Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	T	G	S	E	F	H	V	G	I	V	G	L	G	S	M	G	M	G	A	A	L	S	Y	V	R	A	G	L	S	T	W	G	A	D	L	N	S	N	A	C	A	T	L	K	E	A	G	A	C	G	V	S	D	N	A	A	T	F
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	E	K	L	D	A	L	L	V	L	V	V	N	A	A	Q	V	K	Q	V	L	F	G	E	T	G	V	A	Q	H	L	K	P	G	T	A	V	M	V	S	S	T	I	A	S	A	D	A	Q	E	I	A	T	A	L	A	G	F	D	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		E	M	L	D	A	P	V	S	G	G	A	V	K	A	A	N	G	E	M	T	V	M	A	S	G	S	D	I	A	F	E	R	L	A	P	V	L	E	A	V	A	G	K	V	Y	R	I	G	A	E	P	G	L	G	S	T	V	K	I	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		H	Q	L	L	A	G	V	H	I	A	A	G	A	E	A	M	A	L	A	A	R	A	G	I	P	L	D	V	M	Y	D	V	V	T	N	A	A	G	N	S	W	M	F	E	N	R	M	R	H	V	V	D	G	D	Y	T	P	H	S	A
Secondary structure
SS confidence
Disorder																																																								?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		V	D	I	F	V	K	D	L	G	L	V	A	D	T	A	K	A	L	H	F	P	L	P	L	A	S	T	A	L	N	M	F	T	S	A	S	N	A	G	Y	G	K	E	D	D	S	A	V	I	K	I	F	S	G	I	T	L	P	G	A
Secondary structure
SS confidence
Disorder																																							?	?	?	?	?															?	?	?	?
Disorder confidence
		.	.
Sequence		K	S
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1yb4 chain A Region: 8 - 294 Aligned: 284 Modelled: 286 Confidence: 100.0% Identity: 26% PDB header:oxidoreductase Chain: A: PDB Molecule:tartronic semialdehyde reductase; PDBTitle: crystal structure of the tartronic semialdehyde reductase from2 salmonella typhimurium lt2 Phyre2 PDB 3cum chain A Region: 8 - 296 Aligned: 287 Modelled: 288 Confidence: 100.0% Identity: 29% PDB header:oxidoreductase Chain: A: PDB Molecule:probable 3-hydroxyisobutyrate dehydrogenase; PDBTitle: crystal structure of a possible 3-hydroxyisobutyrate dehydrogenase2 from pseudomonas aeruginosa pao1 Phyre2 PDB 1vpd chain A Region: 8 - 294 Aligned: 285 Modelled: 286 Confidence: 100.0% Identity: 32% PDB header:oxidoreductase Chain: A: PDB Molecule:tartronate semialdehyde reductase; PDBTitle: x-ray crystal structure of tartronate semialdehyde reductase2 [salmonella typhimurium lt2] Phyre2 PDB 3g0o chain A Region: 6 - 292 Aligned: 285 Modelled: 287 Confidence: 100.0% Identity: 78% PDB header:oxidoreductase Chain: A: PDB Molecule:3-hydroxyisobutyrate dehydrogenase; PDBTitle: crystal structure of 3-hydroxyisobutyrate dehydrogenase2 (ygbj) from salmonella typhimurium Phyre2 PDB 3cky chain A Region: 6 - 298 Aligned: 291 Modelled: 293 Confidence: 100.0% Identity: 31% PDB header:oxidoreductase Chain: A: PDB Molecule:2-hydroxymethyl glutarate dehydrogenase; PDBTitle: structural and kinetic properties of a beta-hydroxyacid dehydrogenase2 involved in nicotinate fermentation Phyre2 PDB 2cvz chain D Region: 8 - 301 Aligned: 286 Modelled: 293 Confidence: 100.0% Identity: 23% PDB header:oxidoreductase Chain: D: PDB Molecule:3-hydroxyisobutyrate dehydrogenase; PDBTitle: structure of hydroxyisobutyrate dehydrogenase from thermus2 thermophilus hb8 Phyre2 PDB 2uyy chain D Region: 3 - 292 Aligned: 288 Modelled: 290 Confidence: 100.0% Identity: 23% PDB header:cytokine Chain: D: PDB Molecule:n-pac protein; PDBTitle: structure of the cytokine-like nuclear factor n-pac Phyre2 PDB 3pdu chain F Region: 8 - 293 Aligned: 284 Modelled: 286 Confidence: 100.0% Identity: 27% PDB header:oxidoreductase Chain: F: PDB Molecule:3-hydroxyisobutyrate dehydrogenase family protein; PDBTitle: crystal structure of gamma-hydroxybutyrate dehydrogenase from2 geobacter sulfurreducens in complex with nadp+ Phyre2 PDB 3pef chain A Region: 8 - 294 Aligned: 284 Modelled: 287 Confidence: 100.0% Identity: 27% PDB header:oxidoreductase Chain: A: PDB Molecule:6-phosphogluconate dehydrogenase, nad-binding; PDBTitle: crystal structure of gamma-hydroxybutyrate dehydrogenase from2 geobacter metallireducens in complex with nadp+ Phyre2 PDB 3doj chain A Region: 7 - 293 Aligned: 285 Modelled: 287 Confidence: 100.0% Identity: 24% PDB header:oxidoreductase Chain: A: PDB Molecule:dehydrogenase-like protein; PDBTitle: structure of glyoxylate reductase 1 from arabidopsis2 (atglyr1) Phyre2 PDB 3l6d chain B Region: 3 - 294 Aligned: 287 Modelled: 290 Confidence: 100.0% Identity: 17% PDB header:oxidoreductase Chain: B: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of putative oxidoreductase from pseudomonas putida2 kt2440 Phyre2 PDB 2gf2 chain B Region: 7 - 294 Aligned: 286 Modelled: 288 Confidence: 100.0% Identity: 28% PDB header:oxidoreductase Chain: B: PDB Molecule:3-hydroxyisobutyrate dehydrogenase; PDBTitle: crystal structure of human hydroxyisobutyrate dehydrogenase Phyre2 PDB 3fwn chain B Region: 5 - 271 Aligned: 261 Modelled: 264 Confidence: 100.0% Identity: 21% PDB header:oxidoreductase Chain: B: PDB Molecule:6-phosphogluconate dehydrogenase, decarboxylating; PDBTitle: dimeric 6-phosphogluconate dehydrogenase complexed with 6-2 phosphogluconate and 2'-monophosphoadenosine-5'-diphosphate Phyre2 PDB 2p4q chain A Region: 5 - 271 Aligned: 262 Modelled: 264 Confidence: 100.0% Identity: 21% PDB header:oxidoreductase Chain: A: PDB Molecule:6-phosphogluconate dehydrogenase, decarboxylating 1; PDBTitle: crystal structure analysis of gnd1 in saccharomyces cerevisiae Phyre2 PDB 1pgj chain A Region: 6 - 271 Aligned: 261 Modelled: 266 Confidence: 100.0% Identity: 23% PDB header:oxidoreductase Chain: A: PDB Molecule:6-phosphogluconate dehydrogenase; PDBTitle: x-ray structure of 6-phosphogluconate dehydrogenase from the protozoan2 parasite t. brucei Phyre2 PDB 1pgq chain A Region: 5 - 271 Aligned: 262 Modelled: 266 Confidence: 100.0% Identity: 18% PDB header:oxidoreductase (choh(d)-nadp+(a)) Chain: A: PDB Molecule:6-phosphogluconate dehydrogenase; PDBTitle: crystallographic study of coenzyme, coenzyme analogue and substrate2 binding in 6-phosphogluconate dehydrogenase: implications for nadp3 specificity and the enzyme mechanism Phyre2 PDB 2iz1 chain C Region: 5 - 271 Aligned: 262 Modelled: 264 Confidence: 100.0% Identity: 21% PDB header:oxidoreductase Chain: C: PDB Molecule:6-phosphogluconate dehydrogenase, decarboxylating; PDBTitle: 6pdh complexed with pex inhibitor synchrotron data Phyre2 PDB 3qha chain B Region: 6 - 281 Aligned: 270 Modelled: 276 Confidence: 100.0% Identity: 30% PDB header:oxidoreductase Chain: B: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of a putative oxidoreductase from mycobacterium2 avium 104 Phyre2 PDB 3qsg chain A Region: 8 - 294 Aligned: 274 Modelled: 287 Confidence: 100.0% Identity: 16% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:nad-binding phosphogluconate dehydrogenase-like protein; PDBTitle: crystal structure of nad-binding phosphogluconate dehydrogenase-like2 protein from alicyclobacillus acidocaldarius Phyre2 PDB 2y0d chain B Region: 6 - 274 Aligned: 259 Modelled: 269 Confidence: 100.0% Identity: 16% PDB header:oxidoreductase Chain: B: PDB Molecule:udp-glucose dehydrogenase; PDBTitle: bcec mutation y10k Phyre2 1 c1yb4A_ 2 c3cumA_ 3 c1vpdA_ 4 c3g0oA_ 5 c3ckyA_ 6 c2cvzD_ 7 c2uyyD_ 8 c3pduF_ 9 c3pefA_ 10 c3dojA_ 11 c3l6dB_ 12 c2gf2B_ 13 c3fwnB_ 14 c2p4qA_ 15 c1pgjA_ 16 c1pgqA_ 17 c2iz1C_ 18 c3qhaB_ 19 c3qsgA_ 20 c2y0dB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499