Phyre 2 Results for P0ABN5

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Email | l.a.kelley@imperial.ac.uk
Description | P0ABN5
Date | Thu Jan 5 11:15:55 GMT 2012
Unique Job ID | 79e6002ab1ce318c

Summary |

Top model
Image coloured by rainbow N → C terminus
| Close Jmol

Model (left) based on template d1zbsa1
Top template information
Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:BadF/BadG/BcrA/BcrD-like
Confidence and coverage
Confidence: | 54.2% | Coverage: | 9%
39 residues ( 9% of your sequence) have been modelled with 54.2% confidence by the single highest scoring template.
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3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | L | V | V | E | L | I | I | V | L | L | A | I | F | L | G | A | R | L | G | G | I | G | I | G | F | A | G | G | L | G | V | L | V | L | A | A | I | G | V | K | P | G | N | I | P | F | D | V | I | S | I | I | M | A | V | I | A | A | I
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | S | A | M | Q | V | A | G | G | L | D | Y | L | V | H | Q | T | E | K | L | L | R | R | N | P | K | Y | I | T | I | L | A | P | I | V | T | Y | F | L | T | I | F | A | G | T | G | N | I | S | L | A | T | L | P | V | I | A | E | V | A | K
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | E | Q | G | V | K | P | C | R | P | L | S | T | A | V | V | S | A | Q | I | A | I | T | A | S | P | I | S | A | A | V | V | Y | M | S | S | V | M | E | G | H | G | I | S | Y | L | H | L | L | S | V | V | I | P | S | T | L | L | A | V | L
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  | ? | ? | ? |  | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240
Sequence |  | V | M | S | F | L | V | T | M | L | F | N | S | K | L | S | D | D | P | I | Y | R | K | R | L | E | E | G | L | V | E | L | R | G | E | K | Q | I | E | I | K | S | G | A | K | T | S | V | W | L | F | L | L | G | V | V | G | V | V | I | Y
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300
Sequence |  | A | I | I | N | S | P | S | M | G | L | V | E | K | P | L | M | N | T | T | N | A | I | L | I | I | M | L | S | V | A | T | L | T | T | V | I | C | K | V | D | T | D | N | I | L | N | S | S | T | F | K | A | G | M | S | A | C | I | C | I
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360
Sequence |  | L | G | V | A | W | L | G | D | T | F | V | S | N | N | I | D | W | I | K | D | T | A | G | E | V | I | Q | G | H | P | W | L | L | A | V | I | F | F | F | A | S | A | L | L | Y | S | Q | A | A | T | A | K | A | L | M | P | M | A | L | A
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420
Sequence |  | L | N | V | S | P | L | T | A | V | A | S | F | A | A | V | S | G | L | F | I | L | P | T | Y | P | T | L | V | A | A | V | Q | M | D | D | T | G | T | T | R | I | G | K | F | V | F | N | H | P | F | F | I | P | G | T | L | G | V | A | L
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 430 | . | . | .
Sequence |  | A | V | C | F | G | F | V | L | G | S | F | M | L
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  | ? |  | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| d1zbsa1 |

### PDB 1zbs chain A domain 1

Region: 104 - 154
Aligned: 39
Modelled: 51
Confidence: 54.2%
Identity: 26%
Fold: Ribonuclease H-like motif
Superfamily: Actin-like ATPase domain
Family: BadF/BadG/BcrA/BcrD-like

Phyre2
2 |
| c2zv6A_ |

### PDB 2zv6 chain A

Region: 389 - 411
Aligned: 20
Modelled: 23
Confidence: 51.4%
Identity: 40%
PDB header:hydrolase inhibitor
Chain: A: PDB Molecule:serpin b3;
PDBTitle: crystal structure of human squamous cell carcinoma antigen 1

Phyre2
3 |
| d1by7a_ |

### PDB 1by7 chain A

Region: 389 - 411
Aligned: 21
Modelled: 23
Confidence: 51.1%
Identity: 43%
Fold: Serpins
Superfamily: Serpins
Family: Serpins

Phyre2
4 |
| c1sngA_ |

### PDB 1sng chain A

Region: 389 - 411
Aligned: 22
Modelled: 18
Confidence: 48.5%
Identity: 32%
PDB header:hydrolase inhibitor
Chain: A: PDB Molecule:cog4826: serine protease inhibitor;
PDBTitle: structure of a thermophilic serpin in the native state

Phyre2
5 |
| c1q40C_ |

### PDB 1q40 chain C

Region: 376 - 402
Aligned: 27
Modelled: 27
Confidence: 39.7%
Identity: 37%
PDB header:translation
Chain: C: PDB Molecule:mrna transport regulator mtr2;
PDBTitle: crystal structure of the c. albicans mtr2-mex67 m domain complex

Phyre2
6 |
| d1q42a_ |

### PDB 1q42 chain A

Region: 376 - 402
Aligned: 27
Modelled: 27
Confidence: 37.9%
Identity: 37%
Fold: Cystatin-like
Superfamily: NTF2-like
Family: NTF2-like

Phyre2
7 |
| c2uv1B_ |

### PDB 2uv1 chain B

Region: 195 - 206
Aligned: 12
Modelled: 12
Confidence: 29.7%
Identity: 33%
PDB header:inhibitor
Chain: B: PDB Molecule:host-nuclease inhibitor protein gam;
PDBTitle: hexagonal crystal form of gams from bacteriophage lambda.

Phyre2
8 |
| c3o8jH_ |

### PDB 3o8j chain H

Region: 39 - 159
Aligned: 120
Modelled: 121
Confidence: 29.1%
Identity: 13%
PDB header:transferase
Chain: H: PDB Molecule:2-methylcitrate synthase;
PDBTitle: crystal structure of 2-methylcitrate synthase (prpc) from salmonella2 typhimurium

Phyre2
9 |
| c2oayA_ |

### PDB 2oay chain A

Region: 389 - 411
Aligned: 23
Modelled: 23
Confidence: 28.7%
Identity: 22%
PDB header:immune system,hydrolase inhibitor
Chain: A: PDB Molecule:plasma protease c1 inhibitor;
PDBTitle: crystal structure of latent human c1-inhibitor

Phyre2
10 |
| d1u5ta1 |

### PDB 1u5t chain A domain 1

Region: 185 - 206
Aligned: 21
Modelled: 22
Confidence: 28.5%
Identity: 24%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: "Winged helix" DNA-binding domain
Family: Vacuolar sorting protein domain

Phyre2
11 |
| c3le2A_ |

### PDB 3le2 chain A

Region: 389 - 411
Aligned: 23
Modelled: 23
Confidence: 27.9%
Identity: 43%
PDB header:hydrolase
Chain: A: PDB Molecule:serpin-zx;
PDBTitle: structure of arabidopsis atserpin1. native stressed conformation

Phyre2
12 |
| c3ozqA_ |

### PDB 3ozq chain A

Region: 389 - 411
Aligned: 23
Modelled: 23
Confidence: 27.5%
Identity: 30%
PDB header:hydrolase inhibitor
Chain: A: PDB Molecule:serpin48;
PDBTitle: crystal structure of serpin48, which is a highly specific serpin in2 the insect tenebrio molitor

Phyre2
13 |
| c3pzfA_ |

### PDB 3pzf chain A

Region: 389 - 411
Aligned: 23
Modelled: 23
Confidence: 26.2%
Identity: 39%
PDB header:hydrolase inhibitor
Chain: A: PDB Molecule:serpin 2;
PDBTitle: 1.75a resolution structure of serpin-2 from anopheles gambiae

Phyre2
14 |
| c2vh4B_ |

### PDB 2vh4 chain B

Region: 389 - 411
Aligned: 23
Modelled: 23
Confidence: 25.8%
Identity: 35%
PDB header:hydrolase inhibitor
Chain: B: PDB Molecule:tengpin;
PDBTitle: structure of a loop c-sheet serpin polymer

Phyre2
15 |
| d1imva_ |

### PDB 1imv chain A

Region: 389 - 411
Aligned: 23
Modelled: 23
Confidence: 25.7%
Identity: 22%
Fold: Serpins
Superfamily: Serpins
Family: Serpins

Phyre2
16 |
| c2r9yA_ |

### PDB 2r9y chain A

Region: 389 - 411
Aligned: 23
Modelled: 23
Confidence: 25.6%
Identity: 22%
PDB header:hydrolase inhibitor
Chain: A: PDB Molecule:alpha-2-antiplasmin;
PDBTitle: structure of antiplasmin

Phyre2
17 |
| d2nwwa1 |

### PDB 2nww chain A domain 1

Region: 110 - 179
Aligned: 70
Modelled: 70
Confidence: 25.2%
Identity: 24%
Fold: Proton glutamate symport protein
Superfamily: Proton glutamate symport protein
Family: Proton glutamate symport protein

Phyre2
18 |
| d1k82a1 |

### PDB 1k82 chain A domain 1

Region: 74 - 129
Aligned: 43
Modelled: 56
Confidence: 24.6%
Identity: 26%
Fold: S13-like H2TH domain
Superfamily: S13-like H2TH domain
Family: Middle domain of MutM-like DNA repair proteins

Phyre2
19 |
| c2dutC_ |

### PDB 2dut chain C

Region: 389 - 411
Aligned: 23
Modelled: 23
Confidence: 24.0%
Identity: 43%
PDB header:hydrolase inhibitor
Chain: C: PDB Molecule:heterochromatin-associated protein ment;
PDBTitle: crystal structure of a m-loop deletion variant of ment in2 the native conformation

Phyre2
20 |
| d1af7a2 |

### PDB 1af7 chain A domain 2

Region: 70 - 125
Aligned: 47
Modelled: 56
Confidence: 23.9%
Identity: 17%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: Chemotaxis receptor methyltransferase CheR, C-terminal domain

Phyre2
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Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | d1zbsa1 |
|  | 54.2 | 26 | Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:BadF/BadG/BcrA/BcrD-like
2 | c2zv6A_ |
|  | 51.4 | 40 | PDB header:hydrolase inhibitor Chain: A: PDB Molecule:serpin b3; PDBTitle: crystal structure of human squamous cell carcinoma antigen 1
3 | d1by7a_ |
|  | 51.1 | 43 | Fold:Serpins Superfamily:Serpins Family:Serpins
4 | c1sngA_ |
|  | 48.5 | 32 | PDB header:hydrolase inhibitor Chain: A: PDB Molecule:cog4826: serine protease inhibitor; PDBTitle: structure of a thermophilic serpin in the native state
5 | c1q40C_ |
|  | 39.7 | 37 | PDB header:translation Chain: C: PDB Molecule:mrna transport regulator mtr2; PDBTitle: crystal structure of the c. albicans mtr2-mex67 m domain complex
6 | d1q42a_ |
|  | 37.9 | 37 | Fold:Cystatin-like Superfamily:NTF2-like Family:NTF2-like
7 | c2uv1B_ |
|  | 29.7 | 33 | PDB header:inhibitor Chain: B: PDB Molecule:host-nuclease inhibitor protein gam; PDBTitle: hexagonal crystal form of gams from bacteriophage lambda.
8 | c3o8jH_ |
|  | 29.1 | 13 | PDB header:transferase Chain: H: PDB Molecule:2-methylcitrate synthase; PDBTitle: crystal structure of 2-methylcitrate synthase (prpc) from salmonella2 typhimurium
9 | c2oayA_ |
|  | 28.7 | 22 | PDB header:immune system,hydrolase inhibitor Chain: A: PDB Molecule:plasma protease c1 inhibitor; PDBTitle: crystal structure of latent human c1-inhibitor
10 | d1u5ta1 |
|  | 28.5 | 24 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Vacuolar sorting protein domain
11 | c3le2A_ |
|  | 27.9 | 43 | PDB header:hydrolase Chain: A: PDB Molecule:serpin-zx; PDBTitle: structure of arabidopsis atserpin1. native stressed conformation
12 | c3ozqA_ |
|  | 27.5 | 30 | PDB header:hydrolase inhibitor Chain: A: PDB Molecule:serpin48; PDBTitle: crystal structure of serpin48, which is a highly specific serpin in2 the insect tenebrio molitor
13 | c3pzfA_ |
|  | 26.2 | 39 | PDB header:hydrolase inhibitor Chain: A: PDB Molecule:serpin 2; PDBTitle: 1.75a resolution structure of serpin-2 from anopheles gambiae
14 | c2vh4B_ |
|  | 25.8 | 35 | PDB header:hydrolase inhibitor Chain: B: PDB Molecule:tengpin; PDBTitle: structure of a loop c-sheet serpin polymer
15 | d1imva_ |
|  | 25.7 | 22 | Fold:Serpins Superfamily:Serpins Family:Serpins
16 | c2r9yA_ |
|  | 25.6 | 22 | PDB header:hydrolase inhibitor Chain: A: PDB Molecule:alpha-2-antiplasmin; PDBTitle: structure of antiplasmin
17 | d2nwwa1 |
|  | 25.2 | 24 | Fold:Proton glutamate symport protein Superfamily:Proton glutamate symport protein Family:Proton glutamate symport protein
18 | d1k82a1 |
|  | 24.6 | 26 | Fold:S13-like H2TH domain Superfamily:S13-like H2TH domain Family:Middle domain of MutM-like DNA repair proteins
19 | c2dutC_ |
|  | 24.0 | 43 | PDB header:hydrolase inhibitor Chain: C: PDB Molecule:heterochromatin-associated protein ment; PDBTitle: crystal structure of a m-loop deletion variant of ment in2 the native conformation
20 | d1af7a2 |
|  | 23.9 | 17 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Chemotaxis receptor methyltransferase CheR, C-terminal domain
21 | c3druC_ |
| not modelled | 23.3 | 35 | PDB header:hydrolase inhibitor Chain: C: PDB Molecule:alpha-1-antitrypsin; PDBTitle: crystal structure of gly117phe alpha1-antitrypsin
22 | c3f5nA_ |
| not modelled | 23.0 | 22 | PDB header:hydrolase inhibitor Chain: A: PDB Molecule:neuroserpin; PDBTitle: structure of native human neuroserpin
23 | c3crcB_ |
| not modelled | 23.0 | 27 | PDB header:hydrolase Chain: B: PDB Molecule:protein mazg; PDBTitle: crystal structure of escherichia coli mazg, the regulator2 of nutritional stress response
24 | d2b5ti1 |
| not modelled | 22.4 | 35 | Fold:Serpins Superfamily:Serpins Family:Serpins
25 | c3b8eB_ |
| not modelled | 21.6 | 20 | PDB header:hydrolase/transport protein Chain: B: PDB Molecule:sodium/potassium-transporting atpase subunit PDBTitle: crystal structure of the sodium-potassium pump
26 | c1jmoA_ |
| not modelled | 21.1 | 39 | PDB header:blood clotting Chain: A: PDB Molecule:heparin cofactor ii; PDBTitle: crystal structure of the heparin cofactor ii-s195a thrombin complex
27 | d1jmja_ |
| not modelled | 20.8 | 39 | Fold:Serpins Superfamily:Serpins Family:Serpins
28 | d1ee8a1 |
| not modelled | 20.7 | 34 | Fold:S13-like H2TH domain Superfamily:S13-like H2TH domain Family:Middle domain of MutM-like DNA repair proteins
29 | c2v95A_ |
| not modelled | 20.2 | 30 | PDB header:transport protein Chain: A: PDB Molecule:corticosteroid-binding globulin; PDBTitle: struture of corticosteroid-binding globulin in complex with2 cortisol
30 | c2kluA_ |
| not modelled | 19.2 | 31 | PDB header:immune system, membrane protein Chain: A: PDB Molecule:t-cell surface glycoprotein cd4; PDBTitle: nmr structure of the transmembrane and cytoplasmic domains2 of human cd4
31 | c3h5cA_ |
| not modelled | 18.4 | 26 | PDB header:hydrolase inhibitor/blood clotting Chain: A: PDB Molecule:protein z-dependent protease inhibitor; PDBTitle: x-ray structure of protein z-protein z inhibitor complex
32 | d1tdza1 |
| not modelled | 18.3 | 37 | Fold:S13-like H2TH domain Superfamily:S13-like H2TH domain Family:Middle domain of MutM-like DNA repair proteins
33 | c2xpiE_ |
| not modelled | 17.7 | 56 | PDB header:cell cycle Chain: E: PDB Molecule:anaphase-promoting complex subunit hcn1 hcn1/cdc26,20s PDBTitle: crystal structure of apc/c hetero-tetramer cut9-hcn1
34 | d1k9oi_ |
| not modelled | 17.0 | 22 | Fold:Serpins Superfamily:Serpins Family:Serpins
35 | c2wxxC_ |
| not modelled | 16.9 | 9 | PDB header:hormone Chain: C: PDB Molecule:angiotensinogen; PDBTitle: crystal structure of mouse angiotensinogen in the oxidised form
36 | c3f1sA_ |
| not modelled | 16.0 | 26 | PDB header:hydrolase inhibitor/hydrolase Chain: A: PDB Molecule:protein z-dependent protease inhibitor; PDBTitle: crystal structure of protein z complexed with protein z-dependent2 inhibitor
37 | d1seka_ |
| not modelled | 15.9 | 30 | Fold:Serpins Superfamily:Serpins Family:Serpins
38 | d2gh1a1 |
| not modelled | 15.6 | 29 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:BC2162-like
39 | d1klva_ |
| not modelled | 15.5 | 20 | Fold:beta-Grasp (ubiquitin-like) Superfamily:Ubiquitin-like Family:GABARAP-like
40 | d2ezwa1 |
| not modelled | 15.2 | 43 | Fold:Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit Superfamily:Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit Family:Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit
41 | c3djlA_ |
| not modelled | 14.1 | 36 | PDB header:oxidoreductase Chain: A: PDB Molecule:protein aidb; PDBTitle: crystal structure of alkylation response protein e. coli aidb
42 | d1rzhh2 |
| not modelled | 13.3 | 46 | Fold:Single transmembrane helix Superfamily:Photosystem II reaction centre subunit H, transmembrane region Family:Photosystem II reaction centre subunit H, transmembrane region
43 | d1xqga_ |
| not modelled | 13.2 | 26 | Fold:Serpins Superfamily:Serpins Family:Serpins
44 | c2ceoA_ |
| not modelled | 13.1 | 17 | PDB header:transport Chain: A: PDB Molecule:thyroxine-binding globulin; PDBTitle: thyroxine-binding globulin complex with thyroxine
45 | d1qlpa_ |
| not modelled | 13.0 | 35 | Fold:Serpins Superfamily:Serpins Family:Serpins
46 | c2ol2A_ |
| not modelled | 13.0 | 57 | PDB header:hydrolase inhibitor Chain: A: PDB Molecule:plasma serine protease inhibitor; PDBTitle: high resolution structure of native pci in space group p21
47 | c3ndaA_ |
| not modelled | 12.6 | 43 | PDB header:hydrolase inhibitor Chain: A: PDB Molecule:serpin-2; PDBTitle: crystal structure of serpin from tick ixodes ricinus
48 | d1l9bh2 |
| not modelled | 12.1 | 46 | Fold:Single transmembrane helix Superfamily:Photosystem II reaction centre subunit H, transmembrane region Family:Photosystem II reaction centre subunit H, transmembrane region
49 | d1lj5a_ |
| not modelled | 12.0 | 22 | Fold:Serpins Superfamily:Serpins Family:Serpins
50 | c2ou2A_ |
| not modelled | 11.8 | 33 | PDB header:transferase Chain: A: PDB Molecule:histone acetyltransferase htatip; PDBTitle: acetyltransferase domain of human hiv-1 tat interacting2 protein, 60kda, isoform 3
51 | c1yxaB_ |
| not modelled | 10.6 | 39 | PDB header:hydrolase inhibitor Chain: B: PDB Molecule:serine (or cysteine) proteinase inhibitor, clade a, member PDBTitle: serpina3n, a murine orthologue of human antichymotrypsin
52 | c2hi9C_ |
| not modelled | 10.5 | 41 | PDB header:hydrolase inhibitor Chain: C: PDB Molecule:plasma serine protease inhibitor; PDBTitle: crystal structure of human native protein c inhibitor
53 | d1vzsa_ |
| not modelled | 10.1 | 15 | Fold:Mitochondrial ATP synthase coupling factor 6 Superfamily:Mitochondrial ATP synthase coupling factor 6 Family:Mitochondrial ATP synthase coupling factor 6
54 | c2zmeA_ |
| not modelled | 10.0 | 10 | PDB header:protein transport Chain: A: PDB Molecule:vacuolar-sorting protein snf8; PDBTitle: integrated structural and functional model of the human escrt-ii2 complex
55 | c2zq5A_ |
| not modelled | 10.0 | 23 | PDB header:transferase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of sulfotransferase stf1 from2 mycobacterium tuberculosis h37rv (type1 form)
56 | d1jb0f_ |
| not modelled | 10.0 | 32 | Fold:Single transmembrane helix Superfamily:Subunit III of photosystem I reaction centre, PsaF Family:Subunit III of photosystem I reaction centre, PsaF
57 | d1atta_ |
| not modelled | 9.8 | 30 | Fold:Serpins Superfamily:Serpins Family:Serpins
58 | d1zxoa2 |
| not modelled | 9.6 | 15 | Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:BadF/BadG/BcrA/BcrD-like
59 | d2rcrh2 |
| not modelled | 9.4 | 46 | Fold:Single transmembrane helix Superfamily:Photosystem II reaction centre subunit H, transmembrane region Family:Photosystem II reaction centre subunit H, transmembrane region
60 | d1r7la_ |
| not modelled | 9.4 | 18 | Fold:Bacillus phage protein Superfamily:Bacillus phage protein Family:Bacillus phage protein
61 | d2clyc1 |
| not modelled | 9.4 | 19 | Fold:Mitochondrial ATP synthase coupling factor 6 Superfamily:Mitochondrial ATP synthase coupling factor 6 Family:Mitochondrial ATP synthase coupling factor 6
62 | c3if4C_ |
| not modelled | 9.4 | 32 | PDB header:structural genomics, unknown function Chain: C: PDB Molecule:integron cassette protein hfx_cass5; PDBTitle: structure from the mobile metagenome of north west arm2 sewage outfall: integron cassette protein hfx_cass5
63 | c2x0bD_ |
| not modelled | 9.3 | 14 | PDB header:hydrolase/hormone Chain: D: PDB Molecule:angiotensinogen; PDBTitle: crystal structure of human angiotensinogen complexed with renin
64 | d2ozua1 |
| not modelled | 9.2 | 29 | Fold:Acyl-CoA N-acyltransferases (Nat) Superfamily:Acyl-CoA N-acyltransferases (Nat) Family:N-acetyl transferase, NAT
65 | d2giva1 |
| not modelled | 9.2 | 26 | Fold:Acyl-CoA N-acyltransferases (Nat) Superfamily:Acyl-CoA N-acyltransferases (Nat) Family:N-acetyl transferase, NAT
66 | c2givA_ |
| not modelled | 9.2 | 26 | PDB header:transferase Chain: A: PDB Molecule:probable histone acetyltransferase myst1; PDBTitle: human myst histone acetyltransferase 1
67 | c2o01F_ |
| not modelled | 9.2 | 29 | PDB header:photosynthesis Chain: F: PDB Molecule:photosystem i reaction center subunit iii, PDBTitle: the structure of a plant photosystem i supercomplex at 3.42 angstrom resolution
68 | c2kjgA_ |
| not modelled | 8.7 | 43 | PDB header:metal binding protein Chain: A: PDB Molecule:archaeal protein sso6904; PDBTitle: solution structure of an archaeal protein sso6904 from2 hyperthermophilic sulfolobus solfataricus
69 | d1ioma_ |
| not modelled | 8.6 | 12 | Fold:Citrate synthase Superfamily:Citrate synthase Family:Citrate synthase
70 | c3f02C_ |
| not modelled | 8.6 | 44 | PDB header:hydrolase inhibitor Chain: C: PDB Molecule:neuroserpin; PDBTitle: cleaved human neuroserpin
71 | d1st6a7 |
| not modelled | 8.6 | 29 | Fold:Four-helical up-and-down bundle Superfamily:alpha-catenin/vinculin-like Family:alpha-catenin/vinculin
72 | c9paiB_ |
| not modelled | 8.5 | 22 | PDB header:hydrolase inhibitor Chain: B: PDB Molecule:protein (plasminogen activator inhibitor-1) residues 365- PDBTitle: cleaved substrate variant of plasminogen activator inhibitor-1
73 | d1q90d_ |
| not modelled | 8.3 | 18 | Fold:a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) Superfamily:a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) Family:a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
74 | c7apiB_ |
| not modelled | 8.3 | 44 | PDB header:proteinase inhibitor Chain: B: PDB Molecule:alpha 1-antitrypsin; PDBTitle: the s variant of human alpha1-antitrypsin, structure and implications2 for function and metabolism
75 | c1qmnA_ |
| not modelled | 8.3 | 30 | PDB header:serpin Chain: A: PDB Molecule:alpha-1-antichymotrypsin; PDBTitle: alpha1-antichymotrypsin serpin in the delta conformation2 (partial loop insertion)
76 | d1h6ga2 |
| not modelled | 8.2 | 14 | Fold:Four-helical up-and-down bundle Superfamily:alpha-catenin/vinculin-like Family:alpha-catenin/vinculin
77 | d1fy7a_ |
| not modelled | 8.2 | 29 | Fold:Acyl-CoA N-acyltransferases (Nat) Superfamily:Acyl-CoA N-acyltransferases (Nat) Family:N-acetyl transferase, NAT
78 | c3aqpB_ |
| not modelled | 8.0 | 15 | PDB header:membrane protein Chain: B: PDB Molecule:probable secdf protein-export membrane protein; PDBTitle: crystal structure of secdf, a translocon-associated membrane protein,2 from thermus thrmophilus
79 | c2h4qB_ |
| not modelled | 7.9 | 42 | PDB header:hydrolase inhibitor Chain: B: PDB Molecule:heterochromatin-associated protein ment; PDBTitle: crystal structure of a m-loop deletion variant of ment in2 the cleaved conformation
80 | c3dmpD_ |
| not modelled | 7.7 | 27 | PDB header:transferase Chain: D: PDB Molecule:uracil phosphoribosyltransferase; PDBTitle: 2.6 a crystal structure of uracil phosphoribosyltransferase2 from burkholderia pseudomallei
81 | c3ixzB_ |
| not modelled | 7.7 | 10 | PDB header:hydrolase Chain: B: PDB Molecule:potassium-transporting atpase subunit beta; PDBTitle: pig gastric h+/k+-atpase complexed with aluminium fluoride
82 | d1niga_ |
| not modelled | 7.6 | 22 | Fold:Ferritin-like Superfamily:Cobalamin adenosyltransferase-like Family:Hypothetical protein Ta1238
83 | c2yxhB_ |
| not modelled | 7.5 | 21 | PDB header:structural genomics, unknown function Chain: B: PDB Molecule:mazg-related protein; PDBTitle: crystal structure of mazg-related protein from thermotoga maritima
84 | c1jjoE_ |
| not modelled | 7.4 | 33 | PDB header:signaling protein Chain: E: PDB Molecule:neuroserpin; PDBTitle: crystal structure of mouse neuroserpin (cleaved form)
85 | c2auhB_ |
| not modelled | 7.3 | 33 | PDB header:transferase/signaling protein Chain: B: PDB Molecule:growth factor receptor-bound protein 14; PDBTitle: crystal structure of the grb14 bps region in complex with2 the insulin receptor tyrosine kinase
86 | c2l09A_ |
| not modelled | 7.2 | 16 | PDB header:oxidoreductase Chain: A: PDB Molecule:asr4154 protein; PDBTitle: solution nmr structure of protein asr4154 from nostoc sp. pcc71202 northeast structural genomics consortium target id nsr143
87 | c3cwbT_ |
| not modelled | 7.1 | 29 | PDB header:oxidoreductase Chain: T: PDB Molecule:mitochondrial ubiquinol-cytochrome c reductase ubiquinone- PDBTitle: chicken cytochrome bc1 complex inhibited by an iodinated analogue of2 the polyketide crocacin-d
88 | c2oixA_ |
| not modelled | 7.0 | 24 | PDB header:hydrolase Chain: A: PDB Molecule:xanthomonas outer protein d; PDBTitle: xanthomonas xopd c470a mutant
89 | c3cuqA_ |
| not modelled | 7.0 | 10 | PDB header:protein transport Chain: A: PDB Molecule:vacuolar-sorting protein snf8; PDBTitle: integrated structural and functional model of the human escrt-ii2 complex
90 | c2kruA_ |
| not modelled | 6.9 | 19 | PDB header:oxidoreductase Chain: A: PDB Molecule:light-independent protochlorophyllide reductase PDBTitle: solution nmr structure of the pcp_red domain of light-2 independent protochlorophyllide reductase subunit b from3 chlorobium tepidum. northeast structural genomics4 consortium target ctr69a (casp target)
91 | d1im8a_ |
| not modelled | 6.9 | 15 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Hypothetical protein HI0319 (YecO)
92 | d2q7ra1 |
| not modelled | 6.9 | 11 | Fold:MAPEG domain-like Superfamily:MAPEG domain-like Family:MAPEG domain
93 | c2d7cD_ |
| not modelled | 6.6 | 27 | PDB header:protein transport Chain: D: PDB Molecule:rab11 family-interacting protein 3; PDBTitle: crystal structure of human rab11 in complex with fip3 rab-2 binding domain
94 | c1hleB_ |
| not modelled | 6.6 | 50 | PDB header:hydrolase inhibitor(serine proteinase) Chain: B: PDB Molecule:horse leukocyte elastase inhibitor; PDBTitle: crystal structure of cleaved equine leucocyte elastase2 inhibitor determined at 1.95 angstroms resolution
95 | c1zxoB_ |
| not modelled | 6.5 | 24 | PDB header:unknown function Chain: B: PDB Molecule:conserved hypothetical protein q8a1p1; PDBTitle: x-ray crystal structure of protein q8a1p1 from bacteroides2 thetaiotaomicron. northeast structural genomics consortium3 target btr25.
96 | d1k5ja_ |
| not modelled | 6.5 | 17 | Fold:Nucleoplasmin-like/VP (viral coat and capsid proteins) Superfamily:Nucleoplasmin-like core domain Family:Nucleoplasmin-like core domain
97 | d1knza_ |
| not modelled | 6.4 | 42 | Fold:NSP3 homodimer Superfamily:NSP3 homodimer Family:NSP3 homodimer
98 | c3hefB_ |
| not modelled | 6.3 | 14 | PDB header:viral protein Chain: B: PDB Molecule:gene 1 protein; PDBTitle: crystal structure of the bacteriophage sf6 terminase small2 subunit
99 | d1a59a_ |
| not modelled | 6.3 | 17 | Fold:Citrate synthase Superfamily:Citrate synthase Family:Citrate synthase

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0