BLASTP 2.2.22 [Sep-27-2009]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= batch____
         (433 letters)

Database: uniref50.fasta 
           3,077,464 sequences; 1,040,396,356 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_A1JIN9 Anaerobic C4-dicarboxylate transporter n=79 Tax=...   467   e-130
UniRef50_Q7MDX2 Anaerobic C4-dicarboxylate transporter n=104 Tax...   460   e-128
UniRef50_A7I3J6 Anaerobic C4-dicarboxylate transporter DcuA n=8 ...   456   e-127
UniRef50_C9R1M8 Anaerobic C4-dicarboxylate membrane transporter ...   456   e-127
UniRef50_B4CX44 Anaerobic c4-dicarboxylate antiporter, Dcu famil...   451   e-125
UniRef50_P44855 Anaerobic C4-dicarboxylate transporter dcuB n=16...   451   e-125
UniRef50_C8N6Y6 Anaerobic C4-dicarboxylate transporter DcuB n=1 ...   441   e-122
UniRef50_C6CN04 Anaerobic c4-dicarboxylate antiporter, Dcu famil...   440   e-122
UniRef50_Q5HVA4 Anaerobic C4-dicarboxylate membrane transporter ...   438   e-121
UniRef50_Q5E4K5 Anaerobic C4-dicarboxylate transporter n=16 Tax=...   433   e-120
UniRef50_Q9ZLC0 Anaerobic C4-dicarboxylate transporter dcuA n=22...   432   e-119
UniRef50_P0ABP1 Anaerobic C4-dicarboxylate transporter dcuB n=13...   430   e-119
UniRef50_B4UMD4 Anaerobic c4-dicarboxylate antiporter, Dcu famil...   428   e-118
UniRef50_Q7NRZ2 Anaerobic C4-dicarboxylate membrane transporter ...   426   e-118
UniRef50_B4TYZ8 Anaerobic C4-dicarboxylate transporter DcuA n=30...   425   e-117
UniRef50_D1P157 Anaerobic C4-dicarboxylate transporter DcuB n=2 ...   424   e-117
UniRef50_B6EGF2 Anaerobic c4-dicarboxylate transporter DcuB n=1 ...   401   e-110
UniRef50_C3JGC7 C4-dicarboxylate membrane transporter n=2 Tax=Rh...   395   e-108
UniRef50_B1LPU8 Anaerobic C4-dicarboxylate membrane transporter,...   384   e-105
UniRef50_D2TK06 Anaerobic C4-dicarboxylate transporter n=1 Tax=C...   382   e-104
UniRef50_UPI00019F11D6 anaerobic c4-dicarboxylate antiporter, Dc...   377   e-103
UniRef50_A7GZH5 Anaerobic C4-dicarboxylate transporter DcuA n=4 ...   368   e-100
UniRef50_A4N2Y1 Anaerobic C4-dicarboxylate transporter n=1 Tax=H...   364   3e-99
UniRef50_Q8CMX9 Anaerobic dicarboxylate transport n=11 Tax=Staph...   329   1e-88
UniRef50_C5EXL5 Anaerobic C4-dicarboxylate transporter n=2 Tax=P...   328   2e-88
UniRef50_A7ZC15 Anaerobic C4-dicarboxylate membrane transporter ...   282   3e-74
UniRef50_C6MSZ8 Anaerobic c4-dicarboxylate antiporter, Dcu famil...   270   5e-71
UniRef50_Q2EX27 DcuA (Fragment) n=20 Tax=Bacteria RepID=Q2EX27_E...   218   4e-55
UniRef50_UPI0001854D97 anaerobic C4-dicarboxylate transporter n=...   170   1e-40
UniRef50_P40684 Anaerobic C4-dicarboxylate transporter dcuA (Fra...   137   7e-31
UniRef50_UPI00019127C3 anaerobic C4-dicarboxylate transporter n=...   107   9e-22
UniRef50_Q1CLI8 Anaerobic C4-dicarboxylate transporter n=8 Tax=Y...    95   7e-18
UniRef50_C3HV44 Anaerobic C4-dicarboxylate transporter dcuB n=1 ...    86   4e-15
UniRef50_UPI00019127C2 anaerobic C4-dicarboxylate transporter n=...    44   0.012
UniRef50_P25360 Inorganic phosphate transporter PHO87 n=19 Tax=S...    43   0.028
UniRef50_Q03HQ5 C4-dicarboxylate transporter n=5 Tax=Bacteria Re...    42   0.036
UniRef50_C3KGP7 MIP04527p (Fragment) n=9 Tax=Sophophora RepID=C3...    42   0.053
UniRef50_C4XIX1 Arsenical pump membrane protein n=1 Tax=Desulfov...    41   0.099

>UniRef50_A1JIN9 Anaerobic C4-dicarboxylate transporter n=79 Tax=Bacteria
           RepID=A1JIN9_YERE8
          Length = 433

 Score =  467 bits (1202), Expect = e-130,   Method: Composition-based stats.
 Identities = 370/433 (85%), Positives = 401/433 (92%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAAIGVKPGNIPFDVISIIMAVIAAI 60
           M+ VEL+IVLLAIFLGARLGGIGIGFAGG+GVLVLA IGVKPG+IPFDVISIIMAVIAAI
Sbjct: 1   MIAVELVIVLLAIFLGARLGGIGIGFAGGIGVLVLAIIGVKPGSIPFDVISIIMAVIAAI 60

Query: 61  SAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAK 120
           SAMQVAGG+DYLV QTEKLLR+NPK+ITILAP+VTYFLTIFAGTGNISL+ LPVIAEVAK
Sbjct: 61  SAMQVAGGMDYLVQQTEKLLRKNPKHITILAPLVTYFLTIFAGTGNISLSALPVIAEVAK 120

Query: 121 EQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAVL 180
           EQG+KPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHG+SYLHLL +VIPSTLLAV 
Sbjct: 121 EQGIKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGVSYLHLLMIVIPSTLLAVF 180

Query: 181 VMSFLVTMLFNSKLSDDPIYRKRLEEGLVELRGEKQIEIKSGAKTSVWLFLLGVVGVVIY 240
           VMS +V+  FNSKLSDDPIY KRLEEGLV LRG+    IK  AKTSV LFL GV+ VV Y
Sbjct: 181 VMSLIVSWCFNSKLSDDPIYIKRLEEGLVTLRGDTVKVIKPRAKTSVLLFLAGVLCVVAY 240

Query: 241 AIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSACICI 300
           AIINSPS+GLV  PLMNTTNAILIIMLSVAT+TT++C VDTD+ILNSSTFKAGMSACICI
Sbjct: 241 AIINSPSVGLVATPLMNTTNAILIIMLSVATITTMVCSVDTDSILNSSTFKAGMSACICI 300

Query: 301 LGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPMALA 360
           LGVAWLGDTFV +N+DWIK+TAG +IQ H WLLAVIFFF SALLYSQAATAKALMPMA+A
Sbjct: 301 LGVAWLGDTFVQHNLDWIKETAGSLIQAHSWLLAVIFFFCSALLYSQAATAKALMPMAMA 360

Query: 361 LNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLGVAL 420
           LNVSPL A+ASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIG+FVFNHPFFIPGT+GVAL
Sbjct: 361 LNVSPLAAIASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGRFVFNHPFFIPGTIGVAL 420

Query: 421 AVCFGFVLGSFML 433
           AVCFGFV+G  +L
Sbjct: 421 AVCFGFVMGGLVL 433


>UniRef50_Q7MDX2 Anaerobic C4-dicarboxylate transporter n=104 Tax=cellular organisms
           RepID=Q7MDX2_VIBVY
          Length = 467

 Score =  460 bits (1185), Expect = e-128,   Method: Composition-based stats.
 Identities = 155/428 (36%), Positives = 250/428 (58%), Gaps = 10/428 (2%)

Query: 15  LGARLGGIGIGFAGGLGVLVLAA-IGVKPGNIPFDVISIIMAVIAAISAMQVAGGLDYLV 73
           +G+R GGIG+G   G+G+++      + P + P  V+ II+AV+   S ++ AGGL Y++
Sbjct: 40  IGSRYGGIGLGVVSGIGLVIEVFVFKMPPTSPPVTVMLIILAVVTCASILEAAGGLKYML 99

Query: 74  HQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAKEQGVKPCRPLSTA 133
              E++LR+NPK +T++AP VTY +T   GTG+   + +P+I +VA + G++P RP++ A
Sbjct: 100 QVAERMLRKNPKRVTLIAPFVTYTMTFMLGTGHAVYSIMPIIGDVALKNGIRPERPMAAA 159

Query: 134 VVSAQIAITASPISAAVVYMSSVME--GHGISYLHLLSVVIPSTLLAVLVMSFLVTMLFN 191
            V++QIAITASPISAAVVY  + +    H I+ L +L V +P+TL   L+MS L +M   
Sbjct: 160 SVASQIAITASPISAAVVYYLAQLSDINHEITLLSILLVTVPATLFGTLLMS-LYSMKRG 218

Query: 192 SKLSDDPIYRKRLEEGLVELR------GEKQIEIKSGAKTSVWLFLLGVVGVVIYAIINS 245
            +L DDP Y+ RL++ +   +            + + A+ SV LF+L ++ +V+ A+I  
Sbjct: 219 KELEDDPEYQARLKDPVWREKILNTTATSLDEHLPAAARNSVLLFILSILTIVVIAMIPE 278

Query: 246 PSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSACICILGVAW 305
             +       ++    I ++ML    +  +  K D  ++ N   FK+GM A I I G+AW
Sbjct: 279 VRIIGEGTKPISMAVVIQMMMLCFGGIILLATKTDPRSVPNGVVFKSGMVAAIAIFGIAW 338

Query: 306 LGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPMALALNVSP 365
           + DT+    +   K    E++  +PW  A+  F  S ++ SQAA A+ ++P+ L L + P
Sbjct: 339 MSDTYFQYAMPQFKSGIVEMVNNYPWTFALALFIVSVVVNSQAAVARMMLPVGLGLGLEP 398

Query: 366 LTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLGVALAVCFG 425
              V    A+ G F +P YP+ +A V  D+TGTT+IGK+ FNH F   G +GV  A C G
Sbjct: 399 ALLVGLMPALYGYFFIPNYPSDIATVNFDNTGTTKIGKWYFNHSFMSVGLIGVIGACCLG 458

Query: 426 FVLGSFML 433
           ++LG  ++
Sbjct: 459 YLLGQMII 466


>UniRef50_A7I3J6 Anaerobic C4-dicarboxylate transporter DcuA n=8 Tax=Bacteria
           RepID=A7I3J6_CAMHC
          Length = 497

 Score =  456 bits (1174), Expect = e-127,   Method: Composition-based stats.
 Identities = 255/494 (51%), Positives = 329/494 (66%), Gaps = 61/494 (12%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAAIGVKPGNIPFDVISIIMAVIAAI 60
           ML++E+I++L AIFLG +LGG+ IG+AGGLGV++L  +G+K G+IP+DVI II +VI+AI
Sbjct: 4   MLILEIIVLLGAIFLGVKLGGMAIGYAGGLGVVILTMLGLKAGSIPWDVILIIASVISAI 63

Query: 61  SAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAK 120
           +AMQVAGGLDYLV   EKLLR+NPKY+  LAP VTY LTIFAGTG+ + + +PVIAEVAK
Sbjct: 64  AAMQVAGGLDYLVQLAEKLLRKNPKYVNFLAPTVTYLLTIFAGTGHTAFSMIPVIAEVAK 123

Query: 121 EQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVME--GHGISYLHLLSVVIPSTLLA 178
            Q +KP  PLS AVVS+QIAITASP+SAAV++M+  M   G GISY  LL++ IP+T L 
Sbjct: 124 GQNIKPSVPLSIAVVSSQIAITASPVSAAVIFMAGDMALGGLGISYPILLAIWIPTTFLG 183

Query: 179 VLVMSFLVTMLFNSKLSDDPIYRKRLEEGLVELRGE--KQIEIKSGAKTSVWLFLLGVVG 236
            ++ + ++ + +N KL  DP+Y+ RL +GLV    +  K  E+  GAKTSV +F +G++ 
Sbjct: 184 CMITALIMNLFWNLKLDSDPVYKDRLAKGLVAEPQKEGKYKELPKGAKTSVLIFFIGIIA 243

Query: 237 VVIYAIINSPSMGLVEKP------------------------------------------ 254
           VV YA   S ++ LV+                                            
Sbjct: 244 VVFYATAISKNVALVKPSYVTGYEKVYQSKDAAKFDEIIAANPNIKISTDKDTGVKYVED 303

Query: 255 --------LMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSACICILGVAWL 306
                    +    AI+  ML +  L  +ICK+D D I   STFK+GM+ACIC+LGVAWL
Sbjct: 304 KSKPKKSLTLARDGAIMSFMLIIGALIVMICKIDVDKIPVQSTFKSGMTACICVLGVAWL 363

Query: 307 GDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMP-MALALNV-- 363
           GDTFVSN+   IKD AG +++ +P LL+V  FFAS LLYSQAATAKAL+P + +AL +  
Sbjct: 364 GDTFVSNHTQEIKDFAGNLVKQYPALLSVALFFASMLLYSQAATAKALIPTVIVALGLSA 423

Query: 364 ----SPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLGVA 419
                    VASFAAVS LF+LPTYPTL+ AVQMDDTGTTRIGK+VFNHPFFIPG L +A
Sbjct: 424 TNNGDAYILVASFAAVSALFVLPTYPTLLGAVQMDDTGTTRIGKYVFNHPFFIPGVLAIA 483

Query: 420 LAVCFGFVLGSFML 433
            +V FGFVL   ML
Sbjct: 484 FSVTFGFVLAPMML 497


>UniRef50_C9R1M8 Anaerobic C4-dicarboxylate membrane transporter n=9
           Tax=Proteobacteria RepID=C9R1M8_AGGAD
          Length = 440

 Score =  456 bits (1174), Expect = e-127,   Method: Composition-based stats.
 Identities = 187/439 (42%), Positives = 269/439 (61%), Gaps = 8/439 (1%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVL-AAIGVKPGNIPFDVISIIMAVIAA 59
           M + +  IVLL I +GAR+GGIG+G  GGLG+ +L    G+KP  +P DV+ +IMAV+AA
Sbjct: 4   MFLFQFAIVLLCILIGARVGGIGLGVFGGLGLTILSFGFGLKPAGLPIDVMFMIMAVVAA 63

Query: 60  ISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVA 119
            +AMQ AGGLDY++     +LRRNPK IT +AP VT+  T+ AGTG+++ + LPVIAEV+
Sbjct: 64  AAAMQAAGGLDYMIKIATNILRRNPKDITFMAPAVTWTFTLLAGTGHVAYSVLPVIAEVS 123

Query: 120 KEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAV 179
           ++ G++P RPLS AV+++Q AI ASPI+AAVV + + +E  GI    +L V IPST++ +
Sbjct: 124 RQNGIRPERPLSMAVIASQFAIVASPIAAAVVAVVAYLEPQGIHLGDVLIVTIPSTIIGL 183

Query: 180 LVMSFLVTMLFNSKLSDDPIYRKRLEEGLV-----ELRGEKQIEIKSGAKTSVWLFLLGV 234
            +    V  +   +L DDP Y++RL +             K++EI   AK SV LFL G 
Sbjct: 184 FLACIFVNKM-GKELKDDPEYQRRLNDPKYAEAFNSTTSSKELEISKTAKISVSLFLFGA 242

Query: 235 VGVVIYAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGM 294
           + VV+   + S       KP M   +AI IIML++  L  + CK D   I   S F AGM
Sbjct: 243 LLVVLMGAMPSLRPVFDGKP-MGMAHAIEIIMLTIGALIILTCKPDGTEITKGSVFHAGM 301

Query: 295 SACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKAL 354
            A I I G+AWLGDT +  +++ +K     +++  PW  A+  F  S L+ SQ AT   L
Sbjct: 302 RAVIAIFGIAWLGDTLMQAHLEEVKGMVRGLVETAPWTFAIALFILSVLVNSQGATVATL 361

Query: 355 MPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPG 414
            P+ +AL + P   V  F AV+G F +P Y  ++A++  D TGTTRIGK++FNH F +PG
Sbjct: 362 FPLGIALGIPPAVLVGVFVAVNGYFFIPNYGPIIASIDFDTTGTTRIGKYIFNHSFMLPG 421

Query: 415 TLGVALAVCFGFVLGSFML 433
            L +A ++  G +  +  L
Sbjct: 422 LLSMAFSLALGLLFANIFL 440


>UniRef50_B4CX44 Anaerobic c4-dicarboxylate antiporter, Dcu family n=1
           Tax=Chthoniobacter flavus Ellin428 RepID=B4CX44_9BACT
          Length = 444

 Score =  451 bits (1162), Expect = e-125,   Method: Composition-based stats.
 Identities = 183/439 (41%), Positives = 271/439 (61%), Gaps = 9/439 (2%)

Query: 2   LVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLA-AIGVKPGNIPFDVISIIMAVIAAI 60
           L++E +++L A+ +GAR GG+G+G  G +G+LVL    G+ P +IP +V+ I++ VI A 
Sbjct: 5   LILEFLVILGALAMGARAGGVGLGLWGAVGLLVLVLGFGIAPASIPGEVLLIVLTVIMAA 64

Query: 61  SAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAK 120
           SAM+VAGG+D+LV   EK++R NPK +TI+AP+VTY  T  AGTG+I    LPVI EVA 
Sbjct: 65  SAMEVAGGIDFLVRVAEKIIRSNPKQVTIVAPLVTYGFTFAAGTGHIVYPLLPVIYEVAY 124

Query: 121 EQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAVL 180
           E G++P RP++ A +++Q AITASP+SAA   M  ++  H I  + +L + +PSTLLAVL
Sbjct: 125 ENGIRPERPMAVATIASQQAITASPVSAATAAMIGLLAAHHIGLVQILIICVPSTLLAVL 184

Query: 181 VMSFLVTMLFNSKLSDDPIYRKRLEEGLVELRGEKQIEIKS----GAKTSVWLFLLGVVG 236
           + +F V +    +L DDP Y++ L  G +   G+           GAK+S ++FL GV  
Sbjct: 185 ISAF-VQLHVGKELKDDPEYQRLLASGKLHPPGKTSGATPPPLKNGAKSSAFIFLAGVSL 243

Query: 237 VVIYAIINSPS---MGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAG 293
           VV+  I            +  +++   AI I+ML+VA +   + K   + +    T ++G
Sbjct: 244 VVLAGIFPVLRTVDASSAKPTVLSMPIAIAIVMLAVAAVILTVTKAPVEEVPKCKTCQSG 303

Query: 294 MSACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKA 353
           ++A I ILG+AWLGDTF++ N + I      + +  PW  A+  F AS LLYSQAAT +A
Sbjct: 304 VTAIIGILGLAWLGDTFINANRETIIGGLSSMAKAAPWTFAIGLFLASMLLYSQAATTRA 363

Query: 354 LMPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIP 413
           LMP+ L+L +     +  F AV+G F +P Y TL+AA+Q D T TT IGK++ NH F +P
Sbjct: 364 LMPLGLSLGIPAPFLIGMFPAVNGYFFIPNYGTLIAAMQFDRTHTTHIGKYLLNHSFMLP 423

Query: 414 GTLGVALAVCFGFVLGSFM 432
           G +     V  G ++ SFM
Sbjct: 424 GLVSTIGGVSIGLLIASFM 442


>UniRef50_P44855 Anaerobic C4-dicarboxylate transporter dcuB n=162 Tax=Bacteria
           RepID=DCUB_HAEIN
          Length = 440

 Score =  451 bits (1161), Expect = e-125,   Method: Composition-based stats.
 Identities = 185/439 (42%), Positives = 266/439 (60%), Gaps = 8/439 (1%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVL-AAIGVKPGNIPFDVISIIMAVIAA 59
           M +++  IVLL IF+GAR+GGIG+G  GGLG+ +L    G+KP  +P DV+ +IMAV+AA
Sbjct: 4   MFLLQFAIVLLCIFVGARVGGIGLGVFGGLGLAILSFGFGLKPAGLPIDVMFMIMAVVAA 63

Query: 60  ISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVA 119
            +AMQ AGGLDY++    K+LRRNPK+IT +AP VT+  T+ AGTG+++ + LPVIAEV+
Sbjct: 64  AAAMQAAGGLDYMIKIATKILRRNPKHITFIAPAVTWLFTLLAGTGHVAYSVLPVIAEVS 123

Query: 120 KEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAV 179
           ++ G++P RP+S AV+++Q AI ASPI+AAVV + + +E  GI    +L V IPST+L +
Sbjct: 124 RQNGIRPERPMSMAVIASQFAIVASPIAAAVVAVVAYLEPQGIHLGDVLMVTIPSTILGL 183

Query: 180 LVMSFLVTMLFNSKLSDDPIYRKRLEEGLV-----ELRGEKQIEIKSGAKTSVWLFLLGV 234
            +    V  +   +L DDP Y++RL +             K++E+   AK SV LFL G 
Sbjct: 184 FLACLFVNKM-GKELKDDPEYQRRLNDPKYADIFASTTSVKEVEVSKTAKISVSLFLFGA 242

Query: 235 VGVVIYAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGM 294
           + VV+     S       KP M   + I IIMLS+  L  + CK D   I   S F AGM
Sbjct: 243 LLVVLMGAAPSIRPVFDGKP-MGMAHTIEIIMLSIGALIILTCKPDGTAITKGSVFHAGM 301

Query: 295 SACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKAL 354
            A I I G+AWLGDT +  +I  +K+    +++  PW  A   F  S L+ SQ AT   L
Sbjct: 302 RAVIAIFGIAWLGDTLMQAHITEVKEMVKGLVETAPWAFAFALFVLSVLVNSQGATVATL 361

Query: 355 MPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPG 414
            P+ +AL +     +  F AV+G F +P Y  ++A++  D TGTT+IGK++ NH F +PG
Sbjct: 362 FPLGIALGIPAPVLIGVFVAVNGYFFIPNYGPIIASLDFDTTGTTKIGKYILNHSFMLPG 421

Query: 415 TLGVALAVCFGFVLGSFML 433
            L +   +  G  L   +L
Sbjct: 422 LLSMFFCLLIGLGLSHVIL 440


>UniRef50_C8N6Y6 Anaerobic C4-dicarboxylate transporter DcuB n=1 Tax=Cardiobacterium
           hominis ATCC 15826 RepID=C8N6Y6_9GAMM
          Length = 479

 Score =  441 bits (1135), Expect = e-122,   Method: Composition-based stats.
 Identities = 174/457 (38%), Positives = 267/457 (58%), Gaps = 26/457 (5%)

Query: 2   LVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAA-IGVKPGNIPFDVISIIMAVIAAI 60
            +++  IVLL I LGAR+GGIG+G  GGLG+ +L    G++P + P DV+ +IMAV++A 
Sbjct: 24  FLIQFAIVLLCILLGARVGGIGLGVFGGLGLAILTFGFGLQPTSPPIDVMLMIMAVVSAA 83

Query: 61  SAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAK 120
           +AM+ +GGLD ++    ++LR+NPKYIT +AP VTY  TIFAGTG+++ + LPVIAEV++
Sbjct: 84  AAMEASGGLDLMIRVATRILRKNPKYITFMAPAVTYIFTIFAGTGHVAYSVLPVIAEVSR 143

Query: 121 EQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAVL 180
             G++P RPLS AV+++Q +I ASPI+AAV   +S +  + IS   +L V IPST L + 
Sbjct: 144 RSGIRPERPLSMAVIASQFSIVASPIAAAVTSAASYLTPYHISIPQILMVTIPSTTLGIA 203

Query: 181 VMSFLVTMLFNSKLSDDPIYRKRLEEGLVEL--------RGEKQIEIKSGAKTSVWLFLL 232
           +    V  +   +L DDP Y++RL++ + +          G + +  +  A+TS+ +F+ 
Sbjct: 204 IACVFVNKM-GKELKDDPEYQRRLKDPVYQEIYAAQESSSGTETVINEKSARTSLKIFIS 262

Query: 233 GVVGVVIYAIINSP------------SMGLVEKP----LMNTTNAILIIMLSVATLTTVI 276
             + VVI   ++                   +      L+N  + I I+ML+ A    + 
Sbjct: 263 AAILVVILGSLDKLAKYLPAELMAHLRPSFPDAKGDMKLLNMPHVIEIVMLTAAAFIIMF 322

Query: 277 CKVDTDNILNSSTFKAGMSACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVI 336
           CK D   I   S F AGM A I I G+AWLGDT  + ++D +K     +++  PW  A  
Sbjct: 323 CKPDGTAITRGSVFHAGMRAVIAIFGIAWLGDTLFNAHLDELKTLVSGLVETAPWTFAFA 382

Query: 337 FFFASALLYSQAATAKALMPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDT 396
            F  S L+ SQ AT   L P+ ++L + P   V +F AV+G F +P Y  ++A++  D T
Sbjct: 383 LFAFSVLVNSQGATVATLFPLGVSLGIPPEIMVGTFVAVNGYFFIPNYGPIIASIDFDTT 442

Query: 397 GTTRIGKFVFNHPFFIPGTLGVALAVCFGFVLGSFML 433
           GTTRIG+++ NH F IPG L +A ++  G      +L
Sbjct: 443 GTTRIGRYILNHSFMIPGLLSMAFSLVLGLAFAKMLL 479


>UniRef50_C6CN04 Anaerobic c4-dicarboxylate antiporter, Dcu family n=22 Tax=Bacteria
           RepID=C6CN04_DICZE
          Length = 453

 Score =  440 bits (1132), Expect = e-122,   Method: Composition-based stats.
 Identities = 153/442 (34%), Positives = 260/442 (58%), Gaps = 14/442 (3%)

Query: 2   LVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAA-IGVKPGNIPFDVISIIMAVIAAI 60
            +++L+IVL+ +F GAR GGI +G  GG+G+++L     ++PG  P DV+ +I++V+AA 
Sbjct: 10  FIIQLVIVLICLFYGARKGGIALGLLGGIGLVILVFIFKLEPGKPPVDVMLVIISVVAAS 69

Query: 61  SAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAK 120
           + +Q +GGLD ++   EK+LRRNPKY++I+AP VT  LT+  GTG++    LP+I +VA 
Sbjct: 70  ATLQASGGLDVMLQVAEKMLRRNPKYVSIIAPFVTCILTMLCGTGHVVYTILPIIYDVAI 129

Query: 121 EQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVM-----EGHGISYLHLLSVVIPST 175
           +  ++P RP++ + + AQ+ I ASP+S AVV + +++      G  + +L LL++ IPST
Sbjct: 130 KNNIRPERPMAASSIGAQMGIIASPVSVAVVSLVAMLGKFTFHGKHLEFLDLLAITIPST 189

Query: 176 LLAVLVMSFLVTMLFNSKLSDDPIYRK--RLEEGLVELRGEK----QIEIKSGAKTSVWL 229
           LL +L +  + +      L  DP ++K   + E    + G+       ++      ++W+
Sbjct: 190 LLGILAIG-IFSWFRGKDLDKDPDFQKFISVPENREYVYGDTATLLDRKLPRSNWVAMWI 248

Query: 230 FLLGVVGVVIYAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSST 289
           FL  +  V +   + S          ++    I + ML    +  +  K +  +I  +  
Sbjct: 249 FLATIAAVALLGAVESLRPTF-GGKPLSMVLVIQMFMLLSGAIIIIATKTNPGSISKNEV 307

Query: 290 FKAGMSACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAA 349
           F++GM A + + G+AW+ +T    ++  IK+T G +++ +PW  A++    S  + SQAA
Sbjct: 308 FRSGMIAIVAVYGIAWMAETMFGAHLAEIKETLGTLVKDYPWAYALVLLLVSKFVNSQAA 367

Query: 350 TAKALMPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHP 409
              A++P+ALA+ V P   VAS  A  G +ILPTYP+ +AA+Q D +GTT IG+FV NH 
Sbjct: 368 ALAAIVPVALAIGVDPAYIVASAPACYGYYILPTYPSDLAAIQFDRSGTTHIGRFVINHS 427

Query: 410 FFIPGTLGVALAVCFGFVLGSF 431
           F +PG +GV+ +  FG+V  + 
Sbjct: 428 FILPGLIGVSTSCVFGWVFAAM 449


>UniRef50_Q5HVA4 Anaerobic C4-dicarboxylate membrane transporter DcuB n=25
           Tax=Proteobacteria RepID=Q5HVA4_CAMJR
          Length = 474

 Score =  438 bits (1128), Expect = e-121,   Method: Composition-based stats.
 Identities = 151/457 (33%), Positives = 257/457 (56%), Gaps = 30/457 (6%)

Query: 2   LVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAA-IGVKPGNIPFDVISIIMAVIAAI 60
             +++IIVL+ +F GA+ GGI +G  GG+G+L+L     +KPG    DV+  I+AV+ A 
Sbjct: 13  FAIQIIIVLICLFYGAKKGGIALGLLGGIGILMLVFTFHIKPGKPAIDVMLTILAVVVAS 72

Query: 61  SAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAK 120
           + +Q +GGLD ++   E++LRRNPK++TILAP VT FLTI  GTG++    +P+I ++A 
Sbjct: 73  ATLQASGGLDVMLQIAERILRRNPKFLTILAPFVTCFLTILCGTGHVVYTIMPIIYDIAI 132

Query: 121 EQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVM--EGHGI----SYLHLLSVVIPS 174
           + G++P RP++ A +S+Q+ I ASP+S AVV +++++    H +     Y++LL + IPS
Sbjct: 133 KNGIRPERPMAAASISSQMGIIASPVSVAVVSLTALLLNANHKLAGFDGYINLLQITIPS 192

Query: 175 TLLAVLVMSFLVTMLFNSKLSDDPIYRKRLEEGLVELR------GEKQIEIKSGAKTSVW 228
           TL  VL +  + +      L  D +++++L++   +            +++      ++W
Sbjct: 193 TLFGVLCVG-IFSWFRGKDLDKDEVFQEKLKDPEFKKYVYGDSKTLLGVKLPKSNWVAMW 251

Query: 229 LFLLGVVGVVIYAIINSPSMGL----------------VEKPLMNTTNAILIIMLSVATL 272
           +FL  +  V +  + +                       +  +++  + I + ML   +L
Sbjct: 252 IFLGAIALVALLGVFDFLRPNWGQVVKNGIPQVDALGNPKMDVLSMVSVIQMFMLLAGSL 311

Query: 273 TTVICKVDTDNILNSSTFKAGMSACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWL 332
             +  K D   I ++  FK+GM A + + G++W+ DT  + +   +K   G++++ HPW 
Sbjct: 312 IIIFTKTDAKKIGSNEIFKSGMIALVAVFGISWMADTMFAVHTPMMKAALGDIVKEHPWT 371

Query: 333 LAVIFFFASALLYSQAATAKALMPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQ 392
            AV+    S  + SQAA   A +P+AL + V P   VA  AA  G +ILPTYP+ +A +Q
Sbjct: 372 YAVMLLLISKFVNSQAAAISAFVPLALGIGVEPGAIVAFAAACYGYYILPTYPSDLATIQ 431

Query: 393 MDDTGTTRIGKFVFNHPFFIPGTLGVALAVCFGFVLG 429
            D +GTT IGKFV NH F +PG +GV  +   G+ + 
Sbjct: 432 FDRSGTTHIGKFVINHSFILPGLIGVITSCIAGYFIA 468


>UniRef50_Q5E4K5 Anaerobic C4-dicarboxylate transporter n=16 Tax=Gammaproteobacteria
           RepID=Q5E4K5_VIBF1
          Length = 433

 Score =  433 bits (1113), Expect = e-120,   Method: Composition-based stats.
 Identities = 186/433 (42%), Positives = 289/433 (66%), Gaps = 3/433 (0%)

Query: 2   LVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLA-AIGVKPGNIPFDVISIIMAVIAAI 60
           +++E+ +VL+ I+ G ++GG+G+G AGG G+ VL   +G++P     DVI IIM+V+ A 
Sbjct: 3   VIIEISVVLICIYWGLKMGGLGVGLAGGFGLAVLTLGLGLEPSAPAIDVILIIMSVVTAA 62

Query: 61  SAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAK 120
           S MQ AGG+++LVH    L+RR+PKYI ILAPI+T+ +TI AGTG    +TLPVI+EVAK
Sbjct: 63  STMQAAGGMEWLVHHAGNLMRRHPKYINILAPIITWCMTIMAGTGYTVFSTLPVISEVAK 122

Query: 121 EQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAVL 180
           E G +P RPLS AVV++Q+AI+ SPISAA+  M S+ME  G+S+L ++++ +P++ +A +
Sbjct: 123 EIGERPSRPLSAAVVASQVAISGSPISAAMAAMISIMEPAGVSFLQIMAICLPASFIAAM 182

Query: 181 VMSFLVTMLFNSKLSDDPIYRKRLEEGLVELRGEKQIEIKSGAKTSVWLFLLGVVGVVIY 240
           V +F+ +     +L DD +Y++  +E    +      +I   AK SV+LF L    +V+Y
Sbjct: 183 VAAFIASRQ-GCELKDDVVYQQIQKENKQHVTSMT-KDIDPKAKYSVFLFALATCAIVLY 240

Query: 241 AIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSACICI 300
           A I S         +M T + I++ M + A L   +C +  D I+ ++TF++GMS+   I
Sbjct: 241 AAIPSLRPAFPSGDIMTTRDIIIVSMFAAACLMVPMCNIHPDRIIKTTTFRSGMSSVAVI 300

Query: 301 LGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPMALA 360
           LG+  +G T V+ ++  IK+ AG ++  +P LL+++ F    LL SQ AT   ++P+AL+
Sbjct: 301 LGIVTMGSTVVNAHLPEIKEFAGSLLHSYPMLLSLVLFGTCTLLMSQGATTPLIVPLALS 360

Query: 361 LNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLGVAL 420
           LNV     +ASF AV+G+F+LPTYPT +AA++ D TG+TR+GK +F+HPF +PG  GV +
Sbjct: 361 LNVPHWAILASFVAVTGVFVLPTYPTSLAAIEFDSTGSTRMGKNIFDHPFMLPGLTGVIV 420

Query: 421 AVCFGFVLGSFML 433
           A+ FGF+L   +L
Sbjct: 421 AIGFGFLLAPAVL 433


>UniRef50_Q9ZLC0 Anaerobic C4-dicarboxylate transporter dcuA n=226 Tax=Bacteria
           RepID=DCUA_HELPJ
          Length = 443

 Score =  432 bits (1112), Expect = e-119,   Method: Composition-based stats.
 Identities = 236/440 (53%), Positives = 314/440 (71%), Gaps = 10/440 (2%)

Query: 3   VVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLA-AIGVKPGNIPFDVISIIMAVIAAIS 61
             ++I++L ++FLGARLGG+G+G+AGGLGVL+L   +G+ PG IPFDVI IIMAVI+AIS
Sbjct: 5   FFQIIVLLFSLFLGARLGGLGVGYAGGLGVLILCLFLGLNPGKIPFDVILIIMAVISAIS 64

Query: 62  AMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAKE 121
           AMQ AGGLDYLV   EK+LR++PK I  LAP V YFLTI AGTG+   + +PVI EV++ 
Sbjct: 65  AMQKAGGLDYLVQIAEKILRKHPKQINYLAPSVAYFLTILAGTGHTVFSLIPVIVEVSQS 124

Query: 122 QGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAVLV 181
           Q +KP  PLS AVVS+Q+AITASP+SAAVV+MS ++E  G  YL LL V IP+T LA ++
Sbjct: 125 QNIKPKAPLSLAVVSSQVAITASPVSAAVVFMSGILEPLGADYLTLLMVWIPTTFLACML 184

Query: 182 MSFLVTMLFNSKLSDDPIYRKRLEEGLVELRG-EKQIEIKSGAKTSVWLFLLGVVGVVIY 240
            +F++    + KL  DP Y +RL+ G +     +K+ E    AK S+W+F+ GVV +V Y
Sbjct: 185 TAFVMGFT-DLKLDSDPNYLERLKAGKISPPMMKKEKETSKSAKLSLWIFIGGVVAIVFY 243

Query: 241 AIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSACICI 300
           A   S ++ L+   ++    AI+  MLSVATL  + CK++ + I +SS FK+GM AC+C+
Sbjct: 244 ASAISKNIALISPVILGRDYAIVSFMLSVATLIAIFCKINANEIAHSSVFKSGMQACVCV 303

Query: 301 LGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPMAL- 359
           LGVAWLGDTFVSN+ID IK  A  +I  +P+LLAV  F AS LLYSQAAT+KAL+P  + 
Sbjct: 304 LGVAWLGDTFVSNHIDEIKRYASFLIADYPFLLAVALFLASMLLYSQAATSKALIPSVIT 363

Query: 360 ALNVSP------LTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIP 413
           AL +S          VASFA+VS LF+LPTYPTL+ A+ MD TGTT++G++VF+H F IP
Sbjct: 364 ALGISANHTEHLYIIVASFASVSALFVLPTYPTLLGAIAMDHTGTTKMGRYVFDHAFLIP 423

Query: 414 GTLGVALAVCFGFVLGSFML 433
           G L V L+V  GFV+   +L
Sbjct: 424 GVLVVFLSVALGFVVAPLVL 443


>UniRef50_P0ABP1 Anaerobic C4-dicarboxylate transporter dcuB n=130 Tax=Bacteria
           RepID=DCUB_ECO57
          Length = 446

 Score =  430 bits (1105), Expect = e-119,   Method: Composition-based stats.
 Identities = 136/407 (33%), Positives = 233/407 (57%), Gaps = 13/407 (3%)

Query: 36  AAIGVKPGNIPFDVISIIMAVIAAISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVT 95
               ++PG  P DV+ +I+AV+AA + +Q +GGLD ++   EKLLRRNPKY++I+AP VT
Sbjct: 38  FVFHLQPGKPPVDVMLVIIAVVAASATLQASGGLDVMLQIAEKLLRRNPKYVSIVAPFVT 97

Query: 96  YFLTIFAGTGNISLATLPVIAEVAKEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSS 155
             LTI  GTG++    LP+I +VA +  ++P RP++ + + AQ+ I ASP+S AVV + +
Sbjct: 98  CTLTILCGTGHVVYTILPIIYDVAIKNNIRPERPMAASSIGAQMGIIASPVSVAVVSLVA 157

Query: 156 VM-----EGHGISYLHLLSVVIPSTLLAVLVMSFLVTMLFNSKLSDDPIYRK--RLEEGL 208
           ++     +G  + +L LL++ IPSTL+ +L +  + +      L  D  ++K   + E  
Sbjct: 158 MLGNVTFDGRHLEFLDLLAITIPSTLIGILAIG-IFSWFRGKDLDKDEEFQKFISVPENR 216

Query: 209 VELRGEK----QIEIKSGAKTSVWLFLLGVVGVVIYAIINSPSMGLVEKPLMNTTNAILI 264
             + G+       ++      ++W+FL  +  V +    +           ++    I +
Sbjct: 217 EYVYGDTATLLDKKLPKSNWLAMWIFLGAIAVVALLGADSDLRPSF-GGKPLSMVLVIQM 275

Query: 265 IMLSVATLTTVICKVDTDNILNSSTFKAGMSACICILGVAWLGDTFVSNNIDWIKDTAGE 324
            ML    L  ++ K +  +I  +  F++GM A + + G+AW+ +T    ++  I+   GE
Sbjct: 276 FMLLTGALIIILTKTNPASISKNEVFRSGMIAIVAVYGIAWMAETMFGAHMSEIQGVLGE 335

Query: 325 VIQGHPWLLAVIFFFASALLYSQAATAKALMPMALALNVSPLTAVASFAAVSGLFILPTY 384
           +++ +PW  A++    S  + SQAA   A++P+ALA+ V P   VAS  A  G +ILPTY
Sbjct: 336 MVKEYPWAYAIVLLLVSKFVNSQAAALAAIVPVALAIGVDPAYIVASAPACYGYYILPTY 395

Query: 385 PTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLGVALAVCFGFVLGSF 431
           P+ +AA+Q D +GTT IG+FV NH F +PG +GV+++  FG++  + 
Sbjct: 396 PSDLAAIQFDRSGTTHIGRFVINHSFILPGLIGVSVSCVFGWIFAAM 442


>UniRef50_B4UMD4 Anaerobic c4-dicarboxylate antiporter, Dcu family n=20
           Tax=Proteobacteria RepID=B4UMD4_ANASK
          Length = 447

 Score =  428 bits (1101), Expect = e-118,   Method: Composition-based stats.
 Identities = 163/446 (36%), Positives = 236/446 (52%), Gaps = 14/446 (3%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAA-IGVKPGNIPFDVISIIMAVIAA 59
           M  ++  +VL AI LG R GG+ +G  GGLGV VL       P   P  V+ II+AV+  
Sbjct: 3   MFWIQFALVLGAILLGIRRGGVALGMIGGLGVAVLVFLFRAAPSEPPIAVMLIILAVVTT 62

Query: 60  ISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVA 119
            + +QVAGGLDYLV   EKLLR +PKY+TILAP  T+FLT+  GTG+   A LPVIA+VA
Sbjct: 63  SATLQVAGGLDYLVQLAEKLLRAHPKYVTILAPFCTFFLTMAVGTGHAVYALLPVIADVA 122

Query: 120 KEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSV--MEGHGISYLHLLSVVIPSTLL 177
            +   +P RP++ + V++Q+ ITASP++AAV    +     G  +S   +L + IP+ ++
Sbjct: 123 LKTKTRPERPMAISSVASQMGITASPVAAAVTTFLAFSAKAGQPLSLYDILKITIPAGVV 182

Query: 178 AVLVMSFLVTMLFNSKLSDDPIYRKRLEEGLVELRGE-----KQIEIKSGAKTSVWLFLL 232
            VL  + L +M     L  DP + K+LE+       +        ++   A+ SV LF  
Sbjct: 183 GVLAAA-LWSMNRGRDLYSDPEFLKKLEDPEFRKSLDVSVTTLDKQLPRAARLSVLLFFT 241

Query: 233 GVVGVVIYAIINS-----PSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNS 287
           GV  +V+ A+            +     +  T  + I+ML+         KV    +  S
Sbjct: 242 GVATIVVLALDQDFLHLGLIPLVNGGKPVAMTTVVQIVMLAFGAFILFTAKVKAAEVARS 301

Query: 288 STFKAGMSACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQ 347
           S F AGM A + I G+AW+ DTFV+ N  ++ +    ++Q  PW  AV  F  SA + SQ
Sbjct: 302 SVFTAGMIAVVSIFGIAWMSDTFVTANKPFLIEKIQAMVQVAPWTFAVAMFCVSAFVKSQ 361

Query: 348 AATAKALMPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFN 407
           AAT   ++P  LAL +     +    A    F    YP+ +AA+ MD TGTT IGK++ N
Sbjct: 362 AATLTIMLPFGLALGLPATLLLGLMPASYAYFFFCFYPSDLAAINMDRTGTTHIGKYLLN 421

Query: 408 HPFFIPGTLGVALAVCFGFVLGSFML 433
           H F IPG +GV  +    + L     
Sbjct: 422 HSFMIPGFIGVGTSTVVAYALSRLAF 447


>UniRef50_Q7NRZ2 Anaerobic C4-dicarboxylate membrane transporter protein n=1
           Tax=Chromobacterium violaceum RepID=Q7NRZ2_CHRVO
          Length = 436

 Score =  426 bits (1097), Expect = e-118,   Method: Composition-based stats.
 Identities = 174/433 (40%), Positives = 274/433 (63%), Gaps = 6/433 (1%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAA-IGVKPGNIPFDVISIIMAVIAA 59
           M+ ++L++VL  IFLG R+GGIG+G  GG G+ +L    G+KPG+ P DVI II++VI A
Sbjct: 1   MVYLQLVVVLGLIFLGVRMGGIGLGVTGGAGLFILTFVFGLKPGHAPIDVILIIISVITA 60

Query: 60  ISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVA 119
            +A+Q A GLDY+V    +LLRRNP++I +LAP+V +  T  AGTG I+LA +P++ EVA
Sbjct: 61  SAALQSARGLDYMVGVAARLLRRNPRHIVLLAPLVGWLSTFLAGTGFIALALMPIVVEVA 120

Query: 120 KEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAV 179
           ++ G++P RPL+   V++Q AI A P+SAA V +++V+  HG++   ++ + IP+TLL  
Sbjct: 121 EKTGIRPERPLAGLTVASQNAIVACPVSAATVALATVLAPHGVALTDIIMISIPATLLGA 180

Query: 180 LVMSFLVTMLFNSKLSDDPIYRKRLEEGLV-ELRGEKQIEIKSGAKTSVWLFLLGVVGVV 238
           L     V + +  +L+DDP+YR+RL +G +   + + +  +   A  SV+ FLL V  +V
Sbjct: 181 L-AGGAVMLRYGCELADDPVYRQRLADGGIRRPQTDAEEALPRTAAWSVYGFLLTVALIV 239

Query: 239 IYAIINSPSMGLVEKPLMN---TTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMS 295
           + A +            M      + I + ML  + L  ++CK D   +++ S F++G  
Sbjct: 240 LLAAMPQLRPAWPGAKGMEPVAMVDVIQMCMLGYSALAVLVCKADLQGMVSGSMFRSGAV 299

Query: 296 ACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALM 355
           A + ILG AW+ DTF+  N+   K     +I+  PWL A   F  + +L+SQ AT K +M
Sbjct: 300 AAVTILGAAWMSDTFIQANLPLFKHNIVSIIESAPWLFAFAVFTMAVILFSQGATTKVMM 359

Query: 356 PMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGT 415
           P+ ++L ++    +A + AV G+++LP+YP+L+AAV+MD TGTTRIG++VFNH F +PG 
Sbjct: 360 PLGVSLGIASPVLIAIYPAVVGVYVLPSYPSLIAAVEMDYTGTTRIGRWVFNHSFILPGL 419

Query: 416 LGVALAVCFGFVL 428
              A+++  GF L
Sbjct: 420 ASTAVSIAAGFAL 432


>UniRef50_B4TYZ8 Anaerobic C4-dicarboxylate transporter DcuA n=30 Tax=Bacteria
           RepID=B4TYZ8_SALSV
          Length = 439

 Score =  425 bits (1094), Expect = e-117,   Method: Composition-based stats.
 Identities = 180/439 (41%), Positives = 276/439 (62%), Gaps = 7/439 (1%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAA-IGVKPGNIPFDVISIIMAVIAA 59
           M   EL  +L+A+ +GAR+GG+ +G  GGLGV V+    G+ P   P DVI II++V+ A
Sbjct: 1   MFWTELCFILVALMIGARIGGVFLGMVGGLGVGVMVFIFGLTPSTPPIDVILIILSVVLA 60

Query: 60  ISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVA 119
            +++Q +GGLD LV   EK+LRR+P+YIT+LAP + Y  T  +GTG++  + LPVI+EVA
Sbjct: 61  AASLQASGGLDLLVKLAEKILRRHPRYITLLAPFICYIFTFMSGTGHVVYSLLPVISEVA 120

Query: 120 KEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAV 179
           ++ G++P RPLS +V+++Q AITASPISAA+  M  +M   G+S   ++ + +P+TL+ V
Sbjct: 121 RDSGIRPERPLSISVIASQQAITASPISAAMAAMIGLMAPLGVSISTIMMICVPATLIGV 180

Query: 180 LVMSFLVTMLFNSKLSDDPIYRKRLEEGLVEL--RGEKQIEIKSGAKTSVWLFLLGVVGV 237
             M  + T     +L DDP Y++RL EGL++   +  K   + S AK SV LFL   + +
Sbjct: 181 -AMGAIATFNKGKELKDDPEYQRRLAEGLIKPAQKESKNTVVTSRAKLSVALFLTSAIVI 239

Query: 238 VIYAIINSPSMGLV---EKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGM 294
           V+  +I +    +        ++ + AI I MLS A L  ++C+   D I++ + F+AG 
Sbjct: 240 VLLGLIPALRPMVETAKGLQPLSMSAAIQITMLSFACLIVLLCRPQVDQIISGTVFRAGA 299

Query: 295 SACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKAL 354
            A +C  G+AW+ +TFV+ +I  IK     ++Q H WL+A++ FF SA++ SQAAT   L
Sbjct: 300 LAIVCAFGLAWMSETFVNGHIALIKAEVQTLLQQHTWLIAIMMFFVSAMVSSQAATTLIL 359

Query: 355 MPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPG 414
           +P+ LAL +     + S+ AV+G F +P     +AA+  DDTGTTRIGK+V NH F  PG
Sbjct: 360 LPLGLALGLPAYALIGSWPAVNGYFFIPVAGQCLAALAFDDTGTTRIGKYVLNHSFMRPG 419

Query: 415 TLGVALAVCFGFVLGSFML 433
            + V ++V  G ++G  +L
Sbjct: 420 LVNVIVSVIVGLLIGKMVL 438


>UniRef50_D1P157 Anaerobic C4-dicarboxylate transporter DcuB n=2 Tax=Providencia
           RepID=D1P157_9ENTR
          Length = 443

 Score =  424 bits (1091), Expect = e-117,   Method: Composition-based stats.
 Identities = 200/434 (46%), Positives = 294/434 (67%), Gaps = 2/434 (0%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLA-AIGVKPGNIPFDVISIIMAVIAA 59
           M+ +E+I+VL AIF G R+GGIGIG  GGLG+ +L    G+  G+ P DVI IIM V+ A
Sbjct: 11  MVFLEIIVVLGAIFFGIRMGGIGIGLCGGLGLAILTIGFGLPIGSPPVDVILIIMTVVVA 70

Query: 60  ISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVA 119
            SA+Q AGG+DYLV      +R+NPKYI I+API T+ +TI AGTG I  + LPVIAE+A
Sbjct: 71  ASALQAAGGMDYLVRLAGTFMRKNPKYINIIAPITTWVMTIMAGTGFIVFSMLPVIAEIA 130

Query: 120 KEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAV 179
           K+ GV+P R L+ +VV++QIAI+ SPISAA+  M ++MEG+G++++ ++SV +P++ +A 
Sbjct: 131 KDSGVRPSRTLAGSVVASQIAISGSPISAAMAAMLTIMEGNGVTFITVMSVCLPASFVAA 190

Query: 180 LVMSFLVTMLFNSKLSDDPIYRKRLEEGLVELRGEKQIEIKSGAKTSVWLFLLGVVGVVI 239
           +V +F+ +     +L DD +Y  RL++GL+    EK+ E     K SV LF++  +G+VI
Sbjct: 191 MVAAFIASRQ-GCELEDDEVYLDRLQKGLIHKYEEKKGESTPKEKFSVILFIIATIGIVI 249

Query: 240 YAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSACIC 299
            A       G      M T + I+I MLS A L  V CK   ++I+ +STF++GMS+   
Sbjct: 250 LAAFPQLRPGFDIGKPMGTRDIIIICMLSAACLMVVFCKTSPNSIVLASTFRSGMSSLAV 309

Query: 300 ILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPMAL 359
           ILG+  LG TFV  ++  IK+ AG V+  +P LL+++ FF  ALLYSQ AT   ++P+A+
Sbjct: 310 ILGIVTLGTTFVDAHMVQIKEIAGNVLSSYPILLSLVLFFTCALLYSQGATTPLIIPLAI 369

Query: 360 ALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLGVA 419
           AL+V     +ASF AV+G+F+LPTYPT +AA++ D TG+TR+GK++ NHPF +PG  G+ 
Sbjct: 370 ALDVPTWAILASFVAVTGVFVLPTYPTSLAAMEFDSTGSTRVGKYILNHPFMLPGLGGII 429

Query: 420 LAVCFGFVLGSFML 433
             V FGF++   ++
Sbjct: 430 AGVAFGFIIAPMVV 443


>UniRef50_B6EGF2 Anaerobic c4-dicarboxylate transporter DcuB n=1 Tax=Aliivibrio
           salmonicida LFI1238 RepID=B6EGF2_ALISL
          Length = 444

 Score =  401 bits (1032), Expect = e-110,   Method: Composition-based stats.
 Identities = 153/442 (34%), Positives = 249/442 (56%), Gaps = 12/442 (2%)

Query: 2   LVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLA-AIGVKPGNIPFDVISIIMAVIAAI 60
             ++L +VL  I +G R GG+G+G AGGLGV +L    G++P + P  V+ II+AVIA  
Sbjct: 5   FWLQLAVVLGCIGIGGRFGGVGLGAAGGLGVCLLVLGFGLQPASPPVTVLLIIIAVIACT 64

Query: 61  SAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAK 120
           S +Q AGGLD+LV   EKLLR+ P  IT L P+++    IF GT  ++ A  PVIAEVA 
Sbjct: 65  SVLQGAGGLDFLVRIAEKLLRKKPSAITFLGPLISSMFVIFCGTSYVAFAVYPVIAEVAA 124

Query: 121 EQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAVL 180
           E  ++P RP+S AV+++ IAITASP+SAA   M + +  + +S+  +L+V +P+ L+  L
Sbjct: 125 EAKIRPERPMSMAVIASGIAITASPMSAATAGMIASLSLYDVSFFQILAVSMPAFLIGAL 184

Query: 181 VMSFLVTMLFNSKLSDDPIYRKRLEEGLVEL------RGEKQIEIKSGAKTSVWLFLLGV 234
                V      +L  DP +++R+  G  +L        E++ +  +G K SV +F LGV
Sbjct: 185 CGCAFVYK-RGLELEQDPEFQRRVASGEYQLIHEDVNSPEEEYKPSTGVKASVLVFGLGV 243

Query: 235 VGVVIYAIINSPSMGLV---EKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFK 291
             V+++    S         +  +++T   I ++ML+ A    V  KV +D   + S F+
Sbjct: 244 ATVILFGTFKSLLPSWDIDGKTVVLSTPMLIQMVMLASALFIIVFAKVPSDKFASGSVFR 303

Query: 292 AGMSACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATA 351
           +G+   + + G++W+  TF +    + + T   +++  P +  +I F  SA+++S +AT 
Sbjct: 304 SGLIGVVGVFGISWMTGTFFNAYQPFFETTFEGMVETAPMMFGLILFCFSAVIFSPSATV 363

Query: 352 KALMPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFF 411
            ALMP+  A+ + P   VA + A  G FI+P     +  +  D TGTTR+G +V NH + 
Sbjct: 364 SALMPLGAAMGIPPGLLVALYPATCGDFIVPGTGQ-IGCLSFDRTGTTRLGTYVINHSYI 422

Query: 412 IPGTLGVALAVCFGFVLGSFML 433
           +PG + V  +V  G+ +   + 
Sbjct: 423 LPGFVMVISSVTAGYFISKIVF 444


>UniRef50_C3JGC7 C4-dicarboxylate membrane transporter n=2 Tax=Rhodococcus
           erythropolis RepID=C3JGC7_RHOER
          Length = 443

 Score =  395 bits (1015), Expect = e-108,   Method: Composition-based stats.
 Identities = 138/438 (31%), Positives = 246/438 (56%), Gaps = 8/438 (1%)

Query: 2   LVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAA-IGVKPGNIPFDVISIIMAVIAAI 60
           +V+EL +VL AI +G R  G+ +G  GG GV VL    G   G+ P D + I+++V+ A 
Sbjct: 6   IVLELAVVLGAIVMGTRSSGVALGLWGGAGVAVLVFVFGEDVGSPPVDALLIVLSVVLAS 65

Query: 61  SAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAK 120
           S MQ AGG+D++V    KL+   PK IT++AP+V++  ++ AGT NI    LPVI +V+ 
Sbjct: 66  SMMQAAGGIDWMVTIAAKLIESRPKQITLIAPLVSFLFSVGAGTSNILYPLLPVIYDVSY 125

Query: 121 EQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVME--GHGISYLHLLSVVIPSTLLA 178
           + GV+P RPLS +VVS  +A+  SP+SAA+  M ++ +   +    + ++ +  P+ ++ 
Sbjct: 126 KNGVRPSRPLSLSVVSTGVALACSPVSAAMAAMVTLTDVPPYDFELIDIIKITFPAAVVG 185

Query: 179 VLVMSFLVTMLFNSKLSDDPIYRKRLEEGLVELRG---EKQIEIKSGAKTSVWLFLLGVV 235
           +++ S  V  L    L DDP  + +++ G +   G   + ++      + +  +FL GV+
Sbjct: 186 IVLSSIAVNRL-GKDLDDDPEIQAKMKSGELAGPGAASKTELVSTKTGRNAALIFLAGVL 244

Query: 236 GVVIYAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMS 295
            +VI+ +         +   M  T  I ++M  V TL  ++C+ +  ++ +S+ F+AGM 
Sbjct: 245 AIVIFGLFKGIRPEAADGTPMGMTPIIEMLMFVVGTLILLVCRPNVADVPSSTVFRAGMV 304

Query: 296 ACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALM 355
           + I + G+AWL DTF+S + + I  T G+ +   PW+ A+  F    L  SQ+   + ++
Sbjct: 305 SAIALFGLAWLTDTFISAHSELITSTVGDWVNAAPWIFALGVFLVCVLTTSQSTATRTIV 364

Query: 356 PMALALNVSPLTAVASFA-AVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPG 414
           P+ LA  ++P      +A A +G+++LPT  + +AA   D +G+T++G  + +H FF+P 
Sbjct: 365 PIGLAAGIAPGLVSGMWAGAFAGVYLLPTNGSQIAAANFDLSGSTKLGSKLVDHSFFLPT 424

Query: 415 TLGVALAVCFGFVLGSFM 432
            +     +  G + G  +
Sbjct: 425 IILAVTTIAAGALFGVVL 442


>UniRef50_B1LPU8 Anaerobic C4-dicarboxylate membrane transporter, DcuB family n=3
           Tax=Gammaproteobacteria RepID=B1LPU8_ECOSM
          Length = 438

 Score =  384 bits (987), Expect = e-105,   Method: Composition-based stats.
 Identities = 158/438 (36%), Positives = 244/438 (55%), Gaps = 8/438 (1%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLA-AIGVKPGNIPFDVISIIMAVIAA 59
           +  ++L IVL  I +G + GG+G+G  GGLGV +L    G+KP +     + II+ VI+A
Sbjct: 4   LFFIQLFIVLACIGIGGKYGGMGLGAGGGLGVAILVLGFGLKPSSPSITAMLIIICVISA 63

Query: 60  ISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVA 119
           +S +Q  GGLDYLV   E++LR+ P+ IT +API+T   T+F GT  ++ +  PVIAEVA
Sbjct: 64  VSILQAVGGLDYLVRVAERILRKKPQAITFVAPILTSVFTLFCGTTYVAFSLYPVIAEVA 123

Query: 120 KEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGH-GISYLHLLSVVIPSTLLA 178
            E  V+P R LS  V++A +A+ ASP+SAA   M +++  + GI+   +LS+ +PS  +A
Sbjct: 124 AEAKVRPERALSATVIAASVAVAASPMSAATAGMLAILHEYAGITLGQILSIALPSFFMA 183

Query: 179 VLVMSFLVTMLFNSKLSDDPIYRKRLEEGLV---ELRGEKQIEIKSGAKTSVWLFLLGVV 235
            +V SF V      +L DDP +++R+  G         +K+     GA+  V +F +GVV
Sbjct: 184 AIVTSFSVYK-RGKELEDDPEFQRRVAAGEYEFMHTEQKKEYVAAPGARKGVAIFAIGVV 242

Query: 236 GVVIYAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMS 295
            V+I             K  ++T   I +IML+ A L  ++ KV ++   + S F+AG+ 
Sbjct: 243 LVLILGSFTELLPSWDGK-RLSTPMVIQMIMLTAALLIMIVGKVPSNKFNSGSVFRAGLM 301

Query: 296 ACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALM 355
             + ILGV+W+  TF       + +  G ++   P L   I F  S ++ S AAT  A+M
Sbjct: 302 GVVAILGVSWMTATFFDAYQAELINVFGNLVNDAPLLFGFIVFLFSLVIMSPAATVAAIM 361

Query: 356 PMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGT 415
           P+ + L +     +A FA   G FI+P     +  V  D TGTTRIG+FV NH +  PG 
Sbjct: 362 PLGVTLGIPAPYLIAIFACTCGDFIIPG-ANQIGCVAFDRTGTTRIGRFVINHSYIRPGF 420

Query: 416 LGVALAVCFGFVLGSFML 433
           + V   V F +++   +L
Sbjct: 421 VMVISQVVFAYLIAQVIL 438


>UniRef50_D2TK06 Anaerobic C4-dicarboxylate transporter n=1 Tax=Citrobacter
           rodentium ICC168 RepID=D2TK06_CITRO
          Length = 429

 Score =  382 bits (982), Expect = e-104,   Method: Composition-based stats.
 Identities = 201/435 (46%), Positives = 290/435 (66%), Gaps = 10/435 (2%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAAIGVKPGNIPFDVISIIMAVIAAI 60
           M++V+ ++VLL +++G R+GGIG+GFAGG GV+VL+A+G  PG++P  VI  IM VI AI
Sbjct: 1   MILVQFLVVLLFLYIGMRVGGIGVGFAGGAGVIVLSALGATPGDMPMLVIVFIMVVIVAI 60

Query: 61  SAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAK 120
           +AMQ AGG++YLV  TE+LLRR P+ + I AP+ T+ LT+ A TG +S A +PVI  VAK
Sbjct: 61  AAMQEAGGIEYLVDLTERLLRRYPRLLVITAPLSTWLLTMMASTGQVSFACMPVIVGVAK 120

Query: 121 EQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEG--HGISYLHLLSVVIPSTLLA 178
           E  +KP R L+ +V ++ + I ASPISAAV++ S ++E    G  Y+ L++V IPST LA
Sbjct: 121 ENNIKPTRALALSVSASLLGIVASPISAAVIFFSGILEKGHSGWGYIELIAVSIPSTFLA 180

Query: 179 VLVMSFLVTMLFNSKLSDDPIYRK-RLEEGLVELRGEKQIEIKSGAKTSVWLFLLGVVGV 237
           +LV S        S L  D I ++ RL +  V+++   +  I   A  SV +F++G+V V
Sbjct: 181 LLVTSV-------SYLCWDRIRQQDRLYDNPVQVKARNERTIPPYAGRSVLIFIIGLVVV 233

Query: 238 VIYAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSAC 297
           ++YAI+ SP +GL+  P+M++  A + +ML VA L  V C+V+   + + S FK GM++C
Sbjct: 234 LVYAIVTSPKLGLIAHPVMSSGQARVEMMLGVALLIVVCCRVNVHKVPSGSVFKTGMTSC 293

Query: 298 ICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPM 357
           ICILGVAWLG TF+ +N  W++      +   P +LA+I   AS  LYSQAA+ K L P 
Sbjct: 294 ICILGVAWLGSTFMDSNQQWLQSAVSSHLLDSPIMLAIIIMAASCFLYSQAASTKILFPA 353

Query: 358 ALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLG 417
           AL++ ++P   VA F A S LFILP YPTL+AAV+MDDTG TR+G+ + +HPF +PG   
Sbjct: 354 ALSMGIAPAILVACFPATSSLFILPNYPTLLAAVEMDDTGYTRLGRHIIDHPFLLPGLAS 413

Query: 418 VALAVCFGFVLGSFM 432
           V L++ F   L   +
Sbjct: 414 VLLSMLFATGLAYLI 428


>UniRef50_UPI00019F11D6 anaerobic c4-dicarboxylate antiporter, Dcu family protein n=1
           Tax=Citrobacter youngae ATCC 29220 RepID=UPI00019F11D6
          Length = 428

 Score =  377 bits (968), Expect = e-103,   Method: Composition-based stats.
 Identities = 197/435 (45%), Positives = 282/435 (64%), Gaps = 10/435 (2%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAAIGVKPGNIPFDVISIIMAVIAAI 60
           M++V+  IVL+ +++G R+GGIG+GFAGG GVLVL  +G KPGN+P  VI  IM VI AI
Sbjct: 1   MVMVQFFIVLIFLYIGMRVGGIGVGFAGGAGVLVLGILGAKPGNMPMLVIVFIMVVIIAI 60

Query: 61  SAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAK 120
           SAMQ AGG+DYLV  TE+LLRR P+ + + API T+ LT+ A TG +S A +PVI  VAK
Sbjct: 61  SAMQEAGGIDYLVRLTERLLRRYPRLLVVTAPISTWLLTMMASTGQVSFACMPVIVGVAK 120

Query: 121 EQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVME--GHGISYLHLLSVVIPSTLLA 178
           E  +KP R L+ +V ++ + I ASPISAAV++ S ++E   HG  Y+ L+SV IP+T  A
Sbjct: 121 ENNIKPTRALALSVSASLLGIVASPISAAVIFFSGILEKNNHGWGYIELISVSIPATFFA 180

Query: 179 VLVMSFLVTMLFNSKLSDDPIYRK-RLEEGLVELRGEKQIEIKSGAKTSVWLFLLGVVGV 237
           +L  SF         L  D   ++ +L             E+  GA+ +V +F++G+V V
Sbjct: 181 LLFASFFY-------LCWDRFKQQDQLNNQPYIKEESIHQEVLPGARRAVLIFIIGLVVV 233

Query: 238 VIYAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSAC 297
           ++YAI+ SP +G++  P+MN+    + +M+ VA L    C+V+   I ++S FK GM++C
Sbjct: 234 LVYAIVASPKLGIISHPVMNSGQVRIGVMMGVALLIVACCRVNVHKISSTSVFKTGMTSC 293

Query: 298 ICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPM 357
           ICILGVAWLG TF+ NN  W++      +   PWLLA++    S  LYSQAA+ + L P 
Sbjct: 294 ICILGVAWLGSTFMDNNQQWLQAMVSGYLLHSPWLLALVIMLVSCFLYSQAASTQILFPA 353

Query: 358 ALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLG 417
           AL++ V+P   VA F A + LFILP YPTL+AAV++DDTG+T +G  + +HPF +PG + 
Sbjct: 354 ALSMGVAPGILVACFPATASLFILPNYPTLLAAVELDDTGSTHLGNKIIDHPFLLPGLIT 413

Query: 418 VALAVCFGFVLGSFM 432
             L++ F F L   +
Sbjct: 414 TLLSIAFAFALSLLI 428


>UniRef50_A7GZH5 Anaerobic C4-dicarboxylate transporter DcuA n=4 Tax=Proteobacteria
           RepID=A7GZH5_CAMC5
          Length = 423

 Score =  368 bits (944), Expect = e-100,   Method: Composition-based stats.
 Identities = 200/434 (46%), Positives = 279/434 (64%), Gaps = 14/434 (3%)

Query: 3   VVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAAI-GVKPGNIPFDVISIIMAVIAAIS 61
           ++E+I++   I L ARLGGIG+G AGGLG+++L  I GVKPG IP  V+ IIMAVI AIS
Sbjct: 1   MIEMIVLFGCIVLAARLGGIGVGLAGGLGLVILVFIMGVKPGEIPIAVMLIIMAVILAIS 60

Query: 62  AMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAKE 121
            MQ AGG+ Y+V  TE++LR +PKYI  LAP  T+ LT+  GTG  ++  L VI +VAKE
Sbjct: 61  VMQRAGGMAYMVKITERILRNHPKYINFLAPASTFILTVLTGTGYSAMTVLNVIQQVAKE 120

Query: 122 QGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAVLV 181
            GV+P +PLS+AVV++Q+AITASPISAA   +   +E  G+S+   L V++PS  +A LV
Sbjct: 121 NGVRPSQPLSSAVVASQLAITASPISAATAALYLTLEPMGVSFGSALMVIVPSAAIAALV 180

Query: 182 MSFLVTMLFNSKLSDDPIYRKRLEEGLVEL--RGEKQIEIKSGAKTSVWLFLLGVVGVVI 239
            +F+ +     +L DDPI+++R+++GLV      EK       AK SVWLFL  VV +VI
Sbjct: 181 AAFVASKQ-GVELKDDPIFQERVKKGLVSFESPEEKTARTTKEAKISVWLFLASVVFIVI 239

Query: 240 YAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSACIC 299
             +             +++ + I+I ML VA +    CKV  ++I  SS F +G  + I 
Sbjct: 240 MLLFKKQIGHD-----LSSRDIIVITMLFVAFVMVFPCKVPLEDIKKSSIFVSGAESFIV 294

Query: 300 ILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPMAL 359
           +LG+ WL  T +  +I  +K+ AGE+++ +P LLAVIFF  SA+L+SQ ATA  LMP+A 
Sbjct: 295 VLGITWLSSTAIGVHIPAVKEMAGELLKEYPALLAVIFFGTSAVLFSQGATAALLMPIAA 354

Query: 360 ALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLGVA 419
           +L V   T +ASF AVS L+I   YPT   A+  DDTG+     F+ NHPFF+PG L + 
Sbjct: 355 SLGVDAGTILASFVAVSALYITNIYPTTAFAISTDDTGS-----FIINHPFFLPGLLSIV 409

Query: 420 LAVCFGFVLGSFML 433
           ++V FGF L   +L
Sbjct: 410 VSVPFGFFLAKIVL 423


>UniRef50_A4N2Y1 Anaerobic C4-dicarboxylate transporter n=1 Tax=Haemophilus
           influenzae R3021 RepID=A4N2Y1_HAEIN
          Length = 389

 Score =  364 bits (936), Expect = 3e-99,   Method: Composition-based stats.
 Identities = 151/362 (41%), Positives = 218/362 (60%), Gaps = 8/362 (2%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVL-AAIGVKPGNIPFDVISIIMAVIAA 59
           M +++  IVLL IF+GAR+GGIG+G  GGLG+ +L    G+KP  +P DV+ +IMAV+AA
Sbjct: 4   MFLLQFAIVLLCIFVGARVGGIGLGVFGGLGLAILSFGFGLKPAGLPIDVMFMIMAVVAA 63

Query: 60  ISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVA 119
            +AMQ AGGLDY++    K+LRRNPK+IT +AP VT+  T+ AGTG+++ + LPVIAEV+
Sbjct: 64  AAAMQAAGGLDYMIKIATKILRRNPKHITFIAPAVTWLFTLLAGTGHVAYSVLPVIAEVS 123

Query: 120 KEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAV 179
           ++ G++P RP+S AV+++Q AI ASPI+AAVV + + +E  GI    +L V IPST+L +
Sbjct: 124 RQNGIRPERPMSMAVIASQFAIVASPIAAAVVAVVAYLEPQGIHLGDVLMVTIPSTILGL 183

Query: 180 LVMSFLVTMLFNSKLSDDPIYRKRLEEGLV-----ELRGEKQIEIKSGAKTSVWLFLLGV 234
            +    V  +   +L DDP Y++RL +             K++E+   AK SV LFL G 
Sbjct: 184 FLACLFVNKM-GKELKDDPEYQRRLNDPKYADIFASTTSVKEVEVSKTAKISVSLFLFGA 242

Query: 235 VGVVIYAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGM 294
           + VV+     S       KP M   + I IIMLS+  L  + CK D   I   S F AGM
Sbjct: 243 LLVVLMGAAPSIRPVFDGKP-MGMAHTIEIIMLSIGALIILTCKPDGTAITKGSVFHAGM 301

Query: 295 SACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKAL 354
            A I I G+AWLGDT +  +I  +K+    +++  PW  A   F    +       +  +
Sbjct: 302 RAVIAIFGIAWLGDTLMQAHITEVKEMVKGLVETAPWAFAFALFVTFCISKQPRRNSSNI 361

Query: 355 MP 356
           +P
Sbjct: 362 VP 363


>UniRef50_Q8CMX9 Anaerobic dicarboxylate transport n=11 Tax=Staphylococcus
           RepID=Q8CMX9_STAES
          Length = 444

 Score =  329 bits (844), Expect = 1e-88,   Method: Composition-based stats.
 Identities = 121/419 (28%), Positives = 230/419 (54%), Gaps = 17/419 (4%)

Query: 20  GGIGIG-FAGGLGVLVLAAIGVKPGNIPFDVISIIMAVIAAISAMQVAGGLDYLVHQTEK 78
           G +G G FA    ++++    + PG+ P   + II+++  A   +Q  GG+DYLV+   +
Sbjct: 35  GALGCGIFAIVAQLIMIFGFQLPPGSAPVTAVLIILSIGIAGGTLQATGGIDYLVYIASR 94

Query: 79  LLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAKEQGVKPCRPLSTAVVSAQ 138
           ++ R PK I  +AP++ +      GT NI+L+  P+IA+ A++  ++P R L+ +V++A 
Sbjct: 95  VIERFPKSIIFIAPMIVFVFVFGIGTANIALSLEPIIAKTAQKARIQPKRALTASVLTAN 154

Query: 139 IAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAVLVMSFLVTMLFNSKLSDDP 198
           +A+  SP ++A  Y+ SV+ G+ IS    LS+V+P+ L+++L++S   T +   +   D 
Sbjct: 155 LALLCSPAASATAYIISVLAGYEISMGKYLSIVLPTALISMLMLSTFCTFVGRKEHVRD- 213

Query: 199 IYRKRLEEGLVELRGEKQIEIKSGAKTSVWLFLLGVVGVVIYAIINSPSMGLVEK---PL 255
              + ++   VE++ +  +++    K  V  FLL V+G++ + I  +             
Sbjct: 214 ESERLVQMPEVEIKNDFSLKV----KIGVISFLLCVMGILTFGIFPNLMPQFNVNGDVVK 269

Query: 256 MNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSACICILGVAWLGDTFVSN-- 313
           +  T  +   M   AT+  ++ K++T +IL+S+  ++ M A   +LG  WLG T  +   
Sbjct: 270 VEMTEIVQFFMYLSATINLLLIKINTSDILSSNITQSAMGALFAVLGPGWLGATIFNAPH 329

Query: 314 NIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPMALALNVSPLTAVASFA 373
           N+  +K+  G +I   PWL+ ++    + ++ SQ ATA  ++P+ ++L + P+  VA   
Sbjct: 330 NLKILKNDIGSIISEVPWLVIILVSVVAMIVISQTATASIMVPIVMSLGIPPIYFVAMVQ 389

Query: 374 AVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLGVALAVCFGFVLGSFM 432
            ++  F++P  PTL+ AV++D+TG TR         F IPG   + ++V  GFV+ + +
Sbjct: 390 TLNVNFVIPAQPTLLFAVELDETGRTR------PTSFMIPGFFVITVSVITGFVIKTIL 442


>UniRef50_C5EXL5 Anaerobic C4-dicarboxylate transporter n=2 Tax=Proteobacteria
           RepID=C5EXL5_9HELI
          Length = 435

 Score =  328 bits (842), Expect = 2e-88,   Method: Composition-based stats.
 Identities = 168/311 (54%), Positives = 231/311 (74%), Gaps = 6/311 (1%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVL-AAIGVKPGNIPFDVISIIMAVIAA 59
           ML++++I++L AIF+G RLGGIGIG+AGG+GV++L   +G+ PG IP+DVI IIM+VIAA
Sbjct: 5   MLILQIIVLLGAIFVGIRLGGIGIGYAGGIGVIILGLGLGMTPGAIPWDVILIIMSVIAA 64

Query: 60  ISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVA 119
           ISAMQ+AGGLDYLV   E++LR NPKYI  LAP VTYFLTI AGTG+ + + +PVI EVA
Sbjct: 65  ISAMQLAGGLDYLVQIAERILRSNPKYINYLAPTVTYFLTILAGTGHTAFSMIPVIVEVA 124

Query: 120 KEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAV 179
           KEQ +KP  PLS AVVS+QIAITASP+SAAVVYM+ V+E  G SY  LL + IP+T +  
Sbjct: 125 KEQNIKPSAPLSIAVVSSQIAITASPVSAAVVYMTGVLEPLGWSYPLLLGIWIPTTFVGC 184

Query: 180 LVMSFLVTMLFNSKLSDDPIYRKRLEEGLVELR-GEKQIEIKSGAKTSVWLFLLGVVGVV 238
           ++ +F++TM ++  LS DP+Y++RL +GLV+   G + +E+K GAK SV +F++GV+ VV
Sbjct: 185 MITAFIMTMFYDLDLSKDPVYQERLAQGLVKAPVGAQNMELKEGAKLSVAIFVIGVLCVV 244

Query: 239 IYAIINSP---SMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMS 295
           +YA   S       L+E  ++    AI+  ML +ATL  ++CK+  D I ++S FK+GM 
Sbjct: 245 LYATAISKIGGKPVLIENVIVGRDAAIMSFMLGIATLIVMLCKIKPDKIADTSVFKSGMV 304

Query: 296 ACICI-LGVAW 305
           AC+CI   +AW
Sbjct: 305 ACVCIGCSLAW 315


>UniRef50_A7ZC15 Anaerobic C4-dicarboxylate membrane transporter n=31
           Tax=Proteobacteria RepID=A7ZC15_CAMC1
          Length = 559

 Score =  282 bits (721), Expect = 3e-74,   Method: Composition-based stats.
 Identities = 85/278 (30%), Positives = 143/278 (51%), Gaps = 17/278 (6%)

Query: 2   LVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAA-IGVKPGNIPFDVISIIMAVIAAI 60
             ++LI+VL  +F GA+ GG+ +G  GG+G+++L     +KPG    DVI  I+AV+ A 
Sbjct: 13  FFLQLIVVLGCLFYGAKKGGMALGVLGGIGLVILVFAFDLKPGKPAIDVILTILAVVVAS 72

Query: 61  SAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAK 120
           + +Q AGGLD ++   E+ LR++P+ +  LAPI  + LT+  GTG+     LP+I +V+ 
Sbjct: 73  ATLQAAGGLDVMLQIAERALRKHPRTVCYLAPICGWTLTVLCGTGHTVYTLLPIIYDVSM 132

Query: 121 EQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHG-------ISYLHLLSVVIP 173
           + G++P RP++   +S+Q+AI ASP+S A V M +V+ G G        SY+ LL V IP
Sbjct: 133 KSGIRPERPMAATTISSQLAIIASPVSVAGVSMVAVLLGTGTVHIEGFTSYVDLLKVTIP 192

Query: 174 STLLAVLVMSFLVTMLFNSKLSDDPIYRKRLEEGLVELR--------GEKQIEIKSGAKT 225
           ST L VL +    ++     L  DP ++ ++ +                  +++      
Sbjct: 193 STFLGVLCIGT-YSVFRGKDLDKDPEFQAKIADPEQRKYIYGSDESHSLIGVKLPKKQWN 251

Query: 226 SVWLFLLGVVGVVIYAIINSPSMGLVEKPLMNTTNAIL 263
            +W+FL  +  V +                  +   I+
Sbjct: 252 IMWIFLATIAVVAVLGYYKQLRPSWTSNVPGKSIEIIV 289



 Score =  223 bits (568), Expect = 1e-56,   Method: Composition-based stats.
 Identities = 67/180 (37%), Positives = 104/180 (57%)

Query: 252 EKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSACICILGVAWLGDTFV 311
           +   +   + I I ML  A++  +   +    I  +  F +GM A + I G++W+ +T  
Sbjct: 375 KTAPLGMVDTIQIFMLLAASIMMIYSGIKAAKIGQNEIFHSGMVALVAIYGISWMAETMF 434

Query: 312 SNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPMALALNVSPLTAVAS 371
           +++ID +K + GEV++ +PW+  ++    S  L SQAA A   +P+A+ + V P   VA 
Sbjct: 435 NSHIDMLKGSLGEVMKAYPWMYIIVGMLISKFLNSQAAAAATFVPLAVQIGVHPGVIVAF 494

Query: 372 FAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLGVALAVCFGFVLGSF 431
             A  G FILPTYP+ +AAVQ D +GTT IGK+V NH F IPG +GV  +   G+VL + 
Sbjct: 495 ATACYGYFILPTYPSDLAAVQFDRSGTTHIGKYVINHSFIIPGFIGVFSSCAVGWVLANI 554


>UniRef50_C6MSZ8 Anaerobic c4-dicarboxylate antiporter, Dcu family n=2
           Tax=Proteobacteria RepID=C6MSZ8_9DELT
          Length = 546

 Score =  270 bits (692), Expect = 5e-71,   Method: Composition-based stats.
 Identities = 117/280 (41%), Positives = 168/280 (60%), Gaps = 18/280 (6%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAA-IGVKPGNIPFDVISIIMAVIAA 59
           M  +E ++VL AIF+GARLGGIG+G  GGLG+ +L     ++P   P DV+ +I AV+ A
Sbjct: 1   MFWLEFLVVLAAIFIGARLGGIGLGVMGGLGLALLTFLFHLQPTAPPIDVMLMIAAVVTA 60

Query: 60  ISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVA 119
              +Q AGGLDYLV   EK+LR NP  IT L P+VTYF T+FAGTG+++ + LPVIAEVA
Sbjct: 61  AGVLQAAGGLDYLVSLAEKILRNNPDRITFLGPMVTYFFTLFAGTGHVAYSVLPVIAEVA 120

Query: 120 KEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVM------EGHGISYLHLLSVVIP 173
           +E GV+P RP+S AV+++Q AITASPI+AA V +  ++       G  +  + +L V IP
Sbjct: 121 RETGVRPERPMSIAVIASQQAITASPIAAATVALLGLLGGSAAKFGFNVELIDILKVCIP 180

Query: 174 STLLAVLVMSFLVTMLFNSKLSDDPIYRKRLEEGLVELRGEKQIE----------IKSGA 223
           STL+ VL+ +F+   L    L  DP Y++RL+EGLV        +            + A
Sbjct: 181 STLMGVLIAAFISNKL-GKDLDKDPEYQQRLKEGLVPPPRSSSSDTAKVNEAIRNTPASA 239

Query: 224 KTSVWLFLLGVVGVVIYAIINSPSMGLVEKPLMNTTNAIL 263
           K +V LFL+G + VV++                  ++ ++
Sbjct: 240 KVAVALFLVGTILVVLFGSFPQLRPEWSVGNDTRISHIVV 279



 Score =  224 bits (571), Expect = 6e-57,   Method: Composition-based stats.
 Identities = 76/191 (39%), Positives = 110/191 (57%), Gaps = 1/191 (0%)

Query: 243 INSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSACICILG 302
            +        K  M   + I I+ML++A L  ++CKV    +   S F AG+ A I I G
Sbjct: 357 FDEKRPAQN-KEKMGMPHVIEIVMLAIAALMLLLCKVKVSRVAEGSVFIAGVQAVIAIFG 415

Query: 303 VAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPMALALN 362
           +AW+GDTF   N++++  +   ++   PWL A   F  S LLYSQAAT +ALMP+ ++L 
Sbjct: 416 IAWMGDTFFQGNMEFLSGSIKGMVTTAPWLFAFALFILSILLYSQAATVRALMPLGISLG 475

Query: 363 VSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLGVALAV 422
           +     +A F AV+G F +P YPT+VAA+  D TGTT IG++V NH F IPG +    ++
Sbjct: 476 IPAPFLIAMFPAVNGYFFIPNYPTVVAAINFDRTGTTGIGRWVLNHSFMIPGLVATFSSI 535

Query: 423 CFGFVLGSFML 433
             GF+L   M 
Sbjct: 536 GIGFLLVKLMF 546


>UniRef50_Q2EX27 DcuA (Fragment) n=20 Tax=Bacteria RepID=Q2EX27_ECOLX
          Length = 180

 Score =  218 bits (555), Expect = 4e-55,   Method: Composition-based stats.
 Identities = 180/180 (100%), Positives = 180/180 (100%)

Query: 241 AIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSACICI 300
           AIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSACICI
Sbjct: 1   AIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSACICI 60

Query: 301 LGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPMALA 360
           LGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPMALA
Sbjct: 61  LGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPMALA 120

Query: 361 LNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLGVAL 420
           LNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLGVAL
Sbjct: 121 LNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLGVAL 180


>UniRef50_UPI0001854D97 anaerobic C4-dicarboxylate transporter n=1 Tax=Helicobacter pylori
           HPKX_438_CA4C1 RepID=UPI0001854D97
          Length = 170

 Score =  170 bits (431), Expect = 1e-40,   Method: Composition-based stats.
 Identities = 72/171 (42%), Positives = 107/171 (62%), Gaps = 2/171 (1%)

Query: 122 QGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAVLV 181
           + +KP  PLS AVVS+Q+AITASP+SAAVV+MS ++E  G +YL LL V IP+T LA ++
Sbjct: 1   KTIKPKAPLSLAVVSSQVAITASPVSAAVVFMSGILEPLGANYLTLLMVWIPTTFLACMI 60

Query: 182 MSFLVTMLFNSKLSDDPIYRKRLE-EGLVELRGEKQIEIKSGAKTSVWLFLLGVVGVVIY 240
            +F++    + +L  DP Y +RL          +++ E    AK S+W+F+ GVV +V Y
Sbjct: 61  TAFMMGFT-DLRLDSDPNYLERLNTRNFSPPTIKEEKETSKSAKLSLWIFIGGVVAIVFY 119

Query: 241 AIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFK 291
           A   S ++  V   ++    AI+  MLSVATL  + CK++ + I +SS FK
Sbjct: 120 ASAISKNIAFVSPVVLGRDYAIVSFMLSVATLIVLFCKINANEIAHSSVFK 170


>UniRef50_P40684 Anaerobic C4-dicarboxylate transporter dcuA (Fragment) n=7
           Tax=Proteobacteria RepID=DCUA_SERMA
          Length = 132

 Score =  137 bits (346), Expect = 7e-31,   Method: Composition-based stats.
 Identities = 121/132 (91%), Positives = 127/132 (96%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAAIGVKPGNIPFDVISIIMAVIAAI 60
           ML VEL+IVLLAIFLGARLGGIGIGFAGGLGVL LA IGVKPGNIPFDVISIIMAVIAAI
Sbjct: 1   MLAVELVIVLLAIFLGARLGGIGIGFAGGLGVLALALIGVKPGNIPFDVISIIMAVIAAI 60

Query: 61  SAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAK 120
           SAMQVAGG+DYLV QTEKLLR+NPK+ITILAPIVTYFLTIFAGTGNISL+ LPVIAEVAK
Sbjct: 61  SAMQVAGGMDYLVQQTEKLLRKNPKHITILAPIVTYFLTIFAGTGNISLSALPVIAEVAK 120

Query: 121 EQGVKPCRPLST 132
           EQG+KPCRPLST
Sbjct: 121 EQGIKPCRPLST 132


>UniRef50_UPI00019127C3 anaerobic C4-dicarboxylate transporter n=1 Tax=Salmonella enterica
           subsp. enterica serovar Typhi str. AG3
           RepID=UPI00019127C3
          Length = 99

 Score =  107 bits (267), Expect = 9e-22,   Method: Composition-based stats.
 Identities = 87/99 (87%), Positives = 95/99 (95%)

Query: 182 MSFLVTMLFNSKLSDDPIYRKRLEEGLVELRGEKQIEIKSGAKTSVWLFLLGVVGVVIYA 241
           MSFLVTMLFNSKLSDDPIYRKRLEEGL+ELRGEKQIEIK  AK SVWLFLLGV+ VV+YA
Sbjct: 1   MSFLVTMLFNSKLSDDPIYRKRLEEGLIELRGEKQIEIKPMAKNSVWLFLLGVICVVVYA 60

Query: 242 IINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVD 280
           I+NSPS+GLVEKPLMNTTNAILIIMLSVATLTT++CKV+
Sbjct: 61  IVNSPSLGLVEKPLMNTTNAILIIMLSVATLTTILCKVE 99


>UniRef50_Q1CLI8 Anaerobic C4-dicarboxylate transporter n=8 Tax=Yersinia pestis
           RepID=Q1CLI8_YERPN
          Length = 103

 Score = 94.5 bits (234), Expect = 7e-18,   Method: Composition-based stats.
 Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 3/93 (3%)

Query: 239 IYAIINSPSMGLVEKPLM---NTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMS 295
           +             K  +   +    I ++ML    +  + CKV   +I N + FKAGM 
Sbjct: 1   MLGAFADLRPAFEVKGKLQSLSMNLVIQMMMLIAGAVILIGCKVKPSDISNGAVFKAGMV 60

Query: 296 ACICILGVAWLGDTFVSNNIDWIKDTAGEVIQG 328
           A   + GVAW+ DTF   ++  ++    +V++ 
Sbjct: 61  AIFSVFGVAWMSDTFFQAHMGELRLVLEDVVKA 93


>UniRef50_C3HV44 Anaerobic C4-dicarboxylate transporter dcuB n=1 Tax=Bacillus
           thuringiensis IBL 200 RepID=C3HV44_BACTU
          Length = 134

 Score = 85.7 bits (211), Expect = 4e-15,   Method: Composition-based stats.
 Identities = 52/117 (44%), Positives = 76/117 (64%), Gaps = 6/117 (5%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAA-IGVKPGNIPFDVISIIMAVIAA 59
           M  ++ + +LL IF+GARLGG+G+G  GG+G+ +L     ++P   P DV+ +I+AVI A
Sbjct: 1   MFWLQFLTLLLCIFIGARLGGVGLGVMGGVGMAILVFVFHLQPTAPPIDVMLMILAVITA 60

Query: 60  ISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIA 116
             A+Q AGG+DYLVH  EK LR+NPK IT L  +    L I++    + L TLP++ 
Sbjct: 61  AGALQAAGGMDYLVHLAEKALRKNPKRITFLLQL----LLIYSHYVQV-LVTLPILY 112


>UniRef50_UPI00019127C2 anaerobic C4-dicarboxylate transporter n=1 Tax=Salmonella enterica
           subsp. enterica serovar Typhi str. AG3
           RepID=UPI00019127C2
          Length = 60

 Score = 43.7 bits (102), Expect = 0.012,   Method: Composition-based stats.
 Identities = 30/32 (93%), Positives = 32/32 (100%)

Query: 150 VVYMSSVMEGHGISYLHLLSVVIPSTLLAVLV 181
           +VYMSSVMEGHGISY+HLLSVVIPSTLLAVLV
Sbjct: 1   MVYMSSVMEGHGISYIHLLSVVIPSTLLAVLV 32


>UniRef50_P25360 Inorganic phosphate transporter PHO87 n=19 Tax=Saccharomycetaceae
           RepID=PHO87_YEAST
          Length = 923

 Score = 42.5 bits (99), Expect = 0.028,   Method: Composition-based stats.
 Identities = 53/277 (19%), Positives = 100/277 (36%), Gaps = 46/277 (16%)

Query: 71  YLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAKEQGVKPCRPL 130
           +L+          P+ + ++A  V +FL+++    N++   L           +    P 
Sbjct: 572 WLLALAGT----KPRNVLLMAMSVVFFLSMWI--SNVASPVLTYSLLTPLLDPLDYTSPF 625

Query: 131 STAVV-----SAQIAITASPISAA--VVYMSSVMEGHGISYLHLLSVVIPSTLLAVLV-- 181
           + A+V     SA I   ASPIS+   ++ M   ++ +GI +    +V +P+ +L++L   
Sbjct: 626 AKALVMGVALSADIGGMASPISSPQNIISM-QYLKPYGIGWGQFFAVALPTGILSMLCSW 684

Query: 182 MSFLVTMLFNS-KLSDDPIYRKRLEEG-------------LVELRGEKQIEIKSGAKTS- 226
              ++T      KL      R R                 L  +  + +    S  + + 
Sbjct: 685 ALMILTFKIGKTKLEKFKPIRTRFTIKQYFIIIVTIATILLWCVESQIESAFGSSGEIAV 744

Query: 227 ---VWLFLLGVVGVVIYAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDN 283
              V  F  G++    +              ++      L   +S + L   I +     
Sbjct: 745 IPIVLFFGTGLLSTKDFNTFP------WSIVVLAMGGIALGKAVSSSGLLVTIARALQKK 798

Query: 284 ILNSSTFKAGMSACICILGVAWL-GDTFVSNNIDWIK 319
           I N   F     A +CI G+  L   TFVS+ +  I 
Sbjct: 799 IQNDGVF-----AILCIFGILMLVVGTFVSHTVSAII 830


>UniRef50_Q03HQ5 C4-dicarboxylate transporter n=5 Tax=Bacteria RepID=Q03HQ5_PEDPA
          Length = 467

 Score = 42.1 bits (98), Expect = 0.036,   Method: Composition-based stats.
 Identities = 77/397 (19%), Positives = 152/397 (38%), Gaps = 28/397 (7%)

Query: 51  SIIMAVIAAISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFA----GTGN 106
            +I+ +    + M   G     VH   K + +  K I +LAPIV     + +       N
Sbjct: 79  FVILILGGYSAYMNHIGANQVTVHALTKPITKI-KSIYLLAPIVFLIGNLLSLVIPSASN 137

Query: 107 ISLATLPVIAEVAKEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSV--MEGHGISY 164
           +++  L  +  V +  G+   R  S A++     I  +P+ A  V ++S   M      +
Sbjct: 138 LAIILLATLYPVLRSAGM--SRLTSAAIIGTSATIVPTPLGADNVAIASQFHMSVTDYVF 195

Query: 165 LHLLSVVIPSTLLAVLVMSFLVTMLFNSKLSDDPIYRKRLEEGLVELRGEKQIEIKSGAK 224
                + IP TLLA+ ++ +L     + K  ++  Y   L +   +           G K
Sbjct: 196 QKHALISIP-TLLAITIVHYLWQKYQDKKHPEELSYSSELSQNKEQDSTASPKVSYKGFK 254

Query: 225 TSVWLFLLGVVGVVIYAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNI 284
              +++ L  +  ++  +I   +   +   L  +   + ++   +A L  +  K     +
Sbjct: 255 --AFIYGLLPLLPIVILLIIFFTNIFLHTKLNISVQLVSLLSFVIAVLVEIFNKKHPQIV 312

Query: 285 LN-SSTFKAGMSACICILGVAWLGDTFVSNN-----IDWIKDTAGEVIQGHPWLLAVIFF 338
           L  +S F  GM + + I+ +      FV        ID I+ T   +      L  V+  
Sbjct: 313 LKETSNFFEGMGSVMSIVALLVSAQVFVQGLTSIGIIDLIQKTMQTMNSSGIVLPVVMVV 372

Query: 339 FASALLYSQA-------ATAKALMPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAV 391
           F + ++           A    L+P++ A  +SP+        ++G  +    P  VAAV
Sbjct: 373 FTAIIVLLSGSGTALLYAMIPLLLPLSKAAGISPIALSVPMQ-LAGNLLRAISP--VAAV 429

Query: 392 QMDDTGTTRIGKFVFNHPFFIPGTLGVALAVCFGFVL 428
            +   GTT++          +P   GV + +    ++
Sbjct: 430 ILIVAGTTKLSPVKIVKRTSVPMVFGVIMMLVMSLLI 466


>UniRef50_C3KGP7 MIP04527p (Fragment) n=9 Tax=Sophophora RepID=C3KGP7_DROME
          Length = 708

 Score = 41.7 bits (97), Expect = 0.053,   Method: Composition-based stats.
 Identities = 34/202 (16%), Positives = 81/202 (40%), Gaps = 9/202 (4%)

Query: 31  GVLVLAAIGVKPGN------IPFDVISIIMAVIAAISAMQVAGGLDYLVHQTEKLLRRNP 84
           G+ +L A+G +P        I F+ + +++ ++  ++ M   G  D++     ++ + NP
Sbjct: 251 GIAILTALGNRPTLETIISWIDFETLILLLGMMILVAIMSETGVFDWMAVLAYRISKGNP 310

Query: 85  KYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAKEQGVKPCRPLSTAVVSAQIAITAS 144
             + +L   +T  ++       + L   P+   + +   V+    L   V+ + I  T +
Sbjct: 311 WPMLLLLSSITAIMSCMLDNVTMLLLMAPIAIRLCEAMAVQTPLVLIVVVMYSNIGGTLT 370

Query: 145 PIS---AAVVYMSSVMEGHGISYLHLLSVVIPSTLLAVLVMSFLVTMLFNSKLSDDPIYR 201
           P+      ++  +S +   G+ +L     ++P  LLA +    ++ +     L      +
Sbjct: 371 PVGDPPNVIIATNSEVISAGVDFLDFTIHMLPGVLLAAVAGYAVMYVTMRKSLFKLEEQQ 430

Query: 202 KRLEEGLVELRGEKQIEIKSGA 223
             L       R     +I + A
Sbjct: 431 LELAAERENSRRRSSADITARA 452


>UniRef50_C4XIX1 Arsenical pump membrane protein n=1 Tax=Desulfovibrio magneticus
           RS-1 RepID=C4XIX1_DESMR
          Length = 445

 Score = 41.0 bits (95), Expect = 0.099,   Method: Composition-based stats.
 Identities = 32/148 (21%), Positives = 67/148 (45%), Gaps = 2/148 (1%)

Query: 47  FDVISIIMAVIAAISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGN 106
           ++VI ++++++  ++ M   G   Y+  +  K+ R  P  I  +  +VT   + F     
Sbjct: 55  WNVIFLLISMMIMVNIMTKTGVFQYVAVRAAKIARGEPFAIMAILAVVTALASAFLDNVT 114

Query: 107 ISLATLPVIAEVAKEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLH 166
             L   PV   VAKE  + P   L T  +++ I  TA+ I      M +     G+ ++ 
Sbjct: 115 TVLLLAPVTLLVAKELEIDPVPFLITEALASNIGGTATLIGDPPNIMIASKA--GLDFMD 172

Query: 167 LLSVVIPSTLLAVLVMSFLVTMLFNSKL 194
            +  + P+ ++ +    F+  ++F  +L
Sbjct: 173 FIVHLTPAIIIVMAAWMFVWKLVFGQRL 200


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_A1JIN9 Anaerobic C4-dicarboxylate transporter n=79 Tax=...   463   e-129
UniRef50_Q7MDX2 Anaerobic C4-dicarboxylate transporter n=104 Tax...   458   e-127
UniRef50_A7I3J6 Anaerobic C4-dicarboxylate transporter DcuA n=8 ...   453   e-126
UniRef50_C9R1M8 Anaerobic C4-dicarboxylate membrane transporter ...   453   e-126
UniRef50_P44855 Anaerobic C4-dicarboxylate transporter dcuB n=16...   448   e-124
UniRef50_B4CX44 Anaerobic c4-dicarboxylate antiporter, Dcu famil...   448   e-124
UniRef50_Q5HVA4 Anaerobic C4-dicarboxylate membrane transporter ...   439   e-122
UniRef50_C8N6Y6 Anaerobic C4-dicarboxylate transporter DcuB n=1 ...   438   e-121
UniRef50_C6CN04 Anaerobic c4-dicarboxylate antiporter, Dcu famil...   438   e-121
UniRef50_Q5E4K5 Anaerobic C4-dicarboxylate transporter n=16 Tax=...   431   e-119
UniRef50_Q9ZLC0 Anaerobic C4-dicarboxylate transporter dcuA n=22...   430   e-119
UniRef50_P0ABP1 Anaerobic C4-dicarboxylate transporter dcuB n=13...   427   e-118
UniRef50_B4UMD4 Anaerobic c4-dicarboxylate antiporter, Dcu famil...   426   e-118
UniRef50_Q7NRZ2 Anaerobic C4-dicarboxylate membrane transporter ...   423   e-117
UniRef50_B4TYZ8 Anaerobic C4-dicarboxylate transporter DcuA n=30...   423   e-117
UniRef50_D1P157 Anaerobic C4-dicarboxylate transporter DcuB n=2 ...   422   e-116
UniRef50_B6EGF2 Anaerobic c4-dicarboxylate transporter DcuB n=1 ...   399   e-109
UniRef50_C3JGC7 C4-dicarboxylate membrane transporter n=2 Tax=Rh...   392   e-107
UniRef50_B1LPU8 Anaerobic C4-dicarboxylate membrane transporter,...   381   e-104
UniRef50_D2TK06 Anaerobic C4-dicarboxylate transporter n=1 Tax=C...   379   e-103
UniRef50_UPI00019F11D6 anaerobic c4-dicarboxylate antiporter, Dc...   378   e-103
UniRef50_A7GZH5 Anaerobic C4-dicarboxylate transporter DcuA n=4 ...   364   3e-99
UniRef50_A4N2Y1 Anaerobic C4-dicarboxylate transporter n=1 Tax=H...   363   9e-99
UniRef50_C5EXL5 Anaerobic C4-dicarboxylate transporter n=2 Tax=P...   327   7e-88
UniRef50_Q8CMX9 Anaerobic dicarboxylate transport n=11 Tax=Staph...   327   7e-88
UniRef50_A7ZC15 Anaerobic C4-dicarboxylate membrane transporter ...   282   1e-74
UniRef50_C6MSZ8 Anaerobic c4-dicarboxylate antiporter, Dcu famil...   270   9e-71
UniRef50_Q2EX27 DcuA (Fragment) n=20 Tax=Bacteria RepID=Q2EX27_E...   215   3e-54
UniRef50_UPI0001854D97 anaerobic C4-dicarboxylate transporter n=...   169   2e-40
UniRef50_P40684 Anaerobic C4-dicarboxylate transporter dcuA (Fra...   136   1e-30
UniRef50_UPI00019127C3 anaerobic C4-dicarboxylate transporter n=...   104   5e-21
UniRef50_Q1CLI8 Anaerobic C4-dicarboxylate transporter n=8 Tax=Y...    93   1e-17
UniRef50_C3HV44 Anaerobic C4-dicarboxylate transporter dcuB n=1 ...    85   6e-15

Sequences not found previously or not previously below threshold:

UniRef50_UPI00019127C2 anaerobic C4-dicarboxylate transporter n=...    43   0.017
UniRef50_Q03HQ5 C4-dicarboxylate transporter n=5 Tax=Bacteria Re...    43   0.021
UniRef50_P25360 Inorganic phosphate transporter PHO87 n=19 Tax=S...    42   0.040
UniRef50_C3KGP7 MIP04527p (Fragment) n=9 Tax=Sophophora RepID=C3...    42   0.054


CONVERGED!
>UniRef50_A1JIN9 Anaerobic C4-dicarboxylate transporter n=79 Tax=Bacteria
           RepID=A1JIN9_YERE8
          Length = 433

 Score =  463 bits (1191), Expect = e-129,   Method: Composition-based stats.
 Identities = 370/433 (85%), Positives = 401/433 (92%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAAIGVKPGNIPFDVISIIMAVIAAI 60
           M+ VEL+IVLLAIFLGARLGGIGIGFAGG+GVLVLA IGVKPG+IPFDVISIIMAVIAAI
Sbjct: 1   MIAVELVIVLLAIFLGARLGGIGIGFAGGIGVLVLAIIGVKPGSIPFDVISIIMAVIAAI 60

Query: 61  SAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAK 120
           SAMQVAGG+DYLV QTEKLLR+NPK+ITILAP+VTYFLTIFAGTGNISL+ LPVIAEVAK
Sbjct: 61  SAMQVAGGMDYLVQQTEKLLRKNPKHITILAPLVTYFLTIFAGTGNISLSALPVIAEVAK 120

Query: 121 EQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAVL 180
           EQG+KPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHG+SYLHLL +VIPSTLLAV 
Sbjct: 121 EQGIKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGVSYLHLLMIVIPSTLLAVF 180

Query: 181 VMSFLVTMLFNSKLSDDPIYRKRLEEGLVELRGEKQIEIKSGAKTSVWLFLLGVVGVVIY 240
           VMS +V+  FNSKLSDDPIY KRLEEGLV LRG+    IK  AKTSV LFL GV+ VV Y
Sbjct: 181 VMSLIVSWCFNSKLSDDPIYIKRLEEGLVTLRGDTVKVIKPRAKTSVLLFLAGVLCVVAY 240

Query: 241 AIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSACICI 300
           AIINSPS+GLV  PLMNTTNAILIIMLSVAT+TT++C VDTD+ILNSSTFKAGMSACICI
Sbjct: 241 AIINSPSVGLVATPLMNTTNAILIIMLSVATITTMVCSVDTDSILNSSTFKAGMSACICI 300

Query: 301 LGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPMALA 360
           LGVAWLGDTFV +N+DWIK+TAG +IQ H WLLAVIFFF SALLYSQAATAKALMPMA+A
Sbjct: 301 LGVAWLGDTFVQHNLDWIKETAGSLIQAHSWLLAVIFFFCSALLYSQAATAKALMPMAMA 360

Query: 361 LNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLGVAL 420
           LNVSPL A+ASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIG+FVFNHPFFIPGT+GVAL
Sbjct: 361 LNVSPLAAIASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGRFVFNHPFFIPGTIGVAL 420

Query: 421 AVCFGFVLGSFML 433
           AVCFGFV+G  +L
Sbjct: 421 AVCFGFVMGGLVL 433


>UniRef50_Q7MDX2 Anaerobic C4-dicarboxylate transporter n=104 Tax=cellular organisms
           RepID=Q7MDX2_VIBVY
          Length = 467

 Score =  458 bits (1180), Expect = e-127,   Method: Composition-based stats.
 Identities = 155/428 (36%), Positives = 250/428 (58%), Gaps = 10/428 (2%)

Query: 15  LGARLGGIGIGFAGGLGVLVLAA-IGVKPGNIPFDVISIIMAVIAAISAMQVAGGLDYLV 73
           +G+R GGIG+G   G+G+++      + P + P  V+ II+AV+   S ++ AGGL Y++
Sbjct: 40  IGSRYGGIGLGVVSGIGLVIEVFVFKMPPTSPPVTVMLIILAVVTCASILEAAGGLKYML 99

Query: 74  HQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAKEQGVKPCRPLSTA 133
              E++LR+NPK +T++AP VTY +T   GTG+   + +P+I +VA + G++P RP++ A
Sbjct: 100 QVAERMLRKNPKRVTLIAPFVTYTMTFMLGTGHAVYSIMPIIGDVALKNGIRPERPMAAA 159

Query: 134 VVSAQIAITASPISAAVVYMSSVME--GHGISYLHLLSVVIPSTLLAVLVMSFLVTMLFN 191
            V++QIAITASPISAAVVY  + +    H I+ L +L V +P+TL   L+MS L +M   
Sbjct: 160 SVASQIAITASPISAAVVYYLAQLSDINHEITLLSILLVTVPATLFGTLLMS-LYSMKRG 218

Query: 192 SKLSDDPIYRKRLEEGLVELR------GEKQIEIKSGAKTSVWLFLLGVVGVVIYAIINS 245
            +L DDP Y+ RL++ +   +            + + A+ SV LF+L ++ +V+ A+I  
Sbjct: 219 KELEDDPEYQARLKDPVWREKILNTTATSLDEHLPAAARNSVLLFILSILTIVVIAMIPE 278

Query: 246 PSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSACICILGVAW 305
             +       ++    I ++ML    +  +  K D  ++ N   FK+GM A I I G+AW
Sbjct: 279 VRIIGEGTKPISMAVVIQMMMLCFGGIILLATKTDPRSVPNGVVFKSGMVAAIAIFGIAW 338

Query: 306 LGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPMALALNVSP 365
           + DT+    +   K    E++  +PW  A+  F  S ++ SQAA A+ ++P+ L L + P
Sbjct: 339 MSDTYFQYAMPQFKSGIVEMVNNYPWTFALALFIVSVVVNSQAAVARMMLPVGLGLGLEP 398

Query: 366 LTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLGVALAVCFG 425
              V    A+ G F +P YP+ +A V  D+TGTT+IGK+ FNH F   G +GV  A C G
Sbjct: 399 ALLVGLMPALYGYFFIPNYPSDIATVNFDNTGTTKIGKWYFNHSFMSVGLIGVIGACCLG 458

Query: 426 FVLGSFML 433
           ++LG  ++
Sbjct: 459 YLLGQMII 466


>UniRef50_A7I3J6 Anaerobic C4-dicarboxylate transporter DcuA n=8 Tax=Bacteria
           RepID=A7I3J6_CAMHC
          Length = 497

 Score =  453 bits (1166), Expect = e-126,   Method: Composition-based stats.
 Identities = 255/494 (51%), Positives = 329/494 (66%), Gaps = 61/494 (12%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAAIGVKPGNIPFDVISIIMAVIAAI 60
           ML++E+I++L AIFLG +LGG+ IG+AGGLGV++L  +G+K G+IP+DVI II +VI+AI
Sbjct: 4   MLILEIIVLLGAIFLGVKLGGMAIGYAGGLGVVILTMLGLKAGSIPWDVILIIASVISAI 63

Query: 61  SAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAK 120
           +AMQVAGGLDYLV   EKLLR+NPKY+  LAP VTY LTIFAGTG+ + + +PVIAEVAK
Sbjct: 64  AAMQVAGGLDYLVQLAEKLLRKNPKYVNFLAPTVTYLLTIFAGTGHTAFSMIPVIAEVAK 123

Query: 121 EQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVME--GHGISYLHLLSVVIPSTLLA 178
            Q +KP  PLS AVVS+QIAITASP+SAAV++M+  M   G GISY  LL++ IP+T L 
Sbjct: 124 GQNIKPSVPLSIAVVSSQIAITASPVSAAVIFMAGDMALGGLGISYPILLAIWIPTTFLG 183

Query: 179 VLVMSFLVTMLFNSKLSDDPIYRKRLEEGLVELRGE--KQIEIKSGAKTSVWLFLLGVVG 236
            ++ + ++ + +N KL  DP+Y+ RL +GLV    +  K  E+  GAKTSV +F +G++ 
Sbjct: 184 CMITALIMNLFWNLKLDSDPVYKDRLAKGLVAEPQKEGKYKELPKGAKTSVLIFFIGIIA 243

Query: 237 VVIYAIINSPSMGLVEKP------------------------------------------ 254
           VV YA   S ++ LV+                                            
Sbjct: 244 VVFYATAISKNVALVKPSYVTGYEKVYQSKDAAKFDEIIAANPNIKISTDKDTGVKYVED 303

Query: 255 --------LMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSACICILGVAWL 306
                    +    AI+  ML +  L  +ICK+D D I   STFK+GM+ACIC+LGVAWL
Sbjct: 304 KSKPKKSLTLARDGAIMSFMLIIGALIVMICKIDVDKIPVQSTFKSGMTACICVLGVAWL 363

Query: 307 GDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMP-MALALNV-- 363
           GDTFVSN+   IKD AG +++ +P LL+V  FFAS LLYSQAATAKAL+P + +AL +  
Sbjct: 364 GDTFVSNHTQEIKDFAGNLVKQYPALLSVALFFASMLLYSQAATAKALIPTVIVALGLSA 423

Query: 364 ----SPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLGVA 419
                    VASFAAVS LF+LPTYPTL+ AVQMDDTGTTRIGK+VFNHPFFIPG L +A
Sbjct: 424 TNNGDAYILVASFAAVSALFVLPTYPTLLGAVQMDDTGTTRIGKYVFNHPFFIPGVLAIA 483

Query: 420 LAVCFGFVLGSFML 433
            +V FGFVL   ML
Sbjct: 484 FSVTFGFVLAPMML 497


>UniRef50_C9R1M8 Anaerobic C4-dicarboxylate membrane transporter n=9
           Tax=Proteobacteria RepID=C9R1M8_AGGAD
          Length = 440

 Score =  453 bits (1166), Expect = e-126,   Method: Composition-based stats.
 Identities = 185/439 (42%), Positives = 267/439 (60%), Gaps = 8/439 (1%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVL-AAIGVKPGNIPFDVISIIMAVIAA 59
           M + +  IVLL I +GAR+GGIG+G  GGLG+ +L    G+KP  +P DV+ +IMAV+AA
Sbjct: 4   MFLFQFAIVLLCILIGARVGGIGLGVFGGLGLTILSFGFGLKPAGLPIDVMFMIMAVVAA 63

Query: 60  ISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVA 119
            +AMQ AGGLDY++     +LRRNPK IT +AP VT+  T+ AGTG+++ + LPVIAEV+
Sbjct: 64  AAAMQAAGGLDYMIKIATNILRRNPKDITFMAPAVTWTFTLLAGTGHVAYSVLPVIAEVS 123

Query: 120 KEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAV 179
           ++ G++P RPLS AV+++Q AI ASPI+AAVV + + +E  GI    +L V IPST++ +
Sbjct: 124 RQNGIRPERPLSMAVIASQFAIVASPIAAAVVAVVAYLEPQGIHLGDVLIVTIPSTIIGL 183

Query: 180 LVMSFLVTMLFNSKLSDDPIYRKRLEEGLV-----ELRGEKQIEIKSGAKTSVWLFLLGV 234
            +    V  +   +L DDP Y++RL +             K++EI   AK SV LFL G 
Sbjct: 184 FLACIFVNKM-GKELKDDPEYQRRLNDPKYAEAFNSTTSSKELEISKTAKISVSLFLFGA 242

Query: 235 VGVVIYAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGM 294
           + VV+   + S          M   +AI IIML++  L  + CK D   I   S F AGM
Sbjct: 243 LLVVLMGAMPSLRPVFDG-KPMGMAHAIEIIMLTIGALIILTCKPDGTEITKGSVFHAGM 301

Query: 295 SACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKAL 354
            A I I G+AWLGDT +  +++ +K     +++  PW  A+  F  S L+ SQ AT   L
Sbjct: 302 RAVIAIFGIAWLGDTLMQAHLEEVKGMVRGLVETAPWTFAIALFILSVLVNSQGATVATL 361

Query: 355 MPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPG 414
            P+ +AL + P   V  F AV+G F +P Y  ++A++  D TGTTRIGK++FNH F +PG
Sbjct: 362 FPLGIALGIPPAVLVGVFVAVNGYFFIPNYGPIIASIDFDTTGTTRIGKYIFNHSFMLPG 421

Query: 415 TLGVALAVCFGFVLGSFML 433
            L +A ++  G +  +  L
Sbjct: 422 LLSMAFSLALGLLFANIFL 440


>UniRef50_P44855 Anaerobic C4-dicarboxylate transporter dcuB n=162 Tax=Bacteria
           RepID=DCUB_HAEIN
          Length = 440

 Score =  448 bits (1153), Expect = e-124,   Method: Composition-based stats.
 Identities = 183/439 (41%), Positives = 264/439 (60%), Gaps = 8/439 (1%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVL-AAIGVKPGNIPFDVISIIMAVIAA 59
           M +++  IVLL IF+GAR+GGIG+G  GGLG+ +L    G+KP  +P DV+ +IMAV+AA
Sbjct: 4   MFLLQFAIVLLCIFVGARVGGIGLGVFGGLGLAILSFGFGLKPAGLPIDVMFMIMAVVAA 63

Query: 60  ISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVA 119
            +AMQ AGGLDY++    K+LRRNPK+IT +AP VT+  T+ AGTG+++ + LPVIAEV+
Sbjct: 64  AAAMQAAGGLDYMIKIATKILRRNPKHITFIAPAVTWLFTLLAGTGHVAYSVLPVIAEVS 123

Query: 120 KEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAV 179
           ++ G++P RP+S AV+++Q AI ASPI+AAVV + + +E  GI    +L V IPST+L +
Sbjct: 124 RQNGIRPERPMSMAVIASQFAIVASPIAAAVVAVVAYLEPQGIHLGDVLMVTIPSTILGL 183

Query: 180 LVMSFLVTMLFNSKLSDDPIYRKRLEEGLV-----ELRGEKQIEIKSGAKTSVWLFLLGV 234
            +    V  +   +L DDP Y++RL +             K++E+   AK SV LFL G 
Sbjct: 184 FLACLFVNKM-GKELKDDPEYQRRLNDPKYADIFASTTSVKEVEVSKTAKISVSLFLFGA 242

Query: 235 VGVVIYAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGM 294
           + VV+     S          M   + I IIMLS+  L  + CK D   I   S F AGM
Sbjct: 243 LLVVLMGAAPSIRPVFDG-KPMGMAHTIEIIMLSIGALIILTCKPDGTAITKGSVFHAGM 301

Query: 295 SACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKAL 354
            A I I G+AWLGDT +  +I  +K+    +++  PW  A   F  S L+ SQ AT   L
Sbjct: 302 RAVIAIFGIAWLGDTLMQAHITEVKEMVKGLVETAPWAFAFALFVLSVLVNSQGATVATL 361

Query: 355 MPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPG 414
            P+ +AL +     +  F AV+G F +P Y  ++A++  D TGTT+IGK++ NH F +PG
Sbjct: 362 FPLGIALGIPAPVLIGVFVAVNGYFFIPNYGPIIASLDFDTTGTTKIGKYILNHSFMLPG 421

Query: 415 TLGVALAVCFGFVLGSFML 433
            L +   +  G  L   +L
Sbjct: 422 LLSMFFCLLIGLGLSHVIL 440


>UniRef50_B4CX44 Anaerobic c4-dicarboxylate antiporter, Dcu family n=1
           Tax=Chthoniobacter flavus Ellin428 RepID=B4CX44_9BACT
          Length = 444

 Score =  448 bits (1153), Expect = e-124,   Method: Composition-based stats.
 Identities = 183/439 (41%), Positives = 271/439 (61%), Gaps = 9/439 (2%)

Query: 2   LVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLA-AIGVKPGNIPFDVISIIMAVIAAI 60
           L++E +++L A+ +GAR GG+G+G  G +G+LVL    G+ P +IP +V+ I++ VI A 
Sbjct: 5   LILEFLVILGALAMGARAGGVGLGLWGAVGLLVLVLGFGIAPASIPGEVLLIVLTVIMAA 64

Query: 61  SAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAK 120
           SAM+VAGG+D+LV   EK++R NPK +TI+AP+VTY  T  AGTG+I    LPVI EVA 
Sbjct: 65  SAMEVAGGIDFLVRVAEKIIRSNPKQVTIVAPLVTYGFTFAAGTGHIVYPLLPVIYEVAY 124

Query: 121 EQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAVL 180
           E G++P RP++ A +++Q AITASP+SAA   M  ++  H I  + +L + +PSTLLAVL
Sbjct: 125 ENGIRPERPMAVATIASQQAITASPVSAATAAMIGLLAAHHIGLVQILIICVPSTLLAVL 184

Query: 181 VMSFLVTMLFNSKLSDDPIYRKRLEEGLVELRGEKQIEIKS----GAKTSVWLFLLGVVG 236
           + +F V +    +L DDP Y++ L  G +   G+           GAK+S ++FL GV  
Sbjct: 185 ISAF-VQLHVGKELKDDPEYQRLLASGKLHPPGKTSGATPPPLKNGAKSSAFIFLAGVSL 243

Query: 237 VVIYAIINSPS---MGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAG 293
           VV+  I            +  +++   AI I+ML+VA +   + K   + +    T ++G
Sbjct: 244 VVLAGIFPVLRTVDASSAKPTVLSMPIAIAIVMLAVAAVILTVTKAPVEEVPKCKTCQSG 303

Query: 294 MSACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKA 353
           ++A I ILG+AWLGDTF++ N + I      + +  PW  A+  F AS LLYSQAAT +A
Sbjct: 304 VTAIIGILGLAWLGDTFINANRETIIGGLSSMAKAAPWTFAIGLFLASMLLYSQAATTRA 363

Query: 354 LMPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIP 413
           LMP+ L+L +     +  F AV+G F +P Y TL+AA+Q D T TT IGK++ NH F +P
Sbjct: 364 LMPLGLSLGIPAPFLIGMFPAVNGYFFIPNYGTLIAAMQFDRTHTTHIGKYLLNHSFMLP 423

Query: 414 GTLGVALAVCFGFVLGSFM 432
           G +     V  G ++ SFM
Sbjct: 424 GLVSTIGGVSIGLLIASFM 442


>UniRef50_Q5HVA4 Anaerobic C4-dicarboxylate membrane transporter DcuB n=25
           Tax=Proteobacteria RepID=Q5HVA4_CAMJR
          Length = 474

 Score =  439 bits (1130), Expect = e-122,   Method: Composition-based stats.
 Identities = 151/457 (33%), Positives = 257/457 (56%), Gaps = 30/457 (6%)

Query: 2   LVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAA-IGVKPGNIPFDVISIIMAVIAAI 60
             +++IIVL+ +F GA+ GGI +G  GG+G+L+L     +KPG    DV+  I+AV+ A 
Sbjct: 13  FAIQIIIVLICLFYGAKKGGIALGLLGGIGILMLVFTFHIKPGKPAIDVMLTILAVVVAS 72

Query: 61  SAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAK 120
           + +Q +GGLD ++   E++LRRNPK++TILAP VT FLTI  GTG++    +P+I ++A 
Sbjct: 73  ATLQASGGLDVMLQIAERILRRNPKFLTILAPFVTCFLTILCGTGHVVYTIMPIIYDIAI 132

Query: 121 EQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVM--EGHGI----SYLHLLSVVIPS 174
           + G++P RP++ A +S+Q+ I ASP+S AVV +++++    H +     Y++LL + IPS
Sbjct: 133 KNGIRPERPMAAASISSQMGIIASPVSVAVVSLTALLLNANHKLAGFDGYINLLQITIPS 192

Query: 175 TLLAVLVMSFLVTMLFNSKLSDDPIYRKRLEEGLVELR------GEKQIEIKSGAKTSVW 228
           TL  VL +  + +      L  D +++++L++   +            +++      ++W
Sbjct: 193 TLFGVLCVG-IFSWFRGKDLDKDEVFQEKLKDPEFKKYVYGDSKTLLGVKLPKSNWVAMW 251

Query: 229 LFLLGVVGVVIYAIINSPSMGL----------------VEKPLMNTTNAILIIMLSVATL 272
           +FL  +  V +  + +                       +  +++  + I + ML   +L
Sbjct: 252 IFLGAIALVALLGVFDFLRPNWGQVVKNGIPQVDALGNPKMDVLSMVSVIQMFMLLAGSL 311

Query: 273 TTVICKVDTDNILNSSTFKAGMSACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWL 332
             +  K D   I ++  FK+GM A + + G++W+ DT  + +   +K   G++++ HPW 
Sbjct: 312 IIIFTKTDAKKIGSNEIFKSGMIALVAVFGISWMADTMFAVHTPMMKAALGDIVKEHPWT 371

Query: 333 LAVIFFFASALLYSQAATAKALMPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQ 392
            AV+    S  + SQAA   A +P+AL + V P   VA  AA  G +ILPTYP+ +A +Q
Sbjct: 372 YAVMLLLISKFVNSQAAAISAFVPLALGIGVEPGAIVAFAAACYGYYILPTYPSDLATIQ 431

Query: 393 MDDTGTTRIGKFVFNHPFFIPGTLGVALAVCFGFVLG 429
            D +GTT IGKFV NH F +PG +GV  +   G+ + 
Sbjct: 432 FDRSGTTHIGKFVINHSFILPGLIGVITSCIAGYFIA 468


>UniRef50_C8N6Y6 Anaerobic C4-dicarboxylate transporter DcuB n=1 Tax=Cardiobacterium
           hominis ATCC 15826 RepID=C8N6Y6_9GAMM
          Length = 479

 Score =  438 bits (1128), Expect = e-121,   Method: Composition-based stats.
 Identities = 174/457 (38%), Positives = 267/457 (58%), Gaps = 26/457 (5%)

Query: 2   LVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAA-IGVKPGNIPFDVISIIMAVIAAI 60
            +++  IVLL I LGAR+GGIG+G  GGLG+ +L    G++P + P DV+ +IMAV++A 
Sbjct: 24  FLIQFAIVLLCILLGARVGGIGLGVFGGLGLAILTFGFGLQPTSPPIDVMLMIMAVVSAA 83

Query: 61  SAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAK 120
           +AM+ +GGLD ++    ++LR+NPKYIT +AP VTY  TIFAGTG+++ + LPVIAEV++
Sbjct: 84  AAMEASGGLDLMIRVATRILRKNPKYITFMAPAVTYIFTIFAGTGHVAYSVLPVIAEVSR 143

Query: 121 EQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAVL 180
             G++P RPLS AV+++Q +I ASPI+AAV   +S +  + IS   +L V IPST L + 
Sbjct: 144 RSGIRPERPLSMAVIASQFSIVASPIAAAVTSAASYLTPYHISIPQILMVTIPSTTLGIA 203

Query: 181 VMSFLVTMLFNSKLSDDPIYRKRLEEGLVEL--------RGEKQIEIKSGAKTSVWLFLL 232
           +    V  +   +L DDP Y++RL++ + +          G + +  +  A+TS+ +F+ 
Sbjct: 204 IACVFVNKM-GKELKDDPEYQRRLKDPVYQEIYAAQESSSGTETVINEKSARTSLKIFIS 262

Query: 233 GVVGVVIYAIINSP------------SMGLVEKP----LMNTTNAILIIMLSVATLTTVI 276
             + VVI   ++                   +      L+N  + I I+ML+ A    + 
Sbjct: 263 AAILVVILGSLDKLAKYLPAELMAHLRPSFPDAKGDMKLLNMPHVIEIVMLTAAAFIIMF 322

Query: 277 CKVDTDNILNSSTFKAGMSACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVI 336
           CK D   I   S F AGM A I I G+AWLGDT  + ++D +K     +++  PW  A  
Sbjct: 323 CKPDGTAITRGSVFHAGMRAVIAIFGIAWLGDTLFNAHLDELKTLVSGLVETAPWTFAFA 382

Query: 337 FFFASALLYSQAATAKALMPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDT 396
            F  S L+ SQ AT   L P+ ++L + P   V +F AV+G F +P Y  ++A++  D T
Sbjct: 383 LFAFSVLVNSQGATVATLFPLGVSLGIPPEIMVGTFVAVNGYFFIPNYGPIIASIDFDTT 442

Query: 397 GTTRIGKFVFNHPFFIPGTLGVALAVCFGFVLGSFML 433
           GTTRIG+++ NH F IPG L +A ++  G      +L
Sbjct: 443 GTTRIGRYILNHSFMIPGLLSMAFSLVLGLAFAKMLL 479


>UniRef50_C6CN04 Anaerobic c4-dicarboxylate antiporter, Dcu family n=22 Tax=Bacteria
           RepID=C6CN04_DICZE
          Length = 453

 Score =  438 bits (1126), Expect = e-121,   Method: Composition-based stats.
 Identities = 153/442 (34%), Positives = 260/442 (58%), Gaps = 14/442 (3%)

Query: 2   LVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAA-IGVKPGNIPFDVISIIMAVIAAI 60
            +++L+IVL+ +F GAR GGI +G  GG+G+++L     ++PG  P DV+ +I++V+AA 
Sbjct: 10  FIIQLVIVLICLFYGARKGGIALGLLGGIGLVILVFIFKLEPGKPPVDVMLVIISVVAAS 69

Query: 61  SAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAK 120
           + +Q +GGLD ++   EK+LRRNPKY++I+AP VT  LT+  GTG++    LP+I +VA 
Sbjct: 70  ATLQASGGLDVMLQVAEKMLRRNPKYVSIIAPFVTCILTMLCGTGHVVYTILPIIYDVAI 129

Query: 121 EQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVM-----EGHGISYLHLLSVVIPST 175
           +  ++P RP++ + + AQ+ I ASP+S AVV + +++      G  + +L LL++ IPST
Sbjct: 130 KNNIRPERPMAASSIGAQMGIIASPVSVAVVSLVAMLGKFTFHGKHLEFLDLLAITIPST 189

Query: 176 LLAVLVMSFLVTMLFNSKLSDDPIYRK--RLEEGLVELRGEK----QIEIKSGAKTSVWL 229
           LL +L +  + +      L  DP ++K   + E    + G+       ++      ++W+
Sbjct: 190 LLGILAIG-IFSWFRGKDLDKDPDFQKFISVPENREYVYGDTATLLDRKLPRSNWVAMWI 248

Query: 230 FLLGVVGVVIYAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSST 289
           FL  +  V +   + S          ++    I + ML    +  +  K +  +I  +  
Sbjct: 249 FLATIAAVALLGAVESLRPTF-GGKPLSMVLVIQMFMLLSGAIIIIATKTNPGSISKNEV 307

Query: 290 FKAGMSACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAA 349
           F++GM A + + G+AW+ +T    ++  IK+T G +++ +PW  A++    S  + SQAA
Sbjct: 308 FRSGMIAIVAVYGIAWMAETMFGAHLAEIKETLGTLVKDYPWAYALVLLLVSKFVNSQAA 367

Query: 350 TAKALMPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHP 409
              A++P+ALA+ V P   VAS  A  G +ILPTYP+ +AA+Q D +GTT IG+FV NH 
Sbjct: 368 ALAAIVPVALAIGVDPAYIVASAPACYGYYILPTYPSDLAAIQFDRSGTTHIGRFVINHS 427

Query: 410 FFIPGTLGVALAVCFGFVLGSF 431
           F +PG +GV+ +  FG+V  + 
Sbjct: 428 FILPGLIGVSTSCVFGWVFAAM 449


>UniRef50_Q5E4K5 Anaerobic C4-dicarboxylate transporter n=16 Tax=Gammaproteobacteria
           RepID=Q5E4K5_VIBF1
          Length = 433

 Score =  431 bits (1108), Expect = e-119,   Method: Composition-based stats.
 Identities = 186/433 (42%), Positives = 289/433 (66%), Gaps = 3/433 (0%)

Query: 2   LVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLA-AIGVKPGNIPFDVISIIMAVIAAI 60
           +++E+ +VL+ I+ G ++GG+G+G AGG G+ VL   +G++P     DVI IIM+V+ A 
Sbjct: 3   VIIEISVVLICIYWGLKMGGLGVGLAGGFGLAVLTLGLGLEPSAPAIDVILIIMSVVTAA 62

Query: 61  SAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAK 120
           S MQ AGG+++LVH    L+RR+PKYI ILAPI+T+ +TI AGTG    +TLPVI+EVAK
Sbjct: 63  STMQAAGGMEWLVHHAGNLMRRHPKYINILAPIITWCMTIMAGTGYTVFSTLPVISEVAK 122

Query: 121 EQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAVL 180
           E G +P RPLS AVV++Q+AI+ SPISAA+  M S+ME  G+S+L ++++ +P++ +A +
Sbjct: 123 EIGERPSRPLSAAVVASQVAISGSPISAAMAAMISIMEPAGVSFLQIMAICLPASFIAAM 182

Query: 181 VMSFLVTMLFNSKLSDDPIYRKRLEEGLVELRGEKQIEIKSGAKTSVWLFLLGVVGVVIY 240
           V +F+ +     +L DD +Y++  +E    +      +I   AK SV+LF L    +V+Y
Sbjct: 183 VAAFIASRQ-GCELKDDVVYQQIQKENKQHVTSMT-KDIDPKAKYSVFLFALATCAIVLY 240

Query: 241 AIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSACICI 300
           A I S         +M T + I++ M + A L   +C +  D I+ ++TF++GMS+   I
Sbjct: 241 AAIPSLRPAFPSGDIMTTRDIIIVSMFAAACLMVPMCNIHPDRIIKTTTFRSGMSSVAVI 300

Query: 301 LGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPMALA 360
           LG+  +G T V+ ++  IK+ AG ++  +P LL+++ F    LL SQ AT   ++P+AL+
Sbjct: 301 LGIVTMGSTVVNAHLPEIKEFAGSLLHSYPMLLSLVLFGTCTLLMSQGATTPLIVPLALS 360

Query: 361 LNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLGVAL 420
           LNV     +ASF AV+G+F+LPTYPT +AA++ D TG+TR+GK +F+HPF +PG  GV +
Sbjct: 361 LNVPHWAILASFVAVTGVFVLPTYPTSLAAIEFDSTGSTRMGKNIFDHPFMLPGLTGVIV 420

Query: 421 AVCFGFVLGSFML 433
           A+ FGF+L   +L
Sbjct: 421 AIGFGFLLAPAVL 433


>UniRef50_Q9ZLC0 Anaerobic C4-dicarboxylate transporter dcuA n=226 Tax=Bacteria
           RepID=DCUA_HELPJ
          Length = 443

 Score =  430 bits (1105), Expect = e-119,   Method: Composition-based stats.
 Identities = 236/440 (53%), Positives = 314/440 (71%), Gaps = 10/440 (2%)

Query: 3   VVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLA-AIGVKPGNIPFDVISIIMAVIAAIS 61
             ++I++L ++FLGARLGG+G+G+AGGLGVL+L   +G+ PG IPFDVI IIMAVI+AIS
Sbjct: 5   FFQIIVLLFSLFLGARLGGLGVGYAGGLGVLILCLFLGLNPGKIPFDVILIIMAVISAIS 64

Query: 62  AMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAKE 121
           AMQ AGGLDYLV   EK+LR++PK I  LAP V YFLTI AGTG+   + +PVI EV++ 
Sbjct: 65  AMQKAGGLDYLVQIAEKILRKHPKQINYLAPSVAYFLTILAGTGHTVFSLIPVIVEVSQS 124

Query: 122 QGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAVLV 181
           Q +KP  PLS AVVS+Q+AITASP+SAAVV+MS ++E  G  YL LL V IP+T LA ++
Sbjct: 125 QNIKPKAPLSLAVVSSQVAITASPVSAAVVFMSGILEPLGADYLTLLMVWIPTTFLACML 184

Query: 182 MSFLVTMLFNSKLSDDPIYRKRLEEGLVELR-GEKQIEIKSGAKTSVWLFLLGVVGVVIY 240
            +F++    + KL  DP Y +RL+ G +     +K+ E    AK S+W+F+ GVV +V Y
Sbjct: 185 TAFVMGFT-DLKLDSDPNYLERLKAGKISPPMMKKEKETSKSAKLSLWIFIGGVVAIVFY 243

Query: 241 AIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSACICI 300
           A   S ++ L+   ++    AI+  MLSVATL  + CK++ + I +SS FK+GM AC+C+
Sbjct: 244 ASAISKNIALISPVILGRDYAIVSFMLSVATLIAIFCKINANEIAHSSVFKSGMQACVCV 303

Query: 301 LGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPMAL- 359
           LGVAWLGDTFVSN+ID IK  A  +I  +P+LLAV  F AS LLYSQAAT+KAL+P  + 
Sbjct: 304 LGVAWLGDTFVSNHIDEIKRYASFLIADYPFLLAVALFLASMLLYSQAATSKALIPSVIT 363

Query: 360 ALNVSP------LTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIP 413
           AL +S          VASFA+VS LF+LPTYPTL+ A+ MD TGTT++G++VF+H F IP
Sbjct: 364 ALGISANHTEHLYIIVASFASVSALFVLPTYPTLLGAIAMDHTGTTKMGRYVFDHAFLIP 423

Query: 414 GTLGVALAVCFGFVLGSFML 433
           G L V L+V  GFV+   +L
Sbjct: 424 GVLVVFLSVALGFVVAPLVL 443


>UniRef50_P0ABP1 Anaerobic C4-dicarboxylate transporter dcuB n=130 Tax=Bacteria
           RepID=DCUB_ECO57
          Length = 446

 Score =  427 bits (1099), Expect = e-118,   Method: Composition-based stats.
 Identities = 136/407 (33%), Positives = 233/407 (57%), Gaps = 13/407 (3%)

Query: 36  AAIGVKPGNIPFDVISIIMAVIAAISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVT 95
               ++PG  P DV+ +I+AV+AA + +Q +GGLD ++   EKLLRRNPKY++I+AP VT
Sbjct: 38  FVFHLQPGKPPVDVMLVIIAVVAASATLQASGGLDVMLQIAEKLLRRNPKYVSIVAPFVT 97

Query: 96  YFLTIFAGTGNISLATLPVIAEVAKEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSS 155
             LTI  GTG++    LP+I +VA +  ++P RP++ + + AQ+ I ASP+S AVV + +
Sbjct: 98  CTLTILCGTGHVVYTILPIIYDVAIKNNIRPERPMAASSIGAQMGIIASPVSVAVVSLVA 157

Query: 156 VM-----EGHGISYLHLLSVVIPSTLLAVLVMSFLVTMLFNSKLSDDPIYRK--RLEEGL 208
           ++     +G  + +L LL++ IPSTL+ +L +  + +      L  D  ++K   + E  
Sbjct: 158 MLGNVTFDGRHLEFLDLLAITIPSTLIGILAIG-IFSWFRGKDLDKDEEFQKFISVPENR 216

Query: 209 VELRGEK----QIEIKSGAKTSVWLFLLGVVGVVIYAIINSPSMGLVEKPLMNTTNAILI 264
             + G+       ++      ++W+FL  +  V +    +           ++    I +
Sbjct: 217 EYVYGDTATLLDKKLPKSNWLAMWIFLGAIAVVALLGADSDLRPSF-GGKPLSMVLVIQM 275

Query: 265 IMLSVATLTTVICKVDTDNILNSSTFKAGMSACICILGVAWLGDTFVSNNIDWIKDTAGE 324
            ML    L  ++ K +  +I  +  F++GM A + + G+AW+ +T    ++  I+   GE
Sbjct: 276 FMLLTGALIIILTKTNPASISKNEVFRSGMIAIVAVYGIAWMAETMFGAHMSEIQGVLGE 335

Query: 325 VIQGHPWLLAVIFFFASALLYSQAATAKALMPMALALNVSPLTAVASFAAVSGLFILPTY 384
           +++ +PW  A++    S  + SQAA   A++P+ALA+ V P   VAS  A  G +ILPTY
Sbjct: 336 MVKEYPWAYAIVLLLVSKFVNSQAAALAAIVPVALAIGVDPAYIVASAPACYGYYILPTY 395

Query: 385 PTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLGVALAVCFGFVLGSF 431
           P+ +AA+Q D +GTT IG+FV NH F +PG +GV+++  FG++  + 
Sbjct: 396 PSDLAAIQFDRSGTTHIGRFVINHSFILPGLIGVSVSCVFGWIFAAM 442


>UniRef50_B4UMD4 Anaerobic c4-dicarboxylate antiporter, Dcu family n=20
           Tax=Proteobacteria RepID=B4UMD4_ANASK
          Length = 447

 Score =  426 bits (1095), Expect = e-118,   Method: Composition-based stats.
 Identities = 163/446 (36%), Positives = 236/446 (52%), Gaps = 14/446 (3%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAA-IGVKPGNIPFDVISIIMAVIAA 59
           M  ++  +VL AI LG R GG+ +G  GGLGV VL       P   P  V+ II+AV+  
Sbjct: 3   MFWIQFALVLGAILLGIRRGGVALGMIGGLGVAVLVFLFRAAPSEPPIAVMLIILAVVTT 62

Query: 60  ISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVA 119
            + +QVAGGLDYLV   EKLLR +PKY+TILAP  T+FLT+  GTG+   A LPVIA+VA
Sbjct: 63  SATLQVAGGLDYLVQLAEKLLRAHPKYVTILAPFCTFFLTMAVGTGHAVYALLPVIADVA 122

Query: 120 KEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSV--MEGHGISYLHLLSVVIPSTLL 177
            +   +P RP++ + V++Q+ ITASP++AAV    +     G  +S   +L + IP+ ++
Sbjct: 123 LKTKTRPERPMAISSVASQMGITASPVAAAVTTFLAFSAKAGQPLSLYDILKITIPAGVV 182

Query: 178 AVLVMSFLVTMLFNSKLSDDPIYRKRLEEGLVELRGE-----KQIEIKSGAKTSVWLFLL 232
            VL  + L +M     L  DP + K+LE+       +        ++   A+ SV LF  
Sbjct: 183 GVLAAA-LWSMNRGRDLYSDPEFLKKLEDPEFRKSLDVSVTTLDKQLPRAARLSVLLFFT 241

Query: 233 GVVGVVIYAIINS-----PSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNS 287
           GV  +V+ A+            +     +  T  + I+ML+         KV    +  S
Sbjct: 242 GVATIVVLALDQDFLHLGLIPLVNGGKPVAMTTVVQIVMLAFGAFILFTAKVKAAEVARS 301

Query: 288 STFKAGMSACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQ 347
           S F AGM A + I G+AW+ DTFV+ N  ++ +    ++Q  PW  AV  F  SA + SQ
Sbjct: 302 SVFTAGMIAVVSIFGIAWMSDTFVTANKPFLIEKIQAMVQVAPWTFAVAMFCVSAFVKSQ 361

Query: 348 AATAKALMPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFN 407
           AAT   ++P  LAL +     +    A    F    YP+ +AA+ MD TGTT IGK++ N
Sbjct: 362 AATLTIMLPFGLALGLPATLLLGLMPASYAYFFFCFYPSDLAAINMDRTGTTHIGKYLLN 421

Query: 408 HPFFIPGTLGVALAVCFGFVLGSFML 433
           H F IPG +GV  +    + L     
Sbjct: 422 HSFMIPGFIGVGTSTVVAYALSRLAF 447


>UniRef50_Q7NRZ2 Anaerobic C4-dicarboxylate membrane transporter protein n=1
           Tax=Chromobacterium violaceum RepID=Q7NRZ2_CHRVO
          Length = 436

 Score =  423 bits (1089), Expect = e-117,   Method: Composition-based stats.
 Identities = 173/433 (39%), Positives = 274/433 (63%), Gaps = 6/433 (1%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAA-IGVKPGNIPFDVISIIMAVIAA 59
           M+ ++L++VL  IFLG R+GGIG+G  GG G+ +L    G+KPG+ P DVI II++VI A
Sbjct: 1   MVYLQLVVVLGLIFLGVRMGGIGLGVTGGAGLFILTFVFGLKPGHAPIDVILIIISVITA 60

Query: 60  ISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVA 119
            +A+Q A GLDY+V    +LLRRNP++I +LAP+V +  T  AGTG I+LA +P++ EVA
Sbjct: 61  SAALQSARGLDYMVGVAARLLRRNPRHIVLLAPLVGWLSTFLAGTGFIALALMPIVVEVA 120

Query: 120 KEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAV 179
           ++ G++P RPL+   V++Q AI A P+SAA V +++V+  HG++   ++ + IP+TLL  
Sbjct: 121 EKTGIRPERPLAGLTVASQNAIVACPVSAATVALATVLAPHGVALTDIIMISIPATLLGA 180

Query: 180 LVMSFLVTMLFNSKLSDDPIYRKRLEEGLV-ELRGEKQIEIKSGAKTSVWLFLLGVVGVV 238
           L     V + +  +L+DDP+YR+RL +G +   + + +  +   A  SV+ FLL V  +V
Sbjct: 181 L-AGGAVMLRYGCELADDPVYRQRLADGGIRRPQTDAEEALPRTAAWSVYGFLLTVALIV 239

Query: 239 IYAIINSPSMGLVEKP---LMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMS 295
           + A +               +   + I + ML  + L  ++CK D   +++ S F++G  
Sbjct: 240 LLAAMPQLRPAWPGAKGMEPVAMVDVIQMCMLGYSALAVLVCKADLQGMVSGSMFRSGAV 299

Query: 296 ACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALM 355
           A + ILG AW+ DTF+  N+   K     +I+  PWL A   F  + +L+SQ AT K +M
Sbjct: 300 AAVTILGAAWMSDTFIQANLPLFKHNIVSIIESAPWLFAFAVFTMAVILFSQGATTKVMM 359

Query: 356 PMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGT 415
           P+ ++L ++    +A + AV G+++LP+YP+L+AAV+MD TGTTRIG++VFNH F +PG 
Sbjct: 360 PLGVSLGIASPVLIAIYPAVVGVYVLPSYPSLIAAVEMDYTGTTRIGRWVFNHSFILPGL 419

Query: 416 LGVALAVCFGFVL 428
              A+++  GF L
Sbjct: 420 ASTAVSIAAGFAL 432


>UniRef50_B4TYZ8 Anaerobic C4-dicarboxylate transporter DcuA n=30 Tax=Bacteria
           RepID=B4TYZ8_SALSV
          Length = 439

 Score =  423 bits (1088), Expect = e-117,   Method: Composition-based stats.
 Identities = 180/439 (41%), Positives = 276/439 (62%), Gaps = 7/439 (1%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAA-IGVKPGNIPFDVISIIMAVIAA 59
           M   EL  +L+A+ +GAR+GG+ +G  GGLGV V+    G+ P   P DVI II++V+ A
Sbjct: 1   MFWTELCFILVALMIGARIGGVFLGMVGGLGVGVMVFIFGLTPSTPPIDVILIILSVVLA 60

Query: 60  ISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVA 119
            +++Q +GGLD LV   EK+LRR+P+YIT+LAP + Y  T  +GTG++  + LPVI+EVA
Sbjct: 61  AASLQASGGLDLLVKLAEKILRRHPRYITLLAPFICYIFTFMSGTGHVVYSLLPVISEVA 120

Query: 120 KEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAV 179
           ++ G++P RPLS +V+++Q AITASPISAA+  M  +M   G+S   ++ + +P+TL+ V
Sbjct: 121 RDSGIRPERPLSISVIASQQAITASPISAAMAAMIGLMAPLGVSISTIMMICVPATLIGV 180

Query: 180 LVMSFLVTMLFNSKLSDDPIYRKRLEEGLVEL--RGEKQIEIKSGAKTSVWLFLLGVVGV 237
             M  + T     +L DDP Y++RL EGL++   +  K   + S AK SV LFL   + +
Sbjct: 181 -AMGAIATFNKGKELKDDPEYQRRLAEGLIKPAQKESKNTVVTSRAKLSVALFLTSAIVI 239

Query: 238 VIYAIINSPSMGLVEKP---LMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGM 294
           V+  +I +    +        ++ + AI I MLS A L  ++C+   D I++ + F+AG 
Sbjct: 240 VLLGLIPALRPMVETAKGLQPLSMSAAIQITMLSFACLIVLLCRPQVDQIISGTVFRAGA 299

Query: 295 SACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKAL 354
            A +C  G+AW+ +TFV+ +I  IK     ++Q H WL+A++ FF SA++ SQAAT   L
Sbjct: 300 LAIVCAFGLAWMSETFVNGHIALIKAEVQTLLQQHTWLIAIMMFFVSAMVSSQAATTLIL 359

Query: 355 MPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPG 414
           +P+ LAL +     + S+ AV+G F +P     +AA+  DDTGTTRIGK+V NH F  PG
Sbjct: 360 LPLGLALGLPAYALIGSWPAVNGYFFIPVAGQCLAALAFDDTGTTRIGKYVLNHSFMRPG 419

Query: 415 TLGVALAVCFGFVLGSFML 433
            + V ++V  G ++G  +L
Sbjct: 420 LVNVIVSVIVGLLIGKMVL 438


>UniRef50_D1P157 Anaerobic C4-dicarboxylate transporter DcuB n=2 Tax=Providencia
           RepID=D1P157_9ENTR
          Length = 443

 Score =  422 bits (1085), Expect = e-116,   Method: Composition-based stats.
 Identities = 200/434 (46%), Positives = 294/434 (67%), Gaps = 2/434 (0%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLA-AIGVKPGNIPFDVISIIMAVIAA 59
           M+ +E+I+VL AIF G R+GGIGIG  GGLG+ +L    G+  G+ P DVI IIM V+ A
Sbjct: 11  MVFLEIIVVLGAIFFGIRMGGIGIGLCGGLGLAILTIGFGLPIGSPPVDVILIIMTVVVA 70

Query: 60  ISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVA 119
            SA+Q AGG+DYLV      +R+NPKYI I+API T+ +TI AGTG I  + LPVIAE+A
Sbjct: 71  ASALQAAGGMDYLVRLAGTFMRKNPKYINIIAPITTWVMTIMAGTGFIVFSMLPVIAEIA 130

Query: 120 KEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAV 179
           K+ GV+P R L+ +VV++QIAI+ SPISAA+  M ++MEG+G++++ ++SV +P++ +A 
Sbjct: 131 KDSGVRPSRTLAGSVVASQIAISGSPISAAMAAMLTIMEGNGVTFITVMSVCLPASFVAA 190

Query: 180 LVMSFLVTMLFNSKLSDDPIYRKRLEEGLVELRGEKQIEIKSGAKTSVWLFLLGVVGVVI 239
           +V +F+ +     +L DD +Y  RL++GL+    EK+ E     K SV LF++  +G+VI
Sbjct: 191 MVAAFIASRQ-GCELEDDEVYLDRLQKGLIHKYEEKKGESTPKEKFSVILFIIATIGIVI 249

Query: 240 YAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSACIC 299
            A       G      M T + I+I MLS A L  V CK   ++I+ +STF++GMS+   
Sbjct: 250 LAAFPQLRPGFDIGKPMGTRDIIIICMLSAACLMVVFCKTSPNSIVLASTFRSGMSSLAV 309

Query: 300 ILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPMAL 359
           ILG+  LG TFV  ++  IK+ AG V+  +P LL+++ FF  ALLYSQ AT   ++P+A+
Sbjct: 310 ILGIVTLGTTFVDAHMVQIKEIAGNVLSSYPILLSLVLFFTCALLYSQGATTPLIIPLAI 369

Query: 360 ALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLGVA 419
           AL+V     +ASF AV+G+F+LPTYPT +AA++ D TG+TR+GK++ NHPF +PG  G+ 
Sbjct: 370 ALDVPTWAILASFVAVTGVFVLPTYPTSLAAMEFDSTGSTRVGKYILNHPFMLPGLGGII 429

Query: 420 LAVCFGFVLGSFML 433
             V FGF++   ++
Sbjct: 430 AGVAFGFIIAPMVV 443


>UniRef50_B6EGF2 Anaerobic c4-dicarboxylate transporter DcuB n=1 Tax=Aliivibrio
           salmonicida LFI1238 RepID=B6EGF2_ALISL
          Length = 444

 Score =  399 bits (1025), Expect = e-109,   Method: Composition-based stats.
 Identities = 153/442 (34%), Positives = 249/442 (56%), Gaps = 12/442 (2%)

Query: 2   LVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLA-AIGVKPGNIPFDVISIIMAVIAAI 60
             ++L +VL  I +G R GG+G+G AGGLGV +L    G++P + P  V+ II+AVIA  
Sbjct: 5   FWLQLAVVLGCIGIGGRFGGVGLGAAGGLGVCLLVLGFGLQPASPPVTVLLIIIAVIACT 64

Query: 61  SAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAK 120
           S +Q AGGLD+LV   EKLLR+ P  IT L P+++    IF GT  ++ A  PVIAEVA 
Sbjct: 65  SVLQGAGGLDFLVRIAEKLLRKKPSAITFLGPLISSMFVIFCGTSYVAFAVYPVIAEVAA 124

Query: 121 EQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAVL 180
           E  ++P RP+S AV+++ IAITASP+SAA   M + +  + +S+  +L+V +P+ L+  L
Sbjct: 125 EAKIRPERPMSMAVIASGIAITASPMSAATAGMIASLSLYDVSFFQILAVSMPAFLIGAL 184

Query: 181 VMSFLVTMLFNSKLSDDPIYRKRLEEGLVEL------RGEKQIEIKSGAKTSVWLFLLGV 234
                V      +L  DP +++R+  G  +L        E++ +  +G K SV +F LGV
Sbjct: 185 CGCAFVYK-RGLELEQDPEFQRRVASGEYQLIHEDVNSPEEEYKPSTGVKASVLVFGLGV 243

Query: 235 VGVVIYAIINSPSMGLV---EKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFK 291
             V+++    S         +  +++T   I ++ML+ A    V  KV +D   + S F+
Sbjct: 244 ATVILFGTFKSLLPSWDIDGKTVVLSTPMLIQMVMLASALFIIVFAKVPSDKFASGSVFR 303

Query: 292 AGMSACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATA 351
           +G+   + + G++W+  TF +    + + T   +++  P +  +I F  SA+++S +AT 
Sbjct: 304 SGLIGVVGVFGISWMTGTFFNAYQPFFETTFEGMVETAPMMFGLILFCFSAVIFSPSATV 363

Query: 352 KALMPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFF 411
            ALMP+  A+ + P   VA + A  G FI+P     +  +  D TGTTR+G +V NH + 
Sbjct: 364 SALMPLGAAMGIPPGLLVALYPATCGDFIVPGTGQ-IGCLSFDRTGTTRLGTYVINHSYI 422

Query: 412 IPGTLGVALAVCFGFVLGSFML 433
           +PG + V  +V  G+ +   + 
Sbjct: 423 LPGFVMVISSVTAGYFISKIVF 444


>UniRef50_C3JGC7 C4-dicarboxylate membrane transporter n=2 Tax=Rhodococcus
           erythropolis RepID=C3JGC7_RHOER
          Length = 443

 Score =  392 bits (1008), Expect = e-107,   Method: Composition-based stats.
 Identities = 138/438 (31%), Positives = 246/438 (56%), Gaps = 8/438 (1%)

Query: 2   LVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAA-IGVKPGNIPFDVISIIMAVIAAI 60
           +V+EL +VL AI +G R  G+ +G  GG GV VL    G   G+ P D + I+++V+ A 
Sbjct: 6   IVLELAVVLGAIVMGTRSSGVALGLWGGAGVAVLVFVFGEDVGSPPVDALLIVLSVVLAS 65

Query: 61  SAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAK 120
           S MQ AGG+D++V    KL+   PK IT++AP+V++  ++ AGT NI    LPVI +V+ 
Sbjct: 66  SMMQAAGGIDWMVTIAAKLIESRPKQITLIAPLVSFLFSVGAGTSNILYPLLPVIYDVSY 125

Query: 121 EQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVME--GHGISYLHLLSVVIPSTLLA 178
           + GV+P RPLS +VVS  +A+  SP+SAA+  M ++ +   +    + ++ +  P+ ++ 
Sbjct: 126 KNGVRPSRPLSLSVVSTGVALACSPVSAAMAAMVTLTDVPPYDFELIDIIKITFPAAVVG 185

Query: 179 VLVMSFLVTMLFNSKLSDDPIYRKRLEEGLVELRG---EKQIEIKSGAKTSVWLFLLGVV 235
           +++ S  V  L    L DDP  + +++ G +   G   + ++      + +  +FL GV+
Sbjct: 186 IVLSSIAVNRL-GKDLDDDPEIQAKMKSGELAGPGAASKTELVSTKTGRNAALIFLAGVL 244

Query: 236 GVVIYAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMS 295
            +VI+ +         +   M  T  I ++M  V TL  ++C+ +  ++ +S+ F+AGM 
Sbjct: 245 AIVIFGLFKGIRPEAADGTPMGMTPIIEMLMFVVGTLILLVCRPNVADVPSSTVFRAGMV 304

Query: 296 ACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALM 355
           + I + G+AWL DTF+S + + I  T G+ +   PW+ A+  F    L  SQ+   + ++
Sbjct: 305 SAIALFGLAWLTDTFISAHSELITSTVGDWVNAAPWIFALGVFLVCVLTTSQSTATRTIV 364

Query: 356 PMALALNVSPLTAVASFA-AVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPG 414
           P+ LA  ++P      +A A +G+++LPT  + +AA   D +G+T++G  + +H FF+P 
Sbjct: 365 PIGLAAGIAPGLVSGMWAGAFAGVYLLPTNGSQIAAANFDLSGSTKLGSKLVDHSFFLPT 424

Query: 415 TLGVALAVCFGFVLGSFM 432
            +     +  G + G  +
Sbjct: 425 IILAVTTIAAGALFGVVL 442


>UniRef50_B1LPU8 Anaerobic C4-dicarboxylate membrane transporter, DcuB family n=3
           Tax=Gammaproteobacteria RepID=B1LPU8_ECOSM
          Length = 438

 Score =  381 bits (980), Expect = e-104,   Method: Composition-based stats.
 Identities = 157/438 (35%), Positives = 243/438 (55%), Gaps = 8/438 (1%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLA-AIGVKPGNIPFDVISIIMAVIAA 59
           +  ++L IVL  I +G + GG+G+G  GGLGV +L    G+KP +     + II+ VI+A
Sbjct: 4   LFFIQLFIVLACIGIGGKYGGMGLGAGGGLGVAILVLGFGLKPSSPSITAMLIIICVISA 63

Query: 60  ISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVA 119
           +S +Q  GGLDYLV   E++LR+ P+ IT +API+T   T+F GT  ++ +  PVIAEVA
Sbjct: 64  VSILQAVGGLDYLVRVAERILRKKPQAITFVAPILTSVFTLFCGTTYVAFSLYPVIAEVA 123

Query: 120 KEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGH-GISYLHLLSVVIPSTLLA 178
            E  V+P R LS  V++A +A+ ASP+SAA   M +++  + GI+   +LS+ +PS  +A
Sbjct: 124 AEAKVRPERALSATVIAASVAVAASPMSAATAGMLAILHEYAGITLGQILSIALPSFFMA 183

Query: 179 VLVMSFLVTMLFNSKLSDDPIYRKRLEEGLV---ELRGEKQIEIKSGAKTSVWLFLLGVV 235
            +V SF V      +L DDP +++R+  G         +K+     GA+  V +F +GVV
Sbjct: 184 AIVTSFSVYK-RGKELEDDPEFQRRVAAGEYEFMHTEQKKEYVAAPGARKGVAIFAIGVV 242

Query: 236 GVVIYAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMS 295
            V+I                ++T   I +IML+ A L  ++ KV ++   + S F+AG+ 
Sbjct: 243 LVLILGSFTELLPSWDG-KRLSTPMVIQMIMLTAALLIMIVGKVPSNKFNSGSVFRAGLM 301

Query: 296 ACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALM 355
             + ILGV+W+  TF       + +  G ++   P L   I F  S ++ S AAT  A+M
Sbjct: 302 GVVAILGVSWMTATFFDAYQAELINVFGNLVNDAPLLFGFIVFLFSLVIMSPAATVAAIM 361

Query: 356 PMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGT 415
           P+ + L +     +A FA   G FI+P     +  V  D TGTTRIG+FV NH +  PG 
Sbjct: 362 PLGVTLGIPAPYLIAIFACTCGDFIIPG-ANQIGCVAFDRTGTTRIGRFVINHSYIRPGF 420

Query: 416 LGVALAVCFGFVLGSFML 433
           + V   V F +++   +L
Sbjct: 421 VMVISQVVFAYLIAQVIL 438


>UniRef50_D2TK06 Anaerobic C4-dicarboxylate transporter n=1 Tax=Citrobacter
           rodentium ICC168 RepID=D2TK06_CITRO
          Length = 429

 Score =  379 bits (973), Expect = e-103,   Method: Composition-based stats.
 Identities = 200/435 (45%), Positives = 289/435 (66%), Gaps = 10/435 (2%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAAIGVKPGNIPFDVISIIMAVIAAI 60
           M++V+ ++VLL +++G R+GGIG+GFAGG GV+VL+A+G  PG++P  VI  IM VI AI
Sbjct: 1   MILVQFLVVLLFLYIGMRVGGIGVGFAGGAGVIVLSALGATPGDMPMLVIVFIMVVIVAI 60

Query: 61  SAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAK 120
           +AMQ AGG++YLV  TE+LLRR P+ + I AP+ T+ LT+ A TG +S A +PVI  VAK
Sbjct: 61  AAMQEAGGIEYLVDLTERLLRRYPRLLVITAPLSTWLLTMMASTGQVSFACMPVIVGVAK 120

Query: 121 EQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEG--HGISYLHLLSVVIPSTLLA 178
           E  +KP R L+ +V ++ + I ASPISAAV++ S ++E    G  Y+ L++V IPST LA
Sbjct: 121 ENNIKPTRALALSVSASLLGIVASPISAAVIFFSGILEKGHSGWGYIELIAVSIPSTFLA 180

Query: 179 VLVMSFLVTMLFNSKLSDDPIYRK-RLEEGLVELRGEKQIEIKSGAKTSVWLFLLGVVGV 237
           +LV S          L  D I ++ RL +  V+++   +  I   A  SV +F++G+V V
Sbjct: 181 LLVTSVSY-------LCWDRIRQQDRLYDNPVQVKARNERTIPPYAGRSVLIFIIGLVVV 233

Query: 238 VIYAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSAC 297
           ++YAI+ SP +GL+  P+M++  A + +ML VA L  V C+V+   + + S FK GM++C
Sbjct: 234 LVYAIVTSPKLGLIAHPVMSSGQARVEMMLGVALLIVVCCRVNVHKVPSGSVFKTGMTSC 293

Query: 298 ICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPM 357
           ICILGVAWLG TF+ +N  W++      +   P +LA+I   AS  LYSQAA+ K L P 
Sbjct: 294 ICILGVAWLGSTFMDSNQQWLQSAVSSHLLDSPIMLAIIIMAASCFLYSQAASTKILFPA 353

Query: 358 ALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLG 417
           AL++ ++P   VA F A S LFILP YPTL+AAV+MDDTG TR+G+ + +HPF +PG   
Sbjct: 354 ALSMGIAPAILVACFPATSSLFILPNYPTLLAAVEMDDTGYTRLGRHIIDHPFLLPGLAS 413

Query: 418 VALAVCFGFVLGSFM 432
           V L++ F   L   +
Sbjct: 414 VLLSMLFATGLAYLI 428


>UniRef50_UPI00019F11D6 anaerobic c4-dicarboxylate antiporter, Dcu family protein n=1
           Tax=Citrobacter youngae ATCC 29220 RepID=UPI00019F11D6
          Length = 428

 Score =  378 bits (970), Expect = e-103,   Method: Composition-based stats.
 Identities = 197/435 (45%), Positives = 282/435 (64%), Gaps = 10/435 (2%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAAIGVKPGNIPFDVISIIMAVIAAI 60
           M++V+  IVL+ +++G R+GGIG+GFAGG GVLVL  +G KPGN+P  VI  IM VI AI
Sbjct: 1   MVMVQFFIVLIFLYIGMRVGGIGVGFAGGAGVLVLGILGAKPGNMPMLVIVFIMVVIIAI 60

Query: 61  SAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAK 120
           SAMQ AGG+DYLV  TE+LLRR P+ + + API T+ LT+ A TG +S A +PVI  VAK
Sbjct: 61  SAMQEAGGIDYLVRLTERLLRRYPRLLVVTAPISTWLLTMMASTGQVSFACMPVIVGVAK 120

Query: 121 EQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVME--GHGISYLHLLSVVIPSTLLA 178
           E  +KP R L+ +V ++ + I ASPISAAV++ S ++E   HG  Y+ L+SV IP+T  A
Sbjct: 121 ENNIKPTRALALSVSASLLGIVASPISAAVIFFSGILEKNNHGWGYIELISVSIPATFFA 180

Query: 179 VLVMSFLVTMLFNSKLSDDPIYRK-RLEEGLVELRGEKQIEIKSGAKTSVWLFLLGVVGV 237
           +L  SF         L  D   ++ +L             E+  GA+ +V +F++G+V V
Sbjct: 181 LLFASFFY-------LCWDRFKQQDQLNNQPYIKEESIHQEVLPGARRAVLIFIIGLVVV 233

Query: 238 VIYAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSAC 297
           ++YAI+ SP +G++  P+MN+    + +M+ VA L    C+V+   I ++S FK GM++C
Sbjct: 234 LVYAIVASPKLGIISHPVMNSGQVRIGVMMGVALLIVACCRVNVHKISSTSVFKTGMTSC 293

Query: 298 ICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPM 357
           ICILGVAWLG TF+ NN  W++      +   PWLLA++    S  LYSQAA+ + L P 
Sbjct: 294 ICILGVAWLGSTFMDNNQQWLQAMVSGYLLHSPWLLALVIMLVSCFLYSQAASTQILFPA 353

Query: 358 ALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLG 417
           AL++ V+P   VA F A + LFILP YPTL+AAV++DDTG+T +G  + +HPF +PG + 
Sbjct: 354 ALSMGVAPGILVACFPATASLFILPNYPTLLAAVELDDTGSTHLGNKIIDHPFLLPGLIT 413

Query: 418 VALAVCFGFVLGSFM 432
             L++ F F L   +
Sbjct: 414 TLLSIAFAFALSLLI 428


>UniRef50_A7GZH5 Anaerobic C4-dicarboxylate transporter DcuA n=4 Tax=Proteobacteria
           RepID=A7GZH5_CAMC5
          Length = 423

 Score =  364 bits (936), Expect = 3e-99,   Method: Composition-based stats.
 Identities = 200/434 (46%), Positives = 279/434 (64%), Gaps = 14/434 (3%)

Query: 3   VVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAAI-GVKPGNIPFDVISIIMAVIAAIS 61
           ++E+I++   I L ARLGGIG+G AGGLG+++L  I GVKPG IP  V+ IIMAVI AIS
Sbjct: 1   MIEMIVLFGCIVLAARLGGIGVGLAGGLGLVILVFIMGVKPGEIPIAVMLIIMAVILAIS 60

Query: 62  AMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAKE 121
            MQ AGG+ Y+V  TE++LR +PKYI  LAP  T+ LT+  GTG  ++  L VI +VAKE
Sbjct: 61  VMQRAGGMAYMVKITERILRNHPKYINFLAPASTFILTVLTGTGYSAMTVLNVIQQVAKE 120

Query: 122 QGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAVLV 181
            GV+P +PLS+AVV++Q+AITASPISAA   +   +E  G+S+   L V++PS  +A LV
Sbjct: 121 NGVRPSQPLSSAVVASQLAITASPISAATAALYLTLEPMGVSFGSALMVIVPSAAIAALV 180

Query: 182 MSFLVTMLFNSKLSDDPIYRKRLEEGLVEL--RGEKQIEIKSGAKTSVWLFLLGVVGVVI 239
            +F+ +     +L DDPI+++R+++GLV      EK       AK SVWLFL  VV +VI
Sbjct: 181 AAFVASKQ-GVELKDDPIFQERVKKGLVSFESPEEKTARTTKEAKISVWLFLASVVFIVI 239

Query: 240 YAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSACIC 299
             +             +++ + I+I ML VA +    CKV  ++I  SS F +G  + I 
Sbjct: 240 MLLFKKQI-----GHDLSSRDIIVITMLFVAFVMVFPCKVPLEDIKKSSIFVSGAESFIV 294

Query: 300 ILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPMAL 359
           +LG+ WL  T +  +I  +K+ AGE+++ +P LLAVIFF  SA+L+SQ ATA  LMP+A 
Sbjct: 295 VLGITWLSSTAIGVHIPAVKEMAGELLKEYPALLAVIFFGTSAVLFSQGATAALLMPIAA 354

Query: 360 ALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLGVA 419
           +L V   T +ASF AVS L+I   YPT   A+  DDTG+     F+ NHPFF+PG L + 
Sbjct: 355 SLGVDAGTILASFVAVSALYITNIYPTTAFAISTDDTGS-----FIINHPFFLPGLLSIV 409

Query: 420 LAVCFGFVLGSFML 433
           ++V FGF L   +L
Sbjct: 410 VSVPFGFFLAKIVL 423


>UniRef50_A4N2Y1 Anaerobic C4-dicarboxylate transporter n=1 Tax=Haemophilus
           influenzae R3021 RepID=A4N2Y1_HAEIN
          Length = 389

 Score =  363 bits (932), Expect = 9e-99,   Method: Composition-based stats.
 Identities = 149/362 (41%), Positives = 216/362 (59%), Gaps = 8/362 (2%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVL-AAIGVKPGNIPFDVISIIMAVIAA 59
           M +++  IVLL IF+GAR+GGIG+G  GGLG+ +L    G+KP  +P DV+ +IMAV+AA
Sbjct: 4   MFLLQFAIVLLCIFVGARVGGIGLGVFGGLGLAILSFGFGLKPAGLPIDVMFMIMAVVAA 63

Query: 60  ISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVA 119
            +AMQ AGGLDY++    K+LRRNPK+IT +AP VT+  T+ AGTG+++ + LPVIAEV+
Sbjct: 64  AAAMQAAGGLDYMIKIATKILRRNPKHITFIAPAVTWLFTLLAGTGHVAYSVLPVIAEVS 123

Query: 120 KEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAV 179
           ++ G++P RP+S AV+++Q AI ASPI+AAVV + + +E  GI    +L V IPST+L +
Sbjct: 124 RQNGIRPERPMSMAVIASQFAIVASPIAAAVVAVVAYLEPQGIHLGDVLMVTIPSTILGL 183

Query: 180 LVMSFLVTMLFNSKLSDDPIYRKRLEEGLV-----ELRGEKQIEIKSGAKTSVWLFLLGV 234
            +    V  +   +L DDP Y++RL +             K++E+   AK SV LFL G 
Sbjct: 184 FLACLFVNKM-GKELKDDPEYQRRLNDPKYADIFASTTSVKEVEVSKTAKISVSLFLFGA 242

Query: 235 VGVVIYAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGM 294
           + VV+     S          M   + I IIMLS+  L  + CK D   I   S F AGM
Sbjct: 243 LLVVLMGAAPSIRPVFDG-KPMGMAHTIEIIMLSIGALIILTCKPDGTAITKGSVFHAGM 301

Query: 295 SACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKAL 354
            A I I G+AWLGDT +  +I  +K+    +++  PW  A   F    +       +  +
Sbjct: 302 RAVIAIFGIAWLGDTLMQAHITEVKEMVKGLVETAPWAFAFALFVTFCISKQPRRNSSNI 361

Query: 355 MP 356
           +P
Sbjct: 362 VP 363


>UniRef50_C5EXL5 Anaerobic C4-dicarboxylate transporter n=2 Tax=Proteobacteria
           RepID=C5EXL5_9HELI
          Length = 435

 Score =  327 bits (838), Expect = 7e-88,   Method: Composition-based stats.
 Identities = 168/311 (54%), Positives = 231/311 (74%), Gaps = 6/311 (1%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVL-AAIGVKPGNIPFDVISIIMAVIAA 59
           ML++++I++L AIF+G RLGGIGIG+AGG+GV++L   +G+ PG IP+DVI IIM+VIAA
Sbjct: 5   MLILQIIVLLGAIFVGIRLGGIGIGYAGGIGVIILGLGLGMTPGAIPWDVILIIMSVIAA 64

Query: 60  ISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVA 119
           ISAMQ+AGGLDYLV   E++LR NPKYI  LAP VTYFLTI AGTG+ + + +PVI EVA
Sbjct: 65  ISAMQLAGGLDYLVQIAERILRSNPKYINYLAPTVTYFLTILAGTGHTAFSMIPVIVEVA 124

Query: 120 KEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAV 179
           KEQ +KP  PLS AVVS+QIAITASP+SAAVVYM+ V+E  G SY  LL + IP+T +  
Sbjct: 125 KEQNIKPSAPLSIAVVSSQIAITASPVSAAVVYMTGVLEPLGWSYPLLLGIWIPTTFVGC 184

Query: 180 LVMSFLVTMLFNSKLSDDPIYRKRLEEGLVELR-GEKQIEIKSGAKTSVWLFLLGVVGVV 238
           ++ +F++TM ++  LS DP+Y++RL +GLV+   G + +E+K GAK SV +F++GV+ VV
Sbjct: 185 MITAFIMTMFYDLDLSKDPVYQERLAQGLVKAPVGAQNMELKEGAKLSVAIFVIGVLCVV 244

Query: 239 IYAIINSP---SMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMS 295
           +YA   S       L+E  ++    AI+  ML +ATL  ++CK+  D I ++S FK+GM 
Sbjct: 245 LYATAISKIGGKPVLIENVIVGRDAAIMSFMLGIATLIVMLCKIKPDKIADTSVFKSGMV 304

Query: 296 ACICI-LGVAW 305
           AC+CI   +AW
Sbjct: 305 ACVCIGCSLAW 315


>UniRef50_Q8CMX9 Anaerobic dicarboxylate transport n=11 Tax=Staphylococcus
           RepID=Q8CMX9_STAES
          Length = 444

 Score =  327 bits (838), Expect = 7e-88,   Method: Composition-based stats.
 Identities = 121/419 (28%), Positives = 230/419 (54%), Gaps = 17/419 (4%)

Query: 20  GGIGIG-FAGGLGVLVLAAIGVKPGNIPFDVISIIMAVIAAISAMQVAGGLDYLVHQTEK 78
           G +G G FA    ++++    + PG+ P   + II+++  A   +Q  GG+DYLV+   +
Sbjct: 35  GALGCGIFAIVAQLIMIFGFQLPPGSAPVTAVLIILSIGIAGGTLQATGGIDYLVYIASR 94

Query: 79  LLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAKEQGVKPCRPLSTAVVSAQ 138
           ++ R PK I  +AP++ +      GT NI+L+  P+IA+ A++  ++P R L+ +V++A 
Sbjct: 95  VIERFPKSIIFIAPMIVFVFVFGIGTANIALSLEPIIAKTAQKARIQPKRALTASVLTAN 154

Query: 139 IAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAVLVMSFLVTMLFNSKLSDDP 198
           +A+  SP ++A  Y+ SV+ G+ IS    LS+V+P+ L+++L++S   T +   +   D 
Sbjct: 155 LALLCSPAASATAYIISVLAGYEISMGKYLSIVLPTALISMLMLSTFCTFVGRKEHVRD- 213

Query: 199 IYRKRLEEGLVELRGEKQIEIKSGAKTSVWLFLLGVVGVVIYAIINSPSMGLVEK---PL 255
              + ++   VE++ +  +++    K  V  FLL V+G++ + I  +             
Sbjct: 214 ESERLVQMPEVEIKNDFSLKV----KIGVISFLLCVMGILTFGIFPNLMPQFNVNGDVVK 269

Query: 256 MNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSACICILGVAWLGDTFVSN-- 313
           +  T  +   M   AT+  ++ K++T +IL+S+  ++ M A   +LG  WLG T  +   
Sbjct: 270 VEMTEIVQFFMYLSATINLLLIKINTSDILSSNITQSAMGALFAVLGPGWLGATIFNAPH 329

Query: 314 NIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPMALALNVSPLTAVASFA 373
           N+  +K+  G +I   PWL+ ++    + ++ SQ ATA  ++P+ ++L + P+  VA   
Sbjct: 330 NLKILKNDIGSIISEVPWLVIILVSVVAMIVISQTATASIMVPIVMSLGIPPIYFVAMVQ 389

Query: 374 AVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLGVALAVCFGFVLGSFM 432
            ++  F++P  PTL+ AV++D+TG TR         F IPG   + ++V  GFV+ + +
Sbjct: 390 TLNVNFVIPAQPTLLFAVELDETGRTR------PTSFMIPGFFVITVSVITGFVIKTIL 442


>UniRef50_A7ZC15 Anaerobic C4-dicarboxylate membrane transporter n=31
           Tax=Proteobacteria RepID=A7ZC15_CAMC1
          Length = 559

 Score =  282 bits (723), Expect = 1e-74,   Method: Composition-based stats.
 Identities = 85/278 (30%), Positives = 143/278 (51%), Gaps = 17/278 (6%)

Query: 2   LVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAA-IGVKPGNIPFDVISIIMAVIAAI 60
             ++LI+VL  +F GA+ GG+ +G  GG+G+++L     +KPG    DVI  I+AV+ A 
Sbjct: 13  FFLQLIVVLGCLFYGAKKGGMALGVLGGIGLVILVFAFDLKPGKPAIDVILTILAVVVAS 72

Query: 61  SAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAK 120
           + +Q AGGLD ++   E+ LR++P+ +  LAPI  + LT+  GTG+     LP+I +V+ 
Sbjct: 73  ATLQAAGGLDVMLQIAERALRKHPRTVCYLAPICGWTLTVLCGTGHTVYTLLPIIYDVSM 132

Query: 121 EQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHG-------ISYLHLLSVVIP 173
           + G++P RP++   +S+Q+AI ASP+S A V M +V+ G G        SY+ LL V IP
Sbjct: 133 KSGIRPERPMAATTISSQLAIIASPVSVAGVSMVAVLLGTGTVHIEGFTSYVDLLKVTIP 192

Query: 174 STLLAVLVMSFLVTMLFNSKLSDDPIYRKRLEEGLVELR--------GEKQIEIKSGAKT 225
           ST L VL +    ++     L  DP ++ ++ +                  +++      
Sbjct: 193 STFLGVLCIGT-YSVFRGKDLDKDPEFQAKIADPEQRKYIYGSDESHSLIGVKLPKKQWN 251

Query: 226 SVWLFLLGVVGVVIYAIINSPSMGLVEKPLMNTTNAIL 263
            +W+FL  +  V +                  +   I+
Sbjct: 252 IMWIFLATIAVVAVLGYYKQLRPSWTSNVPGKSIEIIV 289



 Score =  221 bits (564), Expect = 4e-56,   Method: Composition-based stats.
 Identities = 67/180 (37%), Positives = 104/180 (57%)

Query: 252 EKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSACICILGVAWLGDTFV 311
           +   +   + I I ML  A++  +   +    I  +  F +GM A + I G++W+ +T  
Sbjct: 375 KTAPLGMVDTIQIFMLLAASIMMIYSGIKAAKIGQNEIFHSGMVALVAIYGISWMAETMF 434

Query: 312 SNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPMALALNVSPLTAVAS 371
           +++ID +K + GEV++ +PW+  ++    S  L SQAA A   +P+A+ + V P   VA 
Sbjct: 435 NSHIDMLKGSLGEVMKAYPWMYIIVGMLISKFLNSQAAAAATFVPLAVQIGVHPGVIVAF 494

Query: 372 FAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLGVALAVCFGFVLGSF 431
             A  G FILPTYP+ +AAVQ D +GTT IGK+V NH F IPG +GV  +   G+VL + 
Sbjct: 495 ATACYGYFILPTYPSDLAAVQFDRSGTTHIGKYVINHSFIIPGFIGVFSSCAVGWVLANI 554


>UniRef50_C6MSZ8 Anaerobic c4-dicarboxylate antiporter, Dcu family n=2
           Tax=Proteobacteria RepID=C6MSZ8_9DELT
          Length = 546

 Score =  270 bits (690), Expect = 9e-71,   Method: Composition-based stats.
 Identities = 117/280 (41%), Positives = 168/280 (60%), Gaps = 18/280 (6%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAA-IGVKPGNIPFDVISIIMAVIAA 59
           M  +E ++VL AIF+GARLGGIG+G  GGLG+ +L     ++P   P DV+ +I AV+ A
Sbjct: 1   MFWLEFLVVLAAIFIGARLGGIGLGVMGGLGLALLTFLFHLQPTAPPIDVMLMIAAVVTA 60

Query: 60  ISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVA 119
              +Q AGGLDYLV   EK+LR NP  IT L P+VTYF T+FAGTG+++ + LPVIAEVA
Sbjct: 61  AGVLQAAGGLDYLVSLAEKILRNNPDRITFLGPMVTYFFTLFAGTGHVAYSVLPVIAEVA 120

Query: 120 KEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVM------EGHGISYLHLLSVVIP 173
           +E GV+P RP+S AV+++Q AITASPI+AA V +  ++       G  +  + +L V IP
Sbjct: 121 RETGVRPERPMSIAVIASQQAITASPIAAATVALLGLLGGSAAKFGFNVELIDILKVCIP 180

Query: 174 STLLAVLVMSFLVTMLFNSKLSDDPIYRKRLEEGLVELRGEKQIE----------IKSGA 223
           STL+ VL+ +F+   L    L  DP Y++RL+EGLV        +            + A
Sbjct: 181 STLMGVLIAAFISNKL-GKDLDKDPEYQQRLKEGLVPPPRSSSSDTAKVNEAIRNTPASA 239

Query: 224 KTSVWLFLLGVVGVVIYAIINSPSMGLVEKPLMNTTNAIL 263
           K +V LFL+G + VV++                  ++ ++
Sbjct: 240 KVAVALFLVGTILVVLFGSFPQLRPEWSVGNDTRISHIVV 279



 Score =  222 bits (565), Expect = 3e-56,   Method: Composition-based stats.
 Identities = 75/191 (39%), Positives = 111/191 (58%), Gaps = 1/191 (0%)

Query: 243 INSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSACICILG 302
            +       ++  M   + I I+ML++A L  ++CKV    +   S F AG+ A I I G
Sbjct: 357 FDEKRPAQNKEK-MGMPHVIEIVMLAIAALMLLLCKVKVSRVAEGSVFIAGVQAVIAIFG 415

Query: 303 VAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPMALALN 362
           +AW+GDTF   N++++  +   ++   PWL A   F  S LLYSQAAT +ALMP+ ++L 
Sbjct: 416 IAWMGDTFFQGNMEFLSGSIKGMVTTAPWLFAFALFILSILLYSQAATVRALMPLGISLG 475

Query: 363 VSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLGVALAV 422
           +     +A F AV+G F +P YPT+VAA+  D TGTT IG++V NH F IPG +    ++
Sbjct: 476 IPAPFLIAMFPAVNGYFFIPNYPTVVAAINFDRTGTTGIGRWVLNHSFMIPGLVATFSSI 535

Query: 423 CFGFVLGSFML 433
             GF+L   M 
Sbjct: 536 GIGFLLVKLMF 546


>UniRef50_Q2EX27 DcuA (Fragment) n=20 Tax=Bacteria RepID=Q2EX27_ECOLX
          Length = 180

 Score =  215 bits (548), Expect = 3e-54,   Method: Composition-based stats.
 Identities = 180/180 (100%), Positives = 180/180 (100%)

Query: 241 AIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSACICI 300
           AIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSACICI
Sbjct: 1   AIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSACICI 60

Query: 301 LGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPMALA 360
           LGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPMALA
Sbjct: 61  LGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPMALA 120

Query: 361 LNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLGVAL 420
           LNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLGVAL
Sbjct: 121 LNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLGVAL 180


>UniRef50_UPI0001854D97 anaerobic C4-dicarboxylate transporter n=1 Tax=Helicobacter pylori
           HPKX_438_CA4C1 RepID=UPI0001854D97
          Length = 170

 Score =  169 bits (429), Expect = 2e-40,   Method: Composition-based stats.
 Identities = 72/171 (42%), Positives = 107/171 (62%), Gaps = 2/171 (1%)

Query: 122 QGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAVLV 181
           + +KP  PLS AVVS+Q+AITASP+SAAVV+MS ++E  G +YL LL V IP+T LA ++
Sbjct: 1   KTIKPKAPLSLAVVSSQVAITASPVSAAVVFMSGILEPLGANYLTLLMVWIPTTFLACMI 60

Query: 182 MSFLVTMLFNSKLSDDPIYRKRLEEGLVELRG-EKQIEIKSGAKTSVWLFLLGVVGVVIY 240
            +F++    + +L  DP Y +RL          +++ E    AK S+W+F+ GVV +V Y
Sbjct: 61  TAFMMGFT-DLRLDSDPNYLERLNTRNFSPPTIKEEKETSKSAKLSLWIFIGGVVAIVFY 119

Query: 241 AIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFK 291
           A   S ++  V   ++    AI+  MLSVATL  + CK++ + I +SS FK
Sbjct: 120 ASAISKNIAFVSPVVLGRDYAIVSFMLSVATLIVLFCKINANEIAHSSVFK 170


>UniRef50_P40684 Anaerobic C4-dicarboxylate transporter dcuA (Fragment) n=7
           Tax=Proteobacteria RepID=DCUA_SERMA
          Length = 132

 Score =  136 bits (344), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 121/132 (91%), Positives = 127/132 (96%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAAIGVKPGNIPFDVISIIMAVIAAI 60
           ML VEL+IVLLAIFLGARLGGIGIGFAGGLGVL LA IGVKPGNIPFDVISIIMAVIAAI
Sbjct: 1   MLAVELVIVLLAIFLGARLGGIGIGFAGGLGVLALALIGVKPGNIPFDVISIIMAVIAAI 60

Query: 61  SAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAK 120
           SAMQVAGG+DYLV QTEKLLR+NPK+ITILAPIVTYFLTIFAGTGNISL+ LPVIAEVAK
Sbjct: 61  SAMQVAGGMDYLVQQTEKLLRKNPKHITILAPIVTYFLTIFAGTGNISLSALPVIAEVAK 120

Query: 121 EQGVKPCRPLST 132
           EQG+KPCRPLST
Sbjct: 121 EQGIKPCRPLST 132


>UniRef50_UPI00019127C3 anaerobic C4-dicarboxylate transporter n=1 Tax=Salmonella enterica
           subsp. enterica serovar Typhi str. AG3
           RepID=UPI00019127C3
          Length = 99

 Score =  104 bits (261), Expect = 5e-21,   Method: Composition-based stats.
 Identities = 87/99 (87%), Positives = 95/99 (95%)

Query: 182 MSFLVTMLFNSKLSDDPIYRKRLEEGLVELRGEKQIEIKSGAKTSVWLFLLGVVGVVIYA 241
           MSFLVTMLFNSKLSDDPIYRKRLEEGL+ELRGEKQIEIK  AK SVWLFLLGV+ VV+YA
Sbjct: 1   MSFLVTMLFNSKLSDDPIYRKRLEEGLIELRGEKQIEIKPMAKNSVWLFLLGVICVVVYA 60

Query: 242 IINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVD 280
           I+NSPS+GLVEKPLMNTTNAILIIMLSVATLTT++CKV+
Sbjct: 61  IVNSPSLGLVEKPLMNTTNAILIIMLSVATLTTILCKVE 99


>UniRef50_Q1CLI8 Anaerobic C4-dicarboxylate transporter n=8 Tax=Yersinia pestis
           RepID=Q1CLI8_YERPN
          Length = 103

 Score = 93.4 bits (231), Expect = 1e-17,   Method: Composition-based stats.
 Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 3/93 (3%)

Query: 239 IYAIINSPSMGLVEKPLM---NTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMS 295
           +             K  +   +    I ++ML    +  + CKV   +I N + FKAGM 
Sbjct: 1   MLGAFADLRPAFEVKGKLQSLSMNLVIQMMMLIAGAVILIGCKVKPSDISNGAVFKAGMV 60

Query: 296 ACICILGVAWLGDTFVSNNIDWIKDTAGEVIQG 328
           A   + GVAW+ DTF   ++  ++    +V++ 
Sbjct: 61  AIFSVFGVAWMSDTFFQAHMGELRLVLEDVVKA 93


>UniRef50_C3HV44 Anaerobic C4-dicarboxylate transporter dcuB n=1 Tax=Bacillus
           thuringiensis IBL 200 RepID=C3HV44_BACTU
          Length = 134

 Score = 84.9 bits (209), Expect = 6e-15,   Method: Composition-based stats.
 Identities = 52/117 (44%), Positives = 76/117 (64%), Gaps = 6/117 (5%)

Query: 1   MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAA-IGVKPGNIPFDVISIIMAVIAA 59
           M  ++ + +LL IF+GARLGG+G+G  GG+G+ +L     ++P   P DV+ +I+AVI A
Sbjct: 1   MFWLQFLTLLLCIFIGARLGGVGLGVMGGVGMAILVFVFHLQPTAPPIDVMLMILAVITA 60

Query: 60  ISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIA 116
             A+Q AGG+DYLVH  EK LR+NPK IT L  +    L I++    + L TLP++ 
Sbjct: 61  AGALQAAGGMDYLVHLAEKALRKNPKRITFLLQL----LLIYSHYVQV-LVTLPILY 112


>UniRef50_UPI00019127C2 anaerobic C4-dicarboxylate transporter n=1 Tax=Salmonella enterica
           subsp. enterica serovar Typhi str. AG3
           RepID=UPI00019127C2
          Length = 60

 Score = 43.3 bits (101), Expect = 0.017,   Method: Composition-based stats.
 Identities = 30/32 (93%), Positives = 32/32 (100%)

Query: 150 VVYMSSVMEGHGISYLHLLSVVIPSTLLAVLV 181
           +VYMSSVMEGHGISY+HLLSVVIPSTLLAVLV
Sbjct: 1   MVYMSSVMEGHGISYIHLLSVVIPSTLLAVLV 32


>UniRef50_Q03HQ5 C4-dicarboxylate transporter n=5 Tax=Bacteria RepID=Q03HQ5_PEDPA
          Length = 467

 Score = 42.9 bits (100), Expect = 0.021,   Method: Composition-based stats.
 Identities = 77/397 (19%), Positives = 152/397 (38%), Gaps = 28/397 (7%)

Query: 51  SIIMAVIAAISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFA----GTGN 106
            +I+ +    + M   G     VH   K + +  K I +LAPIV     + +       N
Sbjct: 79  FVILILGGYSAYMNHIGANQVTVHALTKPITKI-KSIYLLAPIVFLIGNLLSLVIPSASN 137

Query: 107 ISLATLPVIAEVAKEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSV--MEGHGISY 164
           +++  L  +  V +  G+   R  S A++     I  +P+ A  V ++S   M      +
Sbjct: 138 LAIILLATLYPVLRSAGM--SRLTSAAIIGTSATIVPTPLGADNVAIASQFHMSVTDYVF 195

Query: 165 LHLLSVVIPSTLLAVLVMSFLVTMLFNSKLSDDPIYRKRLEEGLVELRGEKQIEIKSGAK 224
                + IP TLLA+ ++ +L     + K  ++  Y   L +   +           G K
Sbjct: 196 QKHALISIP-TLLAITIVHYLWQKYQDKKHPEELSYSSELSQNKEQDSTASPKVSYKGFK 254

Query: 225 TSVWLFLLGVVGVVIYAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNI 284
              +++ L  +  ++  +I   +   +   L  +   + ++   +A L  +  K     +
Sbjct: 255 --AFIYGLLPLLPIVILLIIFFTNIFLHTKLNISVQLVSLLSFVIAVLVEIFNKKHPQIV 312

Query: 285 LN-SSTFKAGMSACICILGVAWLGDTFVSNN-----IDWIKDTAGEVIQGHPWLLAVIFF 338
           L  +S F  GM + + I+ +      FV        ID I+ T   +      L  V+  
Sbjct: 313 LKETSNFFEGMGSVMSIVALLVSAQVFVQGLTSIGIIDLIQKTMQTMNSSGIVLPVVMVV 372

Query: 339 FASALLYSQA-------ATAKALMPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAV 391
           F + ++           A    L+P++ A  +SP+        ++G  +    P  VAAV
Sbjct: 373 FTAIIVLLSGSGTALLYAMIPLLLPLSKAAGISPIALSVPMQ-LAGNLLRAISP--VAAV 429

Query: 392 QMDDTGTTRIGKFVFNHPFFIPGTLGVALAVCFGFVL 428
            +   GTT++          +P   GV + +    ++
Sbjct: 430 ILIVAGTTKLSPVKIVKRTSVPMVFGVIMMLVMSLLI 466


>UniRef50_P25360 Inorganic phosphate transporter PHO87 n=19 Tax=Saccharomycetaceae
           RepID=PHO87_YEAST
          Length = 923

 Score = 42.1 bits (98), Expect = 0.040,   Method: Composition-based stats.
 Identities = 53/277 (19%), Positives = 102/277 (36%), Gaps = 46/277 (16%)

Query: 71  YLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAKEQGVKPCRPL 130
           +L+          P+ + ++A  V +FL+++    N++   L           +    P 
Sbjct: 572 WLLALAGT----KPRNVLLMAMSVVFFLSMWI--SNVASPVLTYSLLTPLLDPLDYTSPF 625

Query: 131 STAVV-----SAQIAITASPISAA--VVYMSSVMEGHGISYLHLLSVVIPSTLLAVLV-- 181
           + A+V     SA I   ASPIS+   ++ M   ++ +GI +    +V +P+ +L++L   
Sbjct: 626 AKALVMGVALSADIGGMASPISSPQNIISM-QYLKPYGIGWGQFFAVALPTGILSMLCSW 684

Query: 182 MSFLVTMLFNS-KLSD-DPIYRKRLEEG------------LVELRGEKQIEIKSGAKTS- 226
              ++T      KL    PI  +   +             L  +  + +    S  + + 
Sbjct: 685 ALMILTFKIGKTKLEKFKPIRTRFTIKQYFIIIVTIATILLWCVESQIESAFGSSGEIAV 744

Query: 227 ---VWLFLLGVVGVVIYAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDN 283
              V  F  G++    +              ++      L   +S + L   I +     
Sbjct: 745 IPIVLFFGTGLLSTKDFNTFP------WSIVVLAMGGIALGKAVSSSGLLVTIARALQKK 798

Query: 284 ILNSSTFKAGMSACICILGVAWL-GDTFVSNNIDWIK 319
           I N   F     A +CI G+  L   TFVS+ +  I 
Sbjct: 799 IQNDGVF-----AILCIFGILMLVVGTFVSHTVSAII 830


>UniRef50_C3KGP7 MIP04527p (Fragment) n=9 Tax=Sophophora RepID=C3KGP7_DROME
          Length = 708

 Score = 41.7 bits (97), Expect = 0.054,   Method: Composition-based stats.
 Identities = 34/202 (16%), Positives = 81/202 (40%), Gaps = 9/202 (4%)

Query: 31  GVLVLAAIGVKPGN------IPFDVISIIMAVIAAISAMQVAGGLDYLVHQTEKLLRRNP 84
           G+ +L A+G +P        I F+ + +++ ++  ++ M   G  D++     ++ + NP
Sbjct: 251 GIAILTALGNRPTLETIISWIDFETLILLLGMMILVAIMSETGVFDWMAVLAYRISKGNP 310

Query: 85  KYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAKEQGVKPCRPLSTAVVSAQIAITAS 144
             + +L   +T  ++       + L   P+   + +   V+    L   V+ + I  T +
Sbjct: 311 WPMLLLLSSITAIMSCMLDNVTMLLLMAPIAIRLCEAMAVQTPLVLIVVVMYSNIGGTLT 370

Query: 145 PIS---AAVVYMSSVMEGHGISYLHLLSVVIPSTLLAVLVMSFLVTMLFNSKLSDDPIYR 201
           P+      ++  +S +   G+ +L     ++P  LLA +    ++ +     L      +
Sbjct: 371 PVGDPPNVIIATNSEVISAGVDFLDFTIHMLPGVLLAAVAGYAVMYVTMRKSLFKLEEQQ 430

Query: 202 KRLEEGLVELRGEKQIEIKSGA 223
             L       R     +I + A
Sbjct: 431 LELAAERENSRRRSSADITARA 452


  Database: uniref50.fasta
    Posted date:  Mar 8, 2010 10:38 AM
  Number of letters in database: 1,040,396,356
  Number of sequences in database:  3,077,464
  
Lambda     K      H
   0.319    0.157    0.446 

Lambda     K      H
   0.267   0.0479    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,062,742,449
Number of Sequences: 3077464
Number of extensions: 104070500
Number of successful extensions: 601074
Number of sequences better than 1.0e-01: 609
Number of HSP's better than  0.1 without gapping: 76
Number of HSP's successfully gapped in prelim test: 1118
Number of HSP's that attempted gapping in prelim test: 599305
Number of HSP's gapped (non-prelim): 2243
length of query: 433
length of database: 1,040,396,356
effective HSP length: 132
effective length of query: 301
effective length of database: 634,171,108
effective search space: 190885503508
effective search space used: 190885503508
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.1 bits)
S2: 95 (41.0 bits)
