Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	V	E	L	K	E	P	L	A	T	L	W	R	G	K	D	A	F	A	E	V	K	K	L	N	G	E	V	F	R	E	L	E	T	R	R	T	L	R	F	E	L	S	G	K	S	Y	F	L	K	W	H	K	G	T	T	L	K	E	I
Secondary structure
SS confidence
Disorder		?	?	?	?	?																					?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		I	K	N	L	L	S	L	R	M	P	V	L	G	A	D	R	E	W	H	A	I	H	R	L	S	D	V	G	V	D	T	M	K	G	I	G	F	G	E	K	G	L	N	P	L	T	R	A	S	F	I	I	T	E	D	L	T	P	T	I
Secondary structure
SS confidence
Disorder							?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		S	L	E	D	Y	C	A	D	W	A	V	N	P	P	D	I	R	V	K	R	M	L	I	A	R	V	A	T	M	V	R	K	M	H	T	A	G	I	N	H	R	D	C	Y	I	C	H	F	L	L	H	L	P	F	T	G	R	E	D	E
Secondary structure
SS confidence
Disorder												?	?	?	?	?																																								?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		L	K	I	S	V	I	D	L	H	R	A	Q	I	R	A	K	V	P	R	R	W	R	D	K	D	L	I	G	L	Y	F	S	S	M	N	I	G	L	T	Q	R	D	I	W	R	F	M	K	V	Y	F	G	M	P	L	R	K	I	L	S
Secondary structure
SS confidence
Disorder													?	?	?	?		?	?																																					?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.
Sequence		L	E	Q	N	L	L	N	M	A	S	V	K	A	E	R	I	K	E	R	T	Q	R	K	G	L
Secondary structure
SS confidence
Disorder		?	?																				?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3qa8 chain A Region: 22 - 231 Aligned: 186 Modelled: 210 Confidence: 100.0% Identity: 14% PDB header:immune system, signaling protein Chain: A: PDB Molecule:mgc80376 protein; PDBTitle: crystal structure of inhibitor of kappa b kinase beta Phyre2 PDB 2acx chain B Region: 14 - 255 Aligned: 212 Modelled: 234 Confidence: 99.9% Identity: 17% PDB header:transferase Chain: B: PDB Molecule:g protein-coupled receptor kinase 6; PDBTitle: crystal structure of g protein coupled receptor kinase 6 bound to2 amppnp Phyre2 PDB 3c4y chain A Region: 14 - 231 Aligned: 191 Modelled: 199 Confidence: 99.9% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:rhodopsin kinase; PDBTitle: crystal structure of apo form of g protein coupled receptor kinase 12 at 7.51a Phyre2 PDB 3pfq chain A Region: 16 - 231 Aligned: 186 Modelled: 208 Confidence: 99.9% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:protein kinase c beta type; PDBTitle: crystal structure and allosteric activation of protein kinase c beta2 ii Phyre2 PDB 2fo0 chain A Region: 31 - 231 Aligned: 186 Modelled: 201 Confidence: 99.9% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform); PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase Phyre2 PDB 1ym7 chain C Region: 16 - 231 Aligned: 185 Modelled: 198 Confidence: 99.9% Identity: 16% PDB header:transferase Chain: C: PDB Molecule:beta-adrenergic receptor kinase 1; PDBTitle: g protein-coupled receptor kinase 2 (grk2) Phyre2 PDB 2pzi chain A Region: 26 - 231 Aligned: 166 Modelled: 200 Confidence: 99.9% Identity: 14% PDB header:transferase Chain: A: PDB Molecule:probable serine/threonine-protein kinase pkng; PDBTitle: crystal structure of protein kinase pkng from mycobacterium2 tuberculosis in complex with tetrahydrobenzothiophene ax20017 Phyre2 PDB 1opl chain A Region: 31 - 231 Aligned: 186 Modelled: 201 Confidence: 99.9% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase; PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase Phyre2 PDB 3soa chain A Region: 16 - 231 Aligned: 184 Modelled: 207 Confidence: 99.9% Identity: 14% PDB header:transferase/transferase inhibitor Chain: A: PDB Molecule:calcium/calmodulin-dependent protein kinase type ii subunit PDBTitle: full-length human camkii Phyre2 PDB 3fbv chain L Region: 24 - 231 Aligned: 185 Modelled: 194 Confidence: 99.9% Identity: 17% PDB header:transferase, hydrolase Chain: L: PDB Molecule:serine/threonine-protein kinase/endoribonuclease ire1; PDBTitle: crystal structure of the oligomer formed by the kinase-ribonuclease2 domain of ire1 Phyre2 PDB 2j0k chain B Region: 26 - 231 Aligned: 165 Modelled: 185 Confidence: 99.9% Identity: 13% PDB header:transferase Chain: B: PDB Molecule:focal adhesion kinase 1; PDBTitle: crystal structure of a fragment of focal adhesion kinase2 containing the ferm and kinase domains. Phyre2 PDB 3ckx chain A Region: 14 - 254 Aligned: 206 Modelled: 238 Confidence: 99.9% Identity: 14% PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase 24; PDBTitle: crystal structure of sterile 20-like kinase 3 (mst3, stk24)2 in complex with staurosporine Phyre2 PDB 2h8h chain A Region: 31 - 231 Aligned: 185 Modelled: 194 Confidence: 99.9% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: src kinase in complex with a quinazoline inhibitor Phyre2 PDB 1k9a chain B Region: 14 - 231 Aligned: 176 Modelled: 188 Confidence: 99.9% Identity: 12% PDB header:transferase Chain: B: PDB Molecule:carboxyl-terminal src kinase; PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution Phyre2 PDB 3q5i chain A Region: 40 - 231 Aligned: 176 Modelled: 192 Confidence: 99.9% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:protein kinase; PDBTitle: crystal structure of pbanka_031420 Phyre2 PDB 2vwi chain C Region: 14 - 254 Aligned: 212 Modelled: 231 Confidence: 99.9% Identity: 13% PDB header:transferase Chain: C: PDB Molecule:serine/threonine-protein kinase osr1; PDBTitle: structure of the osr1 kinase, a hypertension drug target Phyre2 PDB 2ozo chain A Region: 26 - 231 Aligned: 167 Modelled: 177 Confidence: 99.9% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: autoinhibited intact human zap-70 Phyre2 PDB 2buj chain A Region: 14 - 231 Aligned: 198 Modelled: 210 Confidence: 99.9% Identity: 14% PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase 16; PDBTitle: crystal structure of the human serine-threonine kinase 162 in complex with staurosporine Phyre2 PDB 1y57 chain A Region: 31 - 231 Aligned: 185 Modelled: 194 Confidence: 99.9% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor Phyre2 PDB 1koa chain A Region: 16 - 231 Aligned: 186 Modelled: 208 Confidence: 99.9% Identity: 12% PDB header:kinase Chain: A: PDB Molecule:twitchin; PDBTitle: twitchin kinase fragment (c.elegans), autoregulated protein2 kinase and immunoglobulin domains Phyre2 1 c3qa8A_ 2 c2acxB_ 3 c3c4yA_ 4 c3pfqA_ 5 c2fo0A_ 6 c1ym7C_ 7 c2pziA_ 8 c1oplA_ 9 c3soaA_ 10 c3fbvL_ 11 c2j0kB_ 12 c3ckxA_ 13 c2h8hA_ 14 c1k9aB_ 15 c3q5iA_ 16 c2vwiC_ 17 c2ozoA_ 18 c2bujA_ 19 c1y57A_ 20 c1koaA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3qa8A_ 100.0 14 PDB header:immune system, signaling protein Chain: A: PDB Molecule:mgc80376 protein; PDBTitle: crystal structure of inhibitor of kappa b kinase beta 2 c2acxB_ 99.9 17 PDB header:transferase Chain: B: PDB Molecule:g protein-coupled receptor kinase 6; PDBTitle: crystal structure of g protein coupled receptor kinase 6 bound to2 amppnp 3 c3c4yA_ 99.9 18 PDB header:transferase Chain: A: PDB Molecule:rhodopsin kinase; PDBTitle: crystal structure of apo form of g protein coupled receptor kinase 12 at 7.51a 4 c3pfqA_ 99.9 13 PDB header:transferase Chain: A: PDB Molecule:protein kinase c beta type; PDBTitle: crystal structure and allosteric activation of protein kinase c beta2 ii 5 c2fo0A_ 99.9 13 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform); PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase 6 c1ym7C_ 99.9 16 PDB header:transferase Chain: C: PDB Molecule:beta-adrenergic receptor kinase 1; PDBTitle: g protein-coupled receptor kinase 2 (grk2) 7 c2pziA_ 99.9 14 PDB header:transferase Chain: A: PDB Molecule:probable serine/threonine-protein kinase pkng; PDBTitle: crystal structure of protein kinase pkng from mycobacterium2 tuberculosis in complex with tetrahydrobenzothiophene ax20017 8 c1oplA_ 99.9 13 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase; PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase 9 c3soaA_ 99.9 14 PDB header:transferase/transferase inhibitor Chain: A: PDB Molecule:calcium/calmodulin-dependent protein kinase type ii subunit PDBTitle: full-length human camkii 10 c3fbvL_ 99.9 17 PDB header:transferase, hydrolase Chain: L: PDB Molecule:serine/threonine-protein kinase/endoribonuclease ire1; PDBTitle: crystal structure of the oligomer formed by the kinase-ribonuclease2 domain of ire1 11 c2j0kB_ 99.9 13 PDB header:transferase Chain: B: PDB Molecule:focal adhesion kinase 1; PDBTitle: crystal structure of a fragment of focal adhesion kinase2 containing the ferm and kinase domains. 12 c3ckxA_ 99.9 14 PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase 24; PDBTitle: crystal structure of sterile 20-like kinase 3 (mst3, stk24)2 in complex with staurosporine 13 c2h8hA_ 99.9 16 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: src kinase in complex with a quinazoline inhibitor 14 c1k9aB_ 99.9 12 PDB header:transferase Chain: B: PDB Molecule:carboxyl-terminal src kinase; PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution 15 c3q5iA_ 99.9 13 PDB header:transferase Chain: A: PDB Molecule:protein kinase; PDBTitle: crystal structure of pbanka_031420 16 c2vwiC_ 99.9 13 PDB header:transferase Chain: C: PDB Molecule:serine/threonine-protein kinase osr1; PDBTitle: structure of the osr1 kinase, a hypertension drug target 17 c2ozoA_ 99.9 13 PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: autoinhibited intact human zap-70 18 c2bujA_ 99.9 14 PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase 16; PDBTitle: crystal structure of the human serine-threonine kinase 162 in complex with staurosporine 19 c1y57A_ 99.9 16 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor 20 c1koaA_ 99.9 12 PDB header:kinase Chain: A: PDB Molecule:twitchin; PDBTitle: twitchin kinase fragment (c.elegans), autoregulated protein2 kinase and immunoglobulin domains 21 c3byvA_ not modelled 99.8 12 PDB header:transferase Chain: A: PDB Molecule:rhoptry kinase; PDBTitle: crystal structure of toxoplasma gondii specific rhoptry2 antigen kinase domain 22 c3q60A_ not modelled 99.8 10 PDB header:transferase Chain: A: PDB Molecule:rop5b; PDBTitle: crystal structure of virulent allele rop5b pseudokinase domain bound2 to atp 23 c3e7eA_ not modelled 99.8 14 PDB header:transferase Chain: A: PDB Molecule:mitotic checkpoint serine/threonine-protein kinase bub1; PDBTitle: structure and substrate recruitment of the human spindle checkpoint2 kinase bub 24 c2c30A_ not modelled 99.8 17 PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase pak 6; PDBTitle: crystal structure of the human p21-activated kinase 6 25 c3p23B_ not modelled 99.8 18 PDB header:hydrolase, transferase Chain: B: PDB Molecule:serine/threonine-protein kinase/endoribonuclease ire1; PDBTitle: crystal structure of the human kinase and rnase domains in complex2 with adp 26 c2vuwA_ not modelled 99.8 14 PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase haspin; PDBTitle: structure of human haspin kinase domain 27 d1qcfa3 not modelled 99.8 15 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 28 d2j4za1 not modelled 99.8 15 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 29 c3lijA_ not modelled 99.8 15 PDB header:transferase Chain: A: PDB Molecule:calcium/calmodulin dependent protein kinase with PDBTitle: crystal structure of full length cpcdpk3 (cgd5_820) in2 complex with ca2+ and amppnp 30 c2wtkC_ not modelled 99.8 13 PDB header:transferase/metal-binding protein Chain: C: PDB Molecule:serine/threonine-protein kinase 11; PDBTitle: structure of the heterotrimeric lkb1-stradalpha-mo25alpha2 complex 31 c2a1aB_ not modelled 99.8 16 PDB header:protein synthesis/transferase Chain: B: PDB Molecule:interferon-induced, double-stranded rna-activated protein PDBTitle: pkr kinase domain-eif2alpha complex 32 c2jiiA_ not modelled 99.8 10 PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase vrk3 molecule: vaccinia PDBTitle: structure of vaccinia related kinase 3 33 c3d9vA_ not modelled 99.8 15 PDB header:transferase Chain: A: PDB Molecule:rho-associated protein kinase 1; PDBTitle: crystal structure of rock i bound to h-1152p a di-2 methylated variant of fasudil 34 c2c0iA_ not modelled 99.8 17 PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983 35 c2v62A_ not modelled 99.8 13 PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase vrk2; PDBTitle: structure of vaccinia-related kinase 2 36 c3en9B_ not modelled 99.8 18 PDB header:hydrolase Chain: B: PDB Molecule:o-sialoglycoprotein endopeptidase/protein kinase; PDBTitle: structure of the methanococcus jannaschii kae1-bud32 fusion2 protein 37 c2zv2A_ not modelled 99.8 14 PDB header:transferase/transferase inhibitor Chain: A: PDB Molecule:calcium/calmodulin-dependent protein kinase kinase 2; PDBTitle: crystal structure of human calcium/calmodulin-dependent protein kinase2 kinase 2, beta, camkk2 kinase domain in complex with sto-609 38 c3op5B_ not modelled 99.8 13 PDB header:transferase Chain: B: PDB Molecule:serine/threonine-protein kinase vrk1; PDBTitle: human vaccinia-related kinase 1 39 d1opja_ not modelled 99.8 14 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 40 d1yhwa1 not modelled 99.8 13 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 41 c2c47D_ not modelled 99.8 21 PDB header:transferase Chain: D: PDB Molecule:casein kinase 1 gamma 2 isoform; PDBTitle: structure of casein kinase 1 gamma 2 42 c2y7jB_ not modelled 99.8 18 PDB header:transferase Chain: B: PDB Molecule:phosphorylase b kinase gamma catalytic chain, PDBTitle: structure of human phosphorylase kinase, gamma 2 43 d1phka_ not modelled 99.8 17 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 44 c3rp9A_ not modelled 99.8 15 PDB header:transferase Chain: A: PDB Molecule:mitogen-activated protein kinase; PDBTitle: crystal structure of the apo mapk from toxoplasma gondii, 25.m01780 or2 tgme49_007820 45 c3comB_ not modelled 99.8 14 PDB header:transferase Chain: B: PDB Molecule:serine/threonine-protein kinase 4; PDBTitle: crystal structure of mst1 kinase 46 c3hztA_ not modelled 99.8 16 PDB header:transferase Chain: A: PDB Molecule:calcium-dependent protein kinase 3; PDBTitle: crystal structure of toxoplasma gondii cdpk3, tgme49_105860 47 c2a27B_ not modelled 99.8 16 PDB header:transferase Chain: B: PDB Molecule:death-associated protein kinase 2; PDBTitle: human drp-1 kinase, w305s s308a d40 mutant, crystal form with 82 monomers in the asymmetric unit 48 c2wtkB_ not modelled 99.8 13 PDB header:transferase/metal-binding protein Chain: B: PDB Molecule:ste20-related kinase adapter protein alpha; PDBTitle: structure of the heterotrimeric lkb1-stradalpha-mo25alpha2 complex 49 c2bmcD_ not modelled 99.8 16 PDB header:transferase Chain: D: PDB Molecule:serine threonine-protein kinase 6; PDBTitle: aurora-2 t287d t288d complexed with pha-680632 50 c3dzoA_ not modelled 99.8 10 PDB header:transferase Chain: A: PDB Molecule:rhoptry kinase domain; PDBTitle: crystal structure of a rhoptry kinase from toxoplasma gondii 51 c3g0eA_ not modelled 99.8 13 PDB header:transferase Chain: A: PDB Molecule:mast/stem cell growth factor receptor; PDBTitle: kit kinase domain in complex with sunitinib 52 d1qpca_ not modelled 99.8 16 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 53 c3dfaA_ not modelled 99.8 18 PDB header:transferase Chain: A: PDB Molecule:calcium-dependent protein kinase cgd3_920; PDBTitle: crystal structure of kinase domain of calcium-dependent protein kinase2 cgd3_920 from cryptosporidium parvum 54 c2exeA_ not modelled 99.7 14 PDB header:transferase Chain: A: PDB Molecule:dual specificity protein kinase clk3; PDBTitle: crystal structure of the phosphorylated clk3 55 c2qg5D_ not modelled 99.7 13 PDB header:transferase Chain: D: PDB Molecule:calcium/calmodulin-dependent protein kinase; PDBTitle: cryptosporidium parvum calcium dependent protein kinase cgd7_1840 56 d2jfla1 not modelled 99.7 12 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 57 c3zzwA_ not modelled 99.7 12 PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase transmembrane receptor ror2; PDBTitle: crystal structure of the kinase domain of ror2 58 c2vd5A_ not modelled 99.7 14 PDB header:transferase Chain: A: PDB Molecule:dmpk protein; PDBTitle: structure of human myotonic dystrophy protein kinase in2 complex with the bisindoylmaleide inhibitor bim viii 59 c1lufA_ not modelled 99.7 13 PDB header:transferase Chain: A: PDB Molecule:muscle-specific tyrosine kinase receptor musk; PDBTitle: crystal structure of the musk tyrosine kinase: insights2 into receptor autoregulation 60 d1lufa_ not modelled 99.7 13 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 61 d1jksa_ not modelled 99.7 15 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 62 c2j51A_ not modelled 99.7 12 PDB header:transferase Chain: A: PDB Molecule:ste20-like serine/threonine-protein kinase; PDBTitle: crystal structure of human ste20-like kinase bound to 5-2 amino-3-((4-(aminosulfonyl)phenyl)amino)-n-(2,6-3 difluorophenyl)-1h-1,2,4-triazole-1-carbothioamide 63 c1zp9A_ not modelled 99.7 13 PDB header:transferase Chain: A: PDB Molecule:rio1 kinase; PDBTitle: crystal structure of full-legnth a.fulgidus rio1 serine kinase bound2 to atp and mn2+ ions. 64 c2clqA_ not modelled 99.7 13 PDB header:transferase Chain: A: PDB Molecule:mitogen-activated protein kinase kinase kinase 5; PDBTitle: structure of mitogen-activated protein kinase kinase kinase2 5 65 c2qhnA_ not modelled 99.7 15 PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase chk1; PDBTitle: crystal structure of chek1 in complex with inhibitor 1a 66 c2onlD_ not modelled 99.7 14 PDB header:transferase Chain: D: PDB Molecule:map kinase-activated protein kinase 2; PDBTitle: crystal structure of the p38a-mapkap kinase 2 heterodimer 67 c3plsA_ not modelled 99.7 17 PDB header:transferase Chain: A: PDB Molecule:macrophage-stimulating protein receptor; PDBTitle: ron in complex with ligand amp-pnp 68 c3kvwA_ not modelled 99.7 17 PDB header:transferase Chain: A: PDB Molecule:dual specificity tyrosine-phosphorylation-regulated kinase PDBTitle: crystal structure of dual-specificity tyrosine phosphorylation2 regulated kinase 2 (dyrk2) in complex with an indirubin ligand 69 c2cgvA_ not modelled 99.7 13 PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase chk1; PDBTitle: identification of chemically diverse chk1 inhibitors by2 receptor-based virtual screening 70 c1mruB_ not modelled 99.7 19 PDB header:transferase Chain: B: PDB Molecule:probable serine/threonine-protein kinase pknb; PDBTitle: intracellular ser/thr protein kinase domain of2 mycobacterium tuberculosis pknb. 71 d1o6ya_ not modelled 99.7 18 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 72 c3lxkA_ not modelled 99.7 17 PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase jak3; PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6 73 c2ya9A_ not modelled 99.7 16 PDB header:transferase Chain: A: PDB Molecule:death-associated protein kinase 2; PDBTitle: crystal structure of the autoinhibited form of mouse dapk2 74 d1u59a_ not modelled 99.7 11 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 75 c2ivsA_ not modelled 99.7 13 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase receptor PDBTitle: crystal structure of non-phosphorylated ret tyrosine kinase2 domain 76 c2wqmA_ not modelled 99.7 17 PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase nek7; PDBTitle: structure of apo human nek7 77 d1nvra_ not modelled 99.7 13 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 78 d1o6la_ not modelled 99.7 13 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 79 c3i6wB_ not modelled 99.7 15 PDB header:transferase Chain: B: PDB Molecule:serine/threonine-protein kinase chk2; PDBTitle: structure and activation mechanism of the chk2 dna-damage checkpoint2 kinase 80 c2pvfA_ not modelled 99.7 11 PDB header:transferase Chain: A: PDB Molecule:fibroblast growth factor receptor 2; PDBTitle: crystal structure of tyrosine phosphorylated activated fgf2 receptor 2 (fgfr2) kinase domain in complex with atp3 analog and substrate peptide 81 d1xjda_ not modelled 99.7 14 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 82 c1xjdA_ not modelled 99.7 14 PDB header:transferase Chain: A: PDB Molecule:protein kinase c, theta type; PDBTitle: crystal structure of pkc-theta complexed with staurosporine2 at 2a resolution 83 d2psqa1 not modelled 99.7 12 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 84 c2psqA_ not modelled 99.7 12 PDB header:transferase Chain: A: PDB Molecule:fibroblast growth factor receptor 2; PDBTitle: crystal structure of unphosphorylated unactivated wild type2 fgf receptor 2 (fgfr2) kinase domain 85 d1ckia_ not modelled 99.7 13 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 86 c2chlA_ not modelled 99.7 17 PDB header:transferase Chain: A: PDB Molecule:casein kinase i isoform gamma-3; PDBTitle: structure of casein kinase 1 gamma 3 87 c1tqmA_ not modelled 99.7 19 PDB header:ribosome Chain: A: PDB Molecule:conserved hypothetical protein; PDBTitle: crystal structure of a. fulgidus rio2 serine protein kinase bound to2 amppnp 88 d1xwsa_ not modelled 99.7 14 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 89 c2r7bA_ not modelled 99.6 15 PDB header:signaling protein, transferase Chain: A: PDB Molecule:phosphoinositide-dependent protein kinase 1; PDBTitle: crystal structure of the phosphoinositide-dependent kinase-2 1 (pdk-1)catalytic domain bound to a dibenzonaphthyridine3 inhibitor 90 c3cblA_ not modelled 99.6 11 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps; PDBTitle: crystal structure of human feline sarcoma viral oncogene homologue (v-2 fes) in complex with staurosporine and a consensus peptide 91 c2x4fA_ not modelled 99.6 14 PDB header:transferase Chain: A: PDB Molecule:myosin light chain kinase family member 4; PDBTitle: the crystal structure of the human myosin light chain2 kinase loc340156. 92 c2bdwB_ not modelled 99.6 14 PDB header:transferase Chain: B: PDB Molecule:hypothetical protein k11e8.1d; PDBTitle: crystal structure of the auto-inhibited kinase domain of2 calcium/calmodulin activated kinase ii 93 c1zrzA_ not modelled 99.6 14 PDB header:transferase Chain: A: PDB Molecule:protein kinase c, iota; PDBTitle: crystal structure of the catalytic domain of atypical2 protein kinase c-iota 94 d1k2pa_ not modelled 99.6 14 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 95 c2vz6A_ not modelled 99.6 14 PDB header:transferase Chain: A: PDB Molecule:calcium calmodulin dependent protein kinase type ii alpha PDBTitle: structure of human calcium calmodulin dependent protein2 kinase type ii alpha (camk2a) in complex with indirubin3 e804 96 c2y94A_ not modelled 99.6 15 PDB header:transferase Chain: A: PDB Molecule:5'-amp-activated protein kinase catalytic subunit alpha-1; PDBTitle: structure of an active form of mammalian ampk 97 c3is5E_ not modelled 99.6 18 PDB header:transferase Chain: E: PDB Molecule:calcium-dependent protein kinase; PDBTitle: crystal structure of cdpk kinase domain from toxoplasma gondii,2 tgme49_018720 98 c3sxrA_ not modelled 99.6 13 PDB header:transferase/transferase inhibitor Chain: A: PDB Molecule:cytoplasmic tyrosine-protein kinase bmx; PDBTitle: crystal structure of bmx non-receptor tyrosine kinase complex with2 dasatinib 99 d1uu3a_ not modelled 99.6 15 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 100 c2j2iB_ not modelled 99.6 14 PDB header:transferase Chain: B: PDB Molecule:proto-oncogene serine/threonine-protein kinase pim-1; PDBTitle: crystal structure of the humab pim1 in complex with2 ly333531 101 c3p1aA_ not modelled 99.6 11 PDB header:transferase Chain: A: PDB Molecule:membrane-associated tyrosine- and threonine-specific cdc2- PDBTitle: structure of human membrane-associated tyrosine- and threonine-2 specific cdc2-inhibitory kinase myt1 (pkmyt1) 102 c2qluA_ not modelled 99.6 14 PDB header:transferase Chain: A: PDB Molecule:activin receptor type iib; PDBTitle: crystal structure of activin receptor type ii kinase domain2 from human 103 c3lltA_ not modelled 99.6 15 PDB header:transferase Chain: A: PDB Molecule:serine/threonine kinase-1, pflammer; PDBTitle: crystal structure of pf14_0431, kinase domain. 104 c3lxnA_ not modelled 99.6 15 PDB header:transferase Chain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2; PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6 105 c2wu6A_ not modelled 99.6 12 PDB header:transferase Chain: A: PDB Molecule:dual specificity protein kinase clk3; PDBTitle: crystal structure of the human clk3 in complex with dki 106 c2in6A_ not modelled 99.6 15 PDB header:transferase Chain: A: PDB Molecule:wee1-like protein kinase; PDBTitle: wee1 kinase complex with inhibitor pd311839 107 c3c0hB_ not modelled 99.6 14 PDB header:transferase Chain: B: PDB Molecule:peripheral plasma membrane protein cask; PDBTitle: cask cam-kinase domain- amppnp complex, p1 form 108 c2h6dA_ not modelled 99.6 15 PDB header:signaling protein,transferase Chain: A: PDB Molecule:5'-amp-activated protein kinase catalytic subunit PDBTitle: protein kinase domain of the human 5'-amp-activated protein2 kinase catalytic subunit alpha-2 (ampk alpha-2 chain) 109 d1tkia_ not modelled 99.6 12 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 110 c3dpkA_ not modelled 99.6 13 PDB header:transferase Chain: A: PDB Molecule:macrophage colony-stimulating factor 1 receptor; PDBTitle: cfms tyrosine kinase in complex with a pyridopyrimidinone2 inhibitor 111 d1uwha_ not modelled 99.6 14 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 112 c3cokB_ not modelled 99.6 16 PDB header:transferase Chain: B: PDB Molecule:serine/threonine-protein kinase plk4; PDBTitle: crystal structure of plk4 kinase 113 d1rdqe_ not modelled 99.6 12 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 114 d1iasa_ not modelled 99.6 16 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 115 d1unla_ not modelled 99.6 9 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 116 c2x7fA_ not modelled 99.6 14 PDB header:transferase Chain: A: PDB Molecule:traf2 and nck-interacting protein kinase; PDBTitle: crystal structure of the kinase domain of human traf2- and2 nck-interacting kinase with wee1chk1 inhibitor 117 c3ku2A_ not modelled 99.6 17 PDB header:transferase Chain: A: PDB Molecule:calmodulin-domain protein kinase 1; PDBTitle: crystal structure of inactivated form of cdpk1 from toxoplasma gondii,2 tgme49.101440 118 d1koba_ not modelled 99.6 12 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 119 d1fota_ not modelled 99.6 16 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 120 c2r5tA_ not modelled 99.6 13 PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase sgk1; PDBTitle: crystal structure of inactive serum and glucocorticoid-2 regulated kinase 1 in complex with amp-pnp

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0