Phyre 2 Results for P75711

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Email | l.a.kelley@imperial.ac.uk
Description | P75711
Date | Thu Jan 5 12:13:19 GMT 2012
Unique Job ID | 64c8785847c8e774

Summary |

Top model
Image coloured by rainbow N → C terminus
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Model (left) based on template c2k4jA_
Top template information
PDB header:transcription Chain: A: PDB Molecule:putative transcriptional regulator; PDBTitle: arsr dna binding domain
Confidence and coverage
Confidence: | 48.2% | Coverage: | 68%
63 residues ( 68% of your sequence) have been modelled with 48.2% confidence by the single highest scoring template.
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3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | N | R | P | A | I | L | K | K | K | A | A | K | D | V | A | S | V | L | K | I | I | F | L | F | Y | L | F | L | I | A | R | L | K | Q | R | Y | S | I | R | E | I | K | R | D | L | W | N | I | R | E | N | Y | S | S | N | A | A | I | A
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | .
Sequence |  | K | I | Y | C | R | K | R | K | A | S | G | P | G | K | H | L | T | I | L | P | Y | G | W | V | R | F | I | T | F | P | I | M
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| c2k4jA_ |

### PDB 2k4j chain A

Region: 23 - 85
Aligned: 63
Modelled: 63
Confidence: 48.2%
Identity: 16%
PDB header:transcription
Chain: A: PDB Molecule:putative transcriptional regulator;
PDBTitle: arsr dna binding domain

Phyre2
2 |
| d1opca_ |

### PDB 1opc chain A

Region: 23 - 85
Aligned: 63
Modelled: 63
Confidence: 35.8%
Identity: 14%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: C-terminal effector domain of the bipartite response regulators
Family: PhoB-like

Phyre2
3 |
| c2v1yA_ |

### PDB 2v1y chain A

Region: 38 - 54
Aligned: 17
Modelled: 17
Confidence: 33.6%
Identity: 24%
PDB header:transferase
Chain: A: PDB Molecule:phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic
PDBTitle: structure of a phosphoinositide 3-kinase alpha adaptor-2 binding domain (abd) in a complex with the ish2 domain3 from p85 alpha

Phyre2
4 |
| d1gxqa_ |

### PDB 1gxq chain A

Region: 23 - 85
Aligned: 63
Modelled: 63
Confidence: 31.1%
Identity: 14%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: C-terminal effector domain of the bipartite response regulators
Family: PhoB-like

Phyre2
5 |
| c3q9vB_ |

### PDB 3q9v chain B

Region: 23 - 85
Aligned: 63
Modelled: 63
Confidence: 31.1%
Identity: 25%
PDB header:dna binding protein
Chain: B: PDB Molecule:dna-binding response regulator;
PDBTitle: crystal structure of rra c-terminal domain(123-221) from deinococcus2 radiodurans

Phyre2
6 |
| c2hqnA_ |

### PDB 2hqn chain A

Region: 23 - 85
Aligned: 63
Modelled: 63
Confidence: 29.5%
Identity: 19%
PDB header:signaling protein
Chain: A: PDB Molecule:putative transcriptional regulator;
PDBTitle: structure of a atypical orphan response regulator protein revealed a2 new phosphorylation-independent regulatory mechanism

Phyre2
7 |
| c2hwvA_ |

### PDB 2hwv chain A

Region: 23 - 75
Aligned: 53
Modelled: 53
Confidence: 27.1%
Identity: 11%
PDB header:transcription
Chain: A: PDB Molecule:dna-binding response regulator vicr;
PDBTitle: crystal structure of an essential response regulator dna binding2 domain, vicrc in enterococcus faecalis, a member of the yycf3 subfamily.

Phyre2
8 |
| c2kq0A_ |

### PDB 2kq0 chain A

Region: 78 - 88
Aligned: 11
Modelled: 11
Confidence: 25.2%
Identity: 36%
PDB header:ligase
Chain: A: PDB Molecule:e3 ubiquitin-protein ligase nedd4;
PDBTitle: human nedd4 3rd ww domain complex with ebola zaire virus matrix2 protein vp40 derived peptide ilptappeymea

Phyre2
9 |
| c2vxzA_ |

### PDB 2vxz chain A

Region: 39 - 53
Aligned: 15
Modelled: 15
Confidence: 14.9%
Identity: 7%
PDB header:viral protein
Chain: A: PDB Molecule:pyrsv_gp04;
PDBTitle: crystal structure of hypothetical protein pyrsv_gp04 from2 pyrobaculum spherical virus

Phyre2
10 |
| c3q9sA_ |

### PDB 3q9s chain A

Region: 23 - 75
Aligned: 53
Modelled: 53
Confidence: 13.2%
Identity: 23%
PDB header:dna binding protein
Chain: A: PDB Molecule:dna-binding response regulator;
PDBTitle: crystal structure of rra(1-215) from deinococcus radiodurans

Phyre2
11 |
| c2j7uA_ |

### PDB 2j7u chain A

Region: 24 - 88
Aligned: 65
Modelled: 65
Confidence: 12.7%
Identity: 28%
PDB header:viral protein
Chain: A: PDB Molecule:rna dependent rna polymerase;
PDBTitle: dengue virus ns5 rna dependent rna polymerase domain

Phyre2
12 |
| d2f21a1 |

### PDB 2f21 chain A domain 1

Region: 79 - 88
Aligned: 10
Modelled: 10
Confidence: 12.7%
Identity: 40%
Fold: WW domain-like
Superfamily: WW domain
Family: WW domain

Phyre2
13 |
| c2kykA_ |

### PDB 2kyk chain A

Region: 73 - 88
Aligned: 16
Modelled: 16
Confidence: 11.4%
Identity: 38%
PDB header:ligase
Chain: A: PDB Molecule:e3 ubiquitin-protein ligase itchy homolog;
PDBTitle: the sandwich region between two lmp2a py motif regulates the2 interaction between aip4ww2domain and py motif

Phyre2
14 |
| c2zxjB_ |

### PDB 2zxj chain B

Region: 20 - 85
Aligned: 66
Modelled: 66
Confidence: 10.4%
Identity: 12%
PDB header:transcription
Chain: B: PDB Molecule:transcriptional regulatory protein walr;
PDBTitle: crystal structure of yycf dna-binding domain from staphylococcus2 aureus

Phyre2
15 |
| c2lazA_ |

### PDB 2laz chain A

Region: 79 - 88
Aligned: 10
Modelled: 10
Confidence: 10.1%
Identity: 40%
PDB header:signaling protein/transcription
Chain: A: PDB Molecule:e3 ubiquitin-protein ligase smurf1;
PDBTitle: structure of the first ww domain of human smurf1 in complex with a2 mono-phosphorylated human smad1 derived peptide

Phyre2
16 |
| c1wmvA_ |

### PDB 1wmv chain A

Region: 79 - 88
Aligned: 10
Modelled: 10
Confidence: 9.9%
Identity: 50%
PDB header:oxidoreductase, apoptosis
Chain: A: PDB Molecule:ww domain containing oxidoreductase;
PDBTitle: solution structure of the second ww domain of wwox

Phyre2
17 |
| c3ml6D_ |

### PDB 3ml6 chain D

Region: 80 - 88
Aligned: 9
Modelled: 9
Confidence: 9.8%
Identity: 44%
PDB header:protein transport
Chain: D: PDB Molecule:chimeric complex between protein dishevlled2 homolog dvl-2
PDBTitle: a complex between dishevlled2 and clathrin adaptor ap-2

Phyre2
18 |
| c2jzyA_ |

### PDB 2jzy chain A

Region: 23 - 78
Aligned: 56
Modelled: 56
Confidence: 9.7%
Identity: 14%
PDB header:transcription
Chain: A: PDB Molecule:transcriptional regulatory protein pcor;
PDBTitle: solution structure of c-terminal effector domain of2 putative two-component-system response regulator involved3 in copper resistance from klebsiella pneumoniae

Phyre2
19 |
| c2zajA_ |

### PDB 2zaj chain A

Region: 79 - 88
Aligned: 10
Modelled: 10
Confidence: 9.7%
Identity: 40%
PDB header:protein binding
Chain: A: PDB Molecule:membrane-associated guanylate kinase, ww and pdz
PDBTitle: solution structure of the short-isoform of the second ww2 domain from the human membrane-associated guanylate kinase,3 ww and pdz domain-containing protein 1 (magi-1)

Phyre2
20 |
| c1k6nH_ |

### PDB 1k6n chain H

Region: 14 - 44
Aligned: 27
Modelled: 31
Confidence: 9.6%
Identity: 37%
PDB header:photosynthesis
Chain: H: PDB Molecule:photosynthetic reaction center h subunit;
PDBTitle: e(l212)a,d(l213)a double mutant structure of photosynthetic reaction2 center from rhodobacter sphaeroides

Phyre2
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61 |
62 |

Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | c2k4jA_ |
|  | 48.2 | 16 | PDB header:transcription Chain: A: PDB Molecule:putative transcriptional regulator; PDBTitle: arsr dna binding domain
2 | d1opca_ |
|  | 35.8 | 14 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:C-terminal effector domain of the bipartite response regulators Family:PhoB-like
3 | c2v1yA_ |
|  | 33.6 | 24 | PDB header:transferase Chain: A: PDB Molecule:phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic PDBTitle: structure of a phosphoinositide 3-kinase alpha adaptor-2 binding domain (abd) in a complex with the ish2 domain3 from p85 alpha
4 | d1gxqa_ |
|  | 31.1 | 14 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:C-terminal effector domain of the bipartite response regulators Family:PhoB-like
5 | c3q9vB_ |
|  | 31.1 | 25 | PDB header:dna binding protein Chain: B: PDB Molecule:dna-binding response regulator; PDBTitle: crystal structure of rra c-terminal domain(123-221) from deinococcus2 radiodurans
6 | c2hqnA_ |
|  | 29.5 | 19 | PDB header:signaling protein Chain: A: PDB Molecule:putative transcriptional regulator; PDBTitle: structure of a atypical orphan response regulator protein revealed a2 new phosphorylation-independent regulatory mechanism
7 | c2hwvA_ |
|  | 27.1 | 11 | PDB header:transcription Chain: A: PDB Molecule:dna-binding response regulator vicr; PDBTitle: crystal structure of an essential response regulator dna binding2 domain, vicrc in enterococcus faecalis, a member of the yycf3 subfamily.
8 | c2kq0A_ |
|  | 25.2 | 36 | PDB header:ligase Chain: A: PDB Molecule:e3 ubiquitin-protein ligase nedd4; PDBTitle: human nedd4 3rd ww domain complex with ebola zaire virus matrix2 protein vp40 derived peptide ilptappeymea
9 | c2vxzA_ |
|  | 14.9 | 7 | PDB header:viral protein Chain: A: PDB Molecule:pyrsv_gp04; PDBTitle: crystal structure of hypothetical protein pyrsv_gp04 from2 pyrobaculum spherical virus
10 | c3q9sA_ |
|  | 13.2 | 23 | PDB header:dna binding protein Chain: A: PDB Molecule:dna-binding response regulator; PDBTitle: crystal structure of rra(1-215) from deinococcus radiodurans
11 | c2j7uA_ |
|  | 12.7 | 28 | PDB header:viral protein Chain: A: PDB Molecule:rna dependent rna polymerase; PDBTitle: dengue virus ns5 rna dependent rna polymerase domain
12 | d2f21a1 |
|  | 12.7 | 40 | Fold:WW domain-like Superfamily:WW domain Family:WW domain
13 | c2kykA_ |
|  | 11.4 | 38 | PDB header:ligase Chain: A: PDB Molecule:e3 ubiquitin-protein ligase itchy homolog; PDBTitle: the sandwich region between two lmp2a py motif regulates the2 interaction between aip4ww2domain and py motif
14 | c2zxjB_ |
|  | 10.4 | 12 | PDB header:transcription Chain: B: PDB Molecule:transcriptional regulatory protein walr; PDBTitle: crystal structure of yycf dna-binding domain from staphylococcus2 aureus
15 | c2lazA_ |
|  | 10.1 | 40 | PDB header:signaling protein/transcription Chain: A: PDB Molecule:e3 ubiquitin-protein ligase smurf1; PDBTitle: structure of the first ww domain of human smurf1 in complex with a2 mono-phosphorylated human smad1 derived peptide
16 | c1wmvA_ |
|  | 9.9 | 50 | PDB header:oxidoreductase, apoptosis Chain: A: PDB Molecule:ww domain containing oxidoreductase; PDBTitle: solution structure of the second ww domain of wwox
17 | c3ml6D_ |
|  | 9.8 | 44 | PDB header:protein transport Chain: D: PDB Molecule:chimeric complex between protein dishevlled2 homolog dvl-2 PDBTitle: a complex between dishevlled2 and clathrin adaptor ap-2
18 | c2jzyA_ |
|  | 9.7 | 14 | PDB header:transcription Chain: A: PDB Molecule:transcriptional regulatory protein pcor; PDBTitle: solution structure of c-terminal effector domain of2 putative two-component-system response regulator involved3 in copper resistance from klebsiella pneumoniae
19 | c2zajA_ |
|  | 9.7 | 40 | PDB header:protein binding Chain: A: PDB Molecule:membrane-associated guanylate kinase, ww and pdz PDBTitle: solution structure of the short-isoform of the second ww2 domain from the human membrane-associated guanylate kinase,3 ww and pdz domain-containing protein 1 (magi-1)
20 | c1k6nH_ |
|  | 9.6 | 37 | PDB header:photosynthesis Chain: H: PDB Molecule:photosynthetic reaction center h subunit; PDBTitle: e(l212)a,d(l213)a double mutant structure of photosynthetic reaction2 center from rhodobacter sphaeroides
21 | c2lb0A_ |
| not modelled | 9.0 | 40 | PDB header:signaling protein/transcription Chain: A: PDB Molecule:e3 ubiquitin-protein ligase smurf1; PDBTitle: structure of the first ww domain of human smurf1 in complex with a di-2 phosphorylated human smad1 derived peptide
22 | c2pmuD_ |
| not modelled | 8.9 | 18 | PDB header:transcription regulation Chain: D: PDB Molecule:response regulator phop; PDBTitle: crystal structure of the dna-binding domain of phop
23 | d1tk7a2 |
| not modelled | 8.8 | 50 | Fold:WW domain-like Superfamily:WW domain Family:WW domain
24 | c2dmvA_ |
| not modelled | 8.8 | 40 | PDB header:ligase Chain: A: PDB Molecule:itchy homolog e3 ubiquitin protein ligase; PDBTitle: solution structure of the second ww domain of itchy homolog2 e3 ubiquitin protein ligase (itch)
25 | c3l81A_ |
| not modelled | 8.7 | 44 | PDB header:transport protein Chain: A: PDB Molecule:ap-4 complex subunit mu-1; PDBTitle: crystal structure of adaptor protein complex 4 (ap-4) mu4 subunit c-2 terminal domain, in complex with a sorting peptide from the amyloid3 precursor protein (app)
26 | d1wfxa_ |
| not modelled | 8.4 | 18 | Fold:ADP-ribosylation Superfamily:ADP-ribosylation Family:Tpt1/KptA
27 | c2ysbA_ |
| not modelled | 8.3 | 50 | PDB header:protein binding Chain: A: PDB Molecule:salvador homolog 1 protein; PDBTitle: solution structure of the first ww domain from the mouse2 salvador homolog 1 protein (sav1)
28 | c1bw8A_ |
| not modelled | 8.3 | 44 | PDB header:peptide binding protein Chain: A: PDB Molecule:protein (mu2 adaptin subunit); PDBTitle: mu2 adaptin subunit (ap50) of ap2 adaptor (second domain),2 complexed with egfr internalization peptide fyralm
29 | c2lawA_ |
| not modelled | 8.0 | 50 | PDB header:signaling protein/transcription Chain: A: PDB Molecule:yorkie homolog; PDBTitle: structure of the second ww domain from human yap in complex with a2 human smad1 derived peptide
30 | c1eysH_ |
| not modelled | 7.9 | 41 | PDB header:electron transport Chain: H: PDB Molecule:photosynthetic reaction center; PDBTitle: crystal structure of photosynthetic reaction center from a2 thermophilic bacterium, thermochromatium tepidum
31 | d1i8gb_ |
| not modelled | 7.8 | 40 | Fold:WW domain-like Superfamily:WW domain Family:WW domain
32 | c2jmfA_ |
| not modelled | 7.7 | 50 | PDB header:ligase/signaling protein Chain: A: PDB Molecule:e3 ubiquitin-protein ligase suppressor of deltex; PDBTitle: solution structure of the su(dx) ww4- notch py peptide2 complex
33 | d2pr9a1 |
| not modelled | 7.6 | 44 | Fold:Common fold of diphtheria toxin/transcription factors/cytochrome f Superfamily:Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor Family:Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
34 | c1ymzA_ |
| not modelled | 7.5 | 50 | PDB header:unknown function Chain: A: PDB Molecule:cc45; PDBTitle: cc45, an artificial ww domain designed using statistical2 coupling analysis
35 | c1wr7A_ |
| not modelled | 7.3 | 50 | PDB header:ligase Chain: A: PDB Molecule:nedd4-2; PDBTitle: solution structure of the third ww domain of nedd4-2
36 | c2l4jA_ |
| not modelled | 7.2 | 60 | PDB header:transcription Chain: A: PDB Molecule:yes-associated protein 2 (yap2); PDBTitle: yap ww2
37 | c2yshA_ |
| not modelled | 7.2 | 40 | PDB header:protein binding Chain: A: PDB Molecule:growth-arrest-specific protein 7; PDBTitle: solution structure of the ww domain from the human growth-2 arrest-specific protein 7, gas-7
38 | d1ys7a1 |
| not modelled | 7.2 | 16 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:C-terminal effector domain of the bipartite response regulators Family:PhoB-like
39 | c2gwwB_ |
| not modelled | 7.1 | 50 | PDB header:cell adhesion, structural protein Chain: B: PDB Molecule:ipaa; PDBTitle: human vinculin (head domain, vh1, residues 1-258) in2 complex with shigella's ipaa vinculin binding site3 (residues 602-633)
40 | c3ll6B_ |
| not modelled | 7.1 | 30 | PDB header:transferase Chain: B: PDB Molecule:cyclin g-associated kinase; PDBTitle: crystal structure of the human cyclin g associated kinase (gak)
41 | d1nmva1 |
| not modelled | 7.0 | 40 | Fold:WW domain-like Superfamily:WW domain Family:WW domain
42 | d2jmfa1 |
| not modelled | 6.8 | 50 | Fold:WW domain-like Superfamily:WW domain Family:WW domain
43 | d1f8ab1 |
| not modelled | 6.7 | 40 | Fold:WW domain-like Superfamily:WW domain Family:WW domain
44 | c1wr4A_ |
| not modelled | 6.7 | 40 | PDB header:ligase Chain: A: PDB Molecule:ubiquitin-protein ligase nedd4-2; PDBTitle: solution structure of the second ww domain of nedd4-2
45 | c3ogfA_ |
| not modelled | 6.6 | 43 | PDB header:de novo protein Chain: A: PDB Molecule:de novo designed dimeric trefoil-fold sub-domain which PDBTitle: crystal structure of difoil-4p homo-trimer: de novo designed dimeric2 trefoil-fold sub-domain which forms homo-trimer assembly
46 | c1e0mA_ |
| not modelled | 6.5 | 50 | PDB header:de novo protein Chain: A: PDB Molecule:wwprototype; PDBTitle: prototype ww domain
47 | c2ez5W_ |
| not modelled | 6.5 | 30 | PDB header:signalling protein,ligase Chain: W: PDB Molecule:e3 ubiquitin-protein ligase nedd4; PDBTitle: solution structure of the dnedd4 ww3* domain- comm lpsy2 peptide complex
48 | c1w63P_ |
| not modelled | 6.3 | 56 | PDB header:endocytosis Chain: P: PDB Molecule:adaptor-related protein complex 1, mu 1 subunit; PDBTitle: ap1 clathrin adaptor core
49 | d1tk7a1 |
| not modelled | 6.2 | 50 | Fold:WW domain-like Superfamily:WW domain Family:WW domain
50 | c1yiuA_ |
| not modelled | 6.2 | 40 | PDB header:ligase Chain: A: PDB Molecule:itchy e3 ubiquitin protein ligase; PDBTitle: itch e3 ubiquitin ligase ww3 domain
51 | c2oqrA_ |
| not modelled | 6.2 | 8 | PDB header:transcription,signaling protein Chain: A: PDB Molecule:sensory transduction protein regx3; PDBTitle: the structure of the response regulator regx3 from mycobacterium2 tuberculosis
52 | d1iqoa_ |
| not modelled | 6.0 | 21 | Fold:Hypothetical protein MTH1880 Superfamily:Hypothetical protein MTH1880 Family:Hypothetical protein MTH1880
53 | c2dwvB_ |
| not modelled | 5.9 | 50 | PDB header:protein binding Chain: B: PDB Molecule:salvador homolog 1 protein; PDBTitle: solution structure of the second ww domain from mouse2 salvador homolog 1 protein (mww45)
54 | d1k9ra_ |
| not modelled | 5.9 | 50 | Fold:WW domain-like Superfamily:WW domain Family:WW domain
55 | c2ysgA_ |
| not modelled | 5.7 | 60 | PDB header:protein binding Chain: A: PDB Molecule:syntaxin-binding protein 4; PDBTitle: solution structure of the ww domain from the human syntaxin-2 binding protein 4
56 | d1flca2 |
| not modelled | 5.7 | 57 | Fold:Flavodoxin-like Superfamily:SGNH hydrolase Family:Esterase domain of haemagglutinin-esterase-fusion glycoprotein HEF1
57 | c2ysdA_ |
| not modelled | 5.7 | 33 | PDB header:protein binding Chain: A: PDB Molecule:membrane-associated guanylate kinase, ww and pdz PDBTitle: solution structure of the first ww domain from the human2 membrane-associated guanylate kinase, ww and pdz domain-3 containing protein 1. magi-1
58 | c2ysfA_ |
| not modelled | 5.4 | 50 | PDB header:protein binding Chain: A: PDB Molecule:e3 ubiquitin-protein ligase itchy homolog; PDBTitle: solution structure of the fourth ww domain from the human2 e3 ubiquitin-protein ligase itchy homolog, itch
59 | c3ol0C_ |
| not modelled | 5.3 | 46 | PDB header:de novo protein Chain: C: PDB Molecule:de novo designed monomer trefoil-fold sub-domain which PDBTitle: crystal structure of monofoil-4p homo-trimer: de novo designed monomer2 trefoil-fold sub-domain which forms homo-trimer assembly
60 | d2csba2 |
| not modelled | 5.3 | 36 | Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Topoisomerase V repeat domain
61 | c2jkrM_ |
| not modelled | 5.2 | 44 | PDB header:endocytosis Chain: M: PDB Molecule:ap-2 complex subunit mu-1; PDBTitle: ap2 clathrin adaptor core with dileucine peptide rm(2 phosphos)qikrllse
62 | c2ftcK_ |
| not modelled | 5.2 | 0 | PDB header:ribosome Chain: K: PDB Molecule:39s ribosomal protein l19, mitochondrial; PDBTitle: structural model for the large subunit of the mammalian mitochondrial2 ribosome

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0