Phyre 2 Results for P0AE18

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Email | l.a.kelley@imperial.ac.uk
Description | P0AE18
Date | Thu Jan 5 11:22:16 GMT 2012
Unique Job ID | 6373fe028fd6d4af

Summary |

Top model
Image coloured by rainbow N → C terminus
| Close Jmol

Model (left) based on template d2gg2a1
Top template information
Fold:Creatinase/aminopeptidase Superfamily:Creatinase/aminopeptidase Family:Creatinase/aminopeptidase
Confidence and coverage
Confidence: | 100.0% | Coverage: | 99%
262 residues ( 99% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | A | I | S | I | K | T | P | E | D | I | E | K | M | R | V | A | G | R | L | A | A | E | V | L | E | M | I | E | P | Y | V | K | P | G | V | S | T | G | E | L | D | R | I | C | N | D | Y | I | V | N | E | Q | H | A | V | S | A | C | L
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | G | Y | H | G | Y | P | K | S | V | C | I | S | I | N | E | V | V | C | H | G | I | P | D | D | A | K | L | L | K | D | G | D | I | V | N | I | D | V | T | V | I | K | D | G | F | H | G | D | T | S | K | M | F | I | V | G | K | P | T | I
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | M | G | E | R | L | C | R | I | T | Q | E | S | L | Y | L | A | L | R | M | V | K | P | G | I | N | L | R | E | I | G | A | A | I | Q | K | F | V | E | A | E | G | F | S | V | V | R | E | Y | C | G | H | G | I | G | R | G | F | H | E | E
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240
Sequence |  | P | Q | V | L | H | Y | D | S | R | E | T | N | V | V | L | K | P | G | M | T | F | T | I | E | P | M | V | N | A | G | K | K | E | I | R | T | M | K | D | G | W | T | V | K | T | K | D | R | S | L | S | A | Q | Y | E | H | T | I | V | V
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | .
Sequence |  | T | D | N | G | C | E | I | L | T | L | R | K | D | D | T | I | P | A | I | I | S | H | D | E
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| d2gg2a1 |

### PDB 2gg2 chain A domain 1

Region: 3 - 264
Aligned: 262
Modelled: 262
Confidence: 100.0%
Identity: 100%
Fold: Creatinase/aminopeptidase
Superfamily: Creatinase/aminopeptidase
Family: Creatinase/aminopeptidase

Phyre2
2 |
| c2g6pA_ |

### PDB 2g6p chain A

Region: 2 - 261
Aligned: 258
Modelled: 260
Confidence: 100.0%
Identity: 47%
PDB header:hydrolase
Chain: A: PDB Molecule:methionine aminopeptidase 1;
PDBTitle: crystal structure of truncated (delta 1-89) human methionine2 aminopeptidase type 1 in complex with pyridyl pyrimidine derivative

Phyre2
3 |
| c2gz5A_ |

### PDB 2gz5 chain A

Region: 2 - 261
Aligned: 258
Modelled: 260
Confidence: 100.0%
Identity: 47%
PDB header:hydrolase
Chain: A: PDB Molecule:methionine aminopeptidase 1;
PDBTitle: human type 1 methionine aminopeptidase in complex with ovalicin at 1.12 ang

Phyre2
4 |
| c3s6bA_ |

### PDB 3s6b chain A

Region: 3 - 264
Aligned: 260
Modelled: 262
Confidence: 100.0%
Identity: 42%
PDB header:hydrolase
Chain: A: PDB Molecule:methionine aminopeptidase;
PDBTitle: crystal structure of methionine aminopeptidase 1b from plasmodium2 falciparum, pf10_0150

Phyre2
5 |
| c3tavA_ |

### PDB 3tav chain A

Region: 1 - 252
Aligned: 251
Modelled: 252
Confidence: 100.0%
Identity: 37%
PDB header:hydrolase
Chain: A: PDB Molecule:methionine aminopeptidase;
PDBTitle: crystal structure of a methionine aminopeptidase from mycobacterium2 abscessus

Phyre2
6 |
| c3mx6A_ |

### PDB 3mx6 chain A

Region: 3 - 255
Aligned: 251
Modelled: 253
Confidence: 100.0%
Identity: 52%
PDB header:hydrolase
Chain: A: PDB Molecule:methionine aminopeptidase;
PDBTitle: crystal structure of methionine aminopeptidase from rickettsia2 prowazekii bound to methionine

Phyre2
7 |
| c1yj3A_ |

### PDB 1yj3 chain A

Region: 1 - 250
Aligned: 247
Modelled: 250
Confidence: 100.0%
Identity: 51%
PDB header:hydrolase
Chain: A: PDB Molecule:methionine aminopeptidase;
PDBTitle: crystal structure analysis of product bound methionine2 aminopeptidase type 1c from mycobacterium tuberculosis

Phyre2
8 |
| d1o0xa_ |

### PDB 1o0x chain A

Region: 3 - 250
Aligned: 247
Modelled: 248
Confidence: 100.0%
Identity: 43%
Fold: Creatinase/aminopeptidase
Superfamily: Creatinase/aminopeptidase
Family: Creatinase/aminopeptidase

Phyre2
9 |
| c1w7vD_ |

### PDB 1w7v chain D

Region: 1 - 261
Aligned: 240
Modelled: 253
Confidence: 100.0%
Identity: 28%
PDB header:hydrolase
Chain: D: PDB Molecule:xaa-pro aminopeptidase;
PDBTitle: znmg substituted aminopeptidase p from e. coli

Phyre2
10 |
| c2oknB_ |

### PDB 2okn chain B

Region: 1 - 262
Aligned: 256
Modelled: 262
Confidence: 100.0%
Identity: 22%
PDB header:hydrolase
Chain: B: PDB Molecule:xaa-pro dipeptidase;
PDBTitle: crystal strcture of human prolidase

Phyre2
11 |
| d1qxya_ |

### PDB 1qxy chain A

Region: 3 - 250
Aligned: 246
Modelled: 248
Confidence: 100.0%
Identity: 33%
Fold: Creatinase/aminopeptidase
Superfamily: Creatinase/aminopeptidase
Family: Creatinase/aminopeptidase

Phyre2
12 |
| c3l24A_ |

### PDB 3l24 chain A

Region: 1 - 253
Aligned: 241
Modelled: 253
Confidence: 100.0%
Identity: 17%
PDB header:hydrolase
Chain: A: PDB Molecule:xaa-pro dipeptidase;
PDBTitle: crystal structure of the nerve agent degrading2 organophosphate anhydrolase/prolidase in complex with3 inhibitors

Phyre2
13 |
| c1chmA_ |

### PDB 1chm chain A

Region: 1 - 260
Aligned: 245
Modelled: 247
Confidence: 100.0%
Identity: 18%
PDB header:creatinase
Chain: A: PDB Molecule:creatine amidinohydrolase;
PDBTitle: enzymatic mechanism of creatine amidinohydrolase as deduced2 from crystal structures

Phyre2
14 |
| c2zsgB_ |

### PDB 2zsg chain B

Region: 1 - 256
Aligned: 227
Modelled: 239
Confidence: 100.0%
Identity: 22%
PDB header:hydrolase
Chain: B: PDB Molecule:aminopeptidase p, putative;
PDBTitle: crystal structure of x-pro aminopeptidase from thermotoga maritima2 msb8

Phyre2
15 |
| d1chma2 |

### PDB 1chm chain A domain 2

Region: 5 - 260
Aligned: 242
Modelled: 243
Confidence: 100.0%
Identity: 18%
Fold: Creatinase/aminopeptidase
Superfamily: Creatinase/aminopeptidase
Family: Creatinase/aminopeptidase

Phyre2
16 |
| c3ig4E_ |

### PDB 3ig4 chain E

Region: 1 - 262
Aligned: 231
Modelled: 237
Confidence: 100.0%
Identity: 22%
PDB header:hydrolase
Chain: E: PDB Molecule:xaa-pro aminopeptidase;
PDBTitle: structure of a putative aminopeptidase p from bacillus anthracis

Phyre2
17 |
| c1wy2B_ |

### PDB 1wy2 chain B

Region: 3 - 256
Aligned: 226
Modelled: 237
Confidence: 100.0%
Identity: 24%
PDB header:hydrolase
Chain: B: PDB Molecule:xaa-pro dipeptidase;
PDBTitle: crystal structure of the prolidase from pyrococcus horikoshii ot3

Phyre2
18 |
| c3q6dA_ |

### PDB 3q6d chain A

Region: 1 - 256
Aligned: 227
Modelled: 239
Confidence: 100.0%
Identity: 27%
PDB header:viral protein
Chain: A: PDB Molecule:proline dipeptidase;
PDBTitle: xaa-pro dipeptidase from bacillus anthracis.

Phyre2
19 |
| c2howB_ |

### PDB 2how chain B

Region: 1 - 256
Aligned: 226
Modelled: 235
Confidence: 100.0%
Identity: 25%
PDB header:hydrolase
Chain: B: PDB Molecule:356aa long hypothetical dipeptidase;
PDBTitle: dipeptidase (ph0974) from pyrococcus horikoshii ot3

Phyre2
20 |
| c3cb5A_ |

### PDB 3cb5 chain A

Region: 3 - 258
Aligned: 244
Modelled: 249
Confidence: 100.0%
Identity: 14%
PDB header:transcription
Chain: A: PDB Molecule:fact complex subunit spt16;
PDBTitle: crystal structure of the s. pombe peptidase homology domain of fact2 complex subunit spt16 (form a)

Phyre2
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Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | d2gg2a1 |
|  | 100.0 | 100 | Fold:Creatinase/aminopeptidase Superfamily:Creatinase/aminopeptidase Family:Creatinase/aminopeptidase
2 | c2g6pA_ |
|  | 100.0 | 47 | PDB header:hydrolase Chain: A: PDB Molecule:methionine aminopeptidase 1; PDBTitle: crystal structure of truncated (delta 1-89) human methionine2 aminopeptidase type 1 in complex with pyridyl pyrimidine derivative
3 | c2gz5A_ |
|  | 100.0 | 47 | PDB header:hydrolase Chain: A: PDB Molecule:methionine aminopeptidase 1; PDBTitle: human type 1 methionine aminopeptidase in complex with ovalicin at 1.12 ang
4 | c3s6bA_ |
|  | 100.0 | 42 | PDB header:hydrolase Chain: A: PDB Molecule:methionine aminopeptidase; PDBTitle: crystal structure of methionine aminopeptidase 1b from plasmodium2 falciparum, pf10_0150
5 | c3tavA_ |
|  | 100.0 | 37 | PDB header:hydrolase Chain: A: PDB Molecule:methionine aminopeptidase; PDBTitle: crystal structure of a methionine aminopeptidase from mycobacterium2 abscessus
6 | c3mx6A_ |
|  | 100.0 | 52 | PDB header:hydrolase Chain: A: PDB Molecule:methionine aminopeptidase; PDBTitle: crystal structure of methionine aminopeptidase from rickettsia2 prowazekii bound to methionine
7 | c1yj3A_ |
|  | 100.0 | 51 | PDB header:hydrolase Chain: A: PDB Molecule:methionine aminopeptidase; PDBTitle: crystal structure analysis of product bound methionine2 aminopeptidase type 1c from mycobacterium tuberculosis
8 | d1o0xa_ |
|  | 100.0 | 43 | Fold:Creatinase/aminopeptidase Superfamily:Creatinase/aminopeptidase Family:Creatinase/aminopeptidase
9 | c1w7vD_ |
|  | 100.0 | 28 | PDB header:hydrolase Chain: D: PDB Molecule:xaa-pro aminopeptidase; PDBTitle: znmg substituted aminopeptidase p from e. coli
10 | c2oknB_ |
|  | 100.0 | 22 | PDB header:hydrolase Chain: B: PDB Molecule:xaa-pro dipeptidase; PDBTitle: crystal strcture of human prolidase
11 | d1qxya_ |
|  | 100.0 | 33 | Fold:Creatinase/aminopeptidase Superfamily:Creatinase/aminopeptidase Family:Creatinase/aminopeptidase
12 | c3l24A_ |
|  | 100.0 | 17 | PDB header:hydrolase Chain: A: PDB Molecule:xaa-pro dipeptidase; PDBTitle: crystal structure of the nerve agent degrading2 organophosphate anhydrolase/prolidase in complex with3 inhibitors
13 | c1chmA_ |
|  | 100.0 | 18 | PDB header:creatinase Chain: A: PDB Molecule:creatine amidinohydrolase; PDBTitle: enzymatic mechanism of creatine amidinohydrolase as deduced2 from crystal structures
14 | c2zsgB_ |
|  | 100.0 | 22 | PDB header:hydrolase Chain: B: PDB Molecule:aminopeptidase p, putative; PDBTitle: crystal structure of x-pro aminopeptidase from thermotoga maritima2 msb8
15 | d1chma2 |
|  | 100.0 | 18 | Fold:Creatinase/aminopeptidase Superfamily:Creatinase/aminopeptidase Family:Creatinase/aminopeptidase
16 | c3ig4E_ |
|  | 100.0 | 22 | PDB header:hydrolase Chain: E: PDB Molecule:xaa-pro aminopeptidase; PDBTitle: structure of a putative aminopeptidase p from bacillus anthracis
17 | c1wy2B_ |
|  | 100.0 | 24 | PDB header:hydrolase Chain: B: PDB Molecule:xaa-pro dipeptidase; PDBTitle: crystal structure of the prolidase from pyrococcus horikoshii ot3
18 | c3q6dA_ |
|  | 100.0 | 27 | PDB header:viral protein Chain: A: PDB Molecule:proline dipeptidase; PDBTitle: xaa-pro dipeptidase from bacillus anthracis.
19 | c2howB_ |
|  | 100.0 | 25 | PDB header:hydrolase Chain: B: PDB Molecule:356aa long hypothetical dipeptidase; PDBTitle: dipeptidase (ph0974) from pyrococcus horikoshii ot3
20 | c3cb5A_ |
|  | 100.0 | 14 | PDB header:transcription Chain: A: PDB Molecule:fact complex subunit spt16; PDBTitle: crystal structure of the s. pombe peptidase homology domain of fact2 complex subunit spt16 (form a)
21 | d1pv9a2 |
| not modelled | 100.0 | 25 | Fold:Creatinase/aminopeptidase Superfamily:Creatinase/aminopeptidase Family:Creatinase/aminopeptidase
22 | d2v3za2 |
| not modelled | 100.0 | 26 | Fold:Creatinase/aminopeptidase Superfamily:Creatinase/aminopeptidase Family:Creatinase/aminopeptidase
23 | d1b6aa2 |
| not modelled | 100.0 | 21 | Fold:Creatinase/aminopeptidase Superfamily:Creatinase/aminopeptidase Family:Creatinase/aminopeptidase
24 | c3ctzA_ |
| not modelled | 100.0 | 21 | PDB header:hydrolase Chain: A: PDB Molecule:xaa-pro aminopeptidase 1; PDBTitle: structure of human cytosolic x-prolyl aminopeptidase
25 | c2v6cA_ |
| not modelled | 100.0 | 23 | PDB header:transcription regulator Chain: A: PDB Molecule:proliferation-associated protein 2g4; PDBTitle: crystal structure of erbb3 binding protein 1 (ebp1)
26 | c2q8kA_ |
| not modelled | 100.0 | 24 | PDB header:transcription Chain: A: PDB Molecule:proliferation-associated protein 2g4; PDBTitle: the crystal structure of ebp1
27 | d1xgsa2 |
| not modelled | 100.0 | 31 | Fold:Creatinase/aminopeptidase Superfamily:Creatinase/aminopeptidase Family:Creatinase/aminopeptidase
28 | c3bitA_ |
| not modelled | 100.0 | 11 | PDB header:transcription Chain: A: PDB Molecule:fact complex subunit spt16; PDBTitle: crystal structure of yeast spt16 n-terminal domain
29 | c1xgnB_ |
| not modelled | 100.0 | 30 | PDB header:aminopeptidase Chain: B: PDB Molecule:methionine aminopeptidase; PDBTitle: methionine aminopeptidase from hyperthermophile pyrococcus2 furiosus
30 | c1b6aA_ |
| not modelled | 100.0 | 21 | PDB header:angiogenesis inhibitor Chain: A: PDB Molecule:methionine aminopeptidase; PDBTitle: human methionine aminopeptidase 2 complexed with tnp-470
31 | c3fm3B_ |
| not modelled | 100.0 | 22 | PDB header:hydrolase Chain: B: PDB Molecule:methionine aminopeptidase 2; PDBTitle: crystal structure of an encephalitozoon cuniculi methionine2 aminopeptidase type 2
32 | c1yw7A_ |
| not modelled | 100.0 | 24 | PDB header:hydrolase Chain: A: PDB Molecule:methionine aminopeptidase 2; PDBTitle: h-metap2 complexed with a444148
33 | c1kp0B_ |
| not modelled | 100.0 | 17 | PDB header:hydrolase Chain: B: PDB Molecule:creatine amidinohydrolase; PDBTitle: the crystal structure analysis of creatine amidinohydrolase2 from actinobacillus
34 | d1kp0a2 |
| not modelled | 100.0 | 17 | Fold:Creatinase/aminopeptidase Superfamily:Creatinase/aminopeptidase Family:Creatinase/aminopeptidase
35 | c3nojA_ |
| not modelled | 68.2 | 23 | PDB header:lyase Chain: A: PDB Molecule:4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate PDBTitle: the structure of hmg/cha aldolase from the protocatechuate degradation2 pathway of pseudomonas putida
36 | c2c5qE_ |
| not modelled | 66.3 | 16 | PDB header:structural genomics,unknown function Chain: E: PDB Molecule:rraa-like protein yer010c; PDBTitle: crystal structure of yeast yer010cp
37 | d1wi0a_ |
| not modelled | 28.9 | 23 | Fold:beta-Grasp (ubiquitin-like) Superfamily:CAD & PB1 domains Family:PB1 domain
38 | c3innB_ |
| not modelled | 27.9 | 17 | PDB header:ligase Chain: B: PDB Molecule:pantothenate synthetase; PDBTitle: crystal structure of pantoate-beta-alanine-ligase in complex2 with atp at low occupancy at 2.1 a resolution
39 | d2npta1 |
| not modelled | 27.1 | 23 | Fold:beta-Grasp (ubiquitin-like) Superfamily:CAD & PB1 domains Family:PB1 domain
40 | c3prdA_ |
| not modelled | 25.9 | 29 | PDB header:chaperone, isomerase Chain: A: PDB Molecule:fkbp-type peptidyl-prolyl cis-trans isomerase; PDBTitle: structural analysis of protein folding by the methanococcus jannaschii2 chaperone fkbp26
41 | d1e4cp_ |
| not modelled | 25.7 | 17 | Fold:AraD/HMP-PK domain-like Superfamily:AraD/HMP-PK domain-like Family:AraD-like aldolase/epimerase
42 | c2fk5B_ |
| not modelled | 24.9 | 15 | PDB header:lyase Chain: B: PDB Molecule:fuculose-1-phosphate aldolase; PDBTitle: crystal structure of l-fuculose-1-phosphate aldolase from thermus2 thermophilus hb8
43 | d1kt0a2 |
| not modelled | 24.0 | 31 | Fold:FKBP-like Superfamily:FKBP-like Family:FKBP immunophilin/proline isomerase
44 | c2l25A_ |
| not modelled | 21.3 | 10 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: np_888769.1
45 | c3ds8A_ |
| not modelled | 20.5 | 21 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:lin2722 protein; PDBTitle: the crysatl structure of the gene lin2722 products from listeria2 innocua
46 | c2y0oA_ |
| not modelled | 20.3 | 26 | PDB header:isomerase Chain: A: PDB Molecule:probable d-lyxose ketol-isomerase; PDBTitle: the structure of a d-lyxose isomerase from the sigmab2 regulon of bacillus subtilis
47 | c2ki0A_ |
| not modelled | 19.8 | 14 | PDB header:de novo protein Chain: A: PDB Molecule:ds119; PDBTitle: nmr structure of a de novo designed beta alpha beta
48 | c2kw0A_ |
| not modelled | 19.4 | 13 | PDB header:oxidoreductase Chain: A: PDB Molecule:ccmh protein; PDBTitle: solution structure of n-terminal domain of ccmh from escherichia.coli
49 | c2hl7A_ |
| not modelled | 18.9 | 23 | PDB header:oxidoreductase Chain: A: PDB Molecule:cytochrome c-type biogenesis protein ccmh; PDBTitle: crystal structure of the periplasmic domain of ccmh from pseudomonas2 aeruginosa
50 | c2zyiB_ |
| not modelled | 16.6 | 18 | PDB header:hydrolase Chain: B: PDB Molecule:lipase, putative; PDBTitle: a. fulgidus lipase with fatty acid fragment and calcium
51 | c2pc9B_ |
| not modelled | 16.3 | 14 | PDB header:lyase Chain: B: PDB Molecule:phosphoenolpyruvate carboxykinase [atp]; PDBTitle: crystal structure of atp-dependent phosphoenolpyruvate carboxykinase2 from thermus thermophilus hb8
52 | d1ex9a_ |
| not modelled | 14.3 | 17 | Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Bacterial lipase
53 | c3mpbA_ |
| not modelled | 14.2 | 19 | PDB header:isomerase Chain: A: PDB Molecule:sugar isomerase; PDBTitle: z5688 from e. coli o157:h7 bound to fructose
54 | c3k4iC_ |
| not modelled | 13.6 | 13 | PDB header:structural genomics, unknown function Chain: C: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of uncharacterized protein pspto_3204 from2 pseudomonas syringae pv. tomato str. dc3000
55 | d1l1pa_ |
| not modelled | 12.9 | 35 | Fold:FKBP-like Superfamily:FKBP-like Family:FKBP immunophilin/proline isomerase
56 | c2xs4A_ |
| not modelled | 12.9 | 13 | PDB header:hydrolase Chain: A: PDB Molecule:karilysin protease; PDBTitle: structure of karilysin catalytic mmp domain in complex with2 magnesium
57 | c2opiB_ |
| not modelled | 12.7 | 20 | PDB header:lyase Chain: B: PDB Molecule:l-fuculose-1-phosphate aldolase; PDBTitle: crystal structure of l-fuculose-1-phosphate aldolase from bacteroides2 thetaiotaomicron
58 | d1cvla_ |
| not modelled | 12.6 | 21 | Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Bacterial lipase
59 | d1ii2a1 |
| not modelled | 12.5 | 18 | Fold:PEP carboxykinase-like Superfamily:PEP carboxykinase-like Family:PEP carboxykinase C-terminal domain
60 | c2vavL_ |
| not modelled | 12.5 | 13 | PDB header:transferase Chain: L: PDB Molecule:acetyl-coa--deacetylcephalosporin c PDBTitle: crystal structure of deacetylcephalosporin c2 acetyltransferase (dac-soak)
61 | d1k8qa_ |
| not modelled | 12.3 | 25 | Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Gastric lipase
62 | c3i1iA_ |
| not modelled | 11.8 | 12 | PDB header:transferase Chain: A: PDB Molecule:homoserine o-acetyltransferase; PDBTitle: x-ray crystal structure of homoserine o-acetyltransferase from2 bacillus anthracis
63 | d2dsta1 |
| not modelled | 10.8 | 15 | Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:TTHA1544-like
64 | c1ahuB_ |
| not modelled | 10.8 | 22 | PDB header:flavoenzyme Chain: B: PDB Molecule:vanillyl-alcohol oxidase; PDBTitle: structure of the octameric flavoenzyme vanillyl-alcohol2 oxidase in complex with p-cresol
65 | d1w26a3 |
| not modelled | 10.7 | 21 | Fold:FKBP-like Superfamily:FKBP-like Family:FKBP immunophilin/proline isomerase
66 | c3lp5A_ |
| not modelled | 10.7 | 21 | PDB header:hydrolase Chain: A: PDB Molecule:putative cell surface hydrolase; PDBTitle: the crystal structure of the putative cell surface hydrolase from2 lactobacillus plantarum wcfs1
67 | d4lipd_ |
| not modelled | 10.4 | 21 | Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Bacterial lipase
68 | c2k5nA_ |
| not modelled | 10.3 | 16 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative cold-shock protein; PDBTitle: solution nmr structure of the n-terminal domain of protein2 eca1580 from erwinia carotovora, northeast structural3 genomics consortium target ewr156a
69 | d1j3ba1 |
| not modelled | 10.1 | 11 | Fold:PEP carboxykinase-like Superfamily:PEP carboxykinase-like Family:PEP carboxykinase C-terminal domain
70 | c2irpA_ |
| not modelled | 10.0 | 27 | PDB header:lyase Chain: A: PDB Molecule:putative aldolase class 2 protein aq_1979; PDBTitle: crystal structure of the l-fuculose-1-phosphate aldolase (aq_1979)2 from aquifex aeolicus vf5
71 | d1tiaa_ |
| not modelled | 9.8 | 18 | Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Fungal lipases
72 | d1m1fa_ |
| not modelled | 9.3 | 12 | Fold:SH3-like barrel Superfamily:Cell growth inhibitor/plasmid maintenance toxic component Family:Kid/PemK
73 | d2vata1 |
| not modelled | 9.2 | 15 | Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:O-acetyltransferase
74 | d1t11a3 |
| not modelled | 9.1 | 30 | Fold:FKBP-like Superfamily:FKBP-like Family:FKBP immunophilin/proline isomerase
75 | d3tgla_ |
| not modelled | 9.0 | 21 | Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Fungal lipases
76 | c3fmyA_ |
| not modelled | 9.0 | 26 | PDB header:dna binding protein Chain: A: PDB Molecule:hth-type transcriptional regulator mqsa PDBTitle: structure of the c-terminal domain of the e. coli protein2 mqsa (ygit/b3021)
77 | c3ocrA_ |
| not modelled | 8.9 | 10 | PDB header:lyase Chain: A: PDB Molecule:class ii aldolase/adducin domain protein; PDBTitle: crystal structure of aldolase ii superfamily protein from pseudomonas2 syringae
78 | d2pl5a1 |
| not modelled | 8.8 | 21 | Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:O-acetyltransferase
79 | d1rp1a2 |
| not modelled | 8.5 | 14 | Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Pancreatic lipase, N-terminal domain
80 | d1tiba_ |
| not modelled | 8.2 | 14 | Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Fungal lipases
81 | c2gacA_ |
| not modelled | 8.1 | 14 | PDB header:hydrolase Chain: A: PDB Molecule:glycosylasparaginase; PDBTitle: t152c mutant glycosylasparaginase from flavobacterium2 meningosepticum
82 | d1lgya_ |
| not modelled | 8.1 | 18 | Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Fungal lipases
83 | d1cxva_ |
| not modelled | 8.1 | 19 | Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain
84 | c1t3mA_ |
| not modelled | 8.0 | 9 | PDB header:hydrolase Chain: A: PDB Molecule:putative l-asparaginase; PDBTitle: structure of the isoaspartyl peptidase with l-asparaginase2 activity from e. coli
85 | d1uwca_ |
| not modelled | 7.7 | 11 | Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Fungal lipases
86 | d1y7ma2 |
| not modelled | 7.7 | 19 | Fold:LysM domain Superfamily:LysM domain Family:LysM domain
87 | d1hpla2 |
| not modelled | 7.7 | 17 | Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Pancreatic lipase, N-terminal domain
88 | c1kt0A_ |
| not modelled | 7.7 | 27 | PDB header:isomerase Chain: A: PDB Molecule:51 kda fk506-binding protein; PDBTitle: structure of the large fkbp-like protein, fkbp51, involved in steroid2 receptor complexes
89 | d1lpbb2 |
| not modelled | 7.6 | 24 | Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Pancreatic lipase, N-terminal domain
90 | d2olra1 |
| not modelled | 7.6 | 13 | Fold:PEP carboxykinase-like Superfamily:PEP carboxykinase-like Family:PEP carboxykinase C-terminal domain
91 | c3jr1A_ |
| not modelled | 7.5 | 6 | PDB header:transferase Chain: A: PDB Molecule:putative fructosamine-3-kinase; PDBTitle: crystal structure of putative fructosamine-3-kinase2 (yp_719053.1) from haemophilus somnus 129pt at 2.32 a3 resolution
92 | d1g6pa_ |
| not modelled | 7.3 | 22 | Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like
93 | c2zakB_ |
| not modelled | 7.2 | 9 | PDB header:hydrolase Chain: B: PDB Molecule:l-asparaginase precursor; PDBTitle: orthorhombic crystal structure of precursor e. coli isoaspartyl2 peptidase/l-asparaginase (ecaiii) with active-site t179a mutation
94 | c2pplA_ |
| not modelled | 7.1 | 10 | PDB header:hydrolase Chain: A: PDB Molecule:pancreatic lipase-related protein 1; PDBTitle: human pancreatic lipase-related protein 1
95 | d1etha2 |
| not modelled | 7.1 | 21 | Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Pancreatic lipase, N-terminal domain
96 | c2kxxA_ |
| not modelled | 6.9 | 5 | PDB header:protein binding Chain: A: PDB Molecule:small protein a; PDBTitle: nmr structure of escherichia coli bame, a lipoprotein component of the2 beta-barrel assembly machinery complex
97 | c2gezE_ |
| not modelled | 6.8 | 9 | PDB header:hydrolase Chain: E: PDB Molecule:l-asparaginase alpha subunit; PDBTitle: crystal structure of potassium-independent plant asparaginase
98 | d1tcaa_ |
| not modelled | 6.8 | 14 | Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Fungal lipases
99 | c2k5jB_ |
| not modelled | 6.7 | 8 | PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein yiif; PDBTitle: solution structure of protein yiif from shigella flexneri2 serotype 5b (strain 8401) . northeast structural genomics3 consortium target sft1

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0