Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	Q	F	A	F	V	F	P	G	Q	G	S	Q	T	V	G	M	L	A	D	M	A	A	S	Y	P	I	V	E	E	T	F	A	E	A	S	A	A	L	G	Y	D	L	W	A	L	T	Q	Q	G	P	A	E	E	L	N	K	T	W
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Q	T	Q	P	A	L	L	T	A	S	V	A	L	Y	R	V	W	Q	Q	Q	G	G	K	A	P	A	M	M	A	G	H	S	L	G	E	Y	S	A	L	V	C	A	G	V	I	D	F	A	D	A	V	R	L	V	E	M	R	G	K	F
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		M	Q	E	A	V	P	E	G	T	G	A	M	A	A	I	I	G	L	D	D	A	S	I	A	K	A	C	E	E	A	A	E	G	Q	V	V	S	P	V	N	F	N	S	P	G	Q	V	V	I	A	G	H	K	E	A	V	E	R	A	G
Secondary structure
SS confidence
Disorder							?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	A	C	K	A	A	G	A	K	R	A	L	P	L	P	V	S	V	P	S	H	C	A	L	M	K	P	A	A	D	K	L	A	V	E	L	A	K	I	T	F	N	A	P	T	V	P	V	V	N	N	V	D	V	K	C	E	T	N	G
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		D	A	I	R	D	A	L	V	R	Q	L	Y	N	P	V	Q	W	T	K	S	V	E	Y	M	A	A	Q	G	V	E	H	L	Y	E	V	G	P	G	K	V	L	T	G	L	T	K	R	I	V	D	T	L	T	A	S	A	L	N	E	P
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.
Sequence		S	A	M	A	A	A	L	E	L
Secondary structure
SS confidence
Disorder									?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2g2o chain A Region: 3 - 309 Aligned: 307 Modelled: 307 Confidence: 100.0% Identity: 100% PDB header:transferase Chain: A: PDB Molecule:malonyl coa-acyl carrier protein transacylase; PDBTitle: structure of e.coli fabd complexed with sulfate Phyre2 PDB 3een chain A Region: 2 - 308 Aligned: 307 Modelled: 307 Confidence: 100.0% Identity: 54% PDB header:transferase Chain: A: PDB Molecule:malonyl coa-acp transacylase; PDBTitle: crystal structure of malonyl-coa:acyl carrier protein transacylase2 (fabd), xoo0880, from xanthomonas oryzae pv. oryzae kacc10331 Phyre2 PDB 3im8 chain A Region: 3 - 308 Aligned: 303 Modelled: 306 Confidence: 100.0% Identity: 45% PDB header:transferase Chain: A: PDB Molecule:malonyl acyl carrier protein transacylase; PDBTitle: crystal structure of mcat from streptococcus pneumoniae Phyre2 PDB 3ezo chain A Region: 3 - 309 Aligned: 306 Modelled: 307 Confidence: 100.0% Identity: 55% PDB header:transferase Chain: A: PDB Molecule:malonyl coa-acyl carrier protein transacylase; PDBTitle: crystal structure of acyl-carrier-protein s-2 malonyltransferase from burkholderia pseudomallei 1710b Phyre2 PDB 3tqe chain A Region: 2 - 307 Aligned: 306 Modelled: 306 Confidence: 100.0% Identity: 54% PDB header:transferase Chain: A: PDB Molecule:malonyl-coa-[acyl-carrier-protein] transacylase; PDBTitle: structure of the malonyl coa-acyl carrier protein transacylase (fabd)2 from coxiella burnetii Phyre2 PDB 3qat chain B Region: 4 - 308 Aligned: 304 Modelled: 305 Confidence: 100.0% Identity: 43% PDB header:transferase Chain: B: PDB Molecule:malonyl coa-acyl carrier protein transacylase; PDBTitle: crystal structure of acyl-carrier-protein-s-malonyltransferase from2 bartonella henselae Phyre2 PDB 3ptw chain A Region: 3 - 307 Aligned: 303 Modelled: 305 Confidence: 100.0% Identity: 39% PDB header:transferase Chain: A: PDB Molecule:malonyl coa-acyl carrier protein transacylase; PDBTitle: crystal structure of malonyl coa-acyl carrier protein transacylase2 from clostridium perfringens atcc 13124 Phyre2 PDB 3im9 chain A Region: 2 - 305 Aligned: 301 Modelled: 304 Confidence: 100.0% Identity: 38% PDB header:transferase Chain: A: PDB Molecule:malonyl coa-acyl carrier protein transacylase; PDBTitle: crystal structure of mcat from staphylococcus aureus Phyre2 PDB 2qj3 chain B Region: 2 - 309 Aligned: 301 Modelled: 306 Confidence: 100.0% Identity: 32% PDB header:transferase Chain: B: PDB Molecule:malonyl coa-acyl carrier protein transacylase; PDBTitle: mycobacterium tuberculosis fabd Phyre2 PDB 2cuy chain A Region: 5 - 308 Aligned: 299 Modelled: 304 Confidence: 100.0% Identity: 44% PDB header:transferase Chain: A: PDB Molecule:malonyl coa-[acyl carrier protein] transacylase; PDBTitle: crystal structure of malonyl coa-acyl carrier protein transacylase2 from thermus thermophilus hb8 Phyre2 PDB 2cdh chain 9 Region: 3 - 309 Aligned: 299 Modelled: 307 Confidence: 100.0% Identity: 36% PDB header:transferase Chain: 9: PDB Molecule:acetyl transferase; PDBTitle: architecture of the thermomyces lanuginosus fungal fatty2 acid synthase at 5 angstrom resolution. Phyre2 PDB 2h1y chain A Region: 3 - 309 Aligned: 300 Modelled: 307 Confidence: 100.0% Identity: 33% PDB header:transferase Chain: A: PDB Molecule:malonyl coenzyme a-acyl carrier protein transacylase; PDBTitle: crystal structure of malonyl-coa:acyl carrier protein transacylase2 (mcat) from helicobacter pylori Phyre2 PDB 3rgi chain A Region: 4 - 293 Aligned: 281 Modelled: 290 Confidence: 100.0% Identity: 40% PDB header:transferase Chain: A: PDB Molecule:disd protein; PDBTitle: trans-acting transferase from disorazole synthase Phyre2 PDB 2qo3 chain A Region: 2 - 296 Aligned: 288 Modelled: 295 Confidence: 100.0% Identity: 27% PDB header:transferase Chain: A: PDB Molecule:eryaii erythromycin polyketide synthase modules 3 and 4; PDBTitle: crystal structure of [ks3][at3] didomain from module 3 of 6-2 deoxyerthronolide b synthase Phyre2 PDB 2c2n chain A Region: 2 - 290 Aligned: 288 Modelled: 289 Confidence: 100.0% Identity: 34% PDB header:transferase Chain: A: PDB Molecule:malonyl coa-acyl carrier protein transacylase; PDBTitle: structure of human mitochondrial malonyltransferase Phyre2 PDB 3g87 chain A Region: 3 - 294 Aligned: 282 Modelled: 292 Confidence: 100.0% Identity: 37% PDB header:transferase Chain: A: PDB Molecule:malonyl coa-acyl carrier protein transacylase; PDBTitle: crystal structure of malonyl coa-acyl carrier protein transacylase2 from burkholderia pseudomallei using dried seaweed as nucleant or3 protease Phyre2 PDB 2hg4 chain A Region: 2 - 298 Aligned: 288 Modelled: 295 Confidence: 100.0% Identity: 27% PDB header:transferase Chain: A: PDB Molecule:6-deoxyerythronolide b synthase; PDBTitle: structure of the ketosynthase-acyltransferase didomain of module 52 from debs. Phyre2 PDB 3hhd chain C Region: 2 - 297 Aligned: 284 Modelled: 296 Confidence: 100.0% Identity: 21% PDB header:transferase, hydrolase Chain: C: PDB Molecule:fatty acid synthase; PDBTitle: structure of the human fatty acid synthase ks-mat didomain2 as a framework for inhibitor design. Phyre2 PDB 2jfk chain D Region: 2 - 298 Aligned: 285 Modelled: 297 Confidence: 100.0% Identity: 20% PDB header:transferase Chain: D: PDB Molecule:fatty acid synthase; PDBTitle: structure of the mat domain of human fas with malonyl-coa Phyre2 PDB 1mla chain A domain 1 Region: 3 - 307 Aligned: 235 Modelled: 235 Confidence: 100.0% Identity: 100% Fold: FabD/lysophospholipase-like Superfamily: FabD/lysophospholipase-like Family: FabD-like Phyre2 1 c2g2oA_ 2 c3eenA_ 3 c3im8A_ 4 c3ezoA_ 5 c3tqeA_ 6 c3qatB_ 7 c3ptwA_ 8 c3im9A_ 9 c2qj3B_ 10 c2cuyA_ 11 c2cdh9_ 12 c2h1yA_ 13 c3rgiA_ 14 c2qo3A_ 15 c2c2nA_ 16 c3g87A_ 17 c2hg4A_ 18 c3hhdC_ 19 c2jfkD_ 20 d1mlaa1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2g2oA_ 100.0 100 PDB header:transferase Chain: A: PDB Molecule:malonyl coa-acyl carrier protein transacylase; PDBTitle: structure of e.coli fabd complexed with sulfate 2 c3eenA_ 100.0 54 PDB header:transferase Chain: A: PDB Molecule:malonyl coa-acp transacylase; PDBTitle: crystal structure of malonyl-coa:acyl carrier protein transacylase2 (fabd), xoo0880, from xanthomonas oryzae pv. oryzae kacc10331 3 c3im8A_ 100.0 45 PDB header:transferase Chain: A: PDB Molecule:malonyl acyl carrier protein transacylase; PDBTitle: crystal structure of mcat from streptococcus pneumoniae 4 c3ezoA_ 100.0 55 PDB header:transferase Chain: A: PDB Molecule:malonyl coa-acyl carrier protein transacylase; PDBTitle: crystal structure of acyl-carrier-protein s-2 malonyltransferase from burkholderia pseudomallei 1710b 5 c3tqeA_ 100.0 54 PDB header:transferase Chain: A: PDB Molecule:malonyl-coa-[acyl-carrier-protein] transacylase; PDBTitle: structure of the malonyl coa-acyl carrier protein transacylase (fabd)2 from coxiella burnetii 6 c3qatB_ 100.0 43 PDB header:transferase Chain: B: PDB Molecule:malonyl coa-acyl carrier protein transacylase; PDBTitle: crystal structure of acyl-carrier-protein-s-malonyltransferase from2 bartonella henselae 7 c3ptwA_ 100.0 39 PDB header:transferase Chain: A: PDB Molecule:malonyl coa-acyl carrier protein transacylase; PDBTitle: crystal structure of malonyl coa-acyl carrier protein transacylase2 from clostridium perfringens atcc 13124 8 c3im9A_ 100.0 38 PDB header:transferase Chain: A: PDB Molecule:malonyl coa-acyl carrier protein transacylase; PDBTitle: crystal structure of mcat from staphylococcus aureus 9 c2qj3B_ 100.0 32 PDB header:transferase Chain: B: PDB Molecule:malonyl coa-acyl carrier protein transacylase; PDBTitle: mycobacterium tuberculosis fabd 10 c2cuyA_ 100.0 44 PDB header:transferase Chain: A: PDB Molecule:malonyl coa-[acyl carrier protein] transacylase; PDBTitle: crystal structure of malonyl coa-acyl carrier protein transacylase2 from thermus thermophilus hb8 11 c2cdh9_ 100.0 36 PDB header:transferase Chain: 9: PDB Molecule:acetyl transferase; PDBTitle: architecture of the thermomyces lanuginosus fungal fatty2 acid synthase at 5 angstrom resolution. 12 c2h1yA_ 100.0 33 PDB header:transferase Chain: A: PDB Molecule:malonyl coenzyme a-acyl carrier protein transacylase; PDBTitle: crystal structure of malonyl-coa:acyl carrier protein transacylase2 (mcat) from helicobacter pylori 13 c3rgiA_ 100.0 40 PDB header:transferase Chain: A: PDB Molecule:disd protein; PDBTitle: trans-acting transferase from disorazole synthase 14 c2qo3A_ 100.0 27 PDB header:transferase Chain: A: PDB Molecule:eryaii erythromycin polyketide synthase modules 3 and 4; PDBTitle: crystal structure of [ks3][at3] didomain from module 3 of 6-2 deoxyerthronolide b synthase 15 c2c2nA_ 100.0 34 PDB header:transferase Chain: A: PDB Molecule:malonyl coa-acyl carrier protein transacylase; PDBTitle: structure of human mitochondrial malonyltransferase 16 c3g87A_ 100.0 37 PDB header:transferase Chain: A: PDB Molecule:malonyl coa-acyl carrier protein transacylase; PDBTitle: crystal structure of malonyl coa-acyl carrier protein transacylase2 from burkholderia pseudomallei using dried seaweed as nucleant or3 protease 17 c2hg4A_ 100.0 27 PDB header:transferase Chain: A: PDB Molecule:6-deoxyerythronolide b synthase; PDBTitle: structure of the ketosynthase-acyltransferase didomain of module 52 from debs. 18 c3hhdC_ 100.0 21 PDB header:transferase, hydrolase Chain: C: PDB Molecule:fatty acid synthase; PDBTitle: structure of the human fatty acid synthase ks-mat didomain2 as a framework for inhibitor design. 19 c2jfkD_ 100.0 20 PDB header:transferase Chain: D: PDB Molecule:fatty acid synthase; PDBTitle: structure of the mat domain of human fas with malonyl-coa 20 d1mlaa1 100.0 100 Fold:FabD/lysophospholipase-like Superfamily:FabD/lysophospholipase-like Family:FabD-like 21 c2vz8B_ not modelled 100.0 22 PDB header:transferase Chain: B: PDB Molecule:fatty acid synthase; PDBTitle: crystal structure of mammalian fatty acid synthase 22 d1nm2a1 not modelled 100.0 41 Fold:FabD/lysophospholipase-like Superfamily:FabD/lysophospholipase-like Family:FabD-like 23 c2vkzH_ not modelled 100.0 24 PDB header:transferase Chain: H: PDB Molecule:fatty acid synthase subunit beta; PDBTitle: structure of the cerulenin-inhibited fungal fatty acid2 synthase type i multienzyme complex 24 c2uvaI_ not modelled 100.0 22 PDB header:transferase Chain: I: PDB Molecule:fatty acid synthase beta subunits; PDBTitle: crystal structure of fatty acid synthase from thermomyces2 lanuginosus at 3.1 angstrom resolution. this file contains3 the beta subunits of the fatty acid synthase. the entire4 crystal structure consists of one heterododecameric fatty5 acid synthase and is described in remark 400 25 d1mlaa2 not modelled 99.3 100 Fold:Ferredoxin-like Superfamily:Probable ACP-binding domain of malonyl-CoA ACP transacylase Family:Probable ACP-binding domain of malonyl-CoA ACP transacylase 26 d1nm2a2 not modelled 98.7 27 Fold:Ferredoxin-like Superfamily:Probable ACP-binding domain of malonyl-CoA ACP transacylase Family:Probable ACP-binding domain of malonyl-CoA ACP transacylase 27 c2uv9B_ not modelled 98.7 28 PDB header:transferase Chain: B: PDB Molecule:fatty acid synthase alpha subunits; PDBTitle: crystal structure of fatty acid synthase from thermomyces2 lanuginosus at 3.1 angstrom resolution. this file contains3 the alpha subunits of the fatty acid synthase. the entire4 crystal structure consists of one heterododecameric fatty5 acid synthase and is described in remark 400 28 c2vkzC_ not modelled 98.5 26 PDB header:transferase Chain: C: PDB Molecule:fatty acid synthase subunit alpha; PDBTitle: structure of the cerulenin-inhibited fungal fatty acid2 synthase type i multienzyme complex 29 c2uv8C_ not modelled 98.5 26 PDB header:transferase Chain: C: PDB Molecule:fatty acid synthase subunit alpha (fas2); PDBTitle: crystal structure of yeast fatty acid synthase with stalled2 acyl carrier protein at 3.1 angstrom resolution 30 c3iraA_ not modelled 83.7 20 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved protein; PDBTitle: the crystal structure of one domain of the conserved protein from2 methanosarcina mazei go1 31 c3i1iA_ not modelled 79.7 20 PDB header:transferase Chain: A: PDB Molecule:homoserine o-acetyltransferase; PDBTitle: x-ray crystal structure of homoserine o-acetyltransferase from2 bacillus anthracis 32 c3ds8A_ not modelled 78.4 24 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:lin2722 protein; PDBTitle: the crysatl structure of the gene lin2722 products from listeria2 innocua 33 d2vata1 not modelled 73.8 22 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:O-acetyltransferase 34 d2b61a1 not modelled 72.6 20 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:O-acetyltransferase 35 c1cr6A_ not modelled 71.7 21 PDB header:hydrolase Chain: A: PDB Molecule:epoxide hydrolase; PDBTitle: crystal structure of murine soluble epoxide hydrolase2 complexed with cpu inhibitor 36 d2pl5a1 not modelled 71.4 22 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:O-acetyltransferase 37 d1ex9a_ not modelled 71.1 23 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Bacterial lipase 38 c2vavL_ not modelled 70.2 20 PDB header:transferase Chain: L: PDB Molecule:acetyl-coa--deacetylcephalosporin c PDBTitle: crystal structure of deacetylcephalosporin c2 acetyltransferase (dac-soak) 39 c3lp5A_ not modelled 69.6 13 PDB header:hydrolase Chain: A: PDB Molecule:putative cell surface hydrolase; PDBTitle: the crystal structure of the putative cell surface hydrolase from2 lactobacillus plantarum wcfs1 40 d1xkta_ not modelled 67.8 23 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Thioesterase domain of polypeptide, polyketide and fatty acid synthases 41 c3bdvB_ not modelled 67.8 28 PDB header:hydrolase Chain: B: PDB Molecule:uncharacterized protein duf1234; PDBTitle: crystal structure of a putative yden-like hydrolase (eca3091) from2 pectobacterium atrosepticum scri1043 at 1.66 a resolution 42 c1qgeD_ not modelled 67.3 28 PDB header:hydrolase Chain: D: PDB Molecule:protein (triacylglycerol hydrolase); PDBTitle: new crystal form of pseudomonas glumae (formerly chromobacterium2 viscosum atcc 6918) lipase 43 c1mo2A_ not modelled 66.8 24 PDB header:transferase Chain: A: PDB Molecule:erythronolide synthase, modules 5 and 6; PDBTitle: thioesterase domain from 6-deoxyerythronolide synthase2 (debs te), ph 8.5 44 d1mo2a_ not modelled 66.8 24 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Thioesterase domain of polypeptide, polyketide and fatty acid synthases 45 c2q0xA_ not modelled 66.7 10 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: alpha/beta hydrolase fold protein of unknown function 46 c3lcrA_ not modelled 64.5 32 PDB header:hydrolase Chain: A: PDB Molecule:tautomycetin biosynthetic pks; PDBTitle: thioesterase from tautomycetin biosynthhetic pathway 47 d1ispa_ not modelled 64.4 23 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Bacterial lipase 48 d1zkda1 not modelled 63.3 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:RPA4359-like 49 c3l80A_ not modelled 62.5 17 PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein smu.1393c; PDBTitle: crystal structure of smu.1393c from streptococcus mutans ua159 50 c3giwA_ not modelled 61.9 16 PDB header:unknown function Chain: A: PDB Molecule:protein of unknown function duf574; PDBTitle: crystal structure of a duf574 family protein (sav_2177) from2 streptomyces avermitilis ma-4680 at 1.45 a resolution 51 c2h7xA_ not modelled 61.0 29 PDB header:hydrolase Chain: A: PDB Molecule:type i polyketide synthase pikaiv; PDBTitle: pikromycin thioesterase adduct with reduced triketide2 affinity label 52 d1lpbb2 not modelled 59.9 21 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Pancreatic lipase, N-terminal domain 53 c2zyiB_ not modelled 58.7 20 PDB header:hydrolase Chain: B: PDB Molecule:lipase, putative; PDBTitle: a. fulgidus lipase with fatty acid fragment and calcium 54 c3qmwD_ not modelled 58.0 20 PDB header:hydrolase Chain: D: PDB Molecule:thioesterase; PDBTitle: redj with peg molecule bound in the active site 55 d1bu8a2 not modelled 57.2 30 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Pancreatic lipase, N-terminal domain 56 d4lipd_ not modelled 56.7 28 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Bacterial lipase 57 c2y6vB_ not modelled 56.4 42 PDB header:hydrolase Chain: B: PDB Molecule:peroxisomal membrane protein lpx1; PDBTitle: peroxisomal alpha-beta-hydrolase lpx1 (yor084w) from2 saccharomyces cerevisiae (crystal form i) 58 c3fleB_ not modelled 55.9 23 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:se_1780 protein; PDBTitle: se_1780 protein of unknown function from staphylococcus epidermidis. 59 d1k8qa_ not modelled 55.1 19 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Gastric lipase 60 c2qs9A_ not modelled 54.6 23 PDB header:structural protein Chain: A: PDB Molecule:retinoblastoma-binding protein 9; PDBTitle: crystal structure of the human retinoblastoma-binding2 protein 9 (rbbp-9). nesg target hr2978 61 c3flaB_ not modelled 53.9 34 PDB header:hydrolase Chain: B: PDB Molecule:rifr; PDBTitle: rifr - type ii thioesterase from rifamycin nrps/pks biosynthetic2 pathway - form 1 62 c2qmqA_ not modelled 53.6 17 PDB header:signaling protein Chain: A: PDB Molecule:protein ndrg2; PDBTitle: crystal structure of a n-myc downstream regulated 2 protein (ndrg2,2 syld, ndr2, ai182517, au040374) from mus musculus at 1.70 a3 resolution 63 d2h7xa1 not modelled 53.6 38 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Thioesterase domain of polypeptide, polyketide and fatty acid synthases 64 d1hlga_ not modelled 52.6 20 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Gastric lipase 65 c1i4wA_ not modelled 52.1 12 PDB header:transcription Chain: A: PDB Molecule:mitochondrial replication protein mtf1; PDBTitle: the crystal structure of the transcription factor sc-mttfb2 offers intriguing insights into mitochondrial transcription 66 d1i4wa_ not modelled 52.1 12 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:rRNA adenine dimethylase-like 67 d1cvla_ not modelled 52.0 28 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Bacterial lipase 68 c2cbgA_ not modelled 50.5 17 PDB header:hydrolase Chain: A: PDB Molecule:fengycin synthetase; PDBTitle: crystal structure of the pmsf-inhibited thioesterase domain2 of the fengycin biosynthesis cluster 69 d1uxoa_ not modelled 49.7 26 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:YdeN-like 70 d1rp1a2 not modelled 49.6 27 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Pancreatic lipase, N-terminal domain 71 c3qvmA_ not modelled 48.7 10 PDB header:hydrolase Chain: A: PDB Molecule:olei00960; PDBTitle: the structure of olei00960, a hydrolase from oleispira antarctica 72 c1pjaA_ not modelled 47.8 6 PDB header:hydrolase Chain: A: PDB Molecule:palmitoyl-protein thioesterase 2 precursor; PDBTitle: the crystal structure of palmitoyl protein thioesterase-2 reveals the2 basis for divergent substrate specificities of the two lysosomal3 thioesterases (ppt1 and ppt2) 73 d1pjaa_ not modelled 47.8 6 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Thioesterases 74 d1jmkc_ not modelled 46.8 23 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Thioesterase domain of polypeptide, polyketide and fatty acid synthases 75 c1gplA_ not modelled 46.5 29 PDB header:serine esterase Chain: A: PDB Molecule:rp2 lipase; PDBTitle: rp2 lipase 76 c2rauA_ not modelled 45.2 23 PDB header:hydrolase Chain: A: PDB Molecule:putative esterase; PDBTitle: crystal structure of a putative lipase (np_343859.1) from sulfolobus2 solfataricus at 1.85 a resolution 77 d1etha2 not modelled 45.1 32 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Pancreatic lipase, N-terminal domain 78 d1tcaa_ not modelled 45.0 18 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Fungal lipases 79 c2qe6B_ not modelled 44.9 12 PDB header:transferase Chain: B: PDB Molecule:uncharacterized protein tfu_2867; PDBTitle: crystal structure of a putative methyltransferase (tfu_2867) from2 thermobifida fusca yx at 1.95 a resolution 80 c2qjwA_ not modelled 44.7 32 PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized protein xcc1541; PDBTitle: crystal structure of a putative hydrolase of the alpha/beta2 superfamily (xcc1541) from xanthomonas campestris pv. campestris at3 1.35 a resolution 81 d2dsta1 not modelled 42.5 7 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:TTHA1544-like 82 c1hplB_ not modelled 41.9 32 PDB header:hydrolase(carboxylic esterase) Chain: B: PDB Molecule:lipase; PDBTitle: horse pancreatic lipase. the crystal structure at 2.32 angstroms resolution 83 d1gpla2 not modelled 39.3 23 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Pancreatic lipase, N-terminal domain 84 c3h04A_ not modelled 39.1 25 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: the crystal structure of the protein with unknown function from2 staphylococcus aureus subsp. aureus mu50 85 d1hpla2 not modelled 38.5 27 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Pancreatic lipase, N-terminal domain 86 c3ilsA_ not modelled 35.7 19 PDB header:hydrolase Chain: A: PDB Molecule:aflatoxin biosynthesis polyketide synthase; PDBTitle: the thioesterase domain from pksa 87 d1r88a_ not modelled 34.8 30 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Mycobacterial antigens 88 c2vtvA_ not modelled 32.7 31 PDB header:hydrolase Chain: A: PDB Molecule:phb depolymerase phaz7; PDBTitle: phaz7 depolymerase from paucimonas lemoignei 89 d1uwca_ not modelled 32.4 28 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Fungal lipases 90 c2pvsB_ not modelled 29.7 23 PDB header:hydrolase Chain: B: PDB Molecule:pancreatic lipase-related protein 2; PDBTitle: structure of human pancreatic lipase related protein 22 mutant n336q 91 d1dqza_ not modelled 29.1 30 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Mycobacterial antigens 92 d1ei9a_ not modelled 28.8 11 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Thioesterases 93 d1sfra_ not modelled 27.9 30 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Mycobacterial antigens 94 c2veoA_ not modelled 27.7 16 PDB header:hydrolase Chain: A: PDB Molecule:lipase a; PDBTitle: x-ray structure of candida antarctica lipase a in its2 closed state. 95 c1rp1A_ not modelled 27.5 21 PDB header:hydrolase Chain: A: PDB Molecule:pancreatic lipase related protein 1; PDBTitle: dog pancreatic lipase related protein 1 96 c3og9A_ not modelled 27.5 16 PDB header:hydrolase Chain: A: PDB Molecule:protein yahd a copper inducible hydrolase; PDBTitle: structure of yahd with malic acid 97 c2pplA_ not modelled 27.4 23 PDB header:hydrolase Chain: A: PDB Molecule:pancreatic lipase-related protein 1; PDBTitle: human pancreatic lipase-related protein 1 98 c3uzuA_ not modelled 27.1 24 PDB header:transferase Chain: A: PDB Molecule:ribosomal rna small subunit methyltransferase a; PDBTitle: the structure of the ribosomal rna small subunit methyltransferase a2 from burkholderia pseudomallei 99 c2jbwB_ not modelled 26.5 29 PDB header:hydrolase Chain: B: PDB Molecule:2,6-dihydroxy-pseudo-oxynicotine hydrolase; PDBTitle: crystal structure of the 2,6-dihydroxy-pseudo-oxynicotine2 hydrolase. 100 d2jbwa1 not modelled 25.9 29 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:2,6-dihydropseudooxynicotine hydrolase-like 101 c2r11D_ not modelled 25.8 22 PDB header:hydrolase Chain: D: PDB Molecule:carboxylesterase np; PDBTitle: crystal structure of putative hydrolase (2632844) from2 bacillus subtilis at 1.96 a resolution 102 d3b5ea1 not modelled 25.7 19 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carboxylesterase/thioesterase 1 103 d3tgla_ not modelled 25.5 34 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Fungal lipases 104 c3o0dF_ not modelled 25.3 25 PDB header:hydrolase Chain: F: PDB Molecule:triacylglycerol lipase; PDBTitle: crystal structure of lip2 lipase from yarrowia lipolytica at 1.7 a2 resolution 105 c3d59B_ not modelled 25.2 25 PDB header:hydrolase Chain: B: PDB Molecule:platelet-activating factor acetylhydrolase; PDBTitle: crystal structure of human plasma platelet activating2 factor acetylhydrolase 106 c2ecfA_ not modelled 25.0 27 PDB header:hydrolase Chain: A: PDB Molecule:dipeptidyl peptidase iv; PDBTitle: crystal structure of dipeptidyl aminopeptidase iv from2 stenotrophomonas maltophilia 107 c3fnbB_ not modelled 24.2 19 PDB header:hydrolase Chain: B: PDB Molecule:acylaminoacyl peptidase smu_737; PDBTitle: crystal structure of acylaminoacyl peptidase smu_737 from2 streptococcus mutans ua159 108 c2fx5A_ not modelled 23.7 24 PDB header:hydrolase Chain: A: PDB Molecule:lipase; PDBTitle: pseudomonas mendocina lipase 109 c3fuxB_ not modelled 22.8 19 PDB header:transferase Chain: B: PDB Molecule:dimethyladenosine transferase; PDBTitle: t. thermophilus 16s rrna a1518 and a1519 methyltransferase (ksga) in2 complex with 5'-methylthioadenosine in space group p212121 110 d1jqna_ not modelled 21.7 16 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate carboxylase 111 c2hu7A_ not modelled 21.3 24 PDB header:hydrolase Chain: A: PDB Molecule:acylamino-acid-releasing enzyme; PDBTitle: binding of inhibitors by acylaminoacyl peptidase 112 c3g7nA_ not modelled 21.1 16 PDB header:hydrolase Chain: A: PDB Molecule:lipase; PDBTitle: crystal structure of a triacylglycerol lipase from2 penicillium expansum at 1.3 113 d3c8da2 not modelled 21.0 30 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carboxylesterase 114 c3grrA_ not modelled 20.6 19 PDB header:transferase Chain: A: PDB Molecule:dimethyladenosine transferase; PDBTitle: crystal structure of the complex between s-adenosyl homocysteine and2 methanocaldococcus jannaschi dim1. 115 c3fydA_ not modelled 20.6 19 PDB header:transferase Chain: A: PDB Molecule:probable dimethyladenosine transferase; PDBTitle: crystal structure of dim1 from the thermophilic archeon,2 methanocaldococcus jannaschi 116 d1ku0a_ not modelled 20.5 19 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Bacterial lipase 117 c3azqA_ not modelled 20.5 18 PDB header:hydrolase Chain: A: PDB Molecule:aminopeptidase; PDBTitle: crystal structure of puromycin hydrolase s511a mutant complexed with2 pgg 118 d1tiaa_ not modelled 20.3 25 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Fungal lipases 119 d1tiba_ not modelled 20.1 17 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Fungal lipases

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0