+
Sbjct: 6   KYIHLTDTHLVKEAG-ALYGLDPKLRLQQAVEHINCHHADARAVVITGDLTHYGHDNAYE 64

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGI---SPAKRVFIGEQWQILLLDSQVF 132
           H  E +A+   P   + GNHD +                  + V   E++  + LD+   
Sbjct: 65  HLRECLAALSMPVYPILGNHDSRVNFVRHFPHIPCDANGFVQYVVQLERYTAIFLDTNEP 124

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
           GV  G   E + +WL   L  A E+  LL +HH   P G + +D  SLRN G  +  +A 
Sbjct: 125 GVHWGVFCEQRAQWLRAAL-QAAEKPVLLFMHHPFFPIGITSMDDISLRNTGPFEAAIAS 183

Query: 193 F-PHVKYLLCGHIHQELDLDWNGRRLLATPST----CVQFKPHCSNFTLDTIAPGWRTLE 247
           F P + +   GHIH+ +     G       ST     +  +    N       P +  L 
Sbjct: 184 FEPRIAHCFFGHIHRPIFGSVRGIPYSTLRSTNHDVALVLQDPSLNIVGKNENPQYGVLL 243

Query: 248 LHADGTLTTEVHRLADTRFQPDTASEGY 275
           L     L      L         +SEGY
Sbjct: 244 LREGQVLLHLEDYLD--------SSEGY 263


>UniRef50_Q47WJ3 Cyclic AMP phosphodiesterase n=1 Tax=Colwellia psychrerythraea 34H
           RepID=Q47WJ3_COLP3
          Length = 263

 Score =  208 bits (531), Expect = 1e-52,   Method: Composition-based stats.
 Identities = 75/261 (28%), Positives = 120/261 (45%), Gaps = 15/261 (5%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
                +   QITD+HLF+       G N   + + VL +I  +      I+ TGDL QD 
Sbjct: 9   PNNQPITFAQITDSHLFSSVDGLHHGHNVLANLKKVLLSICDN-PSIKYIIFTGDLTQDH 67

Query: 70  SSAAYQHFAEGIASFRA--PCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLL 127
           +  +YQ+F + +       P  +L GNHD    +      +    A +      WQ+ L+
Sbjct: 68  TEQSYQNFVDCVLECHITVPIYYLAGNHDEPKLLDKYFSASPF-QADKEINLSHWQVQLV 126

Query: 128 DSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELD 187
           DS+    P G + E  L  L+  +     ++ LL++HHHP+  G  ++D+H L+N     
Sbjct: 127 DSKSA-TPAGYVGEQALVKLKDAIQK--NKNQLLMMHHHPIDVG-YFIDKHGLQNKDAFW 182

Query: 188 TVLAKFPHVKYLLCGHIHQELDLDWN-------GRRLLATPSTCVQFKPHCSNFTLDTIA 240
            V+  + ++K + CGH+H ++ L             L   P+T +QF P        +  
Sbjct: 183 QVINSYDNIKAIACGHVHGDMTLTNAITSPINEPVVLYTCPATSIQFDPTVDGVAALSKG 242

Query: 241 PGWRTLELHADGTLTTEVHRL 261
           PG+R   L+ADG L TEV  L
Sbjct: 243 PGYRLFSLYADGQLNTEVVML 263


>UniRef50_Q1GM28 Metallophosphoesterase n=3 Tax=Rhodobacteraceae RepID=Q1GM28_SILST
          Length = 270

 Score =  208 bits (529), Expect = 2e-52,   Method: Composition-based stats.
 Identities = 57/247 (23%), Positives = 110/247 (44%), Gaps = 13/247 (5%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQH---EFDLIVATGDLAQDQSSAA 73
            +Q+TDTH+ ++   A    +T  +    ++ I          D +V TGDL    S+  
Sbjct: 4   FIQLTDTHIVSEGSLAYGRSDTATALARAVDTINSRLPVLDPVDCVVVTGDLTDHGSAEE 63

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGI----SPAKRVFIGEQWQILLLDS 129
           Y H  + +A    P   +PGNHD + AM +A           P +       + ++ LD+
Sbjct: 64  YAHLRQLLAPLNVPVRAIPGNHDTREAMRAAFATEDWMPASGPIQWHHDFGPFAMVGLDT 123

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
            V G P+G + E  L +L R L   P++  ++  HH  +P+G + +D+++LRN   +  +
Sbjct: 124 LVEGAPYGMVCEAGLGFLARSLKTTPDKPLVVATHHPWIPSGMADMDRNNLRNGPAMLDL 183

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA--PG----W 243
           L +     +++ GH+H+ +    +G      P+ C           ++++   PG    +
Sbjct: 184 LREHDAPVHVISGHLHRAMSALVDGVLHQVAPAPCHAVHLDQRADAVNSLVLEPGQVTVY 243

Query: 244 RTLELHA 250
              ++  
Sbjct: 244 NWHDVTG 250


>UniRef50_B9QUB7 Ser/Thr protein phosphatase family protein n=1 Tax=Labrenzia
           alexandrii DFL-11 RepID=B9QUB7_9RHOB
          Length = 278

 Score =  207 bits (528), Expect = 3e-52,   Method: Composition-based stats.
 Identities = 63/260 (24%), Positives = 101/260 (38%), Gaps = 14/260 (5%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           I  ITD HL  +        +T    +  + A+       D +V TGDL        Y  
Sbjct: 4   IAHITDLHLRPRGLACYRVSDTNMLAERAILALNGLTPRPDAVVLTGDLTDKSDPREYAL 63

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAK------RVFIGEQWQILLLDSQ 130
             + ++    P   +PGNHD    M   +                       +++ LD+ 
Sbjct: 64  ARQILSRLAMPVFMIPGNHDGSADMRREMSGFPGMDGDVDGKLCYTAEIGDVRLIALDTN 123

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
           + G P+GEL   QL WL  +L+D   R TL+ LHH P  +G   +D   L +A  L  V+
Sbjct: 124 IPGKPNGELGTPQLNWLSDRLSDD-NRPTLIALHHPPALSGIQHMDAIGLNDANALAEVI 182

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQF-----KPHCSNFTLDTIAPGWRT 245
               H++ LLCGH+H+ +  ++ G+ +   PST  Q      +     F  +   P +  
Sbjct: 183 GPHKHIQRLLCGHLHRPIIAEFAGKIMTLAPSTGHQVVLDLTEDGPPMFNFE--PPAYFL 240

Query: 246 LELHADGTLTTEVHRLADTR 265
                     T +  +    
Sbjct: 241 HHHTLQAGTVTHMAYVEAYP 260


>UniRef50_B6J9P9 3',5'-cyclic-nucleotide phosphodiesterase n=7 Tax=Coxiella burnetii
           RepID=B6J9P9_COXB1
          Length = 246

 Score =  207 bits (528), Expect = 3e-52,   Method: Composition-based stats.
 Identities = 54/237 (22%), Positives = 110/237 (46%), Gaps = 4/237 (1%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++I Q++D HL ++  E   G   + +   V  AI     + D+I  TGD++ D +  +Y
Sbjct: 6   IKIAQVSDLHLTSENCETSRGR--YSNAMNVFSAI-SLSGQHDMIFITGDISDDYTENSY 62

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
           +   E +         +PGNHD    M   + +  +   + V     +  L +++ V G 
Sbjct: 63  KQLLEMLKKLTCRVFVIPGNHDDFNLMNKIIPEKYLFSPETVTSFNTFDFLFVNTVVNGE 122

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
            HG L+   L  L+  L ++  +   +++HH+P+P      D++ L N  +   ++  + 
Sbjct: 123 IHGLLTGQDLSLLQNHLENSGNKKKCMIMHHNPIPLNRKIYDKYMLLNYQDFLRIICLYD 182

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHAD 251
           +VK ++ GH+H +  + +      + P+TC Q K   S+  ++    G++   L  +
Sbjct: 183 NVKLVIFGHVHNDYTISYRQTLFSSAPATCYQIKKFESDIIIEEK-YGYKNYFLFEN 238


>UniRef50_B6WYD4 Putative uncharacterized protein n=1 Tax=Desulfovibrio piger ATCC
           29098 RepID=B6WYD4_9DELT
          Length = 274

 Score =  207 bits (527), Expect = 3e-52,   Method: Composition-based stats.
 Identities = 68/259 (26%), Positives = 104/259 (40%), Gaps = 12/259 (4%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + ILQI+D HL      +   V+T    +     +       D IV TGDLA      AY
Sbjct: 1   MEILQISDLHLRGDGKLSFRKVDTPACLRTAAAYLHALNRMPDAIVITGDLADSGDEHAY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSAL-----QDAGISP-AKRVFIGEQWQILLLD 128
               E +     P   +PGNHD +  M + L     +++ + P         + ++++LD
Sbjct: 61  HMLYEALGDLPVPIYAVPGNHDRRDRMRAILKGWVPEESPVPPRVCHCVDMGELRLVMLD 120

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           S   G   G   E    WL+  L +   R  L+ +HH P   G   +D+     A  L  
Sbjct: 121 SMEPGSHSGHCPEAMARWLDACLQEDSSRPALVFMHHPPFITGMGAMDE-PFEGADLLRD 179

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA---PGWRT 245
           VL++ P  + L CGH+H+ +   W     L  PS  +Q     S    DT     PG+  
Sbjct: 180 VLSRAPWAR-LCCGHMHRPIFTAWAQGLALTVPSISMQIDLDLSPEGGDTFRMEMPGY-M 237

Query: 246 LELHADGTLTTEVHRLADT 264
           L       L + V ++   
Sbjct: 238 LHHWDGSHLNSHVCQIPAD 256


>UniRef50_B3TB35 Putative calcineurin-like phosphoesterase n=1 Tax=uncultured marine
           microorganism HF4000_APKG8K5 RepID=B3TB35_9ZZZZ
          Length = 245

 Score =  207 bits (527), Expect = 3e-52,   Method: Composition-based stats.
 Identities = 58/195 (29%), Positives = 95/195 (48%), Gaps = 9/195 (4%)

Query: 42  YQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAM 101
            +  ++ +     + D++VATGDL    S   Y +  E +A        +PGNHD + A+
Sbjct: 2   LRDCVDHLSALDPQPDIVVATGDLTYLGSPEEYAYLRELLAPLECSVFLIPGNHDGRGAL 61

Query: 102 YSALQDAGISP---------AKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLA 152
             A  D G  P                   +++ LD+ V G P G L E Q+ WL+  L 
Sbjct: 62  REAFADQGYFPEPSGGDRDFLNYTVEDYPLRLIALDTVVPGKPGGWLDETQIAWLDECLG 121

Query: 153 DAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDW 212
           ++P R T++L+HH P  +G + +D     N+  L  V+A+ P V+ ++CGH+H+ + L W
Sbjct: 122 ESPSRPTMILMHHPPYVSGIAHMDAMMCGNSDALGAVVARHPQVERIICGHLHRPVHLRW 181

Query: 213 NGRRLLATPSTCVQF 227
           +G  +   PS   Q 
Sbjct: 182 HGTVVCTAPSPGFQV 196


>UniRef50_Q2J948 Metallophosphoesterase n=5 Tax=Actinomycetales RepID=Q2J948_FRASC
          Length = 287

 Score =  207 bits (526), Expect = 5e-52,   Method: Composition-based stats.
 Identities = 67/262 (25%), Positives = 113/262 (43%), Gaps = 8/262 (3%)

Query: 4   LLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATG 63
           +L  P A      ++QI+DTH+  +       V+T+ + + VL+ I     +   ++ TG
Sbjct: 3   ILLDPTAHTPTHILIQISDTHIVREGELMHGKVDTYAALRTVLDQIEASTLKIGALLLTG 62

Query: 64  DLAQDQSSAAYQHFAEGI----ASFRAPCVWLPGNHDFQPAMYSAL--QDAGISPAKRVF 117
           DLA      AYQ   + +    A    P ++  GNHD +      L   +        V 
Sbjct: 63  DLADRGDLLAYQRLRDLVEPAAARLGTPVLYGVGNHDSRGPFREGLLGAEPTAEAHDYVH 122

Query: 118 IGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQ 177
                +I++LD+   G   G LS  QL WL  +LA A    T+L LHH P+P+  + ++ 
Sbjct: 123 WVGDLRIIMLDTTEPGEHSGFLSTAQLRWLADELATAAPDGTILALHHPPVPSPLAMVNS 182

Query: 178 HSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLD 237
             L     L  VLA    VK +L GH H       +G  +    +T  + +       + 
Sbjct: 183 LLLAEPQNLADVLA-GSDVKIVLAGHAHHASAGVLSGVPVWVAGATAYRIRTLGPADRIT 241

Query: 238 TIAPG-WRTLELHADGTLTTEV 258
            +  G +  ++++ +G + T V
Sbjct: 242 GLVGGEYTRIDVYPEGAVATAV 263


>UniRef50_A2C6L9 Serine/threonine specific protein phosphatase n=2
           Tax=Prochlorococcus marinus RepID=A2C6L9_PROM3
          Length = 263

 Score =  206 bits (524), Expect = 7e-52,   Method: Composition-based stats.
 Identities = 75/253 (29%), Positives = 113/253 (44%), Gaps = 10/253 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +R++Q++D HL A  H  +   N   ++Q  L+      H  DL++ TGDL  D+S   Y
Sbjct: 1   MRLVQLSDPHLVAFNHRLVRDQNPLLNFQCALQQ--GMSHSPDLLLITGDLCHDESWCGY 58

Query: 75  QHFAEGIASFR--APCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVF 132
               + + +         LPGNHD  P    A        A      +  +++LL S V 
Sbjct: 59  VLLRDELQNLSPSIKVAVLPGNHDN-PLFIKAALGRHAFTAPADLNLDGVRLILLSSHVS 117

Query: 133 GVPHGELSEFQLEWLERKLA--DAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
           G   G+L E QL+WL+ +L+  +   R  ++ +HH PLP G SWLD   L +   L  +L
Sbjct: 118 GRTAGQLGESQLQWLDSRLSDIEQSGRPLVVAVHHPPLPIGSSWLDAIGLVDGEALIKLL 177

Query: 191 AKFPHVKYLLCGHIHQELDL---DWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLE 247
                +  ++CGHIHQ       +     +L  PST   FK            PG R +E
Sbjct: 178 TPVDELCAVVCGHIHQHWQGLFPERKDVLVLGCPSTLCSFKAVQPCLLGREDEPGGRLIE 237

Query: 248 LHADGTLTTEVHR 260
           L   G    ++ R
Sbjct: 238 LDESGNFFEKLLR 250


>UniRef50_A5FX65 Metallophosphoesterase n=1 Tax=Acidiphilium cryptum JF-5
           RepID=A5FX65_ACICJ
          Length = 282

 Score =  205 bits (522), Expect = 1e-51,   Method: Composition-based stats.
 Identities = 68/239 (28%), Positives = 100/239 (41%), Gaps = 10/239 (4%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + I  I+D H+      A   V T    + VL  +       + IV TGDL        Y
Sbjct: 1   MLIAHISDLHVRPVGRPANRVVETNMMAERVLRRVATLDPAPEAIVITGDLVDCGRDDEY 60

Query: 75  QHFAEGIAS-FRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVF-----IGEQWQILLLD 128
           +     +      P   +PGNHD + A  +AL       A   F         +++++LD
Sbjct: 61  EELNRLLDRKLPCPVYVVPGNHDRREAFRAALGHLPGVTADPDFVQYSADIGPFRLIMLD 120

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           S V G  HGEL   +L +L+  L  A  R  L+ LHH P+  G + +D   LR++  L  
Sbjct: 121 SVVPGAGHGELCPQRLAFLDAALEAAAGRKVLIGLHHPPVITGVAAMDSIMLRSSEALLA 180

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLE 247
             A   +V  +L GH H+ +     G  LL+ P+       H S  T D  A  +  LE
Sbjct: 181 RAAAHGNVAAILSGHHHRAIHAAHGGTMLLSVPAAAG----HQSEITFDPKARAYFHLE 235


>UniRef50_C1AX97 3',5'-cyclic-nucleotide phosphodiesterase n=24 Tax=Actinomycetales
           RepID=C1AX97_RHOOB
          Length = 318

 Score =  204 bits (519), Expect = 3e-51,   Method: Composition-based stats.
 Identities = 68/280 (24%), Positives = 111/280 (39%), Gaps = 19/280 (6%)

Query: 12  EARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
                +L ++DTHL          V++  + + ++  I       D +V TGDL      
Sbjct: 16  RPSHVVLHLSDTHLV-DDDLLYGAVDSEATLRQIVTEIEASHARPDALVFTGDLTDRGQP 74

Query: 72  AAYQHFAEGIAS----FRAPCVWLPGNHDFQPAMYSAL--QDAGISPAKRVFIGEQWQIL 125
            AY+   E +        A  +W  GNHD +    + L  Q+    P   V   +  +I+
Sbjct: 75  GAYEKLREIVEPVAATLGAQVIWAMGNHDDRGHFRAELLGQEPTYEPVDHVHDVDGLRII 134

Query: 126 LLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGE 185
            LD+ V G  HGE+SE QL WL ++LA      ++L LHH P+P          LR+   
Sbjct: 135 TLDTTVPGHHHGEISESQLIWLAQQLAIPAPHGSILALHHPPVPCVLDLAVLVELRDQPR 194

Query: 186 LDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTL--DTIAPGW 243
           L  VL +   V+ +L GH+H      + G  +    +TC     +     L     A G+
Sbjct: 195 LADVL-RGSDVRSILAGHLHYSTTATFAGIPVSVASATCYTQDLNVPAGALRGRDGAQGY 253

Query: 244 RTLELHAD---------GTLTTEVHRLADTRFQPDTASEG 274
             + ++ +         G+  T    +          +EG
Sbjct: 254 NLVHVYPETVVHSVVPIGSYDTVGEYVTAEETARRLVAEG 293


>UniRef50_C6A0T0 Predicted phosphohydrolase n=6 Tax=Thermococcus RepID=C6A0T0_THESM
          Length = 504

 Score =  203 bits (518), Expect = 4e-51,   Method: Composition-based stats.
 Identities = 57/260 (21%), Positives = 113/260 (43%), Gaps = 18/260 (6%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++I  I+DTH+ +           ++ Y   L A   +  +++L++ TGD+  D     Y
Sbjct: 2   IKIAHISDTHITSG--------EAYKGYAYDLIANEINTLDYNLVIHTGDVTNDGLREEY 53

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
           +  +  +   + P + LPGNHD +   Y   Q   I P   ++  +   I+  DS +  +
Sbjct: 54  ERASYELKKIQKPLIVLPGNHDARNVGYELFQ-KYIGPLNGIYEWKDLVIIWTDSTIPDL 112

Query: 135 PHGELSEFQLEWLERKLADAPERH-TLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKF 193
             G +  ++  WL+ KL +   +   ++  HHH +P   +  +++ L NAG++  +L K 
Sbjct: 113 NDGRIGGYKFRWLKEKLEEYSHKKFKIVASHHHLVPLPDTGRERNVLFNAGDVLELLLKH 172

Query: 194 PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGT 253
             V   LCGH H        G  L+   S C   +      T       +  +++  +G 
Sbjct: 173 E-VNLYLCGHKHVPNIYSVEG--LVVANSGCTSCRK-----TRKGDVNSYNMIKIKDNGK 224

Query: 254 LTTEVHRLADTRFQPDTASE 273
           ++  + R+ +   + D   +
Sbjct: 225 ISVTIKRVTEDIHKRDFTVK 244



 Score = 77.2 bits (189), Expect = 6e-13,   Method: Composition-based stats.
 Identities = 36/236 (15%), Positives = 84/236 (35%), Gaps = 18/236 (7%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           RI+QI+      + + +       +  +  ++AI     + DL+V  GD+ +      Y+
Sbjct: 258 RIIQIS------ESNVSDRIYFREKVLKNAIKAINERY-KPDLVVHCGDIVEVGIERYYK 310

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVP 135
                    +   + +PG++D     Y   ++    P   +   E +  + + S  +  P
Sbjct: 311 KAYALWEKIKGKKIIVPGHNDITYLGYELFREYFGEP--EIIENENFTFIPIISAQYETP 368

Query: 136 HGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPH 195
            G +     + L   L    +   ++++HH+  P   S  +   L + G +  +L     
Sbjct: 369 IGVVGRIGQKILREHLKKYEDTFRVIIMHHNITPIPKS-REIGFLEDGGNVLKILTD-EK 426

Query: 196 VKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHAD 251
              +L GH    L +      ++   S              +     +  ++++ D
Sbjct: 427 ANLVLTGHGGNSLGMKIEQTPIVNAGSISW-------ELHRNPFGNSFNLIDIYED 475


>UniRef50_B5JAZ3 Ser/Thr protein phosphatase family protein n=2 Tax=Rhodobacteraceae
           RepID=B5JAZ3_9RHOB
          Length = 274

 Score =  203 bits (517), Expect = 6e-51,   Method: Composition-based stats.
 Identities = 65/267 (24%), Positives = 106/267 (39%), Gaps = 14/267 (5%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           +IL +TD HL     + ++G++     Q  L+A      +   ++  GDL     +  Y 
Sbjct: 3   KILVLTDLHLRGAG-KTIIGLDPTARLQQALDAALGDHPDARALILMGDLTHSGRAEEYD 61

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISP---AKRVFIGEQWQILLLDSQVF 132
              + +     P  ++ GNHD +    +A  +A ++P    +R+      +I+ LD+   
Sbjct: 62  KLRDLLHDCPIPVTYMLGNHDQRTRFCAAFPEATVTPQGHVQRIIDLAHHRIITLDTHDA 121

Query: 133 G---VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
                  G L   +L WL+  LA A  R  L+  HH P P G   +D  +L N  EL   
Sbjct: 122 AANPAHSGRLCAGRLAWLDAALAGAGGRMALVFAHHPPHPVGLPGMDAIALVNGDELLDR 181

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHC----SNFTLDTIAPGWRT 245
           L   P   +L CGH+H+ +     G       STC Q         S  ++D  A  +  
Sbjct: 182 LRAAP--AHLFCGHVHRTISGQARGVAFTMFKSTCHQAPLDLLRPDSTLSIDEPA-AYGL 238

Query: 246 LELHADGTLTTEVHRLADTRFQPDTAS 272
           L L   G +            + D  +
Sbjct: 239 LLLTKGGVIAHSEDIALGLTPRSDLDA 265


>UniRef50_Q3AIR5 Possible ICC (3',5'-cyclic-nucleotide phosphodiesterase) protein
           n=4 Tax=Chroococcales RepID=Q3AIR5_SYNSC
          Length = 253

 Score =  203 bits (516), Expect = 6e-51,   Method: Composition-based stats.
 Identities = 75/252 (29%), Positives = 114/252 (45%), Gaps = 9/252 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +RILQ++D HL A     + G      ++  L+       +  L++ TGDL QD+S   Y
Sbjct: 1   MRILQLSDPHLVAADQGLVRGRPALAHFERALQLGGALNPD--LVLVTGDLCQDESWGGY 58

Query: 75  QHFAEGIAS-FRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFG 133
                 ++   R     LPGNHD  P +  A+     + A    + +  ++LLL S   G
Sbjct: 59  ARLRRALSQHVRCSVALLPGNHDH-PLLLDAVLGRRWTTAPADLLVQGVRVLLLSSHQVG 117

Query: 134 VPHGELSEFQLEWLERKLADAP--ERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
              G L   QL+WLE++L  +   +   ++ LHH P+  G + +D   L +   L+ +L 
Sbjct: 118 SAAGALGSLQLQWLEQRLRCSERLDLPLVVALHHPPIAIGDAGMDAIRLLDQACLEALLR 177

Query: 192 KFPHVKYLLCGHIHQELDLDWN---GRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLEL 248
               ++ +L GHIHQ     W+      LL  PST   FK            PG R +EL
Sbjct: 178 PHRALRAVLFGHIHQHWQGSWSTRPDVLLLGCPSTLCSFKAVQPCPLGRADDPGGRLVEL 237

Query: 249 HADGTLTTEVHR 260
            ADG +   V R
Sbjct: 238 TADGAIQHRVLR 249


>UniRef50_A4F6Q6 Cyclic nucleotide phosphodiesterase n=7 Tax=Actinomycetales
           RepID=A4F6Q6_SACEN
          Length = 255

 Score =  203 bits (516), Expect = 7e-51,   Method: Composition-based stats.
 Identities = 63/240 (26%), Positives = 98/240 (40%), Gaps = 9/240 (3%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
            + I  ++D H          G  + E  +  L+ +R      D +V TGD+A       
Sbjct: 2   TMAIAHLSDPH----TTTGAQGDESVERLRRGLDCVRALDRLPDCVVITGDVADGGHRQE 57

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDA----GISPAKRVFIGEQWQILLLDS 129
           Y+     IA F  P     GNHD    +           G   A+       + ++ LDS
Sbjct: 58  YEAVRAVIADFPVPVHLTTGNHDDPRGLAEVFGGTDVLGGAREARYAVDYPGFTLVALDS 117

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
            + G P G L   QL WL+  LA  P+   ++ +HH P+  G  +LD   + +A E   V
Sbjct: 118 HMPGSPGGRLGADQLAWLDDVLARRPDVPAVVCVHHPPVAVGIPYLDGMGMEDAAEFAGV 177

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHC-SNFTLDTIAPGWRTLEL 248
           +A+  +V  +L GH+H+ +  D+ G  L   PST +Q       +       P    L L
Sbjct: 178 IARHRNVARVLAGHVHRAVVADFAGATLTTAPSTHIQIGFTTGEDVPPLHADPASFLLHL 237


>UniRef50_B0P519 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=B0P519_9CLOT
          Length = 305

 Score =  202 bits (515), Expect = 8e-51,   Method: Composition-based stats.
 Identities = 51/224 (22%), Positives = 94/224 (41%), Gaps = 10/224 (4%)

Query: 13  ARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQH--EFDLIVATGDLAQDQS 70
           A ++++QI+D HL      +    +T ++    ++     +     +  V TGDL++  +
Sbjct: 13  AFMKVIQISDFHLRGDGKLSFQKADTMKALHQTIDYFCSMKDYELPEFFVVTGDLSEGGT 72

Query: 71  SAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGI------SPAKRVFIGEQWQI 124
              Y+   EG+     P   +PGNHD +        +                     ++
Sbjct: 73  REGYEFMREGLRKLPRPVYIVPGNHDKRDFFLEMFTEETPVKEDIKPYICYTIDEYPVRV 132

Query: 125 LLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAG 184
           +++D+       G LS+   EWLE ++ + PE+ TL+  HH P   G   +D+     A 
Sbjct: 133 IVIDTSKPSCHSGGLSDRVAEWLEERITEYPEKPTLVFTHHPPFVTGLPAMDE-GFDQAD 191

Query: 185 ELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFK 228
            L  +L K  +V  L CGH+H  +   W+    +  P   +Q +
Sbjct: 192 RLAQILNKHENVT-LCCGHMHTAIFTSWHKIPCVTCPPIAMQME 234


>UniRef50_A6U5M4 Metallophosphoesterase n=3 Tax=Rhizobiaceae RepID=A6U5M4_SINMW
          Length = 268

 Score =  202 bits (514), Expect = 1e-50,   Method: Composition-based stats.
 Identities = 51/255 (20%), Positives = 102/255 (40%), Gaps = 15/255 (5%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           +++  +D H+  +    ++G++        +  +     + DL++  GDLA      +Y+
Sbjct: 3   KLIIFSDLHMVPEGG-TIIGLDPHRRLANGIAHVNRFHADADLVIFAGDLAHAADRESYE 61

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV---FIGEQWQILLLDSQV- 131
                +     P   + GNHD +        +A       V         + +LLD+   
Sbjct: 62  RLQALLRELMPPAALMIGNHDRRELFLDVFAEAVTDANGFVQQAIDFPDCRAILLDTLFA 121

Query: 132 -----FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGEL 186
                     G L + +L WL+R+L +A +R  L+ +HH P  +G + +D   L N  E 
Sbjct: 122 PPYDYPVSHAGHLCQTRLAWLDRQLGEAGDRPALIFMHHPPHASGFAGMDMIRLVNEDEF 181

Query: 187 DTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQ----FKPHCSNFTLDTIAPG 242
             ++ +  +V+++  GH+H+ +     G       S   Q    F    ++ ++D  A  
Sbjct: 182 YALVKRHGNVRHIFAGHVHRTISGSSRGIPFSIFKSPVHQQPMPFATADASLSVDEPA-A 240

Query: 243 WRTLELHADGTLTTE 257
           +    +  DG L   
Sbjct: 241 YGIALVTPDGVLVHT 255


>UniRef50_C6BIA6 Metallophosphoesterase n=2 Tax=Ralstonia pickettii
           RepID=C6BIA6_RALP1
          Length = 284

 Score =  202 bits (514), Expect = 1e-50,   Method: Composition-based stats.
 Identities = 59/246 (23%), Positives = 98/246 (39%), Gaps = 18/246 (7%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
            +  LQ+TD H+      A   V++       +  I     + D IV TGDL    +   
Sbjct: 2   PMHFLQLTDLHIKRPGRLAYRRVDSAAYLARCVAHILAQPEKPDAIVLTGDLVDAGAPEE 61

Query: 74  YQHFAEGIASFR---APCVWLPGNHDFQPAMYSALQD-----AGISPAKRVF----IGEQ 121
           Y H    +A         + + GNHD + A   A  D        +   R F        
Sbjct: 62  YAHLRAVLAPLDAAGIHMLPVLGNHDGRDAAREAFVDWLAPIPADAQDTRAFQYWTDIGD 121

Query: 122 WQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL- 180
            +++++D+   G P G L   +L+WL   LA   +R T++ +HH P   G   +D  SL 
Sbjct: 122 VRLIVIDTLDTGHPGGRLGVQRLDWLAEALAHETQRPTVIAMHHPPFATGIGHMDVQSLA 181

Query: 181 -RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTI 239
             +      ++    +V+ ++CGH+H+ +D+ + G      PS   Q             
Sbjct: 182 PEDIPAFAQIVRAAGNVERIICGHLHRSIDVRFAGTVASTCPSPAHQVALDLDP----NA 237

Query: 240 APGWRT 245
           APG+  
Sbjct: 238 APGFVM 243


>UniRef50_A0NQD3 Ser/Thr protein phosphatase family protein n=1 Tax=Labrenzia
           aggregata IAM 12614 RepID=A0NQD3_9RHOB
          Length = 272

 Score =  201 bits (513), Expect = 2e-50,   Method: Composition-based stats.
 Identities = 54/214 (25%), Positives = 92/214 (42%), Gaps = 7/214 (3%)

Query: 20  ITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAE 79
           +TD HL  +        +T    +  + +++    + D +V TGD+        Y     
Sbjct: 1   MTDLHLRPRGLACYRVSDTNMLAERAIRSLQSLTPKPDALVITGDITDGNDPREYALARS 60

Query: 80  GIASFRAPCVWLPGNHDFQPAMYSALQDAG------ISPAKRVFIGEQWQILLLDSQVFG 133
            ++    P   +PGNHD    M   L                       +++ LD+ + G
Sbjct: 61  ILSRVDMPVFLVPGNHDGTQVMRRELAGFPGLAGSLDDKICYTADIADIRLIALDTHIPG 120

Query: 134 VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKF 193
            P G L + QL+WL+ +L ++  + TL+ LHH P  +G   +D   L +A  L  V++  
Sbjct: 121 DPRGRLGQAQLDWLDGQLKES-SKTTLIALHHPPALSGIRHMDDIGLVDADALAEVVSPH 179

Query: 194 PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQF 227
            HV   LCGH+H+ +   + G+ +   PST  Q 
Sbjct: 180 RHVARFLCGHLHRPIIASFAGKVMTLAPSTGHQV 213


>UniRef50_B7QYI4 3',5'-cyclic-nucleotide phosphodiesterase, CpdA n=1 Tax=Ruegeria
           sp. R11 RepID=B7QYI4_9RHOB
          Length = 275

 Score =  201 bits (512), Expect = 2e-50,   Method: Composition-based stats.
 Identities = 55/238 (23%), Positives = 96/238 (40%), Gaps = 5/238 (2%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
            ++++ ++D H   Q    +LG +      A ++ I  H  +    V +GD+A+  ++  
Sbjct: 10  SMKLIWMSDLHF--QHSGEILGHDPQLRLDAAIDYINQHHSDASYCVISGDMAETATARN 67

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAG---ISPAKRVFIGEQWQILLLDSQ 130
           Y   A+ +     PC+ + GNHD +  + +  Q          +         IL LD+ 
Sbjct: 68  YADLADRLDQLAIPCLPMVGNHDDRDLLRAQFQVPDSCMDGFLQYSVDTPAGLILCLDTL 127

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
             G   GE    +  WL   L  A +R  LL LHH P+P G    D   L +      ++
Sbjct: 128 KPGASEGEFCAERARWLTSTLDAAQDRAVLLFLHHPPMPLGLPVQDSARLEHGARFLEII 187

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLEL 248
               ++++L  GH+H+ +     G    A  S   Q  P    +  ++  P     EL
Sbjct: 188 EGRANLRHLCVGHVHRSVTGTIRGIPFTALRSVLYQAPPPQPEWDWNSFTPSAEAPEL 245


>UniRef50_C7S9W5 Protein icc n=17 Tax=Bacteria RepID=C7S9W5_ECOLX
          Length = 274

 Score =  200 bits (510), Expect = 3e-50,   Method: Composition-based stats.
 Identities = 51/225 (22%), Positives = 97/225 (43%), Gaps = 7/225 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + +  I+DTH  ++  +    ++   +   V+  +   +   D +V +GD+        Y
Sbjct: 1   MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALRERPDAVVVSGDIVNCGRPEEY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQ----DAGISPAKRVFIGEQW--QILLLD 128
           Q   + + S   P   +PGNHD +      L       G  P    ++ + +  ++L +D
Sbjct: 61  QVARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDPQNMRYVVDDFATRLLFID 120

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           S   G   G L++  + WLE +L +  ++   + +HH PLP G + +D  +  N   L  
Sbjct: 121 SSHAGTSKGWLTDETIGWLEAQLFEGGDKPATIFMHHPPLPLGNAQMDPIACENGHRLLE 180

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSN 233
           ++ +FP +  + CGH H      +    +   P T  Q  P+C  
Sbjct: 181 LVERFPSLTRIFCGHNHSLTITQYLQALISTIPGTVHQV-PYCHE 224


>UniRef50_B3Q702 Metallophosphoesterase n=5 Tax=Alphaproteobacteria
           RepID=B3Q702_RHOPT
          Length = 274

 Score =  200 bits (510), Expect = 3e-50,   Method: Composition-based stats.
 Identities = 53/218 (24%), Positives = 93/218 (42%), Gaps = 5/218 (2%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++++ ++D HL       + G N   +++  L  I    H+ +L+V TGDL+    +  Y
Sbjct: 1   MKLIHLSDIHLTTPG-GTIGGRNPRLNFERALTHILRDHHDAELMVITGDLSDWGDAEDY 59

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQD--AGISPAKRVFIGEQWQILLLDSQVF 132
           +     + +F  P     GNHD +    S   +        + V      + LLLD+   
Sbjct: 60  RWLKAQLGAFPIPVRLCIGNHDRRENFLSVFPEFADDDGLVQGVCDTPAGRCLLLDTAEA 119

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
           G   G   E +  WL R+LA+ P    LL +HH+P+P     +DQ  L + G    ++ +
Sbjct: 120 GTHAGRYCETRRAWLTRQLAEHPG-PFLLFMHHNPMPTHLGPMDQIRLLDDGAFGQIVGR 178

Query: 193 F-PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKP 229
               ++++  GH H  L     G  + +   T     P
Sbjct: 179 HRDRIRHIFFGHCHLPLAGSVAGVPVSSLRGTNHASYP 216


>UniRef50_Q0FF25 Putative uncharacterized protein n=1 Tax=Rhodobacterales bacterium
           HTCC2255 RepID=Q0FF25_9RHOB
          Length = 275

 Score =  200 bits (509), Expect = 4e-50,   Method: Composition-based stats.
 Identities = 48/220 (21%), Positives = 99/220 (45%), Gaps = 9/220 (4%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           ++L I+D HL ++K   ++G++    +   L        + + ++  GD+      + Y+
Sbjct: 3   KVLVISDIHLRSKKRN-IIGLDPLRQFTEALSHALKKHPDAEHMILIGDMTHSGHVSEYE 61

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV---FIGEQWQILLLDS--- 129
                  +++ P  ++ GNHD +        +  +     +          ++ LD+   
Sbjct: 62  MLKRATNTYKIPITFMLGNHDNRSNFKKVFPEIPLDNEGYLQKKISLGDDVLICLDTLNS 121

Query: 130 --QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELD 187
             Q+     G+L E +LEWLE++L+ A  +   +  HH P   G   +D+  L N+ +L 
Sbjct: 122 SPQLEIEHEGKLCEKRLEWLEQELSQAKNKRISIFTHHPPHNIGFPGMDKIKLSNSADLF 181

Query: 188 TVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQF 227
            ++ K+ + K++  GH+H+ +  + NG       STC Q 
Sbjct: 182 NIIKKYKNTKHIFSGHVHRSISGNTNGIGFTIFKSTCHQM 221


>UniRef50_A4EJU5 3',5'-cyclic-nucleotide phosphodiesterase, cpdA n=2
           Tax=Rhodobacterales RepID=A4EJU5_9RHOB
          Length = 262

 Score =  200 bits (509), Expect = 5e-50,   Method: Composition-based stats.
 Identities = 55/247 (22%), Positives = 96/247 (38%), Gaps = 10/247 (4%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           +I+ ++D H   Q    + G++     +A +  +  H  + D  V TGDL  D     Y 
Sbjct: 3   KIIWMSDPHF--QMTGTIDGLDPRVRLKAAITYLNTHYTDADFAVLTGDLVGDDIVEDYT 60

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQ---DAGISPAKRVFIGEQWQILLLDSQVF 132
             AE +A  +     L GN+D + +  + L    D      + V        + LD+   
Sbjct: 61  GIAEYLAKSQVSIYPLMGNNDERESFRAHLPLPADGMPDFIQYVVDTPDQTFICLDTHKV 120

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
           G   G+    +  WL++ LA  P +   + +HH PL  G    D+  L ++     +++ 
Sbjct: 121 GSHAGQFCSARQAWLDQVLAKDPLKPAYIFMHHPPLNLGLPPQDEIMLEDSDAFLDIVSA 180

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCS-----NFTLDTIAPGWRTLE 247
             +VK+L  GH+H+       G       +   Q           +F L   AP    L 
Sbjct: 181 HNNVKHLFMGHVHRPTAGTVKGIPFATIGALSFQAPAPQPAWHWDSFVLAKEAPQLGVLL 240

Query: 248 LHADGTL 254
           +  D  +
Sbjct: 241 IENDKVV 247


>UniRef50_Q1GWA3 Metallophosphoesterase n=1 Tax=Sphingopyxis alaskensis
           RepID=Q1GWA3_SPHAL
          Length = 282

 Score =  200 bits (508), Expect = 6e-50,   Method: Composition-based stats.
 Identities = 55/216 (25%), Positives = 97/216 (44%), Gaps = 5/216 (2%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + I QITD H+              +    VL+ +    +  DL++ATGD+     + +Y
Sbjct: 1   MLIAQITDIHIGFDPDNPAE--YNRKRLDEVLDVLIEGPNRPDLLLATGDITDRGDADSY 58

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQ--DAGISPAKRVFIGEQWQILLLDSQVF 132
           +  A   +    P     GNHD +   ++     D G    +      + +++ +D+   
Sbjct: 59  RRLATAFSRCPFPVWPSVGNHDLRDNFHARFPGFDDGNGFVQYTVELPELRLVTIDTLEE 118

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGE-LDTVLA 191
           G   G   E +  WL+ +LA AP R T +++HH P+ +G  W++ H           V+ 
Sbjct: 119 GRHGGAFCERRAAWLDAELAKAPARPTYIVMHHPPVESGIEWMNTHPDEPWVATFTDVVR 178

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQF 227
           + P V+ L+CGH+H+ + + W GR +    ST  Q 
Sbjct: 179 RHPQVRGLICGHLHRSVTVAWEGRTIAICSSTAPQV 214


>UniRef50_A3WHQ7 Putative cAMP phosphodiesterase n=1 Tax=Erythrobacter sp. NAP1
           RepID=A3WHQ7_9SPHN
          Length = 294

 Score =  199 bits (506), Expect = 9e-50,   Method: Composition-based stats.
 Identities = 60/264 (22%), Positives = 101/264 (38%), Gaps = 17/264 (6%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
           + +  V I QITDTH+  +        N +  ++ VL  +   +   D+++ +GDL    
Sbjct: 3   SEKRGVLIAQITDTHVGFEPEAGENEFN-FVRFRNVLGHLLNQKILPDMLILSGDLTDGG 61

Query: 70  SSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVF-------IGEQW 122
              +Y    E +A    P   +PGNHD +  +  A  D   +     F        G   
Sbjct: 62  QPDSYARIRELVAECPFPVHVIPGNHDSRDELLKAFPDCPTADGFAQFAIDCDDGAGNAL 121

Query: 123 QILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRN 182
           ++L LDS   G   G   E +  WL ++LA  P+  T++ +HH P+ AG  W+D      
Sbjct: 122 RVLCLDSFEPGRHGGAFCEVRAAWLAKELAAHPDTPTVIFMHHPPVVAGIDWMDPKPGEA 181

Query: 183 A-GELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQF--------KPHCSN 233
                   +     +  +  GH+H+ L     G  L  TP+                  +
Sbjct: 182 WFKRFHDTVKGHDQIISIQAGHLHRPLHSVVEGIPLSVTPAVAPAVALDLRPMDAEVADS 241

Query: 234 FTLDTIAPGWRTLELHADGTLTTE 257
             +    P + +L L   G   + 
Sbjct: 242 RPIVAAEPPFYSLHLWRGGEFVSH 265


>UniRef50_Q982B7 Mll9148 protein n=1 Tax=Mesorhizobium loti RepID=Q982B7_RHILO
          Length = 325

 Score =  199 bits (506), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 62/258 (24%), Positives = 94/258 (36%), Gaps = 7/258 (2%)

Query: 14  RVRILQITDTHLFAQKHEALLG-VNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA 72
            + I  ++D H+         G V+         E +       D++V TGDLA      
Sbjct: 40  SMIIAHLSDLHIRETGKPFASGNVDCTARAAQAFERVANMTPRPDMMVVTGDLADSGQIG 99

Query: 73  AYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDA--GISPAKRVFIGEQWQILLLDSQ 130
            YQ   E       P     GNHD +    +   +        +     ++ +++ LD+ 
Sbjct: 100 EYQLLKELTEGLPFPVHLALGNHDIRENFLAVFPEKKGPGGFVQFCVEHDKLRVIGLDTL 159

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRN-AGELDTV 189
           V G   G L   +L +L   L + P   TL+LLHH P   G    D   L + A EL  +
Sbjct: 160 VEGEGLGRLCSERLSYLRDCLQERPNTSTLILLHHPPFAFGGGIYDAVRLIDGARELGEI 219

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPST---CVQFKPHCSNFTLDTIAPGWRTL 246
           +     V  LLCGH H+ +D  WNG      PS    C         F      P ++  
Sbjct: 220 ITANKQVVRLLCGHHHRAIDCLWNGTLASVAPSVVSSCHLQLGDVRVFKNINEPPAFKLH 279

Query: 247 ELHADGTLTTEVHRLADT 264
            L  +    +    + D 
Sbjct: 280 VLVPESGFVSHNVFVEDF 297


>UniRef50_A5GLK1 Predicted phosphohydrolase n=4 Tax=Synechococcus RepID=A5GLK1_SYNPW
          Length = 265

 Score =  198 bits (503), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 71/257 (27%), Positives = 113/257 (43%), Gaps = 15/257 (5%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           R++Q++D HL A+    + G +    +Q  L      Q +  L++ TGD   D++   Y 
Sbjct: 3   RLIQLSDPHLVARAEGRVRGRSALSLFQKALAQALQEQPD--LLLVTGDCCHDETWCGYV 60

Query: 76  HFAEGIASF----RAPCVWL---PGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLD 128
              + + +      A  V L    GNHD    + + L       A  V     W++L++ 
Sbjct: 61  RLRDAVDAAIQQQAARTVCLGFTAGNHDHPQRLRAVL-GRHWVVAPGVMDAGCWRLLVVS 119

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAP--ERHTLLLLHHHPLPAGCSWLDQHSLRNAGEL 186
           S   G   G +   QL WL  +L +A    +  ++ LHH P+P G + +D   L +  +L
Sbjct: 120 SHRAGGCAGVIGGVQLSWLNTQLREAETLGKFVVVALHHPPVPIGDASMDTIGLSDGEQL 179

Query: 187 DTVLAKFPHVKYLLCGHIHQELDLD---WNGRRLLATPSTCVQFKPHCSNFTLDTIAPGW 243
              L ++P V+ +L GHIHQ         +   LL  PST V F P           PG 
Sbjct: 180 MDSLKRWPAVRVVLFGHIHQHWKGMAAPRSDLSLLGCPSTLVSFHPVQPCPLGRAWDPGG 239

Query: 244 RTLELHADGTLTTEVHR 260
           R L+L  DG++   + R
Sbjct: 240 RLLDLMEDGSVQERLMR 256


>UniRef50_B4RZD1 3,5-cyclic-nucleotide phosphodiesterase n=2 Tax=Alteromonas
           macleodii RepID=B4RZD1_ALTMD
          Length = 267

 Score =  196 bits (499), Expect = 6e-49,   Method: Composition-based stats.
 Identities = 70/269 (26%), Positives = 128/269 (47%), Gaps = 23/269 (8%)

Query: 15  VRILQITDTHLFAQKHEA-LLGVNTWESYQAVLEAIRPHQHEFD----------LIVATG 63
           ++++Q++D HL   K+E    G+  ++S +  L     H  +F+           ++ TG
Sbjct: 2   IKLIQLSDCHLLKDKNETGYAGIAPYDSLERTLLHAVNHAEQFEANNSSMAPSCFMLITG 61

Query: 64  DLAQDQSSAAYQHFAEGIASF----RAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIG 119
           D++ D +  +YQHF   +  +          L GNHD      + L D  ++ +      
Sbjct: 62  DISGDNTPESYQHFIALMDKYVDRANIAWFVLAGNHDNNAHFETYLGDKQLN-SDNPLTF 120

Query: 120 EQWQILLLDSQVFGVPH---GELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLD 176
           + W I  +D++     +   GE+   ++  L + +A  P+ + L+ LHHH LP+   W+D
Sbjct: 121 QNWHIHGMDTRALDSTYTAAGEVKGGEIHDLTQAVAQLPDNNHLIALHHHILPSNS-WMD 179

Query: 177 QHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDW--NGRRLLATPSTCVQFKPHCSNF 234
           +H L NA  L ++  ++  +K L+ GH+H  L      N       PSTC Q++   + F
Sbjct: 180 KHFLANAEALVSLTEQYAQIKALIHGHVHSPLRQLIGENSTPSYGCPSTCWQWEMQLA-F 238

Query: 235 TLDTIAPGWRTLELHADGTLTTEVHRLAD 263
            +   APG++ +ELH DG +   + R+  
Sbjct: 239 GVSNDAPGYQVIELHEDGVVDVSIERVEH 267


>UniRef50_A4AIJ2 Putative uncharacterized protein n=1 Tax=marine actinobacterium
           PHSC20C1 RepID=A4AIJ2_9ACTN
          Length = 305

 Score =  196 bits (499), Expect = 6e-49,   Method: Composition-based stats.
 Identities = 62/250 (24%), Positives = 103/250 (41%), Gaps = 9/250 (3%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           +L ++DTH  A        +++    + +   +       + IV TGDLA      AY+ 
Sbjct: 15  VLHLSDTHFLAGSGRLYDTLDSEAKLRQLFAELEASGSRPEAIVFTGDLADKGDEVAYRE 74

Query: 77  FAEGIA----SFRAPCVWLPGNHDFQPAMYSALQDAGIS--PAKRVFIGEQWQILLLDSQ 130
               +        A  VW+ GNHD +    + L D   S  P  RV      +I+ LDS 
Sbjct: 75  IRAIVEPAAERLGAHIVWVMGNHDDRRNFATTLLDEPASEQPIDRVTDINGLRIISLDST 134

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
           V G  HG +++ QL WL   LA      T+L +HH P+P+         LR+  EL  V+
Sbjct: 135 VPGQHHGHVTDAQLLWLHNVLATPAPHGTILAMHHPPVPSVLDLAVTVELRSQKELAAVI 194

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTL--DTIAPGWRTLEL 248
            +   ++ ++ GH+H      + G  +    +TC     +           A  +  + +
Sbjct: 195 -RGSDIRSIIAGHLHYSTTATFAGIPVSVASATCYTQNLNVPVGGTRSQDGAQSFNLIHV 253

Query: 249 HADGTLTTEV 258
           + D  L + V
Sbjct: 254 YDDTVLHSVV 263


>UniRef50_D1XS68 Metallophosphoesterase n=1 Tax=Streptomyces sp. ACTE
           RepID=D1XS68_9ACTO
          Length = 262

 Score =  196 bits (498), Expect = 8e-49,   Method: Composition-based stats.
 Identities = 67/264 (25%), Positives = 99/264 (37%), Gaps = 28/264 (10%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           +  ++D HL   +  A                        D ++ TGD+    ++  Y  
Sbjct: 4   LAHLSDPHLDGTEESAARAHRAVAHLA-------GLPGRVDAVLITGDIVDRGTAEEYHQ 56

Query: 77  FAEGIASF--RAPCVWLPGNHDFQPAMYSAL---------------QDAGISPAKRVFIG 119
             E +A    R   +  PGNHD +      L                  G +P   V   
Sbjct: 57  AREVLAPLYERHEVLLCPGNHDSRAPYREVLLGGGGGGSGSGGGDDGGGGTAPVNEVRDV 116

Query: 120 EQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHS 179
              ++L+ DS V G P G L    L WL+  LA AP+R   + LHH P+P G  ++D+  
Sbjct: 117 GGVRVLMCDSSVPGRPEGLLEAATLSWLDDALAAAPDRPAFVALHHPPVPLGLPYIDRIG 176

Query: 180 LRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTC----VQFKPHCSNFT 235
           LR    L  VLA+   V  +LCGH H      + G  LL  P       + ++       
Sbjct: 177 LREPDALAKVLARHAQVVAVLCGHAHTAAATSFAGLPLLCAPGIASTALLPWEQGPDASW 236

Query: 236 LDTIAPGWRTLELHADGTLTTEVH 259
               AP      L+ +G LT+ V 
Sbjct: 237 KTHGAPPALAFHLYEEGRLTSHVR 260


>UniRef50_B5J8T8 Ser/Thr protein phosphatase family protein n=2 Tax=Rhodobacteraceae
           RepID=B5J8T8_9RHOB
          Length = 259

 Score =  196 bits (498), Expect = 9e-49,   Method: Composition-based stats.
 Identities = 60/258 (23%), Positives = 108/258 (41%), Gaps = 10/258 (3%)

Query: 15  VRILQITDTHLFAQKHEA-LLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
           + I  I+D H+FA+  E  L+  +  ++ + V+  I     +   ++ TGDL    S+  
Sbjct: 1   MLIAHISDFHIFAEAPETSLVRPDAADAARKVVADIAAFTPQIGAVMFTGDLTDGGSAED 60

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQW----QILLLDS 129
           Y    + ++    P   +PGNHD +P M ++        A      E W    +IL LD+
Sbjct: 61  YALLTDILSPLDVPVFVVPGNHDARPGMRASFAGKLPFEADPFLNYEAWFNDIRILALDT 120

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNA-GELDT 188
              G   G L + QL WL  +LA      TL+L+HH   P+  + LD  +L++   + + 
Sbjct: 121 LWDGQIAGRLDQTQLVWLAERLAVPHHGLTLILMHHPAFPSQMAPLDAMTLQDGRADFER 180

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQ----FKPHCSNFTLDTIAPGWR 244
           ++A +     +L GHIH+     W+G     +     Q      P      +      + 
Sbjct: 181 LIANYNEPLRILSGHIHRPFQTLWHGVFCAVSGGPAFQHALTLDPDADEPGIVAEPYAYF 240

Query: 245 TLELHADGTLTTEVHRLA 262
              +    +++     +A
Sbjct: 241 IHRITDATSVSIHTRYVA 258


>UniRef50_B6IT97 Phosphodiesterase, putative n=1 Tax=Rhodospirillum centenum SW
           RepID=B6IT97_RHOCS
          Length = 265

 Score =  195 bits (496), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 75/260 (28%), Positives = 115/260 (44%), Gaps = 10/260 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + I Q+TD H+ A+   A   V+T ++    +  +       DL+V TGD+        Y
Sbjct: 1   MLIAQLTDLHVTARGARAFGEVDTNDALARAVAHVAALPRRPDLVVVTGDVVNGPQPGEY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQ--DAGISPAKRVF---IGEQWQILLLDS 129
              AE +A    P + +PGNHD +  + +AL+  D G+     +         +IL LD+
Sbjct: 61  AMAAELLAGLGLPLLVIPGNHDDREELRTALRPLDPGLPDGPYLHRMMDTGPLRILALDT 120

Query: 130 QVFGVPHGELSEFQLEWLERKLADAP-ERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
            V G P G L   +L W+  +LA+AP ER  L+L+HH P  +G   +D+ +   A  L  
Sbjct: 121 VVPGRPEGALDAPRLAWIADRLAEAPHERPLLVLMHHPPFVSGIGHMDRMNCAGADALAG 180

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCV--QFKPHCSNFTLDTIAPGWRTL 246
           +L     V  LLCGH+H+ +   W G      P+T           +    T  P    L
Sbjct: 181 LLRGRT-VAGLLCGHVHRPIAAHWRGIPCFCGPATAHLVALDLEPESPARWTREPPAVAL 239

Query: 247 ELHADGT-LTTEVHRLADTR 265
            L  D   L T +  + D  
Sbjct: 240 HLWDDAHGLRTHLSFIGDFP 259


>UniRef50_A5CN72 Putative 3',5'-cyclic-nucleotide phosphodiesterase n=2
           Tax=Clavibacter michiganensis RepID=A5CN72_CLAM3
          Length = 301

 Score =  195 bits (495), Expect = 2e-48,   Method: Composition-based stats.
 Identities = 73/275 (26%), Positives = 119/275 (43%), Gaps = 26/275 (9%)

Query: 12  EARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
              +R++ ++DTHL          V+T  + + VL        E  L+V +GDL++D ++
Sbjct: 6   PGSLRLVHLSDTHLLRDGGLHQGVVDTGAALERVLVEA-DRVPEVRLLVGSGDLSEDGTA 64

Query: 72  AAYQHFAEGIASF----RAPCVWLPGNHDFQPAMYSALQD-------------AGISPAK 114
            +Y    E +  +     A  V  PGNHD + A    L D             A + P  
Sbjct: 65  ESYALLRERLVPWTSSRGAALVLTPGNHDVRSAFRLVLGDGHGAPGTDDGRDPAAVPPVD 124

Query: 115 RVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSW 174
            V I + W+I  LD+ V G  +G L E QL+ L   LA   E  T+L+LHH P+PA  + 
Sbjct: 125 GVTIVDGWRIATLDTSVPGKGYGALREQQLDGLRELLATPAEHGTVLVLHHPPVPAPTTL 184

Query: 175 LDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTC----VQFKPH 230
            +  +L+    L  ++ +   V+ +L GH H  +     G  +L  P       V  +P 
Sbjct: 185 HESLALQGPERLAEIV-RGSDVRVILSGHYHHHIVGSLAGVPVLVAPGVANETDVAAEPG 243

Query: 231 CSNFTLDTIAPGWRTLELHADGTLTTEVHRLADTR 265
                  +   G+  +++  DG +T+ V R     
Sbjct: 244 TERIVRGS---GFLVVDVRPDGRVTSVVVRAHAED 275


>UniRef50_A9CKB5 Putative uncharacterized protein n=2 Tax=Alphaproteobacteria
           RepID=A9CKB5_AGRT5
          Length = 266

 Score =  194 bits (494), Expect = 2e-48,   Method: Composition-based stats.
 Identities = 60/241 (24%), Positives = 100/241 (41%), Gaps = 8/241 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++I+QITDTHL      A+ GV+     +A +  I     + DL+V TGDL       AY
Sbjct: 1   MKIIQITDTHLLPPG-IAINGVDPENQLRAAVADIVEKHADADLLVMTGDLCNYGEPEAY 59

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV---FIGEQWQILLLDSQV 131
           +   + +A    P   + GNHD +P   +A  +        +      E  ++L LDS  
Sbjct: 60  ELLRDILAPVSIPTRLMLGNHDRRPEFVAAFPEQPRDDNGYIQSFIDTEFGRLLFLDSHE 119

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
             V  G     +L WLE  L  A +    + +HH P+  G    +   + + G +   LA
Sbjct: 120 ADVIGGIYGADRLTWLENALESAGDLPITVFVHHPPMDCGIRHFEHIGMHDDGAIMRRLA 179

Query: 192 KFP-HVKYLLCGHIHQELDLDWN-GRRLLATPSTCVQF--KPHCSNFTLDTIAPGWRTLE 247
             P  +++++ GHIH  +      G    +  +   +F       +       P +R + 
Sbjct: 180 AHPAGIRHIVFGHIHVPMAGTTAEGIAYSSGQACAHRFITDIDVVDPLWTGGNPCYRVIS 239

Query: 248 L 248
           L
Sbjct: 240 L 240


>UniRef50_UPI0001B53F99 metallophosphoesterase n=1 Tax=Streptomyces sp. AA4
           RepID=UPI0001B53F99
          Length = 253

 Score =  194 bits (493), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 68/259 (26%), Positives = 101/259 (38%), Gaps = 21/259 (8%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
              ++D HL   +              AV   +R  +   D + ATGDLA       Y+ 
Sbjct: 4   FAHLSDIHLDGSERAD-------ARAAAVTRYLRNLEKPVDAVFATGDLADHGLPGEYRR 56

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSAL--QDAGISPAKRVFIGEQWQILLLDSQVFGV 134
            AE +     P V  PGNHD +     AL  + A  +P        +  ++  DS + G 
Sbjct: 57  AAELL-DLPVPVVVCPGNHDVRAPFREALLGEPASDAPVNTATKVAEVLLVSCDSTIPGK 115

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
             G L++  L WL+  LA   +  + +  HH PL  G   +D         L  VL + P
Sbjct: 116 GAGYLADETLAWLDETLAAH-DGPSFVAFHHPPLDVGVPLVDAIRQTGEDRLAAVLKRHP 174

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPST----CVQFKPHC-----SNFTLDTIAPGWRT 245
            V  LLCGH+H     ++ G  +   P       +  +P           LD ++P    
Sbjct: 175 GVAALLCGHVHTGAATEFAGVPVRIAPGVVSGSLLPVEPGAGRGWDEGGPLDFVSPPSLL 234

Query: 246 LE-LHADGTLTTEVHRLAD 263
           L  LH DG LTT    + +
Sbjct: 235 LHVLHDDGRLTTHQRAVTE 253


>UniRef50_Q2RNL1 Metallophosphoesterase n=1 Tax=Rhodospirillum rubrum ATCC 11170
           RepID=Q2RNL1_RHORT
          Length = 283

 Score =  194 bits (493), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 64/229 (27%), Positives = 97/229 (42%), Gaps = 15/229 (6%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + I Q +D H+          V+T  + +A +  ++   H  DL++ TGDL Q      Y
Sbjct: 1   MLIAQTSDLHIRPPGMLVGGVVDTAAALEACVAHLQALAHRPDLLLITGDLTQQGRPEEY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISP------------AKRVFIGEQW 122
            H    +A    P +  PGNHD + A+ + L      P                F     
Sbjct: 61  AHLRRLLAPLDLPLLVCPGNHDDRAALRAGLDGLCPWPEPPGAGIPDGATLDLTFDLGPL 120

Query: 123 QILLLDSQVFGVPHGELSEFQLEWLERKLADAP--ERHTLLLLHHHPLPAGCSWLDQHSL 180
           +++ LDS   G   G LS  Q  WL+  L++A   ++  +L LHH P P G   LD   L
Sbjct: 121 RLIGLDSLRSGHSGGALSASQEAWLDSALSEAAFLDKPVVLFLHHPPFPMGIDHLDAARL 180

Query: 181 RNAGELDTVLAKFP-HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFK 228
             +  L  +L + P  V  LLCGH H+ +   W+G  +   P+    F 
Sbjct: 181 DQSETLGLLLDRHPGRVVRLLCGHAHRHVTTVWHGVAVTVCPAPAFAFA 229


>UniRef50_C7D8R5 Phosphodiesterase n=1 Tax=Thalassiobium sp. R2A62
           RepID=C7D8R5_9RHOB
          Length = 292

 Score =  193 bits (491), Expect = 5e-48,   Method: Composition-based stats.
 Identities = 58/243 (23%), Positives = 95/243 (39%), Gaps = 9/243 (3%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           + L  TD H+     E ++ ++        L     H  +   ++  GDL      + Y 
Sbjct: 27  KYLIFTDVHIVGAG-ETIIDLDPAVRLTQGLAHAVHHHPDAKAVIIAGDLTHHGLPSEYT 85

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGI--SPAKRVFIGEQWQILLLDS---Q 130
             AE +     P   + GNHD++P+       A       +         IL LD+    
Sbjct: 86  RLAEVLDECPLPVHVMLGNHDYRPSFRKVFTQAPDVDGFVQFAIHDGDHVILCLDTKDQT 145

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
                 G L E +L+WL   L    ++   L+ HH     G + +D+  L N  E   ++
Sbjct: 146 APDHHSGLLCETRLDWLAAHLETHADKQVTLIAHHPAFDTGFTGMDRIKLHNGAEFRDLI 205

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKP--HCSNFTLDTIAPG-WRTLE 247
           A+ P VK L+ GH+H+ +    NG  +    STC Q        + +L    PG +  L 
Sbjct: 206 AQHPCVKQLIHGHVHRTIMGQTNGVAVAMLKSTCHQIPMCLGDDDTSLAVDEPGAYGVLL 265

Query: 248 LHA 250
           L+ 
Sbjct: 266 LNE 268


>UniRef50_Q5Z214 Putative phosphodiesterase n=1 Tax=Nocardia farcinica
           RepID=Q5Z214_NOCFA
          Length = 495

 Score =  193 bits (490), Expect = 7e-48,   Method: Composition-based stats.
 Identities = 66/260 (25%), Positives = 103/260 (39%), Gaps = 16/260 (6%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + + Q++DTH         LG    E  + V+  +    H  D I+ TGD+ +      Y
Sbjct: 2   ILVAQVSDTHFD-------LGARNNERVERVMAFLADLAHRPDAILVTGDVTESGKPEQY 54

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSAL--QDAGISPAKRVFIGEQWQILLLDSQVF 132
                 + +   P   +PGNHD + A  + L  +    SP   V       +++LD+ + 
Sbjct: 55  AEARVALQA-DIPVWAIPGNHDERAAFRTELLGEQPSDSPINHVHRVGALTVIMLDTTIP 113

Query: 133 GVPHGELSEFQLEWLERKLADAPE-RHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
           G P G + E    WL   LADAP     +L +HH P       +D  +L     L  V+A
Sbjct: 114 GEPGGRIEEDTYRWLREVLADAPATGPIVLAMHHPPARLHSPIVDDIALAEPDRLADVVA 173

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTC----VQFKPHCSNFTLDTIA-PGWRTL 246
             P ++ +L GH H      + GR LL  PST       ++    +  +D    P     
Sbjct: 174 ADPRIRAVLTGHAHSAAATTFAGRPLLIAPSTASVLGGAWEVELPHRVMDYAPDPAVALH 233

Query: 247 ELHADGTLTTEVHRLADTRF 266
                G +TT    +    F
Sbjct: 234 VFDESGAMTTHFRTVPMGGF 253


>UniRef50_B5K790 Metallophosphoesterase n=1 Tax=Octadecabacter antarcticus 238
           RepID=B5K790_9RHOB
          Length = 265

 Score =  192 bits (488), Expect = 1e-47,   Method: Composition-based stats.
 Identities = 57/244 (23%), Positives = 94/244 (38%), Gaps = 16/244 (6%)

Query: 24  HLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIAS 83
           HL     + ++G++     Q  L+       +   ++  GDL     +  Y    + +  
Sbjct: 2   HLRGAG-KTIIGLDPTVRLQQSLDTALRDHPDAKALILMGDLTHSGRAEEYDILRDMLQD 60

Query: 84  FRAPCVWLPGNHDFQPAMYSALQDAGISP---AKRVFIGEQWQILLLDSQVFG---VPHG 137
              P  ++ GNHD +    +    A ++P    +R+      +I+ LD+          G
Sbjct: 61  CPIPVTYMLGNHDQRAPFRATFPTAPVTPQGHVQRIVDLPHHRIITLDTHDAAANPAHSG 120

Query: 138 ELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVK 197
            L   +L WL+  LA A  R  L+  HH P   G   +D  +LRN  +L   L   P   
Sbjct: 121 LLCADRLAWLDAALAGAGGRMALVFAHHPPHAVGLPGMDAIALRNGDDLLDRLRATP--A 178

Query: 198 YLLCGHIHQELDLDWNGRRLLATPSTCVQ-----FKPHCSNFTLDTIAPGWRTLELHADG 252
           +L CGH+H+ +     G       STC Q      +P  +    +  A G   L L   G
Sbjct: 179 HLFCGHVHRTISGQTRGVAFTMFKSTCHQAPLDLIRPDSTLSIAEPAAYG--LLLLSEGG 236

Query: 253 TLTT 256
            +  
Sbjct: 237 VIAH 240


>UniRef50_C9RR52 Metallophosphoesterase n=1 Tax=Fibrobacter succinogenes subsp.
           succinogenes S85 RepID=C9RR52_FIBSS
          Length = 249

 Score =  191 bits (487), Expect = 1e-47,   Method: Composition-based stats.
 Identities = 69/252 (27%), Positives = 118/252 (46%), Gaps = 14/252 (5%)

Query: 12  EARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
           +  ++I QI+D H+       +  ++  +++            + DL+V +GDLA + S+
Sbjct: 3   KKVLKIGQISDAHI-GDDDRLVQDIDVRKNFLTA--YNSESMKDLDLLVLSGDLADNAST 59

Query: 72  AAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQ---DAGISPAKRVFIGEQWQILLLD 128
            AY   A  I   + P   +PGNHD    M                  +  +   I  LD
Sbjct: 60  DAYSFIAGVIKDSKVPVCIIPGNHDNLEVMEKVFDLKDKVHNGKCYYRYDLDGRSIFFLD 119

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLD-QHSLRNAGELD 187
           S       G +S  QL WLE++ A   +   LL LHH P   G  ++D ++S++N  E+ 
Sbjct: 120 S-----ADGTVSSDQLSWLEQETAKI-DGEVLLFLHHPPCLCGHKFMDLRYSMKNIAEVQ 173

Query: 188 TVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLE 247
             L+K  ++K++  GH H E+ +    + +  TPST +Q  P+ + F L + AP WR +E
Sbjct: 174 ATLSKIKNLKHIFVGHYHSEMTIQLEDKTVYVTPSTQMQIDPNITVFCLSSAAPRWRLIE 233

Query: 248 LHADGTLTTEVH 259
              +  + T+V+
Sbjct: 234 -WGENFMETKVY 244


>UniRef50_Q20ZN1 Metallophosphoesterase n=1 Tax=Rhodopseudomonas palustris BisB18
           RepID=Q20ZN1_RHOPB
          Length = 252

 Score =  191 bits (487), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 65/253 (25%), Positives = 104/253 (41%), Gaps = 15/253 (5%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++I+ I D HL  +  E + G +T ++++     I P     DL+V  GD+A + S   Y
Sbjct: 1   MKIIVINDLHLVPEG-ELVRGQDTNKAFECGWREIAPLVECADLVVVNGDVAHNASVEGY 59

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQ--ILLLDSQVF 132
           + F       ++  +   GNHD +  +   L  A +     V         ++LLD+ V 
Sbjct: 60  RRFRRATQEIKSKLMVTVGNHDDRERLAIELGAAHLDNTGYVQAAHHAAASVVLLDTLVP 119

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNA-GELDTVLA 191
           G P G L   +L WL  +L  A ER  + ++HH PL  G   LD+ +L +    L  +L+
Sbjct: 120 GRPEGALCAVRLAWLREQLDLAAERPVIAIMHHPPLNLGVDALDEVALLDGCDALLELLS 179

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWR------- 244
           +      LL GH H               P+    F    + F L   AP +        
Sbjct: 180 RRSAPVTLLAGHHHISASGRIGPISYCICPA----FSGPPARFGLWGHAPNFGPGANGAC 235

Query: 245 TLELHADGTLTTE 257
            L +  DG +   
Sbjct: 236 ALTVRQDGRVDVR 248


>UniRef50_C6D6T3 Metallophosphoesterase n=1 Tax=Paenibacillus sp. JDR-2
           RepID=C6D6T3_PAESJ
          Length = 273

 Score =  191 bits (485), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 58/254 (22%), Positives = 99/254 (38%), Gaps = 9/254 (3%)

Query: 13  ARVRILQITDTHLFAQK-HEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
            +++ + +TDTH+ A          N  +  + V E I+        +V TGDL  + + 
Sbjct: 2   EKLKFVHLTDTHMNAPGVDNPFAKFNLADKVKRVFEHIKTASVSPAFVVITGDLTHEGNV 61

Query: 72  AAYQHFAEGIAS----FRAPCVWLPGNHDFQPAMYSAL--QDAGISPAKRVFIGEQWQIL 125
             Y++    +         P   + GNHD +         ++            +  +++
Sbjct: 62  QDYEYIRTIVDEGSALLGVPVHVVLGNHDHRAPFREGFLKEEPSEQAYYYSHTIQGVRLI 121

Query: 126 LLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGE 185
            L+SQV G  HGE+   QL WLE  L+   E  T++ LHH  L       D H L N  +
Sbjct: 122 GLNSQVKGQHHGEIDAEQLAWLEDTLSTPAENGTIVALHHPMLNINGMPAD-HVLANRDQ 180

Query: 186 LDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRT 245
           L  VL +   V  ++ GH+H      + G   +A   T    +    N        G+  
Sbjct: 181 LGNVL-EGTDVIGVVAGHVHTNNVGTYKGICHVAATGTAFGGEAAEDNHFKMVDFCGYNI 239

Query: 246 LELHADGTLTTEVH 259
           + ++ +G     V 
Sbjct: 240 VSVYEEGVTVQTVV 253


>UniRef50_C6WAT1 Metallophosphoesterase n=1 Tax=Actinosynnema mirum DSM 43827
           RepID=C6WAT1_ACTMD
          Length = 245

 Score =  190 bits (484), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 70/244 (28%), Positives = 96/244 (39%), Gaps = 10/244 (4%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           +   +DTH     H A          + V+  +R      D  V TGD+  +     Y+ 
Sbjct: 4   LAHFSDTHFDGGDHAA-------PRAERVVGYLRGLARPVDAAVLTGDVVDNGLRVEYEE 56

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSAL--QDAGISPAKRVFIGEQWQILLLDSQVFGV 134
            A  +     P + LPGNHD +      L  +  G  P  RV    +  + L DS V G 
Sbjct: 57  AARVLGGLGRPLLALPGNHDSRSPFREVLLGEGPGDGPVNRVARVGEVVLALCDSTVPGQ 116

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
             G L++  LEWL+  LA+A    TL+ LHH P+P     LD   L     L  V+    
Sbjct: 117 DGGALADETLEWLDAVLAEAAGAPTLVCLHHPPVPVRHPVLDPIGLDAPERLARVVRGRK 176

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPH-CSNFTLDTIAPGWRTLELHADGT 253
            +  LLCGH H  +     G  +L+ P       P        D  AP      +  DG 
Sbjct: 177 GLLALLCGHSHSPMVGSLAGVPVLSAPGVVSTLAPPWEGEKPNDRGAPPALAFHVVEDGQ 236

Query: 254 LTTE 257
           LTT 
Sbjct: 237 LTTH 240


>UniRef50_A9DF72 Possible 3',5'-cyclic-nucleotide phosphodiesterase, cpdA n=1
           Tax=Hoeflea phototrophica DFL-43 RepID=A9DF72_9RHIZ
          Length = 278

 Score =  190 bits (484), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 60/268 (22%), Positives = 103/268 (38%), Gaps = 19/268 (7%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++++ I+D HL       +LG++   +++  L  +  H  + + IV TGDL       +Y
Sbjct: 1   MKLVHISDIHL---NEAPILGLDPVANFKRCLAYVEAHDADAERIVITGDLTHHGGEESY 57

Query: 75  QHFAEGIASFR-----APCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQ---ILL 126
           +   + +A+       AP   L GNHD +    S        P   V   E+      + 
Sbjct: 58  RLLVDILAASPLQDKLAP-RLLIGNHDHRETFASVFSSTHRDPNGFVQWTEETPAGVFVY 116

Query: 127 LDSQVFGVPHGELSEFQLEWLERKL--ADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAG 184
           +D+   G   G   E ++ WL   L  A +      L +HH+P+    +  D   + N  
Sbjct: 117 MDTVDQGRHGGRYCEARMAWLAGVLDDARSSGARAFLFMHHNPVRVNVANADIIGIINER 176

Query: 185 ELDTVLAKFPHV-KYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPH----CSNFTLDTI 239
           EL  +L ++  V  ++  GH H  L     G    A  ST     P      +      +
Sbjct: 177 ELQALLKRYNDVIAHMFFGHCHYSLSGSVAGISYSAPRSTNHPCWPDFSGMANRMGFGEL 236

Query: 240 APGWRTLELHADGTLTTEVHRLADTRFQ 267
           AP +    L  D  +   +  L   + Q
Sbjct: 237 APNYNVCFLRDDSIVVHTIDFLDAEKVQ 264


>UniRef50_B7BFD3 Putative uncharacterized protein n=1 Tax=Parabacteroides johnsonii
           DSM 18315 RepID=B7BFD3_9PORP
          Length = 238

 Score =  190 bits (484), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 53/244 (21%), Positives = 103/244 (42%), Gaps = 8/244 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +RI+ I+D HL       +   +T   +   ++ I+   +  D I+ +GDL+ D S+ +Y
Sbjct: 1   MRIIHISDIHLENHG-LPIWNTDTKLHFDKAIKKIQTMDN-IDAIIISGDLSNDGSAWSY 58

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
            +    +A    P    PGNHD     Y +   +       +F+   W  ++L+S + G 
Sbjct: 59  NYIDNLLAKTNIPTFCCPGNHDNLDIFYGS-HKSWFYKNCELFMLNGWTFIMLNSVMAGK 117

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
             G       ++L+  L       T+++LHH P+     WL++  L N    + ++ K+ 
Sbjct: 118 SRGNFYPD--KFLD--LLKHSCGPTVIVLHHPPIEQD-GWLNRKLLENRDVFNDIIHKYK 172

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTL 254
           +++ +L GH H       +G    +  S    F P    F +     G+  + L+    +
Sbjct: 173 NIRLVLYGHTHHHEIKTIDGIIYSSASSIGFAFHPKLLKFQIAHGREGFSLITLNDSNII 232

Query: 255 TTEV 258
              +
Sbjct: 233 IENI 236


>UniRef50_C9CTH4 Phosphodiesterase n=6 Tax=Proteobacteria RepID=C9CTH4_9RHOB
          Length = 284

 Score =  190 bits (484), Expect = 4e-47,   Method: Composition-based stats.
 Identities = 57/266 (21%), Positives = 96/266 (36%), Gaps = 11/266 (4%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++ + +TDTH+       L G N        +++I     + D  V TGDL     + AY
Sbjct: 1   MKFIHLTDTHVIG-GDRTLYGANPARRLALAVDSINAEHGDADFTVVTGDLTHWGDADAY 59

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV---FIGEQWQILLLDSQV 131
             F   I     P V + GNHD   A      +        V       Q   L LD++ 
Sbjct: 60  AAFEAQIRRLSMPLVLMVGNHDDTAAFARCFPEVARDEHGFVQSRRETSQGSCLFLDTKA 119

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
            G   G     +L WL ++L ++      L +HH P   G S +D   + +      V+ 
Sbjct: 120 PGTHAGGYCAQRLGWLRQQLDESSG-PVFLFMHHPPFRHGISSMDAIMMLDHHAFWRVIE 178

Query: 192 KFP-HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFK----PHCSNFTLDTIAPGWRTL 246
                +++L  GH+H+ +  +W G           Q              D   P +  +
Sbjct: 179 PHRARIRHLFFGHVHRAIFGNWRGISYSCMRGLNHQVTLDLGTDADTIDGDFAEPAYGVV 238

Query: 247 ELHADGTLTTEVHRLADTRFQPDTAS 272
            L  +  +T  +H  A+   +    +
Sbjct: 239 -LADEDCVTVHLHEFANRTPRFSLHA 263


>UniRef50_Q3IG69 Cyclic 3',5'-adenosine monophosphate phosphodiesterase n=1
           Tax=Pseudoalteromonas haloplanktis TAC125
           RepID=Q3IG69_PSEHT
          Length = 281

 Score =  190 bits (483), Expect = 5e-47,   Method: Composition-based stats.
 Identities = 80/277 (28%), Positives = 126/277 (45%), Gaps = 30/277 (10%)

Query: 11  GEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQS 70
            +  +RI  +TD HLFA ++    GVNT   +Q  LE +   Q +   +V  GDL QD S
Sbjct: 11  NKPSLRIAHVTDCHLFADRNAEYFGVNTATYFQQALEHMALQQLD--AVVFGGDLTQDHS 68

Query: 71  SAAYQHFAEGIAS--FRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE-------- 120
             +Y  F+E I++     P  WLPGNHD   A+   +    I  AKR+            
Sbjct: 69  VESYLLFSELISNSTLTCPVFWLPGNHDE-IALLEQISGGQIKAAKRLVANNLTNNLTNN 127

Query: 121 -----------QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLP 169
                        ++LL++S+    P G ++   L  +   LA    +  L+  HH+PLP
Sbjct: 128 LTNNLTNNASTDIELLLINSKGL-TPAGWVTSEHLNEISDCLAQPVSKQ-LVFCHHNPLP 185

Query: 170 AGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKP 229
               +LD+H L N  +L   L    +V  L+ GH+H +    +    + ATP++ VQF  
Sbjct: 186 IN-GYLDKHMLENGPQLLNTLVNNGNVAALIHGHVHNDYTQCFRELDIYATPASSVQFTK 244

Query: 230 HCSNFTLDTIAPGWRTLELHAD-GT--LTTEVHRLAD 263
           H   +      P +R L +++  G   + T+V  L+ 
Sbjct: 245 HSKAWQQQNNGPAYRMLYINSSQGQVHINTDVIWLSA 281


>UniRef50_Q2J3S6 Metallophosphoesterase n=5 Tax=Rhodopseudomonas palustris
           RepID=Q2J3S6_RHOP2
          Length = 274

 Score =  189 bits (481), Expect = 8e-47,   Method: Composition-based stats.
 Identities = 61/252 (24%), Positives = 102/252 (40%), Gaps = 10/252 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++ + +TDTH  A+    + G++  E  +A +  I     E   ++ TGDLA     AAY
Sbjct: 1   MKFVVLTDTHFVARG-RRIYGLDPAERLRAAIGCINRDHPEIAFVIVTGDLAHWGEDAAY 59

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAG---ISPAKRVFIGEQWQILLLDSQV 131
           +  AE +   RA  + L GNHD +                  + + + +   ++ LD+  
Sbjct: 60  EALAEVLGELRALTILLMGNHDKRDGFARYFPGVPRDADGFVQTMQVFDAATVVTLDTLN 119

Query: 132 FGVP--HGELSEFQLEWLERKLADAP-ERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
              P   G L + +L +LE  L  AP +R  LL  HH P   G  ++D   L N      
Sbjct: 120 EAAPNHEGLLCDARLAFLEHALTSAPTDRPLLLFQHHPPFDTGLRYMDTIRLANPEAEWE 179

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHC---SNFTLDTIAPGWRT 245
           V+A+     YL  GH+H+ +   W G       +   Q         +      AP +  
Sbjct: 180 VIARTRRPDYLFMGHLHRPIAGVWRGIPFHIQRALAHQVAFDLVTEGHIPGSHEAPDYAH 239

Query: 246 LELHADGTLTTE 257
           + +  D  +  +
Sbjct: 240 VSVEGDRIVIHQ 251


>UniRef50_A3W656 Ser/Thr protein phosphatase family protein n=3 Tax=Rhodobacteraceae
           RepID=A3W656_9RHOB
          Length = 265

 Score =  188 bits (479), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 51/220 (23%), Positives = 89/220 (40%), Gaps = 7/220 (3%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQH---EFDLIVATGDLAQDQSSA 72
           R L ++D H+  +       ++T    +  ++ +          D ++ TGD++ D S+ 
Sbjct: 3   RFLHLSDLHVVPEGQLVSGQLDTARLLRLAIDTLTTRLDAIGPVDAVLVTGDISDDGSTE 62

Query: 73  AYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQD----AGISPAKRVFIGEQWQILLLD 128
           +Y+     +       + +PGNHD +    +A  D            +      +++ LD
Sbjct: 63  SYEIARRDLMRLGHRLLVVPGNHDGRETFRAAFSDLPEMRPTGLIDWIADIGDTRVIGLD 122

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           + + G   G L +  L  L   L+ A  R TL+ LHH PL  G  ++D   L N   L  
Sbjct: 123 TLIEGKGGGVLRDESLALLSEALSTAGGRQTLVALHHPPLRTGLRFMDAIGLENPNALRI 182

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFK 228
           VL +      +L GH+H           ++  PS C  F 
Sbjct: 183 VLDQHDAPVRVLAGHVHGVYHGLLGRHPVVTAPSCCSAFA 222


>UniRef50_Q28NL1 Metallophosphoesterase n=2 Tax=Rhodobacteraceae RepID=Q28NL1_JANSC
          Length = 277

 Score =  188 bits (477), Expect = 2e-46,   Method: Composition-based stats.
 Identities = 64/243 (26%), Positives = 96/243 (39%), Gaps = 17/243 (6%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           + L  TD H+     E ++G++    +Q  L        +   IV  GDL      A Y 
Sbjct: 7   KALIFTDLHITPPG-ETIIGLDPLARFQEGLAHALSRHPDAQHIVLLGDLTHTGDPAEYA 65

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDA--GISPAKRVFIGEQWQILLLDSQVFG 133
                +A    P     GNHD +  + +A   A      A+        ++L+LD+  + 
Sbjct: 66  RLVPALADCPIPLTVTMGNHDLRDHLRNAFPTALNPDGFAQTARDLGPLRLLILDTHDYD 125

Query: 134 -----VPHGELSEFQLEWLERKLADAPE--RHTLLLLHHHPLPAGCSWLDQHSLRNAGEL 186
                   G L E +L WL+ +LA A +  +  ++  HH P P G   +D   L NA  L
Sbjct: 126 NQAPLEQDGWLCETRLAWLDAELARAADDGKDVVVFAHHPPCPVGFWAMDAIGLANADAL 185

Query: 187 DTVLAKFPHVKYLLCGHIHQELDLDW-----NGRRLLATPSTCVQFKP--HCSNFTLDTI 239
            + L   PHVK+L+CGHIH+ +          G  +    S C Q         F     
Sbjct: 186 LSRLHAAPHVKHLICGHIHRTIHASASSPAGGGLPVTILKSPCHQVPMILGQGTFADSVD 245

Query: 240 APG 242
            PG
Sbjct: 246 EPG 248


>UniRef50_Q15YS5 Metallophosphoesterase n=1 Tax=Pseudoalteromonas atlantica T6c
           RepID=Q15YS5_PSEA6
          Length = 250

 Score =  188 bits (477), Expect = 2e-46,   Method: Composition-based stats.
 Identities = 74/253 (29%), Positives = 132/253 (52%), Gaps = 13/253 (5%)

Query: 16  RILQITDTHLFAQ-KHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS--- 71
           ++ QI+D HLFA  +H     +N + + QAVL+ +     +  +++ +GD++ +  +   
Sbjct: 4   KVAQISDCHLFADKRHAGYQNINPYTTLQAVLKNVGLCHPD--MVIVSGDVSAENDAVKG 61

Query: 72  -AAYQHFAEGIAS--FRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLD 128
            A+YQ F++        AP + +PGNHD   A+ + L      P      G  W++  L+
Sbjct: 62  LASYQLFSQLWQQSKISAPLLVIPGNHDHLEALNNELNHLAGWPLSTS-AGPYWKVHGLN 120

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           ++      GE+S  QL++L  ++   P++H LL++HHHP   G  W+D H  RN  E   
Sbjct: 121 TKTDDSS-GEISMRQLQYLNEQVNLHPQQHHLLVVHHHPYACG-GWMDNHPWRNRDEFIQ 178

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLEL 248
            + + P +K ++ GHIHQ  +        ++ PSTC Q+  +   F+    APG+R +EL
Sbjct: 179 NVEQQPQIKAVIYGHIHQASETRSQDCVFMSAPSTCWQWA-NSKEFSASGEAPGYRVIEL 237

Query: 249 HADGTLTTEVHRL 261
             +G + + + R+
Sbjct: 238 ADNGQVDSHIIRI 250


>UniRef50_A3K5W8 Phosphodiesterase n=1 Tax=Sagittula stellata E-37
           RepID=A3K5W8_9RHOB
          Length = 249

 Score =  186 bits (473), Expect = 6e-46,   Method: Composition-based stats.
 Identities = 51/236 (21%), Positives = 92/236 (38%), Gaps = 11/236 (4%)

Query: 32  ALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWL 91
            + G++ ++     L  I  H  +   +V +GDL +     AY    + +     P   +
Sbjct: 2   TIGGLDPYDRLARALGHIAEHHRDAGFVVISGDLTEYAEREAYARLRQALTMLPMPVRLM 61

Query: 92  PGNHDFQPAMYSALQDAGISPAKRVF---IGEQWQILLLDSQVFGVPHGELSEFQLEWLE 148
            GNHD +   +   +D        V       + + +  D+   G   G     +L WL 
Sbjct: 62  MGNHDDRDVFFDVFRDHPRDADGYVNHATDLREGRFIFCDTVETGRDEGHFGPGRLRWLT 121

Query: 149 RKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGE--LDTVLAKFPH-VKYLLCGHIH 205
            +LA        L  HH+PL  G    D +SLR+  +  L  +L      V Y+  GH+H
Sbjct: 122 EQLAGCER--AFLFFHHNPLHIGDPSADGYSLRDEDQGPLRDLLKANAQKVAYMFFGHVH 179

Query: 206 QELDLDWNGRRLLATPSTCVQFKPH---CSNFTLDTIAPGWRTLELHADGTLTTEV 258
             L    +G      PST +Q  P+     +  +  + P +R + +  +  +  ++
Sbjct: 180 APLCGTMSGIAFSGVPSTMMQRIPNLTPAEHTAIGPLEPAYRVVLVRGEDVVIHQI 235


>UniRef50_A1AWV4 Metallophosphoesterase n=5 Tax=Bacteria RepID=A1AWV4_RUTMC
          Length = 234

 Score =  186 bits (472), Expect = 8e-46,   Method: Composition-based stats.
 Identities = 59/245 (24%), Positives = 110/245 (44%), Gaps = 16/245 (6%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
            +QI+D H+     E  +GVNT           +    + D ++ +GDL  + +  +Y+ 
Sbjct: 6   FVQISDCHI--DNVEYAMGVNTH--VNLKKIINKIINIDTDALLISGDLTHNGTITSYKT 61

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPH 136
             + +   +   + + GNHD    + +       S     F   +W+I+  +S       
Sbjct: 62  LQQILFPVQIKLLVISGNHDIDNNLNTIFSKNLFSQ----FTLRKWEIISTNSVQTSKTS 117

Query: 137 GELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHV 196
           G L++ +L+ L   L  +  ++ L++LHH  +P   +W D  SL N   L  VL K+P +
Sbjct: 118 GFLTKNELKKLNFNLTQSIAKYILIVLHHPIVPMNSTWDDSLSLENPKALFNVLDKYPKI 177

Query: 197 KYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTT 256
           + +L GH HQ  +    G ++++ PST +QF         +    G+    L+ +G LT 
Sbjct: 178 QAILFGHAHQAAEFSRLGVKIISCPSTALQFN--------NETRIGFNHYTLYDNGQLTI 229

Query: 257 EVHRL 261
           +   +
Sbjct: 230 DTQWI 234


>UniRef50_D2QL03 Metallophosphoesterase n=1 Tax=Spirosoma linguale DSM 74
           RepID=D2QL03_9SPHI
          Length = 247

 Score =  185 bits (470), Expect = 1e-45,   Method: Composition-based stats.
 Identities = 64/255 (25%), Positives = 103/255 (40%), Gaps = 14/255 (5%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGD-LAQDQSSAA 73
           +RI  +TD HL A+      GV+  +++   L  +   +     +V  GD       S+ 
Sbjct: 1   MRIAFLTDMHLGAEGELP-EGVDVRQNFLKALAFLTELKPSC--LVLGGDFCISVGDSSI 57

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSAL---QDAGISPAKRVFIGEQWQILLLDSQ 130
           YQ   + +     P   +PGNHD    +        D            E    L LDS 
Sbjct: 58  YQWVKKQVDELPFPYYVIPGNHDDPTMLAEVFNKMHDLHGGELYYALSLEGRPTLFLDSS 117

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQ-HSLRNAGELDTV 189
                 G  S+ Q  W    L+   + + ++ +HH PLPA   ++D+ +  R + E   +
Sbjct: 118 K-----GAFSDQQWTWFRDYLSALRDNNIVVFMHHPPLPADVQFMDRKYPFRQSEEFIEL 172

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELH 249
           +   P    ++CGH H E  +      +L +PST  Q K     F +DT+  G R + L 
Sbjct: 173 VRDLPCHVTVICGHYHVEKVVQRGNLLVLLSPSTFYQMKQDTVGFAVDTLRVGIREINLT 232

Query: 250 ADGTLTTEVHRLADT 264
             GT  + V+ L   
Sbjct: 233 THGT-NSAVYYLDPE 246


>UniRef50_A5V3T9 Metallophosphoesterase n=2 Tax=Sphingomonadaceae RepID=A5V3T9_SPHWW
          Length = 289

 Score =  184 bits (467), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 57/230 (24%), Positives = 90/230 (39%), Gaps = 8/230 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + I Q+TD H+             +    A ++ +       D +  TGDL      A+Y
Sbjct: 1   MLIAQLTDLHIGFDLENP--DELNFHRVAAAIDYVMGLSVVPDRLFLTGDLTDHGDVASY 58

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAG--ISPAKRVFIGEQWQILLLDSQVF 132
           +     I     P     GNHD + AM     D        + V    + +I++LD+   
Sbjct: 59  ERLKGLIDGCGFPVHLCVGNHDDRAAMKQVFPDLPVEDGFVQYVIDEPEVRIIVLDTLDP 118

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT-VLA 191
           G   G     +  WL+ +LA+ P +  L++LHH P+  G  W+  H       +    + 
Sbjct: 119 GHHGGAFGHRRAGWLKARLAEVPGKPVLIVLHHPPIETGIPWMTAHQTEPWVVMLDKAIG 178

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAP 241
             P V  +  GHIH+ +   W GR L   PST  Q     +   +D   P
Sbjct: 179 DRPGVTMI-SGHIHRSITTSWRGRMLAVAPSTAPQVALEMA--PIDPERP 225


>UniRef50_D2PMS5 Metallophosphoesterase n=1 Tax=Kribbella flavida DSM 17836
           RepID=D2PMS5_9ACTO
          Length = 249

 Score =  183 bits (466), Expect = 4e-45,   Method: Composition-based stats.
 Identities = 70/251 (27%), Positives = 106/251 (42%), Gaps = 20/251 (7%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           I  ++D HL              +  + V   +R      D+++ TGDLA   +   Y  
Sbjct: 4   IAHLSDPHLDGTPEAQ-------DRLRRVTAYVRSFTRPVDVVLVTGDLADHGT--EYAE 54

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISP-----AKRVFIGEQWQILLLDSQV 131
            A  +A+F  P + LPGNHD      + L     SP       +V      + +LLD+ V
Sbjct: 55  VAAELAAFDVPVLVLPGNHDLSEPFRAGLTAYVDSPGAGHPVHQVRDVGGARFVLLDTTV 114

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
            G  HGEL+   L WL+  L++  +    +  HH P+      +DQ  LR+A     VL 
Sbjct: 115 PGEDHGELAAESLGWLDGVLSEPTDGPVFVAFHHPPVGLHAPAIDQWLLRDAAPFAAVLR 174

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATP----STCVQFKPHCSNFTLDTIAPGWRTLE 247
           + P V  L  GH+H  +   +    LL  P    +  + F+P  +   LD  AP    L 
Sbjct: 175 RHP-VTALFAGHLHNGVATTFADLPLLLAPGIRSAVPLPFEPAAAQGLLDPTAPPGLALH 233

Query: 248 LH-ADGTLTTE 257
           LH  D  + T+
Sbjct: 234 LHTPDAAVVTK 244


>UniRef50_A3JT02 Putative uncharacterized protein n=1 Tax=Rhodobacterales bacterium
           HTCC2150 RepID=A3JT02_9RHOB
          Length = 271

 Score =  182 bits (462), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 49/254 (19%), Positives = 95/254 (37%), Gaps = 16/254 (6%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           +IL ++D HL     + ++G+N  E  ++ L+       + D ++  GDL        ++
Sbjct: 3   KILLLSDLHLRGPNQK-IIGINPMERLKSALDHALACHPDADRLILLGDLTHSGKVLEFE 61

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSAL---QDAGISPAKRVFIGEQWQILLLDSQVF 132
                      P  +  GNHD +    +     +       + V     +++++LD+   
Sbjct: 62  RLKSLTDQCPIPVTFTLGNHDNRDHFRNVFANVEPDENGHIQSVIDIGDYRMVVLDTLDG 121

Query: 133 G-----VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELD 187
                    G+    +  WL++++A A  R  L+ +HH P+  G   +D   L +     
Sbjct: 122 PPFRNYHHSGKYCAARQSWLDQQIATAEGRKILIFMHHPPMDVGFPGMDAIKLADGNAF- 180

Query: 188 TVLAKFPH-VKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAP---GW 243
             L ++ H   +L CGHIH+ +    NG       S   Q     S        P    +
Sbjct: 181 --LKRYAHKATHLFCGHIHRTISGTTNGLGFTIFKSPVHQMPMELSGTESSYSVPEPGAY 238

Query: 244 RTLELHADGTLTTE 257
             + L  +  +   
Sbjct: 239 GVILLTENSIIAHT 252


>UniRef50_D2AYX4 Metallophosphoesterase n=10 Tax=Actinomycetales RepID=D2AYX4_STRRD
          Length = 247

 Score =  181 bits (460), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 68/246 (27%), Positives = 100/246 (40%), Gaps = 13/246 (5%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           + QI+D HL   +               V++ +R   H  D ++ TGD+A   + A Y+ 
Sbjct: 5   LAQISDLHLDGSERAT-------RRATRVMDYLRALPHAVDALLVTGDIADHGTEAEYEE 57

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAG--ISPAKRVFIGEQWQILLLDSQVFGV 134
            A  +++   P +  PGNHD +PA   AL        P  RV       IL+ DS + G 
Sbjct: 58  AARILSA-PFPVLTCPGNHDARPAYRKALLGEPAADGPINRVHHVTGTAILMCDSTIPGR 116

Query: 135 PHGELSEFQLEWLERKLADAPER-HTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKF 193
             G L    L+W++  LA  PE    L+  H  P+       D   LR   +L  +L   
Sbjct: 117 DEGRLDAETLDWIDTTLAGLPEGTPALIAFHQPPVELHHPLPDSGMLRRPEDLAALLDAH 176

Query: 194 PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFK-PHCSNFTLD-TIAPGWRTLELHAD 251
           P V  ++ GH H      + GR L+  P+     + P   +   D    PG     L  D
Sbjct: 177 PRVAAVVTGHAHTAAASTFAGRPLIVGPAITWTLRLPWEGDRPADRDQPPGLAFHVLTED 236

Query: 252 GTLTTE 257
             LTT 
Sbjct: 237 LRLTTH 242


>UniRef50_Q9V2G8 Predicted phosphohydrolase, putative n=3 Tax=Pyrococcus
           RepID=Q9V2G8_PYRAB
          Length = 505

 Score =  180 bits (458), Expect = 4e-44,   Method: Composition-based stats.
 Identities = 55/254 (21%), Positives = 107/254 (42%), Gaps = 21/254 (8%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
           ++ I  I+DTH+  +          ++SY   L A   +   FDL++ TGD+  +     
Sbjct: 3   KMLIAHISDTHITNEV--------AFKSYAYDLIANEINTRPFDLVIHTGDVTNNGLREE 54

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFG 133
           Y+H +  +     P +  PGNHD +   Y    +  I P   V+  +   I+ LDS +  
Sbjct: 55  YEHASYLLKKIEKPLIVAPGNHDARNVGYELF-EKYIGPLIGVYEFKDGVIIWLDSTIPD 113

Query: 134 VPHGELSEFQLEWLERKLADAPERH-TLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
           +  G +  ++ +WL+ KL +   +   ++  HHH +P   +  +++ L NAG++  +L  
Sbjct: 114 LSDGRVGGYKFKWLKAKLEEYSHKKIKIVAAHHHLVPLPDTGRERNVLFNAGDVLDLLLS 173

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATP-STCVQFKPHCSNFTLDTIAPGWRTLELHAD 251
              V   +CGH H           +     ++C + +    N         +  +++  D
Sbjct: 174 HD-VTLYMCGHKHVPNVYRVEDLVVDNAGCASCRKTRKGDVN--------SYNIVKITKD 224

Query: 252 GTLTTEVHRLADTR 265
             +   + RL    
Sbjct: 225 -KVKVVIRRLTGDE 237



 Score = 74.1 bits (181), Expect = 4e-12,   Method: Composition-based stats.
 Identities = 35/249 (14%), Positives = 92/249 (36%), Gaps = 18/249 (7%)

Query: 11  GEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQS 70
           G   +RI+ ++      + + +        + +  + AI   +++ D++V  GD+ +   
Sbjct: 254 GRRLLRIVHVS------ESNVSDRVYFRKRTLENAIRAIN-EKYKPDIVVHCGDVVEKGI 306

Query: 71  SAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQ 130
              ++   E     +A  + +PG++D     Y   ++    P   +     +  + + S 
Sbjct: 307 ERYFEMALEYYEKVKAEKIIVPGHNDISYLGYELFKEYFGEP--EIVERGDFVFIPILSA 364

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
            +    G +     + L R L D  E+  ++++HH+ +P      +   L +AG +  ++
Sbjct: 365 QYETQIGVVGRTGQKMLSRLLDDFEEKFRIIVMHHNLVPVP-GVREIGYLEDAGNVLKII 423

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHA 250
                 +  L GH      +      ++   S              +     +  ++++ 
Sbjct: 424 TD-KKTELTLTGHGGNSNAVKVEKSPIINAGSISW-------ELHRNPFGNSFNVIDIYE 475

Query: 251 DGTLTTEVH 259
           D  +  E+ 
Sbjct: 476 DMIVAFEIQ 484


>UniRef50_C0WNK1 3',5'-cyclic-nucleotide phosphodiesterase n=3 Tax=Lactobacillus
           RepID=C0WNK1_LACBU
          Length = 291

 Score =  179 bits (455), Expect = 8e-44,   Method: Composition-based stats.
 Identities = 59/272 (21%), Positives = 102/272 (37%), Gaps = 21/272 (7%)

Query: 14  RVRILQITDTHLFAQKHEA--LLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
           + +I+QI+DTHL     +      ++  E  + V + I     + DLIV +GDL  +  +
Sbjct: 5   QCKIVQISDTHLTPAGAKPANHQHLDPEEKLRTVFDDIYNTNVDPDLIVISGDLIHEGDA 64

Query: 72  AAYQHFAEGIA----SFRAPCVWLPGNHDFQPAMYSALQDAG--ISPAKRVFIGEQWQIL 125
             Y  F   +        AP   + GNHD     Y          +        E  +  
Sbjct: 65  EVYADFHHMLDQEQERLMAPIKVILGNHDRTDQFYKGFLGKKRVATRCYYHESLEGLECY 124

Query: 126 LLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGE 185
            LD++   +  G L + QL WL+ +L +  +R  ++ +HH         +    L+N  +
Sbjct: 125 FLDTKCGDIEQGYLDQTQLHWLKNQLQEY-QRPGIIFMHHPLYGPPLQQMRYSILQNGDD 183

Query: 186 LDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRT 245
           L  V+    HVK +  GH+H       +G   +   ST         +    T    +  
Sbjct: 184 LLNVID-HTHVKAIFSGHVHFANSYVVDGILNVVADSTAYHINCANPHEHFVTDGTAYNV 242

Query: 246 LELHAD-----------GTLTTEVHRLADTRF 266
           + +  D           GT T    ++ +T F
Sbjct: 243 ITVDGDDIGVEQRLLYLGTKTINAFKIPNTDF 274


>UniRef50_Q8TVF8 Predicted calcineurin superfamily phosphohydrolase n=1
           Tax=Methanopyrus kandleri RepID=Q8TVF8_METKA
          Length = 270

 Score =  178 bits (452), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 49/206 (23%), Positives = 88/206 (42%), Gaps = 9/206 (4%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           +I+ I+D H+            + E +   +E I   + +   ++ TGDL  +     Y+
Sbjct: 4   KIVHISDLHISP-----YRKSWSPEVFYRGIEQINDLRPDV--VIVTGDLTDNGLVREYE 56

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVP 135
             +  +    AP V +PGNHD +   +   +D      +   +     ++ LDS    V 
Sbjct: 57  EVSSLLEKIEAPVVPVPGNHDARNLGWMTFEDVFGDRYRVERVSADLYVVGLDSSEPDVD 116

Query: 136 HGELSEFQLEWLERKLADAPERH-TLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
           +G+L   + EWLE  L   P      + +HHH LP   +  +++ L +AGE+  +  K+ 
Sbjct: 117 YGQLGRERQEWLEETLRRIPGGACKCIAMHHHLLPVPGAGRERNVLVDAGEMINLCIKY- 175

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLAT 220
            V  +LCGH H           ++  
Sbjct: 176 GVDLVLCGHRHVPFAAKVEDTVVVNA 201


>UniRef50_A9CI50 Putative uncharacterized protein n=1 Tax=Agrobacterium tumefaciens
           str. C58 RepID=A9CI50_AGRT5
          Length = 291

 Score =  174 bits (442), Expect = 3e-42,   Method: Composition-based stats.
 Identities = 57/225 (25%), Positives = 93/225 (41%), Gaps = 10/225 (4%)

Query: 14  RVRILQITDTHLF-AQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA 72
           RV  + +TD H+   Q  +  L   T  +  A L  ++      + IV +GDL     + 
Sbjct: 4   RVNFVHLTDLHIGNPQVQDDDLYSETSATLSATLAQVKALVPPPEFIVVSGDLTNRGDAG 63

Query: 73  AYQHFAEGIAS--FRAPCVWLPGNHDFQPAMYSALQDAG---ISPAKRVFIGEQWQILLL 127
           +Y+     +A     AP ++  GNHD +   Y  + D       P     +     I+++
Sbjct: 64  SYEELKRLMAEAELDAPVLFALGNHDRRDGFYPVMLDRHEGVDEPYDHAEVIAGIHIIVM 123

Query: 128 DSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHP---LPAGCSWLDQHSLRNAG 184
           D+ V G   G     Q+EWLE +L + PE   LL++HH P        +  +  S  +  
Sbjct: 124 DTSVPGKVGGAFEPGQIEWLEEELENHPELPKLLVMHHAPALDFDRPEAEWESLSFDDTE 183

Query: 185 ELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKP 229
            LD +L +   V  +L GHIH +    W G  ++          P
Sbjct: 184 ALDELLFEHD-VIGILAGHIHCDRMSHWQGIPVVVGIGQHFATDP 227


>UniRef50_Q0RKV8 Putative uncharacterized protein n=1 Tax=Frankia alni ACN14a
           RepID=Q0RKV8_FRAAA
          Length = 301

 Score =  174 bits (441), Expect = 3e-42,   Method: Composition-based stats.
 Identities = 66/243 (27%), Positives = 101/243 (41%), Gaps = 20/243 (8%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
            G A + ++Q++DTHL          V+T+   + V   +         I+ TGDLA D 
Sbjct: 4   TGPAELTLIQVSDTHLLPAGQLMHDRVDTFALLETVAATVASSTGPVAGILLTGDLADDG 63

Query: 70  SSAAYQHFAEGIASF----RAPCVWLPGNHDFQPAMYSALQD---------------AGI 110
           S A+Y+   + I        AP V+  GNHD + A  + L                 +  
Sbjct: 64  SPASYRRLRQIIDPLAATFDAPVVYAMGNHDERLAFRAELLGGAGVPVGLDGQAGEWSTD 123

Query: 111 SPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPA 170
            P   V + +  +++ LDS   G   G L++ QL WL   LA    R TLL++HH PLP+
Sbjct: 124 HPCDSVHLVDGLRLVALDSTTPGRHDGWLTDAQLAWLADVLATPAPRGTLLIVHHPPLPS 183

Query: 171 GCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPH 230
               +    L  A  L  V+A    V+ +L GH H        G  +  +P+      P 
Sbjct: 184 PVPTVHLLRLAAAERLADVVA-GTDVQMILSGHAHHAGAGALAGIPVWVSPALAYDTDPL 242

Query: 231 CSN 233
             +
Sbjct: 243 PPD 245


>UniRef50_A3U194 Putative uncharacterized protein n=1 Tax=Oceanicola batsensis
           HTCC2597 RepID=A3U194_9RHOB
          Length = 287

 Score =  173 bits (438), Expect = 7e-42,   Method: Composition-based stats.
 Identities = 69/257 (26%), Positives = 109/257 (42%), Gaps = 17/257 (6%)

Query: 15  VRILQITDTHLFAQK-HEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
           +  + +TD H+ A    + +L  +T E+ +  LE I         IVA+GDL       A
Sbjct: 6   LTFIHMTDLHVNASGVEDDMLFNDTRETLERTLEEIGRMDDAPAFIVASGDLTNRGDPEA 65

Query: 74  YQHFAEGIAS--FRAPCVWLPGNHDFQPAMYSALQDAGIS---PAKRVFIGEQWQILLLD 128
           Y+  AE  A+     P ++  GNHD +    +A  +       P     + +   ++ LD
Sbjct: 66  YRTVAEIFAASGLDIPVLFALGNHDKREGFAAAFPELYTDASQPFDHDRVIDGLHLITLD 125

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHP-LPAGCSWLDQHSLR--NAGE 185
           S V     G     Q++WL+ +LA  P+   LL++HH P +    S ++  SL      E
Sbjct: 126 SSVPNEIGGYWEAGQIDWLKDRLAAHPDLPKLLVMHHAPMIDLTASDMEWESLSAVATEE 185

Query: 186 LDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLAT----PSTCVQFKPHCSNFTLDTIAP 241
           L T +A    V  +L GH+H +    W+G  ++        T V   P   N      A 
Sbjct: 186 LRTAIAGHD-VVGILSGHVHMDRVAQWHGVPVIIGTGHHAGTDVVALPGAFNML---DAT 241

Query: 242 GWRTLELHADGTLTTEV 258
           G+   +L   G  TT V
Sbjct: 242 GFAVCQLFPAGLTTTFV 258


>UniRef50_D0L6V7 Metallophosphoesterase n=1 Tax=Gordonia bronchialis DSM 43247
           RepID=D0L6V7_GORB4
          Length = 245

 Score =  173 bits (438), Expect = 7e-42,   Method: Composition-based stats.
 Identities = 52/244 (21%), Positives = 89/244 (36%), Gaps = 11/244 (4%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           +  I+D H    +             ++ L  I       D ++ TGDLA + S++ Y+ 
Sbjct: 4   VAHISDLHFNGTRFN-------RSRIESTLSYINARADGIDALLITGDLADEGSASEYRE 56

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGIS-PAKRVFIGEQWQILLLDSQVFGVP 135
               + S   P +   GNHD +    +AL D   S P            L+ DS + G  
Sbjct: 57  AYGVLES-PLPMLITAGNHDVRENFSAALLDHETSEPLNWSQRIGDVLFLVADSSIAGRN 115

Query: 136 HGELSEFQLEWLERKLADAPER-HTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
            G LS+  L W+  ++    +    L+  HH P+     ++D         L  ++ + P
Sbjct: 116 DGYLSDDTLTWMADEITMHGDETPVLIAFHHPPVKLSMPFMDSIRQTGEDRLAALVGRHP 175

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFK-PHCSNFTLDTIAPGWRTLELHADGT 253
           ++   LCGH H      +  R L   P        P   +  ++   P      +  +G 
Sbjct: 176 NIVAFLCGHAHTPAVTRFADRPLCIAPGVASTLNLPFEGHDIVNRGQPPGIAFHILDEGR 235

Query: 254 LTTE 257
             T 
Sbjct: 236 FVTH 239


>UniRef50_C8XD18 Metallophosphoesterase n=1 Tax=Nakamurella multipartita DSM 44233
           RepID=C8XD18_NAKMY
          Length = 292

 Score =  171 bits (435), Expect = 2e-41,   Method: Composition-based stats.
 Identities = 66/276 (23%), Positives = 109/276 (39%), Gaps = 13/276 (4%)

Query: 10  AGEARVR----ILQITDTHLFAQKHEALLGVNTWESYQ---AVLEAIRPHQHEFDLIVAT 62
            G A +R    +  ++D+HL +        ++   +     AVL +        D ++ +
Sbjct: 7   DGSAPLRPTHVLAHLSDSHLTSAGVRYNQVLDADAALDRAVAVLRSAVADGRPLDAVILS 66

Query: 63  GDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGI-SPAKRVFIGEQ 121
           GDL       AY+     +     P ++  GNHD +   + +L   G   P  +      
Sbjct: 67  GDLTDTGDPDAYRRLRAAVEPLGVPVLYATGNHDVRTEFHRSLLGRGDEGPVLQSVQVGG 126

Query: 122 WQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLR 181
            ++L LDS + G  HG L+   L  L   LAD     T+++LHH PLP     L   +L 
Sbjct: 127 LRMLALDSTIPGAGHGRLTAEHLAELTAALADPAPEGTIVVLHHAPLPPPSPLLSYFALE 186

Query: 182 NAG--ELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTI 239
            A    L   +A    V+ +L GH H           +    ST ++  P   N    T 
Sbjct: 187 AASRIALRDAIA-GTDVRLVLAGHHHLAQSGTLGAIPVAVAGSTAIRTDPLAPNGHERTW 245

Query: 240 APG-WRTLELHADGTLTTEVHRLADTRFQPDTASEG 274
           A G +  ++++ D T+T  V  +       D  + G
Sbjct: 246 ASGSFNLVQVYPD-TITVSVIPVDGAAPVFDLDAAG 280


>UniRef50_A9WNR5 Putative 3',5'-cyclic-nucleotide phosphodiesterase n=1
           Tax=Renibacterium salmoninarum ATCC 33209
           RepID=A9WNR5_RENSM
          Length = 309

 Score =  171 bits (434), Expect = 2e-41,   Method: Composition-based stats.
 Identities = 67/229 (29%), Positives = 108/229 (47%), Gaps = 21/229 (9%)

Query: 13  ARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA 72
             + IL ++DTH+ A+   + + V+T ++    L A+ P + E DL+V +GD++ D ++ 
Sbjct: 8   ETLSILHLSDTHVLAKGLHSNV-VDTRQNLLEALRALVPVE-ELDLVVVSGDVSDDGTAE 65

Query: 73  AYQHFAEGIASF----RAPCVWLPGNHDFQPAMYSAL----------QDAGISPAKRVFI 118
           +Y+   E + +F     A  ++  GNHD +P  +  L          QD G  P     +
Sbjct: 66  SYRMVQELVENFASHRGARAIYTMGNHDGRPGFWEVLGNGHPDSPAEQDGGQLPVYGSSV 125

Query: 119 GEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQH 178
              ++I+ LD+ V G  HG L   QL+WL  +L  A E  T+L+LHH P+       D  
Sbjct: 126 LGGFRIISLDTSVPGRTHGYLDRGQLDWLTEELGSASEAGTVLVLHHPPVEPVTPLHDGI 185

Query: 179 SLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDW----NGRRLLATPST 223
            L+N  +L  VL     V+ +L GH H  L            +L  P  
Sbjct: 186 ELQNPEDLLEVL-HGSDVRLILSGHYHHGLVDSVLLGDQLIPVLVAPGI 233


>UniRef50_A6W423 Metallophosphoesterase n=1 Tax=Kineococcus radiotolerans SRS30216
           RepID=A6W423_KINRD
          Length = 274

 Score =  169 bits (429), Expect = 9e-41,   Method: Composition-based stats.
 Identities = 65/214 (30%), Positives = 97/214 (45%), Gaps = 12/214 (5%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           R+LQ++DTHL A        V+T  +    LEA+R      D +V +GD++ D + A+Y+
Sbjct: 3   RVLQLSDTHLMAAGALHNGLVDTTAALVHALEALRDVGP-LDAVVVSGDVSDDGTVASYE 61

Query: 76  HFAEGI----ASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQV 131
              + +    A   A  V+  GNHD        L      P + V      +I++LDS V
Sbjct: 62  AARDLVGGFAAERGAVAVFAMGNHDVAGPFEQVL-----GPTRSVHDVAGVRIVVLDSSV 116

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
            G  +GEL   QL W    LAD   R +++++HH PLPA     +   L+   EL   LA
Sbjct: 117 PGRGYGELPAEQLSWAREVLADPAPRGSVVVVHHSPLPAPTVLHEGLRLQRPAELLDALA 176

Query: 192 KFPHVKYLLCGHIHQELDLDW-NGRRLLATPSTC 224
               V+ +L GH H        +G      P+  
Sbjct: 177 -GTDVRAVLSGHYHHPFAATLPSGLAAFVAPAVA 209


>UniRef50_A5FYX3 Metallophosphoesterase n=1 Tax=Acidiphilium cryptum JF-5
           RepID=A5FYX3_ACICJ
          Length = 274

 Score =  169 bits (429), Expect = 9e-41,   Method: Composition-based stats.
 Identities = 73/264 (27%), Positives = 109/264 (41%), Gaps = 9/264 (3%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
            G   + + Q +D HL A    A   V T         A        D +V TGDLA   
Sbjct: 5   PGAPPLLVAQFSDLHLRAPGLTANRIVETNMLAARAFAAFAALAPAPDALVITGDLADRG 64

Query: 70  SSAAYQHFAEGIAS-FRAPCVWLPGNHDFQPAMYSALQD----AGISPAKRVFIGEQWQI 124
            + AY+  A  I    R P + +PGNHD + AM + L D       +   R       ++
Sbjct: 65  EAEAYRLLAGLIERHVRVPVILIPGNHDDRAAMRATLGDRLAADDEAGVNRPAEHLPVRL 124

Query: 125 LLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAG 184
           L LDS + G  HG L + QL +L  +LA  P R   +LLHH P+  G + +D   L NA 
Sbjct: 125 LPLDSTIGGESHGRLGDGQLRFLRDRLAADP-RPAAILLHHPPIATGIAHMDAIGLENAA 183

Query: 185 ELDTVLAKF-PHVKYLLCGHIHQELDLDWNGRRLLATPSTCV--QFKPHCSNFTLDTIAP 241
            L+  +A     V  L CGH+H+ +     G  ++  PS     QF       +   + P
Sbjct: 184 ALEAAIAPHAARVAGLWCGHVHRMIHGRLAGAPVVIAPSVAHQVQFDLTPDGPSALVLEP 243

Query: 242 GWRTLELHADGTLTTEVHRLADTR 265
               +      + T+++  +    
Sbjct: 244 PAFVMHRWDGASFTSQMVFVDSYP 267


>UniRef50_C9AD97 Phosphoesterase n=3 Tax=Enterococcus casseliflavus
           RepID=C9AD97_ENTCA
          Length = 270

 Score =  169 bits (429), Expect = 9e-41,   Method: Composition-based stats.
 Identities = 57/258 (22%), Positives = 93/258 (36%), Gaps = 21/258 (8%)

Query: 15  VRILQITDTHLFA---QKHEALLGV-----NTWESYQAVLEAIRPHQHEFDLIVATGDLA 66
           + +L I+D H         E   G+     N     +  ++  +      DL+V +GDL 
Sbjct: 1   MNVLHISDIHFRESYLPCEEGYQGMLAAMQNPLIPLEECIQDAKARA-AIDLVVISGDLT 59

Query: 67  QDQSSAAYQHFAEGIASF--RAPCVWLPGNHDFQPAMYSALQD-----AGISPAKRVFIG 119
           +D + A Y    + +       P V   GNHD +       Q      A  +P  +V+  
Sbjct: 60  EDGAPADYASLKQYLEKAFGSVPIVVTLGNHDIKRHFRQGWQGKSVETASDTPFNQVYET 119

Query: 120 EQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHS 179
           E   I+  D+  +G   G + E Q EWL+  LA   E+  + + HHH LP   S     +
Sbjct: 120 ETLAIVTFDNSCYGYADGIVDERQFEWLQATLAQLKEKKIVFVTHHHLLPDQAS---TPA 176

Query: 180 LRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTI 239
              A  L  +L ++  +  +L GH H        G       S     +           
Sbjct: 177 WAGANRLVALLQQY-QISCILSGHTHHAFTGTIAGIPYYTVASMSFVGEDEGDGMVRFEE 235

Query: 240 APGWRTLELHADGTLTTE 257
             G+       +G L  +
Sbjct: 236 RYGYNLYRF-EEGALVHQ 252


>UniRef50_C6VLV6 3',5'-cyclic-nucleotide phosphodiesterase n=3 Tax=Lactobacillus
           plantarum RepID=C6VLV6_LACPJ
          Length = 290

 Score =  168 bits (426), Expect = 2e-40,   Method: Composition-based stats.
 Identities = 62/264 (23%), Positives = 99/264 (37%), Gaps = 10/264 (3%)

Query: 14  RVRILQITDTHLFAQKHEALLG--VNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
            ++++QI+D HL       + G   + W     +++ IR      DLIV TGDL  D S+
Sbjct: 9   PLQVIQISDLHLTPHGQVPVHGQQYDPWGKLANIIDDIRRLPTMPDLIVFTGDLIHDGSA 68

Query: 72  AAYQHFAEGI----ASFRAPCVWLPGNHDFQPAMYSALQDAGISPAK-RVFIGEQWQILL 126
             YQ     +    A F      + GNHD + A Y     A   P               
Sbjct: 69  DDYQRLHAIVHTMEAEFDCHVRVILGNHDRRAAFYEGYLPADPGPYYASRMRIGNNDFYF 128

Query: 127 LDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGEL 186
           LDS+V G   G L+  QL+WL + L  AP +   L LHH       + +    L+N   L
Sbjct: 129 LDSKVSGYEAGWLAPQQLQWLGKHLRQAPTKRAFLFLHHPLDGPTMTNMHYAILQNTPAL 188

Query: 187 DTVLAKFPHVKYLLCGHIHQELDLDW-NGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRT 245
            +VL    ++  +  GH+H        +    +   S       H  +         ++ 
Sbjct: 189 LSVLRGH-NLGGVFSGHVHFVSSYLIGDNILNVVAGSAAYAIDCHDLHHHYVHEGSSYQI 247

Query: 246 LELHADGTLTTEVHRLADTRFQPD 269
           + +   G +     +L   +   D
Sbjct: 248 ITIDR-GQVGVTTRQLLHGKAVID 270


>UniRef50_C7MAF7 Predicted phosphohydrolase n=1 Tax=Brachybacterium faecium DSM 4810
           RepID=C7MAF7_BRAFD
          Length = 284

 Score =  167 bits (423), Expect = 4e-40,   Method: Composition-based stats.
 Identities = 59/223 (26%), Positives = 99/223 (44%), Gaps = 10/223 (4%)

Query: 15  VRILQITDTHLFAQKHEA-LLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
           +R+L +TDTHL+          ++T  + + +L+ +     + D +V TGD ++D ++ +
Sbjct: 1   MRLLHLTDTHLYGDPAARHYDRIDTAAALRGLLDRLGTL-RDIDAVVHTGDASEDGTAQS 59

Query: 74  YQHFAEGIAS----FRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE---QWQILL 126
           Y+   E +        AP   + GNHD        +      PA +  +       ++++
Sbjct: 60  YRLLHEILDPFAASLDAPLAVVMGNHDVSAVYGETVVPGERLPAAQDRVVPLPRDGRLIV 119

Query: 127 LDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGEL 186
           LDS V G  +G L+  QL+WL  +LA      ++L +HH PL A  + L    L     L
Sbjct: 120 LDSSVPGAGYGHLAPEQLDWLREQLAVPAAGGSVLAIHHPPLVAATALLRGLDLDGLDAL 179

Query: 187 DTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKP 229
             VLA    V  +L GH H E+  +  G  +   P       P
Sbjct: 180 AAVLA-GSDVSIVLSGHYHHEMSGEIAGIPVHVAPGITNVVDP 221


>UniRef50_A1SEE2 Metallophosphoesterase n=2 Tax=Actinobacteria (class)
           RepID=A1SEE2_NOCSJ
          Length = 313

 Score =  166 bits (422), Expect = 6e-40,   Method: Composition-based stats.
 Identities = 73/276 (26%), Positives = 104/276 (37%), Gaps = 22/276 (7%)

Query: 13  ARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA 72
            R  +  ++D HL A        ++T    +  L  +   +     +V TGDLA     A
Sbjct: 9   PRHVVAHLSDPHLLAGGARQYGVIDTEAGLRLALTRLSRLETPPHALVFTGDLADKAEPA 68

Query: 73  AYQHFAEGI----ASFRAPCVWLPGNHDFQPAMYSAL----QDAGISPAKRVFIGEQWQI 124
           AY    E +    A   A  VW+ GNHD +      L         +P  RV      +I
Sbjct: 69  AYSRLRELVEPAAAEMGAAVVWVMGNHDERAPYARGLFGVEGADADAPQDRVHEVAGLRI 128

Query: 125 LLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHS-LRNA 183
           + LD+ V G  HGEL++ QL WL   LA      TLL LHH P+P       +   L + 
Sbjct: 129 VALDTSVPGYHHGELADDQLAWLAEVLATPAPHGTLLALHHPPIPIPMMPAAEIIELLDQ 188

Query: 184 GELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAP-- 241
             L  VL     V+ +L GH H      + G  +    +TC    P      +  +    
Sbjct: 189 HRLADVL-GGTDVRCILGGHFHYSTYSTFAGIPVSVASATCYTSDPAPLERFVSGVNGHQ 247

Query: 242 GWRTLELHADGTLTTEVHRLADTRFQPDTA--SEGY 275
               + L+ D        R+  T    D A    GY
Sbjct: 248 AMTMVHLYDD--------RVVHTVVPVDEAPEVSGY 275


>UniRef50_D2EUB1 Metallophosphoesterase n=1 Tax=Bacteroides sp. D20
           RepID=D2EUB1_9BACE
          Length = 245

 Score =  166 bits (420), Expect = 9e-40,   Method: Composition-based stats.
 Identities = 58/246 (23%), Positives = 107/246 (43%), Gaps = 12/246 (4%)

Query: 20  ITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAE 79
           ++D HL       + G +T E +   ++ I+  Q + D I+ +GD++ D S ++Y     
Sbjct: 1   MSDLHLTQDG-STIWGEDTREKFIIAIDMIKKMQ-DIDAILVSGDISNDGSFSSYIFADR 58

Query: 80  GIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFG------ 133
             +S   P  W  GNHD    + +    +         I   WQI++L+S V        
Sbjct: 59  LFSSTNIPTYWSLGNHDNLDLLKNNNLLSYCKLVCEATIY-GWQIIILNSIVHDEEQPGK 117

Query: 134 -VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
               G +    +  ++ K+    ++ T+++LHH  L  G  W D   L+N  +   ++  
Sbjct: 118 NRSRGVIDIDTMIKIKNKIYTL-KKPTIVVLHHPALEIG-GWQDLKILKNRDKFREIIES 175

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADG 252
             +V+ +L GHIH+  D   NG R    P     F    SN+ +   A G+  + ++ + 
Sbjct: 176 SEYVRIVLAGHIHEFTDRTLNGIRYSTAPGLGFAFSSKLSNYEIQHGAEGFNLITINKNK 235

Query: 253 TLTTEV 258
            L  ++
Sbjct: 236 ILINKI 241


>UniRef50_Q6ACA7 Putative uncharacterized protein n=1 Tax=Leifsonia xyli subsp. xyli
           RepID=Q6ACA7_LEIXX
          Length = 280

 Score =  165 bits (417), Expect = 2e-39,   Method: Composition-based stats.
 Identities = 61/202 (30%), Positives = 89/202 (44%), Gaps = 11/202 (5%)

Query: 13  ARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA 72
           AR+RIL ++DTHL          V+T  +   VL          D++ A+GDL+ D S A
Sbjct: 3   ARLRILHLSDTHLCGDGRLHYGMVDTLAALDRVLAHASSLD-AVDMVAASGDLSDDGSPA 61

Query: 73  AYQHFAEGI----ASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLD 128
           +Y+   E +    A   A   +  GNHD   A  S L      P +R      ++IL +D
Sbjct: 62  SYRLLQERLEPWAAERGAVVAYAMGNHDLPDAFESVL-----GPRERALDANGFRILTVD 116

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           + V    +G +   QL+ L   LA+  E  T ++LHH P P      D   L +   L  
Sbjct: 117 TTVPCAGYGRVDTAQLDRLSEALAEPSEHGTAIVLHHPPAPPTTRLFDTLRLVDPEPLLE 176

Query: 189 VLAKFPHVKYLLCGHIHQELDL 210
           V +    V+ +L GH H  L  
Sbjct: 177 VCSA-GDVRLILAGHYHHALVT 197


>UniRef50_O66909 Putative uncharacterized protein n=1 Tax=Aquifex aeolicus
           RepID=O66909_AQUAE
          Length = 249

 Score =  164 bits (415), Expect = 4e-39,   Method: Composition-based stats.
 Identities = 56/265 (21%), Positives = 103/265 (38%), Gaps = 25/265 (9%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++I  I+D H+  + +E  LG N  +   A          + DL++ TGDL      A Y
Sbjct: 1   MKIAHISDLHVKCEWYEDRLGNNLVKYLNA---------QKPDLLIITGDLTDYGYYAEY 51

Query: 75  QHFAEGIASFRA-PCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFG 133
           +     +        V +PGNHD +   Y   ++   +     +  E   I+ +DS +  
Sbjct: 52  KRAYSFLELIEVEKRVVVPGNHDARNEGYELFEEFFGTRMPY-YEDEYMVIIGMDSSLPD 110

Query: 134 VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKF 193
              G +     ++L   L D  ++  ++ LHHH +P   +  D   L +AG L  V+ + 
Sbjct: 111 REEGHIGRKGYKFLRETLKDKGDKLKIVALHHHVVPIPATGSDLAILTDAGNLMKVVDEL 170

Query: 194 PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGT 253
             V+ +L GH H+      N      T  T    +    ++      P +  L L  +  
Sbjct: 171 -GVELVLTGHKHKAWVWKLNE-TYYVTAGTATTRRLKAKDY------PSFYMLYLEDEKN 222

Query: 254 L-----TTEVHRLADTRFQPDTASE 273
           +      TE  ++ +  +  +    
Sbjct: 223 IRMEKVNTETLKVEEV-YTLNFEEG 246


>UniRef50_A5UK60 Predicted phosphohydrolase, calcineurin-like superfamily n=2
           Tax=Methanobrevibacter smithii RepID=A5UK60_METS3
          Length = 247

 Score =  164 bits (415), Expect = 4e-39,   Method: Composition-based stats.
 Identities = 52/252 (20%), Positives = 102/252 (40%), Gaps = 20/252 (7%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           I+ I+D H+     E        + +   +  I     +  +I+ TGDL  +   + +  
Sbjct: 4   IVHISDLHISELGFEE-------DVFIKAVAEINAINPD--MIILTGDLTNNGYYSEFIQ 54

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPH 136
             + +  F AP   +PGNHD +   Y   ++     + ++   +++ ++ LDS    +  
Sbjct: 55  ATKYLEMFDAPLFAVPGNHDARNLGYETFEELIGECSWKLTKDDEFVVIGLDSSSPDISS 114

Query: 137 GELSEFQLEWLERKLADA--PERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
           G +   Q  W+E +L      E  +++ LHHH +P   +  +++ L +AG++   L    
Sbjct: 115 GNVGRPQHLWMEHQLDQCVIEELFSIVALHHHVIPIPKTGRERNVLTDAGDVLKTLTDHE 174

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTL 254
            V  +L GH H       N    +   S         SN         +   E+  D T+
Sbjct: 175 -VDLVLAGHKHVPNIWKMNNTLFVNAGS-------LSSNKLRGDDKNSYNVYEITED-TI 225

Query: 255 TTEVHRLADTRF 266
              ++++   RF
Sbjct: 226 RIFLNKVDGERF 237


>UniRef50_A9DXP9 Putative uncharacterized protein n=1 Tax=Oceanibulbus indolifex
           HEL-45 RepID=A9DXP9_9RHOB
          Length = 268

 Score =  163 bits (413), Expect = 6e-39,   Method: Composition-based stats.
 Identities = 56/210 (26%), Positives = 90/210 (42%), Gaps = 8/210 (3%)

Query: 16  RILQITDTHLF-AQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           R + +TD H+     ++  L  +T  + + V+E I     + D +VA+GDL       +Y
Sbjct: 3   RFVHLTDLHISHPDLNDPHLQSDTPATLRRVVEVINGMAPQPDFVVASGDLTNQGDQQSY 62

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIG--EQWQILLLDSQVF 132
           +   + + +  AP V   GNHD +    +     G++ A            ++ LDS V 
Sbjct: 63  ELLRDILGTMHAPLVLALGNHDKRAGFNAVFA-PGLADAPYFHDAPQGDLHVITLDSSVP 121

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNA--GELDTVL 190
           G   G L + Q E+L   L   PE   LL++HH P       L   SL  A    L  +L
Sbjct: 122 GKVAGALDDAQFEFLGAALQRHPELAKLLVIHHPP-RVDPEALAWGSLDEASSARLAEML 180

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLAT 220
                V  +L GH+H      W+G  ++ +
Sbjct: 181 K-GQRVAGVLSGHVHVNRVSHWHGIPVVIS 209


>UniRef50_C5CDX7 Metallophosphoesterase n=1 Tax=Kosmotoga olearia TBF 19.5.1
           RepID=C5CDX7_KOSOT
          Length = 358

 Score =  162 bits (411), Expect = 1e-38,   Method: Composition-based stats.
 Identities = 53/238 (22%), Positives = 98/238 (41%), Gaps = 18/238 (7%)

Query: 37  NTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHD 96
           N+  ++  ++E I  +  E   +V TGD+  D S   Y  F + ++  + P + +PGNHD
Sbjct: 63  NSISTFGKIIEQINTN-PEITFVVNTGDMVFDGSVTKYNFFLKQLSKLQKPFIPVPGNHD 121

Query: 97  FQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPE 156
                 +   +    P    F  +Q   ++LDS         +  +Q++WLE +L ++ +
Sbjct: 122 IADGGMNNYVE-FFGPLYYAFAVDQVYFIVLDSSNEET----IGAWQMKWLEEQLKNSQK 176

Query: 157 RHTLLLLHHHPLPAGCSWLDQ---HSL---RNAGELDTVLAKFPHVKYLLCGHIHQELDL 210
                +  H P+      +D+   HSL   +NA EL  +L K+ +V  +  GHIH     
Sbjct: 177 HKYRFVFLHVPIFDPRLPMDKQPGHSLKNTKNAMELLKLLQKY-NVTMVFAGHIHGYFRG 235

Query: 211 DWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTEVHRLADTRFQP 268
           +W G   + T                +     +  + +   G +  EV ++    F  
Sbjct: 236 EWEGVPYIVTGGAG----AELVGLNKEHYFYHYLIVRVKDTG-IDYEVVKVNSPDFNV 288


>UniRef50_Q7NJG1 Glr1871 protein n=1 Tax=Gloeobacter violaceus RepID=Q7NJG1_GLOVI
          Length = 318

 Score =  161 bits (407), Expect = 3e-38,   Method: Composition-based stats.
 Identities = 51/229 (22%), Positives = 88/229 (38%), Gaps = 16/229 (6%)

Query: 8   PLAGEARVRILQITDTHLFAQKHEAL--LGVNTWESYQAVLEAIRPHQHEFDLIVATGDL 65
           P+  E ++  +QI+D HL      +   L        Q  +E +       D +V TGDL
Sbjct: 18  PVKLEPQLNFVQISDVHLRPNAGRSGWWLSERPEHLLQLAVEKVCALG-GVDFVVFTGDL 76

Query: 66  AQDQSSAAYQHFAEGIASFRAPCVWLPGNHDF----------QPAMYSALQDAGISPAKR 115
                +AA   F     +   P   + GNHD           +      L          
Sbjct: 77  FDQAEAAALDQFVAIAGALPCPYHVVVGNHDVVGKPWPGRLTKQTFAERLA-LPEKLYYS 135

Query: 116 VFIGEQWQILLLDSQVFGVPH--GELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCS 173
           V +   +++++LD+     PH  G L   Q+EWL  +L    +   ++ LHH P+     
Sbjct: 136 VPVKPGYRLIVLDTVPAPFPHAQGCLPAEQMEWLRWQLLVHRDEQVIVALHHPPVAPAYF 195

Query: 174 WLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPS 222
              + +  +  +   ++A  P+V  +L GH+H      +  R   + PS
Sbjct: 196 RDFRLNPLDGSQFAELMAASPNVVAVLSGHLHVPRRWSYRKRPYFSAPS 244


>UniRef50_D2PQZ3 Metallophosphoesterase n=1 Tax=Kribbella flavida DSM 17836
           RepID=D2PQZ3_9ACTO
          Length = 293

 Score =  161 bits (407), Expect = 3e-38,   Method: Composition-based stats.
 Identities = 67/235 (28%), Positives = 104/235 (44%), Gaps = 23/235 (9%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
           R RIL ++DT +     +   GV+   + + +L   R H  + DL+V +GD+A D S   
Sbjct: 4   RHRILHLSDTQVGRDGRDE-DGVDAVAALERMLHDAR-HLPDLDLVVVSGDIADDGSVEG 61

Query: 74  YQHFAEGIASF----RAPCVWLPGNHDFQPAMYSALQDAGISPAKR-------------- 115
                + +A+F      P V+  GNHD +    +AL    + P                 
Sbjct: 62  CVAVRDRVAAFAAARGIPHVYCTGNHDDRSTFATALGSGHLGPDGTDLGRLMESGGPERV 121

Query: 116 -VFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCS- 173
            V      +I+ LDS V G  HG LS+ QL+WL   L       T++++HH P+    S 
Sbjct: 122 AVSEVNGVRIVTLDSLVPGAAHGALSDRQLQWLANLLETPASSGTVIVVHHPPVYLESSV 181

Query: 174 WLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFK 228
            +    LR++  L +VLA    V+ +LCGH H +L     G  +  TP    +  
Sbjct: 182 LMGTVGLRDSDRLASVLAGRD-VRAVLCGHFHLQLAATLAGVPVWVTPGVVTRID 235


>UniRef50_Q1AXD2 Metallophosphoesterase n=1 Tax=Rubrobacter xylanophilus DSM 9941
           RepID=Q1AXD2_RUBXD
          Length = 271

 Score =  160 bits (406), Expect = 4e-38,   Method: Composition-based stats.
 Identities = 49/241 (20%), Positives = 102/241 (42%), Gaps = 21/241 (8%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +RI+Q++D H+ +       G+   E  +A +      + +  L+   GDL  +     +
Sbjct: 1   MRIVQMSDIHVGS-------GLFRPELLEAAVRETNELRPD--LVAVAGDLTMEGYRWEF 51

Query: 75  QHFAEGIASFRAP-CVWLPGNHDFQPAMYSALQDAGISPAKRVFIG---EQWQILLLDSQ 130
           +     +     P  V + GNHD +   Y   +D   S A+ + +     + +++ +DS 
Sbjct: 52  EEARRHLDRLECPHVVVVMGNHDAKSVGYRHFEDIFGSRARSLVVPSPQGEAKVVAIDST 111

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
              +  GE+      W++ +         +L++HHH L    +  D + LR+AG++  +L
Sbjct: 112 KPDLDEGEVGREYYAWIDSEFRGWERGPKILMIHHHILAVPGTGRDVNILRDAGDVMAML 171

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHA 250
            +   V  +L GH H       +G R++ + +         S     T+ P +  ++L  
Sbjct: 172 RELK-VDMVLSGHRHVPYVWSISGVRVIHSGTV-------SSLRVRGTMPPSYNLIDLDD 223

Query: 251 D 251
           +
Sbjct: 224 E 224


>UniRef50_C7D3F7 Predicted protein n=5 Tax=Enterococcus RepID=C7D3F7_ENTFA
          Length = 272

 Score =  160 bits (405), Expect = 5e-38,   Method: Composition-based stats.
 Identities = 50/254 (19%), Positives = 90/254 (35%), Gaps = 18/254 (7%)

Query: 15  VRILQITDTHLFAQKHEALLGV--------NTWESYQAVLEAIRPHQHEFDLIVATGDLA 66
           + IL ++D H      +   G         N     ++ L ++   + + DL++ +GDL 
Sbjct: 1   MDILHLSDIHFRRNYEKTKDGYKGMLTKMENPLIRLESSLTSLLKIK-KIDLVIISGDLT 59

Query: 67  QDQSSAAYQHFAEGIASF--RAPCVWLPGNHDFQPAMYSALQD--AGISPAKRVFIGEQW 122
           +D     Y    + + +     P +   GNHD +        +      P   V    ++
Sbjct: 60  EDGEPEDYAFLKQKLQTILQGIPMIVTLGNHDIKKNFRIGWLNQIGTERPYNVVQTYPEF 119

Query: 123 QILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRN 182
            I+ LD+     P G +++ Q +WL+  L    ++  LL++HHH L    S     +L  
Sbjct: 120 HIISLDNSEHDNPDGHMNKEQKDWLQTTLKKLSDKPILLVMHHHLLREQSSMP---TLPE 176

Query: 183 AGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPG 242
           A E   +L     +  +L GH H       NG             +             G
Sbjct: 177 AEETIQLLKS-SDILGVLTGHTHHPYLHHINGIPYYTVAGMSFVGEDEGQGIVRFEENYG 235

Query: 243 WRTLELHADGTLTT 256
           +    +   G  T 
Sbjct: 236 YNLYSIDK-GRFTH 248


>UniRef50_A6CD50 Cyclic 3',5'-adenosine monophosphate phosphodiesterase n=1
           Tax=Planctomyces maris DSM 8797 RepID=A6CD50_9PLAN
          Length = 301

 Score =  160 bits (405), Expect = 5e-38,   Method: Composition-based stats.
 Identities = 62/249 (24%), Positives = 95/249 (38%), Gaps = 21/249 (8%)

Query: 20  ITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLA-QDQSSAAYQHFA 78
           + DTH+  +KH     + T    + ++  +     +   ++  GDLA +D     Y+HFA
Sbjct: 44  LNDTHI-GEKHPPKSPIPTH--LREIVTELVELPQKPACVLINGDLALRDGQPGDYRHFA 100

Query: 79  EGIASFR---APCVWLPGNHDFQPAMYSALQDAGISPAK------RVFIGEQWQILLLDS 129
             I   +          GNHD +   Y  +Q+   S          V   +     LLDS
Sbjct: 101 SLIQPLQEAKIDTHLTLGNHDERDVFYEVMQEQRPSAPPVKSRHISVVQTKFANFFLLDS 160

Query: 130 -QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
                V  G L + Q  WL   L    ++  +++ HH+P   G        L ++ EL  
Sbjct: 161 LHKTMVTQGTLGKEQRSWLANALDAHADKPAIIVTHHNPRLGGDPVHFPGGLTDSEELWE 220

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLEL 248
           +L   P VK  + GHIH   +    G  +L TP+T     P       D    GW   +L
Sbjct: 221 LLVSRPQVKAYIHGHIHDRGNAQHKGIHILNTPATSYVANP-------DHSTTGWTIAQL 273

Query: 249 HADGTLTTE 257
              G   T 
Sbjct: 274 TPTGVTLTT 282


>UniRef50_C6VU97 Metallophosphoesterase n=1 Tax=Dyadobacter fermentans DSM 18053
           RepID=C6VU97_DYAFD
          Length = 244

 Score =  160 bits (404), Expect = 6e-38,   Method: Composition-based stats.
 Identities = 63/247 (25%), Positives = 105/247 (42%), Gaps = 19/247 (7%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           RI QITD HL  ++  A  G +T  + + +L+ +         I+ TGD+    + A+YQ
Sbjct: 3   RIAQITDIHLM-EEWSAQNGADTDTNLKLILQDVGARGIRD--IIFTGDI---GNPASYQ 56

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIG---EQWQILLLDSQVF 132
            F   +  F      +PGNHD    +    Q A +     +F       ++ + LDS   
Sbjct: 57  RFFALMKDFD--FTIIPGNHDKFADIRPHYQPAYLEGKSEMFHAVEETHFKYIFLDSSSD 114

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
                 +SE QL WLE +L     RH LL +HH  L    +   ++ L N   +  +L +
Sbjct: 115 S-----VSEMQLRWLENELVTT--RHVLLFIHHPVLQVLTAVDFKYPLLNRAAVKELLVR 167

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADG 252
                 +  GH H +            TP+  VQ + +     + +   G+R +EL  + 
Sbjct: 168 SDREITIFSGHYHTDDFTKEENLTQYVTPAASVQMEKNPLEIVVHSRYYGYRIIEL-EER 226

Query: 253 TLTTEVH 259
           +++T V 
Sbjct: 227 SVSTHVV 233


>UniRef50_C8QH10 Metallophosphoesterase n=3 Tax=Enterobacteriaceae
           RepID=C8QH10_9ENTR
          Length = 240

 Score =  157 bits (398), Expect = 3e-37,   Method: Composition-based stats.
 Identities = 59/229 (25%), Positives = 93/229 (40%), Gaps = 15/229 (6%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + + QI+D H              ++   A L+ +       D++V TGDL  +Q  A Y
Sbjct: 1   MLVAQISDIHASPDNDNLQR----FDKALAWLDQLN-----PDVLVLTGDLIDNQWLAGY 51

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSAL-QDAGISPAKRVFIGEQWQILLLDSQVFG 133
              AE ++  + P   LPGN D +  M +     A        +     ++L LDS + G
Sbjct: 52  ALIAERLSQKKWPSRVLPGNSDDRRQMRAVWGATAADEFLHFNYDAGDLRLLGLDSTLVG 111

Query: 134 VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKF 193
           V  G +    + WLE++L D      LL LHHH   +G   LD+       EL  ++   
Sbjct: 112 VTAGSV-VNHIAWLEQQLRDIHTSPALLFLHHHVFASGIPSLDKTMCAGVPELAALIRHM 170

Query: 194 PH-VKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAP 241
           P  +  +  GH+H+ +     G       S C     +   F  DT+ P
Sbjct: 171 PGKLLAIASGHVHRPIAGALAGVPAYICGSLCPA---NPVWFGTDTVPP 216


>UniRef50_C8S8V3 Metallophosphoesterase n=1 Tax=Ferroglobus placidus DSM 10642
           RepID=C8S8V3_FERPL
          Length = 373

 Score =  157 bits (398), Expect = 3e-37,   Method: Composition-based stats.
 Identities = 46/238 (19%), Positives = 94/238 (39%), Gaps = 23/238 (9%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++I+ I+D H   +              +  ++ I   + +  L+V TGDL+     +  
Sbjct: 1   MKIVHISDLHFGEEL--------VRSKVEKAIKQINEIEPD--LVVVTGDLSCWGIHSEL 50

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
           +   E +   ++    +PGNHD +        +      K+++   +  I+ +DS    +
Sbjct: 51  REAYEALEKLKSDYFVVPGNHDARNNGIEFF-ELYFGERKKIYKDSEVVIIGVDSTQPDI 109

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
             G +   Q  W+E       +R  +L LHHH +P   +  +++ L +AGE+  +L    
Sbjct: 110 DDGYIGFEQRRWIEENFRK--DRINVLALHHHIVPIPDTGRERNVLIDAGEVVEMLINL- 166

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAP-GWRTLELHAD 251
               +L GH H    +      ++   S          +F +  +    +  +EL  D
Sbjct: 167 GFALVLAGHRHMPYSIRLMRTHIIHAGS--------LGSFKILGMPDHNYNVIELSED 216


>UniRef50_B4D428 Metallophosphoesterase n=1 Tax=Chthoniobacter flavus Ellin428
           RepID=B4D428_9BACT
          Length = 303

 Score =  156 bits (395), Expect = 8e-37,   Method: Composition-based stats.
 Identities = 59/244 (24%), Positives = 94/244 (38%), Gaps = 22/244 (9%)

Query: 20  ITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLA-QDQSSAAYQHFA 78
           ++DTH+ A    A   VN  +  +  +  +R        ++  GD A     +  Y  F 
Sbjct: 45  LSDTHVAADATLARFDVNMADHLRNAVAGVRALSSPPAGVIVNGDCAFNHGLAEDYATFT 104

Query: 79  EGIASF---RAPCVWLPGNHDFQPAMYSALQDAGISPAK------RVFIGEQWQILLLDS 129
             +        P     GNHD +   ++A++DA  +P         +         +LDS
Sbjct: 105 GLLHPLSEAGLPLHLSLGNHDDREVFWNAIKDARQTPPPLASRQVSIVEAGHANWFMLDS 164

Query: 130 Q-VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
             V     G L + Q  WL + L    ++  L+++HH P+        +  L +  EL  
Sbjct: 165 LDVTNKTPGVLGDEQRAWLSKALDARTDKPALVVVHHDPMLIEGK---KTGLLDTAELLA 221

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLEL 248
           +L    HVK L+ GH H     D +G  L+  P+    FK             GW   +L
Sbjct: 222 ILKPRSHVKALIFGHTHTWRLTDHDGLHLVNLPAVGYPFKKEEVT--------GWVDCQL 273

Query: 249 HADG 252
            ADG
Sbjct: 274 RADG 277


>UniRef50_A1ZMS0 Putative uncharacterized protein n=1 Tax=Microscilla marina ATCC
           23134 RepID=A1ZMS0_9SPHI
          Length = 221

 Score =  155 bits (391), Expect = 2e-36,   Method: Composition-based stats.
 Identities = 55/250 (22%), Positives = 106/250 (42%), Gaps = 30/250 (12%)

Query: 12  EARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
           +  +RI+QITD +L A  H     V   + ++ +L  I    H  DL++ T ++ Q + +
Sbjct: 2   DDTIRIVQITDPYLLANIH--YPEVLPIQVFENILTHINLLPHPPDLLILTSEVLQQRRN 59

Query: 72  AAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQV 131
              +     +     P  W+                         F  +    ++L+S  
Sbjct: 60  DTLR----LLQRLDIPFYWVAHE------------------QNASFNVKGTHFIMLNSCS 97

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
                G L    L++L+  L ++     ++ L HHPL        + +L++AG+  ++L 
Sbjct: 98  KNHSQGYLGNDTLDFLQNDLENSWAYPCIVTLRHHPLAIRTLTPPKDTLKDAGQFLSILD 157

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHAD 251
           +F H+K +L GHIH +  L+ N     A+P+ C    P   N     +   +R L+L ++
Sbjct: 158 QFYHIKAVLFGHIHHDFMLERNDIWFFASPAIC----PISPNNP--AVVFQYRLLDLTSE 211

Query: 252 GTLTTEVHRL 261
           G +   + ++
Sbjct: 212 GEVEVSLMKV 221


>UniRef50_O27755 Transcriptional regulator Icc related protein n=1
           Tax=Methanothermobacter thermautotrophicus str. Delta H
           RepID=O27755_METTH
          Length = 262

 Score =  154 bits (390), Expect = 3e-36,   Method: Composition-based stats.
 Identities = 50/202 (24%), Positives = 87/202 (43%), Gaps = 14/202 (6%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           +I QI+D H   +     L  N     +             DLI+ +GDL  +  S  Y+
Sbjct: 4   KIAQISDVHFGEKNFSDQLRKNLLHQLE---------NENPDLIIVSGDLTTEGYSHEYE 54

Query: 76  HFAEGIASFRA--PCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFG 133
             A  +   R       +PGNHD +       +   I   K V    ++ ++ LDS    
Sbjct: 55  LAAAFVDELRTITSTYTIPGNHDARNVGLIHFEKL-IGRRKFVHHDSEFAVIGLDSSEPD 113

Query: 134 VPHGELSEFQLEWLERKLADAPERH-TLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
           +  G++   QL+WL ++L   P+    ++  HHH LP   +  +++ L ++G+L  +L +
Sbjct: 114 INDGQIGMDQLDWLRKELERVPDHLCKIVTFHHHLLPIPNTGRERNILLDSGDLLKLLKE 173

Query: 193 FPHVKYLLCGHIHQELDLDWNG 214
           +  V ++L GH H        G
Sbjct: 174 Y-GVDFVLNGHKHVPNVWMIEG 194


>UniRef50_C7PKP5 Metallophosphoesterase n=1 Tax=Chitinophaga pinensis DSM 2588
           RepID=C7PKP5_CHIPD
          Length = 303

 Score =  153 bits (386), Expect = 7e-36,   Method: Composition-based stats.
 Identities = 60/282 (21%), Positives = 109/282 (38%), Gaps = 46/282 (16%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
             +  +R+  ITD HL+ +           + ++  L  I+  Q + D+I+  GD+  D 
Sbjct: 29  EKKPVLRVAHITDVHLYDKAGAP-------DFFRKCLHHIQSQQPKVDMILNGGDIVFDM 81

Query: 70  SSA-------AYQHFAEGIAS-FRAPCVWLPGNHDF--------QPAM--YSALQDAGIS 111
           +          ++     +      P  +  GNHD         Q       +L    ++
Sbjct: 82  NKENLSTIDVQWKLLHTIMKEECSLPVHYALGNHDIWWSENNKGQAVYGKQYSLDQLQLN 141

Query: 112 PAKRVFIGEQWQILLLDSQVFGVPH----GELSEFQLEWLERKLADAPERHTLLLLHHHP 167
                F    W+ ++LDS    V      G+L E Q+ WL  +L     +  + +L H P
Sbjct: 142 SPYYSFTKGGWKFIVLDSVHLDVDDTWYIGKLGEAQMIWLSDELKATDAQTPVCVLSHIP 201

Query: 168 LPAGCSWLDQHSLRNAGELD------------TVLAKFPHVKYLLCGHIHQELDLDWNGR 215
           +    + + Q ++ N  E+              +  ++P+VK  L GHIH +  + +N  
Sbjct: 202 ILT-ATLMVQDNIVNRWEMLGGDMHTDTADIIRLFYQYPNVKLCLSGHIHLKDKVVYNNV 260

Query: 216 RLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTE 257
             L   +    +    +       APG+  LEL ADG+ T +
Sbjct: 261 AYLCDGAVSGAWWKGNNR----ETAPGYGLLELFADGSFTEK 298


>UniRef50_B9TAV3 Putative uncharacterized protein n=1 Tax=Ricinus communis
           RepID=B9TAV3_RICCO
          Length = 279

 Score =  153 bits (386), Expect = 9e-36,   Method: Composition-based stats.
 Identities = 53/215 (24%), Positives = 87/215 (40%), Gaps = 15/215 (6%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + I QI+D H  +  ++++  ++   S+ AVL        + DL+V +GDL        Y
Sbjct: 37  MLIAQISDIH-ASPTNDSMARLDRAVSWLAVL--------QPDLLVVSGDLVDGNWLEGY 87

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDA---GISPAKRVFIG-EQWQILLLDSQ 130
              +  +       + LPGN D +  M + +         PA           I+ +D+ 
Sbjct: 88  GLISTSLHRLACRSLILPGNSDDRAVMRTIMPQPDYWHDRPAMHFIEPCGGSVIIGVDTC 147

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
           V G  +G+++   L WL R LA +P    LL  HHH  P G   LD    +    L  +L
Sbjct: 148 VDGEAYGDVT-QHLSWLRRALAGSPNGTALLFTHHHVFPCGIPPLDAVMCKGTQALAGLL 206

Query: 191 AKFPH-VKYLLCGHIHQELDLDWNGRRLLATPSTC 224
                    +  GH+H+ +   + G       S C
Sbjct: 207 KSGIRPPAAICSGHVHRSMSSLFAGIPAYTCGSIC 241


>UniRef50_A9A2N5 Metallophosphoesterase n=4 Tax=marine archaeal group 1
           RepID=A9A2N5_NITMS
          Length = 252

 Score =  153 bits (386), Expect = 9e-36,   Method: Composition-based stats.
 Identities = 52/264 (19%), Positives = 106/264 (40%), Gaps = 25/264 (9%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + I+QI+D H+ +Q  E        E +  ++  +     +   IV TGDL  +     Y
Sbjct: 1   MIIVQISDLHIGSQFLE--------EKFDVLVSEVNELNPDV--IVITGDLTNEGLMKEY 50

Query: 75  QHFAEGIASFR-APCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILL-LDSQVF 132
           +     +  F     + + GNHD++   Y  L      P + V   +   +L+ + +   
Sbjct: 51  EKCKSLLEKFNTKKIIAISGNHDYRNTGY--LLFKKFFPFQTVNELDNDVVLVTVGTARP 108

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
               GE+   Q  WLER +    ++  ++ +HHH +    +  DQ ++ +AG++   +  
Sbjct: 109 DRNEGEVGYRQNLWLERTMKKYKDKIKIVAMHHHLIAIPDTGSDQLTVVDAGDVLRTVLD 168

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATP-STCVQFKPHCSNFTLDTIAPGWRTLELHAD 251
              V  +LCGH H+    ++    ++    +T  + +    N         +  L +  D
Sbjct: 169 -SEVDVVLCGHKHRPWAWNFGTLTVVNAGTATSERVRGLFENT--------YNILTIK-D 218

Query: 252 GTLTTEVHRLADTRFQPDTASEGY 275
             +  ++  +   R   D   + Y
Sbjct: 219 KQVNVDLKIVGGKRVPIDEIVKNY 242


>UniRef50_C6B6U2 Metallophosphoesterase n=2 Tax=Rhizobium leguminosarum
           RepID=C6B6U2_RHILS
          Length = 250

 Score =  152 bits (384), Expect = 1e-35,   Method: Composition-based stats.
 Identities = 71/257 (27%), Positives = 99/257 (38%), Gaps = 22/257 (8%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + + QI+D H        L  + T E     L+  R      D++V TGDL  DQ    Y
Sbjct: 1   MLVAQISDIHAGPD----LSSLRTLERAIGWLKTFR-----PDVLVVTGDLVNDQWRHGY 51

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAG-----ISPAKRVFIGEQWQILLLDS 129
           +  AE + S   P   LPGN D    M S L   G       P       +   +  +D 
Sbjct: 52  RLVAENLRSLDCPVHLLPGNGDDVQLMRSELVAVGTWINATGPMHFRTAVDGLTLFGVDV 111

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
            V G  +G++    L WL   LAD     +LL +H  PL  G   LDQ   RN   L + 
Sbjct: 112 TVAGQSYGDVLP-HLPWLTSALADVT-TPSLLFMHQPPLRIGIEVLDQVGCRNGSALLST 169

Query: 190 LAK-FPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDT---IAPGWRT 245
           L         +LCGH+H+          +    S C    P   +   D     AP +  
Sbjct: 170 LETMHRLPLAILCGHVHRPAFGRLGSMTVQTCGSLCPP-NPLLLDGRADLSVIDAPSFLM 228

Query: 246 LELHADGTLTTEVHRLA 262
            E+ +DG L + V  + 
Sbjct: 229 HEV-SDGRLVSHVVSVP 244


>UniRef50_O30241 LacZ expression regulatory protein (Icc) n=1 Tax=Archaeoglobus
           fulgidus RepID=O30241_ARCFU
          Length = 372

 Score =  151 bits (383), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 55/254 (21%), Positives = 103/254 (40%), Gaps = 22/254 (8%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +RI+ I+D H      E +      E  +  +  I   + +  L+V TGDL+     +  
Sbjct: 1   MRIVHISDLHF---GEELIR-----EKVEKAVRQINEIEPD--LLVITGDLSCWGIHSEM 50

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
           +   E +   +   + +PGNHD +   Y   Q       K+ +  +   ++  DS    +
Sbjct: 51  RDAYETLLDLKPDYIAVPGNHDARNIGYEFFQ-LYFGETKKYWKNDVVSLIAADSTQPDL 109

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
             G + + Q +W+  K+    +R  +L LHHH  P   +  +++ L +AGE+  +L    
Sbjct: 110 DDGYIGKEQRDWIVSKIRK--DRFNILALHHHIAPIPKTGRERNVLIDAGEMVELLIA-N 166

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTL 254
            +  +L GH H    L      ++    T   FK       L      +  +E+  D TL
Sbjct: 167 GISAVLAGHRHMPYSLRLMRTHVIHA-GTLGSFK------VLGMPDHNYNVIEIK-DNTL 218

Query: 255 TTEVHRLADTRFQP 268
           T ++  +     + 
Sbjct: 219 TLKLRFVDYGEVEI 232


>UniRef50_Q3Y3L7 Metallophosphoesterase n=1 Tax=Enterococcus faecium DO
           RepID=Q3Y3L7_ENTFC
          Length = 267

 Score =  151 bits (382), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 57/263 (21%), Positives = 101/263 (38%), Gaps = 16/263 (6%)

Query: 15  VRILQITDTHLFAQKHEALLGVN---TWESYQAVLEAIRPHQHE--FDLIVATGDLAQDQ 69
           +R L ++D H        L       T ++ Q  LE +        +D I+ TGDL  + 
Sbjct: 1   MRFLHLSDIHFRENYQTNLFTAELFPTIKNPQLALEKLLQELSLTVYDFILLTGDLVHEG 60

Query: 70  SSAAYQHFAEGIASF--RAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE--QWQIL 125
             + YQ   + +  +    P  +  GNHD +   +  +        + +        +I+
Sbjct: 61  GISDYQVLRKMLDQYFPTTPYYFCRGNHDRRSVFFEGMSVESNETGEYIHCTNQNGLRII 120

Query: 126 LLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGE 185
            LDS       G++S  Q+  L+  L    E+ T+LL+HH       SW D   +    E
Sbjct: 121 SLDSAQDTQHEGKISIGQMIQLQEWLGTPAEKGTILLVHHPL-----SWEDPSIVTEVPE 175

Query: 186 LDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRT 245
               L     +  +  GHIHQ    ++  ++     S       +  +++L T   G+ +
Sbjct: 176 GFAELIAESDILGIFVGHIHQGSSAEFADKKQFMAESLSFGVDEY-PDYSLFTNRTGFTS 234

Query: 246 LELHADGTLTTEVHRLADTRFQP 268
             L  DG + T  H L   + + 
Sbjct: 235 GSL-IDGKIFTYQHYLTPHQIEI 256


>UniRef50_C2KF95 Serine/threonine protein phosphatase family protein n=4
           Tax=Lactobacillus crispatus RepID=C2KF95_9LACO
          Length = 408

 Score =  151 bits (382), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 63/303 (20%), Positives = 112/303 (36%), Gaps = 56/303 (18%)

Query: 20  ITDTHLFAQ-----------KHEALLGVNTWESYQAVLEAIRPH-QHEFDLIVATGDLAQ 67
           ++DTHL A                  G +      A+   +R   Q +   ++ TGD+  
Sbjct: 13  LSDTHLIADSLHDDGLAFQHMRNTSAGKDLDYQEIALTAFVRKVIQEKPTAVIITGDVTF 72

Query: 68  DQSSAAYQHFAEGIASF---RAPCVWLPGNHD---------------------------- 96
           + +  + +  A         +   + LPGNHD                            
Sbjct: 73  NGAKISGERLANIFKPLTKNKIAFLVLPGNHDIFDGWARKFKGDHEDYTPQISPAIWKEI 132

Query: 97  FQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV--------PHGELSEFQLEWLE 148
           F  + + AL +   S A  V + +Q++++L DS ++G          +G +SE Q+ W+E
Sbjct: 133 FADSYHYALHEDPDSLAYSVNLNKQYRLILADSNIYGKQESQTHLITNGRISESQMNWIE 192

Query: 149 RKL--ADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIH- 205
           ++L  A   ++  L  +HH+           + L NA  L  +L K+ +VK +  GH+H 
Sbjct: 193 KELIDAQQKQQQVLFFMHHNLYRHNKVIYQGYILDNALALQGLLQKY-NVKAVFSGHMHA 251

Query: 206 QELDLDWNGRRLLATPSTCV-QFKPHCSNFTLDTIAPGWRTLELHADGTLTTEVHRLADT 264
           Q +   +  R +      C    K       LD     ++      +  LT E  +   T
Sbjct: 252 QNIIGPFANRPIAEVAGACFCMTKQEYGQLYLDEAGMQYQVHSFKMESWLTAEEKQKVPT 311

Query: 265 RFQ 267
            F 
Sbjct: 312 DFS 314


>UniRef50_C2FYP3 Metallophosphoesterase n=1 Tax=Sphingobacterium spiritivorum ATCC
           33300 RepID=C2FYP3_9SPHI
          Length = 317

 Score =  151 bits (381), Expect = 3e-35,   Method: Composition-based stats.
 Identities = 56/284 (19%), Positives = 104/284 (36%), Gaps = 55/284 (19%)

Query: 12  EARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
           +  +RI  +TD H+  +           ++   +   ++  + + D I+ TGD   D ++
Sbjct: 39  KRSLRIAHLTDIHILDKPE-------VSKAVAGIYTQLQSMKDKPDFIINTGDSLMDMNN 91

Query: 72  AAYQHFAEGIASFR-------APCVWLPGNHDF--------------QPAMYS---ALQD 107
              +       ++               GNHD               +  +Y    A+  
Sbjct: 92  QTKERIDTLWKAWDHAAATHSFAVKSCLGNHDVWYLPKEHAAYEQSSKDPLYGKKWAMTK 151

Query: 108 AGISPAKRVFIGEQWQILLLDSQVFGVPHG--ELSEFQLEWLERKLADAPERHTLLLLHH 165
            G+  A   F  + W+ + LDS  +    G     + QL+WL  +LA    +  ++L  H
Sbjct: 152 LGLPQAYYSFEQKGWKFIALDSINYNSEKGGYTFGQEQLDWLTEELAQTSGKTPVVLFSH 211

Query: 166 HP----------------LPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELD 209
            P                L  G    DQH   +   + ++L + P+V+  L GH+H    
Sbjct: 212 VPIISVTPLLYAAQRTPILKMGFPGGDQHV--DVMAVKSILKQHPNVRVALSGHVHYVDH 269

Query: 210 LDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGT 253
           + + G       +    +     N  LD  AP +  L+L+ DG+
Sbjct: 270 VAYLGVNYYCGGAVSGNWW----NGVLDDFAPAYSILDLYEDGS 309


>UniRef50_Q1AVF9 Metallophosphoesterase n=1 Tax=Rubrobacter xylanophilus DSM 9941
           RepID=Q1AVF9_RUBXD
          Length = 274

 Score =  150 bits (379), Expect = 5e-35,   Method: Composition-based stats.
 Identities = 53/269 (19%), Positives = 99/269 (36%), Gaps = 25/269 (9%)

Query: 9   LAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQD 68
           ++ + R+ I QI+D H  +      L        +  +  I     +   +V +GDL   
Sbjct: 1   MSTQGRLTICQISDIHCGSPYFIPDL-------LERSILEINDL--DPTAVVVSGDLTNA 51

Query: 69  QSSAAYQHFAEGIASFRAP-CVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLL 127
                Y+  AE I  FR    + +PGNHD +   Y   +         V   E   ++ +
Sbjct: 52  GYRQEYEQAAEYIRRFRCEHLMVIPGNHDSRNVGYVHFERL-FGERYSVIDFEDAIMVGV 110

Query: 128 DSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELD 187
           DS    +  G +      ++    A A E+  + ++HHH +P   +  +++ + +AG++ 
Sbjct: 111 DSSEPDLNDGRVGREHYGFIHESFAGAEEKLKIFVVHHHLIPIPGTGRERNIVFDAGDVL 170

Query: 188 TVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLE 247
            +LA    V  +L GH H            +    T        +        P +  +E
Sbjct: 171 ELLAD-TEVDLVLSGHKHVPYSWRLENM-FIVNAGTA------STTRLRGNTRPCYNIIE 222

Query: 248 LHADGTLTTEVHRLADTRFQ---PDTASE 273
           +  +      V R    R +    D  +E
Sbjct: 223 VENE---RVRVFRKYPFRERELVVDFNAE 248


>UniRef50_B5JMC7 Ser/Thr protein phosphatase family protein n=1 Tax=Verrucomicrobiae
           bacterium DG1235 RepID=B5JMC7_9BACT
          Length = 309

 Score =  149 bits (378), Expect = 6e-35,   Method: Composition-based stats.
 Identities = 56/284 (19%), Positives = 103/284 (36%), Gaps = 49/284 (17%)

Query: 12  EARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ-- 69
           +  +RI  +TD H+   K       +  E     ++  +    + DLI+  GD   D   
Sbjct: 30  KRSLRIAHLTDIHVMPDK-------DAPEKMARAIQHAQSQTDKPDLILNGGDCIMDALK 82

Query: 70  -----SSAAYQHFAEGIA-SFRAPCVWLPGNHDF---------QPAMYS---ALQDAGIS 111
                + A +  +   +      P     GNHD          +   Y    A+++  + 
Sbjct: 83  RSKSETKAQWSEWHGVLKNELELPFYSAIGNHDIWGWALPNSKKNVSYGKQWAMEELALK 142

Query: 112 PAKRVFIGEQWQILLLDSQV--FGVPHGE---LSEFQLEWLERKLADAPERHTLLLLHHH 166
                F    WQ ++LDS         G    L E Q  WL + LA++  +  + +L H 
Sbjct: 143 QRYYSFEKNNWQFIVLDSSHFEPSFKSGYTAKLDEAQFAWLAQTLAESDPKKPICILSHI 202

Query: 167 PLPAGCSWLDQHSLR-------------NAGELDTVLAKFPHVKYLLCGHIHQELDLDWN 213
           P+ + C + D  + +             +A  +  + A+ P+VK  L GHIH    + + 
Sbjct: 203 PIISFCPFFDGDNEKSGDWQVPGPWMHIDARRIKDLFAQHPNVKLALSGHIHLRDQVRYL 262

Query: 214 GRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTE 257
           G   L   +    +               +  ++L+ DGT  ++
Sbjct: 263 GIDYLCNGAVSGGWWDGPYQ----EFPSAYVLVDLYEDGTSQSQ 302


>UniRef50_D1N465 Metallophosphoesterase n=1 Tax=Victivallis vadensis ATCC BAA-548
           RepID=D1N465_9BACT
          Length = 608

 Score =  148 bits (375), Expect = 2e-34,   Method: Composition-based stats.
 Identities = 55/254 (21%), Positives = 103/254 (40%), Gaps = 32/254 (12%)

Query: 13  ARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA 72
           A +++  ++D H+         G    +  Q  +  I     +   ++ TGDL+   ++A
Sbjct: 20  AELKVAILSDIHVSP-------GNPNEQRLQQAIAEINESDVDQ--VIVTGDLSNRGATA 70

Query: 73  AYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV-FIGEQWQILLLDSQV 131
                 E +     P   LPGNH+   +   AL  A +  ++R  F      ++   +  
Sbjct: 71  ELTRVKELLDQLNKPYRALPGNHETNWSDSGALAFAELFRSERFAFERNGVLLIGFSTGP 130

Query: 132 F-GVPHGELSEFQLEWLERKLAD-APERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
           +  +  G +    + +L+  LA+ A ++  +++  H+PL           L N  E+  V
Sbjct: 131 YLKMGDGHVRAEDIAFLKDTLAERAADQKPVIVFCHYPL--------ADELSNGVEVAEV 182

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELH 249
           LA + HV  L+CGH H +   +  G   +         +P  SN   D    G+  + ++
Sbjct: 183 LAPY-HVLGLVCGHTHVQFRRNIYGIDNIVC-------RPLTSN---DGKTFGYNFI-VY 230

Query: 250 ADGTLTTEVHRLAD 263
            +G L     RL D
Sbjct: 231 DNGKLEAWEKRLGD 244


>UniRef50_Q5UEX4 Predicted Ser/Thr protein phosphatase family protein n=1
           Tax=uncultured alpha proteobacterium EBAC2C11
           RepID=Q5UEX4_9PROT
          Length = 256

 Score =  148 bits (375), Expect = 2e-34,   Method: Composition-based stats.
 Identities = 50/265 (18%), Positives = 90/265 (33%), Gaps = 25/265 (9%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + + QI+DTHL         G     + +  +EAI       D+++ TGDL+ + SSA  
Sbjct: 1   MLVAQISDTHLITPGGPGRFGNEKLIALEKCIEAINNLDTLPDVVIHTGDLSDNGSSAEL 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQD-----AGISPAKRVFIGEQWQILLLDS 129
               + +     P    PGN D    +     +         P   +      ++  LD+
Sbjct: 61  LLAKKHLDKLVVPYYVTPGNKDCADKLIEVFTEQLSDVVTGGPITYLVDSLPIKLASLDT 120

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL--RNAGELD 187
                  G L   ++  +++ L+   +   ++  HH P          +     N+ +L 
Sbjct: 121 TTSLDNRGLLDFKKIAAIDKVLSMHQDDPVIIFSHHPPFNLSSENSPHYEFVSENSIKLF 180

Query: 188 -TVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFK--------PHCSNFTLDT 238
             ++ +   +  L CGH H+ +            P  C             H  NF L  
Sbjct: 181 DELVDRHAQIVALFCGHFHRPIRKSMGLFDANIAPPVCNLIDYSSTKTGPNHIGNFQLHN 240

Query: 239 IAPGWRTLELHADGTLTTEVHRLAD 263
              G+           TTEV  ++ 
Sbjct: 241 FGKGY---------EFTTEVKMISH 256


>UniRef50_Q2JP63 Ser/Thr protein phosphatase family protein n=2 Tax=Synechococcus
           RepID=Q2JP63_SYNJB
          Length = 309

 Score =  148 bits (375), Expect = 2e-34,   Method: Composition-based stats.
 Identities = 55/236 (23%), Positives = 83/236 (35%), Gaps = 30/236 (12%)

Query: 14  RVRILQITDTHLFAQ-KHEALLGVN-TWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
           R+   Q++D HL  +         +      +A +  +     +   +V TGDL      
Sbjct: 5   RICFAQVSDVHLMPETGCRCWWMSDSPRRQLEAAVAHLN-QVPDLHFVVFTGDLVDQADP 63

Query: 72  AAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSA----------------LQDAGISPAKR 115
            ++Q F E +A  R P     GNHD                        L  A       
Sbjct: 64  ESFQSFQEIVAQLRVPYYLSLGNHDIDTLRRKGRFNRDQFIRWCQSQFPLSLAPTGYVDY 123

Query: 116 VFI-GEQWQILLLDSQV--FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGC 172
                   +++ LD+ +  F +P G L   QL WL   L   PE   +LL+H  P  A  
Sbjct: 124 SLSPLPGIRLIALDASLGRFPLPQGVLRPSQLHWLGEHLQTVPEEWLILLIHQPPFIAP- 182

Query: 173 SWLDQHSLRN-------AGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATP 221
           + +D    R        A  L  +LA+   V  +L GH+H       +G   L  P
Sbjct: 183 TQMDAVLFRKYRLLSEPASALHALLARHGRVVAVLSGHLHVPKVYVRDGIPYLTAP 238


>UniRef50_B5YAA1 Membrane-associated protein, putative n=2 Tax=Dictyoglomus
           RepID=B5YAA1_DICT6
          Length = 252

 Score =  148 bits (374), Expect = 2e-34,   Method: Composition-based stats.
 Identities = 50/221 (22%), Positives = 93/221 (42%), Gaps = 12/221 (5%)

Query: 42  YQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHD-FQPA 100
           ++  L  I   + +   I+  GD+  + +   Y++  E + +   P   +PGNHD ++  
Sbjct: 41  FERNLSEILKRKPD--FIIQLGDILVEGTEKEYKYIGELLRNVNIPFYIVPGNHDLYKDP 98

Query: 101 MYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTL 160
                Q     P    F  E  + ++L++       G L + QLEWL   L +  +++  
Sbjct: 99  RGEKFQKFTGRPLYYYFDYENARFIILNNS-----SGILGKTQLEWLTNVLKENDKKYKF 153

Query: 161 LLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLAT 220
           + +H   +  G  +L   +     ++   L +   V Y+  GHIH     + NG   +  
Sbjct: 154 VFMHQPVISPGLFFLLHKADPVESKMLMKLFEEYKVNYVFSGHIHMYYRKEINGVVYII- 212

Query: 221 PSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTEVHRL 261
            S     +P+ S+  LD   P +  +E+   G +  EV RL
Sbjct: 213 -SGIGGARPYVSS-DLDEGKPHFVLMEVTDKG-IKEEVVRL 250


>UniRef50_C5EL28 Predicted protein n=1 Tax=Clostridiales bacterium 1_7_47FAA
           RepID=C5EL28_9FIRM
          Length = 288

 Score =  147 bits (372), Expect = 4e-34,   Method: Composition-based stats.
 Identities = 61/275 (22%), Positives = 94/275 (34%), Gaps = 39/275 (14%)

Query: 15  VRILQITDTHLFAQ---KHEALLG----------------------------VNTWESYQ 43
           + IL ++D H   +   + EA  G                             N      
Sbjct: 1   MYILHLSDIHYRRELGRRKEADRGRADGEDKQHESGGRLAGPDGYQAMLSAMQNPLVFLD 60

Query: 44  AVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASF--RAPCVWLPGNHDFQPAM 101
             L+         DL+V TGDL +D ++  Y+     I       P V   GNHD + + 
Sbjct: 61  DCLDRAARDWKTIDLVVITGDLTEDGTAEDYRCLKHHIRERVGDIPLVVTLGNHDNKRSF 120

Query: 102 YSA-LQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTL 160
               L++ G +P   +       ++  D+ V GVP G + + Q  WLER L       ++
Sbjct: 121 REGWLEEMGSAPYNTIRWVGGTAVIAFDTSVQGVPDGRMDDRQAAWLERALDAVGRNPSI 180

Query: 161 LLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLAT 220
           L+ HHH LP          L  +G+L +++     V  +LCGH H        GR     
Sbjct: 181 LVTHHHLLPEQGQIP---PLPESGKLLSLIGN-SGVCLILCGHTHHHHAGQAAGRPCHVA 236

Query: 221 PSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLT 255
            S                   G+       DG + 
Sbjct: 237 DSLSFCGDDMGGGQVRFQEKYGFNVYR-MEDGMVR 270


>UniRef50_Q1C384 Regulator of lacZ n=8 Tax=Enterobacteriaceae RepID=Q1C384_YERPA
          Length = 137

 Score =  147 bits (372), Expect = 4e-34,   Method: Composition-based stats.
 Identities = 82/114 (71%), Positives = 94/114 (82%)

Query: 1   MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV 60
           MESL  LP+A  ARVRILQITDTHLFA +HE LLGVNT+ SY+AVL+AI   QH FDL+V
Sbjct: 1   MESLFKLPMASGARVRILQITDTHLFAGEHETLLGVNTFHSYRAVLDAIIAEQHPFDLVV 60

Query: 61  ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAK 114
           ATGDLAQD S AAYQ+FA+GI+    PCVWLPGNHDFQPAM+ AL +AGI+P K
Sbjct: 61  ATGDLAQDHSVAAYQNFAKGISRLPVPCVWLPGNHDFQPAMFDALAEAGIAPFK 114


>UniRef50_B9XC60 Metallophosphoesterase n=1 Tax=bacterium Ellin514
           RepID=B9XC60_9BACT
          Length = 303

 Score =  146 bits (369), Expect = 7e-34,   Method: Composition-based stats.
 Identities = 64/247 (25%), Positives = 101/247 (40%), Gaps = 27/247 (10%)

Query: 20  ITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLA-QDQSSAAYQHFA 78
           ++D HL A + +   G+N  +++  V   +   +     ++ +GDLA     SA Y    
Sbjct: 45  VSDIHLAADRKKLGRGINMADNFTQVTTQLLDPKWRHSAMLISGDLAFNSGESADYATVT 104

Query: 79  EGIASFR---APCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQIL--------LL 127
           E +   +    P     GNHD +   + A+ +A    AKR     Q  +L        +L
Sbjct: 105 ELLQPVQAGGIPIHLTLGNHDNREHFWDAIAEA--KAAKRPVTDHQVSLLRSSRANWFVL 162

Query: 128 DSQVFG-VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGEL 186
           DS        G + E QL+WL   L D   +  L+++HH+             L++  +L
Sbjct: 163 DSLEQTLATPGLIGEAQLDWLAHALDDNKRKPALIVVHHNLNDNSGK---PSGLKDGDKL 219

Query: 187 DTVLAKFPHVKYLLCGHIH-QELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRT 245
             ++    HVK LL GH H  E+  D +G  L+  P T   FK    N        GW  
Sbjct: 220 LDIIRPRKHVKALLYGHSHDWEVKQDSSGIHLINLPPTAYVFKEGKPN--------GWVH 271

Query: 246 LELHADG 252
             L + G
Sbjct: 272 ASLQSKG 278


>UniRef50_D2QD99 Metallophosphoesterase n=1 Tax=Spirosoma linguale DSM 74
           RepID=D2QD99_9SPHI
          Length = 306

 Score =  145 bits (367), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 56/276 (20%), Positives = 103/276 (37%), Gaps = 46/276 (16%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQS---- 70
           +R+  +TD H+          +   + ++  L  ++    + DLI+  GD   +      
Sbjct: 36  LRVAHLTDVHMQPI-------IGAAKGFEKCLHHVQSLPDKPDLIINGGDAVMEAHGRGK 88

Query: 71  ---SAAYQHFAEGIASFRA-PCVWLPGNHD----------FQPAMYSALQDAGISPAKRV 116
              S  ++ + + + S  A P +   GNHD          F+     A+ +  ++     
Sbjct: 89  DSVSRQWRLYQDVLRSENALPVISCVGNHDIWCKQETKICFEAGRQWAMDEFQMAKRFYS 148

Query: 117 FIGEQWQILLLDSQVFGVPH----GELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGC 172
                W+I++LDS             L + Q  WLE +L   P    +L++ H P+ A C
Sbjct: 149 IDRNGWRIIMLDSVQPKADGSWYTAHLDDEQYHWLEAELKSTPNTTPILVVSHIPILAAC 208

Query: 173 SWLDQHSLRNAG-------------ELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLA 219
            + D     +                L  +    P+VK  L GHIH    +D+NG     
Sbjct: 209 VFFDGPRFSDENWSVPARWMHSDTVRLTNLFHNHPNVKAALSGHIHLTDRVDYNGVSYYC 268

Query: 220 TPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLT 255
             +    +     +      A G+  ++L+ DGT+ 
Sbjct: 269 NGAVSGAWWFGKYH----HTAAGYALVDLYDDGTVQ 300


>UniRef50_C1VB71 Predicted phosphohydrolase n=1 Tax=Halogeometricum borinquense DSM
           11551 RepID=C1VB71_9EURY
          Length = 344

 Score =  145 bits (366), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 55/234 (23%), Positives = 89/234 (38%), Gaps = 24/234 (10%)

Query: 10  AGEARVRILQITDTHLFAQKHEA-LLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQD 68
               R RI  ++D HL         +   T    +A + AI     +  L +  GDL +D
Sbjct: 31  TSHTRTRIAVVSDPHLTPTATGTWKVYHRTETRLRAAIAAINDLNVDATLSL--GDLTRD 88

Query: 69  QSSAAYQHFAEGIASFRAPCVWLPGNHDFQ----PAMYSALQDAGISPAKRVF----IGE 120
                +    E +A    P V +PGNHD            + + G   A+  F       
Sbjct: 89  GHPEEFDCVDELLADLDTPFVSVPGNHDVPKQWDDYEAPTVDEFGARYARGAFPFHVSVG 148

Query: 121 QWQILLLDS-----QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHH---HPLPAGC 172
              ++ LD+      ++    G +    + WL+  L++      ++  HH   HP     
Sbjct: 149 GVDLIGLDTASGDGTLYDSHEGLVPSEHVAWLDETLSEVES--PIVASHHNVFHPREHTG 206

Query: 173 SWLDQ--HSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTC 224
            + D+  + LRNA E+  VL+       +L GHIH        G R +  P+TC
Sbjct: 207 QFADEDFYQLRNADEVVEVLSSGGDP-LVLSGHIHWPATARRGGVREIIAPATC 259


>UniRef50_UPI0001745388 Ser/Thr protein phosphatase family protein n=1 Tax=Verrucomicrobium
           spinosum DSM 4136 RepID=UPI0001745388
          Length = 302

 Score =  143 bits (362), Expect = 5e-33,   Method: Composition-based stats.
 Identities = 61/259 (23%), Positives = 95/259 (36%), Gaps = 21/259 (8%)

Query: 21  TDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQ-DQSSAAYQHFAE 79
           +DTH+ A       GV    + ++ +  +         ++ +GD A      A YQ    
Sbjct: 47  SDTHIDADPLAVSRGVTMAANLRSCVAEVLARAERPAGLILSGDCAHLKGMRADYQTLKP 106

Query: 80  GIASF---RAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFI----GEQWQILLLDSQ-V 131
            +      + P   L GNHD + A+   L  A        F+           LLDS   
Sbjct: 107 LLQPLVAAKLPVHLLMGNHDDRVAVTEVLDCATSPAVPSRFVSVQETPHANWFLLDSLDK 166

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
                G L   QL WL R+L    +R  ++++HH+            +L ++  L  +L 
Sbjct: 167 VNSTPGVLGGEQLAWLGRELDARSDRPAVIVVHHNITLQESK---TDALLDSTSLLELLR 223

Query: 192 KFPHVKYLLCGHIHQ-ELDLDWNGRRLLATPSTCVQFKPHCSN-FTLDTIAPGWRTLELH 249
               VK  + GH H+     D +G   +  P     FK    N + L T+ P    LEL 
Sbjct: 224 PRRQVKACIYGHTHRWSHTEDESGLHFINLPPVAYVFKQEFPNGWVLATLQPDALRLELR 283

Query: 250 A-------DGTLTTEVHRL 261
           A        G + T   R+
Sbjct: 284 ALDANHPQHGEVKTLKWRV 302


>UniRef50_C7Q3U3 Metallophosphoesterase n=3 Tax=Actinomycetales RepID=C7Q3U3_CATAD
          Length = 247

 Score =  143 bits (362), Expect = 5e-33,   Method: Composition-based stats.
 Identities = 57/213 (26%), Positives = 90/213 (42%), Gaps = 11/213 (5%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
            V I  ++D H+ A       G    E  + V + +     + DL+V TGD+A     + 
Sbjct: 2   PVVIAHVSDIHIDA-------GPRAAERTRRVFDHLDALPADLDLVVLTGDIADHGLDSE 54

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQD--AGISPAKRVFIGEQWQILLLDSQV 131
           Y+   +  A+ R P +  PGNHD + A   AL    A   P  +V   +++ + L DS +
Sbjct: 55  YETVRQATAT-RHPLLVCPGNHDDREAFRRALLGVPASTGPINQVHRTDRFVVALCDSSI 113

Query: 132 FGVPHGELSEFQLEWLERKLADAPER-HTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
                G L++  L WL  +L   P+    L+  HH P+     ++D+        L   +
Sbjct: 114 PKQDDGFLADETLAWLAAELDATPDGVPVLIGFHHPPVELHTPFVDKIRQFGEERLAEAV 173

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPST 223
           A   +V  LL GH H      + G  LL  P  
Sbjct: 174 AGRQNVVALLAGHAHTAAATHFAGLPLLVAPGV 206


>UniRef50_D2QP98 Metallophosphoesterase n=1 Tax=Spirosoma linguale DSM 74
           RepID=D2QP98_9SPHI
          Length = 304

 Score =  143 bits (362), Expect = 5e-33,   Method: Composition-based stats.
 Identities = 59/282 (20%), Positives = 104/282 (36%), Gaps = 45/282 (15%)

Query: 9   LAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQD 68
           LA +  VR   + DTH+              E        ++    +   I+  GD+  D
Sbjct: 26  LARKRSVRFAYLGDTHITPDAK-------PVERIAKCFHHVQNQADKPSFILHGGDVIMD 78

Query: 69  QSSAAYQHFAEGIASFR--------APCVWLPGNHDF-------QPAMYS---ALQDAGI 110
             +   Q   +   ++          P  +  GNHD           +Y    A+    I
Sbjct: 79  ALAEDRQKVQQQWDAWNGLVKADNSLPIEYCIGNHDIWGFENAKNDLLYGKKWAIDQMKI 138

Query: 111 SPAKRVFIGEQWQILLLDSQVFGVPH----GELSEFQLEWLERKLADAPERHTLLLLHHH 166
           S   R F    W  ++LDS           G +   Q++WL+  LA    +  +L+L H 
Sbjct: 139 SGRYRSFDRNGWHFIVLDSVQPKPDGKWYTGNIDAEQMDWLKADLAKTNPKTPILVLSHI 198

Query: 167 PLPAGCSWL-DQH------------SLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWN 213
           P+ +   +  D +             L N  +L  +  ++P+VK  L GH+H    +++N
Sbjct: 199 PIFSPTGFFSDTNVKDGNWTISAGTILANTPDLLKLFYQYPNVKAALSGHMHLLDRVEYN 258

Query: 214 GRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLT 255
           G   L   +    +    S+    T A G+   +L+ DG++ 
Sbjct: 259 GVAYLCNGAVSGNWWK--SDVYQQTKA-GYALFDLYDDGSVE 297


>UniRef50_B1LAV7 Metallophosphoesterase n=2 Tax=Thermotoga sp. RQ2
           RepID=B1LAV7_THESQ
          Length = 343

 Score =  140 bits (354), Expect = 4e-32,   Method: Composition-based stats.
 Identities = 43/188 (22%), Positives = 77/188 (40%), Gaps = 12/188 (6%)

Query: 37  NTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHD 96
           N+  ++  +++A+   Q      V TGD+  D S   ++ + E +  F+ P + +PGNHD
Sbjct: 49  NSISTFSKLIDAVNREQ-NAAFAVNTGDMVFDGSLFKWELYLEQLRRFKIPVLPVPGNHD 107

Query: 97  FQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPE 156
                 + L      P    F       ++L+          +  +QLEWL+++L  +  
Sbjct: 108 LADDPGNYL--KIFGPLYYSFHTGNSYFIVLN----NANEKYVDAYQLEWLKKELEKSQS 161

Query: 157 RHTLLLLHHHPLPAG----CSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDW 212
                +  H P+               L NA  L  +L ++ +V  +  GHIH     +W
Sbjct: 162 YRYRFVFMHVPVYDPRKEKQPGHSMKDLENAQTLLNILKEY-NVTMVFAGHIHGYFRGEW 220

Query: 213 NGRRLLAT 220
           NG   + T
Sbjct: 221 NGVSYIIT 228


>UniRef50_A4A1K6 Ser/Thr protein phosphatase family protein (Fragment) n=1
           Tax=Blastopirellula marina DSM 3645 RepID=A4A1K6_9PLAN
          Length = 269

 Score =  140 bits (353), Expect = 6e-32,   Method: Composition-based stats.
 Identities = 54/237 (22%), Positives = 88/237 (37%), Gaps = 22/237 (9%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQ-DQSSA 72
            + +  ++DTH+          VN   + Q  +  I     +   ++  GD A      A
Sbjct: 38  TMTLALLSDTHIPKNAEVTAREVNMTSNLQQGVREINQLPSKPAAVLFNGDCAYLSGLPA 97

Query: 73  AYQHFAEGIASF---RAPCVWLPGNHDFQPAMYSAL----QDAGISPAKRV--FIGEQWQ 123
            Y +FA+ I      +       GNHD  PA Y AL     +  +  +K V         
Sbjct: 98  DYANFAQCIQPLIDAQQELHMTMGNHDNIPAFYDALKTQRPEQPLVESKHVSILETPYVN 157

Query: 124 ILLLDS-QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHH------HPLPAGCSWLD 176
             LLDS     V  GEL + QL+WL  +L    ++  +++ HH       P   G +W  
Sbjct: 158 FFLLDSLMKTNVVTGELGDAQLKWLSDELDARADKPAIIMAHHTLQKVAPP--EGKAW-- 213

Query: 177 QHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSN 233
              + +  +   ++     VK  + GH H           L+  P++   F P   N
Sbjct: 214 -GGILDTAKFLELMHAKKQVKAYVFGHSHVWSHARDGDLHLINLPASAYVFNPTQPN 269


>UniRef50_Q46D43 3,5-cyclic-nucleotide phosphodiesterase n=8 Tax=Archaea
           RepID=Q46D43_METBF
          Length = 230

 Score =  139 bits (351), Expect = 8e-32,   Method: Composition-based stats.
 Identities = 46/181 (25%), Positives = 77/181 (42%), Gaps = 7/181 (3%)

Query: 45  VLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAP-CVWLPGNHDFQPAMYS 103
           +LE I     +   IV TGDL ++  +A Y    + I        V +PGNHD + A Y 
Sbjct: 8   MLENINRSSPDI--IVITGDLTENGLAAEYNGAKKFIDRIECKNKVIVPGNHDSRNAGYL 65

Query: 104 ALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLL 163
             +D   + +     GE   ++ LDS    +  G +      W+E   +       +  L
Sbjct: 66  FFEDLFKTRSTSGQFGE-ITVVGLDSSQPELDEGHIGRENYNWIENTFSVNG--FKVFAL 122

Query: 164 HHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPST 223
           HHH +P   +    + L +AG++  +L +   V  +LCGH H       N   +++  + 
Sbjct: 123 HHHLIPIPRTGRGNNVLVDAGDVLELLDR-SGVNLVLCGHWHIPWVWRLNDMLVISAGTV 181

Query: 224 C 224
           C
Sbjct: 182 C 182


>UniRef50_Q9YDE7 Putative uncharacterized protein n=1 Tax=Aeropyrum pernix
           RepID=Q9YDE7_AERPE
          Length = 724

 Score =  139 bits (351), Expect = 1e-31,   Method: Composition-based stats.
 Identities = 53/271 (19%), Positives = 100/271 (36%), Gaps = 43/271 (15%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEF--DLIVATGDLAQDQ-S 70
            + I+ +TD H  A     L  V     +   +  +   ++E   DL+V TGD++    +
Sbjct: 166 ELVIMHLTDIHFGAIDKGILNDV----KFARDVALVNTLKYELGLDLVVVTGDISDIGIN 221

Query: 71  SAAYQHFAEGIASFRAPCVWLPGNHDFQPA------MYSALQDAGISPAKRVFIGEQWQI 124
            ++Y+++A  +     P + +PGNHD+         +        +           +  
Sbjct: 222 VSSYRNWAFAMNQLLVPTMTVPGNHDWAQVPGLESFLLDFYGKYNVPARYWAAKWGNFLF 281

Query: 125 LLLDSQVFGVPHGELSEFQLEWLERKLADAPERHT--LLLLHHHPL-PAGCSWLDQHSLR 181
           + LDS       G +    L++LE  L+         ++L+HH      G    D  S R
Sbjct: 282 IGLDS----QSEGYVEPEGLDFLENVLSQYSGEDVVAIILVHHPIFSDPGRYKGDPESFR 337

Query: 182 NA------------GELDTVLAKFPHVKYLLCGHIHQELDLDW----NGRRLLATPSTCV 225
            A                 ++ ++  VK +  GHIH++ D  +    N      T +T +
Sbjct: 338 GALYGSWESKFELVERFFDIINRYDMVKVVFSGHIHRDADAIYFRQDNTPVYFITTTTAM 397

Query: 226 QFKPHCSNFTLDTIAPGWRTLELHADGTLTT 256
              P    +       G + + + ADG +  
Sbjct: 398 HGHPQGYFW-------GAKVVRVTADGQVEV 421


>UniRef50_B9TNQ0 Putative uncharacterized protein (Fragment) n=1 Tax=Ricinus
           communis RepID=B9TNQ0_RICCO
          Length = 257

 Score =  136 bits (344), Expect = 6e-31,   Method: Composition-based stats.
 Identities = 43/254 (16%), Positives = 92/254 (36%), Gaps = 37/254 (14%)

Query: 37  NTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA-------AYQHFAEGIA-SFRAPC 88
           +    +   L  ++    + D+++  GD+  D +          ++     +      P 
Sbjct: 4   DAPARFTRCLHHLQQQTPKVDMVLNGGDIVFDMNKENISTINDQWKLVQNIMKNECSLPV 63

Query: 89  VWLPGNHDF--------QPAM--YSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPH-- 136
            +  GNHD         Q       AL    +       +   W+I++LDS    + +  
Sbjct: 64  HYCLGNHDIWWYEDDKGQAIYGKKYALDKLQLVKPYYSLVKNGWKIIVLDSVHLDIDNTW 123

Query: 137 --GELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL-----------RNA 183
             G+L + QL WL  +L        ++++ H P+      ++   +            + 
Sbjct: 124 YIGKLGDEQLNWLSDELKATDANMPVMVMSHIPILTALLMIEDDIVNKWTMLGGDMHTDT 183

Query: 184 GELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGW 243
            ++  +  + P+VK  + GH+H    + +N    L   +    +            APG+
Sbjct: 184 AKIINLFYRHPNVKLCVSGHLHMRDKVVYNNVTYLCNGAVSGAWWEGNRR----ETAPGY 239

Query: 244 RTLELHADGTLTTE 257
             ++L+ADGT   +
Sbjct: 240 GLIDLYADGTFEEK 253


>UniRef50_C5PKR3 Putative uncharacterized protein n=2 Tax=Sphingobacterium
           spiritivorum RepID=C5PKR3_9SPHI
          Length = 627

 Score =  136 bits (344), Expect = 7e-31,   Method: Composition-based stats.
 Identities = 46/246 (18%), Positives = 90/246 (36%), Gaps = 32/246 (13%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           R   +TDTH+         G    +  +  ++ +   Q + D ++ +GD+ +  + A  +
Sbjct: 33  RFAHVTDTHVG--------GATGADDLRRTVKDLNAQQ-QLDFVILSGDITEFGADAELR 83

Query: 76  HFAEGIASFRAPCVWLPGNHD------FQPAMYSALQDAGISPAKRVFIGEQWQILLLDS 129
              + + S + P   +PGNHD                          F  + +  +  +S
Sbjct: 84  LAKQILDSLQLPWYVIPGNHDGNWSENGANTFRKVFGGETF-----FFRHKGYMFMGTNS 138

Query: 130 QVFGV-PHGELSEFQLEWLERKLADAPERHT-LLLLHHHPLPAGCSWLDQHSLRNAGELD 187
                   G++    L W++      P+  T L+ ++H+P           SL N  E  
Sbjct: 139 GPNMRMSPGQIPRENLVWMDSVFKANPDTQTPLIYINHYP--------QDSSLNNWFEAI 190

Query: 188 TVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLE 247
             + K  +V+   CGH H  +  +W G   +   S  ++ K     + + TI  G    +
Sbjct: 191 NRVKKR-NVQLAFCGHGHANVKYNWEGIPGIMGRSN-LRAKDSIGGYNIVTIGDGKAVYQ 248

Query: 248 LHADGT 253
           +   G 
Sbjct: 249 VKKPGQ 254


>UniRef50_C7NWB5 Metallophosphoesterase n=1 Tax=Halomicrobium mukohataei DSM 12286
           RepID=C7NWB5_HALMD
          Length = 312

 Score =  136 bits (343), Expect = 7e-31,   Method: Composition-based stats.
 Identities = 56/234 (23%), Positives = 93/234 (39%), Gaps = 31/234 (13%)

Query: 16  RILQITDTHL-FAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           R   + D H+   +   + L  +T +  +A +  I     + D +++ GDL +D     Y
Sbjct: 23  RFAVLADPHVSTRESGTSKLFEHTLDHLEAAVADIGRR--DVDAVLSPGDLTKDGEPWNY 80

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQ-------PAMYSALQDA-GISPAKRVFIGEQWQILL 126
               E ++    P   +PGNHD         P    A  D  G              ++ 
Sbjct: 81  DAVDEALSELDVPFYAVPGNHDVPKVRDEHDPLSVEAFADRYGPGELPYHAEVGGLDVIG 140

Query: 127 LDSQVFG-----VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHS-- 179
           L++            G ++E  L+WL+  LA+A    T ++L HH LP+    +D H   
Sbjct: 141 LNTAGTADRLYESHEGRVTEATLDWLDETLAEAE---TPVVLLHHNLPSVSDQIDAHREI 197

Query: 180 ---------LRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTC 224
                    + +A  L   LA     + LL GH H     +++G R +A P+TC
Sbjct: 198 EPEMVEIPAMADADPLAETLAD-GGAQLLLSGHYHLPATGEYHGLREIAAPTTC 250


>UniRef50_D1B7Z2 Metallophosphoesterase n=1 Tax=Thermanaerovibrio acidaminovorans
           DSM 6589 RepID=D1B7Z2_THEAS
          Length = 278

 Score =  135 bits (341), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 61/255 (23%), Positives = 105/255 (41%), Gaps = 33/255 (12%)

Query: 1   MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV 60
           ++S+L+ P+ GE  +R L + DT                  ++ ++  +R  Q     ++
Sbjct: 40  LDSILSTPVEGE--LRFLVVGDT------------RGPGSRFRFLVPQMREDQGL--FVI 83

Query: 61  ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE 120
             GDL    +   Y+   E + S R P + + GNH+         +D   S   R F+  
Sbjct: 84  HLGDLTNRGTQGEYREALELLRSIRKPFLVVIGNHELVDRGRGRFEDIFGSWRDRAFVLG 143

Query: 121 QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHH---PLPAGCSWLDQ 177
              ++LLD    G P   LSE +L WL+R+LA  P    ++ +H     P P     +D+
Sbjct: 144 GALLVLLD-NADGRP---LSEERLRWLDRELASHPG-PKMVFMHQPLFDPRPGKSHAMDE 198

Query: 178 HSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLAT---PSTCVQFKPHCS-- 232
              R A E+  VL +   V  +   H+H     DW+G     +    ++     P     
Sbjct: 199 ---RGAREMLEVLKRH-RVDRVFASHVHAFFQGDWDGVPYTISGGGGASLYSRDPESGFH 254

Query: 233 NFTLDTIAPGWRTLE 247
           ++   T+ PG   +E
Sbjct: 255 HYHRVTVGPGGVRVE 269


>UniRef50_A4WK20 Metallophosphoesterase n=5 Tax=Thermoproteaceae RepID=A4WK20_PYRAR
          Length = 641

 Score =  135 bits (341), Expect = 2e-30,   Method: Composition-based stats.
 Identities = 54/275 (19%), Positives = 99/275 (36%), Gaps = 51/275 (18%)

Query: 13  ARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQ-DQSS 71
             +RI+Q+TD H+  +       ++    Y+ +  A+      +D++  TGDLA      
Sbjct: 108 GPLRIIQLTDIHVGVE-------LDMASLYRLIHGALVASGGPYDVVFFTGDLADVGGQV 160

Query: 72  AAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQV 131
             Y  F +  A+   P   +PGNHD             +       +   + I+ LDS  
Sbjct: 161 WHYTLFTKYAATIPKPVFAIPGNHDHAGDDPLTNYQKFVGRPVWYRVIGPYLIIGLDSGF 220

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPA----------GCSWLDQHS-- 179
                G L + Q++  E  L   P++  ++L+HH P             G   +D+ +  
Sbjct: 221 ----DGYLRDDQVKMYEEVLKRYPDKVKIVLIHHPPFYLQDSYVVETYRGPQDVDRLNKD 276

Query: 180 --------------LRNAGELDTVLAK--FPHVKYLLCGHIH-QELDLDWNGRRLLATPS 222
                         L+N    +  L       V  ++ GH+H     +  NG   + T +
Sbjct: 277 PTGRRSYYIVYTSYLQNRPAFEKFLDLTIRYKVALVMAGHVHSGNSTIVINGTYFVTTRT 336

Query: 223 TCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTE 257
                            + G+RT  ++ DG +  +
Sbjct: 337 LGGSI----------DTSHGFRTYVVYPDGRVEVD 361


>UniRef50_C2E1N9 Serine/threonine protein phosphatase family protein n=8
           Tax=Lactobacillus jensenii RepID=C2E1N9_9LACO
          Length = 414

 Score =  134 bits (339), Expect = 2e-30,   Method: Composition-based stats.
 Identities = 59/303 (19%), Positives = 113/303 (37%), Gaps = 56/303 (18%)

Query: 4   LLTLPLAGEARVRILQITDTHL-----------FAQKHEALLGVNTWESYQAVLEAIRP- 51
           +L   L  +   +I  I+DTHL           F +     +G +     +A+L   R  
Sbjct: 1   MLKNLLTQKENPKIWVISDTHLIANELHDKGWAFQKMQNTSVGKDLHYQQKALLAFTRKV 60

Query: 52  HQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFR---APCVWLPGNHDFQP--------- 99
            + + D++V TGD+  +    + Q FAE  A  R      + LPGNHD            
Sbjct: 61  LKEKPDVVVVTGDITFNGERLSMQRFAEIFAPLRRHGIKLLVLPGNHDIYDGWARKFKDD 120

Query: 100 --------------------AMYSALQDAGISPAKRVFIGEQWQILLLDSQVFG------ 133
                               +   A ++ G S A  V +   ++++L DS ++       
Sbjct: 121 VQYRTDQVSPQDFKEIFYDSSYRYAAREDGSSLAYSVNLSPNYRLILADSNIYPMEYSLT 180

Query: 134 --VPHGELSEFQLEWLERKL--ADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
               HG + + +L ++E ++  A++  +H L  +HH+             L NA ++  +
Sbjct: 181 HPHTHGRIDDEELAFIEGQIIEAESNHQHVLFFMHHNLYRHNAVIYHNFVLDNASQVKRL 240

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCV-QFKPHCSNFTLDTIAPGWRTLEL 248
             K+ +V+ +  GHIH +              ++C           +L+     ++    
Sbjct: 241 FNKY-NVQAVFSGHIHAQSIKKAPDCSAYEVVTSCFSSTDQGYGEISLNDKQLCYKRYSF 299

Query: 249 HAD 251
           + D
Sbjct: 300 NMD 302


>UniRef50_Q64Z92 Serine/threonine protein kinase related protein n=12
           Tax=Bacteroidales RepID=Q64Z92_BACFR
          Length = 621

 Score =  133 bits (336), Expect = 5e-30,   Method: Composition-based stats.
 Identities = 46/267 (17%), Positives = 103/267 (38%), Gaps = 34/267 (12%)

Query: 4   LLTLPLAGEARV----RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLI 59
              LP+A  A+V    R  Q+TD HL     +        E  +  +E I       D +
Sbjct: 13  FFLLPVATRAQVTGSFRFAQLTDIHLNPNNPK------PTEDLKRSVEQINA-TPGVDFV 65

Query: 60  VATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQ--PAMYSALQDAGISPAKRVF 117
           + TGDL ++            +   +     +PGNH+ +   +  +A  +      +  F
Sbjct: 66  LVTGDLTEEGDRTTMLVVKSILDQLKVKYYVIPGNHETKWSDSGCTAFSEI-FGGERFKF 124

Query: 118 IGEQWQILLLDSQVFGV-PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLD 176
             + +  L  +S       +G +    + W+++++    +   ++L+ H+P+  G     
Sbjct: 125 EHKGFLFLGFNSGPLMRMAYGHVVPQDITWMKQEMDKVGKDKPVILVTHYPMQDG----- 179

Query: 177 QHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTL 236
              + N  ++   +  + +++  + GH H+   L ++G   + T S          N   
Sbjct: 180 --DVDNWYDVTDAVRPY-NIRTFIGGHYHRNRFLSYDGIPGILTRS----------NLRD 226

Query: 237 DTIAPGWRTLELHADGTLTTEVHRLAD 263
              + G+   ++  D ++ T   R+ +
Sbjct: 227 KNGSSGYSIFDITPD-SIITYEQRIDE 252


>UniRef50_A6WWL5 Metallophosphoesterase n=1 Tax=Ochrobactrum anthropi ATCC 49188
           RepID=A6WWL5_OCHA4
          Length = 271

 Score =  133 bits (334), Expect = 8e-30,   Method: Composition-based stats.
 Identities = 61/259 (23%), Positives = 90/259 (34%), Gaps = 23/259 (8%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS--A 72
           VR++QI+DTHL          V  W   +  L +         LI+ +GD++ D +    
Sbjct: 2   VRVIQISDTHL---GRHKAHFVENWRPLKNWLAS-----ENPKLIIHSGDISVDGADVED 53

Query: 73  AYQHFAEGIASFRAPCVWLPGNHD-------FQPAMYSALQDAGISPAKRVF--IGEQWQ 123
            +    E +    AP + +PGNHD        QPA    L+          +      W+
Sbjct: 54  DFAFCREVMVDLPAPMLVVPGNHDVGEPQSAHQPANEHRLERWNRQYGADFWAKDVGNWR 113

Query: 124 ILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNA 183
           +L  DS +         E Q  WLER++  A  R      H      G   +D       
Sbjct: 114 LLGFDSMILSSGLAA-EEAQFHWLERQMESADGRRIAWFTHQPLFINGWEDIDNGYWSVK 172

Query: 184 GELDTVLAKFPH---VKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA 240
            E  T L +      V  +  GH+H   D   +G + +  PS      PH          
Sbjct: 173 REPRTRLQRLTQRFGVDLIASGHLHLSHDFILDGVQFVWCPSAAFAVGPHMQPPLGGEKQ 232

Query: 241 PGWRTLELHADGTLTTEVH 259
            G    +    G   T VH
Sbjct: 233 LGAVRYDFSETGFSFTRVH 251


>UniRef50_B9K806 Metallophosphoesterase n=1 Tax=Thermotoga neapolitana DSM 4359
           RepID=B9K806_THENN
          Length = 355

 Score =  133 bits (334), Expect = 9e-30,   Method: Composition-based stats.
 Identities = 46/237 (19%), Positives = 86/237 (36%), Gaps = 19/237 (8%)

Query: 37  NTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHD 96
           N+  ++  ++ A+          + TGD+  D S   +  + + +  F+ P + +PGNHD
Sbjct: 60  NSISTFSKLISAVN-EDPVVSFAINTGDMVFDGSVFKWGLYLKQLKRFKVPVLHVPGNHD 118

Query: 97  FQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPE 156
                 + L      P    F       ++L+          +  +QL WLE +L  +  
Sbjct: 119 LADDPGNYL--KIFGPLYYSFHVGNSYFIVLN----NANEKCVDSYQLAWLEGELEKSRS 172

Query: 157 RHTLLLLHHHPLPAG----CSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDW 212
                +  H P+               L+NA  L  +L K+  +  +  GHIH     +W
Sbjct: 173 YKYRFVFMHVPIYDPRVKKQPGHSMKDLKNALTLLNILKKYD-ITMVFAGHIHGYFRGEW 231

Query: 213 NGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELH-ADGTLTTEVHRLADTRFQP 268
           NG   + T             F  +     +  +++H +   +  EV +L    F  
Sbjct: 232 NGVPYIITGGA------GAELFGTNPEHYFYHFIKVHVSPKGVNYEVIKLPTPDFNI 282


>UniRef50_C9NY92 3',5'-cyclic-nucleotide phosphodiesterase n=5 Tax=Vibrionales
           RepID=C9NY92_9VIBR
          Length = 242

 Score =  131 bits (331), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 42/227 (18%), Positives = 86/227 (37%), Gaps = 22/227 (9%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           + QI+D HL  +         ++++ +  L        + D I+ TGD+     S  Y  
Sbjct: 4   VFQISDCHLSDES--------SFQNLEKALNVANA-DSDCDTILLTGDICCGPKSGDYTK 54

Query: 77  FAEGIAS---FRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFG 133
               ++     +     + GNHD    M   L+ + I    +  I  +   + LDS    
Sbjct: 55  LLSFVSQHVDSKKQVYAIAGNHDDIVLMKDELKGSLIQVVDQCEIAGR-HFVFLDSSQKP 113

Query: 134 VPH------GELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELD 187
           +        G +    +  L +++    ++  ++++HH  +  G  W+    L N  ++ 
Sbjct: 114 IDAQHPLGSGRIDNRGIAHLRKQIRK--KKKPIVVVHHPVIRVGSEWMKAICLENDQQIF 171

Query: 188 TVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNF 234
            +L +   V+ ++CGH H  +     G      P+T   F      +
Sbjct: 172 NILKQ-SGVREVICGHGHDHITCTKEGVTQYMAPATAYGFDHSIPEY 217


>UniRef50_UPI000185BF3C putative secreted protein n=1 Tax=Corynebacterium amycolatum SK46
           RepID=UPI000185BF3C
          Length = 485

 Score =  131 bits (330), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 59/294 (20%), Positives = 97/294 (32%), Gaps = 58/294 (19%)

Query: 6   TLP-LAGEARVRILQITDTHLFAQKHEALLGVN------------TWESYQAVLEAIRPH 52
           TLP L+G+    I    DTH+    H+ +   N                 +++L+ ++  
Sbjct: 160 TLPTLSGKLLATIALTNDTHIGKPNHDGIRFGNFGLSSEPGEQPFPSMQLESLLKTVKED 219

Query: 53  QHEFDLIVATGDLAQDQSSAAYQHFAEGIASFR---APCVWLPGNHDFQPAMYSALQDAG 109
             +   IV  GD         Y  F   +  F           GNHD  P     +    
Sbjct: 220 GIDT--IVVNGDCTDSNRPEEYDEFLRVMNQFGEMGKQWFVTRGNHDIHPPGLPNINGRR 277

Query: 110 --------------------ISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLER 149
                                +    V    + +++ LD+  FG   G ++E Q+  +  
Sbjct: 278 GRDIRKGKTYIPDYFSGLLVPTQQHWVTQVGEVRLIGLDTAEFGYAGGRINERQMRAVRA 337

Query: 150 KLADAPERHTLLLLHHHP-------LPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCG 202
           +LA  PER T+L  HH            G S++ +     A  L  +LA  P  K +  G
Sbjct: 338 ELAQDPERPTILFAHHPITDDAVQSHLGGPSFMLER--TQAAALQKILAATPGAKAVFAG 395

Query: 203 HIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTT 256
           H H+       G   +            C   +      G+  + +H DG+  T
Sbjct: 396 HTHRN----RRGVADVGA-------TDFCERGSSLGYPGGYTRIHIHTDGSQVT 438


>UniRef50_A1HNK3 Metallophosphoesterase n=1 Tax=Thermosinus carboxydivorans Nor1
           RepID=A1HNK3_9FIRM
          Length = 345

 Score =  131 bits (330), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 50/196 (25%), Positives = 77/196 (39%), Gaps = 13/196 (6%)

Query: 26  FAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFR 85
           FA   +   G + + S    + A+R      +  V  GDL     +  Y+ F    A   
Sbjct: 126 FAVFGDNRDGRDVYLSLLDKINALR-----PEFAVNGGDLVPAGRAGEYEQFLADSARLT 180

Query: 86  APCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLE 145
            P     GNHD Q    + L +  ++P    F+      L+LD+       G++   QL 
Sbjct: 181 IPYYTALGNHDIQGDGRT-LYNRLLAPNYYDFVWGNSLFLVLDN-----ADGDMDARQLA 234

Query: 146 WLERKLADAPERHTLLLLHHHPL-PAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHI 204
           WLE KL +   RHT +++H  P  P        +S   A  L  + A++  V  + C HI
Sbjct: 235 WLENKLKERTARHTFIIMHKPPFDPRPGRSHTVNSRELADRLQNLAAQY-GVTAVFCSHI 293

Query: 205 HQELDLDWNGRRLLAT 220
           H     +  G     T
Sbjct: 294 HMYYQGERLGVPYYIT 309


>UniRef50_A6WZI2 Metallophosphoesterase n=49 Tax=Proteobacteria RepID=A6WZI2_OCHA4
          Length = 281

 Score =  131 bits (330), Expect = 3e-29,   Method: Composition-based stats.
 Identities = 64/267 (23%), Positives = 99/267 (37%), Gaps = 34/267 (12%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +RI+QITDTHL   K         WE   A ++       + DL++ TGDL  D +    
Sbjct: 1   MRIVQITDTHLSPIKPHFNRN---WEPLVAWIDQ-----QKPDLVIHTGDLTVDGADVEA 52

Query: 75  QHF--AEGIASFRAPCVWLPGNHD-------FQPAMYSALQD--AGISPAKRVFIGEQWQ 123
                   +    A  + LPGNHD        QP     L      I P +       W+
Sbjct: 53  DLLFCRTCLNELPARVLSLPGNHDIGHLPESHQPVNPQRLMRWRRHIGPDRWAENFGNWR 112

Query: 124 ILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQ----HS 179
           I+ L+S V G    E    Q +WLE +L ++  +   +  H           D       
Sbjct: 113 IIGLNSLVIGSGEAE-EAEQFQWLEDELKNSDGKPVAVFAHKPLFVDDPDEGDSGYWGIR 171

Query: 180 LRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTI 239
                 L  + A++ +V+    GH+H+    D  G   +  P+      P   +      
Sbjct: 172 PAPRQRLYDLFAQY-NVQLHASGHLHRAWSGDAFGTNYVWAPAAAFIVGPMERDL----- 225

Query: 240 APGWRTL--ELHA-DGTLTTEVHRLAD 263
            PG R L   +H  D   T+ + R+ +
Sbjct: 226 -PGERILGAAIHDLDEVATSSIVRIDE 251


>UniRef50_B8HPG6 Metallophosphoesterase n=8 Tax=Cyanobacteria RepID=B8HPG6_CYAP4
          Length = 361

 Score =  130 bits (327), Expect = 5e-29,   Method: Composition-based stats.
 Identities = 56/288 (19%), Positives = 103/288 (35%), Gaps = 49/288 (17%)

Query: 16  RILQITDTHL------FAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
           R   ++D H+        QK+   L   +  + + VL+ +     E D ++  GDL Q  
Sbjct: 6   RFGVLSDPHIGLAQTIRDQKNRFHLVEVSIPALEQVLQQMTAA--EVDFLLIPGDLTQHG 63

Query: 70  SSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQ---------------DAGISPAK 114
               +   ++ +A    P   +PGNHD                                 
Sbjct: 64  EPDNHAWLSDRLAQLPFPAYVIPGNHDVPVPFRDGYSIGWSEFPGYYRGYGYGNSDRLYY 123

Query: 115 RVFIGEQWQILLLDSQVFGVPH---GELSEFQLEWLERKLADAPERHTLLLLHHH----- 166
              +    +++ L+S  F       G +   QL WLE  LAD+  +  L+++HH+     
Sbjct: 124 TCELLPGVRLIALNSNQFDHEGVQIGAVDGEQLRWLETVLADSQAKLHLVMIHHNVIEHL 183

Query: 167 PLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQ 226
           P         ++ LR A  L  +L +   VK +  GH+H +   +  G   + T S    
Sbjct: 184 PNQTLHPMGQRYMLRQAETLLQIL-RAGGVKLVFTGHLHVQDIAEAGGIYDITTGS---- 238

Query: 227 FKPHCSNFTLDTIAPGWRTLELHAD--GTLTTEVH--RLADTRFQPDT 270
                    L +    +R +++  +  G +  ++   R+      PD 
Sbjct: 239 ---------LVSYPHPYRIVQIQTEPCGQIQVQIESDRVKSLPDWPDL 277


>UniRef50_C6X3M3 Phosphoribosylglycinamide formyltransferase n=3 Tax=Bacteria
           RepID=C6X3M3_FLAB3
          Length = 425

 Score =  129 bits (325), Expect = 9e-29,   Method: Composition-based stats.
 Identities = 52/254 (20%), Positives = 100/254 (39%), Gaps = 25/254 (9%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           I  ITD HL  +K+ +  GV+   +++ VL+ ++        I+  GDL       A + 
Sbjct: 195 IAFITDLHLH-EKNVSKKGVDAVANWKTVLQDVKAR--GISRIILGGDL---GEKEALKI 248

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDA-GISPAKRVFIGEQWQILLLDSQVFGVP 135
             + I  F      + GNHD      +   +  G               + LD+  +   
Sbjct: 249 IFDDIKDFD--FRLILGNHDKISDFRTFFAETVGKQELYYSAQISGNDCIFLDTSSY--- 303

Query: 136 HGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQ-HSLRNAGELDTVLAKFP 194
             +LS+ Q  +L+  L        ++ +HH  L  G  W+D+ H L+N  +++ +L +  
Sbjct: 304 --KLSQEQRSYLKNWLGSTEN--PVVFIHHPVLDDGS-WMDKEHPLKNKTQVEEILRQSG 358

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTL 254
               L+ GH H    +  +  R + +P+   Q   +  ++  DT + G+  L        
Sbjct: 359 KNVTLISGHYHHFYKVTSDKIRQVISPAVSYQIL-NSKSYQADTKSFGYLIL------GF 411

Query: 255 TTEVHRLADTRFQP 268
           + +   +    F  
Sbjct: 412 SEQEVSIEAVNFSV 425


>UniRef50_Q2JHD6 Ser/Thr protein phosphatase family protein n=12 Tax=Cyanobacteria
           RepID=Q2JHD6_SYNJB
          Length = 386

 Score =  128 bits (323), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 65/292 (22%), Positives = 113/292 (38%), Gaps = 49/292 (16%)

Query: 14  RVRILQITDTH------LFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQ 67
           ++R   ++D H      L+       L   +  + + VL+ +     +   ++  GDL Q
Sbjct: 2   QIRFAVVSDPHVTLPSTLWDHPSRFHLVEVSIPALEQVLQHLVQLPLD--FLLLPGDLTQ 59

Query: 68  DQSSAAYQHFAEGIASFRAPCVWLPGNHDFQ--------------PAMYSALQ-DAGISP 112
                 +   AE +A    P   +PGNHD                P  Y A   + G S 
Sbjct: 60  HGEPENHAWLAERLARLPFPAFVVPGNHDVPQPEASGRSIGLADFPRYYRAFGYEDGQSL 119

Query: 113 AKRVFIGEQWQILLLDSQVFGVPH---GELSEFQLEWLERKLADAPERHTLLLLHHHPLP 169
                +    +++ L+S  F       G L+  QL WLE++LA A E   LL++HH+ + 
Sbjct: 120 DYSRVLRPGIRLIGLNSNHFDAQGQLVGCLTPEQLTWLEKELAAAEEELVLLMVHHNVVE 179

Query: 170 -----AGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTC 224
                +   W  ++ L NA +L  +L  +  V+ +  GH+H +      G   + T S  
Sbjct: 180 HLRGQSLHPWGRRYMLENASQLRRLLQAY-GVQLVFTGHLHIQHIARRGGVYDITTGS-- 236

Query: 225 VQFKPHCSNFTLDTIAPGWRTLELHADGTLTTEVH----RLADTRFQPDTAS 272
                      L +    +R +E+ +D     +VH    R+      PD  +
Sbjct: 237 -----------LVSFPHPYRLVEIRSDRETGIQVHIQSYRVGSLPDWPDLQA 277


>UniRef50_B9C147 Metallophosphoesterase n=1 Tax=Burkholderia multivorans CGD2M
           RepID=B9C147_9BURK
          Length = 404

 Score =  127 bits (320), Expect = 3e-28,   Method: Composition-based stats.
 Identities = 44/224 (19%), Positives = 76/224 (33%), Gaps = 14/224 (6%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
            G  R   LQI+DTH+   K       +   +    +  +        L + TGD+    
Sbjct: 140 PGAGRPLFLQISDTHIGFNKDA---NPDVAATLAQTIALVNAMPETPALAIHTGDITHLS 196

Query: 70  SSAAYQHFAEGIASFRAP-CVWLPGNHDFQP----AMYSALQDAGISPAKRVFIGEQWQI 124
               +   ++ ++  R P    +PG HD         +     A  +     F       
Sbjct: 197 KPDEFDRASQLLSGLRVPELHTVPGEHDVTDGSGAEYFRRFGRASDNRGYYSFDHAGVHF 256

Query: 125 LLLDSQVFGVPH--GELSEFQLEWLERKLADAPERHTLLLLHHHPL-PAGCSWLDQHSLR 181
           + L + +   P+  G   + QL WL + L        +++  H P+      W       
Sbjct: 257 VALVNVMHFKPNGLGSFGDDQLAWLAQDLNGRTSSTPIVVFSHMPMWTIYEPW--GWGTG 314

Query: 182 NAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCV 225
           +A +   +L +F  V  +L GHIHQ +             ST  
Sbjct: 315 DAPQALALLRRFGSVT-VLNGHIHQIVSKVEGNVTFHTARSTAF 357


>UniRef50_UPI0001BC808F hypothetical protein BacD2_17610 n=1 Tax=Bacteroides sp. D2
           RepID=UPI0001BC808F
          Length = 520

 Score =  127 bits (319), Expect = 5e-28,   Method: Composition-based stats.
 Identities = 54/272 (19%), Positives = 103/272 (37%), Gaps = 38/272 (13%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQD----QSSA 72
           I   TD HL   + +  L       Y  ++  I+   ++    +  GD+  D     +  
Sbjct: 115 IFMFTDIHLTNDRVDNDLPQFGKTFYPDIVSQIKARANKPVYAICLGDMTTDVKWHINHY 174

Query: 73  AYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGI----------SPAKRVFIGEQW 122
           A   + E +  F  P     GNHD +  +   + D              P    F    W
Sbjct: 175 ALPEYLETMKDFPIPVYHAMGNHDNERKVIENISDWDFYGESVYKDVIGPNYYSFNIGAW 234

Query: 123 QILLLDSQVFGVP---HG--------ELSEFQLEWLERKLADAPERHTLLLLHHHPLPAG 171
            +++LD+ + G P   +G         + + Q+EW+++ L+  P+   +++  H P P  
Sbjct: 235 HVMILDNIITGGPVKKNGKLNYQFTYRIDDQQMEWIKKDLSFMPKNTPIMVGMHVP-PLK 293

Query: 172 CSWL------DQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDW-NGRRLLATPS-T 223
            + +        +   NA E     A+F  V+ +  GH H+  +  + +   L   PS +
Sbjct: 294 YTGMKNGVLETDYDFENAKEFLDCFAEFNQVQ-IFAGHTHRSSNYVYGDNITLHNLPSAS 352

Query: 224 CVQFKPHCSNFTL---DTIAPGWRTLELHADG 252
            V +K +     L   D    G+  +++  D 
Sbjct: 353 AVSWKINGETSRLISEDGSPAGYWIIKVKGDN 384


>UniRef50_Q2SWK2 Ser/Thr protein phosphatase family protein n=37
           Tax=Burkholderiaceae RepID=Q2SWK2_BURTA
          Length = 306

 Score =  127 bits (319), Expect = 5e-28,   Method: Composition-based stats.
 Identities = 58/247 (23%), Positives = 96/247 (38%), Gaps = 22/247 (8%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA--- 73
            +Q++D H         +  +   +    +EA+       D ++ TGDL       A   
Sbjct: 44  FVQLSDAHWGFSGPA--INPDARGTLPKAIEAVNALPVAPDFVMFTGDLTHTTDDPAERR 101

Query: 74  --YQHFAEGIASFRA-PCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQ 130
              + F   +A  RA P   +PG HD      +A ++         F  +    +++D+ 
Sbjct: 102 TRMRQFQSIVAQLRAKPLHLMPGEHDASLDAGAAYREI-FGDTHYAFDHKGVHFVVVDNV 160

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
               P G + + Q+EWL + LA  P+   +++  H PL       D  + R+  ++  VL
Sbjct: 161 SD--PAGRVGDAQIEWLAQDLARQPKDARIVVFTHRPLFDLAPQWDW-ATRDGAKVVDVL 217

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQF-KPHCSNFTL----DTIAP---- 241
             +P+V  +  GHIHQE           A  S       P   +  L    D  AP    
Sbjct: 218 MPYPNVT-VFYGHIHQEHHAMTGHIAHHAARSLMFPLPAPGSQDKRLPVPWDAAAPYRGL 276

Query: 242 GWRTLEL 248
           GWR + L
Sbjct: 277 GWREVRL 283


>UniRef50_B2TAN8 Metallophosphoesterase n=1 Tax=Burkholderia phytofirmans PsJN
           RepID=B2TAN8_BURPP
          Length = 366

 Score =  126 bits (318), Expect = 6e-28,   Method: Composition-based stats.
 Identities = 55/233 (23%), Positives = 93/233 (39%), Gaps = 27/233 (11%)

Query: 19  QITDTHLFAQKHEALLGVNTWESYQAVLEAIRPH-QHEFDLIVATGDLAQDQSSAAYQHF 77
            I D HL   +    L      + + ++     H   + D  V  GD A D + A Y   
Sbjct: 2   HIGDLHLTEAELPNHL------ALRDIVAQANAHLAGQIDFAVLPGDNADDGTPAQYDIL 55

Query: 78  AEGIASFRAPCVWLPGNHDFQ----PAMYSALQDAGISPAKRVFIGEQWQILLLD--SQV 131
              +     P   +PG+HDF+     A ++ L+   +  A  V     ++   LD  S  
Sbjct: 56  RAELDDLEIPVHIIPGDHDFKSRNLDAFHTVLRAEHLPKATPVR---DYRCFFLDYVSAG 112

Query: 132 FGVPHGELSEFQLEWLERKL--ADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
            G P   L + Q++WL+ +L  A A  + T++  H +P        D      A     +
Sbjct: 113 TGGPDFRLGQSQMDWLKAELQNAAAAGKETVVFAHGYP-------ADLADANEAVAFHRL 165

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPG 242
           L +F  V  +  GH H   +L  +GR + A+  +  Q +   + F+L  +  G
Sbjct: 166 LREF-RVAVVDMGHTHYN-ELANDGRTIYASTRSTGQIEEGPAGFSLLAVDSG 216


>UniRef50_C8ZWM4 Phosphohydrolase n=4 Tax=Enterococcus RepID=C8ZWM4_ENTGA
          Length = 422

 Score =  126 bits (318), Expect = 6e-28,   Method: Composition-based stats.
 Identities = 57/274 (20%), Positives = 105/274 (38%), Gaps = 59/274 (21%)

Query: 9   LAGEARVRILQITDTHL--------------FAQKHEALLGVNTWESYQAVLEAIRPHQH 54
           L  ++      ++D H               FA+           ES +A +      + 
Sbjct: 14  LQQDSESEFWLLSDVHFLSSALHDNSIAFNQFAEGAAGKEMRYQAESLEAFVA--EALEK 71

Query: 55  EFDLIVATGDLAQDQSSAAYQHFAEGIASFR---APCVWLPGNH---------------- 95
               ++ TGD+  +   A+ +  AE +A  +      + LPGNH                
Sbjct: 72  RPTGVILTGDMTLNGEKASAESLAELLAPLQEASIMVLSLPGNHEIYNGWARIFDGDKEF 131

Query: 96  --------DFQPAMYSALQDAG----ISPAKRVFIGEQWQILLLDSQVF--------GVP 135
                   DF+       + A      S +  + + +Q++++LLDS ++           
Sbjct: 132 YADQISPQDFKDIFSEGYEKADSVDRTSLSYSINLNDQYRLVLLDSCIYEEQVNWNQPTT 191

Query: 136 HGELSEFQLEWLERKLADAPERH--TLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKF 193
           +G L E  LEWL+ +L  A ++    LL +HH+ L       + + L N+ +L  +L  +
Sbjct: 192 NGRLKESTLEWLKDQLEAAKQQQQTPLLFMHHNLLEHNSLLKEGYILDNSAQLQQLLTAY 251

Query: 194 PHVKYLLCGHIH-QELDLDWNGRRLLATPSTCVQ 226
             V  +  GHIH Q++    +G + + T S   Q
Sbjct: 252 -QVPAIFSGHIHIQDITEGPSGIQEIVTGSYSTQ 284


>UniRef50_A6DRV9 Ser/Thr protein phosphatase family protein n=1 Tax=Lentisphaera
           araneosa HTCC2155 RepID=A6DRV9_9BACT
          Length = 315

 Score =  126 bits (318), Expect = 7e-28,   Method: Composition-based stats.
 Identities = 47/244 (19%), Positives = 87/244 (35%), Gaps = 28/244 (11%)

Query: 16  RILQITDTHLFAQKHEALLG---------------VNTWESYQAVLEAIRPHQHEFDLIV 60
           R+   +DTH+ A   ++  G               VN  +++     ++         ++
Sbjct: 45  RVALFSDTHISADPKQSYPGTKWPGSPVKDGDHEWVNMADAFTQAANSVIALNPRPAHLI 104

Query: 61  ATGDLA-QDQSSAAYQHFAEGIASFR---APCVWLPGNHDFQPAMY---SALQDAGISPA 113
             GD A  +     Y+     I   R          GNHD +  ++     L+   +   
Sbjct: 105 INGDCALSNGKEGEYKELFRLIEPLRAAGITVHVTIGNHDNREKLWKLLPFLKKQQMGIH 164

Query: 114 KRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCS 173
             V       ++LLDS+        L   QL WL ++L    ++  L+  H++P      
Sbjct: 165 ADVIELPHANLILLDSKTRS-----LGGNQLAWLSQQLDQRADKPALIFSHYNPYA-NRG 218

Query: 174 WLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSN 233
                 LR+   L  +LAK  H +  + GH H+      +   ++  P+    F    +N
Sbjct: 219 VRPIPGLRDGKALLKLLAKRKHARAYINGHTHEWQHDQQDHLHIVNLPAVAYYFGKGHAN 278

Query: 234 FTLD 237
             +D
Sbjct: 279 AWVD 282


>UniRef50_A7C221 Metallophosphoesterase n=1 Tax=Beggiatoa sp. PS RepID=A7C221_9GAMM
          Length = 356

 Score =  126 bits (317), Expect = 9e-28,   Method: Composition-based stats.
 Identities = 46/240 (19%), Positives = 86/240 (35%), Gaps = 31/240 (12%)

Query: 14  RVRILQITDTHLFAQKHEAL-LGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA 72
            +R   I+D H+  +    + +   + E  +  +  I   + E   ++  GDL QD    
Sbjct: 42  SIRFAVISDPHIDIKGKNRVKMSAFSVECLRKTINDIN-QEPELAFVLIVGDLLQDGEWE 100

Query: 73  AYQHFAEGIASFRAPCVWLPGNHDF-------QPAMYS--------ALQDAGISPAKRVF 117
             +     +     P   + GNHDF       +   +              G   + + +
Sbjct: 101 NARVAKNLLDQLLVPYYIICGNHDFMPTFQKQRDGFHYLSVEEFVKFFNGHGFDNSGKRY 160

Query: 118 ----IGEQWQILLLDSQVFGVPH---GELSEFQLEWLERKLADAPERHTLLLLHHHPLP- 169
               I    +++ LD+ +   P    G L E QL WL+++L +      L+ +HH  +  
Sbjct: 161 YAHRIKPGLRLIGLDACLPKEPEKWGGLLPEEQLTWLDKQLTNHANERHLIFIHHSLIRW 220

Query: 170 ----AGCSWLDQHSLRNAGELDTVLAKFPH-VKYLLCGHIHQELD-LDWNGRRLLATPST 223
                         + N  E+  +L+        ++ GH H  L+  + NG      PST
Sbjct: 221 STDELPDGPKQWFCIDNDIEVKNLLSSHAKTAPIVINGHRHTGLNMKEVNGVNYFTMPST 280


>UniRef50_A9APX8 Metallophosphoesterase n=4 Tax=Burkholderia RepID=A9APX8_BURM1
          Length = 312

 Score =  126 bits (316), Expect = 1e-27,   Method: Composition-based stats.
 Identities = 44/224 (19%), Positives = 76/224 (33%), Gaps = 14/224 (6%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
            G  R   LQI+DTH+   K       +   +    +  +        L + TGD+    
Sbjct: 48  PGAGRPLFLQISDTHIGFNKDA---NPDVAATLAQTIALVNAMPETPALAIHTGDITHLS 104

Query: 70  SSAAYQHFAEGIASFRAP-CVWLPGNHDFQP----AMYSALQDAGISPAKRVFIGEQWQI 124
               +   ++ ++  R P    +PG HD         +     A  +     F       
Sbjct: 105 KPDEFDRASQLLSGLRVPELHTVPGEHDVTDGSGAEYFRRFGRASDNRGYYSFDHAGVHF 164

Query: 125 LLLDSQVFGVPH--GELSEFQLEWLERKLADAPERHTLLLLHHHPL-PAGCSWLDQHSLR 181
           + L + +   P+  G   + QL WL + L        +++  H P+      W       
Sbjct: 165 VALVNVMHFKPNGLGSFGDDQLAWLAQDLNGRTSSTPIVVFSHMPMWTIYEPW--GWGTG 222

Query: 182 NAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCV 225
           +A +   +L +F  V  +L GHIHQ +             ST  
Sbjct: 223 DAPQALALLRRFGSVT-VLNGHIHQIVSKVEGNLTFHTARSTAF 265


>UniRef50_Q7NSC8 Putative uncharacterized protein n=1 Tax=Chromobacterium violaceum
           RepID=Q7NSC8_CHRVO
          Length = 318

 Score =  125 bits (315), Expect = 1e-27,   Method: Composition-based stats.
 Identities = 49/230 (21%), Positives = 77/230 (33%), Gaps = 19/230 (8%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
            +QI+DTHL  ++       +   S +  +  I         +V TGD++       +  
Sbjct: 58  FVQISDTHLGFRREA---NPDVQGSLRRAIADINALAKRPAFVVHTGDVSHLSRPEEFDL 114

Query: 77  FAEGIASFRA-PCVWLPGNHDFQP----AMYSALQDAGISPAKRVFIGEQWQILLLDSQV 131
             + +   R      +PG HD                G   A   F       + L++ +
Sbjct: 115 ARQMLKDIRVDRVHTIPGEHDALDDGVSGYLKFFDHDGRHKAWYSFDQGGVHFVALNNVL 174

Query: 132 FGVPH--GELSEFQLEWLERKLADAPERHTLLLLHHHPL---PAGCSWLDQHSLRNAGEL 186
                    L + QL WL+R LA       +++L H PL        W       +A + 
Sbjct: 175 NFSTSRLAALGDEQLAWLKRDLAGLSHSTPVIVLAHIPLWTVYEPWGW----GTADAAQA 230

Query: 187 DTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQF-KPHCSNFT 235
             +L  F  V  +L GHIHQ L        L    S       P  + F 
Sbjct: 231 MALLRPFGSVT-VLNGHIHQVLQKVEGNVALHTARSLAYPLPTPGQAGFG 279


>UniRef50_Q03AS7 Predicted phosphohydrolase n=9 Tax=Lactobacillus RepID=Q03AS7_LACC3
          Length = 442

 Score =  124 bits (313), Expect = 2e-27,   Method: Composition-based stats.
 Identities = 58/298 (19%), Positives = 109/298 (36%), Gaps = 58/298 (19%)

Query: 8   PLAGEARVRILQITDTHLFAQK-----------HEALLGVNTWESYQAVLEAI-RPHQHE 55
           PL   ++  I  ++DTH  A               +  G +      A+   +    +  
Sbjct: 30  PLTNSSQATIWVLSDTHFIAPSLHDEKTAYTQIKRSAAGKDMDYQPVAINALVQNALKAR 89

Query: 56  FDLIVATGDLAQDQSSAAYQHFAEGIASF---RAPCVWLPGNHDF--------------- 97
              +V TGD+  +   A+ +     +          + +PGNHD                
Sbjct: 90  PTALVITGDVTFNGEKASAESIMRRLQPLVANGTKVLIIPGNHDIYDGWARAYKGKRQLL 149

Query: 98  ---------QPAMY----SALQDAGISPAKRVFIGEQWQILLLDSQV--------FGVPH 136
                    +   +     A+     S + RV +   +Q+L+LDS +             
Sbjct: 150 TEQISPSDWRNIFHTSYEQAVAQDPNSLSYRVNLNRNYQLLMLDSNIYTIEPSNRPPNTG 209

Query: 137 GELSEFQLEWLERKLADA--PERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
           G+L+   ++W+ ++LA      R +++ +HH+      +      L N+ +L  +L  + 
Sbjct: 210 GKLTPQTMKWVRQQLAAGQKAHRKSIVFMHHNLYAHNEAVNQGFVLDNSDQLKPLLKAY- 268

Query: 195 HVKYLLCGHIH-QELDLDWNGR-RLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHA 250
           HV  L  GHIH Q++  D +G+   +   S      P    + + T AP   T + HA
Sbjct: 269 HVLLLFSGHIHAQDISRDPDGQCPTIEVVSGAFSISPAS--YGVVTFAPNRITYQKHA 324


>UniRef50_C7PMF7 Metallophosphoesterase n=1 Tax=Chitinophaga pinensis DSM 2588
           RepID=C7PMF7_CHIPD
          Length = 616

 Score =  124 bits (312), Expect = 3e-27,   Method: Composition-based stats.
 Identities = 48/268 (17%), Positives = 89/268 (33%), Gaps = 45/268 (16%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
           A +   R    +DTH+  +           E  +  +  I  +  +   ++ +GD+ +  
Sbjct: 19  AQDTLFRFALASDTHIGNKSG--------AEDLERTVLDIN-NHPDIAFVLFSGDITEFG 69

Query: 70  SSAAYQHFAEGIASFRAPCVWLPGNHDFQ------PAMYSALQDAGISPAKRVFIGEQWQ 123
           S    Q     I+    P   +PGNHD            +       S     F  + + 
Sbjct: 70  SDEEIQLAKSIISKLNKPWYIVPGNHDSNWSESGCNTFLNVFGGETFS-----FRYKGYW 124

Query: 124 ILLLDSQVFG--VPHGELSEFQLEWLERKLADAPERHT-LLLLHHHPLPAGCSWLDQHSL 180
            L   S      +  G++    L WL+ +L    ++   ++ ++H+P           +L
Sbjct: 125 FLGT-SCGPNMRMGPGQVPREDLTWLKEQLRKEKDKKVPVIFVNHYP--------QDSAL 175

Query: 181 RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA 240
            N  E   +L    ++K +LCGH H     D+ G   +   S          N       
Sbjct: 176 NNWYEQLEMLKDR-NLKAILCGHGHANRKYDFEGIPGIMCRS----------NLRAKADT 224

Query: 241 PGWRTLELHADGTLTTEVHRLADTRFQP 268
             +  + L  D  +  E  R+      P
Sbjct: 225 GAYNIISLVHDSLVFNE--RVPGGATLP 250


>UniRef50_UPI00016C4274 hypothetical protein GobsU_18190 n=1 Tax=Gemmata obscuriglobus UQM
           2246 RepID=UPI00016C4274
          Length = 318

 Score =  124 bits (312), Expect = 3e-27,   Method: Composition-based stats.
 Identities = 57/283 (20%), Positives = 97/283 (34%), Gaps = 55/283 (19%)

Query: 12  EARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEA-IRPHQHEFDLIVATGD--LAQD 68
           +  +R   ITD H+   +       +  +   A+          + DLI+ TGD  +A D
Sbjct: 32  KPVLRAAHITDVHITKDR-------DASKGVAAMFAHMANRRDGKPDLILNTGDAVMAVD 84

Query: 69  Q------SSAAYQHFAEGIASFRAPCVWLPGNHDFQPA----------------MYSALQ 106
                  ++     + + + +  AP     GNHD                    M   L 
Sbjct: 85  GKTTGAKAAEQVALWKQAVKAAPAPIHSCLGNHDVWDGNEPTAEVPAEKKGFGLMTEVL- 143

Query: 107 DAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHH 166
             G+      F    W  + L+S      +  LS    +WL+  LA    +   ++L H 
Sbjct: 144 --GMPAPYYSFDKGGWHFVSLNSMCNWPKYATLSPEHFDWLKADLAKT--KLPTVVLSHV 199

Query: 167 PLPAGCSWLDQHSLR--------------NAGELDTVLAKFPHVKYLLCGHIHQELDLDW 212
           P+ +  S +   S R              +   +  V  K PHVK  L GH+H     ++
Sbjct: 200 PILSVTSQVYGDSCRKNNDNVVPGIWHHTDCWAISEVFRKNPHVKLCLSGHMHTCDRCEY 259

Query: 213 NGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLT 255
            G   +   + C  +             P +  ++L ADGT +
Sbjct: 260 RGVWYICGGAACGAWWNGSEY----GFPPCYGAIDLFADGTFS 298


>UniRef50_A6E4I6 Putative uncharacterized protein n=1 Tax=Roseovarius sp. TM1035
           RepID=A6E4I6_9RHOB
          Length = 170

 Score =  122 bits (307), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 36/146 (24%), Positives = 63/146 (43%), Gaps = 6/146 (4%)

Query: 118 IGEQWQILLLDS---QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSW 174
               ++++ LD+       +  G L   +L+WL+++L +A  R  ++  HH P+  G + 
Sbjct: 11  DIGAYRLICLDTLDEAAPDLHSGWLCPARLDWLDQRLNEAGPRPVIVFTHHPPIDTGFAG 70

Query: 175 LDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKP--HCS 232
           +D   LRN  EL   L+   +V  ++ GHIH+ +     G       S C Q        
Sbjct: 71  MDAIGLRNRDELIARLSAADNVVQIMSGHIHRTVQGSAGGIPTAILKSPCHQMPMSLDAQ 130

Query: 233 NFTLDTIAPG-WRTLELHADGTLTTE 257
           + +L    PG +  L L   G +   
Sbjct: 131 DTSLSIDEPGAYGLLLLTETGVIVHT 156


>UniRef50_D1VKL8 Metallophosphoesterase n=1 Tax=Frankia sp. EuI1c RepID=D1VKL8_9ACTO
          Length = 325

 Score =  122 bits (306), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 42/222 (18%), Positives = 81/222 (36%), Gaps = 12/222 (5%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
           A +A +R +Q++D+H+           +   S+   +  +       D ++ TGDL    
Sbjct: 63  ADQATLRFVQVSDSHIGFHGTA---NPDVTGSFARAIAQVNALPDRPDFVMHTGDLTHLS 119

Query: 70  SSAAYQHFAEGIASFRA-PCVWLPGNHDFQP----AMYSALQDAGISPAKRVFIGEQWQI 124
           + A +   ++ +   RA     +PG HD       A  +A            F  +   +
Sbjct: 120 TPAQFDQVSQMMRGLRAGAVHTVPGEHDSVDDGGRAYRAAFGAGSRGDGWYSFDVKGVHV 179

Query: 125 LLLDSQVFGVPHGELSEFQLEWLERKLAD-APERHTLLLLHHHPLPAGCSWLDQHSLRNA 183
           L L + +     G L   QL ++ + +A  + +   L+  H        +W       +A
Sbjct: 180 LALVNTLSLEKLGHLGADQLAFIRQDVAGLSSDTPILVFSHIPLFAMYPTW--GWGTDDA 237

Query: 184 GELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCV 225
            +  + L +F  V   L GH+HQ            +  +T  
Sbjct: 238 VQALSYLRRFSSVT-CLNGHVHQLFSRTEGNVVFRSATTTAY 278


>UniRef50_A0QKV9 Metallophosphoesterase n=4 Tax=Mycobacterium RepID=A0QKV9_MYCA1
          Length = 306

 Score =  122 bits (306), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 38/219 (17%), Positives = 79/219 (36%), Gaps = 10/219 (4%)

Query: 12  EARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
           +  +R  QI+D+HL           +   ++   ++ +    +  D ++ TGDL    + 
Sbjct: 46  QPTLRFAQISDSHLGFTGAP---NPDVAGTFGRAIDQVNNLGYTPDFVIHTGDLTHLSTP 102

Query: 72  AAYQHFAEGIASFRAP-CVWLPGNHDFQP----AMYSALQDAGISPAKRVFIGEQWQILL 126
             +    + +++ + P    +PG HD          S                    ++ 
Sbjct: 103 EQFDQAKQMMSALKTPHVFTVPGEHDSVDDAGQKYRSVFGAGSAGDGWYSLDVAGVHLIA 162

Query: 127 LDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGEL 186
           L + +     G L   QLE++++ +A       +++  H PL A           +A + 
Sbjct: 163 LVNTLNLRKLGHLGADQLEFVKKDVAGLSSDTPIIVFSHIPLFAMYPQW-GWGTDDAAQA 221

Query: 187 DTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCV 225
            + L +F  V   L GH+HQ      +     +  +T  
Sbjct: 222 LSYLRRFASVT-CLNGHVHQLFSKTEDNVTFHSGTTTAY 259


>UniRef50_Q091L6 Ser/Thr protein phosphatase family protein n=1 Tax=Stigmatella
           aurantiaca DW4/3-1 RepID=Q091L6_STIAU
          Length = 343

 Score =  121 bits (303), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 52/246 (21%), Positives = 92/246 (37%), Gaps = 39/246 (15%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
             + +     I+DTHL+ QK           S    ++ +     + D ++  GDLAQ  
Sbjct: 34  PEKPKFTFAYISDTHLYEQKLNDRF----VRSILKAVDDVNALDPQPDFVLFGGDLAQLG 89

Query: 70  SSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDS 129
            +   +  A+ + S +AP   + G HD+   M    ++    P    F  +    ++L+S
Sbjct: 90  QAGELKLGAQILKSVKAPVRMMVGEHDWFLDMGELWRELFGEPT-YSFDHKGIHFVVLNS 148

Query: 130 -------------------QVFGVPHG-----ELSEFQLEWLERKLADAPERHTLLLLHH 165
                               V G+ +G     E+   Q  WL++ LA   ++  +++  H
Sbjct: 149 IQEKDFWTERGLTPMQRMQIVAGLDNGIQSRFEVGAEQRAWLQKDLAKVDKKTPVIVFSH 208

Query: 166 HPL----PAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATP 221
            PL         W D     +A E+  +L  F  V  ++ GH HQ L    +        
Sbjct: 209 SPLYKYYKPWNFWTD-----DADEVQALLKPFEKVT-VIHGHTHQLLTNRIDNIHFHGML 262

Query: 222 STCVQF 227
           ST   +
Sbjct: 263 STAWPW 268


>UniRef50_A3ZYM0 Putative uncharacterized protein n=1 Tax=Blastopirellula marina DSM
           3645 RepID=A3ZYM0_9PLAN
          Length = 291

 Score =  121 bits (303), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 51/291 (17%), Positives = 101/291 (34%), Gaps = 51/291 (17%)

Query: 4   LLTLPLAGEA--RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVA 61
           + +L  A EA    R   +TD H+  +       ++  E ++  L ++   +   ++IV 
Sbjct: 1   MPSLARAEEAAQPFRFAHLTDIHVQPE-------LSAGEGFRKCLASVNALEKRPEVIVT 53

Query: 62  TGDLAQDQSSAAYQHFAEGIA--------SFRAPCVWLPGNHDFQPAMYS---------- 103
            GD+  D  +   Q   +  +            P     GNHD     +           
Sbjct: 54  GGDMVMDIFAHNRQRADQLFSLYGDVVKGETDIPFRSCIGNHDVFGWSHRQDVKPEDAEF 113

Query: 104 ----ALQDAGISPAKRVFIGEQWQILLLDSQVFGVPH---GELSEFQLEWLERKLADAPE 156
                 +  G+      F    W+  +LD       +     L E Q EWL++ L + P 
Sbjct: 114 GKGLVCEKLGLEKTYYAFDQGGWRFYILDDIQMAPNNRYQAYLEEEQFEWLKKDLEEKPA 173

Query: 157 RHTLLLLHHHPLPAGCSWLD------------QHSLRNAGELDTVLAKFPHVKYLLCGHI 204
               +++ H P+    ++ +                R A +L  + +K  +VK  L GH 
Sbjct: 174 ETPAVVVSHIPIYTVSTFDNGREEDLAYRVGFSAMCREAAKLGNLFSKH-NVKLALSGHH 232

Query: 205 HQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLT 255
           H    +++ G   +   +    +           +  G+  ++L+ +GT  
Sbjct: 233 HILERIEFQGVTYICGGAVSGGWWRGPHR----GVQEGFGLVDLNPNGTFD 279


>UniRef50_C6XUF6 Metallophosphoesterase n=1 Tax=Pedobacter heparinus DSM 2366
           RepID=C6XUF6_PEDHD
          Length = 611

 Score =  120 bits (301), Expect = 5e-26,   Method: Composition-based stats.
 Identities = 45/243 (18%), Positives = 90/243 (37%), Gaps = 34/243 (13%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           +   +TDTH+     E           +  +  I     + D IV TGD+ +  +    +
Sbjct: 23  KYAFVTDTHVGTATGEED--------LRRTVNDINKQT-DLDFIVVTGDVTEMGTKLELK 73

Query: 76  HFAEGIASFRAPCVWLPGNHD---FQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVF 132
                ++  + P   +PGNHD    +      +++ G    K  F    ++ +   S  +
Sbjct: 74  LAKSILSELKKPYYVIPGNHDTGWSESGGVDFIREFGDD--KFTFDHNGYRFIACASGPY 131

Query: 133 GV-PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
                G +    + WL++ L +      ++ ++H+P+         +SL N  E    + 
Sbjct: 132 VRMSDGHIPRDAVIWLDKVLKNTSATMPVIFINHYPV--------DNSLDNWYEATDRIK 183

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHAD 251
           K+ +++Y +CGH H    L++ G       S          N        G+  + +  D
Sbjct: 184 KY-NIQYAICGHGHSNQALNFEGVPGTMGRS----------NLRAKDSLGGYNIVTMRKD 232

Query: 252 GTL 254
             L
Sbjct: 233 SVL 235


>UniRef50_B3C782 Putative uncharacterized protein n=2 Tax=Bacteroides
           RepID=B3C782_9BACE
          Length = 618

 Score =  119 bits (300), Expect = 9e-26,   Method: Composition-based stats.
 Identities = 40/251 (15%), Positives = 91/251 (36%), Gaps = 34/251 (13%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
              ++D HL +  +         +  +  +E I  +  + D  + +GD+ +   +  +  
Sbjct: 20  FAWLSDVHLNSFAYAE-------DDLRQSIEDINAN-PDVDFTILSGDVTEFGDTKEFYL 71

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYS-ALQDAGISPAKRVFIGEQWQILLLD---SQVF 132
             + +  FR P   +PGNHD   +     + D     +   +  +  + +      S   
Sbjct: 72  LQDILKDFRKPYFLIPGNHDVNWSENGCTMFDKIFQASHFCYDWQGVRFIGCGAGPSLRM 131

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
           G PH  +   ++ WL+  +   P +  ++ ++H PL           L N  E+  +L  
Sbjct: 132 GPPH--IPREEILWLDSIVRATPAKQPIIFINHFPL--------NQDLSNWYEVIDILK- 180

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADG 252
             +++ +L GH+H     D  G   +   S          +   +    G+  + L  + 
Sbjct: 181 TRNIQAVLGGHLHVNHAYDAEGIPAVIGRS----------SLRREDTIGGYNLVHLRGNT 230

Query: 253 -TLTTEVHRLA 262
                 + ++ 
Sbjct: 231 LEFNERIIKVE 241


>UniRef50_A3WFW5 Putative uncharacterized protein n=1 Tax=Erythrobacter sp. NAP1
           RepID=A3WFW5_9SPHN
          Length = 248

 Score =  119 bits (299), Expect = 9e-26,   Method: Composition-based stats.
 Identities = 60/266 (22%), Positives = 93/266 (34%), Gaps = 38/266 (14%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           R+  ++D H          GV   E+ + V +AIR  + +   +V TGD+ Q    + Y 
Sbjct: 4   RLFHVSDVHF---------GVENREALEHVAKAIRDERPD--ALVCTGDVTQRAKHSEYA 52

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV----------FIGEQWQIL 125
             AE  A    P V  PGNHD     Y  L +    P +R           F  +   ++
Sbjct: 53  AAAEWFAGLGVPVVLEPGNHDMP---YYNLLERFSDPYRRFRRLDSEVGSRFENDDVVLV 109

Query: 126 LLDSQVFGVP-----HGELSEFQLEWLERKLADAPE--RHTLLLLHHHPLPAGCSWLDQH 178
            L S V   P      G +++  LE    +L       RH ++  HH  L       D  
Sbjct: 110 SLKSTVRAQPRFPWSDGIVTKRSLERTLAELRKLSGDPRHVIVTAHHPLL---GPKEDAG 166

Query: 179 SLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDT 238
           +    G+             ++ GH+H+  D        +A  S  +      S      
Sbjct: 167 NPTIGGDRAFAALASAGADAIMTGHVHRPFDETRE----MAGASMRMIGAGTLSTRLRHG 222

Query: 239 IAPGWRTLELHADGTLTTEVHRLADT 264
             P +R L       +  E+  LA T
Sbjct: 223 APPSYRVLNCRRGEEMQVELRELAAT 248


>UniRef50_C5SJD5 Metallophosphoesterase n=1 Tax=Asticcacaulis excentricus CB 48
           RepID=C5SJD5_9CAUL
          Length = 257

 Score =  119 bits (299), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 58/267 (21%), Positives = 95/267 (35%), Gaps = 36/267 (13%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +RI  I+D H  A            E+  + L  +     E DL+VA+GD+ QD + A +
Sbjct: 1   MRIAHISDLHFGAHDRR------VTETLISTLIEL-----EPDLVVASGDITQDATVAEF 49

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV-------FIGEQWQILLL 127
              +E       P   +PGNHD                   +          +   I  +
Sbjct: 50  VEASEFFKLLPMPAFVIPGNHDLPGLDLRRFIQPWKRYRDHIARELEPELQADLVDIKGI 109

Query: 128 DSQVFGVP-----HGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRN 182
           +S    +P     +G +S  Q   +    A +     +L +HH PL      LD  +L N
Sbjct: 110 NSARMILPSLNWAYGSISARQRHDIADFFAASTTPWRVLTVHHPPLNPPEFPLD-VTLFN 168

Query: 183 AGELDTVLAKFPHVKYLLCGHIHQELDLDW---NGRRLLATPSTCVQFKPHCSNFTLDTI 239
            G+    L +   V  +L GH H              L    ST +  +       +   
Sbjct: 169 KGKFLETLGE-QKVDIVLSGHQHHAYVETRIMNGHTTLFVCASTAMSVR-------IRKQ 220

Query: 240 APGWRTLELHADGTLTTEVHRLADTRF 266
             G+  L+   D ++  E+ +L+  RF
Sbjct: 221 PQGFNLLDFK-DKSVRIELRQLSGDRF 246


>UniRef50_D0LMB8 Metallophosphoesterase n=1 Tax=Haliangium ochraceum DSM 14365
           RepID=D0LMB8_HALO1
          Length = 374

 Score =  118 bits (297), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 51/262 (19%), Positives = 91/262 (34%), Gaps = 42/262 (16%)

Query: 11  GEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQS 70
           G+   R   I+D+HL+ +            +    +E I     + D +   GDLAQ   
Sbjct: 66  GDGGFRFAYISDSHLYPETKNDRF----VRALMRAVEDINRLDPQPDFVFYGGDLAQLGR 121

Query: 71  SAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDS- 129
                  A+ +   +AP   + G HD+   M    +     P +  +  +   +++L+S 
Sbjct: 122 PDELGLGAQILKEVKAPLKMMVGEHDWYYDMGETWRGLFGEP-RYSWDHKGVHLVVLNSV 180

Query: 130 ------------------QVFGVPHGE-----LSEFQLEWLERKLADAPERHTLLLLHHH 166
                              V G+ +G      + + Q+ WL+  LA       +++  H 
Sbjct: 181 IEEDFWTARGLTPEQRMQTVAGLDNGAQNPFTVGDEQIAWLKNDLAQVDRNTPIIVFSHS 240

Query: 167 PLPAGCS----WLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPS 222
           PL         W D     +A ++  VL  F  V  ++ GH HQ L             S
Sbjct: 241 PLYKLYKKWNFWTD-----DAEKVQAVLQPFRKVT-VIHGHTHQILTNRIGNIHFHGMLS 294

Query: 223 TCVQF---KPHCSNFTLDTIAP 241
           T   +         +T++   P
Sbjct: 295 TAWPWPYAPEGMPEYTVEMSRP 316


>UniRef50_C6J7N6 Metallophosphoesterase n=2 Tax=Bacillales RepID=C6J7N6_9BACL
          Length = 233

 Score =  118 bits (297), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 49/210 (23%), Positives = 75/210 (35%), Gaps = 19/210 (9%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           R   ITDTH+ A +           + +  L+ I  +      I+  GD+        Y+
Sbjct: 20  RFRVITDTHVRADEQHTH-----NVNLERALQDIAANGTGSVGIMHAGDVTDHGFPDEYE 74

Query: 76  HFAEGIASFR---APCVWLPGNHDFQPAMYSA-----LQDAGISPAKRVFIGEQWQILLL 127
            +      F     P     GNHD     + A     L+  G          + +  + L
Sbjct: 75  AWNRNWHRFGGAVPPLYVTMGNHDVALENWEARLGQFLRGTGAEGIYHDHWIDGYHFIFL 134

Query: 128 DSQVFGVPHGELSEFQLEWLERKLAD--APERHTLLLLHHHPLPAGCSWLDQ---HSLRN 182
            ++        LSE QL WL+ KL +  A +R   + LH   L       +    + +  
Sbjct: 135 GTEEGLELFSSLSEKQLAWLDDKLGENAAADRPVFVFLHQPLLNTVAGSYEAQRWYGVVQ 194

Query: 183 AGELDTVLAKFPHVKYLLCGHIHQELDLDW 212
             +L  VLA+ P    L  GH H ELD   
Sbjct: 195 DADLRAVLARHPQ-AILFTGHTHWELDASH 223


>UniRef50_A0RA77 Purple acid phosphatase/fibronectin domain protein n=79
           Tax=Bacillus RepID=A0RA77_BACAH
          Length = 824

 Score =  118 bits (296), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 49/248 (19%), Positives = 98/248 (39%), Gaps = 24/248 (9%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
             E ++    ++D H+     +     +T+  ++  +E +     + D  V  GD     
Sbjct: 48  PSEKKIVFPVVSDVHIKNSGTD-----DTF-RWKRAIEQLNTLAPKQDAFVIVGDFTDTG 101

Query: 70  SSAAYQHFAEGI---ASFRAPCVWLPGNHDF------QPAMYSALQDAGISPAKRVFIGE 120
           S   Y  F +     A+  A  +   GNHD+      + A    L+  G+       + +
Sbjct: 102 SLQQYDRFMQVYNENANKDAVRMNSLGNHDYWNGLSVEGAQKRFLEKTGMESIYYHKVVK 161

Query: 121 QWQILLLDSQVFGVPHGELSEFQLEWLERKLADA----PERHTLLLLHHHPLPAGCSWLD 176
            +  L++ S   G  HG  S+ Q+ WL+ ++A A    PE+   + LH H +        
Sbjct: 162 GYHFLVM-SPENGTTHGYYSDKQINWLKEEMAKAQKDDPEKPIFVFLHQH-IKETVYGSH 219

Query: 177 QHSLRNAGELDTVLAKFPHVKYLLCGHIHQELD--LDWNGRRLLATPSTCVQFKPHCSNF 234
           +   +++ +++TVL ++P       GH H  LD     + +   +  ++ + +       
Sbjct: 220 EWGTQDSAKINTVLKEYPQAIT-FSGHSHYPLDDPRSIHQKDFTSVGTSSISYMEVEGGK 278

Query: 235 TLDTIAPG 242
               I PG
Sbjct: 279 VQGNIPPG 286


>UniRef50_B6YTV2 Metallophosphoesterase n=2 Tax=Thermococcus RepID=B6YTV2_THEON
          Length = 545

 Score =  118 bits (295), Expect = 3e-25,   Method: Composition-based stats.
 Identities = 37/237 (15%), Positives = 87/237 (36%), Gaps = 13/237 (5%)

Query: 29  KHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPC 88
            H +  G    E +  ++E I  ++ +   I+ +GDL    +   +    +    +  P 
Sbjct: 320 DHRSDGGTEVPEVFLKIMEEINNNEEDAVFIIDSGDLIYSGTVDQWAALLDEW-EWEKPI 378

Query: 89  VWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLE 148
              PGNH+++    +        P    F+   +  + +++         LS+ Q  WL+
Sbjct: 379 FIAPGNHEYRGEGINIYHML-FGPTDYSFVLGDYYYIFMNNIENDYS---LSDEQWVWLQ 434

Query: 149 RKLADAPE--RHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQ 206
            +L  A E  +  ++++H  P+          +  +   L  ++ ++ +   +  GHIH 
Sbjct: 435 DELEKAEEMGKRPVIVMHAPPVDPRPEGDHGMNPTDGKRLLQLMKEY-NAFGIF-GHIHM 492

Query: 207 ELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTEVHRLAD 263
               + +G   +   +              D     +  L +  DG++  E  ++  
Sbjct: 493 FWYGEKDGAEFVVAGAAGAPLYASPDEGGFDH----YTRLFMATDGSIGVEPVKVEP 545


>UniRef50_B6IMU0 3',5'-cyclic-nucleotide phosphodiesterase, putative n=1
           Tax=Rhodospirillum centenum SW RepID=B6IMU0_RHOCS
          Length = 286

 Score =  118 bits (295), Expect = 3e-25,   Method: Composition-based stats.
 Identities = 52/249 (20%), Positives = 91/249 (36%), Gaps = 29/249 (11%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPH--QHEFDLIVATGDLAQDQSSAA 73
           RI  I+D H           ++      AV+ A+R        DLIV +GDL Q    + 
Sbjct: 3   RIAHISDLHFG--------RIDP-----AVVAALRDDLAAQAPDLIVVSGDLTQRARPSQ 49

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQP-AMYSALQDAGISPAKRV-------FIGEQWQIL 125
           ++     +A   AP + +PGNHD     + + L D   +  + +              +L
Sbjct: 50  FRAARAFLADLPAPHMVVPGNHDLPAFNLLARLVDPLRNYRRYIAEDLDPFLNLGNLAVL 109

Query: 126 LLDSQ---VFGVPHGELSEFQLEWLERKLAD-APERHTLLLLHHHPLPAGCSWLDQHSLR 181
            L++    +     G +++ Q++ +   L +  PE   ++  HH  LP       +   R
Sbjct: 110 GLNTSRSLILDFAEGRVNQRQMDRILGCLRELGPEVFKVVFTHHPFLPPPDHPGRRLVGR 169

Query: 182 NAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAP 241
               L  +  +   V  LL GH+H+    D          S  V      ++  L     
Sbjct: 170 ATRALRAL--EAAGVDLLLAGHLHRAYSGDVMSHHAHVERSILVAQASTATSTRLRNEPN 227

Query: 242 GWRTLELHA 250
            W  +E+  
Sbjct: 228 AWNLIEIAP 236


>UniRef50_B1ZFT6 Metallophosphoesterase n=1 Tax=Methylobacterium populi BJ001
           RepID=B1ZFT6_METPB
          Length = 387

 Score =  117 bits (294), Expect = 4e-25,   Method: Composition-based stats.
 Identities = 54/248 (21%), Positives = 78/248 (31%), Gaps = 24/248 (9%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
           A +  +    I D HL   +                L A        D +   GD A + 
Sbjct: 3   ARDDLLVFAHIGDLHLTDPQAGNARDY-------RALIAQLDEADGLDFVFLPGDNADNG 55

Query: 70  SSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSAL-QDAGISPAKRVFIGEQWQILLLD 128
               Y     G+   R P   + G+HD +     A     G+            + L LD
Sbjct: 56  RPEQYALVRAGLDGLRLPAHVITGDHDMEGGSLDAFYAGLGVPRLPYAVTVSGTRCLFLD 115

Query: 129 --SQVFGVPHGELSEFQLEWLERKL--ADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAG 184
                 G P   L   QL WLER+L  A+A  R   L +H +P                 
Sbjct: 116 LCGSGSGGPDFRLGSEQLSWLERELAGAEAEGRDCALFMHSYPADLKAEG-------EGT 168

Query: 185 ELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNF---TLDTIAP 241
            +  ++ + P V+ +  GH H     +       A  ST  Q +     +    LD    
Sbjct: 169 RVAELVHRGP-VRLVEMGHTHYNELANDGRTVYAACRST-GQIEEGPVGYAIAALDRGGV 226

Query: 242 GWRTLELH 249
            WR  EL 
Sbjct: 227 AWRFKELD 234


>UniRef50_Q6LRK7 Putative uncharacterized protein n=2 Tax=Photobacterium profundum
           RepID=Q6LRK7_PHOPR
          Length = 247

 Score =  117 bits (293), Expect = 5e-25,   Method: Composition-based stats.
 Identities = 54/258 (20%), Positives = 103/258 (39%), Gaps = 31/258 (12%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +RI Q++D HL     EA        +    L+ I  +  +  +++ TGDL  + S   Y
Sbjct: 1   MRIYQVSDCHLQTGNTEA------SANLVRALQHIEGNG-DGAILLLTGDLVCNPSVDVY 53

Query: 75  QHFAEGIASFRA--PCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQV- 131
           +HF E I +  +      + GNHD    M +  + + I   K V +    +++ +DS   
Sbjct: 54  EHFREIIETHVSISEIYAIAGNHDDFEMMKAVFKSSRIMVKKTVKLAIGCRLIFVDSSQK 113

Query: 132 ----FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELD 187
                 +  G +S   L  L++    + +  +++++HH  +  G  W  Q  + N   + 
Sbjct: 114 PLTNMPLGSGRVSNKDLSLLKKW---SRKTPSIVVVHHPVVDVGTEWFTQIGIENKAAVV 170

Query: 188 TVLAKFPHVKYLLCGHIHQELDL-DWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTL 246
             +        ++ GH H    +    G   +  P+TC  F         D   P +  +
Sbjct: 171 RAIHHHT--LSVISGHAHSFFKVPVKEGISQVVCPATCYGF---------DHANPCYERI 219

Query: 247 ELHADGTLTTEVHRLADT 264
           E    G +   + R+ +T
Sbjct: 220 E--EIGIMYYGIERVGET 235


>UniRef50_B2IDE3 Metallophosphoesterase n=34 Tax=Bacteria RepID=B2IDE3_BEII9
          Length = 335

 Score =  117 bits (293), Expect = 5e-25,   Method: Composition-based stats.
 Identities = 43/221 (19%), Positives = 73/221 (33%), Gaps = 18/221 (8%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
            +QI+D+H+   K       N   + +  ++ I+   H+   ++ TGD+        +  
Sbjct: 73  FIQISDSHIGFDKPA---NPNALATLREAIDQIKALPHKPAFMIHTGDITHLSKDKEFDD 129

Query: 77  FAEGIASFRAPCVWLPGNHD--FQPAMYSALQDAGISP-------AKRVFIGEQWQILLL 127
             + +     P   +PG HD        + L   G  P           F  +    + L
Sbjct: 130 ADQILKEAGLPIFTVPGEHDLLDDSQGKAYLDRYGRGPLVKALGAGWYSFDQKGIHYIAL 189

Query: 128 DSQVFGVPH--GELSEFQLEWLERKLADAPERHTLLLLHHHPL-PAGCSWLDQHSLRNAG 184
            +         G L   QL WL   +A       +++  H PL      W       +  
Sbjct: 190 VNVTDLKAGGLGNLGAEQLAWLAADVALLSSSTPIVVFAHIPLWTVYAEW--GWGTEDGA 247

Query: 185 ELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCV 225
           +    L +F  V  +L GHIHQ +             ST  
Sbjct: 248 KALETLKRFGSVT-VLNGHIHQIMQKVEGHVAFHTARSTAF 287


>UniRef50_A6EBB1 Putative uncharacterized protein n=2 Tax=Sphingobacteriales
           RepID=A6EBB1_9SPHI
          Length = 306

 Score =  116 bits (291), Expect = 8e-25,   Method: Composition-based stats.
 Identities = 53/265 (20%), Positives = 93/265 (35%), Gaps = 37/265 (13%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA---- 72
           +  ITD H+         G    E +++ L  I  ++H+ D  +  GD   D S      
Sbjct: 45  VAHITDVHIRE-------GDRAAERFRSCLNHI-INKHKPDFFLNGGDAINDASYDNVVR 96

Query: 73  -----AYQHFAEGIASF-RAPCVWLPGNHDF-------QPAMY---SALQDAGISPAKRV 116
                 +  + + + +          GNHD           MY     ++   +      
Sbjct: 97  EQVISQWAIWDDCLTTLKGYEVHSCIGNHDTWWKAPTTSDPMYGKDYVVKRLKMPHRYYS 156

Query: 117 FIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLD 176
           F  + W   +LD     +    L E Q  WLE +L        +LL+ H+P+      L 
Sbjct: 157 FSRKNWHFFILDGNNANIS---LDEEQYNWLEAELGKLRAGSQVLLMSHYPILGTTQVLV 213

Query: 177 QHSLRNAGELDTVLAKF-PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCS--- 232
                +  +L  +  K+   V+  L GH H   + ++NG R     +    +        
Sbjct: 214 GGGHSDCKKLKDLFYKYRDKVRICLSGHNHLSDETEYNGVRYCCNGAMSGFWWGKGDAES 273

Query: 233 --NFTLDTIAPGWRTLELHADGTLT 255
             +       PG+  L+L+ DGT+ 
Sbjct: 274 KGDGYYLETPPGYAILDLYDDGTVE 298


>UniRef50_C4WQD0 Putative uncharacterized protein n=1 Tax=Ochrobactrum intermedium
           LMG 3301 RepID=C4WQD0_9RHIZ
          Length = 294

 Score =  115 bits (289), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 52/278 (18%), Positives = 90/278 (32%), Gaps = 40/278 (14%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ--SSAAY 74
           ILQI+DTHL  +               A        + + D IV TGD+  D       Y
Sbjct: 17  ILQISDTHLSPRTDHFRENNRLLAEPLA--------ESDHDFIVHTGDVTLDGIRYDEDY 68

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQP----------------AMYSALQDAGISPAKRVFI 118
               +          +L GNHD                   A   A         + V  
Sbjct: 69  ALCRDFFKESGKTIHFLAGNHDVGDNPNLSKPESENGSAINAARYARFADYFGADRWVID 128

Query: 119 GEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQH 178
             +W+I+ + S + G    +    Q +W+++++  + +R+  +  H          +D  
Sbjct: 129 QGKWRIIGISSMLIGSGLPQ-EAEQYDWIDQQITSSGDRYLAVFSHQP---IYIDNMDST 184

Query: 179 SL-------RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHC 231
            L       +  G L+ ++   P ++ +  GH+HQ+         L    S         
Sbjct: 185 ELTYWTVDPKGWGRLEGLIN-HPKLRLIASGHLHQQRSSKRGNVHLEWCSSIAFTTTEEL 243

Query: 232 SNFTLDTIAPGWRTLELHADGTLTTEVHRLADTRFQPD 269
                 T   G+       DG + ++V  L    F  D
Sbjct: 244 VPEMGGTREVGYMEHHFSDDGRVESKV--LKHDGFAND 279


>UniRef50_Q2NGW0 Predicted phosphohydrolase n=2 Tax=Methanobacteriaceae
           RepID=Q2NGW0_METST
          Length = 243

 Score =  115 bits (289), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 54/257 (21%), Positives = 98/257 (38%), Gaps = 38/257 (14%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           +I+ I+D H               +     ++ I   Q     +V +GDL        + 
Sbjct: 3   KIVHISDLH-------TGYAQFREDLLLQTIDEINKIQP--SAVVISGDLTDQGFYREFI 53

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIG--EQWQILLLDSQVFG 133
              E I   +   + +PGNHD +    +  ++        V     E  +I+ LDS    
Sbjct: 54  EAKEYIDLIQPKTLIVPGNHDARNIGDTVFEEL-FGKRYSVLELKEEAIKIIGLDSSEPD 112

Query: 134 VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPL----------PAGCSWLDQHSLRNA 183
           + HG++   Q +++E ++ADA E+                         +  +++ L +A
Sbjct: 113 LGHGKIGRLQKKFMEDEIADAKEKG--------LFIIIVLHHHIISIPNTGRERNILSDA 164

Query: 184 GE-LDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFK---PHCSNFTLDTI 239
           G+ L T+L    +V  +L GH H       N   L AT  T    K     C ++ +  I
Sbjct: 165 GDILLTILE--NNVNLVLSGHKHVPHAWKMNN-TLFATAGTVSSMKLRGNTCPSYNVIDI 221

Query: 240 APGWRTLELH-ADGTLT 255
              +  + LH ++GT+ 
Sbjct: 222 NNQYIEIMLHNSNGTIK 238


>UniRef50_A9B0W4 Metallophosphoesterase n=1 Tax=Herpetosiphon aurantiacus ATCC 23779
           RepID=A9B0W4_HERA2
          Length = 288

 Score =  115 bits (288), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 50/206 (24%), Positives = 86/206 (41%), Gaps = 24/206 (11%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA-YQ 75
           IL ++D H     +         E  Q +LEA    Q +  L V +GD  Q     + + 
Sbjct: 5   ILHLSDLHAGPPFNP--------EKAQQILEA--AWQIKPTLTVLSGDFVQRADIRSQWL 54

Query: 76  HFAEGIASFRAPCVWLPGNHDFQ--PAMYSALQDAGISPAK------RVFIGEQWQILLL 127
              + +A    P + + GNHD     A+Y  L+               V+  + +  + +
Sbjct: 55  TIRDFVAQLPQPTIAVMGNHDVPLYNALYRMLRPNYYYKKYISPILEPVWGNDDFVAVGV 114

Query: 128 DSQ-VFGVPHGELSEFQLEWLERKLADAPERH-TLLLLHHHPLPAGCSWLDQHSLRNAGE 185
           ++   F V  G+L++ QL  LER LA  P+    ++++HHHP+       D    +NA  
Sbjct: 115 NTTRSFTVDGGKLTDQQLLELERSLARYPDSLCKIVVMHHHPVMPPGETRDVI--QNAAA 172

Query: 186 LDTVLAKFPHVKYLLCGHIHQELDLD 211
                 +  +V+ +LCGH H     +
Sbjct: 173 ALRTFDR-SNVELVLCGHTHASYIGN 197


>UniRef50_Q03NU9 Predicted phosphohydrolase n=1 Tax=Lactobacillus brevis ATCC 367
           RepID=Q03NU9_LACBA
          Length = 288

 Score =  115 bits (288), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 48/201 (23%), Positives = 74/201 (36%), Gaps = 11/201 (5%)

Query: 11  GEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQS 70
           G  R  I+ I+D  L    ++ L      +  Q + + +  HQ   DLIV +GDL     
Sbjct: 5   GMNRFTIVHISDIDLTMDDNQRL----ATQPLQRIFDDLEDHQVAADLIVLSGDLLIGGD 60

Query: 71  SAAYQHFAEGIA----SFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQ-IL 125
              Y+   + +       +     L G+ D + A           P        Q     
Sbjct: 61  QQGYRQLHQYLQQQERRLQVTIQVLLGDRDDREAFNRGYLAVAHQPYYADKQVHQNMDFY 120

Query: 126 LLDSQ-VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAG 184
            LDS+       G L   QL+WL + L  AP R   + LHH         +    L+N  
Sbjct: 121 FLDSKWELNKSAGWLDRPQLDWLNKNLHLAPRRRAFIFLHHPLDAPALRDMRYTLLQNNR 180

Query: 185 ELDTVLAKFPHVKYLLCGHIH 205
           EL  +L    ++  +  GH+H
Sbjct: 181 ELLAILHGH-NIGGIFTGHLH 200


>UniRef50_B9K5P3 Putative uncharacterized protein n=1 Tax=Agrobacterium vitis S4
           RepID=B9K5P3_AGRVS
          Length = 278

 Score =  114 bits (287), Expect = 3e-24,   Method: Composition-based stats.
 Identities = 56/270 (20%), Positives = 107/270 (39%), Gaps = 38/270 (14%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS--A 72
           ++I  + D H+ +Q    +      E+++AV++ +  ++ + +L +  GDL  D ++  A
Sbjct: 1   MKIAILADPHIGSQNDVFV------ENWKAVVKTVNGYE-DVELAIVLGDLTLDGANIEA 53

Query: 73  AYQHFAEGIASFRAPCVWLPGNHDF-----------QPAMYSALQDAGISPAKRVFIGEQ 121
                A  + +  AP + LPGNHD              A  +A +    +   +    E 
Sbjct: 54  DLAFGAAQLKAINAPVLVLPGNHDIGDIARDSTQPADDARLAAWETHFGAWYWQCDAVEG 113

Query: 122 WQILLLDSQVFGVPHGELSEFQLEW--LERKLADAPERHTLLLLHHHPLPAGCSWLDQHS 179
           W+++ L+SQ+ G     L   + +W  LE  L +  +R  +L LH        +  D+ +
Sbjct: 114 WRLIGLNSQIIGSG---LPAEEQQWSALENMLKERGDRKPVLFLHMPLFLEDWNEGDRPA 170

Query: 180 L----RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLA-TPSTCVQFKPHCSNF 234
                     L  ++ +   V  ++ GH+H+ L L      +L  TP++    +      
Sbjct: 171 WALKTEGRLRLQRLIMEH-GVFAVVSGHMHRTLHLQQKNEPVLIWTPASSFLARDESM-- 227

Query: 235 TLDTIAPGWRTL--ELHADGTLTTEVHRLA 262
                 PG   L   L   G     V  + 
Sbjct: 228 ---PSQPGKELLGVTLLDFGKDDISVEFID 254


>UniRef50_C7PXI9 Metallophosphoesterase n=2 Tax=Actinomycetales RepID=C7PXI9_CATAD
          Length = 314

 Score =  113 bits (284), Expect = 5e-24,   Method: Composition-based stats.
 Identities = 36/216 (16%), Positives = 78/216 (36%), Gaps = 10/216 (4%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +R +Q++D+H+           +   S+   ++ +       + ++ TGDL    ++A +
Sbjct: 57  LRFVQVSDSHIGFTGPA---NTDVTASFTEAIDQVNSLGFRPNFVMHTGDLTHLSTAAQF 113

Query: 75  QHFAEGIASFRA-PCVWLPGNHDFQ----PAMYSALQDAGISPAKRVFIGEQWQILLLDS 129
               + ++  R      +PG HD       A                F       + L +
Sbjct: 114 DQVKQMLSEVRTERVFTVPGEHDSVGDSGRAYRQTFGAGTTGDGWYSFDTHGVHFIALVN 173

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
            +     G L   Q++++ + +A       +++  H PL A        S  ++ ++  +
Sbjct: 174 TLSLEKLGHLGNDQIDFVRKDVAGLSSDTPIVVFSHIPLFAMYPAW-GWSTDDSLQVLAL 232

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCV 225
           L +F  V   L GH+HQ            +  +T  
Sbjct: 233 LRRFASVT-CLNGHVHQLFSKTEGNVTFHSATTTAY 267


>UniRef50_C5AJE8 Metallophosphoesterase n=1 Tax=Burkholderia glumae BGR1
           RepID=C5AJE8_BURGB
          Length = 370

 Score =  113 bits (284), Expect = 5e-24,   Method: Composition-based stats.
 Identities = 54/248 (21%), Positives = 93/248 (37%), Gaps = 31/248 (12%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRP-HQHEFDLIVATGDLAQDQSSAA 73
           +R +   D H  +       G  + +  ++++  +        D     GD A + +   
Sbjct: 2   LRWVHFGDLHASSDD-----GYESLDHLRSMIRLVNQGLSDRVDFAFLPGDNANNGTPEQ 56

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGIS--PAKRVFIGEQWQILLLDSQV 131
           ++  +  +++ R P   +PG+HD++P    A      +  PA RV  G +   L L S  
Sbjct: 57  FRRISAELSALRLPIYVIPGDHDYEPGNLDAFNAFAQARLPASRVLNGHRCIFLDLVSAG 116

Query: 132 FGVPHGELSEFQLEWLERKLADAPER--HTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
            G P   LS    +WLER+LA   +      + +H +P   G          +   L   
Sbjct: 117 RGGPDFRLSAPDRQWLERELACCAQDREPPAVFMHAYPGDVG----------DGPALAEA 166

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELH 249
            A+   V  +  GH H    L+       AT ST  Q +        D   PG+    + 
Sbjct: 167 FAR-AKVAVVDTGHTHYNELLNDGFVIYAATRST-GQIEE-------DGGRPGFSVAAV- 216

Query: 250 ADGTLTTE 257
            DG + + 
Sbjct: 217 -DGGVVSW 223


Searching..................................................done


Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_P0AEW5 Protein icc n=161 Tax=Gammaproteobacteria RepID=...   311   2e-83
UniRef50_C4L9C4 Calcineurin phosphoesterase domain protein n=3 T...   282   1e-74
UniRef50_P44685 Protein icc homolog n=27 Tax=Pasteurellaceae Rep...   282   1e-74
UniRef50_B8HUH6 Metallophosphoesterase n=2 Tax=Chroococcales Rep...   277   4e-73
UniRef50_Q1N2L2 Metallophosphoesterase n=1 Tax=Bermanella marisr...   275   1e-72
UniRef50_Q4KJ96 Cyclic AMP phosphodiesterase n=25 Tax=Bacteria R...   275   2e-72
UniRef50_Q0VLK4 Icc protein, putative n=2 Tax=Alcanivorax RepID=...   274   2e-72
UniRef50_B0C4F0 3',5'-cyclic-nucleotide phosphodiesterase n=1 Ta...   274   3e-72
UniRef50_A1SZX9 Cyclic AMP phosphodiesterase n=2 Tax=Psychromona...   270   3e-71
UniRef50_Q2S9N2 Predicted phosphohydrolase n=1 Tax=Hahella cheju...   270   4e-71
UniRef50_A1TYT4 Calcineurin phosphoesterase C-terminal domain pr...   267   3e-70
UniRef50_Q8YLG0 3',5'-cyclic-nucleotide phosphodiesterase n=3 Ta...   265   9e-70
UniRef50_A4BSE9 Ser/Thr protein phosphatase n=1 Tax=Nitrococcus ...   264   2e-69
UniRef50_C6AKV1 Icc n=6 Tax=Pasteurellaceae RepID=C6AKV1_AGGAN        264   3e-69
UniRef50_UPI0001698C6A Calcineurin phosphoesterase C-terminal do...   263   6e-69
UniRef50_A4B8Z0 Putative uncharacterized protein n=1 Tax=Reineke...   262   1e-68
UniRef50_A0YY40 3',5'-cyclic-nucleotide phosphodiesterase n=1 Ta...   260   3e-68
UniRef50_C7R6J1 Metallophosphoesterase n=1 Tax=Kangiella koreens...   257   4e-67
UniRef50_D2U2B8 Cyclic 3',5'-adenosine monophosphate phosphodies...   255   9e-67
UniRef50_B8GLR4 Icc protein n=1 Tax=Thioalkalivibrio sp. HL-EbGR...   255   1e-66
UniRef50_B7S0L2 Calcineurin-like phosphoesterase C-terminal doma...   253   6e-66
UniRef50_A6F721 Icc protein-like protein n=1 Tax=Moritella sp. P...   252   7e-66
UniRef50_A4A8X3 Icc protein n=2 Tax=unclassified Gammaproteobact...   252   9e-66
UniRef50_C5SEA9 Calcineurin phosphoesterase domain protein n=1 T...   251   2e-65
UniRef50_Q7MNX9 Cyclic AMP phosphodiesterase n=60 Tax=Gammaprote...   251   2e-65
UniRef50_Q12J78 Metallophosphoesterase n=21 Tax=Shewanella RepID...   247   3e-64
UniRef50_A3M1D0 Cyclic 3'5'-adenosine monophosphate phosphodiest...   247   3e-64
UniRef50_B5JTJ8 Metallophosphoesterase n=1 Tax=gamma proteobacte...   245   1e-63
UniRef50_A0Y9K0 Cyclic AMP phosphodiesterase n=1 Tax=marine gamm...   245   2e-63
UniRef50_Q606D3 Cyclic AMP phosphodiesterase n=1 Tax=Methylococc...   244   2e-63
UniRef50_Q21NU3 Metallophosphoesterase n=3 Tax=Gammaproteobacter...   242   7e-63
UniRef50_Q3JEM1 Metallophosphoesterase n=2 Tax=Nitrosococcus oce...   237   3e-61
UniRef50_Q2JPZ0 Icc protein n=2 Tax=Synechococcus RepID=Q2JPZ0_S...   233   6e-60
UniRef50_Q2KTW6 cAMP phosphodiesterase n=5 Tax=Bordetella RepID=...   232   7e-60
UniRef50_Q2KTP2 Putative phosphohydrolase n=1 Tax=Bordetella avi...   231   2e-59
UniRef50_A0Z341 Metallophosphoesterase n=1 Tax=marine gamma prot...   231   2e-59
UniRef50_B9ZKN4 Calcineurin phosphoesterase domain protein n=1 T...   229   1e-58
UniRef50_B1XQ99 Putative 3',5'-cyclic-nucleotide phosphodiestera...   228   1e-58
UniRef50_B8KUM1 Cyclic AMP phosphodiesterase n=1 Tax=gamma prote...   228   2e-58
UniRef50_B1KBF2 Metallophosphoesterase n=5 Tax=Proteobacteria Re...   227   4e-58
UniRef50_Q1YUP4 CAMP phosphodiesterase n=1 Tax=gamma proteobacte...   223   5e-57
UniRef50_Q0EZ19 Ser/Thr protein phosphatase n=1 Tax=Mariprofundu...   222   1e-56
UniRef50_Q3JU10 Ser/Thr protein phosphatase family protein n=72 ...   221   2e-56
UniRef50_B6R8M8 Ser/Thr protein phosphatase family protein n=1 T...   218   1e-55
UniRef50_B3Q6B8 Metallophosphoesterase n=8 Tax=Bradyrhizobiaceae...   218   2e-55
UniRef50_Q0AC05 Metallophosphoesterase n=1 Tax=Alkalilimnicola e...   217   4e-55
UniRef50_C8PWU2 Calcineurin phosphoesterase domain protein n=1 T...   216   8e-55
UniRef50_C6CXY6 Metallophosphoesterase n=1 Tax=Paenibacillus sp....   215   1e-54
UniRef50_Q1QUF7 Metallophosphoesterase n=1 Tax=Chromohalobacter ...   215   1e-54
UniRef50_Q1MS94 Phosphodiesterase n=1 Tax=Lawsonia intracellular...   214   3e-54
UniRef50_D1A354 Metallophosphoesterase n=1 Tax=Thermomonospora c...   214   3e-54
UniRef50_Q1LDS0 Metallophosphoesterase n=10 Tax=Proteobacteria R...   213   4e-54
UniRef50_Q1Q887 Metallophosphoesterase n=2 Tax=Psychrobacter Rep...   213   5e-54
UniRef50_C1CX57 Putative Metallophosphoesterase; putative cAMP p...   213   5e-54
UniRef50_A1ZTZ2 Metallophosphoesterase n=1 Tax=Microscilla marin...   212   1e-53
UniRef50_A7IH99 Metallophosphoesterase n=2 Tax=Xanthobacteraceae...   211   2e-53
UniRef50_A6D2K7 Ser/Thr protein phosphatase family protein n=1 T...   211   2e-53
UniRef50_A3RQT5 Icc protein n=4 Tax=Ralstonia solanacearum RepID...   210   3e-53
UniRef50_Q2BR54 Metallophosphoesterase n=1 Tax=Neptuniibacter ca...   210   4e-53
UniRef50_Q4ZTD8 Metallophosphoesterase n=4 Tax=Pseudomonas syrin...   210   4e-53
UniRef50_B0UF90 Metallophosphoesterase n=2 Tax=Methylobacterium ...   210   4e-53
UniRef50_A8U260 Ser/Thr protein phosphatase family protein n=1 T...   209   1e-52
UniRef50_D1U8L8 Metallophosphoesterase n=1 Tax=Desulfovibrio aes...   209   1e-52
UniRef50_Q89MQ1 Bll4141 protein n=1 Tax=Bradyrhizobium japonicum...   208   2e-52
UniRef50_A8ZM80 Phosphodiesterase, putative n=1 Tax=Acaryochlori...   207   2e-52
UniRef50_B9QUB7 Ser/Thr protein phosphatase family protein n=1 T...   207   2e-52
UniRef50_A0NY27 Metallophosphoesterase n=2 Tax=Rhodobacteraceae ...   205   1e-51
UniRef50_Q2J948 Metallophosphoesterase n=5 Tax=Actinomycetales R...   203   5e-51
UniRef50_B8J1S2 Metallophosphoesterase n=1 Tax=Desulfovibrio des...   203   6e-51
UniRef50_Q162P5 Ser/Thr protein phosphatase family protein, puta...   202   9e-51
UniRef50_A4EV76 3',5'-cyclic-nucleotide phosphodiesterase, cpdA ...   202   1e-50
UniRef50_C6D6T3 Metallophosphoesterase n=1 Tax=Paenibacillus sp....   201   2e-50
UniRef50_Q1GM28 Metallophosphoesterase n=3 Tax=Rhodobacteraceae ...   201   3e-50
UniRef50_C6DHP5 Metallophosphoesterase n=5 Tax=Proteobacteria Re...   200   5e-50
UniRef50_B1A0M0 Ser/Thr protein phosphatase family protein n=3 T...   200   6e-50
UniRef50_C8SU16 Metallophosphoesterase n=1 Tax=Mesorhizobium opp...   200   6e-50
UniRef50_A7BW21 Cyclic AMP phosphodiesterase n=1 Tax=Beggiatoa s...   199   9e-50
UniRef50_A4F6Q6 Cyclic nucleotide phosphodiesterase n=7 Tax=Acti...   198   1e-49
UniRef50_C6A0T0 Predicted phosphohydrolase n=6 Tax=Thermococcus ...   198   1e-49
UniRef50_C1AX97 3',5'-cyclic-nucleotide phosphodiesterase n=24 T...   198   2e-49
UniRef50_A0NQD3 Ser/Thr protein phosphatase family protein n=1 T...   197   3e-49
UniRef50_Q982B7 Mll9148 protein n=1 Tax=Mesorhizobium loti RepID...   197   4e-49
UniRef50_A5FX65 Metallophosphoesterase n=1 Tax=Acidiphilium cryp...   197   4e-49
UniRef50_B5J8T8 Ser/Thr protein phosphatase family protein n=2 T...   197   4e-49
UniRef50_A5WBU9 Calcineurin phosphoesterase C-terminal domain pr...   197   4e-49
UniRef50_D2U008 3',5'-cyclic-nucleotide phosphodiesterase n=1 Ta...   196   5e-49
UniRef50_C6BIA6 Metallophosphoesterase n=2 Tax=Ralstonia pickett...   196   6e-49
UniRef50_C5T0E1 Metallophosphoesterase n=1 Tax=Acidovorax delafi...   196   6e-49
UniRef50_B6WYD4 Putative uncharacterized protein n=1 Tax=Desulfo...   195   1e-48
UniRef50_B0P519 Putative uncharacterized protein n=2 Tax=Clostri...   195   1e-48
UniRef50_A9FYQ8 Phosphodiesterase n=6 Tax=Rhodobacteraceae RepID...   195   1e-48
UniRef50_Q7NZT6 3',5'-cyclic-nucleotide phosphodiesterase n=1 Ta...   195   2e-48
UniRef50_B3TB35 Putative calcineurin-like phosphoesterase n=1 Ta...   194   2e-48
UniRef50_Q0FF25 Putative uncharacterized protein n=1 Tax=Rhodoba...   194   3e-48
UniRef50_P05675 Uncharacterized protein syc0937_d n=2 Tax=Synech...   193   4e-48
UniRef50_B7QYI4 3',5'-cyclic-nucleotide phosphodiesterase, CpdA ...   193   4e-48
UniRef50_A4C954 Cyclic 3',5'-adenosine monophosphate phosphodies...   193   5e-48
UniRef50_A3WHQ7 Putative cAMP phosphodiesterase n=1 Tax=Erythrob...   191   1e-47
UniRef50_C7S9W5 Protein icc n=17 Tax=Bacteria RepID=C7S9W5_ECOLX      191   2e-47
UniRef50_A4EJU5 3',5'-cyclic-nucleotide phosphodiesterase, cpdA ...   191   2e-47
UniRef50_B6J9P9 3',5'-cyclic-nucleotide phosphodiesterase n=7 Ta...   191   2e-47
UniRef50_D1XS68 Metallophosphoesterase n=1 Tax=Streptomyces sp. ...   191   3e-47
UniRef50_A2C6L9 Serine/threonine specific protein phosphatase n=...   191   3e-47
UniRef50_C6WAT1 Metallophosphoesterase n=1 Tax=Actinosynnema mir...   190   3e-47
UniRef50_B5JAZ3 Ser/Thr protein phosphatase family protein n=2 T...   190   4e-47
UniRef50_B6IT97 Phosphodiesterase, putative n=1 Tax=Rhodospirill...   189   8e-47
UniRef50_Q3AIR5 Possible ICC (3',5'-cyclic-nucleotide phosphodie...   188   2e-46
UniRef50_Q5Z214 Putative phosphodiesterase n=1 Tax=Nocardia farc...   188   2e-46
UniRef50_A9CKB5 Putative uncharacterized protein n=2 Tax=Alphapr...   187   3e-46
UniRef50_Q8TVF8 Predicted calcineurin superfamily phosphohydrola...   187   3e-46
UniRef50_A4AIJ2 Putative uncharacterized protein n=1 Tax=marine ...   187   3e-46
UniRef50_A6U5M4 Metallophosphoesterase n=3 Tax=Rhizobiaceae RepI...   187   4e-46
UniRef50_UPI0001B53F99 metallophosphoesterase n=1 Tax=Streptomyc...   186   5e-46
UniRef50_B3Q702 Metallophosphoesterase n=5 Tax=Alphaproteobacter...   186   7e-46
UniRef50_Q4JN56 Predicted 3',5'-cyclic-nucleotide phosphodiester...   186   7e-46
UniRef50_C0WNK1 3',5'-cyclic-nucleotide phosphodiesterase n=3 Ta...   185   1e-45
UniRef50_Q1GWA3 Metallophosphoesterase n=1 Tax=Sphingopyxis alas...   185   1e-45
UniRef50_C9RR52 Metallophosphoesterase n=1 Tax=Fibrobacter succi...   185   2e-45
UniRef50_C9CTH4 Phosphodiesterase n=6 Tax=Proteobacteria RepID=C...   184   3e-45
UniRef50_B7BFD3 Putative uncharacterized protein n=1 Tax=Parabac...   184   3e-45
UniRef50_Q2J3S6 Metallophosphoesterase n=5 Tax=Rhodopseudomonas ...   183   6e-45
UniRef50_C7D8R5 Phosphodiesterase n=1 Tax=Thalassiobium sp. R2A6...   183   6e-45
UniRef50_A3W656 Ser/Thr protein phosphatase family protein n=3 T...   183   7e-45
UniRef50_A5CN72 Putative 3',5'-cyclic-nucleotide phosphodiestera...   183   8e-45
UniRef50_A9DF72 Possible 3',5'-cyclic-nucleotide phosphodiestera...   183   8e-45
UniRef50_C9AD97 Phosphoesterase n=3 Tax=Enterococcus casseliflav...   182   9e-45
UniRef50_Q2RNL1 Metallophosphoesterase n=1 Tax=Rhodospirillum ru...   182   1e-44
UniRef50_Q47WJ3 Cyclic AMP phosphodiesterase n=1 Tax=Colwellia p...   181   1e-44
UniRef50_A5UK60 Predicted phosphohydrolase, calcineurin-like sup...   181   3e-44
UniRef50_C5CDX7 Metallophosphoesterase n=1 Tax=Kosmotoga olearia...   181   3e-44
UniRef50_C6VLV6 3',5'-cyclic-nucleotide phosphodiesterase n=3 Ta...   180   4e-44
UniRef50_A5GLK1 Predicted phosphohydrolase n=4 Tax=Synechococcus...   179   7e-44
UniRef50_C8XD18 Metallophosphoesterase n=1 Tax=Nakamurella multi...   179   7e-44
UniRef50_A5V3T9 Metallophosphoesterase n=2 Tax=Sphingomonadaceae...   179   9e-44
UniRef50_B5K790 Metallophosphoesterase n=1 Tax=Octadecabacter an...   178   2e-43
UniRef50_B5JMC7 Ser/Thr protein phosphatase family protein n=1 T...   178   2e-43
UniRef50_Q28NL1 Metallophosphoesterase n=2 Tax=Rhodobacteraceae ...   178   2e-43
UniRef50_Q9V2G8 Predicted phosphohydrolase, putative n=3 Tax=Pyr...   178   2e-43
UniRef50_A3JT02 Putative uncharacterized protein n=1 Tax=Rhodoba...   178   2e-43
UniRef50_D2AYX4 Metallophosphoesterase n=10 Tax=Actinomycetales ...   177   3e-43
UniRef50_D2QL03 Metallophosphoesterase n=1 Tax=Spirosoma lingual...   177   4e-43
UniRef50_Q20ZN1 Metallophosphoesterase n=1 Tax=Rhodopseudomonas ...   176   5e-43
UniRef50_A3K5W8 Phosphodiesterase n=1 Tax=Sagittula stellata E-3...   176   6e-43
UniRef50_B4RZD1 3,5-cyclic-nucleotide phosphodiesterase n=2 Tax=...   176   7e-43
UniRef50_Q1AXD2 Metallophosphoesterase n=1 Tax=Rubrobacter xylan...   176   8e-43
UniRef50_C8S8V3 Metallophosphoesterase n=1 Tax=Ferroglobus placi...   175   1e-42
UniRef50_D0L6V7 Metallophosphoesterase n=1 Tax=Gordonia bronchia...   175   2e-42
UniRef50_Q15YS5 Metallophosphoesterase n=1 Tax=Pseudoalteromonas...   174   3e-42
UniRef50_D2PMS5 Metallophosphoesterase n=1 Tax=Kribbella flavida...   174   3e-42
UniRef50_A1AWV4 Metallophosphoesterase n=5 Tax=Bacteria RepID=A1...   173   4e-42
UniRef50_D2QP98 Metallophosphoesterase n=1 Tax=Spirosoma lingual...   173   5e-42
UniRef50_A9CI50 Putative uncharacterized protein n=1 Tax=Agrobac...   173   5e-42
UniRef50_C7D3F7 Predicted protein n=5 Tax=Enterococcus RepID=C7D...   173   6e-42
UniRef50_C7PKP5 Metallophosphoesterase n=1 Tax=Chitinophaga pine...   173   8e-42
UniRef50_O66909 Putative uncharacterized protein n=1 Tax=Aquifex...   171   2e-41
UniRef50_Q1AVF9 Metallophosphoesterase n=1 Tax=Rubrobacter xylan...   171   2e-41
UniRef50_Q7NJG1 Glr1871 protein n=1 Tax=Gloeobacter violaceus Re...   170   3e-41
UniRef50_A9DXP9 Putative uncharacterized protein n=1 Tax=Oceanib...   170   4e-41
UniRef50_A3U194 Putative uncharacterized protein n=1 Tax=Oceanic...   170   7e-41
UniRef50_O30241 LacZ expression regulatory protein (Icc) n=1 Tax...   168   1e-40
UniRef50_B5YAA1 Membrane-associated protein, putative n=2 Tax=Di...   165   1e-39
UniRef50_A9A2N5 Metallophosphoesterase n=4 Tax=marine archaeal g...   165   1e-39
UniRef50_C7MAF7 Predicted phosphohydrolase n=1 Tax=Brachybacteri...   164   3e-39
UniRef50_A6W423 Metallophosphoesterase n=1 Tax=Kineococcus radio...   164   3e-39
UniRef50_Q091L6 Ser/Thr protein phosphatase family protein n=1 T...   164   3e-39
UniRef50_A1SEE2 Metallophosphoesterase n=2 Tax=Actinobacteria (c...   163   7e-39
UniRef50_O27755 Transcriptional regulator Icc related protein n=...   161   2e-38
UniRef50_B1LAV7 Metallophosphoesterase n=2 Tax=Thermotoga sp. RQ...   161   2e-38
UniRef50_B9TNQ0 Putative uncharacterized protein (Fragment) n=1 ...   160   4e-38
UniRef50_D0LMB8 Metallophosphoesterase n=1 Tax=Haliangium ochrac...   160   4e-38
UniRef50_A0QKV9 Metallophosphoesterase n=4 Tax=Mycobacterium Rep...   160   5e-38
UniRef50_Q5UEX4 Predicted Ser/Thr protein phosphatase family pro...   159   6e-38
UniRef50_Q64Z92 Serine/threonine protein kinase related protein ...   159   7e-38
UniRef50_A9WNR5 Putative 3',5'-cyclic-nucleotide phosphodiestera...   159   7e-38
UniRef50_D2QD99 Metallophosphoesterase n=1 Tax=Spirosoma lingual...   159   8e-38
UniRef50_C5EL28 Predicted protein n=1 Tax=Clostridiales bacteriu...   159   9e-38
UniRef50_Q7NSC8 Putative uncharacterized protein n=1 Tax=Chromob...   159   9e-38
UniRef50_Q0RKV8 Putative uncharacterized protein n=1 Tax=Frankia...   159   9e-38
UniRef50_Q2JP63 Ser/Thr protein phosphatase family protein n=2 T...   159   1e-37
UniRef50_D2EUB1 Metallophosphoesterase n=1 Tax=Bacteroides sp. D...   159   1e-37
UniRef50_D2PQZ3 Metallophosphoesterase n=1 Tax=Kribbella flavida...   159   1e-37
UniRef50_A5FYX3 Metallophosphoesterase n=1 Tax=Acidiphilium cryp...   158   2e-37
UniRef50_B8HPG6 Metallophosphoesterase n=8 Tax=Cyanobacteria Rep...   158   2e-37
UniRef50_D1N465 Metallophosphoesterase n=1 Tax=Victivallis vaden...   158   2e-37
UniRef50_B9C147 Metallophosphoesterase n=1 Tax=Burkholderia mult...   158   2e-37
UniRef50_C2FYP3 Metallophosphoesterase n=1 Tax=Sphingobacterium ...   157   3e-37
UniRef50_UPI00016C4274 hypothetical protein GobsU_18190 n=1 Tax=...   157   5e-37
UniRef50_B2IDE3 Metallophosphoesterase n=34 Tax=Bacteria RepID=B...   156   5e-37
UniRef50_A3ZYM0 Putative uncharacterized protein n=1 Tax=Blastop...   156   7e-37
UniRef50_Q2JHD6 Ser/Thr protein phosphatase family protein n=12 ...   156   8e-37
UniRef50_B9K806 Metallophosphoesterase n=1 Tax=Thermotoga neapol...   156   1e-36
UniRef50_A9APX8 Metallophosphoesterase n=4 Tax=Burkholderia RepI...   156   1e-36
UniRef50_Q6ACA7 Putative uncharacterized protein n=1 Tax=Leifson...   155   2e-36
UniRef50_C5PKR3 Putative uncharacterized protein n=2 Tax=Sphingo...   154   2e-36
UniRef50_C6VU97 Metallophosphoesterase n=1 Tax=Dyadobacter ferme...   154   2e-36
UniRef50_B6YTV2 Metallophosphoesterase n=2 Tax=Thermococcus RepI...   154   3e-36
UniRef50_B3C782 Putative uncharacterized protein n=2 Tax=Bactero...   153   5e-36
UniRef50_C8QH10 Metallophosphoesterase n=3 Tax=Enterobacteriacea...   153   5e-36
UniRef50_C1VB71 Predicted phosphohydrolase n=1 Tax=Halogeometric...   153   6e-36
UniRef50_C7PMF7 Metallophosphoesterase n=1 Tax=Chitinophaga pine...   153   9e-36
UniRef50_D1VKL8 Metallophosphoesterase n=1 Tax=Frankia sp. EuI1c...   152   9e-36
UniRef50_C7PXI9 Metallophosphoesterase n=2 Tax=Actinomycetales R...   151   2e-35
UniRef50_Q46D43 3,5-cyclic-nucleotide phosphodiesterase n=8 Tax=...   151   3e-35
UniRef50_C7NWB5 Metallophosphoesterase n=1 Tax=Halomicrobium muk...   151   3e-35
UniRef50_A6CD50 Cyclic 3',5'-adenosine monophosphate phosphodies...   151   3e-35
UniRef50_B4D428 Metallophosphoesterase n=1 Tax=Chthoniobacter fl...   151   3e-35
UniRef50_UPI0000588F73 PREDICTED: hypothetical protein n=2 Tax=S...   149   8e-35
UniRef50_C8WD30 Metallophosphoesterase n=5 Tax=Alphaproteobacter...   149   1e-34
UniRef50_D0TER0 Metallophosphoesterase n=2 Tax=Bacteroidales Rep...   149   1e-34
UniRef50_A7C221 Metallophosphoesterase n=1 Tax=Beggiatoa sp. PS ...   149   1e-34
UniRef50_UPI0001744C1C hypothetical protein VspiD_21990 n=1 Tax=...   148   2e-34
UniRef50_A1ZMS0 Putative uncharacterized protein n=1 Tax=Microsc...   148   2e-34
UniRef50_A7HEA8 Metallophosphoesterase n=1 Tax=Anaeromyxobacter ...   148   2e-34
UniRef50_B6IMU0 3',5'-cyclic-nucleotide phosphodiesterase, putat...   147   4e-34
UniRef50_A4A1K6 Ser/Thr protein phosphatase family protein (Frag...   147   4e-34
UniRef50_C6B6U2 Metallophosphoesterase n=2 Tax=Rhizobium legumin...   146   5e-34
UniRef50_B7QLZ2 Purple acid phosphatase, putative n=2 Tax=Coelom...   146   6e-34
UniRef50_C5SJD5 Metallophosphoesterase n=1 Tax=Asticcacaulis exc...   146   6e-34
UniRef50_A6EBB1 Putative uncharacterized protein n=2 Tax=Sphingo...   146   6e-34
UniRef50_Q2SWK2 Ser/Thr protein phosphatase family protein n=37 ...   146   6e-34
UniRef50_UPI0001745388 Ser/Thr protein phosphatase family protei...   146   8e-34
UniRef50_Q9YDE7 Putative uncharacterized protein n=1 Tax=Aeropyr...   146   1e-33
UniRef50_D2EY57 Putative uncharacterized protein n=1 Tax=Bactero...   146   1e-33
UniRef50_A6WZI2 Metallophosphoesterase n=49 Tax=Proteobacteria R...   146   1e-33
UniRef50_B9TAV3 Putative uncharacterized protein n=1 Tax=Ricinus...   145   1e-33
UniRef50_C6XUF6 Metallophosphoesterase n=1 Tax=Pedobacter hepari...   144   2e-33
UniRef50_Q3Y3L7 Metallophosphoesterase n=1 Tax=Enterococcus faec...   144   2e-33
UniRef50_C6A3A3 Metallophosphoesterase, calcineurin superfamily ...   144   2e-33
UniRef50_UPI00019737CF serine/threonine protein phosphatase fami...   144   3e-33
UniRef50_A4WK20 Metallophosphoesterase n=5 Tax=Thermoproteaceae ...   144   3e-33
UniRef50_UPI0001BC808F hypothetical protein BacD2_17610 n=1 Tax=...   143   7e-33
UniRef50_A6WWL5 Metallophosphoesterase n=1 Tax=Ochrobactrum anth...   143   7e-33
UniRef50_A1HNK3 Metallophosphoesterase n=1 Tax=Thermosinus carbo...   143   8e-33
UniRef50_B4WC05 Ser/Thr protein phosphatase family protein n=1 T...   143   9e-33
UniRef50_A6DB66 Putative uncharacterized protein n=1 Tax=Caminib...   143   9e-33
UniRef50_C1ZIM9 Predicted phosphohydrolase n=1 Tax=Planctomyces ...   143   9e-33
UniRef50_C6X3M3 Phosphoribosylglycinamide formyltransferase n=3 ...   143   9e-33
UniRef50_B9XC60 Metallophosphoesterase n=1 Tax=bacterium Ellin51...   142   1e-32
UniRef50_C5EF84 Serine/threonine protein phosphatase family prot...   141   2e-32
UniRef50_D1B7Z2 Metallophosphoesterase n=1 Tax=Thermanaerovibrio...   141   2e-32
UniRef50_C7PSE2 Putative uncharacterized protein n=1 Tax=Chitino...   141   2e-32
UniRef50_Q2NGW0 Predicted phosphohydrolase n=2 Tax=Methanobacter...   141   2e-32
UniRef50_UPI000186DB0B conserved hypothetical protein n=1 Tax=Pe...   141   2e-32
UniRef50_B0T252 Metallophosphoesterase n=5 Tax=Caulobacteraceae ...   141   3e-32
UniRef50_B7R2D1 Metallophosphoesterase, calcineurin superfamily ...   141   3e-32
UniRef50_C5U614 Metallophosphoesterase n=1 Tax=Methanocaldococcu...   141   3e-32
UniRef50_A8URX6 Putative uncharacterized protein n=1 Tax=Hydroge...   141   3e-32
UniRef50_B3QLB7 Metallophosphoesterase n=2 Tax=Chlorobaculum Rep...   140   4e-32
UniRef50_UPI000185BF3C putative secreted protein n=1 Tax=Coryneb...   140   5e-32
UniRef50_A1ZDF2 Probable beta-galactosidase, putative n=1 Tax=Mi...   140   5e-32

Sequences not found previously or not previously below threshold:

>UniRef50_P0AEW5 Protein icc n=161 Tax=Gammaproteobacteria RepID=ICC_ECO57
          Length = 275

 Score =  311 bits (797), Expect = 2e-83,   Method: Composition-based stats.
 Identities = 275/275 (100%), Positives = 275/275 (100%)

Query: 1   MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV 60
           MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
Sbjct: 1   MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV 60

Query: 61  ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE 120
           ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
Sbjct: 61  ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE 120

Query: 121 QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL 180
           QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
Sbjct: 121 QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL 180

Query: 181 RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA 240
           RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
Sbjct: 181 RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA 240

Query: 241 PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY 275
           PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
Sbjct: 241 PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY 275


>UniRef50_C4L9C4 Calcineurin phosphoesterase domain protein n=3
           Tax=Gammaproteobacteria RepID=C4L9C4_TOLAT
          Length = 273

 Score =  282 bits (721), Expect = 1e-74,   Method: Composition-based stats.
 Identities = 137/271 (50%), Positives = 185/271 (68%), Gaps = 1/271 (0%)

Query: 5   LTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGD 64
            TL    +  VR+LQI+DTHLFA+ +  LLG+ T +S+QAVL+AI      +D+++ATGD
Sbjct: 4   CTLSKPDDGIVRLLQISDTHLFAETNRDLLGIATADSFQAVLDAITELPQTYDVVLATGD 63

Query: 65  LAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQI 124
           L+QD S+A+YQ FA  + + + P  WLPGNHD +  M + LQ +GI P  +  +G+ WQ+
Sbjct: 64  LSQDHSAASYQRFARMVTTLQKPVHWLPGNHDHRVLMQNELQVSGIRPEMQ-LVGDHWQV 122

Query: 125 LLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAG 184
           +LLDSQV+G PHG LS  QLE LE  L   PE+H L+ LHHH  P G  WLDQH L+NA 
Sbjct: 123 ILLDSQVYGTPHGWLSHLQLEQLEAALLQYPEKHVLICLHHHTFPIGSIWLDQHDLKNAS 182

Query: 185 ELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWR 244
           +   VLA++P VK +LCGH+HQE D    G R L +PSTC+QF+P   +F+LDT++PGWR
Sbjct: 183 DFLAVLARYPRVKAVLCGHVHQEYDQYHQGIRFLTSPSTCIQFQPLSVDFSLDTMSPGWR 242

Query: 245 TLELHADGTLTTEVHRLADTRFQPDTASEGY 275
            L+L+ DG + T+V RL   +F PD  S GY
Sbjct: 243 YLQLYPDGRIATQVWRLEPGQFAPDLQSTGY 273


>UniRef50_P44685 Protein icc homolog n=27 Tax=Pasteurellaceae RepID=ICC_HAEIN
          Length = 274

 Score =  282 bits (721), Expect = 1e-74,   Method: Composition-based stats.
 Identities = 140/266 (52%), Positives = 186/266 (69%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
           A +  +++LQITD HLF  +   LLGVNT  S+  VL+ I+   +EFD+I+ATGDL QD 
Sbjct: 9   AEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNEFDVILATGDLVQDS 68

Query: 70  SSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDS 129
           S   Y  F E +  F  P  W+PGNHDFQP M   L    ++ AK + +GE WQ LLLDS
Sbjct: 69  SDEGYIRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGEHWQALLLDS 128

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
           QV+GVPHG+LS+ QL+ L+  L   PER+TL++LHHH LP   +WLDQH+LRN+ EL  V
Sbjct: 129 QVYGVPHGQLSQHQLDLLKETLGKNPERYTLVVLHHHLLPTNSAWLDQHNLRNSHELAEV 188

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELH 249
           LA F +VK +L GHIHQE++ +WNG +++ATP+TC+QFKP C  F+LDT+ PGWR +ELH
Sbjct: 189 LAPFTNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQPGWREIELH 248

Query: 250 ADGTLTTEVHRLADTRFQPDTASEGY 275
           +DG++ TEV R+    F P+   EGY
Sbjct: 249 SDGSIRTEVKRIQQAEFFPNMQEEGY 274


>UniRef50_B8HUH6 Metallophosphoesterase n=2 Tax=Chroococcales RepID=B8HUH6_CYAP4
          Length = 266

 Score =  277 bits (708), Expect = 4e-73,   Method: Composition-based stats.
 Identities = 110/261 (42%), Positives = 149/261 (57%), Gaps = 2/261 (0%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + I+Q++DTHLFA     L+G+NT ++ +AVL+ +       DL++ TGDL+QD+S  +Y
Sbjct: 8   LHIVQLSDTHLFADLQGQLVGLNTADALKAVLDQVAQLSPRPDLLLLTGDLSQDESVQSY 67

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
            H  + +A    P  WLPGNHD   AM   L    +      F    WQ LLL+SQV G 
Sbjct: 68  THLRDWLAPLDIPVHWLPGNHDNLQAMAQVLL-PPLYSGPSTFYLGGWQFLLLNSQVPGK 126

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
            +GELS   L WLE  L   P+R +L+ LHH PL     WLD   LRN   L  ++ + P
Sbjct: 127 VYGELSPDTLLWLENNLQAHPDRPSLIALHHPPLSISTPWLDSSRLRNPEPLLELIDRHP 186

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTL 254
            VK +  GHIHQE   +  G   L++PSTCVQF P  S F +D + PG+R L L+ DG  
Sbjct: 187 QVKLVSFGHIHQEFAAERRGVIYLSSPSTCVQFLPCSSQFAIDPMPPGFRRLMLYPDGQF 246

Query: 255 TTEVHRLADTRFQPDTASEGY 275
            TEV R+    +Q D A++GY
Sbjct: 247 HTEVMRVE-FSYQFDLAAQGY 266


>UniRef50_Q1N2L2 Metallophosphoesterase n=1 Tax=Bermanella marisrubri
           RepID=Q1N2L2_9GAMM
          Length = 260

 Score =  275 bits (703), Expect = 1e-72,   Method: Composition-based stats.
 Identities = 107/260 (41%), Positives = 152/260 (58%), Gaps = 2/260 (0%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           + +QITD+HLF+ K   LLG++T  S  AVLE +R    ++D  + TGDL+QD +  +YQ
Sbjct: 3   KFIQITDSHLFSTKPGKLLGMDTQYSLDAVLEKLRDEHCDYDFYLCTGDLSQDGTVESYQ 62

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVP 135
           H    +A    P  W+PGNHD +P M     +      K VF    WQI++LDSQV G  
Sbjct: 63  HLKNTLAKDGKPQHWIPGNHDHRPNMVQVASEE--VEMKPVFRAGAWQIIMLDSQVPGAV 120

Query: 136 HGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPH 195
            G  SE QL+ L   L       TL+ +HHHP+   C WLD   +RN+     ++ ++ +
Sbjct: 121 GGNFSESQLQLLRDALDADSGSPTLVTMHHHPIAMECDWLDTQQIRNSQAFRDIIDQYDN 180

Query: 196 VKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLT 255
           VK +L GH+HQ+ D   NG R ++TPSTCVQF P   +F +DT  PG+R +ELH DG++ 
Sbjct: 181 VKVVLWGHVHQDSDQLINGVRFISTPSTCVQFTPESEDFDVDTCGPGYRWMELHDDGSIK 240

Query: 256 TEVHRLADTRFQPDTASEGY 275
           T V R+    F+ D + +GY
Sbjct: 241 TGVSRVEHIDFEIDYSVKGY 260


>UniRef50_Q4KJ96 Cyclic AMP phosphodiesterase n=25 Tax=Bacteria RepID=Q4KJ96_PSEF5
          Length = 271

 Score =  275 bits (703), Expect = 2e-72,   Method: Composition-based stats.
 Identities = 117/275 (42%), Positives = 159/275 (57%), Gaps = 4/275 (1%)

Query: 1   MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV 60
           M S+    L     V ++Q++D+HLFA+    LLG+NT +S Q V++ +   Q   DL++
Sbjct: 1   MPSV--SALTAADPVLLVQLSDSHLFAETDGTLLGMNTADSLQRVIDLVLAQQPRIDLML 58

Query: 61  ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE 120
           ATGDL+QD +  +YQ F +      AP  WLPGNHD    M  A   +G      V    
Sbjct: 59  ATGDLSQDGTLESYQRFRQLTRQIAAPGRWLPGNHDEPQVMEQA--ASGSDLLDPVVDIG 116

Query: 121 QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL 180
            W+I LLDS V G   G L + QL+ L R L++APERH L+ LHHHP+   C+W++   L
Sbjct: 117 NWRITLLDSAVPGSVPGYLQDEQLQLLTRSLSEAPERHHLVCLHHHPVSIDCAWMEPIGL 176

Query: 181 RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA 240
           RNA  L  V+  FP V+ +L GH+HQE+D      RLLA+PSTC+QF+P   +F ++   
Sbjct: 177 RNAQALFAVIDAFPQVRAVLWGHVHQEIDRLRGDVRLLASPSTCIQFEPLSDDFKVEEQV 236

Query: 241 PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY 275
           PG+R L L  DG L T V R+    F  D  SEGY
Sbjct: 237 PGYRWLRLLPDGRLETGVQRVEGYEFTIDYGSEGY 271


>UniRef50_Q0VLK4 Icc protein, putative n=2 Tax=Alcanivorax RepID=Q0VLK4_ALCBS
          Length = 268

 Score =  274 bits (702), Expect = 2e-72,   Method: Composition-based stats.
 Identities = 107/262 (40%), Positives = 150/262 (57%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
            +R++Q++D HLFA     LLG+NT  S   VLE IR  Q   DLI+ATGDL+QD S  +
Sbjct: 7   PLRVVQLSDCHLFADPEGKLLGLNTQFSLDKVLELIRKEQPNPDLILATGDLSQDASYES 66

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFG 133
           YQ     ++ F  P  WL GNHD    M  AL       +  V     W I++LDS + G
Sbjct: 67  YQRLDRTLSGFDVPVYWLEGNHDKPAPMLQALGAHREKMSPCVLNVGNWTIVMLDSTIPG 126

Query: 134 VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKF 193
              GEL +  L +L+  L DA   H ++ LHHHP+P  C+WLD   + +A +   V+ + 
Sbjct: 127 EVPGELFDGDLSFLDSALRDATGDHLMVCLHHHPVPMECTWLDAQVVGSADKFFQVIDRH 186

Query: 194 PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGT 253
             V+ ++ GH+HQE D   NG R++A PSTCVQFKP   +F +D  +PG+R L+LH +G 
Sbjct: 187 ERVRAIIWGHVHQEYDKHRNGVRMMAVPSTCVQFKPKSEDFAVDDASPGYRWLDLHPNGQ 246

Query: 254 LTTEVHRLADTRFQPDTASEGY 275
           + T V R+    F+ D   +GY
Sbjct: 247 IDTAVSRVEGIPFEVDFTIKGY 268


>UniRef50_B0C4F0 3',5'-cyclic-nucleotide phosphodiesterase n=1 Tax=Acaryochloris
           marina MBIC11017 RepID=B0C4F0_ACAM1
          Length = 265

 Score =  274 bits (700), Expect = 3e-72,   Method: Composition-based stats.
 Identities = 102/267 (38%), Positives = 148/267 (55%), Gaps = 2/267 (0%)

Query: 9   LAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQD 68
           +   + + I Q++D HLFA     LLG+NT+ S +AV++ ++      D ++ TGDLAQD
Sbjct: 1   MKKSSPLLIAQLSDLHLFANPDRDLLGLNTFSSLEAVVQKLKQLPVLPDQLLLTGDLAQD 60

Query: 69  QSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLD 128
           ++  AYQ     IA  + P  WLPGNHD  P M +         A + +    W  LLLD
Sbjct: 61  ETPIAYQQIQSLIAPLQIPTYWLPGNHDHLPTMQATFTAPSF-QAHKSYQMGDWHFLLLD 119

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           S V G  +G LS   L+WL ++L     + TL+ LHH P      WLDQ  L+N+ +L  
Sbjct: 120 SSVTGKVYGGLSPESLDWLNQELEQCDPQPTLIALHHPPFAIKSDWLDQIGLQNSDDLFA 179

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLEL 248
           +L +  HVK ++ GHIHQ+ +        L+TPSTC+QF PH   F LD   PG+R  +L
Sbjct: 180 ILDRHSHVKLVVFGHIHQQFEHQRRSIHYLSTPSTCIQFAPHSKTFALDHAQPGFRLFQL 239

Query: 249 HADGTLTTEVHRLADTRFQPDTASEGY 275
           + DG+  TE+HR+       D +++GY
Sbjct: 240 YGDGSFETEIHRV-MFEKTLDFSAKGY 265


>UniRef50_A1SZX9 Cyclic AMP phosphodiesterase n=2 Tax=Psychromonas
           RepID=A1SZX9_PSYIN
          Length = 278

 Score =  270 bits (691), Expect = 3e-71,   Method: Composition-based stats.
 Identities = 114/270 (42%), Positives = 177/270 (65%), Gaps = 1/270 (0%)

Query: 6   TLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDL 65
            L    +  +++LQITDTHLF+ +++ LLG+   ESY+AV++    +  +   +++TGDL
Sbjct: 10  KLRSDQQGCLQLLQITDTHLFSDRNKDLLGIKPAESYEAVIKHASRYSSKCQAVLSTGDL 69

Query: 66  AQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQIL 125
           +QD +  +Y  F + I +   PC WLPGNHD Q  M  +L   G++ +K++   + WQI+
Sbjct: 70  SQDHTQQSYLDFTKQIKTLNLPCYWLPGNHDTQSVMLPSLLQEGLAQSKQIV-SDFWQII 128

Query: 126 LLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGE 185
           LLDSQV G PHG L+E QL +L++ L + P++HTL+ +HHH LP   +WLDQH L+N  +
Sbjct: 129 LLDSQVEGAPHGFLTEQQLNFLQQALTEYPDKHTLICVHHHVLPVKSAWLDQHILKNNQQ 188

Query: 186 LDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRT 245
              ++    +V+ +L GH+HQ  D+++N  R L +PSTC+QFKP+  +F +D  APG+R 
Sbjct: 189 FLELIKLHKNVRVVLSGHVHQAGDIEFNQVRFLTSPSTCLQFKPNSEDFDVDDSAPGYRY 248

Query: 246 LELHADGTLTTEVHRLADTRFQPDTASEGY 275
           L LH +GT+TT+V R+A   F P+  + GY
Sbjct: 249 LALHKNGTITTKVERVAHGEFSPNKNATGY 278


>UniRef50_Q2S9N2 Predicted phosphohydrolase n=1 Tax=Hahella chejuensis KCTC 2396
           RepID=Q2S9N2_HAHCH
          Length = 267

 Score =  270 bits (691), Expect = 4e-71,   Method: Composition-based stats.
 Identities = 108/269 (40%), Positives = 160/269 (59%), Gaps = 2/269 (0%)

Query: 7   LPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLA 66
           +       + ++Q+TD+HL  +    LLG+NT  S  AVL  +R +    DL++ATGD+A
Sbjct: 1   MASDNNQALTVIQVTDSHLRREPDGTLLGMNTRRSLDAVLSLVRANHENPDLVLATGDIA 60

Query: 67  QDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILL 126
           QD S+ AY+ F E +  F+ P  W  GNHD    M  A+QD       ++F    W+++ 
Sbjct: 61  QDGSTEAYECFHEKMLPFQCPVYWFSGNHDDPGVMAKAVQDPECLAKVKIF--GPWKLIF 118

Query: 127 LDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGEL 186
           LDS V    +G+L++ +L+ L+ +L     +H ++  HHHP+   C+WLD   L N  E 
Sbjct: 119 LDSSVRRKVYGKLAKKELQLLKAELEKDQGKHVIICFHHHPVDVDCAWLDTIGLHNRDEF 178

Query: 187 DTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTL 246
             V+  + HV+ +L GHIHQE D   NG RLLATPSTCVQFKP+  +F +D +APG+R L
Sbjct: 179 FAVIDAYDHVRLVLWGHIHQEYDQVRNGVRLLATPSTCVQFKPYSEDFAVDNLAPGYRWL 238

Query: 247 ELHADGTLTTEVHRLADTRFQPDTASEGY 275
           +L+ DG + T V R +   F+ D +S+GY
Sbjct: 239 KLYPDGRVDTSVVRASHIEFEVDLSSKGY 267


>UniRef50_A1TYT4 Calcineurin phosphoesterase C-terminal domain protein n=3
           Tax=Marinobacter RepID=A1TYT4_MARAV
          Length = 268

 Score =  267 bits (682), Expect = 3e-70,   Method: Composition-based stats.
 Identities = 109/263 (41%), Positives = 154/263 (58%), Gaps = 2/263 (0%)

Query: 13  ARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA 72
             + +LQ+TD HL A    ALLGVNT +S  AV+  +  +  + DLI+ATGDL QD S  
Sbjct: 8   RPLNVLQLTDPHLMASADGALLGVNTRDSLAAVIGEVLRNHGQPDLILATGDLTQDASPE 67

Query: 73  AYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVF 132
           AY++F E + +F  P +W+ GNHD    + +   + G    + +     WQ ++LDS V 
Sbjct: 68  AYRYFGEQLQAFDCPSLWIAGNHDDSALLSAIAAETGSDQKQWI--QGGWQFVMLDSSVH 125

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
           G   GELS  +L +L+R L++ PE   ++ LHHHP+  G  W+++  L+N      V+ +
Sbjct: 126 GKVFGELSADELSFLDRALSERPELPAMVCLHHHPVDIGSDWMEKIGLKNRDAFWQVIDR 185

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADG 252
            P V+ +L GHIHQEL+   NG  LLATPSTC+QF    S+F ++ +APG+R LEL   G
Sbjct: 186 HPQVRVVLWGHIHQELEQQRNGACLLATPSTCIQFATGSSDFAVEPLAPGYRWLELDPSG 245

Query: 253 TLTTEVHRLADTRFQPDTASEGY 275
              TEV R A   F  D  S GY
Sbjct: 246 CFKTEVRRAASFEFDLDEKSTGY 268


>UniRef50_Q8YLG0 3',5'-cyclic-nucleotide phosphodiesterase n=3 Tax=Nostocaceae
           RepID=Q8YLG0_ANASP
          Length = 266

 Score =  265 bits (679), Expect = 9e-70,   Method: Composition-based stats.
 Identities = 94/254 (37%), Positives = 147/254 (57%), Gaps = 1/254 (0%)

Query: 9   LAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQD 68
           +  +  + I QITD HL A + + L G++T ES+ AV++ +   + E DL++ TGDL+ D
Sbjct: 1   MNEKLPISIAQITDIHLLASESQRLQGISTTESFLAVMKRLEELRPELDLLLMTGDLSDD 60

Query: 69  QSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLD 128
            +  +Y++    + S +    WLPGNHD   AM   L + G+   ++ F    W  +LL+
Sbjct: 61  GTPESYENLQHYLNSLQIATYWLPGNHDCAIAMDKIL-NLGMVSRRKSFQRGNWNFILLN 119

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           S V    +G LS   L+WL+ +L   P   TL+ LHH PL    +W+D+  L+N+ EL  
Sbjct: 120 SSVTDCVYGYLSATTLDWLDSELKMLPNNPTLIALHHPPLSVNSAWIDRSCLQNSQELFA 179

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLEL 248
           V+ ++P VK +L GHIHQE     +    L +PSTC QF+   + F ++   PG+R L+L
Sbjct: 180 VIDRYPQVKLVLFGHIHQEFRRQRHNVHYLGSPSTCYQFQSQSTTFAINQELPGFRLLKL 239

Query: 249 HADGTLTTEVHRLA 262
           +ADGT TT++ R+ 
Sbjct: 240 YADGTWTTKIERVP 253


>UniRef50_A4BSE9 Ser/Thr protein phosphatase n=1 Tax=Nitrococcus mobilis Nb-231
           RepID=A4BSE9_9GAMM
          Length = 279

 Score =  264 bits (675), Expect = 2e-69,   Method: Composition-based stats.
 Identities = 105/265 (39%), Positives = 148/265 (55%), Gaps = 1/265 (0%)

Query: 11  GEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQS 70
           G   +R+LQITDTHLFA     L+GV+T  SY  V+E +       DLI+ATGDL  D S
Sbjct: 15  GIGSLRVLQITDTHLFADLSGQLVGVDTERSYAEVMEKVLGEFWPVDLILATGDLVHDGS 74

Query: 71  SAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQ 130
            + Y+ F           + +PGNHD    M        ++ +        WQ ++LDS 
Sbjct: 75  ESGYRRFKSQFEDLAVRTLVIPGNHDDATIMRRIFSTGRVTWSGSAL-LGAWQFVMLDSS 133

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
             G   G L+  QL+ LE+ L   PE H L+ LHHHPL  GC W+D+ ++ N  EL  +L
Sbjct: 134 QLGSAAGHLARSQLQMLEQCLTSYPEHHALVCLHHHPLAIGCDWIDRIAVDNGRELFEIL 193

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHA 250
            +   V+ ++ GH+HQE +   +G RLLA+PSTCVQF+P    FT+D + PG+R L+L+A
Sbjct: 194 DRHEQVRGVVWGHVHQEFETIRHGVRLLASPSTCVQFRPGQQEFTIDDVPPGFRWLQLYA 253

Query: 251 DGTLTTEVHRLADTRFQPDTASEGY 275
           DG + T + R+   +   D   EGY
Sbjct: 254 DGRIKTSIIRVDAAQGGVDLDCEGY 278


>UniRef50_C6AKV1 Icc n=6 Tax=Pasteurellaceae RepID=C6AKV1_AGGAN
          Length = 274

 Score =  264 bits (675), Expect = 3e-69,   Method: Composition-based stats.
 Identities = 135/265 (50%), Positives = 182/265 (68%)

Query: 11  GEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQS 70
            +   RI+QITD HLF   +  LLG+NT  S+  VL  I+  Q+ +DL++ATGDL QD S
Sbjct: 10  QQEVFRIVQITDPHLFKDTNGELLGINTQASFSQVLTEIQQQQYAYDLVLATGDLVQDSS 69

Query: 71  SAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQ 130
              Y HF E + +      W+PGNHDFQP M+  L    IS  K + +G++WQILLLDSQ
Sbjct: 70  DEGYLHFCESVKALEKMVFWIPGNHDFQPKMFDLLTTDNISAKKHILLGDRWQILLLDSQ 129

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
           + GVPHG+LSE+QL+WL  KL + P+R++L++LHHH L    +WLDQH+LRNA EL  +L
Sbjct: 130 ISGVPHGQLSEYQLDWLLAKLKEYPQRYSLVVLHHHILSTHSAWLDQHNLRNAHELAYIL 189

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHA 250
           A F +VK +L GHIHQ++D +W+G +++ATPST +QFKP  + F LDT+ PGWR +ELHA
Sbjct: 190 APFSNVKGILHGHIHQQVDGEWHGYKVMATPSTGIQFKPDSNTFALDTVQPGWREIELHA 249

Query: 251 DGTLTTEVHRLADTRFQPDTASEGY 275
           DG + T V R+    F P+   EGY
Sbjct: 250 DGHIETRVKRIQHKTFLPNLQEEGY 274


>UniRef50_UPI0001698C6A Calcineurin phosphoesterase C-terminal domain protein n=1
           Tax=Endoriftia persephone 'Hot96_1+Hot96_2'
           RepID=UPI0001698C6A
          Length = 279

 Score =  263 bits (672), Expect = 6e-69,   Method: Composition-based stats.
 Identities = 100/264 (37%), Positives = 142/264 (53%), Gaps = 1/264 (0%)

Query: 12  EARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
           +  + +LQ++D+H++A +   L+G+NT +S   V+   R      DL++ATGDL  D S+
Sbjct: 17  DGAITLLQLSDSHIYADQDRCLVGINTQDSLDQVIALARQQLSTPDLLLATGDLVHDASA 76

Query: 72  AAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQV 131
           A YQ  AE +++F  P   LPGNHD    M   L    +           W I+ LDS +
Sbjct: 77  AGYQRIAERLSAFGCPVYCLPGNHDVPKVMQEHLNRPPLYCLP-SLQRGNWSIIFLDSTI 135

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
            G P G L + QLE L   L   P+ HTL+ +HHHP+P G +W+D  +L N   L  +L 
Sbjct: 136 PGKPGGHLDDAQLELLSETLNRHPKHHTLITMHHHPVPVGSAWMDTMALVNPEPLFHLLE 195

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHAD 251
           +   V+ +L GHIHQE D    G RL+ TPSTC+QF      F +D+  PG+R + L   
Sbjct: 196 QHSQVRAVLFGHIHQEFDTKHRGIRLIGTPSTCIQFIAGQDKFGIDSKPPGYRAMVLLES 255

Query: 252 GTLTTEVHRLADTRFQPDTASEGY 275
           G + TEV  L       D +S GY
Sbjct: 256 GEIRTEVRLLQALPLGLDLSSGGY 279


>UniRef50_A4B8Z0 Putative uncharacterized protein n=1 Tax=Reinekea blandensis MED297
           RepID=A4B8Z0_9GAMM
          Length = 263

 Score =  262 bits (669), Expect = 1e-68,   Method: Composition-based stats.
 Identities = 104/261 (39%), Positives = 154/261 (59%), Gaps = 2/261 (0%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
             ++QITD HL A     LLG+NT  S + +++ +     E DL++ATGD+AQD S  AY
Sbjct: 5   FTLVQITDPHLHATSDGTLLGMNTENSLRLIVDRVVNEVPEVDLVIATGDIAQDSSVQAY 64

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
           ++F E I    AP  W+PGNHD +  M +A     +  A+ V+    W I+LLDS V G 
Sbjct: 65  RNFLELIRPISAPMRWIPGNHDSRENMATA--GKDLQHAEPVYELGDWVIILLDSIVPGR 122

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
            +G L   QLE L++ L    +RH L+  HHHP+P    W+DQ  +RN      ++  + 
Sbjct: 123 VYGNLDPDQLELLQKTLDKYQDRHVLIGFHHHPVPMKSRWIDQIGVRNRESFQALVNHYD 182

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTL 254
           +++ ++CGH+HQ+ D   NG R ++TPSTCVQF P   +F +D++ P +RTL LH DG L
Sbjct: 183 NIRAVVCGHVHQDSDQVINGIRYISTPSTCVQFLPKSQDFGIDSLGPAYRTLTLHPDGQL 242

Query: 255 TTEVHRLADTRFQPDTASEGY 275
            T + R+    F+ D + +GY
Sbjct: 243 DTTISRIDGVDFEIDYSQKGY 263


>UniRef50_A0YY40 3',5'-cyclic-nucleotide phosphodiesterase n=1 Tax=Lyngbya sp. PCC
           8106 RepID=A0YY40_9CYAN
          Length = 276

 Score =  260 bits (666), Expect = 3e-68,   Method: Composition-based stats.
 Identities = 98/253 (38%), Positives = 147/253 (58%), Gaps = 2/253 (0%)

Query: 9   LAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQD 68
           +     ++++QI+DTHLFA   + ++G+ T +S  AVL+ IR      D+++ TGDL+QD
Sbjct: 1   MPQTEPIQVIQISDTHLFANPDQKMMGLTTADSLIAVLDRIRQLNINPDVLLITGDLSQD 60

Query: 69  QSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLD 128
           ++S +YQ     I  F     W+PGNHD      S L+   IS  K+ F    W+ +LL+
Sbjct: 61  ETSKSYQQLQALIQPFNTSTYWIPGNHDDLSVAESILKKTPIS-IKKAFNISNWKFILLN 119

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           SQ  G  HGEL+   L  L+ +L   PE+ TL+ LHH P+  G  W+D+  LRN+ +L  
Sbjct: 120 SQCPGKVHGELTPESLNDLDSQLQQHPEQPTLIALHHPPVLIGSEWMDKIKLRNSEDLFA 179

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA-PGWRTLE 247
           V+ ++  VK ++ GHIHQE +   NG      PSTCVQFKP     T D +A PG+R L 
Sbjct: 180 VIDRYSQVKLVIFGHIHQEFETIRNGVVYWGCPSTCVQFKPQSVELTFDQVATPGFRVLT 239

Query: 248 LHADGTLTTEVHR 260
           L+++G   +++ R
Sbjct: 240 LYSNGEYNSKIER 252


>UniRef50_C7R6J1 Metallophosphoesterase n=1 Tax=Kangiella koreensis DSM 16069
           RepID=C7R6J1_KANKD
          Length = 274

 Score =  257 bits (656), Expect = 4e-67,   Method: Composition-based stats.
 Identities = 97/275 (35%), Positives = 148/275 (53%), Gaps = 1/275 (0%)

Query: 1   MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV 60
           M +       G   + +L ++D HLFA    +LLGVNT ES+ AVLE IR    + D+I+
Sbjct: 1   MTNDCKRLFIGRPEMTVLHLSDPHLFADDQGSLLGVNTQESFCAVLEDIRARAIDPDVII 60

Query: 61  ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE 120
            TGD++QD S  +YQ FA+ +A F  P   L GNHD    + S L +A +   K++   +
Sbjct: 61  VTGDISQDYSKDSYQFFAKQMAKFGKPVFTLAGNHDEVEYLTSFLSEAPLFNHKQIL-TD 119

Query: 121 QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL 180
            WQIL++ S +    HG +   +L+W  R L +  +  T++ +HHHP+P G  WLD+  +
Sbjct: 120 HWQILMISSHIEDEVHGRIDPSELKWARRCLEENSDLPTMIYMHHHPVPVGSDWLDEIGV 179

Query: 181 RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA 240
            N  EL  ++ + P VK    GH+HQ  +   +     + PSTCVQFK H ++F      
Sbjct: 180 SNKDELLELVTEHPQVKLCGFGHVHQFSEYKIDNAVYCSVPSTCVQFKRHSADFAASGET 239

Query: 241 PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY 275
           PG+   + HADG +  + +R+       + A  GY
Sbjct: 240 PGYAVYQCHADGVIDKQNYRVDHYLPSVNFAISGY 274


>UniRef50_D2U2B8 Cyclic 3',5'-adenosine monophosphate phosphodiesterase n=4
           Tax=Gammaproteobacteria RepID=D2U2B8_9ENTR
          Length = 265

 Score =  255 bits (653), Expect = 9e-67,   Method: Composition-based stats.
 Identities = 154/265 (58%), Positives = 192/265 (72%), Gaps = 4/265 (1%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +RILQITDTHLFA   + LLGVNT+ S+ AV++AI       DL+VATGDLAQDQS+ AY
Sbjct: 1   MRILQITDTHLFANADDTLLGVNTFASFHAVIDAILVRNENVDLVVATGDLAQDQSAQAY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
           QHFAEGI    APCVWLPGNHD+QPAM + L  AGI P+K++ I + WQIL+LDSQ+ G 
Sbjct: 61  QHFAEGIKRLSAPCVWLPGNHDYQPAMVATLAKAGILPSKQLLINDNWQILMLDSQIQGA 120

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
            HG+LS+ QL W++       ER  LL+LHHHPLP+GC+WLDQH LRN+  L   L ++ 
Sbjct: 121 VHGKLSKQQLLWMKSCFDAYTERSHLLMLHHHPLPSGCTWLDQHRLRNSHILADYLKQYQ 180

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELH----A 250
            +K +LCGHIHQE+D  W G R++ATPSTC+QFKPHC+NFTLDT+ PGWR L+L      
Sbjct: 181 KIKAILCGHIHQEIDEYWQGVRMMATPSTCIQFKPHCTNFTLDTMTPGWRYLDLSINDAG 240

Query: 251 DGTLTTEVHRLADTRFQPDTASEGY 275
           +  L T+V RL   +F PD  S GY
Sbjct: 241 EDVLNTQVCRLDSDKFCPDLDSGGY 265


>UniRef50_B8GLR4 Icc protein n=1 Tax=Thioalkalivibrio sp. HL-EbGR7
           RepID=B8GLR4_THISH
          Length = 266

 Score =  255 bits (652), Expect = 1e-66,   Method: Composition-based stats.
 Identities = 94/257 (36%), Positives = 135/257 (52%), Gaps = 1/257 (0%)

Query: 9   LAGEARVRILQITDTHLFAQKHEALLG-VNTWESYQAVLEAIRPHQHEFDLIVATGDLAQ 67
           ++    + ++QITD HL A         ++T  +   VL  IR    + DL++ATGDLA+
Sbjct: 1   MSRSRPLTVVQITDPHLGAPSEGMYGVTIDTGATLARVLADIRARCPQADLMLATGDLAE 60

Query: 68  DQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLL 127
               A Y    + ++    P   LPGNHD    M  AL DA      RV   E W +++L
Sbjct: 61  RPVPATYAQLRKALSGLPMPVHCLPGNHDEPQVMEEALADAPGIDCARVITREDWVVVML 120

Query: 128 DSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELD 187
           DS + G   G L   +LE+LE  L+  P R+ L+ LHH  +  G  W+D+  L +AG L 
Sbjct: 121 DSTIPGHAGGALDADELEFLEETLSRHPARNALICLHHPVVAVGSRWMDRMKLADAGALF 180

Query: 188 TVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLE 247
            +  +   V+ LL GHIHQ+ +    G RL+ TPSTC+QF P   +F LD + P WR L 
Sbjct: 181 QITDRHTQVRGLLFGHIHQDFEAVRKGVRLIGTPSTCLQFLPESDDFALDALPPAWRHLT 240

Query: 248 LHADGTLTTEVHRLADT 264
           LH DG + T+V  + + 
Sbjct: 241 LHPDGRIDTQVIYVDEP 257


>UniRef50_B7S0L2 Calcineurin-like phosphoesterase C-terminal domain family protein
           n=1 Tax=marine gamma proteobacterium HTCC2148
           RepID=B7S0L2_9GAMM
          Length = 279

 Score =  253 bits (646), Expect = 6e-66,   Method: Composition-based stats.
 Identities = 95/268 (35%), Positives = 139/268 (51%), Gaps = 4/268 (1%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
                VR++QITDTHL A     LL ++T  S + V+E     +   D ++ TGDL+   
Sbjct: 13  TEGDTVRLVQITDTHLCANPGGTLLDMDTDRSLKLVIERALQERGTPDGVLCTGDLSDQG 72

Query: 70  SSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDS 129
           S  AY+     +    AP  WLPGNHD    M +A+            +   WQ++LL+S
Sbjct: 73  SLQAYRRLIAHLQEIPAPDFWLPGNHDDLSEMQAAV--DTSDRLCAEVLAGNWQVILLNS 130

Query: 130 QVFGVPHGELSEFQLEWLERKL--ADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELD 187
           Q+ G   G L   +LE L   L  A A   H+L+ LHH P+  G +W+DQ  + +A +  
Sbjct: 131 QIPGEVGGRLGSDELEKLRLALERAQAEGLHSLVCLHHQPVAIGSAWIDQQMVEDADQFW 190

Query: 188 TVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLE 247
            ++     VK +L GH+HQ++D       L+A+PS+CVQF P  + F  D   PG+R L+
Sbjct: 191 EIVDAASSVKGVLWGHVHQQIDERRGDIALMASPSSCVQFAPGSAMFKADDKPPGYRWLD 250

Query: 248 LHADGTLTTEVHRLADTRFQPDTASEGY 275
           L +DG++ T V R+    F  D  S GY
Sbjct: 251 LCSDGSINTGVSRVTGVDFTVDLESGGY 278


>UniRef50_A6F721 Icc protein-like protein n=1 Tax=Moritella sp. PE36
           RepID=A6F721_9GAMM
          Length = 274

 Score =  252 bits (645), Expect = 7e-66,   Method: Composition-based stats.
 Identities = 129/275 (46%), Positives = 179/275 (65%), Gaps = 1/275 (0%)

Query: 1   MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV 60
           M + ++        + +LQ+TDTHLFA   + LLGV T  SY+ V++AI  +Q  FD ++
Sbjct: 1   MGADISKLTVKHNVINLLQVTDTHLFATAEKDLLGVKTQLSYRHVIDAILQNQQPFDAVL 60

Query: 61  ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE 120
           ATGD++QD + A+YQ+FA+ I     PC WLPGNHD  P M  AL+  G+   K   +  
Sbjct: 61  ATGDISQDNTPASYQYFAQHIKRLNKPCYWLPGNHDNIPLMADALRAEGVLADKY-KVVG 119

Query: 121 QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL 180
            WQI+LLDSQ+ G P G L+  QL  L+ +L+  P++  L++LHH+  P GC WLDQH L
Sbjct: 120 DWQIVLLDSQLTGSPAGYLAPEQLLLLDEQLSAHPDKFALVVLHHNVYPVGCKWLDQHLL 179

Query: 181 RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA 240
           RNA     +LAK P   ++L GH+HQ+LD  + G   +A+PSTC QFKPHC  FTLD  A
Sbjct: 180 RNADAFLAILAKHPQANHVLFGHVHQQLDKTYAGIHFMASPSTCFQFKPHCDEFTLDARA 239

Query: 241 PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY 275
           PGWR L+LH+DG++ ++V RL++  F PD  S+GY
Sbjct: 240 PGWRYLQLHSDGSINSQVWRLSNNDFNPDLESKGY 274


>UniRef50_A4A8X3 Icc protein n=2 Tax=unclassified Gammaproteobacteria
           RepID=A4A8X3_9GAMM
          Length = 278

 Score =  252 bits (644), Expect = 9e-66,   Method: Composition-based stats.
 Identities = 103/266 (38%), Positives = 142/266 (53%), Gaps = 5/266 (1%)

Query: 12  EARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
              VR++Q+TDTHL A     LLG++T  S QAV++ +     + D ++ TGDLA   + 
Sbjct: 15  SETVRVVQLTDTHLKAHDGGKLLGLDTDYSLQAVIDLVNSEYPDPDFVLGTGDLADSGAG 74

Query: 72  AAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQV 131
            AY               WLPGNHD +  M       G            WQI++LDSQ+
Sbjct: 75  DAYNRLIGYFDQVSTEHFWLPGNHDLREVMADV---GGARRLPGEIRVGAWQIVMLDSQL 131

Query: 132 FGVPHGELSEFQLEWLERKLADAPERH--TLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
            G   G L   +L+ LE  LA + E    TL+ +HH P+P GC WLD+  + +A     +
Sbjct: 132 PGEVGGHLGRGELQRLEECLAASAEAGLYTLICMHHQPVPVGCDWLDEQMVSDADSFFEI 191

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELH 249
           L ++P V+ +L GH+HQ LD      RLL TPSTCVQF P  ++F +D+ APG+R LEL 
Sbjct: 192 LGRYPQVRGVLWGHVHQALDQRCEDLRLLCTPSTCVQFLPKQTDFAVDSRAPGYRWLELE 251

Query: 250 ADGTLTTEVHRLADTRFQPDTASEGY 275
            DGT+ T+V R     F  D  + GY
Sbjct: 252 PDGTIRTDVSRAESQIFPVDKEASGY 277


>UniRef50_C5SEA9 Calcineurin phosphoesterase domain protein n=1 Tax=Allochromatium
           vinosum DSM 180 RepID=C5SEA9_CHRVI
          Length = 261

 Score =  251 bits (642), Expect = 2e-65,   Method: Composition-based stats.
 Identities = 95/262 (36%), Positives = 134/262 (51%), Gaps = 2/262 (0%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
            +R+LQ+TD HLF      LLG+ T  S+++VL          D ++ TGDL  D++   
Sbjct: 2   PLRLLQLTDPHLFGDPGGQLLGITTRRSFESVLALALSESPAPDALILTGDLVHDETPVG 61

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFG 133
           Y++  E +     P   + GNHD Q  M   L  A +     +   + W ++ LDS   G
Sbjct: 62  YRYLRERLNRTGIPYYCIGGNHDIQSLMMEQLGPAALVSV-ALRRLDGWNLIFLDSSEPG 120

Query: 134 VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKF 193
              G L+E QL  L   LAD      L+ LHHHP   G +W+D+  + N   L  +  + 
Sbjct: 121 SDGGRLTETQLTQLTDLLAD-ERAPALICLHHHPAAVGSAWIDRIGVANGASLLDLCNRH 179

Query: 194 PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGT 253
           PHVK +L GH+HQE        RLL  P+TC QF+P   +F +D I PG+R L L+ DG 
Sbjct: 180 PHVKAVLFGHVHQEFSAWHGDCRLLGAPATCFQFEPRSRDFAIDEIPPGYRELMLYPDGR 239

Query: 254 LTTEVHRLADTRFQPDTASEGY 275
           LTT V RL +   +P   + GY
Sbjct: 240 LTTRVVRLVEYAERPLYQAGGY 261


>UniRef50_Q7MNX9 Cyclic AMP phosphodiesterase n=60 Tax=Gammaproteobacteria
           RepID=Q7MNX9_VIBVY
          Length = 274

 Score =  251 bits (641), Expect = 2e-65,   Method: Composition-based stats.
 Identities = 138/265 (52%), Positives = 188/265 (70%)

Query: 11  GEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQS 70
            E  +++LQITDTHLFA    +LL V T +S+QAV+E +     EFD ++ATGD++QD S
Sbjct: 10  SENSIKLLQITDTHLFASDEGSLLSVKTLQSFQAVVEQVMARHVEFDYLLATGDISQDHS 69

Query: 71  SAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQ 130
           +A+YQ FA+GIA     C WLPGNHD++P M S L    I+  ++V +   WQ++LLDSQ
Sbjct: 70  AASYQRFADGIAPLEKACFWLPGNHDYKPNMSSVLPSPQITTPEQVELNAHWQLILLDSQ 129

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
           V GVPHG LS+ QL  LE  L  +PE++TL+LLHHHPL  G +WLDQH+L++A     ++
Sbjct: 130 VVGVPHGRLSDQQLSMLEHHLQASPEKNTLILLHHHPLLVGSAWLDQHTLKDAEAFWQIV 189

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHA 250
            +FP VK ++CGH+HQ++++   G R++ATPSTCVQFKP   +F LDT++PGWR L LHA
Sbjct: 190 ERFPMVKGIVCGHVHQDMNVMHKGIRVMATPSTCVQFKPQSDDFALDTVSPGWRELTLHA 249

Query: 251 DGTLTTEVHRLADTRFQPDTASEGY 275
           +G +TT+V RLA   F PD  S GY
Sbjct: 250 NGEITTQVQRLASGSFLPDFTSSGY 274


>UniRef50_Q12J78 Metallophosphoesterase n=21 Tax=Shewanella RepID=Q12J78_SHEDO
          Length = 279

 Score =  247 bits (632), Expect = 3e-64,   Method: Composition-based stats.
 Identities = 114/275 (41%), Positives = 167/275 (60%), Gaps = 5/275 (1%)

Query: 5   LTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGD 64
           ++  +     VR++Q+TD HLFA     LLGV T++S+ AVL  I    H   L++ATGD
Sbjct: 6   VSYSITESDTVRLVQVTDPHLFADLEAQLLGVTTYQSFSAVLAMINQANHGQHLLLATGD 65

Query: 65  LAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQI 124
           L+QD S  +YQ FA  +     PC +LPGNHD    M  ++Q   +   +R+    QWQI
Sbjct: 66  LSQDYSPESYQLFANTVKRVPVPCHYLPGNHDDARLMNLSVQGDHVFGQQRII-IGQWQI 124

Query: 125 LLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAG 184
           L+L+S + G P G L+  Q   +++ +A AP++H LL +HH+P+   C+WLDQH + N  
Sbjct: 125 LMLNSTLIGKPGGYLAPSQFTLIKQAIAQAPDKHVLLAMHHNPVLVDCAWLDQHCMANGE 184

Query: 185 ELDTVLAKFPHVKYLLCGHIHQELDLDWNG----RRLLATPSTCVQFKPHCSNFTLDTIA 240
           EL     +F  +K L+ GH+HQ LD    G     +L+ATPSTC+QFKP  ++F LD + 
Sbjct: 185 ELIDFAGQFKQIKGLVWGHVHQALDRQVLGQFGPIKLMATPSTCIQFKPKSAHFALDGLQ 244

Query: 241 PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY 275
           PG+R L+L +DG++ T+V+RLA   F  D  + GY
Sbjct: 245 PGYRLLDLASDGSIHTQVYRLAGDEFSADNHANGY 279


>UniRef50_A3M1D0 Cyclic 3'5'-adenosine monophosphate phosphodiesterase n=17
           Tax=Acinetobacter RepID=A3M1D0_ACIBT
          Length = 270

 Score =  247 bits (631), Expect = 3e-64,   Method: Composition-based stats.
 Identities = 93/259 (35%), Positives = 134/259 (51%), Gaps = 3/259 (1%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           I+QITDTHL        +G+N  ES+ A+++ I     E D I+ TGDLAQ  +   Y+ 
Sbjct: 15  IIQITDTHLLEYPQLEFVGMNPEESFHAIIQQILKQHPEADAIIHTGDLAQAPTPITYKR 74

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPH 136
           +   + +   P     GNHD         ++        V     W++++L+S V G   
Sbjct: 75  YINFMQTLGLPFFQTLGNHDNVDHFPLHNENHQQPV---VVGLGNWRVIMLNSAVKGKVD 131

Query: 137 GELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHV 196
           G LS  QLE L   L    +   LL  HHHP      W+D H L+N+  L   L+ F +V
Sbjct: 132 GHLSSEQLENLANLLEQFADHPVLLACHHHPFAMKSKWIDHHKLQNSNALLDTLSPFQNV 191

Query: 197 KYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTT 256
           K L+CGH+HQ+    W G    +TPST VQFKP  ++F LD  APG+R + L+ DG+  T
Sbjct: 192 KALVCGHVHQDSLNIWQGIEFFSTPSTSVQFKPFSNDFALDQNAPGYRYIRLNNDGSFET 251

Query: 257 EVHRLADTRFQPDTASEGY 275
           +V RL + + + +T   GY
Sbjct: 252 KVFRLENFKTRINTDISGY 270


>UniRef50_B5JTJ8 Metallophosphoesterase n=1 Tax=gamma proteobacterium HTCC5015
           RepID=B5JTJ8_9GAMM
          Length = 250

 Score =  245 bits (626), Expect = 1e-63,   Method: Composition-based stats.
 Identities = 85/251 (33%), Positives = 127/251 (50%), Gaps = 2/251 (0%)

Query: 13  ARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA 72
           +  R+LQ++D H+ A     L G +T E  + +LE I+     F  ++ +GDL+   S+ 
Sbjct: 2   STQRLLQLSDCHITADADTQLRGYDTHELLRKLLEQIKKRDRHFHALLLSGDLSDRGSAE 61

Query: 73  AYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVF 132
           +YQ     ++  + P   LPGNHD    M   L+   I+          W++L+L+SQ  
Sbjct: 62  SYQRLNALLSFCKKPIYALPGNHDQLLEMRDQLRK--IAQCVHSADLGTWRLLMLNSQQA 119

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
           G   G LSE +L  L+  L       +L+ +HH P     +W+D  +L+N  EL  ++  
Sbjct: 120 GKTEGYLSEDELSRLKLWLDHGKNIPSLVAVHHPPCSIHSAWMDAINLQNGDELLDIVKS 179

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADG 252
              VK +  GH+HQ  D   +G RLL TPSTC QF P    F +D   PG+R  ELH +G
Sbjct: 180 HHQVKAISFGHVHQAFDQTIHGVRLLGTPSTCFQFTPERDEFDIDDKPPGYRWFELHDNG 239

Query: 253 TLTTEVHRLAD 263
              T+V  L D
Sbjct: 240 EFDTDVTWLGD 250


>UniRef50_A0Y9K0 Cyclic AMP phosphodiesterase n=1 Tax=marine gamma proteobacterium
           HTCC2143 RepID=A0Y9K0_9GAMM
          Length = 276

 Score =  245 bits (625), Expect = 2e-63,   Method: Composition-based stats.
 Identities = 106/272 (38%), Positives = 157/272 (57%), Gaps = 3/272 (1%)

Query: 5   LTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGD 64
           L +P+     +++LQITDTHL AQ  E LLG+NT  S + V++ +R  +   DL++ATGD
Sbjct: 7   LLVPIDSHQPIKLLQITDTHLGAQAAETLLGLNTDYSLEQVVDLVRRERPHADLLLATGD 66

Query: 65  LAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQI 124
           ++   +  +Y  + +         +WLPGNHD   AM  A    G   A        W I
Sbjct: 67  ISSCGAGQSYHRYRQLTKGIADQTLWLPGNHDTVAAMREA-AKDGNEMAGCA-TIGNWHI 124

Query: 125 LLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAG 184
           ++L+S+  G   G LS+ +L  L   L  + E + L+ LHHHP+  GC WLD+  + NA 
Sbjct: 125 IMLNSKTPGKVGGSLSDKELAKLRVGLQQSREGYALVCLHHHPVSIGCDWLDEQKVSNAE 184

Query: 185 ELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWR 244
            L +VL +F HV+ LL GH+HQ++D   NG +L+ATPSTC+QF    ++F LD ++PG+R
Sbjct: 185 TLFSVLDEFTHVRGLLWGHVHQQIDQQRNGVKLMATPSTCIQFAADSADFKLDRLSPGYR 244

Query: 245 TLELHADGTLTTEVHRLADTRFQPDT-ASEGY 275
            L+L  +G + T V R++   F  D   S GY
Sbjct: 245 WLDLQENGDIETGVSRVSGVVFDIDYDDSSGY 276


>UniRef50_Q606D3 Cyclic AMP phosphodiesterase n=1 Tax=Methylococcus capsulatus
           RepID=Q606D3_METCA
          Length = 259

 Score =  244 bits (623), Expect = 2e-63,   Method: Composition-based stats.
 Identities = 101/257 (39%), Positives = 142/257 (55%), Gaps = 3/257 (1%)

Query: 9   LAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQD 68
           +     + +LQ+TD+H+         G ++  S  AV++        FDL++ TGDLAQ+
Sbjct: 1   MPDSGTLCLLQLTDSHILPDAESRFYGSDSAASLGAVIDHANQR--RFDLVLFTGDLAQE 58

Query: 69  QSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLD 128
               +Y+  A   A+  APC WLPGNHD        L+   +   + V    +W I+ LD
Sbjct: 59  PVPQSYRRLAGICAALPAPCHWLPGNHDEPALARHVLESTPL-LHQPVIRRGRWLIVCLD 117

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           S V G   G LS  Q + LER L+  P  HTL+ LHHHP+P+G +W+D   L NAGE   
Sbjct: 118 STVPGSAGGSLSTGQFDLLERTLSRHPSLHTLVALHHHPVPSGSAWMDTMILDNAGEFFA 177

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLEL 248
           VL + P VK ++ GH HQ  D++  G R+L TPSTC+QF+P    F LD   PG+R LEL
Sbjct: 178 VLRRHPQVKAVVHGHTHQVADVEIEGTRVLGTPSTCIQFRPASQTFALDAERPGYRWLEL 237

Query: 249 HADGTLTTEVHRLADTR 265
             DG++ T + R+A   
Sbjct: 238 GPDGSVATGICRVAVPP 254


>UniRef50_Q21NU3 Metallophosphoesterase n=3 Tax=Gammaproteobacteria
           RepID=Q21NU3_SACD2
          Length = 271

 Score =  242 bits (619), Expect = 7e-63,   Method: Composition-based stats.
 Identities = 108/265 (40%), Positives = 153/265 (57%), Gaps = 7/265 (2%)

Query: 13  ARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA 72
             +R++QITD HL +Q  E +LG++T +S   VLE I+  +   DLI+ATGD++ D  +A
Sbjct: 12  RPLRVVQITDCHLGSQPGELMLGLDTDQSLFDVLELIQNSEPTPDLILATGDISNDGGAA 71

Query: 73  AYQHFAEGIASF--RAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQ 130
           +YQ F + +  +       WLPGNHD    M        I P +  +  + W ++LLDS+
Sbjct: 72  SYQRFIDIVNHYFPGVALAWLPGNHDDPLNMDQV----DILPIEAHYRAQGWNLILLDSR 127

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
           +     GEL   +L  L+ +L    E  T++ LHH P+P G  W+DQ+ ++NA     VL
Sbjct: 128 IPMEEGGELHPNELMRLDAELKANSE-PTMVFLHHQPVPVGSEWIDQYVVKNAEAFFDVL 186

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHA 250
            K+ HVK +  GH+HQE     N   LLATPSTCVQF P    F LDTI PG+R+  L+A
Sbjct: 187 DKYDHVKAVSWGHVHQEFQDSRNNVTLLATPSTCVQFAPKSKPFKLDTIMPGYRSYSLNA 246

Query: 251 DGTLTTEVHRLADTRFQPDTASEGY 275
           DG+ T+EV R+    +  D AS GY
Sbjct: 247 DGSFTSEVKRIQTKAYAIDFASTGY 271


>UniRef50_Q3JEM1 Metallophosphoesterase n=2 Tax=Nitrosococcus oceani
           RepID=Q3JEM1_NITOC
          Length = 270

 Score =  237 bits (605), Expect = 3e-61,   Method: Composition-based stats.
 Identities = 97/271 (35%), Positives = 137/271 (50%), Gaps = 4/271 (1%)

Query: 1   MESLLTLPLAGEAR--VRILQITDTHLFAQKHEALLG-VNTWESYQAVLEAIRPHQHEFD 57
           M SL  L +A +    + +LQ+TD+HL A     L   +NT  S  AVL  I+      D
Sbjct: 1   MTSLPHLKIANDRSEFINVLQLTDSHLLADSEAFLWNDLNTRRSLVAVLNHIQQQGLLGD 60

Query: 58  LIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVF 117
           L+V +GD+A+     AY    E       P   LPGNHD    M   L    +S  + + 
Sbjct: 61  LMVISGDIAEKAEPEAYYWLLERCQELGLPVYCLPGNHDDPVLMDEILNGMNVS-TESLV 119

Query: 118 IGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQ 177
             + WQ++ L+S V    HG LS+ QL +L R LAD+ + +TL+ LHH P+  G  W+D 
Sbjct: 120 TLKNWQLIFLNSVVTQRSHGHLSKGQLGFLNRSLADSLDLNTLIFLHHPPVALGSPWMDA 179

Query: 178 HSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLD 237
             + NA +   VL  +P V+ +  GH HQE   +  G +LL +PSTCVQF P   +F LD
Sbjct: 180 MGVDNAADFFAVLDLYPQVRGVAWGHAHQEFHTERQGVQLLGSPSTCVQFVPGSEHFQLD 239

Query: 238 TIAPGWRTLELHADGTLTTEVHRLADTRFQP 268
              PG+R L L   G + T V+ +       
Sbjct: 240 QRGPGYRWLILLPGGQIETRVYYVDCPPPAR 270


>UniRef50_Q2JPZ0 Icc protein n=2 Tax=Synechococcus RepID=Q2JPZ0_SYNJB
          Length = 264

 Score =  233 bits (594), Expect = 6e-60,   Method: Composition-based stats.
 Identities = 102/264 (38%), Positives = 143/264 (54%), Gaps = 3/264 (1%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
            V ++QI+D HLFA+ H  LLGV+T  S+  V +AI       DL++ TGDL+QD S+A+
Sbjct: 2   TVYVVQISDLHLFAKPHHRLLGVDTEASFLQVQKAIAALDPLPDLLLLTGDLSQDGSAAS 61

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFG 133
           Y      + +      WL GNHD    M   L    +    + F  E W  +LL+S V G
Sbjct: 62  YARLRAHLQALPIDTYWLAGNHDRLHTMNQELHAERLF-GDKSFSRENWSFILLNSLVPG 120

Query: 134 VPHGELSEFQLEWLERKL--ADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
              G L+E  L WL ++L  + A + H LL LHH P     +WLDQ +L+    L  VL 
Sbjct: 121 KDSGYLTERTLLWLRQELQRSKAAQHHVLLALHHPPFSVDSAWLDQSALQQPERLFGVLD 180

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHAD 251
           +F H++ ++ GHIHQ+L     G   LA PSTCVQF+P    F L+ I P  R + L  D
Sbjct: 181 EFDHIRLVVFGHIHQDLHRRREGVDYLACPSTCVQFRPKSPQFGLEVIPPALRQIWLERD 240

Query: 252 GTLTTEVHRLADTRFQPDTASEGY 275
           G+  T+V R+     +P+ A +GY
Sbjct: 241 GSFKTQVQRVGAALQRPNLALKGY 264


>UniRef50_Q2KTW6 cAMP phosphodiesterase n=5 Tax=Bordetella RepID=Q2KTW6_BORA1
          Length = 270

 Score =  232 bits (593), Expect = 7e-60,   Method: Composition-based stats.
 Identities = 99/265 (37%), Positives = 141/265 (53%), Gaps = 7/265 (2%)

Query: 4   LLTLPLAG-EARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVAT 62
           +   PLA  +A   +LQ++D+HL A     +LGVNT  S +AV++  R  + + +L++ T
Sbjct: 1   MPEHPLAAHDAPALLLQLSDSHLMADPDARMLGVNTDASLRAVIDLARRQEGQPELMLLT 60

Query: 63  GDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQW 122
           GDLAQD S  AY+     +    AP   LPGNHD    M   L D        V+    W
Sbjct: 61  GDLAQDGSPQAYRRLQAHLR--GAPVRCLPGNHDAPEVMRQILADW----ISPVYDLPGW 114

Query: 123 QILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRN 182
           +I++LDS V G   G L E QL  L++ + DA  RH L+ LHH+      +W D   + N
Sbjct: 115 RIIMLDSTVPGEDFGHLDEAQLAVLDQAIKDAGPRHVLVALHHNLARVDGNWQDPMMVDN 174

Query: 183 AGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPG 242
           A  +   L+  P  +  L GHIHQE D   +  RLL TPSTC QF  +     +D  APG
Sbjct: 175 AAAVFARLSAHPQTRIALWGHIHQEFDCRHHHLRLLGTPSTCFQFTLNNGQHAIDAKAPG 234

Query: 243 WRTLELHADGTLTTEVHRLADTRFQ 267
           +R ++L+ADG++ T + RL    + 
Sbjct: 235 YRWIKLYADGSIATGIRRLDAAAWA 259


>UniRef50_Q2KTP2 Putative phosphohydrolase n=1 Tax=Bordetella avium 197N
           RepID=Q2KTP2_BORA1
          Length = 271

 Score =  231 bits (590), Expect = 2e-59,   Method: Composition-based stats.
 Identities = 65/267 (24%), Positives = 117/267 (43%), Gaps = 8/267 (2%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + I QI+D H+   + +A   V T       +  +       D+I+ +GDL      A Y
Sbjct: 1   MLIAQISDLHIRLPRQKAYRVVETDRYLPPAVATLNALDPAPDVIILSGDLTDFGRPAEY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGI---SPAKRVFIGEQWQILLLDSQV 131
            H  E +A  + P   +PGNHD + ++ +A  D         +        ++++LD+  
Sbjct: 61  THLRELLAPLQTPFYLMPGNHDARDSLRAAFPDHPYLQGEFIQYTVEHFPLRLIMLDTVE 120

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHS-LRNAGELDTVL 190
               HG L   +L WLE +LA+AP R TL+ +HH P   G + +D+   L+ A EL+ ++
Sbjct: 121 PMQSHGVLCARRLNWLEERLAEAPGRPTLIAMHHPPFQTGIAHMDKIGLLQGAKELEALV 180

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPH---CSNFTLDTIAPGWRTLE 247
            ++ +++ ++ GH+H+ +   + G       ST  Q             +   P +  L 
Sbjct: 181 RRYDNIERIVSGHLHRTIFQRFGGTIASTCASTAHQVVLDLRPEGPSAFNFEPPAYH-LH 239

Query: 248 LHADGTLTTEVHRLADTRFQPDTASEG 274
           L  +G L T    + +         +G
Sbjct: 240 LWRNGQLITHHAYIGNYPGPYPFHEDG 266


>UniRef50_A0Z341 Metallophosphoesterase n=1 Tax=marine gamma proteobacterium
           HTCC2080 RepID=A0Z341_9GAMM
          Length = 275

 Score =  231 bits (589), Expect = 2e-59,   Method: Composition-based stats.
 Identities = 92/269 (34%), Positives = 132/269 (49%), Gaps = 7/269 (2%)

Query: 9   LAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQD 68
           L     + ++Q+TD HL   +   LL V+T +S  AVLE +       D ++ TGD+A D
Sbjct: 11  LNNGDTLTLVQVTDAHLMGVRGGRLLNVDTDDSLAAVLELVEARPEPPDALLITGDIAGD 70

Query: 69  QSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLD 128
            +  AYQ FA+ + +  AP  WLPGNHD                  R      W +++LD
Sbjct: 71  GAGDAYQRFAQALEAIPAPSFWLPGNHDDCDE-----SVVDRERFIRTVTNPHWLVVMLD 125

Query: 129 SQVFGVPHGELSEFQLEWLERKLADA--PERHTLLLLHHHPLPAGCSWLDQHSLRNAGEL 186
           SQ      G L+  +L+ L + +  A    +H L+ LHH   P GC WLD   + N+   
Sbjct: 126 SQQTDEVGGYLAANELDALSQAVDRANQEGKHLLVALHHPLQPVGCDWLDPQRVANSSAF 185

Query: 187 DTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTL 246
           +  + +  +   ++ GH+HQE D      R L TPSTC+QF P+  NF +   APG+R L
Sbjct: 186 ELEVQRCRNQVVVIAGHVHQESDQVSGNIRYLTTPSTCIQFAPNQVNFKVGDQAPGYRWL 245

Query: 247 ELHADGTLTTEVHRLADTRFQPDTASEGY 275
            L   G + T V R+ D  F  D  S GY
Sbjct: 246 RLAPSGEIETGVERVTDREFPVDLDSGGY 274


>UniRef50_B9ZKN4 Calcineurin phosphoesterase domain protein n=1 Tax=Thioalkalivibrio
           sp. K90mix RepID=B9ZKN4_9GAMM
          Length = 265

 Score =  229 bits (584), Expect = 1e-58,   Method: Composition-based stats.
 Identities = 87/265 (32%), Positives = 132/265 (49%), Gaps = 4/265 (1%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGV-NTWESYQAVLEAIRPHQHEFDLIVATGDLAQD 68
                 R++QI+DTHL         G  ++    + +L A+ P +   D ++ +GDLA+D
Sbjct: 3   TMSTTQRLIQISDTHLGRVPGPIRAGYPDSDTQLERILGAL-PREPAADALLLSGDLAED 61

Query: 69  QSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLD 128
              A Y   A  + S R P + L GNHD    + +AL+           +   W+++ LD
Sbjct: 62  PEPATYARLARLLGSRREPMLALAGNHDDCQTLRTALEPETC-QVHGERMLGPWKLIGLD 120

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           S   G   G L   + E LE+ L+  P+R T++ LHH P+  G +W+D+  L +   L  
Sbjct: 121 SSTPGEAAGRLDASECERLEKSLSADPDRPTVVALHHPPVAIGSAWMDRLGLLDPDALFA 180

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTI-APGWRTLE 247
           VL + P V+  L GHIHQ+         LL +PSTCVQF P    F +D     G+R L+
Sbjct: 181 VLDRHPQVRACLFGHIHQDFRARRGAIELLGSPSTCVQFTPGSEEFAVDAALDAGYRILD 240

Query: 248 LHADGTLTTEVHRLADTRFQPDTAS 272
           LH DG   T+V R+  TR   + ++
Sbjct: 241 LHPDGRFDTQVVRVPGTRIAMEPSA 265


>UniRef50_B1XQ99 Putative 3',5'-cyclic-nucleotide phosphodiesterase n=1
           Tax=Synechococcus sp. PCC 7002 RepID=B1XQ99_SYNP2
          Length = 255

 Score =  228 bits (583), Expect = 1e-58,   Method: Composition-based stats.
 Identities = 90/254 (35%), Positives = 122/254 (48%), Gaps = 9/254 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           V I QITDTHL       + GV T  S+QAVL A++  + +   ++ TGDLA    + +Y
Sbjct: 2   VLIAQITDTHLLDHPEAEMRGVKTDASFQAVLAAVQQFKPDR--LILTGDLAHHGEAISY 59

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDS--QVF 132
           +   + + + + P  WLPGNHD    M   LQ   +SP K V     W++LLLDS  +  
Sbjct: 60  ERLRDLVEATQIPSYWLPGNHDDPELMAGILQGDYLSPDKNV-ALGNWKLLLLDSFLENP 118

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
               G L   QL WL  +L         + +HHH +PAG  WLDQ  + N  E   ++  
Sbjct: 119 EYGEGFLDTAQLAWLAERLEHHQNSPVAIAIHHHVVPAGVDWLDQIDMTNRAEFWQIVQH 178

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDT----IAPGWRTLEL 248
            P VK +  GH+H E  +   G     TPSTC Q  P               PG+R  EL
Sbjct: 179 HPQVKTVFFGHVHLEYSVTQGGIPCFGTPSTCTQVTPPDQEPIEGDRQLWEQPGFRLFEL 238

Query: 249 HADGTLTTEVHRLA 262
           H DG   T+V R+ 
Sbjct: 239 HDDGRFQTKVQRIP 252


>UniRef50_B8KUM1 Cyclic AMP phosphodiesterase n=1 Tax=gamma proteobacterium NOR51-B
           RepID=B8KUM1_9GAMM
          Length = 277

 Score =  228 bits (581), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 102/265 (38%), Positives = 144/265 (54%), Gaps = 7/265 (2%)

Query: 13  ARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA 72
           A +++LQITDTHL  Q+   LL V+T  S  AV+  +       D ++ TGD+A   +  
Sbjct: 17  ATLKLLQITDTHLMQQRGGRLLNVDTDASLSAVVA-LASQSLPADALLITGDIAGAGAGD 75

Query: 73  AYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVF 132
           AY    E ++  +AP  WLPGNHD   A    L        KR  I   WQ+L+LDSQV 
Sbjct: 76  AYYRLEEALSPLQAPSFWLPGNHDDGHACADELS----WHFKRQVIFPHWQVLMLDSQVR 131

Query: 133 GVPHGELSEFQLEWLERKLAD--APERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
           G   G L++ +L+ L   +++  A  RH L+ LHH   P GC WLD   + NA ++   L
Sbjct: 132 GEVGGILAQAELDALVTAVSESNASGRHLLVALHHPLWPLGCDWLDSQRVANADDVAACL 191

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHA 250
               +   ++ GH+HQE D    G R L TPSTC+QF  +  +F +D   PG+R L+L A
Sbjct: 192 EMAENKVVVISGHVHQESDAIHRGARYLTTPSTCIQFAKYSPDFKVDDSGPGYRWLDLQA 251

Query: 251 DGTLTTEVHRLADTRFQPDTASEGY 275
           DG ++T V R+ +  F  D  S+GY
Sbjct: 252 DGFVSTGVERVTEVSFPVDLDSDGY 276


>UniRef50_B1KBF2 Metallophosphoesterase n=5 Tax=Proteobacteria RepID=B1KBF2_BURCC
          Length = 266

 Score =  227 bits (578), Expect = 4e-58,   Method: Composition-based stats.
 Identities = 67/263 (25%), Positives = 115/263 (43%), Gaps = 8/263 (3%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           I Q++D H+          V++   + A ++++   + E DL+V +GDL  + +   Y+ 
Sbjct: 4   IAQLSDIHVRPHGVLYQDAVDSNAMFSAAVDSLNRIRPEPDLVVISGDLTDEGTEGEYRK 63

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAK----RVFIGEQWQILLLDSQVF 132
             E +   R P V LPGNHD +  + +A  D    P +          + +++ LD+ V 
Sbjct: 64  LRELLVELRRPFVVLPGNHDDRGNLRAAFPDHAWLPDEGALSFALDVGELRLVALDTSVP 123

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
           G+ HGEL    L WL+ +LA+   R  ++++HH P   G  +LD + LRNA     VLA+
Sbjct: 124 GLHHGELGAETLAWLDTELAEHRNRTVVIVMHHPPFMTGIPYLDIYGLRNAEAFAAVLAR 183

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFK---PHCSNFTLDTIAPGWRTLELH 249
             +V  +L GH+H+ +        +L  PST  Q        +        P +      
Sbjct: 184 HDNVDRILAGHVHRSMQTRLGRVPVLTCPSTITQIALRVEADAQPASFLEPPAYMLHRWA 243

Query: 250 ADGT-LTTEVHRLADTRFQPDTA 271
             G    + +  +         A
Sbjct: 244 GRGQPAVSHLCYVGHFEGPFPFA 266


>UniRef50_Q1YUP4 CAMP phosphodiesterase n=1 Tax=gamma proteobacterium HTCC2207
           RepID=Q1YUP4_9GAMM
          Length = 261

 Score =  223 bits (569), Expect = 5e-57,   Method: Composition-based stats.
 Identities = 101/263 (38%), Positives = 138/263 (52%), Gaps = 3/263 (1%)

Query: 13  ARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA 72
           + V I QITD HL A + E L GV T+ES+ A L+A         L++ TGDLA D  + 
Sbjct: 2   STVHITQITDLHLGADEQETLGGVTTFESFNAALQASEDQGRADSLLLLTGDLASDYQAG 61

Query: 73  AYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVF 132
           AYQ   + +       +WLPGNHD    M + L      P  R++    W ILLLDS   
Sbjct: 62  AYQLLNKVLTEKHRQALWLPGNHDHLETMEANLTA---FPRVRIYEAGAWGILLLDSSKA 118

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
           G P G  SE +L++ E+ L     +  L+ +HH P+    +WLDQ  + N   L  +L  
Sbjct: 119 GQPGGHFSEAELQFAEQGLKHLAGKFVLVAVHHSPVRVNSAWLDQQQIDNHHRLYDLLVA 178

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADG 252
              VK ++ GH+HQ  D  W    + +TPS+CVQF+ H  +F L    PG+R L+LH DG
Sbjct: 179 HGQVKAVVTGHVHQHHDSLWGDLPVYSTPSSCVQFEQHSHDFGLADKPPGYRWLDLHDDG 238

Query: 253 TLTTEVHRLADTRFQPDTASEGY 275
           +L T V  L D   Q D +  GY
Sbjct: 239 SLDTGVEFLKDFAQQCDRSCAGY 261


>UniRef50_Q0EZ19 Ser/Thr protein phosphatase n=1 Tax=Mariprofundus ferrooxydans PV-1
           RepID=Q0EZ19_9PROT
          Length = 265

 Score =  222 bits (565), Expect = 1e-56,   Method: Composition-based stats.
 Identities = 95/259 (36%), Positives = 138/259 (53%), Gaps = 3/259 (1%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
            +++L I+D+HL++     L G+   +S+ AVL          D ++  GD+AQD+    
Sbjct: 2   SLQLLHISDSHLYSDPASLLKGIRPHDSFTAVLADAYRSFPVVDAVILGGDMAQDEQPET 61

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV--FIGEQWQILLLDSQV 131
           Y      +  ++AP +  PGNH     +   L  A  +        +  +WQI+ L+S  
Sbjct: 62  YHRLVSMLPDWQAPMMLTPGNHAALGYLSGTLIPALRARGAYSDRLLSGRWQIITLNSHH 121

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
            G   G L   +LE L++ L+ +   HTL+ LHHHP+P G  WLD+  L N   L  ++ 
Sbjct: 122 PGHISGLLPASELERLQQLLSVSAGIHTLIALHHHPIPIGSRWLDEIDLVNRDALWEIVH 181

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHAD 251
           K  HV+ LLCGHIHQ  D   +G R+L +PSTCVQF P   NF L  I+PG+R LEL  D
Sbjct: 182 KHSHVRALLCGHIHQSFDTIHDGVRVLGSPSTCVQFTPGTDNFALADISPGYRWLELLDD 241

Query: 252 GTLTTEVHRLADTRFQPDT 270
           G ++T VHR+      PD 
Sbjct: 242 GNISTTVHRITGF-IPPDL 259


>UniRef50_Q3JU10 Ser/Thr protein phosphatase family protein n=72 Tax=Burkholderiales
           RepID=Q3JU10_BURP1
          Length = 325

 Score =  221 bits (564), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 59/260 (22%), Positives = 100/260 (38%), Gaps = 9/260 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + +  I+D H+      A   V+T       +  +   +   D ++ TGDL        Y
Sbjct: 52  MLLAHISDLHIKRPGALAYRRVDTAAHLARCVARLNALEPRPDAVLVTGDLTDFGDDDEY 111

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDA----GISPAKRVFIGEQWQILLLDSQ 130
            H    +A    P   L GNHD + AM  A             +        +++ LDSQ
Sbjct: 112 AHLKALLAPLAMPYYLLVGNHDDRAAMRRAFPARVELQSGEFVQYALDLGPLRVIALDSQ 171

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLR--NAGELDT 188
           + G   G L + +L WL  +L  A +R  ++ LHH P   G   +D   L    +  LD 
Sbjct: 172 IPGASGGTLCDARLAWLADQLDAARDRPVIVALHHPPFACGIGHMDAMRLAPDASSRLDA 231

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNF---TLDTIAPGWRT 245
           +L + P+V+ +LCGH+H+ +   + G    A P+   Q      +    +     P +  
Sbjct: 232 LLRRHPNVERVLCGHVHRTMFARFGGTIASAVPAPAHQVTFDLRDGGPSSFSMEPPAFAV 291

Query: 246 LELHADGTLTTEVHRLADTR 265
                   L +    +  + 
Sbjct: 292 HRHAPGAGLASHHVYVDASD 311


>UniRef50_B6R8M8 Ser/Thr protein phosphatase family protein n=1 Tax=Pseudovibrio sp.
           JE062 RepID=B6R8M8_9RHOB
          Length = 272

 Score =  218 bits (556), Expect = 1e-55,   Method: Composition-based stats.
 Identities = 58/259 (22%), Positives = 103/259 (39%), Gaps = 9/259 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +   Q+TD H+ A    A   V+T    +  +  +   + + D +V +GDL    ++  Y
Sbjct: 1   MIFAQLTDIHIKAGGKFAYNCVDTLSHLRKAVAHLNTFRPQLDFVVISGDLVDLGNADEY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGI----SPAKRVFIGEQWQILLLDSQ 130
           + F + I     P   +PGNHD + AM  A  D G        +     +  +I+ LD+ 
Sbjct: 61  ELFRQEIDQLTMPFYVIPGNHDHRDAMREAFADHGYLSKEGALQFSIEKDGLRIIGLDTT 120

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNA-GELDTV 189
           + G   G     +  WL  +L    ++ TL+ +HH P   G   +D   L  A  +   V
Sbjct: 121 IPGKHDGHFDADKQAWLRAELTAHKDQPTLVFMHHPPFKTGIEHMDDIMLMRADDDFWPV 180

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHC---SNFTLDTIAPGWRTL 246
           +     +  + CGH+H+ +++  NG  +   P++  Q           +     P  R  
Sbjct: 181 VTGQSQILQIACGHVHRAIEVFKNGIPVSICPASGHQVTLDLEPDGEPSFVMDPPAVRIF 240

Query: 247 ELHADGTLTTEVHRLADTR 265
                G L   +  + D  
Sbjct: 241 RWTG-GELINHLSFIGDFG 258


>UniRef50_B3Q6B8 Metallophosphoesterase n=8 Tax=Bradyrhizobiaceae RepID=B3Q6B8_RHOPT
          Length = 284

 Score =  218 bits (555), Expect = 2e-55,   Method: Composition-based stats.
 Identities = 73/271 (26%), Positives = 116/271 (42%), Gaps = 8/271 (2%)

Query: 12  EARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
              + I QI+D H+ A    A   V+T  +    + A+        ++V +GDL    S+
Sbjct: 11  PKPILIAQISDLHIKAPGELAYGKVDTAAALTRCVAALNALAPRPHVVVISGDLVDSPSA 70

Query: 72  AAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGI---SPAKRVFIGEQWQILLLD 128
             Y H    +A  + P V +PGNHD +  M +A          P  +++  +   I+LLD
Sbjct: 71  EEYAHLERLLAPLQIPFVAVPGNHDSRELMRTAFAQPTFPAEGPLNQLYPVDGIDIVLLD 130

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           S V G PHGEL    L+WLE  L+ +  R  LL LHH P   G   +D+ +LRNA E   
Sbjct: 131 SNVHGQPHGELEAGTLQWLEAVLSSSDHRPALLFLHHPPFATGIWHMDRQNLRNAAEFAL 190

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSN---FTLDTIAPGWRT 245
           ++ ++P V+ +  GH+H+     + G      P+               +     P +  
Sbjct: 191 LVERYPWVRLVAAGHVHRATVTGFAGTVATICPAPNHAVALDLGEQLAPSFCVEPPAFHL 250

Query: 246 LELHAD-GTLTTEVHRLADTRFQ-PDTASEG 274
               A+ G L T    +       P   ++G
Sbjct: 251 HAWFAERGELVTHQVPIGAFDGPHPFFGADG 281


>UniRef50_Q0AC05 Metallophosphoesterase n=1 Tax=Alkalilimnicola ehrlichii MLHE-1
           RepID=Q0AC05_ALHEH
          Length = 251

 Score =  217 bits (553), Expect = 4e-55,   Method: Composition-based stats.
 Identities = 91/247 (36%), Positives = 125/247 (50%), Gaps = 4/247 (1%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           R++QITD HL A   + + G++ W S  AVL AI       DL++ +GDL QD       
Sbjct: 5   RLVQITDCHLSAAPGKRVRGMDPWRSLDAVLAAI-GRGPRPDLLLVSGDLTQDLGKPVLA 63

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVP 135
              E +       + LPGNHD   A+      + +          +WQ+LL+D+   G  
Sbjct: 64  RLRERLVPLADRVLALPGNHDDPEALARVFPGSPVDTGATSHSLGEWQLLLMDTSRPGRV 123

Query: 136 HGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPH 195
            GE+   +LE LE  L    E   L   HH PL  G +WLD   L +   L   L + P 
Sbjct: 124 EGEMGVQRLEALEFLL---HEGPALCAGHHPPLACGSAWLDAIGLEDGATLLAWLKRHPQ 180

Query: 196 VKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLT 255
           V+ +L GHIHQ LD      RLL TP+T  QF+P  + F LDT  PG+RT++L  +G LT
Sbjct: 181 VRGMLFGHIHQALDRRQGALRLLGTPATSFQFRPGRARFALDTRLPGYRTVKLWPNGRLT 240

Query: 256 TEVHRLA 262
           + V R+A
Sbjct: 241 SRVSRVA 247


>UniRef50_C8PWU2 Calcineurin phosphoesterase domain protein n=1 Tax=Enhydrobacter
           aerosaccus SK60 RepID=C8PWU2_9GAMM
          Length = 275

 Score =  216 bits (550), Expect = 8e-55,   Method: Composition-based stats.
 Identities = 82/257 (31%), Positives = 132/257 (51%), Gaps = 12/257 (4%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           I++++D HLF   ++ + GVNT +++++VL  +R  + + DL+V TGDL  + +   Y  
Sbjct: 18  IIELSDLHLFDDPNKLMNGVNTADTFESVLSLVRQQRDDVDLLVLTGDLCHEPTPQNYDR 77

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAK----------RVFIGEQWQILL 126
               +     P + +PGNHD    + + L  A                     + W +LL
Sbjct: 78  LFATLDDVNIPFIAIPGNHDVTLELDNHLPFAQRRHLPVKSDSRLQNCYSIATDYWDLLL 137

Query: 127 LDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGEL 186
           LDS   G  HG++ E  L WL ++LA+A  R   +  HH  +    +WLD+++L NA   
Sbjct: 138 LDSSCEGHSHGKIDEQSLLWLAQQLANA-NRPCAIFCHHPMVLIDSTWLDEYTLINADRF 196

Query: 187 DTVLAKF-PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRT 245
             V+  +   +K +  GHIHQE+     G  +   PST +QFKP C ++T+D IAPG R 
Sbjct: 197 WEVVMPYLDRIKAIFVGHIHQEMHKITYGISVFGCPSTSLQFKPLCKDYTIDEIAPGLRW 256

Query: 246 LELHADGTLTTEVHRLA 262
           + L+ +G L T + R  
Sbjct: 257 INLYNNGLLATGIKRTD 273


>UniRef50_C6CXY6 Metallophosphoesterase n=1 Tax=Paenibacillus sp. JDR-2
           RepID=C6CXY6_PAESJ
          Length = 276

 Score =  215 bits (549), Expect = 1e-54,   Method: Composition-based stats.
 Identities = 62/250 (24%), Positives = 95/250 (38%), Gaps = 8/250 (3%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
            +    +TDTH+       L  ++     +AV   I     +   IV +GDL QD     
Sbjct: 3   PILFAHLTDTHVNVPGKTPLFSIDGGAKLRAVFAEIGRLSEKPAFIVISGDLTQDGDVED 62

Query: 74  YQHFAEGIAS----FRAPCVWLPGNHDFQPAMYSAL--QDAGISPAKRVFIGEQWQILLL 127
           Y+   + I         P     GNHD +P        ++         F+ E+ +I++L
Sbjct: 63  YKFLRQLIDEEQAALGIPVYVALGNHDSRPFFREGYLNEEPSEESYHYSFMHEELRIIML 122

Query: 128 DSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELD 187
           ++QV G   G L E QL+WL  +LA      T+++LHH  +      +D H L N   L 
Sbjct: 123 NTQVPGKHDGRLDEAQLDWLSNELASTAPAGTIVVLHHPVVATPSELMDSHLLENPEALA 182

Query: 188 TVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLE 247
            V+A    V  LL GHIH      +      A         P            G+  + 
Sbjct: 183 DVIAG-TDVIGLLSGHIHFNSIGLFRNIPSAAGTGVAFGLDPTSKGSMKFIDNSGYNLV- 240

Query: 248 LHADGTLTTE 257
           L  +G +   
Sbjct: 241 LVKNGQMIVT 250


>UniRef50_Q1QUF7 Metallophosphoesterase n=1 Tax=Chromohalobacter salexigens DSM 3043
           RepID=Q1QUF7_CHRSD
          Length = 244

 Score =  215 bits (549), Expect = 1e-54,   Method: Composition-based stats.
 Identities = 83/254 (32%), Positives = 127/254 (50%), Gaps = 15/254 (5%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +R++QI+D HL A               +AV+   R  + +   ++ TGD++QD+S AAY
Sbjct: 1   MRLVQISDCHLCANPEARSRIGYPLHQLRAVVARARQLRPDI--VLVTGDISQDESPAAY 58

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
           +H  E  ++F  P  W+ GNHD    M        + P        +W++LLLDS+V G 
Sbjct: 59  RHAYEVFSAFECPWFWMTGNHDHPEFMAE------LHPFHDELDLGEWRLLLLDSRVPGQ 112

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
             GEL +  L+ L  +L +  +R TLL +HH PL  G +W+D   L +   L   LA + 
Sbjct: 113 AAGELGQGPLQDLAARLEE-DDRPTLLAMHHPPLEIGSAWMDALGLADREALWQTLAAYG 171

Query: 195 HVKYLLCGHIHQELDLDW----NGRRLLATPSTCVQFKPHCSNFTLDT-IAPGWRTLELH 249
            V+ +LCGHIHQ              +   P+T  QF P  ++F LD    PG+R ++L 
Sbjct: 172 QVRAILCGHIHQAFAARHASSQGEIAVYGCPATADQFLPRQADFALDEASRPGFRVIDLE 231

Query: 250 ADGTLTTEVHRLAD 263
            +  L+T V R+  
Sbjct: 232 GE-RLSTWVERVDP 244


>UniRef50_Q1MS94 Phosphodiesterase n=1 Tax=Lawsonia intracellularis PHE/MN1-00
           RepID=Q1MS94_LAWIP
          Length = 267

 Score =  214 bits (545), Expect = 3e-54,   Method: Composition-based stats.
 Identities = 59/254 (23%), Positives = 109/254 (42%), Gaps = 11/254 (4%)

Query: 12  EARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
           ++ ++ + I+DTH+ AQ        N     Q  ++ I+    +   ++ TGD+  D S 
Sbjct: 2   QSIIKFIHISDTHISAQGCLVYDN-NPRVKLQTCIDEIKRDHLDAAFLILTGDVTNDGSM 60

Query: 72  AAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV---FIGEQWQILLLD 128
             +    E ++    P   + GNHD + ++++A+ +    P   V           ++LD
Sbjct: 61  ECFSFLQEVLSELPMPWYLVMGNHDLKQSLFTAIPEYPRDPNGFVQFTVDTPVGLCIILD 120

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQ--HSLRNAGEL 186
           + +     G L   +L+WL  +L  A  +  LL  HH P   G   +D   HSL+N+ E 
Sbjct: 121 TTIANQSSGILCAARLDWLANELKQAT-KPVLLFFHHPPFSLGIPSMDAIVHSLKNSEEF 179

Query: 187 DTVLAKF-PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPH---CSNFTLDTIAPG 242
             VL  +   ++++  GHIH+ +   WNG      PST  Q   +     +        G
Sbjct: 180 FAVLKPYKDKIRHMFVGHIHRPICGSWNGIPFSCAPSTAHQIALNFQSDKSVLGFKEPSG 239

Query: 243 WRTLELHADGTLTT 256
           +  + ++ D  +  
Sbjct: 240 YSIVLVNNDQLIVH 253


>UniRef50_D1A354 Metallophosphoesterase n=1 Tax=Thermomonospora curvata DSM 43183
           RepID=D1A354_THECD
          Length = 270

 Score =  214 bits (545), Expect = 3e-54,   Method: Composition-based stats.
 Identities = 72/263 (27%), Positives = 114/263 (43%), Gaps = 12/263 (4%)

Query: 17  ILQITDTHLFAQKHEALL-GVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           I Q++D HL A     +        + ++ + ++       D +V TGDLA       Y+
Sbjct: 4   IAQLSDIHLAAGADGRVDDRSGPVRALRSAVSSLLALPQRPDCVVLTGDLADRGLPVEYE 63

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQD--------AGISPAKRVFIGEQWQILLL 127
                ++    P   LPGNHD + A+  A  D           +P +        +++  
Sbjct: 64  RLRALLSPLPMPVFPLPGNHDDRAALREAFADRTAACAAPDPQAPFQYAVQVRGVRLVCC 123

Query: 128 DSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELD 187
           D+ V G  HGEL E +L+WL+  LA AP+  T++  HH P P G  +LD+  LR+A  L 
Sbjct: 124 DTTVPGESHGELDEERLQWLDAALAAAPDVPTVVATHHPPFPIGVRFLDEAGLRDAAALG 183

Query: 188 TVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQF--KPHCSNFTLDTIAPGWRT 245
            VLA+ P V+ ++ GH+H+           +  PST  Q             T  PG  +
Sbjct: 184 AVLARHPQVERVISGHVHRAAVGRIGEITAVTCPSTYRQIYLDTTSPGQAAVTGEPGGFS 243

Query: 246 LELHADGTLTTEVHRLADTRFQP 268
           L L  +G      H +    ++P
Sbjct: 244 LHLVGEGRPGVS-HFVPTGDYRP 265


>UniRef50_Q1LDS0 Metallophosphoesterase n=10 Tax=Proteobacteria RepID=Q1LDS0_RALME
          Length = 290

 Score =  213 bits (544), Expect = 4e-54,   Method: Composition-based stats.
 Identities = 66/276 (23%), Positives = 114/276 (41%), Gaps = 12/276 (4%)

Query: 11  GEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQS 70
             A   + Q+TD H+ A    +   V+T  + +  ++ +     + D+++ TGDL    S
Sbjct: 11  NAAPYLVAQLTDLHIKAGGKLSYRRVDTAGALRTAIDTLLAAPQQPDIVIVTGDLVDFGS 70

Query: 71  SAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDA--------GISPAKRVFIGEQW 122
            + Y+   + +     P   LPGNHD +P++ +   D         G +P          
Sbjct: 71  ESEYRFLRDLLQPLPMPVRLLPGNHDHRPSLRAVFADHDYLFANGDGDAPVHYAIDAGPL 130

Query: 123 QILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRN 182
           +++  D  V G P G   +  L WL+  LA AP++ TL++LHH P   G   +D   L N
Sbjct: 131 RLVGFDCTVPGKPGGRAEDAGLAWLDATLAAAPKQPTLVMLHHPPFHTGIGHMDDQGLEN 190

Query: 183 AGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSN---FTLDTI 239
           A   + ++A+ P V+ ++CGH+H+ +   + G   +  P    Q                
Sbjct: 191 APAFEAIIARHPQVERVVCGHLHRHITRRFGGTIAMTAPGPAHQVALDLDPQAASRFRME 250

Query: 240 APGWRTLELHA-DGTLTTEVHRLADTRFQPDTASEG 274
            PG+     H   G +T            P   + G
Sbjct: 251 PPGYLLHWWHPAHGMVTHLAASGDYGALHPFFDANG 286


>UniRef50_Q1Q887 Metallophosphoesterase n=2 Tax=Psychrobacter RepID=Q1Q887_PSYCK
          Length = 279

 Score =  213 bits (543), Expect = 5e-54,   Method: Composition-based stats.
 Identities = 83/279 (29%), Positives = 129/279 (46%), Gaps = 21/279 (7%)

Query: 4   LLTLPLAG----EARVRILQITDTHLFAQ-----KHEALLGVNTWESYQAVLEAIRPHQH 54
           + + P++     + +V +LQITD HL +         +        S++A+++     + 
Sbjct: 1   MPSYPVSAVSTPDGQVNVLQITDLHLSSHVPASADETSSEVAVCQYSFEAIIKQALSKEI 60

Query: 55  EFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQD------- 107
             DLI+ TGDL      A Y H    +     P   + GNHD    M   L         
Sbjct: 61  RCDLIIVTGDLVNKVEPAIYDHIFTVLKETGIPFACIAGNHDVTDEMGEDLPFYQRTLIA 120

Query: 108 ---AGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLH 164
                   ++ +   E WQ+LLLDS + G   GE++   ++W+  +LA    +  L+ LH
Sbjct: 121 RACDPRLLSRHLIESEHWQLLLLDSSITGKVEGEITATDIDWVREQLASCA-KPALIALH 179

Query: 165 HHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTC 224
           HH LP    W+D H   NA E    +  F ++  ++ GH HQE    + G  + +TPSTC
Sbjct: 180 HHVLPVDSEWIDSHMAENAEEFWQHITPFENLSVIINGHTHQEQTRHYQGVTVYSTPSTC 239

Query: 225 VQFKPHCSNFTLD-TIAPGWRTLELHADGTLTTEVHRLA 262
            QFKP   NF  D  + PG+R L+L  +G + + V RL 
Sbjct: 240 YQFKPFEDNFAYDKNMRPGYRWLQLANNGKVASWVERLD 278


>UniRef50_C1CX57 Putative Metallophosphoesterase; putative cAMP phosphodiesterase
           n=1 Tax=Deinococcus deserti VCD115 RepID=C1CX57_DEIDV
          Length = 267

 Score =  213 bits (543), Expect = 5e-54,   Method: Composition-based stats.
 Identities = 59/226 (26%), Positives = 103/226 (45%), Gaps = 9/226 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + I Q++D H+ A+  +         + +  +  +       DL++ TGD  +    A Y
Sbjct: 1   MLIAQLSDPHVMAEPDDQ-----AAHALRRAVSHLLELPVLPDLVLITGDCTEHGEVAEY 55

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGI----SPAKRVFIGEQWQILLLDSQ 130
           + F   I     P   +PGNHD + AM SAL   G        + V      +++ LD+ 
Sbjct: 56  ETFRTLIQPLPMPVYVVPGNHDQRAAMLSALGRPGTLGLEGFMQYVVEAGPLRLIGLDTH 115

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
           + G   GEL   +L+WLE +L +AP R  ++ +HH P  +  + +D   LR+    + +L
Sbjct: 116 LPGQDAGELCAARLDWLEDRLTEAPGRPCVIFMHHPPARSSLNVMDGIGLRDPQAFEALL 175

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTL 236
           A+  +V+ +L GH+H  +     G  L+  P T   + P   +   
Sbjct: 176 ARHSNVERVLTGHLHMAMTRRCGGTLLMTAPGTQHTWLPDLGHPER 221


>UniRef50_A1ZTZ2 Metallophosphoesterase n=1 Tax=Microscilla marina ATCC 23134
           RepID=A1ZTZ2_9SPHI
          Length = 251

 Score =  212 bits (540), Expect = 1e-53,   Method: Composition-based stats.
 Identities = 73/251 (29%), Positives = 118/251 (47%), Gaps = 5/251 (1%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
            +R   ++D HL+  K       + ++S+  V++ +   +   D I+ TGD+A  Q   +
Sbjct: 3   TLRFAHLSDLHLYKYKDFMYHEHHPYQSFCNVVD-LLKQEDTLDFILITGDIAAKQEKES 61

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQ--V 131
           Y H  E +A    P  WLPGNHD    M        +     VF  +  + +LLDS    
Sbjct: 62  YFHVDELLAPLGTPYYWLPGNHDSAVLMKRIAPKVQVQNTN-VFETKGTRFILLDSTDRQ 120

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
                G L + +L +LE+ LA+A    T++ LHH  L    SW +   + N  +   ++ 
Sbjct: 121 EKAVAGFLPDDELRFLEKSLAEATNTSTIIALHHQLLATPGSWTNNLGVTNKNDFYKIID 180

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHA- 250
             P V+ ++CGHIH        G +  + P+T  QF P+   F LD +APG++ L +H  
Sbjct: 181 ACPQVQAVICGHIHHAHAWQRKGVQYFSAPATSYQFNPYAPEFALDELAPGYQVLSIHPK 240

Query: 251 DGTLTTEVHRL 261
              +  EV R+
Sbjct: 241 TRRVHCEVKRI 251


>UniRef50_A7IH99 Metallophosphoesterase n=2 Tax=Xanthobacteraceae RepID=A7IH99_XANP2
          Length = 276

 Score =  211 bits (539), Expect = 2e-53,   Method: Composition-based stats.
 Identities = 71/271 (26%), Positives = 110/271 (40%), Gaps = 11/271 (4%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + I Q+TDTH+      A   V+T    +A +  I       D+++ TGDL      A Y
Sbjct: 1   MLIAQLTDTHIRRPGTLAYGVVDTALYLEAAVAHILALAPRPDVVIVTGDLTDFDDPAEY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDA----GISPAKRVFIGEQWQILLLDSQ 130
             F    A+   P + +PGNHD    + +A  +            V      ++++LDS 
Sbjct: 61  ARFRALTAALPMPLLPIPGNHDSSAGLLAAFPEIAARCDGGRVNYVVEDFPLRLVMLDST 120

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
           V+G PHG+L E  L +L+R L   P R   +  HH P   G   +D  +L +A  L+ V 
Sbjct: 121 VYGCPHGQLGEEGLAFLDRALGATPGRPAFVCAHHPPFLTGIRHMDVQNLSDAAGLEEVF 180

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQF--KPHCSNFTLDTIAPGWRTLEL 248
             +P V    CGH+H+ +   + G      P+                  + P   +L L
Sbjct: 181 GHWPQVLGFTCGHVHRAVTTTFAGIAATIGPAPAHAVSLALDPQAPPTFHMEPPSLSLHL 240

Query: 249 HADGTLTTEVHRLADTR-----FQPDTASEG 274
             DG + T    +         F PD  + G
Sbjct: 241 FTDGRVVTHRSFIGAYDGPHPFFGPDGKAIG 271


>UniRef50_A6D2K7 Ser/Thr protein phosphatase family protein n=1 Tax=Vibrio shilonii
           AK1 RepID=A6D2K7_9VIBR
          Length = 271

 Score =  211 bits (538), Expect = 2e-53,   Method: Composition-based stats.
 Identities = 70/271 (25%), Positives = 114/271 (42%), Gaps = 15/271 (5%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + I Q+TD H+      A   V+T    Q  ++ I       D +V TGDL    +   Y
Sbjct: 1   MLIAQLTDLHIKQDGKPAYRKVDTLRCLQNAVQHINHLNPRPDYVVITGDLGDFGTEQEY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQD----AGISPAKRVFIGEQWQILLLDSQ 130
           Q   + +   + P   +PGNHD +  +   LQ             V   ++  +L LDS 
Sbjct: 61  QIIRQELEKLQLPLRVVPGNHDHRDNLRVGLQQLVDFDHPEFCNFVVEQDEQVLLGLDSS 120

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
           V G P+G LS   LEWL+ +LA    +  L+ LHH P+  G   +D  +L NA  L  VL
Sbjct: 121 VIGKPYGFLSSQTLEWLQSQLARLSNKSVLIFLHHPPMHVGLGHMDVQNLTNADSLYEVL 180

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGW----RTL 246
           ++F +V+ L  GH+H+ +   W    +   PS                    +    R +
Sbjct: 181 SQFDNVRGLCAGHLHRPITATWRSIPVWVGPSHSHSVTLDLDP----NAPSSFSLEPRAI 236

Query: 247 EL--HADGTLTTEVHRLADTRFQ-PDTASEG 274
           +L    + ++ + +  + D+    P    +G
Sbjct: 237 QLLKFENDSVVSHISYIEDSDGPHPFFDEQG 267


>UniRef50_A3RQT5 Icc protein n=4 Tax=Ralstonia solanacearum RepID=A3RQT5_RALSO
          Length = 263

 Score =  210 bits (536), Expect = 3e-53,   Method: Composition-based stats.
 Identities = 61/246 (24%), Positives = 111/246 (45%), Gaps = 4/246 (1%)

Query: 18  LQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHF 77
            QITD HL A +   L+G  T+      ++AI  H    D+   TGD++QD+S  +Y+  
Sbjct: 20  AQITDLHLLADRESELMGYCTYSMLSDTVDAILEHDIRPDVCFLTGDISQDESVESYELA 79

Query: 78  AEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHG 137
              +     P  W+PGNHD +    +    +         +   W  + LD+   G   G
Sbjct: 80  RSELERLGIPVFWIPGNHDERDGAEAVFGASESIRRLTKLVTADWDFIYLDTCRQGAGEG 139

Query: 138 ELSEFQLEWLERKLADA--PERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPH 195
            L++   E    ++  +    ++  +++HHHP+P     LD + L +   L  +L +   
Sbjct: 140 YLNDQDFERFVSQVEASTGGGKNIAVVMHHHPVPTQTPLLDGYMLLDNERLLKMLDEHQQ 199

Query: 196 VKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLT 255
           VK ++CGH+H +  + +  + +   P+TC Q++   S    +    G+R  E    G   
Sbjct: 200 VKLVICGHVHGDYRIRYGNQMIEMCPATCFQWEKGTSAMKTENWR-GFRVFEFSPSG-YR 257

Query: 256 TEVHRL 261
           + + R+
Sbjct: 258 SALIRV 263


>UniRef50_Q2BR54 Metallophosphoesterase n=1 Tax=Neptuniibacter caesariensis
           RepID=Q2BR54_9GAMM
          Length = 256

 Score =  210 bits (536), Expect = 4e-53,   Method: Composition-based stats.
 Identities = 82/262 (31%), Positives = 129/262 (49%), Gaps = 13/262 (4%)

Query: 9   LAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQD 68
           +A  A + +LQ++D HL  +    L GVN  + +Q VL  I       D ++ TGDL   
Sbjct: 1   MADTAPILLLQVSDMHLQQEPDMLLKGVNVEQRFQQVLVEIESQS--ADALLLTGDLTHH 58

Query: 69  QSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLD 128
               AY+     +     P  W+PGNHD    M       G   A+RV     W+++ LD
Sbjct: 59  A-PRAYERLVSYVDCLPYPAYWIPGNHDLPEEMARF---TGTELAQRVKTFGGWKLIFLD 114

Query: 129 S--QVFGVPHGELSEFQLEWLERKLAD-APERHTLLLLHHHPLPAGCSWLDQHSLRNAGE 185
           S     G   G LSE +L +L+ +L+  A ++H LL+LHHHP+P    W D+  L NA +
Sbjct: 115 SSSNPDGKGSGSLSETELSFLKAELSQTAADQHVLLVLHHHPVPVQSRWQDEICLANAEQ 174

Query: 186 LDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA----P 241
              ++  +P VK ++ GH+HQ  +L     +L + P+T  QFK    +  ++       P
Sbjct: 175 FWQIVDLYPQVKGVIFGHVHQSWELQRGDIQLFSVPATAAQFKAQTDSSEVENDPKLAGP 234

Query: 242 GWRTLELHADGTLTTEVHRLAD 263
            +   +LH+ G ++ +V RL  
Sbjct: 235 AYGRYQLHSCGKISQQVIRLPA 256


>UniRef50_Q4ZTD8 Metallophosphoesterase n=4 Tax=Pseudomonas syringae group
           RepID=Q4ZTD8_PSEU2
          Length = 265

 Score =  210 bits (536), Expect = 4e-53,   Method: Composition-based stats.
 Identities = 62/265 (23%), Positives = 110/265 (41%), Gaps = 8/265 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + I  I+DTH+  +       V++     A ++ I       DLI+ +GDL  +     Y
Sbjct: 1   MLIAHISDTHVRPRGQLYQGVVDSNAMLAAAVDTINTLDPAPDLILFSGDLVDEGRPEEY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGIS--PAKRVFIGEQ---WQILLLDS 129
               E +   R   + +PGNHD +  +  A  +           F+       +I+ LD 
Sbjct: 61  AMARELLQPLRQKLLMIPGNHDHRQNLRDAFAEHDYFINDQDCSFVYSGSAPVRIIGLDI 120

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
            V    HG++++  + WL+  LA  P++ TL+++H  P  +G  ++D +       L  V
Sbjct: 121 SVPEQHHGDMTDTAIRWLDSTLALEPDKPTLIMMHQPPFSSGIPYIDAYRCERGERLAEV 180

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDT---IAPGWRTL 246
           ++++P ++ ++CGHIH+ + L + G  +   PST             D      P     
Sbjct: 181 VSRYPAIERIVCGHIHRFMQLRFGGTLMCTAPSTTTAIALRLHPEAADASYVEPPALLLH 240

Query: 247 ELHADGTLTTEVHRLADTRFQPDTA 271
              AD  L T    +       D A
Sbjct: 241 HWKADTGLITHWVPIGRFEGPFDFA 265


>UniRef50_B0UF90 Metallophosphoesterase n=2 Tax=Methylobacterium RepID=B0UF90_METS4
          Length = 275

 Score =  210 bits (535), Expect = 4e-53,   Method: Composition-based stats.
 Identities = 66/273 (24%), Positives = 110/273 (40%), Gaps = 13/273 (4%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + I QITD HL  +   A     T    +  ++A+   Q   D+++ TGDL        Y
Sbjct: 1   MLIAQITDLHLRPRGRPAYRVAETNMLVERAVDALASLQPRPDVVLVTGDLTDCGLPEEY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGI-----SPAKRVFIGEQWQILLLDS 129
                 +     P   +PGNHD + A+ +AL  A +        + V      +++ LD+
Sbjct: 61  ALLRGLLGRLPLPVFVVPGNHDRREALRAALPAAWLPGAMEEFVQYVVDDWPVRLIGLDT 120

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAG-ELDT 188
            V G  HG L   +L +LE  LA   +R TL+ LHH P   G   +D+  L +    L  
Sbjct: 121 LVAGASHGALCARRLAFLEEALAAGGDRPTLVFLHHPPFACGMEGMDRIRLLDGEPRLRA 180

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFT---LDTIAPGWRT 245
           ++   P+V+ +LCGH H+ + + + G      P    Q     +      L    P ++ 
Sbjct: 181 LIEAHPNVERILCGHHHRPIQVRYAGTIAQVAPGVAHQVALDLNPGRESGLVLEPPAFQL 240

Query: 246 LELHADGTLTTEVHRLA----DTRFQPDTASEG 274
                +  + + +  +        F  D    G
Sbjct: 241 HRYAPETGIVSHMVYVERYPGPFPFVLDPDYPG 273


>UniRef50_A8U260 Ser/Thr protein phosphatase family protein n=1 Tax=alpha
           proteobacterium BAL199 RepID=A8U260_9PROT
          Length = 268

 Score =  209 bits (532), Expect = 1e-52,   Method: Composition-based stats.
 Identities = 58/265 (21%), Positives = 105/265 (39%), Gaps = 9/265 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +  +QITD H+    +     V+T      ++  +         ++ TGDL  + S A Y
Sbjct: 1   MLFVQITDLHVRESGNPLAGRVDTAGFLDRMVTRLNALNPRPGAVLITGDLIDNGSEAEY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSAL-----QDAGISPAKRVFIGEQWQILLLDS 129
           +   + +A+   P     GNHD + A  ++       DAG +  +     +  ++L+LD+
Sbjct: 61  RLLRQRLAALDMPVYLALGNHDGREAFRASFTDLDYWDAGTAFVQYAVDLDGVRLLVLDT 120

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHS-LRNAGELDT 188
              G P G L   +L WL  +LA+     T++ +HH P+P G   +D    L  A     
Sbjct: 121 HEPGKPSGVLCLERLNWLSDRLAEDRSTPTVVAMHHPPVPVGMPNMDPSRLLAGAERFKE 180

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFK---PHCSNFTLDTIAPGWRT 245
           ++A  P+V+ +L GH+H+ +   + G  L   P    Q           +     P  + 
Sbjct: 181 LIAGAPNVERILAGHLHRSVTARFAGTVLDVMPGVAHQIHLDLMGERPLSFAFEPPMLQL 240

Query: 246 LELHADGTLTTEVHRLADTRFQPDT 270
             +     L +       +      
Sbjct: 241 HAMVPGAGLVSHKVYAEPSDGPYPF 265


>UniRef50_D1U8L8 Metallophosphoesterase n=1 Tax=Desulfovibrio aespoeensis Aspo-2
           RepID=D1U8L8_9DELT
          Length = 282

 Score =  209 bits (532), Expect = 1e-52,   Method: Composition-based stats.
 Identities = 64/274 (23%), Positives = 105/274 (38%), Gaps = 15/274 (5%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWE---SYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
           + I  I+D H+     +    V+T      + A L +I       D ++ TGD+      
Sbjct: 1   MLIAHISDLHIRPHGEKLYDFVDTNALISRHVATLNSIAKTTDSPDAVLITGDIVNCGQK 60

Query: 72  AAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQD----------AGISPAKRVFIGEQ 121
             Y      +     P   +PGNHD    +  AL D           G    +       
Sbjct: 61  QEYAMARRILGQLTMPLYIIPGNHDNNANLLEALTDICPPLENVGKTGEHTIRYTIEEFP 120

Query: 122 WQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLR 181
            + ++LDS + G  HGE+   Q+ WLE++L     R T + +HHHPLP+G + +D     
Sbjct: 121 VRFIMLDSSIGGELHGEIGREQMAWLEKELQKGTGRETAVCMHHHPLPSGNAHMDAIKCH 180

Query: 182 NAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTI-- 239
           +   L  +L+++P+V  L+CGH H+ +  +     +   P    Q   H ++        
Sbjct: 181 DGEALIEMLSRYPNVTRLICGHTHRSIFQNVGRILICTVPGAAHQVPFHSTDLDGSYTLE 240

Query: 240 APGWRTLELHADGTLTTEVHRLADTRFQPDTASE 273
            P         +  L T    LA         S 
Sbjct: 241 PPALYFHRHTPETGLVTYSQSLAPFDGPYPFDSA 274


>UniRef50_Q89MQ1 Bll4141 protein n=1 Tax=Bradyrhizobium japonicum RepID=Q89MQ1_BRAJA
          Length = 283

 Score =  208 bits (529), Expect = 2e-52,   Method: Composition-based stats.
 Identities = 66/273 (24%), Positives = 111/273 (40%), Gaps = 13/273 (4%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
             + + ITDTHL A     L G++      A +  I  HQ +    V TGDL       +
Sbjct: 2   PFKFIHITDTHL-ANPGLKLYGLDPRARLDAAIADINKHQSDAAFAVVTGDLTHWGEPES 60

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV---FIGEQWQILLLDSQ 130
           Y +FA+ +A+ + P + + GNHD + A    L+ A       V    I E    + LD+ 
Sbjct: 61  YANFADAMAALKIPYIAMVGNHDKRVACLDGLKAAPRDSNGFVQGTRITEHGLFVFLDTL 120

Query: 131 VFGVPHGELSEFQLEWLERKLADAPER-HTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
                 GE+   +L WL   LA AP     ++ +HH P P G   +D+ SL+ + E   V
Sbjct: 121 DETSHAGEMCAKRLGWLASTLAAAPADMPFVVFMHHPPFPVGVHAMDEISLKQSPEFAEV 180

Query: 190 LAKF-PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFK----PHCSNFTLDTIAPGWR 244
           +A +   +++L  GH+H+ +   +          T  Q         +        P + 
Sbjct: 181 IAPYRSRIRHLFFGHVHRPIFGSYGKIPFSTLRGTNHQVWFELDAAAAEHLASHEPPAYG 240

Query: 245 TLELHADGTLTTEVHRLAD---TRFQPDTASEG 274
            + +  +  +      L +     F+P    +G
Sbjct: 241 VVLIDGENLVVHSHDFLDESLRFPFEPPAGVDG 273


>UniRef50_A8ZM80 Phosphodiesterase, putative n=1 Tax=Acaryochloris marina MBIC11017
           RepID=A8ZM80_ACAM1
          Length = 259

 Score =  207 bits (528), Expect = 2e-52,   Method: Composition-based stats.
 Identities = 94/258 (36%), Positives = 126/258 (48%), Gaps = 13/258 (5%)

Query: 13  ARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA 72
           A + + QI+DTHL A     L G N W+S QAVL+ +   Q +   I+ TGDLA   S  
Sbjct: 3   APITLAQISDTHLLADTTALLRGTNPWQSLQAVLQQVNRDQLDG--ILLTGDLADQGSVV 60

Query: 73  AYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVF 132
           AYQH    I   + P  WLPGNHD   AM+  LQ   +    +      W ++ L+S + 
Sbjct: 61  AYQHLMRAILPLKMPAYWLPGNHDQVEAMHRELQSPQL-YGPQAIHLGSWLLISLNSVLP 119

Query: 133 GV--PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
                 G LS   L+ L+  L   P + T++ LHHHP+  G  WLDQ  ++NA  L T+L
Sbjct: 120 SAQFGEGYLSVSALQQLQSVLTQHPHKPTVIALHHHPVAIGIDWLDQMQVQNADALLTLL 179

Query: 191 AKFPHVKYLLCGHIHQELDLDW------NGRRLLATPSTCVQFKPHCSNFTLDTIAPGWR 244
             FP VK +L GHIH +           +       PSTC+Q  P        T  PG+R
Sbjct: 180 ESFPQVKVVLFGHIHLDFQYQHVFSQRPSPIYFYGCPSTCLQVNPPVPTD--HTHLPGFR 237

Query: 245 TLELHADGTLTTEVHRLA 262
            L L  +GT  T V R+ 
Sbjct: 238 LLSLDPNGTHRTWVQRVE 255


>UniRef50_B9QUB7 Ser/Thr protein phosphatase family protein n=1 Tax=Labrenzia
           alexandrii DFL-11 RepID=B9QUB7_9RHOB
          Length = 278

 Score =  207 bits (528), Expect = 2e-52,   Method: Composition-based stats.
 Identities = 62/258 (24%), Positives = 100/258 (38%), Gaps = 10/258 (3%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           I  ITD HL  +        +T    +  + A+       D +V TGDL        Y  
Sbjct: 4   IAHITDLHLRPRGLACYRVSDTNMLAERAILALNGLTPRPDAVVLTGDLTDKSDPREYAL 63

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGI------SPAKRVFIGEQWQILLLDSQ 130
             + ++    P   +PGNHD    M   +                       +++ LD+ 
Sbjct: 64  ARQILSRLAMPVFMIPGNHDGSADMRREMSGFPGMDGDVDGKLCYTAEIGDVRLIALDTN 123

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
           + G P+GEL   QL WL  +L+D   R TL+ LHH P  +G   +D   L +A  L  V+
Sbjct: 124 IPGKPNGELGTPQLNWLSDRLSD-DNRPTLIALHHPPALSGIQHMDAIGLNDANALAEVI 182

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSN---FTLDTIAPGWRTLE 247
               H++ LLCGH+H+ +  ++ G+ +   PST  Q     +       +   P +    
Sbjct: 183 GPHKHIQRLLCGHLHRPIIAEFAGKIMTLAPSTGHQVVLDLTEDGPPMFNFEPPAYFLHH 242

Query: 248 LHADGTLTTEVHRLADTR 265
                   T +  +    
Sbjct: 243 HTLQAGTVTHMAYVEAYP 260


>UniRef50_A0NY27 Metallophosphoesterase n=2 Tax=Rhodobacteraceae RepID=A0NY27_9RHOB
          Length = 270

 Score =  205 bits (523), Expect = 1e-51,   Method: Composition-based stats.
 Identities = 64/264 (24%), Positives = 100/264 (37%), Gaps = 9/264 (3%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEF---DLIVATGDLAQDQSSA 72
           +I+QI+DTH+  +   A   V+T  +    +  I          DL++ TGDL +  +  
Sbjct: 3   KIIQISDTHIVPEGTLAYDQVDTAAALAETVATINRLLPRIGPVDLVIVTGDLTEHGTPE 62

Query: 73  AYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGI----SPAKRVFIGEQWQILLLD 128
            Y  F   +A    P   LPGNHD +  M  +           P       E + ++ LD
Sbjct: 63  EYDRFKNLMADLELPYRVLPGNHDRREPMRESFSGENWMPRTGPVNWQIDLEDFAVVGLD 122

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           S      HG L    L +L   L D  ++  L+  HH P   G   +D  +L +A  L +
Sbjct: 123 SLTENAAHGTLEAATLSFLTDALTDIGDKPALVGFHHPPFAVGIEAMDAQNLHDANSLGS 182

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLD--TIAPGWRTL 246
            L+       L+CGH+H+ +   ++G      P T             +  T  PG   L
Sbjct: 183 ALSLHSGQVRLVCGHLHRSIAGLFSGSLCQVCPGTSHAVTLDQRANAGNSLTKEPGGMLL 242

Query: 247 ELHADGTLTTEVHRLADTRFQPDT 270
               DG   T +  +         
Sbjct: 243 HEWRDGGFLTHLIPVGTYPGPYPF 266


>UniRef50_Q2J948 Metallophosphoesterase n=5 Tax=Actinomycetales RepID=Q2J948_FRASC
          Length = 287

 Score =  203 bits (517), Expect = 5e-51,   Method: Composition-based stats.
 Identities = 67/262 (25%), Positives = 113/262 (43%), Gaps = 8/262 (3%)

Query: 4   LLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATG 63
           +L  P A      ++QI+DTH+  +       V+T+ + + VL+ I     +   ++ TG
Sbjct: 3   ILLDPTAHTPTHILIQISDTHIVREGELMHGKVDTYAALRTVLDQIEASTLKIGALLLTG 62

Query: 64  DLAQDQSSAAYQHFAEGI----ASFRAPCVWLPGNHDFQPAMYSAL--QDAGISPAKRVF 117
           DLA      AYQ   + +    A    P ++  GNHD +      L   +        V 
Sbjct: 63  DLADRGDLLAYQRLRDLVEPAAARLGTPVLYGVGNHDSRGPFREGLLGAEPTAEAHDYVH 122

Query: 118 IGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQ 177
                +I++LD+   G   G LS  QL WL  +LA A    T+L LHH P+P+  + ++ 
Sbjct: 123 WVGDLRIIMLDTTEPGEHSGFLSTAQLRWLADELATAAPDGTILALHHPPVPSPLAMVNS 182

Query: 178 HSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLD 237
             L     L  VLA    VK +L GH H       +G  +    +T  + +       + 
Sbjct: 183 LLLAEPQNLADVLAG-SDVKIVLAGHAHHASAGVLSGVPVWVAGATAYRIRTLGPADRIT 241

Query: 238 TIAPG-WRTLELHADGTLTTEV 258
            +  G +  ++++ +G + T V
Sbjct: 242 GLVGGEYTRIDVYPEGAVATAV 263


>UniRef50_B8J1S2 Metallophosphoesterase n=1 Tax=Desulfovibrio desulfuricans subsp.
           desulfuricans str. ATCC 27774 RepID=B8J1S2_DESDA
          Length = 276

 Score =  203 bits (517), Expect = 6e-51,   Method: Composition-based stats.
 Identities = 71/259 (27%), Positives = 111/259 (42%), Gaps = 12/259 (4%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + ILQ++DTHL      +   V+T     A    ++    + D+IV +GDLA      AY
Sbjct: 1   MHILQLSDTHLRGDNSLSFRVVDTRRCLDAATAHLKTMAQKPDIIVLSGDLADSGDLNAY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAK------RVFIGEQWQILLLD 128
               + ++    P   LPGNHD +  M   LQ    +  +           ++ +++++D
Sbjct: 61  HILYDALSPLGIPVYALPGNHDRRDRMRDVLQGWCPAAPEVSPHICYTVEMDELRLVMVD 120

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           S   G   G L      WL R LA  P+  TL+ +HH P   G   +D+    N G L  
Sbjct: 121 SMHPGSHSGHLFPAVEGWLARTLAQRPDVQTLVFMHHPPFMTGMGAMDE-PFENQGALAA 179

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDT---IAPGWRT 245
           +    P ++    GH+H+ +   W GR  +  PS  +Q     S    DT    APG+  
Sbjct: 180 IAGDNPQIRLCF-GHMHRPIITQWQGRLCMTAPSAAMQIDLDLSPEGGDTFRMEAPGY-L 237

Query: 246 LELHADGTLTTEVHRLADT 264
           L  +  G L T V ++   
Sbjct: 238 LHHYEHGILNTHVCQIPSD 256


>UniRef50_Q162P5 Ser/Thr protein phosphatase family protein, putative n=7
           Tax=Rhodobacterales RepID=Q162P5_ROSDO
          Length = 267

 Score =  202 bits (515), Expect = 9e-51,   Method: Composition-based stats.
 Identities = 71/266 (26%), Positives = 112/266 (42%), Gaps = 16/266 (6%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEF---DLIVATGDLAQDQSSA 72
            IL ITDTH+  +       ++T ++ + ++  I   + +    D ++ +GDL+ D S+ 
Sbjct: 3   TILHITDTHIVPEGALVSGRLDTADALERLVARINSIRDQIGAVDAVLVSGDLSDDGSAE 62

Query: 73  AYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQD--AGISPAKRVFIGEQWQILLLDSQ 130
           +Y+ F   +A    P   +PGNHD +  + +A  +  A   P   V       ++ LD+ 
Sbjct: 63  SYKRFKRLVAPLGLPIHVIPGNHDGRATLRAAFAEQFAPTGPLNWVRSIGDLHLIGLDTL 122

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
           V G   G L+   L +L   L+ A     LL LHH P   G  ++D   L N   L  ++
Sbjct: 123 VEGQGGGRLAPESLSFLSDALSQAEGAPVLLALHHQPFLCGIGFMDAIGLSNKNALSEIV 182

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWR------ 244
           A +     LLCGHIH  +  D  G   ++ PS C  F   C          G+       
Sbjct: 183 AGYQGPLRLLCGHIHSTMISDVGGHIAISCPSPCSSFAFDCRP----DAPRGYMHQEDGC 238

Query: 245 TLELHADGTLTTEVHRLAD-TRFQPD 269
            L     G  T  +  +A    F  D
Sbjct: 239 LLHRWDGGFQTIRIGPVAGAGPFPFD 264


>UniRef50_A4EV76 3',5'-cyclic-nucleotide phosphodiesterase, cpdA n=1 Tax=Roseobacter
           sp. SK209-2-6 RepID=A4EV76_9RHOB
          Length = 266

 Score =  202 bits (514), Expect = 1e-50,   Method: Composition-based stats.
 Identities = 59/254 (23%), Positives = 108/254 (42%), Gaps = 10/254 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++++ ++D H  A  +  +LG +     +A +  I     E    + TGDL +      Y
Sbjct: 5   LKLIWLSDLHFLATGN--VLGHDPRLRLEAAISHISACYPEAAACIITGDLVESAEPEHY 62

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQ---DAGISPAKRVFIGEQWQILLLDSQV 131
           +     +++     + L GNHD +  +         A     +      +  ++ LD+ V
Sbjct: 63  EALQTQLSNLPGQLLPLTGNHDDRDLLRQVFSLPNVAMAEFVQYRVDFPRLSVVALDTLV 122

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
            G  +G L   +LEWL++ L D  +   LL +HH P+  G   LD+ +LRN  EL  +L 
Sbjct: 123 SGQGYGFLCAQRLEWLQQTLDDCRDGPLLLAMHHPPMKLGLPILDEDNLRNGQELLELLK 182

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLD-----TIAPGWRTL 246
              ++++LL GH+H+ +     G     + S   Q  P    +  +       AP +  +
Sbjct: 183 GRNNIQHLLLGHVHRPVAGLTAGIPFKTSKSILYQAPPAVPAWDWESFSPAPEAPAYTVI 242

Query: 247 ELHADGTLTTEVHR 260
           E+   G    E+  
Sbjct: 243 EVTETGVTLQEMCF 256


>UniRef50_C6D6T3 Metallophosphoesterase n=1 Tax=Paenibacillus sp. JDR-2
           RepID=C6D6T3_PAESJ
          Length = 273

 Score =  201 bits (512), Expect = 2e-50,   Method: Composition-based stats.
 Identities = 58/254 (22%), Positives = 98/254 (38%), Gaps = 9/254 (3%)

Query: 13  ARVRILQITDTHLFAQK-HEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
            +++ + +TDTH+ A          N  +  + V E I+        +V TGDL  + + 
Sbjct: 2   EKLKFVHLTDTHMNAPGVDNPFAKFNLADKVKRVFEHIKTASVSPAFVVITGDLTHEGNV 61

Query: 72  AAYQHFAEGIAS----FRAPCVWLPGNHDFQPAMYSAL--QDAGISPAKRVFIGEQWQIL 125
             Y++    +         P   + GNHD +         ++            +  +++
Sbjct: 62  QDYEYIRTIVDEGSALLGVPVHVVLGNHDHRAPFREGFLKEEPSEQAYYYSHTIQGVRLI 121

Query: 126 LLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGE 185
            L+SQV G  HGE+   QL WLE  L+   E  T++ LHH  L       D H L N  +
Sbjct: 122 GLNSQVKGQHHGEIDAEQLAWLEDTLSTPAENGTIVALHHPMLNINGMPAD-HVLANRDQ 180

Query: 186 LDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRT 245
           L  VL     V  ++ GH+H      + G   +A   T    +    N        G+  
Sbjct: 181 LGNVLEG-TDVIGVVAGHVHTNNVGTYKGICHVAATGTAFGGEAAEDNHFKMVDFCGYNI 239

Query: 246 LELHADGTLTTEVH 259
           + ++ +G     V 
Sbjct: 240 VSVYEEGVTVQTVV 253


>UniRef50_Q1GM28 Metallophosphoesterase n=3 Tax=Rhodobacteraceae RepID=Q1GM28_SILST
          Length = 270

 Score =  201 bits (511), Expect = 3e-50,   Method: Composition-based stats.
 Identities = 60/262 (22%), Positives = 117/262 (44%), Gaps = 15/262 (5%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQH---EFDLIVATGDLAQDQSSAA 73
            +Q+TDTH+ ++   A    +T  +    ++ I          D +V TGDL    S+  
Sbjct: 4   FIQLTDTHIVSEGSLAYGRSDTATALARAVDTINSRLPVLDPVDCVVVTGDLTDHGSAEE 63

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGI----SPAKRVFIGEQWQILLLDS 129
           Y H  + +A    P   +PGNHD + AM +A           P +       + ++ LD+
Sbjct: 64  YAHLRQLLAPLNVPVRAIPGNHDTREAMRAAFATEDWMPASGPIQWHHDFGPFAMVGLDT 123

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
            V G P+G + E  L +L R L   P++  ++  HH  +P+G + +D+++LRN   +  +
Sbjct: 124 LVEGAPYGMVCEAGLGFLARSLKTTPDKPLVVATHHPWIPSGMADMDRNNLRNGPAMLDL 183

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDT--IAPG----W 243
           L +     +++ GH+H+ +    +G      P+ C           +++  + PG    +
Sbjct: 184 LREHDAPVHVISGHLHRAMSALVDGVLHQVAPAPCHAVHLDQRADAVNSLVLEPGQVTVY 243

Query: 244 RTLELHADGTLTTEVHRLADTR 265
              ++   G L +++  + D  
Sbjct: 244 NWHDVT--GGLVSDLLPIGDYP 263


>UniRef50_C6DHP5 Metallophosphoesterase n=5 Tax=Proteobacteria RepID=C6DHP5_PECCP
          Length = 253

 Score =  200 bits (508), Expect = 5e-50,   Method: Composition-based stats.
 Identities = 66/247 (26%), Positives = 104/247 (42%), Gaps = 6/247 (2%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++++Q++D HL AQ    L G +  +  +A +  I  H  + DL+V +GDL+ D S+A+Y
Sbjct: 1   MKLIQLSDLHLTAQGGN-LHGRDPEQQLKAAIADINAHHRDTDLVVISGDLSDDGSAASY 59

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQD--AGISPAKRVFIGEQWQILLLDSQVF 132
              A  +A  + P     GNHD +    +            + V       ++LLDS   
Sbjct: 60  TFLASVLAELQVPWRVTMGNHDDREMFLAQFPTLVDENGFVQSVTTVGDDCVILLDSLHA 119

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL--RNAGELDTVL 190
           G   G L   +L W  R+L  A  ++  L LHH P+  G   LD   L    A  L  V 
Sbjct: 120 GEVAGTLCSERLTWFARQLQAAEGKNVFLFLHHPPMSIGLPALDSVRLAPEAAEALYQVC 179

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKP-HCSNFTLDTIAPGWRTLELH 249
            +F +V+++  GH+H+     W G        T  Q        F +   AP +      
Sbjct: 180 HRFGNVRHISAGHVHRPASGGWRGISFSTIRGTNHQSALRFAPGFEVSLEAPQYAIFLTT 239

Query: 250 ADGTLTT 256
            +G    
Sbjct: 240 EEGHTVH 246


>UniRef50_B1A0M0 Ser/Thr protein phosphatase family protein n=3 Tax=Bacteria
           RepID=B1A0M0_9BACT
          Length = 263

 Score =  200 bits (508), Expect = 6e-50,   Method: Composition-based stats.
 Identities = 65/243 (26%), Positives = 105/243 (43%), Gaps = 8/243 (3%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           + + ITD HL  +      GV T     A L+ I     +    V +GDLA+     AYQ
Sbjct: 4   KFIHITDIHLVDEGLLLNGGVPT-ARLDACLDDISRWHPDAAFCVISGDLAEFAEVEAYQ 62

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAG---ISPAKRVFIGEQWQILLLDSQVF 132
                +A +  PC  L GNHD +    S   D         +  F  EQ   L LD+   
Sbjct: 63  ALKARLAVYPLPCFLLIGNHDDRAVFQSVFPDHPKDMNEFVQHRFEIEQGVFLFLDTTKE 122

Query: 133 GV--PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
           G     G+L  ++L+WL+++LA+A ++ T L LHH P   G  ++D   L  A      L
Sbjct: 123 GRDVHEGQLCSYRLDWLKQQLAEAGDKPTYLFLHHPPFEIGIPYVDNIRLIEAEAFAKAL 182

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLD--TIAPGWRTLEL 248
                ++++  GH+H+   ++W G    + PS   Q   + ++   +     P +  + +
Sbjct: 183 RHGRDIRHVFYGHVHRMTYVNWRGISFTSLPSLNHQIPLNAASVNAEFCDEPPAYGVVLI 242

Query: 249 HAD 251
             D
Sbjct: 243 EDD 245


>UniRef50_C8SU16 Metallophosphoesterase n=1 Tax=Mesorhizobium opportunistum WSM2075
           RepID=C8SU16_9RHIZ
          Length = 276

 Score =  200 bits (508), Expect = 6e-50,   Method: Composition-based stats.
 Identities = 61/249 (24%), Positives = 108/249 (43%), Gaps = 7/249 (2%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++I+Q+TD HL  Q      G +  +   + +  I  H  +  L V TGDL +  +  +Y
Sbjct: 1   MKIIQVTDVHLGRQGER-RFGADLHQRLASCIAHINAHHADAALCVFTGDLTETGAPESY 59

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAG---ISPAKRVFIGEQWQILLLDSQV 131
                 +++   P   LPGNHD +  + +A  +         + V    +  +L LD   
Sbjct: 60  ADLRTALSTLSVPWRLLPGNHDRRVNLVAAFPEIPVDENGFVQSVHDSGEEVLLFLDCLA 119

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
            G   GEL   +L WLE +L  +  R   + LHH P+  G   LD  +L   G L  +L 
Sbjct: 120 EGRVEGELCGTRLAWLEARLEQSAGRPAYIFLHHPPVALGLPQLDPLALEQPGRLLGLLR 179

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFK--PHCSNFTLDTIAPGWRTLELH 249
              +V+++  GH+H+++     G    A      +F+     S+ T++   P +  + + 
Sbjct: 180 DHGNVRHIFFGHVHRDIAGTVAGIPFSAQRGLHARFELALDRSSETVEQAPPSYAVILID 239

Query: 250 -ADGTLTTE 257
            A+  +   
Sbjct: 240 SANQRVVVH 248


>UniRef50_A7BW21 Cyclic AMP phosphodiesterase n=1 Tax=Beggiatoa sp. PS
           RepID=A7BW21_9GAMM
          Length = 248

 Score =  199 bits (506), Expect = 9e-50,   Method: Composition-based stats.
 Identities = 79/253 (31%), Positives = 122/253 (48%), Gaps = 16/253 (6%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQ-DQSSAA 73
           + I Q+TDTH+    +    G+     +  VL A+   + +  L+V +GDLA  +    A
Sbjct: 6   LVIAQVTDTHIGP-MNIKYRGIEPRRQFLDVLRALTKMKPD--LLVLSGDLAAVEGEPEA 62

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQ----DAGISPAKRVFIGEQWQILLLDS 129
           Y    + +     P + + GNHD    M +A Q    D            +  ++L LDS
Sbjct: 63  YAWIRDVLVKLPYPYLVMAGNHDHVVRMNNAFQLQETDISQGMLFFSRTIKDKRLLFLDS 122

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLD-QHSLRNAGELDT 188
             +      +++ QLEWL+ +L D   +  LL +HH PL  GCS++D  H L+N  E+  
Sbjct: 123 SPY-----RIAKQQLEWLKEELNDYH-KQVLLFVHHPPLRCGCSFMDDHHGLQNGEEVWQ 176

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLEL 248
           VL +FP V+++ CGH H E  +  +G+ +  TPST  Q       F +D   PGWR +E 
Sbjct: 177 VLEQFPQVQHIFCGHYHTEKTIIQSGKSVHLTPSTVFQINAENPKFAIDHTNPGWRMIE- 235

Query: 249 HADGTLTTEVHRL 261
             D  + T V  L
Sbjct: 236 WDDTQVHTYVKYL 248


>UniRef50_A4F6Q6 Cyclic nucleotide phosphodiesterase n=7 Tax=Actinomycetales
           RepID=A4F6Q6_SACEN
          Length = 255

 Score =  198 bits (505), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 63/251 (25%), Positives = 101/251 (40%), Gaps = 10/251 (3%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
            + I  ++D H          G  + E  +  L+ +R      D +V TGD+A       
Sbjct: 2   TMAIAHLSDPHTTTGAQ----GDESVERLRRGLDCVRALDRLPDCVVITGDVADGGHRQE 57

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDA----GISPAKRVFIGEQWQILLLDS 129
           Y+     IA F  P     GNHD    +           G   A+       + ++ LDS
Sbjct: 58  YEAVRAVIADFPVPVHLTTGNHDDPRGLAEVFGGTDVLGGAREARYAVDYPGFTLVALDS 117

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
            + G P G L   QL WL+  LA  P+   ++ +HH P+  G  +LD   + +A E   V
Sbjct: 118 HMPGSPGGRLGADQLAWLDDVLARRPDVPAVVCVHHPPVAVGIPYLDGMGMEDAAEFAGV 177

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQ--FKPHCSNFTLDTIAPGWRTLE 247
           +A+  +V  +L GH+H+ +  D+ G  L   PST +Q  F        L      +    
Sbjct: 178 IARHRNVARVLAGHVHRAVVADFAGATLTTAPSTHIQIGFTTGEDVPPLHADPASFLLHL 237

Query: 248 LHADGTLTTEV 258
           +     +T  +
Sbjct: 238 IDGASAVTHTL 248


>UniRef50_C6A0T0 Predicted phosphohydrolase n=6 Tax=Thermococcus RepID=C6A0T0_THESM
          Length = 504

 Score =  198 bits (505), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 57/260 (21%), Positives = 115/260 (44%), Gaps = 18/260 (6%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++I  I+DTH+ +           ++ Y   L A   +  +++L++ TGD+  D     Y
Sbjct: 2   IKIAHISDTHITSG--------EAYKGYAYDLIANEINTLDYNLVIHTGDVTNDGLREEY 53

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
           +  +  +   + P + LPGNHD +   Y   Q   I P   ++  +   I+  DS +  +
Sbjct: 54  ERASYELKKIQKPLIVLPGNHDARNVGYELFQK-YIGPLNGIYEWKDLVIIWTDSTIPDL 112

Query: 135 PHGELSEFQLEWLERKLAD-APERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKF 193
             G +  ++  WL+ KL + + ++  ++  HHH +P   +  +++ L NAG++  +L K 
Sbjct: 113 NDGRIGGYKFRWLKEKLEEYSHKKFKIVASHHHLVPLPDTGRERNVLFNAGDVLELLLKH 172

Query: 194 PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGT 253
             V   LCGH H        G  L+   S C   +      T       +  +++  +G 
Sbjct: 173 E-VNLYLCGHKHVPNIYSVEG--LVVANSGCTSCRK-----TRKGDVNSYNMIKIKDNGK 224

Query: 254 LTTEVHRLADTRFQPDTASE 273
           ++  + R+ +   + D   +
Sbjct: 225 ISVTIKRVTEDIHKRDFTVK 244



 Score =  106 bits (265), Expect = 8e-22,   Method: Composition-based stats.
 Identities = 37/242 (15%), Positives = 84/242 (34%), Gaps = 20/242 (8%)

Query: 11  GEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQS 70
            +   RI+QI+      + + +       +  +  ++AI     + DL+V  GD+ +   
Sbjct: 253 KKRLFRIIQIS------ESNVSDRIYFREKVLKNAIKAINERY-KPDLVVHCGDIVEVGI 305

Query: 71  SAAYQHFAEGIASFRAPCVWLPGNH-DFQPAMYSALQDAGISPAKRVFIGEQWQILLLDS 129
              Y+         +   + +PG H D     Y   ++    P   +   E +  + + S
Sbjct: 306 ERYYKKAYALWEKIKGKKIIVPG-HNDITYLGYELFREYFGEPE--IIENENFTFIPIIS 362

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
             +  P G +     + L   L    +   ++++HH+  P   S  +   L + G +  +
Sbjct: 363 AQYETPIGVVGRIGQKILREHLKKYEDTFRVIIMHHNITPIPKS-REIGFLEDGGNVLKI 421

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELH 249
           L        +L GH    L +      ++   S              +     +  ++++
Sbjct: 422 LTD-EKANLVLTGHGGNSLGMKIEQTPIVNAGSISW-------ELHRNPFGNSFNLIDIY 473

Query: 250 AD 251
            D
Sbjct: 474 ED 475


>UniRef50_C1AX97 3',5'-cyclic-nucleotide phosphodiesterase n=24 Tax=Actinomycetales
           RepID=C1AX97_RHOOB
          Length = 318

 Score =  198 bits (504), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 67/280 (23%), Positives = 111/280 (39%), Gaps = 19/280 (6%)

Query: 12  EARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
                +L ++DTHL          V++  + + ++  I       D +V TGDL      
Sbjct: 16  RPSHVVLHLSDTHLV-DDDLLYGAVDSEATLRQIVTEIEASHARPDALVFTGDLTDRGQP 74

Query: 72  AAYQHFAEGIAS----FRAPCVWLPGNHDFQPAMYSAL--QDAGISPAKRVFIGEQWQIL 125
            AY+   E +        A  +W  GNHD +    + L  Q+    P   V   +  +I+
Sbjct: 75  GAYEKLREIVEPVAATLGAQVIWAMGNHDDRGHFRAELLGQEPTYEPVDHVHDVDGLRII 134

Query: 126 LLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGE 185
            LD+ V G  HGE+SE QL WL ++LA      ++L LHH P+P          LR+   
Sbjct: 135 TLDTTVPGHHHGEISESQLIWLAQQLAIPAPHGSILALHHPPVPCVLDLAVLVELRDQPR 194

Query: 186 LDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTL--DTIAPGW 243
           L  VL +   V+ +L GH+H      + G  +    +TC     +     L     A G+
Sbjct: 195 LADVL-RGSDVRSILAGHLHYSTTATFAGIPVSVASATCYTQDLNVPAGALRGRDGAQGY 253

Query: 244 RTLELHADGTLTTEV---------HRLADTRFQPDTASEG 274
             + ++ +  + + V           +          +EG
Sbjct: 254 NLVHVYPETVVHSVVPIGSYDTVGEYVTAEETARRLVAEG 293


>UniRef50_A0NQD3 Ser/Thr protein phosphatase family protein n=1 Tax=Labrenzia
           aggregata IAM 12614 RepID=A0NQD3_9RHOB
          Length = 272

 Score =  197 bits (502), Expect = 3e-49,   Method: Composition-based stats.
 Identities = 55/255 (21%), Positives = 99/255 (38%), Gaps = 10/255 (3%)

Query: 20  ITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAE 79
           +TD HL  +        +T    +  + +++    + D +V TGD+        Y     
Sbjct: 1   MTDLHLRPRGLACYRVSDTNMLAERAIRSLQSLTPKPDALVITGDITDGNDPREYALARS 60

Query: 80  GIASFRAPCVWLPGNHDFQPAMYSALQDAGI------SPAKRVFIGEQWQILLLDSQVFG 133
            ++    P   +PGNHD    M   L                       +++ LD+ + G
Sbjct: 61  ILSRVDMPVFLVPGNHDGTQVMRRELAGFPGLAGSLDDKICYTADIADIRLIALDTHIPG 120

Query: 134 VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKF 193
            P G L + QL+WL+ +L ++  + TL+ LHH P  +G   +D   L +A  L  V++  
Sbjct: 121 DPRGRLGQAQLDWLDGQLKESS-KTTLIALHHPPALSGIRHMDDIGLVDADALAEVVSPH 179

Query: 194 PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQF--KPHCSNFTLDTIAP-GWRTLELHA 250
            HV   LCGH+H+ +   + G+ +   PST  Q           +    P  +       
Sbjct: 180 RHVARFLCGHLHRPIIASFAGKVMTLAPSTGHQVVLDLTEDGPAMFNFEPAAYFLHYHSP 239

Query: 251 DGTLTTEVHRLADTR 265
              + + +  +    
Sbjct: 240 KTGVVSHMAYVEAFP 254


>UniRef50_Q982B7 Mll9148 protein n=1 Tax=Mesorhizobium loti RepID=Q982B7_RHILO
          Length = 325

 Score =  197 bits (501), Expect = 4e-49,   Method: Composition-based stats.
 Identities = 62/261 (23%), Positives = 94/261 (36%), Gaps = 7/261 (2%)

Query: 14  RVRILQITDTHLFAQKHEALLG-VNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA 72
            + I  ++D H+         G V+         E +       D++V TGDLA      
Sbjct: 40  SMIIAHLSDLHIRETGKPFASGNVDCTARAAQAFERVANMTPRPDMMVVTGDLADSGQIG 99

Query: 73  AYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDA--GISPAKRVFIGEQWQILLLDSQ 130
            YQ   E       P     GNHD +    +   +        +     ++ +++ LD+ 
Sbjct: 100 EYQLLKELTEGLPFPVHLALGNHDIRENFLAVFPEKKGPGGFVQFCVEHDKLRVIGLDTL 159

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRN-AGELDTV 189
           V G   G L   +L +L   L + P   TL+LLHH P   G    D   L + A EL  +
Sbjct: 160 VEGEGLGRLCSERLSYLRDCLQERPNTSTLILLHHPPFAFGGGIYDAVRLIDGARELGEI 219

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPST---CVQFKPHCSNFTLDTIAPGWRTL 246
           +     V  LLCGH H+ +D  WNG      PS    C         F      P ++  
Sbjct: 220 ITANKQVVRLLCGHHHRAIDCLWNGTLASVAPSVVSSCHLQLGDVRVFKNINEPPAFKLH 279

Query: 247 ELHADGTLTTEVHRLADTRFQ 267
            L  +    +    + D    
Sbjct: 280 VLVPESGFVSHNVFVEDFGPA 300


>UniRef50_A5FX65 Metallophosphoesterase n=1 Tax=Acidiphilium cryptum JF-5
           RepID=A5FX65_ACICJ
          Length = 282

 Score =  197 bits (501), Expect = 4e-49,   Method: Composition-based stats.
 Identities = 68/266 (25%), Positives = 102/266 (38%), Gaps = 14/266 (5%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + I  I+D H+      A   V T    + VL  +       + IV TGDL        Y
Sbjct: 1   MLIAHISDLHVRPVGRPANRVVETNMMAERVLRRVATLDPAPEAIVITGDLVDCGRDDEY 60

Query: 75  QHFAEGIAS-FRAPCVWLPGNHDFQPAMYSALQDAGI-----SPAKRVFIGEQWQILLLD 128
           +     +      P   +PGNHD + A  +AL             +       +++++LD
Sbjct: 61  EELNRLLDRKLPCPVYVVPGNHDRREAFRAALGHLPGVTADPDFVQYSADIGPFRLIMLD 120

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           S V G  HGEL   +L +L+  L  A  R  L+ LHH P+  G + +D   LR++  L  
Sbjct: 121 SVVPGAGHGELCPQRLAFLDAALEAAAGRKVLIGLHHPPVITGVAAMDSIMLRSSEALLA 180

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLEL 248
             A   +V  +L GH H+ +     G  LL+ P+       H S  T D  A  +    L
Sbjct: 181 RAAAHGNVAAILSGHHHRAIHAAHGGTMLLSVPAAAG----HQSEITFDPKARAY--FHL 234

Query: 249 HADGTLTTEVHRLADTRFQPDTASEG 274
              G     +             S G
Sbjct: 235 EPGGIFL--LRWTEPEGLTAMLDSVG 258


>UniRef50_B5J8T8 Ser/Thr protein phosphatase family protein n=2 Tax=Rhodobacteraceae
           RepID=B5J8T8_9RHOB
          Length = 259

 Score =  197 bits (501), Expect = 4e-49,   Method: Composition-based stats.
 Identities = 57/258 (22%), Positives = 105/258 (40%), Gaps = 10/258 (3%)

Query: 15  VRILQITDTHLFAQKHEA-LLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
           + I  I+D H+FA+  E  L+  +  ++ + V+  I     +   ++ TGDL    S+  
Sbjct: 1   MLIAHISDFHIFAEAPETSLVRPDAADAARKVVADIAAFTPQIGAVMFTGDLTDGGSAED 60

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSAL----QDAGISPAKRVFIGEQWQILLLDS 129
           Y    + ++    P   +PGNHD +P M ++                      +IL LD+
Sbjct: 61  YALLTDILSPLDVPVFVVPGNHDARPGMRASFAGKLPFEADPFLNYEAWFNDIRILALDT 120

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRN-AGELDT 188
              G   G L + QL WL  +LA      TL+L+HH   P+  + LD  +L++   + + 
Sbjct: 121 LWDGQIAGRLDQTQLVWLAERLAVPHHGLTLILMHHPAFPSQMAPLDAMTLQDGRADFER 180

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQ----FKPHCSNFTLDTIAPGWR 244
           ++A +     +L GHIH+     W+G     +     Q      P      +      + 
Sbjct: 181 LIANYNEPLRILSGHIHRPFQTLWHGVFCAVSGGPAFQHALTLDPDADEPGIVAEPYAYF 240

Query: 245 TLELHADGTLTTEVHRLA 262
              +    +++     +A
Sbjct: 241 IHRITDATSVSIHTRYVA 258


>UniRef50_A5WBU9 Calcineurin phosphoesterase C-terminal domain protein n=1
           Tax=Psychrobacter sp. PRwf-1 RepID=A5WBU9_PSYWF
          Length = 340

 Score =  197 bits (501), Expect = 4e-49,   Method: Composition-based stats.
 Identities = 89/306 (29%), Positives = 130/306 (42%), Gaps = 51/306 (16%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVN-------------------------------- 37
             +  V ILQ+TD HL+    +A    +                                
Sbjct: 35  TDDGTVNILQLTDLHLYFDTPKATHEQDINKDSAHQTITGICQNNSAKRGNPHSADAINH 94

Query: 38  -------TWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVW 90
                   + S++A L          DLIV TGDL  +     YQH  + +     P   
Sbjct: 95  SVTPVIHNYASFEACLTQALSEDVRCDLIVVTGDLVSEIHPQLYQHLYQRLHQSGIPFAC 154

Query: 91  LPGNHDFQPAMYSALQDAGISP----------AKRVFIGEQWQILLLDSQVFGVPHGELS 140
           + GNHD    +   L     S           ++       W+IL ++S V G   G + 
Sbjct: 155 IAGNHDVTDEIGKDLPFEQRSFEPHEPDSRLLSRYSMKLNGWEILFINSSVPGQIFGRIG 214

Query: 141 EFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLL 200
              L WL +KLA++     ++ +HHH LP   +W+D H  ++A E    +A F  +K ++
Sbjct: 215 NKNLYWLSQKLANSH-HPVIIAMHHHLLPMHSAWIDAHITQDATEFWQTVAPFNALKAVV 273

Query: 201 CGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA-PGWRTLELHADGTLTTEVH 259
            GH+HQ     + G +L +TPST  QFKP C +FTLD  A PG+R L L A+GTL + V 
Sbjct: 274 GGHVHQSSTRSYQGVQLYSTPSTGYQFKPGCDDFTLDDEAKPGYRWLSLKANGTLQSWVV 333

Query: 260 RLADTR 265
           RL D  
Sbjct: 334 RLEDNA 339


>UniRef50_D2U008 3',5'-cyclic-nucleotide phosphodiesterase n=1 Tax=Arsenophonus
           nasoniae RepID=D2U008_9ENTR
          Length = 242

 Score =  196 bits (500), Expect = 5e-49,   Method: Composition-based stats.
 Identities = 61/238 (25%), Positives = 118/238 (49%), Gaps = 4/238 (1%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++I+Q+TD HLF+ + + L GV T++S   +++ I  ++ ++D I+ TGD++QD++  +Y
Sbjct: 1   MKIIQLTDLHLFSDRTQKLFGVVTYDSLNKIIDHILINEGDYDAIILTGDISQDETIESY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
           Q   E +     P  ++ GNHD++  +                    W  + +D+  +G 
Sbjct: 61  QLANEMLIRLNKPIHYIHGNHDYKSNLDLIFNIHNPIEN---LSIPYWDFISVDTVEYGK 117

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
             G +S+ +   L++K++++ E +  L++HHH L  G   +D   L N  +L   +    
Sbjct: 118 DSGFISDKEFRLLKKKISESKENNIALVMHHHCLKLGTPLIDDCMLLNNNQLLRFIDGEN 177

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADG 252
            +K ++CGH H    L  N   L   P+ C Q+K      +++ I  G+R      + 
Sbjct: 178 KIKLIMCGHAHGNYKLKHNNSTLEVCPAVCFQWKKGTETPSIENI-SGYRKFSFFKEN 234


>UniRef50_C6BIA6 Metallophosphoesterase n=2 Tax=Ralstonia pickettii
           RepID=C6BIA6_RALP1
          Length = 284

 Score =  196 bits (499), Expect = 6e-49,   Method: Composition-based stats.
 Identities = 58/279 (20%), Positives = 104/279 (37%), Gaps = 18/279 (6%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
            +  LQ+TD H+      A   V++       +  I     + D IV TGDL    +   
Sbjct: 2   PMHFLQLTDLHIKRPGRLAYRRVDSAAYLARCVAHILAQPEKPDAIVLTGDLVDAGAPEE 61

Query: 74  YQHFAEGIASF---RAPCVWLPGNHDFQPAMYSALQDA---------GISPAKRVFIGEQ 121
           Y H    +A         + + GNHD + A   A  D               +       
Sbjct: 62  YAHLRAVLAPLDAAGIHMLPVLGNHDGRDAAREAFVDWLAPIPADAQDTRAFQYWTDIGD 121

Query: 122 WQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL- 180
            +++++D+   G P G L   +L+WL   LA   +R T++ +HH P   G   +D  SL 
Sbjct: 122 VRLIVIDTLDTGHPGGRLGVQRLDWLAEALAHETQRPTVIAMHHPPFATGIGHMDVQSLA 181

Query: 181 -RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSN---FTL 236
             +      ++    +V+ ++CGH+H+ +D+ + G      PS   Q             
Sbjct: 182 PEDIPAFAQIVRAAGNVERIICGHLHRSIDVRFAGTVASTCPSPAHQVALDLDPNAAPGF 241

Query: 237 DTIAPGWRTLELHADGTLTTEVHRLADTRFQ-PDTASEG 274
               P ++         L + +  + +     P   ++G
Sbjct: 242 VMEPPAYKVHAWVPGQGLVSHLAYVGEFDGPHPFFEADG 280


>UniRef50_C5T0E1 Metallophosphoesterase n=1 Tax=Acidovorax delafieldii 2AN
           RepID=C5T0E1_ACIDE
          Length = 267

 Score =  196 bits (499), Expect = 6e-49,   Method: Composition-based stats.
 Identities = 72/268 (26%), Positives = 108/268 (40%), Gaps = 18/268 (6%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           + + +TDTHL  +   AL G++     Q  +E I  H  +   +V TGDL       AY+
Sbjct: 6   KYIHLTDTHLVKEA-GALYGLDPKLRLQQAVEHINCHHADARAVVITGDLTHYGHDNAYE 64

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAG---ISPAKRVFIGEQWQILLLDSQVF 132
           H  E +A+   P   + GNHD +                  + V   E++  + LD+   
Sbjct: 65  HLRECLAALSMPVYPILGNHDSRVNFVRHFPHIPCDANGFVQYVVQLERYTAIFLDTNEP 124

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
           GV  G   E + +WL   L  A E+  LL +HH   P G + +D  SLRN G  +  +A 
Sbjct: 125 GVHWGVFCEQRAQWLRAAL-QAAEKPVLLFMHHPFFPIGITSMDDISLRNTGPFEAAIAS 183

Query: 193 F-PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLD----TIAPGWRTLE 247
           F P + +   GHIH+ +     G       ST         + +L+       P +  L 
Sbjct: 184 FEPRIAHCFFGHIHRPIFGSVRGIPYSTLRSTNHDVALVLQDPSLNIVGKNENPQYGVLL 243

Query: 248 LHADGTLTTEVHRLADTRFQPDTASEGY 275
           L     L      L         +SEGY
Sbjct: 244 LREGQVLLHLEDYLD--------SSEGY 263


>UniRef50_B6WYD4 Putative uncharacterized protein n=1 Tax=Desulfovibrio piger ATCC
           29098 RepID=B6WYD4_9DELT
          Length = 274

 Score =  195 bits (497), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 67/266 (25%), Positives = 102/266 (38%), Gaps = 15/266 (5%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + ILQI+D HL      +   V+T    +     +       D IV TGDLA      AY
Sbjct: 1   MEILQISDLHLRGDGKLSFRKVDTPACLRTAAAYLHALNRMPDAIVITGDLADSGDEHAY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAK------RVFIGEQWQILLLD 128
               E +     P   +PGNHD +  M + L+      +             + ++++LD
Sbjct: 61  HMLYEALGDLPVPIYAVPGNHDRRDRMRAILKGWVPEESPVPPRVCHCVDMGELRLVMLD 120

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           S   G   G   E    WL+  L +   R  L+ +HH P   G   +D+     A  L  
Sbjct: 121 SMEPGSHSGHCPEAMARWLDACLQEDSSRPALVFMHHPPFITGMGAMDE-PFEGADLLRD 179

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA---PGWRT 245
           VL++ P  +   CGH+H+ +   W     L  PS  +Q     S    DT     PG+  
Sbjct: 180 VLSRAPWARLC-CGHMHRPIFTAWAQGLALTVPSISMQIDLDLSPEGGDTFRMEMPGY-M 237

Query: 246 LELHADGTLTTEVHRLADTRFQPDTA 271
           L       L + V ++       D +
Sbjct: 238 LHHWDGSHLNSHVCQIPAD---VDFS 260


>UniRef50_B0P519 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=B0P519_9CLOT
          Length = 305

 Score =  195 bits (496), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 54/278 (19%), Positives = 101/278 (36%), Gaps = 30/278 (10%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHE--FDLIVATGDLAQDQSSA 72
           ++++QI+D HL      +    +T ++    ++     +     +  V TGDL++  +  
Sbjct: 15  MKVIQISDFHLRGDGKLSFQKADTMKALHQTIDYFCSMKDYELPEFFVVTGDLSEGGTRE 74

Query: 73  AYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGI------SPAKRVFIGEQWQILL 126
            Y+   EG+     P   +PGNHD +        +                     ++++
Sbjct: 75  GYEFMREGLRKLPRPVYIVPGNHDKRDFFLEMFTEETPVKEDIKPYICYTIDEYPVRVIV 134

Query: 127 LDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGEL 186
           +D+       G LS+   EWLE ++ + PE+ TL+  HH P   G   +D+     A  L
Sbjct: 135 IDTSKPSCHSGGLSDRVAEWLEERITEYPEKPTLVFTHHPPFVTGLPAMDE-GFDQADRL 193

Query: 187 DTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFK------------------ 228
             +L K  +V    CGH+H  +   W+    +  P   +Q +                  
Sbjct: 194 AQILNKHENVTLC-CGHMHTAIFTSWHKIPCVTCPPIAMQMEVDFRGKNDINLTEEEKKE 252

Query: 229 -PHCSNFTLDTIAPGWRTLELHADGTLTTEVHRLADTR 265
                        PG+   +L  D  + T    +    
Sbjct: 253 EFKGGGDRFFLGNPGYLIHDLQGD-RINTHYQTIPTGA 289


>UniRef50_A9FYQ8 Phosphodiesterase n=6 Tax=Rhodobacteraceae RepID=A9FYQ8_9RHOB
          Length = 276

 Score =  195 bits (496), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 58/253 (22%), Positives = 101/253 (39%), Gaps = 12/253 (4%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++I+ I+D HL     E + G++    +   L  +  +    D IV TGDL      AAY
Sbjct: 1   MKIIHISDIHLTIPGEE-MGGLDPHARFSRALANVAENHANADRIVITGDLTHWGEVAAY 59

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAG---ISPAKRVFIGEQWQILLLDSQV 131
           +     +A    P   L GNHD +        D               ++ +++ LDS  
Sbjct: 60  EALKSALAEVSIPVRLLIGNHDDRDTFRKVFTDHPVDANGFVNHAETLDETRLIYLDSVG 119

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL--RNAGELDTV 189
                G     + +WL+ +L  A      + LHH+P+P G    D+ +L   +      +
Sbjct: 120 DKTHAGHFCAVRRDWLKAELTAA--GRARIFLHHNPMPVGLPAEDKIALVPEDRAAFKAL 177

Query: 190 LAKF-PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLD---TIAPGWRT 245
           L  +   + Y+  GH+H  +   + G    + PST  Q  P  +   L     +AP +  
Sbjct: 178 LEAYGDRIDYIHFGHVHAPIHGRFAGIPFASVPSTGNQSLPDLNETELLKGAPMAPAYFV 237

Query: 246 LELHADGTLTTEV 258
           L +  + T   ++
Sbjct: 238 LSIDGNDTTIHQI 250


>UniRef50_Q7NZT6 3',5'-cyclic-nucleotide phosphodiesterase n=1 Tax=Chromobacterium
           violaceum RepID=Q7NZT6_CHRVO
          Length = 244

 Score =  195 bits (495), Expect = 2e-48,   Method: Composition-based stats.
 Identities = 80/244 (32%), Positives = 119/244 (48%), Gaps = 2/244 (0%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +RI Q+TD HLFA +   LLG +T  +   VL A+R      + ++ TGD++QD+S A+Y
Sbjct: 1   MRIAQLTDLHLFADRQGRLLGRDTHAALDGVLAALRT-VEGVEAVLLTGDVSQDESEASY 59

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
              AE +A+   P  W+ GNHD + AM                    W  + +DS V G 
Sbjct: 60  HLAAEALAALGVPVHWIAGNHDDRAAMTRVFAGYAFLRPLETLALGGWTFIGVDSCVAGQ 119

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
             G LS+  L+ L R L +A +    ++LHHHPL  G   LD   L  A     + A   
Sbjct: 120 DGGRLSDAGLDRLRRLLDEAGDGPAAVVLHHHPLAVGTPLLDDCMLAPASPFWRIAAASA 179

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTL 254
            +K  +CGH+H E  + + G+ L   P+TC Q++    +  +D    G+R  +   DG L
Sbjct: 180 ALKLAICGHVHGEHSIAYRGKMLEVGPATCFQWRRDACDIEIDD-RHGYRLFDFDGDGYL 238

Query: 255 TTEV 258
              V
Sbjct: 239 VRTV 242


>UniRef50_B3TB35 Putative calcineurin-like phosphoesterase n=1 Tax=uncultured marine
           microorganism HF4000_APKG8K5 RepID=B3TB35_9ZZZZ
          Length = 245

 Score =  194 bits (494), Expect = 2e-48,   Method: Composition-based stats.
 Identities = 62/244 (25%), Positives = 104/244 (42%), Gaps = 12/244 (4%)

Query: 42  YQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAM 101
            +  ++ +     + D++VATGDL    S   Y +  E +A        +PGNHD + A+
Sbjct: 2   LRDCVDHLSALDPQPDIVVATGDLTYLGSPEEYAYLRELLAPLECSVFLIPGNHDGRGAL 61

Query: 102 YSALQDAGISP---------AKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLA 152
             A  D G  P                   +++ LD+ V G P G L E Q+ WL+  L 
Sbjct: 62  REAFADQGYFPEPSGGDRDFLNYTVEDYPLRLIALDTVVPGKPGGWLDETQIAWLDECLG 121

Query: 153 DAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDW 212
           ++P R T++L+HH P  +G + +D     N+  L  V+A+ P V+ ++CGH+H+ + L W
Sbjct: 122 ESPSRPTMILMHHPPYVSGIAHMDAMMCGNSDALGAVVARHPQVERIICGHLHRPVHLRW 181

Query: 213 NGRRLLATPSTCVQFKPHCSNFT---LDTIAPGWRTLELHADGTLTTEVHRLADTRFQPD 269
           +G  +   PS   Q   +    +        P         +  L T +  + D      
Sbjct: 182 HGTVVCTAPSPGFQVVLNLGKESPAEWIREPPACCLHLWRPETGLVTHISYIGDYGGPQP 241

Query: 270 TASE 273
               
Sbjct: 242 FPWT 245


>UniRef50_Q0FF25 Putative uncharacterized protein n=1 Tax=Rhodobacterales bacterium
           HTCC2255 RepID=Q0FF25_9RHOB
          Length = 275

 Score =  194 bits (493), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 51/269 (18%), Positives = 111/269 (41%), Gaps = 13/269 (4%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           ++L I+D HL ++K   ++G++    +   L        + + ++  GD+      + Y+
Sbjct: 3   KVLVISDIHLRSKKRN-IIGLDPLRQFTEALSHALKKHPDAEHMILIGDMTHSGHVSEYE 61

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV---FIGEQWQILLLDS--- 129
                  +++ P  ++ GNHD +        +  +     +          ++ LD+   
Sbjct: 62  MLKRATNTYKIPITFMLGNHDNRSNFKKVFPEIPLDNEGYLQKKISLGDDVLICLDTLNS 121

Query: 130 --QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELD 187
             Q+     G+L E +LEWLE++L+ A  +   +  HH P   G   +D+  L N+ +L 
Sbjct: 122 SPQLEIEHEGKLCEKRLEWLEQELSQAKNKRISIFTHHPPHNIGFPGMDKIKLSNSADLF 181

Query: 188 TVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKP---HCSNFTLDTIAPGWR 244
            ++ K+ + K++  GH+H+ +  + NG       STC Q         +         + 
Sbjct: 182 NIIKKYKNTKHIFSGHVHRSISGNTNGIGFTIFKSTCHQMPMDLLSLDSSLSVKEPAAYG 241

Query: 245 TLELHADGTL-TTEVHRLADTRFQPDTAS 272
            +       +  TE +++A      +  +
Sbjct: 242 IVLFDDQSIIAHTEDYQIAKQADPSNLDA 270


>UniRef50_P05675 Uncharacterized protein syc0937_d n=2 Tax=Synechococcus elongatus
           RepID=Y937_SYNP6
          Length = 255

 Score =  193 bits (492), Expect = 4e-48,   Method: Composition-based stats.
 Identities = 70/251 (27%), Positives = 113/251 (45%), Gaps = 11/251 (4%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
            + I QITD HL      AL G  T     AV   ++    +  L+     L++D S A+
Sbjct: 11  TLSIAQITDLHLLVDPQAALRGCVTTPRAAAVFGNLKQRSPDLLLLSGD--LSEDGSPAS 68

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFG 133
           Y+   + +     P + + GNHD    +      +     + V+  + W+I+ LDS    
Sbjct: 69  YERLRDWVEELGCPAIAIAGNHDQPERLTEICGRSPF-MGEPVYSIQGWRIIALDSYQPK 127

Query: 134 VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKF 193
              G L   QL+WL+++L +     TLL+LHH P+  G + +D   L++  E   V+A  
Sbjct: 128 RIDGRLRGDQLDWLDQRLGEDSS-PTLLMLHHPPVLIGVTKMDAIGLKDGPEFLEVIAHH 186

Query: 194 PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGT 253
             V+ +L GH HQ           L  P+T +QF           +  GWR+LEL  DG+
Sbjct: 187 QQVRLVLSGHAHQAFIQGRGLTTFLGCPATAMQFDQP-------ELPAGWRSLELEPDGS 239

Query: 254 LTTEVHRLADT 264
             +++H +   
Sbjct: 240 WRSQIHWVDTD 250


>UniRef50_B7QYI4 3',5'-cyclic-nucleotide phosphodiesterase, CpdA n=1 Tax=Ruegeria
           sp. R11 RepID=B7QYI4_9RHOB
          Length = 275

 Score =  193 bits (492), Expect = 4e-48,   Method: Composition-based stats.
 Identities = 52/232 (22%), Positives = 93/232 (40%), Gaps = 5/232 (2%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
            ++++ ++D H        +LG +      A ++ I  H  +    V +GD+A+  ++  
Sbjct: 10  SMKLIWMSDLHFQHSGE--ILGHDPQLRLDAAIDYINQHHSDASYCVISGDMAETATARN 67

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDA---GISPAKRVFIGEQWQILLLDSQ 130
           Y   A+ +     PC+ + GNHD +  + +  Q          +         IL LD+ 
Sbjct: 68  YADLADRLDQLAIPCLPMVGNHDDRDLLRAQFQVPDSCMDGFLQYSVDTPAGLILCLDTL 127

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
             G   GE    +  WL   L  A +R  LL LHH P+P G    D   L +      ++
Sbjct: 128 KPGASEGEFCAERARWLTSTLDAAQDRAVLLFLHHPPMPLGLPVQDSARLEHGARFLEII 187

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPG 242
               ++++L  GH+H+ +     G    A  S   Q  P    +  ++  P 
Sbjct: 188 EGRANLRHLCVGHVHRSVTGTIRGIPFTALRSVLYQAPPPQPEWDWNSFTPS 239


>UniRef50_A4C954 Cyclic 3',5'-adenosine monophosphate phosphodiesterase n=2
           Tax=Alteromonadales RepID=A4C954_9GAMM
          Length = 263

 Score =  193 bits (492), Expect = 5e-48,   Method: Composition-based stats.
 Identities = 74/256 (28%), Positives = 121/256 (47%), Gaps = 9/256 (3%)

Query: 11  GEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQS 70
            ++++R   I+D HLFA+ +E   GVN  +S + VL  +     +   ++  GDL QD S
Sbjct: 11  DKSQLRFAHISDCHLFAEVNECYFGVNCCDSLRLVLTDLAEQTLD--FVIFGGDLTQDHS 68

Query: 71  SAAYQHFAEGI--ASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIG--EQWQILL 126
            A+YQ FA+ +  A    P +WLPGNHD       A          R          + L
Sbjct: 69  LASYQLFAQLVNEAQLPCPVLWLPGNHDELDCYQQAFSMLPSHVISRAKWVQSPNLTVAL 128

Query: 127 LDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGEL 186
           ++S+    P G +    L  L  K+  A E++ ++  HHHP      +LD+H L N    
Sbjct: 129 VNSKGP-TPAGWVEPAHLTELVCKIKTAAEKN-VVFCHHHPKAI-AGYLDKHILENGEWF 185

Query: 187 DTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTL 246
            T LA+   V  +  GH+H +         + ATP+T +QF  + + +  + +  G+R +
Sbjct: 186 LTQLAQTEQVTTVFHGHVHNDYLQQHGELSIYATPATSIQFVKNSATWQQEDLGAGYRII 245

Query: 247 ELHADGTLTTEVHRLA 262
             +  G +++EV  LA
Sbjct: 246 HSNQLGEISSEVVWLA 261


>UniRef50_A3WHQ7 Putative cAMP phosphodiesterase n=1 Tax=Erythrobacter sp. NAP1
           RepID=A3WHQ7_9SPHN
          Length = 294

 Score =  191 bits (487), Expect = 1e-47,   Method: Composition-based stats.
 Identities = 59/270 (21%), Positives = 102/270 (37%), Gaps = 17/270 (6%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
           + +  V I QITDTH+  +        N +  ++ VL  +   +   D+++ +GDL    
Sbjct: 3   SEKRGVLIAQITDTHVGFEPEAGENEFN-FVRFRNVLGHLLNQKILPDMLILSGDLTDGG 61

Query: 70  SSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGI--SPAKRVFIGEQ-----W 122
              +Y    E +A    P   +PGNHD +  +  A  D       A+     +       
Sbjct: 62  QPDSYARIRELVAECPFPVHVIPGNHDSRDELLKAFPDCPTADGFAQFAIDCDDGAGNAL 121

Query: 123 QILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRN 182
           ++L LDS   G   G   E +  WL ++LA  P+  T++ +HH P+ AG  W+D      
Sbjct: 122 RVLCLDSFEPGRHGGAFCEVRAAWLAKELAAHPDTPTVIFMHHPPVVAGIDWMDPKPGEA 181

Query: 183 A-GELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPH--------CSN 233
                   +     +  +  GH+H+ L     G  L  TP+                  +
Sbjct: 182 WFKRFHDTVKGHDQIISIQAGHLHRPLHSVVEGIPLSVTPAVAPAVALDLRPMDAEVADS 241

Query: 234 FTLDTIAPGWRTLELHADGTLTTEVHRLAD 263
             +    P + +L L   G   +    +  
Sbjct: 242 RPIVAAEPPFYSLHLWRGGEFVSHFQPVGH 271


>UniRef50_C7S9W5 Protein icc n=17 Tax=Bacteria RepID=C7S9W5_ECOLX
          Length = 274

 Score =  191 bits (486), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 50/220 (22%), Positives = 91/220 (41%), Gaps = 6/220 (2%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + +  I+DTH  ++  +    ++   +   V+  +   +   D +V +GD+        Y
Sbjct: 1   MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALRERPDAVVVSGDIVNCGRPEEY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSAL----QDAGISPAK--RVFIGEQWQILLLD 128
           Q   + + S   P   +PGNHD +      L       G  P     V      ++L +D
Sbjct: 61  QVARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDPQNMRYVVDDFATRLLFID 120

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           S   G   G L++  + WLE +L +  ++   + +HH PLP G + +D  +  N   L  
Sbjct: 121 SSHAGTSKGWLTDETIGWLEAQLFEGGDKPATIFMHHPPLPLGNAQMDPIACENGHRLLE 180

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFK 228
           ++ +FP +  + CGH H      +    +   P T  Q  
Sbjct: 181 LVERFPSLTRIFCGHNHSLTITQYLQALISTIPGTVHQVP 220


>UniRef50_A4EJU5 3',5'-cyclic-nucleotide phosphodiesterase, cpdA n=2
           Tax=Rhodobacterales RepID=A4EJU5_9RHOB
          Length = 262

 Score =  191 bits (486), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 53/247 (21%), Positives = 95/247 (38%), Gaps = 10/247 (4%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           +I+ ++D H        + G++     +A +  +  H  + D  V TGDL  D     Y 
Sbjct: 3   KIIWMSDPHFQMTG--TIDGLDPRVRLKAAITYLNTHYTDADFAVLTGDLVGDDIVEDYT 60

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQ---DAGISPAKRVFIGEQWQILLLDSQVF 132
             AE +A  +     L GN+D + +  + L    D      + V        + LD+   
Sbjct: 61  GIAEYLAKSQVSIYPLMGNNDERESFRAHLPLPADGMPDFIQYVVDTPDQTFICLDTHKV 120

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
           G   G+    +  WL++ LA  P +   + +HH PL  G    D+  L ++     +++ 
Sbjct: 121 GSHAGQFCSARQAWLDQVLAKDPLKPAYIFMHHPPLNLGLPPQDEIMLEDSDAFLDIVSA 180

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDT-----IAPGWRTLE 247
             +VK+L  GH+H+       G       +   Q       +  D+      AP    L 
Sbjct: 181 HNNVKHLFMGHVHRPTAGTVKGIPFATIGALSFQAPAPQPAWHWDSFVLAKEAPQLGVLL 240

Query: 248 LHADGTL 254
           +  D  +
Sbjct: 241 IENDKVV 247


>UniRef50_B6J9P9 3',5'-cyclic-nucleotide phosphodiesterase n=7 Tax=Coxiella burnetii
           RepID=B6J9P9_COXB1
          Length = 246

 Score =  191 bits (485), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 54/241 (22%), Positives = 110/241 (45%), Gaps = 4/241 (1%)

Query: 11  GEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQS 70
            +  ++I Q++D HL ++  E   G  +      V  AI     + D+I  TGD++ D +
Sbjct: 2   EDNCIKIAQVSDLHLTSENCETSRGRYSNAM--NVFSAI-SLSGQHDMIFITGDISDDYT 58

Query: 71  SAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQ 130
             +Y+   E +         +PGNHD    M   + +  +   + V     +  L +++ 
Sbjct: 59  ENSYKQLLEMLKKLTCRVFVIPGNHDDFNLMNKIIPEKYLFSPETVTSFNTFDFLFVNTV 118

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
           V G  HG L+   L  L+  L ++  +   +++HH+P+P      D++ L N  +   ++
Sbjct: 119 VNGEIHGLLTGQDLSLLQNHLENSGNKKKCMIMHHNPIPLNRKIYDKYMLLNYQDFLRII 178

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHA 250
             + +VK ++ GH+H +  + +      + P+TC Q K   S+  ++    G++   L  
Sbjct: 179 CLYDNVKLVIFGHVHNDYTISYRQTLFSSAPATCYQIKKFESDIIIEEK-YGYKNYFLFE 237

Query: 251 D 251
           +
Sbjct: 238 N 238


>UniRef50_D1XS68 Metallophosphoesterase n=1 Tax=Streptomyces sp. ACTE
           RepID=D1XS68_9ACTO
          Length = 262

 Score =  191 bits (485), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 67/266 (25%), Positives = 100/266 (37%), Gaps = 28/266 (10%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           +  ++D HL   +  A                        D ++ TGD+    ++  Y  
Sbjct: 4   LAHLSDPHLDGTEESAARAHRAVAHLA-------GLPGRVDAVLITGDIVDRGTAEEYHQ 56

Query: 77  FAEGIASF--RAPCVWLPGNHDFQPAMYSAL---------------QDAGISPAKRVFIG 119
             E +A    R   +  PGNHD +      L                  G +P   V   
Sbjct: 57  AREVLAPLYERHEVLLCPGNHDSRAPYREVLLGGGGGGSGSGGGDDGGGGTAPVNEVRDV 116

Query: 120 EQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHS 179
              ++L+ DS V G P G L    L WL+  LA AP+R   + LHH P+P G  ++D+  
Sbjct: 117 GGVRVLMCDSSVPGRPEGLLEAATLSWLDDALAAAPDRPAFVALHHPPVPLGLPYIDRIG 176

Query: 180 LRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTC----VQFKPHCSNFT 235
           LR    L  VLA+   V  +LCGH H      + G  LL  P       + ++       
Sbjct: 177 LREPDALAKVLARHAQVVAVLCGHAHTAAATSFAGLPLLCAPGIASTALLPWEQGPDASW 236

Query: 236 LDTIAPGWRTLELHADGTLTTEVHRL 261
               AP      L+ +G LT+ V  +
Sbjct: 237 KTHGAPPALAFHLYEEGRLTSHVRAV 262


>UniRef50_A2C6L9 Serine/threonine specific protein phosphatase n=2
           Tax=Prochlorococcus marinus RepID=A2C6L9_PROM3
          Length = 263

 Score =  191 bits (485), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 76/264 (28%), Positives = 119/264 (45%), Gaps = 14/264 (5%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +R++Q++D HL A  H  +   N   ++Q  L+    H  +  L++ TGDL  D+S   Y
Sbjct: 1   MRLVQLSDPHLVAFNHRLVRDQNPLLNFQCALQQGMSHSPD--LLLITGDLCHDESWCGY 58

Query: 75  QHFAEGIASFR--APCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVF 132
               + + +         LPGNHD    + +AL     + A      +  +++LL S V 
Sbjct: 59  VLLRDELQNLSPSIKVAVLPGNHDNPLFIKAALGRHAFT-APADLNLDGVRLILLSSHVS 117

Query: 133 GVPHGELSEFQLEWLERKLA--DAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
           G   G+L E QL+WL+ +L+  +   R  ++ +HH PLP G SWLD   L +   L  +L
Sbjct: 118 GRTAGQLGESQLQWLDSRLSDIEQSGRPLVVAVHHPPLPIGSSWLDAIGLVDGEALIKLL 177

Query: 191 AKFPHVKYLLCGHIHQELDL---DWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLE 247
                +  ++CGHIHQ       +     +L  PST   FK            PG R +E
Sbjct: 178 TPVDELCAVVCGHIHQHWQGLFPERKDVLVLGCPSTLCSFKAVQPCLLGREDEPGGRLIE 237

Query: 248 LHADGTLTTEVHRLADTRFQPDTA 271
           L   G    ++ R +     PD  
Sbjct: 238 LDESGNFFEKLLRWS----YPDLD 257


>UniRef50_C6WAT1 Metallophosphoesterase n=1 Tax=Actinosynnema mirum DSM 43827
           RepID=C6WAT1_ACTMD
          Length = 245

 Score =  190 bits (484), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 69/249 (27%), Positives = 97/249 (38%), Gaps = 10/249 (4%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           +   +DTH          G +     + V+  +R      D  V TGD+  +     Y+ 
Sbjct: 4   LAHFSDTHFD-------GGDHAAPRAERVVGYLRGLARPVDAAVLTGDVVDNGLRVEYEE 56

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSAL--QDAGISPAKRVFIGEQWQILLLDSQVFGV 134
            A  +     P + LPGNHD +      L  +  G  P  RV    +  + L DS V G 
Sbjct: 57  AARVLGGLGRPLLALPGNHDSRSPFREVLLGEGPGDGPVNRVARVGEVVLALCDSTVPGQ 116

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
             G L++  LEWL+  LA+A    TL+ LHH P+P     LD   L     L  V+    
Sbjct: 117 DGGALADETLEWLDAVLAEAAGAPTLVCLHHPPVPVRHPVLDPIGLDAPERLARVVRGRK 176

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPS-TCVQFKPHCSNFTLDTIAPGWRTLELHADGT 253
            +  LLCGH H  +     G  +L+ P        P       D  AP      +  DG 
Sbjct: 177 GLLALLCGHSHSPMVGSLAGVPVLSAPGVVSTLAPPWEGEKPNDRGAPPALAFHVVEDGQ 236

Query: 254 LTTEVHRLA 262
           LTT    + 
Sbjct: 237 LTTHYRLVP 245


>UniRef50_B5JAZ3 Ser/Thr protein phosphatase family protein n=2 Tax=Rhodobacteraceae
           RepID=B5JAZ3_9RHOB
          Length = 274

 Score =  190 bits (483), Expect = 4e-47,   Method: Composition-based stats.
 Identities = 62/266 (23%), Positives = 99/266 (37%), Gaps = 12/266 (4%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           +IL +TD HL       ++G++     Q  L+A      +   ++  GDL     +  Y 
Sbjct: 3   KILVLTDLHLRGAGK-TIIGLDPTARLQQALDAALGDHPDARALILMGDLTHSGRAEEYD 61

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV---FIGEQWQILLLDSQVF 132
              + +     P  ++ GNHD +    +A  +A ++P   V         +I+ LD+   
Sbjct: 62  KLRDLLHDCPIPVTYMLGNHDQRTRFCAAFPEATVTPQGHVQRIIDLAHHRIITLDTHDA 121

Query: 133 G---VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
                  G L   +L WL+  LA A  R  L+  HH P P G   +D  +L N  EL   
Sbjct: 122 AANPAHSGRLCAGRLAWLDAALAGAGGRMALVFAHHPPHPVGLPGMDAIALVNGDELLDR 181

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPH---CSNFTLDTIAPGWRTL 246
           L   P   +L CGH+H+ +     G       STC Q         +         +  L
Sbjct: 182 LRAAP--AHLFCGHVHRTISGQARGVAFTMFKSTCHQAPLDLLRPDSTLSIDEPAAYGLL 239

Query: 247 ELHADGTLTTEVHRLADTRFQPDTAS 272
            L   G +            + D  +
Sbjct: 240 LLTKGGVIAHSEDIALGLTPRSDLDA 265


>UniRef50_B6IT97 Phosphodiesterase, putative n=1 Tax=Rhodospirillum centenum SW
           RepID=B6IT97_RHOCS
          Length = 265

 Score =  189 bits (481), Expect = 8e-47,   Method: Composition-based stats.
 Identities = 74/263 (28%), Positives = 113/263 (42%), Gaps = 10/263 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + I Q+TD H+ A+   A   V+T ++    +  +       DL+V TGD+        Y
Sbjct: 1   MLIAQLTDLHVTARGARAFGEVDTNDALARAVAHVAALPRRPDLVVVTGDVVNGPQPGEY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGIS-----PAKRVFIGEQWQILLLDS 129
              AE +A    P + +PGNHD +  + +AL+             R+      +IL LD+
Sbjct: 61  AMAAELLAGLGLPLLVIPGNHDDREELRTALRPLDPGLPDGPYLHRMMDTGPLRILALDT 120

Query: 130 QVFGVPHGELSEFQLEWLERKLADAP-ERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
            V G P G L   +L W+  +LA+AP ER  L+L+HH P  +G   +D+ +   A  L  
Sbjct: 121 VVPGRPEGALDAPRLAWIADRLAEAPHERPLLVLMHHPPFVSGIGHMDRMNCAGADALAG 180

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCV--QFKPHCSNFTLDTIAPGWRTL 246
           +L     V  LLCGH+H+ +   W G      P+T           +    T  P    L
Sbjct: 181 LLRGRT-VAGLLCGHVHRPIAAHWRGIPCFCGPATAHLVALDLEPESPARWTREPPAVAL 239

Query: 247 ELHADGT-LTTEVHRLADTRFQP 268
            L  D   L T +  + D     
Sbjct: 240 HLWDDAHGLRTHLSFIGDFPPAR 262


>UniRef50_Q3AIR5 Possible ICC (3',5'-cyclic-nucleotide phosphodiesterase) protein
           n=4 Tax=Chroococcales RepID=Q3AIR5_SYNSC
          Length = 253

 Score =  188 bits (478), Expect = 2e-46,   Method: Composition-based stats.
 Identities = 74/256 (28%), Positives = 114/256 (44%), Gaps = 9/256 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +RILQ++D HL A     + G      ++  L+       +  L++ TGDL QD+S   Y
Sbjct: 1   MRILQLSDPHLVAADQGLVRGRPALAHFERALQLGGALNPD--LVLVTGDLCQDESWGGY 58

Query: 75  QHFAEGIAS-FRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFG 133
                 ++   R     LPGNHD    + + L     + A    + +  ++LLL S   G
Sbjct: 59  ARLRRALSQHVRCSVALLPGNHDHPLLLDAVLGRR-WTTAPADLLVQGVRVLLLSSHQVG 117

Query: 134 VPHGELSEFQLEWLERKLADAP--ERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
              G L   QL+WLE++L  +   +   ++ LHH P+  G + +D   L +   L+ +L 
Sbjct: 118 SAAGALGSLQLQWLEQRLRCSERLDLPLVVALHHPPIAIGDAGMDAIRLLDQACLEALLR 177

Query: 192 KFPHVKYLLCGHIHQELDLDWN---GRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLEL 248
               ++ +L GHIHQ     W+      LL  PST   FK            PG R +EL
Sbjct: 178 PHRALRAVLFGHIHQHWQGSWSTRPDVLLLGCPSTLCSFKAVQPCPLGRADDPGGRLVEL 237

Query: 249 HADGTLTTEVHRLADT 264
            ADG +   V R +  
Sbjct: 238 TADGAIQHRVLRWSSV 253


>UniRef50_Q5Z214 Putative phosphodiesterase n=1 Tax=Nocardia farcinica
           RepID=Q5Z214_NOCFA
          Length = 495

 Score =  188 bits (477), Expect = 2e-46,   Method: Composition-based stats.
 Identities = 65/260 (25%), Positives = 103/260 (39%), Gaps = 16/260 (6%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + + Q++DTH         LG    E  + V+  +    H  D I+ TGD+ +      Y
Sbjct: 2   ILVAQVSDTHFD-------LGARNNERVERVMAFLADLAHRPDAILVTGDVTESGKPEQY 54

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSAL--QDAGISPAKRVFIGEQWQILLLDSQVF 132
                 + +   P   +PGNHD + A  + L  +    SP   V       +++LD+ + 
Sbjct: 55  AEARVALQA-DIPVWAIPGNHDERAAFRTELLGEQPSDSPINHVHRVGALTVIMLDTTIP 113

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLL-LLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
           G P G + E    WL   LADAP    ++  +HH P       +D  +L     L  V+A
Sbjct: 114 GEPGGRIEEDTYRWLREVLADAPATGPIVLAMHHPPARLHSPIVDDIALAEPDRLADVVA 173

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTC----VQFKPHCSNFTLDTIA-PGWRTL 246
             P ++ +L GH H      + GR LL  PST       ++    +  +D    P     
Sbjct: 174 ADPRIRAVLTGHAHSAAATTFAGRPLLIAPSTASVLGGAWEVELPHRVMDYAPDPAVALH 233

Query: 247 ELHADGTLTTEVHRLADTRF 266
                G +TT    +    F
Sbjct: 234 VFDESGAMTTHFRTVPMGGF 253


>UniRef50_A9CKB5 Putative uncharacterized protein n=2 Tax=Alphaproteobacteria
           RepID=A9CKB5_AGRT5
          Length = 266

 Score =  187 bits (476), Expect = 3e-46,   Method: Composition-based stats.
 Identities = 62/245 (25%), Positives = 102/245 (41%), Gaps = 8/245 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++I+QITDTHL      A+ GV+     +A +  I     + DL+V TGDL       AY
Sbjct: 1   MKIIQITDTHLLPPG-IAINGVDPENQLRAAVADIVEKHADADLLVMTGDLCNYGEPEAY 59

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV---FIGEQWQILLLDSQV 131
           +   + +A    P   + GNHD +P   +A  +        +      E  ++L LDS  
Sbjct: 60  ELLRDILAPVSIPTRLMLGNHDRRPEFVAAFPEQPRDDNGYIQSFIDTEFGRLLFLDSHE 119

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
             V  G     +L WLE  L  A +    + +HH P+  G    +   + + G +   LA
Sbjct: 120 ADVIGGIYGADRLTWLENALESAGDLPITVFVHHPPMDCGIRHFEHIGMHDDGAIMRRLA 179

Query: 192 KFP-HVKYLLCGHIHQELDLDWN-GRRLLATPSTCVQFKPHCS--NFTLDTIAPGWRTLE 247
             P  +++++ GHIH  +      G    +  +   +F       +       P +R + 
Sbjct: 180 AHPAGIRHIVFGHIHVPMAGTTAEGIAYSSGQACAHRFITDIDVVDPLWTGGNPCYRVIS 239

Query: 248 LHADG 252
           L A G
Sbjct: 240 LGAFG 244


>UniRef50_Q8TVF8 Predicted calcineurin superfamily phosphohydrolase n=1
           Tax=Methanopyrus kandleri RepID=Q8TVF8_METKA
          Length = 270

 Score =  187 bits (476), Expect = 3e-46,   Method: Composition-based stats.
 Identities = 52/251 (20%), Positives = 102/251 (40%), Gaps = 17/251 (6%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           +I+ I+D H+            + E +   +E I   + +   ++ TGDL  +     Y+
Sbjct: 4   KIVHISDLHISP-----YRKSWSPEVFYRGIEQINDLRPDV--VIVTGDLTDNGLVREYE 56

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVP 135
             +  +    AP V +PGNHD +   +   +D      +   +     ++ LDS    V 
Sbjct: 57  EVSSLLEKIEAPVVPVPGNHDARNLGWMTFEDVFGDRYRVERVSADLYVVGLDSSEPDVD 116

Query: 136 HGELSEFQLEWLERKLADAPERH-TLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
           +G+L   + EWLE  L   P      + +HHH LP   +  +++ L +AGE+  +  K+ 
Sbjct: 117 YGQLGRERQEWLEETLRRIPGGACKCIAMHHHLLPVPGAGRERNVLVDAGEMINLCIKY- 175

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTL 254
            V  +LCGH H           ++   +         +          +  +E  ++ T+
Sbjct: 176 GVDLVLCGHRHVPFAAKVEDTVVVNAGT-------FSATKLRGYSRNSFNVIEF-SESTV 227

Query: 255 TTEVHRLADTR 265
           +  ++ +   R
Sbjct: 228 SVNLYEITTER 238


>UniRef50_A4AIJ2 Putative uncharacterized protein n=1 Tax=marine actinobacterium
           PHSC20C1 RepID=A4AIJ2_9ACTN
          Length = 305

 Score =  187 bits (475), Expect = 3e-46,   Method: Composition-based stats.
 Identities = 61/250 (24%), Positives = 102/250 (40%), Gaps = 9/250 (3%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           +L ++DTH  A        +++    + +   +       + IV TGDLA      AY+ 
Sbjct: 15  VLHLSDTHFLAGSGRLYDTLDSEAKLRQLFAELEASGSRPEAIVFTGDLADKGDEVAYRE 74

Query: 77  FAEGIA----SFRAPCVWLPGNHDFQPAMYSALQDAGI--SPAKRVFIGEQWQILLLDSQ 130
               +        A  VW+ GNHD +    + L D      P  RV      +I+ LDS 
Sbjct: 75  IRAIVEPAAERLGAHIVWVMGNHDDRRNFATTLLDEPASEQPIDRVTDINGLRIISLDST 134

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
           V G  HG +++ QL WL   LA      T+L +HH P+P+         LR+  EL  V+
Sbjct: 135 VPGQHHGHVTDAQLLWLHNVLATPAPHGTILAMHHPPVPSVLDLAVTVELRSQKELAAVI 194

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLD--TIAPGWRTLEL 248
            +   ++ ++ GH+H      + G  +    +TC     +           A  +  + +
Sbjct: 195 -RGSDIRSIIAGHLHYSTTATFAGIPVSVASATCYTQNLNVPVGGTRSQDGAQSFNLIHV 253

Query: 249 HADGTLTTEV 258
           + D  L + V
Sbjct: 254 YDDTVLHSVV 263


>UniRef50_A6U5M4 Metallophosphoesterase n=3 Tax=Rhizobiaceae RepID=A6U5M4_SINMW
          Length = 268

 Score =  187 bits (475), Expect = 4e-46,   Method: Composition-based stats.
 Identities = 47/254 (18%), Positives = 96/254 (37%), Gaps = 13/254 (5%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           +++  +D H+  +    ++G++        +  +     + DL++  GDLA      +Y+
Sbjct: 3   KLIIFSDLHMVPEG-GTIIGLDPHRRLANGIAHVNRFHADADLVIFAGDLAHAADRESYE 61

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDA---GISPAKRVFIGEQWQILLLDSQ-- 130
                +     P   + GNHD +        +A        ++       + +LLD+   
Sbjct: 62  RLQALLRELMPPAALMIGNHDRRELFLDVFAEAVTDANGFVQQAIDFPDCRAILLDTLFA 121

Query: 131 ----VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGEL 186
                     G L + +L WL+R+L +A +R  L+ +HH P  +G + +D   L N  E 
Sbjct: 122 PPYDYPVSHAGHLCQTRLAWLDRQLGEAGDRPALIFMHHPPHASGFAGMDMIRLVNEDEF 181

Query: 187 DTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFK---PHCSNFTLDTIAPGW 243
             ++ +  +V+++  GH+H+ +     G       S   Q                   +
Sbjct: 182 YALVKRHGNVRHIFAGHVHRTISGSSRGIPFSIFKSPVHQQPMPFATADASLSVDEPAAY 241

Query: 244 RTLELHADGTLTTE 257
               +  DG L   
Sbjct: 242 GIALVTPDGVLVHT 255


>UniRef50_UPI0001B53F99 metallophosphoesterase n=1 Tax=Streptomyces sp. AA4
           RepID=UPI0001B53F99
          Length = 253

 Score =  186 bits (474), Expect = 5e-46,   Method: Composition-based stats.
 Identities = 67/262 (25%), Positives = 99/262 (37%), Gaps = 22/262 (8%)

Query: 15  VR-ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
           +R    ++D HL   +              AV   +R  +   D + ATGDLA       
Sbjct: 1   MRVFAHLSDIHLDGSE-------RADARAAAVTRYLRNLEKPVDAVFATGDLADHGLPGE 53

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAG--ISPAKRVFIGEQWQILLLDSQV 131
           Y+  AE +     P V  PGNHD +     AL       +P        +  ++  DS +
Sbjct: 54  YRRAAELLD-LPVPVVVCPGNHDVRAPFREALLGEPASDAPVNTATKVAEVLLVSCDSTI 112

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
            G   G L++  L WL+  LA   +  + +  HH PL  G   +D         L  VL 
Sbjct: 113 PGKGAGYLADETLAWLDETLAAH-DGPSFVAFHHPPLDVGVPLVDAIRQTGEDRLAAVLK 171

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTC---------VQFKPHCSNFTLDTIAPG 242
           + P V  LLCGH+H     ++ G  +   P               +       LD ++P 
Sbjct: 172 RHPGVAALLCGHVHTGAATEFAGVPVRIAPGVVSGSLLPVEPGAGRGWDEGGPLDFVSPP 231

Query: 243 WRTLE-LHADGTLTTEVHRLAD 263
              L  LH DG LTT    + +
Sbjct: 232 SLLLHVLHDDGRLTTHQRAVTE 253


>UniRef50_B3Q702 Metallophosphoesterase n=5 Tax=Alphaproteobacteria
           RepID=B3Q702_RHOPT
          Length = 274

 Score =  186 bits (473), Expect = 7e-46,   Method: Composition-based stats.
 Identities = 56/252 (22%), Positives = 99/252 (39%), Gaps = 8/252 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++++ ++D HL       + G N   +++  L  I    H+ +L+V TGDL+    +  Y
Sbjct: 1   MKLIHLSDIHLTTPG-GTIGGRNPRLNFERALTHILRDHHDAELMVITGDLSDWGDAEDY 59

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQD--AGISPAKRVFIGEQWQILLLDSQVF 132
           +     + +F  P     GNHD +    S   +        + V      + LLLD+   
Sbjct: 60  RWLKAQLGAFPIPVRLCIGNHDRRENFLSVFPEFADDDGLVQGVCDTPAGRCLLLDTAEA 119

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
           G   G   E +  WL R+LA+ P    LL +HH+P+P     +DQ  L + G    ++ +
Sbjct: 120 GTHAGRYCETRRAWLTRQLAEHPG-PFLLFMHHNPMPTHLGPMDQIRLLDDGAFGQIVGR 178

Query: 193 F-PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFT---LDTIAPGWRTLEL 248
               ++++  GH H  L     G  + +   T     P  S         +   +  +  
Sbjct: 179 HRDRIRHIFFGHCHLPLAGSVAGVPVSSLRGTNHASYPLFSERRMLSASDLPESYGVVFF 238

Query: 249 HADGTLTTEVHR 260
             D      V  
Sbjct: 239 GDDYVTVHMVEF 250


>UniRef50_Q4JN56 Predicted 3',5'-cyclic-nucleotide phosphodiesterase n=1
           Tax=uncultured bacterium BAC13K9BAC RepID=Q4JN56_9BACT
          Length = 248

 Score =  186 bits (473), Expect = 7e-46,   Method: Composition-based stats.
 Identities = 66/250 (26%), Positives = 115/250 (46%), Gaps = 5/250 (2%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + ++QITD H+             +++    L+ I  H      +V TGDL+ D +  +Y
Sbjct: 1   MEMIQITDLHITKDIENIKNDCKPYQTLSTTLKHIEHHHSNVKDVVITGDLSNDYTRESY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
                 +  +++    LPGNHD      + + D  I+         +  +   D+ V G 
Sbjct: 61  MIIRNLLKKYQSTFYILPGNHDKLEH-INTICDEQITTNSIDLSMSKTLVYNFDTHVPGK 119

Query: 135 PHGELSEFQLEWLERKLADAPE-RHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKF 193
            +G L + Q+  L +KL    E    ++  HH  +  G  W+D+H   N+ EL  ++   
Sbjct: 120 TNGHLKKKQINELNKKLCINKEVDKVIIFTHHPIIKIGSEWIDEHISENSEELIQLMLSH 179

Query: 194 PHVKY-LLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDT-IAPGWRTLELHAD 251
              ++ +  GH+HQE +   N      TPSTC QFK     F L+T ++ G+R + LH +
Sbjct: 180 TDKEFKIFSGHVHQEFNCIKNNIEFFTTPSTCYQFKNQSEIFALETNLSYGYRVITLHDN 239

Query: 252 GTLTTEVHRL 261
            ++ T+V R+
Sbjct: 240 -SIRTKVLRI 248


>UniRef50_C0WNK1 3',5'-cyclic-nucleotide phosphodiesterase n=3 Tax=Lactobacillus
           RepID=C0WNK1_LACBU
          Length = 291

 Score =  185 bits (471), Expect = 1e-45,   Method: Composition-based stats.
 Identities = 54/246 (21%), Positives = 92/246 (37%), Gaps = 10/246 (4%)

Query: 14  RVRILQITDTHLFAQK--HEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
           + +I+QI+DTHL            ++  E  + V + I     + DLIV +GDL  +  +
Sbjct: 5   QCKIVQISDTHLTPAGAKPANHQHLDPEEKLRTVFDDIYNTNVDPDLIVISGDLIHEGDA 64

Query: 72  AAYQHFAEGIA----SFRAPCVWLPGNHDFQPAMYSALQDAGI--SPAKRVFIGEQWQIL 125
             Y  F   +        AP   + GNHD     Y          +        E  +  
Sbjct: 65  EVYADFHHMLDQEQERLMAPIKVILGNHDRTDQFYKGFLGKKRVATRCYYHESLEGLECY 124

Query: 126 LLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGE 185
            LD++   +  G L + QL WL+ +L +   R  ++ +HH         +    L+N  +
Sbjct: 125 FLDTKCGDIEQGYLDQTQLHWLKNQLQEYQ-RPGIIFMHHPLYGPPLQQMRYSILQNGDD 183

Query: 186 LDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRT 245
           L  V+    HVK +  GH+H       +G   +   ST         +    T    +  
Sbjct: 184 LLNVID-HTHVKAIFSGHVHFANSYVVDGILNVVADSTAYHINCANPHEHFVTDGTAYNV 242

Query: 246 LELHAD 251
           + +  D
Sbjct: 243 ITVDGD 248


>UniRef50_Q1GWA3 Metallophosphoesterase n=1 Tax=Sphingopyxis alaskensis
           RepID=Q1GWA3_SPHAL
          Length = 282

 Score =  185 bits (470), Expect = 1e-45,   Method: Composition-based stats.
 Identities = 56/248 (22%), Positives = 101/248 (40%), Gaps = 14/248 (5%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + I QITD H+              +    VL+ +    +  DL++ATGD+     + +Y
Sbjct: 1   MLIAQITDIHIGFDPDNPAEYN--RKRLDEVLDVLIEGPNRPDLLLATGDITDRGDADSY 58

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQ--DAGISPAKRVFIGEQWQILLLDSQVF 132
           +  A   +    P     GNHD +   ++     D G    +      + +++ +D+   
Sbjct: 59  RRLATAFSRCPFPVWPSVGNHDLRDNFHARFPGFDDGNGFVQYTVELPELRLVTIDTLEE 118

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNA-GELDTVLA 191
           G   G   E +  WL+ +LA AP R T +++HH P+ +G  W++ H           V+ 
Sbjct: 119 GRHGGAFCERRAAWLDAELAKAPARPTYIVMHHPPVESGIEWMNTHPDEPWVATFTDVVR 178

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHC---------SNFTLDTIAPG 242
           + P V+ L+CGH+H+ + + W GR +    ST  Q                  +    P 
Sbjct: 179 RHPQVRGLICGHLHRSVTVAWEGRTIAICSSTAPQVSLDLRPIDENHPDDRPMIVAEDPA 238

Query: 243 WRTLELHA 250
           +     + 
Sbjct: 239 YALHRWNG 246


>UniRef50_C9RR52 Metallophosphoesterase n=1 Tax=Fibrobacter succinogenes subsp.
           succinogenes S85 RepID=C9RR52_FIBSS
          Length = 249

 Score =  185 bits (470), Expect = 2e-45,   Method: Composition-based stats.
 Identities = 69/254 (27%), Positives = 118/254 (46%), Gaps = 14/254 (5%)

Query: 11  GEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQS 70
            +  ++I QI+D H+       +  ++  +++            + DL+V +GDLA + S
Sbjct: 2   EKKVLKIGQISDAHIG-DDDRLVQDIDVRKNFLTA--YNSESMKDLDLLVLSGDLADNAS 58

Query: 71  SAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQ---DAGISPAKRVFIGEQWQILLL 127
           + AY   A  I   + P   +PGNHD    M                  +  +   I  L
Sbjct: 59  TDAYSFIAGVIKDSKVPVCIIPGNHDNLEVMEKVFDLKDKVHNGKCYYRYDLDGRSIFFL 118

Query: 128 DSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLD-QHSLRNAGEL 186
           DS       G +S  QL WLE++ A   +   LL LHH P   G  ++D ++S++N  E+
Sbjct: 119 DSA-----DGTVSSDQLSWLEQETAKI-DGEVLLFLHHPPCLCGHKFMDLRYSMKNIAEV 172

Query: 187 DTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTL 246
              L+K  ++K++  GH H E+ +    + +  TPST +Q  P+ + F L + AP WR +
Sbjct: 173 QATLSKIKNLKHIFVGHYHSEMTIQLEDKTVYVTPSTQMQIDPNITVFCLSSAAPRWRLI 232

Query: 247 ELHADGTLTTEVHR 260
           E   +  + T+V+ 
Sbjct: 233 E-WGENFMETKVYF 245


>UniRef50_C9CTH4 Phosphodiesterase n=6 Tax=Proteobacteria RepID=C9CTH4_9RHOB
          Length = 284

 Score =  184 bits (468), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 57/266 (21%), Positives = 96/266 (36%), Gaps = 11/266 (4%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++ + +TDTH+       L G N        +++I     + D  V TGDL     + AY
Sbjct: 1   MKFIHLTDTHVIG-GDRTLYGANPARRLALAVDSINAEHGDADFTVVTGDLTHWGDADAY 59

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV---FIGEQWQILLLDSQV 131
             F   I     P V + GNHD   A      +        V       Q   L LD++ 
Sbjct: 60  AAFEAQIRRLSMPLVLMVGNHDDTAAFARCFPEVARDEHGFVQSRRETSQGSCLFLDTKA 119

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
            G   G     +L WL ++L ++      L +HH P   G S +D   + +      V+ 
Sbjct: 120 PGTHAGGYCAQRLGWLRQQLDESSG-PVFLFMHHPPFRHGISSMDAIMMLDHHAFWRVIE 178

Query: 192 KF-PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFK----PHCSNFTLDTIAPGWRTL 246
                +++L  GH+H+ +  +W G           Q              D   P +  +
Sbjct: 179 PHRARIRHLFFGHVHRAIFGNWRGISYSCMRGLNHQVTLDLGTDADTIDGDFAEPAYGVV 238

Query: 247 ELHADGTLTTEVHRLADTRFQPDTAS 272
            L  +  +T  +H  A+   +    +
Sbjct: 239 -LADEDCVTVHLHEFANRTPRFSLHA 263


>UniRef50_B7BFD3 Putative uncharacterized protein n=1 Tax=Parabacteroides johnsonii
           DSM 18315 RepID=B7BFD3_9PORP
          Length = 238

 Score =  184 bits (468), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 53/244 (21%), Positives = 102/244 (41%), Gaps = 8/244 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +RI+ I+D HL       +   +T   +   ++ I+      D I+ +GDL+ D S+ +Y
Sbjct: 1   MRIIHISDIHLENHG-LPIWNTDTKLHFDKAIKKIQTMD-NIDAIIISGDLSNDGSAWSY 58

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
            +    +A    P    PGNHD     Y +   +       +F+   W  ++L+S + G 
Sbjct: 59  NYIDNLLAKTNIPTFCCPGNHDNLDIFYGS-HKSWFYKNCELFMLNGWTFIMLNSVMAGK 117

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
             G       ++L+  L       T+++LHH P+     WL++  L N    + ++ K+ 
Sbjct: 118 SRGNFYPD--KFLD--LLKHSCGPTVIVLHHPPIEQD-GWLNRKLLENRDVFNDIIHKYK 172

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTL 254
           +++ +L GH H       +G    +  S    F P    F +     G+  + L+    +
Sbjct: 173 NIRLVLYGHTHHHEIKTIDGIIYSSASSIGFAFHPKLLKFQIAHGREGFSLITLNDSNII 232

Query: 255 TTEV 258
              +
Sbjct: 233 IENI 236


>UniRef50_Q2J3S6 Metallophosphoesterase n=5 Tax=Rhodopseudomonas palustris
           RepID=Q2J3S6_RHOP2
          Length = 274

 Score =  183 bits (465), Expect = 6e-45,   Method: Composition-based stats.
 Identities = 63/260 (24%), Positives = 102/260 (39%), Gaps = 10/260 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++ + +TDTH  A+    + G++  E  +A +  I     E   ++ TGDLA     AAY
Sbjct: 1   MKFVVLTDTHFVARGRR-IYGLDPAERLRAAIGCINRDHPEIAFVIVTGDLAHWGEDAAY 59

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV---FIGEQWQILLLDSQV 131
           +  AE +   RA  + L GNHD +                 V    + +   ++ LD+  
Sbjct: 60  EALAEVLGELRALTILLMGNHDKRDGFARYFPGVPRDADGFVQTMQVFDAATVVTLDTLN 119

Query: 132 FGV--PHGELSEFQLEWLERKLADAP-ERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
                  G L + +L +LE  L  AP +R  LL  HH P   G  ++D   L N      
Sbjct: 120 EAAPNHEGLLCDARLAFLEHALTSAPTDRPLLLFQHHPPFDTGLRYMDTIRLANPEAEWE 179

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPH---CSNFTLDTIAPGWRT 245
           V+A+     YL  GH+H+ +   W G       +   Q         +      AP +  
Sbjct: 180 VIARTRRPDYLFMGHLHRPIAGVWRGIPFHIQRALAHQVAFDLVTEGHIPGSHEAPDYAH 239

Query: 246 LELHADGTLTTEVHRLADTR 265
           + +  D  +  +   L D  
Sbjct: 240 VSVEGDRIVIHQRSFLYDGP 259


>UniRef50_C7D8R5 Phosphodiesterase n=1 Tax=Thalassiobium sp. R2A62
           RepID=C7D8R5_9RHOB
          Length = 292

 Score =  183 bits (465), Expect = 6e-45,   Method: Composition-based stats.
 Identities = 55/243 (22%), Positives = 90/243 (37%), Gaps = 9/243 (3%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           + L  TD H+     E ++ ++        L     H  +   ++  GDL      + Y 
Sbjct: 27  KYLIFTDVHIVGAG-ETIIDLDPAVRLTQGLAHAVHHHPDAKAVIIAGDLTHHGLPSEYT 85

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGI--SPAKRVFIGEQWQILLLDS---Q 130
             AE +     P   + GNHD++P+       A       +         IL LD+    
Sbjct: 86  RLAEVLDECPLPVHVMLGNHDYRPSFRKVFTQAPDVDGFVQFAIHDGDHVILCLDTKDQT 145

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
                 G L E +L+WL   L    ++   L+ HH     G + +D+  L N  E   ++
Sbjct: 146 APDHHSGLLCETRLDWLAAHLETHADKQVTLIAHHPAFDTGFTGMDRIKLHNGAEFRDLI 205

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFK---PHCSNFTLDTIAPGWRTLE 247
           A+ P VK L+ GH+H+ +    NG  +    STC Q                   +  L 
Sbjct: 206 AQHPCVKQLIHGHVHRTIMGQTNGVAVAMLKSTCHQIPMCLGDDDTSLAVDEPGAYGVLL 265

Query: 248 LHA 250
           L+ 
Sbjct: 266 LNE 268


>UniRef50_A3W656 Ser/Thr protein phosphatase family protein n=3 Tax=Rhodobacteraceae
           RepID=A3W656_9RHOB
          Length = 265

 Score =  183 bits (464), Expect = 7e-45,   Method: Composition-based stats.
 Identities = 57/263 (21%), Positives = 99/263 (37%), Gaps = 10/263 (3%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQH---EFDLIVATGDLAQDQSSA 72
           R L ++D H+  +       ++T    +  ++ +          D ++ TGD++ D S+ 
Sbjct: 3   RFLHLSDLHVVPEGQLVSGQLDTARLLRLAIDTLTTRLDAIGPVDAVLVTGDISDDGSTE 62

Query: 73  AYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQD----AGISPAKRVFIGEQWQILLLD 128
           +Y+     +       + +PGNHD +    +A  D            +      +++ LD
Sbjct: 63  SYEIARRDLMRLGHRLLVVPGNHDGRETFRAAFSDLPEMRPTGLIDWIADIGDTRVIGLD 122

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           + + G   G L +  L  L   L+ A  R TL+ LHH PL  G  ++D   L N   L  
Sbjct: 123 TLIEGKGGGVLRDESLALLSEALSTAGGRQTLVALHHPPLRTGLRFMDAIGLENPNALRI 182

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDT---IAPGWRT 245
           VL +      +L GH+H           ++  PS C  F                 G   
Sbjct: 183 VLDQHDAPVRVLAGHVHGVYHGLLGRHPVVTAPSCCSAFALDLREDAPVGFMTGPTGCAL 242

Query: 246 LELHADGTLTTEVHRLADTRFQP 268
           ++  A G  T    R  +  F+ 
Sbjct: 243 IDTGAGGVWTELPLRHGEGPFRF 265


>UniRef50_A5CN72 Putative 3',5'-cyclic-nucleotide phosphodiesterase n=2
           Tax=Clavibacter michiganensis RepID=A5CN72_CLAM3
          Length = 301

 Score =  183 bits (464), Expect = 8e-45,   Method: Composition-based stats.
 Identities = 72/270 (26%), Positives = 116/270 (42%), Gaps = 26/270 (9%)

Query: 12  EARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
              +R++ ++DTHL          V+T  + + VL        E  L+V +GDL++D ++
Sbjct: 6   PGSLRLVHLSDTHLLRDGGLHQGVVDTGAALERVLVEA-DRVPEVRLLVGSGDLSEDGTA 64

Query: 72  AAYQHFAEGIASF----RAPCVWLPGNHDFQPAMYSALQDAGI-------------SPAK 114
            +Y    E +  +     A  V  PGNHD + A    L D                 P  
Sbjct: 65  ESYALLRERLVPWTSSRGAALVLTPGNHDVRSAFRLVLGDGHGAPGTDDGRDPAAVPPVD 124

Query: 115 RVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSW 174
            V I + W+I  LD+ V G  +G L E QL+ L   LA   E  T+L+LHH P+PA  + 
Sbjct: 125 GVTIVDGWRIATLDTSVPGKGYGALREQQLDGLRELLATPAEHGTVLVLHHPPVPAPTTL 184

Query: 175 LDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTC----VQFKPH 230
            +  +L+    L  ++ +   V+ +L GH H  +     G  +L  P       V  +P 
Sbjct: 185 HESLALQGPERLAEIV-RGSDVRVILSGHYHHHIVGSLAGVPVLVAPGVANETDVAAEPG 243

Query: 231 CSNFTLDTIAPGWRTLELHADGTLTTEVHR 260
                      G+  +++  DG +T+ V R
Sbjct: 244 TERIVRG---SGFLVVDVRPDGRVTSVVVR 270


>UniRef50_A9DF72 Possible 3',5'-cyclic-nucleotide phosphodiesterase, cpdA n=1
           Tax=Hoeflea phototrophica DFL-43 RepID=A9DF72_9RHIZ
          Length = 278

 Score =  183 bits (464), Expect = 8e-45,   Method: Composition-based stats.
 Identities = 61/268 (22%), Positives = 103/268 (38%), Gaps = 19/268 (7%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++++ I+D HL       +LG++   +++  L  +  H  + + IV TGDL       +Y
Sbjct: 1   MKLVHISDIHL---NEAPILGLDPVANFKRCLAYVEAHDADAERIVITGDLTHHGGEESY 57

Query: 75  QHFAEGIASFR-----APCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQW---QILL 126
           +   + +A+       AP   L GNHD +    S        P   V   E+      + 
Sbjct: 58  RLLVDILAASPLQDKLAP-RLLIGNHDHRETFASVFSSTHRDPNGFVQWTEETPAGVFVY 116

Query: 127 LDSQVFGVPHGELSEFQLEWLERKL--ADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAG 184
           +D+   G   G   E ++ WL   L  A +      L +HH+P+    +  D   + N  
Sbjct: 117 MDTVDQGRHGGRYCEARMAWLAGVLDDARSSGARAFLFMHHNPVRVNVANADIIGIINER 176

Query: 185 ELDTVLAKFPHV-KYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFT----LDTI 239
           EL  +L ++  V  ++  GH H  L     G    A  ST     P  S          +
Sbjct: 177 ELQALLKRYNDVIAHMFFGHCHYSLSGSVAGISYSAPRSTNHPCWPDFSGMANRMGFGEL 236

Query: 240 APGWRTLELHADGTLTTEVHRLADTRFQ 267
           AP +    L  D  +   +  L   + Q
Sbjct: 237 APNYNVCFLRDDSIVVHTIDFLDAEKVQ 264


>UniRef50_C9AD97 Phosphoesterase n=3 Tax=Enterococcus casseliflavus
           RepID=C9AD97_ENTCA
          Length = 270

 Score =  182 bits (463), Expect = 9e-45,   Method: Composition-based stats.
 Identities = 55/258 (21%), Positives = 90/258 (34%), Gaps = 21/258 (8%)

Query: 15  VRILQITDTHLFAQKHEALLGV--------NTWESYQAVLEAIRPHQHEFDLIVATGDLA 66
           + +L I+D H          G         N     +  ++  +      DL+V +GDL 
Sbjct: 1   MNVLHISDIHFRESYLPCEEGYQGMLAAMQNPLIPLEECIQDAKARA-AIDLVVISGDLT 59

Query: 67  QDQSSAAYQHFAEGIASF--RAPCVWLPGNHDFQPAMYSALQD-----AGISPAKRVFIG 119
           +D + A Y    + +       P V   GNHD +       Q      A  +P  +V+  
Sbjct: 60  EDGAPADYASLKQYLEKAFGSVPIVVTLGNHDIKRHFRQGWQGKSVETASDTPFNQVYET 119

Query: 120 EQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHS 179
           E   I+  D+  +G   G + E Q EWL+  LA   E+  + + HHH LP         +
Sbjct: 120 ETLAIVTFDNSCYGYADGIVDERQFEWLQATLAQLKEKKIVFVTHHHLLP---DQASTPA 176

Query: 180 LRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTI 239
              A  L  +L ++  +  +L GH H        G       S     +           
Sbjct: 177 WAGANRLVALLQQY-QISCILSGHTHHAFTGTIAGIPYYTVASMSFVGEDEGDGMVRFEE 235

Query: 240 APGWRTLELHADGTLTTE 257
             G+       +G L  +
Sbjct: 236 RYGYNLYRF-EEGALVHQ 252


>UniRef50_Q2RNL1 Metallophosphoesterase n=1 Tax=Rhodospirillum rubrum ATCC 11170
           RepID=Q2RNL1_RHORT
          Length = 283

 Score =  182 bits (462), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 72/271 (26%), Positives = 109/271 (40%), Gaps = 21/271 (7%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + I Q +D H+          V+T  + +A +  ++   H  DL++ TGDL Q      Y
Sbjct: 1   MLIAQTSDLHIRPPGMLVGGVVDTAAALEACVAHLQALAHRPDLLLITGDLTQQGRPEEY 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKR------------VFIGEQW 122
            H    +A    P +  PGNHD + A+ + L      P                F     
Sbjct: 61  AHLRRLLAPLDLPLLVCPGNHDDRAALRAGLDGLCPWPEPPGAGIPDGATLDLTFDLGPL 120

Query: 123 QILLLDSQVFGVPHGELSEFQLEWLERKLADAP--ERHTLLLLHHHPLPAGCSWLDQHSL 180
           +++ LDS   G   G LS  Q  WL+  L++A   ++  +L LHH P P G   LD   L
Sbjct: 121 RLIGLDSLRSGHSGGALSASQEAWLDSALSEAAFLDKPVVLFLHHPPFPMGIDHLDAARL 180

Query: 181 RNAGELDTVLAKFPH-VKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSN--FTLD 237
             +  L  +L + P  V  LLCGH H+ +   W+G  +   P+    F    ++      
Sbjct: 181 DQSETLGLLLDRHPGRVVRLLCGHAHRHVTTVWHGVAVTVCPAPAFAFALDFAHKAPAAI 240

Query: 238 TIAPGWRTLELHADGT---LTTEVHRLADTR 265
           T+ P    L    DG    L T V  +    
Sbjct: 241 TLEPPALLLHRW-DGRARLLVTHVSPIGAGE 270


>UniRef50_Q47WJ3 Cyclic AMP phosphodiesterase n=1 Tax=Colwellia psychrerythraea 34H
           RepID=Q47WJ3_COLP3
          Length = 263

 Score =  181 bits (461), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 75/261 (28%), Positives = 118/261 (45%), Gaps = 15/261 (5%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
                +   QITD+HLF+       G N   + + VL +I         I+ TGDL QD 
Sbjct: 9   PNNQPITFAQITDSHLFSSVDGLHHGHNVLANLKKVLLSICD-NPSIKYIIFTGDLTQDH 67

Query: 70  SSAAYQHFAEGIASFRA--PCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLL 127
           +  +YQ+F + +       P  +L GNHD    +      +    A +      WQ+ L+
Sbjct: 68  TEQSYQNFVDCVLECHITVPIYYLAGNHDEPKLLDKYFSASPF-QADKEINLSHWQVQLV 126

Query: 128 DSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELD 187
           DS+    P G + E  L  L+  +     +  LL++HHHP+  G  ++D+H L+N     
Sbjct: 127 DSKSA-TPAGYVGEQALVKLKDAIQKNKNQ--LLMMHHHPIDVGY-FIDKHGLQNKDAFW 182

Query: 188 TVLAKFPHVKYLLCGHIHQELDLDWN-------GRRLLATPSTCVQFKPHCSNFTLDTIA 240
            V+  + ++K + CGH+H ++ L             L   P+T +QF P        +  
Sbjct: 183 QVINSYDNIKAIACGHVHGDMTLTNAITSPINEPVVLYTCPATSIQFDPTVDGVAALSKG 242

Query: 241 PGWRTLELHADGTLTTEVHRL 261
           PG+R   L+ADG L TEV  L
Sbjct: 243 PGYRLFSLYADGQLNTEVVML 263


>UniRef50_A5UK60 Predicted phosphohydrolase, calcineurin-like superfamily n=2
           Tax=Methanobrevibacter smithii RepID=A5UK60_METS3
          Length = 247

 Score =  181 bits (459), Expect = 3e-44,   Method: Composition-based stats.
 Identities = 52/252 (20%), Positives = 101/252 (40%), Gaps = 20/252 (7%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           I+ I+D H+     E        + +   +  I     +   I+ TGDL  +   + +  
Sbjct: 4   IVHISDLHISELGFE-------EDVFIKAVAEINAINPDM--IILTGDLTNNGYYSEFIQ 54

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPH 136
             + +  F AP   +PGNHD +   Y   ++     + ++   +++ ++ LDS    +  
Sbjct: 55  ATKYLEMFDAPLFAVPGNHDARNLGYETFEELIGECSWKLTKDDEFVVIGLDSSSPDISS 114

Query: 137 GELSEFQLEWLERKLADA--PERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
           G +   Q  W+E +L      E  +++ LHHH +P   +  +++ L +AG++   L    
Sbjct: 115 GNVGRPQHLWMEHQLDQCVIEELFSIVALHHHVIPIPKTGRERNVLTDAGDVLKTLTDHE 174

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTL 254
            V  +L GH H       N    +   S         SN         +   E+  D T+
Sbjct: 175 -VDLVLAGHKHVPNIWKMNNTLFVNAGSLS-------SNKLRGDDKNSYNVYEITED-TI 225

Query: 255 TTEVHRLADTRF 266
              ++++   RF
Sbjct: 226 RIFLNKVDGERF 237


>UniRef50_C5CDX7 Metallophosphoesterase n=1 Tax=Kosmotoga olearia TBF 19.5.1
           RepID=C5CDX7_KOSOT
          Length = 358

 Score =  181 bits (459), Expect = 3e-44,   Method: Composition-based stats.
 Identities = 51/265 (19%), Positives = 97/265 (36%), Gaps = 30/265 (11%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
                     + D              N+  ++  ++E I     E   +V TGD+  D 
Sbjct: 48  THSGNFSFAVLGD------------NKNSISTFGKIIEQINT-NPEITFVVNTGDMVFDG 94

Query: 70  SSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDS 129
           S   Y  F + ++  + P + +PGNHD      +   +    P    F  +Q   ++LDS
Sbjct: 95  SVTKYNFFLKQLSKLQKPFIPVPGNHDIADGGMNNYVE-FFGPLYYAFAVDQVYFIVLDS 153

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQ------HSLRNA 183
                    +  +Q++WLE +L ++ +     +  H P+      +D+       + +NA
Sbjct: 154 S----NEETIGAWQMKWLEEQLKNSQKHKYRFVFLHVPIFDPRLPMDKQPGHSLKNTKNA 209

Query: 184 GELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGW 243
            EL  +L K+ +V  +  GHIH     +W G   + T                +     +
Sbjct: 210 MELLKLLQKY-NVTMVFAGHIHGYFRGEWEGVPYIVTGGAG----AELVGLNKEHYFYHY 264

Query: 244 RTLELHADGTLTTEVHRLADTRFQP 268
             + +   G +  EV ++    F  
Sbjct: 265 LIVRVKDTG-IDYEVVKVNSPDFNV 288


>UniRef50_C6VLV6 3',5'-cyclic-nucleotide phosphodiesterase n=3 Tax=Lactobacillus
           plantarum RepID=C6VLV6_LACPJ
          Length = 290

 Score =  180 bits (458), Expect = 4e-44,   Method: Composition-based stats.
 Identities = 62/265 (23%), Positives = 99/265 (37%), Gaps = 10/265 (3%)

Query: 13  ARVRILQITDTHLFAQKHEALLG--VNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQS 70
             ++++QI+D HL       + G   + W     +++ IR      DLIV TGDL  D S
Sbjct: 8   RPLQVIQISDLHLTPHGQVPVHGQQYDPWGKLANIIDDIRRLPTMPDLIVFTGDLIHDGS 67

Query: 71  SAAYQHFAEGI----ASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVF-IGEQWQIL 125
           +  YQ     +    A F      + GNHD + A Y     A   P              
Sbjct: 68  ADDYQRLHAIVHTMEAEFDCHVRVILGNHDRRAAFYEGYLPADPGPYYASRMRIGNNDFY 127

Query: 126 LLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGE 185
            LDS+V G   G L+  QL+WL + L  AP +   L LHH       + +    L+N   
Sbjct: 128 FLDSKVSGYEAGWLAPQQLQWLGKHLRQAPTKRAFLFLHHPLDGPTMTNMHYAILQNTPA 187

Query: 186 LDTVLAKFPHVKYLLCGHIHQELDLDW-NGRRLLATPSTCVQFKPHCSNFTLDTIAPGWR 244
           L +VL    ++  +  GH+H        +    +   S       H  +         ++
Sbjct: 188 LLSVLRGH-NLGGVFSGHVHFVSSYLIGDNILNVVAGSAAYAIDCHDLHHHYVHEGSSYQ 246

Query: 245 TLELHADGTLTTEVHRLADTRFQPD 269
            + +   G +     +L   +   D
Sbjct: 247 IITIDR-GQVGVTTRQLLHGKAVID 270


>UniRef50_A5GLK1 Predicted phosphohydrolase n=4 Tax=Synechococcus RepID=A5GLK1_SYNPW
          Length = 265

 Score =  179 bits (455), Expect = 7e-44,   Method: Composition-based stats.
 Identities = 70/260 (26%), Positives = 114/260 (43%), Gaps = 15/260 (5%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           R++Q++D HL A+    + G +    +Q  L      Q +  L++ TGD   D++   Y 
Sbjct: 3   RLIQLSDPHLVARAEGRVRGRSALSLFQKALAQALQEQPD--LLLVTGDCCHDETWCGYV 60

Query: 76  HFAEGIASF----RAPCVWL---PGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLD 128
              + + +      A  V L    GNHD    + + L    +     V     W++L++ 
Sbjct: 61  RLRDAVDAAIQQQAARTVCLGFTAGNHDHPQRLRAVLGRHWVVAPG-VMDAGCWRLLVVS 119

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAP--ERHTLLLLHHHPLPAGCSWLDQHSLRNAGEL 186
           S   G   G +   QL WL  +L +A    +  ++ LHH P+P G + +D   L +  +L
Sbjct: 120 SHRAGGCAGVIGGVQLSWLNTQLREAETLGKFVVVALHHPPVPIGDASMDTIGLSDGEQL 179

Query: 187 DTVLAKFPHVKYLLCGHIHQELDL---DWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGW 243
              L ++P V+ +L GHIHQ         +   LL  PST V F P           PG 
Sbjct: 180 MDSLKRWPAVRVVLFGHIHQHWKGMAAPRSDLSLLGCPSTLVSFHPVQPCPLGRAWDPGG 239

Query: 244 RTLELHADGTLTTEVHRLAD 263
           R L+L  DG++   + R + 
Sbjct: 240 RLLDLMEDGSVQERLMRWSA 259


>UniRef50_C8XD18 Metallophosphoesterase n=1 Tax=Nakamurella multipartita DSM 44233
           RepID=C8XD18_NAKMY
          Length = 292

 Score =  179 bits (455), Expect = 7e-44,   Method: Composition-based stats.
 Identities = 61/270 (22%), Positives = 104/270 (38%), Gaps = 9/270 (3%)

Query: 12  EARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIR---PHQHEFDLIVATGDLAQD 68
                +  ++D+HL +        ++   +    +  +R         D ++ +GDL   
Sbjct: 13  RPTHVLAHLSDSHLTSAGVRYNQVLDADAALDRAVAVLRSAVADGRPLDAVILSGDLTDT 72

Query: 69  QSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGI-SPAKRVFIGEQWQILLL 127
               AY+     +     P ++  GNHD +   + +L   G   P  +       ++L L
Sbjct: 73  GDPDAYRRLRAAVEPLGVPVLYATGNHDVRTEFHRSLLGRGDEGPVLQSVQVGGLRMLAL 132

Query: 128 DSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAG--E 185
           DS + G  HG L+   L  L   LAD     T+++LHH PLP     L   +L  A    
Sbjct: 133 DSTIPGAGHGRLTAEHLAELTAALADPAPEGTIVVLHHAPLPPPSPLLSYFALEAASRIA 192

Query: 186 LDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPG-WR 244
           L   +A    V+ +L GH H           +    ST ++  P   N    T A G + 
Sbjct: 193 LRDAIAG-TDVRLVLAGHHHLAQSGTLGAIPVAVAGSTAIRTDPLAPNGHERTWASGSFN 251

Query: 245 TLELHADGTLTTEVHRLADTRFQPDTASEG 274
            ++++ D T+T  V  +       D  + G
Sbjct: 252 LVQVYPD-TITVSVIPVDGAAPVFDLDAAG 280


>UniRef50_A5V3T9 Metallophosphoesterase n=2 Tax=Sphingomonadaceae RepID=A5V3T9_SPHWW
          Length = 289

 Score =  179 bits (455), Expect = 9e-44,   Method: Composition-based stats.
 Identities = 59/255 (23%), Positives = 94/255 (36%), Gaps = 15/255 (5%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + I Q+TD H+             +    A ++ +       D +  TGDL      A+Y
Sbjct: 1   MLIAQLTDLHIGFDLENP--DELNFHRVAAAIDYVMGLSVVPDRLFLTGDLTDHGDVASY 58

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAG--ISPAKRVFIGEQWQILLLDSQVF 132
           +     I     P     GNHD + AM     D        + V    + +I++LD+   
Sbjct: 59  ERLKGLIDGCGFPVHLCVGNHDDRAAMKQVFPDLPVEDGFVQYVIDEPEVRIIVLDTLDP 118

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT-VLA 191
           G   G     +  WL+ +LA+ P +  L++LHH P+  G  W+  H       +    + 
Sbjct: 119 GHHGGAFGHRRAGWLKARLAEVPGKPVLIVLHHPPIETGIPWMTAHQTEPWVVMLDKAIG 178

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCS---------NFTLDTIAPG 242
             P V  +  GHIH+ +   W GR L   PST  Q     +            +    PG
Sbjct: 179 DRPGVTMI-SGHIHRSITTSWRGRMLAVAPSTAPQVALEMAPIDPERPDERPMIVAEQPG 237

Query: 243 WRTLELHADGTLTTE 257
                   +G +T  
Sbjct: 238 VALHLWTGEGFVTHH 252


>UniRef50_B5K790 Metallophosphoesterase n=1 Tax=Octadecabacter antarcticus 238
           RepID=B5K790_9RHOB
          Length = 265

 Score =  178 bits (453), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 54/242 (22%), Positives = 87/242 (35%), Gaps = 12/242 (4%)

Query: 24  HLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIAS 83
           HL       ++G++     Q  L+       +   ++  GDL     +  Y    + +  
Sbjct: 2   HLRGAGK-TIIGLDPTVRLQQSLDTALRDHPDAKALILMGDLTHSGRAEEYDILRDMLQD 60

Query: 84  FRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV---FIGEQWQILLLDSQVFG---VPHG 137
              P  ++ GNHD +    +    A ++P   V         +I+ LD+          G
Sbjct: 61  CPIPVTYMLGNHDQRAPFRATFPTAPVTPQGHVQRIVDLPHHRIITLDTHDAAANPAHSG 120

Query: 138 ELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVK 197
            L   +L WL+  LA A  R  L+  HH P   G   +D  +LRN  +L   L   P   
Sbjct: 121 LLCADRLAWLDAALAGAGGRMALVFAHHPPHAVGLPGMDAIALRNGDDLLDRLRATP--A 178

Query: 198 YLLCGHIHQELDLDWNGRRLLATPSTCVQFKPH---CSNFTLDTIAPGWRTLELHADGTL 254
           +L CGH+H+ +     G       STC Q         +         +  L L   G +
Sbjct: 179 HLFCGHVHRTISGQTRGVAFTMFKSTCHQAPLDLIRPDSTLSIAEPAAYGLLLLSEGGVI 238

Query: 255 TT 256
             
Sbjct: 239 AH 240


>UniRef50_B5JMC7 Ser/Thr protein phosphatase family protein n=1 Tax=Verrucomicrobiae
           bacterium DG1235 RepID=B5JMC7_9BACT
          Length = 309

 Score =  178 bits (452), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 55/286 (19%), Positives = 101/286 (35%), Gaps = 49/286 (17%)

Query: 12  EARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ-- 69
           +  +RI  +TD H+   K       +  E     ++  +    + DLI+  GD   D   
Sbjct: 30  KRSLRIAHLTDIHVMPDK-------DAPEKMARAIQHAQSQTDKPDLILNGGDCIMDALK 82

Query: 70  -----SSAAYQHFAEGIA-SFRAPCVWLPGNHDFQPAMYS------------ALQDAGIS 111
                + A +  +   +      P     GNHD                   A+++  + 
Sbjct: 83  RSKSETKAQWSEWHGVLKNELELPFYSAIGNHDIWGWALPNSKKNVSYGKQWAMEELALK 142

Query: 112 PAKRVFIGEQWQILLLDSQ--VFGVPHGE---LSEFQLEWLERKLADAPERHTLLLLHHH 166
                F    WQ ++LDS         G    L E Q  WL + LA++  +  + +L H 
Sbjct: 143 QRYYSFEKNNWQFIVLDSSHFEPSFKSGYTAKLDEAQFAWLAQTLAESDPKKPICILSHI 202

Query: 167 PLPAGCSWLDQHSLR-------------NAGELDTVLAKFPHVKYLLCGHIHQELDLDWN 213
           P+ + C + D  + +             +A  +  + A+ P+VK  L GHIH    + + 
Sbjct: 203 PIISFCPFFDGDNEKSGDWQVPGPWMHIDARRIKDLFAQHPNVKLALSGHIHLRDQVRYL 262

Query: 214 GRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTEVH 259
           G   L   +    +               +  ++L+ DGT  ++  
Sbjct: 263 GIDYLCNGAVSGGWWDGPYQ----EFPSAYVLVDLYEDGTSQSQYV 304


>UniRef50_Q28NL1 Metallophosphoesterase n=2 Tax=Rhodobacteraceae RepID=Q28NL1_JANSC
          Length = 277

 Score =  178 bits (452), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 64/257 (24%), Positives = 97/257 (37%), Gaps = 18/257 (7%)

Query: 18  LQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHF 77
           L  TD H+     E ++G++    +Q  L        +   IV  GDL      A Y   
Sbjct: 9   LIFTDLHITPPG-ETIIGLDPLARFQEGLAHALSRHPDAQHIVLLGDLTHTGDPAEYARL 67

Query: 78  AEGIASFRAPCVWLPGNHDFQPAMYSALQDA--GISPAKRVFIGEQWQILLLDSQVFG-- 133
              +A    P     GNHD +  + +A   A      A+        ++L+LD+  +   
Sbjct: 68  VPALADCPIPLTVTMGNHDLRDHLRNAFPTALNPDGFAQTARDLGPLRLLILDTHDYDNQ 127

Query: 134 ---VPHGELSEFQLEWLERKLADAPE--RHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
                 G L E +L WL+ +LA A +  +  ++  HH P P G   +D   L NA  L +
Sbjct: 128 APLEQDGWLCETRLAWLDAELARAADDGKDVVVFAHHPPCPVGFWAMDAIGLANADALLS 187

Query: 189 VLAKFPHVKYLLCGHIHQELDLDW-----NGRRLLATPSTCVQFKPHCSNFTL---DTIA 240
            L   PHVK+L+CGHIH+ +          G  +    S C Q        T        
Sbjct: 188 RLHAAPHVKHLICGHIHRTIHASASSPAGGGLPVTILKSPCHQVPMILGQGTFADSVDEP 247

Query: 241 PGWRTLELHADGTLTTE 257
             +  L    D  +   
Sbjct: 248 GAYGILLALKDTVVVHT 264


>UniRef50_Q9V2G8 Predicted phosphohydrolase, putative n=3 Tax=Pyrococcus
           RepID=Q9V2G8_PYRAB
          Length = 505

 Score =  178 bits (452), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 54/255 (21%), Positives = 106/255 (41%), Gaps = 19/255 (7%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
           ++ I  I+DTH+  +          ++SY   L A   +   FDL++ TGD+  +     
Sbjct: 3   KMLIAHISDTHITNE--------VAFKSYAYDLIANEINTRPFDLVIHTGDVTNNGLREE 54

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFG 133
           Y+H +  +     P +  PGNHD +   Y    +  I P   V+  +   I+ LDS +  
Sbjct: 55  YEHASYLLKKIEKPLIVAPGNHDARNVGYELF-EKYIGPLIGVYEFKDGVIIWLDSTIPD 113

Query: 134 VPHGELSEFQLEWLERKLAD-APERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
           +  G +  ++ +WL+ KL + + ++  ++  HHH +P   +  +++ L NAG++  +L  
Sbjct: 114 LSDGRVGGYKFKWLKAKLEEYSHKKIKIVAAHHHLVPLPDTGRERNVLFNAGDVLDLLLS 173

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADG 252
              V   +CGH H           +        +        T       +  +++  D 
Sbjct: 174 HD-VTLYMCGHKHVPNVYRVEDLVVDNAGCASCR-------KTRKGDVNSYNIVKITKD- 224

Query: 253 TLTTEVHRLADTRFQ 267
            +   + RL     +
Sbjct: 225 KVKVVIRRLTGDEEE 239



 Score =  104 bits (259), Expect = 4e-21,   Method: Composition-based stats.
 Identities = 34/241 (14%), Positives = 89/241 (36%), Gaps = 18/241 (7%)

Query: 11  GEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQS 70
           G   +RI+ ++      + + +        + +  + AI   +++ D++V  GD+ +   
Sbjct: 254 GRRLLRIVHVS------ESNVSDRVYFRKRTLENAIRAIN-EKYKPDIVVHCGDVVEKGI 306

Query: 71  SAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQ 130
              ++   E     +A  + +PG++D     Y   ++    P   +     +  + + S 
Sbjct: 307 ERYFEMALEYYEKVKAEKIIVPGHNDISYLGYELFKEYFGEPE--IVERGDFVFIPILSA 364

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
            +    G +     + L R L D  E+  ++++HH+ +P      +   L +AG +  ++
Sbjct: 365 QYETQIGVVGRTGQKMLSRLLDDFEEKFRIIVMHHNLVPVP-GVREIGYLEDAGNVLKII 423

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHA 250
                 +  L GH      +      ++   S              +     +  ++++ 
Sbjct: 424 TD-KKTELTLTGHGGNSNAVKVEKSPIINAGSISW-------ELHRNPFGNSFNVIDIYE 475

Query: 251 D 251
           D
Sbjct: 476 D 476


>UniRef50_A3JT02 Putative uncharacterized protein n=1 Tax=Rhodobacterales bacterium
           HTCC2150 RepID=A3JT02_9RHOB
          Length = 271

 Score =  178 bits (451), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 47/255 (18%), Positives = 94/255 (36%), Gaps = 16/255 (6%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
            +IL ++D HL     + ++G+N  E  ++ L+       + D ++  GDL        +
Sbjct: 2   HKILLLSDLHLRGPNQK-IIGINPMERLKSALDHALACHPDADRLILLGDLTHSGKVLEF 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSAL---QDAGISPAKRVFIGEQWQILLLDSQ- 130
           +           P  +  GNHD +    +     +       + V     +++++LD+  
Sbjct: 61  ERLKSLTDQCPIPVTFTLGNHDNRDHFRNVFANVEPDENGHIQSVIDIGDYRMVVLDTLD 120

Query: 131 ----VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGEL 186
                     G+    +  WL++++A A  R  L+ +HH P+  G   +D   L +    
Sbjct: 121 GPPFRNYHHSGKYCAARQSWLDQQIATAEGRKILIFMHHPPMDVGFPGMDAIKLADGNAF 180

Query: 187 DTVLAKFPH-VKYLLCGHIHQELDLDWNGRRLLATPSTCVQFK---PHCSNFTLDTIAPG 242
              L ++ H   +L CGHIH+ +    NG       S   Q         +         
Sbjct: 181 ---LKRYAHKATHLFCGHIHRTISGTTNGLGFTIFKSPVHQMPMELSGTESSYSVPEPGA 237

Query: 243 WRTLELHADGTLTTE 257
           +  + L  +  +   
Sbjct: 238 YGVILLTENSIIAHT 252


>UniRef50_D2AYX4 Metallophosphoesterase n=10 Tax=Actinomycetales RepID=D2AYX4_STRRD
          Length = 247

 Score =  177 bits (450), Expect = 3e-43,   Method: Composition-based stats.
 Identities = 68/250 (27%), Positives = 101/250 (40%), Gaps = 13/250 (5%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           + QI+D HL   +               V++ +R   H  D ++ TGD+A   + A Y+ 
Sbjct: 5   LAQISDLHLDGSERAT-------RRATRVMDYLRALPHAVDALLVTGDIADHGTEAEYEE 57

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAG--ISPAKRVFIGEQWQILLLDSQVFGV 134
            A  +++   P +  PGNHD +PA   AL        P  RV       IL+ DS + G 
Sbjct: 58  AARILSA-PFPVLTCPGNHDARPAYRKALLGEPAADGPINRVHHVTGTAILMCDSTIPGR 116

Query: 135 PHGELSEFQLEWLERKLADAPER-HTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKF 193
             G L    L+W++  LA  PE    L+  H  P+       D   LR   +L  +L   
Sbjct: 117 DEGRLDAETLDWIDTTLAGLPEGTPALIAFHQPPVELHHPLPDSGMLRRPEDLAALLDAH 176

Query: 194 PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFK-PHCSNFTLD-TIAPGWRTLELHAD 251
           P V  ++ GH H      + GR L+  P+     + P   +   D    PG     L  D
Sbjct: 177 PRVAAVVTGHAHTAAASTFAGRPLIVGPAITWTLRLPWEGDRPADRDQPPGLAFHVLTED 236

Query: 252 GTLTTEVHRL 261
             LTT    +
Sbjct: 237 LRLTTHYRVV 246


>UniRef50_D2QL03 Metallophosphoesterase n=1 Tax=Spirosoma linguale DSM 74
           RepID=D2QL03_9SPHI
          Length = 247

 Score =  177 bits (449), Expect = 4e-43,   Method: Composition-based stats.
 Identities = 64/255 (25%), Positives = 103/255 (40%), Gaps = 14/255 (5%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQD-QSSAA 73
           +RI  +TD HL A+      GV+  +++   L  +   +     +V  GD       S+ 
Sbjct: 1   MRIAFLTDMHLGAEGELP-EGVDVRQNFLKALAFLTELKPSC--LVLGGDFCISVGDSSI 57

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSAL---QDAGISPAKRVFIGEQWQILLLDSQ 130
           YQ   + +     P   +PGNHD    +        D            E    L LDS 
Sbjct: 58  YQWVKKQVDELPFPYYVIPGNHDDPTMLAEVFNKMHDLHGGELYYALSLEGRPTLFLDSS 117

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQ-HSLRNAGELDTV 189
                 G  S+ Q  W    L+   + + ++ +HH PLPA   ++D+ +  R + E   +
Sbjct: 118 K-----GAFSDQQWTWFRDYLSALRDNNIVVFMHHPPLPADVQFMDRKYPFRQSEEFIEL 172

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELH 249
           +   P    ++CGH H E  +      +L +PST  Q K     F +DT+  G R + L 
Sbjct: 173 VRDLPCHVTVICGHYHVEKVVQRGNLLVLLSPSTFYQMKQDTVGFAVDTLRVGIREINLT 232

Query: 250 ADGTLTTEVHRLADT 264
             GT  + V+ L   
Sbjct: 233 THGT-NSAVYYLDPE 246


>UniRef50_Q20ZN1 Metallophosphoesterase n=1 Tax=Rhodopseudomonas palustris BisB18
           RepID=Q20ZN1_RHOPB
          Length = 252

 Score =  176 bits (448), Expect = 5e-43,   Method: Composition-based stats.
 Identities = 65/253 (25%), Positives = 102/253 (40%), Gaps = 11/253 (4%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++I+ I D HL  +  E + G +T ++++     I P     DL+V  GD+A + S   Y
Sbjct: 1   MKIIVINDLHLVPEG-ELVRGQDTNKAFECGWREIAPLVECADLVVVNGDVAHNASVEGY 59

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQ--ILLLDSQVF 132
           + F       ++  +   GNHD +  +   L  A +     V         ++LLD+ V 
Sbjct: 60  RRFRRATQEIKSKLMVTVGNHDDRERLAIELGAAHLDNTGYVQAAHHAAASVVLLDTLVP 119

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNA-GELDTVLA 191
           G P G L   +L WL  +L  A ER  + ++HH PL  G   LD+ +L +    L  +L+
Sbjct: 120 GRPEGALCAVRLAWLREQLDLAAERPVIAIMHHPPLNLGVDALDEVALLDGCDALLELLS 179

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQ-----FKPHCSNFTLDTIAPGWRTL 246
           +      LL GH H               P+            H  NF     A G   L
Sbjct: 180 RRSAPVTLLAGHHHISASGRIGPISYCICPAFSGPPARFGLWGHAPNF--GPGANGACAL 237

Query: 247 ELHADGTLTTEVH 259
            +  DG +     
Sbjct: 238 TVRQDGRVDVRTV 250


>UniRef50_A3K5W8 Phosphodiesterase n=1 Tax=Sagittula stellata E-37
           RepID=A3K5W8_9RHOB
          Length = 249

 Score =  176 bits (447), Expect = 6e-43,   Method: Composition-based stats.
 Identities = 51/236 (21%), Positives = 92/236 (38%), Gaps = 11/236 (4%)

Query: 32  ALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWL 91
            + G++ ++     L  I  H  +   +V +GDL +     AY    + +     P   +
Sbjct: 2   TIGGLDPYDRLARALGHIAEHHRDAGFVVISGDLTEYAEREAYARLRQALTMLPMPVRLM 61

Query: 92  PGNHDFQPAMYSALQDAGISPAKRV---FIGEQWQILLLDSQVFGVPHGELSEFQLEWLE 148
            GNHD +   +   +D        V       + + +  D+   G   G     +L WL 
Sbjct: 62  MGNHDDRDVFFDVFRDHPRDADGYVNHATDLREGRFIFCDTVETGRDEGHFGPGRLRWLT 121

Query: 149 RKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGE--LDTVLAKFPH-VKYLLCGHIH 205
            +LA        L  HH+PL  G    D +SLR+  +  L  +L      V Y+  GH+H
Sbjct: 122 EQLAGCE--RAFLFFHHNPLHIGDPSADGYSLRDEDQGPLRDLLKANAQKVAYMFFGHVH 179

Query: 206 QELDLDWNGRRLLATPSTCVQFKPH---CSNFTLDTIAPGWRTLELHADGTLTTEV 258
             L    +G      PST +Q  P+     +  +  + P +R + +  +  +  ++
Sbjct: 180 APLCGTMSGIAFSGVPSTMMQRIPNLTPAEHTAIGPLEPAYRVVLVRGEDVVIHQI 235


>UniRef50_B4RZD1 3,5-cyclic-nucleotide phosphodiesterase n=2 Tax=Alteromonas
           macleodii RepID=B4RZD1_ALTMD
          Length = 267

 Score =  176 bits (447), Expect = 7e-43,   Method: Composition-based stats.
 Identities = 70/269 (26%), Positives = 127/269 (47%), Gaps = 23/269 (8%)

Query: 15  VRILQITDTHLFAQKHEA-LLGVNTWESYQAVLEAIRPHQHEFD----------LIVATG 63
           ++++Q++D HL   K+E    G+  ++S +  L     H  +F+           ++ TG
Sbjct: 2   IKLIQLSDCHLLKDKNETGYAGIAPYDSLERTLLHAVNHAEQFEANNSSMAPSCFMLITG 61

Query: 64  DLAQDQSSAAYQHFAEGIASF----RAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIG 119
           D++ D +  +YQHF   +  +          L GNHD      + L D  ++        
Sbjct: 62  DISGDNTPESYQHFIALMDKYVDRANIAWFVLAGNHDNNAHFETYLGDKQLNSDNP-LTF 120

Query: 120 EQWQILLLDSQVFGVPH---GELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLD 176
           + W I  +D++     +   GE+   ++  L + +A  P+ + L+ LHHH LP+   W+D
Sbjct: 121 QNWHIHGMDTRALDSTYTAAGEVKGGEIHDLTQAVAQLPDNNHLIALHHHILPSNS-WMD 179

Query: 177 QHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDW--NGRRLLATPSTCVQFKPHCSNF 234
           +H L NA  L ++  ++  +K L+ GH+H  L      N       PSTC Q++   + F
Sbjct: 180 KHFLANAEALVSLTEQYAQIKALIHGHVHSPLRQLIGENSTPSYGCPSTCWQWEMQLA-F 238

Query: 235 TLDTIAPGWRTLELHADGTLTTEVHRLAD 263
            +   APG++ +ELH DG +   + R+  
Sbjct: 239 GVSNDAPGYQVIELHEDGVVDVSIERVEH 267


>UniRef50_Q1AXD2 Metallophosphoesterase n=1 Tax=Rubrobacter xylanophilus DSM 9941
           RepID=Q1AXD2_RUBXD
          Length = 271

 Score =  176 bits (446), Expect = 8e-43,   Method: Composition-based stats.
 Identities = 50/246 (20%), Positives = 103/246 (41%), Gaps = 21/246 (8%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +RI+Q++D H+ +       G+   E  +A +      + +  L+   GDL  +     +
Sbjct: 1   MRIVQMSDIHVGS-------GLFRPELLEAAVRETNELRPD--LVAVAGDLTMEGYRWEF 51

Query: 75  QHFAEGIASFRAP-CVWLPGNHDFQPAMYSALQDAGISPAKRVFI---GEQWQILLLDSQ 130
           +     +     P  V + GNHD +   Y   +D   S A+ + +     + +++ +DS 
Sbjct: 52  EEARRHLDRLECPHVVVVMGNHDAKSVGYRHFEDIFGSRARSLVVPSPQGEAKVVAIDST 111

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
              +  GE+      W++ +         +L++HHH L    +  D + LR+AG++  +L
Sbjct: 112 KPDLDEGEVGREYYAWIDSEFRGWERGPKILMIHHHILAVPGTGRDVNILRDAGDVMAML 171

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHA 250
            +   V  +L GH H       +G R++ + +         S     T+ P +  ++L  
Sbjct: 172 RELK-VDMVLSGHRHVPYVWSISGVRVIHSGTVS-------SLRVRGTMPPSYNLIDLDD 223

Query: 251 DGTLTT 256
           +    T
Sbjct: 224 ETVRIT 229


>UniRef50_C8S8V3 Metallophosphoesterase n=1 Tax=Ferroglobus placidus DSM 10642
           RepID=C8S8V3_FERPL
          Length = 373

 Score =  175 bits (445), Expect = 1e-42,   Method: Composition-based stats.
 Identities = 46/255 (18%), Positives = 99/255 (38%), Gaps = 24/255 (9%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++I+ I+D H   +              +  ++ I   + +  L+V TGDL+     +  
Sbjct: 1   MKIVHISDLHFGEE--------LVRSKVEKAIKQINEIEPD--LVVVTGDLSCWGIHSEL 50

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
           +   E +   ++    +PGNHD +        +      K+++   +  I+ +DS    +
Sbjct: 51  REAYEALEKLKSDYFVVPGNHDARNNGIEFF-ELYFGERKKIYKDSEVVIIGVDSTQPDI 109

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
             G +   Q  W+E       +R  +L LHHH +P   +  +++ L +AGE+  +L    
Sbjct: 110 DDGYIGFEQRRWIEENFR--KDRINVLALHHHIVPIPDTGRERNVLIDAGEVVEMLINL- 166

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA-PGWRTLELHADGT 253
               +L GH H    +      ++   S          +F +  +    +  +EL  D  
Sbjct: 167 GFALVLAGHRHMPYSIRLMRTHIIHAGS--------LGSFKILGMPDHNYNVIELSED-Y 217

Query: 254 LTTEVHRLADTRFQP 268
           ++ ++  +       
Sbjct: 218 VSLKLKFVDYGEIDV 232


>UniRef50_D0L6V7 Metallophosphoesterase n=1 Tax=Gordonia bronchialis DSM 43247
           RepID=D0L6V7_GORB4
          Length = 245

 Score =  175 bits (444), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 51/248 (20%), Positives = 89/248 (35%), Gaps = 11/248 (4%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           +  I+D H    +             ++ L  I       D ++ TGDLA + S++ Y+ 
Sbjct: 4   VAHISDLHFNGTRFN-------RSRIESTLSYINARADGIDALLITGDLADEGSASEYRE 56

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGI-SPAKRVFIGEQWQILLLDSQVFGVP 135
               + S   P +   GNHD +    +AL D     P            L+ DS + G  
Sbjct: 57  AYGVLES-PLPMLITAGNHDVRENFSAALLDHETSEPLNWSQRIGDVLFLVADSSIAGRN 115

Query: 136 HGELSEFQLEWLERKLADAPER-HTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
            G LS+  L W+  ++    +    L+  HH P+     ++D         L  ++ + P
Sbjct: 116 DGYLSDDTLTWMADEITMHGDETPVLIAFHHPPVKLSMPFMDSIRQTGEDRLAALVGRHP 175

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFK-PHCSNFTLDTIAPGWRTLELHADGT 253
           ++   LCGH H      +  R L   P        P   +  ++   P      +  +G 
Sbjct: 176 NIVAFLCGHAHTPAVTRFADRPLCIAPGVASTLNLPFEGHDIVNRGQPPGIAFHILDEGR 235

Query: 254 LTTEVHRL 261
             T    +
Sbjct: 236 FVTHFRSV 243


>UniRef50_Q15YS5 Metallophosphoesterase n=1 Tax=Pseudoalteromonas atlantica T6c
           RepID=Q15YS5_PSEA6
          Length = 250

 Score =  174 bits (442), Expect = 3e-42,   Method: Composition-based stats.
 Identities = 73/255 (28%), Positives = 130/255 (50%), Gaps = 13/255 (5%)

Query: 14  RVRILQITDTHLFAQ-KHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS- 71
             ++ QI+D HLFA  +H     +N + + QAVL+ +     +   ++ +GD++ +  + 
Sbjct: 2   SFKVAQISDCHLFADKRHAGYQNINPYTTLQAVLKNVGLCHPDM--VIVSGDVSAENDAV 59

Query: 72  ---AAYQHFAEGIASFRA--PCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILL 126
              A+YQ F++     +   P + +PGNHD   A+ + L      P      G  W++  
Sbjct: 60  KGLASYQLFSQLWQQSKISAPLLVIPGNHDHLEALNNELNHLAGWPLSTS-AGPYWKVHG 118

Query: 127 LDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGEL 186
           L++       GE+S  QL++L  ++   P++H LL++HHHP   G  W+D H  RN  E 
Sbjct: 119 LNT-KTDDSSGEISMRQLQYLNEQVNLHPQQHHLLVVHHHPYACG-GWMDNHPWRNRDEF 176

Query: 187 DTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTL 246
              + + P +K ++ GHIHQ  +        ++ PSTC Q+  +   F+    APG+R +
Sbjct: 177 IQNVEQQPQIKAVIYGHIHQASETRSQDCVFMSAPSTCWQWA-NSKEFSASGEAPGYRVI 235

Query: 247 ELHADGTLTTEVHRL 261
           EL  +G + + + R+
Sbjct: 236 ELADNGQVDSHIIRI 250


>UniRef50_D2PMS5 Metallophosphoesterase n=1 Tax=Kribbella flavida DSM 17836
           RepID=D2PMS5_9ACTO
          Length = 249

 Score =  174 bits (441), Expect = 3e-42,   Method: Composition-based stats.
 Identities = 69/251 (27%), Positives = 105/251 (41%), Gaps = 20/251 (7%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           I  ++D HL              +  + V   +R      D+++ TGDLA   +   Y  
Sbjct: 4   IAHLSDPHLDGTPE-------AQDRLRRVTAYVRSFTRPVDVVLVTGDLADHGT--EYAE 54

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQDA-----GISPAKRVFIGEQWQILLLDSQV 131
            A  +A+F  P + LPGNHD      + L           P  +V      + +LLD+ V
Sbjct: 55  VAAELAAFDVPVLVLPGNHDLSEPFRAGLTAYVDSPGAGHPVHQVRDVGGARFVLLDTTV 114

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
            G  HGEL+   L WL+  L++  +    +  HH P+      +DQ  LR+A     VL 
Sbjct: 115 PGEDHGELAAESLGWLDGVLSEPTDGPVFVAFHHPPVGLHAPAIDQWLLRDAAPFAAVLR 174

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATP----STCVQFKPHCSNFTLDTIAPGWRTLE 247
           + P V  L  GH+H  +   +    LL  P    +  + F+P  +   LD  AP    L 
Sbjct: 175 RHP-VTALFAGHLHNGVATTFADLPLLLAPGIRSAVPLPFEPAAAQGLLDPTAPPGLALH 233

Query: 248 LH-ADGTLTTE 257
           LH  D  + T+
Sbjct: 234 LHTPDAAVVTK 244


>UniRef50_A1AWV4 Metallophosphoesterase n=5 Tax=Bacteria RepID=A1AWV4_RUTMC
          Length = 234

 Score =  173 bits (440), Expect = 4e-42,   Method: Composition-based stats.
 Identities = 59/248 (23%), Positives = 110/248 (44%), Gaps = 16/248 (6%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
               +QI+D H+     E  +GVNT           +    + D ++ +GDL  + +  +
Sbjct: 3   SHSFVQISDCHI--DNVEYAMGVNTH--VNLKKIINKIINIDTDALLISGDLTHNGTITS 58

Query: 74  YQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFG 133
           Y+   + +   +   + + GNHD    + +       S     F   +W+I+  +S    
Sbjct: 59  YKTLQQILFPVQIKLLVISGNHDIDNNLNTIFSKNLFSQ----FTLRKWEIISTNSVQTS 114

Query: 134 VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKF 193
              G L++ +L+ L   L  +  ++ L++LHH  +P   +W D  SL N   L  VL K+
Sbjct: 115 KTSGFLTKNELKKLNFNLTQSIAKYILIVLHHPIVPMNSTWDDSLSLENPKALFNVLDKY 174

Query: 194 PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGT 253
           P ++ +L GH HQ  +    G ++++ PST +QF         +    G+    L+ +G 
Sbjct: 175 PKIQAILFGHAHQAAEFSRLGVKIISCPSTALQFN--------NETRIGFNHYTLYDNGQ 226

Query: 254 LTTEVHRL 261
           LT +   +
Sbjct: 227 LTIDTQWI 234


>UniRef50_D2QP98 Metallophosphoesterase n=1 Tax=Spirosoma linguale DSM 74
           RepID=D2QP98_9SPHI
          Length = 304

 Score =  173 bits (439), Expect = 5e-42,   Method: Composition-based stats.
 Identities = 52/290 (17%), Positives = 101/290 (34%), Gaps = 47/290 (16%)

Query: 2   ESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVA 61
           E+ +   LA +  VR   + DTH+              E        ++    +   I+ 
Sbjct: 19  EAAIAPNLARKRSVRFAYLGDTHITPDAK-------PVERIAKCFHHVQNQADKPSFILH 71

Query: 62  TGDLAQDQSSAAYQHFAEGIASFR--------APCVWLPGNHDFQPAMYSALQDAGISP- 112
            GD+  D  +   Q   +   ++          P  +  GNHD      +A  D      
Sbjct: 72  GGDVIMDALAEDRQKVQQQWDAWNGLVKADNSLPIEYCIGNHDI-WGFENAKNDLLYGKK 130

Query: 113 ----------AKRVFIGEQWQILLLDSQVFGVPH----GELSEFQLEWLERKLADAPERH 158
                       R F    W  ++LDS           G +   Q++WL+  LA    + 
Sbjct: 131 WAIDQMKISGRYRSFDRNGWHFIVLDSVQPKPDGKWYTGNIDAEQMDWLKADLAKTNPKT 190

Query: 159 TLLLLHHHPLPAGCSWLDQHSLRNAG-------------ELDTVLAKFPHVKYLLCGHIH 205
            +L+L H P+ +   +    ++++               +L  +  ++P+VK  L GH+H
Sbjct: 191 PILVLSHIPIFSPTGFFSDTNVKDGNWTISAGTILANTPDLLKLFYQYPNVKAALSGHMH 250

Query: 206 QELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLT 255
               +++NG   L   +    +     +        G+   +L+ DG++ 
Sbjct: 251 LLDRVEYNGVAYLCNGAVSGNWWK---SDVYQQTKAGYALFDLYDDGSVE 297


>UniRef50_A9CI50 Putative uncharacterized protein n=1 Tax=Agrobacterium tumefaciens
           str. C58 RepID=A9CI50_AGRT5
          Length = 291

 Score =  173 bits (439), Expect = 5e-42,   Method: Composition-based stats.
 Identities = 59/255 (23%), Positives = 99/255 (38%), Gaps = 11/255 (4%)

Query: 12  EARVRILQITDTHLF-AQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQS 70
             RV  + +TD H+   Q  +  L   T  +  A L  ++      + IV +GDL     
Sbjct: 2   SDRVNFVHLTDLHIGNPQVQDDDLYSETSATLSATLAQVKALVPPPEFIVVSGDLTNRGD 61

Query: 71  SAAYQHFAEGIAS--FRAPCVWLPGNHDFQPAMYSALQDAGIS---PAKRVFIGEQWQIL 125
           + +Y+     +A     AP ++  GNHD +   Y  + D       P     +     I+
Sbjct: 62  AGSYEELKRLMAEAELDAPVLFALGNHDRRDGFYPVMLDRHEGVDEPYDHAEVIAGIHII 121

Query: 126 LLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHP---LPAGCSWLDQHSLRN 182
           ++D+ V G   G     Q+EWLE +L + PE   LL++HH P        +  +  S  +
Sbjct: 122 VMDTSVPGKVGGAFEPGQIEWLEEELENHPELPKLLVMHHAPALDFDRPEAEWESLSFDD 181

Query: 183 AGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDT-IAP 241
              LD +L +   V  +L GHIH +    W G  ++          P   +  +      
Sbjct: 182 TEALDELLFEHD-VIGILAGHIHCDRMSHWQGIPVVVGIGQHFATDPLWLHEGVRMLSGA 240

Query: 242 GWRTLELHADGTLTT 256
            +    +   G   T
Sbjct: 241 SFAIGTIRDTGLTVT 255


>UniRef50_C7D3F7 Predicted protein n=5 Tax=Enterococcus RepID=C7D3F7_ENTFA
          Length = 272

 Score =  173 bits (439), Expect = 6e-42,   Method: Composition-based stats.
 Identities = 50/254 (19%), Positives = 91/254 (35%), Gaps = 18/254 (7%)

Query: 15  VRILQITDTHLFAQKHEALLGV--------NTWESYQAVLEAIRPHQHEFDLIVATGDLA 66
           + IL ++D H      +   G         N     ++ L ++   + + DL++ +GDL 
Sbjct: 1   MDILHLSDIHFRRNYEKTKDGYKGMLTKMENPLIRLESSLTSLLKIK-KIDLVIISGDLT 59

Query: 67  QDQSSAAYQHFAEGIASF--RAPCVWLPGNHDFQPAMYSALQDAGISPAKR--VFIGEQW 122
           +D     Y    + + +     P +   GNHD +        +   +      V    ++
Sbjct: 60  EDGEPEDYAFLKQKLQTILQGIPMIVTLGNHDIKKNFRIGWLNQIGTERPYNVVQTYPEF 119

Query: 123 QILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRN 182
            I+ LD+     P G +++ Q +WL+  L    ++  LL++HHH L    S     +L  
Sbjct: 120 HIISLDNSEHDNPDGHMNKEQKDWLQTTLKKLSDKPILLVMHHHLLREQSSMP---TLPE 176

Query: 183 AGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPG 242
           A E   +L K   +  +L GH H       NG             +             G
Sbjct: 177 AEETIQLL-KSSDILGVLTGHTHHPYLHHINGIPYYTVAGMSFVGEDEGQGIVRFEENYG 235

Query: 243 WRTLELHADGTLTT 256
           +    +   G  T 
Sbjct: 236 YNLYSIDK-GRFTH 248


>UniRef50_C7PKP5 Metallophosphoesterase n=1 Tax=Chitinophaga pinensis DSM 2588
           RepID=C7PKP5_CHIPD
          Length = 303

 Score =  173 bits (438), Expect = 8e-42,   Method: Composition-based stats.
 Identities = 56/292 (19%), Positives = 107/292 (36%), Gaps = 45/292 (15%)

Query: 1   MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV 60
           + S        +  +R+  ITD HL+ +           + ++  L  I+  Q + D+I+
Sbjct: 21  LPS-FAADAEKKPVLRVAHITDVHLYDKAGAP-------DFFRKCLHHIQSQQPKVDMIL 72

Query: 61  ATGDLAQDQSSA-------AYQHFAEGIAS-FRAPCVWLPGNHDF----QPAMYSALQDA 108
             GD+  D +          ++     +      P  +  GNHD          +     
Sbjct: 73  NGGDIVFDMNKENLSTIDVQWKLLHTIMKEECSLPVHYALGNHDIWWSENNKGQAVYGKQ 132

Query: 109 G------ISPAKRVFIGEQWQILLLDSQVFGVPH----GELSEFQLEWLERKLADAPERH 158
                  ++     F    W+ ++LDS    V      G+L E Q+ WL  +L     + 
Sbjct: 133 YSLDQLQLNSPYYSFTKGGWKFIVLDSVHLDVDDTWYIGKLGEAQMIWLSDELKATDAQT 192

Query: 159 TLLLLHHHPLPAGCSWLDQHSL-----------RNAGELDTVLAKFPHVKYLLCGHIHQE 207
            + +L H P+      +  + +            +  ++  +  ++P+VK  L GHIH +
Sbjct: 193 PVCVLSHIPILTATLMVQDNIVNRWEMLGGDMHTDTADIIRLFYQYPNVKLCLSGHIHLK 252

Query: 208 LDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTEVH 259
             + +N    L   +    +    +       APG+  LEL ADG+ T +  
Sbjct: 253 DKVVYNNVAYLCDGAVSGAWWKGNNR----ETAPGYGLLELFADGSFTEKYV 300


>UniRef50_O66909 Putative uncharacterized protein n=1 Tax=Aquifex aeolicus
           RepID=O66909_AQUAE
          Length = 249

 Score =  171 bits (435), Expect = 2e-41,   Method: Composition-based stats.
 Identities = 54/265 (20%), Positives = 105/265 (39%), Gaps = 25/265 (9%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           ++I  I+D H+  + +E  LG N       +++ +   + +  L++ TGDL      A Y
Sbjct: 1   MKIAHISDLHVKCEWYEDRLGNN-------LVKYLNAQKPD--LLIITGDLTDYGYYAEY 51

Query: 75  QHFAEGIASFRA-PCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFG 133
           +     +        V +PGNHD +   Y   ++   +     +  E   I+ +DS +  
Sbjct: 52  KRAYSFLELIEVEKRVVVPGNHDARNEGYELFEEFFGTRMPY-YEDEYMVIIGMDSSLPD 110

Query: 134 VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKF 193
              G +     ++L   L D  ++  ++ LHHH +P   +  D   L +AG L  V+ + 
Sbjct: 111 REEGHIGRKGYKFLRETLKDKGDKLKIVALHHHVVPIPATGSDLAILTDAGNLMKVVDEL 170

Query: 194 PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADG- 252
             V+ +L GH H+      N      T  T    +    ++      P +  L L  +  
Sbjct: 171 -GVELVLTGHKHKAWVWKLNE-TYYVTAGTATTRRLKAKDY------PSFYMLYLEDEKN 222

Query: 253 ----TLTTEVHRLADTRFQPDTASE 273
                + TE  ++ +  +  +    
Sbjct: 223 IRMEKVNTETLKVEEV-YTLNFEEG 246


>UniRef50_Q1AVF9 Metallophosphoesterase n=1 Tax=Rubrobacter xylanophilus DSM 9941
           RepID=Q1AVF9_RUBXD
          Length = 274

 Score =  171 bits (435), Expect = 2e-41,   Method: Composition-based stats.
 Identities = 51/269 (18%), Positives = 100/269 (37%), Gaps = 25/269 (9%)

Query: 9   LAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQD 68
           ++ + R+ I QI+D H  +            +  +  +  I     +   +V +GDL   
Sbjct: 1   MSTQGRLTICQISDIHCGSP-------YFIPDLLERSILEINDL--DPTAVVVSGDLTNA 51

Query: 69  QSSAAYQHFAEGIASFRAP-CVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLL 127
                Y+  AE I  FR    + +PGNHD +   Y   +         V   E   ++ +
Sbjct: 52  GYRQEYEQAAEYIRRFRCEHLMVIPGNHDSRNVGYVHFERL-FGERYSVIDFEDAIMVGV 110

Query: 128 DSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELD 187
           DS    +  G +      ++    A A E+  + ++HHH +P   +  +++ + +AG++ 
Sbjct: 111 DSSEPDLNDGRVGREHYGFIHESFAGAEEKLKIFVVHHHLIPIPGTGRERNIVFDAGDVL 170

Query: 188 TVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLE 247
            +LA    V  +L GH H           ++   +         +        P +  +E
Sbjct: 171 ELLAD-TEVDLVLSGHKHVPYSWRLENMFIVNAGTAS-------TTRLRGNTRPCYNIIE 222

Query: 248 LHADGTLTTEVHRLADTRFQ---PDTASE 273
           +  +      V R    R +    D  +E
Sbjct: 223 VENE---RVRVFRKYPFRERELVVDFNAE 248


>UniRef50_Q7NJG1 Glr1871 protein n=1 Tax=Gloeobacter violaceus RepID=Q7NJG1_GLOVI
          Length = 318

 Score =  170 bits (432), Expect = 3e-41,   Method: Composition-based stats.
 Identities = 50/238 (21%), Positives = 89/238 (37%), Gaps = 14/238 (5%)

Query: 2   ESLLTLPLAGEARVRILQITDTHLFAQKHEA--LLGVNTWESYQAVLEAIRPHQHEFDLI 59
             +   P+  E ++  +QI+D HL      +   L        Q  +E +       D +
Sbjct: 12  PPMEKPPVKLEPQLNFVQISDVHLRPNAGRSGWWLSERPEHLLQLAVEKVCALG-GVDFV 70

Query: 60  VATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMY------SALQDAGISP- 112
           V TGDL     +AA   F     +   P   + GNHD     +          +    P 
Sbjct: 71  VFTGDLFDQAEAAALDQFVAIAGALPCPYHVVVGNHDVVGKPWPGRLTKQTFAERLALPE 130

Query: 113 -AKRVF-IGEQWQILLLDSQVFGVPH--GELSEFQLEWLERKLADAPERHTLLLLHHHPL 168
                  +   +++++LD+     PH  G L   Q+EWL  +L    +   ++ LHH P+
Sbjct: 131 KLYYSVPVKPGYRLIVLDTVPAPFPHAQGCLPAEQMEWLRWQLLVHRDEQVIVALHHPPV 190

Query: 169 PAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQ 226
                   + +  +  +   ++A  P+V  +L GH+H      +  R   + PS    
Sbjct: 191 APAYFRDFRLNPLDGSQFAELMAASPNVVAVLSGHLHVPRRWSYRKRPYFSAPSLGGP 248


>UniRef50_A9DXP9 Putative uncharacterized protein n=1 Tax=Oceanibulbus indolifex
           HEL-45 RepID=A9DXP9_9RHOB
          Length = 268

 Score =  170 bits (432), Expect = 4e-41,   Method: Composition-based stats.
 Identities = 52/239 (21%), Positives = 90/239 (37%), Gaps = 2/239 (0%)

Query: 16  RILQITDTHLF-AQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           R + +TD H+     ++  L  +T  + + V+E I     + D +VA+GDL       +Y
Sbjct: 3   RFVHLTDLHISHPDLNDPHLQSDTPATLRRVVEVINGMAPQPDFVVASGDLTNQGDQQSY 62

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSAL-QDAGISPAKRVFIGEQWQILLLDSQVFG 133
           +   + + +  AP V   GNHD +    +        +P           ++ LDS V G
Sbjct: 63  ELLRDILGTMHAPLVLALGNHDKRAGFNAVFAPGLADAPYFHDAPQGDLHVITLDSSVPG 122

Query: 134 VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKF 193
              G L + Q E+L   L   PE   LL++HH P     +         +      + K 
Sbjct: 123 KVAGALDDAQFEFLGAALQRHPELAKLLVIHHPPRVDPEALAWGSLDEASSARLAEMLKG 182

Query: 194 PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADG 252
             V  +L GH+H      W+G  ++ +           +         G+   +    G
Sbjct: 183 QRVAGVLSGHVHVNRVSHWHGIPVVISNGLHSTIDLTETRDLRIVEGTGFGLCDWLPSG 241


>UniRef50_A3U194 Putative uncharacterized protein n=1 Tax=Oceanicola batsensis
           HTCC2597 RepID=A3U194_9RHOB
          Length = 287

 Score =  170 bits (430), Expect = 7e-41,   Method: Composition-based stats.
 Identities = 69/261 (26%), Positives = 108/261 (41%), Gaps = 17/261 (6%)

Query: 11  GEARVRILQITDTHLFAQK-HEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
            +  +  + +TD H+ A    + +L  +T E+ +  LE I         IVA+GDL    
Sbjct: 2   AQRHLTFIHMTDLHVNASGVEDDMLFNDTRETLERTLEEIGRMDDAPAFIVASGDLTNRG 61

Query: 70  SSAAYQHFAEGIAS--FRAPCVWLPGNHDFQPAMYSALQDAGIS---PAKRVFIGEQWQI 124
              AY+  AE  A+     P ++  GNHD +    +A  +       P     + +   +
Sbjct: 62  DPEAYRTVAEIFAASGLDIPVLFALGNHDKREGFAAAFPELYTDASQPFDHDRVIDGLHL 121

Query: 125 LLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHP---LPAGCSWLDQHSLR 181
           + LDS V     G     Q++WL+ +LA  P+   LL++HH P   L A     +  S  
Sbjct: 122 ITLDSSVPNEIGGYWEAGQIDWLKDRLAAHPDLPKLLVMHHAPMIDLTASDMEWESLSAV 181

Query: 182 NAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLAT----PSTCVQFKPHCSNFTLD 237
              EL T +A    V  +L GH+H +    W+G  ++        T V   P   N    
Sbjct: 182 ATEELRTAIAGHD-VVGILSGHVHMDRVAQWHGVPVIIGTGHHAGTDVVALPGAFNML-- 238

Query: 238 TIAPGWRTLELHADGTLTTEV 258
             A G+   +L   G  TT V
Sbjct: 239 -DATGFAVCQLFPAGLTTTFV 258


>UniRef50_O30241 LacZ expression regulatory protein (Icc) n=1 Tax=Archaeoglobus
           fulgidus RepID=O30241_ARCFU
          Length = 372

 Score =  168 bits (427), Expect = 1e-40,   Method: Composition-based stats.
 Identities = 54/254 (21%), Positives = 102/254 (40%), Gaps = 22/254 (8%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +RI+ I+D H   +           E  +  +  I   + +  L+V TGDL+     +  
Sbjct: 1   MRIVHISDLHFGEE--------LIREKVEKAVRQINEIEPD--LLVITGDLSCWGIHSEM 50

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGV 134
           +   E +   +   + +PGNHD +   Y   Q       K+ +  +   ++  DS    +
Sbjct: 51  RDAYETLLDLKPDYIAVPGNHDARNIGYEFFQ-LYFGETKKYWKNDVVSLIAADSTQPDL 109

Query: 135 PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFP 194
             G + + Q +W+  K+    +R  +L LHHH  P   +  +++ L +AGE+  +L    
Sbjct: 110 DDGYIGKEQRDWIVSKIR--KDRFNILALHHHIAPIPKTGRERNVLIDAGEMVELLIA-N 166

Query: 195 HVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTL 254
            +  +L GH H    L      ++    T   FK       L      +  +E+  D TL
Sbjct: 167 GISAVLAGHRHMPYSLRLMRTHVIHAG-TLGSFK------VLGMPDHNYNVIEI-KDNTL 218

Query: 255 TTEVHRLADTRFQP 268
           T ++  +     + 
Sbjct: 219 TLKLRFVDYGEVEI 232


>UniRef50_B5YAA1 Membrane-associated protein, putative n=2 Tax=Dictyoglomus
           RepID=B5YAA1_DICT6
          Length = 252

 Score =  165 bits (419), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 53/248 (21%), Positives = 96/248 (38%), Gaps = 22/248 (8%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
                I D            G      ++  L  I   + +   I+  GD+  + +   Y
Sbjct: 24  FTFAVIGD----------RAGRPVPGVFERNLSEILKRKPD--FIIQLGDILVEGTEKEY 71

Query: 75  QHFAEGIASFRAPCVWLPGNHD-FQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFG 133
           ++  E + +   P   +PGNHD ++       Q     P    F  E  + ++L++    
Sbjct: 72  KYIGELLRNVNIPFYIVPGNHDLYKDPRGEKFQKFTGRPLYYYFDYENARFIILNNS--- 128

Query: 134 VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKF 193
              G L + QLEWL   L +  +++  + +H   +  G  +L   +     ++   L + 
Sbjct: 129 --SGILGKTQLEWLTNVLKENDKKYKFVFMHQPVISPGLFFLLHKADPVESKMLMKLFEE 186

Query: 194 PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGT 253
             V Y+  GHIH     + NG   +   S     +P+ S+  LD   P +  +E+   G 
Sbjct: 187 YKVNYVFSGHIHMYYRKEINGVVYII--SGIGGARPYVSS-DLDEGKPHFVLMEVTDKG- 242

Query: 254 LTTEVHRL 261
           +  EV RL
Sbjct: 243 IKEEVVRL 250


>UniRef50_A9A2N5 Metallophosphoesterase n=4 Tax=marine archaeal group 1
           RepID=A9A2N5_NITMS
          Length = 252

 Score =  165 bits (418), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 45/262 (17%), Positives = 96/262 (36%), Gaps = 21/262 (8%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + I+QI+D H+ +            E +  ++  +     +   IV TGDL  +     Y
Sbjct: 1   MIIVQISDLHIGS--------QFLEEKFDVLVSEVNELNPDV--IVITGDLTNEGLMKEY 50

Query: 75  QHFAEGIASFR-APCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFG 133
           +     +  F     + + GNHD++   Y   +                 ++ + +    
Sbjct: 51  EKCKSLLEKFNTKKIIAISGNHDYRNTGYLLFKKFFPFQTVNELD-NDVVLVTVGTARPD 109

Query: 134 VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKF 193
              GE+   Q  WLER +    ++  ++ +HHH +    +  DQ ++ +AG++   +   
Sbjct: 110 RNEGEVGYRQNLWLERTMKKYKDKIKIVAMHHHLIAIPDTGSDQLTVVDAGDVLRTVLDS 169

Query: 194 PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGT 253
             V  +LCGH H+    ++    ++   +         S          +  L +  D  
Sbjct: 170 E-VDVVLCGHKHRPWAWNFGTLTVVNAGTA-------TSERVRGLFENTYNILTI-KDKQ 220

Query: 254 LTTEVHRLADTRFQPDTASEGY 275
           +  ++  +   R   D   + Y
Sbjct: 221 VNVDLKIVGGKRVPIDEIVKNY 242


>UniRef50_C7MAF7 Predicted phosphohydrolase n=1 Tax=Brachybacterium faecium DSM 4810
           RepID=C7MAF7_BRAFD
          Length = 284

 Score =  164 bits (416), Expect = 3e-39,   Method: Composition-based stats.
 Identities = 59/227 (25%), Positives = 99/227 (43%), Gaps = 10/227 (4%)

Query: 15  VRILQITDTHLFAQKH-EALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
           +R+L +TDTHL+          ++T  + + +L+ +     + D +V TGD ++D ++ +
Sbjct: 1   MRLLHLTDTHLYGDPAARHYDRIDTAAALRGLLDRLGTL-RDIDAVVHTGDASEDGTAQS 59

Query: 74  YQHFAEGIAS----FRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE---QWQILL 126
           Y+   E +        AP   + GNHD        +      PA +  +       ++++
Sbjct: 60  YRLLHEILDPFAASLDAPLAVVMGNHDVSAVYGETVVPGERLPAAQDRVVPLPRDGRLIV 119

Query: 127 LDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGEL 186
           LDS V G  +G L+  QL+WL  +LA      ++L +HH PL A  + L    L     L
Sbjct: 120 LDSSVPGAGYGHLAPEQLDWLREQLAVPAAGGSVLAIHHPPLVAATALLRGLDLDGLDAL 179

Query: 187 DTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSN 233
             VLA    V  +L GH H E+  +  G  +   P       P    
Sbjct: 180 AAVLAG-SDVSIVLSGHYHHEMSGEIAGIPVHVAPGITNVVDPLGGG 225


>UniRef50_A6W423 Metallophosphoesterase n=1 Tax=Kineococcus radiotolerans SRS30216
           RepID=A6W423_KINRD
          Length = 274

 Score =  164 bits (416), Expect = 3e-39,   Method: Composition-based stats.
 Identities = 69/247 (27%), Positives = 104/247 (42%), Gaps = 13/247 (5%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           R+LQ++DTHL A        V+T  +    LEA+R      D +V +GD++ D + A+Y+
Sbjct: 3   RVLQLSDTHLMAAGALHNGLVDTTAALVHALEALRDVGP-LDAVVVSGDVSDDGTVASYE 61

Query: 76  HFAEGIASF----RAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQV 131
              + +  F     A  V+  GNHD        L      P + V      +I++LDS V
Sbjct: 62  AARDLVGGFAAERGAVAVFAMGNHDVAGPFEQVL-----GPTRSVHDVAGVRIVVLDSSV 116

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
            G  +GEL   QL W    LAD   R +++++HH PLPA     +   L+   EL   LA
Sbjct: 117 PGRGYGELPAEQLSWAREVLADPAPRGSVVVVHHSPLPAPTVLHEGLRLQRPAELLDALA 176

Query: 192 KFPHVKYLLCGHIHQELDLDW-NGRRLLATPSTCVQFK-PHCSNFTLDTIAPGWRTLELH 249
               V+ +L GH H        +G      P+   +                G   ++L 
Sbjct: 177 G-TDVRAVLSGHYHHPFAATLPSGLAAFVAPAVANRCDVLVAPGRERILRGSGALLVDLD 235

Query: 250 ADGTLTT 256
             G   T
Sbjct: 236 ERGVRAT 242


>UniRef50_Q091L6 Ser/Thr protein phosphatase family protein n=1 Tax=Stigmatella
           aurantiaca DW4/3-1 RepID=Q091L6_STIAU
          Length = 343

 Score =  164 bits (415), Expect = 3e-39,   Method: Composition-based stats.
 Identities = 53/275 (19%), Positives = 98/275 (35%), Gaps = 35/275 (12%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
             + +     I+DTHL+ QK           S    ++ +     + D ++  GDLAQ  
Sbjct: 34  PEKPKFTFAYISDTHLYEQKLNDRF----VRSILKAVDDVNALDPQPDFVLFGGDLAQLG 89

Query: 70  SSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDS 129
            +   +  A+ + S +AP   + G HD+   M    ++    P    F  +    ++L+S
Sbjct: 90  QAGELKLGAQILKSVKAPVRMMVGEHDWFLDMGELWRELFGEPT-YSFDHKGIHFVVLNS 148

Query: 130 -------------------QVFGVPHG-----ELSEFQLEWLERKLADAPERHTLLLLHH 165
                               V G+ +G     E+   Q  WL++ LA   ++  +++  H
Sbjct: 149 IQEKDFWTERGLTPMQRMQIVAGLDNGIQSRFEVGAEQRAWLQKDLAKVDKKTPVIVFSH 208

Query: 166 HPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCV 225
            PL       +     +A E+  +L  F  V  ++ GH HQ L    +        ST  
Sbjct: 209 SPLYKYYKPWN-FWTDDADEVQALLKPFEKVT-VIHGHTHQLLTNRIDNIHFHGMLSTAW 266

Query: 226 QFKPHCSNFTLDTIAP----GWRTLELHADGTLTT 256
            +          T+       +   +   DG +  
Sbjct: 267 PWPYAPEGLPSFTMPMNRADPFSAFDGCGDGRMDV 301


>UniRef50_A1SEE2 Metallophosphoesterase n=2 Tax=Actinobacteria (class)
           RepID=A1SEE2_NOCSJ
          Length = 313

 Score =  163 bits (412), Expect = 7e-39,   Method: Composition-based stats.
 Identities = 70/274 (25%), Positives = 102/274 (37%), Gaps = 18/274 (6%)

Query: 13  ARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA 72
            R  +  ++D HL A        ++T    +  L  +   +     +V TGDLA     A
Sbjct: 9   PRHVVAHLSDPHLLAGGARQYGVIDTEAGLRLALTRLSRLETPPHALVFTGDLADKAEPA 68

Query: 73  AYQHFAEGI----ASFRAPCVWLPGNHDFQPAMYSAL----QDAGISPAKRVFIGEQWQI 124
           AY    E +    A   A  VW+ GNHD +      L         +P  RV      +I
Sbjct: 69  AYSRLRELVEPAAAEMGAAVVWVMGNHDERAPYARGLFGVEGADADAPQDRVHEVAGLRI 128

Query: 125 LLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHS-LRNA 183
           + LD+ V G  HGEL++ QL WL   LA      TLL LHH P+P       +   L + 
Sbjct: 129 VALDTSVPGYHHGELADDQLAWLAEVLATPAPHGTLLALHHPPIPIPMMPAAEIIELLDQ 188

Query: 184 GELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNF--TLDTIAP 241
             L  VL     V+ +L GH H      + G  +    +TC    P       +      
Sbjct: 189 HRLADVL-GGTDVRCILGGHFHYSTYSTFAGIPVSVASATCYTSDPAPLERFVSGVNGHQ 247

Query: 242 GWRTLELHADGTLTTEVHRLADTRFQPDTASEGY 275
               + L+ D  +   V  + +          GY
Sbjct: 248 AMTMVHLYDD-RVVHTVVPVDEAP-----EVSGY 275


>UniRef50_O27755 Transcriptional regulator Icc related protein n=1
           Tax=Methanothermobacter thermautotrophicus str. Delta H
           RepID=O27755_METTH
          Length = 262

 Score =  161 bits (409), Expect = 2e-38,   Method: Composition-based stats.
 Identities = 54/239 (22%), Positives = 96/239 (40%), Gaps = 21/239 (8%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           +I QI+D H   +     L  N     +             DLI+ +GDL  +  S  Y+
Sbjct: 4   KIAQISDVHFGEKNFSDQLRKNLLHQLE---------NENPDLIIVSGDLTTEGYSHEYE 54

Query: 76  HFAEGIASFRA--PCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFG 133
             A  +   R       +PGNHD +       +   I   K V    ++ ++ LDS    
Sbjct: 55  LAAAFVDELRTITSTYTIPGNHDARNVGLIHFEKL-IGRRKFVHHDSEFAVIGLDSSEPD 113

Query: 134 VPHGELSEFQLEWLERKLADAPERH-TLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
           +  G++   QL+WL ++L   P+    ++  HHH LP   +  +++ L ++G+L  +L +
Sbjct: 114 INDGQIGMDQLDWLRKELERVPDHLCKIVTFHHHLLPIPNTGRERNILLDSGDLLKLLKE 173

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHAD 251
           +  V ++L GH H        G   L + +         +        P    L ++ D
Sbjct: 174 Y-GVDFVLNGHKHVPNVWMIEGMVTLNSGTA-------TTRKLRGETFPSHNQLRINDD 224


>UniRef50_B1LAV7 Metallophosphoesterase n=2 Tax=Thermotoga sp. RQ2
           RepID=B1LAV7_THESQ
          Length = 343

 Score =  161 bits (408), Expect = 2e-38,   Method: Composition-based stats.
 Identities = 47/238 (19%), Positives = 89/238 (37%), Gaps = 17/238 (7%)

Query: 34  LGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPG 93
              N+  ++  +++A+   Q      V TGD+  D S   ++ + E +  F+ P + +PG
Sbjct: 46  DNKNSISTFSKLIDAVNREQ-NAAFAVNTGDMVFDGSLFKWELYLEQLRRFKIPVLPVPG 104

Query: 94  NHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLAD 153
           NHD      + L      P    F       ++L++         +  +QLEWL+++L  
Sbjct: 105 NHDLADDPGNYL--KIFGPLYYSFHTGNSYFIVLNNA----NEKYVDAYQLEWLKKELEK 158

Query: 154 APERHTLLLLHHHPLPAGC----SWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELD 209
           +       +  H P+               L NA  L  +L ++ +V  +  GHIH    
Sbjct: 159 SQSYRYRFVFMHVPVYDPRKEKQPGHSMKDLENAQTLLNILKEY-NVTMVFAGHIHGYFR 217

Query: 210 LDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTEVHRLADTRFQ 267
            +WNG   + T                +     +  + +   G +  +V +L    F 
Sbjct: 218 GEWNGVSYIITGGAG----AELFGTDPEHYFYHFIRVHVSPTG-VKYDVIKLPTPGFN 270


>UniRef50_B9TNQ0 Putative uncharacterized protein (Fragment) n=1 Tax=Ricinus
           communis RepID=B9TNQ0_RICCO
          Length = 257

 Score =  160 bits (406), Expect = 4e-38,   Method: Composition-based stats.
 Identities = 42/256 (16%), Positives = 92/256 (35%), Gaps = 37/256 (14%)

Query: 37  NTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA-------AYQHFAEGIA-SFRAPC 88
           +    +   L  ++    + D+++  GD+  D +          ++     +      P 
Sbjct: 4   DAPARFTRCLHHLQQQTPKVDMVLNGGDIVFDMNKENISTINDQWKLVQNIMKNECSLPV 63

Query: 89  VWLPGNHDF----QPAMYS------ALQDAGISPAKRVFIGEQWQILLLDSQVFGVPH-- 136
            +  GNHD          +      AL    +       +   W+I++LDS    + +  
Sbjct: 64  HYCLGNHDIWWYEDDKGQAIYGKKYALDKLQLVKPYYSLVKNGWKIIVLDSVHLDIDNTW 123

Query: 137 --GELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL-----------RNA 183
             G+L + QL WL  +L        ++++ H P+      ++   +            + 
Sbjct: 124 YIGKLGDEQLNWLSDELKATDANMPVMVMSHIPILTALLMIEDDIVNKWTMLGGDMHTDT 183

Query: 184 GELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGW 243
            ++  +  + P+VK  + GH+H    + +N    L   +    +            APG+
Sbjct: 184 AKIINLFYRHPNVKLCVSGHLHMRDKVVYNNVTYLCNGAVSGAWWEG----NRRETAPGY 239

Query: 244 RTLELHADGTLTTEVH 259
             ++L+ADGT   +  
Sbjct: 240 GLIDLYADGTFEEKYV 255


>UniRef50_D0LMB8 Metallophosphoesterase n=1 Tax=Haliangium ochraceum DSM 14365
           RepID=D0LMB8_HALO1
          Length = 374

 Score =  160 bits (406), Expect = 4e-38,   Method: Composition-based stats.
 Identities = 51/275 (18%), Positives = 94/275 (34%), Gaps = 35/275 (12%)

Query: 11  GEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQS 70
           G+   R   I+D+HL+ +            +    +E I     + D +   GDLAQ   
Sbjct: 66  GDGGFRFAYISDSHLYPETKNDRF----VRALMRAVEDINRLDPQPDFVFYGGDLAQLGR 121

Query: 71  SAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDS- 129
                  A+ +   +AP   + G HD+   M    +     P    +  +   +++L+S 
Sbjct: 122 PDELGLGAQILKEVKAPLKMMVGEHDWYYDMGETWRGLFGEPR-YSWDHKGVHLVVLNSV 180

Query: 130 ------------------QVFGVPHGE-----LSEFQLEWLERKLADAPERHTLLLLHHH 166
                              V G+ +G      + + Q+ WL+  LA       +++  H 
Sbjct: 181 IEEDFWTARGLTPEQRMQTVAGLDNGAQNPFTVGDEQIAWLKNDLAQVDRNTPIIVFSHS 240

Query: 167 PLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQ 226
           PL       +     +A ++  VL  F  V  ++ GH HQ L             ST   
Sbjct: 241 PLYKLYKKWN-FWTDDAEKVQAVLQPFRKVT-VIHGHTHQILTNRIGNIHFHGMLSTAWP 298

Query: 227 F---KPHCSNFTLDTIAP-GWRTLELHADGTLTTE 257
           +         +T++   P  +   +   DG +   
Sbjct: 299 WPYAPEGMPEYTVEMSRPDPFNPNDGCGDGQVIVH 333


>UniRef50_A0QKV9 Metallophosphoesterase n=4 Tax=Mycobacterium RepID=A0QKV9_MYCA1
          Length = 306

 Score =  160 bits (405), Expect = 5e-38,   Method: Composition-based stats.
 Identities = 38/230 (16%), Positives = 79/230 (34%), Gaps = 10/230 (4%)

Query: 11  GEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQS 70
            +  +R  QI+D+HL           +   ++   ++ +    +  D ++ TGDL    +
Sbjct: 45  AQPTLRFAQISDSHLGFTGAP---NPDVAGTFGRAIDQVNNLGYTPDFVIHTGDLTHLST 101

Query: 71  SAAYQHFAEGIASFRAP-CVWLPGNHDFQP----AMYSALQDAGISPAKRVFIGEQWQIL 125
              +    + +++ + P    +PG HD          S                    ++
Sbjct: 102 PEQFDQAKQMMSALKTPHVFTVPGEHDSVDDAGQKYRSVFGAGSAGDGWYSLDVAGVHLI 161

Query: 126 LLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGE 185
            L + +     G L   QLE++++ +A       +++  H PL A           +A +
Sbjct: 162 ALVNTLNLRKLGHLGADQLEFVKKDVAGLSSDTPIIVFSHIPLFAMYPQW-GWGTDDAAQ 220

Query: 186 LDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFT 235
             + L +F  V   L GH+HQ      +     +  +T            
Sbjct: 221 ALSYLRRFASVT-CLNGHVHQLFSKTEDNVTFHSGTTTAYPLPHPGDGPA 269


>UniRef50_Q5UEX4 Predicted Ser/Thr protein phosphatase family protein n=1
           Tax=uncultured alpha proteobacterium EBAC2C11
           RepID=Q5UEX4_9PROT
          Length = 256

 Score =  159 bits (404), Expect = 6e-38,   Method: Composition-based stats.
 Identities = 46/257 (17%), Positives = 89/257 (34%), Gaps = 9/257 (3%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + + QI+DTHL         G     + +  +EAI       D+++ TGDL+ + SSA  
Sbjct: 1   MLVAQISDTHLITPGGPGRFGNEKLIALEKCIEAINNLDTLPDVVIHTGDLSDNGSSAEL 60

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQD-----AGISPAKRVFIGEQWQILLLDS 129
               + +     P    PGN D    +     +         P   +      ++  LD+
Sbjct: 61  LLAKKHLDKLVVPYYVTPGNKDCADKLIEVFTEQLSDVVTGGPITYLVDSLPIKLASLDT 120

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL--RNAGELD 187
                  G L   ++  +++ L+   +   ++  HH P          +     N+ +L 
Sbjct: 121 TTSLDNRGLLDFKKIAAIDKVLSMHQDDPVIIFSHHPPFNLSSENSPHYEFVSENSIKLF 180

Query: 188 -TVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTL 246
             ++ +   +  L CGH H+ +            P  C       +    + I   ++  
Sbjct: 181 DELVDRHAQIVALFCGHFHRPIRKSMGLFDANIAPPVCNLIDYSSTKTGPNHIGN-FQLH 239

Query: 247 ELHADGTLTTEVHRLAD 263
                   TTEV  ++ 
Sbjct: 240 NFGKGYEFTTEVKMISH 256


>UniRef50_Q64Z92 Serine/threonine protein kinase related protein n=12
           Tax=Bacteroidales RepID=Q64Z92_BACFR
          Length = 621

 Score =  159 bits (404), Expect = 7e-38,   Method: Composition-based stats.
 Identities = 43/268 (16%), Positives = 100/268 (37%), Gaps = 34/268 (12%)

Query: 4   LLTLPLAGE----ARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLI 59
              LP+A         R  Q+TD HL     +        E  +  +E I       D +
Sbjct: 13  FFLLPVATRAQVTGSFRFAQLTDIHLNPNNPK------PTEDLKRSVEQINA-TPGVDFV 65

Query: 60  VATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQ--PAMYSALQDAGISPAKRVF 117
           + TGDL ++            +   +     +PGNH+ +   +  +A  +         F
Sbjct: 66  LVTGDLTEEGDRTTMLVVKSILDQLKVKYYVIPGNHETKWSDSGCTAFSEIFGGER-FKF 124

Query: 118 IGEQWQILLLDS-QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLD 176
             + +  L  +S  +  + +G +    + W+++++    +   ++L+ H+P       + 
Sbjct: 125 EHKGFLFLGFNSGPLMRMAYGHVVPQDITWMKQEMDKVGKDKPVILVTHYP-------MQ 177

Query: 177 QHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTL 236
              + N  ++   +  + +++  + GH H+   L ++G   + T S          N   
Sbjct: 178 DGDVDNWYDVTDAVRPY-NIRTFIGGHYHRNRFLSYDGIPGILTRS----------NLRD 226

Query: 237 DTIAPGWRTLELHADGTLTTEVHRLADT 264
              + G+   ++  D ++ T   R+ + 
Sbjct: 227 KNGSSGYSIFDITPD-SIITYEQRIDEP 253


>UniRef50_A9WNR5 Putative 3',5'-cyclic-nucleotide phosphodiesterase n=1
           Tax=Renibacterium salmoninarum ATCC 33209
           RepID=A9WNR5_RENSM
          Length = 309

 Score =  159 bits (404), Expect = 7e-38,   Method: Composition-based stats.
 Identities = 67/229 (29%), Positives = 106/229 (46%), Gaps = 21/229 (9%)

Query: 13  ARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA 72
             + IL ++DTH+ A+   +   V+T ++    L A+ P   E DL+V +GD++ D ++ 
Sbjct: 8   ETLSILHLSDTHVLAKGLHS-NVVDTRQNLLEALRALVP-VEELDLVVVSGDVSDDGTAE 65

Query: 73  AYQHFAEGIASF----RAPCVWLPGNHDFQPAMYSAL----------QDAGISPAKRVFI 118
           +Y+   E + +F     A  ++  GNHD +P  +  L          QD G  P     +
Sbjct: 66  SYRMVQELVENFASHRGARAIYTMGNHDGRPGFWEVLGNGHPDSPAEQDGGQLPVYGSSV 125

Query: 119 GEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQH 178
              ++I+ LD+ V G  HG L   QL+WL  +L  A E  T+L+LHH P+       D  
Sbjct: 126 LGGFRIISLDTSVPGRTHGYLDRGQLDWLTEELGSASEAGTVLVLHHPPVEPVTPLHDGI 185

Query: 179 SLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDW----NGRRLLATPST 223
            L+N  +L  VL     V+ +L GH H  L            +L  P  
Sbjct: 186 ELQNPEDLLEVLHG-SDVRLILSGHYHHGLVDSVLLGDQLIPVLVAPGI 233


>UniRef50_D2QD99 Metallophosphoesterase n=1 Tax=Spirosoma linguale DSM 74
           RepID=D2QD99_9SPHI
          Length = 306

 Score =  159 bits (403), Expect = 8e-38,   Method: Composition-based stats.
 Identities = 55/281 (19%), Positives = 103/281 (36%), Gaps = 46/281 (16%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
             +  +R+  +TD H+          +   + ++  L  ++    + DLI+  GD   + 
Sbjct: 31  PRQRVLRVAHLTDVHMQPI-------IGAAKGFEKCLHHVQSLPDKPDLIINGGDAVMEA 83

Query: 70  S-------SAAYQHFAEGIASFRA-PCVWLPGNHDF----------QPAMYSALQDAGIS 111
                   S  ++ + + + S  A P +   GNHD           +     A+ +  ++
Sbjct: 84  HGRGKDSVSRQWRLYQDVLRSENALPVISCVGNHDIWCKQETKICFEAGRQWAMDEFQMA 143

Query: 112 PAKRVFIGEQWQILLLDSQVFGVPH----GELSEFQLEWLERKLADAPERHTLLLLHHHP 167
                     W+I++LDS             L + Q  WLE +L   P    +L++ H P
Sbjct: 144 KRFYSIDRNGWRIIMLDSVQPKADGSWYTAHLDDEQYHWLEAELKSTPNTTPILVVSHIP 203

Query: 168 LPAGCSWLDQHSLRNAG-------------ELDTVLAKFPHVKYLLCGHIHQELDLDWNG 214
           + A C + D     +                L  +    P+VK  L GHIH    +D+NG
Sbjct: 204 ILAACVFFDGPRFSDENWSVPARWMHSDTVRLTNLFHNHPNVKAALSGHIHLTDRVDYNG 263

Query: 215 RRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLT 255
                  +    +     +      A G+  ++L+ DGT+ 
Sbjct: 264 VSYYCNGAVSGAWWFGKYH----HTAAGYALVDLYDDGTVQ 300


>UniRef50_C5EL28 Predicted protein n=1 Tax=Clostridiales bacterium 1_7_47FAA
           RepID=C5EL28_9FIRM
          Length = 288

 Score =  159 bits (403), Expect = 9e-38,   Method: Composition-based stats.
 Identities = 61/275 (22%), Positives = 95/275 (34%), Gaps = 39/275 (14%)

Query: 15  VRILQITDTHLFAQ---KHEALLGV----------------------------NTWESYQ 43
           + IL ++D H   +   + EA  G                             N      
Sbjct: 1   MYILHLSDIHYRRELGRRKEADRGRADGEDKQHESGGRLAGPDGYQAMLSAMQNPLVFLD 60

Query: 44  AVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASF--RAPCVWLPGNHDFQPAM 101
             L+         DL+V TGDL +D ++  Y+     I       P V   GNHD + + 
Sbjct: 61  DCLDRAARDWKTIDLVVITGDLTEDGTAEDYRCLKHHIRERVGDIPLVVTLGNHDNKRSF 120

Query: 102 YSA-LQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTL 160
               L++ G +P   +       ++  D+ V GVP G + + Q  WLER L       ++
Sbjct: 121 REGWLEEMGSAPYNTIRWVGGTAVIAFDTSVQGVPDGRMDDRQAAWLERALDAVGRNPSI 180

Query: 161 LLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLAT 220
           L+ HHH LP          L  +G+L +++     V  +LCGH H        GR     
Sbjct: 181 LVTHHHLLPEQGQIP---PLPESGKLLSLI-GNSGVCLILCGHTHHHHAGQAAGRPCHVA 236

Query: 221 PSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLT 255
            S                   G+    +  DG + 
Sbjct: 237 DSLSFCGDDMGGGQVRFQEKYGFNVYRM-EDGMVR 270


>UniRef50_Q7NSC8 Putative uncharacterized protein n=1 Tax=Chromobacterium violaceum
           RepID=Q7NSC8_CHRVO
          Length = 318

 Score =  159 bits (403), Expect = 9e-38,   Method: Composition-based stats.
 Identities = 46/231 (19%), Positives = 74/231 (32%), Gaps = 12/231 (5%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
            +QI+DTHL  ++       +   S +  +  I         +V TGD++       +  
Sbjct: 58  FVQISDTHLGFRREA---NPDVQGSLRRAIADINALAKRPAFVVHTGDVSHLSRPEEFDL 114

Query: 77  FAEGIASFRA-PCVWLPGNHDFQP----AMYSALQDAGISPAKRVFIGEQWQILLLDSQV 131
             + +   R      +PG HD                G   A   F       + L++ +
Sbjct: 115 ARQMLKDIRVDRVHTIPGEHDALDDGVSGYLKFFDHDGRHKAWYSFDQGGVHFVALNNVL 174

Query: 132 FGVPH--GELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
                    L + QL WL+R LA       +++L H PL             +A +   +
Sbjct: 175 NFSTSRLAALGDEQLAWLKRDLAGLSHSTPVIVLAHIPLWTVYEPW-GWGTADAAQAMAL 233

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA 240
           L  F  V  +L GHIHQ L        L    S              +   
Sbjct: 234 LRPFGSVT-VLNGHIHQVLQKVEGNVALHTARSLAYPLPTPGQAGFGEPAP 283


>UniRef50_Q0RKV8 Putative uncharacterized protein n=1 Tax=Frankia alni ACN14a
           RepID=Q0RKV8_FRAAA
          Length = 301

 Score =  159 bits (403), Expect = 9e-38,   Method: Composition-based stats.
 Identities = 72/282 (25%), Positives = 112/282 (39%), Gaps = 22/282 (7%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
            G A + ++Q++DTHL          V+T+   + V   +         I+ TGDLA D 
Sbjct: 4   TGPAELTLIQVSDTHLLPAGQLMHDRVDTFALLETVAATVASSTGPVAGILLTGDLADDG 63

Query: 70  SSAAYQHFAEGIASF----RAPCVWLPGNHDFQPAMYSALQD---------------AGI 110
           S A+Y+   + I        AP V+  GNHD + A  + L                 +  
Sbjct: 64  SPASYRRLRQIIDPLAATFDAPVVYAMGNHDERLAFRAELLGGAGVPVGLDGQAGEWSTD 123

Query: 111 SPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPA 170
            P   V + +  +++ LDS   G   G L++ QL WL   LA    R TLL++HH PLP+
Sbjct: 124 HPCDSVHLVDGLRLVALDSTTPGRHDGWLTDAQLAWLADVLATPAPRGTLLIVHHPPLPS 183

Query: 171 GCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPH 230
               +    L  A  L  V+A    V+ +L GH H        G  +  +P+      P 
Sbjct: 184 PVPTVHLLRLAAAERLADVVAG-TDVQMILSGHAHHAGAGALAGIPVWVSPALAYDTDPL 242

Query: 231 CSN-FTLDTIAPGWRTLELHADGTLTTEVHRLADTRFQPDTA 271
             +      +  G+  ++L  DG        L+      D  
Sbjct: 243 PPDGRLRGLLGGGFSRIDL-IDGQFVATAIPLSPAGQVYDND 283


>UniRef50_Q2JP63 Ser/Thr protein phosphatase family protein n=2 Tax=Synechococcus
           RepID=Q2JP63_SYNJB
          Length = 309

 Score =  159 bits (403), Expect = 1e-37,   Method: Composition-based stats.
 Identities = 62/286 (21%), Positives = 91/286 (31%), Gaps = 46/286 (16%)

Query: 14  RVRILQITDTHLFAQ-KHEALLGVN-TWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
           R+   Q++D HL  +         +      +A +  +     +   +V TGDL      
Sbjct: 5   RICFAQVSDVHLMPETGCRCWWMSDSPRRQLEAAVAHLNQ-VPDLHFVVFTGDLVDQADP 63

Query: 72  AAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSA----------------LQDAGISPAKR 115
            ++Q F E +A  R P     GNHD                        L  A       
Sbjct: 64  ESFQSFQEIVAQLRVPYYLSLGNHDIDTLRRKGRFNRDQFIRWCQSQFPLSLAPTGYVDY 123

Query: 116 VFI-GEQWQILLLDSQ--VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGC 172
                   +++ LD+    F +P G L   QL WL   L   PE   +LL+H  P     
Sbjct: 124 SLSPLPGIRLIALDASLGRFPLPQGVLRPSQLHWLGEHLQTVPEEWLILLIHQPPF-IAP 182

Query: 173 SWLDQHSLR-------NAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCV 225
           + +D    R        A  L  +LA+   V  +L GH+H       +G   L  P    
Sbjct: 183 TQMDAVLFRKYRLLSEPASALHALLARHGRVVAVLSGHLHVPKVYVRDGIPYLTAP---- 238

Query: 226 QFKPHCSNFTLDTIAPGWRTLELHAD---GTLTTEVHRLADTRFQP 268
                     L       R  EL  +   G L     +L      P
Sbjct: 239 ---------PLVGPVSALRVFELEVNPRRGVLRYHWVKLPALDPSP 275


>UniRef50_D2EUB1 Metallophosphoesterase n=1 Tax=Bacteroides sp. D20
           RepID=D2EUB1_9BACE
          Length = 245

 Score =  159 bits (402), Expect = 1e-37,   Method: Composition-based stats.
 Identities = 58/246 (23%), Positives = 107/246 (43%), Gaps = 12/246 (4%)

Query: 20  ITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAE 79
           ++D HL       + G +T E +   ++ I+  Q + D I+ +GD++ D S ++Y     
Sbjct: 1   MSDLHLTQDG-STIWGEDTREKFIIAIDMIKKMQ-DIDAILVSGDISNDGSFSSYIFADR 58

Query: 80  GIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFG------ 133
             +S   P  W  GNHD    + +    +         I   WQI++L+S V        
Sbjct: 59  LFSSTNIPTYWSLGNHDNLDLLKNNNLLSYCKLVCEATIY-GWQIIILNSIVHDEEQPGK 117

Query: 134 -VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
               G +    +  ++ K+    ++ T+++LHH  L  G  W D   L+N  +   ++  
Sbjct: 118 NRSRGVIDIDTMIKIKNKIYTL-KKPTIVVLHHPALEIG-GWQDLKILKNRDKFREIIES 175

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADG 252
             +V+ +L GHIH+  D   NG R    P     F    SN+ +   A G+  + ++ + 
Sbjct: 176 SEYVRIVLAGHIHEFTDRTLNGIRYSTAPGLGFAFSSKLSNYEIQHGAEGFNLITINKNK 235

Query: 253 TLTTEV 258
            L  ++
Sbjct: 236 ILINKI 241


>UniRef50_D2PQZ3 Metallophosphoesterase n=1 Tax=Kribbella flavida DSM 17836
           RepID=D2PQZ3_9ACTO
          Length = 293

 Score =  159 bits (402), Expect = 1e-37,   Method: Composition-based stats.
 Identities = 66/239 (27%), Positives = 103/239 (43%), Gaps = 23/239 (9%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
           R RIL ++DT +     +   GV+   + + +L   R H  + DL+V +GD+A D S   
Sbjct: 4   RHRILHLSDTQVGRDGRDE-DGVDAVAALERMLHDAR-HLPDLDLVVVSGDIADDGSVEG 61

Query: 74  YQHFAEGIASF----RAPCVWLPGNHDFQPAMYSALQDAGISPAKRVF------------ 117
                + +A+F      P V+  GNHD +    +AL    + P                 
Sbjct: 62  CVAVRDRVAAFAAARGIPHVYCTGNHDDRSTFATALGSGHLGPDGTDLGRLMESGGPERV 121

Query: 118 ---IGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSW 174
                   +I+ LDS V G  HG LS+ QL+WL   L       T++++HH P+    S 
Sbjct: 122 AVSEVNGVRIVTLDSLVPGAAHGALSDRQLQWLANLLETPASSGTVIVVHHPPVYLESSV 181

Query: 175 -LDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCS 232
            +    LR++  L +VLA    V+ +LCGH H +L     G  +  TP    +      
Sbjct: 182 LMGTVGLRDSDRLASVLAGRD-VRAVLCGHFHLQLAATLAGVPVWVTPGVVTRIDLTTP 239


>UniRef50_A5FYX3 Metallophosphoesterase n=1 Tax=Acidiphilium cryptum JF-5
           RepID=A5FYX3_ACICJ
          Length = 274

 Score =  158 bits (401), Expect = 2e-37,   Method: Composition-based stats.
 Identities = 72/269 (26%), Positives = 109/269 (40%), Gaps = 9/269 (3%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
            G   + + Q +D HL A    A   V T         A        D +V TGDLA   
Sbjct: 5   PGAPPLLVAQFSDLHLRAPGLTANRIVETNMLAARAFAAFAALAPAPDALVITGDLADRG 64

Query: 70  SSAAYQHFAEGIAS-FRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE----QWQI 124
            + AY+  A  I    R P + +PGNHD + AM + L D   +  +            ++
Sbjct: 65  EAEAYRLLAGLIERHVRVPVILIPGNHDDRAAMRATLGDRLAADDEAGVNRPAEHLPVRL 124

Query: 125 LLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAG 184
           L LDS + G  HG L + QL +L  +LA  P R   +LLHH P+  G + +D   L NA 
Sbjct: 125 LPLDSTIGGESHGRLGDGQLRFLRDRLAADP-RPAAILLHHPPIATGIAHMDAIGLENAA 183

Query: 185 ELDTVLAKF-PHVKYLLCGHIHQELDLDWNGRRLLATPSTCV--QFKPHCSNFTLDTIAP 241
            L+  +A     V  L CGH+H+ +     G  ++  PS     QF       +   + P
Sbjct: 184 ALEAAIAPHAARVAGLWCGHVHRMIHGRLAGAPVVIAPSVAHQVQFDLTPDGPSALVLEP 243

Query: 242 GWRTLELHADGTLTTEVHRLADTRFQPDT 270
               +      + T+++  +         
Sbjct: 244 PAFVMHRWDGASFTSQMVFVDSYPGPFPF 272


>UniRef50_B8HPG6 Metallophosphoesterase n=8 Tax=Cyanobacteria RepID=B8HPG6_CYAP4
          Length = 361

 Score =  158 bits (400), Expect = 2e-37,   Method: Composition-based stats.
 Identities = 55/290 (18%), Positives = 103/290 (35%), Gaps = 49/290 (16%)

Query: 14  RVRILQITDTHLF------AQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQ 67
           + R   ++D H+        QK+   L   +  + + VL+ +   +   D ++  GDL Q
Sbjct: 4   QFRFGVLSDPHIGLAQTIRDQKNRFHLVEVSIPALEQVLQQMTAAE--VDFLLIPGDLTQ 61

Query: 68  DQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQ--------------DAGISPA 113
                 +   ++ +A    P   +PGNHD                               
Sbjct: 62  HGEPDNHAWLSDRLAQLPFPAYVIPGNHDVPVPFRDGYSIGWSEFPGYYRGYGYGNSDRL 121

Query: 114 KRVFI-GEQWQILLLDSQVFGVPH---GELSEFQLEWLERKLADAPERHTLLLLHHH--- 166
                     +++ L+S  F       G +   QL WLE  LAD+  +  L+++HH+   
Sbjct: 122 YYTCELLPGVRLIALNSNQFDHEGVQIGAVDGEQLRWLETVLADSQAKLHLVMIHHNVIE 181

Query: 167 --PLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTC 224
             P         ++ LR A  L  +L +   VK +  GH+H +   +  G   + T S  
Sbjct: 182 HLPNQTLHPMGQRYMLRQAETLLQIL-RAGGVKLVFTGHLHVQDIAEAGGIYDITTGS-- 238

Query: 225 VQFKPHCSNFTLDTIAPGWRTLELHAD--GTLTTEVH--RLADTRFQPDT 270
                      L +    +R +++  +  G +  ++   R+      PD 
Sbjct: 239 -----------LVSYPHPYRIVQIQTEPCGQIQVQIESDRVKSLPDWPDL 277


>UniRef50_D1N465 Metallophosphoesterase n=1 Tax=Victivallis vadensis ATCC BAA-548
           RepID=D1N465_9BACT
          Length = 608

 Score =  158 bits (400), Expect = 2e-37,   Method: Composition-based stats.
 Identities = 52/264 (19%), Positives = 100/264 (37%), Gaps = 33/264 (12%)

Query: 13  ARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA 72
           A +++  ++D H+         G    +  Q  +  I     + D ++ TGDL+   ++A
Sbjct: 20  AELKVAILSDIHVSP-------GNPNEQRLQQAIAEINES--DVDQVIVTGDLSNRGATA 70

Query: 73  AYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPA-KRVFIGEQWQILLLDSQV 131
                 E +     P   LPGNH+   +   AL  A +  + +  F      ++   +  
Sbjct: 71  ELTRVKELLDQLNKPYRALPGNHETNWSDSGALAFAELFRSERFAFERNGVLLIGFSTGP 130

Query: 132 FGV-PHGELSEFQLEWLERKLAD-APERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
           +     G +    + +L+  LA+ A ++  +++  H+PL           L N  E+  V
Sbjct: 131 YLKMGDGHVRAEDIAFLKDTLAERAADQKPVIVFCHYPLA--------DELSNGVEVAEV 182

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELH 249
           LA + HV  L+CGH H +   +  G   +                + D    G+  + ++
Sbjct: 183 LAPY-HVLGLVCGHTHVQFRRNIYGIDNIVCR----------PLTSNDGKTFGYNFI-VY 230

Query: 250 ADGTLTTEVHRLADTRFQPDTASE 273
            +G L     RL     + D    
Sbjct: 231 DNGKLEAWEKRL-GDPVEKDFNVR 253


>UniRef50_B9C147 Metallophosphoesterase n=1 Tax=Burkholderia multivorans CGD2M
           RepID=B9C147_9BURK
          Length = 404

 Score =  158 bits (400), Expect = 2e-37,   Method: Composition-based stats.
 Identities = 44/234 (18%), Positives = 76/234 (32%), Gaps = 14/234 (5%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
            G  R   LQI+DTH+   K       +   +    +  +        L + TGD+    
Sbjct: 140 PGAGRPLFLQISDTHIGFNKDA---NPDVAATLAQTIALVNAMPETPALAIHTGDITHLS 196

Query: 70  SSAAYQHFAEGIASFRAP-CVWLPGNHDFQP----AMYSALQDAGISPAKRVFIGEQWQI 124
               +   ++ ++  R P    +PG HD         +     A  +     F       
Sbjct: 197 KPDEFDRASQLLSGLRVPELHTVPGEHDVTDGSGAEYFRRFGRASDNRGYYSFDHAGVHF 256

Query: 125 LLLDSQVFGVPH--GELSEFQLEWLERKLADAPERHTLLLLHHHP-LPAGCSWLDQHSLR 181
           + L + +   P+  G   + QL WL + L        +++  H P       W       
Sbjct: 257 VALVNVMHFKPNGLGSFGDDQLAWLAQDLNGRTSSTPIVVFSHMPMWTIYEPW--GWGTG 314

Query: 182 NAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFT 235
           +A +   +L +F  V  +L GHIHQ +             ST        +   
Sbjct: 315 DAPQALALLRRFGSVT-VLNGHIHQIVSKVEGNVTFHTARSTAFPQPTAGNGPG 367


>UniRef50_C2FYP3 Metallophosphoesterase n=1 Tax=Sphingobacterium spiritivorum ATCC
           33300 RepID=C2FYP3_9SPHI
          Length = 317

 Score =  157 bits (398), Expect = 3e-37,   Method: Composition-based stats.
 Identities = 58/297 (19%), Positives = 105/297 (35%), Gaps = 55/297 (18%)

Query: 6   TLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDL 65
              L  +  +RI  +TD H+       L      ++   +   ++  + + D I+ TGD 
Sbjct: 33  KQKLNIKRSLRIAHLTDIHI-------LDKPEVSKAVAGIYTQLQSMKDKPDFIINTGDS 85

Query: 66  AQDQSSAAYQHFAEGIASFRAP-------CVWLPGNHDF--------------QPAMYS- 103
             D ++   +       ++               GNHD               +  +Y  
Sbjct: 86  LMDMNNQTKERIDTLWKAWDHAAATHSFAVKSCLGNHDVWYLPKEHAAYEQSSKDPLYGK 145

Query: 104 --ALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHG--ELSEFQLEWLERKLADAPERHT 159
             A+   G+  A   F  + W+ + LDS  +    G     + QL+WL  +LA    +  
Sbjct: 146 KWAMTKLGLPQAYYSFEQKGWKFIALDSINYNSEKGGYTFGQEQLDWLTEELAQTSGKTP 205

Query: 160 LLLLHHHP----------------LPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGH 203
           ++L  H P                L  G    DQH   +   + ++L + P+V+  L GH
Sbjct: 206 VVLFSHVPIISVTPLLYAAQRTPILKMGFPGGDQH--VDVMAVKSILKQHPNVRVALSGH 263

Query: 204 IHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTEVHR 260
           +H    + + G       +    +        LD  AP +  L+L+ DG+   E   
Sbjct: 264 VHYVDHVAYLGVNYYCGGAVSGNWWNG----VLDDFAPAYSILDLYEDGSSHYETIY 316


>UniRef50_UPI00016C4274 hypothetical protein GobsU_18190 n=1 Tax=Gemmata obscuriglobus UQM
           2246 RepID=UPI00016C4274
          Length = 318

 Score =  157 bits (397), Expect = 5e-37,   Method: Composition-based stats.
 Identities = 53/279 (18%), Positives = 89/279 (31%), Gaps = 45/279 (16%)

Query: 12  EARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGD--LAQDQ 69
           +  +R   ITD H+   +  +      +               + DLI+ TGD  +A D 
Sbjct: 32  KPVLRAAHITDVHITKDRDASKGVAAMFAHM------ANRRDGKPDLILNTGDAVMAVDG 85

Query: 70  S------SAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDA-------------GI 110
                  +     + + + +  AP     GNHD         +               G+
Sbjct: 86  KTTGAKAAEQVALWKQAVKAAPAPIHSCLGNHDVWDGNEPTAEVPAEKKGFGLMTEVLGM 145

Query: 111 SPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPA 170
                 F    W  + L+S      +  LS    +WL+  LA   +  T++L H   L  
Sbjct: 146 PAPYYSFDKGGWHFVSLNSMCNWPKYATLSPEHFDWLKADLAKT-KLPTVVLSHVPILSV 204

Query: 171 GCSWLDQHSLRNAG-------------ELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRL 217
                     +N                +  V  K PHVK  L GH+H     ++ G   
Sbjct: 205 TSQVYGDSCRKNNDNVVPGIWHHTDCWAISEVFRKNPHVKLCLSGHMHTCDRCEYRGVWY 264

Query: 218 LATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTT 256
           +   + C  +             P +  ++L ADGT + 
Sbjct: 265 ICGGAACGAWWNGSEY----GFPPCYGAIDLFADGTFSY 299


>UniRef50_B2IDE3 Metallophosphoesterase n=34 Tax=Bacteria RepID=B2IDE3_BEII9
          Length = 335

 Score =  156 bits (396), Expect = 5e-37,   Method: Composition-based stats.
 Identities = 44/243 (18%), Positives = 77/243 (31%), Gaps = 18/243 (7%)

Query: 13  ARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA 72
                +QI+D+H+   K       N   + +  ++ I+   H+   ++ TGD+       
Sbjct: 69  EPFTFIQISDSHIGFDKPA---NPNALATLREAIDQIKALPHKPAFMIHTGDITHLSKDK 125

Query: 73  AYQHFAEGIASFRAPCVWLPGNHDFQPA--MYSALQDAGISPA-------KRVFIGEQWQ 123
            +    + +     P   +PG HD        + L   G  P           F  +   
Sbjct: 126 EFDDADQILKEAGLPIFTVPGEHDLLDDSQGKAYLDRYGRGPLVKALGAGWYSFDQKGIH 185

Query: 124 ILLLDSQVFGVPH--GELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLR 181
            + L +         G L   QL WL   +A       +++  H PL    +        
Sbjct: 186 YIALVNVTDLKAGGLGNLGAEQLAWLAADVALLSSSTPIVVFAHIPLWTVYAEW-GWGTE 244

Query: 182 NAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCV--QFKPHCSNFTLDTI 239
           +  +    L +F  V  +L GHIHQ +             ST           +     +
Sbjct: 245 DGAKALETLKRFGSVT-VLNGHIHQIMQKVEGHVAFHTARSTAFPQPVPGTAPSPGPMKV 303

Query: 240 APG 242
            PG
Sbjct: 304 PPG 306


>UniRef50_A3ZYM0 Putative uncharacterized protein n=1 Tax=Blastopirellula marina DSM
           3645 RepID=A3ZYM0_9PLAN
          Length = 291

 Score =  156 bits (395), Expect = 7e-37,   Method: Composition-based stats.
 Identities = 52/295 (17%), Positives = 101/295 (34%), Gaps = 51/295 (17%)

Query: 4   LLTLPLAGEA--RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVA 61
           + +L  A EA    R   +TD H+  +       ++  E ++  L ++   +   ++IV 
Sbjct: 1   MPSLARAEEAAQPFRFAHLTDIHVQPE-------LSAGEGFRKCLASVNALEKRPEVIVT 53

Query: 62  TGDLAQDQSSAAYQHFAEGIA--------SFRAPCVWLPGNHDFQPAMYS---------- 103
            GD+  D  +   Q   +  +            P     GNHD     +           
Sbjct: 54  GGDMVMDIFAHNRQRADQLFSLYGDVVKGETDIPFRSCIGNHDVFGWSHRQDVKPEDAEF 113

Query: 104 ----ALQDAGISPAKRVFIGEQWQILLLDSQVF---GVPHGELSEFQLEWLERKLADAPE 156
                 +  G+      F    W+  +LD             L E Q EWL++ L + P 
Sbjct: 114 GKGLVCEKLGLEKTYYAFDQGGWRFYILDDIQMAPNNRYQAYLEEEQFEWLKKDLEEKPA 173

Query: 157 RHTLLLLHHHPLPAGCSWLDQH------------SLRNAGELDTVLAKFPHVKYLLCGHI 204
               +++ H P+    ++ +                R A +L  + +K  +VK  L GH 
Sbjct: 174 ETPAVVVSHIPIYTVSTFDNGREEDLAYRVGFSAMCREAAKLGNLFSKH-NVKLALSGHH 232

Query: 205 HQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTEVH 259
           H    +++ G   +   +    +         +    G+  ++L+ +GT   E  
Sbjct: 233 HILERIEFQGVTYICGGAVSGGWWRGPHRGVQE----GFGLVDLNPNGTFDYEYV 283


>UniRef50_Q2JHD6 Ser/Thr protein phosphatase family protein n=12 Tax=Cyanobacteria
           RepID=Q2JHD6_SYNJB
          Length = 386

 Score =  156 bits (395), Expect = 8e-37,   Method: Composition-based stats.
 Identities = 62/292 (21%), Positives = 110/292 (37%), Gaps = 49/292 (16%)

Query: 14  RVRILQITDTH------LFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQ 67
           ++R   ++D H      L+       L   +  + + VL+ +       D ++  GDL Q
Sbjct: 2   QIRFAVVSDPHVTLPSTLWDHPSRFHLVEVSIPALEQVLQHLVQL--PLDFLLLPGDLTQ 59

Query: 68  DQSSAAYQHFAEGIASFRAPCVWLPGNHDFQ--------------PAMYSALQDAGISPA 113
                 +   AE +A    P   +PGNHD                P  Y A         
Sbjct: 60  HGEPENHAWLAERLARLPFPAFVVPGNHDVPQPEASGRSIGLADFPRYYRAFGYEDGQSL 119

Query: 114 KRVFIG-EQWQILLLDSQVFGVPH---GELSEFQLEWLERKLADAPERHTLLLLHHHPLP 169
               +     +++ L+S  F       G L+  QL WLE++LA A E   LL++HH+ + 
Sbjct: 120 DYSRVLRPGIRLIGLNSNHFDAQGQLVGCLTPEQLTWLEKELAAAEEELVLLMVHHNVVE 179

Query: 170 -----AGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTC 224
                +   W  ++ L NA +L  +L  +  V+ +  GH+H +      G   + T S  
Sbjct: 180 HLRGQSLHPWGRRYMLENASQLRRLLQAY-GVQLVFTGHLHIQHIARRGGVYDITTGS-- 236

Query: 225 VQFKPHCSNFTLDTIAPGWRTLELHADG----TLTTEVHRLADTRFQPDTAS 272
                      L +    +R +E+ +D      +  + +R+      PD  +
Sbjct: 237 -----------LVSFPHPYRLVEIRSDRETGIQVHIQSYRVGSLPDWPDLQA 277


>UniRef50_B9K806 Metallophosphoesterase n=1 Tax=Thermotoga neapolitana DSM 4359
           RepID=B9K806_THENN
          Length = 355

 Score =  156 bits (394), Expect = 1e-36,   Method: Composition-based stats.
 Identities = 45/239 (18%), Positives = 84/239 (35%), Gaps = 17/239 (7%)

Query: 34  LGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPG 93
              N+  ++  ++ A+          + TGD+  D S   +  + + +  F+ P + +PG
Sbjct: 57  DNKNSISTFSKLISAVN-EDPVVSFAINTGDMVFDGSVFKWGLYLKQLKRFKVPVLHVPG 115

Query: 94  NHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLAD 153
           NHD      + L      P    F       ++L++         +  +QL WLE +L  
Sbjct: 116 NHDLADDPGNYL--KIFGPLYYSFHVGNSYFIVLNNA----NEKCVDSYQLAWLEGELEK 169

Query: 154 APERHTLLLLHHHPLPAGC----SWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELD 209
           +       +  H P+               L+NA  L  +L K+  +  +  GHIH    
Sbjct: 170 SRSYKYRFVFMHVPIYDPRVKKQPGHSMKDLKNALTLLNILKKYD-ITMVFAGHIHGYFR 228

Query: 210 LDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTEVHRLADTRFQP 268
            +WNG   + T                +     +  + +   G +  EV +L    F  
Sbjct: 229 GEWNGVPYIITGGAG----AELFGTNPEHYFYHFIKVHVSPKG-VNYEVIKLPTPDFNI 282


>UniRef50_A9APX8 Metallophosphoesterase n=4 Tax=Burkholderia RepID=A9APX8_BURM1
          Length = 312

 Score =  156 bits (394), Expect = 1e-36,   Method: Composition-based stats.
 Identities = 43/233 (18%), Positives = 76/233 (32%), Gaps = 12/233 (5%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
            G  R   LQI+DTH+   K       +   +    +  +        L + TGD+    
Sbjct: 48  PGAGRPLFLQISDTHIGFNKDA---NPDVAATLAQTIALVNAMPETPALAIHTGDITHLS 104

Query: 70  SSAAYQHFAEGIASFRAP-CVWLPGNHDFQP----AMYSALQDAGISPAKRVFIGEQWQI 124
               +   ++ ++  R P    +PG HD         +     A  +     F       
Sbjct: 105 KPDEFDRASQLLSGLRVPELHTVPGEHDVTDGSGAEYFRRFGRASDNRGYYSFDHAGVHF 164

Query: 125 LLLDSQVFGVPH--GELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRN 182
           + L + +   P+  G   + QL WL + L        +++  H P+             +
Sbjct: 165 VALVNVMHFKPNGLGSFGDDQLAWLAQDLNGRTSSTPIVVFSHMPMWTIYEPW-GWGTGD 223

Query: 183 AGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFT 235
           A +   +L +F  V  +L GHIHQ +             ST        +   
Sbjct: 224 APQALALLRRFGSVT-VLNGHIHQIVSKVEGNLTFHTARSTAFPQPTAGNGPG 275


>UniRef50_Q6ACA7 Putative uncharacterized protein n=1 Tax=Leifsonia xyli subsp. xyli
           RepID=Q6ACA7_LEIXX
          Length = 280

 Score =  155 bits (392), Expect = 2e-36,   Method: Composition-based stats.
 Identities = 60/202 (29%), Positives = 89/202 (44%), Gaps = 11/202 (5%)

Query: 13  ARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA 72
           AR+RIL ++DTHL          V+T  +   VL          D++ A+GDL+ D S A
Sbjct: 3   ARLRILHLSDTHLCGDGRLHYGMVDTLAALDRVLAHASSLD-AVDMVAASGDLSDDGSPA 61

Query: 73  AYQHFAEGIASF----RAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLD 128
           +Y+   E +  +     A   +  GNHD   A  S L      P +R      ++IL +D
Sbjct: 62  SYRLLQERLEPWAAERGAVVAYAMGNHDLPDAFESVL-----GPRERALDANGFRILTVD 116

Query: 129 SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
           + V    +G +   QL+ L   LA+  E  T ++LHH P P      D   L +   L  
Sbjct: 117 TTVPCAGYGRVDTAQLDRLSEALAEPSEHGTAIVLHHPPAPPTTRLFDTLRLVDPEPLLE 176

Query: 189 VLAKFPHVKYLLCGHIHQELDL 210
           V +    V+ +L GH H  L  
Sbjct: 177 VCSA-GDVRLILAGHYHHALVT 197


>UniRef50_C5PKR3 Putative uncharacterized protein n=2 Tax=Sphingobacterium
           spiritivorum RepID=C5PKR3_9SPHI
          Length = 627

 Score =  154 bits (391), Expect = 2e-36,   Method: Composition-based stats.
 Identities = 45/251 (17%), Positives = 92/251 (36%), Gaps = 34/251 (13%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
             R   +TDTH+         G    +  +  ++ +   Q + D ++ +GD+ +  + A 
Sbjct: 31  SFRFAHVTDTHVG--------GATGADDLRRTVKDLNAQQ-QLDFVILSGDITEFGADAE 81

Query: 74  YQHFAEGIASFRAPCVWLPGNHD--FQPAMYSALQDAGISPAKRVFIGEQWQILLLDS-Q 130
            +   + + S + P   +PGNHD  +     +  +          F  + +  +  +S  
Sbjct: 82  LRLAKQILDSLQLPWYVIPGNHDGNWSENGANTFRKVFGGETFF-FRHKGYMFMGTNSGP 140

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERH-TLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
              +  G++    L W++      P+    L+ ++H+P           SL N  E    
Sbjct: 141 NMRMSPGQIPRENLVWMDSVFKANPDTQTPLIYINHYP--------QDSSLNNWFEAINR 192

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELH 249
           + K  +V+   CGH H  +  +W G   +   S          N        G+  + + 
Sbjct: 193 VKKR-NVQLAFCGHGHANVKYNWEGIPGIMGRS----------NLRAKDSIGGYNIVTI- 240

Query: 250 ADGTLTTEVHR 260
            DG    +V +
Sbjct: 241 GDGKAVYQVKK 251


>UniRef50_C6VU97 Metallophosphoesterase n=1 Tax=Dyadobacter fermentans DSM 18053
           RepID=C6VU97_DYAFD
          Length = 244

 Score =  154 bits (391), Expect = 2e-36,   Method: Composition-based stats.
 Identities = 62/247 (25%), Positives = 102/247 (41%), Gaps = 19/247 (7%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           RI QITD HL  +   A  G +T  + + +L+ +         I+ TGD+    + A+YQ
Sbjct: 3   RIAQITDIHLMEEW-SAQNGADTDTNLKLILQDVGARGIRD--IIFTGDI---GNPASYQ 56

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGIS---PAKRVFIGEQWQILLLDSQVF 132
            F   +  F      +PGNHD    +    Q A +              ++ + LDS   
Sbjct: 57  RFFALMKDFD--FTIIPGNHDKFADIRPHYQPAYLEGKSEMFHAVEETHFKYIFLDSSSD 114

Query: 133 GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAK 192
                 +SE QL WLE +L     RH LL +HH  L    +   ++ L N   +  +L +
Sbjct: 115 S-----VSEMQLRWLENEL--VTTRHVLLFIHHPVLQVLTAVDFKYPLLNRAAVKELLVR 167

Query: 193 FPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADG 252
                 +  GH H +            TP+  VQ + +     + +   G+R +EL  + 
Sbjct: 168 SDREITIFSGHYHTDDFTKEENLTQYVTPAASVQMEKNPLEIVVHSRYYGYRIIEL-EER 226

Query: 253 TLTTEVH 259
           +++T V 
Sbjct: 227 SVSTHVV 233


>UniRef50_B6YTV2 Metallophosphoesterase n=2 Tax=Thermococcus RepID=B6YTV2_THEON
          Length = 545

 Score =  154 bits (390), Expect = 3e-36,   Method: Composition-based stats.
 Identities = 37/237 (15%), Positives = 87/237 (36%), Gaps = 13/237 (5%)

Query: 29  KHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPC 88
            H +  G    E +  ++E I  ++ +   I+ +GDL    +   +    +    +  P 
Sbjct: 320 DHRSDGGTEVPEVFLKIMEEINNNEEDAVFIIDSGDLIYSGTVDQWAALLDEW-EWEKPI 378

Query: 89  VWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLE 148
              PGNH+++    +        P    F+   +  + +++         LS+ Q  WL+
Sbjct: 379 FIAPGNHEYRGEGINIYH-MLFGPTDYSFVLGDYYYIFMNNIENDYS---LSDEQWVWLQ 434

Query: 149 RKLADAPE--RHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQ 206
            +L  A E  +  ++++H  P+          +  +   L  ++ ++ +   +  GHIH 
Sbjct: 435 DELEKAEEMGKRPVIVMHAPPVDPRPEGDHGMNPTDGKRLLQLMKEY-NAFGIF-GHIHM 492

Query: 207 ELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTEVHRLAD 263
               + +G   +   +              D     +  L +  DG++  E  ++  
Sbjct: 493 FWYGEKDGAEFVVAGAAGAPLYASPDEGGFDH----YTRLFMATDGSIGVEPVKVEP 545


>UniRef50_B3C782 Putative uncharacterized protein n=2 Tax=Bacteroides
           RepID=B3C782_9BACE
          Length = 618

 Score =  153 bits (388), Expect = 5e-36,   Method: Composition-based stats.
 Identities = 41/263 (15%), Positives = 92/263 (34%), Gaps = 34/263 (12%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
           + +       ++D HL +            +  +  +E I     + D  + +GD+ +  
Sbjct: 13  SNQRAFTFAWLSDVHLNS-------FAYAEDDLRQSIEDINA-NPDVDFTILSGDVTEFG 64

Query: 70  SSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYS-ALQDAGISPAKRVFIGEQWQILLLD 128
            +  +    + +  FR P   +PGNHD   +     + D     +   +  +  + +   
Sbjct: 65  DTKEFYLLQDILKDFRKPYFLIPGNHDVNWSENGCTMFDKIFQASHFCYDWQGVRFIGCG 124

Query: 129 ---SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGE 185
              S   G PH  +   ++ WL+  +   P +  ++ ++H PL           L N  E
Sbjct: 125 AGPSLRMGPPH--IPREEILWLDSIVRATPAKQPIIFINHFPL--------NQDLSNWYE 174

Query: 186 LDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRT 245
           +  +L K  +++ +L GH+H     D  G   +   S          +   +    G+  
Sbjct: 175 VIDIL-KTRNIQAVLGGHLHVNHAYDAEGIPAVIGRS----------SLRREDTIGGYNL 223

Query: 246 LELHADG-TLTTEVHRLADTRFQ 267
           + L  +       + ++      
Sbjct: 224 VHLRGNTLEFNERIIKVETRPAW 246


>UniRef50_C8QH10 Metallophosphoesterase n=3 Tax=Enterobacteriaceae
           RepID=C8QH10_9ENTR
          Length = 240

 Score =  153 bits (387), Expect = 5e-36,   Method: Composition-based stats.
 Identities = 58/251 (23%), Positives = 93/251 (37%), Gaps = 15/251 (5%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + + QI+D H            +  + +   L  +     +   +V TGDL  +Q  A Y
Sbjct: 1   MLVAQISDIHASPDN-------DNLQRFDKALAWLDQLNPDV--LVLTGDLIDNQWLAGY 51

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQD-AGISPAKRVFIGEQWQILLLDSQVFG 133
              AE ++  + P   LPGN D +  M +     A        +     ++L LDS + G
Sbjct: 52  ALIAERLSQKKWPSRVLPGNSDDRRQMRAVWGATAADEFLHFNYDAGDLRLLGLDSTLVG 111

Query: 134 VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKF 193
           V  G +    + WLE++L D      LL LHHH   +G   LD+       EL  ++   
Sbjct: 112 VTAGSV-VNHIAWLEQQLRDIHTSPALLFLHHHVFASGIPSLDKTMCAGVPELAALIRHM 170

Query: 194 PH-VKYLLCGHIHQELDLDWNGRRLLATPSTC--VQFKPHCSNFTLDTIAPGWRTLELHA 250
           P  +  +  GH+H+ +     G       S C                  P    +  + 
Sbjct: 171 PGKLLAIASGHVHRPIAGALAGVPAYICGSLCPANPVWFGTDTVPPVNDPPA-LMIHRYV 229

Query: 251 DGTLTTEVHRL 261
           D  LT+    L
Sbjct: 230 DNVLTSHHVSL 240


>UniRef50_C1VB71 Predicted phosphohydrolase n=1 Tax=Halogeometricum borinquense DSM
           11551 RepID=C1VB71_9EURY
          Length = 344

 Score =  153 bits (387), Expect = 6e-36,   Method: Composition-based stats.
 Identities = 50/228 (21%), Positives = 81/228 (35%), Gaps = 24/228 (10%)

Query: 16  RILQITDTHLFAQKHEAL-LGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           RI  ++D HL         +   T    +A + AI     +  L +  GDL +D     +
Sbjct: 37  RIAVVSDPHLTPTATGTWKVYHRTETRLRAAIAAINDLNVDATLSL--GDLTRDGHPEEF 94

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQ--------PAMYSALQDAGISPAKRVFIGEQWQILL 126
               E +A    P V +PGNHD          P +                      ++ 
Sbjct: 95  DCVDELLADLDTPFVSVPGNHDVPKQWDDYEAPTVDEFGARYARGAFPFHVSVGGVDLIG 154

Query: 127 LDS-----QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCS-----WLD 176
           LD+      ++    G +    + WL+  L++      ++  HH+              D
Sbjct: 155 LDTASGDGTLYDSHEGLVPSEHVAWLDETLSEVES--PIVASHHNVFHPREHTGQFADED 212

Query: 177 QHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTC 224
            + LRNA E+  VL+       +L GHIH        G R +  P+TC
Sbjct: 213 FYQLRNADEVVEVLSSGGD-PLVLSGHIHWPATARRGGVREIIAPATC 259


>UniRef50_C7PMF7 Metallophosphoesterase n=1 Tax=Chitinophaga pinensis DSM 2588
           RepID=C7PMF7_CHIPD
          Length = 616

 Score =  153 bits (386), Expect = 9e-36,   Method: Composition-based stats.
 Identities = 47/264 (17%), Positives = 91/264 (34%), Gaps = 37/264 (14%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
           A +   R    +DTH+  +           E  +  +  I  +  +   ++ +GD+ +  
Sbjct: 19  AQDTLFRFALASDTHIGNKSGA--------EDLERTVLDIN-NHPDIAFVLFSGDITEFG 69

Query: 70  SSAAYQHFAEGIASFRAPCVWLPGNHD--FQPAMYSALQDAGISPAKRVFIGEQWQILLL 127
           S    Q     I+    P   +PGNHD  +  +  +   +         F  + +  L  
Sbjct: 70  SDEEIQLAKSIISKLNKPWYIVPGNHDSNWSESGCNTFLNVFGGET-FSFRYKGYWFLGT 128

Query: 128 DSQVFG--VPHGELSEFQLEWLERKLADAPERH-TLLLLHHHPLPAGCSWLDQHSLRNAG 184
            S      +  G++    L WL+ +L    ++   ++ ++H+P           +L N  
Sbjct: 129 -SCGPNMRMGPGQVPREDLTWLKEQLRKEKDKKVPVIFVNHYP--------QDSALNNWY 179

Query: 185 ELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWR 244
           E   +L    ++K +LCGH H     D+ G   +   S          N         + 
Sbjct: 180 EQLEMLKDR-NLKAILCGHGHANRKYDFEGIPGIMCRS----------NLRAKADTGAYN 228

Query: 245 TLELHADGTLTTEVHRLADTRFQP 268
            + L  D  +  E  R+      P
Sbjct: 229 IISLVHDSLVFNE--RVPGGATLP 250


>UniRef50_D1VKL8 Metallophosphoesterase n=1 Tax=Frankia sp. EuI1c RepID=D1VKL8_9ACTO
          Length = 325

 Score =  152 bits (385), Expect = 9e-36,   Method: Composition-based stats.
 Identities = 44/231 (19%), Positives = 81/231 (35%), Gaps = 10/231 (4%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
           A +A +R +Q++D+H+           +   S+   +  +       D ++ TGDL    
Sbjct: 63  ADQATLRFVQVSDSHIGFHGTA---NPDVTGSFARAIAQVNALPDRPDFVMHTGDLTHLS 119

Query: 70  SSAAYQHFAEGIASFRA-PCVWLPGNHDFQP----AMYSALQDAGISPAKRVFIGEQWQI 124
           + A +   ++ +   RA     +PG HD       A  +A            F  +   +
Sbjct: 120 TPAQFDQVSQMMRGLRAGAVHTVPGEHDSVDDGGRAYRAAFGAGSRGDGWYSFDVKGVHV 179

Query: 125 LLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAG 184
           L L + +     G L   QL ++ + +A       +L+  H PL A           +A 
Sbjct: 180 LALVNTLSLEKLGHLGADQLAFIRQDVAGLSSDTPILVFSHIPLFAMYPTW-GWGTDDAV 238

Query: 185 ELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFT 235
           +  + L +F  V   L GH+HQ            +  +T            
Sbjct: 239 QALSYLRRFSSVT-CLNGHVHQLFSRTEGNVVFRSATTTAYPLPKPGDGPA 288


>UniRef50_C7PXI9 Metallophosphoesterase n=2 Tax=Actinomycetales RepID=C7PXI9_CATAD
          Length = 314

 Score =  151 bits (382), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 36/226 (15%), Positives = 78/226 (34%), Gaps = 10/226 (4%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +R +Q++D+H+           +   S+   ++ +       + ++ TGDL    ++A +
Sbjct: 57  LRFVQVSDSHIGFTGPA---NTDVTASFTEAIDQVNSLGFRPNFVMHTGDLTHLSTAAQF 113

Query: 75  QHFAEGIASFRA-PCVWLPGNHDFQP----AMYSALQDAGISPAKRVFIGEQWQILLLDS 129
               + ++  R      +PG HD       A                F       + L +
Sbjct: 114 DQVKQMLSEVRTERVFTVPGEHDSVGDSGRAYRQTFGAGTTGDGWYSFDTHGVHFIALVN 173

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
            +     G L   Q++++ + +A       +++  H PL A        S  ++ ++  +
Sbjct: 174 TLSLEKLGHLGNDQIDFVRKDVAGLSSDTPIVVFSHIPLFAMYPAW-GWSTDDSLQVLAL 232

Query: 190 LAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFT 235
           L +F  V   L GH+HQ            +  +T            
Sbjct: 233 LRRFASVT-CLNGHVHQLFSKTEGNVTFHSATTTAYPLPAPGKAPA 277


>UniRef50_Q46D43 3,5-cyclic-nucleotide phosphodiesterase n=8 Tax=Archaea
           RepID=Q46D43_METBF
          Length = 230

 Score =  151 bits (382), Expect = 3e-35,   Method: Composition-based stats.
 Identities = 49/222 (22%), Positives = 89/222 (40%), Gaps = 18/222 (8%)

Query: 45  VLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAP-CVWLPGNHDFQPAMYS 103
           +LE I     +   IV TGDL ++  +A Y    + I        V +PGNHD + A Y 
Sbjct: 8   MLENINRSSPDI--IVITGDLTENGLAAEYNGAKKFIDRIECKNKVIVPGNHDSRNAGYL 65

Query: 104 ALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLL 163
             +D   + +       +  ++ LDS    +  G +      W+E   +       +  L
Sbjct: 66  FFEDLFKTRS-TSGQFGEITVVGLDSSQPELDEGHIGRENYNWIENTFSV--NGFKVFAL 122

Query: 164 HHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPST 223
           HHH +P   +    + L +AG++  +L +   V  +LCGH H       N   +++  + 
Sbjct: 123 HHHLIPIPRTGRGNNVLVDAGDVLELLDR-SGVNLVLCGHWHIPWVWRLNDMLVISAGTV 181

Query: 224 CVQFKPHCSNFTLDTIAPGWRTLELHAD----GTLTTEVHRL 261
           C       S+     ++  +  +E+ A          +V R+
Sbjct: 182 C-------SSKVRGKMSQCYNFIEVDAPESDCKRWHLQVCRV 216


>UniRef50_C7NWB5 Metallophosphoesterase n=1 Tax=Halomicrobium mukohataei DSM 12286
           RepID=C7NWB5_HALMD
          Length = 312

 Score =  151 bits (382), Expect = 3e-35,   Method: Composition-based stats.
 Identities = 59/265 (22%), Positives = 102/265 (38%), Gaps = 44/265 (16%)

Query: 16  RILQITDTHL-FAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           R   + D H+   +   + L  +T +  +A +  I     + D +++ GDL +D     Y
Sbjct: 23  RFAVLADPHVSTRESGTSKLFEHTLDHLEAAVADIGRR--DVDAVLSPGDLTKDGEPWNY 80

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQ-------PAMYSALQD-AGISPAKRVFIGEQWQILL 126
               E ++    P   +PGNHD         P    A  D  G              ++ 
Sbjct: 81  DAVDEALSELDVPFYAVPGNHDVPKVRDEHDPLSVEAFADRYGPGELPYHAEVGGLDVIG 140

Query: 127 LDSQ-----VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHS-- 179
           L++      ++    G ++E  L+WL+  LA+A     ++LLHH+ LP+    +D H   
Sbjct: 141 LNTAGTADRLYESHEGRVTEATLDWLDETLAEAE--TPVVLLHHN-LPSVSDQIDAHREI 197

Query: 180 ---------LRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPH 230
                    + +A  L   LA     + LL GH H     +++G R +A P+TC      
Sbjct: 198 EPEMVEIPAMADADPLAETLAD-GGAQLLLSGHYHLPATGEYHGLREIAAPTTC------ 250

Query: 231 CSNFTLDTIAPGWRTLELHADGTLT 255
                  +    +   E   +GT  
Sbjct: 251 -------SFPQSYLLCETTPEGTTV 268


>UniRef50_A6CD50 Cyclic 3',5'-adenosine monophosphate phosphodiesterase n=1
           Tax=Planctomyces maris DSM 8797 RepID=A6CD50_9PLAN
          Length = 301

 Score =  151 bits (381), Expect = 3e-35,   Method: Composition-based stats.
 Identities = 63/260 (24%), Positives = 98/260 (37%), Gaps = 21/260 (8%)

Query: 20  ITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLA-QDQSSAAYQHFA 78
           + DTH+  +KH     + T    + ++  +     +   ++  GDLA +D     Y+HFA
Sbjct: 44  LNDTHIG-EKHPPKSPIPTH--LREIVTELVELPQKPACVLINGDLALRDGQPGDYRHFA 100

Query: 79  EGIASFR---APCVWLPGNHDFQPAMYSALQDAGISPAK------RVFIGEQWQILLLDS 129
             I   +          GNHD +   Y  +Q+   S          V   +     LLDS
Sbjct: 101 SLIQPLQEAKIDTHLTLGNHDERDVFYEVMQEQRPSAPPVKSRHISVVQTKFANFFLLDS 160

Query: 130 -QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
                V  G L + Q  WL   L    ++  +++ HH+P   G        L ++ EL  
Sbjct: 161 LHKTMVTQGTLGKEQRSWLANALDAHADKPAIIVTHHNPRLGGDPVHFPGGLTDSEELWE 220

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLEL 248
           +L   P VK  + GHIH   +    G  +L TP+T     P       D    GW   +L
Sbjct: 221 LLVSRPQVKAYIHGHIHDRGNAQHKGIHILNTPATSYVANP-------DHSTTGWTIAQL 273

Query: 249 HADGTLTTEVHRLADTRFQP 268
              G   T    + D  +  
Sbjct: 274 TPTGVTLTTRTNIEDHAWNR 293


>UniRef50_B4D428 Metallophosphoesterase n=1 Tax=Chthoniobacter flavus Ellin428
           RepID=B4D428_9BACT
          Length = 303

 Score =  151 bits (381), Expect = 3e-35,   Method: Composition-based stats.
 Identities = 59/246 (23%), Positives = 94/246 (38%), Gaps = 22/246 (8%)

Query: 18  LQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLA-QDQSSAAYQH 76
             ++DTH+ A    A   VN  +  +  +  +R        ++  GD A     +  Y  
Sbjct: 43  ALLSDTHVAADATLARFDVNMADHLRNAVAGVRALSSPPAGVIVNGDCAFNHGLAEDYAT 102

Query: 77  FAEGIASF---RAPCVWLPGNHDFQPAMYSALQDAGISPAK------RVFIGEQWQILLL 127
           F   +        P     GNHD +   ++A++DA  +P         +         +L
Sbjct: 103 FTGLLHPLSEAGLPLHLSLGNHDDREVFWNAIKDARQTPPPLASRQVSIVEAGHANWFML 162

Query: 128 DSQ-VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGEL 186
           DS  V     G L + Q  WL + L    ++  L+++HH P+        +  L +  EL
Sbjct: 163 DSLDVTNKTPGVLGDEQRAWLSKALDARTDKPALVVVHHDPMLIEGK---KTGLLDTAEL 219

Query: 187 DTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTL 246
             +L    HVK L+ GH H     D +G  L+  P+    FK             GW   
Sbjct: 220 LAILKPRSHVKALIFGHTHTWRLTDHDGLHLVNLPAVGYPFKKEEVT--------GWVDC 271

Query: 247 ELHADG 252
           +L ADG
Sbjct: 272 QLRADG 277


>UniRef50_UPI0000588F73 PREDICTED: hypothetical protein n=2 Tax=Strongylocentrotus
           purpuratus RepID=UPI0000588F73
          Length = 307

 Score =  149 bits (377), Expect = 8e-35,   Method: Composition-based stats.
 Identities = 50/280 (17%), Positives = 93/280 (33%), Gaps = 22/280 (7%)

Query: 12  EARVRILQITDTHLFAQKHEALLGVNTWES----YQAVLEAIRPHQHEFDLIVATGDLAQ 67
           +     +Q  D         A     TW++     +  + AI     +    V  GDL  
Sbjct: 24  KGPFCFIQGADPQYGMMDDMANKTPITWKAEIELTRKAVAAINKMNPKPKFFVVCGDLVH 83

Query: 68  D--QSSAAYQHFAEGIASF-----RAPCVWLPGNHDFQPAMYSALQDAG---ISPAKRVF 117
                +   +  A+ +  F       P V + GNHD                       F
Sbjct: 84  AFPGDAQKEEQEADFLREFAKVDPSIPLVCVCGNHDVGNTPTRKSIQHFRNKFGDDYFGF 143

Query: 118 IGEQWQILLLDSQVFGVPH--GELSEFQLEWLERKLADAPE---RHTLLLLHHHPLPAGC 172
                + L+L+SQ++       EL + Q  WL+ +L  A     +H +L  H        
Sbjct: 144 WAGGVRCLVLNSQLYEDASMVEELKKEQDVWLDAELDAAKSSGCKHLVLFQHIPWFLNTP 203

Query: 173 SWLDQHSLRNAGELDTVLAKF--PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPH 230
              +++   +      +L KF    V  + CGH H+     + G   + T +       +
Sbjct: 204 DEENEYFNIDQDIRMPMLDKFLAAGVSTIFCGHYHRNAGGSYKGMEEVVTSAMGCTLSEN 263

Query: 231 CSNFTLDTIAPGWRTLELHADGTLTTEVHRLADTRFQPDT 270
            S   +     G R +++H   +++ + + + D     D 
Sbjct: 264 TSVLEIGDTPSGLRVVKVHE-KSISHQYYGMDDIPATIDL 302


>UniRef50_C8WD30 Metallophosphoesterase n=5 Tax=Alphaproteobacteria
           RepID=C8WD30_ZYMMN
          Length = 314

 Score =  149 bits (377), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 49/280 (17%), Positives = 84/280 (30%), Gaps = 45/280 (16%)

Query: 8   PLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQ 67
           PL        + ITDTHL  + + A                ++  Q   D  +  GD   
Sbjct: 35  PLRSHQSFTFVFITDTHLQPELNGAEGCHE---------AFLKARQFPADFAIHGGDHVF 85

Query: 68  DQ-----SSAAY--QHFAEGIASFRAPCVWLPGNHDFQPAMYSA------------LQDA 108
           D      + A      +       R P     GNHD       +                
Sbjct: 86  DALGVNANRATMLADLYKRTADDLRLPVYNTMGNHDCFGIYKESGAQPTDPFYGKKYFQD 145

Query: 109 GISPAKRVFIGEQWQILLLDS---QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHH 165
                   F  +    ++LDS          G +   Q  WL R LA  P    +++  H
Sbjct: 146 NFGQTYYSFDHKGVHFVILDSIGITEDRSYEGRVDAEQFNWLSRDLAAQPVGTPIIVSTH 205

Query: 166 HPL-------PAGCSWLDQHSLR--NAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRR 216
            P+           + +  HSL   NA ++  +   + +V  +  GH H    ++W+G  
Sbjct: 206 IPIMNAIDYASVPLNKMKHHSLSVINAADILELFDHY-NVIGVFQGHTHVVERVEWHGVP 264

Query: 217 LLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTT 256
            +   S C  +              G+  +++     +  
Sbjct: 265 YITGGSVCGNWWHGTRY----GTPEGFMVVKVEKGKVIPH 300


>UniRef50_D0TER0 Metallophosphoesterase n=2 Tax=Bacteroidales RepID=D0TER0_9BACE
          Length = 276

 Score =  149 bits (377), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 49/262 (18%), Positives = 86/262 (32%), Gaps = 25/262 (9%)

Query: 5   LTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGD 64
           +T  LA       +Q++D      +        T    + V+ AI         +V TGD
Sbjct: 15  ITKTLAQSESFYFIQLSDPQFGMLEKNKSFSQETM-IMEKVIAAINNLNP--AFVVITGD 71

Query: 65  LAQDQSS----AAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSA---LQDAGISPAKRVF 117
           +  D         ++   + I     P   LPGNHD                       F
Sbjct: 72  MVNDGKDQKQIDEFKRVCKLIKK-SIPVYVLPGNHDLSQQCTDESISNYMDEYGYDCFSF 130

Query: 118 IGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSW--- 174
                  + L++ V      E  + QL WLE+ L ++ + +  +L  H+P     S    
Sbjct: 131 QVNNSCFIGLNTPVIFANREEKEKSQLIWLEKILENSQKCNHRILFGHYPFFVKESNEAN 190

Query: 175 -LDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSN 233
             +   L        +++K+  V  +  GH+H      +    +  T S C         
Sbjct: 191 RYENIPLEKRKTYLDLMSKY-RVSNMFAGHLHYNAMSSYEDFNITITNSICT-------- 241

Query: 234 FTLDTIAPGWRTLELHADGTLT 255
             L     G R ++++ D  + 
Sbjct: 242 -PLGKDRIGIRIIKVYPDKVVH 262


>UniRef50_A7C221 Metallophosphoesterase n=1 Tax=Beggiatoa sp. PS RepID=A7C221_9GAMM
          Length = 356

 Score =  149 bits (376), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 46/241 (19%), Positives = 80/241 (33%), Gaps = 31/241 (12%)

Query: 13  ARVRILQITDTHLFAQKHEAL-LGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
             +R   I+D H+  +    + +   + E  +  +  I     E   ++  GDL QD   
Sbjct: 41  DSIRFAVISDPHIDIKGKNRVKMSAFSVECLRKTINDINQE-PELAFVLIVGDLLQDGEW 99

Query: 72  AAYQHFAEGIASFRAPCVWLPGNHDFQPAMY---------------SALQDAGI---SPA 113
              +     +     P   + GNHDF P                        G       
Sbjct: 100 ENARVAKNLLDQLLVPYYIICGNHDFMPTFQKQRDGFHYLSVEEFVKFFNGHGFDNSGKR 159

Query: 114 KRVFIG-EQWQILLLDSQVFGVPH---GELSEFQLEWLERKLADAPERHTLLLLHHHPL- 168
                     +++ LD+ +   P    G L E QL WL+++L +      L+ +HH  + 
Sbjct: 160 YYAHRIKPGLRLIGLDACLPKEPEKWGGLLPEEQLTWLDKQLTNHANERHLIFIHHSLIR 219

Query: 169 ----PAGCSWLDQHSLRNAGELDTVLAKFPH-VKYLLCGHIHQELD-LDWNGRRLLATPS 222
                          + N  E+  +L+        ++ GH H  L+  + NG      PS
Sbjct: 220 WSTDELPDGPKQWFCIDNDIEVKNLLSSHAKTAPIVINGHRHTGLNMKEVNGVNYFTMPS 279

Query: 223 T 223
           T
Sbjct: 280 T 280


>UniRef50_UPI0001744C1C hypothetical protein VspiD_21990 n=1 Tax=Verrucomicrobium spinosum
           DSM 4136 RepID=UPI0001744C1C
          Length = 292

 Score =  148 bits (375), Expect = 2e-34,   Method: Composition-based stats.
 Identities = 53/290 (18%), Positives = 85/290 (29%), Gaps = 41/290 (14%)

Query: 4   LLTLPLAGEARVRILQITDTHLFA-QKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVAT 62
           +L         +RI  +TD H    +  +      T    +  +      +     ++  
Sbjct: 22  MLATDETASPLLRIGLLTDLHYGDKEPTKTRYYRETPGKLKEAVAKFNEIKP--AFVIEL 79

Query: 63  GDLAQDQS--SAAYQHFAEG---IASFRAPCVWLPGNHDFQPAMYSALQDAGIS--PAKR 115
           GDL               E     A    P  ++ GNH               +      
Sbjct: 80  GDLIDQAPTVEQEIAWLEEIDMIYAGLTCPRHYVLGNHCVATLTKEEFAQHSGASKKPHY 139

Query: 116 VFIGEQWQILLLDSQ--VFGVPHGE---------LSEFQLEWLERKLADAPERHTLLLLH 164
            F       ++LD+     G P+G          + E +LEWL + LA       +++  
Sbjct: 140 SFDQNGVHFVVLDACYRSDGAPYGRNNADWKDANVPEAELEWLRKDLAATAG--PVVVFA 197

Query: 165 HHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTC 224
           H  L         HS+ NA  +  VL     V  +  GH H+    +  G       +  
Sbjct: 198 HQRLDEAAP----HSVLNATAVRKVLEDSGKVLAVFQGHSHKNDYQEIQGIHYCTLVAL- 252

Query: 225 VQFKPHCSNFTLDTIAPGWRTLELHADGTLTTEVHRLADTRFQPDTASEG 274
                            G+  LE+  D +L     RL   R Q D    G
Sbjct: 253 --------IEGSGADNNGYAVLEVMPDRSL-----RLQGFRQQVDQKWAG 289


>UniRef50_A1ZMS0 Putative uncharacterized protein n=1 Tax=Microscilla marina ATCC
           23134 RepID=A1ZMS0_9SPHI
          Length = 221

 Score =  148 bits (375), Expect = 2e-34,   Method: Composition-based stats.
 Identities = 54/250 (21%), Positives = 108/250 (43%), Gaps = 30/250 (12%)

Query: 12  EARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
           +  +RI+QITD +L A  H     V   + ++ +L  I    H  DL++ T ++ Q + +
Sbjct: 2   DDTIRIVQITDPYLLANIH--YPEVLPIQVFENILTHINLLPHPPDLLILTSEVLQQRRN 59

Query: 72  AAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQV 131
              +     +     P  W+   H+                    F  +    ++L+S  
Sbjct: 60  DTLR----LLQRLDIPFYWVA--HE----------------QNASFNVKGTHFIMLNSCS 97

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLA 191
                G L    L++L+  L ++     ++ L HHPL        + +L++AG+  ++L 
Sbjct: 98  KNHSQGYLGNDTLDFLQNDLENSWAYPCIVTLRHHPLAIRTLTPPKDTLKDAGQFLSILD 157

Query: 192 KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHAD 251
           +F H+K +L GHIH +  L+ N     A+P+ C     + +      +   +R L+L ++
Sbjct: 158 QFYHIKAVLFGHIHHDFMLERNDIWFFASPAICPISPNNPA------VVFQYRLLDLTSE 211

Query: 252 GTLTTEVHRL 261
           G +   + ++
Sbjct: 212 GEVEVSLMKV 221


>UniRef50_A7HEA8 Metallophosphoesterase n=1 Tax=Anaeromyxobacter sp. Fw109-5
           RepID=A7HEA8_ANADF
          Length = 382

 Score =  148 bits (373), Expect = 2e-34,   Method: Composition-based stats.
 Identities = 49/254 (19%), Positives = 91/254 (35%), Gaps = 33/254 (12%)

Query: 1   MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV 60
           + + L L L  +   +   I+DTHL+ +            + + V+      +   D ++
Sbjct: 53  LINTLDLALGAQQGFKFAWISDTHLYPKDVNTRFVDKAVRATKEVI----AMRPAADFLM 108

Query: 61  ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE 120
             GDLAQ           E +   +    ++PG HD+   M               F  +
Sbjct: 109 FGGDLAQLGDPVELDLGNEILKEVKIKKYFIPGEHDWYLDMGQRWTKL-FGQPNWTFDHK 167

Query: 121 QWQILLLDSQVFGVPH------------GE--------------LSEFQLEWLERKLADA 154
             + + LD+   G  +            G               +   QLEWL + L+D 
Sbjct: 168 GVRFVGLDTVSRGPDYWTAKKMSPKERMGHMATLDGSVAGAWAGVGRDQLEWLGKTLSDW 227

Query: 155 PERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNG 214
            +   +++  H+PL       +   +R+  E++ VL  F +V  +  GH HQ L  +   
Sbjct: 228 RKDAPVVVFSHNPLYEYYPPWN-FWVRDWREVNEVLRPFTNVTNI-HGHTHQVLYNELGK 285

Query: 215 RRLLATPSTCVQFK 228
            R +   +T   + 
Sbjct: 286 MRSIGMLATSWPWP 299


>UniRef50_B6IMU0 3',5'-cyclic-nucleotide phosphodiesterase, putative n=1
           Tax=Rhodospirillum centenum SW RepID=B6IMU0_RHOCS
          Length = 286

 Score =  147 bits (372), Expect = 4e-34,   Method: Composition-based stats.
 Identities = 51/264 (19%), Positives = 88/264 (33%), Gaps = 24/264 (9%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           RI  I+D H                + +  L A        DLIV +GDL Q    + ++
Sbjct: 3   RIAHISDLHFGRIDPA------VVAALRDDLAA-----QAPDLIVVSGDLTQRARPSQFR 51

Query: 76  HFAEGIASFRAPCVWLPGNHDFQP-AMYSALQDAGISPAKRV-------FIGEQWQILLL 127
                +A   AP + +PGNHD     + + L D   +  + +              +L L
Sbjct: 52  AARAFLADLPAPHMVVPGNHDLPAFNLLARLVDPLRNYRRYIAEDLDPFLNLGNLAVLGL 111

Query: 128 DSQV---FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAG 184
           ++          G +++ Q++ +   L +       ++  HHP         +  +  A 
Sbjct: 112 NTSRSLILDFAEGRVNQRQMDRILGCLRELGPEVFKVVFTHHPFLPPPDHPGRRLVGRAT 171

Query: 185 ELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWR 244
                L     V  LL GH+H+    D          S  V      ++  L      W 
Sbjct: 172 RALRALEA-AGVDLLLAGHLHRAYSGDVMSHHAHVERSILVAQASTATSTRLRNEPNAWN 230

Query: 245 TLELHADGTLTTEVHRLADTRFQP 268
            +E+    +L   +      RF P
Sbjct: 231 LIEIAPP-SLVLRLRTWEGERFMP 253


>UniRef50_A4A1K6 Ser/Thr protein phosphatase family protein (Fragment) n=1
           Tax=Blastopirellula marina DSM 3645 RepID=A4A1K6_9PLAN
          Length = 269

 Score =  147 bits (371), Expect = 4e-34,   Method: Composition-based stats.
 Identities = 51/239 (21%), Positives = 84/239 (35%), Gaps = 12/239 (5%)

Query: 7   LPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLA 66
                   + +  ++DTH+          VN   + Q  +  I     +   ++  GD A
Sbjct: 31  YAAPAAQTMTLALLSDTHIPKNAEVTAREVNMTSNLQQGVREINQLPSKPAAVLFNGDCA 90

Query: 67  Q-DQSSAAYQHFAEGIASF---RAPCVWLPGNHDFQPAMYSAL----QDAGISPAKRV-- 116
                 A Y +FA+ I      +       GNHD  PA Y AL     +  +  +K V  
Sbjct: 91  YLSGLPADYANFAQCIQPLIDAQQELHMTMGNHDNIPAFYDALKTQRPEQPLVESKHVSI 150

Query: 117 FIGEQWQILLLDS-QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWL 175
                    LLDS     V  GEL + QL+WL  +L    ++  +++ HH          
Sbjct: 151 LETPYVNFFLLDSLMKTNVVTGELGDAQLKWLSDELDARADKPAIIMAHHTLQKVAPPEG 210

Query: 176 DQH-SLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSN 233
                + +  +   ++     VK  + GH H           L+  P++   F P   N
Sbjct: 211 KAWGGILDTAKFLELMHAKKQVKAYVFGHSHVWSHARDGDLHLINLPASAYVFNPTQPN 269


>UniRef50_C6B6U2 Metallophosphoesterase n=2 Tax=Rhizobium leguminosarum
           RepID=C6B6U2_RHILS
          Length = 250

 Score =  146 bits (370), Expect = 5e-34,   Method: Composition-based stats.
 Identities = 63/256 (24%), Positives = 98/256 (38%), Gaps = 20/256 (7%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + + QI+D H           +++  + +  +  ++  + +   +V TGDL  DQ    Y
Sbjct: 1   MLVAQISDIHAGPD-------LSSLRTLERAIGWLKTFRPDV--LVVTGDLVNDQWRHGY 51

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAG-----ISPAKRVFIGEQWQILLLDS 129
           +  AE + S   P   LPGN D    M S L   G       P       +   +  +D 
Sbjct: 52  RLVAENLRSLDCPVHLLPGNGDDVQLMRSELVAVGTWINATGPMHFRTAVDGLTLFGVDV 111

Query: 130 QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTV 189
            V G  +G++    L WL   LAD     +LL +H  PL  G   LDQ   RN   L + 
Sbjct: 112 TVAGQSYGDVLP-HLPWLTSALADVT-TPSLLFMHQPPLRIGIEVLDQVGCRNGSALLST 169

Query: 190 LA-KFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDT--IAPGWRTL 246
           L         +LCGH+H+          +    S C             +   AP +   
Sbjct: 170 LETMHRLPLAILCGHVHRPAFGRLGSMTVQTCGSLCPPNPLLLDGRADLSVIDAPSFLMH 229

Query: 247 ELHADGTLTTEVHRLA 262
           E+ +DG L + V  + 
Sbjct: 230 EV-SDGRLVSHVVSVP 244


>UniRef50_B7QLZ2 Purple acid phosphatase, putative n=2 Tax=Coelomata
           RepID=B7QLZ2_IXOSC
          Length = 316

 Score =  146 bits (370), Expect = 6e-34,   Method: Composition-based stats.
 Identities = 43/283 (15%), Positives = 89/283 (31%), Gaps = 36/283 (12%)

Query: 12  EARVRILQITDTHLFAQKHEALLGVNTWES-----YQAVLEAIRPHQHEFDLIVATGDLA 66
           +     +Q  DT     +       +          +  + A+     +    V  GDL 
Sbjct: 46  KGPFFFIQAADTQFGMIESYIEKKPDPKWDKEIVLTRQAIAAVNRMNPKPSFFVVCGDLI 105

Query: 67  Q--------DQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSAL---QDAGISPAKR 115
                    +     ++     ++S   P V + GNHD                      
Sbjct: 106 DAMPGTDLRNAQEDDFRRVMAEMSS-EVPLVCVCGNHDIGNEPTPESVRSYRDTFGDDYF 164

Query: 116 VFIGEQWQILLLDSQVF--GVPHGELSEFQLEWLERKLADAPER--HTLLLLHHHPLPAG 171
           VF       ++++SQ +       EL + Q  WL+ +L +A       +++  H P    
Sbjct: 165 VFWCGGVMCIVINSQYYENSTHVRELEQEQSSWLDEQLEEAKSGGYKHVVVFQHIPWFLR 224

Query: 172 CSWLDQ----HSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQF 227
               +       L    ++     +   V+ + CGH H+     +    L+ T +   Q 
Sbjct: 225 DPGEENEYFNIVLELRQKMLEKFHR-AGVRAIFCGHYHRNAGGFYKDMELVVTSAVGAQ- 282

Query: 228 KPHCSNFTLDTIAPGWRTLELHADGTLTTEVHRLADTRFQPDT 270
                   L   + G R ++L  D  +  + ++L++     + 
Sbjct: 283 --------LGNDSHGLRIVKLLED-QIQHQYYKLSEIPETVEL 316


>UniRef50_C5SJD5 Metallophosphoesterase n=1 Tax=Asticcacaulis excentricus CB 48
           RepID=C5SJD5_9CAUL
          Length = 257

 Score =  146 bits (370), Expect = 6e-34,   Method: Composition-based stats.
 Identities = 56/267 (20%), Positives = 91/267 (34%), Gaps = 36/267 (13%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +RI  I+D H  A            E+  + L  +       DL+VA+GD+ QD + A +
Sbjct: 1   MRIAHISDLHFGAHDRR------VTETLISTLIELE-----PDLVVASGDITQDATVAEF 49

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRV-------FIGEQWQILLL 127
              +E       P   +PGNHD                   +          +   I  +
Sbjct: 50  VEASEFFKLLPMPAFVIPGNHDLPGLDLRRFIQPWKRYRDHIARELEPELQADLVDIKGI 109

Query: 128 DSQVF-----GVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRN 182
           +S           +G +S  Q   +    A +     +L +HH PL      LD  +L N
Sbjct: 110 NSARMILPSLNWAYGSISARQRHDIADFFAASTTPWRVLTVHHPPLNPPEFPLD-VTLFN 168

Query: 183 AGELDTVLAKFPHVKYLLCGHIHQELDLDW---NGRRLLATPSTCVQFKPHCSNFTLDTI 239
            G+    L +   V  +L GH H              L    ST +          +   
Sbjct: 169 KGKFLETLGE-QKVDIVLSGHQHHAYVETRIMNGHTTLFVCASTAMSV-------RIRKQ 220

Query: 240 APGWRTLELHADGTLTTEVHRLADTRF 266
             G+  L+   D ++  E+ +L+  RF
Sbjct: 221 PQGFNLLDF-KDKSVRIELRQLSGDRF 246


>UniRef50_A6EBB1 Putative uncharacterized protein n=2 Tax=Sphingobacteriales
           RepID=A6EBB1_9SPHI
          Length = 306

 Score =  146 bits (370), Expect = 6e-34,   Method: Composition-based stats.
 Identities = 52/266 (19%), Positives = 90/266 (33%), Gaps = 37/266 (13%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSA--- 72
            +  ITD H+         G    E +++ L  I     + D  +  GD   D S     
Sbjct: 44  TVAHITDVHI-------REGDRAAERFRSCLNHIINKH-KPDFFLNGGDAINDASYDNVV 95

Query: 73  ------AYQHFAEGIASF-RAPCVWLPGNHDF-------QPAMY---SALQDAGISPAKR 115
                  +  + + + +          GNHD           MY     ++   +     
Sbjct: 96  REQVISQWAIWDDCLTTLKGYEVHSCIGNHDTWWKAPTTSDPMYGKDYVVKRLKMPHRYY 155

Query: 116 VFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWL 175
            F  + W   +LD     +    L E Q  WLE +L        +LL+ H+P+      L
Sbjct: 156 SFSRKNWHFFILDGNNANIS---LDEEQYNWLEAELGKLRAGSQVLLMSHYPILGTTQVL 212

Query: 176 DQHSLRNAGELDTVLAKF-PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCS-- 232
                 +  +L  +  K+   V+  L GH H   + ++NG R     +    +       
Sbjct: 213 VGGGHSDCKKLKDLFYKYRDKVRICLSGHNHLSDETEYNGVRYCCNGAMSGFWWGKGDAE 272

Query: 233 ---NFTLDTIAPGWRTLELHADGTLT 255
              +       PG+  L+L+ DGT+ 
Sbjct: 273 SKGDGYYLETPPGYAILDLYDDGTVE 298


>UniRef50_Q2SWK2 Ser/Thr protein phosphatase family protein n=37
           Tax=Burkholderiaceae RepID=Q2SWK2_BURTA
          Length = 306

 Score =  146 bits (370), Expect = 6e-34,   Method: Composition-based stats.
 Identities = 58/249 (23%), Positives = 96/249 (38%), Gaps = 22/249 (8%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQD-QSSAA-- 73
            +Q++D H         +  +   +    +EA+       D ++ TGDL       A   
Sbjct: 44  FVQLSDAHWGFSGPA--INPDARGTLPKAIEAVNALPVAPDFVMFTGDLTHTTDDPAERR 101

Query: 74  --YQHFAEGIASFRA-PCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQ 130
              + F   +A  RA P   +PG HD      +A ++         F  +    +++D+ 
Sbjct: 102 TRMRQFQSIVAQLRAKPLHLMPGEHDASLDAGAAYREI-FGDTHYAFDHKGVHFVVVDNV 160

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
               P G + + Q+EWL + LA  P+   +++  H PL       D  + R+  ++  VL
Sbjct: 161 --SDPAGRVGDAQIEWLAQDLARQPKDARIVVFTHRPLFDLAPQWD-WATRDGAKVVDVL 217

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFK-PHCSNFTL----DTIAP---- 241
             +P+V  +  GHIHQE           A  S       P   +  L    D  AP    
Sbjct: 218 MPYPNVT-VFYGHIHQEHHAMTGHIAHHAARSLMFPLPAPGSQDKRLPVPWDAAAPYRGL 276

Query: 242 GWRTLELHA 250
           GWR + L  
Sbjct: 277 GWREVRLGD 285


>UniRef50_UPI0001745388 Ser/Thr protein phosphatase family protein n=1 Tax=Verrucomicrobium
           spinosum DSM 4136 RepID=UPI0001745388
          Length = 302

 Score =  146 bits (369), Expect = 8e-34,   Method: Composition-based stats.
 Identities = 53/244 (21%), Positives = 82/244 (33%), Gaps = 21/244 (8%)

Query: 18  LQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQ-DQSSAAYQH 76
              +DTH+ A       GV    + ++ +  +         ++ +GD A      A YQ 
Sbjct: 44  ALFSDTHIDADPLAVSRGVTMAANLRSCVAEVLARAERPAGLILSGDCAHLKGMRADYQT 103

Query: 77  FAEGIASF---RAPCVWLPGNHDFQPAMYSALQDAGISPAKRVF----IGEQWQILLLDS 129
               +      + P   L GNHD + A+   L  A        F            LLDS
Sbjct: 104 LKPLLQPLVAAKLPVHLLMGNHDDRVAVTEVLDCATSPAVPSRFVSVQETPHANWFLLDS 163

Query: 130 Q-VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDT 188
                   G L   QL WL R+L    +R  ++++HH+            +L ++  L  
Sbjct: 164 LDKVNSTPGVLGGEQLAWLGRELDARSDRPAVIVVHHN---ITLQESKTDALLDSTSLLE 220

Query: 189 VLAKFPHVKYLLCGHIHQELDLDWN-GRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLE 247
           +L     VK  + GH H+    +   G   +  P     FK             GW    
Sbjct: 221 LLRPRRQVKACIYGHTHRWSHTEDESGLHFINLPPVAYVFKQ--------EFPNGWVLAT 272

Query: 248 LHAD 251
           L  D
Sbjct: 273 LQPD 276


>UniRef50_Q9YDE7 Putative uncharacterized protein n=1 Tax=Aeropyrum pernix
           RepID=Q9YDE7_AERPE
          Length = 724

 Score =  146 bits (368), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 51/275 (18%), Positives = 99/275 (36%), Gaps = 43/275 (15%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPH--QHEFDLIVATGDLAQ 67
                + I+ +TD H  A     L  V     +   +  +     +   DL+V TGD++ 
Sbjct: 162 TPPDELVIMHLTDIHFGAIDKGILNDV----KFARDVALVNTLKYELGLDLVVVTGDISD 217

Query: 68  DQ-SSAAYQHFAEGIASFRAPCVWLPGNHDFQPA------MYSALQDAGISPAKRVFIGE 120
              + ++Y+++A  +     P + +PGNHD+         +        +          
Sbjct: 218 IGINVSSYRNWAFAMNQLLVPTMTVPGNHDWAQVPGLESFLLDFYGKYNVPARYWAAKWG 277

Query: 121 QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHT--LLLLHHHPLPAGCSW-LDQ 177
            +  + LDSQ      G +    L++LE  L+         ++L+HH        +  D 
Sbjct: 278 NFLFIGLDSQ----SEGYVEPEGLDFLENVLSQYSGEDVVAIILVHHPIFSDPGRYKGDP 333

Query: 178 HSLRNA------------GELDTVLAKFPHVKYLLCGHIHQELDLDW---NGRR-LLATP 221
            S R A                 ++ ++  VK +  GHIH++ D  +   +       T 
Sbjct: 334 ESFRGALYGSWESKFELVERFFDIINRYDMVKVVFSGHIHRDADAIYFRQDNTPVYFITT 393

Query: 222 STCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTT 256
           +T +   P    +       G + + + ADG +  
Sbjct: 394 TTAMHGHPQGYFW-------GAKVVRVTADGQVEV 421


>UniRef50_D2EY57 Putative uncharacterized protein n=1 Tax=Bacteroides sp. D20
           RepID=D2EY57_9BACE
          Length = 621

 Score =  146 bits (368), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 51/292 (17%), Positives = 101/292 (34%), Gaps = 40/292 (13%)

Query: 3   SLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVAT 62
           S L+   +         ++D HL +            +  +  +E I       D  + +
Sbjct: 4   SALSYGQSNRVSFTFAWLSDVHLNS-------FAYAEDDLRQSIEDINA-NPAVDFTILS 55

Query: 63  GDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYS-ALQDAGISPAKRVFIGEQ 121
           GD+ +   +  +    E +  FR P + LPGNHD   +     + +     +   +  + 
Sbjct: 56  GDVTEFGDTKEFLLLQEILEGFRKPYLLLPGNHDVNWSENGCTMFNKIFQASHFCYDWQG 115

Query: 122 WQILLLD---SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQH 178
            + +      S   G PH  +   ++ WL+  +   P+   ++ ++H PL          
Sbjct: 116 VRFIGCGTGPSLRMGPPH--IPREEILWLDSIVRATPKELPVIFVNHFPL--------NR 165

Query: 179 SLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKP--------- 229
            L N  E+  +L K  +V   L GH+H     D  G   +   S+  +  P         
Sbjct: 166 DLSNWYEVTDIL-KTRNVLVTLAGHLHTNRAYDAEGIPAVIGRSSLRREDPIGGYNLVTV 224

Query: 230 ------HCSNFTLDTIAPGWRTLELHADGTLTTEV--HRLADTRFQPDTASE 273
                  C         P W  + L+A    ++ +   +     ++PD +  
Sbjct: 225 NEDSITFCERIIQTETRPAWNIVRLNATAIASSNIPGEKKDTVYYRPDFSIN 276


>UniRef50_A6WZI2 Metallophosphoesterase n=49 Tax=Proteobacteria RepID=A6WZI2_OCHA4
          Length = 281

 Score =  146 bits (368), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 60/271 (22%), Positives = 97/271 (35%), Gaps = 29/271 (10%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           +RI+QITDTHL   K         WE   A ++       + DL++ TGDL  D +    
Sbjct: 1   MRIVQITDTHLSPIKPHFNRN---WEPLVAWIDQ-----QKPDLVIHTGDLTVDGADVEA 52

Query: 75  QHF--AEGIASFRAPCVWLPGNHDF---------QPAMYSALQDAGISPAKRVFIGEQWQ 123
                   +    A  + LPGNHD                      I P +       W+
Sbjct: 53  DLLFCRTCLNELPARVLSLPGNHDIGHLPESHQPVNPQRLMRWRRHIGPDRWAENFGNWR 112

Query: 124 ILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQ----HS 179
           I+ L+S V G    E    Q +WLE +L ++  +   +  H           D       
Sbjct: 113 IIGLNSLVIGSGEAE-EAEQFQWLEDELKNSDGKPVAVFAHKPLFVDDPDEGDSGYWGIR 171

Query: 180 LRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTI 239
                 L  + A++ +V+    GH+H+    D  G   +  P+      P   +   + I
Sbjct: 172 PAPRQRLYDLFAQY-NVQLHASGHLHRAWSGDAFGTNYVWAPAAAFIVGPMERDLPGERI 230

Query: 240 APGWRTLELHADGTLTTEVHRLAD-TRFQPD 269
             G    +L      T+ + R+ + T +  D
Sbjct: 231 L-GAAIHDLDE--VATSSIVRIDELTPYVID 258


>UniRef50_B9TAV3 Putative uncharacterized protein n=1 Tax=Ricinus communis
           RepID=B9TAV3_RICCO
          Length = 279

 Score =  145 bits (367), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 51/251 (20%), Positives = 86/251 (34%), Gaps = 17/251 (6%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAY 74
           + I QI+D H            ++       +  +   Q +  L+V +GDL        Y
Sbjct: 37  MLIAQISDIHASPTN-------DSMARLDRAVSWLAVLQPD--LLVVSGDLVDGNWLEGY 87

Query: 75  QHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIG----EQWQILLLDSQ 130
              +  +       + LPGN D +  M + +        +             I+ +D+ 
Sbjct: 88  GLISTSLHRLACRSLILPGNSDDRAVMRTIMPQPDYWHDRPAMHFIEPCGGSVIIGVDTC 147

Query: 131 VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVL 190
           V G  +G+++   L WL R LA +P    LL  HHH  P G   LD    +    L  +L
Sbjct: 148 VDGEAYGDVT-QHLSWLRRALAGSPNGTALLFTHHHVFPCGIPPLDAVMCKGTQALAGLL 206

Query: 191 AKFPH-VKYLLCGHIHQELDLDWNGRRLLATPSTC--VQFKPHCSNFTLDTIAPGWRTLE 247
                    +  GH+H+ +   + G       S C         S        P     +
Sbjct: 207 KSGIRPPAAICSGHVHRSMSSLFAGIPAYTCGSICPANPLMLDASRVPQAADPPALMIHD 266

Query: 248 LHADGTLTTEV 258
           L     +++ V
Sbjct: 267 LRHGHLVSSHV 277


>UniRef50_C6XUF6 Metallophosphoesterase n=1 Tax=Pedobacter heparinus DSM 2366
           RepID=C6XUF6_PEDHD
          Length = 611

 Score =  144 bits (365), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 45/247 (18%), Positives = 89/247 (36%), Gaps = 30/247 (12%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
           +     +   +TDTH+     E        E  +  +  I     + D IV TGD+ +  
Sbjct: 17  SNAQTFKYAFVTDTHVGTATGE--------EDLRRTVNDINKQT-DLDFIVVTGDVTEMG 67

Query: 70  SSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQD-AGISPAKRVFIGEQWQILLLD 128
           +    +     ++  + P   +PGNHD   +    +         K  F    ++ +   
Sbjct: 68  TKLELKLAKSILSELKKPYYVIPGNHDTGWSESGGVDFIREFGDDKFTFDHNGYRFIACA 127

Query: 129 SQVFGV-PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELD 187
           S  +     G +    + WL++ L +      ++ ++H+P+         +SL N  E  
Sbjct: 128 SGPYVRMSDGHIPRDAVIWLDKVLKNTSATMPVIFINHYPV--------DNSLDNWYEAT 179

Query: 188 TVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLE 247
             + K+ +++Y +CGH H    L++ G       S          N        G+  + 
Sbjct: 180 DRIKKY-NIQYAICGHGHSNQALNFEGVPGTMGRS----------NLRAKDSLGGYNIVT 228

Query: 248 LHADGTL 254
           +  D  L
Sbjct: 229 MRKDSVL 235


>UniRef50_Q3Y3L7 Metallophosphoesterase n=1 Tax=Enterococcus faecium DO
           RepID=Q3Y3L7_ENTFC
          Length = 267

 Score =  144 bits (365), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 57/263 (21%), Positives = 101/263 (38%), Gaps = 16/263 (6%)

Query: 15  VRILQITDTHLFAQKHEALLGVN---TWESYQAVLEAIRPHQ--HEFDLIVATGDLAQDQ 69
           +R L ++D H        L       T ++ Q  LE +        +D I+ TGDL  + 
Sbjct: 1   MRFLHLSDIHFRENYQTNLFTAELFPTIKNPQLALEKLLQELSLTVYDFILLTGDLVHEG 60

Query: 70  SSAAYQHFAEGIASF--RAPCVWLPGNHDFQPAMYSALQDAGISPAKRVF--IGEQWQIL 125
             + YQ   + +  +    P  +  GNHD +   +  +        + +        +I+
Sbjct: 61  GISDYQVLRKMLDQYFPTTPYYFCRGNHDRRSVFFEGMSVESNETGEYIHCTNQNGLRII 120

Query: 126 LLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGE 185
            LDS       G++S  Q+  L+  L    E+ T+LL+HH       SW D   +    E
Sbjct: 121 SLDSAQDTQHEGKISIGQMIQLQEWLGTPAEKGTILLVHHPL-----SWEDPSIVTEVPE 175

Query: 186 LDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRT 245
               L     +  +  GHIHQ    ++  ++     S       +  +++L T   G+ +
Sbjct: 176 GFAELIAESDILGIFVGHIHQGSSAEFADKKQFMAESLSFGVDEY-PDYSLFTNRTGFTS 234

Query: 246 LELHADGTLTTEVHRLADTRFQP 268
             L  DG + T  H L   + + 
Sbjct: 235 GSL-IDGKIFTYQHYLTPHQIEI 256


>UniRef50_C6A3A3 Metallophosphoesterase, calcineurin superfamily n=1
           Tax=Thermococcus sibiricus MM 739 RepID=C6A3A3_THESM
          Length = 576

 Score =  144 bits (365), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 36/213 (16%), Positives = 77/213 (36%), Gaps = 15/213 (7%)

Query: 52  HQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGIS 111
           +  E   I+ +GDL        +    +   +F  P   +PGNH+++    +        
Sbjct: 377 NHDEGAFIINSGDLVYSGKVEEWAELLKEW-TFNKPVFVVPGNHEYRGEGKNIYHK-FFG 434

Query: 112 PAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAP--ERHTLLLLHHHPLP 169
           P    F+  ++  +  ++         L+  Q  WLE +L  A    +  ++ +H  P+ 
Sbjct: 435 PTDYSFVLGKYYFIFTNNVENDY---RLTSSQWAWLESELEKAKRLGKIPIISMHAPPID 491

Query: 170 AGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKP 229
                       +A +L  ++  +    + L GHIH     + +G  ++ T         
Sbjct: 492 PRPEGDHAMDTNHAKKLLELMKAYD--AFGLFGHIHIYWYGEKDGVEMVITGGGGAPLYA 549

Query: 230 HCSNFTLDTIAPGWRTLELHADGTLTTEVHRLA 262
                        +  ++++A  +LT E  R+ 
Sbjct: 550 KPDEGGF------YHYVKINAYDSLTVEPIRVD 576


>UniRef50_UPI00019737CF serine/threonine protein phosphatase family protein n=1
           Tax=Clostridium sp. M62/1 RepID=UPI00019737CF
          Length = 496

 Score =  144 bits (364), Expect = 3e-33,   Method: Composition-based stats.
 Identities = 53/306 (17%), Positives = 111/306 (36%), Gaps = 62/306 (20%)

Query: 9   LAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQD 68
           LAG+     +Q+T     +     L G    +++   ++     +   DL+V +GDL  +
Sbjct: 105 LAGKRCQSFVQMT---YGSDGRVLLYGWEVMDAFVEDMK-----EKRPDLVVLSGDLTLN 156

Query: 69  QSSAAYQHFAEGIASFR---APCVWLPGNHDFQPAMYSALQDAG-----------ISPAK 114
              A+++  A  +        P + +PGNHD                         +   
Sbjct: 157 GERASHEELASILRELDEEDIPVLVVPGNHDINNPNARRFSGTQSYLVESVSPEEFADIY 216

Query: 115 RVF------------------IGEQWQILLLDSQVFGVPH---GELSEFQLEWLERKLAD 153
             F                  + +   +L+LDS  +   +   G +      W+E  L +
Sbjct: 217 ADFGYVAADSRDPSSLSYLYKVDDSLWLLMLDSCQYDPANLTGGMIQSGTYRWMEPILYE 276

Query: 154 AP--ERHTLLLLHHHPLP---AGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQEL 208
           A   +   + + HH+ L       ++ D  ++ +  EL  +L+    V+  L GH+H + 
Sbjct: 277 AWENDTEVITVTHHNLLEQSGVSDAFYDDCTIEHNEELLQMLSDNE-VRLHLSGHLHLQH 335

Query: 209 DLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTEVHRLADTRFQP 268
            ++ +G   + T S             L     G+  +EL+ DG++T     +   ++  
Sbjct: 336 YMEEDGVTEVVTGS-------------LVMAPCGYGVVELYEDGSITYHTQPVNVEKWAR 382

Query: 269 DTASEG 274
           + + + 
Sbjct: 383 ENSYKN 388


>UniRef50_A4WK20 Metallophosphoesterase n=5 Tax=Thermoproteaceae RepID=A4WK20_PYRAR
          Length = 641

 Score =  144 bits (364), Expect = 3e-33,   Method: Composition-based stats.
 Identities = 54/275 (19%), Positives = 100/275 (36%), Gaps = 53/275 (19%)

Query: 13  ARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQ-DQSS 71
             +RI+Q+TD H+  +       ++    Y+ +  A+      +D++  TGDLA      
Sbjct: 108 GPLRIIQLTDIHVGVE-------LDMASLYRLIHGALVASGGPYDVVFFTGDLADVGGQV 160

Query: 72  AAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQV 131
             Y  F +  A+   P   +PGNHD             +       +   + I+ LDS  
Sbjct: 161 WHYTLFTKYAATIPKPVFAIPGNHDHAGDDPLTNYQKFVGRPVWYRVIGPYLIIGLDSGF 220

Query: 132 FGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPA----------GCSWLDQHS-- 179
                G L + Q++  E  L   P++  ++L+HH P             G   +D+ +  
Sbjct: 221 ----DGYLRDDQVKMYEEVLKRYPDKVKIVLIHHPPFYLQDSYVVETYRGPQDVDRLNKD 276

Query: 180 --------------LRNAGELDTVLA---KFPHVKYLLCGHIHQ-ELDLDWNGRRLLATP 221
                         L+N    +  L    ++  V  ++ GH+H     +  NG   + T 
Sbjct: 277 PTGRRSYYIVYTSYLQNRPAFEKFLDLTIRYK-VALVMAGHVHSGNSTIVINGTYFVTTR 335

Query: 222 STCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTT 256
           +                 + G+RT  ++ DG +  
Sbjct: 336 TLGGSI----------DTSHGFRTYVVYPDGRVEV 360


>UniRef50_UPI0001BC808F hypothetical protein BacD2_17610 n=1 Tax=Bacteroides sp. D2
           RepID=UPI0001BC808F
          Length = 520

 Score =  143 bits (361), Expect = 7e-33,   Method: Composition-based stats.
 Identities = 51/272 (18%), Positives = 97/272 (35%), Gaps = 38/272 (13%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQD--QSSAAY 74
           I   TD HL   + +  L       Y  ++  I+   ++    +  GD+  D       Y
Sbjct: 115 IFMFTDIHLTNDRVDNDLPQFGKTFYPDIVSQIKARANKPVYAICLGDMTTDVKWHINHY 174

Query: 75  Q--HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGI----------SPAKRVFIGEQW 122
               + E +  F  P     GNHD +  +   + D              P    F    W
Sbjct: 175 ALPEYLETMKDFPIPVYHAMGNHDNERKVIENISDWDFYGESVYKDVIGPNYYSFNIGAW 234

Query: 123 QILLLDSQVFGVP---HG--------ELSEFQLEWLERKLADAPERHTLLLLHHHPLPAG 171
            +++LD+ + G P   +G         + + Q+EW+++ L+  P+   +++  H P P  
Sbjct: 235 HVMILDNIITGGPVKKNGKLNYQFTYRIDDQQMEWIKKDLSFMPKNTPIMVGMHVP-PLK 293

Query: 172 CSWLD------QHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDW-NGRRLLATPSTC 224
            + +        +   NA E     A+F  V+ +  GH H+  +  + +   L   PS  
Sbjct: 294 YTGMKNGVLETDYDFENAKEFLDCFAEFNQVQ-IFAGHTHRSSNYVYGDNITLHNLPSAS 352

Query: 225 VQFKPHCSNFTL----DTIAPGWRTLELHADG 252
                     +     D    G+  +++  D 
Sbjct: 353 AVSWKINGETSRLISEDGSPAGYWIIKVKGDN 384


>UniRef50_A6WWL5 Metallophosphoesterase n=1 Tax=Ochrobactrum anthropi ATCC 49188
           RepID=A6WWL5_OCHA4
          Length = 271

 Score =  143 bits (360), Expect = 7e-33,   Method: Composition-based stats.
 Identities = 57/259 (22%), Positives = 84/259 (32%), Gaps = 23/259 (8%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQS--SA 72
           VR++QI+DTHL   K      V  W   +  L           LI+ +GD++ D +    
Sbjct: 2   VRVIQISDTHLGRHKAHF---VENWRPLKNWLA-----SENPKLIIHSGDISVDGADVED 53

Query: 73  AYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQD---------AGISPAKRVFIGEQWQ 123
            +    E +    AP + +PGNHD      +                           W+
Sbjct: 54  DFAFCREVMVDLPAPMLVVPGNHDVGEPQSAHQPANEHRLERWNRQYGADFWAKDVGNWR 113

Query: 124 ILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNA 183
           +L  DS +         E Q  WLER++  A  R      H      G   +D       
Sbjct: 114 LLGFDSMILSSGLAA-EEAQFHWLERQMESADGRRIAWFTHQPLFINGWEDIDNGYWSVK 172

Query: 184 GE---LDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA 240
            E       L +   V  +  GH+H   D   +G + +  PS      PH          
Sbjct: 173 REPRTRLQRLTQRFGVDLIASGHLHLSHDFILDGVQFVWCPSAAFAVGPHMQPPLGGEKQ 232

Query: 241 PGWRTLELHADGTLTTEVH 259
            G    +    G   T VH
Sbjct: 233 LGAVRYDFSETGFSFTRVH 251


>UniRef50_A1HNK3 Metallophosphoesterase n=1 Tax=Thermosinus carboxydivorans Nor1
           RepID=A1HNK3_9FIRM
          Length = 345

 Score =  143 bits (360), Expect = 8e-33,   Method: Composition-based stats.
 Identities = 51/227 (22%), Positives = 84/227 (37%), Gaps = 17/227 (7%)

Query: 26  FAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFR 85
           FA   +   G + + S    L+ I   +   +  V  GDL     +  Y+ F    A   
Sbjct: 126 FAVFGDNRDGRDVYLSL---LDKINALRP--EFAVNGGDLVPAGRAGEYEQFLADSARLT 180

Query: 86  APCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLE 145
            P     GNHD Q      L +  ++P    F+      L+LD+       G++   QL 
Sbjct: 181 IPYYTALGNHDIQGDGR-TLYNRLLAPNYYDFVWGNSLFLVLDNA-----DGDMDARQLA 234

Query: 146 WLERKLADAPERHTLLLLHHHPL-PAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHI 204
           WLE KL +   RHT +++H  P  P        +S   A  L  + A++  V  + C HI
Sbjct: 235 WLENKLKERTARHTFIIMHKPPFDPRPGRSHTVNSRELADRLQNLAAQY-GVTAVFCSHI 293

Query: 205 HQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHAD 251
           H     +  G     T           +   +      +  ++++ D
Sbjct: 294 HMYYQGERLGVPYYITGGAGAPLYAARAAGGV----YHFVLVKVNGD 336


>UniRef50_B4WC05 Ser/Thr protein phosphatase family protein n=1 Tax=Brevundimonas
           sp. BAL3 RepID=B4WC05_9CAUL
          Length = 321

 Score =  143 bits (360), Expect = 9e-33,   Method: Composition-based stats.
 Identities = 51/285 (17%), Positives = 87/285 (30%), Gaps = 49/285 (17%)

Query: 15  VRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ----- 69
            + + ++DTH+  +           E        +     + D +V  GD   D      
Sbjct: 47  FKFVFLSDTHIQPEDG-------AVEGVHRCFAQVAAS--DADFVVHGGDHVFDAMEVGR 97

Query: 70  --SSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYS------------ALQDAGISPAKR 115
             + A    + +       P   + GNHD                           P   
Sbjct: 98  ARADAQMALYRQSERLLDKPVRHVLGNHDCFGLFEKSGVDPSEPGYGKRYFIDQFGPTYY 157

Query: 116 VFIGEQWQILLLDSQVFG--VPHGELSEFQLEWLERKLADAPERHTLLLLHHHPL----- 168
            F  +  + L+LDS  F      G +   QL WL  + A       +++L H PL     
Sbjct: 158 GFSHKGVRFLVLDSIGFKGRNYEGRIDAEQLAWLRGEFAILSPSDPVVVLTHIPLVTALE 217

Query: 169 -PAGCSW----LDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPST 223
                 W     D   + N  E+  +     +V  +L GH H    ++  G R +++ + 
Sbjct: 218 CYEPEDWAASPYDWTRVMNGREVMRLFQNH-NVLGVLQGHGHVHETVEVAGVRYISSGAV 276

Query: 224 CVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTEVHRLADTRFQP 268
                             G+  + + A+G L T   R     F P
Sbjct: 277 AGADWRGS----FLGTPEGYLEVTI-ANGRLDT---RFRTYGFTP 313


>UniRef50_A6DB66 Putative uncharacterized protein n=1 Tax=Caminibacter
           mediatlanticus TB-2 RepID=A6DB66_9PROT
          Length = 1054

 Score =  143 bits (360), Expect = 9e-33,   Method: Composition-based stats.
 Identities = 43/266 (16%), Positives = 89/266 (33%), Gaps = 44/266 (16%)

Query: 17  ILQITDTHLFAQKHEAL---LGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQ------ 67
            + + D HL A           +    + +  ++ I       +L++ TGD+        
Sbjct: 222 FIHMADVHLTADNEVEDVFGGKIPPVTTVKEDIKEINSFNP--NLVIQTGDIVALADQYP 279

Query: 68  -DQSSAAYQHFAE-GIASFR---APCVWLPGNHD-----------FQPAMYSALQDAGI- 110
            D+    Y+   E  +   +    P ++ PGNHD             P  Y+ L    I 
Sbjct: 280 LDKDEEWYKLAKENIVDPIKNKEIPFLFAPGNHDPAGYKLKDVNKSDPRYYNGLIFKYIL 339

Query: 111 ---SPAKRVFIGEQWQILLLD---SQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLH 164
                    +  + +  ++LD   ++  G     L + QLEWL+ +L    ++  ++  H
Sbjct: 340 TNIDKTYYSYDYDNYHFIILDPKETEESGYRTVILPQEQLEWLKNELNANSDKFFIIAYH 399

Query: 165 HHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTC 224
                 G    D +      +   ++  +     L+ GH H    +  +G       + C
Sbjct: 400 QPL---GSWDKDSY-----QKFINLILPYKLRTLLIVGHTHDNRLIYRDGIPEYQGGAVC 451

Query: 225 VQFKPHCSNFTLDTIAPGWRTLELHA 250
             +     +   D    G+   ++  
Sbjct: 452 GDWWNTGKDP--DGSPMGYAVYKIDK 475


>UniRef50_C1ZIM9 Predicted phosphohydrolase n=1 Tax=Planctomyces limnophilus DSM
           3776 RepID=C1ZIM9_PLALI
          Length = 322

 Score =  143 bits (360), Expect = 9e-33,   Method: Composition-based stats.
 Identities = 48/241 (19%), Positives = 80/241 (33%), Gaps = 29/241 (12%)

Query: 1   MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV 60
           + +L+T      A +R   ITD H         +  +  E  +A +EA+       D I 
Sbjct: 19  LPALVTQAQEQTAPLRFGVITDLH-------QDIIPDAPERLRAFVEAM--TLANVDFIC 69

Query: 61  ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGIS--PAKRVFI 118
             GD       A  Q   +   SF  P   + GNHD        +             F 
Sbjct: 70  QLGDFC-IPKPAN-QPLMKIWNSFPGPKYHVLGNHDMDAGYKPQVTAEFYGMPARYYAFS 127

Query: 119 GEQWQILLLDSQVFGV----PHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSW 174
            +  + ++LD    G         +   Q+ WL+ +L  + E   +++L H PL      
Sbjct: 128 AKGVRFIVLDGNEPGGQKSGYARYIGPDQIAWLKTELEKSNE--PVIVLIHQPLETDS-- 183

Query: 175 LDQHSLRNAGELDTVLAKF----PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPH 230
                + N   +  +L         V  +  GH+HQ+     NG   +   S    +   
Sbjct: 184 ----GIENHAAIQKILEGTLSNKSPVVAVFAGHLHQDYVRPVNGIPYIQINSAAYHWMGD 239

Query: 231 C 231
            
Sbjct: 240 Q 240


>UniRef50_C6X3M3 Phosphoribosylglycinamide formyltransferase n=3 Tax=Bacteria
           RepID=C6X3M3_FLAB3
          Length = 425

 Score =  143 bits (360), Expect = 9e-33,   Method: Composition-based stats.
 Identities = 50/253 (19%), Positives = 97/253 (38%), Gaps = 23/253 (9%)

Query: 17  ILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQH 76
           I  ITD HL  +K+ +  GV+   +++ VL+ ++        I+  GDL       A + 
Sbjct: 195 IAFITDLHL-HEKNVSKKGVDAVANWKTVLQDVKARGISR--IILGGDL---GEKEALKI 248

Query: 77  FAEGIASFRAPCVWLPGNHDFQPAMYSALQD-AGISPAKRVFIGEQWQILLLDSQVFGVP 135
             + I  F      + GNHD      +   +  G               + LD+  +   
Sbjct: 249 IFDDIKDFD--FRLILGNHDKISDFRTFFAETVGKQELYYSAQISGNDCIFLDTSSY--- 303

Query: 136 HGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPH 195
             +LS+ Q  +L+  L        ++ +HH  L  G     +H L+N  +++ +L +   
Sbjct: 304 --KLSQEQRSYLKNWLGSTEN--PVVFIHHPVLDDGSWMDKEHPLKNKTQVEEILRQSGK 359

Query: 196 VKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLT 255
              L+ GH H    +  +  R + +P+   Q   +  ++  DT + G+  L        +
Sbjct: 360 NVTLISGHYHHFYKVTSDKIRQVISPAVSYQI-LNSKSYQADTKSFGYLIL------GFS 412

Query: 256 TEVHRLADTRFQP 268
            +   +    F  
Sbjct: 413 EQEVSIEAVNFSV 425


>UniRef50_B9XC60 Metallophosphoesterase n=1 Tax=bacterium Ellin514
           RepID=B9XC60_9BACT
          Length = 303

 Score =  142 bits (359), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 53/232 (22%), Positives = 92/232 (39%), Gaps = 15/232 (6%)

Query: 18  LQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLA-QDQSSAAYQH 76
             ++D HL A + +   G+N  +++  V   +   +     ++ +GDLA     SA Y  
Sbjct: 43  ALVSDIHLAADRKKLGRGINMADNFTQVTTQLLDPKWRHSAMLISGDLAFNSGESADYAT 102

Query: 77  FAEGIASF---RAPCVWLPGNHDFQPAMYSALQDAGISPAK------RVFIGEQWQILLL 127
             E +        P     GNHD +   + A+ +A  +          +    +    +L
Sbjct: 103 VTELLQPVQAGGIPIHLTLGNHDNREHFWDAIAEAKAAKRPVTDHQVSLLRSSRANWFVL 162

Query: 128 DS-QVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGEL 186
           DS +      G + E QL+WL   L D   +  L+++HH+      +      L++  +L
Sbjct: 163 DSLEQTLATPGLIGEAQLDWLAHALDDNKRKPALIVVHHNL---NDNSGKPSGLKDGDKL 219

Query: 187 DTVLAKFPHVKYLLCGHIHQELDLD-WNGRRLLATPSTCVQFKPHCSNFTLD 237
             ++    HVK LL GH H        +G  L+  P T   FK    N  + 
Sbjct: 220 LDIIRPRKHVKALLYGHSHDWEVKQDSSGIHLINLPPTAYVFKEGKPNGWVH 271


>UniRef50_C5EF84 Serine/threonine protein phosphatase family protein n=2
           Tax=Clostridiales RepID=C5EF84_9FIRM
          Length = 475

 Score =  141 bits (357), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 60/319 (18%), Positives = 111/319 (34%), Gaps = 71/319 (22%)

Query: 8   PLAGEARVRILQITDTHLFAQK--------------HEALLGVNTWESYQAVLEAIRPHQ 53
           PL G    RI+ +TD H  A+                +  L    WE   A  E I+   
Sbjct: 63  PLKGGK--RIVVMTDIHYLAESLTDEGDMFQSMVEHGDGKLTNYVWEITDAAFEEIQLLN 120

Query: 54  HEFDLIVATGDLAQDQSSAAYQHFA---EGIASFRAPCVWLPGNHDFQPA------MYSA 104
            +   ++ +GDL+      +++  A   + +       V +PGNHD              
Sbjct: 121 PDV--LIISGDLSLQGEKKSHEELAGKLDALERAGITVVVIPGNHDINNPSAAVYSGADR 178

Query: 105 LQDAGISPAKRVFIGEQW-----------------------QILLLDSQVF---GVPHGE 138
                 +PA  V I +++                       ++L+LD+  +       G 
Sbjct: 179 YPAEPTTPADFVRIYKEFGYSEANSRDTSSLSYTYDLSPSMRLLMLDTCQYEPRNRVGGM 238

Query: 139 LSEFQLEWLERKLADAPERHTLL--LLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHV 196
           +     EW++R+L  A E   +L  + HH+ L     ++D  ++ ++ EL   L    ++
Sbjct: 239 IKTETYEWIDRQLEAANEDGVILLPVAHHNLLEESKVYVDDCTIEHSEELIQKLEG-ENI 297

Query: 197 KYLLCGHIHQELDLDWN--GRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTL 254
              L GH+H +  +  N  G   + T S               T    +  LE   D + 
Sbjct: 298 PLFLSGHLHVQHFMRNNSFGIHEIVTSSLS-------------TPPCQYGVLEYMEDESF 344

Query: 255 TTEVHRLADTRFQPDTASE 273
           +    ++   ++     S 
Sbjct: 345 SYHTRQVDMEKWARRHRST 363


>UniRef50_D1B7Z2 Metallophosphoesterase n=1 Tax=Thermanaerovibrio acidaminovorans
           DSM 6589 RepID=D1B7Z2_THEAS
          Length = 278

 Score =  141 bits (357), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 54/259 (20%), Positives = 94/259 (36%), Gaps = 28/259 (10%)

Query: 1   MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV 60
           ++S+L+ P+ GE  +R L + DT                  ++ ++  +R  Q     ++
Sbjct: 40  LDSILSTPVEGE--LRFLVVGDT------------RGPGSRFRFLVPQMREDQ--GLFVI 83

Query: 61  ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE 120
             GDL    +   Y+   E + S R P + + GNH+         +D   S   R F+  
Sbjct: 84  HLGDLTNRGTQGEYREALELLRSIRKPFLVVIGNHELVDRGRGRFEDIFGSWRDRAFVLG 143

Query: 121 QWQILLLDSQVFGVPHGE-LSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHS 179
              ++LLD+       G  LSE +L WL+R+LA  P    ++ +H               
Sbjct: 144 GALLVLLDNA-----DGRPLSEERLRWLDRELASHPG-PKMVFMHQPLFDPRPGKSHAMD 197

Query: 180 LRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTI 239
            R A E+  VL +   V  +   H+H     DW+G     +                   
Sbjct: 198 ERGAREMLEVLKRH-RVDRVFASHVHAFFQGDWDGVPYTISGGGGASLYSRDPESGFHH- 255

Query: 240 APGWRTLELHADGTLTTEV 258
              +  + +   G     V
Sbjct: 256 ---YHRVTVGPGGVRVETV 271


>UniRef50_C7PSE2 Putative uncharacterized protein n=1 Tax=Chitinophaga pinensis DSM
           2588 RepID=C7PSE2_CHIPD
          Length = 496

 Score =  141 bits (357), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 46/258 (17%), Positives = 87/258 (33%), Gaps = 27/258 (10%)

Query: 11  GEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLI--VATGDLAQD 68
            + +   +   D  + ++K   LL   +    QA+++       +  LI  +  GDL  D
Sbjct: 128 DDRKHAFVVWADPQMKSKKDVELLMSQSVPDLQALVK----SYPKDLLIHGIGCGDLVWD 183

Query: 69  QSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYS-----ALQDAGISPAKRVFIGEQWQ 123
                +  + E +     P   + GNHD      +             P    +      
Sbjct: 184 -EFELFADYKEAVGKTGIPFFNVIGNHDMDNEARTDDGSSNTFKKQFGPTYYSYNRGDIH 242

Query: 124 ILLLDSQVFGVPH----GELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHS 179
            ++LD   F        G ++E QL+WL++ LA      T++L  H P   G    +   
Sbjct: 243 YIVLDDVFFLGAAKNYIGYITENQLQWLDQDLAHVKPGSTIVLSTHIPTFTGQQRRNGKP 302

Query: 180 -------LRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCS 232
                  + N  +L  +LA +    +++ GH H   + +          + C  +     
Sbjct: 303 EEVGGGTVANRKQLYKMLAPYK--VHIMSGHTHFNDNWEEGDIMEHNHGTVCGAWWTGP- 359

Query: 233 NFTLDTIAPGWRTLELHA 250
               D    G+   E+  
Sbjct: 360 -ICGDGTPSGYGVYEVDG 376


>UniRef50_Q2NGW0 Predicted phosphohydrolase n=2 Tax=Methanobacteriaceae
           RepID=Q2NGW0_METST
          Length = 243

 Score =  141 bits (356), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 48/239 (20%), Positives = 95/239 (39%), Gaps = 24/239 (10%)

Query: 16  RILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQ 75
           +I+ I+D H               +     ++ I   Q     +V +GDL        + 
Sbjct: 3   KIVHISDLH-------TGYAQFREDLLLQTIDEINKIQP--SAVVISGDLTDQGFYREFI 53

Query: 76  HFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQ--WQILLLDSQVFG 133
              E I   +   + +PGNHD +    +  ++        V   ++   +I+ LDS    
Sbjct: 54  EAKEYIDLIQPKTLIVPGNHDARNIGDTVFEEL-FGKRYSVLELKEEAIKIIGLDSSEPD 112

Query: 134 VPHGELSEFQLEWLERKLADAPERHTL--LLLHHHPLPAGCSWLDQHSLRNAGE-LDTVL 190
           + HG++   Q +++E ++ADA E+     ++LHHH +    +  +++ L +AG+ L T+L
Sbjct: 113 LGHGKIGRLQKKFMEDEIADAKEKGLFIIIVLHHHIISIPNTGRERNILSDAGDILLTIL 172

Query: 191 AKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELH 249
               +V  +L GH H       N        +         S        P +  ++++
Sbjct: 173 E--NNVNLVLSGHKHVPHAWKMNNTLFATAGTVS-------SMKLRGNTCPSYNVIDIN 222


>UniRef50_UPI000186DB0B conserved hypothetical protein n=1 Tax=Pediculus humanus corporis
           RepID=UPI000186DB0B
          Length = 503

 Score =  141 bits (356), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 48/248 (19%), Positives = 87/248 (35%), Gaps = 21/248 (8%)

Query: 12  EARVRILQITDTHLFA-----QKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLA 66
           +     +Q  DT           ++ +      E  + V++ +   + +    V  GDL 
Sbjct: 25  KEPFYFIQGADTQFGFIARELDNNKIVTWEKEIELTENVIKRVNKMRPKPKFFVMCGDLC 84

Query: 67  QDQSSAAY-------QHFAEGIASFR--APCVWLPGNHDFQPAMYSA---LQDAGISPAK 114
            +  +  +         F +         P V + GNHD   +       L ++      
Sbjct: 85  DEMPNNDFLLRKKQESDFKKVFQKLDKDIPLVCVCGNHDVGNSPTRETMKLYNSSFGDDY 144

Query: 115 RVFIGEQWQILLLDSQ--VFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGC 172
             F       L+++SQ  V      +L+E Q +W+E KL +A ++  ++  H        
Sbjct: 145 YYFWCGGILFLVINSQYFVDSAHVPDLAEKQEKWIEEKLKEANKKRIIVFQHVPWFLKKF 204

Query: 173 SWLDQHSLRNAGELDTVLAKF--PHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPH 230
              DQ+   N+      L KF    VK + CGH H+     ++   +  T +   Q    
Sbjct: 205 DEEDQYFNINSSVRRKWLKKFKKAGVKAIFCGHYHRNGGGIYDNIDVAVTSAVGGQLGND 264

Query: 231 CSNFTLDT 238
            S  T D 
Sbjct: 265 KSEKTGDD 272


>UniRef50_B0T252 Metallophosphoesterase n=5 Tax=Caulobacteraceae RepID=B0T252_CAUSK
          Length = 286

 Score =  141 bits (356), Expect = 3e-32,   Method: Composition-based stats.
 Identities = 42/259 (16%), Positives = 84/259 (32%), Gaps = 41/259 (15%)

Query: 12  EARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSS 71
              ++++Q++D H   +            + +A +E I     +  L++A GDL +D  S
Sbjct: 6   RKPLKLVQVSDIHFGGEHK---------AAVEAAVERINAEAPD--LLIAAGDLTKDGKS 54

Query: 72  AAYQHFAEGIASFRAPCVWLPGNHDFQ-----------PAMYSALQDAGISPAKRVFIGE 120
             +      +     P +  PGNHD              A +   +          +   
Sbjct: 55  TEFDAAQAWLDRLPRPRLVTPGNHDTPFVGPSEILTRLVAPWRRYESRFGGRHNSDWDDP 114

Query: 121 QWQILLLDSQVF-----GVPHGELSEFQLEWLERKL-ADAPERHTLLLLHHHPLPAGCSW 174
           +  +  L+S            G +S  Q+  +   L A AP    +++ HH  +      
Sbjct: 115 RATVATLNSARAFQLRLNWSKGAVSRGQVREVCADLEAAAPGAVKIVVCHHPLIEMLGGP 174

Query: 175 LDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDW---NGRRLLATPSTCVQFKPHC 231
           +    +R         ++   V  +L GHIH      +   +G        T        
Sbjct: 175 MTAK-VRGGTAAAQAFSQ-AGVDLVLTGHIHAPFVHPYPFSDGCTQAVGSGTL------- 225

Query: 232 SNFTLDTIAPGWRTLELHA 250
            +     + P +  +E+  
Sbjct: 226 -SVRERGVPPSFNVIEVDD 243


>UniRef50_B7R2D1 Metallophosphoesterase, calcineurin superfamily n=1
           Tax=Thermococcus sp. AM4 RepID=B7R2D1_9EURY
          Length = 608

 Score =  141 bits (356), Expect = 3e-32,   Method: Composition-based stats.
 Identities = 37/238 (15%), Positives = 79/238 (33%), Gaps = 13/238 (5%)

Query: 27  AQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRA 86
                A       + +  ++  +         ++  GDL      + +    +    +  
Sbjct: 382 GDHRPAHRDDPVPKVFLEIMAQVN--NGSGAFVIDGGDLVYSGRLSEWIDLMKVW-KWNK 438

Query: 87  PCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEW 146
           P    PGNH++Q    +             F+   +  + ++    G     LS  Q E 
Sbjct: 439 PVFLTPGNHEYQGEGKNIFHYLFGPDEDYSFVLGDYVYVFMNDVENGYT---LSSDQWEA 495

Query: 147 LERK--LADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHI 204
           L+    LA+   R  ++++H  P        D    RN+ E    L +  +   +   HI
Sbjct: 496 LKAALKLANETGRRAVIVMHAPPYD-PRPSGDHTMNRNSAEKLLALMREYNAFGIFS-HI 553

Query: 205 HQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTEVHRLA 262
           H     ++ G +++ T        P       +    G+  L +  +G +  ++ R+ 
Sbjct: 554 HLNWYGEYEGVQMVITGGAG---APLYVTDPNEGGFYGYAVLSMGPNGKIGVKLVRVE 608


>UniRef50_C5U614 Metallophosphoesterase n=1 Tax=Methanocaldococcus infernus ME
           RepID=C5U614_9EURY
          Length = 844

 Score =  141 bits (356), Expect = 3e-32,   Method: Composition-based stats.
 Identities = 48/289 (16%), Positives = 95/289 (32%), Gaps = 51/289 (17%)

Query: 4   LLTLPLAGEARVRILQITDTHLFAQKH-EALLG--VNTWESYQAVLEAIRPHQHEFDLIV 60
           LL+   A E  +  + + D HL        + G  +    + +++++ I     +   +V
Sbjct: 15  LLSPAFAEENSIFFVHMADIHLCNDSEVNKIFGGSIPPVTTMKSMVKEILAFHPDT--VV 72

Query: 61  ATGDLA---QDQSSAAYQHFAEGIASF--------RAPCVWLPGNHD------------- 96
            TGD+            Q + E +             P ++ PGNHD             
Sbjct: 73  QTGDIVALADRYDLDTDQRWYELVNKTVVAPIKNAGIPFIFAPGNHDPAAYKLNVNKSDW 132

Query: 97  -FQPAMYSALQDAGISP------AKRVFIGEQWQILLLD---SQVFGVPHGELSEFQLEW 146
            +   +     D G+            +    +  +++D   +   G     L + Q+ W
Sbjct: 133 RYYNGLLLKYVDWGLGANNTDHHTYYSYTIGNYHFVVIDPYETPESGYRAVMLPKDQVNW 192

Query: 147 LERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQ 206
           L+  L +   +  ++  H      G  + D  +     E   +++K+     LL GH H 
Sbjct: 193 LKSDLENNSNKFIIICYHQPL---GSWYNDSIN-----EFLGIISKYKGHIILLAGHTHD 244

Query: 207 ELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELH--ADGT 253
              L WNG       + C  +         D    G+    +    +G+
Sbjct: 245 VRTLYWNGIPEYQDGAACGDWWQTGKTP--DGKPMGYAIYYIKKLDNGS 291


>UniRef50_A8URX6 Putative uncharacterized protein n=1 Tax=Hydrogenivirga sp.
           128-5-R1-1 RepID=A8URX6_9AQUI
          Length = 339

 Score =  141 bits (355), Expect = 3e-32,   Method: Composition-based stats.
 Identities = 42/243 (17%), Positives = 80/243 (32%), Gaps = 37/243 (15%)

Query: 14  RVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAA 73
               + + DTHL+   +         +++   +E I   + + D ++  GDLAQ      
Sbjct: 47  PFNFVVVGDTHLYEMPNHRF-----DKTFSRAIEDILKLRPKPDFVLFIGDLAQFGKVKE 101

Query: 74  YQHFAEGIASF---RAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDS- 129
            +   + +            +PG HD+   M    +          F  +    + ++S 
Sbjct: 102 LEKGKKFLDRLSRAGIKYHIIPGEHDWYLDMGKTWKKM-FGRPYWSFDHKGVHFIGMNSI 160

Query: 130 -------QVFGVPHGE----------------LSEFQLEWLERKLAD-APERHTLLLLHH 165
                       P                   + E QLEWLER +   +P+   ++  H 
Sbjct: 161 LVRDYWTARDMSPWERMLAIAELECHVCGLWGVREKQLEWLERDVKKLSPDTPVVIFTHS 220

Query: 166 HPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCV 225
                   W       +A E+  +L+KF  V  +  GH+HQ +         +   +T  
Sbjct: 221 PLWDYYPRW--NFQTEDAPEVRRILSKFEKVIAI-HGHVHQVVYNRTGNMVHIGNLATAW 277

Query: 226 QFK 228
            + 
Sbjct: 278 PWP 280


>UniRef50_B3QLB7 Metallophosphoesterase n=2 Tax=Chlorobaculum RepID=B3QLB7_CHLP8
          Length = 273

 Score =  140 bits (354), Expect = 4e-32,   Method: Composition-based stats.
 Identities = 42/241 (17%), Positives = 77/241 (31%), Gaps = 33/241 (13%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQ 69
                +R   +TD H   +      G  T    +  +E  +      + ++  GDL   +
Sbjct: 4   TKHDTLRFGIVTDIHYNPETET---GNQTEAGLERCIE--KWTSEGVEFVIQLGDLISRE 58

Query: 70  SSA---AYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILL 126
                       + +A F      + GNH             G+      F     + ++
Sbjct: 59  GPEAEADLIAVRDMLARFSGKVYHVAGNHCLAVPPERYKAIMGLDSLYYTFSSHGTRFIV 118

Query: 127 LDSQVFGVPH------------------------GELSEFQLEWLERKLADA-PERHTLL 161
           LD     + +                        G +   QL+WL ++L  A      ++
Sbjct: 119 LDGMDVSIVNEPQNKADRHLLEYYRDVVKAPFYCGAIGTRQLDWLVKELDLALKNEEPVI 178

Query: 162 LLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATP 221
           + +H PL    +      L N  E+  +L+++P+V   L GH H       NG      P
Sbjct: 179 IFNHLPLLGETTDEKHGLLWNHEEVVAILSRYPNVHACLSGHYHSAAQAMRNGTHFAVLP 238

Query: 222 S 222
           +
Sbjct: 239 A 239


>UniRef50_UPI000185BF3C putative secreted protein n=1 Tax=Corynebacterium amycolatum SK46
           RepID=UPI000185BF3C
          Length = 485

 Score =  140 bits (353), Expect = 5e-32,   Method: Composition-based stats.
 Identities = 59/295 (20%), Positives = 95/295 (32%), Gaps = 54/295 (18%)

Query: 6   TLP-LAGEARVRILQITDTHLFAQKHEALLGVN------------TWESYQAVLEAIRPH 52
           TLP L+G+    I    DTH+    H+ +   N                 +++L+ ++  
Sbjct: 160 TLPTLSGKLLATIALTNDTHIGKPNHDGIRFGNFGLSSEPGEQPFPSMQLESLLKTVKED 219

Query: 53  QHEFDLIVATGDLAQDQSSAAYQHFAEGIASFR---APCVWLPGNHDFQPAM-------- 101
             +   IV  GD         Y  F   +  F           GNHD  P          
Sbjct: 220 GIDT--IVVNGDCTDSNRPEEYDEFLRVMNQFGEMGKQWFVTRGNHDIHPPGLPNINGRR 277

Query: 102 -------YSALQDAGIS-----PAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLER 149
                   + + D             V    + +++ LD+  FG   G ++E Q+  +  
Sbjct: 278 GRDIRKGKTYIPDYFSGLLVPTQQHWVTQVGEVRLIGLDTAEFGYAGGRINERQMRAVRA 337

Query: 150 KLADAPERHTLLLLHHHPLPAG---CSWLDQHSLRN--AGELDTVLAKFPHVKYLLCGHI 204
           +LA  PER T+L  HH                 L    A  L  +LA  P  K +  GH 
Sbjct: 338 ELAQDPERPTILFAHHPITDDAVQSHLGGPSFMLERTQAAALQKILAATPGAKAVFAGHT 397

Query: 205 HQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTEVH 259
           H+      +        +T       C   +      G+  + +H DG+  T   
Sbjct: 398 HRNRRGVAD------VGAT-----DFCERGSSLGYPGGYTRIHIHTDGSQVTYHR 441


>UniRef50_A1ZDF2 Probable beta-galactosidase, putative n=1 Tax=Microscilla marina
           ATCC 23134 RepID=A1ZDF2_9SPHI
          Length = 387

 Score =  140 bits (353), Expect = 5e-32,   Method: Composition-based stats.
 Identities = 41/251 (16%), Positives = 85/251 (33%), Gaps = 40/251 (15%)

Query: 10  AGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQ-- 67
             +     + + D+             NT   +  ++  +         ++  GDL +  
Sbjct: 26  TTQTEFSFVILGDSQF-----------NTPALFNKIINEVAQLSP--AFVIQVGDLIKGK 72

Query: 68  ----DQSSAAYQHFAEGIASFR-APCVWLPGNHDFQPAMYSALQDA--GISPAKRVFIGE 120
               D +   +  F + +      P   +PGNHD      + L             F  +
Sbjct: 73  LQGKDTTMKQWARFKDQLLPLGNTPYYPVPGNHDVLDKKGNPLPYYKQYWGKTNYSFDYK 132

Query: 121 QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPER-HTLLLLHHHPLPAGCSWLDQHS 179
                +L+S        ++ E Q++WLE+ L  A  + H ++  HH            ++
Sbjct: 133 NTHFTILNSN--DGKEAQIGEAQIKWLEKDLKKAQNKAHRMVFFHHPV----------YT 180

Query: 180 LRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTI 239
           L+N  +L ++  K   VK +  GH H     + +G + + T +T        ++      
Sbjct: 181 LKNHEQLHSLFVKHK-VKNVFYGHRHHYEYTERDGIQYVMTNATG----KSGTHELRSGT 235

Query: 240 APGWRTLELHA 250
            P +    +  
Sbjct: 236 FPHFLLATVRD 246


  Database: uniref50.fasta
    Posted date:  Mar 8, 2010 10:38 AM
  Number of letters in database: 1,040,396,356
  Number of sequences in database:  3,077,464
  
Lambda     K      H
   0.313    0.157    0.485 

Lambda     K      H
   0.267   0.0481    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,732,954,365
Number of Sequences: 3077464
Number of extensions: 70203619
Number of successful extensions: 268315
Number of sequences better than 1.0e-01: 250
Number of HSP's better than  0.1 without gapping: 1155
Number of HSP's successfully gapped in prelim test: 5968
Number of HSP's that attempted gapping in prelim test: 252113
Number of HSP's gapped (non-prelim): 9459
length of query: 275
length of database: 1,040,396,356
effective HSP length: 127
effective length of query: 148
effective length of database: 649,558,428
effective search space: 96134647344
effective search space used: 96134647344
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.2 bits)
S2: 92 (39.8 bits)
