Phyre 2 Results for P76361

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Email | l.a.kelley@imperial.ac.uk
Description | P76361
Date | Thu Jan 5 12:22:20 GMT 2012
Unique Job ID | 6065ac5873f4750b

Summary |

Top model
Image coloured by rainbow N → C terminus
| Close Jmol

Model (left) based on template d1vlpa1
Top template information
Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:Monomeric nicotinate phosphoribosyltransferase N-terminal domain-like
Confidence and coverage
Confidence: | 61.7% | Coverage: | 7%
35 residues ( 7% of your sequence) have been modelled with 61.7% confidence by the single highest scoring template.
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3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | L | Q | I | V | G | A | L | I | L | L | I | A | G | F | A | I | L | R | L | L | F | R | A | L | I | S | T | A | S | A | L | A | G | L | I | L | L | C | L | F | G | P | A | L | L | A | G | Y | I | T | E | R | I | T | R | L | F | H | I
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | R | W | L | A | G | V | F | L | T | I | A | G | M | I | I | S | F | M | W | G | L | D | G | K | H | I | A | L | E | A | H | T | F | D | S | V | K | F | I | L | T | T | A | L | A | G | G | L | L | A | V | P | L | Q | I | K | N | I | Q | Q
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  | ? |  |  | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | N | G | I | T | P | E | D | I | S | K | E | I | N | G | Y | Y | C | C | F | Y | T | A | F | F | L | M | A | C | S | A | C | A | P | L | I | A | L | Q | Y | D | I | S | P | S | L | M | W | W | G | G | L | L | Y | W | L | A | A | L | V | T
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240
Sequence |  | L | L | W | A | A | S | Q | I | Q | A | L | K | K | L | T | C | A | I | S | Q | T | L | E | E | Q | P | V | L | N | S | K | S | W | L | T | S | L | Q | N | D | Y | S | L | P | D | S | L | T | E | R | I | W | L | T | L | I | S | Q | R | I
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300
Sequence |  | S | R | G | E | L | R | E | F | E | L | A | D | G | N | W | L | L | N | N | A | W | Y | E | R | N | M | A | G | F | N | E | Q | L | K | E | N | L | S | F | T | P | D | E | L | K | T | L | F | R | N | R | L | N | L | S | P | E | A | N | D
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360
Sequence |  | D | F | L | D | R | C | L | D | G | G | D | W | Y | P | F | S | E | G | R | R | F | V | S | F | H | H | V | D | E | L | R | I | C | A | S | C | G | L | T | E | V | H | H | A | P | E | N | H | K | P | D | P | E | W | Y | C | S | S | L | C
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  | ? | ? | ? |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420
Sequence |  | R | E | T | E | T | L | C | Q | E | I | Y | E | R | P | Y | N | S | F | I | S | D | A | T | A | N | G | L | I | L | M | K | L | P | E | T | W | S | T | N | E | K | M | F | A | S | G | G | Q | G | H | G | F | A | A | E | R | G | N | H | I
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  | ? | ? | ? |  |  | ? | ? | ? |  | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  | ? |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480
Sequence |  | V | D | R | V | R | L | K | N | A | R | I | L | G | D | N | N | A | R | N | G | A | D | R | L | V | S | G | T | E | I | Q | T | K | Y | C | S | T | A | A | R | S | V | G | A | A | F | D | G | Q | N | G | Q | Y | R | Y | M | G | N | N | G
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? |  |  | ? | ? |  | ? | ? |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  | ? |  | ? |  | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510
Sequence |  | P | M | Q | L | E | V | P | R | D | Q | Y | A | G | A | V | E | T | M | R | N | K | I | R | E | G | K | V | E | E | R
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| d1vlpa1 |

### PDB 1vlp chain A domain 1

Region: 266 - 304
Aligned: 35
Modelled: 39
Confidence: 61.7%
Identity: 26%
Fold: alpha/beta-Hammerhead
Superfamily: Nicotinate/Quinolinate PRTase N-terminal domain-like
Family: Monomeric nicotinate phosphoribosyltransferase N-terminal domain-like

Phyre2
2 |
| d1us7b_ |

### PDB 1us7 chain B

Region: 293 - 314
Aligned: 22
Modelled: 22
Confidence: 45.1%
Identity: 32%
Fold: Hsp90 co-chaperone CDC37
Superfamily: Hsp90 co-chaperone CDC37
Family: Hsp90 co-chaperone CDC37

Phyre2
3 |
| c1us7B_ |

### PDB 1us7 chain B

Region: 293 - 314
Aligned: 22
Modelled: 22
Confidence: 45.1%
Identity: 32%
PDB header:chaperone
Chain: B: PDB Molecule:hsp90 co-chaperone cdc37;
PDBTitle: complex of hsp90 and p50

Phyre2
4 |
| c2puyA_ |

### PDB 2puy chain A

Region: 299 - 358
Aligned: 42
Modelled: 42
Confidence: 39.5%
Identity: 26%
PDB header:transcription
Chain: A: PDB Molecule:phd finger protein 21a;
PDBTitle: crystal structure of the bhc80 phd finger

Phyre2
5 |
| d2f7fa2 |

### PDB 2f7f chain A domain 2

Region: 266 - 345
Aligned: 73
Modelled: 80
Confidence: 35.7%
Identity: 25%
Fold: alpha/beta-Hammerhead
Superfamily: Nicotinate/Quinolinate PRTase N-terminal domain-like
Family: NadC N-terminal domain-like

Phyre2
6 |
| d1k0ga_ |

### PDB 1k0g chain A

Region: 480 - 509
Aligned: 30
Modelled: 30
Confidence: 33.6%
Identity: 17%
Fold: ADC synthase
Superfamily: ADC synthase
Family: ADC synthase

Phyre2
7 |
| d1ybea2 |

### PDB 1ybe chain A domain 2

Region: 266 - 304
Aligned: 39
Modelled: 39
Confidence: 33.2%
Identity: 26%
Fold: alpha/beta-Hammerhead
Superfamily: Nicotinate/Quinolinate PRTase N-terminal domain-like
Family: Monomeric nicotinate phosphoribosyltransferase N-terminal domain-like

Phyre2
8 |
| d1i7qa_ |

### PDB 1i7q chain A

Region: 481 - 509
Aligned: 29
Modelled: 29
Confidence: 32.7%
Identity: 17%
Fold: ADC synthase
Superfamily: ADC synthase
Family: ADC synthase

Phyre2
9 |
| d1i1qa_ |

### PDB 1i1q chain A

Region: 478 - 509
Aligned: 32
Modelled: 32
Confidence: 31.5%
Identity: 16%
Fold: ADC synthase
Superfamily: ADC synthase
Family: ADC synthase

Phyre2
10 |
| c1vlpA_ |

### PDB 1vlp chain A

Region: 266 - 304
Aligned: 35
Modelled: 39
Confidence: 30.0%
Identity: 26%
PDB header:transferase
Chain: A: PDB Molecule:nicotinate phosphoribosyltransferase;
PDBTitle: crystal structure of a putative nicotinate phosphoribosyltransferase2 (yor209c, npt1) from saccharomyces cerevisiae at 1.75 a resolution

Phyre2
11 |
| d1j96a_ |

### PDB 1j96 chain A

Region: 271 - 317
Aligned: 42
Modelled: 42
Confidence: 29.9%
Identity: 26%
Fold: TIM beta/alpha-barrel
Superfamily: NAD(P)-linked oxidoreductase
Family: Aldo-keto reductases (NADP)

Phyre2
12 |
| d1weqa_ |

### PDB 1weq chain A

Region: 317 - 357
Aligned: 41
Modelled: 41
Confidence: 28.6%
Identity: 24%
Fold: FYVE/PHD zinc finger
Superfamily: FYVE/PHD zinc finger
Family: PHD domain

Phyre2
13 |
| d1q5ma_ |

### PDB 1q5m chain A

Region: 271 - 317
Aligned: 42
Modelled: 47
Confidence: 28.3%
Identity: 33%
Fold: TIM beta/alpha-barrel
Superfamily: NAD(P)-linked oxidoreductase
Family: Aldo-keto reductases (NADP)

Phyre2
14 |
| d1zbdb_ |

### PDB 1zbd chain B

Region: 329 - 368
Aligned: 35
Modelled: 40
Confidence: 26.9%
Identity: 26%
Fold: FYVE/PHD zinc finger
Superfamily: FYVE/PHD zinc finger
Family: FYVE, a phosphatidylinositol-3-phosphate binding domain

Phyre2
15 |
| d1yira2 |

### PDB 1yir chain A domain 2

Region: 267 - 304
Aligned: 33
Modelled: 38
Confidence: 26.6%
Identity: 27%
Fold: alpha/beta-Hammerhead
Superfamily: Nicotinate/Quinolinate PRTase N-terminal domain-like
Family: Monomeric nicotinate phosphoribosyltransferase N-terminal domain-like

Phyre2
16 |
| d1ah4a_ |

### PDB 1ah4 chain A

Region: 271 - 317
Aligned: 42
Modelled: 47
Confidence: 25.2%
Identity: 33%
Fold: TIM beta/alpha-barrel
Superfamily: NAD(P)-linked oxidoreductase
Family: Aldo-keto reductases (NADP)

Phyre2
17 |
| c3o37D_ |

### PDB 3o37 chain D

Region: 299 - 356
Aligned: 40
Modelled: 40
Confidence: 24.0%
Identity: 38%
PDB header:transcription/protein binding
Chain: D: PDB Molecule:transcription intermediary factor 1-alpha;
PDBTitle: crystal structure of trim24 phd-bromo complexed with h3(1-10)k42 peptide

Phyre2
18 |
| d2alra_ |

### PDB 2alr chain A

Region: 271 - 317
Aligned: 45
Modelled: 47
Confidence: 22.6%
Identity: 29%
Fold: TIM beta/alpha-barrel
Superfamily: NAD(P)-linked oxidoreductase
Family: Aldo-keto reductases (NADP)

Phyre2
19 |
| d1hqta_ |

### PDB 1hqt chain A

Region: 271 - 317
Aligned: 47
Modelled: 47
Confidence: 21.8%
Identity: 32%
Fold: TIM beta/alpha-barrel
Superfamily: NAD(P)-linked oxidoreductase
Family: Aldo-keto reductases (NADP)

Phyre2
20 |
| d3ctaa2 |

### PDB 3cta chain A domain 2

Region: 267 - 321
Aligned: 46
Modelled: 55
Confidence: 21.5%
Identity: 22%
Fold: Reductase/isomerase/elongation factor common domain
Superfamily: Riboflavin kinase-like
Family: CTP-dependent riboflavin kinase-like

Phyre2
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Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | d1vlpa1 |
|  | 61.7 | 26 | Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:Monomeric nicotinate phosphoribosyltransferase N-terminal domain-like
2 | d1us7b_ |
|  | 45.1 | 32 | Fold:Hsp90 co-chaperone CDC37 Superfamily:Hsp90 co-chaperone CDC37 Family:Hsp90 co-chaperone CDC37
3 | c1us7B_ |
|  | 45.1 | 32 | PDB header:chaperone Chain: B: PDB Molecule:hsp90 co-chaperone cdc37; PDBTitle: complex of hsp90 and p50
4 | c2puyA_ |
|  | 39.5 | 26 | PDB header:transcription Chain: A: PDB Molecule:phd finger protein 21a; PDBTitle: crystal structure of the bhc80 phd finger
5 | d2f7fa2 |
|  | 35.7 | 25 | Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:NadC N-terminal domain-like
6 | d1k0ga_ |
|  | 33.6 | 17 | Fold:ADC synthase Superfamily:ADC synthase Family:ADC synthase
7 | d1ybea2 |
|  | 33.2 | 26 | Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:Monomeric nicotinate phosphoribosyltransferase N-terminal domain-like
8 | d1i7qa_ |
|  | 32.7 | 17 | Fold:ADC synthase Superfamily:ADC synthase Family:ADC synthase
9 | d1i1qa_ |
|  | 31.5 | 16 | Fold:ADC synthase Superfamily:ADC synthase Family:ADC synthase
10 | c1vlpA_ |
|  | 30.0 | 26 | PDB header:transferase Chain: A: PDB Molecule:nicotinate phosphoribosyltransferase; PDBTitle: crystal structure of a putative nicotinate phosphoribosyltransferase2 (yor209c, npt1) from saccharomyces cerevisiae at 1.75 a resolution
11 | d1j96a_ |
|  | 29.9 | 26 | Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP)
12 | d1weqa_ |
|  | 28.6 | 24 | Fold:FYVE/PHD zinc finger Superfamily:FYVE/PHD zinc finger Family:PHD domain
13 | d1q5ma_ |
|  | 28.3 | 33 | Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP)
14 | d1zbdb_ |
|  | 26.9 | 26 | Fold:FYVE/PHD zinc finger Superfamily:FYVE/PHD zinc finger Family:FYVE, a phosphatidylinositol-3-phosphate binding domain
15 | d1yira2 |
|  | 26.6 | 27 | Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:Monomeric nicotinate phosphoribosyltransferase N-terminal domain-like
16 | d1ah4a_ |
|  | 25.2 | 33 | Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP)
17 | c3o37D_ |
|  | 24.0 | 38 | PDB header:transcription/protein binding Chain: D: PDB Molecule:transcription intermediary factor 1-alpha; PDBTitle: crystal structure of trim24 phd-bromo complexed with h3(1-10)k42 peptide
18 | d2alra_ |
|  | 22.6 | 29 | Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP)
19 | d1hqta_ |
|  | 21.8 | 32 | Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP)
20 | d3ctaa2 |
|  | 21.5 | 22 | Fold:Reductase/isomerase/elongation factor common domain Superfamily:Riboflavin kinase-like Family:CTP-dependent riboflavin kinase-like
21 | c2riqA_ |
| not modelled | 20.6 | 28 | PDB header:transferase Chain: A: PDB Molecule:poly [adp-ribose] polymerase 1; PDBTitle: crystal structure of the third zinc-binding domain of human parp-1
22 | c3b4sA_ |
| not modelled | 20.0 | 56 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:protein luxt; PDBTitle: crystal structure of a luxt domain from vibrio2 parahaemolyticus rimd 2210633
23 | d1mn4a_ |
| not modelled | 19.6 | 45 | Fold:Common fold of diphtheria toxin/transcription factors/cytochrome f Superfamily:p53-like transcription factors Family:DNA-binding domain from NDT80
24 | c1yj7A_ |
| not modelled | 19.5 | 19 | PDB header:protein transport Chain: A: PDB Molecule:escj; PDBTitle: crystal structure of enteropathogenic e.coli (epec) type iii secretion2 system protein escj
25 | c2obnA_ |
| not modelled | 19.2 | 26 | PDB header:unknown function Chain: A: PDB Molecule:hypothetical protein; PDBTitle: crystal structure of a duf1611 family protein (ava_3511) from anabaena2 variabilis atcc 29413 at 2.30 a resolution
26 | c1xwhA_ |
| not modelled | 19.2 | 41 | PDB header:transcription Chain: A: PDB Molecule:autoimmune regulator; PDBTitle: nmr structure of the first phd finger of autoimmune2 regulator protein (aire1): insights into apeced
27 | c2jvnA_ |
| not modelled | 18.7 | 30 | PDB header:transferase Chain: A: PDB Molecule:poly [adp-ribose] polymerase 1; PDBTitle: domain c of human parp-1
28 | d2g5fa1 |
| not modelled | 16.8 | 10 | Fold:ADC synthase Superfamily:ADC synthase Family:ADC synthase
29 | d1q4qa_ |
| not modelled | 15.6 | 21 | Fold:Inhibitor of apoptosis (IAP) repeat Superfamily:Inhibitor of apoptosis (IAP) repeat Family:Inhibitor of apoptosis (IAP) repeat
30 | d1iega_ |
| not modelled | 15.2 | 39 | Fold:Herpes virus serine proteinase, assemblin Superfamily:Herpes virus serine proteinase, assemblin Family:Herpes virus serine proteinase, assemblin
31 | c3mhsE_ |
| not modelled | 15.0 | 33 | PDB header:hydrolase/transcription regulator/protei Chain: E: PDB Molecule:saga-associated factor 73; PDBTitle: structure of the saga ubp8/sgf11/sus1/sgf73 dub module bound to2 ubiquitin aldehyde
32 | c3h9mA_ |
| not modelled | 14.8 | 21 | PDB header:lyase Chain: A: PDB Molecule:p-aminobenzoate synthetase, component i; PDBTitle: crystal structure of para-aminobenzoate synthetase,2 component i from cytophaga hutchinsonii
33 | d2p6ra2 |
| not modelled | 14.6 | 26 | Fold:Sec63 N-terminal domain-like Superfamily:Sec63 N-terminal domain-like Family:Achaeal helicase C-terminal domain
34 | d1afsa_ |
| not modelled | 14.4 | 28 | Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP)
35 | c2im5C_ |
| not modelled | 14.3 | 26 | PDB header:transferase Chain: C: PDB Molecule:nicotinate phosphoribosyltransferase; PDBTitle: crystal structure of nicotinate phosphoribosyltransferase2 from porphyromonas gingivalis
36 | d1at3a_ |
| not modelled | 14.0 | 19 | Fold:Herpes virus serine proteinase, assemblin Superfamily:Herpes virus serine proteinase, assemblin Family:Herpes virus serine proteinase, assemblin
37 | c2f6nA_ |
| not modelled | 13.7 | 21 | PDB header:transcription Chain: A: PDB Molecule:bromodomain phd finger transcription factor; PDBTitle: crystal structure of phd finger-linker-bromodomain fragment2 of human bptf in the free form
38 | d2g0ta1 |
| not modelled | 13.7 | 24 | Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nitrogenase iron protein-like
39 | d1us0a_ |
| not modelled | 13.3 | 38 | Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP)
40 | c2i6yA_ |
| not modelled | 13.3 | 10 | PDB header:lyase Chain: A: PDB Molecule:anthranilate synthase component i, putative; PDBTitle: structure and mechanism of mycobacterium tuberculosis salicylate2 synthase, mbti
41 | c2fqxA_ |
| not modelled | 13.3 | 22 | PDB header:transport protein Chain: A: PDB Molecule:membrane lipoprotein tmpc; PDBTitle: pnra from treponema pallidum complexed with guanosine
42 | c2f7fA_ |
| not modelled | 13.3 | 25 | PDB header:transferase Chain: A: PDB Molecule:nicotinate phosphoribosyltransferase, putative; PDBTitle: crystal structure of enterococcus faecalis putative nicotinate2 phosphoribosyltransferase, new york structural genomics consortium
43 | d2pbka1 |
| not modelled | 13.1 | 32 | Fold:Herpes virus serine proteinase, assemblin Superfamily:Herpes virus serine proteinase, assemblin Family:Herpes virus serine proteinase, assemblin
44 | d1ubdc2 |
| not modelled | 13.0 | 38 | Fold:beta-beta-alpha zinc fingers Superfamily:beta-beta-alpha zinc fingers Family:Classic zinc finger, C2H2
45 | c2l43A_ |
| not modelled | 12.7 | 19 | PDB header:transcription Chain: A: PDB Molecule:n-teminal domain from histone h3.3, linker, phd1 domain PDBTitle: structural basis for histone code recognition by brpf2-phd1 finger
46 | c2bs5A_ |
| not modelled | 12.5 | 47 | PDB header:sugar binding protein Chain: A: PDB Molecule:fucose-binding lectin protein; PDBTitle: lectin from ralstonia solanacearum complexed with 2-2 fucosyllactose
47 | d3efxd1 |
| not modelled | 12.4 | 43 | Fold:OB-fold Superfamily:Bacterial enterotoxins Family:Bacterial AB5 toxins, B-subunits
48 | d1vzva_ |
| not modelled | 12.4 | 21 | Fold:Herpes virus serine proteinase, assemblin Superfamily:Herpes virus serine proteinase, assemblin Family:Herpes virus serine proteinase, assemblin
49 | d1vqow1 |
| not modelled | 12.4 | 13 | Fold:Ribosomal protein L30p/L7e Superfamily:Ribosomal protein L30p/L7e Family:Ribosomal protein L30p/L7e
50 | c3bu8B_ |
| not modelled | 11.8 | 16 | PDB header:dna binding protein Chain: B: PDB Molecule:telomeric repeat-binding factor 2; PDBTitle: crystal structure of trf2 trfh domain and tin2 peptide2 complex
51 | d1qdla_ |
| not modelled | 11.6 | 18 | Fold:ADC synthase Superfamily:ADC synthase Family:ADC synthase
52 | d1x3ha2 |
| not modelled | 11.3 | 36 | Fold:Glucocorticoid receptor-like (DNA-binding domain) Superfamily:Glucocorticoid receptor-like (DNA-binding domain) Family:LIM domain
53 | c3pstA_ |
| not modelled | 11.1 | 17 | PDB header:nuclear protein Chain: A: PDB Molecule:protein doa1; PDBTitle: crystal structure of pul and pfu(mutate) domain
54 | d1xg8a_ |
| not modelled | 11.0 | 83 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:YuzD-like
55 | d2olua1 |
| not modelled | 10.9 | 10 | Fold:Lysozyme-like Superfamily:Lysozyme-like Family:PBP transglycosylase domain-like
56 | c3d6zA_ |
| not modelled | 10.6 | 33 | PDB header:transcription regulator/dna Chain: A: PDB Molecule:multidrug-efflux transporter 1 regulator; PDBTitle: crystal structure of r275e mutant of bmrr bound to dna and rhodamine
57 | c2euzA_ |
| not modelled | 10.6 | 50 | PDB header:cell cycle/dna Chain: A: PDB Molecule:ndt80 protein; PDBTitle: structure of a ndt80-dna complex (mse mutant mc5t)
58 | d1mnna_ |
| not modelled | 10.6 | 50 | Fold:Common fold of diphtheria toxin/transcription factors/cytochrome f Superfamily:p53-like transcription factors Family:DNA-binding domain from NDT80
59 | c3elfA_ |
| not modelled | 10.5 | 20 | PDB header:lyase Chain: A: PDB Molecule:fructose-bisphosphate aldolase; PDBTitle: structural characterization of tetrameric mycobacterium tuberculosis2 fructose 1,6-bisphosphate aldolase - substrate binding and catalysis3 mechanism of a class iia bacterial aldolase
60 | d1o6ea_ |
| not modelled | 10.0 | 29 | Fold:Herpes virus serine proteinase, assemblin Superfamily:Herpes virus serine proteinase, assemblin Family:Herpes virus serine proteinase, assemblin
61 | d3chbd_ |
| not modelled | 10.0 | 44 | Fold:OB-fold Superfamily:Bacterial enterotoxins Family:Bacterial AB5 toxins, B-subunits
62 | c3ln3A_ |
| not modelled | 10.0 | 39 | PDB header:oxidoreductase Chain: A: PDB Molecule:dihydrodiol dehydrogenase; PDBTitle: crystal structure of putative reductase (np_038806.2) from2 mus musculus at 1.18 a resolution
63 | c2krcA_ |
| not modelled | 9.6 | 43 | PDB header:transcription Chain: A: PDB Molecule:dna-directed rna polymerase subunit delta; PDBTitle: solution structure of the n-terminal domain of bacillus2 subtilis delta subunit of rna polymerase
64 | c2ysmA_ |
| not modelled | 9.5 | 23 | PDB header:transferase Chain: A: PDB Molecule:myeloid/lymphoid or mixed-lineage leukemia PDBTitle: solution structure of the first and second phd domain from2 myeloid/lymphoid or mixed-lineage leukemia protein 33 homolog
65 | c2w0tA_ |
| not modelled | 9.4 | 31 | PDB header:transcription Chain: A: PDB Molecule:lethal(3)malignant brain tumor-like 2 protein; PDBTitle: solution structure of the fcs zinc finger domain of human2 lmbl2
66 | c2l7pA_ |
| not modelled | 9.3 | 13 | PDB header:transferase Chain: A: PDB Molecule:histone-lysine n-methyltransferase ashh2; PDBTitle: ashh2 a cw domain
67 | c2a20A_ |
| not modelled | 9.3 | 26 | PDB header:metal binding protein Chain: A: PDB Molecule:regulating synaptic membrane exocytosis protein PDBTitle: solution structure of rim2 zinc finger domain
68 | c2e6rA_ |
| not modelled | 9.3 | 24 | PDB header:dna binding protein Chain: A: PDB Molecule:jumonji/arid domain-containing protein 1d; PDBTitle: solution structure of the phd domain in smcy protein
69 | d1npba_ |
| not modelled | 9.0 | 31 | Fold:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Superfamily:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Family:Antibiotic resistance proteins
70 | c3os6A_ |
| not modelled | 9.0 | 17 | PDB header:isomerase Chain: A: PDB Molecule:isochorismate synthase dhbc; PDBTitle: crystal structure of putative 2,3-dihydroxybenzoate-specific2 isochorismate synthase, dhbc from bacillus anthracis.
71 | d1olma1 |
| not modelled | 8.7 | 20 | Fold:RuvA C-terminal domain-like Superfamily:CRAL/TRIO N-terminal domain Family:CRAL/TRIO N-terminal domain
72 | d2af7a1 |
| not modelled | 8.6 | 16 | Fold:AhpD-like Superfamily:AhpD-like Family:CMD-like
73 | d1kjna_ |
| not modelled | 8.4 | 29 | Fold:Hypothetical protein MTH777 (MT0777) Superfamily:Hypothetical protein MTH777 (MT0777) Family:Hypothetical protein MTH777 (MT0777)
74 | d2h1ta1 |
| not modelled | 8.3 | 27 | Fold:Spiral beta-roll Superfamily:PA1994-like Family:PA1994-like
75 | d1c8aa2 |
| not modelled | 8.2 | 35 | Fold:beta-clip Superfamily:AFP III-like domain Family:AFP III-like domain
76 | d1l0nk_ |
| not modelled | 8.2 | 33 | Fold:Single transmembrane helix Superfamily:Subunit XI (6.4 kDa protein) of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) Family:Subunit XI (6.4 kDa protein) of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
77 | d1i8ta1 |
| not modelled | 8.0 | 31 | Fold:Nucleotide-binding domain Superfamily:Nucleotide-binding domain Family:UDP-galactopyranose mutase, N-terminal domain
78 | d2bv3a5 |
| not modelled | 7.9 | 17 | Fold:Ferredoxin-like Superfamily:EF-G C-terminal domain-like Family:EF-G/eEF-2 domains III and V
79 | c2wghA_ |
| not modelled | 7.9 | 24 | PDB header:oxidoreductase Chain: A: PDB Molecule:ribonucleoside-diphosphate reductase large PDBTitle: human ribonucleotide reductase r1 subunit (rrm1) in complex2 with datp and mg.
80 | d2ezla_ |
| not modelled | 7.8 | 36 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:Homeodomain-like Family:Recombinase DNA-binding domain
81 | c4a1cV_ |
| not modelled | 7.6 | 16 | PDB header:ribosome Chain: V: PDB Molecule:60s ribosomal protein l7; PDBTitle: t.thermophila 60s ribosomal subunit in complex with2 initiation factor 6. this file contains 5s rrna,3 5.8s rrna and proteins of molecule 4.
82 | c2zkr2_ |
| not modelled | 7.6 | 60 | PDB header:ribosomal protein/rna Chain: 2: PDB Molecule:60s ribosomal protein l37e; PDBTitle: structure of a mammalian ribosomal 60s subunit within an2 80s complex obtained by docking homology models of the rna3 and proteins into an 8.7 a cryo-em map
83 | d2fyuk1 |
| not modelled | 7.6 | 39 | Fold:Single transmembrane helix Superfamily:Subunit XI (6.4 kDa protein) of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) Family:Subunit XI (6.4 kDa protein) of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
84 | c2cvuA_ |
| not modelled | 7.6 | 32 | PDB header:oxidoreductase Chain: A: PDB Molecule:ribonucleoside-diphosphate reductase large chain PDBTitle: structures of yeast ribonucleotide reductase i
85 | c3p5rB_ |
| not modelled | 7.4 | 23 | PDB header:lyase Chain: B: PDB Molecule:taxadiene synthase; PDBTitle: crystal structure of taxadiene synthase from pacific yew (taxus2 brevifolia) in complex with mg2+ and 2-fluorogeranylgeranyl3 diphosphate
86 | c3r1rB_ |
| not modelled | 7.4 | 28 | PDB header:complex (oxidoreductase/peptide) Chain: B: PDB Molecule:ribonucleotide reductase r1 protein; PDBTitle: ribonucleotide reductase r1 protein with amppnp occupying2 the activity site from escherichia coli
87 | c3jueA_ |
| not modelled | 7.4 | 32 | PDB header:protein transport/endocytosis Chain: A: PDB Molecule:arfgap with coiled-coil, ank repeat and ph domain- PDBTitle: crystal structure of arfgap and ank repeat domain of acap1
88 | d2yt9a1 |
| not modelled | 7.3 | 63 | Fold:beta-beta-alpha zinc fingers Superfamily:beta-beta-alpha zinc fingers Family:Classic zinc finger, C2H2
89 | c1s1iY_ |
| not modelled | 7.2 | 80 | PDB header:ribosome Chain: Y: PDB Molecule:60s ribosomal protein l37-a; PDBTitle: structure of the ribosomal 80s-eef2-sordarin complex from2 yeast obtained by docking atomic models for rna and protein3 components into a 11.7 a cryo-em map. this file, 1s1i,4 contains 60s subunit. the 40s ribosomal subunit is in file5 1s1h.
90 | c3jywY_ |
| not modelled | 7.2 | 80 | PDB header:ribosome Chain: Y: PDB Molecule:60s ribosomal protein l37(a); PDBTitle: structure of the 60s proteins for eukaryotic ribosome based on cryo-em2 map of thermomyces lanuginosus ribosome at 8.9a resolution
91 | c2olvA_ |
| not modelled | 7.1 | 9 | PDB header:transferase Chain: A: PDB Molecule:penicillin-binding protein 2; PDBTitle: structural insight into the transglycosylation step of bacterial cell2 wall biosynthesis : donor ligand complex
92 | d1b8da_ |
| not modelled | 7.1 | 28 | Fold:Globin-like Superfamily:Globin-like Family:Phycocyanin-like phycobilisome proteins
93 | c3fehA_ |
| not modelled | 7.1 | 38 | PDB header:hydrolase activator Chain: A: PDB Molecule:centaurin-alpha-1; PDBTitle: crystal structure of full length centaurin alpha-1
94 | c3k7bA_ |
| not modelled | 7.0 | 36 | PDB header:viral protein Chain: A: PDB Molecule:protein a33; PDBTitle: the structure of the poxvirus a33 protein reveals a dimer of unique c-2 type lectin-like domains.
95 | d1xp3a1 |
| not modelled | 6.9 | 22 | Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Endonuclease IV
96 | d1mm2a_ |
| not modelled | 6.9 | 31 | Fold:FYVE/PHD zinc finger Superfamily:FYVE/PHD zinc finger Family:PHD domain
97 | d1bb8a_ |
| not modelled | 6.8 | 33 | Fold:DNA-binding domain Superfamily:DNA-binding domain Family:DNA-binding domain from tn916 integrase
98 | d1zina2 |
| not modelled | 6.8 | 71 | Fold:Rubredoxin-like Superfamily:Microbial and mitochondrial ADK, insert "zinc finger" domain Family:Microbial and mitochondrial ADK, insert "zinc finger" domain
99 | c1ybeA_ |
| not modelled | 6.7 | 23 | PDB header:transferase Chain: A: PDB Molecule:nicotinate phosphoribosyltransferase; PDBTitle: crystal structure of a nicotinate phosphoribosyltransferase

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0