Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP05707
DateThu Jan 5 10:58:50 GMT 2012
Unique Job ID6d708df297e7106b

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3sjuA_
Top template information
PDB header:oxidoreductase
Chain: A: PDB Molecule:keto reductase;
PDBTitle: hedamycin polyketide ketoreductase bound to nadph
Confidence and coverage
Confidence:100.0% Coverage: 98%
254 residues ( 98% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MNQVAVVIGGGQTLGAFLCHGLAAEGYRVAVVDIQSDKAANVAQEINAEYGESMAYGFGA
Secondary structure 
SS confidence 
Disorder  ??
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  DATSEQSVLALSRGVDEIFGRVDLLVYSAGIAKAAFISDFQLGDFDRSLQVNLVGYFLCA
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  REFSRLMIRDGIQGRIIQINSKSGKVGSKHNSGYSAAKFGGVGLTQSLALDLAEYGITVH
Secondary structure 
SS confidence 
Disorder 
??
?
???
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  SLMLGNLLKSPMFQSLLPQYATKLGIKPDQVEQYYIDKVPLKRGCDYQDVLNMLLFYASP
Secondary structure 
SS confidence 
Disorder 
???
??????
Disorder confidence 
 
   .........250.........
Sequence  KASYCTGQSINVTGGQVMF
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3sju chain A

3D model

Region: 3 - 259
Aligned: 254
Modelled: 257
Confidence: 100.0%
Identity: 30%
PDB header:oxidoreductase
Chain: A: PDB Molecule:keto reductase;
PDBTitle: hedamycin polyketide ketoreductase bound to nadph

Phyre2

PDB 2rhc chain A domain 1

3D model

Region: 2 - 259
Aligned: 255
Modelled: 258
Confidence: 100.0%
Identity: 29%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 3lf2 chain B

3D model

Region: 2 - 259
Aligned: 256
Modelled: 258
Confidence: 100.0%
Identity: 21%
PDB header:oxidoreductase
Chain: B: PDB Molecule:short chain oxidoreductase q9hya2;
PDBTitle: nadph bound structure of the short chain oxidoreductase q9hya2 from2 pseudomonas aeruginosa pao1 containing an atypical catalytic center

Phyre2

PDB 1iy8 chain A

3D model

Region: 2 - 258
Aligned: 253
Modelled: 257
Confidence: 100.0%
Identity: 26%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1w4z chain A

3D model

Region: 2 - 259
Aligned: 256
Modelled: 258
Confidence: 100.0%
Identity: 24%
PDB header:antibiotic biosynthesis
Chain: A: PDB Molecule:ketoacyl reductase;
PDBTitle: structure of actinorhodin polyketide (actiii) reductase

Phyre2

PDB 1geg chain A

3D model

Region: 3 - 258
Aligned: 253
Modelled: 256
Confidence: 100.0%
Identity: 31%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1k2w chain A

3D model

Region: 1 - 258
Aligned: 252
Modelled: 258
Confidence: 100.0%
Identity: 28%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 3ak4 chain C

3D model

Region: 1 - 258
Aligned: 252
Modelled: 258
Confidence: 100.0%
Identity: 31%
PDB header:oxidoreductase
Chain: C: PDB Molecule:nadh-dependent quinuclidinone reductase;
PDBTitle: crystal structure of nadh-dependent quinuclidinone reductase from2 agrobacterium tumefaciens

Phyre2

PDB 3svt chain A

3D model

Region: 2 - 258
Aligned: 247
Modelled: 257
Confidence: 100.0%
Identity: 26%
PDB header:oxidoreductase
Chain: A: PDB Molecule:short-chain type dehydrogenase/reductase;
PDBTitle: structure of a short-chain type dehydrogenase/reductase from2 mycobacterium ulcerans

Phyre2

PDB 2cfc chain B

3D model

Region: 1 - 258
Aligned: 247
Modelled: 249
Confidence: 100.0%
Identity: 24%
PDB header:oxidoreductase
Chain: B: PDB Molecule:2-(r)-hydroxypropyl-com dehydrogenase;
PDBTitle: structural basis for stereo selectivity in the (r)- and2 (s)-hydroxypropylethane thiosulfonate dehydrogenases

Phyre2

PDB 3rih chain B

3D model

Region: 2 - 259
Aligned: 245
Modelled: 258
Confidence: 100.0%
Identity: 23%
PDB header:oxidoreductase
Chain: B: PDB Molecule:short chain dehydrogenase or reductase;
PDBTitle: crystal structure of a putative short chain dehydrogenase or reductase2 from mycobacterium abscessus

Phyre2

PDB 1yxm chain A domain 1

3D model

Region: 2 - 259
Aligned: 248
Modelled: 251
Confidence: 100.0%
Identity: 24%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1gee chain A

3D model

Region: 2 - 259
Aligned: 246
Modelled: 258
Confidence: 100.0%
Identity: 26%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1zem chain A domain 1

3D model

Region: 2 - 255
Aligned: 251
Modelled: 254
Confidence: 100.0%
Identity: 25%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1w6u chain A

3D model

Region: 2 - 258
Aligned: 241
Modelled: 243
Confidence: 100.0%
Identity: 20%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1xhl chain A

3D model

Region: 2 - 259
Aligned: 255
Modelled: 258
Confidence: 100.0%
Identity: 14%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 2ae2 chain A

3D model

Region: 2 - 257
Aligned: 247
Modelled: 256
Confidence: 100.0%
Identity: 19%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1h5q chain A

3D model

Region: 1 - 259
Aligned: 246
Modelled: 259
Confidence: 100.0%
Identity: 24%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1g0o chain A

3D model

Region: 2 - 258
Aligned: 253
Modelled: 257
Confidence: 100.0%
Identity: 24%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 3cxt chain A

3D model

Region: 2 - 259
Aligned: 239
Modelled: 243
Confidence: 100.0%
Identity: 24%
PDB header:oxidoreductase
Chain: A: PDB Molecule:dehydrogenase with different specificities;
PDBTitle: quaternary complex structure of gluconate 5-dehydrogenase from2 streptococcus suis type 2

Phyre2
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c3sjuA_
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d2rhca1
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c3lf2B_
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d1iy8a_
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c1w4zA_
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d1gega_
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d1k2wa_
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c3ak4C_
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c3svtA_
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c2cfcB_
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c3rihB_
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d1yxma1
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d1geea_
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d1zema1
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d1w6ua_
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d1xhla_
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d2ae2a_
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d1h5qa_
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d1g0oa_
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c3cxtA_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3sjuA_
100.0 30 PDB header:oxidoreductase
Chain: A: PDB Molecule:keto reductase;
PDBTitle: hedamycin polyketide ketoreductase bound to nadph
2d2rhca1
100.0 29 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
3c3lf2B_
100.0 21 PDB header:oxidoreductase
Chain: B: PDB Molecule:short chain oxidoreductase q9hya2;
PDBTitle: nadph bound structure of the short chain oxidoreductase q9hya2 from2 pseudomonas aeruginosa pao1 containing an atypical catalytic center
4d1iy8a_
100.0 26 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
5c1w4zA_
100.0 24 PDB header:antibiotic biosynthesis
Chain: A: PDB Molecule:ketoacyl reductase;
PDBTitle: structure of actinorhodin polyketide (actiii) reductase
6d1gega_
100.0 31 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
7d1k2wa_
100.0 28 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
8c3ak4C_
100.0 31 PDB header:oxidoreductase
Chain: C: PDB Molecule:nadh-dependent quinuclidinone reductase;
PDBTitle: crystal structure of nadh-dependent quinuclidinone reductase from2 agrobacterium tumefaciens
9c3svtA_
100.0 26 PDB header:oxidoreductase
Chain: A: PDB Molecule:short-chain type dehydrogenase/reductase;
PDBTitle: structure of a short-chain type dehydrogenase/reductase from2 mycobacterium ulcerans
10c2cfcB_
100.0 24 PDB header:oxidoreductase
Chain: B: PDB Molecule:2-(r)-hydroxypropyl-com dehydrogenase;
PDBTitle: structural basis for stereo selectivity in the (r)- and2 (s)-hydroxypropylethane thiosulfonate dehydrogenases
11c3rihB_
100.0 23 PDB header:oxidoreductase
Chain: B: PDB Molecule:short chain dehydrogenase or reductase;
PDBTitle: crystal structure of a putative short chain dehydrogenase or reductase2 from mycobacterium abscessus
12d1yxma1
100.0 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
13d1geea_
100.0 26 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
14d1zema1
100.0 25 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
15d1w6ua_
100.0 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
16d1xhla_
100.0 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
17d2ae2a_
100.0 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
18d1h5qa_
100.0 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
19d1g0oa_
100.0 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
20c3cxtA_
100.0 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:dehydrogenase with different specificities;
PDBTitle: quaternary complex structure of gluconate 5-dehydrogenase from2 streptococcus suis type 2
21c3pk0B_
not modelled 100.0 23 PDB header:oxidoreductase
Chain: B: PDB Molecule:short-chain dehydrogenase/reductase sdr;
PDBTitle: crystal structure of short-chain dehydrogenase/reductase sdr from2 mycobacterium smegmatis
22d1ae1a_
not modelled 100.0 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
23c3toxG_
not modelled 100.0 22 PDB header:oxidoreductase
Chain: G: PDB Molecule:short chain dehydrogenase;
PDBTitle: crystal structure of a short chain dehydrogenase in complex with2 nad(p) from sinorhizobium meliloti 1021
24c3itdA_
not modelled 100.0 25 PDB header:oxidoreductase
Chain: A: PDB Molecule:17beta-hydroxysteroid dehydrogenase;
PDBTitle: crystal structure of an inactive 17beta-hydroxysteroid dehydrogenase2 (y167f mutated form) from fungus cochliobolus lunatus
25d1fmca_
not modelled 100.0 28 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
26c3ai3A_
not modelled 100.0 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadph-sorbose reductase;
PDBTitle: the crystal structure of l-sorbose reductase from gluconobacter2 frateurii complexed with nadph and l-sorbose
27c2zatC_
not modelled 100.0 22 PDB header:oxidoreductase
Chain: C: PDB Molecule:dehydrogenase/reductase sdr family member 4;
PDBTitle: crystal structure of a mammalian reductase
28d1xkqa_
not modelled 100.0 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
29d1ja9a_
not modelled 100.0 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
30d2bgka1
not modelled 100.0 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
31c3nugA_
not modelled 100.0 31 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-(acyl-carrier protein) reductase;
PDBTitle: crystal structure of wild type tetrameric pyridoxal 4-dehydrogenase2 from mesorhizobium loti
32c3gk3D_
not modelled 100.0 30 PDB header:oxidoreductase
Chain: D: PDB Molecule:acetoacetyl-coa reductase;
PDBTitle: crystal structure of acetoacetyl-coa reductase from2 burkholderia pseudomallei 1710b
33c3t7cC_
not modelled 100.0 24 PDB header:oxidoreductase
Chain: C: PDB Molecule:carveol dehydrogenase;
PDBTitle: crystal structure of carveol dehydrogenase from mycobacterium avium2 bound to nad
34d1hdca_
not modelled 100.0 28 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
35c3imfA_
not modelled 100.0 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:short chain dehydrogenase;
PDBTitle: 1.99 angstrom resolution crystal structure of a short chain2 dehydrogenase from bacillus anthracis str. 'ames ancestor'
36c3gvcB_
not modelled 100.0 28 PDB header:oxidoreductase
Chain: B: PDB Molecule:probable short-chain type
PDBTitle: crystal structure of probable short-chain dehydrogenase-2 reductase from mycobacterium tuberculosis
37c3pgxB_
not modelled 100.0 26 PDB header:oxidoreductase
Chain: B: PDB Molecule:carveol dehydrogenase;
PDBTitle: crystal structure of a putative carveol dehydrogenase from2 mycobacterium paratuberculosis bound to nicotinamide adenine3 dinucleotide
38c2q2qG_
not modelled 100.0 28 PDB header:oxidoreductase
Chain: G: PDB Molecule:beta-d-hydroxybutyrate dehydrogenase;
PDBTitle: structure of d-3-hydroxybutyrate dehydrogenase from pseudomonas putida
39d1q7ba_
not modelled 100.0 29 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
40c2c07A_
not modelled 100.0 28 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-(acyl-carrier protein) reductase;
PDBTitle: oxoacyl-acp reductase of plasmodium falciparum
41d2c07a1
not modelled 100.0 28 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
42c3iccA_
not modelled 100.0 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative 3-oxoacyl-(acyl carrier protein) reductase;
PDBTitle: crystal structure of a putative 3-oxoacyl-(acyl carrier protein)2 reductase from bacillus anthracis at 1.87 a resolution
43c3gr6A_
not modelled 100.0 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:enoyl-[acyl-carrier-protein] reductase [nadh];
PDBTitle: crystal structure of the staphylococcus aureus enoyl-acyl2 carrier protein reductase (fabi) in complex with nadp and3 triclosan
44d1pr9a_
not modelled 100.0 25 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
45c3ijrF_
not modelled 100.0 20 PDB header:oxidoreductase
Chain: F: PDB Molecule:oxidoreductase, short chain dehydrogenase/reductase family;
PDBTitle: 2.05 angstrom resolution crystal structure of a short chain2 dehydrogenase from bacillus anthracis str. 'ames ancestor' in complex3 with nad+
46c3o38D_
not modelled 100.0 25 PDB header:oxidoreductase
Chain: D: PDB Molecule:short chain dehydrogenase;
PDBTitle: crystal structure of a short chain dehydrogenase from mycobacterium2 smegmatis
47c2pd6D_
not modelled 100.0 31 PDB header:oxidoreductase
Chain: D: PDB Molecule:estradiol 17-beta-dehydrogenase 8;
PDBTitle: structure of human hydroxysteroid dehydrogenase type 8, hsd17b8
48c3k31B_
not modelled 100.0 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:enoyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal structure of eonyl-(acyl-carrier-protein) reductase from2 anaplasma phagocytophilum in complex with nad at 1.9a resolution
49c3ezlA_
not modelled 100.0 25 PDB header:oxidoreductase
Chain: A: PDB Molecule:acetoacetyl-coa reductase;
PDBTitle: crystal structure of acetyacetyl-coa reductase from2 burkholderia pseudomallei 1710b
50d1ydea1
not modelled 100.0 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
51d1zk4a1
not modelled 100.0 26 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
52d2pd4a1
not modelled 100.0 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
53c2p68A_
not modelled 100.0 33 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase;
PDBTitle: crystal structure of aq_1716 from aquifex aeolicus vf5
54c3rkuC_
not modelled 100.0 16 PDB header:oxidoreductase
Chain: C: PDB Molecule:oxidoreductase ymr226c;
PDBTitle: substrate fingerprint and the structure of nadp+ dependent serine2 dehydrogenase from saccharomyces cerevisiae complexed with nadp+
55c3r3sD_
not modelled 100.0 21 PDB header:oxidoreductase
Chain: D: PDB Molecule:oxidoreductase;
PDBTitle: structure of the ygha oxidoreductase from salmonella enterica
56c2uvdE_
not modelled 100.0 31 PDB header:oxidoreductase
Chain: E: PDB Molecule:3-oxoacyl-(acyl-carrier-protein) reductase;
PDBTitle: the crystal structure of a 3-oxoacyl-(acyl carrier protein)2 reductase from bacillus anthracis (ba3989)
57d1x1ta1
not modelled 100.0 31 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
58c3oidA_
not modelled 100.0 23 PDB header:oxidoreductase
Chain: A: PDB Molecule:enoyl-[acyl-carrier-protein] reductase [nadph];
PDBTitle: crystal structure of enoyl-acp reductases iii (fabl) from b. subtilis2 (complex with nadp and tcl)
59c3uf0A_
not modelled 100.0 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:short-chain dehydrogenase/reductase sdr;
PDBTitle: crystal structure of a putative nad(p) dependent gluconate 5-2 dehydrogenase from beutenbergia cavernae(efi target efi-502044) with3 bound nadp (low occupancy)
60c3bmrA_
not modelled 100.0 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:pteridine reductase;
PDBTitle: structure of pteridine reductase 1 (ptr1) from trypanosoma2 brucei in ternary complex with cofactor (nadp+) and3 inhibitor (compound ax6)
61c3ftpD_
not modelled 100.0 29 PDB header:oxidoreductase
Chain: D: PDB Molecule:3-oxoacyl-[acyl-carrier protein] reductase;
PDBTitle: crystal structure of 3-ketoacyl-(acyl-carrier-protein)2 reductase from burkholderia pseudomallei at 2.05 a3 resolution
62d1edoa_
not modelled 100.0 31 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
63c3grkE_
not modelled 100.0 16 PDB header:oxidoreductase
Chain: E: PDB Molecule:enoyl-(acyl-carrier-protein) reductase (nadh);
PDBTitle: crystal structure of short chain dehydrogenase reductase2 sdr glucose-ribitol dehydrogenase from brucella melitensis
64c2z1nA_
not modelled 100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:dehydrogenase;
PDBTitle: crystal structure of ape0912 from aeropyrum pernix k1
65c2qioA_
not modelled 100.0 18 PDB header:unknown function
Chain: A: PDB Molecule:enoyl-(acyl-carrier-protein) reductase;
PDBTitle: x-ray structure of enoyl-acyl carrier protein reductase from bacillus2 anthracis with triclosan
66c3uveC_
not modelled 100.0 25 PDB header:oxidoreductase
Chain: C: PDB Molecule:carveol dehydrogenase ((+)-trans-carveol dehydrogenase);
PDBTitle: crystal structure of carveol dehydrogenase ((+)-trans-carveol2 dehydrogenase) from mycobacterium avium
67c3emkA_
not modelled 100.0 32 PDB header:oxidoreductase
Chain: A: PDB Molecule:glucose/ribitol dehydrogenase;
PDBTitle: 2.5a crystal structure of glucose/ribitol dehydrogenase2 from brucella melitensis
68c3v8bC_
not modelled 100.0 22 PDB header:oxidoreductase
Chain: C: PDB Molecule:putative dehydrogenase, possibly 3-oxoacyl-[acyl-carrier
PDBTitle: crystal structure of a 3-ketoacyl-acp reductase from sinorhizobium2 meliloti 1021
69c2p91A_
not modelled 100.0 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:enoyl-[acyl-carrier-protein] reductase [nadh];
PDBTitle: crystal structure of enoyl-[acyl-carrier-protein] reductase (nadh)2 from aquifex aeolicus vf5
70c2wdzD_
not modelled 100.0 22 PDB header:oxidoreductase
Chain: D: PDB Molecule:short-chain dehydrogenase/reductase;
PDBTitle: crystal structure of the short chain dehydrogenase2 galactitol-dehydrogenase (gatdh) of rhodobacter3 sphaeroides in complex with nad+ and 1,2-pentandiol
71c3ek2D_
not modelled 100.0 17 PDB header:oxidoreductase
Chain: D: PDB Molecule:enoyl-(acyl-carrier-protein) reductase (nadh);
PDBTitle: crystal structure of eonyl-(acyl carrier protein) reductase2 from burkholderia pseudomallei 1719b
72d1vl8a_
not modelled 100.0 30 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
73d1qsga_
not modelled 100.0 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
74c3oecA_
not modelled 100.0 28 PDB header:oxidoreductase
Chain: A: PDB Molecule:carveol dehydrogenase (mytha.01326.c, a0r518 homolog);
PDBTitle: crystal structure of carveol dehydrogenase from mycobacterium2 thermoresistibile
75c3osuA_
not modelled 100.0 33 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase;
PDBTitle: crystal structure of the 3-oxoacyl-acyl carrier protein reductase,2 fabg, from staphylococcus aureus
76c2ph3B_
not modelled 100.0 30 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-oxoacyl-[acyl carrier protein] reductase;
PDBTitle: crystal structure of 3-oxoacyl-[acyl carrier protein] reductase2 ttha0415 from thermus thermophilus
77c3i4fD_
not modelled 100.0 19 PDB header:oxidoreductase
Chain: D: PDB Molecule:3-oxoacyl-[acyl-carrier protein] reductase;
PDBTitle: structure of putative 3-oxoacyl-reductase from bacillus thuringiensis
78d1hxha_
not modelled 100.0 27 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
79c3v2gA_
not modelled 100.0 28 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase;
PDBTitle: crystal structure of a dehydrogenase/reductase from sinorhizobium2 meliloti 1021
80d1nffa_
not modelled 100.0 35 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
81d1mxha_
not modelled 100.0 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
82c3lylB_
not modelled 100.0 27 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-oxoacyl-(acyl-carrier-protein) reductase;
PDBTitle: structure of 3-oxoacyl-acylcarrier protein reductase, fabg2 from francisella tularensis
83d1o5ia_
not modelled 100.0 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
84c2b4qB_
not modelled 100.0 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:rhamnolipids biosynthesis 3-oxoacyl-[acyl-
PDBTitle: pseudomonas aeruginosa rhlg/nadp active-site complex
85c3afnC_
not modelled 100.0 17 PDB header:oxidoreductase
Chain: C: PDB Molecule:carbonyl reductase;
PDBTitle: crystal structure of aldose reductase a1-r complexed with nadp
86c2qhxB_
not modelled 100.0 24 PDB header:oxidoreductase
Chain: B: PDB Molecule:pteridine reductase 1;
PDBTitle: structure of pteridine reductase from leishmania major2 complexed with a ligand
87d1bdba_
not modelled 100.0 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
88c3uxyC_
not modelled 100.0 27 PDB header:oxidoreductase
Chain: C: PDB Molecule:short-chain dehydrogenase/reductase sdr;
PDBTitle: the crystal structure of short chain dehydrogenase from rhodobacter2 sphaeroides
89c3r1iB_
not modelled 100.0 30 PDB header:oxidoreductase
Chain: B: PDB Molecule:short-chain type dehydrogenase/reductase;
PDBTitle: crystal structure of a short-chain type dehydrogenase/reductase from2 mycobacterium marinum
90d1ulsa_
not modelled 100.0 28 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
91d1ulua_
not modelled 100.0 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
92c3v2hB_
not modelled 100.0 32 PDB header:oxidoreductase
Chain: B: PDB Molecule:d-beta-hydroxybutyrate dehydrogenase;
PDBTitle: the crystal structure of d-beta-hydroxybutyrate dehydrogenase from2 sinorhizobium meliloti
93c3n74A_
not modelled 100.0 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-ketoacyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase from2 brucella melitensis
94c3a28H_
not modelled 100.0 29 PDB header:oxidoreductase
Chain: H: PDB Molecule:l-2.3-butanediol dehydrogenase;
PDBTitle: crystal structure of l-2,3-butanediol dehydrogenase
95d2ew8a1
not modelled 100.0 30 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
96c3ppiA_
not modelled 100.0 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-hydroxyacyl-coa dehydrogenase type-2;
PDBTitle: crystal structure of 3-hydroxyacyl-coa dehydrogenase type-2 from2 mycobacterium avium
97c3gdfA_
not modelled 100.0 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:probable nadp-dependent mannitol dehydrogenase;
PDBTitle: crystal structure of the nadp-dependent mannitol dehydrogenase from2 cladosporium herbarum.
98d1p33a_
not modelled 100.0 27 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
99d2d1ya1
not modelled 100.0 29 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
100c2dteB_
not modelled 100.0 24 PDB header:oxidoreductase
Chain: B: PDB Molecule:glucose 1-dehydrogenase related protein;
PDBTitle: structure of thermoplasma acidophilum aldohexose dehydrogenase (aldt)2 in complex with nadh
101c2jjyD_
not modelled 100.0 16 PDB header:oxidoreductase
Chain: D: PDB Molecule:enoyl-[acyl-carrier-protein] reductase;
PDBTitle: crystal structure of francisella tularensis enoyl reductase2 (ftfabi) with bound nad
102d1cyda_
not modelled 100.0 26 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
103c3sx2F_
not modelled 100.0 23 PDB header:oxidoreductase
Chain: F: PDB Molecule:putative 3-ketoacyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal structure of a putative 3-ketoacyl-(acyl-carrier-protein)2 reductase from mycobacterium paratuberculosis in complex with nad
104d2ag5a1
not modelled 100.0 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
105d2h7ma1
not modelled 100.0 9 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
106d1uh5a_
not modelled 100.0 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
107c2ekqB_
not modelled 100.0 21 PDB header:oxidoreductase
Chain: B: PDB Molecule:2-deoxy-d-gluconate 3-dehydrogenase;
PDBTitle: structure of tt0495 protein from thermus thermophilus
108c3ctmH_
not modelled 100.0 18 PDB header:oxidoreductase
Chain: H: PDB Molecule:carbonyl reductase;
PDBTitle: crystal structure of a carbonyl reductase from candida2 parapsilosis with anti-prelog stereo-specificity
109c2et6A_
not modelled 100.0 26 PDB header:oxidoreductase
Chain: A: PDB Molecule:(3r)-hydroxyacyl-coa dehydrogenase;
PDBTitle: (3r)-hydroxyacyl-coa dehydrogenase domain of candida tropicalis2 peroxisomal multifunctional enzyme type 2
110d1e6wa_
not modelled 100.0 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
111c2nm0B_
not modelled 100.0 28 PDB header:oxidoreductase
Chain: B: PDB Molecule:probable 3-oxacyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal structure of sco1815: a beta-ketoacyl-acyl carrier protein2 reductase from streptomyces coelicolor a3(2)
112d2a4ka1
not modelled 100.0 25 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
113c3pxxE_
not modelled 100.0 21 PDB header:oxidoreductase
Chain: E: PDB Molecule:carveol dehydrogenase;
PDBTitle: crystal structure of carveol dehydrogenase from mycobacterium avium2 bound to nicotinamide adenine dinucleotide
114d2gdza1
not modelled 100.0 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
115d1spxa_
not modelled 100.0 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
116d1xg5a_
not modelled 100.0 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
117c3t4xA_
not modelled 100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase, short chain dehydrogenase/reductase family;
PDBTitle: short chain dehydrogenase/reductase family oxidoreductase from2 bacillus anthracis str. ames ancestor
118c3llsB_
not modelled 100.0 29 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-ketoacyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase from2 mycobacterium tuberculosis
119c3diiB_
not modelled 100.0 27 PDB header:oxidoreductase
Chain: B: PDB Molecule:short-chain dehydrogenase/reductase sdr;
PDBTitle: crystal structure of a carbohydrate specific scor enzyme2 from clostridium thermocellum, ligand-free form
120d1uaya_
not modelled 100.0 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0