Reference sequence (query): batch____ Identities normalised by aligned length. Colored by: property
HSP processing: ranked Search cycle: 3
1 [ . . . . : . . . . 1 . . . . : . . . . 2 . . ] 222
batch____ bits E-value N 100.0% 1:222 IGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELI
1 UniRef50_Q2JUI3 Isopropylmalate/isohomocitr... 243 3e-63 1 42.5% 1:221 13:218 IGPEVTRAMTTVLEA-------SGVDLEWIRVEAGVEVIEKYGTP--LPPQVLESIRETRVAIKGPIGTPVGTGFRSVNVAIRKELDLYANLRPAKSLPGIKSPFQ---DIDLVVVRENTEDLYAGIEFERGTPEAAHAREEMMRLSGKF---IREGSAIGIKPISEFGSRRIVKFAFEYARQNGRKKVTAVHKANIMKFTDGLFLQVAREVAQEYPDIEF-
2 UniRef50_B7UV18 Isocitrate dehydrogenase [N... 239 7e-62 1 78.8% 1:222 39:260 IGVDISPVMIKVVDAAVEKAYKGERKIAWMEVYAGEKATQVYDQDTWLPQETLDAVRDYVVSIKGPLTTPVGGGIRSLNVALRQQLDLYVCQRPVRWFEGVPSPVKKPGDVDMVIFRENSEDIYAGVEWKAGSPEAEKVIKFLTEEMGVKKIRFTENCGIGIKPVSQEGTKRLVRKALQYAVDNDRSSVTLVHKGNIMKFTEGAFKDWGYEVARDEFGAELL
3 UniRef50_Q6GG12 Isocitrate dehydrogenase [N... 235 1e-60 1 66.2% 1:222 29:248 IGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAFDTTGE--WLPQETLDTIKEYLIAVKGPLTTPIGGGIRSLNVALRQELDLFTCLRPVRWFKGVPSPVKRPQDVDMVIFRENTEDIYAGIEFKEGTTEVKKVIDFLQNEMGATNIRFPETSGIGIKPVSKEGTERLVRAAIQYAIDNNRKSVTLVHKGNIMKFTEGSFKQWGYDLALTEFGDQVF
4 UniRef50_D2RVT1 Isocitrate dehydrogenase, N... 233 3e-60 1 58.6% 1:222 41:260 IGKDVGPAAQKVLEAAAE---ATGRDISWMRVYAGESAREEYGEDVNLPDETVDAIREHRVAIKGPLTTPVGAGFRSLNVALRQTLDLYANVRPTYYLDGVPSPMKAPEEMDMVTFRENTEDVYAGIEWEAGTDEVEQVREFVEDEMGFDETMHDGPIGIGLKPITEKGSKRLVREAIDYALEHDRDKVTLVHKGNIMKFTEGQFGDWGMEVaeEYPDDEVF
5 UniRef50_A9B3D4 Isocitrate/isopropylmalate ... 231 1e-59 1 40.0% 2:221 14:219 -GPELAEATRRVLEA-------TGVAFDWDIQDAGVDVMEQLGTP--LPDSVLESIRSTKVALKAPITTPVGTGFRSVNVAIRKELDLYACVRPCRSYPGVRSRF---ENIDLVVVRENTEDLYAGIEFERGTDEVAELRNWLLQKRPNALIKEPG--GISIKPMSVPGSERIVRFAFEYARANKRKKVTAVHKANIMKFSDGLFLEVAREVAKEYPDIEF-
6 UniRef50_P41560 Isocitrate dehydrogenase [N... 230 3e-59 1 70.7% 1:222 37:258 IGVDVTPPMLKVVNAAVAKAYGGDRKIEWLEVYAGEKATKMYDSETWLPEETLNILQEYKVSIKGPLTTPVGGGMSSLNVAIRQMLDLYVCQRPVQWFTGVPSPVKRPSEVDMVIFRENTEDIYAGIEYKAGSDKAKSVIKFLIEEMGASNIRFTENCGIGIKPVSKEGSQRLVRQAIQYAIDNNKDSVTLVHKGNIMKFTEGAFKDWGYELAIEEFGASLL
7 UniRef50_C0WN79 Isocitrate dehydrogenase [N... 224 1e-57 1 53.4% 1:221 29:247 IGPEIWKAAKTVFDAAVKKAYDGQKQVNWLPLLAGETAYKKTGQ--WLPDKTLATLREYLVGIKGPLTTPIGIGHRSINVTLRQKLDLYACFRPVTYYPGTPSPVVHPENVNIDVFRENTEDIYAGIESDVDTKDAEEWKSLLAKQDKLSKVRFPDTSAFAIKPISKQGSTRLVDAAIDYAFANNRHTLTLVHKGNIMKKTEGGFKKWGYEAAEKYGDKVF-
8 UniRef50_C1F3J9 Isocitrate dehydrogenase n=... 223 3e-57 1 31.8% 1:220 32:218 IGPEITAAVMSILSAA-------GAHLDAEYVEVGEQVYLR-GNTSGIPQEAWDSIARTRVMLKGPITTPQGGGYKSLNVTMRKTLGLYANVRPCRTYKPIVT--TRHPDMDVVIVRENEEDLYAGIEHR-----------------------QTQDVAQCLKLITRSGSERIARYAFEYARQHGRSKITCMIKDNIMKLTDGLFHRVFDEVAREYPEIQ--
9 UniRef50_UPI0001C163C2 Isocitrate dehydrogenase NA... 218 1e-55 1 56.1% 2:222 38:265 -GIDIWPATEKVLDAAVAKAYNGKRKISWFKVYAGDEACDLYGTYQYLPQDTLTAIKEYGIAIKGPLTTPIGGGIRSLNVALRQIFDLYACVRPCRYYAGTPSPHKSPDKLDVIVYRENTEDIYLGIEWKQGSEIGERLINILNKDLIPakKQIPLDAGIGIKPISRSGSQRLVRRALKHALQLPKEkvTLVHKGNIMKYTEGAFRDWGYELATQEFRAECV
10 UniRef50_C7P3E9 Isocitrate dehydrogenase, N... 216 3e-55 1 54.5% 1:222 43:260 IGKDVGPAAQKVLEAAAN---ATGREISWMRVFAGESAREKYDEN--LPDDTVNAIDEHRVAIKGPLTTPVGAGFRSLNVALRQTLDFYSNVRPTYYLDGVPSPMKAPEEMDMVTFRENTEDVYAGIEWEAGTEEVEQVREFVEEDMGFDDVMHDGPIGIGIKPITEFGSKRLVRKAIDYAIEHDRDKVTLVGKGNIMKFTEGQFTEWGMEVaeEYPDDEVF
11 UniRef50_Q9ZN36 Isocitrate dehydrogenase [N... 214 1e-54 1 66.2% 1:222 40:267 IGSDITPAMIKVVDSAVQKAYKGEKKIAWYEVFVGEKCYQKFKdeQWLLPDTIEAINHYKVSIKGPLTTPIGEGFRSLNVALRQKMDLYVCLRPVRWY-GSPSPVKEPQKVDMVIFRENSEDIYAGIEWQEGSAEAKKLIHFLQNELKVEKIRFPESSGVGIKPISKEGTERLVRKAIEYAIDNDKPSVTFVHKGNIMKYTEGAFMKWGYALAQKEFNAQVI
12 UniRef50_A4WLX6 Isocitrate dehydrogenase (N... 214 2e-54 1 51.8% 1:222 55:271 IGPEVAYAAIKVANEAVEKAYGKSRQITWYEIVVGEKAEKLFGN--RLPDQSIEVLRKIRVFLKAPLETPVGGGFRSINVTLRQLFDLYANIRPVKYFPGLPSPLRRPELVDLVIFRENTEDVYAGIEWPYNSPEAAKIREFLRREFGV---NIRDDAGIGIKPISKFGTQRIARLALKFAIENKRRVVTVMHKGNIQKYTEGAFKEWAFEVARNEFREHVV
13 UniRef50_P96318 Isocitrate dehydrogenase [N... 213 4e-54 1 51.8% 1:222 43:258 IGPEIVESAKKVLDAAVDKAYGGTRRIVWWEVTAGEEAQKECG--SLLPDGTLQAFKLARVNLKGPLTTPVGGGFRSLNVTLRMVLDLYSNVRPVKWY-GQPTPHCHPENIDWVIFRENTEDVYAGIEWPFDSPEAQKIRDFLKKEFGI---ELTPDTGIGIKPISKWRTQRHVRRAMEWAIRNGYKHVTIMHKGNIMKYTEGAFRQWAYDLILSEFRDYVV
14 UniRef50_Q1IJA8 Isocitrate dehydrogenase (N... 212 5e-54 1 28.3% 1:219 13:196 IGPEVTSAAVRVLEA-------TGLKFEWESFAAGAEAYEKY--KEYIPKELNESIERTRIGLKGPVTTPIGGGFSSINVELRKRFELYANVRPIRNLPGVHTRYP---GVDLVVVRENTEGLYSGIEHEVVPGVVE-----------------------SLKIITEKASTRISKFAFNYARKMGRKKIHSIHKANIMKMSDGLFIRCSRNISKEYPEI---
15 UniRef50_C4Q3D3 Unc-13 (Munc13), putative n... 212 5e-54 1 30.8% 1:221 1987:2172 IGPEISAAVQEIFKFA-------DVPIKWESVDVTPRPTE--DGRFRMPQSSLDIIRKHGIGLKGPLATPIGKGHQSLNLALRKEFNLYANVRPCKSIEGYETPYK---NVDLVTVRENTEGEYSGIEHVIVDGVVQ-----------------------SIKLITEEASRRVARFAFQYAKDNGRRSVTAVHKANIMRMSDGLFLRVCREEAAHHREIEF-
16 UniRef50_Q0D0R7 Isocitrate dehydrogenase su... 210 3e-53 1 27.1% 1:221 65:249 IGPEISQSVKDIFSAA-------NAPIKWEPVDV--TPILKDGK-TAIPDDAIESVRRNYVALKGPLATPVGKGHVSLNLTLRRTFNLFANVRPCRSIAGYKTPY---DNVDTVLIRENTEGEYSGIEHVVVDGVVQ-----------------------SIKLITKEASERVLRFAFQYARSINKKKVRVVHKATIMKMSDGLFLNTAREIAKDFPDVEF-
17 UniRef50_UPI000150AB37 dehydrogenase, isocitrate/i... 209 7e-53 1 26.8% 1:220 315:499 IGPEISQAVCDIFAAAK-------VPIDWEHHEIYTKPINEAGD--LIKEESLNAVINYKWGLKGPFATPIGKGYRSLNVTMRKKLNLFANVRPCRSLAGVKTPYS---NVDLVTIRENTEGEYSGLEHAVVPGVVE-----------------------NLKIISQPACENIARYAFEFARKNNRKKVVACHKAGVMKKGDGLFINTCKKISSEYPEIE--
18 UniRef50_P70787 Probable tartrate dehydroge... 208 9e-53 1 23.2% 1:220 14:215 IGPEVIAAGLQVLEALEKR--SGDFSIHTETFDWGSDYYKKNG--VMMPADGLEQLKKFDAIFFGAVGAPDVPDhwGLRLPICQGFDQYANVRPTKVLPGITPPLRnpGDLDWVIVRENSEGEYSGHGGRAHKG-------------------LPEEVGTEVAIFTRVGVTRIMRYAFKLAQARPRKLLTVVTKSNAQRHGMVMWDEIAAEVSKEFPDVT--
19 UniRef50_Q3IKZ8 Isocitrate dehydrogenase, s... 208 9e-53 1 54.6% 1:218 42:258 VGQDVMPVMRKVVDSAIAHCYQAKRKIHWMQVYNGEQAAKLY-DGDWFPQETINAVRECKIAIKGPLTTPLGGGFRSLNVALRQEMDLFVNMRTIKGFSALPSPLKNPYLTNITVLRDSSEDVYSGIEWQAGSVESEKVLDFLCEEMGVTRLRFTQECGIGIKNISKEGSERLVRYAINYALKNNSESLTLVHKGNVLKFTDGAFKRWGFALAKREYQ----
20 UniRef50_Q55BI2 Isocitrate dehydrogenase [N... 208 1e-52 1 24.5% 1:220 34:212 IGPEISESVKRVFSAVKA-------PIEWETVVV--------DANTGISKEVIESISKNKIGLKGPISTPIGTGHQSLNLGLRKTFNLYANIRPCLSIPGHKTRY---NNVNTVVVRENTEGEYSGIENQPVKG-----------------------VAQSIKIITKEASTRIAHYAFQYALANGRKKVTCIHKANIMKQSDGLFVKSCREVSTRYPSIK--
21 UniRef50_P80046 Isocitrate dehydrogenase [N... 208 1e-52 1 54.8% 2:222 38:265 -GVDIWPATELVINAAIAKAYGGREEINWFKVYAGDEACELYGTYQIFPEDTLTAIKEYGVAIKGPLTTPVGGGIRSLNVALRQIFDLYTCVRPCRYYPGTPSPHKTPEKLDIIVYRENTEDIYLGIEWAEGTEGAKKLIAYLNDELIPtkKQIRLDSGIGIKPISKTGSQRLVRRAILHAKRLPKAkvTLVHKGNIMKFTEGPFRDWGYELATTEFRAECV
22 UniRef50_P50213 Isocitrate dehydrogenase [N... 207 2e-52 1 28.5% 1:221 42:227 IGPEISAAVMKIFDAAKA-------PIQWEERNV--TAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYT---DVNIVTIRENTEGEYSGIEHVIVDGVVQ-----------------------SIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKF-
23 UniRef50_B8N3I6 Tartrate dehydrogenase, put... 206 3e-52 1 23.6% 1:220 57:257 IGIEVVDAAIQVVEKLAKTL--GTFNIDFTHIPWGTAYYKEHGR--YVSEDCLDTLRKFDAGLFGAVGAPDVPDhwGLLLALRGPLQLYANVRPVRTFPGTKCPLNTaeGIDWMLVRENSEGEYSGQGGRSHVG-------------------QPWEAATEVAMFTRVGIERIMRFAFEVAQSRPRKLLTVVTKSNSMRNGMVLWDQVAAEVAKDFPDVT--
24 UniRef50_P28241 Isocitrate dehydrogenase [N... 205 1e-51 1 27.1% 1:221 47:231 IGPEISKSVKKIFSAA-------NVPIEWESCDVSPIFVN---GLTTIPDPAVQSITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTY---ENVDLVLIRENTEGEYSGIEHIVCPGVVQ-----------------------SIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTL-
25 UniRef50_B9KYU3 Isocitrate dehydrogenase (N... 204 2e-51 1 30.0% 1:220 31:218 IGPEIVESACRLIEAV-------GAPIEWEVRRAGASVFRE-GIASGVPDDTIESIKRTRVVLKGPLETPVGYGEKSANVTLRKLFEAFANVRPVRELPSVPTPYRG-RNIDLVVVRENIEDLYAAIEYRETPGVT-----------------------IAHKLISYKGSEKIIRFAFELARAEGRKKVTCATKSNILKLTEGWFQHIFEEIASEYPDIE--
26 UniRef50_A9QPI0 Isocitrate/isopropylmalate ... 204 2e-51 1 29.1% 1:220 14:200 IGPEIMDATLKVI-------LEAGAELEIEKIEIGFKVY-SMGNPSGIEPSSWESLKRTKVFLKAPITTPQGGGFKSLNVTVRKALGLYANIRPCISY--APFIHTKHPGIDLVIIRENEEDLYGGIEHRQGV-----------------------DSFQALKIMTRQGTERIIRYAFEYARCYGRKKVSSFTKDNILKITDGMFHKVFEEVAKEYPQIE--
27 UniRef50_O67480 Isocitrate dehydrogenase [N... 200 3e-50 1 49.3% 1:215 49:260 IGPEITQAMLLIINTAVEKTYNGSKKIYWVELLAGDKAEEKTGE--RLPQETLDVLKESIVGIKGPLGTPVGKGVRSINSALRRAFDYYSAVRPVYWM-GQATPIPNPERVDLVVFRENTDDVYAGVEFFAGTPEAKKVREFLIKEMGAKEEGFPEDVGITVKPMSEFKTKRHVRKALRYALENNKKNVAVIGKGNIMKATEGAFINWAFEVAEE-------
28 UniRef50_A9IDG2 Tartrate dehydrogenase n=5 ... 199 6e-50 1 23.2% 1:220 14:215 IGKEVIPAGRQAMQVLAET--DGSFTFEFQDFDWGGDYYRRHG--VMMPADGLEPLRDKDAILFGSAGDPdhITLWGLRLKICQGLDQYANVRPTRLLPGIDGPLKraEQLDWVIVRENSEGEYSGVGGRVHQG-------------------LPIEAATDVSMMTRAGVERILRYAFRLAQSRPRKQLTVVTKSNAQRHAMVMWDEIALEISREFPDVR--
29 UniRef50_P33197 Isocitrate dehydrogenase [N... 198 1e-49 1 32.9% 1:222 30:219 IGPECVEATLKVLEAAKA-------PLAYEVREAGASVFRR-GIASGVPQETIESIRKTRVVLKGPLETPVGYGEKSANVTLRKLFETYANVRPVREFPNVPTPYAG-RGIDLVVVRENVEDLYAGIEH-----------------------MQTPSVAQTLKLISWKGSEKIVRFAFELARAEGRKKVHCATKSNIMKLAEGTLKRAFEQVAQEYPDIEAV
30 UniRef50_B1I496 3-isopropylmalate dehydroge... 197 2e-49 1 26.9% 2:220 28:228 -GPEQVREGLKVLHAAAGK---EGFALETTVLDWGGEYYLRTGE--VLPPDAVEQLKRYDAIYLGAIGHppGILEKGILLRLRFELDQYINLRPVKLYPGVETPikGPEDIDFVVVRENTEGLYAGSG-------------------GFLKRGTPDEVAIQTSINTRKGVERCVRFAFEYCRKrgRRKVTLCGKTNVLTFAFDLWERVFNEVGEEYPDIE--
31 UniRef50_C6V444 Isocitrate dehydrogenase n=... 197 2e-49 1 28.2% 1:220 12:195 VGPEIMTSVLEII-------FEAGAEIQIDTIEIGQKIYEK-GWPSGISDSGWETLKRNKVLLKAPITTPRGGGVRSLNVTLRKKLGLFANIRPCKS-----HLEWQDPKMDIVIIRENEEDLYSGIEYR-----------------------QTLDTYNCTKVITESTSERICRYAFEYARSNGRKKVTVMVKDNIMKLTDGIFHKLFKKVALEYPDIE--
32 UniRef50_B3TCK6 Putative isocitrate/isoprop... 197 2e-49 1 24.4% 1:221 15:199 IGPEISESALSILEAINDNFP---LSLEIKKLEAGDAVLKNTGK--ALPDETFEAIKNSDACLKAPVG----ESAKDVIVYLRRMLDLYANIRPAKSYPNMPSL---RDDVDLVIVRENTEDLYTGEEFDIG------------------------DAAVAFRIISEKASKRIANYAFTIASKRKMKKVTCVHKSNVMKKTDGLFARTCSKVANDFPDVKF-
33 UniRef50_A5CDH3 Isocitrate dehydrogenase, N... 197 3e-49 1 29.4% 1:221 15:202 IGPEIMEAVVYVLKEAA-------VPLRLETIEIGEKLYNKY-YTYGITEDTWSQIFRTKALLKGPVTTPQGGGYKSLNVTLRKTLGLYANVRpcSYFPFVNT---SAPEIDVVIIRENEEDLYAGIEYHH-----------------------TADTYESVKLISRSGSEKIIRFAFEYALKNNRKTISCFSKDNIMKFTDGIFHKTFNEIASQYSNIQV-
34 UniRef50_UPI0001AF2578 isocitrate dehydrogenase [N... 197 3e-49 1 33.5% 2:219 15:224 -GPELVDAARSVLDHA---ARLSGFKIDWDVHQAGQRALAE--SESLLPDATLNSIRTNGAALKGPTTTPIGTGHRSVNITIRQELDLYACLRPVRSLPIASTQEEPERpvDLVVVRENTEDVYAGLEYPKGSPGARAVVQAL----GALGRPLPADTAVSLKPFTPHGCERVVEFAFNHAARHGRKLVESVCDARRYPATEGMFARVASKVAARHPSI---
35 UniRef50_O81796 Isocitrate dehydrogenase [N... 196 4e-49 1 29.1% 1:220 49:228 IGPLVTGAVEQVMEAM--------------HAPVHFERYEVLGNMRKVPEEVIESVKRNKVCLKGGLATPVGGGVSSLNMQLRKELDIFASLVNCINVPGLVT---RHENVDIVVIRENTEGEYSGLEHEVVPGVVE-----------------------SLKVITKFCSERIARYAFEYAYLNNRKKVTAVHKANIMKLADGLFLESCREVAKHYSGIT--
36 UniRef50_Q46NL2 Tartrate dehydrogenase n=12... 196 5e-49 1 21.4% 1:220 17:217 IGNEVVPEGIRVLEAASAKF---GFKLAFTTYDWSCARYHSQG--SMMPSDGIERLRDSDAIFLGAVgvPDHVSLWNLLIPIRREFDQYVNLRPVRLLPGVPCPlkKPGDIDFWIVRENTEGEYSQVGGRMFAG-------------------TEHEFVTQEAIFTRRGTDRIMRYAFDLAKKLGRNHVTSATKSNGIFHSMPFWDERFAAVGAEYPDIR--
37 UniRef50_P41564 Isocitrate dehydrogenase [N... 196 5e-49 1 21.7% 1:221 27:210 IGPELMLHVKSVFRHAC-------VPVDFEEVHVSSNADEEDIRNAIM------AIRRNRVALKGNIETNHnpSHKSRNNILRTSLDLYANVIHCKSLPGVVT---RHKDIDILIVRENTEGEYSSLEHESVAGVVE-----------------------SLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITF-
38 UniRef50_P51553 Isocitrate dehydrogenase [N... 195 9e-49 1 21.7% 1:221 65:248 IGPELMLHVKSVFRHAC-------VPVDFEEVHVSSNADEEDIRNAIM------AIRRNRVALKGNIETNHnpSHKSRNNILRTSLDLYANVIHCKSLPGVVT---RHKDIDILIVRENTEGEYSSLEHESVAGVVE-----------------------SLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITF-
39 UniRef50_A7SJV9 Predicted protein n=1 Tax=N... 194 2e-48 1 23.5% 1:221 61:250 IGPEMVVAVQDIFRHI-------GVPVDFEELNLSGLDIKDEDSYLGAFNEAITSIKRNGVAMKGNIFTPLdpGFRSLNLELRVHLDLFANIVRCKSIPGIQT---RHNNVDLVIIRQNTEGEYSHLEHENVSGVIE-----------------------NLKVTTEEACMKIAQYAFDFAEKHDRKKVTAVHKANIMKMGDGLFLRCCEEMSHSYPNIEF-
40 UniRef50_O29627 3-isopropylmalate dehydroge... 194 3e-48 1 23.6% 1:220 12:191 IGKEVMEAAMLILEKL-------DLPFEYSYYDAGDEALEKYGK--ALPDETLEACRKSDAVLFGA----AGETAADVIVRLRRELGTFANVRPAKAIEGIECLYP---GLDIVVVRENTECLYMGFEFGFG------------------------DVTEAIRVITREASERIARYAFELAKREGRKKVTALHKANVMKKTCGLFRDVCREVAKDYPEIQ--
41 UniRef50_D2EFL9 3-isopropylmalate dehydroge... 192 6e-48 1 31.8% 1:220 16:204 VGPDVINASLLVLDAVKKKF---NLDIEYVPAVAGLNTVEKYGTN--LPKETLDTLKETDCVLKGPTTTPEGAnlPSANVGIRKYFDLYADVRPNKTLPNVPSI---KPNVDMVIVRENTEGMYSGLDFRVN-----------------------QETTIGIRVITRKACERIVKYAFKLAESR-KKHVTLVHKGNVLKVSDGMFKDIFYEEAKKHPDVK--
42 UniRef50_Q0BQF4 Isocitrate dehydrogenase (N... 192 7e-48 1 31.9% 1:216 23:207 IGPEIVESVVSVLDAL-------GSPFEWDSQYAGMAAIARVGDP--LPRETIQSIHHNKLALKGPLTTPTGGGYRSVNVQLRKEFELFANVRPALTL----IPGGRFENVDITLIRENLDGFYAAFEHYMPIGD------------------DPHAVAMCAGFNTRTGCHRIIRYAFEYAMQNGRKKVTLVHKANILKALTGIFLEAGKEIAKEY------
43 UniRef50_A7T3D9 Predicted protein n=2 Tax=c... 191 1e-47 1 73.8% 1:183 39:221 IGIDISPVMIKVVDAAVQKAYGGERKISWMEVYAGEKATQVYDQDTWLPQETLDAVKDYVVSIKGPLTTPVGGGIRSLNVALRQQLDLYVCLRPVRWFEGVPSPVKKPGDVDMTIFRENSEDIYAGIEWKAGSPEATKVIKFLKEEMGVTKIRFDQDCGIGVKPVSKEGTKRLARKALHSAEA---------------------------------------
44 UniRef50_C4QCG1 Isocitrate dehydrogenase [N... 191 1e-47 1 24.4% 1:221 79:258 VGPELLSYVKEVFQVI-------GAPIDFEEVAVNQESEDATFT------DALLAMKRNGVGIKGNFATEPGQS--SRNVALRLNLNLYAFVQRCRNFPGVVT---RHQNVDIVIIRENTEGEYSRLEHENVPGVVE-----------------------SLKIITREKSTRIAQFAFDYAVRHNRKKVTAVHKANIMKLGDGLFLDVCSSIAKNYPQIEF-
45 UniRef50_A4IK21 Tartrate dehydrogenase n=7 ... 191 2e-47 1 20.4% 1:221 14:215 IGPEVMNEALKVLRILKDKDYTFQFHADM--FLWNSEYYLQHGR--MMPENGLDILKNYDAILFGAIGDpdDISVWELIMPIRKRFCQYVNLRPVKKLKGIPEQFIHQEriNFVIVRENAEGEYSNSGGRIYQG-------------------TDQEIAVQNTIITRKGTERIARYAFQYAKKHGYQKVINATKSNAVVHSMKLWDEVIEHVASEYPDIQL-
46 UniRef50_Q1RJU4 Isocitrate dehydrogenase [N... 190 3e-47 1 28.8% 1:219 15:200 IGPEIMEAVLYILRKAEAR-------IRLETIEVGEKLYVKH-YSSGISEQSWESIERTGVILKAPITTPQGGGYKSLNVTIRKTLQLFANIRPSVSF--YPFTKTLHPNLNLTIIRENEEDLYAGIEYR-----------------------QTHNMYESVKLISRTGCEKIIRYAFEYAVKNNRKKVTCLSKDNIMKFSDGIFHKVFNEIAKEYPQI---
47 UniRef50_UPI0001B4F4BD putative isocitrate/isoprop... 190 4e-47 1 24.0% 1:221 18:216 IGPEVVAATVPALRAALE---ADGHRLDVTSFDWGGERYLRQG--AAMPPDAADLVKKTDAVLFGAVGRPDVPEhwGLIIGLRQQLDLAVNLRPVRAFPGVPTKVRDTDGVDLVIVRENTEGEYVGAGGVAHAG-------------------SGHDLGIEVAVHSRRAIERAAHQAFALAGRRS-GRLCLVTKSNAMRYGYPLWDRVVREVGEQYPGVEL-
48 UniRef50_O27441 3-isopropylmalate dehydroge... 189 4e-47 1 26.8% 1:220 14:193 IGVEVMEAALHILNTL-------DLDLEFIHADAGDACLKRTG--TALPEETLEAVGEARATLFGA----AGESAADVIVRLRREFDLFANLRPVKSLPGVPCLYP---DLDFVIVRENTEDLYVGDE------------------------EYTPEGAVAKRIITRTASRRISQFAFQYAQKEGMQKVTAVHKANVLKKTDGIFRDEFYKVASEYPQME--
49 UniRef50_B3RY01 Putative uncharacterized pr... 189 5e-47 1 21.7% 1:221 98:277 IGPEMARHVKTVL-------HKCGAPIDFEVIDIKDESS---------TDAAIISLKRNGIGLKGTITTnsNPQSQSINAQIRRKLDLYSNIVPCKSIPGV---WTRHGQVDLVVIRENTEGEYGSLEHENVDGVVE-----------------------SLKIITEKKSRRIAKFAFDYALQNNRRKVTAIHKANIMKLADGLFLETCREISKDYTDIEF-
50 UniRef50_Q0ZQ44 FrbE n=1 Tax=Streptomyces r... 189 6e-47 1 34.4% 2:219 15:219 -GPELVAAARTVLDTA---AGSAGFHLDWDVRPAGQGALRSVGE--LLPASTLDSIRRNGVALKGPTTTPIGVGHRSVNITIRRELDLYACVRPVRVWPGAG---AVDSGIDVVVVRENTEDVYSGLEYPADSDGAAVVSATLSEFGHA-----DPGIAFSLKPITPGGSRRIVAFALDHARKNGRRKVEVGADVYRYPRTEGLFFEAARELGPEYPDI---
51 UniRef50_D0DDG4 3-isopropylmalate dehydroge... 189 7e-47 1 20.8% 1:221 14:211 IGVDVTDAAMEVLGAAAK----GRFAFDTTSFPWSCEYYLEHGR--MMPEDGIETLRGFDAIYLGAVGWpdSVSLHGLLLPIRKAFNQYANIRPHRLLAGVEGPLK-AEGFDILCIRENTEGEYSGAGGRVHEGK-------------------GNEVAVETSVFTRAGVERILRFGFEQARSR-RGHLTSVTKSNAQKYSMVFWDEVTRELAAEYPDVTV-
52 UniRef50_Q4QLS3 3-isopropylmalate dehydroge... 189 7e-47 1 22.6% 1:221 14:220 IGPEVMAEAMKVLNKVQEKF---GFKLNFNEFFVGGAAIDHCGYP--LPAETLKGCDEADAILFGSVGGPKWTNlrGALLPLRKHFKLFCNLRPATLYKGLecPLRaaKGFDMVVVRELTGGIYFGQPKGREGEGSQTK-------------------AFDTEVYYKYEIERIARAAFEAAMKRN-KKVTSVDKANVLQ-SSILWRETVTEMAKDYPEVTL-
53 UniRef50_D1B6F8 3-isopropylmalate dehydroge... 188 1e-46 1 26.9% 7:218 24:238 ------DSGFDMMEGALVVLLSMDLPIDWVRADLGWCMWEkqGDpnTVPPETIDKIRSSDATLMAAITSKSgkGFKSAILQMRQLFDLYINLRPAKTLPDLGSPLKGDPKIDLVLFRENTEDLYSAVEFHPLPEEMFNLHK------GMERFRKMGDVAVSWRVFSSVGCERIIRAAFEYAKSTGRTKVHCCNKANVIRETDGMMKRIFLEVAKEYEQ----
54 UniRef50_Q51945 Tartrate dehydrogenase/deca... 187 2e-46 1 19.6% 1:219 16:217 IGLEVLPEGIRVLEAAALK---HGLALEFDTFEwsCDYYLQHGK--MMPDDWAEQLKQYDAIYFGAVDWPdhISLWGSLLKFRREFDQYVNIRPVRLFPGVPCAlrKVGDIDFVVVRENTEGEYSSLG-------------------GIMFENTENEIVIQESIFTRRGVDRILKYAFDLAEKRERKHVTSATKSNGMAISMPYWDKRTEAMAAHYPHV---
55 UniRef50_Q0W5L4 3-isopropylmalate dehydroge... 187 2e-46 1 20.9% 1:220 14:238 IGPEVIAEGRKVIAAAQEVY---NFDVEWIDMPFSADHYVKTGE--TISESSLKELSKYRAIFLGSIGdkPGVLEKGILLTMRFYYDQYVNLRPVKLMEGVETPLktAADIDFYVVRENTEDFYVGIGGRSKKGTSKQELEVIRqkFGLDVETDSDEIAYQLGVVSKEGAKRIIEYSFDLANSRPKKHLSSVDKANVLTDIYGFWREVFTDTAAKYPDVK--
56 UniRef50_D2Y061 Isocitrate dehydrogenase n=... 187 3e-46 1 24.1% 1:220 67:249 IGPECMGYVRDIFKYI-------GAPIDFEVVDI-----DPTMDNDDDVQYAITTIKRNGVGLKGNIETKSEAAytSRNVALRNELDMYAYILNCKSYPGVAT---RHKDIDVVIIRQNTEGEYAMLEHESVNGVVE-----------------------SMKVVTADNSERVARFAFEFAKKNGRKKVTTVHKANIMKLSDGLFLETSRRLAKEYPDIE--
57 UniRef50_Q6W109 Tartrate dehydrogenase n=13... 187 3e-46 1 19.5% 1:221 14:212 IGQDVTDAAWQVLSTVARH---SGFTLTATPFPWSCAFYKETG--AMMPPDGIETLRRFDAILLGAVGWPAEvsLHGLLLPIRKAFVQYANIRPHRLLSGVKGPLK-AEGFDILCIRENTEGEYSGAGGRVHQGTA-------------------DEVAVETSIFTRTGVERILRFGFDQARQR-RRKLASVTKSNAQKYSMVLWDEITRELAAEYPDVEV-
58 UniRef50_A6WAX5 3-isopropylmalate dehydroge... 186 4e-46 1 26.0% 1:219 34:232 IGPEIVPASVKILDAAVAAAGAT--PIAWTELPLGRSAIDEYGEHT--PTKTLDALDEVDGWLLGPHDSAAYPEPynPSGTIRKHFGLFANIRPAKAFRG---GNAIVEGTDLVIVRENTEGFYADRNTFAGTGEM----------------MPTPDVAIMHGIITRAATERIAHEAFQLARTRD-KRVTIVHKANVLKMTTGLFRDVCREVGKQYPDV---
59 UniRef50_Q5P9Q1 Isocitrate dehydrogenase n=... 186 4e-46 1 27.3% 1:220 18:204 VGPEIMEAVLFILKEARA-------DVSIETVDIGHNQYKKEWTSGIAP-SAWESISRTRLLLKAPTMTPQGSGHKSLNVALRQRLGLYVNVRPCVSY--FPVVGTKHPDLDVVIIRENEEDTYSGVEHK-----------------------LSEDTHECVKISTRSASEKICAYAFNYARAHNRKKVTCFVKDNIMKMTDGILHASFDKVAKGYPDIE--
60 UniRef50_D0LNY3 3-isopropylmalate dehydroge... 185 7e-46 1 23.3% 1:219 20:240 IGPEVMAQARDLLEAVAE---PSGVRFELDEIPCGGRFYLEHGARDW-PEDAEARCRGADVILLGAVGWPSPDGphSAVIGNRVDLDLYANVRPVKLLPGVAHRIsrPEHVDMVILRENTEGLYAGMGGQLRVGGSAS-------------------VATDTRLITRRGCERIIRRAFELCEQRGrkRVTGIVKHNVLE-GCKLFAEVFAEVASEYPDI---
61 UniRef50_O43837 Isocitrate dehydrogenase [N... 184 1e-45 1 22.6% 1:221 59:245 VGPELMHAVKEVFKAAA-------VPVEFQEHHLSEV---QNMASEEKLEQVLSSMKENKVAIIGKIHTPMegELASYDMRLRRKLDLFANVVHVKSLPGY---MTRHNNLDLVIIREQTEGEYSSLEHESARGVIE-----------------------CLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKF-
62 UniRef50_Q2JYV7 Probable tartrate dehydroge... 184 1e-45 1 19.5% 1:221 14:212 IGRDVTDAAWAVLE---KTAGSGGFSLEATRYPWSCDYYLENG--SMMPADGIETLKSFDAILLGAVGWpdSVSLHGLLLPIRKAFVQYANIRPHRLLPGVQGPLRS-DGFDILCIRENTEGEYSGAGGRIHQGA-------------------DNEVAIETAIFTRKGVERILRFGFEQARAR-RGKLASVTKSNAQKYSMVFWDEITHGLSAEYPDVEV-
63 UniRef50_B7PN53 Isocitrate dehydrogenase, p... 184 3e-45 1 22.6% 1:221 58:241 IGPEMMRHVEAIF-------ACGKVPVDFETIIVDANV----GDASSM-DHAIKSIRRNGVALKGNitTSYSMTVEPRNLLLRNKLELYVNVVHCRNHPGINT---KHKGVDIVVIRQNTEGEYSCLEHEVTSGVVE-----------------------SLKIITWAKSFQIAKYCFEYARTHMRKKVTVVHKANIMKLTDGLFLKTCTEVAQEYPDIEL-
64 UniRef50_B0ER68 Tartrate dehydrogenase, put... 183 3e-45 1 23.6% 1:220 21:213 IGVEVMSEAEKMFQSL-------NLPIQRDYVDWGIQHYLKTGK--VVPIDYIDQVKQYDAILLGSLGDppDYVTLEPLIQMRQQLDQFLCLRPAKHFPGIPTPLKKCE-IDILVVRENSEGEYSNIGGIFKSG-------------------TPDEFAIESAVHTRRGLERVIRYAFEASRKR-RNHVTLATKSNAMKYGMVLWDSVFEAIAMEYPDVT--
65 UniRef50_P42958 Probable tartrate dehydroge... 183 4e-45 1 22.3% 1:220 16:214 VGKEVVAAAEKVLHTAAEV--HGGLSFSFTAFPWSCDYYLEHGK--MMPEDGIHTLTQFEAVFLGAVGNpdHISLWGLLLKIRRELELSINMRPAKQMAGITSPLLHPNDFDFVVIRENSEGEYSEVGGRIHRG--------------------DDEIAIQNAVFTRKATERVMRFAFELAKKR-RSHVTSATKSNGIYHAMPFWDEVFQQTAADYSGIE--
66 UniRef50_A5UMS5 3-isopropylmalate dehydroge... 183 4e-45 1 25.6% 1:219 21:200 IGKEVMEATISVLDEL-------DVDFDYIYGIAGDECNEEHGTP--LPQETIDIVRDSDACLFGA----AGETAADVIVKIRQEMKMFANLRPVKSYPNTKSLF---ENVDFMIVRENTEGLYIA-----------------------DQEEETEDGAIAKRVITREAEERIIDYAFQYAKDNNRTKVTAVHKANVLKKTDGLFKKIFYEVGEKYPDI---
67 UniRef50_UPI00019260EC PREDICTED: similar to predi... 183 5e-45 1 22.8% 16:221 64:240 ---------------IVEVFQNSGVPVDFEECYITGDTNEEKMKSF---NDIKTSVLRNGTALKGNWATSMGIDSKSYNVLLRHDLDLYANVVKFKSYP---TVITRHNNVDLIVIRENTEGEYTNLEHENIPGVIEM-----------------------IKIITKKKSERIAKYAFDYAMENNRKKVTAVHKANIMKLSDGLFLKVCKEVAEGYPEIDF-
68 UniRef50_Q46FW0 3-isopropylmalate dehydroge... 182 6e-45 1 23.4% 1:218 11:196 IGREIIPAAVKVLDA-------FGLEFEKVPLELGYTRWERTG--TAISNNDLETIKGCDAVLFGAITTVPDPNYKSVLLTIRKELDLYANVRPVKPLPGI-TGVTGRNDFDFIIVRENTEGLYSGIE------------------------EIGPELSWTKRVVTRKGSERIAEYACKLAKKR-KNKLTIVHKSNVLK-SDKLFLDVCRQTAseYED----
69 UniRef50_Q8XSY8 Probable 3-isopropylmalate ... 182 7e-45 1 22.6% 1:221 11:213 IGPEIVGAAMEVLRSADSVF---KLDLAFDYDDVGFTSLEKYG--TTLRDEVLAKAKTYDGVILghADYppDKGGRNVSAGFRIGLDLYANVRPARTRPFLTSNMREGRTMDLVIMREATEGFYPDRNMTKGWAE----------------LMPSPDMAISLRKITRHCSERIARRAFELAMKR-KKKVTAIHKANSFHMTDGLFLECVRDVARDFPEVRL-
70 UniRef50_Q58991 Homoisocitrate dehydrogenas... 182 7e-45 1 24.5% 1:216 12:203 IGKEVIPEAIKILNELGE--------FEIIKGEAGLECLKKYGN--ALPEDTIEKAKEADIILFGAITSPKPgnYKSPIITLRKMFHLYANVRPINNfkIADYEFLNAKNIDIVIIRENTEDLYVGRE------------------------RLENDTAIAERVITRKGSERIIRFAFEYAIKNNRKKVSCIHKANVLRITDGLFLEVFNEIKKHY------
71 UniRef50_B0RIP4 3-isopropylmalate dehydroge... 182 8e-45 1 25.3% 1:221 15:217 IGPEVVHEALRVLREAV----PADVSLDTTQYPFGAGHFLETGQ--ILTDSDLAALAQHDAILLGAVGGDPRDaeRGLLLKLRFAFDHYINLRPTALLPGVASPLAAPGQVDFVVVREGTEGPYAGNG-------------------GVLRRGTEHEIATEVSVNTAHGVERTVRFAFELAEKRDRKRVTLVHKTNVLTFAGSLWQRTVDRVAAEHPDVTV-
72 UniRef50_UPI0001C310FF Tartrate decarboxylase n=1 ... 181 2e-44 1 24.0% 1:221 11:207 VGPEVMAEARKALDALE-------LGIAWTDVPWGSAWWAEHG--TMMPADAIDVLRGHDAILMGAVGDPAVPdlWGLILKIRQELDLWVNVRPARLLEGIPGPlrAPHDVDMVFVRENSEGEYAGVGGRVHRG-------------------FGHDVAIESSVFTRRGCERVIRYAFGMASAR-KGVLVNATKSNASRFGFPFWDEIVAEVGAEFPGVVV-
73 UniRef50_A5US63 Homoisocitrate dehydrogenas... 181 2e-44 1 26.2% 1:221 16:216 IGREVIPAAVAVLRA-------TGLPFHFENADAGWECFQRQGE--ALPSATLTAARAADAILFGAVASppVAGYRSPIVRLRRELDLYANIRPVFDDLPENGSNPRRRKVDLVVVRENTEDVYAGRERVEDDGA----------------------TAIAERVITRRASARIMRVACDLARArpPGRVTVVHKANVLRETCGLFRSVALEVAQAYPDLQI-
74 UniRef50_O13696 Isocitrate dehydrogenase [N... 181 2e-44 1 27.3% 1:216 31:213 IGRETSNAVTEIFKTA-------NVPIEFEEIDVTGMEKNNKSSGDAL-HEAIQSLKRNKVGLKGILFTPFegGHTSFNVALRKELDIYASLVLIKNIPGFKT---RHDNVDFAIIRENTEGEYSGLEHQSVPGVVE-----------------------SLKIITEYKSKRIAQFAFDFALQNGRKSVTCIHKANIMKLADGLFRRTFYDVANGY------
75 UniRef50_Q47WG3 3-isopropylmalate dehydroge... 180 2e-44 1 20.8% 1:221 12:218 IGPEVMVEAKKVLNTVASKF---DFEITTQDYDIGGAAIDNHGN--ALPDSTMAGCIESDAILFGSVGGPKWANlrCALLGLRSHFDLFCNMRPATLQPALSSLSTLRSDidVLVIRELTGDIYFG-------------------EPKGRRGEGEEETGFDSMFYSRREVKRISHLAFQAAQKRN-NKVTSVDKANVL-ATSQLWRQVVEEVAVEYPDVEL-
76 UniRef50_A5FXZ9 3-isopropylmalate dehydroge... 180 2e-44 1 24.1% 1:220 11:208 IGHEIVPEAVRVMQAAAAR---TGLAIEWQDIPIGRAALDSLG--STLPDGTIERLDALDGWLLGPIGhpKIPEAINPHPLLRKHFDLFANIRPVKSHAALPCL---HQGVDLVIVRENNEGFQPDRNVVAGSGE----------------FRPTPDVTISVRVITRNGSSKVARAAFELARAR-RRHLTAVHKDTVFKLGCGMFAEECRRLAAEYPDVT--
77 UniRef50_C9KJM9 3-isopropylmalate dehydroge... 180 3e-44 1 20.4% 1:221 13:217 IGKEITDSAVEVLEKVDEKF---GLGLSYTYKDAGGTAYDKFGTP--LPDDTIEACKASDGVLFGAVGGDKWDnpEKAILGLRKNLGLYANLRPVKVADAlpLKPELVKGVDLVIVRELIGGIYFGDKCE-------------------SEQHNGAERAWDLENYSVPEVDRIAKLAFETAKLR-RGKVTSVDKANVL-ATSRLWRRTVAKVAESYPDVEL-
78 UniRef50_D1HRU7 3-isopropylmalate dehydroge... 178 1e-43 1 19.9% 1:221 154:359 IGPEVISVAKNVLKLAGSL---EGIEFGFQEMPVGGCALDLTGVP--LPEETLLVAKQSDAVLLGAIGGYKWDspETGLLQLRSGLKVFANLRPASVLPQLvlKKEVAEGVDLMVVRELTGGIYFG------------------KPRGFSKNENGEEIGFNTEVYATYEIDRIARIAFETAQKR-RGKLCSVDKANVLEASM-LWRKRVTAMASEYPDVEL-
79 UniRef50_P28834 Isocitrate dehydrogenase [N... 177 2e-43 1 23.1% 1:221 39:222 VGKEITDSVRTIFEA-------ENIPIDWETINI-----KQTDHKEGV-YEAVESLKRNKIGLKGLWHTPAdtGHGSLNVALRKQLDIYANVALFKSLKGVKTRIP---DIDLIVIRENTEGEFSGLEHESVPGVVE-----------------------SLKVMTRPKTERIARFAFDFAKKYNRKSVTAVHKANIMKLGDGLFRNIITEIgkEYPDIDV-
80 UniRef50_A1WHK9 3-isopropylmalate dehydroge... 177 2e-43 1 23.1% 1:221 11:210 IGPEIMAVAVRVLEAASKRF---QLDLEIGHDIAGHASLQRHG--ATVTPALLEKVKAADGLMLGPMATYdaKGEINPSKFFRKELDLYANIRPARTFPGMAHRV---GEFNLAVVRENTEGFYADRNIESGSSEML----------------ITPDTVISLRRITRLCCERIARSAFDLARTRAR-HVSIVHKANVLKIGDGMFVDICRQVAREFPQVRV-
81 UniRef50_Q9U6V3 Isocitrate dehydrogenase ga... 177 2e-43 1 23.5% 1:221 55:240 IGPEMLDIVQKIFTFA-------NVPVDFEECQLDSKPT----SPESDLDNAIMSIQRNGVAIKGNIEtyDDPIFKSRNVELRRRLDLFANVLHCVSIPTIPT---RHKGINIVMIRENTEGEYSGHEHETVNGVVE-----------------------SLKICTREKLERISRFAFDYAIAHNRKKITAVHKANIQKLADGLFLKVVGEIakEYPSITF-
82 UniRef50_O15384 NAD (H)-specific isocitrate... 177 3e-43 1 22.7% 28:221 1:164 ---------------------------DFEEVHVSSNADEEDIRNAIM------AIRRNRVALKGNIETNHnpSHKSRNNILRTSLDLYANVIHWKSLPGVVT---RHKDIDILIVRENTEGEYSSLEHESVAGVVE-----------------------SLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITF-
83 UniRef50_B1MJY2 Tartrate dehydrogenase n=5 ... 177 3e-43 1 22.5% 1:218 15:209 IGVDVTREAVKVMDSA------TGGRIEWTEFDYSCERYAKTG--AMMPPDAPTTLAGFDAILLGAVGYpdDVSLWGLLIPLRRAFNQYVNLRPVRLLPGIASPLasDEALSMVIVRENTEGEYSPIGGVHNRGNQ-------------------NEFALQESVFTRIGCERIIRYAFELAASAGF-RVCSATKSNGIIHSMPYWDSIFNEIAAEYPQ----
84 UniRef50_A9FME3 3-isopropylmalate dehydroge... 176 5e-43 1 22.5% 3:220 19:218 --PSVIAEAKLLLELYQERA---GLPIDLWELDLGADRYLRDG--TTFPNQIQIAirECSAVLLGALGDPRVPnaRDILFGMRFGYDLYANVRPVRALSdvPLKGRTAKDIDFVVFRENTEGIYVGMGGQFKRG-------------------TPDEVAINEDVNTRKGVERIIRAAFDYARANGRTRVTMADKSNAMRHAHELWLRVFHEVRAQYPEIQ--
85 UniRef50_Q47SB4 3-isopropylmalate dehydroge... 175 6e-43 1 24.4% 1:221 16:217 IGPEVVAEGLKVLSAVAPR---HGLTLDTTEYELGAQRWHATGE--VLPDAVEEELRQHDAILLGAVGDPTVPseRGLLLRLRFNFSHYVNLRPVRLYPGVTTPLAgpEDIDMLVVREGTEGPYAGMG-------------------GVLRKGTPHEIATQDSVNTRLGVERVVRYAFAKAAERPCHKLTLVHKDNVLTYAGELWQRVVREVGAEYPQVEV-
86 UniRef50_D2VFR4 Homo-isocitrate dehydrogena... 175 6e-43 1 24.1% 1:220 42:241 IGKEVVPAAVQVMNAAIAKNVKadFSLQYIPLEAGWETFQKTGKS--LPVETVEALkkCDGAIFGSVQSPSHkgYSSPIVAMRKLVDLYANIRPCQDL---------AKGIDMLIVRENTECLYIKKEKLTVDPT------------------TGEKTAVADRLITERASKRIAEIAYKLAVQRNkpKVTIVHKSNVLSVSDGLFRESCLEISKKYPQVK--
87 UniRef50_Q9WZ26 3-isopropylmalate dehydroge... 175 7e-43 1 23.1% 1:221 11:213 IGPEVVREALKVLEVVEKK---TGKTFEKVFGHIGGDAIDRFGEP--LPEETKKICLEADAIFLGSVGGPKWDDliGGLLALRKMLNLYANIRPIKVYRSLVHVSPLKegVDLVTVRELSYGVYYG-----------------------QPRGLDEEKGFDTMIYDRKTVERIARTAFEIA-KNRRKKVTSVDKANVL-YSSMLWRKVVNEVAREYPDVEL-
88 UniRef50_D0J9Z6 3-isopropylmalate dehydroge... 174 2e-42 1 20.4% 1:221 13:213 IGPEVIKQAIKALNSIGNRFH---HEFSYQNVLAGAKAIETFGDP--MPKETIDSCLKSDAVLFGSIGDPKYDspEDGLLKLRKEMDLYCNIRPIVTYPGipIKERKLEGVNFVIYRELTGGIYFGKKGRSKNG----------------------KEAYDYCVYSEKEIERIGEMSFKAARSRNRK-MTLVDKANVLE-TSRLWREVIQKMALDYSDVDL-
89 UniRef50_B0BZF3 Isocitrate dehydrogenase NA... 174 3e-42 1 30.8% 11:221 16:213 ----------QVTNALQMAIAATGVDITWQIVDIGGE-----DQQGLLPNYIFDIIRTAKTAVIGPLMMP--DNYRQMEADIREKLDLYVNLRPAKTMVGIPSNYQ---NVDIMIVRETTEGIYAGIEFERTSVEAADARSFLSKLSG---KRIREDAAVGIKPISVKGCGQIIEFAFNYARKTKRHQVIAVHQAHFMAHTDGLFLEIARDIAQEFPDIAF-
90 UniRef50_Q5SIY4 3-isopropylmalate dehydroge... 173 3e-42 1 21.3% 1:221 11:211 IGPEVTEAALKVLRALDE---AEGLGLAYEVFPFGGAAIDAFGEP--FPEPTRKGVEEAEAVLLGSVGGPKWDgpETGLLSLRKSQDLFANLRPAKVFPGlpLKEEIARGVDVLIVRELTGGIYFG-----------------------EPRGMSEAEAWNTERYSKPEVERVARVAFEAARKR-RKHVVSVDKANVLEVGE-FWRKTVEEVGRGYPDVAL-
91 UniRef50_Q6GF15 3-isopropylmalate dehydroge... 173 3e-42 1 18.6% 1:221 13:211 IGPEILNGSLSLLEIISNKY---NFNYQIEHHEFGGASIDTFGEP--LTEKTLNACKRADAILLGAIGGPKWtrPEQGLLKLRKSLNLFANIRPTTVVKGapLKAERVEGTDLVIVRELTSGIYFG-----------------------EPRYFNNHEALDSLTYTREEIERIVHVAFKLAASR-RGKLTSVDKENVL-ASSKLWRKVVNEVSQLYPEVTV-
92 UniRef50_Q5SIJ1 Homoisocitrate dehydrogenas... 173 3e-42 1 22.6% 1:221 13:198 IGHEVIPAARRVLEA-------TGLPLEFVEAEAGWETFERRGTS--VPEETVEKILSCHATLFGAATSpkVPGFFGAIRYLRRRLDLYANVRPAKSRP----VPGSRPGVDLVIVRENTEGLYVEQERRYL------------------------DVAIADAVISKKASERIGRAALRIAEGRPRKTLHIAHKANVLPLTQGLFLDTVKEVAKDFPLVNV-
93 UniRef50_Q4ZRW7 3-isopropylmalate dehydroge... 173 4e-42 1 20.5% 1:219 18:235 IGIEVMEAALPVIAAL-------NLPFDLVPADIGWQCWRAEGE--TVPARTWEIMASCDATLLGAITSKPLAEAesPVIQLRQNLDLYANVRPVTDMTG-------ENRFRFVVIRENTEGLYAGLDFGCIPDALVPLLEEREALGAAWQREGQDDATVTLRLQTRSGLMRIFEYAFEYARKNHFTRVTFVDKPMVLRHSSAFARGIFEATAQRYPDV---
94 UniRef50_A3P147 Tartrate dehydrogenase n=59... 173 4e-42 1 18.7% 1:219 51:251 IGVEVMPEGLRALDAVSRRF---GLRFAYEPIEwsCDYYAKHGQ--MMPDDWKTQLSGMDALLFGAVGWpdHISLWGSLIKFRREFDQYVNLRPARLFDGVPCPlrKAGDIDFMIVRENTEGEYSAVGGTMFEG-------------------TEREFVVQQAVFTRHGTERVLKFAFELAQRRA-KRLTVATKSNGIAISMPWWDARAAEMAARYPDV---
95 UniRef50_Q9FMT1 3-isopropylmalate dehydroge... 172 5e-42 1 20.8% 1:221 57:262 IGPEVISVAKNVLQKAGSL---EGLEFDFKEMPVGGAALDLVGVP--LPEETFTAAKLSDAILLGAIGGYKWdrPEMALFYLRRDLKVFANLRPATVLPQLvlKKEVAEGVDMMIVRELTGGIYFG------------------EPRGITINENGEEVGVSTEIYAAHEIDRIARVAFETARKR-RGKLCSVDKANVLDAS-ILWRKRVTALASEYPDVEL-
96 UniRef50_A9KQX3 Isocitrate dehydrogenase (N... 172 5e-42 1 29.1% 1:220 52:243 IGPAITSQAQRILEYLLKDDILQG-KVEFKVID-GLTIERRAAEHAAIPAEVLKELKECHVILKGPTTTppWPNVESANVAMRKELDLFANVRPVRIPE---------QGIDWTFYRENTEGAYA---------------------VGSKGIHVTEDLGVDFTVVTSGGSERIIRAAFEYAKANGKTRVTAVTKANIIKTTDGKFLDIFREIAKDYKDIT--
97 UniRef50_C3MI61 3-isopropylmalate dehydroge... 172 6e-42 1 22.0% 1:218 18:219 IGREVMPACLELVNAA--TTMAGAPALAFQTHNAGAQYYAESGD--ALPASTLDACRKSDAILFGAMGWppDGTEIIPQLDLRMELGLFAGVRPIRWFPGLPRVLTDpeQIDFVLVREQTEGLFYARG---------------------RGEIRNDEEAYDTMQITRSGTQRVTEFAFDIARQRKrgNVTCVDKANVFQ-SMAFFRKVFDEVADRHSD----
98 UniRef50_A9UQS3 Predicted protein n=1 Tax=M... 172 6e-42 1 26.2% 1:214 44:232 IGREIVSAAKECIEA-------TGVNIRWEQMDMGYEAMQNTG--VYIDDSHMDAFEEIGVLFKGPLTVPpgKRYTSGNQVFRKYFQLFANVRPVRSMPGVRAPF---NDVDLVVIRENTEDVYTGEETWVDA-----------------------DTVHCVKRISRGASERVADFSFKYARDNQRKRVTALHKANVCKQSDGLFLNTFHERAA--------
99 UniRef50_D0RN50 Threo-isocitrate dehydrogen... 172 9e-42 1 18.6% 1:220 14:213 IGPEIAKASVDVLQAALKLY---DLKVNLVYEEIGFASLKKH--KTTFRSEVLKIAEKCDGMILGTCShpTEEGGLNPSGVIRKYFDLYANVRPAKN--RLGKLERFPMGIDCLVMRENTEGFYSDRNMFKGVGE----------------LMPTPDVAISIRNITRKGSTRIAEIGFKYAMER-RKKLVAIHKANVLRYSDGLFLECARQVSKKYPEVE--
100 UniRef50_Q5HMF8 3-isopropylmalate dehydroge... 170 3e-41 1 20.4% 1:221 13:211 IGPEILSGTLELLKLISEKYH---FEYHLESHHFGGVSIDYYGTP--LTNETLQSCKNADAILLGAIGGPKWtrPEHGLLKLRKSLNLFANIRPTFVTKGAssPLKQdeGTDLVIVRELTSGIYFGEPSYVKKTE-----------------------ALDSLKYSSQEIERIVRIAFNLANRR-RKKLTSVDKENVL-SSSKLWRQIVNDVKKDYPEVEV-
101 UniRef50_Q5LAB4 3-isopropylmalate dehydroge... 170 3e-41 1 16.4% 1:220 13:212 IGPEISVQGVEVMSAVCEKF---GHKVNYEYAICGADAIDKVGDP--FPEETYRVCKNADAVLFSAVGDPKFDnpEQGLLAMRKKLGLFANIRPVQTFKClpLRAELVEGADFLCIRELTGGMYFGEKYQ------------------------DNDKAYDTNMYTRPEIERILKVGFEYAMKR-RKHLTVVDKANVL-ASSRLWRQIAQEMAPQYPEVT--
102 UniRef50_D2SEJ6 3-isopropylmalate dehydroge... 170 4e-41 1 25.8% 1:221 11:206 IGPEVVAEGLKVLRAVA-------PDVESTPYDLGASRWQRTGE--LLPDTVLDELRRHDAILLGAIGDppGILERGLLLRLRFELDHHVNLRPARLFDGVRSPLAAPGAIDMLCVREGTEGPYVGNG-------------------GVLRRDTPHEVATEVSLNTAFGVERVVRYAFERALARPRRHLTLIHKTNVLTHAGSLWSRTVEEVSAEFPEVTV-
103 UniRef50_UPI000186E03D isocitrate dehydrogenase, p... 169 6e-41 1 23.1% 1:221 48:232 IGPEIMDHTLRVLKAA-------GAPLSYEIFALSS----KDGSKNNDFDEALTSIRRNRVALKGNIeqSKNPHIKSRNIIFRKTLDLFVYILFCKTFPGLS---NKFGEIDITVIRQNTEGEYLMLEHEPRTGSVE-----------------------SLKVLTRFNLERLIEFAFDYALTNDRKLITVVHNANIQKLTEGLFLNAANKISKSYPMIKM-
104 UniRef50_Q81G11 3-isopropylmalate dehydroge... 169 7e-41 1 18.1% 1:221 13:209 VGPEVMESAKEVLHMVERLY---GHHFHLQDEYFGGVAIDLTGQP--LPQRTLAACLASDAVLLGAVGGPRWDspEKGLLALRKGLGVFANVRPVTVESATasPLKNADEIDFVVVRELTGGIYF-----------------------SYPKERTEEVATDTLTYHRHEIERIVSYAFQLANKR-KKKVTSIDKANVLE-SSKLWRTVTEEVALRYPNVEV-
105 UniRef50_Q493R1 3-isopropylmalate dehydroge... 169 1e-40 1 17.6% 1:221 15:221 IGPETTRQVYKILNVIKKQF---QINIVTTEHKIGGDAINSEGTP--FPKSTLKYCEQSNAILFGAVGGPQWTHLKgaLLALRKHFNLFANLRPIYLADELksPLNipNGIDIIFVRELTGGIYFGQPKGRSGTGL-------------------NEYAFDTAVYHRFEIERIANIAFKLAQKR-RKRVSSIDKANVL-HTSMLWREVVSHLAKNYPDVEL-
106 UniRef50_Q1IMD5 3-isopropylmalate dehydroge... 168 2e-40 1 21.3% 1:221 14:247 IGNQVLPQAIRVLEAV-------GFEANYVHADIGWECW--CNEGNALPDRTIQLLRKHKLGLFGAITSKpgLSYFSPIVTMRQLFNLDVCMRPCLSFPGNpcGGFEEPQVDVVVFRQNTEGLYAGVEWTNPPENVRTALASHKKFAAFANT-PGEELAVSVRIITKKNAQRICEAAFKHAKKYRYKNVTICEKPNVLRETSGMMEEVAKQVQKQYPEIAL-
107 UniRef50_C1XGT6 Homoisocitrate dehydrogenas... 167 3e-40 1 19.1% 1:220 15:201 IGHEVIPAARLVLEA-------TGLKFEFVEAQAGWETFERIGTS--VPEATLEAVTHTDATLFGAATSpkVPGFFGAIRYMRRKLDLFANVRPAKHHP----VPGSRPGVDLIVVRENTEGLYVEQERSYLEG----------------------EIAIADTVITRKASARIGEYAARLAASRPRKQLHVAHKANVLPMTQGLFMNTVLAEAARFPEVK--
108 UniRef50_D2RML7 Isocitrate/isopropylmalate ... 164 2e-39 1 26.7% 1:221 57:249 IGPCIMEQALRVAKYLLKDEMASG-KVEFRTIP-GMTIEERVQKNESLPAEVLEACKACDVLVKGPFVTppWPNMVSANSLLRRALQLYAAVRPVRIPE---------KGIDWTFFRENIEGEYI---------------------WGNKGIQVDDDLAVDFKVLTRPGAERICRAAFEFAKNNGKTNVTVVTKANIVKLVDGNFLKTAHALEKEYPGITV-
109 UniRef50_D1B742 3-isopropylmalate dehydroge... 164 2e-39 1 23.5% 1:221 14:231 IGPEVTAQAVKVMEAAGSLF---GFSLELTHYPYGAEHYLST--RQVLPDHALEEMEGLDALLLGAIGDppGILERGILLKLRFHFDQYANIRPVRSF--TPGPL---GSVNAVVIRENTEDLYVGIGSTGDGAVNLPLegYVMKGQLSAFTTPPKRFAMQVAWHTLDGAARACQYAFDLALDLGAEEVTLATKSNAVRDLYGIFENACHQVASQYESVSL-
110 UniRef50_A6G3V7 Probable 3-isopropylmalate ... 164 3e-39 1 20.5% 6:220 1:218 -----MREGLKVLHAVSEPL---GIEWAIEDVPCGGQYYLEQGDLDW-PSDAPQKCDAADLILLGAVGWPDPAGtfSPVIGNRMRLNLYANVRPIKLYPGVQHRIheAGKVDMVIIRENTEGLYAPTGGKLAPGGKA-------------------DVAIDTRVITRRACEQVIRHAFELCKRRNKgrVTAIIKDNVL-HGCQLFRDVFFEIGAEYPEIE--
111 UniRef50_P04173 3-isopropylmalate dehydroge... 164 3e-39 1 17.2% 1:221 15:219 VGQEITAEAIKVLKAISDV--RSNVKFDFENHLIGGAAIDATGVP--LPDEALEASKKADAVLLGAVGGPKWgrPEQGLLKIRKELQLYANLRPCNflDLSPIKPQFAKGTDFVVVRELVGGIYFGKRKEDD----------------------GDGVAWDSEQYTVPEVQRITRMAAFMALQHEPppIWSLDKANVL-ASSRLWRKTVEETIkeFPTLKV-
112 UniRef50_C7MQT6 Isocitrate/isopropylmalate ... 164 3e-39 1 27.1% 1:221 14:219 IGPEIVEATVRVLDALAE-LHPESRGWEYVEIDAGADTYRRTGVACA-EADVRRLRDEVDATLKGPVgtPDGVEAGVLGGILRTGLDTYANIRPVRSWPGVPSRV-RADRVDYVIVRENTEGLYASRGKGVGN----------------------RWAVTDTLLTTREGTLRVARKAFTLAAGrgVRRVTCVDKSNVLR-SHAFFREVVTEVAAEFPEVEL-
113 UniRef50_B8NJA6 3-isopropymalate dehydrogen... 163 3e-39 1 26.5% 1:219 11:208 IGPEITAATIRVIEA-------TGIQPEWDFIPIADEAVRLYGH--ALPPQVIQRIKDVKFCIKAPLLAEkvVTYPSINNAIRRELNLFVNPRPIRGYVGIS---GRHEKMDMVIMREITEDTYIGWEKPLEDGAA----------------------AEAIKRVTRSASWKVSQYAFEYARKHGRKKVSCLHKANVLHETDGLFLRTFQEVARLYPDI---
114 UniRef50_UPI00016C59BF Isocitrate dehydrogenase (N... 163 4e-39 1 24.9% 15:219 19:205 --------------SVRRLFAAAKVPVEFEVHLAGRMALE-HGK-DALPKATFDAIRECGLALKTKLLQPKGVgpTNYNVAFRRQLGLFASMRPVHNLPGIPSRFT---GVDFLLFREITEDLYTASEHEIVPGVVQSF-----------------------KIVTEAACLRFFKLAFDTARKRGRKTVHCIHKANILKMADGLFLECFYRVAKEYPEI---
115 UniRef50_O59930 3-isopropylmalate dehydroge... 162 7e-39 1 18.1% 1:221 16:223 IGPEVVAEATRVLEVVS--ASSSDVEIKLETHDFGGCSIDKHGEP--LTAATLEACKLADAILLGAIGGPKWgrPEQALLALRKALGLYANIRPANflAYSPLKPSVARGVDIIVIRELIGGAYFGERKELG-------------------ARAQEDAAWDTMIYSVPEVQRITRSRRQVASPDPPLPVHSIDKANVL-ASSRLWRKVATeiQNEFPQLKL-
116 UniRef50_Q2J3B4 3-isopropylmalate dehydroge... 162 8e-39 1 19.9% 1:221 14:220 IGTEVMAEVSRLIDWLNKAGIAS---FETEHGLVGGAAYDA--DKVAITDATMALAQASDAVIFGAVGGPKWdrPEAGLLRLRKDLALFANLRPAVCYPAlsLKPEVVEGLDIMIVRELTGGVYFG------------------EPKTITDLGNGQKRAIDTQVYDTYEIERIGRVAFDLARKR-RNKVTSMEKRNVMK-TGVLWNEVITQvaREYKDVQL-
117 UniRef50_P40495 Homoisocitrate dehydrogenas... 161 2e-38 1 24.5% 1:220 34:236 IGKEVIPAGKQVLENLNSK---HGLSFNFIDLYAGFQTFQETGK--ALPDETVKVLKecQGALFGAVQSpkVEGYSSPIVALRREMGLFANVRPVKSVEG-----EKGKPIDMVIVRENTEDLYIKIEKTYID------------------KATGTRVADATKRISEIATRRIATIALDIALKrgQATLTVTHKSNVLSQSDGLFREICKEVYekYGQIK--
118 UniRef50_A8TPC9 3-isopropylmalate dehydroge... 160 4e-38 1 22.2% 1:221 23:229 IGPEVSAATVRVL----TQALGTSFPIEFRDYDAGAECFRRTG--TAFPEATQVACRQAHAVLHGAAGLPDvdGTEAGqmKIRAALDLYANVRPIRLMEGAPRRlkGPDDIRFTIVRENTEGLYAARGG---------------------GNIIRGQIATDTLVMTREGVERIVRYAAELAraDGVRRVTIVDKANVLR-SYAFFREIADGVLADCPGIEV-
119 UniRef50_Q7UTP0 3-isopropylmalate dehydroge... 159 5e-38 1 18.6% 1:220 15:215 IGPEVCDQSVRLLEIMQ--PHLDGVEFQLDRHSVGVGEYQRSGE--ALPQSAYDACLASDAVLLGAMGLppNGKEIAPQLDLRERLQLYGGVRPIRLYHEADTPLKgpGEIDFVLVRESTEGLFYGRD---------------------AIADLEADEATNLLRITRSASERVCRLAFETARRrgKKTVTLIDKANVL-SSMVYFRHVFDEVAKEFLDIK--
120 UniRef50_A0D2B8 Chromosome undetermined sca... 159 8e-38 1 20.0% 1:220 43:217 IGPEITNSVKTVFEAL--------------HVPIKFDVLDNFNFEN---DDSKSQLRKNECILLG-VMTEKNQKYTD-NYKFYKYLDLYSNITFAFSVEGIT---QRHNNTDIVVIRENTEGEYSGVEHEVYPGVVE-----------------------SIKVTTKQASLRIAEYAFEFAHLSGRRKVTAVHKANIMKLVDGLFLQACREVAQRYSFIK--
121 UniRef50_Q48806 Protein dlpA n=5 Tax=Legion... 158 1e-37 1 22.3% 1:220 17:232 IGIEVTEATLPVFEVL-------DVPVILNYGDIGWEFWKKEG--AAIPSRTWQLIASSDTVLLGAITSKpnPYYVSPVIQLRQGLDLFANVRPCFSIDDQSKPF------NFCIIRENSEGLYCGFDYFPLP----KAIHSLLAESQHWQTIPADEASCALRLQSKSGLTRLFDFAFKHAMQTGMPRVTLADKPNVLRESGEFTRKIFESTAQRYPKIQ--
122 UniRef50_A9A2N6 Isocitrate dehydrogenase (N... 158 2e-37 1 25.8% 1:221 13:201 IGPEVVDSMLRVLK-------ECNFQSELILCEAGSEQWDKNgdASYIPDVTMKILEETDCCFKGPTTtpVPGAPRSVAVTLRQKFDLYANIRPTKTYDRLTP----DRKLDCVCFREATEGLYTGVE-----------------------AKITDDAAIAIRKITRQGSRRLIDSAVDWANKFNMKKMVAVTKRNILKQTDGIFWDETQK-AVEGTDIEL-
123 UniRef50_B1L5I7 Isocitrate dehydrogenase (N... 157 2e-37 1 25.5% 1:216 11:188 VGPEIMGATLSLLE--------RYIGADFIEIKAGKSYFIEEGKP--IEDNAIEKIRECDSLLKGPVATpkGPSYPSVNTLLRREFKLYANVRPFRSYEGISI-----RRIDTILVRENLECLYYGWEVE------------------------DEDRAIAMRVITKRGAERISEFAFNLAKREGRGRVTAIHKRNILKRTDGLFLDAFYRVASKF------
124 UniRef50_B1L3C1 3-isopropylmalate dehydroge... 157 3e-37 1 20.8% 1:216 12:189 VGPEIIDAVIPVLETLSDLM---NLPLDLRFFEAGDETKRKRG--VALPEETLNGVMNSDATLMVAIG----ESAREVILPLRQKLDLYVNLRPAKSYP----VPRAIPGFDLTIVRENTEDLYVMSGWR------------------------GLDTAVDLRIITRRASERICRFGYRYARERGKSRVYVVHKANVL-GGCMLFREVCSRVAEEE------
125 UniRef50_Q2YL58 3-isopropylmalate dehydroge... 157 3e-37 1 17.2% 1:221 14:220 IGPEAMAEVRKVIAFLNSDL---NLGFETEEGLVGGCAYDAHGQ--AISDADMEKALAADSVLFGAVGGPKWDspEAGLLRLRKDMQLYANLRPAICYPALAHSSSLkeGLDILILRELTGGVYFGEPKEIID------------------LGNGQKRGIDTQVYDTYEIERIADVAFELARTR-RNKVTSMEKRNVMK-SGVLWNQGVTARHKehADVQL-
126 UniRef50_Q12545 3-isopropylmalate dehydroge... 156 6e-37 1 17.2% 1:221 15:223 IGPEIMAEAIKVLTTIE--THRPNLHFNLTTDLVGGTSIDTHGVP--ITQSVLDAAKASDAVLFGSIGGPEWAgpESGLLQLRQHLDAFANLRPcfLVPSLvsPIREhkGTRFIVVRENCGGAYFGEKKEE------------------------EDVASDLWVYTRPEIERLARVSAAVARIMGRstVWSADKANVL-ASGRLWRRITSDiaKEFPDITL-
127 UniRef50_Q2K2V0 3-isopropylmalate dehydroge... 156 6e-37 1 16.7% 1:221 14:220 IGPEAMGEVRKIIAYMNEAMDAG---FVTDEGLVGGCAYDAHG--AAISEADMQKALAADAVLFGAVGGPKWDspEAGLLRLRKDLQLFANLRPAICYPALAskPELVEGLDILIIRELTGGVYFGEPKEIID------------------LGNGQKRGIDTQVYDTYEIERIAGVAFEMARTRQ-NRVCSMEKRNVMK-SGVLWNQVVTETHkkYSDVQL-
128 UniRef50_C7RJH9 3-isopropylmalate dehydroge... 155 1e-36 1 18.7% 1:219 17:220 IGPEIVASSLHVLEVLNERM--GGIGFDFWHLEGGAAHYQKTG--TAFSDENMAACKKADAVLLGAIGLPhdGTEVTTQLDLRVEMDLYAGLRPIRSYPSLPRVlkRASQIDLVLVREQTEGiyS----------------------RCRGTIEDDRVAWETMMISRNGTSRVSEFAFRVAERRAkgKVLCVDRSNALT-SMAFFRRIFGEVAERHPSV---
129 UniRef50_D2VM48 Isocitrate dehydrogenase n=... 153 4e-36 1 24.1% 1:220 48:276 IGVEICSCVCELFHYA-------NIPIQWDTYLVSGSFFGVGSDSSLNppDLHQSILNNKVVLKGPFIT--RDVSKSIDRMLALKYGLYAHVVPVKAPQNLPPSVFTprDVDMVVVRENTEAEYSGLEHQVQPGVVE-----------------------SLKIITRDGSMRIAKWAFEYAKQSKRSKVIAIHKANIMKKSDGLFIECCKQVAKEYPDIQ--
130 UniRef50_B5RJP2 FI08066p (Fragment) n=18 Ta... 153 5e-36 1 21.2% 1:222 97:274 VGRELMDAVQEVICAVKA-------PIEWDVHD-----EFKAKDSDDVSPEVLKSLRANKVGIKGPVDS------RHWQRQIRKQFAQFAYVSLCSHIEGLDSPY---GDFDVVIIRDQMEGDYSGIEHLVVPGVMQT-----------------------IKVSTTAGAARIAEFVFNYAVKNKRKRITVAHKANIMRMTDGNFLEAMRAEADKHVDDVLF
131 UniRef50_Q4FP17 3-isopropylmalate dehydroge... 152 9e-36 1 20.8% 1:221 17:223 IGPEVIQEVKKVI---LWLNSNKSLDFEIDEDLAGGCSYDKHGTP--ITDEVFYKALESEFVMLGAVGGPKWDNLEFSKKPErkELKLFANLRPAICFEQLvlKPEIVSGLDIMIVRELTGGIYFG------------------EPRGIKPIENGERKGINTHSYTTSEIVRVAKVAFDLARKRS-NRVTSCEKSNVMEAGQ-LWKEEVQELhkEYKDVEL-
132 UniRef50_Q0X0C1 Putative dehydrogenase n=2 ... 151 2e-35 1 24.7% 1:219 30:222 IGPEVIEPALDVLDALGLGTRTDILD------HVNADTYLRTGE--ALTGSDLDRIRSSEAALLGAVGDPRLGdvRGVLTTLRLELDLYVNYRPARLWHDRLSPLRDprAIDCVIVRENTEGLYSGIG-------------------GGARTGTPEEIAVDVDLSTRHGVSRVLEFAFSAA----RRSVCLVDKANAVRNGGQLWQRCWGEAVARHPHI---
133 UniRef50_P34738 3-isopropylmalate dehydroge... 150 2e-35 1 19.5% 2:221 15:220 -GPEVVLEAIKVLKAIETNSPSAG-KFNLQNHLLGGASIDKHNDP--LTDEALNAAKAADAVLLGAIGGPEWgrPEQGLLKLRKELGTYGNLRPCNfvDSSPLKAEVCRGTDFIVVRELTGGIYFGDRTEDDGSG----------------------YACDTEPYSRAEIVRIARLAGFLAlkNPPAKVWSLDKANVL-ATSRLWRKTVTDvsKEFPQLQL-
134 UniRef50_C0W9Q2 Isocitrate dehydrogenase n=... 150 4e-35 1 26.2% 1:221 48:240 IGPYIMKAALLVARKLLKKEIADQR-VEFVPIK-GMTIEERARQNKSLPPAVLEACKACDILVKGPFVTPrwPNLLSANSLLRRQLQLYAAVRPIRIPE---------KGIDWTFFRENIEGEYI---------------------WGNKGICVGDDLAIDFKILSKPGAERLFRNAFEYAKSSGKTNITVATKANIVKLVDGNFLKVAHAMEKEYPGIHV-
135 UniRef50_Q9LQK9 Putative isocitrate dehydro... 148 1e-34 1 22.7% 5:220 12:183 ----VTNAVHQVMDAMQA-------PVYFETYIIKGK------NMNHLTWEVVDSIRKNKVCLNGRVNNSLCGGA-------RKELDLFASLVDCFNLNGQPS---RHENVDIVVIRENTEGEYAGREHEVVPGVIESFQVT----------------------MTKFWSDRIAKYAFEYAHFSKRKKVTAVHNNGKykLADAFFLESCQEVAKMYPNIT--
136 UniRef50_A1SWV5 3-isopropylmalate dehydroge... 148 1e-34 1 17.6% 1:221 14:223 IGPEVMKEAVKVLKLIEQR--NEDVNFELNDVLFGAAAYFAMGH--AFPDETKAACDKADAILKGTIGLNHEDseRGALLPLRRRYNTFANFRPVYLPKGLasPLKagEGIDIMIIRELVGGLYFGEKEMGVNADGKRFVREVLE-------------------YDEDQIRQIVKVGFEVSMKR-KKVMHNIHKSNVLK-SSVLWNEIVEEESKNYPEVEV-
137 UniRef50_Q2RV53 3-isopropylmalate dehydroge... 148 1e-34 1 16.7% 1:221 15:221 IGPEVMAQVRRVMDWLNQTGRTA---FEVEDALVGGAAYDAQGTP--LHDDTVALALAADAVLLGAVGGPKWdkPERGLLRLRKDLELFANLRPAMVFDALalKTELVSGLDVMIVRELTGGVYFG------------------QPRGISALPNGERRGVNTQVYDTHEIVRVAKVAFDLAGKRG-KRLCSVEKANVME-SGLLWREEVTKLGADYPEIAL-
138 UniRef50_Q5JFV8 Homoisocitrate dehydrogenas... 148 1e-34 1 25.8% 1:221 12:188 IGPEVIDGAVRVLKAVTGR-------VRFEYYEGGVDVFQECGSP--IREEDLEEIRRSDAVLFGATTTPFdpGYRSLILTLRKELGLYANLR---IIPDLRT------GREIVIVRENSEGLYFGIGAVVNG------------------------RAVDVRLITREGAERIARFAVEQAKARG-SFITFVHKANVLT-GDKFFRRIVREVAGEE-GVEV-
139 UniRef50_Q1ARE1 3-isopropylmalate dehydroge... 147 3e-34 1 20.8% 1:221 15:212 IGPEVVAAARR---VADAAAARFGLTLEYEERRIGAAAIREEGAP--VSKETLRRAGEADAVLLGAVGDPEFDgpEAGLLALRRELGTFANLRPVAAIPAlpLRPGVAEGVDLLIVRELTGGAYFG------------------------EKEEGEERASDLSVYTRGEVERVARVAFEAARGR-RGRVASVDKANVL-ATSRLWRRVVGEVARDYPDVAL-
140 UniRef50_Q18GT1 3-isopropylmalate dehydroge... 146 5e-34 1 23.4% 1:214 17:192 IGQEVIPAAVAVLQAVDE------VGFSFTEKQAGDDTRDQTG--AALPETTYEAAADADATLFGA----AGETAADVILPLREAVGSFVNIRPARAYPGVDALQPE---TDLVFLRENTEGVYSGHE-----------------------DRLSEDLSTLTRVITTSASEQLAEYACSYVTERSIDGFHTVHKANVMQETDGRFRDAVSRVAA--------
141 UniRef50_C9SEZ4 Homoisocitrate dehydrogenas... 144 2e-33 1 25.8% 1:198 16:197 IGKEVIPAGRRILEAL---PSYLGLKFEFTDLHAGFETFERTG--AALPDKTVEILreCDGALFGAVSSppVKGYSSPIVALRKKLDLYANVRPVKTV------LSAAKPIDMVIVRENTEDLYVKEETTRDTP--------------------DGKVAEAIKRISERASHRIATMAGDIALRRQkpLVTITHKSNVL------------------------
142 UniRef50_B4MP27 GK19462 n=1 Tax=Drosophila ... 144 2e-33 1 19.9% 12:222 1:176 -----------MIESLVKVFSTVQVPIDWDVFH---EHKINSAEGEDVSPKLLESLCRNKIGIKGPFESGPC------LRKLRKKFQLFAFVAVCRNLEGQNTRY---GKLDCLIIRDQVEGEYSGIEHRVVPGVMQT-----------------------IKVSTAEGADRMARYVFEYAKKNNRKKITVAHKANIMRLTDGTFLSPMRREAAKYQDDIMF
143 UniRef50_Q961P4 GH13226p n=4 Tax=Drosophila... 144 3e-33 1 21.9% 13:222 1:173 ------------MDAVQEVICAVKAPIEWDVHD-----EFKAKDSDDVSPEVLKSLRANKVGIKGPVDS------RHWQRQIRKQFAQFAYVSLCSHIEGLDSPY---GDFDVVIIRDQMEGDYSGIEHLVVPGVMQT-----------------------IKVSTTAGAARIAEFVFNYAVKNKRKRITVAHKANIMRMTDGNFLEAMRAEADKHVDDVLF
144 UniRef50_A1WV93 3-isopropylmalate dehydroge... 144 3e-33 1 20.1% 1:219 18:242 IGPEVMAATRHALEAL------PGPALVLTELGWPAHAWHR-DHGEMMPADWRGQLAGYDALLLGALGDppDGVSLAPLLQLRKGLDLWACERPAVPLAGAPMPLSDPRAldLLVIRENSEGEYVDQGGRLAAG-------------------TPRETATQLEVFTRAGTERIIRHAFERalRAPraAVCVVTKRNAVQYAGELWSEVFAEVAAEYPGI---
145 UniRef50_Q2VZV2 3-isopropylmalate dehydroge... 143 4e-33 1 17.6% 1:221 14:220 IGVEVMAQVRRIIDWMGRKR---KIEFEITEGLLGGAAYDVHGTpaETLEAALAADAVLLGAVGGPkdLPFDKKPERGLLGIRKDMGLFANLRPATVLEALalKAEVVSGLDIMILRELTGGLYFG------------------QPRGIDTLPDGTRKGYNTLVYTTPEIQRIGRVAFDLARKRN-KKLCSVDKANVLECT-VLWREEMIKLQkeFPDVEL-
146 UniRef50_A4FEJ6 3-isopropylmalate dehydroge... 142 6e-33 1 22.3% 1:220 17:218 IGPELVRSAVEVLRAAAGR----DVELRFTSEDAGADAFRRTG--SAMSAATLERIrrYHGVLKGPVghPDGTEAGLLGGVLRGGLDTYANVRPIALLPGVDAPLRG-TAVDYVIVRENTEGLYLSRGRGVGN----------------------DRACADQLLMTRHGVERVVVHAFELATRrgVRRVTCVDKSNVLR-SFAFFREVFDEVATRYPQVE--
147 UniRef50_UPI000185C11E 3-isopropylmalate dehydroge... 142 6e-33 1 21.3% 1:221 25:256 IGPEITDACRGLI-------ADVFPHWELTETQIGWSQWRAHGNP--VPQETWETLGRSDAALLAAITSKpgLNYRSPVLQLRQRLDLFANIRPV-TLPGAAA--------DFTIVRENTEGLYspHDAPADSPHHHLWAEVVEDSTVARAVDKRGEVAVSLRVTTSFAWHRLARQAAKLALARQapTVTVADKPNILRDSARVIRGAVEEVAEEYPQVAF-
148 UniRef50_Q05FQ8 3-isopropylmalate dehydroge... 142 9e-33 1 16.3% 1:221 12:204 IGPEIIKQVIKIVKS----CIYTGYKINIIYNYIGGISIDKFNTP--ITNNLISIIKYIDTIFLGCVGGYKWNhpEYGLLKLRKKFNFFTNIRPIK------CPFK---NIDIIIVRELNGGIYYGK---------------PKGFSKQIINQIPTWYAYNTKIYNEQEIIRLARISFNLALNR-KKKLCSIDKSNVLE-TFKLWKKTINYVHKFYNKVKL-
149 UniRef50_B8M3W0 3-isopropylmalate dehydroge... 140 3e-32 1 17.2% 1:221 15:220 IGPEIIAEALKILAVLEEEL--PNFKVQISYGLIGGASLDKTG--SAITDEVLETAVASDAVLLGSVGGPEWasPEKGILHLRQRLDAFANIRPCRFYAssPLKPEIAAGVDFVLVRENCGGAYFGTKTEFEDEA-------------------------------RTEVERCARVSAALARTFGRGkvWNADKANVL-ASGRFWRTVTHDIFeeFPDIEL-
150 UniRef50_Q2HAA2 Putative uncharacterized pr... 139 6e-32 1 18.6% 2:221 15:220 -GPEVVAEAVKVLRAIETHSPSVG-KFNLQEHLLGGASIKVHNDPLTAKALAAAKAADAILL--GAIGGPEWgrPEEGLLRLRKELGTYGNLRPCNfvDSSPLKADVCRGTDFIVVRELTGGIYFGARTEDDGSG----------------------FAMDTDAYSRAEIERIARLAGFLAltSPPSKVWSLDKANVL-ATSRLWRKVVTEvaNEFPQLEV-
151 UniRef50_Q7XZ87 Isocitrate dehydrogenase (F... 139 7e-32 1 27.9% 1:154 42:183 VGPEISVAVQNIFNAA-------DVPIVWDEHHI--DVDNAKPGQDLISADALDSLRRNRFGLKGPMATPIGKGYRSLNLTLRKALGLYANVRPCVSIPGVQTPY---DDVDVVTVRENTEGEYSGLEHVVYPGVVESLKVITPERVNARVQVP--------------------------------------------------------------------
152 UniRef50_B2J8P1 3-isopropylmalate dehydroge... 137 2e-31 1 17.6% 1:221 19:208 IGPEVVEASLKILQHVAKI---QGFTLQVDYGWLGATAFEQLG--SYFPQATTELCDGADGIVFGAVSQ-------GGLLELRKHFDFFCNLRPIRSVNSlsLRPEKIQGLDILIVRELVSGIYFGPSGRSSDE--------------------RGNYGYHTMRYYDEEIRRIARKALEQAQYR-RGLLTVAHKENALPHLH--WTRLVQEEATKFPNVIV-
153 UniRef50_A0P1S6 3-isopropylmalate dehydroge... 137 4e-31 1 19.5% 1:221 11:218 IGVDVAEAAIAVLETALKHTGEPAPR--YDEIQAGAGYFKETG--LDIEDGGEERAGLADAIFLGAIGLpaNGTEISPHLRLRDRFGLYAGVRPVKAYPNAPQRLADPrgIDLVILRESTEGlySAAAHK-------------------RSLVVNDDEVQDVLRITRKTTTKLHRFAFNLARKRrpGRLTCVDKANVFT-SLAFFRQIFDEVKSEFADVPV-
154 UniRef50_UPI00017936A6 PREDICTED: similar to isoci... 133 4e-30 1 16.9% 2:220 52:236 -GPVVLAAVRKIFKAAL-------VPVEWDYQTLSVYRDHKTNRMTVNPQ-LLDSAIETGLVLCAKDSSPrnDSLESDSLALHKALNAFVGVRKFNSVVG----HEPYGPINLVNIREHVSGEYSEIEHLVSPGVVQ-----------------------SIKTVSKKISVEVAKLAFDYACKHGHSRITVLHKADVMRLSDGIFLKACREVSACYPDVE--
155 UniRef50_UPI00003C8595 isocitrate dehydrogenase n=... 132 8e-30 1 24.7% 1:219 34:237 IGPEITGAMIGVVNSAIELAYQGSRSIEWHKILIGTEAYEKFG--TYVPEDSIKEIQKMYIAMKSTLN--FMPDKRDLNTILRKRLGLYSNIRILKYIEGMDIPVNTFNRLNLTIIRDSTPNSHI---FYHSSESTDDLIRFISDNYGL---NITPDSGIYMMPQSKFRTRKIAKQAVRYSRRNGKKKITILESQQNHE-----FANWCIEEASAQEDV---
156 UniRef50_UPI00017440F3 Isocitrate dehydrogenase (N... 130 3e-29 1 24.6% 1:195 12:173 IGYEISESLVKIFDAAK-------VPVEFETENAGSDVYEKTGE--LIPESLYESVERNKIAIKGPITTPIGKGFRSINVYLRKKYDLYTNFRSSRNLPGIETRY---DNIDLAIFRENTEGIYIGEEKYENEEKT---------------------SAIAVKRITKKGSEELLKVLLNMQRIMEFRKLQLFIKQ---------------------------
157 UniRef50_Q4P2R4 3-isopropylmalate dehydroge... 127 3e-28 1 16.5% 1:218 23:208 IGPEVMAEVLPLFDVIQSHF---GIKVETFERLIGGSCLDQHDCP--IQESTLQEASECHAVLLGSVGGPKWdrPETGILRMRKHLNLYANVRPAKIISERqsSLKEhrGVNIITLRENAGGIYFGRKQEPDPLAH--------------------------------------KAALSLASSHGPLPIISVDKANVM-ATSRLWRQVVTeiRDEFPQ----
158 UniRef50_P48735 Isocitrate dehydrogenase [N... 126 5e-28 1 18.1% 7:221 56:278 ------DEMTRIiqFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTI--DSALATQKYSVAVKCATITPDEARVesPNGTIRNILGGTVFREpcKNIPRLVPGWTKP----ITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGmnTDESISGFAHSCFQYAIQKKWP-LYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDF-
159 UniRef50_C5GTE7 Tartrate dehydrogenase n=2 ... 125 1e-27 1 17.6% 1:221 26:200 IGPEVIEAGNY--QSAEETNRVAWILLNWPSRTLSGAVR--------ITRNTADISPISSSTFLW----------FSSYLPLRSS---TSNM-PTRVFHGIQSPLH----LDWVIVRENSEGEYAGHGGRSYAGK-------------------PWEVATDISIFTRHGVERIMKFAFEAARSRAKKHITVATKSNAQRNGLVVWDEiaAEVAAQFPDVTC-
160 UniRef50_O75874 Isocitrate dehydrogenase [N... 124 2e-27 1 14.0% 7:221 16:239 ------DEMTRIieLIKEKLIFPYVELDLHSYDLGIENRDATNDQ--VTKDAAEAIKKHNVGVKCATITPDEKRVesPNGTIRNILGGTVFriICKNIPRLVSGWVKP----IIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGttYLVHNFEEGGGVAMGMYNQDKseDFAHSSFQMALSKGWP-LYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQF-
161 UniRef50_C5EHC0 3-isopropylmalate dehydroge... 123 4e-27 1 16.7% 1:221 24:228 VGPEITREAVLTLKRAGEVY---GRSFQFTEAIAGTAALDR--GQCPLPRESLKTCLEADSILMGKLAVGRHPgpESILGLLRTGLCLRSDIRPCFFAEALrcPLkrKKGMDILIIRDIAGGMFTTEGKSSNLCNV--------------------RAAWDTESYDETLIRDSARLAFQLAASRKRK-VTSLDKA-ILLSSSVLWRQILEETHRDYPEIEL-
162 UniRef50_UPI000038E0FC 3-isopropylmalate dehydroge... 122 1e-26 1 17.3% 1:214 12:210 IGKEIIPQVCDLVTSI-------DPSVNFTFYNISSERYINKG--ITIKDSEIDELKSYNSIFFGAIGdkPGIMEQGVILRLRKELDLYMNIRPAISFSRITG-----NNIHMTILRENKEDFYSDISGSLNEHKLFRQKGNFYNYNIDINSESDDTIYYTMGFLSRKNLKRFFNMAYKIA---DTETVTITDKANAVDMYS-LWREIAIEESE--------
163 UniRef50_B6KL81 Isocitrate dehydrogenase, p... 121 2e-26 1 17.7% 7:221 194:416 ------DEMARVIWaiKEKLILPYLDIPLMYYDLSIQHRDKTDDQVTI--DAALAIKRHGVGVKCATITPDEQRVksPNATIRNTLDGTIFRAPikNVPRLVPSWTKP----IIIGRHAHADQYKALDFTVDKPGRFVMSFIPADKSNPEVHEVYEFKGGGVAlnTDASIKGFAHSCFQYALDQKMP-LYLSTKNTVLKKYDGRFKDIFQTIYEKEYKQKF-
164 UniRef50_B8FQF2 Isocitrate/isopropylmalate ... 119 7e-26 1 15.4% 1:221 14:222 VGKDVIPLGAKAMQKAQEIL--GGFELDCRYYEAGVEYAVKTGKMCE--DNLGEDIAKADAMLCGSAGHYDADMSKsvLQFLRSGMGNSIGLRPLRLRKGIDCPLRNREEIDVLLVRQLAEGFYIRPGH-----------------------MIGEDAAYDTIVVTRNVTEKFADTCFRLARGrgKKMVTLGNKHGNVTCFD-FYRKIFTEVSAGYPDIGL-
165 UniRef50_B1VH60 Putative dehydrogenase n=1 ... 119 8e-26 1 21.7% 1:221 17:214 IGPEIVAPTVQAVELALQ--ASGEATPEFVPLLLGREAINATGR--IVPEETWETITGLDGWILGPHDnpSVAGQLNPSAHLRKQADLWANIRPVRGVPGAVHP-----DLDVVIVRENTEGMYADRNMLMGSGDITVNGEVSLAIGVFTQTKIRRIVRRAAAI-----------------AAARDGVLTVAHKSNVLTETSGRYVAEAKACAEEF-GVEV-
166 UniRef50_Q6L0K7 3-isopropylmalate dehydroge... 119 8e-26 1 18.6% 1:215 12:201 IGREIMPGVAAAISSIS--------DINFVTFDISSERYIKTG--IIIKDDELEELKNYRAILFGAIGDppGIMEQGVILRLRRELELYMNIRPVRSFD---------DKIKITILRENTQDFYTDISGIIPGKRSFNVNGTRIEIDGSSC----DEVYYTMGMLSYRYLKKFFNKAFSIC----DSTVTVTDKANAVKMYN-LWRSTAMEAAIE-------
167 UniRef50_B9SFA3 NADP-specific isocitrate de... 118 1e-25 1 17.2% 7:215 93:309 ------DEMTRVirMIKDKLIFPYLDLDIKYFDLGILNRDATDDKVTV--ESAEATLKYNVAVKCATITPDETRvrSPNGTIRNILNGTVFREpcLNIPRIVPGWKKP----ICIGRHAFGDQYRATDTLIKGPGKLKMIFVPEDGNTPLELDVYdgPGVALAMYNVDQSIrfAESSMSLAFAKKWP-LYLSTKNTILKKYDGRFKDIFQEVYEE-------
168 UniRef50_C7YX79 Putative uncharacterized pr... 117 3e-25 1 18.2% 2:221 21:222 -GPYLASYVERTLDLIQRVRRNVSFKVSRHDF---GGVALAAGAGTALPSTTLGACRQSDAVLVCGCGDPrgIEPERGLLTLRQELEGCVNIRPVR-FPSSQlkPEVVEQLDITFFRDLTSGVYYGRRKEAG----------------------DDGEAYDTTPYSRQTIERIARLAGTYAMqsPPKPVHSIDKHNVM-ATSRLWRSVVAHVFeeFPQVPL-
169 UniRef50_P50217 Isocitrate dehydrogenase [N... 116 5e-25 1 17.3% 7:214 18:234 ------DEMTRVikSIKDKLILPFLELDIKYFSLGLPHRDATDDKVTV--ESAEATQKYNVAIKCATITPDEARvrSPNGTIRNILNGTVFREpcKNIPRLVPGWTKP----ICIGRHAFGDQYRATDTVIKGAGKLKLVFVPeeKTEFEVYNFTGAGGVALSMYNTDESVrfAEASMNMAFQKKWP-LYLSTKNTILKKYDGRFKDIFQEVYE--------
170 UniRef50_UPI0001C31665 isocitrate/isopropylmalate ... 112 1e-23 1 16.1% 2:219 16:206 -GQELLDQAVRVLD-----PEVTGLPLELERFDLSLENRRATQNGVV--SDAAAAMRTCGFGIKAATITPEgdDVGSPNRILREEVDGKVIVRTGRRIPGVTPIAGVHYPIS--IVRMAIEDAYGAKQWREGDAGAA------------------DEVAYRTEHVTRSTCRAVSEYAFRTARAMQ-ARVYGGPKWTVSPVYEGMLKEEMDAAAARHPDV---
171 UniRef50_A6GJ83 Isocitrate dehydrogenase n=... 112 1e-23 1 18.6% 1:221 19:200 IARELSQAVHTVADALP-------FEIEFIPVDLSDESREAKGD--AIYDEAEAAMRRYGTSLKYPTAT----TKESPNRVLRERCNFAVIHRPVATIPGIQTHYN--ERIHLDIVRIATGGTYEDAGRRIN-----------------------RDTAVSIRAIERRPSVLASRFAFRLAQLRD-SNVIATSKYTIQKATDGLFQEAARGVARDYPATEF-
172 UniRef50_Q0A635 Isocitrate/isopropylmalate ... 111 2e-23 1 19.0% 1:221 38:234 VGPEVIDVALSLLRLLGE---ATGQRFEVRTgpIGRQAERLTGRG--LTPEVRDFCAQV-FAQGGAVLCGPGGG--RFVYDLRRHFDLYCKLIPLRHWPAlvLRPEAARSADVLIVRENASGLYCG-EWGSEGEGAA-------------------RSAYQVCRYRADEVERILRTALRLAGQR-RGDLVVVTKPGGVPAISALWHDALTAVAGEHGAVRC-
173 UniRef50_Q0CXI1 Isocitrate dehydrogenase, m... 109 6e-23 1 15.7% 31:221 97:294 ------------------------------HRPQGIEYRDQTDDKVTV--EAAEAIKKYGVGVKCATITPDEARVesPNGTIRNILGGTVFREPipAIPRLVPGWTKP----IIIGRHAFGDQYRATDRVIPGPGKLELVYTPANGQPESVQVYDFQSGGGVAmnTDDSIRGFAHSSFKMALLKGLP-LYMSTKNTILKRYDGRFKDIFQEIYEAEYKKEF-
174 UniRef50_Q8N9Z6 cDNA FLJ36019 fis, clone TE... 107 4e-22 1 19.4% 81:209 1:103 --------------------------------------------------------------------------------MLHTTLDLYASVIHLKNLPNVET---WHKDVDILVVWENTEGEYSNLEHESVKGVTE-----------------------SLKIMTKAKSLRIAEYAFQLAQKMGCKKVMAVHKVNITKLGDGPFLQCC-------------
175 UniRef50_A5B8K4 Putative uncharacterized pr... 106 7e-22 1 15.6% 7:205 73:279 ------DEMARImrMIKDKLIFPYLDLDIRYFDLGILNRDATDDKVTV--ESAEATLKYNVAVKCATITPDEARvrSPNGTIRNILNGTVFREpcXNVPRIVPGWKKP----ICIGRHAFGDQYRATDTVVEGPGKLKLVFAPENGDPPVELNVYdgPGIALAMYNVDESIrfAESSMSLAFAKKWP-LYLSTKNTILKKYDGRY-----------------
176 UniRef50_B5DZV4 GA24694 n=6 Tax=Drosophila ... 105 1e-21 1 17.4% 50:221 107:251 -------------------------------------------------EEYFNSVLRNHAAV--HVDILCDKEAKKKSLKICNDLDLYVFMTRLRSFPGFKCRFP---DVDIQVIAQNNIGNYSELEYAPVKGVVE-----------------------ALRVVTHENVTKYLRHAFEAAIRAGRCRVTLIHKANEWPVTDGAMVEIAEKMHAeyCSIKL-
177 UniRef50_B7KHW3 Isocitrate/isopropylmalate ... 105 1e-21 1 15.1% 2:219 17:206 -GEELLIQALRVLQ-----PSVIRQPLQFLDYDLSLENRRATDNKVV--WEAAQAARDSGLSLKAATITPEIAgvGSPNAILREALNAKVILRTGRRIPKIRPIAGVYSP--IAIVRMAVDDAYGSKEWRETTEN-------------------GDEIAYRTSKISRSTCRAVAEFTFQYA-KRTKAKVFGGPKFTVSATYEGMFKEELDAAAKRYPEV---
178 UniRef50_D0WIJ5 Isocitrate dehydrogenase, N... 102 1e-20 1 15.2% 7:216 48:265 ------DEMTRImqMIKDELICPFVDLKTEYYDLGLAHRDETDDQVTV--DSAEATKRLGVAVKCATITPNAARVesPNGTIRAMLDGTVFRApvRGIDPCVKNWVRP----ITLARHAYGDVYRDAEMRIPGPGTVELVYTASDGTETRrhEFTEPGVVEGMHNLDASIESFARACFDFALATSQD-VWFATKDTISKTYDHRFKDIFQEIfaDY------
179 UniRef50_B3MF82 GF11274 n=1 Tax=Drosophila ... 102 1e-20 1 18.5% 49:216 97:236 ------------------------------------------------TDDFYNSVLRNRSAV--HVENVVDAEAKKKSMKLCNDLDLYMFKCRVRSFPGFNCRFP---DVNIRIIAQNNMGVYSDLEYSPVKGVVE-----------------------AISVSTQEGNEKYLRKAFATAVKANRKRVTLIHKSTEWPITDGAMVSAAKEIHKDY------
180 UniRef50_B8BX37 Predicted protein n=1 Tax=T... 101 1e-20 1 13.0% 2:217 89:310 -GEEMTHYATQLL---LNQWIEPYFDIswETFDLSCKARDDSDDATLI--DAVEAGKRIGAIFKEPTITPSAIQVqsPNGAMRRGWNGITISRDTIHIEGIELGYKNQ----VLFERHAVGGEY-GAGWNEVGEGTLLTTYIPKdpFVVDKRDLTDKHNVCVVYHnyDNVRELAHLFFKRCLEHKVTP-YIVTKKTVFKWQEGFwkRVFDDTYKDEF-----
181 UniRef50_A4SBK5 Predicted protein n=6 Tax=E... 100 5e-20 1 11.8% 2:222 18:243 -GEEMTAYVMDLIRAKWIEPRVDTTA--WREFDL--RAKNRDDTEDQVLRDVIEAGKAVKAIFKEPTVTPTADQVksPNGAMRRGWNGITISRDTIHIDGVELGYKKP----VFFERHAVGGEYagKGTLVTTFTPSEGPDAGKPVEVDSRTITDNEAAVVTYHNPYDNVHELARFFFGRCLEAKITP-YVVTKKTVFKWQEPFW-QIMKKVFDEEYKSKFV
182 UniRef50_Q567A6 Isocitrate dehydrogenase 3 ... 92 2e-17 1 17.0% 1:165 61:212 IGPELLNHVRELFR-------FSCVPVDFEVVHVNSSSTSEDDIS-----NAIMAIRRNGVALKGNIETNhpPNHKSRNNLLRTSLDLYANVMHCQSLPGVQT---RHKNIDIIIILEKSEFSALLAENEKIKVELLQLRIQLADVINKRRADIILDLNIEKSRV---------------------------------------------------------
183 UniRef50_D2SD16 Malate/L-lactate dehydrogen... 91 2e-17 1 14.9% 1:215 12:195 VGEEVLDGPTRLLRLLAERGEVE----VTGPWPVGARAAAETGD--VLPAGTLAACDAADAILLGAVGEDpcPRPEVALHRLRERYDLRISVREIPFADGR----------ELTVVRNLIGGSYGGADDRVLREDGSE--------------------AADVLRLTRERVAEVVHTACDVLGRRGGGRLVSVDKAN-LYATGRLWRQVAGDVARE-------
184 UniRef50_Q6L1Z1 Isocitrate dehydrogenase [N... 91 3e-17 1 25.6% 2:181 27:187 -GTELTRAMINAVNSAIEIAYSGSKSIEWKKIYIGREAYEKYGK--YLPRESIEDIRKTVFVMKGPLSSNING--HDININIKRILNLYTDVKCITGLPGLS------EGKEIFIFSPSIDEVY---HFSYDSEDSDMLRQYLQQSFNIS---IGGDSDIFLKGTSRY---RIIKIASKIA-----------------------------------------
185 UniRef50_A5BNI3 Putative uncharacterized pr... 88 2e-16 1 19.4% 1:103 53:156 IGPEVISVAKNVLKLAGSL---EGIEFGFQEMPVGGCALDLTGVP--LPEETLLVAKQSDAVLLGAIGGYKWDspETGLLQLRSGLKVFANLRPASVLPQSTP-----------------------------------------------------------------------------------------------------------------------
186 UniRef50_B6QRT7 3-isopropylmalate dehydroge... 86 9e-16 1 20.3% 1:133 15:147 IGPEIIAEALKPLTVLVEE--RPDFKVQVRYGLLAGASLDKTNEP--ITDKVLDAALATDAVLLGSVGEPEWanPEKGILRLRQRLDAFANIRPCR-FCASSLVEQSPLKSDMVNG-VNFGEQYAARSRSTGG-----------------------------------------------------------------------------------------
187 UniRef50_B8ARP0 Putative uncharacterized pr... 85 2e-15 1 17.4% 76:213 32:168 ---------------------------------------------------------------------------RSPNGTIRNILNGTVFREpcKNVPRILSGWKKP----ICIGRHAFGDQYRATDTIINGPGKLKMVFVPDGAEPVELNVYnkGPGVALSMYNVDESIrfAESSMAMALSKKWP-LYLSTKNTILKKYDGRFKDIFQEVY---------
188 UniRef50_Q03UU7 3-isopropylmalate dehydroge... 84 5e-15 1 15.2% 5:221 16:209 ----VIDRALGIIKS----SVNDSTAFEVTELPFGVNGVLSFNEP--LPNQTLRELKNYDGILVGALNQEVGtsVQESLVALRKYLNItaVQISDNNVDASPLKNQIVRDTDFIIV-----------------------QSAKRANDHVDGNISVDDFAQDTITYEQREVEQVITAGFERAMNRKRA-VTVVTPFDSF-YTSKIWALTAEKIAKIYPDVVV-
189 UniRef50_C7YNU4 Putative uncharacterized pr... 83 8e-15 1 9.7% 68:221 36:167 -------------------------------------------------------------------GAPATSRPERGLLKLRKEMGTYGSMRPCFF----------------------ASDSLVAPQGRGVPRHRLCHCARAHRRYLLWRAQTGSGSAWNTEPYSHAEVERFTHLAGFLTRGRGDKKLWSLDNANVL-ATSRFWRKVMTETfkEFPDLKV-
190 UniRef50_Q0V3G8 Putative uncharacterized pr... 81 2e-14 1 16.8% 7:161 22:184 ------DEMTRIiqVIKDKFIHPYLDIDLKYYDLGLEYRDETNDQVTL--DAAEAIKKYSVGVKCATITPDEQRVesPNGTIRNHLGGTVFRApiPAIPRLVPSWKQP----IIIGRHAFGDQYRAKDRVIDTEGTLEMVFTPkkPEVIKVYDFPAEGGVA-------------------------------------------------------------
191 UniRef50_Q0ZQ47 FrbB n=1 Tax=Streptomyces r... 79 1e-13 1 19.9% 12:212 22:199 -----------VLPAALELLESAGLTANWR-IVAGQAP---DGDGGRKPE----------AGLLPPFAEP-GASAYGLARAARRAWGGT-----FSVIERRGPLVRSDGTVNVLLFRYELDMSDTGMEFESNSGEQLALVKTAAE---LGPREIPEQAALGIQAIAPDRVSEFVRTAVGMCRRLDVDDLVVAHKGNSIKHTDGLFALTAAET----------
192 UniRef50_Q4V533 IP13250p (Fragment) n=8 Tax... 79 1e-13 1 14.0% 14:192 80:218 -------------QFVSSLLSSSRVPVEVQVIEAGQD------------DEYFHSVLRNRTAV--HVDNQADAEAKQKALKICNDLDLYVFKTRTRSFPGFKCRFP---GVDIQLIGQNNMGIFNELEYSPVEGVVE-----------------------ALSVVSQKGNDKYLRYAFKAAAKAGRKRVTLI------------------------------
193 UniRef50_C7GAF7 3-isopropylmalate dehydroge... 73 9e-12 1 21.4% 1:98 13:115 IGPEIVAEAKKVLDKIGTKY---GHSFLYEAILMGGCSIDATGVP--LTDEAIAAAKASDAVLMGSIGGNTATSPwaGLLKLRKSLNLFANLRPAYLY----------------------------------------------------------------------------------------------------------------------------
194 UniRef50_B6QD56 Putative uncharacterized pr... 63 8e-09 1 20.9% 1:86 19:101 IGPEVVNVIIDVLKSLQEILST--YRLEFTELDWGTARYKRTGK--YMPADGLSTLKTFHAGIFGAVGAPGMkcIRRLDFGVRRTF----------------------------------------------------------------------------------------------------------------------------------------
195 UniRef50_UPI0001792E94 PREDICTED: similar to AGAP0... 60 4e-08 1 18.0% 3:91 77:157 --PELMNSVQTVLKAI-------GAPIDFETILFS----EVQHSSSAKVEDVIKSINRNRICLMGALMSPDvgELQNLHMKLRKGLDLIAN-----------------------------------------------------------------------------------------------------------------------------------
196 UniRef50_C1GSN2 3-isopropylmalate dehydroge... 60 5e-08 1 13.5% 1:89 373:462 IGLEITAEAVKVLSA----FSLKKRTFDLRSELIDGCSIDTDGTP--ITKTVIQAALDSDAVLFASVGGPKWdgPEGGLLQLRKAMNQW-------------------------------------------------------------------------------------------------------------------------------------
197 UniRef50_Q8T494 AT08722p n=1 Tax=Drosophila... 57 4e-07 1 18.1% 147:218 4:75 --------------------------------------------------------------------------------------------------------------------------------------------------FNELEYSPVEGVVEALSVVSQKGNDKYLRYAFKAAAKAGRKRVTLINKAKEWPISDGSLVEAAQRLHCHYKD----
198 UniRef50_Q1G324 Putative uncharacterized pr... 57 5e-07 1 19.5% 1:82 51:127 VGNEVIPVAVDVLCLAGSL---EGIDFSFEELPIGGVALDLVGVP--LPKETLIRAKQSDALLLGAVGWYGIITITFVHLKF--------------------------------------------------------------------------------------------------------------------------------------------
199 UniRef50_A8PW52 Probable isocitrate dehydro... 56 1e-06 1 21.6% 1:74 36:100 IGPEISSSVQKIFEAA-------NAPIEWDPVDV--TPVKGDDGIFRIPSKCIELMRINKIGLKGPLATPNWQR----------------------------------------------------------------------------------------------------------------------------------------------------
200 UniRef50_B5X9F9 Isocitrate dehydrogenase, m... 54 3e-06 1 17.0% 7:94 56:151 ------DEMTRIieFIKEKLILSNVDVELKYYDLGLPYRDQTDDQVTI--DSAIATQKYHVAVKCATITPDEQRVesPNGTIRNILGGTVFREP--------------------------------------------------------------------------------------------------------------------------------
201 UniRef50_D1Z545 Whole genome shotgun sequen... 50 6e-05 1 39.4% 188:220 79:111 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KVTCIHKANIMKLADGLFHGTFNRLAKDFPQLE--
202 UniRef50_B8P335 Predicted protein (Fragment... 48 2e-04 1 21.4% 1:70 19:77 IGNEITDSVKEIFEYV-------NAPIEWEQYNVSGMS----SAGEDLFKQAVESLRRNRVGLKGILFTP--------------------------------------------------------------------------------------------------------------------------------------------------------
203 UniRef50_UPI0001AF5761 3-isopropylmalate dehydroge... 46 9e-04 1 23.3% 1:43 20:59 IGPEIMTEAVKVLELANEKYQLG---FELTHDVIGGAAIDKHG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
204 UniRef50_A1D5P0 Isocitrate dehydrogenase fa... 43 0.009 1 15.7% 2:211 15:195 -GPELTAIFERVIQSLAARYNVSVTFLRSPRIYNSYSSLLAINDADAVTEETLSDAAHYRQFCKEAVSCGVRAIFrqALYLVREQLQA------IKVEHFTLSPTSS-----ILLVRDQAQGFYSGTN----------------------SVNTSKDAVSRTAHFSKAIFARILSYALGRANQlgTNSVTMVYKFHLF---DGLFHTWATE-----------
205 UniRef50_C6HDM5 Predicted protein n=1 Tax=A... 43 0.010 1 10.6% 99:211 79:162 --------------------------------------------------------------------------------------------------PRSSLRGCQPRGFNWVIVPENPEGEYSGHSGRSHASKLWE------------------------MLIT-SGLSKIA-----YQLLRGpkHIAIATKSNAQRNGLVIWNEVAAE-----------
206 UniRef50_A3RRN5 Tartrate dehydrogenase n=3 ... 42 0.013 1 21.9% 1:73 14:82 IGKEAVPERLRVPDAAARRF---GFALHCGHFdaSSDTRARHGKLR--PDDRFDTLRGYDALFFGAVGRPDTG-----------------------------------------------------------------------------------------------------------------------------------------------------
207 UniRef50_D2H627 Putative uncharacterized pr... 40 0.046 1 14.1% 36:106 104:185 -----------------------------------SEIENHDATNDQVTKDAAEAIKKYNAGVKCAAITPDEKRVesPNGTIRNILGGTVFriICKNIPRLASDVR--------------------------------------------------------------------------------------------------------------------
208 UniRef50_Q4VCC2 Isocitrate dehydrogenase (F... 40 0.063 1 22.0% 166:215 1:49 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------TDESIYSFAEASMTTAYEKKWP-LYLSTKNTILKKYDGRFKDIFQEVYEK-------
consensus/100% ..............................................................................................................................................................................................................................
consensus/90% ...........hh...............h....h................t....h.t..hhhhs.h.........t....hR..ht.h.....h.................h.hhh....s.a...............................................th.t..h..t.......h....p...........................
consensus/80% .G.-h..thhtlhp.h..........hph..h.hu.t.h...s....h..pshtthtt.tshlhushtt....t..t..h.lRpthshasshpshh.h.t..........hshhhhRc..ts.Y.s.t................................t...hst.t..chhchuhphA.tt..t.lh.hpKsshh.....ha.phh.th.tt......
consensus/70% lG.Elhttshplhphh.......th.hpht.h.hu.thhpt.st...hstpshpthpp.cshlhGslsss...t.psh.htlRpthshasslRPsp.h.sh........thDhhllREssts.Y.u.th........ ...........s.shthhopttspRlhchAhphAhtp.htplshhpKsNlhthstthahphhtchstpa.th..
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