BLASTP 2.2.22 [Sep-27-2009]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= batch____
         (397 letters)

Database: uniref50.fasta 
           3,077,464 sequences; 1,040,396,356 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_A6VPD9 Tryptophan synthase beta chain n=265 Tax=cellula...   681   0.0  
UniRef50_B0TP63 Tryptophan synthase beta chain n=124 Tax=cellula...   639   0.0  
UniRef50_Q7VR00 Tryptophan synthase beta chain n=5 Tax=Bacteria ...   573   e-162
UniRef50_C5V964 Tryptophan synthase, beta subunit n=2 Tax=Coryne...   498   e-139
UniRef50_P25269 Tryptophan synthase beta chain 2, chloroplastic ...   440   e-122
UniRef50_C9KJ78 Tryptophan synthase, beta subunit n=1 Tax=Mitsuo...   434   e-120
UniRef50_D2LTS0 Tryptophan synthase, beta subunit n=1 Tax=Bacill...   430   e-119
UniRef50_B1XY48 Tryptophan synthase beta chain n=287 Tax=cellula...   427   e-118
UniRef50_A1KSW2 Tryptophan synthase beta chain n=49 Tax=Bacteria...   426   e-118
UniRef50_A5UMB9 Tryptophan synthase, beta subunit, TrpB n=5 Tax=...   422   e-116
UniRef50_B7FQI2 Predicted protein n=1 Tax=Phaeodactylum tricornu...   421   e-116
UniRef50_P00931 Tryptophan synthase n=45 Tax=Eukaryota RepID=TRP...   413   e-114
UniRef50_Q2S700 Tryptophan synthase, beta subunit n=6 Tax=Bacter...   405   e-111
UniRef50_D1HPU5 Whole genome shotgun sequence of line PN40024, s...   387   e-106
UniRef50_Q0RGR3 Tryptophan synthase, beta protein n=2 Tax=Actino...   383   e-105
UniRef50_Q822W9 Tryptophan synthase beta chain 1 n=8 Tax=Bacteri...   382   e-104
UniRef50_Q7VGA7 Tryptophan synthase beta chain n=4 Tax=Proteobac...   374   e-102
UniRef50_D2VKV7 Predicted protein n=1 Tax=Naegleria gruberi RepI...   373   e-102
UniRef50_B2TM49 Tryptophan synthase beta chain n=40 Tax=cellular...   369   e-100
UniRef50_C0NSJ2 Bifunctional tryptophan synthase TRPB n=1 Tax=Aj...   368   e-100
UniRef50_B2KCI5 Tryptophan synthase beta chain n=2 Tax=Bacteria ...   367   e-100
UniRef50_D0JB95 Bifunctional phosphoribosylanthranilate isomeras...   367   e-100
UniRef50_A8Z5Y3 Putative tryptophan synthase, beta subunit (TrpB...   367   e-100
UniRef50_B0R332 Tryptophan synthase beta chain n=8 Tax=cellular ...   367   e-100
UniRef50_C1FGK1 Predicted protein n=14 Tax=cellular organisms Re...   343   6e-93
UniRef50_B0ZSJ6 Tryptophan synthase beta subunit n=3 Tax=rosids ...   335   2e-90
UniRef50_C0QZH7 Tryptophan synthase beta subunit n=4 Tax=Bacteri...   327   4e-88
UniRef50_B7G4U3 Tryptophan synthase, beta chain n=3 Tax=cellular...   307   4e-82
UniRef50_B8MZR1 Trytophan synthase alpha subunit, putative n=2 T...   296   1e-78
UniRef50_D1NGU1 DNA (Cytosine-5-)-methyltransferase (Fragment) n...   295   2e-78
UniRef50_Q1V1Q0 Tryptophan synthase beta chain 1 n=6 Tax=root Re...   278   3e-73
UniRef50_B6HPP8 Pc22g00910 protein n=1 Tax=Penicillium chrysogen...   264   5e-69
UniRef50_A1DP73 Tryptophan synthase n=4 Tax=Trichocomaceae RepID...   256   1e-66
UniRef50_C8VGH6 Putative uncharacterized protein n=2 Tax=Emerice...   224   5e-57
UniRef50_Q56YC7 Tryptophan synthase beta chain 1 n=3 Tax=cellula...   144   8e-33
UniRef50_Q9Y8T5 Tryptophan synthase beta chain 1 n=10 Tax=Thermo...   134   6e-30
UniRef50_B6YSU5 Tryptophan synthase beta chain n=232 Tax=cellula...   134   8e-30
UniRef50_C7N0P7 Pyridoxal-phosphate dependent TrpB-like enzyme n...   113   1e-23
UniRef50_Q9WZ09 Tryptophan synthase beta chain 2 n=6 Tax=Bacteri...   107   8e-22
UniRef50_A8F8F7 Tryptophan synthase beta chain n=12 Tax=cellular...   106   1e-21
UniRef50_B1KQQ7 Pyridoxal-5'-phosphate-dependent protein beta su...   103   9e-21
UniRef50_C7DG26 Pyridoxal-phosphate dependent TrpB-like enzyme n...   100   2e-19
UniRef50_D2L2T8 Pyridoxal-phosphate dependent TrpB-like enzyme n...    96   2e-18
UniRef50_A8M857 Pyridoxal-5'-phosphate-dependent protein beta su...    95   4e-18
UniRef50_C7GZ56 Tryptophan synthase beta chain 2 n=3 Tax=Bacteri...    92   2e-17
UniRef50_Q970N1 Tryptophan synthase beta chain 2 n=16 Tax=Archae...    92   2e-17
UniRef50_O05626 Tryptophan synthase beta subunit (Fragment) n=1 ...    89   3e-16
UniRef50_A8HUC1 Tryptophan synthase beta subunit (Fragment) n=1 ...    89   4e-16
UniRef50_Q44051 Transposon Mu dl-R insertion site. (Fragment) n=...    87   1e-15
UniRef50_Q13AA2 Tryptophan synthase, beta chain-like n=7 Tax=Bac...    86   3e-15
UniRef50_C1SGJ4 Tryptophan synthase beta chain n=1 Tax=Denitrovi...    85   6e-15
UniRef50_C6TEW3 Putative uncharacterized protein (Fragment) n=1 ...    60   1e-07
UniRef50_B9SZR5 Tryptophan synthase beta chain, putative n=1 Tax...    54   1e-05
UniRef50_D1C1V4 Threonine synthase n=3 Tax=Bacteria RepID=D1C1V4...    51   7e-05
UniRef50_D1BQL6 Cysteine synthase n=9 Tax=Firmicutes RepID=D1BQL...    46   0.003
UniRef50_A3DKP7 L-threonine synthase n=2 Tax=Desulfurococcaceae ...    46   0.003
UniRef50_Q6C6D8 YALI0E10307p n=1 Tax=Yarrowia lipolytica RepID=Q...    46   0.003
UniRef50_B9JX06 Threonine dehydratase n=16 Tax=Alphaproteobacter...    46   0.003
UniRef50_UPI0001903713 tryptophan synthase subunit beta n=1 Tax=...    45   0.004
UniRef50_A2ETD5 Threonine synthase family protein n=1 Tax=Tricho...    45   0.006
UniRef50_B0VGY7 Putative threonine synthase n=1 Tax=Candidatus C...    44   0.008
UniRef50_P14552 Tryptophan synthase beta chain (Fragment) n=9 Ta...    44   0.008
UniRef50_C6A2V6 Threonine dehydratase n=1 Tax=Thermococcus sibir...    43   0.017
UniRef50_Q58860 Probable threonine synthase n=38 Tax=Archaea Rep...    43   0.017
UniRef50_C1PE10 Threonine dehydratase n=2 Tax=Bacillaceae RepID=...    43   0.017
UniRef50_Q04513 Threonine dehydratase biosynthetic n=34 Tax=Acti...    43   0.019
UniRef50_A1KYC1 Serine dehydratase n=1 Tax=Aplysia californica R...    43   0.022
UniRef50_A0LFH6 Cysteine synthases n=15 Tax=cellular organisms R...    42   0.027
UniRef50_A8F1M7 Threonine dehydratase n=20 Tax=cellular organism...    42   0.027
UniRef50_Q9ZMW6 Cysteine synthase n=44 Tax=Bacteria RepID=CYSM_H...    42   0.028
UniRef50_B6A2K1 Pyridoxal-5'-phosphate-dependent protein beta su...    42   0.028
UniRef50_Q1IJB6 L-threonine synthase n=2 Tax=Bacteria RepID=Q1IJ...    42   0.032
UniRef50_B9L1Z4 Threonine synthase n=1 Tax=Thermomicrobium roseu...    42   0.034
UniRef50_A3ERN7 Cysteine synthase n=2 Tax=Leptospirillum sp. Gro...    42   0.042
UniRef50_Q2L695 Aspartate racemase n=3 Tax=Coelomata RepID=Q2L69...    42   0.043
UniRef50_B4AUD2 Threonine synthase, putative n=23 Tax=Francisell...    42   0.044
UniRef50_Q3KMJ4 Tryptophan synthase beta chain n=1 Tax=Chlamydia...    42   0.056
UniRef50_D0LAQ5 Threonine dehydratase n=6 Tax=Actinomycetales Re...    42   0.057
UniRef50_B2KE33 Threonine synthase n=1 Tax=Elusimicrobium minutu...    41   0.061
UniRef50_UPI000180C4E2 PREDICTED: similar to Serine racemase n=1...    41   0.065

>UniRef50_A6VPD9 Tryptophan synthase beta chain n=265 Tax=cellular organisms
           RepID=TRPB_ACTSZ
          Length = 398

 Score =  681 bits (1757), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 321/395 (81%), Positives = 355/395 (89%)

Query: 3   TLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKC 62
           T+LNPYFGEFGGMYVP+IL+P L+QLE+AFV A+ DP+FQ +F DLLKNYAGRPTALT C
Sbjct: 4   TILNPYFGEFGGMYVPEILVPVLQQLEKAFVEARNDPDFQQEFQDLLKNYAGRPTALTLC 63

Query: 63  QNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALA 122
           +N+T GT T LYLKREDLLHGGAHKTNQVLGQ LLAKRMGKT IIAETGAGQHGVA+ALA
Sbjct: 64  RNLTKGTKTKLYLKREDLLHGGAHKTNQVLGQILLAKRMGKTRIIAETGAGQHGVATALA 123

Query: 123 SALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYE 182
            A+L + CR+YMG+KDVERQSPNVFRMRLMG EV+PV  GS +LKDAC EA+RDWS +YE
Sbjct: 124 CAMLDMPCRVYMGSKDVERQSPNVFRMRLMGTEVVPVEKGSCSLKDACCEAMRDWSANYE 183

Query: 183 TAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFA 242
             HY+LGTAAGPHP+PTIVREFQ+MIGEETK QILE+EG LPDAVIA VGGGSNAIGMF 
Sbjct: 184 NTHYLLGTAAGPHPFPTIVREFQKMIGEETKRQILEKEGCLPDAVIAAVGGGSNAIGMFT 243

Query: 243 DFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISA 302
           DFI+ETNV LIGVEP G GIETGEHGAPLKHG+ GIYFGMK+P+MQTEDGQIEESYSISA
Sbjct: 244 DFIDETNVRLIGVEPAGKGIETGEHGAPLKHGKTGIYFGMKSPIMQTEDGQIEESYSISA 303

Query: 303 GLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMM 362
           GLDFPSVGPQHAYLNS GRA+Y SITDDEAL AFK L  HEGIIPALESSHALA ALKM+
Sbjct: 304 GLDFPSVGPQHAYLNSIGRAEYPSITDDEALAAFKELAKHEGIIPALESSHALAQALKMI 363

Query: 363 RENPDKEQLLVVNLSGRGDKDIFTVHDILKARGEI 397
           + NP+KEQLLVVNLSGRGDKDIFTV  IL+A+GE+
Sbjct: 364 KSNPEKEQLLVVNLSGRGDKDIFTVDKILRAKGEL 398


>UniRef50_B0TP63 Tryptophan synthase beta chain n=124 Tax=cellular organisms
           RepID=TRPB_SHEHH
          Length = 419

 Score =  639 bits (1647), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 307/388 (79%), Positives = 340/388 (87%), Gaps = 1/388 (0%)

Query: 5   LNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQN 64
           LNPYFGE+GGMYVPQILMPAL+QLE AF+ AQ+D  FQ +F DLLKNYAGRPTALT  +N
Sbjct: 4   LNPYFGEYGGMYVPQILMPALKQLETAFIEAQEDEAFQEEFTDLLKNYAGRPTALTLTRN 63

Query: 65  ITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASA 124
           ++      +YLKREDLLHGGAHKTNQVLGQALLAKRMGK EIIAETGAGQHGVA+ALA A
Sbjct: 64  LSPNPLAKIYLKREDLLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVATALACA 123

Query: 125 LLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETA 184
           LLGLKCR+YMGAKDVERQSPNVFRM+LMGAEVIPV SGSATLKDACNEA+RDWSG Y+ A
Sbjct: 124 LLGLKCRVYMGAKDVERQSPNVFRMKLMGAEVIPVTSGSATLKDACNEAMRDWSGCYDKA 183

Query: 185 HYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADF 244
           HY+LGTAAGPHPYPTIVREFQRMIG ETK QILEREGRLPDAVIACVGGGSNAIGMFADF
Sbjct: 184 HYLLGTAAGPHPYPTIVREFQRMIGAETKRQILEREGRLPDAVIACVGGGSNAIGMFADF 243

Query: 245 INETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGL 304
           I+E  V LIGVEP G GI+T  HGAPL HG+ GI+FGMKAP+MQ  +GQ+EESYS+SAGL
Sbjct: 244 IDEPEVALIGVEPAGKGIDTPMHGAPLHHGKTGIFFGMKAPLMQDSEGQVEESYSVSAGL 303

Query: 305 DFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRE 364
           DFPSVGPQHA+L + GRA Y S TDDEALE F+ L   EGIIPALES+HA+A+A+K+ +E
Sbjct: 304 DFPSVGPQHAHLAAIGRATYESATDDEALETFQLLARCEGIIPALESAHAIAYAVKLAKE 363

Query: 365 NPDKEQLLVVNLSGRGDKDIFTVHDILK 392
              KE LLVVNLSGRGDKDIFTV DIL+
Sbjct: 364 -ATKETLLVVNLSGRGDKDIFTVADILE 390


>UniRef50_Q7VR00 Tryptophan synthase beta chain n=5 Tax=Bacteria RepID=TRPB_BLOFL
          Length = 398

 Score =  573 bits (1476), Expect = e-162,   Method: Compositional matrix adjust.
 Identities = 268/391 (68%), Positives = 325/391 (83%)

Query: 1   MTTLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALT 60
           MT  L+ YFGEFGGMYVPQIL+PAL QLE+ F+ A KD  FQ  F +LL +YAGRPT LT
Sbjct: 1   MTQQLHSYFGEFGGMYVPQILIPALIQLEKEFIEAMKDISFQTTFKNLLHHYAGRPTPLT 60

Query: 61  KCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASA 120
            CQN+T+GT + LYLKREDLLHGG+HKTNQVLGQALLAKRM K EIIAETGAGQHGVA +
Sbjct: 61  LCQNLTSGTCSKLYLKREDLLHGGSHKTNQVLGQALLAKRMHKKEIIAETGAGQHGVAVS 120

Query: 121 LASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGS 180
           +AS+LL LKCRIYMG KD++RQ  NV RM+LMG +VIPVH GSATLKDACNEA+R+WS +
Sbjct: 121 IASSLLKLKCRIYMGYKDMKRQELNVLRMKLMGTQVIPVHHGSATLKDACNEAIREWSST 180

Query: 181 YETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGM 240
           Y+  HYM+GT AGPHP+PTIV+EFQR+IG ET  QI   E +LPDAVIAC+GGGSNAIG+
Sbjct: 181 YKHTHYMIGTVAGPHPFPTIVKEFQRIIGSETYNQIQTHEKKLPDAVIACIGGGSNAIGI 240

Query: 241 FADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSI 300
           F+ FI+  +V L+GVE GG G+ T  HG+ L+ G  GIYFGMK+P++Q+++GQI+ SYSI
Sbjct: 241 FSGFIDIPSVQLLGVEAGGLGLHTEYHGSSLQCGETGIYFGMKSPILQSQEGQIKNSYSI 300

Query: 301 SAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALK 360
           +AGLDFPSVGP+HAYL    R  YVSI D+EA+ AF+ L L+EGIIPALES+HALAHALK
Sbjct: 301 AAGLDFPSVGPEHAYLKKINRVKYVSINDEEAINAFQELSLYEGIIPALESAHALAHALK 360

Query: 361 MMRENPDKEQLLVVNLSGRGDKDIFTVHDIL 391
           ++R+ P K+Q+L+VNLSGRGDKDI TV++ L
Sbjct: 361 IIRKTPKKKQILIVNLSGRGDKDIITVNNAL 391


>UniRef50_C5V964 Tryptophan synthase, beta subunit n=2 Tax=Corynebacterium
           matruchotii RepID=C5V964_9CORY
          Length = 453

 Score =  498 bits (1283), Expect = e-139,   Method: Compositional matrix adjust.
 Identities = 238/392 (60%), Positives = 308/392 (78%), Gaps = 3/392 (0%)

Query: 3   TLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKC 62
           TL++ YFGE+GG YVP++L P+L QLE+A+V A  DPEF  + +DL +NY GRPT +T+C
Sbjct: 14  TLIDAYFGEYGGQYVPEVLYPSLDQLEQAYVDALNDPEFLRELDDLRRNYLGRPTPITEC 73

Query: 63  QNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALA 122
            N+    N  ++LKREDLLHGGAHK NQVL QALLAKRMGKT +IAETGAGQHG+A+A+ 
Sbjct: 74  ANLPLSGNARIFLKREDLLHGGAHKGNQVLAQALLAKRMGKTRLIAETGAGQHGMATAMV 133

Query: 123 SALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPV-HSGSATLKDACNEALRDWSGSY 181
           +AL+G++C IYMGA+DV RQ PNV+RMRLMGA+V+PV +     L DA + AL DW  S 
Sbjct: 134 AALMGMECTIYMGARDVARQQPNVYRMRLMGAKVVPVSNEHGEALSDAIDVALADWVESL 193

Query: 182 ETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMF 241
            T HY+LGTAAGPHP+P +V++FQ++I EE++ Q+LER GRLPDAV+ACVGGGSNAIG F
Sbjct: 194 GTTHYLLGTAAGPHPFPKLVKQFQKVISEESRQQMLERTGRLPDAVVACVGGGSNAIGAF 253

Query: 242 ADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSIS 301
           A+++ +  V LIGVEP G G+++G+HGAPL  G+VG+  G K+ +M   DG++  S+S+S
Sbjct: 254 AEYLPDEEVRLIGVEPAGEGLDSGKHGAPLNRGKVGVLHGSKSYVMLGSDGEVMHSHSVS 313

Query: 302 AGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKM 361
           AGLD+P VGP+HAYL  +GRA+YV ITD EAL+AF+ L  +EGIIPALESSHALA+ALK+
Sbjct: 314 AGLDYPGVGPEHAYLLDSGRAEYVGITDAEALQAFRMLSWYEGIIPALESSHALAYALKL 373

Query: 362 MRE-NPDKEQL-LVVNLSGRGDKDIFTVHDIL 391
               +P  E L ++VNLSGRGDKD+  V  IL
Sbjct: 374 AEHADPQGEPLNILVNLSGRGDKDVDYVRHIL 405


>UniRef50_P25269 Tryptophan synthase beta chain 2, chloroplastic n=1628 Tax=cellular
           organisms RepID=TRBP2_ARATH
          Length = 475

 Score =  440 bits (1132), Expect = e-122,   Method: Compositional matrix adjust.
 Identities = 216/384 (56%), Positives = 282/384 (73%), Gaps = 7/384 (1%)

Query: 9   FGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITA- 67
           FG+FGG YVP+ LM AL +LE AF S   D +FQ +  ++LK+Y GR + L   + +T  
Sbjct: 86  FGKFGGKYVPETLMHALSELETAFYSLATDEDFQRELAEILKDYVGRESPLYFAERLTEH 145

Query: 68  -----GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALA 122
                G    +YLKREDL H GAHK N  + QALLAKR+GK  IIAETGAGQHGVA+A  
Sbjct: 146 YRRENGEGPLIYLKREDLNHTGAHKINNAVAQALLAKRLGKKRIIAETGAGQHGVATATV 205

Query: 123 SALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYE 182
            A  GL+C IYMGA+D+ERQ+ NVFRMRL+GAEV  VHSG+ATLKDA +EA+RDW  + E
Sbjct: 206 CARFGLQCIIYMGAQDMERQALNVFRMRLLGAEVRGVHSGTATLKDATSEAIRDWVTNVE 265

Query: 183 TAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFA 242
           T HY+LG+ AGPHPYP +VR+F  +IG+ET+ Q +E+ G  PD ++ACVGGGSNA+G+F 
Sbjct: 266 TTHYILGSVAGPHPYPMMVRDFHAVIGKETRKQAMEKWGGKPDVLVACVGGGSNAMGLFH 325

Query: 243 DFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISA 302
           +F+++T V +IGVE  G G+++G+H A L  G VG+  G  + ++Q +DGQI E +SISA
Sbjct: 326 EFVDDTEVRMIGVEAAGFGLDSGKHAATLTKGDVGVLHGAMSYLLQDDDGQIIEPHSISA 385

Query: 303 GLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMM 362
           GLD+P VGP+H++L   GRA+Y S+TD+EALEAFK +   EGIIPALE+SHALAH  K+ 
Sbjct: 386 GLDYPGVGPEHSFLKDVGRAEYFSVTDEEALEAFKRVSRLEGIIPALETSHALAHLEKLC 445

Query: 363 RENPDKEQLLVVNLSGRGDKDIFT 386
              PD  + +V+N SGRGDKD+ T
Sbjct: 446 PTLPDGAR-VVLNFSGRGDKDVQT 468


>UniRef50_C9KJ78 Tryptophan synthase, beta subunit n=1 Tax=Mitsuokella multacida DSM
           20544 RepID=C9KJ78_9FIRM
          Length = 395

 Score =  434 bits (1115), Expect = e-120,   Method: Compositional matrix adjust.
 Identities = 217/386 (56%), Positives = 278/386 (72%), Gaps = 5/386 (1%)

Query: 9   FGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAG 68
           FG+FGG YVP+I+MPAL +LE A+   + DP+FQ +F   L+ YAGRPT L     +T  
Sbjct: 7   FGKFGGQYVPEIVMPALNELEAAYAKYKDDPDFQNEFKTYLREYAGRPTNLYYADKLTKY 66

Query: 69  T-NTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLG 127
                ++LKREDLLH GAHK N  LGQALLAKRMGK  I+AETGAGQHGVASA  +AL G
Sbjct: 67  YGRAKIFLKREDLLHTGAHKINNALGQALLAKRMGKKRIVAETGAGQHGVASATVAALFG 126

Query: 128 LKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYM 187
           ++C ++MGA DVERQ  NVFRM+L+GA+VIPV SG+ TLKDA +EA+R W+ +    HY+
Sbjct: 127 MECHVFMGALDVERQKLNVFRMKLLGAKVIPVSSGTGTLKDATSEAIRYWATNITDTHYI 186

Query: 188 LGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINE 247
           +G+A GPHPYPTIVR+FQ++IGEE + Q +E+ G LPD ++ACVGGGSNAIG F DF N+
Sbjct: 187 IGSAVGPHPYPTIVRDFQKVIGEEIREQAIEKIGGLPDYLLACVGGGSNAIGTFYDFRND 246

Query: 248 TNVGLIGVEPGGHGIETGEHGAPLK-HGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDF 306
            +V   GVE GG G    ++   L   G  GI  G  + ++Q  DGQ+ E+YSISAGLD+
Sbjct: 247 PSVKKFGVEAGGRGEAPTDNAKTLSGAGEPGILHGAFSYLLQDPDGQVVEAYSISAGLDY 306

Query: 307 PSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMM-REN 365
           P VGP+H+Y    G   YVS+TD EAL+AF+ L   EGIIPA+ESSHALA+  K+M + +
Sbjct: 307 PGVGPEHSYYKDEGIVKYVSVTDQEALDAFQRLSKVEGIIPAMESSHALAYLDKLMPQTH 366

Query: 366 PDKEQLLVVNLSGRGDKDIFTVHDIL 391
           PD+   +VV LSGRGDKD+  V  +L
Sbjct: 367 PDES--VVVTLSGRGDKDVQMVAKVL 390


>UniRef50_D2LTS0 Tryptophan synthase, beta subunit n=1 Tax=Bacillus cellulosilyticus
           DSM 2522 RepID=D2LTS0_BACS4
          Length = 611

 Score =  430 bits (1105), Expect = e-119,   Method: Compositional matrix adjust.
 Identities = 212/385 (55%), Positives = 270/385 (70%), Gaps = 2/385 (0%)

Query: 9   FGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAG 68
           FG+FGG YVP+ LM AL QLE AF  A +D  F A+ ++  + Y+GRPT LT  + ++  
Sbjct: 223 FGDFGGRYVPETLMYALEQLESAFDEAVQDEHFFAELHNEWEKYSGRPTPLTVAERLSKT 282

Query: 69  TN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLG 127
               ++YLKREDL H GAHK N  + QA+LAKRMGK +IIAETGAGQHGVA+A  +A  G
Sbjct: 283 LGGASIYLKREDLNHTGAHKINNAIAQAILAKRMGKQQIIAETGAGQHGVAAATVAARFG 342

Query: 128 LKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYM 187
           L C+++MG +D++RQ  NVFRM+L+GAEVI V SG  TLKDA NEA+R W        Y+
Sbjct: 343 LTCKVFMGEEDMKRQELNVFRMKLLGAEVIKVTSGGKTLKDATNEAIRHWVSHVNDTFYL 402

Query: 188 LGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINE 247
           +G+A GPHPYP +VREFQ +IG E++ Q L   G LPD VIACVGGGSNAIGMF  FIN+
Sbjct: 403 IGSAVGPHPYPKMVREFQSVIGRESRRQFLTETGALPDEVIACVGGGSNAIGMFYPFIND 462

Query: 248 TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFP 307
             V L GVE  G G++T EH A L  G  G+  G  + ++Q + G I E YSISAGLD+P
Sbjct: 463 EQVVLTGVEAAGKGVDTEEHAATLTKGVKGVLHGSLSYLLQDDFGNITEPYSISAGLDYP 522

Query: 308 SVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPD 367
            +GP+HAYL   GR  Y SITD EA+EA +TLC  EGI+PA+ES+HALA A K  +E  +
Sbjct: 523 GIGPEHAYLRDIGRVSYESITDKEAIEALQTLCQLEGILPAIESAHALAQAFKRAKELSE 582

Query: 368 KEQLLVVNLSGRGDKDIFTVHDILK 392
            + +LV  LSGRGDKD+ T+  +L+
Sbjct: 583 GKTILVC-LSGRGDKDVHTIQGVLE 606


>UniRef50_B1XY48 Tryptophan synthase beta chain n=287 Tax=cellular organisms
           RepID=TRPB_LEPCP
          Length = 428

 Score =  427 bits (1099), Expect = e-118,   Method: Compositional matrix adjust.
 Identities = 212/385 (55%), Positives = 278/385 (72%), Gaps = 4/385 (1%)

Query: 8   YFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITA 67
           +FG +GG +V + L  AL +L  A+   + DPEF A+F + L ++ GRP+ +     ++ 
Sbjct: 12  HFGIYGGSFVAETLSHALDELNAAYERYRHDPEFIAEFRNELAHFVGRPSPVYHAARMSR 71

Query: 68  GTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALL 126
                 +YLKREDL H GAHK N  +GQALLA+RMGK  +IAETGAGQHGVA+A   A  
Sbjct: 72  EVGGAQIYLKREDLNHTGAHKINNTIGQALLARRMGKPRVIAETGAGQHGVATATICARY 131

Query: 127 GLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHY 186
           G++C +YMG++DV+RQSPNV+RM L+GA V+PV SGS TLKDA NEA+RDW  + E   Y
Sbjct: 132 GMECVVYMGSEDVKRQSPNVYRMNLLGARVVPVESGSKTLKDALNEAMRDWVTNVENTFY 191

Query: 187 MLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFIN 246
           ++GT AGPHPYP +VR+FQR+IG+E   Q+    GR PDAV+ACVGGGSNA+G+F  +I 
Sbjct: 192 IIGTVAGPHPYPAMVRDFQRVIGDECLVQMPALAGRQPDAVVACVGGGSNAMGIFYPYIP 251

Query: 247 ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDF 306
              V LIGVE  G G+E+G+H A L+ G  G+  G +  ++Q  +GQI E++S+SAGLD+
Sbjct: 252 HEGVRLIGVEAAGEGMESGKHSASLQRGSPGVLHGNRTYVLQDANGQITETHSVSAGLDY 311

Query: 307 PSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRE-N 365
           P VGP+HAYL   GRA+YV ITD EAL+AF  LC  EGIIPALESSHA+A+A+K+ +   
Sbjct: 312 PGVGPEHAYLKDIGRAEYVGITDAEALQAFHYLCRAEGIIPALESSHAVAYAMKLAKTMR 371

Query: 366 PDKEQLLVVNLSGRGDKDIFTVHDI 390
           PD  Q ++VNLSGRGDKDI TV D+
Sbjct: 372 PD--QHVLVNLSGRGDKDIGTVADL 394


>UniRef50_A1KSW2 Tryptophan synthase beta chain n=49 Tax=Bacteria RepID=TRPB_NEIMF
          Length = 400

 Score =  426 bits (1095), Expect = e-118,   Method: Compositional matrix adjust.
 Identities = 208/382 (54%), Positives = 276/382 (72%), Gaps = 3/382 (0%)

Query: 8   YFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITA 67
           +FGE GG++V + L+PAL++L +A+ +A+ DPEF   F   LK+Y GRP+ +     ++ 
Sbjct: 12  FFGEHGGLFVSETLIPALQELADAYKAAKNDPEFWEAFRHDLKHYVGRPSPVYHAARLSE 71

Query: 68  GTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALL 126
                 ++LKREDL H GAHK N  +GQALLAKRMGK  +IAETGAGQHGVASA  +A  
Sbjct: 72  HLGGAQIWLKREDLNHTGAHKVNNTIGQALLAKRMGKKRVIAETGAGQHGVASATVAARF 131

Query: 127 GLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHY 186
           G+ C +YMGA D++RQ PNVFRM+L+GA V+ V SGS TLKDA NEA+R+W    +   Y
Sbjct: 132 GMTCDVYMGADDIQRQMPNVFRMKLLGANVVGVESGSRTLKDAMNEAMREWVARVDDTFY 191

Query: 187 MLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFIN 246
           ++GTAAGP PYP +VR+FQ +IG E KAQ+ E  GR PD  +ACVGGGSNAIG+F  +I 
Sbjct: 192 IIGTAAGPAPYPEMVRDFQCVIGNEAKAQMQEAIGRQPDVAVACVGGGSNAIGLFHPYIG 251

Query: 247 ETNVGLIGVEPGGHGIETGEHGAPLKHGR-VGIYFGMKAPMMQTEDGQIEESYSISAGLD 305
           E NV L+GVE GG G+ T +H AP+  G  +G+  G ++ +MQ E+GQ+  ++S+SAGLD
Sbjct: 252 EENVRLVGVEAGGLGVNTPDHAAPITSGAPIGVLHGFRSYLMQDENGQVLGTHSVSAGLD 311

Query: 306 FPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMREN 365
           +P +GP+H++L+   R +Y    DDEALEAF  LC  EGIIPALESSHA+A A+K   + 
Sbjct: 312 YPGIGPEHSHLHDIKRVEYTVAKDDEALEAFDLLCRFEGIIPALESSHAVAWAVKNAPKM 371

Query: 366 PDKEQLLVVNLSGRGDKDIFTV 387
             K+Q+++VNLSGRGDKDI TV
Sbjct: 372 -GKDQVILVNLSGRGDKDINTV 392


>UniRef50_A5UMB9 Tryptophan synthase, beta subunit, TrpB n=5 Tax=cellular organisms
           RepID=A5UMB9_METS3
          Length = 593

 Score =  422 bits (1085), Expect = e-116,   Method: Compositional matrix adjust.
 Identities = 212/391 (54%), Positives = 282/391 (72%), Gaps = 5/391 (1%)

Query: 6   NPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNI 65
           N  +GE+GG Y+ + LM  L  LEE +     D EF  + N LLK YAGRP+ L   + +
Sbjct: 202 NGRYGEYGGQYISETLMNELIYLEEQYYHYMNDSEFVEELNTLLKEYAGRPSLLYYAKRM 261

Query: 66  TAGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASA 124
           T       +YLKREDL H GAHK N VLGQ LLAK+MGKT +IAETGAGQHGVA+A A+A
Sbjct: 262 TEDLGGAKIYLKREDLNHTGAHKINNVLGQVLLAKKMGKTRVIAETGAGQHGVATATAAA 321

Query: 125 LLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETA 184
           LL ++C +YMG  D +RQ+ NV+RM L+GA+V PV SG+ TLKDA N+A RDW G     
Sbjct: 322 LLDMECEVYMGELDTKRQALNVYRMELLGAKVHPVKSGTKTLKDAVNDAFRDWIGRVHDT 381

Query: 185 HYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADF 244
           +Y++G+  GPHP+P +VR+FQ +I  E + Q LE+EG+LPDAV+ACVGGGSNA+G F +F
Sbjct: 382 NYVIGSTMGPHPFPMMVRDFQAVISAEAREQFLEKEGKLPDAVLACVGGGSNAMGAFYNF 441

Query: 245 INETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGL 304
           I++ +V LIG E GG G++T  + A L +G++GI+ GMK+   Q E GQI E YS+SAGL
Sbjct: 442 IDDADVKLIGCEAGGKGVDTPYNAAALTNGQIGIFHGMKSIFNQGEYGQISEVYSVSAGL 501

Query: 305 DFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRE 364
           D+P VGP+HAYL    RA+YV +TD+EA+ AF+ L   EGIIPA+ES+HA+AHA+K+  +
Sbjct: 502 DYPGVGPEHAYLRDIKRAEYVPVTDEEAVNAFEYLSKMEGIIPAIESAHAVAHAMKIAPK 561

Query: 365 NPDKEQLLVVNLSGRGDKDIFTVHDILKARG 395
             DK+++++V LSGRGDKD+ +   I K RG
Sbjct: 562 -MDKDEIIMVCLSGRGDKDVAS---IAKYRG 588


>UniRef50_B7FQI2 Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1
           RepID=B7FQI2_PHATR
          Length = 671

 Score =  421 bits (1083), Expect = e-116,   Method: Compositional matrix adjust.
 Identities = 205/389 (52%), Positives = 275/389 (70%), Gaps = 5/389 (1%)

Query: 6   NPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNI 65
           N  FG+FGG Y+P+ L  A  ++E ++   + DP F A+ ++  +++ G PT L +   +
Sbjct: 281 NSRFGKFGGQYIPETLSVAFEEIEASYNELKDDPSFLAELDEYRRDFVGGPTPLHRADRL 340

Query: 66  TA-GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASA 124
           T      T++LKREDL H GAHK N  +GQALLAKR+GK  IIAETGAGQHGVA+A   A
Sbjct: 341 TELAGGATIWLKREDLAHTGAHKINNAIGQALLAKRIGKPRIIAETGAGQHGVATATICA 400

Query: 125 LLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETA 184
            LGL C +YMGA D ERQ  NVFRM  +GA+V+PV  G  TLKDA NEA+RDW  +    
Sbjct: 401 KLGLDCTVYMGAVDCERQKLNVFRMNTLGAKVVPVQDGQRTLKDAINEAMRDWVTNVRDT 460

Query: 185 HYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADF 244
           HY++G+A GPHP+PTIVR+FQ ++G E +AQ+LER G+LPDAV+ACVGGGSNAIG F  F
Sbjct: 461 HYLIGSAVGPHPFPTIVRDFQSVMGREMRAQMLERAGKLPDAVVACVGGGSNAIGAFHPF 520

Query: 245 INETNVGLIGVEPGGHGIETG-EHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAG 303
           +N+  V L GVE  G+GI+   EH A L  G  G+  G    ++Q + GQ   ++SISAG
Sbjct: 521 VNDETVELHGVEAAGYGIDKDEEHCATLTKGTPGVLQGAMTYVIQQKSGQTLNTHSISAG 580

Query: 304 LDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMR 363
           LD+P VGP+HA+L  +GRA Y ++TDDEALE FK +C +EGIIPALE+SHA+ +A+K+ +
Sbjct: 581 LDYPGVGPEHAFLKDSGRAVYEAVTDDEALEGFKLMCEYEGIIPALETSHAIYYAVKLAK 640

Query: 364 E-NPDKEQLLVVNLSGRGDKDIFTVHDIL 391
           +  P K+  +V+N+SGRGDKD+  +  I+
Sbjct: 641 KLGPGKD--IVINMSGRGDKDMPQIAKIM 667


>UniRef50_P00931 Tryptophan synthase n=45 Tax=Eukaryota RepID=TRP_YEAST
          Length = 707

 Score =  413 bits (1061), Expect = e-114,   Method: Compositional matrix adjust.
 Identities = 206/390 (52%), Positives = 277/390 (71%), Gaps = 6/390 (1%)

Query: 9   FGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAG 68
           FG+FGG YVP+ L   LR+LE+ F  A  DP F   F  L  +Y GRP++L K + +T  
Sbjct: 306 FGDFGGQYVPEALHACLRELEKGFDEAVADPTFWEDFKSLY-SYIGRPSSLHKAERLTEH 364

Query: 69  TN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLG 127
                ++LKREDL H G+HK N  L Q LLAKR+GK  +IAETGAGQHGVA+A A A  G
Sbjct: 365 CQGAQIWLKREDLNHTGSHKINNALAQVLLAKRLGKKNVIAETGAGQHGVATATACAKFG 424

Query: 128 LKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYM 187
           L C ++MGA+DV RQ+ NVFRMR++GA+VI V +G+ TL+DA +EA R W  + +T +Y+
Sbjct: 425 LTCTVFMGAEDVRRQALNVFRMRILGAKVIAVTNGTKTLRDATSEAFRFWVTNLKTTYYV 484

Query: 188 LGTAAGPHPYPTIVREFQRMIGEETKAQILE-REGRLPDAVIACVGGGSNAIGMFADFIN 246
           +G+A GPHPYPT+VR FQ +IG+ETK Q      G+LPDAV+ACVGGGSN+ GMF+ F +
Sbjct: 485 VGSAIGPHPYPTLVRTFQSVIGKETKEQFAAMNNGKLPDAVVACVGGGSNSTGMFSPFEH 544

Query: 247 ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDF 306
           +T+V L+GVE GG G++T  H A L  GR G++ G+K  ++Q  DGQ+ +++S+SAGLD+
Sbjct: 545 DTSVKLLGVEAGGDGVDTKFHSATLTAGRPGVFHGVKTYVLQDSDGQVHDTHSVSAGLDY 604

Query: 307 PSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRE-N 365
           P VGP+ AY  STGRA +++ TD +AL  FK L   EGIIPALESSHA+  A ++ +   
Sbjct: 605 PGVGPELAYWKSTGRAQFIAATDAQALLGFKLLSQLEGIIPALESSHAVYGACELAKTMK 664

Query: 366 PDKEQLLVVNLSGRGDKDIFTVHDILKARG 395
           PD  Q LV+N+SGRGDKD+ +V ++L   G
Sbjct: 665 PD--QHLVINISGRGDKDVQSVAEVLPKLG 692


>UniRef50_Q2S700 Tryptophan synthase, beta subunit n=6 Tax=Bacteria
           RepID=Q2S700_HAHCH
          Length = 426

 Score =  405 bits (1040), Expect = e-111,   Method: Compositional matrix adjust.
 Identities = 207/385 (53%), Positives = 265/385 (68%), Gaps = 4/385 (1%)

Query: 6   NPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNI 65
           N  FG FGG Y P+IL PAL +LE  F S + DP+F  ++  L + ++GRPT LT C+ +
Sbjct: 6   NGMFGSFGGRYAPEILTPALIELERLFFSLRDDPDFWREYQTLAQQFSGRPTPLTPCERL 65

Query: 66  TAGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASA 124
           +       ++LKREDL H GAHK N VLGQ LL +RMGK  +IAETGAGQHG+A+A+ +A
Sbjct: 66  SREIGGAQIWLKREDLNHSGAHKVNNVLGQGLLVRRMGKRRVIAETGAGQHGLATAIMAA 125

Query: 125 LLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETA 184
            LGL+CRIYMG  D+ERQ  NVF MR +GAEVIPV +G+ TLK+A +EALRDW+ S+E  
Sbjct: 126 RLGLECRIYMGEDDIERQYGNVFWMRRLGAEVIPVATGARTLKEAMDEALRDWAASFEDT 185

Query: 185 HYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADF 244
           HY+LGTA GP P+P +V  FQ +IG+E + Q L + GR PD+V+ACVGGGSNA+G FA F
Sbjct: 186 HYVLGTACGPAPFPELVAYFQSIIGKELQQQALSQIGRNPDSVVACVGGGSNALGAFAPF 245

Query: 245 INETNVGLIGVEPGGHGIETGEHGAPLKH--GRVGIYFGMKAPMMQTEDGQIEESYSISA 302
           I   +V L+GVE GG   E G+H   L+   G  GI  G K   +Q  DGQ+  ++S++A
Sbjct: 246 IERHDVELVGVEAGGRSREEGQHSIRLQEGTGEDGIAQGFKTLFLQDADGQLGHTHSVAA 305

Query: 303 GLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMM 362
           GLD+  V P  A L   GR    S TD+EAL AF+TL  +EGIIPALESSHALA   +  
Sbjct: 306 GLDYVGVSPILADLTQRGRLTPDSATDEEALAAFETLLRYEGIIPALESSHALAGGFRRA 365

Query: 363 RENPDKEQLLVVNLSGRGDKDIFTV 387
            +    +Q +V+NLSGRGDKDIF V
Sbjct: 366 AQM-SPQQHMVINLSGRGDKDIFNV 389


>UniRef50_D1HPU5 Whole genome shotgun sequence of line PN40024,
           scaffold_116.assembly12x (Fragment) n=2 Tax=Vitis
           vinifera RepID=D1HPU5_VITVI
          Length = 407

 Score =  387 bits (995), Expect = e-106,   Method: Compositional matrix adjust.
 Identities = 195/385 (50%), Positives = 262/385 (68%), Gaps = 10/385 (2%)

Query: 9   FGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNIT-- 66
           FG FGG +VP+ LM  L +LE  F     DPEFQ +    L++Y GR T L   Q +T  
Sbjct: 8   FGRFGGKFVPETLMTCLSKLEAEFNLVLHDPEFQEELATALRDYVGRETPLYFAQRLTDH 67

Query: 67  ----AGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALA 122
               +G    +YLKREDL HGGAHK N  + QA++AKRMG+T I+A TGAGQHGVA+A A
Sbjct: 68  YKNESGCGPEIYLKREDLNHGGAHKINNAIAQAMIAKRMGRTSIVAATGAGQHGVATAAA 127

Query: 123 SALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYE 182
            A L LKC I MG  D+ERQ+ NV  M+L+GAEV  V       K+A +EA+R+W G+ E
Sbjct: 128 CAKLSLKCTIVMGTLDMERQASNVLLMKLLGAEVKSV---DGNFKNATSEAIREWVGNLE 184

Query: 183 TAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFA 242
           T ++++GTA GPHP P++VREFQ +IG+ET+ Q +ER GR PD ++ACVG GSNA+G+F 
Sbjct: 185 TNYFLIGTAVGPHPCPSMVREFQSIIGKETRRQAMERWGRKPDVLVACVGSGSNALGLFH 244

Query: 243 DFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISA 302
           +FI + +V +IGVE  G G+E+G+H A L  G VG+Y G  + ++Q E+GQI   +SI  
Sbjct: 245 EFIADEDVRMIGVEAAGFGLESGKHSATLAKGEVGVYHGAMSYLLQDEEGQIVGPHSIGV 304

Query: 303 GLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMM 362
           G+++P V P+ ++L  TGR +  S+TD EA++A++ LC  EGI PALE+SHALA   K+ 
Sbjct: 305 GMEYPGVSPELSFLKETGRVESYSVTDQEAVDAYQLLCRLEGIFPALEASHALAFLDKLC 364

Query: 363 RENPDKEQLLVVNLSGRGDKDIFTV 387
              PD  + +VVN SGRGDKD  TV
Sbjct: 365 PTLPDGGK-VVVNCSGRGDKDAPTV 388


>UniRef50_Q0RGR3 Tryptophan synthase, beta protein n=2 Tax=Actinomycetales
           RepID=Q0RGR3_FRAAA
          Length = 487

 Score =  383 bits (984), Expect = e-105,   Method: Compositional matrix adjust.
 Identities = 201/379 (53%), Positives = 255/379 (67%), Gaps = 15/379 (3%)

Query: 9   FGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAG 68
           FGEFGG YVP+ L+ A   LE A+  A+ DP F  Q + LL  YAGRPT +T    ++  
Sbjct: 112 FGEFGGRYVPEALVSACEDLEAAYRDARSDPSFTQQLDHLLSVYAGRPTPVTPANRLSEE 171

Query: 69  TNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGL 128
               L LKREDL H G+HK N VLGQ LLA+RMGK  ++AETGAGQHGVA+A   ALLGL
Sbjct: 172 LGVHLLLKREDLAHTGSHKINNVLGQGLLAQRMGKKRLLAETGAGQHGVATATIGALLGL 231

Query: 129 KCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYML 188
              +YMG  D++RQ+ NVFRM L+GA V+PV SG+ TLKDAC+EALR W    + AHY +
Sbjct: 232 DVVVYMGEADIQRQALNVFRMELLGATVVPVTSGTRTLKDACSEALRQWVTQVDEAHYCI 291

Query: 189 GTAAGPHPYPTIVREFQRMIGEETKAQI--LEREGRLPDAVIACVGGGSNAIGMFADFIN 246
           G+  GPHPYP +VREFQR+IG E +AQ   L R+G +PD V ACVGGGSNA G FA F++
Sbjct: 292 GSTMGPHPYPWMVREFQRVIGTEARAQCAGLLRQG-VPDVVTACVGGGSNAAGTFAGFVD 350

Query: 247 ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDF 306
            T   L+GVE  G        GA +  G  GI  G  + ++Q EDGQ+ E++SISAGLD+
Sbjct: 351 -TPARLVGVEAAG--------GAAMTDGLPGILHGFYSNILQDEDGQVREAHSISAGLDY 401

Query: 307 PSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMR--E 364
           P +GP+HA L ++GRA+YV+  D+E + A   L   EGI+PALES+HALA  ++     E
Sbjct: 402 PGIGPEHAGLGTSGRAEYVTANDEEVVSAVVRLARAEGILPALESAHALAWIIRAAESGE 461

Query: 365 NPDKEQLLVVNLSGRGDKD 383
            P    +L + LSGRGDKD
Sbjct: 462 IPYGSTVL-MTLSGRGDKD 479


>UniRef50_Q822W9 Tryptophan synthase beta chain 1 n=8 Tax=Bacteria RepID=TRPB1_CHLCV
          Length = 412

 Score =  382 bits (980), Expect = e-104,   Method: Compositional matrix adjust.
 Identities = 203/384 (52%), Positives = 272/384 (70%), Gaps = 2/384 (0%)

Query: 12  FGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTN- 70
           +GG YVP  L+  L  L+ ++   +KDP+F+  F+ +LKNYAGRPT LT+ +N +   N 
Sbjct: 27  YGGQYVPLELVKPLEDLDRSYEQLKKDPQFRETFHHILKNYAGRPTPLTEVKNFSRAING 86

Query: 71  TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKC 130
             ++LKREDLLH GAHK N VLGQ L+AK  GKT ++AETGAGQHGVA A A+A LG++C
Sbjct: 87  PRIFLKREDLLHTGAHKINNVLGQCLIAKFQGKTRVVAETGAGQHGVALAAAAAYLGMEC 146

Query: 131 RIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGT 190
            I+MG  D+ RQ PNV R+R++GAEV+ V  G++ LK+A + A+ D+   ++  H+ +G+
Sbjct: 147 VIFMGETDINRQKPNVDRIRVLGAEVVSVKRGNSGLKEAVDAAIEDFIFKHDHTHFCIGS 206

Query: 191 AAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNV 250
           A GP+PYP IVR+FQ +I  E K+QI E   R PD +IACVGGGSNAIG F  FI  T V
Sbjct: 207 ALGPYPYPKIVRDFQSVISLEVKSQIKEYTDRDPDILIACVGGGSNAIGFFHHFIPNTKV 266

Query: 251 GLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVG 310
            L+GVE GG G+E+G+H A    G+ G+  G  + ++Q EDG   ++YSISAGLD+ SVG
Sbjct: 267 KLVGVEGGGLGVESGKHAARFATGKPGVVHGFHSYVLQDEDGNCADTYSISAGLDYVSVG 326

Query: 311 PQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQ 370
           P HA ++ +GRA Y   TDDEALEAF+ L   EGIIPALESSHALAH +K+   + DK+ 
Sbjct: 327 PTHAEMHESGRAQYTYATDDEALEAFRLLSKTEGIIPALESSHALAHMIKIA-PSLDKDT 385

Query: 371 LLVVNLSGRGDKDIFTVHDILKAR 394
           + +VNLSGRGDKD+  + D+ K +
Sbjct: 386 IAIVNLSGRGDKDLSQIIDLDKRK 409


>UniRef50_Q7VGA7 Tryptophan synthase beta chain n=4 Tax=Proteobacteria
           RepID=TRPB_HELHP
          Length = 420

 Score =  374 bits (960), Expect = e-102,   Method: Compositional matrix adjust.
 Identities = 192/389 (49%), Positives = 254/389 (65%), Gaps = 11/389 (2%)

Query: 6   NPYFGE-------FGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTA 58
           N YFGE       FGG Y+P+IL+PAL++LE+A+        ++ +   L K++ GRPT 
Sbjct: 11  NGYFGEAKGGNHAFGGQYIPEILLPALKELEKAYHGVFVSKAYKKELKSLFKHFVGRPTP 70

Query: 59  LTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVA 118
           L    N +      +YLK E L + GAHK N  LGQ LLAK M K  +IAETGAGQHG+A
Sbjct: 71  LIYAHNASKILKNDIYLKFEGLANTGAHKINNALGQVLLAKHMKKKRVIAETGAGQHGLA 130

Query: 119 SALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWS 178
           +A A A LGL+C I+MG  D+ RQ PNVF M L GA+V  V SGS TLKDA NEALR+WS
Sbjct: 131 TAAACARLGLECEIFMGEIDIARQRPNVFNMELFGAKVHSVSSGSKTLKDAVNEALREWS 190

Query: 179 GSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAI 238
              + + Y+LG+A GP+PYP IVR+ Q +I +E K Q       LPD ++ACVGGGSNA+
Sbjct: 191 KRSDDSFYVLGSALGPYPYPDIVRDLQSVISKELKKQTKAYFSSLPDILVACVGGGSNAM 250

Query: 239 GMFADFINETNVGLIGVEPGGHGIETGEHGAPLK--HGRVGIYFGMKAPMMQTEDGQIEE 296
           G F  ++ E  V LIGVE GG G + GE+   +   +   GI  G K+  +Q +DGQ+ +
Sbjct: 251 GFFTHYLKEERVRLIGVEAGGIGDKEGENAIRINTINASEGIAQGYKSLFLQDKDGQLSD 310

Query: 297 SYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALA 356
           ++SISAGLD+  +GPQ A+L   GR ++ S TD EALEA      +EGIIPALESSHALA
Sbjct: 311 THSISAGLDYAGIGPQLAHLYEVGRVEFQSATDKEALEALSFFAQYEGIIPALESSHALA 370

Query: 357 HALKMMRENPDKEQLLVVNLSGRGDKDIF 385
             +++ ++   K+  ++ N+SGRGDKDIF
Sbjct: 371 AVIRLCKDIKGKK--IIANISGRGDKDIF 397


>UniRef50_D2VKV7 Predicted protein n=1 Tax=Naegleria gruberi RepID=D2VKV7_NAEGR
          Length = 434

 Score =  373 bits (958), Expect = e-102,   Method: Compositional matrix adjust.
 Identities = 197/395 (49%), Positives = 266/395 (67%), Gaps = 18/395 (4%)

Query: 11  EFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITA--G 68
           +FGG +VP  L   L +L + F+  + D EF  +F DLL+++ GRPT L+  +N     G
Sbjct: 44  QFGGCHVPPQLQKVLERLRDEFLKYKDDEEFNKEFRDLLRDFVGRPTPLSPARNFAKQLG 103

Query: 69  TNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLG- 127
           TN  +YLKRED  H G+HK N  +GQ LLAKRMG   IIAETGAGQHG A A   AL G 
Sbjct: 104 TNAKIYLKREDTAHLGSHKINNCIGQILLAKRMGAKRIIAETGAGQHGSAVAAVCALFGN 163

Query: 128 LKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYM 187
           ++C IYMGA+D  RQS NVFRM+++GA+VIPV  G   L+DA +EAL D   +YE   Y+
Sbjct: 164 IECVIYMGAEDCRRQSLNVFRMQMLGAKVIPVTKGQGRLRDAVDEALGDLVQNYENTFYL 223

Query: 188 LGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFIN- 246
           LG+A GP P+P +V+ FQ +I EE++ QIL+ E +LP  VIACVGGGSNAIG F+ ++  
Sbjct: 224 LGSAVGPCPFPNMVKHFQSVISEESRQQILQAENKLPTMVIACVGGGSNAIGAFSHYLRK 283

Query: 247 --ETNVGLIGVEPGGHGIETGEHGAP-LKHGRVGIYFGMKAPMMQTEDGQIEESYSISAG 303
             +  V L+G+EP    IE     AP L  G   I  G K+  +  E+G+ +++YS++AG
Sbjct: 284 GEDEKVRLLGIEP----IE-----APTLTEGVPYILHGFKSLCLLDENGEPKKTYSVAAG 334

Query: 304 LDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMR 363
           LD+PSVG  H+YL S GR +Y +++  + LEAF  L   EGIIPALESSHALA+ ++M +
Sbjct: 335 LDYPSVGSIHSYLKSIGRCEYYTVSKKQVLEAFMLLSKSEGIIPALESSHALAYVVEMAK 394

Query: 364 ENPDK-EQLLVVNLSGRGDKDIFTVHDILKARGEI 397
            N  K + ++VVNLSGRGDKD+  V+D++K +GE 
Sbjct: 395 NNQLKDDDIVVVNLSGRGDKDVEQVYDMIK-KGEF 428


>UniRef50_B2TM49 Tryptophan synthase beta chain n=40 Tax=cellular organisms
           RepID=TRPB_CLOBB
          Length = 405

 Score =  369 bits (947), Expect = e-100,   Method: Compositional matrix adjust.
 Identities = 184/380 (48%), Positives = 259/380 (68%), Gaps = 4/380 (1%)

Query: 6   NPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNI 65
           N  FG++GG Y+   L+PA  ++ +A+ +     +F  +   + K + GRPT +  C+ +
Sbjct: 14  NGRFGQYGGAYLTAELIPAFEEIADAYQTICHSSQFINELRRIRKEFQGRPTPVYHCERL 73

Query: 66  T-AGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASA 124
           + A  N  +YLKREDL H GAHK N  +G+ LLAK MGK  +IAETGAGQHGVA A A+A
Sbjct: 74  SRAIGNCQIYLKREDLNHTGAHKLNHCMGEGLLAKFMGKKRLIAETGAGQHGVALATAAA 133

Query: 125 LLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETA 184
             GL+C I+MG  D+ +Q+PNV RM+++GA+V+PV  G  TLK+A + A   ++ +Y+ +
Sbjct: 134 FFGLECEIHMGEVDIAKQAPNVTRMKILGAKVVPVTHGLKTLKEAVDSAFDSYAKNYKDS 193

Query: 185 HYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADF 244
            Y +G+A GPHP+P +VR+FQ ++G E K Q  E  G LPD V ACVGGGSNA GMF  F
Sbjct: 194 IYCIGSALGPHPFPLMVRDFQAVVGYEAKDQFKEMTGFLPDVVTACVGGGSNAAGMFIPF 253

Query: 245 INETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGL 304
           + E  V +IG+EP G G + G+H A +K+G  G+  G ++ M++ ++G     YSI++GL
Sbjct: 254 LEEP-VDIIGIEPLGRGEKLGDHAASMKYGEKGVMHGFESIMLKDKNGDPAPVYSIASGL 312

Query: 305 DFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRE 364
           D+PSVGP+HA+L   GR DY  I D+EA+EAF  L  +EGIIPA+ESSHA+A+A+K   E
Sbjct: 313 DYPSVGPEHAFLRELGRVDYKVINDEEAMEAFFKLSRYEGIIPAIESSHAVAYAMKKAEE 372

Query: 365 NPDKEQLLVVNLSGRGDKDI 384
              K+  ++V LSGRGDKDI
Sbjct: 373 M--KQGSILVCLSGRGDKDI 390


>UniRef50_C0NSJ2 Bifunctional tryptophan synthase TRPB n=1 Tax=Ajellomyces
           capsulatus G186AR RepID=C0NSJ2_AJECG
          Length = 594

 Score =  368 bits (944), Expect = e-100,   Method: Compositional matrix adjust.
 Identities = 189/383 (49%), Positives = 247/383 (64%), Gaps = 47/383 (12%)

Query: 9   FGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAG 68
           FGEFGG YVP+ LM  L +LE                                       
Sbjct: 246 FGEFGGQYVPESLMDNLLELE--------------------------------------- 266

Query: 69  TNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGL 128
                   REDL H G+HK N  LGQ LLA+R+GKT IIAETGAGQHGVA+A   A  G+
Sbjct: 267 -------AREDLNHTGSHKINNALGQVLLARRLGKTRIIAETGAGQHGVATATVCAKFGM 319

Query: 129 KCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYML 188
           +C IYMGA+DV RQ+ NVFR++L+GA+V+ V +GS TL+DA NEALR W    +T HY++
Sbjct: 320 ECVIYMGAEDVRRQALNVFRIKLLGAKVVAVEAGSRTLRDAVNEALRAWVVHLDTTHYVI 379

Query: 189 GTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINET 248
           G+A GPHP+PTIVR  Q +IGEETK Q+ +  GRLPDAV+ACVGGGSNA+GMF  F  + 
Sbjct: 380 GSAIGPHPFPTIVRTLQSVIGEETKEQMQKLTGRLPDAVVACVGGGSNAVGMFYPFTKDP 439

Query: 249 NVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPS 308
           +V L+GVE GG G +T  H A L HG  G+  G++  ++Q EDGQI +++SISAGLD+P 
Sbjct: 440 SVRLLGVEAGGDGTDTARHSATLSHGSKGVLHGVRTYILQNEDGQIADTHSISAGLDYPG 499

Query: 309 VGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDK 368
           VGP+ +      RA +++ TD +AL+ F+ +   EGIIPALESSHA+  A+++ +     
Sbjct: 500 VGPELSSWKDQSRAQFIAATDAQALQGFRLITELEGIIPALESSHAVFGAVELAKTMKKG 559

Query: 369 EQLLVVNLSGRGDKDIFTVHDIL 391
           E  +V+NLSGRGDKD+ +V D L
Sbjct: 560 EN-IVLNLSGRGDKDVQSVADAL 581


>UniRef50_B2KCI5 Tryptophan synthase beta chain n=2 Tax=Bacteria RepID=TRPB_ELUMP
          Length = 412

 Score =  367 bits (943), Expect = e-100,   Method: Compositional matrix adjust.
 Identities = 187/377 (49%), Positives = 262/377 (69%), Gaps = 2/377 (0%)

Query: 8   YFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITA 67
           ++G +GG++VP+ L+  L ++ + F +     EFQ +     KNY GRP+ L    NI+ 
Sbjct: 23  FYGIYGGVFVPKELIVPLAEIADCFNNTAFTKEFQDELFYYYKNYVGRPSPLYYAANISC 82

Query: 68  GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLG 127
           G    +YLKREDL H GAHK N  +G+ LLAK+MGK  +IAETGAGQHG+A A A+ALLG
Sbjct: 83  G-GAKIYLKREDLNHTGAHKINHCIGEVLLAKKMGKKRVIAETGAGQHGIAIATAAALLG 141

Query: 128 LKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYM 187
           ++C IYMG +DV+++ PNV +++ +GA+V+ V SG+  LK+A + A  D+    ET  Y 
Sbjct: 142 IECVIYMGEQDVKKEYPNVLKIKTLGAKVVCVGSGAKGLKEAVDAAFDDYLKDPETQMYA 201

Query: 188 LGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINE 247
           +G+  GPHP+P +V  FQ ++G+E + Q LE+EGRLPD V+ACVGGGSN++G+F+ F  +
Sbjct: 202 IGSVVGPHPFPLMVASFQSIVGKEAREQFLEQEGRLPDNVVACVGGGSNSMGIFSGFFAD 261

Query: 248 TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFP 307
             V L GVEP G G+ETG H APL  GRVG+  G K   MQ + G    ++S+++GLD+ 
Sbjct: 262 KTVKLTGVEPAGKGLETGLHAAPLAKGRVGVVHGFKCYFMQDDKGNPMGTHSVASGLDYL 321

Query: 308 SVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPD 367
            VGPQH YL  +GR  Y S  DDEA++AF  L   EGIIPALES+HA+A+ALK+ +E   
Sbjct: 322 GVGPQHCYLKDSGRVTYRSACDDEAVDAFFMLSRKEGIIPALESAHAVAYALKLSKE-LG 380

Query: 368 KEQLLVVNLSGRGDKDI 384
           K++ ++VNLSGRG+KD+
Sbjct: 381 KDKSILVNLSGRGEKDL 397


>UniRef50_D0JB95 Bifunctional phosphoribosylanthranilate isomerase/tryptophan
           synthase subunit beta n=1 Tax=Blattabacterium sp.
           (Blattella germanica) str. Bge RepID=D0JB95_BLASB
          Length = 610

 Score =  367 bits (942), Expect = e-100,   Method: Compositional matrix adjust.
 Identities = 192/386 (49%), Positives = 259/386 (67%), Gaps = 8/386 (2%)

Query: 6   NPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNI 65
           N Y+GEFGG ++P++L   + +L++ +       EFQ  +  +LKNYAGRPT L  C+  
Sbjct: 218 NGYYGEFGGAFIPEMLHHNITELQDQYKKFITSFEFQKLYKKILKNYAGRPTPLFFCKKY 277

Query: 66  TAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASAL 125
           +      +YLKREDL H G+HK N  +GQALLAK++GK +IIAETGAGQHGVA+A   AL
Sbjct: 278 SDKYKAKIYLKREDLNHTGSHKINNSIGQALLAKQLGKKKIIAETGAGQHGVATATTCAL 337

Query: 126 LGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAH 185
           + L+C I+MG  D+ RQ  NV RM+ +GA+VIPV SG  TLKDA NEA+R W  S+  ++
Sbjct: 338 MNLECIIFMGETDIHRQYTNVLRMKSLGAKVIPVCSGDKTLKDAVNEAIRYWI-SHPESY 396

Query: 186 YMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREG-RLPDAVIACVGGGSNAIGMFADF 244
           Y++G+  GPHPYP +V + Q +I EE K Q+ E+EG   P+ V+AC+GGGSNA G F  F
Sbjct: 397 YLIGSTVGPHPYPQMVADIQSIISEEIKIQLKEKEGSSFPNYVVACIGGGSNAAGSFYHF 456

Query: 245 INETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGL 304
           ++  +V L+ VE  G G+ T +  A +  G  GI  G    ++Q EDGQ+  ++SISAGL
Sbjct: 457 LDNDSVNLVAVEAAGLGVNTKKTAASIHCGSRGILHGSMTMLLQNEDGQVLPAHSISAGL 516

Query: 305 DFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRE 364
           D+P +GP  A L    R +++  TD+EAL+A   L   EGIIPALESSHALA ALK +  
Sbjct: 517 DYPGIGPMFANLFVKKRVNFLHSTDEEALQAGYELTRLEGIIPALESSHALA-ALKNI-- 573

Query: 365 NPDKE-QLLVVNLSGRGDKDIFTVHD 389
            P K+  ++VV LSGRGDKDI  V+D
Sbjct: 574 -PFKKMDVVVVTLSGRGDKDI-NVYD 597


>UniRef50_A8Z5Y3 Putative tryptophan synthase, beta subunit (TrpB)/anthranilate
           isomerase activity of trpC (TrpF) n=1 Tax=Candidatus
           Sulcia muelleri GWSS RepID=A8Z5Y3_SULMW
          Length = 595

 Score =  367 bits (941), Expect = e-100,   Method: Compositional matrix adjust.
 Identities = 183/379 (48%), Positives = 252/379 (66%), Gaps = 8/379 (2%)

Query: 8   YFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITA 67
           ++G FGG Y+P++L   +  L+  +     +  F+ +   LL NY GRP+ L  C N++ 
Sbjct: 216 FYGNFGGAYIPEMLYNNINHLKNEYNKIINNNCFKKKLKRLLHNYVGRPSPLFYCNNLSK 275

Query: 68  GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLG 127
                +YLKREDL H G+HK N  +GQALLAK +GK  II+ETGAGQHGVA++   +LLG
Sbjct: 276 IYGAKIYLKREDLNHTGSHKINNTIGQALLAKEIGKKNIISETGAGQHGVATSTICSLLG 335

Query: 128 LKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYM 187
           LKC I+MG  D++RQ  NV+RM+++GA +I V+SGS TLKD+ NEA+R W  +    +YM
Sbjct: 336 LKCTIFMGEVDIKRQIQNVYRMKMLGANIIAVNSGSKTLKDSVNEAIRYWINN-PDCYYM 394

Query: 188 LGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINE 247
           +G+A GP PYP +V  FQ +I EE K Q+ E    LP+ +IAC+GGGSNA G+F  F+++
Sbjct: 395 IGSAVGPDPYPRMVSYFQSIISEEIKEQLKE----LPNYIIACLGGGSNAAGIFYHFLDD 450

Query: 248 TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFP 307
             V LIGVE  G G+ T +  A ++ G  G+  G    +MQ + GQI E YSISAGLD+P
Sbjct: 451 EYVKLIGVEASGLGLNTNKTAATIQKGSRGVLHGSMTILMQDKYGQILEPYSISAGLDYP 510

Query: 308 SVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPD 367
            +GP HA L    RA ++S+TD EA+EA   L   EGIIPALES+HA+A   K+  +   
Sbjct: 511 GIGPMHANLFYKNRATFISVTDFEAIEAGIELSSLEGIIPALESAHAIASLKKLSFK--- 567

Query: 368 KEQLLVVNLSGRGDKDIFT 386
           K  L+++N+SGRGDKD+ T
Sbjct: 568 KNDLVIINMSGRGDKDMDT 586


>UniRef50_B0R332 Tryptophan synthase beta chain n=8 Tax=cellular organisms
           RepID=TRPB_HALS3
          Length = 430

 Score =  367 bits (941), Expect = e-100,   Method: Compositional matrix adjust.
 Identities = 197/401 (49%), Positives = 255/401 (63%), Gaps = 27/401 (6%)

Query: 9   FGEFGGMYVPQILMPALRQLEEAFVSAQKDPE--FQAQFNDLLKNYAGRPTALTKCQNIT 66
           FG++GG YVP++LMPA+ +L +A+     D E  F   F   ++++ GRPT LT    ++
Sbjct: 15  FGDYGGQYVPEVLMPAVEELTDAYERYVLDNEDGFVDDFRQRIRSFGGRPTPLTHAPTLS 74

Query: 67  AGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALL 126
                 +YLKREDLLHGGAHK N  LGQ LLAK MGK  I+AETGAGQHG A+A+A A L
Sbjct: 75  QRHGVDVYLKREDLLHGGAHKLNNALGQVLLAKYMGKDRIVAETGAGQHGTATAMACAAL 134

Query: 127 GLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHY 186
            + C IYMG  DV RQ PNVFRMRL  A+V PV  GS TLK+A NE +RDW+ +    HY
Sbjct: 135 EMPCEIYMGRTDVNRQRPNVFRMRLHDADVNPVTVGSGTLKEAINETMRDWATNVADTHY 194

Query: 187 MLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFIN 246
           ++G+  GPHP+P++VR+FQ +I EE +AQ  E+ G LP AVIAC GGGSN +G F  F+ 
Sbjct: 195 VIGSVVGPHPFPSMVRDFQAIISEELRAQSREQLGELPAAVIACAGGGSNTMGAFGAFVG 254

Query: 247 ET--------------NVGLIGVEPGGH--GIETGEHGAP----LKHGRVGIYFGMKAPM 286
                           +V L+ VE GG   G++     AP    L  G  G+  G +  +
Sbjct: 255 SASLPGAPAGTHEPAPDVDLLAVEAGGSRLGVDDDAGYAPNSASLSTGTEGVLHGARTKL 314

Query: 287 MQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGII 346
           +QTE GQI ES+S+SAGLD+  VGP+ A+L  TGR    ++ DD AL AF  L   EG+I
Sbjct: 315 LQTETGQIVESHSVSAGLDYAGVGPELAHLVDTGRITPTNVDDDAALAAFHRLSRDEGVI 374

Query: 347 PALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTV 387
           PALE+SHA+A AL       D +  +VVN+SGRGDKD+ TV
Sbjct: 375 PALETSHAVA-ALDQY----DGDGPVVVNVSGRGDKDLDTV 410


>UniRef50_C1FGK1 Predicted protein n=14 Tax=cellular organisms RepID=C1FGK1_9CHLO
          Length = 444

 Score =  343 bits (880), Expect = 6e-93,   Method: Compositional matrix adjust.
 Identities = 182/390 (46%), Positives = 257/390 (65%), Gaps = 4/390 (1%)

Query: 8   YFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITA 67
           YFGE+GG ++P  L+P + +++  +   ++DP F A+   L K++ GRP+ +  C+ ++ 
Sbjct: 36  YFGEYGGAFLPPPLVPIIDEIKAKYNELKEDPSFWAELRLLEKHFTGRPSPILHCERLSE 95

Query: 68  GTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALL 126
                 +YLKREDL H GAHK N  LG+ALLAK+MGK ++IAETGAGQHGVA A A+AL+
Sbjct: 96  KIGGAQIYLKREDLNHTGAHKINHCLGEALLAKKMGKKKLIAETGAGQHGVALATAAALV 155

Query: 127 GLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHY 186
           GL+C IYMG  D+ ++ PNV RM+++GA VIP   G  TLK+A + A   +     T  Y
Sbjct: 156 GLECDIYMGEVDMAKERPNVVRMKILGANVIPASHGLKTLKEAVDAAFGAYMEDPVTQFY 215

Query: 187 MLGTAAGPHPYPTIVREFQRMIGEETKAQILERE-GRLPDAVIACVGGGSNAIGMFADFI 245
            +G+  GPHP+P +VR+FQ ++G E K Q  E   G+LPD ++ACVGGG NAIG+F  F+
Sbjct: 216 AIGSVVGPHPFPAMVRDFQSVVGREAKEQFKELTGGKLPDNLVACVGGGCNAIGLFTAFL 275

Query: 246 NETNVGLIGVEPGGHGIET-GEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGL 304
            +  V + GVEP G  ++T G+H A L  G  G+  G K  ++Q E G+     + ++GL
Sbjct: 276 GDEKVKMFGVEPSGTDLKTVGKHAATLTLGTPGVIHGFKCVLLQDEGGEPAAVNTCASGL 335

Query: 305 DFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRE 364
           D+P VGPQH YL   GR  Y + TD E ++AF +L   +GIIPALESSHA+A+A+K+ + 
Sbjct: 336 DYPGVGPQHCYLKDIGRVKYETATDVECVDAFMSLARDQGIIPALESSHAVAYAIKLAKT 395

Query: 365 NPDKEQLLVVNLSGRGDKDIFTVHDILKAR 394
            P  E +L VNLSGRGDKD+  V +   A+
Sbjct: 396 LPKTETIL-VNLSGRGDKDVDYVVENFGAK 424


>UniRef50_B0ZSJ6 Tryptophan synthase beta subunit n=3 Tax=rosids RepID=B0ZSJ6_SOYBN
          Length = 461

 Score =  335 bits (859), Expect = 2e-90,   Method: Compositional matrix adjust.
 Identities = 176/388 (45%), Positives = 255/388 (65%), Gaps = 11/388 (2%)

Query: 9   FGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQ----- 63
           FG FGG +VP+ L+ +L QLE  F +A +D  FQA+  + L++YAGR T L   +     
Sbjct: 73  FGRFGGKFVPETLVASLTQLEAEFKNALRDHAFQAELAEALRDYAGRETPLYHAKRLSEY 132

Query: 64  --NITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASAL 121
             ++  G    +YLKREDL H G+HK N  L QA++AKRMG   ++  TG+GQHG+A+A 
Sbjct: 133 YKSVNNGKGPDIYLKREDLNHSGSHKMNNALAQAMIAKRMGCKSVVTATGSGQHGLATAA 192

Query: 122 ASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSY 181
           A A L L C ++M  KD+ RQ  NV  ++L+GA+V  V  G     DA +EA R W G  
Sbjct: 193 ACAKLALDCTVFMADKDIHRQYSNVRLIKLLGAQVEAVDGG---FTDAASEAFRYWVGDL 249

Query: 182 ETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMF 241
           E  +++ G+A GPHP PT+VREFQ +IG+ET+ Q LE+ G  PD ++A VG GSNA+G+F
Sbjct: 250 ENRYHLSGSAVGPHPCPTMVREFQSVIGKETRMQALEKWGGKPDVLVASVGTGSNALGLF 309

Query: 242 ADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSIS 301
            +FI + +V  +GVE GG G+E+G+H + L  G VG Y G  + ++Q +DGQI   +SI+
Sbjct: 310 HEFIADKDVRFVGVEAGGLGLESGKHSSTLTTGEVGAYHGAISYLLQDQDGQIIHPHSIA 369

Query: 302 AGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKM 361
           AG+++P VGP+ ++L  +GRA++    D+EAL+A++ LC  EGI P+LE++HALA   K+
Sbjct: 370 AGMEYPGVGPELSFLKESGRAEFCVANDEEALDAYQRLCKLEGIFPSLEAAHALAILDKL 429

Query: 362 MRENPDKEQLLVVNLSGRGDKDIFTVHD 389
           +    +  + +VVN SGRGDKD   V +
Sbjct: 430 VPTLCNGTK-VVVNCSGRGDKDAAIVFN 456


>UniRef50_C0QZH7 Tryptophan synthase beta subunit n=4 Tax=Bacteria
           RepID=C0QZH7_BRAHW
          Length = 417

 Score =  327 bits (839), Expect = 4e-88,   Method: Compositional matrix adjust.
 Identities = 175/364 (48%), Positives = 230/364 (63%), Gaps = 5/364 (1%)

Query: 32  FVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTN-TTLYLKREDLLHGGAHKTNQ 90
           F+    D EF ++  +L  ++ GRPT L   +N++       +Y+K E L H GAHK N 
Sbjct: 32  FLHYINDKEFLSELEELRADFIGRPTPLMYAKNLSEKIGGAKIYVKLEGLAHTGAHKINN 91

Query: 91  VLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMR 150
            +GQALLAK+MGK +IIAETGAGQHG+A+A A A LGL+C IYMG  DV+RQ PNV  M 
Sbjct: 92  SIGQALLAKKMGKKKIIAETGAGQHGLATAAACAKLGLECSIYMGEIDVKRQQPNVASME 151

Query: 151 LMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGE 210
           L GA V+ V  G   LKDA + AL DW    +  HY+LG+A GP PYP IVR FQ +IG 
Sbjct: 152 LYGANVVSVTKGGRGLKDAVDMALEDWVKDLKDTHYLLGSAVGPSPYPDIVRTFQSVIGR 211

Query: 211 ETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAP 270
           E   QI E+   +  A+IACVGGGSNAIG F  FI   N  LI VE GG  +  GE+   
Sbjct: 212 ELDKQIQEKNLNV-KALIACVGGGSNAIGFFEPFIERENPKLIAVEAGGISMNLGENAIR 270

Query: 271 LK--HGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSIT 328
           ++  + +     G  +  +  E+G+I E+ SISAGLD+P VGPQ AYL  +GR ++   T
Sbjct: 271 MQNPYAKDVAAQGYMSKFILKENGEISETMSISAGLDYPGVGPQLAYLGESGRIEFTYAT 330

Query: 329 DDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVH 388
           D EA+ A K    HEG+I ALES+HA A A++  ++   K+ +++VN+SGRGDKDIF   
Sbjct: 331 DKEAINAVKEFASHEGVIFALESAHAGAKAIEYAKQY-SKDDVIIVNMSGRGDKDIFITS 389

Query: 389 DILK 392
            I +
Sbjct: 390 PIFR 393


>UniRef50_B7G4U3 Tryptophan synthase, beta chain n=3 Tax=cellular organisms
           RepID=B7G4U3_PHATR
          Length = 385

 Score =  307 bits (787), Expect = 4e-82,   Method: Compositional matrix adjust.
 Identities = 167/378 (44%), Positives = 230/378 (60%), Gaps = 23/378 (6%)

Query: 8   YFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITA 67
           YFGE+GG  +P  L+  + ++ E++    +   FQ + + L K++ GRP+ +   + +T 
Sbjct: 19  YFGEYGGQQLPPQLVEIMNEISESYEKLIRTDAFQIELDSLNKDFIGRPSPIFYARRLTE 78

Query: 68  GTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALL 126
                 ++LKREDL H GAHK N  LG+ALLAK MGKT+++AETGAGQHGVA A A AL+
Sbjct: 79  KIGGARIFLKREDLNHTGAHKINHCLGEALLAKHMGKTKVLAETGAGQHGVALATACALI 138

Query: 127 GLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHY 186
           G++C I+MG  DVE+++PNV +MR++G ++I V  G+ TLKDA +    ++        Y
Sbjct: 139 GIECEIHMGQVDVEKEAPNVTKMRILGCKLITVTRGTRTLKDAVDSVFEEYLKDPVNYFY 198

Query: 187 MLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFIN 246
            +G+                      KA      G LPDA++AC GGG NA G+F  F+ 
Sbjct: 199 AIGSVI-------------------FKASWDLEGGALPDAIVACGGGGCNARGIFTAFLE 239

Query: 247 ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDF 306
           +  V LIGVEP G G+ET +H A +  G  G   GM    +Q E G+    YSI++GLD+
Sbjct: 240 DPEVQLIGVEPAGRGLETSDHAATMTLGVKGSIHGMNCYNLQDETGEPLPVYSIASGLDY 299

Query: 307 PSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRE-N 365
           P VGPQH  L   GR  YV++TD E L+AF  L   EGIIPALES+HA+A+A K+  E  
Sbjct: 300 PGVGPQHCLLKDIGRTKYVAVTDQECLDAFMQLSRVEGIIPALESAHAVAYATKLAVEIG 359

Query: 366 PDKEQLLVVNLSGRGDKD 383
           P K   ++VNLSGRGDKD
Sbjct: 360 PGKT--ILVNLSGRGDKD 375


>UniRef50_B8MZR1 Trytophan synthase alpha subunit, putative n=2 Tax=Leotiomyceta
           RepID=B8MZR1_ASPFN
          Length = 641

 Score =  296 bits (757), Expect = 1e-78,   Method: Compositional matrix adjust.
 Identities = 168/391 (42%), Positives = 226/391 (57%), Gaps = 61/391 (15%)

Query: 9   FGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNIT-- 66
           FG FGG Y P+ L   L +LE  F +A  DP F  ++      Y GRP++L +   +T  
Sbjct: 299 FGIFGGQYAPEALTTCLAELEAGFQAALDDPTFWEEYRSYYP-YMGRPSSLHQATRLTEH 357

Query: 67  -AGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASAL 125
             G N  ++LKREDL H G+HK N  LGQ L+A                           
Sbjct: 358 VGGAN--IWLKREDLNHTGSHKINNALGQILIA--------------------------- 388

Query: 126 LGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAH 185
                                   R +GA VIPV SGS TL+DA NEA R W    +T H
Sbjct: 389 ------------------------RRLGATVIPVESGSRTLRDAVNEAFRAWIVRLDTTH 424

Query: 186 YMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFI 245
           Y++G+A GPHP+PT+VR FQ +IG ETKAQ+ E  G+ PDAV+ACVGGGSN++GMF  F 
Sbjct: 425 YIIGSAIGPHPFPTMVRTFQSVIGNETKAQMQEL-GKSPDAVVACVGGGSNSVGMFYPFS 483

Query: 246 NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLD 305
            + +V L+GVE  G G++T  H A L  G VG+  G++  ++Q E GQI +++SISAGLD
Sbjct: 484 KDLSVQLVGVEAAGDGLDTDRHSATLTGGSVGVLHGVRTYILQDEHGQISDTHSISAGLD 543

Query: 306 FPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRE- 364
           +P VGP+ A+   + RA ++S TD +A E F+ L   EGIIPALE+SHA+  A++  ++ 
Sbjct: 544 YPGVGPELAHWKESKRATFLSATDAQAFEGFRLLSQLEGIIPALETSHAVWGAIQTAKKL 603

Query: 365 NPDKEQLLVVNLSGRGDKDIFTVHDILKARG 395
            P K+  LV+ LSGRGDKD+ +V D L   G
Sbjct: 604 GPGKD--LVLCLSGRGDKDVQSVADGLPTIG 632


>UniRef50_D1NGU1 DNA (Cytosine-5-)-methyltransferase (Fragment) n=3 Tax=Haemophilus
           influenzae HK1212 RepID=D1NGU1_HAEIN
          Length = 256

 Score =  295 bits (755), Expect = 2e-78,   Method: Compositional matrix adjust.
 Identities = 136/168 (80%), Positives = 148/168 (88%)

Query: 38  DPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALL 97
           DP FQA+F DLLKNYAGRPTALT C N+T GT   +YLKREDLLHGGAHKTNQVLGQ LL
Sbjct: 1   DPTFQAEFADLLKNYAGRPTALTLCHNLTKGTKAKIYLKREDLLHGGAHKTNQVLGQILL 60

Query: 98  AKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVI 157
           AKRMGKT IIAETGAGQHGVA+ALA A+L + CRIYMGAKDV+RQSPNVFRMRLMGAEVI
Sbjct: 61  AKRMGKTRIIAETGAGQHGVATALACAMLDMPCRIYMGAKDVDRQSPNVFRMRLMGAEVI 120

Query: 158 PVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQ 205
           PV  GS +LKDAC EA+RDWS +YET HY+LGTAAGPHP+PTIVREF 
Sbjct: 121 PVQKGSCSLKDACCEAMRDWSANYETTHYLLGTAAGPHPFPTIVREFN 168


>UniRef50_Q1V1Q0 Tryptophan synthase beta chain 1 n=6 Tax=root RepID=Q1V1Q0_PELUB
          Length = 410

 Score =  278 bits (710), Expect = 3e-73,   Method: Compositional matrix adjust.
 Identities = 157/391 (40%), Positives = 227/391 (58%), Gaps = 12/391 (3%)

Query: 10  GEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAG- 68
           G+FGG ++P+ L   +  L E F   + D +F  + +   KNY G PT+  K QN++   
Sbjct: 21  GKFGGNFIPETLKKPIEDLTELFEKLRYDKKFLKERDYYFKNYIGSPTSFIKLQNLSDHL 80

Query: 69  TNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGL 128
           +   +Y K     +GGAHK        L+AK+ GK  ++ +TGAG  G   ++A+   GL
Sbjct: 81  SGAQIYAKMVSEANGGAHKIYNATVHCLIAKKAGKKYVVGDTGAGYAGKMLSMAAKKFGL 140

Query: 129 KCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYML 188
           KC+I+MGAKD++RQ PNV  M+  GAEV+PV+SGS TL DA +E +R W  + +  H  +
Sbjct: 141 KCKIFMGAKDIKRQKPNVDAMKKNGAEVVPVYSGSQTLVDAVSECMRYWVSNCDNTHMCV 200

Query: 189 GTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAV--IACVGGGSNAIGMFADFI- 245
           G+  GP+ +  I       I  E K QI     ++P  +  I CVGGGS+A G +++FI 
Sbjct: 201 GSTVGPNIFVKICGWSTAQISRELKVQIQSEFKKMPKKIKLINCVGGGSSAYGFWSEFID 260

Query: 246 -NETNVGLIGVEPGGHGIETGEHGAPLKHG-RVGIYFGMKAPMMQTEDGQIEESYSISAG 303
            ++  + LIGVE GG    +  H APL +G ++GI  G  A + Q  +GQI ++ SISAG
Sbjct: 261 YDKKQIELIGVEAGGPK-NSKLHAAPLTNGAKLGILHGAAAYVCQNSEGQINDTASISAG 319

Query: 304 LDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMR 363
           LD+P V P H +L  T RA Y S TD+ AL A+K +   E I P+LE SHA A A+K+  
Sbjct: 320 LDYPGVSPIHCFLKDTKRARYTSATDEAALNAYKLVTKLEKINPSLEPSHAFAEAIKIAP 379

Query: 364 ENPDKEQLLVVNLSGRGDKDIFTVHDILKAR 394
           +  +K+ +++VN  G   KD     DILK R
Sbjct: 380 K-LNKDTIIIVNSCGDAKKD----RDILKER 405


>UniRef50_B6HPP8 Pc22g00910 protein n=1 Tax=Penicillium chrysogenum Wisconsin
           54-1255 RepID=B6HPP8_PENCW
          Length = 518

 Score =  264 bits (674), Expect = 5e-69,   Method: Compositional matrix adjust.
 Identities = 145/380 (38%), Positives = 226/380 (59%), Gaps = 19/380 (5%)

Query: 9   FGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITA- 67
           +G +GG + P+ +M  L +L   F +   DP F  ++    ++   R T L     +T+ 
Sbjct: 147 YGSYGGRFAPESIMGFLYELTSFFEATVSDPSFWEEYATFQRD---RVTPLHMAGKLTSL 203

Query: 68  GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLG 127
               T++LKRED    G+HKT  + GQ LLA+RMG++EI+ +  + +HG  +A   A LG
Sbjct: 204 AGGATIWLKREDKNEYGSHKTRNITGQLLLARRMGRSEIVTDCASAKHGKVTAAMCARLG 263

Query: 128 LKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVH--SGSATLKDACNEALRDWSGSYETAH 185
           L+C + +GA D   Q  +V  M+ +GA+V+     SG   L+ A  EALR    ++E+A+
Sbjct: 264 LRCVVVIGADDASAQEKDVLEMKSLGAKVLTARAPSGMGGLRAAITEALRYAVCNHESAY 323

Query: 186 YMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFI 245
           Y++G+  GP P PT+ R FQ ++GEE  AQ+ E  GR PDA++  VG GS AIG+F  F+
Sbjct: 324 YLMGSPVGPSPLPTLARTFQSLLGEEVAAQMHEAAGRQPDALVTAVGSGSGAIGLFRPFL 383

Query: 246 NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLD 305
           +++++ L+GVE          + A L  G +G+  G +  ++Q  DGQI +S+SIS  ++
Sbjct: 384 HDSSIRLVGVE--------AANAAALTDGGLGVLQGARTLLLQNHDGQILDSHSISPDMN 435

Query: 306 FPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRE- 364
             +VGP+ A+   +GR +  + TD  AL+ F+TL  HEGI+P L+SSHA++ AL + RE 
Sbjct: 436 LSTVGPEVAHWKDSGRIEISTATDAVALDGFRTLQQHEGILPGLDSSHAVSKALDLAREL 495

Query: 365 NPDKEQLLVV----NLSGRG 380
            P K  +L+V    N+S RG
Sbjct: 496 GPGKNVVLMVTGCDNISVRG 515


>UniRef50_A1DP73 Tryptophan synthase n=4 Tax=Trichocomaceae RepID=A1DP73_NEOFI
          Length = 460

 Score =  256 bits (653), Expect = 1e-66,   Method: Compositional matrix adjust.
 Identities = 149/375 (39%), Positives = 211/375 (56%), Gaps = 22/375 (5%)

Query: 9   FGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNIT-- 66
           FG FGG + P+  M AL++L   F     D  F  +F   L +   RP+ L   +N+T  
Sbjct: 97  FGTFGGCFAPESQMDALQELTLTFDRLISDYGFWKEF---LSSPGIRPSPLRFAENLTRI 153

Query: 67  -AGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASAL 125
             G N  ++LKREDL   G+H    ++GQALLA+R+GK E++ E G+ +HG+  A     
Sbjct: 154 AGGAN--IWLKREDLNQHGSHNIRSIVGQALLARRLGKAEVVMECGSARHGIVCAATCTR 211

Query: 126 LGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIP----VHSGSATLKDACNEALRDWSGSY 181
           L +KC I MG++D   Q  +V  +R +GA V+       SG  TL+ A NEALR      
Sbjct: 212 LNMKCTILMGSRDATDQKDSVDMIRKLGATVLTADMGASSGRGTLRAAVNEALRYSVAHL 271

Query: 182 ETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREG-RLPDAVIACVGGGSNAIGM 240
            T ++++    GPHP PTI R FQ ++GEE K Q     G RLPDA+++ VG GS A+GM
Sbjct: 272 STTYHIMSGPIGPHPLPTITRTFQSILGEEIKTQFGGTSGDRLPDALVSPVGPGSAAVGM 331

Query: 241 FADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSI 300
           F  FI   +V L+G+E            APL HG +G+  G +  ++Q E GQI +S SI
Sbjct: 332 FYPFIEHPSVKLLGIE--------AADAAPLSHGDIGVLHGCRTYLLQDEHGQILDSGSI 383

Query: 301 SAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALK 360
           S  LDFPSVGP+ A+   T R +YV+ TD EAL     L   EGI+    + +A+   ++
Sbjct: 384 SPDLDFPSVGPELAHWKETARVEYVTATDAEALRGVDILRSQEGIVSGAMTGYAVERTIR 443

Query: 361 MMRE-NPDKEQLLVV 374
           + RE  P K+ +L+V
Sbjct: 444 LARELGPGKDVVLLV 458


>UniRef50_C8VGH6 Putative uncharacterized protein n=2 Tax=Emericella nidulans
           RepID=C8VGH6_EMENI
          Length = 443

 Score =  224 bits (570), Expect = 5e-57,   Method: Compositional matrix adjust.
 Identities = 133/369 (36%), Positives = 196/369 (53%), Gaps = 26/369 (7%)

Query: 9   FGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAG 68
            G FGG + P++ M  L  L   F S   D  F  +F+    +   RP+ L    ++T  
Sbjct: 75  LGRFGGQFAPELQMDLLLDLPSVFHSVLSDNRFWTEFS---ASPFLRPSPLHLAHSLTKA 131

Query: 69  TN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLG 127
                ++LKR+DL   G+++T  ++GQ L A+ +GKTEI  E G   HG+  A   A + 
Sbjct: 132 VGGANIWLKRDDLNPFGSYQTRNIVGQILFAQHIGKTEISMECGFAGHGLFCATMCARMN 191

Query: 128 LKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS-----GSATLKDACNEALRDWSGSYE 182
           +KC I MGA D+  Q   V  M+ +GA V+ V       GS TL+ A NEALR       
Sbjct: 192 MKCTILMGASDIAAQPDAVEEMKQLGATVVSVQCSISDDGSGTLRAATNEALRYSLTRLN 251

Query: 183 TAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGR-------LPDAVIACVGGGS 235
           + +++     GPHP PTI R FQ ++G+E K    E  GR        P A+++    G+
Sbjct: 252 STYHISTGTVGPHPLPTITRTFQSLLGQEIKICSSELPGRGRRKNNFRPSALVST--SGA 309

Query: 236 NAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIE 295
            A+GMFA FI++  V LI VE            APL HG  G+ +G K  ++Q E+GQI 
Sbjct: 310 AALGMFAPFISDPAVRLIAVE--------AADAAPLTHGSPGVMYGCKTLLLQDENGQIL 361

Query: 296 ESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHAL 355
            S+SIS  L+FP  GP+ A+    GR + V+ + +EA+   + LC  EGI+P L +SHA+
Sbjct: 362 PSHSISPDLNFPCAGPELAHWRDLGRLETVTASSEEAVRGLRILCESEGIVPGLATSHAV 421

Query: 356 AHALKMMRE 364
              +++ R+
Sbjct: 422 LETVRVARQ 430


>UniRef50_Q56YC7 Tryptophan synthase beta chain 1 n=3 Tax=cellular organisms
           RepID=Q56YC7_ARATH
          Length = 141

 Score =  144 bits (362), Expect = 8e-33,   Method: Compositional matrix adjust.
 Identities = 73/136 (53%), Positives = 98/136 (72%), Gaps = 1/136 (0%)

Query: 252 LIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGP 311
           +IGVE  G G+++G+H A L  G VG+  G  + ++Q +DGQI E +SISAGLD+P VGP
Sbjct: 1   MIGVEAAGFGLDSGKHAATLTKGDVGVLHGAMSYLLQDDDGQIIEPHSISAGLDYPGVGP 60

Query: 312 QHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQL 371
           +H++    GRA+Y SITD+EALEAFK +   EGIIPALE+SHALA+  K+     D  + 
Sbjct: 61  EHSFFKDMGRAEYYSITDEEALEAFKRVSRLEGIIPALETSHALAYLEKLCPTLSDGTR- 119

Query: 372 LVVNLSGRGDKDIFTV 387
           +V+N SGRGDKD+ TV
Sbjct: 120 VVLNFSGRGDKDVQTV 135


>UniRef50_Q9Y8T5 Tryptophan synthase beta chain 1 n=10 Tax=Thermoprotei
           RepID=TRPB1_AERPE
          Length = 427

 Score =  134 bits (337), Expect = 6e-30,   Method: Compositional matrix adjust.
 Identities = 122/372 (32%), Positives = 172/372 (46%), Gaps = 48/372 (12%)

Query: 54  GRPTALTKCQNIT----AGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAE 109
           GRPT L + + +           +Y K E +L  G+HK N  + QA  AK  G  EI+ E
Sbjct: 70  GRPTPLIRAEGLEKVLGVKGRVRIYYKSEAVLPTGSHKINTAIAQAYYAKLDGAKEIVTE 129

Query: 110 TGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDA 169
           TGAGQ G+A++ A+AL+GLK  ++M A   + +      M   GA VI   S  + L D 
Sbjct: 130 TGAGQWGLAASTAAALMGLKATVFMTASSFKSKIQRRLLMEAQGARVI---SSPSKLTDT 186

Query: 170 CNEALRDWSGSY---------ETAHYMLGTAAGPHPY-PTIVRE----FQRMIGEETKAQ 215
             EAL ++  ++         E   Y L   +G   Y P  V E     Q +IG E   Q
Sbjct: 187 GREALEEYGSTHPGSLGLAIAEAVEYTL--ESGDRRYLPGSVLEAVLMHQTVIGLEALDQ 244

Query: 216 ILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIE-----TGEHGAP 270
           + E     PD V+ACVGGGSN    F  F       +IG    G G E       E  A 
Sbjct: 245 LPEE----PDVVVACVGGGSN----FGGF----TYPMIGARLRGEGFEKTRFIAAESTAA 292

Query: 271 LKHGR-----VGIYFGMKAPM--MQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRAD 323
            K  R      G+   +  P+  M T   +     S +AGL +  V P  + L   G  +
Sbjct: 293 PKLTRGEYRYDGLDSSLILPLAKMYTLGHRYTPPPSHAAGLRYHGVSPSLSILRRLGLVE 352

Query: 324 YVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKD 383
             +I  +EAL +   +   EG++PA ESSHA+A A ++ R+ PD   ++  NLSG G  D
Sbjct: 353 AEAIPQEEALASILLMARSEGVVPAPESSHAVALAARIARKLPDG-SVVAFNLSGHGLLD 411

Query: 384 IFTVHDILKARG 395
           +  +   L+ RG
Sbjct: 412 LDALQKALEIRG 423


>UniRef50_B6YSU5 Tryptophan synthase beta chain n=232 Tax=cellular organisms
           RepID=TRPB_THEON
          Length = 443

 Score =  134 bits (336), Expect = 8e-30,   Method: Compositional matrix adjust.
 Identities = 118/382 (30%), Positives = 166/382 (43%), Gaps = 66/382 (17%)

Query: 54  GRPTALTKCQNITAGTNTT--LYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETG 111
           GRPT L +  N+     T   +Y K E     G+HK N  L QA  AK+ G   ++ ETG
Sbjct: 75  GRPTPLFRATNLEKALETPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETG 134

Query: 112 AGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSA------- 164
           AGQ G A +LA AL+G+  R+YM      ++      MRL GAE+ P  S          
Sbjct: 135 AGQWGTALSLAGALMGINVRVYMARASFYQKPYRKTIMRLYGAEIYPSPSDRTEIGRKFL 194

Query: 165 ------------TLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEET 212
                        + +A  + LRD     E A Y LG+          V   Q +IG E 
Sbjct: 195 SEDPNHPGGLGIAISEAIEDVLRD-----EKARYALGSVL------NHVLMHQTVIGLEA 243

Query: 213 KAQILEREGRLPDAVIACVGGGSNAIGMFADFINE-----TNVGLIGVEPGG-----HGI 262
           K Q+ E E   PD +I CVGGGSN  G+   F+ +      +   I VEP        G+
Sbjct: 244 KEQMKEFED--PDVIIGCVGGGSNFAGLAYPFVKDRLDGKADYEFIAVEPRAAPSMTRGV 301

Query: 263 ETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSI----SAGLDFPSVGPQHAYLNS 318
            T ++G            G   P M+     +  +Y +    + GL +  + P  + L +
Sbjct: 302 YTYDYGDS----------GGLTPKMKMH--TLGHTYYVPPIHAGGLRYHGLAPTLSILIN 349

Query: 319 TGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALA----HALKMMRENPDKEQLLVV 374
            G    V+    E  EA +     EGI+PA ES+HA+      ALK   E   KE++++ 
Sbjct: 350 HGIVRPVAYHQTEVFEAARLFAKTEGIVPAPESAHAVKAAIDRALKAKEEG--KEEVILF 407

Query: 375 NLSGRGDKDIFTVHDILKARGE 396
           NLSG G  D+    D L  + E
Sbjct: 408 NLSGHGLLDLKGYEDFLDGKLE 429


>UniRef50_C7N0P7 Pyridoxal-phosphate dependent TrpB-like enzyme n=8 Tax=Bacteria
           RepID=C7N0P7_SLAHD
          Length = 470

 Score =  113 bits (282), Expect = 1e-23,   Method: Compositional matrix adjust.
 Identities = 112/358 (31%), Positives = 156/358 (43%), Gaps = 40/358 (11%)

Query: 55  RPTALTKCQNITA--GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGA 112
           RP+ L +  N+    GT   +Y K E     G+HK N  L QA  A   G T I  ETGA
Sbjct: 82  RPSPLCRAYNLEKALGTPAKIYYKFEGNNTSGSHKLNSALAQAYYAHEQGLTTITTETGA 141

Query: 113 GQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATL--KDAC 170
           GQ G A + A+A  GL C ++M     E++      M+  GA+V P  S    +  K   
Sbjct: 142 GQWGTALSEAAAHYGLNCDVFMVRASYEQKPFRRSVMQTFGAQVTPSPSQETEIGRKMYA 201

Query: 171 NEALRDWSGSYETA----------------HYMLGTAAGPHPYPTIVREFQRMIGEETKA 214
           +EA R  SGS  TA                 Y LG+          V   Q +IG E+ A
Sbjct: 202 DEANR--SGSLGTAISEAVERALHVPENKGRYQLGSVL------NQVVLHQSIIGLESLA 253

Query: 215 QILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAP-LKH 273
              E  G  PD VI C GGGSN  G+ A F+ +    L G +P    I       P L  
Sbjct: 254 AFDEL-GEYPDVVIGCAGGGSNLGGLIAPFMRDK---LTGEKPDTRFIAVEPASCPSLTR 309

Query: 274 GRVGIYF---GMKAPM--MQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSIT 328
           GR    F   G   P+  M T       S   + GL +  + P  + L   G  D VS+ 
Sbjct: 310 GRYAYDFADTGQTCPLVKMYTLGNGFIPSPDHAGGLRYHGMSPIISKLKHDGYLDAVSVK 369

Query: 329 DDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPD--KEQLLVVNLSGRGDKDI 384
             +   A +     E I+PA ES+HA+  A++  R+  +  +E++++  L+G G  D+
Sbjct: 370 QTDVFAAAEEFAKLETILPAPESAHAICVAMEEARKCAETGEEKVILFGLTGTGYFDM 427


>UniRef50_Q9WZ09 Tryptophan synthase beta chain 2 n=6 Tax=Bacteria RepID=TRPB2_THEMA
          Length = 422

 Score =  107 bits (267), Expect = 8e-22,   Method: Compositional matrix adjust.
 Identities = 110/366 (30%), Positives = 158/366 (43%), Gaps = 45/366 (12%)

Query: 48  LLKNYA-GRPTALTKCQNITAGTNTT--LYLKREDLLHGGAHKTNQVLGQALLAKRMGKT 104
           +LK YA  RPT L +   +     T   +Y K E +   G+HK N  + QA   K  G  
Sbjct: 69  VLKEYAVYRPTPLIRATFLEEYLQTPARIYYKYEGVSPTGSHKPNTAIAQAYYNKIEGVK 128

Query: 105 EIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS--- 161
            ++ ETGAGQ G A + A A  GL+ +++M     +++    + M L G +V P  S   
Sbjct: 129 RLVTETGAGQWGSALSYAGAKFGLEVKVFMVKVSYQQKPMRKYMMNLFGGKVTPSPSEET 188

Query: 162 ------------GSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIG 209
                          +L  A +EAL + + S     Y LG+    H     V   Q +IG
Sbjct: 189 NFGRKILSEDPDNPGSLGIAISEAL-EVAVSDPNTKYSLGSVLN-H-----VLLHQTVIG 241

Query: 210 EETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINET----NVGLIGVEPGGHGIETG 265
            E K Q LE  G  PD ++ C GGGSN  G    F+ +     ++  +  EP        
Sbjct: 242 LEIKKQ-LELIGEKPDILLGCHGGGSNFGGTILPFVPDKLSGRDIRFVACEPAA------ 294

Query: 266 EHGAPLKHGRVGIYFGMKA---PM--MQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTG 320
                L  G     FG  A   P+  M T           + GL +    P  A L   G
Sbjct: 295 --CPSLTKGNYDYDFGDTAGLTPLLKMYTLGKDFIPPKIHAGGLRYHGSAPIIARLVKEG 352

Query: 321 RADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPD--KEQLLVVNLSG 378
             +  +   DE  EA K     EGIIPA ES+HA+A A++  ++  +  KE+++V  LSG
Sbjct: 353 LVEAQAFDQDETFEAAKIFAKLEGIIPAPESAHAIAGAIREAKKAKEEGKERVIVFTLSG 412

Query: 379 RGDKDI 384
            G  D+
Sbjct: 413 HGLLDL 418


>UniRef50_A8F8F7 Tryptophan synthase beta chain n=12 Tax=cellular organisms
           RepID=TRPB_THELT
          Length = 422

 Score =  106 bits (265), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 109/366 (29%), Positives = 155/366 (42%), Gaps = 45/366 (12%)

Query: 48  LLKNYA-GRPTALTKCQNITAGTNTT--LYLKREDLLHGGAHKTNQVLGQALLAKRMGKT 104
           +L+ YA  RPT L +   +     T   +Y K E     G+HKTN  L QA   K  G  
Sbjct: 69  VLEEYAVFRPTPLFRATYLEEFLQTPARIYYKYEGASPTGSHKTNTALAQAYYNKISGTE 128

Query: 105 EIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS--- 161
            ++ ETGAGQ G A   + A  GLK  ++M     E++    + MRL   +V+P  S   
Sbjct: 129 RLVTETGAGQWGSALCYSGAKFGLKVNVFMVKISYEQKPMRKYLMRLFDGDVVPSPSEKT 188

Query: 162 ------------GSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIG 209
                          +L  A +EA+ + + S     Y LG+    H     V   Q +IG
Sbjct: 189 SFGKSILASNSENPGSLGIAISEAI-EITLSDSRTKYSLGSVLN-H-----VLLHQTVIG 241

Query: 210 EETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINE----TNVGLIGVEPGGHGIETG 265
            E K Q LE  G  PD ++ C GGGSN  G    FI +      +  +  EP        
Sbjct: 242 LELKKQ-LEVLGEKPDVILGCHGGGSNFGGTVLPFIPDKLSGKEIKFVACEPTA------ 294

Query: 266 EHGAPLKHGRVGIYFGMKAPM-----MQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTG 320
                L  GR    +G  A M     M T           + GL +    P  + L   G
Sbjct: 295 --CPSLTRGRYDYDYGDTAGMTPLLKMYTLGKDFIPPKIHAGGLRYHGAAPIISRLVKEG 352

Query: 321 RADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKE--QLLVVNLSG 378
             + V+   DE   A K     EGI+PA ESS+A+A A++  ++  +    +++V NLSG
Sbjct: 353 LIEAVAFDQDEIFSAAKLFAKLEGIVPAPESSYAIAGAIREAKKAKEHNIPRVVVFNLSG 412

Query: 379 RGDKDI 384
            G  D+
Sbjct: 413 HGLFDL 418


>UniRef50_B1KQQ7 Pyridoxal-5'-phosphate-dependent protein beta subunit n=2
           Tax=Proteobacteria RepID=B1KQQ7_SHEWM
          Length = 440

 Score =  103 bits (258), Expect = 9e-21,   Method: Compositional matrix adjust.
 Identities = 105/363 (28%), Positives = 164/363 (45%), Gaps = 35/363 (9%)

Query: 53  AGRPTALTKCQNITAGTNTT--LYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAET 110
            GRPT L +  ++     T   +Y KRED +  G+ K +  + QA  AK+ G+  +I+ET
Sbjct: 87  CGRPTPLRRALSLEKHLKTPARIYFKREDTMATGSFKLSTAVAQAYYAKQEGREILISET 146

Query: 111 GAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDAC 170
           GAGQ G++ AL S + GL  RI+M    +E++      M+++G EV P    S + K  C
Sbjct: 147 GAGQWGMSVALVSQMFGLDARIFMARCSLEQKPYRQHYMKMLGCEVYP----SPSTKTEC 202

Query: 171 NEAL------------RDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILE 218
            + L               S + E A    G+A         V   Q ++G E K Q+  
Sbjct: 203 GKELLLQTPGHPGSIGSAISEAIENALDTPGSAYLSGSNVNHVHLHQTLLGLEVKQQLSM 262

Query: 219 REGRLPDAVIACVGGGSNAIGMFADFINETNVG----LIGVEPGGHGIETGEHGAPLKHG 274
                 D ++ACV GGSN  G    F+ E N G    ++GVE       T       ++ 
Sbjct: 263 AGESNVDHLVACVSGGSNLCGFMMPFLPEKNSGAKIDMLGVESTASPRLT---QGTYEYC 319

Query: 275 RVGIYFGMKAPMMQTEDGQIEESYSIS----AGLDFPSVGPQHAYLNSTGRADYVSITDD 330
           R  +  G    ++    G   ESY  +     GL   +  P  + L   G     ++ + 
Sbjct: 320 RSDVA-GYTPEVLSHSMG---ESYIPAPVHVGGLRNHNSSPLVSLLCREGILRAEALDEF 375

Query: 331 EALEAFKTLCLHEGIIPALESSHALAHALKMMREN--PDKEQLLVVNLSGRGDKDIFTVH 388
            A +A + +   EGI+ A ESSHA+A A+ +  +    +KE ++V   SG G  D+   +
Sbjct: 376 NAFKAGQIMLKTEGILVAPESSHAVAAAIDLAEKARIENKESVIVFLASGNGFLDLQGYN 435

Query: 389 DIL 391
           D+L
Sbjct: 436 DVL 438


>UniRef50_C7DG26 Pyridoxal-phosphate dependent TrpB-like enzyme n=1 Tax=Candidatus
           Micrarchaeum acidiphilum ARMAN-2 RepID=C7DG26_9EURY
          Length = 446

 Score = 99.8 bits (247), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 100/362 (27%), Positives = 152/362 (41%), Gaps = 53/362 (14%)

Query: 55  RPTALTKCQNITA--GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGA 112
           RPT + + + + A  G    +Y+K E   + G+HK N  + QA  AK  G   +  ETGA
Sbjct: 87  RPTPIIRARQLEAHFGNKVKIYMKMEGFTYVGSHKINSSIPQAYYAKADGAKFVTTETGA 146

Query: 113 GQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNE 172
           GQ G A ALA++L GL+ +I+M       +    + M + G EV P  S           
Sbjct: 147 GQWGSAVALAASLFGLESKIFMVKVSYAGKPYRRYLMNMFGGEVHPSPSELTGFGRGILR 206

Query: 173 ALRDWSGS----------YETAH---YMLGTAAGPHPYPTIVREFQRMIGEETKAQILER 219
              D  GS          Y   H   Y++G+             F+ + G E K Q +E 
Sbjct: 207 KEPDSPGSLGMAITDAVEYAKEHGGKYVVGSVVNSD------LMFKSIAGLEAKKQ-MES 259

Query: 220 EGRLPDAVIACVGGGSNAIGMFADFINET-NVGLIG---VEPGGHGI------------- 262
            G  PD VI CVGGGSN  G+   F+ E    G I    +  G   I             
Sbjct: 260 IGEDPDYVIGCVGGGSNYAGLAYPFLEEELKAGKIRRRYIAAGSAEIPKMTKGKYEYDYP 319

Query: 263 ETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRA 322
           +TG+    LK   VG  F +  P+              + GL + +V P  + L S G  
Sbjct: 320 DTGKVLPQLKMYTVGHDF-VPPPIY-------------AGGLRYHAVAPSLSLLMSKGIV 365

Query: 323 DYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDK 382
           +      +E+    K     EG +PA E+SH+     ++ ++   K+ +++++ SG G  
Sbjct: 366 EARDYDQNESFRYAKLYSKIEGYVPAPETSHSFPIIEEIAKKAGSKKPVVLMSFSGNGML 425

Query: 383 DI 384
           D+
Sbjct: 426 DL 427


>UniRef50_D2L2T8 Pyridoxal-phosphate dependent TrpB-like enzyme n=2 Tax=Bacteria
           RepID=D2L2T8_9DELT
          Length = 447

 Score = 95.9 bits (237), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 108/414 (26%), Positives = 166/414 (40%), Gaps = 58/414 (14%)

Query: 18  PQILMP-ALRQLEEAFVSAQKDPEFQAQ--------FNDLLKNYAGRPTALTKCQNI--T 66
           PQ   P +  QLE  F  A  + E   +          D+ + Y  RPT L + + +   
Sbjct: 33  PQTKQPVSPEQLEAIFPKAVIEQELSTERWLPIPEPVRDIYRLY--RPTPLVRAKRLEEA 90

Query: 67  AGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALL 126
            G    ++ K E +   G+HK N  + QA   K  G   I  ETGAGQ G A + A ++ 
Sbjct: 91  LGVKCKIFYKNESVSPAGSHKPNTAIPQAYYNKLEGVRRISTETGAGQWGTALSFACSMF 150

Query: 127 GLKCRIYMGAKDVERQSPNVFRMRLMGAEVI-----------------PVHSGSATLKDA 169
           G+ C +YM      ++      +   G E+                  P  SGS  L  A
Sbjct: 151 GMACTVYMVKVSYNQKPYRRILINAYGGEIFASPSENTKTGRAVLASDPDCSGSLGL--A 208

Query: 170 CNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIA 229
            +EA+ D + ++    Y LG+    H     V   Q +IG E + Q L   G  PD ++ 
Sbjct: 209 ISEAVED-AATHADTKYALGSVLN-H-----VLHHQTIIGLEVEKQ-LAAIGEKPDYLVG 260

Query: 230 CVGGGSNAIGMFADFINETNVG----LIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAP 285
           CVGGGSN  G+   F+     G     I VEP             L  G+    +G  A 
Sbjct: 261 CVGGGSNFAGLVLPFLPRKLSGEAIRFIAVEPKACPT--------LTRGQFRYDYGDVAQ 312

Query: 286 M-----MQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLC 340
           +     M T       +   + GL +    P    L + G  D  +    E  +A +   
Sbjct: 313 LTPLLKMHTLGHAFMPAPIHAGGLRYHGGAPIVCNLANEGLIDATAYFQTECFDAARLFL 372

Query: 341 LHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKAR 394
             EG +PA E+SHA+  A++  ++    E ++ +  SG G  D+ +    L+ +
Sbjct: 373 RTEGFLPAPETSHAIKGAIETAKKAKPGENVVFL-YSGHGLLDLASYDAFLQGK 425


>UniRef50_A8M857 Pyridoxal-5'-phosphate-dependent protein beta subunit n=3
           Tax=Actinomycetales RepID=A8M857_SALAI
          Length = 447

 Score = 95.1 bits (235), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 110/374 (29%), Positives = 162/374 (43%), Gaps = 49/374 (13%)

Query: 47  DLLKNYAGRPTALTKCQNI--TAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKT 104
           D  ++Y  RPT L +        G    +++K E     G+HK    L QA   +  G  
Sbjct: 62  DAYRSY--RPTPLWRATRFETAVGAKVPIWVKYEGGNISGSHKLTTALAQAYYYRNAGAR 119

Query: 105 EIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSA 164
           E++  TGAGQ G A A A AL GL+C ++M    + R+      M+++GAEV    SG+ 
Sbjct: 120 ELVTGTGAGQWGTALAAACALFGLRCTVFMVGSSLSRKPYRGVLMKMLGAEVQASPSGTT 179

Query: 165 -----------TLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETK 213
                      +L  A  EA+ +++   + A + +G+        T     Q +IG E  
Sbjct: 180 RVSRSAQGQGNSLSLAIGEAV-EYAAGRDGAAFCIGSGE------TYSILHQSVIGIEAG 232

Query: 214 AQILEREGRLPDAVIACVGGGSNAIGMFADFINE-----TNVGLIGVEPGGHGIETGEHG 268
            Q+ E+ G + DAV+ CVG GSN  G+   F  E     TN  L+        +      
Sbjct: 233 EQLQEQGGEV-DAVVGCVGAGSNFGGVALPFHAEARSQGTNAPLL--------VAAESSS 283

Query: 269 APLKHGRVGIYFGMKAPMMQTEDGQ----IEESYSI----SAGLDFPSVGPQHAYLNSTG 320
           AP      GIY   +     T   +    I  SYSI    SAGL F       + L  +G
Sbjct: 284 APKL--TQGIYAYDRTDSTDTSPLEAMYTIGSSYSIPDSHSAGLRFHGAAKLVSALRHSG 341

Query: 321 RADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQL---LVVNLS 377
               ++I    ALEA +     E ++PA ES HALA A ++     D  Q    ++V +S
Sbjct: 342 HVAAMAIDQVVALEAGQRFATTEMVVPAPESGHALAAAAQLATTGADDLQASHGVLVCVS 401

Query: 378 GRGDKDIFTVHDIL 391
           G G  D+     +L
Sbjct: 402 GHGYLDLSAYQQLL 415


>UniRef50_C7GZ56 Tryptophan synthase beta chain 2 n=3 Tax=Bacteria
           RepID=C7GZ56_9FIRM
          Length = 461

 Score = 92.4 bits (228), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 110/365 (30%), Positives = 149/365 (40%), Gaps = 43/365 (11%)

Query: 47  DLLKNYAGRPTALTKCQNITAGTNT--TLYLKREDLLHGGAHKTNQVLGQALLAKRMGKT 104
           DL + Y  RP+ L +  ++    +T   +Y K E     G+HK N  + Q   AK  G  
Sbjct: 78  DLYRQY--RPSPLCRAYHLEKALDTPAKIYYKFEGNNTAGSHKLNSSIPQVYYAKEQGLK 135

Query: 105 EIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIP-----V 159
            +  ETGAGQ G A A A    GL   +YM     E +      +   G +VIP      
Sbjct: 136 GVTTETGAGQWGTALAEACGFFGLDLIVYMVRVSYEGKPFRRNIIETFGGKVIPSPSDTT 195

Query: 160 HSGSATLK---DACNEALRDWSGSYETA------HYMLGTAAGPHPYPTIVREFQRMIGE 210
            SG A LK   D+        S + ETA       Y LG+          V   Q +IG 
Sbjct: 196 ESGRAILKMDPDSPGSLGTAISEAVETASKDPGFRYTLGSVLNQ------VALHQSIIGM 249

Query: 211 ETKAQILEREGRLPDAVIACVGGGSNAIGMFADFIN-----ETNVGLIGVEPGGHGIETG 265
           E+  + ++     PD VI C GGGSN  G+ A F       E N  L+ VEP      T 
Sbjct: 250 ES-YKAMQIYDEYPDIVIGCAGGGSNLAGLIAPFARDKIQGEHNPELLAVEPS--SCPTL 306

Query: 266 EHGAPLKHGRVGIYFGMKAPM--MQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRAD 323
             G+ L         G   PM  M T   +     + + GL +  + P  + L   G   
Sbjct: 307 TRGSYLYDYCDA---GKITPMAKMYTLGNEFMPPATHAGGLRYHGMSPIVSKLYHDGYMK 363

Query: 324 YVSITDDEALEAFKTLCLHEGIIPALESSHALA----HALKMMRENPDKEQLLVVNLSGR 379
             S    E  EA K    +E I+PA ESSHA+      A+K   EN  K   ++  L+G 
Sbjct: 364 AKSYGQTEIFEAAKFFAKYETILPAPESSHAIKGAIDEAIKCREENTKK--TILFGLTGT 421

Query: 380 GDKDI 384
           G  D+
Sbjct: 422 GFFDM 426


>UniRef50_Q970N1 Tryptophan synthase beta chain 2 n=16 Tax=Archaea RepID=TRPB2_SULTO
          Length = 431

 Score = 92.4 bits (228), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 110/405 (27%), Positives = 167/405 (41%), Gaps = 55/405 (13%)

Query: 19  QILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNY--AGRPTALTKCQNITA--GTNTTLY 74
           Q+L   + +LE +     K PE      ++L+ Y   GRPT + + + +    G    +Y
Sbjct: 45  QVLPSKVLELEFSKERYIKIPE------EVLQRYLQVGRPTPIIRARKLEEYLGGYIKIY 98

Query: 75  LKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYM 134
           +K E   + G+HK N  L     AK      +  ETGAGQ G A ALASAL  ++  I+M
Sbjct: 99  MKMESHTYTGSHKINSALAHVYFAKLDNAKFVSTETGAGQWGSAVALASALFNIQAHIFM 158

Query: 135 GAKDVERQSPNVFRMRLMGAEVIPVHS-----GSATLKDACNEALRDWSGSYETAHYMLG 189
                  +    + M++  A+V P  S     G   L    N          E  +Y L 
Sbjct: 159 VRTSYYAKPYRRYLMQMYNAQVHPSPSEFTRYGREVLAKDPNTPGSLGIAISEAVYYALE 218

Query: 190 TAAGPHPYPTIVRE---FQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFIN 246
              G +   ++V     F+ + G E K Q +E  G  PD +I  VGGGSN   +   F+ 
Sbjct: 219 N-GGKYVVGSVVNSDILFKTIAGMEAKKQ-MEMIGEDPDYIIGVVGGGSNYAALAYPFLG 276

Query: 247 E-----------TNVGLIGVEPGGHGI------ETGEHGAPLKHGRVGIYFGMKAPMMQT 289
           E              G I V     G+      +T +    LK   +G  F + AP+   
Sbjct: 277 EELRKGKVRRKYIASGAIEVPKMTKGVYKYDYPDTAKILPMLKMYTIGSDF-IPAPVY-- 333

Query: 290 EDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPAL 349
                      + GL + +V P  + L   G       + +EA    K     EG +PA 
Sbjct: 334 -----------AGGLRYHAVAPTLSLLMYKGIVQARDYSQEEAFSWAKLFSQIEGWVPAP 382

Query: 350 ESSHALAHALKMMRENPDK---EQLLVVNLSGRGDKDIFTVHDIL 391
           E+SHAL   LK + E   K   ++ ++++ SG G  D+    D+L
Sbjct: 383 ETSHALP-ILKEIVEEAKKSGEKKTVLISFSGHGLLDLANYADVL 426


>UniRef50_O05626 Tryptophan synthase beta subunit (Fragment) n=1 Tax=Streptomyces
           flavovirens RepID=O05626_9ACTO
          Length = 107

 Score = 88.6 bits (218), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 43/80 (53%), Positives = 59/80 (73%), Gaps = 1/80 (1%)

Query: 307 PSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENP 366
           P +GP+HAYL   GR +Y ++TDD A+ A + L   EGIIPA+ES+HALA AL++ +E  
Sbjct: 1   PGIGPEHAYLKDVGRGEYRAVTDDAAMRALRLLSRTEGIIPAIESAHALAGALEVGKELG 60

Query: 367 DKEQLLVVNLSGRGDKDIFT 386
             + L++VNLSGRGDKD+ T
Sbjct: 61  -TDGLILVNLSGRGDKDMDT 79


>UniRef50_A8HUC1 Tryptophan synthase beta subunit (Fragment) n=1 Tax=Bacillus
           subtilis subsp. subtilis RepID=A8HUC1_BACSU
          Length = 126

 Score = 88.6 bits (218), Expect = 4e-16,   Method: Composition-based stats.
 Identities = 44/85 (51%), Positives = 57/85 (67%), Gaps = 1/85 (1%)

Query: 21  LMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTN-TTLYLKRED 79
           LM  L +++ AF   + DP F+ ++  LLK+Y+GRPTALT    +T       +YLKRED
Sbjct: 2   LMQPLDEIQTAFKQIKDDPAFREEYYKLLKDYSGRPTALTYADRVTEYLGGAKIYLKRED 61

Query: 80  LLHGGAHKTNQVLGQALLAKRMGKT 104
           L H G+HK N  LGQALLAK+MGKT
Sbjct: 62  LNHTGSHKINNALGQALLAKKMGKT 86


>UniRef50_Q44051 Transposon Mu dl-R insertion site. (Fragment) n=1 Tax=Escherichia
          coli RepID=Q44051_ECOLX
          Length = 45

 Score = 87.0 bits (214), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 40/40 (100%), Positives = 40/40 (100%)

Query: 1  MTTLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPE 40
          MTTLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPE
Sbjct: 6  MTTLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPE 45


>UniRef50_Q13AA2 Tryptophan synthase, beta chain-like n=7 Tax=Bacteria
           RepID=Q13AA2_RHOPS
          Length = 454

 Score = 85.5 bits (210), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 106/395 (26%), Positives = 161/395 (40%), Gaps = 53/395 (13%)

Query: 21  LMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNI--TAGTNTTLYLKRE 78
           L P    L+E  V+  +  +  A   D+ + +  RP+ L + + +    GT   +Y K E
Sbjct: 49  LFPMELILQE--VATDRYIDIPAPVRDVFRMW--RPSPLVRARRLEQALGTPAKIYYKYE 104

Query: 79  DLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGL-----KCRIY 133
            +   G+HK N  + QA   K+ G  ++  ETGAGQ G + A A +L GL     + RI 
Sbjct: 105 GVSPAGSHKPNTAVPQAWYNKQAGIKKLSTETGAGQWGSSLAFAGSLFGLDVLVFQVRIS 164

Query: 134 MGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKD----------ACNEALRDWSGSYET 183
              K   R     +  R + +      SG + L            A +EA+ + +     
Sbjct: 165 YDQKPYRRALMETYGARCIASPSNETESGRSILAQTPDSPGSLGIAISEAV-EVAAKNPD 223

Query: 184 AHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFAD 243
             Y LG+          V   Q +IGEE   Q  E  G  PD +I C GGGSN  G+   
Sbjct: 224 IKYALGSVL------NHVMLHQTIIGEEAIKQC-EMAGDDPDVIIGCAGGGSNFAGLAFP 276

Query: 244 FIN-----ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKA---PMMQ--TEDGQ 293
           FI           +I VEP             L  G+    FG  +   P+M+  T    
Sbjct: 277 FIGLQLRGGRRRRIIAVEPAA--------CPSLTRGKYAYDFGDTSHLTPLMKMHTLGST 328

Query: 294 IEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSH 353
                  + GL +  +G   ++    G  +  +    +  EA      +EGI+PA ES+H
Sbjct: 329 FMPPGFHAGGLRYHGMGAMVSHAYELGLIEARAYHQVKCFEAGVQFARNEGIVPAPESTH 388

Query: 354 ----ALAHALKMMRENPDKEQLLVVNLSGRGDKDI 384
               A+  AL+   E   K + ++ NLSG G  D+
Sbjct: 389 AVRCAIDEALRCKEEG--KSETILFNLSGHGHFDM 421


>UniRef50_C1SGJ4 Tryptophan synthase beta chain n=1 Tax=Denitrovibrio acetiphilus
          DSM 12809 RepID=C1SGJ4_9BACT
          Length = 106

 Score = 84.7 bits (208), Expect = 6e-15,   Method: Compositional matrix adjust.
 Identities = 36/83 (43%), Positives = 52/83 (62%)

Query: 8  YFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITA 67
          ++G +GG +VP+ L+PA+  LE  F   + D +F  +  +L   YAGRPT + K QN++ 
Sbjct: 6  FYGRYGGQFVPETLIPAIDDLEAKFEELKDDAKFNEELKELFTKYAGRPTPVYKAQNLSD 65

Query: 68 GTNTTLYLKREDLLHGGAHKTNQ 90
               +YLKREDL+H GAHK N 
Sbjct: 66 KYGCEIYLKREDLMHTGAHKLNN 88


>UniRef50_C6TEW3 Putative uncharacterized protein (Fragment) n=1 Tax=Glycine max
           RepID=C6TEW3_SOYBN
          Length = 238

 Score = 60.1 bits (144), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 34/109 (31%), Positives = 53/109 (48%), Gaps = 2/109 (1%)

Query: 55  RPTALTKCQNITAGTNTT--LYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGA 112
           RPT L + + +    +T   +Y K E +   G+HK N  + QA    + G   ++ ETGA
Sbjct: 127 RPTPLIRAKRLEKLLDTPARIYYKYEGVSPAGSHKPNSAVPQAWYNLQAGVKNVVTETGA 186

Query: 113 GQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS 161
           GQ G A A A ++ GL C ++      + +      M+  GA+V P  S
Sbjct: 187 GQWGSALAFACSIFGLGCEVWQVRASYDSKPYRRLMMQTWGAKVHPSPS 235


>UniRef50_B9SZR5 Tryptophan synthase beta chain, putative n=1 Tax=Ricinus communis
           RepID=B9SZR5_RICCO
          Length = 212

 Score = 53.9 bits (128), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 28/80 (35%), Positives = 40/80 (50%), Gaps = 2/80 (2%)

Query: 55  RPTALTKCQNITA--GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGA 112
           RPT L + + +     T   +Y K E +   G+HK N  + Q     + G   ++ ETGA
Sbjct: 129 RPTPLIRAKRLEKLLDTPAKIYYKYEGVSPAGSHKPNTAVPQVFYNAQQGIKNVVTETGA 188

Query: 113 GQHGVASALASALLGLKCRI 132
           GQ G + A A +L GL C I
Sbjct: 189 GQWGSSLAFACSLFGLGCEI 208


>UniRef50_D1C1V4 Threonine synthase n=3 Tax=Bacteria RepID=D1C1V4_SPHTD
          Length = 415

 Score = 51.2 bits (121), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 72/277 (25%), Positives = 112/277 (40%), Gaps = 55/277 (19%)

Query: 127 GLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHY 186
           GL   ++M A   E   P     R  GA V  V      L + C   +R  +G+     +
Sbjct: 151 GLDAYVFMPADTPE---PMKAECRAYGARVFLVIG----LINDCGRVVR--AGAEARGWF 201

Query: 187 MLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFIN 246
            + T   P+       E ++ +G E   Q+     RLPDA++   GGG+  +GM+  F  
Sbjct: 202 DVSTLKEPY-----RAEGKKTMGLELAEQL---GWRLPDAIVYPTGGGTGIVGMWKAFDE 253

Query: 247 ETNVGLIGVE-------------PGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQ 293
              +GLIG E             P     E GE  A L  G   +  G++ P+   +   
Sbjct: 254 LEQLGLIGSERPRMIVVQSEGCAPIVRAFEQGERHAQLWEGAATVAPGIRVPVAIGD--- 310

Query: 294 IEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSH 353
               Y I   LD        A   S G A  ++++D+E LE  +    HEG+  + E+  
Sbjct: 311 ----YLI---LD--------AVRQSGGTA--ITVSDEELLEGMRLAATHEGLFVSPEAGA 353

Query: 354 ALAHALKMMREN----PDKEQLLVVNLSGRGDKDIFT 386
            +A A +++RE      D E +L    +G    D+ T
Sbjct: 354 VVAAA-RLLRERGVLGQDDEVVLFATGAGLKHTDLVT 389


>UniRef50_D1BQL6 Cysteine synthase n=9 Tax=Firmicutes RepID=D1BQL6_VEIPT
          Length = 304

 Score = 45.8 bits (107), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 80/312 (25%), Positives = 123/312 (39%), Gaps = 57/312 (18%)

Query: 70  NTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK---TEIIAETGAGQHGVASALASALL 126
           NT +Y+K E    GG+ K   VLG    AK  G+     II E  +G  G+A A+  A+L
Sbjct: 22  NTNIYVKLEKYNVGGSVKDRAVLGMLQAAKEQGRIHENSIIVEATSGNTGIALAMVGAIL 81

Query: 127 GLKCRIYMG-AKDVERQSPNVFRMRLMGAEVI--PVHSGSATLKDACNEALRDWSGSYET 183
            +K  I M  +   ER+      ++  GA++I  P  +G     +  NE L  +  ++  
Sbjct: 82  HIKTVIIMPESMSKERRE----LIKAYGAQLILTPKETGMKGALERANEILAKYPNAFTL 137

Query: 184 AHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFAD 243
             ++    A P  +        R  G E   Q+        D  IA +G G    G+   
Sbjct: 138 GQFV--NPANPDMH-------YRTTGNEIVEQVPNV-----DVFIAGIGTGGTFTGVTRR 183

Query: 244 FINET-NVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISA 302
                 N+  I VEP G    T   G P K   +G  F             I E++  S 
Sbjct: 184 LKEHNPNLKAIAVEPAGSPAITEGKGGPHKIQGIGAGF-------------IPENFDQSL 230

Query: 303 GLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMM 362
            +D    G Q             +++D+EA    +T     GI   L +  A+  A ++ 
Sbjct: 231 -MD----GVQ-------------TVSDEEAFSEVQTFMRESGISIGLSAGAAIVAAKRIA 272

Query: 363 RENPDKEQLLVV 374
           RE P K  ++V+
Sbjct: 273 REEP-KANIVVI 283


>UniRef50_A3DKP7 L-threonine synthase n=2 Tax=Desulfurococcaceae RepID=A3DKP7_STAMF
          Length = 423

 Score = 45.8 bits (107), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 61/220 (27%), Positives = 101/220 (45%), Gaps = 33/220 (15%)

Query: 187 MLGTAAGPHPYPTI--VREFQRMIGEETKA-QILEREGR-LPDAVIACVGGGSNAIGMFA 242
           +L    G +P P+      +Q + G +T A +I+E+ G  +PD V    G  S   G++ 
Sbjct: 194 LLAEKYGFYPSPSFGPFNPYQ-IEGPKTIAMEIVEQLGWDVPDQVFVPTGAASLLTGVYN 252

Query: 243 DFINETNVGLIGVEPGGHGIET-GEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEE----S 297
            F +  NVG I   P    ++  G H  P           ++A M + +  +I+      
Sbjct: 253 GFRDWNNVGWINKYPRMVAVQPEGNH--PF----------VRAWMEKADPNKIKPWEKPP 300

Query: 298 YSISAGLD--FPSVGPQ--HAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSH 353
            +I+ GL+  FP  G     A  N+ G    V ++D+E LEA K L   EG+      + 
Sbjct: 301 ETIATGLEDTFPWDGDAGLRALYNTNGYG--VVVSDEEILEAMKLLASLEGLFAEPSGAA 358

Query: 354 ALAHALKMMRENP-DKEQLLVVNLSGRGDKDIFTVHDILK 392
            LA  +K + +   D+++ +VV ++G G KD     DI+K
Sbjct: 359 GLAGLIKALEDGKVDRDETIVVLVTGHGLKD----PDIVK 394


>UniRef50_Q6C6D8 YALI0E10307p n=1 Tax=Yarrowia lipolytica RepID=Q6C6D8_YARLI
          Length = 329

 Score = 45.8 bits (107), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 84/351 (23%), Positives = 140/351 (39%), Gaps = 80/351 (22%)

Query: 73  LYLKREDLLHGGAHKT---NQVLGQALLAKRMGKTEI--IAETGAGQHGVASALASALLG 127
           +YLK E+L   G+ K+    QV+  AL +      +   +  +  G  G+A+A+ S L G
Sbjct: 24  VYLKMENLQPSGSFKSRGMTQVISDALDSDPQASLDTLHVCSSSGGNAGLAAAVTSRLNG 83

Query: 128 LKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGS-----YE 182
           + C + +      R    V ++R  GAEVI VH              + WS +      E
Sbjct: 84  VACTVVVPESTKPRM---VEKLRAAGAEVI-VHG-------------KHWSEANDFLQKE 126

Query: 183 TAHYMLGTAAGP---HPY--PTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNA 237
               +  T   P   HP+  P + +    +I E      + ++G  PDAV+  VGGG   
Sbjct: 127 EMPRLEKTGKTPIYCHPFDAPAVWKGNSTLIDE------IIKQGITPDAVVCSVGGG--- 177

Query: 238 IGMFADFI-----NETNVGLIGVEPGG-----HGIETGEHGAPLKHGRVGIYFGMKAPMM 287
            G+F   +     ++ N  +I VE  G       ++ GE         +    G     +
Sbjct: 178 -GLFNGVVEGLKRHKLNCPVIVVETNGADALSRSLQKGEQVTLPGITSIATSLG----AV 232

Query: 288 QTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGII- 346
           +  D   E + +      +P+V                 ++DD+A+ A       + II 
Sbjct: 233 RVADKTFENAQT------YPTVS--------------AVVSDDDAVSALVEYAETKQIIV 272

Query: 347 -PALESSHALAHALK-MMRENPDKEQLLVV-NLSGRGDKDIFTVHDILKAR 394
            PA  +S A+  ALK ++   PD   ++V+   S  G  DI      L+A+
Sbjct: 273 EPACGASLAVLPALKDLVDLKPDSNVVVVLCGGSATGISDIAQFKKDLEAK 323


>UniRef50_B9JX06 Threonine dehydratase n=16 Tax=Alphaproteobacteria
           RepID=B9JX06_AGRVS
          Length = 416

 Score = 45.8 bits (107), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 50/188 (26%), Positives = 79/188 (42%), Gaps = 20/188 (10%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE-IIAETGAGQH 115
           T L   ++++   N  +YLKREDL    ++K             +G+ + I     AG H
Sbjct: 20  TPLQLSEHLSTLFNANIYLKREDLTPVRSYKVRGAYNFFRKVIALGQIDKIFVCASAGNH 79

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
               A A    G+   ++M     +++   + + R  GAE I +      + D C +A R
Sbjct: 80  AQGFAFACRHFGVHGVVFMPVTTPQQK---IDKTRKFGAEFITIRL-VGDIFDQCYKAAR 135

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEET-KAQILER--EGRLPDAVIACVG 232
           D+    +      G    P  +  I+       G+ T  A+ILE+  E   PD VI  VG
Sbjct: 136 DYVEEAD------GLMVPPFDHADIIE------GQATVAAEILEQLSEEVTPDLVIMPVG 183

Query: 233 GGSNAIGM 240
           GG  + GM
Sbjct: 184 GGGLSAGM 191


>UniRef50_UPI0001903713 tryptophan synthase subunit beta n=1 Tax=Rhizobium etli Brasil 5
          RepID=UPI0001903713
          Length = 69

 Score = 45.1 bits (105), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 20/49 (40%), Positives = 31/49 (63%)

Query: 9  FGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPT 57
          FG +GG +V + LMP +  L++ +  A+ DP FQA+   L  +Y GRP+
Sbjct: 20 FGIYGGRFVAETLMPLILDLQDEWNKAKTDPAFQAELKHLGAHYIGRPS 68


>UniRef50_A2ETD5 Threonine synthase family protein n=1 Tax=Trichomonas vaginalis
           RepID=A2ETD5_TRIVA
          Length = 429

 Score = 44.7 bits (104), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 80/325 (24%), Positives = 127/325 (39%), Gaps = 31/325 (9%)

Query: 73  LYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRI 132
           L++K E      + K        + AK +GKT ++    +G    A++   A LGLK  I
Sbjct: 96  LWIKDEGREPTASLKDRASALVCVKAKELGKT-VVTTASSGNAAAATSCMCACLGLKPVI 154

Query: 133 YMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAA 192
           ++ A         V + RL GA V  V        +A   A + +S    +  +   T  
Sbjct: 155 FVPA---HAPPAKVLQNRLYGATVFLVEGVYDRAVEAAMGAAKKYSWYNRSTGFNPYTID 211

Query: 193 GPHPYPTIVREFQRMIG-----EETKAQILEREGRL-----PDAVIACVGGGSNAIGMFA 242
           G     T+  E    +G     EETK +     G+L     PDA++  VG G+   G+  
Sbjct: 212 GKK---TVSFEICEQLGGILCPEETKGEC--SWGKLGKFVAPDAIVVSVGDGNIISGVHK 266

Query: 243 DFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISA 302
                   GLI   P   G++          G   +Y       +   +  + E  +++ 
Sbjct: 267 GLKELFAAGLIEKVPKIIGVQA--------EGSNSVYVCWSQ-KIDPVNMPVCEGSTLAD 317

Query: 303 GLDFPSVG-PQHAYLNST-GRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALK 360
            +  P+   P  A+  +T     YV +TD+E L A  T+    GI P   ++   A   K
Sbjct: 318 SISCPTPNDPIRAFRAATETNGAYVQVTDEEILAAIPTMARATGIFPEPAAAAGFAGIFK 377

Query: 361 MMRENPDKEQLLVVNLS-GRGDKDI 384
             ++   K    VV +S G G KDI
Sbjct: 378 AEQQGYLKPGEKVVMISTGNGLKDI 402


>UniRef50_B0VGY7 Putative threonine synthase n=1 Tax=Candidatus Cloacamonas
           acidaminovorans RepID=B0VGY7_9BACT
          Length = 392

 Score = 44.3 bits (103), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 77/325 (23%), Positives = 136/325 (41%), Gaps = 41/325 (12%)

Query: 66  TAGTNTTLYLKREDLLHGGAHK---TNQVLGQALLAKRMGKTEII-AETGAGQHGVASAL 121
           TA   T L++K + L   G++K   +  V+  AL   + G  EI+ A TG     +A   
Sbjct: 96  TASNYTKLWIKFDGLNPSGSYKDRASQLVVADAL---QKGIKEIVTASTGNAACSLACLG 152

Query: 122 ASALLGLKCRIYMGAKDVERQSP--NVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSG 179
           ASA  GLK  I+       + +P   + ++++  AE+   H    +  DA   AL     
Sbjct: 153 ASA--GLKVVIF-----APQNAPPAKLIQIQVHNAEL---HKIDGSYDDAFKAALE---- 198

Query: 180 SYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIG 239
            Y   H  +    G HP   +  + ++  G E   Q      ++PD ++  VG G    G
Sbjct: 199 -YTKTHNCMCRNTGYHP---LTIDGKKSAGIEIYVQ---NGYKVPDWIVIPVGDGVILTG 251

Query: 240 MFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYS 299
           ++  F++    G+    P    ++     A   +   GIY   + P+   +  +++    
Sbjct: 252 IYKAFLDLKKAGITEKMPHLLCVQAESSDAITSYWETGIYHDAENPITIADSIKVK---- 307

Query: 300 ISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHAL 359
            +  L   SV    A   + G+   + ++D E  EA   L    G+     SS  LA   
Sbjct: 308 -TPALAHWSV---KALKETDGKC--IRVSDKEIQEAQLELAKETGVFSEPSSSATLAGLK 361

Query: 360 KMMRENPDKE-QLLVVNLSGRGDKD 383
           K++  +  K+ + +V+ ++G G KD
Sbjct: 362 KVVNHSWLKDAKDIVLLITGHGLKD 386


>UniRef50_P14552 Tryptophan synthase beta chain (Fragment) n=9 Tax=Bacteria
           RepID=TRPB_KLEAE
          Length = 19

 Score = 44.3 bits (103), Expect = 0.008,   Method: Composition-based stats.
 Identities = 19/19 (100%), Positives = 19/19 (100%)

Query: 379 RGDKDIFTVHDILKARGEI 397
           RGDKDIFTVHDILKARGEI
Sbjct: 1   RGDKDIFTVHDILKARGEI 19


>UniRef50_C6A2V6 Threonine dehydratase n=1 Tax=Thermococcus sibiricus MM 739
           RepID=C6A2V6_THESM
          Length = 321

 Score = 43.1 bits (100), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 53/205 (25%), Positives = 86/205 (41%), Gaps = 22/205 (10%)

Query: 55  RPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQ 114
           R T L     ++   N  +YLK E+    G+ K   V  + L      K   I    +G 
Sbjct: 20  RETPLDYSPFLSQKGNANVYLKLENFQLTGSFKIRGVFNKLLSLSEEEKKRGIVTASSGN 79

Query: 115 HGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEAL 174
           HG A A AS  L L   +++     E  SP         A++  +   +  L+   N+ +
Sbjct: 80  HGAAFAYASNFLNLNGIVFLP----ENASP---------AKIQDIKQYNVELRFYGNDTV 126

Query: 175 RDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGG 234
           +    +   A         P+  P ++   Q  IG E + Q+    G++ DAV+  VGGG
Sbjct: 127 KTEIFARNFAEEQEMIYVPPYNDPKVIGG-QGTIGVELEKQL----GKI-DAVLVPVGGG 180

Query: 235 SNAIGMFADFINE--TNVGLIGVEP 257
               G+ A ++ E   +V +IGV+P
Sbjct: 181 GLISGI-AGYLKEKMKDVEIIGVQP 204


>UniRef50_Q58860 Probable threonine synthase n=38 Tax=Archaea RepID=THRC_METJA
          Length = 405

 Score = 43.1 bits (100), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 80/334 (23%), Positives = 131/334 (39%), Gaps = 38/334 (11%)

Query: 57  TALTKCQNITAGTNTT-LYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           T L +C N+        LY+K E     G+ K   +      A  +G  E++     G  
Sbjct: 75  TPLYRCNNLEKELGIKELYVKNEGANPTGSFKDRGMTVGVTRANELG-VEVVGCASTGNT 133

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
             + A  SA  G KC + +    V      + +    GA+VI V        D   +  +
Sbjct: 134 SASLAAYSARSGKKCIVLLPEGKV--ALGKLAQAMFYGAKVIQVKGNFDDALDMVKQLAK 191

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
                 E   Y+L +    +P+     E Q+ I  E   Q+     ++PD VI  VG   
Sbjct: 192 ------EKLIYLLNSI---NPFRL---EGQKTIAFEICDQL---NWQVPDRVIVPVGNAG 236

Query: 236 NAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHG---RVGIYFGMKAPMMQTEDG 292
           N   ++  F      G+I   P   GI+  +   P+      R       K P       
Sbjct: 237 NISAIWKGFKEFEITGIIDELPKMTGIQ-ADGAKPIVEAFRKRAKDIIPYKNP------- 288

Query: 293 QIEESYSISAGLDFPSVGPQ--HAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALE 350
              E+ + +  +  P   P+   A  +S G A+  ++TD+E +EA K L   EGI     
Sbjct: 289 ---ETIATAIRIGNPVNAPKALDAIYSSGGYAE--AVTDEEIVEAQKLLARKEGIFVEPA 343

Query: 351 SSHALAHALKMMREN-PDKEQLLVVNLSGRGDKD 383
           S+ ++A   K++ E   D+++ +V   +G G KD
Sbjct: 344 SASSIAGLKKLLEEGIIDRDERIVCITTGHGLKD 377


>UniRef50_C1PE10 Threonine dehydratase n=2 Tax=Bacillaceae RepID=C1PE10_BACCO
          Length = 350

 Score = 43.1 bits (100), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 75/293 (25%), Positives = 118/293 (40%), Gaps = 47/293 (16%)

Query: 43  AQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQAL-LAKRM 101
           A F +LL      P   +   N  AGT   LY K E+L   G+ K    L +   L    
Sbjct: 29  AAFENLLPVVHRTPLNESATFNEMAGTR--LYFKMENLQRTGSFKIRGALNKITNLTGDA 86

Query: 102 GKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSP--NVFRMRLMGAEVIPV 159
            K  +IA + AG H    A ++   GLK +IYM  K     +P   V   +  GAEV+  
Sbjct: 87  RKNGVIAAS-AGNHAQGVAFSATKQGLKAKIYMPEK-----TPLAKVLATKAYGAEVVLT 140

Query: 160 HSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILER 219
                + ++A   A+ D           +  A   HP+     +++ M G+ T A  + +
Sbjct: 141 ---GESFQEAYEAAVLDQQ---------ITGATFIHPFD----DYEVMAGQGTIALEMIQ 184

Query: 220 EGRLPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGI 278
           +    D V+  VGGG    GM     N +  + +IGV+           GAP  + R   
Sbjct: 185 QCADLDTVVIPVGGGGLIAGMACLLKNYDPKIRVIGVQ---------SEGAPAAYNR--- 232

Query: 279 YFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDE 331
           + GM        + ++E    I+ G+     G     L S    D V+++D++
Sbjct: 233 FKGMG-------NSRLEHVSGIADGILVKETGQLTFPLISKYVDDVVTVSDED 278


>UniRef50_Q04513 Threonine dehydratase biosynthetic n=34 Tax=Actinomycetales
           RepID=THD1_CORGL
          Length = 436

 Score = 43.1 bits (100), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 30/97 (30%), Positives = 41/97 (42%), Gaps = 5/97 (5%)

Query: 56  PTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           PT L  C  ++  T   +YLKREDL    ++K    L       +  +   I    AG H
Sbjct: 39  PTPLQYCPRLSEETGAEIYLKREDLQDVRSYKIRGALNSGAQLTQEQRDAGIVAASAGNH 98

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLM 152
               A     LG++ RIY     V  Q+P   R R+M
Sbjct: 99  AQGVAYVCKSLGVQGRIY-----VPVQTPKQKRDRIM 130


>UniRef50_A1KYC1 Serine dehydratase n=1 Tax=Aplysia californica RepID=A1KYC1_APLCA
          Length = 332

 Score = 42.7 bits (99), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 46/168 (27%), Positives = 65/168 (38%), Gaps = 30/168 (17%)

Query: 73  LYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRI 132
           +YLK ++L   G+ K   +          G +E +     G  G+A+A AS  LG+ C I
Sbjct: 36  VYLKLDNLQPSGSFKIRGISNMIQKGIDRGDSEHVYCASGGNAGMAAAHASKQLGIPCTI 95

Query: 133 YMGAKDVERQSPNVF--RMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGT 190
                 V + +P     R+R +GAEV  VH                  GS       L  
Sbjct: 96  V-----VPQTTPEFVNERLRNLGAEV-KVH------------------GSVYDEAKKLAV 131

Query: 191 AAGPHPYPTIVREFQRMIGEETKAQILEREGR----LPDAVIACVGGG 234
             G  P   ++  F+     E  A ++    R     PD VI CVGGG
Sbjct: 132 ELGSQPRCMLIPAFEHPDIWEGHASLINESSRQMSERPDLVITCVGGG 179


>UniRef50_A0LFH6 Cysteine synthases n=15 Tax=cellular organisms RepID=A0LFH6_SYNFM
          Length = 773

 Score = 42.4 bits (98), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 80/349 (22%), Positives = 140/349 (40%), Gaps = 65/349 (18%)

Query: 45  FNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG-- 102
           F+++L++    P  L +   +      TLY K E    GG+ K    L     A+R G  
Sbjct: 5   FSNVLESIGNTP--LIRINRLNPNPAVTLYAKLEAKNPGGSIKDRTALFMIESAERDGLL 62

Query: 103 -KTEIIAETGAGQHGVASALASALLGLKCRIYMG-AKDVERQSPNVFRMRLMGAEVIPVH 160
              +II E  +G  G+  A+ +A+ G +  + M     +ERQ      ++ +GAE++   
Sbjct: 63  THEKIIIEATSGNTGIGLAIVAAVKGYRLMLAMPETASLERQKI----LKALGAEILLTP 118

Query: 161 SGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILER- 219
               T  D   E +          +YM      P  +           G  T  +I E+ 
Sbjct: 119 GNLGT--DGAIEKVYSLVRENPDRYYM------PDQFNNPANPAAHHFG--TGPEIFEQT 168

Query: 220 EGRLPDAVIACVGGGSNAIGMFADFI-NETNVGLIGVEP-GGHGIETGEHGAPLKHGRVG 277
           EG++ + V+  +G    A+G+       +  + ++GVEP  GH ++              
Sbjct: 169 EGKV-NTVVVTLGTTGTAMGILQAMKERDPAIRVVGVEPYPGHRVQ-------------- 213

Query: 278 IYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFK 337
              G+K          ++ESY        P +  +HA          + I D++A E  +
Sbjct: 214 ---GLK---------NMKESY-------VPGIFDRHAL------DQIIHIKDEDAFEMAR 248

Query: 338 TLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFT 386
            L   EGI   + S  A+A A+++  E   +E ++V  L   GD+ + T
Sbjct: 249 RLAREEGIFTGMSSGAAMAIAVRVAEEM--REGIVVAVLPDGGDRYLST 295


>UniRef50_A8F1M7 Threonine dehydratase n=20 Tax=cellular organisms
           RepID=A8F1M7_RICM5
          Length = 346

 Score = 42.4 bits (98), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 54/191 (28%), Positives = 82/191 (42%), Gaps = 30/191 (15%)

Query: 73  LYLKREDLLHGGAHKTNQVLGQALLAKRMGKT-EIIAETGAGQHGVASALASALLGLKCR 131
           ++ K E L   GA K   VL   L  K  GK  + I     G HG+  A AS L G+K R
Sbjct: 44  IFFKVESLQKTGAFKVRGVLNHLLELKEQGKLPDKIVGYSTGNHGIGLAYASKLFGIKTR 103

Query: 132 IY--MGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLG 189
           IY  +    V++Q+   +     G EVI  ++     + A  +  + +       +YM  
Sbjct: 104 IYLPLNTSKVKQQAALYY-----GGEVIYTYTRQEAEEKAKEDEKQGF-------YYM-- 149

Query: 190 TAAGPHPYPTIVREFQRMIGEETKA-QILEREGRLPDAVIACVGGGSNAIGMF--ADFIN 246
                HP  +       + G  T   + L++    PDA+ A  GGG    G +   + I+
Sbjct: 150 -----HPSDSD----STIAGAGTLCYEALQQLDFSPDAIFASCGGGGLISGAYLAKELIS 200

Query: 247 ETNVGLIGVEP 257
            T++ LIG EP
Sbjct: 201 PTSL-LIGSEP 210


>UniRef50_Q9ZMW6 Cysteine synthase n=44 Tax=Bacteria RepID=CYSM_HELPJ
          Length = 305

 Score = 42.4 bits (98), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 60/213 (28%), Positives = 84/213 (39%), Gaps = 38/213 (17%)

Query: 70  NTTLYLKREDLLHGGAHKTNQVLGQALL-----AKRMGKTEIIAETGAGQHGVASALASA 124
            + +Y K E L  GG+ K    LGQ L+      +++  T  I E  AG  G+A AL + 
Sbjct: 28  KSAIYAKLEHLNPGGSVKDR--LGQYLIKEAFRTRKITSTTTIIEPTAGNTGIALALVAI 85

Query: 125 LLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVI--PVHSGSATLKDACNEALRDWSGSYE 182
              LK  I++  K    +   +  MR +GA VI  P   G +       E       SY 
Sbjct: 86  KHHLKT-IFVVPKKFSTEKQQI--MRALGALVINTPTSEGISGAIKKSKELAESIPDSYL 142

Query: 183 TAHYMLGTAAGPHPY-----PTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNA 237
              +       P  Y     P IV+E                 G    + +A +G G   
Sbjct: 143 PLQFE--NPDNPAAYYHTLAPEIVQEL----------------GTNLTSFVAGIGSGGTF 184

Query: 238 IGMFADFINE--TNVGLIGVEPGGHGIETGEHG 268
            GM A ++ E   N+ LIGVEP G  +  GE G
Sbjct: 185 AGM-AKYLKERIPNIRLIGVEPEGSILNGGEPG 216


>UniRef50_B6A2K1 Pyridoxal-5'-phosphate-dependent protein beta subunit n=8
           Tax=Proteobacteria RepID=B6A2K1_RHILW
          Length = 323

 Score = 42.4 bits (98), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 59/207 (28%), Positives = 81/207 (39%), Gaps = 24/207 (11%)

Query: 55  RPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQ 114
           R T L + + I       LYLK E L   GA K    L + L   R      +  + +G 
Sbjct: 22  RHTPLLRAEKIEKAVGCQLYLKPETLQITGAFKIRGALNKVLSLPREEIANGVIASSSGN 81

Query: 115 HGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEAL 174
           H    + A+ +LG+K  + +    V      +   R +GAEVI     +A          
Sbjct: 82  HAQGLSYAARILGVKVILVL---PVTTPKIKIANTRALGAEVILFDGDTAA--------- 129

Query: 175 RDWSGSYETAHYMLGTAAGPHPYPT-IVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
             W   YE A       A  H +   +V   Q  IG     +ILE    + D VI  VGG
Sbjct: 130 -RWKKVYEIAEE--NNYATIHGFEDPLVMAGQGTIG----CEILEDLDDV-DTVIVPVGG 181

Query: 234 GSNAIGMFADFINET--NVGLIGVEPG 258
           G   I   A  I ET  +V ++G EP 
Sbjct: 182 G-GLISGIATAIKETKPSVRVVGAEPA 207


>UniRef50_Q1IJB6 L-threonine synthase n=2 Tax=Bacteria RepID=Q1IJB6_ACIBL
          Length = 396

 Score = 42.4 bits (98), Expect = 0.032,   Method: Compositional matrix adjust.
 Identities = 55/197 (27%), Positives = 92/197 (46%), Gaps = 22/197 (11%)

Query: 199 TIVREFQRMIGEETKA-QILEREG-RLPDAVIACVGGGSNAIGMFADFINETNVGLIGVE 256
           + ++E  R+ G++T   ++ E+ G  LPDA+I   GGG   +GM+  F     +G IG +
Sbjct: 190 STLKEPFRVEGKKTMGYEVAEQLGWELPDAIIYPTGGGVGLLGMWKAFEEMEQLGWIGSK 249

Query: 257 PGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQI-EESYSISAGLDFPSVGPQ--- 312
                       AP+          +KA     E  ++ +++++ +AGL  P        
Sbjct: 250 RPKMICAQATGCAPV----------VKAWEEHRETMEMWKDAHTSAAGLRVPKPYADREI 299

Query: 313 -HAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRE---NPDK 368
            HA   S G A  V++TDDE + AF +    EG+  A E + ALA   K++      P++
Sbjct: 300 LHAMKASGGTA--VAVTDDEIMAAFSSWAREEGVFAAPEGAAALAAYWKLIESGYLRPEE 357

Query: 369 EQLLVVNLSGRGDKDIF 385
           + +L    SG    D+F
Sbjct: 358 KVVLFNTGSGLKYIDVF 374


>UniRef50_B9L1Z4 Threonine synthase n=1 Tax=Thermomicrobium roseum DSM 5159
           RepID=B9L1Z4_THERP
          Length = 411

 Score = 42.4 bits (98), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 53/189 (28%), Positives = 92/189 (48%), Gaps = 20/189 (10%)

Query: 199 TIVREFQRMIGEETKA-QILEREG-RLPDAVIACVGGGSNAIGMFADFINETNVGLIGVE 256
           + +RE  R  G++T   +++E+ G RLPD ++   GGG+  +GM   F     +GL+   
Sbjct: 205 STLREPYRAEGKKTMGFELVEQLGWRLPDVIVYPTGGGTGIVGMEKAFAELAALGLLAGS 264

Query: 257 PGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFP-SVGPQ--H 313
                I   E  APL        F   A   +  +G    + +I+ GL  P ++G +   
Sbjct: 265 RARFVIVQPEGCAPLVRA-----FHEGATRARPWEG----AQTIAPGLRVPATIGDELVL 315

Query: 314 AYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMREN----PDKE 369
           A + ++G    V+++D E LE  + L   EG++ + E+   +A A++ +R N    PD E
Sbjct: 316 AAVRASG-GTAVAVSDQELLEGTRILATDEGVLVSPEAGATVA-AVRQLRANGWLAPDAE 373

Query: 370 QLLVVNLSG 378
            +L +  SG
Sbjct: 374 VVLFLTGSG 382


>UniRef50_A3ERN7 Cysteine synthase n=2 Tax=Leptospirillum sp. Group II
           RepID=A3ERN7_9BACT
          Length = 312

 Score = 42.0 bits (97), Expect = 0.042,   Method: Compositional matrix adjust.
 Identities = 79/333 (23%), Positives = 127/333 (38%), Gaps = 56/333 (16%)

Query: 49  LKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEI-- 106
           L    GR T L   +++T G +  +++K E    GG+ K          A+R G+     
Sbjct: 12  LDQLIGR-TPLVALESMTRGLDRVVWVKLESRNLGGSVKDRPARYMVEQAERNGELAPGG 70

Query: 107 -IAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEV--IPVHSGS 163
            I E  +G  G+A A    L G    I M  + V ++   V+ ++ +GAEV   P   G 
Sbjct: 71  RIVEATSGNTGIALAQIGVLKGYPVVIVM-PEGVSQE--RVYHLKALGAEVELTPARDGM 127

Query: 164 ATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRL 223
           A         L +  GS+    +     A P  +        R  G E    IL++ GRL
Sbjct: 128 AGAIRRAETLLSERPGSFMPRQFE--NPANPESH-------YRTTGPE----ILDQLGRL 174

Query: 224 PDAVIACVGGGSNAIGMFADFINETN--VGLIGVEPGGHGIETGEHGAPLKHGRVGIYFG 281
           PD  +A + G    I     F+ E +  V + G+EP    + +G    P +   +G  F 
Sbjct: 175 PDGFVAGI-GTGGTITGVGRFLRERHEAVRIWGLEPASSAVLSGSSPGPHRIQGIGAGFV 233

Query: 282 MKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCL 341
            K  + ++   +IE                               I D  A+E  + L  
Sbjct: 234 PKI-LDRSVCDKIE------------------------------PIDDRTAIETMRRLTR 262

Query: 342 HEGIIPALESSHALAHALKMMRENPDKEQLLVV 374
            EGI+  + S   +A AL + R  P    ++ +
Sbjct: 263 EEGIMAGISSGANVAGALLLARTLPPGSHVVTI 295


>UniRef50_Q2L695 Aspartate racemase n=3 Tax=Coelomata RepID=Q2L695_ANABR
          Length = 338

 Score = 42.0 bits (97), Expect = 0.043,   Method: Compositional matrix adjust.
 Identities = 60/243 (24%), Positives = 99/243 (40%), Gaps = 36/243 (14%)

Query: 35  AQKDPEFQAQFNDLLKNYAGRP---------TALTKCQNITAGTNTTLYLKREDLLHGGA 85
           A K P+F+    D+ K Y             T+ T  + + +      Y K E+L   G+
Sbjct: 2   ASKIPQFEVTVTDIKKAYDRISKHILYTPVFTSPTFDRMVGSKAGRQFYFKAENLQKTGS 61

Query: 86  HKTNQVLGQALLA-KRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSP 144
            K    L   L A +R      +    +G HG A A AS   G+KC +      V + +P
Sbjct: 62  FKARGALNAILCALEREPSLAGVVTHSSGNHGQALAWASKRAGVKCCVV-----VPKTAP 116

Query: 145 NVF--RMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVR 202
            V    M   GAEV+       + K+ C E L    G               + Y +   
Sbjct: 117 QVKFDAMENYGAEVVKCEPNPTSRKETC-EGLAKSRG---------------YKYISSSD 160

Query: 203 EFQRMIGEETKA-QILEREGRLPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGH 260
           ++  + G+ T A ++L+++  L DA++  V  G  A G+     N ++++ +  VEP G 
Sbjct: 161 DYDVIAGQGTIALELLQQQPDL-DAILVSVSAGGMASGICVYTKNTKSDLKVFLVEPEGK 219

Query: 261 GIE 263
            +E
Sbjct: 220 MLE 222


>UniRef50_B4AUD2 Threonine synthase, putative n=23 Tax=Francisella
           RepID=B4AUD2_FRANO
          Length = 598

 Score = 42.0 bits (97), Expect = 0.044,   Method: Compositional matrix adjust.
 Identities = 42/164 (25%), Positives = 70/164 (42%), Gaps = 11/164 (6%)

Query: 222 RLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFG 281
           ++PD VI  +G G+N    +  F     +G I   P   G+++ E     +         
Sbjct: 220 QVPDEVIIPIGCGTNMTAYYKGFCEYKELGFINSLPKLTGVQSTEADTLAR--------A 271

Query: 282 MKAPMMQTEDGQIEESYSISAGLDFPSVGPQHA-YLNSTGRADYVSITDDEALEAFKTLC 340
            +    + E  +   + + +  + +P  G +    + STG  +  ++TD + LEA   L 
Sbjct: 272 YQKNQNRIEPLKTANTIATAIAVPYPIDGDKAIDAIYSTG-GESTAVTDMKMLEAQYLLS 330

Query: 341 LHEGIIPALESSHALAHALKMMRE-NPDKEQLLVVNLSGRGDKD 383
             EG+   L S+  +AH LK   E    K   +V  LSG G KD
Sbjct: 331 TKEGLFVELASASTIAHLLKKYEEGRLQKGSTVVCVLSGEGLKD 374


>UniRef50_Q3KMJ4 Tryptophan synthase beta chain n=1 Tax=Chlamydia trachomatis
          A/HAR-13 RepID=Q3KMJ4_CHLTA
          Length = 62

 Score = 41.6 bits (96), Expect = 0.056,   Method: Composition-based stats.
 Identities = 18/53 (33%), Positives = 33/53 (62%)

Query: 12 FGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQN 64
          FGG ++P+ L+  ++ L+  +   +    F ++ + +LKNYAGR T LT+ +N
Sbjct: 8  FGGAFLPEELLAPIQNLKAEWEILKTQQSFLSELDCILKNYAGRQTPLTEVKN 60


>UniRef50_D0LAQ5 Threonine dehydratase n=6 Tax=Actinomycetales RepID=D0LAQ5_GORB4
          Length = 457

 Score = 41.6 bits (96), Expect = 0.057,   Method: Compositional matrix adjust.
 Identities = 61/213 (28%), Positives = 96/213 (45%), Gaps = 34/213 (15%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEI---IAETGAG 113
           T L  C  I+A T   ++LKREDL    + ++ ++ G   +  ++ ++E+   +    AG
Sbjct: 34  TPLEACPRISASTGAQIHLKREDL---QSVRSYKIRGAYNVMAQLSRSELDRGVVAASAG 90

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLM--GAEVIPVHSGSATLKDACN 171
            H    A A   +G+  RIY     V   +P   R R+   G E + + +   T   A  
Sbjct: 91  NHAQGVAYACRTMGVHGRIY-----VPTTTPKQKRDRISWHGGEFVELLAVGDTYDAAAA 145

Query: 172 EALRDWSGSYETAHYMLGTAAGPHPYPTIVREF---QRMIGEETKA-QILEREGRLPDAV 227
            A  D          +L T A      T +  F   +   G+ T A +I+++ GR+PD V
Sbjct: 146 AAQAD----------VLRTGA------TWIHAFDDPRTAAGQGTIAFEIVDQLGRVPDVV 189

Query: 228 IACVGGGSNAIGMFADF-INETNVGLIGVEPGG 259
           +A VGGG    GM   F     +V ++GVEP G
Sbjct: 190 VAPVGGGGCLAGMVTYFRARRPDVAIVGVEPTG 222


>UniRef50_B2KE33 Threonine synthase n=1 Tax=Elusimicrobium minutum Pei191
           RepID=B2KE33_ELUMP
          Length = 416

 Score = 41.2 bits (95), Expect = 0.061,   Method: Compositional matrix adjust.
 Identities = 68/284 (23%), Positives = 118/284 (41%), Gaps = 30/284 (10%)

Query: 105 EIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSA 164
           +IIA+   G    + A  +A L +K  ++   KD     P + ++ + GA+V  V     
Sbjct: 129 DIIADASTGNASDSLACLTAGLDIKTIVFT-TKDAPY--PKLTQLFVYGADVFTVDGTYD 185

Query: 165 TLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLP 224
              + C +A+ ++ G Y         AAG +P+    RE ++    E   Q+       P
Sbjct: 186 DAFELCKKAVEEY-GWY-------SRAAGYNPF---TREGKKTCSFEICEQL---NWEAP 231

Query: 225 DAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKA 284
           D V+  VG G+   GM+  F++   +G++   P    ++  E    +K       F  K 
Sbjct: 232 DKVLVAVGDGTILSGMWKGFVDFQKLGILEKMPQMIAVQ-AEGSDAIKRA-----FENKG 285

Query: 285 PMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEG 344
            +   +   I +S  ++   D  +     A   S G A  V++TD+E L A         
Sbjct: 286 EVTAVKAHTIADSILVNYPRD--AQLAVQALQESDGYA--VTVTDEEILAAIPEFARKAN 341

Query: 345 IIPALESSHALAHALKMMRENPDKEQ--LLVVNLSGRGDKDIFT 386
           I  A  +  A+  ALK + E    EQ   + + + G G KD ++
Sbjct: 342 IF-AEPAGAAVYAALKKLAEEGKIEQDETVAIVIGGNGLKDTYS 384


>UniRef50_UPI000180C4E2 PREDICTED: similar to Serine racemase n=1 Tax=Ciona intestinalis
           RepID=UPI000180C4E2
          Length = 321

 Score = 41.2 bits (95), Expect = 0.065,   Method: Compositional matrix adjust.
 Identities = 34/139 (24%), Positives = 54/139 (38%), Gaps = 7/139 (5%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T L  C++I       +++K E+    G+ K        L A      + +    +G HG
Sbjct: 27  TPLISCRSINDACGRKIFMKAENFQKSGSFKVRGAFNAVLSALEKDGVKSLVTHSSGNHG 86

Query: 117 VASALASALLGLKCRIYM--GAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEAL 174
           VA A    +L +   + M   A   +R+S   F     GAEVI      A  +  C E  
Sbjct: 87  VALAKVGRVLNIPVTVVMPKTAPPFKRKSATSF-----GAEVIECEPTHAERERKCEEVQ 141

Query: 175 RDWSGSYETAHYMLGTAAG 193
           R+    + ++   L   AG
Sbjct: 142 RNTEAMFVSSSQDLRVIAG 160


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_A6VPD9 Tryptophan synthase beta chain n=265 Tax=cellula...   625   e-177
UniRef50_B0TP63 Tryptophan synthase beta chain n=124 Tax=cellula...   599   e-170
UniRef50_P25269 Tryptophan synthase beta chain 2, chloroplastic ...   591   e-167
UniRef50_D2LTS0 Tryptophan synthase, beta subunit n=1 Tax=Bacill...   586   e-166
UniRef50_P00931 Tryptophan synthase n=45 Tax=Eukaryota RepID=TRP...   584   e-165
UniRef50_A1KSW2 Tryptophan synthase beta chain n=49 Tax=Bacteria...   583   e-165
UniRef50_B7FQI2 Predicted protein n=1 Tax=Phaeodactylum tricornu...   579   e-164
UniRef50_B1XY48 Tryptophan synthase beta chain n=287 Tax=cellula...   577   e-163
UniRef50_Q7VR00 Tryptophan synthase beta chain n=5 Tax=Bacteria ...   572   e-162
UniRef50_C9KJ78 Tryptophan synthase, beta subunit n=1 Tax=Mitsuo...   568   e-160
UniRef50_C5V964 Tryptophan synthase, beta subunit n=2 Tax=Coryne...   558   e-157
UniRef50_A5UMB9 Tryptophan synthase, beta subunit, TrpB n=5 Tax=...   557   e-157
UniRef50_A8Z5Y3 Putative tryptophan synthase, beta subunit (TrpB...   548   e-154
UniRef50_D0JB95 Bifunctional phosphoribosylanthranilate isomeras...   547   e-154
UniRef50_D1HPU5 Whole genome shotgun sequence of line PN40024, s...   541   e-152
UniRef50_Q2S700 Tryptophan synthase, beta subunit n=6 Tax=Bacter...   536   e-151
UniRef50_Q7VGA7 Tryptophan synthase beta chain n=4 Tax=Proteobac...   528   e-148
UniRef50_C0NSJ2 Bifunctional tryptophan synthase TRPB n=1 Tax=Aj...   522   e-147
UniRef50_D2VKV7 Predicted protein n=1 Tax=Naegleria gruberi RepI...   522   e-147
UniRef50_B2TM49 Tryptophan synthase beta chain n=40 Tax=cellular...   519   e-145
UniRef50_B2KCI5 Tryptophan synthase beta chain n=2 Tax=Bacteria ...   518   e-145
UniRef50_C1FGK1 Predicted protein n=14 Tax=cellular organisms Re...   516   e-145
UniRef50_Q822W9 Tryptophan synthase beta chain 1 n=8 Tax=Bacteri...   512   e-144
UniRef50_B0R332 Tryptophan synthase beta chain n=8 Tax=cellular ...   503   e-141
UniRef50_B0ZSJ6 Tryptophan synthase beta subunit n=3 Tax=rosids ...   503   e-141
UniRef50_Q0RGR3 Tryptophan synthase, beta protein n=2 Tax=Actino...   496   e-139
UniRef50_B7G4U3 Tryptophan synthase, beta chain n=3 Tax=cellular...   479   e-133
UniRef50_B8MZR1 Trytophan synthase alpha subunit, putative n=2 T...   479   e-133
UniRef50_C0QZH7 Tryptophan synthase beta subunit n=4 Tax=Bacteri...   471   e-131
UniRef50_Q1V1Q0 Tryptophan synthase beta chain 1 n=6 Tax=root Re...   450   e-125
UniRef50_A1DP73 Tryptophan synthase n=4 Tax=Trichocomaceae RepID...   436   e-121
UniRef50_B6HPP8 Pc22g00910 protein n=1 Tax=Penicillium chrysogen...   431   e-119
UniRef50_C8VGH6 Putative uncharacterized protein n=2 Tax=Emerice...   414   e-114
UniRef50_Q9WZ09 Tryptophan synthase beta chain 2 n=6 Tax=Bacteri...   382   e-105
UniRef50_D2L2T8 Pyridoxal-phosphate dependent TrpB-like enzyme n...   377   e-103
UniRef50_B6YSU5 Tryptophan synthase beta chain n=232 Tax=cellula...   376   e-102
UniRef50_A8F8F7 Tryptophan synthase beta chain n=12 Tax=cellular...   365   1e-99
UniRef50_Q13AA2 Tryptophan synthase, beta chain-like n=7 Tax=Bac...   356   6e-97
UniRef50_C7GZ56 Tryptophan synthase beta chain 2 n=3 Tax=Bacteri...   343   7e-93
UniRef50_C7N0P7 Pyridoxal-phosphate dependent TrpB-like enzyme n...   341   2e-92
UniRef50_Q9Y8T5 Tryptophan synthase beta chain 1 n=10 Tax=Thermo...   340   5e-92
UniRef50_Q970N1 Tryptophan synthase beta chain 2 n=16 Tax=Archae...   339   1e-91
UniRef50_C7DG26 Pyridoxal-phosphate dependent TrpB-like enzyme n...   337   4e-91
UniRef50_B1KQQ7 Pyridoxal-5'-phosphate-dependent protein beta su...   334   4e-90
UniRef50_A8M857 Pyridoxal-5'-phosphate-dependent protein beta su...   304   4e-81
UniRef50_D1NGU1 DNA (Cytosine-5-)-methyltransferase (Fragment) n...   285   2e-75
UniRef50_Q56YC7 Tryptophan synthase beta chain 1 n=3 Tax=cellula...   205   2e-51
UniRef50_D1C1V4 Threonine synthase n=3 Tax=Bacteria RepID=D1C1V4...   162   3e-38
UniRef50_C6TEW3 Putative uncharacterized protein (Fragment) n=1 ...   159   2e-37
UniRef50_A8HUC1 Tryptophan synthase beta subunit (Fragment) n=1 ...   134   6e-30
UniRef50_C1SGJ4 Tryptophan synthase beta chain n=1 Tax=Denitrovi...   133   1e-29
UniRef50_B9SZR5 Tryptophan synthase beta chain, putative n=1 Tax...   125   3e-27
UniRef50_O05626 Tryptophan synthase beta subunit (Fragment) n=1 ...   112   2e-23
UniRef50_Q44051 Transposon Mu dl-R insertion site. (Fragment) n=...    71   9e-11

Sequences not found previously or not previously below threshold:

UniRef50_B9L1Z4 Threonine synthase n=1 Tax=Thermomicrobium roseu...   116   2e-24
UniRef50_Q58860 Probable threonine synthase n=38 Tax=Archaea Rep...   115   3e-24
UniRef50_A5EK00 L-threonine synthase n=11 Tax=Bacteria RepID=A5E...   110   9e-23
UniRef50_C5CDJ9 Pyridoxal-5'-phosphate-dependent protein beta su...   109   2e-22
UniRef50_Q0W7Y3 Threonine synthase n=2 Tax=Euryarchaeota RepID=Q...   106   1e-21
UniRef50_C1E0J2 Predicted protein n=1 Tax=Micromonas sp. RCC299 ...   105   2e-21
UniRef50_A3DKY8 Transcriptional regulator n=1 Tax=Staphylothermu...   102   2e-20
UniRef50_B6YXA7 Hypothetical threonine synthase (TS) n=1 Tax=The...    99   3e-19
UniRef50_Q1IJB6 L-threonine synthase n=2 Tax=Bacteria RepID=Q1IJ...    98   5e-19
UniRef50_UPI00016C3ADC threonine synthase n=1 Tax=Gemmata obscur...    98   7e-19
UniRef50_C9RSS0 Threonine synthase n=13 Tax=Bacteria RepID=C9RSS...    98   7e-19
UniRef50_A0LFH6 Cysteine synthases n=15 Tax=cellular organisms R...    97   1e-18
UniRef50_C6A3C7 Threonine synthase n=6 Tax=cellular organisms Re...    96   3e-18
UniRef50_B5E900 Cysteine synthase n=1 Tax=Geobacter bemidjiensis...    93   2e-17
UniRef50_B2KE33 Threonine synthase n=1 Tax=Elusimicrobium minutu...    93   2e-17
UniRef50_B0VGY7 Putative threonine synthase n=1 Tax=Candidatus C...    93   2e-17
UniRef50_B4AUD2 Threonine synthase, putative n=23 Tax=Francisell...    92   3e-17
UniRef50_A2ETD5 Threonine synthase family protein n=1 Tax=Tricho...    92   4e-17
UniRef50_D2S0A7 Threonine synthase n=6 Tax=Halobacteriaceae RepI...    91   7e-17
UniRef50_Q8U4P9 Threonine synthase n=1 Tax=Pyrococcus furiosus R...    91   8e-17
UniRef50_B6A2K1 Pyridoxal-5'-phosphate-dependent protein beta su...    90   1e-16
UniRef50_D1B950 Pyridoxal-5'-phosphate-dependent protein beta su...    90   2e-16
UniRef50_A3DKP7 L-threonine synthase n=2 Tax=Desulfurococcaceae ...    90   2e-16
UniRef50_B0TBV3 Threonine synthase n=1 Tax=Heliobacterium modest...    89   2e-16
UniRef50_B3T1L2 Putative Pyridoxal-phosphate dependent enzyme n=...    89   3e-16
UniRef50_Q5WD43 Threonine synthase n=4 Tax=Bacillus RepID=Q5WD43...    89   3e-16
UniRef50_A9B1I1 Response regulator receiver protein n=1 Tax=Herp...    89   3e-16
UniRef50_C5CHS7 Threonine synthase n=2 Tax=Thermotogaceae RepID=...    88   4e-16
UniRef50_Q9K7E3 Threonine synthase n=82 Tax=cellular organisms R...    88   4e-16
UniRef50_C1TP96 Threonine synthase n=1 Tax=Dethiosulfovibrio pep...    88   5e-16
UniRef50_C6A3D2 Threonine synthase n=2 Tax=Thermococcus RepID=C6...    88   5e-16
UniRef50_A8MAW5 Threonine synthase n=1 Tax=Caldivirga maquilinge...    88   6e-16
UniRef50_A5V1I5 L-threonine ammonia-lyase n=2 Tax=Roseiflexus Re...    88   7e-16
UniRef50_B9JX06 Threonine dehydratase n=16 Tax=Alphaproteobacter...    87   9e-16
UniRef50_C1PE10 Threonine dehydratase n=2 Tax=Bacillaceae RepID=...    87   9e-16
UniRef50_D1BQL6 Cysteine synthase n=9 Tax=Firmicutes RepID=D1BQL...    87   1e-15
UniRef50_D1Y7Y8 Threonine synthase n=1 Tax=Pyramidobacter piscol...    87   1e-15
UniRef50_C4RAY2 Threonine synthase n=1 Tax=Micromonospora sp. AT...    87   1e-15
UniRef50_Q1QC42 Pyridoxal-5'-phosphate-dependent enzyme, beta su...    87   1e-15
UniRef50_A1S0F3 Threonine synthase-related protein n=1 Tax=Therm...    87   2e-15
UniRef50_D1CDZ3 Pyridoxal-5'-phosphate-dependent protein beta su...    87   2e-15
UniRef50_Q2SSZ6 Threonine dehydratase n=3 Tax=Mycoplasma mycoide...    86   2e-15
UniRef50_C6A508 Probable threonine synthase n=1 Tax=Thermococcus...    86   2e-15
UniRef50_C9M5D2 Threonine synthase n=1 Tax=Jonquetella anthropi ...    86   2e-15
UniRef50_A9BIT3 Threonine synthase n=4 Tax=Bacteria RepID=A9BIT3...    86   2e-15
UniRef50_C8W164 Cysteine synthase n=3 Tax=cellular organisms Rep...    86   3e-15
UniRef50_C6A2V6 Threonine dehydratase n=1 Tax=Thermococcus sibir...    85   5e-15
UniRef50_A7I331 Threonine dehydratase n=54 Tax=Bacteria RepID=A7...    84   1e-14
UniRef50_B5FEL5 Threonine synthase n=2 Tax=Vibrio fischeri RepID...    84   1e-14
UniRef50_A7IFG1 Pyridoxal-5'-phosphate-dependent protein beta su...    83   2e-14
UniRef50_Q04513 Threonine dehydratase biosynthetic n=34 Tax=Acti...    83   2e-14
UniRef50_Q4LEC5 Threonine synthase n=1 Tax=uncultured crenarchae...    83   2e-14
UniRef50_B9Z0N9 Pyridoxal-5'-phosphate-dependent protein beta su...    83   2e-14
UniRef50_Q1I705 Threonine synthase n=2 Tax=Pseudomonas RepID=Q1I...    83   2e-14
UniRef50_D0LAQ5 Threonine dehydratase n=6 Tax=Actinomycetales Re...    82   3e-14
UniRef50_B8J2I1 Cysteine synthase n=1 Tax=Desulfovibrio desulfur...    82   3e-14
UniRef50_Q6C6D8 YALI0E10307p n=1 Tax=Yarrowia lipolytica RepID=Q...    82   3e-14
UniRef50_A3DLF6 Cysteine synthase n=2 Tax=Desulfurococcaceae Rep...    82   4e-14
UniRef50_C6HUM2 Cysteine synthase n=1 Tax=Leptospirillum ferrodi...    82   4e-14
UniRef50_C7MM05 Cysteine synthase n=1 Tax=Cryptobacterium curtum...    82   5e-14
UniRef50_B9J9P9 Threonine dehydratase protein n=49 Tax=Alphaprot...    82   5e-14
UniRef50_Q3M387 L-threonine synthase n=107 Tax=cellular organism...    82   5e-14
UniRef50_C9KLW2 Threonine synthase n=2 Tax=Veillonellaceae RepID...    82   5e-14
UniRef50_A5CWZ8 Threonine dehydratase n=1 Tax=Candidatus Vesicom...    81   7e-14
UniRef50_P74193 Threonine synthase n=364 Tax=cellular organisms ...    81   7e-14
UniRef50_B8P126 Predicted protein n=6 Tax=cellular organisms Rep...    81   8e-14
UniRef50_B7G9B5 L-threonine ammonia-lyase n=3 Tax=cellular organ...    81   9e-14
UniRef50_D0N3C1 Cysteine synthase, putative n=1 Tax=Phytophthora...    80   1e-13
UniRef50_Q2RWP4 L-threonine ammonia-lyase n=1 Tax=Rhodospirillum...    80   2e-13
UniRef50_A4RXR0 Predicted protein n=16 Tax=cellular organisms Re...    80   2e-13
UniRef50_B6JWQ1 Threonine dehydratase n=1 Tax=Schizosaccharomyce...    80   2e-13
UniRef50_Q64CL8 Threonine synthase n=1 Tax=uncultured archaeon G...    80   2e-13
UniRef50_P55708 Putative cysteine synthase n=14 Tax=Proteobacter...    79   2e-13
UniRef50_B9LPA5 Pyridoxal-5'-phosphate-dependent protein beta su...    79   3e-13
UniRef50_D1C5Q2 Cystathionine beta-synthase n=30 Tax=Bacteria Re...    79   3e-13
UniRef50_B9KBA9 Tryptophan synthase beta chain 2 n=1 Tax=Thermot...    78   4e-13
UniRef50_B3TC24 Putative Pyridoxal-phosphate dependent enzyme n=...    78   4e-13
UniRef50_A3ERN7 Cysteine synthase n=2 Tax=Leptospirillum sp. Gro...    78   4e-13
UniRef50_C2BGX3 Threonine ammonia-lyase n=3 Tax=Anaerococcus Rep...    78   5e-13
UniRef50_A9ED40 Pyridoxal-phosphate dependent enzyme (Fragment) ...    78   6e-13
UniRef50_A6GXZ8 Cysteine synthase/cystathionine beta-synthase fa...    78   6e-13
UniRef50_P29848 Cysteine synthase B n=436 Tax=cellular organisms...    78   6e-13
UniRef50_A6F8H1 Threonine dehydratase n=1 Tax=Moritella sp. PE36...    77   9e-13
UniRef50_A2BKW1 Threonine synthase n=1 Tax=Hyperthermus butylicu...    77   9e-13
UniRef50_A1WTA6 L-threonine synthase n=12 Tax=Bacteria RepID=A1W...    77   1e-12
UniRef50_Q3M5I1 Cystathionine beta-synthase n=5 Tax=cellular org...    77   1e-12
UniRef50_A3ZYZ6 Threonine synthase n=2 Tax=Planctomycetaceae Rep...    77   1e-12
UniRef50_Q3A093 L-threonine ammonia-lyase n=9 Tax=Desulfuromonad...    77   1e-12
UniRef50_B2JXT2 Pyridoxal-5'-phosphate-dependent protein beta su...    77   1e-12
UniRef50_Q01PK6 Pyridoxal-5'-phosphate-dependent enzyme, beta su...    77   1e-12
UniRef50_D1AJT1 Threonine dehydratase n=8 Tax=Bacteria RepID=D1A...    76   1e-12
UniRef50_C1ZHQ7 Threonine dehydratase n=4 Tax=Bacteria RepID=C1Z...    76   2e-12
UniRef50_C5A936 Cysteine synthase n=1 Tax=Burkholderia glumae BG...    76   2e-12
UniRef50_B2A8I6 Cysteine synthase n=4 Tax=Clostridia RepID=B2A8I...    76   2e-12
UniRef50_C6A468 Cysteine synthase n=1 Tax=Thermococcus sibiricus...    76   2e-12
UniRef50_UPI0001978075 cysteine synthase n=1 Tax=Helicobacter ci...    76   2e-12
UniRef50_B0AA90 Cysteine synthase n=4 Tax=Firmicutes RepID=B0AA9...    76   2e-12
UniRef50_Q9Y9K2 Threonine synthase n=1 Tax=Aeropyrum pernix RepI...    76   3e-12
UniRef50_A6C9B2 Pyridoxal-5'-phosphate-dependent enzyme, beta su...    76   3e-12
UniRef50_Q2IRQ4 L-threonine synthase n=1 Tax=Rhodopseudomonas pa...    75   4e-12
UniRef50_Q97CB2 Threonine deaminase n=4 Tax=Thermoplasmatales Re...    75   4e-12
UniRef50_D2S288 Threonine dehydratase n=2 Tax=Haloterrigena turk...    75   4e-12
UniRef50_Q5WLV3 Cysteine synthase n=48 Tax=Bacteria RepID=Q5WLV3...    75   4e-12
UniRef50_Q93968 Protein T01H8.2, confirmed by transcript evidenc...    75   4e-12
UniRef50_D0L0K6 Threonine synthase n=20 Tax=Gammaproteobacteria ...    75   4e-12
UniRef50_B5YF95 Threonine dehydratase n=2 Tax=Dictyoglomus RepID...    75   4e-12
UniRef50_Q2PGG3 Serine racemase n=18 Tax=cellular organisms RepI...    75   4e-12
UniRef50_B3EGT7 Cysteine synthase A n=8 Tax=Bacteria RepID=B3EGT...    75   4e-12
UniRef50_D1CAF5 Pyridoxal-5'-phosphate-dependent protein beta su...    75   5e-12
UniRef50_C4LUI9 Threonine dehydratase, putative n=4 Tax=Entamoeb...    75   5e-12
UniRef50_C4Z926 Threonine dehydratase n=58 Tax=Bacteria RepID=C4...    75   7e-12
UniRef50_C6C043 Cysteine synthase n=5 Tax=Bacteria RepID=C6C043_...    74   8e-12
UniRef50_Q5HMF5 Threonine dehydratase biosynthetic n=12 Tax=Bact...    74   8e-12
UniRef50_A9M562 Threonine dehydratase n=47 Tax=Alphaproteobacter...    74   9e-12
UniRef50_UPI0001903713 tryptophan synthase subunit beta n=1 Tax=...    74   9e-12
UniRef50_Q88I11 Threonine dehydratase family protein n=43 Tax=ce...    74   9e-12
UniRef50_Q1AYU1 Cysteine synthase n=5 Tax=Bacteria RepID=Q1AYU1_...    74   1e-11
UniRef50_C9NEG9 Cysteine synthase n=1 Tax=Streptomyces flavogris...    74   1e-11
UniRef50_B9L1A5 Threonine ammonia-lyase, biosynthetic n=2 Tax=Th...    74   1e-11
UniRef50_C4V2P7 Threonine ammonia-lyase n=1 Tax=Selenomonas flue...    73   1e-11
UniRef50_Q3ISH9 Threonine synthase 3 n=1 Tax=Natronomonas pharao...    73   1e-11
UniRef50_P17324 L-serine dehydratase n=12 Tax=Fungi/Metazoa grou...    73   1e-11
UniRef50_A0RIY6 Cysteine synthase n=101 Tax=Bacteria RepID=A0RIY...    73   1e-11
UniRef50_A8ZXL4 Cysteine synthase n=15 Tax=cellular organisms Re...    73   1e-11
UniRef50_D1B631 Threonine synthase n=2 Tax=Bacteria RepID=D1B631...    73   1e-11
UniRef50_A8ABB1 L-threonine synthase n=45 Tax=cellular organisms...    73   1e-11
UniRef50_C7N157 Cysteine synthase n=3 Tax=Bacteria RepID=C7N157_...    73   2e-11
UniRef50_A8MDC1 Threonine dehydratase n=9 Tax=cellular organisms...    73   2e-11
UniRef50_Q2SDR6 Threonine dehydratase n=1 Tax=Hahella chejuensis...    73   2e-11
UniRef50_Q28WC6 L-threonine ammonia-lyase n=35 Tax=Alphaproteoba...    73   2e-11
UniRef50_C4XII8 Cysteine synthase B n=3 Tax=Desulfovibrio RepID=...    73   2e-11
UniRef50_D1IAP7 Whole genome shotgun sequence of line PN40024, s...    73   2e-11
UniRef50_C5EHA5 L-threonine synthase n=1 Tax=Clostridiales bacte...    73   2e-11
UniRef50_Q54HH2 Probable serine racemase n=1 Tax=Dictyostelium d...    72   3e-11
UniRef50_A0E1N6 Cysteine synthase n=2 Tax=Oligohymenophorea RepI...    72   3e-11
UniRef50_A5IQ12 Cysteine synthase n=51 Tax=Staphylococcus aureus...    72   3e-11
UniRef50_Q2CF35 Threonine synthase n=1 Tax=Oceanicola granulosus...    72   3e-11
UniRef50_Q17VY7 Cysteine synthase n=29 Tax=Bacteria RepID=Q17VY7...    72   3e-11
UniRef50_A7INC1 Threonine dehydratase n=6 Tax=Alphaproteobacteri...    72   4e-11
UniRef50_Q07RL7 L-threonine ammonia-lyase n=40 Tax=Bacteria RepI...    72   4e-11
UniRef50_A0LG82 L-threonine ammonia-lyase n=2 Tax=cellular organ...    72   4e-11
UniRef50_C1AEM2 Cystathionine beta-synthase n=1 Tax=Gemmatimonas...    72   4e-11
UniRef50_Q9X7F1 Probable threonine dehydratase biosynthetic n=24...    72   4e-11
UniRef50_A4FDD4 1-aminocyclopropane-1-carboxylate deaminase n=15...    72   4e-11
UniRef50_B6YXV5 Threonine synthase n=2 Tax=Thermococcus RepID=B6...    71   5e-11
UniRef50_C3J6F5 Cysteine synthase n=2 Tax=Bacillaceae RepID=C3J6...    71   5e-11
UniRef50_C6UN42 Putative cysteine synthase A n=1 Tax=Candidatus ...    71   5e-11
UniRef50_B0R722 Threonine ammonia-lyase n=12 Tax=cellular organi...    71   6e-11
UniRef50_D2B021 Pyridoxal-5'-phosphate-dependent protein beta su...    71   6e-11
UniRef50_Q10725 Phenylserine dehydratase n=62 Tax=Proteobacteria...    71   6e-11
UniRef50_B1KBC9 Cysteine synthase n=7 Tax=Bacteria RepID=B1KBC9_...    71   6e-11
UniRef50_O34476 Probable cysteine synthase n=7 Tax=Bacteria RepI...    71   7e-11
UniRef50_UPI000180BB5B PREDICTED: similar to Serine racemase n=2...    71   7e-11
UniRef50_C5DI11 Cysteine synthase n=19 Tax=Saccharomyceta RepID=...    71   7e-11
UniRef50_B0T581 Cysteine synthase n=51 Tax=Bacteria RepID=B0T581...    71   7e-11
UniRef50_D1TEY8 Pyridoxal-5'-phosphate-dependent protein beta su...    71   8e-11
UniRef50_Q2RHT1 Cysteine synthase n=6 Tax=Bacteria RepID=Q2RHT1_...    71   8e-11
UniRef50_Q8YXP3 Cysteine synthase n=2 Tax=Nostoc sp. PCC 7120 Re...    71   9e-11
UniRef50_P71128 Cysteine synthase B n=12 Tax=Campylobacter RepID...    71   9e-11
UniRef50_P50867 Cysteine synthase n=103 Tax=cellular organisms R...    71   1e-10
UniRef50_A6WWN6 Threonine synthase n=3 Tax=Rhizobiales RepID=A6W...    70   1e-10
UniRef50_Q9R6V6 ANL49 n=1 Tax=Synechococcus elongatus PCC 7942 R...    70   1e-10
UniRef50_B9L6H6 Cysteine synthase n=2 Tax=Nautiliaceae RepID=B9L...    70   1e-10
UniRef50_Q2S090 Threonine dehydratase n=6 Tax=cellular organisms...    70   1e-10
UniRef50_UPI0001926B07 PREDICTED: similar to predicted protein n...    70   1e-10
UniRef50_C5FWS0 L-serine dehydratase n=3 Tax=Onygenales RepID=C5...    70   1e-10
UniRef50_B3TC39 Putative Pyridoxal-phosphate dependent enzyme n=...    70   1e-10
UniRef50_O94634 Threonine dehydratase, mitochondrial n=5 Tax=cel...    70   1e-10
UniRef50_UPI000180C083 PREDICTED: similar to serine dehydratase ...    70   1e-10
UniRef50_Q22B57 Threonine dehydratase family protein n=2 Tax=cel...    70   2e-10
UniRef50_B1ZNK1 Pyridoxal-5'-phosphate-dependent protein beta su...    70   2e-10
UniRef50_A1KYC1 Serine dehydratase n=1 Tax=Aplysia californica R...    70   2e-10
UniRef50_B2UPE5 Pyridoxal-5'-phosphate-dependent protein beta su...    70   2e-10
UniRef50_C9N4U4 Pyridoxal-5'-phosphate-dependent protein beta su...    69   2e-10
UniRef50_C5A2G0 Threonine synthase (ThrC) n=1 Tax=Thermococcus g...    69   2e-10
UniRef50_A6NZW4 Putative uncharacterized protein n=2 Tax=Bacteri...    69   2e-10
UniRef50_D1X751 Pyridoxal-5'-phosphate-dependent protein beta su...    69   3e-10
UniRef50_A6GJR2 Cysteine synthase n=1 Tax=Plesiocystis pacifica ...    69   3e-10
UniRef50_A8MDP7 Pyridoxal-5'-phosphate-dependent protein beta su...    69   3e-10
UniRef50_A7RTQ8 Predicted protein n=2 Tax=Nematostella vectensis...    69   3e-10
UniRef50_B2YI91 Threonine synthase n=1 Tax=uncultured crenarchae...    69   3e-10
UniRef50_C7BSG1 Cysteine synthase n=2 Tax=Gammaproteobacteria Re...    69   3e-10
UniRef50_Q7MYV0 Cysteine synthase n=1 Tax=Photorhabdus luminesce...    69   3e-10
UniRef50_A8MA47 Pyridoxal-5'-phosphate-dependent protein beta su...    69   3e-10
UniRef50_O59701 Cysteine synthase 1 n=133 Tax=cellular organisms...    69   3e-10
UniRef50_A9GRV5 Cysteine synthase n=3 Tax=cellular organisms Rep...    69   3e-10
UniRef50_Q3ADX2 Cysteine synthase n=10 Tax=cellular organisms Re...    69   3e-10
UniRef50_O05393 O-acetylserine dependent cystathionine beta-synt...    69   3e-10
UniRef50_UPI00006CA830 Pyridoxal-phosphate dependent enzyme fami...    69   4e-10
UniRef50_B1L3T1 Threonine synthase n=1 Tax=Candidatus Korarchaeu...    68   4e-10
UniRef50_C1ED55 Cysteine synthase n=24 Tax=cellular organisms Re...    68   4e-10
UniRef50_B6VLL1 Cysteine synthase n=1 Tax=Photorhabdus asymbioti...    68   4e-10
UniRef50_B9KDA6 Cysteine synthase n=2 Tax=Campylobacterales RepI...    68   4e-10
UniRef50_C3MRI3 Threonine dehydratase n=12 Tax=Sulfolobaceae Rep...    68   5e-10
UniRef50_C7LQS0 Cysteine synthase n=2 Tax=Desulfovibrionales Rep...    68   5e-10
UniRef50_C2HF35 Cysteine synthase n=1 Tax=Finegoldia magna ATCC ...    68   5e-10

>UniRef50_A6VPD9 Tryptophan synthase beta chain n=265 Tax=cellular organisms
           RepID=TRPB_ACTSZ
          Length = 398

 Score =  625 bits (1611), Expect = e-177,   Method: Composition-based stats.
 Identities = 321/395 (81%), Positives = 355/395 (89%)

Query: 3   TLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKC 62
           T+LNPYFGEFGGMYVP+IL+P L+QLE+AFV A+ DP+FQ +F DLLKNYAGRPTALT C
Sbjct: 4   TILNPYFGEFGGMYVPEILVPVLQQLEKAFVEARNDPDFQQEFQDLLKNYAGRPTALTLC 63

Query: 63  QNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALA 122
           +N+T GT T LYLKREDLLHGGAHKTNQVLGQ LLAKRMGKT IIAETGAGQHGVA+ALA
Sbjct: 64  RNLTKGTKTKLYLKREDLLHGGAHKTNQVLGQILLAKRMGKTRIIAETGAGQHGVATALA 123

Query: 123 SALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYE 182
            A+L + CR+YMG+KDVERQSPNVFRMRLMG EV+PV  GS +LKDAC EA+RDWS +YE
Sbjct: 124 CAMLDMPCRVYMGSKDVERQSPNVFRMRLMGTEVVPVEKGSCSLKDACCEAMRDWSANYE 183

Query: 183 TAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFA 242
             HY+LGTAAGPHP+PTIVREFQ+MIGEETK QILE+EG LPDAVIA VGGGSNAIGMF 
Sbjct: 184 NTHYLLGTAAGPHPFPTIVREFQKMIGEETKRQILEKEGCLPDAVIAAVGGGSNAIGMFT 243

Query: 243 DFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISA 302
           DFI+ETNV LIGVEP G GIETGEHGAPLKHG+ GIYFGMK+P+MQTEDGQIEESYSISA
Sbjct: 244 DFIDETNVRLIGVEPAGKGIETGEHGAPLKHGKTGIYFGMKSPIMQTEDGQIEESYSISA 303

Query: 303 GLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMM 362
           GLDFPSVGPQHAYLNS GRA+Y SITDDEAL AFK L  HEGIIPALESSHALA ALKM+
Sbjct: 304 GLDFPSVGPQHAYLNSIGRAEYPSITDDEALAAFKELAKHEGIIPALESSHALAQALKMI 363

Query: 363 RENPDKEQLLVVNLSGRGDKDIFTVHDILKARGEI 397
           + NP+KEQLLVVNLSGRGDKDIFTV  IL+A+GE+
Sbjct: 364 KSNPEKEQLLVVNLSGRGDKDIFTVDKILRAKGEL 398


>UniRef50_B0TP63 Tryptophan synthase beta chain n=124 Tax=cellular organisms
           RepID=TRPB_SHEHH
          Length = 419

 Score =  599 bits (1544), Expect = e-170,   Method: Composition-based stats.
 Identities = 307/392 (78%), Positives = 342/392 (87%), Gaps = 1/392 (0%)

Query: 3   TLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKC 62
           + LNPYFGE+GGMYVPQILMPAL+QLE AF+ AQ+D  FQ +F DLLKNYAGRPTALT  
Sbjct: 2   SKLNPYFGEYGGMYVPQILMPALKQLETAFIEAQEDEAFQEEFTDLLKNYAGRPTALTLT 61

Query: 63  QNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALA 122
           +N++      +YLKREDLLHGGAHKTNQVLGQALLAKRMGK EIIAETGAGQHGVA+ALA
Sbjct: 62  RNLSPNPLAKIYLKREDLLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVATALA 121

Query: 123 SALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYE 182
            ALLGLKCR+YMGAKDVERQSPNVFRM+LMGAEVIPV SGSATLKDACNEA+RDWSG Y+
Sbjct: 122 CALLGLKCRVYMGAKDVERQSPNVFRMKLMGAEVIPVTSGSATLKDACNEAMRDWSGCYD 181

Query: 183 TAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFA 242
            AHY+LGTAAGPHPYPTIVREFQRMIG ETK QILEREGRLPDAVIACVGGGSNAIGMFA
Sbjct: 182 KAHYLLGTAAGPHPYPTIVREFQRMIGAETKRQILEREGRLPDAVIACVGGGSNAIGMFA 241

Query: 243 DFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISA 302
           DFI+E  V LIGVEP G GI+T  HGAPL HG+ GI+FGMKAP+MQ  +GQ+EESYS+SA
Sbjct: 242 DFIDEPEVALIGVEPAGKGIDTPMHGAPLHHGKTGIFFGMKAPLMQDSEGQVEESYSVSA 301

Query: 303 GLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMM 362
           GLDFPSVGPQHA+L + GRA Y S TDDEALE F+ L   EGIIPALES+HA+A+A+K+ 
Sbjct: 302 GLDFPSVGPQHAHLAAIGRATYESATDDEALETFQLLARCEGIIPALESAHAIAYAVKLA 361

Query: 363 RENPDKEQLLVVNLSGRGDKDIFTVHDILKAR 394
           +E   KE LLVVNLSGRGDKDIFTV DIL+ +
Sbjct: 362 KEAT-KETLLVVNLSGRGDKDIFTVADILEQQ 392


>UniRef50_P25269 Tryptophan synthase beta chain 2, chloroplastic n=1628 Tax=cellular
           organisms RepID=TRBP2_ARATH
          Length = 475

 Score =  591 bits (1523), Expect = e-167,   Method: Composition-based stats.
 Identities = 215/392 (54%), Positives = 283/392 (72%), Gaps = 7/392 (1%)

Query: 7   PYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNIT 66
             FG+FGG YVP+ LM AL +LE AF S   D +FQ +  ++LK+Y GR + L   + +T
Sbjct: 84  GRFGKFGGKYVPETLMHALSELETAFYSLATDEDFQRELAEILKDYVGRESPLYFAERLT 143

Query: 67  AGT------NTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASA 120
                       +YLKREDL H GAHK N  + QALLAKR+GK  IIAETGAGQHGVA+A
Sbjct: 144 EHYRRENGEGPLIYLKREDLNHTGAHKINNAVAQALLAKRLGKKRIIAETGAGQHGVATA 203

Query: 121 LASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGS 180
              A  GL+C IYMGA+D+ERQ+ NVFRMRL+GAEV  VHSG+ATLKDA +EA+RDW  +
Sbjct: 204 TVCARFGLQCIIYMGAQDMERQALNVFRMRLLGAEVRGVHSGTATLKDATSEAIRDWVTN 263

Query: 181 YETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGM 240
            ET HY+LG+ AGPHPYP +VR+F  +IG+ET+ Q +E+ G  PD ++ACVGGGSNA+G+
Sbjct: 264 VETTHYILGSVAGPHPYPMMVRDFHAVIGKETRKQAMEKWGGKPDVLVACVGGGSNAMGL 323

Query: 241 FADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSI 300
           F +F+++T V +IGVE  G G+++G+H A L  G VG+  G  + ++Q +DGQI E +SI
Sbjct: 324 FHEFVDDTEVRMIGVEAAGFGLDSGKHAATLTKGDVGVLHGAMSYLLQDDDGQIIEPHSI 383

Query: 301 SAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALK 360
           SAGLD+P VGP+H++L   GRA+Y S+TD+EALEAFK +   EGIIPALE+SHALAH  K
Sbjct: 384 SAGLDYPGVGPEHSFLKDVGRAEYFSVTDEEALEAFKRVSRLEGIIPALETSHALAHLEK 443

Query: 361 MMRENPDKEQLLVVNLSGRGDKDIFTVHDILK 392
           +    PD  ++++ N SGRGDKD+ T    L+
Sbjct: 444 LCPTLPDGARVVL-NFSGRGDKDVQTAIKYLE 474


>UniRef50_D2LTS0 Tryptophan synthase, beta subunit n=1 Tax=Bacillus cellulosilyticus
           DSM 2522 RepID=D2LTS0_BACS4
          Length = 611

 Score =  586 bits (1510), Expect = e-166,   Method: Composition-based stats.
 Identities = 211/388 (54%), Positives = 270/388 (69%), Gaps = 2/388 (0%)

Query: 7   PYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNIT 66
             FG+FGG YVP+ LM AL QLE AF  A +D  F A+ ++  + Y+GRPT LT  + ++
Sbjct: 221 GRFGDFGGRYVPETLMYALEQLESAFDEAVQDEHFFAELHNEWEKYSGRPTPLTVAERLS 280

Query: 67  AGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASAL 125
                 ++YLKREDL H GAHK N  + QA+LAKRMGK +IIAETGAGQHGVA+A  +A 
Sbjct: 281 KTLGGASIYLKREDLNHTGAHKINNAIAQAILAKRMGKQQIIAETGAGQHGVAAATVAAR 340

Query: 126 LGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAH 185
            GL C+++MG +D++RQ  NVFRM+L+GAEVI V SG  TLKDA NEA+R W        
Sbjct: 341 FGLTCKVFMGEEDMKRQELNVFRMKLLGAEVIKVTSGGKTLKDATNEAIRHWVSHVNDTF 400

Query: 186 YMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFI 245
           Y++G+A GPHPYP +VREFQ +IG E++ Q L   G LPD VIACVGGGSNAIGMF  FI
Sbjct: 401 YLIGSAVGPHPYPKMVREFQSVIGRESRRQFLTETGALPDEVIACVGGGSNAIGMFYPFI 460

Query: 246 NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLD 305
           N+  V L GVE  G G++T EH A L  G  G+  G  + ++Q + G I E YSISAGLD
Sbjct: 461 NDEQVVLTGVEAAGKGVDTEEHAATLTKGVKGVLHGSLSYLLQDDFGNITEPYSISAGLD 520

Query: 306 FPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMREN 365
           +P +GP+HAYL   GR  Y SITD EA+EA +TLC  EGI+PA+ES+HALA A K  +E 
Sbjct: 521 YPGIGPEHAYLRDIGRVSYESITDKEAIEALQTLCQLEGILPAIESAHALAQAFKRAKEL 580

Query: 366 PDKEQLLVVNLSGRGDKDIFTVHDILKA 393
            + +  ++V LSGRGDKD+ T+  +L+ 
Sbjct: 581 SEGKT-ILVCLSGRGDKDVHTIQGVLEG 607


>UniRef50_P00931 Tryptophan synthase n=45 Tax=Eukaryota RepID=TRP_YEAST
          Length = 707

 Score =  584 bits (1507), Expect = e-165,   Method: Composition-based stats.
 Identities = 204/390 (52%), Positives = 276/390 (70%), Gaps = 4/390 (1%)

Query: 8   YFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITA 67
            FG+FGG YVP+ L   LR+LE+ F  A  DP F   F  L  +Y GRP++L K + +T 
Sbjct: 305 RFGDFGGQYVPEALHACLRELEKGFDEAVADPTFWEDFKSLY-SYIGRPSSLHKAERLTE 363

Query: 68  GT-NTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALL 126
                 ++LKREDL H G+HK N  L Q LLAKR+GK  +IAETGAGQHGVA+A A A  
Sbjct: 364 HCQGAQIWLKREDLNHTGSHKINNALAQVLLAKRLGKKNVIAETGAGQHGVATATACAKF 423

Query: 127 GLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHY 186
           GL C ++MGA+DV RQ+ NVFRMR++GA+VI V +G+ TL+DA +EA R W  + +T +Y
Sbjct: 424 GLTCTVFMGAEDVRRQALNVFRMRILGAKVIAVTNGTKTLRDATSEAFRFWVTNLKTTYY 483

Query: 187 MLGTAAGPHPYPTIVREFQRMIGEETKAQILER-EGRLPDAVIACVGGGSNAIGMFADFI 245
           ++G+A GPHPYPT+VR FQ +IG+ETK Q      G+LPDAV+ACVGGGSN+ GMF+ F 
Sbjct: 484 VVGSAIGPHPYPTLVRTFQSVIGKETKEQFAAMNNGKLPDAVVACVGGGSNSTGMFSPFE 543

Query: 246 NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLD 305
           ++T+V L+GVE GG G++T  H A L  GR G++ G+K  ++Q  DGQ+ +++S+SAGLD
Sbjct: 544 HDTSVKLLGVEAGGDGVDTKFHSATLTAGRPGVFHGVKTYVLQDSDGQVHDTHSVSAGLD 603

Query: 306 FPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMREN 365
           +P VGP+ AY  STGRA +++ TD +AL  FK L   EGIIPALESSHA+  A ++ +  
Sbjct: 604 YPGVGPELAYWKSTGRAQFIAATDAQALLGFKLLSQLEGIIPALESSHAVYGACELAKTM 663

Query: 366 PDKEQLLVVNLSGRGDKDIFTVHDILKARG 395
              +Q LV+N+SGRGDKD+ +V ++L   G
Sbjct: 664 KP-DQHLVINISGRGDKDVQSVAEVLPKLG 692


>UniRef50_A1KSW2 Tryptophan synthase beta chain n=49 Tax=Bacteria RepID=TRPB_NEIMF
          Length = 400

 Score =  583 bits (1502), Expect = e-165,   Method: Composition-based stats.
 Identities = 208/390 (53%), Positives = 277/390 (71%), Gaps = 3/390 (0%)

Query: 7   PYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNIT 66
            +FGE GG++V + L+PAL++L +A+ +A+ DPEF   F   LK+Y GRP+ +     ++
Sbjct: 11  GFFGEHGGLFVSETLIPALQELADAYKAAKNDPEFWEAFRHDLKHYVGRPSPVYHAARLS 70

Query: 67  AGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASAL 125
                  ++LKREDL H GAHK N  +GQALLAKRMGK  +IAETGAGQHGVASA  +A 
Sbjct: 71  EHLGGAQIWLKREDLNHTGAHKVNNTIGQALLAKRMGKKRVIAETGAGQHGVASATVAAR 130

Query: 126 LGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAH 185
            G+ C +YMGA D++RQ PNVFRM+L+GA V+ V SGS TLKDA NEA+R+W    +   
Sbjct: 131 FGMTCDVYMGADDIQRQMPNVFRMKLLGANVVGVESGSRTLKDAMNEAMREWVARVDDTF 190

Query: 186 YMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFI 245
           Y++GTAAGP PYP +VR+FQ +IG E KAQ+ E  GR PD  +ACVGGGSNAIG+F  +I
Sbjct: 191 YIIGTAAGPAPYPEMVRDFQCVIGNEAKAQMQEAIGRQPDVAVACVGGGSNAIGLFHPYI 250

Query: 246 NETNVGLIGVEPGGHGIETGEHGAPLKHGRV-GIYFGMKAPMMQTEDGQIEESYSISAGL 304
            E NV L+GVE GG G+ T +H AP+  G   G+  G ++ +MQ E+GQ+  ++S+SAGL
Sbjct: 251 GEENVRLVGVEAGGLGVNTPDHAAPITSGAPIGVLHGFRSYLMQDENGQVLGTHSVSAGL 310

Query: 305 DFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRE 364
           D+P +GP+H++L+   R +Y    DDEALEAF  LC  EGIIPALESSHA+A A+K   +
Sbjct: 311 DYPGIGPEHSHLHDIKRVEYTVAKDDEALEAFDLLCRFEGIIPALESSHAVAWAVKNAPK 370

Query: 365 NPDKEQLLVVNLSGRGDKDIFTVHDILKAR 394
              K+Q+++VNLSGRGDKDI TV  +   +
Sbjct: 371 M-GKDQVILVNLSGRGDKDINTVAKLKGIK 399


>UniRef50_B7FQI2 Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1
           RepID=B7FQI2_PHATR
          Length = 671

 Score =  579 bits (1492), Expect = e-164,   Method: Composition-based stats.
 Identities = 203/388 (52%), Positives = 273/388 (70%), Gaps = 3/388 (0%)

Query: 6   NPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNI 65
           N  FG+FGG Y+P+ L  A  ++E ++   + DP F A+ ++  +++ G PT L +   +
Sbjct: 281 NSRFGKFGGQYIPETLSVAFEEIEASYNELKDDPSFLAELDEYRRDFVGGPTPLHRADRL 340

Query: 66  TA-GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASA 124
           T      T++LKREDL H GAHK N  +GQALLAKR+GK  IIAETGAGQHGVA+A   A
Sbjct: 341 TELAGGATIWLKREDLAHTGAHKINNAIGQALLAKRIGKPRIIAETGAGQHGVATATICA 400

Query: 125 LLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETA 184
            LGL C +YMGA D ERQ  NVFRM  +GA+V+PV  G  TLKDA NEA+RDW  +    
Sbjct: 401 KLGLDCTVYMGAVDCERQKLNVFRMNTLGAKVVPVQDGQRTLKDAINEAMRDWVTNVRDT 460

Query: 185 HYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADF 244
           HY++G+A GPHP+PTIVR+FQ ++G E +AQ+LER G+LPDAV+ACVGGGSNAIG F  F
Sbjct: 461 HYLIGSAVGPHPFPTIVRDFQSVMGREMRAQMLERAGKLPDAVVACVGGGSNAIGAFHPF 520

Query: 245 INETNVGLIGVEPGGHGIET-GEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAG 303
           +N+  V L GVE  G+GI+   EH A L  G  G+  G    ++Q + GQ   ++SISAG
Sbjct: 521 VNDETVELHGVEAAGYGIDKDEEHCATLTKGTPGVLQGAMTYVIQQKSGQTLNTHSISAG 580

Query: 304 LDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMR 363
           LD+P VGP+HA+L  +GRA Y ++TDDEALE FK +C +EGIIPALE+SHA+ +A+K+ +
Sbjct: 581 LDYPGVGPEHAFLKDSGRAVYEAVTDDEALEGFKLMCEYEGIIPALETSHAIYYAVKLAK 640

Query: 364 ENPDKEQLLVVNLSGRGDKDIFTVHDIL 391
           +    +  +V+N+SGRGDKD+  +  I+
Sbjct: 641 KLGPGKD-IVINMSGRGDKDMPQIAKIM 667


>UniRef50_B1XY48 Tryptophan synthase beta chain n=287 Tax=cellular organisms
           RepID=TRPB_LEPCP
          Length = 428

 Score =  577 bits (1488), Expect = e-163,   Method: Composition-based stats.
 Identities = 210/385 (54%), Positives = 277/385 (71%), Gaps = 2/385 (0%)

Query: 7   PYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNIT 66
            +FG +GG +V + L  AL +L  A+   + DPEF A+F + L ++ GRP+ +     ++
Sbjct: 11  GHFGIYGGSFVAETLSHALDELNAAYERYRHDPEFIAEFRNELAHFVGRPSPVYHAARMS 70

Query: 67  AG-TNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASAL 125
                  +YLKREDL H GAHK N  +GQALLA+RMGK  +IAETGAGQHGVA+A   A 
Sbjct: 71  REVGGAQIYLKREDLNHTGAHKINNTIGQALLARRMGKPRVIAETGAGQHGVATATICAR 130

Query: 126 LGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAH 185
            G++C +YMG++DV+RQSPNV+RM L+GA V+PV SGS TLKDA NEA+RDW  + E   
Sbjct: 131 YGMECVVYMGSEDVKRQSPNVYRMNLLGARVVPVESGSKTLKDALNEAMRDWVTNVENTF 190

Query: 186 YMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFI 245
           Y++GT AGPHPYP +VR+FQR+IG+E   Q+    GR PDAV+ACVGGGSNA+G+F  +I
Sbjct: 191 YIIGTVAGPHPYPAMVRDFQRVIGDECLVQMPALAGRQPDAVVACVGGGSNAMGIFYPYI 250

Query: 246 NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLD 305
               V LIGVE  G G+E+G+H A L+ G  G+  G +  ++Q  +GQI E++S+SAGLD
Sbjct: 251 PHEGVRLIGVEAAGEGMESGKHSASLQRGSPGVLHGNRTYVLQDANGQITETHSVSAGLD 310

Query: 306 FPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMREN 365
           +P VGP+HAYL   GRA+YV ITD EAL+AF  LC  EGIIPALESSHA+A+A+K+ +  
Sbjct: 311 YPGVGPEHAYLKDIGRAEYVGITDAEALQAFHYLCRAEGIIPALESSHAVAYAMKLAKTM 370

Query: 366 PDKEQLLVVNLSGRGDKDIFTVHDI 390
              +Q ++VNLSGRGDKDI TV D+
Sbjct: 371 RP-DQHVLVNLSGRGDKDIGTVADL 394


>UniRef50_Q7VR00 Tryptophan synthase beta chain n=5 Tax=Bacteria RepID=TRPB_BLOFL
          Length = 398

 Score =  572 bits (1475), Expect = e-162,   Method: Composition-based stats.
 Identities = 268/391 (68%), Positives = 325/391 (83%)

Query: 1   MTTLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALT 60
           MT  L+ YFGEFGGMYVPQIL+PAL QLE+ F+ A KD  FQ  F +LL +YAGRPT LT
Sbjct: 1   MTQQLHSYFGEFGGMYVPQILIPALIQLEKEFIEAMKDISFQTTFKNLLHHYAGRPTPLT 60

Query: 61  KCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASA 120
            CQN+T+GT + LYLKREDLLHGG+HKTNQVLGQALLAKRM K EIIAETGAGQHGVA +
Sbjct: 61  LCQNLTSGTCSKLYLKREDLLHGGSHKTNQVLGQALLAKRMHKKEIIAETGAGQHGVAVS 120

Query: 121 LASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGS 180
           +AS+LL LKCRIYMG KD++RQ  NV RM+LMG +VIPVH GSATLKDACNEA+R+WS +
Sbjct: 121 IASSLLKLKCRIYMGYKDMKRQELNVLRMKLMGTQVIPVHHGSATLKDACNEAIREWSST 180

Query: 181 YETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGM 240
           Y+  HYM+GT AGPHP+PTIV+EFQR+IG ET  QI   E +LPDAVIAC+GGGSNAIG+
Sbjct: 181 YKHTHYMIGTVAGPHPFPTIVKEFQRIIGSETYNQIQTHEKKLPDAVIACIGGGSNAIGI 240

Query: 241 FADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSI 300
           F+ FI+  +V L+GVE GG G+ T  HG+ L+ G  GIYFGMK+P++Q+++GQI+ SYSI
Sbjct: 241 FSGFIDIPSVQLLGVEAGGLGLHTEYHGSSLQCGETGIYFGMKSPILQSQEGQIKNSYSI 300

Query: 301 SAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALK 360
           +AGLDFPSVGP+HAYL    R  YVSI D+EA+ AF+ L L+EGIIPALES+HALAHALK
Sbjct: 301 AAGLDFPSVGPEHAYLKKINRVKYVSINDEEAINAFQELSLYEGIIPALESAHALAHALK 360

Query: 361 MMRENPDKEQLLVVNLSGRGDKDIFTVHDIL 391
           ++R+ P K+Q+L+VNLSGRGDKDI TV++ L
Sbjct: 361 IIRKTPKKKQILIVNLSGRGDKDIITVNNAL 391


>UniRef50_C9KJ78 Tryptophan synthase, beta subunit n=1 Tax=Mitsuokella multacida DSM
           20544 RepID=C9KJ78_9FIRM
          Length = 395

 Score =  568 bits (1463), Expect = e-160,   Method: Composition-based stats.
 Identities = 216/392 (55%), Positives = 276/392 (70%), Gaps = 3/392 (0%)

Query: 7   PYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNIT 66
             FG+FGG YVP+I+MPAL +LE A+   + DP+FQ +F   L+ YAGRPT L     +T
Sbjct: 5   GRFGKFGGQYVPEIVMPALNELEAAYAKYKDDPDFQNEFKTYLREYAGRPTNLYYADKLT 64

Query: 67  AGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASAL 125
                  ++LKREDLLH GAHK N  LGQALLAKRMGK  I+AETGAGQHGVASA  +AL
Sbjct: 65  KYYGRAKIFLKREDLLHTGAHKINNALGQALLAKRMGKKRIVAETGAGQHGVASATVAAL 124

Query: 126 LGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAH 185
            G++C ++MGA DVERQ  NVFRM+L+GA+VIPV SG+ TLKDA +EA+R W+ +    H
Sbjct: 125 FGMECHVFMGALDVERQKLNVFRMKLLGAKVIPVSSGTGTLKDATSEAIRYWATNITDTH 184

Query: 186 YMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFI 245
           Y++G+A GPHPYPTIVR+FQ++IGEE + Q +E+ G LPD ++ACVGGGSNAIG F DF 
Sbjct: 185 YIIGSAVGPHPYPTIVRDFQKVIGEEIREQAIEKIGGLPDYLLACVGGGSNAIGTFYDFR 244

Query: 246 NETNVGLIGVEPGGHGIETGEHGAPLK-HGRVGIYFGMKAPMMQTEDGQIEESYSISAGL 304
           N+ +V   GVE GG G    ++   L   G  GI  G  + ++Q  DGQ+ E+YSISAGL
Sbjct: 245 NDPSVKKFGVEAGGRGEAPTDNAKTLSGAGEPGILHGAFSYLLQDPDGQVVEAYSISAGL 304

Query: 305 DFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRE 364
           D+P VGP+H+Y    G   YVS+TD EAL+AF+ L   EGIIPA+ESSHALA+  K+M +
Sbjct: 305 DYPGVGPEHSYYKDEGIVKYVSVTDQEALDAFQRLSKVEGIIPAMESSHALAYLDKLMPQ 364

Query: 365 NPDKEQLLVVNLSGRGDKDIFTVHDILKARGE 396
               E ++ V LSGRGDKD+  V  +L    E
Sbjct: 365 THPDESVV-VTLSGRGDKDVQMVAKVLGEDIE 395


>UniRef50_C5V964 Tryptophan synthase, beta subunit n=2 Tax=Corynebacterium
           matruchotii RepID=C5V964_9CORY
          Length = 453

 Score =  558 bits (1439), Expect = e-157,   Method: Composition-based stats.
 Identities = 238/392 (60%), Positives = 307/392 (78%), Gaps = 3/392 (0%)

Query: 3   TLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKC 62
           TL++ YFGE+GG YVP++L P+L QLE+A+V A  DPEF  + +DL +NY GRPT +T+C
Sbjct: 14  TLIDAYFGEYGGQYVPEVLYPSLDQLEQAYVDALNDPEFLRELDDLRRNYLGRPTPITEC 73

Query: 63  QNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALA 122
            N+    N  ++LKREDLLHGGAHK NQVL QALLAKRMGKT +IAETGAGQHG+A+A+ 
Sbjct: 74  ANLPLSGNARIFLKREDLLHGGAHKGNQVLAQALLAKRMGKTRLIAETGAGQHGMATAMV 133

Query: 123 SALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS-GSATLKDACNEALRDWSGSY 181
           +AL+G++C IYMGA+DV RQ PNV+RMRLMGA+V+PV +     L DA + AL DW  S 
Sbjct: 134 AALMGMECTIYMGARDVARQQPNVYRMRLMGAKVVPVSNEHGEALSDAIDVALADWVESL 193

Query: 182 ETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMF 241
            T HY+LGTAAGPHP+P +V++FQ++I EE++ Q+LER GRLPDAV+ACVGGGSNAIG F
Sbjct: 194 GTTHYLLGTAAGPHPFPKLVKQFQKVISEESRQQMLERTGRLPDAVVACVGGGSNAIGAF 253

Query: 242 ADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSIS 301
           A+++ +  V LIGVEP G G+++G+HGAPL  G+VG+  G K+ +M   DG++  S+S+S
Sbjct: 254 AEYLPDEEVRLIGVEPAGEGLDSGKHGAPLNRGKVGVLHGSKSYVMLGSDGEVMHSHSVS 313

Query: 302 AGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKM 361
           AGLD+P VGP+HAYL  +GRA+YV ITD EAL+AF+ L  +EGIIPALESSHALA+ALK+
Sbjct: 314 AGLDYPGVGPEHAYLLDSGRAEYVGITDAEALQAFRMLSWYEGIIPALESSHALAYALKL 373

Query: 362 MREN-PDKEQL-LVVNLSGRGDKDIFTVHDIL 391
                P  E L ++VNLSGRGDKD+  V  IL
Sbjct: 374 AEHADPQGEPLNILVNLSGRGDKDVDYVRHIL 405


>UniRef50_A5UMB9 Tryptophan synthase, beta subunit, TrpB n=5 Tax=cellular organisms
           RepID=A5UMB9_METS3
          Length = 593

 Score =  557 bits (1437), Expect = e-157,   Method: Composition-based stats.
 Identities = 208/385 (54%), Positives = 279/385 (72%), Gaps = 2/385 (0%)

Query: 6   NPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNI 65
           N  +GE+GG Y+ + LM  L  LEE +     D EF  + N LLK YAGRP+ L   + +
Sbjct: 202 NGRYGEYGGQYISETLMNELIYLEEQYYHYMNDSEFVEELNTLLKEYAGRPSLLYYAKRM 261

Query: 66  TAGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASA 124
           T       +YLKREDL H GAHK N VLGQ LLAK+MGKT +IAETGAGQHGVA+A A+A
Sbjct: 262 TEDLGGAKIYLKREDLNHTGAHKINNVLGQVLLAKKMGKTRVIAETGAGQHGVATATAAA 321

Query: 125 LLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETA 184
           LL ++C +YMG  D +RQ+ NV+RM L+GA+V PV SG+ TLKDA N+A RDW G     
Sbjct: 322 LLDMECEVYMGELDTKRQALNVYRMELLGAKVHPVKSGTKTLKDAVNDAFRDWIGRVHDT 381

Query: 185 HYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADF 244
           +Y++G+  GPHP+P +VR+FQ +I  E + Q LE+EG+LPDAV+ACVGGGSNA+G F +F
Sbjct: 382 NYVIGSTMGPHPFPMMVRDFQAVISAEAREQFLEKEGKLPDAVLACVGGGSNAMGAFYNF 441

Query: 245 INETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGL 304
           I++ +V LIG E GG G++T  + A L +G++GI+ GMK+   Q E GQI E YS+SAGL
Sbjct: 442 IDDADVKLIGCEAGGKGVDTPYNAAALTNGQIGIFHGMKSIFNQGEYGQISEVYSVSAGL 501

Query: 305 DFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRE 364
           D+P VGP+HAYL    RA+YV +TD+EA+ AF+ L   EGIIPA+ES+HA+AHA+K+  +
Sbjct: 502 DYPGVGPEHAYLRDIKRAEYVPVTDEEAVNAFEYLSKMEGIIPAIESAHAVAHAMKIAPK 561

Query: 365 NPDKEQLLVVNLSGRGDKDIFTVHD 389
             DK+++++V LSGRGDKD+ ++  
Sbjct: 562 M-DKDEIIMVCLSGRGDKDVASIAK 585


>UniRef50_A8Z5Y3 Putative tryptophan synthase, beta subunit (TrpB)/anthranilate
           isomerase activity of trpC (TrpF) n=1 Tax=Candidatus
           Sulcia muelleri GWSS RepID=A8Z5Y3_SULMW
          Length = 595

 Score =  548 bits (1412), Expect = e-154,   Method: Composition-based stats.
 Identities = 183/387 (47%), Positives = 255/387 (65%), Gaps = 8/387 (2%)

Query: 6   NPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNI 65
           + ++G FGG Y+P++L   +  L+  +     +  F+ +   LL NY GRP+ L  C N+
Sbjct: 214 HGFYGNFGGAYIPEMLYNNINHLKNEYNKIINNNCFKKKLKRLLHNYVGRPSPLFYCNNL 273

Query: 66  TAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASAL 125
           +      +YLKREDL H G+HK N  +GQALLAK +GK  II+ETGAGQHGVA++   +L
Sbjct: 274 SKIYGAKIYLKREDLNHTGSHKINNTIGQALLAKEIGKKNIISETGAGQHGVATSTICSL 333

Query: 126 LGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAH 185
           LGLKC I+MG  D++RQ  NV+RM+++GA +I V+SGS TLKD+ NEA+R W  +    +
Sbjct: 334 LGLKCTIFMGEVDIKRQIQNVYRMKMLGANIIAVNSGSKTLKDSVNEAIRYWI-NNPDCY 392

Query: 186 YMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFI 245
           YM+G+A GP PYP +V  FQ +I EE K Q+ E    LP+ +IAC+GGGSNA G+F  F+
Sbjct: 393 YMIGSAVGPDPYPRMVSYFQSIISEEIKEQLKE----LPNYIIACLGGGSNAAGIFYHFL 448

Query: 246 NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLD 305
           ++  V LIGVE  G G+ T +  A ++ G  G+  G    +MQ + GQI E YSISAGLD
Sbjct: 449 DDEYVKLIGVEASGLGLNTNKTAATIQKGSRGVLHGSMTILMQDKYGQILEPYSISAGLD 508

Query: 306 FPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMREN 365
           +P +GP HA L    RA ++S+TD EA+EA   L   EGIIPALES+HA+A   K+  + 
Sbjct: 509 YPGIGPMHANLFYKNRATFISVTDFEAIEAGIELSSLEGIIPALESAHAIASLKKLSFK- 567

Query: 366 PDKEQLLVVNLSGRGDKDIFTVHDILK 392
             K  L+++N+SGRGDKD+ T    ++
Sbjct: 568 --KNDLVIINMSGRGDKDMDTYIKHIE 592


>UniRef50_D0JB95 Bifunctional phosphoribosylanthranilate isomerase/tryptophan
           synthase subunit beta n=1 Tax=Blattabacterium sp.
           (Blattella germanica) str. Bge RepID=D0JB95_BLASB
          Length = 610

 Score =  547 bits (1411), Expect = e-154,   Method: Composition-based stats.
 Identities = 189/387 (48%), Positives = 253/387 (65%), Gaps = 5/387 (1%)

Query: 6   NPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNI 65
           N Y+GEFGG ++P++L   + +L++ +       EFQ  +  +LKNYAGRPT L  C+  
Sbjct: 218 NGYYGEFGGAFIPEMLHHNITELQDQYKKFITSFEFQKLYKKILKNYAGRPTPLFFCKKY 277

Query: 66  TAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASAL 125
           +      +YLKREDL H G+HK N  +GQALLAK++GK +IIAETGAGQHGVA+A   AL
Sbjct: 278 SDKYKAKIYLKREDLNHTGSHKINNSIGQALLAKQLGKKKIIAETGAGQHGVATATTCAL 337

Query: 126 LGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAH 185
           + L+C I+MG  D+ RQ  NV RM+ +GA+VIPV SG  TLKDA NEA+R W    E+ +
Sbjct: 338 MNLECIIFMGETDIHRQYTNVLRMKSLGAKVIPVCSGDKTLKDAVNEAIRYWISHPES-Y 396

Query: 186 YMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREG-RLPDAVIACVGGGSNAIGMFADF 244
           Y++G+  GPHPYP +V + Q +I EE K Q+ E+EG   P+ V+AC+GGGSNA G F  F
Sbjct: 397 YLIGSTVGPHPYPQMVADIQSIISEEIKIQLKEKEGSSFPNYVVACIGGGSNAAGSFYHF 456

Query: 245 INETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGL 304
           ++  +V L+ VE  G G+ T +  A +  G  GI  G    ++Q EDGQ+  ++SISAGL
Sbjct: 457 LDNDSVNLVAVEAAGLGVNTKKTAASIHCGSRGILHGSMTMLLQNEDGQVLPAHSISAGL 516

Query: 305 DFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRE 364
           D+P +GP  A L    R +++  TD+EAL+A   L   EGIIPALESSHALA ALK +  
Sbjct: 517 DYPGIGPMFANLFVKKRVNFLHSTDEEALQAGYELTRLEGIIPALESSHALA-ALKNIP- 574

Query: 365 NPDKEQLLVVNLSGRGDKDIFTVHDIL 391
              K  ++VV LSGRGDKDI       
Sbjct: 575 -FKKMDVVVVTLSGRGDKDINVYDKFF 600


>UniRef50_D1HPU5 Whole genome shotgun sequence of line PN40024,
           scaffold_116.assembly12x (Fragment) n=2 Tax=Vitis
           vinifera RepID=D1HPU5_VITVI
          Length = 407

 Score =  541 bits (1393), Expect = e-152,   Method: Composition-based stats.
 Identities = 194/393 (49%), Positives = 263/393 (66%), Gaps = 10/393 (2%)

Query: 7   PYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNIT 66
             FG FGG +VP+ LM  L +LE  F     DPEFQ +    L++Y GR T L   Q +T
Sbjct: 6   GKFGRFGGKFVPETLMTCLSKLEAEFNLVLHDPEFQEELATALRDYVGRETPLYFAQRLT 65

Query: 67  A------GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASA 120
                  G    +YLKREDL HGGAHK N  + QA++AKRMG+T I+A TGAGQHGVA+A
Sbjct: 66  DHYKNESGCGPEIYLKREDLNHGGAHKINNAIAQAMIAKRMGRTSIVAATGAGQHGVATA 125

Query: 121 LASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGS 180
            A A L LKC I MG  D+ERQ+ NV  M+L+GAEV  V       K+A +EA+R+W G+
Sbjct: 126 AACAKLSLKCTIVMGTLDMERQASNVLLMKLLGAEVKSVD---GNFKNATSEAIREWVGN 182

Query: 181 YETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGM 240
            ET ++++GTA GPHP P++VREFQ +IG+ET+ Q +ER GR PD ++ACVG GSNA+G+
Sbjct: 183 LETNYFLIGTAVGPHPCPSMVREFQSIIGKETRRQAMERWGRKPDVLVACVGSGSNALGL 242

Query: 241 FADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSI 300
           F +FI + +V +IGVE  G G+E+G+H A L  G VG+Y G  + ++Q E+GQI   +SI
Sbjct: 243 FHEFIADEDVRMIGVEAAGFGLESGKHSATLAKGEVGVYHGAMSYLLQDEEGQIVGPHSI 302

Query: 301 SAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALK 360
             G+++P V P+ ++L  TGR +  S+TD EA++A++ LC  EGI PALE+SHALA   K
Sbjct: 303 GVGMEYPGVSPELSFLKETGRVESYSVTDQEAVDAYQLLCRLEGIFPALEASHALAFLDK 362

Query: 361 MMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
           +    PD  +++ VN SGRGDKD  TV  + + 
Sbjct: 363 LCPTLPDGGKVV-VNCSGRGDKDAPTVFRLTQG 394


>UniRef50_Q2S700 Tryptophan synthase, beta subunit n=6 Tax=Bacteria
           RepID=Q2S700_HAHCH
          Length = 426

 Score =  536 bits (1382), Expect = e-151,   Method: Composition-based stats.
 Identities = 207/390 (53%), Positives = 265/390 (67%), Gaps = 4/390 (1%)

Query: 6   NPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNI 65
           N  FG FGG Y P+IL PAL +LE  F S + DP+F  ++  L + ++GRPT LT C+ +
Sbjct: 6   NGMFGSFGGRYAPEILTPALIELERLFFSLRDDPDFWREYQTLAQQFSGRPTPLTPCERL 65

Query: 66  T-AGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASA 124
           +       ++LKREDL H GAHK N VLGQ LL +RMGK  +IAETGAGQHG+A+A+ +A
Sbjct: 66  SREIGGAQIWLKREDLNHSGAHKVNNVLGQGLLVRRMGKRRVIAETGAGQHGLATAIMAA 125

Query: 125 LLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETA 184
            LGL+CRIYMG  D+ERQ  NVF MR +GAEVIPV +G+ TLK+A +EALRDW+ S+E  
Sbjct: 126 RLGLECRIYMGEDDIERQYGNVFWMRRLGAEVIPVATGARTLKEAMDEALRDWAASFEDT 185

Query: 185 HYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADF 244
           HY+LGTA GP P+P +V  FQ +IG+E + Q L + GR PD+V+ACVGGGSNA+G FA F
Sbjct: 186 HYVLGTACGPAPFPELVAYFQSIIGKELQQQALSQIGRNPDSVVACVGGGSNALGAFAPF 245

Query: 245 INETNVGLIGVEPGGHGIETGEHGAPLKHGR--VGIYFGMKAPMMQTEDGQIEESYSISA 302
           I   +V L+GVE GG   E G+H   L+ G    GI  G K   +Q  DGQ+  ++S++A
Sbjct: 246 IERHDVELVGVEAGGRSREEGQHSIRLQEGTGEDGIAQGFKTLFLQDADGQLGHTHSVAA 305

Query: 303 GLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMM 362
           GLD+  V P  A L   GR    S TD+EAL AF+TL  +EGIIPALESSHALA   +  
Sbjct: 306 GLDYVGVSPILADLTQRGRLTPDSATDEEALAAFETLLRYEGIIPALESSHALAGGFRRA 365

Query: 363 RENPDKEQLLVVNLSGRGDKDIFTVHDILK 392
            +    +Q +V+NLSGRGDKDIF V     
Sbjct: 366 AQM-SPQQHMVINLSGRGDKDIFNVARAFP 394


>UniRef50_Q7VGA7 Tryptophan synthase beta chain n=4 Tax=Proteobacteria
           RepID=TRPB_HELHP
          Length = 420

 Score =  528 bits (1361), Expect = e-148,   Method: Composition-based stats.
 Identities = 194/399 (48%), Positives = 256/399 (64%), Gaps = 11/399 (2%)

Query: 2   TTLLNPYFGE-------FGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAG 54
           T   N YFGE       FGG Y+P+IL+PAL++LE+A+        ++ +   L K++ G
Sbjct: 7   TESKNGYFGEAKGGNHAFGGQYIPEILLPALKELEKAYHGVFVSKAYKKELKSLFKHFVG 66

Query: 55  RPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQ 114
           RPT L    N +      +YLK E L + GAHK N  LGQ LLAK M K  +IAETGAGQ
Sbjct: 67  RPTPLIYAHNASKILKNDIYLKFEGLANTGAHKINNALGQVLLAKHMKKKRVIAETGAGQ 126

Query: 115 HGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEAL 174
           HG+A+A A A LGL+C I+MG  D+ RQ PNVF M L GA+V  V SGS TLKDA NEAL
Sbjct: 127 HGLATAAACARLGLECEIFMGEIDIARQRPNVFNMELFGAKVHSVSSGSKTLKDAVNEAL 186

Query: 175 RDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGG 234
           R+WS   + + Y+LG+A GP+PYP IVR+ Q +I +E K Q       LPD ++ACVGGG
Sbjct: 187 REWSKRSDDSFYVLGSALGPYPYPDIVRDLQSVISKELKKQTKAYFSSLPDILVACVGGG 246

Query: 235 SNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLK--HGRVGIYFGMKAPMMQTEDG 292
           SNA+G F  ++ E  V LIGVE GG G + GE+   +   +   GI  G K+  +Q +DG
Sbjct: 247 SNAMGFFTHYLKEERVRLIGVEAGGIGDKEGENAIRINTINASEGIAQGYKSLFLQDKDG 306

Query: 293 QIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESS 352
           Q+ +++SISAGLD+  +GPQ A+L   GR ++ S TD EALEA      +EGIIPALESS
Sbjct: 307 QLSDTHSISAGLDYAGIGPQLAHLYEVGRVEFQSATDKEALEALSFFAQYEGIIPALESS 366

Query: 353 HALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDIL 391
           HALA  +++ ++   K+  ++ N+SGRGDKDIF     L
Sbjct: 367 HALAAVIRLCKDIKGKK--IIANISGRGDKDIFITAKAL 403


>UniRef50_C0NSJ2 Bifunctional tryptophan synthase TRPB n=1 Tax=Ajellomyces
           capsulatus G186AR RepID=C0NSJ2_AJECG
          Length = 594

 Score =  522 bits (1346), Expect = e-147,   Method: Composition-based stats.
 Identities = 189/389 (48%), Positives = 248/389 (63%), Gaps = 47/389 (12%)

Query: 7   PYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNIT 66
             FGEFGG YVP+ LM  L +LE                                     
Sbjct: 244 ARFGEFGGQYVPESLMDNLLELEA------------------------------------ 267

Query: 67  AGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALL 126
                     REDL H G+HK N  LGQ LLA+R+GKT IIAETGAGQHGVA+A   A  
Sbjct: 268 ----------REDLNHTGSHKINNALGQVLLARRLGKTRIIAETGAGQHGVATATVCAKF 317

Query: 127 GLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHY 186
           G++C IYMGA+DV RQ+ NVFR++L+GA+V+ V +GS TL+DA NEALR W    +T HY
Sbjct: 318 GMECVIYMGAEDVRRQALNVFRIKLLGAKVVAVEAGSRTLRDAVNEALRAWVVHLDTTHY 377

Query: 187 MLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFIN 246
           ++G+A GPHP+PTIVR  Q +IGEETK Q+ +  GRLPDAV+ACVGGGSNA+GMF  F  
Sbjct: 378 VIGSAIGPHPFPTIVRTLQSVIGEETKEQMQKLTGRLPDAVVACVGGGSNAVGMFYPFTK 437

Query: 247 ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDF 306
           + +V L+GVE GG G +T  H A L HG  G+  G++  ++Q EDGQI +++SISAGLD+
Sbjct: 438 DPSVRLLGVEAGGDGTDTARHSATLSHGSKGVLHGVRTYILQNEDGQIADTHSISAGLDY 497

Query: 307 PSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENP 366
           P VGP+ +      RA +++ TD +AL+ F+ +   EGIIPALESSHA+  A+++ +   
Sbjct: 498 PGVGPELSSWKDQSRAQFIAATDAQALQGFRLITELEGIIPALESSHAVFGAVELAKTMK 557

Query: 367 DKEQLLVVNLSGRGDKDIFTVHDILKARG 395
             E +++ NLSGRGDKD+ +V D L   G
Sbjct: 558 KGENIVL-NLSGRGDKDVQSVADALPEIG 585


>UniRef50_D2VKV7 Predicted protein n=1 Tax=Naegleria gruberi RepID=D2VKV7_NAEGR
          Length = 434

 Score =  522 bits (1346), Expect = e-147,   Method: Composition-based stats.
 Identities = 195/407 (47%), Positives = 266/407 (65%), Gaps = 23/407 (5%)

Query: 5   LNPYFG-------EFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPT 57
           +N  +G       +FGG +VP  L   L +L + F+  + D EF  +F DLL+++ GRPT
Sbjct: 31  MNGIYGITKDESCQFGGCHVPPQLQKVLERLRDEFLKYKDDEEFNKEFRDLLRDFVGRPT 90

Query: 58  ALTKCQNITA--GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
            L+  +N     GTN  +YLKRED  H G+HK N  +GQ LLAKRMG   IIAETGAGQH
Sbjct: 91  PLSPARNFAKQLGTNAKIYLKREDTAHLGSHKINNCIGQILLAKRMGAKRIIAETGAGQH 150

Query: 116 GVASALASALLG-LKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEAL 174
           G A A   AL G ++C IYMGA+D  RQS NVFRM+++GA+VIPV  G   L+DA +EAL
Sbjct: 151 GSAVAAVCALFGNIECVIYMGAEDCRRQSLNVFRMQMLGAKVIPVTKGQGRLRDAVDEAL 210

Query: 175 RDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGG 234
            D   +YE   Y+LG+A GP P+P +V+ FQ +I EE++ QIL+ E +LP  VIACVGGG
Sbjct: 211 GDLVQNYENTFYLLGSAVGPCPFPNMVKHFQSVISEESRQQILQAENKLPTMVIACVGGG 270

Query: 235 SNAIGMFADFI---NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTED 291
           SNAIG F+ ++    +  V L+G+EP             L  G   I  G K+  +  E+
Sbjct: 271 SNAIGAFSHYLRKGEDEKVRLLGIEPI--------EAPTLTEGVPYILHGFKSLCLLDEN 322

Query: 292 GQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALES 351
           G+ +++YS++AGLD+PSVG  H+YL S GR +Y +++  + LEAF  L   EGIIPALES
Sbjct: 323 GEPKKTYSVAAGLDYPSVGSIHSYLKSIGRCEYYTVSKKQVLEAFMLLSKSEGIIPALES 382

Query: 352 SHALAHALKMMRENPDK-EQLLVVNLSGRGDKDIFTVHDILKARGEI 397
           SHALA+ ++M + N  K + ++VVNLSGRGDKD+  V+D++K +GE 
Sbjct: 383 SHALAYVVEMAKNNQLKDDDIVVVNLSGRGDKDVEQVYDMIK-KGEF 428


>UniRef50_B2TM49 Tryptophan synthase beta chain n=40 Tax=cellular organisms
           RepID=TRPB_CLOBB
          Length = 405

 Score =  519 bits (1336), Expect = e-145,   Method: Composition-based stats.
 Identities = 182/385 (47%), Positives = 259/385 (67%), Gaps = 4/385 (1%)

Query: 6   NPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNI 65
           N  FG++GG Y+   L+PA  ++ +A+ +     +F  +   + K + GRPT +  C+ +
Sbjct: 14  NGRFGQYGGAYLTAELIPAFEEIADAYQTICHSSQFINELRRIRKEFQGRPTPVYHCERL 73

Query: 66  TAGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASA 124
           +       +YLKREDL H GAHK N  +G+ LLAK MGK  +IAETGAGQHGVA A A+A
Sbjct: 74  SRAIGNCQIYLKREDLNHTGAHKLNHCMGEGLLAKFMGKKRLIAETGAGQHGVALATAAA 133

Query: 125 LLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETA 184
             GL+C I+MG  D+ +Q+PNV RM+++GA+V+PV  G  TLK+A + A   ++ +Y+ +
Sbjct: 134 FFGLECEIHMGEVDIAKQAPNVTRMKILGAKVVPVTHGLKTLKEAVDSAFDSYAKNYKDS 193

Query: 185 HYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADF 244
            Y +G+A GPHP+P +VR+FQ ++G E K Q  E  G LPD V ACVGGGSNA GMF  F
Sbjct: 194 IYCIGSALGPHPFPLMVRDFQAVVGYEAKDQFKEMTGFLPDVVTACVGGGSNAAGMFIPF 253

Query: 245 INETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGL 304
           + E  V +IG+EP G G + G+H A +K+G  G+  G ++ M++ ++G     YSI++GL
Sbjct: 254 LEEP-VDIIGIEPLGRGEKLGDHAASMKYGEKGVMHGFESIMLKDKNGDPAPVYSIASGL 312

Query: 305 DFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRE 364
           D+PSVGP+HA+L   GR DY  I D+EA+EAF  L  +EGIIPA+ESSHA+A+A+K   E
Sbjct: 313 DYPSVGPEHAFLRELGRVDYKVINDEEAMEAFFKLSRYEGIIPAIESSHAVAYAMKKAEE 372

Query: 365 NPDKEQLLVVNLSGRGDKDIFTVHD 389
              K+  ++V LSGRGDKDI  + +
Sbjct: 373 M--KQGSILVCLSGRGDKDIDYIVE 395


>UniRef50_B2KCI5 Tryptophan synthase beta chain n=2 Tax=Bacteria RepID=TRPB_ELUMP
          Length = 412

 Score =  518 bits (1335), Expect = e-145,   Method: Composition-based stats.
 Identities = 188/389 (48%), Positives = 266/389 (68%), Gaps = 2/389 (0%)

Query: 6   NPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNI 65
           + ++G +GG++VP+ L+  L ++ + F +     EFQ +     KNY GRP+ L    NI
Sbjct: 21  HGFYGIYGGVFVPKELIVPLAEIADCFNNTAFTKEFQDELFYYYKNYVGRPSPLYYAANI 80

Query: 66  TAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASAL 125
           + G    +YLKREDL H GAHK N  +G+ LLAK+MGK  +IAETGAGQHG+A A A+AL
Sbjct: 81  SCG-GAKIYLKREDLNHTGAHKINHCIGEVLLAKKMGKKRVIAETGAGQHGIAIATAAAL 139

Query: 126 LGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAH 185
           LG++C IYMG +DV+++ PNV +++ +GA+V+ V SG+  LK+A + A  D+    ET  
Sbjct: 140 LGIECVIYMGEQDVKKEYPNVLKIKTLGAKVVCVGSGAKGLKEAVDAAFDDYLKDPETQM 199

Query: 186 YMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFI 245
           Y +G+  GPHP+P +V  FQ ++G+E + Q LE+EGRLPD V+ACVGGGSN++G+F+ F 
Sbjct: 200 YAIGSVVGPHPFPLMVASFQSIVGKEAREQFLEQEGRLPDNVVACVGGGSNSMGIFSGFF 259

Query: 246 NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLD 305
            +  V L GVEP G G+ETG H APL  GRVG+  G K   MQ + G    ++S+++GLD
Sbjct: 260 ADKTVKLTGVEPAGKGLETGLHAAPLAKGRVGVVHGFKCYFMQDDKGNPMGTHSVASGLD 319

Query: 306 FPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMREN 365
           +  VGPQH YL  +GR  Y S  DDEA++AF  L   EGIIPALES+HA+A+ALK+ +E 
Sbjct: 320 YLGVGPQHCYLKDSGRVTYRSACDDEAVDAFFMLSRKEGIIPALESAHAVAYALKLSKEL 379

Query: 366 PDKEQLLVVNLSGRGDKDIFTVHDILKAR 394
             K++ ++VNLSGRG+KD+  V  +   +
Sbjct: 380 -GKDKSILVNLSGRGEKDLDYVLSLYGKK 407


>UniRef50_C1FGK1 Predicted protein n=14 Tax=cellular organisms RepID=C1FGK1_9CHLO
          Length = 444

 Score =  516 bits (1328), Expect = e-145,   Method: Composition-based stats.
 Identities = 181/392 (46%), Positives = 259/392 (66%), Gaps = 4/392 (1%)

Query: 6   NPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNI 65
           + YFGE+GG ++P  L+P + +++  +   ++DP F A+   L K++ GRP+ +  C+ +
Sbjct: 34  DGYFGEYGGAFLPPPLVPIIDEIKAKYNELKEDPSFWAELRLLEKHFTGRPSPILHCERL 93

Query: 66  TAG-TNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASA 124
           +       +YLKREDL H GAHK N  LG+ALLAK+MGK ++IAETGAGQHGVA A A+A
Sbjct: 94  SEKIGGAQIYLKREDLNHTGAHKINHCLGEALLAKKMGKKKLIAETGAGQHGVALATAAA 153

Query: 125 LLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETA 184
           L+GL+C IYMG  D+ ++ PNV RM+++GA VIP   G  TLK+A + A   +     T 
Sbjct: 154 LVGLECDIYMGEVDMAKERPNVVRMKILGANVIPASHGLKTLKEAVDAAFGAYMEDPVTQ 213

Query: 185 HYMLGTAAGPHPYPTIVREFQRMIGEETKAQILER-EGRLPDAVIACVGGGSNAIGMFAD 243
            Y +G+  GPHP+P +VR+FQ ++G E K Q  E   G+LPD ++ACVGGG NAIG+F  
Sbjct: 214 FYAIGSVVGPHPFPAMVRDFQSVVGREAKEQFKELTGGKLPDNLVACVGGGCNAIGLFTA 273

Query: 244 FINETNVGLIGVEPGGHGIET-GEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISA 302
           F+ +  V + GVEP G  ++T G+H A L  G  G+  G K  ++Q E G+     + ++
Sbjct: 274 FLGDEKVKMFGVEPSGTDLKTVGKHAATLTLGTPGVIHGFKCVLLQDEGGEPAAVNTCAS 333

Query: 303 GLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMM 362
           GLD+P VGPQH YL   GR  Y + TD E ++AF +L   +GIIPALESSHA+A+A+K+ 
Sbjct: 334 GLDYPGVGPQHCYLKDIGRVKYETATDVECVDAFMSLARDQGIIPALESSHAVAYAIKLA 393

Query: 363 RENPDKEQLLVVNLSGRGDKDIFTVHDILKAR 394
           +  P K + ++VNLSGRGDKD+  V +   A+
Sbjct: 394 KTLP-KTETILVNLSGRGDKDVDYVVENFGAK 424


>UniRef50_Q822W9 Tryptophan synthase beta chain 1 n=8 Tax=Bacteria RepID=TRPB1_CHLCV
          Length = 412

 Score =  512 bits (1320), Expect = e-144,   Method: Composition-based stats.
 Identities = 202/384 (52%), Positives = 270/384 (70%), Gaps = 2/384 (0%)

Query: 12  FGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGT-N 70
           +GG YVP  L+  L  L+ ++   +KDP+F+  F+ +LKNYAGRPT LT+ +N +     
Sbjct: 27  YGGQYVPLELVKPLEDLDRSYEQLKKDPQFRETFHHILKNYAGRPTPLTEVKNFSRAING 86

Query: 71  TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKC 130
             ++LKREDLLH GAHK N VLGQ L+AK  GKT ++AETGAGQHGVA A A+A LG++C
Sbjct: 87  PRIFLKREDLLHTGAHKINNVLGQCLIAKFQGKTRVVAETGAGQHGVALAAAAAYLGMEC 146

Query: 131 RIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGT 190
            I+MG  D+ RQ PNV R+R++GAEV+ V  G++ LK+A + A+ D+   ++  H+ +G+
Sbjct: 147 VIFMGETDINRQKPNVDRIRVLGAEVVSVKRGNSGLKEAVDAAIEDFIFKHDHTHFCIGS 206

Query: 191 AAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNV 250
           A GP+PYP IVR+FQ +I  E K+QI E   R PD +IACVGGGSNAIG F  FI  T V
Sbjct: 207 ALGPYPYPKIVRDFQSVISLEVKSQIKEYTDRDPDILIACVGGGSNAIGFFHHFIPNTKV 266

Query: 251 GLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVG 310
            L+GVE GG G+E+G+H A    G+ G+  G  + ++Q EDG   ++YSISAGLD+ SVG
Sbjct: 267 KLVGVEGGGLGVESGKHAARFATGKPGVVHGFHSYVLQDEDGNCADTYSISAGLDYVSVG 326

Query: 311 PQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQ 370
           P HA ++ +GRA Y   TDDEALEAF+ L   EGIIPALESSHALAH +K+     DK+ 
Sbjct: 327 PTHAEMHESGRAQYTYATDDEALEAFRLLSKTEGIIPALESSHALAHMIKIAPSL-DKDT 385

Query: 371 LLVVNLSGRGDKDIFTVHDILKAR 394
           + +VNLSGRGDKD+  + D+ K +
Sbjct: 386 IAIVNLSGRGDKDLSQIIDLDKRK 409


>UniRef50_B0R332 Tryptophan synthase beta chain n=8 Tax=cellular organisms
           RepID=TRPB_HALS3
          Length = 430

 Score =  503 bits (1296), Expect = e-141,   Method: Composition-based stats.
 Identities = 194/404 (48%), Positives = 255/404 (63%), Gaps = 27/404 (6%)

Query: 9   FGEFGGMYVPQILMPALRQLEEAFVSAQKDPE--FQAQFNDLLKNYAGRPTALTKCQNIT 66
           FG++GG YVP++LMPA+ +L +A+     D E  F   F   ++++ GRPT LT    ++
Sbjct: 15  FGDYGGQYVPEVLMPAVEELTDAYERYVLDNEDGFVDDFRQRIRSFGGRPTPLTHAPTLS 74

Query: 67  AGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALL 126
                 +YLKREDLLHGGAHK N  LGQ LLAK MGK  I+AETGAGQHG A+A+A A L
Sbjct: 75  QRHGVDVYLKREDLLHGGAHKLNNALGQVLLAKYMGKDRIVAETGAGQHGTATAMACAAL 134

Query: 127 GLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHY 186
            + C IYMG  DV RQ PNVFRMRL  A+V PV  GS TLK+A NE +RDW+ +    HY
Sbjct: 135 EMPCEIYMGRTDVNRQRPNVFRMRLHDADVNPVTVGSGTLKEAINETMRDWATNVADTHY 194

Query: 187 MLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFI- 245
           ++G+  GPHP+P++VR+FQ +I EE +AQ  E+ G LP AVIAC GGGSN +G F  F+ 
Sbjct: 195 VIGSVVGPHPFPSMVRDFQAIISEELRAQSREQLGELPAAVIACAGGGSNTMGAFGAFVG 254

Query: 246 -------------NETNVGLIGVEPGGH--GIET----GEHGAPLKHGRVGIYFGMKAPM 286
                           +V L+ VE GG   G++       + A L  G  G+  G +  +
Sbjct: 255 SASLPGAPAGTHEPAPDVDLLAVEAGGSRLGVDDDAGYAPNSASLSTGTEGVLHGARTKL 314

Query: 287 MQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGII 346
           +QTE GQI ES+S+SAGLD+  VGP+ A+L  TGR    ++ DD AL AF  L   EG+I
Sbjct: 315 LQTETGQIVESHSVSAGLDYAGVGPELAHLVDTGRITPTNVDDDAALAAFHRLSRDEGVI 374

Query: 347 PALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDI 390
           PALE+SHA+A   +      D +  +VVN+SGRGDKD+ TV + 
Sbjct: 375 PALETSHAVAALDQY-----DGDGPVVVNVSGRGDKDLDTVIEA 413


>UniRef50_B0ZSJ6 Tryptophan synthase beta subunit n=3 Tax=rosids RepID=B0ZSJ6_SOYBN
          Length = 461

 Score =  503 bits (1295), Expect = e-141,   Method: Composition-based stats.
 Identities = 175/391 (44%), Positives = 256/391 (65%), Gaps = 11/391 (2%)

Query: 6   NPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNI 65
           +  FG FGG +VP+ L+ +L QLE  F +A +D  FQA+  + L++YAGR T L   + +
Sbjct: 70  SGKFGRFGGKFVPETLVASLTQLEAEFKNALRDHAFQAELAEALRDYAGRETPLYHAKRL 129

Query: 66  TA-------GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVA 118
           +        G    +YLKREDL H G+HK N  L QA++AKRMG   ++  TG+GQHG+A
Sbjct: 130 SEYYKSVNNGKGPDIYLKREDLNHSGSHKMNNALAQAMIAKRMGCKSVVTATGSGQHGLA 189

Query: 119 SALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWS 178
           +A A A L L C ++M  KD+ RQ  NV  ++L+GA+V  V  G     DA +EA R W 
Sbjct: 190 TAAACAKLALDCTVFMADKDIHRQYSNVRLIKLLGAQVEAVDGG---FTDAASEAFRYWV 246

Query: 179 GSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAI 238
           G  E  +++ G+A GPHP PT+VREFQ +IG+ET+ Q LE+ G  PD ++A VG GSNA+
Sbjct: 247 GDLENRYHLSGSAVGPHPCPTMVREFQSVIGKETRMQALEKWGGKPDVLVASVGTGSNAL 306

Query: 239 GMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESY 298
           G+F +FI + +V  +GVE GG G+E+G+H + L  G VG Y G  + ++Q +DGQI   +
Sbjct: 307 GLFHEFIADKDVRFVGVEAGGLGLESGKHSSTLTTGEVGAYHGAISYLLQDQDGQIIHPH 366

Query: 299 SISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHA 358
           SI+AG+++P VGP+ ++L  +GRA++    D+EAL+A++ LC  EGI P+LE++HALA  
Sbjct: 367 SIAAGMEYPGVGPELSFLKESGRAEFCVANDEEALDAYQRLCKLEGIFPSLEAAHALAIL 426

Query: 359 LKMMRENPDKEQLLVVNLSGRGDKDIFTVHD 389
            K++    +  +++ VN SGRGDKD   V +
Sbjct: 427 DKLVPTLCNGTKVV-VNCSGRGDKDAAIVFN 456


>UniRef50_Q0RGR3 Tryptophan synthase, beta protein n=2 Tax=Actinomycetales
           RepID=Q0RGR3_FRAAA
          Length = 487

 Score =  496 bits (1277), Expect = e-139,   Method: Composition-based stats.
 Identities = 197/390 (50%), Positives = 257/390 (65%), Gaps = 13/390 (3%)

Query: 5   LNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQN 64
           ++  FGEFGG YVP+ L+ A   LE A+  A+ DP F  Q + LL  YAGRPT +T    
Sbjct: 108 VSGRFGEFGGRYVPEALVSACEDLEAAYRDARSDPSFTQQLDHLLSVYAGRPTPVTPANR 167

Query: 65  ITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASA 124
           ++      L LKREDL H G+HK N VLGQ LLA+RMGK  ++AETGAGQHGVA+A   A
Sbjct: 168 LSEELGVHLLLKREDLAHTGSHKINNVLGQGLLAQRMGKKRLLAETGAGQHGVATATIGA 227

Query: 125 LLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETA 184
           LLGL   +YMG  D++RQ+ NVFRM L+GA V+PV SG+ TLKDAC+EALR W    + A
Sbjct: 228 LLGLDVVVYMGEADIQRQALNVFRMELLGATVVPVTSGTRTLKDACSEALRQWVTQVDEA 287

Query: 185 HYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGR-LPDAVIACVGGGSNAIGMFAD 243
           HY +G+  GPHPYP +VREFQR+IG E +AQ      + +PD V ACVGGGSNA G FA 
Sbjct: 288 HYCIGSTMGPHPYPWMVREFQRVIGTEARAQCAGLLRQGVPDVVTACVGGGSNAAGTFAG 347

Query: 244 FINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAG 303
           F+ +T   L+GVE  G        GA +  G  GI  G  + ++Q EDGQ+ E++SISAG
Sbjct: 348 FV-DTPARLVGVEAAG--------GAAMTDGLPGILHGFYSNILQDEDGQVREAHSISAG 398

Query: 304 LDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMR 363
           LD+P +GP+HA L ++GRA+YV+  D+E + A   L   EGI+PALES+HALA  ++   
Sbjct: 399 LDYPGIGPEHAGLGTSGRAEYVTANDEEVVSAVVRLARAEGILPALESAHALAWIIRAAE 458

Query: 364 --ENPDKEQLLVVNLSGRGDKDIFTVHDIL 391
             E P     +++ LSGRGDKD   +  ++
Sbjct: 459 SGEIPYGST-VLMTLSGRGDKDAEQLRRLV 487


>UniRef50_B7G4U3 Tryptophan synthase, beta chain n=3 Tax=cellular organisms
           RepID=B7G4U3_PHATR
          Length = 385

 Score =  479 bits (1232), Expect = e-133,   Method: Composition-based stats.
 Identities = 167/388 (43%), Positives = 234/388 (60%), Gaps = 21/388 (5%)

Query: 6   NPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNI 65
           + YFGE+GG  +P  L+  + ++ E++    +   FQ + + L K++ GRP+ +   + +
Sbjct: 17  DGYFGEYGGQQLPPQLVEIMNEISESYEKLIRTDAFQIELDSLNKDFIGRPSPIFYARRL 76

Query: 66  TAG-TNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASA 124
           T       ++LKREDL H GAHK N  LG+ALLAK MGKT+++AETGAGQHGVA A A A
Sbjct: 77  TEKIGGARIFLKREDLNHTGAHKINHCLGEALLAKHMGKTKVLAETGAGQHGVALATACA 136

Query: 125 LLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETA 184
           L+G++C I+MG  DVE+++PNV +MR++G ++I V  G+ TLKDA +    ++       
Sbjct: 137 LIGIECEIHMGQVDVEKEAPNVTKMRILGCKLITVTRGTRTLKDAVDSVFEEYLKDPVNY 196

Query: 185 HYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADF 244
            Y +G+                      KA      G LPDA++AC GGG NA G+F  F
Sbjct: 197 FYAIGSVI-------------------FKASWDLEGGALPDAIVACGGGGCNARGIFTAF 237

Query: 245 INETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGL 304
           + +  V LIGVEP G G+ET +H A +  G  G   GM    +Q E G+    YSI++GL
Sbjct: 238 LEDPEVQLIGVEPAGRGLETSDHAATMTLGVKGSIHGMNCYNLQDETGEPLPVYSIASGL 297

Query: 305 DFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRE 364
           D+P VGPQH  L   GR  YV++TD E L+AF  L   EGIIPALES+HA+A+A K+  E
Sbjct: 298 DYPGVGPQHCLLKDIGRTKYVAVTDQECLDAFMQLSRVEGIIPALESAHAVAYATKLAVE 357

Query: 365 NPDKEQLLVVNLSGRGDKDIFTVHDILK 392
               +  ++VNLSGRGDKD   V + L+
Sbjct: 358 IGPGKT-ILVNLSGRGDKDADFVANRLQ 384


>UniRef50_B8MZR1 Trytophan synthase alpha subunit, putative n=2 Tax=Leotiomyceta
           RepID=B8MZR1_ASPFN
          Length = 641

 Score =  479 bits (1232), Expect = e-133,   Method: Composition-based stats.
 Identities = 163/390 (41%), Positives = 222/390 (56%), Gaps = 55/390 (14%)

Query: 7   PYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNIT 66
             FG FGG Y P+ L   L +LE  F +A  DP F  ++      Y GRP++L +   +T
Sbjct: 297 GRFGIFGGQYAPEALTTCLAELEAGFQAALDDPTFWEEYRSYYP-YMGRPSSLHQATRLT 355

Query: 67  AG-TNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASAL 125
                  ++LKREDL H G+HK N  LGQ L+A                           
Sbjct: 356 EHVGGANIWLKREDLNHTGSHKINNALGQILIA--------------------------- 388

Query: 126 LGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAH 185
                                   R +GA VIPV SGS TL+DA NEA R W    +T H
Sbjct: 389 ------------------------RRLGATVIPVESGSRTLRDAVNEAFRAWIVRLDTTH 424

Query: 186 YMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFI 245
           Y++G+A GPHP+PT+VR FQ +IG ETKAQ+ E  G+ PDAV+ACVGGGSN++GMF  F 
Sbjct: 425 YIIGSAIGPHPFPTMVRTFQSVIGNETKAQMQEL-GKSPDAVVACVGGGSNSVGMFYPFS 483

Query: 246 NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLD 305
            + +V L+GVE  G G++T  H A L  G VG+  G++  ++Q E GQI +++SISAGLD
Sbjct: 484 KDLSVQLVGVEAAGDGLDTDRHSATLTGGSVGVLHGVRTYILQDEHGQISDTHSISAGLD 543

Query: 306 FPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMREN 365
           +P VGP+ A+   + RA ++S TD +A E F+ L   EGIIPALE+SHA+  A++  ++ 
Sbjct: 544 YPGVGPELAHWKESKRATFLSATDAQAFEGFRLLSQLEGIIPALETSHAVWGAIQTAKKL 603

Query: 366 PDKEQLLVVNLSGRGDKDIFTVHDILKARG 395
              + L++  LSGRGDKD+ +V D L   G
Sbjct: 604 GPGKDLVL-CLSGRGDKDVQSVADGLPTIG 632


>UniRef50_C0QZH7 Tryptophan synthase beta subunit n=4 Tax=Bacteria
           RepID=C0QZH7_BRAHW
          Length = 417

 Score =  471 bits (1212), Expect = e-131,   Method: Composition-based stats.
 Identities = 183/379 (48%), Positives = 240/379 (63%), Gaps = 5/379 (1%)

Query: 17  VPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAG-TNTTLYL 75
           VP+ L   L +LEEAF+    D EF ++  +L  ++ GRPT L   +N++       +Y+
Sbjct: 17  VPEALEKLLIELEEAFLHYINDKEFLSELEELRADFIGRPTPLMYAKNLSEKIGGAKIYV 76

Query: 76  KREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMG 135
           K E L H GAHK N  +GQALLAK+MGK +IIAETGAGQHG+A+A A A LGL+C IYMG
Sbjct: 77  KLEGLAHTGAHKINNSIGQALLAKKMGKKKIIAETGAGQHGLATAAACAKLGLECSIYMG 136

Query: 136 AKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPH 195
             DV+RQ PNV  M L GA V+ V  G   LKDA + AL DW    +  HY+LG+A GP 
Sbjct: 137 EIDVKRQQPNVASMELYGANVVSVTKGGRGLKDAVDMALEDWVKDLKDTHYLLGSAVGPS 196

Query: 196 PYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGV 255
           PYP IVR FQ +IG E   QI E+   +  A+IACVGGGSNAIG F  FI   N  LI V
Sbjct: 197 PYPDIVRTFQSVIGRELDKQIQEKNLNV-KALIACVGGGSNAIGFFEPFIERENPKLIAV 255

Query: 256 EPGGHGIETGEHGAPLK--HGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQH 313
           E GG  +  GE+   ++  + +     G  +  +  E+G+I E+ SISAGLD+P VGPQ 
Sbjct: 256 EAGGISMNLGENAIRMQNPYAKDVAAQGYMSKFILKENGEISETMSISAGLDYPGVGPQL 315

Query: 314 AYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLV 373
           AYL  +GR ++   TD EA+ A K    HEG+I ALES+HA A A++  ++   K+ +++
Sbjct: 316 AYLGESGRIEFTYATDKEAINAVKEFASHEGVIFALESAHAGAKAIEYAKQY-SKDDVII 374

Query: 374 VNLSGRGDKDIFTVHDILK 392
           VN+SGRGDKDIF    I +
Sbjct: 375 VNMSGRGDKDIFITSPIFR 393


>UniRef50_Q1V1Q0 Tryptophan synthase beta chain 1 n=6 Tax=root RepID=Q1V1Q0_PELUB
          Length = 410

 Score =  450 bits (1158), Expect = e-125,   Method: Composition-based stats.
 Identities = 158/396 (39%), Positives = 229/396 (57%), Gaps = 13/396 (3%)

Query: 6   NPYFG-EFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQN 64
           N ++G +FGG ++P+ L   +  L E F   + D +F  + +   KNY G PT+  K QN
Sbjct: 16  NGFWGGKFGGNFIPETLKKPIEDLTELFEKLRYDKKFLKERDYYFKNYIGSPTSFIKLQN 75

Query: 65  ITAGT-NTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALAS 123
           ++       +Y K     +GGAHK        L+AK+ GK  ++ +TGAG  G   ++A+
Sbjct: 76  LSDHLSGAQIYAKMVSEANGGAHKIYNATVHCLIAKKAGKKYVVGDTGAGYAGKMLSMAA 135

Query: 124 ALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYET 183
              GLKC+I+MGAKD++RQ PNV  M+  GAEV+PV+SGS TL DA +E +R W  + + 
Sbjct: 136 KKFGLKCKIFMGAKDIKRQKPNVDAMKKNGAEVVPVYSGSQTLVDAVSECMRYWVSNCDN 195

Query: 184 AHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAV--IACVGGGSNAIGMF 241
            H  +G+  GP+ +  I       I  E K QI     ++P  +  I CVGGGS+A G +
Sbjct: 196 THMCVGSTVGPNIFVKICGWSTAQISRELKVQIQSEFKKMPKKIKLINCVGGGSSAYGFW 255

Query: 242 ADFI--NETNVGLIGVEPGGHGIETGEHGAPLKHG-RVGIYFGMKAPMMQTEDGQIEESY 298
           ++FI  ++  + LIGVE GG    +  H APL +G ++GI  G  A + Q  +GQI ++ 
Sbjct: 256 SEFIDYDKKQIELIGVEAGG-PKNSKLHAAPLTNGAKLGILHGAAAYVCQNSEGQINDTA 314

Query: 299 SISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHA 358
           SISAGLD+P V P H +L  T RA Y S TD+ AL A+K +   E I P+LE SHA A A
Sbjct: 315 SISAGLDYPGVSPIHCFLKDTKRARYTSATDEAALNAYKLVTKLEKINPSLEPSHAFAEA 374

Query: 359 LKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKAR 394
           +K+  +  +K+ +++VN  G   KD     DILK R
Sbjct: 375 IKIAPKL-NKDTIIIVNSCGDAKKD----RDILKER 405


>UniRef50_A1DP73 Tryptophan synthase n=4 Tax=Trichocomaceae RepID=A1DP73_NEOFI
          Length = 460

 Score =  436 bits (1122), Expect = e-121,   Method: Composition-based stats.
 Identities = 147/374 (39%), Positives = 209/374 (55%), Gaps = 18/374 (4%)

Query: 8   YFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITA 67
            FG FGG + P+  M AL++L   F     D  F  +F   L +   RP+ L   +N+T 
Sbjct: 96  RFGTFGGCFAPESQMDALQELTLTFDRLISDYGFWKEF---LSSPGIRPSPLRFAENLTR 152

Query: 68  -GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALL 126
                 ++LKREDL   G+H    ++GQALLA+R+GK E++ E G+ +HG+  A     L
Sbjct: 153 IAGGANIWLKREDLNQHGSHNIRSIVGQALLARRLGKAEVVMECGSARHGIVCAATCTRL 212

Query: 127 GLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPV----HSGSATLKDACNEALRDWSGSYE 182
            +KC I MG++D   Q  +V  +R +GA V+       SG  TL+ A NEALR       
Sbjct: 213 NMKCTILMGSRDATDQKDSVDMIRKLGATVLTADMGASSGRGTLRAAVNEALRYSVAHLS 272

Query: 183 TAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREG-RLPDAVIACVGGGSNAIGMF 241
           T ++++    GPHP PTI R FQ ++GEE K Q     G RLPDA+++ VG GS A+GMF
Sbjct: 273 TTYHIMSGPIGPHPLPTITRTFQSILGEEIKTQFGGTSGDRLPDALVSPVGPGSAAVGMF 332

Query: 242 ADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSIS 301
             FI   +V L+G+E            APL HG +G+  G +  ++Q E GQI +S SIS
Sbjct: 333 YPFIEHPSVKLLGIEAA--------DAAPLSHGDIGVLHGCRTYLLQDEHGQILDSGSIS 384

Query: 302 AGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKM 361
             LDFPSVGP+ A+   T R +YV+ TD EAL     L   EGI+    + +A+   +++
Sbjct: 385 PDLDFPSVGPELAHWKETARVEYVTATDAEALRGVDILRSQEGIVSGAMTGYAVERTIRL 444

Query: 362 MRE-NPDKEQLLVV 374
            RE  P K+ +L+V
Sbjct: 445 ARELGPGKDVVLLV 458


>UniRef50_B6HPP8 Pc22g00910 protein n=1 Tax=Penicillium chrysogenum Wisconsin
           54-1255 RepID=B6HPP8_PENCW
          Length = 518

 Score =  431 bits (1108), Expect = e-119,   Method: Composition-based stats.
 Identities = 145/381 (38%), Positives = 226/381 (59%), Gaps = 19/381 (4%)

Query: 9   FGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITA- 67
           +G +GG + P+ +M  L +L   F +   DP F  ++    ++   R T L     +T+ 
Sbjct: 147 YGSYGGRFAPESIMGFLYELTSFFEATVSDPSFWEEYATFQRD---RVTPLHMAGKLTSL 203

Query: 68  GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLG 127
               T++LKRED    G+HKT  + GQ LLA+RMG++EI+ +  + +HG  +A   A LG
Sbjct: 204 AGGATIWLKREDKNEYGSHKTRNITGQLLLARRMGRSEIVTDCASAKHGKVTAAMCARLG 263

Query: 128 LKCRIYMGAKDVERQSPNVFRMRLMGAEVIPV--HSGSATLKDACNEALRDWSGSYETAH 185
           L+C + +GA D   Q  +V  M+ +GA+V+     SG   L+ A  EALR    ++E+A+
Sbjct: 264 LRCVVVIGADDASAQEKDVLEMKSLGAKVLTARAPSGMGGLRAAITEALRYAVCNHESAY 323

Query: 186 YMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFI 245
           Y++G+  GP P PT+ R FQ ++GEE  AQ+ E  GR PDA++  VG GS AIG+F  F+
Sbjct: 324 YLMGSPVGPSPLPTLARTFQSLLGEEVAAQMHEAAGRQPDALVTAVGSGSGAIGLFRPFL 383

Query: 246 NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLD 305
           +++++ L+GVE          + A L  G +G+  G +  ++Q  DGQI +S+SIS  ++
Sbjct: 384 HDSSIRLVGVEAA--------NAAALTDGGLGVLQGARTLLLQNHDGQILDSHSISPDMN 435

Query: 306 FPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRE- 364
             +VGP+ A+   +GR +  + TD  AL+ F+TL  HEGI+P L+SSHA++ AL + RE 
Sbjct: 436 LSTVGPEVAHWKDSGRIEISTATDAVALDGFRTLQQHEGILPGLDSSHAVSKALDLAREL 495

Query: 365 NPDKEQLLVV----NLSGRGD 381
            P K  +L+V    N+S RG 
Sbjct: 496 GPGKNVVLMVTGCDNISVRGL 516


>UniRef50_C8VGH6 Putative uncharacterized protein n=2 Tax=Emericella nidulans
           RepID=C8VGH6_EMENI
          Length = 443

 Score =  414 bits (1065), Expect = e-114,   Method: Composition-based stats.
 Identities = 135/385 (35%), Positives = 204/385 (52%), Gaps = 27/385 (7%)

Query: 7   PYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNIT 66
              G FGG + P++ M  L  L   F S   D  F  +F+    +   RP+ L    ++T
Sbjct: 73  ARLGRFGGQFAPELQMDLLLDLPSVFHSVLSDNRFWTEFS---ASPFLRPSPLHLAHSLT 129

Query: 67  AG-TNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASAL 125
                  ++LKR+DL   G+++T  ++GQ L A+ +GKTEI  E G   HG+  A   A 
Sbjct: 130 KAVGGANIWLKRDDLNPFGSYQTRNIVGQILFAQHIGKTEISMECGFAGHGLFCATMCAR 189

Query: 126 LGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS-----GSATLKDACNEALRDWSGS 180
           + +KC I MGA D+  Q   V  M+ +GA V+ V       GS TL+ A NEALR     
Sbjct: 190 MNMKCTILMGASDIAAQPDAVEEMKQLGATVVSVQCSISDDGSGTLRAATNEALRYSLTR 249

Query: 181 YETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGR-------LPDAVIACVGG 233
             + +++     GPHP PTI R FQ ++G+E K    E  GR        P A+++    
Sbjct: 250 LNSTYHISTGTVGPHPLPTITRTFQSLLGQEIKICSSELPGRGRRKNNFRPSALVST--S 307

Query: 234 GSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQ 293
           G+ A+GMFA FI++  V LI VE            APL HG  G+ +G K  ++Q E+GQ
Sbjct: 308 GAAALGMFAPFISDPAVRLIAVEAA--------DAAPLTHGSPGVMYGCKTLLLQDENGQ 359

Query: 294 IEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSH 353
           I  S+SIS  L+FP  GP+ A+    GR + V+ + +EA+   + LC  EGI+P L +SH
Sbjct: 360 ILPSHSISPDLNFPCAGPELAHWRDLGRLETVTASSEEAVRGLRILCESEGIVPGLATSH 419

Query: 354 ALAHALKMMRENPDKEQLLVVNLSG 378
           A+   +++ R+    + ++++ +SG
Sbjct: 420 AVLETVRVARQLGIGKDVVLL-ISG 443


>UniRef50_Q9WZ09 Tryptophan synthase beta chain 2 n=6 Tax=Bacteria RepID=TRPB2_THEMA
          Length = 422

 Score =  382 bits (982), Expect = e-105,   Method: Composition-based stats.
 Identities = 111/405 (27%), Positives = 163/405 (40%), Gaps = 51/405 (12%)

Query: 18  PQILMP-ALRQLEEAF-----VSAQKDPEFQAQFNDLLKNYA-GRPTALTKCQNITAGTN 70
           P+   P +  +L   F          +  F      +LK YA  RPT L +   +     
Sbjct: 33  PETKQPISPEKLSVIFPMSLIEQEVSEERFIEIPEPVLKEYAVYRPTPLIRATFLEEYLQ 92

Query: 71  --TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGL 128
               +Y K E +   G+HK N  + QA   K  G   ++ ETGAGQ G A + A A  GL
Sbjct: 93  TPARIYYKYEGVSPTGSHKPNTAIAQAYYNKIEGVKRLVTETGAGQWGSALSYAGAKFGL 152

Query: 129 KCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS---------------GSATLKDACNEA 173
           + +++M     +++    + M L G +V P  S                  +L  A +EA
Sbjct: 153 EVKVFMVKVSYQQKPMRKYMMNLFGGKVTPSPSEETNFGRKILSEDPDNPGSLGIAISEA 212

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
           L + + S     Y LG+          V   Q +IG E K Q+ E  G  PD ++ C GG
Sbjct: 213 L-EVAVSDPNTKYSLGSVL------NHVLLHQTVIGLEIKKQL-ELIGEKPDILLGCHGG 264

Query: 234 GSNAIGMFADFINET----NVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPM--- 286
           GSN  G    F+ +     ++  +  EP             L  G     FG  A +   
Sbjct: 265 GSNFGGTILPFVPDKLSGRDIRFVACEPAA--------CPSLTKGNYDYDFGDTAGLTPL 316

Query: 287 --MQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEG 344
             M T           + GL +    P  A L   G  +  +   DE  EA K     EG
Sbjct: 317 LKMYTLGKDFIPPKIHAGGLRYHGSAPIIARLVKEGLVEAQAFDQDETFEAAKIFAKLEG 376

Query: 345 IIPALESSHALAHALKMMRENP--DKEQLLVVNLSGRGDKDIFTV 387
           IIPA ES+HA+A A++  ++     KE+++V  LSG G  D+   
Sbjct: 377 IIPAPESAHAIAGAIREAKKAKEEGKERVIVFTLSGHGLLDLTAY 421


>UniRef50_D2L2T8 Pyridoxal-phosphate dependent TrpB-like enzyme n=2 Tax=Bacteria
           RepID=D2L2T8_9DELT
          Length = 447

 Score =  377 bits (968), Expect = e-103,   Method: Composition-based stats.
 Identities = 102/412 (24%), Positives = 164/412 (39%), Gaps = 54/412 (13%)

Query: 18  PQILMP-ALRQLEEAFVSAQKDPEFQAQ--------FNDLLKNYAGRPTALTKCQNITAG 68
           PQ   P +  QLE  F  A  + E   +          D+ + Y  RPT L + + +   
Sbjct: 33  PQTKQPVSPEQLEAIFPKAVIEQELSTERWLPIPEPVRDIYRLY--RPTPLVRAKRLEEA 90

Query: 69  TN--TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALL 126
                 ++ K E +   G+HK N  + QA   K  G   I  ETGAGQ G A + A ++ 
Sbjct: 91  LGVKCKIFYKNESVSPAGSHKPNTAIPQAYYNKLEGVRRISTETGAGQWGTALSFACSMF 150

Query: 127 GLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSG---------------SATLKDACN 171
           G+ C +YM      ++      +   G E+    S                S +L  A +
Sbjct: 151 GMACTVYMVKVSYNQKPYRRILINAYGGEIFASPSENTKTGRAVLASDPDCSGSLGLAIS 210

Query: 172 EALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACV 231
           EA+ D + ++    Y LG+          V   Q +IG E + Q+    G  PD ++ CV
Sbjct: 211 EAVED-AATHADTKYALGSVL------NHVLHHQTIIGLEVEKQL-AAIGEKPDYLVGCV 262

Query: 232 GGGSNAIGMFADFINE----TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPM- 286
           GGGSN  G+   F+        +  I VEP        +    L  G+    +G  A + 
Sbjct: 263 GGGSNFAGLVLPFLPRKLSGEAIRFIAVEP--------KACPTLTRGQFRYDYGDVAQLT 314

Query: 287 ----MQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLH 342
               M T       +   + GL +    P    L + G  D  +    E  +A +     
Sbjct: 315 PLLKMHTLGHAFMPAPIHAGGLRYHGGAPIVCNLANEGLIDATAYFQTECFDAARLFLRT 374

Query: 343 EGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKAR 394
           EG +PA E+SHA+  A++  ++    E ++ +  SG G  D+ +    L+ +
Sbjct: 375 EGFLPAPETSHAIKGAIETAKKAKPGENVVFL-YSGHGLLDLASYDAFLQGK 425


>UniRef50_B6YSU5 Tryptophan synthase beta chain n=232 Tax=cellular organisms
           RepID=TRPB_THEON
          Length = 443

 Score =  376 bits (965), Expect = e-102,   Method: Composition-based stats.
 Identities = 118/427 (27%), Positives = 173/427 (40%), Gaps = 65/427 (15%)

Query: 17  VPQILMPALR------------------QLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTA 58
           +P+ L P L                   +L +  +S ++  +   +  +L     GRPT 
Sbjct: 21  LPEPLAPPLDPETDEPMESEKLLRIFASELVKQEMSMERYIDIPKKVRELYAK-IGRPTP 79

Query: 59  LTKCQNITAGT--NTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           L +  N+         +Y K E     G+HK N  L QA  AK+ G   ++ ETGAGQ G
Sbjct: 80  LFRATNLEKALETPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETGAGQWG 139

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGS------------- 163
            A +LA AL+G+  R+YM      ++      MRL GAE+ P  S               
Sbjct: 140 TALSLAGALMGINVRVYMARASFYQKPYRKTIMRLYGAEIYPSPSDRTEIGRKFLSEDPN 199

Query: 164 --ATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREG 221
               L  A +EA+ D     E A Y LG+          V   Q +IG E K Q+ E   
Sbjct: 200 HPGGLGIAISEAIED-VLRDEKARYALGSVL------NHVLMHQTVIGLEAKEQMKEF-- 250

Query: 222 RLPDAVIACVGGGSNAIGMFADFINET-----NVGLIGVEPGGHGIETGEHGAPLKHGRV 276
             PD +I CVGGGSN  G+   F+ +      +   I VEP             +  G  
Sbjct: 251 EDPDVIIGCVGGGSNFAGLAYPFVKDRLDGKADYEFIAVEPRA--------APSMTRGVY 302

Query: 277 GIYFGMKAPM-----MQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDE 331
              +G    +     M T           + GL +  + P  + L + G    V+    E
Sbjct: 303 TYDYGDSGGLTPKMKMHTLGHTYYVPPIHAGGLRYHGLAPTLSILINHGIVRPVAYHQTE 362

Query: 332 ALEAFKTLCLHEGIIPALESSHALAHALKMMRENP--DKEQLLVVNLSGRGDKDIFTVHD 389
             EA +     EGI+PA ES+HA+  A+    +     KE++++ NLSG G  D+    D
Sbjct: 363 VFEAARLFAKTEGIVPAPESAHAVKAAIDRALKAKEEGKEEVILFNLSGHGLLDLKGYED 422

Query: 390 ILKARGE 396
            L  + E
Sbjct: 423 FLDGKLE 429


>UniRef50_A8F8F7 Tryptophan synthase beta chain n=12 Tax=cellular organisms
           RepID=TRPB_THELT
          Length = 422

 Score =  365 bits (938), Expect = 1e-99,   Method: Composition-based stats.
 Identities = 105/369 (28%), Positives = 153/369 (41%), Gaps = 45/369 (12%)

Query: 48  LLKNYA-GRPTALTKCQNITAGTN--TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKT 104
           +L+ YA  RPT L +   +         +Y K E     G+HKTN  L QA   K  G  
Sbjct: 69  VLEEYAVFRPTPLFRATYLEEFLQTPARIYYKYEGASPTGSHKTNTALAQAYYNKISGTE 128

Query: 105 EIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS--- 161
            ++ ETGAGQ G A   + A  GLK  ++M     E++    + MRL   +V+P  S   
Sbjct: 129 RLVTETGAGQWGSALCYSGAKFGLKVNVFMVKISYEQKPMRKYLMRLFDGDVVPSPSEKT 188

Query: 162 ------------GSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIG 209
                          +L  A +EA+ + + S     Y LG+          V   Q +IG
Sbjct: 189 SFGKSILASNSENPGSLGIAISEAI-EITLSDSRTKYSLGSVL------NHVLLHQTVIG 241

Query: 210 EETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINE----TNVGLIGVEPGGHGIETG 265
            E K Q+ E  G  PD ++ C GGGSN  G    FI +      +  +  EP        
Sbjct: 242 LELKKQL-EVLGEKPDVILGCHGGGSNFGGTVLPFIPDKLSGKEIKFVACEPTA------ 294

Query: 266 EHGAPLKHGRVGIYFGM---KAPM--MQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTG 320
                L  GR    +G      P+  M T           + GL +    P  + L   G
Sbjct: 295 --CPSLTRGRYDYDYGDTAGMTPLLKMYTLGKDFIPPKIHAGGLRYHGAAPIISRLVKEG 352

Query: 321 RADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKE--QLLVVNLSG 378
             + V+   DE   A K     EGI+PA ESS+A+A A++  ++  +    +++V NLSG
Sbjct: 353 LIEAVAFDQDEIFSAAKLFAKLEGIVPAPESSYAIAGAIREAKKAKEHNIPRVVVFNLSG 412

Query: 379 RGDKDIFTV 387
            G  D+   
Sbjct: 413 HGLFDLTAY 421


>UniRef50_Q13AA2 Tryptophan synthase, beta chain-like n=7 Tax=Bacteria
           RepID=Q13AA2_RHOPS
          Length = 454

 Score =  356 bits (915), Expect = 6e-97,   Method: Composition-based stats.
 Identities = 99/405 (24%), Positives = 160/405 (39%), Gaps = 49/405 (12%)

Query: 19  QILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTN--TTLYLK 76
           + L P    L+E  V+  +  +  A   D+ + +  RP+ L + + +         +Y K
Sbjct: 47  EPLFPMELILQE--VATDRYIDIPAPVRDVFRMW--RPSPLVRARRLEQALGTPAKIYYK 102

Query: 77  REDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGA 136
            E +   G+HK N  + QA   K+ G  ++  ETGAGQ G + A A +L GL   ++   
Sbjct: 103 YEGVSPAGSHKPNTAVPQAWYNKQAGIKKLSTETGAGQWGSSLAFAGSLFGLDVLVFQVR 162

Query: 137 KDVERQSPNVFRMRLMGAEVIPVHSG---------------SATLKDACNEALRDWSGSY 181
              +++      M   GA  I   S                  +L  A +EA+ + +   
Sbjct: 163 ISYDQKPYRRALMETYGARCIASPSNETESGRSILAQTPDSPGSLGIAISEAV-EVAAKN 221

Query: 182 ETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMF 241
               Y LG+          V   Q +IGEE   Q  E  G  PD +I C GGGSN  G+ 
Sbjct: 222 PDIKYALGSVL------NHVMLHQTIIGEEAIKQC-EMAGDDPDVIIGCAGGGSNFAGLA 274

Query: 242 ADFIN-----ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPM-----MQTED 291
             FI           +I VEP             L  G+    FG  + +     M T  
Sbjct: 275 FPFIGLQLRGGRRRRIIAVEPAA--------CPSLTRGKYAYDFGDTSHLTPLMKMHTLG 326

Query: 292 GQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALES 351
                    + GL +  +G   ++    G  +  +    +  EA      +EGI+PA ES
Sbjct: 327 STFMPPGFHAGGLRYHGMGAMVSHAYELGLIEARAYHQVKCFEAGVQFARNEGIVPAPES 386

Query: 352 SHALAHALKMMR--ENPDKEQLLVVNLSGRGDKDIFTVHDILKAR 394
           +HA+  A+      +   K + ++ NLSG G  D+ +  +  + +
Sbjct: 387 THAVRCAIDEALRCKEEGKSETILFNLSGHGHFDMQSYINYFEGK 431


>UniRef50_C7GZ56 Tryptophan synthase beta chain 2 n=3 Tax=Bacteria
           RepID=C7GZ56_9FIRM
          Length = 461

 Score =  343 bits (880), Expect = 7e-93,   Method: Composition-based stats.
 Identities = 101/398 (25%), Positives = 151/398 (37%), Gaps = 49/398 (12%)

Query: 29  EEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGT--NTTLYLKREDLLHGGAH 86
           ++         +   +  DL + Y  RP+ L +  ++         +Y K E     G+H
Sbjct: 60  KQELNDTDTYIDIPEKLMDLYRQY--RPSPLCRAYHLEKALDTPAKIYYKFEGNNTAGSH 117

Query: 87  KTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNV 146
           K N  + Q   AK  G   +  ETGAGQ G A A A    GL   +YM     E +    
Sbjct: 118 KLNSSIPQVYYAKEQGLKGVTTETGAGQWGTALAEACGFFGLDLIVYMVRVSYEGKPFRR 177

Query: 147 FRMRLMGAEVIPVHS---------------GSATLKDACNEALRDWSGSYETAHYMLGTA 191
             +   G +VIP  S                  +L  A +EA+ + +       Y LG+ 
Sbjct: 178 NIIETFGGKVIPSPSDTTESGRAILKMDPDSPGSLGTAISEAV-ETASKDPGFRYTLGSV 236

Query: 192 AGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINET--- 248
                    V   Q +IG E+    ++     PD VI C GGGSN  G+ A F  +    
Sbjct: 237 L------NQVALHQSIIGMESYK-AMQIYDEYPDIVIGCAGGGSNLAGLIAPFARDKIQG 289

Query: 249 --NVGLIGVEPGGHGIETGEHGAPLKHGRVGIYF---GMKAPM--MQTEDGQIEESYSIS 301
             N  L+ VEP             L  G     +   G   PM  M T   +     + +
Sbjct: 290 EHNPELLAVEPS--------SCPTLTRGSYLYDYCDAGKITPMAKMYTLGNEFMPPATHA 341

Query: 302 AGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKM 361
            GL +  + P  + L   G     S    E  EA K    +E I+PA ESSHA+  A+  
Sbjct: 342 GGLRYHGMSPIVSKLYHDGYMKAKSYGQTEIFEAAKFFAKYETILPAPESSHAIKGAIDE 401

Query: 362 MREN--PDKEQLLVVNLSGRGDKDIFTVHDILKARGEI 397
             +    + ++ ++  L+G G  D+         RGE+
Sbjct: 402 AIKCREENTKKTILFGLTGTGFFDMKAYDQF--NRGEM 437


>UniRef50_C7N0P7 Pyridoxal-phosphate dependent TrpB-like enzyme n=8 Tax=Bacteria
           RepID=C7N0P7_SLAHD
          Length = 470

 Score =  341 bits (876), Expect = 2e-92,   Method: Composition-based stats.
 Identities = 108/382 (28%), Positives = 155/382 (40%), Gaps = 48/382 (12%)

Query: 40  EFQAQFNDLLKNYAGRPTALTKCQNITAGTN--TTLYLKREDLLHGGAHKTNQVLGQALL 97
           +      ++ K Y  RP+ L +  N+         +Y K E     G+HK N  L QA  
Sbjct: 69  DIPEGIREMYKVY--RPSPLCRAYNLEKALGTPAKIYYKFEGNNTSGSHKLNSALAQAYY 126

Query: 98  AKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVI 157
           A   G T I  ETGAGQ G A + A+A  GL C ++M     E++      M+  GA+V 
Sbjct: 127 AHEQGLTTITTETGAGQWGTALSEAAAHYGLNCDVFMVRASYEQKPFRRSVMQTFGAQVT 186

Query: 158 PVHSG---------------SATLKDACNEALRDWSGSYET-AHYMLGTAAGPHPYPTIV 201
           P  S                S +L  A +EA+       E    Y LG+          V
Sbjct: 187 PSPSQETEIGRKMYADEANRSGSLGTAISEAVERALHVPENKGRYQLGSVL------NQV 240

Query: 202 REFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINE------TNVGLIGV 255
              Q +IG E+ A   E  G  PD VI C GGGSN  G+ A F+ +       +   I V
Sbjct: 241 VLHQSIIGLESLAAFDEL-GEYPDVVIGCAGGGSNLGGLIAPFMRDKLTGEKPDTRFIAV 299

Query: 256 EPGGHGIETGEHGAPLKHGRVGIYF---GMKAPM--MQTEDGQIEESYSISAGLDFPSVG 310
           EP             L  GR    F   G   P+  M T       S   + GL +  + 
Sbjct: 300 EPA--------SCPSLTRGRYAYDFADTGQTCPLVKMYTLGNGFIPSPDHAGGLRYHGMS 351

Query: 311 PQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENP--DK 368
           P  + L   G  D VS+   +   A +     E I+PA ES+HA+  A++  R+     +
Sbjct: 352 PIISKLKHDGYLDAVSVKQTDVFAAAEEFAKLETILPAPESAHAICVAMEEARKCAETGE 411

Query: 369 EQLLVVNLSGRGDKDIFTVHDI 390
           E++++  L+G G  D+      
Sbjct: 412 EKVILFGLTGTGYFDMTAYEAF 433


>UniRef50_Q9Y8T5 Tryptophan synthase beta chain 1 n=10 Tax=Thermoprotei
           RepID=TRPB1_AERPE
          Length = 427

 Score =  340 bits (872), Expect = 5e-92,   Method: Composition-based stats.
 Identities = 120/397 (30%), Positives = 171/397 (43%), Gaps = 34/397 (8%)

Query: 20  ILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTT----LYL 75
           IL   L + E         P    +    L    GRPT L + + +           +Y 
Sbjct: 40  ILPSRLIEDEYILARWVDIPG---EVRKALAR-IGRPTPLIRAEGLEKVLGVKGRVRIYY 95

Query: 76  KREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMG 135
           K E +L  G+HK N  + QA  AK  G  EI+ ETGAGQ G+A++ A+AL+GLK  ++M 
Sbjct: 96  KSEAVLPTGSHKINTAIAQAYYAKLDGAKEIVTETGAGQWGLAASTAAALMGLKATVFMT 155

Query: 136 AKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSY---------ETAHY 186
           A   + +      M   GA VI   S    L D   EAL ++  ++         E   Y
Sbjct: 156 ASSFKSKIQRRLLMEAQGARVISSPS---KLTDTGREALEEYGSTHPGSLGLAIAEAVEY 212

Query: 187 MLGTA---AGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFAD 243
            L +      P      V   Q +IG E   Q+ E     PD V+ACVGGGSN  G    
Sbjct: 213 TLESGDRRYLPGSVLEAVLMHQTVIGLEALDQLPEE----PDVVVACVGGGSNFGGFTYP 268

Query: 244 FINETNVGLIGVEPGGHGIETGEHGAPLKHGRV---GIYFGMKAPM--MQTEDGQIEESY 298
            I    +   G E              L  G     G+   +  P+  M T   +     
Sbjct: 269 MIG-ARLRGEGFEKTRFIAAESTAAPKLTRGEYRYDGLDSSLILPLAKMYTLGHRYTPPP 327

Query: 299 SISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHA 358
           S +AGL +  V P  + L   G  +  +I  +EAL +   +   EG++PA ESSHA+A A
Sbjct: 328 SHAAGLRYHGVSPSLSILRRLGLVEAEAIPQEEALASILLMARSEGVVPAPESSHAVALA 387

Query: 359 LKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKARG 395
            ++ R+ PD   ++  NLSG G  D+  +   L+ RG
Sbjct: 388 ARIARKLPDGS-VVAFNLSGHGLLDLDALQKALEIRG 423


>UniRef50_Q970N1 Tryptophan synthase beta chain 2 n=16 Tax=Archaea RepID=TRPB2_SULTO
          Length = 431

 Score =  339 bits (870), Expect = 1e-91,   Method: Composition-based stats.
 Identities = 102/401 (25%), Positives = 162/401 (40%), Gaps = 37/401 (9%)

Query: 19  QILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNY--AGRPTALTKCQNITAGTN--TTLY 74
           Q+L   + +LE +     K PE      ++L+ Y   GRPT + + + +         +Y
Sbjct: 45  QVLPSKVLELEFSKERYIKIPE------EVLQRYLQVGRPTPIIRARKLEEYLGGYIKIY 98

Query: 75  LKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYM 134
           +K E   + G+HK N  L     AK      +  ETGAGQ G A ALASAL  ++  I+M
Sbjct: 99  MKMESHTYTGSHKINSALAHVYFAKLDNAKFVSTETGAGQWGSAVALASALFNIQAHIFM 158

Query: 135 GAKDVERQSPNVFRMRLMGAEVIPVHS-----GSATLKDACNEALRDWSGSYETAHYMLG 189
                  +    + M++  A+V P  S     G   L    N          E  +Y L 
Sbjct: 159 VRTSYYAKPYRRYLMQMYNAQVHPSPSEFTRYGREVLAKDPNTPGSLGIAISEAVYYALE 218

Query: 190 TAAGPHPYPTIVR---EFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFIN 246
              G +   ++V     F+ + G E K Q+ E  G  PD +I  VGGGSN   +   F+ 
Sbjct: 219 N-GGKYVVGSVVNSDILFKTIAGMEAKKQM-EMIGEDPDYIIGVVGGGSNYAALAYPFLG 276

Query: 247 ET----NVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPM-----MQTEDGQIEES 297
           E      V    +  G   +        +  G     +   A +     M T       +
Sbjct: 277 EELRKGKVRRKYIASGAIEV------PKMTKGVYKYDYPDTAKILPMLKMYTIGSDFIPA 330

Query: 298 YSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAH 357
              + GL + +V P  + L   G       + +EA    K     EG +PA E+SHAL  
Sbjct: 331 PVYAGGLRYHAVAPTLSLLMYKGIVQARDYSQEEAFSWAKLFSQIEGWVPAPETSHALPI 390

Query: 358 ALKMMRENP--DKEQLLVVNLSGRGDKDIFTVHDILKARGE 396
             +++ E     +++ ++++ SG G  D+    D+L    E
Sbjct: 391 LKEIVEEAKKSGEKKTVLISFSGHGLLDLANYADVLGFNKE 431


>UniRef50_C7DG26 Pyridoxal-phosphate dependent TrpB-like enzyme n=1 Tax=Candidatus
           Micrarchaeum acidiphilum ARMAN-2 RepID=C7DG26_9EURY
          Length = 446

 Score =  337 bits (865), Expect = 4e-91,   Method: Composition-based stats.
 Identities = 98/395 (24%), Positives = 158/395 (40%), Gaps = 39/395 (9%)

Query: 20  ILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTN--TTLYLKR 77
           +L   + +LE +       PE   +  D  K    RPT + + + + A       +Y+K 
Sbjct: 56  VLPKGVLELEFSDKDHIPIPE---EIRDKFKM-VNRPTPIIRARQLEAHFGNKVKIYMKM 111

Query: 78  EDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAK 137
           E   + G+HK N  + QA  AK  G   +  ETGAGQ G A ALA++L GL+ +I+M   
Sbjct: 112 EGFTYVGSHKINSSIPQAYYAKADGAKFVTTETGAGQWGSAVALAASLFGLESKIFMVKV 171

Query: 138 DVERQSPNVFRMRLMGAEVIPVHS---------------GSATLKDACNEALRDWSGSYE 182
               +    + M + G EV P  S                  +L  A  +A+        
Sbjct: 172 SYAGKPYRRYLMNMFGGEVHPSPSELTGFGRGILRKEPDSPGSLGMAITDAVEY--AKEH 229

Query: 183 TAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFA 242
              Y++G+             F+ + G E K Q+ E  G  PD VI CVGGGSN  G+  
Sbjct: 230 GGKYVVGSVVNSD------LMFKSIAGLEAKKQM-ESIGEDPDYVIGCVGGGSNYAGLAY 282

Query: 243 DFINET-NVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPM-----MQTEDGQIEE 296
            F+ E    G I       G         +  G+    +     +     M T       
Sbjct: 283 PFLEEELKAGKIRRRYIAAG---SAEIPKMTKGKYEYDYPDTGKVLPQLKMYTVGHDFVP 339

Query: 297 SYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALA 356
               + GL + +V P  + L S G  +      +E+    K     EG +PA E+SH+  
Sbjct: 340 PPIYAGGLRYHAVAPSLSLLMSKGIVEARDYDQNESFRYAKLYSKIEGYVPAPETSHSFP 399

Query: 357 HALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDIL 391
              ++ ++   K+ +++++ SG G  D+    +  
Sbjct: 400 IIEEIAKKAGSKKPVVLMSFSGNGMLDLANYAEAF 434


>UniRef50_B1KQQ7 Pyridoxal-5'-phosphate-dependent protein beta subunit n=2
           Tax=Proteobacteria RepID=B1KQQ7_SHEWM
          Length = 440

 Score =  334 bits (856), Expect = 4e-90,   Method: Composition-based stats.
 Identities = 100/363 (27%), Positives = 161/363 (44%), Gaps = 35/363 (9%)

Query: 53  AGRPTALTKCQNITAGTN--TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAET 110
            GRPT L +  ++         +Y KRED +  G+ K +  + QA  AK+ G+  +I+ET
Sbjct: 87  CGRPTPLRRALSLEKHLKTPARIYFKREDTMATGSFKLSTAVAQAYYAKQEGREILISET 146

Query: 111 GAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS--------- 161
           GAGQ G++ AL S + GL  RI+M    +E++      M+++G EV P  S         
Sbjct: 147 GAGQWGMSVALVSQMFGLDARIFMARCSLEQKPYRQHYMKMLGCEVYPSPSTKTECGKEL 206

Query: 162 ------GSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQ 215
                    ++  A +EA+       E A    G+A         V   Q ++G E K Q
Sbjct: 207 LLQTPGHPGSIGSAISEAI-------ENALDTPGSAYLSGSNVNHVHLHQTLLGLEVKQQ 259

Query: 216 ILEREGRLPDAVIACVGGGSNAIGMFADFINETNVG----LIGVEPGGHGIETGEHGAPL 271
           +        D ++ACV GGSN  G    F+ E N G    ++GVE       T       
Sbjct: 260 LSMAGESNVDHLVACVSGGSNLCGFMMPFLPEKNSGAKIDMLGVESTASPRLT---QGTY 316

Query: 272 KHGRVGIYFGMKAPMMQTEDGQ-IEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDD 330
           ++ R  +  G    ++    G+    +     GL   +  P  + L   G     ++ + 
Sbjct: 317 EYCRSDVA-GYTPEVLSHSMGESYIPAPVHVGGLRNHNSSPLVSLLCREGILRAEALDEF 375

Query: 331 EALEAFKTLCLHEGIIPALESSHALAHALKMMREN--PDKEQLLVVNLSGRGDKDIFTVH 388
            A +A + +   EGI+ A ESSHA+A A+ +  +    +KE ++V   SG G  D+   +
Sbjct: 376 NAFKAGQIMLKTEGILVAPESSHAVAAAIDLAEKARIENKESVIVFLASGNGFLDLQGYN 435

Query: 389 DIL 391
           D+L
Sbjct: 436 DVL 438


>UniRef50_A8M857 Pyridoxal-5'-phosphate-dependent protein beta subunit n=3
           Tax=Actinomycetales RepID=A8M857_SALAI
          Length = 447

 Score =  304 bits (778), Expect = 4e-81,   Method: Composition-based stats.
 Identities = 104/381 (27%), Positives = 155/381 (40%), Gaps = 36/381 (9%)

Query: 37  KDPEFQA---QFNDLLKNYAGRPTALTKCQNITAGTNTT--LYLKREDLLHGGAHKTNQV 91
           ++ E+        D  ++Y  RPT L +             +++K E     G+HK    
Sbjct: 49  RNDEYWEIPLPVLDAYRSY--RPTPLWRATRFETAVGAKVPIWVKYEGGNISGSHKLTTA 106

Query: 92  LGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRL 151
           L QA   +  G  E++  TGAGQ G A A A AL GL+C ++M    + R+      M++
Sbjct: 107 LAQAYYYRNAGARELVTGTGAGQWGTALAAACALFGLRCTVFMVGSSLSRKPYRGVLMKM 166

Query: 152 MGAEVIPVHSGSA-----------TLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTI 200
           +GAEV    SG+            +L  A  EA+   +G  + A + +G+        T 
Sbjct: 167 LGAEVQASPSGTTRVSRSAQGQGNSLSLAIGEAVEYAAGR-DGAAFCIGSG------ETY 219

Query: 201 VREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGH 260
               Q +IG E   Q+ E+ G + DAV+ CVG GSN  G+   F  E      G      
Sbjct: 220 SILHQSVIGIEAGEQLQEQGGEV-DAVVGCVGAGSNFGGVALPFHAEARSQ--GTNAPLL 276

Query: 261 GIETGEHGAPLKHGRVGI---YFGMKAPM--MQTEDGQIEESYSISAGLDFPSVGPQHAY 315
                     L  G            +P+  M T         S SAGL F       + 
Sbjct: 277 VAAESSSAPKLTQGIYAYDRTDSTDTSPLEAMYTIGSSYSIPDSHSAGLRFHGAAKLVSA 336

Query: 316 LNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQL---L 372
           L  +G    ++I    ALEA +     E ++PA ES HALA A ++     D  Q    +
Sbjct: 337 LRHSGHVAAMAIDQVVALEAGQRFATTEMVVPAPESGHALAAAAQLATTGADDLQASHGV 396

Query: 373 VVNLSGRGDKDIFTVHDILKA 393
           +V +SG G  D+     +L  
Sbjct: 397 LVCVSGHGYLDLSAYQQLLDG 417


>UniRef50_D1NGU1 DNA (Cytosine-5-)-methyltransferase (Fragment) n=3 Tax=Haemophilus
           influenzae HK1212 RepID=D1NGU1_HAEIN
          Length = 256

 Score =  285 bits (730), Expect = 2e-75,   Method: Composition-based stats.
 Identities = 136/167 (81%), Positives = 148/167 (88%)

Query: 38  DPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALL 97
           DP FQA+F DLLKNYAGRPTALT C N+T GT   +YLKREDLLHGGAHKTNQVLGQ LL
Sbjct: 1   DPTFQAEFADLLKNYAGRPTALTLCHNLTKGTKAKIYLKREDLLHGGAHKTNQVLGQILL 60

Query: 98  AKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVI 157
           AKRMGKT IIAETGAGQHGVA+ALA A+L + CRIYMGAKDV+RQSPNVFRMRLMGAEVI
Sbjct: 61  AKRMGKTRIIAETGAGQHGVATALACAMLDMPCRIYMGAKDVDRQSPNVFRMRLMGAEVI 120

Query: 158 PVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREF 204
           PV  GS +LKDAC EA+RDWS +YET HY+LGTAAGPHP+PTIVREF
Sbjct: 121 PVQKGSCSLKDACCEAMRDWSANYETTHYLLGTAAGPHPFPTIVREF 167


>UniRef50_Q56YC7 Tryptophan synthase beta chain 1 n=3 Tax=cellular organisms
           RepID=Q56YC7_ARATH
          Length = 141

 Score =  205 bits (522), Expect = 2e-51,   Method: Composition-based stats.
 Identities = 73/141 (51%), Positives = 99/141 (70%), Gaps = 1/141 (0%)

Query: 252 LIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGP 311
           +IGVE  G G+++G+H A L  G VG+  G  + ++Q +DGQI E +SISAGLD+P VGP
Sbjct: 1   MIGVEAAGFGLDSGKHAATLTKGDVGVLHGAMSYLLQDDDGQIIEPHSISAGLDYPGVGP 60

Query: 312 QHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQL 371
           +H++    GRA+Y SITD+EALEAFK +   EGIIPALE+SHALA+  K+     D  ++
Sbjct: 61  EHSFFKDMGRAEYYSITDEEALEAFKRVSRLEGIIPALETSHALAYLEKLCPTLSDGTRV 120

Query: 372 LVVNLSGRGDKDIFTVHDILK 392
           ++ N SGRGDKD+ TV   L 
Sbjct: 121 VL-NFSGRGDKDVQTVAKYLD 140


>UniRef50_D1C1V4 Threonine synthase n=3 Tax=Bacteria RepID=D1C1V4_SPHTD
          Length = 415

 Score =  162 bits (409), Expect = 3e-38,   Method: Composition-based stats.
 Identities = 85/348 (24%), Positives = 135/348 (38%), Gaps = 57/348 (16%)

Query: 57  TALTKCQNITAGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           T L     +        L +K +     G+ K   +      AK +G + + A   AG  
Sbjct: 81  TPLLPASRLGKALGYNRLLVKDDGQNPTGSFKARGLCAAVSRAKELGASAV-AIPSAGNA 139

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
             A +  +A  GL   ++M A   E   P     R  GA V  V      L + C   +R
Sbjct: 140 AAAMSAYAARAGLDAYVFMPADTPE---PMKAECRAYGARVFLVI----GLINDCGRVVR 192

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
             +G+     + + T   P+       E ++ +G E   Q+     RLPDA++   GGG+
Sbjct: 193 --AGAEARGWFDVSTLKEPYR-----AEGKKTMGLELAEQL---GWRLPDAIVYPTGGGT 242

Query: 236 NAIGMFADFINETNVGLIGVE-------------PGGHGIETGEHGAPLKHGRVGIYFGM 282
             +GM+  F     +GLIG E             P     E GE  A L  G   +  G+
Sbjct: 243 GIVGMWKAFDELEQLGLIGSERPRMIVVQSEGCAPIVRAFEQGERHAQLWEGAATVAPGI 302

Query: 283 KAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLH 342
           + P+   +       Y I   LD        A   S G    ++++D+E LE  +    H
Sbjct: 303 RVPVAIGD-------YLI---LD--------AVRQSGG--TAITVSDEELLEGMRLAATH 342

Query: 343 EGIIPALESSHALAHALKMMRE----NPDKEQLLVVNLSGRGDKDIFT 386
           EG+  + E+   +A A +++RE      D E +L    +G    D+ T
Sbjct: 343 EGLFVSPEAGAVVAAA-RLLRERGVLGQDDEVVLFATGAGLKHTDLVT 389


>UniRef50_C6TEW3 Putative uncharacterized protein (Fragment) n=1 Tax=Glycine max
           RepID=C6TEW3_SOYBN
          Length = 238

 Score =  159 bits (402), Expect = 2e-37,   Method: Composition-based stats.
 Identities = 40/147 (27%), Positives = 67/147 (45%), Gaps = 5/147 (3%)

Query: 18  PQILMPAL-RQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITA--GTNTTLY 74
           P  L P    +L    +++ +  +   +  D+ K +  RPT L + + +     T   +Y
Sbjct: 91  PDDLSPLFPDELIRQEIASDRFIDIPDEVLDVYKLW--RPTPLIRAKRLEKLLDTPARIY 148

Query: 75  LKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYM 134
            K E +   G+HK N  + QA    + G   ++ ETGAGQ G A A A ++ GL C ++ 
Sbjct: 149 YKYEGVSPAGSHKPNSAVPQAWYNLQAGVKNVVTETGAGQWGSALAFACSIFGLGCEVWQ 208

Query: 135 GAKDVERQSPNVFRMRLMGAEVIPVHS 161
                + +      M+  GA+V P  S
Sbjct: 209 VRASYDSKPYRRLMMQTWGAKVHPSPS 235


>UniRef50_A8HUC1 Tryptophan synthase beta subunit (Fragment) n=1 Tax=Bacillus
           subtilis subsp. subtilis RepID=A8HUC1_BACSU
          Length = 126

 Score =  134 bits (337), Expect = 6e-30,   Method: Composition-based stats.
 Identities = 44/87 (50%), Positives = 57/87 (65%), Gaps = 1/87 (1%)

Query: 20  ILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTN-TTLYLKRE 78
            LM  L +++ AF   + DP F+ ++  LLK+Y+GRPTALT    +T       +YLKRE
Sbjct: 1   TLMQPLDEIQTAFKQIKDDPAFREEYYKLLKDYSGRPTALTYADRVTEYLGGAKIYLKRE 60

Query: 79  DLLHGGAHKTNQVLGQALLAKRMGKTE 105
           DL H G+HK N  LGQALLAK+MGKT 
Sbjct: 61  DLNHTGSHKINNALGQALLAKKMGKTR 87


>UniRef50_C1SGJ4 Tryptophan synthase beta chain n=1 Tax=Denitrovibrio acetiphilus
          DSM 12809 RepID=C1SGJ4_9BACT
          Length = 106

 Score =  133 bits (334), Expect = 1e-29,   Method: Composition-based stats.
 Identities = 36/83 (43%), Positives = 52/83 (62%)

Query: 8  YFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITA 67
          ++G +GG +VP+ L+PA+  LE  F   + D +F  +  +L   YAGRPT + K QN++ 
Sbjct: 6  FYGRYGGQFVPETLIPAIDDLEAKFEELKDDAKFNEELKELFTKYAGRPTPVYKAQNLSD 65

Query: 68 GTNTTLYLKREDLLHGGAHKTNQ 90
               +YLKREDL+H GAHK N 
Sbjct: 66 KYGCEIYLKREDLMHTGAHKLNN 88


>UniRef50_B9SZR5 Tryptophan synthase beta chain, putative n=1 Tax=Ricinus communis
           RepID=B9SZR5_RICCO
          Length = 212

 Score =  125 bits (314), Expect = 3e-27,   Method: Composition-based stats.
 Identities = 36/121 (29%), Positives = 55/121 (45%), Gaps = 11/121 (9%)

Query: 18  PQILMPAL-RQL---EEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITA--GTNT 71
           P+ L P    +L   E +       PE   +  D+ + +  RPT L + + +     T  
Sbjct: 93  PEDLAPLFPDELIKQEASNEKFIDIPE---EVLDIYELW--RPTPLIRAKRLEKLLDTPA 147

Query: 72  TLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCR 131
            +Y K E +   G+HK N  + Q     + G   ++ ETGAGQ G + A A +L GL C 
Sbjct: 148 KIYYKYEGVSPAGSHKPNTAVPQVFYNAQQGIKNVVTETGAGQWGSSLAFACSLFGLGCE 207

Query: 132 I 132
           I
Sbjct: 208 I 208


>UniRef50_B9L1Z4 Threonine synthase n=1 Tax=Thermomicrobium roseum DSM 5159
           RepID=B9L1Z4_THERP
          Length = 411

 Score =  116 bits (290), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 68/345 (19%), Positives = 120/345 (34%), Gaps = 55/345 (15%)

Query: 57  TALTKCQNITAGTNTT-LYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           T L     +        L+LK E     G+ K+  +      A  +G    +A   AG  
Sbjct: 82  TPLLPAPRLARTLGLRRLWLKDESRNPTGSFKSRGLAVAVSRAIELGA-RAVALPSAGNA 140

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
             A +  +A  G+   +++    ++     V      GA V  V      L   C   +R
Sbjct: 141 AAALSAYAARAGIPAFVFL---PMDTPPSIVRECLAYGARVYRV----RGLITDCGRLVR 193

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
            ++   E     L T   P+       E ++ +G E   Q+     RLPD ++   GGG+
Sbjct: 194 RFAA--ERGWADLSTLREPYR-----AEGKKTMGFELVEQL---GWRLPDVIVYPTGGGT 243

Query: 236 NAIGMFADF--------INETNVGLI-----GVEPGGHGIETGEHGAPLKHGRVGIYFGM 282
             +GM   F        +  +    +     G  P       G   A    G   I  G+
Sbjct: 244 GIVGMEKAFAELAALGLLAGSRARFVIVQPEGCAPLVRAFHEGATRARPWEGAQTIAPGL 303

Query: 283 KAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLH 342
           + P    ++                      A + ++G    V+++D E LE  + L   
Sbjct: 304 RVPATIGDEL-------------------VLAAVRASG-GTAVAVSDQELLEGTRILATD 343

Query: 343 EGIIPALESSHALAHALKMMREN---PDKEQLLVVNLSGRGDKDI 384
           EG++ + E+   +A   ++       PD E +L +  SG    ++
Sbjct: 344 EGVLVSPEAGATVAAVRQLRANGWLAPDAEVVLFLTGSGLKHPEL 388


>UniRef50_Q58860 Probable threonine synthase n=38 Tax=Archaea RepID=THRC_METJA
          Length = 405

 Score =  115 bits (288), Expect = 3e-24,   Method: Composition-based stats.
 Identities = 78/333 (23%), Positives = 128/333 (38%), Gaps = 36/333 (10%)

Query: 57  TALTKCQNITAGTNTT-LYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           T L +C N+        LY+K E     G+ K   +      A  +G  E++     G  
Sbjct: 75  TPLYRCNNLEKELGIKELYVKNEGANPTGSFKDRGMTVGVTRANELGV-EVVGCASTGNT 133

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
             + A  SA  G KC + +    V             GA+VI V        DA +   +
Sbjct: 134 SASLAAYSARSGKKCIVLLPEGKVALGKLAQAM--FYGAKVIQVK---GNFDDALDMVKQ 188

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
               + E   Y+L +    +P+     E Q+ I  E   Q+     ++PD VI  VG   
Sbjct: 189 L---AKEKLIYLLNSI---NPF---RLEGQKTIAFEICDQL---NWQVPDRVIVPVGNAG 236

Query: 236 NAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIE 295
           N   ++  F      G+I   P   GI   +   P+          +            +
Sbjct: 237 NISAIWKGFKEFEITGIIDELPKMTGI-QADGAKPIVEAFRKRAKDIIPY---------K 286

Query: 296 ESYSISAGLD--FPSVGPQH--AYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALES 351
              +I+  +    P   P+   A  +S G A+  ++TD+E +EA K L   EGI     S
Sbjct: 287 NPETIATAIRIGNPVNAPKALDAIYSSGGYAE--AVTDEEIVEAQKLLARKEGIFVEPAS 344

Query: 352 SHALAHALKMMREN-PDKEQLLVVNLSGRGDKD 383
           + ++A   K++ E   D+++ +V   +G G KD
Sbjct: 345 ASSIAGLKKLLEEGIIDRDERIVCITTGHGLKD 377


>UniRef50_O05626 Tryptophan synthase beta subunit (Fragment) n=1 Tax=Streptomyces
           flavovirens RepID=O05626_9ACTO
          Length = 107

 Score =  112 bits (281), Expect = 2e-23,   Method: Composition-based stats.
 Identities = 43/82 (52%), Positives = 59/82 (71%), Gaps = 1/82 (1%)

Query: 307 PSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENP 366
           P +GP+HAYL   GR +Y ++TDD A+ A + L   EGIIPA+ES+HALA AL++ +E  
Sbjct: 1   PGIGPEHAYLKDVGRGEYRAVTDDAAMRALRLLSRTEGIIPAIESAHALAGALEVGKEL- 59

Query: 367 DKEQLLVVNLSGRGDKDIFTVH 388
             + L++VNLSGRGDKD+ T  
Sbjct: 60  GTDGLILVNLSGRGDKDMDTAA 81


>UniRef50_A5EK00 L-threonine synthase n=11 Tax=Bacteria RepID=A5EK00_BRASB
          Length = 413

 Score =  110 bits (276), Expect = 9e-23,   Method: Composition-based stats.
 Identities = 68/334 (20%), Positives = 131/334 (39%), Gaps = 39/334 (11%)

Query: 57  TALTKCQNITAGTNT-TLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           T L     ++       + +K E  L  G+ K   ++    + K +G T +   T     
Sbjct: 90  TPLINLPKLSKKLGGGEIIVKDEGRLPTGSFKARGLVMAVSMGKALGITHMAMPTNGNAG 149

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
              +A A++  G+K  I+  A   E    NV  + L GA V  V+     L D C + + 
Sbjct: 150 AALAAYATS-CGIKTTIFCPADTPE---VNVSEIELQGATVYRVN----GLIDDCGKIVG 201

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
           +         +   T   P+       E ++ +G E   Q+      +PD +    GGG+
Sbjct: 202 EGKAKV--GWFDTSTLKEPYRI-----EGKKTMGLELAEQL---GWDVPDVIFYPTGGGT 251

Query: 236 NAIGMFADFINETNVGLIGVE-PGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQI 294
             IGM+  F     +G IG + P    ++       ++    G+    +           
Sbjct: 252 GLIGMWKAFDELEKIGFIGSKRPRMVAVQASGCAPMVRAYEAGVEHATR----------W 301

Query: 295 EESYSISAGLDFP-SVGPQH---AYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALE 350
           E++++I++G+  P +VG      A   S G A  +++ DD+   A   +   EG++   E
Sbjct: 302 EDAHTIASGIRVPQAVGDFLILRAVRESKGFA--IAVDDDKISSALSEVAREEGLLLCPE 359

Query: 351 SSHALAHALKMMREN--PDKEQLLVVNLSGRGDK 382
            +   A   + + +      +++++ N +  G K
Sbjct: 360 GAATYAAYKQSLADGRVTKNDRVMLFNCA-TGLK 392


>UniRef50_C5CDJ9 Pyridoxal-5'-phosphate-dependent protein beta subunit n=33 Tax=root
           RepID=C5CDJ9_KOSOT
          Length = 475

 Score =  109 bits (272), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 69/336 (20%), Positives = 116/336 (34%), Gaps = 52/336 (15%)

Query: 57  TALTKCQNITA--------GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIA 108
           T L + +NIT         G    +++K E     G+ K  +      +AK++G   +IA
Sbjct: 63  TNLIELKNITKLVRYISEPGKGARIFVKDEASNPSGSFKDRRASVSVYMAKKLGYEGVIA 122

Query: 109 ETGAGQHGVASALASALLGLKCRIYMGAKDVER-QSPNVFR----MRLMGAEVIPVHSGS 163
            T +G +G + A  +A  GLKC I     D      P +          GAEV+ +  G 
Sbjct: 123 AT-SGNYGASVASQAAKRGLKCIIVQETYDSNGIGQPEILEKGRACETYGAEVVQLTVGP 181

Query: 164 ATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRL 223
                   E    +    E   Y   +   P+    +       +G E   Q  E+ G  
Sbjct: 182 --------ELFYYFLVLLEETGYFNASLYTPYGIAGV-----ETLGYEIALQCREQIGCD 228

Query: 224 PDAVIACVGGGSNAIGMFADFI--NETNVGLIGVEPGGHGI----ETGEHGAPLKHGRVG 277
           PD V+    GG N  G     +     N  ++      HG+    +   +      G  G
Sbjct: 229 PDYVVVTHAGGGNLTGTARGLLKAGAKNTKIVAASVDLHGLHMASDRDFNRKSFTTGHTG 288

Query: 278 IYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFK 337
             FG+   +        + +   +  L +                 Y+ +T  E     +
Sbjct: 289 --FGIPFAVYPDRSDVPKNA---ARALRYMD--------------RYLLVTQGEVFYVTE 329

Query: 338 TLCLHEGIIPALESSHALAHALKMMRENPDKEQLLV 373
            L   EG+      + +LA A+ + RE P    ++V
Sbjct: 330 MLARLEGMQRGPAGNTSLAAAISLARELPKDNIVVV 365


>UniRef50_Q0W7Y3 Threonine synthase n=2 Tax=Euryarchaeota RepID=Q0W7Y3_UNCMA
          Length = 413

 Score =  106 bits (266), Expect = 1e-21,   Method: Composition-based stats.
 Identities = 84/355 (23%), Positives = 136/355 (38%), Gaps = 50/355 (14%)

Query: 57  TALTKCQNITAGTN-TTLYLKREDLLHGGAHKTNQV---LGQAL--LAKRMGKTEIIAET 110
           T L + +NI        L+ K E L   G+ K       + QA   L         I   
Sbjct: 78  TPLVRSRNIAREPGFGELFFKLESLNPTGSFKDRGSTVEISQAYHYLCHHGECENEIVCA 137

Query: 111 GAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDAC 170
             G  G + A   A  G++C IY+     + +     +M   GAE++ V         A 
Sbjct: 138 STGNMGASVAAYCARGGIRCTIYVPNDTAKIKL---LQMMAHGAEIVRVDGDYTV---AM 191

Query: 171 NEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIAC 230
           + A R++    E   Y+    AG +PY     E ++ +G E   Q+      +PD ++  
Sbjct: 192 HTAKREY---EERGRYL----AGDYPY---RGEGEKSVGLEVIDQL----NGVPDYIVCP 237

Query: 231 VGGGSNAIGMFADFINETNVGL-------IGVEPGGHGIETGEHGAPLKHGRVGIYFGMK 283
           +G G+   G++         GL       IGV+ GG            + GR  I     
Sbjct: 238 IGNGTLVHGIWKGLKELKITGLLQRLPKIIGVQAGGC----NTVARSFEEGRDDI----- 288

Query: 284 APMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHE 343
            P++      + ++ +    LD        A   S G A  VS  D E   A   L   E
Sbjct: 289 TPVV---PHTLMDAVACGDPLD--GTWALRAIRESEGWATAVS--DVEGARARDLLGKKE 341

Query: 344 GIIPALESSHALAHALKMMR-ENPDKEQLLVVNLSGRGDKDIFTVHDILKARGEI 397
           GI   L  + ++A  +K  + E  +K+  +V  ++G G K+  T  D ++  GE+
Sbjct: 342 GIFAELSGALSMAGLIKAYQAEVIEKDARVVALVTGHGLKEPETFEDEIRTIGEL 396


>UniRef50_C1E0J2 Predicted protein n=1 Tax=Micromonas sp. RCC299 RepID=C1E0J2_9CHLO
          Length = 477

 Score =  105 bits (263), Expect = 2e-21,   Method: Composition-based stats.
 Identities = 74/338 (21%), Positives = 122/338 (36%), Gaps = 40/338 (11%)

Query: 57  TALTKCQNITAGTNTT----LYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGA 112
           T +     + A         L +K E  L  G+ K   ++    +AK +G T +   T  
Sbjct: 143 TPIVDAPKLAAEAGLEEGGALLVKDEGRLPTGSFKARGLVMAVSMAKELGVTRMAMPTN- 201

Query: 113 GQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNE 172
           G  G A +   +  G++  I+      +    N+  M L GA V  V+       D C +
Sbjct: 202 GNAGAAMSAYCSRCGIETYIFAPEDTPD---TNIREMALQGANVWRVN----GYIDDCGK 254

Query: 173 ALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVG 232
            +    G  E   +   T   P+       E ++ +G E   Q       LPD ++   G
Sbjct: 255 IV--GGGKEEMNWFDTSTLKEPYRI-----EGKKTMGLELVEQFG--WDDLPDVIMYPTG 305

Query: 233 GGSNAIGMFADFINETNVGLIGVE---PGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQT 289
           GG+  IGM+  F     +GLI  E   P    ++       +     G  F  +      
Sbjct: 306 GGTGLIGMWKAFGELKELGLIKPETKLPKMVAVQATGCAPMVNAYDAGEEFATRV----- 360

Query: 290 EDGQIEESYSISAGLDFP-SVGP--QHAYLNSTGRADYVSITDDEALEAFKTLCLHEGII 346
            D     S   + G+  P +VG       +  +G    V++TDD   E        EG +
Sbjct: 361 -DNAFTRS---AMGIRVPAAVGDFLILRAVRESG-GWAVAVTDDAIDEGQTEFAKKEGFL 415

Query: 347 PALESSHALAHALKMMRENPDK--EQLLVVNLSGRGDK 382
              E +   A   K +     K  +++L+ N +  G K
Sbjct: 416 LCPEGAATYAAFKKGLANGKIKKTDRVLLFNCA-TGLK 452


>UniRef50_A3DKY8 Transcriptional regulator n=1 Tax=Staphylothermus marinus F1
           RepID=A3DKY8_STAMF
          Length = 436

 Score =  102 bits (255), Expect = 2e-20,   Method: Composition-based stats.
 Identities = 69/336 (20%), Positives = 118/336 (35%), Gaps = 61/336 (18%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T L +  N+    N  +Y K E     G+ +          A   G   ++  +  G  G
Sbjct: 67  TPLIRSDNLFR--NENIYFKDESRNPTGSFRDRAAALIVSDALDQGAKRLVVASD-GNMG 123

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD 176
            + A  SA  GL   IY     V      +  M+  GA+VI       TL        R 
Sbjct: 124 ASIAAYSAKAGLPVTIY---VPVWTDPEKILLMKAYGAKVIVSEEDLDTLLQYVERRARK 180

Query: 177 WSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSN 236
                 ++ Y +           +  E  + IG E   Q     G +P  V   +G G  
Sbjct: 181 EKLYNASSTYNI-----------LAMEGLKTIGYEIYLQ----YGGVPSTVYVPLGSGLT 225

Query: 237 AIGMFADFIN-------ETNVGLIGVEPGGHGIETGEHGAPLKHGR---VGIYFGMKAPM 286
            + ++  F         +    LIGVE   + + +  HG P K       G+Y+  + P+
Sbjct: 226 ILSLYHGFSEMHSNNIIDHIPKLIGVETCANPVYSSIHGNPTKCNEEPMPGLYY--RKPV 283

Query: 287 MQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGII 346
           ++    +I + +                        + + + + +   A K L + EG+ 
Sbjct: 284 LKEYVSEIIDKH-----------------------GETIVVNNKQVYMAAKKLAMEEGLF 320

Query: 347 PALESSHALAHALKMMRENPDKEQLLVVNLSGRGDK 382
               S+ ALA ALK+      +  +++  L+G G K
Sbjct: 321 VEPSSAVALAGALKI---GGTENSIIL--LTGHGLK 351


>UniRef50_B6YXA7 Hypothetical threonine synthase (TS) n=1 Tax=Thermococcus
           onnurineus NA1 RepID=B6YXA7_THEON
          Length = 389

 Score = 98.8 bits (245), Expect = 3e-19,   Method: Composition-based stats.
 Identities = 75/339 (22%), Positives = 126/339 (37%), Gaps = 35/339 (10%)

Query: 57  TALTKCQNITAGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           T L + + +      + LY+K E     GA K      +   A      ++I  +  G  
Sbjct: 80  TRLYRAKRLEEKIGISKLYIKNEGENPTGAFKDRGSSVEITKALEFHAQKVIVAS-TGNM 138

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
             + +   A  GLK  I +     E +     + ++ GA V        T  +A  EA R
Sbjct: 139 AASISAYGAKAGLKVTIVVPEGTPEGKL---VQAKMYGANV---EVFGKTYDEALAEAER 192

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
               + E  +Y+ G             E Q+  G E   Q+      +PD ++  +G G+
Sbjct: 193 ---RALEDGYYLTGN-------YHYRVEGQKTTGFEIIDQLH---FNVPDWIVVPIGAGT 239

Query: 236 NAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIE 295
           +   ++        +GLI   P   G++          G   I    K      +  +  
Sbjct: 240 HLRAIWKGLKEFYRIGLISELPRIAGVQI--------EGYDSIVRAWKTSKPIEKITKKV 291

Query: 296 ESYSISAGLDFPSVGPQH--AYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSH 353
            + + +  +  P  G     A   S G  D  ++T++E   A   L   EG+     S+ 
Sbjct: 292 PTIASAIAVKAPVDGENVLKAVKESNGYLD--TVTNEETAAAGLLLGR-EGLFVEPSSAT 348

Query: 354 ALAHALKMMREN-PDKEQLLVVNLSGRGDKDIFTVHDIL 391
           +LA A KM  E   DK + +V+  +G G KDI T   +L
Sbjct: 349 SLALAQKMREEGIIDKGESVVIIATGHGLKDINTWSKVL 387


>UniRef50_Q1IJB6 L-threonine synthase n=2 Tax=Bacteria RepID=Q1IJB6_ACIBL
          Length = 396

 Score = 98.1 bits (243), Expect = 5e-19,   Method: Composition-based stats.
 Identities = 71/334 (21%), Positives = 123/334 (36%), Gaps = 32/334 (9%)

Query: 65  ITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASA 124
           + +  +  +++K E L   G+ K   +     +A+  G  +I A   AG    A A   A
Sbjct: 76  LPSRKHANVFIKDEGLNPTGSFKARGLGMGVTMARFYGVKKI-AIPSAGNAASALAAYCA 134

Query: 125 LLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETA 184
              ++  I+M          N       GA V  V      L   C + + +        
Sbjct: 135 AAKIEAHIFMPKDVPMA---NRIECESYGAHVTYVD----GLISDCAKMVAE--RKQAEG 185

Query: 185 HYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADF 244
            + + T   P        E ++ +G E   Q+      LPDA+I   GGG   +GM+  F
Sbjct: 186 WFDISTLKEPFRV-----EGKKTMGYEVAEQL---GWELPDAIIYPTGGGVGLLGMWKAF 237

Query: 245 INETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGL 304
                +G IG +            AP+              M +        +++ +AGL
Sbjct: 238 EEMEQLGWIGSKRPKMICAQATGCAPVVKAWE--EHRETMEMWKD-------AHTSAAGL 288

Query: 305 DFPS--VGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMM 362
             P      +  +         V++TDDE + AF +    EG+  A E + ALA   K++
Sbjct: 289 RVPKPYADREILHAMKASGGTAVAVTDDEIMAAFSSWAREEGVFAAPEGAAALAAYWKLI 348

Query: 363 REN--PDKEQLLVVNLSGRGDKDIFTVHDILKAR 394
                  +E++++ N +G G K I       + +
Sbjct: 349 ESGYLRPEEKVVLFN-TGSGLKYIDVFEKYFRKK 381


>UniRef50_UPI00016C3ADC threonine synthase n=1 Tax=Gemmata obscuriglobus UQM 2246
           RepID=UPI00016C3ADC
          Length = 445

 Score = 97.7 bits (242), Expect = 7e-19,   Method: Composition-based stats.
 Identities = 70/359 (19%), Positives = 127/359 (35%), Gaps = 62/359 (17%)

Query: 57  TALTKCQNITAGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           T L  C  +      + LY+K E  L  G+ K+  +     +AK +G   +   T     
Sbjct: 79  TPLLHCPRLGRQLGLSQLYVKDESQLPTGSFKSRGMAAAISMAKWLGVKRVALPTAGNA- 137

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
           G A+A  +A  G++C ++M          N F  +L GA+   V+     L + C + ++
Sbjct: 138 GGAAAAYAARAGIECFVFMPHDTPS---VNQFEAQLYGAKAFRVN----GLINDCGKIVK 190

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQI------------------- 216
           D +       + L T   P+       E ++ +G E   Q                    
Sbjct: 191 DGAERM--GWFDLSTLKEPYR-----LEGKKTMGLELAEQFGRGLQGEPTGGSPSPAARG 243

Query: 217 ----------LEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGE 266
                          +LPD +    GGG+  +GM+  F     +G +   P   G  +G 
Sbjct: 244 LQREPANGSPSPGSWQLPDVIFYPTGGGTGLVGMWKAFAELAELGWLRATP---GHASGI 300

Query: 267 HGAPLKHGRVGIYFGMKAPMMQTEDGQ-----IEESYSISAGLDFP-SVGP--QHAYLNS 318
               L   +     G    +   + G+        + ++++GL  P +VG       + +
Sbjct: 301 RFPRLISCQ---AEGCAPIVTAYQKGERFAELFPNARTVASGLRVPVAVGDFMILDAIRA 357

Query: 319 TGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKM--MRENPDKEQLLVVN 375
           +G    V   + E     +     EGI    E++       +M    E    E+++V N
Sbjct: 358 SG-GTAVLGRESEIARWMQRASSAEGISICPETAVCFDALERMVAAGEVKPDERVVVFN 415


>UniRef50_C9RSS0 Threonine synthase n=13 Tax=Bacteria RepID=C9RSS0_GEOSY
          Length = 405

 Score = 97.7 bits (242), Expect = 7e-19,   Method: Composition-based stats.
 Identities = 68/349 (19%), Positives = 121/349 (34%), Gaps = 57/349 (16%)

Query: 57  TALTKCQNITAGTNTT-LYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           T L     +        LY+K E ++  G  K          AK +G  ++   T  G  
Sbjct: 81  TPLVPMMRLGRKIGIEALYMKDEGVIPTGTFKARGAAVGVSKAKELGVKQLAMPTN-GNA 139

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
           G A +L +A  G++  + M    V+          + GAE+  V+   +       +A+R
Sbjct: 140 GAAWSLYAARAGIQATVVM---PVDAPELTRKECAIAGAELYLVNGLISDAGQIVAKAIR 196

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
           ++        Y   T   P+       E ++ +G E   Q      +LPD ++   GGG 
Sbjct: 197 EY------GWYDASTLKEPYRI-----EGKKTMGLEIAEQFS---WQLPDVILYPTGGGV 242

Query: 236 NAIGM--------FADFINETNVGLIGVE-----PGGHGIETGEHGAPLKHGRVGIYFGM 282
             IG+           +++     L+ V+     P     +  +  +        + FG+
Sbjct: 243 GLIGIYKAIKELQALGWVDGRMPRLVAVQAEHCAPIVKAWKEKKRESKFWPNAHTVAFGI 302

Query: 283 KAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLH 342
             P    +   +E  Y                          +++ D+  L   +T    
Sbjct: 303 NVPKALGDFLVLEAVYETDG--------------------CAIAVNDEAILAEQRTAAEL 342

Query: 343 EGIIPALESSHALAHALKMMRENP---DKEQLLVVNLSGRGDKDIFTVH 388
           EG     E   A   A + +RE+    D E ++V+N +G G K   TV 
Sbjct: 343 EGAFICPE-GAAAFAAARTLRESGWIRDGETVVVLN-TGTGLKYADTVD 389


>UniRef50_A0LFH6 Cysteine synthases n=15 Tax=cellular organisms RepID=A0LFH6_SYNFM
          Length = 773

 Score = 96.9 bits (240), Expect = 1e-18,   Method: Composition-based stats.
 Identities = 71/323 (21%), Positives = 120/323 (37%), Gaps = 57/323 (17%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK---TEIIAETGAG 113
           T L +   +      TLY K E    GG+ K    L     A+R G     +II E  +G
Sbjct: 15  TPLIRINRLNPNPAVTLYAKLEAKNPGGSIKDRTALFMIESAERDGLLTHEKIIIEATSG 74

Query: 114 QHGVASALASALLGLKCRIYMGAK-DVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNE 172
             G+  A+ +A+ G +  + M     +ERQ      ++ +GAE++       T  D   E
Sbjct: 75  NTGIGLAIVAAVKGYRLMLAMPETASLERQK----ILKALGAEILLTPGNLGT--DGAIE 128

Query: 173 ALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVG 232
            +          +YM      P         F    G E   Q    EG++   V+    
Sbjct: 129 KVYSLVRENPDRYYMPDQFNNPANPAAH--HFGT--GPEIFEQ---TEGKVNTVVVTLGT 181

Query: 233 GGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTED 291
            G+ A+G+       +  + ++GVEP                     Y G +   ++   
Sbjct: 182 TGT-AMGILQAMKERDPAIRVVGVEP---------------------YPGHRVQGLKN-- 217

Query: 292 GQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALES 351
             ++ESY        P +  +HA          + I D++A E  + L   EGI   + S
Sbjct: 218 --MKESYV-------PGIFDRHA------LDQIIHIKDEDAFEMARRLAREEGIFTGMSS 262

Query: 352 SHALAHALKMMRENPDKEQLLVV 374
             A+A A+++  E  +   + V+
Sbjct: 263 GAAMAIAVRVAEEMREGIVVAVL 285


>UniRef50_C6A3C7 Threonine synthase n=6 Tax=cellular organisms RepID=C6A3C7_THESM
          Length = 380

 Score = 95.8 bits (237), Expect = 3e-18,   Method: Composition-based stats.
 Identities = 72/328 (21%), Positives = 123/328 (37%), Gaps = 36/328 (10%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T LTK + ++      LYLK E L    + K          A  +G  +I      G   
Sbjct: 64  TPLTKAKRLSKELGVELYLKNETLNPTWSFKDRGTFIGIHRALELGFNKIGT-VSTGNMA 122

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD 176
            + A   A  GL+  I + +  VE +      + + GA+VI V      L        R 
Sbjct: 123 ASVAAYGARFGLETYILVSSTIVEEKLK---ALEVYGAKVIKVRGDYGGLY------YRS 173

Query: 177 WSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSN 236
                    Y + +       P  V  ++  IG E   ++       PD V+     G  
Sbjct: 174 LEIGQRKGIYFINS-----DDPFRVEGYKS-IGFEIAEEVT------PDYVVIPTSSGGL 221

Query: 237 AIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEE 296
             G+   F+     GLI   P    +   E  +P+          ++         + E 
Sbjct: 222 FRGIVKGFLELKESGLIEDLPTFVAV-QAEGCSPICKAFNESRQKIE---------RFEN 271

Query: 297 SYSISAGLD--FPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHA 354
            ++I+  ++  +P  G     L +  +   V+++D+E LEA + L   EGI     S+  
Sbjct: 272 PHTIAHAIENPYPPSGNAVLRLLNELKGLCVAVSDEEILEAQQDLGR-EGIFVQPASATG 330

Query: 355 LAHALKMMRENPDKEQLLVVNLSGRGDK 382
           +A A+K +R   +++  +V  L+G G K
Sbjct: 331 IA-AIKKLRGRIEEDTKVVSILTGSGLK 357


>UniRef50_B5E900 Cysteine synthase n=1 Tax=Geobacter bemidjiensis Bem
           RepID=B5E900_GEOBB
          Length = 354

 Score = 92.7 bits (229), Expect = 2e-17,   Method: Composition-based stats.
 Identities = 70/339 (20%), Positives = 122/339 (35%), Gaps = 67/339 (19%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK---TEIIAETGAG 113
           T + +  ++       +  K E    GG+ K        L A+  G+    ++I E  +G
Sbjct: 7   TPVAEIYSLCKNPAVRIVAKLEGNNPGGSVKDRPARQMILAAEASGELTPDKVILEPTSG 66

Query: 114 QHGVASALASALLGLKCRIYMGA-KDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNE 172
             G+A A+ +A  G + ++ M A   VER       +   GAE++          +A + 
Sbjct: 67  NTGIALAMIAAARGYRIKLVMPACVSVER----RSVLEAYGAEIVLSPG-----CEATDG 117

Query: 173 ALR---DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIA 229
           A+R            +YM       +  P  V    +  G E   Q     G     V+A
Sbjct: 118 AIRLAHKILAEDPAKYYMP----NQYANPNNVLAHYKTTGPEIWHQ----TGGEVTHVVA 169

Query: 230 CVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQ 288
            +G     +G+ + F   + +V ++GVEP                       G K   ++
Sbjct: 170 GMGTSGTLMGLASYFKEVKPSVQVVGVEPT---------------------LGHKIQGLK 208

Query: 289 TEDGQIEES-YSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIP 347
                I    Y  +A   +                  + + DD+A E  + L  HEGI  
Sbjct: 209 NMKEAIVPPIYDCAA---YH---------------RNLVVEDDDAFETARLLAAHEGIFC 250

Query: 348 ALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFT 386
            +    A+  AL++  E      ++VV +  RGD+ + T
Sbjct: 251 GMSGGAAVFGALQLASELSSG--VIVVIVPDRGDRYLST 287


>UniRef50_B2KE33 Threonine synthase n=1 Tax=Elusimicrobium minutum Pei191
           RepID=B2KE33_ELUMP
          Length = 416

 Score = 92.7 bits (229), Expect = 2e-17,   Method: Composition-based stats.
 Identities = 64/346 (18%), Positives = 122/346 (35%), Gaps = 44/346 (12%)

Query: 57  TALTKCQNITAGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           T +   + +      + L +K E     G+ K          A  +G   IIA+   G  
Sbjct: 81  TPMYDHKELADELGISKLLIKDEGRNPTGSIKDRGSAVSVARALELGLD-IIADASTGNA 139

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
             + A  +A L +K  ++        +   +F   + GA+V  V        + C +A+ 
Sbjct: 140 SDSLACLTAGLDIKTIVFTTKDAPYPKLTQLF---VYGADVFTVDGTYDDAFELCKKAVE 196

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
           ++        Y    AAG +P+    RE ++    E   Q+       PD V+  VG G+
Sbjct: 197 EY------GWY--SRAAGYNPF---TREGKKTCSFEICEQL---NWEAPDKVLVAVGDGT 242

Query: 236 NAIGMFADFIN-------ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQ 288
              GM+  F++       E    +I V+  G   +  +             F  K  +  
Sbjct: 243 ILSGMWKGFVDFQKLGILEKMPQMIAVQAEGS--DAIKRA-----------FENKGEVTA 289

Query: 289 TEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPA 348
            +   I +S  +    ++P                 V++TD+E L A         I   
Sbjct: 290 VKAHTIADSILV----NYPRDAQLAVQALQESDGYAVTVTDEEILAAIPEFARKANIFAE 345

Query: 349 LESSHALAHALKMMRENP-DKEQLLVVNLSGRGDKDIFTVHDILKA 393
              +   A   K+  E   ++++ + + + G G KD ++    ++ 
Sbjct: 346 PAGAAVYAALKKLAEEGKIEQDETVAIVIGGNGLKDTYSYAKNIQK 391


>UniRef50_B0VGY7 Putative threonine synthase n=1 Tax=Candidatus Cloacamonas
           acidaminovorans RepID=B0VGY7_9BACT
          Length = 392

 Score = 92.7 bits (229), Expect = 2e-17,   Method: Composition-based stats.
 Identities = 65/323 (20%), Positives = 122/323 (37%), Gaps = 37/323 (11%)

Query: 66  TAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASAL 125
           TA   T L++K + L   G++K          A + G  EI+  +  G    + A   A 
Sbjct: 96  TASNYTKLWIKFDGLNPSGSYKDRASQLVVADALQKGIKEIVTAS-TGNAACSLACLGAS 154

Query: 126 LGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAH 185
            GLK  I+            + ++++  AE+  +     +  DA   AL          H
Sbjct: 155 AGLKVVIFAPQ---NAPPAKLIQIQVHNAELHKID---GSYDDAFKAALEY-----TKTH 203

Query: 186 YMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFI 245
             +    G HP   +  + ++  G E   Q      ++PD ++  VG G    G++  F+
Sbjct: 204 NCMCRNTGYHP---LTIDGKKSAGIEIYVQ---NGYKVPDWIVIPVGDGVILTGIYKAFL 257

Query: 246 NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLD 305
           +    G+    P    ++     A   +   GIY   + P+   +  +++          
Sbjct: 258 DLKKAGITEKMPHLLCVQAESSDAITSYWETGIYHDAENPITIADSIKVKT--------- 308

Query: 306 FPSVGPQHAYLNSTGRADY----VSITDDEALEAFKTLCLHEGIIPALESSHALAHALKM 361
                P  A+ +     +     + ++D E  EA   L    G+     SS  LA   K+
Sbjct: 309 -----PALAHWSVKALKETDGKCIRVSDKEIQEAQLELAKETGVFSEPSSSATLAGLKKV 363

Query: 362 MRENPDKE-QLLVVNLSGRGDKD 383
           +  +  K+ + +V+ ++G G KD
Sbjct: 364 VNHSWLKDAKDIVLLITGHGLKD 386


>UniRef50_B4AUD2 Threonine synthase, putative n=23 Tax=Francisella
           RepID=B4AUD2_FRANO
          Length = 598

 Score = 92.3 bits (228), Expect = 3e-17,   Method: Composition-based stats.
 Identities = 78/337 (23%), Positives = 123/337 (36%), Gaps = 47/337 (13%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T L K + I       LY K E     G+ K         +AK +G   I+  +  G   
Sbjct: 75  TPLLKSKIIGKELGINLYFKVEGKNPTGSFKDRGSAVDITVAKELGAKGIVLAS-TGNMA 133

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA--L 174
            + A  +A   + C I +       +   V      G +++ V       K + NEA  L
Sbjct: 134 ASCACYAAAAKMPCFIIVPEGVAASKLAQVM---SYGGKIVQV-------KGSYNEAAKL 183

Query: 175 RDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGG 234
                  +         AG + +     E Q+    E   Q+L +   +PD VI  +G G
Sbjct: 184 AYDIAKSKDFF-----LAGDYAF---RVEGQKTAAFELIDQLLFQ---VPDEVIIPIGCG 232

Query: 235 SNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQI 294
           +N    +  F     +G I   P   G+++ E    L                Q    +I
Sbjct: 233 TNMTAYYKGFCEYKELGFINSLPKLTGVQSTE-ADTLARA------------YQKNQNRI 279

Query: 295 EE---SYSISAGLD--FP--SVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIP 347
           E    + +I+  +   +P        A  ++ G  +  ++TD + LEA   L   EG+  
Sbjct: 280 EPLKTANTIATAIAVPYPIDGDKAIDAIYSTGG--ESTAVTDMKMLEAQYLLSTKEGLFV 337

Query: 348 ALESSHALAHALKMMREN-PDKEQLLVVNLSGRGDKD 383
            L S+  +AH LK   E    K   +V  LSG G KD
Sbjct: 338 ELASASTIAHLLKKYEEGRLQKGSTVVCVLSGEGLKD 374


>UniRef50_A2ETD5 Threonine synthase family protein n=1 Tax=Trichomonas vaginalis
           RepID=A2ETD5_TRIVA
          Length = 429

 Score = 91.9 bits (227), Expect = 4e-17,   Method: Composition-based stats.
 Identities = 74/357 (20%), Positives = 126/357 (35%), Gaps = 43/357 (12%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T L       +     L++K E      + K        + AK +GKT ++    +G   
Sbjct: 80  TPLIPVPQDRSPFKIQLWIKDEGREPTASLKDRASALVCVKAKELGKT-VVTTASSGNAA 138

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD 176
            A++   A LGLK  I+            V + RL GA V  V         A   A+  
Sbjct: 139 AATSCMCACLGLKPVIF---VPAHAPPAKVLQNRLYGATVFLVE---GVYDRAVEAAM-- 190

Query: 177 WSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILE-----------REGRL-- 223
              + + + Y   T   P+       + ++ +  E   Q+               G+L  
Sbjct: 191 -GAAKKYSWYNRSTGFNPY-----TIDGKKTVSFEICEQLGGILCPEETKGECSWGKLGK 244

Query: 224 ---PDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYF 280
              PDA++  VG G+   G+          GLI   P   G++     +        I  
Sbjct: 245 FVAPDAIVVSVGDGNIISGVHKGLKELFAAGLIEKVPKIIGVQAEGSNSVYVCWSQKIDP 304

Query: 281 GMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGR-ADYVSITDDEALEAFKTL 339
                    E   + +S S     D     P  A+  +T     YV +TD+E L A  T+
Sbjct: 305 VNMPVC---EGSTLADSISCPTPND-----PIRAFRAATETNGAYVQVTDEEILAAIPTM 356

Query: 340 CLHEGIIPALESSHALAHALKMMREN--PDKEQLLVVNLSGRGDKDIFTVHDILKAR 394
               GI P   ++   A   K  ++      E++++++ +G G KDI      ++ +
Sbjct: 357 ARATGIFPEPAAAAGFAGIFKAEQQGYLKPGEKVVMIS-TGNGLKDINNATKSMEGK 412


>UniRef50_D2S0A7 Threonine synthase n=6 Tax=Halobacteriaceae RepID=D2S0A7_9EURY
          Length = 419

 Score = 90.7 bits (224), Expect = 7e-17,   Method: Composition-based stats.
 Identities = 73/343 (21%), Positives = 121/343 (35%), Gaps = 44/343 (12%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T L    N++        +K +     G  K          AK  G+  II     G   
Sbjct: 84  TDLFDAPNLSEALGVETLVKDDGRNPTGCFKDRASSIAVTKAKHAGRD-IITCASTGNAA 142

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD 176
            + +  +A  GL CRI++       +        + GA+V+ V+        + +EA   
Sbjct: 143 ASLSGYAARGGLDCRIFVPGAAPAGKLAQPL---VYGADVLAVNG-------SYDEAYDL 192

Query: 177 WSG-SYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
               + E   Y    A  P        E +R +G E   Q   R G +PD V+  +G G 
Sbjct: 193 SVEVTDEYGWYNRNAAINPFQV-----EGKRTVGHELAEQSKVR-GDVPDWVVFSMGDGC 246

Query: 236 NAIGMFADFIN-------ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQ 288
              G +  F         +    ++GV+  G    +  H A    G   I     A  + 
Sbjct: 247 TIAGAWKGFKEFYDLDYVDDYPKMLGVQAEG---ASAIHDA--FQGHEDID--DIAETIA 299

Query: 289 TEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPA 348
                     +I A        P+     S G  D V ++D++ LEA K L   EGI   
Sbjct: 300 DSIAVGRPRNTIKA-----CRAPE----QSGG--DTVLVSDEDILEAEKLLGSTEGIYAE 348

Query: 349 LESSHALAHALKMMREN-PDKEQLLVVNLSGRGDKDIFTVHDI 390
              +  +A   + ++    ++++ +VV  +G G KD  +    
Sbjct: 349 PAGATPVAGVREALKRGIIERDETVVVVSTGFGLKDTESAKKA 391


>UniRef50_Q8U4P9 Threonine synthase n=1 Tax=Pyrococcus furiosus RepID=Q8U4P9_PYRFU
          Length = 304

 Score = 90.7 bits (224), Expect = 8e-17,   Method: Composition-based stats.
 Identities = 79/325 (24%), Positives = 120/325 (36%), Gaps = 39/325 (12%)

Query: 57  TALTKCQNITAGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           + L +   +    N + +YLK E       HK          AK +G + I   T  G +
Sbjct: 14  SPLLRAMKLEEKLNISKIYLKLEMHNPTRTHKDRIAKAHVKQAKDLGFSGITVGT-CGNY 72

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA-- 173
           GVA A  +   G+K  I++     + ++  V  M+  GA+VI V         A  EA  
Sbjct: 73  GVAIAYFAKKEGIKAVIFVPR---QYRNSRVEEMKEYGADVIFVDG-------AYEEAVL 122

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
           +          +        P   P +  E   +I +E   +I       P AV   VG 
Sbjct: 123 MSKIFAKTMNYYDA-----NPGTQPAVDYEAYSLISKEILEEIE------PYAVFVPVGN 171

Query: 234 GSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQ 293
           GS   G++  F         GV P   G+ T      L     G    +K   ++T+  +
Sbjct: 172 GSTLAGIYYGF------KKYGVMPRIIGVTTSYGNQVLNAFYTGRVEEVK-DFVETDFNE 224

Query: 294 IEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSH 353
              S SIS  L         A  +S G        DD AL+  K L + EGI     S+ 
Sbjct: 225 PLVS-SISFDLQNA----LEAIKDSNGYI--FGFGDDTALKYAKILEMSEGIKALPASTL 277

Query: 354 ALAHALKMMRENPDKEQLLVVNLSG 378
            L   +K +R+     +  V+ L+G
Sbjct: 278 TLVGLVKFVRKFGVNNENFVLLLTG 302


>UniRef50_B6A2K1 Pyridoxal-5'-phosphate-dependent protein beta subunit n=8
           Tax=Proteobacteria RepID=B6A2K1_RHILW
          Length = 323

 Score = 90.4 bits (223), Expect = 1e-16,   Method: Composition-based stats.
 Identities = 70/350 (20%), Positives = 117/350 (33%), Gaps = 60/350 (17%)

Query: 55  RPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQ 114
           R T L + + I       LYLK E L   GA K    L + L   R      +  + +G 
Sbjct: 22  RHTPLLRAEKIEKAVGCQLYLKPETLQITGAFKIRGALNKVLSLPREEIANGVIASSSGN 81

Query: 115 HGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEAL 174
           H    + A+ +LG+K  + +     + +  N    R +GAEVI     +A       E  
Sbjct: 82  HAQGLSYAARILGVKVILVLPVTTPKIKIANT---RALGAEVILFDGDTAARWKKVYE-- 136

Query: 175 RDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGG 234
                + E  +  +     P     +V   Q  IG E    +        D VI  VGGG
Sbjct: 137 ----IAEENNYATIHGFEDP-----LVMAGQGTIGCEILEDL-----DDVDTVIVPVGGG 182

Query: 235 SNAIGMFADFIN-ETNVGLIGVEPGGHG------IETGEHGAPLKHGRVGIYFGMKAPMM 287
               G+       + +V ++G EP          I       PLK+              
Sbjct: 183 GLISGIATAIKETKPSVRVVGAEPALTPKYFHSRINKERTSLPLKN-------------- 228

Query: 288 QTEDGQIEESYSISAGLDFPSVG----PQHAYLNSTGRADYVSITDDEALEAFKTLCLHE 343
                      +I+ GL     G    P           + V + D++ +   ++L    
Sbjct: 229 -----------TIADGLRISVPGQNPYPIIEKYVD----EIVLVDDEDIIAGMRSLARDA 273

Query: 344 GIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDK-DIFTVHDILK 392
            +I    +S  +   L    +    E++  V   G  D  D+  ++ + +
Sbjct: 274 KLITEPAASIGIGALLAGSIKVRPDEKVCAVLTGGNWDLCDLAEIYKVFE 323


>UniRef50_D1B950 Pyridoxal-5'-phosphate-dependent protein beta subunit n=1
           Tax=Thermanaerovibrio acidaminovorans DSM 6589
           RepID=D1B950_THEAS
          Length = 301

 Score = 89.6 bits (221), Expect = 2e-16,   Method: Composition-based stats.
 Identities = 59/329 (17%), Positives = 117/329 (35%), Gaps = 59/329 (17%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE---IIAETGAG 113
           T L   +N +      ++ K E L   G+ K    L     A+  G+ +    + E  +G
Sbjct: 12  TPLVLLRNSSTNPKVKIWAKLEMLNPSGSLKDRVALSMVEGAEARGELKPGMTLVEATSG 71

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
             G+A  + +A+ G K +I+M      +       ++  GA+++       T KD  +  
Sbjct: 72  NTGIALGMVAAVKGYKLKIFMSE---AKTIERRKILKYWGADLVL------TTKDDPDSH 122

Query: 174 L---RDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIAC 230
           +     ++  +    Y        +     V   +R  G E   Q+ +  G   DA +A 
Sbjct: 123 ILSAMAYAKEHPDCFY-----VNQNENRDNVEAHRRGTGIEIIEQLHQH-GEKVDAFVAG 176

Query: 231 VGGGSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQT 289
            G G   +G+   F+++  +  + GVEP            P   G  G+    +A     
Sbjct: 177 FGTGGCLMGVAKAFVDKGVSAKVYGVEPM-----------PNTGGIDGLKHRSEAY---- 221

Query: 290 EDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPAL 349
                                P  A    +  A  + ++ D+A+   +++   EGI+  +
Sbjct: 222 --------------------QPLIAD--RSLLAGIIDVSRDDAIAGARSISAKEGIMAGM 259

Query: 350 ESSHALAHALKMMRENPDKEQLLVVNLSG 378
            S   L  A ++ +       +++    G
Sbjct: 260 SSGATLHAAQELAKTMESGNIVVIFGDRG 288


>UniRef50_A3DKP7 L-threonine synthase n=2 Tax=Desulfurococcaceae RepID=A3DKP7_STAMF
          Length = 423

 Score = 89.6 bits (221), Expect = 2e-16,   Method: Composition-based stats.
 Identities = 75/342 (21%), Positives = 124/342 (36%), Gaps = 35/342 (10%)

Query: 57  TALTKCQNITAGTNTT-LYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           T L K   +        LYLK E     G+ K   +     +AK  G    +  +     
Sbjct: 80  TPLIKANRLAEKLGLKNLYLKDETRNPTGSFKDRCMSVSVSMAKYFGFKRAVVASSGN-- 137

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPV---HSGSATLKDACNE 172
             A+ALA+        +Y    D       + ++   GA+V  V    +   T+K     
Sbjct: 138 -AAAALAAYGARAGIEVYAFVPDFAG-YGKIAQLLFYGAKVFRVRWVEAEDPTVKM---- 191

Query: 173 ALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVG 232
            +R  +  Y    Y   +     P+     E  + I  E   Q+      +PD V    G
Sbjct: 192 -MRLLAEKY--GFYPSPSF---GPFNPYQIEGPKTIAMEIVEQL---GWDVPDQVFVPTG 242

Query: 233 GGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDG 292
             S   G++  F +  NVG I   P    ++   +   ++            P  +    
Sbjct: 243 AASLLTGVYNGFRDWNNVGWINKYPRMVAVQPEGNHPFVRAWMEKADPNKIKPWEK---- 298

Query: 293 QIEESYSISAGLD--FP--SVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPA 348
                 +I+ GL+  FP        A  N+ G    V ++D+E LEA K L   EG+   
Sbjct: 299 ---PPETIATGLEDTFPWDGDAGLRALYNTNGYG--VVVSDEEILEAMKLLASLEGLFAE 353

Query: 349 LESSHALAHALKMMRENP-DKEQLLVVNLSGRGDKDIFTVHD 389
              +  LA  +K + +   D+++ +VV ++G G KD   V  
Sbjct: 354 PSGAAGLAGLIKALEDGKVDRDETIVVLVTGHGLKDPDIVKK 395


>UniRef50_B0TBV3 Threonine synthase n=1 Tax=Heliobacterium modesticaldum Ice1
           RepID=B0TBV3_HELMI
          Length = 413

 Score = 89.2 bits (220), Expect = 2e-16,   Method: Composition-based stats.
 Identities = 66/344 (19%), Positives = 116/344 (33%), Gaps = 52/344 (15%)

Query: 57  TALTKCQNITAGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           T L +   +    +    ++K E      + K        L A   G + I   +  G  
Sbjct: 84  TPLYRASRLAETLDVADCWVKDEGRNPTASFKDRASAVGVLKAMERGASRITCAS-TGNA 142

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS---GSATLKDACNE 172
             + A  +A  GL   I++  +  E +   V ++ + GA+V  V      +  L  A + 
Sbjct: 143 ASSLAGFAAAAGLPASIFVPKRAPEAK---VAQLLVFGAQVFSVQGTYDQAWELCMAASS 199

Query: 173 ALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVG 232
               ++ +     Y++              E ++ +  E   Q  ER G  PD V+  VG
Sbjct: 200 HFGWYNRNCAINAYLI--------------EGKKTVALELVEQFRER-GAFPDWVVVSVG 244

Query: 233 GGSNAIGMFADFIN-------ETNVGLIGVEPGGH--GIETGEHGAPLKHGRVGIYFGMK 283
            G    G++  F         E    ++GV+  G    +     G  L            
Sbjct: 245 DGCTIGGVWKGFKEMQRIGWIEKTPKILGVQAAGCQPFVTAWREGKRLTPCEADTLADSI 304

Query: 284 APMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHE 343
           A         +    +   GL         A   S G   YV++ D   LEA  TL    
Sbjct: 305 A---------VGHPRNFVKGLR--------AVTESGG--AYVAVPDQAILEAMTTLARKA 345

Query: 344 GIIPALESSHALAHALKMMREN-PDKEQLLVVNLSGRGDKDIFT 386
            +      +  +A   +  R+     + ++ V ++G G KDI +
Sbjct: 346 AVFGEPAGATGVAGVQEARRQGIIGPDDVVAVIVTGNGLKDIAS 389


>UniRef50_B3T1L2 Putative Pyridoxal-phosphate dependent enzyme n=1 Tax=uncultured
           marine microorganism HF4000_010I05 RepID=B3T1L2_9ZZZZ
          Length = 356

 Score = 89.2 bits (220), Expect = 3e-16,   Method: Composition-based stats.
 Identities = 71/334 (21%), Positives = 122/334 (36%), Gaps = 40/334 (11%)

Query: 57  TALTKCQNITAGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           T   + Q+         LY K E L   G+ K         +A+  G  EI+ E  +G  
Sbjct: 52  TPCVELQSTGEFLGLCGLYGKLEFLNPTGSFKDRGTAIMISVAREQGVAEIV-EDSSGNA 110

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
           G + A  +A  G++  I++ A     +     ++++ GA+   V            EA  
Sbjct: 111 GASVAAYAARTGIRAHIFVPASAPAAKIQ---QIKVYGAQTHSVEG--------PREATT 159

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
           D + ++   H   G     H       E  +    E  +Q       LP+ ++  VG GS
Sbjct: 160 DAAVAFSNEH---GLVYASHNLSPYFIEGTKTFPYEVASQW---ADDLPEHLVIPVGNGS 213

Query: 236 NAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIE 295
             IG +  F    + G I   P  H ++       +   R G            E     
Sbjct: 214 LFIGAWKGFQELLDGGQISKMPRIHCVQAMAISPIVAAYRGG------------EWSPKA 261

Query: 296 ESYSISAGLDFPSVGP-----QHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALE 350
            + +++ G+   S  P       A L +T     V++ ++E LE    L   EGI     
Sbjct: 262 GARTVAGGI--ASASPPRKPQMLAVLGATDGV-AVAVEEEEILEWQLQLARREGIYAEPT 318

Query: 351 SSHALAHALKMMRENP-DKEQLLVVNLSGRGDKD 383
           S+ A A   +++        + ++V ++G G KD
Sbjct: 319 SAAAFAGLARLVEMGTIRSSETVLVPITGSGLKD 352


>UniRef50_Q5WD43 Threonine synthase n=4 Tax=Bacillus RepID=Q5WD43_BACSK
          Length = 376

 Score = 88.8 bits (219), Expect = 3e-16,   Method: Composition-based stats.
 Identities = 68/329 (20%), Positives = 123/329 (37%), Gaps = 35/329 (10%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAK--RMGKTEIIAETGAGQ 114
           T L       +     +Y+K + L+   + K        L+AK   +G T +IA++ +G 
Sbjct: 77  TPLLPV----SADKPNVYVKVDYLMPTLSFKDRGAA--VLIAKALELGATSVIADS-SGN 129

Query: 115 HGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEAL 174
            G A +  +A  G+ C ++              +M    A+V  +    A  ++    A 
Sbjct: 130 AGTAVSAYAARAGIACEVF---CSNTVSPKKQAQMAAYNAKVHTI----AGTREDVARAA 182

Query: 175 RDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGG 234
           +  + + E   +       P+ Y     E  +    E   Q+    G  PD VI  VG G
Sbjct: 183 QQKAANLEEGGFYASHVYNPYFY-----EGTKTYAYEIYEQL----GDAPDTVIIPVGNG 233

Query: 235 SNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQI 294
           +  +G +  F       LIG  P    +   +  APL H        +   + QT    I
Sbjct: 234 TLLLGAYYGFSELLANRLIGKCPKIVAV-QAQQCAPLAHAFATGEPSITPIVGQT---TI 289

Query: 295 EESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHA 354
            E  +I+A    P        + +TG   ++++++ +  +A   L   +G      +S A
Sbjct: 290 AEGIAIAAP---PRATQILEAVRNTG-GTFITVSEAQIAKARSALAK-QGFDVEP-TSAA 343

Query: 355 LAHALKMMRENPDKEQLLVVNLSGRGDKD 383
              AL + R    +  ++ +  SG    D
Sbjct: 344 TYAALHVYRHCETETIVIPLCGSGTKASD 372


>UniRef50_A9B1I1 Response regulator receiver protein n=1 Tax=Herpetosiphon
           aurantiacus ATCC 23779 RepID=A9B1I1_HERA2
          Length = 545

 Score = 88.8 bits (219), Expect = 3e-16,   Method: Composition-based stats.
 Identities = 78/348 (22%), Positives = 113/348 (32%), Gaps = 74/348 (21%)

Query: 57  TALTKCQNITAGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE-IIAETGAGQ 114
           T L   Q          LY+K E      + K  Q              E +IA TG   
Sbjct: 75  TPLLHAQRFGGLLGLPRLYIKDERYSPTNSFKDRQAALAVAALVSNDIRECVIASTGNAA 134

Query: 115 HGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEAL 174
             VA A A A +G+K  ++M +   E +        L GAEVI V       K      +
Sbjct: 135 --VAYASACAAVGIKLWVFMTSVVPEAKL---REAALFGAEVIKVSGNYDQTKQ-----I 184

Query: 175 RDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGG 234
                      Y  G  + P       RE  + I  E   Q+     + PD  I  V GG
Sbjct: 185 AADFAQNRNIIYDRGANSIP------AREAMKTISYEICEQL---GWQAPDWYIQAVSGG 235

Query: 235 SNAIGMFADFINETNVGLI------------GVEPGGHGIETGEHGAP----------LK 272
              +G++  F     +GL             G  P     + G+  A           L 
Sbjct: 236 LGPLGVYHGFAELHAMGLTQRVPQTAIIQAEGCSPMVQAFQAGKSVAEKVVPNTRIAILS 295

Query: 273 HGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEA 332
            G  G  +      +QT  G +                               ++TD+EA
Sbjct: 296 TGDPGKIYTRLWQRIQTSGGTM------------------------------EAVTDEEA 325

Query: 333 LEAFKTLCLHEGIIPALESSHALAHALKMMRENP-DKEQLLVVNLSGR 379
             A + L   EGI     ++ A A   KM+ +   + E+L+VVN +G 
Sbjct: 326 FSAMRLLARTEGISVEPATAVAFAGLQKMVAQGQVNPEELIVVNCTGH 373


>UniRef50_C5CHS7 Threonine synthase n=2 Tax=Thermotogaceae RepID=C5CHS7_KOSOT
          Length = 419

 Score = 88.4 bits (218), Expect = 4e-16,   Method: Composition-based stats.
 Identities = 68/372 (18%), Positives = 123/372 (33%), Gaps = 54/372 (14%)

Query: 41  FQAQFNDLLKNYAGRPTALTKCQNITAGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAK 99
               F++L+       T L +   I        + +K +      + K        + AK
Sbjct: 71  LPENFDELIPPLLVGNTPLYRADKIAGKYGVAEVLVKDDGRNPTASFKDRASALAVVKAK 130

Query: 100 RMGKTEII-AETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIP 158
             G   +  A TG     +A   A+A  GLK  I++ A     +     ++++ GA+V+ 
Sbjct: 131 EKGYNTVFCASTGNAASSLAGLTAAA--GLKSVIFVPASAPAAKL---TQLQVYGAKVLA 185

Query: 159 VHSGSATLKDACNEALR-DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQIL 217
           +         + +EA         E   Y   +A  P+     + E ++    E   Q  
Sbjct: 186 IDG-------SYDEAFDISMIVGMEKGWYCRNSAINPY-----LLEGKKTGALELAVQTG 233

Query: 218 EREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVG 277
                LPD V   VG G+     +  F++   +G+I   P   G++     A +     G
Sbjct: 234 M---DLPDFVFVSVGDGTVLSSFYKAFMDLKELGIIERIPTIVGVQAENASAIIDTYERG 290

Query: 278 IYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSIT--------- 328
                             E ++ +  LD  SV    A             T         
Sbjct: 291 ------------------EPFTPA-DLDAHSVADSIAVGKPRDVIKACKYTKKNGGLFVK 331

Query: 329 --DDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQL-LVVNLSGRGDKDIF 385
             D E L++   L    G+      + A A   +M       E   + + ++G G KD+ 
Sbjct: 332 VSDKEILDSIIELARGTGVFAEPAGATAFAGFKRMKSLGQISESARVALIVTGNGLKDLK 391

Query: 386 TVHDILKARGEI 397
               +L+   ++
Sbjct: 392 APARVLEELKKL 403


>UniRef50_Q9K7E3 Threonine synthase n=82 Tax=cellular organisms RepID=THRC_BACHD
          Length = 354

 Score = 88.4 bits (218), Expect = 4e-16,   Method: Composition-based stats.
 Identities = 74/332 (22%), Positives = 115/332 (34%), Gaps = 45/332 (13%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T L   +N++       Y+K E     G+ K   ++     AK  G   II  +  G   
Sbjct: 31  TPLIPLENLSKEWGVKAYVKYEGANPTGSFKDRGMVMAVAKAKEEGSRTIICAS-TGNTS 89

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD 176
            A+A   A  GL+C + +    +         M   GAEV+ +           + AL  
Sbjct: 90  AAAAAYGARAGLRCIVVIPEGKIALGKLAQAVM--YGAEVLEIKGN-------FDHALDI 140

Query: 177 WSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSN 236
                E     L  +  P+       E Q+    E    +    G+ PD +   VG   N
Sbjct: 141 VRSISEKEPITLVNSVNPYRI-----EGQKTSAFEICDAL----GQAPDVLAIPVGNAGN 191

Query: 237 AIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEE 296
               +  F         G+ P   G E  E  A +   +V                 IEE
Sbjct: 192 ITAYWKGFKEYHEKKGTGL-PQMRGFE-AEGAAAIVRNQV-----------------IEE 232

Query: 297 SYSISAGLDFPSVG----PQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESS 352
             +I+  +   +         A   S G+ D   +TD+E L A++ L   EG+     S 
Sbjct: 233 PETIATAIRIGNPASWTYAVEAAAESNGKID--EVTDEEILAAYQLLAQKEGVFAEPASC 290

Query: 353 HALAHALKMMRENPDKEQLLVVN-LSGRGDKD 383
            ++A   K +     K+   VV  L+G G KD
Sbjct: 291 ASIAGLRKQIASGEIKKGSTVVCVLTGNGLKD 322


>UniRef50_C1TP96 Threonine synthase n=1 Tax=Dethiosulfovibrio peptidovorans DSM
           11002 RepID=C1TP96_9BACT
          Length = 378

 Score = 88.4 bits (218), Expect = 5e-16,   Method: Composition-based stats.
 Identities = 78/342 (22%), Positives = 124/342 (36%), Gaps = 37/342 (10%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T L               +K + L   G++K   +       + +G T +I E  +G  G
Sbjct: 72  TPLIPV----ELDGVKPLVKMDFLCPTGSYKDRGISVLVSRLRELGITSLI-EDSSGNAG 126

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD 176
            A A      GL C +Y+   D       V ++   GAE+I V        DA   A R+
Sbjct: 127 AAMAAYCTAGGLNCSVYVP--DYTSAGKCV-QIEAYGAELIRVPGTREDTTDAAMAAARE 183

Query: 177 WSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSN 236
                   +Y  G+      +   V+ F      E   Q+       PD ++  +G GS 
Sbjct: 184 -------TYY--GSHNWSPWFVEGVKTF----AYEIWEQL---GWTAPDHLVLPLGQGSL 227

Query: 237 AIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEE 296
            +G +       ++GLI   P  HG+++  + APL         G+  P   T+   + E
Sbjct: 228 VLGAYRALSELRDMGLIDHIPKIHGVQSA-NCAPLAR---AYESGLDVPENITKAETVAE 283

Query: 297 SYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALA 356
             S +  L     G +        R   V++ +   +E    L    GI     S+  + 
Sbjct: 284 GISSATPLR----GAEVLEAVKRSRGSIVAVDEKPIVEGIFALASR-GIYVEPTSAVVVP 338

Query: 357 HALKMMRENP-DKEQLLVVNLSGRGDKDIFTVHDILKARGEI 397
              K+M      K +  VV LSG G K       IL+ R +I
Sbjct: 339 GISKLMESGAISKGETTVVFLSGSGLK---ATDKILELRRKI 377


>UniRef50_C6A3D2 Threonine synthase n=2 Tax=Thermococcus RepID=C6A3D2_THESM
          Length = 312

 Score = 88.1 bits (217), Expect = 5e-16,   Method: Composition-based stats.
 Identities = 72/327 (22%), Positives = 120/327 (36%), Gaps = 36/327 (11%)

Query: 58  ALTKCQNITAGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
            L + Q +      + +Y+K E     G HK            ++G + I   T  G +G
Sbjct: 14  PLIRAQKLEEYLGISKIYIKLESFNPTGTHKDRIARVHVEEVNKLGFSAITTGT-CGNYG 72

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD 176
           ++ A  +   GLK  I++           +  +   GAEV+ ++    + ++A  E+ + 
Sbjct: 73  ISIAYFAQKYGLKAHIFIPRAYSN---IRLKELEKYGAEVVFIN---GSYEEAVFESKKF 126

Query: 177 WSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSN 236
              + E   Y     A P   P I  E    I  E    +       P AV   VG G+ 
Sbjct: 127 ---AKENNIYD----ANPGSKPWIDYEGYAAISREIAKNVT------PYAVFVPVGNGTT 173

Query: 237 AIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEE 296
            +G++  F        +G  P   G+ T   G  + +      F       +T+  +   
Sbjct: 174 LVGIYHGF------RQLGFTPHMIGV-TTSFGNQVLNAFYTKSFDEVKDFAETKFNEPLV 226

Query: 297 SYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALA 356
           S SIS   D        A  +S G        DD + +    L   EGI     S+  LA
Sbjct: 227 S-SISFDFDNA----LEAIYDSDGYV--FGFADDVSFKYAYLLERFEGIKAFPASALVLA 279

Query: 357 HALKMMRENPDKEQLLVVNLSGRGDKD 383
             +K +++     +  V+ L+G G KD
Sbjct: 280 GLVKFVKKFGVNGRNFVLILTG-GLKD 305


>UniRef50_A8MAW5 Threonine synthase n=1 Tax=Caldivirga maquilingensis IC-167
           RepID=A8MAW5_CALMQ
          Length = 391

 Score = 88.1 bits (217), Expect = 6e-16,   Method: Composition-based stats.
 Identities = 81/383 (21%), Positives = 145/383 (37%), Gaps = 58/383 (15%)

Query: 20  ILMPA-LRQLE-EAFVSAQKDPEFQAQFNDLLKNYAGRPT------ALTKCQNITAGTNT 71
            LM A L +L  +  +  ++     + ++ LL     R T       L     I+ G   
Sbjct: 51  SLMEAILAELPKDIKLRYRRRLGVWS-YSQLLPEPKNRVTLNEGGTPLI---RISKGL-- 104

Query: 72  TLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCR 131
             + K E L   G+ K   +     LAK +G + I+  +       ASA   A  GL+  
Sbjct: 105 --FGKFEGLNPTGSFKDRGMAIGVSLAKAIGVSNIVVASTGNTAASASAY-GARAGLRAI 161

Query: 132 IYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTA 191
           + + +  V R       +   GA ++ +        DA  EA+           +  G A
Sbjct: 162 VLLPSGKVARGKLAQSII--HGASIMSID---GYFDDALTEAM---------NMFKAGKA 207

Query: 192 AGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVG 251
              +       E Q+ I  E    I     ++PD VI  VG   N   ++  F     +G
Sbjct: 208 YSLNSINAWRLEGQKSIAYEIYEDI-----KVPDNVIVPVGNAGNIYAIWKGFWELMQIG 262

Query: 252 LIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGP 311
           LI   P   G++        +  R G           +E  +++E  ++++ +    +G 
Sbjct: 263 LIDKVPRMIGVQAEGASPLYETWRRG----------SSELIEVKEPKTVASAIR---IGK 309

Query: 312 QHAYLNSTGRAD-----YVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMREN- 365
              +L +    +      V++ D+E + A   L    GI     S+   A  +K++R + 
Sbjct: 310 PVNWLKALKAVNNSGGLLVTVNDNEIMIARGRLARR-GIFVEPASASTYAAYIKLIRNSV 368

Query: 366 -PDKEQLLVVNLSGRGDKDIFTV 387
             + E+ ++V L+G G KD  +V
Sbjct: 369 ISNDERTVLV-LTGHGLKDPDSV 390


>UniRef50_A5V1I5 L-threonine ammonia-lyase n=2 Tax=Roseiflexus RepID=A5V1I5_ROSS1
          Length = 321

 Score = 87.7 bits (216), Expect = 7e-16,   Method: Composition-based stats.
 Identities = 80/338 (23%), Positives = 127/338 (37%), Gaps = 42/338 (12%)

Query: 56  PTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           PT L +   + A T     LK E+    G+ K    L   L      +   I    +G H
Sbjct: 21  PTPLDESIRLGALTGGRALLKLENTQPTGSFKVRGALNVLLALPHHVRERGIVAASSGNH 80

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
           G A A  +  LG    I++           V  MR  GA+V           D C  A R
Sbjct: 81  GAAVAYGALTLGAPALIFVPEDT---SPVKVDAMRDFGADV-------RMYGDDCVVAER 130

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
            ++ +Y T H +  T   P+  P +V   Q  IG E   QI        DA++  VGGG 
Sbjct: 131 -YARAYATEHGL--TYISPYNDP-LVIGGQGTIGVELARQIDRL-----DAILVAVGGGG 181

Query: 236 NAIGMFADFIN--ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQT-EDG 292
              G+   ++   + +V +IG  P    I +      +  G V     +  P++ T  DG
Sbjct: 182 LISGIAT-YMKAVQPDVRIIGCSP----INSPAMYESVLAGEV-----VSPPILPTLSDG 231

Query: 293 QIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESS 352
                   +  LD          L  T   ++V +++DE   A + +   +  +    + 
Sbjct: 232 TAGGVEPDAITLD----------LCRTLVDEWVLVSEDEIAAAMRLMIETQHTLVEGSAG 281

Query: 353 HALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDI 390
            A+A  L++  E   K   +V+  S      + TV D+
Sbjct: 282 VAVAGYLRLKDEMRGKTAAIVICGSNVSLATLRTVIDM 319


>UniRef50_B9JX06 Threonine dehydratase n=16 Tax=Alphaproteobacteria
           RepID=B9JX06_AGRVS
          Length = 416

 Score = 87.3 bits (215), Expect = 9e-16,   Method: Composition-based stats.
 Identities = 73/348 (20%), Positives = 123/348 (35%), Gaps = 59/348 (16%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQ---------VLGQALLAKRMGKTEII 107
           T L   ++++   N  +YLKREDL    ++K             LGQ          +I 
Sbjct: 20  TPLQLSEHLSTLFNANIYLKREDLTPVRSYKVRGAYNFFRKVIALGQI--------DKIF 71

Query: 108 AETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLK 167
               AG H    A A    G+   ++M     +++       R  GAE I +        
Sbjct: 72  VCASAGNHAQGFAFACRHFGVHGVVFMPVTTPQQKIDKT---RKFGAEFITIRLVGDIF- 127

Query: 168 DACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAV 227
           D C +A RD+    +      G    P  +  I+ E Q  +  E   Q+ E     PD V
Sbjct: 128 DQCYKAARDYVEEAD------GLMVPPFDHADII-EGQATVAAEILEQLSEEV--TPDLV 178

Query: 228 IACVGGGSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPM 286
           I  VGGG  + GM      +      +  EP G           LK              
Sbjct: 179 IMPVGGGGLSAGMTGYLAEDLPLSAFLFAEPVG--------APSLKRSL----------- 219

Query: 287 MQTEDGQIEESYSISAGLDFPSVGPQ----HAYLNSTGRADYVSITDDEALEAFKTLCLH 342
              E G++     +   +D  +V        A L     A  + + ++        +   
Sbjct: 220 ---EAGEVITLPKVDNFVDGAAVARIGDANFAALKHFPPAQVMLVPENAICGTIIDMLNV 276

Query: 343 EGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDI 390
           EG++     + A+A    + R + + + +++V +SG G+ D   + D+
Sbjct: 277 EGVVLEPAGALAIATLGLLERSSIEGKTVVLV-VSG-GNFDFERLPDV 322


>UniRef50_C1PE10 Threonine dehydratase n=2 Tax=Bacillaceae RepID=C1PE10_BACCO
          Length = 350

 Score = 87.3 bits (215), Expect = 9e-16,   Method: Composition-based stats.
 Identities = 72/342 (21%), Positives = 115/342 (33%), Gaps = 42/342 (12%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T L +         T LY K E+L   G+ K    L +        +   +    AG H 
Sbjct: 41  TPLNESATFNEMAGTRLYFKMENLQRTGSFKIRGALNKITNLTGDARKNGVIAASAGNHA 100

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD 176
              A ++   GLK +IYM  K    +   V   +  GAEV+          ++  EA   
Sbjct: 101 QGVAFSATKQGLKAKIYMPEKTPLAK---VLATKAYGAEVVLT-------GESFQEAYEA 150

Query: 177 WSGSYETAHYMLGTAAGPHPYPTI-VREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
                +     +  A   HP+    V   Q  I  E   Q  +      D V+  VGGG 
Sbjct: 151 AVLDQQ-----ITGATFIHPFDDYEVMAGQGTIALEMIQQCADL-----DTVVIPVGGGG 200

Query: 236 NAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQI 294
              GM     N +  + +IGV+  G           + + R+    G+   ++  E GQ+
Sbjct: 201 LIAGMACLLKNYDPKIRVIGVQSEGAP-AAYNRFKGMGNSRLEHVSGIADGILVKETGQL 259

Query: 295 EESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHA 354
                           P  +        D V+++D++   A   +   E +      + A
Sbjct: 260 TF--------------PLISKYVD----DVVTVSDEDIATAIIYMLEREKMFVEGAGAAA 301

Query: 355 LAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKARGE 396
            A  L        K   +VV+  G  D D  +    L   G+
Sbjct: 302 FAAVLSGKAGVSGKHVGIVVSG-GNADLDKISHFKRLATAGK 342


>UniRef50_D1BQL6 Cysteine synthase n=9 Tax=Firmicutes RepID=D1BQL6_VEIPT
          Length = 304

 Score = 87.3 bits (215), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 72/322 (22%), Positives = 116/322 (36%), Gaps = 56/322 (17%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK---TEIIAETGAG 113
           T + +  N      T +Y+K E    GG+ K   VLG    AK  G+     II E  +G
Sbjct: 15  TPIYQLPN------TNIYVKLEKYNVGGSVKDRAVLGMLQAAKEQGRIHENSIIVEATSG 68

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
             G+A A+  A+L +K  I M    + ++      ++  GA++I     +  +K A   A
Sbjct: 69  NTGIALAMVGAILHIKTVIIMPE-SMSKE--RRELIKAYGAQLILTPKETG-MKGALERA 124

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
             +    Y  A + LG    P   P +     R  G E   Q+        D  IA +G 
Sbjct: 125 -NEILAKYPNA-FTLGQFVNPA-NPDM---HYRTTGNEIVEQVP-----NVDVFIAGIGT 173

Query: 234 GSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDG 292
           G    G+         N+  I VEP G           +  G+ G         +Q    
Sbjct: 174 GGTFTGVTRRLKEHNPNLKAIAVEPAG--------SPAITEGKGG------PHKIQGIGA 219

Query: 293 QIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESS 352
                    + +D   V                +++D+EA    +T     GI   L + 
Sbjct: 220 GFIPENFDQSLMD--GV---------------QTVSDEEAFSEVQTFMRESGISIGLSAG 262

Query: 353 HALAHALKMMRENPDKEQLLVV 374
            A+  A ++ RE P    +++ 
Sbjct: 263 AAIVAAKRIAREEPKANIVVIA 284


>UniRef50_D1Y7Y8 Threonine synthase n=1 Tax=Pyramidobacter piscolens W5455
           RepID=D1Y7Y8_9BACT
          Length = 409

 Score = 87.3 bits (215), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 82/382 (21%), Positives = 133/382 (34%), Gaps = 62/382 (16%)

Query: 34  SAQKDPEFQAQFNDLL---KNYAGRPT------ALTKCQNITAGTNT-TLYLKREDLLHG 83
           S   DP F     + L   +  + RPT       L     I +  +   L +K +     
Sbjct: 50  SLAADPRFSLWRYEALLPMRKNSRRPTLQVGWTPLYDMPQIASEYDVGQLLIKDDGRNPT 109

Query: 84  GAHKTN-QVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQ 142
            + K     +   L A+R    +++A    G    + A  +A +GLK  I++       +
Sbjct: 110 ASLKDRASAVAVTLAAER--NRDVLACASTGNAASSLAGFAANMGLKSVIFVPETAPVAK 167

Query: 143 SPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYET-AHYMLGTAAGPHPYPTIV 201
              V ++ + GA V  V       K     A+R    + E    Y    A  P      +
Sbjct: 168 ---VTQLLVFGARVFLV-------KGDYAAAVRLAIEAIEHYGWYDRNCAINP-----FL 212

Query: 202 REFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHG 261
            E ++    E   Q       +PD V   VG G      +  F +   +G+I   P   G
Sbjct: 213 VEGKKTCAMEIAEQCD---WDVPDKVFVSVGDGCIVSSTYKGFYDLYKIGVIDRIPQIIG 269

Query: 262 IETGEHGA---PLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGP------- 311
           ++          ++ G   I FG               S++I+  +D   VG        
Sbjct: 270 VQAEGACPIHRAIQEGADKIVFG--------------PSHTIADSID---VGAPHNWAKA 312

Query: 312 QHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDK-EQ 370
            HA   S G  D  +++D E L A   L    G+      + A A  +K  RE   K   
Sbjct: 313 LHAIRASHG--DTTAVSDAEILSAVAELPRKSGVFAEPAGATAYAGFVKFAREGRLKASD 370

Query: 371 LLVVNLSGRGDKDIFTVHDILK 392
            + V +SG G KD+ +    + 
Sbjct: 371 RVAVIISGNGLKDVASAQKAVP 392


>UniRef50_C4RAY2 Threonine synthase n=1 Tax=Micromonospora sp. ATCC 39149
           RepID=C4RAY2_9ACTO
          Length = 407

 Score = 86.9 bits (214), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 72/343 (20%), Positives = 116/343 (33%), Gaps = 55/343 (16%)

Query: 57  TALTKCQNITAGTNTT-LYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           T L +     A      L +K E L   G+ K          A+ +G   I   T  G  
Sbjct: 89  TPLLRAPAYGARIGIPDLIVKDEGLTPTGSFKARGAAVGVSRARELGVRRIAMPTN-GNA 147

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
           G A A  +A  GL   I M           V      G ++  V      L       + 
Sbjct: 148 GAAWATYAARAGLASTIVMPLDAPAICRREVLAA---GGDLRLVD----GLISDAGRHVA 200

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
               S   A +  GT   P+       E ++ +G E   Q+     ++PD ++   GGG 
Sbjct: 201 ALVASSAGAVFDAGTLREPYR-----LEGKKTMGYEIVEQL---GWQVPDVIVYPTGGGV 252

Query: 236 NAIGMFAD--------FINETNVGLIGVEPGG-----HGIETGEHGAPLKHGRVGIYFGM 282
             IG+           +I +    L+ V+  G          GE  A        + +G+
Sbjct: 253 GLIGIHKAMHELRELGWITDRPPRLVAVQSTGCAPIVRAFAAGEDRARPWTDARTVAYGI 312

Query: 283 KAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLH 342
             P    ++  I E+   SAG                     +++ D E L   +   + 
Sbjct: 313 TVPAPLGDEL-ILEALRASAG-------------------TAIAVDDAEILADLRDFGVD 352

Query: 343 EGIIPALESSHALAHALKMMRENP---DKEQLLVVNLSGRGDK 382
           EG++   E   A   A + +RE       E+++V+N +G G K
Sbjct: 353 EGLLLCPE-GAACLTAARHLREGGWIRAGERVMVLN-TGSGLK 393


>UniRef50_Q1QC42 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit n=41
           Tax=Bacteria RepID=Q1QC42_PSYCK
          Length = 326

 Score = 86.5 bits (213), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 67/341 (19%), Positives = 117/341 (34%), Gaps = 38/341 (11%)

Query: 44  QFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK 103
           + ++ +K Y  R T +   + +       ++ K E+    GA K                
Sbjct: 18  EAHERIKPYIHR-TPVLTSRFLNELAGCEMFFKCENFQKAGAFKVRGASNAVFGLSDEDA 76

Query: 104 TEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGS 163
              +    +G H ++ + A+   G+ C + M     E +   V   R  G  +I     S
Sbjct: 77  KNGVCTHSSGNHALSLSYAAGQRGIPCNVVMPHSAPEAKKAAV---RGYGG-IITECEPS 132

Query: 164 ATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRL 223
            T ++     ++  +G         G    P+  P  V   Q     E   Q+ E  G  
Sbjct: 133 TTSREEVFAKVQAETG---------GDFVHPYNDPR-VIAGQATCSREFLEQM-EEIGEK 181

Query: 224 PDAVIACVGGGSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGM 282
           PD V+A +GGG    G      N   +V +   EP    +   +     K G +      
Sbjct: 182 PDMVVAPIGGGGMISGTCLTLSNLAPDVKIYAAEP----LNADDAARSFKAGHIIAD--- 234

Query: 283 KAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLH 342
                       +   +++ GL  P +     +  S    D ++ T++E +EA K    H
Sbjct: 235 ------------DAPNTVADGLKVP-LKDLTWHFVSNYVTDILTATEEEIVEAMKLTWTH 281

Query: 343 EGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKD 383
             II     +  LA  LK       K+  +++   G  D D
Sbjct: 282 MKIIIEPSCAVPLAVILKNKDVFAGKKVGVIITG-GNVDLD 321


>UniRef50_A1S0F3 Threonine synthase-related protein n=1 Tax=Thermofilum pendens Hrk
           5 RepID=A1S0F3_THEPD
          Length = 325

 Score = 86.5 bits (213), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 69/328 (21%), Positives = 109/328 (33%), Gaps = 29/328 (8%)

Query: 57  TALTKCQNITAGT---NTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAG 113
           T L K  ++          +YLK E     G HK    L     A   G   +   T  G
Sbjct: 16  TPLLKLTSLRKLLNLDGAAVYLKYEGYNPTGTHKDRAALAHVGEAVLNGYDTVTVGT-CG 74

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
            +GVA A  + L GL+  I++           V  M+  GA V+ V  G      A +  
Sbjct: 75  NYGVAVAYYARLAGLRAVIFVPKGYSNS---RVPEMKRYGARVVEVE-GPYEDAVAVS-- 128

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIV-REFQRMIGEETKAQILEREGRLPDAVIACVG 232
               S +     Y     A P      V  E   +I  E   Q+    G  P  V   VG
Sbjct: 129 ---VSSARANGWYD----ANPGSVNDHVSIEAYSLIAREIVRQL----GDAPAVVAVPVG 177

Query: 233 GGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDG 292
            G+  +G++  F      G    E            +           G   P +  E  
Sbjct: 178 NGTTLVGIYHGFYRLYRAG----ETTRIPRMVAASTSNANQLVYSWSRGSTEP-LPVEVS 232

Query: 293 QIEESYSISAGLDFPSVGPQHAYLN-STGRADYVSITDDEALEAFKTLCLHEGIIPALES 351
           ++ E+      +   S+  + A       +      +D E +E    L   EG+     S
Sbjct: 233 EVRETPVNEPLVAIRSLNAEEALRAIYASKGAAFGFSDSEMVEMSILLRAFEGVSALPAS 292

Query: 352 SHALAHALKMMRENPDKEQLLVVNLSGR 379
           + AL  A++   +  + +  +V  ++GR
Sbjct: 293 ASAL-LAVREYLKANEVDGPVVAVITGR 319


>UniRef50_D1CDZ3 Pyridoxal-5'-phosphate-dependent protein beta subunit n=1
           Tax=Thermobaculum terrenum ATCC BAA-798
           RepID=D1CDZ3_THET1
          Length = 353

 Score = 86.5 bits (213), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 71/351 (20%), Positives = 120/351 (34%), Gaps = 45/351 (12%)

Query: 44  QFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK 103
           +  D +  Y  R T L +   ++      +YLK E     GA K      + L      K
Sbjct: 27  EARDRISPYIER-TPLKESHTLSNRLGAKVYLKLEMFQTTGAFKIRGAFNKMLSLSPEEK 85

Query: 104 TEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGS 163
              +     G H  A A A++ LG+K  ++M     E            GA+V+      
Sbjct: 86  NRGVVAVSGGNHAQAVAYAASKLGIKATVFMARNTPENYIEAT---EHYGAQVV------ 136

Query: 164 ATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYP-TIVREFQRMIGEETKAQILEREGR 222
             L     EA +  +        M+      HPY    V   Q  IG E    + +    
Sbjct: 137 --LTSDIAEAFKLAAERQAYGEVMI------HPYADNQVMAGQGTIGLEILEDLPQVT-- 186

Query: 223 LPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGM 282
             D +I+  GGG  +    A    + +V + GVE  G           L+ G       +
Sbjct: 187 --DVIISIGGGGLISGVATAIKSQKPHVRIWGVETAG----ADSMSQALRAGHPIELPAI 240

Query: 283 KAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVS-ITDDEALEAFKTLCL 341
                           SI+  L  PSV  ++    +    + V+ ++D EA +A + L  
Sbjct: 241 T---------------SIAKTLGAPSVS-ENTLAITRKLVESVTVVSDKEAFQALEFLLE 284

Query: 342 HEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGR-GDKDIFTVHDIL 391
              ++    +S  LA A ++      +  L+++   G     D+     + 
Sbjct: 285 RAKVLTEPAASCTLAAAERLRSAFTPQSTLVLLLCGGNVSLADLCHYRQMF 335


>UniRef50_Q2SSZ6 Threonine dehydratase n=3 Tax=Mycoplasma mycoides group
           RepID=Q2SSZ6_MYCCT
          Length = 408

 Score = 86.1 bits (212), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 80/346 (23%), Positives = 122/346 (35%), Gaps = 60/346 (17%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T L     ++A T   +YLK E+L   G+ K      +        K   I    AG H 
Sbjct: 24  TPLHYADKLSALTGNNIYLKLENLQKTGSFKLRGATNKINKLTNEEKKHGIIAASAGNHA 83

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD 176
              A A+  LGLK  I M       +          G +V  V SG     DA  +A+  
Sbjct: 84  QGVAFAATNLGLKSTIVMPENAPMAKIQAT---EKYGGKV--VLSGR-FFDDALAKAIE- 136

Query: 177 WSGSYETAHYMLGTAAGPHPYPTI-VREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
                E    +       H +  I + + Q  I  E   QI        D  +  +GGG 
Sbjct: 137 -LKEKENLTLI-------HAFDDIEIIKGQATIAYEIDQQIKNI-----DYCLVPIGGGG 183

Query: 236 NAIGMFADFIN--ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQ 293
              G+   ++     N+ +IGVE     + + +    L             P+M      
Sbjct: 184 LMSGIAT-YLKQVNPNIKMIGVEAA--NVNSYQQAKALSR-----------PVMIDSK-- 227

Query: 294 IEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCL-----HEGIIPA 348
                SI+ G+    V      + +    D V ++++E  EA   L        EG    
Sbjct: 228 ----PSIADGIAVKKVSDLTFSILNQYVDDVVVVSEEEIAEAMLFLMENCKFVTEG---- 279

Query: 349 LESSHALAHAL---KMMRENPDKEQLLVVNLSGRGDKDIFTVHDIL 391
             S    A AL   K+  +N +K  + +V  SG G+ DI  V +I+
Sbjct: 280 --SGAVTAAALMFDKLNIKNQNKTIVGLV--SG-GNIDIAMVGNII 320


>UniRef50_C6A508 Probable threonine synthase n=1 Tax=Thermococcus sibiricus MM 739
           RepID=C6A508_THESM
          Length = 392

 Score = 86.1 bits (212), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 72/338 (21%), Positives = 128/338 (37%), Gaps = 31/338 (9%)

Query: 57  TALTKCQNITAGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           T L + +N+        LY+K E     GA K      +   A      +++  +  G  
Sbjct: 83  TRLYRMKNLEKKLGFGKLYIKNEGENPTGAFKDRGSSVEITKALEFHARKVVVAS-TGNM 141

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
             + +   +  GL+  I +       +        + GA++        T  +A  E+ R
Sbjct: 142 AASISAYGSKAGLEVTIVVPEGTPIGKLVQAV---VYGAKI---KIHGTTYDEALAESER 195

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
               + E  +Y+ G             E Q+  G E   Q+       PD ++  +G G+
Sbjct: 196 ---MAKEEDYYLTGN-------YHYRVEGQKSTGFEIFDQLR---FDSPDWIVVPIGAGT 242

Query: 236 NAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIE 295
           +   ++        VGLI   P   G++   + A +K  + G+      P+   ++ +  
Sbjct: 243 HLRAIWKAAKEFYKVGLIERLPKIAGVQVEGYDAIVKAWKEGM------PIKPRKEKKPT 296

Query: 296 ESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHAL 355
            + +I+            A   S G      +T++EA+ A   L   EG+     SS AL
Sbjct: 297 VASAIAVKAPVDGENVLRAIEESKGHLG--VVTNEEAMNAGLLLGK-EGLFVEPSSSTAL 353

Query: 356 AHALKMMREN-PDKEQLLVVNLSGRGDKDIFTVHDILK 392
           A A +M  E   DK++ +VV  +G G KD  T    +K
Sbjct: 354 ALARQMREEGIIDKDERIVVIATGHGLKDTKTWESFIK 391


>UniRef50_C9M5D2 Threonine synthase n=1 Tax=Jonquetella anthropi E3_33 E1
           RepID=C9M5D2_9BACT
          Length = 380

 Score = 86.1 bits (212), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 83/377 (22%), Positives = 138/377 (36%), Gaps = 52/377 (13%)

Query: 32  FVSAQK-DPEFQAQFNDLLKNYAGRPTALTK---CQNITAGT---------NTTLYLKRE 78
           F  A   DPE  ++ +D    Y GR   L        +  G            T++ K +
Sbjct: 30  FEQALSFDPEQLSRRHDGFWKY-GRALGLRHPEKAARLGEGQTPLLPLEWDGRTVFWKLD 88

Query: 79  DLLHGGAHKTN-QVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAK 137
            LL  G++K     +  A LA   G+ EI+ E  +G  G + A   A  G+ C +++ A 
Sbjct: 89  FLLPTGSYKDRGTAVMAASLA-ETGRREIV-EDSSGNAGSSLAAYCAASGITCHVFVPAS 146

Query: 138 DVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD---WSGSYETAHYMLGTAAGP 194
             E +     ++   GA +  V  GS     A   A+ +   +S       + LG     
Sbjct: 147 TSEGKC---LQIGSYGAHIHRVP-GSREDTTAAAVAMGETHFYSSHNWNPWFALG----- 197

Query: 195 HPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIG 254
                 VR +      E   Q+     R PDAV+   G GS  IG F  F      G I 
Sbjct: 198 ------VRTW----ALEAWEQMDF---RAPDAVVVPAGQGSLVIGAFRAFQELAACGAIS 244

Query: 255 VEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHA 314
             P  + ++  E  APL         G   P    +     E  + +  +         A
Sbjct: 245 RMPRIYAVQAAE-CAPLAE---AFDRGEDEPAAIEKGHTFAEGIASAEPVR--GFQVIQA 298

Query: 315 YLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENP-DKEQLLV 373
              + GR  +V + + +    FK+L    G+     S+       ++++E      ++ +
Sbjct: 299 VRETGGR--FVRVNNGQIAAGFKSLARR-GLFVEPTSAVVAPALSELIKEGQILPNEITL 355

Query: 374 VNLSGRGDKDIFTVHDI 390
             LSG G K +  + ++
Sbjct: 356 TLLSGTGLKAVDHLAEL 372


>UniRef50_A9BIT3 Threonine synthase n=4 Tax=Bacteria RepID=A9BIT3_PETMO
          Length = 421

 Score = 86.1 bits (212), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 69/343 (20%), Positives = 120/343 (34%), Gaps = 42/343 (12%)

Query: 57  TALTKCQNITAGTNTT-LYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           T L K   +        LY+K + L   G+ K        + A+  G   I+A    G  
Sbjct: 88  TPLYKSDVMAKLLGIETLYIKDDGLNPTGSLKDRASAIAVVKAQEAGM-NIVACASTGNA 146

Query: 116 GVASALASALLG--LKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
             + A   A +G  +K  I++ ++    +   V ++ + GA V+ V            +A
Sbjct: 147 ASSLAGNIASMGNEMKAVIFVPSRAPIGK---VTQLLVFGALVLSVKGSYEETFYLSQQA 203

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
           +  W        Y    A  P+     + E ++    E   Q+      + D ++  VG 
Sbjct: 204 IDKW------GWYNRNAAINPY-----LVEGKKTSSIEIAEQL---NWEMVDWLVYSVGD 249

Query: 234 GSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQ 293
           G    G +    +   +G I   P   G+++ E  AP+                   D  
Sbjct: 250 GCTIAGAWKGMYDLKQIGFIDKLPRLLGVQS-EGCAPITQA-----------FKSDTDLV 297

Query: 294 IEESYSISAGLDFPSVGPQHAYLNSTGRA-----DYVSITDDEALEAFKTLCLHEGIIPA 348
                +I+   D  +VG    Y+ +         D +++TDDE L   K L  + GI   
Sbjct: 298 PVPENTIA---DSIAVGKPRNYIKAIKAVKDSNGDMINVTDDEILNMIKILGKNTGIFGE 354

Query: 349 LESSHALAHALKMMRENPDK-EQLLVVNLSGRGDKDIFTVHDI 390
                 +A   K +     K  + + V ++G G KDI      
Sbjct: 355 PAGVAGVAGIKKAVENGIIKPSESVAVVVTGNGLKDIKNAEKA 397


>UniRef50_C8W164 Cysteine synthase n=3 Tax=cellular organisms RepID=C8W164_DESAS
          Length = 318

 Score = 85.7 bits (211), Expect = 3e-15,   Method: Composition-based stats.
 Identities = 64/335 (19%), Positives = 112/335 (33%), Gaps = 59/335 (17%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG---KTEIIAETGAG 113
           T + +   +    N  +Y K E    GG+ K    L     A+  G   + + I E  +G
Sbjct: 13  TPMIRINRLNPNPNVEIYAKFEGTNPGGSIKDRIALKMIEQAEAEGVLNRKKTIIEATSG 72

Query: 114 QHGVASALASALLGLKCRIYMG-AKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNE 172
             G+A A+  A+   K  I M  A  +ER+      ++  GA+VI       T  D    
Sbjct: 73  NTGIALAMIGAVKDYKVEIVMSEAVSIERRKM----IQAFGAKVILTDPEFGT--DGAIL 126

Query: 173 ALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVG 232
            +R     Y   ++        +           +  EE      +  GR+ D  ++ +G
Sbjct: 127 KVRKLLEQYPDRYFCTDQFTNKYNK----LAHSEITAEEI---WFQTNGRV-DYFVSGLG 178

Query: 233 GGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTED 291
                +G+ A        + +I  EP       G                     ++   
Sbjct: 179 TSGTLMGVGAGLKKYNPKIKIISAEPVAGHYIQG---------------------LKNLQ 217

Query: 292 GQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALES 351
             I       A LD                 + + I  +EA E  + +   EGI   + S
Sbjct: 218 EAIVPGIYNEAELD-----------------EIIMIETEEAFEMARQIVRKEGIFVGMSS 260

Query: 352 SHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFT 386
             ++  A+K+ R+      ++V     RG+K + T
Sbjct: 261 GASMLGAVKIARKLSSG--VIVTIFPDRGEKYLST 293


>UniRef50_C6A2V6 Threonine dehydratase n=1 Tax=Thermococcus sibiricus MM 739
           RepID=C6A2V6_THESM
          Length = 321

 Score = 84.6 bits (208), Expect = 5e-15,   Method: Composition-based stats.
 Identities = 76/335 (22%), Positives = 134/335 (40%), Gaps = 49/335 (14%)

Query: 49  LKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIA 108
           +++Y  R T L     ++   N  +YLK E+    G+ K   V  + L      K   I 
Sbjct: 15  IRDYI-RETPLDYSPFLSQKGNANVYLKLENFQLTGSFKIRGVFNKLLSLSEEEKKRGIV 73

Query: 109 ETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKD 168
              +G HG A A AS  L L   +++           +  ++     V     G+ T+K 
Sbjct: 74  TASSGNHGAAFAYASNFLNLNGIVFLPE---NASPAKIQDIKQY--NVELRFYGNDTVKT 128

Query: 169 ACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVI 228
                 R+++   E  +        P+  P  V   Q  IG E + Q+ +      DAV+
Sbjct: 129 EIFA--RNFAEEQEMIY------VPPYNDPK-VIGGQGTIGVELEKQLGKI-----DAVL 174

Query: 229 ACVGGGSNAIGMFADFINE--TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPM 286
             VGGG    G+   ++ E   +V +IGV+P        E+ A +       Y+ +KA  
Sbjct: 175 VPVGGGGLISGIA-GYLKEKMKDVEIIGVQP--------ENSAVM-------YYSIKAGK 218

Query: 287 MQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKT-LCLHEGI 345
           +   + +   +   + G++  S+  +          D++ ++++E  E+    L  H  +
Sbjct: 219 ILELESKPTLADGTAGGIEKDSITFELCRKYVD---DFILLSEEEIAESILLMLEKHHML 275

Query: 346 IPALESSHALAHA--LKMMRENPDKEQLLVVNLSG 378
           I   E + AL+ A  LK       K  +L+  LSG
Sbjct: 276 I---EGAAALSVAAYLKEAPRFKGKNVVLI--LSG 305


>UniRef50_A7I331 Threonine dehydratase n=54 Tax=Bacteria RepID=A7I331_CAMHC
          Length = 537

 Score = 83.8 bits (206), Expect = 1e-14,   Method: Composition-based stats.
 Identities = 48/209 (22%), Positives = 76/209 (36%), Gaps = 26/209 (12%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T+      ++      +YLK+E+L   GA+K      +        K   +    AG H 
Sbjct: 155 TSCDLAPKLSEIYGAKIYLKKENLQTTGAYKIRGAFNKIAHLSEDDKKRGVVAASAGNHA 214

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLK-DACNEALR 175
              A+++   G+K  I M           V   + +GAEVI        LK D  +EA  
Sbjct: 215 QGVAISAKHFGVKATIVMPEATP---LLKVAGTKSLGAEVI--------LKGDNFDEAY- 262

Query: 176 DWSGSYETAHYMLGTAAGPHPYPT-IVREFQRMIGEETKAQILEREGRLPDAVIACVGGG 234
            ++  Y   H  +      HP+    V+  Q  I  E    + +      D V+  VGGG
Sbjct: 263 AYALKYTKEHDKI----FVHPFDDEFVQAGQGTIALEMLESVPDL-----DYVVLPVGGG 313

Query: 235 SNAIGMFADFIN--ETNVGLIGVEPGGHG 261
               G+ + +I        +I V   G  
Sbjct: 314 GLISGVAS-YIKQVNPECKVIAVGAKGAP 341


>UniRef50_B5FEL5 Threonine synthase n=2 Tax=Vibrio fischeri RepID=B5FEL5_VIBFM
          Length = 376

 Score = 83.8 bits (206), Expect = 1e-14,   Method: Composition-based stats.
 Identities = 72/381 (18%), Positives = 133/381 (34%), Gaps = 47/381 (12%)

Query: 18  PQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKR 77
           PQ        +E  F   +    F  + +D+   +    T L +       +   + +K 
Sbjct: 31  PQTSFSKKDLIENEFTPRRYSSAFPVKKDDINITFNEAITPLCQA----EISGNPILVKL 86

Query: 78  EDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAK 137
           + L   G+ K              G T I AE  +G  G A A  +A   ++C I++ A 
Sbjct: 87  DSLQPTGSFKDRGASLVINYLNNHGITSI-AEDSSGNGGSAYAGYAAKGKMQCNIFVPAG 145

Query: 138 DVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPY 197
             + +     + RL GA  I V      +  A   A+         +HY      G + +
Sbjct: 146 TSKGK---TTQTRLYGANCIEVEGAREDVALA---AIESSVTH--GSHY-----VGHNWH 192

Query: 198 PTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEP 257
           P  +   +  I  E   Q   +    PD  +   G GS   G +  F      G I   P
Sbjct: 193 PLFIEGVKS-IAYEIWEQCRYKA---PDNFVVPAGNGSLLAGAYIGFSELLKGGEISKLP 248

Query: 258 GGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDG---QIEESYSISAGL---DFPSVGP 311
              GI++                    P +QT +     I    +I+ G+       +  
Sbjct: 249 RLFGIQSESIQ----------------PFVQTFNNKEINITSENTIAEGIKIKRSSRMNE 292

Query: 312 QHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQL 371
              ++  T   +++S+++ +   A K +   +G      S+ A A   ++++    K   
Sbjct: 293 IVQFVKETN-GNFISVSEQQIQSALKEMG-AQGYFIEPTSATAFAGIAQLIKTQEIKPDE 350

Query: 372 LVVN-LSGRGDKDIFTVHDIL 391
           L V  ++G G K   ++  ++
Sbjct: 351 LTVGVVTGNGLKATNSIEHLI 371


>UniRef50_A7IFG1 Pyridoxal-5'-phosphate-dependent protein beta subunit n=2
           Tax=Rhizobiales RepID=A7IFG1_XANP2
          Length = 340

 Score = 83.0 bits (204), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 70/334 (20%), Positives = 107/334 (32%), Gaps = 39/334 (11%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T L +   I A     + +K E L H G+ K      +  L     +   I    +G H 
Sbjct: 39  TPLFENAAINAACGARILIKPEMLQHTGSFKFRGASNRVALMSAAERAGGIVAWSSGNHA 98

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD 176
           +A +  +A  G+K  I M +     +   V     +G  V         L D   E   +
Sbjct: 99  LAISAVAARHGIKATILMPSDAPRAK---VEGAERLGGTV--------RLYDRATEVREE 147

Query: 177 WSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSN 236
                       G    P      V   Q  +G E   Q      +L  A+ AC GGG  
Sbjct: 148 IGADIAAR---TGAVIIPPYDDPHVIAGQGTVGLELAEQAAALGAQLDMALFACSGGGL- 203

Query: 237 AIGMFADFINETNVGLI-GVEPGGHGIETGEHGAPLKHGRV-GIYFGMKAPMMQTEDGQI 294
             G        +   L+   EP G      +    L  G+      G         D  +
Sbjct: 204 VAGAATALKARSPATLVYSAEPAGF----DDTARSLASGKPERNAPGATTLC----DALM 255

Query: 295 EESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHA 354
             +      L F    P +  L + G    V++TDDE   A + +     ++   E    
Sbjct: 256 VPTP---GLLTF----PINRALLAGG----VAVTDDEVKAAMRLVYDTLKLVV--EPGGV 302

Query: 355 LAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVH 388
              A  +  +   K + + V LSG G+ D  T  
Sbjct: 303 TPLAAVLAGKVDAKGKTVGVVLSG-GNVDPDTYA 335


>UniRef50_Q04513 Threonine dehydratase biosynthetic n=34 Tax=Actinomycetales
           RepID=THD1_CORGL
          Length = 436

 Score = 83.0 bits (204), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 73/341 (21%), Positives = 127/341 (37%), Gaps = 38/341 (11%)

Query: 56  PTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQ-ALLAKRMGKTEIIAETGAGQ 114
           PT L  C  ++  T   +YLKREDL    ++K    L   A L +      I+A + AG 
Sbjct: 39  PTPLQYCPRLSEETGAEIYLKREDLQDVRSYKIRGALNSGAQLTQEQRDAGIVAAS-AGN 97

Query: 115 HGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEAL 174
           H    A     LG++ RIY+  +  +++     R+ + G E +       +L    N   
Sbjct: 98  HAQGVAYVCKSLGVQGRIYVPVQTPKQK---RDRIMVHGGEFV-------SLVVTGNNFD 147

Query: 175 RDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGG 234
              + ++E A     T   P      V   Q  +  E  +Q+    G+  D V+  VGG 
Sbjct: 148 EASAAAHEDAERTGATLIEPFDARNTVI-GQGTVAAEILSQLTSM-GKSADHVMVPVGG- 204

Query: 235 SNAIGMFADFINETNVG--LIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDG 292
              +     ++ +      ++G+EP G         A L +G       +   +    DG
Sbjct: 205 GGLLAGVVSYMADMAPRTAIVGIEPAG----AASMQAALHNGGPITLETVDPFV----DG 256

Query: 293 QIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESS 352
              +       L++  V        + GR   +S T+         L  +EGII     +
Sbjct: 257 AAVKR---VGDLNYTIVE------KNQGRVHMMSATEGAVCTEMLDLYQNEGIIAEPAGA 307

Query: 353 HALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
            ++A      +E       +VV +   G+ D+    +I + 
Sbjct: 308 LSIAGL----KEMSFAPGSVVVCIISGGNNDVLRYAEIAER 344


>UniRef50_Q4LEC5 Threonine synthase n=1 Tax=uncultured crenarchaeote 10-H-08
           RepID=Q4LEC5_9CREN
          Length = 414

 Score = 82.7 bits (203), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 67/333 (20%), Positives = 120/333 (36%), Gaps = 37/333 (11%)

Query: 57  TALTKCQNITAGTNTT-LYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           T L   Q +        L+LK E      + K   +   A  A  MG+ +++  + +G  
Sbjct: 80  TPLLHAQRLGGELGVKRLFLKDETRNPTASFKDRAMAVGAAKAVEMGRRDVVIAS-SGNA 138

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVI---PVHSGSATLKDACNE 172
             + A  SA LGL+C  ++       ++  +    L GA V+    V  G     D   +
Sbjct: 139 ASSLAAYSASLGLRCTAFVPEDVAMGKASQLL---LYGARVLRVKQVEEGRDPTVDLMMQ 195

Query: 173 ALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVG 232
            +++         Y   +     P+     E  + I  E   Q+      +PD V    G
Sbjct: 196 TVKEL------GWYPCPSF---GPFNPYQVEGPKTIVYEMVEQM---GWGVPDFVFIPTG 243

Query: 233 GGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDG 292
            G  A G++        +GLI   P    ++   +   +      I  G +   ++ E  
Sbjct: 244 SGCLATGIWKALKELRLLGLIESYPKLVPVQPSGNMPLV----RAILQGKRFEEVEPEKW 299

Query: 293 QIEESYSISAGL--DFP--SVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPA 348
                 SI++GL   +P            + G    V++ +DE  EA K L   EG+   
Sbjct: 300 ----PKSIASGLLDPYPWDGDAAMEGVRTTGG--TAVAVEEDEIREAVKKLARLEGVFAE 353

Query: 349 LESSHALAHALKMMREN---PDKEQLLVVNLSG 378
              +  +A   K++ +         +++V  SG
Sbjct: 354 PSGAVGVAAVQKLLEQGVVEASDTVVVLVTASG 386


>UniRef50_B9Z0N9 Pyridoxal-5'-phosphate-dependent protein beta subunit n=1
           Tax=Lutiella nitroferrum 2002 RepID=B9Z0N9_9NEIS
          Length = 353

 Score = 82.7 bits (203), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 69/348 (19%), Positives = 114/348 (32%), Gaps = 70/348 (20%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEI---IAETGAG 113
           T +     +    +  +++K E L   G+ K    L + L    M   ++   +    AG
Sbjct: 50  TPVLNSPMLDGLNDCRIFVKAESLQLTGSFKIRGALNKIL---SMDPKDLHGGVLTYSAG 106

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVI---PVHSGSATLKDAC 170
            HG A A  + L+G    + +       +  N    R  GAE++   PV           
Sbjct: 107 NHGQAVAAGAKLVGCPVVVVLPNTAPAIKVEN---CRWWGAEIVLYDPVTQMRE------ 157

Query: 171 NEALRDWSGSYETAHYMLGTAAGPHPYPTI-VREFQRMIGEETKAQILEREGRLPDAVI- 228
            E + + +                 P+    V   Q  +G E   Q+ E  G  PDAV+ 
Sbjct: 158 -EVMDEIARQRGMTF--------ISPFDDFDVMAGQGTVGLELCEQMKEL-GEEPDAVVI 207

Query: 229 ACVGGG--SNAIGMFADFINETN---VGLIGVEPGGHGIETG---EHGAPLK--HGRVGI 278
            C GGG  S  +   + +  +     V + G E   + I TG       PL    G  G 
Sbjct: 208 NCSGGGLASGVVTAVSAYYPKAEFYIVEINGAEKMANSIMTGAPQRVTPPLTVMDGIAGP 267

Query: 279 YFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKT 338
             G +                              + L        +S  D+EAL A   
Sbjct: 268 VAGNRT----------------------------LSVLMQHK-VKCLSTNDEEALGAVSA 298

Query: 339 LCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFT 386
                 ++     + +LA  L   + +   + + V+   G  D DIF+
Sbjct: 299 AFRMLKLVVEPGGAASLAAVLS-KKSHWTGKNIAVICSGGNADPDIFS 345


>UniRef50_Q1I705 Threonine synthase n=2 Tax=Pseudomonas RepID=Q1I705_PSEE4
          Length = 414

 Score = 82.7 bits (203), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 71/336 (21%), Positives = 124/336 (36%), Gaps = 34/336 (10%)

Query: 57  TALT-KCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEI-IAETGAGQ 114
           T L  +   +   +   +++K E     G+ K         LA   G + + +A TG   
Sbjct: 86  TPLYERPGLLETDSGMRVWVKDESRQPTGSLKDRASALAVALALESGASTVAVASTGNA- 144

Query: 115 HGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEAL 174
              A A  SA  GL+  I++       +     +M   GAEVI V         A +EA 
Sbjct: 145 -ASALAGMSAERGLRNVIFIPRTTPREKL---AQMIGYGAEVILVDG-------AYDEAF 193

Query: 175 RDWSGSYE-TAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
                + E    Y   T    +     + E ++ +  E   Q+     ++PD V   VG 
Sbjct: 194 EQCRNACESNGWYNRTTGINSY-----MTEGKKTVAFEICEQL---GWQVPDLVFVPVGN 245

Query: 234 GSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQ 293
           G     +   F +   +G I   P   G++  +     +    G+      P+ Q E   
Sbjct: 246 GCILGAVHKGFQDLLKLGWIERMPRLMGVQARDSNFMYRAWSSGL------PLEQVEKRA 299

Query: 294 IEESYSISAGLDFP--SVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALES 351
                S S  + FP   +    A  +S G  +++ + D   ++A   L    GI P   +
Sbjct: 300 PTSLAS-SINVAFPRDRLKALRAVRDSEG--EFLCVDDTAIVQAASRLAARTGIFPEAGA 356

Query: 352 SHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTV 387
           + + A  L+   ++P   +  V+ ++G G KD    
Sbjct: 357 ASSYAGLLQYAEQHPHSRESAVLLITGSGLKDTSIY 392


>UniRef50_D0LAQ5 Threonine dehydratase n=6 Tax=Actinomycetales RepID=D0LAQ5_GORB4
          Length = 457

 Score = 82.3 bits (202), Expect = 3e-14,   Method: Composition-based stats.
 Identities = 86/404 (21%), Positives = 146/404 (36%), Gaps = 71/404 (17%)

Query: 18  PQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKR 77
           P+ +     +L    + A            L    A   T L  C  I+A T   ++LKR
Sbjct: 5   PETVPEHPSELTADAIEA----------ASLRIAPAVIRTPLEACPRISASTGAQIHLKR 54

Query: 78  EDLLHGGAHKTN---QVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYM 134
           EDL    ++K      V+ Q  L++      ++A + AG H    A A   +G+  RIY+
Sbjct: 55  EDLQSVRSYKIRGAYNVMAQ--LSRSELDRGVVAAS-AGNHAQGVAYACRTMGVHGRIYV 111

Query: 135 GAKDVERQSPNVFRMRLMGAEVIPV-------HSGSATLKDACNEALRDWSGSYETAHYM 187
                +++     R+   G E + +        + +A  +         W  +++     
Sbjct: 112 PTTTPKQK---RDRISWHGGEFVELLAVGDTYDAAAAAAQADVLRTGATWIHAFDDPRTA 168

Query: 188 LGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADF-IN 246
            G               Q  I  E   Q+    GR+PD V+A VGGG    GM   F   
Sbjct: 169 AG---------------QGTIAFEIVDQL----GRVPDVVVAPVGGGGCLAGMVTYFRAR 209

Query: 247 ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEES-YSISAGL- 304
             +V ++GVEP G    T    A L HG       +   +      +I    + + AG+ 
Sbjct: 210 RPDVAIVGVEPTGAISLT----AALVHGGPYTLPTIDPFVDGAAVKRIGSIGHGVLAGMG 265

Query: 305 ----DFPSVG--PQHAYLN---------STGRADYVSITDDEALEAFKTLCLHEGIIPAL 349
               D P++   P H+              G      + +     A   L  +EGII   
Sbjct: 266 AAVSDHPALAEVPVHSTTRVLTDDPIEVHAGTTHITHVDEGAICSAMLELYQNEGIIAEP 325

Query: 350 ESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
             + A+A   ++       +  +   +SG G+ D+    +I++ 
Sbjct: 326 AGALAVAALDRL---RLPADATVACLVSG-GNNDVSRYGEIIER 365


>UniRef50_B8J2I1 Cysteine synthase n=1 Tax=Desulfovibrio desulfuricans subsp.
           desulfuricans str. ATCC 27774 RepID=B8J2I1_DESDA
          Length = 306

 Score = 82.3 bits (202), Expect = 3e-14,   Method: Composition-based stats.
 Identities = 66/329 (20%), Positives = 125/329 (37%), Gaps = 56/329 (17%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE---IIAETGAG 113
           T + +   ++     T++LK E+   GG+ K          A + G+ E   ++ E  +G
Sbjct: 12  TPMLRLD-LSKDMPGTVWLKLENRNPGGSIKDRVAFHLIENALQWGELEPGGLVVEATSG 70

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
             G+  AL SA+ GL+C + M              +R +GAE++   + +  +  A  EA
Sbjct: 71  NMGIGIALVSAVRGLRCVLAMPES---MSLERRNLLRGLGAELVLTPA-ARGMTGAVEEA 126

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
            R    + E   ++ G        P  V+   +  G E      +  G++ D ++A VG 
Sbjct: 127 RR---IAEEQGGFIPG----QFTNPEAVQAHYKTTGPEI---YSDSVGKM-DVLVAGVGS 175

Query: 234 GSNAIGMFADFINE--TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTED 291
           GS+  G    F+ E      +I VEP    + +G   +P               ++Q   
Sbjct: 176 GSSITG-AGRFLKERIPGFRVIAVEPAASPVISGGAASP--------------HLIQGIG 220

Query: 292 GQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALES 351
                                 A L+ +   + +    +EAL+  + L   +GI+  + +
Sbjct: 221 AGFIP-----------------AILDRSLLDEILLADGEEALDTARLLMR-QGIVAGIST 262

Query: 352 SHALAHALKMM--RENPDKEQLLVVNLSG 378
              +  AL++   +E   K  +     +G
Sbjct: 263 GANVRAALQVAARQEMAGKNIVTFACDTG 291


>UniRef50_Q6C6D8 YALI0E10307p n=1 Tax=Yarrowia lipolytica RepID=Q6C6D8_YARLI
          Length = 329

 Score = 81.9 bits (201), Expect = 3e-14,   Method: Composition-based stats.
 Identities = 81/360 (22%), Positives = 128/360 (35%), Gaps = 58/360 (16%)

Query: 55  RP----TALTKCQNITAGTNTTLYLKREDLLHGGAHK-------TNQVL---GQALLAKR 100
           RP    T L K    +      +YLK E+L   G+ K        +  L    QA L   
Sbjct: 2   RPGYIETPLLKNDIFSHQVGCNVYLKMENLQPSGSFKSRGMTQVISDALDSDPQASL--- 58

Query: 101 MGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVH 160
              T  +  +  G  G+A+A+ S L G+ C + +       +   V ++R  GAEVI   
Sbjct: 59  --DTLHVCSSSGGNAGLAAAVTSRLNGVACTVVVPEST---KPRMVEKLRAAGAEVI--- 110

Query: 161 SGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPT-IVREFQRMIGEETKAQILER 219
                  +A +   ++     E       T    HP+    V +    + +E   Q    
Sbjct: 111 VHGKHWSEANDFLQKEEMPRLEKTG---KTPIYCHPFDAPAVWKGNSTLIDEIIKQ---- 163

Query: 220 EGRLPDAVIACVGGGSNAIGMFADFINET-NVGLIGVEPGGHGIETGEHGAPLKHGRVGI 278
            G  PDAV+  VGGG    G+         N  +I VE  G           L+ G    
Sbjct: 164 -GITPDAVVCSVGGGGLFNGVVEGLKRHKLNCPVIVVETNG----ADALSRSLQKGEQVT 218

Query: 279 YFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKT 338
             G+ + +  +         +      +P+V    +              DD+A+ A   
Sbjct: 219 LPGITS-IATSLGAVRVADKTFENAQTYPTVSAVVS--------------DDDAVSALVE 263

Query: 339 LCLHEGII--PALESSHALAHALKMMRENPDKEQLLVV--NLSGRGDKDIFTVHDILKAR 394
               + II  PA  +S A+  ALK + +      ++VV    S  G  DI      L+A+
Sbjct: 264 YAETKQIIVEPACGASLAVLPALKDLVDLKPDSNVVVVLCGGSATGISDIAQFKKDLEAK 323


>UniRef50_A3DLF6 Cysteine synthase n=2 Tax=Desulfurococcaceae RepID=A3DLF6_STAMF
          Length = 338

 Score = 81.9 bits (201), Expect = 4e-14,   Method: Composition-based stats.
 Identities = 66/335 (19%), Positives = 121/335 (36%), Gaps = 59/335 (17%)

Query: 57  TALTKCQNITAGTNTT--LYLKREDLLHGGAHKTNQVLGQALLAKRM-------GKTEII 107
           T + + Q I    N    ++ K E +   G+ K    +   ++ K M       G T ++
Sbjct: 16  TPIIRLQRIEKDQNVDFEIWAKAEFMNPTGSVKDR--MAYYMIKKAMDKGELKPGMTIVV 73

Query: 108 AETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLK 167
             TG    G++ +   +  GLK  I +     E  +     MRL GA+ +    G +   
Sbjct: 74  PTTG--NTGISFSALGSYFGLKVLIVIPE---EMSAERFMLMRLFGADFLFTPGGESDAG 128

Query: 168 DACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAV 227
            A   A +    + +  ++              V+      G+E   QI       PDA 
Sbjct: 129 TALETAKKLAEENPDKYYF-----FDQWSDEANVQAHYETTGKEILDQI-----GCPDAF 178

Query: 228 IACVGGGSNAIGMFADFINE-TNVGLIGVEPGGHGI-----ETGEHGAPLKHGRVGIYFG 281
           +A VG G   +G+      E  NV + G EP    +     +TG+ G   +H   G+  G
Sbjct: 179 VAQVGTGGTLMGVAKRLKEECKNVIVAGAEPAECPVAAYWFKTGKEGPWGRHEIEGVGDG 238

Query: 282 MKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCL 341
               +++                 +        +L      D+V+ T +EA+   + +  
Sbjct: 239 FVPDIVK----------------RY-------KHLLD----DFVTSTSEEAIMMARKIAR 271

Query: 342 HEGIIPALESSHALAHALKMMRENPDKEQLLVVNL 376
            E +   + S   +  A+K+ R +   +   VV +
Sbjct: 272 LEALPVGISSGANVVSAIKLGRSHGLGKGKKVVTI 306


>UniRef50_C6HUM2 Cysteine synthase n=1 Tax=Leptospirillum ferrodiazotrophum
           RepID=C6HUM2_9BACT
          Length = 316

 Score = 81.9 bits (201), Expect = 4e-14,   Method: Composition-based stats.
 Identities = 71/329 (21%), Positives = 112/329 (34%), Gaps = 63/329 (19%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHK-------TNQVLGQALLAKRMGKTEIIAE 109
           T L     I+     T+ +K E    GG+ K             + LLA R      I E
Sbjct: 23  TPLVPLSGISFDLGRTILVKLESKNLGGSIKDRPALFMIEDARARGLLAPRA----PIVE 78

Query: 110 TGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDA 169
             +G  G+  A    L      I M     +     V  +R +GA V    + +  +  A
Sbjct: 79  ATSGNMGIGLAQIGVLAHHPVTIVMPEGMSQE---RVSHLRALGATVELTPA-AGGMSAA 134

Query: 170 CNEALRDWSGSYETAHYMLGTAAGPHPY--PTIVREFQRMIGEETKAQILEREGRLPDAV 227
              A  +   S   A         P  +  P       R  G E    I+E  G +PD  
Sbjct: 135 IRRA-EEIVSSIHGAFM-------PRQFDNPANPDSHYRTTGPE----IVESLGGVPDGF 182

Query: 228 IACVGGGSNAIGMFADFINE--TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAP 285
           ++ VG G    G+   F+ E    + +  VEP    + +G  GAP  H   GI  G    
Sbjct: 183 VSGVGTGGTISGV-GRFLREKSPEIPVWAVEPESSPVLSG--GAPGPHRIQGIGAGFVPK 239

Query: 286 MMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGI 345
           ++                                 R    ++TD +A+E  + L   EGI
Sbjct: 240 ILD---------------------------RKVISRV--FTVTDIQAIETARRLAKEEGI 270

Query: 346 IPALESSHALAHALKMMRENPDKEQLLVV 374
           +  + S   +  A+ + R  P+  +++ V
Sbjct: 271 MAGISSGANVFAAIALARTLPEGSRVVTV 299


>UniRef50_C7MM05 Cysteine synthase n=1 Tax=Cryptobacterium curtum DSM 15641
           RepID=C7MM05_CRYCD
          Length = 317

 Score = 81.5 bits (200), Expect = 5e-14,   Method: Composition-based stats.
 Identities = 60/327 (18%), Positives = 106/327 (32%), Gaps = 46/327 (14%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK----TEIIAETGA 112
           T L + +  +      + +K E    G + K          A++ G+      ++ E  +
Sbjct: 14  TPLIELKRFSQQVQARVLVKYEAANPGASIKDRAARSMIERAEQRGEIEPGKSVLIEPTS 73

Query: 113 GQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNE 172
           G  G+  A+  A  G +  + M    + R+          GA++    +    ++ A + 
Sbjct: 74  GNTGIGIAMIGAARGYRVVLTMPE-SMSRE--RRALAAAYGAQLELTPAALG-MRGAVDR 129

Query: 173 ALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVG 232
           A    S          G   G    P      +     E + Q+    G  PD +IA VG
Sbjct: 130 AAELASQIEG------GWVVGQFTNPDNPLAHEVTTAPEIEQQL----GSAPDVLIAGVG 179

Query: 233 GGSNAIGMFADFINETNV-GLIGVEPGGHGI-ETGEHGAPLKHGRVGIYFGMKAPMMQTE 290
            G    G    F          GVEP    I      G  +  G  GI            
Sbjct: 180 TGGTISGCAHYFQQHKAPTRFFGVEPAESAIIAQALAGEDITPGPHGI------------ 227

Query: 291 DGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALE 350
             Q   +  I   LD        A L     A  +++    AL+  + +   EG++  + 
Sbjct: 228 --QGIGANFIPETLD-------LAVL-----AGAIAVPTAVALDYARRIAREEGLLVGIS 273

Query: 351 SSHALAHALKMMRENPDKEQLLVVNLS 377
           S   LA   ++++ +       +V  +
Sbjct: 274 SGANLAAVERLVQHDESARGKTIVTFA 300


>UniRef50_B9J9P9 Threonine dehydratase protein n=49 Tax=Alphaproteobacteria
           RepID=B9J9P9_AGRRK
          Length = 354

 Score = 81.5 bits (200), Expect = 5e-14,   Method: Composition-based stats.
 Identities = 76/361 (21%), Positives = 113/361 (31%), Gaps = 43/361 (11%)

Query: 32  FVSAQKDPEFQA----QFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHK 87
           F   + DP        +      +   R T L     +       L++K E L H G+ K
Sbjct: 23  FPQQKSDPSMVDIAMIEAARARIDGRARRTPLLSSPFLDEIAGRRLFVKAECLQHTGSFK 82

Query: 88  TNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVF 147
                      +   +   +    +G H    ALA+ L G+   I M +   + +  N  
Sbjct: 83  FRGGWSAVSALEPSVRARGVIAFSSGNHAQGVALAAQLHGIPAVIIMPSDAPKLKIANT- 141

Query: 148 RMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRM 207
             R +GAEV+        L D   E   +          +  T   P   P  V   Q  
Sbjct: 142 --RALGAEVV--------LYDRVKEDRDEIGARLSRERGL--TLIKPFDEPQ-VIAGQGT 188

Query: 208 IGEETKAQILEREGRLPDAVIACVGGG--SNAIGMFADFINETNVGLIGVEPGGHGIETG 265
            G E   Q  E        ++ C GGG  S              V     EP     +T 
Sbjct: 189 TGLEIAEQAAEEGIDTATVLVPCGGGGLTSGIALALEARAPGFKVR--PCEPKNFE-DTT 245

Query: 266 EHGAPLKHGRVGIYFGMKAPMMQT-EDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADY 324
                 +  R     G     + T + G I                P    L   G    
Sbjct: 246 RSLVSGQIERNAALQGSICDAIITPQPGNITF--------------PILKRLCGPGLV-- 289

Query: 325 VSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDI 384
             +TD+EAL+A +       I+     + ALA AL   +E  D + ++ V   G  D D+
Sbjct: 290 --VTDEEALDAMELAFKRLKIVVEPGGAVALAAALFHGKEI-DGDTVIAVTSGGNVDTDV 346

Query: 385 F 385
           F
Sbjct: 347 F 347


>UniRef50_Q3M387 L-threonine synthase n=107 Tax=cellular organisms
           RepID=Q3M387_ANAVT
          Length = 454

 Score = 81.5 bits (200), Expect = 5e-14,   Method: Composition-based stats.
 Identities = 71/343 (20%), Positives = 121/343 (35%), Gaps = 45/343 (13%)

Query: 57  TALTKCQNITAGTN-TTLYLKREDLL-HGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQ 114
           T L +   +        LY+K + +     + K   V      A+ +G T +   +  G 
Sbjct: 110 TPLVRSHRLARRLGLNKLYIKNDAVNMPTLSFKDRVVSVALSRARELGFTTVSCAS-TGN 168

Query: 115 HGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVI-PVHSGSATLKDACNEA 173
              ++A  +A  GL C +++ A D+E         +++G+ +  P         D  N  
Sbjct: 169 LANSTAAIAAHAGLDCCVFIPA-DLEAG-------KILGSLIYSPTLMAVKGNYDQVNRL 220

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
             + + ++      +       PY +   E  + +G E   Q+      LPD V+A +  
Sbjct: 221 CSEVANTHGWGFVNI----NLRPYYS---EGSKTLGFEVAEQL---GWELPDHVVAPLAS 270

Query: 234 GSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQ 293
           GS    ++  F     VGL+       G +    GA    G   I    K      ED  
Sbjct: 271 GSLFTKIYKGFQEFVEVGLV------EGKKVRFSGAQ-AEGCSPIAQAFK------EDRD 317

Query: 294 IEES-------YSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGII 346
             +         SI+ G     V        + G  +  S+ D E +E  K L   EGI 
Sbjct: 318 FIKPVKPNTIAKSIAIGNPADGVYAVDIAKKTGGNIE--SVNDAEIIEGIKLLAETEGIF 375

Query: 347 PALESSHALAHALKMMRENP-DKEQLLVVNLSGRGDKDIFTVH 388
                   +A   K++     D ++  VV ++G G K    V 
Sbjct: 376 TETAGGTTVAVLKKLVEAGKIDPDETTVVYITGNGLKTQEAVQ 418


>UniRef50_C9KLW2 Threonine synthase n=2 Tax=Veillonellaceae RepID=C9KLW2_9FIRM
          Length = 342

 Score = 81.5 bits (200), Expect = 5e-14,   Method: Composition-based stats.
 Identities = 66/310 (21%), Positives = 122/310 (39%), Gaps = 43/310 (13%)

Query: 75  LKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYM 134
           LK E LL  G+ K     G       +G  +I  ++ +G  G + A  +A   ++C +Y 
Sbjct: 73  LKMEHLLPTGSFKDRGACGMINALHDLGIKKIALDS-SGNAGASMAAYAAAADMECTVYT 131

Query: 135 GAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGP 194
              D+ ++   V ++   GA+++ V +G         +A      +   A+Y        
Sbjct: 132 P-DDISQEK--VKQIEAYGAKIVKVANGRM-------KACAAVKQNLGDAYYA------S 175

Query: 195 HPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVG-LI 253
           H Y  +  E  + +  E   Q+      +PD +   VG G+  IG+F  F+    +   +
Sbjct: 176 HVYNPLFFEGIKSMAHELYDQL---GHHVPDYIFMPVGNGTMLIGLFLGFMEIGRLPHFV 232

Query: 254 GVEPGGH-GIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQ 312
            V+      +    H  P    R  I   ++     T+  +++E                
Sbjct: 233 AVQSSKCAPLYEAYHEVPASPKRTTIAEAIR----ITKPKRLKE---------------M 273

Query: 313 HAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLL 372
              +  +G  D +++ D + L+A K L  H GI   + S+ ALA A++           +
Sbjct: 274 VKAIRDSG-GDVITVPDKDILKAQKYLS-HRGIYVEMTSAAALAGAVQFFENGKPDNYKV 331

Query: 373 VVNLSGRGDK 382
           V+ L+G G K
Sbjct: 332 VIPLTGNGLK 341


>UniRef50_A5CWZ8 Threonine dehydratase n=1 Tax=Candidatus Vesicomyosocius okutanii
           HA RepID=A5CWZ8_VESOH
          Length = 325

 Score = 81.1 bits (199), Expect = 7e-14,   Method: Composition-based stats.
 Identities = 50/213 (23%), Positives = 77/213 (36%), Gaps = 24/213 (11%)

Query: 55  RPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQA-LLAKRMGKTEIIAETGAG 113
           R T L     I+   +  +YLKREDL    + K      +   L  R     +I    AG
Sbjct: 18  RKTQLEFASQISMHLDNKIYLKREDLTPVHSFKLRGAYHKIRTLNIRQLSKGVIT-CSAG 76

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
            H    A ++  LG+   I M     + +  +V   + +GAEVI          ++ + A
Sbjct: 77  NHAQGVAFSAKKLGIYAVIVMPKITPKIKVDSV---KSLGAEVIL-------FGNSYDVA 126

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTI-VREFQRMIGEETKAQILEREGRLPDAVIACVG 232
                   +   Y        H +  + V   Q  I  E   Q+ +      D +   VG
Sbjct: 127 YDFSQNIAKKKGYTF-----IHAFDDLDVIAGQGTIAYELLEQLDDI-----DYIFVPVG 176

Query: 233 GGSNAIGMFADF-INETNVGLIGVEPGGHGIET 264
           GG    G+ +        + +IGVEP G    T
Sbjct: 177 GGGLITGIASVIKTQRPKIKIIGVEPVGSAAFT 209


>UniRef50_P74193 Threonine synthase n=364 Tax=cellular organisms RepID=THRC_SYNY3
          Length = 382

 Score = 81.1 bits (199), Expect = 7e-14,   Method: Composition-based stats.
 Identities = 66/339 (19%), Positives = 114/339 (33%), Gaps = 58/339 (17%)

Query: 57  TALTKCQNITAGTN--TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEII-AETGAG 113
           T L     I         +++K + L   G+ K   +      AK  G   +I A TG  
Sbjct: 61  TPLIPAPAIAKRIGKDVRVFVKYDGLNPTGSFKDRGMTMAISKAKEAGAKAVICASTG-- 118

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
               ++A A+       R ++   D       + +  + GAEVI +        D     
Sbjct: 119 --NTSAAAAAYARRAGLRAFVIIPDGYVALGKLGQALIYGAEVIAIDGNF----DDALTT 172

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
           +R  S  Y      L  +  P+       E Q+    E    I++  G+ PD +   VG 
Sbjct: 173 VRQLSEHYPVT---LVNSVNPYR-----LEGQKTAAFE----IVDVLGQAPDWLCIPVGN 220

Query: 234 GSNAIGMFADFI-------NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPM 286
             N    +  F         +    ++G +  G         AP   G+           
Sbjct: 221 AGNITAYWMGFCQYKELGKGDRLPRMMGFQAAG--------SAPFIQGQP---------- 262

Query: 287 MQTEDGQIEESYSISAGLDFPSVGPQHAYLN--STGRADYVSITDDEALEAFKTLCLHEG 344
                  I    +++  +   +                ++  +TD E LEA++ L   EG
Sbjct: 263 -------ISHPETLATAIRIGNPANWDKAWAASRESNGEFHPVTDAEILEAYRILAAEEG 315

Query: 345 IIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKD 383
           +     S+ ++A  LK   + P    ++ V L+G G KD
Sbjct: 316 VFCEPASAASVAGLLKQKDQVPAGATVVCV-LTGNGLKD 353


>UniRef50_B8P126 Predicted protein n=6 Tax=cellular organisms RepID=B8P126_POSPM
          Length = 509

 Score = 80.7 bits (198), Expect = 8e-14,   Method: Composition-based stats.
 Identities = 48/215 (22%), Positives = 83/215 (38%), Gaps = 20/215 (9%)

Query: 16  YVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYL 75
           + P+ L     +L +  +     P++             + T L  C N++A     ++L
Sbjct: 12  HAPEPLPYP--RLSKHHLLPSGTPDYLRLILTSKVYEVLKETPLFYCPNLSARFGNQIWL 69

Query: 76  KREDLLHGGAHKTNQVLG-QALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYM 134
           KREDL    + K        A +++      ++    AG H    AL+ + LG+ C I M
Sbjct: 70  KREDLQEVFSFKIRGAYNFMANISEEERWKGVVT-CSAGNHAQGVALSGSKLGIPCTIVM 128

Query: 135 GAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGP 194
                  +  NV R   +GA+V+             +EA  +      +AH ++     P
Sbjct: 129 PKGTPAIKVRNVSR---LGAKVVL-------YGQDFDEAKAE-CARLASAHGLI--FVPP 175

Query: 195 HPYPTIVREFQRMIGEETKAQILEREGRLPDAVIA 229
           +  P +V   Q  IG E   Q+ +      DA+ A
Sbjct: 176 YDDPLVVA-GQGTIGMEILKQMSDA--ETLDAIFA 207


>UniRef50_B7G9B5 L-threonine ammonia-lyase n=3 Tax=cellular organisms
           RepID=B7G9B5_PHATR
          Length = 606

 Score = 80.7 bits (198), Expect = 9e-14,   Method: Composition-based stats.
 Identities = 75/336 (22%), Positives = 119/336 (35%), Gaps = 49/336 (14%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETG----- 111
           + L   +N++A    T+ LKRED     + K           K    +  + + G     
Sbjct: 106 SELQHAKNLSAHLKNTVLLKREDTQPVFSFKIRGA-----YNKMSHLSRDLLDKGVVCCS 160

Query: 112 AGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACN 171
           AG H    AL++ +LG +  I M       +   V  +R+ G   + V        +A  
Sbjct: 161 AGNHAQGVALSAKMLGCRAVIVMPLATPAIK---VNAVRIHGGPSVEVRLFGNNYDEAAT 217

Query: 172 EALRDWSGSYETAHYMLGTAAGPHPYPT-IVREFQRMIGEETKAQILEREGRLPDAVIAC 230
           EA R      E     +      HP+   +V   Q  IG E    + E   R  DA+  C
Sbjct: 218 EAKRL---QLEDGMTFV------HPFDDPLVIAGQGTIGMEI---LKECVSRPLDAIFVC 265

Query: 231 VGGGSNAIGMFADFIN--ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQ 288
            GGG    G+ A ++      V +IGVE      +     A L+ G+          +  
Sbjct: 266 CGGGGMLAGIAA-YVKRVRPTVKVIGVEAA----DAAGMTASLREGK---------LVTL 311

Query: 289 TEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPA 348
              G   +  ++        VG +   +  T   D +++  DE   A K       ++  
Sbjct: 312 DSVGLFADGAAVRR------VGDETFRVCKTLVDDMITVDTDEICNAIKLTYNDARVVLE 365

Query: 349 LESSHALAHALKMMRENPDKEQLLVVNLSG-RGDKD 383
              + A+A   K +  N    Q LV   SG   D D
Sbjct: 366 PAGALAVAGMRKYVHTNELSGQTLVAITSGANMDFD 401


>UniRef50_D0N3C1 Cysteine synthase, putative n=1 Tax=Phytophthora infestans T30-4
           RepID=D0N3C1_PHYIN
          Length = 396

 Score = 80.3 bits (197), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 68/337 (20%), Positives = 115/337 (34%), Gaps = 43/337 (12%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE---IIAETGAG 113
           T L +  +++  T   +  K E L  GG+ K     G    A+R G  +    I E  +G
Sbjct: 60  TPLIELTSLSKATGCKILAKAELLNPGGSSKDRVAKGIVEDAERRGLLKEGGTIIEGTSG 119

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPV-HSGSATLKDACNE 172
             G++ +L +   G +C I M     + +S     +   GAEV+ V  +     K   NE
Sbjct: 120 STGISLSLMARARGYRCVIVMPDDQAKEKSQ---LLEQFGAEVVLVKPASIVNAKHYVNE 176

Query: 173 ALRDWSGSYETAHYMLGTAAGPHPYPTIVR--EFQRMIGEETKAQILEREGRLPDAVIAC 230
           A R  + + E  ++          +             G E   Q         DA +  
Sbjct: 177 AKRL-ARNTEGGYFT-------DQFENTANFDSHYATTGPEIWRQ----TNGSVDAFVMA 224

Query: 231 VGGGSNAIGMFADFINE--TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQ 288
            G G    G  + ++ E   NV +   +P G  +                         Q
Sbjct: 225 AGTGGTIAGT-SAYLKEQNPNVQVFLADPPGSSLYNKVRS-------------NVCYAPQ 270

Query: 289 TEDGQI-EESY-SISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGII 346
             + ++    Y +I+ G+    +             D   +TD E +E  + L   EGI 
Sbjct: 271 QAETKVRRHRYDTIAEGV---GIDRLTENFMLAKVDDAFKVTDQEIVEMSRFLLREEGIF 327

Query: 347 PALESSHALAHALKMMRE-NPDKEQLLVVNLSGRGDK 382
               S    A A++  R+  P    + V+  SG+   
Sbjct: 328 VGSSSGLNCAAAVRAARKLGPGHTIVTVLCDSGQRHL 364


>UniRef50_Q2RWP4 L-threonine ammonia-lyase n=1 Tax=Rhodospirillum rubrum ATCC 11170
           RepID=Q2RWP4_RHORT
          Length = 330

 Score = 80.0 bits (196), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 57/210 (27%), Positives = 77/210 (36%), Gaps = 30/210 (14%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTN---QVLGQALLAKRMGKTEIIAETGAG 113
           T L +   + A     L +K E L   G+ K       L Q   A R     +I  + +G
Sbjct: 30  TPLVESPVLNASIGGRLLVKAECLQRTGSFKMRGATNALAQMDDAAR--ARGVITHS-SG 86

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVI--PVHSGSATLKDACN 171
            HG A A A+   GL+  + M       +   +   R  GAEV+  P H+   T+     
Sbjct: 87  NHGQALASAARAFGLRATVVMPDDAPALK---IELTRAHGAEVVFCPRHAREQTVARLAG 143

Query: 172 EALRDWSGSYETAHYMLGTAAGPHPYPT-IVREFQRMIGEETKAQILEREGRLPDAVIAC 230
           E                  A   HPY T  V   Q  +G E   Q     G +PD V+ C
Sbjct: 144 E----------------SGAVVIHPYETPAVIAGQGTVGLEIVEQC-AAIGVVPDQVLVC 186

Query: 231 VGGGSNAIGMFADFIN-ETNVGLIGVEPGG 259
            GGG    G+          V +I VEP G
Sbjct: 187 CGGGGLTAGVALAIDRLLPGVPVIAVEPEG 216


>UniRef50_A4RXR0 Predicted protein n=16 Tax=cellular organisms RepID=A4RXR0_OSTLU
          Length = 387

 Score = 79.6 bits (195), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 65/329 (19%), Positives = 108/329 (32%), Gaps = 44/329 (13%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE---IIAETGAG 113
           T + K   +       +Y+K E      + K    +     A+R G  +    + E  +G
Sbjct: 45  TPVIKVNRLAPA-GIDMYVKCEYFNPLSSVKDRLAVAVITDAERRGLLKPGDTVVEATSG 103

Query: 114 QHGVASALASALLGLKCRIYMGAK-DVERQSPNVFRMRLMGAEVIPVHSGSATLKD-ACN 171
             G+A A+A A  G +C I M     VER       MR++GA+VI    G       A  
Sbjct: 104 NTGIAVAMACAQRGYRCVICMAEPFSVER----RKIMRMLGAKVIVTPKGGKGTGMVAKA 159

Query: 172 EALRDWSGSYETAHYM---LGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVI 228
           E L +     +   ++       A P              G E    + +  G+  D  +
Sbjct: 160 EELAE-----KNGWFLCRQFENEANP-------AYHASTTGPEI---LRDFAGKKLDYFV 204

Query: 229 ACVGGGSNAIGMF---ADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAP 285
              G G    G+     +   +T V L+  E         +          G +    A 
Sbjct: 205 TGYGTGGTFQGVARTLKESRPDTKVILLEPEAAALVTSGIKTERKPTGAPNGSHPAFAAH 264

Query: 286 MMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGI 345
            +Q           +  GL+          L      + V I   +A++  + L   EGI
Sbjct: 265 PVQGWTPDFIPL-VLENGLNM--------NLYD----ELVKIEGGDAVKTAQALARSEGI 311

Query: 346 IPALESSHALAHALKMMRENPDKEQLLVV 374
              +      A ALK+  + P    +L +
Sbjct: 312 FTGISGGATFAGALKVAEKAPKGSVILAM 340


>UniRef50_B6JWQ1 Threonine dehydratase n=1 Tax=Schizosaccharomyces japonicus yFS275
           RepID=B6JWQ1_SCHJY
          Length = 605

 Score = 79.6 bits (195), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 57/205 (27%), Positives = 84/205 (40%), Gaps = 22/205 (10%)

Query: 55  RPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQ-ALLAKRMGKTEIIAETGAG 113
           + T LTK   I+ G    +YLKREDL    + K      + A L     K  +IA   AG
Sbjct: 117 KETPLTKGVVISEGVGCPVYLKREDLTPVFSFKLRGAYNKMASLTPEETKNGVIA-CSAG 175

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
            H    A A+  +G+K  I M     E +  NV   + +GAE + V        D  +EA
Sbjct: 176 NHAQGVAYAARHMGIKATIIMPRNTPEVKWKNV---QRLGAEAVLV-------GDNFDEA 225

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
             +        H +      P+  P  V   Q  I +E   Q+     +  DA+   VGG
Sbjct: 226 KAE-CTRLAKEHNLP--IIHPYDDP-YVIAGQGTIAKEVLQQVDL---KKLDAIYIAVGG 278

Query: 234 GSNAIGMFADFINE--TNVGLIGVE 256
                G+ + ++     +V +IGVE
Sbjct: 279 AGLLAGV-SAYVKRLAPHVKVIGVE 302


>UniRef50_Q64CL8 Threonine synthase n=1 Tax=uncultured archaeon GZfos1D1
           RepID=Q64CL8_9ARCH
          Length = 358

 Score = 79.6 bits (195), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 69/333 (20%), Positives = 124/333 (37%), Gaps = 33/333 (9%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE-IIAETGAGQH 115
           T L     +         +K E     G+ K      +   A   G+   +IA TG    
Sbjct: 58  TPLVDLTRLMPQAK-KFLVKYEAANPTGSFKDRGSSLEITKAVTWGRKRAVIASTG--NM 114

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
           G + A  +A   ++C+I +       +   + +M+  GAEV      S    DA N A  
Sbjct: 115 GSSVAAFAAFAKIRCKIIIPDFVNTAK---IVQMKAYGAEVELT---SGDYADAMNIAEN 168

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
                 E+        AG +P+     E  + +G E   Q+     R+PDAVIA +G G+
Sbjct: 169 QVRSDPESF------LAGDYPW---RCEGTKTVGFEIADQM---YWRVPDAVIAPIGNGT 216

Query: 236 NAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIE 295
               ++  F      G+    P   G++  +    ++          +   +   +    
Sbjct: 217 LIWSVWKAFKELMITGITDALPLMVGVQAEKCDPVVRAWEE------RTDTIVPIENPRT 270

Query: 296 ESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHAL 355
            + +I+ G     +    A   S G    + +TD+E L A   L  + G+    E S A+
Sbjct: 271 VASAIACGAPIDGLLALKAIRESGGIC--IRVTDEEILRARDELGSN-GVFV--EPSGAV 325

Query: 356 AHALKMMRENPDKEQLLVVNLSGRGDKDIFTVH 388
           + A      +   ++ +V   +G G KD++ + 
Sbjct: 326 SFAGARKTGDLLDQKTVVCIATGHGLKDMYGIE 358


>UniRef50_P55708 Putative cysteine synthase n=14 Tax=Proteobacteria RepID=Y4XP_RHISN
          Length = 336

 Score = 79.2 bits (194), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 76/331 (22%), Positives = 122/331 (36%), Gaps = 54/331 (16%)

Query: 68  GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK---TEIIAETGAGQHGVASALASA 124
           G N TL LK E    GG+ K        + A + G+      I E+ +G  G   ALA+ 
Sbjct: 22  GRNATLVLKIEKNNPGGSMKDRMARSMVIAALQDGRLPPGGTIVESSSGNTGTGLALAAL 81

Query: 125 LLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWS---GSY 181
             GL+   ++   D       +  MR +GAE+  V       + A  E  R  +      
Sbjct: 82  EFGLR---FIAVVDHHAAPDKIRMMRALGAEIRYVEGDFREDEVAVVERQRLAAQLGAQL 138

Query: 182 ETAHYMLGT--AAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIG 239
             A +M  +   A P  Y  +V        +E  AQ+ +      DA + CVG G +  G
Sbjct: 139 PGALFMNQSDNPANPEGYTGLV--------DELVAQLPDGI----DAFVGCVGTGGSMTG 186

Query: 240 MFADF-INETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESY 298
           +      N   V  I VEP G  +         + G  G   G        E G++    
Sbjct: 187 ISQRLKRNNPAVRTIAVEPAGSIVFGKPGHPYYQSGT-GTPAG-------DEVGKV---- 234

Query: 299 SISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHA 358
                LD+  +          G    V +TD +A E  + +   +G++    +  A+  A
Sbjct: 235 -----LDYGCI--------DEG----VQVTDTQAFETARYIARRKGLLVGGSTGGAIYKA 277

Query: 359 LKMMRENPDKEQLLVVNLSGRGDKDIFTVHD 389
           L+ +        ++     G G+K + T+ D
Sbjct: 278 LEFIGAGKLTGTVVTTVADG-GEKYLGTIFD 307


>UniRef50_B9LPA5 Pyridoxal-5'-phosphate-dependent protein beta subunit n=3
           Tax=Halobacteriaceae RepID=B9LPA5_HALLT
          Length = 415

 Score = 79.2 bits (194), Expect = 3e-13,   Method: Composition-based stats.
 Identities = 68/363 (18%), Positives = 115/363 (31%), Gaps = 66/363 (18%)

Query: 57  TALTKCQNITAGTNT-TLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           T L +C  +        + LK E     G  K     GQ+L           A T A QH
Sbjct: 81  TPLVECPALADAMGVGRVLLKDEGANPTGTFKDR---GQSL-----------AMTAARQH 126

Query: 116 GVA-------------SALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGA--EVIPVH 160
           G A             +A  +A   L   +Y+ ++    Q        + GA   V    
Sbjct: 127 GAADIALNSAGNAGQAAAAYAARADLDAHVYLPSRAGFTQKAMT---EVHGADLTVTDPI 183

Query: 161 SGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILERE 220
            G++ + DA   A  D   ++    Y   T   P+       E ++ +  E   Q+    
Sbjct: 184 DGNSQIGDA-GRAYADAMDAHPD-WYSAKTFVTPYR-----HEGKKTMALELLEQLD--- 233

Query: 221 GRLPDAVIACVGGGSNAIGMFADFIN-------ETNVGLIGVEPGGHGIETGEHGAPLKH 273
              PD V+   GGG   +GM             +  V +   +  G           +  
Sbjct: 234 WEAPDGVVYPTGGGVGLVGMHKAAHEVRELGWTDELVPMYAAQAAGC-------APVVDA 286

Query: 274 GRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEAL 333
              G       P    ++     +         P   P             V+ TD E L
Sbjct: 287 YEAGADRHEPVP---DDEVDTACNGIAIPD---PGASPLILDAIRESEGGAVATTDREIL 340

Query: 334 EAFKTLCLHEGIIPALESSHALAHALKMMR--ENPDKEQLLVVNLSGRGDKDIFTVHDIL 391
           +A   +   EG+      +  ++ A  +    E    + ++++N +G G+KD+  +   L
Sbjct: 341 DAAIEVARAEGLEVGATCAACVSGAFALAESGEFGPDDTVVLLN-TGAGNKDVDALRAHL 399

Query: 392 KAR 394
             R
Sbjct: 400 GER 402


>UniRef50_D1C5Q2 Cystathionine beta-synthase n=30 Tax=Bacteria RepID=D1C5Q2_SPHTD
          Length = 479

 Score = 78.8 bits (193), Expect = 3e-13,   Method: Composition-based stats.
 Identities = 72/348 (20%), Positives = 121/348 (34%), Gaps = 54/348 (15%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE---IIAETGAG 113
           T L +   +T G  T +  K E +  GG+ K          A+R G  +    I E  +G
Sbjct: 26  TPLVRLNRVTQGITTPVVAKVEFVNPGGSVKDRIGFRMIEEAERRGWLKPGGTIVEPTSG 85

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
             GV  A+A+A+ G +C   M  K  + +   V  +R  GAEV+   +            
Sbjct: 86  NTGVGLAMAAAVRGYRCVFVMPDKVSQEK---VALLRAYGAEVVTTPTAVPR-----ESP 137

Query: 174 LRDWSGSYETAHYMLGTAA-GPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVG 232
              +S +      + G      +  P   R      G E   Q            +A VG
Sbjct: 138 ESYYSVADRLTREIPGAFQPNQYFNPINPRAHYETTGPEIWRQ----TEGKVTHFVAGVG 193

Query: 233 GGSNAIGMFADFINE--TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTE 290
            G    G+   ++ E   N+ +IG +P G      ++  P K   +G  F          
Sbjct: 194 TGGTISGV-GRYLKEQNPNIKVIGADPEGSIYTDPDNIRPYKVEGIGEDF---------- 242

Query: 291 DGQIEESYSISAGLDFPSVGPQHAYLNSTGRA-DYVSITDDEALEAFKTLCLHEGIIPAL 349
                          +P                +++ ++D ++    + +   EG++   
Sbjct: 243 ---------------WPGT-------FDRAVVDEFIQVSDRDSFLTARRVTREEGLLVGG 280

Query: 350 ESSHALAHALKMMRENPDKEQLLVVNL--SGRGDKDIFTVHDILKARG 395
               A+  AL++     D E L+VV L  SGRG        D ++  G
Sbjct: 281 SGGTAVWAALQVAARLDDPESLVVVLLPDSGRGYLSKVYNDDWMRENG 328


>UniRef50_B9KBA9 Tryptophan synthase beta chain 2 n=1 Tax=Thermotoga neapolitana DSM
           4359 RepID=B9KBA9_THENN
          Length = 154

 Score = 78.4 bits (192), Expect = 4e-13,   Method: Composition-based stats.
 Identities = 23/95 (24%), Positives = 35/95 (36%), Gaps = 9/95 (9%)

Query: 18  PQILMP-ALRQLEEAF-----VSAQKDPEFQAQFNDLLKNYA-GRPTALTKCQNITAGTN 70
           P+   P +  +L   F          +  F      +L+ YA  RPT L +   +     
Sbjct: 53  PETKKPVSPEKLSVIFPMSLIEQEVSEERFIEIPEPVLREYAVYRPTPLIRATFLEEYLQ 112

Query: 71  --TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK 103
               +Y K E +   G+HK N  + QA   K   K
Sbjct: 113 TPARIYYKYEGVSPTGSHKPNTAIAQAYYRKLARK 147


>UniRef50_B3TC24 Putative Pyridoxal-phosphate dependent enzyme n=1 Tax=uncultured
           marine microorganism HF4000_APKG10F17 RepID=B3TC24_9ZZZZ
          Length = 344

 Score = 78.4 bits (192), Expect = 4e-13,   Method: Composition-based stats.
 Identities = 71/345 (20%), Positives = 124/345 (35%), Gaps = 40/345 (11%)

Query: 56  PTALTKCQNITAGTNTTLYLKREDL--LHGGAHKTNQVLGQALLAKRMGKTEIIAETGAG 113
           PT L    N++   N  +Y+KR+DL  L  G  K  ++  +   AK  G   ++   G+ 
Sbjct: 21  PTPLQYLPNLSDSLNLKIYIKRDDLTDLALGGDKARKLEYEIAEAKAHGCDTLVT-CGSA 79

Query: 114 QHGVA--SALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSA-TLKDAC 170
           Q  +A  +  A+   G++  + +   D  +   N+  + LMGA +  V +G    L++  
Sbjct: 80  QSNLARLTTAAARKCGMEVSVVLSKDDYTQLQGNLLTVVLMGATIKIVETGDHWDLEEHA 139

Query: 171 NEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIAC 230
                D +      HY+  +   P      VR      G E   Q+ E +    D +   
Sbjct: 140 LALCDDLTEQGRRPHYIPVSGTTPLSCLGYVRG-----GLEIVNQMKEAQLNF-DHIYTP 193

Query: 231 VGGGSNAIGMFADFINET-NVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQT 289
            G G     +   F +        G+       +  E+   L      +  G   P+ Q 
Sbjct: 194 FGTGGIFTALLYTFRHSHLESAFHGISVNRLRSQCVENLETLWEALTRLLDGDM-PVPQ- 251

Query: 290 EDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPAL 349
           +  Q+ + +                     G+ +Y   TD   LEA   +   EGI+   
Sbjct: 252 KGHQVYDQF--------------------IGK-EYGDPTDS-CLEAISIMAKREGILLDP 289

Query: 350 -ESSHALAHALKMMRENP-DKEQLLVVNLSGRGDKDIFTVHDILK 392
             S    +  L   R +  +    +++  SG G   +F   D LK
Sbjct: 290 VYSGKMFSGFLDHHRNDCFNSGDHILLLHSG-GVPALFAYQDALK 333


>UniRef50_A3ERN7 Cysteine synthase n=2 Tax=Leptospirillum sp. Group II
           RepID=A3ERN7_9BACT
          Length = 312

 Score = 78.4 bits (192), Expect = 4e-13,   Method: Composition-based stats.
 Identities = 74/333 (22%), Positives = 113/333 (33%), Gaps = 56/333 (16%)

Query: 49  LKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQV---LGQALLAKRMGKTE 105
           L    GR T L   +++T G +  +++K E    GG+ K       + QA     +    
Sbjct: 12  LDQLIGR-TPLVALESMTRGLDRVVWVKLESRNLGGSVKDRPARYMVEQAERNGELAPGG 70

Query: 106 IIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSAT 165
            I E  +G  G+A A    L G    I M     +     V+ ++ +GAEV    +    
Sbjct: 71  RIVEATSGNTGIALAQIGVLKGYPVVIVMPEGVSQE---RVYHLKALGAEVELTPA-RDG 126

Query: 166 LKDACNEALRDWSGSYETAHYMLGTAAGPHPY--PTIVREFQRMIGEETKAQILEREGRL 223
           +  A   A    S          G+   P  +  P       R  G E   Q+    GRL
Sbjct: 127 MAGAIRRAETLLSERP-------GSFM-PRQFENPANPESHYRTTGPEILDQL----GRL 174

Query: 224 PDAVIACVGGGSNAIGMFADFINE--TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFG 281
           PD  +A   G    I     F+ E    V + G+EP    + +G    P  H   GI  G
Sbjct: 175 PDGFVA-GIGTGGTITGVGRFLRERHEAVRIWGLEPASSAVLSGSSPGP--HRIQGIGAG 231

Query: 282 MKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCL 341
               ++        E                              I D  A+E  + L  
Sbjct: 232 FVPKILDRSVCDKIEP-----------------------------IDDRTAIETMRRLTR 262

Query: 342 HEGIIPALESSHALAHALKMMRENPDKEQLLVV 374
            EGI+  + S   +A AL + R  P    ++ +
Sbjct: 263 EEGIMAGISSGANVAGALLLARTLPPGSHVVTI 295


>UniRef50_C2BGX3 Threonine ammonia-lyase n=3 Tax=Anaerococcus RepID=C2BGX3_9FIRM
          Length = 394

 Score = 78.4 bits (192), Expect = 5e-13,   Method: Composition-based stats.
 Identities = 78/348 (22%), Positives = 127/348 (36%), Gaps = 62/348 (17%)

Query: 56  PTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQAL-LAKRMGKTEIIAETGAGQ 114
           PT L   +  +  +N  +Y+K E+L   G+ K      +   L K      II  + AG 
Sbjct: 17  PTHLIYSEVFSDSSNNNVYIKPENLQKTGSFKLRGAYNKLSKLDKESADKGIITAS-AGN 75

Query: 115 HGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEAL 174
           H    A ++  LG+K  I M       +     +    GAEV+        L  A  +  
Sbjct: 76  HAQGVAFSAQKLGMKAVICMPEHTPMIKVDGTLK---YGAEVV--------LHGASFDEC 124

Query: 175 RDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGG 234
           +D +          G    P      V E Q  IG E   ++     +  D V+  VGGG
Sbjct: 125 KDHALKLAEEK---GYTFIPPFDDLDVIEGQGTIGLEIVEEL-----KYVDYVLVPVGGG 176

Query: 235 SNAIGMFADFIN-ETNVGLIGVEP-GGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDG 292
               G+          + +IGVEP     ++       +K G +    G+          
Sbjct: 177 GLISGVAKCLKQISPLIKVIGVEPYSARSMKEA-----VKLGHIVTLEGVDT-------- 223

Query: 293 QIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAF-------KTLCLHEGI 345
                  I+ G    +VG  +  +      D++++TD+E L AF       K +    GI
Sbjct: 224 -------IADGTAVATVGKLNYEICKDNVDDWITVTDEEILMAFIKLIEKHKLIAEPSGI 276

Query: 346 IPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
           +P       LA   K+     +K  + VV  SG G+ D+  +  ++  
Sbjct: 277 LP-------LAALDKL--NFFNKNVVCVV--SG-GNIDMSFISQLIDR 312


>UniRef50_A9ED40 Pyridoxal-phosphate dependent enzyme (Fragment) n=1
           Tax=Oceanibulbus indolifex HEL-45 RepID=A9ED40_9RHOB
          Length = 227

 Score = 78.0 bits (191), Expect = 6e-13,   Method: Composition-based stats.
 Identities = 44/181 (24%), Positives = 63/181 (34%), Gaps = 16/181 (8%)

Query: 55  RPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQV-LGQALLAKRMGKTEIIAETGAG 113
           R T L     +       +++K E L H G+ K        + L        +IA + +G
Sbjct: 18  RRTPLLNSHFLDEIAGRRVWVKPECLQHTGSFKFRGAWSALSALNPEARAKGVIAYS-SG 76

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
            H    ALAS + G    I M       +  N    R  GAEV+        L D   E+
Sbjct: 77  NHAQGVALASKMHGAPAVIIMPKDSPRLKIANT---RAYGAEVV--------LYDRAGES 125

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
             +          +  T   P+  P  V   Q   G E   Q  E   +  D ++ C GG
Sbjct: 126 REEIGAKLAEERGL--TLIKPYDEPQ-VIAGQGTTGLEIAQQAAEAGIKSADVIVCCGGG 182

Query: 234 G 234
           G
Sbjct: 183 G 183


>UniRef50_A6GXZ8 Cysteine synthase/cystathionine beta-synthase family protein n=23
           Tax=Bacteroidetes RepID=A6GXZ8_FLAPJ
          Length = 355

 Score = 78.0 bits (191), Expect = 6e-13,   Method: Composition-based stats.
 Identities = 66/329 (20%), Positives = 114/329 (34%), Gaps = 60/329 (18%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE---IIAETGAG 113
           T L K   IT G     Y K E    G + K    L     A++ G  +    I ET +G
Sbjct: 27  TPLIKIDKITEGLKGNFYAKVEAFNPGHSTKDRIALYIIEEAEKQGILKPGDTIIETTSG 86

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
             G + A+ S + G  C I+  A   +  +  +  +R MGA+V    +            
Sbjct: 87  NTGFSLAMVSIIKGYDC-IF--AISSKSSADKIDMLRSMGAKVYVCPA------------ 131

Query: 174 LRDWSGSYETAHYML---------GTA-AGPHPYPTIVREFQRMIGEETKAQILEREGRL 223
               S   E ++Y +         G+     +     +    +  G E   Q   +    
Sbjct: 132 --HVSADDERSYYSVAKRLHEEIKGSVYINQYFNHLNIEAHYKSTGPEIWEQTNGKI--- 186

Query: 224 PDAVIACVGGGSNAIGMFADFINE--TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFG 281
              +IAC G G    G+   F+ E   N+ ++GV+  G  I+  ++    +  +  IY  
Sbjct: 187 -THLIACTGTGGTISGIAK-FLKEKNPNIRILGVDAYGSVIK--KYHETKEFDKDEIY-- 240

Query: 282 MKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCL 341
                ++     +  S      LDF         L       +V +TD+E+    + +  
Sbjct: 241 --PYRIEGLGKNLIPSA-----LDF--------DLID----KFVKVTDEESAHMTRNIAK 281

Query: 342 HEGIIPALESSHALAHALKMMRENPDKEQ 370
            EG+     S   +    +   E    E+
Sbjct: 282 VEGLFVGYTSGAVVQAIKQYAEEGEFDEK 310


>UniRef50_P29848 Cysteine synthase B n=436 Tax=cellular organisms RepID=CYSM_SALTY
          Length = 303

 Score = 78.0 bits (191), Expect = 6e-13,   Method: Composition-based stats.
 Identities = 65/340 (19%), Positives = 121/340 (35%), Gaps = 71/340 (20%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE---IIAETGAG 113
           T L K Q +     + +++K E     G+ K    L   + A++ G+ +   ++ E  +G
Sbjct: 11  TPLVKLQRLGPDNGSEIWVKLEGNNPAGSVKDRAALSMIVEAEKRGEIKPGDVLIEATSG 70

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS-----GSATLKD 168
             G+A A+ +AL G + ++ M   ++ ++      MR  GAE+I V       G+  L  
Sbjct: 71  NTGIALAMIAALKGYRMKLLMP-DNMSQE--RRAAMRAYGAELILVTKEQGMEGARDLAL 127

Query: 169 ACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVI 228
           A +E                G        P          G E   Q   R        +
Sbjct: 128 AMSERGE-------------GKLLDQFNNPDNPYAHYTTTGPEIWRQTSGRI----THFV 170

Query: 229 ACVGGGSNAIGMFADFIN--ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPM 286
           + +G      G+ + F+   E  V ++G++P     E G     ++        G+    
Sbjct: 171 SSMGTTGTITGV-SRFLREQEKPVTIVGLQP-----EEGSSIPGIRRWPAEYMPGIFNAS 224

Query: 287 MQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGII 346
           +                                   + + I  ++A    + L + EGI 
Sbjct: 225 LVD---------------------------------EVLDIHQNDAENTMRELAVREGIF 251

Query: 347 PALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFT 386
             + S  A+A AL++ R  P    ++V  +  RGD+ + T
Sbjct: 252 CGVSSGGAVAGALRVARATPG--AIVVAIICDRGDRYLST 289


>UniRef50_A6F8H1 Threonine dehydratase n=1 Tax=Moritella sp. PE36 RepID=A6F8H1_9GAMM
          Length = 505

 Score = 77.3 bits (189), Expect = 9e-13,   Method: Composition-based stats.
 Identities = 47/196 (23%), Positives = 74/196 (37%), Gaps = 26/196 (13%)

Query: 25  LRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGG 84
           ++ +E  F      P F     D LK     PT + +  N++  TN  +YLKREDL    
Sbjct: 3   IQIIESYFNKIVTSPVF-----DYLK-----PTPVDRLVNLSKQTNNDIYLKREDLQDIN 52

Query: 85  AHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSP 144
           + K      + +    +     +    AG H    A     LG    I M     + +  
Sbjct: 53  SFKIRGAYQKIISLPLIQLNRGVVAASAGNHAQGVAKVCKELGTTATIVMPDTTPKIK-- 110

Query: 145 NVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTI-VRE 203
            V  +R  GA V  V  G        +EA R ++ +   +  +  +    HP+  I V  
Sbjct: 111 -VDAVRSYGANV--VLHGVNY-----DEAYR-YAYNLADSRDL--SLI--HPFDDIEVIC 157

Query: 204 FQRMIGEETKAQILER 219
            Q  IG E  +Q+ + 
Sbjct: 158 GQGTIGLEFASQVEQL 173


>UniRef50_A2BKW1 Threonine synthase n=1 Tax=Hyperthermus butylicus DSM 5456
           RepID=A2BKW1_HYPBU
          Length = 366

 Score = 77.3 bits (189), Expect = 9e-13,   Method: Composition-based stats.
 Identities = 71/332 (21%), Positives = 118/332 (35%), Gaps = 37/332 (11%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T L + + +       ++ K E L   G+ K          A RMG   ++ +T +G  G
Sbjct: 70  TPLVE-RRVE---GVRVFFKLEYLNPTGSFKDRGTSLALAYASRMGFRLVVEDT-SGNTG 124

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD 176
           ++ A  +A  GL+ RIYM     E +      +R +G EV+   S       A       
Sbjct: 125 ISVAAYAAAYGLRARIYMPVNAPEGK---KRLVRALGGEVVLTPS-RGEAAQAV-----L 175

Query: 177 WSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSN 236
           W        Y+       H +     E  + I  E        +G    AV+  VG G  
Sbjct: 176 WELKKPDVFYV------AHTWSPFYVEGAKTIAFEAFE-----DGFRGSAVLVPVGSGGL 224

Query: 237 AIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEE 296
            +G++  F      GLI   P    +  G    PL     G     K P  +    ++ +
Sbjct: 225 LLGIYHGFRELVEQGLIDSVPRIIAV-QGYSNPPLYRAVYG-----KEPEAEERSSRLAD 278

Query: 297 SYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALA 356
              +S   + P +G     + +TG    + + D+      K L    G I    S+    
Sbjct: 279 GLMVS---EPPRLGEAAEAVKATGGC-VILVDDEGIRRGLKMLASM-GFIVEPTSATLYP 333

Query: 357 HALKMMRENP-DKEQLLVVNLSGRGDKDIFTV 387
             L+ +     DK + ++  L+G G K +   
Sbjct: 334 ALLEAVERGCIDKGEEVLAPLTGSGLKTLEYF 365


>UniRef50_A1WTA6 L-threonine synthase n=12 Tax=Bacteria RepID=A1WTA6_HALHL
          Length = 379

 Score = 77.3 bits (189), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 72/343 (20%), Positives = 123/343 (35%), Gaps = 43/343 (12%)

Query: 57  TALTKCQNITAGTN--TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQ 114
           T L +   I A       LY+K E L   G+ K   +      A   G   II  +  G 
Sbjct: 34  TPLIQLTRIPAELGRDVDLYVKFEGLNPTGSFKDRGMTMAVTKAVEQGAKAIICAS-TGN 92

Query: 115 HGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEAL 174
              ++A  +A  G+ C + +    +         M   GA+V+ +           +  +
Sbjct: 93  TSASAAAYAARAGISCFVLIPDGKIAMGKLAQAIM--HGAQVLQIRGN-------FDAGM 143

Query: 175 RDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGG 234
           R      E A   +  +  P+       + Q+    E    I+E   R PD     VG  
Sbjct: 144 RLVKELAEHAPLTIVNSINPYR-----LQGQKTAAFE----IIEELERAPDYHCLPVGNA 194

Query: 235 SNAIGMFADFINETNVGLIGVEPGGHGIE----TGEHGAPLKHGRV---GIYFGMKAPMM 287
            N    +  +      G  G E              + + L   R    G      AP +
Sbjct: 195 GNITAHWIGY--SECAGRTGDEQLTAACAFCGGQCRYASALVERRPRMVGYQASGSAPFL 252

Query: 288 QTEDGQIEESYSISAGLDFPSVG-PQ-----HAYLNSTGRADYVSITDDEALEAFKTLCL 341
           +   G + E  +++  +    +G PQ      A    +G   +  ++D+E L+A + L  
Sbjct: 253 R--GGPVAEPETVATAIR---IGDPQSWDYAQAVREESG-GWFDELSDEEILQAQRMLAD 306

Query: 342 HEGIIPALESSHALAHALKMMRENPDKE-QLLVVNLSGRGDKD 383
           HEG+     S+ ++A A++ +R     E   +V  L+G G KD
Sbjct: 307 HEGVFCEPASATSVAGAMRDIRSGRIPEGSTVVCTLTGHGLKD 349


>UniRef50_Q3M5I1 Cystathionine beta-synthase n=5 Tax=cellular organisms
           RepID=Q3M5I1_ANAVT
          Length = 461

 Score = 76.9 bits (188), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 68/330 (20%), Positives = 122/330 (36%), Gaps = 52/330 (15%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE---IIAETGAG 113
           T L +   +TA   + +Y K E L  GG+ K    L     A++ G+ +    I E  AG
Sbjct: 14  TPLVRLNRVTANVQSPIYAKVEYLNPGGSTKDRIALSMIENAEKTGQIQPGGTIIEATAG 73

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
             GV  AL +A+   +C   M  K  + +   +  ++  GAEV+   +         +  
Sbjct: 74  NTGVGLALIAAVKKYRCIFVMPDKMSQDK---INLLKAYGAEVVVTPTSVP-----PDSP 125

Query: 174 LRDWSGSYETAHYMLGTAAGPHPY--PTIVREFQRMIGEETKAQILEREGRLPDAVIACV 231
                 +   A  + G A  P+ +  P          G E  A    +     D  +A +
Sbjct: 126 ESYNGVAERLAKEIPG-AYRPNQFENPNNPLAHYLTTGPEIWADSQGKI----DVFVAGM 180

Query: 232 GGGSNAIGMFADFINETNVGLIGVEPGGHG-IETGEHGAPLKHGRVGIYFGMKAPMMQTE 290
           G G    G+   ++ E N  +I V     G I +G+     K   +G  F     + +T 
Sbjct: 181 GTGGTISGVAK-YLKEQNPNIIIVGADPEGSILSGDSPKSYKVEGIGEDF-----IPKTF 234

Query: 291 DGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALE 350
           + Q+ +                          + + ++D E+    + L   EG++    
Sbjct: 235 NRQLVD--------------------------EMIRVSDKESFNMARRLAREEGLLVGGS 268

Query: 351 SSHALAHALKM-MRENPDKEQLLVVNLSGR 379
               +A ALK   R +  K  ++++  +GR
Sbjct: 269 CGTVVAAALKYAARLSQPKYIVVLLPDTGR 298


>UniRef50_A3ZYZ6 Threonine synthase n=2 Tax=Planctomycetaceae RepID=A3ZYZ6_9PLAN
          Length = 353

 Score = 76.9 bits (188), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 73/344 (21%), Positives = 116/344 (33%), Gaps = 29/344 (8%)

Query: 57  TALTKCQNITAGTNTT-LYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           T L + Q I        LY K E +   G++K           +R GK  +IA T +G  
Sbjct: 11  TPLVRSQRIGPALGLKNLYFKLETVNPTGSYKDRFAAAAIADMQRQGKRRVIA-TSSGNT 69

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVH--SGSATLKDACNEA 173
           G A A  +A  G+ C I +       +     +M   GA++  +      A +  A  E 
Sbjct: 70  GSALAAYAAAAGMACTIAIVDGAPAGKL---RQMMAYGADIKKIQGFGHDAKVTQATFEF 126

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
           L+      +    +  +A    P      E    IG E  AQ+    G+  D V +C GG
Sbjct: 127 LQQLGAQPDAQLQI--SAYHYSPVGMGGVE---AIGREIAAQLSAH-GQQADHVFSCAGG 180

Query: 234 GSNAIGMFADFINETNVGLIGVEP---GGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTE 290
           G   + +   F        I   P       I       PL+ G       +    +   
Sbjct: 181 GGLTLAVARGFCTAVEFESIDASPHVHCVQPIGNNTIAGPLRDGSDQAQATVCTTKISGL 240

Query: 291 DGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALE 350
                    +++ +D        A   S G      + D E  E+   L   EGI     
Sbjct: 241 Q--------VASVID--GDAVIAACRASGG--TGWLVEDAEIYESQTELARQEGIFSEPA 288

Query: 351 SSHALAHALKMMRENPDKEQLLVVNL-SGRGDKDIFTVHDILKA 393
            +  L    + +          ++ L +G G KD+ +V  +L A
Sbjct: 289 GAVPLTGLKQALAAGQIPSTATIICLVTGTGFKDLDSVDAMLGA 332


>UniRef50_Q3A093 L-threonine ammonia-lyase n=9 Tax=Desulfuromonadales
           RepID=Q3A093_PELCD
          Length = 415

 Score = 76.9 bits (188), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 74/351 (21%), Positives = 119/351 (33%), Gaps = 64/351 (18%)

Query: 55  RPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAE---TG 111
           R T L      +      LY K E+L   G+ K            R     + A      
Sbjct: 19  RRTELIHSHFFSEQIGLPLYFKCENLQRSGSFKVRGAF---HFMARQPAQRLAAGVVTAS 75

Query: 112 AGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACN 171
           AG H    AL++A LG+   + M       +       R  GAEV+          DA  
Sbjct: 76  AGNHAQGVALSAARLGVAATVVMPENTPLAKMQAT---RGYGAEVVL---HGTVFDDAQE 129

Query: 172 EALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACV 231
           EALR      +  H +L      HP   ++   Q  IG E    +        D ++A V
Sbjct: 130 EALR-----LQHTHDLLYVPPFDHP---LIMAGQGTIGLEIIEDLP-----DVDTLLAPV 176

Query: 232 GGGSNAIGMFADFIN-----ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPM 286
           GGG    G+ ++           V +IGVE              L   R G   G     
Sbjct: 177 GGG----GLISEVATAIKALRPTVRVIGVEAAAAPAA-------LLSRRQGHIVG----- 220

Query: 287 MQTEDGQIEESYSISAGLDFPSVG----PQHAYLNSTGRADYVSITDDEALEAFKTLCLH 342
                  +  ++S++ G+    +G    P    L      + V++ +++  +A   L   
Sbjct: 221 -------LSGAHSLADGIALKRIGEQTFPVIEALVD----ELVTVNEEQIAQAIVALMEK 269

Query: 343 EGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
             ++     +  LA  L   R       + +  LSG G+ D+ T+  ++  
Sbjct: 270 TRLVVEGAGAVGLAALLHAARPLARGRTVCL--LSG-GNIDVQTIAQVVDR 317


>UniRef50_B2JXT2 Pyridoxal-5'-phosphate-dependent protein beta subunit n=1
           Tax=Burkholderia phymatum STM815 RepID=B2JXT2_BURP8
          Length = 395

 Score = 76.9 bits (188), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 71/331 (21%), Positives = 119/331 (35%), Gaps = 35/331 (10%)

Query: 57  TALTKCQNITAGTNTT-LYLKREDLLHGGAHK--TNQVLGQALLAKRMGKTEIIAETGAG 113
           T L+    + A      LY K E     G+HK   + ++ Q  L  R    + IA   +G
Sbjct: 75  TPLSSLPRLAATLGIEALYAKNEFANPTGSHKDRMSAIVAQRALDIRA---KTIAVASSG 131

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
             GV+ A  +A  G+ C +         Q+     + + GA +I + S           A
Sbjct: 132 NAGVSMAAYAARAGIDCVV--VTTPDMSQNWRRA-IEMHGARIIAMESSDDRWVLIARHA 188

Query: 174 LR-DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVG 232
            R DW   Y   +Y++    G +P+     +  R I  E   Q        P  ++    
Sbjct: 189 RRGDW---YPATNYLM-PPVGSNPFG---VDGYRAIALELYLQFPAVP---PTDILVPTA 238

Query: 233 GGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDG 292
            G    G+   + +  N GLI V P  H +E        + G      GM          
Sbjct: 239 RGDLLWGIAKGYQDLRNTGLISVTPRVHAVEPFPRIGRAREG-----HGMVC------SN 287

Query: 293 QIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESS 352
              ++  +S G +  +     A       A  V++ D EA      L   EG+   L S+
Sbjct: 288 FSGDTAMVSIGGNTVTFQSLLAL--ELTDASGVAVNDQEASHDRLLLAK-EGLYVELSSA 344

Query: 353 HALAHALKMMRENPDKEQL-LVVNLSGRGDK 382
            A++   K++ +     +  +V+  +  G K
Sbjct: 345 AAVSGLRKLVAQGKIGARSRVVMIATSHGYK 375


>UniRef50_Q01PK6 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit n=1
           Tax=Candidatus Solibacter usitatus Ellin6076
           RepID=Q01PK6_SOLUE
          Length = 339

 Score = 76.9 bits (188), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 69/335 (20%), Positives = 109/335 (32%), Gaps = 54/335 (16%)

Query: 51  NYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAET 110
               R T +             +Y K E+L  GGA K        L          +   
Sbjct: 41  RPLARKTPVFTSAGFDTEAGARVYFKCENLQRGGAFKIRGAANLVLSLPPESLARGVVAY 100

Query: 111 GAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDAC 170
            +G H  A+A+A+  +G+   I M     + +       R  GA ++  +  + +     
Sbjct: 101 SSGNHAQATAIAARHVGVASTIVMPEDAPKSKMEAT---RAHGARIVTYNRFTDS----- 152

Query: 171 NEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIAC 230
            EA+              G    P     ++   Q     E    +LE  G L DA+IA 
Sbjct: 153 REAIAQSILKET------GATLIPPFDHPMIMAGQGTAALE----LLEETGPL-DALIAP 201

Query: 231 VGGG---SNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMM 287
           VGGG   S    +         V + G EP G      +    +  G             
Sbjct: 202 VGGGGLLSGCATIAKAL--HPTVRVFGAEPAG----ANDTFLSMVAGTRIAVH------- 248

Query: 288 QTEDGQIEESYSISAGLDFPSVG----PQHAYLNSTGRADYVSITDDEALEAFKTLCLHE 343
                      +I+ GL  P  G    P    L        + +++DE   A + L L  
Sbjct: 249 ---------PDTIADGLRSPKPGELTFPVIRELAE----RILLVSEDEIRAAVRFLLLRL 295

Query: 344 GIIPALESSHALAHALKMMRENPDKEQLLVVNLSG 378
            I+   E S A+  A  +  + P+  + + V LSG
Sbjct: 296 KILV--EPSGAVPAAALLFHKLPEGIRSVGVILSG 328


>UniRef50_D1AJT1 Threonine dehydratase n=8 Tax=Bacteria RepID=D1AJT1_SEBTE
          Length = 401

 Score = 76.5 bits (187), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 79/341 (23%), Positives = 126/341 (36%), Gaps = 54/341 (15%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T L      +     T+Y+K E+L   G+ K      +  +     K + +  + AG H 
Sbjct: 21  TKLIYSSTFSKEFGNTVYIKPENLQRTGSFKIRGAYNKIFMLSEEEKKKGLIASSAGNHA 80

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD 176
              A A+  LG+K  I M       +     R    GAEV  V  G     +  +EA   
Sbjct: 81  QGVAFAAQKLGVKATIVMPKHTPLIKVEATAR---FGAEV--VLHG-----EVYDEAYEK 130

Query: 177 WSGSYETAHYMLGTAAGPHPY-PTIVREFQRMIGEETKAQILEREGRLPDAVIACV---G 232
                E   Y+       HP+    V   Q  I  E           LPD  I  V   G
Sbjct: 131 AKELQEEKGYIF-----VHPFDDDAVIAGQGTIALEILK-------ELPDVDIIMVPLGG 178

Query: 233 GGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDG 292
           GG  +    A  +    + +IGVEP G           L  G+V                
Sbjct: 179 GGLISGIAAAAKLKNPEIKIIGVEPEG----AASAIKSLNEGKVT--------------- 219

Query: 293 QIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESS 352
           ++ ESY+I+ G     +G            + ++++D E +E+F  L     +I   E+ 
Sbjct: 220 ELSESYTIADGAAVKRIGDTTFEYIKKYVDEIITVSDYELMESFLILVEKHKLI--AEN- 276

Query: 353 HALAHALKMM--RENPDKEQLLVVNLSGRGDKDIFTVHDIL 391
              A  L +   R+  +K++ +V  LSG G+ D+ T+  ++
Sbjct: 277 ---AGILSLAGLRKIKEKDKKIVSVLSG-GNIDVLTISSMI 313


>UniRef50_C1ZHQ7 Threonine dehydratase n=4 Tax=Bacteria RepID=C1ZHQ7_PLALI
          Length = 320

 Score = 76.5 bits (187), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 69/337 (20%), Positives = 124/337 (36%), Gaps = 53/337 (15%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQV-LGQALLAKRMGKTEIIAETGAGQH 115
           T +     +       LY K E+L   G+ K         LL + +    ++  + +G H
Sbjct: 24  TPVLTSHTLNKLCEAELYFKCENLQRTGSFKVRGAHNATFLLEEELAHNGVVTHS-SGNH 82

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
             A ALA    G+   I M     + +  +    R +G  VI     +A  + A ++ ++
Sbjct: 83  AAALALAGKNRGVPAFIVMPGNAPKAKIEST---RRLGGNVILCEPTAAARQMAADQLVQ 139

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLP--DAVIACVGG 233
           +  G+              HP+  +      + G+      LE    +P  DA++A VGG
Sbjct: 140 ETGGTL------------IHPFDDLRI----VAGQ--GTCALELLDEVPHLDAIVAPVGG 181

Query: 234 G---SNAIGMFADFIN--ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQ 288
           G   S    +        +      G EP G   +     A           G++ PM  
Sbjct: 182 GGLLSGTAIVAHHHSQATDHQCLTFGAEPTGAD-DAARSLAT----------GVRQPM-- 228

Query: 289 TEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPA 348
                     +I+ GL   ++G     +     A   +++D+E L+A + L     I+  
Sbjct: 229 ------NSPQTIADGLR-TALGENTFPIIQQHVAAIGTVSDEEILKATRLLWEVMKIVV- 280

Query: 349 LESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIF 385
            E S A+  A  +    P + + + + LSG G+ D+ 
Sbjct: 281 -EPSGAVPFAAVLQNRLPLRGKKVGLILSG-GNLDLD 315


>UniRef50_C5A936 Cysteine synthase n=1 Tax=Burkholderia glumae BGR1
           RepID=C5A936_BURGB
          Length = 341

 Score = 76.5 bits (187), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 77/343 (22%), Positives = 122/343 (35%), Gaps = 58/343 (16%)

Query: 57  TALTKCQNIT-AGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRM-GKTE--IIAETGA 112
           T L   ++++       +Y K E    G + K    L     A+R  G      I E+ +
Sbjct: 13  TPLLHLKSLSDERRGIRVYGKLESYNPGNSVKDRSALQLLRQAERDHGLKPGWSIVESTS 72

Query: 113 GQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEV----IPVHSGS-ATLK 167
           G  G A A+  A  G +   ++   D +    N   +R  G EV     P  +GS    +
Sbjct: 73  GNMGHALAMLCATRGYR---FICVLDPKTPKTNANLVRAFGGEVEMVQQPDETGSYQKKR 129

Query: 168 DACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAV 227
            A  +AL     +              +  P  +       G E  AQ+ +R     DAV
Sbjct: 130 IAVAKALAASVPNCVN--------LDQYNNPAAIDAHYYSTGPEIVAQLADRL----DAV 177

Query: 228 IACVGGGSNAIGMF-ADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPM 286
           I     GS+  G+       +    ++GVEP G  +  G +   L++G            
Sbjct: 178 IVSASTGSHLSGIARYVKERDPQTRVVGVEPDGSVVFGGSYRPHLQNG------------ 225

Query: 287 MQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGII 346
                          AGL F   G     L      + + I D +A    + L L EG++
Sbjct: 226 ---------------AGLSFQP-GNIRVELVD----ETMRIADRDAFVGCRRLALDEGLL 265

Query: 347 PALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHD 389
               SS A+AHA +           +V+ L   G K + T++D
Sbjct: 266 LG-GSSGAIAHAARRYVAGCQGPANIVLVLPDSGTKYLDTIYD 307


>UniRef50_B2A8I6 Cysteine synthase n=4 Tax=Clostridia RepID=B2A8I6_NATTJ
          Length = 310

 Score = 76.1 bits (186), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 72/333 (21%), Positives = 126/333 (37%), Gaps = 57/333 (17%)

Query: 51  NYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK---TEII 107
           ++ G  T + + QN        + +K E    GG+ KT   LG  + A+R G+     I+
Sbjct: 11  DFVGN-TPMIELQNTNNSHG-NILVKLEAFNPGGSIKTRTALGMIIEAERNGQINENSIL 68

Query: 108 AETGAGQHGVASALASALLGLKCRIYMGAK-DVERQSPNVFRMRLMGAEVIPVHSG---S 163
            E  +G  G+  AL +A+ G + +I M      ER+      +  +GAE+     G   S
Sbjct: 69  VEPTSGNQGIGIALVAAIKGYRAKIVMPESMSTERRKM----IENLGAEIDISPDGNNIS 124

Query: 164 ATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRL 223
            T  +  + A R+ +         +         P   R         T  +I+E+ G  
Sbjct: 125 ETFDNCKSRA-RELAEQDSRVF--ILNQFENKANPNAHR-------LTTAKEIIEQTGEQ 174

Query: 224 PDAVIACVGGGSNAIGMFADFINE--TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFG 281
            DA +A   G    +    + + +    V +I VEP    + +    +   H + GI  G
Sbjct: 175 IDAFVA-GVGTGGTLTGVGEVLKQKYPEVKIIAVEPEKAAVLSQSEISS--HIQQGIGDG 231

Query: 282 MKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCL 341
                                    P V      LN     + +++TD+EALE  K+L  
Sbjct: 232 FI-----------------------PGV------LNQDIIDEVLTVTDEEALETAKSLNR 262

Query: 342 HEGIIPALESSHALAHALKMMRENPDKEQLLVV 374
            +G+   + S   +  A+K+  + P    ++ V
Sbjct: 263 RDGLFSGISSGTNVFAAMKIAEKLPPSANIVTV 295


>UniRef50_C6A468 Cysteine synthase n=1 Tax=Thermococcus sibiricus MM 739
           RepID=C6A468_THESM
          Length = 344

 Score = 76.1 bits (186), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 64/331 (19%), Positives = 115/331 (34%), Gaps = 51/331 (15%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE---IIAETGAG 113
           T + +   I       ++ K E +   G+ K          A++ GK +    IA    G
Sbjct: 20  TPIVRLSKIDKDYPFEIWAKCEFMNPTGSVKDRMAYYMIKEAEKQGKLKPGMTIAIATTG 79

Query: 114 QHGVASALASALLGLKCRIYMGAK-DVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNE 172
             G+A A   +  G    I M  +   ER+  ++    L GA++I    G +   DA   
Sbjct: 80  NTGIAFAAWGSYFGYDVLIVMPEEMSYERKLLDM----LFGAKLIYTPGGES---DAMGA 132

Query: 173 ALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVG 232
              +++   E  +                +      G E   Q+           +A VG
Sbjct: 133 L--EYAKKLEKENPDKYVVLDQWDDEANFKAHYETTGREIIEQL---GAENIKGFVAGVG 187

Query: 233 GGSNAIGMFADFINETNVGLI--GVEPGGHG-----IETGEHGAPLKHGRVGIYFGMKAP 285
            G   +G+    + + N  +I  G+EP          ++GE GA  +H   GI  G   P
Sbjct: 188 SGGTLVGIAKR-LKDANPRIITAGMEPAECPTAEGWFKSGELGAWGRHEVEGIGDGF-VP 245

Query: 286 MMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGI 345
            +  +  Q  +                          D+V+++ DEA+E  + +   E +
Sbjct: 246 SLVEKYKQYID--------------------------DWVTVSSDEAIEMARRIARREAL 279

Query: 346 IPALESSHALAHALKMMRENPDKEQLLVVNL 376
              + S   +  A+K+   +   E   VV +
Sbjct: 280 GVGISSGANVVAAIKLAERHNFGEGDRVVTI 310


>UniRef50_UPI0001978075 cysteine synthase n=1 Tax=Helicobacter cinaedi CCUG 18818
           RepID=UPI0001978075
          Length = 301

 Score = 76.1 bits (186), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 69/327 (21%), Positives = 118/327 (36%), Gaps = 62/327 (18%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK---TEIIAETGAG 113
           T +   +         LY K E L    + K          A + GK     +I E  +G
Sbjct: 14  TPILNLKEFA----PNLYGKCEFLNPSHSVKDRPAYAMIDEAMKQGKINKDTMIVECTSG 69

Query: 114 QHGVASALASALLGLKCRIYMGAK-DVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNE 172
             G++ A+  A  GLK  I M     VER+      +   GA ++   + S  +K A ++
Sbjct: 70  NMGISLAMICASFGLKITITMPESMSVERRKM----ISFFGANLVLTPA-SEGMKGALDK 124

Query: 173 ALRDWSGSYETAHYMLGTAAGPHPYPTI--VREFQRMIGEETKAQILEREGRLPDAVIAC 230
           A ++   S             P  +  +   +  +R    E        EG L D  +A 
Sbjct: 125 A-KEILDSTPNVFM-------PSQFDNLDNKQMHKRTTALEIYESF---EGEL-DYFVAG 172

Query: 231 VGGGSNAIGMFADFINE--TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQ 288
            G G    G+  + + E   ++ +IGVEP    +        L  G+ G      A  +Q
Sbjct: 173 FGTGGTISGV-GEVLKEKIPHIQIIGVEPSASPL--------LSQGQAG------AHKIQ 217

Query: 289 TEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPA 348
                                    + LN       V + ++ A++  + L    G++  
Sbjct: 218 GIGANFIP-----------------SILNRDVIDSIVCVENEVAIQTAQELGRV-GVMVG 259

Query: 349 LESSHALAHALKMMRENPDKEQLLVVN 375
           + S   +A A K+  ENP+K+ L ++N
Sbjct: 260 ISSGANVAMARKIALENPNKKVLTMLN 286


>UniRef50_B0AA90 Cysteine synthase n=4 Tax=Firmicutes RepID=B0AA90_9CLOT
          Length = 303

 Score = 76.1 bits (186), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 67/330 (20%), Positives = 124/330 (37%), Gaps = 60/330 (18%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG---KTEIIAETGAG 113
           T +    N+       +++K E    GG+ K    L     A+  G   K  ++ E  +G
Sbjct: 18  TPIL---NLKEAGYPNVFVKLEKANPGGSIKDRAALYMINGAEEKGILNKDSVLVEATSG 74

Query: 114 QHGVASALASALLGLKCRIYMGAK-DVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNE 172
             G+A A+A  L G K  I M     +ER       ++  GAE++    G+  +  +  +
Sbjct: 75  NTGIALAMAGKLKGYKVIIIMPDTMSIER----RQLVKAFGAELMLTE-GAKGMAGSIEK 129

Query: 173 ALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVG 232
           A      +     Y+     G        R      G E   ++     +    ++A +G
Sbjct: 130 ANELLDKNPN---YI---CLGQFDNEDNPRAHYETTGPEILKEV-----KDVSFIVAGIG 178

Query: 233 GGSNAIGMFADFINETN--VGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTE 290
            G   +G    F+ E N  + +IG+EP    + T     P K   +G  F    P +  +
Sbjct: 179 SGGTIVG-AGKFLKEKNKEIKVIGIEPKSSPLITENKSGPHKIQGIGANF---IPKIYDK 234

Query: 291 DGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALE 350
           D  I +                            ++++D+++ E  + +    GI+  + 
Sbjct: 235 D--IVD--------------------------KVITVSDEDSYETVRLIANKLGILIGIS 266

Query: 351 SSHALAHALKMMRENPDKEQLLVVNLSGRG 380
           S   +  A+K+  ENPDK   ++V ++  G
Sbjct: 267 SGANIFGAMKLSDENPDK---IIVTVAPDG 293


>UniRef50_Q9Y9K2 Threonine synthase n=1 Tax=Aeropyrum pernix RepID=Q9Y9K2_AERPE
          Length = 393

 Score = 75.7 bits (185), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 66/332 (19%), Positives = 120/332 (36%), Gaps = 37/332 (11%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T L K +N++      +Y K E L   G+ K   +     +A       ++A +  G   
Sbjct: 59  TPLVKLENLSRAMGVEVYGKLEFLNPTGSFKDRGMTVGVSIASSFSYRLVVAAS-TGNTA 117

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD 176
            + A  +   GL   I +    +     +   +  +GA V+ V        DA   A   
Sbjct: 118 ASMAAYARRAGLNPVILIPKGGIASGKLSQ--IAALGAWVLEVEGSFDDALDAARAAAEK 175

Query: 177 WSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSN 236
                    Y L +   P+       E Q+ I  E    +   +  +       VG   N
Sbjct: 176 GLA------YSLNS-INPYR-----LEGQKTIAFEILEDVDRVDHVV-----VPVGNAGN 218

Query: 237 AIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHG---RVGIYFGMKAPMMQTEDGQ 293
              ++  F     +GL  + P   G+   E  +PL      ++     ++ P       +
Sbjct: 219 ISAIWKGFKEAGLLGLPSMRPRMVGV-QAEGASPLYRAWVEKMDSVERVRNPSTIASAIR 277

Query: 294 IEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSH 353
           I    + +  L         A   S G    +S++D E L+A  TL  +EG++    S+ 
Sbjct: 278 IGNPVNAAKAL--------AAVRESDGLI--ISVSDAEILKAAATLAENEGMLVEPASAA 327

Query: 354 ALAHALKMMREN--PDKEQLLVVNLSGRGDKD 383
           +LA  +K+  +        ++++ L+G G KD
Sbjct: 328 SLAGLIKLRNQGIIASGSSVVLI-LTGHGLKD 358


>UniRef50_A6C9B2 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit n=1
           Tax=Planctomyces maris DSM 8797 RepID=A6C9B2_9PLAN
          Length = 326

 Score = 75.7 bits (185), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 49/206 (23%), Positives = 76/206 (36%), Gaps = 26/206 (12%)

Query: 56  PTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           PT L +   ++  T T L+LK E+    GA K    +          +   I     G H
Sbjct: 22  PTPLIEWPGLSRLTGTQLFLKHENHQPVGAFKVRGGINLVSTLSEEERQAGIMGCSTGNH 81

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
           G + A A+   G+KC I +           V  +R++GAE+I          +  NEA +
Sbjct: 82  GQSLAFAARKYGVKCTIVVPR---NNNPDKVEAIRMLGAEIIEA-------GEDFNEAKQ 131

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRL--PDAVIACVGG 233
                            G   Y     E + + G     Q +E    L  PD ++  VG 
Sbjct: 132 YLEEQLID---------GKRRYVHSANEPKLIAG--VGTQGIEIFDTLPNPDVILVPVGM 180

Query: 234 GSNAI--GMFADFINETNVGLIGVEP 257
           GS     G+ A ++      +IGV+ 
Sbjct: 181 GSGVCGTGIVARYMR-PQTEVIGVQA 205


>UniRef50_Q2IRQ4 L-threonine synthase n=1 Tax=Rhodopseudomonas palustris HaA2
           RepID=Q2IRQ4_RHOP2
          Length = 420

 Score = 75.3 bits (184), Expect = 4e-12,   Method: Composition-based stats.
 Identities = 69/339 (20%), Positives = 119/339 (35%), Gaps = 46/339 (13%)

Query: 57  TALTKCQNITAGTNTT-LYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           + L + + +        LY K E      + K         +AK+MG   I++ +     
Sbjct: 82  SPLRQLRAVGDQLGLKRLYGKDESGNPTWSFKDRLACIAVSVAKQMGAKTIVSSSSGNA- 140

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
           G A+A  +A  G+ C ++          P V +MR  GA+V+ V       +     A+R
Sbjct: 141 GAAAAAYAAKAGIPCVVF---TFGWAAGPMVTQMRAYGAKVVTVPQKEDRWR-FMEHAVR 196

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
            +     +  +  G A G +PY     E  + +  ET  Q+     R PD  I  V  G 
Sbjct: 197 QYGWFPTSPFF--GPAVGSNPYG---IEGYKTLAYETVEQL---GWRAPDWCILPVCYGD 248

Query: 236 NAIGMFADFIN-------ETNVGLIGVE---PGGHGIETGEHGAPLKHGRVGIYFGMKAP 285
             IGM+  F         +    ++  E     G  ++      P          G    
Sbjct: 249 ALIGMWRGFTEMKAAGWIDRMPKMVAAEVYGSIGRALDDDLEAPPAMPKTFDTVSGSI-- 306

Query: 286 MMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGI 345
                 G ++ +Y                   S GRA  V+I++D+ +   + L   E  
Sbjct: 307 ------GAVQGTYQ-----------ALEIVRKSGGRA--VTISNDDTMRWQRLLATREAR 347

Query: 346 IPALESSHALAHALKMMRENPDK-EQLLVVNLSGRGDKD 383
                S+  L    ++ +    K + ++V  L+  G KD
Sbjct: 348 YLEPASAGGLVAVERLAKSGIIKPDDVVVSLLTASGLKD 386


>UniRef50_Q97CB2 Threonine deaminase n=4 Tax=Thermoplasmatales RepID=Q97CB2_THEVO
          Length = 406

 Score = 75.3 bits (184), Expect = 4e-12,   Method: Composition-based stats.
 Identities = 67/346 (19%), Positives = 114/346 (32%), Gaps = 48/346 (13%)

Query: 36  QKDPEFQA--QFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLG 93
            + P F    +    L+    R T L +   I       +Y K E+    G+ K+   + 
Sbjct: 4   LEIPSFDEIIEAQRYLEGKVNR-TPLIRSTTIGKEYGADIYFKLENFQKTGSFKSRGAIF 62

Query: 94  QALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMG 153
           +        K   +    AG H    A A+ + G+  +I M    + ++   V      G
Sbjct: 63  RFSKLSEDEKRHGVITASAGNHAQGVAYAAMINGIDAKIVMPEYTIPQKVNAVI---SYG 119

Query: 154 AEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETK 213
           A VI   S         +EA R      +      G           V   Q  IG E  
Sbjct: 120 AHVILKGS-------DYDEAHRYADEIAKQE----GRIFIEAFNDRWVISGQGTIGLEIM 168

Query: 214 AQILEREGRLPDAVIACVGGGSNAIGMF-ADFINETNVGLIGVEPGGHGIETGEHGAPLK 272
             +        D ++  VGGG    G+  A       V +IG+E       +    A L+
Sbjct: 169 EDLP-----DVDIILVPVGGGGLISGIALAAKHASNKVKVIGIE----SELSDSMKASLR 219

Query: 273 HGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRA---DYVSITD 329
            G++         +  T    I +  S+     +P V           R    D V++T+
Sbjct: 220 EGKI---------VAHTSGVSICDGISV----KYPGV-----LTFDIARKYVDDIVTVTE 261

Query: 330 DEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVN 375
           +   +A   L     I+     +  LA  ++   +   K+  +VV+
Sbjct: 262 EYVSKAIYKLFERNKIVAEPSGAVGLAAIMEGKVDVKGKKVAIVVS 307


>UniRef50_D2S288 Threonine dehydratase n=2 Tax=Haloterrigena turkmenica DSM 5511
           RepID=D2S288_9EURY
          Length = 414

 Score = 75.3 bits (184), Expect = 4e-12,   Method: Composition-based stats.
 Identities = 59/310 (19%), Positives = 100/310 (32%), Gaps = 40/310 (12%)

Query: 33  VSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVL 92
            S  +  + +   +        + T + +  ++    +  +YLK E L   G+ KT    
Sbjct: 8   ESLVQYADIERARDRFDDETVVKRTPVERSTSLGEMVDAEVYLKMEHLQWTGSFKTRGAY 67

Query: 93  GQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLM 152
            +   A   G  E +A + AG H    ALA+   G    I M     + +       R  
Sbjct: 68  NKIRQAVDDGADEFVAAS-AGNHAQGVALAATKCGANSTIVMPTHAPQAKIDAT---RSY 123

Query: 153 GAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEET 212
           GA V  V       ++A   A +D++   +            +  P IV   Q  +G E 
Sbjct: 124 GAAVELV---GQDFQEAMAYA-QDYAADNDVEF------VHAYDDPNIVA-GQGTLGIEI 172

Query: 213 KAQILEREGRLPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPL 271
                       D V+  +GGG    G+     +      ++GV+  G           L
Sbjct: 173 HEDCP-----DVDTVVVPIGGGGLISGVATALDHLSPETRVVGVQAEG----AATVHESL 223

Query: 272 KHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDE 331
             G          P+   E   I +   I+ G     +      L      + V+++D E
Sbjct: 224 DKG---------IPVTLDEVDTIADG--IATG----GISDLTLNLIEDHVDEVVTVSDAE 268

Query: 332 ALEAFKTLCL 341
              A   L  
Sbjct: 269 IANAILLLLE 278


>UniRef50_Q5WLV3 Cysteine synthase n=48 Tax=Bacteria RepID=Q5WLV3_BACSK
          Length = 312

 Score = 75.3 bits (184), Expect = 4e-12,   Method: Composition-based stats.
 Identities = 58/324 (17%), Positives = 114/324 (35%), Gaps = 54/324 (16%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE---IIAETGAG 113
           T L K   +    +  +YLK E    G + K    L     A+  G+ +    I E  +G
Sbjct: 14  TPLVKLNRLATAEHADVYLKLEYQNPGSSVKDRIALAMVNAAEESGELKPGATIVEPTSG 73

Query: 114 QHGVASALASALLGLKCRIYMGAK-DVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNE 172
             G+  A+ +A  G K ++ M     +ER       +R  GAE++    G   +  A  +
Sbjct: 74  NTGIGLAMVAAAKGYKTKLVMPETMSMER----RNLLRAYGAELVLTP-GPEGMGGAIRK 128

Query: 173 ALRDWSGSYETAHYMLGTAAGPHPYPTIV--REFQRMIGEETKAQILEREGRLPDAVIAC 230
           A      + +  H+M      P  +      +  +   G+E   Q+  +       +   
Sbjct: 129 ATEL---AKQDGHFM------PQQFENSANPKIHRETTGKELLKQVDGQLDGFVAGIGTG 179

Query: 231 VGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTE 290
                    +   F     + ++ +EP    + +G    P  H   GI  G    ++ T 
Sbjct: 180 GTITGAGGLLKEHF---PELKIVAIEPKDSPVLSGGKPGP--HKLQGIGPGFVPGILNTN 234

Query: 291 DGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALE 350
                          + SV               + ++ ++A E  +     EGI+  + 
Sbjct: 235 V--------------YDSV---------------LQVSTEQAFEYARRAAREEGILGGIS 265

Query: 351 SSHALAHALKMMRENPDKEQLLVV 374
           S  A+  AL++ +E    ++++ +
Sbjct: 266 SGAAIYGALELAKELGPGKKVVAI 289


>UniRef50_Q93968 Protein T01H8.2, confirmed by transcript evidence n=5
           Tax=Caenorhabditis RepID=Q93968_CAEEL
          Length = 317

 Score = 75.0 bits (183), Expect = 4e-12,   Method: Composition-based stats.
 Identities = 73/323 (22%), Positives = 121/323 (37%), Gaps = 55/323 (17%)

Query: 68  GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLG 127
           G  T +  K E L   G+ K    L  A+LAK      +IA + +G HG A A A+  +G
Sbjct: 37  GNGTHVLFKCEHLQKTGSFKARGALNSAILAKEKNAKGMIAHS-SGNHGQALAWAAQKIG 95

Query: 128 LKCRIYMGAKDVERQSPNVFRMRLMGAEVI---PVHSGSATLKDACNEALRDWSGSYETA 184
           L C I +       +   +  MR   A ++   P  +   ++     E L          
Sbjct: 96  LPCTIVVPKNAPISK---IEGMREYNANIVFCEPTVTSRESVCADLTEKLE--------- 143

Query: 185 HYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGG---SNAIGMF 241
           +Y       P+   +++     +  E     ILE+ G   D++   VGGG   S+   + 
Sbjct: 144 YYC----VEPYNCVSMINGHSSVAFE-----ILEQVGNEIDSIFLSVGGGGLASSVAFLI 194

Query: 242 ADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSIS 301
            +   +  V L  V+P    +               +  G+K P+  T D       +I+
Sbjct: 195 GNLRPDIEVYL--VQPAQKELSNF------------LENGIKCPV-DTLD-------TIA 232

Query: 302 AGLDFPSVGPQ-HAYLNSTGRADYVSITDDEALEAFKTL-CLHEGIIPALESSHALAHAL 359
            G+    VGP     L        +S+ +DE  E  K +    +  I   E + ALA A 
Sbjct: 233 DGVRVARVGPLCEPILKQYCAQKVISVKEDEIKEGLKLIWTRMKQRI---EPTAALAFAG 289

Query: 360 KMMRENPDKEQLLVVNLSGRGDK 382
            +  +    ++ LV+   G  D 
Sbjct: 290 VLYHKPAHIKRPLVILCGGNVDT 312


>UniRef50_D0L0K6 Threonine synthase n=20 Tax=Gammaproteobacteria RepID=D0L0K6_HALNC
          Length = 395

 Score = 75.0 bits (183), Expect = 4e-12,   Method: Composition-based stats.
 Identities = 64/352 (18%), Positives = 107/352 (30%), Gaps = 55/352 (15%)

Query: 57  TALTKCQNITAGTNT--TLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQ 114
           T L +  NI         +Y+K E L   G+ K   +      A   G   +I  +  G 
Sbjct: 42  TPLIRLNNIPRVLGCSLDIYVKYEGLNPTGSFKDRGMTMAVTKAVEAGSKAVICAS-TGN 100

Query: 115 HGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEAL 174
              ++A  +A  G+   + +    +         M   GA  + +           ++ +
Sbjct: 101 TSASAAAYAARAGITAFVLIPDGKIAMGKLAQAMM--YGATTLQIRGN-------FDDGM 151

Query: 175 RDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGG 234
           R      + A   +  +  P        + Q+    E    I+E  GR PD     VG  
Sbjct: 152 RLVKEVADHAPVTIVNSVNPFR-----LQGQKTAAFE----IIEELGRAPDFHCLPVGNA 202

Query: 235 SNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKA---PMMQTED 291
            N    +  +           E      +          G      G      P M    
Sbjct: 203 GNITAHWIGY----------CESSASHGDNLTESCAFCDGNCAFVKGAACTNRPKMIGYQ 252

Query: 292 GQIEESYSISAGLDFPSVGPQHAYLNSTGRAD---------------YVSITDDEALEAF 336
                 +   A +D P      A     G                  +  +TD E L A 
Sbjct: 253 ASGSAPFIRGAMVDHPE---TLATAIRIGHPQSWDRAWKVMSESGGWFAEVTDTEILAAQ 309

Query: 337 KTLCLHEGIIPALESSHALAHALK--MMRENPDKEQLLVVNLSGRGDKDIFT 386
           + L +HEGI     S+ +LA  +      + P+   +++  L+G G KD  T
Sbjct: 310 RMLTMHEGIFCEPASAASLAGLINDVKAGKIPEGSSVVL-TLTGNGLKDPDT 360


>UniRef50_B5YF95 Threonine dehydratase n=2 Tax=Dictyoglomus RepID=B5YF95_DICT6
          Length = 406

 Score = 75.0 bits (183), Expect = 4e-12,   Method: Composition-based stats.
 Identities = 66/341 (19%), Positives = 121/341 (35%), Gaps = 54/341 (15%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T ++  Q  +  T   ++LK E+L   GA K    +    +++      +I  + AG H 
Sbjct: 21  TPISLSQTFSDMTGKEIFLKFENLQKTGAFKIRGAIN--YISQLKKVKGVITAS-AGNHA 77

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD 176
              A AS L G+   I M       +  +    +  GA+VI          DA N A   
Sbjct: 78  QGVAYASKLFGIPSTIVMPENTPLIKIIST---KNYGAKVIL---HGKVYDDAFNYAKE- 130

Query: 177 WSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSN 236
              + E   ++      P      +   Q  I  E    + + E     A+I  +GGG  
Sbjct: 131 -LANEERLEFV------PAFDDERIISGQGTIALEILEDLKDIE-----ALIVPIGGGGL 178

Query: 237 AIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQI- 294
           A G+          + + GV+                            P M  +  ++ 
Sbjct: 179 ASGILIALKEINPKIKVYGVQSNAF------------------------PSMYEKIKKVE 214

Query: 295 ---EESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALES 351
              +   +I+ G+     G   +++      D   + +++  EA   L      +     
Sbjct: 215 IPKKPEQTIAEGIAVKKPGEITSHIIEKYIDDIFIVEEEKIAEAILLLLERAKTLVEGAG 274

Query: 352 SHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILK 392
           +  LA  LK   + P+K+ +L+  LSG G+ D+  +  I++
Sbjct: 275 ASTLAAVLKYCDQIPEKKIVLI--LSG-GNIDVSLLTKIIE 312


>UniRef50_Q2PGG3 Serine racemase n=18 Tax=cellular organisms RepID=Q2PGG3_ARATH
          Length = 331

 Score = 75.0 bits (183), Expect = 4e-12,   Method: Composition-based stats.
 Identities = 50/235 (21%), Positives = 94/235 (40%), Gaps = 25/235 (10%)

Query: 28  LEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHK 87
           +E        D     + +D +K Y  R T +   +++ + +  +L+ K E L  GGA K
Sbjct: 1   MEANREKYAADILSIKEAHDRIKPYIHR-TPVLTSESLNSISGRSLFFKCECLQKGGAFK 59

Query: 88  TNQVLGQAL-LAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNV 146
                   L L        ++  + +G H  A +LA+ + G+   I +     + +  NV
Sbjct: 60  FRGACNAVLSLDAEQAAKGVVTHS-SGNHAAALSLAAKIQGIPAYIVVPKGAPKCKVDNV 118

Query: 147 FRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPY-PTIVREFQ 205
            R    G +VI   +  ++ ++  ++ L++            G+    HPY    +   Q
Sbjct: 119 IR---YGGKVIWSEATMSSREEIASKVLQE-----------TGSVL-IHPYNDGRIISGQ 163

Query: 206 RMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGG 259
             I  E   QI E      DA++  + GG    G+     + + ++ +I  EP G
Sbjct: 164 GTIALELLEQIQEI-----DAIVVPISGGGLISGVALAAKSIKPSIRIIAAEPKG 213


>UniRef50_B3EGT7 Cysteine synthase A n=8 Tax=Bacteria RepID=B3EGT7_CHLL2
          Length = 309

 Score = 75.0 bits (183), Expect = 4e-12,   Method: Composition-based stats.
 Identities = 75/335 (22%), Positives = 119/335 (35%), Gaps = 58/335 (17%)

Query: 53  AGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK----TEIIA 108
            GR T L +   ++ G    + +K E      + K    +     A++ G     T +I 
Sbjct: 11  VGR-TPLVRLHRLSRGCRADVLVKIESFNPLSSVKDRIAVAMLEDAEKSGMIVPGTTLIE 69

Query: 109 ETGAGQHGVASALASALLGLKCRIYMGAK-DVERQSPNVFRMRLMGAEVIPVHSGSATLK 167
            T +G  G+  A A A  G +  + M     +ER       M+ +GAE++    GS  + 
Sbjct: 70  PT-SGNTGIGLAFACAAKGYRLMLVMPDTMSIER----RKLMQFLGAELVLTE-GSGGMN 123

Query: 168 DACNEALRDWSGSYETAHYMLGTAAGPH-PYPTIVREFQRMIGEETKAQILEREGRLPDA 226
            A  EA R        A  + G+        P      +      T  +I E  G + D 
Sbjct: 124 RAIAEAERL-------AESIPGSLILQQFRNPANPAVHR----LTTAVEIWEDSGGMVDV 172

Query: 227 VIACVGGGSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAP 285
            +A VG G    G+  +       V +I VEP             L  G+ G        
Sbjct: 173 FVAGVGTGGTITGVGEELKKHKPGVAIIAVEP--------YDSPVLSGGQPG-------- 216

Query: 286 MMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGI 345
                       + I         G   A LN     + V +T+++A    + L   EGI
Sbjct: 217 -----------PHKIQG----IGAGFVPAILNREIIDEIVKVTNEDAGATARRLAAEEGI 261

Query: 346 IPALESSHALAHALKMMR--ENPDKEQLLVVNLSG 378
           +  + S  AL  AL + R  E   K  ++++  SG
Sbjct: 262 LCGISSGAALYAALGIARREEMEGKMVVVLLPDSG 296


>UniRef50_D1CAF5 Pyridoxal-5'-phosphate-dependent protein beta subunit n=1
           Tax=Sphaerobacter thermophilus DSM 20745
           RepID=D1CAF5_SPHTD
          Length = 395

 Score = 75.0 bits (183), Expect = 5e-12,   Method: Composition-based stats.
 Identities = 67/348 (19%), Positives = 119/348 (34%), Gaps = 54/348 (15%)

Query: 48  LLKNYAGRPTALTKCQNITAG---------TNTTLYLKREDLLHGGAHKTNQVLGQALLA 98
           L +  A  P  L   + +  G             +  K + LL  G+ K           
Sbjct: 72  LWRYRAILPVPLEAARPLGEGMTPLVPGTLLGRRVLFKLDGLLPTGSFKDRGAAVLVAHL 131

Query: 99  KRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIP 158
           +R+G+  II ++ +G    A A  SA  GL C +Y            + + R  GA V+P
Sbjct: 132 RRLGRQRIIVDS-SGNAAAAMAGYSAAAGLACTVY---APASASPGKLVQSRAYGATVVP 187

Query: 159 VHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILE 218
           V       ++A   A +  +    +A Y        H +  +  E  +    E   Q+ +
Sbjct: 188 VEGN----REAVAAAAQQAAADDPSAFYA------SHNWHPVFVEGVKTWLLEVWEQLGQ 237

Query: 219 REGRLPDAVIACVGGGSNAIGMFADF--INETNVGLIGVEPGGHGIETGEHGAPLKHGRV 276
           +   LP A     GGGS  IG +     +      L+  +P           A       
Sbjct: 238 Q---LPAACFIPTGGGSALIGAWRATTALPGPAPALVAAQPAACAPLVAAVQAS------ 288

Query: 277 GIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVG---PQHAYLNSTGRADYVSITDDEAL 333
                       TE   I    +I+ G    +        A +  TG     ++ ++E +
Sbjct: 289 ------------TEVTPITPGDTIAEGTRIGAPARPRQMLAAVRETG-GWAEAVPEEEIV 335

Query: 334 EAFKTLCLHEGIIPALES---SHALAHALKMMRENPDKEQLLVVNLSG 378
            A + L   +G+     +   + A   A++     P+ E ++++  SG
Sbjct: 336 AALREL-WGQGLYVEPTAAVGAAAFRQAVRRGHPIPEGEVVVLLTGSG 382


>UniRef50_C4LUI9 Threonine dehydratase, putative n=4 Tax=Entamoeba
           RepID=C4LUI9_ENTHI
          Length = 429

 Score = 75.0 bits (183), Expect = 5e-12,   Method: Composition-based stats.
 Identities = 62/330 (18%), Positives = 114/330 (34%), Gaps = 54/330 (16%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T L    +I+A     +Y K E++   G+ K   V+ +        K   +    +G HG
Sbjct: 51  TPLDSNASISADIGMDVYFKLENMQKSGSFKVRGVMNKFNSLTLAEKKRGVIAASSGNHG 110

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVI----PVHSGSATLKDACNE 172
           +A A     LG+   I +              M+  GA VI     V    A  K+   E
Sbjct: 111 MAVAYCGKQLGVPTTIIVPNFT---NPRRAETMKRYGATVILHGVTVAEAEAYAKEMSTE 167

Query: 173 ALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVG 232
               +  + +    + G                  +G E    +        DA+IA +G
Sbjct: 168 KRLAYIEARDDVSIIAGDG---------------TVGLEILRDLP-----DVDAIIAPIG 207

Query: 233 GGSNAIGMFADFIN-ETNVGLIGV--EPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQT 289
            GS   G+       +  V + GV  E G     + +H              +     Q 
Sbjct: 208 SGSLLCGLALAVKTLDPRVKVYGVQNEKGSSAYLSKKHH-------------VLCRTHQN 254

Query: 290 EDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPAL 349
           ED ++ +  +    L    +    +Y++       +++ + +   A   L     +I  +
Sbjct: 255 EDNELTDVVNTIGNLTLHMIE---SYVDDI-----ITVDETQITRAMMLLMERCKVI--I 304

Query: 350 ESSHALAHALKMMRENP-DKEQLLVVNLSG 378
           E + A+A A  + ++ P +K   + V +SG
Sbjct: 305 EGAGAVALAGLLSKKLPIEKGSKVAVIVSG 334


>UniRef50_C4Z926 Threonine dehydratase n=58 Tax=Bacteria RepID=C4Z926_EUBR3
          Length = 416

 Score = 74.6 bits (182), Expect = 7e-12,   Method: Composition-based stats.
 Identities = 75/339 (22%), Positives = 124/339 (36%), Gaps = 48/339 (14%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQA-LLAKRMGKTEIIAETGAGQH 115
           T L     ++  T   +YLK E++   GA+K      +   L        +I  + AG H
Sbjct: 34  TKLIYSDFLSDQTGNKVYLKPENMQFTGAYKVRGAYYKISTLTDEERAKGLITAS-AGNH 92

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
               A A+   G K  I M           V R +  GAEV+          D  +EA  
Sbjct: 93  AQGVAYAAKCYGCKAVIVMPTTTP---LIKVNRTKSYGAEVVL-------YGDVYDEACA 142

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTI-VREFQRMIGEETKAQILEREGRLPDAVIACVGGG 234
                 E   Y        HP+  + V   Q  I  E   ++      L + ++  +GGG
Sbjct: 143 KAYELAEKEGYTF-----IHPFDDLAVATGQGTIAMEIFKELP-----LVEYILVPIGGG 192

Query: 235 SNAIGMFA-DFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQ 293
             A G+     +    + +IGVEP G            K+G+V     +        DG 
Sbjct: 193 GLATGVSTLAKLLNPKIKVIGVEPAGANCMQE----SFKNGKVTTLPSVNTI----ADGT 244

Query: 294 IEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSH 353
             ++            G            D +++ DDE + AF  +  +  +I   E+S 
Sbjct: 245 AVKTP-----------GSNIFPYIKKNLDDIITVEDDELIVAFLDMVENHKMIV--ENSG 291

Query: 354 ALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILK 392
            L  A   ++    K++ +V  LSG G+ D+ T+  +++
Sbjct: 292 LLTVAA--LKHLGVKDKRVVSILSG-GNMDVITMSSVVQ 327


>UniRef50_C6C043 Cysteine synthase n=5 Tax=Bacteria RepID=C6C043_DESAD
          Length = 764

 Score = 74.2 bits (181), Expect = 8e-12,   Method: Composition-based stats.
 Identities = 61/296 (20%), Positives = 100/296 (33%), Gaps = 57/296 (19%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK---TEIIAETGAG 113
           T L + + +    N  +  K E +  GG+ K          A++ G+    +II E  +G
Sbjct: 13  TPLVEMRVLNPNKNVKILAKLEAMNPGGSIKDRAAGAMIRKAEKSGELTPDKIIIEATSG 72

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
             G+  A+A A+ G K  + M     E        MR  GAE++      AT   A  +A
Sbjct: 73  NTGIGLAMACAVRGYKLMLIMPETASEE---RKMIMRAYGAEIMLTPGHLAT-DGAIEQA 128

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
            R +    E   Y+L      +     +       G+E   Q           V+AC+G 
Sbjct: 129 YRFYREEPE--KYLL---MDQYNNEASIDAHYEGTGQEIWDQ----TEGKVTHVVACLGT 179

Query: 234 GSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGI-YFGMKAPMMQTED 291
               +G+         ++ +I VEP                   G    G+K   MQ   
Sbjct: 180 TGTVMGITKRLKELNKDIQMIAVEP-----------------EPGHKIQGLKN--MQES- 219

Query: 292 GQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIP 347
                         +P   P         R   + + D++A E+ + L   EG+  
Sbjct: 220 --------------YP---PGIYDKQKLDRV--IRVQDNDAFESCRRLAKEEGVFV 256


>UniRef50_Q5HMF5 Threonine dehydratase biosynthetic n=12 Tax=Bacteria
           RepID=THD1_STAEQ
          Length = 422

 Score = 74.2 bits (181), Expect = 8e-12,   Method: Composition-based stats.
 Identities = 68/342 (19%), Positives = 121/342 (35%), Gaps = 44/342 (12%)

Query: 55  RPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQ 114
           + T L     ++   N  +YLKREDL    + K         +     K + I    AG 
Sbjct: 24  KETPLQFDHYLSQKYNCNVYLKREDLQWVRSFKLRGAYNAISVLSNEEKNKGITCASAGN 83

Query: 115 HGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMG-AEVIPVHSGSA---TLKDAC 170
           H    A  +  L LK  I+M      ++   V   +  G + V  V  G      L  A 
Sbjct: 84  HAQGVAYTAKKLNLKAVIFMPVTTPRQKINQV---KFFGDSNVEIVLIGDTFDHCLAQAL 140

Query: 171 NEALRDWSGSYETAHYMLGTAAGPHPYPTI-VREFQRMIGEETKAQILEREGRLPDAVIA 229
           N     ++  ++             P+  +     Q  + +E   Q  E+E +  D V A
Sbjct: 141 N-----YTKQHKMNF--------IDPFNNVYTIAGQGTLAKEILNQA-EKEDKTFDYVFA 186

Query: 230 CVGGGSNAIGMFADF-INETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQ 288
            +GGG    G+   F  +  +  +IGVEP G         A   +  V I   +      
Sbjct: 187 AIGGGGLISGVSTYFKAHSPHTKIIGVEPTG---------ASSMYQSVVINHSIVTLENI 237

Query: 289 TEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPA 348
            +     +  S++       VG     +      DYV + +         +   + I+  
Sbjct: 238 DK---FVDGASVAR------VGDITFDIAKDKVDDYVQVDEGAVCSTILDMYSKQAIVAE 288

Query: 349 LESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDI 390
              + +++   +  ++  +K  + +V  SG G+ DI  + +I
Sbjct: 289 PAGALSVSALEQYKKQIENKTIVCIV--SG-GNNDINRMKEI 327


>UniRef50_A9M562 Threonine dehydratase n=47 Tax=Alphaproteobacteria
           RepID=A9M562_BRUC2
          Length = 419

 Score = 74.2 bits (181), Expect = 9e-12,   Method: Composition-based stats.
 Identities = 36/173 (20%), Positives = 62/173 (35%), Gaps = 14/173 (8%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETG-AGQH 115
           T L +   ++      ++LKREDL    ++K          A        +     AG H
Sbjct: 23  TPLQRNDYLSRKYGAQIWLKREDLTPVRSYKLRGAFNFISKAVETTDKNAVFVCASAGNH 82

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
               A      G K  ++M     +++       R  G E I +        D C  A +
Sbjct: 83  AQGFAFVCRHFGRKGVVFMPVTTPQQKIDKT---RTFGGEFIEIKLVGDIF-DVCYAASQ 138

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVI 228
           +++ + +      G    P  +P IV E Q  +  E + Q+ +     PD V+
Sbjct: 139 EFAAANK------GVMVPPFDHPGIV-EGQATVALEIERQLPD--DSKPDLVL 182


>UniRef50_UPI0001903713 tryptophan synthase subunit beta n=1 Tax=Rhizobium etli Brasil 5
          RepID=UPI0001903713
          Length = 69

 Score = 74.2 bits (181), Expect = 9e-12,   Method: Composition-based stats.
 Identities = 20/53 (37%), Positives = 32/53 (60%)

Query: 6  NPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTA 58
          +  FG +GG +V + LMP +  L++ +  A+ DP FQA+   L  +Y GRP+ 
Sbjct: 17 DGRFGIYGGRFVAETLMPLILDLQDEWNKAKTDPAFQAELKHLGAHYIGRPSP 69


>UniRef50_Q88I11 Threonine dehydratase family protein n=43 Tax=cellular organisms
           RepID=Q88I11_PSEPK
          Length = 350

 Score = 73.8 bits (180), Expect = 9e-12,   Method: Composition-based stats.
 Identities = 77/349 (22%), Positives = 121/349 (34%), Gaps = 46/349 (13%)

Query: 38  DPEFQAQFNDLLKNY--AGRP----TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQV 91
           D +F    +  +++   A RP    T L     ++A T   + LK E L H G+ K    
Sbjct: 29  DAQFLDTLHQNIQDAHAALRPAVSITPLLHSPRLSALTGCEVLLKCEHLQHTGSFKFRGA 88

Query: 92  LGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRL 151
             +  L     + + +    +G HG A ALA  + G+  ++Y         +     MR 
Sbjct: 89  SNKMRLLPAEARKQGVIAASSGNHGQALALAGKMAGVPVKVY---TTTGASAYKTEAMRA 145

Query: 152 MGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEE 211
           +GAEV+ + +   +   A  EA R             G           V   Q  IG E
Sbjct: 146 LGAEVVCLPTDPLS---AELEAARQAKAQ--------GVPFVSPYNDLQVIAGQGTIGME 194

Query: 212 TKAQILEREGRLPDAV-IACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAP 270
              Q  +      DAV +A  GGG  +    A  + +    +IG  P             
Sbjct: 195 LLEQAPDL-----DAVFVAVGGGGMISGIGAALRVLKPGTEIIGCWPANDPTLQQ----S 245

Query: 271 LKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDD 330
           LK G   I        +        E  SI+    FP        L      D V +++D
Sbjct: 246 LKAGE--IIELDACETLSDGTAGGVEPGSIT----FP--------LCQALLTDTVLVSED 291

Query: 331 EALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGR 379
           E   A + +   E  I    ++ A+A   ++      K   ++  L GR
Sbjct: 292 EIRCAMRDIASSERWIIEGAAAVAVAGMQRLAERYQGKRVAVI--LCGR 338


>UniRef50_Q1AYU1 Cysteine synthase n=5 Tax=Bacteria RepID=Q1AYU1_RUBXD
          Length = 327

 Score = 73.8 bits (180), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 72/312 (23%), Positives = 111/312 (35%), Gaps = 46/312 (14%)

Query: 73  LYLKREDLLHGGAHKTNQVLGQALLAKRMGK---TEIIAETGAGQHGVASALASALLGLK 129
           +Y K E L   G+ K          A+R G       I E  +G  G A ++ +A+ G +
Sbjct: 37  IYAKLEYLNPSGSIKARIARYIVEKAEREGLLLPGHTIVEATSGNTGNAFSMVAAIKGYR 96

Query: 130 CRIYMGA-KDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYML 188
             + M      ER    V   R  GA +  V  G   + +A   A R+        ++  
Sbjct: 97  MVVLMPEGLSTER----VAISRAFGAHIEHV--GEFYVTEALKRA-RELGKK--EGYFCP 147

Query: 189 GTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFIN-E 247
                       V E +  +G+E   Q+ E     PDA++  VG G   IG+   F    
Sbjct: 148 ----AQFDSEWNVEENREWLGKEILGQLEEGGVGAPDALVMGVGTGGTLIGVGQAFREKN 203

Query: 248 TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFP 307
               LI VEP        E    L  G  G+            +G       IS G   P
Sbjct: 204 AEAKLIAVEP--------EESCTLLCGESGV---------HKIEG-------ISDGF-VP 238

Query: 308 SVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPD 367
            +  +HA     G  +  ++  +EAL A + L    G+     S   L  A ++   +P+
Sbjct: 239 GIYERHA--ERLGVDEVYAVGSEEALGAMRWLARRRGLFVGPSSGANLVAARRLKEAHPE 296

Query: 368 -KEQLLVVNLSG 378
            K  + +    G
Sbjct: 297 LKSIVTLFCDEG 308


>UniRef50_C9NEG9 Cysteine synthase n=1 Tax=Streptomyces flavogriseus ATCC 33331
           RepID=C9NEG9_9ACTO
          Length = 379

 Score = 73.8 bits (180), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 71/344 (20%), Positives = 124/344 (36%), Gaps = 60/344 (17%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK----TEIIAETGA 112
           T L +   +  G    ++ K E +  GG+ K          A   G     T  + E+ +
Sbjct: 51  TPLVELTRLLPGARFRVWAKLESVSPGGSIKDRSAYTMLSHAVATGAVVPGTGTVVESSS 110

Query: 113 GQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKD--AC 170
           G  GV  A     + L+   ++   D      N+  MR +GAEV  V  G     +    
Sbjct: 111 GNLGVGMAQMCRAMDLR---FICVVDPRTNPQNIAIMRALGAEVHTVDEGDPVTGEFQPV 167

Query: 171 NEA-LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIA 229
             A +R+   +   A++        +  P      +  + E     I+E  G+ PD +  
Sbjct: 168 RIARVRELVAAVPGAYWP-----NQYANPRNAWAHRITMTE-----IVEDLGQAPDYLF- 216

Query: 230 CVGGGSNAIGMFADFINETNV--GLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMM 287
           C    S  +    D I +  +   +I V+  G  I        L  G             
Sbjct: 217 CTISSSGTLRGCGDLIRDHRLPTRVITVDAEGSAIFRPPTARRLIPG------------- 263

Query: 288 QTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRA-DYVSITDDEALEAFKTLCLHEGII 346
                         A +  P        L   G A + V ++D ++L   + L L EG++
Sbjct: 264 ------------HGAAVRPP--------LYRGGLADEVVHVSDLDSLVGCRRLALREGLL 303

Query: 347 PALESSHALAHAL-KMMRENPDKEQLLVVNLSGRGDKDIFTVHD 389
               SS A+A AL ++    PD    +++ +  RG++ + T++D
Sbjct: 304 LG-GSSGAVATALERLSGRIPDGSSCVLL-MPDRGERYLNTIYD 345


>UniRef50_B9L1A5 Threonine ammonia-lyase, biosynthetic n=2 Tax=Thermomicrobia
           (class) RepID=B9L1A5_THERP
          Length = 341

 Score = 73.8 bits (180), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 49/213 (23%), Positives = 77/213 (36%), Gaps = 30/213 (14%)

Query: 56  PTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG---KTEIIAETGA 112
           PT L     ++      +YLK E L   GA K     G   L  ++    +   +     
Sbjct: 31  PTPLLHSPLLSERLGCQVYLKCEQLQPIGAFKVR---GGIYLMSKLSPEERARGVVTAST 87

Query: 113 GQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNE 172
           G HG + A A+ L G++  IY            V  MR +GAEV+         + AC  
Sbjct: 88  GNHGQSIAYAARLFGVRAIIYAPE---GANPLKVAAMRRLGAEVVLTGRDFDEARLAC-- 142

Query: 173 ALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLP--DAVIAC 230
              +   + +   Y + +A  P            + G       LE    +P  DA+I  
Sbjct: 143 ---EARAAADGLRY-IHSANEPDL----------IAG--VGTYALEILESVPDLDAIIVP 186

Query: 231 VGGGSNAIGM-FADFINETNVGLIGVEPGGHGI 262
           +G GS   G        +  + +IGV+  G  +
Sbjct: 187 IGAGSGVCGTGIVMKTVDPAIQVIGVQAAGMPV 219


>UniRef50_C4V2P7 Threonine ammonia-lyase n=1 Tax=Selenomonas flueggei ATCC 43531
           RepID=C4V2P7_9FIRM
          Length = 416

 Score = 73.4 bits (179), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 71/339 (20%), Positives = 120/339 (35%), Gaps = 46/339 (13%)

Query: 55  RPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQ 114
           R + L      +  +    YLK E+L   GA K      +  +     +   +    AG 
Sbjct: 35  RKSPLVYSDYFSDLSGNATYLKLENLQTTGAFKLRGAYNRISMLTEEERARGVITASAGN 94

Query: 115 HGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEAL 174
           H    A ++  LG+K  I M A         V   R  GA V+   +G     DA   +L
Sbjct: 95  HAQGVAYSAQKLGVKAVICMPATTP---ILKVEATRAFGATVVLHGNG---FDDAYAHSL 148

Query: 175 RDWSGSYETAHYMLGTAAGPHPYPTI-VREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
                      Y+       HP+    V   Q  I  E    +     +  DA++  +GG
Sbjct: 149 E--LQKEHGYVYI-------HPFNDRNVIVGQGTIALEVIDAL-----KDVDAILVPIGG 194

Query: 234 GSNAIGMFADF-INETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDG 292
           G  A G+          V +IGVEP           A L  G       +  P   T   
Sbjct: 195 GGLASGIALGVKTVNPQVKVIGVEP----ENAACMKAALSCG-----HAITLPSADT--- 242

Query: 293 QIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESS 352
                  ++ G    + G            + +++++ E + A  +L     +I   E +
Sbjct: 243 -------VADGCAVRTAGTLTREFCRRYLDEIITVSEMEIMSALLSLIEKHKLI--AEGA 293

Query: 353 HALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDIL 391
             L+ A   +++   K++ + V +SG G+ DI T+  ++
Sbjct: 294 GVLSLAA--LQKLHTKDKKIAVLISG-GNIDISTISALI 329


>UniRef50_Q3ISH9 Threonine synthase 3 n=1 Tax=Natronomonas pharaonis DSM 2160
           RepID=Q3ISH9_NATPD
          Length = 388

 Score = 73.4 bits (179), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 69/342 (20%), Positives = 125/342 (36%), Gaps = 25/342 (7%)

Query: 57  TALTKCQNITAGTNT-TLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           T L     +        +++K E     G          A  A+R     +   T  G  
Sbjct: 68  TPLVAAPRLADELGVGQVFIKNEAHNPTGTITDRAAALVAAAAERADADTLALPT-TGNG 126

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
           G ++A  +A  GL  R +           N   + + G ++  V       ++A   A  
Sbjct: 127 GQSAAAYAARAGLLSRSF---VPSRANFINKAMINVHGGDMRVVEGRYDDAREAYQTARE 183

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
           +   + E A +     AGP   P    E  + +  E   Q+      +PDAV+A  G G 
Sbjct: 184 ELPAADEEAWF----PAGPFDSP-FRHEGLKPLYYELVEQLD---WTVPDAVVAPTGHGE 235

Query: 236 NAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIE 295
              G++       +VGL    P  +     +  AP+    +      +   +        
Sbjct: 236 AVAGLWKGAREFESVGLTESTPRLYA-AQPDGCAPIVD-ALDTDSDPEPWSVPDTVVGSL 293

Query: 296 ESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHAL 355
           E    + GL      P    + ++G  + V++ D + L++  T+  HEG+  ++    A 
Sbjct: 294 EIPDPAGGL------PAVEAVRASG-GEGVAVDDQDLLDSAATVAQHEGLEVSIACGAAA 346

Query: 356 AHALKMMRENP--DKEQLLVVNLSGRGDKDIFTVHDILKARG 395
           A A  +  E      + +++VN +G G+KD   V   L ++G
Sbjct: 347 AGAWDLAEEGAFDADDTVVLVN-TGTGNKDADIVRSRLMSQG 387


>UniRef50_P17324 L-serine dehydratase n=12 Tax=Fungi/Metazoa group RepID=SDHL_YEAST
          Length = 338

 Score = 73.4 bits (179), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 55/234 (23%), Positives = 92/234 (39%), Gaps = 30/234 (12%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQAL-------LAKRMGKTEIIAE 109
           T L +       TN+  Y+K E L  GG+ K+   +G  +       L++  GK  + + 
Sbjct: 9   TPLIRQVFNNGKTNSWFYVKHEILQPGGSFKSR-GIGHLIRKSNQQPLSEGSGKLAVFSS 67

Query: 110 TGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDA 169
           +G G  G+A+A A   + L C + +       +   V +++  GA+VI            
Sbjct: 68  SG-GNAGLAAATACRSMALNCSVVVPKTT---KPRMVKKIQSAGAKVIIHGDHWG----E 119

Query: 170 CNEALRDWSGSYETAHYMLGT-AAGPHPYPTIVR-EFQRMIGEETKAQILEREGRLP--D 225
            +E LR    + E+ H   G+     HP+      E    I +E   Q+ E +  LP   
Sbjct: 120 ADEYLRHKLMAQESQH---GSKTLYVHPFDNETIWEGHSTIVDEIIEQLKENDISLPRVK 176

Query: 226 AVIACVGGGSNAIGMFADFINE---TNVGLIGVEPGGHGIETGEHGAPLKHGRV 276
           A++  VGGG    G+            + ++ VE  G  +        LK G  
Sbjct: 177 ALVCSVGGGGLFSGIIKGLDRNHLAEKIPVVAVETAGCDVLNK----SLKKGSP 226


>UniRef50_A0RIY6 Cysteine synthase n=101 Tax=Bacteria RepID=A0RIY6_BACAH
          Length = 315

 Score = 73.4 bits (179), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 67/329 (20%), Positives = 118/329 (35%), Gaps = 64/329 (19%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETG----- 111
           T + +    +      L+ K E    GG+ K    LG+ L+   + +  ++ E G     
Sbjct: 22  TPIVEITRFSLPEGVRLFAKLEFYNPGGSVKDR--LGRELIEDAL-EKGLVTEGGTIIEP 78

Query: 112 -AGQHGVASALASALLGLKCRIYMGAK-DVERQSPNVFRMRLMGAEVI--PVHSGSATLK 167
            AG  G+  ALA+    L+  + +  K  +E+Q      M+ +GA V+  P   G     
Sbjct: 79  TAGNTGIGLALAALQYDLRVIVCVPEKFSIEKQE----LMKALGATVVHTPTEQGMTGAI 134

Query: 168 DACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAV 227
               E + +   SY  + +     A P  Y      F+  +G E         G + +  
Sbjct: 135 AKAKELVNEIPNSYSPSQFA--NEANPRAY------FKT-LGPEL---WSALNGEI-NIF 181

Query: 228 IACVGGGSNAIGMFADFINETNVGL--IGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAP 285
           +A  G G   +G  + ++ E N+ +  + VEP G  +  G+ G    H   GI      P
Sbjct: 182 VAGAGTGGTFMGTAS-YLKEKNIDIKTVIVEPEGSILNGGKAG---SHETEGIGLEFIPP 237

Query: 286 MMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGI 345
            ++T     +E ++IS                           D  A    K L   EG+
Sbjct: 238 FLKTSY--FDEIHTIS---------------------------DRNAFLRVKELAQKEGL 268

Query: 346 IPALESSHALAHALKMMRENPDKEQLLVV 374
           +    S  A   +L    +      ++ +
Sbjct: 269 LVGSSSGAAFHASLLEAEKAAPGTNIVTI 297


>UniRef50_A8ZXL4 Cysteine synthase n=15 Tax=cellular organisms RepID=A8ZXL4_DESOH
          Length = 771

 Score = 73.4 bits (179), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 59/329 (17%), Positives = 112/329 (34%), Gaps = 61/329 (18%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG---KTEIIAETGAG 113
           T L + + ++      ++ K E +  GG+ K    +      +  G   K +I+ E  +G
Sbjct: 12  TPLVEIRRLSPNPRVKIFAKLEYMNPGGSIKDRAAVAMIEDGEASGRLTKEKIVLEATSG 71

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
             G+  A+  A+ G +  + M              +R  GAE++       T   A  E 
Sbjct: 72  NTGIGLAMVCAIKGYRLLLAMSE---RASEERKKILRARGAEILLTPGHLGT-DGAIEEV 127

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVRE--FQRMIGEETKAQILEREGRLPDAVIACV 231
            R    + E  ++          +              +E   Q         D V+A +
Sbjct: 128 YRLARENPE-TYFC------TDQFNNEANWKAHYTGTAQEIWDQ----TEGKVDVVVATL 176

Query: 232 GGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTE 290
           G    A+G+       + ++ ++GVEP                     + G K   ++  
Sbjct: 177 GTSGTAMGLSRRLKELKPDIRIVGVEP---------------------FLGHKIQGLKN- 214

Query: 291 DGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYV-SITDDEALEAFKTLCLHEGIIPAL 349
              ++ESY            P+        R D   +I D+ A E  + L   EG++  +
Sbjct: 215 ---MKESYR-----------PEI---FEQKRLDAKPNIEDEAAYEMTRRLAREEGLLVGM 257

Query: 350 ESSHALAHALKMMRENPDKEQLLVVNLSG 378
            S  A+  A +  R       ++++  SG
Sbjct: 258 SSGAAMHVAAEEARAMEAGIIVVILPDSG 286


>UniRef50_D1B631 Threonine synthase n=2 Tax=Bacteria RepID=D1B631_THEAS
          Length = 344

 Score = 73.4 bits (179), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 68/342 (19%), Positives = 111/342 (32%), Gaps = 59/342 (17%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEII-AETGAGQH 115
           T L   + +       L+ K E     G+ K   ++     A   G   +I A TG    
Sbjct: 27  TPLVPLRALGEELGVDLWGKFEGANPTGSFKDRGMVLAVSKAMEEGARGVICASTGNTSA 86

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
             A+  A    GL C + + + +V +    V +  + GA V  V           + AL 
Sbjct: 87  SAAAYAACG--GLSCTVLLPSGNVAKGK--VAQALIYGATVAAVRGN-------FDRALE 135

Query: 176 DWSGSYETAHYMLGTAAGPHPY-PTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGG 234
                 E   Y +  +  P      +   F      E   Q+    G  PD +   VG  
Sbjct: 136 LARAMAERRGYRIVNSVNPFRLRGQMSGAF------EICDQL----GDAPDWLAIPVGNA 185

Query: 235 SNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQI 294
            N    +A F+           P   G +       +                    GQ 
Sbjct: 186 GNVTAYWAGFVAYMRRRRSSRVPVMMGFQAQGACPMVT-------------------GQF 226

Query: 295 EE-SYSISAGLDFPSVGPQH-------AYLNSTGRADYVSITDDEALEAFKTLCLHEGII 346
            +   +++  +    +G          A + S G   + ++ D E L A   L    G+ 
Sbjct: 227 TDHPETVATAIR---IGRPVNARRARWAVMMSGG--AFEAVEDREILRAQMDLARC-GLF 280

Query: 347 PALESSHALAHALKMMREN--PDKEQLLVVNLSGRGDKDIFT 386
               S   LA   K+ RE   P   ++++V L+G G KD+ T
Sbjct: 281 AEPASCTPLAGLRKLAREGRLPRGIRVVMV-LTGNGLKDVET 321


>UniRef50_A8ABB1 L-threonine synthase n=45 Tax=cellular organisms RepID=A8ABB1_IGNH4
          Length = 408

 Score = 73.4 bits (179), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 73/386 (18%), Positives = 137/386 (35%), Gaps = 57/386 (14%)

Query: 18  PQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRP-------TALTKCQNITAGTN 70
           P+ L P        F    +       F +LL   +G P       T L + + +     
Sbjct: 36  PEELPPF-----SEFTKRSRMKGIWR-FAELLPVKSGSPVTMGEGNTPLIRLEKLEKVIG 89

Query: 71  TT-LYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLK 129
              LY K E     G+ K   +     +AK +    ++A +  G    ++A  SA  GLK
Sbjct: 90  VRRLYAKFEGANPTGSFKDRGMSLAVTVAKEVKARAVVAAS-TGNTAASAAAYSARAGLK 148

Query: 130 CRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLG 189
             + + +  V           L GA V+ +        DA  EA+++ +   E   Y L 
Sbjct: 149 TFLILPSGKVALGKLAQSL--LHGAVVVELEGNF----DAALEAVKELAKMPE--FYPLN 200

Query: 190 TAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETN 249
           +      +     E Q+ +  E   +I   +  +       VG   N   ++  F     
Sbjct: 201 S------FNPWRLEGQKTLAFELFEEIGVPDVVV-----VPVGNAGNISAIWKGFKELKE 249

Query: 250 -------VGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISA 302
                    ++GV+  G         A           G+ AP+       +  +  I  
Sbjct: 250 FGYSEALPKMVGVQAEGASPIASAFKA-----------GLNAPLFTDSPETVATAIRIGK 298

Query: 303 GLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMM 362
            +++  +    A   S G   +  ++D E + A + L   EG+      + +LA  +++ 
Sbjct: 299 PVNW--MKAWKAVTESGG--TFEVVSDSEIIRAQRLLAREEGVAAEPAGAASLAGVVRLA 354

Query: 363 RENP-DKEQLLVVNLSGRGDKDIFTV 387
            E   + ++++ V ++G G KD  +V
Sbjct: 355 SEGYFNGDEVVTVVVTGHGLKDPDSV 380


>UniRef50_C7N157 Cysteine synthase n=3 Tax=Bacteria RepID=C7N157_SLAHD
          Length = 321

 Score = 73.0 bits (178), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 36/121 (29%), Positives = 53/121 (43%), Gaps = 7/121 (5%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK---TEIIAETGAG 113
           T L + Q I+      + +K E +  GG+ KT       L A++ G+     I+ E  +G
Sbjct: 24  TPLIELQRISEPNAARILVKYEGVNIGGSVKTRTAYQMILEAQKRGEITSDSIVVEPTSG 83

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
             G+  AL  A+LGL+ RI M     E        +R  GAEVI V      +  A  E 
Sbjct: 84  NQGIGLALVCAVLGLQARIIMPDSVSEE---RRKLVRHYGAEVI-VVHDEGDIGKAIQEC 139

Query: 174 L 174
           +
Sbjct: 140 I 140


>UniRef50_A8MDC1 Threonine dehydratase n=9 Tax=cellular organisms RepID=A8MDC1_CALMQ
          Length = 418

 Score = 73.0 bits (178), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 64/292 (21%), Positives = 98/292 (33%), Gaps = 42/292 (14%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T L +   +++ TN  +YLK E L   G+ K                  ++  + AG H 
Sbjct: 37  TPLYRSDTLSSLTNADVYLKLEALQKTGSFKVRGAYNAVTHYINDDVKHVVTAS-AGNHA 95

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVI-PVHSGSATLKDACNEALR 175
              A  + + GLK  I M       +  N    R  GAEVI    S     K A  E  +
Sbjct: 96  QGVAYVAKIYGLKSTIVMPKYTPWIKISNT---RKYGAEVILEGQSYYEAEKYAI-ELTK 151

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
           +       A+          P+   V   Q  IG E    +        D VI  VGGG 
Sbjct: 152 ELKAKMIHAY--------DDPF---VIAGQGTIGWEIIEDLKNI-----DYVIVPVGGGG 195

Query: 236 NAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQI 294
              G+ +       N  +IGV+            A L              + Q +   +
Sbjct: 196 LISGIASVIKTISPNTRVIGVQSEITP------SAYLS-------------LKQGKIITV 236

Query: 295 EESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGII 346
           E + +I+ G+    +G     +      D V ++D E + A   L     +I
Sbjct: 237 ENTDTIADGIAVKKIGDLTFDIMRNTLDDVVLVSDQEIVNAILILAESAKVI 288


>UniRef50_Q2SDR6 Threonine dehydratase n=1 Tax=Hahella chejuensis KCTC 2396
           RepID=Q2SDR6_HAHCH
          Length = 330

 Score = 73.0 bits (178), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 47/228 (20%), Positives = 79/228 (34%), Gaps = 27/228 (11%)

Query: 33  VSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVL 92
                  +       + +N   +PT L + ++++      +Y+K E+     + K    +
Sbjct: 3   DQVVDIRDIFKARQTVSRN--LKPTQLLRYESLSRLIGADIYIKHENHNPTASQKIRGAV 60

Query: 93  GQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLM 152
             A   +R G T I+     G  G+A A A+ L  +   + +  K           ++  
Sbjct: 61  NLAWELRRNGVTRIVTA-ANGASGLALACAARLFNMSALVVVPEKSP---LSLTQPIQDQ 116

Query: 153 GAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEET 212
           GAEV               E+LR      E          G + +     E Q + G   
Sbjct: 117 GAEVRAS-------GIDFPESLRIARRMEEN---------GDYYFVHPANEMQFIHG--C 158

Query: 213 KAQILEREGRLP--DAVIACVG-GGSNAIGMFADFINETNVGLIGVEP 257
               LE    LP  D  I  VG GG  A  + A  +    + +IGV+ 
Sbjct: 159 ATAALEMIEELPEADVAIGSVGMGGCIASTLAASSVLNPKLKVIGVQA 206


>UniRef50_Q28WC6 L-threonine ammonia-lyase n=35 Tax=Alphaproteobacteria
           RepID=Q28WC6_JANSC
          Length = 425

 Score = 73.0 bits (178), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 40/177 (22%), Positives = 66/177 (37%), Gaps = 18/177 (10%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEII--AETGAGQ 114
           T L K   ++      ++LKREDL    ++K       A+   R  + E++      AG 
Sbjct: 32  TPLLKNAYLSERFGADIWLKREDLSPVRSYKLRGAF-NAMRKVRAERPELVDFVCASAGN 90

Query: 115 HGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEAL 174
           H    A   A  G++ R+YM     +++       R  G + + +        D    A 
Sbjct: 91  HAQGVAYVCAHFGVRGRVYMPVTTPDQKILKT---RTFGGDAVEIVL-EGDFFDETQAAA 146

Query: 175 RDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACV 231
           + +      AH+       P   P  V E Q  +  E   Q+    GR PD ++  V
Sbjct: 147 KAYCAEVG-AHF-----LSPFDDPD-VIEGQASVAVEMLEQL----GRAPDHLVLPV 192


>UniRef50_C4XII8 Cysteine synthase B n=3 Tax=Desulfovibrio RepID=C4XII8_DESMR
          Length = 773

 Score = 73.0 bits (178), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 70/327 (21%), Positives = 113/327 (34%), Gaps = 57/327 (17%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK---TEIIAETGAG 113
           T L + + +      T+  K E    GG+ K    L     A+R G+      + E  +G
Sbjct: 13  TPLVRMRRVCPNPRVTICAKIESRNPGGSIKDRVALAMIEAAERSGELTSGRTVIEATSG 72

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
             G+  A+  A+ G   ++ M A   E        MR  GAE++       T   A  EA
Sbjct: 73  NTGIGLAMVCAVKGYPLKLLMPASASEE---RKRIMRAYGAEIVLTPGNRGT-DGAIEEA 128

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
            R      E   Y+L         P  +         E    I E  G     V+A +G 
Sbjct: 129 YR--LAREEPDRYVL---MDQFNNPASIEAHYAATAVE----IFESTGGAVTHVVAALGT 179

Query: 234 GSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGI-YFGMKAPMMQTED 291
              A+G+          + +  VEP                 R G    G+K        
Sbjct: 180 SGTAMGLVKKLKELNPAITVAAVEP-----------------RPGHKIQGLK-------- 214

Query: 292 GQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALES 351
             ++ESY        P +  +HA          V + D++A    + L   EGI+  +  
Sbjct: 215 -NMQESYP-------PGIFNKHA------LDAIVPVEDEDAFAMARRLARDEGILAGMSG 260

Query: 352 SHALAHALKMMRENPDKEQLLVVNLSG 378
             A+A A ++  E  +   ++++  SG
Sbjct: 261 GAAMAAAARLAGELAEGLIVVILADSG 287


>UniRef50_D1IAP7 Whole genome shotgun sequence of line PN40024,
           scaffold_7.assembly12x (Fragment) n=3 Tax=Magnoliophyta
           RepID=D1IAP7_VITVI
          Length = 606

 Score = 73.0 bits (178), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 52/205 (25%), Positives = 76/205 (37%), Gaps = 25/205 (12%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAK--RMGKTEIIAETGAGQ 114
           + L     ++      ++LKREDL    + K        ++AK  +      +  + AG 
Sbjct: 124 SPLQLAPKLSERLGAQIWLKREDLQPVFSFKLRGAYN--MMAKIPKEQLERGVICSSAGN 181

Query: 115 HGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEAL 174
           H    ALA+  LG    I M     E +  +V     +GA V+ V        D+ +EA 
Sbjct: 182 HAQGVALAAKRLGCNAVIAMPVTTPEIKWKSV---ERLGATVVLV-------GDSYDEAQ 231

Query: 175 RDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGG 234
                  E       T   P  +P  V   Q  IG E   Q+        DA+   VGG 
Sbjct: 232 AYAKQRGEEE---CRTFIPPFDHPD-VIMGQGTIGMEIVRQMQGPL----DAIFVPVGG- 282

Query: 235 SNAIGMFADFINE--TNVGLIGVEP 257
              I   A ++      V +IGVEP
Sbjct: 283 GGLIAGIAAYVKRVSPEVKIIGVEP 307


>UniRef50_C5EHA5 L-threonine synthase n=1 Tax=Clostridiales bacterium 1_7_47FAA
           RepID=C5EHA5_9FIRM
          Length = 402

 Score = 72.6 bits (177), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 83/340 (24%), Positives = 130/340 (38%), Gaps = 50/340 (14%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE---IIAETGAG 113
           TALTK + +       LY+K E       HK    L   L+ K M       I A TG  
Sbjct: 65  TALTKLERLGEELEIDLYMKDETRNPTWGHKDR--LNAVLINKAMELKAPGVIYASTG-- 120

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGS---ATLKDAC 170
            +G + A  +A  GL C I M    V  ++   F M++ GA +I V + +     LK   
Sbjct: 121 NNGASGAAFAAKAGLPCII-MTVTGVN-KTLETF-MQIYGASLIGVKTTADRWKVLKHMV 177

Query: 171 NEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIAC 230
           +E     +G Y   +Y++    G +P+     +  ++I  E   Q+      LPD ++  
Sbjct: 178 DE-----NGWYPATNYVV-PIVGSNPW---AIDGYKVISYELYKQM----DVLPDKIVVP 224

Query: 231 VGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYF-----GMKAP 285
           +  G    G+   F     +G I   P    +E     A   +G + I       G  A 
Sbjct: 225 ICYGDALFGIMKGFSELKEMGFIDKIPQMVSVEDYGPVAKAYNGNLDIIEPVEGWGSVAS 284

Query: 286 MMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGI 345
            M T  G             + S+   HA   S G A  +     E  EA + L   EG+
Sbjct: 285 SMSTIWGT------------YHSL---HALKKSNGLAVSLEGN-GEINEAQRELAQKEGV 328

Query: 346 IPALESSHALAHALKMMRENPDK---EQLLVVNLSGRGDK 382
                S+  LA   +++ E   K   + ++++  SG  D 
Sbjct: 329 YCESASASTLAGLRRLISEGKIKKGEKVVILITASGVKDT 368


>UniRef50_Q54HH2 Probable serine racemase n=1 Tax=Dictyostelium discoideum
           RepID=SRR_DICDI
          Length = 324

 Score = 72.3 bits (176), Expect = 3e-11,   Method: Composition-based stats.
 Identities = 71/356 (19%), Positives = 120/356 (33%), Gaps = 52/356 (14%)

Query: 43  AQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQAL-LAKRM 101
            + +  ++ Y  + T +     I       LY K E+L   G+ K          L +  
Sbjct: 13  KEAHKRIEKYIHK-TPVLTNSTINELAGKELYFKCENLQKTGSFKMRGACNAIFSLDEEE 71

Query: 102 GKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS 161
               ++  + +G HG A + AS +  +KC + +       +   +      GA V     
Sbjct: 72  LSKGVVTHS-SGNHGQALSYASKVRCVKCYVVVPEDAPSVKLNAICG---YGATV----- 122

Query: 162 GSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTI-VREFQRMIGEETKAQILERE 220
              T   A  EA    +      H    +    HP+  + V   Q     E   Q+    
Sbjct: 123 ---TKCKATLEARESNTKQLIEQH----SCKLIHPFDNLQVIAGQGTASLELMEQV---- 171

Query: 221 GRLPDAVIACVGGGSNAIGM-FADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIY 279
               DA+I  VGGG    G          N+ +   EP G      +    L  G +   
Sbjct: 172 -ENLDAIITPVGGGGLLSGTCITAKSLNPNIKVFAAEPLG----ADDTYRSLLSGEI--- 223

Query: 280 FGMKAPMMQTEDGQIEESYSISAGLDFPSVG----PQHAYLNSTGRADYVSITDDEALEA 335
                     +     +  +I+ GL   +VG    P               +T+DE   A
Sbjct: 224 ----------QKHTPGKPNTIADGL-LTTVGSLTFPIIKENCDGVIL----VTEDEIKYA 268

Query: 336 FKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDIL 391
            K +     II    S+  LA  LK   ++    + + + +SG G+ D+ ++  IL
Sbjct: 269 MKLVWERMKIIIEPSSATTLAAILKQEFKDKKDIKKVGIIISG-GNVDLSSISKIL 323


>UniRef50_A0E1N6 Cysteine synthase n=2 Tax=Oligohymenophorea RepID=A0E1N6_PARTE
          Length = 351

 Score = 72.3 bits (176), Expect = 3e-11,   Method: Composition-based stats.
 Identities = 66/332 (19%), Positives = 123/332 (37%), Gaps = 42/332 (12%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG----KTEIIAETGA 112
           T L   ++++  T   +Y K E +  G + K    L       + G    K   I E  +
Sbjct: 32  TPLIYLKSLSEQTGREIYAKCEFMNPGSSMKDRTALALIQYGIQHGHLGVKNNTIYEGTS 91

Query: 113 GQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNE 172
           G  GV+  L    LG KC++Y+   D+ ++  N+   +  GA +  V     ++ D+   
Sbjct: 92  GSTGVSLTLIGNSLGCKCKLYL-QNDLAQEKYNIL--QTCGAIIEKVP--PVSIVDS--- 143

Query: 173 ALRDWSGSYETAHYMLGTAAGP--HPYPTIVREFQRMIGEETKAQILEREGRLPDAVIAC 230
               +    E   Y+ G       H        FQ   G+E   Q       L D  +  
Sbjct: 144 --EHFCKKAEKQAYIEGGYYADQFHNLANQQAHFQT--GKEIYKQ----TNGLIDCFVMS 195

Query: 231 VGGGSNAIGMFADFI--NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQ 288
            G G +  G+ + ++     N+ +I  +P G  ++T  +       +      +K P   
Sbjct: 196 SGTGGSIAGI-SQYLKGKNKNIKVILADPPGSSLKTHVNSGVCYTYQEAEGHRLKNPF-- 252

Query: 289 TEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADY-VSITDDEALEAFKTLCLHEGIIP 347
                  ++     GL+      +        + DY  +I D E+++  + L   EG+  
Sbjct: 253 -------DTVIEGCGLN------RLTKNYLQAKIDYGFTIQDKESIQMAEFLIEKEGLFV 299

Query: 348 ALESSHALAHALKMMRENPD-KEQLLVVNLSG 378
              S+      LK + + P+ K  + ++  SG
Sbjct: 300 GASSAMNCVAVLKAVEKYPECKVFVTILCDSG 331


>UniRef50_A5IQ12 Cysteine synthase n=51 Tax=Staphylococcus aureus RepID=A5IQ12_STAA9
          Length = 318

 Score = 72.3 bits (176), Expect = 3e-11,   Method: Composition-based stats.
 Identities = 67/324 (20%), Positives = 116/324 (35%), Gaps = 59/324 (18%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEI-----IAETG 111
           T L   ++ +      +Y K E    GG+ K    LG+ L+ K + +  +     I E  
Sbjct: 27  TPLVLLEHYSDD-KVKIYAKLEQWNPGGSVKDR--LGKYLVEKAIQEGRVRAGQTIVEAT 83

Query: 112 AGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACN 171
           AG  G+  A+A+    LKC+I+            +  M  +GA+V    S S  +  A  
Sbjct: 84  AGNTGIGLAIAANRHHLKCKIF---APYGFSEEKINIMIALGADV-SRTSQSEGMHGAQL 139

Query: 172 EALRDWSGSYETAHY-MLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIAC 230
            A R ++  Y   +     +   P  Y      F   +G E  + + +      D  +A 
Sbjct: 140 AA-RSYAEKYGAVYMNQFESEHNPDTY------FHT-LGPELTSALQQI-----DYFVAG 186

Query: 231 VGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTE 290
           +G G    G    ++ + +V    VEP G  +  G   A                     
Sbjct: 187 IGSGGTFTGTAR-YLKQHHVQCYAVEPEGSVLNGGPAHA------------------HDT 227

Query: 291 DGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALE 350
           +G   E + I              +L         +I D +A    K+L ++EG++    
Sbjct: 228 EGIGSEKWPI--------------FLERRLVDGIFTIKDQDAFRNVKSLAINEGLLVGSS 273

Query: 351 SSHALAHALKMMRENPDKEQLLVV 374
           S  AL  AL +  +  +   ++V 
Sbjct: 274 SGAALQGALNLKAQLSEGTIVVVF 297


>UniRef50_Q2CF35 Threonine synthase n=1 Tax=Oceanicola granulosus HTCC2516
           RepID=Q2CF35_9RHOB
          Length = 420

 Score = 72.3 bits (176), Expect = 3e-11,   Method: Composition-based stats.
 Identities = 70/331 (21%), Positives = 117/331 (35%), Gaps = 35/331 (10%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T L +   +    +  ++ K E     G+ K          AK +G   I+  +  G + 
Sbjct: 77  TPLLRLSRL--FPDRPVWAKLEFTNPTGSFKDRGSAVAVSAAKALGAEGIVCAS-TGNNA 133

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGA---EVIPVHSGSATLKDACNEA 173
            + +  +A  GL C + +G      +   V + +  GA   EV    S +  + +  N A
Sbjct: 134 ASVSAYAARAGLPCIVTLGKGTPVAK---VLQAKAHGAITVEVAGDFSDAYRMAEEINRA 190

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
              W+ +  + +        P+            I  E     +E  G  P+AV+  VG 
Sbjct: 191 DPAWA-NLTSTY------LNPYTTVAH-----STILYEV----VEEIGA-PEAVVVPVGA 233

Query: 234 GSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQ 293
           G    G+          G +   P   G+  G   AP+         G +      E   
Sbjct: 234 GPMLDGIVTGARRMQAAGRLETIPRPIGV-QGAGCAPIAR---AFAEGAEEVAAWGEVSG 289

Query: 294 IEESYSISAGLD-FPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESS 352
           I    SI+  L  +P  G +   L        V+++DDE  +A + L   EGI  A E +
Sbjct: 290 I--PGSINDALRGYPEDGTRTLRLIRETAGAAVAVSDDEIRDAMRELGAREGI--AAEPA 345

Query: 353 HALAHALKMMRENPDKEQLLVVNLSGRGDKD 383
            A   A        +    +V+ +SG   KD
Sbjct: 346 SAATLAALRRAPLGELSGPVVLVISGHALKD 376


>UniRef50_Q17VY7 Cysteine synthase n=29 Tax=Bacteria RepID=Q17VY7_HELAH
          Length = 304

 Score = 72.3 bits (176), Expect = 3e-11,   Method: Composition-based stats.
 Identities = 81/327 (24%), Positives = 131/327 (40%), Gaps = 59/327 (18%)

Query: 57  TALTK-CQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALL--AKRMGK---TEIIAET 110
           T + K  +N     N+ +Y K E L  GG+ K    LGQ L+  A R  K   T  I E 
Sbjct: 13  TPIFKFTRNYPIPKNSVIYAKLEHLNPGGSVKDR--LGQYLIKEAFRTHKITPTTTIIEP 70

Query: 111 GAGQHGVASALASALLGLKCRIYMGAK-DVERQSPNVFRMRLMGAEVIPVHSGSATLKDA 169
            AG  G+A AL +    LK    +  K  VE+Q      M+ +GA VI   + S  +  A
Sbjct: 71  TAGNTGIALALVALKHHLKTIFVVPEKFSVEKQQ----IMKALGATVINTPT-SEGISGA 125

Query: 170 CNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIA 229
             ++ ++ + S   ++  L      +P       +  +  E     I ++ G    + +A
Sbjct: 126 IKKS-KELAKSIPDSYLPLQFENFDNPN----AYYHTLAPE-----IFQKLGTGLTSFVA 175

Query: 230 CVGGGSNAIGMFADFINE--TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMM 287
            +G G    G  A ++ E    + LIGVEP G  +  GE G     G +G+ F       
Sbjct: 176 GIGSGGTFAGTAA-YLKERIPTIRLIGVEPEGSILNGGEPGPHEIEG-IGVEF------- 226

Query: 288 QTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIP 347
                                + P  A L+  G   + +I+D+E     + L    G++ 
Sbjct: 227 ---------------------IPPFFANLDIDG---FETISDEEGFHYTRELAKKNGLLV 262

Query: 348 ALESSHALAHALKMMRENPDKEQLLVV 374
              S    A AL+ ++  P+  Q+L +
Sbjct: 263 GSSSGAVFAAALREVQRLPNGSQVLTI 289


>UniRef50_A7INC1 Threonine dehydratase n=6 Tax=Alphaproteobacteria
           RepID=A7INC1_XANP2
          Length = 425

 Score = 71.9 bits (175), Expect = 4e-11,   Method: Composition-based stats.
 Identities = 58/239 (24%), Positives = 86/239 (35%), Gaps = 32/239 (13%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQ-ALLAKRMGKTEIIAETGAGQH 115
           T       ++A T   +Y+K E+L    + K    L + A L     +  ++A + AG H
Sbjct: 40  TPTLHAPRLSALTGADVYVKYENLQVTASFKERGALVKLARLTPEEARRGVVAMS-AGNH 98

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
             A A     L +   I M     + +   V      GAEV+       T+ DA  EA R
Sbjct: 99  AQAVAYHGTRLKISTLIVMPETTPQVK---VAATEAFGAEVVLF---GDTVADAFEEATR 152

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTI-VREFQRMIGEETKAQILEREGRLPDAVIACVGGG 234
                 +   ++       HPY  + V   Q  +  E     +  +G   DAV+  +GGG
Sbjct: 153 --ISKAQGRIFV-------HPYDDVDVIAGQGSLALE-----MMEDGPAFDAVVVPIGGG 198

Query: 235 SNAIGMFADFINE-TNVGLIGVE----PGGHGIETGEH----GAPLKHGRVGIYFGMKA 284
               GM   F        ++GVE    P      TGE     G  L  G      G+  
Sbjct: 199 GLIAGMALAFAGRSPATQVVGVETQLYPAMWSAMTGEARPCGGPTLAEGIAVRDVGVIT 257


>UniRef50_Q07RL7 L-threonine ammonia-lyase n=40 Tax=Bacteria RepID=Q07RL7_RHOP5
          Length = 345

 Score = 71.9 bits (175), Expect = 4e-11,   Method: Composition-based stats.
 Identities = 53/231 (22%), Positives = 85/231 (36%), Gaps = 21/231 (9%)

Query: 46  NDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE 105
             +LK YA R T L     + A T   ++LK E L   G+ K      +        +  
Sbjct: 19  AQVLKPYAVR-TPLLSSPALDALTGARVFLKPEMLQRTGSFKFRGAFNKLSSIPAEARAG 77

Query: 106 IIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSAT 165
            +    +G H    A A+ +LG++  I M A     +       +  GAEV+        
Sbjct: 78  GVVAFSSGNHAQGVAAAAQILGMRATIVMPADAPASKRERT---KSYGAEVVLYDRLRED 134

Query: 166 LKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPD 225
            ++A    + + +G+         T   P+  P  V   Q  +G E   Q L  +G  PD
Sbjct: 135 -REAIARRIAEQTGA---------TLVPPYDDPK-VIAGQGTVGREI-VQDLAAQGLSPD 182

Query: 226 AVIACVGGGSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGR 275
            VIA   GG    G+     +      ++  EP        +H   L+ G+
Sbjct: 183 LVIAPASGGGLLAGIAVAVRSHCPQATILCAEPEAF----DDHARSLRAGQ 229


>UniRef50_A0LG82 L-threonine ammonia-lyase n=2 Tax=cellular organisms
           RepID=A0LG82_SYNFM
          Length = 416

 Score = 71.9 bits (175), Expect = 4e-11,   Method: Composition-based stats.
 Identities = 78/381 (20%), Positives = 128/381 (33%), Gaps = 93/381 (24%)

Query: 39  PEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLA 98
           P    +  + LK    R T L      +      +YLK E+L   G+ K      + +  
Sbjct: 12  PSVIRKAAEALKGRVLR-TPLVYSSTFSRLCGAKVYLKLENLQETGSFKLRGATWKIMSN 70

Query: 99  -KRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGA-KDVERQSPNVFRMRLMGAEV 156
             R+G   ++A + AG H    ALA++   L   + M     + +Q       R  GAEV
Sbjct: 71  LHRIGPDGVVAAS-AGNHAQGVALAASRAKLPSTVIMPEWASISKQEAT----RNYGAEV 125

Query: 157 IPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTI-VREFQRMIGEETKAQ 215
           I       +L DA  +A +      E    ++      HP+    V   Q  IG E   +
Sbjct: 126 II---EGQSLSDAIRKAGQL----VERGKTLI------HPFDDPDVMAGQGTIGLEILEE 172

Query: 216 ILEREGRLPDAV--------------IACVGGGSNAIGMFADFINETNVGLIGVEPGGHG 261
           + E     PD V              +AC                     ++GV+     
Sbjct: 173 LPE-----PDLVVVPVGGGGLIGGIAVACRS-------------VRPETRIVGVQAQACP 214

Query: 262 IETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQ-HAYLNSTG 320
                    L+ GRV      K               S++ G+    VG    A +    
Sbjct: 215 ----SACRSLESGRVVSVEAQK---------------SLADGITVKQVGALPFAVMKEM- 254

Query: 321 RADYVSITDDEALEAF--------KTLCLHEGIIPALESSHALAHALKMMRENPDKEQLL 372
             D + + +++A+ A         K L    G +P       LA  +    E P    ++
Sbjct: 255 -VDEIVLVEEDAIAAAVLMLLERKKLLAEGAGAVP-------LAALMSCSFEVPKGGTVV 306

Query: 373 VVNLSGRGDKDIFTVHDILKA 393
           +V +SG G+ D   +  +L+ 
Sbjct: 307 LV-ISG-GNMDSPLLGRVLRK 325


>UniRef50_C1AEM2 Cystathionine beta-synthase n=1 Tax=Gemmatimonas aurantiaca T-27
           RepID=C1AEM2_GEMAT
          Length = 479

 Score = 71.9 bits (175), Expect = 4e-11,   Method: Composition-based stats.
 Identities = 68/333 (20%), Positives = 106/333 (31%), Gaps = 48/333 (14%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE---IIAETGAG 113
           T L     +  G  T L  K +    GG+ K    L      +  G  +    I E  +G
Sbjct: 34  TPLIHLARVAKGIRTPLLGKADFFNPGGSVKDRIGLPMIEAHEAAGTLKPGGTIVEATSG 93

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
             GV  A+A+AL G +C   M  K  + +   V  ++  GAEVI   +         +  
Sbjct: 94  NTGVGLAIAAALKGYRCIFTMPDKMSQEK---VRLLKAFGAEVIITPTAVP-----PDHP 145

Query: 174 LRDWSGSYETAHYMLGTAA-GPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVG 232
                 +        G    G    P          G E   Q   R        +A  G
Sbjct: 146 QNYVQMAKRIVKETPGAVLAGQFENPANPAAHVATTGPEIWEQTQGRI----THFVASAG 201

Query: 233 GGSNAIGMF-ADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTED 291
            G    G+         N+ +I  +P G  +      A L   +              E 
Sbjct: 202 TGGTITGVARYLKSKNPNIKIIAADPMGSVL------AELWRSK-------------GEG 242

Query: 292 GQIEESYSISAGLDFPSVG----PQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIP 347
                 Y +        VG    P+   L+ +   +++S++D +A    + L   EGI  
Sbjct: 243 HPTGAPYKVE------GVGQDCVPE--TLDMSVIDEFISVSDKDAFSMARRLTREEGIFV 294

Query: 348 ALESSHALAHALKMMRENPDKEQLLVVNLSGRG 380
              +      AL + R   D E ++V  L   G
Sbjct: 295 GGSAGLIAHAALNVARRLDDPEAMVVTFLCDTG 327


>UniRef50_Q9X7F1 Probable threonine dehydratase biosynthetic n=24
           Tax=Actinomycetales RepID=THD1_MYCLE
          Length = 427

 Score = 71.9 bits (175), Expect = 4e-11,   Method: Composition-based stats.
 Identities = 69/349 (19%), Positives = 117/349 (33%), Gaps = 57/349 (16%)

Query: 56  PTALTKCQNITAGTNTTLYLKREDLLHGGAHKTN---QVLGQALLAKRMGKTEIIAETGA 112
           PT L     ++A T   +YLKREDL    ++K      +L Q  L        ++  + A
Sbjct: 32  PTPLQLSDRLSAITGAAVYLKREDLQTVRSYKLRGAYNLLVQ--LTDEEIAAGVVCSS-A 88

Query: 113 GQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNE 172
           G H    A A   LG+  R+Y+ AK  +++      +R  G   I +  G +T     + 
Sbjct: 89  GNHAQGVAYACRSLGVHGRVYVPAKTPKQKWDR---IRYHGGAFIELIVGRSTY----DL 141

Query: 173 ALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPD------A 226
           A        E      G    P      V   Q  I  E   Q+       PD       
Sbjct: 142 AAAAAVDDIERT----GATLVPPYDDVRVIAGQGTIAVELLEQLNTE----PDLVVVPVG 193

Query: 227 VIACVGGGSNAIGMFADFINETNVG--LIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKA 284
              C+ G          ++ E      ++GVEP G                         
Sbjct: 194 GGGCIAG-------MTTYLAERTANTAVLGVEPAGAAAMMAALA-------------AGE 233

Query: 285 PMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEG 344
           P+      Q  +     A ++     P  A   +       ++ +     A   L  +EG
Sbjct: 234 PVTLDYVDQFVD----GAAVNRVGTLPYAALTAAGDMVSITTVDEGAVCTAMLDLYQNEG 289

Query: 345 IIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
           II     + ++A    ++  + +    +V  +SG G+ D+    ++L+ 
Sbjct: 290 IIAEPAGALSVAG---LLETDIEPGSTVVCLISG-GNNDVLRYGEVLER 334


>UniRef50_A4FDD4 1-aminocyclopropane-1-carboxylate deaminase n=15 Tax=Bacteria
           RepID=A4FDD4_SACEN
          Length = 336

 Score = 71.9 bits (175), Expect = 4e-11,   Method: Composition-based stats.
 Identities = 69/351 (19%), Positives = 123/351 (35%), Gaps = 69/351 (19%)

Query: 56  PTALTKCQNITAGTN-TTLYLKREDLLHGGAHKTNQVLGQALL---AKRMGKTEIIAETG 111
           P+ + + + +TA      ++ KRED   G A+  N+      L   A   G   +++  G
Sbjct: 15  PSPVHRLERLTAHLGGAEIWAKREDCNSGIAYGGNKTRKLEYLVADALSQGCDTLVSIGG 74

Query: 112 A-GQHGVASALASALLGLKCRIYMGA-----KDVERQSPNVFRMRLMGAEVIPVHSGSA- 164
               H    A  +A  GLKC +   +       V  +  N+   RL GA+V  V +G   
Sbjct: 75  VQSNHTRQVAAVAARAGLKCVLVQESWVDWPDAVYDKVGNILVSRLAGADVRLVKAGFGI 134

Query: 165 TLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGE-------ETKAQIL 217
             K++  +A+ +   +             P+P P    +  R+ G        E   Q  
Sbjct: 135 GFKESWEQAIAEIEAAGGK----------PYPIPAGASDH-RLGGLGFANWAFEVAEQER 183

Query: 218 EREGRLPDAVIACVGGGSNAIGMFADF--INETNVGLIGVEPGGHGIETGEHGAPLKHGR 275
           +  G   D V+ C   GS   GM A F  +      ++G++      ET    A +    
Sbjct: 184 QL-GVFFDTVVVCSVTGSTQAGMIAGFAALGGRPRRILGIDASARPKETWNQIARIARNT 242

Query: 276 VGIYFGMKAP----MMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDE 331
             +    + P    ++  E               +               A    I D+ 
Sbjct: 243 TSLLELGREPADDEILLDE--------------RYH--------------AGTYGIPDES 274

Query: 332 ALEAFKTLCLHEGII--PALESSHALAHALKMMR--ENPDKEQLLVVNLSG 378
            L+A +     EG++  P  E   ++A  + ++   E  +   +L  +L G
Sbjct: 275 TLDAMRLAARTEGMVTDPVYE-GKSMAGLIDLVTRGEIAEDTTVLYAHLGG 324


>UniRef50_B6YXV5 Threonine synthase n=2 Tax=Thermococcus RepID=B6YXV5_THEON
          Length = 377

 Score = 71.5 bits (174), Expect = 5e-11,   Method: Composition-based stats.
 Identities = 74/361 (20%), Positives = 122/361 (33%), Gaps = 57/361 (15%)

Query: 39  PEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLA 98
            +F     +L  +     T L +   +       LYLK E      + K          A
Sbjct: 43  YDFWPVEPNLELSLGEGDTPLIRS-RLGKELGVKLYLKNETANPTWSFKDRGTFLAMSYA 101

Query: 99  KRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIP 158
            ++G   +      G    + A  +A  GLK +I +     + +   V    + GA+VI 
Sbjct: 102 VKVGYKAVGT-VSTGNMAASVAAYAARAGLKAKILVSGSASDEKLKAVS---IYGADVIR 157

Query: 159 VHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPH----PYPTIVREFQRMIGEETKA 214
           V            +  R +  S E     LG   G +      P  V  ++  I  E   
Sbjct: 158 V----------MGDYGRLYFESLE-----LGEELGIYFMNSDNPFRVEGYKS-IAFEIAE 201

Query: 215 QILEREGRLPDAVIACVGGGSNAIGMFADFIN-------ETNVGLIGVEPGGHGIETGEH 267
           ++       PD V+     G    G+   F+        +    LI V+  G        
Sbjct: 202 ELT------PDYVLIPTSSGGLFRGIAKGFLELFASGLIDKIPTLIAVQAEGCS----PI 251

Query: 268 GAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSI 327
                 G+ G     + P  +T    IE  Y  S  +           L   G    V++
Sbjct: 252 CRAFSEGK-GRIERFETP--RTIAHAIENPYPPSGNV-------VLKLLRELG-GKCVTV 300

Query: 328 TDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTV 387
           +D+E LEA K L   EG      S+  +A   K+    P++ +++ + L+G G K I  +
Sbjct: 301 SDEEILEAQKRLAE-EGFFVQPSSATGIAALKKL--NIPEEAKVVSI-LTGSGLKTISQI 356

Query: 388 H 388
            
Sbjct: 357 E 357


>UniRef50_C3J6F5 Cysteine synthase n=2 Tax=Bacillaceae RepID=C3J6F5_9BACI
          Length = 331

 Score = 71.5 bits (174), Expect = 5e-11,   Method: Composition-based stats.
 Identities = 66/323 (20%), Positives = 111/323 (34%), Gaps = 54/323 (16%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK----TEIIAETGA 112
           T + K + +       +Y+K E    GG+ K          A+  GK       I E  +
Sbjct: 38  TPIVKLRRLPDPNGAEVYIKLESFNPGGSVKDRPAWEMIRRAEAEGKITPGKSTIIEPTS 97

Query: 113 GQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNE 172
           G  G+  A+  A  G +C I M           V  ++  GAEV    +    ++ A +E
Sbjct: 98  GNTGIGLAMVCAARGYRCIITMPD---NATVERVKILKAYGAEVYLTPAEKR-MQGAIDE 153

Query: 173 ALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVG 232
           A R  S   ++  ++      P                 T  +I E      DA +   G
Sbjct: 154 ANRLASEIPDS--FIPMQFENPANPDAHRHT--------TAVEIYEAFDGRLDAFVLTAG 203

Query: 233 GGSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTED 291
            G    G   +      N+ +  VEP G  +        L  G+ G              
Sbjct: 204 TGGTVTGTGEELKKRIPNLRIYVVEPYGSPV--------LSGGKPG-------------- 241

Query: 292 GQIEESYSISAGLDFPSVGP--QHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPAL 349
                 + I      P  GP      LN +   D   I D++A +  + L   EGI+   
Sbjct: 242 -----PHKI------PGTGPGFIPKILNRSIYDDIFLIKDEDAQQMARELAAKEGILVGA 290

Query: 350 ESSHALAHALKMMRENPDKEQLL 372
            ++ +  +A+K+ ++ P   ++L
Sbjct: 291 SAAASAYYAIKVAKQLPKGARVL 313


>UniRef50_C6UN42 Putative cysteine synthase A n=1 Tax=Candidatus Hodgkinia
           cicadicola Dsem RepID=C6UN42_HODCD
          Length = 315

 Score = 71.5 bits (174), Expect = 5e-11,   Method: Composition-based stats.
 Identities = 67/327 (20%), Positives = 113/327 (34%), Gaps = 56/327 (17%)

Query: 57  TALTKCQNITA--GTNTTLYLKREDLLHGGAHK--TNQVLGQALL-AKRMGKTEIIAETG 111
           T + +   + A  G    LY K E +   G+ K      L   L+  +++    +I E  
Sbjct: 18  TPVLRLSRLEAKHGLKAQLYAKLESVNPLGSVKDRIANALIDELIKTRQLKANGVIIEAT 77

Query: 112 AGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACN 171
           +G  GVA A A+A  GL C + +        +     + L+GA ++    G   +KDA  
Sbjct: 78  SGNTGVALASAAASRGLSCIVVVPE---GASAERRSMLDLLGARLVFAGRG---IKDAIK 131

Query: 172 EALRDWSGSYETAHYMLGTAA-GPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIAC 230
            A +      E      G+A       P   +  +R   +E   Q+        D ++A 
Sbjct: 132 RA-KVLQARIE------GSALANQFESPANSKAHKRTTAKEIMRQL-----ARVDYLVAG 179

Query: 231 VGGGSNAIGMFADF-INETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQT 289
           VG G    G+            ++ VEP             L  GR G            
Sbjct: 180 VGTGGTITGVGEALKRKRPATNVVAVEP--------WRSPVLSGGRPG------------ 219

Query: 290 EDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPAL 349
                  +++I         G   + LN +         D EA+   + +   EG+   L
Sbjct: 220 -------AHTIQG----IGAGFVPSALNISVIDLVFKAKDWEAVAYARDMAATEGVAVGL 268

Query: 350 ESSHALAHALKMMRENPDKEQLLVVNL 376
            +  AL   + + R   D  + ++V L
Sbjct: 269 SAGAALCAGVSLARAVNDSSKTVLVIL 295


>UniRef50_B0R722 Threonine ammonia-lyase n=12 Tax=cellular organisms
           RepID=B0R722_HALS3
          Length = 410

 Score = 71.5 bits (174), Expect = 6e-11,   Method: Composition-based stats.
 Identities = 67/343 (19%), Positives = 112/343 (32%), Gaps = 59/343 (17%)

Query: 55  RPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQA--LLAKRMGKTEIIAETGA 112
           R T L      +  T   +  K E     G+ K      +   L A +     + A   A
Sbjct: 19  RHTPLEYSHTFSDLTGADVRPKLECFQRTGSFKIRGATNRIRTLSADQQDAGVVTAS--A 76

Query: 113 GQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIP-------VHSGSAT 165
           G H    ALA++  G+  ++ M       +       +  GAEV+          + +  
Sbjct: 77  GNHAQGVALAASRSGVDSKVVMPESAPISKIKAT---KSYGAEVVLHGADYDDAQAHAHE 133

Query: 166 LKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPD 225
           L+ A     R +  +++  + M G               Q  +G E  A          D
Sbjct: 134 LEAA---EGRTYVHAFDDEYIMAG---------------QGTLGLEIAADCPTV-----D 170

Query: 226 AVIACVGGGSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRV-GIYFGMK 283
            V+  +GGG    G+      E  +V +IGV+  G           L  G+   +     
Sbjct: 171 TVVVPIGGGGLISGVATALKGELDDVRVIGVQAEG----ASTVARSLDKGQPQAVDHVDT 226

Query: 284 APMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHE 343
                           I+ G+    VG Q   +      + V+++DDE   A   L    
Sbjct: 227 ----------------IADGIAVRQVGAQTFPVIQEHVDEVVTVSDDEIATALVLLLERG 270

Query: 344 GIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFT 386
             +     + ALA  L+   E  D E ++     G  D ++ T
Sbjct: 271 KTLVEGAGATALAAVLEDKFEYADGETIVPALCGGNIDLNLLT 313


>UniRef50_D2B021 Pyridoxal-5'-phosphate-dependent protein beta subunit n=10
           Tax=Bacteria RepID=D2B021_STRRD
          Length = 392

 Score = 71.1 bits (173), Expect = 6e-11,   Method: Composition-based stats.
 Identities = 69/325 (21%), Positives = 114/325 (35%), Gaps = 31/325 (9%)

Query: 70  NTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLK 129
              ++ K E      + K   +       +  G+T ++ E  +G  G + A  +A  G+ 
Sbjct: 88  GLRVHFKLEWFNPTSSFKDRGITVMISHLRGQGETHVL-EDSSGNGGSSVAAYAAAAGIH 146

Query: 130 CRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLG 189
            +I + A     +   + + R  GA++  V      + D   EA+R        +H    
Sbjct: 147 AKIIVPAATSAAK---ILQARAYGAQIELVEGTREQVSD---EAIRQSEQIPYASH---- 196

Query: 190 TAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETN 249
                HP+     +  + I  E          R PD ++   G GSN +G    F     
Sbjct: 197 ---NWHPFF---LQGTKTIAYEM---WESLGFRAPDNIVLVAGAGSNILGCDIAFSELLE 247

Query: 250 VGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSV 309
              I   P    +   EH A +     GI    + P + T    I E  SI+  +  P  
Sbjct: 248 ARQIDRRPKLL-VGQPEHWATIADAVNGIDPRSRGPRVPT----IAEGASIANPVRLPET 302

Query: 310 GPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALK-MMRENPDK 368
               A   S G    V++T+D+   A + L    G+     SS A A     M       
Sbjct: 303 --VEAIRRSGG--AAVAVTEDQIRTAVRKLASR-GLYAEPTSSVAAAALDHFMADGAIGP 357

Query: 369 EQLLVVNLSGRGDKDIFTVHDILKA 393
           ++  VV L+G G K    +  +   
Sbjct: 358 DETTVVILTGAGLKSAEKMAAVFDT 382


>UniRef50_Q10725 Phenylserine dehydratase n=62 Tax=Proteobacteria RepID=FSDH_BURPI
          Length = 326

 Score = 71.1 bits (173), Expect = 6e-11,   Method: Composition-based stats.
 Identities = 74/349 (21%), Positives = 115/349 (32%), Gaps = 50/349 (14%)

Query: 35  AQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQ 94
              D    A     LK +  R T +    +      T +  K E L   G  K       
Sbjct: 8   TLPDLSAIAGLRARLKQWV-RTTPVFDKTDFEPVPGTAVNFKLELLQASGTFKARGAFSN 66

Query: 95  ALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGA 154
            L      +   +    AG H V  A A+  LG+  ++ M           V   R  GA
Sbjct: 67  LLALDDDQRAAGVTCVSAGNHAVGVAYAAMRLGIPAKVVMIKT---ASPARVALCRQYGA 123

Query: 155 EVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTI-VREFQRMIGEETK 213
           EV+   +G     D  +        S E   ++       HP+           +G E  
Sbjct: 124 EVVLAENGQTAF-DTVHR-----IESEEGRFFV-------HPFNGYRTVLGTATLGHE-- 168

Query: 214 AQILEREGRLPDAVIACVGGGSNAIGMFADF-INETNVGLIGVEPGGHGI--ETGEHGAP 270
              LE+ G L DAVI  +GGG    G+     +      +IGVEP G      + E G P
Sbjct: 169 --WLEQAGAL-DAVIVPIGGGGLMAGVSTAVKLLAPQCQVIGVEPEGADAMHRSFETGGP 225

Query: 271 LKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAY-LNSTGRADYVSITD 329
           +K G            MQ+    +   ++            Q++Y L        V ++D
Sbjct: 226 VKMGS-----------MQSIADSLMAPHT-----------EQYSYELCRRNVDRLVKVSD 263

Query: 330 DEALEAFKTLCLHEGIIPALESSHALAHAL-KMMRENPDKEQLLVVNLS 377
           DE   A + L     +      + A A  +  +  E   K   +++  +
Sbjct: 264 DELRAAMRLLFDQLKLATEPACATATAALVGGLKAELAGKRVGVLLCGT 312


>UniRef50_B1KBC9 Cysteine synthase n=7 Tax=Bacteria RepID=B1KBC9_BURCC
          Length = 312

 Score = 71.1 bits (173), Expect = 6e-11,   Method: Composition-based stats.
 Identities = 65/342 (19%), Positives = 121/342 (35%), Gaps = 58/342 (16%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE----IIAETGA 112
           T+L   +++       L++K E     G+ K    L      +R G+ +    ++  TG 
Sbjct: 15  TSLVPLRHVVPKNGARLFVKLESQNPTGSMKDRIALAMIEAPERDGRLKPGGAVVEYTG- 73

Query: 113 GQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSAT-----LK 167
           G  GV+ AL  A+      +++ + D   +   +  MRL+GA++  V S +        K
Sbjct: 74  GSTGVSLALVCAVKRHP--LHLVSSDAFSKE-KLDHMRLLGAKLTLVPSDNGKQTEKLTK 130

Query: 168 DACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAV 227
           D   EA R            +    G +    +    Q     +   +I E+ G   D  
Sbjct: 131 DMIREAHR------------IAGETGAYITAQMENTDQLDAYTKMADEIWEQTGGRLDGF 178

Query: 228 IACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPM 286
           +  VG  ++  G+       +  + + GVEP    + +G  G    H   GI  G   P+
Sbjct: 179 VQSVGTAASLRGISRRLREHDARIRIAGVEPAESAVLSG--GPTGAHKIDGIGAGYVVPL 236

Query: 287 MQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGII 346
            +                    +  +          + VS  D  A+ AF+     EG+ 
Sbjct: 237 WRD------------------GIADEL---------ERVSTEDARAM-AFRLAAE-EGLF 267

Query: 347 PALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVH 388
               +   +  AL++  E    +  +V  +   G K + +  
Sbjct: 268 CGTSTGANVTGALRLA-ERLGPDATIVTIMCDTGMKYLKSFA 308


>UniRef50_O34476 Probable cysteine synthase n=7 Tax=Bacteria RepID=CYSM_BACSU
          Length = 311

 Score = 71.1 bits (173), Expect = 7e-11,   Method: Composition-based stats.
 Identities = 58/333 (17%), Positives = 111/333 (33%), Gaps = 66/333 (19%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE---IIAETGAG 113
           T L +   +       +YLK E     G+ K        + A++ G  +   +I E  +G
Sbjct: 15  TPLVRLNRLQPENAAQVYLKLEFFNPSGSVKDRAAYQMIIEAEQNGLLKPGSVIIEPTSG 74

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSG---SATLKDAC 170
             G+  A+ +A  G K  + M     +     +  ++  GAEV+          ++K A 
Sbjct: 75  NTGIGLAMNAAARGYKAILVMPDTMTKE---RINLLKAYGAEVVLTPGEERMPGSIKKA- 130

Query: 171 NEALRDWSGSYETAH--YMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVI 228
               ++ +     ++        A P          ++    E    I E  G+   A +
Sbjct: 131 ----KELAEQIPNSYIPMQFDNTANPDA-------HRKTTAPEIARAI-EEIGKPLGAFV 178

Query: 229 ACVGGGSNAIGMFADFINE------TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGM 282
           A     S+  G       E       ++ +  VEP G  + +G  G P  H  VG   G 
Sbjct: 179 A-----SSGTGGTITGTGEALKELFPDITVHVVEPAGSPVLSG--GKPGAHKLVGTSPGF 231

Query: 283 KAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLH 342
             P++  +                                + + I+D++A    + L   
Sbjct: 232 IPPILNEDVYD-----------------------------EIIKISDEDAYTTTRRLAAE 262

Query: 343 EGIIPALESSHALAHALKMMRENPDKEQLLVVN 375
           EGI+    S  A   A++  +     + ++ + 
Sbjct: 263 EGILVGPSSGAACFAAIETAKRLSPDKVVVCMT 295


>UniRef50_UPI000180BB5B PREDICTED: similar to Serine racemase n=2 Tax=Ciona intestinalis
           RepID=UPI000180BB5B
          Length = 338

 Score = 71.1 bits (173), Expect = 7e-11,   Method: Composition-based stats.
 Identities = 42/205 (20%), Positives = 74/205 (36%), Gaps = 26/205 (12%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTN---QVLGQALLAKRMGKTEIIAETGAG 113
           T L +C  I+      ++LK E+    G+ K       L  ++  K      +I  + +G
Sbjct: 35  TPLMQCSAISELAGCNVFLKTENFQKTGSFKIRGATNALSHSV--KEDAIQCVITRS-SG 91

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
            HG A A  +  +G+   I M    ++ +      +R  G  ++         K      
Sbjct: 92  NHGQAIAYVAKSMGIPAYIIMSNTALKCK---KDAIRSYGGIIVEGKPQLEHRKKITEHL 148

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
           L++  G +      + +   PH     V   Q  +  E   Q         DA++A VGG
Sbjct: 149 LKEKGGIF------IHSGQNPH-----VIAGQGTLAMEMLEQNPNL-----DAIVAPVGG 192

Query: 234 GSNAIGMFADFIN-ETNVGLIGVEP 257
           G    G+       +  + +  VEP
Sbjct: 193 GGLISGVAIAAKALKPYIKIYAVEP 217


>UniRef50_C5DI11 Cysteine synthase n=19 Tax=Saccharomyceta RepID=C5DI11_LACTC
          Length = 391

 Score = 71.1 bits (173), Expect = 7e-11,   Method: Composition-based stats.
 Identities = 68/346 (19%), Positives = 124/346 (35%), Gaps = 57/346 (16%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE-----IIAETG 111
           T + K ++++  T   +Y K E    GG+ K    LG    A+R G        ++ E  
Sbjct: 51  TPVIKIKSLSKATGCEVYAKMELCNPGGSAKDRVALGIVRAAERQGLLRPGFPDVVFEGT 110

Query: 112 AGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPV-HSGSATLKDAC 170
           +G  G++ A     LG +  I +       +      +  +GA++  V  +G    +   
Sbjct: 111 SGSTGISIATICNALGYRAHISLPDDTSAEKL---ALLESLGAQINKVRPAGIVDPEQYV 167

Query: 171 NEALRDWSGSYETAHYMLGTAAGPHPYP---------TIVREFQRMIGEETKAQILEREG 221
           N A R  +   +       +  G H                 +Q   G E   Q+  R  
Sbjct: 168 NAAQRACNQLNQ-------SGDGSHRGVFADQFENDANWRVHYQGT-GPEIYRQLDGRI- 218

Query: 222 RLPDAVIACVGGGSNAIGMFADFINET---NVGLIGVEPGGHGIETGEHGAPLKHGRVGI 278
              DA IA  G G    G+   F+ E     + ++  +P G G                +
Sbjct: 219 ---DAFIAGCGTGGTIAGVAR-FLKEKLGGRLRVVLADPQGSGFYN------------RV 262

Query: 279 YFGMKAPMMQTEDGQIEESYSISAGLDFPSVG-PQHAYLNSTG---RADYVSITDDEALE 334
            FG    +M     Q               +G  +  +  S G     D   +TD +A+ 
Sbjct: 263 KFG----VMYDRVEQEGTRRRHQVDTIVEGIGLNRITHNFSQGEPYIDDAERVTDGQAVR 318

Query: 335 AFKTLCLHEGIIPALESS-HALAHALKMMRENPDKEQLLVV-NLSG 378
             K L +++G+     ++ +A+A A+K+    P   +++++   SG
Sbjct: 319 MAKFLSVNDGLFIGSSTAINAVA-AVKVAESLPPGSRIVIIACDSG 363


>UniRef50_B0T581 Cysteine synthase n=51 Tax=Bacteria RepID=B0T581_CAUSK
          Length = 479

 Score = 71.1 bits (173), Expect = 7e-11,   Method: Composition-based stats.
 Identities = 70/331 (21%), Positives = 124/331 (37%), Gaps = 42/331 (12%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE---IIAETGAG 113
           T + + +N+  G    L+LK E+   GG+ K          A+  G  +    I E  AG
Sbjct: 22  TPMMEVRNLDTG-PCRLFLKLENQNPGGSIKDRVARSMIEAAEADGSLKPGGTIIEATAG 80

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSG-SATLKDACNE 172
             G+  A  + L G K  I +    + R+   +  +R MG +V    S       +   +
Sbjct: 81  NTGLGLAQVATLKGYKL-ILIVPDKMAREK--ILHLRAMGVDVRLTRSDVGKGHPEYYQD 137

Query: 173 ALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVG 232
             +  + S   A Y           P      +     E   Q+    G   DA++  VG
Sbjct: 138 MAQTLAQSIPGAIY-----VNQFENPANPLAHETTTAPEIFEQM----GGDIDAMVVGVG 188

Query: 233 GGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDG 292
            G    G+   F+ + +     V     G    ++ A   +G  G      + +++    
Sbjct: 189 SGGTLTGV-GRFMAKHSPKTEMVLADPVGSILCDYVATGTYGEAG------SWIVEGIGE 241

Query: 293 QIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESS 352
                  ++A +DF     +HAY          SI+D E+++  + L   EGI+    S 
Sbjct: 242 DFIP---VNAEMDFV----KHAY----------SISDRESVDTARLLLRKEGILAGSSSG 284

Query: 353 HALAHALKMMRENPDKEQLL-VVNLSGRGDK 382
             LA AL+  RE  + ++++ +V  +G    
Sbjct: 285 TLLAAALRYCREQTEPKRVVTLVCDTGSKYL 315


>UniRef50_D1TEY8 Pyridoxal-5'-phosphate-dependent protein beta subunit n=1
           Tax=Burkholderia sp. CCGE1002 RepID=D1TEY8_9BURK
          Length = 329

 Score = 70.7 bits (172), Expect = 8e-11,   Method: Composition-based stats.
 Identities = 77/344 (22%), Positives = 117/344 (34%), Gaps = 71/344 (20%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQAL-LAKRMGKTEIIAETGAGQH 115
           T L +   +       +YLK E L   G+ K    L + L L ++     II  + +G H
Sbjct: 25  TPLLRESKMDKSLGCHVYLKPEMLQVTGSFKIRGALNKILSLTRKELDKGIITSS-SGNH 83

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
           G A A A  LLG+   + +       +  N    + MGA+VI                  
Sbjct: 84  GQACAYAGQLLGIHTTVIVPNDAPSLKVEN---AKSMGADVI------------------ 122

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTI-------VREFQRMIGEETKAQILEREGRLPD--- 225
            W  SYE     +      H Y  +       V   Q  IG E           LPD   
Sbjct: 123 LWDRSYEERWKKVHADVEEHGYTIVHNYEDFDVMAGQGTIGLEIIE-------DLPDVDT 175

Query: 226 AVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAP 285
            ++   GGG  +    A   +   + +IGV+                             
Sbjct: 176 VLVPIGGGGLISGISIAIKESNARIKVIGVQAAA----------------------CCPY 213

Query: 286 MMQTEDGQIEESYS---ISAGL--DFPSVGPQHAYLNSTGRADYVSITDDEAL-EAFKTL 339
            M  + G+  ++ S   I+ GL  +FP     H Y       D + I  +EA+ EA +T+
Sbjct: 214 YMSRQAGERTKAASMRTIADGLACNFPG---NHPYPIIEKYVDDIVIVSEEAIEEAVRTV 270

Query: 340 CLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKD 383
                ++    S   +A  L         E++ VV  SG  D D
Sbjct: 271 ANDAKLVAEPSSCVGIAALLSGAVRTGADEKVCVVLTSGNWDID 314


>UniRef50_Q2RHT1 Cysteine synthase n=6 Tax=Bacteria RepID=Q2RHT1_MOOTA
          Length = 306

 Score = 70.7 bits (172), Expect = 8e-11,   Method: Composition-based stats.
 Identities = 66/323 (20%), Positives = 121/323 (37%), Gaps = 52/323 (16%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE---IIAETGAG 113
           T + +   +       +YLK E    GG+ K    L     A+  G+ +    I E  +G
Sbjct: 14  TPILRLNRLVED-GMEVYLKIEFFNPGGSVKDRIALSMITAAEADGRLKPGDTIVEPTSG 72

Query: 114 QHGVASALASALLGLKCRIYMGAK-DVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNE 172
             G+  A+ +A+ G +  + M     +ER       +   GAE +    G+  +K A ++
Sbjct: 73  NTGIGLAMVAAVRGYRLILVMPETMSIER----RKLLAAYGAEFVLTP-GNLGMKGAVDK 127

Query: 173 ALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVG 232
           A      +    ++M      P   P I    ++    E   Q+        DA +A VG
Sbjct: 128 ANELVRENP--GYFMPQQFENPA-NPAI---HRQTTAREILEQM----DGKVDAFVAGVG 177

Query: 233 GGSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTED 291
            G    G+      E   V ++ VEP    + +G    P  H   GI  G   P+++ E 
Sbjct: 178 TGGTLTGVGEVLKKEIPGVRIVAVEPAASPVLSGGQPGP--HKIQGIGAGFVPPVLRREV 235

Query: 292 GQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALES 351
                                          + +++T+++A+E  + L   EG++  + S
Sbjct: 236 VD-----------------------------EIITVTNEDAMETARRLAREEGLLVGISS 266

Query: 352 SHALAHALKMMRENPDKEQLLVV 374
             A   AL++ R     +++L +
Sbjct: 267 GAAAFAALQVARRLGRGKRVLAI 289


>UniRef50_Q8YXP3 Cysteine synthase n=2 Tax=Nostoc sp. PCC 7120 RepID=Q8YXP3_ANASP
          Length = 365

 Score = 70.7 bits (172), Expect = 9e-11,   Method: Composition-based stats.
 Identities = 66/341 (19%), Positives = 114/341 (33%), Gaps = 54/341 (15%)

Query: 58  ALTKCQNITAGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK---TEIIAETGAG 113
            + K +NI+        +LK E    GG+ K    +     A+  G       I E+ +G
Sbjct: 40  PIVKLRNISPVCAIAECFLKLESCNPGGSIKEKNAVYLVTCAEEEGLLVPGGTIIESSSG 99

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVH----SGSATLKDA 169
             GV  A+  A+ G +  I     D +   P    ++  GAE++ V       S +++ A
Sbjct: 100 NFGVGLAMVGAVRGYRVIIV---VDAKTPPPFRRMLKAYGAELVDVPLHEADESGSMQKA 156

Query: 170 CNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIA 229
             +  ++ + +   A Y        H  P            E +A   +      DAV+ 
Sbjct: 157 RMKRAKELAATIPDAWYPC-----QHLNPLNTEAHSYYTAREIEAHFADEL----DAVVV 207

Query: 230 CVGGGSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQ 288
            V      +G+          + +IGV+  G  I           G        K   M 
Sbjct: 208 GVSTAGQIMGIARYLRPRFPKIRIIGVDVVGSVI----------MGTS-----AKPYKMT 252

Query: 289 TEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPA 348
                        + LD                     + +D A      L   EG++  
Sbjct: 253 GIGLSFFPPNLDLSLLD-----------------RAYIVPEDLAYSVCHALARREGLLLG 295

Query: 349 LESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHD 389
             +   +A  L + RE     ++L++N   RGD+ + TV+D
Sbjct: 296 ASTGAIVAGGLHLARELGRGARILMINPD-RGDRYLETVYD 335


>UniRef50_P71128 Cysteine synthase B n=12 Tax=Campylobacter RepID=CYSM_CAMJE
          Length = 299

 Score = 70.7 bits (172), Expect = 9e-11,   Method: Composition-based stats.
 Identities = 57/325 (17%), Positives = 113/325 (34%), Gaps = 58/325 (17%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQV---LGQALLAKRMGKTEIIAETGAG 113
           T +   +         ++ K E L    + K       +  AL +K++ +   I E  +G
Sbjct: 14  TPIIHLKKF----GINVFAKCEFLNPSHSIKDRAAFEMIKDALDSKKINQDTTIVEATSG 69

Query: 114 QHGVASALASALLGLKCRIYMGAK-DVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNE 172
             G++ A+  A LGLK    M     +ER+      + L GA +    +    +K A ++
Sbjct: 70  NTGISLAMICADLGLKFIAVMPESMSLERRKM----ITLFGARLELTPANLG-MKGAVDK 124

Query: 173 ALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVG 232
           A  +   +   +              +     ++    E    +        D  +A  G
Sbjct: 125 A-NEILLNTPNSFM-----VSQFENISNKNAHRKNTALEILRDLDNEL----DIFVAGFG 174

Query: 233 GGSNAIGMFADFINE--TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTE 290
            G    G+  + + E    V ++GVEP         +   L  G  G      +  +Q  
Sbjct: 175 TGGTISGV-GEILKEKLEKVHIVGVEP--------LNSPLLSKGEAG------SHKIQGI 219

Query: 291 DGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALE 350
                                  A LN     + +++++++A+   K L    G++  + 
Sbjct: 220 GANFIP-----------------AILNKEVIDEVITVSNEDAINTAKELAKS-GLMVGIS 261

Query: 351 SSHALAHALKMMRENPDKEQLLVVN 375
           S   +  A  + ++ PDK  L ++N
Sbjct: 262 SGANVFAASMLAKKFPDKRILTMLN 286


>UniRef50_Q44051 Transposon Mu dl-R insertion site. (Fragment) n=1 Tax=Escherichia
          coli RepID=Q44051_ECOLX
          Length = 45

 Score = 70.7 bits (172), Expect = 9e-11,   Method: Composition-based stats.
 Identities = 40/40 (100%), Positives = 40/40 (100%)

Query: 1  MTTLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPE 40
          MTTLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPE
Sbjct: 6  MTTLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPE 45


>UniRef50_P50867 Cysteine synthase n=103 Tax=cellular organisms RepID=CYSK_EMENI
          Length = 370

 Score = 70.7 bits (172), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 62/336 (18%), Positives = 108/336 (32%), Gaps = 56/336 (16%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE---IIAETGAG 113
           T L + + ++  T + +  K E    GG+ K    L     A+  G  +    + E  AG
Sbjct: 43  TPLIRLKRLSEETGSNILAKAEFQNPGGSVKDRAALYVVKDAEERGLLKPGGTVVEGTAG 102

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
             G+  A      G K  IYM     + +   +  +RL+GAEV PV + +    +  N  
Sbjct: 103 NTGIGLAHVCRSKGYKLVIYMPNTQSQGK---IDLLRLLGAEVYPVPAVAFDNPENYNHK 159

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
            R  + S + A +               R      G E  AQ     G   DA     G 
Sbjct: 160 ARRHAESLDNAVWT-----NQFDNTANRRAHIETTGPEIWAQ----TGGKLDAFTCSTGT 210

Query: 234 GSNAIGMFA-----------DFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGM 282
           G    G+              F+ +    ++       G      G+ +  G   I  G 
Sbjct: 211 GGTLAGITYYLKQASGGRVKSFLADPPGSVLHSYIQSGGKLVERSGSSITEG---IGQGR 267

Query: 283 KAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLH 342
               +Q + G ++ S +IS                           D++ +E        
Sbjct: 268 ITDNLQPDVGTLDGSLNIS---------------------------DEKTIEMIYRCLDE 300

Query: 343 EGIIPALESSHALAHALKMMRENPDKEQLLVVNLSG 378
           EG+     S+  +  A ++  +      ++ +   G
Sbjct: 301 EGLYLGASSALNVVAAKEVAEKLGKGSTVVTILADG 336


>UniRef50_A6WWN6 Threonine synthase n=3 Tax=Rhizobiales RepID=A6WWN6_OCHA4
          Length = 413

 Score = 70.3 bits (171), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 73/350 (20%), Positives = 120/350 (34%), Gaps = 46/350 (13%)

Query: 57  TALTKCQNITAGTNTT-LYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           T L + + I A      L++K E      +HK          A   G + ++A + +G  
Sbjct: 84  TPLLRSERIGAVIGVPNLFIKNEGYNPTWSHKDRFSTVAVTAAVEAGAS-VVATSSSGNA 142

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSAT---LKDACNE 172
           G + A  +A  GL+C +   A       P + +++  GA+++P  +       L      
Sbjct: 143 GASLAAYAARAGLECIV---ATIAGSAGPMLSQIQKYGAKIVPFENKQERWPFLAKGVER 199

Query: 173 ALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVG 232
               W  +    H ++G+    HP      E  + +  E   Q     G++PD     V 
Sbjct: 200 YG--WFATSPYRHPVVGS----HPIG---IEGYKTLAYEIIEQF---NGKVPDWCAFPVC 247

Query: 233 GGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDG 292
            G    G +  F      GLI   P     E                 G  A  ++T   
Sbjct: 248 YGDAIAGAWLGFHELMVDGLIARMPRLLAAE---------------AHGSLATALETRSD 292

Query: 293 QIEE------SYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGII 346
           QI +      + ++S G    +     A   S G A  V+     A +  + +   EG+ 
Sbjct: 293 QIPDMAASFNALAVSVGATRSTYQALKALRASNGTAIPVANDGLVAFQ--ERIAASEGVF 350

Query: 347 PALESS---HALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
             L S     A+A A +      D+  + VV  SG  D D       L  
Sbjct: 351 LELSSVMPLAAIATARRRNIIRGDESAVAVVTASGLKDIDKSISEKPLPR 400


>UniRef50_Q9R6V6 ANL49 n=1 Tax=Synechococcus elongatus PCC 7942 RepID=Q9R6V6_SYNE7
          Length = 329

 Score = 70.3 bits (171), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 66/334 (19%), Positives = 113/334 (33%), Gaps = 62/334 (18%)

Query: 57  TALTKCQNITAGTNT--TLYLKREDLLHGGAHKTNQVLGQALLAKRMG---KTEIIAETG 111
           T L + Q           + LK E L   G+ K    L     A+  G       + E  
Sbjct: 15  TPLVRLQETAQQYGAIAEVLLKLEYLNPLGSVKDRTALSLIQSARSQGLITAGTTLIEPT 74

Query: 112 AGQHGVASALASALLGLKCRIYM-GAKDVERQSPNVFRMRLMGAEVIPVHSGSATLK-DA 169
            G  G+  A A+A   L+  + M      ER    +   +L+GA+V+   +  A L   A
Sbjct: 75  TGNTGIGLAFAAAAEQLRLILVMPDRVSAER----IRLAKLLGAKVVLTPAAEAMLGCIA 130

Query: 170 CNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIA 229
             +AL+                      P      Q   G E      + +G + D V+A
Sbjct: 131 KAQALQQQIPDSV--------ILQQFQNPANPSIHQATTGPEI---WRDTDGEV-DIVVA 178

Query: 230 CVGGGSNAIGMFADFINETNVGL--IGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMM 287
            VG G   +G+ + ++      L  I V+P             L  G  G          
Sbjct: 179 GVGTGGTLMGI-SRYLKPLRPRLQSIAVQPA--------RSPVLSGGAAG---------- 219

Query: 288 QTEDGQIEESYSISAGLDFPSVGPQ-HAYLNSTGRA-DYVSITDDEALEAFKTLCLHEGI 345
                Q+              +GP   + L       + +S  +++A+   +T    EGI
Sbjct: 220 ---SHQLT------------GMGPNFVSPLVDRSLIDEILSAYEEDAIAVIRTCAAREGI 264

Query: 346 IPALESSHALAHALKMMRENPD-KEQLLVVNLSG 378
              + S   +  AL++ +   +  ++++ V  SG
Sbjct: 265 PLGVSSGAIVWAALQVAKRPENAGKRIVAVCPSG 298


>UniRef50_B9L6H6 Cysteine synthase n=2 Tax=Nautiliaceae RepID=B9L6H6_NAUPA
          Length = 272

 Score = 70.3 bits (171), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 46/207 (22%), Positives = 81/207 (39%), Gaps = 31/207 (14%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T + + +NI+        +K E     G+ K    L     A   G  EI+  T +G  G
Sbjct: 4   TPIYQLKNIS--------VKLEYKNPAGSIKDRPALFMIRDAINKGYKEIVEAT-SGNTG 54

Query: 117 VASALASALLGLKCRIYMGAK-DVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
           +A A  +   G+K  I+M     +ERQ      ++L GA +I       ++ D+ NEA +
Sbjct: 55  IALAFYAKKFGIKATIFMPESYSIERQK----LLKLYGANLILTK---GSIADSINEA-K 106

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
           +++  ++  +            P   +  Q +   E   Q+ +      D  +A VG G 
Sbjct: 107 EYAQKHKALY------TNQFSNPLNAKS-QEITAFEILNQVQKI-----DCFVAGVGSGG 154

Query: 236 NAIGMFADFINETNVGLIGVEPGGHGI 262
              G+    +    V +I VE     +
Sbjct: 155 TITGIAR-ILKPLGVKIIAVESENSPV 180


>UniRef50_Q2S090 Threonine dehydratase n=6 Tax=cellular organisms RepID=Q2S090_SALRD
          Length = 470

 Score = 70.3 bits (171), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 70/342 (20%), Positives = 115/342 (33%), Gaps = 49/342 (14%)

Query: 55  RPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTN---QVLGQALLAKRMGKTEIIAETG 111
           R T +  C +++  +     LK E L   G+ KT      L Q       G    +    
Sbjct: 88  RKTPIDSCHSLSELSGAVAILKMEHLQRTGSFKTRGAYNKLAQV----ASGTVGRVVAAS 143

Query: 112 AGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACN 171
           AG H    ALA+  + L   I M     + +   V   R  GA+V        T ++A  
Sbjct: 144 AGNHAQGVALAATTVDLPSTIVMPRNAPQAK---VDATRGYGADVELT---GDTFQEAMT 197

Query: 172 EALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACV 231
            A R+ +   +            +  P IV   Q  +G E   Q+        D VIA +
Sbjct: 198 RA-RELARGDDALF------VHAYDDPDIVA-GQGTLGFELYEQVP-----DVDTVIAPI 244

Query: 232 GGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTE 290
           GGG    G      +   +V ++GV+  G                     G+  P+    
Sbjct: 245 GGGGLIGGTSMALADIAPDVRVVGVQAAGAATVPQSLAK-----------GVPVPV---- 289

Query: 291 DGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALE 350
                   +I+ G+    V      L      + +++TD E   A   L      +   E
Sbjct: 290 ----NHPDTIADGIATGGVSALTLGLIDDHVDEVITVTDGEIARAILLLLERAKQLV--E 343

Query: 351 SSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILK 392
            + A   A  +  +     + +V  L G G+ D   + ++L 
Sbjct: 344 GAGAAPVAALLSDKLDVTGETVVPLLCG-GNIDPARLQEVLD 384


>UniRef50_UPI0001926B07 PREDICTED: similar to predicted protein n=2 Tax=Hydra magnipapillata
            RepID=UPI0001926B07
          Length = 1245

 Score = 70.3 bits (171), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 49/220 (22%), Positives = 79/220 (35%), Gaps = 31/220 (14%)

Query: 56   PTALTKCQNITAGTNTTL---YLKREDLLHGGAHKTNQVLGQAL-LAKRMGK-TEIIAET 110
            PT L   Q +       +    +K E +   G+ K   VL Q L L+    K   I+   
Sbjct: 1020 PTLLGLEQQVQNELPVKIKSLSIKLESMQCTGSFKARGVLSQFLELSSEDCKNKRILVTM 1079

Query: 111  GAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDAC 170
             AG +G A A  S    +   + M     E        ++  GA+V+      + L D  
Sbjct: 1080 SAGNYGKAFAYISGEENMPAVVCMPESAPE---DRRETIKSFGAKVLL--CSRSELMDTV 1134

Query: 171  NEALRDWSGSYETAHYMLGTAAGPHPYPTI--VREFQRMIGEETKAQILEREGRLPDAVI 228
            N        ++   H     +   H +  I  ++      G E   Q+     + PD ++
Sbjct: 1135 N--------NHVKNH----NSLFLHSFDDIQLIKGHAS-AGLELVEQLP----KEPDIIV 1177

Query: 229  ACVGGGSNAIG--MFADFINETNVGLIGVEPGGHGIETGE 266
             C GGG    G  +   F   T+  + GVEP    ++T  
Sbjct: 1178 VCCGGGGFLAGVSLAVRFYGWTSTKIYGVEPDAVFMKTKS 1217


>UniRef50_C5FWS0 L-serine dehydratase n=3 Tax=Onygenales RepID=C5FWS0_NANOT
          Length = 436

 Score = 69.9 bits (170), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 46/195 (23%), Positives = 76/195 (38%), Gaps = 25/195 (12%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKT----NQVLGQALLAKRMGKTEIIAETGA 112
           T L +  +++      ++LK ++L   G+ K+    N V G A      GK        A
Sbjct: 19  TPLIESTSLSKAAGCRIFLKLDNLQPSGSFKSRGIGNLVRGHATDPANKGKRLHFFIPSA 78

Query: 113 GQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNE 172
           G  G+ +A A++ L   C +   A  V  +   + +++  GA V  V  G+   + A   
Sbjct: 79  GNAGLGAAFAASALNYPCTV---AVTVNTKPVMIKKLQQAGARV--VQHGTNLDEAAVR- 132

Query: 173 ALRDWSGSYETAHYMLGT----AAGPHPYP-TIVREFQRMIGEETKAQILEREGRLP--- 224
            +R+        H   G     A   HP+    + E    + +E   Q+   E   P   
Sbjct: 133 -MREMMKELTD-HPTPGGSEVVAIELHPFDRQHIWEGVSTMSDELAYQLPPAEENDPCLR 190

Query: 225 -----DAVIACVGGG 234
                DA+I  VGGG
Sbjct: 191 KALPCDAIICSVGGG 205


>UniRef50_B3TC39 Putative Pyridoxal-phosphate dependent enzyme n=1 Tax=uncultured
           marine microorganism HF4000_APKG10H11 RepID=B3TC39_9ZZZZ
          Length = 323

 Score = 69.9 bits (170), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 76/361 (21%), Positives = 130/361 (36%), Gaps = 77/361 (21%)

Query: 55  RPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGA-- 112
           +PT L     ++       Y+K E+ L   + K     G   L K + KT I     A  
Sbjct: 22  KPTPLRYYAELSDYLGFNSYIKHENHLPTNSFKIR---GGINLLKHLSKTNIKGVITASR 78

Query: 113 GQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNE 172
           G HG + A +S L  +KC+I                ++   AE+I          +  +E
Sbjct: 79  GNHGQSLAYSSMLENIKCKIV---VPYGNNPEKNVAIKSFNAELIE-------YGNDFDE 128

Query: 173 ALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLP--DAVIAC 230
           A R++S    T  ++      P   P +      + G     Q LE    LP  D +I  
Sbjct: 129 A-REYSEKLVTNKFLY---IHPCNEPKL------IAG--VATQTLEILTDLPEVDTIILP 176

Query: 231 VGGGSNAIG-MFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQT 289
           +GGG+   G +      +  V +IGV+                           A  +  
Sbjct: 177 LGGGTEVAGAIIVAKKLKPEVEIIGVQAEL----------------------APAYYLSW 214

Query: 290 EDGQIEESYS---ISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGII 346
           + G I ++ S   I+ GL         + +      + +++T+DE   +         II
Sbjct: 215 KTGNIVKTKSANTIADGLATKMPYELPSSIIMGNINEIITVTEDEIKRS---------II 265

Query: 347 PALESSHALAHAL---------KMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA-RGE 396
              +++H LA            K+  +  +K  +++  LSG G+ D+ T   IL   + E
Sbjct: 266 KLYQTTHNLAEGAGAASLAAGNKIKHKLKNKNVVMI--LSG-GNLDLKTFKSILNTNKNE 322

Query: 397 I 397
            
Sbjct: 323 F 323


>UniRef50_O94634 Threonine dehydratase, mitochondrial n=5 Tax=cellular organisms
           RepID=THDH_SCHPO
          Length = 600

 Score = 69.9 bits (170), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 53/180 (29%), Positives = 71/180 (39%), Gaps = 20/180 (11%)

Query: 53  AGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQ-ALLAKRMGKTEIIAETG 111
             + T LTK   I+  T   +YLKREDL    + K      + A L K+  K  +IA   
Sbjct: 110 VIKETPLTKGVVISESTGVPVYLKREDLTPVFSFKIRGAHNKMASLDKQSLKNGVIA-CS 168

Query: 112 AGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACN 171
           AG H    A ++  LG+K  I M     E +  NV   + +GA V+   +     K  C 
Sbjct: 169 AGNHAQGVAYSARTLGVKATIVMPQNTPEIKWRNV---KRLGANVLLHGANFDIAKAECA 225

Query: 172 EALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACV 231
              ++   + E  H        P   P  V   Q  IG E   QI     R  DA I C 
Sbjct: 226 RLAKE--QNLEVIH--------PFDDP-YVIAGQGTIGLEILHQIDL---RKLDA-IYCA 270


>UniRef50_UPI000180C083 PREDICTED: similar to serine dehydratase n=1 Tax=Ciona intestinalis
           RepID=UPI000180C083
          Length = 315

 Score = 69.9 bits (170), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 63/338 (18%), Positives = 125/338 (36%), Gaps = 64/338 (18%)

Query: 58  ALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGV 117
                + ++  +   +++K E+    G+ KT  +    +  K       +  +G G  G+
Sbjct: 11  PYKHSRALSKASGVEVWMKLENCQPSGSFKTRGISHMCV--KHKNSPRFVCSSG-GNAGL 67

Query: 118 ASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDW 177
           A+A +   LG+   I+     +      + +++  GA+V  V  G+     A +E  ++ 
Sbjct: 68  AAAYSGKQLGVPVTIF---VPLTTTQLVIDKLKDEGADV--VRGGA-----AWDECNQNA 117

Query: 178 SGSYETAHYMLGTAAGP---HPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGG 234
               E      G+   P   HPY             E  + I+      PD VI  VGGG
Sbjct: 118 LKFVEET----GSVYIPPFEHPYIW-----------EGNSSIIAELDSKPDLVICSVGGG 162

Query: 235 SNAIGMFADFINET--NVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDG 292
               G+    +     +V ++ VE                HG   +Y  ++A        
Sbjct: 163 GLMCGIVEGLVKRKWDDVPVLAVE---------------THGSNSLYQAVQA------GK 201

Query: 293 QIEESY--SISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGII--PA 348
           Q+      SI+  L   ++G Q   L  +       ++D++ ++        E I+  PA
Sbjct: 202 QVTLPAITSIAITLGAKTIGKQAFELTKSHPIIPCLVSDEDVVKTISQFLDDEKILVEPA 261

Query: 349 LESSHALAHALKMM------RENPDKEQLLVVNLSGRG 380
             +S A+ +  K+        +  + +++++V   G G
Sbjct: 262 CAASIAVLYNGKLKELASSNPKLGNVKKVVLVVCGGSG 299


>UniRef50_Q22B57 Threonine dehydratase family protein n=2 Tax=cellular organisms
           RepID=Q22B57_TETTH
          Length = 481

 Score = 69.9 bits (170), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 65/374 (17%), Positives = 117/374 (31%), Gaps = 58/374 (15%)

Query: 27  QLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAH 86
           +L+          +    + D+      R T LT+   ++      ++LKREDL    + 
Sbjct: 61  ELKTDLSKLCPINKIYKAYKDIRS--TVRRTPLTQSLYLSEKYGANVFLKREDLQIVRSF 118

Query: 87  KTNQVLGQ-ALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPN 145
           K    L +   L        ++  + AG H    A     +  K  I+M       +  +
Sbjct: 119 KLRGALNKFVNLTTEEKAKGVVCAS-AGNHAQGVAYCCNYMKTKGTIFMPVNAPSIKLRS 177

Query: 146 VFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPY-PTIVREF 204
           V   +  G   I V      + +  +E  R      E       ++   H Y    V E 
Sbjct: 178 V---KSWGGPYIEV----KLIGNTFDECFRAAKKYCEET-----SSTFVHAYDDDKVIEG 225

Query: 205 QRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIE 263
           Q  I  E             D +  C+GGG    G+ + F +   +  ++G EP      
Sbjct: 226 QATIAVEILEDFQGTI----DYIFICIGGGGLCAGVGSYFKHMSPDTVIVGCEPE----- 276

Query: 264 TGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVG-------PQHAYL 316
                            G  +  +  ++   E   SI+  +D  +VG          + L
Sbjct: 277 -----------------GCPSMKLAVQNNNPEPLKSINPFVDGAAVGIPGKRTHEIISNL 319

Query: 317 NSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNL 376
                     +       A   +   E I+     + A+A       E   K  + +++ 
Sbjct: 320 MPGVLLIPEGV----VCSALLDIYNAESIVVEPAGALAIAGLNYYKEELKGKNVVCIISG 375

Query: 377 SGRGDKDIFTVHDI 390
           S     D+  + DI
Sbjct: 376 SNN---DLTRMTDI 386


>UniRef50_B1ZNK1 Pyridoxal-5'-phosphate-dependent protein beta subunit n=1
           Tax=Opitutus terrae PB90-1 RepID=B1ZNK1_OPITP
          Length = 332

 Score = 69.6 bits (169), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 63/289 (21%), Positives = 96/289 (33%), Gaps = 41/289 (14%)

Query: 55  RPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQ 114
           R T       I   T   ++LKR+DL H G+ K        L      +   +    AG 
Sbjct: 23  RRTPCHLAPAIMEQTGMRVWLKRDDLQHTGSFKERGARHALLCLSAAERARGVVAASAGN 82

Query: 115 HGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEAL 174
           H +  A   A LG+K  + M       +   + R R +GAEV+       T  DA   A 
Sbjct: 83  HALGLAFHGATLGVKVIVVMPTVAPAVK---IARCRGLGAEVVL---HGRTFDDAQAFA- 135

Query: 175 RDWSGSYETAHYMLGTAAGPHPYPTI-VREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
           R ++      +         HP+  + V   Q  +  E   Q  +      D ++  VGG
Sbjct: 136 RVFAQRCGATY--------VHPFDDLRVIAGQGTLALEVLEQAPQL-----DTIVVPVGG 182

Query: 234 GSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDG 292
           G    G+         +V +I VEP                 R  +      P +     
Sbjct: 183 GGLLAGVATAVKALRPDVRVIAVEPENAACFLAA------CVRERVAPAAVLPTLAD--- 233

Query: 293 QIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCL 341
                     GL    VG     L ++   D V++ +DE   A + L  
Sbjct: 234 ----------GLAVAQVGALTYQLAASRVDDVVTVNEDELAAAIRLLAR 272


>UniRef50_A1KYC1 Serine dehydratase n=1 Tax=Aplysia californica RepID=A1KYC1_APLCA
          Length = 332

 Score = 69.6 bits (169), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 64/334 (19%), Positives = 114/334 (34%), Gaps = 55/334 (16%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T +     ++      +YLK ++L   G+ K   +          G +E +     G  G
Sbjct: 20  TPVMYSFPLSKHAGFKVYLKLDNLQPSGSFKIRGISNMIQKGIDRGDSEHVYCASGGNAG 79

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD 176
           +A+A AS  LG+ C I +     E       R+R +GAEV              +EA + 
Sbjct: 80  MAAAHASKQLGIPCTIVVPQTTPE---FVNERLRNLGAEV-------KVHGSVYDEAKKL 129

Query: 177 WSGSYETAHYMLGT-----AAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACV 231
                      LG+           +P I      +I  E+  Q+ ER    PD VI CV
Sbjct: 130 AVE--------LGSQPRCMLIPAFEHPDIWEGHASLI-NESSRQMSER----PDLVITCV 176

Query: 232 GGGSNAIGMFADF--INETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQT 289
           GGG    G+      +    V ++ +E  G         A        ++      + ++
Sbjct: 177 GGGGLLNGIVQGMRDVGWDEVPVLAMETHGANCFNAAIAA-----GEAVFIPAITSIAKS 231

Query: 290 EDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPAL 349
               I    +    L++        Y  +  R     ++D++ ++A          +   
Sbjct: 232 LGSLIVSPQT----LEY--------YKQARPRILNEMVSDNQVIDACVRFSDDHRFLVEP 279

Query: 350 ESSHALAHAL-KMMRENPD-------KEQLLVVN 375
               +LA     ++++  D       K  L+VV 
Sbjct: 280 ACGASLAAVYSNVVKQLQDSGKLGTVKSVLVVVC 313


>UniRef50_B2UPE5 Pyridoxal-5'-phosphate-dependent protein beta subunit n=1
           Tax=Akkermansia muciniphila ATCC BAA-835
           RepID=B2UPE5_AKKM8
          Length = 538

 Score = 69.6 bits (169), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 77/332 (23%), Positives = 127/332 (38%), Gaps = 46/332 (13%)

Query: 53  AGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLG-QALLAKRMGKTEIIAETG 111
            G PT L +  N+  G    +Y KREDL    A+K        A L++      I+A + 
Sbjct: 41  VGEPTPLQRL-NLP-GIKAPVYAKREDLGPIRAYKWRGAFNCMAALSQEARDKGIVAAS- 97

Query: 112 AGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAE-VIPVHSGSATLKDAC 170
           AG H    ALA+ +L     I+M     E +   V   R  G   V  +  G     D  
Sbjct: 98  AGNHAQGVALAARVLNCHATIFMPRSTPEVKQTEV---RRHGGRHVKIMLHGDCY--DET 152

Query: 171 NEALRDWSGSYETAHYMLGTAAGPHPYPTIVRE-FQRMIGEETKAQILEREGRLPDAVIA 229
             A  +++ ++             HPY  +V    Q  + +E    ++  EG    A +A
Sbjct: 153 AAAAHEYTETHGCTF--------VHPYDDLVTMAGQGTLADEV---VMSGEGPFDRAYVA 201

Query: 230 CVGGGSNAIGMFADFINE--TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMM 287
             GGG       A ++ +   ++ +IGVE    GI+       ++ GR      +     
Sbjct: 202 IGGGG--LAASVACWLKKFWPHIKVIGVE----GIDQASMKTSIEQGRRVNLDYVDVFC- 254

Query: 288 QTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIP 347
              DG       I   L +P        L      ++V++T++E  +A + +     ++P
Sbjct: 255 ---DGTAVH---IPGELTYP--------LCRELVDEFVTVTNNEVCQAIRAMWESSRVVP 300

Query: 348 ALESSHALAHALKMMRENPDK-EQLLVVNLSG 378
               + +LA  LK       K E+   V +SG
Sbjct: 301 EPSGAMSLAGFLKQWNRGEVKPEEKSFVVISG 332


>UniRef50_C9N4U4 Pyridoxal-5'-phosphate-dependent protein beta subunit n=3
           Tax=Streptomyces RepID=C9N4U4_9ACTO
          Length = 327

 Score = 69.2 bits (168), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 65/325 (20%), Positives = 111/325 (34%), Gaps = 49/325 (15%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK---TEIIAETGAG 113
           T L + +         +  K E      + K    L     A+R G       + E  +G
Sbjct: 33  TPLLELRLRDLAPGARVLAKLEFANPMSSSKDRAALYMMRAAERRGALLPGGTVIEATSG 92

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
             G++ A  +A  G +C I +        +  V  +R  GAE++   S       A  EA
Sbjct: 93  NTGISLAAFAASRGYRCVIVLPD---NATTERVKLLRAFGAEIVQTPSALG-YPGAIAEA 148

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
            R  + +  +           H     VR      G E  +  +   G    A +  VG 
Sbjct: 149 ERLHAATPGSWFPC------QHENQDNVRAHYETTGPEIHS-AVAATGSRIAAFVCAVGT 201

Query: 234 GSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDG 292
           G    G+       + +V +I VEP        E    L  G  G               
Sbjct: 202 GGTLTGIARHLKEQDPDVRVIAVEP--------EKSPILSQGYAG--------------- 238

Query: 293 QIEESYSISAGLDFPSVGPQHAYLNSTGRA-DYVSITDDEALEAFKTLCLHEGIIPALES 351
                + I  GL+    G   A         + ++++D++AL   + L + +G+   + S
Sbjct: 239 ----QHRI-PGLN----GGFVAETTDVSLIDEVLTVSDEDALVTARRLAISQGLFAGVSS 289

Query: 352 SHALAHALKMMRENPDKEQLLVVNL 376
             A A+A +++   P+    +VV L
Sbjct: 290 GAA-AYASEVVARRPELTGSVVVTL 313


>UniRef50_C5A2G0 Threonine synthase (ThrC) n=1 Tax=Thermococcus gammatolerans EJ3
           RepID=C5A2G0_THEGJ
          Length = 379

 Score = 69.2 bits (168), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 66/329 (20%), Positives = 106/329 (32%), Gaps = 41/329 (12%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T L K   +       LYLK E +    + K          A + G   +      G   
Sbjct: 67  TPLVKS-RLGDEFGIKLYLKNETVNPTWSFKDRGTFLAMSYALKAGYKTVGT-VSTGNMA 124

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATL---KDACNEA 173
            + +  +   GLK +I +     + +   V    + G EVI VH     L        E 
Sbjct: 125 ASVSAYATRFGLKAKILVSESAGDEKLKAVS---VYGGEVIRVHGDYGRLYFESLKLGER 181

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
           L  +  + +               P  +  ++  I  E   +I       PD ++     
Sbjct: 182 LGVYFMNSDN--------------PLRIEGYKS-IAFEIAEEIS------PDYILIPTSS 220

Query: 234 GSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQ 293
           G    G+   FI     GLI   P    ++           R G     +    +T    
Sbjct: 221 GGLFRGVAKGFIELYKSGLIEGLPKLIAVQAEGCSPICMAFREGREKVERFENPRTIAKA 280

Query: 294 IEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSH 353
           I   Y  S              L   G    VS++DDE  +A + L   EG+     S+ 
Sbjct: 281 IANPYPPSG-------NALLKLLREFGWG-CVSVSDDEIRKAQERLAR-EGLFVQPASAT 331

Query: 354 ALAHALKMMRENPDKEQLLVVNLSGRGDK 382
            +A   K+    P+  +++ V L+G G K
Sbjct: 332 GIAALEKL--NLPEGAKVVSV-LTGSGLK 357


>UniRef50_A6NZW4 Putative uncharacterized protein n=2 Tax=Bacteria
           RepID=A6NZW4_9BACE
          Length = 416

 Score = 69.2 bits (168), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 71/350 (20%), Positives = 116/350 (33%), Gaps = 49/350 (14%)

Query: 57  TALTKCQNITAGTNT-TLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           T L K + +        LY+K E      ++K          A+  G   +   +  G H
Sbjct: 80  TPLLKLERLGEKLGIENLYVKDESRNPTMSYKDRLCSVIITKARHDGVPAVTMAS-TGNH 138

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSP-NVFRMRLMGAEVIPVHSGSATLKDACNEAL 174
           G A+A  +A  G+ C I+     + +        M+  GA+VI   +          + +
Sbjct: 139 GAAAAAYAAAAGMPCVIF----TIPQVPDTMKTLMQAYGAKVIVTPTSLDRWTI-MGQCV 193

Query: 175 RDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPD--AVIACVG 232
           R+      +    +  A G + Y     +  + I  E   Q+       PD  +V AC  
Sbjct: 194 RELGWMPVSGF--MSPAIGSNCYG---IDGYKSIAFEIYEQL---GNAAPDFISVPACYS 245

Query: 233 GGSNAIGMFADFIN-------ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAP 285
            G    G +    +       E     +G E  G   +T   G         +     + 
Sbjct: 246 DG--LYGTYKGMADLVEMGYLEKVPQFVGAEVFGSLEQTIAAG----EENPKVVPSDWSI 299

Query: 286 MMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGI 345
                +GQ         GL+        A   S G A   S  D E ++    L   EGI
Sbjct: 300 SFSIANGQCTWQ-----GLE--------AVRKSGGYA--RSSNDKETMDMQLLLASTEGI 344

Query: 346 IPALESSHALAHALKMMRENP--DKEQLLVVNLSGRGDKDIFTVHDILKA 393
                S  +L    K+ +E      ++ + V L+  G KD  T  + L A
Sbjct: 345 YAEASSVTSLVALAKLAKEGKIAPGQKAVAV-LTSTGLKDPATTREHLPA 393


>UniRef50_D1X751 Pyridoxal-5'-phosphate-dependent protein beta subunit n=6
           Tax=Streptomyces RepID=D1X751_9ACTO
          Length = 376

 Score = 69.2 bits (168), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 73/370 (19%), Positives = 124/370 (33%), Gaps = 38/370 (10%)

Query: 16  YVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYL 75
           + P+  + A   L     S  +  EF       +    GR T L     +T   +  L  
Sbjct: 37  FAPERGV-APNALSGRVDSLWRYEEFLPLAAPPISLGEGR-TPLVP---LTDTVSAKLDY 91

Query: 76  KREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMG 135
               L+   + K    +  A LA+R+G   ++A++  G  G + A   A  GL C +++ 
Sbjct: 92  ----LMPTLSFKDRGAVMLAELARRLGPDRVVADS-TGNAGTSVAAYCARAGLPCTVFVP 146

Query: 136 AKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPH 195
                       ++R  GA ++ V  G               +       Y        H
Sbjct: 147 EGT---SPKKTEQIRAHGAHLVTVPGGREA-----TALAARAAADGPGVFYA------SH 192

Query: 196 PYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGV 255
            +        +    E      +  GRLPDA+   VG G+  +G          +GLI  
Sbjct: 193 VFNPYFLHGTKTYVYEL---WEDLGGRLPDALAVPVGNGTLLLGAALAVAELHALGLIAT 249

Query: 256 EPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGL---DFPSVGPQ 312
            P    ++           R G       P     D     S +++ G+     P     
Sbjct: 250 RPRLIAVQAEAVSPLAGAFRAGAD---DLPPADPSDPAAVVSPTLAEGIAIPRPPRARQI 306

Query: 313 HAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLL 372
            A + ++G   ++++++D   EA + L    G      +  A   A++   E       L
Sbjct: 307 LAAVRASG-GTFLTVSEDHVREAQRDLA-ARGFYVET-TGVACWAAVREGGEAVRGS--L 361

Query: 373 VVNLSGRGDK 382
           VV L G G K
Sbjct: 362 VVPLCGAGLK 371


>UniRef50_A6GJR2 Cysteine synthase n=1 Tax=Plesiocystis pacifica SIR-1
           RepID=A6GJR2_9DELT
          Length = 315

 Score = 69.2 bits (168), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 62/326 (19%), Positives = 109/326 (33%), Gaps = 48/326 (14%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHK-------TNQVLGQALLAKRMGKTEIIAE 109
           T L   + +  G    +Y+K E L  GG+ K        +    + +L    G T I  E
Sbjct: 11  TPLLPLERLARGLPNPVYVKCEHLNPGGSVKDRLARAIVDDAEARGVLRPHAGMTLI--E 68

Query: 110 TGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDA 169
             AG  G+  AL +A  G      M  K    +   +  M   GA V+   +   +  D 
Sbjct: 69  ATAGNTGMGLALVAAARGYALVCVMPEKMSVDKRRALAAM---GARVVVTKNAPPSSPDN 125

Query: 170 CNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIA 229
                R  +   +   ++          P  V       G E   Q+    GR P A ++
Sbjct: 126 FQNVARRMAE--DEGWFL----TEQFDNPVNVEVHAATTGPEILRQL----GRAPAAFVS 175

Query: 230 CVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQ 288
             G G    G+       + +  ++  +P G G+      A  + G  G      A  ++
Sbjct: 176 GAGTGGTISGVGRCLKRADPSTRVVLADPVGSGL--AGWVATGEMGPDG------AYAVE 227

Query: 289 TEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPA 348
                   +    A +D                 + VSI+D+ +    + L   EG++  
Sbjct: 228 GIGSSKAPANLHRAVID-----------------EAVSISDERSFATARALIREEGMLVG 270

Query: 349 LESSHALAHALKMMRENPDKEQLLVV 374
             +   +A AL++         ++ V
Sbjct: 271 GSAGTNVAAALELAARPELGGPVVTV 296


>UniRef50_A8MDP7 Pyridoxal-5'-phosphate-dependent protein beta subunit n=1
           Tax=Caldivirga maquilingensis IC-167 RepID=A8MDP7_CALMQ
          Length = 357

 Score = 69.2 bits (168), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 76/345 (22%), Positives = 126/345 (36%), Gaps = 62/345 (17%)

Query: 46  NDLLKNYAGRPTALTKCQNITAGTNTTL-----YLKREDLLHGGAHKTNQVLGQALLAKR 100
            +L ++   R   + +  ++  G    +     Y K E L   G+ K     G +L    
Sbjct: 49  RELSRSELTRILPVKEPLSLGEGLTPLVRRGDYYFKLEYLNPTGSFKDR---GWSLALSV 105

Query: 101 MGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVH 160
           +     + E  +G  G++ A  SA+ G++ RIY+     E +      MRL+GA V+   
Sbjct: 106 LRNDVTVVEDSSGNAGLSLAAYSAVKGVRARIYVPKTAPEAK---KRLMRLLGANVVEA- 161

Query: 161 SGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILERE 220
              AT  DA + A+           +  G   G    P  +       G +  A  L  E
Sbjct: 162 ---ATRADASSLAMS----------FTEGVYVGHSWNPFFIH------GVKLIAYELALE 202

Query: 221 GRLPDAVIACVGGGSNAIGMFADFINETNVGL-------IGVEPGGHGIETGEHGAPLKH 273
               D V+A +G G+  +G++  F     + L       I VE  G+     E    + H
Sbjct: 203 LGNIDNVVAPLGNGTLTLGLYLGFKEAEELKLIKDTPRIIAVEASGY-----EWAYSMLH 257

Query: 274 GRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEAL 333
                  G+KA +    DG I            P +      +  TG  D V + D   +
Sbjct: 258 NTP---MGVKATL---PDGIIVPQP--------PRLTQIIDAIRDTG-GDVVVVNDQGVI 302

Query: 334 EAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSG 378
           E  +      G I    +S  +  ALK +  N     ++++  SG
Sbjct: 303 EGLREGIRL-GFIIEP-TSAVVFKALKEV--NLSGTTVVILTGSG 343


>UniRef50_A7RTQ8 Predicted protein n=2 Tax=Nematostella vectensis RepID=A7RTQ8_NEMVE
          Length = 424

 Score = 69.2 bits (168), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 44/206 (21%), Positives = 65/206 (31%), Gaps = 18/206 (8%)

Query: 65  ITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASA 124
            T   +  +++KRE L   G+ K        L      K   +  T AG HG+A A    
Sbjct: 41  FTEIEDYDVFVKREYLQPTGSFKVRGARNALLTLTPEQKGRGVITTSAGNHGLALAQQGD 100

Query: 125 LLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETA 184
            LG+     M           V       A        +  ++   N A++  S      
Sbjct: 101 ELGIPV---MVLLPENVSPLKVKLCNRYNATTKLAGRNATEVR---NMAIKFESEGGCGP 154

Query: 185 HYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADF 244
            Y+           T V   Q  +G E   Q+        DA+I  VGGG    G+    
Sbjct: 155 IYI------DENENTHVISGQGTMGLEIVDQV-----EDVDAIIVPVGGGGLLAGISVAV 203

Query: 245 INE-TNVGLIGVEPGGHGIETGEHGA 269
                ++ +IGVE            A
Sbjct: 204 KTLYPDIQIIGVEAAACPSFQAAMSA 229


>UniRef50_B2YI91 Threonine synthase n=1 Tax=uncultured crenarchaeote MCG
           RepID=B2YI91_9CREN
          Length = 360

 Score = 68.8 bits (167), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 62/326 (19%), Positives = 109/326 (33%), Gaps = 38/326 (11%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEII--AETGAGQ 114
           T L             ++ K E     G+ K     G A L   +    ++   E  +G 
Sbjct: 67  TPLVDA----LVAGRRVFFKCEYANPTGSFKDR---GSATLISVLSARGVVDAVEDSSGN 119

Query: 115 HGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEAL 174
            G + A  +A  G++ R++              ++   GAE++PV    +   D    AL
Sbjct: 120 AGASFAAYAARSGMRARVF---VPDSASGLKRRQIEAYGAELVPVPGSRS---DTVAAAL 173

Query: 175 RDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGG 234
           R             G     H +             E   Q+      +P AV+A  G G
Sbjct: 174 RASEQ---------GAVYASHAHLPFNLTGYATAAFEIVEQLSA----VPGAVLAPTGQG 220

Query: 235 SNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQI 294
              +GM   F+     G I   P   G+      APL         G+    + TE   +
Sbjct: 221 GLLLGMARGFLGLKQAGAIDRVPKLVGV-QAVACAPLAAC---FEIGINGLDLVTEGKTL 276

Query: 295 EESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHA 354
            E   +   L   SV    + +  +G   +V++ + + L    +L    G      +S  
Sbjct: 277 AEGVRVRNPLRLQSV---VSSVRESGGC-FVTVDESDILPGRDSLARL-GFYVEP-TSAL 330

Query: 355 LAHALKMMRENPDKEQLLVVNLSGRG 380
           +   L+++ E      ++++  SG  
Sbjct: 331 VWKGLQLVVEQLPDPVVVILTGSGHK 356


>UniRef50_C7BSG1 Cysteine synthase n=2 Tax=Gammaproteobacteria RepID=C7BSG1_PHOAA
          Length = 303

 Score = 68.8 bits (167), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 67/332 (20%), Positives = 119/332 (35%), Gaps = 59/332 (17%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQV---LGQALLAKRMGKTEIIAETGAG 113
           T + K + I+      +Y+K E L   G+ K       L  A+   ++     I E   G
Sbjct: 10  TPIIKLEKISKDLYADIYVKLEFLNPWGSIKDRAAKSMLESAIKNGQIDSQTTIIEATTG 69

Query: 114 QHGVASALASALLGLKCRIYMGA-KDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNE 172
             G++ A   A +GLK  I M      ER+      + L+GA++I   SG     +    
Sbjct: 70  NTGISLAGICASMGLKLIIVMPEYVSEERKK----LLTLLGAKIILTPSGE----NYAGA 121

Query: 173 ALRDWSGSYETAHYML--GTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIAC 230
             +    S +  ++++  G              +Q   G E            PD  IA 
Sbjct: 122 VKKAQMLSKKANYFLVDQGNNIN-----NPQAHYQT--GNEIIN----FFNGTPDIFIAG 170

Query: 231 VGGG--SNAIG-MFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMM 287
           +G G   N IG     + ++T +  + +EP        +  A L             P+ 
Sbjct: 171 IGTGGHCNGIGNTLKKYRSDTYI--VAIEP--------KSAAVLSQ---------MTPL- 210

Query: 288 QTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDE-ALEAFKTLCLHEGII 346
                +I  ++ I             A        D V I D+  A +  + +   EG++
Sbjct: 211 ----DEINSNHGILG-----IGPGIIANTVDRHIIDEVYIIDENSAFQTTRKIIESEGLL 261

Query: 347 PALESSHALAHALKMM-RENPDKEQLLVVNLS 377
             + S  +L  A+++  RE    +++L +  S
Sbjct: 262 IGISSGASLHCAIELASREVNKGKKILTIAAS 293


>UniRef50_Q7MYV0 Cysteine synthase n=1 Tax=Photorhabdus luminescens subsp. laumondii
           RepID=Q7MYV0_PHOLL
          Length = 342

 Score = 68.8 bits (167), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 70/339 (20%), Positives = 121/339 (35%), Gaps = 62/339 (18%)

Query: 57  TALTKCQ-NITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE---IIAETGA 112
           T +       T G N  ++LK E++  GG+ K    +     A+  G+     ++ E  +
Sbjct: 14  TPVVMLNGRYTKGIN--VFLKMENINPGGSIKDRIAVAMLERAEAQGELRPGMVVIEPSS 71

Query: 113 GQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVI---PVHSGSATLKDA 169
           G   +  A+A A+ G +    +       +     +++  GAE+I      +G  T+K  
Sbjct: 72  GNTAIGLAMACAVKGYRFIAVLDRMVPAAK---RDKIKAFGAEIIFLPEFEAGKDTVKYR 128

Query: 170 CNEALRDWSGSYETAHYMLGTAAGPHPYPTIVR--EFQRMIGEETKAQILEREGRLPDAV 227
            +   ++    Y  A         P  +   V   E  R  G E    + E  G    A 
Sbjct: 129 ID-LTKEIIKVYPNAF-------SPMQFENQVNPDEHYRSTGRE----LYEIFGNNLTAC 176

Query: 228 IACVGGGSNAIGMFADFIN--ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAP 285
            A  G      G+ + ++   +  V + GVEP G  I  GE G  L  G           
Sbjct: 177 FATAGSCGTLTGI-SRYLKEKDPQVRIYGVEPVGSIIFGGEPGKYLVQG----------- 224

Query: 286 MMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGI 345
                           AGL F       + L+ T     + + D +A    + L  +EGI
Sbjct: 225 ----------------AGLAF-----IPSILDRTNIDITLKVADIDAFRVARKLARNEGI 263

Query: 346 IPALESSHALAHAL-KMMRENPDKEQLLVVNLSGRGDKD 383
           +       A++ AL ++    P    ++++  SG    D
Sbjct: 264 LIGGTGGCAVSAALNRLDDFKPGDNIVVIIPDSGERYID 302


>UniRef50_A8MA47 Pyridoxal-5'-phosphate-dependent protein beta subunit n=1
           Tax=Caldivirga maquilingensis IC-167 RepID=A8MA47_CALMQ
          Length = 343

 Score = 68.8 bits (167), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 71/351 (20%), Positives = 123/351 (35%), Gaps = 58/351 (16%)

Query: 52  YAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETG 111
           Y  R T L + + +++     +YLK E+L   G+ K   V        R G    +    
Sbjct: 32  YVIR-TPLYRSERLSSN-GLNVYLKLENLQRSGSFKVRGVFFAVHKYMRDGYEHFLT-VS 88

Query: 112 AGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACN 171
            G H VA A  +++L ++  + +       Q   V  M   GAEVI       +  +A  
Sbjct: 89  TGNHAVALAYVASILRVRATVVVPETT---QRSKVEDMERYGAEVI---KYGRSYVEAEK 142

Query: 172 EALRDWSGSYETAHYMLGTAAGPHPYPT-IVREFQRMIGEETKAQILEREGRLPDAVIAC 230
           +AL + S S +    +       H +    V      IG E    +        DA++  
Sbjct: 143 KAL-EISSSDQRIKLI-------HTFNDYYVIAGHTTIGLEILEDLP-----NVDAILIP 189

Query: 231 VGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQT 289
           +GGG+   G+     + + +  + GV+P             LK G+  +   ++      
Sbjct: 190 LGGGALPAGVSYLVRHVKPSTKVYGVQPENAPFYVL----SLKEGKPVVLSSIET----- 240

Query: 290 EDGQIEESYSISAGL-DFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPA 348
                     I+ GL   P   P             V+  D E   A   L  +E +I  
Sbjct: 241 ----------IADGLASRPGEIPFEYIRRYLDGVLLVNERDIE--RAVYVLLKYEHVI-- 286

Query: 349 LESSHALAH-------ALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILK 392
            E + A+A         +K + +      + V+  S     D+  +  IL+
Sbjct: 287 AEGAGAIAIGPIINGDLVKKLGQGGVYNVVAVITGS---HIDVERLRKILE 334


>UniRef50_O59701 Cysteine synthase 1 n=133 Tax=cellular organisms RepID=CYSK1_SCHPO
          Length = 351

 Score = 68.8 bits (167), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 65/344 (18%), Positives = 106/344 (30%), Gaps = 58/344 (16%)

Query: 53  AGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE---IIAE 109
            GR T L +   ++  T   +  K E    GG+ K          A++ GK      I E
Sbjct: 21  IGR-TPLIRLNTLSNETGCNILAKAEFQNPGGSVKDRAAYYVVRDAEKKGKLSRGGTIVE 79

Query: 110 TGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDA 169
             AG  G+  A  +   G KC IYM     + +   +  ++ +GAEV PV     +    
Sbjct: 80  GTAGNTGIGLAHIARARGYKCVIYMPNTQSQAK---IDTLKFLGAEVHPVPVAPFSNPLN 136

Query: 170 CNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIA 229
            N   R  + S   A     +          +       G E   Q         D    
Sbjct: 137 YNHQARRHAESTPNA-----SWTDQFDNVANLLSHYETTGPEIWDQTKGTV----DGFTC 187

Query: 230 CVGGGSNAIGM-----------FADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGI 278
             G G    G+            A F+ +    ++       G      G+    G   I
Sbjct: 188 STGTGGTFAGVTKYLKEKSDGRVASFVADPPGSVLYSHIKTKGKHPDNKGSSFTEG---I 244

Query: 279 YFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKT 338
             G          G ++  Y +                      D + I D++++  F  
Sbjct: 245 GQGRIT-------GNVQPVYDL--------------------IDDAMKIPDEKSINMFFR 277

Query: 339 LCLHEGIIPALESSHALAHALKMMR-ENPDKEQLLVVNLSGRGD 381
           L   EG+     S   +  A++M +   P K  + ++  SG   
Sbjct: 278 LLDQEGLFLGGSSCLNVVAAVEMAKILGPGKTVVTILCDSGHKY 321


>UniRef50_A9GRV5 Cysteine synthase n=3 Tax=cellular organisms RepID=A9GRV5_SORC5
          Length = 330

 Score = 68.8 bits (167), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 65/332 (19%), Positives = 120/332 (36%), Gaps = 50/332 (15%)

Query: 53  AGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKR---MGKTEIIAE 109
            GR T L + + +  G   T+  K E      + K          A++   +G  + I E
Sbjct: 15  IGR-TPLVRIRRVIDGARATVLAKIEGRNPAYSVKCRIGAAMVWDAEQRGVLGPGKAIVE 73

Query: 110 TGAGQHGVASALASALLGLKCRIYMGAK-DVERQSPNVFRMRLMGAEVIPVHSGSATLKD 168
             +G  G+A A A+A  G++C + M     +ER       +  +GA+++    G   +  
Sbjct: 74  ATSGNTGIALAFAAASRGIECVLSMPETMSMER---RKVLI-ALGAKLLLTP-GPKGMNG 128

Query: 169 ACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVI 228
           A  +A  +   + +   Y+L         P      +   G E    I E  G   D ++
Sbjct: 129 AIAKA--EELAASDPGRYVL---MRQFENPANPAIHETTTGPE----IWEDTGGNADVLV 179

Query: 229 ACVGGGSNAIGMFADFINETNVGL--IGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPM 286
           + VG G    G+   F       L  + VEP    +                       +
Sbjct: 180 SGVGTGGTITGVSRYFERGRGRALHSVAVEPVHSPV-----------------------I 216

Query: 287 MQTEDGQIE--ESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEG 344
            QT  GQ      + I         G     L+ +      ++++DE++   + L   EG
Sbjct: 217 SQTLAGQPLTPSPHKIQG----IGAGFVPKNLDLSFVDQVEAVSNDESIAMARRLASEEG 272

Query: 345 IIPALESSHALAHALKMMRENPDKEQLLVVNL 376
           I+  +    A+  A ++ ++   + + +VV L
Sbjct: 273 ILCGVSCGAAMVAASRLAKDAKWEGKTIVVIL 304


>UniRef50_Q3ADX2 Cysteine synthase n=10 Tax=cellular organisms RepID=Q3ADX2_CARHZ
          Length = 306

 Score = 68.8 bits (167), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 68/343 (19%), Positives = 118/343 (34%), Gaps = 67/343 (19%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG---KTEIIAETGAG 113
           T L K + +T G   T+  K E    GG+ K          A+  G   K  +I E  +G
Sbjct: 14  TPLLKLKRVTRGVKATVVAKLEYFNPGGSVKDRIAFNMIKAAEEQGLLDKDTVIIEPTSG 73

Query: 114 QHGVASALASALLGLKCRIYMGAK-DVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNE 172
             G+  A+ +A  G +  I M     VER       ++  GAE++    G   +  A N+
Sbjct: 74  NTGIGLAMVAAARGYRLIITMPETMSVER----RMLLKAYGAEIVLTP-GELGMTGAVNK 128

Query: 173 ALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQIL---------EREGRL 223
           AL + +  +  A ++      P       +     I E+T  Q+               +
Sbjct: 129 AL-ELAKEFPKA-FIPQQFENPANPEIHRKTTAIEIWEDTDGQVDIVVGGVGTGGTITGV 186

Query: 224 PDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMK 283
            + + A                 +  V +I VEP             L  G+ G      
Sbjct: 187 GEVLKA----------------KKPEVKIIAVEPA--------DSPVLSGGKPG------ 216

Query: 284 APMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHE 343
                         + I         G      N     + + +  D+A    K +   E
Sbjct: 217 -------------PHKIQG----IGAGFVPKVFNRDVVDEIIQVESDDAFAMAKKIAKEE 259

Query: 344 GIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFT 386
           G++  + S  AL  AL++ +   ++ +L+VV L   G++ + T
Sbjct: 260 GVLVGISSGAALWAALEVAKRPENEGKLIVVVLPDTGERYLST 302


>UniRef50_O05393 O-acetylserine dependent cystathionine beta-synthase n=62
           Tax=cellular organisms RepID=MCCA_BACSU
          Length = 307

 Score = 68.8 bits (167), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 69/327 (21%), Positives = 116/327 (35%), Gaps = 60/327 (18%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALL--AKRMGKTE---IIAETG 111
           T L + +N        +Y K E +  GG+      LG  L+  A   GK +   +I E  
Sbjct: 14  TPLLRLKNFDVPEGVAVYAKLEMMNPGGS--IKDRLGDMLIRDALDSGKVKPGGVIIEAT 71

Query: 112 AGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACN 171
           AG  G+  AL++   GLK  I+   +   R+   +  M+ +GA +I        ++ A  
Sbjct: 72  AGNTGIGLALSARKYGLKA-IFCVPEHFSREKQQI--MQALGASIIHTPRQDG-MQGAIQ 127

Query: 172 EALRDWSGSYETAHYML--GTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIA 229
           +A++      E ++ +L       P  Y        + +G E    + E         +A
Sbjct: 128 KAIQL-ETEIENSYCVLQFKNRVNPSTYY-------KTLGPE----MWEALDGNIHTFVA 175

Query: 230 CVGGGSNAIGMFADFINETN--VGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMM 287
             G G    G  + F+ E N  V  + VEP G  +  GE  A    G             
Sbjct: 176 GAGSGGTFAGTAS-FLKEKNPAVKTVIVEPVGSILNGGEPHAHKTEG------------- 221

Query: 288 QTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIP 347
                +    Y   +  D                 +  ++TD+ A    K     EG++ 
Sbjct: 222 --IGMEFIPDYMDKSHFD-----------------EIYTVTDENAFRLVKEAAEKEGLLI 262

Query: 348 ALESSHALAHALKMMRENPDKEQLLVV 374
              S  AL  AL+  ++      ++ V
Sbjct: 263 GSSSGAALYAALEEAKKASAGTNIVTV 289


>UniRef50_UPI00006CA830 Pyridoxal-phosphate dependent enzyme family protein n=1
           Tax=Tetrahymena thermophila RepID=UPI00006CA830
          Length = 322

 Score = 68.8 bits (167), Expect = 4e-10,   Method: Composition-based stats.
 Identities = 59/333 (17%), Positives = 99/333 (29%), Gaps = 46/333 (13%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T +  C ++       LY K E+   GG+ K+       L   +  K   +    +G HG
Sbjct: 29  TPIITCTSLNQLVGADLYFKCENFQKGGSFKSRGAANAILSLSKEQKKNGVGTHSSGNHG 88

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD 176
            A A  + +  +   I M       +  +V   +  G ++I            C   + D
Sbjct: 89  GALARMAQIFQIPSYIIMPFDAPNSKKRSV---QNYGGKIIE-----------CGATIAD 134

Query: 177 WSGSYETAHYMLGTAAGPHPYPTI-VREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
             G+ E      G     HPY    V + Q  I  E   QI +      D +I  V    
Sbjct: 135 REGTLEKTRKETGCEI-VHPYNDYRVIKGQGTIALEIYQQIQKPL----DFIITPV---- 185

Query: 236 NAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIE 295
                         +  I +        T    A     R          ++  +     
Sbjct: 186 ---------GGGGLLSGILIASKAISPSTKVIAAEPFLARDAYLS-----LISGKVEPQF 231

Query: 296 ESYSISAGLDFPSVGPQHAYLNST--GRADYVSITDDEALEAFKTLCLHEGIIPALESSH 353
              +I+ G+           +     G      + + E ++A   +     II    S+ 
Sbjct: 232 PPKTIADGIRANLGDKTFDIIKDKCDGIL---LVEEQEIVDATNLIWQRMKIIVEPTSAT 288

Query: 354 ALAHALKMMRENPDKEQLLVVNLSGRGDKDIFT 386
            LA  +K       K   LV+     G+ DI  
Sbjct: 289 VLAAVIKNKELFKGKSIALVLTG---GNTDIEY 318


>UniRef50_B1L3T1 Threonine synthase n=1 Tax=Candidatus Korarchaeum cryptofilum OPF8
           RepID=B1L3T1_KORCO
          Length = 319

 Score = 68.4 bits (166), Expect = 4e-10,   Method: Composition-based stats.
 Identities = 72/331 (21%), Positives = 119/331 (35%), Gaps = 36/331 (10%)

Query: 56  PTALTKCQNITAGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQ 114
           P  L + + I        +Y+K E     G  K          A   G   +   T  G 
Sbjct: 16  PGTLFRVRKIPIAQGWRKIYIKWEGNNPTGTQKDRAAYMHVRRAIEQGYDTVTVGT-CGN 74

Query: 115 HGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEAL 174
            G + A  + L G++  IY+ ++        V  MR   AE++ V     + +DA     
Sbjct: 75  FGASLAYFANLHGMRAVIYVPSRYTNG---RVREMRKYNAEIVYVD---GSYEDAVE--- 125

Query: 175 RDWSGSYETAHYMLGTAAGPHPYPTIVRE--FQRMIGEETKAQILEREGRLPDAVIACVG 232
           R    + +  +Y     + P    + V    F+ +       +I+   G +PD V   +G
Sbjct: 126 RSVLDAMKYGYYD----SNPGSVNSRVALESFKAI-----AYEIVAALGSVPDLVSVPMG 176

Query: 233 GGSNAIGMFADFINETNVGLIGVEPGGHGIETG---EHGAPLKHGRVGIYFGMKAPMMQT 289
            G+   G++  F    ++G+    P   G  TG   +    LK G   +    +  + +T
Sbjct: 177 NGTTLAGIYMGFREMLDMGISRKLPVMLGATTGLGNQIAETLKRGSEELVPLREDEVRET 236

Query: 290 EDGQIEESYSISAGLDFPSVGPQHAYLNSTGRA-DYVSITDDEALEAFKTLCLHEGIIPA 348
           E  +     SI A   F       A   S G A ++     DE L         EGI P 
Sbjct: 237 EYNEPLV--SIKA---FDGEYALEAIRRSGGLAFEFY----DEELLQLAEELRMEGIDPL 287

Query: 349 LESSHALAHALKMMRENPDKEQLLVVNLSGR 379
             SS +L    + +      E  + V ++GR
Sbjct: 288 PASSSSLGAIERYLEFGGYFENAVAV-VTGR 317


>UniRef50_C1ED55 Cysteine synthase n=24 Tax=cellular organisms RepID=C1ED55_9CHLO
          Length = 375

 Score = 68.4 bits (166), Expect = 4e-10,   Method: Composition-based stats.
 Identities = 69/330 (20%), Positives = 110/330 (33%), Gaps = 45/330 (13%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE---IIAETGAG 113
           T + K  +  A     +Y K E      + K    L     A++ G  +    + E  +G
Sbjct: 32  TPIVKISDRLAPKGVEVYAKAEFFNPCSSVKDRLALAVITDAEQKGLLKPGDTVVEATSG 91

Query: 114 QHGVASALASALLGLKCRIYMGAK-DVERQSPNVFRMRLMGAEVIPVHS-GSATLKDACN 171
             G+A A+  A  G  C I M     VER       MR++GA+VI     G  T   A  
Sbjct: 92  NTGIAVAMVCAQRGYNCVICMAEPFSVER----RKIMRMLGAKVIVTPKAGKGTGMVAKA 147

Query: 172 EALRDWSGSYETAHYM---LGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVI 228
           E L +     +   ++       A P              G E    + +  G+  D  +
Sbjct: 148 EELCE-----KHGWFLCRQFENDANP-------AFHASTTGPEI---LTDFAGKRLDYFV 192

Query: 229 ACVGGGSNAIGM---FADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRV-GIYFGMKA 284
              G G    G+         +T + L+  E     I +G        G   G +    A
Sbjct: 193 TGYGTGGTFQGVGRVVKAARPDTKIVLLEPEAASL-IASGTKTERKSTGAPKGSHPAFAA 251

Query: 285 PMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEG 344
             +Q             A         Q   L      + V I+  EA+E  + L   +G
Sbjct: 252 HPIQGWTPDFIPKVLEDA---------QAMDLYD----ELVPISGPEAIETAQKLASTQG 298

Query: 345 IIPALESSHALAHALKMMRENPDKEQLLVV 374
           I   +    ++A ALK+  + P    +L +
Sbjct: 299 IFTGISGGASMAGALKVAAKAPKGSVILTM 328


>UniRef50_B6VLL1 Cysteine synthase n=1 Tax=Photorhabdus asymbiotica subsp.
           asymbiotica ATCC 43949 RepID=B6VLL1_PHOAA
          Length = 348

 Score = 68.4 bits (166), Expect = 4e-10,   Method: Composition-based stats.
 Identities = 61/317 (19%), Positives = 111/317 (35%), Gaps = 62/317 (19%)

Query: 70  NTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE---IIAETGAGQHGVASALASALL 126
              ++LK E++   G+ K    +     A+  G+     ++ E  +G   +  A+A A+ 
Sbjct: 32  GVNIFLKMENINPSGSIKDRIAVAMLEKAEAQGELRPGMVVVEPSSGNTAIGLAMACAVK 91

Query: 127 GLKCRIYMGAKDVERQSPNVFRMRLMGAEVI---PVHSGSATLKDACNEALRDWSGSYET 183
           G +    +       +     ++R  GAE+I      +G+ T+K   +   ++   +Y  
Sbjct: 92  GYRFIAVLDRMVPAAK---RDKIRAFGAEIIFLPEFEAGTDTVKYRID-LTKEIIKAYPN 147

Query: 184 AHYMLGTAAGPHPYPTIVR--EFQRMIGEETKAQILEREGRLPDAVIAC--VGGGSNAIG 239
           A         P  +   +   E     G E             D + AC    G    + 
Sbjct: 148 AF-------SPMQFENQINPDEHYHSTGRELYETFG-------DNLTACFATAGSCGTLT 193

Query: 240 MFADFINETN--VGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEES 297
             + ++ E N  V + GVEP G  I  GE G  L  G                       
Sbjct: 194 GISRYLKEKNPWVRIYGVEPVGSVIFGGEPGKYLVQG----------------------- 230

Query: 298 YSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAH 357
               AGL F    P    L++      + ITD +A    + L   EGI+     + ++  
Sbjct: 231 ----AGLTFV---PSILDLSNIDIT--LKITDIDAFRMARKLARDEGILLGGTGACSVCA 281

Query: 358 ALKMMRENPDKEQLLVV 374
            L  + +    + ++V+
Sbjct: 282 VLDRLDDFKPGDNIVVI 298


>UniRef50_B9KDA6 Cysteine synthase n=2 Tax=Campylobacterales RepID=B9KDA6_CAMLR
          Length = 300

 Score = 68.4 bits (166), Expect = 4e-10,   Method: Composition-based stats.
 Identities = 69/332 (20%), Positives = 113/332 (34%), Gaps = 73/332 (21%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQV---LGQALLAKRMGKTEIIAETGAG 113
           T +   +         LY K E L    + K       + QAL   ++ +   I E  +G
Sbjct: 14  TPIISLKEFA----PNLYAKCEYLNPSHSIKDRAAVEMIKQALSEGKINQETTIIEATSG 69

Query: 114 QHGVASALASALLGLKCRIYMGAK-DVERQSPNVFRMRLMGAEVIPVH--SGSATLKDAC 170
             G+A A+  A L LK  I M     +ER+      M   GA++       G     D  
Sbjct: 70  NTGIALAMICASLKLKLIIAMPESMSIERRKM----MSFFGAKLELTQANKGMQGALDRA 125

Query: 171 NEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEET--KAQILEREGRLPDAVI 228
           NE L +                   P   +V +F+ +  +    K   LE    LPD  I
Sbjct: 126 NELLSEI------------------PNSFMVSQFENINNKNAHRKNTALEILKALPDLDI 167

Query: 229 ACVGGGSNAIGMFADF-----INETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMK 283
              G G+   G  +        +  NV +I +EP    + +    A  K           
Sbjct: 168 FLAGFGTG--GTISGVGEILKEHNPNVKIIALEPAASPLLSQNIAASHK----------- 214

Query: 284 APMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHE 343
              +Q                           LN     + V +++++A+     L  + 
Sbjct: 215 ---IQGIGANFIPK-----------------ILNQKIIDEIVCVSNEDAINTALELGKN- 253

Query: 344 GIIPALESSHALAHALKMMRENPDKEQLLVVN 375
           GI+  + S   +  A K+  ENP+K+ L ++N
Sbjct: 254 GIMAGISSGANVYMARKIALENPNKKVLTMLN 285


>UniRef50_C3MRI3 Threonine dehydratase n=12 Tax=Sulfolobaceae RepID=C3MRI3_SULIL
          Length = 405

 Score = 68.4 bits (166), Expect = 5e-10,   Method: Composition-based stats.
 Identities = 37/172 (21%), Positives = 58/172 (33%), Gaps = 23/172 (13%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T +      +  TN  +YLK E+L   G+ K      + L  K   K + +    AG H 
Sbjct: 24  TPIDYSTTFSRITNAKVYLKLENLQKTGSFKVRGAFNKLLSLKEEEKKKGVIAVSAGNHA 83

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD 176
              A A++ L ++  I M       +       R  GA+V+             +E+++ 
Sbjct: 84  QGVAYAASTLNIRSTIVMPETAPASKYLAT---RSYGADVVL-------YGKYLHESMKK 133

Query: 177 WSGSYETAHYMLGTAAGPHPYPTI-VREFQRMIGEETKAQILEREGRLPDAV 227
                +            HPY  + V   Q  IG E            PD V
Sbjct: 134 AEELIQNT-----GLIFVHPYGDLDVIVGQGTIGLEL-------YDVEPDYV 173


>UniRef50_C7LQS0 Cysteine synthase n=2 Tax=Desulfovibrionales RepID=C7LQS0_DESBD
          Length = 768

 Score = 68.4 bits (166), Expect = 5e-10,   Method: Composition-based stats.
 Identities = 70/324 (21%), Positives = 104/324 (32%), Gaps = 57/324 (17%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK---TEIIAETGAG 113
           T +     +       L  K E    GG+ K    L     A+  G+    + + E  +G
Sbjct: 13  TPVVYLNRVFPHPRIRLATKLEAQNVGGSIKDRVALAMIEAAEASGELTPDKTVIEATSG 72

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
             GV  A+  A+ G K  + M     E        MR  GAE+     G      A  EA
Sbjct: 73  NTGVGLAMVCAVKGYKLTLLMPDSASEE---RKRIMRAFGAELRLTP-GRLGTDGAIEEA 128

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
            R      E   Y+L         P  +       G E   Q    EGR    VI+    
Sbjct: 129 YR--LAREEPQTYVL---MDQFNNPASIAAHYMGTGREIIEQ---TEGRATHVVISLGTS 180

Query: 234 GSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDG 292
           G+ A+G+          + ++ VEP                     Y G K   ++    
Sbjct: 181 GT-AMGIAKRMKESAPGIQVVAVEP---------------------YAGHKIQGLKNMQE 218

Query: 293 QIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESS 352
                      LD                   + + D+EA    + L   EGI+  + + 
Sbjct: 219 SYPPGIYDKRALD-----------------RIIHVEDEEAFACARQLAREEGILSGMSAG 261

Query: 353 HALAHALKMMREN--PDKEQLLVV 374
            ALA AL++ RE     +E L+V 
Sbjct: 262 AALAGALRIARELDEAGEEGLIVF 285


>UniRef50_C2HF35 Cysteine synthase n=1 Tax=Finegoldia magna ATCC 53516
           RepID=C2HF35_PEPMA
          Length = 305

 Score = 68.0 bits (165), Expect = 5e-10,   Method: Composition-based stats.
 Identities = 64/320 (20%), Positives = 112/320 (35%), Gaps = 56/320 (17%)

Query: 60  TKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE---IIAETGAGQHG 116
           T+   +    N  +Y+K E     G+ K    L     A   G  +    I E  +G  G
Sbjct: 18  TRLVRLKNIGNGNIYVKVEKENATGSIKDRAALEMIRGAIDDGSLKPGMKIVEPTSGNTG 77

Query: 117 VASALASALLGLKCRIYMGAK-DVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
           +A A+    LG    I M     +ER       M+  GA +I    G   ++ A ++A  
Sbjct: 78  IAIAMIGQNLGYDVTIVMPESMSIER----RKLMQAYGATIILT--GEGGMQTAVDKAKE 131

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
             +      ++ML   A P+         ++  G E  +++ E +G +            
Sbjct: 132 LEATGE---YFMLNQFANPYN----TLAHEKYTGPEIYSELPEVKGFIAGVGTG------ 178

Query: 236 NAIGMFADFINE--TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQ 293
             +     F+ E   NV +  +EP        E  A L  G+ G   G K   +Q     
Sbjct: 179 GTVTGVGHFLKEKNENVAVWAIEP--------EESALLSTGKAG---GHK---IQGIGAN 224

Query: 294 IEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSH 353
                     LD                 + +++  D+AL+  + L   EG++  + S  
Sbjct: 225 FVPEILDRDMLD-----------------EVITVKGDDALDMARRLAKEEGLLVGISSGA 267

Query: 354 ALAHALKMMRENPDKEQLLV 373
            +  ALKM+ +       ++
Sbjct: 268 NVFGALKMLEKVDGPIVTVL 287


Searching..................................................done


Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_A6VPD9 Tryptophan synthase beta chain n=265 Tax=cellula...   462   e-129
UniRef50_B0TP63 Tryptophan synthase beta chain n=124 Tax=cellula...   436   e-121
UniRef50_D2LTS0 Tryptophan synthase, beta subunit n=1 Tax=Bacill...   433   e-120
UniRef50_P00931 Tryptophan synthase n=45 Tax=Eukaryota RepID=TRP...   429   e-119
UniRef50_P25269 Tryptophan synthase beta chain 2, chloroplastic ...   428   e-118
UniRef50_Q7VR00 Tryptophan synthase beta chain n=5 Tax=Bacteria ...   428   e-118
UniRef50_C9KJ78 Tryptophan synthase, beta subunit n=1 Tax=Mitsuo...   426   e-118
UniRef50_B1XY48 Tryptophan synthase beta chain n=287 Tax=cellula...   423   e-117
UniRef50_B7FQI2 Predicted protein n=1 Tax=Phaeodactylum tricornu...   414   e-114
UniRef50_A8Z5Y3 Putative tryptophan synthase, beta subunit (TrpB...   414   e-114
UniRef50_D0JB95 Bifunctional phosphoribosylanthranilate isomeras...   412   e-113
UniRef50_A1KSW2 Tryptophan synthase beta chain n=49 Tax=Bacteria...   412   e-113
UniRef50_C5V964 Tryptophan synthase, beta subunit n=2 Tax=Coryne...   409   e-113
UniRef50_A5UMB9 Tryptophan synthase, beta subunit, TrpB n=5 Tax=...   407   e-112
UniRef50_D1HPU5 Whole genome shotgun sequence of line PN40024, s...   405   e-111
UniRef50_Q2S700 Tryptophan synthase, beta subunit n=6 Tax=Bacter...   397   e-109
UniRef50_Q7VGA7 Tryptophan synthase beta chain n=4 Tax=Proteobac...   392   e-107
UniRef50_B2TM49 Tryptophan synthase beta chain n=40 Tax=cellular...   392   e-107
UniRef50_D2VKV7 Predicted protein n=1 Tax=Naegleria gruberi RepI...   383   e-105
UniRef50_B2KCI5 Tryptophan synthase beta chain n=2 Tax=Bacteria ...   383   e-105
UniRef50_Q822W9 Tryptophan synthase beta chain 1 n=8 Tax=Bacteri...   382   e-104
UniRef50_B0ZSJ6 Tryptophan synthase beta subunit n=3 Tax=rosids ...   380   e-104
UniRef50_C1FGK1 Predicted protein n=14 Tax=cellular organisms Re...   373   e-102
UniRef50_C0NSJ2 Bifunctional tryptophan synthase TRPB n=1 Tax=Aj...   373   e-102
UniRef50_Q0RGR3 Tryptophan synthase, beta protein n=2 Tax=Actino...   367   e-100
UniRef50_B0R332 Tryptophan synthase beta chain n=8 Tax=cellular ...   364   3e-99
UniRef50_B7G4U3 Tryptophan synthase, beta chain n=3 Tax=cellular...   353   5e-96
UniRef50_B8MZR1 Trytophan synthase alpha subunit, putative n=2 T...   342   2e-92
UniRef50_C0QZH7 Tryptophan synthase beta subunit n=4 Tax=Bacteri...   340   4e-92
UniRef50_A1DP73 Tryptophan synthase n=4 Tax=Trichocomaceae RepID...   324   2e-87
UniRef50_Q1V1Q0 Tryptophan synthase beta chain 1 n=6 Tax=root Re...   323   7e-87
UniRef50_B6HPP8 Pc22g00910 protein n=1 Tax=Penicillium chrysogen...   319   1e-85
UniRef50_C8VGH6 Putative uncharacterized protein n=2 Tax=Emerice...   308   2e-82
UniRef50_Q9WZ09 Tryptophan synthase beta chain 2 n=6 Tax=Bacteri...   280   6e-74
UniRef50_B6YSU5 Tryptophan synthase beta chain n=232 Tax=cellula...   280   6e-74
UniRef50_D2L2T8 Pyridoxal-phosphate dependent TrpB-like enzyme n...   272   1e-71
UniRef50_A8F8F7 Tryptophan synthase beta chain n=12 Tax=cellular...   271   4e-71
UniRef50_Q9Y8T5 Tryptophan synthase beta chain 1 n=10 Tax=Thermo...   266   8e-70
UniRef50_C7N0P7 Pyridoxal-phosphate dependent TrpB-like enzyme n...   255   2e-66
UniRef50_Q13AA2 Tryptophan synthase, beta chain-like n=7 Tax=Bac...   253   8e-66
UniRef50_B1KQQ7 Pyridoxal-5'-phosphate-dependent protein beta su...   250   9e-65
UniRef50_C7GZ56 Tryptophan synthase beta chain 2 n=3 Tax=Bacteri...   247   7e-64
UniRef50_Q970N1 Tryptophan synthase beta chain 2 n=16 Tax=Archae...   246   2e-63
UniRef50_Q58860 Probable threonine synthase n=38 Tax=Archaea Rep...   235   2e-60
UniRef50_C2BGX3 Threonine ammonia-lyase n=3 Tax=Anaerococcus Rep...   234   4e-60
UniRef50_C7DG26 Pyridoxal-phosphate dependent TrpB-like enzyme n...   234   5e-60
UniRef50_B6A2K1 Pyridoxal-5'-phosphate-dependent protein beta su...   230   9e-59
UniRef50_B6YXA7 Hypothetical threonine synthase (TS) n=1 Tax=The...   227   5e-58
UniRef50_Q54HH2 Probable serine racemase n=1 Tax=Dictyostelium d...   226   1e-57
UniRef50_B7G9B5 L-threonine ammonia-lyase n=3 Tax=cellular organ...   224   7e-57
UniRef50_Q2SSZ6 Threonine dehydratase n=3 Tax=Mycoplasma mycoide...   223   8e-57
UniRef50_Q3M5I1 Cystathionine beta-synthase n=5 Tax=cellular org...   223   1e-56
UniRef50_C4Z926 Threonine dehydratase n=58 Tax=Bacteria RepID=C4...   222   1e-56
UniRef50_D0N3C1 Cysteine synthase, putative n=1 Tax=Phytophthora...   222   2e-56
UniRef50_C4V2P7 Threonine ammonia-lyase n=1 Tax=Selenomonas flue...   222   2e-56
UniRef50_B2KE33 Threonine synthase n=1 Tax=Elusimicrobium minutu...   221   4e-56
UniRef50_Q0W7Y3 Threonine synthase n=2 Tax=Euryarchaeota RepID=Q...   219   1e-55
UniRef50_D1AJT1 Threonine dehydratase n=8 Tax=Bacteria RepID=D1A...   219   1e-55
UniRef50_Q1IPW5 Pyridoxal-5'-phosphate-dependent enzyme, beta su...   218   2e-55
UniRef50_Q5HMF5 Threonine dehydratase biosynthetic n=12 Tax=Bact...   218   4e-55
UniRef50_A8M857 Pyridoxal-5'-phosphate-dependent protein beta su...   217   7e-55
UniRef50_Q1QC42 Pyridoxal-5'-phosphate-dependent enzyme, beta su...   216   9e-55
UniRef50_B0R722 Threonine ammonia-lyase n=12 Tax=cellular organi...   215   3e-54
UniRef50_B5YF95 Threonine dehydratase n=2 Tax=Dictyoglomus RepID...   215   3e-54
UniRef50_A8F881 Pyridoxal-5'-phosphate-dependent protein beta su...   214   7e-54
UniRef50_Q1I705 Threonine synthase n=2 Tax=Pseudomonas RepID=Q1I...   213   7e-54
UniRef50_C6A3C7 Threonine synthase n=6 Tax=cellular organisms Re...   213   8e-54
UniRef50_C5D2E8 Threonine dehydratase n=9 Tax=cellular organisms...   213   8e-54
UniRef50_Q97CB2 Threonine deaminase n=4 Tax=Thermoplasmatales Re...   213   1e-53
UniRef50_A3DKP7 L-threonine synthase n=2 Tax=Desulfurococcaceae ...   211   3e-53
UniRef50_D1C5Q2 Cystathionine beta-synthase n=30 Tax=Bacteria Re...   211   3e-53
UniRef50_B6JWQ1 Threonine dehydratase n=1 Tax=Schizosaccharomyce...   211   3e-53
UniRef50_D2S0A7 Threonine synthase n=6 Tax=Halobacteriaceae RepI...   211   4e-53
UniRef50_C6A508 Probable threonine synthase n=1 Tax=Thermococcus...   211   4e-53
UniRef50_O59701 Cysteine synthase 1 n=133 Tax=cellular organisms...   209   1e-52
UniRef50_C0WC35 Threonine dehydratase n=1 Tax=Acidaminococcus sp...   209   2e-52
UniRef50_D1Y7Y8 Threonine synthase n=1 Tax=Pyramidobacter piscol...   209   2e-52
UniRef50_C1PE10 Threonine dehydratase n=2 Tax=Bacillaceae RepID=...   208   3e-52
UniRef50_A8MDC1 Threonine dehydratase n=9 Tax=cellular organisms...   208   3e-52
UniRef50_A5CWZ8 Threonine dehydratase n=1 Tax=Candidatus Vesicom...   208   3e-52
UniRef50_A5N599 IlvE1 n=23 Tax=Bacteria RepID=A5N599_CLOK5            207   4e-52
UniRef50_C5CHS7 Threonine synthase n=2 Tax=Thermotogaceae RepID=...   207   8e-52
UniRef50_A9BIT3 Threonine synthase n=4 Tax=Bacteria RepID=A9BIT3...   207   8e-52
UniRef50_D1NGU1 DNA (Cytosine-5-)-methyltransferase (Fragment) n...   206   9e-52
UniRef50_A0LFH6 Cysteine synthases n=15 Tax=cellular organisms R...   206   1e-51
UniRef50_Q3A093 L-threonine ammonia-lyase n=9 Tax=Desulfuromonad...   205   2e-51
UniRef50_C1ZHQ7 Threonine dehydratase n=4 Tax=Bacteria RepID=C1Z...   205   2e-51
UniRef50_C6A2V6 Threonine dehydratase n=1 Tax=Thermococcus sibir...   205   3e-51
UniRef50_A7I331 Threonine dehydratase n=54 Tax=Bacteria RepID=A7...   204   4e-51
UniRef50_Q6MP14 Threonine ammonia-lyase n=1 Tax=Bdellovibrio bac...   203   1e-50
UniRef50_Q4LEC5 Threonine synthase n=1 Tax=uncultured crenarchae...   202   1e-50
UniRef50_O94634 Threonine dehydratase, mitochondrial n=5 Tax=cel...   202   2e-50
UniRef50_B5FEL5 Threonine synthase n=2 Tax=Vibrio fischeri RepID...   202   2e-50
UniRef50_P50867 Cysteine synthase n=103 Tax=cellular organisms R...   202   2e-50
UniRef50_B0VGY7 Putative threonine synthase n=1 Tax=Candidatus C...   201   4e-50
UniRef50_Q2PGG3 Serine racemase n=18 Tax=cellular organisms RepI...   201   4e-50
UniRef50_C1TP96 Threonine synthase n=1 Tax=Dethiosulfovibrio pep...   201   4e-50
UniRef50_B8P126 Predicted protein n=6 Tax=cellular organisms Rep...   200   5e-50
UniRef50_C6Q2L0 Threonine dehydratase n=1 Tax=Clostridium carbox...   200   5e-50
UniRef50_C1AEM2 Cystathionine beta-synthase n=1 Tax=Gemmatimonas...   200   6e-50
UniRef50_D2S288 Threonine dehydratase n=2 Tax=Haloterrigena turk...   200   1e-49
UniRef50_B5E900 Cysteine synthase n=1 Tax=Geobacter bemidjiensis...   199   1e-49
UniRef50_A8MAW5 Threonine synthase n=1 Tax=Caldivirga maquilinge...   199   1e-49
UniRef50_B9Z0N9 Pyridoxal-5'-phosphate-dependent protein beta su...   199   2e-49
UniRef50_C7RHX8 Threonine dehydratase n=26 Tax=Bacteria RepID=C7...   199   2e-49
UniRef50_Q64CL8 Threonine synthase n=1 Tax=uncultured archaeon G...   199   2e-49
UniRef50_B0TBV3 Threonine synthase n=1 Tax=Heliobacterium modest...   199   2e-49
UniRef50_A5V1I5 L-threonine ammonia-lyase n=2 Tax=Roseiflexus Re...   199   2e-49
UniRef50_A3DKY8 Transcriptional regulator n=1 Tax=Staphylothermu...   198   2e-49
UniRef50_A5F498 Threonine dehydratase n=35 Tax=Bacteria RepID=A5...   198   3e-49
UniRef50_C6HUM2 Cysteine synthase n=1 Tax=Leptospirillum ferrodi...   198   3e-49
UniRef50_C5A2G0 Threonine synthase (ThrC) n=1 Tax=Thermococcus g...   198   4e-49
UniRef50_Q01PK6 Pyridoxal-5'-phosphate-dependent enzyme, beta su...   198   4e-49
UniRef50_Q03HP8 L-threonine ammonia-lyase n=18 Tax=Bacteria RepI...   197   5e-49
UniRef50_D2Q7L3 TdcB Threonine dehydratase n=10 Tax=Bifidobacter...   197   8e-49
UniRef50_B0T581 Cysteine synthase n=51 Tax=Bacteria RepID=B0T581...   196   1e-48
UniRef50_A2ETD5 Threonine synthase family protein n=1 Tax=Tricho...   196   1e-48
UniRef50_A9A5N3 Threonine dehydratase n=3 Tax=Thaumarchaeota Rep...   195   2e-48
UniRef50_D2RYT3 Threonine dehydratase n=1 Tax=Haloterrigena turk...   195   2e-48
UniRef50_C9M5D2 Threonine synthase n=1 Tax=Jonquetella anthropi ...   195   2e-48
UniRef50_C6A468 Cysteine synthase n=1 Tax=Thermococcus sibiricus...   195   3e-48
UniRef50_C3BFH3 Threonine dehydratase catabolic n=6 Tax=Bacillus...   195   3e-48
UniRef50_B6YXV5 Threonine synthase n=2 Tax=Thermococcus RepID=B6...   194   4e-48
UniRef50_P00927 Threonine dehydratase, mitochondrial n=48 Tax=ce...   194   4e-48
UniRef50_B3T1L2 Putative Pyridoxal-phosphate dependent enzyme n=...   194   4e-48
UniRef50_A1A3R8 Catabolic threonine dehydratase n=8 Tax=Bifidoba...   194   5e-48
UniRef50_D1C1V4 Threonine synthase n=3 Tax=Bacteria RepID=D1C1V4...   194   5e-48
UniRef50_Q9K7E3 Threonine synthase n=82 Tax=cellular organisms R...   194   6e-48
UniRef50_C2KWC0 Threonine ammonia-lyase n=1 Tax=Oribacterium sin...   194   7e-48
UniRef50_D1CDZ3 Pyridoxal-5'-phosphate-dependent protein beta su...   193   8e-48
UniRef50_D1TEY8 Pyridoxal-5'-phosphate-dependent protein beta su...   193   8e-48
UniRef50_UPI00006A66AE PREDICTED: similar to GH19036 n=1 Tax=Cio...   193   9e-48
UniRef50_Q07RL7 L-threonine ammonia-lyase n=40 Tax=Bacteria RepI...   192   2e-47
UniRef50_A3DLX2 L-threonine ammonia-lyase n=2 Tax=Thermoprotei R...   192   2e-47
UniRef50_C9RSS0 Threonine synthase n=13 Tax=Bacteria RepID=C9RSS...   191   3e-47
UniRef50_Q6C6D8 YALI0E10307p n=1 Tax=Yarrowia lipolytica RepID=Q...   191   3e-47
UniRef50_O34476 Probable cysteine synthase n=7 Tax=Bacteria RepI...   191   3e-47
UniRef50_A3DLF6 Cysteine synthase n=2 Tax=Desulfurococcaceae Rep...   191   3e-47
UniRef50_Q9Y9K2 Threonine synthase n=1 Tax=Aeropyrum pernix RepI...   191   4e-47
UniRef50_A9B771 Cystathionine beta-synthase n=12 Tax=Bacteria Re...   191   4e-47
UniRef50_P74193 Threonine synthase n=364 Tax=cellular organisms ...   190   6e-47
UniRef50_Q5WD43 Threonine synthase n=4 Tax=Bacillus RepID=Q5WD43...   190   6e-47
UniRef50_UPI0000519DB2 PREDICTED: similar to CG8129-PB, isoform ...   190   6e-47
UniRef50_B9JX06 Threonine dehydratase n=16 Tax=Alphaproteobacter...   190   6e-47
UniRef50_Q9CKJ2 Threonine dehydratase biosynthetic n=145 Tax=Bac...   190   7e-47
UniRef50_C1N5N0 Cysteine synthase n=1 Tax=Micromonas pusilla CCM...   190   8e-47
UniRef50_B9J9P9 Threonine dehydratase protein n=49 Tax=Alphaprot...   190   1e-46
UniRef50_C4LUI9 Threonine dehydratase, putative n=4 Tax=Entamoeb...   190   1e-46
UniRef50_D0LAQ5 Threonine dehydratase n=6 Tax=Actinomycetales Re...   189   1e-46
UniRef50_D0NAZ0 Serine racemase, putative n=1 Tax=Phytophthora i...   189   1e-46
UniRef50_A5VDD7 Cysteine synthase n=28 Tax=cellular organisms Re...   189   2e-46
UniRef50_C9N4U4 Pyridoxal-5'-phosphate-dependent protein beta su...   189   2e-46
UniRef50_Q2YY67 Threonine dehydratase catabolic n=139 Tax=Bacter...   189   2e-46
UniRef50_C5LC28 Cysteine synthase n=2 Tax=Perkinsus marinus ATCC...   189   2e-46
UniRef50_Q2S090 Threonine dehydratase n=6 Tax=cellular organisms...   189   2e-46
UniRef50_D1IAP7 Whole genome shotgun sequence of line PN40024, s...   188   3e-46
UniRef50_A0LG82 L-threonine ammonia-lyase n=2 Tax=cellular organ...   188   4e-46
UniRef50_B5H9V7 Threonine synthase n=4 Tax=Streptomyces RepID=B5...   187   4e-46
UniRef50_A6GXZ8 Cysteine synthase/cystathionine beta-synthase fa...   187   5e-46
UniRef50_Q02145 Threonine dehydratase biosynthetic n=83 Tax=Bact...   187   5e-46
UniRef50_B4AUD2 Threonine synthase, putative n=23 Tax=Francisell...   187   6e-46
UniRef50_A4RXR0 Predicted protein n=16 Tax=cellular organisms Re...   187   7e-46
UniRef50_A2FH13 Pyridoxal-phosphate dependent enzyme family prot...   187   8e-46
UniRef50_C1SG53 Threonine dehydratase, medium form n=1 Tax=Denit...   186   9e-46
UniRef50_A5EK00 L-threonine synthase n=11 Tax=Bacteria RepID=A5E...   186   1e-45
UniRef50_B0AA90 Cysteine synthase n=4 Tax=Firmicutes RepID=B0AA9...   186   1e-45
UniRef50_Q15NS2 Pyridoxal-5'-phosphate-dependent enzyme, beta su...   186   1e-45
UniRef50_C1E0J2 Predicted protein n=1 Tax=Micromonas sp. RCC299 ...   185   2e-45
UniRef50_A0D3F4 Chromosome undetermined scaffold_36, whole genom...   185   2e-45
UniRef50_Q5K9M8 Threonine ammonia-lyase, putative n=6 Tax=cellul...   185   3e-45
UniRef50_UPI00006CA830 Pyridoxal-phosphate dependent enzyme fami...   185   3e-45
UniRef50_A6GJR2 Cysteine synthase n=1 Tax=Plesiocystis pacifica ...   185   3e-45
UniRef50_B0TB97 Threonine dehydratase n=13 Tax=Firmicutes RepID=...   185   3e-45
UniRef50_A9V280 Predicted protein n=4 Tax=cellular organisms Rep...   185   3e-45
UniRef50_Q83FN5 Threonine deaminase n=2 Tax=Tropheryma whipplei ...   184   4e-45
UniRef50_A2BKW1 Threonine synthase n=1 Tax=Hyperthermus butylicu...   184   5e-45
UniRef50_Q3ADX2 Cysteine synthase n=10 Tax=cellular organisms Re...   184   5e-45
UniRef50_D2VDG8 Predicted protein n=1 Tax=Naegleria gruberi RepI...   184   5e-45
UniRef50_Q1ITV7 L-threonine ammonia-lyase n=7 Tax=Bacteria RepID...   184   6e-45
UniRef50_P53607 Threonine dehydratase biosynthetic n=494 Tax=cel...   184   7e-45
UniRef50_UPI000180BB5B PREDICTED: similar to Serine racemase n=2...   184   7e-45
UniRef50_D1CDN5 Threonine synthase n=1 Tax=Thermobaculum terrenu...   183   8e-45
UniRef50_B3EGT7 Cysteine synthase A n=8 Tax=Bacteria RepID=B3EGT...   183   8e-45
UniRef50_Q9F7T0 Predicted threonine dehydratase n=1 Tax=uncultur...   183   1e-44
UniRef50_C6XK52 Pyridoxal-5'-phosphate-dependent protein beta su...   183   1e-44
UniRef50_A2FRC0 Threonine dehydratase family protein n=1 Tax=Tri...   183   1e-44
UniRef50_C5DI11 Cysteine synthase n=19 Tax=Saccharomyceta RepID=...   183   1e-44
UniRef50_B2UPE5 Pyridoxal-5'-phosphate-dependent protein beta su...   182   1e-44
UniRef50_A6F8H1 Threonine dehydratase n=1 Tax=Moritella sp. PE36...   182   2e-44
UniRef50_Q22B57 Threonine dehydratase family protein n=2 Tax=cel...   182   2e-44
UniRef50_C6C043 Cysteine synthase n=5 Tax=Bacteria RepID=C6C043_...   182   2e-44
UniRef50_UPI0001978075 cysteine synthase n=1 Tax=Helicobacter ci...   182   2e-44
UniRef50_D1Y7A1 Pyridoxal-5'-phosphate-dependent protein beta su...   182   2e-44
UniRef50_Q3M387 L-threonine synthase n=107 Tax=cellular organism...   182   2e-44
UniRef50_P71128 Cysteine synthase B n=12 Tax=Campylobacter RepID...   182   3e-44
UniRef50_UPI000180C4E2 PREDICTED: similar to Serine racemase n=1...   182   3e-44
UniRef50_Q88I11 Threonine dehydratase family protein n=43 Tax=ce...   181   4e-44
UniRef50_A6VNW0 Pyridoxal-5'-phosphate-dependent protein beta su...   181   4e-44
UniRef50_D2B021 Pyridoxal-5'-phosphate-dependent protein beta su...   181   4e-44
UniRef50_Q7MYV0 Cysteine synthase n=1 Tax=Photorhabdus luminesce...   181   5e-44
UniRef50_D1X751 Pyridoxal-5'-phosphate-dependent protein beta su...   180   5e-44
UniRef50_Q2YUE8 Threonine dehydratase biosynthetic n=181 Tax=Bac...   180   5e-44
UniRef50_D0L0K6 Threonine synthase n=20 Tax=Gammaproteobacteria ...   180   5e-44
UniRef50_C3WXN8 Cysteine synthase n=12 Tax=Fusobacterium RepID=C...   180   6e-44
UniRef50_A7RTQ8 Predicted protein n=2 Tax=Nematostella vectensis...   180   6e-44
UniRef50_C5CDJ9 Pyridoxal-5'-phosphate-dependent protein beta su...   180   6e-44
UniRef50_D1CAE1 Pyridoxal-5'-phosphate-dependent protein beta su...   180   6e-44
UniRef50_C5C994 L-threonine ammonia-lyase n=59 Tax=Actinobacteri...   180   7e-44
UniRef50_B6VLL1 Cysteine synthase n=1 Tax=Photorhabdus asymbioti...   180   8e-44
UniRef50_Q9YCN5 Cystathionine beta-synthase n=1 Tax=Aeropyrum pe...   180   8e-44
UniRef50_A4JPA1 L-threonine ammonia-lyase n=4 Tax=cellular organ...   180   1e-43
UniRef50_Q2RHT1 Cysteine synthase n=6 Tax=Bacteria RepID=Q2RHT1_...   180   1e-43
UniRef50_A2QU10 Function: catalyzes L-serine to D-serine racemiz...   179   1e-43
UniRef50_UPI000180D414 PREDICTED: similar to K01C8.1 n=1 Tax=Cio...   179   1e-43
UniRef50_A8MA47 Pyridoxal-5'-phosphate-dependent protein beta su...   179   1e-43
UniRef50_A1WTA6 L-threonine synthase n=12 Tax=Bacteria RepID=A1W...   179   1e-43
UniRef50_Q5WLV3 Cysteine synthase n=48 Tax=Bacteria RepID=Q5WLV3...   179   2e-43
UniRef50_B8J2I1 Cysteine synthase n=1 Tax=Desulfovibrio desulfur...   179   2e-43
UniRef50_A6RLV9 Putative uncharacterized protein n=3 Tax=Sordari...   179   2e-43
UniRef50_Q0C326 Pyridoxal-phosphate-dependent enzyme n=8 Tax=Bac...   179   2e-43
UniRef50_C9KLW2 Threonine synthase n=2 Tax=Veillonellaceae RepID...   179   2e-43
UniRef50_A9VB30 Predicted protein n=1 Tax=Monosiga brevicollis R...   178   3e-43
UniRef50_A8ABB1 L-threonine synthase n=45 Tax=cellular organisms...   178   3e-43
UniRef50_Q5KGT7 Serine family amino acid catabolism-related prot...   178   3e-43
UniRef50_A3ERN7 Cysteine synthase n=2 Tax=Leptospirillum sp. Gro...   178   3e-43
UniRef50_Q8YXP3 Cysteine synthase n=2 Tax=Nostoc sp. PCC 7120 Re...   178   3e-43
UniRef50_A7IFG1 Pyridoxal-5'-phosphate-dependent protein beta su...   178   3e-43
UniRef50_Q10725 Phenylserine dehydratase n=62 Tax=Proteobacteria...   178   3e-43
UniRef50_Q59447 Cysteine synthase n=20 Tax=Bacteria RepID=CYSK_F...   178   4e-43
UniRef50_Q9X7F1 Probable threonine dehydratase biosynthetic n=24...   177   5e-43

Sequences not found previously or not previously below threshold:

UniRef50_C3YDM6 Putative uncharacterized protein n=1 Tax=Branchi...   198   4e-49
UniRef50_Q9GZT4 Serine racemase n=27 Tax=Deuterostomia RepID=SRR...   198   4e-49
UniRef50_P35520 Cystathionine beta-synthase n=65 Tax=cellular or...   196   1e-48
UniRef50_Q2S3I1 Cystathionine beta-synthase n=30 Tax=cellular or...   194   4e-48
UniRef50_B6JZ56 Cysteine synthase n=1 Tax=Schizosaccharomyces ja...   194   7e-48
UniRef50_B9Z5C8 Cysteine synthase n=1 Tax=Lutiella nitroferrum 2...   192   1e-47
UniRef50_C1EEG6 Predicted protein n=1 Tax=Micromonas sp. RCC299 ...   191   4e-47
UniRef50_P87131 Cysteine synthase 2 n=16 Tax=Ascomycota RepID=CY...   189   1e-46
UniRef50_D0N4G9 Cysteine synthase n=2 Tax=Phytophthora infestans...   188   4e-46
UniRef50_C3XUX1 Putative uncharacterized protein n=3 Tax=Branchi...   184   5e-45
UniRef50_C4PYD1 Cysteine synthase, putative n=2 Tax=Schistosoma ...   184   6e-45
UniRef50_B5IBS9 Threonine synthase n=2 Tax=Aciduliprofundum boon...   183   9e-45
UniRef50_C3DBY4 Cystathionine beta-synthase n=2 Tax=Bacillus thu...   183   1e-44
UniRef50_Q3A4C8 Cysteine synthase n=3 Tax=Bacteria RepID=Q3A4C8_...   183   1e-44
UniRef50_D2VUI3 Predicted protein n=1 Tax=Naegleria gruberi RepI...   182   2e-44
UniRef50_C5DGC1 KLTH0D04092p n=2 Tax=Saccharomycetales RepID=C5D...   182   3e-44
UniRef50_Q54CN7 Cysteine synthase n=1 Tax=Dictyostelium discoide...   181   4e-44
UniRef50_C0D8B2 Putative uncharacterized protein n=1 Tax=Clostri...   181   5e-44
UniRef50_A9VDJ3 Cysteine synthase n=1 Tax=Monosiga brevicollis R...   178   3e-43
UniRef50_Q1D4S7 Cysteine synthase n=3 Tax=Deltaproteobacteria Re...   177   4e-43

>UniRef50_A6VPD9 Tryptophan synthase beta chain n=265 Tax=cellular organisms
           RepID=TRPB_ACTSZ
          Length = 398

 Score =  462 bits (1190), Expect = e-129,   Method: Composition-based stats.
 Identities = 321/395 (81%), Positives = 355/395 (89%)

Query: 3   TLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKC 62
           T+LNPYFGEFGGMYVP+IL+P L+QLE+AFV A+ DP+FQ +F DLLKNYAGRPTALT C
Sbjct: 4   TILNPYFGEFGGMYVPEILVPVLQQLEKAFVEARNDPDFQQEFQDLLKNYAGRPTALTLC 63

Query: 63  QNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALA 122
           +N+T GT T LYLKREDLLHGGAHKTNQVLGQ LLAKRMGKT IIAETGAGQHGVA+ALA
Sbjct: 64  RNLTKGTKTKLYLKREDLLHGGAHKTNQVLGQILLAKRMGKTRIIAETGAGQHGVATALA 123

Query: 123 SALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYE 182
            A+L + CR+YMG+KDVERQSPNVFRMRLMG EV+PV  GS +LKDAC EA+RDWS +YE
Sbjct: 124 CAMLDMPCRVYMGSKDVERQSPNVFRMRLMGTEVVPVEKGSCSLKDACCEAMRDWSANYE 183

Query: 183 TAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFA 242
             HY+LGTAAGPHP+PTIVREFQ+MIGEETK QILE+EG LPDAVIA VGGGSNAIGMF 
Sbjct: 184 NTHYLLGTAAGPHPFPTIVREFQKMIGEETKRQILEKEGCLPDAVIAAVGGGSNAIGMFT 243

Query: 243 DFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISA 302
           DFI+ETNV LIGVEP G GIETGEHGAPLKHG+ GIYFGMK+P+MQTEDGQIEESYSISA
Sbjct: 244 DFIDETNVRLIGVEPAGKGIETGEHGAPLKHGKTGIYFGMKSPIMQTEDGQIEESYSISA 303

Query: 303 GLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMM 362
           GLDFPSVGPQHAYLNS GRA+Y SITDDEAL AFK L  HEGIIPALESSHALA ALKM+
Sbjct: 304 GLDFPSVGPQHAYLNSIGRAEYPSITDDEALAAFKELAKHEGIIPALESSHALAQALKMI 363

Query: 363 RENPDKEQLLVVNLSGRGDKDIFTVHDILKARGEI 397
           + NP+KEQLLVVNLSGRGDKDIFTV  IL+A+GE+
Sbjct: 364 KSNPEKEQLLVVNLSGRGDKDIFTVDKILRAKGEL 398


>UniRef50_B0TP63 Tryptophan synthase beta chain n=124 Tax=cellular organisms
           RepID=TRPB_SHEHH
          Length = 419

 Score =  436 bits (1122), Expect = e-121,   Method: Composition-based stats.
 Identities = 307/393 (78%), Positives = 342/393 (87%), Gaps = 1/393 (0%)

Query: 3   TLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKC 62
           + LNPYFGE+GGMYVPQILMPAL+QLE AF+ AQ+D  FQ +F DLLKNYAGRPTALT  
Sbjct: 2   SKLNPYFGEYGGMYVPQILMPALKQLETAFIEAQEDEAFQEEFTDLLKNYAGRPTALTLT 61

Query: 63  QNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALA 122
           +N++      +YLKREDLLHGGAHKTNQVLGQALLAKRMGK EIIAETGAGQHGVA+ALA
Sbjct: 62  RNLSPNPLAKIYLKREDLLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVATALA 121

Query: 123 SALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYE 182
            ALLGLKCR+YMGAKDVERQSPNVFRM+LMGAEVIPV SGSATLKDACNEA+RDWSG Y+
Sbjct: 122 CALLGLKCRVYMGAKDVERQSPNVFRMKLMGAEVIPVTSGSATLKDACNEAMRDWSGCYD 181

Query: 183 TAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFA 242
            AHY+LGTAAGPHPYPTIVREFQRMIG ETK QILEREGRLPDAVIACVGGGSNAIGMFA
Sbjct: 182 KAHYLLGTAAGPHPYPTIVREFQRMIGAETKRQILEREGRLPDAVIACVGGGSNAIGMFA 241

Query: 243 DFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISA 302
           DFI+E  V LIGVEP G GI+T  HGAPL HG+ GI+FGMKAP+MQ  +GQ+EESYS+SA
Sbjct: 242 DFIDEPEVALIGVEPAGKGIDTPMHGAPLHHGKTGIFFGMKAPLMQDSEGQVEESYSVSA 301

Query: 303 GLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMM 362
           GLDFPSVGPQHA+L + GRA Y S TDDEALE F+ L   EGIIPALES+HA+A+A+K+ 
Sbjct: 302 GLDFPSVGPQHAHLAAIGRATYESATDDEALETFQLLARCEGIIPALESAHAIAYAVKLA 361

Query: 363 RENPDKEQLLVVNLSGRGDKDIFTVHDILKARG 395
           +E   KE LLVVNLSGRGDKDIFTV DIL+ + 
Sbjct: 362 KE-ATKETLLVVNLSGRGDKDIFTVADILEQQK 393


>UniRef50_D2LTS0 Tryptophan synthase, beta subunit n=1 Tax=Bacillus cellulosilyticus
           DSM 2522 RepID=D2LTS0_BACS4
          Length = 611

 Score =  433 bits (1114), Expect = e-120,   Method: Composition-based stats.
 Identities = 211/391 (53%), Positives = 270/391 (69%), Gaps = 2/391 (0%)

Query: 7   PYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNIT 66
             FG+FGG YVP+ LM AL QLE AF  A +D  F A+ ++  + Y+GRPT LT  + ++
Sbjct: 221 GRFGDFGGRYVPETLMYALEQLESAFDEAVQDEHFFAELHNEWEKYSGRPTPLTVAERLS 280

Query: 67  AGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASAL 125
                 ++YLKREDL H GAHK N  + QA+LAKRMGK +IIAETGAGQHGVA+A  +A 
Sbjct: 281 KTLGGASIYLKREDLNHTGAHKINNAIAQAILAKRMGKQQIIAETGAGQHGVAAATVAAR 340

Query: 126 LGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAH 185
            GL C+++MG +D++RQ  NVFRM+L+GAEVI V SG  TLKDA NEA+R W        
Sbjct: 341 FGLTCKVFMGEEDMKRQELNVFRMKLLGAEVIKVTSGGKTLKDATNEAIRHWVSHVNDTF 400

Query: 186 YMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFI 245
           Y++G+A GPHPYP +VREFQ +IG E++ Q L   G LPD VIACVGGGSNAIGMF  FI
Sbjct: 401 YLIGSAVGPHPYPKMVREFQSVIGRESRRQFLTETGALPDEVIACVGGGSNAIGMFYPFI 460

Query: 246 NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLD 305
           N+  V L GVE  G G++T EH A L  G  G+  G  + ++Q + G I E YSISAGLD
Sbjct: 461 NDEQVVLTGVEAAGKGVDTEEHAATLTKGVKGVLHGSLSYLLQDDFGNITEPYSISAGLD 520

Query: 306 FPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMREN 365
           +P +GP+HAYL   GR  Y SITD EA+EA +TLC  EGI+PA+ES+HALA A K  +E 
Sbjct: 521 YPGIGPEHAYLRDIGRVSYESITDKEAIEALQTLCQLEGILPAIESAHALAQAFKRAKEL 580

Query: 366 PDKEQLLVVNLSGRGDKDIFTVHDILKARGE 396
            +  + ++V LSGRGDKD+ T+  +L+    
Sbjct: 581 SEG-KTILVCLSGRGDKDVHTIQGVLEGDNN 610


>UniRef50_P00931 Tryptophan synthase n=45 Tax=Eukaryota RepID=TRP_YEAST
          Length = 707

 Score =  429 bits (1104), Expect = e-119,   Method: Composition-based stats.
 Identities = 204/390 (52%), Positives = 276/390 (70%), Gaps = 4/390 (1%)

Query: 8   YFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITA 67
            FG+FGG YVP+ L   LR+LE+ F  A  DP F   F  L  +Y GRP++L K + +T 
Sbjct: 305 RFGDFGGQYVPEALHACLRELEKGFDEAVADPTFWEDFKSLY-SYIGRPSSLHKAERLTE 363

Query: 68  GT-NTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALL 126
                 ++LKREDL H G+HK N  L Q LLAKR+GK  +IAETGAGQHGVA+A A A  
Sbjct: 364 HCQGAQIWLKREDLNHTGSHKINNALAQVLLAKRLGKKNVIAETGAGQHGVATATACAKF 423

Query: 127 GLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHY 186
           GL C ++MGA+DV RQ+ NVFRMR++GA+VI V +G+ TL+DA +EA R W  + +T +Y
Sbjct: 424 GLTCTVFMGAEDVRRQALNVFRMRILGAKVIAVTNGTKTLRDATSEAFRFWVTNLKTTYY 483

Query: 187 MLGTAAGPHPYPTIVREFQRMIGEETKAQILER-EGRLPDAVIACVGGGSNAIGMFADFI 245
           ++G+A GPHPYPT+VR FQ +IG+ETK Q      G+LPDAV+ACVGGGSN+ GMF+ F 
Sbjct: 484 VVGSAIGPHPYPTLVRTFQSVIGKETKEQFAAMNNGKLPDAVVACVGGGSNSTGMFSPFE 543

Query: 246 NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLD 305
           ++T+V L+GVE GG G++T  H A L  GR G++ G+K  ++Q  DGQ+ +++S+SAGLD
Sbjct: 544 HDTSVKLLGVEAGGDGVDTKFHSATLTAGRPGVFHGVKTYVLQDSDGQVHDTHSVSAGLD 603

Query: 306 FPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMREN 365
           +P VGP+ AY  STGRA +++ TD +AL  FK L   EGIIPALESSHA+  A ++ +  
Sbjct: 604 YPGVGPELAYWKSTGRAQFIAATDAQALLGFKLLSQLEGIIPALESSHAVYGACELAKTM 663

Query: 366 PDKEQLLVVNLSGRGDKDIFTVHDILKARG 395
              +Q LV+N+SGRGDKD+ +V ++L   G
Sbjct: 664 KP-DQHLVINISGRGDKDVQSVAEVLPKLG 692


>UniRef50_P25269 Tryptophan synthase beta chain 2, chloroplastic n=1628 Tax=cellular
           organisms RepID=TRBP2_ARATH
          Length = 475

 Score =  428 bits (1101), Expect = e-118,   Method: Composition-based stats.
 Identities = 215/392 (54%), Positives = 283/392 (72%), Gaps = 7/392 (1%)

Query: 7   PYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNIT 66
             FG+FGG YVP+ LM AL +LE AF S   D +FQ +  ++LK+Y GR + L   + +T
Sbjct: 84  GRFGKFGGKYVPETLMHALSELETAFYSLATDEDFQRELAEILKDYVGRESPLYFAERLT 143

Query: 67  AGT------NTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASA 120
                       +YLKREDL H GAHK N  + QALLAKR+GK  IIAETGAGQHGVA+A
Sbjct: 144 EHYRRENGEGPLIYLKREDLNHTGAHKINNAVAQALLAKRLGKKRIIAETGAGQHGVATA 203

Query: 121 LASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGS 180
              A  GL+C IYMGA+D+ERQ+ NVFRMRL+GAEV  VHSG+ATLKDA +EA+RDW  +
Sbjct: 204 TVCARFGLQCIIYMGAQDMERQALNVFRMRLLGAEVRGVHSGTATLKDATSEAIRDWVTN 263

Query: 181 YETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGM 240
            ET HY+LG+ AGPHPYP +VR+F  +IG+ET+ Q +E+ G  PD ++ACVGGGSNA+G+
Sbjct: 264 VETTHYILGSVAGPHPYPMMVRDFHAVIGKETRKQAMEKWGGKPDVLVACVGGGSNAMGL 323

Query: 241 FADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSI 300
           F +F+++T V +IGVE  G G+++G+H A L  G VG+  G  + ++Q +DGQI E +SI
Sbjct: 324 FHEFVDDTEVRMIGVEAAGFGLDSGKHAATLTKGDVGVLHGAMSYLLQDDDGQIIEPHSI 383

Query: 301 SAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALK 360
           SAGLD+P VGP+H++L   GRA+Y S+TD+EALEAFK +   EGIIPALE+SHALAH  K
Sbjct: 384 SAGLDYPGVGPEHSFLKDVGRAEYFSVTDEEALEAFKRVSRLEGIIPALETSHALAHLEK 443

Query: 361 MMRENPDKEQLLVVNLSGRGDKDIFTVHDILK 392
           +    PD  ++++ N SGRGDKD+ T    L+
Sbjct: 444 LCPTLPDGARVVL-NFSGRGDKDVQTAIKYLE 474


>UniRef50_Q7VR00 Tryptophan synthase beta chain n=5 Tax=Bacteria RepID=TRPB_BLOFL
          Length = 398

 Score =  428 bits (1101), Expect = e-118,   Method: Composition-based stats.
 Identities = 268/391 (68%), Positives = 325/391 (83%)

Query: 1   MTTLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALT 60
           MT  L+ YFGEFGGMYVPQIL+PAL QLE+ F+ A KD  FQ  F +LL +YAGRPT LT
Sbjct: 1   MTQQLHSYFGEFGGMYVPQILIPALIQLEKEFIEAMKDISFQTTFKNLLHHYAGRPTPLT 60

Query: 61  KCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASA 120
            CQN+T+GT + LYLKREDLLHGG+HKTNQVLGQALLAKRM K EIIAETGAGQHGVA +
Sbjct: 61  LCQNLTSGTCSKLYLKREDLLHGGSHKTNQVLGQALLAKRMHKKEIIAETGAGQHGVAVS 120

Query: 121 LASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGS 180
           +AS+LL LKCRIYMG KD++RQ  NV RM+LMG +VIPVH GSATLKDACNEA+R+WS +
Sbjct: 121 IASSLLKLKCRIYMGYKDMKRQELNVLRMKLMGTQVIPVHHGSATLKDACNEAIREWSST 180

Query: 181 YETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGM 240
           Y+  HYM+GT AGPHP+PTIV+EFQR+IG ET  QI   E +LPDAVIAC+GGGSNAIG+
Sbjct: 181 YKHTHYMIGTVAGPHPFPTIVKEFQRIIGSETYNQIQTHEKKLPDAVIACIGGGSNAIGI 240

Query: 241 FADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSI 300
           F+ FI+  +V L+GVE GG G+ T  HG+ L+ G  GIYFGMK+P++Q+++GQI+ SYSI
Sbjct: 241 FSGFIDIPSVQLLGVEAGGLGLHTEYHGSSLQCGETGIYFGMKSPILQSQEGQIKNSYSI 300

Query: 301 SAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALK 360
           +AGLDFPSVGP+HAYL    R  YVSI D+EA+ AF+ L L+EGIIPALES+HALAHALK
Sbjct: 301 AAGLDFPSVGPEHAYLKKINRVKYVSINDEEAINAFQELSLYEGIIPALESAHALAHALK 360

Query: 361 MMRENPDKEQLLVVNLSGRGDKDIFTVHDIL 391
           ++R+ P K+Q+L+VNLSGRGDKDI TV++ L
Sbjct: 361 IIRKTPKKKQILIVNLSGRGDKDIITVNNAL 391


>UniRef50_C9KJ78 Tryptophan synthase, beta subunit n=1 Tax=Mitsuokella multacida DSM
           20544 RepID=C9KJ78_9FIRM
          Length = 395

 Score =  426 bits (1096), Expect = e-118,   Method: Composition-based stats.
 Identities = 216/392 (55%), Positives = 277/392 (70%), Gaps = 3/392 (0%)

Query: 7   PYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNIT 66
             FG+FGG YVP+I+MPAL +LE A+   + DP+FQ +F   L+ YAGRPT L     +T
Sbjct: 5   GRFGKFGGQYVPEIVMPALNELEAAYAKYKDDPDFQNEFKTYLREYAGRPTNLYYADKLT 64

Query: 67  AGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASAL 125
                  ++LKREDLLH GAHK N  LGQALLAKRMGK  I+AETGAGQHGVASA  +AL
Sbjct: 65  KYYGRAKIFLKREDLLHTGAHKINNALGQALLAKRMGKKRIVAETGAGQHGVASATVAAL 124

Query: 126 LGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAH 185
            G++C ++MGA DVERQ  NVFRM+L+GA+VIPV SG+ TLKDA +EA+R W+ +    H
Sbjct: 125 FGMECHVFMGALDVERQKLNVFRMKLLGAKVIPVSSGTGTLKDATSEAIRYWATNITDTH 184

Query: 186 YMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFI 245
           Y++G+A GPHPYPTIVR+FQ++IGEE + Q +E+ G LPD ++ACVGGGSNAIG F DF 
Sbjct: 185 YIIGSAVGPHPYPTIVRDFQKVIGEEIREQAIEKIGGLPDYLLACVGGGSNAIGTFYDFR 244

Query: 246 NETNVGLIGVEPGGHGIETGEHGAPLK-HGRVGIYFGMKAPMMQTEDGQIEESYSISAGL 304
           N+ +V   GVE GG G    ++   L   G  GI  G  + ++Q  DGQ+ E+YSISAGL
Sbjct: 245 NDPSVKKFGVEAGGRGEAPTDNAKTLSGAGEPGILHGAFSYLLQDPDGQVVEAYSISAGL 304

Query: 305 DFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRE 364
           D+P VGP+H+Y    G   YVS+TD EAL+AF+ L   EGIIPA+ESSHALA+  K+M +
Sbjct: 305 DYPGVGPEHSYYKDEGIVKYVSVTDQEALDAFQRLSKVEGIIPAMESSHALAYLDKLMPQ 364

Query: 365 NPDKEQLLVVNLSGRGDKDIFTVHDILKARGE 396
               ++ +VV LSGRGDKD+  V  +L    E
Sbjct: 365 THP-DESVVVTLSGRGDKDVQMVAKVLGEDIE 395


>UniRef50_B1XY48 Tryptophan synthase beta chain n=287 Tax=cellular organisms
           RepID=TRPB_LEPCP
          Length = 428

 Score =  423 bits (1087), Expect = e-117,   Method: Composition-based stats.
 Identities = 210/385 (54%), Positives = 277/385 (71%), Gaps = 2/385 (0%)

Query: 7   PYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNIT 66
            +FG +GG +V + L  AL +L  A+   + DPEF A+F + L ++ GRP+ +     ++
Sbjct: 11  GHFGIYGGSFVAETLSHALDELNAAYERYRHDPEFIAEFRNELAHFVGRPSPVYHAARMS 70

Query: 67  AGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASAL 125
                  +YLKREDL H GAHK N  +GQALLA+RMGK  +IAETGAGQHGVA+A   A 
Sbjct: 71  REVGGAQIYLKREDLNHTGAHKINNTIGQALLARRMGKPRVIAETGAGQHGVATATICAR 130

Query: 126 LGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAH 185
            G++C +YMG++DV+RQSPNV+RM L+GA V+PV SGS TLKDA NEA+RDW  + E   
Sbjct: 131 YGMECVVYMGSEDVKRQSPNVYRMNLLGARVVPVESGSKTLKDALNEAMRDWVTNVENTF 190

Query: 186 YMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFI 245
           Y++GT AGPHPYP +VR+FQR+IG+E   Q+    GR PDAV+ACVGGGSNA+G+F  +I
Sbjct: 191 YIIGTVAGPHPYPAMVRDFQRVIGDECLVQMPALAGRQPDAVVACVGGGSNAMGIFYPYI 250

Query: 246 NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLD 305
               V LIGVE  G G+E+G+H A L+ G  G+  G +  ++Q  +GQI E++S+SAGLD
Sbjct: 251 PHEGVRLIGVEAAGEGMESGKHSASLQRGSPGVLHGNRTYVLQDANGQITETHSVSAGLD 310

Query: 306 FPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMREN 365
           +P VGP+HAYL   GRA+YV ITD EAL+AF  LC  EGIIPALESSHA+A+A+K+ +  
Sbjct: 311 YPGVGPEHAYLKDIGRAEYVGITDAEALQAFHYLCRAEGIIPALESSHAVAYAMKLAKTM 370

Query: 366 PDKEQLLVVNLSGRGDKDIFTVHDI 390
              +Q ++VNLSGRGDKDI TV D+
Sbjct: 371 RP-DQHVLVNLSGRGDKDIGTVADL 394


>UniRef50_B7FQI2 Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1
           RepID=B7FQI2_PHATR
          Length = 671

 Score =  414 bits (1065), Expect = e-114,   Method: Composition-based stats.
 Identities = 203/389 (52%), Positives = 273/389 (70%), Gaps = 3/389 (0%)

Query: 6   NPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNI 65
           N  FG+FGG Y+P+ L  A  ++E ++   + DP F A+ ++  +++ G PT L +   +
Sbjct: 281 NSRFGKFGGQYIPETLSVAFEEIEASYNELKDDPSFLAELDEYRRDFVGGPTPLHRADRL 340

Query: 66  TAGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASA 124
           T      T++LKREDL H GAHK N  +GQALLAKR+GK  IIAETGAGQHGVA+A   A
Sbjct: 341 TELAGGATIWLKREDLAHTGAHKINNAIGQALLAKRIGKPRIIAETGAGQHGVATATICA 400

Query: 125 LLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETA 184
            LGL C +YMGA D ERQ  NVFRM  +GA+V+PV  G  TLKDA NEA+RDW  +    
Sbjct: 401 KLGLDCTVYMGAVDCERQKLNVFRMNTLGAKVVPVQDGQRTLKDAINEAMRDWVTNVRDT 460

Query: 185 HYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADF 244
           HY++G+A GPHP+PTIVR+FQ ++G E +AQ+LER G+LPDAV+ACVGGGSNAIG F  F
Sbjct: 461 HYLIGSAVGPHPFPTIVRDFQSVMGREMRAQMLERAGKLPDAVVACVGGGSNAIGAFHPF 520

Query: 245 INETNVGLIGVEPGGHGIE-TGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAG 303
           +N+  V L GVE  G+GI+   EH A L  G  G+  G    ++Q + GQ   ++SISAG
Sbjct: 521 VNDETVELHGVEAAGYGIDKDEEHCATLTKGTPGVLQGAMTYVIQQKSGQTLNTHSISAG 580

Query: 304 LDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMR 363
           LD+P VGP+HA+L  +GRA Y ++TDDEALE FK +C +EGIIPALE+SHA+ +A+K+ +
Sbjct: 581 LDYPGVGPEHAFLKDSGRAVYEAVTDDEALEGFKLMCEYEGIIPALETSHAIYYAVKLAK 640

Query: 364 ENPDKEQLLVVNLSGRGDKDIFTVHDILK 392
           +    +  +V+N+SGRGDKD+  +  I+ 
Sbjct: 641 KLGPGKD-IVINMSGRGDKDMPQIAKIMG 668


>UniRef50_A8Z5Y3 Putative tryptophan synthase, beta subunit (TrpB)/anthranilate
           isomerase activity of trpC (TrpF) n=1 Tax=Candidatus
           Sulcia muelleri GWSS RepID=A8Z5Y3_SULMW
          Length = 595

 Score =  414 bits (1064), Expect = e-114,   Method: Composition-based stats.
 Identities = 183/387 (47%), Positives = 255/387 (65%), Gaps = 8/387 (2%)

Query: 6   NPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNI 65
           + ++G FGG Y+P++L   +  L+  +     +  F+ +   LL NY GRP+ L  C N+
Sbjct: 214 HGFYGNFGGAYIPEMLYNNINHLKNEYNKIINNNCFKKKLKRLLHNYVGRPSPLFYCNNL 273

Query: 66  TAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASAL 125
           +      +YLKREDL H G+HK N  +GQALLAK +GK  II+ETGAGQHGVA++   +L
Sbjct: 274 SKIYGAKIYLKREDLNHTGSHKINNTIGQALLAKEIGKKNIISETGAGQHGVATSTICSL 333

Query: 126 LGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAH 185
           LGLKC I+MG  D++RQ  NV+RM+++GA +I V+SGS TLKD+ NEA+R W  +    +
Sbjct: 334 LGLKCTIFMGEVDIKRQIQNVYRMKMLGANIIAVNSGSKTLKDSVNEAIRYWI-NNPDCY 392

Query: 186 YMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFI 245
           YM+G+A GP PYP +V  FQ +I EE K Q+ E    LP+ +IAC+GGGSNA G+F  F+
Sbjct: 393 YMIGSAVGPDPYPRMVSYFQSIISEEIKEQLKE----LPNYIIACLGGGSNAAGIFYHFL 448

Query: 246 NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLD 305
           ++  V LIGVE  G G+ T +  A ++ G  G+  G    +MQ + GQI E YSISAGLD
Sbjct: 449 DDEYVKLIGVEASGLGLNTNKTAATIQKGSRGVLHGSMTILMQDKYGQILEPYSISAGLD 508

Query: 306 FPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMREN 365
           +P +GP HA L    RA ++S+TD EA+EA   L   EGIIPALES+HA+A   K+  + 
Sbjct: 509 YPGIGPMHANLFYKNRATFISVTDFEAIEAGIELSSLEGIIPALESAHAIASLKKLSFK- 567

Query: 366 PDKEQLLVVNLSGRGDKDIFTVHDILK 392
             K  L+++N+SGRGDKD+ T    ++
Sbjct: 568 --KNDLVIINMSGRGDKDMDTYIKHIE 592


>UniRef50_D0JB95 Bifunctional phosphoribosylanthranilate isomerase/tryptophan
           synthase subunit beta n=1 Tax=Blattabacterium sp.
           (Blattella germanica) str. Bge RepID=D0JB95_BLASB
          Length = 610

 Score =  412 bits (1059), Expect = e-113,   Method: Composition-based stats.
 Identities = 187/389 (48%), Positives = 253/389 (65%), Gaps = 7/389 (1%)

Query: 5   LNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQN 64
            N Y+GEFGG ++P++L   + +L++ +       EFQ  +  +LKNYAGRPT L  C+ 
Sbjct: 217 KNGYYGEFGGAFIPEMLHHNITELQDQYKKFITSFEFQKLYKKILKNYAGRPTPLFFCKK 276

Query: 65  ITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASA 124
            +      +YLKREDL H G+HK N  +GQALLAK++GK +IIAETGAGQHGVA+A   A
Sbjct: 277 YSDKYKAKIYLKREDLNHTGSHKINNSIGQALLAKQLGKKKIIAETGAGQHGVATATTCA 336

Query: 125 LLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETA 184
           L+ L+C I+MG  D+ RQ  NV RM+ +GA+VIPV SG  TLKDA NEA+R W  S+  +
Sbjct: 337 LMNLECIIFMGETDIHRQYTNVLRMKSLGAKVIPVCSGDKTLKDAVNEAIRYWI-SHPES 395

Query: 185 HYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREG-RLPDAVIACVGGGSNAIGMFAD 243
           +Y++G+  GPHPYP +V + Q +I EE K Q+ E+EG   P+ V+AC+GGGSNA G F  
Sbjct: 396 YYLIGSTVGPHPYPQMVADIQSIISEEIKIQLKEKEGSSFPNYVVACIGGGSNAAGSFYH 455

Query: 244 FINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAG 303
           F++  +V L+ VE  G G+ T +  A +  G  GI  G    ++Q EDGQ+  ++SISAG
Sbjct: 456 FLDNDSVNLVAVEAAGLGVNTKKTAASIHCGSRGILHGSMTMLLQNEDGQVLPAHSISAG 515

Query: 304 LDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMR 363
           LD+P +GP  A L    R +++  TD+EAL+A   L   EGIIPALESSHALA      +
Sbjct: 516 LDYPGIGPMFANLFVKKRVNFLHSTDEEALQAGYELTRLEGIIPALESSHALAAL----K 571

Query: 364 ENPDKE-QLLVVNLSGRGDKDIFTVHDIL 391
             P K+  ++VV LSGRGDKDI       
Sbjct: 572 NIPFKKMDVVVVTLSGRGDKDINVYDKFF 600


>UniRef50_A1KSW2 Tryptophan synthase beta chain n=49 Tax=Bacteria RepID=TRPB_NEIMF
          Length = 400

 Score =  412 bits (1058), Expect = e-113,   Method: Composition-based stats.
 Identities = 208/386 (53%), Positives = 276/386 (71%), Gaps = 3/386 (0%)

Query: 7   PYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNIT 66
            +FGE GG++V + L+PAL++L +A+ +A+ DPEF   F   LK+Y GRP+ +     ++
Sbjct: 11  GFFGEHGGLFVSETLIPALQELADAYKAAKNDPEFWEAFRHDLKHYVGRPSPVYHAARLS 70

Query: 67  AGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASAL 125
                  ++LKREDL H GAHK N  +GQALLAKRMGK  +IAETGAGQHGVASA  +A 
Sbjct: 71  EHLGGAQIWLKREDLNHTGAHKVNNTIGQALLAKRMGKKRVIAETGAGQHGVASATVAAR 130

Query: 126 LGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAH 185
            G+ C +YMGA D++RQ PNVFRM+L+GA V+ V SGS TLKDA NEA+R+W    +   
Sbjct: 131 FGMTCDVYMGADDIQRQMPNVFRMKLLGANVVGVESGSRTLKDAMNEAMREWVARVDDTF 190

Query: 186 YMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFI 245
           Y++GTAAGP PYP +VR+FQ +IG E KAQ+ E  GR PD  +ACVGGGSNAIG+F  +I
Sbjct: 191 YIIGTAAGPAPYPEMVRDFQCVIGNEAKAQMQEAIGRQPDVAVACVGGGSNAIGLFHPYI 250

Query: 246 NETNVGLIGVEPGGHGIETGEHGAPLKHGRV-GIYFGMKAPMMQTEDGQIEESYSISAGL 304
            E NV L+GVE GG G+ T +H AP+  G   G+  G ++ +MQ E+GQ+  ++S+SAGL
Sbjct: 251 GEENVRLVGVEAGGLGVNTPDHAAPITSGAPIGVLHGFRSYLMQDENGQVLGTHSVSAGL 310

Query: 305 DFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRE 364
           D+P +GP+H++L+   R +Y    DDEALEAF  LC  EGIIPALESSHA+A A+K   +
Sbjct: 311 DYPGIGPEHSHLHDIKRVEYTVAKDDEALEAFDLLCRFEGIIPALESSHAVAWAVKNAPK 370

Query: 365 NPDKEQLLVVNLSGRGDKDIFTVHDI 390
              K+Q+++VNLSGRGDKDI TV  +
Sbjct: 371 M-GKDQVILVNLSGRGDKDINTVAKL 395


>UniRef50_C5V964 Tryptophan synthase, beta subunit n=2 Tax=Corynebacterium
           matruchotii RepID=C5V964_9CORY
          Length = 453

 Score =  409 bits (1052), Expect = e-113,   Method: Composition-based stats.
 Identities = 235/393 (59%), Positives = 306/393 (77%), Gaps = 3/393 (0%)

Query: 3   TLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKC 62
           TL++ YFGE+GG YVP++L P+L QLE+A+V A  DPEF  + +DL +NY GRPT +T+C
Sbjct: 14  TLIDAYFGEYGGQYVPEVLYPSLDQLEQAYVDALNDPEFLRELDDLRRNYLGRPTPITEC 73

Query: 63  QNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALA 122
            N+    N  ++LKREDLLHGGAHK NQVL QALLAKRMGKT +IAETGAGQHG+A+A+ 
Sbjct: 74  ANLPLSGNARIFLKREDLLHGGAHKGNQVLAQALLAKRMGKTRLIAETGAGQHGMATAMV 133

Query: 123 SALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS-GSATLKDACNEALRDWSGSY 181
           +AL+G++C IYMGA+DV RQ PNV+RMRLMGA+V+PV +     L DA + AL DW  S 
Sbjct: 134 AALMGMECTIYMGARDVARQQPNVYRMRLMGAKVVPVSNEHGEALSDAIDVALADWVESL 193

Query: 182 ETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMF 241
            T HY+LGTAAGPHP+P +V++FQ++I EE++ Q+LER GRLPDAV+ACVGGGSNAIG F
Sbjct: 194 GTTHYLLGTAAGPHPFPKLVKQFQKVISEESRQQMLERTGRLPDAVVACVGGGSNAIGAF 253

Query: 242 ADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSIS 301
           A+++ +  V LIGVEP G G+++G+HGAPL  G+VG+  G K+ +M   DG++  S+S+S
Sbjct: 254 AEYLPDEEVRLIGVEPAGEGLDSGKHGAPLNRGKVGVLHGSKSYVMLGSDGEVMHSHSVS 313

Query: 302 AGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKM 361
           AGLD+P VGP+HAYL  +GRA+YV ITD EAL+AF+ L  +EGIIPALESSHALA+ALK+
Sbjct: 314 AGLDYPGVGPEHAYLLDSGRAEYVGITDAEALQAFRMLSWYEGIIPALESSHALAYALKL 373

Query: 362 MRENPDKEQL--LVVNLSGRGDKDIFTVHDILK 392
                 + +   ++VNLSGRGDKD+  V  IL 
Sbjct: 374 AEHADPQGEPLNILVNLSGRGDKDVDYVRHILG 406


>UniRef50_A5UMB9 Tryptophan synthase, beta subunit, TrpB n=5 Tax=cellular organisms
           RepID=A5UMB9_METS3
          Length = 593

 Score =  407 bits (1045), Expect = e-112,   Method: Composition-based stats.
 Identities = 208/386 (53%), Positives = 279/386 (72%), Gaps = 2/386 (0%)

Query: 6   NPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNI 65
           N  +GE+GG Y+ + LM  L  LEE +     D EF  + N LLK YAGRP+ L   + +
Sbjct: 202 NGRYGEYGGQYISETLMNELIYLEEQYYHYMNDSEFVEELNTLLKEYAGRPSLLYYAKRM 261

Query: 66  TAGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASA 124
           T       +YLKREDL H GAHK N VLGQ LLAK+MGKT +IAETGAGQHGVA+A A+A
Sbjct: 262 TEDLGGAKIYLKREDLNHTGAHKINNVLGQVLLAKKMGKTRVIAETGAGQHGVATATAAA 321

Query: 125 LLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETA 184
           LL ++C +YMG  D +RQ+ NV+RM L+GA+V PV SG+ TLKDA N+A RDW G     
Sbjct: 322 LLDMECEVYMGELDTKRQALNVYRMELLGAKVHPVKSGTKTLKDAVNDAFRDWIGRVHDT 381

Query: 185 HYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADF 244
           +Y++G+  GPHP+P +VR+FQ +I  E + Q LE+EG+LPDAV+ACVGGGSNA+G F +F
Sbjct: 382 NYVIGSTMGPHPFPMMVRDFQAVISAEAREQFLEKEGKLPDAVLACVGGGSNAMGAFYNF 441

Query: 245 INETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGL 304
           I++ +V LIG E GG G++T  + A L +G++GI+ GMK+   Q E GQI E YS+SAGL
Sbjct: 442 IDDADVKLIGCEAGGKGVDTPYNAAALTNGQIGIFHGMKSIFNQGEYGQISEVYSVSAGL 501

Query: 305 DFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRE 364
           D+P VGP+HAYL    RA+YV +TD+EA+ AF+ L   EGIIPA+ES+HA+AHA+K+  +
Sbjct: 502 DYPGVGPEHAYLRDIKRAEYVPVTDEEAVNAFEYLSKMEGIIPAIESAHAVAHAMKIAPK 561

Query: 365 NPDKEQLLVVNLSGRGDKDIFTVHDI 390
             DK+++++V LSGRGDKD+ ++   
Sbjct: 562 M-DKDEIIMVCLSGRGDKDVASIAKY 586


>UniRef50_D1HPU5 Whole genome shotgun sequence of line PN40024,
           scaffold_116.assembly12x (Fragment) n=2 Tax=Vitis
           vinifera RepID=D1HPU5_VITVI
          Length = 407

 Score =  405 bits (1042), Expect = e-111,   Method: Composition-based stats.
 Identities = 193/393 (49%), Positives = 262/393 (66%), Gaps = 10/393 (2%)

Query: 7   PYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNIT 66
             FG FGG +VP+ LM  L +LE  F     DPEFQ +    L++Y GR T L   Q +T
Sbjct: 6   GKFGRFGGKFVPETLMTCLSKLEAEFNLVLHDPEFQEELATALRDYVGRETPLYFAQRLT 65

Query: 67  AG------TNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASA 120
                       +YLKREDL HGGAHK N  + QA++AKRMG+T I+A TGAGQHGVA+A
Sbjct: 66  DHYKNESGCGPEIYLKREDLNHGGAHKINNAIAQAMIAKRMGRTSIVAATGAGQHGVATA 125

Query: 121 LASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGS 180
            A A L LKC I MG  D+ERQ+ NV  M+L+GAEV  V       K+A +EA+R+W G+
Sbjct: 126 AACAKLSLKCTIVMGTLDMERQASNVLLMKLLGAEVKSVDGN---FKNATSEAIREWVGN 182

Query: 181 YETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGM 240
            ET ++++GTA GPHP P++VREFQ +IG+ET+ Q +ER GR PD ++ACVG GSNA+G+
Sbjct: 183 LETNYFLIGTAVGPHPCPSMVREFQSIIGKETRRQAMERWGRKPDVLVACVGSGSNALGL 242

Query: 241 FADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSI 300
           F +FI + +V +IGVE  G G+E+G+H A L  G VG+Y G  + ++Q E+GQI   +SI
Sbjct: 243 FHEFIADEDVRMIGVEAAGFGLESGKHSATLAKGEVGVYHGAMSYLLQDEEGQIVGPHSI 302

Query: 301 SAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALK 360
             G+++P V P+ ++L  TGR +  S+TD EA++A++ LC  EGI PALE+SHALA   K
Sbjct: 303 GVGMEYPGVSPELSFLKETGRVESYSVTDQEAVDAYQLLCRLEGIFPALEASHALAFLDK 362

Query: 361 MMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
           +    PD  +++V N SGRGDKD  TV  + + 
Sbjct: 363 LCPTLPDGGKVVV-NCSGRGDKDAPTVFRLTQG 394


>UniRef50_Q2S700 Tryptophan synthase, beta subunit n=6 Tax=Bacteria
           RepID=Q2S700_HAHCH
          Length = 426

 Score =  397 bits (1020), Expect = e-109,   Method: Composition-based stats.
 Identities = 208/395 (52%), Positives = 266/395 (67%), Gaps = 4/395 (1%)

Query: 1   MTTLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALT 60
           M    N  FG FGG Y P+IL PAL +LE  F S + DP+F  ++  L + ++GRPT LT
Sbjct: 1   MIRSNNGMFGSFGGRYAPEILTPALIELERLFFSLRDDPDFWREYQTLAQQFSGRPTPLT 60

Query: 61  KCQNITAGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVAS 119
            C+ ++       ++LKREDL H GAHK N VLGQ LL +RMGK  +IAETGAGQHG+A+
Sbjct: 61  PCERLSREIGGAQIWLKREDLNHSGAHKVNNVLGQGLLVRRMGKRRVIAETGAGQHGLAT 120

Query: 120 ALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSG 179
           A+ +A LGL+CRIYMG  D+ERQ  NVF MR +GAEVIPV +G+ TLK+A +EALRDW+ 
Sbjct: 121 AIMAARLGLECRIYMGEDDIERQYGNVFWMRRLGAEVIPVATGARTLKEAMDEALRDWAA 180

Query: 180 SYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIG 239
           S+E  HY+LGTA GP P+P +V  FQ +IG+E + Q L + GR PD+V+ACVGGGSNA+G
Sbjct: 181 SFEDTHYVLGTACGPAPFPELVAYFQSIIGKELQQQALSQIGRNPDSVVACVGGGSNALG 240

Query: 240 MFADFINETNVGLIGVEPGGHGIETGEHGAPLKH--GRVGIYFGMKAPMMQTEDGQIEES 297
            FA FI   +V L+GVE GG   E G+H   L+   G  GI  G K   +Q  DGQ+  +
Sbjct: 241 AFAPFIERHDVELVGVEAGGRSREEGQHSIRLQEGTGEDGIAQGFKTLFLQDADGQLGHT 300

Query: 298 YSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAH 357
           +S++AGLD+  V P  A L   GR    S TD+EAL AF+TL  +EGIIPALESSHALA 
Sbjct: 301 HSVAAGLDYVGVSPILADLTQRGRLTPDSATDEEALAAFETLLRYEGIIPALESSHALAG 360

Query: 358 ALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILK 392
             +   +   + Q +V+NLSGRGDKDIF V     
Sbjct: 361 GFRRAAQMSPQ-QHMVINLSGRGDKDIFNVARAFP 394


>UniRef50_Q7VGA7 Tryptophan synthase beta chain n=4 Tax=Proteobacteria
           RepID=TRPB_HELHP
          Length = 420

 Score =  392 bits (1006), Expect = e-107,   Method: Composition-based stats.
 Identities = 194/399 (48%), Positives = 255/399 (63%), Gaps = 11/399 (2%)

Query: 2   TTLLNPYFGE-------FGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAG 54
           T   N YFGE       FGG Y+P+IL+PAL++LE+A+        ++ +   L K++ G
Sbjct: 7   TESKNGYFGEAKGGNHAFGGQYIPEILLPALKELEKAYHGVFVSKAYKKELKSLFKHFVG 66

Query: 55  RPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQ 114
           RPT L    N +      +YLK E L + GAHK N  LGQ LLAK M K  +IAETGAGQ
Sbjct: 67  RPTPLIYAHNASKILKNDIYLKFEGLANTGAHKINNALGQVLLAKHMKKKRVIAETGAGQ 126

Query: 115 HGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEAL 174
           HG+A+A A A LGL+C I+MG  D+ RQ PNVF M L GA+V  V SGS TLKDA NEAL
Sbjct: 127 HGLATAAACARLGLECEIFMGEIDIARQRPNVFNMELFGAKVHSVSSGSKTLKDAVNEAL 186

Query: 175 RDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGG 234
           R+WS   + + Y+LG+A GP+PYP IVR+ Q +I +E K Q       LPD ++ACVGGG
Sbjct: 187 REWSKRSDDSFYVLGSALGPYPYPDIVRDLQSVISKELKKQTKAYFSSLPDILVACVGGG 246

Query: 235 SNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKH--GRVGIYFGMKAPMMQTEDG 292
           SNA+G F  ++ E  V LIGVE GG G + GE+   +       GI  G K+  +Q +DG
Sbjct: 247 SNAMGFFTHYLKEERVRLIGVEAGGIGDKEGENAIRINTINASEGIAQGYKSLFLQDKDG 306

Query: 293 QIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESS 352
           Q+ +++SISAGLD+  +GPQ A+L   GR ++ S TD EALEA      +EGIIPALESS
Sbjct: 307 QLSDTHSISAGLDYAGIGPQLAHLYEVGRVEFQSATDKEALEALSFFAQYEGIIPALESS 366

Query: 353 HALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDIL 391
           HALA  +++ ++   K+  ++ N+SGRGDKDIF     L
Sbjct: 367 HALAAVIRLCKDIKGKK--IIANISGRGDKDIFITAKAL 403


>UniRef50_B2TM49 Tryptophan synthase beta chain n=40 Tax=cellular organisms
           RepID=TRPB_CLOBB
          Length = 405

 Score =  392 bits (1006), Expect = e-107,   Method: Composition-based stats.
 Identities = 181/387 (46%), Positives = 257/387 (66%), Gaps = 4/387 (1%)

Query: 5   LNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQN 64
            N  FG++GG Y+   L+PA  ++ +A+ +     +F  +   + K + GRPT +  C+ 
Sbjct: 13  KNGRFGQYGGAYLTAELIPAFEEIADAYQTICHSSQFINELRRIRKEFQGRPTPVYHCER 72

Query: 65  ITAGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALAS 123
           ++       +YLKREDL H GAHK N  +G+ LLAK MGK  +IAETGAGQHGVA A A+
Sbjct: 73  LSRAIGNCQIYLKREDLNHTGAHKLNHCMGEGLLAKFMGKKRLIAETGAGQHGVALATAA 132

Query: 124 ALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYET 183
           A  GL+C I+MG  D+ +Q+PNV RM+++GA+V+PV  G  TLK+A + A   ++ +Y+ 
Sbjct: 133 AFFGLECEIHMGEVDIAKQAPNVTRMKILGAKVVPVTHGLKTLKEAVDSAFDSYAKNYKD 192

Query: 184 AHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFAD 243
           + Y +G+A GPHP+P +VR+FQ ++G E K Q  E  G LPD V ACVGGGSNA GMF  
Sbjct: 193 SIYCIGSALGPHPFPLMVRDFQAVVGYEAKDQFKEMTGFLPDVVTACVGGGSNAAGMFIP 252

Query: 244 FINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAG 303
           F+ E  V +IG+EP G G + G+H A +K+G  G+  G ++ M++ ++G     YSI++G
Sbjct: 253 FLEEP-VDIIGIEPLGRGEKLGDHAASMKYGEKGVMHGFESIMLKDKNGDPAPVYSIASG 311

Query: 304 LDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMR 363
           LD+PSVGP+HA+L   GR DY  I D+EA+EAF  L  +EGIIPA+ESSHA+A+A+K   
Sbjct: 312 LDYPSVGPEHAFLRELGRVDYKVINDEEAMEAFFKLSRYEGIIPAIESSHAVAYAMKKAE 371

Query: 364 ENPDKEQLLVVNLSGRGDKDIFTVHDI 390
           E       ++V LSGRGDKDI  + + 
Sbjct: 372 EMKQGS--ILVCLSGRGDKDIDYIVEH 396


>UniRef50_D2VKV7 Predicted protein n=1 Tax=Naegleria gruberi RepID=D2VKV7_NAEGR
          Length = 434

 Score =  383 bits (985), Expect = e-105,   Method: Composition-based stats.
 Identities = 191/407 (46%), Positives = 262/407 (64%), Gaps = 23/407 (5%)

Query: 5   LNPYFG-------EFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPT 57
           +N  +G       +FGG +VP  L   L +L + F+  + D EF  +F DLL+++ GRPT
Sbjct: 31  MNGIYGITKDESCQFGGCHVPPQLQKVLERLRDEFLKYKDDEEFNKEFRDLLRDFVGRPT 90

Query: 58  ALTKCQNITAGTN--TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
            L+  +N          +YLKRED  H G+HK N  +GQ LLAKRMG   IIAETGAGQH
Sbjct: 91  PLSPARNFAKQLGTNAKIYLKREDTAHLGSHKINNCIGQILLAKRMGAKRIIAETGAGQH 150

Query: 116 GVASALASALLG-LKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEAL 174
           G A A   AL G ++C IYMGA+D  RQS NVFRM+++GA+VIPV  G   L+DA +EAL
Sbjct: 151 GSAVAAVCALFGNIECVIYMGAEDCRRQSLNVFRMQMLGAKVIPVTKGQGRLRDAVDEAL 210

Query: 175 RDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGG 234
            D   +YE   Y+LG+A GP P+P +V+ FQ +I EE++ QIL+ E +LP  VIACVGGG
Sbjct: 211 GDLVQNYENTFYLLGSAVGPCPFPNMVKHFQSVISEESRQQILQAENKLPTMVIACVGGG 270

Query: 235 SNAIGMFADFI---NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTED 291
           SNAIG F+ ++    +  V L+G+EP             L  G   I  G K+  +  E+
Sbjct: 271 SNAIGAFSHYLRKGEDEKVRLLGIEPI--------EAPTLTEGVPYILHGFKSLCLLDEN 322

Query: 292 GQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALES 351
           G+ +++YS++AGLD+PSVG  H+YL S GR +Y +++  + LEAF  L   EGIIPALES
Sbjct: 323 GEPKKTYSVAAGLDYPSVGSIHSYLKSIGRCEYYTVSKKQVLEAFMLLSKSEGIIPALES 382

Query: 352 SHALAHALKMMRENPDK-EQLLVVNLSGRGDKDIFTVHDILKARGEI 397
           SHALA+ ++M + N  K + ++VVNLSGRGDKD+  V+D++  +GE 
Sbjct: 383 SHALAYVVEMAKNNQLKDDDIVVVNLSGRGDKDVEQVYDMI-KKGEF 428


>UniRef50_B2KCI5 Tryptophan synthase beta chain n=2 Tax=Bacteria RepID=TRPB_ELUMP
          Length = 412

 Score =  383 bits (983), Expect = e-105,   Method: Composition-based stats.
 Identities = 188/389 (48%), Positives = 266/389 (68%), Gaps = 2/389 (0%)

Query: 6   NPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNI 65
           + ++G +GG++VP+ L+  L ++ + F +     EFQ +     KNY GRP+ L    NI
Sbjct: 21  HGFYGIYGGVFVPKELIVPLAEIADCFNNTAFTKEFQDELFYYYKNYVGRPSPLYYAANI 80

Query: 66  TAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASAL 125
           + G    +YLKREDL H GAHK N  +G+ LLAK+MGK  +IAETGAGQHG+A A A+AL
Sbjct: 81  SCG-GAKIYLKREDLNHTGAHKINHCIGEVLLAKKMGKKRVIAETGAGQHGIAIATAAAL 139

Query: 126 LGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAH 185
           LG++C IYMG +DV+++ PNV +++ +GA+V+ V SG+  LK+A + A  D+    ET  
Sbjct: 140 LGIECVIYMGEQDVKKEYPNVLKIKTLGAKVVCVGSGAKGLKEAVDAAFDDYLKDPETQM 199

Query: 186 YMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFI 245
           Y +G+  GPHP+P +V  FQ ++G+E + Q LE+EGRLPD V+ACVGGGSN++G+F+ F 
Sbjct: 200 YAIGSVVGPHPFPLMVASFQSIVGKEAREQFLEQEGRLPDNVVACVGGGSNSMGIFSGFF 259

Query: 246 NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLD 305
            +  V L GVEP G G+ETG H APL  GRVG+  G K   MQ + G    ++S+++GLD
Sbjct: 260 ADKTVKLTGVEPAGKGLETGLHAAPLAKGRVGVVHGFKCYFMQDDKGNPMGTHSVASGLD 319

Query: 306 FPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMREN 365
           +  VGPQH YL  +GR  Y S  DDEA++AF  L   EGIIPALES+HA+A+ALK+ +E 
Sbjct: 320 YLGVGPQHCYLKDSGRVTYRSACDDEAVDAFFMLSRKEGIIPALESAHAVAYALKLSKEL 379

Query: 366 PDKEQLLVVNLSGRGDKDIFTVHDILKAR 394
             K++ ++VNLSGRG+KD+  V  +   +
Sbjct: 380 -GKDKSILVNLSGRGEKDLDYVLSLYGKK 407


>UniRef50_Q822W9 Tryptophan synthase beta chain 1 n=8 Tax=Bacteria RepID=TRPB1_CHLCV
          Length = 412

 Score =  382 bits (980), Expect = e-104,   Method: Composition-based stats.
 Identities = 202/385 (52%), Positives = 270/385 (70%), Gaps = 2/385 (0%)

Query: 12  FGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGT-N 70
           +GG YVP  L+  L  L+ ++   +KDP+F+  F+ +LKNYAGRPT LT+ +N +     
Sbjct: 27  YGGQYVPLELVKPLEDLDRSYEQLKKDPQFRETFHHILKNYAGRPTPLTEVKNFSRAING 86

Query: 71  TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKC 130
             ++LKREDLLH GAHK N VLGQ L+AK  GKT ++AETGAGQHGVA A A+A LG++C
Sbjct: 87  PRIFLKREDLLHTGAHKINNVLGQCLIAKFQGKTRVVAETGAGQHGVALAAAAAYLGMEC 146

Query: 131 RIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGT 190
            I+MG  D+ RQ PNV R+R++GAEV+ V  G++ LK+A + A+ D+   ++  H+ +G+
Sbjct: 147 VIFMGETDINRQKPNVDRIRVLGAEVVSVKRGNSGLKEAVDAAIEDFIFKHDHTHFCIGS 206

Query: 191 AAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNV 250
           A GP+PYP IVR+FQ +I  E K+QI E   R PD +IACVGGGSNAIG F  FI  T V
Sbjct: 207 ALGPYPYPKIVRDFQSVISLEVKSQIKEYTDRDPDILIACVGGGSNAIGFFHHFIPNTKV 266

Query: 251 GLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVG 310
            L+GVE GG G+E+G+H A    G+ G+  G  + ++Q EDG   ++YSISAGLD+ SVG
Sbjct: 267 KLVGVEGGGLGVESGKHAARFATGKPGVVHGFHSYVLQDEDGNCADTYSISAGLDYVSVG 326

Query: 311 PQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQ 370
           P HA ++ +GRA Y   TDDEALEAF+ L   EGIIPALESSHALAH +K+     DK+ 
Sbjct: 327 PTHAEMHESGRAQYTYATDDEALEAFRLLSKTEGIIPALESSHALAHMIKIAPSL-DKDT 385

Query: 371 LLVVNLSGRGDKDIFTVHDILKARG 395
           + +VNLSGRGDKD+  + D+ K + 
Sbjct: 386 IAIVNLSGRGDKDLSQIIDLDKRKK 410


>UniRef50_B0ZSJ6 Tryptophan synthase beta subunit n=3 Tax=rosids RepID=B0ZSJ6_SOYBN
          Length = 461

 Score =  380 bits (975), Expect = e-104,   Method: Composition-based stats.
 Identities = 175/394 (44%), Positives = 257/394 (65%), Gaps = 11/394 (2%)

Query: 3   TLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKC 62
           +  +  FG FGG +VP+ L+ +L QLE  F +A +D  FQA+  + L++YAGR T L   
Sbjct: 67  STTSGKFGRFGGKFVPETLVASLTQLEAEFKNALRDHAFQAELAEALRDYAGRETPLYHA 126

Query: 63  QNITA-------GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           + ++        G    +YLKREDL H G+HK N  L QA++AKRMG   ++  TG+GQH
Sbjct: 127 KRLSEYYKSVNNGKGPDIYLKREDLNHSGSHKMNNALAQAMIAKRMGCKSVVTATGSGQH 186

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
           G+A+A A A L L C ++M  KD+ RQ  NV  ++L+GA+V  V  G     DA +EA R
Sbjct: 187 GLATAAACAKLALDCTVFMADKDIHRQYSNVRLIKLLGAQVEAVDGG---FTDAASEAFR 243

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
            W G  E  +++ G+A GPHP PT+VREFQ +IG+ET+ Q LE+ G  PD ++A VG GS
Sbjct: 244 YWVGDLENRYHLSGSAVGPHPCPTMVREFQSVIGKETRMQALEKWGGKPDVLVASVGTGS 303

Query: 236 NAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIE 295
           NA+G+F +FI + +V  +GVE GG G+E+G+H + L  G VG Y G  + ++Q +DGQI 
Sbjct: 304 NALGLFHEFIADKDVRFVGVEAGGLGLESGKHSSTLTTGEVGAYHGAISYLLQDQDGQII 363

Query: 296 ESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHAL 355
             +SI+AG+++P VGP+ ++L  +GRA++    D+EAL+A++ LC  EGI P+LE++HAL
Sbjct: 364 HPHSIAAGMEYPGVGPELSFLKESGRAEFCVANDEEALDAYQRLCKLEGIFPSLEAAHAL 423

Query: 356 AHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHD 389
           A   K++    +  +++V N SGRGDKD   V +
Sbjct: 424 AILDKLVPTLCNGTKVVV-NCSGRGDKDAAIVFN 456


>UniRef50_C1FGK1 Predicted protein n=14 Tax=cellular organisms RepID=C1FGK1_9CHLO
          Length = 444

 Score =  373 bits (959), Expect = e-102,   Method: Composition-based stats.
 Identities = 181/392 (46%), Positives = 259/392 (66%), Gaps = 4/392 (1%)

Query: 6   NPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNI 65
           + YFGE+GG ++P  L+P + +++  +   ++DP F A+   L K++ GRP+ +  C+ +
Sbjct: 34  DGYFGEYGGAFLPPPLVPIIDEIKAKYNELKEDPSFWAELRLLEKHFTGRPSPILHCERL 93

Query: 66  TAGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASA 124
           +       +YLKREDL H GAHK N  LG+ALLAK+MGK ++IAETGAGQHGVA A A+A
Sbjct: 94  SEKIGGAQIYLKREDLNHTGAHKINHCLGEALLAKKMGKKKLIAETGAGQHGVALATAAA 153

Query: 125 LLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETA 184
           L+GL+C IYMG  D+ ++ PNV RM+++GA VIP   G  TLK+A + A   +     T 
Sbjct: 154 LVGLECDIYMGEVDMAKERPNVVRMKILGANVIPASHGLKTLKEAVDAAFGAYMEDPVTQ 213

Query: 185 HYMLGTAAGPHPYPTIVREFQRMIGEETKAQILER-EGRLPDAVIACVGGGSNAIGMFAD 243
            Y +G+  GPHP+P +VR+FQ ++G E K Q  E   G+LPD ++ACVGGG NAIG+F  
Sbjct: 214 FYAIGSVVGPHPFPAMVRDFQSVVGREAKEQFKELTGGKLPDNLVACVGGGCNAIGLFTA 273

Query: 244 FINETNVGLIGVEPGGHGIET-GEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISA 302
           F+ +  V + GVEP G  ++T G+H A L  G  G+  G K  ++Q E G+     + ++
Sbjct: 274 FLGDEKVKMFGVEPSGTDLKTVGKHAATLTLGTPGVIHGFKCVLLQDEGGEPAAVNTCAS 333

Query: 303 GLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMM 362
           GLD+P VGPQH YL   GR  Y + TD E ++AF +L   +GIIPALESSHA+A+A+K+ 
Sbjct: 334 GLDYPGVGPQHCYLKDIGRVKYETATDVECVDAFMSLARDQGIIPALESSHAVAYAIKLA 393

Query: 363 RENPDKEQLLVVNLSGRGDKDIFTVHDILKAR 394
           +  P K + ++VNLSGRGDKD+  V +   A+
Sbjct: 394 KTLP-KTETILVNLSGRGDKDVDYVVENFGAK 424


>UniRef50_C0NSJ2 Bifunctional tryptophan synthase TRPB n=1 Tax=Ajellomyces
           capsulatus G186AR RepID=C0NSJ2_AJECG
          Length = 594

 Score =  373 bits (957), Expect = e-102,   Method: Composition-based stats.
 Identities = 190/389 (48%), Positives = 248/389 (63%), Gaps = 47/389 (12%)

Query: 7   PYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNIT 66
             FGEFGG YVP+ LM  L +LE                                     
Sbjct: 244 ARFGEFGGQYVPESLMDNLLELEA------------------------------------ 267

Query: 67  AGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALL 126
                     REDL H G+HK N  LGQ LLA+R+GKT IIAETGAGQHGVA+A   A  
Sbjct: 268 ----------REDLNHTGSHKINNALGQVLLARRLGKTRIIAETGAGQHGVATATVCAKF 317

Query: 127 GLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHY 186
           G++C IYMGA+DV RQ+ NVFR++L+GA+V+ V +GS TL+DA NEALR W    +T HY
Sbjct: 318 GMECVIYMGAEDVRRQALNVFRIKLLGAKVVAVEAGSRTLRDAVNEALRAWVVHLDTTHY 377

Query: 187 MLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFIN 246
           ++G+A GPHP+PTIVR  Q +IGEETK Q+ +  GRLPDAV+ACVGGGSNA+GMF  F  
Sbjct: 378 VIGSAIGPHPFPTIVRTLQSVIGEETKEQMQKLTGRLPDAVVACVGGGSNAVGMFYPFTK 437

Query: 247 ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDF 306
           + +V L+GVE GG G +T  H A L HG  G+  G++  ++Q EDGQI +++SISAGLD+
Sbjct: 438 DPSVRLLGVEAGGDGTDTARHSATLSHGSKGVLHGVRTYILQNEDGQIADTHSISAGLDY 497

Query: 307 PSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENP 366
           P VGP+ +      RA +++ TD +AL+ F+ +   EGIIPALESSHA+  A+++ +   
Sbjct: 498 PGVGPELSSWKDQSRAQFIAATDAQALQGFRLITELEGIIPALESSHAVFGAVELAKTMK 557

Query: 367 DKEQLLVVNLSGRGDKDIFTVHDILKARG 395
             E  +V+NLSGRGDKD+ +V D L   G
Sbjct: 558 KGEN-IVLNLSGRGDKDVQSVADALPEIG 585


>UniRef50_Q0RGR3 Tryptophan synthase, beta protein n=2 Tax=Actinomycetales
           RepID=Q0RGR3_FRAAA
          Length = 487

 Score =  367 bits (943), Expect = e-100,   Method: Composition-based stats.
 Identities = 194/389 (49%), Positives = 253/389 (65%), Gaps = 11/389 (2%)

Query: 5   LNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQN 64
           ++  FGEFGG YVP+ L+ A   LE A+  A+ DP F  Q + LL  YAGRPT +T    
Sbjct: 108 VSGRFGEFGGRYVPEALVSACEDLEAAYRDARSDPSFTQQLDHLLSVYAGRPTPVTPANR 167

Query: 65  ITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASA 124
           ++      L LKREDL H G+HK N VLGQ LLA+RMGK  ++AETGAGQHGVA+A   A
Sbjct: 168 LSEELGVHLLLKREDLAHTGSHKINNVLGQGLLAQRMGKKRLLAETGAGQHGVATATIGA 227

Query: 125 LLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETA 184
           LLGL   +YMG  D++RQ+ NVFRM L+GA V+PV SG+ TLKDAC+EALR W    + A
Sbjct: 228 LLGLDVVVYMGEADIQRQALNVFRMELLGATVVPVTSGTRTLKDACSEALRQWVTQVDEA 287

Query: 185 HYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREG-RLPDAVIACVGGGSNAIGMFAD 243
           HY +G+  GPHPYP +VREFQR+IG E +AQ        +PD V ACVGGGSNA G FA 
Sbjct: 288 HYCIGSTMGPHPYPWMVREFQRVIGTEARAQCAGLLRQGVPDVVTACVGGGSNAAGTFAG 347

Query: 244 FINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAG 303
           F++     L+GVE  G        GA +  G  GI  G  + ++Q EDGQ+ E++SISAG
Sbjct: 348 FVDTPA-RLVGVEAAG--------GAAMTDGLPGILHGFYSNILQDEDGQVREAHSISAG 398

Query: 304 LDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMR 363
           LD+P +GP+HA L ++GRA+YV+  D+E + A   L   EGI+PALES+HALA  ++   
Sbjct: 399 LDYPGIGPEHAGLGTSGRAEYVTANDEEVVSAVVRLARAEGILPALESAHALAWIIRAAE 458

Query: 364 ENPDK-EQLLVVNLSGRGDKDIFTVHDIL 391
                    +++ LSGRGDKD   +  ++
Sbjct: 459 SGEIPYGSTVLMTLSGRGDKDAEQLRRLV 487


>UniRef50_B0R332 Tryptophan synthase beta chain n=8 Tax=cellular organisms
           RepID=TRPB_HALS3
          Length = 430

 Score =  364 bits (934), Expect = 3e-99,   Method: Composition-based stats.
 Identities = 193/404 (47%), Positives = 252/404 (62%), Gaps = 27/404 (6%)

Query: 9   FGEFGGMYVPQILMPALRQLEEAFVSAQKDPE--FQAQFNDLLKNYAGRPTALTKCQNIT 66
           FG++GG YVP++LMPA+ +L +A+     D E  F   F   ++++ GRPT LT    ++
Sbjct: 15  FGDYGGQYVPEVLMPAVEELTDAYERYVLDNEDGFVDDFRQRIRSFGGRPTPLTHAPTLS 74

Query: 67  AGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALL 126
                 +YLKREDLLHGGAHK N  LGQ LLAK MGK  I+AETGAGQHG A+A+A A L
Sbjct: 75  QRHGVDVYLKREDLLHGGAHKLNNALGQVLLAKYMGKDRIVAETGAGQHGTATAMACAAL 134

Query: 127 GLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHY 186
            + C IYMG  DV RQ PNVFRMRL  A+V PV  GS TLK+A NE +RDW+ +    HY
Sbjct: 135 EMPCEIYMGRTDVNRQRPNVFRMRLHDADVNPVTVGSGTLKEAINETMRDWATNVADTHY 194

Query: 187 MLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFIN 246
           ++G+  GPHP+P++VR+FQ +I EE +AQ  E+ G LP AVIAC GGGSN +G F  F+ 
Sbjct: 195 VIGSVVGPHPFPSMVRDFQAIISEELRAQSREQLGELPAAVIACAGGGSNTMGAFGAFVG 254

Query: 247 E--------------TNVGLIGVEPGGH------GIETGEHGAPLKHGRVGIYFGMKAPM 286
                           +V L+ VE GG             + A L  G  G+  G +  +
Sbjct: 255 SASLPGAPAGTHEPAPDVDLLAVEAGGSRLGVDDDAGYAPNSASLSTGTEGVLHGARTKL 314

Query: 287 MQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGII 346
           +QTE GQI ES+S+SAGLD+  VGP+ A+L  TGR    ++ DD AL AF  L   EG+I
Sbjct: 315 LQTETGQIVESHSVSAGLDYAGVGPELAHLVDTGRITPTNVDDDAALAAFHRLSRDEGVI 374

Query: 347 PALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDI 390
           PALE+SHA+A   +      D +  +VVN+SGRGDKD+ TV + 
Sbjct: 375 PALETSHAVAALDQY-----DGDGPVVVNVSGRGDKDLDTVIEA 413


>UniRef50_B7G4U3 Tryptophan synthase, beta chain n=3 Tax=cellular organisms
           RepID=B7G4U3_PHATR
          Length = 385

 Score =  353 bits (907), Expect = 5e-96,   Method: Composition-based stats.
 Identities = 167/390 (42%), Positives = 234/390 (60%), Gaps = 21/390 (5%)

Query: 4   LLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQ 63
             + YFGE+GG  +P  L+  + ++ E++    +   FQ + + L K++ GRP+ +   +
Sbjct: 15  SKDGYFGEYGGQQLPPQLVEIMNEISESYEKLIRTDAFQIELDSLNKDFIGRPSPIFYAR 74

Query: 64  NITAGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALA 122
            +T       ++LKREDL H GAHK N  LG+ALLAK MGKT+++AETGAGQHGVA A A
Sbjct: 75  RLTEKIGGARIFLKREDLNHTGAHKINHCLGEALLAKHMGKTKVLAETGAGQHGVALATA 134

Query: 123 SALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYE 182
            AL+G++C I+MG  DVE+++PNV +MR++G ++I V  G+ TLKDA +    ++     
Sbjct: 135 CALIGIECEIHMGQVDVEKEAPNVTKMRILGCKLITVTRGTRTLKDAVDSVFEEYLKDPV 194

Query: 183 TAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFA 242
              Y +G+                      KA      G LPDA++AC GGG NA G+F 
Sbjct: 195 NYFYAIGSVIF-------------------KASWDLEGGALPDAIVACGGGGCNARGIFT 235

Query: 243 DFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISA 302
            F+ +  V LIGVEP G G+ET +H A +  G  G   GM    +Q E G+    YSI++
Sbjct: 236 AFLEDPEVQLIGVEPAGRGLETSDHAATMTLGVKGSIHGMNCYNLQDETGEPLPVYSIAS 295

Query: 303 GLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMM 362
           GLD+P VGPQH  L   GR  YV++TD E L+AF  L   EGIIPALES+HA+A+A K+ 
Sbjct: 296 GLDYPGVGPQHCLLKDIGRTKYVAVTDQECLDAFMQLSRVEGIIPALESAHAVAYATKLA 355

Query: 363 RENPDKEQLLVVNLSGRGDKDIFTVHDILK 392
            E     + ++VNLSGRGDKD   V + L+
Sbjct: 356 VEIGPG-KTILVNLSGRGDKDADFVANRLQ 384


>UniRef50_B8MZR1 Trytophan synthase alpha subunit, putative n=2 Tax=Leotiomyceta
           RepID=B8MZR1_ASPFN
          Length = 641

 Score =  342 bits (877), Expect = 2e-92,   Method: Composition-based stats.
 Identities = 160/390 (41%), Positives = 218/390 (55%), Gaps = 55/390 (14%)

Query: 7   PYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNIT 66
             FG FGG Y P+ L   L +LE  F +A  DP F  ++      Y GRP++L +   +T
Sbjct: 297 GRFGIFGGQYAPEALTTCLAELEAGFQAALDDPTFWEEYRSYY-PYMGRPSSLHQATRLT 355

Query: 67  AGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASAL 125
                  ++LKREDL H G+HK N  L                                 
Sbjct: 356 EHVGGANIWLKREDLNHTGSHKINNAL--------------------------------- 382

Query: 126 LGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAH 185
                               +   R +GA VIPV SGS TL+DA NEA R W    +T H
Sbjct: 383 ------------------GQILIARRLGATVIPVESGSRTLRDAVNEAFRAWIVRLDTTH 424

Query: 186 YMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFI 245
           Y++G+A GPHP+PT+VR FQ +IG ETKAQ+ E  G+ PDAV+ACVGGGSN++GMF  F 
Sbjct: 425 YIIGSAIGPHPFPTMVRTFQSVIGNETKAQMQEL-GKSPDAVVACVGGGSNSVGMFYPFS 483

Query: 246 NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLD 305
            + +V L+GVE  G G++T  H A L  G VG+  G++  ++Q E GQI +++SISAGLD
Sbjct: 484 KDLSVQLVGVEAAGDGLDTDRHSATLTGGSVGVLHGVRTYILQDEHGQISDTHSISAGLD 543

Query: 306 FPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMREN 365
           +P VGP+ A+   + RA ++S TD +A E F+ L   EGIIPALE+SHA+  A++  ++ 
Sbjct: 544 YPGVGPELAHWKESKRATFLSATDAQAFEGFRLLSQLEGIIPALETSHAVWGAIQTAKKL 603

Query: 366 PDKEQLLVVNLSGRGDKDIFTVHDILKARG 395
              +  LV+ LSGRGDKD+ +V D L   G
Sbjct: 604 GPGKD-LVLCLSGRGDKDVQSVADGLPTIG 632


>UniRef50_C0QZH7 Tryptophan synthase beta subunit n=4 Tax=Bacteria
           RepID=C0QZH7_BRAHW
          Length = 417

 Score =  340 bits (873), Expect = 4e-92,   Method: Composition-based stats.
 Identities = 183/379 (48%), Positives = 240/379 (63%), Gaps = 5/379 (1%)

Query: 17  VPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTN-TTLYL 75
           VP+ L   L +LEEAF+    D EF ++  +L  ++ GRPT L   +N++       +Y+
Sbjct: 17  VPEALEKLLIELEEAFLHYINDKEFLSELEELRADFIGRPTPLMYAKNLSEKIGGAKIYV 76

Query: 76  KREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMG 135
           K E L H GAHK N  +GQALLAK+MGK +IIAETGAGQHG+A+A A A LGL+C IYMG
Sbjct: 77  KLEGLAHTGAHKINNSIGQALLAKKMGKKKIIAETGAGQHGLATAAACAKLGLECSIYMG 136

Query: 136 AKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPH 195
             DV+RQ PNV  M L GA V+ V  G   LKDA + AL DW    +  HY+LG+A GP 
Sbjct: 137 EIDVKRQQPNVASMELYGANVVSVTKGGRGLKDAVDMALEDWVKDLKDTHYLLGSAVGPS 196

Query: 196 PYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGV 255
           PYP IVR FQ +IG E   QI E+   +  A+IACVGGGSNAIG F  FI   N  LI V
Sbjct: 197 PYPDIVRTFQSVIGRELDKQIQEKNLNV-KALIACVGGGSNAIGFFEPFIERENPKLIAV 255

Query: 256 EPGGHGIETGEHGAPLK--HGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQH 313
           E GG  +  GE+   ++  + +     G  +  +  E+G+I E+ SISAGLD+P VGPQ 
Sbjct: 256 EAGGISMNLGENAIRMQNPYAKDVAAQGYMSKFILKENGEISETMSISAGLDYPGVGPQL 315

Query: 314 AYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLV 373
           AYL  +GR ++   TD EA+ A K    HEG+I ALES+HA A A++  ++   K+ +++
Sbjct: 316 AYLGESGRIEFTYATDKEAINAVKEFASHEGVIFALESAHAGAKAIEYAKQY-SKDDVII 374

Query: 374 VNLSGRGDKDIFTVHDILK 392
           VN+SGRGDKDIF    I +
Sbjct: 375 VNMSGRGDKDIFITSPIFR 393


>UniRef50_A1DP73 Tryptophan synthase n=4 Tax=Trichocomaceae RepID=A1DP73_NEOFI
          Length = 460

 Score =  324 bits (832), Expect = 2e-87,   Method: Composition-based stats.
 Identities = 143/376 (38%), Positives = 207/376 (55%), Gaps = 17/376 (4%)

Query: 8   YFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITA 67
            FG FGG + P+  M AL++L   F     D  F  +F   L +   RP+ L   +N+T 
Sbjct: 96  RFGTFGGCFAPESQMDALQELTLTFDRLISDYGFWKEF---LSSPGIRPSPLRFAENLTR 152

Query: 68  -GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALL 126
                 ++LKREDL   G+H    ++GQALLA+R+GK E++ E G+ +HG+  A     L
Sbjct: 153 IAGGANIWLKREDLNQHGSHNIRSIVGQALLARRLGKAEVVMECGSARHGIVCAATCTRL 212

Query: 127 GLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVH----SGSATLKDACNEALRDWSGSYE 182
            +KC I MG++D   Q  +V  +R +GA V+       SG  TL+ A NEALR       
Sbjct: 213 NMKCTILMGSRDATDQKDSVDMIRKLGATVLTADMGASSGRGTLRAAVNEALRYSVAHLS 272

Query: 183 TAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREG-RLPDAVIACVGGGSNAIGMF 241
           T ++++    GPHP PTI R FQ ++GEE K Q     G RLPDA+++ VG GS A+GMF
Sbjct: 273 TTYHIMSGPIGPHPLPTITRTFQSILGEEIKTQFGGTSGDRLPDALVSPVGPGSAAVGMF 332

Query: 242 ADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSIS 301
             FI   +V L+G+E            APL HG +G+  G +  ++Q E GQI +S SIS
Sbjct: 333 YPFIEHPSVKLLGIEAA--------DAAPLSHGDIGVLHGCRTYLLQDEHGQILDSGSIS 384

Query: 302 AGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKM 361
             LDFPSVGP+ A+   T R +YV+ TD EAL     L   EGI+    + +A+   +++
Sbjct: 385 PDLDFPSVGPELAHWKETARVEYVTATDAEALRGVDILRSQEGIVSGAMTGYAVERTIRL 444

Query: 362 MRENPDKEQLLVVNLS 377
            RE    + ++++   
Sbjct: 445 ARELGPGKDVVLLVAG 460


>UniRef50_Q1V1Q0 Tryptophan synthase beta chain 1 n=6 Tax=root RepID=Q1V1Q0_PELUB
          Length = 410

 Score =  323 bits (828), Expect = 7e-87,   Method: Composition-based stats.
 Identities = 154/396 (38%), Positives = 227/396 (57%), Gaps = 9/396 (2%)

Query: 5   LNPYFG-EFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQ 63
            N ++G +FGG ++P+ L   +  L E F   + D +F  + +   KNY G PT+  K Q
Sbjct: 15  KNGFWGGKFGGNFIPETLKKPIEDLTELFEKLRYDKKFLKERDYYFKNYIGSPTSFIKLQ 74

Query: 64  NITAGT-NTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALA 122
           N++       +Y K     +GGAHK        L+AK+ GK  ++ +TGAG  G   ++A
Sbjct: 75  NLSDHLSGAQIYAKMVSEANGGAHKIYNATVHCLIAKKAGKKYVVGDTGAGYAGKMLSMA 134

Query: 123 SALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYE 182
           +   GLKC+I+MGAKD++RQ PNV  M+  GAEV+PV+SGS TL DA +E +R W  + +
Sbjct: 135 AKKFGLKCKIFMGAKDIKRQKPNVDAMKKNGAEVVPVYSGSQTLVDAVSECMRYWVSNCD 194

Query: 183 TAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAV--IACVGGGSNAIGM 240
             H  +G+  GP+ +  I       I  E K QI     ++P  +  I CVGGGS+A G 
Sbjct: 195 NTHMCVGSTVGPNIFVKICGWSTAQISRELKVQIQSEFKKMPKKIKLINCVGGGSSAYGF 254

Query: 241 FADFI--NETNVGLIGVEPGGHGIETGEHGAPLKHG-RVGIYFGMKAPMMQTEDGQIEES 297
           +++FI  ++  + LIGVE GG    +  H APL +G ++GI  G  A + Q  +GQI ++
Sbjct: 255 WSEFIDYDKKQIELIGVEAGG-PKNSKLHAAPLTNGAKLGILHGAAAYVCQNSEGQINDT 313

Query: 298 YSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAH 357
            SISAGLD+P V P H +L  T RA Y S TD+ AL A+K +   E I P+LE SHA A 
Sbjct: 314 ASISAGLDYPGVSPIHCFLKDTKRARYTSATDEAALNAYKLVTKLEKINPSLEPSHAFAE 373

Query: 358 ALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
           A+K+  +  +K+ +++VN  G   KD   + + L  
Sbjct: 374 AIKIAPKL-NKDTIIIVNSCGDAKKDRDILKERLGK 408


>UniRef50_B6HPP8 Pc22g00910 protein n=1 Tax=Penicillium chrysogenum Wisconsin
           54-1255 RepID=B6HPP8_PENCW
          Length = 518

 Score =  319 bits (818), Expect = 1e-85,   Method: Composition-based stats.
 Identities = 137/370 (37%), Positives = 220/370 (59%), Gaps = 14/370 (3%)

Query: 9   FGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAG 68
           +G +GG + P+ +M  L +L   F +   DP F  ++    ++   R T L     +T+ 
Sbjct: 147 YGSYGGRFAPESIMGFLYELTSFFEATVSDPSFWEEYATFQRD---RVTPLHMAGKLTSL 203

Query: 69  TN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLG 127
               T++LKRED    G+HKT  + GQ LLA+RMG++EI+ +  + +HG  +A   A LG
Sbjct: 204 AGGATIWLKREDKNEYGSHKTRNITGQLLLARRMGRSEIVTDCASAKHGKVTAAMCARLG 263

Query: 128 LKCRIYMGAKDVERQSPNVFRMRLMGAEVI--PVHSGSATLKDACNEALRDWSGSYETAH 185
           L+C + +GA D   Q  +V  M+ +GA+V+     SG   L+ A  EALR    ++E+A+
Sbjct: 264 LRCVVVIGADDASAQEKDVLEMKSLGAKVLTARAPSGMGGLRAAITEALRYAVCNHESAY 323

Query: 186 YMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFI 245
           Y++G+  GP P PT+ R FQ ++GEE  AQ+ E  GR PDA++  VG GS AIG+F  F+
Sbjct: 324 YLMGSPVGPSPLPTLARTFQSLLGEEVAAQMHEAAGRQPDALVTAVGSGSGAIGLFRPFL 383

Query: 246 NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLD 305
           +++++ L+GVE          + A L  G +G+  G +  ++Q  DGQI +S+SIS  ++
Sbjct: 384 HDSSIRLVGVEAA--------NAAALTDGGLGVLQGARTLLLQNHDGQILDSHSISPDMN 435

Query: 306 FPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMREN 365
             +VGP+ A+   +GR +  + TD  AL+ F+TL  HEGI+P L+SSHA++ AL + RE 
Sbjct: 436 LSTVGPEVAHWKDSGRIEISTATDAVALDGFRTLQQHEGILPGLDSSHAVSKALDLAREL 495

Query: 366 PDKEQLLVVN 375
              + ++++ 
Sbjct: 496 GPGKNVVLMV 505


>UniRef50_C8VGH6 Putative uncharacterized protein n=2 Tax=Emericella nidulans
           RepID=C8VGH6_EMENI
          Length = 443

 Score =  308 bits (790), Expect = 2e-82,   Method: Composition-based stats.
 Identities = 135/385 (35%), Positives = 202/385 (52%), Gaps = 27/385 (7%)

Query: 7   PYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNIT 66
              G FGG + P++ M  L  L   F S   D  F  +F     +   RP+ L    ++T
Sbjct: 73  ARLGRFGGQFAPELQMDLLLDLPSVFHSVLSDNRFWTEF---SASPFLRPSPLHLAHSLT 129

Query: 67  AGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASAL 125
                  ++LKR+DL   G+++T  ++GQ L A+ +GKTEI  E G   HG+  A   A 
Sbjct: 130 KAVGGANIWLKRDDLNPFGSYQTRNIVGQILFAQHIGKTEISMECGFAGHGLFCATMCAR 189

Query: 126 LGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPV-----HSGSATLKDACNEALRDWSGS 180
           + +KC I MGA D+  Q   V  M+ +GA V+ V       GS TL+ A NEALR     
Sbjct: 190 MNMKCTILMGASDIAAQPDAVEEMKQLGATVVSVQCSISDDGSGTLRAATNEALRYSLTR 249

Query: 181 YETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGR-------LPDAVIACVGG 233
             + +++     GPHP PTI R FQ ++G+E K    E  GR        P A+++    
Sbjct: 250 LNSTYHISTGTVGPHPLPTITRTFQSLLGQEIKICSSELPGRGRRKNNFRPSALVST--S 307

Query: 234 GSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQ 293
           G+ A+GMFA FI++  V LI VE            APL HG  G+ +G K  ++Q E+GQ
Sbjct: 308 GAAALGMFAPFISDPAVRLIAVEAA--------DAAPLTHGSPGVMYGCKTLLLQDENGQ 359

Query: 294 IEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSH 353
           I  S+SIS  L+FP  GP+ A+    GR + V+ + +EA+   + LC  EGI+P L +SH
Sbjct: 360 ILPSHSISPDLNFPCAGPELAHWRDLGRLETVTASSEEAVRGLRILCESEGIVPGLATSH 419

Query: 354 ALAHALKMMRENPDKEQLLVVNLSG 378
           A+   +++ R+    + ++++  SG
Sbjct: 420 AVLETVRVARQLGIGKDVVLLI-SG 443


>UniRef50_Q9WZ09 Tryptophan synthase beta chain 2 n=6 Tax=Bacteria RepID=TRPB2_THEMA
          Length = 422

 Score =  280 bits (717), Expect = 6e-74,   Method: Composition-based stats.
 Identities = 110/405 (27%), Positives = 162/405 (40%), Gaps = 51/405 (12%)

Query: 18  PQILMP-ALRQLEEAF-----VSAQKDPEFQAQFNDLLKNY-AGRPTALTKCQNITAGT- 69
           P+   P +  +L   F          +  F      +LK Y   RPT L +   +     
Sbjct: 33  PETKQPISPEKLSVIFPMSLIEQEVSEERFIEIPEPVLKEYAVYRPTPLIRATFLEEYLQ 92

Query: 70  -NTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGL 128
               +Y K E +   G+HK N  + QA   K  G   ++ ETGAGQ G A + A A  GL
Sbjct: 93  TPARIYYKYEGVSPTGSHKPNTAIAQAYYNKIEGVKRLVTETGAGQWGSALSYAGAKFGL 152

Query: 129 KCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS---------------GSATLKDACNEA 173
           + +++M     +++    + M L G +V P  S                  +L  A +EA
Sbjct: 153 EVKVFMVKVSYQQKPMRKYMMNLFGGKVTPSPSEETNFGRKILSEDPDNPGSLGIAISEA 212

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
           L + + S     Y LG+          V   Q +IG E K Q+ E  G  PD ++ C GG
Sbjct: 213 L-EVAVSDPNTKYSLGSVLN------HVLLHQTVIGLEIKKQL-ELIGEKPDILLGCHGG 264

Query: 234 GSNAIGMFADFINET----NVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPM--- 286
           GSN  G    F+ +     ++  +  EP             L  G     FG  A +   
Sbjct: 265 GSNFGGTILPFVPDKLSGRDIRFVACEPAA--------CPSLTKGNYDYDFGDTAGLTPL 316

Query: 287 --MQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEG 344
             M T           + GL +    P  A L   G  +  +   DE  EA K     EG
Sbjct: 317 LKMYTLGKDFIPPKIHAGGLRYHGSAPIIARLVKEGLVEAQAFDQDETFEAAKIFAKLEG 376

Query: 345 IIPALESSHALAHALKMMRENP--DKEQLLVVNLSGRGDKDIFTV 387
           IIPA ES+HA+A A++  ++     KE+++V  LSG G  D+   
Sbjct: 377 IIPAPESAHAIAGAIREAKKAKEEGKERVIVFTLSGHGLLDLTAY 421


>UniRef50_B6YSU5 Tryptophan synthase beta chain n=232 Tax=cellular organisms
           RepID=TRPB_THEON
          Length = 443

 Score =  280 bits (716), Expect = 6e-74,   Method: Composition-based stats.
 Identities = 118/427 (27%), Positives = 173/427 (40%), Gaps = 65/427 (15%)

Query: 17  VPQILMPALR------------------QLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTA 58
           +P+ L P L                   +L +  +S ++  +   +  +L     GRPT 
Sbjct: 21  LPEPLAPPLDPETDEPMESEKLLRIFASELVKQEMSMERYIDIPKKVRELYAK-IGRPTP 79

Query: 59  LTKCQNITAGT--NTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           L +  N+         +Y K E     G+HK N  L QA  AK+ G   ++ ETGAGQ G
Sbjct: 80  LFRATNLEKALETPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETGAGQWG 139

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGS------------- 163
            A +LA AL+G+  R+YM      ++      MRL GAE+ P  S               
Sbjct: 140 TALSLAGALMGINVRVYMARASFYQKPYRKTIMRLYGAEIYPSPSDRTEIGRKFLSEDPN 199

Query: 164 --ATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREG 221
               L  A +EA+ D     E A Y LG+          V   Q +IG E K Q+ E   
Sbjct: 200 HPGGLGIAISEAIEDVL-RDEKARYALGSVLN------HVLMHQTVIGLEAKEQMKEF-- 250

Query: 222 RLPDAVIACVGGGSNAIGMFADFINET-----NVGLIGVEPGGHGIETGEHGAPLKHGRV 276
             PD +I CVGGGSN  G+   F+ +      +   I VEP             +  G  
Sbjct: 251 EDPDVIIGCVGGGSNFAGLAYPFVKDRLDGKADYEFIAVEPRA--------APSMTRGVY 302

Query: 277 GIYFGM-----KAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDE 331
              +G          M T           + GL +  + P  + L + G    V+    E
Sbjct: 303 TYDYGDSGGLTPKMKMHTLGHTYYVPPIHAGGLRYHGLAPTLSILINHGIVRPVAYHQTE 362

Query: 332 ALEAFKTLCLHEGIIPALESSHALAHALK--MMRENPDKEQLLVVNLSGRGDKDIFTVHD 389
             EA +     EGI+PA ES+HA+  A+   +  +   KE++++ NLSG G  D+    D
Sbjct: 363 VFEAARLFAKTEGIVPAPESAHAVKAAIDRALKAKEEGKEEVILFNLSGHGLLDLKGYED 422

Query: 390 ILKARGE 396
            L  + E
Sbjct: 423 FLDGKLE 429


>UniRef50_D2L2T8 Pyridoxal-phosphate dependent TrpB-like enzyme n=2 Tax=Bacteria
           RepID=D2L2T8_9DELT
          Length = 447

 Score =  272 bits (696), Expect = 1e-71,   Method: Composition-based stats.
 Identities = 103/412 (25%), Positives = 161/412 (39%), Gaps = 54/412 (13%)

Query: 18  PQILMP-ALRQLEEAFVSAQKDPE--------FQAQFNDLLKNYAGRPTALTKCQNITAG 68
           PQ   P +  QLE  F  A  + E              D+ + Y  RPT L + + +   
Sbjct: 33  PQTKQPVSPEQLEAIFPKAVIEQELSTERWLPIPEPVRDIYRLY--RPTPLVRAKRLEEA 90

Query: 69  TN--TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALL 126
                 ++ K E +   G+HK N  + QA   K  G   I  ETGAGQ G A + A ++ 
Sbjct: 91  LGVKCKIFYKNESVSPAGSHKPNTAIPQAYYNKLEGVRRISTETGAGQWGTALSFACSMF 150

Query: 127 GLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSG---------------SATLKDACN 171
           G+ C +YM      ++      +   G E+    S                S +L  A +
Sbjct: 151 GMACTVYMVKVSYNQKPYRRILINAYGGEIFASPSENTKTGRAVLASDPDCSGSLGLAIS 210

Query: 172 EALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACV 231
           EA+ D + ++    Y LG+          V   Q +IG E + Q+    G  PD ++ CV
Sbjct: 211 EAVED-AATHADTKYALGSVLN------HVLHHQTIIGLEVEKQL-AAIGEKPDYLVGCV 262

Query: 232 GGGSNAIGMFADFINET----NVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPM- 286
           GGGSN  G+   F+        +  I VEP             L  G+    +G  A + 
Sbjct: 263 GGGSNFAGLVLPFLPRKLSGEAIRFIAVEPKA--------CPTLTRGQFRYDYGDVAQLT 314

Query: 287 ----MQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLH 342
               M T       +   + GL +    P    L + G  D  +    E  +A +     
Sbjct: 315 PLLKMHTLGHAFMPAPIHAGGLRYHGGAPIVCNLANEGLIDATAYFQTECFDAARLFLRT 374

Query: 343 EGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKAR 394
           EG +PA E+SHA+  A++  ++    E  +V   SG G  D+ +    L+ +
Sbjct: 375 EGFLPAPETSHAIKGAIETAKKAKPGEN-VVFLYSGHGLLDLASYDAFLQGK 425


>UniRef50_A8F8F7 Tryptophan synthase beta chain n=12 Tax=cellular organisms
           RepID=TRPB_THELT
          Length = 422

 Score =  271 bits (692), Expect = 4e-71,   Method: Composition-based stats.
 Identities = 105/401 (26%), Positives = 156/401 (38%), Gaps = 44/401 (10%)

Query: 15  MYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGT--NTT 72
             +   ++ A+  +           E       L +    RPT L +   +         
Sbjct: 37  QPISPDMLSAIFPMPLIEQEVTDKREIPIPEPVLEEYAVFRPTPLFRATYLEEFLQTPAR 96

Query: 73  LYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRI 132
           +Y K E     G+HKTN  L QA   K  G   ++ ETGAGQ G A   + A  GLK  +
Sbjct: 97  IYYKYEGASPTGSHKTNTALAQAYYNKISGTERLVTETGAGQWGSALCYSGAKFGLKVNV 156

Query: 133 YMGAKDVERQSPNVFRMRLMGAEVIPVHS---------------GSATLKDACNEALRDW 177
           +M     E++    + MRL   +V+P  S                  +L  A +EA+ + 
Sbjct: 157 FMVKISYEQKPMRKYLMRLFDGDVVPSPSEKTSFGKSILASNSENPGSLGIAISEAI-EI 215

Query: 178 SGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNA 237
           + S     Y LG+          V   Q +IG E K Q+ E  G  PD ++ C GGGSN 
Sbjct: 216 TLSDSRTKYSLGSVLN------HVLLHQTVIGLELKKQL-EVLGEKPDVILGCHGGGSNF 268

Query: 238 IGMFADFINE----TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKA-----PMMQ 288
            G    FI +      +  +  EP             L  GR    +G  A       M 
Sbjct: 269 GGTVLPFIPDKLSGKEIKFVACEPTA--------CPSLTRGRYDYDYGDTAGMTPLLKMY 320

Query: 289 TEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPA 348
           T           + GL +    P  + L   G  + V+   DE   A K     EGI+PA
Sbjct: 321 TLGKDFIPPKIHAGGLRYHGAAPIISRLVKEGLIEAVAFDQDEIFSAAKLFAKLEGIVPA 380

Query: 349 LESSHALAHALKMMRENPDKE--QLLVVNLSGRGDKDIFTV 387
            ESS+A+A A++  ++  +    +++V NLSG G  D+   
Sbjct: 381 PESSYAIAGAIREAKKAKEHNIPRVVVFNLSGHGLFDLTAY 421


>UniRef50_Q9Y8T5 Tryptophan synthase beta chain 1 n=10 Tax=Thermoprotei
           RepID=TRPB1_AERPE
          Length = 427

 Score =  266 bits (681), Expect = 8e-70,   Method: Composition-based stats.
 Identities = 115/401 (28%), Positives = 165/401 (41%), Gaps = 42/401 (10%)

Query: 20  ILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTT----LYL 75
           IL   L + E         P    +         GRPT L + + +           +Y 
Sbjct: 40  ILPSRLIEDEYILARWVDIPGEVRKALAR----IGRPTPLIRAEGLEKVLGVKGRVRIYY 95

Query: 76  KREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMG 135
           K E +L  G+HK N  + QA  AK  G  EI+ ETGAGQ G+A++ A+AL+GLK  ++M 
Sbjct: 96  KSEAVLPTGSHKINTAIAQAYYAKLDGAKEIVTETGAGQWGLAASTAAALMGLKATVFMT 155

Query: 136 AKDVERQSPNVFRMRLMGAEVIPVHS----------------GSATLKDACNEALRDWSG 179
           A   + +      M   GA VI   S                   +L  A  EA+     
Sbjct: 156 ASSFKSKIQRRLLMEAQGARVISSPSKLTDTGREALEEYGSTHPGSLGLAIAEAVEYTLE 215

Query: 180 SYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIG 239
           S +   Y+ G+          V   Q +IG E   Q+ E     PD V+ACVGGGSN  G
Sbjct: 216 SGDR-RYLPGSVLE------AVLMHQTVIGLEALDQLPEE----PDVVVACVGGGSNFGG 264

Query: 240 MFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPM-----MQTEDGQI 294
                I    +   G E              L  G         + +     M T   + 
Sbjct: 265 FTYPMIGA-RLRGEGFEKTRFIAAESTAAPKLTRGEYRYDGLDSSLILPLAKMYTLGHRY 323

Query: 295 EESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHA 354
               S +AGL +  V P  + L   G  +  +I  +EAL +   +   EG++PA ESSHA
Sbjct: 324 TPPPSHAAGLRYHGVSPSLSILRRLGLVEAEAIPQEEALASILLMARSEGVVPAPESSHA 383

Query: 355 LAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKARG 395
           +A A ++ R+ PD   ++  NLSG G  D+  +   L+ RG
Sbjct: 384 VALAARIARKLPDGS-VVAFNLSGHGLLDLDALQKALEIRG 423


>UniRef50_C7N0P7 Pyridoxal-phosphate dependent TrpB-like enzyme n=8 Tax=Bacteria
           RepID=C7N0P7_SLAHD
          Length = 470

 Score =  255 bits (652), Expect = 2e-66,   Method: Composition-based stats.
 Identities = 110/405 (27%), Positives = 162/405 (40%), Gaps = 50/405 (12%)

Query: 19  QILMPALRQ--LEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTN--TTLY 74
           + L P      + +   +  +  +      ++ K Y  RP+ L +  N+         +Y
Sbjct: 46  EHLAPVFADELVRQELDNETRYVDIPEGIREMYKVY--RPSPLCRAYNLEKALGTPAKIY 103

Query: 75  LKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYM 134
            K E     G+HK N  L QA  A   G T I  ETGAGQ G A + A+A  GL C ++M
Sbjct: 104 YKFEGNNTSGSHKLNSALAQAYYAHEQGLTTITTETGAGQWGTALSEAAAHYGLNCDVFM 163

Query: 135 GAKDVERQSPNVFRMRLMGAEVIPVHSG---------------SATLKDACNEALRDWSG 179
                E++      M+  GA+V P  S                S +L  A +EA+     
Sbjct: 164 VRASYEQKPFRRSVMQTFGAQVTPSPSQETEIGRKMYADEANRSGSLGTAISEAVERALH 223

Query: 180 SYET-AHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAI 238
             E    Y LG+          V   Q +IG E+ A   E  G  PD VI C GGGSN  
Sbjct: 224 VPENKGRYQLGSVLNQ------VVLHQSIIGLESLAAFDEL-GEYPDVVIGCAGGGSNLG 276

Query: 239 GMFADFINE------TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYF---GMKAPM--M 287
           G+ A F+ +       +   I VEP             L  GR    F   G   P+  M
Sbjct: 277 GLIAPFMRDKLTGEKPDTRFIAVEPA--------SCPSLTRGRYAYDFADTGQTCPLVKM 328

Query: 288 QTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIP 347
            T       S   + GL +  + P  + L   G  D VS+   +   A +     E I+P
Sbjct: 329 YTLGNGFIPSPDHAGGLRYHGMSPIISKLKHDGYLDAVSVKQTDVFAAAEEFAKLETILP 388

Query: 348 ALESSHALAHALKMMRENP--DKEQLLVVNLSGRGDKDIFTVHDI 390
           A ES+HA+  A++  R+     +E++++  L+G G  D+      
Sbjct: 389 APESAHAICVAMEEARKCAETGEEKVILFGLTGTGYFDMTAYEAF 433


>UniRef50_Q13AA2 Tryptophan synthase, beta chain-like n=7 Tax=Bacteria
           RepID=Q13AA2_RHOPS
          Length = 454

 Score =  253 bits (646), Expect = 8e-66,   Method: Composition-based stats.
 Identities = 96/400 (24%), Positives = 155/400 (38%), Gaps = 39/400 (9%)

Query: 19  QILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTN--TTLYLK 76
           + L P   +L    V+  +  +  A   D+ +    RP+ L + + +         +Y K
Sbjct: 47  EPLFP--MELILQEVATDRYIDIPAPVRDVFR--MWRPSPLVRARRLEQALGTPAKIYYK 102

Query: 77  REDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGA 136
            E +   G+HK N  + QA   K+ G  ++  ETGAGQ G + A A +L GL   ++   
Sbjct: 103 YEGVSPAGSHKPNTAVPQAWYNKQAGIKKLSTETGAGQWGSSLAFAGSLFGLDVLVFQVR 162

Query: 137 KDVERQSPNVFRMRLMGAEVIPVHSG---------------SATLKDACNEALRDWSGSY 181
              +++      M   GA  I   S                  +L  A +EA+ + +   
Sbjct: 163 ISYDQKPYRRALMETYGARCIASPSNETESGRSILAQTPDSPGSLGIAISEAV-EVAAKN 221

Query: 182 ETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMF 241
               Y LG+          V   Q +IGEE   Q  E  G  PD +I C GGGSN  G+ 
Sbjct: 222 PDIKYALGSVLN------HVMLHQTIIGEEAIKQC-EMAGDDPDVIIGCAGGGSNFAGLA 274

Query: 242 ADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPM-----MQTEDGQIEE 296
             FI      L G                L  G+    FG  + +     M T       
Sbjct: 275 FPFIGL---QLRGGRRRRIIAVEPAACPSLTRGKYAYDFGDTSHLTPLMKMHTLGSTFMP 331

Query: 297 SYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALA 356
               + GL +  +G   ++    G  +  +    +  EA      +EGI+PA ES+HA+ 
Sbjct: 332 PGFHAGGLRYHGMGAMVSHAYELGLIEARAYHQVKCFEAGVQFARNEGIVPAPESTHAVR 391

Query: 357 HALKMMR--ENPDKEQLLVVNLSGRGDKDIFTVHDILKAR 394
            A+      +   K + ++ NLSG G  D+ +  +  + +
Sbjct: 392 CAIDEALRCKEEGKSETILFNLSGHGHFDMQSYINYFEGK 431


>UniRef50_B1KQQ7 Pyridoxal-5'-phosphate-dependent protein beta subunit n=2
           Tax=Proteobacteria RepID=B1KQQ7_SHEWM
          Length = 440

 Score =  250 bits (638), Expect = 9e-65,   Method: Composition-based stats.
 Identities = 99/393 (25%), Positives = 164/393 (41%), Gaps = 37/393 (9%)

Query: 22  MPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTN--TTLYLKRED 79
              L +      +     +   +  + L    GRPT L +  ++         +Y KRED
Sbjct: 60  PKILLEQNAPKENWI---DIPEEVINKLIM-CGRPTPLRRALSLEKHLKTPARIYFKRED 115

Query: 80  LLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDV 139
            +  G+ K +  + QA  AK+ G+  +I+ETGAGQ G++ AL S + GL  RI+M    +
Sbjct: 116 TMATGSFKLSTAVAQAYYAKQEGREILISETGAGQWGMSVALVSQMFGLDARIFMARCSL 175

Query: 140 ERQSPNVFRMRLMGAEVIP---------------VHSGSATLKDACNEALRDWSGSYETA 184
           E++      M+++G EV P                     ++  A +EA+       E A
Sbjct: 176 EQKPYRQHYMKMLGCEVYPSPSTKTECGKELLLQTPGHPGSIGSAISEAI-------ENA 228

Query: 185 HYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADF 244
               G+A         V   Q ++G E K Q+        D ++ACV GGSN  G    F
Sbjct: 229 LDTPGSAYLSGSNVNHVHLHQTLLGLEVKQQLSMAGESNVDHLVACVSGGSNLCGFMMPF 288

Query: 245 INETNVG----LIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSI 300
           + E N G    ++GVE       T       ++ R  +       +  +       +   
Sbjct: 289 LPEKNSGAKIDMLGVESTASPRLT---QGTYEYCRSDVAGYTPEVLSHSMGESYIPAPVH 345

Query: 301 SAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALK 360
             GL   +  P  + L   G     ++ +  A +A + +   EGI+ A ESSHA+A A+ 
Sbjct: 346 VGGLRNHNSSPLVSLLCREGILRAEALDEFNAFKAGQIMLKTEGILVAPESSHAVAAAID 405

Query: 361 MMRE--NPDKEQLLVVNLSGRGDKDIFTVHDIL 391
           +  +    +KE ++V   SG G  D+   +D+L
Sbjct: 406 LAEKARIENKESVIVFLASGNGFLDLQGYNDVL 438


>UniRef50_C7GZ56 Tryptophan synthase beta chain 2 n=3 Tax=Bacteria
           RepID=C7GZ56_9FIRM
          Length = 461

 Score =  247 bits (630), Expect = 7e-64,   Method: Composition-based stats.
 Identities = 101/398 (25%), Positives = 152/398 (38%), Gaps = 49/398 (12%)

Query: 29  EEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTN--TTLYLKREDLLHGGAH 86
           ++         +   +  DL + Y  RP+ L +  ++    +    +Y K E     G+H
Sbjct: 60  KQELNDTDTYIDIPEKLMDLYRQY--RPSPLCRAYHLEKALDTPAKIYYKFEGNNTAGSH 117

Query: 87  KTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNV 146
           K N  + Q   AK  G   +  ETGAGQ G A A A    GL   +YM     E +    
Sbjct: 118 KLNSSIPQVYYAKEQGLKGVTTETGAGQWGTALAEACGFFGLDLIVYMVRVSYEGKPFRR 177

Query: 147 FRMRLMGAEVIPVHSG---------------SATLKDACNEALRDWSGSYETAHYMLGTA 191
             +   G +VIP  S                  +L  A +EA+ + +       Y LG+ 
Sbjct: 178 NIIETFGGKVIPSPSDTTESGRAILKMDPDSPGSLGTAISEAV-ETASKDPGFRYTLGSV 236

Query: 192 AGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINET--- 248
                    V   Q +IG E+   + +     PD VI C GGGSN  G+ A F  +    
Sbjct: 237 LNQ------VALHQSIIGMESYKAM-QIYDEYPDIVIGCAGGGSNLAGLIAPFARDKIQG 289

Query: 249 --NVGLIGVEPGGHGIETGEHGAPLKHGRVGIYF---GMKAPM--MQTEDGQIEESYSIS 301
             N  L+ VEP             L  G     +   G   PM  M T   +     + +
Sbjct: 290 EHNPELLAVEP--------SSCPTLTRGSYLYDYCDAGKITPMAKMYTLGNEFMPPATHA 341

Query: 302 AGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKM 361
            GL +  + P  + L   G     S    E  EA K    +E I+PA ESSHA+  A+  
Sbjct: 342 GGLRYHGMSPIVSKLYHDGYMKAKSYGQTEIFEAAKFFAKYETILPAPESSHAIKGAIDE 401

Query: 362 MRENPDKE--QLLVVNLSGRGDKDIFTVHDILKARGEI 397
             +  ++   + ++  L+G G  D+         RGE+
Sbjct: 402 AIKCREENTKKTILFGLTGTGFFDMKAYDQF--NRGEM 437


>UniRef50_Q970N1 Tryptophan synthase beta chain 2 n=16 Tax=Archaea RepID=TRPB2_SULTO
          Length = 431

 Score =  246 bits (627), Expect = 2e-63,   Method: Composition-based stats.
 Identities = 98/402 (24%), Positives = 158/402 (39%), Gaps = 39/402 (9%)

Query: 19  QILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTN--TTLYLK 76
           Q+L   + +LE +     K PE        L+   GRPT + + + +         +Y+K
Sbjct: 45  QVLPSKVLELEFSKERYIKIPE--EVLQRYLQ--VGRPTPIIRARKLEEYLGGYIKIYMK 100

Query: 77  REDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGA 136
            E   + G+HK N  L     AK      +  ETGAGQ G A ALASAL  ++  I+M  
Sbjct: 101 MESHTYTGSHKINSALAHVYFAKLDNAKFVSTETGAGQWGSAVALASALFNIQAHIFMVR 160

Query: 137 KDVERQSPNVFRMRLMGAEVIPVHSG---------------SATLKDACNEALRDWSGSY 181
                +    + M++  A+V P  S                  +L  A +EA+     + 
Sbjct: 161 TSYYAKPYRRYLMQMYNAQVHPSPSEFTRYGREVLAKDPNTPGSLGIAISEAVYYALEN- 219

Query: 182 ETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMF 241
               Y++G+             F+ + G E K Q+ E  G  PD +I  VGGGSN   + 
Sbjct: 220 -GGKYVVGSVVNSD------ILFKTIAGMEAKKQM-EMIGEDPDYIIGVVGGGSNYAALA 271

Query: 242 ADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPM-----MQTEDGQIEE 296
             F+ E      G     +          +  G     +   A +     M T       
Sbjct: 272 YPFLGEELRK--GKVRRKYIASGAIEVPKMTKGVYKYDYPDTAKILPMLKMYTIGSDFIP 329

Query: 297 SYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALA 356
           +   + GL + +V P  + L   G       + +EA    K     EG +PA E+SHAL 
Sbjct: 330 APVYAGGLRYHAVAPTLSLLMYKGIVQARDYSQEEAFSWAKLFSQIEGWVPAPETSHALP 389

Query: 357 HALKMMRENP--DKEQLLVVNLSGRGDKDIFTVHDILKARGE 396
              +++ E     +++ ++++ SG G  D+    D+L    E
Sbjct: 390 ILKEIVEEAKKSGEKKTVLISFSGHGLLDLANYADVLGFNKE 431


>UniRef50_Q58860 Probable threonine synthase n=38 Tax=Archaea RepID=THRC_METJA
          Length = 405

 Score =  235 bits (600), Expect = 2e-60,   Method: Composition-based stats.
 Identities = 78/366 (21%), Positives = 135/366 (36%), Gaps = 29/366 (7%)

Query: 24  ALRQLEEAFVSAQKDPEFQAQFNDL-LKNYAGRPTALTKCQNITAGTNTT-LYLKREDLL 81
           +  +L +  +   +  E+    ++  + +     T L +C N+        LY+K E   
Sbjct: 41  SEEKLRKREIGVWRYLEYLPVKDESKIVSLCEGGTPLYRCNNLEKELGIKELYVKNEGAN 100

Query: 82  HGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVER 141
             G+ K   +      A  +G  E++     G    + A  SA  G KC + +    V  
Sbjct: 101 PTGSFKDRGMTVGVTRANELGV-EVVGCASTGNTSASLAAYSARSGKKCIVLLPEGKVA- 158

Query: 142 QSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIV 201
               + +    GA+VI V        D   +  ++         Y+L +   P       
Sbjct: 159 -LGKLAQAMFYGAKVIQVKGNFDDALDMVKQLAKE------KLIYLLNS-INPFR----- 205

Query: 202 REFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHG 261
            E Q+ I  E   Q+     ++PD VI  VG   N   ++  F      G+I   P   G
Sbjct: 206 LEGQKTIAFEICDQL---NWQVPDRVIVPVGNAGNISAIWKGFKEFEITGIIDELPKMTG 262

Query: 262 IETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGR 321
           I+       ++  R       K  +       I  +  I   ++ P      A  +S G 
Sbjct: 263 IQADGAKPIVEAFRK----RAKDIIPYKNPETIATAIRIGNPVNAPK--ALDAIYSSGGY 316

Query: 322 ADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDK-EQLLVVNLSGRG 380
           A+   +TD+E +EA K L   EGI     S+ ++A   K++ E     ++ +V   +G G
Sbjct: 317 AEA--VTDEEIVEAQKLLARKEGIFVEPASASSIAGLKKLLEEGIIDRDERIVCITTGHG 374

Query: 381 DKDIFT 386
            KD   
Sbjct: 375 LKDPDA 380


>UniRef50_C2BGX3 Threonine ammonia-lyase n=3 Tax=Anaerococcus RepID=C2BGX3_9FIRM
          Length = 394

 Score =  234 bits (597), Expect = 4e-60,   Method: Composition-based stats.
 Identities = 75/354 (21%), Positives = 125/354 (35%), Gaps = 44/354 (12%)

Query: 41  FQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKR 100
           F  +      +    PT L   +  +  +N  +Y+K E+L   G+ K      +     +
Sbjct: 2   FDFKKAKERVDEVINPTHLIYSEVFSDSSNNNVYIKPENLQKTGSFKLRGAYNKLSKLDK 61

Query: 101 MGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVH 160
               + I    AG H    A ++  LG+K  I M       +   V      GAEV+   
Sbjct: 62  ESADKGIITASAGNHAQGVAFSAQKLGMKAVICMPEHTPMIK---VDGTLKYGAEVVL-- 116

Query: 161 SGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILERE 220
              A+  +  + AL+             G    P      V E Q  IG E   ++    
Sbjct: 117 -HGASFDECKDHALKLAEEK--------GYTFIPPFDDLDVIEGQGTIGLEIVEEL---- 163

Query: 221 GRLPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIY 279
            +  D V+  VGGG    G+          + +IGVEP             +K G +   
Sbjct: 164 -KYVDYVLVPVGGGGLISGVAKCLKQISPLIKVIGVEP----YSARSMKEAVKLGHIVTL 218

Query: 280 FGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTL 339
            G+                +I+ G    +VG  +  +      D++++TD+E L AF  L
Sbjct: 219 EGVD---------------TIADGTAVATVGKLNYEICKDNVDDWITVTDEEILMAFIKL 263

Query: 340 CLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
                +I        LA   K+     +K  + VV  SG G+ D+  +  ++  
Sbjct: 264 IEKHKLIAEPSGILPLAALDKL--NFFNKNVVCVV--SG-GNIDMSFISQLIDR 312


>UniRef50_C7DG26 Pyridoxal-phosphate dependent TrpB-like enzyme n=1 Tax=Candidatus
           Micrarchaeum acidiphilum ARMAN-2 RepID=C7DG26_9EURY
          Length = 446

 Score =  234 bits (597), Expect = 5e-60,   Method: Composition-based stats.
 Identities = 97/396 (24%), Positives = 157/396 (39%), Gaps = 39/396 (9%)

Query: 20  ILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTN--TTLYLKR 77
           +L   + +LE +       P    +  D  K    RPT + + + + A       +Y+K 
Sbjct: 56  VLPKGVLELEFSDKDHIPIP---EEIRDKFKM-VNRPTPIIRARQLEAHFGNKVKIYMKM 111

Query: 78  EDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAK 137
           E   + G+HK N  + QA  AK  G   +  ETGAGQ G A ALA++L GL+ +I+M   
Sbjct: 112 EGFTYVGSHKINSSIPQAYYAKADGAKFVTTETGAGQWGSAVALAASLFGLESKIFMVKV 171

Query: 138 DVERQSPNVFRMRLMGAEVIPVHS---------------GSATLKDACNEALRDWSGSYE 182
               +    + M + G EV P  S                  +L  A  +A+        
Sbjct: 172 SYAGKPYRRYLMNMFGGEVHPSPSELTGFGRGILRKEPDSPGSLGMAITDAVEYAKEH-- 229

Query: 183 TAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFA 242
              Y++G+             F+ + G E K Q+ E  G  PD VI CVGGGSN  G+  
Sbjct: 230 GGKYVVGSVVNSD------LMFKSIAGLEAKKQM-ESIGEDPDYVIGCVGGGSNYAGLAY 282

Query: 243 DFINET-NVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPM-----MQTEDGQIEE 296
            F+ E    G I       G         +  G+    +     +     M T       
Sbjct: 283 PFLEEELKAGKIRRRYIAAG---SAEIPKMTKGKYEYDYPDTGKVLPQLKMYTVGHDFVP 339

Query: 297 SYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALA 356
               + GL + +V P  + L S G  +      +E+    K     EG +PA E+SH+  
Sbjct: 340 PPIYAGGLRYHAVAPSLSLLMSKGIVEARDYDQNESFRYAKLYSKIEGYVPAPETSHSFP 399

Query: 357 HALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILK 392
              ++ ++   K+ +++++ SG G  D+    +   
Sbjct: 400 IIEEIAKKAGSKKPVVLMSFSGNGMLDLANYAEAFG 435


>UniRef50_B6A2K1 Pyridoxal-5'-phosphate-dependent protein beta subunit n=8
           Tax=Proteobacteria RepID=B6A2K1_RHILW
          Length = 323

 Score =  230 bits (586), Expect = 9e-59,   Method: Composition-based stats.
 Identities = 67/353 (18%), Positives = 119/353 (33%), Gaps = 41/353 (11%)

Query: 42  QAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRM 101
             +  + LK    R T L + + I       LYLK E L   GA K    L + L   R 
Sbjct: 10  IREAQERLK-PHIRHTPLLRAEKIEKAVGCQLYLKPETLQITGAFKIRGALNKVLSLPRE 68

Query: 102 GKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS 161
                +  + +G H    + A+ +LG+K  + +     + +  N    R +GAEVI    
Sbjct: 69  EIANGVIASSSGNHAQGLSYAARILGVKVILVLPVTTPKIKIANT---RALGAEVILFDG 125

Query: 162 GSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREG 221
            +A       E   +        +  +     P     +V   Q  IG E    + +   
Sbjct: 126 DTAARWKKVYEIAEE------NNYATIHGFEDP-----LVMAGQGTIGCEILEDLDD--- 171

Query: 222 RLPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYF 280
              D VI  VGGG    G+       + +V ++G EP                       
Sbjct: 172 --VDTVIVPVGGGGLISGIATAIKETKPSVRVVGAEPALTPKYFHSR------------- 216

Query: 281 GMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLC 340
                 +  E   +    +I+ GL     G     +      + V + D++ +   ++L 
Sbjct: 217 ------INKERTSLPLKNTIADGLRISVPGQNPYPIIEKYVDEIVLVDDEDIIAGMRSLA 270

Query: 341 LHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDK-DIFTVHDILK 392
               +I    +S  +   L    +    E++  V   G  D  D+  ++ + +
Sbjct: 271 RDAKLITEPAASIGIGALLAGSIKVRPDEKVCAVLTGGNWDLCDLAEIYKVFE 323


>UniRef50_B6YXA7 Hypothetical threonine synthase (TS) n=1 Tax=Thermococcus
           onnurineus NA1 RepID=B6YXA7_THEON
          Length = 389

 Score =  227 bits (579), Expect = 5e-58,   Method: Composition-based stats.
 Identities = 71/337 (21%), Positives = 119/337 (35%), Gaps = 31/337 (9%)

Query: 57  TALTKCQNITAGTNT-TLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           T L + + +        LY+K E     GA K      +   A      ++I     G  
Sbjct: 80  TRLYRAKRLEEKIGISKLYIKNEGENPTGAFKDRGSSVEITKALEFHAQKVIVA-STGNM 138

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
             + +   A  GLK  I +     E +     + ++ GA V        T  +A  EA R
Sbjct: 139 AASISAYGAKAGLKVTIVVPEGTPEGKLV---QAKMYGANV---EVFGKTYDEALAEAER 192

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
                 E  +Y+ G             E Q+  G E   Q+      +PD ++  +G G+
Sbjct: 193 RA---LEDGYYLTG-------NYHYRVEGQKTTGFEIIDQLH---FNVPDWIVVPIGAGT 239

Query: 236 NAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIE 295
           +   ++        +GLI   P   G++          G   I    K      +  +  
Sbjct: 240 HLRAIWKGLKEFYRIGLISELPRIAGVQ--------IEGYDSIVRAWKTSKPIEKITKKV 291

Query: 296 ESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHAL 355
            + + +  +  P  G               ++T++E   A   L   EG+     S+ +L
Sbjct: 292 PTIASAIAVKAPVDGENVLKAVKESNGYLDTVTNEETAAAGLLLGR-EGLFVEPSSATSL 350

Query: 356 AHALKMMREN-PDKEQLLVVNLSGRGDKDIFTVHDIL 391
           A A KM  E   DK + +V+  +G G KDI T   +L
Sbjct: 351 ALAQKMREEGIIDKGESVVIIATGHGLKDINTWSKVL 387


>UniRef50_Q54HH2 Probable serine racemase n=1 Tax=Dictyostelium discoideum
           RepID=SRR_DICDI
          Length = 324

 Score =  226 bits (576), Expect = 1e-57,   Method: Composition-based stats.
 Identities = 68/352 (19%), Positives = 118/352 (33%), Gaps = 42/352 (11%)

Query: 42  QAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRM 101
             + +  ++ Y  + T +     I       LY K E+L   G+ K              
Sbjct: 12  IKEAHKRIEKYIHK-TPVLTNSTINELAGKELYFKCENLQKTGSFKMRGACNAIFSLDEE 70

Query: 102 GKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS 161
             ++ +    +G HG A + AS +  +KC + +       +      +   GA V     
Sbjct: 71  ELSKGVVTHSSGNHGQALSYASKVRCVKCYVVVPEDAPSVKL---NAICGYGATVTKCK- 126

Query: 162 GSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTI-VREFQRMIGEETKAQILERE 220
                  A  EA    +      H    +    HP+  + V   Q     E   Q+    
Sbjct: 127 -------ATLEARESNTKQLIEQH----SCKLIHPFDNLQVIAGQGTASLELMEQV---- 171

Query: 221 GRLPDAVIACVGGGSNAIGMF-ADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIY 279
               DA+I  VGGG    G          N+ +   EP G      +    L  G +   
Sbjct: 172 -ENLDAIITPVGGGGLLSGTCITAKSLNPNIKVFAAEPLG----ADDTYRSLLSGEI--- 223

Query: 280 FGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTL 339
                     +     +  +I+ GL   +VG     +        + +T+DE   A K +
Sbjct: 224 ----------QKHTPGKPNTIADGL-LTTVGSLTFPIIKENCDGVILVTEDEIKYAMKLV 272

Query: 340 CLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDIL 391
                II    S+  LA  LK   ++    + + + +SG G+ D+ ++  IL
Sbjct: 273 WERMKIIIEPSSATTLAAILKQEFKDKKDIKKVGIIISG-GNVDLSSISKIL 323


>UniRef50_B7G9B5 L-threonine ammonia-lyase n=3 Tax=cellular organisms
           RepID=B7G9B5_PHATR
          Length = 606

 Score =  224 bits (570), Expect = 7e-57,   Method: Composition-based stats.
 Identities = 73/354 (20%), Positives = 120/354 (33%), Gaps = 35/354 (9%)

Query: 41  FQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKR 100
           + ++  +         + L   +N++A    T+ LKRED     + K      +     R
Sbjct: 90  YLSKILNARVYDVAIESELQHAKNLSAHLKNTVLLKREDTQPVFSFKIRGAYNKMSHLSR 149

Query: 101 MGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVH 160
               + +    AG H    AL++ +LG +  I M       +   V  +R+ G   + V 
Sbjct: 150 DLLDKGVVCCSAGNHAQGVALSAKMLGCRAVIVMPLATPAIK---VNAVRIHGGPSVEVR 206

Query: 161 SGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILERE 220
                  +A  EA R              T   P   P +V   Q  IG E    + E  
Sbjct: 207 LFGNNYDEAATEAKRLQLEDG-------MTFVHPFDDP-LVIAGQGTIGMEI---LKECV 255

Query: 221 GRLPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIY 279
            R  DA+  C GGG    G+ A        V +IGVE      +     A L+ G++   
Sbjct: 256 SRPLDAIFVCCGGGGMLAGIAAYVKRVRPTVKVIGVEAA----DAAGMTASLREGKLVTL 311

Query: 280 FGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTL 339
             +                  + G     VG +   +  T   D +++  DE   A K  
Sbjct: 312 DSV---------------GLFADGAAVRRVGDETFRVCKTLVDDMITVDTDEICNAIKLT 356

Query: 340 CLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
                ++     + A+A   K +  N    Q LV   SG  + D   +  + + 
Sbjct: 357 YNDARVVLEPAGALAVAGMRKYVHTNELSGQTLVAITSGA-NMDFDRLRFVAER 409


>UniRef50_Q2SSZ6 Threonine dehydratase n=3 Tax=Mycoplasma mycoides group
           RepID=Q2SSZ6_MYCCT
          Length = 408

 Score =  223 bits (569), Expect = 8e-57,   Method: Composition-based stats.
 Identities = 67/343 (19%), Positives = 110/343 (32%), Gaps = 42/343 (12%)

Query: 53  AGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGA 112
               T L     ++A T   +YLK E+L   G+ K      +        K   I    A
Sbjct: 20  IIHYTPLHYADKLSALTGNNIYLKLENLQKTGSFKLRGATNKINKLTNEEKKHGIIAASA 79

Query: 113 GQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNE 172
           G H    A A+  LGLK  I M       +   +      G +V+          DA  +
Sbjct: 80  GNHAQGVAFAATNLGLKSTIVMPENAPMAK---IQATEKYGGKVVL---SGRFFDDALAK 133

Query: 173 ALRDWSGSYETAHYMLGTAAGPHPYPTI-VREFQRMIGEETKAQILEREGRLPDAVIACV 231
           A+                    H +  I + + Q  I  E   QI     +  D  +  +
Sbjct: 134 AIELKEKE---------NLTLIHAFDDIEIIKGQATIAYEIDQQI-----KNIDYCLVPI 179

Query: 232 GGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTE 290
           GGG    G+         N+ +IGVE                            P+M   
Sbjct: 180 GGGGLMSGIATYLKQVNPNIKMIGVEAANVNSYQQAKALS-------------RPVMIDS 226

Query: 291 DGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALE 350
                   SI+ G+    V      + +    D V ++++E  EA   L  +   +    
Sbjct: 227 K------PSIADGIAVKKVSDLTFSILNQYVDDVVVVSEEEIAEAMLFLMENCKFVTEGS 280

Query: 351 SSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
            +   A  +       ++ + +V  +SG G+ DI  V +I+  
Sbjct: 281 GAVTAAALMFDKLNIKNQNKTIVGLVSG-GNIDIAMVGNIINK 322


>UniRef50_Q3M5I1 Cystathionine beta-synthase n=5 Tax=cellular organisms
           RepID=Q3M5I1_ANAVT
          Length = 461

 Score =  223 bits (568), Expect = 1e-56,   Method: Composition-based stats.
 Identities = 61/349 (17%), Positives = 110/349 (31%), Gaps = 50/349 (14%)

Query: 53  AGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG---KTEIIAE 109
           A   T L +   +TA   + +Y K E L  GG+ K    L     A++ G       I E
Sbjct: 10  AIGQTPLVRLNRVTANVQSPIYAKVEYLNPGGSTKDRIALSMIENAEKTGQIQPGGTIIE 69

Query: 110 TGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSG-SATLKD 168
             AG  GV  AL +A+   +C   M  K  + +   +  ++  GAEV+   +       +
Sbjct: 70  ATAGNTGVGLALIAAVKKYRCIFVMPDKMSQDK---INLLKAYGAEVVVTPTSVPPDSPE 126

Query: 169 ACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVI 228
           + N      +     A+            P          G E  A          D  +
Sbjct: 127 SYNGVAERLAKEIPGAYRP-----NQFENPNNPLAHYLTTGPEIWADSQ----GKIDVFV 177

Query: 229 ACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMM 287
           A +G G    G+         N+ ++G +P G  +                    K+  +
Sbjct: 178 AGMGTGGTISGVAKYLKEQNPNIIIVGADPEGSILS---------------GDSPKSYKV 222

Query: 288 QTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIP 347
           +                            N     + + ++D E+    + L   EG++ 
Sbjct: 223 EGIGEDFIP-----------------KTFNRQLVDEMIRVSDKESFNMARRLAREEGLLV 265

Query: 348 ALESSHALAHALKMMREN-PDKEQLLVVNLSGRGDKDIFTVHDILKARG 395
                  +A ALK        K  ++++  +GR   +       ++  G
Sbjct: 266 GGSCGTVVAAALKYAARLSQPKYIVVLLPDTGRNYINKIYSDVWMQENG 314


>UniRef50_C4Z926 Threonine dehydratase n=58 Tax=Bacteria RepID=C4Z926_EUBR3
          Length = 416

 Score =  222 bits (567), Expect = 1e-56,   Method: Composition-based stats.
 Identities = 71/352 (20%), Positives = 124/352 (35%), Gaps = 45/352 (12%)

Query: 43  AQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG 102
            + ++ +K      T L     ++  T   +YLK E++   GA+K      +        
Sbjct: 21  EEASEKVKE-VTLETKLIYSDFLSDQTGNKVYLKPENMQFTGAYKVRGAYYKISTLTDEE 79

Query: 103 KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSG 162
           + + +    AG H    A A+   G K  I M       +   V R +  GAEV+     
Sbjct: 80  RAKGLITASAGNHAQGVAYAAKCYGCKAVIVMPTTTPLIK---VNRTKSYGAEVVL---- 132

Query: 163 SATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGR 222
                D  +EA        E   Y   T   P      V   Q  I  E   ++      
Sbjct: 133 ---YGDVYDEACAKAYELAEKEGY---TFIHPFDDLA-VATGQGTIAMEIFKELP----- 180

Query: 223 LPDAVIACVGGGSNAIGMFA-DFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFG 281
           L + ++  +GGG  A G+     +    + +IGVEP G            K+G+V     
Sbjct: 181 LVEYILVPIGGGGLATGVSTLAKLLNPKIKVIGVEPAGANCMQE----SFKNGKVTTLPS 236

Query: 282 MKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCL 341
           +                +I+ G    + G            D +++ DDE + AF  +  
Sbjct: 237 V---------------NTIADGTAVKTPGSNIFPYIKKNLDDIITVEDDELIVAFLDMVE 281

Query: 342 HEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
           +  +I        +A      +    K++ +V  LSG G+ D+ T+  +++ 
Sbjct: 282 NHKMIVENSGLLTVAAL----KHLGVKDKRVVSILSG-GNMDVITMSSVVQQ 328


>UniRef50_D0N3C1 Cysteine synthase, putative n=1 Tax=Phytophthora infestans T30-4
           RepID=D0N3C1_PHYIN
          Length = 396

 Score =  222 bits (566), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 67/343 (19%), Positives = 111/343 (32%), Gaps = 33/343 (9%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG---KTEIIAETGAG 113
           T L +  +++  T   +  K E L  GG+ K     G    A+R G   +   I E  +G
Sbjct: 60  TPLIELTSLSKATGCKILAKAELLNPGGSSKDRVAKGIVEDAERRGLLKEGGTIIEGTSG 119

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPV-HSGSATLKDACNE 172
             G++ +L +   G +C I M     + +S     +   GAEV+ V  +     K   NE
Sbjct: 120 STGISLSLMARARGYRCVIVMPDDQAKEKS---QLLEQFGAEVVLVKPASIVNAKHYVNE 176

Query: 173 ALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVG 232
           A R  + + E  ++                      G E   Q         DA +   G
Sbjct: 177 AKR-LARNTEGGYFT-----DQFENTANFDSHYATTGPEIWRQ----TNGSVDAFVMAAG 226

Query: 233 GGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTED 291
            G    G  A       NV +   +P G  +                      P      
Sbjct: 227 TGGTIAGTSAYLKEQNPNVQVFLADPPGSSLYNKVRSNVCYA-----------PQQAETK 275

Query: 292 GQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALES 351
            +     +I+ G+    +             D   +TD E +E  + L   EGI     S
Sbjct: 276 VRRHRYDTIAEGV---GIDRLTENFMLAKVDDAFKVTDQEIVEMSRFLLREEGIFVGSSS 332

Query: 352 SHALAHALKMMRENPDKEQLL-VVNLSGRGDKDIFTVHDILKA 393
               A A++  R+      ++ V+  SG+     F     ++ 
Sbjct: 333 GLNCAAAVRAARKLGPGHTIVTVLCDSGQRHLTKFWNEQHIRE 375


>UniRef50_C4V2P7 Threonine ammonia-lyase n=1 Tax=Selenomonas flueggei ATCC 43531
           RepID=C4V2P7_9FIRM
          Length = 416

 Score =  222 bits (565), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 68/343 (19%), Positives = 115/343 (33%), Gaps = 46/343 (13%)

Query: 51  NYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAET 110
               R + L      +  +    YLK E+L   GA K      +  +     +   +   
Sbjct: 31  EGIVRKSPLVYSDYFSDLSGNATYLKLENLQTTGAFKLRGAYNRISMLTEEERARGVITA 90

Query: 111 GAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDAC 170
            AG H    A ++  LG+K  I M A         V   R  GA V+   +G     DA 
Sbjct: 91  SAGNHAQGVAYSAQKLGVKAVICMPATTP---ILKVEATRAFGATVVLHGNG---FDDAY 144

Query: 171 NEALRDWSGSYETAHYMLGTAAGPHPYPT-IVREFQRMIGEETKAQILEREGRLPDAVIA 229
             +L                    HP+    V   Q  I  E    + +      DA++ 
Sbjct: 145 AHSLELQKEH---------GYVYIHPFNDRNVIVGQGTIALEVIDALKD-----VDAILV 190

Query: 230 CVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQ 288
            +GGG  A G+          V +IGVEP           A L  G              
Sbjct: 191 PIGGGGLASGIALGVKTVNPQVKVIGVEPENAACM----KAALSCGHA------------ 234

Query: 289 TEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPA 348
                +  + +++ G    + G            + +++++ E + A  +L     +I  
Sbjct: 235 ---ITLPSADTVADGCAVRTAGTLTREFCRRYLDEIITVSEMEIMSALLSLIEKHKLIAE 291

Query: 349 LESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDIL 391
                +LA   K+      K++ + V +SG G+ DI T+  ++
Sbjct: 292 GAGVLSLAALQKL----HTKDKKIAVLISG-GNIDISTISALI 329


>UniRef50_B2KE33 Threonine synthase n=1 Tax=Elusimicrobium minutum Pei191
           RepID=B2KE33_ELUMP
          Length = 416

 Score =  221 bits (563), Expect = 4e-56,   Method: Composition-based stats.
 Identities = 57/341 (16%), Positives = 117/341 (34%), Gaps = 34/341 (9%)

Query: 57  TALTKCQNITAGTNT-TLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           T +   + +        L +K E     G+ K          A  +G   IIA+   G  
Sbjct: 81  TPMYDHKELADELGISKLLIKDEGRNPTGSIKDRGSAVSVARALELGLD-IIADASTGNA 139

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
             + A  +A L +K  ++        +   +F   + GA+V  V        + C +A+ 
Sbjct: 140 SDSLACLTAGLDIKTIVFTTKDAPYPKLTQLF---VYGADVFTVDGTYDDAFELCKKAVE 196

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
           ++        Y       P       RE ++    E   Q+       PD V+  VG G+
Sbjct: 197 EY------GWYSRAAGYNPF-----TREGKKTCSFEICEQL---NWEAPDKVLVAVGDGT 242

Query: 236 NAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIE 295
              GM+  F++   +G++   P    ++     A  +                  +    
Sbjct: 243 ILSGMWKGFVDFQKLGILEKMPQMIAVQAEGSDAIKRAFEN------------KGEVTAV 290

Query: 296 ESYSISAGL--DFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSH 353
           ++++I+  +  ++P                 V++TD+E L A         I      + 
Sbjct: 291 KAHTIADSILVNYPRDAQLAVQALQESDGYAVTVTDEEILAAIPEFARKANIFAEPAGAA 350

Query: 354 ALAHALKMMRENP-DKEQLLVVNLSGRGDKDIFTVHDILKA 393
             A   K+  E   ++++ + + + G G KD ++    ++ 
Sbjct: 351 VYAALKKLAEEGKIEQDETVAIVIGGNGLKDTYSYAKNIQK 391


>UniRef50_Q0W7Y3 Threonine synthase n=2 Tax=Euryarchaeota RepID=Q0W7Y3_UNCMA
          Length = 413

 Score =  219 bits (558), Expect = 1e-55,   Method: Composition-based stats.
 Identities = 72/348 (20%), Positives = 127/348 (36%), Gaps = 36/348 (10%)

Query: 57  TALTKCQNITAGTNT-TLYLKREDLLHGGAHKTNQVLGQALLA-----KRMGKTEIIAET 110
           T L + +NI        L+ K E L   G+ K      +   A             I   
Sbjct: 78  TPLVRSRNIAREPGFGELFFKLESLNPTGSFKDRGSTVEISQAYHYLCHHGECENEIVCA 137

Query: 111 GAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDAC 170
             G  G + A   A  G++C IY+     + +     +M   GAE++ V         A 
Sbjct: 138 STGNMGASVAAYCARGGIRCTIYVPNDTAKIKL---LQMMAHGAEIVRVDGDYTV---AM 191

Query: 171 NEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIAC 230
           + A R++    E   Y+ G             E ++ +G E   Q+      +PD ++  
Sbjct: 192 HTAKREY---EERGRYLAG-------DYPYRGEGEKSVGLEVIDQL----NGVPDYIVCP 237

Query: 231 VGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTE 290
           +G G+   G++         GL+   P   G++ G      +    G     +  +    
Sbjct: 238 IGNGTLVHGIWKGLKELKITGLLQRLPKIIGVQAGGCNTVARSFEEG-----RDDITPVV 292

Query: 291 DGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALE 350
              + ++ +    LD        A   S G A    ++D E   A   L   EGI   L 
Sbjct: 293 PHTLMDAVACGDPLD--GTWALRAIRESEGWATA--VSDVEGARARDLLGKKEGIFAELS 348

Query: 351 SSHALAHALKMMR-ENPDKEQLLVVNLSGRGDKDIFTVHDILKARGEI 397
            + ++A  +K  + E  +K+  +V  ++G G K+  T  D ++  GE+
Sbjct: 349 GALSMAGLIKAYQAEVIEKDARVVALVTGHGLKEPETFEDEIRTIGEL 396


>UniRef50_D1AJT1 Threonine dehydratase n=8 Tax=Bacteria RepID=D1AJT1_SEBTE
          Length = 401

 Score =  219 bits (558), Expect = 1e-55,   Method: Composition-based stats.
 Identities = 73/349 (20%), Positives = 127/349 (36%), Gaps = 45/349 (12%)

Query: 44  QFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK 103
           +  + L N   + T L      +     T+Y+K E+L   G+ K      +  +     K
Sbjct: 9   EAKERLSNVLVK-TKLIYSSTFSKEFGNTVYIKPENLQRTGSFKIRGAYNKIFMLSEEEK 67

Query: 104 TEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGS 163
            + +  + AG H    A A+  LG+K  I M       +   V      GAEV+      
Sbjct: 68  KKGLIASSAGNHAQGVAFAAQKLGVKATIVMPKHTPLIK---VEATARFGAEVVL----- 119

Query: 164 ATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRL 223
               +  +EA        E   Y+      P      V   Q  I  E   ++ +     
Sbjct: 120 --HGEVYDEAYEKAKELQEEKGYI---FVHPFDDDA-VIAGQGTIALEILKELPD----- 168

Query: 224 PDAVIAC-VGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGM 282
            D ++    GGG  +    A  +    + +IGVEP G           L  G+V      
Sbjct: 169 VDIIMVPLGGGGLISGIAAAAKLKNPEIKIIGVEPEG----AASAIKSLNEGKVT----- 219

Query: 283 KAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLH 342
                     ++ ESY+I+ G     +G            + ++++D E +E+F  L   
Sbjct: 220 ----------ELSESYTIADGAAVKRIGDTTFEYIKKYVDEIITVSDYELMESFLILVEK 269

Query: 343 EGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDIL 391
             +I       +LA      R+  +K++ +V  LSG G+ D+ T+  ++
Sbjct: 270 HKLIAENAGILSLAGL----RKIKEKDKKIVSVLSG-GNIDVLTISSMI 313


>UniRef50_Q1IPW5 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit n=3
           Tax=Bacteria RepID=Q1IPW5_ACIBL
          Length = 332

 Score =  218 bits (556), Expect = 2e-55,   Method: Composition-based stats.
 Identities = 66/353 (18%), Positives = 125/353 (35%), Gaps = 38/353 (10%)

Query: 40  EFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAK 99
           E   Q  + L+  A R   +          + TL +K E L   G+ K      +     
Sbjct: 5   ESFRQAQERLRGIAARTPLVQYFPPGHTHNDRTLRIKPESLQPIGSFKLRGAYNKIATLS 64

Query: 100 RMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPV 159
              +   +    +G H    A  +  +G+K  I M     + +       + +GAE++ V
Sbjct: 65  DEERQRGVITYSSGNHAQGVAYGARAMGVKACIVMPRNAPKVKM---DATKALGAEIVTV 121

Query: 160 HSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILER 219
              S+  +       ++            G A  P      +   Q  +G E    + E 
Sbjct: 122 GPASSERRKKAESLAQEH-----------GYAIVPPYDDEQIISGQGTVGMEIYEDLPEA 170

Query: 220 EGRLPDAVIACVGGGSNAIGMFADFI-NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGI 278
                D V+  +GGG    G+ A    + +   +IGVEP        +    L+ G++  
Sbjct: 171 -----DIVLVPIGGGGLISGVSAALKMSGSRAKIIGVEPE----LANDAQQSLRTGKIVT 221

Query: 279 YFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKT 338
               +             S +++ GL   SVG  +  +      D V++ +DE  EA + 
Sbjct: 222 LPAERV------------SSTLADGLRTQSVGDLNYEIIKQYVDDIVTVEEDEIREAMRR 269

Query: 339 LCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDIL 391
           +     ++     +   A  L   +E P    ++VV +SG G+ +   +  ++
Sbjct: 270 MMSESRLVVEPSGAVTFAAYLFHEKELPAGRNVVVV-MSG-GNIEPSLLAQVM 320


>UniRef50_Q5HMF5 Threonine dehydratase biosynthetic n=12 Tax=Bacteria
           RepID=THD1_STAEQ
          Length = 422

 Score =  218 bits (555), Expect = 4e-55,   Method: Composition-based stats.
 Identities = 68/353 (19%), Positives = 118/353 (33%), Gaps = 35/353 (9%)

Query: 42  QAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRM 101
             +    LKN   + T L     ++   N  +YLKREDL    + K         +    
Sbjct: 12  IDEAYLRLKN-IVKETPLQFDHYLSQKYNCNVYLKREDLQWVRSFKLRGAYNAISVLSNE 70

Query: 102 GKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS 161
            K + I    AG H    A  +  L LK  I+M      ++   V   +  G   + +  
Sbjct: 71  EKNKGITCASAGNHAQGVAYTAKKLNLKAVIFMPVTTPRQKINQV---KFFGDSNVEIVL 127

Query: 162 GSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREG 221
              T      +AL                   P          Q  + +E   Q  E+E 
Sbjct: 128 IGDTFDHCLAQALNYTKQHKMN-------FIDPFNNV-YTIAGQGTLAKEILNQA-EKED 178

Query: 222 RLPDAVIACVGGGSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYF 280
           +  D V A +GGG    G+   F     +  +IGVEP G         A   +  V I  
Sbjct: 179 KTFDYVFAAIGGGGLISGVSTYFKAHSPHTKIIGVEPTG---------ASSMYQSVVINH 229

Query: 281 GMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLC 340
            +       +     +  S++       VG     +      DYV + +         + 
Sbjct: 230 SIVTLENIDK---FVDGASVA------RVGDITFDIAKDKVDDYVQVDEGAVCSTILDMY 280

Query: 341 LHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
             + I+     + +++   +  ++  +K  + +V  SG G+ DI  + +I + 
Sbjct: 281 SKQAIVAEPAGALSVSALEQYKKQIENKTIVCIV--SG-GNNDINRMKEIEER 330


>UniRef50_A8M857 Pyridoxal-5'-phosphate-dependent protein beta subunit n=3
           Tax=Actinomycetales RepID=A8M857_SALAI
          Length = 447

 Score =  217 bits (552), Expect = 7e-55,   Method: Composition-based stats.
 Identities = 102/379 (26%), Positives = 147/379 (38%), Gaps = 32/379 (8%)

Query: 37  KDPEFQAQFNDLLKNY-AGRPTALTKCQNITAGTNTT--LYLKREDLLHGGAHKTNQVLG 93
           ++ E+      +L  Y + RPT L +             +++K E     G+HK    L 
Sbjct: 49  RNDEYWEIPLPVLDAYRSYRPTPLWRATRFETAVGAKVPIWVKYEGGNISGSHKLTTALA 108

Query: 94  QALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMG 153
           QA   +  G  E++  TGAGQ G A A A AL GL+C ++M    + R+      M+++G
Sbjct: 109 QAYYYRNAGARELVTGTGAGQWGTALAAACALFGLRCTVFMVGSSLSRKPYRGVLMKMLG 168

Query: 154 AEVIPVHSG-----------SATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVR 202
           AEV    SG             +L  A  EA+   +G    A  +           T   
Sbjct: 169 AEVQASPSGTTRVSRSAQGQGNSLSLAIGEAVEYAAGRDGAAFCIGSG-------ETYSI 221

Query: 203 EFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGI 262
             Q +IG E   Q+ E+ G + DAV+ CVG GSN  G+   F  E      G        
Sbjct: 222 LHQSVIGIEAGEQLQEQGGEV-DAVVGCVGAGSNFGGVALPFHAEARSQ--GTNAPLLVA 278

Query: 263 ETGEHGAPLKHGRVGIYFGMKAP-----MMQTEDGQIEESYSISAGLDFPSVGPQHAYLN 317
                   L  G                 M T         S SAGL F       + L 
Sbjct: 279 AESSSAPKLTQGIYAYDRTDSTDTSPLEAMYTIGSSYSIPDSHSAGLRFHGAAKLVSALR 338

Query: 318 STGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQL---LVV 374
            +G    ++I    ALEA +     E ++PA ES HALA A ++     D  Q    ++V
Sbjct: 339 HSGHVAAMAIDQVVALEAGQRFATTEMVVPAPESGHALAAAAQLATTGADDLQASHGVLV 398

Query: 375 NLSGRGDKDIFTVHDILKA 393
            +SG G  D+     +L  
Sbjct: 399 CVSGHGYLDLSAYQQLLDG 417


>UniRef50_Q1QC42 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit n=41
           Tax=Bacteria RepID=Q1QC42_PSYCK
          Length = 326

 Score =  216 bits (551), Expect = 9e-55,   Method: Composition-based stats.
 Identities = 62/343 (18%), Positives = 114/343 (33%), Gaps = 40/343 (11%)

Query: 44  QFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK 103
           + ++ +K Y  R T +   + +       ++ K E+    GA K                
Sbjct: 18  EAHERIKPYIHR-TPVLTSRFLNELAGCEMFFKCENFQKAGAFKVRGASNAVFGLSDEDA 76

Query: 104 TEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGS 163
              +    +G H ++ + A+   G+ C + M     E +   V   R  G  +      +
Sbjct: 77  KNGVCTHSSGNHALSLSYAAGQRGIPCNVVMPHSAPEAKKAAV---RGYGGIITECEPST 133

Query: 164 ATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRL 223
            + ++   +   +            G    P+  P  V   Q     E   Q+ E  G  
Sbjct: 134 TSREEVFAKVQAE----------TGGDFVHPYNDPR-VIAGQATCSREFLEQM-EEIGEK 181

Query: 224 PDAVIACVGGGSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGM 282
           PD V+A +GGG    G      N   +V +   EP    +   +     K G +      
Sbjct: 182 PDMVVAPIGGGGMISGTCLTLSNLAPDVKIYAAEP----LNADDAARSFKAGHIIADDA- 236

Query: 283 KAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLH 342
                           +++ GL  P +     +  S    D ++ T++E +EA K    H
Sbjct: 237 --------------PNTVADGLKVP-LKDLTWHFVSNYVTDILTATEEEIVEAMKLTWTH 281

Query: 343 EGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIF 385
             II     +  LA  LK       K+  +++     G+ D+ 
Sbjct: 282 MKIIIEPSCAVPLAVILKNKDVFAGKKVGVIITG---GNVDLD 321


>UniRef50_B0R722 Threonine ammonia-lyase n=12 Tax=cellular organisms
           RepID=B0R722_HALS3
          Length = 410

 Score =  215 bits (547), Expect = 3e-54,   Method: Composition-based stats.
 Identities = 64/346 (18%), Positives = 108/346 (31%), Gaps = 40/346 (11%)

Query: 42  QAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRM 101
                + +   A R T L      +  T   +  K E     G+ K      +       
Sbjct: 7   IRDARERVSETA-RHTPLEYSHTFSDLTGADVRPKLECFQRTGSFKIRGATNRIRTLSAD 65

Query: 102 GKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS 161
            +   +    AG H    ALA++  G+  ++ M       +   +   +  GAEV+    
Sbjct: 66  QQDAGVVTASAGNHAQGVALAASRSGVDSKVVMPESAPISK---IKATKSYGAEVVL--- 119

Query: 162 GSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREG 221
             A   DA   A    +          G           +   Q  +G E  A       
Sbjct: 120 HGADYDDAQAHAHELEAAE--------GRTYVHAFDDEYIMAGQGTLGLEIAADCPT--- 168

Query: 222 RLPDAVIACVGGGSNAIGMFADFI-NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYF 280
              D V+  +GGG    G+         +V +IGV+  G           L  G+     
Sbjct: 169 --VDTVVVPIGGGGLISGVATALKGELDDVRVIGVQAEG----ASTVARSLDKGQP---- 218

Query: 281 GMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLC 340
                        ++   +I+ G+    VG Q   +      + V+++DDE   A   L 
Sbjct: 219 -----------QAVDHVDTIADGIAVRQVGAQTFPVIQEHVDEVVTVSDDEIATALVLLL 267

Query: 341 LHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFT 386
                +     + ALA  L+   E  D E ++     G  D ++ T
Sbjct: 268 ERGKTLVEGAGATALAAVLEDKFEYADGETIVPALCGGNIDLNLLT 313


>UniRef50_B5YF95 Threonine dehydratase n=2 Tax=Dictyoglomus RepID=B5YF95_DICT6
          Length = 406

 Score =  215 bits (547), Expect = 3e-54,   Method: Composition-based stats.
 Identities = 63/350 (18%), Positives = 119/350 (34%), Gaps = 46/350 (13%)

Query: 44  QFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK 103
           + +    +     T ++  Q  +  T   ++LK E+L   GA K    +       ++ K
Sbjct: 8   ESSKERISPFIHKTPISLSQTFSDMTGKEIFLKFENLQKTGAFKIRGAINYIS---QLKK 64

Query: 104 TEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGS 163
            + +    AG H    A AS L G+   I M       +   +   +  GA+VI      
Sbjct: 65  VKGVITASAGNHAQGVAYASKLFGIPSTIVMPENTPLIK---IISTKNYGAKVIL---HG 118

Query: 164 ATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRL 223
               DA N A    +               P      +   Q  I  E    + + E   
Sbjct: 119 KVYDDAFNYAKELANEER--------LEFVPAFDDERIISGQGTIALEILEDLKDIE--- 167

Query: 224 PDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGM 282
             A+I  +GGG  A G+          + + GV+         +                
Sbjct: 168 --ALIVPIGGGGLASGILIALKEINPKIKVYGVQSNAFPSMYEK---------------- 209

Query: 283 KAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLH 342
               ++  +   +   +I+ G+     G   +++      D   + +++  EA   L   
Sbjct: 210 ----IKKVEIPKKPEQTIAEGIAVKKPGEITSHIIEKYIDDIFIVEEEKIAEAILLLLER 265

Query: 343 EGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILK 392
              +     +  LA  LK   + P+K+  +V+ LSG G+ D+  +  I++
Sbjct: 266 AKTLVEGAGASTLAAVLKYCDQIPEKK--IVLILSG-GNIDVSLLTKIIE 312


>UniRef50_A8F881 Pyridoxal-5'-phosphate-dependent protein beta subunit n=1
           Tax=Thermotoga lettingae TMO RepID=A8F881_THELT
          Length = 322

 Score =  214 bits (544), Expect = 7e-54,   Method: Composition-based stats.
 Identities = 62/352 (17%), Positives = 116/352 (32%), Gaps = 42/352 (11%)

Query: 46  NDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE 105
                +     T +   Q +   + ++++LK E+L   G+ K    +   L   R     
Sbjct: 10  AKRRISQLAHTTPVFSSQTLNILSESSVFLKAENLQKSGSFKFRGAMNFLLSLSRENLRN 69

Query: 106 IIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSAT 165
            +    +G HG A A A  +L     + +       +      ++  GA +        T
Sbjct: 70  GVVTGSSGNHGQALACAGKILNTNVTVVVPEDVSAAKL---SAIKGYGARIERC---GRT 123

Query: 166 LKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPD 225
             +  N A      +             P  +P I    Q  IG E   Q+ +      D
Sbjct: 124 STERLNRAYEISQQTGA-------IFVPPFDHPWI-MAGQGTIGLELIEQLCDF-----D 170

Query: 226 AVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKA 284
           AV+   GG     G+         N  + GVEP     ++       K G +        
Sbjct: 171 AVLVPCGGCGLISGISKAIKEILKNARVYGVEPE----QSNSTYLSFKAGHLV------- 219

Query: 285 PMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEG 344
                   +++   +I+ GL     G     +      D + +++ E   A   L     
Sbjct: 220 --------ELKNINTIADGLRTAVPGTLTFPVVQKYVDDILLVSEQEIKRAVVFLLERMK 271

Query: 345 IIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKARGE 396
           ++     +  +A    +  + P K + +V  LSG G+ D+F +   +K   +
Sbjct: 272 LLVEPSGAVTVAAL--LSGKFPLKNKKVVAILSG-GNVDLFALSKWIKEIKQ 320


>UniRef50_Q1I705 Threonine synthase n=2 Tax=Pseudomonas RepID=Q1I705_PSEE4
          Length = 414

 Score =  213 bits (543), Expect = 7e-54,   Method: Composition-based stats.
 Identities = 67/344 (19%), Positives = 121/344 (35%), Gaps = 30/344 (8%)

Query: 47  DLLKNYAGRPTALTKCQNI-TAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE 105
             +       T L +   +    +   +++K E     G+ K         LA   G + 
Sbjct: 76  RYVPRLLVGSTPLYERPGLLETDSGMRVWVKDESRQPTGSLKDRASALAVALALESGAST 135

Query: 106 IIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSAT 165
           +      G    A A  SA  GL+  I++       +     +M   GAEVI V      
Sbjct: 136 VAVA-STGNAASALAGMSAERGLRNVIFIPRTTPREKL---AQMIGYGAEVILVDG---- 187

Query: 166 LKDACNEALRDWSGSYE-TAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLP 224
              A +EA      + E    Y   T    +     + E ++ +  E   Q+     ++P
Sbjct: 188 ---AYDEAFEQCRNACESNGWYNRTTGINSY-----MTEGKKTVAFEICEQL---GWQVP 236

Query: 225 DAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKA 284
           D V   VG G     +   F +   +G I   P   G++  +     +    G+      
Sbjct: 237 DLVFVPVGNGCILGAVHKGFQDLLKLGWIERMPRLMGVQARDSNFMYRAWSSGL------ 290

Query: 285 PMMQTEDGQIEE-SYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHE 343
           P+ Q E       + SI+       +    A  +S G  +++ + D   ++A   L    
Sbjct: 291 PLEQVEKRAPTSLASSINVAFPRDRLKALRAVRDSEG--EFLCVDDTAIVQAASRLAART 348

Query: 344 GIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTV 387
           GI P   ++ + A  L+   ++P   +  V+ ++G G KD    
Sbjct: 349 GIFPEAGAASSYAGLLQYAEQHPHSRESAVLLITGSGLKDTSIY 392


>UniRef50_C6A3C7 Threonine synthase n=6 Tax=cellular organisms RepID=C6A3C7_THESM
          Length = 380

 Score =  213 bits (543), Expect = 8e-54,   Method: Composition-based stats.
 Identities = 68/336 (20%), Positives = 117/336 (34%), Gaps = 36/336 (10%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T LTK + ++      LYLK E L    + K          A  +G  + I     G   
Sbjct: 64  TPLTKAKRLSKELGVELYLKNETLNPTWSFKDRGTFIGIHRALELGFNK-IGTVSTGNMA 122

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD 176
            + A   A  GL+  I + +  VE +      + + GA+VI V      L        R 
Sbjct: 123 ASVAAYGARFGLETYILVSSTIVEEKL---KALEVYGAKVIKVRGDYGGLY------YRS 173

Query: 177 WSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSN 236
                    Y + +            E  + IG E   ++       PD V+     G  
Sbjct: 174 LEIGQRKGIYFINS------DDPFRVEGYKSIGFEIAEEV------TPDYVVIPTSSGGL 221

Query: 237 AIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEE 296
             G+   F+     GLI   P    ++        K               + +  + E 
Sbjct: 222 FRGIVKGFLELKESGLIEDLPTFVAVQAEGCSPICKAFNES----------RQKIERFEN 271

Query: 297 SYSISAGLD--FPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHA 354
            ++I+  ++  +P  G     L +  +   V+++D+E LEA + L   EGI     S+  
Sbjct: 272 PHTIAHAIENPYPPSGNAVLRLLNELKGLCVAVSDEEILEAQQDLGR-EGIFVQPASATG 330

Query: 355 LAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDI 390
           +A   K+     + +  +V  L+G G K    +  +
Sbjct: 331 IAAIKKLRGRIEE-DTKVVSILTGSGLKTHSQMKAV 365


>UniRef50_C5D2E8 Threonine dehydratase n=9 Tax=cellular organisms RepID=C5D2E8_GEOSW
          Length = 402

 Score =  213 bits (543), Expect = 8e-54,   Method: Composition-based stats.
 Identities = 67/351 (19%), Positives = 114/351 (32%), Gaps = 43/351 (12%)

Query: 44  QFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK 103
           +  + +K      T L   Q  T  +   +Y+K E+L   G+ K      + +      +
Sbjct: 9   EAREKMK-GIVHQTPLEHSQTFTNLSGNEVYMKLENLQKTGSFKVRGSFNKIMSLSEEER 67

Query: 104 TEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGS 163
              +    AG H    A +S ++G+ C I M       +   V   +  GAEVI      
Sbjct: 68  KRGVIAASAGNHAQGVAYSSGMIGIPCTIVMPKGAPLSK---VEATKGYGAEVILHGDVF 124

Query: 164 ATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRL 223
               +   E  R              T   P      V   Q  IG E   Q+ +     
Sbjct: 125 DESLEYAFELQRQRGA----------TFVHPFDDLA-VMAGQGTIGLEIIEQLPD----- 168

Query: 224 PDAVIACVGGGSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGM 282
            D V+  VGGG    G+         ++ + GVE                        GM
Sbjct: 169 VDVVLCPVGGGGLLAGLAFTLKQLKPSIQVYGVESSACP-------------------GM 209

Query: 283 KAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLH 342
            A +   +   I  S +I+ G+     G              V + + E       L   
Sbjct: 210 TAALRHKKPITITSSDTIADGIAVKKPGNITYQYIEKYVDGVVCVEEAEISRTMLYLLER 269

Query: 343 EGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
             ++    ++  LA    + ++ P   + +V  LSG G+ D+  +  I++ 
Sbjct: 270 NKLLVEGSAACPLAAL--LYQKFPFTRKKVVTILSG-GNVDVTLISRIIER 317


>UniRef50_Q97CB2 Threonine deaminase n=4 Tax=Thermoplasmatales RepID=Q97CB2_THEVO
          Length = 406

 Score =  213 bits (542), Expect = 1e-53,   Method: Composition-based stats.
 Identities = 66/364 (18%), Positives = 120/364 (32%), Gaps = 45/364 (12%)

Query: 36  QKDPEFQA--QFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLG 93
            + P F    +    L+    R T L +   I       +Y K E+    G+ K+   + 
Sbjct: 4   LEIPSFDEIIEAQRYLEGKVNR-TPLIRSTTIGKEYGADIYFKLENFQKTGSFKSRGAIF 62

Query: 94  QALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMG 153
           +        K   +    AG H    A A+ + G+  +I M    +      V  +   G
Sbjct: 63  RFSKLSEDEKRHGVITASAGNHAQGVAYAAMINGIDAKIVMPEYTI---PQKVNAVISYG 119

Query: 154 AEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETK 213
           A VI   S         +E  +     +  A                V   Q  IG E  
Sbjct: 120 AHVILKGSDYDEAHRYADEIAKQEGRIFIEAF-----------NDRWVISGQGTIGLEIM 168

Query: 214 AQILEREGRLPDAVIACVGGGSNAIGMFADFINETN-VGLIGVEPGGHGIETGEHGAPLK 272
             + +      D ++  VGGG    G+     + +N V +IG+E       +    A L+
Sbjct: 169 EDLPD-----VDIILVPVGGGGLISGIALAAKHASNKVKVIGIESE----LSDSMKASLR 219

Query: 273 HGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEA 332
            G++  +                   SI  G+     G     +      D V++T++  
Sbjct: 220 EGKIVAH---------------TSGVSICDGISVKYPGVLTFDIARKYVDDIVTVTEEYV 264

Query: 333 LEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILK 392
            +A   L     I+     +  LA  ++   +   K + + + +SG G+ +   +  I+ 
Sbjct: 265 SKAIYKLFERNKIVAEPSGAVGLAAIME--GKVDVKGKKVAIVVSG-GNINPLLMSKIIY 321

Query: 393 ARGE 396
              E
Sbjct: 322 KELE 325


>UniRef50_A3DKP7 L-threonine synthase n=2 Tax=Desulfurococcaceae RepID=A3DKP7_STAMF
          Length = 423

 Score =  211 bits (538), Expect = 3e-53,   Method: Composition-based stats.
 Identities = 72/372 (19%), Positives = 129/372 (34%), Gaps = 30/372 (8%)

Query: 25  LRQLEEAFVSAQKDPEFQAQFND-LLKNYAGRPTALTKCQNITAGTNTT-LYLKREDLLH 82
              L +      +  EF    ++  + +     T L K   +        LYLK E    
Sbjct: 47  PEDLAKREFYMWRYKEFLPVPDEKYIVSIGEGGTPLIKANRLAEKLGLKNLYLKDETRNP 106

Query: 83  GGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQ 142
            G+ K   +     +AK  G    +  +       A A   A  G++   ++       +
Sbjct: 107 TGSFKDRCMSVSVSMAKYFGFKRAVVASSGN-AAAALAAYGARAGIEVYAFVPDFAGYGK 165

Query: 143 SPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVR 202
              + ++   GA+V  V       +D   + +R  +  Y    Y   +     P+     
Sbjct: 166 ---IAQLLFYGAKVFRVR--WVEAEDPTVKMMRLLAEKY--GFYPSPSF---GPFNPYQI 215

Query: 203 EFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGI 262
           E  + I  E   Q+      +PD V    G  S   G++  F +  NVG I   P    +
Sbjct: 216 EGPKTIAMEIVEQL---GWDVPDQVFVPTGAASLLTGVYNGFRDWNNVGWINKYPRMVAV 272

Query: 263 ETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLD----FPSVGPQHAYLNS 318
           +   +   ++            P  +          +I+ GL+    +       A  N+
Sbjct: 273 QPEGNHPFVRAWMEKADPNKIKPWEK-------PPETIATGLEDTFPWDGDAGLRALYNT 325

Query: 319 TGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDK-EQLLVVNLS 377
            G    V ++D+E LEA K L   EG+      +  LA  +K + +     ++ +VV ++
Sbjct: 326 NGYG--VVVSDEEILEAMKLLASLEGLFAEPSGAAGLAGLIKALEDGKVDRDETIVVLVT 383

Query: 378 GRGDKDIFTVHD 389
           G G KD   V  
Sbjct: 384 GHGLKDPDIVKK 395


>UniRef50_D1C5Q2 Cystathionine beta-synthase n=30 Tax=Bacteria RepID=D1C5Q2_SPHTD
          Length = 479

 Score =  211 bits (538), Expect = 3e-53,   Method: Composition-based stats.
 Identities = 67/350 (19%), Positives = 116/350 (33%), Gaps = 50/350 (14%)

Query: 53  AGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG---KTEIIAE 109
               T L +   +T G  T +  K E +  GG+ K          A+R G       I E
Sbjct: 22  LIGETPLVRLNRVTQGITTPVVAKVEFVNPGGSVKDRIGFRMIEEAERRGWLKPGGTIVE 81

Query: 110 TGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSG-SATLKD 168
             +G  GV  A+A+A+ G +C   M  K  + +   V  +R  GAEV+   +       +
Sbjct: 82  PTSGNTGVGLAMAAAVRGYRCVFVMPDKVSQEK---VALLRAYGAEVVTTPTAVPRESPE 138

Query: 169 ACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVI 228
           +        +     A          +  P   R      G E   Q            +
Sbjct: 139 SYYSVADRLTREIPGAFQP-----NQYFNPINPRAHYETTGPEIWRQ----TEGKVTHFV 189

Query: 229 ACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMM 287
           A VG G    G+         N+ +IG +P G      ++              ++   +
Sbjct: 190 AGVGTGGTISGVGRYLKEQNPNIKVIGADPEGSIYTDPDN--------------IRPYKV 235

Query: 288 QTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIP 347
           +             A +D                 +++ ++D ++    + +   EG++ 
Sbjct: 236 EGIGEDFWPGTFDRAVVD-----------------EFIQVSDRDSFLTARRVTREEGLLV 278

Query: 348 ALESSHALAHALKMMRENPDKEQLLVVNL--SGRGDKDIFTVHDILKARG 395
                 A+  AL++     D E L+VV L  SGRG        D ++  G
Sbjct: 279 GGSGGTAVWAALQVAARLDDPESLVVVLLPDSGRGYLSKVYNDDWMRENG 328


>UniRef50_B6JWQ1 Threonine dehydratase n=1 Tax=Schizosaccharomyces japonicus yFS275
           RepID=B6JWQ1_SCHJY
          Length = 605

 Score =  211 bits (538), Expect = 3e-53,   Method: Composition-based stats.
 Identities = 73/368 (19%), Positives = 120/368 (32%), Gaps = 40/368 (10%)

Query: 29  EEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKT 88
            +    A   P++             + T LTK   I+ G    +YLKREDL    + K 
Sbjct: 91  PKEMREADGTPDYLRLTLTSRIYDVMKETPLTKGVVISEGVGCPVYLKREDLTPVFSFKL 150

Query: 89  NQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFR 148
                +            +    AG H    A A+  +G+K  I M     E +  NV  
Sbjct: 151 RGAYNKMASLTPEETKNGVIACSAGNHAQGVAYAARHMGIKATIIMPRNTPEVKWKNV-- 208

Query: 149 MRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMI 208
            + +GAE + V        +A  E  R                  P+  P  V   Q  I
Sbjct: 209 -QRLGAEAVLV---GDNFDEAKAECTRLAKEHN-------LPIIHPYDDP-YVIAGQGTI 256

Query: 209 GEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEH 267
            +E   Q+     +  DA+   VGG     G+ A       +V +IGVE           
Sbjct: 257 AKEVLQQVD---LKKLDAIYIAVGGAGLLAGVSAYVKRLAPHVKVIGVETF--------- 304

Query: 268 GAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSI 327
                          K  +   +   ++E+   + G      G +   + S    D V +
Sbjct: 305 ----------DADAFKRSVENGKRVTLKEAGLFADGTAVKVNGVESFRVASENVDDVVLV 354

Query: 328 TDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPD--KEQLLVVNLSGRGDKDIF 385
             DE   A K + +    I     + ++A   + +  +P    +   V  LSG  + D  
Sbjct: 355 NKDEICAAIKDVFMDTRSIIEPSGALSVAGMKRYLSMHPPSRPDAAQVCVLSGA-NMDFD 413

Query: 386 TVHDILKA 393
            +  + + 
Sbjct: 414 RLRFVAER 421


>UniRef50_D2S0A7 Threonine synthase n=6 Tax=Halobacteriaceae RepID=D2S0A7_9EURY
          Length = 419

 Score =  211 bits (537), Expect = 4e-53,   Method: Composition-based stats.
 Identities = 66/342 (19%), Positives = 112/342 (32%), Gaps = 28/342 (8%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T L    N++        +K +     G  K          AK  G+  II     G   
Sbjct: 84  TDLFDAPNLSEALGVETLVKDDGRNPTGCFKDRASSIAVTKAKHAGRD-IITCASTGNAA 142

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD 176
            + +  +A  GL CRI++       +        + GA+V+ V+       D   E   +
Sbjct: 143 ASLSGYAARGGLDCRIFVPGAAPAGKLAQPL---VYGADVLAVNGSYDEAYDLSVEVTDE 199

Query: 177 WSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSN 236
           +        Y    A  P        E +R +G E   Q     G +PD V+  +G G  
Sbjct: 200 Y------GWYNRNAAINPFQ-----VEGKRTVGHELAEQSK-VRGDVPDWVVFSMGDGCT 247

Query: 237 AIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEE 296
             G +  F    ++  +   P   G++     A     +        A  +         
Sbjct: 248 IAGAWKGFKEFYDLDYVDDYPKMLGVQAEGASAIHDAFQGHEDIDDIAETIADSIAVGRP 307

Query: 297 SYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALA 356
             +I A                    D V ++D++ LEA K L   EGI      +  +A
Sbjct: 308 RNTIKA-----------CRAPEQSGGDTVLVSDEDILEAEKLLGSTEGIYAEPAGATPVA 356

Query: 357 HALK-MMRENPDKEQLLVVNLSGRGDKDIFTVHDILKARGEI 397
              + + R   ++++ +VV  +G G KD  +          I
Sbjct: 357 GVREALKRGIIERDETVVVVSTGFGLKDTESAKKATGDVNRI 398


>UniRef50_C6A508 Probable threonine synthase n=1 Tax=Thermococcus sibiricus MM 739
           RepID=C6A508_THESM
          Length = 392

 Score =  211 bits (537), Expect = 4e-53,   Method: Composition-based stats.
 Identities = 74/376 (19%), Positives = 133/376 (35%), Gaps = 46/376 (12%)

Query: 34  SAQKDPEFQ-AQFNDLLKNYAGRP--------------TALTKCQNITAGTNT-TLYLKR 77
              +D +    +   L K +   P              T L + +N+        LY+K 
Sbjct: 45  ELVEDNDAWFREAPRLWKYWMFYPISNLRKIVSLNEGGTRLYRMKNLEKKLGFGKLYIKN 104

Query: 78  EDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAK 137
           E     GA K      +   A      +++     G    + +   +  GL+  I +   
Sbjct: 105 EGENPTGAFKDRGSSVEITKALEFHARKVVVA-STGNMAASISAYGSKAGLEVTIVVPEG 163

Query: 138 DVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPY 197
                   + +  + GA++        T  +A  E+ R    + E  +Y+ G        
Sbjct: 164 TP---IGKLVQAVVYGAKI---KIHGTTYDEALAESER---MAKEEDYYLTG-------N 207

Query: 198 PTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEP 257
                E Q+  G E   Q+       PD ++  +G G++   ++        VGLI   P
Sbjct: 208 YHYRVEGQKSTGFEIFDQLR---FDSPDWIVVPIGAGTHLRAIWKAAKEFYKVGLIERLP 264

Query: 258 GGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLN 317
              G++   + A +K  + G        M      + + + + +  +  P  G       
Sbjct: 265 KIAGVQVEGYDAIVKAWKEG--------MPIKPRKEKKPTVASAIAVKAPVDGENVLRAI 316

Query: 318 STGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMREN-PDKEQLLVVNL 376
              +     +T++EA+ A   L   EG+     SS ALA A +M  E   DK++ +VV  
Sbjct: 317 EESKGHLGVVTNEEAMNAGLLLGK-EGLFVEPSSSTALALARQMREEGIIDKDERIVVIA 375

Query: 377 SGRGDKDIFTVHDILK 392
           +G G KD  T    +K
Sbjct: 376 TGHGLKDTKTWESFIK 391


>UniRef50_O59701 Cysteine synthase 1 n=133 Tax=cellular organisms RepID=CYSK1_SCHPO
          Length = 351

 Score =  209 bits (533), Expect = 1e-52,   Method: Composition-based stats.
 Identities = 63/349 (18%), Positives = 109/349 (31%), Gaps = 35/349 (10%)

Query: 53  AGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK---TEIIAE 109
           A   T L +   ++  T   +  K E    GG+ K          A++ GK      I E
Sbjct: 20  AIGRTPLIRLNTLSNETGCNILAKAEFQNPGGSVKDRAAYYVVRDAEKKGKLSRGGTIVE 79

Query: 110 TGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDA 169
             AG  G+  A  +   G KC IYM     + +   +  ++ +GAEV PV     +    
Sbjct: 80  GTAGNTGIGLAHIARARGYKCVIYMPNTQSQAK---IDTLKFLGAEVHPVPVAPFSNPLN 136

Query: 170 CNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIA 229
            N   R  + S   A     +          +       G E   Q         D    
Sbjct: 137 YNHQARRHAESTPNA-----SWTDQFDNVANLLSHYETTGPEIWDQTKGT----VDGFTC 187

Query: 230 CVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQT 289
             G G    G+      +++  +        G                +Y  +K      
Sbjct: 188 STGTGGTFAGVTKYLKEKSDGRVASFVADPPG--------------SVLYSHIKTKGKHP 233

Query: 290 EDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPAL 349
           ++     +  I  G    +V P           D + I D++++  F  L   EG+    
Sbjct: 234 DNKGSSFTEGIGQGRITGNVQP-----VYDLIDDAMKIPDEKSINMFFRLLDQEGLFLGG 288

Query: 350 ESSHALAHALKMMRE-NPDKEQLLVVNLSGRGDKDIFTVHDILKARGEI 397
            S   +  A++M +   P K  + ++  SG            L+++   
Sbjct: 289 SSCLNVVAAVEMAKILGPGKTVVTILCDSGHKYATRLFSRSFLESKKLF 337


>UniRef50_C0WC35 Threonine dehydratase n=1 Tax=Acidaminococcus sp. D21
           RepID=C0WC35_9FIRM
          Length = 404

 Score =  209 bits (531), Expect = 2e-52,   Method: Composition-based stats.
 Identities = 65/353 (18%), Positives = 115/353 (32%), Gaps = 44/353 (12%)

Query: 42  QAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRM 101
             +    LK      T L     IT   +   YLK E+L   G+ K        +     
Sbjct: 11  IEEARARLK-GLVHETPLDMSHTITTLADRETYLKLENLQRTGSFKIRGASNCIMTLSPE 69

Query: 102 GKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS 161
            K   I    AG H    AL   +  ++  + M       +   V   +  GA V+    
Sbjct: 70  QKERGIIAASAGNHAQGVALGGTMNAIRSTVVMPEAAPLAK---VQATKGYGANVVL--- 123

Query: 162 GSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREG 221
              T  ++  +A+         A++       P+  P +V   Q  +G E   Q  + E 
Sbjct: 124 HGKTFDESLAKAME--IQKETGAYF-----VHPYDDP-MVIAGQGTVGLEILEQCPDIEN 175

Query: 222 RLPDAVIACVGGGSNAIGMFADFI-NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYF 280
                ++   GGG    G+         +V + GV          E    +  G+     
Sbjct: 176 -----IVVPAGGGGLLSGIATAVKNKAPHVKVYGV--------QSEKAPAIYLGKK---- 218

Query: 281 GMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLC 340
                  Q +        +I+ G      G     L      D + + +++   A   + 
Sbjct: 219 -------QNKWVSHPSGKTIADGCAVGMPGKLTFSLIQKYVDDMLLVKEEDIAAAMLLVL 271

Query: 341 LHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
               ++     +  +A AL+ +   P K  L++   SG G+ D+ TV  I++ 
Sbjct: 272 ERGKLVMEGAGAMPVAAALQHLIPTPGKTALVI---SG-GNIDVNTVSRIIET 320


>UniRef50_D1Y7Y8 Threonine synthase n=1 Tax=Pyramidobacter piscolens W5455
           RepID=D1Y7Y8_9BACT
          Length = 409

 Score =  209 bits (531), Expect = 2e-52,   Method: Composition-based stats.
 Identities = 72/372 (19%), Positives = 123/372 (33%), Gaps = 42/372 (11%)

Query: 34  SAQKDPEFQAQFNDLL---KNYAGRPT------ALTKCQNITAGTNT-TLYLKREDLLHG 83
           S   DP F     + L   +  + RPT       L     I +  +   L +K +     
Sbjct: 50  SLAADPRFSLWRYEALLPMRKNSRRPTLQVGWTPLYDMPQIASEYDVGQLLIKDDGRNPT 109

Query: 84  GAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQS 143
            + K         LA    +  ++A    G    + A  +A +GLK  I++       + 
Sbjct: 110 ASLKDRASAVAVTLAAERNRD-VLACASTGNAASSLAGFAANMGLKSVIFVPETAPVAK- 167

Query: 144 PNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVRE 203
             V ++ + GA V  V    A       EA+  +        Y    A  P      + E
Sbjct: 168 --VTQLLVFGARVFLVKGDYAAAVRLAIEAIEHY------GWYDRNCAINPF-----LVE 214

Query: 204 FQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIE 263
            ++    E   Q       +PD V   VG G      +  F +   +G+I   P   G++
Sbjct: 215 GKKTCAMEIAEQCD---WDVPDKVFVSVGDGCIVSSTYKGFYDLYKIGVIDRIPQIIGVQ 271

Query: 264 TGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYL--NSTGR 321
                   +  + G            +      S++I+  +D  +       L       
Sbjct: 272 AEGACPIHRAIQEG-----------ADKIVFGPSHTIADSIDVGAPHNWAKALHAIRASH 320

Query: 322 ADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDK-EQLLVVNLSGRG 380
            D  +++D E L A   L    G+      + A A  +K  RE   K    + V +SG G
Sbjct: 321 GDTTAVSDAEILSAVAELPRKSGVFAEPAGATAYAGFVKFAREGRLKASDRVAVIISGNG 380

Query: 381 DKDIFTVHDILK 392
            KD+ +    + 
Sbjct: 381 LKDVASAQKAVP 392


>UniRef50_C1PE10 Threonine dehydratase n=2 Tax=Bacillaceae RepID=C1PE10_BACCO
          Length = 350

 Score =  208 bits (530), Expect = 3e-52,   Method: Composition-based stats.
 Identities = 76/363 (20%), Positives = 119/363 (32%), Gaps = 44/363 (12%)

Query: 36  QKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQA 95
            +  +  A F +LL       T L +         T LY K E+L   G+ K    L + 
Sbjct: 22  LQTKDIVAAFENLL--PVVHRTPLNESATFNEMAGTRLYFKMENLQRTGSFKIRGALNKI 79

Query: 96  LLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAE 155
                  +   +    AG H    A ++   GLK +IYM  K    +   V   +  GAE
Sbjct: 80  TNLTGDARKNGVIAASAGNHAQGVAFSATKQGLKAKIYMPEKTPLAK---VLATKAYGAE 136

Query: 156 VIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTI-VREFQRMIGEETKA 214
           V+          ++  EA        +     +  A   HP+    V   Q  I  E   
Sbjct: 137 VVLT-------GESFQEAYEAAVLDQQ-----ITGATFIHPFDDYEVMAGQGTIALEMIQ 184

Query: 215 QILEREGRLPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKH 273
           Q  +      D V+  VGGG    GM     N +  + +IGV+  G              
Sbjct: 185 QCADL-----DTVVIPVGGGGLIAGMACLLKNYDPKIRVIGVQSEGAPAAYNRFKGMG-- 237

Query: 274 GRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEAL 333
                            + ++E    I+ G+     G     L S    D V+++D++  
Sbjct: 238 -----------------NSRLEHVSGIADGILVKETGQLTFPLISKYVDDVVTVSDEDIA 280

Query: 334 EAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
            A   +   E +      + A A  L        K   +VV+  G  D D  +    L  
Sbjct: 281 TAIIYMLEREKMFVEGAGAAAFAAVLSGKAGVSGKHVGIVVS-GGNADLDKISHFKRLAT 339

Query: 394 RGE 396
            G+
Sbjct: 340 AGK 342


>UniRef50_A8MDC1 Threonine dehydratase n=9 Tax=cellular organisms RepID=A8MDC1_CALMQ
          Length = 418

 Score =  208 bits (530), Expect = 3e-52,   Method: Composition-based stats.
 Identities = 70/365 (19%), Positives = 114/365 (31%), Gaps = 44/365 (12%)

Query: 28  LEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHK 87
           +       +   E      D         T L +   +++ TN  +YLK E L   G+ K
Sbjct: 8   ITRVNEVYELSREALTLIKDAQAKGIIHRTPLYRSDTLSSLTNADVYLKLEALQKTGSFK 67

Query: 88  TNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVF 147
                             ++    AG H    A  + + GLK  I M       +  N  
Sbjct: 68  VRGAYNAVTHYINDDVKHVVTA-SAGNHAQGVAYVAKIYGLKSTIVMPKYTPWIKISNT- 125

Query: 148 RMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRM 207
             R  GAEVI         +    E  ++       A+               V   Q  
Sbjct: 126 --RKYGAEVILEGQSYYEAEKYAIELTKELKAKMIHAY-----------DDPFVIAGQGT 172

Query: 208 IGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGE 266
           IG E    +     +  D VI  VGGG    G+ +       N  +IGV+          
Sbjct: 173 IGWEIIEDL-----KNIDYVIVPVGGGGLISGIASVIKTISPNTRVIGVQSEITPSAYLS 227

Query: 267 HGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVS 326
                              + Q +   +E + +I+ G+    +G     +      D V 
Sbjct: 228 -------------------LKQGKIITVENTDTIADGIAVKKIGDLTFDIMRNTLDDVVL 268

Query: 327 ITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFT 386
           ++D E + A   L     +I       A A A  +  +   K  ++ V  SG G+ D+  
Sbjct: 269 VSDQEIVNAILILAESAKVIAEGA--GAAAVAALLSGKINVKGNVVAVV-SG-GNIDVTM 324

Query: 387 VHDIL 391
           +  +L
Sbjct: 325 LAKVL 329


>UniRef50_A5CWZ8 Threonine dehydratase n=1 Tax=Candidatus Vesicomyosocius okutanii
           HA RepID=A5CWZ8_VESOH
          Length = 325

 Score =  208 bits (529), Expect = 3e-52,   Method: Composition-based stats.
 Identities = 63/350 (18%), Positives = 115/350 (32%), Gaps = 42/350 (12%)

Query: 41  FQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKR 100
             ++    + N   R T L     I+   +  +YLKREDL    + K      +      
Sbjct: 4   IVSRIKRDVVNEVVRKTQLEFASQISMHLDNKIYLKREDLTPVHSFKLRGAYHKIRTLNI 63

Query: 101 MGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVH 160
              ++ +    AG H    A ++  LG+   I M     + +  +V   + +GAEVI   
Sbjct: 64  RQLSKGVITCSAGNHAQGVAFSAKKLGIYAVIVMPKITPKIKVDSV---KSLGAEVILFG 120

Query: 161 SGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTI-VREFQRMIGEETKAQILER 219
           +      D             +   ++       H +  + V   Q  I  E   Q+ + 
Sbjct: 121 NSYDVAYD-----FSQNIAKKKGYTFI-------HAFDDLDVIAGQGTIAYELLEQLDDI 168

Query: 220 EGRLPDAVIACVGGGSNAIGMFADFI-NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGI 278
                D +   VGGG    G+ +        + +IGVEP G    T              
Sbjct: 169 -----DYIFVPVGGGGLITGIASVIKTQRPKIKIIGVEPVGSAAFTRS------------ 211

Query: 279 YFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKT 338
                  +       ++E    + G+    VG ++  +        V +++DE   A K 
Sbjct: 212 -------ITSNTHAVLDEVDVFAEGVAVKKVGFENLRIAKKLVNGTVLVSNDEMCAAIKD 264

Query: 339 LCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSG-RGDKDIFTV 387
           +      I     + ALA   + + +       ++  +SG   + D    
Sbjct: 265 IYNQNRYIVEPSGALALAGIKRYIFDKQLHNNNIISIVSGANMNFDRLRY 314


>UniRef50_A5N599 IlvE1 n=23 Tax=Bacteria RepID=A5N599_CLOK5
          Length = 412

 Score =  207 bits (528), Expect = 4e-52,   Method: Composition-based stats.
 Identities = 70/365 (19%), Positives = 122/365 (33%), Gaps = 45/365 (12%)

Query: 28  LEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHK 87
           L      A    E   +    +K+     T L      +  +   +Y+K E+L   GA K
Sbjct: 5   LTLETEEAHLTLEDVLEARKRIKDICI-DTELIYSSEYSLESGNEVYIKPENLQITGAFK 63

Query: 88  TNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVF 147
               L +        K + +  + AG H    A A+  LG+K  I M       +   V 
Sbjct: 64  LRGALNKISKLSEDNKKKGLIASSAGNHAQGVAYAANKLGIKATIVMPETTPLIK---VQ 120

Query: 148 RMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRM 207
             +  GAEV+          +A  EA R              T   P      V   Q  
Sbjct: 121 ATKNYGAEVVL---KGKVYDEAYEEAKRLEKEKG-------YTFIHPFDDLD-VMAGQGT 169

Query: 208 IGEETKAQILEREGRLPDAVIAC-VGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGE 266
           I  E   ++ +      DA++    GGG  +    A      N+ +IGV+  G       
Sbjct: 170 IALEIIEKLKD-----VDAIVVPIGGGGLISGISVAAKSINPNIKIIGVQADG----ANP 220

Query: 267 HGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVS 326
                  G++                   +  +I+ G    + G     +      + V+
Sbjct: 221 MKYSFDTGKLTSAE---------------DIDTIADGAAVKNPGKLTFQVVKKYVDEIVT 265

Query: 327 ITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFT 386
           ++D + +E    L     ++     + +LA   K+      K + +V  +SG G+ D+ T
Sbjct: 266 VSDQQLMEDVYILLEKHKLVAEATGAMSLAALSKL----KFKNKKVVCLISG-GNIDVVT 320

Query: 387 VHDIL 391
           +  +L
Sbjct: 321 MSALL 325


>UniRef50_C5CHS7 Threonine synthase n=2 Tax=Thermotogaceae RepID=C5CHS7_KOSOT
          Length = 419

 Score =  207 bits (526), Expect = 8e-52,   Method: Composition-based stats.
 Identities = 62/358 (17%), Positives = 121/358 (33%), Gaps = 28/358 (7%)

Query: 42  QAQFNDLLKNYAGRPTALTKCQNITAGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKR 100
              F++L+       T L +   I        + +K +      + K        + AK 
Sbjct: 72  PENFDELIPPLLVGNTPLYRADKIAGKYGVAEVLVKDDGRNPTASFKDRASALAVVKAKE 131

Query: 101 MGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVH 160
            G   +      G    + A  +A  GLK  I++ A     +     ++++ GA+V+ + 
Sbjct: 132 KGYNTVFCA-STGNAASSLAGLTAAAGLKSVIFVPASAPAAKL---TQLQVYGAKVLAID 187

Query: 161 SGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILERE 220
                  D             E   Y   +A  P+     + E ++    E   Q     
Sbjct: 188 GSYDEAFDI------SMIVGMEKGWYCRNSAINPY-----LLEGKKTGALELAVQ---TG 233

Query: 221 GRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYF 280
             LPD V   VG G+     +  F++   +G+I   P   G++     A +     G   
Sbjct: 234 MDLPDFVFVSVGDGTVLSSFYKAFMDLKELGIIERIPTIVGVQAENASAIIDTYERG--- 290

Query: 281 GMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLC 340
               P    +      + SI+ G     +        + G   +V ++D E L++   L 
Sbjct: 291 ---EPFTPADLDAHSVADSIAVGKPRDVIKACKYTKKNGGL--FVKVSDKEILDSIIELA 345

Query: 341 LHEGIIPALESSHALAHALKMMRENP-DKEQLLVVNLSGRGDKDIFTVHDILKARGEI 397
              G+      + A A   +M       +   + + ++G G KD+     +L+   ++
Sbjct: 346 RGTGVFAEPAGATAFAGFKRMKSLGQISESARVALIVTGNGLKDLKAPARVLEELKKL 403


>UniRef50_A9BIT3 Threonine synthase n=4 Tax=Bacteria RepID=A9BIT3_PETMO
          Length = 421

 Score =  207 bits (526), Expect = 8e-52,   Method: Composition-based stats.
 Identities = 72/368 (19%), Positives = 125/368 (33%), Gaps = 39/368 (10%)

Query: 34  SAQKDPEFQA-------QFNDLLKNYAGRPTALTKCQNITAGTNTT-LYLKREDLLHGGA 85
            A  DP           + N          T L K   +        LY+K + L   G+
Sbjct: 58  KANPDPSIWRYSPLLPIEPNTPKPPLKIGGTPLYKSDVMAKLLGIETLYIKDDGLNPTGS 117

Query: 86  HKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLG--LKCRIYMGAKDVERQS 143
            K        + A+  G   I+A    G    + A   A +G  +K  I++ ++      
Sbjct: 118 LKDRASAIAVVKAQEAGMN-IVACASTGNAASSLAGNIASMGNEMKAVIFVPSRAP---I 173

Query: 144 PNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVRE 203
             V ++ + GA V+ V            +A+  W        Y    A  P+     + E
Sbjct: 174 GKVTQLLVFGALVLSVKGSYEETFYLSQQAIDKW------GWYNRNAAINPY-----LVE 222

Query: 204 FQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIE 263
            ++    E   Q+      + D ++  VG G    G +    +   +G I   P   G++
Sbjct: 223 GKKTSSIEIAEQL---NWEMVDWLVYSVGDGCTIAGAWKGMYDLKQIGFIDKLPRLLGVQ 279

Query: 264 TGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRAD 323
           +           +   F     ++   +  I +  SI+ G     +    A  +S G  D
Sbjct: 280 SEGCAP------ITQAFKSDTDLVPVPENTIAD--SIAVGKPRNYIKAIKAVKDSNG--D 329

Query: 324 YVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDK-EQLLVVNLSGRGDK 382
            +++TDDE L   K L  + GI         +A   K +     K  + + V ++G G K
Sbjct: 330 MINVTDDEILNMIKILGKNTGIFGEPAGVAGVAGIKKAVENGIIKPSESVAVVVTGNGLK 389

Query: 383 DIFTVHDI 390
           DI      
Sbjct: 390 DIKNAEKA 397


>UniRef50_D1NGU1 DNA (Cytosine-5-)-methyltransferase (Fragment) n=3 Tax=Haemophilus
           influenzae HK1212 RepID=D1NGU1_HAEIN
          Length = 256

 Score =  206 bits (525), Expect = 9e-52,   Method: Composition-based stats.
 Identities = 145/228 (63%), Positives = 161/228 (70%), Gaps = 30/228 (13%)

Query: 38  DPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALL 97
           DP FQA+F DLLKNYAGRPTALT C N+T GT   +YLKREDLLHGGAHKTNQVLGQ LL
Sbjct: 1   DPTFQAEFADLLKNYAGRPTALTLCHNLTKGTKAKIYLKREDLLHGGAHKTNQVLGQILL 60

Query: 98  AKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVI 157
           AKRMGKT IIAETGAGQHGVA+ALA A+L + CRIYMGAKDV+RQSPNVFRMRLMGAEVI
Sbjct: 61  AKRMGKTRIIAETGAGQHGVATALACAMLDMPCRIYMGAKDVDRQSPNVFRMRLMGAEVI 120

Query: 158 PVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREF------------- 204
           PV  GS +LKDAC EA+RDWS +YET HY+LGTAAGPHP+PTIVREF             
Sbjct: 121 PVQKGSCSLKDACCEAMRDWSANYETTHYLLGTAAGPHPFPTIVREFNNNGKMIKNWFEW 180

Query: 205 --------------QRMIGEETKAQILEREGRLPDAVIACV-GGGSNA 237
                         Q+ I      +++E      D VI  V G  S  
Sbjct: 181 EKDNRKEIPKLHPTQKPIA--VLKRLIEIFTDEGDVVIDPVAGSASTL 226


>UniRef50_A0LFH6 Cysteine synthases n=15 Tax=cellular organisms RepID=A0LFH6_SYNFM
          Length = 773

 Score =  206 bits (524), Expect = 1e-51,   Method: Composition-based stats.
 Identities = 63/340 (18%), Positives = 108/340 (31%), Gaps = 55/340 (16%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK---TEIIAETGAG 113
           T L +   +      TLY K E    GG+ K    L     A+R G     +II E  +G
Sbjct: 15  TPLIRINRLNPNPAVTLYAKLEAKNPGGSIKDRTALFMIESAERDGLLTHEKIIIEATSG 74

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
             G+  A+ +A+ G +  + M              ++ +GAE++       T  D   E 
Sbjct: 75  NTGIGLAIVAAVKGYRLMLAMPETA---SLERQKILKALGAEILLTPGNLGT--DGAIEK 129

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
           +          +YM          P          G E   Q         + V+  +G 
Sbjct: 130 VYSLVRENPDRYYMP----DQFNNPANPAAHHFGTGPEIFEQ----TEGKVNTVVVTLGT 181

Query: 234 GSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDG 292
              A+G+       +  + ++GVEP                     Y G +   ++    
Sbjct: 182 TGTAMGILQAMKERDPAIRVVGVEP---------------------YPGHRVQGLKNMKE 220

Query: 293 QIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESS 352
                      LD                   + I D++A E  + L   EGI   + S 
Sbjct: 221 SYVPGIFDRHALD-----------------QIIHIKDEDAFEMARRLAREEGIFTGMSSG 263

Query: 353 HALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILK 392
            A+A A+++  E  +   + V+   G           +L+
Sbjct: 264 AAMAIAVRVAEEMREGIVVAVLPDGGDRYLSTNLFTTLLE 303


>UniRef50_Q3A093 L-threonine ammonia-lyase n=9 Tax=Desulfuromonadales
           RepID=Q3A093_PELCD
          Length = 415

 Score =  205 bits (523), Expect = 2e-51,   Method: Composition-based stats.
 Identities = 71/340 (20%), Positives = 117/340 (34%), Gaps = 42/340 (12%)

Query: 55  RPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQ 114
           R T L      +      LY K E+L   G+ K                   +    AG 
Sbjct: 19  RRTELIHSHFFSEQIGLPLYFKCENLQRSGSFKVRGAFHFMARQPAQRLAAGVVTASAGN 78

Query: 115 HGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEAL 174
           H    AL++A LG+   + M       +       R  GAEV+          DA  EAL
Sbjct: 79  HAQGVALSAARLGVAATVVMPENTPLAKM---QATRGYGAEVVL---HGTVFDDAQEEAL 132

Query: 175 RDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGG 234
           R      +  H +L     P  +P ++   Q  IG E    + +      D ++A VGGG
Sbjct: 133 R-----LQHTHDLL--YVPPFDHP-LIMAGQGTIGLEIIEDLPD-----VDTLLAPVGGG 179

Query: 235 SNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQ 293
                +          V +IGVE            A L   R G   G            
Sbjct: 180 GLISEVATAIKALRPTVRVIGVE-------AAAAPAALLSRRQGHIVG------------ 220

Query: 294 IEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSH 353
           +  ++S++ G+    +G Q   +      + V++ +++  +A   L     ++     + 
Sbjct: 221 LSGAHSLADGIALKRIGEQTFPVIEALVDELVTVNEEQIAQAIVALMEKTRLVVEGAGAV 280

Query: 354 ALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
            LA  L   R       + +  LSG G+ D+ T+  ++  
Sbjct: 281 GLAALLHAARPLARGRTVCL--LSG-GNIDVQTIAQVVDR 317


>UniRef50_C1ZHQ7 Threonine dehydratase n=4 Tax=Bacteria RepID=C1ZHQ7_PLALI
          Length = 320

 Score =  205 bits (522), Expect = 2e-51,   Method: Composition-based stats.
 Identities = 62/340 (18%), Positives = 112/340 (32%), Gaps = 38/340 (11%)

Query: 48  LLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEII 107
            +  +  R T +     +       LY K E+L   G+ K         L +       +
Sbjct: 16  RIAPWIHR-TPVLTSHTLNKLCEAELYFKCENLQRTGSFKVRGAHNATFLLEEELAHNGV 74

Query: 108 AETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLK 167
               +G H  A ALA    G+   I M     + +   +   R +G  VI     +A  +
Sbjct: 75  VTHSSGNHAAALALAGKNRGVPAFIVMPGNAPKAK---IESTRRLGGNVILCEPTAAARQ 131

Query: 168 DACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAV 227
            A ++ +++            GT   P     IV   Q     E   ++        DA+
Sbjct: 132 MAADQLVQE----------TGGTLIHPFDDLRIV-AGQGTCALELLDEVPHL-----DAI 175

Query: 228 IACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMM 287
           +A VGGG    G               +    H   T            G     ++ + 
Sbjct: 176 VAPVGGGGLLSGTA-------------IVAHHHSQATDHQCLTFGAEPTGADDAARS-LA 221

Query: 288 QTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIP 347
                 +    +I+ GL    +G     +     A   +++D+E L+A + L     I+ 
Sbjct: 222 TGVRQPMNSPQTIADGLRTA-LGENTFPIIQQHVAAIGTVSDEEILKATRLLWEVMKIVV 280

Query: 348 ALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTV 387
               +   A  L+     P + + + + LSG G+ D+  +
Sbjct: 281 EPSGAVPFAAVLQ--NRLPLRGKKVGLILSG-GNLDLDRL 317


>UniRef50_C6A2V6 Threonine dehydratase n=1 Tax=Thermococcus sibiricus MM 739
           RepID=C6A2V6_THESM
          Length = 321

 Score =  205 bits (521), Expect = 3e-51,   Method: Composition-based stats.
 Identities = 70/355 (19%), Positives = 127/355 (35%), Gaps = 49/355 (13%)

Query: 46  NDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE 105
            ++      R T L     ++   N  +YLK E+    G+ K   V  + L      K  
Sbjct: 11  AEMRIRDYIRETPLDYSPFLSQKGNANVYLKLENFQLTGSFKIRGVFNKLLSLSEEEKKR 70

Query: 106 IIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFR----MRLMGAEVIPVHS 161
            I    +G HG A A AS  L L   +++       +  ++ +    +R  G + +    
Sbjct: 71  GIVTASSGNHGAAFAYASNFLNLNGIVFLPENASPAKIQDIKQYNVELRFYGNDTVKTEI 130

Query: 162 GSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREG 221
                        R+++   E  +        P+  P  V   Q  IG E + Q+     
Sbjct: 131 F-----------ARNFAEEQEMIY------VPPYNDPK-VIGGQGTIGVELEKQL----- 167

Query: 222 RLPDAVIACVGGGSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYF 280
              DAV+  VGGG    G+      +  +V +IGV+P    +        +K G++    
Sbjct: 168 GKIDAVLVPVGGGGLISGIAGYLKEKMKDVEIIGVQPENSAVMYY----SIKAGKILELE 223

Query: 281 GMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLC 340
                   T  G  ++S +                L      D++ ++++E  E+   + 
Sbjct: 224 SKPTLADGTAGGIEKDSIT--------------FELCRKYVDDFILLSEEEIAESILLML 269

Query: 341 LHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKARG 395
               ++    ++ ++A  LK       K   +V+ LSG     +  +  ILKA G
Sbjct: 270 EKHHMLIEGAAALSVAAYLKEAPRFKGKN--VVLILSGCR-ISLDRLRKILKAFG 321


>UniRef50_A7I331 Threonine dehydratase n=54 Tax=Bacteria RepID=A7I331_CAMHC
          Length = 537

 Score =  204 bits (519), Expect = 4e-51,   Method: Composition-based stats.
 Identities = 52/294 (17%), Positives = 90/294 (30%), Gaps = 41/294 (13%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T+      ++      +YLK+E+L   GA+K      +        K   +    AG H 
Sbjct: 155 TSCDLAPKLSEIYGAKIYLKKENLQTTGAYKIRGAFNKIAHLSEDDKKRGVVAASAGNHA 214

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD 176
              A+++   G+K  I M           V   + +GAEVI          +A   AL+ 
Sbjct: 215 QGVAISAKHFGVKATIVMPEATP---LLKVAGTKSLGAEVIL---KGDNFDEAYAYALKY 268

Query: 177 WSGSYETAHYMLGTAAGPHPYPT-IVREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
                +            HP+    V+  Q  I  E    + +      D V+  VGGG 
Sbjct: 269 TKEHDK---------IFVHPFDDEFVQAGQGTIALEMLESVPDL-----DYVVLPVGGGG 314

Query: 236 NAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQI 294
              G+ +          +I V   G                           +  +    
Sbjct: 315 LISGVASYIKQVNPECKVIAVGAKGAPAMHDS-------------------FLAKKVINS 355

Query: 295 EESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPA 348
           +   +I+ G+           +      ++V + D+E   A   L   + II  
Sbjct: 356 KSVRTIADGIAVRDASEITLKIILETVDEFVQVDDNEIANAILYLLEQQKIIVE 409


>UniRef50_Q6MP14 Threonine ammonia-lyase n=1 Tax=Bdellovibrio bacteriovorus
           RepID=Q6MP14_BDEBA
          Length = 403

 Score =  203 bits (516), Expect = 1e-50,   Method: Composition-based stats.
 Identities = 71/354 (20%), Positives = 119/354 (33%), Gaps = 45/354 (12%)

Query: 42  QAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRM 101
             +  +LLK+    PT ++   + +    + +YLK E+    G+ K      +       
Sbjct: 8   IQKARELLKDIIC-PTEMSHSISASNLLKSEVYLKFENTQRTGSFKFRGAYNKISNLTAD 66

Query: 102 GKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS 161
            K   +  + AG H    AL++ L G+K  I M       ++      R  GA V+    
Sbjct: 67  EKARGVVASSAGNHAQGVALSAKLAGVKSTIVMPETASISKA---SATRDYGANVVL--- 120

Query: 162 GSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREG 221
                 +  +EA        +   Y   T   P+  P  V   Q  IG E   ++ +   
Sbjct: 121 ----KGEIYDEAFEHAQKLEKEHGY---TFVHPYQDP-YVIAGQGTIGIEILEKVPDL-- 170

Query: 222 RLPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYF 280
              D VI  +GGG    G+          + +IGV+                        
Sbjct: 171 ---DTVIVPIGGGGLISGVALAVKAINPKIRVIGVQSDRSP------------------- 208

Query: 281 GMKAPMMQTEDGQIEESYSISAGLDFPSVGP-QHAYLNSTGRADYVSITDDEALEAFKTL 339
           GM     +    QI+ + +I+ G+   +          S      V+++DDE  EA   L
Sbjct: 209 GMAHLYNKQPLSQIKRAATIADGIAIKNPSQVMLDSFISKYVDQVVTVSDDEIAEAIVFL 268

Query: 340 CLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
                 +         A     M    D  +   V +SG G+ D+  V  I+  
Sbjct: 269 MERAKTVAEG---SGAAAMAAAMSRGLDLGKKTCVIISG-GNIDLNIVSKIIDR 318


>UniRef50_Q4LEC5 Threonine synthase n=1 Tax=uncultured crenarchaeote 10-H-08
           RepID=Q4LEC5_9CREN
          Length = 414

 Score =  202 bits (515), Expect = 1e-50,   Method: Composition-based stats.
 Identities = 70/359 (19%), Positives = 124/359 (34%), Gaps = 25/359 (6%)

Query: 35  AQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTT-LYLKREDLLHGGAHKTNQVLG 93
             +  E            +   T L   Q +        L+LK E      + K   +  
Sbjct: 58  VWRYWELIPVDQRYASPLSEGNTPLLHAQRLGGELGVKRLFLKDETRNPTASFKDRAMAV 117

Query: 94  QALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMG 153
            A  A  MG+ +++    +G    + A  SA LGL+C  ++       ++    ++ L G
Sbjct: 118 GAAKAVEMGRRDVVIA-SSGNAASSLAAYSASLGLRCTAFVPEDVAMGKA---SQLLLYG 173

Query: 154 AEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETK 213
           A V+ V           +  ++      E   Y   +     P+     E  + I  E  
Sbjct: 174 ARVLRVKQVEEGRDPTVDLMMQ---TVKELGWYPCPSF---GPFNPYQVEGPKTIVYEMV 227

Query: 214 AQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKH 273
            Q+      +PD V    G G  A G++        +GLI   P    ++   +   ++ 
Sbjct: 228 EQM---GWGVPDFVFIPTGSGCLATGIWKALKELRLLGLIESYPKLVPVQPSGNMPLVRA 284

Query: 274 GRVGIYFGMKAPMMQTEDGQIEESYSISAGL--DFPSVGPQHAYLNSTGRADYVSITDDE 331
              G  F    P         +   SI++GL   +P  G        T     V++ +DE
Sbjct: 285 ILQGKRFEEVEPE--------KWPKSIASGLLDPYPWDGDAAMEGVRTTGGTAVAVEEDE 336

Query: 332 ALEAFKTLCLHEGIIPALESSHALAHALKMMREN-PDKEQLLVVNLSGRGDKDIFTVHD 389
             EA K L   EG+      +  +A   K++ +   +    +VV ++  G K+   V  
Sbjct: 337 IREAVKKLARLEGVFAEPSGAVGVAAVQKLLEQGVVEASDTVVVLVTASGLKEPEKVAS 395


>UniRef50_O94634 Threonine dehydratase, mitochondrial n=5 Tax=cellular organisms
           RepID=THDH_SCHPO
          Length = 600

 Score =  202 bits (514), Expect = 2e-50,   Method: Composition-based stats.
 Identities = 80/369 (21%), Positives = 121/369 (32%), Gaps = 40/369 (10%)

Query: 28  LEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHK 87
           + +  +     P++             + T LTK   I+  T   +YLKREDL    + K
Sbjct: 85  IPKEMLLPDGTPDYLRLTLTSNVYEVIKETPLTKGVVISESTGVPVYLKREDLTPVFSFK 144

Query: 88  TNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVF 147
                 +     +      +    AG H    A ++  LG+K  I M     E +  NV 
Sbjct: 145 IRGAHNKMASLDKQSLKNGVIACSAGNHAQGVAYSARTLGVKATIVMPQNTPEIKWRNV- 203

Query: 148 RMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRM 207
             + +GA V+      A    A  E  R                  P   P  V   Q  
Sbjct: 204 --KRLGANVLL---HGANFDIAKAECARLAKEQN-------LEVIHPFDDP-YVIAGQGT 250

Query: 208 IGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGE 266
           IG E   QI     R  DA+   VGGG    G+         +V +IGVE      +   
Sbjct: 251 IGLEILHQID---LRKLDAIYCAVGGGGLIAGIATYVKRIAPHVKVIGVET----FDADA 303

Query: 267 HGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVS 326
               LK  +                  ++E    + G     VG +   L S    D V 
Sbjct: 304 LKKSLKDKKRV---------------TLKEVGLFADGTAVKLVGEETFRLVSKNIDDVVL 348

Query: 327 ITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLL--VVNLSGRGDKDI 384
           +  DE   A K + L    +     + A+A   + + ++  K      V  LSG  + D 
Sbjct: 349 VDKDEICAAIKDVFLDTRSVVEPSGAMAVAGMKRYVAKHKPKNPNAAQVCILSGA-NMDF 407

Query: 385 FTVHDILKA 393
             +  I + 
Sbjct: 408 DRLRFIAER 416


>UniRef50_B5FEL5 Threonine synthase n=2 Tax=Vibrio fischeri RepID=B5FEL5_VIBFM
          Length = 376

 Score =  202 bits (514), Expect = 2e-50,   Method: Composition-based stats.
 Identities = 69/377 (18%), Positives = 132/377 (35%), Gaps = 39/377 (10%)

Query: 18  PQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKR 77
           PQ        +E  F   +    F  + +D+   +    T L +       +   + +K 
Sbjct: 31  PQTSFSKKDLIENEFTPRRYSSAFPVKKDDINITFNEAITPLCQA----EISGNPILVKL 86

Query: 78  EDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAK 137
           + L   G+ K              G T  IAE  +G  G A A  +A   ++C I++ A 
Sbjct: 87  DSLQPTGSFKDRGASLVINYLNNHGITS-IAEDSSGNGGSAYAGYAAKGKMQCNIFVPAG 145

Query: 138 DVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPY 197
             + +     + RL GA  I V      +  A  E     S     +HY+       H +
Sbjct: 146 TSKGK---TTQTRLYGANCIEVEGAREDVALAAIE-----SSVTHGSHYVG------HNW 191

Query: 198 PTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEP 257
             +  E  + I  E   Q      + PD  +   G GS   G +  F      G I   P
Sbjct: 192 HPLFIEGVKSIAYEIWEQCRY---KAPDNFVVPAGNGSLLAGAYIGFSELLKGGEISKLP 248

Query: 258 GGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYL- 316
              GI++      ++                 ++  I    +I+ G+        +  + 
Sbjct: 249 RLFGIQSESIQPFVQTFN-------------NKEINITSENTIAEGIKIKRSSRMNEIVQ 295

Query: 317 -NSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDK-EQLLVV 374
                  +++S+++ +   A K +   +G      S+ A A   ++++    K ++L V 
Sbjct: 296 FVKETNGNFISVSEQQIQSALKEMGA-QGYFIEPTSATAFAGIAQLIKTQEIKPDELTVG 354

Query: 375 NLSGRGDKDIFTVHDIL 391
            ++G G K   ++  ++
Sbjct: 355 VVTGNGLKATNSIEHLI 371


>UniRef50_P50867 Cysteine synthase n=103 Tax=cellular organisms RepID=CYSK_EMENI
          Length = 370

 Score =  202 bits (513), Expect = 2e-50,   Method: Composition-based stats.
 Identities = 65/355 (18%), Positives = 112/355 (31%), Gaps = 51/355 (14%)

Query: 53  AGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG---KTEIIAE 109
           A   T L + + ++  T + +  K E    GG+ K    L     A+  G       + E
Sbjct: 39  AIGNTPLIRLKRLSEETGSNILAKAEFQNPGGSVKDRAALYVVKDAEERGLLKPGGTVVE 98

Query: 110 TGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDA 169
             AG  G+  A      G K  IYM     + +   +  +RL+GAEV PV + +    + 
Sbjct: 99  GTAGNTGIGLAHVCRSKGYKLVIYMPNTQSQGK---IDLLRLLGAEVYPVPAVAFDNPEN 155

Query: 170 CNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIA 229
            N   R  + S + A +               R      G E  AQ     G   DA   
Sbjct: 156 YNHKARRHAESLDNAVWT-----NQFDNTANRRAHIETTGPEIWAQ----TGGKLDAFTC 206

Query: 230 CVGGGSNAIGMFADFINET--NVGLIGVEPGGHGIETGEHGA------PLKHGRVGIYFG 281
             G G    G+       +   V     +P G  + +                  GI  G
Sbjct: 207 STGTGGTLAGITYYLKQASGGRVKSFLADPPGSVLHSYIQSGGKLVERSGSSITEGIGQG 266

Query: 282 MKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCL 341
                +Q + G ++ S +I                           +D++ +E       
Sbjct: 267 RITDNLQPDVGTLDGSLNI---------------------------SDEKTIEMIYRCLD 299

Query: 342 HEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGR-GDKDIFTVHDILKARG 395
            EG+     S+  +  A ++  +      ++ +   G     D       L+++G
Sbjct: 300 EEGLYLGASSALNVVAAKEVAEKLGKGSTVVTILADGAYRYADRLFSKSWLESKG 354


>UniRef50_B0VGY7 Putative threonine synthase n=1 Tax=Candidatus Cloacamonas
           acidaminovorans RepID=B0VGY7_9BACT
          Length = 392

 Score =  201 bits (512), Expect = 4e-50,   Method: Composition-based stats.
 Identities = 64/320 (20%), Positives = 118/320 (36%), Gaps = 33/320 (10%)

Query: 72  TLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCR 131
            L++K + L   G++K          A + G  EI+     G    + A   A  GLK  
Sbjct: 102 KLWIKFDGLNPSGSYKDRASQLVVADALQKGIKEIVTA-STGNAACSLACLGASAGLKVV 160

Query: 132 IYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTA 191
           I+            + ++++  AE+  +        DA   AL          H  +   
Sbjct: 161 IFAPQNAP---PAKLIQIQVHNAELHKIDGSYD---DAFKAALEYT-----KTHNCMCRN 209

Query: 192 AGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVG 251
            G HP   +  + ++  G E   Q      ++PD ++  VG G    G++  F++    G
Sbjct: 210 TGYHP---LTIDGKKSAGIEIYVQ---NGYKVPDWIVIPVGDGVILTGIYKAFLDLKKAG 263

Query: 252 LIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGP 311
           +    P    ++     A   +   GIY   + P+            +I+  +   +   
Sbjct: 264 ITEKMPHLLCVQAESSDAITSYWETGIYHDAENPI------------TIADSIKVKTPAL 311

Query: 312 QHAYLNSTGRAD--YVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKE 369
            H  + +    D   + ++D E  EA   L    G+     SS  LA   K++  +  K+
Sbjct: 312 AHWSVKALKETDGKCIRVSDKEIQEAQLELAKETGVFSEPSSSATLAGLKKVVNHSWLKD 371

Query: 370 -QLLVVNLSGRGDKDIFTVH 388
            + +V+ ++G G KD   V 
Sbjct: 372 AKDIVLLITGHGLKDPGAVK 391


>UniRef50_Q2PGG3 Serine racemase n=18 Tax=cellular organisms RepID=Q2PGG3_ARATH
          Length = 331

 Score =  201 bits (511), Expect = 4e-50,   Method: Composition-based stats.
 Identities = 69/370 (18%), Positives = 133/370 (35%), Gaps = 45/370 (12%)

Query: 28  LEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHK 87
           +E        D     + +D +K Y  R T +   +++ + +  +L+ K E L  GGA K
Sbjct: 1   MEANREKYAADILSIKEAHDRIKPYIHR-TPVLTSESLNSISGRSLFFKCECLQKGGAFK 59

Query: 88  TNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVF 147
                   L        + +    +G H  A +LA+ + G+   I +     + +  NV 
Sbjct: 60  FRGACNAVLSLDAEQAAKGVVTHSSGNHAAALSLAAKIQGIPAYIVVPKGAPKCKVDNVI 119

Query: 148 RMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRM 207
           R    G +VI   +  ++ ++  ++ L++            G+          +   Q  
Sbjct: 120 R---YGGKVIWSEATMSSREEIASKVLQE-----------TGSVLIHPYNDGRIISGQGT 165

Query: 208 IGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGE 266
           I  E   QI E      DA++  + GG    G+     + + ++ +I  EP G       
Sbjct: 166 IALELLEQIQEI-----DAIVVPISGGGLISGVALAAKSIKPSIRIIAAEPKGADDAAQS 220

Query: 267 HGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVS 326
             A                    +   +  + +I+ GL   S+G     +      D V+
Sbjct: 221 KVA-------------------GKIITLPVTNTIADGLR-ASLGDLTWPVVRDLVDDVVT 260

Query: 327 ITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPD---KEQLLVVNLSGRGDKD 383
           + + E +EA K       +      +  LA  L     N       + + + LSG G+ D
Sbjct: 261 LEECEIIEAMKMCYEILKVSVEPSGAIGLAAVLSNSFRNNPSCRDCKNIGIVLSG-GNVD 319

Query: 384 IFTVHDILKA 393
           + ++ D  K+
Sbjct: 320 LGSLWDSFKS 329


>UniRef50_C1TP96 Threonine synthase n=1 Tax=Dethiosulfovibrio peptidovorans DSM
           11002 RepID=C1TP96_9BACT
          Length = 378

 Score =  201 bits (511), Expect = 4e-50,   Method: Composition-based stats.
 Identities = 73/342 (21%), Positives = 118/342 (34%), Gaps = 37/342 (10%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T L               +K + L   G++K   +       + +G T +I E  +G  G
Sbjct: 72  TPLIPV----ELDGVKPLVKMDFLCPTGSYKDRGISVLVSRLRELGITSLI-EDSSGNAG 126

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD 176
            A A      GL C +Y+       +     ++   GAE+I V        DA   A R+
Sbjct: 127 AAMAAYCTAGGLNCSVYVPDYTSAGKCV---QIEAYGAELIRVPGTREDTTDAAMAAARE 183

Query: 177 WSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSN 236
                        T  G H +     E  +    E   Q+       PD ++  +G GS 
Sbjct: 184 -------------TYYGSHNWSPWFVEGVKTFAYEIWEQL---GWTAPDHLVLPLGQGSL 227

Query: 237 AIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEE 296
            +G +       ++GLI   P  HG+++       +    G+      P   T+   + E
Sbjct: 228 VLGAYRALSELRDMGLIDHIPKIHGVQSANCAPLARAYESGLD----VPENITKAETVAE 283

Query: 297 SYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALA 356
             S +  L     G +        R   V++ +   +E    L    GI     S+  + 
Sbjct: 284 GISSATPLR----GAEVLEAVKRSRGSIVAVDEKPIVEGIFALASR-GIYVEPTSAVVVP 338

Query: 357 HALKMMRENP-DKEQLLVVNLSGRGDKDIFTVHDILKARGEI 397
              K+M      K +  VV LSG G K       IL+ R +I
Sbjct: 339 GISKLMESGAISKGETTVVFLSGSGLK---ATDKILELRRKI 377


>UniRef50_B8P126 Predicted protein n=6 Tax=cellular organisms RepID=B8P126_POSPM
          Length = 509

 Score =  200 bits (510), Expect = 5e-50,   Method: Composition-based stats.
 Identities = 79/386 (20%), Positives = 127/386 (32%), Gaps = 42/386 (10%)

Query: 16  YVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYL 75
           + P+ L     +L +  +     P++             + T L  C N++A     ++L
Sbjct: 12  HAPEPLPYP--RLSKHHLLPSGTPDYLRLILTSKVYEVLKETPLFYCPNLSARFGNQIWL 69

Query: 76  KREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMG 135
           KREDL    + K               + + +    AG H    AL+ + LG+ C I M 
Sbjct: 70  KREDLQEVFSFKIRGAYNFMANISEEERWKGVVTCSAGNHAQGVALSGSKLGIPCTIVMP 129

Query: 136 AKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPH 195
                 +  NV R   +GA+V+          +A  E  R  S          G    P 
Sbjct: 130 KGTPAIKVRNVSR---LGAKVVLY---GQDFDEAKAECARLASAH--------GLIFVPP 175

Query: 196 PYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFIN--ETNVGLI 253
               +V   Q  IG E   Q+ +      DA+ A VGGG    G+          +  +I
Sbjct: 176 YDDPLVVAGQGTIGMEILKQMSDA--ETLDAIFAGVGGGGLISGILEYVKRIGSPDTKVI 233

Query: 254 GVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQH 313
           GVE     ++       L+ G                   +EE    S G     VG + 
Sbjct: 234 GVET----VDGDAMARSLEKGERV---------------TLEEVGPFSDGTAVKIVGAEP 274

Query: 314 AYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMM--RENPDKEQL 371
             +      + V   +DE   A K +      I     + ALA   + +   +    ++ 
Sbjct: 275 FRICKQLLDEIVKTDNDEICAAIKDVFEETRSITEPAGALALAGLKRYILNNQLVGAQKK 334

Query: 372 LVVNLSG-RGDKDIFTVHDILKARGE 396
            V  +SG   + D           GE
Sbjct: 335 FVAVVSGANMNFDRLRFVAERAELGE 360


>UniRef50_C6Q2L0 Threonine dehydratase n=1 Tax=Clostridium carboxidivorans P7
           RepID=C6Q2L0_9CLOT
          Length = 404

 Score =  200 bits (510), Expect = 5e-50,   Method: Composition-based stats.
 Identities = 69/357 (19%), Positives = 122/357 (34%), Gaps = 42/357 (11%)

Query: 42  QAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRM 101
             +  + +K    R T +      +   N  +YLK E+    GA K      + +     
Sbjct: 8   IKKAQENIKE-VVRKTPMFHTSTFSKKCNCNVYLKCENKQKTGAFKLRGAYNKLVNLTEE 66

Query: 102 GKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS 161
            K   +  + AG H    A A+    +K  I M     + +   V   +  GAEVI    
Sbjct: 67  EKKRGVIASSAGNHAQGVAFAATSFNVKSTIVMPLTAPQAK---VAATKGYGAEVIQAGQ 123

Query: 162 GSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREG 221
                 D   E  ++             T   P      V   Q  I  E    + E   
Sbjct: 124 VYDECHDKAVEVQKETGA----------TFLEPFNDID-VMAGQGTIALEMLEDLPEA-- 170

Query: 222 RLPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYF 280
              D ++  +GGG    G+     + + ++ ++GVEP           A L+ G+V    
Sbjct: 171 ---DVIVVPIGGGGLISGIAVAAKSIKPSIRIVGVEPEIVP----SAKAALEKGKVTTVP 223

Query: 281 GMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLC 340
           G K               S++ G+   ++G +          + V+I++DE   A   + 
Sbjct: 224 GAK---------------SLADGISVSTLGDECFKYIQKYVDEVVTISEDEIAHAMFQIM 268

Query: 341 LHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKARGEI 397
               +I     +  LA  L    +  + + ++ +  SG G+ DI T   I++     
Sbjct: 269 ERNKLIVEGSGAAPLAALLAKKIDGIEGKNVIALV-SG-GNADIATTAKIIERELVF 323


>UniRef50_C1AEM2 Cystathionine beta-synthase n=1 Tax=Gemmatimonas aurantiaca T-27
           RepID=C1AEM2_GEMAT
          Length = 479

 Score =  200 bits (510), Expect = 6e-50,   Method: Composition-based stats.
 Identities = 65/339 (19%), Positives = 110/339 (32%), Gaps = 42/339 (12%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG---KTEIIAETGAG 113
           T L     +  G  T L  K +    GG+ K    L      +  G       I E  +G
Sbjct: 34  TPLIHLARVAKGIRTPLLGKADFFNPGGSVKDRIGLPMIEAHEAAGTLKPGGTIVEATSG 93

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSG--SATLKDACN 171
             GV  A+A+AL G +C   M  K  + +   V  ++  GAEVI   +       ++   
Sbjct: 94  NTGVGLAIAAALKGYRCIFTMPDKMSQEK---VRLLKAFGAEVIITPTAVPPDHPQNYVQ 150

Query: 172 EALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACV 231
            A R    +           AG    P          G E   Q   R        +A  
Sbjct: 151 MAKRIVKETPGAV------LAGQFENPANPAAHVATTGPEIWEQTQGRI----THFVASA 200

Query: 232 GGGSNAIGMFADFI-NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTE 290
           G G    G+         N+ +I  +P G  +      A L   +   +       ++  
Sbjct: 201 GTGGTITGVARYLKSKNPNIKIIAADPMGSVL------AELWRSKGEGHPTGAPYKVEGV 254

Query: 291 DGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALE 350
                                    L+ +   +++S++D +A    + L   EGI     
Sbjct: 255 GQDCVPET-----------------LDMSVIDEFISVSDKDAFSMARRLTREEGIFVGGS 297

Query: 351 SSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHD 389
           +      AL + R   D E ++V  L   G++ +  +++
Sbjct: 298 AGLIAHAALNVARRLDDPEAMVVTFLCDTGERYLSKLYN 336


>UniRef50_D2S288 Threonine dehydratase n=2 Tax=Haloterrigena turkmenica DSM 5511
           RepID=D2S288_9EURY
          Length = 414

 Score =  200 bits (508), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 63/360 (17%), Positives = 114/360 (31%), Gaps = 43/360 (11%)

Query: 33  VSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVL 92
            S  +  + +   +        + T + +  ++    +  +YLK E L   G+ KT    
Sbjct: 8   ESLVQYADIERARDRFDDETVVKRTPVERSTSLGEMVDAEVYLKMEHLQWTGSFKTRGAY 67

Query: 93  GQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLM 152
            +   A   G  E +A   AG H    ALA+   G    I M     + +   +   R  
Sbjct: 68  NKIRQAVDDGADEFVAA-SAGNHAQGVALAATKCGANSTIVMPTHAPQAK---IDATRSY 123

Query: 153 GAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEET 212
           GA V  V       ++A   A    + +              +  P IV   Q  +G E 
Sbjct: 124 GAAVELV---GQDFQEAMAYAQDYAADNDVE-------FVHAYDDPNIV-AGQGTLGIEI 172

Query: 213 KAQILEREGRLPDAVIACVGGGSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPL 271
                +      D V+  +GGG    G+     +      ++GV+  G           L
Sbjct: 173 HEDCPD-----VDTVVVPIGGGGLISGVATALDHLSPETRVVGVQAEG----AATVHESL 223

Query: 272 KHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDE 331
             G                     E  +I+ G+    +      L      + V+++D E
Sbjct: 224 DKGIPVTLD---------------EVDTIADGIATGGISDLTLNLIEDHVDEVVTVSDAE 268

Query: 332 ALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDIL 391
              A   L      +       A + A  +  +     + ++  L G G+ D+  +  +L
Sbjct: 269 IANAILLLLERAKQVVEGA--AAASVAAVLSDQLDVSGETVMPVLGG-GNLDMTMLQTVL 325


>UniRef50_B5E900 Cysteine synthase n=1 Tax=Geobacter bemidjiensis Bem
           RepID=B5E900_GEOBB
          Length = 354

 Score =  199 bits (507), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 64/334 (19%), Positives = 112/334 (33%), Gaps = 57/334 (17%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG---KTEIIAETGAG 113
           T + +  ++       +  K E    GG+ K        L A+  G     ++I E  +G
Sbjct: 7   TPVAEIYSLCKNPAVRIVAKLEGNNPGGSVKDRPARQMILAAEASGELTPDKVILEPTSG 66

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
             G+A A+ +A  G + ++ M A            +   GAE++    G      A   A
Sbjct: 67  NTGIALAMIAAARGYRIKLVMPAC---VSVERRSVLEAYGAEIVLSP-GCEATDGAIRLA 122

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
            +  +      +         +  P  V    +  G E   Q     G     V+A +G 
Sbjct: 123 HKILAEDPAKYYMP-----NQYANPNNVLAHYKTTGPEIWHQ----TGGEVTHVVAGMGT 173

Query: 234 GSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDG 292
               +G+ + F   + +V ++GVEP                       G K   ++    
Sbjct: 174 SGTLMGLASYFKEVKPSVQVVGVEPTL---------------------GHKIQGLKNMKE 212

Query: 293 QIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESS 352
            I       A                      + + DD+A E  + L  HEGI   +   
Sbjct: 213 AIVPPIYDCAA-----------------YHRNLVVEDDDAFETARLLAAHEGIFCGMSGG 255

Query: 353 HALAHALKMMRENPDKEQLLVVNLSGRGDKDIFT 386
            A+  AL++  E      ++VV +  RGD+ + T
Sbjct: 256 AAVFGALQLASELSSG--VIVVIVPDRGDRYLST 287


>UniRef50_A8MAW5 Threonine synthase n=1 Tax=Caldivirga maquilingensis IC-167
           RepID=A8MAW5_CALMQ
          Length = 391

 Score =  199 bits (507), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 77/377 (20%), Positives = 139/377 (36%), Gaps = 44/377 (11%)

Query: 20  ILMPA-LRQL-EEAFVSAQKDPEFQAQFNDLLKNYAGRPT---ALTKCQNITAGTNTTLY 74
            LM A L +L ++  +  ++     + ++ LL     R T     T    I+ G     +
Sbjct: 51  SLMEAILAELPKDIKLRYRRRLGVWS-YSQLLPEPKNRVTLNEGGTPLIRISKGL----F 105

Query: 75  LKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYM 134
            K E L   G+ K   +     LAK +G + I+     G    +++   A  GL+  + +
Sbjct: 106 GKFEGLNPTGSFKDRGMAIGVSLAKAIGVSNIVVA-STGNTAASASAYGARAGLRAIVLL 164

Query: 135 GAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGP 194
            +  V R       +   GA ++ +        DA  EA+           +  G A   
Sbjct: 165 PSGKVARGKLAQSII--HGASIMSID---GYFDDALTEAM---------NMFKAGKAYSL 210

Query: 195 HPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIG 254
           +       E Q+ I  E    I     ++PD VI  VG   N   ++  F     +GLI 
Sbjct: 211 NSINAWRLEGQKSIAYEIYEDI-----KVPDNVIVPVGNAGNIYAIWKGFWELMQIGLID 265

Query: 255 VEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHA 314
             P   G++        +  R G           +E  +++E  ++++ +          
Sbjct: 266 KVPRMIGVQAEGASPLYETWRRG----------SSELIEVKEPKTVASAIRIGKPVNWLK 315

Query: 315 YLN--STGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRE-NPDKEQL 371
            L   +      V++ D+E + A   L    GI     S+   A  +K++R      ++ 
Sbjct: 316 ALKAVNNSGGLLVTVNDNEIMIARGRLARR-GIFVEPASASTYAAYIKLIRNSVISNDER 374

Query: 372 LVVNLSGRGDKDIFTVH 388
            V+ L+G G KD  +V 
Sbjct: 375 TVLVLTGHGLKDPDSVK 391


>UniRef50_B9Z0N9 Pyridoxal-5'-phosphate-dependent protein beta subunit n=1
           Tax=Lutiella nitroferrum 2002 RepID=B9Z0N9_9NEIS
          Length = 353

 Score =  199 bits (506), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 66/355 (18%), Positives = 109/355 (30%), Gaps = 39/355 (10%)

Query: 38  DPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALL 97
           D     Q  + L     R T +     +    +  +++K E L   G+ K    L + L 
Sbjct: 32  DIRVIRQAAERLSGQVVR-TPVLNSPMLDGLNDCRIFVKAESLQLTGSFKIRGALNKILS 90

Query: 98  AKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVI 157
                    +    AG HG A A  + L+G    + +       +  N    R  GAE++
Sbjct: 91  MDPKDLHGGVLTYSAGNHGQAVAAGAKLVGCPVVVVLPNTAPAIKVEN---CRWWGAEIV 147

Query: 158 PVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQIL 217
                +   ++  +E  R              T   P      V   Q  +G E   Q+ 
Sbjct: 148 LYDPVTQMREEVMDEIARQRGM----------TFISPFDDFD-VMAGQGTVGLELCEQMK 196

Query: 218 EREGRLPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRV 276
           E  G  PDAV+    GG  A G+               VE  G                 
Sbjct: 197 EL-GEEPDAVVINCSGGGLASGVVTAVSAYYPKAEFYIVEINGAEKMANS---------- 245

Query: 277 GIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAF 336
                    +M     ++    ++  G+  P  G +   +    +   +S  D+EAL A 
Sbjct: 246 ---------IMTGAPQRVTPPLTVMDGIAGPVAGNRTLSVLMQHKVKCLSTNDEEALGAV 296

Query: 337 KTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDIL 391
                   ++     + +LA  L        K   + V  SG G+ D       +
Sbjct: 297 SAAFRMLKLVVEPGGAASLAAVLSKKSHWTGKN--IAVICSG-GNADPDIFSRAI 348


>UniRef50_C7RHX8 Threonine dehydratase n=26 Tax=Bacteria RepID=C7RHX8_ANAPD
          Length = 402

 Score =  199 bits (506), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 63/353 (17%), Positives = 120/353 (33%), Gaps = 47/353 (13%)

Query: 40  EFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAK 99
           E   +  ++L+    + T +     +       LY+K E+L   G+ K      +     
Sbjct: 6   EMIKEAREILEGNIEK-TPIYTASRM----GENLYIKMENLQKTGSFKLRGAFNKIAHLT 60

Query: 100 RMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPV 159
              K + +    AG H    AL++   G+K  I + +     +   +   R  G EVI V
Sbjct: 61  DEQKKKGVISCSAGNHAQGVALSATRQGIKSYICIPSIAPLSK---IEATRGYGGEVIIV 117

Query: 160 HSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILER 219
                T  DA  +A                T   P      V   Q  IG E   Q+ + 
Sbjct: 118 D---GTFDDAQAKAYELQKERD-------LTYVAPFD-DEYVLSGQGTIGLEILDQLPD- 165

Query: 220 EGRLPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGI 278
                  ++  +GGG    G+     +   +V +IGVEP           A         
Sbjct: 166 ----VKYIVVPIGGGGLISGIALAVKSLRPDVKIIGVEPENAASMLASRKA--------- 212

Query: 279 YFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKT 338
                      +   ++ + +++ G+     G     L      + V++++DE   A   
Sbjct: 213 ----------GKIVTLDSANTMADGIAVKKPGEITFDLCEKYVDEIVTVSEDEITNAILR 262

Query: 339 LCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDIL 391
           L     +      + ++A    +  +    +  +   LSG G+ ++ T++ I+
Sbjct: 263 LLEESKVSAEGAGASSVAAV--LSNKYDFSDGKVCAVLSG-GNINVNTIYQII 312


>UniRef50_Q64CL8 Threonine synthase n=1 Tax=uncultured archaeon GZfos1D1
           RepID=Q64CL8_9ARCH
          Length = 358

 Score =  199 bits (505), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 66/332 (19%), Positives = 117/332 (35%), Gaps = 31/332 (9%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T L     +         +K E     G+ K      +   A   G+   +     G  G
Sbjct: 58  TPLVDLTRLMPQAK-KFLVKYEAANPTGSFKDRGSSLEITKAVTWGRKRAVIA-STGNMG 115

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD 176
            + A  +A   ++C+I +       +   + +M+  GAEV      S    DA N A   
Sbjct: 116 SSVAAFAAFAKIRCKIIIPDFVNTAK---IVQMKAYGAEVELT---SGDYADAMNIAENQ 169

Query: 177 WSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSN 236
                E         AG +P+     E  + +G E   Q+     R+PDAVIA +G G+ 
Sbjct: 170 VRSDPE------SFLAGDYPW---RCEGTKTVGFEIADQM---YWRVPDAVIAPIGNGTL 217

Query: 237 AIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEE 296
              ++  F      G+    P   G++  +    ++          +   +   +     
Sbjct: 218 IWSVWKAFKELMITGITDALPLMVGVQAEKCDPVVRAWEE------RTDTIVPIENPRTV 271

Query: 297 SYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALA 356
           + +I+ G     +    A   S G    + +TD+E L A   L  + G+      + + A
Sbjct: 272 ASAIACGAPIDGLLALKAIRESGGI--CIRVTDEEILRARDELGSN-GVFVEPSGAVSFA 328

Query: 357 HALKMMRENPDKEQLLVVNLSGRGDKDIFTVH 388
            A K       K   +V   +G G KD++ + 
Sbjct: 329 GARKTGDLLDQK--TVVCIATGHGLKDMYGIE 358


>UniRef50_B0TBV3 Threonine synthase n=1 Tax=Heliobacterium modesticaldum Ice1
           RepID=B0TBV3_HELMI
          Length = 413

 Score =  199 bits (505), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 63/342 (18%), Positives = 114/342 (33%), Gaps = 28/342 (8%)

Query: 47  DLLKNYAGRPTALTKCQNITAGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE 105
           + + +     T L +   +    +    ++K E      + K        L A   G + 
Sbjct: 74  ERISHLQVGWTPLYRASRLAETLDVADCWVKDEGRNPTASFKDRASAVGVLKAMERGASR 133

Query: 106 IIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSAT 165
            I     G    + A  +A  GL   I++  +  E +   V ++ + GA+V  V      
Sbjct: 134 -ITCASTGNAASSLAGFAAAAGLPASIFVPKRAPEAK---VAQLLVFGAQVFSVQGTYDQ 189

Query: 166 LKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPD 225
             + C  A   +        Y    A   +     + E ++ +  E   Q  ER G  PD
Sbjct: 190 AWELCMAASSHF------GWYNRNCAINAY-----LIEGKKTVALELVEQFRER-GAFPD 237

Query: 226 AVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAP 285
            V+  VG G    G++  F     +G I   P   G++       +   R G        
Sbjct: 238 WVVVSVGDGCTIGGVWKGFKEMQRIGWIEKTPKILGVQAAGCQPFVTAWREGKRLTPCEA 297

Query: 286 MMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGI 345
               +   +    +   GL             +     YV++ D   LEA  TL     +
Sbjct: 298 DTLADSIAVGHPRNFVKGLRA----------VTESGGAYVAVPDQAILEAMTTLARKAAV 347

Query: 346 IPALESSHALAHALKMMREN-PDKEQLLVVNLSGRGDKDIFT 386
                 +  +A   +  R+     + ++ V ++G G KDI +
Sbjct: 348 FGEPAGATGVAGVQEARRQGIIGPDDVVAVIVTGNGLKDIAS 389


>UniRef50_A5V1I5 L-threonine ammonia-lyase n=2 Tax=Roseiflexus RepID=A5V1I5_ROSS1
          Length = 321

 Score =  199 bits (505), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 67/336 (19%), Positives = 110/336 (32%), Gaps = 38/336 (11%)

Query: 56  PTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           PT L +   + A T     LK E+    G+ K    L   L      +   I    +G H
Sbjct: 21  PTPLDESIRLGALTGGRALLKLENTQPTGSFKVRGALNVLLALPHHVRERGIVAASSGNH 80

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
           G A A  +  LG    I++           V  MR  GA+V                  R
Sbjct: 81  GAAVAYGALTLGAPALIFVPEDT---SPVKVDAMRDFGADVRM----YGDDCVVAERYAR 133

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
            ++  +   +        P+  P +V   Q  IG E   QI        DA++  VGGG 
Sbjct: 134 AYATEHGLTY------ISPYNDP-LVIGGQGTIGVELARQI-----DRLDAILVAVGGGG 181

Query: 236 NAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQI 294
              G+       + +V +IG  P           A        +   +   +     G +
Sbjct: 182 LISGIATYMKAVQPDVRIIGCSPINSPAMYESVLA-----GEVVSPPILPTLSDGTAGGV 236

Query: 295 EESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHA 354
           E                    L  T   ++V +++DE   A + +   +  +    +  A
Sbjct: 237 EP-------------DAITLDLCRTLVDEWVLVSEDEIAAAMRLMIETQHTLVEGSAGVA 283

Query: 355 LAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDI 390
           +A  L++  E   K   +V+  S      + TV D+
Sbjct: 284 VAGYLRLKDEMRGKTAAIVICGSNVSLATLRTVIDM 319


>UniRef50_A3DKY8 Transcriptional regulator n=1 Tax=Staphylothermus marinus F1
           RepID=A3DKY8_STAMF
          Length = 436

 Score =  198 bits (504), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 66/346 (19%), Positives = 113/346 (32%), Gaps = 57/346 (16%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T L +  N+    N  +Y K E     G+ +          A   G   ++     G  G
Sbjct: 67  TPLIRSDNLFR--NENIYFKDESRNPTGSFRDRAAALIVSDALDQGAKRLVVA-SDGNMG 123

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD 176
            + A  SA  GL   IY+    V      +  M+  GA+VI       TL        R 
Sbjct: 124 ASIAAYSAKAGLPVTIYVP---VWTDPEKILLMKAYGAKVIVSEEDLDTLLQYVERRAR- 179

Query: 177 WSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSN 236
                +   Y   +         +  E  + IG E   Q     G +P  V   +G G  
Sbjct: 180 -----KEKLYNASSTYNI-----LAMEGLKTIGYEIYLQ----YGGVPSTVYVPLGSGLT 225

Query: 237 AIGMFADFIN-------ETNVGLIGVEPGGHGIETGEHG-APLKHGRVGIYFGMKAPMMQ 288
            + ++  F         +    LIGVE   + + +  HG     +         + P+++
Sbjct: 226 ILSLYHGFSEMHSNNIIDHIPKLIGVETCANPVYSSIHGNPTKCNEEPMPGLYYRKPVLK 285

Query: 289 TEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPA 348
               +I + +                        + + + + +   A K L + EG+   
Sbjct: 286 EYVSEIIDKH-----------------------GETIVVNNKQVYMAAKKLAMEEGLFVE 322

Query: 349 LESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKAR 394
             S+ ALA ALK+        +  ++ L+G G K         + R
Sbjct: 323 PSSAVALAGALKI-----GGTENSIILLTGHGLKSPTPYTRPSRER 363


>UniRef50_A5F498 Threonine dehydratase n=35 Tax=Bacteria RepID=A5F498_VIBC3
          Length = 510

 Score =  198 bits (504), Expect = 3e-49,   Method: Composition-based stats.
 Identities = 72/352 (20%), Positives = 112/352 (31%), Gaps = 44/352 (12%)

Query: 40  EFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAK 99
           E+  Q            T L     ++A     + +KRED     + K            
Sbjct: 10  EYLRQILRSPVYEVANVTPLQTMPRLSARIGNQVQIKREDRQPVHSFKLRGAYNMVSHLT 69

Query: 100 RMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPV 159
              K   +    AG H    AL+   LG+K  I M     + +   V  +R  G EV+  
Sbjct: 70  EAQKAAGVIAASAGNHAQGMALSGTKLGIKTTIVMPRTTPDIK---VEAVRGFGGEVLL- 125

Query: 160 HSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILER 219
               +   +A  EA R              T   P  +P +V   Q  IG E   Q    
Sbjct: 126 --HGSNFDEAKAEAERLSKEQG-------YTFVPPFDHP-LVIAGQGTIGMEMLQQ---- 171

Query: 220 EGRLPDAVIACVGGGSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRVGI 278
                D +   VGGG  A G+          + +I VEP     ++    A L  G+  +
Sbjct: 172 -NGHLDYIFVPVGGGGLAAGVAVLVKQLMPEIQVIAVEPE----DSACLKAALDAGKPVV 226

Query: 279 YFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKT 338
              +                  + G+    +G +   L       +V+++ DE   A K 
Sbjct: 227 LDQV---------------SMFADGVAVKRIGDETFRLCQQYIDGHVTVSSDEICAAVKD 271

Query: 339 LCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSG-----RGDKDIF 385
           +      I     + ALA   K   +   K + L   LSG      G + + 
Sbjct: 272 IFEDTRAIAEPSGALALAGLKKFAEQQQLKGKQLGTVLSGANTNFHGLRYVS 323


>UniRef50_C6HUM2 Cysteine synthase n=1 Tax=Leptospirillum ferrodiazotrophum
           RepID=C6HUM2_9BACT
          Length = 316

 Score =  198 bits (503), Expect = 3e-49,   Method: Composition-based stats.
 Identities = 65/328 (19%), Positives = 106/328 (32%), Gaps = 49/328 (14%)

Query: 53  AGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG---KTEIIAE 109
               T L     I+     T+ +K E    GG+ K    L     A+  G       I E
Sbjct: 19  LIGKTPLVPLSGISFDLGRTILVKLESKNLGGSIKDRPALFMIEDARARGLLAPRAPIVE 78

Query: 110 TGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDA 169
             +G  G+  A    L      I M     +     V  +R +GA V    + +  +  A
Sbjct: 79  ATSGNMGIGLAQIGVLAHHPVTIVMPEGMSQ---ERVSHLRALGATVELTPA-AGGMSAA 134

Query: 170 CNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIA 229
              A  +   S   A             P       R  G E    +    G +PD  ++
Sbjct: 135 IRRA-EEIVSSIHGAFMPR-----QFDNPANPDSHYRTTGPEIVESL----GGVPDGFVS 184

Query: 230 CVGGGSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQ 288
            VG G    G+      +   + +  VEP    + +G  GAP  H   GI  G    +  
Sbjct: 185 GVGTGGTISGVGRFLREKSPEIPVWAVEPESSPVLSG--GAPGPHRIQGIGAGFVPKI-- 240

Query: 289 TEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPA 348
                                      L+    +   ++TD +A+E  + L   EGI+  
Sbjct: 241 ---------------------------LDRKVISRVFTVTDIQAIETARRLAKEEGIMAG 273

Query: 349 LESSHALAHALKMMRENPDKEQLLVVNL 376
           + S   +  A+ + R  P+  +++ V  
Sbjct: 274 ISSGANVFAAIALARTLPEGSRVVTVVC 301


>UniRef50_C3YDM6 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
            RepID=C3YDM6_BRAFL
          Length = 1887

 Score =  198 bits (503), Expect = 4e-49,   Method: Composition-based stats.
 Identities = 63/344 (18%), Positives = 111/344 (32%), Gaps = 49/344 (14%)

Query: 57   TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLA------KRMGKTEIIAET 110
            T +  C+ +       L+ K E+    G+ K                 + + +   +   
Sbjct: 1584 TPIQTCETLDLLAGRRLFFKCENFQRSGSFKFRGAFNAVSRLVSSNPNEPIKRQLHVVGC 1643

Query: 111  GAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDAC 170
             +G +    ALA+ L G+   + M     E +   V      GA ++           A 
Sbjct: 1644 SSGNYACGLALAAKLHGVTAHVIMPNNCPECKKQTVL---SYGANLLQ--REQKDFIPA- 1697

Query: 171  NEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIAC 230
                R        A ++  +    HP    V   Q  +G E   Q+ +      DAVI  
Sbjct: 1698 ----RKQVEDLTGAVFISSS---QHPD---VISGQGTMGLELLQQVPDL-----DAVIMP 1742

Query: 231  VGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQT 289
            VGGG    G+     +    V + G EP        +    L+ G    +          
Sbjct: 1743 VGGGGMLAGVSMVIKSVCPEVRVYGAEPEV----ANQAALSLRTGERSTFSQF------- 1791

Query: 290  EDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPAL 349
                     SI+ GL    +G            D  ++++DE   A + +     ++   
Sbjct: 1792 -------PRSIADGL-VCGIGEVTWTYIRDNVDDIFTVSEDEIKNAMRLVWERMKLVVEP 1843

Query: 350  ESSHALAHAL-KMMRENPDKEQLLVVNLSGRGDKDIFTVHDILK 392
                 +A  L    +      + + V LSG G+ D+  + +ILK
Sbjct: 1844 SGVVGVAAVLCDSFKARAGGCKNVAVILSG-GNVDVQKLPEILK 1886


>UniRef50_C5A2G0 Threonine synthase (ThrC) n=1 Tax=Thermococcus gammatolerans EJ3
           RepID=C5A2G0_THEGJ
          Length = 379

 Score =  198 bits (503), Expect = 4e-49,   Method: Composition-based stats.
 Identities = 68/343 (19%), Positives = 109/343 (31%), Gaps = 35/343 (10%)

Query: 40  EFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAK 99
           +F      L  +     T L K   +       LYLK E +    + K          A 
Sbjct: 50  DFWPLEPALDFSLGEGDTPLVKS-RLGDEFGIKLYLKNETVNPTWSFKDRGTFLAMSYAL 108

Query: 100 RMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPV 159
           + G    +     G    + +  +   GLK +I +     + +   V    + G EVI V
Sbjct: 109 KAGYKT-VGTVSTGNMAASVSAYATRFGLKAKILVSESAGDEKLKAVS---VYGGEVIRV 164

Query: 160 HSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILER 219
           H              R +  S +    +            +  E  + I  E   +I   
Sbjct: 165 HGDYG----------RLYFESLKLGERLGVYFMNS--DNPLRIEGYKSIAFEIAEEIS-- 210

Query: 220 EGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIY 279
               PD ++     G    G+   FI     GLI   P    ++           R G  
Sbjct: 211 ----PDYILIPTSSGGLFRGVAKGFIELYKSGLIEGLPKLIAVQAEGCSPICMAFREGRE 266

Query: 280 FGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTL 339
              +    +T    I   Y        PS       L   G    VS++DDE  +A + L
Sbjct: 267 KVERFENPRTIAKAIANPY-------PPSGNALLKLLREFGWG-CVSVSDDEIRKAQERL 318

Query: 340 CLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDK 382
              EG+     S+  +A   K+    P+  +++ V L+G G K
Sbjct: 319 AR-EGLFVQPASATGIAALEKL--NLPEGAKVVSV-LTGSGLK 357


>UniRef50_Q9GZT4 Serine racemase n=27 Tax=Deuterostomia RepID=SRR_HUMAN
          Length = 340

 Score =  198 bits (503), Expect = 4e-49,   Method: Composition-based stats.
 Identities = 56/348 (16%), Positives = 110/348 (31%), Gaps = 44/348 (12%)

Query: 44  QFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKR--- 100
           +   +    +   T +     +   T   L+ K E     G+ K    L           
Sbjct: 13  EKAHINIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPDAL 72

Query: 101 MGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVH 160
             K + +    +G HG A   A+ L G+   I +     + +      ++  GA ++   
Sbjct: 73  ERKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPDCKK---LAIQAYGASIVYCE 129

Query: 161 SGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILERE 220
               + ++       +            G    P+  P  V   Q  I  E   Q+    
Sbjct: 130 PSDESRENVAKRVTEE----------TEGIMVHPNQEPA-VIAGQGTIALEVLNQVP--- 175

Query: 221 GRLPDAVIACVGGGSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIY 279
             L DA++  VGGG    G+         +V +   EP                      
Sbjct: 176 --LVDALVVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNAD-----------DCYQSKL 222

Query: 280 FGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTL 339
            G   P +           +I+ G+   S+G     +      D  ++T+DE   A + +
Sbjct: 223 KGKLMPNLY-------PPETIADGVK-SSIGLNTWPIIRDLVDDIFTVTEDEIKCATQLV 274

Query: 340 CLHEGIIPALESSHALAHAL-KMMRENPDKEQLLVVNLSGRGDKDIFT 386
                ++    +   +A  L +  +    + + + + LSG G+ D+ +
Sbjct: 275 WERMKLLIEPTAGVGVAAVLSQHFQTVSPEVKNICIVLSG-GNVDLTS 321


>UniRef50_Q01PK6 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit n=1
           Tax=Candidatus Solibacter usitatus Ellin6076
           RepID=Q01PK6_SOLUE
          Length = 339

 Score =  198 bits (503), Expect = 4e-49,   Method: Composition-based stats.
 Identities = 63/349 (18%), Positives = 112/349 (32%), Gaps = 44/349 (12%)

Query: 43  AQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG 102
               + ++    R T +             +Y K E+L  GGA K        L      
Sbjct: 34  RAAAERIR-PLARKTPVFTSAGFDTEAGARVYFKCENLQRGGAFKIRGAANLVLSLPPES 92

Query: 103 KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSG 162
               +    +G H  A+A+A+  +G+   I M     + +       R  GA ++  +  
Sbjct: 93  LARGVVAYSSGNHAQATAIAARHVGVASTIVMPEDAPKSKM---EATRAHGARIVTYNRF 149

Query: 163 SATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGR 222
           + + +      L++             T   P  +P ++   Q     E   +       
Sbjct: 150 TDSREAIAQSILKETGA----------TLIPPFDHP-MIMAGQGTAALELLEET-----G 193

Query: 223 LPDAVIACVGGGSNAIGMFA-DFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFG 281
             DA+IA VGGG    G           V + G EP G      +    +  G       
Sbjct: 194 PLDALIAPVGGGGLLSGCATIAKALHPTVRVFGAEPAG----ANDTFLSMVAGTRIAVH- 248

Query: 282 MKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCL 341
                            +I+ GL  P  G     +        + +++DE   A + L L
Sbjct: 249 ---------------PDTIADGLRSPKPGELTFPVIRELAERILLVSEDEIRAAVRFLLL 293

Query: 342 HEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDI 390
              I+       A+  A  +  + P+  + + V LSG G+ D   +  +
Sbjct: 294 RLKILVEPSG--AVPAAALLFHKLPEGIRSVGVILSG-GNVDFEELARM 339


>UniRef50_Q03HP8 L-threonine ammonia-lyase n=18 Tax=Bacteria RepID=Q03HP8_PEDPA
          Length = 351

 Score =  197 bits (502), Expect = 5e-49,   Method: Composition-based stats.
 Identities = 68/356 (19%), Positives = 130/356 (36%), Gaps = 47/356 (13%)

Query: 42  QAQFNDLLKNYAGRPTALTKCQNITAGT-NTTLYLKREDLLHGGAHKTNQVLGQALLAKR 100
             +  +++K YA R T L K   ++    +  +YLK E++   G+ K      +      
Sbjct: 24  IEEAREVIKKYA-RRTPLVKSMFLSNNVVHGDVYLKLENMQLTGSFKFRGANNKINHLNE 82

Query: 101 MGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVH 160
             K   +    AG H    AL   LLG+K  + M  +  + +       R  GAEV    
Sbjct: 83  EEKQRGVITASAGNHAQGVALTGKLLGIKTTVVMPDEAPQMK---RDATRGYGAEV---D 136

Query: 161 SGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILERE 220
              AT  DA +E +R+ +               P     ++   Q  IG E    +++ E
Sbjct: 137 IHGATFDDA-HEWMRERAEKEGKT------IVDPF-NDALICAGQGTIGLEILEDLVDVE 188

Query: 221 GRLPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIY 279
             +               G+     +   ++ ++GV+                       
Sbjct: 189 TVVVPVGGG-----GLISGIATALKSINPSIHIVGVQSENV------------------- 224

Query: 280 FGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTL 339
            GMKA +   +  +  + ++++ G D  + G     + S    + V ++++E  +A K L
Sbjct: 225 HGMKASVDAGKIVKHHQDFTLADGTDVATPGNITFGIVSKLVDEIVLVSEEEISKAMKDL 284

Query: 340 CLHEGIIPALESSHALAHALKMMRENPD---KEQLLVVNLSGRGDKDIFTVHDILK 392
                ++     + AL  A     +      K++ +V  +SG G+ D+  V  I+ 
Sbjct: 285 MQRTKVVAE--GAGALPTAALEAGKIDPKWTKDKKVVALVSG-GNVDLQRVSQIID 337


>UniRef50_D2Q7L3 TdcB Threonine dehydratase n=10 Tax=Bifidobacterium
           RepID=D2Q7L3_9BIFI
          Length = 435

 Score =  197 bits (500), Expect = 8e-49,   Method: Composition-based stats.
 Identities = 69/381 (18%), Positives = 119/381 (31%), Gaps = 45/381 (11%)

Query: 18  PQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKR 77
           P  +  AL + +E   + Q+D   + +          R T +     ++  T   + LK 
Sbjct: 9   PPTI--ALMEQKEVLKALQRDHAAELKLAAERLAGTARHTEIIPSPTLSEMTGHEILLKP 66

Query: 78  EDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAK 137
           E+L   G+ K      +            I    AG H    A A+   G K  I M   
Sbjct: 67  ENLQVTGSFKIRGAYNKIASLTDEELARGIVTASAGNHAQGVAYAARERGAKATICMPTI 126

Query: 138 DVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPY 197
                   V   +  GA+V+          D  +EA    +   E      G    P   
Sbjct: 127 TP---PLKVDATKAYGADVVL-------HGDVFDEAAAYAAKLSEEQ----GMIFVPPFD 172

Query: 198 PTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEP 257
              V   Q  I  E    +        D V+   GGG  A    A    +  V +IG  P
Sbjct: 173 DYEVICGQGTIALEILEDVPNVT----DIVVPLGGGGLGAGVALAVKTFKPEVRVIGAIP 228

Query: 258 GGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLN 317
            G           L  GRV     +                + + G+     G     L 
Sbjct: 229 EGSPAYKN----SLAAGRVMSADQVV---------------TSAEGVAVKRPGDLPFALL 269

Query: 318 STGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKM-----MRENPDKEQLL 372
           +    D V++++ +  E    +     ++     + +LA    +        + +   ++
Sbjct: 270 NEFLDDIVTVSERDINEMILLMLEKHKLVVEAAGAVSLAALEHLNLRSRKFASAEGPHVV 329

Query: 373 VVNLSGRGDKDIFTVHDILKA 393
           V  +SG G+ D  T+  +++ 
Sbjct: 330 VPIMSG-GNIDTVTMGAVIQK 349


>UniRef50_P35520 Cystathionine beta-synthase n=65 Tax=cellular organisms
           RepID=CBS_HUMAN
          Length = 551

 Score =  196 bits (499), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 59/325 (18%), Positives = 106/325 (32%), Gaps = 43/325 (13%)

Query: 57  TALTKCQNITAGTN--TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE---IIAETG 111
           T + +   I         L  K E    GG+ K    L     A+R G  +    I E  
Sbjct: 87  TPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGDTIIEPT 146

Query: 112 AGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACN 171
           +G  G+  ALA+A+ G +C I M  K    +   V  +R +GAE++   + +       +
Sbjct: 147 SGNTGIGLALAAAVRGYRCIIVMPEKMSSEK---VDVLRALGAEIVRTPTNAR-FDSPES 202

Query: 172 EALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACV 231
                W    E            +   +          +E   Q         D ++A V
Sbjct: 203 HVGVAWRLKNE---IPNSHILDQYRNASNPLAHYDTTADEILQQC----DGKLDMLVASV 255

Query: 232 GGGSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTE 290
           G G    G+      +     +IGV+P G  +   E     +              ++  
Sbjct: 256 GTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQ---------TTYEVEGI 306

Query: 291 DGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALE 350
                 +                  L+ T    +    D+EA    + L   EG++    
Sbjct: 307 GYDFIPT-----------------VLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGS 349

Query: 351 SSHALAHALKMMRENPDKEQLLVVN 375
           +   +A A+K  +E  + ++ +V+ 
Sbjct: 350 AGSTVAVAVKAAQELQEGQRCVVIL 374


>UniRef50_B0T581 Cysteine synthase n=51 Tax=Bacteria RepID=B0T581_CAUSK
          Length = 479

 Score =  196 bits (498), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 70/365 (19%), Positives = 117/365 (32%), Gaps = 42/365 (11%)

Query: 36  QKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQA 95
             DP F               T + + +N+  G    L+LK E+   GG+ K        
Sbjct: 1   MNDPVFALPPVANSALDLIGHTPMMEVRNLDTGP-CRLFLKLENQNPGGSIKDRVARSMI 59

Query: 96  LLAKRMG---KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLM 152
             A+  G       I E  AG  G+  A  + L G K  + +  K    +   +  +R M
Sbjct: 60  EAAEADGSLKPGGTIIEATAGNTGLGLAQVATLKGYKLILIVPDKMAREK---ILHLRAM 116

Query: 153 GAEVIPVHSG-SATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEE 211
           G +V    S       +   +  +  + S   A Y           P      +     E
Sbjct: 117 GVDVRLTRSDVGKGHPEYYQDMAQTLAQSIPGAIY-----VNQFENPANPLAHETTTAPE 171

Query: 212 TKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPL 271
              Q+    G   DA++  VG G    G+   F+ + +     V     G    ++ A  
Sbjct: 172 IFEQM----GGDIDAMVVGVGSGGTLTGVGR-FMAKHSPKTEMVLADPVGSILCDYVATG 226

Query: 272 KHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDE 331
            +G  G      + +++          +    +                     SI+D E
Sbjct: 227 TYGEAG------SWIVEGIGEDFIPVNAEMDFVKH-----------------AYSISDRE 263

Query: 332 ALEAFKTLCLHEGIIPALESSHALAHALKMMRE-NPDKEQLLVVNLSGRGDKDIFTVHDI 390
           +++  + L   EGI+    S   LA AL+  RE    K  + +V  +G            
Sbjct: 264 SVDTARLLLRKEGILAGSSSGTLLAAALRYCREQTEPKRVVTLVCDTGSKYLTKMFNDMW 323

Query: 391 LKARG 395
           L A G
Sbjct: 324 LAAHG 328


>UniRef50_A2ETD5 Threonine synthase family protein n=1 Tax=Trichomonas vaginalis
           RepID=A2ETD5_TRIVA
          Length = 429

 Score =  196 bits (498), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 70/358 (19%), Positives = 123/358 (34%), Gaps = 43/358 (12%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T L       +     L++K E      + K        + AK +GK  ++    +G   
Sbjct: 80  TPLIPVPQDRSPFKIQLWIKDEGREPTASLKDRASALVCVKAKELGK-TVVTTASSGNAA 138

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD 176
            A++   A LGLK  I++ A         V + RL GA V  V        +A   A + 
Sbjct: 139 AATSCMCACLGLKPVIFVPAHAP---PAKVLQNRLYGATVFLVEGVYDRAVEAAMGAAKK 195

Query: 177 WSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILERE---------------- 220
           +      + Y   T   P+       + ++ +  E   Q+                    
Sbjct: 196 Y------SWYNRSTGFNPY-----TIDGKKTVSFEICEQLGGILCPEETKGECSWGKLGK 244

Query: 221 GRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYF 280
              PDA++  VG G+   G+          GLI   P   G++     +        I  
Sbjct: 245 FVAPDAIVVSVGDGNIISGVHKGLKELFAAGLIEKVPKIIGVQAEGSNSVYVCWSQKIDP 304

Query: 281 GMKAPMMQTEDGQIEESYSISAGLDFPSVG-PQHAYL-NSTGRADYVSITDDEALEAFKT 338
                        + E  +++  +  P+   P  A+   +     YV +TD+E L A  T
Sbjct: 305 VNMP---------VCEGSTLADSISCPTPNDPIRAFRAATETNGAYVQVTDEEILAAIPT 355

Query: 339 LCLHEGIIPALESSHALAHALKMMRENPDK-EQLLVVNLSGRGDKDIFTVHDILKARG 395
           +    GI P   ++   A   K  ++   K  + +V+  +G G KDI      ++ + 
Sbjct: 356 MARATGIFPEPAAAAGFAGIFKAEQQGYLKPGEKVVMISTGNGLKDINNATKSMEGKN 413


>UniRef50_A9A5N3 Threonine dehydratase n=3 Tax=Thaumarchaeota RepID=A9A5N3_NITMS
          Length = 402

 Score =  195 bits (497), Expect = 2e-48,   Method: Composition-based stats.
 Identities = 66/355 (18%), Positives = 113/355 (31%), Gaps = 43/355 (12%)

Query: 46  NDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE 105
            + ++    + T L      +  T + +YLK E     G+ K      +        K +
Sbjct: 11  ANSMRGNEIKKTPLIHSPTFSELTKSEVYLKAEFRQKTGSFKIRGAYYKIKSLSDEEKKQ 70

Query: 106 IIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSAT 165
            +    AG H    ALASAL  + C I M           V   +  GA V+        
Sbjct: 71  GVVAASAGNHAQGVALASALEEIPCTIVMPKNA---SPAKVAATKGYGANVVLEGVNYDE 127

Query: 166 LKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPD 225
                 E  ++             T       P I+   Q +IG E    + +      D
Sbjct: 128 SSAKAKEIAKETGA----------TMIHAFDDPQIIAA-QGVIGLEILEDLPD-----VD 171

Query: 226 AVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKA 284
            V   +GGG  A G          NV +IGV+              +K G +    G + 
Sbjct: 172 QVYLPIGGGGLAAGTLIAIKEKNPNVQVIGVQSRSFPSMYE----SVKQGSITASGGAR- 226

Query: 285 PMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEG 344
                         +I+ G+     G     + +    + V + D E  +A   L     
Sbjct: 227 --------------TIADGISVKVPGQLTFSVINELIDEVVLVDDTEITKAMFLLMERMK 272

Query: 345 IIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDI--FTVHDILKARGEI 397
            +     + +LA+ +   ++    ++++ V   G  D  +    V   L A G +
Sbjct: 273 FVVEPAGAASLAYLI--SKKPAPGKKVVAVLAGGNVDMYLLGQIVDKGLAAMGRL 325


>UniRef50_D2RYT3 Threonine dehydratase n=1 Tax=Haloterrigena turkmenica DSM 5511
           RepID=D2RYT3_9EURY
          Length = 403

 Score =  195 bits (496), Expect = 2e-48,   Method: Composition-based stats.
 Identities = 66/349 (18%), Positives = 119/349 (34%), Gaps = 42/349 (12%)

Query: 44  QFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK 103
           +  + ++  + R T L +    ++ T+  ++LK E+    GA K      +        K
Sbjct: 9   EARERVRETS-RHTPLERSHTYSSMTDAEVHLKLENFQRTGAFKIRGATNRIATLSEDQK 67

Query: 104 TEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGS 163
              +    AG H    ALA+   G+  +I M       +   V   +  GAEV+      
Sbjct: 68  DAGVVTASAGNHAQGVALAATRSGVDSKIVMPEHAPISK---VKATKSYGAEVVLSGRDY 124

Query: 164 ATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRL 223
               +  +E  R+   +Y  A                V   Q  IG E      + E   
Sbjct: 125 NEAAERAHEIEREEGRTYVHAF-----------DDEYVMAGQGTIGLEILEDCPDVE--- 170

Query: 224 PDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGM 282
              V+  +GGG    G+         +V +IGV+  G                       
Sbjct: 171 --TVVVPIGGGGLISGIATAIKEQNPDVRVIGVQATGASSAAAS---------------- 212

Query: 283 KAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLH 342
              + + E   I+E  +I+ G+   SVG Q          + V+++D E   A   L   
Sbjct: 213 ---LEKGERVSIDEVDTIADGIATRSVGEQTFPYIQEYVDEVVTVSDPEIAVALVYLLER 269

Query: 343 EGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDIL 391
              +     +  LA  L    +  + E ++     G  + D+ T+ +++
Sbjct: 270 SKTLVEGAGAVPLAAVLFEKFDYDEGEVIVPALCGG--NIDLNTLTNVI 316


>UniRef50_C9M5D2 Threonine synthase n=1 Tax=Jonquetella anthropi E3_33 E1
           RepID=C9M5D2_9BACT
          Length = 380

 Score =  195 bits (496), Expect = 2e-48,   Method: Composition-based stats.
 Identities = 76/373 (20%), Positives = 125/373 (33%), Gaps = 44/373 (11%)

Query: 32  FVSAQK-DPEFQAQFNDLLKNYAGRPTALTK---CQNITAG---------TNTTLYLKRE 78
           F  A   DPE  ++ +D    Y GR   L        +  G            T++ K +
Sbjct: 30  FEQALSFDPEQLSRRHDGFWKY-GRALGLRHPEKAARLGEGQTPLLPLEWDGRTVFWKLD 88

Query: 79  DLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKD 138
            LL  G++K       A      G+ EI+ E  +G  G + A   A  G+ C +++ A  
Sbjct: 89  FLLPTGSYKDRGTAVMAASLAETGRREIV-EDSSGNAGSSLAAYCAASGITCHVFVPAST 147

Query: 139 VERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYP 198
            E +     ++   GA +  V         A            ET  Y        H + 
Sbjct: 148 SEGKC---LQIGSYGAHIHRVPGSREDTTAA-------AVAMGETHFYS------SHNWN 191

Query: 199 TIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPG 258
                  R    E   Q+     R PDAV+   G GS  IG F  F      G I   P 
Sbjct: 192 PWFALGVRTWALEAWEQMD---FRAPDAVVVPAGQGSLVIGAFRAFQELAACGAISRMPR 248

Query: 259 GHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNS 318
            + ++  E              G   P    +     E   I++           A   +
Sbjct: 249 IYAVQAAECAPL----AEAFDRGEDEPAAIEKGHTFAEG--IASAEPVRGFQVIQAVRET 302

Query: 319 TGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPD-KEQLLVVNLS 377
            GR  +V + + +    FK+L    G+     S+       ++++E      ++ +  LS
Sbjct: 303 GGR--FVRVNNGQIAAGFKSLARR-GLFVEPTSAVVAPALSELIKEGQILPNEITLTLLS 359

Query: 378 GRGDKDIFTVHDI 390
           G G K +  + ++
Sbjct: 360 GTGLKAVDHLAEL 372


>UniRef50_C6A468 Cysteine synthase n=1 Tax=Thermococcus sibiricus MM 739
           RepID=C6A468_THESM
          Length = 344

 Score =  195 bits (495), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 56/330 (16%), Positives = 104/330 (31%), Gaps = 49/330 (14%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE---IIAETGAG 113
           T + +   I       ++ K E +   G+ K          A++ GK +    IA    G
Sbjct: 20  TPIVRLSKIDKDYPFEIWAKCEFMNPTGSVKDRMAYYMIKEAEKQGKLKPGMTIAIATTG 79

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
             G+A A   +  G    I M     E          L GA++I    G +    A    
Sbjct: 80  NTGIAFAAWGSYFGYDVLIVMPE---EMSYERKLLDMLFGAKLIYTPGGESDAMGAL--- 133

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
             +++   E  +                +      G E   Q+     +     +A VG 
Sbjct: 134 --EYAKKLEKENPDKYVVLDQWDDEANFKAHYETTGREIIEQLGAENIKG---FVAGVGS 188

Query: 234 GSNAIGMFADFIN-ETNVGLIGVEPGGHG-----IETGEHGAPLKHGRVGIYFGMKAPMM 287
           G   +G+     +    +   G+EP          ++GE GA  +H   GI  G      
Sbjct: 189 GGTLVGIAKRLKDANPRIITAGMEPAECPTAEGWFKSGELGAWGRHEVEGIGDGFV---- 244

Query: 288 QTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIP 347
                                  P           D+V+++ DEA+E  + +   E +  
Sbjct: 245 -----------------------PSLVEKYKQYIDDWVTVSSDEAIEMARRIARREALGV 281

Query: 348 ALESSHALAHALKMMRE--NPDKEQLLVVN 375
            + S   +  A+K+       + ++++ + 
Sbjct: 282 GISSGANVVAAIKLAERHNFGEGDRVVTIL 311


>UniRef50_C3BFH3 Threonine dehydratase catabolic n=6 Tax=Bacillus RepID=C3BFH3_9BACI
          Length = 412

 Score =  195 bits (495), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 74/383 (19%), Positives = 125/383 (32%), Gaps = 62/383 (16%)

Query: 11  EFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTN 70
            FGG +     M +L+ +  A    +                    T L      +  ++
Sbjct: 5   RFGGEH-----MISLQDIIAAHEKMKG---------------IVHMTPLDYSSTFSELSH 44

Query: 71  TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKC 130
             +YLK E+L   G+ K      + +   +      +    AG H    A +S +LG+ C
Sbjct: 45  NEVYLKLENLQKTGSFKVRGSYNKMVSLDKGELENGVVAASAGNHAQGVAYSSNMLGIPC 104

Query: 131 RIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGT 190
            I M       +   V   +  GA V           DA   AL     +          
Sbjct: 105 TIVMPKGAPLSK---VLATKRYGAHVEL---QGDVFDDALAYALDLKEQTGAK------- 151

Query: 191 AAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFIN-ETN 249
              P      V   Q  +G E   Q  +      DAVI  VGGG    G+       + +
Sbjct: 152 FVHPFDDEA-VIAGQGTVGLEIMQQFDDI-----DAVICPVGGGGLIAGIAMAIKEQKPS 205

Query: 250 VGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSV 309
           V + GV+                        GMK    + +   +E S +++ G+     
Sbjct: 206 VKIYGVQALACP-------------------GMKQSFEEKKVITVESSPTMADGIAVKRP 246

Query: 310 GPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKE 369
           G     L      D   + + E       L     ++     + +LA    + ++ P KE
Sbjct: 247 GELTFQLVERYVDDIFCVDEMEIARTMLMLLERNKLLVEGSGASSLAAL--LYQKVPVKE 304

Query: 370 QLLVVNLSGRGDKDIFTVHDILK 392
           + +V  LSG G+ D+  +  I++
Sbjct: 305 KKVVSVLSG-GNVDVNFITRIIE 326


>UniRef50_B6YXV5 Threonine synthase n=2 Tax=Thermococcus RepID=B6YXV5_THEON
          Length = 377

 Score =  194 bits (494), Expect = 4e-48,   Method: Composition-based stats.
 Identities = 69/352 (19%), Positives = 112/352 (31%), Gaps = 35/352 (9%)

Query: 37  KDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQAL 96
           +  +F     +L  +     T L +   +       LYLK E      + K         
Sbjct: 41  RFYDFWPVEPNLELSLGEGDTPLIRS-RLGKELGVKLYLKNETANPTWSFKDRGTFLAMS 99

Query: 97  LAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEV 156
            A ++G    +     G    + A  +A  GLK +I +     + +   V      GA+V
Sbjct: 100 YAVKVGYKA-VGTVSTGNMAASVAAYAARAGLKAKILVSGSASDEKLKAVSI---YGADV 155

Query: 157 IPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQI 216
           I V      L     E   +         Y + +            E  + I  E   ++
Sbjct: 156 IRVMGDYGRLYFESLELGEEL------GIYFMNS------DNPFRVEGYKSIAFEIAEEL 203

Query: 217 LEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRV 276
                  PD V+     G    G+   F+     GLI   P    ++        +    
Sbjct: 204 ------TPDYVLIPTSSGGLFRGIAKGFLELFASGLIDKIPTLIAVQAEGCSPICRAFSE 257

Query: 277 GIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAF 336
           G     +    +T    IE          +P  G     L        V+++D+E LEA 
Sbjct: 258 GKGRIERFETPRTIAHAIENP--------YPPSGNVVLKLLRELGGKCVTVSDEEILEAQ 309

Query: 337 KTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVH 388
           K L   EG      S+  +A   K+   N  +E  +V  L+G G K I  + 
Sbjct: 310 KRLAE-EGFFVQPSSATGIAALKKL---NIPEEAKVVSILTGSGLKTISQIE 357


>UniRef50_Q2S3I1 Cystathionine beta-synthase n=30 Tax=cellular organisms
           RepID=Q2S3I1_SALRD
          Length = 505

 Score =  194 bits (494), Expect = 4e-48,   Method: Composition-based stats.
 Identities = 59/349 (16%), Positives = 109/349 (31%), Gaps = 45/349 (12%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK---TEIIAETGAG 113
           T L +   I +    T+  K E    GG+ K          A++ G+      I E  +G
Sbjct: 45  TPLVRLNEIGSDLPPTILAKVEFFNPGGSVKDRIGRALIEEAEKEGRIEPGGTIIEGTSG 104

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSG-SATLKDACNE 172
             G   A+ +   G +C         ++    V  +R +GAEV+   +        +   
Sbjct: 105 NTGAGLAITAIAKGYRCIF---TTTDKQSQEKVDVLRGLGAEVLVCPTNVEPDDPRSYYS 161

Query: 173 ALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVG 232
             R  S     + Y        +  P   +      G E   Q   +        +A  G
Sbjct: 162 VARRLSEEIPNSIY-----LNQYDNPANAKAHYETTGPELWEQTEGQI----THFVAGAG 212

Query: 233 GGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTED 291
            G    G        + ++ +IGV+P G       H              +     +   
Sbjct: 213 TGGTISGTANYLKEQDDDISVIGVDPCGSVFHKYFHEGVFDE------DEIYPYFTEGVG 266

Query: 292 GQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALES 351
             I         +D                 D+V + D  +++  + L   EG+      
Sbjct: 267 EDILPDNMDFDIVD-----------------DFVEVNDKASMQMTRRLAREEGLFIGQSC 309

Query: 352 SHALAHALKMMRENPD---KEQLLVVNLSGRGDKDIF--TVHDILKARG 395
             A+A  L+ ++ + D    + ++VV L   G + +      D ++  G
Sbjct: 310 GLAVAGTLQWVKAHRDELTPDDVVVVLLPDSGFRYLSKTYNDDWMQNHG 358


>UniRef50_P00927 Threonine dehydratase, mitochondrial n=48 Tax=cellular organisms
           RepID=THDH_YEAST
          Length = 576

 Score =  194 bits (494), Expect = 4e-48,   Method: Composition-based stats.
 Identities = 64/375 (17%), Positives = 118/375 (31%), Gaps = 41/375 (10%)

Query: 15  MYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLY 74
            ++   L+    +L+   +     P++               + +++   +++  NT + 
Sbjct: 37  QHLSPSLIKLHSELKLDELQTDNTPDYVRLVLRSSVYDVINESPISQGVGLSSRLNTNVI 96

Query: 75  LKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYM 134
           LKREDLL   + K               + + +    AG H    A A+  L +   I M
Sbjct: 97  LKREDLLPVFSFKLRGAYNMIAKLDDSQRNQGVIACSAGNHAQGVAFAAKHLKIPATIVM 156

Query: 135 GAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGP 194
                  +  NV R   +G++V+   +     K  C +   +             T   P
Sbjct: 157 PVCTPSIKYQNVSR---LGSQVVLYGNDFDEAKAECAKLAEERG----------LTNIPP 203

Query: 195 HPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFIN-ETNVGLI 253
             +P  V   Q  +  E   Q+         AV   VGGG    G+ A       ++ +I
Sbjct: 204 FDHP-YVIAGQGTVAMEILRQVR--TANKIGAVFVPVGGGGLIAGIGAYLKRVAPHIKII 260

Query: 254 GVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQH 313
           GVE      +       L+  +                       + + G     +G + 
Sbjct: 261 GVET----YDAATLHNSLQRNQRTPLP---------------VVGTFADGTSVRMIGEET 301

Query: 314 AYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMM----RENPDKE 369
             +      + V +  DE   A K +      I     + ++A   K +     E    +
Sbjct: 302 FRVAQQVVDEVVLVNTDEICAAVKDIFEDTRSIVEPSGALSVAGMKKYISTVHPEIDHTK 361

Query: 370 QLLVVNLSG-RGDKD 383
              V  LSG   + D
Sbjct: 362 NTYVPILSGANMNFD 376


>UniRef50_B3T1L2 Putative Pyridoxal-phosphate dependent enzyme n=1 Tax=uncultured
           marine microorganism HF4000_010I05 RepID=B3T1L2_9ZZZZ
          Length = 356

 Score =  194 bits (494), Expect = 4e-48,   Method: Composition-based stats.
 Identities = 69/331 (20%), Positives = 121/331 (36%), Gaps = 34/331 (10%)

Query: 57  TALTKCQNITAGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           T   + Q+         LY K E L   G+ K         +A+  G  EI+ E  +G  
Sbjct: 52  TPCVELQSTGEFLGLCGLYGKLEFLNPTGSFKDRGTAIMISVAREQGVAEIV-EDSSGNA 110

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
           G + A  +A  G++  I++ A     +   + ++++ GA+   V        DA   A+ 
Sbjct: 111 GASVAAYAARTGIRAHIFVPASAPAAK---IQQIKVYGAQTHSVEGPREATTDA---AVA 164

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
             +          G     H       E  +    E  +Q  +    LP+ ++  VG GS
Sbjct: 165 FSNEH--------GLVYASHNLSPYFIEGTKTFPYEVASQWAD---DLPEHLVIPVGNGS 213

Query: 236 NAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIE 295
             IG +  F    + G I   P  H ++       +   R G            E     
Sbjct: 214 LFIGAWKGFQELLDGGQISKMPRIHCVQAMAISPIVAAYRGG------------EWSPKA 261

Query: 296 ESYSISAGLDFPSVGPQHAYLNSTGRAD--YVSITDDEALEAFKTLCLHEGIIPALESSH 353
            + +++ G+   S   +   L   G  D   V++ ++E LE    L   EGI     S+ 
Sbjct: 262 GARTVAGGIASASPPRKPQMLAVLGATDGVAVAVEEEEILEWQLQLARREGIYAEPTSAA 321

Query: 354 ALAHALKMMREN-PDKEQLLVVNLSGRGDKD 383
           A A   +++        + ++V ++G G KD
Sbjct: 322 AFAGLARLVEMGTIRSSETVLVPITGSGLKD 352


>UniRef50_A1A3R8 Catabolic threonine dehydratase n=8 Tax=Bifidobacterium
           RepID=A1A3R8_BIFAA
          Length = 421

 Score =  194 bits (493), Expect = 5e-48,   Method: Composition-based stats.
 Identities = 61/373 (16%), Positives = 113/373 (30%), Gaps = 43/373 (11%)

Query: 26  RQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGA 85
            +  E   + ++D   + +          R T +     ++  T   + LK E+L   G+
Sbjct: 1   MEQNEVLKALRRDHAAELKLAAERLKGTARHTEIIPSPVLSEMTGHEILLKPENLQVTGS 60

Query: 86  HKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPN 145
            K      +            I    AG H    A A+   G K  I M           
Sbjct: 61  FKIRGAYNKIASLTDEQLAHGIVTASAGNHAQGVAYAARERGAKATICMPQITP---PLK 117

Query: 146 VFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQ 205
           V   +  GA+V+            C E   + +   +      G    P      V   Q
Sbjct: 118 VDATKAYGADVVL-----------CGEVFDESAAHAQELSDNEGMIYVPPFDDYEVLCGQ 166

Query: 206 RMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETG 265
             IG E    +      +       +G           F     V +IG  P G      
Sbjct: 167 GTIGLEILEDVPNVTDVVVPLGGGGLGA--GVALAIKTFK--PEVRVIGAIPEGSPA--- 219

Query: 266 EHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYV 325
                L  GRV     ++               + + G+     G     L +    D V
Sbjct: 220 -WKNSLAAGRVVAADQVR---------------TSAEGVAVKRPGDLTFALLNEFLDDLV 263

Query: 326 SITDDEALEAFKTLCLHEGIIPALESSHALAHALKM---MRENPDKEQ--LLVVNLSGRG 380
           ++T+ +  E    +     ++     + +LA    +    R+  + +   ++V  LSG G
Sbjct: 264 TVTERDINEMILLMLEKHKLVVEAAGAVSLAALEHLNLRSRKFAEAKGPHVVVPILSG-G 322

Query: 381 DKDIFTVHDILKA 393
           ++D  ++  +++ 
Sbjct: 323 NEDTVSISAVIQK 335


>UniRef50_D1C1V4 Threonine synthase n=3 Tax=Bacteria RepID=D1C1V4_SPHTD
          Length = 415

 Score =  194 bits (493), Expect = 5e-48,   Method: Composition-based stats.
 Identities = 70/329 (21%), Positives = 121/329 (36%), Gaps = 29/329 (8%)

Query: 57  TALTKCQNITAGTN-TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           T L     +        L +K +     G+ K   +      AK +G +  +A   AG  
Sbjct: 81  TPLLPASRLGKALGYNRLLVKDDGQNPTGSFKARGLCAAVSRAKELGASA-VAIPSAGNA 139

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
             A +  +A  GL   ++M A   E   P     R  GA V  V      L + C   +R
Sbjct: 140 AAAMSAYAARAGLDAYVFMPADTPE---PMKAECRAYGARVFLVIG----LINDCGRVVR 192

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
             + +     + + T   P+       E ++ +G E   Q+     RLPDA++   GGG+
Sbjct: 193 AGAEA--RGWFDVSTLKEPYR-----AEGKKTMGLELAEQL---GWRLPDAIVYPTGGGT 242

Query: 236 NAIGMFADFINETNVGLIGVE-PGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQI 294
             +GM+  F     +GLIG E P    +++      ++    G           T    I
Sbjct: 243 GIVGMWKAFDELEQLGLIGSERPRMIVVQSEGCAPIVRAFEQGERHAQLWEGAATVAPGI 302

Query: 295 EESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHA 354
               +I   L                    ++++D+E LE  +    HEG+  + E+   
Sbjct: 303 RVPVAIGDYL--------ILDAVRQSGGTAITVSDEELLEGMRLAATHEGLFVSPEAGAV 354

Query: 355 LAHALKMMREN-PDKEQLLVVNLSGRGDK 382
           +A A  +       ++  +V+  +G G K
Sbjct: 355 VAAARLLRERGVLGQDDEVVLFATGAGLK 383


>UniRef50_Q9K7E3 Threonine synthase n=82 Tax=cellular organisms RepID=THRC_BACHD
          Length = 354

 Score =  194 bits (492), Expect = 6e-48,   Method: Composition-based stats.
 Identities = 72/335 (21%), Positives = 112/335 (33%), Gaps = 45/335 (13%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T L   +N++       Y+K E     G+ K   ++     AK  G   II     G   
Sbjct: 31  TPLIPLENLSKEWGVKAYVKYEGANPTGSFKDRGMVMAVAKAKEEGSRTIICA-STGNTS 89

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD 176
            A+A   A  GL+C + +    +         M   GAEV+ +           + AL  
Sbjct: 90  AAAAAYGARAGLRCIVVIPEGKIALGKLAQAVM--YGAEVLEIKGN-------FDHALDI 140

Query: 177 WSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSN 236
                E     L  +  P+       E Q+    E    +    G+ PD +   VG   N
Sbjct: 141 VRSISEKEPITLVNSVNPYR-----IEGQKTSAFEICDAL----GQAPDVLAIPVGNAGN 191

Query: 237 AIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEE 296
               +  F         G  P   G E     A ++                  +  IEE
Sbjct: 192 ITAYWKGFKEYHEKKGTG-LPQMRGFEAEGAAAIVR------------------NQVIEE 232

Query: 297 SYSISAGLDFPSVG----PQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESS 352
             +I+  +   +         A   S G+ D   +TD+E L A++ L   EG+     S 
Sbjct: 233 PETIATAIRIGNPASWTYAVEAAAESNGKID--EVTDEEILAAYQLLAQKEGVFAEPASC 290

Query: 353 HALAHALKMMRENP-DKEQLLVVNLSGRGDKDIFT 386
            ++A   K +      K   +V  L+G G KD  T
Sbjct: 291 ASIAGLRKQIASGEIKKGSTVVCVLTGNGLKDPNT 325


>UniRef50_C2KWC0 Threonine ammonia-lyase n=1 Tax=Oribacterium sinus F0268
           RepID=C2KWC0_9FIRM
          Length = 410

 Score =  194 bits (492), Expect = 7e-48,   Method: Composition-based stats.
 Identities = 62/344 (18%), Positives = 114/344 (33%), Gaps = 44/344 (12%)

Query: 51  NYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAET 110
                 T L     I   T+  LYLK E+L + G+ K      +        + + +   
Sbjct: 28  KPVIHKTDLVHATRI--QTDCDLYLKTENLQNTGSFKIRGAYFKISTLSEEERKKGVVAC 85

Query: 111 GAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDAC 170
            AG H    ALA+   G K  I++ A     +   V   R  GA V  +        +A 
Sbjct: 86  SAGNHAQGVALAAQASGTKSTIFLPAIAPISK---VEATRSYGASVKMIDGVYDDAYEAA 142

Query: 171 NEALRDWSGSYETAHYMLGTAAGPHPYPTI-VREFQRMIGEETKAQILEREGRLPDAVIA 229
            +   +              +   HP+  + V   Q  IG E   Q+ + +  +      
Sbjct: 143 VKFQEE------------HGSVFIHPFNDVDVMAGQGTIGMEILDQLEDADAVVVPVGGG 190

Query: 230 CVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQT 289
            +     +   F          + GV+  G                          +   
Sbjct: 191 GL----ISGISFVIKKLNPKCKVYGVQAQGAASMVQA-------------------VKDH 227

Query: 290 EDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPAL 349
               +EE ++ + G+   S G     +      + V++TDDE   A  TL   + I+   
Sbjct: 228 HLESLEEVHTFADGIAVKSPGSLSYAMVEKYVDELVTVTDDETAAAILTLMERQKIVSEG 287

Query: 350 ESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
             + ++A    +  + P K + +V  +SG G+ D+  +  ++  
Sbjct: 288 AGAVSVAAV--LFNKIPVKGKKVVAVISG-GNIDVNILARVINR 328


>UniRef50_B6JZ56 Cysteine synthase n=1 Tax=Schizosaccharomyces japonicus yFS275
           RepID=B6JZ56_SCHJY
          Length = 411

 Score =  194 bits (492), Expect = 7e-48,   Method: Composition-based stats.
 Identities = 58/354 (16%), Positives = 109/354 (30%), Gaps = 28/354 (7%)

Query: 51  NYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE----- 105
                 T L + ++++  T   +  K E L  G + K    L     A+  G        
Sbjct: 53  EGLIGNTKLVRIKSLSEATGCDILAKAEHLNPGNSAKDRVALFILKDAEERGLLRPKQGD 112

Query: 106 IIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSAT 165
           ++ E  +G  G++ A+    LG + RIYM     + +S  +     +GA+V  V      
Sbjct: 113 VVFEGTSGSTGISFAMLGRSLGYETRIYMPNDQAQEKSDMLSM---LGADVHRVPPAPIM 169

Query: 166 LKDACNEALRDWSGSYETAHYML--GTAAGPHPYPTIVREFQRMIGEETKAQILEREGRL 223
            +       RD +            G  A         R      G E   Q        
Sbjct: 170 DRKNFVNIARDKAKELTDDVNTPNKGYFANQFENLANWRAHYETTGPEIWRQCA----GR 225

Query: 224 PDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGM 282
            DA +   G G    G          N+ +   +P G G+        +   R       
Sbjct: 226 VDAFVTGSGTGGTIAGTSRFLKEKNRNILVCLSDPPGSGLYNKIVNGVMFDIREKEGTRR 285

Query: 283 KAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLH 342
           +  +            +I  G+    +    + +          ITD +A++  + L  +
Sbjct: 286 RKQV-----------DTIVEGIGLNRMTRNFS-IAEPLIDWAYRITDAQAVQMSRWLVHN 333

Query: 343 EGIIPALESSHALAHALKMMRENPDKEQLL-VVNLSGRGDKDIFTVHDILKARG 395
           +G+     S+     A+K+ ++     +++ +    G            L   G
Sbjct: 334 DGLFVGSSSALNCVAAVKIAKKLGPGHRIVTIFCDPGHRHSSKLYNDAFLDKEG 387


>UniRef50_D1CDZ3 Pyridoxal-5'-phosphate-dependent protein beta subunit n=1
           Tax=Thermobaculum terrenum ATCC BAA-798
           RepID=D1CDZ3_THET1
          Length = 353

 Score =  193 bits (491), Expect = 8e-48,   Method: Composition-based stats.
 Identities = 68/351 (19%), Positives = 112/351 (31%), Gaps = 45/351 (12%)

Query: 44  QFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK 103
           +  D +  Y  R T L +   ++      +YLK E     GA K      + L      K
Sbjct: 27  EARDRISPYIER-TPLKESHTLSNRLGAKVYLKLEMFQTTGAFKIRGAFNKMLSLSPEEK 85

Query: 104 TEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGS 163
              +     G H  A A A++ LG+K  ++M     E     +      GA+V+      
Sbjct: 86  NRGVVAVSGGNHAQAVAYAASKLGIKATVFMARNTPEN---YIEATEHYGAQVVLTS--- 139

Query: 164 ATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTI-VREFQRMIGEETKAQILEREGR 222
                   EA +  +                HPY    V   Q  IG E    + +    
Sbjct: 140 -----DIAEAFKLAAERQAYG------EVMIHPYADNQVMAGQGTIGLEILEDLPQVTD- 187

Query: 223 LPDAVIACVGGGSNAIGMFADFI-NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFG 281
               VI  +GGG    G+       + +V + GVE  G           L+ G       
Sbjct: 188 ----VIISIGGGGLISGVATAIKSQKPHVRIWGVETAG----ADSMSQALRAGHPIELPA 239

Query: 282 MKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCL 341
           +                SI+  L  PSV      +          ++D EA +A + L  
Sbjct: 240 IT---------------SIAKTLGAPSVSENTLAITRKLVESVTVVSDKEAFQALEFLLE 284

Query: 342 HEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRG-DKDIFTVHDIL 391
              ++    +S  LA A ++      +  L+++   G     D+     + 
Sbjct: 285 RAKVLTEPAASCTLAAAERLRSAFTPQSTLVLLLCGGNVSLADLCHYRQMF 335


>UniRef50_D1TEY8 Pyridoxal-5'-phosphate-dependent protein beta subunit n=1
           Tax=Burkholderia sp. CCGE1002 RepID=D1TEY8_9BURK
          Length = 329

 Score =  193 bits (491), Expect = 8e-48,   Method: Composition-based stats.
 Identities = 70/339 (20%), Positives = 111/339 (32%), Gaps = 41/339 (12%)

Query: 56  PTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
            T L +   +       +YLK E L   G+ K    L + L   R    + I  + +G H
Sbjct: 24  HTPLLRESKMDKSLGCHVYLKPEMLQVTGSFKIRGALNKILSLTRKELDKGIITSSSGNH 83

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
           G A A A  LLG+   + +       +  N    + MGA+VI           +  E  +
Sbjct: 84  GQACAYAGQLLGIHTTVIVPNDAPSLKVEN---AKSMGADVIL-------WDRSYEERWK 133

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
                 E   Y +            V   Q  IG E    + +      D V+  +GGG 
Sbjct: 134 KVHADVEEHGYTIVHNYEDFD----VMAGQGTIGLEIIEDLPD-----VDTVLVPIGGGG 184

Query: 236 NAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQI 294
              G+          + +IGV+            A    G       M+           
Sbjct: 185 LISGISIAIKESNARIKVIGVQAAACCPYYMSRQA----GERTKAASMR----------- 229

Query: 295 EESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHA 354
               +I+ GL     G     +      D V ++++   EA +T+     ++    S   
Sbjct: 230 ----TIADGLACNFPGNHPYPIIEKYVDDIVIVSEEAIEEAVRTVANDAKLVAEPSSCVG 285

Query: 355 LAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
           +A  L         E++ VV  SG  D D   +  ILK 
Sbjct: 286 IAALLSGAVRTGADEKVCVVLTSGNWDID--RIGSILKK 322


>UniRef50_UPI00006A66AE PREDICTED: similar to GH19036 n=1 Tax=Ciona intestinalis
           RepID=UPI00006A66AE
          Length = 444

 Score =  193 bits (491), Expect = 9e-48,   Method: Composition-based stats.
 Identities = 58/332 (17%), Positives = 107/332 (32%), Gaps = 36/332 (10%)

Query: 63  QNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALA 122
             ++      ++ K+E +   G+ K    L   L      +   +  T AG H  A A  
Sbjct: 61  SRMSHNLGIDIFFKKEFMQFTGSFKDRGALYSLLKLSDEQRRGGVVTTSAGNHAQALAYQ 120

Query: 123 SALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYE 182
              L +   + M  +    +   V   + + A VI          +A + A+        
Sbjct: 121 GRKLNIPVTVVMPMQAPLVK---VNSCKDLQATVIL---HGQRFDEAKSYAMAYGKKH-- 172

Query: 183 TAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFA 242
              Y+ G     + +P I    Q  IG E    + +      D ++  +GGG    G+ A
Sbjct: 173 NLLYING-----YDHPDI-LAGQGTIGLEILEDVPD-----VDCIVVPIGGGGLVAGIAA 221

Query: 243 DFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSIS 301
              +    + +IGVE                     +  G   P   ++ G      SI+
Sbjct: 222 AAKHIRPEIKIIGVESQKCP-----------SWTSAVNNGKPLPCPISKQGA---KDSIT 267

Query: 302 AGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKM 361
            GL    VG              V++++D    A   L   E  +     +   A  +  
Sbjct: 268 DGLSVIEVGVNSYATAHPLMDKMVTVSEDYVCTAILQLMEFEKSVVEGAGAAGFAAIIAG 327

Query: 362 MRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
           +       +++ V   G  + DI T+  ++  
Sbjct: 328 LLPELHGLKVVTVLCGG--NIDITTLGRVIDR 357


>UniRef50_B9Z5C8 Cysteine synthase n=1 Tax=Lutiella nitroferrum 2002
           RepID=B9Z5C8_9NEIS
          Length = 453

 Score =  192 bits (489), Expect = 1e-47,   Method: Composition-based stats.
 Identities = 62/349 (17%), Positives = 108/349 (30%), Gaps = 43/349 (12%)

Query: 53  AGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG---KTEIIAE 109
           A   T L +   +T   +  +Y K E +  GG+ K          A+R G       I E
Sbjct: 9   AIGHTPLVRLNRLTRQFDCAVYAKLEFMNPGGSVKDRIGQFMVGEAERRGEIAPGGTIVE 68

Query: 110 TGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSG-SATLKD 168
             +G  G+  A+ +A  G +  ++  A   ++    +  +R MGAEVI   +        
Sbjct: 69  CTSGNTGMGLAMFAAARGYR-TVFTIAD--KQSREKIDMLRAMGAEVIVCPTDLPPDHPR 125

Query: 169 ACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVI 228
              E  R  +     A          +  P   R      G E                +
Sbjct: 126 QYIEVARRLAVEIPGAFLC-----NQYHNPDNTRAHYVSTGPEIWHD----TEGKITHFV 176

Query: 229 ACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMM 287
            C+G      G+          V +IGV+P G  +    H         G         +
Sbjct: 177 CCMGTCGTISGIGRYLKEQNPAVQVIGVDPEGSILYDLFHS--------GREVEPHVYKL 228

Query: 288 QTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIP 347
           +                           L+ +   D + + D ++    + L   EGI  
Sbjct: 229 EGIGEDFVPG-----------------ALDWSVIDDVIQVGDKDSFLMTRHLAHSEGIFA 271

Query: 348 ALESSHALAHALKMMRENPDKE-QLLVVNLSGRGDKDIFTVHDILKARG 395
              S  A+  AL++       +  ++++   GR         D ++A G
Sbjct: 272 GGSSGAAILAALQVAERLGPGDLMVVLLPDGGRQYLGKIYNDDWMRANG 320


>UniRef50_Q07RL7 L-threonine ammonia-lyase n=40 Tax=Bacteria RepID=Q07RL7_RHOP5
          Length = 345

 Score =  192 bits (487), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 68/352 (19%), Positives = 119/352 (33%), Gaps = 38/352 (10%)

Query: 42  QAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRM 101
                 +LK YA R T L     + A T   ++LK E L   G+ K      +       
Sbjct: 15  IEAAAQVLKPYAVR-TPLLSSPALDALTGARVFLKPEMLQRTGSFKFRGAFNKLSSIPAE 73

Query: 102 GKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS 161
            +   +    +G H    A A+ +LG++  I M A     +     R +  GAEV+    
Sbjct: 74  ARAGGVVAFSSGNHAQGVAAAAQILGMRATIVMPADAPASK---RERTKSYGAEVVL--- 127

Query: 162 GSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREG 221
               L++      R  +               P+  P  V   Q  +G E    +  + G
Sbjct: 128 -YDRLREDREAIARRIAEQTGAT------LVPPYDDPK-VIAGQGTVGREIVQDLAAQ-G 178

Query: 222 RLPDAVIACVGGGSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYF 280
             PD VIA   GG    G+     +      ++  EP        +H   L+ G+   + 
Sbjct: 179 LSPDLVIAPASGGGLLAGIAVAVRSHCPQATILCAEPEAF----DDHARSLRAGQREPHR 234

Query: 281 GMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLC 340
                          +  +I   L     G     +N    A  ++++D E   A   + 
Sbjct: 235 --------------ADGPTICDALMAAIPGQLTFSINHRLLARGLTVSDAEVAAAVGFVF 280

Query: 341 LHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILK 392
               ++       A+A A  +      + +++ V LSG G+ D      +++
Sbjct: 281 RELKLVVEPG--GAVALAALLAGRIQGRGEVIAVVLSG-GNVDPDMFARLIE 329


>UniRef50_A3DLX2 L-threonine ammonia-lyase n=2 Tax=Thermoprotei RepID=A3DLX2_STAMF
          Length = 419

 Score =  192 bits (487), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 63/372 (16%), Positives = 118/372 (31%), Gaps = 56/372 (15%)

Query: 26  RQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGA 85
             +E  +  + +  E   +F           T L     I+       YLK E++   G+
Sbjct: 11  SDIENIYKLSLEASEVIQEF--------IHKTPLVYNYTISNIVGCDTYLKLENMQKTGS 62

Query: 86  HKTNQVLGQALLAKRM-----GKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVE 140
            K      +  +  +       K   +    +G H    A A+ + G+   I M      
Sbjct: 63  FKVRGATFKIYMLIKEYESRGEKLPGVVAASSGNHAQGVAYAAKVFGIPAIIVMPKTASS 122

Query: 141 RQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTI 200
            +   +   +  GAEV+          +  +EA            Y+      P+  P  
Sbjct: 123 TK---INATKSYGAEVVL-------HGEIYDEAYEKAIEISREKGYV---FIHPYDDP-Y 168

Query: 201 VREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINE-TNVGLIGVEPGG 259
           +   Q  IG E   ++     + P  V+  +GGG    G+         N  +IGV+P  
Sbjct: 169 IIAGQATIGHEIIDEL-----KKPVVVLVPIGGGGLISGIAVAVKKRSPNTKIIGVQPA- 222

Query: 260 HGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNST 319
                  + + + H   G   G +               SI+ G+     G   + +   
Sbjct: 223 -------NASAMLHLIQGRIEGYR------------PKPSIADGVMVKKPGDLTSRIVRE 263

Query: 320 GRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGR 379
              D V + +++   A   L     I+     +  +A    +          +V  +SG 
Sbjct: 264 LVDDIVVVDEEDISYAINFLLERAKIVAEGAGALPIAAL--LSHRYSPIRGPVVAVISG- 320

Query: 380 GDKDIFTVHDIL 391
           G+ D   +  I+
Sbjct: 321 GNIDPALLSRII 332


>UniRef50_C9RSS0 Threonine synthase n=13 Tax=Bacteria RepID=C9RSS0_GEOSY
          Length = 405

 Score =  191 bits (486), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 69/367 (18%), Positives = 128/367 (34%), Gaps = 34/367 (9%)

Query: 28  LEEAFVSAQKDPEFQAQFN-DLLKNYAGRPTALTKCQNITAGTNTT-LYLKREDLLHGGA 85
           L E   +  +  E     + + + +     T L     +        LY+K E ++  G 
Sbjct: 51  LREREANLWRYHELLPVKHPEHIVSLGEGMTPLVPMMRLGRKIGIEALYMKDEGVIPTGT 110

Query: 86  HKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPN 145
            K          AK +G  ++ A    G  G A +L +A  G++  + M     E     
Sbjct: 111 FKARGAAVGVSKAKELGVKQL-AMPTNGNAGAAWSLYAARAGIQATVVMPVDAPE---LT 166

Query: 146 VFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQ 205
                + GAE+  V+   +       +A+R++        Y   T   P+       E +
Sbjct: 167 RKECAIAGAELYLVNGLISDAGQIVAKAIREY------GWYDASTLKEPYR-----IEGK 215

Query: 206 RMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLI-GVEPGGHGIET 264
           + +G E   Q      +LPD ++   GGG   IG++        +G + G  P    ++ 
Sbjct: 216 KTMGLEIAEQFS---WQLPDVILYPTGGGVGLIGIYKAIKELQALGWVDGRMPRLVAVQA 272

Query: 265 GEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRAD- 323
                 +K  +         P           +++++ G++ P        L +    D 
Sbjct: 273 EHCAPIVKAWKEKKRESKFWP----------NAHTVAFGINVPKALGDFLVLEAVYETDG 322

Query: 324 -YVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMREN-PDKEQLLVVNLSGRGD 381
             +++ D+  L   +T    EG     E + A A A  +         + +VV  +G G 
Sbjct: 323 CAIAVNDEAILAEQRTAAELEGAFICPEGAAAFAAARTLRESGWIRDGETVVVLNTGTGL 382

Query: 382 KDIFTVH 388
           K   TV 
Sbjct: 383 KYADTVD 389


>UniRef50_Q6C6D8 YALI0E10307p n=1 Tax=Yarrowia lipolytica RepID=Q6C6D8_YARLI
          Length = 329

 Score =  191 bits (486), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 76/355 (21%), Positives = 121/355 (34%), Gaps = 44/355 (12%)

Query: 51  NYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE----- 105
                 T L K    +      +YLK E+L   G+ K+  +      A            
Sbjct: 2   RPGYIETPLLKNDIFSHQVGCNVYLKMENLQPSGSFKSRGMTQVISDALDSDPQASLDTL 61

Query: 106 IIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSAT 165
            +  +  G  G+A+A+ S L G+ C + +       +   V ++R  GAEVI        
Sbjct: 62  HVCSSSGGNAGLAAAVTSRLNGVACTVVVPEST---KPRMVEKLRAAGAEVIV---HGKH 115

Query: 166 LKDACNEALRDWSGSYETAHYMLGTAAGPHPYPT-IVREFQRMIGEETKAQILEREGRLP 224
             +A +   ++     E       T    HP+    V +    + +E   Q     G  P
Sbjct: 116 WSEANDFLQKEEMPRLEKT---GKTPIYCHPFDAPAVWKGNSTLIDEIIKQ-----GITP 167

Query: 225 DAVIACVGGGSNAIGMFADFINET-NVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMK 283
           DAV+  VGGG    G+         N  +I VE  G    +      L+ G      G+ 
Sbjct: 168 DAVVCSVGGGGLFNGVVEGLKRHKLNCPVIVVETNGADALS----RSLQKGEQVTLPGIT 223

Query: 284 APMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHE 343
                          SI+  L    V  +      T       ++DD+A+ A       +
Sbjct: 224 ---------------SIATSLGAVRVADKTFENAQTYPTVSAVVSDDDAVSALVEYAETK 268

Query: 344 GIIPALESSHALAH--ALKMMRENPDKEQLLVVNLSG--RGDKDIFTVHDILKAR 394
            II       +LA   ALK + +      ++VV   G   G  DI      L+A+
Sbjct: 269 QIIVEPACGASLAVLPALKDLVDLKPDSNVVVVLCGGSATGISDIAQFKKDLEAK 323


>UniRef50_O34476 Probable cysteine synthase n=7 Tax=Bacteria RepID=CYSM_BACSU
          Length = 311

 Score =  191 bits (486), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 61/334 (18%), Positives = 115/334 (34%), Gaps = 47/334 (14%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG---KTEIIAETGAG 113
           T L +   +       +YLK E     G+ K        + A++ G      +I E  +G
Sbjct: 15  TPLVRLNRLQPENAAQVYLKLEFFNPSGSVKDRAAYQMIIEAEQNGLLKPGSVIIEPTSG 74

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
             G+  A+ +A  G K  + M           +  ++  GAEV+    G   +  +  +A
Sbjct: 75  NTGIGLAMNAAARGYKAILVMPDTMT---KERINLLKAYGAEVVLTP-GEERMPGSIKKA 130

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
            ++ +     ++  +                ++    E    I E  G+   A +A  G 
Sbjct: 131 -KELAEQIPNSYIPM-----QFDNTANPDAHRKTTAPEIARAI-EEIGKPLGAFVASSGT 183

Query: 234 GSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDG 292
           G    G          ++ +  VEP G  + +G  G P  H  VG   G   P+      
Sbjct: 184 GGTITGTGEALKELFPDITVHVVEPAGSPVLSG--GKPGAHKLVGTSPGFIPPI------ 235

Query: 293 QIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESS 352
                                  LN     + + I+D++A    + L   EGI+    S 
Sbjct: 236 -----------------------LNEDVYDEIIKISDEDAYTTTRRLAAEEGILVGPSSG 272

Query: 353 HALAHALKMMRENPDKEQLLVVNLSGRGDKDIFT 386
            A   A++  +     ++++V   +  G++ + T
Sbjct: 273 AACFAAIETAKRLSP-DKVVVCMTADTGERYLST 305


>UniRef50_A3DLF6 Cysteine synthase n=2 Tax=Desulfurococcaceae RepID=A3DLF6_STAMF
          Length = 338

 Score =  191 bits (486), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 68/353 (19%), Positives = 119/353 (33%), Gaps = 54/353 (15%)

Query: 57  TALTKCQNITAGTNT--TLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE---IIAETG 111
           T + + Q I    N    ++ K E +   G+ K          A   G+ +    I    
Sbjct: 16  TPIIRLQRIEKDQNVDFEIWAKAEFMNPTGSVKDRMAYYMIKKAMDKGELKPGMTIVVPT 75

Query: 112 AGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACN 171
            G  G++ +   +  GLK  I +     E  +     MRL GA+ +    G +    A  
Sbjct: 76  TGNTGISFSALGSYFGLKVLIVIPE---EMSAERFMLMRLFGADFLFTPGGESDAGTALE 132

Query: 172 EALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACV 231
            A +    + +  ++              V+      G+E   QI       PDA +A V
Sbjct: 133 TAKKLAEENPDKYYF-----FDQWSDEANVQAHYETTGKEILDQI-----GCPDAFVAQV 182

Query: 232 GGGSNAIGMFADFINE-TNVGLIGVEPGGHGIE-----TGEHGAPLKHGRVGIYFGMKAP 285
           G G   +G+      E  NV + G EP    +      TG+ G   +H   G+  G    
Sbjct: 183 GTGGTLMGVAKRLKEECKNVIVAGAEPAECPVAAYWFKTGKEGPWGRHEIEGVGDGFVPD 242

Query: 286 MMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGI 345
           +++                                  D+V+ T +EA+   + +   E +
Sbjct: 243 IVK---------------------------RYKHLLDDFVTSTSEEAIMMARKIARLEAL 275

Query: 346 IPALESSHALAHALKMMR-ENPDKEQLLVVNLSGRGDKDIFTVHDILKARGEI 397
              + S   +  A+K+ R     K + +V  L     +   T   + K + EI
Sbjct: 276 PVGISSGANVVSAIKLGRSHGLGKGKKVVTILPDYAARYFST--RLFKKKREI 326


>UniRef50_Q9Y9K2 Threonine synthase n=1 Tax=Aeropyrum pernix RepID=Q9Y9K2_AERPE
          Length = 393

 Score =  191 bits (485), Expect = 4e-47,   Method: Composition-based stats.
 Identities = 57/335 (17%), Positives = 113/335 (33%), Gaps = 33/335 (9%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T L K +N++      +Y K E L   G+ K   +     +A       ++     G   
Sbjct: 59  TPLVKLENLSRAMGVEVYGKLEFLNPTGSFKDRGMTVGVSIASSFSY-RLVVAASTGNTA 117

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD 176
            + A  +   GL   I +    +      + ++  +GA V+ V        DA       
Sbjct: 118 ASMAAYARRAGLNPVILIPKGGIAS--GKLSQIAALGAWVLEVEGSFDDALDA------- 168

Query: 177 WSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSN 236
              + E        +  P+       E Q+ I  E    +   +  +       VG   N
Sbjct: 169 ARAAAEKGLAYSLNSINPYR-----LEGQKTIAFEILEDVDRVDHVV-----VPVGNAGN 218

Query: 237 AIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEE 296
              ++  F     +GL  + P   G++        +     +              ++  
Sbjct: 219 ISAIWKGFKEAGLLGLPSMRPRMVGVQAEGASPLYRAWVEKM----------DSVERVRN 268

Query: 297 SYSISAGLD--FPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHA 354
             +I++ +    P    +            +S++D E L+A  TL  +EG++    S+ +
Sbjct: 269 PSTIASAIRIGNPVNAAKALAAVRESDGLIISVSDAEILKAAATLAENEGMLVEPASAAS 328

Query: 355 LAHALKMMRENPDKEQ-LLVVNLSGRGDKDIFTVH 388
           LA  +K+  +        +V+ L+G G KD   + 
Sbjct: 329 LAGLIKLRNQGIIASGSSVVLILTGHGLKDPRALE 363


>UniRef50_C1EEG6 Predicted protein n=1 Tax=Micromonas sp. RCC299 RepID=C1EEG6_9CHLO
          Length = 373

 Score =  191 bits (485), Expect = 4e-47,   Method: Composition-based stats.
 Identities = 61/336 (18%), Positives = 108/336 (32%), Gaps = 46/336 (13%)

Query: 67  AGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALL 126
            G    L+ K E    GGA K    +   L   +    + +    +G H  A ALA+   
Sbjct: 71  EGATVELFFKCETFQKGGAFKFRGAMNSILQLSKADLQKGVVTHSSGNHAGALALAAKTK 130

Query: 127 GLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHY 186
           G+   I +     + +      +   G E+    +           A    +   +    
Sbjct: 131 GIPSYIVVPEGAPQCKL---DAIETYGGEITKCEATVP--------AREAAAARIQET-- 177

Query: 187 MLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFIN 246
             G    P      V   Q  IG E   Q+ +      D VI  + GG    G+      
Sbjct: 178 -TGATLIPPYNYGPVICGQGTIGLEFMEQVPDL-----DVVIVPISGGGMISGIATAVKG 231

Query: 247 -ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLD 305
            + +  +I  EP G G    +     K                     +    +I+ GL 
Sbjct: 232 IKKDCVVIAAEPVGAGAYAADTFESKKRKE--------------LVDDLPVPDTIADGLK 277

Query: 306 FPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHAL-----K 360
              +G     +        +++T+DE + A K +     ++     +  LA A+     +
Sbjct: 278 AK-MGSLTWPVVRDKVDAVITVTEDEIVAAMKIIYERLKLVVEPSGAVGLAAAMSTQFKE 336

Query: 361 MMRENPD-----KEQLLVVNLSGRGDKDIFTVHDIL 391
             R+NP      K + + V L G G+ D+  +  + 
Sbjct: 337 FNRKNPPWGKISKHKKVGVVLCG-GNVDLALLAKLF 371


>UniRef50_A9B771 Cystathionine beta-synthase n=12 Tax=Bacteria RepID=A9B771_HERA2
          Length = 463

 Score =  191 bits (485), Expect = 4e-47,   Method: Composition-based stats.
 Identities = 64/351 (18%), Positives = 117/351 (33%), Gaps = 45/351 (12%)

Query: 53  AGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK---TEIIAE 109
           A   T L +   +  G    +  K E +  GG+ K    +     A+R G+      I E
Sbjct: 19  AIGNTPLVRLNRVNRGVRAQVLAKVEYMNPGGSVKDRIGIAMIEDAERSGRLKPGGTIVE 78

Query: 110 TGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSG-SATLKD 168
             +G  G   A+A+A+ G K    M  K  + +   +  +R +GA+V+   +        
Sbjct: 79  PTSGNTGAGLAIAAAIRGYKTIFVMPDKMSDEK---IRYLRALGAKVVITPTAVEPDDPR 135

Query: 169 ACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVI 228
           +     +  +     A       AG +          R  G E   Q         DA I
Sbjct: 136 SYYSVSKRLAEETPNAI-----LAGQYWNQANPEAHYRTTGPEIWRQ----TAGKIDAFI 186

Query: 229 ACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMM 287
           A +G G    G          N+ ++G++P G       +    + G++G  FG     +
Sbjct: 187 AGMGTGGTISGTAKFLKEQNPNIQVVGIDPVGS-----LYTEYFRTGQLGPAFG---YKV 238

Query: 288 QTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIP 347
           +        +                         D V + D E+    + +   EG+  
Sbjct: 239 EGVGEDFLPTTMHF-----------------QYVDDVVQVGDKESFVMTRRMVREEGLFV 281

Query: 348 ALESSHALAHALKMMRE---NPDKEQLLVVNLSGRGDKDIFTVHDILKARG 395
                 A+A A++ +R    +  K  ++++  SG          D ++  G
Sbjct: 282 GGSCGMAVAGAMRWLRAQNWDESKTAVILLPDSGVRYISKIFSDDWMRENG 332


>UniRef50_P74193 Threonine synthase n=364 Tax=cellular organisms RepID=THRC_SYNY3
          Length = 382

 Score =  190 bits (484), Expect = 6e-47,   Method: Composition-based stats.
 Identities = 65/331 (19%), Positives = 110/331 (33%), Gaps = 38/331 (11%)

Query: 57  TALTKCQNITAGTN--TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQ 114
           T L     I         +++K + L   G+ K   +      AK  G   +I     G 
Sbjct: 61  TPLIPAPAIAKRIGKDVRVFVKYDGLNPTGSFKDRGMTMAISKAKEAGAKAVICA-STGN 119

Query: 115 HGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEAL 174
              A+A  +   GL+  + +    V         +   GAEVI +        D     +
Sbjct: 120 TSAAAAAYARRAGLRAFVIIPDGYVALGKLGQALI--YGAEVIAIDGNF----DDALTTV 173

Query: 175 RDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGG 234
           R  S  Y      L  +  P+       E Q+    E      +  G+ PD +   VG  
Sbjct: 174 RQLSEHYPVT---LVNSVNPYR-----LEGQKTAAFEIV----DVLGQAPDWLCIPVGNA 221

Query: 235 SNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQI 294
            N    +  F     +G     P   G +                     P +Q +    
Sbjct: 222 GNITAYWMGFCQYKELGKGDRLPRMMGFQAAGSA----------------PFIQGQPISH 265

Query: 295 EESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHA 354
            E+ + +  +  P+   +    +     ++  +TD E LEA++ L   EG+     S+ +
Sbjct: 266 PETLATAIRIGNPANWDKAWAASRESNGEFHPVTDAEILEAYRILAAEEGVFCEPASAAS 325

Query: 355 LAHALKMMRENPDKEQLLVVNLSGRGDKDIF 385
           +A  LK   + P     +V  L+G G KD  
Sbjct: 326 VAGLLKQKDQVPAG-ATVVCVLTGNGLKDPD 355


>UniRef50_Q5WD43 Threonine synthase n=4 Tax=Bacillus RepID=Q5WD43_BACSK
          Length = 376

 Score =  190 bits (484), Expect = 6e-47,   Method: Composition-based stats.
 Identities = 66/320 (20%), Positives = 119/320 (37%), Gaps = 29/320 (9%)

Query: 70  NTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLK 129
              +Y+K + L+   + K          A  +G T +IA+  +G  G A +  +A  G+ 
Sbjct: 86  KPNVYVKVDYLMPTLSFKDRGAAVLIAKALELGATSVIAD-SSGNAGTAVSAYAARAGIA 144

Query: 130 CRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLG 189
           C ++              +M    A+V  +    A  ++    A +  + + E   +   
Sbjct: 145 CEVFCSNT---VSPKKQAQMAAYNAKVHTI----AGTREDVARAAQQKAANLEEGGFYAS 197

Query: 190 TAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETN 249
               P+ Y     E  +    E   Q+    G  PD VI  VG G+  +G +  F     
Sbjct: 198 HVYNPYFY-----EGTKTYAYEIYEQL----GDAPDTVIIPVGNGTLLLGAYYGFSELLA 248

Query: 250 VGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSV 309
             LIG  P    ++  +  APL H        +   + QT    I E  +I+A    P  
Sbjct: 249 NRLIGKCPKIVAVQAQQ-CAPLAHAFATGEPSITPIVGQT---TIAEGIAIAA---PPRA 301

Query: 310 GPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKE 369
                 + +TG   ++++++ +  +A   L   +G      S+   A AL + R      
Sbjct: 302 TQILEAVRNTG-GTFITVSEAQIAKARSALAK-QGFDVEPTSAATYA-ALHVYRHCE--T 356

Query: 370 QLLVVNLSGRGDKDIFTVHD 389
           + +V+ L G G K    +  
Sbjct: 357 ETIVIPLCGSGTKASDHIAK 376


>UniRef50_UPI0000519DB2 PREDICTED: similar to CG8129-PB, isoform B n=1 Tax=Apis mellifera
           RepID=UPI0000519DB2
          Length = 475

 Score =  190 bits (484), Expect = 6e-47,   Method: Composition-based stats.
 Identities = 65/330 (19%), Positives = 107/330 (32%), Gaps = 40/330 (12%)

Query: 51  NYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAET 110
            Y    T   K   ++      LYLK++ L   G+ K        ++     K   +   
Sbjct: 79  KYDIVNTPCVKS-RLSDAIGVDLYLKKDFLQVTGSFKERGARYALMMLTDEQKKLGVVSA 137

Query: 111 GAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDAC 170
             G H  A +     LG+   + M       +   +   R  GA VI        +++A 
Sbjct: 138 SCGNHAAAISYHGYKLGIPVTVVMPVIAPVIK---IIACRQYGANVII---HGPDMEEAR 191

Query: 171 NEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIAC 230
             ALR  +G  +   Y+ G     + +P IV   Q  +G E   Q+        DAV+  
Sbjct: 192 RTALR--TGKEKGLIYING-----YDHPDIV-AGQGTLGLEIVEQVP-----NIDAVVIP 238

Query: 231 VGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQT 289
           +GGG    G+     +    V +IGVE         E        R        +     
Sbjct: 239 IGGGGLIAGVALAVKSLHPGVMIIGVE--------SEMCPSFYRARKAGRPTYTS----- 285

Query: 290 EDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPAL 349
                    +++ GL  P VG       +      V + +D    A   L   +  I   
Sbjct: 286 ------VGPTLAEGLAVPVVGYNAFATANPLVDKVVVVREDWIAVAILKLLEDDKCIVEG 339

Query: 350 ESSHALAHALKMMRENPDKEQLLVVNLSGR 379
             +  LA  L    E    +++++    G 
Sbjct: 340 AGAIGLAAILAGQLEELRGKRVVLPLSGGN 369


>UniRef50_B9JX06 Threonine dehydratase n=16 Tax=Alphaproteobacteria
           RepID=B9JX06_AGRVS
          Length = 416

 Score =  190 bits (484), Expect = 6e-47,   Method: Composition-based stats.
 Identities = 69/339 (20%), Positives = 123/339 (36%), Gaps = 35/339 (10%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK-TEIIAETGAGQH 115
           T L   ++++   N  +YLKREDL    ++K             +G+  +I     AG H
Sbjct: 20  TPLQLSEHLSTLFNANIYLKREDLTPVRSYKVRGAYNFFRKVIALGQIDKIFVCASAGNH 79

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
               A A    G+   ++M     +++   + + R  GAE I +        D C +A R
Sbjct: 80  AQGFAFACRHFGVHGVVFMPVTTPQQK---IDKTRKFGAEFITIRLVGDIF-DQCYKAAR 135

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
           D+    +      G    P  +  I  E Q  +  E   Q+ E     PD VI  VGGG 
Sbjct: 136 DYVEEAD------GLMVPPFDHADI-IEGQATVAAEILEQLSEEV--TPDLVIMPVGGGG 186

Query: 236 NAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQI 294
            + GM      +      +  EP G           L+ G V     +   +      +I
Sbjct: 187 LSAGMTGYLAEDLPLSAFLFAEPVGAPSL----KRSLEAGEVITLPKVDNFVDGAAVARI 242

Query: 295 EESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHA 354
            ++                A L     A  + + ++        +   EG++     + A
Sbjct: 243 GDAN--------------FAALKHFPPAQVMLVPENAICGTIIDMLNVEGVVLEPAGALA 288

Query: 355 LAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
           +A    + R + + + +++V  SG G+ D   + D+ + 
Sbjct: 289 IATLGLLERSSIEGKTVVLVV-SG-GNFDFERLPDVKER 325


>UniRef50_Q9CKJ2 Threonine dehydratase biosynthetic n=145 Tax=Bacteria
           RepID=THD1_PASMU
          Length = 513

 Score =  190 bits (483), Expect = 7e-47,   Method: Composition-based stats.
 Identities = 62/339 (18%), Positives = 105/339 (30%), Gaps = 37/339 (10%)

Query: 40  EFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAK 99
           E+             + T L     ++      +++KRED     + K            
Sbjct: 14  EYLKAVLSSKVYDVAQVTPLQDMAKLSERLGNKVFIKREDRQPVHSFKLRGAYAMIAGLS 73

Query: 100 RMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPV 159
              K   +    AG H    AL++  LGL+  I M       +   V  +R  G EV+  
Sbjct: 74  AEQKASGVIAASAGNHAQGVALSAKHLGLRALIVMPQNTPSIK---VDAVRGFGGEVLL- 129

Query: 160 HSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILER 219
               A   +A  +A+               T   P  +P  V   Q  I  E   Q    
Sbjct: 130 --HGANFDEAKAKAIELAESKN-------MTFIPPFDHPA-VIAGQGSIAMELLQQ---- 175

Query: 220 EGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIY 279
                D +   V       G          +  +  E    G+E+ +     +  + G  
Sbjct: 176 -NSQIDRIFVPV------GGGGLAAGIAVLIKQLMPEIKVIGVESKDSACLYRALKAGK- 227

Query: 280 FGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTL 339
                P+     G        + G+    +G +   +      D V +  DE   A K +
Sbjct: 228 -----PIDLDRVGLF------ADGVAVKRIGDETFRVCQQYIDDVVLVDGDEICAAVKDI 276

Query: 340 CLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSG 378
             +   I     + +LA   K ++E+  + + LV  LSG
Sbjct: 277 FENVRAIAEPSGALSLAGLKKYVKEHNIQGETLVNVLSG 315


>UniRef50_C1N5N0 Cysteine synthase n=1 Tax=Micromonas pusilla CCMP1545
           RepID=C1N5N0_9CHLO
          Length = 385

 Score =  190 bits (483), Expect = 8e-47,   Method: Composition-based stats.
 Identities = 74/367 (20%), Positives = 125/367 (34%), Gaps = 29/367 (7%)

Query: 53  AGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEI---IAE 109
               T + + ++++  T   + +K E    GG+ K    L     A   G+      I E
Sbjct: 1   MIGNTPMQRVESLSRLTGCDVLIKCEFANPGGSVKDRVALRIVREALASGELRPGGEITE 60

Query: 110 TGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNV-----FRMRLMGAEVIPVHSGSA 164
             AG  GV+ AL +A LG K R       +     +        M   GA    V   S 
Sbjct: 61  GTAGSTGVSVALVAAALGCKARRPARRCSIHWFPYDRVRVKPQMMASFGATTRRVRPVSI 120

Query: 165 T-----LKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILER 219
           +     +K A   A+   +   + A Y     A         R      G E   Q+  R
Sbjct: 121 SHPEHYVKIARQRAMDACARDGKGAGY----FANQFENAANFRAHLDGTGPEIWRQMGGR 176

Query: 220 EGRLPDAVIACVGGGSNAIGMFADFI-NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGI 278
            G + DA +   G G    G+       +  V    V+P G  +    +   +       
Sbjct: 177 RGGV-DAFVCAAGTGGTLAGVSRYLRSKDPRVQFFLVDPPGSSLYNKVNRGVMYCKEEAE 235

Query: 279 YFGMKAPMMQTEDG----QIEESYSISAGLDFPSVGPQHAY-----LNSTGRADYVSITD 329
              +K P     +G    ++  ++SI+ G D    G          L ++  A     +D
Sbjct: 236 GTRLKNPFDTITEGVGINRLTANFSIALGGDGSEAGTSAPVEGVEPLETSPIARAFKCSD 295

Query: 330 DEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLL-VVNLSGRGDKDIFTVH 388
            EA+E  + L   +G+     S   +  A+K+ R      +++ +   SG      F   
Sbjct: 296 REAVEMSRYLAREDGLFLGASSCVNVVGAVKVARALGPGHRVVTIACDSGVRHLTKFWSP 355

Query: 389 DILKARG 395
           + L+  G
Sbjct: 356 EYLEKHG 362


>UniRef50_B9J9P9 Threonine dehydratase protein n=49 Tax=Alphaproteobacteria
           RepID=B9J9P9_AGRRK
          Length = 354

 Score =  190 bits (482), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 69/370 (18%), Positives = 112/370 (30%), Gaps = 41/370 (11%)

Query: 30  EAFVSAQKDPEFQA----QFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGA 85
             F   + DP        +      +   R T L     +       L++K E L H G+
Sbjct: 21  RDFPQQKSDPSMVDIAMIEAARARIDGRARRTPLLSSPFLDEIAGRRLFVKAECLQHTGS 80

Query: 86  HKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPN 145
            K           +   +   +    +G H    ALA+ L G+   I M +   + +  N
Sbjct: 81  FKFRGGWSAVSALEPSVRARGVIAFSSGNHAQGVALAAQLHGIPAVIIMPSDAPKLKIAN 140

Query: 146 VFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQ 205
               R +GAEV+          +      R+             T   P   P  V   Q
Sbjct: 141 T---RALGAEVVLYDRVKEDRDEIGARLSRERG----------LTLIKPFDEPQ-VIAGQ 186

Query: 206 RMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINE-TNVGLIGVEPGGHGIET 264
              G E   Q  E        ++   GGG    G+            +   EP       
Sbjct: 187 GTTGLEIAEQAAEEGIDTATVLV-PCGGGGLTSGIALALEARAPGFKVRPCEPKNF---- 241

Query: 265 GEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADY 324
            +    L  G++      +   +Q          SI   +  P  G     +        
Sbjct: 242 EDTTRSLVSGQI-----ERNAALQG---------SICDAIITPQPGNITFPILKRLCGPG 287

Query: 325 VSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDI 384
           + +TD+EAL+A +       I+     + ALA AL   +E       ++   SG G+ D 
Sbjct: 288 LVVTDEEALDAMELAFKRLKIVVEPGGAVALAAALFHGKEIDGD--TVIAVTSG-GNVDT 344

Query: 385 FTVHDILKAR 394
                 L+  
Sbjct: 345 DVFEAALRRH 354


>UniRef50_C4LUI9 Threonine dehydratase, putative n=4 Tax=Entamoeba
           RepID=C4LUI9_ENTHI
          Length = 429

 Score =  190 bits (482), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 57/329 (17%), Positives = 105/329 (31%), Gaps = 39/329 (11%)

Query: 54  GRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAG 113
              T L    +I+A     +Y K E++   G+ K   V+ +        K   +    +G
Sbjct: 48  IHHTPLDSNASISADIGMDVYFKLENMQKSGSFKVRGVMNKFNSLTLAEKKRGVIAASSG 107

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
            HG+A A     LG+   I +              M+  GA VI        +  A  EA
Sbjct: 108 NHGMAVAYCGKQLGVPTTIIVPNFT---NPRRAETMKRYGATVIL-----HGVTVAEAEA 159

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
                 + +   Y+             +      +G E    + +      DA+IA +G 
Sbjct: 160 YAKEMSTEKRLAYIEA------RDDVSIIAGDGTVGLEILRDLPD-----VDAIIAPIGS 208

Query: 234 GSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDG 292
           GS   G+       +  V + GV+            A L          +     Q ED 
Sbjct: 209 GSLLCGLALAVKTLDPRVKVYGVQ------NEKGSSAYLSKK-----HHVLCRTHQNEDN 257

Query: 293 QIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESS 352
           ++ +           ++G    ++  +   D +++ + +   A   L     +I     +
Sbjct: 258 ELTDV--------VNTIGNLTLHMIESYVDDIITVDETQITRAMMLLMERCKVIIEGAGA 309

Query: 353 HALAHALKMMRENPDKEQLLVVNLSGRGD 381
            ALA  L          ++ V+   G  +
Sbjct: 310 VALAGLLSKKLPIEKGSKVAVIVSGGNVN 338


>UniRef50_P87131 Cysteine synthase 2 n=16 Tax=Ascomycota RepID=CYSK2_SCHPO
          Length = 395

 Score =  189 bits (481), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 63/384 (16%), Positives = 134/384 (34%), Gaps = 31/384 (8%)

Query: 22  MPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLL 81
           M  LR+L E+    +   +   +            T + + ++++  T   +  K E L 
Sbjct: 19  MYLLRRLYESL-RVKSSADSLEEDIVNGVEGLIGNTKMVRIKSLSQATGCDILAKAEFLN 77

Query: 82  HGGAHKTNQVLGQALLAKRMG-----KTEIIAETGAGQHGVASALASALLGLKCRIYMGA 136
            G + K    L     A+  G     ++  + E  AG  G++ A+    LG   RIYM +
Sbjct: 78  PGNSPKDRVALQMIRTAEENGDLVPYQSNAVYEGTAGSTGISIAMLCCSLGYDSRIYMPS 137

Query: 137 KDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSY--ETAHYMLGTAAGP 194
              + +S     + L+GA V  V        +      R  + ++  + +    G  A  
Sbjct: 138 DQSKEKS---DILELLGAHVQRVTPAPIVDPNHFVNTARRNAANHTVDESIPGKGYFANQ 194

Query: 195 HPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFI-NETNVGLI 253
              P   +      G E   Q   +     DA IA  G G    G+       + ++ + 
Sbjct: 195 FENPANWQAHFNSTGPEIWRQCAGKL----DAFIAGSGTGGTIAGISRYLKSKDPSITVC 250

Query: 254 GVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEE-SYSISAGLDFPSVGPQ 312
             +P G G+               +  G+   + + E  +      +I  G+    +   
Sbjct: 251 LADPPGSGLYHK------------VLHGVMFDLAEREGTRRRHQVDTIVEGVGINRMTRN 298

Query: 313 HAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLL 372
            + +          +TD++A+   + L  H+G+     S+     A+++ ++     +++
Sbjct: 299 FS-IAEPLIDMAYRVTDEQAVAMSRYLVTHDGLFVGSSSAVNCVAAVRLAKKLGPGHRIV 357

Query: 373 -VVNLSGRGDKDIFTVHDILKARG 395
            ++   G          + L+ + 
Sbjct: 358 TLLCDPGSRHFSKLYNEEFLRKKN 381


>UniRef50_D0LAQ5 Threonine dehydratase n=6 Tax=Actinomycetales RepID=D0LAQ5_GORB4
          Length = 457

 Score =  189 bits (480), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 81/390 (20%), Positives = 131/390 (33%), Gaps = 43/390 (11%)

Query: 18  PQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKR 77
           P+ +     +L    +          +   L    A   T L  C  I+A T   ++LKR
Sbjct: 5   PETVPEHPSELTADAI----------EAASLRIAPAVIRTPLEACPRISASTGAQIHLKR 54

Query: 78  EDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAK 137
           EDL    ++K            R      +    AG H    A A   +G+  RIY+   
Sbjct: 55  EDLQSVRSYKIRGAYNVMAQLSRSELDRGVVAASAGNHAQGVAYACRTMGVHGRIYVPTT 114

Query: 138 DVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPY 197
             +++   +      G E + + +   T   A   A  D   +         T       
Sbjct: 115 TPKQKRDRISW---HGGEFVELLAVGDTYDAAAAAAQADVLRTGA-------TWIHAFDD 164

Query: 198 PTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFI-NETNVGLIGVE 256
           P      Q  I  E   Q+    GR+PD V+A VGGG    GM   F     +V ++GVE
Sbjct: 165 PR-TAAGQGTIAFEIVDQL----GRVPDVVVAPVGGGGCLAGMVTYFRARRPDVAIVGVE 219

Query: 257 PGGHGIETGE--HGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHA 314
           P G    T    HG P     +  +    A       G    +   +A  D P++     
Sbjct: 220 PTGAISLTAALVHGGPYTLPTIDPFVDGAAVKRIGSIGHGVLAGMGAAVSDHPALAEVPV 279

Query: 315 Y-----------LNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMR 363
           +               G      + +     A   L  +EGII     + A+A   ++  
Sbjct: 280 HSTTRVLTDDPIEVHAGTTHITHVDEGAICSAMLELYQNEGIIAEPAGALAVAALDRLR- 338

Query: 364 ENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
                +  +   +SG G+ D+    +I++ 
Sbjct: 339 --LPADATVACLVSG-GNNDVSRYGEIIER 365


>UniRef50_D0NAZ0 Serine racemase, putative n=1 Tax=Phytophthora infestans T30-4
           RepID=D0NAZ0_PHYIN
          Length = 326

 Score =  189 bits (480), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 60/336 (17%), Positives = 107/336 (31%), Gaps = 44/336 (13%)

Query: 58  ALTKCQNITAGTNT--TLYLKREDLLHGGAHKTNQVLGQA-----LLAKRMGKTEIIAET 110
                ++I AG  +   L+ K E+L   GA K    L           +           
Sbjct: 20  TCHALESIAAGNGSPQRLFFKCENLQRVGAFKYRGALNAVKKYLQEKGESDKTDTTFVTH 79

Query: 111 GAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDAC 170
            +G H  A +LA+     K  I M       +   V   R  GAEV+   S +   + A 
Sbjct: 80  SSGNHAQALSLAARDANCKAVIVMPNNSPSVKQNAV---RGYGAEVLLCESTNEAREKAA 136

Query: 171 NEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIAC 230
           N+ +                   P   P  V   Q  +  E   Q  +  G   DA++  
Sbjct: 137 NDVVEATGAR----------FVHPSNDPD-VMSGQGTVALELLEQAKQEYGVELDAIVVP 185

Query: 231 VGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQT 289
           +GG     G+     + +  + +  VEP G              G  G            
Sbjct: 186 IGGAGLCSGVAMAAKSIQPGIKVFAVEPTGAADAYNSFQKRQLTGHTG------------ 233

Query: 290 EDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPAL 349
                    +++ GL   ++G  +  +      + + ++DD+ + A K +      +   
Sbjct: 234 ------PVNTVADGLRT-TLGDNNWPVVRDFVDEIILVSDDDIVSAMKLIWERMKSVVEP 286

Query: 350 ESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIF 385
             +   A A  +  + P     + +  SG G+ D+ 
Sbjct: 287 SGAV--AAAAVLAHKLPAGITNVGIVFSG-GNVDLE 319


>UniRef50_A5VDD7 Cysteine synthase n=28 Tax=cellular organisms RepID=A5VDD7_SPHWW
          Length = 332

 Score =  189 bits (480), Expect = 2e-46,   Method: Composition-based stats.
 Identities = 68/344 (19%), Positives = 108/344 (31%), Gaps = 42/344 (12%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG---KTEIIAETGAG 113
           T L + +  +  T   +  K E +  GG+ K    L     A+  G      II E  AG
Sbjct: 17  TPLVRLKGPSEATGCEILAKCEFMNPGGSVKDRAALAIITDAEERGLIAPGGIIVEGTAG 76

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
             G+  AL     G +  I M     + +      +R +GAE++ V   + +        
Sbjct: 77  NTGIGLALVGNARGYRTIIVMTDTQSQEKQ---DTLRALGAELVLVPPTAYSNPAHYVHT 133

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
            R  +     A +     A             R    E  AQ     G   D     VG 
Sbjct: 134 SRRIAEETPGALW-----ANQFDNTANRLAHIRTTAPEIWAQ----TGGRIDGFTCAVGT 184

Query: 234 GSNAIGMFADFINETNVGLIG-VEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDG 292
           G    G+       +   +IG  +P G  +        LK     +  G+          
Sbjct: 185 GGTLAGVGLGLKAFSEDVVIGLTDPYGAALFNYFAHGELKAEGSSVAEGI---------- 234

Query: 293 QIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESS 352
                                A L+         ++D+E LE    L   EG+   L S 
Sbjct: 235 ---------------GQSRITANLDGAPVDTQFRVSDEEGLEQVIALLGSEGLCVGLSSG 279

Query: 353 HALAHALKMMRE-NPDKEQLLVVNLSGRGDKDIFTVHDILKARG 395
             +A A+ + +E  P K  + ++  SG            L+A+G
Sbjct: 280 INVAGAIALAKELGPGKTIVTILCDSGMRYLSSLFNPAWLEAKG 323


>UniRef50_C9N4U4 Pyridoxal-5'-phosphate-dependent protein beta subunit n=3
           Tax=Streptomyces RepID=C9N4U4_9ACTO
          Length = 327

 Score =  189 bits (480), Expect = 2e-46,   Method: Composition-based stats.
 Identities = 59/351 (16%), Positives = 108/351 (30%), Gaps = 46/351 (13%)

Query: 43  AQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG 102
                         T L + +         +  K E      + K    L     A+R G
Sbjct: 19  RPAVASRIEELVGSTPLLELRLRDLAPGARVLAKLEFANPMSSSKDRAALYMMRAAERRG 78

Query: 103 K---TEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPV 159
                  + E  +G  G++ A  +A  G +C I +           V  +R  GAE++  
Sbjct: 79  ALLPGGTVIEATSGNTGISLAAFAASRGYRCVIVLPDNATT---ERVKLLRAFGAEIVQT 135

Query: 160 HSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILER 219
            S       A  EA R  + +  +           H     VR      G E  +  +  
Sbjct: 136 PSALG-YPGAIAEAERLHAATPGSWFPC------QHENQDNVRAHYETTGPEIHS-AVAA 187

Query: 220 EGRLPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGI 278
            G    A +  VG G    G+       + +V +I VEP    I +  +    +H   G+
Sbjct: 188 TGSRIAAFVCAVGTGGTLTGIARHLKEQDPDVRVIAVEPEKSPILSQGYAG--QHRIPGL 245

Query: 279 YFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKT 338
             G  A                                  +   + ++++D++AL   + 
Sbjct: 246 NGGFVAETTDV-----------------------------SLIDEVLTVSDEDALVTARR 276

Query: 339 LCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHD 389
           L + +G+   + S  A   +  + R       ++V  L   G++ +     
Sbjct: 277 LAISQGLFAGVSSGAAAYASEVVARRPELTGSVVVTLLPDTGERYLSMWES 327


>UniRef50_Q2YY67 Threonine dehydratase catabolic n=139 Tax=Bacteria RepID=THD2_STAAB
          Length = 346

 Score =  189 bits (480), Expect = 2e-46,   Method: Composition-based stats.
 Identities = 67/354 (18%), Positives = 118/354 (33%), Gaps = 46/354 (12%)

Query: 44  QFNDLLKNYAGRPTALTKCQNITA-GTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG 102
           +          R T L K   ++   T   ++LK E++   G+ K      +        
Sbjct: 20  EEAKASIKPFIRRTPLIKSMYLSQSITKGNVFLKLENMQFTGSFKFRGASNKINHLTDEQ 79

Query: 103 KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSG 162
           K + I    AG H    AL + LLG+   I M     + +       +  G +VI     
Sbjct: 80  KEKGIIAASAGNHAQGVALTAKLLGIDATIVMPETAPQAKQ---QATKGYGTKVILKGKN 136

Query: 163 SATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGR 222
               +    E  ++             T   P+     V   Q  IG E    I      
Sbjct: 137 FNETRLYMEELAKE----------NGMTIVHPYD-DKFVMAGQGTIGLEILDDIWNVN-- 183

Query: 223 LPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFG 281
               VI  VGGG    G+     +   ++ +IGV+                        G
Sbjct: 184 ---TVIVPVGGGGLIAGIATALKSFNPSIHIIGVQSENV-------------------HG 221

Query: 282 MKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCL 341
           M     + +  +     +I+ G D    G Q   +      +++ + ++E   A K L  
Sbjct: 222 MAESFYKRDLTEHRVDSTIADGCDVKVPGEQTYEVVKHLVDEFILVIEEEIEHAMKDLMQ 281

Query: 342 HEGIIPALESSHALAHALKMMRENPDK---EQLLVVNLSGRGDKDIFTVHDILK 392
              II     + AL  A  +  +  +K   ++ +V  +SG G+ D+  V  +++
Sbjct: 282 RAKIITE--GAGALPTAAILSGKINNKWLEDKNVVALVSG-GNVDLTRVSGVIE 332


>UniRef50_C5LC28 Cysteine synthase n=2 Tax=Perkinsus marinus ATCC 50983
           RepID=C5LC28_9ALVE
          Length = 368

 Score =  189 bits (479), Expect = 2e-46,   Method: Composition-based stats.
 Identities = 64/353 (18%), Positives = 109/353 (30%), Gaps = 35/353 (9%)

Query: 50  KNYAGRPTALTKCQNITAGT--NTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG---KT 104
                  T L +  +I+        +Y K E +  GG+ K          A+  G     
Sbjct: 16  WWALVGNTPLIRIDSISELLAVGCDVYAKCEFVNPGGSAKDRVAKMIVADAEEKGQLKAG 75

Query: 105 EIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSA 164
             I E  +G  G++  +A    G K  I+M     + +S     +  +G EV      S 
Sbjct: 76  GTIYEGTSGSTGISLTMAGLARGYKTVIFMPDDQAKEKS---ELIETLGGEVHLCRPVSI 132

Query: 165 TLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLP 224
              +   +     +       Y     A      +  R      G+E   Q         
Sbjct: 133 VDPEHMCKLAEKAAEEDPGGFY-----ADQFENESNFRAHFLGTGKEVLEQTK----GKV 183

Query: 225 DAVIACVGGGSNAIGMFADFI---NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFG 281
           DA +   G G    G  A       +  V +I  +P G  +    +   L + R    + 
Sbjct: 184 DAFVTAAGTGGTLAGTAARLKSELGDDRVTVILADPPGSALARRINTGVLFNERDKEGYR 243

Query: 282 MKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCL 341
           ++ P     +G      + +  L  P                 VSI+D EA+   + L  
Sbjct: 244 VRHPFDTVTEGIGLGRLTHNFTLGLPF------------IDHAVSISDTEAVRMSRWLLR 291

Query: 342 HEGIIPALESSHALAHALKMMREN---PDKEQLLVVNLSGRGDKDIFTVHDIL 391
            +G+      S  +A  +K  +     P +  + +V  SG      F     L
Sbjct: 292 EDGLFVGSSGSLNVAAVVKAYKRGYIKPGQRVVTIVCDSGMRHLSKFWNDAYL 344


>UniRef50_Q2S090 Threonine dehydratase n=6 Tax=cellular organisms RepID=Q2S090_SALRD
          Length = 470

 Score =  189 bits (479), Expect = 2e-46,   Method: Composition-based stats.
 Identities = 68/366 (18%), Positives = 119/366 (32%), Gaps = 43/366 (11%)

Query: 28  LEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHK 87
           +      +    + +A    L      R T +  C +++  +     LK E L   G+ K
Sbjct: 61  IPRILPMSVTIDDVRAARERLDDPSVVRKTPIDSCHSLSELSGAVAILKMEHLQRTGSFK 120

Query: 88  TNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVF 147
           T     +       G    +    AG H    ALA+  + L   I M     + +   V 
Sbjct: 121 TRGAYNKLAQV-ASGTVGRVVAASAGNHAQGVALAATTVDLPSTIVMPRNAPQAK---VD 176

Query: 148 RMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRM 207
             R  GA+V        T ++A   A R+ +   +            +  P IV   Q  
Sbjct: 177 ATRGYGADVELT---GDTFQEAMTRA-RELARGDDALF------VHAYDDPDIV-AGQGT 225

Query: 208 IGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGE 266
           +G E   Q+ +      D VIA +GGG    G      +   +V ++GV+  G       
Sbjct: 226 LGFELYEQVPD-----VDTVIAPIGGGGLIGGTSMALADIAPDVRVVGVQAAG----AAT 276

Query: 267 HGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVS 326
               L  G                   +    +I+ G+    V      L      + ++
Sbjct: 277 VPQSLAKGVPV---------------PVNHPDTIADGIATGGVSALTLGLIDDHVDEVIT 321

Query: 327 ITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFT 386
           +TD E   A   L      +     +  +A    +  +     + +V  L G G+ D   
Sbjct: 322 VTDGEIARAILLLLERAKQLVEGAGAAPVAAL--LSDKLDVTGETVVPLLCG-GNIDPAR 378

Query: 387 VHDILK 392
           + ++L 
Sbjct: 379 LQEVLD 384


>UniRef50_D1IAP7 Whole genome shotgun sequence of line PN40024,
           scaffold_7.assembly12x (Fragment) n=3 Tax=Magnoliophyta
           RepID=D1IAP7_VITVI
          Length = 606

 Score =  188 bits (478), Expect = 3e-46,   Method: Composition-based stats.
 Identities = 73/329 (22%), Positives = 110/329 (33%), Gaps = 39/329 (11%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           + L     ++      ++LKREDL    + K            +      +  + AG H 
Sbjct: 124 SPLQLAPKLSERLGAQIWLKREDLQPVFSFKLRGAYNMMAKIPKEQLERGVICSSAGNHA 183

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD 176
              ALA+  LG    I M     E +  +V R   +GA V+ V        D+ +EA   
Sbjct: 184 QGVALAAKRLGCNAVIAMPVTTPEIKWKSVER---LGATVVLV-------GDSYDEAQAY 233

Query: 177 WSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSN 236
                E       T   P  +P  V   Q  IG E   Q+        DA+   VGGG  
Sbjct: 234 AKQRGEEE---CRTFIPPFDHPD-VIMGQGTIGMEIVRQMQGPL----DAIFVPVGGGGL 285

Query: 237 AIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIE 295
             G+ A        V +IGVEP     +       L H +          +M  + G   
Sbjct: 286 IAGIAAYVKRVSPEVKIIGVEP----CDANAMALSLHHDQR---------VMLDQVGGF- 331

Query: 296 ESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHAL 355
                + G+    VG +   L        V ++ D    + K +   +  I     + AL
Sbjct: 332 -----ADGVAVKVVGEETFRLCRELIDGIVLVSRDAICASIKNMFEEKRSILEPAGALAL 386

Query: 356 AHALKMMRENPDKEQLLVVNLSG-RGDKD 383
           A A    +    K   +V   SG   + D
Sbjct: 387 AGAEAYCKYYGIKGGNIVAITSGANMNFD 415


>UniRef50_D0N4G9 Cysteine synthase n=2 Tax=Phytophthora infestans T30-4
           RepID=D0N4G9_PHYIN
          Length = 394

 Score =  188 bits (477), Expect = 4e-46,   Method: Composition-based stats.
 Identities = 57/327 (17%), Positives = 105/327 (32%), Gaps = 28/327 (8%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG---KTEIIAETGAG 113
           T L +   ++  T   L  K E     G+ K        L A+  G       I E   G
Sbjct: 50  TPLLELTTLSKLTGCKLLAKAEYANPSGSIKDRVAKSLILDAEERGLLKPGGTIIEATGG 109

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKD-ACNE 172
             GV+ AL  A  G K  + M     + +   V  M+ MGA+V  + + S + K+     
Sbjct: 110 STGVSLALLGASRGYKTLLTMPDITAKEK---VQMMKTMGAQVHVLPTTSMSDKENHFFH 166

Query: 173 ALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVG 232
                + +   A+               +         E  +Q+        D  +   G
Sbjct: 167 VAARLAETTPNAYCP-----NQFDNIANMMAHYEGTAPEIWSQVNGEI----DGFVTSAG 217

Query: 233 GGSNAIGMFADFINET-NVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTED 291
                 GM   F  +  +V +  ++P      +             I  G +   M    
Sbjct: 218 TSGTIAGMSRFFKKKKSDVKVWLIDPEETAAMSAFINN--DRSTSTIEDGFEVVPM---- 271

Query: 292 GQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALES 351
               +  +I+ G+   ++      L  +     ++  + E +     L  ++GI     S
Sbjct: 272 ---AKGATIAEGVA--ALSRVTQNLRESIVDKGITANNQEIVGMAYFLLRNDGIFVGPSS 326

Query: 352 SHALAHALKMMRENPDKEQLLVVNLSG 378
           +  +  A+KM RE      ++ +   G
Sbjct: 327 ALNVLGAVKMARELGPGHTIVTILADG 353


>UniRef50_A0LG82 L-threonine ammonia-lyase n=2 Tax=cellular organisms
           RepID=A0LG82_SYNFM
          Length = 416

 Score =  188 bits (477), Expect = 4e-46,   Method: Composition-based stats.
 Identities = 73/356 (20%), Positives = 117/356 (32%), Gaps = 43/356 (12%)

Query: 39  PEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLA 98
           P    +  + LK    R T L      +      +YLK E+L   G+ K      + +  
Sbjct: 12  PSVIRKAAEALKGRVLR-TPLVYSSTFSRLCGAKVYLKLENLQETGSFKLRGATWKIMSN 70

Query: 99  KRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIP 158
                 + +    AG H    ALA++   L   + M               R  GAEVI 
Sbjct: 71  LHRIGPDGVVAASAGNHAQGVALAASRAKLPSTVIMPE---WASISKQEATRNYGAEVII 127

Query: 159 VHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILE 218
                 +L DA  +A +              T   P   P  V   Q  IG E   ++ E
Sbjct: 128 ---EGQSLSDAIRKAGQLVERGK--------TLIHPFDDPD-VMAGQGTIGLEILEELPE 175

Query: 219 REGRLPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVG 277
                PD V+  VGGG    G+     +      ++GV+              L+ GRV 
Sbjct: 176 -----PDLVVVPVGGGGLIGGIAVACRSVRPETRIVGVQAQACP----SACRSLESGRVV 226

Query: 278 IYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFK 337
                K               S++ G+    VG     +      + V + +D    A  
Sbjct: 227 SVEAQK---------------SLADGITVKQVGALPFAVMKEMVDEIVLVEEDAIAAAVL 271

Query: 338 TLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
            L   + ++     +  LA  +    E P    +++V  SG G+ D   +  +L+ 
Sbjct: 272 MLLERKKLLAEGAGAVPLAALMSCSFEVPKGGTVVLVI-SG-GNMDSPLLGRVLRK 325


>UniRef50_B5H9V7 Threonine synthase n=4 Tax=Streptomyces RepID=B5H9V7_STRPR
          Length = 371

 Score =  187 bits (476), Expect = 4e-46,   Method: Composition-based stats.
 Identities = 67/364 (18%), Positives = 116/364 (31%), Gaps = 44/364 (12%)

Query: 22  MPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLL 81
              L +L     S  +  E     + +     GR T L            T+ +K + L 
Sbjct: 43  PVPLTELPGRVNSLWRYAEALPLTDPVTSLGEGR-TPLVPLTG-------TVSVKLDFLT 94

Query: 82  HGGAHKTNQVLGQALLAKRM-GKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVE 140
              + K    +  A LA+R+ G    +    +G  G A A   A  GL C +++      
Sbjct: 95  PTLSFKDRGAVMLAELARRLPGPPRRVIADSSGNAGTAVAAYCARAGLDCTVFVPEATSA 154

Query: 141 RQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTI 200
           ++   V ++R  GA +  V                  + +   A    G     H Y   
Sbjct: 155 KK---VEQIRAHGARLELVPGDREA-----------TAEAARAAAGGEGVFYASHVYNPF 200

Query: 201 VREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGH 260
                +    E    +    GRLP+A++  VG G+  +G           GLI   P   
Sbjct: 201 FLHGTKTYVYELWEDL---GGRLPEAIVVPVGNGTLLLGAAQALTELHEHGLIESRPALI 257

Query: 261 GIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLN--S 318
            ++             G              G+     +++ G+  P+       L    
Sbjct: 258 AVQAEAVSPLAAAFHAGAD---------DLLGRSPARPTLAEGIAIPNPPRARQILRAVR 308

Query: 319 TGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSG 378
                ++++T+DE  +A + L    G+     +  A   A          ++  VV L G
Sbjct: 309 EWGGTFLTVTEDEIRQARRDLAGR-GLFVE-STGVACWAAA-----GGWTDRTAVVPLCG 361

Query: 379 RGDK 382
            G K
Sbjct: 362 AGLK 365


>UniRef50_A6GXZ8 Cysteine synthase/cystathionine beta-synthase family protein n=23
           Tax=Bacteroidetes RepID=A6GXZ8_FLAPJ
          Length = 355

 Score =  187 bits (476), Expect = 5e-46,   Method: Composition-based stats.
 Identities = 62/348 (17%), Positives = 110/348 (31%), Gaps = 41/348 (11%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE---IIAETGAG 113
           T L K   IT G     Y K E    G + K    L     A++ G  +    I ET +G
Sbjct: 27  TPLIKIDKITEGLKGNFYAKVEAFNPGHSTKDRIALYIIEEAEKQGILKPGDTIIETTSG 86

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
             G + A+ S + G  C     A   +  +  +  +R MGA+V    +  +    A +E 
Sbjct: 87  NTGFSLAMVSIIKGYDCIF---AISSKSSADKIDMLRSMGAKVYVCPAHVS----ADDER 139

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
                                +     +    +  G E   Q           +IAC G 
Sbjct: 140 SYYSVAKRLHEEIKGSVYINQYFNHLNIEAHYKSTGPEIWEQ----TNGKITHLIACTGT 195

Query: 234 GSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDG 292
           G    G+         N+ ++GV+  G  I+                  +    ++    
Sbjct: 196 GGTISGIAKFLKEKNPNIRILGVDAYGSVIKKYHETKEFDK------DEIYPYRIEGLGK 249

Query: 293 QIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESS 352
            +  S      LDF                 +V +TD+E+    + +   EG+     S 
Sbjct: 250 NLIPS-----ALDF------------DLIDKFVKVTDEESAHMTRNIAKVEGLFVGYTSG 292

Query: 353 HALAHALKMMRENPDKEQL-LVVNLSGRGDKDIFTV--HDILKARGEI 397
             +    +   E    E+  ++      G + +  V   + ++A+G  
Sbjct: 293 AVVQAIKQYAEEGEFDEKSNIIAIFPDHGSRYMSKVFNEEWMEAQGFF 340


>UniRef50_Q02145 Threonine dehydratase biosynthetic n=83 Tax=Bacteria
           RepID=THD1_LACLA
          Length = 416

 Score =  187 bits (476), Expect = 5e-46,   Method: Composition-based stats.
 Identities = 61/351 (17%), Positives = 108/351 (30%), Gaps = 34/351 (9%)

Query: 43  AQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG 102
               DLLK      T L     ++      +YLK E+L    + K               
Sbjct: 8   EDAYDLLKA-VVTKTPLQLDPYLSNKYQANIYLKEENLQKVRSFKLRGAYYSISKLSDEQ 66

Query: 103 KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSG 162
           +++ +    AG H    A A+  L +   I+M      ++   V   +  G E       
Sbjct: 67  RSKGVVCASAGNHAQGVAFAANQLNISATIFMPVTTPNQKISQV---KFFG-ESHVTIRL 122

Query: 163 SATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGR 222
                D    A + +S   +           P      V   Q  +  E  AQ  ++   
Sbjct: 123 IGDTFDESARAAKAFSQDNDKPF------IDPFD-DENVIAGQGTVALEIFAQAKKQGIS 175

Query: 223 LPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGM 282
           L    +   GGG  A              +IGVE  G       + A             
Sbjct: 176 LDKIFVQIGGGGLIAGITAYSKERYPQTEIIGVEAKGATSMKAAYSA------------- 222

Query: 283 KAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLH 342
                  +   +E     + G+   +VG +   L +      +++ +    +    L   
Sbjct: 223 ------GQPVTLEHIDKFADGIAVATVGQKTYQLINDKVKQLLAVDEGLISQTILELYSK 276

Query: 343 EGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
            GI+     + ++A    +  E   K   +V  +SG G+ DI  + +I + 
Sbjct: 277 LGIVAEPAGATSVAALELIKDEIKGKN--IVCIISG-GNNDISRMQEIEER 324


>UniRef50_B4AUD2 Threonine synthase, putative n=23 Tax=Francisella
           RepID=B4AUD2_FRANO
          Length = 598

 Score =  187 bits (475), Expect = 6e-46,   Method: Composition-based stats.
 Identities = 70/334 (20%), Positives = 115/334 (34%), Gaps = 29/334 (8%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T L K + I       LY K E     G+ K         +AK +G   I+     G   
Sbjct: 75  TPLLKSKIIGKELGINLYFKVEGKNPTGSFKDRGSAVDITVAKELGAKGIVLA-STGNMA 133

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD 176
            + A  +A   + C I +       +   V      G +++ V           NEA + 
Sbjct: 134 ASCACYAAAAKMPCFIIVPEGVAASKLAQVM---SYGGKIVQVKGS-------YNEAAKL 183

Query: 177 WSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSN 236
                ++  + L              E Q+    E   Q+     ++PD VI  +G G+N
Sbjct: 184 AYDIAKSKDFFLAG------DYAFRVEGQKTAAFELIDQL---LFQVPDEVIIPIGCGTN 234

Query: 237 AIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEE 296
               +  F     +G I   P   G+++ E    L          ++             
Sbjct: 235 MTAYYKGFCEYKELGFINSLPKLTGVQSTE-ADTLARAYQKNQNRIEPLKT-------AN 286

Query: 297 SYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALA 356
           + + +  + +P  G +      +   +  ++TD + LEA   L   EG+   L S+  +A
Sbjct: 287 TIATAIAVPYPIDGDKAIDAIYSTGGESTAVTDMKMLEAQYLLSTKEGLFVELASASTIA 346

Query: 357 HALKMMRENP-DKEQLLVVNLSGRGDKDIFTVHD 389
           H LK   E    K   +V  LSG G KD   V  
Sbjct: 347 HLLKKYEEGRLQKGSTVVCVLSGEGLKDPGVVLK 380


>UniRef50_A4RXR0 Predicted protein n=16 Tax=cellular organisms RepID=A4RXR0_OSTLU
          Length = 387

 Score =  187 bits (474), Expect = 7e-46,   Method: Composition-based stats.
 Identities = 58/348 (16%), Positives = 101/348 (29%), Gaps = 36/348 (10%)

Query: 36  QKDPEFQAQFNDLLKNYA--GRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLG 93
           ++D         + +N       T + K   +       +Y+K E      + K    + 
Sbjct: 22  RRDRARTTPRARIYENILETVGDTPVIKVNRLAPA-GIDMYVKCEYFNPLSSVKDRLAVA 80

Query: 94  QALLAKRMGKTE---IIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMR 150
               A+R G  +    + E  +G  G+A A+A A  G +C I M              MR
Sbjct: 81  VITDAERRGLLKPGDTVVEATSGNTGIAVAMACAQRGYRCVICMAEP---FSVERRKIMR 137

Query: 151 LMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGE 210
           ++GA+VI    G             + +       ++                     G 
Sbjct: 138 MLGAKVIVTPKGGKGTGMVAK--AEELAEK--NGWFLCR----QFENEANPAYHASTTGP 189

Query: 211 ETKAQILEREGRLPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHG- 268
           E         G+  D  +   G G    G+         +  +I +EP    + T     
Sbjct: 190 EILRDF---AGKKLDYFVTGYGTGGTFQGVARTLKESRPDTKVILLEPEAAALVTSGIKT 246

Query: 269 -APLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSI 327
                    G +    A  +Q                           LN     + V I
Sbjct: 247 ERKPTGAPNGSHPAFAAHPVQGWTPDFIPLV-------------LENGLNMNLYDELVKI 293

Query: 328 TDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVN 375
              +A++  + L   EGI   +      A ALK+  + P    +L + 
Sbjct: 294 EGGDAVKTAQALARSEGIFTGISGGATFAGALKVAEKAPKGSVILAML 341


>UniRef50_A2FH13 Pyridoxal-phosphate dependent enzyme family protein n=2
           Tax=Trichomonas vaginalis RepID=A2FH13_TRIVA
          Length = 417

 Score =  187 bits (474), Expect = 8e-46,   Method: Composition-based stats.
 Identities = 63/360 (17%), Positives = 111/360 (30%), Gaps = 35/360 (9%)

Query: 34  SAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLG 93
             + + E   +  + ++ YA   T      N++  T+  LY K E L    A K    L 
Sbjct: 3   ELRVNLEKIKEAKERIRPYAV-ETPCNFVPNLSKITDCQLYFKLETLQRCRAFKFRGALS 61

Query: 94  QALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMG 153
           +        K   I    AG H    AL++ + G+KC +YM       +   V   R  G
Sbjct: 62  KISTLP---KGSTIVCASAGNHSQGCALSAQICGMKCIVYMPITAPITK---VDATRGYG 115

Query: 154 AEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETK 213
           AEV        +  +A  +   D + + +           P      V   Q  IG E  
Sbjct: 116 AEVRQY---GFSFDEANKKCAEDLAANPDWIF-------VPPFDSDEVIAGQGTIGLEIA 165

Query: 214 AQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKH 273
            Q+ + +  +               G          +  +  +     +      A    
Sbjct: 166 QQVPDVDTVVV-----------AVGGGGLAAGTAVAIKALCPKARVIAVNAAVRPASYLK 214

Query: 274 GRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEAL 333
            +      +         G        + G+   + G            D+V +T+DE  
Sbjct: 215 YKNFKGQEIDQNTTTKFIGNPL-----ADGIAVINPGKVTFPYIEQLVDDFVVVTEDEIS 269

Query: 334 EAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
            A   L     +I     +   A  L    E    E+++ V LSG G+ ++  +   +  
Sbjct: 270 TAIAYLAERTKMICEGAGASPFAAVLFKKFEYRPDEKIVCV-LSG-GNIELPMLARCIDR 327


>UniRef50_C1SG53 Threonine dehydratase, medium form n=1 Tax=Denitrovibrio
           acetiphilus DSM 12809 RepID=C1SG53_9BACT
          Length = 398

 Score =  186 bits (473), Expect = 9e-46,   Method: Composition-based stats.
 Identities = 63/356 (17%), Positives = 118/356 (33%), Gaps = 45/356 (12%)

Query: 39  PEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLA 98
            +    +  + K+    P  L    N +      +Y K E+L   G+ K    L   L  
Sbjct: 3   EDITKAYFRIRKHIKHLP--LYYSNNFSERLGGDVYFKLENLQRTGSFKIRGALNCILK- 59

Query: 99  KRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIP 158
                   +    AG H    A ++  +G++  I M       +   V   +  GAEVI 
Sbjct: 60  HEDKCRNGVIAASAGNHAQGVAFSAKSMGIRAVIVMPEFTPMVK---VNSTKGHGAEVIL 116

Query: 159 VHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILE 218
                 + +DA   A+       E   +       P      V   Q  +  E   +  +
Sbjct: 117 Y---GESFEDAYKHAVE--ISEKEGLFF-----VHPFDDTD-VIAGQGSVAYEVLNENPD 165

Query: 219 REGRLPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVG 277
                 D ++  VGGG    G+       ++++ +IGV+      E     + L  GRV 
Sbjct: 166 I-----DQIVVPVGGGGLVSGVAEYVKGFDSSIKVIGVQAS----EAAGMVSSLSEGRVV 216

Query: 278 IYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFK 337
                           +  S + + G+    VG            + V++T+ E      
Sbjct: 217 ---------------SLSTSSTFAEGIAVKKVGELTLKHCQNCVDELVTVTESEIALGVL 261

Query: 338 TLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
                  ++     +  LA    +  +   K +  V+ +SG G+ D+ T++ ++  
Sbjct: 262 EFMERSKLVVEGAGAAPLAAV--LAEKIDVKNKTTVLVVSG-GNIDVTTINRVINR 314


>UniRef50_A5EK00 L-threonine synthase n=11 Tax=Bacteria RepID=A5EK00_BRASB
          Length = 413

 Score =  186 bits (473), Expect = 1e-45,   Method: Composition-based stats.
 Identities = 63/333 (18%), Positives = 119/333 (35%), Gaps = 33/333 (9%)

Query: 57  TALTKCQNITAGTNT-TLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
           T L     ++       + +K E  L  G+ K   ++    + K +G T +   T     
Sbjct: 90  TPLINLPKLSKKLGGGEIIVKDEGRLPTGSFKARGLVMAVSMGKALGITHMAMPTNGN-A 148

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
           G A A  +   G+K  I+  A   E    NV  + L GA V  V+     L D C + + 
Sbjct: 149 GAALAAYATSCGIKTTIFCPADTPEV---NVSEIELQGATVYRVNG----LIDDCGKIVG 201

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
           +         +   T   P+       E ++ +G E   Q+      +PD +    GGG+
Sbjct: 202 EGKAKV--GWFDTSTLKEPYR-----IEGKKTMGLELAEQL---GWDVPDVIFYPTGGGT 251

Query: 236 NAIGMFADFINETNVGLIG-VEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQI 294
             IGM+  F     +G IG   P    ++       ++    G+    +           
Sbjct: 252 GLIGMWKAFDELEKIGFIGSKRPRMVAVQASGCAPMVRAYEAGVEHATRWE--------- 302

Query: 295 EESYSISAGLDFPSVGPQHAYLN--STGRADYVSITDDEALEAFKTLCLHEGIIPALESS 352
            ++++I++G+  P        L      +   +++ DD+   A   +   EG++   E +
Sbjct: 303 -DAHTIASGIRVPQAVGDFLILRAVRESKGFAIAVDDDKISSALSEVAREEGLLLCPEGA 361

Query: 353 HALAHALK-MMRENPDKEQLLVVNLSGRGDKDI 384
              A   + +      K   +++     G K  
Sbjct: 362 ATYAAYKQSLADGRVTKNDRVMLFNCATGLKYP 394


>UniRef50_B0AA90 Cysteine synthase n=4 Tax=Firmicutes RepID=B0AA90_9CLOT
          Length = 303

 Score =  186 bits (473), Expect = 1e-45,   Method: Composition-based stats.
 Identities = 56/318 (17%), Positives = 106/318 (33%), Gaps = 50/318 (15%)

Query: 64  NITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG---KTEIIAETGAGQHGVASA 120
           N+       +++K E    GG+ K    L     A+  G   K  ++ E  +G  G+A A
Sbjct: 22  NLKEAGYPNVFVKLEKANPGGSIKDRAALYMINGAEEKGILNKDSVLVEATSGNTGIALA 81

Query: 121 LASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGS 180
           +A  L G K  I M              ++  GAE++    G+  +  +  +A       
Sbjct: 82  MAGKLKGYKVIIIMPDTM---SIERRQLVKAFGAELMLTE-GAKGMAGSIEKANELL--- 134

Query: 181 YETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGM 240
            +  +Y+     G        R      G E   ++ +        ++A +G G   +G 
Sbjct: 135 DKNPNYIC---LGQFDNEDNPRAHYETTGPEILKEVKDVS-----FIVAGIGSGGTIVGA 186

Query: 241 FADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYS 299
                     + +IG+EP    + T     P K              +Q           
Sbjct: 187 GKFLKEKNKEIKVIGIEPKSSPLITENKSGPHK--------------IQGIGANFIP--- 229

Query: 300 ISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHAL 359
                            +       ++++D+++ E  + +    GI+  + S   +  A+
Sbjct: 230 --------------KIYDKDIVDKVITVSDEDSYETVRLIANKLGILIGISSGANIFGAM 275

Query: 360 KMMRENPDKEQLLVVNLS 377
           K+  ENPDK  + V    
Sbjct: 276 KLSDENPDKIIVTVAPDG 293


>UniRef50_Q15NS2 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit n=5
           Tax=Bacteria RepID=Q15NS2_PSEA6
          Length = 338

 Score =  186 bits (472), Expect = 1e-45,   Method: Composition-based stats.
 Identities = 63/348 (18%), Positives = 112/348 (32%), Gaps = 43/348 (12%)

Query: 45  FNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKT 104
              L  +   R + L     +       +  K E L   GA K    L   L AK  G  
Sbjct: 11  AARLRISRYVRTSELMTSALLNRWLGHEILFKTECLQRTGAFKLRGALNTLLHAKEKGVP 70

Query: 105 -EIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGS 163
            + +  + +G H  A A A++L  +   I+                R  GAE+       
Sbjct: 71  IKRVVASSSGNHAQAVAYAASLFDIPATIF---SAQNISKIKAAATRAYGAELRLFP--- 124

Query: 164 ATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRL 223
             L+D  + A+   +    T          P  +P  V   Q  +  E   Q  +  G  
Sbjct: 125 --LRDEADNAVAQAANEPGTLW------IPPFNHPD-VIAGQGTVTAEILEQTADVNG-- 173

Query: 224 PDAVIACVGGGSNAIG-MFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGM 282
              +    GGG  A G M A         +I  EP    +   +    L+ G +      
Sbjct: 174 ---IFMPCGGGGLASGSMLAARALSPQTKVIASEP----LAGNDAAQSLRLGSIQRL--- 223

Query: 283 KAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLH 342
                      I  + +++ G   P VG     L       +  + + +     + L   
Sbjct: 224 -----------ITPAKTLADGAATPVVGEHTYPLIQQ-LDGFYEVDETQIAYWTQWLQHL 271

Query: 343 EGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDI 390
             +     S+ ++   +  + +    ++++V+ LSG G+ D   +  I
Sbjct: 272 LKLHVEPTSAMSMHGVVNYLAKQSAPQKVVVI-LSG-GNIDAQKMQQI 317


>UniRef50_C1E0J2 Predicted protein n=1 Tax=Micromonas sp. RCC299 RepID=C1E0J2_9CHLO
          Length = 477

 Score =  185 bits (471), Expect = 2e-45,   Method: Composition-based stats.
 Identities = 67/338 (19%), Positives = 109/338 (32%), Gaps = 36/338 (10%)

Query: 57  TALTKCQNITAGTNTT----LYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGA 112
           T +     + A         L +K E  L  G+ K   ++    +AK +G T + A    
Sbjct: 143 TPIVDAPKLAAEAGLEEGGALLVKDEGRLPTGSFKARGLVMAVSMAKELGVTRM-AMPTN 201

Query: 113 GQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNE 172
           G  G A +   +  G++  I+      +    N+  M L GA V  V+            
Sbjct: 202 GNAGAAMSAYCSRCGIETYIFAPEDTPDT---NIREMALQGANVWRVNGYIDDCGKIVG- 257

Query: 173 ALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVG 232
                 G  E   +   T   P+       E ++ +G E   Q       LPD ++   G
Sbjct: 258 -----GGKEEMNWFDTSTLKEPYR-----IEGKKTMGLELVEQFG--WDDLPDVIMYPTG 305

Query: 233 GGSNAIGMFADFINETNVGLIGVE---PGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQT 289
           GG+  IGM+  F     +GLI  E   P    ++       +     G  F  +     T
Sbjct: 306 GGTGLIGMWKAFGELKELGLIKPETKLPKMVAVQATGCAPMVNAYDAGEEFATRVDNAFT 365

Query: 290 EDGQIEESYSISAGLDFPSVGPQHAYLN--STGRADYVSITDDEALEAFKTLCLHEGIIP 347
                      + G+  P+       L          V++TDD   E        EG + 
Sbjct: 366 RS---------AMGIRVPAAVGDFLILRAVRESGGWAVAVTDDAIDEGQTEFAKKEGFLL 416

Query: 348 ALESSHALAHALK-MMRENPDKEQLLVVNLSGRGDKDI 384
             E +   A   K +      K   +++     G K  
Sbjct: 417 CPEGAATYAAFKKGLANGKIKKTDRVLLFNCATGLKYP 454


>UniRef50_A0D3F4 Chromosome undetermined scaffold_36, whole genome shotgun sequence
            n=5 Tax=cellular organisms RepID=A0D3F4_PARTE
          Length = 1531

 Score =  185 bits (471), Expect = 2e-45,   Method: Composition-based stats.
 Identities = 69/340 (20%), Positives = 115/340 (33%), Gaps = 39/340 (11%)

Query: 53   AGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGA 112
                T   K   ++      +Y+KREDL    ++K      + +      +   +  + A
Sbjct: 1134 VITRTPTQKSMKLSEQFGANVYIKREDLQIVRSYKLRGAYNKIISIPESERHRTVFCSSA 1193

Query: 113  GQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNE 172
            G H    A    LL + C IYM       +   V   +  G + + +     T  ++   
Sbjct: 1194 GNHAQGVAYVCNLLKINCIIYMPTNTPSIKFNAV---KSWGKQYVQIELVGDTFDESF-R 1249

Query: 173  ALRDWSGSYETAHYMLGTAAGPHPYPTI-VREFQRMIGEETKAQILEREGRLPDAVIACV 231
            A RD   + E   Y+       H +    + E Q  I  E    I E      D V   V
Sbjct: 1250 ASRD-RCNTENGIYV-------HAFDDEKIIEGQGTIAVEILEDIPE---SKIDFVFFPV 1298

Query: 232  GGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTE 290
            GGG    G+ + F     +  LIGVEP G                          + Q +
Sbjct: 1299 GGGGCGAGISSYFKQINPDTILIGVEPEGSPSMYEA-------------------IKQQK 1339

Query: 291  DGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALE 350
              ++E   +   G      G +   + ++   D V I +         L   EGI+    
Sbjct: 1340 VVELETINTFVDGAAIKKSGAKPFEILNSVLKDIVLIPEGHVCTTMMKLFNEEGILVEPA 1399

Query: 351  SSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDI 390
             + A++   +   E   K   +V  +SG  + D+  + DI
Sbjct: 1400 GALAISALDRFKDEIRGK--TVVCLISGS-NNDLGRMTDI 1436


>UniRef50_Q5K9M8 Threonine ammonia-lyase, putative n=6 Tax=cellular organisms
           RepID=Q5K9M8_CRYNE
          Length = 590

 Score =  185 bits (470), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 70/330 (21%), Positives = 113/330 (34%), Gaps = 40/330 (12%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T LT   N++A     +++KREDL    + K               K + +    AG H 
Sbjct: 90  TPLTYAANLSARLGNEIWIKREDLQPVFSFKIRGAYNMMASLSDEEKKKGVITCSAGNHA 149

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD 176
              AL+   L +   + M       +  NV   + +GA V+          +A  E LR 
Sbjct: 150 QGVALSGHALNIPAIVVMPVSTPSIKWRNV---QRLGATVLL---HGRDFDEAKAECLRL 203

Query: 177 WSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSN 236
                        T   P+  P  V   Q  +  E   Q+ +      D + A VGGG  
Sbjct: 204 EKEKG-------LTFVPPYDNP-YVVAGQGTVAMEICRQVTDA--DQIDGIFASVGGGGL 253

Query: 237 AIGMFADFIN--ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQI 294
           A G+ A      + +VG+ GVE     ++       LK G+          ++  E G  
Sbjct: 254 AAGIAAYMKRVAKPSVGIYGVET----VDGDAMDRSLKAGKR---------VLLDEVGPF 300

Query: 295 EESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHA 354
                 + G     VG +   +      D V + +DE   A K +      +P    + A
Sbjct: 301 ------ADGTAVRLVGEEPFRVCKNFLDDVVLVNNDEICAAIKDVFEETRSVPEPSGALA 354

Query: 355 LAHALKMMREN---PDKEQLLVVNLSGRGD 381
           LA     +  N      ++ + V   G  +
Sbjct: 355 LAGLKAHIIRNNLQGAGKRFVAVISGGNMN 384


>UniRef50_UPI00006CA830 Pyridoxal-phosphate dependent enzyme family protein n=1
           Tax=Tetrahymena thermophila RepID=UPI00006CA830
          Length = 322

 Score =  185 bits (469), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 62/343 (18%), Positives = 115/343 (33%), Gaps = 43/343 (12%)

Query: 45  FNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKT 104
            +  +K Y  + T +  C ++       LY K E+   GG+ K+       L   +  K 
Sbjct: 18  AHQKIKPYIHQ-TPIITCTSLNQLVGADLYFKCENFQKGGSFKSRGAANAILSLSKEQKK 76

Query: 105 EIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSA 164
             +    +G HG A A  + +  +   I M       +  +V   +  G ++I   +  A
Sbjct: 77  NGVGTHSSGNHGGALARMAQIFQIPSYIIMPFDAPNSKKRSV---QNYGGKIIECGATIA 133

Query: 165 TLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLP 224
             +    +  ++                 P+     V + Q  I  E   QI     +  
Sbjct: 134 DREGTLEKTRKETGCE----------IVHPY-NDYRVIKGQGTIALEIYQQIQ----KPL 178

Query: 225 DAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMK 283
           D +I  VGGG    G+         +  +I  EP        +    L  G+V   F   
Sbjct: 179 DFIITPVGGGGLLSGILIASKAISPSTKVIAAEP----FLARDAYLSLISGKVEPQF--- 231

Query: 284 APMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHE 343
                          +I+ G+   ++G +   +        + + + E ++A   +    
Sbjct: 232 ------------PPKTIADGIR-ANLGDKTFDIIKDKCDGILLVEEQEIVDATNLIWQRM 278

Query: 344 GIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFT 386
            II    S+  LA  +K       K   + + L+G G+ DI  
Sbjct: 279 KIIVEPTSATVLAAVIKNKELFKGKS--IALVLTG-GNTDIEY 318


>UniRef50_A6GJR2 Cysteine synthase n=1 Tax=Plesiocystis pacifica SIR-1
           RepID=A6GJR2_9DELT
          Length = 315

 Score =  185 bits (469), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 59/330 (17%), Positives = 106/330 (32%), Gaps = 44/330 (13%)

Query: 53  AGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE-----II 107
           A   T L   + +  G    +Y+K E L  GG+ K          A+  G         +
Sbjct: 7   AIGDTPLLPLERLARGLPNPVYVKCEHLNPGGSVKDRLARAIVDDAEARGVLRPHAGMTL 66

Query: 108 AETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLK 167
            E  AG  G+  AL +A  G      M  K    +   +  M   GA V+   +   +  
Sbjct: 67  IEATAGNTGMGLALVAAARGYALVCVMPEKMSVDKRRALAAM---GARVVVTKNAPPSSP 123

Query: 168 DACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAV 227
           D      R  +   +   ++          P  V       G E   Q+    GR P A 
Sbjct: 124 DNFQNVARRMAE--DEGWFLT----EQFDNPVNVEVHAATTGPEILRQL----GRAPAAF 173

Query: 228 IACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPM 286
           ++  G G    G+       + +  ++  +P G G+        +  G +G         
Sbjct: 174 VSGAGTGGTISGVGRCLKRADPSTRVVLADPVGSGL-----AGWVATGEMG--------- 219

Query: 287 MQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGII 346
                         +  ++        A L+     + VSI+D+ +    + L   EG++
Sbjct: 220 -----------PDGAYAVEGIGSSKAPANLHRAVIDEAVSISDERSFATARALIREEGML 268

Query: 347 PALESSHALAHALKMMRENPDKEQLLVVNL 376
               +   +A AL++         ++ V  
Sbjct: 269 VGGSAGTNVAAALELAARPELGGPVVTVLC 298


>UniRef50_B0TB97 Threonine dehydratase n=13 Tax=Firmicutes RepID=B0TB97_HELMI
          Length = 413

 Score =  185 bits (469), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 53/337 (15%), Positives = 101/337 (29%), Gaps = 37/337 (10%)

Query: 56  PTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQH 115
            T   +    +  +   ++LK E++   G+ K    L + L      +   +    AG H
Sbjct: 29  HTPFEQSATFSRLSGRDVWLKCENMQRTGSFKIRGALNKILSLTEEERARGVIAASAGNH 88

Query: 116 GVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALR 175
               AL ++L+G+   I M       +   V   R  GA+VI          +   E  R
Sbjct: 89  AQGVALGASLIGVPATIVMPKGAPLAK---VEATRDYGAQVILHGDFYDEAYEHAQELRR 145

Query: 176 DWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGS 235
                +  A                V   Q  +G E   Q+        D ++       
Sbjct: 146 RTGAVFIHAF-----------DDPQVIAGQGTLGLEILEQMR--PIGAFDGIVLP----- 187

Query: 236 NAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIE 295
              G          V  +  E    G++     A     ++  +  +             
Sbjct: 188 -IGGGGLAGGLALAVKSLHPEMRIVGVQAESAPAMALSKKLHTHTVVACKA--------- 237

Query: 296 ESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHAL 355
              +I+ G+     G     L      + +++ D+   +    L     ++        L
Sbjct: 238 ---TIADGIAVSCPGNLTFSLIEQLVDEIITVNDESIAKTMTLLLERSKLVVEGSGVIGL 294

Query: 356 AHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILK 392
           A  L+       + +     LSG G+ DI  +  I++
Sbjct: 295 AALLE--ERVGRRGERWAALLSG-GNIDISAIARIIE 328


>UniRef50_A9V280 Predicted protein n=4 Tax=cellular organisms RepID=A9V280_MONBE
          Length = 488

 Score =  185 bits (469), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 48/304 (15%), Positives = 94/304 (30%), Gaps = 40/304 (13%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHG 116
           T +   Q +       L+ K E    GG+ K    L          +   +    +G H 
Sbjct: 26  TPVLTSQQMDRRAGLQLHFKCETFQKGGSFKIRGALNAISKLPDDVRD--VVTHSSGNHA 83

Query: 117 VASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRD 176
            A ALA  L G    I M       +   V      GA VI   S     +         
Sbjct: 84  QAVALACQLTGRNAHIVMPDNAPAVKRAAVV---DYGARVITCESTQPARE--------- 131

Query: 177 WSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSN 236
            + +  T   +  +A  P      V   Q  +  E   Q+        DA+I  +GGG  
Sbjct: 132 -AAAEATRAALPKSALIPPYDHCDVIAGQGTMALELLEQVPGL-----DALIVPIGGGGM 185

Query: 237 AIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIE 295
             G+         ++ +I  EP        +    ++  +  +                 
Sbjct: 186 LAGICLAAKGIRPDIKVIAAEPA----RADDCYQSIRDQQHVLLKTY------------- 228

Query: 296 ESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHAL 355
              +++ GL   S+G  +  +         ++++ + ++  + +     ++    +   +
Sbjct: 229 -PDTVADGLRT-SMGNLNWPIIRDHVDKVFTVSEHDIIQGQRLVMERMKVVIEPSAGVPV 286

Query: 356 AHAL 359
           A A+
Sbjct: 287 AVAM 290


>UniRef50_Q83FN5 Threonine deaminase n=2 Tax=Tropheryma whipplei RepID=Q83FN5_TROWT
          Length = 427

 Score =  184 bits (468), Expect = 4e-45,   Method: Composition-based stats.
 Identities = 66/349 (18%), Positives = 118/349 (33%), Gaps = 25/349 (7%)

Query: 43  AQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG 102
                ++ +     T + +   ++    + +Y K E+L   G++K   V       K+  
Sbjct: 11  RAAAKVMHSKFVVHTPVIQSVMLSDLVGSPVYFKCENLQITGSYKIRGVFNYLHNLKK-- 68

Query: 103 KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSG 162
           ++  +    AG H  + A A+  +G+K  I+M         P     +  GAE+I     
Sbjct: 69  RSTAVVAASAGNHAQSVAYAAKQIGIKAVIFMP---SSVSLPKYNATKKYGAEIILDQGD 125

Query: 163 SATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGR 222
             TL     +A R                  P  +  IV   Q  I  E   Q+ +    
Sbjct: 126 IQTL---ILKARRYAKKHK-------FVFIPPFDHRDIVV-GQGTIALELLEQVPDLR-- 172

Query: 223 LPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGM 282
               V+   GGG    G+ +      N         G   +  + G  +   +       
Sbjct: 173 ---TVVVPTGGGGLVAGIASAVTLAQNPSGTIFTKSGLE-QPAKSGIRVVGVQAKTSASF 228

Query: 283 KAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLH 342
              M+  +  ++  +   + G+  P  G     L       +V + D E   A  TL   
Sbjct: 229 IESMVAGKPVKVNITSHFADGIAVPKPGKITFELARCFVDRFVEVGDHEIAGAILTLLED 288

Query: 343 EGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDIL 391
             II       A A A  + ++  + +   V+ LSG G+ D  T+  I+
Sbjct: 289 SKIIVEPA--AASAAAAVLSKKITNLKGSTVIVLSG-GNIDPMTLSQII 334


>UniRef50_A2BKW1 Threonine synthase n=1 Tax=Hyperthermus butylicus DSM 5456
           RepID=A2BKW1_HYPBU
          Length = 366

 Score =  184 bits (468), Expect = 5e-45,   Method: Composition-based stats.
 Identities = 68/320 (21%), Positives = 108/320 (33%), Gaps = 33/320 (10%)

Query: 70  NTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLK 129
              ++ K E L   G+ K          A RMG   ++ E  +G  G++ A  +A  GL+
Sbjct: 79  GVRVFFKLEYLNPTGSFKDRGTSLALAYASRMGF-RLVVEDTSGNTGISVAAYAAAYGLR 137

Query: 130 CRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLG 189
            RIYM     E +      +R +G EV+   S       A       W        Y+  
Sbjct: 138 ARIYMPVNAPEGKK---RLVRALGGEVVLTPS-RGEAAQAV-----LWELKKPDVFYVA- 187

Query: 190 TAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETN 249
                H +     E  + I  E         G    AV+  VG G   +G++  F     
Sbjct: 188 -----HTWSPFYVEGAKTIAFEAFED-----GFRGSAVLVPVGSGGLLLGIYHGFRELVE 237

Query: 250 VGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSV 309
            GLI   P    ++ G    PL     G     +    +  DG +            P +
Sbjct: 238 QGLIDSVPRIIAVQ-GYSNPPLYRAVYGKEPEAEERSSRLADGLMVSEP--------PRL 288

Query: 310 GPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMREN-PDK 368
           G     + +TG    + + D+      K L    G I    S+      L+ +     DK
Sbjct: 289 GEAAEAVKATGGC-VILVDDEGIRRGLKMLASM-GFIVEPTSATLYPALLEAVERGCIDK 346

Query: 369 EQLLVVNLSGRGDKDIFTVH 388
            + ++  L+G G K +    
Sbjct: 347 GEEVLAPLTGSGLKTLEYFK 366


>UniRef50_C3XUX1 Putative uncharacterized protein n=3 Tax=Branchiostoma floridae
            RepID=C3XUX1_BRAFL
          Length = 1635

 Score =  184 bits (467), Expect = 5e-45,   Method: Composition-based stats.
 Identities = 49/322 (15%), Positives = 95/322 (29%), Gaps = 45/322 (13%)

Query: 70   NTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEI----IAETGAGQHGVASALASAL 125
               +  K E+    G+ K                T      +     G      A+A+ L
Sbjct: 1345 GRRVVFKCENFQKPGSFKFRGACHALSRLVSANGTTPHRLQVVAGSTGNFACGLAMAAEL 1404

Query: 126  LGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAH 185
             G+   + M     E +          GA++                  +D + + +   
Sbjct: 1405 FGVTAHVVMPNNSPECK---RQTALSYGADLTLCEPT-----------AQDIAQTVKQVQ 1450

Query: 186  YMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFI 245
             + G           V      +G E   Q+        DAV+  VG G    G+     
Sbjct: 1451 DVTGAVFISGGNNPDVISGHGTMGLELLRQVPNL-----DAVVMPVGTGGMLSGVSVAIK 1505

Query: 246  N-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGL 304
            +    + + G EP        +    L  G    +                   SI+ GL
Sbjct: 1506 SICPEIRIYGAEPEV----ANDAAMSLSKGERCTFARF--------------PQSIADGL 1547

Query: 305  DFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRE 364
            +  ++GP       +   +  ++++DE   A + +     ++     +  +A  L    +
Sbjct: 1548 N-GNIGPVPWTYIQSYVDNIFTVSEDEIKNATRLVWEKMKLVVEPSGAVGVAAVLSDSFK 1606

Query: 365  NPDKE-QLLVVNLSGRGDKDIF 385
                  + + V LSG G+ D+ 
Sbjct: 1607 AQAGGCRNVAVILSG-GNVDLQ 1627


>UniRef50_Q3ADX2 Cysteine synthase n=10 Tax=cellular organisms RepID=Q3ADX2_CARHZ
          Length = 306

 Score =  184 bits (467), Expect = 5e-45,   Method: Composition-based stats.
 Identities = 66/338 (19%), Positives = 111/338 (32%), Gaps = 49/338 (14%)

Query: 53  AGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG---KTEIIAE 109
               T L K + +T G   T+  K E    GG+ K          A+  G   K  +I E
Sbjct: 10  LIGKTPLLKLKRVTRGVKATVVAKLEYFNPGGSVKDRIAFNMIKAAEEQGLLDKDTVIIE 69

Query: 110 TGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDA 169
             +G  G+  A+ +A  G +  I M              ++  GAE++        +  A
Sbjct: 70  PTSGNTGIGLAMVAAARGYRLIITMPETM---SVERRMLLKAYGAEIVLTPGELG-MTGA 125

Query: 170 CNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIA 229
            N+AL           +           P      ++    E             D V+ 
Sbjct: 126 VNKALELAKE------FPKAFIPQQFENPANPEIHRKTTAIEIWED----TDGQVDIVVG 175

Query: 230 CVGGGSNAIGMFADFI-NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQ 288
            VG G    G+       +  V +I VEP    + +G    P  H   GI  G    +  
Sbjct: 176 GVGTGGTITGVGEVLKAKKPEVKIIAVEPADSPVLSGGKPGP--HKIQGIGAGFVPKV-- 231

Query: 289 TEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPA 348
                                       N     + + +  D+A    K +   EG++  
Sbjct: 232 ---------------------------FNRDVVDEIIQVESDDAFAMAKKIAKEEGVLVG 264

Query: 349 LESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFT 386
           + S  AL  AL++ +   ++ +L+VV L   G++ + T
Sbjct: 265 ISSGAALWAALEVAKRPENEGKLIVVVLPDTGERYLST 302


>UniRef50_D2VDG8 Predicted protein n=1 Tax=Naegleria gruberi RepID=D2VDG8_NAEGR
          Length = 368

 Score =  184 bits (467), Expect = 5e-45,   Method: Composition-based stats.
 Identities = 72/375 (19%), Positives = 125/375 (33%), Gaps = 61/375 (16%)

Query: 42  QAQFNDLLKNYAGRPTALTKCQNITAGTN---TTLYLKREDLLHGGAHKTNQVLGQALLA 98
               ++ ++ Y  + T +     I+  T     TLYLK E+L   GA K        L A
Sbjct: 21  IENASERIRKYIHK-TPVLTNSTISQMTGIPNCTLYLKCENLNKVGAFKIRGACNAVLNA 79

Query: 99  K--------RMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMR 150
                    +  K   +    +G H  A A ++ +LGL   I M +     +   V    
Sbjct: 80  LNNSDEEIVKKIKEGGVITHSSGNHAGALAKSAQMLGLTAHIVMPSNSPAVKKNAVELT- 138

Query: 151 LMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGE 210
             GA VI       + ++ C   +++                 P+     V   Q     
Sbjct: 139 -YGARVILCEPTLRSREETCERIIQETGAL----------FIHPYDNDD-VITGQGTAVL 186

Query: 211 ETKAQILE--REGRLP-DAVIACVGGG-----------SNAIGMFADFINETNVGLIGVE 256
           E   Q+ E       P DA+I  VGGG           S A     D        +IGVE
Sbjct: 187 EMLDQVKEERLTDEFPLDALIVPVGGGGLSSGSSICFKSKAALEIKDLEKLKKTKVIGVE 246

Query: 257 PGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYL 316
           P                   G   G    +          + ++  GL   ++  +  + 
Sbjct: 247 PQVVDDAKRSM-------EQGKLVGNDPNV---------PANTVCDGLKT-NLSERTFHH 289

Query: 317 NSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHAL--KMMRENPDKE--QLL 372
            S       ++TD++ ++A K +     I+    S+  +A  L     ++   +   Q +
Sbjct: 290 ISKNIDRIFTVTDEQVIKAMKLVWERMKIVIEPSSATVVALTLFHDEFKQMATENQWQHI 349

Query: 373 VVNLSGRGDKDIFTV 387
            + +SG G+ D+  +
Sbjct: 350 GMVISG-GNCDLDAL 363


>UniRef50_C4PYD1 Cysteine synthase, putative n=2 Tax=Schistosoma mansoni
           RepID=C4PYD1_SCHMA
          Length = 516

 Score =  184 bits (467), Expect = 6e-45,   Method: Composition-based stats.
 Identities = 67/331 (20%), Positives = 109/331 (32%), Gaps = 43/331 (12%)

Query: 57  TALTKCQNITAG--TNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE---IIAETG 111
           T L +   I         L  K E L  GG+ K          A+  GK +    I E  
Sbjct: 61  TPLIQLDRIAKHEDIECELLGKCEFLNIGGSVKDRIGKRMIEEAELEGKLKPGDTIIEPT 120

Query: 112 AGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACN 171
           +G  G+  AL +AL G +C I M  K    +      +R +GAE++   + +        
Sbjct: 121 SGNTGIGLALTAALKGYRCIIVMSDKMSSEKE---SYLRCLGAEIVRTPASANFDNPD-- 175

Query: 172 EALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGR-LPDAVIAC 230
            +L   S   +            +  P           EE      E  G+   D ++A 
Sbjct: 176 -SLFLVSEKLKNEIGPSAHIMNQYTNPYNPIAHFDETAEEIIRDCTEENGQIKLDMLVAS 234

Query: 231 VGGGSNAIGMFADFI-NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQT 289
           VG G    G+         N  ++GV+P G  +   E      +   GI +     ++ T
Sbjct: 235 VGTGGTIAGLSRKIKMKIPNCLIVGVDPIGSILANPECPETTPYDVEGIGYDFFPTVLDT 294

Query: 290 EDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPAL 349
                                         G   +   +D E+ E  + L   EG+    
Sbjct: 295 -----------------------------NGIDKWCKTSDHESFEMARRLIHEEGLPCGG 325

Query: 350 ESSHALAHALKMMRENP-DKEQLLVVNLSGR 379
            S  A+A A++ +++    K   +VV L   
Sbjct: 326 SSGAAVAGAIRTIKQLGLGKNSRVVVILPDN 356


>UniRef50_Q1ITV7 L-threonine ammonia-lyase n=7 Tax=Bacteria RepID=Q1ITV7_ACIBL
          Length = 413

 Score =  184 bits (467), Expect = 6e-45,   Method: Composition-based stats.
 Identities = 68/356 (19%), Positives = 119/356 (33%), Gaps = 45/356 (12%)

Query: 40  EFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAK 99
           E   Q    ++      +      +I+      +YLK E+L   G+ K    L + L   
Sbjct: 16  ESIEQARARIRADVY-FSPCNHSHSISKIAGQRVYLKLENLQMTGSFKERGALNKILTLS 74

Query: 100 RMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPV 159
              K   +    AG H    +  +   G++ RI M       +   V   R  GAEVI  
Sbjct: 75  NDEKQRGVIAASAGNHAQGVSFHATRHGIRARIVMPMMTPLVK---VNATRGYGAEVIL- 130

Query: 160 HSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPT-IVREFQRMIGEETKAQILE 218
               A   +A  EA R  +         L      HP+    V   Q  I  E   Q  +
Sbjct: 131 --HGADYDEAYEEACRLAA---------LEGLVFIHPFDDPQVIAGQGTIALELLEQAPD 179

Query: 219 REGRLPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVG 277
            E     AV+  +GGG    G+     +   ++ +IGV+            A        
Sbjct: 180 ME-----AVVVPIGGGGLISGIACALKSLRPDIRVIGVQAARMPSMQSALQA-------- 226

Query: 278 IYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFK 337
                       +   I+ + +I+ G+     G    +L  +   + V   ++E      
Sbjct: 227 -----------HKAVTIDSNTTIADGIAVRRSGDLTVHLVESYVDELVVAEEEEIASGIL 275

Query: 338 TLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
           TL   E  +     + A+A  L       +++ + +V     G+ D+  +  I++ 
Sbjct: 276 TLLEREKTLAEGAGAAAVAALLHHKTSLKNEKTVALVCG---GNIDVSLLARIIQR 328


>UniRef50_P53607 Threonine dehydratase biosynthetic n=494 Tax=cellular organisms
           RepID=THD1_BURM1
          Length = 507

 Score =  184 bits (466), Expect = 7e-45,   Method: Composition-based stats.
 Identities = 65/347 (18%), Positives = 108/347 (31%), Gaps = 36/347 (10%)

Query: 39  PEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLA 98
            ++  +            T L   +N++A     +YLKRED     + K      +    
Sbjct: 4   HDYLKKILTARVYDVAFETELEPARNLSARLRNPVYLKREDNQPVFSFKLRGAYNKMAHI 63

Query: 99  KRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIP 158
                   +    AG H    A ++A +G+K  I +     + +   V  +R  G   + 
Sbjct: 64  PADALARGVITASAGNHAQGVAFSAARMGVKAVIVVPVTTPQVK---VDAVRAHGGPGVE 120

Query: 159 VHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILE 218
           V     +  DA   AL+              T   P   P  V   Q  I  E   Q   
Sbjct: 121 VIQAGESYSDAYAHALKVQEERG-------LTFVHPFDDP-YVIAGQGTIAMEILRQHQG 172

Query: 219 REGRLPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVG 277
                  A+   +GGG  A G+ A        + +IGV+      ++      L+ G+  
Sbjct: 173 PI----HAIFVPIGGGGLAAGVAAYVKAVRPEIKVIGVQAE----DSCAMAQSLQAGKRV 224

Query: 278 IYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFK 337
                          ++ E    + G     VG +   L        V++  D    A K
Sbjct: 225 ---------------ELAEVGLFADGTAVKLVGEETFRLCKEYLDGVVTVDTDALCAAIK 269

Query: 338 TLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSG-RGDKD 383
            +      +     + A+A A         + Q LV   SG   + D
Sbjct: 270 DVFQDTRSVLEPSGALAVAGAKLYAEREGIENQTLVAVTSGANMNFD 316


>UniRef50_UPI000180BB5B PREDICTED: similar to Serine racemase n=2 Tax=Ciona intestinalis
           RepID=UPI000180BB5B
          Length = 338

 Score =  184 bits (466), Expect = 7e-45,   Method: Composition-based stats.
 Identities = 56/359 (15%), Positives = 121/359 (33%), Gaps = 45/359 (12%)

Query: 38  DPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALL 97
           D        +++K +  + T L +C  I+      ++LK E+    G+ K          
Sbjct: 17  DFNDVKAAYEIIKPFIHQ-TPLMQCSAISELAGCNVFLKTENFQKTGSFKIRGATNALSH 75

Query: 98  AKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVI 157
           + +    + +    +G HG A A  +  +G+   I M    ++ +      +R  G  ++
Sbjct: 76  SVKEDAIQCVITRSSGNHGQAIAYVAKSMGIPAYIIMSNTALKCKK---DAIRSYGGIIV 132

Query: 158 PVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQIL 217
                    K      L++           + +   PH     V   Q  +  E   Q  
Sbjct: 133 EGKPQLEHRKKITEHLLKE------KGGIFIHSGQNPH-----VIAGQGTLAMEMLEQNP 181

Query: 218 EREGRLPDAVIACVGGGSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRV 276
                  DA++A VGGG    G+          + +  VEP                G++
Sbjct: 182 NL-----DAIVAPVGGGGLISGVAIAAKALKPYIKIYAVEPE----NANGCYLSKLSGKL 232

Query: 277 GIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAF 336
               G +A              +I+ G+   ++G     +      D ++++++E  +A 
Sbjct: 233 EYVVGTEA--------------TIADGVR-ANIGESTWPIIQDLIDDVITVSEEEIKQAT 277

Query: 337 KTLCLHEGIIPALESSHALAHA----LKMMRENPDKEQLLVVNLSGRGDKDIFTVHDIL 391
             +     ++    +   +A      L   +   +  + + + LSG G+ D   +  ++
Sbjct: 278 VLVWERAKLVIEPTAGVGVAAVVGKKLLSAKGFDNSVKNIGLVLSG-GNVDARDIAKLI 335


>UniRef50_D1CDN5 Threonine synthase n=1 Tax=Thermobaculum terrenum ATCC BAA-798
           RepID=D1CDN5_THET1
          Length = 432

 Score =  183 bits (465), Expect = 8e-45,   Method: Composition-based stats.
 Identities = 59/342 (17%), Positives = 112/342 (32%), Gaps = 30/342 (8%)

Query: 47  DLLKNYAGRPTALTKCQNITAGTNTT-LYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE 105
           + +       T L     +        LYLK E     G+ K   +     +A+  G   
Sbjct: 87  EAIITRGEGNTGLYNVPKLADWVGVDTLYLKHEGENPTGSFKDRGMTVGVSVARHCGAA- 145

Query: 106 IIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSAT 165
           I+A    G    + A  +A+  ++C + + A  V     +       GA+ I        
Sbjct: 146 IVACASTGNTSASLASYAAIADMRCVVLLPAGKVSAAKLSQSI--AYGAKTI-------A 196

Query: 166 LKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPD 225
           ++   ++AL     +       +  +  P        E Q+ +  E    +      +PD
Sbjct: 197 IRGDFDKALSLLQSTAPQLGLYILNSVNP-----WRLEGQKTVMYELLESLR---WEVPD 248

Query: 226 AVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAP 285
            +    G   N        +   ++GLI   P   G+   E  AP  H     +      
Sbjct: 249 WIFLPGGNLGNTSAFGKALLEMRSLGLIDSLPRI-GVVQAEGAAPFAHAYKSGWQSYSPV 307

Query: 286 MMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGI 345
             +T    +  +  I   +++         L+        S++D E L+A K +    G+
Sbjct: 308 KAET----VATAIRIGDPVNYQKARRVVQELD----GLVTSVSDREILDA-KAMVDGAGV 358

Query: 346 IPALESSHALAHALKM-MRENPDKEQLLVVNLSGRGDKDIFT 386
                S+ ++A   K+        +  +V  L+G   KD   
Sbjct: 359 GCEPASAASVAGIRKLMSERIISPDSKVVAVLTGHILKDPDA 400


>UniRef50_B3EGT7 Cysteine synthase A n=8 Tax=Bacteria RepID=B3EGT7_CHLL2
          Length = 309

 Score =  183 bits (465), Expect = 8e-45,   Method: Composition-based stats.
 Identities = 71/348 (20%), Positives = 116/348 (33%), Gaps = 50/348 (14%)

Query: 44  QFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG- 102
           +  D +    GR T L +   ++ G    + +K E      + K    +     A++ G 
Sbjct: 2   KIYDNITETVGR-TPLVRLHRLSRGCRADVLVKIESFNPLSSVKDRIAVAMLEDAEKSGM 60

Query: 103 --KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVH 160
                 + E  +G  G+  A A A  G +  + M              M+ +GAE++   
Sbjct: 61  IVPGTTLIEPTSGNTGIGLAFACAAKGYRLMLVMPDTM---SIERRKLMQFLGAELVLTE 117

Query: 161 SGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILERE 220
            GS  +  A  EA R                      P      +     E         
Sbjct: 118 -GSGGMNRAIAEAERLAESIPG------SLILQQFRNPANPAVHRLTTAVEIWED----S 166

Query: 221 GRLPDAVIACVGGGSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIY 279
           G + D  +A VG G    G+  +       V +I VEP    + +G  G P  H   GI 
Sbjct: 167 GGMVDVFVAGVGTGGTITGVGEELKKHKPGVAIIAVEPYDSPVLSG--GQPGPHKIQGIG 224

Query: 280 FGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTL 339
            G                                A LN     + V +T+++A    + L
Sbjct: 225 AGFVP-----------------------------AILNREIIDEIVKVTNEDAGATARRL 255

Query: 340 CLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTV 387
              EGI+  + S  AL  AL + R    + +++VV L   G++ + T 
Sbjct: 256 AAEEGILCGISSGAALYAALGIARREEMEGKMVVVLLPDSGERYLSTW 303


>UniRef50_B5IBS9 Threonine synthase n=2 Tax=Aciduliprofundum boonei T469
           RepID=B5IBS9_9EURY
          Length = 373

 Score =  183 bits (465), Expect = 9e-45,   Method: Composition-based stats.
 Identities = 51/348 (14%), Positives = 106/348 (30%), Gaps = 45/348 (12%)

Query: 37  KDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQAL 96
           +  +F +    +  +     T + +           +YLK E L    + K         
Sbjct: 44  RYRDFYSIPLSMDYSLGEGDTPIIRV----DMYGNEVYLKNETLNPTWSFKDRGTFVAIN 99

Query: 97  LAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEV 156
            A +MG   I      G    + A   A  GL   + + +   + +   + ++   G ++
Sbjct: 100 RAIQMGFERIGV-VSTGNMAASVAAYGAHAGLDTIVLVSSNIPKEK---ISQILPYGTKI 155

Query: 157 IPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQI 216
           + V      L        +          Y + +            E  + I  E     
Sbjct: 156 LKVKGDYGELY------FKSLKIGKMRKIYFMNS------DDPFRVEGYKTIAYELAE-- 201

Query: 217 LEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRV 276
                   D V      G    G++  F+     G+I   P    ++             
Sbjct: 202 ----KVDVDYVFVPTSSGGLFRGVYKGFLELKESGIIDKIPEMVAVQAKGCSPICSAYPS 257

Query: 277 GIYFGMKAPMMQTEDGQIEESYSISAGLD--FPSVGPQHAYLNSTGRADYVSITDDEALE 334
           G            + G+ + + +I+  ++  +P  G     +        +++ +DE ++
Sbjct: 258 G------------KIGRFKNASTIAHAIENPYPPSGNAVLRILKKNGWKCIAVEEDEIIK 305

Query: 335 AFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDK 382
           A + L    GI     S+  LA      ++   K   + + L+G G K
Sbjct: 306 AQEELAYK-GIFVQPASATTLAAL----KKLNLKNTRIALILTGSGLK 348


>UniRef50_Q9F7T0 Predicted threonine dehydratase n=1 Tax=uncultured marine gamma
           proteobacterium EBAC31A08 RepID=Q9F7T0_PRB01
          Length = 513

 Score =  183 bits (465), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 57/346 (16%), Positives = 108/346 (31%), Gaps = 41/346 (11%)

Query: 34  SAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLG 93
           S +   ++     +         + +T   NI++     ++LKREDL    + K      
Sbjct: 10  SFKNSQKYLKLIPNASVYDVALKSPITFALNISSKLGNKVFLKREDLQPIFSFKNRGAYN 69

Query: 94  QALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMG 153
           + +      K   +    AG H    A A   L + C I M     E +  +V   +  G
Sbjct: 70  KIVNLSDAEKKRGVIAASAGNHAQGVASACKKLKINCLIVMPITTPEIKIKDV---KRFG 126

Query: 154 AEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETK 213
           A+++        +  A  EAL               +   P   P +    Q  IG+E  
Sbjct: 127 AKILQ---HGDNVDAALKEALFIAKKKK-------LSFVHPFDDP-LTIAGQGTIGQEIL 175

Query: 214 AQILEREGRLPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLK 272
                 +          +       G+ A        + ++GVE            A   
Sbjct: 176 EDKNNFDVVFVPVGGGGI-----LAGVSAWIAQNNKKIKIVGVEVEDSACLAEAVKA--- 227

Query: 273 HGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEA 332
                            +   ++E    + G+    VG  +  +      + ++++ DE 
Sbjct: 228 ----------------NKRVILKEVGLFADGVAVSRVGKNNFDVIKECVDEVITVSVDEV 271

Query: 333 LEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSG 378
             A K +     ++     + ALA      R+  +K+  L+   SG
Sbjct: 272 CTAVKDIFEDTRVLSEPAGALALAGLKAYARKVKNKK--LIAISSG 315


>UniRef50_C3DBY4 Cystathionine beta-synthase n=2 Tax=Bacillus thuringiensis
           RepID=C3DBY4_BACTU
          Length = 327

 Score =  183 bits (464), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 59/337 (17%), Positives = 112/337 (33%), Gaps = 51/337 (15%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG---KTEIIAETGAG 113
           T + K   +    +  LY+K E    GG+ K          A+  G       I E+ +G
Sbjct: 13  TPIVKINKLVPPESAQLYVKLEGFNPGGSSKDRVAKRVIEYAENSGQLKPGGTIVESSSG 72

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGS--ATLKDACN 171
              +  AL + + G K    +   D +    N+  ++  GA+V  V           A  
Sbjct: 73  NLAIGLALVAKMKGYKMICVV---DPKISKVNLNLIKSYGAQVHMVDVSDEHGNYLKARL 129

Query: 172 EALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACV 231
              +D + S + A++        +  P     +   + +E      +      D ++  V
Sbjct: 130 VIAQDLANSIDGAYWP-----NQYNNPENPEAYVHTLVQEIYDDFNDTL----DWIVCPV 180

Query: 232 GGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTE 290
           G      G+         +V ++ V+  G  I           G+ G+        +   
Sbjct: 181 GTAGLITGVAKGMKKLNPSVKVMAVDAVGSVIFG---------GKPGV------RRLLGI 225

Query: 291 DGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALE 350
              I                     +N +   D   + D +A    + L   EGI+    
Sbjct: 226 GNAIVPGN-----------------VNRSLYDDLSYVNDADAFFITRELVSKEGILVGGS 268

Query: 351 SSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTV 387
           S   +  AL+++ + P K + ++  L  RGD+   T+
Sbjct: 269 SGAVVCAALRLIDKLP-KSKKVLAILPDRGDRYYNTI 304


>UniRef50_C6XK52 Pyridoxal-5'-phosphate-dependent protein beta subunit n=1
           Tax=Hirschia baltica ATCC 49814 RepID=C6XK52_HIRBI
          Length = 319

 Score =  183 bits (464), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 56/342 (16%), Positives = 110/342 (32%), Gaps = 42/342 (12%)

Query: 44  QFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK 103
           +    +  Y  + T +   +         ++ K E+  H GA K    +           
Sbjct: 16  EAAKRIAPYV-KQTPVMTSEKFNQFVGADVFFKCENFQHVGAFKARGAMNAVFALSDEDA 74

Query: 104 TEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGS 163
           +  +    +G H  A  LA+   G+  RI M     + +   + ++R +G ++      +
Sbjct: 75  SYGVVAHSSGNHAAALCLAARNRGISARIVMPENSNKVK---IAQVRELGGQIEFCIPTA 131

Query: 164 ATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRL 223
              + A    + +                 P      V   Q  +  E  +++       
Sbjct: 132 QAREQAAAAIVEETGARL----------IHPF-NDAHVIAGQGSVALELLSEVSGL---- 176

Query: 224 PDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMK 283
            DA++A VGGG    G             I  +    G E  E     +  R G   G  
Sbjct: 177 -DAILAPVGGGGLMSGCAL------TAKAIKPDIFTCGAEPKEVNDAARSLRSGQLQGNV 229

Query: 284 APMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHE 343
                        + SI+ GL    +G     +      + V +++   + A + +    
Sbjct: 230 T------------TNSIADGLR-GDLGQMAFDILKKHLDELVEVSEANIVAAMRFIWSDL 276

Query: 344 GIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIF 385
            II    S+ A+A  +     +  K   + V ++G G+ D+ 
Sbjct: 277 KIIIEPSSAVAIAALM--AERSRIKGDRIGVVITG-GNVDLD 315


>UniRef50_A2FRC0 Threonine dehydratase family protein n=1 Tax=Trichomonas vaginalis
           RepID=A2FRC0_TRIVA
          Length = 418

 Score =  183 bits (464), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 64/351 (18%), Positives = 110/351 (31%), Gaps = 39/351 (11%)

Query: 44  QFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK 103
              + + ++A   T      NI    N  +Y K E +    A K    L +         
Sbjct: 15  AAKERIADHAV-VTPCIDSDNIGHMVNAQIYFKLETMQRCKAFKFRGALNKLRTIPE--- 70

Query: 104 TEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGS 163
              +    AG H    ALA++L   K  I+M       +   V   +  G  VI      
Sbjct: 71  GSTVCAVSAGNHSQGVALAASLCNCKATIFMPENAPSAK---VKATQHYGGTVIQT---G 124

Query: 164 ATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRL 223
           AT  DA NE  +      +           P      +      IG E   QI + +   
Sbjct: 125 ATFDDAKNEMFKALEQHKDWIF-------VPPYNDREIIAGTGTIGLEIAQQIPKVQ--- 174

Query: 224 PDAVIACVGGGSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGM 282
              V+  +GGG    G+          V +IGV+          +         GI    
Sbjct: 175 --TVVVPIGGGGLISGIAYALKALKPKVRIIGVQMASCPATYKIYNQNKNKAIEGIRHET 232

Query: 283 KAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLH 342
             P+              + G+   + G  +  + +    + V +++DE  EA   L   
Sbjct: 233 LTPL--------------ADGIAVKTPGDLNLAIINDLVDEIVIVSEDEVAEAVALLAER 278

Query: 343 EGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
             +I     +  LA  L    +     +++   +SG G+  +  +   +  
Sbjct: 279 SKVISEGAGATPLAAVLSKKFKYQP-NEVICCVVSG-GNIPLRMLARCIDR 327


>UniRef50_Q3A4C8 Cysteine synthase n=3 Tax=Bacteria RepID=Q3A4C8_PELCD
          Length = 298

 Score =  183 bits (464), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 59/326 (18%), Positives = 102/326 (31%), Gaps = 52/326 (15%)

Query: 65  ITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE---IIAETGAGQHGVASAL 121
           ++  +   ++ K E L  GG+ K          AK+ GK      I E  +G  G++ A 
Sbjct: 18  LSKISTGNVFAKAEFLNPGGSIKDRVARNIIDSAKKEGKLTSGMTIIEATSGNTGISLAW 77

Query: 122 ASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSY 181
             A  G      M     E     +  +R  G E I   +    +   C +  ++     
Sbjct: 78  VGAQCGHHVVCVMPENVSE---ERMKIIRAFGGETISTPADENLIG--CLKKAKEIMQLE 132

Query: 182 ETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMF 241
              ++           P       +  G    AQI +      D  +A VG G    G+ 
Sbjct: 133 PGKYF----FVNQFSNPHNPETHYKQTG----AQIWDDLKGEIDIFVAGVGSGGTLQGVA 184

Query: 242 ADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSI 300
                    + +I VEP       G+   P  H   GI  G    +              
Sbjct: 185 KFLKEKNPAIKIIAVEPKNSATLLGKE--PGLHQIQGIGDGFIPEV-------------- 228

Query: 301 SAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALK 360
                          L+        +++D+EA++  + L   EG++    S   +  AL 
Sbjct: 229 ---------------LDLDLVDSVFTVSDEEAIDTTRKLSRQEGLLVGTSSGANVFAAL- 272

Query: 361 MMRENPDKEQLLVVNLSGRGDKDIFT 386
              +  +    +V  L  R ++   T
Sbjct: 273 ---QFDNGRNRVVTVLPDRAERYFST 295


>UniRef50_C5DI11 Cysteine synthase n=19 Tax=Saccharomyceta RepID=C5DI11_LACTC
          Length = 391

 Score =  183 bits (464), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 58/338 (17%), Positives = 112/338 (33%), Gaps = 33/338 (9%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE-----IIAETG 111
           T + K ++++  T   +Y K E    GG+ K    LG    A+R G        ++ E  
Sbjct: 51  TPVIKIKSLSKATGCEVYAKMELCNPGGSAKDRVALGIVRAAERQGLLRPGFPDVVFEGT 110

Query: 112 AGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHS----GSATLK 167
           +G  G++ A     LG +  I +       +      +  +GA++  V            
Sbjct: 111 SGSTGISIATICNALGYRAHISLPDDTSAEKL---ALLESLGAQINKVRPAGIVDPEQYV 167

Query: 168 DACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAV 227
           +A   A    + S + +H   G  A         R   +  G E   Q+        DA 
Sbjct: 168 NAAQRACNQLNQSGDGSH--RGVFADQFENDANWRVHYQGTGPEIYRQL----DGRIDAF 221

Query: 228 IACVGGGSNAIGMFADFINET--NVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAP 285
           IA  G G    G+      +    + ++  +P G G         +           +  
Sbjct: 222 IAGCGTGGTIAGVARFLKEKLGGRLRVVLADPQGSGFYNRVKFGVMYDRVEQEGTRRRHQ 281

Query: 286 MMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGI 345
           +    +G      + +     P               D   +TD +A+   K L +++G+
Sbjct: 282 VDTIVEGIGLNRITHNFSQGEP------------YIDDAERVTDGQAVRMAKFLSVNDGL 329

Query: 346 IPALESSHALAHALKMMRENPDKEQLLVV-NLSGRGDK 382
                ++     A+K+    P   +++++   SG    
Sbjct: 330 FIGSSTAINAVAAVKVAESLPPGSRIVIIACDSGSRHL 367


>UniRef50_B2UPE5 Pyridoxal-5'-phosphate-dependent protein beta subunit n=1
           Tax=Akkermansia muciniphila ATCC BAA-835
           RepID=B2UPE5_AKKM8
          Length = 538

 Score =  182 bits (463), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 72/367 (19%), Positives = 118/367 (32%), Gaps = 44/367 (11%)

Query: 34  SAQKDPEFQAQFNDLLKNY-AGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVL 92
           S   D   +       + Y  G PT L +      G    +Y KREDL    A+K     
Sbjct: 21  SILSDRLSEEILQARQRVYTVGEPTPLQRLNL--PGIKAPVYAKREDLGPIRAYKWRGAF 78

Query: 93  GQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLM 152
                  +  + + I    AG H    ALA+ +L     I+M     E +   V   R  
Sbjct: 79  NCMAALSQEARDKGIVAASAGNHAQGVALAARVLNCHATIFMPRSTPEVKQTEV---RRH 135

Query: 153 GAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIV-REFQRMIGEE 211
           G   + +        +    A           +         HPY  +V    Q  + +E
Sbjct: 136 GGRHVKIMLHGDCYDETAAAAHE---------YTETHGCTFVHPYDDLVTMAGQGTLADE 186

Query: 212 TKAQILEREGRLP-DAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGA 269
                    G  P D     +GGG  A  +         ++ +IGVE    GI+      
Sbjct: 187 VV-----MSGEGPFDRAYVAIGGGGLAASVACWLKKFWPHIKVIGVE----GIDQASMKT 237

Query: 270 PLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITD 329
            ++ GR      +                    G      G     L      ++V++T+
Sbjct: 238 SIEQGRRVNLDYVDVFC---------------DGTAVHIPGELTYPLCRELVDEFVTVTN 282

Query: 330 DEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDK-EQLLVVNLSGRGDKDIFTVH 388
           +E  +A + +     ++P    + +LA  LK       K E+   V +SG  + D   + 
Sbjct: 283 NEVCQAIRAMWESSRVVPEPSGAMSLAGFLKQWNRGEVKPEEKSFVVISGA-NMDFTHLT 341

Query: 389 DILKARG 395
            I +  G
Sbjct: 342 QIARQAG 348


>UniRef50_A6F8H1 Threonine dehydratase n=1 Tax=Moritella sp. PE36 RepID=A6F8H1_9GAMM
          Length = 505

 Score =  182 bits (463), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 73/357 (20%), Positives = 125/357 (35%), Gaps = 51/357 (14%)

Query: 25  LRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGG 84
           ++ +E  F      P F             +PT + +  N++  TN  +YLKREDL    
Sbjct: 3   IQIIESYFNKIVTSPVFD----------YLKPTPVDRLVNLSKQTNNDIYLKREDLQDIN 52

Query: 85  AHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSP 144
           + K      + +    +     +    AG H    A     LG    I M     + +  
Sbjct: 53  SFKIRGAYQKIISLPLIQLNRGVVAASAGNHAQGVAKVCKELGTTATIVMPDTTPKIK-- 110

Query: 145 NVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTI-VRE 203
            V  +R  GA V+             +EA R      ++        +  HP+  I V  
Sbjct: 111 -VDAVRSYGANVVLHGVN-------YDEAYRYAYNLADSR-----DLSLIHPFDDIEVIC 157

Query: 204 FQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINE-TNVGLIGVEPGGHGI 262
            Q  IG E  +Q+ +      D +   VGGG    G+         +  +I VEP     
Sbjct: 158 GQGTIGLEFASQVEQL-----DYLFVQVGGGGLLAGLTIAMNTLSPSTKIIAVEP----- 207

Query: 263 ETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRA 322
                      G   +   ++A ++   D       S S G+    +G     +      
Sbjct: 208 ----------EGAQTLGVSLRAKVISKLDSIC----SFSDGVAVGQIGKLPYEICKDAID 253

Query: 323 DYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGR 379
           D+++++ DE   A + +      I     +  LA A K ++++  K + + V LSG 
Sbjct: 254 DHMTVSKDEVCSAIQYIHEDTRAIAEGSGAVGLAGAYKYLKDHHIKGKKIGVILSGS 310


>UniRef50_D2VUI3 Predicted protein n=1 Tax=Naegleria gruberi RepID=D2VUI3_NAEGR
          Length = 485

 Score =  182 bits (463), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 57/372 (15%), Positives = 104/372 (27%), Gaps = 78/372 (20%)

Query: 36  QKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGT---------NTTLYLKREDLLHGGAH 86
               + +  F  +       PT L +   +T               ++LK E+    G+ 
Sbjct: 91  VSFYDIEEAFARI--KPLLPPTPLQESAVLTQEIFGQQKNVLHPRKVFLKYENKHMTGSF 148

Query: 87  KTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNV 146
           K    + +        +   +  + AG H                              V
Sbjct: 149 KERGAINKLAALDTEQRKRGVVASSAGNH--------------------------PLSKV 182

Query: 147 FRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQR 206
              +  GAEV+       ++ DA  EALR                  P      +   Q 
Sbjct: 183 AGTKRYGAEVVLF---GESVDDAYQEALRIKEAENR-------VLVHPF-NDDAIIAGQG 231

Query: 207 MIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETG 265
            +G E   Q         D ++  +GGG    G+          + + GV+         
Sbjct: 232 TLGLELLEQSP-----YIDTIVCPIGGGGLISGVAIACKTVNPKIKVYGVQTENVPSM-- 284

Query: 266 EHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYV 325
                                   +   +    +I+ G+    +G     +      D V
Sbjct: 285 -----------------VTAKKNRKSTTVPFHATIADGIAVRRIGDLTFPIIDQFVDDIV 327

Query: 326 SITDDEALEAFKTLCLHEGIIPALESSHALAHA----LKMMRENPDKEQLLVVNLSGRGD 381
           ++T+ E   A   L   E  +     +  +A      L+ + +       +   LSG G+
Sbjct: 328 TVTESEIAHAVLVLLEREKTLVEGAGATPVAALLSGKLEEVTKTSSGSHRVCCILSG-GN 386

Query: 382 KDIFTVHDILKA 393
            D+ TV DI+  
Sbjct: 387 MDVGTVRDIIDR 398


>UniRef50_Q22B57 Threonine dehydratase family protein n=2 Tax=cellular organisms
           RepID=Q22B57_TETTH
          Length = 481

 Score =  182 bits (462), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 64/368 (17%), Positives = 117/368 (31%), Gaps = 46/368 (12%)

Query: 27  QLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAH 86
           +L+          +    + D+      R T LT+   ++      ++LKREDL    + 
Sbjct: 61  ELKTDLSKLCPINKIYKAYKDIRS--TVRRTPLTQSLYLSEKYGANVFLKREDLQIVRSF 118

Query: 87  KTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNV 146
           K    L + +      K + +    AG H    A     +  K  I+M       +  +V
Sbjct: 119 KLRGALNKFVNLTTEEKAKGVVCASAGNHAQGVAYCCNYMKTKGTIFMPVNAPSIKLRSV 178

Query: 147 FRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQR 206
              +  G   I V     T  +    A +              T    +     V E Q 
Sbjct: 179 ---KSWGGPYIEVKLIGNTFDECFRAAKKYCEE-------TSSTFVHAYDDDK-VIEGQA 227

Query: 207 MIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETG 265
            I  E             D +  C+GGG    G+ + F +   +  ++G EP G      
Sbjct: 228 TIAVEILEDFQGTI----DYIFICIGGGGLCAGVGSYFKHMSPDTVIVGCEPEGCP---- 279

Query: 266 EHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSV---GPQHAYLNSTGRA 322
                             +  +  ++   E   SI+  +D  +V   G +   + S    
Sbjct: 280 ------------------SMKLAVQNNNPEPLKSINPFVDGAAVGIPGKRTHEIISNLMP 321

Query: 323 DYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDK 382
             + I +     A   +   E I+     + A+A       E   K  + +++ S   + 
Sbjct: 322 GVLLIPEGVVCSALLDIYNAESIVVEPAGALAIAGLNYYKEELKGKNVVCIISGS---NN 378

Query: 383 DIFTVHDI 390
           D+  + DI
Sbjct: 379 DLTRMTDI 386


>UniRef50_C6C043 Cysteine synthase n=5 Tax=Bacteria RepID=C6C043_DESAD
          Length = 764

 Score =  182 bits (462), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 61/330 (18%), Positives = 104/330 (31%), Gaps = 55/330 (16%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG---KTEIIAETGAG 113
           T L + + +    N  +  K E +  GG+ K          A++ G     +II E  +G
Sbjct: 13  TPLVEMRVLNPNKNVKILAKLEAMNPGGSIKDRAAGAMIRKAEKSGELTPDKIIIEATSG 72

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
             G+  A+A A+ G K  + M     E +      MR  GAE++      AT   A  +A
Sbjct: 73  NTGIGLAMACAVRGYKLMLIMPETASEERKM---IMRAYGAEIMLTPGHLAT-DGAIEQA 128

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
            R +    E            +     +       G+E   Q           V+AC+G 
Sbjct: 129 YRFYREEPEKY-----LLMDQYNNEASIDAHYEGTGQEIWDQ----TEGKVTHVVACLGT 179

Query: 234 GSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDG 292
               +G+         ++ +I VEP                                   
Sbjct: 180 TGTVMGITKRLKELNKDIQMIAVEPE---------------------------------- 205

Query: 293 QIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESS 352
                + I  GL            +       + + D++A E+ + L   EG+   + S 
Sbjct: 206 ---PGHKIQ-GLKNMQESYPPGIYDKQKLDRVIRVQDNDAFESCRRLAKEEGVFVGMSSG 261

Query: 353 HALAHALKMMRENPDKEQLLVVNLSGRGDK 382
            A+A A  +  E  D   + +    G    
Sbjct: 262 AAMAGAAAIASEIEDGLVVTIFPDGGERYL 291


>UniRef50_UPI0001978075 cysteine synthase n=1 Tax=Helicobacter cinaedi CCUG 18818
           RepID=UPI0001978075
          Length = 301

 Score =  182 bits (462), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 58/329 (17%), Positives = 104/329 (31%), Gaps = 54/329 (16%)

Query: 53  AGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK---TEIIAE 109
               T +   +         LY K E L    + K          A + GK     +I E
Sbjct: 10  IIGNTPILNLKEFAP----NLYGKCEFLNPSHSVKDRPAYAMIDEAMKQGKINKDTMIVE 65

Query: 110 TGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDA 169
             +G  G++ A+  A  GLK  I M              +   GA ++   + S  +K A
Sbjct: 66  CTSGNMGISLAMICASFGLKITITMPESM---SVERRKMISFFGANLVLTPA-SEGMKGA 121

Query: 170 CNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIA 229
            ++A ++   S                     +  +R    E             D  +A
Sbjct: 122 LDKA-KEILDSTPNVFMPS-----QFDNLDNKQMHKRTTALEIYESFEGEL----DYFVA 171

Query: 230 CVGGGSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQ 288
             G G    G+      +  ++ +IGVEP    + +       K              +Q
Sbjct: 172 GFGTGGTISGVGEVLKEKIPHIQIIGVEPSASPLLSQGQAGAHK--------------IQ 217

Query: 289 TEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPA 348
                                    + LN       V + ++ A++  + L    G++  
Sbjct: 218 GIGANFIP-----------------SILNRDVIDSIVCVENEVAIQTAQELGRV-GVMVG 259

Query: 349 LESSHALAHALKMMRENPDKEQLLVVNLS 377
           + S   +A A K+  ENP+K+ L ++N +
Sbjct: 260 ISSGANVAMARKIALENPNKKVLTMLNDT 288


>UniRef50_D1Y7A1 Pyridoxal-5'-phosphate-dependent protein beta subunit n=1
           Tax=Pyramidobacter piscolens W5455 RepID=D1Y7A1_9BACT
          Length = 382

 Score =  182 bits (462), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 59/351 (16%), Positives = 108/351 (30%), Gaps = 38/351 (10%)

Query: 34  SAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLG 93
           S  +   F     +  K  +     LT         +    LK +  +   + K      
Sbjct: 65  SIFRYRAFMPPLGENWKAVSLGEG-LTPVVRFDDDLS----LKMDYFMPTLSFKDRGAAV 119

Query: 94  QALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMG 153
                + +G    +A+  +G  G + A   A  G+ C I++           +  +R  G
Sbjct: 120 LVSHCRAIGVRS-VAQDSSGNAGNSVAAYCARAGIACEIFVPEGT---SPKKIDMIRAHG 175

Query: 154 AEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETK 213
           A    V        D C  A+R+         Y       P  Y     E  +    E  
Sbjct: 176 ARAHVVPGSRDHCADVCRAAVRE------RGLYYANHVYNPFFY-----EGTKTYLYEIY 224

Query: 214 AQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKH 273
            Q+    GR+P  +   VG G+  +G+          G++   P    +++      L+ 
Sbjct: 225 EQL----GRVPRNIFVPVGNGTLYLGVVKALEEFLAAGIVAAMPNVVLMQSENCAPLLEA 280

Query: 274 GRVGIYFGMKAPMMQTEDGQIEESYSISAGLDF--PSVGPQHAYLNSTGRADYVSITDDE 331
            R G           TE  +I+   +++ G+    P  G              V++ +D 
Sbjct: 281 WRSG----------DTEPARIDPRPTLAEGIAIGQPMRGEAILASVRKYDFKIVAVPEDA 330

Query: 332 ALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDK 382
            L   + L    GI     ++   A   +           ++  + G G K
Sbjct: 331 ILACRRELAAK-GIYCEHTTAANYAGYRRYCELYGRAPDSVI-PMCGAGLK 379


>UniRef50_Q3M387 L-threonine synthase n=107 Tax=cellular organisms
           RepID=Q3M387_ANAVT
          Length = 454

 Score =  182 bits (462), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 69/376 (18%), Positives = 126/376 (33%), Gaps = 29/376 (7%)

Query: 21  LMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTN-TTLYLKRED 79
           L     +++    S  +   F     D + +     T L +   +        LY+K + 
Sbjct: 74  LSVTREKIQAGPNSIWRYRPFLPVTTDNVIDVGTGMTPLVRSHRLARRLGLNKLYIKNDA 133

Query: 80  LL-HGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKD 138
           +     + K   V      A+ +G T  ++    G    ++A  +A  GL C +++ A  
Sbjct: 134 VNMPTLSFKDRVVSVALSRARELGFTT-VSCASTGNLANSTAAIAAHAGLDCCVFIPAD- 191

Query: 139 VERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYP 198
              ++  +    +    ++ V      +   C+E            H          PY 
Sbjct: 192 --LEAGKILGSLIYSPTLMAVKGNYDQVNRLCSEVA--------NTHGWGFVNINLRPYY 241

Query: 199 TIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPG 258
           +   E  + +G E   Q+      LPD V+A +  GS    ++  F     VGL+  +  
Sbjct: 242 S---EGSKTLGFEVAEQL---GWELPDHVVAPLASGSLFTKIYKGFQEFVEVGLVEGKKV 295

Query: 259 GHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNS 318
                  E  +P+          +K     T       + SI+ G     V        +
Sbjct: 296 RFSGAQAEGCSPIAQAFKEDRDFIKPVKPNTI------AKSIAIGNPADGVYAVDIAKKT 349

Query: 319 TGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENP-DKEQLLVVNLS 377
            G  +  S+ D E +E  K L   EGI         +A   K++     D ++  VV ++
Sbjct: 350 GGNIE--SVNDAEIIEGIKLLAETEGIFTETAGGTTVAVLKKLVEAGKIDPDETTVVYIT 407

Query: 378 GRGDKDIFTVHDILKA 393
           G G K    V   +  
Sbjct: 408 GNGLKTQEAVQGYVGE 423


>UniRef50_P71128 Cysteine synthase B n=12 Tax=Campylobacter RepID=CYSM_CAMJE
          Length = 299

 Score =  182 bits (461), Expect = 3e-44,   Method: Composition-based stats.
 Identities = 51/336 (15%), Positives = 99/336 (29%), Gaps = 54/336 (16%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK---TEIIAETGAG 113
           T +   +         ++ K E L    + K          A    K      I E  +G
Sbjct: 14  TPIIHLKKF----GINVFAKCEFLNPSHSIKDRAAFEMIKDALDSKKINQDTTIVEATSG 69

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
             G++ A+  A LGLK    M              + L GA +    +    +K A ++A
Sbjct: 70  NTGISLAMICADLGLKFIAVMPESM---SLERRKMITLFGARLELTPANLG-MKGAVDKA 125

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
             +   +   +              +     ++    E    +        D  +A  G 
Sbjct: 126 -NEILLNTPNSFM-----VSQFENISNKNAHRKNTALEILRDLDNEL----DIFVAGFGT 175

Query: 234 GSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDG 292
           G    G+          V ++GVEP    + +       K              +Q    
Sbjct: 176 GGTISGVGEILKEKLEKVHIVGVEPLNSPLLSKGEAGSHK--------------IQGIGA 221

Query: 293 QIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESS 352
                                A LN     + +++++++A+   K L    G++  + S 
Sbjct: 222 NFIP-----------------AILNKEVIDEVITVSNEDAINTAKELAKS-GLMVGISSG 263

Query: 353 HALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVH 388
             +  A  + ++ PDK  L ++N +           
Sbjct: 264 ANVFAASMLAKKFPDKRILTMLNDTAERYLSTDLFA 299


>UniRef50_UPI000180C4E2 PREDICTED: similar to Serine racemase n=1 Tax=Ciona intestinalis
           RepID=UPI000180C4E2
          Length = 321

 Score =  182 bits (461), Expect = 3e-44,   Method: Composition-based stats.
 Identities = 64/358 (17%), Positives = 110/358 (30%), Gaps = 55/358 (15%)

Query: 23  PALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLH 82
           P L  ++ A        E                T L  C++I       +++K E+   
Sbjct: 8   PTLDDIKAARERIVHHIE---------------KTPLISCRSINDACGRKIFMKAENFQK 52

Query: 83  GGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQ 142
            G+ K        L A      + +    +G HGVA A    +L +   + M        
Sbjct: 53  SGSFKVRGAFNAVLSALEKDGVKSLVTHSSGNHGVALAKVGRVLNIPVTVVMPKTAP--- 109

Query: 143 SPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVR 202
                     GAEVI      A  +  C E  R        A ++  +          V 
Sbjct: 110 PFKRKSATSFGAEVIECEPTHAERERKCEEVQR-----NTEAMFVSSSQ------DLRVI 158

Query: 203 EFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHG 261
             Q  +  E   +  +      DA++  VGGG    G+       + ++ + G EP    
Sbjct: 159 AGQGTVALEMLEKQPDL-----DAIVVPVGGGGLLSGVATAAKAIKPSIQIYGAEPEI-- 211

Query: 262 IETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGR 321
                    L+ G+                       +I+ GL   ++G     +     
Sbjct: 212 --ANSCYKSLRSGQRTTLQEY--------------PNTIADGLRT-NIGSITWPIIKQKV 254

Query: 322 ADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMR-ENPDKEQLLVVNLSG 378
            D + +T+DE   A   +     I+    S+ ALA      + +       + V L+G
Sbjct: 255 DDLILVTEDEIASAMALIWERAKIVVEPSSAVALAAVKSHSKAKGLAGISKVGVVLTG 312


>UniRef50_C5DGC1 KLTH0D04092p n=2 Tax=Saccharomycetales RepID=C5DGC1_LACTC
          Length = 493

 Score =  182 bits (461), Expect = 3e-44,   Method: Composition-based stats.
 Identities = 50/344 (14%), Positives = 107/344 (31%), Gaps = 45/344 (13%)

Query: 57  TALTKCQNITAGTNTT--LYLKREDLLHGGAHKTNQVLGQALLAKRMGK----TEIIAET 110
           T +     +         +Y K E    GG+ K          A++ G+       + E 
Sbjct: 17  TPMVHLTKLPKALGVKPQVYAKLELYNPGGSIKDRIAKSMIEDAEKSGRIHPSRTTLIEP 76

Query: 111 GAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDAC 170
            +G  G+  AL  A+ G +  I +  K    +   V  ++ +GAE+I   + +     A 
Sbjct: 77  TSGNTGIGLALMGAVKGYRTIITLPEKMSNEK---VSVLKALGAEIIRTPTAA-----AW 128

Query: 171 NEALRDWSGSYETAHYMLGTAA-GPHPYPTIVREFQRMIGEETKAQILEREG-RLPDAVI 228
           +        + +    +        +          +  G+E + Q+ +         V 
Sbjct: 129 DSPESHIGVAKKLEKEIPHAVILDQYNNMKNPEAHYQGTGKEIQGQLQQLGEYENLHGVF 188

Query: 229 ACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMM 287
           A  G G    G+          + +IG +P G  +   E     +              +
Sbjct: 189 AGAGTGGTISGISKYLKEQNPEIKIIGADPEGSILAQPESLNETEAAE---------YKV 239

Query: 288 QTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIP 347
           +                           L+      +    D ++    + L  +EG++ 
Sbjct: 240 EGIGYDFIP-----------------KVLDRGLVDTWYKTNDIDSFRYARQLIANEGLLV 282

Query: 348 ALESSHALAHALKMMRENPD--KEQLLVVNLSGRGDKDIFTVHD 389
              S  A +  +K  +++P+  ++ +LV+ L       +    D
Sbjct: 283 GGSSGSAFSAMMKYCKDHPELTEKDVLVIILPDSIRSYLTKFAD 326


>UniRef50_Q88I11 Threonine dehydratase family protein n=43 Tax=cellular organisms
           RepID=Q88I11_PSEPK
          Length = 350

 Score =  181 bits (460), Expect = 4e-44,   Method: Composition-based stats.
 Identities = 71/346 (20%), Positives = 113/346 (32%), Gaps = 44/346 (12%)

Query: 38  DPEFQAQFNDLLKN------YAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQV 91
           D +F    +  +++       A   T L     ++A T   + LK E L H G+ K    
Sbjct: 29  DAQFLDTLHQNIQDAHAALRPAVSITPLLHSPRLSALTGCEVLLKCEHLQHTGSFKFRGA 88

Query: 92  LGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRL 151
             +  L     + + +    +G HG A ALA  + G+  ++Y         +     MR 
Sbjct: 89  SNKMRLLPAEARKQGVIAASSGNHGQALALAGKMAGVPVKVY---TTTGASAYKTEAMRA 145

Query: 152 MGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEE 211
           +GAEV+ + +   +   A  EA R             G           V   Q  IG E
Sbjct: 146 LGAEVVCLPTDPLS---AELEAARQAKAQ--------GVPFVSPYNDLQVIAGQGTIGME 194

Query: 212 TKAQILEREGRLPDAVIACVGGGSNAIGMFADFI-NETNVGLIGVEPGGHGIETGEHGAP 270
              Q  +      DAV   VGGG    G+ A     +    +IG  P             
Sbjct: 195 LLEQAPDL-----DAVFVAVGGGGMISGIGAALRVLKPGTEIIGCWPANDPTLQ----QS 245

Query: 271 LKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDD 330
           LK G   I        +        E  SI               L      D V +++D
Sbjct: 246 LKAGE--IIELDACETLSDGTAGGVEPGSI------------TFPLCQALLTDTVLVSED 291

Query: 331 EALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNL 376
           E   A + +   E  I    ++ A+A   ++      K   +++  
Sbjct: 292 EIRCAMRDIASSERWIIEGAAAVAVAGMQRLAERYQGKRVAVILCG 337


>UniRef50_A6VNW0 Pyridoxal-5'-phosphate-dependent protein beta subunit n=8
           Tax=Proteobacteria RepID=A6VNW0_ACTSZ
          Length = 364

 Score =  181 bits (460), Expect = 4e-44,   Method: Composition-based stats.
 Identities = 58/360 (16%), Positives = 114/360 (31%), Gaps = 38/360 (10%)

Query: 25  LRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGG 84
           L  ++    S  +  +F A  ++  +  +     +T            + LK +  +   
Sbjct: 38  LNDIDRHEWSLFRYRKFIALQDESWRGISLGEG-MTPIVRFDD----NVLLKMDYFMPTL 92

Query: 85  AHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSP 144
           + K           K +G   ++ +  +G  G + A   A  G++C I++          
Sbjct: 93  SFKDRGAAVLISHCKAIGVDSVVQD-SSGNAGNSVAAYCAKAGIQCEIFVPEGT---SPK 148

Query: 145 NVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREF 204
            +  +   GA+   +        D C   +           Y       P  Y     E 
Sbjct: 149 KINMIEAHGAKANVIAGSRDHCADVCRAKVE------NEGIYYANHVYNPFFY-----EG 197

Query: 205 QRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIET 264
            +    ET  Q+    GR+P  ++  VG G+  IG+     +    G I   P    +++
Sbjct: 198 TKTYIYETFEQL----GRIPKHIVVPVGNGTLFIGVIKGLEHLLASGAINEMPTIIALQS 253

Query: 265 GEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDF--PSVGPQHAYLNSTGRA 322
                 L+    G          Q     +E   +I+ G+    P    +          
Sbjct: 254 EHCDPLLQAVEKG----------QKFAENVEVKPTIAEGIAIGQPMRAAEILTYAEKYPV 303

Query: 323 DYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDK 382
            +V   +D+ L A   L    G+     ++   A  L+   E     +  ++ + G G K
Sbjct: 304 RFVHAPEDKILAARDILAKK-GVYCEHTTAANYAAYLRYC-ELYGTAEDCLITMCGAGLK 361


>UniRef50_D2B021 Pyridoxal-5'-phosphate-dependent protein beta subunit n=10
           Tax=Bacteria RepID=D2B021_STRRD
          Length = 392

 Score =  181 bits (460), Expect = 4e-44,   Method: Composition-based stats.
 Identities = 70/382 (18%), Positives = 122/382 (31%), Gaps = 39/382 (10%)

Query: 17  VPQILMPAL----RQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTT 72
            P  L P       Q++ +  S  +             +     T +             
Sbjct: 35  TPLALSPMPGLTPDQIDTSERSLWRYHAAIPVSPRHRVSLGEGFTPMLPL----DWNGLR 90

Query: 73  LYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRI 132
           ++ K E      + K   +       +  G+T ++ E  +G  G + A  +A  G+  +I
Sbjct: 91  VHFKLEWFNPTSSFKDRGITVMISHLRGQGETHVL-EDSSGNGGSSVAAYAAAAGIHAKI 149

Query: 133 YMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAA 192
            + A     +   + + R  GA++  V      + D   EA+R                 
Sbjct: 150 IVPAATSAAK---ILQARAYGAQIELVEGTREQVSD---EAIRQSEQI----------PY 193

Query: 193 GPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGL 252
             H +     +  + I  E    +     R PD ++   G GSN +G    F        
Sbjct: 194 ASHNWHPFFLQGTKTIAYEMWESL---GFRAPDNIVLVAGAGSNILGCDIAFSELLEARQ 250

Query: 253 IGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQ 312
           I   P    +   EH A +     GI    + P + T    I E  SI+  +      P+
Sbjct: 251 IDRRPKLL-VGQPEHWATIADAVNGIDPRSRGPRVPT----IAEGASIANPVRL----PE 301

Query: 313 HAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALK-MMRENPDKEQL 371
                       V++T+D+   A + L    G+     SS A A     M       ++ 
Sbjct: 302 TVEAIRRSGGAAVAVTEDQIRTAVRKLASR-GLYAEPTSSVAAAALDHFMADGAIGPDET 360

Query: 372 LVVNLSGRGDKDIFTVHDILKA 393
            VV L+G G K    +  +   
Sbjct: 361 TVVILTGAGLKSAEKMAAVFDT 382


>UniRef50_Q54CN7 Cysteine synthase n=1 Tax=Dictyostelium discoideum RepID=CYSK_DICDI
          Length = 378

 Score =  181 bits (459), Expect = 4e-44,   Method: Composition-based stats.
 Identities = 56/328 (17%), Positives = 107/328 (32%), Gaps = 32/328 (9%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG---KTEIIAETGAG 113
           T L + ++++  T   +Y K E +  GG+ K        L  ++ G   K   I E  AG
Sbjct: 49  TPLIRIKSLSEATGCEIYGKAEFMNPGGSPKDRVAREIILDGEKKGLLKKGSTIVEATAG 108

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
             G++  +     G   ++++     + +   V  + ++GAE   V        +     
Sbjct: 109 STGISLTMLGKSRGYNVQLFIPDNVSKEK---VDLLEMLGAETKIVPIVGMNNANHFMHC 165

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
                   + A Y     A      +          +E   Q         D  +A  G 
Sbjct: 166 AYQRCLGDDMAFY-----ANQFDNLSNFNAHYNGTAKEIWEQTK----GDVDGFVAAAGT 216

Query: 234 GSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDG 292
           G    G+ +       N+    ++P G G+ +  +   + H +  +      P    E  
Sbjct: 217 GGTVAGISSYLKEVNPNIQNWLIDPPGSGLYSLVNTGVIFHPKDRLVVEKLGPRSFYEG- 275

Query: 293 QIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESS 352
                           V  +    N          T++E ++    L  H+G+     S+
Sbjct: 276 --------------VGVNKKTENFNKASLNGAFRGTEEEGVDMAHYLLKHDGLFLGGSSA 321

Query: 353 HALAHALKMMRE-NPDKEQLLVVNLSGR 379
                A+K+ R+  P K  + V+  SG 
Sbjct: 322 LNCVGAVKLARKLGPGKTIVTVLCDSGH 349


>UniRef50_Q7MYV0 Cysteine synthase n=1 Tax=Photorhabdus luminescens subsp. laumondii
           RepID=Q7MYV0_PHOLL
          Length = 342

 Score =  181 bits (459), Expect = 5e-44,   Method: Composition-based stats.
 Identities = 60/330 (18%), Positives = 108/330 (32%), Gaps = 53/330 (16%)

Query: 70  NTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE---IIAETGAGQHGVASALASALL 126
              ++LK E++  GG+ K    +     A+  G+     ++ E  +G   +  A+A A+ 
Sbjct: 26  GINVFLKMENINPGGSIKDRIAVAMLERAEAQGELRPGMVVIEPSSGNTAIGLAMACAVK 85

Query: 127 GLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVH---SGSATLKDACNEALRDWSGSYET 183
           G +    +       +     +++  GAE+I +    +G  T+K   +   ++    Y  
Sbjct: 86  GYRFIAVLDRMVPAAK---RDKIKAFGAEIIFLPEFEAGKDTVKYRID-LTKEIIKVYPN 141

Query: 184 AHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFAD 243
           A   +              E  R  G E         G    A  A  G      G+   
Sbjct: 142 AFSPM-----QFENQVNPDEHYRSTGRELYE----IFGNNLTACFATAGSCGTLTGISRY 192

Query: 244 FIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISA 302
               +  V + GVEP G  I  GE G  L  G                            
Sbjct: 193 LKEKDPQVRIYGVEPVGSIIFGGEPGKYLVQG---------------------------- 224

Query: 303 GLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHAL-KM 361
                 +    + L+ T     + + D +A    + L  +EGI+       A++ AL ++
Sbjct: 225 ----AGLAFIPSILDRTNIDITLKVADIDAFRVARKLARNEGILIGGTGGCAVSAALNRL 280

Query: 362 MRENPDKEQLLVVNLSGRGDKDIFTVHDIL 391
               P    ++++  SG    D       L
Sbjct: 281 DDFKPGDNIVVIIPDSGERYIDTIYNDAWL 310


>UniRef50_C0D8B2 Putative uncharacterized protein n=1 Tax=Clostridium asparagiforme
           DSM 15981 RepID=C0D8B2_9CLOT
          Length = 321

 Score =  181 bits (459), Expect = 5e-44,   Method: Composition-based stats.
 Identities = 55/351 (15%), Positives = 110/351 (31%), Gaps = 43/351 (12%)

Query: 44  QFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK 103
           +    ++NY  + T L      +  T + ++ K E+L   GA+K    +   L       
Sbjct: 11  EAYGRIRNYV-QKTPLIYSPETSERTGSEVWFKMENLQPIGAYKLRGAMNNILGMSEEDL 69

Query: 104 TEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGS 163
              +    AG H  A A A+ L G+   + +       +     +    GA ++      
Sbjct: 70  KCGVVAASAGNHSQAVAYAAKLKGVSAVVCVPESTPMNKRYGAIK---HGARLVVYGPNY 126

Query: 164 ATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRL 223
              ++  +E   +    +  A+    T              Q  +  E+       E   
Sbjct: 127 EDAENRAHEIEAEEGRKFVHAYESNET-----------IAGQGTVAIESL-----LEKGD 170

Query: 224 PDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGM 282
            DA++   GGG    G+         ++ + G              AP            
Sbjct: 171 FDAILVPTGGGGLLCGVAIAAKAMNPDIKVYG--------LQTNTSAPWDKSFHERKLNN 222

Query: 283 KAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLH 342
             P +           + + GL+     P    L  T   D   + ++   E  K +   
Sbjct: 223 DCPFL----------PTCADGLEGAITWPNV-ELALTCVDDIFVVDEERTREGIKWMAQK 271

Query: 343 EGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
              +    S+  LA   +  +E   K+  ++  ++G G+ D+    +I + 
Sbjct: 272 HHYMIEGASATCLAALFEDHQELKGKK--VLCIITG-GNIDLDKFCEICEK 319


>UniRef50_D1X751 Pyridoxal-5'-phosphate-dependent protein beta subunit n=6
           Tax=Streptomyces RepID=D1X751_9ACTO
          Length = 376

 Score =  180 bits (458), Expect = 5e-44,   Method: Composition-based stats.
 Identities = 74/370 (20%), Positives = 126/370 (34%), Gaps = 38/370 (10%)

Query: 16  YVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYL 75
           + P+  + A   L     S  +  EF       +    GR T L    +       T+  
Sbjct: 37  FAPERGV-APNALSGRVDSLWRYEEFLPLAAPPISLGEGR-TPLVPLTD-------TVSA 87

Query: 76  KREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMG 135
           K + L+   + K    +  A LA+R+G   ++A+   G  G + A   A  GL C +++ 
Sbjct: 88  KLDYLMPTLSFKDRGAVMLAELARRLGPDRVVAD-STGNAGTSVAAYCARAGLPCTVFVP 146

Query: 136 AKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPH 195
                       ++R  GA ++ V  G               + +   A    G     H
Sbjct: 147 EGT---SPKKTEQIRAHGAHLVTVPGGR-----------EATALAARAAADGPGVFYASH 192

Query: 196 PYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGV 255
            +        +    E    +    GRLPDA+   VG G+  +G          +GLI  
Sbjct: 193 VFNPYFLHGTKTYVYELWEDL---GGRLPDALAVPVGNGTLLLGAALAVAELHALGLIAT 249

Query: 256 EPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGL---DFPSVGPQ 312
            P    ++           R G       P     D     S +++ G+     P     
Sbjct: 250 RPRLIAVQAEAVSPLAGAFRAGADD---LPPADPSDPAAVVSPTLAEGIAIPRPPRARQI 306

Query: 313 HAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLL 372
            A + ++G   ++++++D   EA + L    G      +  A   A++   E       L
Sbjct: 307 LAAVRASG-GTFLTVSEDHVREAQRDLAAR-GFYVE-TTGVACWAAVREGGEAVRGS--L 361

Query: 373 VVNLSGRGDK 382
           VV L G G K
Sbjct: 362 VVPLCGAGLK 371


>UniRef50_Q2YUE8 Threonine dehydratase biosynthetic n=181 Tax=Bacteria
           RepID=THD1_STAAB
          Length = 422

 Score =  180 bits (458), Expect = 5e-44,   Method: Composition-based stats.
 Identities = 61/360 (16%), Positives = 107/360 (29%), Gaps = 36/360 (10%)

Query: 35  AQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQ 94
                +    F  L      + T L     ++   +  +YLKREDL    + K       
Sbjct: 6   TVSTKDIDEAFLRL--KDIVKETPLQLDHYLSQKYDCKVYLKREDLQWVRSFKLRGAYNA 63

Query: 95  ALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGA 154
             +     K++ I    AG H       +  L L   I+M      ++   V +++  G 
Sbjct: 64  ISVLSDEAKSKGITCASAGNHAQGVVYTAKKLNLNAVIFMPVTTPLQK---VNQVKFFGN 120

Query: 155 EVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKA 214
             + V     T      EAL   S               P          Q  + +E   
Sbjct: 121 SNVEVVLTGDTFDHCLAEALTYTSEHQMN-------FIDPFNNV-HTISGQGTLAKEMLE 172

Query: 215 QILEREGRLPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKH 273
           Q         D + A +GGG    G+   F +   N  +IGVEP G              
Sbjct: 173 QSKSDNVNF-DYLFAAIGGGGLISGISTYFKSYSPNTKIIGVEPSGASSMYESV------ 225

Query: 274 GRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEAL 333
                       ++  +   +        G     VG     +      +YV + +    
Sbjct: 226 ------------VVNNQVITLPNIDKFVDGASVARVGDITFEIAKKNVDNYVQVDEGAVC 273

Query: 334 EAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
                +   + I+     + +++           K   +V  +SG G+ DI  + +I + 
Sbjct: 274 STILDMYSKQAIVAEPAGALSVSALENYKDHIKGK--TVVCVISG-GNNDINRMKEIEER 330


>UniRef50_D0L0K6 Threonine synthase n=20 Tax=Gammaproteobacteria RepID=D0L0K6_HALNC
          Length = 395

 Score =  180 bits (458), Expect = 5e-44,   Method: Composition-based stats.
 Identities = 60/338 (17%), Positives = 112/338 (33%), Gaps = 27/338 (7%)

Query: 57  TALTKCQNITAGTNT--TLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQ 114
           T L +  NI         +Y+K E L   G+ K   +      A   G   +I     G 
Sbjct: 42  TPLIRLNNIPRVLGCSLDIYVKYEGLNPTGSFKDRGMTMAVTKAVEAGSKAVICA-STGN 100

Query: 115 HGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEAL 174
              ++A  +A  G+   + +    +         M   GA  + +           ++ +
Sbjct: 101 TSASAAAYAARAGITAFVLIPDGKIAMGKLAQAMM--YGATTLQIRGN-------FDDGM 151

Query: 175 RDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGG 234
           R      + A   +  +  P        + Q+    E   ++    GR PD     VG  
Sbjct: 152 RLVKEVADHAPVTIVNSVNPFR-----LQGQKTAAFEIIEEL----GRAPDFHCLPVGNA 202

Query: 235 SNAIGMFADFINETNVG---LIGVEP--GGHGIETGEHGAPLKHGRVGIYFGMKAPMMQT 289
            N    +  +   +      L        G+           +   +G      AP ++ 
Sbjct: 203 GNITAHWIGYCESSASHGDNLTESCAFCDGNCAFVKGAACTNRPKMIGYQASGSAPFIRG 262

Query: 290 EDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPAL 349
                 E+ + +  +  P    +   + S     +  +TD E L A + L +HEGI    
Sbjct: 263 AMVDHPETLATAIRIGHPQSWDRAWKVMSESGGWFAEVTDTEILAAQRMLTMHEGIFCEP 322

Query: 350 ESSHALAHALKMMRENP-DKEQLLVVNLSGRGDKDIFT 386
            S+ +LA  +  ++     +   +V+ L+G G KD  T
Sbjct: 323 ASAASLAGLINDVKAGKIPEGSSVVLTLTGNGLKDPDT 360


>UniRef50_C3WXN8 Cysteine synthase n=12 Tax=Fusobacterium RepID=C3WXN8_9FUSO
          Length = 316

 Score =  180 bits (458), Expect = 6e-44,   Method: Composition-based stats.
 Identities = 63/338 (18%), Positives = 111/338 (32%), Gaps = 48/338 (14%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG---KTEIIAETGAG 113
           T L K  NI       +Y+K E    G + K    L      ++ G   K  +I E  +G
Sbjct: 23  TPLVKINNI-DTFGNEIYIKLEGSNPGRSTKDRIALKMIEEGEKAGLIDKDTVIMEATSG 81

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
             G+  A+  A+   K +I M           +  MR  G EVI       +L       
Sbjct: 82  NTGIGLAMICAVKNYKLKIVMPDTM---SVERIQLMRAYGTEVILTDG---SLGMKACLE 135

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
             +     E  +++              +       EE    +        D  I   G 
Sbjct: 136 KLEELKKKEKKYFIP----DQFTNVNNPKAHYETTAEEILKDL----NNKVDVFICGTGT 187

Query: 234 GSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDG 292
           G +  G          N+    VEP    + +  +  P K   +G+  G    +      
Sbjct: 188 GGSFSGTAKKLKERLANIKTFPVEPASSPLLSKGYIGPHKIQGMGMSIGGIPAVYDG--- 244

Query: 293 QIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESS 352
                 S++ G+                    ++  DD+A +  + L   EGI+  + + 
Sbjct: 245 ------SLADGI--------------------LTCEDDDAFKMMRELSFKEGILAGISTG 278

Query: 353 HALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDI 390
             L  AL   +EN +K   +V+  +  G+K +  + ++
Sbjct: 279 ATLKAALDYSKENANKNLKIVILSTDSGEKYLSNICEL 316


>UniRef50_A7RTQ8 Predicted protein n=2 Tax=Nematostella vectensis RepID=A7RTQ8_NEMVE
          Length = 424

 Score =  180 bits (458), Expect = 6e-44,   Method: Composition-based stats.
 Identities = 63/349 (18%), Positives = 104/349 (29%), Gaps = 38/349 (10%)

Query: 46  NDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE 105
                      TA  K    T   +  +++KRE L   G+ K        L      K  
Sbjct: 22  AAYRIRNGIEKTACEKLAPFTEIEDYDVFVKREYLQPTGSFKVRGARNALLTLTPEQKGR 81

Query: 106 IIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSAT 165
            +  T AG HG+A A     LG+   + +           V       A           
Sbjct: 82  GVITTSAGNHGLALAQQGDELGIPVMVLLPE---NVSPLKVKLCNRYNAT---TKLAGRN 135

Query: 166 LKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPD 225
             +  N A++  S       Y+           T V   Q  +G E   Q+ +      D
Sbjct: 136 ATEVRNMAIKFESEGGCGPIYIDENE------NTHVISGQGTMGLEIVDQVED-----VD 184

Query: 226 AVIACVGGGSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKA 284
           A+I  VGGG    G+         ++ +IGVE            A           G   
Sbjct: 185 AIIVPVGGGGLLAGISVAVKTLYPDIQIIGVEAAACPSFQAAMSA-----------GKPV 233

Query: 285 PMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEG 344
            +       + E   ++  +    +      L         ++ ++    A   L   E 
Sbjct: 234 KVKAEMWLTLAEGEYLALMITRVQLSHTPCPLC-------FAVREEHIALAVLRLLEKER 286

Query: 345 IIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
           II     +  LA  +        K + +VV L G G+ +  T+   ++ 
Sbjct: 287 IIIEGSGAAGLAALIGGYLP-ELKGKRVVVPLCG-GNIESTTLGRAIER 333


>UniRef50_C5CDJ9 Pyridoxal-5'-phosphate-dependent protein beta subunit n=33 Tax=root
           RepID=C5CDJ9_KOSOT
          Length = 475

 Score =  180 bits (458), Expect = 6e-44,   Method: Composition-based stats.
 Identities = 66/369 (17%), Positives = 113/369 (30%), Gaps = 53/369 (14%)

Query: 25  LRQLEEAFVSAQKDPEF-QAQFNDLLKNYAGRPTALTKCQNITAGT--------NTTLYL 75
           +  +   +     +          +        T L + +NIT              +++
Sbjct: 30  ISDIAFDYERMMNEVALDIDTVRKIQLETGVGNTNLIELKNITKLVRYISEPGKGARIFV 89

Query: 76  KREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMG 135
           K E     G+ K  +      +AK++G   +IA T  G +G + A  +A  GLKC I   
Sbjct: 90  KDEASNPSGSFKDRRASVSVYMAKKLGYEGVIAATS-GNYGASVASQAAKRGLKCIIVQE 148

Query: 136 AKDVE-----RQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGT 190
             D                   GAEV+ +  G         E    +    E   Y   +
Sbjct: 149 TYDSNGIGQPEILEKGRACETYGAEVVQLTVGP--------ELFYYFLVLLEETGYFNAS 200

Query: 191 AAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFIN--ET 248
              P+            +G E   Q  E+ G  PD V+    GG N  G     +     
Sbjct: 201 LYTPYG-----IAGVETLGYEIALQCREQIGCDPDYVVVTHAGGGNLTGTARGLLKAGAK 255

Query: 249 NVGLIGVEPGGHGIETGE----HGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGL 304
           N  ++      HG+        +      G  G          +++              
Sbjct: 256 NTKIVAASVDLHGLHMASDRDFNRKSFTTGHTGFGIPFAVYPDRSDV------------- 302

Query: 305 DFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRE 364
                 P++A         Y+ +T  E     + L   EG+      + +LA A+ + RE
Sbjct: 303 ------PKNAARALRYMDRYLLVTQGEVFYVTEMLARLEGMQRGPAGNTSLAAAISLARE 356

Query: 365 NPDKEQLLV 373
            P    ++V
Sbjct: 357 LPKDNIVVV 365


>UniRef50_D1CAE1 Pyridoxal-5'-phosphate-dependent protein beta subunit n=1
           Tax=Sphaerobacter thermophilus DSM 20745
           RepID=D1CAE1_SPHTD
          Length = 322

 Score =  180 bits (458), Expect = 6e-44,   Method: Composition-based stats.
 Identities = 73/350 (20%), Positives = 115/350 (32%), Gaps = 43/350 (12%)

Query: 45  FNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKT 104
              +L     R T L     I       +Y K E+L   G+ K   VL +        + 
Sbjct: 10  ARRVLAGRIHR-TPLIGSTEIGRRVGAPVYFKLENLQKTGSFKVRGVLNKIAALGPEERA 68

Query: 105 EIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSA 164
             +    AG H  A A A+   G+   + M A     +   V   +  GA V+       
Sbjct: 69  RGLLAASAGNHAQALAWAATAEGVASTVVMPADAPRTK---VQATQQYGATVVI------ 119

Query: 165 TLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLP 224
                  + ++ +S + E       T   P   P +V   Q  +G E    + E      
Sbjct: 120 -----EQDRMKLFSRADELTKERGLTFVPPFDDP-LVIAGQGTVGLEILEDLPEVG---- 169

Query: 225 DAVIACVGGGSNAIGMFADFI-NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMK 283
             V+  +GGG    G+         N  +IGVEP G         A        I     
Sbjct: 170 -TVVVPIGGGGLIAGVAVAIKGQRPNAKIIGVEPEGAPKMWRARQAGHTVKLDRID---- 224

Query: 284 APMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHE 343
                          +I+ GL  P  G     L      D V ++DDE  +A   L    
Sbjct: 225 ---------------TIADGLAAPFAGELTFSLVQRYVDDLVLVSDDEIRQAMFLLLERC 269

Query: 344 GIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
            ++     + ALA  L         +  +V  +SG G+ D+ ++  +L+ 
Sbjct: 270 KVLAEPAGAAALAALLTGKASVAP-DAPVVAIVSG-GNTDVASLSTLLQG 317


>UniRef50_C5C994 L-threonine ammonia-lyase n=59 Tax=Actinobacteria (class)
           RepID=C5C994_MICLC
          Length = 443

 Score =  180 bits (457), Expect = 7e-44,   Method: Composition-based stats.
 Identities = 74/382 (19%), Positives = 130/382 (34%), Gaps = 50/382 (13%)

Query: 13  GGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTT 72
           GG   P  L   L ++E A  + +   E                + L   + ++    T 
Sbjct: 26  GGAPTPAELPVTLGEIERARETLRGIAE---------------RSPLQHSRALSRAVGTD 70

Query: 73  LYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRI 132
           ++LK E+L   G+ K      +        +   +    AG H    ALA+A LG++ RI
Sbjct: 71  VHLKCENLQRAGSFKVRGAYVRMAQLSEEERGRGVVAASAGNHAQGVALAAAKLGIRARI 130

Query: 133 YMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAA 192
           +M         P +   R  GAEV+      +T+ ++  EA R  + +            
Sbjct: 131 FMPHGVA---LPKLQATRDHGAEVVL---HGSTVDESLAEAQRWATETDA-------VFI 177

Query: 193 GPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGL 252
            P   P  V   Q  +G E    + + +  +       +  G+      A       V +
Sbjct: 178 PPFDDPA-VIAGQGTVGLEILDVLPDVDTVIMGIGGGGLIAGTAVALKEAARRRGRTVRV 236

Query: 253 IGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQ 312
           IGV+        G     L+ GRV +   +                +I+ G+     G  
Sbjct: 237 IGVQAATAAAFPG----SLEEGRVQVLESV---------------STIADGIAVGRPGAL 277

Query: 313 HAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMM-RENPDKEQL 371
              + +      V++TDDE   A   L     ++     +  +A  L     +   +   
Sbjct: 278 PLRIAAELVDAVVTVTDDEIAAALVHLLERSKLVVEPAGAVGVAALLAGRTADLGFELGT 337

Query: 372 LVVNLSGRGDKDIFTVHDILKA 393
             V LSG G+ D   +   ++A
Sbjct: 338 TAVILSG-GNIDPMLMLKSIQA 358


>UniRef50_B6VLL1 Cysteine synthase n=1 Tax=Photorhabdus asymbiotica subsp.
           asymbiotica ATCC 43949 RepID=B6VLL1_PHOAA
          Length = 348

 Score =  180 bits (457), Expect = 8e-44,   Method: Composition-based stats.
 Identities = 58/334 (17%), Positives = 106/334 (31%), Gaps = 53/334 (15%)

Query: 70  NTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE---IIAETGAGQHGVASALASALL 126
              ++LK E++   G+ K    +     A+  G+     ++ E  +G   +  A+A A+ 
Sbjct: 32  GVNIFLKMENINPSGSIKDRIAVAMLEKAEAQGELRPGMVVVEPSSGNTAIGLAMACAVK 91

Query: 127 GLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVH---SGSATLKDACNEALRDWSGSYET 183
           G +    +       +     ++R  GAE+I +    +G+ T+K   +   ++   +Y  
Sbjct: 92  GYRFIAVLDRMVPAAK---RDKIRAFGAEIIFLPEFEAGTDTVKYRID-LTKEIIKAYPN 147

Query: 184 AHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFAD 243
           A   +              E     G E         G    A  A  G      G+   
Sbjct: 148 AFSPM-----QFENQINPDEHYHSTGRELYE----TFGDNLTACFATAGSCGTLTGISRY 198

Query: 244 FIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISA 302
                  V + GVEP G  I  GE G  L  G                            
Sbjct: 199 LKEKNPWVRIYGVEPVGSVIFGGEPGKYLVQG---------------------------- 230

Query: 303 GLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMM 362
                 +    + L+ +     + ITD +A    + L   EGI+     + ++   L  +
Sbjct: 231 ----AGLTFVPSILDLSNIDITLKITDIDAFRMARKLARDEGILLGGTGACSVCAVLDRL 286

Query: 363 RENPDKEQLLVVN-LSGRGDKDIFTVHDILKARG 395
            +    + ++V+   SG    D       L    
Sbjct: 287 DDFKPGDNIVVIIPDSGERYIDTIYNDAWLSENN 320


>UniRef50_Q9YCN5 Cystathionine beta-synthase n=1 Tax=Aeropyrum pernix
           RepID=Q9YCN5_AERPE
          Length = 389

 Score =  180 bits (457), Expect = 8e-44,   Method: Composition-based stats.
 Identities = 71/385 (18%), Positives = 119/385 (30%), Gaps = 74/385 (19%)

Query: 57  TALTKC---QNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG---KTEIIAET 110
           T L +    +         LY K E    GG+ K    L   + A+  G   +  +I E 
Sbjct: 20  TPLLRLGRVERFFRLEGVELYGKLEMFNPGGSVKDRIGLYMLMDARSRGLVEEGAVIIEP 79

Query: 111 GAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIP----VHSGSATL 166
            AG  GV  ALA+   G +    M +K    +      +R  GA VI     V   S   
Sbjct: 80  TAGNTGVGLALAAIHYGFRLVAVMPSKMSVEKE---LILRAYGAYVIRTPTAVPPESPLS 136

Query: 167 KDACNEALRDWS-------------------------GSYETAHYMLGTAAGP------- 194
                EA+R+                              E    +L  +  P       
Sbjct: 137 YYRVAEAVRNLLWMIGGRPGGGEVRKVVEKVQTLVREERVEDLRSILEASVEPTPYAYIP 196

Query: 195 --HPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFIN-ETNVG 251
             +  P   R  +   G E   Q     G   D V A +G      G+       + +V 
Sbjct: 197 NQYSNPANPRAHEETTGREIWMQ----TGGRVDVVYAGMGTRGTITGVARYLKRAKPSVR 252

Query: 252 LIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGP 311
           ++GV+P G      + G              +   ++        S    + +D      
Sbjct: 253 IVGVDPEGSIYSLVKKGMSPHEA----AKHARPYKVEGIGEDFIPSTIDLSLVD------ 302

Query: 312 QHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQ- 370
                      + V +TD +A    + L   EG++    S  AL  A+K ++    +   
Sbjct: 303 -----------EVVVVTDQQAFSMARMLARLEGVLAGGSSGAALYAAVKHIKTRRVRGVA 351

Query: 371 LLVVNLSGRGDKDIFTVHDILKARG 395
           ++++  +GR   +       +   G
Sbjct: 352 VVILPDTGRNYINKLYNDRWMGENG 376


>UniRef50_A4JPA1 L-threonine ammonia-lyase n=4 Tax=cellular organisms
           RepID=A4JPA1_BURVG
          Length = 507

 Score =  180 bits (456), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 70/352 (19%), Positives = 107/352 (30%), Gaps = 41/352 (11%)

Query: 38  DPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALL 97
           D  +     +         T L     ++    + + LKRED+    + K          
Sbjct: 4   DFNYLTSILNAPVYDVAVKTPLESLSRLSERLGSRVLLKREDMQPSFSFKVRGAYTLMAR 63

Query: 98  AKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVI 157
                    +    AG H    ALA+  LG + R++M     + +   V R    GAEV+
Sbjct: 64  LSAEALARGVVTASAGNHAQGVALAAHTLGCRARVFMPHTTPDIKVQAVAR---YGAEVV 120

Query: 158 PVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQIL 217
                     DA     R+             T   P  +P  V   Q  +G E   Q  
Sbjct: 121 LYGDNFDDACDAALADARE----------RDSTFVPPFDHP-HVIAGQGTVGMEILQQTT 169

Query: 218 EREGRLPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRV 276
           +      DA+   +GGG  A G+ A     +  + + GVEP             +     
Sbjct: 170 QL-----DAIFVPIGGGGLAAGICAYVKRVKPQIRIFGVEP--------SDADSMYQALE 216

Query: 277 GIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAF 336
           G               ++        G+    VG     L        V + +DE   A 
Sbjct: 217 GGAP-----------VRLAHVGRFCDGVAVRQVGAYSFALCRQYLDGVVRVDNDEVCAAI 265

Query: 337 KTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSG-RGDKDIFTV 387
           K + +    I     + ALA  LK  +    K   LV   SG   + D    
Sbjct: 266 KDVFVDTRSILEPSGALALAG-LKAWQRREQKGGTLVAIASGANMNFDQLRY 316


>UniRef50_Q2RHT1 Cysteine synthase n=6 Tax=Bacteria RepID=Q2RHT1_MOOTA
          Length = 306

 Score =  180 bits (456), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 63/338 (18%), Positives = 117/338 (34%), Gaps = 51/338 (15%)

Query: 53  AGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE---IIAE 109
               T + +   +       +YLK E    GG+ K    L     A+  G+ +    I E
Sbjct: 10  LIGQTPILRLNRLVED-GMEVYLKIEFFNPGGSVKDRIALSMITAAEADGRLKPGDTIVE 68

Query: 110 TGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDA 169
             +G  G+  A+ +A+ G +  + M              +   GAE +        +K A
Sbjct: 69  PTSGNTGIGLAMVAAVRGYRLILVMPETM---SIERRKLLAAYGAEFVLTPGNLG-MKGA 124

Query: 170 CNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIA 229
            ++A      +    ++M          P      ++    E   Q+        DA +A
Sbjct: 125 VDKANELVRENP--GYFMPQ----QFENPANPAIHRQTTAREILEQM----DGKVDAFVA 174

Query: 230 CVGGGSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQ 288
            VG G    G+      E   V ++ VEP    + +G  G P  H   GI  G   P+  
Sbjct: 175 GVGTGGTLTGVGEVLKKEIPGVRIVAVEPAASPVLSG--GQPGPHKIQGIGAGFVPPV-- 230

Query: 289 TEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPA 348
                                      L      + +++T+++A+E  + L   EG++  
Sbjct: 231 ---------------------------LRREVVDEIITVTNEDAMETARRLAREEGLLVG 263

Query: 349 LESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFT 386
           + S  A   AL++ R     ++ ++      G++ + T
Sbjct: 264 ISSGAAAFAALQVARRLGRGKR-VLAIAPDTGERYLST 300


>UniRef50_A2QU10 Function: catalyzes L-serine to D-serine racemization n=22
           Tax=Dikarya RepID=A2QU10_ASPNC
          Length = 377

 Score =  179 bits (455), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 69/399 (17%), Positives = 121/399 (30%), Gaps = 79/399 (19%)

Query: 38  DPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNT----------------------TLYL 75
            P    +   L++ Y  R T L  CQ +    +                         + 
Sbjct: 12  TPSAIHEAYSLIQPYVHR-TPLLTCQTLNTIASAPQSPEALSGTSSEGQTPANPKFRFFF 70

Query: 76  KREDLLHGGAHKTNQVLGQALLAKRMG-----KTEIIAETGAGQHGVASALASALLGLKC 130
           K E+    GA K        L           +   +    +G H  A ALA++ LG+  
Sbjct: 71  KCENYQRIGAFKARGAFHALLRLIAERGQEDVQKRGVITHSSGNHAQALALAASTLGVPA 130

Query: 131 RIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGT 190
            I M +         +   R  GAEVI   S S   +    +                G 
Sbjct: 131 YIIMPSIST---PSKIAGTRSHGAEVIFSGSTSVEREAVVADVQAK-----------TGA 176

Query: 191 AAGPHPYPTIVREFQRMIGEETKAQILEREGRLP-----------DAVIACVGGGSNAIG 239
              P      +   Q     E + Q  E     P           DAV   +GGG    G
Sbjct: 177 ILIPPYDDFNIICGQGTTALELEEQYRELVAEKPNLSIRQGSTALDAVFTPIGGGGLNSG 236

Query: 240 MFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYS 299
           +   F ++    + G EP   G +           R G+  G + P + T         +
Sbjct: 237 VAT-FFSDKTTKVFGAEPSFEGAD---------DCRRGLDAGERVPAVSTL--------T 278

Query: 300 ISAGLDFP-SVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALA-- 356
           I+ GL  P  +       N    A   ++T+++   A + +     ++    +   LA  
Sbjct: 279 IADGLRTPVGLLNWEVISNRNKVAGVYAVTEEQIKAAMRLVLERMKVVVEPSAVVGLAVC 338

Query: 357 ----HALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDIL 391
                  +++ +   +   + +  SG G+  +  +  + 
Sbjct: 339 LYNEGFRRLVEKEAPEGWDVGIVFSG-GNTTVEAIGKLF 376


>UniRef50_UPI000180D414 PREDICTED: similar to K01C8.1 n=1 Tax=Ciona intestinalis
           RepID=UPI000180D414
          Length = 327

 Score =  179 bits (455), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 65/359 (18%), Positives = 124/359 (34%), Gaps = 55/359 (15%)

Query: 39  PEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLA 98
            +      D ++    R   + K   +       ++LK E++   G+ K+  V+ Q   A
Sbjct: 13  YDIVRASRDCVRTPLLR--NVEKLGFLDCPDEVEVHLKLENMQVTGSFKSRGVVVQLAKA 70

Query: 99  KRM---GKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAE 155
             +   GK  ++    AG +G A A A    GLK  + M     E        ++  G +
Sbjct: 71  PSLVTSGKRSLVTI-SAGNYGKAFAHACYQRGLKGTVIMPLTAPES---RERIIQSKGCD 126

Query: 156 VIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPT-IVREFQRMIGEETKA 214
           VI   S     K      +++     +            HP+    +       G E   
Sbjct: 127 VIRTESSELMTK------VKELIHEKDMTFL--------HPFDDLNLIAGYGSAGLEILE 172

Query: 215 QILEREGRLPDAVIACVGGGSNAIGMFAD--FINETNVGLIGVEPGGHGIETGEHGAPLK 272
           ++       PD V+ C GGG    G+ A   +    +  +  VEP               
Sbjct: 173 EV------NPDIVLVCCGGGGLVSGISAAIKYKGFKDTKIYAVEPETANTMQRS------ 220

Query: 273 HGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEA 332
                        + Q     ++ ++S++AGL  P  G        +     ++++D E 
Sbjct: 221 -------------LAQNSAATLQTAHSLAAGLAPPFAGNNTFQHVKSLTDGVLTVSDKEI 267

Query: 333 LEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDIL 391
            +A + L    G+I     + A A  +    + P+ +  +VV ++G G+     +  + 
Sbjct: 268 AKATRVLYNK-GLIVEPSGAAAFAALV--TGKVPELKGTVVVLVTG-GNASTEELSKVF 322


>UniRef50_A8MA47 Pyridoxal-5'-phosphate-dependent protein beta subunit n=1
           Tax=Caldivirga maquilingensis IC-167 RepID=A8MA47_CALMQ
          Length = 343

 Score =  179 bits (455), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 62/357 (17%), Positives = 122/357 (34%), Gaps = 45/357 (12%)

Query: 40  EFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAK 99
           E       +        T L + + +++     +YLK E+L   G+ K   V        
Sbjct: 19  EAWEFTRRMESMGYVIRTPLYRSERLSSN-GLNVYLKLENLQRSGSFKVRGVFFAVHKYM 77

Query: 100 RMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPV 159
           R G    +     G H VA A  +++L ++  + +       Q   V  M   GAEVI  
Sbjct: 78  RDGYEHFLT-VSTGNHAVALAYVASILRVRATVVVPETT---QRSKVEDMERYGAEVIKY 133

Query: 160 HSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILER 219
                +  +A  +AL     S +    ++ T          V      IG E    +   
Sbjct: 134 ---GRSYVEAEKKALE--ISSSDQRIKLIHTF-----NDYYVIAGHTTIGLEILEDLP-- 181

Query: 220 EGRLPDAVIACVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGI 278
                DA++  +GGG+   G+     + + +  + GV+P         +   LK G+  +
Sbjct: 182 ---NVDAILIPLGGGALPAGVSYLVRHVKPSTKVYGVQPENAPF----YVLSLKEGKPVV 234

Query: 279 YFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKT 338
              ++               +I+ GL     G              + + + +   A   
Sbjct: 235 LSSIE---------------TIADGLA-SRPGEIPFEYIRRYLDGVLLVNERDIERAVYV 278

Query: 339 LCLHEGIIPALESSHALAHAL--KMMRENPDKEQ-LLVVNLSGRGDKDIFTVHDILK 392
           L  +E +I     + A+   +   ++++        +V  ++G    D+  +  IL+
Sbjct: 279 LLKYEHVIAEGAGAIAIGPIINGDLVKKLGQGGVYNVVAVITGS-HIDVERLRKILE 334


>UniRef50_A1WTA6 L-threonine synthase n=12 Tax=Bacteria RepID=A1WTA6_HALHL
          Length = 379

 Score =  179 bits (455), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 62/339 (18%), Positives = 109/339 (32%), Gaps = 31/339 (9%)

Query: 57  TALTKCQNITAGTN--TTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQ 114
           T L +   I A       LY+K E L   G+ K   +      A   G   II     G 
Sbjct: 34  TPLIQLTRIPAELGRDVDLYVKFEGLNPTGSFKDRGMTMAVTKAVEQGAKAIICA-STGN 92

Query: 115 HGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEAL 174
              ++A  +A  G+ C + +    +         M   GA+V+ +           +  +
Sbjct: 93  TSASAAAYAARAGISCFVLIPDGKIAMGKLAQAIM--HGAQVLQIRGN-------FDAGM 143

Query: 175 RDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGG 234
           R      E A   +  +  P+       + Q+    E   ++     R PD     VG  
Sbjct: 144 RLVKELAEHAPLTIVNSINPYR-----LQGQKTAAFEIIEELE----RAPDYHCLPVGNA 194

Query: 235 SNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTE---- 290
            N    +  +      G  G E                   V     M            
Sbjct: 195 GNITAHWIGYSEC--AGRTGDEQLTAACAFCGGQCRYASALVERRPRMVGYQASGSAPFL 252

Query: 291 -DGQIEESYSISAGLDF--PSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIP 347
             G + E  +++  +    P        +       +  ++D+E L+A + L  HEG+  
Sbjct: 253 RGGPVAEPETVATAIRIGDPQSWDYAQAVREESGGWFDELSDEEILQAQRMLADHEGVFC 312

Query: 348 ALESSHALAHALKMMRENP-DKEQLLVVNLSGRGDKDIF 385
              S+ ++A A++ +R     +   +V  L+G G KD  
Sbjct: 313 EPASATSVAGAMRDIRSGRIPEGSTVVCTLTGHGLKDPD 351


>UniRef50_Q5WLV3 Cysteine synthase n=48 Tax=Bacteria RepID=Q5WLV3_BACSK
          Length = 312

 Score =  179 bits (454), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 60/334 (17%), Positives = 114/334 (34%), Gaps = 51/334 (15%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTE---IIAETGAG 113
           T L K   +    +  +YLK E    G + K    L     A+  G+ +    I E  +G
Sbjct: 14  TPLVKLNRLATAEHADVYLKLEYQNPGSSVKDRIALAMVNAAEESGELKPGATIVEPTSG 73

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
             G+  A+ +A  G K ++ M              +R  GAE++    G   +  A  +A
Sbjct: 74  NTGIGLAMVAAAKGYKTKLVMPETM---SMERRNLLRAYGAELVLTP-GPEGMGGAIRKA 129

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
                      H+M              +  +   G+E   Q+  +     D  +A +G 
Sbjct: 130 TELAKQ---DGHFMPQ----QFENSANPKIHRETTGKELLKQVDGQL----DGFVAGIGT 178

Query: 234 GSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDG 292
           G    G           + ++ +EP    + +G    P  H   GI  G    ++ T   
Sbjct: 179 GGTITGAGGLLKEHFPELKIVAIEPKDSPVLSGGKPGP--HKLQGIGPGFVPGILNTNV- 235

Query: 293 QIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESS 352
                                           + ++ ++A E  +     EGI+  + S 
Sbjct: 236 ----------------------------YDSVLQVSTEQAFEYARRAAREEGILGGISSG 267

Query: 353 HALAHALKMMRENPDKEQLLVVNLSGRGDKDIFT 386
            A+  AL++ +E    ++++ +  S  G++ + T
Sbjct: 268 AAIYGALELAKELGPGKKVVAIIPS-NGERYLST 300


>UniRef50_B8J2I1 Cysteine synthase n=1 Tax=Desulfovibrio desulfuricans subsp.
           desulfuricans str. ATCC 27774 RepID=B8J2I1_DESDA
          Length = 306

 Score =  179 bits (454), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 68/347 (19%), Positives = 121/347 (34%), Gaps = 54/347 (15%)

Query: 53  AGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG---KTEIIAE 109
           A   T + +   ++     T++LK E+   GG+ K          A + G      ++ E
Sbjct: 8   AIGNTPMLRLD-LSKDMPGTVWLKLENRNPGGSIKDRVAFHLIENALQWGELEPGGLVVE 66

Query: 110 TGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDA 169
             +G  G+  AL SA+ GL+C + M              +R +GAE++   +    +  A
Sbjct: 67  ATSGNMGIGIALVSAVRGLRCVLAMPESM---SLERRNLLRGLGAELVLTPAARG-MTGA 122

Query: 170 CNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIA 229
             EA R             G   G    P  V+   +  G E  +  + +     D ++A
Sbjct: 123 VEEARRIAEEQG-------GFIPGQFTNPEAVQAHYKTTGPEIYSDSVGKM----DVLVA 171

Query: 230 CVGGGSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQ 288
            VG GS+  G             +I VEP    + +G   +P  H   GI  G       
Sbjct: 172 GVGSGSSITGAGRFLKERIPGFRVIAVEPAASPVISGGAASP--HLIQGIGAGFIP---- 225

Query: 289 TEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPA 348
                                    A L+ +   + +    +EAL+  + L   +GI+  
Sbjct: 226 -------------------------AILDRSLLDEILLADGEEALDTARLLMR-QGIVAG 259

Query: 349 LESSHALAHALKMM--RENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
           + +   +  AL++   +E   K  +     +G          D+ +A
Sbjct: 260 ISTGANVRAALQVAARQEMAGKNIVTFACDTGERYMSTRLFTDMAQA 306


>UniRef50_A6RLV9 Putative uncharacterized protein n=3 Tax=Sordariomyceta
           RepID=A6RLV9_BOTFB
          Length = 348

 Score =  179 bits (453), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 60/358 (16%), Positives = 123/358 (34%), Gaps = 46/358 (12%)

Query: 54  GRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEII--AETG 111
              T L +   ++      ++LK E+L   G+ K+  +    + +        +    + 
Sbjct: 20  WIKTPLVRSAALSRHAGCNVWLKLENLQPSGSFKSRGIGNLLIRSLPPNPHTPVHFYCSS 79

Query: 112 AGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACN 171
            G  G+A A A+  L   C I +           + +++L+ AEV+   +      +A  
Sbjct: 80  GGNAGLACAHAAFSLKRPCTIVVPMTTSS---HMISKIKLLKAEVVQTGNH---WSEADR 133

Query: 172 EALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACV 231
               +   +     Y       P  +P I  E    +  E + ++        DAVI  +
Sbjct: 134 YLREELLANDANGVY-----VPPFDHPEIW-EGNSGVITEIEEEVRGLGIHSLDAVICSI 187

Query: 232 GGGSNAIGMFADFIN------ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAP 285
           GGG    G+             +   +IGVE  G    T    A +K   +    G+ + 
Sbjct: 188 GGGGLFNGIMKGLEESGRLGAHSGTKVIGVETTG----TASFHAAMKREELVRLDGIDS- 242

Query: 286 MMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGI 345
           +  +       + S+  GL +                  V + D E+++    +   E I
Sbjct: 243 IATSLGATQVAAKSLEWGLKY------------RKNVRSVVLGDAESVDGMVWMADEERI 290

Query: 346 IPALESSHALAHA--------LKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKARG 395
           +       ++A A        L+   E  + + +++V   G  +  + T+ +  +  G
Sbjct: 291 LVESACGVSVAVATNGMLKKILEEDGETVEGKNVVIVVCGGS-NISLKTLAEYRERFG 347


>UniRef50_Q0C326 Pyridoxal-phosphate-dependent enzyme n=8 Tax=Bacteria
           RepID=Q0C326_HYPNA
          Length = 331

 Score =  179 bits (453), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 71/362 (19%), Positives = 115/362 (31%), Gaps = 37/362 (10%)

Query: 34  SAQKDPEFQAQFN-DLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVL 92
                P F+     +  +    R T +     +       L +K E L   G+ K    +
Sbjct: 3   QTLTLPAFEDVLAAEQRQRGVVRETPVLSHPALDEAAGAELLIKAECLQVTGSFKIRGAM 62

Query: 93  GQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLM 152
            +       GK   +    +G H    A A+ LLG+   I M +   + +   V      
Sbjct: 63  NRLAQVPPEGKAAGVVAFSSGNHAQGVARAARLLGMPALIVMPSDAPQVKVDGVLAD--- 119

Query: 153 GAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEET 212
           G EV      +   ++ C     +            G A  P      +   Q   G E 
Sbjct: 120 GGEVYLYDRNTENREEICARLAAE-----------RGAAIVPSYDDFDIIAGQGTAGLEF 168

Query: 213 KAQILEREGRLPDAVIACVGGGSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPL 271
             Q  E  G+  D +I+  GGG    G+   F        +   EP  H     +    L
Sbjct: 169 ARQA-EAMGKPLDHLISPAGGGGLINGVALAFGQLSPATKIWAAEPEAH----DDWARSL 223

Query: 272 KHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDE 331
           + G                      + SI   +  P  G     L     A    ++D++
Sbjct: 224 EAGE--------------ILANAPGTRSICDAILTPQPGYLTFALGQRQLAGAFRVSDED 269

Query: 332 ALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDIL 391
             EA +    +  ++     S ALA AL  + E   K + + + +SG G+ D      IL
Sbjct: 270 VREAMRMAFRYLRVVAEPGGSAALAAALSGLPEAL-KGKRIGIIVSG-GNVDAAQYAAIL 327

Query: 392 KA 393
            A
Sbjct: 328 GA 329


>UniRef50_C9KLW2 Threonine synthase n=2 Tax=Veillonellaceae RepID=C9KLW2_9FIRM
          Length = 342

 Score =  179 bits (453), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 61/311 (19%), Positives = 113/311 (36%), Gaps = 39/311 (12%)

Query: 72  TLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCR 131
              LK E LL  G+ K     G       +G  + IA   +G  G + A  +A   ++C 
Sbjct: 70  DFLLKMEHLLPTGSFKDRGACGMINALHDLGIKK-IALDSSGNAGASMAAYAAAADMECT 128

Query: 132 IYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTA 191
           +Y      + +   V ++   GA+++ V +G         +A      +   A+Y     
Sbjct: 129 VYTPDDISQEK---VKQIEAYGAKIVKVANGR-------MKACAAVKQNLGDAYYA---- 174

Query: 192 AGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVG 251
              H Y  +  E  + +  E   Q+      +PD +   VG G+  IG+F  F+      
Sbjct: 175 --SHVYNPLFFEGIKSMAHELYDQL---GHHVPDYIFMPVGNGTMLIGLFLGFME----- 224

Query: 252 LIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGP 311
            IG  P    +++ +     +          +  + +                    +  
Sbjct: 225 -IGRLPHFVAVQSSKCAPLYEAYHEVPASPKRTTIAEAIRIT-----------KPKRLKE 272

Query: 312 QHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQL 371
               +  +G  D +++ D + L+A K L    GI   + S+ ALA A++           
Sbjct: 273 MVKAIRDSG-GDVITVPDKDILKAQKYLSHR-GIYVEMTSAAALAGAVQFFENGKPDNYK 330

Query: 372 LVVNLSGRGDK 382
           +V+ L+G G K
Sbjct: 331 VVIPLTGNGLK 341


>UniRef50_A9VDJ3 Cysteine synthase n=1 Tax=Monosiga brevicollis RepID=A9VDJ3_MONBE
          Length = 327

 Score =  178 bits (452), Expect = 3e-43,   Method: Composition-based stats.
 Identities = 56/337 (16%), Positives = 100/337 (29%), Gaps = 43/337 (12%)

Query: 66  TAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEI-----IAETGAGQHGVASA 120
              T   + +K E +  GG+ K    L     A+  G+ +      I E   G  G+A A
Sbjct: 12  EPATGCQILVKAEHMNPGGSVKDRAALKLLRQAEARGQLKPHTGQCIVEGTGGNTGIALA 71

Query: 121 LASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGS 180
           +    LG K    M  K    +S     M L GAE     +     +    + +R  +  
Sbjct: 72  MLGTSLGYKTIFAMPEKTSRDKS---NLMELFGAETHRQPAVPFNDEQHYYQVIRRLAQQ 128

Query: 181 YETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGM 240
                                   +   G E   Q   R     D      G G    G+
Sbjct: 129 EGN------FGPDQFENTDNAAAHREGTGPEIWRQTRGRI----DGFTCASGTGGTMAGV 178

Query: 241 FADFI-NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYS 299
            +      + + +   +P G G+                       +   +        +
Sbjct: 179 SSYLKGRNSKIAVWLTDPMGSGLAA--------------------YVNHHDTSFPASGST 218

Query: 300 ISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHAL 359
           ++ G+    +                  TD+EA+     L  HEG+     ++  +  A+
Sbjct: 219 VAEGV---GITRLTNNFKEARVDGAFKGTDEEAITMMYYLARHEGLYVGPSAALNVVGAI 275

Query: 360 KMMRE-NPDKEQLLVVNLSGRGDKDIFTVHDILKARG 395
           K+ R+  P+K  + V+  +G   +        LK   
Sbjct: 276 KLARKLGPNKCVVTVLCDTGDRYRATVYNEAWLKEHN 312


>UniRef50_A9VB30 Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9VB30_MONBE
          Length = 350

 Score =  178 bits (452), Expect = 3e-43,   Method: Composition-based stats.
 Identities = 61/341 (17%), Positives = 111/341 (32%), Gaps = 29/341 (8%)

Query: 53  AGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG---KTEIIAE 109
               T L +   ++  T   + LK E +  GG+ K    L     A+R G       + E
Sbjct: 8   LIGRTPLVEATALSKRTGCRILLKMEAMNPGGSSKDRIALNIIETAERDGWLKPGGTVIE 67

Query: 110 TGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDA 169
             AG  G++ AL +   G +C I M       +      +R +GAEV  V + S      
Sbjct: 68  GTAGSTGISLALLARARGYRCIIVMADDMAMEKEI---LLRTLGAEVHRVKAVSFVNNQH 124

Query: 170 CNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIA 229
                   +       Y                      G E  AQ       + DA + 
Sbjct: 125 FCRVAEALATEIPGGFY-----VNQFENAANFLAHYHHTGPEIWAQ----TSGVIDAFVM 175

Query: 230 CVGGGSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQ 288
             G G    G+        +++ ++  +P G  +        +   +       +     
Sbjct: 176 GAGTGGTLAGVGTFLKEQSSDIHVVLADPPGSALYRKVKNGVIYTSQQAEQRLQRNRYDT 235

Query: 289 TEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPA 348
             +G   +  +            ++  L      D   +TD E++     L  HEG+   
Sbjct: 236 ILEGVGIDRLT------------RNFALGQAAVDDAYQVTDAESVTMAYWLLAHEGLFIG 283

Query: 349 LESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHD 389
             S+  L  A+K+ R  P     +V  +  +G++ +  V++
Sbjct: 284 SSSALNLVAAVKLARTLPAGS-TIVTCICDQGNRGMSKVYN 323


>UniRef50_A8ABB1 L-threonine synthase n=45 Tax=cellular organisms RepID=A8ABB1_IGNH4
          Length = 408

 Score =  178 bits (452), Expect = 3e-43,   Method: Composition-based stats.
 Identities = 72/380 (18%), Positives = 136/380 (35%), Gaps = 43/380 (11%)

Query: 18  PQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRP-------TALTKCQNITAGTN 70
           P+ L P        F    +       F +LL   +G P       T L + + +     
Sbjct: 36  PEELPPF-----SEFTKRSRMKGIWR-FAELLPVKSGSPVTMGEGNTPLIRLEKLEKVIG 89

Query: 71  TT-LYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLK 129
              LY K E     G+ K   +     +AK + K   +     G    ++A  SA  GLK
Sbjct: 90  VRRLYAKFEGANPTGSFKDRGMSLAVTVAKEV-KARAVVAASTGNTAASAAAYSARAGLK 148

Query: 130 CRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLG 189
             + + +  V      + +  L GA V+ +        DA  EA+++ +   E   Y L 
Sbjct: 149 TFLILPSGKVA--LGKLAQSLLHGAVVVELEGNF----DAALEAVKELAKMPE--FYPLN 200

Query: 190 TAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETN 249
           +      +     E Q+ +  E   +I   +  +       VG   N   ++  F     
Sbjct: 201 S------FNPWRLEGQKTLAFELFEEIGVPDVVV-----VPVGNAGNISAIWKGFKELKE 249

Query: 250 VGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSV 309
            G     P   G++           + G+     AP+       +  +  I   +++  +
Sbjct: 250 FGYSEALPKMVGVQAEGASPIASAFKAGL----NAPLFTDSPETVATAIRIGKPVNW--M 303

Query: 310 GPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENP-DK 368
               A   S G   +  ++D E + A + L   EG+      + +LA  +++  E   + 
Sbjct: 304 KAWKAVTESGG--TFEVVSDSEIIRAQRLLAREEGVAAEPAGAASLAGVVRLASEGYFNG 361

Query: 369 EQLLVVNLSGRGDKDIFTVH 388
           ++++ V ++G G KD  +V 
Sbjct: 362 DEVVTVVVTGHGLKDPDSVK 381


>UniRef50_Q5KGT7 Serine family amino acid catabolism-related protein, putative n=4
           Tax=Dikarya RepID=Q5KGT7_CRYNE
          Length = 331

 Score =  178 bits (452), Expect = 3e-43,   Method: Composition-based stats.
 Identities = 58/336 (17%), Positives = 112/336 (33%), Gaps = 44/336 (13%)

Query: 54  GRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEI---IAET 110
              T L +   ++      + LK E++   G+ K+  +    L +      +       +
Sbjct: 16  WIKTPLVRSAALSKLAGCEILLKLENIQPSGSFKSRGIGNLVLQSVNSAPPDTPLHFYSS 75

Query: 111 GAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDAC 170
             G  G+A   A++ LG    + +       +   + ++R  GA    V     T  +A 
Sbjct: 76  SGGNAGLACVNAASTLGYPSSVIVPLST---KPFMIDKLRTAGAT--EVIQTGQTWFEAD 130

Query: 171 NEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIAC 230
                +         Y+      P  +  I  +    + +E   ++      +PDA++  
Sbjct: 131 KHLQEEILARDPNGIYLP-----PFDHSDIW-QGAATMVDEIVQELT----HVPDAIVCS 180

Query: 231 VGGGSNAIGMFADFI---NETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMM 287
           VGGG   IG+         E    ++ VE  G           +K G++    G+     
Sbjct: 181 VGGGGLMIGVCKGLERLDKEKKAKVVAVETLG----AESLHKSVKAGQLITLPGIA---- 232

Query: 288 QTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIP 347
                      S++  L   +V  +        +     ++D EALEA       E I+ 
Sbjct: 233 -----------SLATSLGATTVAAKALEYALQPQVRSTVVSDKEALEACIRFLDDERILV 281

Query: 348 ALESSHALA----HALKMMRENPDKEQLLVVNLSGR 379
                  LA      LK + +   K ++++V   G 
Sbjct: 282 EPACGATLAMVYSGKLKDVLKLDAKSKVVLVVCGGS 317


>UniRef50_A3ERN7 Cysteine synthase n=2 Tax=Leptospirillum sp. Group II
           RepID=A3ERN7_9BACT
          Length = 312

 Score =  178 bits (452), Expect = 3e-43,   Method: Composition-based stats.
 Identities = 70/329 (21%), Positives = 108/329 (32%), Gaps = 51/329 (15%)

Query: 53  AGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG---KTEIIAE 109
               T L   +++T G +  +++K E    GG+ K          A+R G       I E
Sbjct: 15  LIGRTPLVALESMTRGLDRVVWVKLESRNLGGSVKDRPARYMVEQAERNGELAPGGRIVE 74

Query: 110 TGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDA 169
             +G  G+A A    L G    I M     +     V+ ++ +GAEV    +    +  A
Sbjct: 75  ATSGNTGIALAQIGVLKGYPVVIVMPEGVSQ---ERVYHLKALGAEVELTPA-RDGMAGA 130

Query: 170 CNEALRDWSGSYETAHYMLGTAAG-PHPYPTIVREFQRMIGEETKAQILEREGRLPDAVI 228
              A    S          G+        P       R  G E   Q+    GRLPD  +
Sbjct: 131 IRRAETLLSER-------PGSFMPRQFENPANPESHYRTTGPEILDQL----GRLPDGFV 179

Query: 229 ACVGGGSNAIGMFADFINETN-VGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMM 287
           A +G G    G+          V + G+EP    + +G    P  H   GI  G    ++
Sbjct: 180 AGIGTGGTITGVGRFLRERHEAVRIWGLEPASSAVLSGSSPGP--HRIQGIGAGFVPKIL 237

Query: 288 QTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIP 347
                   E                              I D  A+E  + L   EGI+ 
Sbjct: 238 DRSVCDKIEP-----------------------------IDDRTAIETMRRLTREEGIMA 268

Query: 348 ALESSHALAHALKMMRENPDKEQLLVVNL 376
            + S   +A AL + R  P    ++ +  
Sbjct: 269 GISSGANVAGALLLARTLPPGSHVVTIVC 297


>UniRef50_Q8YXP3 Cysteine synthase n=2 Tax=Nostoc sp. PCC 7120 RepID=Q8YXP3_ANASP
          Length = 365

 Score =  178 bits (452), Expect = 3e-43,   Method: Composition-based stats.
 Identities = 71/378 (18%), Positives = 121/378 (32%), Gaps = 56/378 (14%)

Query: 29  EEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTN-TTLYLKREDLLHGGAHK 87
           E  F     +              A     + K +NI+        +LK E    GG+ K
Sbjct: 11  ESIFKPQSGNHSKWKNTTATDVTQALGNVPIVKLRNISPVCAIAECFLKLESCNPGGSIK 70

Query: 88  TNQVLGQALLAKRMG---KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSP 144
               +     A+  G       I E+ +G  GV  A+  A+ G +  I + AK      P
Sbjct: 71  EKNAVYLVTCAEEEGLLVPGGTIIESSSGNFGVGLAMVGAVRGYRVIIVVDAKTP---PP 127

Query: 145 NVFRMRLMGAEVIPVH----SGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTI 200
               ++  GAE++ V       S +++ A  +  ++ + +   A Y        H  P  
Sbjct: 128 FRRMLKAYGAELVDVPLHEADESGSMQKARMKRAKELAATIPDAWYPC-----QHLNPLN 182

Query: 201 VREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINE-TNVGLIGVEPGG 259
                     E +A   +      DAV+  V      +G+          + +IGV+  G
Sbjct: 183 TEAHSYYTAREIEAHFADEL----DAVVVGVSTAGQIMGIARYLRPRFPKIRIIGVDVVG 238

Query: 260 HGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNST 319
             I                    K   M              + LD              
Sbjct: 239 SVIMGTS---------------AKPYKMTGIGLSFFPPNLDLSLLD-------------- 269

Query: 320 GRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGR 379
                  + +D A      L   EG++    +   +A  L + RE     ++L++N   R
Sbjct: 270 ---RAYIVPEDLAYSVCHALARREGLLLGASTGAIVAGGLHLARELGRGARILMIN-PDR 325

Query: 380 GDKDIFTVHD--ILKARG 395
           GD+ + TV+D   L+  G
Sbjct: 326 GDRYLETVYDSEWLERHG 343


>UniRef50_A7IFG1 Pyridoxal-5'-phosphate-dependent protein beta subunit n=2
           Tax=Rhizobiales RepID=A7IFG1_XANP2
          Length = 340

 Score =  178 bits (452), Expect = 3e-43,   Method: Composition-based stats.
 Identities = 67/351 (19%), Positives = 108/351 (30%), Gaps = 37/351 (10%)

Query: 44  QFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK 103
           +      +     T L +   I A     + +K E L H G+ K      +  L     +
Sbjct: 26  EAAYDRISGQVIRTPLFENAAINAACGARILIKPEMLQHTGSFKFRGASNRVALMSAAER 85

Query: 104 TEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGS 163
              I    +G H +A +  +A  G+K  I M +     +   V     +G  V       
Sbjct: 86  AGGIVAWSSGNHALAISAVAARHGIKATILMPSDAPRAK---VEGAERLGGTVR------ 136

Query: 164 ATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRL 223
             L D   E   +            G    P      V   Q  +G E   Q      +L
Sbjct: 137 --LYDRATEVREEIGADIAAR---TGAVIIPPYDDPHVIAGQGTVGLELAEQAAALGAQL 191

Query: 224 PDAVIACVGGGSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGM 282
             A+ AC G G    G             +   EP G      +    L  G+       
Sbjct: 192 DMALFACSG-GGLVAGAATALKARSPATLVYSAEPAGF----DDTARSLASGKP------ 240

Query: 283 KAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLH 342
                   +     + ++   L  P+ G     +N    A  V++TDDE   A + +   
Sbjct: 241 --------ERNAPGATTLCDALMVPTPGLLTFPINRALLAGGVAVTDDEVKAAMRLVYDT 292

Query: 343 EGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
             ++        LA    +  +   K + + V LSG G+ D  T    + A
Sbjct: 293 LKLVVEPGGVTPLAAV--LAGKVDAKGKTVGVVLSG-GNVDPDTYAACIGA 340


>UniRef50_Q10725 Phenylserine dehydratase n=62 Tax=Proteobacteria RepID=FSDH_BURPI
          Length = 326

 Score =  178 bits (451), Expect = 3e-43,   Method: Composition-based stats.
 Identities = 70/361 (19%), Positives = 103/361 (28%), Gaps = 47/361 (13%)

Query: 35  AQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQ 94
              D    A     LK +  R T +    +      T +  K E L   G  K       
Sbjct: 8   TLPDLSAIAGLRARLKQWV-RTTPVFDKTDFEPVPGTAVNFKLELLQASGTFKARGAFSN 66

Query: 95  ALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGA 154
            L      +   +    AG H V  A A+  LG+  ++ M           V   R  GA
Sbjct: 67  LLALDDDQRAAGVTCVSAGNHAVGVAYAAMRLGIPAKVVMIKTA---SPARVALCRQYGA 123

Query: 155 EVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTI-VREFQRMIGEETK 213
           EV+   +G                 S E   ++       HP+           +G E  
Sbjct: 124 EVVLAENGQTAFDTV------HRIESEEGRFFV-------HPFNGYRTVLGTATLGHEWL 170

Query: 214 AQILEREGRLPDAVIACVGGGSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLK 272
            Q         DAVI  +GGG    G+            +IGVEP G            +
Sbjct: 171 EQA-----GALDAVIVPIGGGGLMAGVSTAVKLLAPQCQVIGVEPEG----ADAMHRSFE 221

Query: 273 HGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEA 332
            G       M                SI+  L  P        L        V ++DDE 
Sbjct: 222 TGGPVKMGSM---------------QSIADSLMAPHTEQYSYELCRRNVDRLVKVSDDEL 266

Query: 333 LEAFKTLCLHEGIIPALESSHALAHAL-KMMRENPDKEQLLVVNLSGRGDKDIFTVHDIL 391
             A + L     +      + A A  +  +  E   K   +++  +   + D  T    L
Sbjct: 267 RAAMRLLFDQLKLATEPACATATAALVGGLKAELAGKRVGVLLCGT---NTDAATFARHL 323

Query: 392 K 392
            
Sbjct: 324 G 324


>UniRef50_Q59447 Cysteine synthase n=20 Tax=Bacteria RepID=CYSK_FLAS3
          Length = 307

 Score =  178 bits (451), Expect = 4e-43,   Method: Composition-based stats.
 Identities = 57/296 (19%), Positives = 92/296 (31%), Gaps = 50/296 (16%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG---KTEIIAETGAG 113
           T + K  N+    +  +++K E    GG+ K    L     A+  G   K   I E  +G
Sbjct: 13  TPVVKINNLFNS-DHEIWIKLEKSNPGGSIKDRIALAMIEDAEAKGLLNKDSTIIEPTSG 71

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
             G+  AL +A+ G K  + M              M   GAE +        +K A  +A
Sbjct: 72  NTGIGLALVAAVKGYKLILVMPESM---SIERRKIMEAYGAEFVLTPRE-KGMKGAIEKA 127

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
             + +     +             P  V+       +E      E      D VI  VG 
Sbjct: 128 -NELAEETPNSWIPR-----QFDNPANVKIHVETTAQEILQDFPEGL----DYVITGVGT 177

Query: 234 GSNAIGMFADFINE-TNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDG 292
           G +  G+      +  N+ +I VEP    + +G   AP                +Q    
Sbjct: 178 GGHITGIAKALKEKYPNLKVIAVEPELSPVLSGGSPAPH--------------PLQGLGA 223

Query: 293 QIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPA 348
                                + L+ T     +++  DEA E        EG+   
Sbjct: 224 GFVP-----------------SILDITLLDGVITVGKDEAYEYAINAAKKEGLFCG 262


>UniRef50_Q1D4S7 Cysteine synthase n=3 Tax=Deltaproteobacteria RepID=Q1D4S7_MYXXD
          Length = 330

 Score =  177 bits (450), Expect = 4e-43,   Method: Composition-based stats.
 Identities = 53/328 (16%), Positives = 98/328 (29%), Gaps = 42/328 (12%)

Query: 57  TALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG---KTEIIAETGAG 113
           T L +  +++  T   +  K E +  GG+ K     G    A+  G       I E  AG
Sbjct: 15  TPLLRIGSLSRQTGCEILAKAEFMNPGGSIKDRAAKGMIQCAEAQGLLKPGGAIFEGTAG 74

Query: 114 QHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEA 173
             G+   L     G +  + M       +      +  MG EV  V +      +     
Sbjct: 75  NTGIGLGLLGRERGYRVVVTMPDNQAREKY---ELLEAMGVEVRKVPAVPFANPNHFFHQ 131

Query: 174 LRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGG 233
            R  + +           A     P          G E   Q         D ++A VG 
Sbjct: 132 ARVLAEAQGGFW------ANQFENPANGDYHYETTGPEIWEQCE----GRVDVLVASVGS 181

Query: 234 GSNAIGMFADFIN-ETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDG 292
           G    G+          V ++ V+P G G+ T      ++                    
Sbjct: 182 GGTMGGVSRYLKEKNPAVRVVLVDPPGSGLFTYVREGRME-------------------- 221

Query: 293 QIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESS 352
                 SI+ G+    +             + + + D + +E    L   + ++    ++
Sbjct: 222 --GPGSSITEGI---GIMRLTENFRRAQVDEAMRLGDQDMVEMLYHLAREDALVVGTSAA 276

Query: 353 HALAHALKMMRENPDKEQLLVVNLSGRG 380
             +  A ++ R +  +   +V  L   G
Sbjct: 277 LNVRAAWELARRHRGEGLRIVTFLCDHG 304


>UniRef50_Q9X7F1 Probable threonine dehydratase biosynthetic n=24
           Tax=Actinomycetales RepID=THD1_MYCLE
          Length = 427

 Score =  177 bits (450), Expect = 5e-43,   Method: Composition-based stats.
 Identities = 74/343 (21%), Positives = 117/343 (34%), Gaps = 37/343 (10%)

Query: 52  YAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETG 111
               PT L     ++A T   +YLKREDL    ++K        +          +  + 
Sbjct: 28  PVVTPTPLQLSDRLSAITGAAVYLKREDLQTVRSYKLRGAYNLLVQLTDEEIAAGVVCSS 87

Query: 112 AGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACN 171
           AG H    A A   LG+  R+Y+ AK  +++      +R  G   I +  G +T   A  
Sbjct: 88  AGNHAQGVAYACRSLGVHGRVYVPAKTPKQKWDR---IRYHGGAFIELIVGRSTYDLAAA 144

Query: 172 EALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACV 231
            A+ D            G    P      V   Q  I  E   Q+       PD V+  V
Sbjct: 145 AAVDDIER--------TGATLVPPYDDVRVIAGQGTIAVELLEQLNTE----PDLVVVPV 192

Query: 232 GGGSNAIGMFADFINET-NVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTE 290
           GGG    GM       T N  ++GVEP G                         P+    
Sbjct: 193 GGGGCIAGMTTYLAERTANTAVLGVEPAGAAAMMAALA-------------AGEPVTLDY 239

Query: 291 DGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALE 350
             Q  +     A ++     P  A   +       ++ +     A   L  +EGII    
Sbjct: 240 VDQFVD----GAAVNRVGTLPYAALTAAGDMVSITTVDEGAVCTAMLDLYQNEGIIAEPA 295

Query: 351 SSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKA 393
            + ++A  L     + +    +V  +SG G+ D+    ++L+ 
Sbjct: 296 GALSVAGLL---ETDIEPGSTVVCLISG-GNNDVLRYGEVLER 334


  Database: uniref50.fasta
    Posted date:  Mar 8, 2010 10:38 AM
  Number of letters in database: 1,040,396,356
  Number of sequences in database:  3,077,464
  
Lambda     K      H
   0.312    0.143    0.386 

Lambda     K      H
   0.267   0.0439    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,485,202,307
Number of Sequences: 3077464
Number of extensions: 111175162
Number of successful extensions: 398817
Number of sequences better than 1.0e-01: 250
Number of HSP's better than  0.1 without gapping: 1074
Number of HSP's successfully gapped in prelim test: 1008
Number of HSP's that attempted gapping in prelim test: 390733
Number of HSP's gapped (non-prelim): 2931
length of query: 397
length of database: 1,040,396,356
effective HSP length: 131
effective length of query: 266
effective length of database: 637,248,572
effective search space: 169508120152
effective search space used: 169508120152
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.3 bits)
S2: 94 (40.7 bits)
