Reference sequence (query): batch____ Identities normalised by aligned length. Colored by: property
HSP processing: ranked Search cycle: 3
1 [ . . . . : . . . . 1 . . . . : . . . . 2 . . . . : . . . . 3 . . . . : .] 361
batch____ bits E-value N 100.0% 1:361 MMKTMRIAAIPGDGIGKEVLPEGIRVLQAAAERWGFALSFEQMEWASCEYYSHHGKMMPDDWHEQLSRFDAIYFGAVGWPDTVPDHISLWGSLLKFRREFDQYVNLRPVRLFPGVPCPLAGKQPGDIDFYVVRENTEGEYSSLGGRVNEGTEHEVVIQESVFTRRGVDRILRYAFELAQSRPRKTLTSATKSNGLAISMPYWDERVEAMAENYPEIRWDKQHIDILCARFVMQPERFDVVVASNLFGDILSDLGPACTGTIGIAPSANLNPERTFPSLFEPVHGSAPDIYGKNIANPIATIWAGAMMLDFLGNGDERFQQAHNGILAAIEEVIAHGPKTPDMKGNATTPQVADAICKIILR
1 UniRef50_Q51945 Tartrate dehydrogenase/deca... 430 1e-119 1 76.5% 1:361 1:363 MPasFRIAAIPGDGIGLEVLPEGIRVLEAAALKHGLALEFDTFEWASCDYYLQHGKMMPDDWAEQLKQYDAIYFGAVDWPDKVPDHISLWGSLLKFRREFDQYVNIRPVRLFPGVPCALANRKVGDIDFVVVRENTEGEYSSLGGIMFENTENEIVIQESIFTRRGVDRILKYAFDLAEKRERKHVTSATKSNGMAISMPYWDKRTEAMAAHYPHVSWDKQHIDILCARFVLQPERFdvVVASNLFGDILSDLGPACAGTIGIAPSANLNPERNFPSLFEPVHGSAPDIFGKNIANPIAMIWSGALMLEFLGQGDERYQRAHDDMLNAIERVIADGSVTPDMGGTLSTQQVGAAISDTLAR
2 UniRef50_A3P147 Tartrate dehydrogenase n=59... 424 1e-117 1 70.8% 1:359 36:394 MSEkyRIAVIPGDGIGVEVMPEGLRALDAVSRRFGLRFAYEPIEWASCDYYAKHGQMMPDDWKTQLSGMDALLFGAVGWPETVPDHISLWGSLIKFRREFDQYVNLRPARLFDGVPCPLAGRKAGDIDFMIVRENTEGEYSAVGGTMFEGTEREFVVQQAVFTRHGTERVLKFAFELAQRRA-KRLTVATKSNGIAISMPWWDARAAEMAARYPDVAWDKQHIDILCARFVMQPDRFDVVVASNLFGDILSDLGPACTGTIGIAPSANLNPERNFPSLFEPVHGSAPDIAGKHIANPIAMIWSAAMMVDFLGAGTGPAREAHDAIVAAIEHVLKHGPRTRDMGGRASTREVGDAIVAHL--
3 UniRef50_Q46NL2 Tartrate dehydrogenase n=12... 408 1e-112 1 62.5% 3:359 5:356 --QQYKIAVIPGDGIGNEVVPEGIRVLEAASAKFGFKLAFTTYDW-SCARYHSQGSMMPSDGIERLRDSDAIFLGAVGFP-GVPDHVSLWNLLIPIRREFDQYVNLRPVRLLPGVPCPLANKKPGDIDFWIVRENTEGEYSQVGGRMFAGTEHEFVTQEAIFTRRGTDRIMRYAFDLAKKLGRNHVTSATKSNGIFHSMPFWDERFAAVGAEYPDIRTDQYHIDILAARFAMSPERFDVVVGSNLFGDILSDLGPGITGTIAVAPSANINPERKYPSMFEPVHGSAPDIAGQGIANPIGQIWSGAMMLEHLGQ-----PEAAAAIMQAIETVLtdRVHTPDLGGRASTQQMGAEIARAV--
4 UniRef50_P70787 Probable tartrate dehydroge... 405 1e-111 1 49.9% 2:360 1:353 -MREYKIAAIPADGIGPEVIAAGLQVLEALEKRSgfSIHTETFDW-GSDYYKKNGVMMPADGLEQLKKFDAIFFGAVGAPD-VPDHITLWGLRLPICQGFDQYANVRPTKVLPGITPPLRNCGPGDLDWVIVRENSEGEYSGHGGRAHKGLPEEVGTEVAIFTRVGVTRIMRYAFKLAQARPRKLLTVVTKSNAQRHGMVMWDEIAAEVSKEFPDVTWDKMLVDAMTVRMTLKPQSLDTIVATNLHADILSDLAGALAGSLGVAPTANIDPERRFPSMFEPIHGSAFDITGKGIANPVATFWTAAQMLEHLGEKD-----AATRLMSAVERVTEAGILTPDVGGTADTQQVTDAVCEAIA-
5 UniRef50_B8N3I6 Tartrate dehydrogenase, put... 402 1e-111 1 47.8% 4:361 46:396 ---TYRIASIPGDGIGIEVVDAAIQVVEKLAKTLgfNIDFTHIPW-GTAYYKEHGRYVSEDCLDTLRKFDAGLFGAVGAPD-VPDHISLWGLLLALRGPLQLYANVRPVRTFPGTKCPL-NTATEGIDWMLVRENSEGEYSGQGGRSHVGQPWEAATEVAMFTRVGIERIMRFAFEVAQSRPRKLLTVVTKSNSMRNGMVLWDQVAAEVAKDFPDVTWDKMLVDAMTVRMVAKPQSIDTIVGTNLHMDILSDLAAALAGSIGVAPSSNLDPTRKNPSIFEPVHGSAFDITGKGVANPVATFWSAAEMLSWLGE-----KEAAKQLMDCVEKVCAAGILTPDLGGTSNTQGVVDAVKKEIER
6 UniRef50_Q1IJA8 Isocitrate dehydrogenase (N... 398 1e-109 1 35.1% 4:359 2:332 ---TYKITLIPGDGIGPEVTSAAVRVLEA----TGLKFEWESF-AAGAEAYEKYKEYIPKELNESIERTRIGLKGPVTTPI----GGGFSSINVELRKRFELYANVRPIRNLPGV-----HTRYPGVDLVVVRENTEGLYSGIEHEVVPG----VVESLKIITEKASTRISKFAFNYARKMGRKKIHSIHKANIMKMSDGLFIRCSRNISKEYPEIIYGEHIVDNTCMQLVMNPYQYDILLLENLYGDIVSDLCAGLVGGLGLAPGANIGERA---SIFEAVHGSAPDIAGKNIANPTAVIRSGILMLRHLDEQD-----AANRVKAAVHHVYREGKhtRDMGGTTSTSEFADKVVEAI--
7 UniRef50_O29627 3-isopropylmalate dehydroge... 396 1e-109 1 35.2% 6:360 3:326 -----KIVVIPGDGIGKEVMEAAMLILEKL----DLPFEYSYYD-AGDEALEKYGKALPDETLEACRKSDAVLFGAAG--------ETAADVIVRLRRELGTFANVRPAKAIEGIECLY-----PGLDIVVVRENTECLYMGFEFGFG-----DVTEAIRVITREASERIARYAFELAKREGRKKVTALHKANVMKKTCGLFRDVCREVAKDYPEIQYNDYYIDAACMYLVMDPFRFDVIVTTNMFGDIVSDLAAGLVGGLGLAPSANVGER---TAIFEPVHGAAFDIAGKGIANPTAMILTACMMLRHFGYVEE-----AKKVEEAVEKTIKEGKKTPDLGGNLKTMEFANEVASLLD-
8 UniRef50_A9IDG2 Tartrate dehydrogenase n=5 ... 395 1e-108 1 49.2% 2:361 1:355 -MKTYRIATIPGDGIGKEVIPAGRQAMQVLAETDgfTFEFQDFDWGG-DYYRRHGVMMPADGLEPLRDKDAILFGSAGDPDIA-DHITLWGLRLKICQGLDQYANVRPTRLLPGIDGPLKRCTAEQLDWVIVRENSEGEYSGVGGRVHQGLPIEAATDVSMMTRAGVERILRYAFRLAQSRPRKQLTVVTKSNAQRHAMVMWDEIALEISREFPDVRWDKELVDAATARMVNRPASLDTIVATNLHADILSDLAAALAGSLGIAPTGNIDPERRGPSMFEPIHGSAFDIMGKGLANPIGTFWSVVMLLEHLGE-----HQAAARMMRAVESVTAdaLHTRDLGGTATTEQVTQAVCQHLRQ
9 UniRef50_C4Q3D3 Unc-13 (Munc13), putative n... 394 1e-108 1 29.2% 6:361 1978:2308 -----TVALIPGDGIGPEISAAVQEIFKFA----DVPIKWESVDVTPRPTEDGRFR-MPQSSLDIIRKHGIGLKGPLATPI----GKGHQSLNLALRKEFNLYANVRPCKSIEGYETPYKN-----VDLVTVRENTEGEYSGIEHVIVDG----VVQSIKLITEEASRRVARFAFQYAKDNGRRSVTAVHKANIMRMSDGLFLRVCREEAAHHREIEFCDMFLDTVCLNLVQDPTRFDVLVMPNLYGDILSDLAAGLIGGLGVTPSGNIGETG---AIFESVHGTAPDIAGQDRANPTALLFSAIMMLRYM-----NLNKHADLIESAVLATIRekYLTADLGGRSTCSQYTKEICRQIEQ
10 UniRef50_B3TCK6 Putative isocitrate/isoprop... 393 1e-108 1 29.8% 1:359 1:339 MSGKYNISLVTGDGIGPEISESALSILEAINDNFPLSLEIKKLE-AGDAVLKNTGKALPDETFEAIKNSDACLKAPVG--------ESAKDVIVYLRRMLDLYANIRPAKSYPNMPSL-----RDDVDLVIVRENTEDLYTGEEFDIG-----DAAVAFRIISEKASKRIANYAFTIASKRKMKKVTCVHKSNVMKKTDGLFARTCSKVANDFPDVKFEEMYVDACAMNLIRQPQLFDVIVTTNLFGDILSDESAQVVGGLGMAPAANIGDN---FGLFEPVHGAAFDIAGKQIANPTSFILSIKMMLDWLghNDQKCIEVGQKLEDVVYDIVKNNIKTKDIGGDKTTMEFTKEIISRL--
11 UniRef50_A4IK21 Tartrate dehydrogenase n=7 ... 393 1e-108 1 48.1% 2:361 1:354 -MREFRIAVLPGDGIGPEVMNEALKVLRILKDKDyfQFHADMFLWNS-EYYLQHGRMMPENGLDILKNYDAILFGAIGDPR-VPDDISVWELIMPIRKRFCQYVNLRPVKKLKGIPEQFIHQERP-INFVIVRENAEGEYSNSGGRIYQGTDQEIAVQNTIITRKGTERIARYAFQYAKKHGYQKVINATKSNAVVHSMKLWDEVIEHVASEYPDIQLEKYYIDALAAYFVQRPDTLQVIVASNLFGDILSDLGSALVGGLGISPSANINPEGVFPSMFEPVHGSAPDIAGKGKANPIAQIWSAALMLQSLGREDL-----ASIILKAIEKVTEHgkLTEDLGGNSTTAEMGEEIVRQIVK
12 UniRef50_Q55BI2 Isocitrate dehydrogenase [N... 393 1e-108 1 30.2% 2:359 21:348 -SKIQKVTLIPGDGIGPEISESVKRVFSAVKA----PIEWETVVV-------DANTGISKEVIESISKNKIGLKGPISTPI----GTGHQSLNLGLRKTFNLYANIRPCLSIPGHKT-----RYNNVNTVVVRENTEGEYSGIENQPVKG----VAQSIKIITKEASTRIAHYAFQYALANGRKKVTCIHKANIMKQSDGLFVKSCREVSTRYPSIKYEELTIDNNCMQLVLDPNQMDVMVLPNLYGDIVSDLCAGLIGGLGLTPSGNIGENGS--AIFEAVHGTAPDIAGKNKANPTALILSSIMMLRHLGHFHE-----ASIIENAVLNTLTEGKvtGDLGGNSSCSEYTDELVKKI--
13 UniRef50_P42958 Probable tartrate dehydroge... 386 1e-106 1 51.7% 2:361 3:353 -MKQFEIAAIPGDGVGKEVVAAAEKVLHTAAehGGLSFSFTAFPW-SCDYYLEHGKMMPEDGIHTLTQFEAVFLGAVGNPKLVPDHISLWGLLLKIRRELELSINMRPAKQMAGITSPLLH--PNDFDFVVIRENSEGEYSEVGGRIHRG-DDEIAIQNAVFTRKATERVMRFAFELAKKR-RSHVTSATKSNGIYHAMPFWDEVFQQTAADYSGIETSSQHIDALAAFFVTRPETFDVIVASNLFGDILTDISSSLMGSIGIAPSANINPSGKYPSMFEPVHGSAPDIAGQGLANPIGQIWTAKLMLDHFGEEEL-----GAKILDVMEQVTADGIKTRDIGGQSTTAEVTDEICSRLRK
14 UniRef50_Q4QLS3 3-isopropylmalate dehydroge... 386 1e-106 1 36.6% 2:359 1:358 -MQSYNVAVLAGDGIGPEVMAEAMKVLNKVQEKFGFKLNFNEFFVGG-AAIDHCGYPLPAETLKGCDEADAILFGSVGGPKwpPDQQPERGALLPLRKHFKLFCNLRPATLYKGLecPLRADIakGFDMVVVRELTGGIYFGQPKGREGEGSQTKAFDTEVYYKYEIERIARAAFEAAMKRN-KKVTSVDKANVLQSSI-LWRETVTEMAKDYPEVTLEHIYIDNATMQLIKAPESFDVLLCSNIFGDIISDEAAMITGSMGMLPSASLNE--AGFGLYEPAGGSAPDIAGKGIANPIAQILSAAMMLRY----SFNLNEAADAIESAVQKVLASGHRTADLAdpVSTAEMGTLITQAI--
15 UniRef50_P50213 Isocitrate dehydrogenase [N... 386 1e-106 1 30.1% 6:360 33:363 -----TVTLIPGDGIGPEISAAVMKIFDAAKA----PIQWEERNVTAIQGP-GGKWMIPSEAKESMDKNKMGLKGPLKTPIAA----GHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYT-----DVNIVTIRENTEGEYSGIEHVIVDG----VVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGA--NGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMG-----LFDHAARIEAACFATIKDGklTKDLGGNAKCSDFTEEICRRVK-
16 UniRef50_B1I496 3-isopropylmalate dehydroge... 385 1e-105 1 46.0% 1:359 13:364 MQKTYKIAVIPGDGTGPEQVREGLKVLHAAAGKEGFALETTVLDWGG-EYYLRTGEVLPPDAVEQLKRYDAIYLGAIGHPEVRPGIL-EKGILLRLRFELDQYINLRPVKLYPGVETPIAGKGPEDIDFVVVRENTEGLYAGSGGFLKRGTPDEVAIQTSINTRKGVERCVRFAFEYCRKrgRRKVTLCGKTNVLTFAFDLWERVFNEVGEEYPDIERDYAHVDAICMWMVKNPEWFDVIVTDNMFGDIITDLGAMLQGGMGIAAGGNLNPE--GVSMFEPIGGSAPKYTGKNVINPLAAVCAGAMMLEQLGETG-----AAARIEEAVKKVCAGHLKSLAAGRMggTDEVGDLVVSHL--
17 UniRef50_Q2JUI3 Isopropylmalate/isohomocitr... 385 1e-105 1 31.7% 5:360 3:355 ----YRVTLIPGDGIGPEVTRAMTTVLEA----SGVDLEWIRVE-AGVEVIEKYGTPLPPQVLESIRETRVAIKGPIGTP----VGTGFRSVNVAIRKELDLYANLRPAKSLPGIKSP-----FQDIDLVVVRENTEDLYAGIEFERGTPEaeGSAIGIKPISEFGSRRIVKFAFEYARQNGRKKVTAVHKANIMKFTDGLFLQVAREVAQEYPDIEFEDLIVDNMCLQLMQKPQLYDVLVLTNLYGDIISDLCAGMIGGLGVAPGANIGD---GIAVFEAIHGSAPKYAGQNKVNPSALILSGAMMLRYLGEREAAARVEAAV-----QSVIAEGkvTYDlgEPVGTQEMAEAIAARVQ-
18 UniRef50_O27441 3-isopropylmalate dehydroge... 385 1e-105 1 34.5% 2:360 1:328 -MKSMKIAVIPGDGIGVEVMEAALHILNTL----DLDLEFIHAD-AGDACLKRTGTALPEETLEAVGEARATLFGAAG--------ESAADVIVRLRREFDLFANLRPVKSLPGVPCLY-----PDLDFVIVRENTEDLYVGDE-----EYTPEGAVAKRIITRTASRRISQFAFQYAQKEGMQKVTAVHKANVLKKTDGIFRDEFYKVASEYPQMEATDYYVDATAMYLITQPQEFQTIVTTNLFGDILSDEAAGLIGGLGLAPSANIGEK---NALFEPVHGSAPQIAGKNIANPTAMILTTTLMLKHLNK-----KQEAQKIEKALQKTLAEGLVTPDLGGKLGTMEMAAEIARHLE-
19 UniRef50_Q58991 Homoisocitrate dehydrogenas... 385 1e-105 1 34.6% 1:361 1:342 MM---KVCVIEGDGIGKEVIPEAIKILNELGEFEIIKGE------AGLECLKKYGNALPEDTIEKAKEADIILFGAITSPK-PGEVKNYKSPIITLRKMFHLYANVRPINNFggKIADYEFLNAKNIDIVIIRENTEDLYVGRER-----LENDTAIAERVITRKGSERIIRFAFEYAIKNNRKKVSCIHKANVLRITDGLFLEVFNEIKKHY-NIEADDYLVDSTAMNLIKHPEKFDVIVTTNMFGDILSDEASALIGGLGLAPSANIGDDK---ALFEPVHGSAPDIAGKGIANPMASILSIAMLFDYIGEKEK-----GDLIREAVKYCLINKKVTPDLGGDLKTKDVGDEILNYIRK
20 UniRef50_Q6W109 Tartrate dehydrogenase n=13... 385 1e-105 1 50.1% 2:360 1:347 -MKSYSIALIPGDGIGQDVTDAAWQVLSTVARHSGFTLTATPFPW-SCAFYKETGAMMPPDGIETLRRFDAILLGAVGWPAEVPDSVSLHGLLLPIRKAFVQYANIRPHRLLSGVKGPLKA---EGFDILCIRENTEGEYSGAGGRVHQGTADEVAVETSIFTRTGVERILRFGFDQARQR-RRKLASVTKSNAQKYSMVLWDEITRELAAEYPDVEVTSYHIDAMAARMVMAPESLDVVVASNLFGDILTDLGAAIQGGLGFAASANINPDRSAPSMFEPVHGSAPDIAHLGIANPIAAIWSGAMMLDHLGQ-----ARAARKVIEALERTTARGIGTVP--GKNRTETITAAVLAALD-
21 UniRef50_D1HRU7 3-isopropylmalate dehydroge... 383 1e-105 1 34.0% 2:360 141:499 -PKRYSITLLPGDGIGPEVISVAKNVLKLAGSLEGIEFGFQEMPVGGC-ALDLTGVPLPEETLLVAKQSDAVLLGAIGGYKWdeKHLKPETGLLQLRSGLKVFANLRPASVLPQlaSTLKKEVAEGVDLMVVRELTGGIYFGKpgFSKNENGEEIGFNTEVYATYEIDRIARIAFETAQKR-RGKLCSVDKANVLEASM-LWRKRVTAMASEYPDVELSHMYVDNAAMQLVRNPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASVGES--GPGLFEPIHGSAPDIAGQDKANPLATVLSAAMLLRylGEGN-----AAKRIETAVLDTLDRGFRTRDiaGtvGCKEMGEQVLKAVE-
22 UniRef50_Q5SIJ1 Homoisocitrate dehydrogenas... 382 1e-104 1 37.4% 5:360 3:332 ----YRICLIEGDGIGHEVIPAARRVLEA----TGLPLEFVEAE-AGWETFERRGTSVPEETVEKILSCHATLFGAATSPTRKVP--GFFGAIRYLRRRLDLYANVRPAKSRP------VPGSRPGVDLVIVRENTEGLYVEQERRY-----LDVAIADAVISKKASERIGRAALRIAEGRPRKTLHIAHKANVLPLTQGLFLDTVKEVAKDFPLVNVQDIIVDNCAMQLVMRPERFDVIVTTNLLGDILSDLAAGLVGGLGLAPSGNIGD---TTAVFEPVHGSAPDIAGKGIANPTAAILSAAMMLDYLGE-----KEAAKRVEKAVDLVLERGPRTPDLGGDATTEAFTEAVVEALK-
23 UniRef50_B1MJY2 Tartrate dehydrogenase n=5 ... 380 1e-104 1 51.4% 1:358 1:348 MSDRMRVATIPGDGIGVDVTREAVKVMDSA---TGGRIEWTEFDY-SCERYAKTGAMMPPDAPTTLAGFDAILLGAVGYP-GVPDDVSLWGLLIPLRRAFNQYVNLRPVRLLPGIASPLAGVSDEALSMVIVRENTEGEYSPIGGVHNRGNQNEFALQESVFTRIGCERIIRYAFELAASAGF-RVCSATKSNGIIHSMPYWDSIFNEIAAEYPQTPSVSMHVDALAARMVSDPASLDVIVASNLFGDILSDLAAAITGGLGLAASGNINPERTAISMFESVHGSAPDIAGQGIANPVAQILAGAMLLDHLNE-----PATANKIRLAVDQVLSDgvRTPDLGGTATTEQLGTAIAEA---
24 UniRef50_B9KYU3 Isocitrate dehydrogenase (N... 378 1e-103 1 33.0% 7:361 23:358 ------VTLIPGDGIGPEIVESACRLIEAV----GAPIEWEVRRAGASVFREGIASGVPDDTIESIKRTRVVLKGPLETP----VGYGEKSANVTLRKLFEAFANVRPVRELPSVPTPYRG---RNIDLVVVRENIEDLYAAIEYRETPG----VTIAHKLISYKGSEKIIRFAFELARAEGRKKVTCATKSNILKLTEGWFQHIFEEIASEYPDIEANHLIIDNCAHQLVKAPEQFEVIVTTNLNGDIISDLASGLVGGLGFAASGNYGHE---VAIFEPVHGTAPKYAGKNVINPTAMILTAVMMLRYIDEFET-----AETIEQALIVTLEEGklTRDVVGdvSTTAFTDAIIANLGR
25 UniRef50_Q0D0R7 Isocitrate dehydrogenase su... 378 1e-103 1 30.6% 4:359 54:385 ---KYTVTLIEGDGIGPEISQSVKDIFSAA----NAPIKWEPVDVTPI--LKDGKTAIPDDAIESVRRNYVALKGPLATP----VGKGHVSLNLTLRRTFNLFANVRPCRSIAGYKTPY-----DNVDTVLIRENTEGEYSGIEHVVVDG----VVQSIKLITKEASERVLRFAFQYARSINKKKVRVVHKATIMKMSDGLFLNTAREIAKDFPDVEFDAELLDNSCLKIVTDPTPYnvLVMPNLYGDILSDMCAGLIGGLGLTPSGNIGDE---CSIFEAVHGSAPDIAGKGLANPTALLLSSIMMLQHMG-----LHEHAGRIQKAIFDTLAEGklTGDLGGKAKTSEYAEAIMKKL--
26 UniRef50_A5CDH3 Isocitrate dehydrogenase, N... 377 1e-103 1 30.6% 1:360 1:342 MKNVIPVTIAYGDGIGPEIMEAVVYVLKEAA----VPLRLETIEIGEKLYNKYYTYGITEDTWSQIFRTKALLKGPVTTPQ----GGGYKSLNVTLRKTLGLYANVRPSCSY----FPFVNTSAPEIDVVIIRENEEDLYAGIEY----HHTADTYESVKLISRSGSEKIIRFAFEYALKNNRKTISCFSKDNIMKFTDGIFHKTFNEIASQYSNIQVDHYLIDIGSARLISSPQKFDVIVTSNLYGDILSDIAAKISGSIGLAGSANIGKDY---AMFEAVHGSAPDIAGQNIANPSGLLNAAIMMLVHLG-----LTEHAAKIENALKKTIEDGIHTADIYNpvGTKEFAQAIINNLE-
27 UniRef50_C1XGT6 Homoisocitrate dehydrogenas... 376 1e-103 1 40.1% 1:359 1:335 MSKTYKICLIEGDGIGHEVIPAARLVLEA----TGLKFEFVEA-QAGWETFERIGTSVPEATLEAVTHTDATLFGAATSPTKKVP--GFFGAIRYMRRKLDLFANVRPAKHHP------VPGSRPGVDLIVVRENTEGLYVEQERSYLEG---EIAIADTVITRKASARIGEYAARLAASRPRKQLHVAHKANVLPMTQGLFMNTVLAEAARFPEVKTQDIIIDNCAMQLVRNPERFDVIVTTNLFGDIISDLTAGLVGGLGIAASGNIGIKH---AVFEPVHGSAPDIAGKGIANPAATILSGVMMLDHLGE-----HEAARRVEAAVDKVLQEGPRTPDLGGNATTLQFAEAVARSL--
28 UniRef50_UPI000150AB37 dehydrogenase, isocitrate/i... 376 1e-102 1 28.6% 3:359 303:634 --QNHKVVLFPGHGIGPEISQAVCDIFAAAK----VPIDWEHHEIYTKPINEA-GDLIKEESLNAVINYKWGLKGPFATPI----GKGYRSLNVTMRKKLNLFANVRPCRSLAGVKTPYSN-----VDLVTIRENTEGEYSGLEHAVVPG----VVENLKIISQPACENIARYAFEFARKNNRKKVVACHKAGVMKKGDGLFINTCKKISSEYPEIEYTEEQIDTVCMKLSKNPEVFDVMVMPNLYGDIVSDLCAGLIGGLGLTASGNISH---TCAVYEAVHGTAPDIAGLNKANPTALLLSGVMMLKAMG-----LQKEGFAIEEAVIKTLSEGklTGDLGGKATTTDYTKAVIGHI--
29 UniRef50_Q6GF15 3-isopropylmalate dehydroge... 375 1e-102 1 32.3% 4:359 2:346 ---TYNIVALPGDGIGPEILNGSLSLLEIISNKYNFNYQIEHHEFGGAS-IDTFGEPLTEKTLNACKRADAILLGAIGGPKWTDPNNRPEQGLLKLRKSLNLFANIRPTTVVKGASspLKAERVEGTDLVIVRELTSGIYFGEPRYFNNHE----ALDSLTYTREEIERIVHVAFKLAASR-RGKLTSVDKENVLASS-KLWRKVVNEVSQLYPEVTVNHLLVDACSMHLITNPKQFDVIVYENLFGDILSDEASVIPGSLGLSPSASFSND--GPRLYEPIHGSAPDIAGKNVANPFGMILSLAMCLR----ESLNQPDAADELEQHIYNMIEHGQTTADLGGKLNTTDIFEILSQKL--
30 UniRef50_Q2JYV7 Probable tartrate dehydroge... 375 1e-102 1 49.3% 2:360 1:347 -MKTYRIALLPGDGIGRDVTDAAWAVLEKTAGSGGFSLEATRYPW-SCDYYLENGSMMPADGIETLKSFDAILLGAVGWPRKVPDSVSLHGLLLPIRKAFVQYANIRPHRLLPGVQGPL---RSDGFDILCIRENTEGEYSGAGGRIHQGADNEVAIETAIFTRKGVERILRFGFEQARAR-RGKLASVTKSNAQKYSMVFWDEITHGLSAEYPDVEVTSYHIDAMAARMVMAPESLDVVAASNLFGDILTDLGAAIQGGLGFAASANINPDRSAPSMFEPVHGSAPDIAHLGIANPIAAIWSGAMMLEHLGET-----AAAEKVMDAIETTTARGV--GAIPGKDRTDAITASVLSALG-
31 UniRef50_Q5SIY4 3-isopropylmalate dehydroge... 374 1e-102 1 33.7% 5:360 1:345 ----MKVAVLPGDGIGPEVTEAALKVLRALDEAEGLGLAYEVFPFGG-AAIDAFGEPFPEPTRKGVEEAEAVLLGSVGGPKWdpRKIRPETGLLSLRKSQDLFANLRPAKVFPGLesPLKEEIARGVDVLIVRELTGGIYFGEP----RGMSEAEAWNTERYSKPEVERVARVAFEAARKR-RKHVVSVDKANVLEVGE-FWRKTVEEVGRGYPDVALEHQYVDAMAMHLVRSPARFDVVVTGNIFGDILSDLASVLPGSLGLLPSASLG---RGTPVFEPVHGSAPDIAGKGIANPTAAILSAAMMLEHA----FGLVELARKVEDAVAKALLETP-PPDLGGSAGTEAFTATVLRHLA-
32 UniRef50_Q9WZ26 3-isopropylmalate dehydroge... 374 1e-102 1 34.3% 5:360 1:351 ----MKIAVLPGDGIGPEVVREALKVLEVVEKKTGKTFEKVFGHIGG-DAIDRFGEPLPEETKKICLEADAIFLGSVGGPKWdpEKRPEIGGLLALRKMLNLYANIRPIKVYRSLvsPLKEKVIggVDLVTVRELSYGVYYGQP----RGLDEEKGFDTMIYDRKTVERIARTAFEIA-KNRRKKVTSVDKANVLYSSM-LWRKVVNEVAREYPDVELTHIYVDNAAMQLILKPSQFDVILTTNMFGDILSDESAALPGSLGLLPSASFGDKN----LYEPAGGSAPDIAGKNIANPIAQILSLAMMLEH----SFGMVEEARKIERAVELVIEEGYRTRDIakAVSTSQMGDLICKKLE-
33 UniRef50_Q47WG3 3-isopropylmalate dehydroge... 372 1e-101 1 34.4% 6:360 3:360 -----NIAILAGDGIGPEVMVEAKKVLNTVASKFDFEITTQDYDIGG-AAIDNHGNALPDSTMAGCIESDAILFGSVGGPKwpPTEQPERCALLGLRSHFDLFCNMRPATLQPALSSLssDISEQGFDVLVIRELTGDIYFGEPKGRRGEGEEETGFDSMFYSRREVKRISHLAFQAAQKRN-NKVTSVDKANVLATSQ-LWRQVVEEVAVEYPDVELEHLYVDNAAMQLVRDPNQFDVMLCPNLFGDILSDICAMITGSMGLLPSASLNSD--GFGMYEPAGGSAPDIAGLGVANPIAQILSAALMLRY----SLNQGAAAKAIEDAVSNALDNGVLTADlkNAKSTSEVGDYICKQIE-
34 UniRef50_P33197 Isocitrate dehydrogenase [N... 372 1e-101 1 32.1% 7:361 22:357 ------ITVIPGDGIGPECVEATLKVLEAAKA----PLAYEVREAGASVFRRGIASGVPQETIESIRKTRVVLKGPLETP----VGYGEKSANVTLRKLFETYANVRPVREFPNVPTPYAG---RGIDLVVVRENVEDLYAGIEHMQ----TPSVAQTLKLISWKGSEKIVRFAFELARAEGRKKVHCATKSNIMKLAEGTLKRAFEQVAQEYPDIEAVHIIVDNAAHQLVKRPEQFEVIVTTNMNGDILSDLTSGLIGGLGFAPSANIGNE---VAIFEAVHGSAPKYAGKNVINPTAVLLSAVMMLRYLEEF-----ATADLIENALLYTLEEgvLTGDVVGyaKTTEYTEAIIQNLGK
35 UniRef50_D2EFL9 3-isopropylmalate dehydroge... 372 1e-101 1 32.8% 3:359 4:339 --KKWRVAVIKGDGVGPDVINASLLVLDAVKKKFNLDIEYVPA-VAGLNTVEKYGTNLPKETLDTLKETDCVLKGPTTTPE---GANSLPSANVGIRKYFDLYADVRPNKTLPNVPS-----IKPNVDMVIVRENTEGMYSGLDFRVNQETT----IGIRVITRKACERIVKYAFKLAESR-KKHVTLVHKGNVLKVSDGMFKDIFYEEAKKHPDVKADDAHVDAITQWFIKQPEFYDVIVTENLFGDIISDEAAMVVGGIGTGASANIGDKY---AMFEPIHGSVPKYTGMDKVNPIGTIMSVKMMLDWMDY-----KEAGKAIEDAVYKVLEEgiLTYDLGGTAKCSEVGKEIASKV--
36 UniRef50_C9KJM9 3-isopropylmalate dehydroge... 371 1e-101 1 34.6% 4:359 2:355 ---SYKITVIPGDGIGKEITDSAVEVLEKVDEKFGLGLSYTYKDAGGTAY-DKFGTPLPDDTIEACKASDGVLFGAVGGDKWddPALRPEKAILGLRKNLGLYANLRPVKVADALvsPLKPELVKGVDLVIVRELIGGIYFGDKCESEQHNGAERAWDLENYSVPEVDRIAKLAFETAKLR-RGKVTSVDKANVLATSR-LWRRTVAKVAESYPDVELNNLYVDNCAMQLAIRPTQFDVIVTGNLFGDILSDEAAVVGGSIGMMPSASIG---TSTSLYEPIHGSAPDIAGKGIANPMGTILSAAMLLRYSLHEEAAAKAIEAAVDKA----LADGYRTPDLWkkANTEEITKVICERI--
37 UniRef50_D0DDG4 3-isopropylmalate dehydroge... 370 1e-101 1 55.6% 2:323 1:316 -MKTYNLALIPGDGIGVDVTDAAMEVLGAAA-KGRFAFDTTSFPW-SCEYYLEHGRMMPEDGIETLRGFDAIYLGAVGWPATVPDSVSLHGLLLPIRKAFNQYANIRPHRLLAGVEGPLKA---EGFDILCIRENTEGEYSGAGGRVHEGKGNEVAVETSVFTRAGVERILRFGFEQARSR-RGHLTSVTKSNAQKYSMVFWDEVTRELAAEYPDVTVSHMHIDAMAAKMVMAPQDLDVVVASNLFGDILTDLGAAIQGGLGFAASANINPDRSAPSMFEPVHGSAPDIAGKNIANPIAAIWSVAQMLDHLGEAEVSAAVLSA--------------------------------------
38 UniRef50_Q9FMT1 3-isopropylmalate dehydroge... 369 1e-101 1 33.0% 3:360 45:402 --KRYNIALLPGDGIGPEVISVAKNVLQKAGSLEGLEFDFKEMPVGG-AALDLVGVPLPEETFTAAKLSDAILLGAIGGYKWDkkHLRPEMALFYLRRDLKVFANLRPATVLPQlaSTLKKEVAEGVDMMIVRELTGGIYFGEPRGItnENGEEVGVSTEIYAAHEIDRIARVAFETARKR-RGKLCSVDKANVLDASI-LWRKRVTALASEYPDVELSHMYVDNAAMQLIRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLGES--GPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKY----GLGEEKAAKRIEDAVVDALNKGFRTGDIYSpvGCKEMGEEVLKSVE-
39 UniRef50_UPI0001C310FF Tartrate decarboxylase n=1 ... 369 1e-101 1 46.6% 5:356 1:340 ----MNVVLLPGDGVGPEVMAEARKALDALE----LGIAWTDVPW-GSAWWAEHGTMMPADAIDVLRGHDAILMGAVGDP-AVPDDEALWGLILKIRQELDLWVNVRPARLLEGIPGPLAGRAPHDVDMVFVRENSEGEYAGVGGRVHRGFGHDVAIESSVFTRRGCERVIRYAFGMASAR-KGVLVNATKSNASRFGFPFWDEIVAEVGAEFPGVVVDRMLVDALSARLIRDPGSVDVVVASNLFGDILTDIAAALQGGMGMAASANLSPGGGVPALFEPVHGSAPDIAGRGIANPVGAIWSAALMLEQLGAGEG-----SRRLMDALETVCRRGPRTRDVGGTATTAEVGDAVV-----
40 UniRef50_B0ER68 Tartrate dehydrogenase, put... 369 1e-101 1 44.7% 4:359 10:350 ---QHKIIVIPGDGIGVEVMSEAEKMFQSL----NLPIQRDYVDW-GIQHYLKTGKVVPIDYIDQVKQYDAILLGSLGDPRTLPDYVTLE-PLIQMRQQLDQFLCLRPAKHFPGIPTPLKKC---EIDILVVRENSEGEYSNIGGIFKSGTPDEFAIESAVHTRRGLERVIRYAFEASRKR-RNHVTLATKSNAMKYGMVLWDSVFEAIAMEYPDVTAEKYYMDALSAEIVKNPSKFDVIVGSNLFCDIISDLTVTVAGSMGIAPSANINPERTFPSLFEPVHGSALDIAGKGICDPIGTMRASSMMLEFLGYSEESV-----LIEEAIQSSILQKITTIDIGGTKTTNEVGNFIADYI--
41 UniRef50_A5US63 Homoisocitrate dehydrogenas... 368 1e-100 1 37.3% 3:359 4:359 --APYTILVIPGDGIGREVIPAAVAVLRA----TGLPFHFENAD-AGWECFQRQGEALPSATLTAARAADAILFGAVASPGY--PVAGYRSPIVRLRRELDLYANIRPV--FDDLPENGSNPRRRKVDLVVVRENTEDVYAGRERVEDDGAT---AIAERVITRRASARIMRVACDLARArpPGRVTVVHKANVLRETCGLFRSVALEVAQAYPDLQIDEMLVDTCALQLATRPERFDVIVTTNLFGDILSDVACAWGGGLGLAPSANLGERH---ALFEPVHGAAPDIAGKGIANPLAAIGCTALLLDHLAGRAPADLASaaRIQRAIRHVRAAGPHTPDLGGSAVTTDITNAVLSHM--
42 UniRef50_Q81G11 3-isopropylmalate dehydroge... 368 1e-100 1 33.0% 6:360 4:345 -----RIVCLAGDGVGPEVMESAKEVLHMVERLYGHHFHLQDEYFGGV-AIDLTGQPLPQRTLAACLASDAVLLGAVGGPRWDSAKERPEKGLLALRKGLGVFANVRPVTVESATAHLSPLKNADEIDFVVVRELTGGIYFSYPKER----TEEVATDTLTYHRHEIERIVSYAFQLANKR-KKKVTSIDKANVLESS-KLWRTVTEEVALRYPNVEVEHILVDAAAMELIRNPGRFDVIVTENLFGDILSDEASVLAGSLGMLPSASHAE--KGPSLYEPIHGSAPDIAGKNKANPIAMMRSVAMML----GQSFGLTREGYAIEEAVSAVLKSGKCTADIGGTETTTSFTKAVIQEME-
43 UniRef50_C3MI61 3-isopropylmalate dehydroge... 368 1e-100 1 33.6% 3:359 6:363 --DTLTIAVLPGDGIGREVMPACLELVNAATTMAGAPALAFQTHNAGAQYYAESGDALPASTLDACRKSDAILFGAMGWPDIRFPDGTEIIPQLDLRMELGLFAGVRPIRWFPGLPRVLTDPRAEQIDFVLVREQTEGLFYARGR--GEIRNDEEAYDTMQITRSGTQRVTEFAFDIARQRKRrnVTCVDKANVF-QSMAFFRKVFDEVADRHSDLTKDHAYVDALALNMVKKPWTFDVLVTENMFGDILSDLAAGLIGGMGMAPSADIGDKH---GLFQPAHGTAPDIAGKGCANPSAMFLSAAMMLDWLAAkqPTLADAARLMEGAVEHTLSTKLAIpeYGGNANCAEMTRSVISSL--
44 UniRef50_Q46FW0 3-isopropylmalate dehydroge... 367 1e-100 1 35.8% 5:359 1:326 ----MRLAVIEGDGIGREIIPAAVKVLDA------FGLEFEKVPllGYTRWERTGTAISNNDLETIKGCDAVLFGAITT----VPDPNYKSVLLTIRKELDLYANVRPVKPLPGITGV---TGRNDFDFIIVRENTEGLYSGIE-----EIGPELSWTKRVVTRKGSERIAEYACKLAKKR-KNKLTIVHKSNVLK-SDKLFLDVCRQTASA-NGVEYEDMLVDSMAYNLIMRPERYDIVVTTNLFGDILSDMCAALVGSLGLVPSANIGEKY---AFFEPVHGSAPDIAGKGIANPLAAILCVKMLLEWMGEPR------SQIIDEAIAYVLQKKIITPDLGGTASTMEVGNAVAEYV--
45 UniRef50_Q0W5L4 3-isopropylmalate dehydroge... 366 1e-100 1 43.1% 2:361 1:376 -MVSYKVPVIAGDGIGPEVIAEGRKVIAAAQEVYNFDVEWIDMPF-SADHYVKTGETISESSLKELSKYRAIFLGSIGDDRKVKPGVLEKGILLTMRFYYDQYVNLRPVKLMEGVETPLKGKTAADIDFYVVRENTEDFYVGIGGRSKKGTsdEIAYQLGVVSKEGAKRIIEYSFDLANSRPKKHLSSVDKANVLTDIYGFWREVFTDTAAKYPDVKTDFNYVDAVTMWFVKNPEFFDVVVSPNMFGDIITDLGAMIQGGLGLAPGGNINPE--GTSMFEPMGGSAPKYKGLNKVNPIATIWAGAMLLEHLGE-----KQAAAGIVDAIEQNLKekIRTYDLGGSAGTSDVGTDIARIVKQ
46 UniRef50_A9QPI0 Isocitrate/isopropylmalate ... 366 1e-100 1 29.4% 2:361 1:342 -MKKVPITVAYGDGIGPEIMDATLKVILEA----GAELEIEKIEIGFKVYSMGNPSGIEPSSWESLKRTKVFLKAPITTPQ----GGGFKSLNVTVRKALGLYANIRPCISY----APFIHTKHPGIDLVIIRENEEDLYGGIEHRQGV----DSFQALKIMTRQGTERIIRYAFEYARCYGRKKVSSFTKDNILKITDGMFHKVFEEVAKEYPQIEKEHWIIDIGSAKLADNPQSFDVLVLANLYGDILSDVAVQIAGSVGLGASANIGHEY---SMFEAIHGSAPRRAGQNVANPSGLLLAAVQMLIHIGQ-----NAVADRVYNAWLKTIEEGIHTYDIFrkVGTREFARHVIKNLGK
47 UniRef50_Q1RJU4 Isocitrate dehydrogenase [N... 366 1e-100 1 29.6% 1:361 1:343 MAEFTPITIAYGDGIGPEIMEAVLYILRKAEAR----IRLETIEVGEKLYVKHYSSGISEQSWESIERTGVILKAPITTPQ----GGGYKSLNVTIRKTLQLFANIRPSVSFY----PFTKTLHPNLNLTIIRENEEDLYAGIEYRQ----THNMYESVKLISRTGCEKIIRYAFEYAVKNNRKKVTCLSKDNIMKFSDGIFHKVFNEIAKEYPQINNEHYIIDIGTARLATKPEIFDVIVTSNLYGDIISDVAAEISGSVGLAGSANIGEHY---AMFEAVHGSAPDIAGQDIANPSGLLNAAIMMLVHIGQGD-----IATLIENAWKKTIEDGMHTADIYnkVGTKEFAEEVVKRLGQ
48 UniRef50_UPI0001B4F4BD putative isocitrate/isoprop... 365 2e-99 1 42.2% 3:360 6:354 --KVVRLAVIPGDGIGPEVVAATVPALRAALEADGHRLDVTSFDWGG-ERYLRQGAAMPPDAADLVKKTDAVLFGAVGRPD-VPEHELVWGLIIGLRQQLDLAVNLRPVRAFPGVPTKVRDT--DGVDLVIVRENTEGEYVGAGGVAHAGSGHDLGIEVAVHSRRAIERAAHQAFALAGRRS-GRLCLVTKSNAMRYGYPLWDRVVREVGEQYPGVELETVLVDAMAARMIQAPRSLDVLLASNLFGDILSDLAAVLAGGMGMAPSANVLPDAEVPGIYEPVHGSAPDIAGKGVANPVACLLSGAMLLEDLGHTD-----AARRVRDAVADTLRdrHHTADLGGNATTADVASAVLHTME-
49 UniRef50_C1F3J9 Isocitrate dehydrogenase n=... 365 2e-99 1 28.1% 3:361 20:358 --TPIPVTVAAGDGIGPEITAAVMSILSAA----GAHLDAEYVEVGEQVYLRGNTSGIPQEAWDSIARTRVMLKGPITTPQ----GGGYKSLNVTMRKTLGLYANVRPCRTYK----PIVTTRHPDMDVVIVRENEEDLYAGIEHRQ----TQDVAQCLKLITRSGSERIARYAFEYARQHGRSKITCMIKDNIMKLTDGLFHRVFDEVAREYPEIQAHSQIVDFGMANFVHRPEDYDVVLLPNLYGDILSDIAAQMTGSVGLGGSVNIG---SGGAIFEAIHGSAPDLA-RDVANPSGLLLAAVEMLRHL-----KLDSIAAKVMNAWLCTLEEGIHTVDIAgrAGTRRFTEAVIERLGR
50 UniRef50_P28241 Isocitrate dehydrogenase [N... 363 5e-99 1 28.7% 4:359 36:369 ---KYTVSFIEGDGIGPEISKSVKKIFSAA----NVPIEWESCDVSPI--FVNGLTTIPDPAVQSITKNLVALKGPLATPI----GKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTY-----ENVDLVLIRENTEGEYSGIEHIVCPG----VVQSIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYtvSVCPNLYGDILSDLNSGlaGSLGLTPSANIGHK---ISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMG-----LTNHADQIQNAVLSTIASGprTGDLAGTATTSSFTEAVIKRL--
51 UniRef50_Q47SB4 3-isopropylmalate dehydroge... 359 8e-98 1 45.5% 3:360 4:351 --RTVKLAVIPGDGIGPEVVAEGLKVLSAVAPRHGLTLDTTEYEL-GAQRWHATGEVLPDAVEEELRQHDAILLGAVGDPT-VPSGVLERGLLLRLRFNFSHYVNLRPVRLYPGVTTPLAGVAPEDIDMLVVREGTEGPYAGMGGVLRKGTPHEIATQDSVNTRLGVERVVRYAFAKAAERPCHKLTLVHKDNVLTYAGELWQRVVREVGAEYPQVEVDYLHVDAATMFFVTQPRRFDVVVTDNLFGDIITDLGAAVAGGIGLAASGNINPEGDFPSMFEPVHGSAPDIAGQGKADPTATILSVSLMLEHLGYADAAAQIDQAVAEDLQERAKNGGVR--------STTQIGDDIAQRVA-
52 UniRef50_Q2YL58 3-isopropylmalate dehydroge... 359 9e-98 1 31.4% 2:358 1:364 -MASRKLLLLPGDGIGPEAMAEVRKVIAFLNSDLNLGFETEEGLVGGCAY-DAHGQAISDADMEKALAADSVLFGAVGGPKWdpYEVRPEAGLLRLRKDMQLYANLRPAICYPALasSLKPEVIEGLDILILRELTGGVYFGEPKEidLGNGQKRGIDTQVYDTYEIERIADVAFELARTR-RNKVTSMEKRNVMKSGVLWNQGVTARHKEKHADVQLEHMLADAGGMQLVRWPKQFDVILTDNLFGDLLSDVAAMLTGSLGMLPSASLGatGKRKALYEPVHGSAPDIAGKGIANPIAMIASLAMCLRY----SFGLVAEADRLEAAIAGVLDDGIRTADIWskVGTTEMGDAILAK---
53 UniRef50_Q493R1 3-isopropylmalate dehydroge... 359 1e-97 1 32.5% 1:360 1:361 MNNNYHIAVLPGDGIGPETTRQVYKILNVIKKQFQINIVTTEHKIGG-DAINSEGTPFPKSTLKYCEQSNAILFGAVGGPQwkGSESPEQGALLALRKHFNLFANLRPIYLADELksPLnnMIPNGIDIIFVRELTGGIYFGQPKGRSGTGLNEYAFDTAVYHRFEIERIANIAFKLAQKR-RKRVSSIDKANVLHTSM-LWREVVSHLAKNYPDVELEHLYIDNASMQLINNPSKFDIILCPNLFGDILSDECAMISGSIGMLPSASINEH--NFGLYEPAGGSAPDIAEKNIANPIAHILSIALLFRY----SLKLDHIAIKIEKAVSQALMLGYRTIDIAKKhsTNEMGDIIAALIK-
54 UniRef50_Q5HMF8 3-isopropylmalate dehydroge... 359 1e-97 1 30.5% 4:351 2:338 ---SYKIVALPGDGIGPEILSGTLELLKLISEKYHFEYHLESHHFGGVS-IDYYGTPLTNETLQSCKNADAILLGAIGGPKWTDPNNRPEHGLLKLRKSLNLFANIRPTFVTKGAssPLKQDIVEGTDLVIVRELTSGIYFGEPSYVKKTE----ALDSLKYSSQEIERIVRIAFNLANRR-RKKLTSVDKENVL-SSSKLWRQIVNDVKKDYPEVEVNHMLVDACSMHLITQPTQFDVIVTENLFGDILSDEASVIPGSLGLSPSASFG--QTGTRLYEPIHGSAPDIANEDKANPFGMVLSLALCLR----ESLNQNDAANELESIVYSFIQSNKTTADLGGQYRTSEI----------
55 UniRef50_P40495 Homoisocitrate dehydrogenas... 358 1e-97 1 35.9% 3:359 22:371 --KSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFID-LYAGFQTFQETGKALPDETVKVLKecQGALFGAVQSPTTKV--EGYSSPIVALRREMGLFANVRPVKSVEG-------EKGKPIDMVIVRENTEDLYIKIEkyIDKATGTRVADATKRISEIATRRIATIALDIALKrgQATLTVTHKSNVLSQSDGLFREICKEVYekYGQIKYNEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE---IVIGEPCHGSAPDIAGKGIANPIATIRSTALMLEFLGH-----NEAAQDIYKAVDANLREgiKTPDLGGKASTQQVVDDVLSRL--
56 UniRef50_A5UMS5 3-isopropylmalate dehydroge... 358 2e-97 1 36.1% 3:359 9:336 --NKYQIAVIPGDGIGKEVMEATISVLDEL------DVDFDYIyiAGDECNEEHGTPLPQETIDIVRDSDACLFGAAG--------ETAADVIVKIRQEMKMFANLRPVKSYPNTKSL-----FENVDFMIVRENTEGLYIA----DQEEETEDGAIAKRVITREAEERIIDYAFQYAKDNNRTKVTAVHKANVLKKTDGLFKKIFYEVGEKYPDIDTEDFYVDATAMYLVTQPQEFQVVVTTNLFGDILSDEGAGLVGGLGLIPSANIGADG---ALFEPVHGSAPDIAGQQKANPIAMMLSAIMMLRYLGEND-----AADKFDAAILKVLSEGklTGDLGGSATTMEVAQAVKNAL--
57 UniRef50_P04173 3-isopropylmalate dehydroge... 357 3e-97 1 31.0% 1:361 1:361 MSAPKKIVVLPGDHVGQEITAEAIKVLKAISdrSNVKFDFENHLIGG-AAIDATGVPLPDEALEASKKADAVLLGAVGGPKWGTGSVRPEQGLLKIRKELQLYANLRPCNFASDslSPIKPQFAKGTDFVVVRELVGGIYFGKRKE---DDGDGVAWDSEQYTVPEVQRITRMAAFMALQhpPLPIWSLDKANVLASSRLWRKTVEETIKNEFPTLKVQHQLIDSAAMILVKNPTHLniIITSNMFGDIISDEASVIPGSLGLLPSASLadKNTAFGLYEPCHGSAPDL-PKNKVNPIATILSAAMML----KLSLNLPEEGKAIEDAVKKVLDAGIRTGDLGGSNSTTEVGDAVAEEVKK
58 UniRef50_D0J9Z6 3-isopropylmalate dehydroge... 357 4e-97 1 32.9% 2:360 1:351 -MKK-NIVVIEGDGIGPEVIKQAIKALNSIGNRFHHEFSYQNV-LAGAKAIETFGDPMPKETIDSCLKSDAVLFGSIGDPKYdpRGMRPEDGLLKLRKEMDLYCNIRPIVTYPGikSPIKERKLEGVNFVIYRELTGGIYFGKKGRSKNGKE---AYDYCVYSEKEIERIGEMSFKAARSRNR-KMTLVDKANVLETSR-LWREVIQKMALDYSDVDLEFLYIDNAAMQILINPRKFDVILTDNMFGDILSDEASILTSSLGLLPSASIGSKK---SLFEPIHGSYPQAKGKNIANPLGCILSVSMMLEYF-----EMPQEKNLLEEAVKSSIQEKICTPDirNSSSTEEVGDYIEKYIK-
59 UniRef50_D0RN50 Threo-isocitrate dehydrogen... 357 4e-97 1 31.1% 2:361 1:357 -MSNLKFLVLEGDGIGPEIAKASVDVLQAALKLYDLKVNLVYEEI-GFASLKKHKTTFRSEVLKIAEKCDGMILGTCSHNDYPPTEEGGLNPSGVIRKYFDLYANVRPAKNRLG-----KLERFpgIDCLVMRENTEGFYSDRNMFKGVGetPDVAISIRNITRKGSTRIAEIGFKYAMER-RKKLVAIHKANVLRYSDGLFLECARQVSKKYPEVEYKEQIVDSMSAMLIRDPSVFDVILATNLFGDNLSDAASEIAGGLGLAESINAGENY---CIAQAQHGSAPDIAGKNIANPVSLIGSTAMMLDWLGKknQQLKEIAQMIEDAIDKTIInkTRTSDIGGNLSTTDFTDVLISNLKK
60 UniRef50_Q0BQF4 Isocitrate dehydrogenase (N... 356 6e-97 1 31.7% 1:360 7:348 MSQTTKitLIPGDGIGPEIVESVVSVLDAL----GSPFEWDSQY-AGMAAIARVGDPLPRETIQSIHHNKLALKGPLTTPT----GGGYRSVNVQLRKEFELFANVRPALTL------IPGGRFENVDITLIRENLDGFYAAFEHYMPIGdpHAVAMCAGFNTRTGCHRIIRYAFEYAMQNGRKKVTLVHKANILKALTGIFLEAGKEIAKEYEgiAFEERIVDACAMQLVLDPGRFDVIVTTNLFGDILSDLIAGLIGGLGLAPGGNIG---KQAAIFEAVHGSAPDIAGKGIANPLALMLAAAMMLDHVGKTDL-----ATRLRNAIrtTLEDGIRTPDLGGTAKTRELTQALISRIG-
61 UniRef50_A6WAX5 3-isopropylmalate dehydroge... 356 8e-97 1 31.1% 2:361 21:376 -SKQYSLAVLHGDGIGPEIVPASVKILDAAVAAAGATPIAWTELPLGRSAIDEYGEHTPTKTLDALDEVDGWLLGPHDSAAYPEPYRSQLNPSGTIRKHFGLFANIRPAKAFRG-----GNAIVEGTDLVIVRENTEGFYADRNTFAGTGetPDVAIMHGIITRAATERIAHEAFQLARTRD-KRVTIVHKANVLKMTTGLFRDVCREVGKQYPDVAINDFHIDAATVHLVRRADKFDVIVTENMFGDILSDLAGEVAGSLGIAPSINSSATH---AMAQASHGSAPDIAGRDIANPIAMILSSAMLLRWLAAkdEKIARAADIVEAAVDLTVAEGATTPDMGGTSSCSGFADAVVAATAR
62 UniRef50_D2VFR4 Homo-isocitrate dehydrogena... 352 9e-96 1 34.0% 7:359 34:384 ------IGVIPADGIGKEVVPAAVQVMNAAIAkkQNDFSLQYIPlaGWETFQKTGKSLPVETVEALkkCDGAIFGSVQSPSHKV--EGYSSPIVAMRKLVDLYANIRPCQDL-----------AKGIDMLIVRENTECLYIKKEktVDPTTGEKTAVADRLITERASKRIAEIAYKLAVQRNKnkVTIVHKSNVLSVSDGLFRESCLEISKKYPQVKTEEQLVDSMVYKMILDPTQYDVVVAPNLYGDILSDAGSAFVGGLGVTASANLSDS---FALVEPVHGSAPDIFGKKISNPIATIRACAMLLRHLQEKDPklNEIADSMDRAVNVVMPDKTvtPDLGGKGNTETLVDAIIKNL--
63 UniRef50_O81796 Isocitrate dehydrogenase [N... 352 1e-95 1 27.8% 1:360 30:368 MPRprTVTLIPGDGIGPLVTGAVEQVMEAM----HAPVHFERYEVLGNMRK------VPEEVIESVKRNKVCLKGGLATP----VGGGVSSLNMQLRKELDIFASLVNCINVPGLVT-----RHENVDIVVIRENTEGEYSGLEHEVVPG----VVESLKVITKFCSERIARYAFEYAYLNNRKKVTAVHKANIMKLADGLFLESCREVAKHYSGITYNEIIVDNCCMQLVAKPEQFDVMVTPNLYGNLIANTAAGIAGGTGVMPGGNVGAEHAIFEQGASAGNVGNdmVEQKKANPVALLLSSAMMLRHL-----RFPTFADRLETAVKQVIKEGkrTKDLGGDCTTQEVVDAVIAALE-
64 UniRef50_P41564 Isocitrate dehydrogenase [N... 352 1e-95 1 28.3% 4:360 16:346 ---RHTVTMIPGDGIGPELMLHVKSVFRHAC----VPVDFEEVHVSSNADEEDIRNAI-----MAIRRNRVALKGNIETNHNLPP--SHKSRNNILRTSLDLYANVIHCKSLPGVVT-----RHKDIDILIVRENTEGEYSSLEHESVAG----VVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVY---AVFeaTRNTGKSIANKNIANPTATLLASCMMLDHL-----KLHSYATSIRKAVLASmnENMHTPDIGGQGTTSEAIQDIIRHIR-
65 UniRef50_Q12545 3-isopropylmalate dehydroge... 352 1e-95 1 31.4% 1:360 1:372 MTTTYKILVLPGDHIGPEIMAEAIKVLTTIETHRPNLHFNLTTDLVGGTSIDTHGVPITQSVLDAAKASDAVLFGSIGGPEWAGVHPTPESGLLQLRQHLDAFANLRPcfLVPSlaSPIREHVVKGTRFIVVRENCGGAYFGEKKEE-----EDVASDLWVYTRPEIERLARVSAAVARIMGRstVWSADKANVLASGRLWRRITSDIFAKEFPDITLQHQLADSMAMLMVRDPRRFnvIHTDNTFGDILSDISGAITGTLGLMPSASlgEGHRSNGIYEPVHGSAPDISGKGLANPVAQILSVAMMLRY----SMGLEKEATAVERAVVKVLDAkiRTGDLGGRATCSQVGDAVCEVLG-
66 UniRef50_Q4FP17 3-isopropylmalate dehydroge... 352 1e-95 1 29.9% 3:360 5:368 --KKRKILLLPGDGIGPEVIQEVKKVILWLNSNKSLDFEIDE-DLAGGCSYDKHGTPITDEVFYKALESEFVMLGAVGGPKWdeFSKKPERALLKLRKELKLFANLRPAICFEQlaSTLKPEIVSGLDIMIVRELTGGIYFGEPRGIKpeNGERKGINTHSYTTSEIVRVAKVAFDLARKRS-NRVTSCEKSNVMEAGQLWKEEVQELHDKEYKDVELSHMLADNCAMQLLKNPKQFDVIVTDNLFGDMLSDQASMLTGSLGLLPSASLGadGEMRAMYEPIHGSAPDIAGKEIANPIASILSFAMALRY----SLDLDSEADALEKAVQDVLNDGLRTKDikKEVSTSAMGDAIISKLQ-
67 UniRef50_Q7UTP0 3-isopropylmalate dehydroge... 351 2e-95 1 31.3% 1:361 1:355 MPQSFHLVILGGDGIGPEVCDQSVRLLEIMQPhdGVEFQLDRHSVGVGEY-QRSGEALPQSAYDACLASDAVLLGAMGLPNVRYPNGKEIAPQLDLRERLQLYGGVRPIRLYHEADTPLKGHGPGEIDFVLVRESTEGLFYGRDAIADLEADE--ATNLLRITRSASERVCRLAFETARRrgKKTVTLIDKANVL-SSMVYFRHVFDEVAKEFLDIKAEHVYVDAAALFLVRRPQDFDVMVTENMFGDILSDLAAGLVGGMGMAPSGDIGDDA---AVFQPSHGSAPDIAGQSIANPIAMHLSTAMMLEWLDHPETRRAADALNAAI--ADVLSdtQRTADMGGNLSTVEITDKIAERLSK
68 UniRef50_C6V444 Isocitrate dehydrogenase n=... 351 2e-95 1 27.2% 5:361 2:337 ----PKLTVAYGDGVGPEIMTSVLEIIFEA----GAEIQIDTIEIGQKIYEKGWPSGISDSGWETLKRNKVLLKAPITTPR----GGGVRSLNVTLRKKLGLFANIRPCKS-------HLEWQDPKMDIVIIRENEEDLYSGIEYRQTLDTYN----CTKVITESTSERICRYAFEYARSNGRKKVTVMVKDNIMKLTDGIFHKLFKKVALEYPDIESENYIIDIGAARIAKNPEKFDVIVTLNLYGDIISDIAAEISGSVGLGGSINIGEEY---AMFEAVHGSAPDIADQDIANPSGLLNAAMYMLSYIGQ-----KEIAQKVYSAWLKTLKSGVHTADIFNPlgTKKFTEHIIHNIDR
69 UniRef50_P51553 Isocitrate dehydrogenase [N... 351 3e-95 1 28.0% 4:360 54:384 ---RHTVTMIPGDGIGPELMLHVKSVFRHAC----VPVDFEEVHVSSNADEEDIRNAI-----MAIRRNRVALKGNIETNHNLPP--SHKSRNNILRTSLDLYANVIHCKSLPGVVT-----RHKDIDILIVRENTEGEYSSLEHESVAG----VVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVY---AVFeaTRNTGKSIANKNIANPTATLLASCMMLDHL-----KLHSYATSIRKAVLASmnENMHTPDIGGQGTTSEAIQDVIRHIR-
70 UniRef50_A7SJV9 Predicted protein n=1 Tax=N... 351 3e-95 1 26.7% 6:361 52:386 -----TVTLIPGDGIGPEMVVAVQDIFRHI----GVPVDFEELNLSGLD-IKDEDSYlfNEAITSIKRNGVAMKGNIFTPLDAIP--GFRSLNLELRVHLDLFANIVRCKSIPGIQT-----RHNNVDLVIIRQNTEGEYSHLEHENVSG----VIENLKVTTEEACMKIAQYAFDFAEKHDRKKVTAVHKANIMKMGDGLFLRCCEEMSHSYPNIEFNSMIIDNCCMQLVAHPQQFDVMVLPNLYGNIVSNIGASLVGGPGIVPGENIGGDY---AIFegSRHTGLDIQGKDISNPISMLFASTLMLEHL-----EFTAYADLINSAILKVVQRGVLTADVGGSHTTTQFLSALKSELDQ
71 UniRef50_Q2J3B4 3-isopropylmalate dehydroge... 348 2e-94 1 30.6% 2:360 1:366 -MATHKLLLLPGDGIGTEVMAEVSRLIDWLNKAGIASFETEHGLVGG-AAYDADKVAITDATMALAQASDAVIFGAVGGPKWdpYDARPEAGLLRLRKDLALFANLRPAVCYPALasSLKPEVVEGLDIMIVRELTGGVYFGEPKTidLGNGQKRAIDTQVYDTYEIERIGRVAFDLARKR-RNKVTSMEKRNVMKTGVLWNEVITQVHAREYKDVQLEHQLADSGGMNLVKWPKQFDVIVTDNLFGDMLSDIAAMLTGSLGMLPSASLGatGKRKAMYEPVHGSAPDIAGKGLANPVAMLASFGMALRY----SLDMGELADKLDEAIAVVLARGLRTADIKSevSTSQMGEAIVQEMQ-
72 UniRef50_O13696 Isocitrate dehydrogenase [N... 348 2e-94 1 28.3% 4:360 20:354 ---KYTVTLIPGDGIGRETSNAVTEIFKTA----NVPIEFEEIDVTGMenNKSSGDAL-HEAIQSLKRNKVGLKGILFTPFEKGGHTSF---NVALRKELDIYASLVLIKNIPGFKT-----RHDNVDFAIIRENTEGEYSGLEHQSVPG----VVESLKIITEYKSKRIAQFAFDFALQNGRKSVTCIHKANIMKLADGLFRRTFYDVANGYDAITPKDLIVDNASMQAVSRPQQFDVLVMPNLYGSILSNIGSALVGGPGVIPGANFGRDY---ALFEpcRHVGLSITGRGEANPTAAILSACLMLRHLG-----LKDYADLINAATYSVIEEGklTKDLGGSASTGDFTHAILERME-
73 UniRef50_Q2VZV2 3-isopropylmalate dehydroge... 347 3e-94 1 29.7% 2:361 1:366 -MAAKKLLILPGDGIGVEVMAQVRRIIDWMGRKRKIEFEITEGLLGG-AAYDVHGTPYPAETLEAALAADAVLLGAVGGPKWdpFDKKPERGLLGIRKDMGLFANLRPATVLEALasTLKAEVVSGLDIMILRELTGGLYFGQPRGIDtpDGTRKGYNTLVYTTPEIQRIGRVAFDLARKRN-KKLCSVDKANVLECTVLWREEMIKLQKEEFPDVELTHMYVDNAAMQLVRNPKQFDVMVTENMFGDILSDCAAMLTGSLGMLPSASLGeqGKRKALYEPVHGSAPDIAGKDMANPLATIMSFAMCLRY----SFDMAAEADLIETAVKNVLKGGLRTADikAKVSTTVMGEAVVRELDK
74 UniRef50_A8TPC9 3-isopropylmalate dehydroge... 347 5e-94 1 38.5% 5:360 13:371 ----YRIAVVPGDGIGPEVSAATVRVLTQALGTS-FPIEFRDYD-AGAECFRRTGTAFPEATQVACRQAHAVLHGAAGLPDVLFPDGTEAGqsMKIRAALDLYANVRPIRLMEGAPRRLVGKGPDDIRFTIVRENTEGLYAARGG--GNIIRGQIATDTLVMTREGVERIVRYAAELAraDGVRRVTIVDKANVLR-SYAFFREIADGVLADCPGIEVEHVIVDAMTVHMIERPEHFDVIVCENLFGDILSDLGAAIMGGMGLAPSGEIGRDHGY---FQGSHGSAPTIAGKGLANPIACILSGAMMLDWLghSDPALTRAAERIREATGAVLKAGrvTPDIGGSGSTESCAAEICATLG-
75 UniRef50_P34738 3-isopropylmalate dehydroge... 345 2e-93 1 31.9% 2:361 1:364 -MATHNIVVFGGDHCGPEVVLEAIKVLKAIETNSPSAGKFnqNHLLGGASIDKHNDPLTDEALNAAKAADAVLLGAIGGPEWgsSTVRPEQGLLKLRKELGTYGNLRPCNFASEssSPLKAEVCRGTDFIVVRELTGGIYFG---DRTEDDGSGYACDTEPYSRAEIVRIARLAGFLAlkNPPAKVWSLDKANVLATSRLWRKTVTDVISKEFPQLQLEHQLIDSAAMLLVKNPRALnvVITSNLFGDIISDEASVIPGSIGLLPSASLGgkGKCNGIYEPIHGSAPDISGKGIVNPVGTILSVAMMLRY----SLNLPKEADAVEAAVKAAIDNGTKTKDLGGNATTSDMGNAVVAELEK
76 UniRef50_Q2K2V0 3-isopropylmalate dehydroge... 345 2e-93 1 30.0% 2:358 1:364 -MTARNLFLLPGDGIGPEAMGEVRKIIAYMNEAMDAGFVTDEGLVGGCAY-DAHGAAISEADMQKALAADAVLFGAVGGPKWdpYEVRPEAGLLRLRKDLQLFANLRPAICYPALAssLKPELVEGLDILIIRELTGGVYFGEPKEidLGNGQKRGIDTQVYDTYEIERIAGVAFEMARTRQ-NRVCSMEKRNVMKSGVLWNQVVTETHKAKYSDVQLEHMLADAGGMQLVRQPKQFDVIVTDNLFGDMLSDVAAMLTGSLGMLPSASLGatGKRKALYEPVHGSAPDIAGKGIANPIAMIASFAMCLRY----SFNMVKEADDLEKAIANVLDKGIRTGDicRQVGTVEMGEAILAE---
77 UniRef50_B0RIP4 3-isopropylmalate dehydroge... 345 2e-93 1 40.9% 1:359 1:351 MPRTISLAVVPGDGIGPEVVHEALRVLREAVP-ADVSLDTTQYPF-GAGHFLETGQILTDSDLAALAQHDAILLGAVGGDPRDARLAgeRGLLLKLRFAFDHYINLRPTALLPGVASPLAA--PGQVDFVVVREGTEGPYAGNGGVLRRGTEHEIATEVSVNTAHGVERTVRFAFELAEKRDRKRVTLVHKTNVLTFAGSLWQRTVDRVAAEHPDVTVDYLHVDATMIFLVTDPSRFDVIVSDNLFGDIITDLAAAISGGIGLAASGNVNPTGAFPSMFEPVHGSAPDIAGQQKADPTAAILSVALLLDHLGLSEAAARVSAAVSDDLAARA------TGD-AAPRSTAEVGDAILRAL--
78 UniRef50_Q5P9Q1 Isocitrate dehydrogenase n=... 344 2e-93 1 28.9% 1:360 6:345 MSVPITVAY--GDGVGPEIMEAVLFILKEARA----DVSIETVDIGHNQYKKEWTSGIAPSAWESISRTRLLLKAPTMTPQ----GSGHKSLNVALRQRLGLYVNVRPCVSY----FPVVGTKHPDLDVVIIRENEEDTYSGVEHKLSEDTHECV----KISTRSASEKICAYAFNYARAHNRKKVTCFVKDNIMKMTDGILHASFDKVAKGYPDIEANYYIVDVGMAKIASNPEDFDVVVTTNLYGDIVSDIVSLSSGSIGLTGSANIGDYY---AMFEAVHGSAPDIAGKNVANPSGLLNAAVQMLVHIGQLDK-----AGVIRNAFLKTLEDGVHTADIyrRASTMEFAQAIVGNLG-
79 UniRef50_Q2RV53 3-isopropylmalate dehydroge... 344 2e-93 1 31.3% 1:361 1:367 MPVSKKILFLAGDGIGPEVMAQVRRVMDWLNQTGRTAFEVEDALVGG-AAYDAQGTPLHDDTVALALAADAVLLGAVGGPKWdpFELKPERGLLRLRKDLELFANLRPAMVFDALasTLKTELVSGLDVMIVRELTGGVYFGQPRGISapNGERRGVNTQVYDTHEIVRVAKVAFDLAGKRG-KRLCSVEKANVME-SGLLWREEVTKLGADYPEIALSHMYADNCAMQLVRQPKQFDVIVTDNLFGDILSDCAAMLTGSLGMLPSASLgaAGNRRAMYEPVHGSAPDIAGQDKANPLATILSFSMMLRY----SFDLAEEADLVDNAVRGVLAKGLRTGDigKTlgTTGMGDALLAEMAQ
80 UniRef50_Q1ARE1 3-isopropylmalate dehydroge... 344 4e-93 1 36.2% 1:348 1:337 MSQRFRVLLLPGDGIGPEVVAAARRVADAAAARFGLTLEYEERRI-GAAAIREEGAPVSKETLRRAGEADAVLLGAVGDPEFDGGEVRPEAGLLALRRELGTFANLRPVAAIPALssPLRPGVAEGVDLLIVRELTGGAYFGEK-----EEGEERASDLSVYTRGEVERVARVAFEAARGR-RGRVASVDKANVLATSR-LWRRVVGEVARDYPDVALEHVLVDAAAMHLVTDPGRFDVILTENLFGDILSDEAAVLPGSMGMLPSASLGEPGS-PGIFEPVHGSAPDIAGKGVANPYAAILSAAMMFRH----GLGRPEAAEAIERGVEAAVAAGCLTPDLGGSSGT-------------
81 UniRef50_C4QCG1 Isocitrate dehydrogenase [N... 343 4e-93 1 26.6% 4:360 68:394 ---RHTVAMLLGDGVGPELLSYVKEVFQVI----GAPIDFEEV-----AVNQESEDATFTDALLAMKRNGVGIKGNFAT------EPGQSSRNVALRLNLNLYAFVQRCRNFPGVVT-----RHQNVDIVIIRENTEGEYSRLEHENVPG----VVESLKIITREKSTRIAQFAFDYAVRHNRKKVTAVHKANIMKLGDGLFLDVCSSIAKNYPQIEFNHMIIDNTCMQLVTKPQQFDVIVLPNLYGNIVGNVAAGLVGGAGLTTGINLGPQ---NALFegTRNSGRSLAGKNIANPCGMLLTSADMLEYLGHI-----KEAKLIRDSVVDVieQKIRTADLGGSFKTSKVIEAVLKSLR-
82 UniRef50_C7RJH9 3-isopropylmalate dehydroge... 343 4e-93 1 31.0% 4:361 6:363 ---RFHIAVLPGDGIGPEIVASSLHVLEVLNERMGGIGFDFWHLEGGAAHYQKTGTAFSDENMAACKKADAVLLGAIGLPHVRYSDGTEVTTQLDLRVEMDLYAGLRPIRSYPSLPRVLVDKRASQIDLVLVREQTEGiyS---RCRGTIEDDRVAWETMMISRNGTSRVSEFAFRVAERRAkgKVLCVDRSNAL-TSMAFFRRIFGEVAERHPSVSADYAYVDTTAMKLVKSPWEFDVLVTENAFGGILSDLAAGVVGSLGLAPSADIGEKH---AVFQPAHGSAPHIAGQGLANPVAQILSVALMLDWLahGEPRLAHGARILEHAVEKALTV-VCPVEFGGKDGTAAITKAIIAQIRK
83 UniRef50_O59930 3-isopropylmalate dehydroge... 341 2e-92 1 29.2% 1:360 1:377 MSKrfKIVILPGDGIGPEVVAEATRVLEVvaSSSDVEIKLETHDFGGCS-IDKHGEPLTAATLEACKLADAILLGAIGGPKWGvsKVRPEQALLALRKALGLYANIRPANFASDSlsPLKPSVARGVDIIVIRELIGGAYFGERKELGARAQEDAAWDTMIYSVPEVQRITRSRRQVASPDPPLPVHSIDKANVLASSRLWRKVATETIQNEFPQLKLDHHLVDSASMLIVANPKKLnvILTENLFGDILSDESSVIPGSLGLLPSASLAARPLWprVYEPIHGSAPDIAGQGIANPIGTILSAAM----LCGTRSVWRSPAKAIEAAVEGarREGLRTADLGGSSKTKDIGHKVVEILK-
84 UniRef50_A9FME3 3-isopropylmalate dehydroge... 341 3e-92 1 34.9% 17:360 19:357 ----------------PSVIAEAKLLLELYQERAGLPIDLWELDL-GADRYLRDGTTFPNQIQIAirECSAVLLGALGDPR-VPNLEHARDILFGMRFGYDLYANVRPVRALSDRLVPLKGRTAKDIDFVVFRENTEGIYVGMGGQFKRGTPDEVAINEDVNTRKGVERIIRAAFDYARANGRTRVTMADKSNAMRHAHELWLRVFHEVRAQYPEIQSNHVYVDALCLYVIQDPGQFQVIVTNNLFGDIVTDLGAALQGGLGMAASANVHadPARVALFEPVHGSAPPLAGKDIANPFAAMLTAGLLLAHLG-----WPEEERRIERWVSQALDQGMCTVDVGGTLGTRAAGAWVREQIA-
85 UniRef50_D0LNY3 3-isopropylmalate dehydroge... 341 3e-92 1 33.6% 3:344 8:368 --DSYQVVLLPGDGIGPEVMAQARDLLEAVAEPSGVRFELDEIPCGGRFYLEHGARDWPEDAEARCRGADVILLGAVGWPSPDGPGpaGHSAVIGNRVDLDLYANVRPVKLLPGVAHRISgwRPEHVDMVILRENTEGLYAGMGGQLRVGGSASVATDTRLITRRGCERIIRRAFELCEQRGrkRVTGIVKHNVLE-GCKLFAEVFAEVASEYPDIANELAIVDAFTQWLVTQPEHYDVCVTTNLFGDIVTDLASVLQGGMGMAVGCNVGDEH---AMFEPIHGSAPPLAGKDEANPMAMLLATGEALAWLGQrdPRLRAIAHAVERAVATVAERgpLTVDLVG-----------------
86 UniRef50_Q5LAB4 3-isopropylmalate dehydroge... 340 5e-92 1 30.8% 5:361 3:352 ----FKIAVLAGDGIGPEISVQGVEVMSAVCEKFGHKVNYEYA-ICGADAIDKVGDPFPEETYRVCKNADAVLFSAVGDPKFDNDPtrPEQGLLAMRKKLGLFANIRPVQTFKClkSPLRAELVEGADFLCIRELTGGMYFGEKYQ-----DNDKAYDTNMYTRPEIERILKVGFEYAMKR-RKHLTVVDKANVLASSR-LWRQIAQEMAPQYPEVTTDYMFVDNAAMKMIQEPKFFDVMVTENTFGDILTDEGSVISGSMGLLPSASTGES---TPVFEPIHGSWPQAKGLNIANPLAQILSVAMLFEYF-----DCKAEGALIRKAVDASLDANVRTPEigEKFGTKEVGAWIVDYIRK
87 UniRef50_B3RY01 Putative uncharacterized pr... 340 5e-92 1 28.6% 4:360 87:413 ---RYTVTLIPGDGIGPEMARHVKTVLH----KCGAPIDFEVIDI--------KDESSTDAAIISLKRNGIGLKGTITTNISNPQSQ---SINAQIRRKLDLYSNIVPCKSIPGV-----WTRHGQVDLVVIRENTEGEYGSLEHENVDG----VVESLKIITEKKSRRIAKFAFDYALQNNRRKVTAIHKANIMKLADGLFLETCREISKDYTDIEFESMIIDNCCMQMVTNPQQFDVMVMPNLYGNIVSHIGIGLVGGIGLVPGKNIGDKY---AIFegARNIGSDLVGLNRANPCGFLFTSALMLRHLG-----LDDYADIIESAVRTTIKNGkrTPDIQGDRTTADFIDAVIKEID-
88 UniRef50_B1L5I7 Isocitrate dehydrogenase (N... 339 8e-92 1 30.9% 5:360 1:330 ----MRIAVIKGDGVGPEIMGATLSLLERYIGADFIEIK------AGKSYFIEEGKPIEDNAIEKIRECDSLLKGPVATPTKGPSYP---SVNTLLRREFKLYANVRPFRSYEGIS-------IRRIDTILVRENLECLYYGWEVE-----DEDRAIAMRVITKRGAERISEFAFNLAKREGRGRVTAIHKRNILKRTDGLFLDAFYRVASKF-DLRADDEIVDAAGYKLVKLDNAFDVMLTPNLYGDILSDVAAGVVGSIGLCGSAQIGED---FAAFEPIHGTGEDIAGKGVANPIGMIIAASMMLDWLWERG-RSPKRGEKIREAVDSVIRDRILTPDLGGDFRTEQVVEKIVDRLR-
89 UniRef50_P28834 Isocitrate dehydrogenase [N... 339 1e-91 1 27.0% 4:359 28:357 ---RFTVTLIPGDGVGKEITDSVRTIFEA----ENIPIDWETINIKQTDHKEGV-----YEAVESLKRNKIGLKGLWHTPA---DQTGHGSLNVALRKQLDIYANVALFKSLKGVKT-----RIPDIDLIVIRENTEGEFSGLEHESVPG----VVESLKVMTRPKTERIARFAFDFAKKYNRKSVTAVHKANIMKLGDGLFRNIITEIgkEYPDIDVSSIIVDNASMQAVAKPHQFDVLVTPSMYGTILGNIGAALIGGPGLVAGANFGRDY---AVFEpsRHVGLDIKGQNVANPTAMILSSTLMLNHLG-----LNEYATRISKAVHETIAEGKhtRDIGGSSSTTDFTNEIINKL--
90 UniRef50_A5FXZ9 3-isopropylmalate dehydroge... 337 4e-91 1 33.5% 5:359 1:350 ----MKIGILNGDDIGHEIVPEAVRVMQAAAARTGLAIEWQDIPI-GRAALDSLGSTLPDGTIERLDALDGWLLGPIGH-MAYPKIPEAINPHPLLRKHFDLFANIRPVKSHAALPCL-----HQGVDLVIVRENNEGFQPDRNVVAGSGetPDVTISVRVITRNGSSKVARAAFELARAR-RRHLTAVHKDTVFKLGCGMFAEECRRLAAEYPDVTYDEAIVDTFAMRLVMTPQRYDVVVTTNMFGDILTDEAAGLVGGLGMAAGLCAGPRH---AMAQATHGSAPDIAGRGIANPYAMIMSGQMLLDWLGRRhpAATAAARLIEQAVANMIEERrlTPDLGGQGTTAGMGSAIIEAM--
91 UniRef50_Q9U6V3 Isocitrate dehydrogenase ga... 337 5e-91 1 25.8% 4:360 44:376 ---RHTVTLLPGDGIGPEMLDIVQKIFTFA----NVPVDFEECQLDSKPTSPESDL---DNAIMSIQRNGVAIKGNIETKYDDP---IFKSRNVELRRRLDLFANVLHCVSIPTIPT-----RHKGINIVMIRENTEGEYSGHEHETVNG----VVESLKICTREKLERISRFAFDYAIAHNRKKITAVHKANIQKLADGLFLKVVGEIakEYPSITFDSMIVDNASMQLVSRPQQFDIMLMPNLYGNIISNIACGLVGGPGLVSGMNIGDKY---AVFegTRNTGSGIAGQDIANPTAFIRAGVDMLHYLG-----LTEYANLISDALFDAiiKRLHTKDIGGTAKTSDVVNAVMRNIE-
92 UniRef50_D2RVT1 Isocitrate dehydrogenase, N... 336 5e-91 1 29.2% 2:361 28:423 -PDNPIIPIIHGDGIGKDVGPAAQKVLEAAAEATGRDISWMRVY-AGESAREEYGEdlPDETVDAIREHRVAIKGPLTTP----VGAGFRSLNVALRQTLDLYANVRPTYYLDGVPSPMKA--PEEMDMVTFRENTEDVYAGIEWEAGTDEVEQvgIGLKPITEKGSKRLVREAIDYALEHDRDKVTLVHKGNIMKFTEGQFGDWGMEVaeEYPdvMVEERLADAMLQWMQLRTDEFDILAMPNLNGDYLSDAAGAQIGGLGIAPGGNFG---KGRMLAEPVHGSAPKRAGQDMANPTAMILSGRLMFDYLG-----WDDAADLIRDAVEETISSGKVTYDLErkLGTSEYTDEIVDTIEK
93 UniRef50_B7PN53 Isocitrate dehydrogenase, p... 336 6e-91 1 26.0% 4:361 47:378 ---RFFVTLLPGHGIGPEMMRHV----EAIFACGKVPVDFETIIV---DANVGDASSM-DHAIKSIRRNGVALKGNIETTSY---SMTVEPRNLLLRNKLELYVNVVHCRNHPGI-----NTKHKGVDIVVIRQNTEGEYSCLEHEVTSG----VVESLKIITWAKSFQIAKYCFEYARTHMRKKVTVVHKANIMKLTDGLFLKTCTEVAQEYPDIELNDIIIDNCCMQLVANPAQFDVMLVPNLYGNIVVNVACGLVGGAGVTSGRNYGKEY---AVFeaTRNTGTPLVGKNLANPVATLYAAVDMLKHL-----ELWDHAVVIRRAIEKTvrDKVHTKDLGGDATTSKVVENILKEVQK
94 UniRef50_UPI0001AF2578 isocitrate dehydrogenase [N... 336 8e-91 1 29.5% 2:360 1:367 -MRTYEVTLVPGDGSGPELVDAARSVLDHAARLSGFKIDWD-VHQAGQRALAESESLLPDATLNSIRTNGAALKGPTTTPI----GTGHRSVNITIRQELDLYACLRPVRSLP-IASTQEEPERPHVDLVVVRENTEDVYAGLegALGRPLPADTAVSLKPFTPHGCERVVEFAFNHAARHGRKLVESVCDARRYPATEGMFARVASKVAARHPSIASRTVPVPALCADLVRAPGRHDVLVLPNLYGDIISDVTAALVGSLGVAPGANIGAHH---AVFEATHGSAPEFAGSGRLNPTALIFSGCMLLDHLGEHET-----AARIRAAVEDVVAAgvLTFDlaDAATTVEFTRAVTDRLG-
95 UniRef50_B1L3C1 3-isopropylmalate dehydroge... 335 2e-90 1 32.9% 5:360 2:326 ----PRIAVIPGDGVGPEIIDAVIPVLETLSDLMNLPLDLRFFE-AGDETKRKRGVALPEETLNGVMNSDATLMVAIG--------ESAREVILPLRQKLDLYVNLRPAKSYP------VPRAIPGFDLTIVRENTEDLYVMSGWR-----GLDTAVDLRIITRRASERICRFGYRYARERGKSRVYVVHKANVLGGCM-LFREVCSRVAEE-EGFDYREMYVDSAAMRIAMD-RPFDVIITTNMFGDILSDLAAAFIGGLGMYPSANIGESR---AIFEPVHGTAPEIAGKNIANPMATILSAAMMMGWLGHEGG-----SKLIEEAVRRACELGYTTPDVGGSMRTKEVGLKISEIMR-
96 UniRef50_Q0X0C1 Putative dehydrogenase n=2 ... 335 2e-90 1 35.1% 6:361 21:361 -----TIAVIPGDGIGPEVIEPALDVLDAL----GLGTRTDILDHVNADTYLRTGEALTGSDLDRIRSSEAALLGAVGDPR-LGDTSYVRGVLTTLRLELDLYVNYRPARLWHDRLSPLRDPARRAIDCVIVRENTEGLYSGIGGGARTGTPEEIAVDVDLSTRHGVSRVLEFAFSAARR----SVCLVDKANAVRNGGQLWQRCWGEAVARHPHIATSHLYVDTAALRLATDPTGFDVIVTNNSYGDILSDLTAALAGGLGVAASANLNP-VTGRALFEPVHGSAPDIAGSGTANPFGAILSVALLAEHLGRNEEADAVRRAV-----AAAVAAGRVTPDLGGPLGTKEVGAAVLAELRR
97 UniRef50_D1B742 3-isopropylmalate dehydroge... 332 1e-89 1 35.9% 2:360 1:367 -MKSYRIGLIPGDGIGPEVTAQAVKVMEAAGSLFGFSLELTHYPY-GAEHYLSTRQVLPDHALEEMEGLDALLLGAIGDPRVQPGIL-ERGILLKLRFHFDQYANIRPVRSF--TPGPL-----GSVNAVVIRENTEDLYVGIGseVTRGgpKRFAMQVAWHTLDGAARACQYAFDLALDLGAEEVTLATKSNAVRDLYGIFENACHQVASQYESVSLRVENVDALCYKLVRSPGDFRVILCPNMFGDIVSDLLAGIGGGMGLAPSGNVGDR---LSMFEPVHGSAPDIAGQDRANPVASILSGAMLLRHLGETS-----AAKAMEDAVQRYLSGPvlPIEMGGRLGTRGAGDAVVRRLE-
98 UniRef50_C7P3E9 Isocitrate dehydrogenase, N... 331 2e-89 1 29.4% 2:361 30:423 -PENPIVPIIHGDGIGKDVGPAAQKVLEAAANATGREISWMRV-FAGESAREKYDENLPDDTVNAIDEHRVAIKGPLTTP----VGAGFRSLNVALRQTLDFYSNVRPTYYLDGVPSPMKA--PEEMDMVTFRENTEDVYAGIEWEAGTEEVEQvgIGIKPITEFGSKRLVRKAIDYAIEHDRDKVTLVGKGNIMKFTEGQFTEWGMEVaeEYPdvMVESRLADAMLQWMQLRTDEFSVLAMPNLNGDYLSDAAGAQIGGLGIAPGANFGDAR---VLAEPVHGSAPKRAGQNMANPTAMILSGRLMFDYMG-----WKDAADLVRDAVEETISSGTVTYDLErkLGTEEYSDAIVENIEK
99 UniRef50_A1WHK9 3-isopropylmalate dehydroge... 331 3e-89 1 31.5% 5:359 1:350 ----MKIVVLPGDGIGPEIMAVAVRVLEAASKRFQLDLEI-GHDIAGHASLQRHGATVTPALLEKVKAADGLMLGPMATYDFKDEAKGEINPSKFFRKELDLYANIRPARTFPGMAH-----RVGEFNLAVVRENTEGFYADRNIESGSSetPDTVISLRRITRLCCERIARSAFDLARTRAR-HVSIVHKANVLKIGDGMFVDICRQVAREFPQVRVDDFIVDAMMAHVVRAPQRFDVIVTTNMFGDILSDLTAELSGSLGLGGSLNAGKDH---AMGQAVHGSAPDIAGRNIANPYSLILSAGQLLGWHGQRkpAFALAARAIDETATAALQAREGTRDAGGELGTAEAGQSFVRRL--
100 UniRef50_B8NJA6 3-isopropymalate dehydrogen... 331 3e-89 1 31.2% 5:360 1:345 ----MRIGVLKGNGIGPEITAATIRVIEA----TGIQPEWDFIPIA-DEAVRLYGHALPPQVIQRIKDVKFCIkgRISCTQTDGSVVTYPSINNAIRRELNLFVNPRPIRGYVGISG-----RHEKMDMVIMREITEDTYIGWEKPLEDGA---AAEAIKRVTRSASWKVSQYAFEYARKHGRKKVSCLHKANVLHETDGLFLRTFQEVARLYPDIVGDDMMIDAACYSVVRDPCWFDVVVTVNQYGDIFSDLAAGLAGSLGLAPGANIGDSA---STFEAAHGAAPDIAGTGAANPIALILSGAELLAHAGYG-----KGSEAIREAVTRVIEAgtLTPDLGGRSTTEQVADAISVEVR-
101 UniRef50_A0D2B8 Chromosome undetermined sca... 330 4e-89 1 27.2% 6:361 34:355 -----NVTLIPGVGIGPEITNSVKTVFEAL----HVPIKFDVLDNFNFEN---------DDSKSQLRKNECILLGVMTEKNQKYTD------NYKFYKYLDLYSNITFAFSVEGIT-----QRHNNTDIVVIRENTEGEYSGVEHEVYPG----VVESIKVTTKQASLRIAEYAFEFAHLSGRRKVTAVHKANIMKLVDGLFLQACREVAQRYSFIKYEEMIIDNCCMQLVKNPTQFDVMVMPNLYGSIVQNVVAGITGGVGMAAGASIGKDHALFS--QGCRHTGRDIAGKNVVNPSAMLVSSTLLLRHLG-----LPNFADQICRAVQHTIQdkIKTKDIGGNATTDQFTSEVIRSLGR
102 UniRef50_Q8XSY8 Probable 3-isopropylmalate ... 330 5e-89 1 30.3% 5:360 1:355 ----MRILVLPCDGIGPEIVGAAMEVLRSADSVFKLDLAFDYDDV-GFTSLEKYGTTLRDEVLAKAKTYDGVILGTQSHADYPAPDKGGRNVSAGFRIGLDLYANVRPARTRPFLTSNMREGRT--MDLVIMREATEGFYPDrkGWAELMPSPDMAISLRKITRHCSERIARRAFELAMKR-KKKVTAIHKANSFHMTDGLFLECVRDVARDFPEVRLDDLLIDASTAHLVRAPERFDVLVATNFYGDIISDLASELSGSLGLAGSMMASDTH---CCAQAQHGSAPDIAGQDKANPVSMILSVAMLIQWMGEHhpAYLAAAQAMEAAVDSVLEnaTRTPDLGGNCGCKAFGQLVAKVIQ-
103 UniRef50_A9UQS3 Predicted protein n=1 Tax=M... 329 7e-89 1 29.7% 3:359 32:378 --QAHTVLTFDGDGIGREIVSAAKECIEA----TGVNIRWEQMDM-GYEAMQNTGVYIDDSHMDAFEEIGVLFKGPLTVPPKdvRGKRYTSGNQVFRKYFQLFANVRPVRSMPGVRAP-----FNDVDLVVIRENTEDVYTGEETWVDADTVHCV----KRISRGASERVADFSFKYARDNQRKRVTALHKANVCKQSDGLFLNTFHERAadLGGIIADDQLADSCLTKLMIEPKSFDVLCCPNLYGDLVNPLSlgMVGSLGLCPSGNIG---THQALFEPAHGSAPDIAGKGIANPTSQILSGCMMLSHLGEF-----EASQRLENALRAMYASGIVPVDFGGQADTKEVVAAVLKHL--
104 UniRef50_D2SEJ6 3-isopropylmalate dehydroge... 329 1e-88 1 42.8% 5:357 1:336 ----MRLAVIPGDGIGPEVVAEGLKVLRAVAP----DVESTPYDL-GASRWQRTGELLPDTVLDELRRHDAILLGAIGDPS-VPPGILERGLLLRLRFELDHHVNLRPARLFDGVRSPLAAPGA--IDMLCVREGTEGPYVGNGGVLRRDTPHEVATEVSLNTAFGVERVVRYAFERALARPRRHLTLIHKTNVLTHAGSLWSRTVEEVSAEFPEVTVAYQHVDAASMFFVTDPGRFDVIVTDNLFGDIVTDLAAAVTGGIGLAASGNLDASGTNPSMFEPVHGSAPDIAGKGVADPTATVLSVGLLLDHLGRADQ-----ARKVNAAVAFDLS----TRDPEAQVRTEDVGDRLAA----
105 UniRef50_Q6GG12 Isocitrate dehydrogenase [N... 328 2e-88 1 29.2% 2:360 16:422 -PNEPIIPFIIGDGIGPDIWKAASRVIDAAVEKagEKRIEWKEVLAGQKAFDTTGEWLPQETLDTIKEYLIAVKGPLTTPI----GGGIRSLNVALRQELDLFTCLRPVRWFKGVPSPVK--RPQDVDMVIFRENTEDIYAGIEFKEGTTEVKKvgIGIKPVSKEGTERLVRAAIQYAIDNNRKSVTLVHKGNIMKFTEGSFKQwaQEKAEKEGKIIIKDSIADIFLQQILTRPAEHDVVATMNLNGDYISDALAAQVGGIGIAPGANINYE-TGHAIFEATHGTAPKYAGLNKVNPSSVILSSVLMLEHLG-----WQEAADKITDSIEDTIASKVVTYDFAreVSTSAFADELIKNLK-
106 UniRef50_UPI00019260EC PREDICTED: similar to predi... 326 6e-88 1 25.5% 4:360 45:376 ---RHTVSLIPADGIGQSLIMGIVEVFQ----NSGVPVDFEECYITGDTNEEKMKS--FNDIKTSVLRNGTALKGNWATSMGIDS----KSYNVLLRHDLDLYANVVKFKSYPTVIT-----RHNNVDLIVIRENTEGEYTNLEHENIPG----VIEMIKIITKKKSERIAKYAFDYAMENNRKKVTAVHKANIMKLSDGLFLKVCKEVAEGYPEIDFNDMIIDNCAMQMVSKPEQFDVIVTPNLYGNVLSNIAAALVGGPGLPHGENHG---NGIHVFegTRNSGMDIATKNIANPMSMLFAATALLRHL-----QLSKHAQLIESCIHKIVTTNqrTVDIGGNTSTSEFFEILVKEVE-
107 UniRef50_Q48806 Protein dlpA n=5 Tax=Legion... 325 1e-87 1 28.7% 3:361 5:368 --DPIKIAVLPGDGIGIEVTEATLPVFEVL----DVPVILNYGDI-GWEFWKKEGAAIPSRTWQLIASSDTVLLGAITSKPQrkSNPYYVSPVIQLRQGLDLFANVRPCFSIDDQSKP--------FNFCIIRENSEGLYCGFDYFPLPKaaDEASCALRLQSKSGLTRLFDFAFKHAMQTGMPRVTLADKPNVLRESGEFTRKIFESTAQRYPKIQADILNVDAVALWLIKSPEKFGVIVAENMFGDILSDVGAGVMGGLGLAPSANIGDKGSY---FEPVHGSGPRIR-KNCANPSAMFLTISMLLNHFGYPDR-----AKKIVNAVMQVIKEkfITYDLGGHATTTDMANAVIEHCAR
108 UniRef50_Q1IMD5 3-isopropylmalate dehydroge... 325 2e-87 1 31.5% 2:360 1:395 -MARPTVVTMPGDGIGNQVLPQAIRVLEAV----GFEANYVHADI-GWECWCNEGNALPDRTIQLLRKHKLGLFGAITspELRGKGLSYFSPIVTMRQLFNLDVCMRPCLSFPGNptTCGGFEEPQVDVVVFRQNTEGLYAGVEWTNPPEngEELAVSVRIITKKNAQRICEAAFKHAKKYRYKNVTICEKPNVLRETSGMMEEVAKQVQKQYPEIALWSTNIDAQTMWLTKNPEEYGVIVASNLFGDVISDAFAGLVGGLGFAASGNIGDE---VAVFEPTHGSAPKYAELniVNPIAMILSAAMMLDHIGESEK-----ADRIRKAIADVVKEGkrTYDmgGpaNTVQITDAILVHVE-
109 UniRef50_A4WLX6 Isocitrate dehydrogenase (N... 324 2e-87 1 27.2% 2:361 42:438 -PDKVVIGYIEGDGIGPEVAYAAIKVANEAVEKAYGkqITWYEIVVGEKAEKLFGNRLPDQSIEVLRKIRVFLKAPLETP----VGGGFRSINVTLRQLFDLYANIRPVKYFPGLPSPLR--RPELVDLVIFRENTEDVYAGIEweFGVNIRDDAGIGIKPISKFGTQRIARLALKFAIENKRRVVTVMHKGNIQKYTEGAFKEWAFEVaaQYGgvLVNDRIADNMLQQLLTRTGEYDVILAPNLNGDYVSDEAAGLVGGLGVAPGLDVGD---WGMMAEPVHGTAPKYRGKNYVNPTATILALELMFRFLG-----WREVAEYIMKGVETAYREGYFTGDLARQMttQEFADKVVEIIKR
110 UniRef50_C0WN79 Isocitrate dehydrogenase [N... 324 4e-87 1 27.9% 2:360 16:420 -PNNPTIPFIEGDGIGPEIWKAAKTVFDAAVKKagQKQVNWLPLLAGETAYKKTGQWLPDKTLATLREYLVGIKGPLTTPI----GIGHRSINVTLRQKLDLYACFRPVTYYPGTPSPVVH--PENVNIDVFRENTEDIYAGIESDVDTKDAEesAFAIKPISKQGSTRLVDAAIDYAFANNRHTLTLVHKGNIMKKTEGGFKKWGYEAAEKYGdlIVNDVITDNFFQQALLHPEHFEVVATMNLNGDYISDALAAQVGGIGIAPGGNIN-YQTGHAIFEATHGTAPQFAGQNKLNPTSIILSGAMMFDYLG-----WDDVSNLIRIGIKRAIKSHHVTVDFAKtlSTSGFGEYVAQLIE-
111 UniRef50_Q4ZRW7 3-isopropylmalate dehydroge... 323 5e-87 1 32.5% 2:358 5:369 -MLRKRICVLPGDGIGIEVMEAALPVIAAL----NLPFDLVPADI-GWQCWRAEGETVPARTWEIMASCDATLLGAITSKPLagQNRRYVSPVIQLRQNLDLYANVRPVTDMTG---------ENRFRFVVIRENTEGLYAGLDFgwQREGQDDATVTLRLQTRSGLMRIFEYAFEYARKNHFTRVTFVDKPMVLRHSSAFARGIFEATAQRYPDVSGVIENVDAVALWMVQRPERFGVIVAENMFGDILSDLGAGVMGGLGFAPSGNFGNSG---AYFEPVHGSAPAHAGLNKANPGAMFMAIALMLEHLG-----FPTESACISQAVSLVSRTSTRTYDLGGSHTTAQVGEAIVQQ---
112 UniRef50_B7UV18 Isocitrate dehydrogenase [N... 322 1e-86 1 26.0% 2:359 26:418 -PKNPIIPFIEGDGIGVDISPVMIKVVDAAVEKAyrKIAWMEVYAGEKATQvdQDTWLPQETLDAVRDYVVSIKGPLTTP----VGGGIRSLNVALRQQLDLYVCQRPVRWFEGVPSPVK--KPGDVDMVIFRENSEDIYAGVEWKAGSPEAEKvgIGIKPVSQEGTKRLVRKALQYAVDNDRSSVTLVHKGNIMKFTEGAFKDWGYEVARDekNVVVKDVIADAMLQQILLRPAEYDVIATLNLNGDYLSDALAAEVGGIGIAPGANLSDS---VAMFEATHGTAPKYAGQDKVNPGSLILSAEMMLRHMG-----WTEAADLIIKGTNGAIAAKTVTYdmDGalSCSEFGDAMIAKM--
113 UniRef50_O67480 Isocitrate dehydrogenase [N... 322 1e-86 1 27.3% 2:360 36:426 -PDNPIIPFIEGDGIGPEITQAMLLIINTAVEKtgSKKIYWVELLAGDKAEEKTGERLPQETLDVLKESIVGIKGPLGTP----VGKGVRSINSALRRAFDYYSAVRPVYWM-GQATPIPN--PERVDLVVFRENTDDVYAGVEFFAgeGFPEDVGITVKPMSEFKTKRHVRKALRYALENNKKNVAVIGKGNIMKATEGAFINWAFEVAEeeGQVKLTKVITDQMLMQLVLKPEAWDVIIAQNLNGDYVSDLAASLIGGPGFVPSGNIGDGY---ALFESTHGTAWDIAGKGIANPLSLTLSGAMMLEYIG-----WKEAAQKVYDAVRRTLAEHIGTPDiaKAVGTMEFAEEISKRIE-
114 UniRef50_P96318 Isocitrate dehydrogenase [N... 321 2e-86 1 25.1% 2:360 30:419 -PDNLIVAYFKGDGIGPEIVESAKKVLDAAVDKagTRRIVWWEVTAGEEAQKECGSLLPDGTLQAFKLARVNLKGPLTTP----VGGGFRSLNVTLRMVLDLYSNVRPVKWY-GQPTP--HCHPENIDWVIFRENTEDVYAGIEweFGIELTPDTGIGIKPISKWRTQRHVRRAMEWAIRNGYKHVTIMHKGNIMKYTEGAFRQWaeEVNTKYGgiIVNDRIADNMLQQIITRPGEYNVIVTPNLNGDYISDEANALVGGIGMAAGLDMGD---GIAVAEPVHGSAPKYAGKNVINPTAEILSGMYLldFVGWPEVKL-----LVEYAVKQAIAHKQVTYDLArpISTTEYTDVLVDYIR-
115 UniRef50_O43837 Isocitrate dehydrogenase [N... 321 2e-86 1 24.4% 4:360 48:381 ---SFPVTMLPGDGVGPELMHAVKEVFKAAA----VPVEFQEHHLSEVQNMASEEKL--EQVLSSMKENKVAIIGKIHTPMEYKGELA--SYDMRLRRKLDLFANVVHVKSLPGYMT-----RHNNLDLVIIREQTEGEYSSLEHESARG----VIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEY---AVFegARHPFAQAVGRNIANPTAMLLSASNMLRHL-----NLEYHSSMIADakKVIKVGKVRTRDMGGYSTTTDFIKSVIGHLQ-
116 UniRef50_Q5JFV8 Homoisocitrate dehydrogenas... 321 3e-86 1 34.6% 5:360 2:320 ----YRVAVIPGDGIGPEVIDGAVRVLKAVTGRVRF-----EYYEGGVDVFQECGSPIREEDLEEIRRSDAVLFGATTTPFDLP---GYRSLILTLRKELGLYANLR---IIPDLRT--------GREIVIVRENSEGLYFGIGAVV-----NGRAVDVRLITREGAERIARFAVEQAKARG-SFITFVHKANVL-TGDKFFRRIVREVAGE-EGVEVRDAIIDSFTIKLVRNPWEHGVILSENLFGDILSDLATVHAGSIGIVPSGNYGD---GIALFEPVHGSAPDIAGKGIANPIGAILSGAMLLDYLGLDGS-------LIRAAVRGYVVNGELTPDMGGRARTEDVVRGIIGEIE-
117 UniRef50_C7MQT6 Isocitrate/isopropylmalate ... 320 6e-86 1 36.2% 2:360 1:355 -MTGTRIGLIRGDGIGPEIVEATVRVLDALAELHPESRGWEYVEiaGADTYRRTGVACAEADVRRLreVDATLKGPVGLPDVRTPDGVEAGVLgiLRTGLDTYANIRPVRSWPGVPSRVRADR---VDYVIVRENTEGLYASRGKGVGNRW---AVTDTLLTTREGTLRVARKAFTLAAGrgVRRVTCVDKSNVLR-SHAFFREVVTEVAAEFPEVELEYRYADAAAQDLVLCPERFDVLVMENFLGDVLSDLGGATVGGVGLCPAGNVGD---GAAYFEPVHGSAPDLVGRNRANPVGQLLAAAMLLDHLGHVDE-----AARLRRAVSAVLAFGTVRIEADGTvgAEAVADAVIAALQ-
118 UniRef50_A0P1S6 3-isopropylmalate dehydroge... 319 7e-86 1 30.0% 5:361 1:361 ----MKIALIKGDGIGVDVAEAAIAVLETALKHTGEPAPRYDEIQAGAGYFKETGLDIEDGGEERAGLADAIFLGAIGLPSIRHANGTEISPHLRLRDRFGLYAGVRPVKAYPNAPQRLADPRAAGIDLVILRESTEGlySAAAHKRSLVVNDDEVQDVLRITRKTTTKLHRFAFNLARKrhPGRLTCVDKANVF-TSLAFFRQIFDEVKSEFADVPVGYNYVDAQALDLVRKPWEFDVLVMENMFGDILSDLAGGLVGGMGMAACGEIGD---TTGLFQPAHGSAPDIMGEDKANPLAAILSAALMLDYLAEkkPSLADAAELIDSAVETGFWHnlRPIEFGGDMGTRAVTKELLGRVAQ
119 UniRef50_Q0ZQ44 FrbE n=1 Tax=Streptomyces r... 319 1e-85 1 29.5% 2:360 1:362 -MRKHTVTLIAGDGSGPELVAAARTVLDTAAGSAGFHLDWDVRP-AGQGALRSVGELLPASTLDSIRRNGVALKGPTTTPI----GVGHRSVNITIRRELDLYACVRPVRVWPG-----AGAVDSGIDVVVVRENTEDVYSGLEYPADSDgdPGIAFSLKPITPGGSRRIVAFALDHARKNGRRKVEVGADVYRYPRTEGLFFEAARELGPEYPDIVTATVPVTVLCDSLVRDPADRDVLVLPNLYGDVISDVTAALVGGLGMAPGANIGDR---TAVFEATHGSAPEFAGSNRLNPTALILSGCMLLDHLGE-----APTAARIRAAVRSVLEEGrvTFDlaRAVTTTAYAEAVIERLR-
120 UniRef50_D2Y061 Isocitrate dehydrogenase n=... 318 2e-85 1 27.7% 4:361 56:387 ---RHAVTMLPGGGIGPECMGYVRDIFKYI----GAPIDFEVVDIDPTMDNDDD----VQYAITTIKRNGVGLKGNIETKSEA---AYVTSRNVALRNELDMYAYILNCKSYPGVAT-----RHKDIDVVIIRQNTEGEYAMLEHESVNG----VVESMKVVTADNSERVARFAFEFAKKNGRKKVTTVHKANIMKLSDGLFLETSRRLAKEYPDIEHDDMIIDNCCMQLVAKPHQFDVMLMTNLYGSIVSNVVCGLLGGAGLLSGRNYGDHY---AVFEptRNTGTAIAGKNIANPIAMINASIDMLEHLGH-----QFHASLLRRAINKTIndRVLTPDLGGSNTSTDVVGAILQNVGR
121 UniRef50_B8M3W0 3-isopropylmalate dehydroge... 318 3e-85 1 28.1% 1:356 1:365 MAEIRKLLVLPGDHIGPEIIAEALKILAVLEEELPNFKVQISYGLIGGASLDKTGSAITDEVLETAVASDAVLLGSVGGPEWapGALSPEKGILHLRQRLDAFANIRPCRFYAsnQSPLKPEIAAGVDFVLVRENCGGAYFGTKTEFEDEA------------RTEVERCARVSAALARTFGRGkvWNADKANVLASGR-FWRTVTHDieREFPDIELHDQLADSMAMVMVKAPTKFnvIHTDNTFGDILSDISGGIVGSLGVLPSASvgSEKPVKGIYEAVHGSAPDISGTGQANPIAQILSLAMLLRY----SFSMPRQADLLEDAVRKTLelGIRTKDLGGSASTQDVGDAVA-----
122 UniRef50_P41560 Isocitrate dehydrogenase [N... 314 3e-84 1 25.4% 2:359 24:415 -PNNPIIPYIEGDGIGVDVTPPMLKVVNAAVAKAYgkIEWLEVYAGEKATKmdSETWLPEETLNILQEYKVSIKGPLTTP----VGGGMSSLNVAIRQMLDLYVCQRPVQWFTGVPSPVK--RPSEVDMVIFRENTEDIYAGIEYKAGSDKAKSvgIGIKPVSKEGSQRLVRQAIQYAIDNNKDSVTLVHKGNIMKFTEGAFKDWGYELAIEekEIIIKDVIADAMLQQVLLRPAEYSVIATLNLNGDYLSDALAAQVGGIGIAPGANLGDE---VAVFEATHGTAPKYAGKNKVNPGSVILSAEMMLRHMGWLE------ADLLLKGMSGAIQAKTVTYDfaTLVSCSAFGDCIIDHM--
123 UniRef50_D1B6F8 3-isopropylmalate dehydroge... 313 8e-84 1 28.3% 3:359 13:390 --DRYKVCYMPGDDSGFDMMEGALVVLLSM----DLPIDWVRADLGWCMWEkgQGDpvPPETIDKIRSSDATLMAAITSKS---GVKGFKSAILQMRQLFDLYINLRPAKTLPDLGSPLKGD--PKIDLVLFRENTEDLYSAVEFHPLPEEmgDVAVSWRVFSSVGCERIIRAAFEYAKSTGRTKVHCCNKANVIRETDGMMKRIFLEVAKEYegITGIEENADATAMWLIKNPQDYQVIVTSNVFGDILSDEASQLTGGLGFAPSGNIGEN---TAIFEPCSGSVPKYAHQYRVNPSAMLLTSKMMLEYLG-----LDQAGQKIEWAINEVLKekTLTYDirNAASTIEMATAIAQKI--
124 UniRef50_Q9ZN36 Isocitrate dehydrogenase [N... 311 2e-83 1 24.9% 2:359 27:425 -PNYPIIPFIEGDGIGSDITPAMIKVVDSAVQKagEKKIAWYEVFVGEKCYQKFKdwLLPDTIEAINHYKVSIKGPLTTPI----GEGFRSLNVALRQKMDLYVCLRPVRWY-GSPSPVKEPQ--KVDMVIFRENSEDIYAGIEWQEGSAepESSGVGIKPISKEGTERLVRKAIEYAIDNDKPSVTFVHKGNIMKYTEGAFMKWGYALakEfkEIIIKDMIADAFLQQILLRPSEYSVIATMNLNGDYISDALAAMVGGIGIAPGANLND---TVGMFEATHGTAPKYAGLDKVNPGSIILSAEMMLRHMG-----WVEAADLIVSAMEKAIKSKKVTYDFAreVKCSEFASVMIENM--
125 UniRef50_A9A2N6 Isocitrate dehydrogenase (N... 311 2e-83 1 30.5% 1:361 1:343 MSK--KAAVMKGDGIGPEVVDSMLRVLKECNFQSELILCE-----AGSEQWDKNgsYIPDVTMKILEETDCCFKGPTTT---IPVPGAPRSVAVTLRQKFDLYANIRPTKTYD------RLTPDRKLDCVCFREATEGLYTGVEAKI----TDDAAIAIRKITRQGSRRLIDSAVDWANKFNMKKMVAVTKRNILKQTDgfWDETQKAV--EGTDIELSEIYIDNMAQQMVIATEQFnvLVSTNLFMDIISELASALVGSIGLIYSANIGDNY---AMFEAAHGSAPQFAGQNKVNPTATVLSGAWMADYLGERDVR-----DAIFAATEQVINEGkvTWDIGGDASTTQMTDAIieKLRK
126 UniRef50_A1WV93 3-isopropylmalate dehydroge... 309 7e-83 1 39.1% 3:360 6:382 --ESWQVAVMPGDGIGPEVMAATRHALEAL---PGPALVLTELGWPAHAWHRDHGEMMPADWRGQLAGYDALLLGALGDPGPSHDAQRylAPLLQLRKGLDLWACERPAVPLAGAPMPLSDPRALHTDLLVIRENSEGEYVDQGGRLAAGTPRETATQLEVFTRAGTERIIRHAFERalRAPraAVCVVTKRNAVQYAGELWSEVFAEVAAEYPGIATHHELIDACCMKFVSQPWQFDVVVASNLHGDILTDLAAVLAGGMGVAPSANLNpdRSVPPLFEPTHGSAPDIAGADRAHPAAMLLTAAAMLEWMGEVDPVAARSAVQLQRAVAEDIAEHG----MGGR-GCAEVGRAVAQRIR-
127 UniRef50_Q3IKZ8 Isocitrate dehydrogenase, s... 309 1e-82 1 26.1% 2:358 29:418 -PLQPIIAYIDGDGVGQDVMPVMRKVVDSAIAHCYqkIHWMQVYNGEQAAKLYDGDWFPQETINAVRECKIAIKGPLTTPL----GGGFRSLNVALRQEMDLFVNMRTIKGFSALPSPLKNPYL--TNITVLRDSSEDVYSGIEWQAGSVESEKvgIGIKNISKEGSERLVRYAINYALKNNSESLTLVHKGNVLKFTDGAFKRWGFALAkeypPLIIKEVIADNMLQQCLMHPEQFDVVATTNQNGDFLADMLSAQVGGVGIMPAANLNNE---VAFFEPTHGTFARIAGQNKANPSSSILSAVLMLKFM-----QWHEAANLIENALERTLAAGEVTFDLLspLSCTDFALRVIEH---
128 UniRef50_A1SWV5 3-isopropylmalate dehydroge... 306 6e-82 1 30.8% 2:361 1:364 -MTTYNIALLAGDGIGPEVMKEAVKVLKLIEQreDVNFELNDVLFGAAAYF-AMGHAFPDETKAACDKADAILKGTIGLNHEdiDEQPERGALLPLRRRYNTFANFRPVYLPKGLasPLKASvgEGIDIMIIRELVGGLYFGEKEMGVNADGKRFVREVLEYDEDQIRQIVKVGFEVSMKR-KKVMHNIHKSNVLKSS-VLWNEIVEEESKNYPEVEVKNILVDAAATYLCLNPGMFDVMVMENMFGDILSDQGGGILGSLGLMPSACKGPDKSY---YEPSHGSAPDIAGKGIANPYSMIGSVALMLE----MSFGLEKEAKNLWAAMQAVFENGYSTSDlaNLVSTAEFGDLVCAELAK
129 UniRef50_Q4P2R4 3-isopropylmalate dehydroge... 306 7e-82 1 24.0% 2:360 10:359 -PKAFKVMVLQGDHIGPEVMAEVLPLFDVIQSHFGIKVETFERLIGG-SCLDQHDCPIQESTLQEASECHAVLLGSVGGPKWDVGDsrPETGILRMRKHLNLYANVRPAKIISERqsSLKEHVVRGVNIITLRENAGGIYFGRKQEPDPLAH-------------------KAALSLASSHGPLPIISVDKANVMATSRLWRQVVTETIRDEFPQlkLSHQLVDSAAMLLAKDPRKLnvVLTENLFGDILSDLTSVIPGSLGVLGSAEIddFRMPMGVYQPVSGSAPDIAGKGIANPIGMFMSFGLMCRW----SLGLPKAADAIDSAIKDCLESGQCTRDVGGTLSTQQAGSALRQSIQ-
130 UniRef50_Q18GT1 3-isopropylmalate dehydroge... 303 5e-81 1 32.6% 1:359 1:331 MSreHEIVVIEGDGIGQEVIPAAVAVLQAVDE---VGFSFTEK-QAGDDTRDQTGAALPETTYEAAADADATLFGAAG--------ETAADVILPLREAVGSFVNIRPARAYPGV-----DALQPETDLVFLRENTEGVYSGHEDRLS----EDLSTLTRVITTSASEQLAEYACSYVTERSIDGFHTVHKANVMQETDGRFRDAVSRVAAS-NDVATNEVLMDAFATRVCLNPTQFDVVVCPNLAGDVLSDLAAGLVGGLGLLPSANIG---QTNALFEPVHGTAPDIAGDGIANPSASILSAGMLLEYLGETD-----AATNVQMAVESVLNSGPRTPDLGGNASTEAVVNAVIEQL--
131 UniRef50_B2J8P1 3-isopropylmalate dehydroge... 301 2e-80 1 33.3% 3:359 7:347 --ASYRIVAIPGEGIGPEVVEASLKILQHVAKIQGFTLQVD-YGWLGATAFEQLGSYFPQATTELCDGADGIVFGAVS-----------QGGLLELRKHFDFFCNLRPIRSVNSlkSSLRPEKIQGLDILIVRELVSGIYFGPSGRSSDERGN-YGYHTMRYYDEEIRRIARKALEQAQYR-RGLLTVAHKENALPH--LHWTRLVQEEATKFPNVIVEPMLVDNLAMQMVLNPQRFDVILASNLFGDILSDIGGALVGSIGLLGSASLNA--NGFGLYEAIHGTAPDIAGLGIANPLGTLGACVLMLQQWGEVQAAQQIIAAQ-----DRILAKGYRTADLFTqvNTATLVDLLLEEL--
132 UniRef50_Q05FQ8 3-isopropylmalate dehydroge... 300 4e-80 1 27.1% 5:355 2:341 ----INLLILPGDGIGPEIIKQVIKIVKS-CIYTGYKINIIYNYIGGIS-IDKFNTPITNNLISIIKYIDTIFLGCVGGYKWNHSIFKPEYGLLKLRKKFNFFTNIRPIK-----------CPFKNIDIIIVRELNGGIYYGKPKGFSKQIINQiaYNTKIYNEQEIIRLARISFNLALNR-KKKLCSIDKSNVLE-TFKLWKKTINYVHKFYNKVKLSHIYIDYATIDLIKNFNKFDVIITSNLFGDIISDLCSLLTGSLGMLPSISINN--KSLSLFEPCHGSAPDIANKNIANPVGALLSLVMMFEYV----LNDFKLSNNLYYSIYKVLSYGFCTIDMKKyvSTEEFGDLV------
133 UniRef50_D2VM48 Isocitrate dehydrogenase n=... 297 3e-79 1 25.8% 6:361 39:423 -----KVTLLPGDGIGVEICSCVCELFHYA----NIPIQWDTYLVSGseDPRRRGETNppDLHQSILNNKVVLKGPFITRDVSKSIDRMLAL------KYGLYAHVVPVKAPQNLP-PSVFTPFRDVDMVVVRENTEAEYSGLEHQVQPG----VVESLKIITRDGSMRIAKWAFEYAKQSKRSKVIAIHKANIMKKSDGLFIECCKQVAKEYPDIQYSELIVDNAVMQLVKNPHSFdvVVTPNLYGSIVSNTASSLVGGVGVISGFNATDINKPDavFegNRHVAMDISGRLIANPIGLISSSIQMLDHMG-----MNTHANRIKFALKETLLnkILTPDIGGTGSSVSFIEAMMRHIPK
134 UniRef50_A6G3V7 Probable 3-isopropylmalate ... 297 3e-79 1 32.7% 20:358 1:362 -------------------MREGLKVLHAVSEPLGIEWAIEDVPCGGQYYLEQGDLDWPSDAPQKCDAADLILLGAVGWPDPAGTGGPVlsPVIGNRMRLNLYANVRPIKLYPGVQHRIHgwEAGKVDMVIIRENTEGLYAPTGGKLAPGGKADVAIDTRVITRRACEQVIRHAFELCKRRNKgrVTAIIKDNVL-HGCQLFRDVFFEIGAEYPEIEKDTAIVDAFTQWLVGQPEYYDVCVTSNMFGDIVTDLASTLQGGMGMAVGGNIG---KHNAMFEPIHGSAPKHAGKDKVNPIAMILSVKEGLEWLAArdATLTKAAEAIEAAVVEVLEKgtLTYDLVGnsKCSEVGSAIAEA---
135 UniRef50_UPI0001C163C2 Isocitrate dehydrogenase NA... 294 4e-78 1 25.5% 2:358 24:471 -PDNPIVPFIRGDGTGIDIWPATEKVLDAAVAKAYnkISWFKVY-AGDEACDLYGTylPQDTLTAIKEYGIAIKGPLTTPI----GGGIRSLNVALRQIFDLYACVRPCRYYAGTPSPHKS--PDKLDVIVYRENTEDIYLGIEWKQGSEIGedAGIGIKPISRSGSQRLVRRALKHALQLPKEkvTLVHKGNIMKYTEGAFRDWGYELaeKNPQISLEerMIdsIFQQIQTRPDEYSILATMNLNGDYLSDAAAAIVGGLGMGPGANIGDS---CAIFEATHGTAPKHAGLDKINPGSVILSGVMMLEYMG-----WQEAADLIKRGLGASIADGKVTYDLArpLKCSEFADTIIQQ---
136 UniRef50_UPI000185C11E 3-isopropylmalate dehydroge... 292 9e-78 1 32.1% 3:360 13:393 --APRRITLLPGDGIGPEITDACRGLIADVFPHWEL-----TETQIGWSQWRAHGNPVPQETWETLGRSDAALLAAITspHLRGTGLNYRSPVLQLRQRLDLFANIRPV-TLPGAAA----------DFTIVRENTEGLYShpPHDAPADSPheVAVSLRVTTSFAWHRLARQAAKLALARQAAnvTVADKPNILRDSARVIRGAVEEVAEEYPQVAFDFANADAVAMQLVTDPARFDVIIAENLIGDILSDIGAGLIGGLGLAASANVGDN---FAVFEPVHGSAPDIAGRGIANPAAFLLSAAMCAEHLGAPVSELAPAA-KLREAVYAATRTAP-TLDLGGTATTSEFVAAVRAELG-
137 UniRef50_O15384 NAD (H)-specific isocitrate... 292 1e-77 1 27.9% 39:335 1:274 --------------------------------------DFEEVHVSSNADEEDIRNAI-----MAIRRNRVALKGNIETNHNLPP--SHKSRNNILRTSLDLYANVIHWKSLPGVVT-----RHKDIDILIVRENTEGEYSSLEHESVAG----VVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVY---AVFeaTRNTGKSIANKNIANPTATLLASCMMLDHL-----KLHSYATSIRKAVLASMDN--------------------------
138 UniRef50_UPI000186E03D isocitrate dehydrogenase, p... 291 2e-77 1 25.5% 4:360 37:369 ---KTNVTILTGSGIGPEIMDHTLRVLKAA----GAPLSYEIFALSSKDGSKNND---FDEALTSIRRNRVALKGNIELQSKNP---HIKSRNIIFRKTLDLFVYILFCKTFPGLS-----NKFGEIDITVIRQNTEGEYLMLEHEPRTGS----VESLKVLTRFNLERLIEFAFDYALTNDRKLITVVHNANIQKLTEGLFLNAANKISKSYPMIKMNVLDVNVAIFKIASNPRIFDVILATNLNGSMISNYLNGMLGGPGLTSGINFSAD--GIAVFEpaRNKGSSIVGLNRANPIAMIMSGINLLHHLGY-----NKTAEMIHNSVYATLvdKIRTPDIGGQATAEETVDHIIRHIR-
139 UniRef50_A9KQX3 Isocitrate dehydrogenase (N... 291 2e-77 1 26.5% 3:360 40:385 --DKIIIGVCGGDGIGPAITSQAQRILEYLLKDDIlkVEFKVIDGLTIERRAAEHAAIPAEVLKELKECHVILKGPTTTPRKGDPWPNVESANVAMRKELDLFANVRPVRIPE-----------QGIDWTFYRENTEGAYAV--GSKGIHVTEDLGVDFTVVTSGGSERIIRAAFEYAKANGKTRVTAVTKANIIKTTDGKFLDIFREIAKDYKDITADDWYIDIMTAKLikRRKDFQVMVLPNLYGDIITDEAAEFQGGVGTAGSANIGKRY---SMFEAIHGSAPRMVQEGraDPCSVIRAGAMLLAHIGYG-----KEADKLYQALdtVTEKKLVITGRNTGATGAEFADYIMETIE-
140 UniRef50_D2RML7 Isocitrate/isopropylmalate ... 291 3e-77 1 23.5% 5:361 47:391 ----ITVGILPGDGIGPCIMEQALRVAKYLleMASGKVEFRTIPGMTIEERVQKNESLPAEVLEACKACDVLVKGPFVTPRAGDPWPNMVSANSLLRRALQLYAAVRPVRIPE-----------KGIDWTFFRENIEGEY--IWGNKGIQVDDDLAVDFKVLTRPGAERICRAAFEFAKNNGKTNVTVVTKANIVKLVDGNFLKTAHALEKEYPGITVREELVDSMAAKITDqtKGMQVFLLPNLYGDIVTDVAAEYQGGLGTASSSNIGDQY---ALFEAIHGVGNFLVQHNraDPCSLIRAMGEMISHIGYPEKKEQLVKAL--DICTRTERKVVITTDKDG-ATAEEFTDYLLDTLQR
141 UniRef50_UPI00016C59BF Isocitrate dehydrogenase (N... 279 9e-74 1 25.7% 6:359 3:341 -----KVIFVQGGGLGQDQELSVRRLFAAAK----VPVEFE-VHLAGRMALEHGKDALPKATFDAIRECGLALkkGVGMPTAHGPSSVPTNYNVAFRRQLGLFASMRPVHNLPGIPS-----RFTGVDFLLFREITEDLYTASEHEIVPG----VVQSFKIVTEAACLRFFKLAFDTARKRGRKTVHCIHKANILKMADGLFLECFYRVAKEYPEIAAKDLIVDNTCNQLVSRPQQFEVLAAGNLYGDLLSDLGAGLVGGVSTTAAINKG---NGTTVYEAVYGASHEAVPPDMSNPLPLILPAIELLKDLGETGT-----AGRIQKAVETVLLEgiRTRDIGGTATTTAFTDAIVSRM--
142 UniRef50_C0W9Q2 Isocitrate dehydrogenase n=... 279 1e-73 1 24.9% 5:361 38:382 ----VKVGIMPGDGIGPYIMKAALLVARKLLKKEIADQRVEFVPIKgiEERARQNKSLPPAVLEACKACDILVKGPFVTPRAGDRWPNLLSANSLLRRQLQLYAAVRPIRIPE-----------KGIDWTFFRENIEGEY--IWGNKGICVGDDLAIDFKILSKPGAERLFRNAFEYAKSSGKTNITVATKANIVKLVDGNFLKVAHAMEKEYPGIHVREELIDSLSAKLM-DPegMQVFVLPNLYGDILTDIAAEYQGGLGTASSSNIGDQY---AMFEAIHGVGVYLVEHNraDPSSLIRAMGEMMAFIGYPEKRDRLFKAL--DFCTKVERKAVITTDKDG-ATAEEFAEYVVETLHK
143 UniRef50_C5EHC0 3-isopropylmalate dehydroge... 279 1e-73 1 25.1% 2:359 11:369 -SRIYTIALIPGDGVGPEITREAVLTLKRAGEVYGRSFQFTEA-IAGTAALDRGQCPLPRESLKTCLEADSILMgaVGRHPGLKFEERPESILGLLRTGLCLRSDIRPCFFAEALrcPLKEerKKGMDILIIRDIAGGMFT-TEGKSSNLCNVRAAWDTESYDETLIRDSARLAFQLAASRKR-KVTSLDKA-ILLSSSVLWRQILEETHRDYPEIELEHMLVDHGAFKLVSSPDAFDVIVASNVFGDIIADEAAGLTGAGEFLPAGSLNAERKGIYCPNQLHQVHEELAGTGRANPVGMILAAAMMLEY----SFGLVREAEGMKRAVSIVMEQGIHGRpsGgtADTAAIGEAVRECL--
144 UniRef50_UPI000038E0FC 3-isopropylmalate dehydroge... 277 5e-73 1 30.7% 7:355 4:345 ------IAVIPGDGIGKEIIPQVCDLVTSIDPSVNFTF-----YNISSERYINKGITIKDSEIDELKSYNSIFFGAIGDFRVKPG-IMEQGVILRLRKELDLYMNIRPAISFSRITG-------NNIHMTILRENKEDFYSDISgdINSESDDTIYYTMGFLSRKNLKRFFNMAYKIA---DTETVTITDKANAVDMYS-LWREIAIEESEP-AGKKINFEYADSLAYNMINNPLKYRYIIAPNLYGDILSDMSSAMVGGLGYAPSGNIGD---YSSMFEPVHGSAPDIAGKNIANPVASILSCIMMLKHLNQTET-----AGIMEKSVENVIRNGTIPIESGGNAGTHEFINKV------
145 UniRef50_Q0A635 Isocitrate/isopropylmalate ... 274 4e-72 1 26.9% 7:359 30:373 ------VGVLPGEGVGPEVIDVALSLLRLLGEATGQRFEVRTGGPIGRQAERLTGRGLTPEV----RDFCAQVFAQGGAVLCGPGGGRF---VYDLRRHFDLYCKLIPLRHWPALagVLRPEAARSADVLIVRENASGLYCGEWGSEGEGA-ARSAYQVCRYRADEVERILRTALRLAGQR-RGDLVVVTKPGGVPAISALWHDALTAVAGEHGAVRCRTLEVDNAAYQLIADPRQFDVIVCPNMFGDILGDCGSLLMGSRGMSWSGNYGA--AGQAVYQTAHGAAWDLAGRDRANPIGQVCSLAMMLR----ESFRLPALADALETAIARTLARGVRTADIQgaVGTRAMGQALCASL--
146 UniRef50_B5RJP2 FI08066p (Fragment) n=18 Ta... 273 5e-72 1 21.8% 3:359 85:408 --KTTKVTLINGEGVGRELMDAVQEVICAVKA----PIEWDVHD----EFKAKDSDDVSPEVLKSLRANKVGIKGPVDSRHWQR----------QIRKQFAQFAYVSLCSHIEGLDSPY-----GDFDVVIIRDQMEGDYSGIEHLVVPG----VMQTIKVSTTAGAARIAEFVFNYAVKNKRKRITVAHKANIMRMTDGNFLEAMRAEADKhdDVLFEERYLDTCILKILLKPHKCDVMVSSSMYGDVLRVIAGGMMGVPGICPGYSVSSLGT---VFDCRMKACHALAGKDLANPTGPLLSAALMLRHV-----KMDKQADQVDCAIRKVYKddIRTPDVGGKAKCSEFVKAVCDCL--
147 UniRef50_B8FQF2 Isocitrate/isopropylmalate ... 272 1e-71 1 30.9% 2:360 1:364 -MKKYTIAVIPLDGVGKDVIPLGAKAMQKAQelGGFELDCRYYE-AGVEYAVKTGKMCEDNLGEDIAKADAMLCGSAGHYDAdpGYKTGMQVLQFLRSGMGNSIGLRPLRLRKGIDCPLRN--REEIDVLLVRQLAEGFYIRPGHMIG----EDAAYDTIVVTRNVTEKFADTCFRLARGrgKKMVTLGNkgNV--TCFDFYRKIFTEVSAGYPDIGLQFTQVDALAEHLIKDPDRFDVIACENMIGDIIGDIGAYITGGMGITPTADVG---GVTPQFRPNHGTFPRAVGKGFANPLASILTAGLLLDTLgrGDDNLRRGARLIEKAVEYNLTtgPRTKDLGGTANTFATAEAVFKAME-
148 UniRef50_A9B3D4 Isocitrate/isopropylmalate ... 271 4e-71 1 29.5% 5:245 3:246 ----HRVTLIRGDGTGPELAEATRRVLEA----TGVAFDWDIQD-AGVDVMEQLGTPLPDSVLESIRSTKVALKAPITTP----VGTGFRSVNVAIRKELDLYACVRPCRSYPGVRS-----RFENIDLVVVRENTEDLYAGIEFERGTDEVAElgISIKPMSVPGSERIVRFAFEYARANKRKKVTAVHKANIMKFSDGLFLEVAREVAKEYPDIEFDDRIVDNMCMQLVQKPELYDVMVLPNL--------------------------------------------------------------------------------------------------------------------
149 UniRef50_C9SEZ4 Homoisocitrate dehydrogenas... 270 5e-71 1 30.9% 1:359 1:316 MsrTLRIGLIPGDGIGKEVIPAGRRILEALPSYLGLKFEFTDLH-AGFETFERTGAALPDKTVEILreCDGALFGAVSSPSS--PVKGYSSPIVALRKKLDLYANVRPVKTVLSAAKP--------IDMVIVRENTEDLYVKEETTRDTPDGK-VAEAIKRISERASHRIATMAGDIALRRQKIrvTITHKSNVL-----LRLK---------------------------------NVIVDPNLYGDILSDDAAALVGSLGLVPSANVGE---GFAIGEPCHGSAPDIMGQNIANPIATLRSAALMLEFLDEEAAAAKIYAA-----VDANLTEGklSPDLGGTAKTTEVIEDILRRL--
150 UniRef50_P80046 Isocitrate dehydrogenase [N... 269 8e-71 1 25.8% 2:358 24:472 -PNDPIIPYIRGDGTGVDIWPATELVINAAIAKAYGGREewFKVYAGDEACELYGTyfPEDTLTAIKEYGVAIKGPLTTP----VGGGIRSLNVALRQIFDLYTCVRPCRYYPGTPSPHK--TPEKLDIIVYRENTEDIYLGIEWAEGTEGAkdSGIGIKPISKTGSQRLVRRAILHAKRLPKAkvTLVHKGNIMKFTEGPFRDWGYELaeSNPdiEANAHMIdaVIKQEVEQvwKEKVMvtMNLNGDYLSDAAAAVVGGLGMGPGANIGDSA---AIFEATHGTAPKHAGLDRINPGSVILSGVMMLEFMG-----WQEAADLIKKGIGAAIANREVTYDLArpLKCSEFAQAIVSH---
151 UniRef50_A6GJ83 Isocitrate dehydrogenase n=... 265 2e-69 1 26.1% 2:358 6:338 -MNRYSIVELHGDGIARELSQAVHTVADAL----PFEIEFIPVDL-SDESREAKGDAIYDEAEAAMRRYGTSLKYPTATTK--------ESPNRVLRERCNFAVIHRPVATIPGIQTHYN----ERIHLDIVRIATGGTYEDAGRRINR----DTAVSIRAIERRPSVLASRFAFRLAQLRD-SNVIATSKYTIQKATDGLFQEAARGVARDYPATEFREELFDALLAGIIMRPERYGVIVCPNEYGDFLSDMAYGLIGSIGLGDSASYSFDSQgvAMFDPAGGTAPDIAGQNKANPTAALLAMANMLRHIGEHDS-----SKALRGALFGAIEAGEKTADIGGSLNLSEFTQVIVDR---
152 UniRef50_Q2HAA2 Putative uncharacterized pr... 261 4e-68 1 27.8% 2:361 1:331 -MATHNIVVFGGDHCGPEVVAEAVKVLRAIETHSPskFNLQEHLLGGAS-IKVHNDPLTAKALAAAKAADAILLGAIGGPEWGPSSprPEEGLLRLRKELGTYGNLRPCNFASDssSPLKADVCRGTDFIVVRELTGGIYFGA---RTEDDGSGFAMDTDAYSRAEIERIARLAGFLAltSPPSKVWSLDKANVLATSRLWRKVVTEVFANEFPQLEVGHQLIDSAAMLMVKSPRALnvVVTSNLFGDIISDEASVIPGSI-----------------------------GAGIVNPIGTILSVAMMLRY----SLNLPKEAAAVEAAVRTALDNGTRTKDLGGSAGTFQMADAVVVELVK
153 UniRef50_UPI00017936A6 PREDICTED: similar to isoci... 259 1e-67 1 21.5% 3:360 39:386 --RPIRVTVIEGQGTGPVVLAAVRKIFKAAL----VPVEWDYQTLSVYRDHKTNRMTVNPQLLDSAIETGLVLCAKDSSPRQND---SLESDSLALHKALNAFVGVRKFNSVVG------HEPYGPINLVNIREHVSGEYSEIEHLVSPG----VVQSIKTVSKKISVEVAKLAFDYACKHGHSRITVLHKADVMRLSDGIFLKACREVSACYPDVEYNEEKLDSFCLNVTTNPGRYEVLLTTSLYGAFAGSVCGMMSGGLVTVPTIAYGPKATVFSTMGdsHSDGDGIFKkqIINPTGIIRAAALMLDHAG-----MVVAGRCIAAAVEDTIRQGIRTQDMGGDASCSQFTDAIIKNLK-
154 UniRef50_Q6L0K7 3-isopropylmalate dehydroge... 258 2e-67 1 32.9% 7:337 4:317 ------VALIPGDGIGREIMPGV-----AAAISSISDINFVTFDISS-ERYIKTGIIIKDDELEELKNYRAILFGAIGDPRVRPG-IMEQGVILRLRRELELYMNIRPVRSFDD-----------KIKITILRENTQDFYTDISgeIDGSSCDEVYYTMGMLSYRYLKKFFNKAFSIC----DSTVTVTDKANAVKMYN-LWRSTAMEAAIE-KNINISFEYADALAYNMILNPKKYRYIIAPNLYGDIISDMGAALVGGLGYAPSANIGDK---NALFEPVHGSAPDIAGRDMANPAASIMAGSMLLEYLGYRDE-----SRIINDMVRNLYINGV------------------------
155 UniRef50_B7KHW3 Isocitrate/isopropylmalate ... 257 3e-67 1 25.4% 3:360 4:352 --TTPTIVVMHGDQTGEELLIQALRVLQPSVIR--QPLQFLDYDL-SLENRRATDNKVVWEAAQAARDSGLSLKAATITPEIAGDVG---SPNAILREALNAKVILRTGRRIPKI-RPIAGVYSP---IAIVRMAVDDAYGSKEWRETTENGDEIAYRTSKISRSTCRAVAEFTFQYA-KRTKAKVFGGPKFTVSATYEGMFKEELDAAAKRYPEVPYQPLLIDATFALLLQTTGESLVIPALNRDGDLLSDMVLQMYGSIAGSESLVlgSDQVKTVMAEAPHGTAPALFGKNIANPMAMILAGAALLSY--GRIPQAEKASRAIYESVFETIYEGKATPDLGGQMTTSEFTDEVIRRVE-
156 UniRef50_C5GTE7 Tartrate dehydrogenase n=2 ... 255 2e-66 1 37.3% 5:334 16:307 ----YKIAAIRGDGIGPEVIEAG---------NYQSAEETNRVAWILLNWPSRT------------------LSGAVRITRNTADISPISSSTFLW---FSSYLPLrpTRVFHGIQSPL------HLDWVIVRENSEGEYAGHGGRSYAGKPWEVATDISIFTRHGVERIMKFAFEAARSRAKKHITVATKSNAQRNGLVVWDEIAaeVAAQFPDVTCDKMLVDAMTARVVLTPESLDTIVPTNLHAGILSDLASALAGSIGIAPTSNLDPTRENPSMFEPVHGSAFDIAGKDLA----TFWTVAEMLSWLGQKG-----AAAELLECVESVCK---------------------------
157 UniRef50_UPI0001C31665 isocitrate/isopropylmalate ... 252 2e-65 1 27.3% 1:359 1:354 MPEPLKITILEGDETGQELLDQAVRVLD--PEVTGLPLELERFDL-SLENRRATQNGVVSDAAAAMRTCGFGIKAATITPEGADDVG---SPNRILREEVDGKVIVRTGRRIPGV-TPIAGVHYP---ISIVRMAIEDAYGAKQWREGdgAADEVAYRTEHVTRSTCRAVSEYAFRTARAMQ-ARVYGGPKWTVSPVYEGMLKEEMDAAAARHPDVAYEPVLIDATYAGLVsaADEPLVVPALNRDGDCLSDLVLPMFGSIAGAESVLldNYETHVAMAEAPHGTAPALRGKDVANPMAMLLASGAVLRHAAErhPGAERASRAIYESVLEAIATGIKTPDLGGHAGTTEFTDAVIERI--
158 UniRef50_Q961P4 GH13226p n=4 Tax=Drosophila... 248 3e-64 1 20.9% 20:359 1:307 -------------------MDAVQEVICAVKA----PIEWDVHD----EFKAKDSDDVSPEVLKSLRANKVGIKGPVDSRHWQR----------QIRKQFAQFAYVSLCSHIEGLDSPY-----GDFDVVIIRDQMEGDYSGIEHLVVPG----VMQTIKVSTTAGAARIAEFVFNYAVKNKRKRITVAHKANIMRMTDGNFLEAMRAEADKhdDVLFEERYLDTCILKILLKPHKCDVMVSSSMYGDVLRVIAGGMMGVPGICPGYSVSSLGT---VFDCRMKACHALAGKDLANPTGPLLSAALMLRHV-----KMDKQADQVDCAIRKVYKddIRTPDVGGKAKCSEFVKAVCDCL--
159 UniRef50_B4MP27 GK19462 n=1 Tax=Drosophila ... 246 8e-64 1 23.7% 19:343 1:294 ------------------MIESLVKVFSTVQ----VPIDWDVFH--EHKINSAEGEDVSPKLLESLCRNKIGIKGPFESGPC----------LRKLRKKFQLFAFVAVCRNLEG-----QNTRYGKLDCLIIRDQVEGEYSGIEHRVVPG----VMQTIKVSTAEGADRMARYVFEYAKKNNRKKITVAHKANIMRLTDGTFLSPMRREAAKYqdIMFEERYLDTVCLAMLMKPERKDVLVASSMYGDVLTFMAASIMGGPALCPGFAVGPMGL---IYEPIIHTNTNIAGKDIVNPTGMLLSGVLMLR-----EMKLNEYADKICCAVSTVFRedCRTKDLG------------------
160 UniRef50_B0BZF3 Isocitrate dehydrogenase NA... 237 5e-61 1 23.4% 18:342 12:325 -----------------ELGAQVTNALQMAIAATGVDITWQIVDIGG----EDQQGLLPNYIFDIIRTAKTAVIGPLMMPD------NYRQMEADIREKLDLYVNLRPAKTMVGIPSNY-----QNVDIMIVRETTEGIYAGIEFesGKRIREDAAVGIKPISVKGCGQIIEFAFNYARKTKRHQVIAVHQAHFMAHTDGLFLEIARDIAQEFPDIAFADRSIEVICQELMQKPERFDVLVMPNLYGDLLAHLCAGMVGGLSV-PIAHVGDKYAVFG----AQSTGTDDVGHD---PTSLILAGALMLRHLGE-----QEAAQRLQAAVEAVVASHvtTADL-------------------
161 UniRef50_P48735 Isocitrate dehydrogenase [N... 235 2e-60 1 16.7% 3:361 42:447 --KRIKVavVEMD--GDEMTRIIWQFIKEKLILPHVDIQLKYFDL-GLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDEARVEemWKSPNGTIRNILGGTVFREPI-ICKNIPRLVPGWTKP---ITIGRHAHGDQYKATDFVADRAGTFKMVFTPkyNTDESISGFAHSCFQYAIQ-KKWPLYMSTKNTILKAYDGRFKDIFQEidKHYkkIWYEHRLIDDMVAQVLKSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTI-EAEAAHGTVTRHyqKGrtNPIASIFAWTRGLEHRGKLdqDLIRFAQMLEKVCVETVESGAMTKDLAGclNTTDFLDTIKSNLDR
162 UniRef50_B1VH60 Putative dehydrogenase n=1 ... 234 5e-60 1 31.3% 3:350 5:337 --ETCRLGVWQGEGIGPEIVAPTVQAVELALQASGEATPEFVPLLLGREAINATGRIVPEETWETITGLDGWILGPHDNVSYPPSVAGQLNPSAHLRKQADLWANIRPVRGVPG-------AVHPDLDVVIVRENTEGMYADRNMLMGSGdnGEVSLAIGVFTQTKIRRIVRRA-AAIAAARDGVLTVAHKSNVLTETSGRYVAEAKACAEEF-GVEVQPVHIDALCAELVTRPERYATIVAENMFGDILSDLAGGLGGSLGIAGSINASESQ---VMAQAAHGSAPDIAGQGIANPAGIMNSAAQMLDSLGY-----PQAAELLEGAVREAVVKAP-TADLVREAAAAD-----------
163 UniRef50_D2SD16 Malate/L-lactate dehydrogen... 230 5e-59 1 27.1% 5:358 2:344 ----IRVALLPGDGVGEEVLDGPTRLLRLLAERGEVEVTGPWP--VGARAAAETGDVLPAGTLAACDAADAILLGAVGEDPRVPAgpRPEVALHRLRERYDLRISVREIPFADGRE------------LTVVRNLIGGSYGGADDRVLREDGSEAA-DVLRLTRERVAEVVHTACDVLGRRGGGRLVSVDKAN-LYATGRLWRQVAGDVARE-RGIEVEHRYVDRAAFELGSGAPVPDVLVTEGLLGDILSDLAAGRAGSPALCGSASLHprGRCVGLFEPAHGSAPRRALRDQVDPLGGFLALAALLRHF----PATREAGERVRAAVGAVLRSGPWTYDlgAAASTGQVADAVLAA---
164 UniRef50_C7YX79 Putative uncharacterized pr... 230 5e-59 1 21.6% 3:344 8:352 --RPFQVALLPGDGQGPYLASYVERTLDLIQrrRNVSFKVSRHDFGGVALAAGAGTALPSTTLGACRQSDAVLVCGCGDPRYG---IEPERGLLTLRQELEGCVNIRPVRFPSSqqSSYKPEVVEQLDITFFRDLTSGVYYGRRKEAGDDGE---AYDTTPYSRQTIERIARLAGTYAMqsPPKPVHSIDKHNVMATSRLWRSVVAHVFENEFPQVPLRHVLVDTASMILSSDPLSLniILTENMFGDILSDQAGGILGSPDVLASAAvgGSRGTPGIFEPFNLNP----GGKTVGPLGSIQAVGLMLE----LSLGLAAESEALSKAIRRTLdsDTRTVDLGG-----------------
165 UniRef50_P50217 Isocitrate dehydrogenase [N... 227 4e-58 1 16.4% 2:360 1:408 -MAFQKITvvEMD--GDEMTRVIWKSIKDKLILPFLELDIKYFSL-GLPHRDATDDKVTVESAEATQKYNVAIKCATITPDEARVKemWRSPNGTIRNILNGTVFREPI-MCKNIPRLVPGWTKP---ICIGRHAFGDQYRAteFEVYNFTGAGGVALSMYNTDESVRSFAEASMNMAFQ-KKWPLYLSTKNTILKKYDGRFKDIFQEVYeeEAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTI-EAEAAHGTVTRHygETSTNSIASIFAWTRGLAHRATLdeRLLDFTEKLEAACIGAVESGKMTKDLagslNTEEFIDAVADELK-
166 UniRef50_O75874 Isocitrate dehydrogenase [N... 226 1e-57 1 17.2% 1:360 1:406 MSKKIsvVEMQGD----EMTRIIWELIKEKLIFPYVELDLHSYDL-GIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEemWKSPNGTIRNILGGTVF-REAIICKNIPRLVSGWVKP---IIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQksIEDFAHSSFQMALSKG-WPLYLSTKNTILKKYDGRFKDIFQEidKQYkkIWYEHRLIDDMVAQAMKSEGGF-IWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTV-EAEAAHGTVTRHygQETsnPIASIFAWTRGLAHRAKLdkELAFFANALEEVSIETIEAGFMTKDLAayLNTFEFMDKLGENLK-
167 UniRef50_B6KL81 Isocitrate dehydrogenase, p... 222 2e-56 1 17.0% 3:361 180:583 --QRIKvpVVEMD--GDEMARVIWAMIKEKLILPYLDIPLMYYDL-SIQHRDKTDDQVTIDAALAIKRHGVGVKCATITPDEQRVKemWKSPNATIRNTLDGTIFRAPI-LMKNVPRLVPSWTKP---IIIGRHAHADQYKALdhEVYEFKGGGVALG-MYNTDASIKGFAHSCFQYALDQ-KMPLYLSTKNTVLKKYDGRFKDIFQTieKEYkgLWYEHRLIDDMVAQAIKSSGGF-VWACKNYDGDVQSDVVAQGYGSLGLMTSVLVCPDGKTI-EAEAAHGTVTRhyQKGitNPIASIYAWTRSLGHRAKLdqKLKEFVEALEDACVETVEAGFMTKDlgDKLttEDFMDKLARVAER
168 UniRef50_UPI00003C8595 isocitrate dehydrogenase n=... 222 2e-56 1 18.2% 2:359 21:374 -PDILTIGYIDGDGIGPEITGAMIGVVNSAIELagSRSIEWHKILIGTEAYEKFGTYVPEDSIKEIQKMYIAMK---STLNFMPDK---RDLNTILRKRLGLYSNIRILKYIEGMDIPVN--TFNRLNLTIIreSTDDLIRFISDNYGLNITPDSGIYMMPQSKFRTRKIAKQAVRYSRRNGKKKITILE-----SQQNHEFANWCIEEASAQEDVGYEVLKTREFMKRLISSPEDFEVILVDNVLSQTLVDYLA---GTINIEYGSSIGDE---CAVFEAVQSSLPSEAGYDAADPLSFILSGCEMLMHIG-----WVEAAQIIENAISAAFRDNKIPKDInsPIKCSEFSSEIIKRM--
169 UniRef50_A4FEJ6 3-isopropylmalate dehydroge... 212 1e-53 1 35.4% 7:252 9:253 ------IAVIPGDGIGPELVRSAVEVLRAAAGR-DVELRFTSED-AGADAFRRTGSAMSAATLERIrrYHGVLKGPVGLPGVrpDGTEAGLLGGVLRGGLDTYANVRPIALLPGVDAPLRGTA---VDYVIVRENTEGLYLSR----GRGVGNDRAcdQLLMTRHGVERVVVHAFELATRrgVRRVTCVDKSNVLR-SFAFFREVFDEVATRYPQVEADHRYADAAGHDLVADPGRFDVLVMENFLGDILSD-------------------------------------------------------------------------------------------------------------
170 UniRef50_Q0V3G8 Putative uncharacterized pr... 212 2e-53 1 16.4% 2:360 7:369 -MNKIKvpVVELD--GDEMTRIIWQVIKDKFIHPYLDIDLKYYDL-GLEYRDETNDQVTLDAAEAIKKYSVGVKCATITPDEQRVEemWLSPNGTIRNHLGGTVFRAPI-VIPAIPRLVPSWKQP---IIIGRHAFGDQYRAKDRVIDTEGTLEMVFTPKG-GKPEVIKVYDFPAevAQTQF--------KDIFQEIYEAQYRKEFEA-----AGIWYEHRLIDDMVAQMIKSEGGY-IIAMKNYDGDVQSDIVAQGFGSLGLMTSVLITPDGKTF-EAEAAHGTVTRHygRETsnPIASIYAWTQGLIKRGELdpELVVFAEQLEKACVDTveDGIMTKDLagkvTTNEYLDAVERRLK-
171 UniRef50_Q0CXI1 Isocitrate dehydrogenase, m... 212 2e-53 1 17.2% 36:360 90:459 -----------------------------------IPIQLPGHRPQGIEYRDQTDDKVTVEAAEAIKKYGVGVKCATITPDEARVEemWLSPNGTIRNILGGTVFREPI-VIPAIPRLVPGWTKP---IIIGRHAFGDQYRATDRVIPGPGKLELVYtsMYNTDDSIRGFAHSSFKMALLKG-LPLYMSTKNTILKRYDGRFKDIFQEieAEykGIWYEHRLIDDMVAQMIKSEGGF-IMALKNYDGDVQSDIVAQGFGSLGLMTSTLTTPDGSAFES-EAAHGTVTRHygRETsnPIASIFAWTRGLVQRGQLdpDVVTFAEELERACIEVveEGIMTKDLagrvTTREYMAAVERRLK-
172 UniRef50_Q9LQK9 Putative isocitrate dehydro... 205 2e-51 1 19.2% 1:360 1:294 MPRPVTV-------IDSNVTNAVHQVMDAMQA----PVYFETYIIKG-----KNMNHLTWEVVDSIRKNKVCLNGRVNNSLCGGA-----------RKELDLFASLVDCFNLNGQPS-----RHENVDIVVIRENTEGEYAGREHEVVPGVIESFQVTM---TKFWSDRIAKYAFEYAHFSKRKKVTAVHNNGKykLADAFFLESCQEVAKMYPNITYNEI-----ASRETRAIRRHS---NSKSLWAIIANIASGVAGG-------SFGDDY---AIFEQVGSVG------NHKNPVALLFSSVMMLRHL-----LLPLFADRLKTAVTRVISEGKCG---NSNTTTQEVVDSVIANLD-
173 UniRef50_B4PZH5 GE17383 n=3 Tax=Drosophila ... 199 1e-49 1 34.8% 196:359 112:268 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RMSDGLFLRCVRDMAQKFPEIQFEEKYLDTVCLNMVQNPGKYDVLVMPNLYGDILSDMCAGLVGGLGLTPSGNMGLNG---ALFESVHGTAPDIAGKDLANPTALLLSAVMMLRHM-----ELNTYADKIERAAFETIKEGklTGDLGGRAKCSEFTNEICAKL--
174 UniRef50_A1D5P0 Isocitrate dehydrogenase fa... 196 9e-49 1 19.7% 2:361 1:348 -MSSIQVGLAVGNGTGPELTAIFERVIQSLAARYNVSVTFLRSPRIYNSYSsnDADAVTEETLSDAAHYRQFCKEAVSCGVRAIFRTSISAQALYLVREQLQAIKVEHFTLSPTSS------------ILLVRDQAQGFYSGTN---SVNTSKDAVSRTAHFSKAIFARILSYALGRANQlgTNSVTMVYKFHLF---DGLFHTWATEWERTF-GVNIRFVQGDTMNRDLLagVSGHNLLISGNEYADIMQTILLDRFgeSACAENVYLHPDVQGLSEYQTAHGSADDLLGKGIVNPTATIRAAAAVLEDQAGCSG----LKQRVDCVLGDLGARGIGTPDQGGTATTERFVEAFLQGLDQ
175 UniRef50_B3MF82 GF11274 n=1 Tax=Drosophila ... 196 1e-48 1 18.3% 61:360 93:375 ------------------------------------------------------------DPLETDDFYNSVLRNRSAVHVENVVDAEAKKKSMKLCNDLDLYMFKCRVRSFPGF-----NCRFPDVNIRIIAQNNMGVYSDLEYSPVKG----VVEAISVSTQEGNEKYLRKAFATAVKANRKRVTLIHKSTEWPITDGAMVSAAKEIHKDYEhlELELMNVEDCIGRLITHPQEFDCIFSSDRYATMIATMCSGICGGANLFSAVEIGDFH---AVFKPLQ-VKLSLTNYPILSPYGIVNTIVDLFDHLGYT-----ECGDALWEQMLRTMESGIKTKDFGGEDSGEYVICNIINRLR-
176 UniRef50_B9SFA3 NADP-specific isocitrate de... 196 1e-48 1 13.7% 3:360 79:461 --DRVKvpIVEMD--GDEMTRVIWRMIKDKLIFPYLDLDIKYFDL-GILNRDATDDKVTVESAEATLKYNVAVKCATITPDETRVKemWRSPNGTIRNILNGTVFREPILCL-NIPRIVPGWKKP---ICIGRHAFGDQYRATDTLIKGPGKLKmgVALAMYNVDQSIrfAESSMSLAFA-KKWPLYLSTKNTILKKYDGRFKDIFQEVYEefEeiWYEHRLIDDMVAYAVKSEGGY-VWACKNYDGDLSSD-------GKTLEAEAAHGTVTRHFRLFQKGQETST--------NSIASIFAWTRGLEHRAKLdeGLLDFVHKLEGSCIETVEAGKMTKDLagplNTEEFIDAVAQNLE-
177 UniRef50_D0WIJ5 Isocitrate dehydrogenase, N... 194 4e-48 1 16.9% 1:360 33:431 MTkqMTTPLVEMD--GDEMTRIMWQMIKDELICPFVDLKTEYYDL-GLAHRDETDDQVTVDSAEATKRLGVAVKCATITPNAARVEemWKSPNGTIRAMLDGTVFRAPI-VVRGIDPCVKNWVRP---ITLARHAYGDVYRDAEMRIPGPGTVELVYtvHEFTEPgiESFARACFDFALATSQD-VWFATKDTISKTYDHRFKDIFQEiaARFegIEYFYTLIDDAVARVMKAEGGF-IWACKNYDGDVMSDMVSSAFGSLAMMTSVLASPHGYW--EYEAAHGTVQRHYYKHLanSVATIFAWTGALRKRAELdaDLAAFADALEQATVATIESGKMTGDLArkLSTGAFIKAVAEDLK-
178 UniRef50_A2Q9Q7 Contig An01c0300, complete ... 189 1e-46 1 19.8% 3:360 4:356 --QTVRLGLAVGHGTGRELVAVFERVIQTLAKQYSVNFEFVRSSSTYHSYhkNLITHIADETTKDAIDYQQFCENAAGSGIAAIFRTAIHAQSLYLVRQHLQAAKVEHFSLGDGNA------------LLMVRDEAQGFYAG---DNTYSADQLSITRTTSFSKPVFDRIIRFALDRAAEnvPKKVTMAYKFHLF---DGVFQAWEPQWKAQF-GIDFDFIQPDTLNRSLMAnvQGRCIIIAGNEYADVIQPVFLNWFGQStyAENVYLRPDVNGLSEYQTVHGSADAIADKGLVNPFATIRAAAAIlrHAGGKGIQ-----KLTEQAIQSLLQRKLTTPDQGGSLKTEETVDHFLQAIA-
179 UniRef50_B5DZV4 GA24694 n=6 Tax=Drosophila ... 188 2e-46 1 20.5% 69:360 110:384 --------------------------------------------------------------------FNSVLRNHAAVHVDILCDKEAKKKSLKICNDLDLYVFMTRLRSFPGFKC-----RFPDVDIQVIAQNNIGNYSELEYAPVKG----VVEALRVVTHENVTKYLRHAFEAAIRAGRCRVTLIHKANEWPVTDGAMVEIAEKmaEDYCSIKLELMELDDCVNRLITDPAYFDTIFTNDRYATFLATICSGVAGGANLFSAIELGDSH---AVFKPLQ-TKLSLTNYSLLSPYGIVSTCVDLLNHVGQES-----CAKSLWKGMLRTMTDGIKTVEFDGPDTGEYVICNIMNKLR-
180 UniRef50_C5FHL7 Isocitrate dehydrogenase fa... 188 4e-46 1 18.4% 2:359 4:355 -MDPLRIGVAIGHGTGPELATVFEHVVRELASRYSLGVEFVRSDRIYHSY---NSLPLADESQNATPDICDETVNDITHYQQFCEQEASRGLKVIFRTAIS-------AQSLYAVRQQLEAVKVECFdlLVIRDQAQGFYTGTNK---LESDQDSVSRVCHFRKGVFQHIIAFSLERAREkgIKSVFLVYKFHLF---DGLLLSWARDWTKEF-GIKVEFIQPDTMNRNLIAFGVHRCLMIAGNEYADIMQTIfnMRVQETSCSENVYLKPVLNRLSEYQTTHGSADDITGKGIVNPSATIRAAAAILERFGGCVG--------IDAKVDDTlkNKSGTPDQGGNLTTAAFVDVFLRTL--
181 UniRef50_B8BX37 Predicted protein n=1 Tax=T... 187 5e-46 1 16.7% 2:361 74:491 -SDKPKIKAPPMVYigEEMTHYATQLLLNQWIEPYFDISSWETFDLSCKARDDSDDATLIDAVEAGKRIGAIFKEPTITPSAIQVQEmwGSPNGAMRRGWNGITISRDTIHIEGIELGYKNQ------VLFERHAVGGEYGAGWNEVGEGtgAPFVVDKRDLTDknVRELAHLFFKRCLEHKVTP-YIVTKKTVFKWQEGFWATMKRVFDDTYKDeeLTHLISDAATMQLIRWTDGGFGMAAHNYDGDMLTDQIAQVHRSPGFITSNLVGVSDDGTTlfEASHGTVTdlAGKETsnPLGLVEagAMclEYDAKPNDVEAkfTNTLRMALHNTFRYGQGTRDMCGPttTEDFIAKVAWRLDR
182 UniRef50_A4SBK5 Predicted protein n=6 Tax=E... 184 4e-45 1 16.7% 6:359 7:409 -----KITAAPMVYvgEEMTAYVMDLIRAKWIEPRVDTTAWREFDLRAKNRDDTEDQVLRDVIEAGKAVKAIFKEPTVTPTADQvrKSWGSPNGAMRRGWNGITISRDTIHIDGVELGYKKPVFFE------RHAVGGEYAAGYKNVGKGtgKPVEVDSRTITDNevHELARFFFGRCLEAKITP-YVVTKKTVFKWQEPFWQIMKKVFDEEYkgDELVHLLSDAATMKLVQWRQGGFGMAAHNYDGDVLTDELAQIHKSPGFITSNLVGVDENGTLifEASHGTVAdlRGEETsnPLGMVEGLIGAMNHAADVheRTLAFTAKMRAVIHQLFREGKGTRDLSGplTTEQFVDAVAERL--
183 UniRef50_C7YNU4 Putative uncharacterized pr... 180 1e-43 1 20.8% 81:359 35:301 --------------------------------------------------------------------------------DGAPATSRPERGLLKLRKEMGTYGSMRPCFFASD---SLVAPQGRGVPRHRLCHCARAHRRYLLWRAQTGSG--SAWNTEPYSHAEVERFTHLAGFLTRGRGDKKLWSLDNANVLATSRFWRKVMTETFEKEFPDLKVEHQLINSAVMIMVKNPTGLnvVVTSTLFGDIISDAARVIPDSIGLLPSASldGNRKSNDIYEPIH--VLPLVSRARASSTPSARSC------------PWPCFSDTLSTSLRrvPPWSLRTKELGGGANTKELGEAVINEV--
184 UniRef50_A5B8K4 Putative uncharacterized pr... 173 7e-42 1 16.1% 8:360 66:474 -------PIVEMD--GDEMARIMWRMIKDKLIFPYLDLDIRYFDL-GILNRDATDDKVTVESAEATLKYNVAVKCATITPDEARVKemWRSPNGTIRNILNGTVFREPI-LCXNVPRIVPGWKKP---ICIGRHAFGDQYRATDTVVEGPGKLKLviALAMYNVDESIrfAESSMSLAFA-KKWPLYLSTKNTILKKYDG----------------RYEHRLIDDMVAYALKSDGGY-VWACKNYDGDVQSDLLAqfFGSYDfiSGKQLSSDGKTL-EAEAAHGTVTRhyQKGltNSIASIFAWTRGLEHRAKLdeRLLDFVHKLEAACIETVESGNMTKDLagplNTEEFIDTVAHNLE-
185 UniRef50_A8E541 Idh3a protein n=4 Tax=Eutel... 165 2e-39 1 35.9% 230:360 30:154 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGA--NGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMG-----LHGHAKKIETACFDTIRDKKvtKDLGGNPKCSEFTADICRRVQ-
186 UniRef50_A7T3D9 Predicted protein n=2 Tax=c... 157 6e-37 1 25.1% 2:184 26:225 -PNNPIIPFIEGDGIGIDISPVMIKVVDAAVQKAYgkISWMEVYAGEKATQvdQDTWLPQETLDAVKDYVVSIKGPLTTP----VGGGIRSLNVALRQQLDLYVCLRPVRWFEGVPSPVK--KPGDVDMTIFRENSEDIYAGIEWKAGSPedQDCGIGVKPVSKEGTKRLARKALHSAEAAVVK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
187 UniRef50_Q6L1Z1 Isocitrate dehydrogenase [N... 154 4e-36 1 17.8% 2:361 13:355 -PDDVTIGYIEGDGEGTELTRAMINAVNSAIeySGSKSIEWKKIYIGREAYEKYGKYLPRESIEDIRKTVFVMKGPLSS------NINGHDININIKRILNLYTDVKCITGLPGLssPSIDEVyeDSDMLR-------QYLQQSFNISIGGDSDIF--LKGTSRYRIIKIASKIAEISSLYGIKRTLVADDYTGSHA--PLW--VYNTLNKMEMPVEIENLY---NLYDEMTSESRFNIFIPDSRLSSLIIKIINART-----FFGAILGD---FISLFESQSRPSFTEEGYDLADPTSFLLASSMMLRRL-----NFNDAALILRNALNSVYSDGILPanLNNGLKCSDFIDAIVKRMKR
188 UniRef50_UPI00017440F3 Isocitrate dehydrogenase (N... 148 3e-34 1 25.3% 6:191 3:172 -----KITLIPGDGIGYEISESLVKIFDAAK----VPVEFET-ENAGSDVYEKTGELIPESLYESVERNKIAIKGPITTPI----GKGFRSINVYLRKKYDLYTNFRSSRNLPGIET-----RYDNIDLAIFRENTEGIYIGEEKYENEEKT--SAIAVKRITKKGSEELLKVLLNMQRIMEFRKLQLFIK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
189 UniRef50_Q7XZ87 Isocitrate dehydrogenase (F... 143 7e-33 1 24.7% 4:177 31:186 ---QFTVTLFPGHGVGPEISVAVQNIFNAA----DVPIVWDEHHID-VDNAKPGQDLISADALDSLRRNRFGLKGPMATPI----GKGYRSLNLTLRKALGLYANVRPCVSIPGVQTPY-----DDVDVVTVRENTEGEYSGLEHVVYPG----VVESLKVITPERVNARVQVPFSI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
190 UniRef50_B5G7Q5 Truncated isocitrate dehydr... 137 5e-31 1 20.2% 5:360 31:378 ----PTVGLAVGRGTGEEVAAVFTRVLGHLATRHERPVTLVRSPRVYHSYvePGGAGVPelSAEDAAHYEEWLRARARAGTRVVFRTAINAQSLYLVRQ-----RLRAVK--------VDTLDADGARLLLVRDEAQGFYTG-----GNTHTPGHVSRTTEFSREITEQLLAYALRRAREegPARIVMAYKFHLL---DGALDAWVRDFAAR-ENIEVGVFQPDTVNRNLVAHpeDRTVLLAGNEWADIMHLVLLDRYGSghCTRNVHLDPAVAELVEYQTVHGSADDLEGRDLLNPVATLRAAAAIarYVGCTGAEAATEAALARLAAAGV-----RTPDQGGKHSTTGVVDAFIEELG-
191 UniRef50_Q03UU7 3-isopropylmalate dehydroge... 129 1e-28 1 18.0% 5:265 2:256 ----YKLAILKGDKESSSVIDRALGIIKSSVNDS-TAFEVTELPF-GVNGVLSFNEPLPNQTLRELKNYDGILVGALNQEVGTDSLLSVQESLVALRKYLNITLACKAVQISDNnaSPLKNQIVRDTDFIIVQSAK----RANDHVDGNISVDDFAQDTITYEQREVEQVITAGFERAMNRKRA-VTVVTPFDSF-YTSKIWALTAEKIAKIYPDVVVNYVSLSCVISTIIQQPTSLDVVVAPKWVDQVLNEESQKITGLPETVP------------------------------------------------------------------------------------------------
192 UniRef50_Q8T494 AT08722p n=1 Tax=Drosophila... 129 2e-28 1 20.2% 138:360 2:212 -----------------------------------------------------------------------------------------------------------------------------------------GIFNELEYSPVEG----VVEALSVVSQKGNDKYLRYAFKAAAKAGRKRVTLINKAKEWPISDGSLVEAAQRLHCHYKdlELELMEVEEAISRLMTEPTYFDCLFASERYATFLSAICSGVCGGANLFSAVEIGDHH---AVFKPLQ---TKLSLTNYAnaYGIVSTIVDLFQHLGH-----DKCADALWCELKRTMNEGIRTKEFGGQDTGEYVICNIINQLR-
193 UniRef50_B1XUL5 Tartrate dehydrogenase n=1 ... 121 3e-26 1 54.2% 242:359 1:120 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPNVFGDILSDLGPACTGTIAVAPSGSINPEGKFPSLFEPVHGSTPDIFGKMIANPIGqfGVGAMILDHLGY-----PETGKAIFSVIEKVLSSgpLTPDLGGSAKTDDLGKAIAAAI--
194 UniRef50_A3JDN6 Isocitrate dehydrogenase n=... 116 1e-24 1 24.5% 157:360 355:578 ------------------------------------------------------------------------------------------------------------------------------------------------------------ILLMSNDHEAIKDWVSQVFRDASS-KHKEVYFGLKREYMEYDEVfiNDVRRELAADhsPPAFMIMRPSSQLIKMITDPPRSALYPAQNLDGDIFSDISAALGGSLATASS--IIESKSSTMLFEAPHGTAHDLYLKYLenPSALIYALANALETLgeRNEALLDYSARLKAALKDTVGDGIVTADLKDKTTTPefLDSIEKRLG-
195 UniRef50_B8KHT3 Isocitrate dehydrogenase, N... 113 1e-23 1 23.2% 142:361 341:579 ---------------------------------------------------------------------------------------------------------------------------------------------GEEKHARTVKSNDP-ILFMSNDRESIKDWVKQVFRDAALY-KKEVYFGLKrnYDEVYSSIILEIRKELAadTPPPSFMIMRPSRQLSKMICDPPRWGLYPAQNLDGDIFSDISAALGGSLATASSVIKSKDGTL--LFEAPHGTAHDLYLRYLenSSALIFAVANALEELARReaPLAEYAEALKAALIETVAQGTITGDLKGKTLAPefLDAIESNLNK
196 UniRef50_A5BNI3 Putative uncharacterized pr... 113 1e-23 1 29.5% 2:113 40:152 -PKRYSITLLPGDGIGPEVISVAKNVLKLAGSLEGIEFGFQEMPVGGC-ALDLTGVPLPEETLLVAKQSDAVLLGAIGGYKWdeKHLKPETGLLQLRSGLKVFANLRPASVLP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
197 UniRef50_B6QRT7 3-isopropylmalate dehydroge... 107 7e-22 1 18.4% 1:158 1:156 MAEIRKLLVLRGDRIGPEIIAEALKPLTVLveRPDFKVQVRYGLLAGAS-LDKTNEPITDKVLDAALATDAVLLGSVGEPEWapGALNPEKGILRLRQRLDAFANIRPCRFCASsqSPLKSDMVNGV-------NFGEQYAARSRSTGGCCTKDIGLA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
198 UniRef50_Q8N9Z6 cDNA FLJ36019 fis, clone TE... 107 8e-22 1 27.0% 96:206 2:103 -----------------------------------------------------------------------------------------------LHTTLDLYASVIHLKNLPNVET-----WHKDVDILVVWENTEGEYSNLEHESVKGVTE----SLKIMTKAKSLRIAEYAFQLAQKMGCKKVMAVHKVNITKLGDGPFLQCC-----------------------------------------------------------------------------------------------------------------------------------------------------------
199 UniRef50_B8ARP0 Putative uncharacterized pr... 105 4e-21 1 16.8% 86:258 28:222 -------------------------------------------------------------------------------------KSMWRSPNGTIRNILNGTVFREPI-LCKNVPRILSGWKKP---ICIGRHAFGDQYRATDTIINGPGKLKMvvALSMYNVDESIrfAESSMAMALS-KKWPLYLSTKNTILKKYDGRFKDIFQEvkFEENSIWYEHRLIDDMVAYAVKSEGGY-VWACKNYDGDVQSDFLAQIF-------------------------------------------------------------------------------------------------------
200 UniRef50_Q567A6 Isocitrate dehydrogenase 3 ... 99 2e-19 1 20.1% 4:137 50:168 ---RHTVTLIPGDGIGPELLNHVRELFRFSC----VPVDFEVVHVNSSSTSEDDIS----NAIMAIRRNGVALKGNIETNHTMPP--NHKSRNNLLRTSLDLYANVMHCQSLPGVQT-----RHKNIDIIIILEKSE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
201 UniRef50_C7GAF7 3-isopropylmalate dehydroge... 96 2e-18 1 27.1% 6:112 4:115 -----KIGVISGDGIGPEIVAEAKKVLDKIGTKYGHSFLYEAILMGGCS-IDATGVPLTDEAIAAAKASDAVLMGSIGGNTATSPwlRPEAGLLKLRKSLNLFANLRPAYLY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
202 UniRef50_B5KE47 4-hydroxythreonine-4-phosph... 90 8e-17 1 17.9% 2:309 6:329 -MTKPKIAIIPGdgIGPELIAQLlgVSEAaaRQAGVRLQLDPIAWANLAEF----SGLRQLEMETIDVADV--------KVAEVTIQSGKSALRTLDQALDLAviVDGVLFGPFNKAALTAAGL----------NAEDeyLGFKGYHSEVNVLDDLMTTRviTADGVRKAIMMAHDTLAKAGKSRPHVAVAanPHAGDNGKfrEEIDILAPVVAEYQGRHMHVssDTVFLKAKAGEVDAVVT--MYHD-QGQIAIKLMggVTVAGGLPI-------PVVTPAHGTAFDIAGQSVANVGATRNAFNLLLR----------------------------------------------------
203 UniRef50_Q7X199 Lfe195p1 (Fragment) n=4 Tax... 85 3e-15 1 35.4% 282:360 4:78 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VHGSAPKYAGMKKVNPSAVLLSGVMMLKWLNE-----HEAATRIEKGVDKVLAEAKhtYDAGGTASTDEYADAIIKAMG-
204 UniRef50_Q8KH40 LeuB (Fragment) n=3 Tax=Buc... 85 3e-15 1 34.9% 279:361 11:93 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YEPAGGSAPDIAGKNIANPIAQILSIAMLVRY----TMKLPIISDQIESAVIDTLKKGYRTLDIANDksTNDIGDIISYILKK
205 UniRef50_C1GSN2 3-isopropylmalate dehydroge... 85 5e-15 1 25.5% 2:103 360:462 -MTTHTILVLRGDGIGLEITAEAVKVL-SAFSLKKRTFDLRSELIDGCS-IDTDGTPITKTVIQAALDSDAVLFASVGGPKWDgdLEGPEGGLLQLRKAMNQW------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
206 UniRef50_A3RRN5 Tartrate dehydrogenase n=3 ... 82 4e-14 1 53.7% 2:83 1:82 -MSSYRIAVIPGDGIGKEAVPERLRVPDAAARRFGFALHCGHFDFASSDTRARHGKLRPDDRFDTLRGYDALFFGAVGRPDTG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
207 UniRef50_Q1G324 Putative uncharacterized pr... 79 2e-13 1 34.6% 3:80 39:115 --KRYTIAVLPGDGVGNEVIPVAVDVLCLAGSLEGIDFSFEELPIGGV-ALDLVGVPLPKETLIRAKQSDALLLGAVGWY-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
208 UniRef50_Q4V533 IP13250p (Fragment) n=8 Tax... 77 1e-12 1 24.8% 61:189 99:218 ------------------------------------------------------------EAGQDDEYFHSVLRNRTAVHVDNQADAEAKQKALKICNDLDLYVFKTRTRSFPGFKC-----RFPGVDIQLIGQNNMGIFNELEYSPVEG----VVEALSVVSQKGNDKYLRYAFKAAAKAGRKRVTLI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
209 UniRef50_Q84AT8 LeuB (Fragment) n=1 Tax=Buc... 77 1e-12 1 34.6% 284:361 2:79 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GSAPDIAGKNIANPIAQILSIAMLVRY----TMKLHKIADDIESSVIDALKKGYKTLDIAnhISTSDMGDVISNILNK
210 UniRef50_UPI0001792E94 PREDICTED: similar to AGAP0... 76 2e-12 1 34.8% 294:359 155:216 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IANPTAMLMCASKMLRHV-----NLQHYSESIRNAIREVLAAGkrTRDLGGSSSTHEFTDAVIKAI--
211 UniRef50_B6QD56 Putative uncharacterized pr... 75 3e-12 1 42.3% 3:80 7:84 --KTYKIASIPGDDIGPEVVNVIIDVLKSLQelSTYRLEFTELDW-GTARYKRTGKYMPADGLSTLKTFHAGIFGAVGAP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
212 UniRef50_Q11SB4 Putative uncharacterized pr... 70 1e-10 1 34.2% 281:359 209:284 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PMHGHAPDIVGMGIANPYALLMAFCRLLTVAGYEELAQQVE-NQIESAFYE--NRDQTTPDQGGVLNTEKYMAMMVECI--
213 UniRef50_B5X9F9 Isocitrate dehydrogenase, m... 68 4e-10 1 11.3% 3:108 42:151 --KRIKvpVVEMD--GDEMTRIIWEFIKEKLILSNVDVELKYYDL-GLPYRDQTDDQVTIDSAIATQKYHVAVKCATITPDEQRVEemWKSPNGTIRNILGGTVFREP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
214 UniRef50_B8P335 Predicted protein (Fragment... 68 7e-10 1 21.1% 5:80 9:77 ----YTVTLIPGDGIGNEITDSVKEIFEYV----NAPIEWEQYNVSGMSSA---GEDLFKQAVESLRRNRVGLKGILFTP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
215 UniRef50_A8PW52 Probable isocitrate dehydro... 67 7e-10 1 19.5% 6:82 27:98 -----RVTLIPGDGIGPEISSSVQKIFEAA----NAPIEWDPVDVTPVKGDDGIFR-IPSKCIELMRINKIGLKGPLATPNW---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
216 UniRef50_Q5D5H6 Isocitrate dehydrogenase, N... 67 9e-10 1 24.6% 293:361 6:75 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NIANPSGLLNAAVHMLIYIGQVGT-----AKLIYDAWLKTLEGGIHTADLYkkVGTKEFAEAVIDNLGK
217 UniRef50_D0DDP2 3-isopropylmalate dehydroge... 66 2e-09 1 44.8% 278:335 1:59 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFEPAHGSAPDIAGRNIANPIAAIWSGAQMlrHRGGHRAGHRHPSAAGHGANKAVMID--------------------------
218 UniRef50_Q0ZQ47 FrbB n=1 Tax=Streptomyces r... 63 1e-08 1 16.3% 149:246 139:239 ----------------------------------------------------------------------------------------------------------------------------------------------------REIPEQAALGIQAIAPDRVSEFVRTAVGMCRRLDVDDLVVAHKGNSIKHTDGLFALTAAETLESlaGIAWRSLIIDHMAAELVRNPLDYRAILTHSSF-------------------------------------------------------------------------------------------------------------------
219 UniRef50_UPI0001AF5761 3-isopropylmalate dehydroge... 61 5e-08 1 30.9% 1:55 8:59 MSKQ--ILILPGDGIGPEIMTEAVKVLELANEKYQLGFEL-THDVIGGAAIDKHG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
220 UniRef50_P56472 Isocitrate dehydrogenase [N... 61 6e-08 1 26.2% 253:359 25:100 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VGPELMAAVGVIECLKLGDGLFLQCCEE-----VAELYPKNIANPTATLLASCMMLDHL--------------------------KTSDMGGYATCQDFTEAVIGAL--
221 UniRef50_C6HDM5 Predicted protein n=1 Tax=A... 61 7e-08 1 29.0% 116:208 80:162 -------------------------------------------------------------------------------------------------------------------RSSLRGCQPRGFNWVIVPENPEGEYSGHSGRSHASKLWEMLITSG---------LSKIAYQLLRG-PEKHIAIATKSNAQRNGLVIWNEVAAE---------------------------------------------------------------------------------------------------------------------------------------------------------
222 UniRef50_Q566P0 Zgc:113076 protein n=6 Tax=... 56 2e-06 1 29.5% 300:360 1:57 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLLASCLMLDHL-----KLHDYANMIRSAILTTMNerLHTVDIGGQGTTSEVVQSIMRIIQ-
223 UniRef50_P56471 Isocitrate dehydrogenase [N... 55 5e-06 1 19.7% 6:76 6:72 -----TVTLIPGDGIGPEISAAVMKIFDAAKA----PIQANVRPCVSIEGYKFNEMYLDTVCLNIETACFATIKCS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
224 UniRef50_Q4VCC2 Isocitrate dehydrogenase (F... 53 1e-05 1 14.1% 163:226 1:70 ------------------------------------------------------------------------------------------------------------------------------------------------------------------TDESIYSFAEASMTTAYE-KKWPLYLSTKNTILKKYDGRFKDIFQEVYeeAAGIWYEHRLIDDM---------------------------------------------------------------------------------------------------------------------------------------
225 UniRef50_B5E4Z3 3-isopropylmalate dehydroge... 53 1e-05 1 36.4% 6:49 4:47 -----KIVALAGDGIGPEIMEVGLEVLEALAEKTGFDYEIDRRPFGGAD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
226 UniRef50_Q9H302 NADP+-specific isocitrate d... 52 4e-05 1 21.5% 296:360 6:84 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NPIASIFAWTRGLALRAKTdkELAFFANALEEVCIETIEAGFMTKDLAayLNTFEFMEKLGENLK-
227 UniRef50_D1Z545 Whole genome shotgun sequen... 51 6e-05 1 16.2% 181:217 75:111 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RVEEKVTCIHKANIMKLADGLFHGTFNRLAKDFPQLE------------------------------------------------------------------------------------------------------------------------------------------------
228 UniRef50_D2H627 Putative uncharacterized pr... 48 5e-04 1 13.7% 48:120 106:185 -----------------------------------------------IENHDATNDQVTKDAAEAIKKYNAGVKCAAITPDEKRVEemWKSPNGTIRNILGGTVFREacKNIPRLASDVR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
229 UniRef50_A5LXH0 Putative uncharacterized pr... 47 0.001 1 50.0% 6:33 4:31 -----KIVALVGDGIGPEIMEAGLEVLEALAEK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
230 UniRef50_C5K691 Nadp-specific isocitrate de... 46 0.002 1 23.2% 292:360 3:85 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KTSTNPIASIFAWSRALNQRAILdsRLKHFAQALEEACIESVEAGYMSKDlaGtlTSEDLIDYFSERLK-
231 UniRef50_UPI0001AF257B hypothetical protein SrosN1... 46 0.003 1 16.0% 188:349 1:168 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTHKGNSIKYTDGLFAVVAKQELEKlsGIIQESLIIDHMAAELTRNPQDYRAILTHglDGQLDTD-AGGVCRTIGTARRPLFGYD---VALDPARHTRAPEAEAAGRLRSV--LLAGSLLADHLDQGVAAAGIRAAADALDAPATADGHAGTAGLAACARTA------------
232 UniRef50_Q9SF26 Putative dehydrogenase n=1 ... 45 0.003 1 22.2% 2:46 41:81 -STPIKATLFPGDGIGPEIAESVKQVFTAA----DVVIDWDEQFVG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
233 UniRef50_Q1M832 Putative uncharacterized pr... 44 0.007 1 25.5% 310:360 39:85 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HVGEGEK-----ANAIRNAVEKVLndNVRTGGLGGSATTKEFTAATERRLA-
234 UniRef50_C0BPH4 3-isopropylmalate dehydroge... 44 0.008 1 23.0% 273:359 2:83 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GIGINLFEPLEDSQSTL--KEKVNPIPLIYSLALLLSRFG-----LQEEAGAIQMAVNSAGERgyTTLdlPKDINCDQLGDYLAAAI--
235 UniRef50_Q2VF40 Isocitrate dehydrogenase 3 ... 43 0.022 1 36.0% 4:28 112:136 ---RHTVTMIPGDGIGPELMLHVKSVFR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
236 UniRef50_A7IS87 LeuB (Fragment) n=1 Tax=Nei... 42 0.029 1 32.6% 2:47 1:44 -MTKH-IAILRGDGIGSEIVAETVRVLDKLIAQ-GLDAGYEYAPLGG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
237 UniRef50_Q9I1Q5 4-hydroxythreonine-4-phosph... 42 0.037 1 19.3% 166:310 190:335 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------EAIRLIDDALRRslARPRIGVCGLNPHNGDNGSFG--REELDIIaaREQGIAAdpYPADTIFLKVQGDARAFDAVVT--MYHD-QGQIAIKLMgsRGVTVQG-----GLPIPIATPAHGTAFDIAGQGRADVGATRQaaCRMGRH---------------------------------------------------
238 UniRef50_Q1Q0V0 Similar to pyridoxal phosph... 41 0.053 1 51.9% 281:307 310:339 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PDHGTAYDIAGKGIANPDSmiMTAIMM------------------------------------------------------
consensus/100% .........................................................................................................................................................................................................................................................................................................................................................................
consensus/90% .........................................................................................................................................................................................................................................................................................................................................................................
consensus/80% .....l.hh.hp..G.ph...h..hht.........h...........................h.t.thhhhs.h..................hp..ht.h..h..h...................h.hhh....s.a......................t.....ph.p.shths.......h....c.t........h.............h.......p.....h........hhh..s..tsh.t.......t...h................ps.ttsh..h...thhsP.u.h.s...hht............t..h...h...h..t..s.t..t..ts..h..........
consensus/70% ....plshl.GDGlG.Elh.tshplhp.h.....h.hth..h...s.t...t.tt.hs.pshpthtt.pshlhushtt...........t..h.lRpthshasthcshh.h.t............hshhhhRc.hts.Y.s..h.........hs.t.t.hop.t.t+hhchuhphA.tt..tplh.hpKsshht.s..ha.phhtthttph.tl.hp..hhDshhh.hh.pstthplhhh.Nh.GDllss.ss.h.Guhuhhsuhphs.......hhcsh+uou.phhspshsNPhu.lhuhshhLpah..........uthl.tuh.tshttt.hT.Dhss.htstthhp.lht.h.
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