BLASTP 2.2.22 [Sep-27-2009]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= batch____
         (261 letters)

Database: uniref50.fasta 
           3,077,464 sequences; 1,040,396,356 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P36566 Protein smtA n=113 Tax=Gammaproteobacteria RepID...   546   e-154
UniRef50_C4X686 S-adenosylmethionine-dependent methyltransferase...   437   e-121
UniRef50_B0TUI9 Methyltransferase type 12 n=65 Tax=Gammaproteoba...   272   7e-72
UniRef50_Q1ZIA5 SmtA protein n=2 Tax=Gammaproteobacteria RepID=Q...   236   4e-61
UniRef50_Q2NUA0 Putative S-adenosylmethionine-dependent methyltr...   236   7e-61
UniRef50_A3QA14 Methyltransferase type 12 n=16 Tax=Gammaproteoba...   206   4e-52
UniRef50_Q2SJW8 SAM-dependent methyltransferase n=1 Tax=Hahella ...   206   5e-52
UniRef50_Q5QZ69 SAM-dependent methyltransferase n=3 Tax=Alteromo...   203   6e-51
UniRef50_B3PES7 SmtA protein n=1 Tax=Cellvibrio japonicus Ueda10...   197   3e-49
UniRef50_Q1YTE5 Possible methyltransferase n=1 Tax=gamma proteob...   192   8e-48
UniRef50_Q31JJ3 SAM-dependent methyltransferase n=3 Tax=Pisciric...   187   3e-46
UniRef50_C5BHU7 SAM-dependent methyltransferase n=1 Tax=Teredini...   178   2e-43
UniRef50_Q15TU3 Methyltransferase type 11 n=1 Tax=Pseudoalteromo...   174   3e-42
UniRef50_Q21JL0 Methyltransferase type 12 n=1 Tax=Saccharophagus...   173   6e-42
UniRef50_Q1QUF1 SmtA protein n=1 Tax=Chromohalobacter salexigens...   173   7e-42
UniRef50_B4RYI5 SAM-dependent methyltransferase n=2 Tax=Alteromo...   172   9e-42
UniRef50_Q1QA01 Methyltransferase type 11 n=4 Tax=Moraxellaceae ...   170   4e-41
UniRef50_A4XQ92 Methyltransferase type 11 n=17 Tax=Pseudomonas R...   169   6e-41
UniRef50_UPI0000E11711 methyltransferase type 11 n=1 Tax=Glaciec...   169   7e-41
UniRef50_A4VI82 Methyltransferase, putative n=5 Tax=Pseudomonada...   167   2e-40
UniRef50_Q1N5H2 SAM-dependent methyltransferase n=1 Tax=Bermanel...   164   2e-39
UniRef50_A5EV89 S-adenosylmethionine-dependent methyltransferase...   138   2e-31
UniRef50_A4BJS3 Putative SmtA protein n=1 Tax=Reinekea blandensi...   106   8e-22
UniRef50_A3TKD6 Putative methyltransferase n=1 Tax=Janibacter sp...    99   1e-19
UniRef50_B5L6J9 Methyltransferase n=1 Tax=Micromonospora chalcea...    97   7e-19
UniRef50_D1VJQ5 Methyltransferase type 12 n=1 Tax=Frankia sp. Eu...    96   2e-18
UniRef50_A3TLQ5 S-adenosylmethionine-dependent methyltransferase...    94   4e-18
UniRef50_D1V817 Methyltransferase type 12 n=2 Tax=Frankia RepID=...    94   7e-18
UniRef50_C7QBJ1 Methyltransferase type 12 n=15 Tax=Actinomycetal...    93   9e-18
UniRef50_B4V3L4 Methyltransferase n=17 Tax=Streptomyces RepID=B4...    92   2e-17
UniRef50_Q2JD64 Methyltransferase type 11 n=2 Tax=Frankia RepID=...    89   1e-16
UniRef50_B3TMR6 SAM-dependent methyltransferase n=1 Tax=Actinoma...    87   7e-16
UniRef50_A6WCY9 Methyltransferase type 12 n=2 Tax=Actinomycetale...    86   2e-15
UniRef50_C0ZNJ7 Putative methyltransferase n=1 Tax=Rhodococcus e...    86   2e-15
UniRef50_D2SA73 Methyltransferase type 11 n=1 Tax=Geodermatophil...    80   9e-14
UniRef50_A8M0L9 Methyltransferase type 12 n=1 Tax=Salinispora ar...    79   1e-13
UniRef50_A6WDP8 Methyltransferase type 12 n=1 Tax=Kineococcus ra...    74   4e-12
UniRef50_B1BEI5 Probable S-adenosylmethionine-dependent methltra...    72   2e-11
UniRef50_UPI0001B4EB31 methyltransferase n=1 Tax=Streptomyces sp...    72   2e-11
UniRef50_C9NJ50 Methyltransferase type 12 n=8 Tax=Streptomyces R...    72   3e-11
UniRef50_C8XH01 Methyltransferase type 11 n=1 Tax=Nakamurella mu...    71   3e-11
UniRef50_A4FIW0 Methyltransferase n=3 Tax=Actinomycetales RepID=...    70   8e-11
UniRef50_Q8TJW5 Putative uncharacterized protein n=1 Tax=Methano...    68   3e-10
UniRef50_Q47QY4 Putative methyltransferase n=1 Tax=Thermobifida ...    67   5e-10
UniRef50_A3XJF1 Putative uncharacterized protein n=1 Tax=Leeuwen...    66   1e-09
UniRef50_Q46F96 Ubiquinone/menaquinone biosynthesis methyltransf...    64   5e-09
UniRef50_C2HDY5 S-adenosylmethionine-dependent methyltransferase...    63   8e-09
UniRef50_C5CH90 Methyltransferase type 11 n=1 Tax=Kosmotoga olea...    62   1e-08
UniRef50_B0SGJ1 Methylase/methyltransferase n=2 Tax=Leptospira b...    62   1e-08
UniRef50_D1JD52 Putative uncharacterized protein n=1 Tax=uncultu...    62   2e-08
UniRef50_Q3MEY9 Cyclopropane-fatty-acyl-phospholipid synthase n=...    62   2e-08
UniRef50_C9R8S5 Methyltransferase type 11 n=1 Tax=Ammonifex dege...    62   2e-08
UniRef50_A4X9U1 Methyltransferase type 11 n=5 Tax=Actinomycetale...    62   3e-08
UniRef50_D0RTX5 S-adenosylmethionine-dependent methyltransferase...    61   4e-08
UniRef50_Q482G8 3-demethylubiquinone-9 3-methyltransferase n=27 ...    60   6e-08
UniRef50_B5WCF5 Methyltransferase type 11 n=1 Tax=Burkholderia s...    60   6e-08
UniRef50_D0MGM2 Methyltransferase type 11 n=3 Tax=root RepID=D0M...    60   7e-08
UniRef50_Q1QEI9 3-demethylubiquinone-9 3-methyltransferase n=59 ...    60   7e-08
UniRef50_Q8TYX8 SAM-dependent methyltransferase n=1 Tax=Methanop...    60   8e-08
UniRef50_C9LQ45 SmtA protein n=2 Tax=Clostridiales RepID=C9LQ45_...    60   8e-08
UniRef50_A4FIY5 Ubiquinone/menaquinone biosynthesis methyltransf...    60   1e-07
UniRef50_UPI0001AF209D methyltransferase type 11 n=1 Tax=Strepto...    59   1e-07
UniRef50_D1CAG8 Methyltransferase type 11 n=1 Tax=Sphaerobacter ...    59   2e-07
UniRef50_A7NNU9 MCP methyltransferase, CheR-type n=1 Tax=Roseifl...    59   2e-07
UniRef50_Q65GZ7 Putative uncharacterized protein n=1 Tax=Bacillu...    58   3e-07
UniRef50_D1Z1A4 Putative uncharacterized protein n=1 Tax=Methano...    58   3e-07
UniRef50_B0U3W1 3-demethylubiquinone-9 3-methyltransferase n=7 T...    58   4e-07
UniRef50_D2M284 Methyltransferase type 11 n=1 Tax=Bacillus cellu...    58   4e-07
UniRef50_B9K8U5 Ubiquinone/menaquinone biosynthesis methyltransf...    58   4e-07
UniRef50_C7I3S4 Methyltransferase type 11 n=1 Tax=Thiomonas inte...    57   4e-07
UniRef50_Q8TIA7 Phosphatidylethanolamine N-methyltransferase n=3...    57   4e-07
UniRef50_D1JD78 Putative uncharacterized protein n=1 Tax=uncultu...    57   4e-07
UniRef50_C7MUF7 Methylase involved in ubiquinone/menaquinone bio...    57   5e-07
UniRef50_C1RH88 Methylase involved in ubiquinone/menaquinone bio...    57   5e-07
UniRef50_D1C6B8 Methyltransferase type 11 n=2 Tax=Thermomicrobia...    57   5e-07
UniRef50_A8FSR8 Methylase involved in ubiquinone/menaquinone bio...    57   6e-07
UniRef50_B9XNM3 Methyltransferase type 11 n=2 Tax=Verrucomicrobi...    57   6e-07
UniRef50_Q02BK2 Methyltransferase type 12 n=1 Tax=Candidatus Sol...    57   8e-07
UniRef50_C1D1R7 Putative Trans-aconitate 2-methyltransferase n=1...    57   8e-07
UniRef50_Q2FPU4 UbiE/COQ5 methyltransferase n=1 Tax=Methanospiri...    56   9e-07
UniRef50_B0TYT6 S-adenosylmethionine (SAM)-dependent methyltrans...    56   1e-06
UniRef50_Q123Z0 Methyltransferase type 12 n=2 Tax=Polaromonas Re...    56   1e-06
UniRef50_A3CRX6 Glycosyl transferase, family 2 n=1 Tax=Methanocu...    56   1e-06
UniRef50_C5RP33 Methyltransferase type 11 n=1 Tax=Clostridium ce...    56   1e-06
UniRef50_Q01S22 Methyltransferase type 11 n=1 Tax=Candidatus Sol...    56   1e-06
UniRef50_A9KJQ3 Methyltransferase type 11 n=1 Tax=Clostridium ph...    56   2e-06
UniRef50_Q2SLT2 SAM-dependent methyltransferase n=1 Tax=Hahella ...    55   2e-06
UniRef50_A5EL18 Putative methyltransferase n=1 Tax=Bradyrhizobiu...    55   2e-06
UniRef50_A8M9S1 Methyltransferase type 11 n=1 Tax=Caldivirga maq...    55   2e-06
UniRef50_Q73R34 Methlytransferase, UbiE/COQ5 family n=1 Tax=Trep...    55   2e-06
UniRef50_B9XT55 Methyltransferase type 11 n=1 Tax=bacterium Elli...    55   2e-06
UniRef50_A4FLY1 Methyltransferase n=1 Tax=Saccharopolyspora eryt...    55   2e-06
UniRef50_D1A8N4 Methyltransferase type 11 n=2 Tax=Streptosporang...    55   3e-06
UniRef50_A9G9E0 Putative uncharacterized protein n=1 Tax=Sorangi...    55   3e-06
UniRef50_A6C296 UbiE/COQ5 methyltransferase n=2 Tax=Planctomycet...    55   3e-06
UniRef50_B3PI89 Biotin biosynthesis protein BioC n=2 Tax=Pseudom...    55   3e-06
UniRef50_Q2FPT3 UbiE/COQ5 methyltransferase n=1 Tax=Methanospiri...    55   3e-06
UniRef50_A3TVS9 Methyltransferase, UbiE/COQ5 family protein n=1 ...    55   3e-06
UniRef50_Q2FMN6 UbiE/COQ5 methyltransferase n=1 Tax=Methanospiri...    54   4e-06
UniRef50_Q467Y8 Methyltransferase n=2 Tax=Methanosarcina RepID=Q...    54   4e-06
UniRef50_C6D045 Methyltransferase type 11 n=24 Tax=Bacillales Re...    54   4e-06
UniRef50_B3PGF3 Transcriptional regulator, ArsR family n=1 Tax=C...    54   4e-06
UniRef50_C1ZJC9 Methylase involved in ubiquinone/menaquinone bio...    54   4e-06
UniRef50_Q46ER7 UbiE/COQ5 methyltransferase n=4 Tax=Methanosarci...    54   4e-06
UniRef50_D1JEE5 Putative uncharacterized protein n=1 Tax=uncultu...    54   4e-06
UniRef50_A6GID5 Putative uncharacterized protein n=1 Tax=Plesioc...    54   4e-06
UniRef50_C6PBK3 Methyltransferase type 11 n=1 Tax=Thermoanaeroba...    54   4e-06
UniRef50_C5E313 KLTH0H09460p n=1 Tax=Lachancea thermotolerans CB...    54   4e-06
UniRef50_A0RF06 Ubiquinone/menaquinone biosynthesis methyltransf...    54   5e-06
UniRef50_C6A0V9 Cyclopropane-fatty-acyl-phospholipid synthase su...    54   5e-06
UniRef50_Q8TJ84 UbiE/COQ5 methyltransferase n=1 Tax=Methanosarci...    54   5e-06
UniRef50_D1CH64 Methyltransferase type 11 n=1 Tax=Thermobaculum ...    54   5e-06
UniRef50_B1KQ47 Ubiquinone biosynthesis O-methyltransferase n=3 ...    54   6e-06
UniRef50_C9L9K2 SmtA protein n=6 Tax=Bacteria RepID=C9L9K2_RUMHA       54   6e-06
UniRef50_D1JD56 Putative uncharacterized protein n=1 Tax=uncultu...    54   6e-06
UniRef50_C8SD34 Methyltransferase type 11 n=1 Tax=Ferroglobus pl...    54   6e-06
UniRef50_B0BXU1 Methyltransferase n=14 Tax=Rickettsia RepID=B0BX...    54   6e-06
UniRef50_Q8TIG9 Putative uncharacterized protein n=1 Tax=Methano...    54   7e-06
UniRef50_Q28QS3 Methyltransferase type 11 n=1 Tax=Jannaschia sp....    54   7e-06
UniRef50_D2QHG7 Methyltransferase type 11 n=1 Tax=Spirosoma ling...    54   7e-06
UniRef50_C6IWT0 Putative uncharacterized protein n=1 Tax=Paeniba...    54   7e-06
UniRef50_Q0UJE1 Putative uncharacterized protein n=1 Tax=Phaeosp...    53   8e-06
UniRef50_A9B3A0 Methyltransferase type 11 n=1 Tax=Herpetosiphon ...    53   8e-06
UniRef50_A5EVK0 Ubiquinone biosynthesis O-methyltransferase n=2 ...    53   8e-06
UniRef50_C6C7H1 Methyltransferase type 11 n=3 Tax=Enterobacteria...    53   8e-06
UniRef50_B5IUZ3 Methyltransferase, UbiE/COQ5 family n=4 Tax=Ther...    53   9e-06
UniRef50_B1I4Q7 Methyltransferase type 11 n=1 Tax=Candidatus Des...    53   9e-06
UniRef50_Q2B0R2 Methyltransferase n=1 Tax=Bacillus sp. NRRL B-14...    53   9e-06
UniRef50_A8TN55 Methyltransferase n=3 Tax=Alphaproteobacteria Re...    53   1e-05
UniRef50_A9UU62 Predicted protein n=1 Tax=Monosiga brevicollis R...    53   1e-05
UniRef50_A9GTB2 Methyltransferase n=1 Tax=Sorangium cellulosum '...    53   1e-05
UniRef50_A0QIL0 Thiopurine S-methyltransferase (Tpmt) superfamil...    53   1e-05
UniRef50_A8MFN6 Methyltransferase type 11 n=1 Tax=Alkaliphilus o...    52   1e-05
UniRef50_A1AM59 Methyltransferase type 11 n=2 Tax=Pelobacter Rep...    52   1e-05
UniRef50_A5MZZ8 Predicted methyltransferase n=2 Tax=Clostridium ...    52   1e-05
UniRef50_B1L3G9 Methyltransferase type 11 n=1 Tax=Candidatus Kor...    52   1e-05
UniRef50_B6R6V6 Methyltransferase, UbiE/COQ5 family n=1 Tax=Pseu...    52   1e-05
UniRef50_A4X1E6 Methyltransferase type 11 n=5 Tax=Actinobacteria...    52   1e-05
UniRef50_B8FRY0 Methyltransferase type 12 n=2 Tax=Desulfitobacte...    52   2e-05
UniRef50_A8MFN7 Methyltransferase type 11 n=1 Tax=Alkaliphilus o...    52   2e-05
UniRef50_Q7U920 Putative uncharacterized protein n=1 Tax=Synecho...    52   2e-05
UniRef50_C0ZCL2 Putative uncharacterized protein n=1 Tax=Breviba...    52   2e-05
UniRef50_Q97TL7 SAM-dependent methyltransferase n=2 Tax=Clostrid...    52   2e-05
UniRef50_B3QX57 Methyltransferase type 11 n=1 Tax=Chloroherpeton...    52   2e-05
UniRef50_A7I8W9 Methyltransferase type 11 n=3 Tax=Methanomicrobi...    52   2e-05
UniRef50_C5A2C6 SAM-dependent methyltransferase, ubiE/COQ5 famil...    52   2e-05
UniRef50_Q01YM7 Methyltransferase type 11 n=1 Tax=Candidatus Sol...    52   2e-05
UniRef50_C5FG45 Crg1p n=1 Tax=Microsporum canis CBS 113480 RepID...    52   2e-05
UniRef50_D1XAK7 Methyltransferase type 11 n=1 Tax=Streptomyces s...    52   2e-05
UniRef50_A7H6R5 Methyltransferase type 12 n=3 Tax=Anaeromyxobact...    52   2e-05
UniRef50_Q3AS64 Methyltransferase, putative n=1 Tax=Chlorobium c...    52   2e-05
UniRef50_A5INN1 Methyltransferase type 12 n=12 Tax=Thermotogacea...    52   2e-05
UniRef50_A7MPA9 3-demethylubiquinone-9 3-methyltransferase n=6 T...    52   3e-05
UniRef50_B2A8G5 Methyltransferase type 11 n=1 Tax=Natranaerobius...    52   3e-05
UniRef50_B0NQC1 Putative uncharacterized protein n=1 Tax=Bactero...    52   3e-05
UniRef50_Q0BV11 Methyltransferase n=1 Tax=Granulibacter bethesde...    52   3e-05
UniRef50_B8H209 3-demethylubiquinone-9 3-methyltransferase n=13 ...    51   3e-05
UniRef50_C9CSA7 Methyltransferase, UbiE/COQ5 family n=1 Tax=Sili...    51   3e-05
UniRef50_A1D5R5 Putative uncharacterized protein n=1 Tax=Neosart...    51   3e-05
UniRef50_B3ENM4 Magnesium protoporphyrin O-methyltransferase n=7...    51   3e-05
UniRef50_A7NQ08 Methyltransferase type 11 n=5 Tax=Chloroflexacea...    51   4e-05
UniRef50_Q012C7 Dihydroxypolyprenylbenzoate methyltransferase (I...    51   4e-05
UniRef50_C8W6C7 Methyltransferase type 11 n=1 Tax=Desulfotomacul...    51   4e-05
UniRef50_A2CBD3 SAM (And some other nucleotide) binding motif:TP...    51   4e-05
UniRef50_B4B3H0 Methyltransferase type 11 n=1 Tax=Cyanothece sp....    51   4e-05
UniRef50_UPI00016BFDE3 SAM-dependent methyltransferase n=1 Tax=E...    51   4e-05
UniRef50_Q1AZ81 Demethylmenaquinone methyltransferase n=1 Tax=Ru...    51   4e-05
UniRef50_A4Z3A6 Putative uncharacterized protein n=1 Tax=Bradyrh...    51   4e-05
UniRef50_Q6MHC4 3-demethylubiquinone-9 3-methyltransferase n=1 T...    51   4e-05
UniRef50_Q5WCE8 S-adenosylmethionine (SAM)-dependent methyltrans...    51   5e-05
UniRef50_D1BJP6 Methylase involved in ubiquinone/menaquinone bio...    51   5e-05
UniRef50_D0NEB7 Trans-aconitate 2-methyltransferase, putative n=...    50   5e-05
UniRef50_C0VYW5 Possible ubiquinone/menaquinone biosynthesis met...    50   5e-05
UniRef50_A8KYQ0 Methyltransferase type 12 n=2 Tax=Frankia RepID=...    50   5e-05
UniRef50_D2PTC3 Methyltransferase type 11 n=1 Tax=Kribbella flav...    50   6e-05
UniRef50_UPI0000E48A5D PREDICTED: hypothetical protein n=4 Tax=S...    50   6e-05
UniRef50_D2RYJ5 Methyltransferase type 11 n=3 Tax=Haloterrigena ...    50   6e-05
UniRef50_B0A8V1 Putative uncharacterized protein n=1 Tax=Clostri...    50   6e-05
UniRef50_C6DDT8 Biotin biosynthesis protein BioC n=6 Tax=Enterob...    50   6e-05
UniRef50_B4RIP1 Tetratricopeptide repeat/protein kinase domain p...    50   6e-05
UniRef50_D1NAT1 Trans-aconitate 2-methyltransferase n=1 Tax=Vict...    50   6e-05
UniRef50_B3E3C6 Methyltransferase type 12 n=1 Tax=Geobacter lovl...    50   7e-05
UniRef50_Q21DX2 Methyltransferase type 11 n=2 Tax=Gammaproteobac...    50   7e-05
UniRef50_C0CIH7 Putative uncharacterized protein n=1 Tax=Blautia...    50   7e-05
UniRef50_A9FQ40 3-demethylubiquinone-9 3-O-methyltransferase n=1...    50   7e-05
UniRef50_C4NCJ8 SAM-dependent methyltransferase n=1 Tax=Streptom...    50   7e-05
UniRef50_Q21UL3 3-demethylubiquinone-9 3-methyltransferase n=5 T...    50   7e-05
UniRef50_UPI0001B57FBF MCP methyltransferase, CheR-type n=1 Tax=...    50   7e-05
UniRef50_C9N8D9 Methyltransferase type 11 n=6 Tax=Streptomyces R...    50   8e-05
UniRef50_Q09E54 Putative uncharacterized protein n=1 Tax=Stigmat...    50   8e-05
UniRef50_Q0RJM9 Putative methyltransferase n=1 Tax=Frankia alni ...    50   8e-05
UniRef50_Q033A8 SAM-dependent methyltransferase n=6 Tax=Firmicut...    50   8e-05
UniRef50_B3QY97 Methyltransferase type 11 n=1 Tax=Chloroherpeton...    50   8e-05
UniRef50_B5JEA6 Methyltransferase domain family n=1 Tax=Verrucom...    50   8e-05
UniRef50_B2WBS7 Methyltransferase UbiE n=2 Tax=Pleosporineae Rep...    50   9e-05
UniRef50_B3QZ54 Magnesium protoporphyrin O-methyltransferase n=6...    50   9e-05
UniRef50_C7JGN3 Biotin synthesis protein n=8 Tax=Acetobacter pas...    50   9e-05
UniRef50_C0ZBF0 Putative uncharacterized protein n=1 Tax=Breviba...    50   9e-05
UniRef50_C5FIU1 Cyclopropane-fatty-acyl-phospholipid synthase n=...    50   9e-05
UniRef50_UPI0001788486 Methyltransferase type 11 n=1 Tax=Geobaci...    50   1e-04
UniRef50_A6CF73 Methyltransferase type 11 n=1 Tax=Planctomyces m...    50   1e-04
UniRef50_A5ZYR5 Putative uncharacterized protein (Fragment) n=1 ...    50   1e-04
UniRef50_A4EUG7 Methyltransferase, UbiE/COQ5 family protein n=5 ...    50   1e-04
UniRef50_C5UZZ2 Methyltransferase type 11 n=1 Tax=Gallionella fe...    50   1e-04
UniRef50_A8TQ26 Tetratricopeptide TPR_4 n=1 Tax=alpha proteobact...    50   1e-04
UniRef50_O18235 Protein Y57G11C.11a, confirmed by transcript evi...    50   1e-04
UniRef50_P08442 Uncharacterized protein syc1184_c n=29 Tax=Cyano...    50   1e-04
UniRef50_Q0G0C8 SAM (And some other nucleotide) binding motif:Ge...    50   1e-04
UniRef50_Q2RJ99 UbiE/COQ5 methyltransferase n=1 Tax=Moorella the...    50   1e-04
UniRef50_Q9EYI2 SnogM n=1 Tax=Streptomyces nogalater RepID=Q9EYI...    50   1e-04
UniRef50_Q1ITC0 Putative uncharacterized protein n=1 Tax=Candida...    49   1e-04
UniRef50_C5S6C8 Methyltransferase type 11 n=1 Tax=Allochromatium...    49   1e-04
UniRef50_Q8D299 BioC protein n=1 Tax=Wigglesworthia glossinidia ...    49   1e-04
UniRef50_B5YA44 Putative methyl transferase n=2 Tax=Firmicutes R...    49   1e-04
UniRef50_A3UCE4 Methyltransferase, UbiE/COQ5 family protein n=1 ...    49   1e-04
UniRef50_Q0W229 Putative uncharacterized protein n=1 Tax=uncultu...    49   1e-04
UniRef50_A5CQB8 Putative methyltransferase n=2 Tax=Clavibacter m...    49   1e-04
UniRef50_C8VZ57 Methyltransferase type 11 n=1 Tax=Desulfotomacul...    49   1e-04
UniRef50_D2B333 Methyltransferase type 11 n=4 Tax=Actinomycetale...    49   1e-04
UniRef50_Q9RX93 Trans-aconitate 2-methyltransferase n=2 Tax=Dein...    49   1e-04
UniRef50_Q9RYC4 Methyltransferase, putative n=2 Tax=Deinococcus ...    49   1e-04
UniRef50_B4UHL7 Methyltransferase type 11 n=41 Tax=Bacteria RepI...    49   2e-04
UniRef50_B8FTI1 Methyltransferase type 11 n=2 Tax=Desulfitobacte...    49   2e-04
UniRef50_Q465A0 Putative uncharacterized protein n=2 Tax=Methano...    49   2e-04
UniRef50_B5JNH0 Methyltransferase domain family n=1 Tax=Verrucom...    49   2e-04
UniRef50_UPI000186D07C hexaprenyldihydroxybenzoate methyltransfe...    49   2e-04
UniRef50_Q47PB3 S-adenosylmethionine (SAM)-dependent methyltrans...    49   2e-04
UniRef50_B8DK00 Methyltransferase type 11 n=1 Tax=Desulfovibrio ...    49   2e-04
UniRef50_Q0YPN2 Protein-L-isoaspartate(D-aspartate) O-methyltran...    49   2e-04
UniRef50_B6GZM9 Pc12g02220 protein n=13 Tax=Eurotiomycetidae Rep...    49   2e-04
UniRef50_Q46JP9 TPR repeat n=2 Tax=Prochlorococcus marinus RepID...    49   2e-04
UniRef50_C7MVS3 Methylase of polypeptide chain release factors n...    49   2e-04
UniRef50_B6IPG3 Trans-aconitate 2-methyltransferase n=1 Tax=Rhod...    49   2e-04
UniRef50_C7PGL9 Methyltransferase type 11 n=2 Tax=Sphingobacteri...    49   2e-04
UniRef50_Q4C8V0 Similar to Methylase involved in ubiquinone/mena...    49   2e-04
UniRef50_B1MM82 Putative uncharacterized protein n=1 Tax=Mycobac...    49   2e-04
UniRef50_A0KUS1 Putative uncharacterized protein n=1 Tax=Shewane...    49   2e-04
UniRef50_A8M0N7 Methyltransferase type 11 n=2 Tax=Micromonospora...    49   2e-04
UniRef50_Q40JV5 Biotin synthesis protein BioC n=5 Tax=canis grou...    49   2e-04
UniRef50_Q0RED1 Putative uncharacterized protein n=1 Tax=Frankia...    49   2e-04
UniRef50_D2L665 Methyltransferase type 11 n=1 Tax=Desulfovibrio ...    49   2e-04
UniRef50_A8M6Z4 Methyltransferase type 11 n=5 Tax=Actinomycetale...    49   2e-04
UniRef50_C4RH30 SAM-dependent methyltransferase n=2 Tax=Actinomy...    49   2e-04
UniRef50_B5K1D7 Methyltransferase, UbiE/COQ5 family n=3 Tax=Rhod...    49   2e-04
UniRef50_Q9K8W5 BH2887 protein n=1 Tax=Bacillus halodurans RepID...    49   2e-04
UniRef50_B1L4G6 Methyltransferase type 11 n=2 Tax=Archaea RepID=...    49   2e-04
UniRef50_C7QDP7 Methyltransferase type 11 n=3 Tax=Actinomycetale...    48   3e-04
UniRef50_C1PBY7 Methyltransferase type 11 n=1 Tax=Bacillus coagu...    48   3e-04
UniRef50_UPI0001A4295A methyltransferase type 11 n=1 Tax=Pectoba...    48   3e-04
UniRef50_C5BMU9 SAM-dependent methyltransferase n=1 Tax=Teredini...    48   3e-04

>UniRef50_P36566 Protein smtA n=113 Tax=Gammaproteobacteria RepID=SMTA_ECOLI
          Length = 261

 Score =  546 bits (1407), Expect = e-154,   Method: Compositional matrix adjust.
 Identities = 261/261 (100%), Positives = 261/261 (100%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI
Sbjct: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
           KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA
Sbjct: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
           VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL
Sbjct: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180

Query: 181 SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP 240
           SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP
Sbjct: 181 SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP 240

Query: 241 YITLGRYIHVTARKPQSKDKV 261
           YITLGRYIHVTARKPQSKDKV
Sbjct: 241 YITLGRYIHVTARKPQSKDKV 261


>UniRef50_C4X686 S-adenosylmethionine-dependent methyltransferase n=56
           Tax=Enterobacteriaceae RepID=C4X686_KLEPN
          Length = 270

 Score =  437 bits (1125), Expect = e-121,   Method: Compositional matrix adjust.
 Identities = 208/266 (78%), Positives = 231/266 (86%), Gaps = 5/266 (1%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           +QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDL+ +LA++GP  LRVLDAGGGEGQTAI
Sbjct: 5   VQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLEPLLAQLGPGPLRVLDAGGGEGQTAI 64

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
           K+A+ GH V LCDLSA+M+ RA+QAA  KGV DNM F+ CAAQD+A HLE+PVDL+LFHA
Sbjct: 65  KVAQLGHHVTLCDLSAEMVARARQAAADKGVIDNMHFVQCAAQDIAQHLESPVDLVLFHA 124

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
           VLEWVA+P+ +L TLWS LR GG LSLMFYNA+GLLMHNMVAGNFDYVQ GMPKKKKRTL
Sbjct: 125 VLEWVAEPQEILHTLWSTLRAGGGLSLMFYNANGLLMHNMVAGNFDYVQLGMPKKKKRTL 184

Query: 181 SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP 240
           SPDYPR+P QVY WLEE GWQI+ KTGVRVFHDYLREK QQ D Y ALL LETRYCRQEP
Sbjct: 185 SPDYPREPQQVYHWLEEIGWQIVSKTGVRVFHDYLREKRQQHDSYAALLALETRYCRQEP 244

Query: 241 YITLGRYIHVTARKPQS-----KDKV 261
           Y++LGRYIHVTA K Q+     KDKV
Sbjct: 245 YLSLGRYIHVTALKSQAHSRRCKDKV 270


>UniRef50_B0TUI9 Methyltransferase type 12 n=65 Tax=Gammaproteobacteria
           RepID=B0TUI9_SHEHH
          Length = 287

 Score =  272 bits (696), Expect = 7e-72,   Method: Compositional matrix adjust.
 Identities = 124/259 (47%), Positives = 177/259 (68%), Gaps = 6/259 (2%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQ------KLRVLDAGGGE 55
           QDRNFD +A KF+ +IYGT KG++RQ ++WQD++++L  +  Q      +L VLDAGGG 
Sbjct: 27  QDRNFDGLAHKFAASIYGTAKGEIRQTVVWQDIEQILLALSKQPSNAAAELSVLDAGGGL 86

Query: 56  GQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDL 115
            Q + K+A  GH V LCDLS++M+  AKQ      +    QFIH   Q++A HL+ PVDL
Sbjct: 87  AQLSQKIAALGHNVSLCDLSSEMLSLAKQDISDNQLLKKYQFIHSPVQNIAEHLQVPVDL 146

Query: 116 ILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKK 175
           ILFHAV+EW+A+P   L TL   ++PGG++S+MFYN +GLL  N++ GN ++++ GMP +
Sbjct: 147 ILFHAVMEWLAEPIQALSTLCEQVKPGGIISVMFYNYNGLLFKNLICGNLNHIEKGMPHR 206

Query: 176 KKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRY 235
           K+  L P     P  VY  LE+AG+ I+GKTGVR FHDY++        +E ++ +E + 
Sbjct: 207 KRFKLQPQQGIKPELVYSCLEQAGFNILGKTGVRTFHDYMQNHDMGDFSFEQIVAMEQKL 266

Query: 236 CRQEPYITLGRYIHVTARK 254
           CRQEP+++LGRYIHV A+K
Sbjct: 267 CRQEPFLSLGRYIHVYAQK 285


>UniRef50_Q1ZIA5 SmtA protein n=2 Tax=Gammaproteobacteria RepID=Q1ZIA5_9GAMM
          Length = 256

 Score =  236 bits (603), Expect = 4e-61,   Method: Compositional matrix adjust.
 Identities = 118/256 (46%), Positives = 165/256 (64%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M D NFD IA KF +NIYGTTKG++R A++WQ +   LA +  + LR+LDAGGG G  A 
Sbjct: 1   MIDHNFDGIAHKFLKNIYGTTKGKIRTAVVWQAILDCLALLPQRPLRILDAGGGCGFLAQ 60

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
           K+A  GHQV+LCD+S  ++D AK+  + K  + N+  IHC  Q ++ H++   DLIL HA
Sbjct: 61  KLAAMGHQVVLCDISKVLLDEAKKQMQGKDFAKNVHIIHCPIQQLSEHVDADFDLILNHA 120

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
           VLEW+  P+  LQ L ++L   GV+SLMFYN      HN++  NFD+V+ GM +KK   L
Sbjct: 121 VLEWLECPKQTLQGLLTLLNVNGVMSLMFYNKDAQRFHNLLCANFDFVERGMLRKKVVRL 180

Query: 181 SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP 240
           +P +P     V  WL+E  + ++ KTGVR+ HDYL++  Q    Y  LL +E +Y +QEP
Sbjct: 181 TPTHPLLEKDVQSWLKEVNFYVLQKTGVRIIHDYLKDPTQSVHKYAQLLAMEQKYNQQEP 240

Query: 241 YITLGRYIHVTARKPQ 256
           Y +LGRY H+  +  Q
Sbjct: 241 YASLGRYTHLMIKATQ 256


>UniRef50_Q2NUA0 Putative S-adenosylmethionine-dependent methyltransferase n=1
           Tax=Sodalis glossinidius str. 'morsitans'
           RepID=Q2NUA0_SODGM
          Length = 199

 Score =  236 bits (601), Expect = 7e-61,   Method: Compositional matrix adjust.
 Identities = 114/194 (58%), Positives = 143/194 (73%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           +QDRNFDDIA+KF+RNIYGTTKG++RQA+LWQDL  +LA +  + L +LDAGGGEG+ A 
Sbjct: 2   IQDRNFDDIADKFARNIYGTTKGKIRQAVLWQDLQTLLAHLPQRPLCILDAGGGEGRIAA 61

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
           ++A  GH V+LCDLSAQMI RA+Q A+  GV    + +  A QD+ +HLE   DLIL HA
Sbjct: 62  QLATLGHDVVLCDLSAQMIHRAQQQAKTLGVEQRFRCVQSAIQDIGTHLERHADLILCHA 121

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
           VLEWVA P ++LQ L   L   G LSLMFYN HGL++ NM+ GN  +V AGMPK+KKR+L
Sbjct: 122 VLEWVAQPEALLQILNQCLAGDGALSLMFYNKHGLVIRNMLLGNMAFVAAGMPKRKKRSL 181

Query: 181 SPDYPRDPAQVYLW 194
            PD+P DPA    W
Sbjct: 182 MPDHPCDPADWKKW 195


>UniRef50_A3QA14 Methyltransferase type 12 n=16 Tax=Gammaproteobacteria
           RepID=A3QA14_SHELP
          Length = 284

 Score =  206 bits (525), Expect = 4e-52,   Method: Compositional matrix adjust.
 Identities = 103/257 (40%), Positives = 154/257 (59%), Gaps = 4/257 (1%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           +QD+NFD +A KF++NIYGT KG++R A+LW+D+ + + ++    LR+LDAGGG G  + 
Sbjct: 25  VQDKNFDALAGKFAKNIYGTPKGEVRAAVLWRDISQAMTQLPEGPLRILDAGGGFGFFSQ 84

Query: 61  KMAERGHQVILCDLSAQMIDRAK-QAAEAKGVSD---NMQFIHCAAQDVASHLETPVDLI 116
           K+A+ GH V LCD+S++M+   + Q  E +  S    ++  +H   Q +        DLI
Sbjct: 85  KLAKLGHSVTLCDISSEMLALGQAQITEYENNSGEKLDITLLHAPIQSLTREELGQFDLI 144

Query: 117 LFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKK 176
           L HAV EW++D +  L  L  +L+P G+ SLMFYN   +  H++++GNFDYV A    KK
Sbjct: 145 LCHAVAEWLSDAKQTLAGLTQLLKPQGLFSLMFYNKEAMRFHSLISGNFDYVAADFKVKK 204

Query: 177 KRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYC 236
           K  L+P YP     V  W+ +   +++  +GVRV HDYL+        +  LLE+E +Y 
Sbjct: 205 KVGLTPSYPLYIDDVRGWVSDWQMELVTASGVRVIHDYLKTHQPPNSDFSQLLEMELQYS 264

Query: 237 RQEPYITLGRYIHVTAR 253
               YI LGRY+H   R
Sbjct: 265 THPAYIGLGRYVHFITR 281


>UniRef50_Q2SJW8 SAM-dependent methyltransferase n=1 Tax=Hahella chejuensis KCTC
           2396 RepID=Q2SJW8_HAHCH
          Length = 264

 Score =  206 bits (525), Expect = 5e-52,   Method: Compositional matrix adjust.
 Identities = 107/252 (42%), Positives = 161/252 (63%), Gaps = 2/252 (0%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAE-MGPQKLRVLDAGGGEGQTAIKMA 63
           NFD++ E+F  NIYGT KG+LR  ++ +DLD  LAE +G    R+LD G G    + ++A
Sbjct: 12  NFDELKERFQNNIYGTPKGRLRLDLINEDLDAHLAERLGEGAWRILDIGCGAAMISGRLA 71

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVS-DNMQFIHCAAQDVASHLETPVDLILFHAVL 122
           + GH++ L DLSA+M+  A+   E+ G +    ++     QDV   L+ P DLI+ HAVL
Sbjct: 72  QAGHRLTLTDLSAEMLTAARANLESLGSALACEEWREGPMQDVLPQLQGPYDLIIIHAVL 131

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSP 182
           EW+ DPR  L+   S LRPGGVLSL FYN +GL+  N++ GNF  ++      +K  L+P
Sbjct: 132 EWMDDPRPALELALSKLRPGGVLSLAFYNRNGLIYRNLLQGNFRKLKKNNWYYRKGGLTP 191

Query: 183 DYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPYI 242
             P DP +VY WL +A  +++ K G+R F+D++++   +   YE +LE+E  + ++EPY+
Sbjct: 192 QNPLDPDEVYNWLAQADMRLICKRGIRTFYDFMQKPVARERSYEDVLEMERMHSQKEPYL 251

Query: 243 TLGRYIHVTARK 254
           +LGRYIHV  +K
Sbjct: 252 SLGRYIHVLYQK 263


>UniRef50_Q5QZ69 SAM-dependent methyltransferase n=3 Tax=Alteromonadales
           RepID=Q5QZ69_IDILO
          Length = 262

 Score =  203 bits (516), Expect = 6e-51,   Method: Compositional matrix adjust.
 Identities = 111/258 (43%), Positives = 156/258 (60%), Gaps = 7/258 (2%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
           +F  I++KFS++IY TTKGQLR  +L +DL  +LA    +   VLD G G GQ      E
Sbjct: 10  DFSGISQKFSKSIYDTTKGQLRVEVLKRDLAPLLA---TEPCLVLDVGAGLGQVNQWFQE 66

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLE-TPVDLILFHAVLE 123
           +G  V+  DLS +MI+ A++  +A G+    +++  +  ++ +    +  D+IL HAVLE
Sbjct: 67  KGFTVVHSDLSTEMIEEAERRHKAAGLGHKCKYVAASLTELVNQQPLSQYDIILCHAVLE 126

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPD 183
           W+ D    +  L S+L+PGG LSLMFYN H  L  N + GNFDY++ G+  KK   LSP+
Sbjct: 127 WLPDTELAIHQLASLLKPGGKLSLMFYNYHAKLFANAIYGNFDYIERGLKVKKTVRLSPE 186

Query: 184 YPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLRE-KHQQRDCYEALLELETRYCRQEPYI 242
            P  P QV  WLE+ G  +  KTGVR FHDYLR+  HQQR  ++ LL LE +Y +  PY 
Sbjct: 187 NPAVPEQVGCWLEQEGLNVQQKTGVRCFHDYLRDLTHQQR--FDELLALEMKYNQMSPYR 244

Query: 243 TLGRYIHVTARKPQSKDK 260
            LGRY H    KP  +++
Sbjct: 245 ELGRYQHWLIEKPNCQEE 262


>UniRef50_B3PES7 SmtA protein n=1 Tax=Cellvibrio japonicus Ueda107
           RepID=B3PES7_CELJU
          Length = 281

 Score =  197 bits (501), Expect = 3e-49,   Method: Compositional matrix adjust.
 Identities = 100/255 (39%), Positives = 160/255 (62%), Gaps = 7/255 (2%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGP-----QKLRVLDAGGGEG 56
           QDRNFDD+A++F +NIYG  KG +R A+L +D    L  + P      + R+LDAGGG+G
Sbjct: 8   QDRNFDDLAKRFRKNIYGGLKGDVRLAVLERDCLACLP-IAPFQQPGNRWRILDAGGGQG 66

Query: 57  QTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETP-VDL 115
           Q ++++A  GH+V+LCD+SA+M+  A+       + D +  +H A QD+   ++    D 
Sbjct: 67  QFSLQLAAAGHEVVLCDISAEMLKLAEAHITHCQLQDRVTLVHAAIQDLPRVIDDHRFDF 126

Query: 116 ILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKK 175
           ++ HAV+EW+ DP+S+L  L + L+P G LSL FYN H L+  N++  NF  +++     
Sbjct: 127 VICHAVMEWMQDPQSLLPCLLNYLKPEGYLSLTFYNLHSLIYKNLLRTNFKKIRSRDYAG 186

Query: 176 KKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRY 235
           +K +L+P  P  P QV  W+ E   Q++  +G+RVFHDY+ ++ ++      L+E+E  +
Sbjct: 187 QKGSLTPINPLMPEQVLQWVGELPLQLLSHSGIRVFHDYIFDEEKRERDPAGLVEMELLF 246

Query: 236 CRQEPYITLGRYIHV 250
            +QEPY +LGRY H+
Sbjct: 247 SQQEPYRSLGRYQHL 261


>UniRef50_Q1YTE5 Possible methyltransferase n=1 Tax=gamma proteobacterium HTCC2207
           RepID=Q1YTE5_9GAMM
          Length = 260

 Score =  192 bits (488), Expect = 8e-48,   Method: Compositional matrix adjust.
 Identities = 98/248 (39%), Positives = 153/248 (61%), Gaps = 2/248 (0%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQK-LRVLDAGGGEGQTAIK 61
           DRNFDD++EKF+R +YG  KG +R A++W+DL   L ++  Q  LR+LD GGG GQ  + 
Sbjct: 7   DRNFDDLSEKFARKVYGGLKGDIRLAVIWRDLLAALPDLEIQAPLRILDIGGGLGQLTVA 66

Query: 62  MAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
           +A+ GHQV+  DLS QM++ A++ A  +GV D + +     Q +        DL++ HA+
Sbjct: 67  LAKLGHQVVYNDLSQQMLEVAQKLALEEGVMDKIIWCQQPYQTLKDQGLERFDLVMSHAL 126

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLS 181
           +EW+A+P  ++  L   L P G+LSL FYN + L+  N++ GNF+ +Q G      ++L+
Sbjct: 127 MEWLAEPELLIADLQQYLSPQGLLSLTFYNQNALVYRNLIRGNFNVLQ-GEFSAHPKSLT 185

Query: 182 PDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPY 241
           P  P  P  V  W+++AG      +G+RVFHDY+  +    +   A++++E R+  QEP+
Sbjct: 186 PGEPLQPQAVQEWVDQAGLVTDYSSGIRVFHDYVTTQRGGHENASAVIDMELRHSVQEPF 245

Query: 242 ITLGRYIH 249
             LGRYIH
Sbjct: 246 KWLGRYIH 253


>UniRef50_Q31JJ3 SAM-dependent methyltransferase n=3 Tax=Piscirickettsiaceae
           RepID=Q31JJ3_THICR
          Length = 259

 Score =  187 bits (475), Expect = 3e-46,   Method: Compositional matrix adjust.
 Identities = 103/259 (39%), Positives = 156/259 (60%), Gaps = 10/259 (3%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIK 61
           QDRNFD + +KF + +Y T KG+ R  +L +DL  +       KL + DAG G  Q +  
Sbjct: 4   QDRNFDKLVDKFEKKVYDTVKGEWRLKLLKEDLTPL---KKGNKLSIWDAGCGFAQISQW 60

Query: 62  MAERGHQVILCDLSAQMIDRAK-QAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
           +AE GH++ LCDLS QM+ RAK   A+A   +   +FI    Q+VA  +E P DL+LFHA
Sbjct: 61  LAESGHRLTLCDLSHQMLLRAKANFAQADLFA---EFIEGPVQEVAKQIE-PQDLVLFHA 116

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNF--DYVQAGMPKKKKR 178
           VLEW+A P   L+ +   ++PGG LSL+FYN + ++++N + G +   ++       K +
Sbjct: 117 VLEWLAQPEETLKIVTEQVKPGGYLSLLFYNRNSVVINNTLKGKWRLPFILEDAYLNKGK 176

Query: 179 TLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQ 238
            L+P  P+ P  V  WL++ G++I   TG+RVFHDY+  +  ++   E L+ LE R+CR+
Sbjct: 177 KLTPPNPQIPEVVCQWLQDWGFKIEIHTGIRVFHDYMTREVLEQSEMEDLMALEYRFCRE 236

Query: 239 EPYITLGRYIHVTARKPQS 257
             Y  + RYIH+ A+K  S
Sbjct: 237 PTYRNMARYIHILAKKKDS 255


>UniRef50_C5BHU7 SAM-dependent methyltransferase n=1 Tax=Teredinibacter turnerae
           T7901 RepID=C5BHU7_TERTT
          Length = 263

 Score =  178 bits (451), Expect = 2e-43,   Method: Compositional matrix adjust.
 Identities = 95/265 (35%), Positives = 159/265 (60%), Gaps = 14/265 (5%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEM-GPQKLRVLDAGGGEGQTA 59
           MQDRNFDD+A +F RN+YGT KG++R A+L +D      E+     L +LD G G+   +
Sbjct: 1   MQDRNFDDLAPRFKRNVYGTLKGRVRLAVLERDFREYAPELYADSPLDLLDLGAGQAPFS 60

Query: 60  IKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAA----------QDVASHL 109
           ++ A+ GH+++L D+S++M+  A Q A A   +++ + +H             +D+A  L
Sbjct: 61  LQFAQLGHRLVLADISSEMLAGA-QLAMADWAAEHRERVHAICHPLQQLAQPLRDMA--L 117

Query: 110 ETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQ 169
            +  D+++ HAVLEW+A+P  +   L + L+PGG+LSL FYN +GL   N++  NF    
Sbjct: 118 PSAFDVVICHAVLEWLAEPDRLYSHLANYLKPGGMLSLTFYNINGLAFKNLLRTNFHKFD 177

Query: 170 AGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALL 229
               +  + +L+P +P++P  V   L + G++I+ ++G+RVFHDY+ +  ++    EA++
Sbjct: 178 IDNFRSFRGSLTPTHPQEPHHVLRQLSKQGFEIVCRSGIRVFHDYILDPVERNREPEAIV 237

Query: 230 ELETRYCRQEPYITLGRYIHVTARK 254
             E  Y R+E +  + RYIHV  RK
Sbjct: 238 GKELEYSRRESFWPIARYIHVLGRK 262


>UniRef50_Q15TU3 Methyltransferase type 11 n=1 Tax=Pseudoalteromonas atlantica T6c
           RepID=Q15TU3_PSEA6
          Length = 252

 Score =  174 bits (441), Expect = 3e-42,   Method: Compositional matrix adjust.
 Identities = 97/254 (38%), Positives = 144/254 (56%), Gaps = 10/254 (3%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRV-LDAGGGEGQTAI 60
           +D+NFD IA+KF +NIYGTTKG+LR  +L   L +    +    L + LDAGGG G+ + 
Sbjct: 6   RDQNFDAIADKFEKNIYGTTKGRLRHELLQYHLRK---NIDFSTLSIALDAGGGTGEMSR 62

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
            + + G  V L D+S + +  AKQ       S  +  IH    D+    +   DL++ HA
Sbjct: 63  VLLQSGVNVTLSDISNEALAIAKQKCSE---SSALSVIH---SDILGLPDCEYDLVICHA 116

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
           VLEW+ DP   ++ L S+ + GG  SL F+N    ++ N++ GNFDYV+ GM  K +  L
Sbjct: 117 VLEWLNDPYVNVRKLISMTKIGGYFSLTFFNKDAQMLGNLLYGNFDYVKQGMKVKNRVRL 176

Query: 181 SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP 240
           SP+ P  P  V  +L++    I+   G+R FHDYL++   Q   YE L E E  +  +EP
Sbjct: 177 SPNKPLQPRAVIDFLQKQPVSIISTAGIRCFHDYLKDPTMQLSHYEQLKEAEMAFGDKEP 236

Query: 241 YITLGRYIHVTARK 254
           Y+ LG+Y H+  R+
Sbjct: 237 YMWLGKYFHILMRR 250


>UniRef50_Q21JL0 Methyltransferase type 12 n=1 Tax=Saccharophagus degradans 2-40
           RepID=Q21JL0_SACD2
          Length = 262

 Score =  173 bits (438), Expect = 6e-42,   Method: Compositional matrix adjust.
 Identities = 100/265 (37%), Positives = 146/265 (55%), Gaps = 13/265 (4%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDL-DRVLAEMGPQKLRVLDAGGGEGQTA 59
           M DRNFDD+A +F+RNIYG+ KG++R  +L +DL D V        + VLD G G+G  +
Sbjct: 1   MADRNFDDLAPRFARNIYGSHKGRVRLEVLKRDLCDYVPLFQNLAGVEVLDMGAGQGHFS 60

Query: 60  IKMAERGHQVILCDLSAQMIDRAK---------QAAEAKGVSDNMQFIHCAAQDVASHLE 110
           + +AE+G  V LCD+S +M+  AK         QA     +  +  F  CA Q +    E
Sbjct: 61  LGLAEQGAHVHLCDVSEKMLAMAKVRWQEICEAQAQAGMPIVGSATFTQCALQQLPVK-E 119

Query: 111 TPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQA 170
            P  L+L HAVLEW+ DPR     L   +  GG LS++ YNAHGL   N++ GNF     
Sbjct: 120 YP--LVLGHAVLEWLEDPRQGFGYLVDSVATGGYLSVIVYNAHGLAFKNLLRGNFKKFDR 177

Query: 171 GMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLE 230
              K  K +L+P  P  P Q+  W ++   +++G +G+RVF DY+ +K  +    + LL 
Sbjct: 178 NNFKAFKGSLTPISPLTPEQLMQWGKKLKLELVGFSGIRVFQDYILDKSIREADPDGLLV 237

Query: 231 LETRYCRQEPYITLGRYIHVTARKP 255
            E  Y R EP+  + RY+H   ++P
Sbjct: 238 KELEYSRLEPFRNMARYLHFVFKRP 262


>UniRef50_Q1QUF1 SmtA protein n=1 Tax=Chromohalobacter salexigens DSM 3043
           RepID=Q1QUF1_CHRSD
          Length = 268

 Score =  173 bits (438), Expect = 7e-42,   Method: Compositional matrix adjust.
 Identities = 104/261 (39%), Positives = 146/261 (55%), Gaps = 15/261 (5%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLR-VLDAGGGEGQTAI 60
           +DR FD +A+KF+  +YGT +G +R A+L   L R L    P   R  LD G G GQ + 
Sbjct: 16  RDRVFDGLADKFAAGLYGTPRGAIRLAVLEHVLPREL----PADARPALDVGAGLGQMSE 71

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
            +A RGH V L + S  M +RA        V+     +    Q +A     P  LI+ HA
Sbjct: 72  WLARRGHAVTLVEPSRDMRERAMDRVAGLAVT----ALDATWQTLAERAPGPWGLIVCHA 127

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNF----DYVQAGMPKKK 176
           VLEW+A+PR     L S+L PGG LS+M +N   L   N+V GN     D    G+ K++
Sbjct: 128 VLEWLAEPRDAFARLASLLAPGGYLSVMVFNRDALRFSNVVKGNLAKALDDRLEGLGKRQ 187

Query: 177 KRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYC 236
           +  L+P  P   AQV  W +EAG  ++  TGVR+FHDYL ++    +  + L+ELE RYC
Sbjct: 188 R--LTPISPLTDAQVRAWSQEAGLSLVSVTGVRIFHDYLADRDVSPEKLDQLIELECRYC 245

Query: 237 RQEPYITLGRYIHVTARKPQS 257
           +Q+P+  LGRY+H T  KP++
Sbjct: 246 QQDPHWRLGRYLHYTLFKPET 266


>UniRef50_B4RYI5 SAM-dependent methyltransferase n=2 Tax=Alteromonas macleodii
           RepID=B4RYI5_ALTMD
          Length = 247

 Score =  172 bits (437), Expect = 9e-42,   Method: Compositional matrix adjust.
 Identities = 94/253 (37%), Positives = 139/253 (54%), Gaps = 9/253 (3%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIK 61
            D  FD IAEKF+ NIYGTTKG+LR  +L      VLA    + L+ ++ GGG G     
Sbjct: 3   NDHIFDGIAEKFANNIYGTTKGRLRHTLLCD----VLAPYLARPLKAIEIGGGTGVMTAH 58

Query: 62  MAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
           +A  GH V+L D S+ ++ +A     A   SDN++  H   Q++        DL++ HAV
Sbjct: 59  IAAMGHDVVLTDASSDVLSKAAPLLNA---SDNIRIRHQYLQEIDD--LAAYDLVVCHAV 113

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLS 181
           LEW+  P   +  +   ++ G  LSL F+N    L  N + GNFDY+  GM  KK+  L+
Sbjct: 114 LEWLDAPFDAIDFIHKNMKRGARLSLSFFNQDANLFANAIYGNFDYIAKGMKAKKQVRLN 173

Query: 182 PDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPY 241
           P  P    +V  + E  G++++ K G+R FHDY+R+   Q   ++ LL LE +Y +  PY
Sbjct: 174 PKQPLGAMRVVDYCESLGFKVLDKAGIRCFHDYMRDISHQNSKFDELLALERQYHKMPPY 233

Query: 242 ITLGRYIHVTARK 254
           + LG+Y H+   K
Sbjct: 234 LWLGKYFHLILEK 246


>UniRef50_Q1QA01 Methyltransferase type 11 n=4 Tax=Moraxellaceae RepID=Q1QA01_PSYCK
          Length = 295

 Score =  170 bits (431), Expect = 4e-41,   Method: Compositional matrix adjust.
 Identities = 94/262 (35%), Positives = 150/262 (57%), Gaps = 10/262 (3%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQ---KLRVLDAGGGEGQTA 59
           DR+FD IA+ F + +YG  KG +R A+L +DL    A+   +    LR+LD G G  Q A
Sbjct: 32  DRSFDAIADHFEKKVYGGLKGDIRLAVLRRDLFEYCAQTSHKLGRPLRILDVGAGLAQIA 91

Query: 60  IKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSD---NMQFIHCAAQDVASHLETPV--- 113
           I++A +GH +++ D+SA M+D+A++ A     +D   N+ +  C  Q++   L       
Sbjct: 92  IELATQGHILVINDISANMLDKAQERAAQSSANDEKLNITWYVCPYQELEEKLADKTEKF 151

Query: 114 DLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMP 173
           DLI+ HA+LEW+A+P +V+      L   G LSL FYN       N++ GNF+ +     
Sbjct: 152 DLIMCHALLEWLAEPAAVMDFFDQQLSDNGALSLCFYNPASFDYRNLIMGNFNLLDNTEY 211

Query: 174 K-KKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELE 232
           K   K++L+P++P    +V  WL+   +Q +  +G+RVFHDY   K    +  EA++ +E
Sbjct: 212 KADSKKSLTPNHPVAKEEVEAWLQAHDYQTLIASGLRVFHDYSPLKRGGHNDPEAVIRME 271

Query: 233 TRYCRQEPYITLGRYIHVTARK 254
            RY + +PY  LGRY+H+ A +
Sbjct: 272 LRYSQLDPYKWLGRYLHLLATR 293


>UniRef50_A4XQ92 Methyltransferase type 11 n=17 Tax=Pseudomonas RepID=A4XQ92_PSEMY
          Length = 249

 Score =  169 bits (429), Expect = 6e-41,   Method: Compositional matrix adjust.
 Identities = 95/253 (37%), Positives = 144/253 (56%), Gaps = 6/253 (2%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M DR+FD++A +F+  IYG  KG +R A+L  DL   L +   + LRVLD G G G  ++
Sbjct: 1   MSDRHFDELATRFAEKIYGGAKGAIRLAVLQADLAEALPD---RPLRVLDVGAGLGHMSL 57

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
            +A RGH V L + +  M++ A+Q     G      FI    Q++   L+ P DL+L HA
Sbjct: 58  WLAGRGHDVTLAEPAEPMLEGARQRFAEAG--QRATFIQAPWQELLGRLDQPYDLVLCHA 115

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
           VLEW+A+P ++L  L  +   GG LSL FYN   L+  N++ G+F  ++      + ++L
Sbjct: 116 VLEWLAEPGAILPVLHQLTAKGGWLSLAFYNKDALIYRNLLKGHFRKLRKERFAGEGQSL 175

Query: 181 SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP 240
           +P  P DP ++   L E  WQ+  ++GVRVFHDY+ ++ Q +     LLE+E  + R   
Sbjct: 176 TPQRPLDPRELATQLGEH-WQVESRSGVRVFHDYMPQEFQAKAELIDLLEMELAHRRHPA 234

Query: 241 YITLGRYIHVTAR 253
           +  LGRY+H   R
Sbjct: 235 FAGLGRYLHWICR 247


>UniRef50_UPI0000E11711 methyltransferase type 11 n=1 Tax=Glaciecola sp. HTCC2999
           RepID=UPI0000E11711
          Length = 256

 Score =  169 bits (429), Expect = 7e-41,   Method: Compositional matrix adjust.
 Identities = 104/253 (41%), Positives = 146/253 (57%), Gaps = 8/253 (3%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
           D  FD I++KF++NIYGTTKGQLR A+L   L  +     P K ++LD+G G GQ A   
Sbjct: 10  DHGFDGISDKFAKNIYGTTKGQLRHALLCHHLSTLNLVNTPPK-QILDSGCGLGQMAEFF 68

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
           A+ GH V   D+S++ I  AKQ A+ K +S  + +   + Q V        DLI+ HAVL
Sbjct: 69  ADAGHHVEGMDISSESIAYAKQQAQDKHLS--IDYSVGSLQSVTKQ----YDLIINHAVL 122

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSP 182
           EW+ +P + ++ L   L PGG LSL F+N   L   N++ GNFDYV+ G+  KKK  L+P
Sbjct: 123 EWLQEPFAAIELLLKQLVPGGHLSLSFFNKDALTFGNLIYGNFDYVKKGLKVKKKVRLNP 182

Query: 183 DYPRDPAQVYLWLEE-AGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPY 241
             P     V  ++      +I+ + G+R  HDY+R+   Q   YEALL+ E  Y  Q PY
Sbjct: 183 QQPLSVQPVLSFINSLNNIEIIHQAGIRCIHDYMRDLSHQTTHYEALLDAEITYSTQPPY 242

Query: 242 ITLGRYIHVTARK 254
           + LG+Y H+  RK
Sbjct: 243 MWLGKYFHLVLRK 255


>UniRef50_A4VI82 Methyltransferase, putative n=5 Tax=Pseudomonadaceae
           RepID=A4VI82_PSEU5
          Length = 360

 Score =  167 bits (424), Expect = 2e-40,   Method: Compositional matrix adjust.
 Identities = 93/253 (36%), Positives = 144/253 (56%), Gaps = 6/253 (2%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M DR+FD++A +F+  IYG  KG +R A+L  DL  +L    P+ LRVLD G G G  ++
Sbjct: 112 MSDRHFDELATRFAEKIYGGAKGAIRLAVLQADLAEILP---PRPLRVLDIGAGLGHMSL 168

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
            +A++GH V L + +  M+  A+Q     G      FI    Q+V +H++   DL++ HA
Sbjct: 169 WLAQQGHAVTLAEPAEPMLQGARQQFADAG--QQATFIQAPWQEVQAHVDGRFDLVICHA 226

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
           VLEW+A+P+++L  L  +    G LSL FYN   L+  N++ G+F  +++     ++++L
Sbjct: 227 VLEWLAEPQAILPVLHRLTAADGWLSLAFYNRDALIYRNLLKGHFKKLRSQTYAGERQSL 286

Query: 181 SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP 240
           +P  P DP ++   L    WQ+   +GVRVFHDY+    Q R     L+E+E  Y R   
Sbjct: 287 TPQQPLDPRELAAQLAPH-WQVEFSSGVRVFHDYMPADFQARTEPADLIEMELAYRRHPT 345

Query: 241 YITLGRYIHVTAR 253
           +  LGRY+H   R
Sbjct: 346 FAGLGRYLHWLCR 358


>UniRef50_Q1N5H2 SAM-dependent methyltransferase n=1 Tax=Bermanella marisrubri
           RepID=Q1N5H2_9GAMM
          Length = 258

 Score =  164 bits (416), Expect = 2e-39,   Method: Compositional matrix adjust.
 Identities = 94/259 (36%), Positives = 144/259 (55%), Gaps = 10/259 (3%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
           DRNF+ ++ +F   IYGT KGQ+R A+L +DL   + +     L +LD G G+GQ +  +
Sbjct: 2   DRNFNGLSNRFKNQIYGTLKGQMRLALLEKDLSPYIEQ--THALNILDCGAGQGQFSSML 59

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNM--QFIHCAAQDVASHLETPV-----DL 115
           A+ GH ++L D+S +M+  A QA  A+   DN   Q I    Q +   L T       DL
Sbjct: 60  AQHGHSLVLNDVSDEMLAMA-QANLAELAPDNQTHQMITAPLQSLNEELHTRALPTQYDL 118

Query: 116 ILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKK 175
           +L HAVLEW+ +P + ++ L   ++  G+LSLMFYN H ++  N++ G++   Q      
Sbjct: 119 VLNHAVLEWLHEPFAAIEQLALWVKSDGILSLMFYNLHAIVWRNLMNGSWQRAQNTHFHH 178

Query: 176 KKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRY 235
            K  L P  P +PA V   +E  G+ I    G+R  HD++  + ++R   E  +ELE+  
Sbjct: 179 DKNNLMPQNPLNPADVVEKIESLGFSIELHRGIRCVHDHMFVEMRKRKTLEEFVELESDI 238

Query: 236 CRQEPYITLGRYIHVTARK 254
             + PY  LGRY+H+ ARK
Sbjct: 239 GLKAPYRDLGRYVHIVARK 257


>UniRef50_A5EV89 S-adenosylmethionine-dependent methyltransferase n=2
           Tax=Cardiobacteriaceae RepID=A5EV89_DICNV
          Length = 268

 Score =  138 bits (347), Expect = 2e-31,   Method: Compositional matrix adjust.
 Identities = 79/245 (32%), Positives = 130/245 (53%), Gaps = 5/245 (2%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           F++I + F + IY   KG++R A+L +DL   +    P+ L +LD G G GQ A+  A  
Sbjct: 17  FEEIGDHFLKQIYYNNKGRIRLAVLKRDLAPFMRT--PKPLEILDIGAGAGQMALWCAAF 74

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLET-PVDLILFHAVLEW 124
           GH+V L D S +++ +A++ A+ + ++    FI      +   L     D +L HAVLEW
Sbjct: 75  GHRVTLFDASERLLAQAQKQAQKESLNAQCTFICGEITQMPDVLGARQFDFVLSHAVLEW 134

Query: 125 VADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDY 184
           + D   + +     L+P G+LSLM+YN   L     V GNF YV +G+  KK   L+P Y
Sbjct: 135 LEDGAQLFERCQQYLKPNGLLSLMYYNRSALEFIQHVFGNFSYVDSGLVAKKTAKLTPKY 194

Query: 185 PRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPYITL 244
           PR    V   L      +  ++G+R F+DY++ + +  +  E+++  E     +  ++ +
Sbjct: 195 PRSSDWVAAQL--GALPLKKQSGIRCFYDYMKPEDRAANSIESIIAHELSLSLRREFLPV 252

Query: 245 GRYIH 249
            RYIH
Sbjct: 253 ARYIH 257


>UniRef50_A4BJS3 Putative SmtA protein n=1 Tax=Reinekea blandensis MED297
           RepID=A4BJS3_9GAMM
          Length = 229

 Score =  106 bits (264), Expect = 8e-22,   Method: Compositional matrix adjust.
 Identities = 73/212 (34%), Positives = 105/212 (49%), Gaps = 2/212 (0%)

Query: 44  QKLRVLDAGGGEGQTAIKMAERG-HQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAA 102
           +  +VLDAGGG GQ +    E+G   V   D+S QM+  A ++ +    +  +     + 
Sbjct: 18  ENWKVLDAGGGLGQMSHWFLEQGVTSVDYLDVSEQMVTAATESLQEYYEAGQLNASVGSV 77

Query: 103 QDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVA 162
            D+ S   +  D +  HAVLEW+  P +V+  L   +RPGG L LM YN H L+M +M+ 
Sbjct: 78  TDL-SEWPSDYDFVNVHAVLEWLEKPETVVPILCDRVRPGGYLGLMVYNRHMLMMRHMMR 136

Query: 163 GNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQR 222
           G      +G     KR L+P  P DP  V   L+  G  I+ + G+R F D   +   + 
Sbjct: 137 GTLKRAMSGNMAGDKRGLTPISPMDPQAVAKDLQACGMTILCQAGIRSFSDLTEKAVLEW 196

Query: 223 DCYEALLELETRYCRQEPYITLGRYIHVTARK 254
              EA+ + E   C Q PY  LGRY    ARK
Sbjct: 197 YTEEAVFDAEQALCEQRPYCDLGRYTLFIARK 228


>UniRef50_A3TKD6 Putative methyltransferase n=1 Tax=Janibacter sp. HTCC2649
           RepID=A3TKD6_9MICO
          Length = 258

 Score = 99.4 bits (246), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 82/247 (33%), Positives = 117/247 (47%), Gaps = 23/247 (9%)

Query: 26  RQAILWQDLDRVL----AEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDR 81
           R A +W  +D V+    AE+  + LRV+D GGG G  A+ +A  GH V + D S   +  
Sbjct: 18  RTAAMWAAVDEVVRARSAEL-ERPLRVIDLGGGTGGLAVPLAVAGHDVTVVDPSPDALAS 76

Query: 82  AKQ-AAEAKGVSDNMQFIHCAAQDVASHLETPV-----DLILFHAVLEWVADPRSVLQTL 135
            ++ AAEA+  S        A Q  A  LE+ V     DL+L H  LE+V DP++ L  +
Sbjct: 77  LRRRAAEAQASSRV-----SAVQGDADTLESLVGRDRPDLVLCHGTLEYVDDPQATLAQI 131

Query: 136 WSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPD-YPR--DPAQVY 192
             VL PGG+LSL+       ++   +AG F    A + +   R    D  PR  D A V 
Sbjct: 132 AGVLAPGGILSLVVPQRSAAVIARALAGQFVQALAALDRPDGRWGDADPVPRRFDRAGVV 191

Query: 193 LWLEEAGWQIMGKTGVRVFHDYLREKHQQRDC-YEALLELETRYCRQEPYIT---LGRYI 248
             +E +G  I G  G+R+F D +       D    ALL+LE        +     LG  +
Sbjct: 192 GLIEASGLTITGAHGIRIFSDLVPSALVDSDADRAALLDLERAVAAHPEFAVLADLGTSL 251

Query: 249 HVTARKP 255
           HV A +P
Sbjct: 252 HVIASRP 258


>UniRef50_B5L6J9 Methyltransferase n=1 Tax=Micromonospora chalcea RepID=B5L6J9_MICCH
          Length = 263

 Score = 96.7 bits (239), Expect = 7e-19,   Method: Compositional matrix adjust.
 Identities = 72/245 (29%), Positives = 124/245 (50%), Gaps = 14/245 (5%)

Query: 20  TTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMI 79
           T  G+LR +++  ++ R    +G + LRVLD  GG G+ A+ +A RGH V + D +   +
Sbjct: 23  TPWGRLRYSVVEANVAR---HLGDRPLRVLDVAGGNGRDAVPIAARGHHVTVLDSAPVSL 79

Query: 80  DRAKQAAEAKGVSDNMQFIHCAAQDVASHLE-TPVDLILFHAVLEWVADPRSVLQTLWSV 138
             A++ A  +GV++ ++     A DV         DL+L H +L++VADP  V++ L  V
Sbjct: 80  AMAQRLAADEGVAERIEIREGDAHDVPELFAGQEFDLLLCHNLLQYVADPAVVIRGLVKV 139

Query: 139 LRPGGVLSLMFYNAHGLLMHNMVAG-NFDYVQAGMPKKKKRTLSPDYPRDPA-----QVY 192
           L+PGG LS++  NA+ + +   V   + D     +  + K+   P Y RD A     Q+ 
Sbjct: 140 LKPGGSLSVVGPNAYAVPLEAAVRELDLDAALRAVTARTKQV--PVYGRDVAVLTADQIG 197

Query: 193 LWLEEAGWQIMGKTGVRVFHDYLREKHQQRD--CYEALLELETRYCRQEPYITLGRYIHV 250
             L ++G +I+G  GV    + + +   + D   +  L +LE     + PY    R  H+
Sbjct: 198 ADLRDSGLEIVGHYGVINICNVIADNDVKSDPEFFARLEKLELALADRMPYPLTARNFHL 257

Query: 251 TARKP 255
             ++P
Sbjct: 258 VGQRP 262


>UniRef50_D1VJQ5 Methyltransferase type 12 n=1 Tax=Frankia sp. EuI1c
           RepID=D1VJQ5_9ACTO
          Length = 296

 Score = 95.5 bits (236), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 73/230 (31%), Positives = 108/230 (46%), Gaps = 22/230 (9%)

Query: 48  VLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVS--------DNMQFIH 99
           V+DAGGG G  A+ +AERGH+V++ D S   +    + A   GV+        D  +   
Sbjct: 67  VVDAGGGSGGFAVPLAERGHRVLVVDPSQDALAALARRAADAGVAARVTGRQGDLSELSA 126

Query: 100 CAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHN 159
               D+A+      DL+L HAVL+ V DPR  L T+  VLRPGG LSL+     G ++  
Sbjct: 127 VVGPDLAAAGGA--DLLLCHAVLDRVDDPRRALATVLRVLRPGGWLSLLVPGRAGTVLAR 184

Query: 160 MVAGNFDYVQAGM----PKKKKRTLSPDYPR-DPAQVYLWLEEAGWQIMGKTGVRVFHDY 214
            +AG FD     +    P    R L+ +  R D  ++   +  AG +++   GVRV  D 
Sbjct: 185 ALAGRFDEAAQALAGPYPPAPGRRLAGETHRFDTDEIVGLVRAAGAEVVAVHGVRVLTDL 244

Query: 215 LR-------EKHQQRDCYEALLELETRYCRQEPYITLGRYIHVTARKPQS 257
                    E+       E L +LE     + PY  L   +HV AR+ ++
Sbjct: 245 ATPPAGGGDEREPAAGWAERLADLEAAVATRPPYRDLAAQLHVLARRTEA 294


>UniRef50_A3TLQ5 S-adenosylmethionine-dependent methyltransferase n=1 Tax=Janibacter
           sp. HTCC2649 RepID=A3TLQ5_9MICO
          Length = 259

 Score = 94.0 bits (232), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 66/241 (27%), Positives = 118/241 (48%), Gaps = 11/241 (4%)

Query: 23  GQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRA 82
           G+LR A++   +D  +AE G + LR+LD GG +G   +  A RGHQ+ + D +    DR 
Sbjct: 20  GRLRFALIGDAIDEAIAEFGDRTLRILDVGGADGFETLPYAIRGHQLTVADPAEGFFDRG 79

Query: 83  KQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW--VADPRSVLQTLWSVLR 140
           ++AAE  GVSD ++++    +++    +T  D+++ H VL +       + + TL  +  
Sbjct: 80  REAAEQLGVSDRVRWVSAGLEELPMAGDTAYDVVVCHFVLHYRPAGSLGADVATLSRLTA 139

Query: 141 PGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDP-----AQVYLWL 195
           P GV+S+   N  GL++  +        +A + +  +   S  +  D       +V   L
Sbjct: 140 PDGVISIACPNEAGLVLRTLTREGPAAARAELDETTQ--FSHTFGHDSQKVGREEVAAAL 197

Query: 196 EEAGWQIMGKTGVRVFHDYLREKHQQRD--CYEALLELETRYCRQEPYITLGRYIHVTAR 253
            E G       GVR+ +D +     + D   ++ LL LE   CR++PY  +     +TA+
Sbjct: 198 HENGLVETEWMGVRIANDLIVHDEMKHDPVYFQQLLALERDLCRRDPYRGIAALWQLTAK 257

Query: 254 K 254
           +
Sbjct: 258 R 258


>UniRef50_D1V817 Methyltransferase type 12 n=2 Tax=Frankia RepID=D1V817_9ACTO
          Length = 276

 Score = 93.6 bits (231), Expect = 7e-18,   Method: Compositional matrix adjust.
 Identities = 69/247 (27%), Positives = 118/247 (47%), Gaps = 16/247 (6%)

Query: 20  TTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMI 79
           T +G +RQ ++ + L   L  +     R+LD GGGEG  A  +A  G++V +CD   +M+
Sbjct: 32  TLRGAVRQRLVTRAL---LTHLPTPPGRILDVGGGEGTQARALARLGYEVTICDPDPEML 88

Query: 80  DRAKQ--AAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWS 137
            +A +  +     V D +  +H    D AS +    D +L H VL ++ DP ++L  L  
Sbjct: 89  RQADERLSGADAAVRDRITLVHGDGHDAASLVGGGWDGVLCHGVLMYLTDPAALLHVLAD 148

Query: 138 VLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGM---PKKKKRTLS-------PDYPRD 187
           V   GGV+S++  NA  L +   + G +    + +   P+    T++       P    D
Sbjct: 149 VTGAGGVISVVGKNATALALRAGLQGRWRDTLSLLDEEPRAAAGTVTEIGNLGVPSRGDD 208

Query: 188 PAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPYITLGRY 247
           P Q+   L  AG + +   G+RV  D+L +     D  + ++E E R   ++PY  + R 
Sbjct: 209 PHQIRDLLSAAGTEPLAWYGIRVLTDHLGDTPPGPD-LDTVVEAEWRAGERDPYRQVARL 267

Query: 248 IHVTARK 254
            H+  R+
Sbjct: 268 YHLIHRR 274


>UniRef50_C7QBJ1 Methyltransferase type 12 n=15 Tax=Actinomycetales
           RepID=C7QBJ1_CATAD
          Length = 263

 Score = 92.8 bits (229), Expect = 9e-18,   Method: Compositional matrix adjust.
 Identities = 78/238 (32%), Positives = 110/238 (46%), Gaps = 13/238 (5%)

Query: 29  ILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEA 88
           +LWQ L  VL   GP+   VLD GGG G  A+ +AE GH+V + D S   +   ++ A  
Sbjct: 30  VLWQALRTVLDASGPRD--VLDVGGGTGGFAVPIAELGHRVTVVDPSPDALAALERRAAE 87

Query: 89  KGVSDNMQFIHCAAQDVASHLE----TPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGV 144
            GV    + +     D+A  LE      VDL+L H VLE   DP + L T+  VLRPGGV
Sbjct: 88  SGVPK--EALRAVQGDLAGLLEHVEPGSVDLVLCHGVLEMADDPAAGLATVADVLRPGGV 145

Query: 145 LSLMFYNAHGLLMHNMVAGNFDYVQAGM--PKKKKRTLSPDYPR-DPAQVYLWLEEAGWQ 201
           +SL+  N    ++   + G+F   +  +  P  +     P   R D  Q+   L EA   
Sbjct: 146 VSLLAANRTAAVVARALGGHFAEARRALADPTGRFGAQDPLAARFDEEQLSRLLREARLT 205

Query: 202 IMGKTGVRVFHDYLREKHQQRDCYEA--LLELETRYCRQEPYITLGRYIHVTARKPQS 257
           +    GVRVF D +       D   A  L  LE     +  +  +   +H+ ARK  S
Sbjct: 206 VQSVHGVRVFTDLVPGALVDADPQAASDLAALEAAVADRPEFRAVAGRLHLLARKIAS 263


>UniRef50_B4V3L4 Methyltransferase n=17 Tax=Streptomyces RepID=B4V3L4_9ACTO
          Length = 235

 Score = 92.0 bits (227), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 68/214 (31%), Positives = 101/214 (47%), Gaps = 7/214 (3%)

Query: 44  QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMID--RAKQAAEAKGVSDNMQFIHCA 101
           Q+LRVLD G G+G  A+++A  GH+V   +    M+D  RA  A E  G+ D ++ I   
Sbjct: 17  QRLRVLDVGMGQGTQALRLARAGHKVTGLEKDPGMLDVARAALAGEPAGIQDRVELIEGD 76

Query: 102 AQDVASH-LETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNM 160
            ++  +H L    D++L H VL +V +P ++L  L  +L PGG+LSL+  N   L M   
Sbjct: 77  GRETGAHFLPGSFDIVLCHGVLMYVPEPDAMLAGLARMLAPGGLLSLLVRNGDALAMRPG 136

Query: 161 VAGNFDYVQAGMPKKK-KRTLSPDYPRDP-AQVYLWLEEAGWQIMGKTGVRVFHDYLREK 218
           + G++    A          L  D   D  + +   L   G  +    GVRVF D     
Sbjct: 137 LDGDWSGALAAFDTTDYTNRLGLDVRADRLSGLTATLSGIGAPLQSWYGVRVFTDGTEAG 196

Query: 219 HQ--QRDCYEALLELETRYCRQEPYITLGRYIHV 250
            Q    D  E LL  E R  R +PY  +   +H+
Sbjct: 197 EQLPPEDELERLLAAEERAGRSDPYRGVAALLHL 230


>UniRef50_Q2JD64 Methyltransferase type 11 n=2 Tax=Frankia RepID=Q2JD64_FRASC
          Length = 270

 Score = 89.4 bits (220), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 69/227 (30%), Positives = 104/227 (45%), Gaps = 26/227 (11%)

Query: 21  TKGQLRQAILWQDLDRVLA---------EMGPQKLRV----LDAGGGEGQTAIKMAERGH 67
           T   LRQA +W  L  VL           + P    +    +DAGGG G  A+ +A  G+
Sbjct: 6   TGADLRQAAIWHGLRTVLPGSAAGVPAWSVAPTATAIPPIIVDAGGGSGGFAVPLAVEGY 65

Query: 68  QVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHL--ETPVDLILFHAVLEWV 125
            VI+ D S   +   ++ A+ +GV+D +        D+   +  ET  DL+L H+VL+ V
Sbjct: 66  LVIVVDPSPDALAALRRRADERGVADRVTAEQGDLADLTGIVGAET-ADLLLCHSVLDVV 124

Query: 126 ADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYP 185
            DP + L     VLRPGGVLSL+       ++   +AG F+  QA +  +         P
Sbjct: 125 DDPEAALAGALRVLRPGGVLSLVVAGRAATVLARALAGRFEQAQAVLTGQGA-----GAP 179

Query: 186 RDP-----AQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEA 227
           R P     A++   +  AG  ++   GVRVF D +       D + A
Sbjct: 180 RTPAGFTTAEIVALVNAAGADVVDVHGVRVFADLVPGARVDSDPFTA 226


>UniRef50_B3TMR6 SAM-dependent methyltransferase n=1 Tax=Actinomadura kijaniata
           RepID=B3TMR6_9ACTO
          Length = 260

 Score = 86.7 bits (213), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 69/243 (28%), Positives = 117/243 (48%), Gaps = 10/243 (4%)

Query: 20  TTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMI 79
           T  GQLR +++  +L R    +G + LRVLD  GG G+ A+++A RGH V + D +   +
Sbjct: 20  TPWGQLRYSVVEANLAR---HLGDRPLRVLDVAGGNGRDAVRLALRGHHVTVLDSAPISL 76

Query: 80  DRAKQAAEAKGVSDNMQFIHCAAQDVASHL-ETPVDLILFHAVLEWVADPRSVLQTLWSV 138
             A++ A  +GV+D ++     A DV     +   DL+L H +L++V D   V++ +   
Sbjct: 77  AGAEELAAERGVADRIEVREGDAHDVPELFPDQDFDLLLCHNLLQYVPDRAVVVRAIARR 136

Query: 139 LRPGGVLSLMFYNAHGLLMHNMVAG-NFDYVQAGM--PKKKKRTLSPDYPRDPA-QVYLW 194
           LRPGG+LS++  NA  + +   V   + D     +    K  +    D P   A ++   
Sbjct: 137 LRPGGLLSVVGPNAVAVPLEAAVRELDLDAALRAVDSSTKPNQVYGADVPVLTADEIGGH 196

Query: 195 LEEAGWQIMGKTGVRVFHDYLREKHQQRD--CYEALLELETRYCRQEPYITLGRYIHVTA 252
             +AG  ++G  GV      + +   + D   +  L +LE     + PY +  R  H+  
Sbjct: 197 FRDAGLDVVGHHGVLSVCHLIADNEIKYDPEFFARLEKLEHTLAERAPYPSTARMFHLVG 256

Query: 253 RKP 255
           R P
Sbjct: 257 RLP 259


>UniRef50_A6WCY9 Methyltransferase type 12 n=2 Tax=Actinomycetales
           RepID=A6WCY9_KINRD
          Length = 265

 Score = 85.5 bits (210), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 62/209 (29%), Positives = 101/209 (48%), Gaps = 8/209 (3%)

Query: 29  ILWQDLDRVLAEMGPQ----KLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQ 84
           +LW+ + R+LA+        +L V+D GGG G  A+++A  GH+V++ D S   +   ++
Sbjct: 31  VLWEGVQRLLADAAAAPGAGELTVVDLGGGTGGLAVRVAALGHRVVVVDPSPDALAALER 90

Query: 85  AAEAKGVSDNMQFIHCAAQDVASHLETP-VDLILFHAVLEWVADPRSVLQTLWSVLRPGG 143
                G+SD ++ +   A D+A+ LE    D++L H VLE V DPR+ L+     LRPGG
Sbjct: 91  RTVEAGLSDRVRALQGDATDLAAVLEPGRADVLLCHGVLEVVDDPRAALRAAHDALRPGG 150

Query: 144 VLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPR---DPAQVYLWLEEAGW 200
            LSL+       ++  +++G+ D     +     R    D  R   D A      + AG+
Sbjct: 151 RLSLLVAQWPASVLARVLSGHLDQALHVLSDADHRWSGHDPLRRRFDRASATALAQGAGF 210

Query: 201 QIMGKTGVRVFHDYLREKHQQRDCYEALL 229
            +    G R F D +     + D    LL
Sbjct: 211 TVTAVEGTRTFSDVVPSTRTESDADVELL 239


>UniRef50_C0ZNJ7 Putative methyltransferase n=1 Tax=Rhodococcus erythropolis PR4
           RepID=C0ZNJ7_RHOE4
          Length = 274

 Score = 85.5 bits (210), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 72/246 (29%), Positives = 114/246 (46%), Gaps = 13/246 (5%)

Query: 23  GQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRA 82
           G+LR  +   +LD  +   G   LRVLD GGG+G  +I +A  G+QV L D S  M+D A
Sbjct: 24  GRLRYTVARANLDTYVG--GRSGLRVLDLGGGDGLESILLARNGNQVTLVDSSPAMLDIA 81

Query: 83  KQAAEAKGVSDNMQFIHCAAQDVASHLET-PVDLILFHAVLEWVADPRSVLQTLWSVLRP 141
              A+A GVS +M F++    D+   + T   D++L H VL+++      L  + + L  
Sbjct: 82  SGRADAAGVSASMTFVNSEVLDLPRSIATGSFDVVLLHNVLQYLPQGIGALPAVTAPLAD 141

Query: 142 GGVLSLMFYNAHGLLMHNMVAGNFDYVQA----GMPKKKKRTLSPDYPRDPA-QVYLWLE 196
           GG+ S++  N     +    A   D  +A    G  + +  T   D     A  +   +E
Sbjct: 142 GGIFSVISINKFSEPIA-AAARRADPTEALNLLGESRYRSVTFDSDLTMFAAGDIIDAIE 200

Query: 197 EAG-WQIMGKTGVRVFHDYLREKHQQRD--CYEALLELETRYCRQEPYITLGRYIHVTAR 253
             G +  +   G+R F D++    ++ D   Y AL  LE     + PY+   R   +  R
Sbjct: 201 ATGDFGDVNHYGIRCFSDFIAADDEKWDPEFYSALEALELASTARWPYMHTARLFQIIGR 260

Query: 254 KPQSKD 259
           +  SKD
Sbjct: 261 R-ASKD 265


>UniRef50_D2SA73 Methyltransferase type 11 n=1 Tax=Geodermatophilus obscurus DSM
           43160 RepID=D2SA73_9ACTO
          Length = 252

 Score = 79.7 bits (195), Expect = 9e-14,   Method: Compositional matrix adjust.
 Identities = 71/242 (29%), Positives = 102/242 (42%), Gaps = 18/242 (7%)

Query: 26  RQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQA 85
           R   +W  LD ++A   P  L+VLD GGG G  A+ +A  GH V + D SA  +    + 
Sbjct: 17  RAVAVWAALDPLVAAGRP--LQVLDVGGGSGNFAVPLARLGHDVTVVDPSADALATLNRR 74

Query: 86  AEAKGVSDNMQFIHCAAQDVASHLETPV--------DLILFHAVLEWVADPRSVLQTLWS 137
           AE  GV   ++ +      +  H   P         DL L H+VLE V DP + L+ L  
Sbjct: 75  AENAGVGARVRGVQGDGDQL--HQVVPAGETGEGSYDLALCHSVLEVVDDPAATLRELAR 132

Query: 138 VLRPGGVLSLMFYNAHGLLMHNMVAGN----FDYVQAGMPKKKKRTLSPDYPRDPAQVYL 193
            LRPGG  S+   N  G ++   VAG+       ++   P  ++          P  +  
Sbjct: 133 ALRPGGTASVASANRAGAVLARAVAGHPVEALALLEDRDPAPRRARRPARRRFSPDDLIT 192

Query: 194 WLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPYITLGRYIHVTAR 253
            +E AG Q     GV V  D L          EA+  LE       PY  +   +H+ A 
Sbjct: 193 LVEAAGLQPGTWRGVSVVSDLLDVTSGADP--EAVRRLELALAGSSPYRDVAAGLHLLAT 250

Query: 254 KP 255
           +P
Sbjct: 251 RP 252


>UniRef50_A8M0L9 Methyltransferase type 12 n=1 Tax=Salinispora arenicola CNS-205
           RepID=A8M0L9_SALAI
          Length = 269

 Score = 79.3 bits (194), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 71/245 (28%), Positives = 122/245 (49%), Gaps = 12/245 (4%)

Query: 20  TTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMI 79
           T  G+LR  ++   +DR +  +     RVLDAGG +G  ++++A+RGH V + D +  ++
Sbjct: 25  TPWGRLRYRLVAHTVDRAVRRLS-GTCRVLDAGGADGADSLRLAQRGHHVTIVDHAPALL 83

Query: 80  DRAKQAAEAKGVSDNMQFIHCAAQDVASHL----ETPVDLILFHAVLEWVADPRSVLQTL 135
            RA+  A A GV D++    CA  D    L    E   DL+L H VL ++ D  + +  L
Sbjct: 84  ARARARARAAGV-DHLVRTVCAGVDEVPELRRTGEVGFDLVLCHNVLHYLPDTPAAVAGL 142

Query: 136 WSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKK---KRTLSPDYPRDPAQ-V 191
            + +RPGG++S++  N    L+   V  +      G+   +     T   D  R  A+ V
Sbjct: 143 ATAVRPGGLISVLAPNPAMDLLAIAVRRSSPAEAFGLLDAEALFSETFEHDMLRLEAEDV 202

Query: 192 YLWLEEAGWQIMGKTGVRVFHDYL-REKHQQRDCYEALLE-LETRYCRQEPYITLGRYIH 249
              LE++G  +  + G+R   D +  ++ +    + A LE LE   C +EPY+ + R+  
Sbjct: 203 AAALEKSGCTVTDRFGIRCATDLIANDELKHTPAFFADLERLELALCDREPYLRMARFWQ 262

Query: 250 VTARK 254
           + A +
Sbjct: 263 LLATR 267


>UniRef50_A6WDP8 Methyltransferase type 12 n=1 Tax=Kineococcus radiotolerans
           SRS30216 RepID=A6WDP8_KINRD
          Length = 268

 Score = 73.9 bits (180), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 75/254 (29%), Positives = 120/254 (47%), Gaps = 28/254 (11%)

Query: 23  GQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRA 82
           G+LR  ++ + L    AE+G + LRVLDAGGG+G+ A++ A  GH V + D S +M+  A
Sbjct: 20  GRLRYRVVARVLREWCAELGGEPLRVLDAGGGDGRDAVQFALAGHAVTVLDRSPEMLALA 79

Query: 83  KQAAEAKGVSDNMQFIHCAAQDVAS------HLE---TPVDLILFHAVLEWVAD---PRS 130
           + AA A GV D +  +    +D+ +      H E      D++L H VL+        R+
Sbjct: 80  RAAAGAAGVGDRLHTVAADLEDLTALAALTRHREGGSGSFDVVLCHDVLQHRRSHEQVRA 139

Query: 131 VLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGN-------FDYVQAGMPKKKKRT--LS 181
            + TL S +RPGG++SL+  +    ++  ++           D  +A  P   +    LS
Sbjct: 140 DVATLTSSVRPGGLVSLLAPDPAADVVATVLREGPAAAWIVLDAERALDPGTGRSALRLS 199

Query: 182 PDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEA-LLELETRYCRQEP 240
           P++  D       L EAG  +  + G+      L E  +  D   A L ELE    R+E 
Sbjct: 200 PEFAEDA------LTEAGCDVAQRAGILAVTTLLEEAERVDDRAAADLEELEVELSRREQ 253

Query: 241 YITLGRYIHVTARK 254
           +    RY  +  R+
Sbjct: 254 FRGTARYWLIGGRR 267


>UniRef50_B1BEI5 Probable S-adenosylmethionine-dependent methltransferase n=8
           Tax=Clostridium perfringens RepID=B1BEI5_CLOPE
          Length = 267

 Score = 72.0 bits (175), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 58/238 (24%), Positives = 112/238 (47%), Gaps = 25/238 (10%)

Query: 37  VLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQ 96
           ++ E  PQ+ ++LD G G G+ +I++ +RG++V L DLS + ID AK   E+ G+  N  
Sbjct: 35  MIKEYFPQEGKILDIGSGPGRYSIELLKRGYEVSLMDLSEKSIDMAKNNIESMGLKAN-D 93

Query: 97  FIHCAAQDVASHLETPVDLILFHAVLEWVA---DPRSVLQTLWSVLRPGGVLSLMFYNAH 153
           +I   A  +    +   D IL    +  V    D   +L+    +L+PGG++ + + N+ 
Sbjct: 94  YICGDALYLDFIKDNTFDGILLMGPMYHVKSREDRIRILENCMRILKPGGIILIAYINSL 153

Query: 154 GLLM------------HNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQ 201
           G+L              N +   FD  + G  +++  + +  Y   P +    + E G+ 
Sbjct: 154 GVLKVGLSDFPQEYKDINKIYDLFD--EKGFSQEE--SFTETYFTVPEKAISEVNEVGFN 209

Query: 202 IMGKTGVRVFHD----YLREKH-QQRDCYEALLELETRYCRQEPYITLGRYIHVTARK 254
           I+ + G   F      Y+ + + + ++ Y  LL++ T  C  E +     ++ + A+K
Sbjct: 210 ILSRAGAESFLSGQAFYMTKYYLEDKEIYFNLLKVATEKCEDERFRDSTEHLIIVAKK 267


>UniRef50_UPI0001B4EB31 methyltransferase n=1 Tax=Streptomyces sp. C RepID=UPI0001B4EB31
          Length = 262

 Score = 71.6 bits (174), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 67/257 (26%), Positives = 120/257 (46%), Gaps = 11/257 (4%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
            FD +   ++ +   + +G+LR  ++ +   R+LAE+     R+LD G G G+  +++A 
Sbjct: 6   GFDSVGAAYAAH-SDSARGRLRHDLVER---RLLAELPAAPARILDVGCGNGEMTLRLAA 61

Query: 65  RGHQVILCD-LSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
            G++V   D  +  +   A + A    ++D +Q ++ A  D  S    P D +  H VL 
Sbjct: 62  AGYRVTGVDPAATMLAAAADRLAARPELADRVQLVN-AGLDSLSLDGKPFDGVCCHGVLM 120

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLS-- 181
           ++ DP   +  L  ++ PGG+LS++  N+  + +   +AG+ +     +  +  R++   
Sbjct: 121 YLDDPGEAVVRLAGLVAPGGLLSILAKNSRAVGVREALAGDSETACRLIVSQADRSVGNL 180

Query: 182 --PDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREK-HQQRDCYEALLELETRYCRQ 238
                  DP  +     E G       GVR+FHD+  +        Y A LELE     +
Sbjct: 181 GRETRGDDPDALDRLAAEHGLSPQPWQGVRIFHDHFDDTWAPDPAAYAAALELEWAASSR 240

Query: 239 EPYITLGRYIHVTARKP 255
            PY  LG  +H  AR+P
Sbjct: 241 SPYRDLGHLVHTLARRP 257


>UniRef50_C9NJ50 Methyltransferase type 12 n=8 Tax=Streptomyces RepID=C9NJ50_9ACTO
          Length = 252

 Score = 71.6 bits (174), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 69/246 (28%), Positives = 112/246 (45%), Gaps = 16/246 (6%)

Query: 22  KGQLRQAILWQ----DLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQ 77
           +  LR A++W+     L+R +   G + L VLD GGG G  A+ +A  GH+V + D S  
Sbjct: 8   RASLRTAVVWEVLKDALERRVKATGREALDVLDTGGGTGNFAVPVARLGHRVTVVDPSPN 67

Query: 78  MIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLET----PVDLILFHAVLEWVADPRSVLQ 133
            +   ++ A+  GV+D ++ +     D+    E       D +L H VLE+V DP   ++
Sbjct: 68  ALFALERRADEAGVADRVRGVQG---DILGLFEVVDRAGYDAVLCHGVLEYVDDPAEGVR 124

Query: 134 TLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPD-YPR--DPAQ 190
                LRP G LSL+     G ++   +AG+F   +  +     R  + D  PR     Q
Sbjct: 125 NAVDALRPSGALSLLGAGLGGAVLARALAGHFAEARQALTDPDGRWGAGDPVPRRFTADQ 184

Query: 191 VYLWLEEAGWQIMGKTGVRVFHDYLRE--KHQQRDCYEALLELETRYCRQEPYITLGRYI 248
           +   ++ AG ++    GVRVF D +       +    E LL LE        + ++   +
Sbjct: 185 LTGLVDAAGVEVGAVHGVRVFADLVPGVLVDTEPGAMEELLRLEAAVAELPAFHSVATQL 244

Query: 249 HVTARK 254
           HV   K
Sbjct: 245 HVLGEK 250


>UniRef50_C8XH01 Methyltransferase type 11 n=1 Tax=Nakamurella multipartita DSM
           44233 RepID=C8XH01_NAKMY
          Length = 262

 Score = 71.2 bits (173), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 49/171 (28%), Positives = 82/171 (47%), Gaps = 4/171 (2%)

Query: 45  KLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQD 104
            +RVLD GGG G  A+ +A  G  V + D S   +    + A+  GV+D +  +   A  
Sbjct: 42  AVRVLDVGGGSGTRAVPLAVLGCSVTVVDASVNSLAILHRRAQDAGVADRVVGVQADADR 101

Query: 105 V-ASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAG 163
           + A      +DL+L H +LE V DP +V+  +   +RPGG +S++     G ++   +AG
Sbjct: 102 LEAIAAPASIDLVLCHHLLEAVDDPAAVMGAVVRTVRPGGYVSILVAGRLGAVLGQTMAG 161

Query: 164 NFDYVQAGMPKKKKRTLSPDYPR---DPAQVYLWLEEAGWQIMGKTGVRVF 211
            F+  +  +     R+ + D  R   D   V   ++  G Q+   +GV V 
Sbjct: 162 RFEAARELLTGPDGRSGAADTLRRRFDVPGVRALVDSVGLQVESVSGVGVL 212


>UniRef50_A4FIW0 Methyltransferase n=3 Tax=Actinomycetales RepID=A4FIW0_SACEN
          Length = 272

 Score = 69.7 bits (169), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 64/266 (24%), Positives = 117/266 (43%), Gaps = 17/266 (6%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M D  +  +A++F+   Y + KG++R  +L Q L   L  + P    VLD GGG G  + 
Sbjct: 1   MDDDTWAGLADQFADGAYASVKGRVRTYVLHQQL---LEHLPPPPAPVLDVGGGAGHQSF 57

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVD-----L 115
            +A+ G+ V L D S+ M+D+A+Q  +   + D  Q      +    + +  V+      
Sbjct: 58  PLAQAGYDVTLLDPSSAMLDKARQRLDR--LPDEAQRRVTLLEADGENADEAVNGRRFAA 115

Query: 116 ILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKK 175
           +L H VL +   P  ++  L      GG++S+M  NA+ + +   +   +D   A    +
Sbjct: 116 VLCHGVLGYQEQPEPLVDQLCRCAAAGGIVSIMAGNANAMAVRPALERRWDDALASFDAR 175

Query: 176 KKRTL--SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEA-----L 228
            +  +   P       ++   +   G + +   GV +F D+L     + D  ++      
Sbjct: 176 GEIGVLGVPTRADTVEELSELVRSRGVEPLRWYGVWLFVDWLDFSGAELDPGDSEQVAAA 235

Query: 229 LELETRYCRQEPYITLGRYIHVTARK 254
             +E    R++PY  L R  H+  RK
Sbjct: 236 AAVELEAGRRDPYRGLSRVFHLVGRK 261


>UniRef50_Q8TJW5 Putative uncharacterized protein n=1 Tax=Methanosarcina acetivorans
           RepID=Q8TJW5_METAC
          Length = 306

 Score = 68.2 bits (165), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 47/135 (34%), Positives = 70/135 (51%), Gaps = 4/135 (2%)

Query: 29  ILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEA 88
           I ++   R L    P+K R+LD GGG G+ +I +A +GH V L DLS++ I  AK  AE 
Sbjct: 62  IEYETTRRYLDIYLPKKSRILDVGGGPGRYSIYLASQGHNVTLFDLSSKNILLAKAKAEE 121

Query: 89  KGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRS---VLQTLWSVLRPGGVL 145
           +GV     FIH  A ++  H +   D IL       + D      V+    +VL+PGG+L
Sbjct: 122 QGVHLE-GFIHGNALELDHHTKGRFDAILCMGPSYHLTDESQRHIVIDKCVNVLKPGGIL 180

Query: 146 SLMFYNAHGLLMHNM 160
            + F +A   ++  M
Sbjct: 181 FVSFISAFAPIIDMM 195


>UniRef50_Q47QY4 Putative methyltransferase n=1 Tax=Thermobifida fusca YX
           RepID=Q47QY4_THEFY
          Length = 252

 Score = 67.4 bits (163), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 69/254 (27%), Positives = 115/254 (45%), Gaps = 18/254 (7%)

Query: 14  SRNIYGTTKGQLRQAILWQDLDRVLAEMGPQ---KLRVLDAGGGEGQTAIKMAERGHQVI 70
           S+   G      R A++W+ L   LA +  +    L ++DAGGG G  A+ +A  GH+V 
Sbjct: 4   SKVSSGRASSAARTAVVWEALTAELARLAEEFVEPLNIVDAGGGTGGAAVPLARLGHRVT 63

Query: 71  LCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHL-ETPVDLILFHAVLEWVADPR 129
           + D S   +   ++ A   GV  N   +   A+ +   L E    L+L H V+E V DP 
Sbjct: 64  VVDSSPDSLAALERRAAEAGVRVNA--VQGDAEGLRELLPEASAHLVLVHNVVEHVDDPL 121

Query: 130 SVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDP- 188
           + L+ + S+ +P G +S++  NA   ++H  +AG+     A +   + R      P DP 
Sbjct: 122 TALRDVVSITQPRGAVSVLATNAVAAVLHRALAGHLADALALLQSNEGRW----GPSDPM 177

Query: 189 ------AQVYLWLEEAGWQIMGKTGVRVFHDYLREK-HQQRDCYEALLELETRYCRQEPY 241
                  Q+   + EAG ++    GVR+  D L  +  +     + LL +E         
Sbjct: 178 PRRYTAEQLTALVREAGLEVHELRGVRILGDLLPGRVFEDPQTPDTLLAVEKAASAHAEL 237

Query: 242 ITLGRYIHVTARKP 255
             +   +HV AR+P
Sbjct: 238 SRIATQLHVMARRP 251


>UniRef50_A3XJF1 Putative uncharacterized protein n=1 Tax=Leeuwenhoekiella
           blandensis MED217 RepID=A3XJF1_9FLAO
          Length = 249

 Score = 65.9 bits (159), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 50/175 (28%), Positives = 87/175 (49%), Gaps = 28/175 (16%)

Query: 37  VLAEMGPQK-LRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNM 95
           +++ + PQK  R+LD G G G+    +AE G Q++  D S +MID AK  A+ K    N+
Sbjct: 21  LISMLNPQKDERILDLGCGTGELTAAIAESGAQLVGIDASQEMIDAAK--AQFK----NI 74

Query: 96  QFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGL 155
           +FI    +      +   D I  +A L W+ +P + +  ++S L+ GG           L
Sbjct: 75  EFITARGESFID--QERYDAIFSNATLHWILNPEAAISAMYSNLKIGGR----------L 122

Query: 156 LMHNMVAGNFDYVQAGMPK--------KKKRTLSPDYPRDPAQVYLWLEEAGWQI 202
           L+    AGN D +   + +        K+ RT++  +P+     Y +LE++G+Q+
Sbjct: 123 LLEMGGAGNIDTIIKALSRVLEEKGYFKQSRTINWYFPKLGTYCY-FLEKSGFQV 176


>UniRef50_Q46F96 Ubiquinone/menaquinone biosynthesis methyltransferase n=2
           Tax=Methanosarcina RepID=Q46F96_METBF
          Length = 259

 Score = 63.9 bits (154), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 59/229 (25%), Positives = 101/229 (44%), Gaps = 24/229 (10%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
           + + D   KF     G   G + ++ +W  L  +   +GP    VLD G G G  A+ +A
Sbjct: 17  KKYWDYGSKFYDTAPGN--GGVEESQMWSKL--LSGAIGPGPKNVLDVGSGTGIIAMYLA 72

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
           E GH+V   D S  M+D A++ A  KG   N++F+    +++    ET  D I    VL 
Sbjct: 73  ELGHRVTAVDFSEGMMDVARKKALEKGA--NIRFMEMDVENLNFEDET-FDFITARYVLW 129

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLM--FYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLS 181
            ++ P   ++    V++PGG + ++   +   GLL        F+Y      K  K   +
Sbjct: 130 TMSHPEKAVKEWVRVVKPGGRIVIIDGKWVTKGLL---PCISAFNYHIYRFIKYGKNPFT 186

Query: 182 PDYPRD------------PAQVYLWLEEAGWQIMGKTGVRVFHDYLREK 218
            DY +D              QV  ++ +AG   +  T +++  D  R++
Sbjct: 187 YDYKKDINVSLPNPHGVESKQVVEYMSKAGLDDIAVTDLKIIRDIQRKR 235


>UniRef50_C2HDY5 S-adenosylmethionine-dependent methyltransferase n=12
           Tax=Enterococcus faecium RepID=C2HDY5_ENTFC
          Length = 200

 Score = 63.2 bits (152), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 55/185 (29%), Positives = 91/185 (49%), Gaps = 23/185 (12%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M    FD IA     N Y +   Q    I+ ++L   L     QK+ +LD GGG G  ++
Sbjct: 1   MTKNIFDSIA-----NHYDSPDRQALAKIIREELTTYLPRDSHQKV-LLDYGGGTGLVSL 54

Query: 61  KMAERGHQVILCDLSA---QMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPV---D 114
            +AER  ++I+ D S    +M++   QAA+ K    N++ IH  A      +E P    D
Sbjct: 55  PLAERFKELIIADASETMLKMVEEKIQAADLK----NVRTIHADAS-----VEFPAIQAD 105

Query: 115 LILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPK 174
           +IL   VL  + D +++L  L+ +L PGG L ++ ++ +  + H  V   F  +Q  +  
Sbjct: 106 VILLSLVLLHIPDTKTILMKLFELLAPGGQLIIVDFDKNEQISHPKVHNGF--IQEELND 163

Query: 175 KKKRT 179
           + K+T
Sbjct: 164 RLKKT 168


>UniRef50_C5CH90 Methyltransferase type 11 n=1 Tax=Kosmotoga olearia TBF 19.5.1
           RepID=C5CH90_KOSOT
          Length = 256

 Score = 62.4 bits (150), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 52/236 (22%), Positives = 107/236 (45%), Gaps = 15/236 (6%)

Query: 29  ILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEA 88
           +L+ ++ R L        ++LD G G G+ AI++A++G ++I  D + +M+  A++ A+ 
Sbjct: 25  VLYHEIVRKLINEHQVNGKILDLGTGTGRWAIELADKGMEIIAVDPAEKMLKVAEEKAKL 84

Query: 89  KGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLM 148
            GV  N++F   + + +     T   ++    VL +   P  VL+ +  VL+  G L   
Sbjct: 85  YGV--NIKFTKASGEALPFESNTFDFVLAMGDVLSYAKSPEKVLEEIKRVLKNRGKLLAT 142

Query: 149 FYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDY----------PRDPAQVYLWLEEA 198
             NA+  L H+ ++    Y      +++++    D           P  P  +   ++ A
Sbjct: 143 VDNAYAFL-HDFISQGETYNARRFIERERKVPIGDSSVSEKHFYTRPYFPEDIEKLVKNA 201

Query: 199 GWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPYITLGRYIHVTARK 254
             Q++    + VF  Y  EK  +    + +++ E  +CR++       ++   ARK
Sbjct: 202 SMQLIDIAALVVFAPYSEEKLARN--LDRIVQWELEFCRRKELFGRAEHLFFCARK 255


>UniRef50_B0SGJ1 Methylase/methyltransferase n=2 Tax=Leptospira biflexa serovar
           Patoc RepID=B0SGJ1_LEPBA
          Length = 199

 Score = 62.4 bits (150), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 51/168 (30%), Positives = 80/168 (47%), Gaps = 10/168 (5%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M+   FD IA ++        + QL + IL + L+ VL E+  + L  LD G G G   I
Sbjct: 1   MEPNVFDQIANQYDTE----ERIQLARHILAK-LEPVLLEISNKTL--LDFGCGTGLLGI 53

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
            +     +VIL D S  M+D      +AK + +       A  D+A     PVD IL   
Sbjct: 54  PLTSLYKEVILSDGSKVMLDVVDSKIKAKEIQNAKTI---APNDLAKSGALPVDHILMSL 110

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYV 168
           VL  + + + +L+T+ S L+PGG L L+ ++ +  + H  V   F  +
Sbjct: 111 VLLHIPNTKQILETIHSYLKPGGTLYLIDFDENKKVSHPKVHSGFKQI 158


>UniRef50_D1JD52 Putative uncharacterized protein n=1 Tax=uncultured archaeon
           RepID=D1JD52_9ARCH
          Length = 260

 Score = 62.4 bits (150), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 34/107 (31%), Positives = 66/107 (61%), Gaps = 3/107 (2%)

Query: 38  LAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQF 97
           L ++G + L++LD G G G  +I +AE GH+V+  D+S  M+ +A++ AE +G++ +++ 
Sbjct: 39  LEKLGKKPLKILDVGTGTGFLSISLAEIGHEVMGIDISEGMLSQARKKAEKRGLNFDLRI 98

Query: 98  IHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGV 144
               A+ ++   ET  D+++ +AVL  + +P   ++    VL+PGG 
Sbjct: 99  ED--AESLSLEDET-FDIVVSNAVLWSLPNPEKAVREWKRVLKPGGT 142


>UniRef50_Q3MEY9 Cyclopropane-fatty-acyl-phospholipid synthase n=5 Tax=Cyanobacteria
           RepID=Q3MEY9_ANAVT
          Length = 260

 Score = 62.0 bits (149), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 37/132 (28%), Positives = 69/132 (52%), Gaps = 11/132 (8%)

Query: 14  SRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLR-VLDAGGGEGQTAIKMAERGHQVILC 72
           ++N +  T  Q + + +WQ  + +L  + PQ    +LD G G GQ   K+A+ G +V+  
Sbjct: 7   AKNFWDATLYQDKHSFVWQYGEDLLQLLNPQPGEFILDLGCGTGQLTEKIAQSGAEVLGT 66

Query: 73  DLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASH-LETPVDLILFHAVLEWVADPRSV 131
           D +A MI++A+Q         N   +H    D  +  ++ P+D +  +A+L WV +P + 
Sbjct: 67  DNAATMIEKARQ---------NYPHLHFDVADARNFRVDKPLDAVFSNAMLHWVKEPEAA 117

Query: 132 LQTLWSVLRPGG 143
           + ++   L+ GG
Sbjct: 118 IASIHQALKSGG 129


>UniRef50_C9R8S5 Methyltransferase type 11 n=1 Tax=Ammonifex degensii KC4
           RepID=C9R8S5_AMMDK
          Length = 225

 Score = 61.6 bits (148), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 45/148 (30%), Positives = 76/148 (51%), Gaps = 12/148 (8%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           FD  A  +  + Y T +G+L   + W+ L ++L+    +K  VLDAG G G  +  +A  
Sbjct: 4   FDAYATHYE-DWYATPRGRLVWELEWRCLQKLLSLRPGEK--VLDAGCGTGVVSRALAAA 60

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVAS--HLETPVDLILFHAVLE 123
           G +V   D+S  M+  A++    KG   N+ ++     D++S    +   D ++    LE
Sbjct: 61  GAEVTGIDISPAMLAVARE----KGAGGNIVYLE---GDMSSLPFPDASFDAVVCFTALE 113

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYN 151
           +VA+P   L+ +W VL+PGG L +   N
Sbjct: 114 FVAEPERALEEMWRVLKPGGRLLVGVLN 141


>UniRef50_A4X9U1 Methyltransferase type 11 n=5 Tax=Actinomycetales
           RepID=A4X9U1_SALTO
          Length = 256

 Score = 61.6 bits (148), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 50/155 (32%), Positives = 76/155 (49%), Gaps = 8/155 (5%)

Query: 21  TKGQL-------RQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCD 73
           T+G+L       R A++W  L   L       L VLD GGG G  A+ +A+ GH+V + D
Sbjct: 11  TRGRLAGPPLTPRTAVIWSVLRAELDRRADTDLTVLDVGGGTGGFAVPLAQAGHRVTVVD 70

Query: 74  LSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLE-TPVDLILFHAVLEWVADPRSVL 132
            +   +    + A   GV+D ++ +      +A  +E   VDL+L HAVLE V DP +V+
Sbjct: 71  ANPDALAALTRRAADAGVADRVRAVQGDGDALAGLVEPASVDLVLCHAVLEVVDDPVAVV 130

Query: 133 QTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDY 167
             L   LRPGG  S++       ++   + G  D 
Sbjct: 131 AALAGALRPGGAASVLVAGRAAAVLSRAMTGQLDV 165


>UniRef50_D0RTX5 S-adenosylmethionine-dependent methyltransferase n=4
           Tax=Streptococcus RepID=D0RTX5_9STRE
          Length = 234

 Score = 61.2 bits (147), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 58/235 (24%), Positives = 106/235 (45%), Gaps = 29/235 (12%)

Query: 23  GQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRA 82
           G++   IL+  L  V      + ++VLD G G G  A  +AE+ +QV   + + +MI   
Sbjct: 15  GKIYYDILFDQLKNV------EGMKVLDFGSGFGIVANHLAEK-NQVTALEPNMEMIIHR 67

Query: 83  KQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPG 142
           K+    + +  +++ +     +         DLI+ H VLE++ D    L     +L+ G
Sbjct: 68  KRTNSYEQLQGSLEVLEIFKDE-------SFDLIICHNVLEYIEDIDPYLMAFSRLLKKG 120

Query: 143 GVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAG--- 199
           G LS++ +N  G +MH ++  N       + K ++  L  DY        ++ E A    
Sbjct: 121 GKLSIVKHNYVGRIMHTVIFEN------DIKKARELLLGKDYLTHSMGQAVYYEIADVIK 174

Query: 200 ---WQIMGKTGVRVFHDYLREKHQQRD--CYEALLELETRYCRQEPYITLGRYIH 249
              ++I+   G+R+F+  L+    + D    E +LE+E     Q PY  +  + H
Sbjct: 175 PYPFEILDFQGIRIFYG-LQPNDVKTDPGWRENMLEMELSVNNQSPYRDIAAFQH 228


>UniRef50_Q482G8 3-demethylubiquinone-9 3-methyltransferase n=27
           Tax=Gammaproteobacteria RepID=UBIG_COLP3
          Length = 246

 Score = 60.5 bits (145), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 51/186 (27%), Positives = 91/186 (48%), Gaps = 24/186 (12%)

Query: 46  LRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDV 105
           ++++D G G G  +  +A+ G  V   D+  + ++ AK  A   GVS N Q I   A++ 
Sbjct: 64  MQIIDVGCGGGILSESLAKLGANVTGIDMGTEPLNVAKLHALETGVSINYQKI--TAEEK 121

Query: 106 ASHLETP--VDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAG 163
           A  LE P   D++    +LE V DP SV+Q   ++++PGG   L+F++     + +    
Sbjct: 122 A--LENPGTFDVVTCMEMLEHVPDPASVIQACSTLVKPGG---LIFFSTLNKSIKS---- 172

Query: 164 NFDYVQAGMPKKKKRTLSPDYPRD------PAQVYLWLEEAGWQIMGKTGVRVFHDYLRE 217
              Y+ A +  +K   + PD   D      P+Q+  W EE G + +  +G+   ++ +  
Sbjct: 173 ---YLLAILAAEKLLKIVPDGTHDHDKFIRPSQLIGWAEEHGLKCIDASGIH--YNPITG 227

Query: 218 KHQQRD 223
            H+  D
Sbjct: 228 NHKLND 233


>UniRef50_B5WCF5 Methyltransferase type 11 n=1 Tax=Burkholderia sp. H160
           RepID=B5WCF5_9BURK
          Length = 305

 Score = 60.5 bits (145), Expect = 6e-08,   Method: Compositional matrix adjust.
 Identities = 34/118 (28%), Positives = 65/118 (55%), Gaps = 6/118 (5%)

Query: 35  DRVL--AEMGPQKLRVLDAGGGEGQTAIKMAERGH---QVILCDLSAQMIDRAKQAAEAK 89
           DRVL   ++ P  + + D G G+G    +  ERG    +V++ D+SA ++   ++ A   
Sbjct: 41  DRVLDFIDLRP-GMTLADIGTGDGLVGFRAIERGGVSIRVVMTDISAPLLRHTQETARTL 99

Query: 90  GVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSL 147
           GVS+   ++ C+A+++    +  VD     AVL +V D  + ++ L+ +L+PGG  ++
Sbjct: 100 GVSEQCAYLQCSAENLDGIADEAVDAATMRAVLAYVEDKPAAMRELYRILKPGGRFAI 157


>UniRef50_D0MGM2 Methyltransferase type 11 n=3 Tax=root RepID=D0MGM2_RHOM4
          Length = 274

 Score = 60.1 bits (144), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 41/104 (39%), Positives = 59/104 (56%), Gaps = 8/104 (7%)

Query: 44  QKLRVLDAGGGEGQTAIKMAER--GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCA 101
           + +RVLDAG G GQ A  +A R    +V+  DL    +++A++      V+  ++F    
Sbjct: 53  RPVRVLDAGTGFGQYAYYIARRYPRAEVVGVDLKTDYLEQARRFVARTPVAGRVRF---- 108

Query: 102 AQDVASHLET--PVDLILFHAVLEWVADPRSVLQTLWSVLRPGG 143
           AQD  + L+T  P DLIL   VLE + D R+VL+    VLRPGG
Sbjct: 109 AQDDLTRLQTEGPFDLILSVDVLEHIEDDRAVLRNFARVLRPGG 152


>UniRef50_Q1QEI9 3-demethylubiquinone-9 3-methyltransferase n=59 Tax=Proteobacteria
           RepID=UBIG_PSYCK
          Length = 257

 Score = 60.1 bits (144), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 36/113 (31%), Positives = 55/113 (48%)

Query: 39  AEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFI 98
           AEMG    +VLD G G G  +  MA RG  V   DL  + +  A   AE   + D +++ 
Sbjct: 64  AEMGLAGKKVLDVGCGGGILSESMARRGADVTGIDLGTENLKAASLHAEQSNLQDTLRYQ 123

Query: 99  HCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYN 151
           H   + +A+      D++    +LE V DP +++   + +L PGGV  L   N
Sbjct: 124 HIPVEALAATHAGQFDVVTCMEMLEHVPDPAAIVDACFKLLAPGGVCVLSTIN 176


>UniRef50_Q8TYX8 SAM-dependent methyltransferase n=1 Tax=Methanopyrus kandleri
           RepID=Q8TYX8_METKA
          Length = 182

 Score = 60.1 bits (144), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 33/96 (34%), Positives = 57/96 (59%), Gaps = 1/96 (1%)

Query: 48  VLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVAS 107
           V+DAG G G  AI  AE G +V+  D+  +MID A++ AE  GV D+++F+   A+++  
Sbjct: 43  VVDAGTGNGVVAIAAAEMGCEVLAVDVDPEMIDMARRNAEEYGVEDSIEFVVADARELPE 102

Query: 108 HLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGG 143
            ++  VD +L    ++ V +P   L++  +VL+  G
Sbjct: 103 LVDN-VDAVLSTVPVKTVPEPLEFLRSCATVLKTSG 137


>UniRef50_C9LQ45 SmtA protein n=2 Tax=Clostridiales RepID=C9LQ45_9FIRM
          Length = 249

 Score = 60.1 bits (144), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 35/102 (34%), Positives = 54/102 (52%), Gaps = 3/102 (2%)

Query: 44  QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQ 103
           +KL +LD G G G   + + E+GH V   D++  MI RA +   A GV  ++  + C  Q
Sbjct: 45  EKLEILDVGTGPGFFPVLLGEKGHHVTGIDITENMIRRAAENISAAGVKADLAVMDC--Q 102

Query: 104 DVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVL 145
           ++  H E+  DL++   +   +ADP    +    VLR GGVL
Sbjct: 103 NIQYHDES-FDLVVCRDLTWTLADPVKAYKEWTRVLRKGGVL 143


>UniRef50_A4FIY5 Ubiquinone/menaquinone biosynthesis methyltransferase n=1
           Tax=Saccharopolyspora erythraea NRRL 2338
           RepID=A4FIY5_SACEN
          Length = 245

 Score = 59.7 bits (143), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 48/145 (33%), Positives = 66/145 (45%), Gaps = 8/145 (5%)

Query: 4   RNFDDIA---EKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           RN+D  A    +F R      +   R A   + +   L   G   L VLD G G G  + 
Sbjct: 13  RNWDRRARDYNRFYRRFSADRRDAWRTAC--EKIVPALRPGGAGPLDVLDVGTGTGFLST 70

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
            +AE GH+V   D SA M+  A++ AE +GV  ++ F  C A DV   L +  DL+    
Sbjct: 71  LLAELGHRVTAVDPSATMLGYAREEAERRGV--DVSFRECGAHDV-EDLASTFDLVTARY 127

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVL 145
           VL  +  P         VLRPGG +
Sbjct: 128 VLWTLPAPVRATAAWSRVLRPGGAV 152


>UniRef50_UPI0001AF209D methyltransferase type 11 n=1 Tax=Streptomyces ghanaensis ATCC
           14672 RepID=UPI0001AF209D
          Length = 277

 Score = 58.9 bits (141), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 66/226 (29%), Positives = 96/226 (42%), Gaps = 31/226 (13%)

Query: 47  RVLDAGGGEGQTAIKMAER-GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDV 105
           RVLDAG G G  A+ +AE  G  V    +S        Q A A+G+SD ++F H    ++
Sbjct: 66  RVLDAGCGPGGPALLVAEETGADVTGVTVSRFEAGAGTQKASARGLSDRVRFEHGDYAEL 125

Query: 106 ASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNF 165
             H +   D ++    L++  D    L  L+ VLRPGG L++  Y     L   +     
Sbjct: 126 GHHADGSFDAVMAMESLQYAPDLPRALAELFRVLRPGGALTMTDYT----LAARVPPAER 181

Query: 166 DYVQAGMPKKKKRTLSPDYPRDPAQVYLWLE---EAGWQIMGKT--GVRVF---HDYLRE 217
           D +       +K TL    P     V  WLE   EAG+++   T  G RVF     Y+  
Sbjct: 182 DEL------AEKLTLPHLQP-----VEGWLEVLREAGFRVEEYTQCGPRVFGLGAKYVEA 230

Query: 218 KHQQRDCYEALLELETRYCRQEP---YITLG----RYIHVTARKPQ 256
             + RD   A    E     +E    + + G     Y  VT R+P+
Sbjct: 231 AEEGRDALRAAFGEEAVAGLKEAMADFFSPGAERIEYSIVTVRRPR 276


>UniRef50_D1CAG8 Methyltransferase type 11 n=1 Tax=Sphaerobacter thermophilus DSM
           20745 RepID=D1CAG8_SPHTD
          Length = 286

 Score = 58.9 bits (141), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 54/172 (31%), Positives = 81/172 (47%), Gaps = 25/172 (14%)

Query: 21  TKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMID 80
           T G+L +A +W+ LD   A   P   RVLD G G G+ A+++A+RG  V+  D+SA MI 
Sbjct: 23  TLGRLLRAAVWEHLD---AAFHPGD-RVLDLGCGTGEDAVRLAQRGIDVLATDVSAGMIA 78

Query: 81  RAKQAAEAKGVSDNMQFIHCAAQDVASH-LETPVDL---------ILFHAVLEWVADPRS 130
            A++ A   GV++    +H A  D+  H L  P                  L  + D R 
Sbjct: 79  VAREKAADAGVAER---VHLAQVDLREHPLSLPASWRGPDGIDGSFSSFGALNCLPDRRR 135

Query: 131 VLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQA-GMPKKKKRTLS 181
           +  TL + +RPGG L L+       LM  +      +  A G P++  R L+
Sbjct: 136 LASTLAAWIRPGGRLVLV-------LMGPLCPWEIGWHMARGQPRRAVRRLT 180


>UniRef50_A7NNU9 MCP methyltransferase, CheR-type n=1 Tax=Roseiflexus castenholzii
           DSM 13941 RepID=A7NNU9_ROSCS
          Length = 297

 Score = 58.9 bits (141), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 32/103 (31%), Positives = 55/103 (53%), Gaps = 2/103 (1%)

Query: 48  VLDAGGGEGQTAIKMAERGHQ--VILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDV 105
           VLD G G+G  A    ER     +I  D+S  +++ A+  A   G+ D  QF+   A+D+
Sbjct: 48  VLDVGCGDGLIAFGALERSASGTIIFSDISQDLLNHARSLAREMGLLDRCQFLLAPAEDL 107

Query: 106 ASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLM 148
           +   +  VD++   +VL +V+  +   +  + VL+PGG LS+ 
Sbjct: 108 SVLEDASVDVVTTRSVLIYVSAKQQAFREFYRVLKPGGRLSIF 150


>UniRef50_Q65GZ7 Putative uncharacterized protein n=1 Tax=Bacillus licheniformis
           ATCC 14580 RepID=Q65GZ7_BACLD
          Length = 198

 Score = 58.2 bits (139), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 32/126 (25%), Positives = 61/126 (48%), Gaps = 3/126 (2%)

Query: 42  GPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCA 101
             Q   ++D G G G  ++++++  H ++L D S QM++ AK     KG+++        
Sbjct: 35  NSQSKSLIDYGSGTGLISLELSDLVHSILLVDSSKQMLEVAKAKISRKGIANAKTLYSDF 94

Query: 102 AQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMV 161
            Q+     E   D++L   VL  + D   +LQ L+ +L  GG L ++ ++ +  + H  V
Sbjct: 95  TQETP---ELKADIVLMSLVLLHIPDTNKILQELFGILNDGGKLIIIDFDKNDKIQHPKV 151

Query: 162 AGNFDY 167
              F +
Sbjct: 152 HNGFSH 157


>UniRef50_D1Z1A4 Putative uncharacterized protein n=1 Tax=Methanocella paludicola
           SANAE RepID=D1Z1A4_METPS
          Length = 267

 Score = 57.8 bits (138), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 31/98 (31%), Positives = 54/98 (55%), Gaps = 1/98 (1%)

Query: 48  VLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVAS 107
           VLD G G G+T+  +A  G +V+  D+  +MI  +K  A   GVSD   F+ C A+ +  
Sbjct: 49  VLDVGCGMGKTSCMLAGMGCRVVGVDIMPRMIKESKARAWQTGVSDKTTFVECDARSLPF 108

Query: 108 HLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVL 145
             ET  D ++  +V  ++ D    ++  + V++PGG++
Sbjct: 109 EPET-FDAVVVESVTVFMDDVERAIKGYYRVVKPGGIV 145


>UniRef50_B0U3W1 3-demethylubiquinone-9 3-methyltransferase n=7 Tax=Xylella
           fastidiosa RepID=UBIG_XYLFM
          Length = 246

 Score = 57.8 bits (138), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 48/176 (27%), Positives = 80/176 (45%), Gaps = 6/176 (3%)

Query: 34  LDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSD 93
           LD +   +     RVLD G G G  +  +A +G  V   DL+ ++I  A+      G+  
Sbjct: 45  LDYISKRVSLSGARVLDVGCGGGLLSEALARQGAHVTAIDLAPELIKAARLHGLESGIQV 104

Query: 94  NMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAH 153
           + +    A +D+ +    P D I    +LE V DP +++     +L+PGG L +   N  
Sbjct: 105 DYRIQ--AIEDLLAEQPAPFDAIACMEMLEHVPDPAAIVDACAHLLKPGGRLFVSTIN-R 161

Query: 154 GLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVR 209
            L    +     +YV   +PK   +    D+ R PA++  WL  AG  +   +G+R
Sbjct: 162 TLAAFMLAVVGAEYVVRLLPKGTHQY--KDFIR-PAELAAWLRHAGLHLEDVSGMR 214


>UniRef50_D2M284 Methyltransferase type 11 n=1 Tax=Bacillus cellulosilyticus DSM
           2522 RepID=D2M284_BACS4
          Length = 250

 Score = 57.8 bits (138), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 49/181 (27%), Positives = 84/181 (46%), Gaps = 15/181 (8%)

Query: 18  YGTTKGQLRQAILWQDLDRVLAEMGPQK-LRVLDAGGGEGQTAIKMAERGHQVILCDLSA 76
           YG TKG  ++      +D ++ E+  QK  RVLD G G G+  +++A RG++    D+S+
Sbjct: 31  YGFTKGTTKE------VDFLIEELNLQKQSRVLDVGCGPGRHTLELARRGYRAFGIDISS 84

Query: 77  QMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADP---RSVLQ 133
           + I  A++ A  + +  +  F+   A+++    E    + L         +    R VL+
Sbjct: 85  EFIKLAEEKAAGEKLPAD--FMKMDARNLTFKNEFDAAICLCEGAFGLAGNEHNHRQVLK 142

Query: 134 TLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYL 193
           +++  LRPG +  L   NA GL+        FD     +  K+  T S     D  QV L
Sbjct: 143 SVYHALRPGSLFVLTAINALGLVKRITNETQFDPYSCTVVDKEIITNSNG---DTKQVSL 199

Query: 194 W 194
           +
Sbjct: 200 Y 200


>UniRef50_B9K8U5 Ubiquinone/menaquinone biosynthesis methyltransferase-related
           protein n=6 Tax=Thermotogaceae RepID=B9K8U5_THENN
          Length = 258

 Score = 57.8 bits (138), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 57/246 (23%), Positives = 108/246 (43%), Gaps = 22/246 (8%)

Query: 16  NIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLS 75
           ++Y T K +L   ++       L+E      RVLD GGG G+ ++ + ERG  V L D S
Sbjct: 18  SMYETPKWRLYHRLI----QSFLSEHLKVPCRVLDLGGGTGRWSLFLLERGFDVTLVDPS 73

Query: 76  AQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTL 135
            +M+    + AE KGV    +F+   A+D+     +   ++    VL +V +       +
Sbjct: 74  EEML----KIAEKKGVK---KFLKARAEDLPFSSHSFDTVLAMGDVLSYVENKVKAFSEI 126

Query: 136 WSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWL 195
             VL+PGG+L     N +  L H +    ++ +   +   K +T+           Y + 
Sbjct: 127 ARVLKPGGLLIATVDNFYTFLQHMIEENTWEKIPRFL---KTQTIEVGNTLFSFNSYAFR 183

Query: 196 EE-----AGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPYITLGRYIHV 250
            E      G+  +   G+ VF DY  ++ ++++  + + ELE  + R    +    ++  
Sbjct: 184 PEDIESIEGFDTIEVRGIGVF-DYSEDQVRKKE--DLIFELEKEFSRDRAILWRAEHVFF 240

Query: 251 TARKPQ 256
             +K +
Sbjct: 241 VLKKKE 246


>UniRef50_C7I3S4 Methyltransferase type 11 n=1 Tax=Thiomonas intermedia K12
           RepID=C7I3S4_THIIN
          Length = 229

 Score = 57.4 bits (137), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 40/120 (33%), Positives = 61/120 (50%), Gaps = 9/120 (7%)

Query: 34  LDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSD 93
           L R  A   P   R+L A  GEG+ +I +AE+GH V   DLS   +D+A++ ++ +GVS 
Sbjct: 53  LVRESARFAPAS-RILSAADGEGRNSIWLAEQGHHVTAFDLSPVAVDKARRWSQERGVSV 111

Query: 94  NMQFIHCAAQDVASHLETPVDLILFHAVLEWVADP---RSVLQTLWSVLRPGGVLSLMFY 150
           +    H A+ D         D ++  A+    ADP     +   LW  L+PGG+L +  Y
Sbjct: 112 DF---HVASVDEWDWAPGRFDAVV--AIFVQFADPALRERLFSGLWRTLKPGGLLCVQGY 166


>UniRef50_Q8TIA7 Phosphatidylethanolamine N-methyltransferase n=3 Tax=Methanosarcina
           RepID=Q8TIA7_METAC
          Length = 252

 Score = 57.4 bits (137), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 38/119 (31%), Positives = 62/119 (52%), Gaps = 8/119 (6%)

Query: 27  QAILWQDLDRVLAEMGP--QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQ 84
           + I+W+   R+L    P  Q+L+VLD G G G  A+  AE GH+V   D+S  M+++A+ 
Sbjct: 29  ERIIWR---RMLENFLPPGQRLKVLDVGTGPGFLALLFAEMGHEVTAVDISMGMLEKARN 85

Query: 85  AAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGG 143
            A+  GV   +   H  A+ +    +   DL++   +L  +  P   +Q    VL+PGG
Sbjct: 86  NAKTLGVK--VDLFHGDAEKLPFE-DCYFDLVVNKYLLWTLPQPEIAVQEWMRVLKPGG 141


>UniRef50_D1JD78 Putative uncharacterized protein n=1 Tax=uncultured archaeon
           RepID=D1JD78_9ARCH
          Length = 256

 Score = 57.4 bits (137), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 40/135 (29%), Positives = 68/135 (50%), Gaps = 7/135 (5%)

Query: 16  NIYGTTKG--QLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCD 73
           N YG  +G     + I W D+  + + +G ++  VLD G G G  AI +AE  H V   D
Sbjct: 24  NDYGKFRGYGSEEEKIAWMDV--LSSALGTERRNVLDVGTGPGDIAIYLAEMEHDVTGID 81

Query: 74  LSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQ 133
            S +M+ RAK     K  +  ++F  C A+D+    E+  D ++   +L  + +P   L+
Sbjct: 82  FSDEMLKRAK--GRVKNSNLQVKFDICDAEDLYFEDES-FDAVICRHLLWTLPNPGKALR 138

Query: 134 TLWSVLRPGGVLSLM 148
               V++PGG + ++
Sbjct: 139 EWTRVVKPGGKIVVI 153


>UniRef50_C7MUF7 Methylase involved in ubiquinone/menaquinone biosynthesis n=6
           Tax=Actinomycetales RepID=C7MUF7_SACVD
          Length = 244

 Score = 57.4 bits (137), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 48/159 (30%), Positives = 82/159 (51%), Gaps = 12/159 (7%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTA---IKM 62
           FDD A  + R + G   G    A L    +R+        LR+LDAG G G +    + +
Sbjct: 18  FDDGARSYDR-LVGLNPGY--HAHLRLSAERLRLPGDGAGLRLLDAGCGTGASTAALLAV 74

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
           A R  +++  D SA+M+  A++    K   D+++F+H + +++A  +  P D IL   ++
Sbjct: 75  APRA-EIVAIDASARMLAEARR----KPWPDSVRFVHTSVEELAG-VSGPFDGILAAYLV 128

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMV 161
             +ADP + L+ L  +LRPG  L++  Y+    +M  MV
Sbjct: 129 RNLADPDAQLRALARLLRPGATLAVHEYSVRDSVMATMV 167


>UniRef50_C1RH88 Methylase involved in ubiquinone/menaquinone biosynthesis n=2
           Tax=Cellulomonas flavigena DSM 20109 RepID=C1RH88_9CELL
          Length = 457

 Score = 57.4 bits (137), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 37/111 (33%), Positives = 56/111 (50%), Gaps = 9/111 (8%)

Query: 48  VLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVAS 107
           VLD GGG G  A  +A+ G+ V++ D S  M+        A   S  ++     A D+  
Sbjct: 48  VLDVGGGTGNYAAALADAGYDVLVLDRSPDML--------AVAASKGLRTRRADATDLPV 99

Query: 108 HLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMH 158
             +  VD++   AVL  + D R+ L+    VLRPGGVL+L+ Y +  +  H
Sbjct: 100 A-DASVDVVTMVAVLHQIPDWRAALREARRVLRPGGVLALVLYTSEHMASH 149


>UniRef50_D1C6B8 Methyltransferase type 11 n=2 Tax=Thermomicrobia (class)
           RepID=D1C6B8_SPHTD
          Length = 208

 Score = 57.4 bits (137), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 39/105 (37%), Positives = 60/105 (57%), Gaps = 5/105 (4%)

Query: 46  LRVLDAGGGEGQTAIKMAER---GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAA 102
           +RVLDAG G G+  I  A R     +V+  D+  +M+ + +Q A A+GV+ N++ +  A 
Sbjct: 62  MRVLDAGAGTGRLTIPAARRVAPNGEVVALDIQPEMLAKLEQRAAAEGVT-NIRTVQAAL 120

Query: 103 QDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSL 147
            D A   E+  D  L  AVL    D  +VL+ L + L+PGG+LS+
Sbjct: 121 GDGALEPES-FDRALLVAVLGETPDQLAVLRDLHAALKPGGILSV 164


>UniRef50_A8FSR8 Methylase involved in ubiquinone/menaquinone biosynthesis-like
           protein n=2 Tax=Shewanella RepID=A8FSR8_SHESH
          Length = 402

 Score = 57.0 bits (136), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 42/146 (28%), Positives = 75/146 (51%), Gaps = 14/146 (9%)

Query: 46  LRVLDAGGGEGQTAIKMAERGHQVILC--DLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQ 103
           L+VLDAG G G   +  A     V+    D+++  +  A+  A+A+G++ N+ F+     
Sbjct: 47  LQVLDAGCGRGPGVLGAASLQPNVMFTAIDINSVGLAEARANAQARGLT-NINFVQADLM 105

Query: 104 DVASHLETP---VDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHG------ 154
            +   +E P    D+I    VL  +ADP+  L  L S+L P GV+SLM Y ++G      
Sbjct: 106 TLEG-VEVPPGGFDVIYSSGVLHHLADPQMGLNNLTSILAPHGVISLMLYGSYGRQALYR 164

Query: 155 -LLMHNMVAGNFDYVQAGMPKKKKRT 179
            +   ++++ N D +++ +P  +  T
Sbjct: 165 LIEGIDILSSNEDAIESRLPLARALT 190


>UniRef50_B9XNM3 Methyltransferase type 11 n=2 Tax=Verrucomicrobia
           RepID=B9XNM3_9BACT
          Length = 259

 Score = 57.0 bits (136), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 40/139 (28%), Positives = 70/139 (50%), Gaps = 6/139 (4%)

Query: 11  EKFSRNIYGTTKGQLRQAILWQDLDRVLAEMG-PQKLRVLDAGGGEGQTAIKMAERGHQV 69
           E+F+R  +   +G + + +  +D+   L  +  P K +VLD   G G T + +A  GH+V
Sbjct: 12  EQFARQSHRYGQGHILEQV--EDVRSALESVNLPVKAKVLDVATGGGHTGLLLASLGHEV 69

Query: 70  ILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPR 129
           +L D++  M+DRA + A  +G S + +  H A Q    + E   DL+         + P 
Sbjct: 70  MLADIAQPMLDRAARTALERGFSVSTK-QHAAEQ--LPYPEEEFDLVTCRVAAHHFSSPE 126

Query: 130 SVLQTLWSVLRPGGVLSLM 148
           + ++    VL+P G L L+
Sbjct: 127 NFIRETARVLKPKGYLLLI 145


>UniRef50_Q02BK2 Methyltransferase type 12 n=1 Tax=Candidatus Solibacter usitatus
           Ellin6076 RepID=Q02BK2_SOLUE
          Length = 281

 Score = 56.6 bits (135), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 32/106 (30%), Positives = 53/106 (50%), Gaps = 1/106 (0%)

Query: 47  RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA 106
           +VL+ G G G   I  A  G QV   DL+ + ++ A+Q A+  G+ D ++FI   A+ ++
Sbjct: 66  KVLEIGCGIGTDTINFARHGAQVTAVDLTEKSLEVARQRAKVFGLEDRIRFIQANAEKLS 125

Query: 107 SHLETP-VDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYN 151
             +     DLI    V+     P +VL+ L   + P   + +M YN
Sbjct: 126 ESVPLEQYDLIYSFGVIHHTPHPENVLEQLRKYVSPQSTVKIMVYN 171


>UniRef50_C1D1R7 Putative Trans-aconitate 2-methyltransferase n=1 Tax=Deinococcus
           deserti VCD115 RepID=C1D1R7_DEIDV
          Length = 261

 Score = 56.6 bits (135), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 35/118 (29%), Positives = 61/118 (51%), Gaps = 11/118 (9%)

Query: 47  RVLDAGGGEGQTAIKMAERGHQ--VILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQD 104
           +++D G G G+  + +A R  Q  V+  D S +M+ RA         + N+ F     +D
Sbjct: 33  QIVDLGCGTGEQTLTLARRFPQARVLGLDSSPEMLSRAPVQQ-----APNLSFAQGDIRD 87

Query: 105 VASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVA 162
           +  H     DLI  +A L+W+ D  ++L  LW++L+PGGVL++     H    H +++
Sbjct: 88  LGGH----YDLIYSNAALQWLPDHEALLPALWTLLQPGGVLAVQIPANHEHPSHRLLS 141


>UniRef50_Q2FPU4 UbiE/COQ5 methyltransferase n=1 Tax=Methanospirillum hungatei JF-1
           RepID=Q2FPU4_METHJ
          Length = 250

 Score = 56.2 bits (134), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 36/108 (33%), Positives = 56/108 (51%), Gaps = 3/108 (2%)

Query: 41  MGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHC 100
           +G   L++LD G G G  +I +A  GH V   DLS  M+D A++ A A  V   + F   
Sbjct: 41  LGTAPLKILDVGTGPGSISIPLASMGHMVTAVDLSDNMLDLARKNAVASNVI--VDFRKG 98

Query: 101 AAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLM 148
            A+++     T  D ++   VL  V DP S L+    V++PGG + ++
Sbjct: 99  DAENLPFDDNT-FDAVVNRWVLWTVPDPTSALREWTRVVKPGGRVCII 145


>UniRef50_B0TYT6 S-adenosylmethionine (SAM)-dependent methyltransferase n=2
           Tax=Francisella philomiragia RepID=B0TYT6_FRAP2
          Length = 253

 Score = 56.2 bits (134), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 31/114 (27%), Positives = 58/114 (50%), Gaps = 7/114 (6%)

Query: 35  DRVLAEMGPQK-LRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSD 93
           + ++  + PQK  ++LD G G G+   K+  +G  ++  D+S QM+++AK+         
Sbjct: 24  NEIVELLSPQKDEKILDIGCGTGELTNKIKLQGASIVGIDVSNQMLNQAKKNYP------ 77

Query: 94  NMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSL 147
           N+QFI   AQ          D +  +A L W+ +P +V++ +  +L+  G   L
Sbjct: 78  NIQFIEADAQQDLPFNSEDFDAVFSNAALHWMLNPTAVIKNINKILKKNGRFVL 131


>UniRef50_Q123Z0 Methyltransferase type 12 n=2 Tax=Polaromonas RepID=Q123Z0_POLSJ
          Length = 441

 Score = 56.2 bits (134), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 38/113 (33%), Positives = 57/113 (50%), Gaps = 5/113 (4%)

Query: 46  LRVLDAGGGEGQTAIKMAER----GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCA 101
            R L AGGG G   I +AE+      Q++  D+S   I  AK+ A  +G+S N+ ++H +
Sbjct: 56  FRALVAGGGTGDATIFLAEQLRATDAQIVHLDMSEASIALAKERARIRGLS-NITWVHDS 114

Query: 102 AQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHG 154
             ++      P D I    VL  +ADP    + L +VL+P G + LM Y   G
Sbjct: 115 LLNLPHLGLAPFDYINCSGVLHHLADPDLGFRALRAVLKPEGAIGLMVYATAG 167


>UniRef50_A3CRX6 Glycosyl transferase, family 2 n=1 Tax=Methanoculleus marisnigri
           JR1 RepID=A3CRX6_METMJ
          Length = 996

 Score = 56.2 bits (134), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 39/138 (28%), Positives = 70/138 (50%), Gaps = 8/138 (5%)

Query: 37  VLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQ 96
           +L E+  +   VL+ G   G  +  + ERG+ V   ++  +  + A Q  ++  V D  +
Sbjct: 29  LLIELTGRNKDVLEVGTSTGYVSRVLKERGNTVTGIEIDPEAGEIAGQHCDSMIVGDIEK 88

Query: 97  FIHCAAQDVASHL-ETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYN-AHG 154
                  D+ ++L  +  D+I+F  VLE +A P  VL+ +   LRP G L++   N  HG
Sbjct: 89  L------DLDAYLAPSSFDVIIFGDVLEHLASPEDVLRKVKKYLRPDGYLAVSLPNVCHG 142

Query: 155 LLMHNMVAGNFDYVQAGM 172
            ++ N++ G+F Y   G+
Sbjct: 143 DVILNLLMGDFKYTSMGL 160


>UniRef50_C5RP33 Methyltransferase type 11 n=1 Tax=Clostridium cellulovorans 743B
           RepID=C5RP33_CLOCL
          Length = 260

 Score = 56.2 bits (134), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 44/149 (29%), Positives = 78/149 (52%), Gaps = 12/149 (8%)

Query: 8   DIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAE-MGPQKLRVLDAGGGEGQTAIKMAERG 66
           ++ E +  NIY   +   R  + +    R L + +  + L V D GGG G+ +  +AE+G
Sbjct: 2   NVIENYYDNIYDEWERLERHKLEFDITKRYLDKYIIGESLEVFDIGGGPGRYSFYLAEKG 61

Query: 67  HQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLI-----LFHAV 121
           H+V L DLS++ I+ AK+ A+   V    ++I+  A ++  + E   D+I     L+H V
Sbjct: 62  HKVSLLDLSSRNIEVAKEKAKEFNVGLK-EYIYGNALELEKY-EQKYDVILLMGPLYHLV 119

Query: 122 LEWVADPRSV-LQTLWSVLRPGGVLSLMF 149
            E   D R + ++    +L+PGG++   F
Sbjct: 120 KE---DQRKLAVEGALRLLKPGGIIFATF 145


>UniRef50_Q01S22 Methyltransferase type 11 n=1 Tax=Candidatus Solibacter usitatus
           Ellin6076 RepID=Q01S22_SOLUE
          Length = 243

 Score = 55.8 bits (133), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 45/138 (32%), Positives = 69/138 (50%), Gaps = 12/138 (8%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           FD +A ++      T  G+ ++ ++W+D++ +  E G    R+LD G G G+ A   A R
Sbjct: 7   FDGMAARYDAMWTTTPVGRAQRDLVWRDVEPLF-EAGE---RILDIGCGTGEDAAHFAAR 62

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV 125
           G  V   D S  M+     AA A+GV+  +    C A+DVA   ET    I     L  V
Sbjct: 63  GVAVRAIDASPAMV----SAARARGVAAEV----CRAEDVARIEETFDGAISNFGALNCV 114

Query: 126 ADPRSVLQTLWSVLRPGG 143
            D  +V ++L +V+ PGG
Sbjct: 115 EDLSAVAESLAAVVHPGG 132


>UniRef50_A9KJQ3 Methyltransferase type 11 n=1 Tax=Clostridium phytofermentans ISDg
           RepID=A9KJQ3_CLOPH
          Length = 312

 Score = 55.8 bits (133), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 26/69 (37%), Positives = 42/69 (60%)

Query: 49  LDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASH 108
            DAG G G+ +I +A++G  V   D+S  MID+AK+ A   GVSD + F+  A +D+  +
Sbjct: 53  FDAGAGSGRFSILLAKQGIHVTHFDISQPMIDKAKELAAEAGVSDKINFVKRALEDLTDY 112

Query: 109 LETPVDLIL 117
            +   DL++
Sbjct: 113 SDNSFDLVM 121


>UniRef50_Q2SLT2 SAM-dependent methyltransferase n=1 Tax=Hahella chejuensis KCTC
           2396 RepID=Q2SLT2_HAHCH
          Length = 370

 Score = 55.5 bits (132), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 39/114 (34%), Positives = 64/114 (56%), Gaps = 6/114 (5%)

Query: 42  GPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCA 101
           G +  R+L+ G GEG     +++    VI  D S +M+ +A+  A+A+ +S N++FI   
Sbjct: 178 GEKVNRLLEIGPGEGAFLEDLSQMADSVIALDNSEEMLQKARDFADARQLS-NVRFI--- 233

Query: 102 AQDVASHLE--TPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAH 153
             D  S LE    VD+I+ + VL  VA P  +++   ++LRPGG+L L   + H
Sbjct: 234 VGDTRSALEQSVSVDVIVMNMVLHHVASPADMIRDCAALLRPGGMLILSDLSRH 287


>UniRef50_A5EL18 Putative methyltransferase n=1 Tax=Bradyrhizobium sp. BTAi1
           RepID=A5EL18_BRASB
          Length = 271

 Score = 55.5 bits (132), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 39/106 (36%), Positives = 56/106 (52%), Gaps = 12/106 (11%)

Query: 47  RVLDAGGGEGQTAIKMAE----RGHQVILCDLSAQM-IDRAKQAAEAKGVSDNMQFIHCA 101
           RVLD G G G+ A   A     +GH V +  L +++ I R +Q       S N+ F    
Sbjct: 46  RVLDVGTGTGRLAEFAAHLVGPKGHVVGIDPLESRIAIARLRQ-------STNLVFDTGR 98

Query: 102 AQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSL 147
           A+D++       D+I F++VL W+AD R+VL     VLRPGG + L
Sbjct: 99  AEDLSRFAAGEFDVIYFNSVLHWIADKRTVLAEAQRVLRPGGRIGL 144


>UniRef50_A8M9S1 Methyltransferase type 11 n=1 Tax=Caldivirga maquilingensis IC-167
           RepID=A8M9S1_CALMQ
          Length = 262

 Score = 55.5 bits (132), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 36/118 (30%), Positives = 63/118 (53%), Gaps = 6/118 (5%)

Query: 34  LDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSD 93
           L   L+  G +  ++LD G G G+ AI +A+ G +VI  D+S   I+ A + A  +GV+D
Sbjct: 35  LSDYLSRRGLRNCKILDVGSGVGRVAIPLAKLGFKVIGIDISQDFINEAIKRATREGVND 94

Query: 94  NMQFIHCAAQDVASHLE----TPVDLILFHAVLEW--VADPRSVLQTLWSVLRPGGVL 145
           N+ F+   A++++S +       V L +F  V+ +       S+L+ +  V  PG +L
Sbjct: 95  NVVFLLGDARELSSVIRHYAPFNVTLFMFTTVIGYYDYETDLSILRQVHDVSGPGSLL 152


>UniRef50_Q73R34 Methlytransferase, UbiE/COQ5 family n=1 Tax=Treponema denticola
           RepID=Q73R34_TREDE
          Length = 250

 Score = 55.1 bits (131), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 35/101 (34%), Positives = 54/101 (53%), Gaps = 5/101 (4%)

Query: 47  RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFI--HCAAQD 104
           +VLDAG G G  AI +A+ G +V   D S  M++  K+ AE  G+SD + F+     + D
Sbjct: 47  KVLDAGCGTGFLAILLAQDGWEVTAIDSSEAMLEEGKKTAEELGLSDKITFLLKDAHSTD 106

Query: 105 VASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVL 145
              HL   V  +  HA   + A P +V +    +L+PGG++
Sbjct: 107 FPEHLFDAV--VSRHASWLFTA-PETVYKEWKRILKPGGIM 144


>UniRef50_B9XT55 Methyltransferase type 11 n=1 Tax=bacterium Ellin514
           RepID=B9XT55_9BACT
          Length = 291

 Score = 55.1 bits (131), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 44/155 (28%), Positives = 74/155 (47%), Gaps = 26/155 (16%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           F+ +A +F R+ YG  +        WQ   ++L  + P  L V D G GEG  +  +A +
Sbjct: 98  FNQVAGRFDRS-YGPGRS-------WQAFGQLLLRILP-PLTVADLGSGEGLLSELLALK 148

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETP------VDLILFH 119
             +VI  D S ++I+     A+  G+  N++F           LE P      VDL++  
Sbjct: 149 AKKVIAVDNSERIIEFGANKAKKNGLK-NLEF-------RLGDLENPPIDPHSVDLVILS 200

Query: 120 AVLEWVADPRSVLQTLWSVLRPGG---VLSLMFYN 151
             L   A+P   +Q+ + +L+PGG   +L L+ +N
Sbjct: 201 QALHHAAEPAKAIQSAYKILKPGGHIWILDLLKHN 235


>UniRef50_A4FLY1 Methyltransferase n=1 Tax=Saccharopolyspora erythraea NRRL 2338
           RepID=A4FLY1_SACEN
          Length = 244

 Score = 55.1 bits (131), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 60/237 (25%), Positives = 94/237 (39%), Gaps = 16/237 (6%)

Query: 29  ILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEA 88
           +L  +L +     G Q  RVLD GGG G  A+ +A  G  V + D S   +   ++ A  
Sbjct: 9   VLEAELAQARKRRGGQPPRVLDVGGGSGVWAVPLASAGCAVTVVDPSPNALATLQRRAAD 68

Query: 89  KGVSDNMQFIHCAAQDVASHLETP---VDLILFHAVLEWVADPRSVLQTLWSVLRPGGVL 145
            GV+D +  +       A H  +P    DL+L H +LE V D  + L+ + +   PGG +
Sbjct: 69  AGVADRITPLQGDTD--ALHAISPEGGADLVLGHGLLEVVDDVAAALREMAAATAPGGAV 126

Query: 146 SLMFYNAHGLLMHNMVAGN-------FDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEA 198
           S++  N H  ++   + G        F      +      TL   +  D   V   + EA
Sbjct: 127 SVLVANRHAAVLARALTGRVTEALKLFQDPDGRLHDCAADTLQRRFDSD--SVERAMREA 184

Query: 199 GWQIMGKTGVRVFHDYLREK--HQQRDCYEALLELETRYCRQEPYITLGRYIHVTAR 253
           G  +    G  V  D +            E+L ELE     + P   +   +H   R
Sbjct: 185 GMDVELIQGQGVLSDIVPGSVLESTTGAAESLAELERLAAARPPLRDIATRLHAIGR 241


>UniRef50_D1A8N4 Methyltransferase type 11 n=2 Tax=Streptosporangineae
           RepID=D1A8N4_THECD
          Length = 337

 Score = 55.1 bits (131), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 9/98 (9%)

Query: 47  RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA 106
           R++D G G G  +  +AERG QV+  D S +MI      A+A      + F+   A D  
Sbjct: 33  RIIDLGCGTGVFSAAIAERGAQVLGIDGSPEMI------AQAAATYPQLSFVVADAHDFT 86

Query: 107 SHLETPVDLILFHAVLEWVA-DPRSVLQTLWSVLRPGG 143
           +    P D +  +A L W+  DP +V++ ++  LRPGG
Sbjct: 87  T--SEPYDAVASNAALHWMTRDPDAVIKAVYKALRPGG 122


>UniRef50_A9G9E0 Putative uncharacterized protein n=1 Tax=Sorangium cellulosum 'So
           ce 56' RepID=A9G9E0_SORC5
          Length = 387

 Score = 54.7 bits (130), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 38/105 (36%), Positives = 57/105 (54%), Gaps = 8/105 (7%)

Query: 47  RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA 106
           R LD G G G+   +M  R H+ I  D +A M++RA Q A+A G+ DN+ F     + +A
Sbjct: 212 RCLDLGCGTGRLTREMGRRCHESIGIDATAAMVERAAQRAKALGL-DNVTF----REALA 266

Query: 107 SHLETP---VDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLM 148
           + L  P    D++    +L  + +P  VL     VLRPGG L+L+
Sbjct: 267 TRLPFPDASFDVVTASNLLLHLPEPGPVLAEAVRVLRPGGRLALL 311


>UniRef50_A6C296 UbiE/COQ5 methyltransferase n=2 Tax=Planctomycetaceae
           RepID=A6C296_9PLAN
          Length = 256

 Score = 54.7 bits (130), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 44/141 (31%), Positives = 67/141 (47%), Gaps = 8/141 (5%)

Query: 11  EKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVI 70
           E+F +  +G      R A  W D+ R     G    ++LD G G G  A+  AE GH + 
Sbjct: 26  ERFIKGEFGFAAS--RSA--WLDVLRKTVP-GEIPCKILDMGTGPGTIALLWAELGHAIT 80

Query: 71  LCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRS 130
             D SA MI   ++AA+ +G++  + F+  A  +     E   D+I   AVL  +  P  
Sbjct: 81  GVDFSATMISAGREAAKERGLT--VDFVE-ADVEAPPFPENTFDIISSRAVLFTLPHPGY 137

Query: 131 VLQTLWSVLRPGGVLSLMFYN 151
            +     +L+PGGVL L+  N
Sbjct: 138 AVAQWIRLLKPGGVLVLIGEN 158


>UniRef50_B3PI89 Biotin biosynthesis protein BioC n=2 Tax=Pseudomonadaceae
           RepID=B3PI89_CELJU
          Length = 502

 Score = 54.7 bits (130), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 44/142 (30%), Positives = 74/142 (52%), Gaps = 21/142 (14%)

Query: 9   IAEKFSRN--IYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERG 66
           +A+ F +    Y +  G L++A+  Q LD + A++   + R+LD G G G    ++A RG
Sbjct: 253 VAQSFGKAAATYDSVAG-LQRAVGAQLLDYLPAQL--DRTRLLDIGSGTGFFTAQLATRG 309

Query: 67  HQVILCDLSAQMIDRAK----QAAE-AKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
            +VI  D++  M+D A+    QAA+   G ++N+ F            ++ VD I    V
Sbjct: 310 AEVIALDIAQGMLDFARQQHPQAADWVCGDAENLPFA-----------QSSVDFIFSSLV 358

Query: 122 LEWVADPRSVLQTLWSVLRPGG 143
           ++W A    ++Q L  VL+PGG
Sbjct: 359 IQWCARVPQLMQELARVLKPGG 380


>UniRef50_Q2FPT3 UbiE/COQ5 methyltransferase n=1 Tax=Methanospirillum hungatei JF-1
           RepID=Q2FPT3_METHJ
          Length = 252

 Score = 54.7 bits (130), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 37/116 (31%), Positives = 62/116 (53%), Gaps = 5/116 (4%)

Query: 30  LWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAK 89
           LW++  R +  +G  K  VLD G G G  AI +AE GH V   DL  +M+D A + AE+K
Sbjct: 41  LWKNQLRTI--IGDDKKDVLDFGTGTGMIAINLAELGHSVTGIDLCEEMLDIANRKAESK 98

Query: 90  GVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVL 145
            +S  ++F+   A++     +   D+++   +L  +  P   ++    + RPGGV+
Sbjct: 99  DLS--IRFLLGDAEN-PEFPDRMFDVVICRHLLWTLPHPDVAIREWSRICRPGGVI 151


>UniRef50_A3TVS9 Methyltransferase, UbiE/COQ5 family protein n=1 Tax=Oceanicola
           batsensis HTCC2597 RepID=A3TVS9_9RHOB
          Length = 207

 Score = 54.7 bits (130), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 39/112 (34%), Positives = 57/112 (50%), Gaps = 5/112 (4%)

Query: 36  RVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNM 95
           R  + +GP   RVL+ G G G  A+K+A     V+  DLS  ++D A+Q A   GV +N+
Sbjct: 31  RAASYLGPDA-RVLEVGCGTGTIALKLAPHAAVVLATDLSGALLDIARQRAADAGV-ENV 88

Query: 96  QFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSL 147
            F   A  D+    E   D ++   V+  + D    L  + S +RPGGVL L
Sbjct: 89  GFARHAVDDLP---EGGFDAVMSFNVVHLIEDMDGALGAMASRVRPGGVLVL 137


>UniRef50_Q2FMN6 UbiE/COQ5 methyltransferase n=1 Tax=Methanospirillum hungatei JF-1
           RepID=Q2FMN6_METHJ
          Length = 253

 Score = 54.3 bits (129), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 42/144 (29%), Positives = 75/144 (52%), Gaps = 8/144 (5%)

Query: 6   FDDIAEKFS-RNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
           +D+ AE++  ++ +G    +   A  W +L +      P  + VLD G G G+ ++ +AE
Sbjct: 16  WDESAERYDMQHAHGVQSEEEHTA--WVNLFKQFTSDTP--ITVLDIGCGTGEMSLLLAE 71

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
            GH V   DLS  M+ RA+  A  KG S  + F    A+ + S+ +   DL++   +L  
Sbjct: 72  MGHSVHAIDLSENMLKRAEDKARKKGYS--ISFSIDDAESL-SYDDESFDLVINRHLLWT 128

Query: 125 VADPRSVLQTLWSVLRPGGVLSLM 148
           + DP   L+    VL+P G+++++
Sbjct: 129 LPDPEKALREWNRVLKPRGMIAVI 152


>UniRef50_Q467Y8 Methyltransferase n=2 Tax=Methanosarcina RepID=Q467Y8_METBF
          Length = 248

 Score = 54.3 bits (129), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 41/141 (29%), Positives = 69/141 (48%), Gaps = 24/141 (17%)

Query: 44  QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQ 103
           + L +LD G G GQ A+  AE GH V   DLS +M+D+A++ A  + +  ++ FI    Q
Sbjct: 45  EHLEILDVGTGPGQLALMFAELGHHVTAVDLSTRMLDKARKNALKRSL--DINFI----Q 98

Query: 104 DVASHLETP---VDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNM 160
             A +L+ P    D++    +L  + DP+  L     VL+  G++               
Sbjct: 99  GDAENLQLPDMQFDVVSSKFLLWTLPDPQKALSEWKRVLKKDGMI--------------- 143

Query: 161 VAGNFDYVQAGMPKKKKRTLS 181
           +A + D+  +G+  K  RT+S
Sbjct: 144 IAIDGDWFNSGIFLKSIRTIS 164


>UniRef50_C6D045 Methyltransferase type 11 n=24 Tax=Bacillales RepID=C6D045_PAESJ
          Length = 241

 Score = 54.3 bits (129), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 35/100 (35%), Positives = 47/100 (47%), Gaps = 5/100 (5%)

Query: 48  VLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVAS 107
           VLDAG   G    + AERG QV   DLS +M+     AA  + V D    + C       
Sbjct: 48  VLDAGCAAGWYTSQFAERGAQVTAIDLSPEMV-----AACRRRVGDKANVLVCELGQTLP 102

Query: 108 HLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSL 147
             E   DLI+    L ++ D  SV + +  VL+PGG+L  
Sbjct: 103 FEEESFDLIVSSLTLHYIEDWGSVFREMRRVLKPGGMLQF 142


>UniRef50_B3PGF3 Transcriptional regulator, ArsR family n=1 Tax=Cellvibrio japonicus
           Ueda107 RepID=B3PGF3_CELJU
          Length = 345

 Score = 54.3 bits (129), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 34/98 (34%), Positives = 51/98 (52%), Gaps = 2/98 (2%)

Query: 48  VLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVAS 107
            L+ G GEG+    ++ +  QVI  D +A M+D+A++ A  K +  N++FIH     + S
Sbjct: 185 ALEVGPGEGEFLALLSPQFDQVIALDNAANMLDKARRFAAGKQLR-NIEFIHGDTASLPS 243

Query: 108 HLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVL 145
           H +   D IL + VL     P  + Q L   L PGG L
Sbjct: 244 H-KVLADCILVNMVLHHTPSPADIFQDLSRALVPGGAL 280


>UniRef50_C1ZJC9 Methylase involved in ubiquinone/menaquinone biosynthesis n=1
           Tax=Planctomyces limnophilus DSM 3776 RepID=C1ZJC9_PLALI
          Length = 434

 Score = 54.3 bits (129), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 38/141 (26%), Positives = 70/141 (49%), Gaps = 5/141 (3%)

Query: 46  LRVLDAGGGEGQTAIKMAER----GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCA 101
           LRVL AGGG G + + +A +      +++  DLS      A++    +G+  + ++IH +
Sbjct: 60  LRVLIAGGGTGDSVVYLAHQLRNTPSKLVYVDLSEASQRIARERILVRGLGKSFEWIHGS 119

Query: 102 AQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLL-MHNM 160
             D+        D I    VL  + DP   L+ L ++L P GV+ LM Y  +G + ++ M
Sbjct: 120 LLDLKPESIGTFDYINCSGVLHHLPDPDLGLRVLSALLNPQGVIGLMVYGQYGRMGIYQM 179

Query: 161 VAGNFDYVQAGMPKKKKRTLS 181
                  + A +P+++K  ++
Sbjct: 180 QEMLRKAIPANLPREEKLAMA 200


>UniRef50_Q46ER7 UbiE/COQ5 methyltransferase n=4 Tax=Methanosarcina
           RepID=Q46ER7_METBF
          Length = 253

 Score = 54.3 bits (129), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 34/120 (28%), Positives = 66/120 (55%), Gaps = 5/120 (4%)

Query: 24  QLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAK 83
            L +A  W+ + + +   G  KL VLD G G G+ ++  AE GH V   DLS +M+++ +
Sbjct: 33  SLEEADAWKSMFKKIIPEG--KLDVLDVGCGTGELSVLFAEMGHNVTGLDLSEKMMEKGR 90

Query: 84  QAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGG 143
             + ++G+S  ++F+   A++     E   D+++   +L  + +P++ ++    VLR GG
Sbjct: 91  LKSMSQGLS--IKFLKGDAEN-PPFDEKNFDVVITRHLLWTLPNPKTAVKNWNRVLRDGG 147


>UniRef50_D1JEE5 Putative uncharacterized protein n=1 Tax=uncultured archaeon
           RepID=D1JEE5_9ARCH
          Length = 253

 Score = 54.3 bits (129), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 38/144 (26%), Positives = 76/144 (52%), Gaps = 9/144 (6%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQK-LRVLDAGGGEGQTAIKMAE 64
           +D  ++ + RN+Y   K Q      W+ + +   E+G  + L +LD G G G  A+  AE
Sbjct: 16  WDRRSQTYDRNVY---KSQNAAEHFWKSILK--TEIGTDRNLNILDVGTGTGFLALLFAE 70

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
            GH+V   D+S  M+++++  A  + ++ N  F+H  A+++    +   D+++   +L  
Sbjct: 71  LGHKVTGIDISKSMLEKSRCNAYKQKLAVN--FMHGDAENLPFD-DGSFDIVMNRYLLWT 127

Query: 125 VADPRSVLQTLWSVLRPGGVLSLM 148
           + DP++ +     V++ GG L L+
Sbjct: 128 LPDPKTAVNEWSRVVKSGGKLILI 151


>UniRef50_A6GID5 Putative uncharacterized protein n=1 Tax=Plesiocystis pacifica
           SIR-1 RepID=A6GID5_9DELT
          Length = 215

 Score = 54.3 bits (129), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 34/121 (28%), Positives = 65/121 (53%), Gaps = 6/121 (4%)

Query: 17  IYGTTKGQLRQAILWQDLDRVLAEMGP-QKLRVLDAGGGEGQTAIKMAERGHQVILCDLS 75
           +Y      LR+ I ++  D     +G  +  +VLD G G G+ A++ A+RG  VI  D +
Sbjct: 28  VYYMANQYLRKGI-FERYDLTFQTVGDLEGKKVLDIGTGTGRFAVECAKRGADVIGIDFA 86

Query: 76  AQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASH-LETPVDLILFHAVLEWVADPRSVLQT 134
            +MI+ ++QAA   GV +  +F+     DV  H  +   D++L   + ++V +P ++++ 
Sbjct: 87  PKMIEFSRQAARRFGVEERCKFV---VGDVLEHDFDEQFDVVLALGLFDYVREPSALMER 143

Query: 135 L 135
           +
Sbjct: 144 I 144


>UniRef50_C6PBK3 Methyltransferase type 11 n=1 Tax=Thermoanaerobacterium
           thermosaccharolyticum DSM 571 RepID=C6PBK3_CLOTS
          Length = 211

 Score = 54.3 bits (129), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 29/100 (29%), Positives = 58/100 (58%), Gaps = 2/100 (2%)

Query: 46  LRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDV 105
           L V D G G G  A+++++   +V+  D+S +M+  AKQ AE  G+ +N+ F+  + + +
Sbjct: 42  LIVADIGTGSGFMALELSKYAREVVGIDVSDEMLKYAKQTAENAGI-NNIIFLKGSMEQI 100

Query: 106 ASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVL 145
              ++  +D++  + VL  V +P   +  +  +L+PGG+L
Sbjct: 101 PI-IDDSIDVVFSNMVLHHVENPFKGIMEIHRILKPGGML 139


>UniRef50_C5E313 KLTH0H09460p n=1 Tax=Lachancea thermotolerans CBS 6340
           RepID=C5E313_LACTC
          Length = 305

 Score = 54.3 bits (129), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 34/126 (26%), Positives = 60/126 (47%), Gaps = 7/126 (5%)

Query: 48  VLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSD--NMQFIHCAAQDV 105
            +D G G G + + + +   +V+ CD S+ M++ AK+  +   V D   +++  C A+D+
Sbjct: 56  AIDVGCGTGISTLPLLKSFERVVGCDPSSTMLESAKKFKDKITVKDINRIEYSVCGAEDL 115

Query: 106 ASHLET-PVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMH---NMV 161
            S   +  +DL+     + WV + R   Q    VL+P G L+  FY     + H   N +
Sbjct: 116 TSLFASDSIDLVTGAESIHWVDEERFFKQAF-QVLKPNGTLAYWFYVEPIFIEHPQANEI 174

Query: 162 AGNFDY 167
              F Y
Sbjct: 175 YEEFVY 180


>UniRef50_A0RF06 Ubiquinone/menaquinone biosynthesis methyltransferase n=31
           Tax=Bacillaceae RepID=A0RF06_BACAH
          Length = 238

 Score = 54.3 bits (129), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 33/109 (30%), Positives = 52/109 (47%), Gaps = 8/109 (7%)

Query: 38  LAEMGPQKL---RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDN 94
           + EM P+ L    +LDAG   G    +  ERG  V   D+S++M+  AK++ + K     
Sbjct: 38  MMEMIPKNLEGKNILDAGCAAGWYTSQFIERGANVTAIDVSSEMVKAAKESMDNKAT--- 94

Query: 95  MQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGG 143
             F+    QDV    +   D+I+    L ++ +   V Q    VL+PGG
Sbjct: 95  --FLCHDLQDVLPFEDNTFDIIVSSLTLHYLQNWNQVFQEFRRVLKPGG 141


>UniRef50_C6A0V9 Cyclopropane-fatty-acyl-phospholipid synthase superfamily n=3
           Tax=Thermococcus RepID=C6A0V9_THESM
          Length = 245

 Score = 53.9 bits (128), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 34/129 (26%), Positives = 71/129 (55%), Gaps = 10/129 (7%)

Query: 32  QDLDRVLAEMG-PQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKG 90
           +++D +L E   P+  ++LD G G G+ ++++A+RG++V   D+S +M+++A++ A+ +G
Sbjct: 28  KEIDFLLEEFKLPEGAKILDVGCGVGRHSLELAKRGYRVTGVDISQKMLEKAEERAQKEG 87

Query: 91  VSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVA---DP----RSVLQTLWSVLRPGG 143
           V   ++FI   A   A + +    + L       +    DP     ++L+ ++  L+PGG
Sbjct: 88  V--EVEFIKADATKFARNEKFDAAVCLCEGAFSLLGSSDDPIEHDLAILRNVYKSLKPGG 145

Query: 144 VLSLMFYNA 152
              L   +A
Sbjct: 146 KFILTALSA 154


>UniRef50_Q8TJ84 UbiE/COQ5 methyltransferase n=1 Tax=Methanosarcina acetivorans
           RepID=Q8TJ84_METAC
          Length = 251

 Score = 53.9 bits (128), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 35/107 (32%), Positives = 54/107 (50%), Gaps = 9/107 (8%)

Query: 47  RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA 106
           ++LD G G G  ++ +A+ G++V+  DLS +MI RA   A+ +G+S +        QD A
Sbjct: 49  KILDIGSGTGFLSLMLADMGYEVVGIDLSEEMIARASAKAKERGLSIDFH------QDDA 102

Query: 107 SHL---ETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFY 150
             L       D I+  AVL  +  P   ++    VLRPGG L    +
Sbjct: 103 EQLGFENNSFDAIVNRAVLWTLPHPDIAVREWMRVLRPGGKLCFFLH 149


>UniRef50_D1CH64 Methyltransferase type 11 n=1 Tax=Thermobaculum terrenum ATCC
           BAA-798 RepID=D1CH64_THET1
          Length = 293

 Score = 53.9 bits (128), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 36/104 (34%), Positives = 52/104 (50%), Gaps = 3/104 (2%)

Query: 48  VLDAGGGEGQTAIKMAER-GHQ--VILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQD 104
           VLD G G G  A    ER G Q  VI  D S  ++D  +Q A  + V D  +FI  +A  
Sbjct: 53  VLDIGTGTGLLAFGALERVGKQGIVIFNDTSKALLDYCRQKATQEQVIDRCRFIQASATK 112

Query: 105 VASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLM 148
           +       +D ++  AVL +V +  +V + +  VL+PG  LSL 
Sbjct: 113 LTEIESDSIDAVVIRAVLIFVTNRVNVFEEIHRVLKPGARLSLF 156


>UniRef50_B1KQ47 Ubiquinone biosynthesis O-methyltransferase n=3 Tax=Shewanella
           RepID=B1KQ47_SHEWM
          Length = 270

 Score = 53.9 bits (128), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 45/168 (26%), Positives = 78/168 (46%), Gaps = 24/168 (14%)

Query: 6   FDDIAE-------KFSRNI-YGTTKGQLRQAILWQDLDRVLAEMGP-QKLRVLDAGGGEG 56
           FD +AE       KF   + +  T+    Q ++ +   R L +  P   L +LD G G G
Sbjct: 25  FDALAEEWRDPQGKFKHVLAFNLTRLTAIQMMIAEHFKRDLTQDIPFNDLTMLDIGCGVG 84

Query: 57  QTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPV--- 113
                ++++G  V   D S   ID A+Q AE   ++ N Q  HC A+D+ +     +   
Sbjct: 85  LLCEPLSKQGAHVTGIDASCYNIDLARQHAEKNNININYQ--HCLAEDLLAKQPINIANN 142

Query: 114 ----------DLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYN 151
                     D++L   V+E V D +++++T   +++PGG+L +   N
Sbjct: 143 QSDRIGSKHYDVVLNTEVIEHVEDQQALIKTCCELVKPGGILIMATLN 190


>UniRef50_C9L9K2 SmtA protein n=6 Tax=Bacteria RepID=C9L9K2_RUMHA
          Length = 564

 Score = 53.9 bits (128), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 39/134 (29%), Positives = 64/134 (47%), Gaps = 4/134 (2%)

Query: 22  KGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDR 81
           + +L   I  + L  +L  +  +KL++LD G G G   I MA++GH+VI  DL+A MI R
Sbjct: 347 RAELHDDIAQRWLKEILQYVPKKKLKILDVGCGSGFFTILMAQQGHEVIGVDLTADMITR 406

Query: 82  AKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRP 141
           AK+ A  +      Q +     + A   +   D+++   +   + D          VL+ 
Sbjct: 407 AKELAAEEKADCTFQVMDAENLEFA---DEAFDMVISRNLTWTLPDAERAYSEWLRVLKK 463

Query: 142 GGVLSLMFYNAHGL 155
           GG L L F   +G+
Sbjct: 464 GGCL-LNFDANYGI 476


>UniRef50_D1JD56 Putative uncharacterized protein n=1 Tax=uncultured archaeon
           RepID=D1JD56_9ARCH
          Length = 267

 Score = 53.9 bits (128), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 32/104 (30%), Positives = 55/104 (52%), Gaps = 3/104 (2%)

Query: 40  EMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIH 99
           E+   KL +LDAG G G  A+ +A  GH V+  DLS  M+ RA + A+ +G++ +++   
Sbjct: 50  EIVGNKLSILDAGTGTGFLALSLAGMGHDVVGIDLSEGMLSRAIKKAKERGLNLDLRMGD 109

Query: 100 CAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGG 143
             + D     +   D+++   VL  +  P   ++    VL+PGG
Sbjct: 110 VESLDFD---DKSFDVVVTRWVLWTLIHPDKAIEEWLRVLKPGG 150


>UniRef50_C8SD34 Methyltransferase type 11 n=1 Tax=Ferroglobus placidus DSM 10642
           RepID=C8SD34_FERPL
          Length = 246

 Score = 53.5 bits (127), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 40/128 (31%), Positives = 69/128 (53%), Gaps = 7/128 (5%)

Query: 30  LWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAK 89
           +W++   VLAE+   K+R+LD G G G  A+ +AE GH+V+  D+S +M+  A++ A  K
Sbjct: 31  VWKE---VLAEIFEDKMRILDVGTGTGFLAVILAELGHEVVGIDISEEMLKVARRKAVDK 87

Query: 90  GVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMF 149
           GV   + F    A+++    E   D  +   VL  + +P   +     V++ GG + ++ 
Sbjct: 88  GV--RIDFRVGDAENLPFDDEE-FDAAVCRHVLWTLPNPERAISEWKRVVKKGGKVVIID 144

Query: 150 YN-AHGLL 156
            N  HG+L
Sbjct: 145 GNWEHGIL 152


>UniRef50_B0BXU1 Methyltransferase n=14 Tax=Rickettsia RepID=B0BXU1_RICRO
          Length = 440

 Score = 53.5 bits (127), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 34/115 (29%), Positives = 59/115 (51%), Gaps = 5/115 (4%)

Query: 44  QKLRVLDAGGGEGQTAIKMAE----RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIH 99
              R L AGGG G + I +AE    +  ++I  D S   ++ A++ AE +G+  N+++I+
Sbjct: 64  NNFRCLIAGGGTGDSTIYLAEQLKDKNAEIIYLDFSKPSMEVAQKRAEVRGLR-NIKWIN 122

Query: 100 CAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHG 154
            +  ++ +      D I    VL  +A+P   L+ L   L+P G + LM Y  +G
Sbjct: 123 DSILNIPNLKLGKFDYINCTGVLHHLANPDEGLKNLKDSLKPTGGMGLMVYAKYG 177


>UniRef50_Q8TIG9 Putative uncharacterized protein n=1 Tax=Methanosarcina acetivorans
           RepID=Q8TIG9_METAC
          Length = 220

 Score = 53.5 bits (127), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 39/146 (26%), Positives = 66/146 (45%), Gaps = 13/146 (8%)

Query: 6   FDDIAEKFS------RNIY-GTTKGQLRQAILWQDLDRVLAEMGPQK-LRVLDAGGGEGQ 57
           F+ IAE F       +N+        LR+  L + L   LA   P++ +R+L+ G G G+
Sbjct: 19  FETIAEDFDAYYDKPKNMTDALINSWLRRPGLLKRLKITLAISDPKEGMRILEIGCGSGK 78

Query: 58  TAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLIL 117
             ++ A+RG  V   D++ +MI  AKQ      +       H +  D    L++  D+ +
Sbjct: 79  YIVECAKRGADVWGIDVAPEMIKLAKQFCNKSKIK-----AHLSVGDATKELQSGFDVCV 133

Query: 118 FHAVLEWVADPRSVLQTLWSVLRPGG 143
              V E+  DPR +L  + +     G
Sbjct: 134 ALGVFEYFKDPRPILNNMIAATNHNG 159


>UniRef50_Q28QS3 Methyltransferase type 11 n=1 Tax=Jannaschia sp. CCS1
           RepID=Q28QS3_JANSC
          Length = 261

 Score = 53.5 bits (127), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 37/125 (29%), Positives = 61/125 (48%), Gaps = 8/125 (6%)

Query: 47  RVLDAGGGEGQTAIKMAERGH---QVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQ 103
           RVLD G G G  A ++A++     +V+  D+S QM+DRA Q +E   +S       CA  
Sbjct: 40  RVLDIGSGPGFLAAQIADQSGPDGEVVGIDISEQMVDRATQRSEHSWLS-----YRCADA 94

Query: 104 DVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAG 163
                 ++  D+++   V E+V D       ++ VL+PGG   ++  +  G+  H+   G
Sbjct: 95  TELPFEDSYFDVVVSTQVAEYVPDIAKFCSEVFRVLKPGGRALILATDWEGVCWHSEYPG 154

Query: 164 NFDYV 168
             D V
Sbjct: 155 RMDKV 159


>UniRef50_D2QHG7 Methyltransferase type 11 n=1 Tax=Spirosoma linguale DSM 74
           RepID=D2QHG7_9SPHI
          Length = 259

 Score = 53.5 bits (127), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 36/123 (29%), Positives = 63/123 (51%), Gaps = 11/123 (8%)

Query: 24  QLRQAILWQDLDRVLAEMGPQK-LRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRA 82
           Q + A ++   + VL  + PQ   R+LD G G G+   ++AE G ++I  D S  MI +A
Sbjct: 14  QQKHAFVFHFGEDVLNLLDPQPGERILDLGCGTGELTARIAESGAKIIGLDASLSMISKA 73

Query: 83  KQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPR--SVLQTLWSVLR 140
           +++        ++ F    A++  +  + P D I  +A L W+ +    SVL  ++  L+
Sbjct: 74  RESFP------HLSFQEGDARNFGT--DQPFDAIFSNATLHWINETEQPSVLAAVFKALK 125

Query: 141 PGG 143
           PGG
Sbjct: 126 PGG 128


>UniRef50_C6IWT0 Putative uncharacterized protein n=1 Tax=Paenibacillus sp. oral
           taxon 786 str. D14 RepID=C6IWT0_9BACL
          Length = 177

 Score = 53.5 bits (127), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 27/59 (45%), Positives = 41/59 (69%), Gaps = 1/59 (1%)

Query: 44  QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAA 102
           ++LRVLD GGG G+ +I +AE+GH+V L DLS + ++ A+  AE +GV+    +IH  A
Sbjct: 65  KRLRVLDIGGGPGRYSIYLAEQGHEVTLLDLSKRHLEVARTKAEERGVTLK-DYIHGNA 122


>UniRef50_Q0UJE1 Putative uncharacterized protein n=1 Tax=Phaeosphaeria nodorum
           RepID=Q0UJE1_PHANO
          Length = 222

 Score = 53.1 bits (126), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 30/101 (29%), Positives = 46/101 (45%)

Query: 47  RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA 106
           RVLDAG G G  A+ MA  G  V   D++   +  AK+     G+ D ++  +    +++
Sbjct: 76  RVLDAGAGSGYVAMTMARHGLNVQAIDITPHHVANAKKNVRGYGLQDRIKVDYANYHNLS 135

Query: 107 SHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSL 147
              +   D I          DP  VL     +L+PGGV+ L
Sbjct: 136 QFPDASFDGIYTMETFVHADDPIKVLNNFKRLLKPGGVVVL 176


>UniRef50_A9B3A0 Methyltransferase type 11 n=1 Tax=Herpetosiphon aurantiacus ATCC
           23779 RepID=A9B3A0_HERA2
          Length = 211

 Score = 53.1 bits (126), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 50/174 (28%), Positives = 84/174 (48%), Gaps = 23/174 (13%)

Query: 32  QDLDRVLAEMGPQKLRVLDAGGGEG-QTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKG 90
           QDL + LA++     +VLD+G G G  TA  +A+ GH V   ++SA M++ A+Q      
Sbjct: 33  QDLSQWLADLLEPNSKVLDSGCGTGIPTAQTLAKAGHAVTCLEISASMLNLARQNVP--- 89

Query: 91  VSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV-ADPRSVLQTLWSVLRPGGVLSLMF 149
              N Q++  +   V     +   ++ F A+L    +D    LQ     L+P G      
Sbjct: 90  ---NGQYVLDSVNHVNFEPASFDAVVSFFALLMLRRSDIEHALQQFHHWLKPAG------ 140

Query: 150 YNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIM 203
                LL+ +MV G+FDY+Q  +    +      YP+  AQ+   + ++G+QI+
Sbjct: 141 -----LLLLSMVEGDFDYIQIVL--GDQPVFVTAYPQ--AQLEALITKSGFQIL 185


>UniRef50_A5EVK0 Ubiquinone biosynthesis O-methyltransferase n=2
           Tax=Cardiobacteriaceae RepID=A5EVK0_DICNV
          Length = 231

 Score = 53.1 bits (126), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 47/178 (26%), Positives = 81/178 (45%), Gaps = 14/178 (7%)

Query: 48  VLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIH---CAAQD 104
           +LD G G G  +  +A  G QV   DLS+ MI  A+     + ++ N + I    C AQ+
Sbjct: 51  ILDIGCGGGLLSEALAREGAQVFGIDLSSSMIAAAEHHLSGQNLAINYRQISSHDCCAQN 110

Query: 105 VASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGN 164
                    D I+   +LE VA+P ++L+ ++++LRP G   L   N +      M+   
Sbjct: 111 ------EQYDHIVCMEMLEHVANPAAILRDIYALLRPNGFAFLSTVNRNKRAFFKMIVLA 164

Query: 165 FDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQR 222
            +Y+   +P+        D+ R P ++    E AG   +  +G+  +H   +  H  R
Sbjct: 165 -EYLTKLVPRGTHHY--ADFIR-PHELVTMAERAGLSAVALSGM-TYHPLRKSAHLSR 217


>UniRef50_C6C7H1 Methyltransferase type 11 n=3 Tax=Enterobacteriaceae
           RepID=C6C7H1_DICDC
          Length = 258

 Score = 53.1 bits (126), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 37/108 (34%), Positives = 53/108 (49%), Gaps = 5/108 (4%)

Query: 40  EMGPQK--LRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQF 97
           E  PQK  LRVLD G G G  A+ +A  GH+V   D++  M+D+A+  A A      + F
Sbjct: 49  EQAPQKPVLRVLDIGTGPGFFAVTLALAGHRVTAVDVTQAMLDQAR--ANAAHYRTTIDF 106

Query: 98  IHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVL 145
           +H     +    +   DL++   V   + DP+   Q    VL PGG L
Sbjct: 107 VHSDVHAL-PFADNGFDLVVSRNVTWNLTDPQRAYQEWRRVLAPGGRL 153


>UniRef50_B5IUZ3 Methyltransferase, UbiE/COQ5 family n=4 Tax=Thermococcaceae
           RepID=B5IUZ3_9EURY
          Length = 250

 Score = 53.1 bits (126), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 32/102 (31%), Positives = 56/102 (54%), Gaps = 7/102 (6%)

Query: 47  RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA 106
           +VLD   G G   +++A RG++V+  DL  +M+  A++ A+  G+  N++FIH  A D+ 
Sbjct: 44  KVLDLACGTGIPTVELARRGYEVVGLDLHEEMLRVARRKAQELGL--NIEFIHGDALDIN 101

Query: 107 SHLETPVDLILFHAVLEWVADPRSVLQTLWSV---LRPGGVL 145
              E     + F +++ +  D  ++ Q   SV   L+PGGV 
Sbjct: 102 FENEFDAVTMFFSSIMYF--DENAIKQLFNSVIKALKPGGVF 141


>UniRef50_B1I4Q7 Methyltransferase type 11 n=1 Tax=Candidatus Desulforudis
           audaxviator MP104C RepID=B1I4Q7_DESAP
          Length = 265

 Score = 53.1 bits (126), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 29/106 (27%), Positives = 55/106 (51%), Gaps = 4/106 (3%)

Query: 47  RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA 106
           R LD G G G+ ++ +AE+G  V   DLS +M++ A+    +     N+  +    +++ 
Sbjct: 42  RALDGGCGTGRLSLALAEKGLVVTGVDLSPRMLEVARNRTRSHA---NITLMQADVENL- 97

Query: 107 SHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNA 152
                  DL+    VLE+  +P + ++ LW +++PGG L +   N+
Sbjct: 98  PFPSLSFDLVTAFTVLEFTGNPEAAVRELWRLVKPGGRLVVGVLNS 143


>UniRef50_Q2B0R2 Methyltransferase n=1 Tax=Bacillus sp. NRRL B-14911
           RepID=Q2B0R2_9BACI
          Length = 226

 Score = 53.1 bits (126), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 35/103 (33%), Positives = 53/103 (51%), Gaps = 9/103 (8%)

Query: 43  PQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHC-- 100
           P    V D G G+G   +K+A  G++V   D+S +MI +A +  E     ++ +FI    
Sbjct: 45  PAGSAVCDLGCGDGFGTLKLANAGYKVTGADVSEEMIHKAIKVNEG----NDARFIKSDI 100

Query: 101 AAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGG 143
           A+ DV  H     D +L    LEW   P +VL+ +  V+RPGG
Sbjct: 101 ASLDVPDH---AFDAVLAINSLEWTESPLAVLREMQRVVRPGG 140


>UniRef50_A8TN55 Methyltransferase n=3 Tax=Alphaproteobacteria RepID=A8TN55_9PROT
          Length = 415

 Score = 53.1 bits (126), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 39/117 (33%), Positives = 52/117 (44%), Gaps = 6/117 (5%)

Query: 44  QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQA---AEAKGVS---DNMQF 97
           +  R L AGGG G  AI +A+        D     +D +K +   AEA+       NM+F
Sbjct: 53  RPFRALVAGGGTGDAAIMLAQHLATAGAADAEVVYLDLSKASRRIAEARAAERRLTNMRF 112

Query: 98  IHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHG 154
           +    +DV      P D I    VL  +A P + LQ L   L P G L LM Y  +G
Sbjct: 113 VTGVIEDVDRLAPGPYDYIDCCGVLHHLASPEAGLQALADQLAPTGGLGLMLYGTYG 169


>UniRef50_A9UU62 Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9UU62_MONBE
          Length = 809

 Score = 52.8 bits (125), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 37/123 (30%), Positives = 60/123 (48%), Gaps = 13/123 (10%)

Query: 41  MGPQKLRVLDAGGGEGQT-----AIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNM 95
           + P +L  +D G G  +         +  R  ++ + D+SA ++D A++  EA G+SD +
Sbjct: 553 LPPGELTWVDVGAGTARNLEFFPVDTLKRRFKKIYILDISASLLDVARRRVEAAGLSDVV 612

Query: 96  QFIHCAAQDVA----SHLETP--VDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSL-- 147
           + +     D++    S L  P  VDL+ F   L  + D RS LQ    +L PGG L +  
Sbjct: 613 ELVLADFTDLSDKGKSALPAPGSVDLVTFSYSLSMIPDKRSALQQATRLLAPGGSLGIAD 672

Query: 148 MFY 150
            FY
Sbjct: 673 FFY 675


>UniRef50_A9GTB2 Methyltransferase n=1 Tax=Sorangium cellulosum 'So ce 56'
           RepID=A9GTB2_SORC5
          Length = 209

 Score = 52.8 bits (125), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 40/139 (28%), Positives = 69/139 (49%), Gaps = 10/139 (7%)

Query: 6   FDDIAEKFS-RNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
           +DDIAEK++ + +   T  + ++AI  + L             VL+ G G G  A++M+ 
Sbjct: 8   WDDIAEKYAAKPVENVTAFERKKAITRERLR--------PGSTVLEIGCGTGSLALEMSP 59

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
               +   D+S +MI  A Q  +A+GV+ N+ F        A +     D    +++L  
Sbjct: 60  FAGHIHAMDVSGEMIRIANQKKQAQGVT-NVTFRQGTLDGPAPYEPEHFDSAWAYSILHL 118

Query: 125 VADPRSVLQTLWSVLRPGG 143
           V D R  L+T++ +L+PGG
Sbjct: 119 VPDRRRTLKTVFDLLKPGG 137


>UniRef50_A0QIL0 Thiopurine S-methyltransferase (Tpmt) superfamily protein n=19
           Tax=Mycobacterium RepID=A0QIL0_MYCA1
          Length = 250

 Score = 52.8 bits (125), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 60/223 (26%), Positives = 85/223 (38%), Gaps = 32/223 (14%)

Query: 32  QDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGV 91
           Q + R L  +G  K  VLD G G G  AI  A +G      D SA  I+RA+  A   GV
Sbjct: 38  QPVVRQLVALGAVKGEVLDPGTGPGHHAIYYASQGFSATGIDGSAAAIERARANARTAGV 97

Query: 92  SDNMQFIHCAAQD-VASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFY 150
           S N +       D      +T VD   +H          S  + L    +PG  L +  +
Sbjct: 98  SVNFELADATKLDGFDGRFDTVVDCAFYHVFATEPELRSSYARALHRATKPGARLYMFEF 157

Query: 151 NAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQI--MGKTGV 208
             H +    M+                R+LS +  RD       L  AGW+I  +G T  
Sbjct: 158 GEHDVNGFKMM----------------RSLSENDFRD------VLPAAGWEISYLGPTTY 195

Query: 209 RVFHDYLREKHQ-----QRDCYEALLELETRYCRQEPYITLGR 246
           +V  +   E  Q       D  +   +L  R+   EP++  GR
Sbjct: 196 QV--NLSAETIQMMAARNPDMADEAAKLLERFRAMEPWLQAGR 236


>UniRef50_A8MFN6 Methyltransferase type 11 n=1 Tax=Alkaliphilus oremlandii OhILAs
           RepID=A8MFN6_ALKOO
          Length = 268

 Score = 52.4 bits (124), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 50/232 (21%), Positives = 98/232 (42%), Gaps = 24/232 (10%)

Query: 43  PQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAA 102
           P+   ++D G G G+ ++++ +RG+ V L DLS   ++ AK+  E   +    +  +C +
Sbjct: 41  PRTGNIIDIGSGPGRYSLELLKRGYHVSLLDLSKNELEIAKKKIEESNL--KAEHYYCKS 98

Query: 103 QDVASHLETP-VDLI-----LFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLL 156
                 LE    D +     L+H  L    +   VL+  + +L+ GGV  + + N  G L
Sbjct: 99  ALELDFLEDEFFDGVLVMGPLYH--LHGAQEREKVLKDTYRILKKGGVALISYINTWGAL 156

Query: 157 MHNMV--------AGNFD-YVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTG 207
             ++           +F+ Y++  +    + + +  +   P      +EE+G+ I+   G
Sbjct: 157 KASVSEFPESFEDEAHFERYIKGDLRFSSEESFTATFFTTPPLALKEVEESGFTIVSYAG 216

Query: 208 VRVFHDYLREKHQQR-----DCYEALLELETRYCRQEPYITLGRYIHVTARK 254
              F   L  + Q         Y+  LE   +YC    Y     ++H+  +K
Sbjct: 217 AESFLSGLNIQLQNLHKYMPHVYKNYLEAAPKYCELPQYRDATEHLHIIVQK 268


>UniRef50_A1AM59 Methyltransferase type 11 n=2 Tax=Pelobacter RepID=A1AM59_PELPD
          Length = 195

 Score = 52.4 bits (124), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 5/121 (4%)

Query: 36  RVLAEMGPQKLRVLDAGGGEGQTAIKMAE---RGHQVILCDLSAQMIDRAKQAAEAKGVS 92
           R+L     + +  LD G G G  ++ MA    +  +V+  D+  +M+D+    A   G++
Sbjct: 38  RILGPYVQEGMTALDLGCGFGHYSLGMARLTGKTGKVVAVDVQQKMLDKTMGRARGDGLA 97

Query: 93  DNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNA 152
           D +Q + C    +   L   +D  L    L    DPR +L  L+ +L PGG+  LM    
Sbjct: 98  DIIQPLLCDGHGIGLPLR--LDFALASNSLHETPDPRRLLSELFGMLSPGGLFLLMEPGV 155

Query: 153 H 153
           H
Sbjct: 156 H 156


>UniRef50_A5MZZ8 Predicted methyltransferase n=2 Tax=Clostridium kluyveri
           RepID=A5MZZ8_CLOK5
          Length = 251

 Score = 52.4 bits (124), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 38/123 (30%), Positives = 70/123 (56%), Gaps = 13/123 (10%)

Query: 32  QDLDRVLAEMGPQ-KLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKG 90
           +DLDR++  + PQ + +VLD   G G TAIK+A+   QV   D++ +M+  AK+ +   G
Sbjct: 28  RDLDRMIKLLNPQPEDKVLDVATGTGHTAIKLAQYTQQVEAIDITREMLYEAKKQSYENG 87

Query: 91  VSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVA-----DPRSVLQTLWSVLRPGGVL 145
           ++ N++F     +DV  +++ P +   FH V+  +A     + +  L+ +  VL+ GG L
Sbjct: 88  IT-NIEF---RIEDV-HNMKIPDN--TFHIVVCRLAAHHFSNIKMALKEMCRVLKTGGKL 140

Query: 146 SLM 148
            ++
Sbjct: 141 YIL 143


>UniRef50_B1L3G9 Methyltransferase type 11 n=1 Tax=Candidatus Korarchaeum
           cryptofilum OPF8 RepID=B1L3G9_KORCO
          Length = 273

 Score = 52.4 bits (124), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 37/113 (32%), Positives = 61/113 (53%), Gaps = 4/113 (3%)

Query: 37  VLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQ 96
           +L E G +  RVL+A  G G+ AI +A  G+ V+  D+S   I  A+Q AE   VSD  +
Sbjct: 46  ILRENGLESGRVLEAFCGNGRVAIPLAIEGYDVLGFDISLPFIQDARQKAEKHRVSDKAK 105

Query: 97  FIHCAAQDVASHLETPV-DLILFHAVLEWVADPRS---VLQTLWSVLRPGGVL 145
           FI   A+++ S L+  + D I+  +      D  +   +L+ L S+++ G +L
Sbjct: 106 FIVSDAREIDSRLKGEIFDAIIIVSTSLGYYDSMTDEEILRKLRSLVKEGSIL 158


>UniRef50_B6R6V6 Methyltransferase, UbiE/COQ5 family n=1 Tax=Pseudovibrio sp. JE062
           RepID=B6R6V6_9RHOB
          Length = 210

 Score = 52.4 bits (124), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 31/112 (27%), Positives = 62/112 (55%), Gaps = 3/112 (2%)

Query: 34  LDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSD 93
           +DRV + + P++  VL+ G G G TA+ +A+    +   D+S +MI+  ++ A   G+ +
Sbjct: 30  MDRVRSYLTPEQ-EVLELGCGSGSTAMLLAKHVKHMTASDISGKMIEFGQEKAWNDGI-E 87

Query: 94  NMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVL 145
           N+ F+H  A       ++  D+++   V+  +  P SVL+ +  +L+P G+ 
Sbjct: 88  NISFVHTPAGSSVFEGKS-YDVVMAFNVVHLIKGPASVLKQVHRMLKPDGLF 138


>UniRef50_A4X1E6 Methyltransferase type 11 n=5 Tax=Actinobacteria (class)
           RepID=A4X1E6_SALTO
          Length = 266

 Score = 52.4 bits (124), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 40/119 (33%), Positives = 59/119 (49%), Gaps = 7/119 (5%)

Query: 36  RVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNM 95
           R+L E+  +   VLD   G G  A ++  RG +VI  D S +M+   ++      V   +
Sbjct: 68  RLLGEVAGRT--VLDVACGPGLYAEELVARGARVIGLDQSPRMVHLCRER-----VPSGV 120

Query: 96  QFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHG 154
             +H  A+ +    +  VDL+LF   LE+V D RS L+ L  VLRP G L L   +  G
Sbjct: 121 FHVHDLAERLHWLPDESVDLVLFALALEYVDDRRSTLRELRRVLRPDGALVLSRLHPTG 179


>UniRef50_B8FRY0 Methyltransferase type 12 n=2 Tax=Desulfitobacterium hafniense
           RepID=B8FRY0_DESHD
          Length = 242

 Score = 52.4 bits (124), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 42/148 (28%), Positives = 69/148 (46%), Gaps = 7/148 (4%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M +  FD +A  +  + Y T  G L   +  +    +    GPQ   VL+ G G GQ   
Sbjct: 1   MNEALFDPVAAHYD-SWYDTELGSLSDQVERRLAQSMFKAPGPQ---VLEIGCGTGQYTS 56

Query: 61  KMAERGHQVILCDLSAQMIDRA-KQAAEAKGVSDNMQFIHCAAQDVASHLET--PVDLIL 117
            + + G++V   D+S +M+  A K+ A  +  +   + +H    D+   L+     D I 
Sbjct: 57  WLLQEGYEVTAVDISGKMMALAQKKIATLQETTPQAKPVHWWHGDITEILDQLGTYDGIF 116

Query: 118 FHAVLEWVADPRSVLQTLWSVLRPGGVL 145
                E+V +P +VL+ L+S L PGG L
Sbjct: 117 SMTAFEFVPEPETVLKKLFSRLNPGGCL 144


>UniRef50_A8MFN7 Methyltransferase type 11 n=1 Tax=Alkaliphilus oremlandii OhILAs
           RepID=A8MFN7_ALKOO
          Length = 266

 Score = 52.4 bits (124), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 46/218 (21%), Positives = 96/218 (44%), Gaps = 19/218 (8%)

Query: 47  RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA 106
           R+L+ G G G  +    E+G+ VI  D++ + I+   Q  + +G   N+Q     A D++
Sbjct: 43  RILEIGAGTGAYSFYYGEKGNFVIATDITPKHIEIIGQKMKERGNDINLQAEVANATDLS 102

Query: 107 SHLETPVDLIL-----FHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMV 161
                  D++L     +H  L   +D ++ L     VL+ GG+L++ + N H +L   M+
Sbjct: 103 QFSSESFDVVLCLGPMYH--LTNSSDRKTCLSEALRVLKKGGLLAIAYINKHFVLNSVMI 160

Query: 162 AG------NF--DYVQAGMPKKKKRTL--SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVF 211
                   NF    +  G+ ++ ++    +  +   P ++  ++     +I+   GV   
Sbjct: 161 RNKEFLTRNFIDKILDTGVTREGEKECFWTDAFFTTPDEMASYMNCFEVEIIDHLGVDGL 220

Query: 212 HDYLRE--KHQQRDCYEALLELETRYCRQEPYITLGRY 247
             Y ++       + YE+ L    R CR++  + +  +
Sbjct: 221 SPYFKDAVDGMNSEEYESWLYYNMRSCREKSILGISNH 258


>UniRef50_Q7U920 Putative uncharacterized protein n=1 Tax=Synechococcus sp. WH 8102
           RepID=Q7U920_SYNPX
          Length = 299

 Score = 52.0 bits (123), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 33/140 (23%), Positives = 59/140 (42%), Gaps = 10/140 (7%)

Query: 30  LWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQV-ILCDLSAQMIDRAKQAAEA 88
           ++Q    ++  + P+    +D G G G  +  +        I CD+S   +   +     
Sbjct: 119 MYQFYKSIVVPVLPKSGLFIDVGVGTGFYSRNLLRDSQMTGIGCDMSPHSLSYTRSTLSK 178

Query: 89  KGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLM 148
            G  D   F  C       + ++  D IL   VLE + DP  +L++L+  L+PGG+    
Sbjct: 179 FGTVDKYSFCLCDYYHFNQYFQSTADFILSIEVLEHLEDPMKMLESLYKSLKPGGL---- 234

Query: 149 FYNAHGLLMHNMVAGNFDYV 168
                GL+   + A N D++
Sbjct: 235 -----GLISAAVNAPNADHI 249


>UniRef50_C0ZCL2 Putative uncharacterized protein n=1 Tax=Brevibacillus brevis NBRC
           100599 RepID=C0ZCL2_BREBN
          Length = 247

 Score = 52.0 bits (123), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 37/101 (36%), Positives = 54/101 (53%), Gaps = 10/101 (9%)

Query: 46  LRVLDAGGGEGQTAIKMAERG-HQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQD 104
           LRVLD G G GQ A    E+G  +VI  DLS  M++ A+         +N+Q++H + +D
Sbjct: 44  LRVLDLGCGGGQFARYCVEQGASEVIGVDLSHNMLEYAR----TNNSHENIQYLHGSLED 99

Query: 105 V--ASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGG 143
           +  ASH     DLI    V+++V D   V+  +   LR GG
Sbjct: 100 IELASH---DYDLITSSLVMDYVRDYEHVINKISRALRNGG 137


>UniRef50_Q97TL7 SAM-dependent methyltransferase n=2 Tax=Clostridium
           RepID=Q97TL7_CLOAB
          Length = 254

 Score = 52.0 bits (123), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 38/156 (24%), Positives = 74/156 (47%), Gaps = 14/156 (8%)

Query: 47  RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA 106
           ++LD G G G    ++A+ G  VI  DLS  MID+AK          N+ F    A +++
Sbjct: 33  KILDLGCGTGVLTNELAKNGATVIGTDLSKNMIDKAKTNYP------NLIFQVKDATNLS 86

Query: 107 SHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFD 166
              +   D +  +AV  W+++   +L ++++ L+  G L   F   + +   + +   F+
Sbjct: 87  --FKNEFDTVFSNAVFHWISNQEKLLHSIYTCLKDNGTLICEFGAQNNI---SQIQTAFE 141

Query: 167 YVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQI 202
            V   + +K     SP +     +  L L++AG+++
Sbjct: 142 KV---IEQKGYSYCSPFFFPSKEEYKLLLDQAGFEV 174


>UniRef50_B3QX57 Methyltransferase type 11 n=1 Tax=Chloroherpeton thalassium ATCC
           35110 RepID=B3QX57_CHLT3
          Length = 266

 Score = 52.0 bits (123), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 44/148 (29%), Positives = 66/148 (44%), Gaps = 21/148 (14%)

Query: 34  LDRVL-AEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVS 92
           L R L A + P  L  LD   G G+ AI++A  G  V   DLS+ +++ A+QAA+  G  
Sbjct: 48  LSRALHASLFP--LSALDIACGAGRHAIELAAHGFAVTANDLSSFLLNEARQAAQKSGT- 104

Query: 93  DNMQFIHCAAQDV--ASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFY 150
             + F  C  +D+    +    V L       E + D R VL+ ++  L+  G   L F 
Sbjct: 105 -QLHFTGCDMRDIDYIDNFHLIVQLFTSFGYFENLEDDRHVLRKIYLALKENGWYVLDFL 163

Query: 151 NAHGLLMHNMVAGNFDYVQAGM-PKKKK 177
           N              DY++A + PK  K
Sbjct: 164 NK-------------DYIEANLNPKSVK 178


>UniRef50_A7I8W9 Methyltransferase type 11 n=3 Tax=Methanomicrobiales
           RepID=A7I8W9_METB6
          Length = 243

 Score = 52.0 bits (123), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 41/148 (27%), Positives = 65/148 (43%), Gaps = 20/148 (13%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
           +++D+IAE     +Y       R       + R + E  P+   +LD G G G    K  
Sbjct: 11  QHYDEIAE-----VYDLHYDHPRGRTYHTRISRHVMEALPRGGALLDIGCGTGLFVEKYL 65

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVS----DNMQFIHCAAQDVASHLETPVDLILFH 119
             G   +  DLS  MI+RA++     G +    +++ F   +   VAS L          
Sbjct: 66  HHGGSAVGIDLSRNMIERARRRCSCCGFTLGTGESLPFRDNSFDAVASLL---------- 115

Query: 120 AVLEWVADPRSVLQTLWSVLRPGGVLSL 147
            V  +V DP S+L   + V+RPGG +S+
Sbjct: 116 -VFSYVRDPESMLNEAYRVMRPGGAISI 142


>UniRef50_C5A2C6 SAM-dependent methyltransferase, ubiE/COQ5 family n=7
           Tax=Thermococcaceae RepID=C5A2C6_THEGJ
          Length = 228

 Score = 52.0 bits (123), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 46/184 (25%), Positives = 85/184 (46%), Gaps = 13/184 (7%)

Query: 32  QDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGV 91
           ++L+ +L +   +K +VLD G G G  +  + + G  V+  D S  M+  A+  A+ KG 
Sbjct: 26  ENLEPLLMKFMKEKGKVLDLGCGAGGFSFLLEDLGFTVVGVDNSEYMLSLARGFAKEKG- 84

Query: 92  SDNMQFIHCAAQDVASHLETPVDLILF--HAVLEWVADPRSVLQTLWSVLRPGGVLSLMF 149
              ++FI   A+++    +   D +LF  + V     D     + +  VL+PGG L L F
Sbjct: 85  -SKVEFIKADARELPFE-DNTFDYVLFIDNLVHFEPLDLGKAFREMARVLKPGGKLILQF 142

Query: 150 YNAHGL---LMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKT 206
            +   L   LM+  V G   ++   +P K ++T+  ++  +            + + GKT
Sbjct: 143 TDLRALLPVLMNGQVIGAEYWISKVLPDKDEKTVLIEFQSEEKSF-----RVRFNVWGKT 197

Query: 207 GVRV 210
            V +
Sbjct: 198 AVEL 201


>UniRef50_Q01YM7 Methyltransferase type 11 n=1 Tax=Candidatus Solibacter usitatus
           Ellin6076 RepID=Q01YM7_SOLUE
          Length = 272

 Score = 52.0 bits (123), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 33/106 (31%), Positives = 58/106 (54%), Gaps = 8/106 (7%)

Query: 46  LRVLDAGGGEGQTAIKMAER---GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAA 102
           +RVLD G G G   + ++E       VI  D+ A +++ A++     G+S N+ F H   
Sbjct: 44  MRVLDLGSGAGDVCMLLSEMVGPSGSVIGVDVDAGIVEHARERVAEAGLS-NVTFAH--- 99

Query: 103 QDVASH-LETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSL 147
            D+A++  + PVD ++   VL ++ DP + L  L   +RPGG+++ 
Sbjct: 100 SDLANYRADAPVDALVGRLVLCYLPDPSAPLAALSKSVRPGGIVAF 145


>UniRef50_C5FG45 Crg1p n=1 Tax=Microsporum canis CBS 113480 RepID=C5FG45_NANOT
          Length = 294

 Score = 52.0 bits (123), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 41/165 (24%), Positives = 69/165 (41%), Gaps = 9/165 (5%)

Query: 10  AEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQV 69
           +  FS   Y + + +  Q +     D V +         LD G G G  +  ++ R  +V
Sbjct: 6   SSNFSYTAYASFRPEYPQKLY----DMVFSYHQGAYNTCLDLGCGHGLVSRALSPRFKKV 61

Query: 70  ILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPR 129
              D SA MI++AK          N++F+  AA+ +    +  VDL++      W   P 
Sbjct: 62  YGIDPSAGMIEQAKNMT----TEQNVEFVQAAAESLPFIEDKSVDLVVAGVAAHWFNYP- 116

Query: 130 SVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPK 174
            +   L  V++PGG L+   Y+ H L+ +       D    G+ K
Sbjct: 117 PLFAELQRVMKPGGTLAFWGYSDHYLVDYPKATAVLDKYAYGLDK 161


>UniRef50_D1XAK7 Methyltransferase type 11 n=1 Tax=Streptomyces sp. ACT-1
           RepID=D1XAK7_9ACTO
          Length = 259

 Score = 52.0 bits (123), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 30/101 (29%), Positives = 45/101 (44%), Gaps = 3/101 (2%)

Query: 47  RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA 106
           R LD G  EG+ A+ +A RG      DLSA  +DRA +  +    +  + F+H  A D  
Sbjct: 52  RALDLGPAEGREAVFLARRGVATTGVDLSAAQVDRASRWWKD---TPGLTFVHAEAGDYL 108

Query: 107 SHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSL 147
           +    P D +       W  DP  +   +   L PGG+ + 
Sbjct: 109 TSSTMPFDTVYSVWGAVWFTDPELLFPLIARNLTPGGIFAF 149


>UniRef50_A7H6R5 Methyltransferase type 12 n=3 Tax=Anaeromyxobacter
           RepID=A7H6R5_ANADF
          Length = 198

 Score = 52.0 bits (123), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 39/120 (32%), Positives = 61/120 (50%), Gaps = 13/120 (10%)

Query: 38  LAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKG------V 91
           LA+ G  K  VLD G G G+ A+ +A  G +V+  D S   I RA++ A  +G      V
Sbjct: 32  LADEGEVKGTVLDVGCGTGENALHLASLGKRVVGVDGSRAAIARAREKAAERGLPVAFHV 91

Query: 92  SDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYN 151
           +D +Q      + +   +ET VD  LFH   +   + R   ++L  VL PGG L ++ ++
Sbjct: 92  ADALQL-----RRLHLRVETVVDCGLFHVFSD--EERRPYAESLTEVLSPGGTLHVLCFS 144


>UniRef50_Q3AS64 Methyltransferase, putative n=1 Tax=Chlorobium chlorochromatii CaD3
           RepID=Q3AS64_CHLCH
          Length = 262

 Score = 51.6 bits (122), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 51/188 (27%), Positives = 82/188 (43%), Gaps = 20/188 (10%)

Query: 38  LAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQF 97
           L +  P    VLD   G G+ AI++A RG+ V   DLS  +++ A +AA+ + +   +Q 
Sbjct: 52  LEQATPATTTVLDIACGAGRHAIELARRGYNVTGNDLSTTLLNEAAKAAKQEKLP--LQL 109

Query: 98  IHCAAQDVASH--LETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGL 155
            +   + V +H   +  V L       +  A+  +V+Q +W +L   G   L       L
Sbjct: 110 TNYDMRHVPTHQRYQLVVQLFTSFGYFDSKAEDGAVVQKVWELLHKNGWYVL------DL 163

Query: 156 LMHNMVAGNF---DYVQAG-MPKKKKRTLSPDYPR------DPAQVYLWLEEAGWQIMGK 205
           L  + +A NF      Q G +  K+KRTL  +  R       P+   L   EA W     
Sbjct: 164 LNPDYLAANFIAESQRQVGELTIKEKRTLEANRVRKELCILSPSGETLHFSEAVWLYSAD 223

Query: 206 TGVRVFHD 213
             V + H+
Sbjct: 224 EIVDILHN 231


>UniRef50_A5INN1 Methyltransferase type 12 n=12 Tax=Thermotogaceae
           RepID=A5INN1_THEP1
          Length = 266

 Score = 51.6 bits (122), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 33/130 (25%), Positives = 67/130 (51%), Gaps = 4/130 (3%)

Query: 32  QDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGV 91
           ++  ++L     +  +VLD   GEG  A+++A++G +V+  DLS +M++ A++ A+ + V
Sbjct: 38  KNFTKILENFHVRGKKVLDVACGEGTFAVEIAKQGFEVVGIDLSPEMLEFARKRAKEESV 97

Query: 92  SDNMQFIHCAAQDVASHLETPVDLILFHAV--LEWVADPRSVLQTLWSVLRPGGVLSLMF 149
              + F+    +++  H E  +    F ++  L   +D +   + +   L+ GG L    
Sbjct: 98  P--VVFLKKDMRELDFHEEFDIVTCWFDSLNYLLDYSDLKKTFEKVHEALKAGGALLFDM 155

Query: 150 YNAHGLLMHN 159
              +GLLM N
Sbjct: 156 NTVYGLLMAN 165


>UniRef50_A7MPA9 3-demethylubiquinone-9 3-methyltransferase n=6
           Tax=Gammaproteobacteria RepID=UBIG_ENTS8
          Length = 243

 Score = 51.6 bits (122), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 56/211 (26%), Positives = 91/211 (43%), Gaps = 29/211 (13%)

Query: 47  RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA 106
           +VLD G G G  +  MA  G  V   D+ A+ +  A+  A   GV  N  ++    ++ A
Sbjct: 59  KVLDVGCGGGILSESMAREGANVTGLDMGAEPLAVARLHALESGVELN--YVQQTVEEHA 116

Query: 107 SHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGG--VLSLMFYNAHGLLMHNMVAGN 164
           +      D++    +LE V DPRSV+Q    +++PGG    S +  NA   LM  + A  
Sbjct: 117 AQHAGAYDVVTCMEMLEHVPDPRSVVQACAQLVKPGGHVFFSTLNRNAKSWLMAVVGA-- 174

Query: 165 FDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDC 224
            +YV   +PK      +  + R P+++  W++E                 L E+H     
Sbjct: 175 -EYVLRMVPKGTHD--AKKFIR-PSELLGWVDETP---------------LEERHIIGLH 215

Query: 225 YEALLELETRYCRQEPYITLGRYIHVTARKP 255
           Y  L    T   +  P + +   +H  A+KP
Sbjct: 216 YNPL----TNRFKLAPGVDVNYMLHTQAKKP 242


>UniRef50_B2A8G5 Methyltransferase type 11 n=1 Tax=Natranaerobius thermophilus
           JW/NM-WN-LF RepID=B2A8G5_NATTJ
          Length = 264

 Score = 51.6 bits (122), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 36/117 (30%), Positives = 58/117 (49%), Gaps = 10/117 (8%)

Query: 47  RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA 106
           ++LD   G G+ AI MA+RG+QV+  DLS  +++ +K+ A    V D + FI    + + 
Sbjct: 52  KLLDLCSGSGRHAISMAKRGYQVMGLDLSNGLVEASKRRASESSVKDQVDFIQGDVRKLH 111

Query: 107 S-HLETPVD------LILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLL 156
              LET          + FH   +   D  ++L  ++ +L PGG L +   N   LL
Sbjct: 112 KLKLETNFKAAYCLATVGFHMTDQ---DFNNMLTGVYHLLDPGGYLIIDVINRENLL 165


>UniRef50_B0NQC1 Putative uncharacterized protein n=1 Tax=Bacteroides stercoris ATCC
           43183 RepID=B0NQC1_BACSE
          Length = 258

 Score = 51.6 bits (122), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 34/114 (29%), Positives = 55/114 (48%), Gaps = 8/114 (7%)

Query: 38  LAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQF 97
              + PQ  R+L+ G GEG   +  A  G +V   DLS   I +A+Q  + + +      
Sbjct: 30  FTSVTPQS-RILEIGCGEGGNLVPFARIGCRVTGIDLSENRIRQARQFFQEERLPATF-- 86

Query: 98  IHCAAQDVAS--HLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMF 149
               A D+     LE   D+IL H V+E +++   +L+ +   L PGG+L + F
Sbjct: 87  ---IASDIFQIIQLEEAFDIILIHDVIEHISEKYRLLEHIKRFLTPGGLLFISF 137


>UniRef50_Q0BV11 Methyltransferase n=1 Tax=Granulibacter bethesdensis CGDNIH1
           RepID=Q0BV11_GRABC
          Length = 412

 Score = 51.6 bits (122), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 39/115 (33%), Positives = 52/115 (45%), Gaps = 8/115 (6%)

Query: 46  LRVLDAGGGEGQTAIKMAE------RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIH 99
           LR L AGGG G   I +A       R   V   D S   +  A+  AE + ++  + F  
Sbjct: 56  LRALVAGGGTGDGTIMLATHLARDGRPGGVTYLDRSRAALQTAQARAEVRNLT--VDFRA 113

Query: 100 CAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHG 154
            +  D+ +    P D I    VL  + DP   L+ L SVL PGG + LM Y  HG
Sbjct: 114 GSILDLPAVAPGPFDYIDCCGVLHHLPDPAEGLRALTSVLAPGGGMGLMVYAPHG 168


>UniRef50_B8H209 3-demethylubiquinone-9 3-methyltransferase n=13
           Tax=Alphaproteobacteria RepID=UBIG_CAUCN
          Length = 252

 Score = 51.2 bits (121), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 37/119 (31%), Positives = 58/119 (48%), Gaps = 3/119 (2%)

Query: 34  LDRVLAEMGP-QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVS 92
            DR  A   P + L +LD G G G  +  MA  G  V   D S + I  A   A  +G+ 
Sbjct: 57  FDRDGAARAPFEGLTLLDIGCGGGLLSEPMARLGFAVTAIDASEKNIKTAATHAAEQGL- 115

Query: 93  DNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYN 151
            ++ +    A+ + +    P D++L   V+E VADP   L+T   +L+PGG++ +   N
Sbjct: 116 -DIGYRPATAEQLLAEGAGPFDVVLTMEVIEHVADPGEFLRTCAKLLKPGGIMFVATLN 173


>UniRef50_C9CSA7 Methyltransferase, UbiE/COQ5 family n=1 Tax=Silicibacter sp.
           TrichCH4B RepID=C9CSA7_9RHOB
          Length = 211

 Score = 51.2 bits (121), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 30/98 (30%), Positives = 54/98 (55%), Gaps = 4/98 (4%)

Query: 48  VLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVAS 107
           +L+ G G G TA+ +A    Q++  D SA+MI+  ++ A A G+S N++F  C   D+ +
Sbjct: 43  ILELGCGTGSTAVTLAPNVAQMLATDFSAKMIEFGQERARAAGLS-NLKFQVC---DLET 98

Query: 108 HLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVL 145
               P D++L   +   + +  + LQ +   L+PGG+ 
Sbjct: 99  APVGPFDVVLAFNLFHLLPELDASLQKVAQRLKPGGLF 136


>UniRef50_A1D5R5 Putative uncharacterized protein n=1 Tax=Neosartorya fischeri NRRL
           181 RepID=A1D5R5_NEOFI
          Length = 278

 Score = 51.2 bits (121), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 41/143 (28%), Positives = 71/143 (49%), Gaps = 11/143 (7%)

Query: 21  TKGQLRQAILWQDLDRVLAEMG-PQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMI 79
           T  +L  +I W+ + + L ++G  + L +LD GGG G+ A+ +A+ GH V L D+S + +
Sbjct: 23  TSCRLEFSISWKIITQYLDQLGRGRALEILDLGGGTGRYALPLAKLGHSVTLVDISDREL 82

Query: 80  DRAKQAAEAKGVSDNMQFIHCAAQDVASH----LETPVDLILFHAVLEWVADP---RSVL 132
             A   AE   V      +   A+D+ S+     E   D++L    L  + +    R+VL
Sbjct: 83  KIAHSTAEEAQVKLT-AIVKADARDIRSNPVIFQEQKYDMVLCQGPLYHLLEENERRAVL 141

Query: 133 QTLWSVLRPGGVL--SLMFYNAH 153
               + L+P G++  + M   AH
Sbjct: 142 SACAAALKPSGIILAAFMLQYAH 164


>UniRef50_B3ENM4 Magnesium protoporphyrin O-methyltransferase n=7 Tax=Chlorobiaceae
           RepID=B3ENM4_CHLPB
          Length = 233

 Score = 51.2 bits (121), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 32/138 (23%), Positives = 69/138 (50%), Gaps = 12/138 (8%)

Query: 43  PQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAA 102
           P+   +LDAG G G  ++++A  G+ V   D++AQM++++++ A AKG+ + + F     
Sbjct: 65  PEDATILDAGCGTGLFSVRLAGNGYHVKAVDIAAQMVNKSREEATAKGLQEKIDFEVNTI 124

Query: 103 QDVASHLETPVDLILFHAVLEWVADP-RSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMV 161
           ++V    +    ++ F  ++ + A+      + L ++ +   + +   YN    L H   
Sbjct: 125 EEVKGMYDA---VVCFDVLIHYPAEGFMEAFKNLSNLTKGPIIFTYAPYNKILALQH--- 178

Query: 162 AGNFDYVQAGMPKKKKRT 179
                ++    PKK++RT
Sbjct: 179 -----WIGGFFPKKERRT 191


>UniRef50_A7NQ08 Methyltransferase type 11 n=5 Tax=Chloroflexaceae
           RepID=A7NQ08_ROSCS
          Length = 262

 Score = 51.2 bits (121), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 36/112 (32%), Positives = 51/112 (45%), Gaps = 6/112 (5%)

Query: 47  RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIH----CAA 102
           RVLD   G G+  + +A+ G +V   D SA MI+RA+    A GV+  +   H     A 
Sbjct: 44  RVLDVMCGSGRLLVPLAQAGMRVTGIDASAAMIERARMRVAATGVAPRIALYHGDVRSAV 103

Query: 103 QDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHG 154
            D   HL         H  L   AD  +VL  +   L P G+L++  +N H 
Sbjct: 104 PDGPYHLAIVALNSFMH--LTTTADQLAVLANIHRALHPDGLLAIDVFNPHA 153


>UniRef50_Q012C7 Dihydroxypolyprenylbenzoate methyltransferase (ISS) n=1
           Tax=Ostreococcus tauri RepID=Q012C7_OSTTA
          Length = 351

 Score = 50.8 bits (120), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 36/106 (33%), Positives = 52/106 (49%), Gaps = 2/106 (1%)

Query: 47  RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAK-QAAEAKGVSDNMQFIHCAAQDV 105
           RVLD G G G  A  +A  G  V   D     I+ A+  AA   G+   +++ H AA+ +
Sbjct: 159 RVLDVGCGGGIFAESLARLGADVTAIDAGLANIEIARAHAARDPGLDGRLRYEHVAAEAL 218

Query: 106 ASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYN 151
               ET  D +    V+E V+DP    ++L  ++RPGG L L   N
Sbjct: 219 GDRGET-FDAVTSLEVIEHVSDPMGFAKSLGKLVRPGGALFLSTIN 263


>UniRef50_C8W6C7 Methyltransferase type 11 n=1 Tax=Desulfotomaculum acetoxidans DSM
           771 RepID=C8W6C7_DESAS
          Length = 247

 Score = 50.8 bits (120), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 38/121 (31%), Positives = 61/121 (50%), Gaps = 11/121 (9%)

Query: 31  WQD-LDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAK 89
           W D ++ +L +       ++D   G G TA   A RG++V   DLSA+MID A++ AE +
Sbjct: 23  WIDYIEELLVKFEYSPKTIIDLACGTGNTAFPFARRGYRVAGVDLSARMIDIARKKAEKE 82

Query: 90  GVSDNMQFIHCAAQDVAS-HLETPVDLI-LFHAVLEWV---ADPRSVLQTLWSVLRPGGV 144
            +  N+ F     QD+    L  PV+LI  FH  L ++    D +   + ++  L  GG+
Sbjct: 83  NL--NINFF---VQDICCLKLPEPVELITCFHDGLNYLLNYEDIKLTFKKVFDNLLSGGL 137

Query: 145 L 145
            
Sbjct: 138 F 138


>UniRef50_A2CBD3 SAM (And some other nucleotide) binding motif:TPR repeat n=2
           Tax=Prochlorococcus marinus RepID=A2CBD3_PROM3
          Length = 780

 Score = 50.8 bits (120), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 38/118 (32%), Positives = 59/118 (50%), Gaps = 3/118 (2%)

Query: 35  DRVLAEMGPQKLRVLDAGGGEGQTAIK-MAERGHQVILCDLSAQMIDRAKQAAEAKGVSD 93
           +R+   +  Q+ RVL AG G GQ     ++     +   DLS+  I  AK+ A   G+ +
Sbjct: 524 NRISIILPKQRSRVLIAGCGTGQQIFDALSYSNSDLTAIDLSSSSIAYAKRKAHEYGI-E 582

Query: 94  NMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYN 151
           +++FI     D+   L    DLI    VL  + DP   LQ+L ++L   G+L L FY+
Sbjct: 583 HIRFIEMDILDLPK-LNEEFDLIECTGVLHHMKDPSEGLQSLLTILASDGMLKLGFYS 639


>UniRef50_B4B3H0 Methyltransferase type 11 n=1 Tax=Cyanothece sp. PCC 7822
           RepID=B4B3H0_9CHRO
          Length = 201

 Score = 50.8 bits (120), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 39/127 (30%), Positives = 59/127 (46%), Gaps = 8/127 (6%)

Query: 33  DLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVS 92
           D+D+ L+E+   +  VLD G G G  A+ +AERG  VI  DLS   ID+A   A+ + + 
Sbjct: 32  DVDKALSELNLDQAMVLDLGTGPGTQAMALAERGFNVIATDLSHSAIDKASSVAQQRRLE 91

Query: 93  DNMQFIHCAAQDV-ASHLETPVDLILFHAVLEWVADPRSV--LQTLWSVLRPGGVLSLMF 149
                I     D+  + L    DLIL       +A  R    +Q +  +L+P   L L  
Sbjct: 92  -----ITWKQDDILNTQLGEQFDLILDRGCFHVLAPERRADYVQVVARLLKPSKYLFLKT 146

Query: 150 YNAHGLL 156
           ++    L
Sbjct: 147 FSVSETL 153


>UniRef50_UPI00016BFDE3 SAM-dependent methyltransferase n=1 Tax=Epulopiscium sp. 'N.t.
           morphotype B' RepID=UPI00016BFDE3
          Length = 247

 Score = 50.8 bits (120), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 28/104 (26%), Positives = 52/104 (50%), Gaps = 8/104 (7%)

Query: 46  LRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDV 105
           + +LD G G G     + E+   +I  DLS +M++RAK           ++F++  A ++
Sbjct: 32  VSILDLGCGTGDLTATIFEKYKNIIGVDLSKEMLERAKSKYPE------IKFLNIDATNM 85

Query: 106 ASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMF 149
               +   D+I  +AVL W+ D   + + ++  L+ GG+L   F
Sbjct: 86  --KFKNKFDVIFSNAVLHWILDQEKLHKNIYKNLQKGGILVCEF 127


>UniRef50_Q1AZ81 Demethylmenaquinone methyltransferase n=1 Tax=Rubrobacter
           xylanophilus DSM 9941 RepID=Q1AZ81_RUBXD
          Length = 216

 Score = 50.8 bits (120), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 36/105 (34%), Positives = 54/105 (51%), Gaps = 5/105 (4%)

Query: 46  LRVLDAGGGEGQTAIKMAER---GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAA 102
           +RVLDAG G G+ A+  A R     +V+  D+   M+ R +     +G+  N++ +  AA
Sbjct: 70  MRVLDAGCGAGRLAVSAARRVGPAGEVVALDVREGMLSRLRGRVSREGLR-NVRAVR-AA 127

Query: 103 QDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSL 147
                  E   D +L   VL  V D  + L+ L+  LRPGGVLS+
Sbjct: 128 LGEGELEEGGFDRVLLAMVLGEVRDREAALRELYRALRPGGVLSV 172


>UniRef50_A4Z3A6 Putative uncharacterized protein n=1 Tax=Bradyrhizobium sp. ORS278
           RepID=A4Z3A6_BRASO
          Length = 242

 Score = 50.8 bits (120), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 36/110 (32%), Positives = 54/110 (49%)

Query: 47  RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA 106
           R LDAG G G  +  +A RG +V   D SA+MI RA+        +  ++F   A  +  
Sbjct: 55  RWLDAGCGTGTLSRLLAGRGCEVTGVDASAEMIRRARHLPTGSEQTGALRFDQIATIEAL 114

Query: 107 SHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLL 156
              +   D +L  +VLE+V D  + L+ +  VLR  G++ L   N   LL
Sbjct: 115 PFSDGAFDGVLCASVLEYVPDVPAALREIHRVLRVDGLVLLSIPNRASLL 164


>UniRef50_Q6MHC4 3-demethylubiquinone-9 3-methyltransferase n=1 Tax=Bdellovibrio
           bacteriovorus RepID=Q6MHC4_BDEBA
          Length = 284

 Score = 50.8 bits (120), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 43/165 (26%), Positives = 75/165 (45%), Gaps = 9/165 (5%)

Query: 45  KLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQD 104
           K  +LD G G G  A  +A  GH+V   DLS   +    + AE++ ++ ++ +       
Sbjct: 85  KAEILDMGCGAGFLANDLAAAGHKVTGIDLSTSSL----KVAESRDLTHSVHYRQGDVYQ 140

Query: 105 VASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGN 164
           V    E+  D++    +LE V+DP+ V+     VLRPGG+     +N + L    ++ G 
Sbjct: 141 VPFPNES-FDVVAAMDLLEHVSDPQRVIAEASRVLRPGGLFFFNTFNKNPLAWLVVIKGM 199

Query: 165 FDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVR 209
             +V+         +L      +P ++ LWLE+         G+R
Sbjct: 200 EWFVKNTPNDYHVYSLF----IEPKKLKLWLEDFSLDTQEIRGIR 240


>UniRef50_Q5WCE8 S-adenosylmethionine (SAM)-dependent methyltransferase n=3
           Tax=Bacillus RepID=Q5WCE8_BACSK
          Length = 261

 Score = 50.8 bits (120), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 31/100 (31%), Positives = 51/100 (51%), Gaps = 8/100 (8%)

Query: 44  QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQ 103
           +K  +LD G G G  A ++A+ G  V   D S+ M+      A+A+    ++ F    A 
Sbjct: 38  KKEAILDLGSGTGDLANELAKLGAVVTGVDQSSNMV------AKARSKYPHLLFDMADAT 91

Query: 104 DVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGG 143
           ++        D +L +AVL WV D  + L+++W  L+PGG
Sbjct: 92  NLP--FTETFDAVLSNAVLHWVLDAEAALKSIWRALKPGG 129


>UniRef50_D1BJP6 Methylase involved in ubiquinone/menaquinone biosynthesis n=1
           Tax=Sanguibacter keddieii DSM 10542 RepID=D1BJP6_SANKS
          Length = 305

 Score = 50.8 bits (120), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 37/105 (35%), Positives = 52/105 (49%), Gaps = 3/105 (2%)

Query: 43  PQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAA 102
           P+ +  L AG G G  A+     G QV   D +A M++R   +A+A G++D +   H   
Sbjct: 59  PRSIVDLGAGTGTGTLALAARFPGAQVHSLDATATMLERLTDSADAAGLTDRVT-THLVD 117

Query: 103 --QDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVL 145
              D  + L  PVDL      L  V+DP  VL+  +  L PGGVL
Sbjct: 118 LDGDWPAELPGPVDLAWAALSLHHVSDPGQVLRQAYGALAPGGVL 162


>UniRef50_D0NEB7 Trans-aconitate 2-methyltransferase, putative n=2 Tax=Phytophthora
           infestans T30-4 RepID=D0NEB7_PHYIN
          Length = 285

 Score = 50.4 bits (119), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 33/107 (30%), Positives = 51/107 (47%), Gaps = 4/107 (3%)

Query: 45  KLRVLDAGGGEGQTAIKMAER--GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAA 102
            + ++D G G G  A    +R     V   D S  M++ A+Q  +     +   F +  A
Sbjct: 45  SVEIIDLGAGTGNMAPSFQKRWPSAHVTFVDSSTSMLEVAQQEHDENETLNTQGFAYVQA 104

Query: 103 QDVASHLETPVDLILFHAVLEWV-ADP-RSVLQTLWSVLRPGGVLSL 147
                  E P +LI  +A L+WV AD  + +L  L+S L+PGGVL+ 
Sbjct: 105 DFETYAPERPGNLIFSNAALQWVSADKHKQILPRLYSFLKPGGVLAF 151


>UniRef50_C0VYW5 Possible ubiquinone/menaquinone biosynthesis methyltransferase n=1
           Tax=Actinomyces coleocanis DSM 15436 RepID=C0VYW5_9ACTO
          Length = 240

 Score = 50.4 bits (119), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 42/143 (29%), Positives = 69/143 (48%), Gaps = 11/143 (7%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           F+ +A+++       T GQLR    W+   R   ++GP + RVLD   G G +   + E 
Sbjct: 27  FNKVAKRYDLMNEIMTVGQLRT---WRKAVREALDVGPGQ-RVLDLAAGTGASTAALLET 82

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV 125
           G +++ CDLS  MI+  +Q          ++F+H  A D+    E+  D +     +  +
Sbjct: 83  GAELVACDLSEGMIEVGRQR------HPEIEFVHGNALDLPFSDES-FDAVTISFGIRNI 135

Query: 126 ADPRSVLQTLWSVLRPGGVLSLM 148
            D   VL  L  VL+PGG L ++
Sbjct: 136 PDTEKVLSELARVLKPGGRLVIL 158


>UniRef50_A8KYQ0 Methyltransferase type 12 n=2 Tax=Frankia RepID=A8KYQ0_FRASN
          Length = 246

 Score = 50.4 bits (119), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 39/105 (37%), Positives = 55/105 (52%), Gaps = 12/105 (11%)

Query: 48  VLDAGGGEGQTAIKMAE---RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQD 104
           VLDAG G G+    + E   RG +VI  D SA M+D      + +    + + +   A D
Sbjct: 36  VLDAGCGTGRDTAALLEALPRG-RVIAVDASASMLD------QLRARLPDTERLTILAAD 88

Query: 105 VASHLET--PVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSL 147
           +   L    PVD +L  AVL W+AD + V   L ++LRPGG LS+
Sbjct: 89  LLDPLPIAEPVDAVLSVAVLHWIADHQRVFDNLAAILRPGGRLSV 133


>UniRef50_D2PTC3 Methyltransferase type 11 n=1 Tax=Kribbella flavida DSM 17836
           RepID=D2PTC3_9ACTO
          Length = 230

 Score = 50.4 bits (119), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 38/113 (33%), Positives = 60/113 (53%), Gaps = 16/113 (14%)

Query: 34  LDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSD 93
           +D +L  +G   LRV D G GEG  A+++AE G QV+  D SA M+  A+          
Sbjct: 35  VDALLPPVG--GLRVADLGCGEGSLAVRLAESGAQVVAVDASAAMLANARP-------HP 85

Query: 94  NMQFIHCAAQDVASHLETP---VDLILFHAVLEWVADPRSVLQTLWSVLRPGG 143
            +++I C   D+A  LE P   +DL++    L +V D   +++ + + L PGG
Sbjct: 86  GVRYIRC---DLA-ELELPADSIDLVVSSLALHYVEDFSGLVRRVAAWLVPGG 134


>UniRef50_UPI0000E48A5D PREDICTED: hypothetical protein n=4 Tax=Strongylocentrotus
           purpuratus RepID=UPI0000E48A5D
          Length = 638

 Score = 50.4 bits (119), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 32/105 (30%), Positives = 53/105 (50%), Gaps = 3/105 (2%)

Query: 46  LRVLDAGGGEGQTAIKMAER--GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQ 103
           +R+LD G G G  ++  AE      V+  D S + I+  K+ A+ KG++ N++FI   A 
Sbjct: 453 IRILDLGCGRGLASLAFAESYPNSTVVGLDFSEEAINYGKERAKEKGLT-NVEFIREDAA 511

Query: 104 DVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLM 148
            +       +D I    V+  +A    VL  L  +L+P GV S++
Sbjct: 512 CIPDDWNNTIDYIYTFNVIHDLAHADKVLLALNRILKPDGVFSMI 556


>UniRef50_D2RYJ5 Methyltransferase type 11 n=3 Tax=Haloterrigena turkmenica DSM 5511
           RepID=D2RYJ5_9EURY
          Length = 226

 Score = 50.4 bits (119), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 32/107 (29%), Positives = 59/107 (55%), Gaps = 3/107 (2%)

Query: 42  GPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCA 101
           G    R LD G G G  ++ +AE GH V   DLS  M++RA+  A+A+    +++F +  
Sbjct: 52  GDPPRRTLDVGCGTGVISLLLAELGHVVTGVDLSTDMLERAR--AKARDRDRSVEFRNGD 109

Query: 102 AQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLM 148
           A+ +++  E   DL+    ++  + +P + ++    V+RPGG + L+
Sbjct: 110 AESISAP-ENAYDLVTARHLVWTLPNPLAAIREWQRVVRPGGRIVLI 155


>UniRef50_B0A8V1 Putative uncharacterized protein n=1 Tax=Clostridium bartlettii DSM
           16795 RepID=B0A8V1_9CLOT
          Length = 255

 Score = 50.4 bits (119), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 31/104 (29%), Positives = 55/104 (52%), Gaps = 3/104 (2%)

Query: 42  GPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCA 101
           G ++L+VLD G G G  +I ++  G+ V   D + +M+++AKQ   A  + D ++F    
Sbjct: 50  GDRRLKVLDIGCGPGFFSIILSCAGYDVTAVDYTEEMLNKAKQ--NAGDLKDKIKFRRMD 107

Query: 102 AQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVL 145
           A ++    E   DLI+   +   + DP    ++ + VLR GG +
Sbjct: 108 AHNLEFD-EGQFDLIVTRNLTWNLKDPEKAYKSWYKVLRKGGKM 150


>UniRef50_C6DDT8 Biotin biosynthesis protein BioC n=6 Tax=Enterobacteriaceae
           RepID=C6DDT8_PECCP
          Length = 253

 Score = 50.4 bits (119), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 44/152 (28%), Positives = 70/152 (46%), Gaps = 21/152 (13%)

Query: 2   QDRNFDDIAEKFSRNIYGTTK-GQLRQAILWQDLDRVLAEMGPQK-LRVLDAGGGEGQTA 59
           ++ N   IA+ F R   G  +  +L++       +R+L  M P   L VLDAG G G  +
Sbjct: 4   ENYNKQAIAQAFGRAAGGYDRFAELQRT----SGERLLTLMPPHGGLLVLDAGCGTGHFS 59

Query: 60  IKMAERGHQVILCDLSAQMIDRAKQAAEA----KGVSDNMQFIHCAAQDVASHLETPVDL 115
               +RG  VI  DLSA M+ +A++   A    +G  +N+    C+           VD+
Sbjct: 60  RHWRQRGKTVIALDLSAAMLAQAREQQAADRYQEGDIENLPLADCS-----------VDI 108

Query: 116 ILFHAVLEWVADPRSVLQTLWSVLRPGGVLSL 147
              +  ++W       L  L+ V RPGGV++ 
Sbjct: 109 SYSNLAVQWCDSLPRALAELYRVTRPGGVIAF 140


>UniRef50_B4RIP1 Tetratricopeptide repeat/protein kinase domain protein n=1
           Tax=Phenylobacterium zucineum HLK1 RepID=B4RIP1_PHEZH
          Length = 758

 Score = 50.4 bits (119), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 39/110 (35%), Positives = 59/110 (53%), Gaps = 4/110 (3%)

Query: 47  RVLDAGGGEGQTAIKMAE--RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQD 104
           RVL AG G G   +++A   RG  ++  DLSA  +  A + A A G+++ M+ +     D
Sbjct: 512 RVLVAGCGTGLETMRVATTYRGASILAIDLSAASLGYAMRKARAYGLTE-MEHLQADILD 570

Query: 105 VASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHG 154
           + S  E   DLI    VL  +A+P + LQ L ++LRP G L +  Y+  G
Sbjct: 571 LPSLGER-FDLIDSFGVLHHMAEPATGLQVLGTLLRPDGFLFVGLYSEIG 619


>UniRef50_D1NAT1 Trans-aconitate 2-methyltransferase n=1 Tax=Victivallis vadensis
           ATCC BAA-548 RepID=D1NAT1_9BACT
          Length = 257

 Score = 50.4 bits (119), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 34/117 (29%), Positives = 58/117 (49%), Gaps = 8/117 (6%)

Query: 47  RVLDAGGGEGQTAIKMAER--GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQD 104
           RVLD G G G +   +AER  G  ++  D SA MI+ A++   A      ++F    A  
Sbjct: 34  RVLDLGCGPGNSTRVLAERFPGAHILGVDNSANMIEAARRDYPA------LEFRLFDATG 87

Query: 105 VASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMV 161
             + L    D++  +A ++WV D   +L+ +   L PGGV+++   N     +H ++
Sbjct: 88  DFAELGGSYDVVFSNACIQWVPDHPRLLRNMMGQLAPGGVMAVQIPNNFDAPVHRII 144


>UniRef50_B3E3C6 Methyltransferase type 12 n=1 Tax=Geobacter lovleyi SZ
           RepID=B3E3C6_GEOLS
          Length = 215

 Score = 50.4 bits (119), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 38/147 (25%), Positives = 71/147 (48%), Gaps = 10/147 (6%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGP-QKLRVLDAGGGEGQTAI 60
           Q R+F+ +A ++ +      + QL  A+     + ++   GP Q +RVLD G G G   +
Sbjct: 6   QLRDFNAVAARWDQE---PRRVQLASAVS----EAIIRNAGPSQAMRVLDFGAGTGLVTL 58

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
            +A    Q++  D S  M+++        G+++ + F+   A  V+  L  P DLI+   
Sbjct: 59  ALAPLVQQMVAADSSQGMLEQLTAKLADAGITNVLPFLLDHAGPVS--LPGPFDLIVSSM 116

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSL 147
            +  +ADP ++     + +R GG L +
Sbjct: 117 TMHHIADPGTLFGLFHAAMRSGGQLCI 143


>UniRef50_Q21DX2 Methyltransferase type 11 n=2 Tax=Gammaproteobacteria
           RepID=Q21DX2_SACD2
          Length = 212

 Score = 50.1 bits (118), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 41/161 (25%), Positives = 76/161 (47%), Gaps = 15/161 (9%)

Query: 45  KLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQD 104
           K+R+L+ G G G TAI  A     +   D+S  M++  ++ A   GV+ N+ F      +
Sbjct: 44  KMRLLEFGCGTGTTAIHHASHVLHIDAIDISENMLNIGREKASNAGVA-NITFTRSTLTE 102

Query: 105 VASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGN 164
             +   + +D +L   V+  + D +SVL  +  +L+PGGV           +   +  GN
Sbjct: 103 FNAGAAS-LDAVLGLNVIHLLPDRQSVLTEVARILKPGGV----------FVSSTVCLGN 151

Query: 165 --FDYVQAGMPKKKKRTLSPD-YPRDPAQVYLWLEEAGWQI 202
             F +++  +P  K   + PD Y    +++   + +AG+ I
Sbjct: 152 SYFRFIKPFVPLGKFLGVMPDVYVLTESELASEVRDAGFTI 192


>UniRef50_C0CIH7 Putative uncharacterized protein n=1 Tax=Blautia hydrogenotrophica
           DSM 10507 RepID=C0CIH7_9FIRM
          Length = 256

 Score = 50.1 bits (118), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 37/111 (33%), Positives = 54/111 (48%), Gaps = 12/111 (10%)

Query: 46  LRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDV 105
           L VLD G G G  AI  A RGH+V   D++ +M+  A++ A   GV  N        Q V
Sbjct: 60  LNVLDIGTGPGFFAILAALRGHKVTAVDMNGKMLVNARKNARRAGVQVNF-------QQV 112

Query: 106 ASHLETP---VDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAH 153
              L  P    DLIL   V   + +P   L+T   +L+  G  +L++++A 
Sbjct: 113 GHELPFPEKSFDLILSRDVTWTLTEPEKQLRTWVRILKEEG--TLLYFDAE 161


>UniRef50_A9FQ40 3-demethylubiquinone-9 3-O-methyltransferase n=1 Tax=Sorangium
           cellulosum 'So ce 56' RepID=A9FQ40_SORC5
          Length = 234

 Score = 50.1 bits (118), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 34/105 (32%), Positives = 53/105 (50%), Gaps = 10/105 (9%)

Query: 49  LDAGGGEGQTAIKMAERGHQVILCDLSAQMID--RAKQAAEAKGVSDNMQFIHCAAQDVA 106
           LD G G G  +  +A+RG  V  CDL   +++  R +   EA  V+D ++ +    +D  
Sbjct: 52  LDVGCGLGYFSEALAKRGAIVTACDLGPNLVEATRKRVGCEAV-VADALRLVDQFGRD-- 108

Query: 107 SHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYN 151
                  DL+L    +E   DP++ L+ +  VL+PGG LSL   N
Sbjct: 109 -----RFDLVLSSECIEHTPDPQACLRQMAGVLKPGGYLSLSTPN 148


>UniRef50_C4NCJ8 SAM-dependent methyltransferase n=1 Tax=Streptomyces sp. MK730-62F2
           RepID=C4NCJ8_9ACTO
          Length = 210

 Score = 50.1 bits (118), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 37/110 (33%), Positives = 54/110 (49%), Gaps = 8/110 (7%)

Query: 27  QAILWQDLDRVLAEMGP-QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQA 85
           QA  W  L   LAE+ P    R+LD G G G  ++ +AE G  V   D S +M++RA+  
Sbjct: 27  QAAAWGAL---LAEVYPVHTGRLLDIGCGTGTYSLLIAELGFDVHGVDTSERMVERARAK 83

Query: 86  AEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTL 135
           A  +G    + F    AQD++       D +    VL  VADP  + +T+
Sbjct: 84  ALERGAGPGVSFSTLPAQDISGQY----DAVFSRNVLWTVADPGRLAETV 129


>UniRef50_Q21UL3 3-demethylubiquinone-9 3-methyltransferase n=5 Tax=Proteobacteria
           RepID=UBIG_RHOFD
          Length = 252

 Score = 50.1 bits (118), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 37/128 (28%), Positives = 63/128 (49%), Gaps = 16/128 (12%)

Query: 31  WQDLD---RVLAEMGPQKL------------RVLDAGGGEGQTAIKMAERGHQVILCDLS 75
           W DL+   R L ++ P +L            +VLD G G G  A  MA  G QV   DL+
Sbjct: 34  WWDLEGEFRPLHQINPLRLEWINHLCPVAGQQVLDVGCGGGILADSMARLGAQVTGIDLA 93

Query: 76  AQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTL 135
           ++ + R  Q    +  + N+Q+   + + +A+      D++    +LE V DP SV++  
Sbjct: 94  SKAL-RVAQLHALEAQTPNLQYQEISVEALAAQQPGSFDVVTCMEMLEHVPDPASVVRAC 152

Query: 136 WSVLRPGG 143
            ++++PGG
Sbjct: 153 ATLVKPGG 160


>UniRef50_UPI0001B57FBF MCP methyltransferase, CheR-type n=1 Tax=Streptomyces sp. AA4
           RepID=UPI0001B57FBF
          Length = 246

 Score = 50.1 bits (118), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 56/190 (29%), Positives = 87/190 (45%), Gaps = 15/190 (7%)

Query: 25  LRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERG-HQVILCDLSAQMIDRAK 83
           +R+ + W      L ++  +  RVLD G GEG    ++ + G  QV+  DLS  MI  A+
Sbjct: 25  VRENLEWPSFKNALGDL--RGARVLDVGCGEGSFTRRIKQLGAAQVVGTDLSPGMIALAR 82

Query: 84  QAAEAKGVSDNMQFIHCAAQDVAS-HLETPVDLILFHAVLEWVADPRSVLQTLWSV---- 138
           Q AEA+    N   I    QD+A+  L+   D++    VL + AD R  +QT+       
Sbjct: 83  Q-AEAR----NPLGITHEVQDLAAMPLQGEFDVVTAIHVLHY-ADTRETMQTMAKTMHAN 136

Query: 139 LRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSP-DYPRDPAQVYLWLEE 197
           L+PGG L+++  NA         AG   Y  A   +  K  ++    P    +V+ W  E
Sbjct: 137 LKPGGRLAVLSANADSSEESETAAGFRTYRPANPQEGDKFKVAVLTTPPTEIEVHHWPTE 196

Query: 198 AGWQIMGKTG 207
              +I+   G
Sbjct: 197 TIVEILETAG 206


>UniRef50_C9N8D9 Methyltransferase type 11 n=6 Tax=Streptomyces RepID=C9N8D9_9ACTO
          Length = 244

 Score = 50.1 bits (118), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 40/135 (29%), Positives = 69/135 (51%), Gaps = 7/135 (5%)

Query: 30  LWQDLDRVLAEMGPQKLRVLDAGGGEGQT--AIKMAERGHQVILCDLSAQMIDRAKQAAE 87
           L +   R+    G + LR+LD G G G +  A+  A    ++   D SA M++RA+    
Sbjct: 34  LLRSAHRLRLPRGGRGLRLLDLGCGTGASTRALLRAAPYARITAVDASAGMLERAR---- 89

Query: 88  AKGVSDNMQFIHCAAQDV-ASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLS 146
           AK    N++F+H +A+++  +  +   D +    +   VA+P  VL+ + ++LRPGG L 
Sbjct: 90  AKRWPANVRFLHRSAEELPTTDDDGSYDAVFAAYLFRNVAEPGEVLRAVRALLRPGGRLL 149

Query: 147 LMFYNAHGLLMHNMV 161
              Y+  G  +H  V
Sbjct: 150 AHEYSLSGSRVHRAV 164


>UniRef50_Q09E54 Putative uncharacterized protein n=1 Tax=Stigmatella aurantiaca
           DW4/3-1 RepID=Q09E54_STIAU
          Length = 262

 Score = 50.1 bits (118), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 2/96 (2%)

Query: 48  VLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVAS 107
           VLD G G+G  +I +A RG +V   D+S + I+ A + A+  GV D + F HC+  ++A+
Sbjct: 34  VLDVGCGDGSNSILLASRGARVTGIDISPRSIELATERAKLAGVQDRVVF-HCSPLELAT 92

Query: 108 HLETPVDLILFHAVL-EWVADPRSVLQTLWSVLRPG 142
             E   D+I    +L   + +   VL  L    +PG
Sbjct: 93  FPENTFDVIWGDGILHHLIPELEGVLNQLERWGKPG 128


>UniRef50_Q0RJM9 Putative methyltransferase n=1 Tax=Frankia alni ACN14a
           RepID=Q0RJM9_FRAAA
          Length = 213

 Score = 50.1 bits (118), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 43/117 (36%), Positives = 59/117 (50%), Gaps = 18/117 (15%)

Query: 36  RVLAEMGPQK-LRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDN 94
           R+L    PQ   RVLD G G G  A ++A+R  QV   D SA+MI++A+     +G   N
Sbjct: 12  RLLLRQLPQPGRRVLDVGCGAGAFAARLAQRSEQVDAVDRSAEMIEQAR-----RGTPRN 66

Query: 95  MQFIHCAAQDVASHLETPV-----DLILFHAVLEWVADPRSVLQTLWSVLRPGGVLS 146
              +HC   DV   L  P+     D I   + L  +  P + L  L + LRPGGVL+
Sbjct: 67  ---VHCVLADV---LADPLPGKDYDAIFSISALHHMPLPEA-LGVLAAALRPGGVLA 116


>UniRef50_Q033A8 SAM-dependent methyltransferase n=6 Tax=Firmicutes
           RepID=Q033A8_LACLS
          Length = 246

 Score = 50.1 bits (118), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 38/142 (26%), Positives = 72/142 (50%), Gaps = 12/142 (8%)

Query: 24  QLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAK 83
           QL   ++W+ L    AE+     ++LD G G G  A  +A+R + VI  + +++M+   +
Sbjct: 18  QLYYRMVWEQLS---AEISLTDKKILDFGSGFGWNANHLADR-NSVIAIEPNSEMVKNRQ 73

Query: 84  QAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRS-VLQTLWSVLRPG 142
           Q       +++ Q I     ++    +   DLI+ H V E+ +D R+ +L+    +L   
Sbjct: 74  Q-------TNHYQQITGGLSELRKFNDEGFDLIICHNVFEYASDERAEILREFDRLLSKN 126

Query: 143 GVLSLMFYNAHGLLMHNMVAGN 164
           G++S++ +N  G LM  +V  N
Sbjct: 127 GLISIVKHNYAGALMQKIVFEN 148


>UniRef50_B3QY97 Methyltransferase type 11 n=1 Tax=Chloroherpeton thalassium ATCC
           35110 RepID=B3QY97_CHLT3
          Length = 213

 Score = 50.1 bits (118), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 36/108 (33%), Positives = 53/108 (49%), Gaps = 4/108 (3%)

Query: 35  DRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDN 94
           DRV   + P   +VLD G G G  +IKMA RG QV   D+S +MI  AK+      +  N
Sbjct: 31  DRVFDVLKPGA-KVLDIGCGTGNFSIKMARRGFQVTGVDISGEMISVAKKRLMETRLP-N 88

Query: 95  MQFIHCAAQDVASHLETPVDLILFHAVLEWVADPR--SVLQTLWSVLR 140
           +QF+H     +   L    D  +    +  +A P   +++Q+L  V R
Sbjct: 89  LQFLHINGVYLPDELNEHYDAAILSFSIHEMAPPERLALIQSLKKVAR 136


>UniRef50_B5JEA6 Methyltransferase domain family n=1 Tax=Verrucomicrobiae bacterium
           DG1235 RepID=B5JEA6_9BACT
          Length = 269

 Score = 50.1 bits (118), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 64/275 (23%), Positives = 110/275 (40%), Gaps = 55/275 (20%)

Query: 11  EKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQK-LRVLDAGGGEGQTAIKMAERGHQV 69
           E +SR   G  +G    A++ + +D +LAE   +     LD G G G TA   +E G + 
Sbjct: 16  ETWSRCASGYIEG--FGALVAEAIDSILAEASVKNGTFCLDVGTGPGNTAKSASELGART 73

Query: 70  ILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPR 129
           I  D S  M+      AEA+  +  ++F++ +A+ +    +   D ++ + +L    +P 
Sbjct: 74  IGIDFSDTML------AEARVRNPELEFLNASAEKLP-FADDEFDAVVGNYILHHSGEPE 126

Query: 130 SVLQTLWSVLRPGGVLSL-------------MFYNAHGL------LMHNMVAG--NFDYV 168
            +L   + VL+PGG  +              +F+ A G       L H  + G  +FD+ 
Sbjct: 127 KILSDSFRVLKPGGKAAFTVWSKPEKLEAFGLFFGAVGEHLGSPDLPHGPLFGISDFDHF 186

Query: 169 -----QAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDY----LREKH 219
                +AG  K   R L   +       YL               R FHD+    + +K 
Sbjct: 187 HHLLREAGFTKTSVRELPTVWKTPSISSYL---------------RAFHDWANLNVVDKE 231

Query: 220 QQRDCYEALLELETRYCRQEPYITLGRYIHVTARK 254
            +    E +L+   RY  +  Y      I ++  K
Sbjct: 232 IREKIEETILKSSGRYQSEGVYYIPNPSILLSGTK 266


>UniRef50_B2WBS7 Methyltransferase UbiE n=2 Tax=Pleosporineae RepID=B2WBS7_PYRTR
          Length = 274

 Score = 49.7 bits (117), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 35/119 (29%), Positives = 64/119 (53%), Gaps = 12/119 (10%)

Query: 37  VLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQ--VILCDLSAQMIDRAKQAAEAKGVSDN 94
           +L  +    L++LD G G G  ++ +A R  Q  V   D SA++I++A++ AE KGV+ N
Sbjct: 29  LLPYLSNPSLKILDVGCGPGTISVDLATRVPQGFVYAIDPSAEVIEKARKHAEEKGVT-N 87

Query: 95  MQFIHCAAQDV------ASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSL 147
           ++F      D+          E   D++  H VL+ + DP   ++ +  + +PGG+L++
Sbjct: 88  VRF---EVGDIFEWNKLVGLEEAGFDVVHAHQVLQHLQDPLGAMKAMKRLAKPGGLLAI 143


>UniRef50_B3QZ54 Magnesium protoporphyrin O-methyltransferase n=6 Tax=Chlorobiaceae
           RepID=B3QZ54_CHLT3
          Length = 233

 Score = 49.7 bits (117), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 23/55 (41%), Positives = 37/55 (67%)

Query: 43  PQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQF 97
           P+   +LDAG G G  +I +A+RG  V   D++AQM+++AK  A+ +GV+D + F
Sbjct: 64  PKGATILDAGCGTGLFSIAIAKRGFNVTAIDIAAQMVEQAKVDAKREGVADRINF 118


>UniRef50_C7JGN3 Biotin synthesis protein n=8 Tax=Acetobacter pasteurianus
           RepID=C7JGN3_ACEP3
          Length = 465

 Score = 49.7 bits (117), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 46/180 (25%), Positives = 80/180 (44%), Gaps = 24/180 (13%)

Query: 8   DIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTA--IKMAER 65
           D AEK+ +     T  ++    L+Q +   +A  G + LR+L+ G G G     ++    
Sbjct: 15  DAAEKYDQ---AATVQRVAARELFQRIHTCMA--GKKPLRILEIGCGTGLLTEHLRACWP 69

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV 125
              ++  D +  M+ RAK      G S +   +  A  DV      P DLI  + +++W+
Sbjct: 70  DADILATDFAPNMLARAKSRL---GESVSYHQMDAATPDV----NGPFDLICGNLIMQWL 122

Query: 126 ADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYP 185
            +P   L+TL  +L PGGVL+          +  ++ G F   Q    ++ +   +P YP
Sbjct: 123 PEPAKALRTLAEILAPGGVLA----------VSTLLDGTFAEWQQACAQEGQHAATPVYP 172


>UniRef50_C0ZBF0 Putative uncharacterized protein n=1 Tax=Brevibacillus brevis NBRC
           100599 RepID=C0ZBF0_BREBN
          Length = 245

 Score = 49.7 bits (117), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 50/192 (26%), Positives = 90/192 (46%), Gaps = 24/192 (12%)

Query: 47  RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA 106
           RVLD   G G+ +  +A RG++V+  DLS  ++    Q AE +     + F  C  +D+ 
Sbjct: 44  RVLDLCCGSGRHSRALARRGYEVVGVDLSPVLL----QLAEEQNTYPQLSFARCDMRDIP 99

Query: 107 SHLETPVDLILFHAVLEWVADPR--SVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGN 164
              E  + + LF +   +  D    +V++ +   L+  G + + F NA   ++ N+V  +
Sbjct: 100 FREEFDIVVNLFTSFGYFSTDEENANVIRNMAQALKTKGEVVIDFLNA-AYVIDNLVPHS 158

Query: 165 FDYVQAGMPKK---------KKRTL----SPDYPRD-PAQVYLWLEEAGWQIMGKTG--- 207
              V   + K+         KKR L    S + PR+   QV L+  E    ++ + G   
Sbjct: 159 TKEVSGMLIKEERWIQDGFVKKRILISDESSNEPREYMEQVRLFSAEQMIAMLTEAGFEK 218

Query: 208 VRVFHDYLREKH 219
           ++VF +YL E++
Sbjct: 219 IQVFGNYLFEEY 230


>UniRef50_C5FIU1 Cyclopropane-fatty-acyl-phospholipid synthase n=1 Tax=Microsporum
           canis CBS 113480 RepID=C5FIU1_NANOT
          Length = 277

 Score = 49.7 bits (117), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 30/99 (30%), Positives = 45/99 (45%)

Query: 47  RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA 106
           RVLDAG G G  A+ MA++G  V   DL    ++ AKQ  +   + D +        ++ 
Sbjct: 73  RVLDAGAGSGFVAMYMAKKGLNVDAIDLLPFHVEDAKQNVKQYDLEDKVAVSLADYHNLT 132

Query: 107 SHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVL 145
              +   D +          D   VLQ  + +L+PGGVL
Sbjct: 133 QFADNSFDGVYTMETFVHADDNMRVLQNFYRILKPGGVL 171


>UniRef50_UPI0001788486 Methyltransferase type 11 n=1 Tax=Geobacillus sp. Y412MC10
           RepID=UPI0001788486
          Length = 240

 Score = 49.7 bits (117), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 35/101 (34%), Positives = 55/101 (54%), Gaps = 8/101 (7%)

Query: 47  RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA 106
           R+L+ G G G+TA  ++E G+QV   DL+  MI +A+  AEA G+  +++F+     DV 
Sbjct: 37  RILEVGCGTGRTACHLSEMGYQVTAIDLNENMIKKARARAEAMGM--DVEFLQA---DVC 91

Query: 107 S--HLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVL 145
           +    +   DLI+  +V  +  D    L   + VL  GGVL
Sbjct: 92  ALPFEDNRFDLIMAESVTVFT-DTSKSLPEYYRVLDRGGVL 131


>UniRef50_A6CF73 Methyltransferase type 11 n=1 Tax=Planctomyces maris DSM 8797
           RepID=A6CF73_9PLAN
          Length = 228

 Score = 49.7 bits (117), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 41/148 (27%), Positives = 69/148 (46%), Gaps = 18/148 (12%)

Query: 48  VLDAGGGEGQTAIKMAERGH---QVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQD 104
           +LD G G GQ    +    H   +++ CDLS QM+ RA+   +    S    ++     +
Sbjct: 61  ILDIGSGAGQILGHLLRETHPDARLVACDLSHQMLKRARVRMD----SPRPNYLSADMTN 116

Query: 105 VASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFY--NAHGLL------ 156
           +    E+  D +    VLE+VADPR  L  +  VL+PGG L L+       G+L      
Sbjct: 117 LPFQDES-FDCVTCGWVLEYVADPRHGLTEIHRVLQPGGSLFLLATEDKFSGMLNSRTWK 175

Query: 157 --MHNMVAGNFDYVQAGMPKKKKRTLSP 182
              +N +     + ++G+P K++   +P
Sbjct: 176 CRTYNRIELKQAFEESGLPWKEQHWFTP 203


>UniRef50_A5ZYR5 Putative uncharacterized protein (Fragment) n=1 Tax=Ruminococcus
           obeum ATCC 29174 RepID=A5ZYR5_9FIRM
          Length = 796

 Score = 49.7 bits (117), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 39/123 (31%), Positives = 61/123 (49%), Gaps = 12/123 (9%)

Query: 30  LWQD-----LDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQ 84
           +W+D     L     E  P ++++LD G G G  AI +AE G+QV   D + +M+  A+Q
Sbjct: 34  MWRDKLLSLLGEAFPEREPGEIKILDVGTGPGFFAILLAEAGYQVTAVDYTEEMLREAQQ 93

Query: 85  AAEAKGVSDNMQFIHCAAQ--DVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPG 142
              A G+++ + +    AQ  DV S+     D I+   V   +  P    +    VL+PG
Sbjct: 94  --NAGGLAECIVWKTGDAQALDVESN---SFDAIVTRNVTWNLPRPDLAYKEWLRVLKPG 148

Query: 143 GVL 145
           GVL
Sbjct: 149 GVL 151



 Score = 48.1 bits (113), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 38/112 (33%), Positives = 57/112 (50%), Gaps = 4/112 (3%)

Query: 44  QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQ 103
           +KLR+LD G G G   I +A+ GHQV   DL+  MI  A+  A+ +G   + +F    A+
Sbjct: 624 KKLRILDVGCGAGFFTILLAKAGHQVTGIDLTPDMIKNARILAQEEGA--DCEFTVMDAE 681

Query: 104 DVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGL 155
           +     +T  D+I+   +   +   R   Q    VLR GGVL L F   +G+
Sbjct: 682 NPEFPDDT-FDVIISRNLTWTLPHVRHAYQEWLRVLRKGGVL-LNFDANYGI 731


>UniRef50_A4EUG7 Methyltransferase, UbiE/COQ5 family protein n=5 Tax=Rhodobacterales
           RepID=A4EUG7_9RHOB
          Length = 211

 Score = 49.7 bits (117), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 39/141 (27%), Positives = 71/141 (50%), Gaps = 13/141 (9%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQ-DLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
           +D+IA K++       K  +R    ++  L R  + + P   RVL+ G G   TAI++A+
Sbjct: 8   WDNIAPKYA-------KSSIRDEESYRYALGRTRSYLKPND-RVLELGCGTASTAIELAK 59

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
                +  D+S  M+   +Q A+  G +DN+  +H  A+D+A   +   D +L H +L  
Sbjct: 60  GVESFVATDISDGMLAVGRQRAQEAG-ADNLTLLHRPAEDLA---DGEFDAVLAHNLLHL 115

Query: 125 VADPRSVLQTLWSVLRPGGVL 145
           + +   VL+ + + L  GG+ 
Sbjct: 116 IPNLEEVLRNVAAKLPTGGLF 136


>UniRef50_C5UZZ2 Methyltransferase type 11 n=1 Tax=Gallionella ferruginea ES-2
           RepID=C5UZZ2_9PROT
          Length = 881

 Score = 49.7 bits (117), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 34/107 (31%), Positives = 58/107 (54%), Gaps = 4/107 (3%)

Query: 47  RVLDAGGGEGQTAIKMAERGH--QVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQD 104
           R+L AG G GQ +I +A+R    Q++  DLS   +  AK+     G+S ++++      +
Sbjct: 639 RILIAGCGTGQHSISLAQRTRDAQILAIDLSTSSLAYAKRKTLELGIS-SIEYAQADLLE 697

Query: 105 VASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYN 151
           +A H +   ++I    VL  + DP +  Q L +VL+PGG + L  Y+
Sbjct: 698 IA-HDKRRFEMIQSSGVLHHMKDPWAGWQALLTVLKPGGFMKLGLYS 743


>UniRef50_A8TQ26 Tetratricopeptide TPR_4 n=1 Tax=alpha proteobacterium BAL199
           RepID=A8TQ26_9PROT
          Length = 636

 Score = 49.7 bits (117), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 43/136 (31%), Positives = 66/136 (48%), Gaps = 13/136 (9%)

Query: 42  GPQKLRVLDAGGGEGQTAIKMAERGHQ--VILCDLSAQMIDRAKQAAEAKGVSDNMQFIH 99
           GP  +R+L AG G G+ AI+ A R H   V+  DLS + +  AK+ A   GV DN+ F  
Sbjct: 394 GP--MRILIAGCGTGRHAIQTARRYHDSLVLAVDLSRRSLAYAKRMARDLGV-DNLTFGQ 450

Query: 100 CAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHN 159
                +    +   DLI    VL  ++DP +  + L  +L PGG++ +  Y+        
Sbjct: 451 ADILALGQRADR-FDLIESSGVLHHLSDPMAGWRVLRGLLAPGGLMRIALYS-------R 502

Query: 160 MVAGNFDYVQAGMPKK 175
                FD V+A +P +
Sbjct: 503 RARAGFDDVRAVVPAE 518


>UniRef50_O18235 Protein Y57G11C.11a, confirmed by transcript evidence n=3
           Tax=Caenorhabditis RepID=O18235_CAEEL
          Length = 268

 Score = 49.7 bits (117), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 32/112 (28%), Positives = 54/112 (48%), Gaps = 7/112 (6%)

Query: 47  RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAK-----GVSDNMQFIHCA 101
           R++D G G G  +I +A  G  V   D + Q ++ A Q+  AK     G+S  ++F H +
Sbjct: 78  RLVDVGSGGGLLSIPLARSGFDVTGIDATKQAVEAANQSLTAKPLQIAGISKRLRFEHTS 137

Query: 102 AQDVA--SHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYN 151
            +D     H ++  D ++   ++E VAD    +  L  + RPG  L +   N
Sbjct: 138 VEDFCQKPHNKSAYDAVVASEIVEHVADLPGFIGCLAELARPGAPLFITTIN 189


>UniRef50_P08442 Uncharacterized protein syc1184_c n=29 Tax=Cyanobacteria
           RepID=Y1184_SYNP6
          Length = 417

 Score = 49.7 bits (117), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 36/110 (32%), Positives = 52/110 (47%), Gaps = 3/110 (2%)

Query: 47  RVLDAGGGEGQTAIKMA--ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQD 104
           R+LDAG G G +   +A      ++   D+SA  +  A++  +  GV+D + F   +  D
Sbjct: 74  RILDAGCGTGVSTDYLAHLNPSAEITAIDISAGTLAVAQERCQRSGVADRIHFQQLSLYD 133

Query: 105 VASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHG 154
           VA  L    D I    VL  + DP   L  L S L PGG+L +  Y   G
Sbjct: 134 VA-QLPGEFDQINCVGVLHHLEDPDRGLAALASKLAPGGILHIFVYAEIG 182


>UniRef50_Q0G0C8 SAM (And some other nucleotide) binding motif:Generic
           methyltransferase:Bacterial regulatory protein, ArsR n=2
           Tax=Aurantimonadaceae RepID=Q0G0C8_9RHIZ
          Length = 337

 Score = 49.7 bits (117), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 39/121 (32%), Positives = 64/121 (52%), Gaps = 6/121 (4%)

Query: 34  LDRVLAEMGPQKL-RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVS 92
           LDRVL   G Q++  +LD G G G+    +A R  +++  D S +MI  A+   +   V 
Sbjct: 148 LDRVL---GKQRIGTMLDIGTGTGRMMEMLANRCERMLGVDTSREMISAARAKLDDAKVK 204

Query: 93  DNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNA 152
            N Q     A ++ ++ ET  DL++ H VL ++ +P   ++   SVL PGG L ++ +  
Sbjct: 205 -NAQLRVGDAYNLPANGET-YDLVVLHQVLHYLDEPMRAVREASSVLAPGGRLVIVDFAP 262

Query: 153 H 153
           H
Sbjct: 263 H 263


>UniRef50_Q2RJ99 UbiE/COQ5 methyltransferase n=1 Tax=Moorella thermoacetica ATCC
           39073 RepID=Q2RJ99_MOOTA
          Length = 230

 Score = 49.7 bits (117), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 32/108 (29%), Positives = 60/108 (55%), Gaps = 3/108 (2%)

Query: 48  VLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVAS 107
           +LD G G G  ++++A RG +V   D+S  M+ +A++ A   G++  ++F+H  A ++  
Sbjct: 44  ILDVGCGTGNFSLELARRGVKVTGIDISDPMLAKARKKAADAGLA--IEFLHADAMNLPF 101

Query: 108 HLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGL 155
              T  D I+    LE+  D ++VL+  + VL+PGG + +     + L
Sbjct: 102 GDNT-FDKIVSVTALEFAPDLKAVLEESYRVLKPGGRMVIGLIGGNSL 148


>UniRef50_Q9EYI2 SnogM n=1 Tax=Streptomyces nogalater RepID=Q9EYI2_STRNO
          Length = 278

 Score = 49.7 bits (117), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 38/112 (33%), Positives = 60/112 (53%), Gaps = 8/112 (7%)

Query: 40  EMGPQKLRVLDAGGGEGQTAIKMAE-RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFI 98
           E+GP + RVLD G G G  A+++A   G +V+   +S + +  A   AE +GV++ + F 
Sbjct: 60  EVGPGQ-RVLDIGCGTGAPAVQLARATGAEVVGITISPEQVRLATAHAEREGVAERVTF- 117

Query: 99  HCAAQDVASHLETPVD---LILFHAVLEWVADPRSVLQTLWSVLRPGGVLSL 147
            CA  D ++ L  P D    + F   +  + D  + L+    VLRPGG L+L
Sbjct: 118 RCA--DASAELPFPADSFDAVWFFESIFHLPDRLTALRRAAEVLRPGGRLAL 167


>UniRef50_Q1ITC0 Putative uncharacterized protein n=1 Tax=Candidatus Koribacter
           versatilis Ellin345 RepID=Q1ITC0_ACIBL
          Length = 271

 Score = 49.3 bits (116), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 34/150 (22%), Positives = 73/150 (48%), Gaps = 10/150 (6%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           FD IA ++      +  G+ ++A++W+++DR           VLD   G G+ A+ + +R
Sbjct: 14  FDGIANEYDELFTNSLIGRAQRAVVWREIDRTFQPGDT----VLDLNCGTGEDALYLVKR 69

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQF-IHCAAQDVASHLETPVD---LILFHAV 121
           G  V+ CD S +M++ A+   + +G+++  +   H  A +    L        ++   A 
Sbjct: 70  GINVVGCDASRRMVEVAQN--KLRGITNPARGEFHVLANEQLCELHASAKFQGVLSNFAG 127

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYN 151
           +   ++ R+V   + ++L PG +  +  Y+
Sbjct: 128 INCASELRNVAVQMSNILSPGAIAVICVYS 157


>UniRef50_C5S6C8 Methyltransferase type 11 n=1 Tax=Allochromatium vinosum DSM 180
           RepID=C5S6C8_CHRVI
          Length = 699

 Score = 49.3 bits (116), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 42/153 (27%), Positives = 74/153 (48%), Gaps = 17/153 (11%)

Query: 31  WQDLDRV---LAEMGPQKLRVLDAGGGEGQTAIKMAER-GHQVIL--CDLSAQMIDRAKQ 84
           W   DRV   +A + P+  RV+D G G G  + ++AE  G + ++   D     + + K 
Sbjct: 176 WDATDRVVEIIAGLEPKVRRVIDLGAGFGYFSTRIAEALGPEAVVYAADTEEAYVAQLKT 235

Query: 85  AAEAKGVSDNMQFIHCAAQDVASHLETPVDLI----LFHAVLEWV--ADPRSVLQTLWSV 138
             +  G+ D ++ +H    D+   +  P DL+    L+H +  W    +  + ++TL   
Sbjct: 236 FVDQSGI-DGVRPVHSKPNDIV--VRDPTDLVFISSLYHVLYAWSQPTERDAFMETLNQT 292

Query: 139 LRPGGVLSLMFYNAH-GLLMHNMVAGNFDYVQA 170
           LRPGG L ++    H G  +HN    + ++VQA
Sbjct: 293 LRPGGYLVVLDNRDHDGASLHNAYV-DREFVQA 324


>UniRef50_Q8D299 BioC protein n=1 Tax=Wigglesworthia glossinidia endosymbiont of
           Glossina brevipalpis RepID=Q8D299_WIGBR
          Length = 253

 Score = 49.3 bits (116), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 30/101 (29%), Positives = 51/101 (50%), Gaps = 7/101 (6%)

Query: 47  RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA 106
           ++LDAG G G  +       +QVI  D+S  M+++AK+   A     N+  +     + +
Sbjct: 46  KLLDAGCGTGLFSRYWKSFNNQVIALDISYGMLEQAKRRNSA-----NIYIL--GDIENS 98

Query: 107 SHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSL 147
             ++  VD+I  +  ++W  D    L  L+ +LRPGG L L
Sbjct: 99  PLIDKTVDIIFSNLAIQWCNDFSRALSELYRILRPGGFLVL 139


>UniRef50_B5YA44 Putative methyl transferase n=2 Tax=Firmicutes RepID=B5YA44_COPPD
          Length = 287

 Score = 49.3 bits (116), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 36/136 (26%), Positives = 67/136 (49%), Gaps = 10/136 (7%)

Query: 31  WQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVIL-CDLSAQMIDRAKQAAEAK 89
           + DLD++  +       VLD G G     +  A  G + I   D   +  ++A++ A++K
Sbjct: 51  FTDLDQLFKDK-----TVLDIGCGAAGKTVFYATCGVKEIYGVDKVEKYKEQAERLAKSK 105

Query: 90  GVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVL---S 146
           GV D   F+   A  +    E   D I+ +  +E  + P++VL   + VL+PGG+L   S
Sbjct: 106 GVEDKFHFVIADAATLPFS-ENTFDTIIMNDFMEHASQPQNVLLECYRVLKPGGMLYVNS 164

Query: 147 LMFYNAHGLLMHNMVA 162
             +Y+ +G  + +++ 
Sbjct: 165 PPYYHPYGAHLSDLIG 180


>UniRef50_A3UCE4 Methyltransferase, UbiE/COQ5 family protein n=1 Tax=Oceanicaulis
           alexandrii HTCC2633 RepID=A3UCE4_9RHOB
          Length = 208

 Score = 49.3 bits (116), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 45/145 (31%), Positives = 73/145 (50%), Gaps = 10/145 (6%)

Query: 2   QDRNF-DDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           QD+ F D IA K++++          Q      L++  A   P+  RVL+ G G G TAI
Sbjct: 3   QDKAFWDRIARKYAQDPIAD------QTSYEHKLEKTRAHFTPES-RVLEYGCGTGSTAI 55

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
             A    +++  DLS +MI  A++ A   GV +N++F      D+    E+  D++L   
Sbjct: 56  LHAPHVREIVATDLSDEMIAIARERAAEAGV-NNIRFEATDVADLHERDES-FDVVLALN 113

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVL 145
           VL  V D ++ ++    +L+PGGV 
Sbjct: 114 VLHLVPDRQAAMRLSRDLLKPGGVF 138


>UniRef50_Q0W229 Putative uncharacterized protein n=1 Tax=uncultured methanogenic
           archaeon RC-I RepID=Q0W229_UNCMA
          Length = 253

 Score = 49.3 bits (116), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 36/104 (34%), Positives = 52/104 (50%), Gaps = 8/104 (7%)

Query: 47  RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA 106
           RVLD G G G+TA  +A+ G   I+ DL A ++ +A+  A   G S+ + FI    Q   
Sbjct: 44  RVLDMGCGAGRTADMLAKSGVSPIVVDLDAGVLIKARALATRSGTSEKLSFI----QADL 99

Query: 107 SHL---ETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSL 147
            HL   E   D  L  +VL +  D   V++  + VL+PGG    
Sbjct: 100 HHLPFKEGTFDAALAESVLAYC-DAAHVVRESYRVLKPGGAFGF 142


>UniRef50_A5CQB8 Putative methyltransferase n=2 Tax=Clavibacter michiganensis
           RepID=A5CQB8_CLAM3
          Length = 285

 Score = 49.3 bits (116), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 35/103 (33%), Positives = 53/103 (51%), Gaps = 3/103 (2%)

Query: 48  VLDAGGGEGQTAIKMAER--GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDV 105
           V+D G G G   + +A R    +V   D SA M+DR  + A   G++D ++ +H A  D 
Sbjct: 49  VVDLGAGTGTGTVALAWRFDRAEVHAVDASAAMLDRVTERAFVDGLADRIRTVH-ADLDA 107

Query: 106 ASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLM 148
                 P DL+    VL  VADP  +L  +   L PGG+L+++
Sbjct: 108 DWPALPPADLVWASLVLHEVADPAGLLARVHDGLAPGGLLAVV 150


>UniRef50_C8VZ57 Methyltransferase type 11 n=1 Tax=Desulfotomaculum acetoxidans DSM
           771 RepID=C8VZ57_DESAS
          Length = 240

 Score = 49.3 bits (116), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 41/153 (26%), Positives = 67/153 (43%), Gaps = 11/153 (7%)

Query: 2   QDRNFDDIAEKF---SRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQT 58
            +  FDDIA K+   ++   G    +L     ++    + A   P    VLD G G G  
Sbjct: 6   SNPTFDDIAAKYDLWAKLPLGKLCAKLENEAFFKAYGDI-AGSDP----VLDIGCGTGNY 60

Query: 59  AIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILF 118
            I +A  G  V   D S  M+  A+Q    +G   ++  +H  A+++    E     ++ 
Sbjct: 61  IINLAGCGLDVTGLDASENMLAVARQKLTKQGFQASL--VHSLAENIPFK-EHSFKTVIC 117

Query: 119 HAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYN 151
              LE++  P  V+Q ++ VL+P G   L F N
Sbjct: 118 SLALEFMGRPEKVVQEIFRVLQPSGQFILAFLN 150


>UniRef50_D2B333 Methyltransferase type 11 n=4 Tax=Actinomycetales
           RepID=D2B333_STRRD
          Length = 281

 Score = 49.3 bits (116), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 48/168 (28%), Positives = 76/168 (45%), Gaps = 15/168 (8%)

Query: 44  QKLRVLDAGGGEGQT---AIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHC 100
           ++ RVLD G G GQ    A + A  GH   + DLSA M+ RA+  A  +GV+ N+ F   
Sbjct: 47  ERDRVLDVGCGNGQVTRLAARRARLGHTTGI-DLSAPMLRRARACAADEGVA-NVTFERG 104

Query: 101 AAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSL-----MFYNAHGL 155
            AQ +    +   D+ +    + + ADP +    +   LRPGG L+      M  N  G 
Sbjct: 105 DAQ-IHPFPDAGFDVAVSRFGIMFFADPVAAFANIGRALRPGGRLAFLSLREMGDNDLGP 163

Query: 156 LMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIM 203
           ++  M     D++ A           P+   DP ++   L  AG++ +
Sbjct: 164 VLTAMA----DHLPARPATTGPGAPGPESLADPGRIREVLTGAGFEAV 207


>UniRef50_Q9RX93 Trans-aconitate 2-methyltransferase n=2 Tax=Deinococci
           RepID=TAM_DEIRA
          Length = 258

 Score = 49.3 bits (116), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 33/118 (27%), Positives = 56/118 (47%), Gaps = 7/118 (5%)

Query: 47  RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA 106
           +V+D G G G+   ++A+R  Q  +  L +     AK  A+      N++F     Q+++
Sbjct: 33  QVVDLGCGTGEQTAQLAQRFPQATVLGLDSSAAMLAKAGAQQL---PNLRFEQGDIQELS 89

Query: 107 SHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGN 164
                  DL+  +A L+W+ D   +L  LW  LRPGGVL++     H    H ++   
Sbjct: 90  GSF----DLLYSNAALQWLPDHPRLLARLWEHLRPGGVLAVQVPANHDHASHRLLTAT 143


>UniRef50_Q9RYC4 Methyltransferase, putative n=2 Tax=Deinococcus RepID=Q9RYC4_DEIRA
          Length = 269

 Score = 49.3 bits (116), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 35/114 (30%), Positives = 59/114 (51%), Gaps = 5/114 (4%)

Query: 43  PQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAA 102
           P   RVLD   G G  A+ +A +  +V+  D++  MI++A+Q A  +    N+QF+   A
Sbjct: 42  PPTGRVLDVATGTGTVALTLAPKVAEVMGTDIAPAMIEQARQRAAGR---SNVQFVLAEA 98

Query: 103 QDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLL 156
             + +  +   D+++  A L +V D  + L+    VLRPGG +    +   GLL
Sbjct: 99  TAL-TFADQSFDVVVCGAGLFFVPDMVAALREWRRVLRPGGEVVFSAFG-RGLL 150


>UniRef50_B4UHL7 Methyltransferase type 11 n=41 Tax=Bacteria RepID=B4UHL7_ANASK
          Length = 269

 Score = 48.9 bits (115), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 41/146 (28%), Positives = 69/146 (47%), Gaps = 8/146 (5%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M +  +DD     + +    + G L +A  W     +L ++  +  RVLD G G G    
Sbjct: 1   MAENRYDDAVVFTNYSQLARSVGGLAEAGEWSAFRALLPDL--RGKRVLDLGCGFGWHCR 58

Query: 61  KMAERGHQVIL-CDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFH 119
              E+G   ++  D+S +M++RA+    A G    + ++  A +DV     T  D+++  
Sbjct: 59  HALEQGASAVVGVDVSEKMLERAR----ALGSDARLTYVRSAIEDVELAPAT-FDVVISS 113

Query: 120 AVLEWVADPRSVLQTLWSVLRPGGVL 145
             L +VAD   VL  + + LRPGG L
Sbjct: 114 LALHYVADLAKVLANVRACLRPGGAL 139


>UniRef50_B8FTI1 Methyltransferase type 11 n=2 Tax=Desulfitobacterium hafniense
           RepID=B8FTI1_DESHD
          Length = 301

 Score = 48.9 bits (115), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 32/100 (32%), Positives = 59/100 (59%), Gaps = 3/100 (3%)

Query: 48  VLDAGGGEGQTAIKMAE-RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA 106
           +LDAG G G TA  +A+ +G ++I  D+++QMI++A+Q AE +GV+  ++F   A  +  
Sbjct: 55  ILDAGCGSGLTACYLAKNKGCKIIGVDINSQMIEKARQRAEHEGVAHLVEF-RVADVNRL 113

Query: 107 SHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLS 146
              +   D I+  ++  ++ D   V Q  + VL+P G ++
Sbjct: 114 PFPDDHFDWIMCESITVFL-DKGKVYQEFFRVLKPEGRIA 152


>UniRef50_Q465A0 Putative uncharacterized protein n=2 Tax=Methanosarcina
           RepID=Q465A0_METBF
          Length = 244

 Score = 48.9 bits (115), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 34/133 (25%), Positives = 64/133 (48%), Gaps = 7/133 (5%)

Query: 44  QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQ 103
           +K+R ++ G G G  AI +A  GH V   DLS  M+++A + A+ KGV  ++  +   A+
Sbjct: 49  KKIRAVEVGTGPGLLAISLAAMGHDVTGVDLSENMLEKAAENAKEKGV--DVSLVQGDAE 106

Query: 104 DVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVL----SLMFYNAHGLLMHN 159
            +  + +   D +L   +L  +  P   +     +L+ GG++     L F N  G    +
Sbjct: 107 KIPLN-DGEYDFVLSKYLLWTLPQPDKFMSECCRLLKDGGLMMIVDGLWFQNPDGTEKKS 165

Query: 160 MVAGNFDYVQAGM 172
                F+ + +G+
Sbjct: 166 SRYEKFNELYSGV 178


>UniRef50_B5JNH0 Methyltransferase domain family n=1 Tax=Verrucomicrobiae bacterium
           DG1235 RepID=B5JNH0_9BACT
          Length = 263

 Score = 48.9 bits (115), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 36/99 (36%), Positives = 51/99 (51%), Gaps = 2/99 (2%)

Query: 47  RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA 106
           +VLD   G G  +  +A  G QV   DLS   I+ AK+ A  +G+S N +F+   A+  +
Sbjct: 66  KVLDYCCGAGGNSRFVAACGAQVTGIDLSDSEIETAKRLANEEGLSKNTEFVVMDAEKTS 125

Query: 107 SHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVL 145
              ET  D+I+   VL  V D     + L  VL+PGG L
Sbjct: 126 FENET-FDMIICSGVLHHV-DLDVAYKELNRVLKPGGKL 162


>UniRef50_UPI000186D07C hexaprenyldihydroxybenzoate methyltransferase, putative n=1
           Tax=Pediculus humanus corporis RepID=UPI000186D07C
          Length = 281

 Score = 48.9 bits (115), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 37/131 (28%), Positives = 65/131 (49%), Gaps = 4/131 (3%)

Query: 25  LRQAILWQDLDRVLAEMGPQKL---RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDR 81
           +R  +++     V    GP+ L   ++LD G G G  +  +A  G  V   D   ++ID 
Sbjct: 71  VRDGLMYTKKADVENPNGPRPLNGVKILDVGCGGGILSEPLARIGADVTGIDPGQKLIDI 130

Query: 82  AK-QAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLR 140
           AK  AAE   VS  ++++  + +D A+  +   D ++   V+E VA     L++  +VL+
Sbjct: 131 AKTHAAEDPTVSGKIRYLCESIEDHANGHKEKYDAVVASEVIEHVASKEIFLESCANVLK 190

Query: 141 PGGVLSLMFYN 151
           PGG + +   N
Sbjct: 191 PGGSIFITTIN 201


>UniRef50_Q47PB3 S-adenosylmethionine (SAM)-dependent methyltransferase n=1
           Tax=Thermobifida fusca YX RepID=Q47PB3_THEFY
          Length = 251

 Score = 48.9 bits (115), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 49/156 (31%), Positives = 71/156 (45%), Gaps = 13/156 (8%)

Query: 47  RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA 106
           RVLDAG G G    ++A  G  V+  D+S +M+ RA  AA   G+   +  +       A
Sbjct: 36  RVLDAGCGTGDHVAQLAAAGVDVLGVDISPEMVARA--AARFPGIPVTVADLR------A 87

Query: 107 SHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFD 166
                  D +L +AVL WV +      +L +VLRPGG L      A G +     A +  
Sbjct: 88  LPFREEFDAVLSNAVLHWVPEADQAAASLRAVLRPGGRLVAELGGA-GNIATLTTAIHEL 146

Query: 167 YVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQI 202
             + G+P+      SP Y    AQ    LE AG+++
Sbjct: 147 RAEWGLPQAA----SPWYFPTVAQYARVLENAGFEV 178


>UniRef50_B8DK00 Methyltransferase type 11 n=1 Tax=Desulfovibrio vulgaris str.
           'Miyazaki F' RepID=B8DK00_DESVM
          Length = 307

 Score = 48.9 bits (115), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 46/135 (34%), Positives = 61/135 (45%), Gaps = 11/135 (8%)

Query: 15  RNIYGTTKGQLRQAILWQDLD--RVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILC 72
           R + G T      A+ W+ L+  R L  M P   RVLD G G G+T   + E G   +  
Sbjct: 54  RAVAGATLRPGGVALTWRALELARQL-TMWPHNARVLDLGCGPGETVALLREGGMAAVGL 112

Query: 73  DLSAQMIDRAKQAAEAKGVSDNMQFIH-CAAQDVASHLET-PVDLILFHAVLEWVADPRS 130
           D+SA ++      AEA   +  M  I  CA       L T  +D +    VL  +   + 
Sbjct: 113 DISASLL------AEALARNGRMPLIRACAGAAPGLPLRTASLDGVFCECVLSVLPQQQG 166

Query: 131 VLQTLWSVLRPGGVL 145
           VL  L  VLRPGGVL
Sbjct: 167 VLAELARVLRPGGVL 181


>UniRef50_Q0YPN2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase:UbiE/COQ5
           methyltransferase n=1 Tax=Chlorobium ferrooxidans DSM
           13031 RepID=Q0YPN2_9CHLB
          Length = 275

 Score = 48.9 bits (115), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 35/102 (34%), Positives = 54/102 (52%), Gaps = 7/102 (6%)

Query: 48  VLDAGGGEGQTAI----KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQ 103
           VLD G G G  A     K+ ERG +VI  D++ +MI+RA+  A   G   N++F     +
Sbjct: 80  VLDLGSGAGVDAFLASNKVGERG-RVIGVDMTPEMIERARVNARNNGYR-NVEFRQGEIE 137

Query: 104 DVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVL 145
           ++     + VD+I+ + V+    D   V Q  + VL+PGG L
Sbjct: 138 NLPIE-SSSVDVIISNCVINLSTDKPKVFQEAFRVLKPGGSL 178


>UniRef50_B6GZM9 Pc12g02220 protein n=13 Tax=Eurotiomycetidae RepID=B6GZM9_PENCW
          Length = 278

 Score = 48.9 bits (115), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 42/173 (24%), Positives = 78/173 (45%), Gaps = 9/173 (5%)

Query: 36  RVLAEMGPQKL-RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDN 94
           ++LA + P+   +VLD G G+G+           V+  D SA MI+ A +   +   +  
Sbjct: 32  KLLASLDPKPTDKVLDVGCGDGKFTANFLPAIDSVLGIDSSASMIESANEDYGSSKAT-- 89

Query: 95  MQFIHCA-AQDVASHLETPVDLILFHAVLEWV----ADPRSVLQTLWSVLRPGGVLSLMF 149
            + + C   +   S +    D ++ +A L W+    +   S L+ ++  L+PGG   +  
Sbjct: 90  FRVVDCRYLEKETSIVNGSWDKVISNAALHWILRDESTRMSTLRAIYGCLKPGGTY-VFE 148

Query: 150 YNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQI 202
              HG +     A  +  VQ G+P ++ R  SP +      +   LEE G+++
Sbjct: 149 MGGHGNIAEVKTALVYAVVQQGIPIEQARETSPWFFPSDTWMRNALEEIGFKV 201


>UniRef50_Q46JP9 TPR repeat n=2 Tax=Prochlorococcus marinus RepID=Q46JP9_PROMT
          Length = 779

 Score = 48.9 bits (115), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 34/117 (29%), Positives = 55/117 (47%), Gaps = 3/117 (2%)

Query: 39  AEMGPQKLRVLDAGGGEGQTAIKMAERGH-QVILCDLSAQMIDRAKQAAEAKGVSDNMQF 97
            ++  +K+ +L AG G G   I+ +   + ++   DLS   I  AK+  +  G+  N+ F
Sbjct: 531 VQLTNKKINILIAGCGTGIQIIEASRYSNCEITAIDLSNSSISYAKRKVDEYGLK-NINF 589

Query: 98  IHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHG 154
           I     ++ S L    DLI    VL  + +P   L  L+ VL P G L L  Y+ + 
Sbjct: 590 IEMDLLELTS-LNKRFDLIECSGVLHHMNEPSKGLSNLFDVLEPEGFLKLGLYSKYA 645


>UniRef50_C7MVS3 Methylase of polypeptide chain release factors n=1
           Tax=Saccharomonospora viridis DSM 43017
           RepID=C7MVS3_SACVD
          Length = 227

 Score = 48.9 bits (115), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 35/131 (26%), Positives = 59/131 (45%), Gaps = 12/131 (9%)

Query: 47  RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA 106
           RVLD G G G  A+  A     V+  D++ + ++ A+  A    V+D ++  H    DV 
Sbjct: 64  RVLDMGTGSGVNAVLAAAEAESVLAVDINPKALEAARDNARRNDVADRIEVRHS---DVF 120

Query: 107 SHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHN------- 159
           S ++   DLI+F     W   PR+V ++  +     G ++  F  A   L  N       
Sbjct: 121 SDVDGRFDLIVFDPPFRWFR-PRTVFESAMTD-ENYGAMTRFFLGARDHLTDNGRMLIFF 178

Query: 160 MVAGNFDYVQA 170
             +G+ DY+ +
Sbjct: 179 GTSGDLDYLTS 189


>UniRef50_B6IPG3 Trans-aconitate 2-methyltransferase n=1 Tax=Rhodospirillum centenum
           SW RepID=B6IPG3_RHOCS
          Length = 257

 Score = 48.9 bits (115), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 51/171 (29%), Positives = 77/171 (45%), Gaps = 30/171 (17%)

Query: 37  VLAEMGP-QKLRVLDAGGGEGQTAIKMAER--GHQVILCDLSAQMIDRAKQAAEAKGVSD 93
           ++A + P +  R++D G G G+  +++A R  G  V+  D S +M+  A QA       D
Sbjct: 22  LMAALPPVRPARIVDLGCGSGRLTVELAARHPGASVVGLDNSPEMLADAPQA-------D 74

Query: 94  NMQFIHCAAQDVAS-HLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFY-- 150
               I     D+A+ +   PVDLI  +A L W+ D  ++   L + L PGGVL++     
Sbjct: 75  GR--IAWQPGDIAAWNPADPVDLIFSNAALHWLDDHATLFPRLVARLAPGGVLAVQMPVT 132

Query: 151 ---NAHGLLMHNMVAGNFDYVQAGMPKKKKRT---LSPDYPRDPAQVYLWL 195
                   L+H +         AG P    R    L PD  R PA  + WL
Sbjct: 133 DPEAPFRALLHRL---------AGQPPWAARLAGRLRPDAVRPPAAYHRWL 174


>UniRef50_C7PGL9 Methyltransferase type 11 n=2 Tax=Sphingobacteriales
           RepID=C7PGL9_CHIPD
          Length = 203

 Score = 48.9 bits (115), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 37/137 (27%), Positives = 65/137 (47%), Gaps = 8/137 (5%)

Query: 48  VLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQ-AAEAKGVSDNMQFIHCAAQDVA 106
           VLDAG G G+  I   + G+ V   D +   ++  +Q +A     +    F+  +A+++ 
Sbjct: 31  VLDAGCGGGRNLIYFLKNGYDVYGIDPNPNAVEAVRQLSATLSHTNATENFVVASAENLP 90

Query: 107 SHLETPVDLILFHAVLEWVADP---RSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAG 163
              +   DLI+  AVL +  DP   + ++ ++W VL+PGG L     +  G+       G
Sbjct: 91  FE-DNTFDLIISSAVLHFAQDPAHFQDMIYSMWRVLKPGGYLFARLASDIGIETQVQDLG 149

Query: 164 NFDYVQAGMPKKKKRTL 180
           N  Y+   +P   +R L
Sbjct: 150 NGRYL---LPDGSERFL 163


>UniRef50_Q4C8V0 Similar to Methylase involved in ubiquinone/menaquinone
           biosynthesis n=1 Tax=Crocosphaera watsonii WH 8501
           RepID=Q4C8V0_CROWT
          Length = 229

 Score = 48.9 bits (115), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 44/159 (27%), Positives = 77/159 (48%), Gaps = 14/159 (8%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQK-LRVLDAGGGEGQTAIKMAE 64
           F++ A K+ +   G TKG + +       D +  E+   K  R+LD G G G+ +I++A+
Sbjct: 9   FENYALKYDQE--GFTKGTVGEC------DFLEEEINYDKNTRILDIGCGTGRHSIELAK 60

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
           RG+QV+  DLS  +++RAK     + +S  ++F    A+++    E  +  I+       
Sbjct: 61  RGYQVVGIDLSDSLLNRAKDKVLGENLS--LEFYKHDARNLPFIDEFDLVYIMCEGGFCL 118

Query: 125 VADPRSVLQTLWS---VLRPGGVLSLMFYNAHGLLMHNM 160
           +       Q L S    L+PGG+      NA   L H++
Sbjct: 119 METDDMNFQILASAAKALKPGGLFIFTALNALYPLYHSV 157


>UniRef50_B1MM82 Putative uncharacterized protein n=1 Tax=Mycobacterium abscessus
           ATCC 19977 RepID=B1MM82_MYCA9
          Length = 219

 Score = 48.9 bits (115), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 34/105 (32%), Positives = 58/105 (55%), Gaps = 6/105 (5%)

Query: 48  VLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA- 106
           +LDAG G G T++ +A  G+QV+  DLS+  I++AK+AAE   + D +        D+  
Sbjct: 42  ILDAGCGIGSTSLALAGHGYQVVGLDLSSGAIEKAKKAAEPLAL-DVVFDTADLTSDIGY 100

Query: 107 -SHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGG-VLSLMF 149
             H  T +D ++FH +   +      +++L   L+PGG   +L+F
Sbjct: 101 NDHFNTVIDGLVFHCLPAQIRG--DYVRSLARSLKPGGRFFALVF 143


>UniRef50_A0KUS1 Putative uncharacterized protein n=1 Tax=Shewanella sp. ANA-3
           RepID=A0KUS1_SHESA
          Length = 297

 Score = 48.5 bits (114), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 36/130 (27%), Positives = 62/130 (47%), Gaps = 12/130 (9%)

Query: 31  WQDLDRVL-AEMGPQ--KLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAE 87
           W D  +++ +++G    ++ +LD G G GQ      + G        S    D AK+A E
Sbjct: 64  WNDQAKIIESQLGVSMDEIEILDVGCGWGQALSYFKQLGA-------SCYGFDPAKEAVE 116

Query: 88  AKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWS-VLRPGGVLS 146
             G+S  +   HC  + + +      D+++ + VLE +ADP  +L  + S VL+ GG+L 
Sbjct: 117 Y-GISQGLNVKHCGVESMNAFNNKQFDVVMLNNVLEHLADPVKILTEIRSKVLKQGGLLI 175

Query: 147 LMFYNAHGLL 156
           +   N    L
Sbjct: 176 ITVPNDFNTL 185


>UniRef50_A8M0N7 Methyltransferase type 11 n=2 Tax=Micromonosporaceae
           RepID=A8M0N7_SALAI
          Length = 291

 Score = 48.5 bits (114), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 41/138 (29%), Positives = 67/138 (48%), Gaps = 14/138 (10%)

Query: 47  RVLDAGGGEGQTAI---KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQ 103
           RVLD G G G+ AI   ++     +V+  DL+ +M+DRA++ A+  G+   ++F+     
Sbjct: 55  RVLDVGSGTGEPAISAGRLVAPTGRVLGIDLAPEMVDRARRCAD--GLGHPIEFVE---S 109

Query: 104 DVASHLETPV---DLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNM 160
           DV S L+ P    D++     L +  D   VL  L  +L PGGVL+   +       + M
Sbjct: 110 DVES-LDLPADSFDVVFSRWALMFAVDRPRVLTDLRHLLAPGGVLAAAVWGPPE--ANPM 166

Query: 161 VAGNFDYVQAGMPKKKKR 178
            +  F  + A +P    R
Sbjct: 167 TSLAFRTLAADLPPAPDR 184


>UniRef50_Q40JV5 Biotin synthesis protein BioC n=5 Tax=canis group
           RepID=Q40JV5_EHRCH
          Length = 249

 Score = 48.5 bits (114), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 8/119 (6%)

Query: 27  QAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAA 86
           Q ++ ++L   +      K  +LD G G G  +  +    H +I  DLS +M   AK+  
Sbjct: 26  QDVILRELCSTVVLESCDKRNILDVGCGTGNMSKFLNVANHNLIQVDLSREMCVLAKKKN 85

Query: 87  EAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVL 145
            A  V+ +M        DV    E   D+I+   VL+W  D    L  L+ V++  G+L
Sbjct: 86  NALSVNCHM--------DVMPFYENFFDVIIASMVLQWSRDVSISLLELFRVMKSDGIL 136


>UniRef50_Q0RED1 Putative uncharacterized protein n=1 Tax=Frankia alni ACN14a
           RepID=Q0RED1_FRAAA
          Length = 252

 Score = 48.5 bits (114), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 34/110 (30%), Positives = 57/110 (51%), Gaps = 3/110 (2%)

Query: 47  RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA 106
           RVLD   G G  AI  AE G  V   DL+ ++I+R +QAA  +G+S  M+++   A+ + 
Sbjct: 24  RVLDVAAGSGNAAIAAAELGADVTASDLTPKLIERGRQAAADRGIS--MEWLEADAE-LL 80

Query: 107 SHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLL 156
              +   D++L      +  D  +  + L  V RPGG +++  + A G +
Sbjct: 81  PFADEDFDVVLSCIGAMFAPDQAATARELVRVCRPGGTVAMANWTAGGAM 130


>UniRef50_D2L665 Methyltransferase type 11 n=1 Tax=Desulfovibrio sp. FW1012B
           RepID=D2L665_9DELT
          Length = 786

 Score = 48.5 bits (114), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 43/120 (35%), Positives = 60/120 (50%), Gaps = 9/120 (7%)

Query: 37  VLAEMGPQK-LRVLDAGGGEGQTAIKMAER--GHQVILCDLSAQMIDRAKQAAEAKGVSD 93
           V A +G +  L VL AG G GQ A++ A R  G +V+  DLS   +  A++     GV  
Sbjct: 531 VFAPLGARDGLDVLVAGCGTGQHALETARRFRGARVLAVDLSLASLGYARRKTRELGVGG 590

Query: 94  NMQFIHCAAQDVA--SHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYN 151
               I  A  D+   S L    D+I    VL  +ADP +  + L S+LRPGG + L  Y+
Sbjct: 591 ----IEYAQADILGLSDLGRRFDVIESSGVLHHLADPLAGWRVLVSLLRPGGCMRLGLYS 646


>UniRef50_A8M6Z4 Methyltransferase type 11 n=5 Tax=Actinomycetales
           RepID=A8M6Z4_SALAI
          Length = 274

 Score = 48.5 bits (114), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 41/137 (29%), Positives = 70/137 (51%), Gaps = 10/137 (7%)

Query: 47  RVLDAGGGEGQTAIKMAERGH--QVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQD 104
           RVLD G G G+ AI++A   H  +V+   +S + ++RA++ A + G++D + F    A D
Sbjct: 64  RVLDLGCGIGEPAIRLAT-AHTIEVVGISISGRQVERAQERAVSAGLADRLSFELADAMD 122

Query: 105 VASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGN 164
           +  + E   D++     L  + D   VL+ +  VLRPGG +++      G  M    AG 
Sbjct: 123 L-PYPEESFDIVWALESLHHMPDRAHVLRQMTRVLRPGGRVAI------GDFMLLPSAGG 175

Query: 165 FDYVQAGMPKKKKRTLS 181
           ++   A + +  K  LS
Sbjct: 176 YEAGAARVNEASKGVLS 192


>UniRef50_C4RH30 SAM-dependent methyltransferase n=2 Tax=Actinomycetales
           RepID=C4RH30_9ACTO
          Length = 194

 Score = 48.5 bits (114), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 11/96 (11%)

Query: 48  VLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQD--- 104
            LDAG G G  AI +A RG QV   D+SA+ + RA Q A A G S+ +++I   A     
Sbjct: 22  ALDAGCGAGAEAIWLASRGWQVTAVDISAEALARAAQRATASGASERLRWIEADASVWDP 81

Query: 105 ------VASHLETPV--DLILFHAVLEWVADPRSVL 132
                 V +H   P    L  +  V  WVA   ++L
Sbjct: 82  GTRFDLVTTHYAHPAMPQLQFYDRVAGWVASGGTLL 117


>UniRef50_B5K1D7 Methyltransferase, UbiE/COQ5 family n=3 Tax=Rhodobacterales
           RepID=B5K1D7_9RHOB
          Length = 210

 Score = 48.5 bits (114), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 30/99 (30%), Positives = 51/99 (51%), Gaps = 2/99 (2%)

Query: 47  RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA 106
           RVL+ G G G TA+++A    ++   D+S  M + A+  A A G+  N++F    AQD A
Sbjct: 42  RVLEMGCGTGSTALQIAPHVREMTGTDISPVMAEIARTKAAAGGIK-NVEFRVATAQD-A 99

Query: 107 SHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVL 145
           + L    D++L   +   V  P  +   ++++L  GG  
Sbjct: 100 AKLSGTFDVVLGFNLFHLVRAPEDIFDDVYAMLLRGGFF 138


>UniRef50_Q9K8W5 BH2887 protein n=1 Tax=Bacillus halodurans RepID=Q9K8W5_BACHD
          Length = 261

 Score = 48.5 bits (114), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 31/96 (32%), Positives = 47/96 (48%), Gaps = 8/96 (8%)

Query: 48  VLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVAS 107
           VLD G G G    ++ + G +VI  D+S  MI+      +AKG   ++ F    A D++ 
Sbjct: 44  VLDLGCGTGDLTEQIHQLGSRVIGVDVSESMIE------QAKGKFPHLDFQVAEATDLS- 96

Query: 108 HLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGG 143
                 D I  +AVL W+ D    L  ++  L+PGG
Sbjct: 97  -FSEKFDAIFSNAVLHWIKDAEEALTVIYRSLKPGG 131


>UniRef50_B1L4G6 Methyltransferase type 11 n=2 Tax=Archaea RepID=B1L4G6_KORCO
          Length = 262

 Score = 48.5 bits (114), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 41/159 (25%), Positives = 79/159 (49%), Gaps = 25/159 (15%)

Query: 47  RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA 106
           RVLD G G G  +I+   RG++V+  D+S  MI+RA++  +AKG+ +N++F+   A ++ 
Sbjct: 38  RVLDVGCGTGMHSIEFGRRGYEVVGIDVSEDMINRARE--KAKGM-ENVKFLVGDASNM- 93

Query: 107 SHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRP---GGVLSLMFYNAHGLLMHNMVAG 163
             L      I  + V+ +  +  S+++ L +  R    GG+     +N  G++   +   
Sbjct: 94  -ELRGFDVAIAMYGVISYFTEDESLVKFLEAARRSLVDGGLFIFDTWNILGVIEKRV--- 149

Query: 164 NFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQI 202
              Y +  +P+ +K   S           L ++E+ W+I
Sbjct: 150 ---YYEMPIPELRKSGNS-----------LAIKESSWKI 174


>UniRef50_C7QDP7 Methyltransferase type 11 n=3 Tax=Actinomycetales
           RepID=C7QDP7_CATAD
          Length = 258

 Score = 48.1 bits (113), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 34/107 (31%), Positives = 53/107 (49%), Gaps = 3/107 (2%)

Query: 48  VLDAGGGEGQTAIKMAER--GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDV 105
           ++D G G G     +A R    +VI  D S  M+DR + AA ++GV+  ++ +  A  D 
Sbjct: 34  IVDIGAGTGSGTFALARRFEAAEVIAIDQSPTMLDRLQSAAASRGVAGRLRTVQ-ADLDA 92

Query: 106 ASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNA 152
                   DL    + L  VADP  VL  + + L PGG+L ++  +A
Sbjct: 93  GWPAIGTADLAWAASSLHHVADPDRVLADVHAALNPGGLLVVVEMDA 139


>UniRef50_C1PBY7 Methyltransferase type 11 n=1 Tax=Bacillus coagulans 36D1
           RepID=C1PBY7_BACCO
          Length = 237

 Score = 48.1 bits (113), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 34/103 (33%), Positives = 57/103 (55%), Gaps = 5/103 (4%)

Query: 44  QKLRVLDAGGGEGQTAIKMAER-GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAA 102
           +K  VLDAG G GQTA  +A++ G QV   D    M+++A++   + G+   +Q +H   
Sbjct: 38  KKTTVLDAGCGTGQTAAYVAQQYGCQVTGLDHHQLMVEKARKRVRSLGLP--IQIVH-GN 94

Query: 103 QDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVL 145
            +     ++  DL+L  +V+ +   P++V Q    VL+PGG L
Sbjct: 95  TEALPFADSQFDLVLSESVIVFTDMPKTV-QEFQRVLKPGGCL 136


>UniRef50_UPI0001A4295A methyltransferase type 11 n=1 Tax=Pectobacterium carotovorum subsp.
           carotovorum WPP14 RepID=UPI0001A4295A
          Length = 264

 Score = 48.1 bits (113), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 27/104 (25%), Positives = 53/104 (50%), Gaps = 5/104 (4%)

Query: 45  KLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQD 104
           K +++D GG  G  + ++A+ GH+V L D++   I++AK+ +   GV  ++   H     
Sbjct: 42  KQKIIDIGGATGIYSFELAKLGHEVDLFDIAPIHIEKAKKISAETGV--DLHGFHIGDAQ 99

Query: 105 VASHLETPVDLILFHAVLEWVADPR---SVLQTLWSVLRPGGVL 145
             +  +   D ++ H  L  + D      VL+  + V++P G+L
Sbjct: 100 NLAFSDNSFDTVILHGPLYHITDESLRLRVLKEAYRVMKPEGIL 143


>UniRef50_C5BMU9 SAM-dependent methyltransferase n=1 Tax=Teredinibacter turnerae
           T7901 RepID=C5BMU9_TERTT
          Length = 206

 Score = 48.1 bits (113), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 31/100 (31%), Positives = 55/100 (55%), Gaps = 2/100 (2%)

Query: 46  LRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDV 105
           +RVL+ G G G  A++ A      +  D+S +M++ A++   A G++ N+QF+  A +  
Sbjct: 41  MRVLEFGCGTGSMAVRHAPLVADYVAIDVSFKMLEIAEKKRSAAGLA-NLQFMRDAIES- 98

Query: 106 ASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVL 145
            S      DL++  ++L  V D  +VL  L + L+PGG+ 
Sbjct: 99  RSLGRAHFDLVMGFSILHLVRDLDAVLHKLHTALKPGGLF 138


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_P36566 Protein smtA n=113 Tax=Gammaproteobacteria RepID...   403   e-111
UniRef50_C4X686 S-adenosylmethionine-dependent methyltransferase...   356   3e-97
UniRef50_B0TUI9 Methyltransferase type 12 n=65 Tax=Gammaproteoba...   280   3e-74
UniRef50_Q5QZ69 SAM-dependent methyltransferase n=3 Tax=Alteromo...   280   3e-74
UniRef50_A3QA14 Methyltransferase type 12 n=16 Tax=Gammaproteoba...   274   2e-72
UniRef50_Q1ZIA5 SmtA protein n=2 Tax=Gammaproteobacteria RepID=Q...   269   6e-71
UniRef50_B3PES7 SmtA protein n=1 Tax=Cellvibrio japonicus Ueda10...   267   3e-70
UniRef50_Q2SJW8 SAM-dependent methyltransferase n=1 Tax=Hahella ...   259   6e-68
UniRef50_Q1YTE5 Possible methyltransferase n=1 Tax=gamma proteob...   255   9e-67
UniRef50_Q15TU3 Methyltransferase type 11 n=1 Tax=Pseudoalteromo...   244   2e-63
UniRef50_A4XQ92 Methyltransferase type 11 n=17 Tax=Pseudomonas R...   244   3e-63
UniRef50_Q31JJ3 SAM-dependent methyltransferase n=3 Tax=Pisciric...   244   3e-63
UniRef50_A4VI82 Methyltransferase, putative n=5 Tax=Pseudomonada...   241   1e-62
UniRef50_C5BHU7 SAM-dependent methyltransferase n=1 Tax=Teredini...   241   2e-62
UniRef50_UPI0000E11711 methyltransferase type 11 n=1 Tax=Glaciec...   240   3e-62
UniRef50_B4RYI5 SAM-dependent methyltransferase n=2 Tax=Alteromo...   238   2e-61
UniRef50_Q21JL0 Methyltransferase type 12 n=1 Tax=Saccharophagus...   237   3e-61
UniRef50_Q1QA01 Methyltransferase type 11 n=4 Tax=Moraxellaceae ...   234   3e-60
UniRef50_Q2NUA0 Putative S-adenosylmethionine-dependent methyltr...   228   1e-58
UniRef50_Q1QUF1 SmtA protein n=1 Tax=Chromohalobacter salexigens...   225   1e-57
UniRef50_A5EV89 S-adenosylmethionine-dependent methyltransferase...   224   2e-57
UniRef50_Q1N5H2 SAM-dependent methyltransferase n=1 Tax=Bermanel...   222   8e-57
UniRef50_B5L6J9 Methyltransferase n=1 Tax=Micromonospora chalcea...   184   3e-45
UniRef50_B3TMR6 SAM-dependent methyltransferase n=1 Tax=Actinoma...   178   1e-43
UniRef50_D1V817 Methyltransferase type 12 n=2 Tax=Frankia RepID=...   178   2e-43
UniRef50_A4BJS3 Putative SmtA protein n=1 Tax=Reinekea blandensi...   177   3e-43
UniRef50_A3TKD6 Putative methyltransferase n=1 Tax=Janibacter sp...   172   1e-41
UniRef50_A3TLQ5 S-adenosylmethionine-dependent methyltransferase...   172   1e-41
UniRef50_B9K8U5 Ubiquinone/menaquinone biosynthesis methyltransf...   170   5e-41
UniRef50_D2SA73 Methyltransferase type 11 n=1 Tax=Geodermatophil...   168   2e-40
UniRef50_A4FIW0 Methyltransferase n=3 Tax=Actinomycetales RepID=...   168   2e-40
UniRef50_B4V3L4 Methyltransferase n=17 Tax=Streptomyces RepID=B4...   167   4e-40
UniRef50_C7QBJ1 Methyltransferase type 12 n=15 Tax=Actinomycetal...   166   9e-40
UniRef50_C0ZNJ7 Putative methyltransferase n=1 Tax=Rhodococcus e...   165   9e-40
UniRef50_A8M0L9 Methyltransferase type 12 n=1 Tax=Salinispora ar...   164   3e-39
UniRef50_C5CH90 Methyltransferase type 11 n=1 Tax=Kosmotoga olea...   163   7e-39
UniRef50_Q46F96 Ubiquinone/menaquinone biosynthesis methyltransf...   161   2e-38
UniRef50_D1VJQ5 Methyltransferase type 12 n=1 Tax=Frankia sp. Eu...   160   6e-38
UniRef50_UPI0001B4EB31 methyltransferase n=1 Tax=Streptomyces sp...   156   5e-37
UniRef50_C9NJ50 Methyltransferase type 12 n=8 Tax=Streptomyces R...   156   9e-37
UniRef50_Q2JD64 Methyltransferase type 11 n=2 Tax=Frankia RepID=...   155   1e-36
UniRef50_C9R8S5 Methyltransferase type 11 n=1 Tax=Ammonifex dege...   154   2e-36
UniRef50_A8MFN6 Methyltransferase type 11 n=1 Tax=Alkaliphilus o...   153   8e-36
UniRef50_B1BEI5 Probable S-adenosylmethionine-dependent methltra...   152   9e-36
UniRef50_A6WCY9 Methyltransferase type 12 n=2 Tax=Actinomycetale...   151   3e-35
UniRef50_D0RTX5 S-adenosylmethionine-dependent methyltransferase...   150   3e-35
UniRef50_A8MFN7 Methyltransferase type 11 n=1 Tax=Alkaliphilus o...   150   7e-35
UniRef50_B0U3W1 3-demethylubiquinone-9 3-methyltransferase n=7 T...   149   1e-34
UniRef50_C8SD34 Methyltransferase type 11 n=1 Tax=Ferroglobus pl...   147   4e-34
UniRef50_A6WDP8 Methyltransferase type 12 n=1 Tax=Kineococcus ra...   146   4e-34
UniRef50_A4FLY1 Methyltransferase n=1 Tax=Saccharopolyspora eryt...   146   7e-34
UniRef50_Q6MHC4 3-demethylubiquinone-9 3-methyltransferase n=1 T...   144   3e-33
UniRef50_D1JEE5 Putative uncharacterized protein n=1 Tax=uncultu...   143   5e-33
UniRef50_Q2FMN6 UbiE/COQ5 methyltransferase n=1 Tax=Methanospiri...   142   1e-32
UniRef50_Q0F561 3-demethylubiquinone-9 3-methyltransferase n=2 T...   140   6e-32
UniRef50_D1JD52 Putative uncharacterized protein n=1 Tax=uncultu...   139   7e-32
UniRef50_Q482G8 3-demethylubiquinone-9 3-methyltransferase n=27 ...   139   7e-32
UniRef50_Q2FPU4 UbiE/COQ5 methyltransferase n=1 Tax=Methanospiri...   139   7e-32
UniRef50_C8XH01 Methyltransferase type 11 n=1 Tax=Nakamurella mu...   138   1e-31
UniRef50_A7MPA9 3-demethylubiquinone-9 3-methyltransferase n=6 T...   138   2e-31
UniRef50_D1JD78 Putative uncharacterized protein n=1 Tax=uncultu...   138   2e-31
UniRef50_Q8TJ84 UbiE/COQ5 methyltransferase n=1 Tax=Methanosarci...   138   2e-31
UniRef50_D1JD67 Putative uncharacterized protein n=1 Tax=uncultu...   138   2e-31
UniRef50_Q1QEI9 3-demethylubiquinone-9 3-methyltransferase n=59 ...   136   5e-31
UniRef50_Q3MEY9 Cyclopropane-fatty-acyl-phospholipid synthase n=...   136   9e-31
UniRef50_C6PRH7 Methyltransferase type 11 n=1 Tax=Clostridium ca...   135   1e-30
UniRef50_B1KQ47 Ubiquinone biosynthesis O-methyltransferase n=3 ...   135   1e-30
UniRef50_C0Q9K2 UbiG n=1 Tax=Desulfobacterium autotrophicum HRM2...   135   1e-30
UniRef50_Q8TJW5 Putative uncharacterized protein n=1 Tax=Methano...   135   2e-30
UniRef50_Q8TIA7 Phosphatidylethanolamine N-methyltransferase n=3...   134   3e-30
UniRef50_A6UUC3 Methyltransferase type 11 n=1 Tax=Methanococcus ...   134   3e-30
UniRef50_D2RYJ5 Methyltransferase type 11 n=3 Tax=Haloterrigena ...   134   3e-30
UniRef50_UPI0001AF209D methyltransferase type 11 n=1 Tax=Strepto...   133   4e-30
UniRef50_Q46ER7 UbiE/COQ5 methyltransferase n=4 Tax=Methanosarci...   133   6e-30
UniRef50_B1I4Q7 Methyltransferase type 11 n=1 Tax=Candidatus Des...   133   6e-30
UniRef50_Q21UL3 3-demethylubiquinone-9 3-methyltransferase n=5 T...   133   7e-30
UniRef50_Q65VD6 SmtA protein n=2 Tax=Gammaproteobacteria RepID=Q...   133   7e-30
UniRef50_Q47QY4 Putative methyltransferase n=1 Tax=Thermobifida ...   132   1e-29
UniRef50_Q5WCE8 S-adenosylmethionine (SAM)-dependent methyltrans...   132   1e-29
UniRef50_C9L9K2 SmtA protein n=6 Tax=Bacteria RepID=C9L9K2_RUMHA      132   1e-29
UniRef50_C5A2C6 SAM-dependent methyltransferase, ubiE/COQ5 famil...   131   2e-29
UniRef50_A0Y980 3-demethylubiquinone-9 3-methyltransferase n=1 T...   131   2e-29
UniRef50_B8H209 3-demethylubiquinone-9 3-methyltransferase n=13 ...   131   3e-29
UniRef50_B5JEA6 Methyltransferase domain family n=1 Tax=Verrucom...   129   8e-29
UniRef50_Q465A0 Putative uncharacterized protein n=2 Tax=Methano...   129   8e-29
UniRef50_Q2FPT3 UbiE/COQ5 methyltransferase n=1 Tax=Methanospiri...   129   8e-29
UniRef50_A4FIY5 Ubiquinone/menaquinone biosynthesis methyltransf...   129   1e-28
UniRef50_A8J700 C5-O-methyltransferase n=4 Tax=Streptomyces RepI...   128   2e-28
UniRef50_A4Z3A6 Putative uncharacterized protein n=1 Tax=Bradyrh...   128   2e-28
UniRef50_UPI000186D07C hexaprenyldihydroxybenzoate methyltransfe...   128   2e-28
UniRef50_Q467Y8 Methyltransferase n=2 Tax=Methanosarcina RepID=Q...   128   2e-28
UniRef50_A5EVK0 Ubiquinone biosynthesis O-methyltransferase n=2 ...   127   3e-28
UniRef50_O74421 Hexaprenyldihydroxybenzoate methyltransferase, m...   127   3e-28
UniRef50_B0A8V1 Putative uncharacterized protein n=1 Tax=Clostri...   127   3e-28
UniRef50_Q48938 Orf3 protein n=3 Tax=Methanosarcina RepID=Q48938...   127   4e-28
UniRef50_Q012C7 Dihydroxypolyprenylbenzoate methyltransferase (I...   126   5e-28
UniRef50_D1BDI2 Methylase involved in ubiquinone/menaquinone bio...   126   6e-28
UniRef50_Q033A8 SAM-dependent methyltransferase n=6 Tax=Firmicut...   126   6e-28
UniRef50_A5ZYR5 Putative uncharacterized protein (Fragment) n=1 ...   126   8e-28
UniRef50_Q89BX8 Bll8020 protein n=1 Tax=Bradyrhizobium japonicum...   126   1e-27
UniRef50_Q8TPQ8 UbiE/COQ5 methyltransferase n=1 Tax=Methanosarci...   126   1e-27
UniRef50_B7FTF3 Predicted protein (Fragment) n=1 Tax=Phaeodactyl...   126   1e-27
UniRef50_D2LFP9 Ubiquinone biosynthesis O-methyltransferase n=1 ...   125   1e-27
UniRef50_Q46F92 Putative uncharacterized protein n=2 Tax=Methano...   125   1e-27
UniRef50_B0XJ66 3-demethylubiquinone-9 3-methyltransferase n=2 T...   125   2e-27
UniRef50_Q73R34 Methlytransferase, UbiE/COQ5 family n=1 Tax=Trep...   125   2e-27
UniRef50_Q2RJ99 UbiE/COQ5 methyltransferase n=1 Tax=Moorella the...   125   2e-27
UniRef50_C5RP33 Methyltransferase type 11 n=1 Tax=Clostridium ce...   124   3e-27
UniRef50_B8FRY0 Methyltransferase type 12 n=2 Tax=Desulfitobacte...   124   3e-27
UniRef50_C6C7H1 Methyltransferase type 11 n=3 Tax=Enterobacteria...   124   4e-27
UniRef50_D1CAG8 Methyltransferase type 11 n=1 Tax=Sphaerobacter ...   124   4e-27
UniRef50_Q21DX2 Methyltransferase type 11 n=2 Tax=Gammaproteobac...   123   5e-27
UniRef50_A7I8W9 Methyltransferase type 11 n=3 Tax=Methanomicrobi...   123   6e-27
UniRef50_C6D045 Methyltransferase type 11 n=24 Tax=Bacillales Re...   123   6e-27
UniRef50_C4G5R9 Putative uncharacterized protein n=1 Tax=Abiotro...   122   1e-26
UniRef50_Q02BK2 Methyltransferase type 12 n=1 Tax=Candidatus Sol...   122   1e-26
UniRef50_C8VZ57 Methyltransferase type 11 n=1 Tax=Desulfotomacul...   122   1e-26
UniRef50_B8HW44 Methyltransferase type 11 n=2 Tax=Bacteria RepID...   122   1e-26
UniRef50_Q7VRW8 3-demethylubiquinone-9 3-methyltransferase n=2 T...   121   2e-26
UniRef50_D1JD56 Putative uncharacterized protein n=1 Tax=uncultu...   121   2e-26
UniRef50_Q9K8W5 BH2887 protein n=1 Tax=Bacillus halodurans RepID...   121   2e-26
UniRef50_Q7Q8W1 AGAP010535-PA n=1 Tax=Anopheles gambiae RepID=Q7...   121   2e-26
UniRef50_C6PBK3 Methyltransferase type 11 n=1 Tax=Thermoanaeroba...   121   3e-26
UniRef50_A9G9E0 Putative uncharacterized protein n=1 Tax=Sorangi...   121   3e-26
UniRef50_A6C296 UbiE/COQ5 methyltransferase n=2 Tax=Planctomycet...   121   3e-26
UniRef50_D1VDC2 Methyltransferase type 11 n=1 Tax=Frankia sp. Eu...   121   3e-26
UniRef50_C7MH99 Methylase involved in ubiquinone/menaquinone bio...   121   3e-26
UniRef50_C9L9K1 SmtA protein n=1 Tax=Blautia hansenii DSM 20583 ...   121   3e-26
UniRef50_C2HDY5 S-adenosylmethionine-dependent methyltransferase...   120   4e-26
UniRef50_B9JTF4 Ubiquinone biosynthesis O-methyltransferase n=1 ...   120   4e-26
UniRef50_B2J5L2 Methyltransferase type 11 n=1 Tax=Nostoc punctif...   120   5e-26
UniRef50_B5JNH0 Methyltransferase domain family n=1 Tax=Verrucom...   120   5e-26
UniRef50_D1A8N4 Methyltransferase type 11 n=2 Tax=Streptosporang...   120   6e-26
UniRef50_B8EI29 3-demethylubiquinone-9 3-methyltransferase n=1 T...   120   6e-26
UniRef50_Q97TL7 SAM-dependent methyltransferase n=2 Tax=Clostrid...   120   6e-26
UniRef50_A8PNX2 3-demethylubiquinone-9 3-O-methyltransferase n=1...   120   7e-26
UniRef50_C9LTF9 SmtA protein n=2 Tax=Veillonellaceae RepID=C9LTF...   120   7e-26
UniRef50_UPI0001B57FBF MCP methyltransferase, CheR-type n=1 Tax=...   119   8e-26
UniRef50_A1R990 Menaquinone biosynthesis methyltransferase ubiE ...   119   1e-25
UniRef50_B2WBS7 Methyltransferase UbiE n=2 Tax=Pleosporineae Rep...   119   1e-25
UniRef50_B4V763 Putative uncharacterized protein n=4 Tax=Strepto...   119   1e-25
UniRef50_Q9EYI2 SnogM n=1 Tax=Streptomyces nogalater RepID=Q9EYI...   119   1e-25
UniRef50_Q47PB3 S-adenosylmethionine (SAM)-dependent methyltrans...   118   2e-25
UniRef50_B6Q7B1 UbiE/COQ5 methyltransferase, putative n=1 Tax=Pe...   118   2e-25
UniRef50_C6A0V9 Cyclopropane-fatty-acyl-phospholipid synthase su...   118   3e-25
UniRef50_D2QHG7 Methyltransferase type 11 n=1 Tax=Spirosoma ling...   117   3e-25
UniRef50_B9XT55 Methyltransferase type 11 n=1 Tax=bacterium Elli...   117   3e-25
UniRef50_D1Z1A4 Putative uncharacterized protein n=1 Tax=Methano...   116   5e-25
UniRef50_A4X9U1 Methyltransferase type 11 n=5 Tax=Actinomycetale...   116   5e-25
UniRef50_Q01S22 Methyltransferase type 11 n=1 Tax=Candidatus Sol...   116   6e-25
UniRef50_Q8R7K7 SAM-dependent methyltransferases n=7 Tax=Thermoa...   116   7e-25
UniRef50_B4WI79 Methyltransferase domain family n=1 Tax=Synechoc...   116   8e-25
UniRef50_Q9RYC4 Methyltransferase, putative n=2 Tax=Deinococcus ...   116   8e-25
UniRef50_A3XJF1 Putative uncharacterized protein n=1 Tax=Leeuwen...   116   1e-24
UniRef50_A4EUG7 Methyltransferase, UbiE/COQ5 family protein n=5 ...   116   1e-24
UniRef50_C5FG45 Crg1p n=1 Tax=Microsporum canis CBS 113480 RepID...   115   1e-24
UniRef50_P08442 Uncharacterized protein syc1184_c n=29 Tax=Cyano...   115   1e-24
UniRef50_B0SGJ1 Methylase/methyltransferase n=2 Tax=Leptospira b...   115   1e-24
UniRef50_A8M6Z4 Methyltransferase type 11 n=5 Tax=Actinomycetale...   115   1e-24
UniRef50_A8FSR8 Methylase involved in ubiquinone/menaquinone bio...   115   1e-24
UniRef50_D2B333 Methyltransferase type 11 n=4 Tax=Actinomycetale...   115   1e-24
UniRef50_Q8U2V0 Putative uncharacterized protein n=1 Tax=Pyrococ...   115   1e-24
UniRef50_D0MGM2 Methyltransferase type 11 n=3 Tax=root RepID=D0M...   115   2e-24
UniRef50_B7KGA5 Methyltransferase type 11 n=2 Tax=Cyanothece Rep...   115   2e-24

Sequences not found previously or not previously below threshold:

UniRef50_D1JD55 Putative uncharacterized protein n=1 Tax=uncultu...   139   8e-32
UniRef50_B6BTP2 3-demethylubiquinone-9 3-O-methyltransferase n=1...   133   6e-30
UniRef50_B8GRY2 Ubiquinone biosynthesis O-methyltransferase n=1 ...   132   1e-29
UniRef50_B3S9Y1 Putative uncharacterized protein n=1 Tax=Trichop...   132   1e-29
UniRef50_B6YVU2 UbiE/COQ5 methyltransferase n=4 Tax=Thermococcus...   132   1e-29
UniRef50_B7MFZ8 3-demethylubiquinone-9 3-methyltransferase n=131...   131   3e-29
UniRef50_B8HNX7 Ubiquinone biosynthesis O-methyltransferase n=1 ...   130   3e-29
UniRef50_C8WEG5 Ubiquinone biosynthesis O-methyltransferase n=3 ...   130   6e-29
UniRef50_Q28VP7 3-demethylubiquinone-9 3-methyltransferase n=37 ...   130   6e-29
UniRef50_Q9NZJ6 Hexaprenyldihydroxybenzoate methyltransferase, m...   129   9e-29
UniRef50_A0L9I8 3-demethylubiquinone-9 3-methyltransferase n=2 T...   129   1e-28
UniRef50_C4XNC1 Putative 3-demethylubiquinone-9 3-methyltransfer...   128   2e-28
UniRef50_Q2NSL7 3-demethylubiquinone-9 3-methyltransferase n=305...   128   2e-28
UniRef50_Q3SVP3 3-demethylubiquinone-9 3-methyltransferase n=45 ...   127   3e-28
UniRef50_D1YW16 ABC transporter ATP binding protein n=3 Tax=Meth...   126   9e-28
UniRef50_Q8TNX2 Putative uncharacterized protein n=1 Tax=Methano...   125   2e-27
UniRef50_C6CNR0 Methyltransferase type 11 n=2 Tax=Dickeya RepID=...   124   3e-27
UniRef50_B9M2E9 Ubiquinone biosynthesis O-methyltransferase n=1 ...   124   3e-27
UniRef50_A2SPT6 Methyltransferase type 11 n=2 Tax=Methanomicrobi...   124   3e-27
UniRef50_C1MP91 Predicted protein n=1 Tax=Micromonas pusilla CCM...   124   3e-27
UniRef50_Q465A3 UbiE/COQ5 methyltransferase n=3 Tax=Methanomicro...   124   4e-27
UniRef50_Q5WW02 3-demethylubiquinone-9 3-methyltransferase n=4 T...   123   5e-27
UniRef50_B4RRL2 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-ben...   123   5e-27
UniRef50_C8W4V3 Methyltransferase type 11 n=1 Tax=Desulfotomacul...   123   6e-27
UniRef50_Q46D00 UbiE/COQ5 methyltransferase n=2 Tax=Methanosarci...   123   6e-27
UniRef50_C7MMN1 Methylase involved in ubiquinone/menaquinone bio...   123   7e-27
UniRef50_D0NUY8 3-demethylubiquinone-9 3-methyltransferase, puta...   122   1e-26
UniRef50_A9KR97 Methyltransferase type 11 n=1 Tax=Clostridium ph...   122   1e-26
UniRef50_UPI000051ABE2 PREDICTED: similar to coenzyme Q3 homolog...   121   2e-26
UniRef50_B0C971 Methyltransferase, putative n=1 Tax=Acaryochlori...   121   2e-26
UniRef50_UPI0000E495F1 PREDICTED: hypothetical protein n=2 Tax=S...   121   2e-26
UniRef50_Q8NMH1 SAM-dependent methyltransferases n=2 Tax=Coryneb...   121   2e-26
UniRef50_Q67LB5 Conserved domain protein n=1 Tax=Symbiobacterium...   121   3e-26
UniRef50_Q5PAV2 3-demethylubiquinone-9 3-methyltransferase n=1 T...   121   3e-26
UniRef50_A1HPJ4 Methyltransferase type 11 n=1 Tax=Thermosinus ca...   121   3e-26
UniRef50_C5KJI6 3-demethylubiquinone-9 3-methyltransferase, puta...   121   3e-26
UniRef50_B3E0R3 Methylase involved in ubiquinone/menaquinone bio...   121   3e-26
UniRef50_B8GH63 Methyltransferase type 11 n=1 Tax=Methanosphaeru...   120   3e-26
UniRef50_B9XIN5 Ubiquinone/menaquinone biosynthesis methyltransf...   120   6e-26
UniRef50_D1BE92 Methylase involved in ubiquinone/menaquinone bio...   120   6e-26
UniRef50_B0MSN4 Putative uncharacterized protein n=1 Tax=Alistip...   120   7e-26
UniRef50_A4B9Z3 3-demethylubiquinone-9 3-methyltransferase n=2 T...   120   7e-26
UniRef50_A8TN90 Ubiquinone biosynthesis O-methyltransferase n=1 ...   120   7e-26
UniRef50_B0A8V0 Putative uncharacterized protein n=1 Tax=Clostri...   119   8e-26
UniRef50_C3YXC3 Putative uncharacterized protein n=1 Tax=Branchi...   119   8e-26
UniRef50_C6P0T7 Methyltransferase type 11 n=1 Tax=Sideroxydans l...   119   8e-26
UniRef50_B0C3T5 Methyltransferase n=8 Tax=Bacteria RepID=B0C3T5_...   119   9e-26
UniRef50_B1I444 Methyltransferase type 11 n=1 Tax=Candidatus Des...   119   1e-25
UniRef50_Q1GR70 3-demethylubiquinone-9 3-methyltransferase n=1 T...   119   1e-25
UniRef50_A6TPQ5 Methyltransferase type 11 n=1 Tax=Alkaliphilus m...   119   1e-25
UniRef50_D1RIV9 3-demethylubiquinone-9 3-O-methyltransferase n=1...   119   1e-25
UniRef50_B8G1N6 Methyltransferase type 11 n=1 Tax=Desulfitobacte...   118   1e-25
UniRef50_Q1JXN0 Methyltransferase type 11 n=1 Tax=Desulfuromonas...   118   1e-25
UniRef50_A2R2U4 Contig An14c0090, complete genome n=32 Tax=cellu...   118   1e-25
UniRef50_D0BKF2 SmtA protein n=1 Tax=Granulicatella elegans ATCC...   118   1e-25
UniRef50_Q235E0 Ubiquinone biosynthesis O-methyltransferase fami...   118   2e-25
UniRef50_Q9ALM7 Methyltransferase-like protein n=2 Tax=Saccharop...   118   2e-25
UniRef50_Q2GKA5 3-demethylubiquinone-9 3-methyltransferase n=7 T...   118   2e-25
UniRef50_Q5GT88 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-be...   118   2e-25
UniRef50_A7AUT3 Ubiquinone biosynthesis O-methyltransferase fami...   118   3e-25
UniRef50_Q8RJX7 Methyl transferase n=1 Tax=Stigmatella aurantiac...   117   3e-25
UniRef50_B4U0G0 S-adenosylmethionine-dependent methyltransferase...   117   3e-25
UniRef50_A0LNU5 3-demethylubiquinone-9 3-methyltransferase n=1 T...   117   3e-25
UniRef50_A6F2N0 SAM-dependent methyltransferase n=1 Tax=Marinoba...   117   3e-25
UniRef50_Q88SI6 Menaquinone biosynthesis methyltransferase ubiE ...   117   4e-25
UniRef50_Q5VMJ1 Putative dihydroxypolyprenylbenzoate methyltrans...   117   4e-25
UniRef50_Q21PF3 Methyltransferase type 11 n=1 Tax=Saccharophagus...   117   4e-25
UniRef50_Q2CBK3 Methyltransferase, UbiE/COQ5 family protein n=1 ...   116   5e-25
UniRef50_A4S2A7 Predicted protein n=1 Tax=Ostreococcus lucimarin...   116   5e-25
UniRef50_A4X7A0 Methyltransferase type 11 n=9 Tax=Bacteria RepID...   116   5e-25
UniRef50_A0ZM88 3-demethylubiquinone-9 3-methyltransferase n=1 T...   116   5e-25
UniRef50_C7PC96 Methyltransferase type 11 n=1 Tax=Chitinophaga p...   116   5e-25
UniRef50_D1Z1F5 Putative uncharacterized protein n=1 Tax=Methano...   116   6e-25
UniRef50_C8Q6G5 Methyltransferase type 11 n=1 Tax=Pantoea sp. At...   116   7e-25
UniRef50_D0LMD2 Methyltransferase type 11 n=1 Tax=Haliangium och...   116   7e-25
UniRef50_B8FPB3 Methyltransferase type 11 n=4 Tax=Clostridiales ...   116   8e-25
UniRef50_Q67LE6 Menaquinone biosynthesis methyltransferase ubiE ...   116   8e-25
UniRef50_A1TE65 Methyltransferase type 11 n=1 Tax=Mycobacterium ...   116   9e-25
UniRef50_A8ICE1 Hexaprenyldihydroxybenzoate methyltransferase (F...   116   9e-25
UniRef50_Q65P11 Putative uncharacterized protein n=4 Tax=Bacilli...   116   9e-25
UniRef50_B8G0Y2 Methyltransferase type 11 n=1 Tax=Desulfitobacte...   116   1e-24
UniRef50_Q0S6F7 3-demethylubiquinone-9 3-O-methyltransferase n=3...   116   1e-24
UniRef50_D2UX54 Predicted protein (Fragment) n=1 Tax=Naegleria g...   115   1e-24
UniRef50_Q0W5X8 Ubiquinone/menaquinone biosynthesis methyltransf...   115   1e-24
UniRef50_A7S2R8 Predicted protein n=1 Tax=Nematostella vectensis...   115   1e-24
UniRef50_B2JBN9 Methyltransferase type 11 n=2 Tax=Cyanobacteria ...   115   2e-24

>UniRef50_P36566 Protein smtA n=113 Tax=Gammaproteobacteria RepID=SMTA_ECOLI
          Length = 261

 Score =  403 bits (1036), Expect = e-111,   Method: Composition-based stats.
 Identities = 261/261 (100%), Positives = 261/261 (100%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI
Sbjct: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
           KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA
Sbjct: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
           VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL
Sbjct: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180

Query: 181 SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP 240
           SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP
Sbjct: 181 SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP 240

Query: 241 YITLGRYIHVTARKPQSKDKV 261
           YITLGRYIHVTARKPQSKDKV
Sbjct: 241 YITLGRYIHVTARKPQSKDKV 261


>UniRef50_C4X686 S-adenosylmethionine-dependent methyltransferase n=56
           Tax=Enterobacteriaceae RepID=C4X686_KLEPN
          Length = 270

 Score =  356 bits (915), Expect = 3e-97,   Method: Composition-based stats.
 Identities = 208/266 (78%), Positives = 230/266 (86%), Gaps = 5/266 (1%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           +QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDL+ +LA++GP  LRVLDAGGGEGQTAI
Sbjct: 5   VQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLEPLLAQLGPGPLRVLDAGGGEGQTAI 64

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
           K+A+ GH V LCDLSA+M+ RA+QAA  KGV DNM F+ CAAQD+A HLE+PVDL+LFHA
Sbjct: 65  KVAQLGHHVTLCDLSAEMVARARQAAADKGVIDNMHFVQCAAQDIAQHLESPVDLVLFHA 124

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
           VLEWVA+P+ +L TLWS LR GG LSLMFYNA+GLLMHNMVAGNFDYVQ GMPKKKKRTL
Sbjct: 125 VLEWVAEPQEILHTLWSTLRAGGGLSLMFYNANGLLMHNMVAGNFDYVQLGMPKKKKRTL 184

Query: 181 SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP 240
           SPDYPR+P QVY WLEE GWQI+ KTGVRVFHDYLREK QQ D Y ALL LETRYCRQEP
Sbjct: 185 SPDYPREPQQVYHWLEEIGWQIVSKTGVRVFHDYLREKRQQHDSYAALLALETRYCRQEP 244

Query: 241 YITLGRYIHVTARKPQ-----SKDKV 261
           Y++LGRYIHVTA K Q      KDKV
Sbjct: 245 YLSLGRYIHVTALKSQAHSRRCKDKV 270


>UniRef50_B0TUI9 Methyltransferase type 12 n=65 Tax=Gammaproteobacteria
           RepID=B0TUI9_SHEHH
          Length = 287

 Score =  280 bits (717), Expect = 3e-74,   Method: Composition-based stats.
 Identities = 124/261 (47%), Positives = 176/261 (67%), Gaps = 6/261 (2%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQK------LRVLDAGGGE 55
           QDRNFD +A KF+ +IYGT KG++RQ ++WQD++++L  +  Q       L VLDAGGG 
Sbjct: 27  QDRNFDGLAHKFAASIYGTAKGEIRQTVVWQDIEQILLALSKQPSNAAAELSVLDAGGGL 86

Query: 56  GQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDL 115
            Q + K+A  GH V LCDLS++M+  AKQ      +    QFIH   Q++A HL+ PVDL
Sbjct: 87  AQLSQKIAALGHNVSLCDLSSEMLSLAKQDISDNQLLKKYQFIHSPVQNIAEHLQVPVDL 146

Query: 116 ILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKK 175
           ILFHAV+EW+A+P   L TL   ++PGG++S+MFYN +GLL  N++ GN ++++ GMP +
Sbjct: 147 ILFHAVMEWLAEPIQALSTLCEQVKPGGIISVMFYNYNGLLFKNLICGNLNHIEKGMPHR 206

Query: 176 KKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRY 235
           K+  L P     P  VY  LE+AG+ I+GKTGVR FHDY++        +E ++ +E + 
Sbjct: 207 KRFKLQPQQGIKPELVYSCLEQAGFNILGKTGVRTFHDYMQNHDMGDFSFEQIVAMEQKL 266

Query: 236 CRQEPYITLGRYIHVTARKPQ 256
           CRQEP+++LGRYIHV A+K  
Sbjct: 267 CRQEPFLSLGRYIHVYAQKSA 287


>UniRef50_Q5QZ69 SAM-dependent methyltransferase n=3 Tax=Alteromonadales
           RepID=Q5QZ69_IDILO
          Length = 262

 Score =  280 bits (716), Expect = 3e-74,   Method: Composition-based stats.
 Identities = 110/261 (42%), Positives = 157/261 (60%), Gaps = 6/261 (2%)

Query: 2   QDR-NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           Q+R +F  I++KFS++IY TTKGQLR  +L +DL  +LA    +   VLD G G GQ   
Sbjct: 6   QERGDFSGISQKFSKSIYDTTKGQLRVEVLKRDLAPLLAT---EPCLVLDVGAGLGQVNQ 62

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLE-TPVDLILFH 119
              E+G  V+  DLS +MI+ A++  +A G+    +++  +  ++ +    +  D+IL H
Sbjct: 63  WFQEKGFTVVHSDLSTEMIEEAERRHKAAGLGHKCKYVAASLTELVNQQPLSQYDIILCH 122

Query: 120 AVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRT 179
           AVLEW+ D    +  L S+L+PGG LSLMFYN H  L  N + GNFDY++ G+  KK   
Sbjct: 123 AVLEWLPDTELAIHQLASLLKPGGKLSLMFYNYHAKLFANAIYGNFDYIERGLKVKKTVR 182

Query: 180 LSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQE 239
           LSP+ P  P QV  WLE+ G  +  KTGVR FHDYLR+   Q+  ++ LL LE +Y +  
Sbjct: 183 LSPENPAVPEQVGCWLEQEGLNVQQKTGVRCFHDYLRDLTHQQR-FDELLALEMKYNQMS 241

Query: 240 PYITLGRYIHVTARKPQSKDK 260
           PY  LGRY H    KP  +++
Sbjct: 242 PYRELGRYQHWLIEKPNCQEE 262


>UniRef50_A3QA14 Methyltransferase type 12 n=16 Tax=Gammaproteobacteria
           RepID=A3QA14_SHELP
          Length = 284

 Score =  274 bits (701), Expect = 2e-72,   Method: Composition-based stats.
 Identities = 101/257 (39%), Positives = 151/257 (58%), Gaps = 4/257 (1%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           +QD+NFD +A KF++NIYGT KG++R A+LW+D+ + + ++    LR+LDAGGG G  + 
Sbjct: 25  VQDKNFDALAGKFAKNIYGTPKGEVRAAVLWRDISQAMTQLPEGPLRILDAGGGFGFFSQ 84

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEA----KGVSDNMQFIHCAAQDVASHLETPVDLI 116
           K+A+ GH V LCD+S++M+   +          G   ++  +H   Q +        DLI
Sbjct: 85  KLAKLGHSVTLCDISSEMLALGQAQITEYENNSGEKLDITLLHAPIQSLTREELGQFDLI 144

Query: 117 LFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKK 176
           L HAV EW++D +  L  L  +L+P G+ SLMFYN   +  H++++GNFDYV A    KK
Sbjct: 145 LCHAVAEWLSDAKQTLAGLTQLLKPQGLFSLMFYNKEAMRFHSLISGNFDYVAADFKVKK 204

Query: 177 KRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYC 236
           K  L+P YP     V  W+ +   +++  +GVRV HDYL+        +  LLE+E +Y 
Sbjct: 205 KVGLTPSYPLYIDDVRGWVSDWQMELVTASGVRVIHDYLKTHQPPNSDFSQLLEMELQYS 264

Query: 237 RQEPYITLGRYIHVTAR 253
               YI LGRY+H   R
Sbjct: 265 THPAYIGLGRYVHFITR 281


>UniRef50_Q1ZIA5 SmtA protein n=2 Tax=Gammaproteobacteria RepID=Q1ZIA5_9GAMM
          Length = 256

 Score =  269 bits (688), Expect = 6e-71,   Method: Composition-based stats.
 Identities = 118/256 (46%), Positives = 165/256 (64%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M D NFD IA KF +NIYGTTKG++R A++WQ +   LA +  + LR+LDAGGG G  A 
Sbjct: 1   MIDHNFDGIAHKFLKNIYGTTKGKIRTAVVWQAILDCLALLPQRPLRILDAGGGCGFLAQ 60

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
           K+A  GHQV+LCD+S  ++D AK+  + K  + N+  IHC  Q ++ H++   DLIL HA
Sbjct: 61  KLAAMGHQVVLCDISKVLLDEAKKQMQGKDFAKNVHIIHCPIQQLSEHVDADFDLILNHA 120

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
           VLEW+  P+  LQ L ++L   GV+SLMFYN      HN++  NFD+V+ GM +KK   L
Sbjct: 121 VLEWLECPKQTLQGLLTLLNVNGVMSLMFYNKDAQRFHNLLCANFDFVERGMLRKKVVRL 180

Query: 181 SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP 240
           +P +P     V  WL+E  + ++ KTGVR+ HDYL++  Q    Y  LL +E +Y +QEP
Sbjct: 181 TPTHPLLEKDVQSWLKEVNFYVLQKTGVRIIHDYLKDPTQSVHKYAQLLAMEQKYNQQEP 240

Query: 241 YITLGRYIHVTARKPQ 256
           Y +LGRY H+  +  Q
Sbjct: 241 YASLGRYTHLMIKATQ 256


>UniRef50_B3PES7 SmtA protein n=1 Tax=Cellvibrio japonicus Ueda107
           RepID=B3PES7_CELJU
          Length = 281

 Score =  267 bits (682), Expect = 3e-70,   Method: Composition-based stats.
 Identities = 99/257 (38%), Positives = 159/257 (61%), Gaps = 5/257 (1%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLA----EMGPQKLRVLDAGGGEGQ 57
           QDRNFDD+A++F +NIYG  KG +R A+L +D    L     +    + R+LDAGGG+GQ
Sbjct: 8   QDRNFDDLAKRFRKNIYGGLKGDVRLAVLERDCLACLPIAPFQQPGNRWRILDAGGGQGQ 67

Query: 58  TAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVAS-HLETPVDLI 116
            ++++A  GH+V+LCD+SA+M+  A+       + D +  +H A QD+     +   D +
Sbjct: 68  FSLQLAAAGHEVVLCDISAEMLKLAEAHITHCQLQDRVTLVHAAIQDLPRVIDDHRFDFV 127

Query: 117 LFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKK 176
           + HAV+EW+ DP+S+L  L + L+P G LSL FYN H L+  N++  NF  +++     +
Sbjct: 128 ICHAVMEWMQDPQSLLPCLLNYLKPEGYLSLTFYNLHSLIYKNLLRTNFKKIRSRDYAGQ 187

Query: 177 KRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYC 236
           K +L+P  P  P QV  W+ E   Q++  +G+RVFHDY+ ++ ++      L+E+E  + 
Sbjct: 188 KGSLTPINPLMPEQVLQWVGELPLQLLSHSGIRVFHDYIFDEEKRERDPAGLVEMELLFS 247

Query: 237 RQEPYITLGRYIHVTAR 253
           +QEPY +LGRY H+  +
Sbjct: 248 QQEPYRSLGRYQHLLLQ 264


>UniRef50_Q2SJW8 SAM-dependent methyltransferase n=1 Tax=Hahella chejuensis KCTC
           2396 RepID=Q2SJW8_HAHCH
          Length = 264

 Score =  259 bits (662), Expect = 6e-68,   Method: Composition-based stats.
 Identities = 107/253 (42%), Positives = 161/253 (63%), Gaps = 2/253 (0%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAE-MGPQKLRVLDAGGGEGQTAIKM 62
            NFD++ E+F  NIYGT KG+LR  ++ +DLD  LAE +G    R+LD G G    + ++
Sbjct: 11  HNFDELKERFQNNIYGTPKGRLRLDLINEDLDAHLAERLGEGAWRILDIGCGAAMISGRL 70

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQ-FIHCAAQDVASHLETPVDLILFHAV 121
           A+ GH++ L DLSA+M+  A+   E+ G +   + +     QDV   L+ P DLI+ HAV
Sbjct: 71  AQAGHRLTLTDLSAEMLTAARANLESLGSALACEEWREGPMQDVLPQLQGPYDLIIIHAV 130

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLS 181
           LEW+ DPR  L+   S LRPGGVLSL FYN +GL+  N++ GNF  ++      +K  L+
Sbjct: 131 LEWMDDPRPALELALSKLRPGGVLSLAFYNRNGLIYRNLLQGNFRKLKKNNWYYRKGGLT 190

Query: 182 PDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPY 241
           P  P DP +VY WL +A  +++ K G+R F+D++++   +   YE +LE+E  + ++EPY
Sbjct: 191 PQNPLDPDEVYNWLAQADMRLICKRGIRTFYDFMQKPVARERSYEDVLEMERMHSQKEPY 250

Query: 242 ITLGRYIHVTARK 254
           ++LGRYIHV  +K
Sbjct: 251 LSLGRYIHVLYQK 263


>UniRef50_Q1YTE5 Possible methyltransferase n=1 Tax=gamma proteobacterium HTCC2207
           RepID=Q1YTE5_9GAMM
          Length = 260

 Score =  255 bits (652), Expect = 9e-67,   Method: Composition-based stats.
 Identities = 98/251 (39%), Positives = 152/251 (60%), Gaps = 2/251 (0%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQ-KLRVLDAGGGEGQTAIK 61
           DRNFDD++EKF+R +YG  KG +R A++W+DL   L ++  Q  LR+LD GGG GQ  + 
Sbjct: 7   DRNFDDLSEKFARKVYGGLKGDIRLAVIWRDLLAALPDLEIQAPLRILDIGGGLGQLTVA 66

Query: 62  MAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
           +A+ GHQV+  DLS QM++ A++ A  +GV D + +     Q +        DL++ HA+
Sbjct: 67  LAKLGHQVVYNDLSQQMLEVAQKLALEEGVMDKIIWCQQPYQTLKDQGLERFDLVMSHAL 126

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLS 181
           +EW+A+P  ++  L   L P G+LSL FYN + L+  N++ GNF+ V  G      ++L+
Sbjct: 127 MEWLAEPELLIADLQQYLSPQGLLSLTFYNQNALVYRNLIRGNFN-VLQGEFSAHPKSLT 185

Query: 182 PDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPY 241
           P  P  P  V  W+++AG      +G+RVFHDY+  +    +   A++++E R+  QEP+
Sbjct: 186 PGEPLQPQAVQEWVDQAGLVTDYSSGIRVFHDYVTTQRGGHENASAVIDMELRHSVQEPF 245

Query: 242 ITLGRYIHVTA 252
             LGRYIH   
Sbjct: 246 KWLGRYIHFIC 256


>UniRef50_Q15TU3 Methyltransferase type 11 n=1 Tax=Pseudoalteromonas atlantica T6c
           RepID=Q15TU3_PSEA6
          Length = 252

 Score =  244 bits (623), Expect = 2e-63,   Method: Composition-based stats.
 Identities = 96/254 (37%), Positives = 143/254 (56%), Gaps = 10/254 (3%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRV-LDAGGGEGQTAI 60
           +D+NFD IA+KF +NIYGTTKG+LR  +L   L +    +    L + LDAGGG G+ + 
Sbjct: 6   RDQNFDAIADKFEKNIYGTTKGRLRHELLQYHLRK---NIDFSTLSIALDAGGGTGEMSR 62

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
            + + G  V L D+S + +  AKQ       S  +  IH     +    +   DL++ HA
Sbjct: 63  VLLQSGVNVTLSDISNEALAIAKQKCSE---SSALSVIHSDILGLP---DCEYDLVICHA 116

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
           VLEW+ DP   ++ L S+ + GG  SL F+N    ++ N++ GNFDYV+ GM  K +  L
Sbjct: 117 VLEWLNDPYVNVRKLISMTKIGGYFSLTFFNKDAQMLGNLLYGNFDYVKQGMKVKNRVRL 176

Query: 181 SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP 240
           SP+ P  P  V  +L++    I+   G+R FHDYL++   Q   YE L E E  +  +EP
Sbjct: 177 SPNKPLQPRAVIDFLQKQPVSIISTAGIRCFHDYLKDPTMQLSHYEQLKEAEMAFGDKEP 236

Query: 241 YITLGRYIHVTARK 254
           Y+ LG+Y H+  R+
Sbjct: 237 YMWLGKYFHILMRR 250


>UniRef50_A4XQ92 Methyltransferase type 11 n=17 Tax=Pseudomonas RepID=A4XQ92_PSEMY
          Length = 249

 Score =  244 bits (623), Expect = 3e-63,   Method: Composition-based stats.
 Identities = 95/253 (37%), Positives = 144/253 (56%), Gaps = 6/253 (2%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M DR+FD++A +F+  IYG  KG +R A+L  DL   L +   + LRVLD G G G  ++
Sbjct: 1   MSDRHFDELATRFAEKIYGGAKGAIRLAVLQADLAEALPD---RPLRVLDVGAGLGHMSL 57

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
            +A RGH V L + +  M++ A+Q     G      FI    Q++   L+ P DL+L HA
Sbjct: 58  WLAGRGHDVTLAEPAEPMLEGARQRFAEAG--QRATFIQAPWQELLGRLDQPYDLVLCHA 115

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
           VLEW+A+P ++L  L  +   GG LSL FYN   L+  N++ G+F  ++      + ++L
Sbjct: 116 VLEWLAEPGAILPVLHQLTAKGGWLSLAFYNKDALIYRNLLKGHFRKLRKERFAGEGQSL 175

Query: 181 SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP 240
           +P  P DP ++   L E  WQ+  ++GVRVFHDY+ ++ Q +     LLE+E  + R   
Sbjct: 176 TPQRPLDPRELATQLGEH-WQVESRSGVRVFHDYMPQEFQAKAELIDLLEMELAHRRHPA 234

Query: 241 YITLGRYIHVTAR 253
           +  LGRY+H   R
Sbjct: 235 FAGLGRYLHWICR 247


>UniRef50_Q31JJ3 SAM-dependent methyltransferase n=3 Tax=Piscirickettsiaceae
           RepID=Q31JJ3_THICR
          Length = 259

 Score =  244 bits (622), Expect = 3e-63,   Method: Composition-based stats.
 Identities = 100/258 (38%), Positives = 152/258 (58%), Gaps = 8/258 (3%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIK 61
           QDRNFD + +KF + +Y T KG+ R  +L +DL  +       KL + DAG G  Q +  
Sbjct: 4   QDRNFDKLVDKFEKKVYDTVKGEWRLKLLKEDLTPL---KKGNKLSIWDAGCGFAQISQW 60

Query: 62  MAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
           +AE GH++ LCDLS QM+ RAK       +    +FI    Q+VA  +E   DL+LFHAV
Sbjct: 61  LAESGHRLTLCDLSHQMLLRAKANFAQADLFA--EFIEGPVQEVAKQIEPQ-DLVLFHAV 117

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFD--YVQAGMPKKKKRT 179
           LEW+A P   L+ +   ++PGG LSL+FYN + ++++N + G +   ++       K + 
Sbjct: 118 LEWLAQPEETLKIVTEQVKPGGYLSLLFYNRNSVVINNTLKGKWRLPFILEDAYLNKGKK 177

Query: 180 LSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQE 239
           L+P  P+ P  V  WL++ G++I   TG+RVFHDY+  +  ++   E L+ LE R+CR+ 
Sbjct: 178 LTPPNPQIPEVVCQWLQDWGFKIEIHTGIRVFHDYMTREVLEQSEMEDLMALEYRFCREP 237

Query: 240 PYITLGRYIHVTARKPQS 257
            Y  + RYIH+ A+K  S
Sbjct: 238 TYRNMARYIHILAKKKDS 255


>UniRef50_A4VI82 Methyltransferase, putative n=5 Tax=Pseudomonadaceae
           RepID=A4VI82_PSEU5
          Length = 360

 Score =  241 bits (616), Expect = 1e-62,   Method: Composition-based stats.
 Identities = 93/253 (36%), Positives = 144/253 (56%), Gaps = 6/253 (2%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M DR+FD++A +F+  IYG  KG +R A+L  DL  +L    P+ LRVLD G G G  ++
Sbjct: 112 MSDRHFDELATRFAEKIYGGAKGAIRLAVLQADLAEILP---PRPLRVLDIGAGLGHMSL 168

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
            +A++GH V L + +  M+  A+Q     G      FI    Q+V +H++   DL++ HA
Sbjct: 169 WLAQQGHAVTLAEPAEPMLQGARQQFADAG--QQATFIQAPWQEVQAHVDGRFDLVICHA 226

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
           VLEW+A+P+++L  L  +    G LSL FYN   L+  N++ G+F  +++     ++++L
Sbjct: 227 VLEWLAEPQAILPVLHRLTAADGWLSLAFYNRDALIYRNLLKGHFKKLRSQTYAGERQSL 286

Query: 181 SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP 240
           +P  P DP ++   L    WQ+   +GVRVFHDY+    Q R     L+E+E  Y R   
Sbjct: 287 TPQQPLDPRELAAQLAPH-WQVEFSSGVRVFHDYMPADFQARTEPADLIEMELAYRRHPT 345

Query: 241 YITLGRYIHVTAR 253
           +  LGRY+H   R
Sbjct: 346 FAGLGRYLHWLCR 358


>UniRef50_C5BHU7 SAM-dependent methyltransferase n=1 Tax=Teredinibacter turnerae
           T7901 RepID=C5BHU7_TERTT
          Length = 263

 Score =  241 bits (616), Expect = 2e-62,   Method: Composition-based stats.
 Identities = 94/262 (35%), Positives = 155/262 (59%), Gaps = 8/262 (3%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEM-GPQKLRVLDAGGGEGQTA 59
           MQDRNFDD+A +F RN+YGT KG++R A+L +D      E+     L +LD G G+   +
Sbjct: 1   MQDRNFDDLAPRFKRNVYGTLKGRVRLAVLERDFREYAPELYADSPLDLLDLGAGQAPFS 60

Query: 60  IKMAERGHQVILCDLSAQMIDRAKQAAE--AKGVSDNMQFIHCAAQDVASHL-----ETP 112
           ++ A+ GH+++L D+S++M+  A+ A    A    + +  I    Q +A  L      + 
Sbjct: 61  LQFAQLGHRLVLADISSEMLAGAQLAMADWAAEHRERVHAICHPLQQLAQPLRDMALPSA 120

Query: 113 VDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGM 172
            D+++ HAVLEW+A+P  +   L + L+PGG+LSL FYN +GL   N++  NF       
Sbjct: 121 FDVVICHAVLEWLAEPDRLYSHLANYLKPGGMLSLTFYNINGLAFKNLLRTNFHKFDIDN 180

Query: 173 PKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELE 232
            +  + +L+P +P++P  V   L + G++I+ ++G+RVFHDY+ +  ++    EA++  E
Sbjct: 181 FRSFRGSLTPTHPQEPHHVLRQLSKQGFEIVCRSGIRVFHDYILDPVERNREPEAIVGKE 240

Query: 233 TRYCRQEPYITLGRYIHVTARK 254
             Y R+E +  + RYIHV  RK
Sbjct: 241 LEYSRRESFWPIARYIHVLGRK 262


>UniRef50_UPI0000E11711 methyltransferase type 11 n=1 Tax=Glaciecola sp. HTCC2999
           RepID=UPI0000E11711
          Length = 256

 Score =  240 bits (613), Expect = 3e-62,   Method: Composition-based stats.
 Identities = 103/253 (40%), Positives = 145/253 (57%), Gaps = 8/253 (3%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
           D  FD I++KF++NIYGTTKGQLR A+L   L   L  +     ++LD+G G GQ A   
Sbjct: 10  DHGFDGISDKFAKNIYGTTKGQLRHALLCHHLS-TLNLVNTPPKQILDSGCGLGQMAEFF 68

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
           A+ GH V   D+S++ I  AKQ A+ K +S  + +   + Q V        DLI+ HAVL
Sbjct: 69  ADAGHHVEGMDISSESIAYAKQQAQDKHLS--IDYSVGSLQSVT----KQYDLIINHAVL 122

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSP 182
           EW+ +P + ++ L   L PGG LSL F+N   L   N++ GNFDYV+ G+  KKK  L+P
Sbjct: 123 EWLQEPFAAIELLLKQLVPGGHLSLSFFNKDALTFGNLIYGNFDYVKKGLKVKKKVRLNP 182

Query: 183 DYPRDPAQVYLWLEE-AGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPY 241
             P     V  ++      +I+ + G+R  HDY+R+   Q   YEALL+ E  Y  Q PY
Sbjct: 183 QQPLSVQPVLSFINSLNNIEIIHQAGIRCIHDYMRDLSHQTTHYEALLDAEITYSTQPPY 242

Query: 242 ITLGRYIHVTARK 254
           + LG+Y H+  RK
Sbjct: 243 MWLGKYFHLVLRK 255


>UniRef50_B4RYI5 SAM-dependent methyltransferase n=2 Tax=Alteromonas macleodii
           RepID=B4RYI5_ALTMD
          Length = 247

 Score =  238 bits (607), Expect = 2e-61,   Method: Composition-based stats.
 Identities = 94/253 (37%), Positives = 139/253 (54%), Gaps = 9/253 (3%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIK 61
            D  FD IAEKF+ NIYGTTKG+LR  +L   L   LA    + L+ ++ GGG G     
Sbjct: 3   NDHIFDGIAEKFANNIYGTTKGRLRHTLLCDVLAPYLA----RPLKAIEIGGGTGVMTAH 58

Query: 62  MAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
           +A  GH V+L D S+ ++ +A   A     SDN++  H   Q++        DL++ HAV
Sbjct: 59  IAAMGHDVVLTDASSDVLSKA---APLLNASDNIRIRHQYLQEIDDL--AAYDLVVCHAV 113

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLS 181
           LEW+  P   +  +   ++ G  LSL F+N    L  N + GNFDY+  GM  KK+  L+
Sbjct: 114 LEWLDAPFDAIDFIHKNMKRGARLSLSFFNQDANLFANAIYGNFDYIAKGMKAKKQVRLN 173

Query: 182 PDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPY 241
           P  P    +V  + E  G++++ K G+R FHDY+R+   Q   ++ LL LE +Y +  PY
Sbjct: 174 PKQPLGAMRVVDYCESLGFKVLDKAGIRCFHDYMRDISHQNSKFDELLALERQYHKMPPY 233

Query: 242 ITLGRYIHVTARK 254
           + LG+Y H+   K
Sbjct: 234 LWLGKYFHLILEK 246


>UniRef50_Q21JL0 Methyltransferase type 12 n=1 Tax=Saccharophagus degradans 2-40
           RepID=Q21JL0_SACD2
          Length = 262

 Score =  237 bits (605), Expect = 3e-61,   Method: Composition-based stats.
 Identities = 94/265 (35%), Positives = 142/265 (53%), Gaps = 13/265 (4%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEM-GPQKLRVLDAGGGEGQTA 59
           M DRNFDD+A +F+RNIYG+ KG++R  +L +DL   +        + VLD G G+G  +
Sbjct: 1   MADRNFDDLAPRFARNIYGSHKGRVRLEVLKRDLCDYVPLFQNLAGVEVLDMGAGQGHFS 60

Query: 60  IKMAERGHQVILCDLSAQMIDRAKQAAEA---------KGVSDNMQFIHCAAQDVASHLE 110
           + +AE+G  V LCD+S +M+  AK   +            +  +  F  CA Q +     
Sbjct: 61  LGLAEQGAHVHLCDVSEKMLAMAKVRWQEICEAQAQAGMPIVGSATFTQCALQQLPVK-- 118

Query: 111 TPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQA 170
               L+L HAVLEW+ DPR     L   +  GG LS++ YNAHGL   N++ GNF     
Sbjct: 119 -EYPLVLGHAVLEWLEDPRQGFGYLVDSVATGGYLSVIVYNAHGLAFKNLLRGNFKKFDR 177

Query: 171 GMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLE 230
              K  K +L+P  P  P Q+  W ++   +++G +G+RVF DY+ +K  +    + LL 
Sbjct: 178 NNFKAFKGSLTPISPLTPEQLMQWGKKLKLELVGFSGIRVFQDYILDKSIREADPDGLLV 237

Query: 231 LETRYCRQEPYITLGRYIHVTARKP 255
            E  Y R EP+  + RY+H   ++P
Sbjct: 238 KELEYSRLEPFRNMARYLHFVFKRP 262


>UniRef50_Q1QA01 Methyltransferase type 11 n=4 Tax=Moraxellaceae RepID=Q1QA01_PSYCK
          Length = 295

 Score =  234 bits (596), Expect = 3e-60,   Method: Composition-based stats.
 Identities = 94/262 (35%), Positives = 150/262 (57%), Gaps = 10/262 (3%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMG---PQKLRVLDAGGGEGQTA 59
           DR+FD IA+ F + +YG  KG +R A+L +DL    A+      + LR+LD G G  Q A
Sbjct: 32  DRSFDAIADHFEKKVYGGLKGDIRLAVLRRDLFEYCAQTSHKLGRPLRILDVGAGLAQIA 91

Query: 60  IKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSD---NMQFIHCAAQDVASHLE---TPV 113
           I++A +GH +++ D+SA M+D+A++ A     +D   N+ +  C  Q++   L       
Sbjct: 92  IELATQGHILVINDISANMLDKAQERAAQSSANDEKLNITWYVCPYQELEEKLADKTEKF 151

Query: 114 DLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMP 173
           DLI+ HA+LEW+A+P +V+      L   G LSL FYN       N++ GNF+ +     
Sbjct: 152 DLIMCHALLEWLAEPAAVMDFFDQQLSDNGALSLCFYNPASFDYRNLIMGNFNLLDNTEY 211

Query: 174 KKK-KRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELE 232
           K   K++L+P++P    +V  WL+   +Q +  +G+RVFHDY   K    +  EA++ +E
Sbjct: 212 KADSKKSLTPNHPVAKEEVEAWLQAHDYQTLIASGLRVFHDYSPLKRGGHNDPEAVIRME 271

Query: 233 TRYCRQEPYITLGRYIHVTARK 254
            RY + +PY  LGRY+H+ A +
Sbjct: 272 LRYSQLDPYKWLGRYLHLLATR 293


>UniRef50_Q2NUA0 Putative S-adenosylmethionine-dependent methyltransferase n=1
           Tax=Sodalis glossinidius str. 'morsitans'
           RepID=Q2NUA0_SODGM
          Length = 199

 Score =  228 bits (582), Expect = 1e-58,   Method: Composition-based stats.
 Identities = 114/194 (58%), Positives = 143/194 (73%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           +QDRNFDDIA+KF+RNIYGTTKG++RQA+LWQDL  +LA +  + L +LDAGGGEG+ A 
Sbjct: 2   IQDRNFDDIADKFARNIYGTTKGKIRQAVLWQDLQTLLAHLPQRPLCILDAGGGEGRIAA 61

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
           ++A  GH V+LCDLSAQMI RA+Q A+  GV    + +  A QD+ +HLE   DLIL HA
Sbjct: 62  QLATLGHDVVLCDLSAQMIHRAQQQAKTLGVEQRFRCVQSAIQDIGTHLERHADLILCHA 121

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
           VLEWVA P ++LQ L   L   G LSLMFYN HGL++ NM+ GN  +V AGMPK+KKR+L
Sbjct: 122 VLEWVAQPEALLQILNQCLAGDGALSLMFYNKHGLVIRNMLLGNMAFVAAGMPKRKKRSL 181

Query: 181 SPDYPRDPAQVYLW 194
            PD+P DPA    W
Sbjct: 182 MPDHPCDPADWKKW 195


>UniRef50_Q1QUF1 SmtA protein n=1 Tax=Chromohalobacter salexigens DSM 3043
           RepID=Q1QUF1_CHRSD
          Length = 268

 Score =  225 bits (574), Expect = 1e-57,   Method: Composition-based stats.
 Identities = 100/258 (38%), Positives = 140/258 (54%), Gaps = 9/258 (3%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIK 61
           +DR FD +A+KF+  +YGT +G +R A+L   L R L          LD G G GQ +  
Sbjct: 16  RDRVFDGLADKFAAGLYGTPRGAIRLAVLEHVLPRELPADARP---ALDVGAGLGQMSEW 72

Query: 62  MAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
           +A RGH V L + S  M +RA        V+     +    Q +A     P  LI+ HAV
Sbjct: 73  LARRGHAVTLVEPSRDMRERAMDRVAGLAVTA----LDATWQTLAERAPGPWGLIVCHAV 128

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQ--AGMPKKKKRT 179
           LEW+A+PR     L S+L PGG LS+M +N   L   N+V GN             K++ 
Sbjct: 129 LEWLAEPRDAFARLASLLAPGGYLSVMVFNRDALRFSNVVKGNLAKALDDRLEGLGKRQR 188

Query: 180 LSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQE 239
           L+P  P   AQV  W +EAG  ++  TGVR+FHDYL ++    +  + L+ELE RYC+Q+
Sbjct: 189 LTPISPLTDAQVRAWSQEAGLSLVSVTGVRIFHDYLADRDVSPEKLDQLIELECRYCQQD 248

Query: 240 PYITLGRYIHVTARKPQS 257
           P+  LGRY+H T  KP++
Sbjct: 249 PHWRLGRYLHYTLFKPET 266


>UniRef50_A5EV89 S-adenosylmethionine-dependent methyltransferase n=2
           Tax=Cardiobacteriaceae RepID=A5EV89_DICNV
          Length = 268

 Score =  224 bits (571), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 80/255 (31%), Positives = 133/255 (52%), Gaps = 5/255 (1%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
             F++I + F + IY   KG++R A+L +DL   +    P+ L +LD G G GQ A+  A
Sbjct: 15  HYFEEIGDHFLKQIYYNNKGRIRLAVLKRDLAPFMR--TPKPLEILDIGAGAGQMALWCA 72

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLET-PVDLILFHAVL 122
             GH+V L D S +++ +A++ A+ + ++    FI      +   L     D +L HAVL
Sbjct: 73  AFGHRVTLFDASERLLAQAQKQAQKESLNAQCTFICGEITQMPDVLGARQFDFVLSHAVL 132

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSP 182
           EW+ D   + +     L+P G+LSLM+YN   L     V GNF YV +G+  KK   L+P
Sbjct: 133 EWLEDGAQLFERCQQYLKPNGLLSLMYYNRSALEFIQHVFGNFSYVDSGLVAKKTAKLTP 192

Query: 183 DYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPYI 242
            YPR    V   L      +  ++G+R F+DY++ + +  +  E+++  E     +  ++
Sbjct: 193 KYPRSSDWVAAQLGA--LPLKKQSGIRCFYDYMKPEDRAANSIESIIAHELSLSLRREFL 250

Query: 243 TLGRYIHVTARKPQS 257
            + RYIH   ++  S
Sbjct: 251 PVARYIHEIRQRTIS 265


>UniRef50_Q1N5H2 SAM-dependent methyltransferase n=1 Tax=Bermanella marisrubri
           RepID=Q1N5H2_9GAMM
          Length = 258

 Score =  222 bits (566), Expect = 8e-57,   Method: Composition-based stats.
 Identities = 91/258 (35%), Positives = 142/258 (55%), Gaps = 8/258 (3%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
           DRNF+ ++ +F   IYGT KGQ+R A+L +DL   + +     L +LD G G+GQ +  +
Sbjct: 2   DRNFNGLSNRFKNQIYGTLKGQMRLALLEKDLSPYIEQT--HALNILDCGAGQGQFSSML 59

Query: 63  AERGHQVILCDLSAQMIDRAKQA-AEAKGVSDNMQFIHCAAQDVASHL-----ETPVDLI 116
           A+ GH ++L D+S +M+  A+   AE    +   Q I    Q +   L      T  DL+
Sbjct: 60  AQHGHSLVLNDVSDEMLAMAQANLAELAPDNQTHQMITAPLQSLNEELHTRALPTQYDLV 119

Query: 117 LFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKK 176
           L HAVLEW+ +P + ++ L   ++  G+LSLMFYN H ++  N++ G++   Q       
Sbjct: 120 LNHAVLEWLHEPFAAIEQLALWVKSDGILSLMFYNLHAIVWRNLMNGSWQRAQNTHFHHD 179

Query: 177 KRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYC 236
           K  L P  P +PA V   +E  G+ I    G+R  HD++  + ++R   E  +ELE+   
Sbjct: 180 KNNLMPQNPLNPADVVEKIESLGFSIELHRGIRCVHDHMFVEMRKRKTLEEFVELESDIG 239

Query: 237 RQEPYITLGRYIHVTARK 254
            + PY  LGRY+H+ ARK
Sbjct: 240 LKAPYRDLGRYVHIVARK 257


>UniRef50_B5L6J9 Methyltransferase n=1 Tax=Micromonospora chalcea RepID=B5L6J9_MICCH
          Length = 263

 Score =  184 bits (467), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 70/262 (26%), Positives = 128/262 (48%), Gaps = 11/262 (4%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           +++  FD+   +F +    T  G+LR +++  ++ R    +G + LRVLD  GG G+ A+
Sbjct: 5   IENALFDERLAQF-QQWQKTPWGRLRYSVVEANVAR---HLGDRPLRVLDVAGGNGRDAV 60

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETP-VDLILFH 119
            +A RGH V + D +   +  A++ A  +GV++ ++     A DV         DL+L H
Sbjct: 61  PIAARGHHVTVLDSAPVSLAMAQRLAADEGVAERIEIREGDAHDVPELFAGQEFDLLLCH 120

Query: 120 AVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAG-NFDYVQAGMPKKKKR 178
            +L++VADP  V++ L  VL+PGG LS++  NA+ + +   V   + D     +  + K+
Sbjct: 121 NLLQYVADPAVVIRGLVKVLKPGGSLSVVGPNAYAVPLEAAVRELDLDAALRAVTARTKQ 180

Query: 179 TLSPDY---PRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDC--YEALLELET 233
                         Q+   L ++G +I+G  GV    + + +   + D   +  L +LE 
Sbjct: 181 VPVYGRDVAVLTADQIGADLRDSGLEIVGHYGVINICNVIADNDVKSDPEFFARLEKLEL 240

Query: 234 RYCRQEPYITLGRYIHVTARKP 255
               + PY    R  H+  ++P
Sbjct: 241 ALADRMPYPLTARNFHLVGQRP 262


>UniRef50_B3TMR6 SAM-dependent methyltransferase n=1 Tax=Actinomadura kijaniata
           RepID=B3TMR6_9ACTO
          Length = 260

 Score =  178 bits (452), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 70/258 (27%), Positives = 121/258 (46%), Gaps = 11/258 (4%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
           +FD     F +    T  GQLR +++  +L R    +G + LRVLD  GG G+ A+++A 
Sbjct: 6   HFDHRLANF-QQWQETPWGQLRYSVVEANLAR---HLGDRPLRVLDVAGGNGRDAVRLAL 61

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVAS-HLETPVDLILFHAVLE 123
           RGH V + D +   +  A++ A  +GV+D ++     A DV     +   DL+L H +L+
Sbjct: 62  RGHHVTVLDSAPISLAGAEELAAERGVADRIEVREGDAHDVPELFPDQDFDLLLCHNLLQ 121

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAG-NFDYVQAGMPKKKK--RTL 180
           +V D   V++ +   LRPGG+LS++  NA  + +   V   + D     +    K  +  
Sbjct: 122 YVPDRAVVVRAIARRLRPGGLLSVVGPNAVAVPLEAAVRELDLDAALRAVDSSTKPNQVY 181

Query: 181 SPDYP-RDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQ--RDCYEALLELETRYCR 237
             D P     ++     +AG  ++G  GV      + +   +   + +  L +LE     
Sbjct: 182 GADVPVLTADEIGGHFRDAGLDVVGHHGVLSVCHLIADNEIKYDPEFFARLEKLEHTLAE 241

Query: 238 QEPYITLGRYIHVTARKP 255
           + PY +  R  H+  R P
Sbjct: 242 RAPYPSTARMFHLVGRLP 259


>UniRef50_D1V817 Methyltransferase type 12 n=2 Tax=Frankia RepID=D1V817_9ACTO
          Length = 276

 Score =  178 bits (452), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 70/259 (27%), Positives = 121/259 (46%), Gaps = 17/259 (6%)

Query: 8   DIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGH 67
            +A  + +    T +G +RQ ++ + L   L  +     R+LD GGGEG  A  +A  G+
Sbjct: 21  ALAPGY-QAHTATLRGAVRQRLVTRAL---LTHLPTPPGRILDVGGGEGTQARALARLGY 76

Query: 68  QVILCDLSAQMIDRAKQAA--EAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV 125
           +V +CD   +M+ +A +        V D +  +H    D AS +    D +L H VL ++
Sbjct: 77  EVTICDPDPEMLRQADERLSGADAAVRDRITLVHGDGHDAASLVGGGWDGVLCHGVLMYL 136

Query: 126 ADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGM---PKKKKRTLS- 181
            DP ++L  L  V   GGV+S++  NA  L +   + G +    + +   P+    T++ 
Sbjct: 137 TDPAALLHVLADVTGAGGVISVVGKNATALALRAGLQGRWRDTLSLLDEEPRAAAGTVTE 196

Query: 182 ------PDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRY 235
                 P    DP Q+   L  AG + +   G+RV  D+L +     D  + ++E E R 
Sbjct: 197 IGNLGVPSRGDDPHQIRDLLSAAGTEPLAWYGIRVLTDHLGDTPPGPD-LDTVVEAEWRA 255

Query: 236 CRQEPYITLGRYIHVTARK 254
             ++PY  + R  H+  R+
Sbjct: 256 GERDPYRQVARLYHLIHRR 274


>UniRef50_A4BJS3 Putative SmtA protein n=1 Tax=Reinekea blandensis MED297
           RepID=A4BJS3_9GAMM
          Length = 229

 Score =  177 bits (450), Expect = 3e-43,   Method: Composition-based stats.
 Identities = 74/228 (32%), Positives = 110/228 (48%), Gaps = 2/228 (0%)

Query: 28  AILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGH-QVILCDLSAQMIDRAKQAA 86
            ++     +VL     +  +VLDAGGG GQ +    E+G   V   D+S QM+  A ++ 
Sbjct: 2   RLVDALYRKVLPLDQLENWKVLDAGGGLGQMSHWFLEQGVTSVDYLDVSEQMVTAATESL 61

Query: 87  EAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLS 146
           +    +  +     +  D++    +  D +  HAVLEW+  P +V+  L   +RPGG L 
Sbjct: 62  QEYYEAGQLNASVGSVTDLS-EWPSDYDFVNVHAVLEWLEKPETVVPILCDRVRPGGYLG 120

Query: 147 LMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKT 206
           LM YN H L+M +M+ G      +G     KR L+P  P DP  V   L+  G  I+ + 
Sbjct: 121 LMVYNRHMLMMRHMMRGTLKRAMSGNMAGDKRGLTPISPMDPQAVAKDLQACGMTILCQA 180

Query: 207 GVRVFHDYLREKHQQRDCYEALLELETRYCRQEPYITLGRYIHVTARK 254
           G+R F D   +   +    EA+ + E   C Q PY  LGRY    ARK
Sbjct: 181 GIRSFSDLTEKAVLEWYTEEAVFDAEQALCEQRPYCDLGRYTLFIARK 228


>UniRef50_A3TKD6 Putative methyltransferase n=1 Tax=Janibacter sp. HTCC2649
           RepID=A3TKD6_9MICO
          Length = 258

 Score =  172 bits (435), Expect = 1e-41,   Method: Composition-based stats.
 Identities = 72/242 (29%), Positives = 109/242 (45%), Gaps = 13/242 (5%)

Query: 26  RQAILWQDLDRVLAEMG---PQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRA 82
           R A +W  +D V+        + LRV+D GGG G  A+ +A  GH V + D S   +   
Sbjct: 18  RTAAMWAAVDEVVRARSAELERPLRVIDLGGGTGGLAVPLAVAGHDVTVVDPSPDALASL 77

Query: 83  KQAAEAKGVSDNMQFIHCAAQDVASHL--ETPVDLILFHAVLEWVADPRSVLQTLWSVLR 140
           ++ A     S  +  +   A  + S +  + P DL+L H  LE+V DP++ L  +  VL 
Sbjct: 78  RRRAAEAQASSRVSAVQGDADTLESLVGRDRP-DLVLCHGTLEYVDDPQATLAQIAGVLA 136

Query: 141 PGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPR---DPAQVYLWLEE 197
           PGG+LSL+       ++   +AG F    A + +   R    D      D A V   +E 
Sbjct: 137 PGGILSLVVPQRSAAVIARALAGQFVQALAALDRPDGRWGDADPVPRRFDRAGVVGLIEA 196

Query: 198 AGWQIMGKTGVRVFHDYLREKHQQRDC-YEALLELETRYCRQEPY---ITLGRYIHVTAR 253
           +G  I G  G+R+F D +       D    ALL+LE        +     LG  +HV A 
Sbjct: 197 SGLTITGAHGIRIFSDLVPSALVDSDADRAALLDLERAVAAHPEFAVLADLGTSLHVIAS 256

Query: 254 KP 255
           +P
Sbjct: 257 RP 258


>UniRef50_A3TLQ5 S-adenosylmethionine-dependent methyltransferase n=1 Tax=Janibacter
           sp. HTCC2649 RepID=A3TLQ5_9MICO
          Length = 259

 Score =  172 bits (435), Expect = 1e-41,   Method: Composition-based stats.
 Identities = 66/245 (26%), Positives = 119/245 (48%), Gaps = 11/245 (4%)

Query: 19  GTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQM 78
            +  G+LR A++   +D  +AE G + LR+LD GG +G   +  A RGHQ+ + D +   
Sbjct: 16  ASPWGRLRFALIGDAIDEAIAEFGDRTLRILDVGGADGFETLPYAIRGHQLTVADPAEGF 75

Query: 79  IDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVA--DPRSVLQTLW 136
            DR ++AAE  GVSD ++++    +++    +T  D+++ H VL +       + + TL 
Sbjct: 76  FDRGREAAEQLGVSDRVRWVSAGLEELPMAGDTAYDVVVCHFVLHYRPAGSLGADVATLS 135

Query: 137 SVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDP-----AQV 191
            +  P GV+S+   N  GL++  +        +A + +  +   S  +  D       +V
Sbjct: 136 RLTAPDGVISIACPNEAGLVLRTLTREGPAAARAELDETTQ--FSHTFGHDSQKVGREEV 193

Query: 192 YLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDC--YEALLELETRYCRQEPYITLGRYIH 249
              L E G       GVR+ +D +     + D   ++ LL LE   CR++PY  +     
Sbjct: 194 AAALHENGLVETEWMGVRIANDLIVHDEMKHDPVYFQQLLALERDLCRRDPYRGIAALWQ 253

Query: 250 VTARK 254
           +TA++
Sbjct: 254 LTAKR 258


>UniRef50_B9K8U5 Ubiquinone/menaquinone biosynthesis methyltransferase-related
           protein n=6 Tax=Thermotogaceae RepID=B9K8U5_THENN
          Length = 258

 Score =  170 bits (430), Expect = 5e-41,   Method: Composition-based stats.
 Identities = 61/258 (23%), Positives = 112/258 (43%), Gaps = 25/258 (9%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
            +  IA+++  ++Y T K +L   +    +   L+E      RVLD GGG G+ ++ + E
Sbjct: 8   YYSRIAKEYD-SMYETPKWRLYHRL----IQSFLSEHLKVPCRVLDLGGGTGRWSLFLLE 62

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA-VLE 123
           RG  V L D S +M+  A    E KGV    +F+   A+D+        D +L    VL 
Sbjct: 63  RGFDVTLVDPSEEMLKIA----EKKGVK---KFLKARAEDLPFSSH-SFDTVLAMGDVLS 114

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPD 183
           +V +       +  VL+PGG+L     N +  L H +    ++ +   +   K +T+   
Sbjct: 115 YVENKVKAFSEIARVLKPGGLLIATVDNFYTFLQHMIEENTWEKIPRFL---KTQTIEVG 171

Query: 184 YPRDPAQVYLWLEE-----AGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQ 238
                   Y +  E      G+  +   G+ VF DY  ++ ++++    + ELE  + R 
Sbjct: 172 NTLFSFNSYAFRPEDIESIEGFDTIEVRGIGVF-DYSEDQVRKKEDL--IFELEKEFSRD 228

Query: 239 EPYITLGRYIHVTARKPQ 256
              +    ++    +K +
Sbjct: 229 RAILWRAEHVFFVLKKKE 246


>UniRef50_D2SA73 Methyltransferase type 11 n=1 Tax=Geodermatophilus obscurus DSM
           43160 RepID=D2SA73_9ACTO
          Length = 252

 Score =  168 bits (426), Expect = 2e-40,   Method: Composition-based stats.
 Identities = 70/240 (29%), Positives = 100/240 (41%), Gaps = 14/240 (5%)

Query: 26  RQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQA 85
           R   +W  LD ++A    + L+VLD GGG G  A+ +A  GH V + D SA  +    + 
Sbjct: 17  RAVAVWAALDPLVA--AGRPLQVLDVGGGSGNFAVPLARLGHDVTVVDPSADALATLNRR 74

Query: 86  AEAKGVSDNMQFIHCAAQDV------ASHLETPVDLILFHAVLEWVADPRSVLQTLWSVL 139
           AE  GV   ++ +      +          E   DL L H+VLE V DP + L+ L   L
Sbjct: 75  AENAGVGARVRGVQGDGDQLHQVVPAGETGEGSYDLALCHSVLEVVDDPAATLRELARAL 134

Query: 140 RPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPR----DPAQVYLWL 195
           RPGG  S+   N  G ++   VAG+     A +  +         P      P  +   +
Sbjct: 135 RPGGTASVASANRAGAVLARAVAGHPVEALALLEDRDPAPRRARRPARRRFSPDDLITLV 194

Query: 196 EEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPYITLGRYIHVTARKP 255
           E AG Q     GV V  D L          EA+  LE       PY  +   +H+ A +P
Sbjct: 195 EAAGLQPGTWRGVSVVSDLLDVTSGA--DPEAVRRLELALAGSSPYRDVAAGLHLLATRP 252


>UniRef50_A4FIW0 Methyltransferase n=3 Tax=Actinomycetales RepID=A4FIW0_SACEN
          Length = 272

 Score =  168 bits (426), Expect = 2e-40,   Method: Composition-based stats.
 Identities = 61/264 (23%), Positives = 114/264 (43%), Gaps = 13/264 (4%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M D  +  +A++F+   Y + KG++R  +L Q L   L  + P    VLD GGG G  + 
Sbjct: 1   MDDDTWAGLADQFADGAYASVKGRVRTYVLHQQL---LEHLPPPPAPVLDVGGGAGHQSF 57

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKG--VSDNMQFIHCAAQDVASHLET-PVDLIL 117
            +A+ G+ V L D S+ M+D+A+Q  +         +  +    ++    +       +L
Sbjct: 58  PLAQAGYDVTLLDPSSAMLDKARQRLDRLPDEAQRRVTLLEADGENADEAVNGRRFAAVL 117

Query: 118 FHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKK 177
            H VL +   P  ++  L      GG++S+M  NA+ + +   +   +D   A    + +
Sbjct: 118 CHGVLGYQEQPEPLVDQLCRCAAAGGIVSIMAGNANAMAVRPALERRWDDALASFDARGE 177

Query: 178 RTL--SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEA-----LLE 230
             +   P       ++   +   G + +   GV +F D+L     + D  ++        
Sbjct: 178 IGVLGVPTRADTVEELSELVRSRGVEPLRWYGVWLFVDWLDFSGAELDPGDSEQVAAAAA 237

Query: 231 LETRYCRQEPYITLGRYIHVTARK 254
           +E    R++PY  L R  H+  RK
Sbjct: 238 VELEAGRRDPYRGLSRVFHLVGRK 261


>UniRef50_B4V3L4 Methyltransferase n=17 Tax=Streptomyces RepID=B4V3L4_9ACTO
          Length = 235

 Score =  167 bits (423), Expect = 4e-40,   Method: Composition-based stats.
 Identities = 70/232 (30%), Positives = 109/232 (46%), Gaps = 9/232 (3%)

Query: 32  QDLDRVLAEMGP--QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAA--E 87
           + +D  +A+  P  Q+LRVLD G G+G  A+++A  GH+V   +    M+D A+ A   E
Sbjct: 3   RQVDEQIAQRFPVGQRLRVLDVGMGQGTQALRLARAGHKVTGLEKDPGMLDVARAALAGE 62

Query: 88  AKGVSDNMQFIHCAAQDV-ASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLS 146
             G+ D ++ I    ++  A  L    D++L H VL +V +P ++L  L  +L PGG+LS
Sbjct: 63  PAGIQDRVELIEGDGRETGAHFLPGSFDIVLCHGVLMYVPEPDAMLAGLARMLAPGGLLS 122

Query: 147 LMFYNAHGLLMHNMVAGNFDYVQAGMPKKK-KRTLSPDYPRDP-AQVYLWLEEAGWQIMG 204
           L+  N   L M   + G++    A          L  D   D  + +   L   G  +  
Sbjct: 123 LLVRNGDALAMRPGLDGDWSGALAAFDTTDYTNRLGLDVRADRLSGLTATLSGIGAPLQS 182

Query: 205 KTGVRVFHDYLR--EKHQQRDCYEALLELETRYCRQEPYITLGRYIHVTARK 254
             GVRVF D     E+    D  E LL  E R  R +PY  +   +H+   +
Sbjct: 183 WYGVRVFTDGTEAGEQLPPEDELERLLAAEERAGRSDPYRGVAALLHLCGVR 234


>UniRef50_C7QBJ1 Methyltransferase type 12 n=15 Tax=Actinomycetales
           RepID=C7QBJ1_CATAD
          Length = 263

 Score =  166 bits (420), Expect = 9e-40,   Method: Composition-based stats.
 Identities = 75/237 (31%), Positives = 109/237 (45%), Gaps = 11/237 (4%)

Query: 29  ILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEA 88
           +LWQ L  VL   GP+   VLD GGG G  A+ +AE GH+V + D S   +   ++ A  
Sbjct: 30  VLWQALRTVLDASGPRD--VLDVGGGTGGFAVPIAELGHRVTVVDPSPDALAALERRAAE 87

Query: 89  KGVS-DNMQFIHCAAQDVASHLE-TPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLS 146
            GV  + ++ +      +  H+E   VDL+L H VLE   DP + L T+  VLRPGGV+S
Sbjct: 88  SGVPKEALRAVQGDLAGLLEHVEPGSVDLVLCHGVLEMADDPAAGLATVADVLRPGGVVS 147

Query: 147 LMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPR----DPAQVYLWLEEAGWQI 202
           L+  N    ++   + G+F   +  +     R      P     D  Q+   L EA   +
Sbjct: 148 LLAANRTAAVVARALGGHFAEARRALADPTGR-FGAQDPLAARFDEEQLSRLLREARLTV 206

Query: 203 MGKTGVRVFHDYLREKHQQRDCYEA--LLELETRYCRQEPYITLGRYIHVTARKPQS 257
               GVRVF D +       D   A  L  LE     +  +  +   +H+ ARK  S
Sbjct: 207 QSVHGVRVFTDLVPGALVDADPQAASDLAALEAAVADRPEFRAVAGRLHLLARKIAS 263


>UniRef50_C0ZNJ7 Putative methyltransferase n=1 Tax=Rhodococcus erythropolis PR4
           RepID=C0ZNJ7_RHOE4
          Length = 274

 Score =  165 bits (419), Expect = 9e-40,   Method: Composition-based stats.
 Identities = 71/263 (26%), Positives = 117/263 (44%), Gaps = 19/263 (7%)

Query: 12  KFSRNIYG------TTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           KF +++        +  G+LR  +   +LD  +   G   LRVLD GGG+G  +I +A  
Sbjct: 7   KFDKSVDARAHWQSSPWGRLRYTVARANLDTYVG--GRSGLRVLDLGGGDGLESILLARN 64

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLE-TPVDLILFHAVLEW 124
           G+QV L D S  M+D A   A+A GVS +M F++    D+   +     D++L H VL++
Sbjct: 65  GNQVTLVDSSPAMLDIASGRADAAGVSASMTFVNSEVLDLPRSIATGSFDVVLLHNVLQY 124

Query: 125 VADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDY 184
           +      L  + + L  GG+ S++  N     +        D  +A     + R  S  +
Sbjct: 125 LPQGIGALPAVTAPLADGGIFSVISINKFSEPIAAAAR-RADPTEALNLLGESRYRSVTF 183

Query: 185 PRD-----PAQVYLWLEEAG-WQIMGKTGVRVFHDYLREKHQQRDC--YEALLELETRYC 236
             D        +   +E  G +  +   G+R F D++    ++ D   Y AL  LE    
Sbjct: 184 DSDLTMFAAGDIIDAIEATGDFGDVNHYGIRCFSDFIAADDEKWDPEFYSALEALELAST 243

Query: 237 RQEPYITLGRYIHVTARKPQSKD 259
            + PY+   R   +  R+  SKD
Sbjct: 244 ARWPYMHTARLFQIIGRR-ASKD 265


>UniRef50_A8M0L9 Methyltransferase type 12 n=1 Tax=Salinispora arenicola CNS-205
           RepID=A8M0L9_SALAI
          Length = 269

 Score =  164 bits (415), Expect = 3e-39,   Method: Composition-based stats.
 Identities = 71/269 (26%), Positives = 123/269 (45%), Gaps = 17/269 (6%)

Query: 1   MQDR------NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGG 54
           M DR       FD  AE +      T  G+LR  ++   +DR +  +     RVLDAGG 
Sbjct: 1   MSDRPQATPEVFDRRAEAWD-AWQETPWGRLRYRLVAHTVDRAVRRLS-GTCRVLDAGGA 58

Query: 55  EGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASH---LET 111
           +G  ++++A+RGH V + D +  ++ RA+  A A GV   ++ +     +V       E 
Sbjct: 59  DGADSLRLAQRGHHVTIVDHAPALLARARARARAAGVDHLVRTVCAGVDEVPELRRTGEV 118

Query: 112 PVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAG 171
             DL+L H VL ++ D  + +  L + +RPGG++S++  N    L+   V  +      G
Sbjct: 119 GFDLVLCHNVLHYLPDTPAAVAGLATAVRPGGLISVLAPNPAMDLLAIAVRRSSPAEAFG 178

Query: 172 MPKKKKR---TLSPDYPR-DPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDC--Y 225
           +   +     T   D  R +   V   LE++G  +  + G+R   D +     +     +
Sbjct: 179 LLDAEALFSETFEHDMLRLEAEDVAAALEKSGCTVTDRFGIRCATDLIANDELKHTPAFF 238

Query: 226 EALLELETRYCRQEPYITLGRYIHVTARK 254
             L  LE   C +EPY+ + R+  + A +
Sbjct: 239 ADLERLELALCDREPYLRMARFWQLLATR 267


>UniRef50_C5CH90 Methyltransferase type 11 n=1 Tax=Kosmotoga olearia TBF 19.5.1
           RepID=C5CH90_KOSOT
          Length = 256

 Score =  163 bits (412), Expect = 7e-39,   Method: Composition-based stats.
 Identities = 56/261 (21%), Positives = 115/261 (44%), Gaps = 23/261 (8%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
            +DD+A ++          +    +L+ ++ R L        ++LD G G G+ AI++A+
Sbjct: 7   YYDDVASRYDYM------YEEPYWVLYHEIVRKLINEHQVNGKILDLGTGTGRWAIELAD 60

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA-VLE 123
           +G ++I  D + +M+  A++ A+  GV  N++F   + + +        D +L    VL 
Sbjct: 61  KGMEIIAVDPAEKMLKVAEEKAKLYGV--NIKFTKASGEALPFES-NTFDFVLAMGDVLS 117

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPD 183
           +   P  VL+ +  VL+  G L     NA+  L H+ ++    Y      +++++    D
Sbjct: 118 YAKSPEKVLEEIKRVLKNRGKLLATVDNAYAFL-HDFISQGETYNARRFIERERKVPIGD 176

Query: 184 ----------YPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELET 233
                      P  P  +   ++ A  Q++    + VF  Y  EK  +    + +++ E 
Sbjct: 177 SSVSEKHFYTRPYFPEDIEKLVKNASMQLIDIAALVVFAPYSEEKLARN--LDRIVQWEL 234

Query: 234 RYCRQEPYITLGRYIHVTARK 254
            +CR++       ++   ARK
Sbjct: 235 EFCRRKELFGRAEHLFFCARK 255


>UniRef50_Q46F96 Ubiquinone/menaquinone biosynthesis methyltransferase n=2
           Tax=Methanosarcina RepID=Q46F96_METBF
          Length = 259

 Score =  161 bits (407), Expect = 2e-38,   Method: Composition-based stats.
 Identities = 57/231 (24%), Positives = 100/231 (43%), Gaps = 24/231 (10%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
           + + D   KF     G   G + ++ +W  L  +   +GP    VLD G G G  A+ +A
Sbjct: 17  KKYWDYGSKFYDTAPG--NGGVEESQMWSKL--LSGAIGPGPKNVLDVGSGTGIIAMYLA 72

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
           E GH+V   D S  M+D A++ A  KG   N++F+    +++    +   D I    VL 
Sbjct: 73  ELGHRVTAVDFSEGMMDVARKKALEKG--ANIRFMEMDVENLNFE-DETFDFITARYVLW 129

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMF--YNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLS 181
            ++ P   ++    V++PGG + ++   +   GLL        F+Y      K  K   +
Sbjct: 130 TMSHPEKAVKEWVRVVKPGGRIVIIDGKWVTKGLLP---CISAFNYHIYRFIKYGKNPFT 186

Query: 182 PDYPRD------------PAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQ 220
            DY +D              QV  ++ +AG   +  T +++  D  R++  
Sbjct: 187 YDYKKDINVSLPNPHGVESKQVVEYMSKAGLDDIAVTDLKIIRDIQRKRLP 237


>UniRef50_D1VJQ5 Methyltransferase type 12 n=1 Tax=Frankia sp. EuI1c
           RepID=D1VJQ5_9ACTO
          Length = 296

 Score =  160 bits (404), Expect = 6e-38,   Method: Composition-based stats.
 Identities = 75/265 (28%), Positives = 115/265 (43%), Gaps = 26/265 (9%)

Query: 19  GTTKGQLRQAILWQDLDRVLAEMGPQKLR--------VLDAGGGEGQTAIKMAERGHQVI 70
              +   R A +W+ L  VLA                V+DAGGG G  A+ +AERGH+V+
Sbjct: 30  AAERADPRHAAVWRALTDVLAAGPAGTGAGPAGAGLTVVDAGGGSGGFAVPLAERGHRVL 89

Query: 71  LCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVAS------HLETPVDLILFHAVLEW 124
           + D S   +    + A   GV+  +        ++++            DL+L HAVL+ 
Sbjct: 90  VVDPSQDALAALARRAADAGVAARVTGRQGDLSELSAVVGPDLAAAGGADLLLCHAVLDR 149

Query: 125 VADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGM-----PKKKKRT 179
           V DPR  L T+  VLRPGG LSL+     G ++   +AG FD     +     P   +R 
Sbjct: 150 VDDPRRALATVLRVLRPGGWLSLLVPGRAGTVLARALAGRFDEAAQALAGPYPPAPGRRL 209

Query: 180 LSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLR-------EKHQQRDCYEALLELE 232
               +  D  ++   +  AG +++   GVRV  D          E+       E L +LE
Sbjct: 210 AGETHRFDTDEIVGLVRAAGAEVVAVHGVRVLTDLATPPAGGGDEREPAAGWAERLADLE 269

Query: 233 TRYCRQEPYITLGRYIHVTARKPQS 257
                + PY  L   +HV AR+ ++
Sbjct: 270 AAVATRPPYRDLAAQLHVLARRTEA 294


>UniRef50_UPI0001B4EB31 methyltransferase n=1 Tax=Streptomyces sp. C RepID=UPI0001B4EB31
          Length = 262

 Score =  156 bits (396), Expect = 5e-37,   Method: Composition-based stats.
 Identities = 66/256 (25%), Positives = 121/256 (47%), Gaps = 11/256 (4%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           FD +   ++ +   + +G+LR  ++ +   R+LAE+     R+LD G G G+  +++A  
Sbjct: 7   FDSVGAAYAAH-SDSARGRLRHDLVER---RLLAELPAAPARILDVGCGNGEMTLRLAAA 62

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKG-VSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
           G++V   D +A M+  A     A+  ++D +Q ++     ++     P D +  H VL +
Sbjct: 63  GYRVTGVDPAATMLAAAADRLAARPELADRVQLVNAGLDSLS-LDGKPFDGVCCHGVLMY 121

Query: 125 VADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLS--- 181
           + DP   +  L  ++ PGG+LS++  N+  + +   +AG+ +     +  +  R++    
Sbjct: 122 LDDPGEAVVRLAGLVAPGGLLSILAKNSRAVGVREALAGDSETACRLIVSQADRSVGNLG 181

Query: 182 -PDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREK-HQQRDCYEALLELETRYCRQE 239
                 DP  +     E G       GVR+FHD+  +        Y A LELE     + 
Sbjct: 182 RETRGDDPDALDRLAAEHGLSPQPWQGVRIFHDHFDDTWAPDPAAYAAALELEWAASSRS 241

Query: 240 PYITLGRYIHVTARKP 255
           PY  LG  +H  AR+P
Sbjct: 242 PYRDLGHLVHTLARRP 257


>UniRef50_C9NJ50 Methyltransferase type 12 n=8 Tax=Streptomyces RepID=C9NJ50_9ACTO
          Length = 252

 Score =  156 bits (394), Expect = 9e-37,   Method: Composition-based stats.
 Identities = 65/244 (26%), Positives = 110/244 (45%), Gaps = 10/244 (4%)

Query: 21  TKGQLRQAILWQ----DLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSA 76
            +  LR A++W+     L+R +   G + L VLD GGG G  A+ +A  GH+V + D S 
Sbjct: 7   PRASLRTAVVWEVLKDALERRVKATGREALDVLDTGGGTGNFAVPVARLGHRVTVVDPSP 66

Query: 77  QMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLE-TPVDLILFHAVLEWVADPRSVLQTL 135
             +   ++ A+  GV+D ++ +      +   ++    D +L H VLE+V DP   ++  
Sbjct: 67  NALFALERRADEAGVADRVRGVQGDILGLFEVVDRAGYDAVLCHGVLEYVDDPAEGVRNA 126

Query: 136 WSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPR---DPAQVY 192
              LRP G LSL+     G ++   +AG+F   +  +     R  + D         Q+ 
Sbjct: 127 VDALRPSGALSLLGAGLGGAVLARALAGHFAEARQALTDPDGRWGAGDPVPRRFTADQLT 186

Query: 193 LWLEEAGWQIMGKTGVRVFHDYLRE--KHQQRDCYEALLELETRYCRQEPYITLGRYIHV 250
             ++ AG ++    GVRVF D +       +    E LL LE        + ++   +HV
Sbjct: 187 GLVDAAGVEVGAVHGVRVFADLVPGVLVDTEPGAMEELLRLEAAVAELPAFHSVATQLHV 246

Query: 251 TARK 254
              K
Sbjct: 247 LGEK 250


>UniRef50_Q2JD64 Methyltransferase type 11 n=2 Tax=Frankia RepID=Q2JD64_FRASC
          Length = 270

 Score =  155 bits (393), Expect = 1e-36,   Method: Composition-based stats.
 Identities = 72/247 (29%), Positives = 108/247 (43%), Gaps = 16/247 (6%)

Query: 21  TKGQLRQAILWQDLDRVLA-------------EMGPQKLRVLDAGGGEGQTAIKMAERGH 67
           T   LRQA +W  L  VL                      ++DAGGG G  A+ +A  G+
Sbjct: 6   TGADLRQAAIWHGLRTVLPGSAAGVPAWSVAPTATAIPPIIVDAGGGSGGFAVPLAVEGY 65

Query: 68  QVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHL-ETPVDLILFHAVLEWVA 126
            VI+ D S   +   ++ A+ +GV+D +        D+   +     DL+L H+VL+ V 
Sbjct: 66  LVIVVDPSPDALAALRRRADERGVADRVTAEQGDLADLTGIVGAETADLLLCHSVLDVVD 125

Query: 127 DPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPR 186
           DP + L     VLRPGGVLSL+       ++   +AG F+  QA +  +           
Sbjct: 126 DPEAALAGALRVLRPGGVLSLVVAGRAATVLARALAGRFEQAQAVLTGQGAGAPRTPAGF 185

Query: 187 DPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEA--LLELETRYCRQEPYITL 244
             A++   +  AG  ++   GVRVF D +       D + A  LL LE      EP+  L
Sbjct: 186 TTAEIVALVNAAGADVVDVHGVRVFADLVPGARVDSDPFTAQRLLRLELAAAALEPFRDL 245

Query: 245 GRYIHVT 251
              +HV 
Sbjct: 246 AAQLHVL 252


>UniRef50_C9R8S5 Methyltransferase type 11 n=1 Tax=Ammonifex degensii KC4
           RepID=C9R8S5_AMMDK
          Length = 225

 Score =  154 bits (390), Expect = 2e-36,   Method: Composition-based stats.
 Identities = 47/206 (22%), Positives = 85/206 (41%), Gaps = 22/206 (10%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           FD  A  +  + Y T +G+L   + W+ L ++L+    +  +VLDAG G G  +  +A  
Sbjct: 4   FDAYATHYE-DWYATPRGRLVWELEWRCLQKLLSLRPGE--KVLDAGCGTGVVSRALAAA 60

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV 125
           G +V   D+S  M+  A++     G   N+ ++      +    +   D ++    LE+V
Sbjct: 61  GAEVTGIDISPAMLAVAREK----GAGGNIVYLEGDMSSLP-FPDASFDAVVCFTALEFV 115

Query: 126 ADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYP 185
           A+P   L+ +W VL+PGG L +   N                      +K K   +  + 
Sbjct: 116 AEPERALEEMWRVLKPGGRLLVGVLNHRSSWARR--------------RKGKGVFAHAHF 161

Query: 186 RDPAQVYLWLEEAGWQIMGKTGVRVF 211
               ++   L +     +   GV  F
Sbjct: 162 YSVRELEQLLRKLNPCRVKWQGVIYF 187


>UniRef50_A8MFN6 Methyltransferase type 11 n=1 Tax=Alkaliphilus oremlandii OhILAs
           RepID=A8MFN6_ALKOO
          Length = 268

 Score =  153 bits (386), Expect = 8e-36,   Method: Composition-based stats.
 Identities = 51/270 (18%), Positives = 110/270 (40%), Gaps = 31/270 (11%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIK 61
            +  ++ +   +SR  Y +T               ++ +  P+   ++D G G G+ +++
Sbjct: 13  AENEWNRLNNSYSRVEYASTLY-------------LIEKYFPRTGNIIDIGSGPGRYSLE 59

Query: 62  MAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
           + +RG+ V L DLS   ++ AK+  E   +     +   +A ++    +   D +L    
Sbjct: 60  LLKRGYHVSLLDLSKNELEIAKKKIEESNLKAE-HYYCKSALELDFLEDEFFDGVLVMGP 118

Query: 122 LEWV---ADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMV--------AGNFD-YVQ 169
           L  +    +   VL+  + +L+ GGV  + + N  G L  ++           +F+ Y++
Sbjct: 119 LYHLHGAQEREKVLKDTYRILKKGGVALISYINTWGALKASVSEFPESFEDEAHFERYIK 178

Query: 170 AGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQ-----RDC 224
             +    + + +  +   P      +EE+G+ I+   G   F   L  + Q         
Sbjct: 179 GDLRFSSEESFTATFFTTPPLALKEVEESGFTIVSYAGAESFLSGLNIQLQNLHKYMPHV 238

Query: 225 YEALLELETRYCRQEPYITLGRYIHVTARK 254
           Y+  LE   +YC    Y     ++H+  +K
Sbjct: 239 YKNYLEAAPKYCELPQYRDATEHLHIIVQK 268


>UniRef50_B1BEI5 Probable S-adenosylmethionine-dependent methltransferase n=8
           Tax=Clostridium perfringens RepID=B1BEI5_CLOPE
          Length = 267

 Score =  152 bits (385), Expect = 9e-36,   Method: Composition-based stats.
 Identities = 58/238 (24%), Positives = 112/238 (47%), Gaps = 25/238 (10%)

Query: 37  VLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQ 96
           ++ E  PQ+ ++LD G G G+ +I++ +RG++V L DLS + ID AK   E+ G+  N  
Sbjct: 35  MIKEYFPQEGKILDIGSGPGRYSIELLKRGYEVSLMDLSEKSIDMAKNNIESMGLKAN-D 93

Query: 97  FIHCAAQDVASHLETPVDLILFHAVLEWV---ADPRSVLQTLWSVLRPGGVLSLMFYNAH 153
           +I   A  +    +   D IL    +  V    D   +L+    +L+PGG++ + + N+ 
Sbjct: 94  YICGDALYLDFIKDNTFDGILLMGPMYHVKSREDRIRILENCMRILKPGGIILIAYINSL 153

Query: 154 GLLM------------HNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQ 201
           G+L              N +   FD  + G  +++  + +  Y   P +    + E G+ 
Sbjct: 154 GVLKVGLSDFPQEYKDINKIYDLFD--EKGFSQEE--SFTETYFTVPEKAISEVNEVGFN 209

Query: 202 IMGKTGVRVFHD----YLREKH-QQRDCYEALLELETRYCRQEPYITLGRYIHVTARK 254
           I+ + G   F      Y+ + + + ++ Y  LL++ T  C  E +     ++ + A+K
Sbjct: 210 ILSRAGAESFLSGQAFYMTKYYLEDKEIYFNLLKVATEKCEDERFRDSTEHLIIVAKK 267


>UniRef50_A6WCY9 Methyltransferase type 12 n=2 Tax=Actinomycetales
           RepID=A6WCY9_KINRD
          Length = 265

 Score =  151 bits (381), Expect = 3e-35,   Method: Composition-based stats.
 Identities = 65/231 (28%), Positives = 106/231 (45%), Gaps = 9/231 (3%)

Query: 19  GTTKGQLRQ-AILWQDLDRVLAEMGPQ----KLRVLDAGGGEGQTAIKMAERGHQVILCD 73
              +G+ R   +LW+ + R+LA+        +L V+D GGG G  A+++A  GH+V++ D
Sbjct: 20  AKERGRPRTSTVLWEGVQRLLADAAAAPGAGELTVVDLGGGTGGLAVRVAALGHRVVVVD 79

Query: 74  LSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLE-TPVDLILFHAVLEWVADPRSVL 132
            S   +   ++     G+SD ++ +   A D+A+ LE    D++L H VLE V DPR+ L
Sbjct: 80  PSPDALAALERRTVEAGLSDRVRALQGDATDLAAVLEPGRADVLLCHGVLEVVDDPRAAL 139

Query: 133 QTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPR---DPA 189
           +     LRPGG LSL+       ++  +++G+ D     +     R    D  R   D A
Sbjct: 140 RAAHDALRPGGRLSLLVAQWPASVLARVLSGHLDQALHVLSDADHRWSGHDPLRRRFDRA 199

Query: 190 QVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP 240
                 + AG+ +    G R F D +     + D    LL          P
Sbjct: 200 SATALAQGAGFTVTAVEGTRTFSDVVPSTRTESDADVELLRRLEALASTSP 250


>UniRef50_D0RTX5 S-adenosylmethionine-dependent methyltransferase n=4
           Tax=Streptococcus RepID=D0RTX5_9STRE
          Length = 234

 Score =  150 bits (380), Expect = 3e-35,   Method: Composition-based stats.
 Identities = 58/249 (23%), Positives = 109/249 (43%), Gaps = 28/249 (11%)

Query: 14  SRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCD 73
            +N      G++   IL+  L  V      + ++VLD G G G  A  +AE+ +QV   +
Sbjct: 6   YKNHLEEPWGKIYYDILFDQLKNV------EGMKVLDFGSGFGIVANHLAEK-NQVTALE 58

Query: 74  LSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQ 133
            + +MI   K+       +++ + +  + + +    +   DLI+ H VLE++ D    L 
Sbjct: 59  PNMEMIIHRKR-------TNSYEQLQGSLEVLEIFKDESFDLIICHNVLEYIEDIDPYLM 111

Query: 134 TLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYL 193
               +L+ GG LS++ +N  G +MH ++  N       + K ++  L  DY        +
Sbjct: 112 AFSRLLKKGGKLSIVKHNYVGRIMHTVIFEN------DIKKARELLLGKDYLTHSMGQAV 165

Query: 194 WLEEAG------WQIMGKTGVRVFHDYLREKHQ-QRDCYEALLELETRYCRQEPYITLGR 246
           + E A       ++I+   G+R+F+       +      E +LE+E     Q PY  +  
Sbjct: 166 YYEIADVIKPYPFEILDFQGIRIFYGLQPNDVKTDPGWRENMLEMELSVNNQSPYRDIAA 225

Query: 247 YIH-VTARK 254
           + H    +K
Sbjct: 226 FQHYWLVKK 234


>UniRef50_A8MFN7 Methyltransferase type 11 n=1 Tax=Alkaliphilus oremlandii OhILAs
           RepID=A8MFN7_ALKOO
          Length = 266

 Score =  150 bits (378), Expect = 7e-35,   Method: Composition-based stats.
 Identities = 52/260 (20%), Positives = 107/260 (41%), Gaps = 17/260 (6%)

Query: 11  EKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVI 70
           EK+      TT     + I +     VL     +  R+L+ G G G  +    E+G+ VI
Sbjct: 9   EKYDEESRITTNNA--RKIEFLMTTGVLDNHIEKTHRILEIGAGTGAYSFYYGEKGNFVI 66

Query: 71  LCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVA---D 127
             D++ + I+   Q  + +G   N+Q     A D++       D++L    +  +    D
Sbjct: 67  ATDITPKHIEIIGQKMKERGNDINLQAEVANATDLSQFSSESFDVVLCLGPMYHLTNSSD 126

Query: 128 PRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAG------NF--DYVQAGMPKKKKRT 179
            ++ L     VL+ GG+L++ + N H +L   M+        NF    +  G+ ++ ++ 
Sbjct: 127 RKTCLSEALRVLKKGGLLAIAYINKHFVLNSVMIRNKEFLTRNFIDKILDTGVTREGEKE 186

Query: 180 LSPD--YPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKH--QQRDCYEALLELETRY 235
                 +   P ++  ++     +I+   GV     Y ++       + YE+ L    R 
Sbjct: 187 CFWTDAFFTTPDEMASYMNCFEVEIIDHLGVDGLSPYFKDAVDGMNSEEYESWLYYNMRS 246

Query: 236 CRQEPYITLGRYIHVTARKP 255
           CR++  + +  +  +  +K 
Sbjct: 247 CREKSILGISNHGLLLCKKK 266


>UniRef50_B0U3W1 3-demethylubiquinone-9 3-methyltransferase n=7 Tax=Xylella
           fastidiosa RepID=UBIG_XYLFM
          Length = 246

 Score =  149 bits (376), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 47/177 (26%), Positives = 77/177 (43%), Gaps = 6/177 (3%)

Query: 33  DLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVS 92
            LD +   +     RVLD G G G  +  +A +G  V   DL+ ++I  A+      G+ 
Sbjct: 44  RLDYISKRVSLSGARVLDVGCGGGLLSEALARQGAHVTAIDLAPELIKAARLHGLESGI- 102

Query: 93  DNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNA 152
             + +   A +D+ +    P D I    +LE V DP +++     +L+PGG L +   N 
Sbjct: 103 -QVDYRIQAIEDLLAEQPAPFDAIACMEMLEHVPDPAAIVDACAHLLKPGGRLFVSTINR 161

Query: 153 HGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVR 209
                   V G  +YV   +PK   +         PA++  WL  AG  +   +G+R
Sbjct: 162 TLAAFMLAVVGA-EYVVRLLPKGTHQY---KDFIRPAELAAWLRHAGLHLEDVSGMR 214


>UniRef50_C8SD34 Methyltransferase type 11 n=1 Tax=Ferroglobus placidus DSM 10642
           RepID=C8SD34_FERPL
          Length = 246

 Score =  147 bits (371), Expect = 4e-34,   Method: Composition-based stats.
 Identities = 48/213 (22%), Positives = 91/213 (42%), Gaps = 21/213 (9%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
           R +D     +    Y  + G      +W++   VLAE+   K+R+LD G G G  A+ +A
Sbjct: 10  RYWD-----YRSRDYDLSPGHSGLPEVWKE---VLAEIFEDKMRILDVGTGTGFLAVILA 61

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
           E GH+V+  D+S +M+  A++ A  KGV   + F    A+++    +   D  +   VL 
Sbjct: 62  ELGHEVVGIDISEEMLKVARRKAVDKGV--RIDFRVGDAENLP-FDDEEFDAAVCRHVLW 118

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAH----GLLMHNMVAGNFDYVQAGMP------ 173
            + +P   +     V++ GG + ++  N        L   +        +  +P      
Sbjct: 119 TLPNPERAISEWKRVVKKGGKVVIIDGNWEHGILATLKRLLGKAGMVIFEGKLPKNNSYS 178

Query: 174 KKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKT 206
           K+ K+ L         +V+  +++AG   +   
Sbjct: 179 KEVKKALPCYGSLTEEKVFELMKKAGLSRISIR 211


>UniRef50_A6WDP8 Methyltransferase type 12 n=1 Tax=Kineococcus radiotolerans
           SRS30216 RepID=A6WDP8_KINRD
          Length = 268

 Score =  146 bits (370), Expect = 4e-34,   Method: Composition-based stats.
 Identities = 72/254 (28%), Positives = 115/254 (45%), Gaps = 20/254 (7%)

Query: 19  GTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQM 78
            +  G+LR  ++ + L    AE+G + LRVLDAGGG+G+ A++ A  GH V + D S +M
Sbjct: 16  DSPWGRLRYRVVARVLREWCAELGGEPLRVLDAGGGDGRDAVQFALAGHAVTVLDRSPEM 75

Query: 79  IDRAKQAAEAKGVSDNMQFIHCAAQDVASHLE---------TPVDLILFHAVLEWVADPR 129
           +  A+ AA A GV D +  +    +D+ +               D++L H VL+      
Sbjct: 76  LALARAAAGAAGVGDRLHTVAADLEDLTALAALTRHREGGSGSFDVVLCHDVLQHRRSHE 135

Query: 130 SV---LQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPR 186
            V   + TL S +RPGG++SL+  +    ++  ++        A +    +R L P   R
Sbjct: 136 QVRADVATLTSSVRPGGLVSLLAPDPAADVVATVLREG--PAAAWIVLDAERALDPGTGR 193

Query: 187 -----DPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEA-LLELETRYCRQEP 240
                 P      L EAG  +  + G+      L E  +  D   A L ELE    R+E 
Sbjct: 194 SALRLSPEFAEDALTEAGCDVAQRAGILAVTTLLEEAERVDDRAAADLEELEVELSRREQ 253

Query: 241 YITLGRYIHVTARK 254
           +    RY  +  R+
Sbjct: 254 FRGTARYWLIGGRR 267


>UniRef50_A4FLY1 Methyltransferase n=1 Tax=Saccharopolyspora erythraea NRRL 2338
           RepID=A4FLY1_SACEN
          Length = 244

 Score =  146 bits (369), Expect = 7e-34,   Method: Composition-based stats.
 Identities = 56/235 (23%), Positives = 91/235 (38%), Gaps = 8/235 (3%)

Query: 27  QAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAA 86
             +L  +L +     G Q  RVLD GGG G  A+ +A  G  V + D S   +   ++ A
Sbjct: 7   HRVLEAELAQARKRRGGQPPRVLDVGGGSGVWAVPLASAGCAVTVVDPSPNALATLQRRA 66

Query: 87  EAKGVSDNMQFIHCAAQDVASH-LETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVL 145
              GV+D +  +      + +   E   DL+L H +LE V D  + L+ + +   PGG +
Sbjct: 67  ADAGVADRITPLQGDTDALHAISPEGGADLVLGHGLLEVVDDVAAALREMAAATAPGGAV 126

Query: 146 SLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL-----SPDYPRDPAQVYLWLEEAGW 200
           S++  N H  ++   + G              R       +     D   V   + EAG 
Sbjct: 127 SVLVANRHAAVLARALTGRVTEALKLFQDPDGRLHDCAADTLQRRFDSDSVERAMREAGM 186

Query: 201 QIMGKTGVRVFHDYLREKHQQ--RDCYEALLELETRYCRQEPYITLGRYIHVTAR 253
            +    G  V  D +     +      E+L ELE     + P   +   +H   R
Sbjct: 187 DVELIQGQGVLSDIVPGSVLESTTGAAESLAELERLAAARPPLRDIATRLHAIGR 241


>UniRef50_Q6MHC4 3-demethylubiquinone-9 3-methyltransferase n=1 Tax=Bdellovibrio
           bacteriovorus RepID=Q6MHC4_BDEBA
          Length = 284

 Score =  144 bits (363), Expect = 3e-33,   Method: Composition-based stats.
 Identities = 44/210 (20%), Positives = 86/210 (40%), Gaps = 10/210 (4%)

Query: 1   MQDRNFDDIAEKFSRNIYGT-TKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTA 59
           + +  +D +A+++           + +  +    +   +      K  +LD G G G  A
Sbjct: 40  VNNEAYDHLADRWYEAQDDPIALLRNQHKVEMPWILESIRRNIGYKAEILDMGCGAGFLA 99

Query: 60  IKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFH 119
             +A  GH+V   DLS   +  A    E++ ++ ++ +       V        D++   
Sbjct: 100 NDLAAAGHKVTGIDLSTSSLKVA----ESRDLTHSVHYRQGDVYQVP-FPNESFDVVAAM 154

Query: 120 AVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRT 179
            +LE V+DP+ V+     VLRPGG+     +N + L    ++ G   +V+         +
Sbjct: 155 DLLEHVSDPQRVIAEASRVLRPGGLFFFNTFNKNPLAWLVVIKGMEWFVKNTPNDYHVYS 214

Query: 180 LSPDYPRDPAQVYLWLEEAGWQIMGKTGVR 209
           L      +P ++ LWLE+         G+R
Sbjct: 215 L----FIEPKKLKLWLEDFSLDTQEIRGIR 240


>UniRef50_D1JEE5 Putative uncharacterized protein n=1 Tax=uncultured archaeon
           RepID=D1JEE5_9ARCH
          Length = 253

 Score =  143 bits (361), Expect = 5e-33,   Method: Composition-based stats.
 Identities = 43/213 (20%), Positives = 89/213 (41%), Gaps = 19/213 (8%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
            +D  ++ + RN+Y   K Q      W+ + +       + L +LD G G G  A+  AE
Sbjct: 15  YWDRRSQTYDRNVY---KSQNAAEHFWKSILKT-EIGTDRNLNILDVGTGTGFLALLFAE 70

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
            GH+V   D+S  M+++++  A  + ++  + F+H  A+++    +   D+++   +L  
Sbjct: 71  LGHKVTGIDISKSMLEKSRCNAYKQKLA--VNFMHGDAENLP-FDDGSFDIVMNRYLLWT 127

Query: 125 VADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKK-------- 176
           + DP++ +     V++ GG L L+    H   +H  +      +   + + +        
Sbjct: 128 LPDPKTAVNEWSRVVKSGGKLILIDGRWHDPAIHMRLRRFLASMIVLLTENRNPRMFASH 187

Query: 177 ----KRTLSPDYPRDPAQVYLWLEEAGWQIMGK 205
               K  L       P  V     E G + +  
Sbjct: 188 YATIKDQLPFFNGITPNDVVDLFTEVGLKKISV 220


>UniRef50_Q2FMN6 UbiE/COQ5 methyltransferase n=1 Tax=Methanospirillum hungatei JF-1
           RepID=Q2FMN6_METHJ
          Length = 253

 Score =  142 bits (359), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 48/215 (22%), Positives = 93/215 (43%), Gaps = 25/215 (11%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M    +D+ AE++        + +      W +L +      P  + VLD G G G+ ++
Sbjct: 11  MIQSAWDESAERYDMQHAHGVQSEEEHT-AWVNLFKQFTSDTP--ITVLDIGCGTGEMSL 67

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
            +AE GH V   DLS  M+ RA+  A  KG S  + F    A+ ++ + +   DL++   
Sbjct: 68  LLAEMGHSVHAIDLSENMLKRAEDKARKKGYS--ISFSIDDAESLS-YDDESFDLVINRH 124

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLM---------------FYNAHGLLMHNMVAGNF 165
           +L  + DP   L+    VL+P G+++++               F +  G+L    ++   
Sbjct: 125 LLWTLPDPEKALREWNRVLKPRGMIAVIDGLWFPESLSGKSRRFLSKLGIL----ISERR 180

Query: 166 DYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGW 200
           +  ++  P +    L      +  +   ++E AG+
Sbjct: 181 NPFKSYYPDELIDNLPHPKGMEAFEAVKYVERAGF 215


>UniRef50_Q0F561 3-demethylubiquinone-9 3-methyltransferase n=2 Tax=Proteobacteria
           RepID=Q0F561_9RHOB
          Length = 277

 Score =  140 bits (352), Expect = 6e-32,   Method: Composition-based stats.
 Identities = 51/209 (24%), Positives = 89/209 (42%), Gaps = 18/209 (8%)

Query: 8   DIAEKFSRNIYGTTKGQLRQAILWQ--DLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
            IAE F+               LW+  DL + L     Q L +LD G G G  +  +A  
Sbjct: 54  QIAEHFA---LDLPFEPAPNDNLWRLYDLGKPL-----QGLSILDVGCGGGLVSEPLARL 105

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV 125
           G +V   D SA  I  A Q A+       + ++H  A+D+ +  +   D+++   V+E V
Sbjct: 106 GAEVTGIDASAMSIQVATQHAQNTLTP--VTYVHTLAEDLVAQ-QQQFDVVINAEVVEHV 162

Query: 126 ADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYP 185
            D   ++     +++PGG+L L   N   +     + G  +YV   +P       S    
Sbjct: 163 QDQALLINQCAQLVKPGGMLILATLNRTVISYVFAIVGA-EYVMRYLPIGTH---SWSKF 218

Query: 186 RDPAQVYLWLEEAGWQIMGKTGVRVFHDY 214
             P ++  W +  G ++   TG++ F+ +
Sbjct: 219 VKPTELSAWAKSGGCELTSHTGMK-FNPW 246


>UniRef50_D1JD52 Putative uncharacterized protein n=1 Tax=uncultured archaeon
           RepID=D1JD52_9ARCH
          Length = 260

 Score =  139 bits (351), Expect = 7e-32,   Method: Composition-based stats.
 Identities = 37/141 (26%), Positives = 73/141 (51%), Gaps = 8/141 (5%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
             ++ + + F +     T+    Q   W+     L ++G + L++LD G G G  +I +A
Sbjct: 10  NYWNSMGKYFDKRPGDRTE---EQRNAWKQF--FLEKLGKKPLKILDVGTGTGFLSISLA 64

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
           E GH+V+  D+S  M+ +A++ AE +G+  N       A+ ++   +   D+++ +AVL 
Sbjct: 65  EIGHEVMGIDISEGMLSQARKKAEKRGL--NFDLRIEDAESLSLE-DETFDIVVSNAVLW 121

Query: 124 WVADPRSVLQTLWSVLRPGGV 144
            + +P   ++    VL+PGG 
Sbjct: 122 SLPNPEKAVREWKRVLKPGGT 142


>UniRef50_Q482G8 3-demethylubiquinone-9 3-methyltransferase n=27
           Tax=Gammaproteobacteria RepID=UBIG_COLP3
          Length = 246

 Score =  139 bits (351), Expect = 7e-32,   Method: Composition-based stats.
 Identities = 40/182 (21%), Positives = 80/182 (43%), Gaps = 8/182 (4%)

Query: 45  KLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQD 104
            ++++D G G G  +  +A+ G  V   D+  + ++ AK  A   GVS  + +    A++
Sbjct: 63  DMQIIDVGCGGGILSESLAKLGANVTGIDMGTEPLNVAKLHALETGVS--INYQKITAEE 120

Query: 105 VASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGN 164
            A       D++    +LE V DP SV+Q   ++++PGG++     N         +   
Sbjct: 121 KALENPGTFDVVTCMEMLEHVPDPASVIQACSTLVKPGGLIFFSTLNKSIKSYLLAILAA 180

Query: 165 FDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDC 224
            + +   +P         D    P+Q+  W EE G + +  +G+   ++ +   H+  D 
Sbjct: 181 -EKLLKIVPDGTH---DHDKFIRPSQLIGWAEEHGLKCIDASGIH--YNPITGNHKLNDS 234

Query: 225 YE 226
            +
Sbjct: 235 LD 236


>UniRef50_Q2FPU4 UbiE/COQ5 methyltransferase n=1 Tax=Methanospirillum hungatei JF-1
           RepID=Q2FPU4_METHJ
          Length = 250

 Score =  139 bits (351), Expect = 7e-32,   Method: Composition-based stats.
 Identities = 51/221 (23%), Positives = 93/221 (42%), Gaps = 23/221 (10%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
            ++  A +++  +    K +   A  W+ L      +G   L++LD G G G  +I +A 
Sbjct: 8   YWNSGAFRYNSGVERFLKSEKGTAG-WKSLFS--EYLGTAPLKILDVGTGPGSISIPLAS 64

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
            GH V   DLS  M+D A++ A A  V   + F    A+++    +   D ++   VL  
Sbjct: 65  MGHMVTAVDLSDNMLDLARKNAVASNV--IVDFRKGDAENLP-FDDNTFDAVVNRWVLWT 121

Query: 125 VADPRSVLQTLWSVLRPGGVLSLMFYNAHG----LLMHNMVAGNFDYVQAGMPKKKKRTL 180
           V DP S L+    V++PGG + ++  N +      +       +  Y+     +   + +
Sbjct: 122 VPDPTSALREWTRVVKPGGRVCIIDGNWYSGRKTFVQKVWKQASRLYISIRERRNAWKNI 181

Query: 181 SPDYPRD--------PAQVYLWLEEAGWQIMGKTGVRVFHD 213
            P+  +D        P    +  + AG      + V+VF D
Sbjct: 182 DPEVIQDLWSTHANRPEDDMVLFQNAGL-----SDVQVFMD 217


>UniRef50_D1JD55 Putative uncharacterized protein n=1 Tax=uncultured archaeon
           RepID=D1JD55_9ARCH
          Length = 263

 Score =  139 bits (351), Expect = 8e-32,   Method: Composition-based stats.
 Identities = 43/213 (20%), Positives = 90/213 (42%), Gaps = 18/213 (8%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
            +D     +       +K + ++A  W  L       G  +  VLD G G G  ++ +A+
Sbjct: 18  YWDGRGRFYDSVPGHGSKEKEKRA--W--LMEFKNVFGENRKNVLDVGTGTGFLSLLLAD 73

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
            GH+V   D+S  M+  AK+ A   G+   + F    A+++    +T  D ++   +L  
Sbjct: 74  FGHEVTGIDMSEGMLSVAKEKAHDMGL--KIHFERGDAENLPFDGQT-FDCVVCRHLLWT 130

Query: 125 VADPRSVLQTLWSVLRPGGVLSLM----------FYNAHGLLMHNMVAGNFDYVQAGM-P 173
           + +P   +     V + GG ++++          + +  G ++H M+    + V++   P
Sbjct: 131 LPNPEKAISEWIRVTKQGGKIAVIDGVWDRGIGRYLSRVGWILHVMITEKRNPVKSYHYP 190

Query: 174 KKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKT 206
           K+ +  L      D  ++  +L   G + +  T
Sbjct: 191 KEVRDKLPYVKGIDGEEIASFLSNFGLKEISVT 223


>UniRef50_C8XH01 Methyltransferase type 11 n=1 Tax=Nakamurella multipartita DSM
           44233 RepID=C8XH01_NAKMY
          Length = 262

 Score =  138 bits (349), Expect = 1e-31,   Method: Composition-based stats.
 Identities = 56/216 (25%), Positives = 96/216 (44%), Gaps = 6/216 (2%)

Query: 47  RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA 106
           RVLD GGG G  A+ +A  G  V + D S   +    + A+  GV+D +  +   A  + 
Sbjct: 44  RVLDVGGGSGTRAVPLAVLGCSVTVVDASVNSLAILHRRAQDAGVADRVVGVQADADRLE 103

Query: 107 S-HLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNF 165
           +      +DL+L H +LE V DP +V+  +   +RPGG +S++     G ++   +AG F
Sbjct: 104 AIAAPASIDLVLCHHLLEAVDDPAAVMGAVVRTVRPGGYVSILVAGRLGAVLGQTMAGRF 163

Query: 166 DYVQAGMPKKKKRTLSPDYPR---DPAQVYLWLEEAGWQIMGKTGVRVFHDYLRE--KHQ 220
           +  +  +     R+ + D  R   D   V   ++  G Q+   +GV V    +    +  
Sbjct: 164 EAARELLTGPDGRSGAADTLRRRFDVPGVRALVDSVGLQVESVSGVGVLVGLVSGVIRQA 223

Query: 221 QRDCYEALLELETRYCRQEPYITLGRYIHVTARKPQ 256
                  L  LE    +    + +   +HV AR+P 
Sbjct: 224 GPGGEADLAALEAAAGQHPELLHIAADLHVVARRPD 259


>UniRef50_A7MPA9 3-demethylubiquinone-9 3-methyltransferase n=6
           Tax=Gammaproteobacteria RepID=UBIG_ENTS8
          Length = 243

 Score =  138 bits (348), Expect = 2e-31,   Method: Composition-based stats.
 Identities = 47/211 (22%), Positives = 86/211 (40%), Gaps = 25/211 (11%)

Query: 45  KLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQD 104
             +VLD G G G  +  MA  G  V   D+ A+ +  A+  A   GV  N  ++    ++
Sbjct: 57  GKKVLDVGCGGGILSESMAREGANVTGLDMGAEPLAVARLHALESGVELN--YVQQTVEE 114

Query: 105 VASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGN 164
            A+      D++    +LE V DPRSV+Q    +++PGG +     N +       V G 
Sbjct: 115 HAAQHAGAYDVVTCMEMLEHVPDPRSVVQACAQLVKPGGHVFFSTLNRNAKSWLMAVVGA 174

Query: 165 FDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDC 224
            +YV   +PK             P+++  W++E   +   +  + + ++ L  +      
Sbjct: 175 -EYVLRMVPKGTH---DAKKFIRPSELLGWVDETPLE--ERHIIGLHYNPLTNRF----- 223

Query: 225 YEALLELETRYCRQEPYITLGRYIHVTARKP 255
                       +  P + +   +H  A+KP
Sbjct: 224 ------------KLAPGVDVNYMLHTQAKKP 242


>UniRef50_D1JD78 Putative uncharacterized protein n=1 Tax=uncultured archaeon
           RepID=D1JD78_9ARCH
          Length = 256

 Score =  138 bits (347), Expect = 2e-31,   Method: Composition-based stats.
 Identities = 47/217 (21%), Positives = 92/217 (42%), Gaps = 22/217 (10%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
           R++D  +  + +       G   + I W D+  + + +G ++  VLD G G G  AI +A
Sbjct: 17  RHWDGRSNDYGKF---RGYGSEEEKIAWMDV--LSSALGTERRNVLDVGTGPGDIAIYLA 71

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
           E  H V   D S +M+ RAK   +   +   ++F  C A+D+    +   D ++   +L 
Sbjct: 72  EMEHDVTGIDFSDEMLKRAKGRVKNSNL--QVKFDICDAEDL-YFEDESFDAVICRHLLW 128

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMF--------YNAHGLLMHNMVAGNFDYVQAGMPKK 175
            + +P   L+    V++PGG + ++          +    L+ ++V     Y Q   PK 
Sbjct: 129 TLPNPGKALREWTRVVKPGGKIVVIDGKWRSSSPIDRMRRLIRSLVF--LVYEQRKPPKS 186

Query: 176 KKRTLSPDYP----RDPAQVYLWLEEAGWQIMGKTGV 208
            K+ ++   P     +P +V     +     +    +
Sbjct: 187 YKKEINGKLPFRNGAEPEKVVELFNDLELVNVSAQDI 223


>UniRef50_Q8TJ84 UbiE/COQ5 methyltransferase n=1 Tax=Methanosarcina acetivorans
           RepID=Q8TJ84_METAC
          Length = 251

 Score =  138 bits (347), Expect = 2e-31,   Method: Composition-based stats.
 Identities = 59/258 (22%), Positives = 98/258 (37%), Gaps = 22/258 (8%)

Query: 4   RNFDDI-AEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
           R+F +  ++ F ++    T  +  +   W+ L   L        ++LD G G G  ++ +
Sbjct: 9   RDFWNYRSQTFDKSPGHYTASKEEEE-AWKGL---LRSKLDDAEKILDIGSGTGFLSLML 64

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
           A+ G++V+  DLS +MI RA   A+ +G+S  + F    A+ +        D I+  AVL
Sbjct: 65  ADMGYEVVGIDLSEEMIARASAKAKERGLS--IDFHQDDAEQLGFE-NNSFDAIVNRAVL 121

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSP 182
             +  P   ++    VLRPGG L    +         +       V        +R    
Sbjct: 122 WTLPHPDIAVREWMRVLRPGGKLCFFLHVPRNEREDALQ----KQVLNLWILLSERRNPW 177

Query: 183 DYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPYI 242
                  Q        G +        V  D L+         E + E+ET   R+ PY 
Sbjct: 178 RTLGSKGQAVNLPYNGGVKP------GVILDLLKSVGYSHVFAEPMHEIETLKSRRMPYP 231

Query: 243 TLGRYIH----VTARKPQ 256
               + H     TA KP+
Sbjct: 232 YRISHGHGQFCYTAEKPK 249


>UniRef50_D1JD67 Putative uncharacterized protein n=1 Tax=uncultured archaeon
           RepID=D1JD67_9ARCH
          Length = 252

 Score =  138 bits (347), Expect = 2e-31,   Method: Composition-based stats.
 Identities = 47/230 (20%), Positives = 97/230 (42%), Gaps = 16/230 (6%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
           ++ +   A+ +S+++  +     ++   WQ++   +   G +KL VLD G G    A  +
Sbjct: 6   NKYWSKDADNYSKSVRRSMHS-AKEKKGWQEIFTEV--FGKEKLNVLDVGTGPVIIAFLL 62

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
           AE GH V   DLS +M+  A++ A    +   ++F H  A+++    +   D ++   VL
Sbjct: 63  AELGHDVTGVDLSEEMLRNARENAAIFNIP--VEFRHGDAENLPFE-DESFDAVVNRHVL 119

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSL----MFYNAHGLLMHNMVAGNFDYVQAGMPKKKKR 178
             + +P   +     VL+ GG + +     F N     ++    G    +   + ++K  
Sbjct: 120 WTLPNPERAIAEWRRVLKTGGKIVIVDGNWFLNPEFRSLNRRARGVLAMLLVLITERKDL 179

Query: 179 TLSPDYPRDPAQV---YLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCY 225
             S  Y +   ++        +A  +I+       F D + ++   R  Y
Sbjct: 180 RKSGSYCKVEKKLWSTNKKRPDADIEILENLD---FKDIIVKEGINRRTY 226


>UniRef50_Q1QEI9 3-demethylubiquinone-9 3-methyltransferase n=59 Tax=Proteobacteria
           RepID=UBIG_PSYCK
          Length = 257

 Score =  136 bits (344), Expect = 5e-31,   Method: Composition-based stats.
 Identities = 43/170 (25%), Positives = 72/170 (42%), Gaps = 4/170 (2%)

Query: 39  AEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFI 98
           AEMG    +VLD G G G  +  MA RG  V   DL  + +  A   AE   + D +++ 
Sbjct: 64  AEMGLAGKKVLDVGCGGGILSESMARRGADVTGIDLGTENLKAASLHAEQSNLQDTLRYQ 123

Query: 99  HCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMH 158
           H   + +A+      D++    +LE V DP +++   + +L PGGV  L   N +     
Sbjct: 124 HIPVEALAATHAGQFDVVTCMEMLEHVPDPAAIVDACFKLLAPGGVCVLSTINRNPKSYL 183

Query: 159 NMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
             + G  +YV   + +             PA++     +A +      G+
Sbjct: 184 FAIVGA-EYVLRLLDRGTHDY---AKFITPAELDKMAIDAEFARQDIIGL 229


>UniRef50_Q3MEY9 Cyclopropane-fatty-acyl-phospholipid synthase n=5 Tax=Cyanobacteria
           RepID=Q3MEY9_ANAVT
          Length = 260

 Score =  136 bits (342), Expect = 9e-31,   Method: Composition-based stats.
 Identities = 46/201 (22%), Positives = 89/201 (44%), Gaps = 26/201 (12%)

Query: 14  SRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLR-VLDAGGGEGQTAIKMAERGHQVILC 72
           ++N +  T  Q + + +WQ  + +L  + PQ    +LD G G GQ   K+A+ G +V+  
Sbjct: 7   AKNFWDATLYQDKHSFVWQYGEDLLQLLNPQPGEFILDLGCGTGQLTEKIAQSGAEVLGT 66

Query: 73  DLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVL 132
           D +A MI++A+Q         ++ F    A++    ++ P+D +  +A+L WV +P + +
Sbjct: 67  DNAATMIEKARQN------YPHLHFDVADARN--FRVDKPLDAVFSNAMLHWVKEPEAAI 118

Query: 133 QTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKK-------RTLSPDYP 185
            ++   L+ GG     F             GN  Y+   +    +       + L+P Y 
Sbjct: 119 ASIHQALKSGGRFVAEFGGK----------GNIKYILEALYNALETLGIHNPQALNPWYF 168

Query: 186 RDPAQVYLWLEEAGWQIMGKT 206
               +    LE+ G+ +    
Sbjct: 169 PSIGEYVNILEKQGFDVTYAA 189


>UniRef50_C6PRH7 Methyltransferase type 11 n=1 Tax=Clostridium carboxidivorans P7
           RepID=C6PRH7_9CLOT
          Length = 252

 Score =  135 bits (341), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 32/144 (22%), Positives = 68/144 (47%), Gaps = 6/144 (4%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           ++  A+ + +      K +  + + W+    +   +G +  ++LD G G G  A+ +AE 
Sbjct: 12  WNIWAKGYDKQYSHGLKSE-EEKVQWKVF--LSEVIGKESKKILDVGTGTGFLALLLAEL 68

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV 125
           GH     D+S  M++ A++ A+   +  N+ F    A+++    +   D+++   +L  +
Sbjct: 69  GHNCTGLDISEGMMEVARKKAKEAKL--NINFGMGDAENLPCK-DNTYDIVVNRHLLWTI 125

Query: 126 ADPRSVLQTLWSVLRPGGVLSLMF 149
             P   L     VL+PGG L ++ 
Sbjct: 126 PHPEKALSEWIRVLKPGGKLVIID 149


>UniRef50_B1KQ47 Ubiquinone biosynthesis O-methyltransferase n=3 Tax=Shewanella
           RepID=B1KQ47_SHEWM
          Length = 270

 Score =  135 bits (341), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 50/225 (22%), Positives = 92/225 (40%), Gaps = 28/225 (12%)

Query: 6   FDDIAEKFSRN--------IYGTTKGQLRQAILWQDLDRVLAEMGP-QKLRVLDAGGGEG 56
           FD +AE++            +  T+    Q ++ +   R L +  P   L +LD G G G
Sbjct: 25  FDALAEEWRDPQGKFKHVLAFNLTRLTAIQMMIAEHFKRDLTQDIPFNDLTMLDIGCGVG 84

Query: 57  QTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLE------ 110
                ++++G  V   D S   ID A+Q AE   +  N+ + HC A+D+ +         
Sbjct: 85  LLCEPLSKQGAHVTGIDASCYNIDLARQHAEKNNI--NINYQHCLAEDLLAKQPINIANN 142

Query: 111 -------TPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAG 163
                     D++L   V+E V D +++++T   +++PGG+L +   N         + G
Sbjct: 143 QSDRIGSKHYDVVLNTEVIEHVEDQQALIKTCCELVKPGGILIMATLNRTIKSYVIGIIG 202

Query: 164 NFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
             +YV   +P          Y   P ++   +   G   +   G+
Sbjct: 203 A-EYVMRYLPIGTHDW---HYFVTPKEINTMISANGLTPITSQGM 243


>UniRef50_C0Q9K2 UbiG n=1 Tax=Desulfobacterium autotrophicum HRM2 RepID=C0Q9K2_DESAH
          Length = 232

 Score =  135 bits (341), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 49/201 (24%), Positives = 79/201 (39%), Gaps = 10/201 (4%)

Query: 11  EKFSRNIYGTTKGQLRQAILWQ----DLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERG 66
           EKF            R   L       L+ ++ +      RVLD G G G    K+A++ 
Sbjct: 11  EKFDDFATDWWDANGRMKSLHDINPLRLEYIMQQTDLTGKRVLDVGCGGGILTEKIAQQA 70

Query: 67  HQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVA 126
              I  D SA+M   A+  A+   +  ++ +I    + +    +T  D+IL   +LE V 
Sbjct: 71  GATIGIDASAEMTAIARTHAKQSNL--DILYIDTDIEHLTRFTQTGFDVILCMELLEHVP 128

Query: 127 DPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPR 186
              SV+      L PGG++     N + L+   +     +YV   +PK      S     
Sbjct: 129 SYASVIAACKKALNPGGIVIFATINRN-LMSFVLAVVCAEYVLGLLPKGTHDWAS---LI 184

Query: 187 DPAQVYLWLEEAGWQIMGKTG 207
            P ++     EAG +    TG
Sbjct: 185 KPEELKQACSEAGLKQKNITG 205


>UniRef50_Q8TJW5 Putative uncharacterized protein n=1 Tax=Methanosarcina acetivorans
           RepID=Q8TJW5_METAC
          Length = 306

 Score =  135 bits (339), Expect = 2e-30,   Method: Composition-based stats.
 Identities = 61/258 (23%), Positives = 108/258 (41%), Gaps = 18/258 (6%)

Query: 13  FSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILC 72
           +  N     +      I ++   R L    P+K R+LD GGG G+ +I +A +GH V L 
Sbjct: 46  YDGNPEYEWRRLEIHRIEYETTRRYLDIYLPKKSRILDVGGGPGRYSIYLASQGHNVTLF 105

Query: 73  DLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRS-- 130
           DLS++ I  AK  AE +GV     FIH  A ++  H +   D IL       + D     
Sbjct: 106 DLSSKNILLAKAKAEEQGVHLE-GFIHGNALELDHHTKGRFDAILCMGPSYHLTDESQRH 164

Query: 131 -VLQTLWSVLRPGGVLSLMFYNAHGLLM-------HNMVAGN---FDYVQAG--MPKKKK 177
            V+    +VL+PGG+L + F +A   ++       H ++       DY++ G  +  ++ 
Sbjct: 165 IVIDKCVNVLKPGGILFVSFISAFAPIIDMMKGYPHMILDEKDRLLDYLKDGTNIVSEEN 224

Query: 178 RTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREK--HQQRDCYEALLELETRY 235
              +  +  +PA +   +++   + +  T +         K      DC+ A +EL  + 
Sbjct: 225 PGFTDAWFENPANIEGIMKKYPLEKLVITAIEGMLSPNEGKINSLPEDCFNAFIELSMKL 284

Query: 236 CRQEPYITLGRYIHVTAR 253
                      ++    R
Sbjct: 285 STNPMTWGSCEHMLYIGR 302


>UniRef50_Q8TIA7 Phosphatidylethanolamine N-methyltransferase n=3 Tax=Methanosarcina
           RepID=Q8TIA7_METAC
          Length = 252

 Score =  134 bits (338), Expect = 3e-30,   Method: Composition-based stats.
 Identities = 41/147 (27%), Positives = 71/147 (48%), Gaps = 8/147 (5%)

Query: 9   IAEKFSRNIYGTTKGQ----LRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
           IA+ ++      T G+      + I+W+ +       G Q+L+VLD G G G  A+  AE
Sbjct: 7   IADYWNLRSSTYTNGENGFDAEERIIWRRMLENFLPPG-QRLKVLDVGTGPGFLALLFAE 65

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
            GH+V   D+S  M+++A+  A+  GV   +   H  A+ +    +   DL++   +L  
Sbjct: 66  MGHEVTAVDISMGMLEKARNNAKTLGV--KVDLFHGDAEKLPFE-DCYFDLVVNKYLLWT 122

Query: 125 VADPRSVLQTLWSVLRPGGVLSLMFYN 151
           +  P   +Q    VL+PGG +  +  N
Sbjct: 123 LPQPEIAVQEWMRVLKPGGRVFAIDGN 149


>UniRef50_A6UUC3 Methyltransferase type 11 n=1 Tax=Methanococcus aeolicus Nankai-3
           RepID=A6UUC3_META3
          Length = 210

 Score =  134 bits (337), Expect = 3e-30,   Method: Composition-based stats.
 Identities = 39/145 (26%), Positives = 72/145 (49%), Gaps = 9/145 (6%)

Query: 6   FDDIAEKFSR-NIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
           +D+ A+K+   + +G    + ++A+        L E+   + +VLD G G G  ++ +AE
Sbjct: 11  WDNHAKKYDNISAHGINSEKDKRAV-----RSALQEILGDRKKVLDVGCGTGFLSLILAE 65

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
            GH VI  DLS  M+ +AK+ AE  G   ++ F    A+++    +   D I+   +L  
Sbjct: 66  LGHDVIGVDLSEGMLSKAKKKAEENGY--DILFKLGDAENLPFDND-SFDAIVERHILWT 122

Query: 125 VADPRSVLQTLWSVLRPGGVLSLMF 149
           + +P   +     +L+ GG L L+ 
Sbjct: 123 LPNPEKAINGWTKLLKNGGKLILIE 147


>UniRef50_D2RYJ5 Methyltransferase type 11 n=3 Tax=Haloterrigena turkmenica DSM 5511
           RepID=D2RYJ5_9EURY
          Length = 226

 Score =  134 bits (337), Expect = 3e-30,   Method: Composition-based stats.
 Identities = 49/204 (24%), Positives = 92/204 (45%), Gaps = 20/204 (9%)

Query: 4   RNFDDIAEKFS-RNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
           + +DD +E +   + +     + R A  W  + R     G    R LD G G G  ++ +
Sbjct: 15  QYWDDRSESYDGDSQHAIHSDEQRDA--WLSILRDWTGDGDPPRRTLDVGCGTGVISLLL 72

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
           AE GH V   DLS  M++RA+  A  +  S  ++F +  A+ +++  E   DL+    ++
Sbjct: 73  AELGHVVTGVDLSTDMLERARAKARDRDRS--VEFRNGDAESISA-PENAYDLVTARHLV 129

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGM-PKKKKRTLS 181
             + +P + ++    V+RPGG + L             + G++D+ +A    ++    L 
Sbjct: 130 WTLPNPLAAIREWQRVVRPGGRIVL-------------IEGHWDFDEAFDGYQEIHDELP 176

Query: 182 PDYPRDPAQVYLWLEEAGWQIMGK 205
               R P ++   LEE G + +  
Sbjct: 177 LYDGRPPEELVDVLEEHGLERVEY 200


>UniRef50_UPI0001AF209D methyltransferase type 11 n=1 Tax=Streptomyces ghanaensis ATCC
           14672 RepID=UPI0001AF209D
          Length = 277

 Score =  133 bits (336), Expect = 4e-30,   Method: Composition-based stats.
 Identities = 66/251 (26%), Positives = 102/251 (40%), Gaps = 28/251 (11%)

Query: 19  GTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER-GHQVILCDLSAQ 77
            T   +  + +  + +D +    G    RVLDAG G G  A+ +AE  G  V    +S  
Sbjct: 41  DTPMAEASRRLTRKVVDALGVRAG---QRVLDAGCGPGGPALLVAEETGADVTGVTVSRF 97

Query: 78  MIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWS 137
                 Q A A+G+SD ++F H    ++  H +   D ++    L++  D    L  L+ 
Sbjct: 98  EAGAGTQKASARGLSDRVRFEHGDYAELGHHADGSFDAVMAMESLQYAPDLPRALAELFR 157

Query: 138 VLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEE 197
           VLRPGG L++  Y     L   +     D +       +K TL    P         L E
Sbjct: 158 VLRPGGALTMTDY----TLAARVPPAERDEL------AEKLTLPHLQP--VEGWLEVLRE 205

Query: 198 AGWQIMGKT--GVRVF---HDYLREKHQQRDCYEALLELETRYCRQEP---YITLG---- 245
           AG+++   T  G RVF     Y+    + RD   A    E     +E    + + G    
Sbjct: 206 AGFRVEEYTQCGPRVFGLGAKYVEAAEEGRDALRAAFGEEAVAGLKEAMADFFSPGAERI 265

Query: 246 RYIHVTARKPQ 256
            Y  VT R+P+
Sbjct: 266 EYSIVTVRRPR 276


>UniRef50_Q46ER7 UbiE/COQ5 methyltransferase n=4 Tax=Methanosarcina
           RepID=Q46ER7_METBF
          Length = 253

 Score =  133 bits (335), Expect = 6e-30,   Method: Composition-based stats.
 Identities = 48/222 (21%), Positives = 101/222 (45%), Gaps = 33/222 (14%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           +D+ +  +    +G     L +A  W+ + + +   G  KL VLD G G G+ ++  AE 
Sbjct: 16  WDESSATYDTQ-HGHKVKSLEEADAWKSMFKKIIPEG--KLDVLDVGCGTGELSVLFAEM 72

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV 125
           GH V   DLS +M+++ +  + ++G+S  ++F+   A++     E   D+++   +L  +
Sbjct: 73  GHNVTGLDLSEKMMEKGRLKSMSQGLS--IKFLKGDAEN-PPFDEKNFDVVITRHLLWTL 129

Query: 126 ADPRSVLQTLWSVLRPGGVLSLM---------------FYNAHGLLM---HNMVAGNF-D 166
            +P++ ++    VLR GG   ++               F ++ G+L+    N   GN+  
Sbjct: 130 PNPKTAVKNWNRVLRDGGYAIIVDGIWDDGSLNTRVRRFISSLGILIFEQANPWKGNYSK 189

Query: 167 YVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
            + A +P     +L         +   +L+ AG+  +    +
Sbjct: 190 ELAASLPNASGTSL--------EESRQYLKNAGFSKIDAYDI 223


>UniRef50_B6BTP2 3-demethylubiquinone-9 3-O-methyltransferase n=1 Tax=beta
           proteobacterium KB13 RepID=B6BTP2_9PROT
          Length = 237

 Score =  133 bits (335), Expect = 6e-30,   Method: Composition-based stats.
 Identities = 52/243 (21%), Positives = 95/243 (39%), Gaps = 15/243 (6%)

Query: 1   MQDRNFD---DIAEKFSRNIYGTTKGQLRQAILWQ----DLDRVLAEMGPQKLRVLDAGG 53
           M+ +NF+   +  EKF++  +           L       ++ +       +  +LD G 
Sbjct: 1   MEKQNFNVDLNEVEKFNKIAHKWWDPSSEFKPLHDINPLRVNYINDLFPLNEKNILDVGC 60

Query: 54  GEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPV 113
           G G  A  MA+ G  V   D S   I  AK  A+   +S + + +    +D         
Sbjct: 61  GGGILAESMAKLGGNVTGIDQSDIAIKIAKLHAKENNLSIDYKLL--NIEDFLKKDSNKF 118

Query: 114 DLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMP 173
           D+I    ++E V DP S++++    L+  G L +   N +       + G  +Y+   +P
Sbjct: 119 DVITCLEMIEHVPDPASIIKSCSKKLKKNGRLYVSTINRNLKAFLFAIVGA-EYILNLLP 177

Query: 174 KKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELET 233
           K        D    P++V  W       I   TG+  ++ +L++     D     + LE 
Sbjct: 178 KGTHHY---DKFIKPSEVKSWANSLNMNISNITGM-TYNPFLKKYSLGSDVSVNYI-LEL 232

Query: 234 RYC 236
           R+ 
Sbjct: 233 RFN 235


>UniRef50_B1I4Q7 Methyltransferase type 11 n=1 Tax=Candidatus Desulforudis
           audaxviator MP104C RepID=B1I4Q7_DESAP
          Length = 265

 Score =  133 bits (335), Expect = 6e-30,   Method: Composition-based stats.
 Identities = 43/192 (22%), Positives = 80/192 (41%), Gaps = 16/192 (8%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           FD +AE +    Y T  G+ +   L   L   LA   P + R LD G G G+ ++ +AE+
Sbjct: 4   FDRVAEDYD-AWYETPLGR-KVDQLEMCLFMRLAAPKPGE-RALDGGCGTGRLSLALAEK 60

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV 125
           G  V   DLS +M++ A+    +     N+  +    +++        DL+    VLE+ 
Sbjct: 61  GLVVTGVDLSPRMLEVARNRTRSH---ANITLMQADVENLP-FPSLSFDLVTAFTVLEFT 116

Query: 126 ADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYP 185
            +P + ++ LW +++PGG L +   N+            + + +       +   +    
Sbjct: 117 GNPEAAVRELWRLVKPGGRLVVGVLNSWSP---------WAWQRRRRAGTGESVFAHAQF 167

Query: 186 RDPAQVYLWLEE 197
             P  +   L  
Sbjct: 168 FSPWSMKAVLTA 179


>UniRef50_Q21UL3 3-demethylubiquinone-9 3-methyltransferase n=5 Tax=Proteobacteria
           RepID=UBIG_RHOFD
          Length = 252

 Score =  133 bits (334), Expect = 7e-30,   Method: Composition-based stats.
 Identities = 44/206 (21%), Positives = 85/206 (41%), Gaps = 12/206 (5%)

Query: 6   FDDIAEKFSRNIYGTTKGQLR--QAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
           F D+A ++        +G+ R    I    L+ +         +VLD G G G  A  MA
Sbjct: 27  FSDLAHRWWD-----LEGEFRPLHQINPLRLEWINHLCPVAGQQVLDVGCGGGILADSMA 81

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
             G QV   DL+++ +  A+  A     + N+Q+   + + +A+      D++    +LE
Sbjct: 82  RLGAQVTGIDLASKALRVAQLHALEAQ-TPNLQYQEISVEALAAQQPGSFDVVTCMEMLE 140

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPD 183
            V DP SV++   ++++PGG +     N         + G  +YV   +P+         
Sbjct: 141 HVPDPASVVRACATLVKPGGWVFFSTLNRSPKSFVLAIVGA-EYVLNLLPRGTHEYAKMI 199

Query: 184 YPRDPAQVYLWLEEAGWQIMGKTGVR 209
               P+++  +       +    G++
Sbjct: 200 R---PSELASYCRSVELDLRHTRGMQ 222


>UniRef50_Q65VD6 SmtA protein n=2 Tax=Gammaproteobacteria RepID=Q65VD6_MANSM
          Length = 256

 Score =  133 bits (334), Expect = 7e-30,   Method: Composition-based stats.
 Identities = 47/168 (27%), Positives = 78/168 (46%), Gaps = 8/168 (4%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGP-QKLRVLDAGGGEGQTAIKM 62
           R +++ AE +SR  +   + Q  + + WQ L  +LA     Q L+VLD G G G  AI M
Sbjct: 16  RYWNNRAEGYSR--HNQQELQSIKRLKWQQL--LLAHAPKKQNLKVLDIGTGPGFFAIIM 71

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
           A+ G QV   D ++ M+++AK  A    V  +++F+      +    +   DLI+   V 
Sbjct: 72  AQAGAQVTAIDATSNMLEQAKYNAAQAMV--DIRFVRGDVHHLP-FADESFDLIISRNVT 128

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQA 170
             +++P    +    VL+ GG L     N +  L        F+  +A
Sbjct: 129 WNLSEPEQAYKEWHRVLKCGGNLLNFDANWYLFLYDEQRRRAFEQDRA 176


>UniRef50_Q47QY4 Putative methyltransferase n=1 Tax=Thermobifida fusca YX
           RepID=Q47QY4_THEFY
          Length = 252

 Score =  132 bits (333), Expect = 1e-29,   Method: Composition-based stats.
 Identities = 65/251 (25%), Positives = 112/251 (44%), Gaps = 10/251 (3%)

Query: 14  SRNIYGTTKGQLRQAILWQDLDRVLAEMGP---QKLRVLDAGGGEGQTAIKMAERGHQVI 70
           S+   G      R A++W+ L   LA +     + L ++DAGGG G  A+ +A  GH+V 
Sbjct: 4   SKVSSGRASSAARTAVVWEALTAELARLAEEFVEPLNIVDAGGGTGGAAVPLARLGHRVT 63

Query: 71  LCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVAS-HLETPVDLILFHAVLEWVADPR 129
           + D S   +   ++ A   GV   +  +   A+ +     E    L+L H V+E V DP 
Sbjct: 64  VVDSSPDSLAALERRAAEAGV--RVNAVQGDAEGLRELLPEASAHLVLVHNVVEHVDDPL 121

Query: 130 SVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPD---YPR 186
           + L+ + S+ +P G +S++  NA   ++H  +AG+     A +   + R    D      
Sbjct: 122 TALRDVVSITQPRGAVSVLATNAVAAVLHRALAGHLADALALLQSNEGRWGPSDPMPRRY 181

Query: 187 DPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKH-QQRDCYEALLELETRYCRQEPYITLG 245
              Q+   + EAG ++    GVR+  D L  +  +     + LL +E           + 
Sbjct: 182 TAEQLTALVREAGLEVHELRGVRILGDLLPGRVFEDPQTPDTLLAVEKAASAHAELSRIA 241

Query: 246 RYIHVTARKPQ 256
             +HV AR+P 
Sbjct: 242 TQLHVMARRPA 252


>UniRef50_Q5WCE8 S-adenosylmethionine (SAM)-dependent methyltransferase n=3
           Tax=Bacillus RepID=Q5WCE8_BACSK
          Length = 261

 Score =  132 bits (333), Expect = 1e-29,   Method: Composition-based stats.
 Identities = 57/267 (21%), Positives = 103/267 (38%), Gaps = 39/267 (14%)

Query: 1   MQDRN-FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLR-VLDAGGGEGQT 58
           M  R+ F+D    ++ N+Y       R A + +  + +L  + P K   +LD G G G  
Sbjct: 1   MNKRSPFND---HWNSNLYDN-----RHAFVSKFGNHLLELLQPTKKEAILDLGSGTGDL 52

Query: 59  AIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILF 118
           A ++A+ G  V   D S+ M+ +A+          ++ F    A ++        D +L 
Sbjct: 53  ANELAKLGAVVTGVDQSSNMVAKARSK------YPHLLFDMADATNLPFT--ETFDAVLS 104

Query: 119 HAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKR 178
           +AVL WV D  + L+++W  L+PGG   +  +   G +            QAG P   K+
Sbjct: 105 NAVLHWVLDAEAALKSIWRALKPGGRF-VAEFGGKGNVETITTELVAQIKQAGCPYSSKQ 163

Query: 179 TLSPDYPRDPAQVYLWLEEAGWQI---------MGKTGVRVFHDYLR-------EKHQQR 222
              P Y     +    +E+ G+ +             G   F ++L         +  ++
Sbjct: 164 F--PWYFPSIGEYTSLMEKTGFSVSFARLYERPTPLEGADGFRNWLEMFANPFFNEIDEQ 221

Query: 223 DCYEALLELETRYC--RQEPYITLGRY 247
           D    + + E        E    +  Y
Sbjct: 222 DKQAIIAKTEIALQPVLMEEGQWIADY 248


>UniRef50_C9L9K2 SmtA protein n=6 Tax=Bacteria RepID=C9L9K2_RUMHA
          Length = 564

 Score =  132 bits (332), Expect = 1e-29,   Method: Composition-based stats.
 Identities = 39/134 (29%), Positives = 66/134 (49%), Gaps = 4/134 (2%)

Query: 22  KGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDR 81
           + +L   I  + L  +L  +  +KL++LD G G G   I MA++GH+VI  DL+A MI R
Sbjct: 347 RAELHDDIAQRWLKEILQYVPKKKLKILDVGCGSGFFTILMAQQGHEVIGVDLTADMITR 406

Query: 82  AKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRP 141
           AK+ A  +    +  F    A+++    +   D+++   +   + D          VL+ 
Sbjct: 407 AKELAAEE--KADCTFQVMDAENL-EFADEAFDMVISRNLTWTLPDAERAYSEWLRVLKK 463

Query: 142 GGVLSLMFYNAHGL 155
           GG L L F   +G+
Sbjct: 464 GGCL-LNFDANYGI 476


>UniRef50_B8GRY2 Ubiquinone biosynthesis O-methyltransferase n=1
           Tax=Thioalkalivibrio sp. HL-EbGR7 RepID=B8GRY2_THISH
          Length = 251

 Score =  132 bits (332), Expect = 1e-29,   Method: Composition-based stats.
 Identities = 48/211 (22%), Positives = 93/211 (44%), Gaps = 8/211 (3%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGP-QKLRVLDAGGGEGQTA 59
           + ++ +D     +  +     +    +  L + LDR  A   P + L+VLD G G G  +
Sbjct: 24  LAEKWWDTTGPFWPLHTLNRLRVAYIRDRLCERLDRDPASARPLEGLKVLDIGCGGGILS 83

Query: 60  IKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFH 119
             MA  G  V   D++ + I  A   A+ + +   +++   +A+++A   E   DL+L  
Sbjct: 84  ESMARLGADVHGIDVTPRNIAVASLHAQGQDLP--LRYETVSAEELAERGE-QYDLVLNM 140

Query: 120 AVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRT 179
            V+E VAD    +     ++RPGG   +   N + +     + G  +Y+   +P+   + 
Sbjct: 141 EVVEHVADLPGFMAACNRLVRPGGYGFIATINRNPVSFLVAILGA-EYLLRWLPRGTHQW 199

Query: 180 LSPDYPRDPAQVYLWLEEAGWQIMGKTGVRV 210
                   P ++   L   G +++ + GVRV
Sbjct: 200 ---RRFPKPGELESLLAADGLEVIERIGVRV 227


>UniRef50_B3S9Y1 Putative uncharacterized protein n=1 Tax=Trichoplax adhaerens
           RepID=B3S9Y1_TRIAD
          Length = 302

 Score =  132 bits (332), Expect = 1e-29,   Method: Composition-based stats.
 Identities = 46/227 (20%), Positives = 89/227 (39%), Gaps = 18/227 (7%)

Query: 4   RNFDDIAEKF----SRNIYGTTKGQLRQAILWQDL------DRVLAEMGPQKLRVLDAGG 53
           + F DIA K+    ++N+       +R  ++   L       ++         ++LD G 
Sbjct: 55  KQFSDIASKWWQWNNKNMPLHALNMVRVPLIRDALLGDEKSHKIDQPRPLSGYKILDVGC 114

Query: 54  GEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKG-VSDNMQFIHCAAQDV-ASHLET 111
           G G     +A  G QV   D S+++I+ AK  A     V+ N+ +     + +  +    
Sbjct: 115 GGGILCEPLARLGAQVTGIDASSEIINVAKAHASKCDRVAANVSYQCTTIEQLTTTENAQ 174

Query: 112 PVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAG 171
             D ++   V+E V +    + +   +++PGG   +   N   L    M+ G  +Y+   
Sbjct: 175 SFDAVIASEVIEHVDNVDLFVSSCCQLIKPGGKHIVTTINRTPLSYAVMIIGG-EYISRI 233

Query: 172 MPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREK 218
           +P              P ++   LEE G  +    G+  F++ L   
Sbjct: 234 IPAGSHDW---KKFITPKELTKKLEEGGLNVDFIGGI--FYNPLTNN 275


>UniRef50_B6YVU2 UbiE/COQ5 methyltransferase n=4 Tax=Thermococcus RepID=B6YVU2_THEON
          Length = 223

 Score =  132 bits (332), Expect = 1e-29,   Method: Composition-based stats.
 Identities = 45/211 (21%), Positives = 81/211 (38%), Gaps = 23/211 (10%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M +  F+ IA ++  + Y T  GQ         +  +L     +  + LD G G G   +
Sbjct: 1   MAE-YFNRIAGRYD-DWYRTKTGQYVDRTEKWLVFSMLQT---KSGKALDLGCGTGNYTL 55

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
           ++  RG  VI  D S  M++ A            +  I   A  +    +   DL+L   
Sbjct: 56  ELKRRGFDVIGLDASEGMLEIAMAK--------GLNCIKGDAYSLP-FPDESFDLVLSVT 106

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
           + E++ +P  V+  +  VL+PGG + +   N             F  +++   +   R  
Sbjct: 107 MFEFIHEPEKVIAEIHRVLKPGGEVLIGTMNGRSPWFF------FKRLKSLFVETAYRY- 159

Query: 181 SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVF 211
                  P ++ L L+  G+  +   GV  F
Sbjct: 160 --ARFYTPRELELLLKNGGFTEVESAGVIFF 188


>UniRef50_C5A2C6 SAM-dependent methyltransferase, ubiE/COQ5 family n=7
           Tax=Thermococcaceae RepID=C5A2C6_THEGJ
          Length = 228

 Score =  131 bits (331), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 52/227 (22%), Positives = 97/227 (42%), Gaps = 16/227 (7%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
            F++    F +        + R+ I  ++L+ +L +   +K +VLD G G G  +  + +
Sbjct: 2   TFEEYYSAF-KAYSDIYSDEYRKRI--ENLEPLLMKFMKEKGKVLDLGCGAGGFSFLLED 58

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
            G  V+  D S  M+  A+  A+ KG    ++FI   A+++    +   D +LF   L  
Sbjct: 59  LGFTVVGVDNSEYMLSLARGFAKEKG--SKVEFIKADARELPFE-DNTFDYVLFIDNLVH 115

Query: 125 VA--DPRSVLQTLWSVLRPGGVLSLMFYNAHGL---LMHNMVAGNFDYVQAGMPKKKKRT 179
               D     + +  VL+PGG L L F +   L   LM+  V G   ++   +P K ++T
Sbjct: 116 FEPLDLGKAFREMARVLKPGGKLILQFTDLRALLPVLMNGQVIGAEYWISKVLPDKDEKT 175

Query: 180 LSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYE 226
           +  ++  +            + + GKT V +      +K  +    E
Sbjct: 176 VLIEFQSEEKSFR-----VRFNVWGKTAVELLAKLYFQKVGEEKINE 217


>UniRef50_A0Y980 3-demethylubiquinone-9 3-methyltransferase n=1 Tax=marine gamma
           proteobacterium HTCC2143 RepID=A0Y980_9GAMM
          Length = 241

 Score =  131 bits (330), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 41/184 (22%), Positives = 83/184 (45%), Gaps = 8/184 (4%)

Query: 25  LRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQ 84
           +R   + + + +    +  + LR+LD G G G  A +MA++G  V   D++A+ I  A+Q
Sbjct: 40  MRAPFVTEKIQQHFKTVSLKGLRILDIGCGAGLLAERMAKQGATVTGIDVAAKNIGIARQ 99

Query: 85  AAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGV 144
            A+ +G+   + +   A + +    +   D++L   V+E V+D    +     +   GG+
Sbjct: 100 HAQTQGLV--IDYRCGAVEALKDVGD--FDVVLNMEVIEHVSDLPLFMSRTCDLTGAGGL 155

Query: 145 LSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMG 204
           + L   N         + G  +Y+   +P+      +      P +  L L+  G  ++ 
Sbjct: 156 MFLATINRTWFSWLTTIVGA-EYILGWLPRGTH---TWQRYVTPEEAVLSLQRGGLSVLS 211

Query: 205 KTGV 208
           +TGV
Sbjct: 212 RTGV 215


>UniRef50_B8H209 3-demethylubiquinone-9 3-methyltransferase n=13
           Tax=Alphaproteobacteria RepID=UBIG_CAUCN
          Length = 252

 Score =  131 bits (329), Expect = 3e-29,   Method: Composition-based stats.
 Identities = 45/184 (24%), Positives = 76/184 (41%), Gaps = 6/184 (3%)

Query: 25  LRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQ 84
           +R+  L +      A    + L +LD G G G  +  MA  G  V   D S + I  A  
Sbjct: 49  IREQALARFDRDGAARAPFEGLTLLDIGCGGGLLSEPMARLGFAVTAIDASEKNIKTAAT 108

Query: 85  AAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGV 144
            A  +G+  ++ +    A+ + +    P D++L   V+E VADP   L+T   +L+PGG+
Sbjct: 109 HAAEQGL--DIGYRPATAEQLLAEGAGPFDVVLTMEVIEHVADPGEFLRTCAKLLKPGGI 166

Query: 145 LSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMG 204
           + +   N     +     G  +YV   +P              P ++  +L      + G
Sbjct: 167 MFVATLNRTLKALALAKIGA-EYVLRWVPPGTHDW---KQFLKPEELRAFLAGEPVAMQG 222

Query: 205 KTGV 208
             GV
Sbjct: 223 PFGV 226


>UniRef50_B7MFZ8 3-demethylubiquinone-9 3-methyltransferase n=131 Tax=Proteobacteria
           RepID=UBIG_ECO45
          Length = 240

 Score =  131 bits (329), Expect = 3e-29,   Method: Composition-based stats.
 Identities = 40/164 (24%), Positives = 72/164 (43%), Gaps = 6/164 (3%)

Query: 45  KLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQD 104
             +VLD G G G  A  MA  G  V   D+  + +  AK  A   G+   + ++    ++
Sbjct: 57  GKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGI--QVDYVQETVEE 114

Query: 105 VASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGN 164
            A+      D++    +LE V DP+SV++    +++PGG +     N +G      V G 
Sbjct: 115 HAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTLNRNGKSWLMAVVGA 174

Query: 165 FDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
            +Y+   +PK             PA++  W+++   +    TG+
Sbjct: 175 -EYILRMVPKGTHDV---KKFIKPAELLGWVDQTSLKERHMTGL 214


>UniRef50_B8HNX7 Ubiquinone biosynthesis O-methyltransferase n=1 Tax=Cyanothece sp.
           PCC 7425 RepID=B8HNX7_CYAP4
          Length = 258

 Score =  130 bits (328), Expect = 3e-29,   Method: Composition-based stats.
 Identities = 37/167 (22%), Positives = 67/167 (40%), Gaps = 7/167 (4%)

Query: 44  QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQ 103
           Q  RVLD G G G     MA  G +V   D S   I  A++ A+   +   + +    A+
Sbjct: 45  QNCRVLDVGCGGGLACEFMARLGARVSGMDRSKNSIQIAQEHAKQSEL--QINYQQGNAE 102

Query: 104 DVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAG 163
           D+  + +   D ++   VLE V +   V+  ++ VL+PGG+      N        ++  
Sbjct: 103 DLP-YQQNSFDCVVCFDVLEHVYNRNRVISEIYRVLKPGGIFFFDTINRT-FQSKLVMIW 160

Query: 164 NFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRV 210
             + +   +P+             P ++   L + G+  +   G  V
Sbjct: 161 LLENILRQLPQGLHDW---HNFIQPHELEKILRDLGFIQIELKGFDV 204


>UniRef50_C8WEG5 Ubiquinone biosynthesis O-methyltransferase n=3 Tax=Zymomonas
           mobilis RepID=C8WEG5_ZYMMN
          Length = 263

 Score =  130 bits (326), Expect = 6e-29,   Method: Composition-based stats.
 Identities = 47/189 (24%), Positives = 76/189 (40%), Gaps = 15/189 (7%)

Query: 25  LRQAILWQDLDRVLAEMGPQKL-----RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMI 79
           +R + + Q +D+                VLD G G G  +  +   G  V   D + + I
Sbjct: 59  VRLSYIRQAIDQYFVSAFGNPFPLMGKSVLDIGCGAGLLSEPLCRLGGDVTGVDAAFENI 118

Query: 80  DRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVL 139
             AK  AE + +  N++++     ++ S  +T  DLI    VLE VA+P   +Q +   L
Sbjct: 119 AVAKAHAEEQHL--NIRYLTG---ELESVEDTNFDLITAMEVLEHVAEPEQFIQAIADKL 173

Query: 140 RPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAG 199
            P G+L L   N    L+  M+         G+P K            P +    LE+AG
Sbjct: 174 DPNGLLILSTPNR--TLLSKMMIIGIGETLGGIPAKTHDW---SRFLKPEETQKLLEKAG 228

Query: 200 WQIMGKTGV 208
             +    G+
Sbjct: 229 LVVTDIIGM 237


>UniRef50_Q28VP7 3-demethylubiquinone-9 3-methyltransferase n=37 Tax=Proteobacteria
           RepID=UBIG_JANSC
          Length = 254

 Score =  130 bits (326), Expect = 6e-29,   Method: Composition-based stats.
 Identities = 51/212 (24%), Positives = 88/212 (41%), Gaps = 10/212 (4%)

Query: 6   FDDIAEKFS-RNIYGTTKGQLRQAILWQDLDRVLAEMGP-QKLRVLDAGGGEGQTAIKMA 63
           + D+  KF   ++   T+       +  +  R L    P   L +LD G G G  A  MA
Sbjct: 29  WWDLEGKFKPLHMLNPTRLDYITQQIAAEFGRDLKADAPFAGLHILDIGCGGGLLAEPMA 88

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
             G  V+  D + + I  A+  A   G+   + + H  A+ +A   E   D++L   V+E
Sbjct: 89  RLGADVVGADAAERNIPVAQVHAAQSGLE--IDYRHTTAEAMADAGE-QFDVVLNMEVVE 145

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPD 183
            V DP   L     +L+PGG++     N +       + G  ++V   +PK         
Sbjct: 146 HVVDPLGYLTACQRLLKPGGLMVCSTLNRNPKSYLMAIIGA-EHVMRWLPKGTHEW---S 201

Query: 184 YPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYL 215
               P +++  + +AG   + + G  VF+  L
Sbjct: 202 KFITPDELFDLIRQAGLDPVDRKGF-VFNPLL 232


>UniRef50_B5JEA6 Methyltransferase domain family n=1 Tax=Verrucomicrobiae bacterium
           DG1235 RepID=B5JEA6_9BACT
          Length = 269

 Score =  129 bits (325), Expect = 8e-29,   Method: Composition-based stats.
 Identities = 56/262 (21%), Positives = 101/262 (38%), Gaps = 29/262 (11%)

Query: 11  EKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLR-VLDAGGGEGQTAIKMAERGHQV 69
           E +SR   G  +G    A++ + +D +LAE   +     LD G G G TA   +E G + 
Sbjct: 16  ETWSRCASGYIEG--FGALVAEAIDSILAEASVKNGTFCLDVGTGPGNTAKSASELGART 73

Query: 70  ILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPR 129
           I  D S  M+  A+        +  ++F++ +A+ +    +   D ++ + +L    +P 
Sbjct: 74  IGIDFSDTMLAEARVR------NPELEFLNASAEKLP-FADDEFDAVVGNYILHHSGEPE 126

Query: 130 SVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPA 189
            +L   + VL+PGG  +   ++    L    +         G P      L      D  
Sbjct: 127 KILSDSFRVLKPGGKAAFTVWSKPEKLEAFGLFFGAVGEHLGSPDLPHGPL--FGISDFD 184

Query: 190 QVYLWLEEAGWQIMGKTG-------------VRVFHDY----LREKHQQRDCYEALLELE 232
             +  L EAG+                    +R FHD+    + +K  +    E +L+  
Sbjct: 185 HFHHLLREAGFTKTSVRELPTVWKTPSISSYLRAFHDWANLNVVDKEIREKIEETILKSS 244

Query: 233 TRYCRQEPYITLGRYIHVTARK 254
            RY  +  Y      I ++  K
Sbjct: 245 GRYQSEGVYYIPNPSILLSGTK 266


>UniRef50_Q465A0 Putative uncharacterized protein n=2 Tax=Methanosarcina
           RepID=Q465A0_METBF
          Length = 244

 Score =  129 bits (325), Expect = 8e-29,   Method: Composition-based stats.
 Identities = 52/253 (20%), Positives = 104/253 (41%), Gaps = 27/253 (10%)

Query: 1   MQDR---NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQ 57
           M+D+    +D  +  +        K    +  +W+ +   +  +  +K+R ++ G G G 
Sbjct: 7   MKDKILEYWDYRSSDYHTE---YAKCMDEEMEIWKSVFSEIL-LTDKKIRAVEVGTGPGL 62

Query: 58  TAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLIL 117
            AI +A  GH V   DLS  M+++A + A+ KGV  ++  +   A+ +    +   D +L
Sbjct: 63  LAISLAAMGHDVTGVDLSENMLEKAAENAKEKGV--DVSLVQGDAEKIP-LNDGEYDFVL 119

Query: 118 FHAVLEWVADPRSVLQTLWSVLRPGGVL----SLMFYNAHGLLMHNMVAGNFDYVQAGMP 173
              +L  +  P   +     +L+ GG++     L F N  G    +     F+ + +G+ 
Sbjct: 120 SKYLLWTLPQPDKFMSECCRLLKDGGLMMIVDGLWFQNPDGTEKKSSRYEKFNELYSGV- 178

Query: 174 KKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELET 233
              K  L       P ++    +  G++ +     R   DY  +   +R+        E 
Sbjct: 179 ---KPNLPLAKNNTPERITALAQSHGFEAVSW---RFLKDY--DAFLERNDPS---GHEA 227

Query: 234 RYCRQEPYITLGR 246
            Y  Q P++ L +
Sbjct: 228 GY-IQPPHMVLAK 239


>UniRef50_Q2FPT3 UbiE/COQ5 methyltransferase n=1 Tax=Methanospirillum hungatei JF-1
           RepID=Q2FPT3_METHJ
          Length = 252

 Score =  129 bits (325), Expect = 8e-29,   Method: Composition-based stats.
 Identities = 38/142 (26%), Positives = 72/142 (50%), Gaps = 7/142 (4%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
            +++ ++ F +++         +  LW++  R +  +G  K  VLD G G G  AI +AE
Sbjct: 18  YWNERSKTFDQDV--GHGADHHECQLWKNQLRTI--IGDDKKDVLDFGTGTGMIAINLAE 73

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
            GH V   DL  +M+D A + AE+K +S  ++F+   A++     +   D+++   +L  
Sbjct: 74  LGHSVTGIDLCEEMLDIANRKAESKDLS--IRFLLGDAEN-PEFPDRMFDVVICRHLLWT 130

Query: 125 VADPRSVLQTLWSVLRPGGVLS 146
           +  P   ++    + RPGGV+ 
Sbjct: 131 LPHPDVAIREWSRICRPGGVII 152


>UniRef50_Q9NZJ6 Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial n=30
           Tax=Euteleostomi RepID=COQ3_HUMAN
          Length = 369

 Score =  129 bits (325), Expect = 9e-29,   Method: Composition-based stats.
 Identities = 45/214 (21%), Positives = 83/214 (38%), Gaps = 13/214 (6%)

Query: 4   RNFDDIAEKF--SRNIYGTTKG--QLRQAILWQDLDRVLAEMGPQK----LRVLDAGGGE 55
           + F  +A K+   + +Y        LR   +  +L + +    P K    +++LD G G 
Sbjct: 98  KTFLALAHKWWDEQGVYAPLHSMNDLRVPFIRDNLLKTIPNHQPGKPLLGMKILDVGCGG 157

Query: 56  GQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSD-NMQFIHCAAQDVASHLETPVD 114
           G     +   G  VI  D   + I  A+       V D  +++  C+ +++        D
Sbjct: 158 GLLTEPLGRLGASVIGIDPVDENIKTAQCHKSFDPVLDKRIEYRVCSLEEIVEETAETFD 217

Query: 115 LILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPK 174
            ++   V+E V D  + LQ    VL+PGG L +   N   L     +  + + +   +PK
Sbjct: 218 AVVASEVVEHVIDLETFLQCCCQVLKPGGSLFITTINKTQLSYALGIVFS-EQIAGIVPK 276

Query: 175 KKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
                 + +    P  +   LE  G  +    G+
Sbjct: 277 GTH---TWEKFVSPETLESILESNGLSVQTVVGM 307


>UniRef50_A4FIY5 Ubiquinone/menaquinone biosynthesis methyltransferase n=1
           Tax=Saccharopolyspora erythraea NRRL 2338
           RepID=A4FIY5_SACEN
          Length = 245

 Score =  129 bits (324), Expect = 1e-28,   Method: Composition-based stats.
 Identities = 60/226 (26%), Positives = 85/226 (37%), Gaps = 22/226 (9%)

Query: 4   RNFDDIA---EKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           RN+D  A    +F R      +   R A   + +   L   G   L VLD G G G  + 
Sbjct: 13  RNWDRRARDYNRFYRRFSADRRDAWRTA--CEKIVPALRPGGAGPLDVLDVGTGTGFLST 70

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
            +AE GH+V   D SA M+  A++ AE +GV  ++ F  C A DV   L +  DL+    
Sbjct: 71  LLAELGHRVTAVDPSATMLGYAREEAERRGV--DVSFRECGAHDV-EDLASTFDLVTARY 127

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHG---------LLMHNMVAGNFDYVQAG 171
           VL  +  P         VLRPGG + +     H            +       F +    
Sbjct: 128 VLWTLPAPVRATAAWSRVLRPGGAVLIADSTWHTWRGDGRRLLASLRPGGDHGFAWRLLR 187

Query: 172 MPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLRE 217
              +  R         P +    L   G+    + G R F D L E
Sbjct: 188 DYVRIGRATPNWKGLTPQRAQAILAAGGF----RRGER-FDDLLPE 228


>UniRef50_A0L9I8 3-demethylubiquinone-9 3-methyltransferase n=2 Tax=Proteobacteria
           RepID=A0L9I8_MAGSM
          Length = 241

 Score =  129 bits (324), Expect = 1e-28,   Method: Composition-based stats.
 Identities = 48/212 (22%), Positives = 86/212 (40%), Gaps = 17/212 (8%)

Query: 7   DDIAEKFSRNIYGTTKGQLRQAILWQ-------DLDRVL---AEMGPQKLRVLDAGGGEG 56
           D+IA KF R  +       +   L +        +  +L   A+     + +LD G G G
Sbjct: 8   DEIA-KFERMAHEWWDPAGKFRTLHEINPARVGYIKEILTGSAQGDLAGINLLDIGCGGG 66

Query: 57  QTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLI 116
             A  MA+ G  V+  D S ++I  A       G S + +    +A ++A       D++
Sbjct: 67  ILAEAMADNGANVVGIDRSEKIIGIATAHQAESGSSASYRMQ--SAAELAEAQPASFDVV 124

Query: 117 LFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKK 176
           L   VLE V D  + L    ++L+PGG L     N         + G  +Y+   +P+  
Sbjct: 125 LAMEVLEHVPDMTAFLGDCANLLKPGGTLFFATLNRTPKSWLFAIMGA-EYLLRWLPRGT 183

Query: 177 KRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
            +    +    P+++   L+  G ++    G+
Sbjct: 184 HQF---EKFVKPSELRTALQSNGLEMQAVRGL 212


>UniRef50_A8J700 C5-O-methyltransferase n=4 Tax=Streptomyces RepID=A8J700_9ACTO
          Length = 284

 Score =  128 bits (322), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 36/132 (27%), Positives = 62/132 (46%), Gaps = 2/132 (1%)

Query: 19  GTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE-RGHQVILCDLSAQ 77
           G+T GQ    +    + ++    G    RVLD G G G+ A+++A      ++   +S +
Sbjct: 45  GSTLGQASDRLTDHMIGKLREHTGRPVRRVLDVGCGSGRPALRLAHSEPVDIVGITISPR 104

Query: 78  MIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWS 137
            ++ A   AE  G+++ ++F    A D+    +   D +     L  + DP  V Q +  
Sbjct: 105 QVELATALAERSGLANRVRFECADAMDLP-FPDASFDAVWALECLLHMPDPARVFQEMAR 163

Query: 138 VLRPGGVLSLMF 149
           VLRPGG L+ M 
Sbjct: 164 VLRPGGRLAAMD 175


>UniRef50_A4Z3A6 Putative uncharacterized protein n=1 Tax=Bradyrhizobium sp. ORS278
           RepID=A4Z3A6_BRASO
          Length = 242

 Score =  128 bits (322), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 46/199 (23%), Positives = 82/199 (41%), Gaps = 7/199 (3%)

Query: 7   DDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERG 66
           D+IA  +   ++ +   + R A ++     +L +      R LDAG G G  +  +A RG
Sbjct: 20  DNIAANWE-TLHRSRTFRARTAAMFG----LLEQQDLSGQRWLDAGCGTGTLSRLLAGRG 74

Query: 67  HQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVA 126
            +V   D SA+MI RA+        +  ++F   A  +     +   D +L  +VLE+V 
Sbjct: 75  CEVTGVDASAEMIRRARHLPTGSEQTGALRFDQIATIEALPFSDGAFDGVLCASVLEYVP 134

Query: 127 DPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYP- 185
           D  + L+ +  VLR  G++ L   N    L+       F        +   R LS     
Sbjct: 135 DVPAALREIHRVLRVDGLVLLSIPNR-ASLLRQAFKLAFAVSSRAWTRPMFRYLSVSKFD 193

Query: 186 RDPAQVYLWLEEAGWQIMG 204
                    +++ G+ ++ 
Sbjct: 194 ASATTATHLMQDIGFSVLA 212


>UniRef50_UPI000186D07C hexaprenyldihydroxybenzoate methyltransferase, putative n=1
           Tax=Pediculus humanus corporis RepID=UPI000186D07C
          Length = 281

 Score =  128 bits (322), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 44/195 (22%), Positives = 84/195 (43%), Gaps = 10/195 (5%)

Query: 25  LRQAILWQDLDRVLAEMGPQKL---RVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDR 81
           +R  +++     V    GP+ L   ++LD G G G  +  +A  G  V   D   ++ID 
Sbjct: 71  VRDGLMYTKKADVENPNGPRPLNGVKILDVGCGGGILSEPLARIGADVTGIDPGQKLIDI 130

Query: 82  AKQAAEAKG-VSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLR 140
           AK  A     VS  ++++  + +D A+  +   D ++   V+E VA     L++  +VL+
Sbjct: 131 AKTHAAEDPTVSGKIRYLCESIEDHANGHKEKYDAVVASEVIEHVASKEIFLESCANVLK 190

Query: 141 PGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGW 200
           PGG + +   N         V    +Y+   +PK+       +    P ++    E+   
Sbjct: 191 PGGSIFITTINRTTQAWIAGVITA-EYLLHLVPKETHDW---EKFITPHELQFMCEKYDC 246

Query: 201 QIMGKTGVRVFHDYL 215
                 G+  F+++L
Sbjct: 247 FTKLVHGM--FYNFL 259


>UniRef50_C4XNC1 Putative 3-demethylubiquinone-9 3-methyltransferase n=1
           Tax=Desulfovibrio magneticus RS-1 RepID=C4XNC1_DESMR
          Length = 264

 Score =  128 bits (321), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 40/187 (21%), Positives = 73/187 (39%), Gaps = 11/187 (5%)

Query: 27  QAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAA 86
           +A  +  + R    +G     +LD G G G  A + A  G +V   D + + +  A+  A
Sbjct: 35  RANYFARVLRQEGLLGKTGATMLDVGCGGGLLAEEFARMGLRVTGVDPAPESVATARTHA 94

Query: 87  EAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLS 146
              G   ++ +     + +   ++   D +    VLE V +P +V+  +  VL+PGG+L 
Sbjct: 95  AEAGF--DIVYRVGRGEALP-FVDEAFDAVACCDVLEHVDEPAAVIAEMARVLKPGGLLL 151

Query: 147 LMFYNAHGLLMHNMVAGNFDY-----VQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQ 201
               N        ++    D+       AG+P +       D    PA+V   L      
Sbjct: 152 YDTVNRTLRSWFAVIKLMQDWPSTTVFDAGVPVQAHVW---DKFLKPAEVAAMLRRHDLD 208

Query: 202 IMGKTGV 208
              + G+
Sbjct: 209 PREQRGI 215


>UniRef50_Q467Y8 Methyltransferase n=2 Tax=Methanosarcina RepID=Q467Y8_METBF
          Length = 248

 Score =  128 bits (321), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 47/219 (21%), Positives = 96/219 (43%), Gaps = 37/219 (16%)

Query: 4   RNFDDI-AEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
           RN+    +E +S  I   ++ +      W+++     +   + L +LD G G GQ A+  
Sbjct: 8   RNYWGYRSETYSTGIVEQSEEEW---ATWKNILSSTVDR-REHLEILDVGTGPGQLALMF 63

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
           AE GH V   DLS +M+D+A++ A  + +  ++ FI   A+++    +   D++    +L
Sbjct: 64  AELGHHVTAVDLSTRMLDKARKNALKRSL--DINFIQGDAENL-QLPDMQFDVVSSKFLL 120

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMF---YNAHGLL-----------------MHNMVA 162
             + DP+  L     VL+  G++  +    +N+   L                  HN   
Sbjct: 121 WTLPDPQKALSEWKRVLKKDGMIIAIDGDWFNSGIFLKSIRTISDGIRSIKERNFHNPFN 180

Query: 163 GNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQ 201
            +++ ++  +P          Y   P +V+ +L + G++
Sbjct: 181 QHYNPIKKDLPL---------YSLKPDRVFRFLNDTGFE 210


>UniRef50_Q2NSL7 3-demethylubiquinone-9 3-methyltransferase n=305 Tax=Proteobacteria
           RepID=UBIG_SODGM
          Length = 249

 Score =  128 bits (321), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 47/204 (23%), Positives = 84/204 (41%), Gaps = 10/204 (4%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQ-KLRVLDAGGGEGQTAIKMAE 64
           FD +A ++  ++ G  K      I    LD +L   G      VLD G G G  A  MA 
Sbjct: 28  FDAVAARW-WDLEGEFKP--LHHINPLRLDYILERSGGLFGKNVLDVGCGGGILAESMAR 84

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
            G +V   D+ A+ +  A+  A   GV   + +     ++ A       D++    +LE 
Sbjct: 85  EGAKVTGLDMGAEPLAVARLHALESGVM--LAYHQQTVEEHAEAHPGAYDVVTCMEMLEH 142

Query: 125 VADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDY 184
           V DP S+++    +++PGG +     N +       + G  +YV   +P+          
Sbjct: 143 VPDPASIVRACARLVKPGGEVFFSTLNRNPKAWLMAIVGA-EYVLRMVPRGTHDI---TK 198

Query: 185 PRDPAQVYLWLEEAGWQIMGKTGV 208
              PA++  W+++   +     G+
Sbjct: 199 FIKPAELLGWVDDTPLREQHIIGL 222


>UniRef50_A5EVK0 Ubiquinone biosynthesis O-methyltransferase n=2
           Tax=Cardiobacteriaceae RepID=A5EVK0_DICNV
          Length = 231

 Score =  127 bits (320), Expect = 3e-28,   Method: Composition-based stats.
 Identities = 49/219 (22%), Positives = 92/219 (42%), Gaps = 11/219 (5%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
           +FD     F          +    I    +D +   +   +  +LD G G G  +  +A 
Sbjct: 11  SFDQYGAHFWDENGA---YRTLHHINPVRVDFIKQFIKLNQKTILDIGCGGGLLSEALAR 67

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
            G QV   DLS+ MI  A+     + ++  + +   ++ D  +  E   D I+   +LE 
Sbjct: 68  EGAQVFGIDLSSSMIAAAEHHLSGQNLA--INYRQISSHDCCAQNE-QYDHIVCMEMLEH 124

Query: 125 VADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDY 184
           VA+P ++L+ ++++LRP G   L   N +      M+    +Y+   +P+        D+
Sbjct: 125 VANPAAILRDIYALLRPNGFAFLSTVNRNKRAFFKMIVLA-EYLTKLVPRGTHHY--ADF 181

Query: 185 PRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRD 223
            R P ++    E AG   +  +G+  +H   +  H  R 
Sbjct: 182 IR-PHELVTMAERAGLSAVALSGM-TYHPLRKSAHLSRH 218


>UniRef50_O74421 Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial n=1
           Tax=Schizosaccharomyces pombe RepID=COQ3_SCHPO
          Length = 271

 Score =  127 bits (320), Expect = 3e-28,   Method: Composition-based stats.
 Identities = 50/206 (24%), Positives = 86/206 (41%), Gaps = 8/206 (3%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGP-QKLRVLDAGGGEGQTAIKMA 63
           +F+++A+ +     G+    L  +     +  V  E       ++LD G G G  +  MA
Sbjct: 37  HFNELAKTWWDWDGGSRLLHLMNSTRLDFMTEVFRERNCFSGKKILDIGCGGGILSESMA 96

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGV-SDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
             G  V   D S   I+ AK+ A    V +  +++IH + +   S L T  D++    VL
Sbjct: 97  RLGASVTAVDASPMAIEVAKKHASLDPVLNGRLEYIHGSVE--GSQLPTTFDVVTCMEVL 154

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSP 182
           E V  PR  L +L   ++P G L L   +   LL   +     ++V   +P       + 
Sbjct: 155 EHVEQPRDFLFSLMEKVKPNGRLVLSTISRT-LLARLLTITLAEHVLRIVPVGTH---TF 210

Query: 183 DYPRDPAQVYLWLEEAGWQIMGKTGV 208
           +      ++  +L+E  W I    GV
Sbjct: 211 EKFIRADELSNFLKEQNWIINDIRGV 236


>UniRef50_Q3SVP3 3-demethylubiquinone-9 3-methyltransferase n=45
           Tax=Alphaproteobacteria RepID=UBIG_NITWN
          Length = 261

 Score =  127 bits (320), Expect = 3e-28,   Method: Composition-based stats.
 Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 8/165 (4%)

Query: 44  QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQ 103
             LR+LD G G G         G QVI  D SA  I  AK  AE   +S  + +     +
Sbjct: 78  AGLRLLDIGCGAGLLCEPFTRLGAQVIGVDPSASNIAAAKLHAEKAHLS--IDYRCTTVE 135

Query: 104 DVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAG 163
           D+   +    D+IL   V+E VAD    L    ++L+PGG+++    N +       +  
Sbjct: 136 DMD--VRERFDIILAMEVVEHVADVGLFLDRCAAMLKPGGMMAASTLNRNWKSFALGIVA 193

Query: 164 NFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
             +YV   +P+   +    D    P ++    E  G  I  ++GV
Sbjct: 194 A-EYVLRWLPRGTHQW---DKFVTPDELARHFERNGLGITEQSGV 234


>UniRef50_B0A8V1 Putative uncharacterized protein n=1 Tax=Clostridium bartlettii DSM
           16795 RepID=B0A8V1_9CLOT
          Length = 255

 Score =  127 bits (320), Expect = 3e-28,   Method: Composition-based stats.
 Identities = 40/158 (25%), Positives = 75/158 (47%), Gaps = 7/158 (4%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEM--GPQKLRVLDAGGGEGQTA 59
            +R + D AE + +      +    + + W D+ +  A +  G ++L+VLD G G G  +
Sbjct: 10  NERYWADRAEGYCQVNIDELRSN--KKLEWIDIIKSNAPVFAGDRRLKVLDIGCGPGFFS 67

Query: 60  IKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFH 119
           I ++  G+ V   D + +M+++AKQ A    + D ++F    A ++    E   DLI+  
Sbjct: 68  IILSCAGYDVTAVDYTEEMLNKAKQNAGD--LKDKIKFRRMDAHNL-EFDEGQFDLIVTR 124

Query: 120 AVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLM 157
            +   + DP    ++ + VLR GG +     N +  L 
Sbjct: 125 NLTWNLKDPEKAYKSWYKVLRKGGKMINFDANWYLHLF 162


>UniRef50_Q48938 Orf3 protein n=3 Tax=Methanosarcina RepID=Q48938_METBA
          Length = 262

 Score =  127 bits (319), Expect = 4e-28,   Method: Composition-based stats.
 Identities = 47/214 (21%), Positives = 87/214 (40%), Gaps = 21/214 (9%)

Query: 1   MQDRNFDDIAEKFSRNI-YGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTA 59
           M    +D  +E F  +  +G    + R A  W+     L     + L++LD G G G+ +
Sbjct: 18  MVAHKWDLASETFDTHAGHGIQTQKERDA--WKR--AFLKVFPGKSLKILDVGCGTGELS 73

Query: 60  IKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFH 119
           +  AE GH+V   D+S QM+  AK  AEA G   ++ F    A++      +  D++   
Sbjct: 74  LLFAEMGHEVAGIDISGQMLKIAKAKAEALG--ADITFREGDAEN-PPFDTSSYDIVFSR 130

Query: 120 AVLEWVADPRSVLQTLWSVLRPGGVLSLMFY-------------NAHGLLMHNMVAGNFD 166
            +L  + +P+  ++    +LR  G + ++               NA  LL   +   +  
Sbjct: 131 HLLWTLPNPKVAVENWNRILRKNGKVVIVDGVWDSGTLGSRARKNAGALLTLLLERKDPR 190

Query: 167 YVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGW 200
              +    + K  L         +V  +L  +G+
Sbjct: 191 KGHSDYSDELKAQLPHFGGAPLEKVNEYLSNSGF 224


>UniRef50_Q012C7 Dihydroxypolyprenylbenzoate methyltransferase (ISS) n=1
           Tax=Ostreococcus tauri RepID=Q012C7_OSTTA
          Length = 351

 Score =  126 bits (318), Expect = 5e-28,   Method: Composition-based stats.
 Identities = 43/166 (25%), Positives = 69/166 (41%), Gaps = 6/166 (3%)

Query: 44  QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAK-GVSDNMQFIHCAA 102
           +  RVLD G G G  A  +A  G  V   D     I+ A+  A    G+   +++ H AA
Sbjct: 156 RGTRVLDVGCGGGIFAESLARLGADVTAIDAGLANIEIARAHAARDPGLDGRLRYEHVAA 215

Query: 103 QDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVA 162
           + +    ET  D +    V+E V+DP    ++L  ++RPGG L L   N         + 
Sbjct: 216 EALGDRGET-FDAVTSLEVIEHVSDPMGFAKSLGKLVRPGGALFLSTINRTARSFAFAIV 274

Query: 163 GNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
           G    +  G+      + S      P +V L    +G ++    G+
Sbjct: 275 GAERAL--GLVPPGTHSFS--KFLTPGEVALLASRSGCEMRELAGM 316


>UniRef50_D1BDI2 Methylase involved in ubiquinone/menaquinone biosynthesis n=1
           Tax=Sanguibacter keddieii DSM 10542 RepID=D1BDI2_SANKS
          Length = 296

 Score =  126 bits (318), Expect = 6e-28,   Method: Composition-based stats.
 Identities = 38/178 (21%), Positives = 84/178 (47%), Gaps = 10/178 (5%)

Query: 38  LAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQF 97
           L  +    + +LD G G G   + +A    +V+  D +  ++D A++ AE+ G + N+ F
Sbjct: 59  LVPLLRDDMTLLDVGCGPGTVTVDLARLVERVVGVDAATPVLDSARELAESTGTT-NVTF 117

Query: 98  IHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLM 157
            +  A ++    +   D++  H +L+ ++DP + ++ +  V +PGG+++    +   +  
Sbjct: 118 EYANAYELP-FDDDTFDVVHAHQLLQHLSDPIAAIREMRRVTKPGGIVAARDADYSAMTW 176

Query: 158 HNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPA-QVYLWLEEAGWQ---IMGKTGVRVF 211
           +   AG  ++         + T +  Y  D   ++  W +EAG+    + G  GV  +
Sbjct: 177 YPDSAGLTEW----NTLYHEVTAAYGYQADAGRRLLSWFQEAGFTPESLTGSAGVWCY 230


>UniRef50_Q033A8 SAM-dependent methyltransferase n=6 Tax=Firmicutes
           RepID=Q033A8_LACLS
          Length = 246

 Score =  126 bits (318), Expect = 6e-28,   Method: Composition-based stats.
 Identities = 52/254 (20%), Positives = 107/254 (42%), Gaps = 23/254 (9%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
             FD          + +   QL   ++W+ L    AE+     ++LD G G G  A  +A
Sbjct: 7   NYFDQ---------WESPWMQLYYRMVWEQLS---AEISLTDKKILDFGSGFGWNANHLA 54

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
           +R + VI  + +++M+   +Q       +++ Q I     ++    +   DLI+ H V E
Sbjct: 55  DR-NSVIAIEPNSEMVKNRQQ-------TNHYQQITGGLSELRKFNDEGFDLIICHNVFE 106

Query: 124 WVADPRS-VLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSP 182
           + +D R+ +L+    +L   G++S++ +N  G LM  +V  N       +     +T   
Sbjct: 107 YASDERAEILREFDRLLSKNGLISIVKHNYAGALMQKIVFENALDEAHDLLTGSSKTNQM 166

Query: 183 DYPRDPAQVYLWLE-EAGWQIMGKTGVRVFHDYLREKH-QQRDCYEALLELETRYCRQEP 240
                  ++   L  ++  +I    G+R F      +   + D  + + ++E   C +  
Sbjct: 167 FGKIHYYELADLLSTDSSLKIHKTYGLRTFWALQPNEFKIEPDWADKMFKVEWEVCDKPE 226

Query: 241 YITLGRYIHVTARK 254
           +  +  + H+  RK
Sbjct: 227 FAAISFFNHLILRK 240


>UniRef50_A5ZYR5 Putative uncharacterized protein (Fragment) n=1 Tax=Ruminococcus
           obeum ATCC 29174 RepID=A5ZYR5_9FIRM
          Length = 796

 Score =  126 bits (316), Expect = 8e-28,   Method: Composition-based stats.
 Identities = 48/204 (23%), Positives = 84/204 (41%), Gaps = 6/204 (2%)

Query: 11  EKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGP--QKLRVLDAGGGEGQTAIKMAERGHQ 68
           EK S +     + +L  A+  + +  + A++    +KLR+LD G G G   I +A+ GHQ
Sbjct: 589 EKRSDSFLEQRRAELHSAMADRWMKEIQAQLPDDNKKLRILDVGCGAGFFTILLAKAGHQ 648

Query: 69  VILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADP 128
           V   DL+  MI  A+  A+ +G   + +F    A++     +   D+I+   +   +   
Sbjct: 649 VTGIDLTPDMIKNARILAQEEG--ADCEFTVMDAEN-PEFPDDTFDVIISRNLTWTLPHV 705

Query: 129 RSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDP 188
           R   Q    VLR GGVL     N       N+     ++    +  +  R       + P
Sbjct: 706 RHAYQEWLRVLRKGGVLLNFDANYGITDFSNVEDLPENHAHNMLGNEMMRECEEIKRQLP 765

Query: 189 AQVYLWLEEAGWQIMGKTGVRVFH 212
              Y        + +G   ++ FH
Sbjct: 766 ISSYS-RPAWDLETLGAMSLKEFH 788



 Score =  125 bits (314), Expect = 1e-27,   Method: Composition-based stats.
 Identities = 41/168 (24%), Positives = 73/168 (43%), Gaps = 10/168 (5%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQD-----LDRVLAEMGPQKLRVLDAGGGEGQTA 59
            + + A  +S   Y   +    +  +W+D     L     E  P ++++LD G G G  A
Sbjct: 11  YWTNRARGYSE--YNQQEMADARRTMWRDKLLSLLGEAFPEREPGEIKILDVGTGPGFFA 68

Query: 60  IKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFH 119
           I +AE G+QV   D + +M+  A+Q A   G+++ + +    AQ +        D I+  
Sbjct: 69  ILLAEAGYQVTAVDYTEEMLREAQQNA--GGLAECIVWKTGDAQALDVES-NSFDAIVTR 125

Query: 120 AVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDY 167
            V   +  P    +    VL+PGGVL     + +G L +      ++ 
Sbjct: 126 NVTWNLPRPDLAYKEWLRVLKPGGVLYNFDADWYGHLYNEEKRSGYEK 173


>UniRef50_D1YW16 ABC transporter ATP binding protein n=3 Tax=Methanocella paludicola
           SANAE RepID=D1YW16_METPS
          Length = 572

 Score =  126 bits (316), Expect = 9e-28,   Method: Composition-based stats.
 Identities = 47/214 (21%), Positives = 84/214 (39%), Gaps = 16/214 (7%)

Query: 1   MQD-----RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGE 55
           M D     + +D +++K+   + GT    LR       L+++  E G    R ++ G G 
Sbjct: 6   MADTGAGIKFWDAVSQKYDNAVDGTMGKNLRPT----ALEKLSQEAGLG--RAVELGCGT 59

Query: 56  GQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDL 115
           G     +A     V+  D    M+ RA +   + G   N+ F         S  +   D 
Sbjct: 60  GYFTKTLARVADSVVATDFCEGMLARAMERLSSAG---NITFQKEDCMK-TSFPDDTFDT 115

Query: 116 ILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKK 175
           +L   VL ++ DP + L     +L+PGG L ++  + +  +       +   + AG    
Sbjct: 116 VLMALVLNYIPDPAAALAEARRILKPGGRLIIVNPD-NSFIGEARKRLSSYKLMAGYGDA 174

Query: 176 KKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVR 209
           + R            +Y  LE AG++I     +R
Sbjct: 175 QVRYPQTFRNLSADGLYKMLETAGFKIEASELIR 208


>UniRef50_Q89BX8 Bll8020 protein n=1 Tax=Bradyrhizobium japonicum RepID=Q89BX8_BRAJA
          Length = 299

 Score =  126 bits (316), Expect = 1e-27,   Method: Composition-based stats.
 Identities = 54/216 (25%), Positives = 91/216 (42%), Gaps = 22/216 (10%)

Query: 35  DRVLAEMGPQKLR-VLDAGGGEGQTAIKMAERGH--QVILCDLSAQMIDRAKQAAEAKGV 91
           D +L  + P K   VLD   G G  A ++AERGH  +++  DL+  M+  A+        
Sbjct: 58  DDLLDRIDPAKGECVLDVACGTGVVARRLAERGHVGRLVGIDLNGAMLAVARAK------ 111

Query: 92  SDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYN 151
           S ++++   +A D+        D++L    L++  D    L+ +  VL+P G L L  Y+
Sbjct: 112 SSDVEWTEGSALDLP-FATRSFDVVLCQLGLQFFPDRPQALREMARVLKPSGRLGLSVYS 170

Query: 152 AHGLLMHNMVAGNFDYVQAGM--PKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKT--- 206
           A   + H   A  F     G   P+  +   +     +  +V  W+ +AG+  +G     
Sbjct: 171 A---IEHTPAANAFVQALDGFLGPESSRTKRAEHLTCNADEVGNWVRQAGFDRVGVETVT 227

Query: 207 ---GVRVFHDYLREKHQQRDCYEALLELETRYCRQE 239
              G     DY+R +        ALL  E    R+ 
Sbjct: 228 KQIGFPSALDYVRFQLTAT-PMAALLTREDDAGRER 262


>UniRef50_Q8TPQ8 UbiE/COQ5 methyltransferase n=1 Tax=Methanosarcina acetivorans
           RepID=Q8TPQ8_METAC
          Length = 208

 Score =  126 bits (316), Expect = 1e-27,   Method: Composition-based stats.
 Identities = 50/208 (24%), Positives = 87/208 (41%), Gaps = 18/208 (8%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
           R + D AE     I         +  LW ++   L     Q+L++LD G G G  A+ +A
Sbjct: 8   RAWWDTAEHDYDAIAAHGVHSEEERELWTEVITQLL-GSDQQLKILDMGTGTGFLALLLA 66

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
           E G++V   D +A  +++AK+  E  G  + + F+   A++++   E   D ++   ++ 
Sbjct: 67  ELGYEVTGADWAASKLEKAKKKMERTG--NFVNFVVEDAENLSFESE-QFDAVVSRHLVW 123

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPD 183
            +A+P S  +    V +PGG +     + H    H       + +   +P          
Sbjct: 124 TLANPDSAFKEWARVTKPGGKVLTDIPSRHS---HPGNHHFGEEIGKELPFY-------- 172

Query: 184 YPRDPAQVYLWLEEAGWQIMGKTGVRVF 211
              DP  V    E AG   +    VRVF
Sbjct: 173 NGADPGDVISMFEAAGLVNVS---VRVF 197


>UniRef50_B7FTF3 Predicted protein (Fragment) n=1 Tax=Phaeodactylum tricornutum CCAP
           1055/1 RepID=B7FTF3_PHATR
          Length = 249

 Score =  126 bits (316), Expect = 1e-27,   Method: Composition-based stats.
 Identities = 39/169 (23%), Positives = 69/169 (40%), Gaps = 5/169 (2%)

Query: 44  QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQ 103
           +   VLD G G G  +  +A  G  V   D S +++D A+   +    + N+ ++     
Sbjct: 57  EGKTVLDIGCGGGLLSESLARLGATVTAIDPSQRLVDAARLHGQLDRRTRNINYLGNTTA 116

Query: 104 DVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAG 163
           +  S      D++    V+E   DP S+++   S+++PGG L L   N         + G
Sbjct: 117 EDLSQTGDKFDVVCLLEVIEHATDPDSLVEAAASMVKPGGYLFLSTLNKTIKSYLLTIVG 176

Query: 164 NFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFH 212
             +Y+   +P              PAQV       G + +  +G+ V H
Sbjct: 177 A-EYIMGYIPPGTHDW---KQYLSPAQVGEMTSRNGLRPVDVSGL-VLH 220


>UniRef50_D2LFP9 Ubiquinone biosynthesis O-methyltransferase n=1 Tax=Rhodomicrobium
           vannielii ATCC 17100 RepID=D2LFP9_RHOVA
          Length = 252

 Score =  125 bits (315), Expect = 1e-27,   Method: Composition-based stats.
 Identities = 50/215 (23%), Positives = 89/215 (41%), Gaps = 18/215 (8%)

Query: 4   RNFDDIAEKFSRNIYGTTKG-----QLRQAILWQDLDRV----LAEMGP-QKLRVLDAGG 53
           R+F+ +A+++     G   G       R A +  ++ R       E  P Q L V+D G 
Sbjct: 19  RHFESLAKEWWDE-RGKFSGLHAFNPARLAFIVAEVKRWRKGQFNEFRPLQGLDVVDIGC 77

Query: 54  GEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPV 113
           G G  +  +A  G  V   D   + +  A+  A   G    + + +  A+D+A       
Sbjct: 78  GGGILSEPLARLGGTVTGIDPVEESVGVARAHAAKLGAP--VTYRNVTAEDLAREG-LTF 134

Query: 114 DLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMP 173
           D+++   V+E VADP+S L+T  S+ +PGG++ L   N         V    + +   +P
Sbjct: 135 DVVVASEVIEHVADPQSFLKTCRSLAKPGGLIVLSTLNRTSKSYGLAVFAA-ERILGLVP 193

Query: 174 KKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
                         P ++   L +AG+    + G+
Sbjct: 194 PGTHDW---KKFIKPDELAGALSDAGFAATRRAGM 225


>UniRef50_Q46F92 Putative uncharacterized protein n=2 Tax=Methanosarcina
           RepID=Q46F92_METBF
          Length = 249

 Score =  125 bits (314), Expect = 1e-27,   Method: Composition-based stats.
 Identities = 39/148 (26%), Positives = 66/148 (44%), Gaps = 10/148 (6%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLR--VLDAGGGEGQTAIK 61
             ++  A+ +S  I     G  R+A  W DL   + E  P K R  +LD G G G   I 
Sbjct: 9   NYWEGEAQGYSEAIEDELNGFERKA--WSDL---VLEYAPSKDRLDILDIGTGPGFFPIV 63

Query: 62  MAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
           +++ GH V   DL+  MI+ A+     +G S  +  +    Q++    +   DL++   +
Sbjct: 64  LSQGGHNVTGIDLTENMIEFARLNLAREGASAKL--VTMDCQNL-KFPDNCFDLLVCRNL 120

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMF 149
              + DP    +    VL+PGG + +  
Sbjct: 121 TWTLDDPAKAYKEWHRVLKPGGRVLIFD 148


>UniRef50_B0XJ66 3-demethylubiquinone-9 3-methyltransferase n=2 Tax=Culicini
           RepID=B0XJ66_CULQU
          Length = 306

 Score =  125 bits (314), Expect = 2e-27,   Method: Composition-based stats.
 Identities = 41/175 (23%), Positives = 74/175 (42%), Gaps = 8/175 (4%)

Query: 44  QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAE--AKGVSDNMQFIHCA 101
           + +R+L+AG G G  A  +A  G  V+  D   +MID AK+  E  +  + D +++    
Sbjct: 118 KGVRILEAGCGGGVLAEDLARLGAYVVGVDPGTEMIDLAKRHLETESADLKDRLEYHAIT 177

Query: 102 AQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMV 161
            ++ A       D I+   V+E V +   +L+     L+PGG L +   N   L     +
Sbjct: 178 VEEHAKKFAGTYDAIVCSEVMEHVDEKVPILEACVRCLKPGGSLFVTTENQTMLAWFMFI 237

Query: 162 AGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLR 216
               +Y+   +PK        +    P Q+   L++   +     G   F+D + 
Sbjct: 238 II-PEYILKFIPKGTHFY---EKFVSPGQISKILDQYQCKTKRVRGF--FYDRMF 286


>UniRef50_Q73R34 Methlytransferase, UbiE/COQ5 family n=1 Tax=Treponema denticola
           RepID=Q73R34_TREDE
          Length = 250

 Score =  125 bits (313), Expect = 2e-27,   Method: Composition-based stats.
 Identities = 35/131 (26%), Positives = 59/131 (45%), Gaps = 1/131 (0%)

Query: 44  QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQ 103
           +  +VLDAG G G  AI +A+ G +V   D S  M++  K+ AE  G+SD + F+   A 
Sbjct: 44  KGKKVLDAGCGTGFLAILLAQDGWEVTAIDSSEAMLEEGKKTAEELGLSDKITFLLKDAH 103

Query: 104 DVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAG 163
                 E   D ++          P +V +    +L+PGG++  +  N    + +     
Sbjct: 104 S-TDFPEHLFDAVVSRHASWLFTAPETVYKEWKRILKPGGIMLNIDANWLKPIWNTDEFE 162

Query: 164 NFDYVQAGMPK 174
            F   +A + K
Sbjct: 163 KFKSYEAELVK 173


>UniRef50_Q8TNX2 Putative uncharacterized protein n=1 Tax=Methanosarcina acetivorans
           RepID=Q8TNX2_METAC
          Length = 256

 Score =  125 bits (313), Expect = 2e-27,   Method: Composition-based stats.
 Identities = 44/216 (20%), Positives = 93/216 (43%), Gaps = 22/216 (10%)

Query: 6   FDDIAEKFSRN-IYGTTKGQLRQAILWQD-LDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
           + + A ++++  IY     +  +A  W++ L  +L +   + +RVLDAG G G  ++ +A
Sbjct: 7   WSNAALEYNKKTIYDFDNEKTNRA--WREVLVDILGQ--KENMRVLDAGSGTGFLSMLLA 62

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
             GH V+  + +  M+  A + A  +G+  ++ F+     ++    +   D +L   ++ 
Sbjct: 63  TMGHSVVGVERAPNMLKIASENAVNRGL--HVDFVLGDVYNLQMIEQDSFDALLSRYLVW 120

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLL-------MHNMVAGNFDYVQAGMPKKK 176
            +  P    +    VL+PGG L ++  N +  L       M   ++   D+V  G   + 
Sbjct: 121 TLESPEKAFREWLRVLKPGGRLIIIDANWYPNLSRSPFLKMWRKMSWLLDFVTEGKKLRG 180

Query: 177 KRT-------LSPDYPRDPAQVYLWLEEAGWQIMGK 205
           +         L       P +    LE  G++++  
Sbjct: 181 RGEGDVAFYNLPFSRVERPEEDVRLLELCGYRVLEI 216


>UniRef50_Q2RJ99 UbiE/COQ5 methyltransferase n=1 Tax=Moorella thermoacetica ATCC
           39073 RepID=Q2RJ99_MOOTA
          Length = 230

 Score =  125 bits (313), Expect = 2e-27,   Method: Composition-based stats.
 Identities = 39/155 (25%), Positives = 75/155 (48%), Gaps = 7/155 (4%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M +  FD  A  +  + Y    G L   +  + +   L     +   +LD G G G  ++
Sbjct: 1   MAE-IFDRKAGDYD-DWYTRPLGALVDRVEKEPIYAYLDPHAGEH--ILDVGCGTGNFSL 56

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
           ++A RG +V   D+S  M+ +A++ A   G++  ++F+H  A ++    +   D I+   
Sbjct: 57  ELARRGVKVTGIDISDPMLAKARKKAADAGLA--IEFLHADAMNLP-FGDNTFDKIVSVT 113

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGL 155
            LE+  D ++VL+  + VL+PGG + +     + L
Sbjct: 114 ALEFAPDLKAVLEESYRVLKPGGRMVIGLIGGNSL 148


>UniRef50_C6CNR0 Methyltransferase type 11 n=2 Tax=Dickeya RepID=C6CNR0_DICZE
          Length = 265

 Score =  124 bits (312), Expect = 3e-27,   Method: Composition-based stats.
 Identities = 38/163 (23%), Positives = 69/163 (42%), Gaps = 8/163 (4%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKL-RVLDAGGGEGQTAIKM 62
             +++ AE ++        G  R+  LWQ++  +L     + L  +LD G G G  A+ +
Sbjct: 25  HYWNNRAEGYNEVNVAELAGGKRR--LWQEI--ILRHAPKKPLLNILDVGTGPGFFAVTL 80

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
           A  GH+V   D++  M+ +A+  A+   V   + F+      +    +   D+++   V 
Sbjct: 81  AMAGHRVTAVDVTPAMLAQARSNADYYDVE--IAFVATDVHALP-FPDNHFDVLVTRNVT 137

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNF 165
             +  P S  Q    VL PGG L     N +  L +      +
Sbjct: 138 WNLKQPLSAYQEWHRVLAPGGRLINFDANWYAHLFNAAAREGY 180


>UniRef50_B9M2E9 Ubiquinone biosynthesis O-methyltransferase n=1 Tax=Geobacter sp.
           FRC-32 RepID=B9M2E9_GEOSF
          Length = 258

 Score =  124 bits (311), Expect = 3e-27,   Method: Composition-based stats.
 Identities = 37/211 (17%), Positives = 73/211 (34%), Gaps = 15/211 (7%)

Query: 41  MGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHC 100
            G Q    L+ G G G  + ++A  G      D SA  +  A   A+A G+S  + ++  
Sbjct: 36  HGRQGGTALEVGCGGGILSEEIAALGFTTTGIDPSAAALQVAADHAKAGGLS--IGYLQA 93

Query: 101 AAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNM 160
             +++    +   D+     VLE V D    +  +  VL+PGG+      N         
Sbjct: 94  VGENLP-FPDNSFDVAFCCDVLEHVQDQTRTVAEIARVLKPGGIFCYDTINRTLASWLVA 152

Query: 161 VAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQ 220
           +     + +  +   +    + +    P ++ + LE++        G++           
Sbjct: 153 IGVLQKWKRWAVMPPELH--TWNKFIKPEELKMLLEKSHLGWREHRGIK----------P 200

Query: 221 QRDCYEALLELETRYCRQEPYITLGRYIHVT 251
                  L  L  R   +  Y  L   + + 
Sbjct: 201 ATSPIRTLSYLRRRARGEWNYKDLALRLQLI 231


>UniRef50_C5RP33 Methyltransferase type 11 n=1 Tax=Clostridium cellulovorans 743B
           RepID=C5RP33_CLOCL
          Length = 260

 Score =  124 bits (311), Expect = 3e-27,   Method: Composition-based stats.
 Identities = 54/261 (20%), Positives = 111/261 (42%), Gaps = 17/261 (6%)

Query: 8   DIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAE-MGPQKLRVLDAGGGEGQTAIKMAERG 66
           ++ E +  NIY   +   R  + +    R L + +  + L V D GGG G+ +  +AE+G
Sbjct: 2   NVIENYYDNIYDEWERLERHKLEFDITKRYLDKYIIGESLEVFDIGGGPGRYSFYLAEKG 61

Query: 67  HQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV- 125
           H+V L DLS++ I+ AK+ A+   V    ++I+  A ++    E   D+IL    L  + 
Sbjct: 62  HKVSLLDLSSRNIEVAKEKAKEFNVGLK-EYIYGNALEL-EKYEQKYDVILLMGPLYHLV 119

Query: 126 -ADPRS-VLQTLWSVLRPGGVLSLMFYNAHGLLMH--------NMVAGNFDYVQAGMPKK 175
             D R   ++    +L+PGG++   F + +  +          N +     Y+++G  + 
Sbjct: 120 KEDQRKLAVEGALRLLKPGGIIFATFISNYAPIQDALKYFYEINDIQDVLRYLKSGENRP 179

Query: 176 KKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREK--HQQRDCYEALLELET 233
           ++   +  Y   P++    +     + +    V        ++      + Y+  +E+  
Sbjct: 180 EEG-FTSAYFSSPSEAKSLMSSYYIKELVFASVENILGSKEKELYSLSDEQYKKWIEIGF 238

Query: 234 RYCRQEPYITLGRYIHVTARK 254
           R    +  I  G +     +K
Sbjct: 239 RLSTDKNLIGTGEHFLYIGQK 259


>UniRef50_A2SPT6 Methyltransferase type 11 n=2 Tax=Methanomicrobiales
           RepID=A2SPT6_METLZ
          Length = 257

 Score =  124 bits (311), Expect = 3e-27,   Method: Composition-based stats.
 Identities = 52/279 (18%), Positives = 99/279 (35%), Gaps = 45/279 (16%)

Query: 1   MQD-RNFDDIAEKFSR--NIYGTTKGQ----LRQAILWQDLDRVLAEMGPQKLRVLDAGG 53
           M D +   +IA  +++  N Y +          +  LW +      +   Q L+VLD G 
Sbjct: 1   MNDEKIKQEIANAWNQESNFYDSHVSHGMKSDEEKKLWMEAFSTRVKNDTQ-LQVLDVGC 59

Query: 54  GEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPV 113
           G G   +  AE GH V   DLS  M+D  ++ A    ++ N  F    A+      +   
Sbjct: 60  GTGAMGLIFAEMGHTVEGIDLSEGMMDVGRKKAADMHLAMN--FSSGDAEH-PPFDDGKF 116

Query: 114 DLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMP 173
           D+++   +L  + +P   + + + VL+P G L ++          N V     +  A + 
Sbjct: 117 DVVVNRHLLWTLPNPDKAISSWFRVLKPNGTLLVIDGVWDDGSRLNTVKKKISHKIASLV 176

Query: 174 KKKKR------------TLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQ 221
           +                 L         +   + E AG+  +    +    D       +
Sbjct: 177 EAHPHGGKSRYSEEVSSYLPNKGGTSEEKAKEYFENAGFTNITVVNLDAITD-------E 229

Query: 222 RDCYEALLELETRYCRQEPYITLG---RYIHVTARKPQS 257
           +  Y +             Y+ +     Y  ++ +KP+S
Sbjct: 230 QRKYFSW------------YMKIAPKSTYYLISGKKPES 256


>UniRef50_C1MP91 Predicted protein n=1 Tax=Micromonas pusilla CCMP1545
           RepID=C1MP91_9CHLO
          Length = 366

 Score =  124 bits (311), Expect = 3e-27,   Method: Composition-based stats.
 Identities = 37/176 (21%), Positives = 66/176 (37%), Gaps = 6/176 (3%)

Query: 35  DRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAE-AKGVSD 93
           D          LRVLD G G G     +A  G  V   D   + ID AK+ A     +  
Sbjct: 160 DAARDARPLAGLRVLDVGCGGGILCESLARMGADVTGIDAGKRNIDIAKKHASLDPAIDA 219

Query: 94  NMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAH 153
            + +    A+++ +      D +L   V+E V +P + +++L  + RPGG + +   N  
Sbjct: 220 KITYHAAPAEELLASG-ASFDAVLSMEVVEHVDNPETFVKSLHGLTRPGGAVVMSTLNRT 278

Query: 154 GLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVR 209
                  +    + +   +P              P ++ +    AG  +    G+R
Sbjct: 279 ARSYALAIVAA-ERIMGWVPPGTHEF---GKFLTPEELTVLFRRAGLTLREAAGMR 330


>UniRef50_B8FRY0 Methyltransferase type 12 n=2 Tax=Desulfitobacterium hafniense
           RepID=B8FRY0_DESHD
          Length = 242

 Score =  124 bits (311), Expect = 3e-27,   Method: Composition-based stats.
 Identities = 45/197 (22%), Positives = 79/197 (40%), Gaps = 15/197 (7%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M +  FD +A  +  + Y T  G L   +  +    +    GPQ   VL+ G G GQ   
Sbjct: 1   MNEALFDPVAAHYD-SWYDTELGSLSDQVERRLAQSMFKAPGPQ---VLEIGCGTGQYTS 56

Query: 61  KMAERGHQVILCDLSAQMIDRAKQA-AEAKGVSDNMQFIHCAAQDVASHLE--TPVDLIL 117
            + + G++V   D+S +M+  A++  A  +  +   + +H    D+   L+     D I 
Sbjct: 57  WLLQEGYEVTAVDISGKMMALAQKKIATLQETTPQAKPVHWWHGDITEILDQLGTYDGIF 116

Query: 118 FHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKK 177
                E+V +P +VL+ L+S L PGG L +                  DY +    +K  
Sbjct: 117 SMTAFEFVPEPETVLKKLFSRLNPGGCLLIGLIAGESAWS--------DYYEEAARRKPA 168

Query: 178 RTLSPDYPRDPAQVYLW 194
              +        ++  W
Sbjct: 169 SVFARAALYTKEEIASW 185


>UniRef50_C6C7H1 Methyltransferase type 11 n=3 Tax=Enterobacteriaceae
           RepID=C6C7H1_DICDC
          Length = 258

 Score =  124 bits (311), Expect = 4e-27,   Method: Composition-based stats.
 Identities = 41/155 (26%), Positives = 69/155 (44%), Gaps = 8/155 (5%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQK-LRVLDAGGGEGQTAIKM 62
           R +   A  +S+   G     + +  +W  L ++L +   +  LRVLD G G G  A+ +
Sbjct: 18  RYWRGRAADYSQINIGEL--AMPKRAVW--LAKILEQAPQKPVLRVLDIGTGPGFFAVTL 73

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
           A  GH+V   D++  M+D+A+  A     +  + F+H     +    +   DL++   V 
Sbjct: 74  ALAGHRVTAVDVTQAMLDQARANAAHYRTT--IDFVHSDVHALP-FADNGFDLVVSRNVT 130

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLM 157
             + DP+   Q    VL PGG L     N +  L 
Sbjct: 131 WNLTDPQRAYQEWRRVLAPGGRLINFDANWYLQLF 165


>UniRef50_Q465A3 UbiE/COQ5 methyltransferase n=3 Tax=Methanomicrobia
           RepID=Q465A3_METBF
          Length = 230

 Score =  124 bits (311), Expect = 4e-27,   Method: Composition-based stats.
 Identities = 47/233 (20%), Positives = 93/233 (39%), Gaps = 23/233 (9%)

Query: 1   MQDR---NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQ 57
           M+D+   +++ I+  + R +Y     +    +    LD++ A    +KL VLD G G G 
Sbjct: 1   MKDKITAHWNKISPNY-RKMYRDHLDEEILLMQNLFLDKLPA---GKKLNVLDIGTGPGI 56

Query: 58  TAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLIL 117
            A   A  GH V   D+S +M+ RAK+ A+ + +S  ++F+    + +        D+I+
Sbjct: 57  QAFVFAGMGHNVTALDISEEMLARAKEEAKNRNLS--IKFVEGDGEKLPFE-NNTFDIIV 113

Query: 118 FHAVLEWVADPRSVLQTLWSVLRPGGVLSLMF-----YNAHGLLMHNMVAGNFDYVQAGM 172
              +L  + D          VL P G +  +             ++N    N D +   +
Sbjct: 114 NMHLLWTLTDHDKFFSECCRVLVPEGRILAIDGQWFQPGYVPNRIYNQEERNHDELIEYL 173

Query: 173 PKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCY 225
           P     +        P  +   +E  G+  +    +  + +Y++    +   Y
Sbjct: 174 PLYDSNS--------PEMITTIMENNGFSEVSWKSLPEYAEYMKRCDPEGYDY 218


>UniRef50_D1CAG8 Methyltransferase type 11 n=1 Tax=Sphaerobacter thermophilus DSM
           20745 RepID=D1CAG8_SPHTD
          Length = 286

 Score =  124 bits (311), Expect = 4e-27,   Method: Composition-based stats.
 Identities = 59/262 (22%), Positives = 102/262 (38%), Gaps = 25/262 (9%)

Query: 13  FSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILC 72
           +       T G+L +A +W+ LD           RVLD G G G+ A+++A+RG  V+  
Sbjct: 15  YDAVFTHRTLGRLLRAAVWEHLDAAFHP----GDRVLDLGCGTGEDAVRLAQRGIDVLAT 70

Query: 73  DLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPV---DLI----LFHAVLEWV 125
           D+SA MI  A++ A   GV++ +       ++    L       D I         L  +
Sbjct: 71  DVSAGMIAVAREKAADAGVAERVHLAQVDLREHPLSLPASWRGPDGIDGSFSSFGALNCL 130

Query: 126 ADPRSVLQTLWSVLRPGGVLSLMFYNAH--GLLMHNMVAGNFDYVQAGMPKKKKRTLSPD 183
            D R +  TL + +RPGG L L+         +  +M  G        +   +  TL+  
Sbjct: 131 PDRRRLASTLAAWIRPGGRLVLVLMGPLCPWEIGWHMARGQPRRAVRRLTAGRDGTLAHT 190

Query: 184 --------YPRDPAQVYLWLEEAGWQIMGKTGVRVFHD--YLREKHQ-QRDCYEALLELE 232
                   +   P ++      A ++ +   G+ V     YL    + Q   +  L  LE
Sbjct: 191 GGGTSVRVWYPTPRRLRAEFAPA-FRHVRTVGIGVLLPPSYLAGLVECQPRAFTRLAALE 249

Query: 233 TRYCRQEPYITLGRYIHVTARK 254
            R   + P+  L  +  +   +
Sbjct: 250 RRIAGRFPWPWLADHYLMVLER 271


>UniRef50_Q21DX2 Methyltransferase type 11 n=2 Tax=Gammaproteobacteria
           RepID=Q21DX2_SACD2
          Length = 212

 Score =  123 bits (310), Expect = 5e-27,   Method: Composition-based stats.
 Identities = 45/205 (21%), Positives = 91/205 (44%), Gaps = 22/205 (10%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIK 61
            ++ ++  AE ++++          +    + L    + + P K+R+L+ G G G TAI 
Sbjct: 8   SEKYWNKKAEGYAKSPVSD------EETYKRKLTETQSFLQP-KMRLLEFGCGTGTTAIH 60

Query: 62  MAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
            A     +   D+S  M++  ++ A   GV+ N+ F      +  +     +D +L   V
Sbjct: 61  HASHVLHIDAIDISENMLNIGREKASNAGVA-NITFTRSTLTEFNA-GAASLDAVLGLNV 118

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGN--FDYVQAGMPKKKKRT 179
           +  + D +SVL  +  +L+PGGV           +   +  GN  F +++  +P  K   
Sbjct: 119 IHLLPDRQSVLTEVARILKPGGVF----------VSSTVCLGNSYFRFIKPFVPLGKFLG 168

Query: 180 LSPD-YPRDPAQVYLWLEEAGWQIM 203
           + PD Y    +++   + +AG+ I 
Sbjct: 169 VMPDVYVLTESELASEVRDAGFTIE 193


>UniRef50_Q5WW02 3-demethylubiquinone-9 3-methyltransferase n=4 Tax=Legionella
           pneumophila RepID=Q5WW02_LEGPL
          Length = 230

 Score =  123 bits (310), Expect = 5e-27,   Method: Composition-based stats.
 Identities = 48/217 (22%), Positives = 86/217 (39%), Gaps = 14/217 (6%)

Query: 11  EKFSR--NIYGTTKGQLR--QAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERG 66
            KF++  N +  T G LR    I     + +   +  + LRVLD G G G     MA+ G
Sbjct: 14  HKFAQLANDWWDTNGPLRTLHDINGTRFEFISEHINLKGLRVLDVGCGGGILCESMAKAG 73

Query: 67  HQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVA 126
             V   D   + I  AK+ A    +   + +     ++   +     D+I    +LE V 
Sbjct: 74  AYVSGLDAEPEAIQVAKEHAHKNQL--QIDYFCNPIEE---YENQGFDVITCMELLEHVQ 128

Query: 127 DPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPR 186
           +P  VLQ    +L+P G+L L   +         +    +YV   +P++       D   
Sbjct: 129 NPELVLQHCKRLLKPNGLLFLSTISRTLKAYLGAIIAA-EYVLNLLPRQTHDY---DKFI 184

Query: 187 DPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRD 223
            P+++          ++   G+  ++ +LR+     D
Sbjct: 185 KPSELVKMARLYDLNLIDMKGL-CYNPFLRKTTLVSD 220


>UniRef50_B4RRL2 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase
           n=1 Tax=Alteromonas macleodii 'Deep ecotype'
           RepID=B4RRL2_ALTMD
          Length = 250

 Score =  123 bits (310), Expect = 5e-27,   Method: Composition-based stats.
 Identities = 43/212 (20%), Positives = 89/212 (41%), Gaps = 16/212 (7%)

Query: 6   FDDIAEKF----SRNIYGTTKGQLRQAILWQDLDRVLAEMGPQK----LRVLDAGGGEGQ 57
           FD +A+ +     +        + R  ++   ++    +         L ++D G G G 
Sbjct: 21  FDALADSWWDPSGKYKTALEFNRARLTVIKTQIENHFGKGNLPPDYSALSIIDIGSGGGL 80

Query: 58  TAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLIL 117
            +  +A  G +V   D S+  ++ AK+ A   GV  ++++ H  + + A       D+++
Sbjct: 81  ISEPLAALGAKVTGIDASSVSVEVAKRHALKSGV--DVEYKHMLSSE-AVMTGQQYDVVI 137

Query: 118 FHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKK 177
              V+E V D R ++    S+++PGG+L L   N         + G  +YV   +P    
Sbjct: 138 NAEVVEHVPDQRQLINECASLVKPGGLLILATLNRTIKSYVIAIVGA-EYVMRYLPVGTH 196

Query: 178 RTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVR 209
                     P ++  W+ +  + +  +TG+R
Sbjct: 197 DW---RKFVKPQELQAWVGD-RFALKHQTGMR 224


>UniRef50_C8W4V3 Methyltransferase type 11 n=1 Tax=Desulfotomaculum acetoxidans DSM
           771 RepID=C8W4V3_DESAS
          Length = 249

 Score =  123 bits (309), Expect = 6e-27,   Method: Composition-based stats.
 Identities = 47/196 (23%), Positives = 77/196 (39%), Gaps = 11/196 (5%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
           +  +   A ++S NI+       + A  W  L       G + L+VLD G G G  A+ +
Sbjct: 8   ENYWQGAASRYSNNIWKEMNSFKKDA--WAALIDEHRSAG-ESLKVLDIGTGPGFFAMLL 64

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
           +  GH V   D +  M+  A    +  G   ++QF    +  V    E   DLI+   + 
Sbjct: 65  SGMGHTVTAIDCTENMLVEAGYNVQKVGF--HVQFYKMDSH-VLDFPEGTFDLIVCRNLT 121

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMV-----AGNFDYVQAGMPKKKK 177
             + DP    +    VL+PGG L +   N H  L    +            Q G+P    
Sbjct: 122 WTLRDPVQAYREWHRVLKPGGKLMVFDANWHLRLFDPEMDRLYREDKERARQMGIPDSHD 181

Query: 178 RTLSPDYPRDPAQVYL 193
           ++   +  +   Q+YL
Sbjct: 182 QSNMEESDKIARQLYL 197


>UniRef50_Q46D00 UbiE/COQ5 methyltransferase n=2 Tax=Methanosarcina
           RepID=Q46D00_METBF
          Length = 253

 Score =  123 bits (309), Expect = 6e-27,   Method: Composition-based stats.
 Identities = 47/210 (22%), Positives = 88/210 (41%), Gaps = 19/210 (9%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
           R +D  +E +        K ++ +   W+++ + L  + P +L+VLD G G  +  +  A
Sbjct: 14  RIWDVSSETYDSYEGHGIKSEVERE-AWKNVFKNL--LPPGRLKVLDVGCGTCEIGLLFA 70

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
           E GH V   DLS +M+ +A+  A  +G      F    A+          D+++   +L 
Sbjct: 71  EMGHHVTGLDLSKKMLAKARDKASRRGFDS--VFKKGDAE-APPFKAGSFDVVVNRHLLW 127

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMF--YNAHGLLMHNMVAGNFDY----VQAGMPKKKK 177
            +  P + +Q    VL  GG L ++   +N  G +  N      D+    V+   P+K  
Sbjct: 128 TLPHPDTAVQNWKKVLVGGGKLIVIDGIWN-DGSIETNARRFVSDFLTLLVERRNPRKGH 186

Query: 178 RT------LSPDYPRDPAQVYLWLEEAGWQ 201
            +      L       P ++  +   AG++
Sbjct: 187 YSREVDSELPNKQGVPPEKMLEYFRAAGFK 216


>UniRef50_A7I8W9 Methyltransferase type 11 n=3 Tax=Methanomicrobiales
           RepID=A7I8W9_METB6
          Length = 243

 Score =  123 bits (309), Expect = 6e-27,   Method: Composition-based stats.
 Identities = 44/198 (22%), Positives = 79/198 (39%), Gaps = 16/198 (8%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
           +++D+IAE +  + Y   +G+         + R + E  P+   +LD G G G    K  
Sbjct: 11  QHYDEIAEVYDLH-YDHPRGRTYHT----RISRHVMEALPRGGALLDIGCGTGLFVEKYL 65

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
             G   +  DLS  MI+RA++     G      F     + +    +   D +    V  
Sbjct: 66  HHGGSAVGIDLSRNMIERARRRCSCCG------FTLGTGESLPFR-DNSFDAVASLLVFS 118

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMH-NMVAGNFDYVQAGMPKKKKRTLSP 182
           +V DP S+L   + V+RPGG +S+       L     ++    + ++  +P    +    
Sbjct: 119 YVRDPESMLNEAYRVMRPGGAISICTLGKKLLTSGIPVLYKVSEKIR--IPHVVMKDFGE 176

Query: 183 DYPRDPAQVYLWLEEAGW 200
            Y  D   +      AG+
Sbjct: 177 HY-YDEEDMRALFSRAGF 193


>UniRef50_C6D045 Methyltransferase type 11 n=24 Tax=Bacillales RepID=C6D045_PAESJ
          Length = 241

 Score =  123 bits (309), Expect = 6e-27,   Method: Composition-based stats.
 Identities = 40/152 (26%), Positives = 64/152 (42%), Gaps = 14/152 (9%)

Query: 4   RNFDDIAEKFSRNI---YGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           + FD +A  + +++    G      R A++       L       + VLDAG   G    
Sbjct: 7   KAFDQLAIAYEQSVDHSSGHNAYYERPAMMK------LLPDDMSGMVVLDAGCAAGWYTS 60

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
           + AERG QV   DLS +M+   ++      V D    + C         E   DLI+   
Sbjct: 61  QFAERGAQVTAIDLSPEMVAACRRR-----VGDKANVLVCELGQTLPFEEESFDLIVSSL 115

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNA 152
            L ++ D  SV + +  VL+PGG+L    ++ 
Sbjct: 116 TLHYIEDWGSVFREMRRVLKPGGMLQFSVHHP 147


>UniRef50_C7MMN1 Methylase involved in ubiquinone/menaquinone biosynthesis n=1
           Tax=Cryptobacterium curtum DSM 15641 RepID=C7MMN1_CRYCD
          Length = 263

 Score =  123 bits (308), Expect = 7e-27,   Method: Composition-based stats.
 Identities = 38/148 (25%), Positives = 61/148 (41%), Gaps = 6/148 (4%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
           D  +D+ +  +S  I      ++     W  L   +   G + LRVLD G G G  +I  
Sbjct: 12  DAYWDERSSSYSETIQRELTTEIYHH-WWSVLADTIPGFGKRSLRVLDIGCGPGFFSILC 70

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSD----NMQFIHCAAQDVASHLETPVDLILF 118
           A+ G  V   D S +M+  A+Q     G++      ++F    A+      +   D+I+ 
Sbjct: 71  AQAGCSVDALDCSVKMLAHARQNLFHAGLNTADNVQVRFHQGDAR-FLPFDDGVFDVIVT 129

Query: 119 HAVLEWVADPRSVLQTLWSVLRPGGVLS 146
             V   + DP    +    VL PGG L 
Sbjct: 130 RNVTWNLEDPLGAYREWQRVLIPGGRLI 157


>UniRef50_D0NUY8 3-demethylubiquinone-9 3-methyltransferase, putative n=1
           Tax=Phytophthora infestans T30-4 RepID=D0NUY8_PHYIN
          Length = 252

 Score =  122 bits (307), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 39/170 (22%), Positives = 72/170 (42%), Gaps = 5/170 (2%)

Query: 39  AEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFI 98
             M  + LRV D G G G  +  +   G  ++  D     I  AK+ A     ++ + + 
Sbjct: 58  DPMPLRGLRVADVGCGGGILSEALCRIGGTMVSADPGEDNIAAAKKHAAMSRHTNTIDYR 117

Query: 99  HCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMH 158
            C + D+    E   D++    V+E V+D  + L +L  +++PGG+L L   N    L  
Sbjct: 118 QCTSDDLVVQGE-QFDVVCSLEVIEHVSDVSAFLHSLTPLVKPGGLLFLSSINRTA-LSA 175

Query: 159 NMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
            +  G  +YV   +P         +    P ++   L + G+ +   +G+
Sbjct: 176 ALAIGAAEYVMRIVPPGTHDW---NKFVRPDEIETELRKNGFTVKDVSGI 222


>UniRef50_C4G5R9 Putative uncharacterized protein n=1 Tax=Abiotrophia defectiva ATCC
           49176 RepID=C4G5R9_ABIDE
          Length = 265

 Score =  122 bits (307), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 45/262 (17%), Positives = 97/262 (37%), Gaps = 22/262 (8%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           FD+      + +  + +GQL   I    +D+          ++L+ G G G+ +I++A+ 
Sbjct: 15  FDE-----DKRLTASRQGQLEYFITMNYVDKY----TKPGDKILEIGAGTGRYSIELAKN 65

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV 125
           G+ V   +L    ++  K+ AE     +N+      A ++ S  +   D+ L    +  +
Sbjct: 66  GYDVTAVELVESNLEVLKKNAEGL---ENISAFQGDALNLGSFDDNTFDVTLVFGPMYHL 122

Query: 126 ---ADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFD--YVQAGMPKKKKRTL 180
               D    L     V +P GV+ + F + H ++M N ++ NF   +        K +  
Sbjct: 123 YEEKDRHKALDEAIRVTKPDGVILVAFLSVHAIMMSNYLSVNFKEGFTANFDEDYKVKHF 182

Query: 181 SPDYPR--DPAQVYLWLEEAGWQIMGKTGVRVFHDYL---REKHQQRDCYEALLELETRY 235
           +       D A+     E    + +         +      +     + +   L  +   
Sbjct: 183 TEQAFTGFDIAEFEEMFEAKPVEYITTVAADSILEIAERNPDFKMSDEDFGLFLNYQMNI 242

Query: 236 CRQEPYITLGRYIHVTARKPQS 257
           C +   + L  ++    RK + 
Sbjct: 243 CEKREMLGLSSHLLYICRKIRC 264


>UniRef50_Q02BK2 Methyltransferase type 12 n=1 Tax=Candidatus Solibacter usitatus
           Ellin6076 RepID=Q02BK2_SOLUE
          Length = 281

 Score =  122 bits (306), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 46/208 (22%), Positives = 88/208 (42%), Gaps = 9/208 (4%)

Query: 44  QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQ 103
           +  +VL+ G G G   I  A  G QV   DL+ + ++ A+Q A+  G+ D ++FI   A+
Sbjct: 63  RGKKVLEIGCGIGTDTINFARHGAQVTAVDLTEKSLEVARQRAKVFGLEDRIRFIQANAE 122

Query: 104 DVASHLE-TPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVA 162
            ++  +     DLI    V+     P +VL+ L   + P   + +M YN     +  ++ 
Sbjct: 123 KLSESVPLEQYDLIYSFGVIHHTPHPENVLEQLRKYVSPQSTVKIMVYNRWSWKVLWILL 182

Query: 163 GNFDYVQAGMPKKKKRTLSPDYPRDPAQV-YLWLEEAGWQIMGKTGVRVFHDYLREKHQQ 221
           G   Y +  + K  +        +    V Y +    G +++   G+RV  + + +    
Sbjct: 183 G---YGKGQVWKMNRLIAEYSEAQTGCPVTYSYSRTGGTKLLEAHGLRV-TEVMVDHI-- 236

Query: 222 RDCYEALLELETRYCRQEPYITLGRYIH 249
              YE    ++ RY     +  + R + 
Sbjct: 237 -FAYEISEYVQYRYKMVWYFRWMPRSLF 263


>UniRef50_A9KR97 Methyltransferase type 11 n=1 Tax=Clostridium phytofermentans ISDg
           RepID=A9KR97_CLOPH
          Length = 265

 Score =  122 bits (306), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 39/225 (17%), Positives = 88/225 (39%), Gaps = 11/225 (4%)

Query: 37  VLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQ 96
            + +   +  R+LD G G G+ ++  A +G++V   +L++  I+  ++    +   D ++
Sbjct: 45  YIEKYLKEGDRILDLGAGAGEYSLYFARKGYEVTAVELASANIEAFQKKITGE---DKIE 101

Query: 97  FIHCAAQDVASHLETPVDLILFHAVLEWV---ADPRSVLQTLWSVLRPGGVLSLMFYNAH 153
            IH  A D++   E   D++L    L  +    D +  +     VL+P G +   F   +
Sbjct: 102 LIHGNALDLSCFAEDSFDVVLLFGPLYHLSKEEDRQKCITEAKRVLKPTGTIFFAFI-LN 160

Query: 154 GLLMHNMVAGNFDYVQAGMPKKKKRTLS--PDYPRDPAQVYLWLEEAGWQIMGKTGVRVF 211
            +++   +    D+        +   +   P       Q    L+ AG QI+ +      
Sbjct: 161 DMVILTELYYRQDFFLENSYDHETFKVEDFPFVFFTVDQTREMLQAAGIQILKEIASDGV 220

Query: 212 HDYLREKH--QQRDCYEALLELETRYCRQEPYITLGRYIHVTARK 254
            + L +K      + Y+  +      C +   +    ++    +K
Sbjct: 221 SELLEDKINAMDEESYKQYVRYHLYCCEKPEMLGRSNHLLTIGKK 265


>UniRef50_C8VZ57 Methyltransferase type 11 n=1 Tax=Desulfotomaculum acetoxidans DSM
           771 RepID=C8VZ57_DESAS
          Length = 240

 Score =  122 bits (306), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 50/206 (24%), Positives = 82/206 (39%), Gaps = 16/206 (7%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIK 61
            +  FDDIA K+         G+L   +  +   +   ++      VLD G G G   I 
Sbjct: 6   SNPTFDDIAAKYD-LWAKLPLGKLCAKLENEAFFKAYGDIAGSDP-VLDIGCGTGNYIIN 63

Query: 62  MAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
           +A  G  V   D S  M+  A+Q    +G   ++  +H  A+++    E     ++    
Sbjct: 64  LAGCGLDVTGLDASENMLAVARQKLTKQGFQASL--VHSLAENIP-FKEHSFKTVICSLA 120

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHG-LLMHNMVAGNFDYVQAGMPKKKKRTL 180
           LE++  P  V+Q ++ VL+P G   L F N      M+ M+ G   YVQ  +        
Sbjct: 121 LEFMGRPEKVVQEIFRVLQPSGQFILAFLNFWSPWNMYRMLKG---YVQPTIY------- 170

Query: 181 SPDYPRDPAQVYLWLEEAGWQIMGKT 206
           +         V   L+EAG+      
Sbjct: 171 NNANFMSRYYVNKVLKEAGFTDFSYY 196


>UniRef50_B8HW44 Methyltransferase type 11 n=2 Tax=Bacteria RepID=B8HW44_CYAP4
          Length = 272

 Score =  122 bits (306), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 45/181 (24%), Positives = 80/181 (44%), Gaps = 12/181 (6%)

Query: 47  RVLDAGGGEGQTAIKMAERGH---QVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQ 103
           RVLD   G G +AI  A       QV+  DL+  ++  A+Q A+ +G+ +N++F     +
Sbjct: 48  RVLDVCCGTGASAIPAAVCVGPTGQVLGIDLAESLLQLARQKAQQQGL-ENIEFQCGDFE 106

Query: 104 DVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAG 163
           ++        D I+    + +V D  + +Q LW ++R GG L++  +        N +  
Sbjct: 107 NLG-LPNESFDAIICVFGIFFVPDMLAAMQELWRMVRSGGKLAITSWGKQVFEPANQMF- 164

Query: 164 NFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRD 223
            +D V+A  P   ++    D   +PA +   LE  G      T V VF +    +    +
Sbjct: 165 -WDAVEAERPDLVRKFTPWDRINEPALLQALLEAGG-----ATQVEVFTEITTYELAAPE 218

Query: 224 C 224
            
Sbjct: 219 D 219


>UniRef50_Q7VRW8 3-demethylubiquinone-9 3-methyltransferase n=2 Tax=Candidatus
           Blochmannia RepID=Q7VRW8_BLOFL
          Length = 245

 Score =  121 bits (305), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 40/164 (24%), Positives = 76/164 (46%), Gaps = 6/164 (3%)

Query: 45  KLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQD 104
           K +VLD G G G  + K+A+ G +V+  D+S   +  AK  A +K ++  + +I   A++
Sbjct: 61  KKKVLDIGCGGGLLSEKLAQAGAKVVGLDISPNSLIIAKAHALSKNLT--INYILETAEE 118

Query: 105 VASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGN 164
            A       DLI    +LE V DP S++    S+++ GG +     N        ++ G 
Sbjct: 119 HALKYIKYYDLIACMELLEHVPDPLSIIHACSSMVKVGGSVFFSTLNRTMKAWLLVIIGA 178

Query: 165 FDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
            +Y+   +P       + +    P+++  W++    +    TG+
Sbjct: 179 -EYLIHLLPIGTH---TFNKFITPSELLNWIDTTKLEANNITGI 218


>UniRef50_D1JD56 Putative uncharacterized protein n=1 Tax=uncultured archaeon
           RepID=D1JD56_9ARCH
          Length = 267

 Score =  121 bits (305), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 40/181 (22%), Positives = 75/181 (41%), Gaps = 17/181 (9%)

Query: 37  VLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQ 96
           +  E+   KL +LDAG G G  A+ +A  GH V+  DLS  M+ RA + A+ +G+  N+ 
Sbjct: 47  LSDEIVGNKLSILDAGTGTGFLALSLAGMGHDVVGIDLSEGMLSRAIKKAKERGL--NLD 104

Query: 97  FIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSL--------- 147
                 + +    +   D+++   VL  +  P   ++    VL+PGG +           
Sbjct: 105 LRMGDVESL-DFDDKSFDVVVTRWVLWTLIHPDKAIEEWLRVLKPGGYVYAFGSKEPGRK 163

Query: 148 ----MFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRD-PAQVYLWLEEAGWQI 202
                F     +    ++     + ++   K+ K  L   Y +  P +     ++AG   
Sbjct: 164 GRWRWFKANFAMAAITVLERRNAWARSDYDKEVKENLPLHYDKTGPREKVKLFKKAGLND 223

Query: 203 M 203
           +
Sbjct: 224 V 224


>UniRef50_UPI000051ABE2 PREDICTED: similar to coenzyme Q3 homolog, methyltransferase n=2
           Tax=Apocrita RepID=UPI000051ABE2
          Length = 286

 Score =  121 bits (305), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 38/181 (20%), Positives = 73/181 (40%), Gaps = 7/181 (3%)

Query: 39  AEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAA-EAKGVSDNMQF 97
             +  + +++LD G G G  +  +A  G  V   D S+++I  AKQ A     +   + +
Sbjct: 90  PYLPLEGIKILDVGCGGGLLSESLARIGADVTGIDASSELITAAKQHAVLDASLDGKLNY 149

Query: 98  IHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLM 157
                +D A + +   + ++   V+E V +    L+   S L+PGG + L   N      
Sbjct: 150 FQTIIEDFALNNKEVYNAVVASEVIEHVNNKELFLKCCISSLKPGGSIFLTTINKTLPSW 209

Query: 158 HNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLRE 217
                G     +  +    K T   +    P ++   LE  G +     G+  F++ L+ 
Sbjct: 210 ----LGGIIAAERILKVVPKGTHDWNKFVTPTEMQSLLETYGCKTKLIHGM--FYNILKN 263

Query: 218 K 218
           +
Sbjct: 264 E 264


>UniRef50_B0C971 Methyltransferase, putative n=1 Tax=Acaryochloris marina MBIC11017
           RepID=B0C971_ACAM1
          Length = 284

 Score =  121 bits (305), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 43/208 (20%), Positives = 81/208 (38%), Gaps = 17/208 (8%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMG-PQKLRVLDAGGGEGQTAIK 61
           D+    +A+ + R      +GQ    I     DR+L          VLD G G G  AI 
Sbjct: 7   DKFKQGVADFYDRRSRSYDQGQWHPQI----CDRLLEYARIGAGQTVLDIGTGTGYLAIA 62

Query: 62  MAERGH---QVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILF 118
            A+R      V   D+S  M+ +A++  +  G+S N+      A+ +  +     D+IL 
Sbjct: 63  SAQRVGDQGHVTGVDISPGMLQQAQRKIQRLGLS-NVVVQRADAEAL-DYPSHHFDVILC 120

Query: 119 HAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKR 178
                W+ D  + L+  + +L+P G +++        +   ++       + G+  +   
Sbjct: 121 AHTFPWMTDKAATLRLWYQLLKPRGRIAVHTPADTAYIGAVVLRRVL--AEYGLELEPSN 178

Query: 179 TLSPDYPRDPAQVYLWLEEAGWQIMGKT 206
            L         Q     E+AG++ +   
Sbjct: 179 RLG-----SIEQCRQLFEKAGFEAVEIY 201


>UniRef50_Q9K8W5 BH2887 protein n=1 Tax=Bacillus halodurans RepID=Q9K8W5_BACHD
          Length = 261

 Score =  121 bits (305), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 41/188 (21%), Positives = 77/188 (40%), Gaps = 14/188 (7%)

Query: 18  YGTTKGQLRQAILWQDLDRVLAEMGPQKLR-VLDAGGGEGQTAIKMAERGHQVILCDLSA 76
           +       R   +    + ++  + P++   VLD G G G    ++ + G +VI  D+S 
Sbjct: 13  WNAKLYDERHRFVSAYGEDLIQWLAPKEGECVLDLGCGTGDLTEQIHQLGSRVIGVDVSE 72

Query: 77  QMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLW 136
            MI++AK      G   ++ F    A D++       D I  +AVL W+ D    L  ++
Sbjct: 73  SMIEQAK------GKFPHLDFQVAEATDLSFS--EKFDAIFSNAVLHWIKDAEEALTVIY 124

Query: 137 SVLRPGGVLSLMFYNAHGLL-MHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWL 195
             L+PGG     F     +  + N +A       +   K++     P +     Q    +
Sbjct: 125 RSLKPGGRFVAEFGGKGNVETIVNTLADTMSQADSRWSKEE----LPWFFPSIGQYTSLM 180

Query: 196 EEAGWQIM 203
           E+ G+++ 
Sbjct: 181 EQVGFRVT 188


>UniRef50_UPI0000E495F1 PREDICTED: hypothetical protein n=2 Tax=Strongylocentrotus
           purpuratus RepID=UPI0000E495F1
          Length = 351

 Score =  121 bits (304), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 34/165 (20%), Positives = 65/165 (39%), Gaps = 5/165 (3%)

Query: 45  KLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKG-VSDNMQFIHCAAQ 103
              ++D G G G  A  +A  G  VI  D + + I+ A+        +  N+++I   A+
Sbjct: 155 GATIVDVGCGGGILAEPLARLGATVIGVDATPENIEVAQHHVSHDPTIRGNVKYICGTAE 214

Query: 104 DVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAG 163
           D+    +   D ++   VLE V+   + ++T   +++PGG +     N   L     +  
Sbjct: 215 DLVCTEDEAFDALVCSEVLEHVSHKENFIKTCAELVKPGGSIFFTSVNQTWLSYALGIVM 274

Query: 164 NFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
             + V   +P         +    P  +   LEE    +    G+
Sbjct: 275 A-EKVLGLVPDGTHDW---NKFISPGYIQRVLEENDCSVRLTHGM 315


>UniRef50_Q7Q8W1 AGAP010535-PA n=1 Tax=Anopheles gambiae RepID=Q7Q8W1_ANOGA
          Length = 266

 Score =  121 bits (304), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 37/164 (22%), Positives = 69/164 (42%), Gaps = 5/164 (3%)

Query: 44  QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAK-GVSDNMQFIHCAA 102
           + L +LD G G G  A  +A+    V+  D +  +I+ AK  AEA+  + D   +   + 
Sbjct: 79  KGLNILDVGCGGGIYAEALAKLHANVVGIDPARHLIEVAKAHAEAQSDIKDRCHYYEQSM 138

Query: 103 QDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVA 162
           ++         D+++    +E V D  S+L+ +  VL+PGG + +  +N         V 
Sbjct: 139 EEHWQGAANKYDVVVLSETIEHVVDKSSLLKHVAEVLKPGGSVFISTWNKTSWSWLLAVV 198

Query: 163 GNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKT 206
              + +   +PK        D    P +    LE  G + + + 
Sbjct: 199 -VLENIMKRLPKGSHDY---DKFVSPEETEAILEAYGCRTIEQR 238


>UniRef50_Q8NMH1 SAM-dependent methyltransferases n=2 Tax=Corynebacterium glutamicum
           RepID=Q8NMH1_CORGL
          Length = 251

 Score =  121 bits (304), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 36/153 (23%), Positives = 68/153 (44%), Gaps = 3/153 (1%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
           +  +   AE +  N   + + Q  + I  +   + L  +  + ++VLD G G G     +
Sbjct: 11  NNYWSGRAEAYHLNQTQSERAQFERPIWEKVWSKALPIVSEEAVKVLDLGCGAGYVTHLL 70

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQ--FIHCAAQDVASHLETPVDLILFHA 120
           ++ G++ I  D S +MI++A Q    +  +      F    A D     E   D I    
Sbjct: 71  SDCGYETIGVDGSEEMINQATQENGLRRSTGRATAIFQVGDAHD-PEFREGSFDAITSRY 129

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAH 153
           VL  + DP++ +    S+L+PGGV++ +    +
Sbjct: 130 VLWTLLDPQAAINRWVSLLKPGGVIACVDAAWY 162


>UniRef50_C6PBK3 Methyltransferase type 11 n=1 Tax=Thermoanaerobacterium
           thermosaccharolyticum DSM 571 RepID=C6PBK3_CLOTS
          Length = 211

 Score =  121 bits (304), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 42/206 (20%), Positives = 88/206 (42%), Gaps = 22/206 (10%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMG----PQKLRVLDAGGGEGQTAI 60
            FD IA ++          ++R+     D+  +  E         L V D G G G  A+
Sbjct: 6   YFDSIAGEWD---------EIRKKYFDDDIRNIAIERSNIKNKGGLIVADIGTGSGFMAL 56

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
           ++++   +V+  D+S +M+  AKQ AE  G+ +N+ F+  + + +   ++  +D++  + 
Sbjct: 57  ELSKYAREVVGIDVSDEMLKYAKQTAENAGI-NNIIFLKGSMEQIP-IIDDSIDVVFSNM 114

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
           VL  V +P   +  +  +L+PGG+L +     H           +D       +  ++ L
Sbjct: 115 VLHHVENPFKGIMEIHRILKPGGMLIITDVMKHSSEWAR--FEMYDRWLGFNLEDIEKWL 172

Query: 181 SPDYPRDPAQVYLWLEEAGWQIMGKT 206
                ++       ++E G     K+
Sbjct: 173 IHSNFKEI-----LVKETGLYATAKS 193


>UniRef50_Q67LB5 Conserved domain protein n=1 Tax=Symbiobacterium thermophilum
           RepID=Q67LB5_SYMTH
          Length = 268

 Score =  121 bits (303), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 47/202 (23%), Positives = 82/202 (40%), Gaps = 17/202 (8%)

Query: 8   DIAEKFSRN--IYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEG----QTAIK 61
            +A  +SR   +Y    G    A + + L  V     P    +LD G G G    + A  
Sbjct: 7   RLAMGYSRTSALYDLLAGHGYLAAIRRLLPLVRVRHRPA---ILDVGCGTGLNLFEAARW 63

Query: 62  MAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
            A  G  ++  DLS  M+  A   A   G+   +  +   A+ +    +   DL+L ++V
Sbjct: 64  FAPTGP-LVGIDLSPGMVAVAAAKARQLGIPATI--LLGDAERLP-LPDASFDLVLCNSV 119

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLS 181
             W  D  + ++ +  VL+PGG L+L+   A G     ++    D V   +    +    
Sbjct: 120 FHWFRDRPAAMREMARVLKPGGQLALITATAPGFREWFLL---IDAVIRVVLGPDRAPPI 176

Query: 182 PDYPRDPAQVYLWLEEAGWQIM 203
           P+ P    +V   ++ AG  + 
Sbjct: 177 PELP-TAEEVAALMQAAGLAVE 197


>UniRef50_Q5PAV2 3-demethylubiquinone-9 3-methyltransferase n=1 Tax=Anaplasma
           marginale str. St. Maries RepID=Q5PAV2_ANAMM
          Length = 225

 Score =  121 bits (303), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 40/167 (23%), Positives = 65/167 (38%), Gaps = 8/167 (4%)

Query: 49  LDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASH 108
           LD G G G  A  M   G  V   D S   I+ A   A   G+  ++ +         ++
Sbjct: 40  LDIGCGGGIFAESMVRLGFSVTGVDPSQASIEAASTHARVAGL--DIHYHCAHLDQFCAN 97

Query: 109 LETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYV 168
                D++    V+E V D  S L+    +L+ GG+L L   N     M   +    +YV
Sbjct: 98  HPEVYDVVTLMEVVEHVTDLESCLENACRLLKRGGMLFLSTLNRTLKSMILAIVAA-EYV 156

Query: 169 QAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV--RVFHD 213
              +P+      S +    P++V   L   G  +   +G+  RV  +
Sbjct: 157 LRWVPRGTH---SWNKFVRPSEVCSMLRARGVIVQNISGMKYRVLQN 200


>UniRef50_A9G9E0 Putative uncharacterized protein n=1 Tax=Sorangium cellulosum 'So
           ce 56' RepID=A9G9E0_SORC5
          Length = 387

 Score =  121 bits (303), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 50/204 (24%), Positives = 81/204 (39%), Gaps = 20/204 (9%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQ-KLRVLDAGGGEGQTAIKMAE 64
           F ++ + F R         L        +D ++  + P  + R LD G G G+   +M  
Sbjct: 178 FHELVDFFDRMQAEGPYATL--------IDELVTLVDPGVEERCLDLGCGTGRLTREMGR 229

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
           R H+ I  D +A M++RA Q A+A G+ DN+ F    A  +    +   D++    +L  
Sbjct: 230 RCHESIGIDATAAMVERAAQRAKALGL-DNVTFREALATRLP-FPDASFDVVTASNLLLH 287

Query: 125 VADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSP-- 182
           + +P  VL     VLRPGG L+L+        M       +       P      L+   
Sbjct: 288 LPEPGPVLAEAVRVLRPGGRLALLEP---AATMSRAAMAGYLRGHRYNPSTAHAMLAWAD 344

Query: 183 ----DYPRDPAQVYLWLEEAGWQI 202
                Y     ++   L  AG Q+
Sbjct: 345 AAEVTYRHTEDKLGGELSGAGLQV 368


>UniRef50_A6C296 UbiE/COQ5 methyltransferase n=2 Tax=Planctomycetaceae
           RepID=A6C296_9PLAN
          Length = 256

 Score =  121 bits (303), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 56/231 (24%), Positives = 95/231 (41%), Gaps = 26/231 (11%)

Query: 11  EKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVI 70
           E+F +  +G    +      W D+ R     G    ++LD G G G  A+  AE GH + 
Sbjct: 26  ERFIKGEFGFAASRS----AWLDVLRKTVP-GEIPCKILDMGTGPGTIALLWAELGHAIT 80

Query: 71  LCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRS 130
             D SA MI   ++AA+ +G++  + F+    +      E   D+I   AVL  +  P  
Sbjct: 81  GVDFSATMISAGREAAKERGLT--VDFVEADVE-APPFPENTFDIISSRAVLFTLPHPGY 137

Query: 131 VLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQ 190
            +     +L+PGGVL L+  N                     P+K KR   P    +P +
Sbjct: 138 AVAQWIRLLKPGGVLVLIGENN-----------------PTDPEKLKRQHRPAPGWEPDE 180

Query: 191 VYL-WLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP 240
            Y   LE+  ++      VRV  +    ++ Q    +++L     + ++ P
Sbjct: 181 AYRNALEQLPFRSHTDGMVRVVMEAAGLRNIQNLPMQSVLAAREEHEQENP 231


>UniRef50_D1VDC2 Methyltransferase type 11 n=1 Tax=Frankia sp. EuI1c
           RepID=D1VDC2_9ACTO
          Length = 283

 Score =  121 bits (303), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 42/196 (21%), Positives = 74/196 (37%), Gaps = 10/196 (5%)

Query: 17  IYGTTKGQLRQAILWQDLDRVLAEMG--PQKLRVLDAGGGEGQTAIKMA-ERGHQVILCD 73
            Y       R +   + ++R L +        RVLDAG G G  A  +A + G  +   D
Sbjct: 36  WYEAGDSGWRFSPAMRRMERQLGQRLGLEADSRVLDAGCGMGDVARTLAADFGLDITGID 95

Query: 74  LSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQ 133
           +    +  A++ +E  G+++  +FI C   D++   +   D +         AD    L 
Sbjct: 96  ILDFNLVEARRRSERAGLANRTRFIECDYHDLSRFEDGEFDGVYTMETFVHAADAERALA 155

Query: 134 TLWSVLRPGGVLSLMFYNAH-GLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVY 192
               VLRPGG L +  Y+      +       FD V       +   +   +  +   + 
Sbjct: 156 EFHRVLRPGGRLVMFEYSRTPNECLLPAARAAFDAVC------ELGAMPAWHRLNHGDLE 209

Query: 193 LWLEEAGWQIMGKTGV 208
             LE A +++     V
Sbjct: 210 NLLESASFKVESVEDV 225


>UniRef50_C7MH99 Methylase involved in ubiquinone/menaquinone biosynthesis n=1
           Tax=Brachybacterium faecium DSM 4810 RepID=C7MH99_BRAFD
          Length = 155

 Score =  121 bits (303), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 42/146 (28%), Positives = 63/146 (43%), Gaps = 5/146 (3%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLR-VLDAGGGEGQTAI 60
           QDR +++   +++         +L  A       R+ A+  P   R VLD G G G  A+
Sbjct: 9   QDR-WNEYWTRYAFEYDEHQLSRLAHADERATWSRIWADALPIGTRSVLDVGTGTGNVAL 67

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
           ++A  G++V   DLS  M++RA+      G      F+   A           D I+   
Sbjct: 68  QLAADGYEVTGIDLSEGMLERARAKC--AGHPAPPTFLRGDAVQ-PPFPPGSFDAIVSRY 124

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLS 146
           VL  + D  S LQ    +LRPGG L 
Sbjct: 125 VLWTLRDAASALQRWHELLRPGGTLV 150


>UniRef50_A1HPJ4 Methyltransferase type 11 n=1 Tax=Thermosinus carboxydivorans Nor1
           RepID=A1HPJ4_9FIRM
          Length = 229

 Score =  121 bits (303), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 38/205 (18%), Positives = 72/205 (35%), Gaps = 19/205 (9%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
             F ++A K+    + T  GQ       + +  +      Q + V D G G G    +  
Sbjct: 2   NYFQELAAKYD-AWFQTPHGQYVYRYEREMIFDLAE--VQQDMYVADVGCGTGIYTNEFC 58

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
             G +V+  D+S +M+  A +  +  G  + + F+   A  +    +   D+++    +E
Sbjct: 59  AAGARVVGIDISPEMLAIAAEKNKTWG--NRVSFVTADAAALP-FPDNAFDMVVSITAME 115

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGL-LMHNMVAGNFDYVQAGMPKKKKRTLSP 182
           +  +PR  L  +  +LRPGG + +       L  M   +   F           +   S 
Sbjct: 116 FFEEPRRCLHEMHRILRPGGRMIVATLGNWSLWSMQRRLKTLF----------TRTIFSH 165

Query: 183 DYPRDPAQVYLWLEEAGWQIMGKTG 207
                   +   L      I    G
Sbjct: 166 TRFYSIRDIARLLN--PITISEWRG 188


>UniRef50_C9L9K1 SmtA protein n=1 Tax=Blautia hansenii DSM 20583 RepID=C9L9K1_RUMHA
          Length = 260

 Score =  121 bits (303), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 40/177 (22%), Positives = 73/177 (41%), Gaps = 19/177 (10%)

Query: 44  QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQ 103
            K+++LD G G G  +I +++RG+Q+   D S  M++ AK  A    ++DN++F+   AQ
Sbjct: 57  SKMKILDIGTGPGFYSIILSKRGYQMTAVDSSEGMLEEAKHNAGE--LADNIEFLCMDAQ 114

Query: 104 DVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLM------ 157
            +    +   D+I+   +   +  P    +    VL+P G+L     N +  L       
Sbjct: 115 KL-DFEDNTFDVIVTRNLTWNLPKPAEAYKEWKRVLKPNGILLNFDANWYSYLFDEEKEK 173

Query: 158 ----------HNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMG 204
                        V  +  Y +  M +   R L     + P      L E G++ + 
Sbjct: 174 EYQQDRLNTVKAGVEDHGAYEEGDMMEDISRCLPMGKVKRPQWDLAVLLECGFKTVS 230


>UniRef50_C5KJI6 3-demethylubiquinone-9 3-methyltransferase, putative n=5
           Tax=Perkinsus marinus ATCC 50983 RepID=C5KJI6_9ALVE
          Length = 312

 Score =  121 bits (303), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 39/170 (22%), Positives = 69/170 (40%), Gaps = 14/170 (8%)

Query: 43  PQKLRVLDAGGGEGQTAIKMA-ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCA 101
           P K R LD G G G     MA   G+ +   D+S   + +A++         N+ +   +
Sbjct: 86  PSKGRYLDVGCGGGLLTEDMASTYGYNITGIDISEASLQQAREHGRH---IPNLHYQVGS 142

Query: 102 AQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAH--GLLMHN 159
           A D+    +   D ++   VL+ + D R  +Q ++ VL+PGGV+     + +    L+  
Sbjct: 143 AYDIP-FPDNSFDGVIISEVLDHLMDLRKAIQEIYRVLKPGGVVVFDTISRNFKSYLLVW 201

Query: 160 MVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQI-MGKTGV 208
           ++A     V          T        P ++   L E G+ +     GV
Sbjct: 202 LIAQEILQVMYN------DTHDWRLFITPEEMERLLSETGFVVGECAFGV 245


>UniRef50_B3E0R3 Methylase involved in ubiquinone/menaquinone biosynthesis n=1
           Tax=Methylacidiphilum infernorum V4 RepID=B3E0R3_METI4
          Length = 287

 Score =  121 bits (303), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 51/231 (22%), Positives = 98/231 (42%), Gaps = 26/231 (11%)

Query: 4   RNFD--DIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIK 61
            +FD   +A ++ R +      Q R+ +    + R          RVLD G G G+ A  
Sbjct: 26  YSFDSLQLAAEYDR-LSDPQFNQGRELVSLLKIKRA--------DRVLDIGCGTGRLAAY 76

Query: 62  MA----ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLIL 117
           +A    + G +VI  D S   I  A++  ++     N+ F     ++++   +   D++ 
Sbjct: 77  VAGITGKEG-KVIGIDPSPFRIAIARRREKS-----NLLFKVAGTEELSLFEDNSFDVVY 130

Query: 118 FHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAH-GLLMHNMVAGNFDYVQAGMPKKK 176
            ++V  W+ D    +  ++ VL+PGG L +     H   L+ +++  +   V   +PK+ 
Sbjct: 131 LNSVFHWIGDRAQAMVEIYRVLKPGGKLGIAMGAKHQDSLLVSILRRSAQSVLGYIPKEF 190

Query: 177 KRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEA 227
                 +Y R+  +      E+G++I      R + D  R   +    YEA
Sbjct: 191 ALN---EYQREADEALELSRESGFKIQEIKT-RHYVDLFRSGEECIRFYEA 237


>UniRef50_B8GH63 Methyltransferase type 11 n=1 Tax=Methanosphaerula palustris E1-9c
           RepID=B8GH63_METPE
          Length = 270

 Score =  120 bits (302), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 41/203 (20%), Positives = 84/203 (41%), Gaps = 16/203 (7%)

Query: 8   DIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKL-RVLDAGGGEGQTAIKMAERG 66
           ++AE++ +   G           + +   ++A +G +K   VLD G G G+   ++A+  
Sbjct: 12  ELAERYDQVSEGQ----------YNNGLTLIANLGVKKGQTVLDIGCGTGRLTSRVAKIV 61

Query: 67  H---QVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
               QVI  D S + I+ A++       S N+      A  +        D++  + V  
Sbjct: 62  GDTGQVIGIDPSKERIEIARRNVPDSPRS-NISLEIGDANSLYHFQNNSFDIVYLNIVFH 120

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPD 183
           W+ + +  L  ++ VL+PGG+L +   N        ++A      Q    +  ++  +  
Sbjct: 121 WIDNKKDALSQIYRVLKPGGLLGITTGNRDQPHTVTIIADRI-LTQPKYARSAQQGRASS 179

Query: 184 YPRDPAQVYLWLEEAGWQIMGKT 206
            P +  ++   L   G+ I+  T
Sbjct: 180 KPVNVLEMVSLLHATGYSILDIT 202


>UniRef50_C2HDY5 S-adenosylmethionine-dependent methyltransferase n=12
           Tax=Enterococcus faecium RepID=C2HDY5_ENTFC
          Length = 200

 Score =  120 bits (302), Expect = 4e-26,   Method: Composition-based stats.
 Identities = 48/179 (26%), Positives = 85/179 (47%), Gaps = 11/179 (6%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M    FD IA  +      +   Q    I+ ++L   L     QK+ +LD GGG G  ++
Sbjct: 1   MTKNIFDSIANHYD-----SPDRQALAKIIREELTTYLPRDSHQKV-LLDYGGGTGLVSL 54

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
            +AER  ++I+ D S  M+   ++  +A  +  N++ IH  A           D+IL   
Sbjct: 55  PLAERFKELIIADASETMLKMVEEKIQAADLK-NVRTIHADAS--VEFPAIQADVILLSL 111

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRT 179
           VL  + D +++L  L+ +L PGG L ++ ++ +  + H  V   F  +Q  +  + K+T
Sbjct: 112 VLLHIPDTKTILMKLFELLAPGGQLIIVDFDKNEQISHPKVHNGF--IQEELNDRLKKT 168


>UniRef50_B9JTF4 Ubiquinone biosynthesis O-methyltransferase n=1 Tax=Agrobacterium
           vitis S4 RepID=B9JTF4_AGRVS
          Length = 260

 Score =  120 bits (302), Expect = 4e-26,   Method: Composition-based stats.
 Identities = 46/184 (25%), Positives = 76/184 (41%), Gaps = 7/184 (3%)

Query: 25  LRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQ 84
           +R            +      LRVLD G G G  +  +A  G  V+  D SA+ I  A+ 
Sbjct: 53  IRDKACENYQRDPRSNQPLSGLRVLDIGCGGGLLSEPIARMGADVLGADASAKNIGIAQT 112

Query: 85  AAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGV 144
            A   GVS + + +   A    +      D++L   V+E VAD    + T  S++RPGG+
Sbjct: 113 HAAQTGVSVDYRAVTAEA---LAAAGESFDIVLNMEVVEHVADVEYFISTCASMVRPGGI 169

Query: 145 LSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMG 204
           + +   N   L    +  G  +YV   +P+   +    +    P ++   +  AG  +  
Sbjct: 170 MLISTINRT-LKAAALAIGACEYVLRWLPRGTHQY---EKLVRPEELEKPILGAGMNVSE 225

Query: 205 KTGV 208
             GV
Sbjct: 226 TVGV 229


>UniRef50_B2J5L2 Methyltransferase type 11 n=1 Tax=Nostoc punctiforme PCC 73102
           RepID=B2J5L2_NOSP7
          Length = 265

 Score =  120 bits (301), Expect = 5e-26,   Method: Composition-based stats.
 Identities = 42/222 (18%), Positives = 85/222 (38%), Gaps = 26/222 (11%)

Query: 6   FDDIAEKFS---RNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
           +D  A+ +     +   + +      +LW     V        L VLDAG G G  A ++
Sbjct: 18  WDRRAKDWDIPVGDDGDSNRILNSDPVLWSFAGNV------AGLSVLDAGCGTGYLARQL 71

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
             +G  V   D S QMI+ AK  A    +  ++ F   +  ++ S  +   D+I+ + VL
Sbjct: 72  CLKGASVTGIDFSPQMIEIAKFRASQNNL--DIDFHLDSCTELKSLPDEQFDMIVSNYVL 129

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFD------YVQAGMPKKK 176
             + D    ++    VL+P G ++++ ++       N    N D      +  +   + +
Sbjct: 130 MDLLDLEGAIRAFNRVLKPSG-IAILVFSHPCFPQGNSTTVNEDGTVSYSWASSYFERTQ 188

Query: 177 KRTLSPDYPRDP--------AQVYLWLEEAGWQIMGKTGVRV 210
                 ++   P        +  +   + AG+ +      R+
Sbjct: 189 HNDEPWNHFTTPFIWFHRPLSDYWKVFKAAGFSVDEFEEPRI 230


>UniRef50_B5JNH0 Methyltransferase domain family n=1 Tax=Verrucomicrobiae bacterium
           DG1235 RepID=B5JNH0_9BACT
          Length = 263

 Score =  120 bits (301), Expect = 5e-26,   Method: Composition-based stats.
 Identities = 36/115 (31%), Positives = 54/115 (46%), Gaps = 2/115 (1%)

Query: 44  QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQ 103
           +  +VLD   G G  +  +A  G QV   DLS   I+ AK+ A  +G+S N +F+   A+
Sbjct: 63  KGKKVLDYCCGAGGNSRFVAACGAQVTGIDLSDSEIETAKRLANEEGLSKNTEFVVMDAE 122

Query: 104 DVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMH 158
              S      D+I+   VL  V D     + L  VL+PGG L  +    H  ++ 
Sbjct: 123 K-TSFENETFDMIICSGVLHHV-DLDVAYKELNRVLKPGGKLVCIEALGHNPIIR 175


>UniRef50_D1A8N4 Methyltransferase type 11 n=2 Tax=Streptosporangineae
           RepID=D1A8N4_THECD
          Length = 337

 Score =  120 bits (301), Expect = 6e-26,   Method: Composition-based stats.
 Identities = 46/170 (27%), Positives = 76/170 (44%), Gaps = 15/170 (8%)

Query: 35  DRVLAEMGPQK-LRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSD 93
             ++  + PQ   R++D G G G  +  +AERG QV+  D S +MI      A+A     
Sbjct: 20  APLVDLLDPQPDERIIDLGCGTGVFSAAIAERGAQVLGIDGSPEMI------AQAAATYP 73

Query: 94  NMQFIHCAAQDVASHLETPVDLILFHAVLEWV-ADPRSVLQTLWSVLRPGGVLSLMFYNA 152
            + F+   A D  +    P D +  +A L W+  DP +V++ ++  LRPGG   +     
Sbjct: 74  QLSFVVADAHDFTTS--EPYDAVASNAALHWMTRDPDAVIKAVYKALRPGGRF-VAEMGG 130

Query: 153 HGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQI 202
            G     + A    +   G+ + +     P Y   PA+    LE AG+ +
Sbjct: 131 AGNCAELIAAMQTAWRIFGLAEPE----LPWYFPTPAEYASKLEAAGFTV 176


>UniRef50_B8EI29 3-demethylubiquinone-9 3-methyltransferase n=1 Tax=Methylocella
           silvestris BL2 RepID=UBIG_METSB
          Length = 256

 Score =  120 bits (301), Expect = 6e-26,   Method: Composition-based stats.
 Identities = 44/186 (23%), Positives = 74/186 (39%), Gaps = 8/186 (4%)

Query: 39  AEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFI 98
           A    + LR+LDAG G G  A  +A  G +V   D + + I+ A++ AE  G+S  + + 
Sbjct: 67  APRPLEGLRILDAGCGAGLLAEPLARLGARVTAIDPAPRNIEVARRHAEKSGLS--IDYR 124

Query: 99  HCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMH 158
               + ++       D +L   VLE V D    ++   +++RPGG++     N       
Sbjct: 125 MTTIEALSGEA-ATFDAVLAMEVLEHVLDVAGFVRCCGALVRPGGLMFAATLNRTLKSFA 183

Query: 159 NMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREK 218
             + G  +YV    P+             P ++   +  A      +TGV VF       
Sbjct: 184 FAIVGA-EYVLGWAPRGTHDW---RRFISPRELARAMAAADLSAFDETGV-VFDPLQGGW 238

Query: 219 HQQRDC 224
               D 
Sbjct: 239 RLAHDT 244


>UniRef50_B9XIN5 Ubiquinone/menaquinone biosynthesis methyltransferase n=1
           Tax=bacterium Ellin514 RepID=B9XIN5_9BACT
          Length = 263

 Score =  120 bits (301), Expect = 6e-26,   Method: Composition-based stats.
 Identities = 38/176 (21%), Positives = 72/176 (40%), Gaps = 7/176 (3%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           F  IA  +       + G  R    W+     LA   P + R LD   G G     +A  
Sbjct: 43  FATIAPHYDLINDLQSFGLHR---FWKQRLLNLAHGRPGE-RALDLCCGTGDVTFALAAT 98

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV 125
           G + +  D S  M+  A+Q  +++    +++F++  AQ++    +   D++     L  +
Sbjct: 99  GMEAVGLDFSEPMLKVARQRTQSQNPKPSVRFLNGDAQNIP-FPDGSFDVVTISYGLRNL 157

Query: 126 ADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLS 181
           AD    L+ +  V +PGG L ++ +      +   +   F Y++  +P   K    
Sbjct: 158 ADLDLGLREMKRVAKPGGRLLVLDFGKPDNAVWRSLY--FTYLKFFVPVMGKVLCG 211


>UniRef50_Q97TL7 SAM-dependent methyltransferase n=2 Tax=Clostridium
           RepID=Q97TL7_CLOAB
          Length = 254

 Score =  120 bits (300), Expect = 6e-26,   Method: Composition-based stats.
 Identities = 39/159 (24%), Positives = 75/159 (47%), Gaps = 14/159 (8%)

Query: 44  QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQ 103
           +  ++LD G G G    ++A+ G  VI  DLS  MID+AK          N+ F    A 
Sbjct: 30  KDQKILDLGCGTGVLTNELAKNGATVIGTDLSKNMIDKAKTN------YPNLIFQVKDAT 83

Query: 104 DVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAG 163
           +++   E   D +  +AV  W+++   +L ++++ L+  G L   F   + +   + +  
Sbjct: 84  NLSFKNE--FDTVFSNAVFHWISNQEKLLHSIYTCLKDNGTLICEFGAQNNI---SQIQT 138

Query: 164 NFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQI 202
            F+ V   + +K     SP +     +  L L++AG+++
Sbjct: 139 AFEKV---IEQKGYSYCSPFFFPSKEEYKLLLDQAGFEV 174


>UniRef50_D1BE92 Methylase involved in ubiquinone/menaquinone biosynthesis n=2
           Tax=Actinomycetales RepID=D1BE92_SANKS
          Length = 236

 Score =  120 bits (300), Expect = 6e-26,   Method: Composition-based stats.
 Identities = 50/259 (19%), Positives = 92/259 (35%), Gaps = 25/259 (9%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M   ++D  A+ +      +      +     DL         +   +LDAG G G  A 
Sbjct: 1   MSADDYDRFADDYEAENASSLLNAYYERPAVLDLA-----GDVRGRTILDAGCGSGPLAA 55

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
           ++  RG  V+  D S  MID A++      + + +        +   + +   D ++   
Sbjct: 56  ELVTRGADVVGFDGSPAMIDLARRR-----LGEAVPLTVHDLTEPLPYDDETFDDVVASL 110

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDY--VQAGMPKKKKR 178
           VL ++ D  + L  +  VL+PGG L     +    +++      F        +    K 
Sbjct: 111 VLHYLEDWDAPLAEIRRVLKPGGRLIASVNHPFAQVLNAPTEDYFATRLYDEDVELAGKP 170

Query: 179 TLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQ 238
           T+   + R   +V   + +AG        VRV    + E     D    LL        +
Sbjct: 171 TVLTFWHRPLREVVRAVTDAGLS------VRV----IDEPAPSADTPADLLPPRIASGER 220

Query: 239 EPYITLGRYIHVTARKPQS 257
             +     ++ V A KP +
Sbjct: 221 SAFFC---FLFVVAEKPAA 236


>UniRef50_A8PNX2 3-demethylubiquinone-9 3-O-methyltransferase n=1 Tax=Rickettsiella
           grylli RepID=A8PNX2_9COXI
          Length = 234

 Score =  120 bits (300), Expect = 7e-26,   Method: Composition-based stats.
 Identities = 39/188 (20%), Positives = 75/188 (39%), Gaps = 7/188 (3%)

Query: 44  QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQ 103
           +  +V+D G G G  A  MA+RG +V   D S  +ID AK+ A    +   + +    A+
Sbjct: 49  KGKKVIDVGCGGGIFAEAMAQRGAEVTGIDKSGALIDVAKKHAADNQLP--IDYFSAEAE 106

Query: 104 DVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAG 163
             A+H     D++    +LE V  P S++Q    + +P   +     N +       + G
Sbjct: 107 SFATHQRESYDVVCCMELLEHVPCPLSLIQACSQLAKPNARIFFSTINRNPRAYFLAILG 166

Query: 164 NFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRD 223
             +++   +P+             P+++ L   +A   +    G+  ++  L+      D
Sbjct: 167 A-EHLLKILPRGTHDY---KKFIRPSELALAGRKAYLTLQKLQGIH-YNPILQHYALSDD 221

Query: 224 CYEALLEL 231
                L  
Sbjct: 222 IRINYLAA 229


>UniRef50_B0MSN4 Putative uncharacterized protein n=1 Tax=Alistipes putredinis DSM
           17216 RepID=B0MSN4_9BACT
          Length = 238

 Score =  120 bits (300), Expect = 7e-26,   Method: Composition-based stats.
 Identities = 47/207 (22%), Positives = 85/207 (41%), Gaps = 16/207 (7%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           FD IA  + R  +  +    +   LW+     +     Q  R+LD   G G  A+ MA R
Sbjct: 18  FDRIAPAYDRLNHTLS---FQIDKLWRRHVVRIVRRM-QPRRILDVATGTGDLALAMARR 73

Query: 66  --GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
             G QV+  DLS  M+  A++ A A G+ + +      A+ +    +  VD++     + 
Sbjct: 74  MRGVQVLGVDLSENMLAEARRKATACGLDERVVLSLGDAERL-EVADASVDVVTVAFGVR 132

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNA---------HGLLMHNMVAGNFDYVQAGMPK 174
              D  + L+ +  VL+PGG + ++ ++          +GL  H ++      +      
Sbjct: 133 NFGDLGAGLREIVRVLKPGGKVVILEFSTPRNPLFRRVYGLYSHRLLPAIGGMISKDRKA 192

Query: 175 KKKRTLSPDYPRDPAQVYLWLEEAGWQ 201
            +    S D    P      + EAG++
Sbjct: 193 YEYLPASVDEFPAPECFMAMMREAGFK 219


>UniRef50_C9LTF9 SmtA protein n=2 Tax=Veillonellaceae RepID=C9LTF9_9FIRM
          Length = 248

 Score =  120 bits (300), Expect = 7e-26,   Method: Composition-based stats.
 Identities = 54/215 (25%), Positives = 90/215 (41%), Gaps = 19/215 (8%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQ--KLRVLDAGGGEGQTAI 60
           +  +D  + KFS       +G    A  WQ   + +A   P+   LR+LD G G G  A+
Sbjct: 18  ESYWDARSPKFSAVRRRELEGS--DAARWQ---KFIASHLPEKKPLRILDVGTGAGFFAV 72

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
            +   GH+V   D+SA MID A++   A G   +++ ++    D     +   D+++   
Sbjct: 73  LLTRMGHEVTGIDMSAGMIDEAQKNLAAFGCWADLRKMNAQQLD---FSDESFDVVISRN 129

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPK------ 174
           +   + D     +    VLR GG+L L F + +G    +  A   D V  G+ +      
Sbjct: 130 LTWTLPDAMQAYREWRRVLRAGGML-LNFDSDYGETTFSA-ADAQDSVHTGICEALLIEC 187

Query: 175 -KKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
            K K  L     R P      LE+ G+ +     +
Sbjct: 188 NKIKDELRVSTHRRPLWDAALLEKLGFSVQYDADI 222


>UniRef50_A4B9Z3 3-demethylubiquinone-9 3-methyltransferase n=2 Tax=unclassified
           Gammaproteobacteria RepID=A4B9Z3_9GAMM
          Length = 247

 Score =  120 bits (300), Expect = 7e-26,   Method: Composition-based stats.
 Identities = 50/226 (22%), Positives = 90/226 (39%), Gaps = 23/226 (10%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKG------------QLRQAIL---WQDLDRVLAEMGP-Q 44
           M D   D     + R +  T               QLR   +   W+    +     P Q
Sbjct: 2   MSDSTIDLKEADYYRRLADTWWQPDGPFWPLHQLNQLRTRWIAEQWRKRHPMADSEQPLQ 61

Query: 45  KLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQD 104
            L VLD G G G  +  +A  G QV   D+ A+ I+ A++ A+A+ ++   + I   A  
Sbjct: 62  GLHVLDVGCGGGILSEALARLGAQVHGVDVVARNIEVARRHAKAQNLAVTYECIETDA-- 119

Query: 105 VASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGN 164
                    D++    V+E VA+    +    ++++PGG   +   N + L     + G 
Sbjct: 120 -LVRRGDQYDIVFNMEVVEHVANVDLFMAQCNALVKPGGTQFVATINRNWLSFLIAIIGA 178

Query: 165 FDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRV 210
            +Y+   +PK   +       + P ++  +L   G ++  + GV V
Sbjct: 179 -EYITGYLPKGTHQY---GKLQKPEEIRRYLALGGLKVTAREGVAV 220


>UniRef50_A8TN90 Ubiquinone biosynthesis O-methyltransferase n=1 Tax=alpha
           proteobacterium BAL199 RepID=A8TN90_9PROT
          Length = 239

 Score =  120 bits (300), Expect = 7e-26,   Method: Composition-based stats.
 Identities = 51/209 (24%), Positives = 82/209 (39%), Gaps = 8/209 (3%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTK-GQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTA 59
           M DR +D        + Y   +   +R A      DR         L VLD G G G  +
Sbjct: 12  MADRWWDPDGPHGPLHRYVPARMAIIRDAARTVASDRKDQRRPMAGLSVLDIGCGGGLLS 71

Query: 60  IKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFH 119
             M   G  V   D     I  A   A   GV  ++ +   AA+D+A+      D+++  
Sbjct: 72  EPMTRLGATVTGVDADTAGIAAAVSHA--AGVGLDIAYRAGAAEDLATEG-RVFDMVVAS 128

Query: 120 AVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRT 179
            V+E VAD  +  + L +++RPGG+L L   N         +    +YV   +P+     
Sbjct: 129 EVIEHVADRDAFAEALAALVRPGGLLVLTTINRTRRSYAMAIVAA-EYVLRWVPRGTHDW 187

Query: 180 LSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
                   P ++   LE+ G+ +    G+
Sbjct: 188 ---SKFPTPDELTGLLEQRGFAVETPIGL 213


>UniRef50_B0A8V0 Putative uncharacterized protein n=1 Tax=Clostridium bartlettii DSM
           16795 RepID=B0A8V0_9CLOT
          Length = 247

 Score =  119 bits (299), Expect = 8e-26,   Method: Composition-based stats.
 Identities = 48/217 (22%), Positives = 93/217 (42%), Gaps = 34/217 (15%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQK-LRVLDAGGGEGQTAIK 61
           +  +   ++ F        K   RQ  LWQD   ++A +  ++ L++LD G G G  ++ 
Sbjct: 13  ENYWSKRSDDFFDLRIEELKSDKRQ--LWQD--EIIANLPDKEHLKILDVGCGPGFFSVI 68

Query: 62  MAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
           ++  GH VI  DL+  MI +A + A+   +  ++ F    AQ++    +   D+++   +
Sbjct: 69  LSSLGHDVIGIDLTESMIQKADEIADI--LDYDIDFRVMNAQEL-DFDDEEFDVVISRNL 125

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLL-------------MHNMVAGNF--- 165
              + D     +  + VL+  GVL L F   +G +              HNM+  +    
Sbjct: 126 TWTLPDIEKAYKEWYRVLKKDGVL-LNFDADYGKVSLKEEMKSLGEEHSHNMMDSSLVKE 184

Query: 166 -DYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQ 201
            D ++  +   K+R    D          +L+E G++
Sbjct: 185 CDDIKQELEISKRRRPMWD--------EKFLQEIGFE 213


>UniRef50_UPI0001B57FBF MCP methyltransferase, CheR-type n=1 Tax=Streptomyces sp. AA4
           RepID=UPI0001B57FBF
          Length = 246

 Score =  119 bits (299), Expect = 8e-26,   Method: Composition-based stats.
 Identities = 63/257 (24%), Positives = 104/257 (40%), Gaps = 25/257 (9%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           +D +A  F+          +R+ + W      L ++  +  RVLD G GEG    ++ + 
Sbjct: 8   YDQVATAFADV--EAIISFVRENLEWPSFKNALGDL--RGARVLDVGCGEGSFTRRIKQL 63

Query: 66  G-HQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVAS-HLETPVDLILFHAVLE 123
           G  QV+  DLS  MI  A+QA     +      I    QD+A+  L+   D++    VL 
Sbjct: 64  GAAQVVGTDLSPGMIALARQAEARNPLG-----ITHEVQDLAAMPLQGEFDVVTAIHVLH 118

Query: 124 WVADPRSVLQ----TLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRT 179
           + AD R  +Q    T+ + L+PGG L+++  NA         AG   Y  A   +  K  
Sbjct: 119 Y-ADTRETMQTMAKTMHANLKPGGRLAVLSANADSSEESETAAGFRTYRPANPQEGDKFK 177

Query: 180 LSP-DYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQ 238
           ++    P    +V+ W  E   +I+   G   F +      +  +            C +
Sbjct: 178 VAVLTTPPTEIEVHHWPTETIVEILETAG---FTNVSWSLVRPSETVAPADRDRAARCAK 234

Query: 239 EPYITLGRYIHVTARKP 255
            P       + +TA KP
Sbjct: 235 NP-----TSLTLTATKP 246


>UniRef50_C3YXC3 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
           RepID=C3YXC3_BRAFL
          Length = 317

 Score =  119 bits (299), Expect = 8e-26,   Method: Composition-based stats.
 Identities = 46/216 (21%), Positives = 88/216 (40%), Gaps = 16/216 (7%)

Query: 4   RNFDDIAEKFSRNIYGTTKG-----QLRQAILWQDLDR---VLAEMGP-QKLRVLDAGGG 54
           + F+ +A K+     G  KG     +LR  ++   L +   +  +  P + LR+LD G G
Sbjct: 78  KKFNALASKWWDTK-GELKGLHSMNRLRVPMIRDTLVKHHSISKKSRPLEGLRILDVGCG 136

Query: 55  EGQTAIKMAERGHQVILCDLSAQMIDRAKQA-AEAKGVSDNMQFIHCAAQDV-ASHLETP 112
            G  ++ +A+ G QV   D S + +  A    A    + D + F H   +D+ AS +   
Sbjct: 137 GGILSVPLAKLGAQVTGLDASEEAVKAATAHMARDPSLKDTLTFTHGTVEDLVASEVRDY 196

Query: 113 VDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGM 172
            D ++   V+E V      + +   +++PGG L     N      +  V    +Y+   +
Sbjct: 197 YDALVASEVIEHVDALDDFVGSSCDLVKPGGSLFFTTINRTTQSYYLAVIAA-EYIVGVV 255

Query: 173 PKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
           P+      + +    P ++   L+          G+
Sbjct: 256 PRGTH---NWNKFVKPEELKDELKANNCHPRLIHGM 288


>UniRef50_C6P0T7 Methyltransferase type 11 n=1 Tax=Sideroxydans lithotrophicus ES-1
           RepID=C6P0T7_9PROT
          Length = 270

 Score =  119 bits (299), Expect = 8e-26,   Method: Composition-based stats.
 Identities = 35/182 (19%), Positives = 72/182 (39%), Gaps = 7/182 (3%)

Query: 29  ILWQDLDRVLAEMGPQK-LRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAE 87
           +  Q  D  +A    +    VLD   G G  A+++A++  QV   D S  M+   +   E
Sbjct: 26  VFEQFADEAIAASNLKPNSTVLDVACGPGTLALRLAQQAGQVHGIDFSEAMLAIFRNKIE 85

Query: 88  AKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSL 147
             G   N+      AQ +  + +   D       L +  D +     ++  L+PGG +++
Sbjct: 86  QAG-HRNIALHCGDAQTLP-YADATFDAAFSLFGLMFFPDRQKGFAEIYRTLKPGGSIAI 143

Query: 148 MFYNAHGLLMHN-MVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKT 206
             +           + G    ++  +P+ ++   + +    P +    +EEAG++ +   
Sbjct: 144 TSWAPVDQSPAMQTMFGALRAIKPDLPQPQRSVATLEN---PQRFRQEMEEAGFRYIEIR 200

Query: 207 GV 208
            V
Sbjct: 201 SV 202


>UniRef50_B0C3T5 Methyltransferase n=8 Tax=Bacteria RepID=B0C3T5_ACAM1
          Length = 214

 Score =  119 bits (299), Expect = 9e-26,   Method: Composition-based stats.
 Identities = 43/200 (21%), Positives = 81/200 (40%), Gaps = 19/200 (9%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
           + +D IAEK+++         +     +Q   ++  E     + VL+ G G G TAI  A
Sbjct: 6   QFWDKIAEKYAKQ-------PISDEAAYQKKLQITREYFQPSMNVLEFGCGTGSTAIAHA 58

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
              H +   D S++MID A+  A A+ +  N+ F   +  ++    ++  D +L   VL 
Sbjct: 59  PYVHHIQAIDFSSKMIDIAQAKAAAQNI-LNVTFEQASIDELNV-PDSSYDAVLGLNVLH 116

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSP- 182
            + +  + +  +  +L+PGG                 +     + +   P  K   L P 
Sbjct: 117 LLENKEAAIAQVHKMLQPGGCFITST---------VCLGDTMAWFKLIAPVGKVLGLFPL 167

Query: 183 DYPRDPAQVYLWLEEAGWQI 202
                   +   L +AG++I
Sbjct: 168 VKIFTVKDLETSLTDAGFEI 187


>UniRef50_A1R990 Menaquinone biosynthesis methyltransferase ubiE n=56
           Tax=Actinobacteria (class) RepID=UBIE_ARTAT
          Length = 253

 Score =  119 bits (298), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 55/241 (22%), Positives = 92/241 (38%), Gaps = 30/241 (12%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           FDD+A K+       + GQ R+   W+ +  V A       +VLD   G G ++   A+ 
Sbjct: 17  FDDVAPKYDVVNDVLSMGQTRR---WRRIV-VDAMDVKVGQKVLDLAAGTGTSSEPYADA 72

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV 125
           G  V+ CD S  M+   K+         ++ FI   A ++    +   D       L  V
Sbjct: 73  GVDVVACDFSLGMLKVGKRR------RPDIDFIAGDATNLP-FADNSFDASTISFGLRNV 125

Query: 126 ADPRSVLQTLWSVLRPGGVLSLMFYN-AHGLLMHNMVAGNFDYVQAGMPK-KKKRTLSPD 183
            +PR  L+ +  V +PGG L +  ++     L  N+     +Y+   +P    K + +PD
Sbjct: 126 VEPRKALEEMLRVTKPGGRLVIAEFSHPVVPLWRNLYT---EYLMRALPAIATKVSSNPD 182

Query: 184 YP----------RDPAQVYLWLEEAGWQIMGKT----GVRVFHDYLREKHQQRDCYEALL 229
                        D   +  WL +AGW  +       G+   H   +    +     A L
Sbjct: 183 AYVYLAESIRAWPDQDHLAQWLSDAGWTDITYRNLSGGIVAVHRAQKPDEHRESVPVAKL 242

Query: 230 E 230
            
Sbjct: 243 R 243


>UniRef50_B2WBS7 Methyltransferase UbiE n=2 Tax=Pleosporineae RepID=B2WBS7_PYRTR
          Length = 274

 Score =  119 bits (298), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 35/128 (27%), Positives = 67/128 (52%), Gaps = 6/128 (4%)

Query: 37  VLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQ--VILCDLSAQMIDRAKQAAEAKGVSDN 94
           +L  +    L++LD G G G  ++ +A R  Q  V   D SA++I++A++ AE KGV+ N
Sbjct: 29  LLPYLSNPSLKILDVGCGPGTISVDLATRVPQGFVYAIDPSAEVIEKARKHAEEKGVT-N 87

Query: 95  MQFIHCAAQD---VASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYN 151
           ++F      +   +    E   D++  H VL+ + DP   ++ +  + +PGG+L++   N
Sbjct: 88  VRFEVGDIFEWNKLVGLEEAGFDVVHAHQVLQHLQDPLGAMKAMKRLAKPGGLLAIRDCN 147

Query: 152 AHGLLMHN 159
              +  + 
Sbjct: 148 YSAMDWYP 155


>UniRef50_B1I444 Methyltransferase type 11 n=1 Tax=Candidatus Desulforudis
           audaxviator MP104C RepID=B1I444_DESAP
          Length = 215

 Score =  119 bits (298), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 40/207 (19%), Positives = 75/207 (36%), Gaps = 29/207 (14%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M+   F+++A+++   +      +L + +    L +           VLD G G G    
Sbjct: 1   MRREFFNNLADRWDDLVPPGAASKLAEIVAGSGLRK--------GAHVLDVGCGTGLLVP 52

Query: 61  KMAERGHQ---VILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLIL 117
            + ER  +   V   D +A M+ RA   A       N++F+      +        D + 
Sbjct: 53  FLLERAGERGTVTGVDFAAAMVQRAGAKA----FGPNVRFVEADVAALPFE-PGTFDAVF 107

Query: 118 FHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKK 177
            + VL  + D    LQ L  VL+PGG+L +                        M +   
Sbjct: 108 CNNVLPHLPDKPGALQELNRVLKPGGLLVI-------------CHTESREAVNRMHRHIG 154

Query: 178 RTLSPDYPRDPAQVYLWLEEAGWQIMG 204
             +  D      ++   L++AG+ ++ 
Sbjct: 155 GPVGADLLPTVEELRQMLQDAGYSVLD 181


>UniRef50_Q1GR70 3-demethylubiquinone-9 3-methyltransferase n=1 Tax=Sphingopyxis
           alaskensis RepID=Q1GR70_SPHAL
          Length = 272

 Score =  119 bits (298), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 43/214 (20%), Positives = 77/214 (35%), Gaps = 35/214 (16%)

Query: 25  LRQAILWQDLD-----RVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMI 79
           +R A + + +D                 VLD G G G     +A  G +VI  D + + I
Sbjct: 37  VRLAYIREQIDGHWHVDARERHPLAGKHVLDVGCGAGLLCEPLARMGAKVIGIDAAPENI 96

Query: 80  DRAKQAAEAKGVSDNM----------QFIHCAAQDVASHLE---------------TPVD 114
             AK  A  +G++ +            F+    + +    +                  D
Sbjct: 97  AAAKDHAAGQGLAISYFAGELADLPNPFVSSEVETLLGSADLRGVSTSLDTNGEGKGQFD 156

Query: 115 LILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPK 174
           L+    V+E V DP   +  L + L PGG++ L   N    +   ++          +P+
Sbjct: 157 LVTSMEVIEHVVDPAVFVAELAARLAPGGLMILSTPNR--TIASKLLLVEAAERIGAVPR 214

Query: 175 KKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
                   D    P ++   LE AG +++ +TG+
Sbjct: 215 GTHDW---DRFLKPEELTKLLEGAGLEVIDRTGL 245


>UniRef50_A6TPQ5 Methyltransferase type 11 n=1 Tax=Alkaliphilus metalliredigens QYMF
           RepID=A6TPQ5_ALKMQ
          Length = 251

 Score =  119 bits (298), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 38/177 (21%), Positives = 78/177 (44%), Gaps = 7/177 (3%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
           +  ++  A  FS ++    +   +    W  L +    M  +KL+VLD G G G  A+ +
Sbjct: 8   EDYWNQRARGFSLSVVEELEDDKKDQ--WLQLFKKYG-MTERKLKVLDVGTGSGFFAVLL 64

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
           A+ GH V   D +  M+  A++ A    V  +++     AQ++    +   DLI+   ++
Sbjct: 65  AQEGHDVTGIDYTPNMLKHAEETARKFNVKLDLR--QMDAQNL-EFEDESFDLIVTRNLM 121

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRT 179
             +  P    +    VL+ GG +     N +  L  ++    ++ ++  +P ++  T
Sbjct: 122 WNLEFPEKAYREWIRVLKKGGKIINFDGNYYLHLHDDVYKEGYEKIEY-VPDRQGHT 177


>UniRef50_B4V763 Putative uncharacterized protein n=4 Tax=Streptomyces
           RepID=B4V763_9ACTO
          Length = 218

 Score =  119 bits (298), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 41/145 (28%), Positives = 63/145 (43%), Gaps = 6/145 (4%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
            +DD A  F          Q      W  L R  + +   +  VLDAG G G  ++ +AE
Sbjct: 11  YWDDAAASFDDE-PDHGLRQEHTRAAWARLLR--SWLPDARADVLDAGCGTGSLSLLLAE 67

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
            GH+V   DL+  M++RA+    A G +    F+   A       +   D +L   +L  
Sbjct: 68  AGHRVTGVDLAPHMVERAEAKLAAAGRAGR--FLVGDAA-APPTGQGRYDAVLSRHLLWT 124

Query: 125 VADPRSVLQTLWSVLRPGGVLSLMF 149
           + DP + L+   + L PGG L L+ 
Sbjct: 125 LPDPHAALREWVARLNPGGRLVLVE 149


>UniRef50_D1RIV9 3-demethylubiquinone-9 3-O-methyltransferase n=1 Tax=Legionella
           longbeachae D-4968 RepID=D1RIV9_LEGLO
          Length = 231

 Score =  119 bits (298), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 51/217 (23%), Positives = 89/217 (41%), Gaps = 14/217 (6%)

Query: 11  EKFSRNI--YGTTKGQLR--QAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERG 66
            KF+++   +  T+G LR    I    LD +   +    L VLD G G G     MA  G
Sbjct: 14  HKFAQHAKLWWDTEGPLRTLHDINGIRLDFIQQHVQLSHLNVLDVGCGGGILCETMANAG 73

Query: 67  HQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVA 126
             V   D     I  A++ A  KG   N+ +   + +   ++     D+I    +LE V 
Sbjct: 74  ANVTGIDAEIDTILVAQEHA--KGSHLNVDYFCTSIE---AYKNPCFDVITCMEMLEHVQ 128

Query: 127 DPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPR 186
           +P+ VLQ    +L+P G L L   +         +    +Y+   +PK+       D   
Sbjct: 129 NPKLVLQHCRRLLKPKGFLFLSTISRTVKAYLTAIVAA-EYLLNLLPKQTHDY---DKFI 184

Query: 187 DPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRD 223
            P+++       G++++   G+  ++  LR+     D
Sbjct: 185 KPSELLAITRSLGFKLVDMKGMD-YNPLLRKASLGTD 220


>UniRef50_Q9EYI2 SnogM n=1 Tax=Streptomyces nogalater RepID=Q9EYI2_STRNO
          Length = 278

 Score =  119 bits (298), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 36/138 (26%), Positives = 60/138 (43%), Gaps = 4/138 (2%)

Query: 13  FSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER-GHQVIL 71
           +          +  Q +     +R+  E+GP   RVLD G G G  A+++A   G +V+ 
Sbjct: 35  WDSLPADAGMDRASQRLTEMMTERI--EVGP-GQRVLDIGCGTGAPAVQLARATGAEVVG 91

Query: 72  CDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSV 131
             +S + +  A   AE +GV++ + F    A           D + F   +  + D  + 
Sbjct: 92  ITISPEQVRLATAHAEREGVAERVTFRCADASAELPFPADSFDAVWFFESIFHLPDRLTA 151

Query: 132 LQTLWSVLRPGGVLSLMF 149
           L+    VLRPGG L+L  
Sbjct: 152 LRRAAEVLRPGGRLALTD 169


>UniRef50_B8G1N6 Methyltransferase type 11 n=1 Tax=Desulfitobacterium hafniense
           DCB-2 RepID=B8G1N6_DESHD
          Length = 252

 Score =  118 bits (297), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 37/170 (21%), Positives = 73/170 (42%), Gaps = 4/170 (2%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
           +  +   AE F+         +  +  LW+ + +   +   +KL +LD G G G   I +
Sbjct: 8   NDYWSTQAEAFTEISVDELTSE--KNALWKSILKPFVQ-TDRKLEILDVGCGAGFFEIFL 64

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
           +  GH V   D + +M+  A++  E  G  +  + +   AQ++A   ++  D+++   + 
Sbjct: 65  SCLGHHVTAVDFNGKMLAEARKNIEKLGRPELTKLMQMDAQNLA-FQDSVFDIVISRNMT 123

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGM 172
             + +P+        VL+P G L     N    L  +    NF+  QA +
Sbjct: 124 WVLENPQRAYGEWLRVLKPHGKLINFDANWFLHLRDDTARRNFEEGQAAV 173


>UniRef50_Q1JXN0 Methyltransferase type 11 n=1 Tax=Desulfuromonas acetoxidans DSM
           684 RepID=Q1JXN0_DESAC
          Length = 264

 Score =  118 bits (297), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 52/264 (19%), Positives = 97/264 (36%), Gaps = 32/264 (12%)

Query: 11  EKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQK-LRVLDAGGGEGQTAIKMAERGHQV 69
           +++S+      + Q     +  DLD +L  + PQK  +VLD   G G TA+ +A    QV
Sbjct: 12  DQYSQVGDAYVRSQTHAKGV--DLDYLLNMVQPQKDWKVLDVATGGGHTALILAPYVQQV 69

Query: 70  ILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPR 129
           I  DL+  M++ AK+    +    N+ F    A+++    +   DL+            +
Sbjct: 70  IAVDLTPNMVETAKKFVCDEKGQTNVTFQLADAENLPFE-DGSFDLVTCRIAAHHFPACQ 128

Query: 130 SVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPA 189
             +     VL+ GG+L++  +       H +    F+ +         R  S        
Sbjct: 129 KFIAESVRVLKQGGLLAVQDHVLPAEENHALYVDQFERL---------RDPSHFRAYSEQ 179

Query: 190 QVYLWLEEAGWQIMGKTGV---RVFHDYLREKHQQRDCYEALLEL-----ETRYCRQEPY 241
           Q     E  G Q+     +     F D+ +  +   +  + L+ +           Q+P+
Sbjct: 180 QWRQMFELGGLQVQQTRQLTKRHNFIDWAKRMNCTEETLDELVAMMKNAPNAVKAWQKPF 239

Query: 242 IT-----------LGRYIHVTARK 254
                        +  +I V  RK
Sbjct: 240 PDADHFGGIETSFVNHHIIVVGRK 263


>UniRef50_A2R2U4 Contig An14c0090, complete genome n=32 Tax=cellular organisms
           RepID=A2R2U4_ASPNC
          Length = 266

 Score =  118 bits (297), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 41/191 (21%), Positives = 81/191 (42%), Gaps = 16/191 (8%)

Query: 31  WQDLDRVLAEMGP---QKLRVLDAGGGEGQTAIKMAERG--HQVILCDLSAQMIDRAKQA 85
           W+ +   +  + P     + +LD G G G   +  A       V   +  +  +D+A+  
Sbjct: 18  WRTISNSVPYVLPYLKPNMTILDIGCGPGSITVDFARHVPEGHVTGVEYVSDPLDQARNL 77

Query: 86  AEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRP-GGV 144
           A ++G++ N+ F       +    +   DL+  H VL+ +ADP   L+ +  V +P GG+
Sbjct: 78  ASSQGIT-NITFQVADIHSLP-FADNTFDLVHVHQVLQHIADPVLALREMRRVAKPDGGI 135

Query: 145 LSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGW---Q 201
           ++    +A      N     +  +   M ++K        P   +++++W EEAG+   +
Sbjct: 136 IAARESSAMTWYPENKGIELWLDIATKMAREKGG-----NPHPGSKIHVWAEEAGFPQER 190

Query: 202 IMGKTGVRVFH 212
           I    G   F 
Sbjct: 191 IKKTAGSWCFS 201


>UniRef50_D0BKF2 SmtA protein n=1 Tax=Granulicatella elegans ATCC 700633
           RepID=D0BKF2_9LACT
          Length = 258

 Score =  118 bits (297), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 36/166 (21%), Positives = 70/166 (42%), Gaps = 6/166 (3%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
             ++     +S+      +G  R+   W+     L     + L+VLD G G G   I + 
Sbjct: 9   HYWNHRYSGYSKVNQKELEGIQRER--WKKQFERLLPAN-KNLKVLDIGTGPGFFTIILE 65

Query: 64  ERGH-QVILCDLSAQMIDRAKQAAEAKGVSDN-MQFIHCAAQDVASHLETPVDLILFHAV 121
           E G+  ++  D+S +M++ AK+  +  G  D+ ++ I   AQ +        D+I+   +
Sbjct: 66  ELGYTNIMGIDVSEKMLEVAKENIQKYGKKDSSIELIQMDAQKL-EFKPESFDIIVSRNL 124

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDY 167
              +  P+        VL+P G L +   N +  L +  +   F+ 
Sbjct: 125 TWNLEKPQQAYSEWLRVLKPNGALFIFDANWYAFLQNESLEKEFEA 170


>UniRef50_Q47PB3 S-adenosylmethionine (SAM)-dependent methyltransferase n=1
           Tax=Thermobifida fusca YX RepID=Q47PB3_THEFY
          Length = 251

 Score =  118 bits (297), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 47/188 (25%), Positives = 77/188 (40%), Gaps = 14/188 (7%)

Query: 16  NIYGTTKGQLRQAILWQDLDRVLAEMGPQKL-RVLDAGGGEGQTAIKMAERGHQVILCDL 74
           +++       R + +      +L  +      RVLDAG G G    ++A  G  V+  D+
Sbjct: 4   HVWDAELYDARHSFVAAHGTALLDLLNAAPGERVLDAGCGTGDHVAQLAAAGVDVLGVDI 63

Query: 75  SAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQT 134
           S +M+ RA            +       + +    E   D +L +AVL WV +      +
Sbjct: 64  SPEMVARAAARF------PGIPVTVADLRALPFREE--FDAVLSNAVLHWVPEADQAAAS 115

Query: 135 LWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLW 194
           L +VLRPGG L +      G +     A +    + G+P+      SP Y    AQ    
Sbjct: 116 LRAVLRPGGRL-VAELGGAGNIATLTTAIHELRAEWGLPQAA----SPWYFPTVAQYARV 170

Query: 195 LEEAGWQI 202
           LE AG+++
Sbjct: 171 LENAGFEV 178


>UniRef50_Q235E0 Ubiquinone biosynthesis O-methyltransferase family protein n=1
           Tax=Tetrahymena thermophila SB210 RepID=Q235E0_TETTH
          Length = 274

 Score =  118 bits (296), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 35/195 (17%), Positives = 83/195 (42%), Gaps = 8/195 (4%)

Query: 40  EMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAE-AKGVSDNMQFI 98
           ++  + L++LD G G G  +  +   G  V   D +   I  A    +  + +   + + 
Sbjct: 84  KLPLKNLQILDVGCGGGLLSESLCRLGANVTGLDANENSISIANNHKKLDQFLEQKLNYK 143

Query: 99  HCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMH 158
              A++++S      DL+    V+E + D    + TL  ++RPGG++ L           
Sbjct: 144 LGTAEELSSQ-NIQYDLVTCMEVIEHIQDKEQFIATLSQLVRPGGMIFLSTMEKTRESYL 202

Query: 159 NMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTG--VRVFHDYLR 216
            ++ G  +Y+   +PK        +   +   +   LE+ G++I+   G    + ++ + 
Sbjct: 203 KLILGA-EYIAKLVPKGTHDW---NKFINSEDLSALLEDNGFKILKIQGFSYDIINNQME 258

Query: 217 EKHQQRDCYEALLEL 231
           + + + +   + ++L
Sbjct: 259 KSNNKMNYLISAIKL 273


>UniRef50_Q9ALM7 Methyltransferase-like protein n=2 Tax=Saccharopolyspora
           RepID=Q9ALM7_9PSEU
          Length = 275

 Score =  118 bits (296), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 54/251 (21%), Positives = 89/251 (35%), Gaps = 27/251 (10%)

Query: 18  YGTTKGQLRQAILWQDLDRVLAE--MGPQKLRVLDAGGGEGQTAIKMAERGH-QVILCDL 74
           Y    G+         L  ++AE  +    +R+LD G G GQ A+++A     Q+    +
Sbjct: 37  YWENDGRASWQQAADRLTDLVAERTVLDGGVRLLDVGCGTGQPALRVARDNAIQITGITV 96

Query: 75  SAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQT 134
           S   +  A   A  +G+S  + F    A  +  + +   D       L  +++P   ++ 
Sbjct: 97  SQVQVAIAADCARERGLSHRVDFSCVDAMSLP-YPDNAFDAAWAMQSLLEMSEPDRAIRE 155

Query: 135 LWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLW 194
           +  VL+PGG+L +                       GMP    R  +        Q+   
Sbjct: 156 ILRVLKPGGILGVTEVVKR-------------EAGGGMPVSGDRWPTGLRICLAEQLLES 202

Query: 195 LEEAGWQIMGKTGV----RVFHDYLREKHQQRDCYE------ALLELETRYCRQEPYITL 244
           L  AG++I+    V    R F     E+              A+       C  E Y   
Sbjct: 203 LRAAGFEILDWEDVSSRTRYFMPQFAEELAAHQHGIADRYGPAVAGWAAAVCDYEKYAHD 262

Query: 245 GRYIHVTARKP 255
             Y  +TARKP
Sbjct: 263 MGYAILTARKP 273


>UniRef50_Q2GKA5 3-demethylubiquinone-9 3-methyltransferase n=7 Tax=Anaplasma
           RepID=Q2GKA5_ANAPZ
          Length = 236

 Score =  118 bits (296), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 40/187 (21%), Positives = 79/187 (42%), Gaps = 13/187 (6%)

Query: 32  QDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGV 91
           Q +   L E      R+LD G G G     MA  G  V   D   + I+ A+Q A  +G+
Sbjct: 37  QYILENLQEATNSGKRLLDIGCGGGLICEAMARLGFSVTGVDPCREGIEAARQHAAIEGL 96

Query: 92  SDNMQFIHCAAQDVASHLE-TPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFY 150
             ++++     +      E +  D+I    V+E + D    L +   +L+PGG+L +   
Sbjct: 97  --DIEYHFTDIESFIHSSECSSYDIITLMEVVEHIPDLTEFLSSSCKLLKPGGMLFISTL 154

Query: 151 NAHGLLMHNMVAGNF--DYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
           N     + +M+ G    +Y+   +P    +         P++++  L ++   +    G+
Sbjct: 155 NRT---IKSMLLGKIAAEYILRMVPPGTHQW---KKFVKPSEIHDALLKSRVLVKDIKGI 208

Query: 209 --RVFHD 213
             ++ H+
Sbjct: 209 TYKILHN 215


>UniRef50_Q5GT88 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-benzoquinol methylase
           n=9 Tax=Wolbachia RepID=Q5GT88_WOLTR
          Length = 402

 Score =  118 bits (296), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 35/174 (20%), Positives = 77/174 (44%), Gaps = 8/174 (4%)

Query: 36  RVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNM 95
           + L +   +KL +LD G G G  +  +A  G  V+  D+  + I  A+  A+  G+  N+
Sbjct: 211 KELKKCDLKKLSLLDVGCGGGILSESIARVGINVLGIDVCEENIKVAQSHAKKVGL--NI 268

Query: 96  QFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGL 155
           ++ H + ++++       D++L   V+E V +    ++    +L+P G++ +   N    
Sbjct: 269 EYTHTSIEELS--NNQKYDVVLLMEVVEHVDNLELFIKKAIELLKPEGLIFISTINRTFK 326

Query: 156 LMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVR 209
                + G  +Y+   +PK      + +    P+++   L E    +    G+ 
Sbjct: 327 SFFLAIIGA-EYILNWLPKGTH---NWNKFLKPSEIANHLREGNVTLQDMAGME 376


>UniRef50_B6Q7B1 UbiE/COQ5 methyltransferase, putative n=1 Tax=Penicillium marneffei
           ATCC 18224 RepID=B6Q7B1_PENMQ
          Length = 272

 Score =  118 bits (296), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 40/179 (22%), Positives = 85/179 (47%), Gaps = 11/179 (6%)

Query: 37  VLAEMGPQKLRVLDAGGGEGQTAIKMA---ERGHQVILCDLSAQMIDRAKQAAEAKGVSD 93
           +L  + P  ++VLD G G G   + +A    RG+ +   + +  ++ +A+  AE KGV  
Sbjct: 34  ILPHLKPD-MKVLDIGCGPGTITVDLASYVPRGY-ITGLESAEGVLTQARALAEEKGVK- 90

Query: 94  NMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAH 153
           N+ F+   A  +A + +   D+++ H VL+ V DP  +L+ ++ V + GG ++    +  
Sbjct: 91  NIDFVVGDANGLA-YEDQSFDVVICHQVLQHVRDPIGILKEMYRVAKVGGFVAARESDYG 149

Query: 154 GLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGW-QIMGKTGVRVF 211
           G + H  + G  ++  + +  +  R    + P     ++ W  +AG   +   +    +
Sbjct: 150 GFVWHPSIDGLSEW--SNLYDRVTRNNGGE-PNAGRMLHSWARQAGLADVKCSSSTWCY 205


>UniRef50_C6A0V9 Cyclopropane-fatty-acyl-phospholipid synthase superfamily n=3
           Tax=Thermococcus RepID=C6A0V9_THESM
          Length = 245

 Score =  118 bits (295), Expect = 3e-25,   Method: Composition-based stats.
 Identities = 49/227 (21%), Positives = 101/227 (44%), Gaps = 29/227 (12%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMG-PQKLRVLDAGGGEGQTA 59
           M+   +++    F R        +       +++D +L E   P+  ++LD G G G+ +
Sbjct: 1   MKKHEWEEF---FDREA-DYYLQEAFTKHTKKEIDFLLEEFKLPEGAKILDVGCGVGRHS 56

Query: 60  IKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILF- 118
           +++A+RG++V   D+S +M+++A++ A+ +GV   ++FI   A   A       D  +  
Sbjct: 57  LELAKRGYRVTGVDISQKMLEKAEERAQKEGVE--VEFIKADATKFAR--NEKFDAAVCL 112

Query: 119 ----HAVLEWVADP----RSVLQTLWSVLRPGGVLSLMFYNAHGLLMH----NMVAGNFD 166
                ++L    DP     ++L+ ++  L+PGG   L   +A   +      ++  G FD
Sbjct: 113 CEGAFSLLGSSDDPIEHDLAILRNVYKSLKPGGKFILTALSALSRVKKATNEDIAKGLFD 172

Query: 167 ------YVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTG 207
                 Y +   P   K  +  +    P ++YL     G+++    G
Sbjct: 173 PNTMTFYEELEAPDGTKVAIR-ERVYVPTELYLMFRMVGFEVKAIWG 218


>UniRef50_A7AUT3 Ubiquinone biosynthesis O-methyltransferase family protein n=2
           Tax=Babesia bovis RepID=A7AUT3_BABBO
          Length = 556

 Score =  118 bits (295), Expect = 3e-25,   Method: Composition-based stats.
 Identities = 39/190 (20%), Positives = 75/190 (39%), Gaps = 25/190 (13%)

Query: 44  QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQA--------AEAKGVSD-- 93
             +R+LD G G G  +  +A+ G  V+  D S ++I+ AKQ             G+SD  
Sbjct: 102 NGVRILDVGCGGGILSEILAKCGAHVVGIDPSKELIEVAKQHRDTDLVYDCAKLGLSDEC 161

Query: 94  --NMQFIHCAAQDVA-SHLETPVDLILFHAVLEWVAD--PRSVLQTLWSVLRPGGVLSLM 148
             N+++I    +  A SH +   D+++   V+E V +   ++ + ++  + +PGG++   
Sbjct: 162 SRNLEYIQGTVESYAQSHHKELFDIVVASEVIEHVPNIQKQAFIDSIARLTKPGGLVVFT 221

Query: 149 FYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTG- 207
                          N  + +       K T        P  +      +G   + + G 
Sbjct: 222 TPGR----SLKSCVINIGFAERVFKTVPKDTHRYTLFVSPESLSRSCANSGLSELCRQGI 277

Query: 208 -----VRVFH 212
                +R FH
Sbjct: 278 FYLPYIRRFH 287


>UniRef50_Q8RJX7 Methyl transferase n=1 Tax=Stigmatella aurantiaca
           RepID=Q8RJX7_STIAU
          Length = 256

 Score =  117 bits (294), Expect = 3e-25,   Method: Composition-based stats.
 Identities = 38/181 (20%), Positives = 71/181 (39%), Gaps = 5/181 (2%)

Query: 30  LWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAK 89
            + +L      + P K+RVLD G G G  A + +++G +V   D SA  I+ AK  +   
Sbjct: 34  YFHNLLTNRIGLDPTKVRVLDVGCGGGLLAEEFSKKGWKVTGVDQSAPSIELAKAHSAKV 93

Query: 90  GVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMF 149
           G+  N+ +    AQ +    +   D++    VLE +    + +     VL+ GGV     
Sbjct: 94  GL--NIDYHVSKAQKLPFE-DETFDIVYCCDVLEHIPTYPAAVAESARVLKKGGVYLYET 150

Query: 150 YNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVR 209
            N   +     +    ++    +               P +++  +  A  Q +   G+ 
Sbjct: 151 INRTFMSKMIAIKMLQEWSWTRVIPDDVH--DWKMFIRPEELHNAMHAAKIQNVETAGMT 208

Query: 210 V 210
           V
Sbjct: 209 V 209


>UniRef50_B4U0G0 S-adenosylmethionine-dependent methyltransferase n=4
           Tax=Lactobacillales RepID=B4U0G0_STREM
          Length = 256

 Score =  117 bits (294), Expect = 3e-25,   Method: Composition-based stats.
 Identities = 50/247 (20%), Positives = 109/247 (44%), Gaps = 20/247 (8%)

Query: 12  KFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVIL 71
           K  +++     G+L   +++  L  +          +LD G G   TA  +A++ ++V  
Sbjct: 25  KAYKDMLTRPWGKLMYDLIFAQLGPI------AGKTILDFGAGFCITAEALADQ-NEVTA 77

Query: 72  CDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSV 131
            + +  ++  AK+        +++  I  + + +    +   D+I+ H VLE++A     
Sbjct: 78  IEPNPDLL-FAKKQ-------ESIHKIKGSLEALEKLPDQAFDMIICHNVLEYIAPKEHA 129

Query: 132 --LQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGN-FDYVQAGMPKKKKRTLSPDYPRDP 188
             L  +  +L+P G LSL+ +N  G ++H ++  + +D     +  +   +LS    +  
Sbjct: 130 VYLAQMERLLKPKGQLSLIKHNQVGKVLHAVIFEHDYDKALDVLNGQAFESLSFAAGQT- 188

Query: 189 AQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQ-QRDCYEALLELETRYCRQEPYITLGRY 247
             +   L +   ++ G  G+R  +     + + + D  EAL  +E   C Q+PY  +  +
Sbjct: 189 YSIDDLLRKTDLKLQGYRGLRTCYGLQPNEVKAKPDWLEALRTIELAICDQKPYKDMAFF 248

Query: 248 IHVTARK 254
            H+   K
Sbjct: 249 QHLMLIK 255


>UniRef50_A0LNU5 3-demethylubiquinone-9 3-methyltransferase n=1 Tax=Syntrophobacter
           fumaroxidans MPOB RepID=A0LNU5_SYNFM
          Length = 258

 Score =  117 bits (294), Expect = 3e-25,   Method: Composition-based stats.
 Identities = 37/211 (17%), Positives = 72/211 (34%), Gaps = 8/211 (3%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQA---ILWQDLDRVLAEMGPQKLRVLDAGGGEGQ 57
           + +  +     ++     G     LR     + +    R L E+      +LD G G G 
Sbjct: 3   IDNEVYQTYGHEWWSENAGFNVFSLRYCMNPVRYGYFKRKLRELRLPGGTILDVGCGGGL 62

Query: 58  TAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLIL 117
            A + A  G  V   D + + ++ A++ A    +   + +     + +    +   D++ 
Sbjct: 63  LAEEFARDGFAVTGIDPATRSLEAARKHAADTNLE--IDYREGKGEALP-FPDGSFDIVA 119

Query: 118 FHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKK 177
              VLE V D   V+  +   LR GGV      N        ++  + D+        K 
Sbjct: 120 CCDVLEHVDDLGLVIGEVARTLRAGGVFCYDTVNRTWFSKLALIKISQDW--GFTSWSKP 177

Query: 178 RTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
                +    PA++   +   G       G+
Sbjct: 178 NVHVWEKFIKPAELIAVMNRCGLANQELRGI 208


>UniRef50_A6F2N0 SAM-dependent methyltransferase n=1 Tax=Marinobacter algicola DG893
           RepID=A6F2N0_9ALTE
          Length = 204

 Score =  117 bits (294), Expect = 3e-25,   Method: Composition-based stats.
 Identities = 45/198 (22%), Positives = 86/198 (43%), Gaps = 19/198 (9%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           +D  A++++++       Q+R    +Q    +          VL+ G G G TA+  A  
Sbjct: 8   WDKSAQRYAKS-------QVRDEASYQKKLAITQGYFQPNWSVLEFGCGTGSTALVHAPH 60

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV 125
             +++  D+S +M++ A Q A   GV +N++F     + +A       D +L   +L  +
Sbjct: 61  VKEILATDISDKMLEIAAQKARDAGV-ENVRFQQGTLESLALEA-GSFDAVLGLNILHLL 118

Query: 126 ADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYP 185
            +P + +  +  +L+PGGV      ++  L+   MV          +P  +   L+P   
Sbjct: 119 ENPETAIARVHELLKPGGVFV----SSTALVGELMVLWRL-----LIPAMQAMGLAPFVN 169

Query: 186 RDPAQ-VYLWLEEAGWQI 202
           R   Q +   L  AG+ I
Sbjct: 170 RFSRQSLVTMLTNAGFSI 187


>UniRef50_D2QHG7 Methyltransferase type 11 n=1 Tax=Spirosoma linguale DSM 74
           RepID=D2QHG7_9SPHI
          Length = 259

 Score =  117 bits (294), Expect = 3e-25,   Method: Composition-based stats.
 Identities = 43/191 (22%), Positives = 83/191 (43%), Gaps = 20/191 (10%)

Query: 18  YGTTKGQLRQAILWQDLDRVLAEMGPQKL-RVLDAGGGEGQTAIKMAERGHQVILCDLSA 76
           +     Q + A ++   + VL  + PQ   R+LD G G G+   ++AE G ++I  D S 
Sbjct: 8   WNADLYQQKHAFVFHFGEDVLNLLDPQPGERILDLGCGTGELTARIAESGAKIIGLDASL 67

Query: 77  QMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRS--VLQT 134
            MI +A+++        ++ F    A++  +  + P D I  +A L W+ +     VL  
Sbjct: 68  SMISKARESF------PHLSFQEGDARNFGT--DQPFDAIFSNATLHWINETEQPSVLAA 119

Query: 135 LWSVLRPGGVLSLMFYNAHGLLMH--NMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVY 192
           ++  L+PGG   +      G +    N +A   + +    P      ++P++     +  
Sbjct: 120 VFKALKPGGRF-VAELGGRGNVARILNALAKALNELGMLQP------VNPNFFPSVGEYT 172

Query: 193 LWLEEAGWQIM 203
             LE  G+ + 
Sbjct: 173 TLLETVGFFVT 183


>UniRef50_B9XT55 Methyltransferase type 11 n=1 Tax=bacterium Ellin514
           RepID=B9XT55_9BACT
          Length = 291

 Score =  117 bits (294), Expect = 3e-25,   Method: Composition-based stats.
 Identities = 50/226 (22%), Positives = 98/226 (43%), Gaps = 36/226 (15%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
            F+ +A +F R+ YG  +        WQ   ++L  + P  L V D G GEG  +  +A 
Sbjct: 97  YFNQVAGRFDRS-YGPGRS-------WQAFGQLLLRILP-PLTVADLGSGEGLLSELLAL 147

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
           +  +VI  D S ++I+     A+  G+  N++F     ++        VDL++    L  
Sbjct: 148 KAKKVIAVDNSERIIEFGANKAKKNGLK-NLEFRLGDLEN-PPIDPHSVDLVILSQALHH 205

Query: 125 VADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDY 184
            A+P   +Q+ + +L+PGG + ++    H     + + G+             R L   +
Sbjct: 206 AAEPAKAIQSAYKILKPGGHIWILDLLKHNFEKAHELYGD-------------RWLG--F 250

Query: 185 PRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLE 230
           P   + ++ WLE AG++ +  +        +    +Q   ++ +L 
Sbjct: 251 P--ESDMHHWLEAAGFKKIEIS--------VVASEEQPPHFQTILA 286


>UniRef50_Q88SI6 Menaquinone biosynthesis methyltransferase ubiE n=6
           Tax=Lactobacillales RepID=UBIE_LACPL
          Length = 237

 Score =  117 bits (293), Expect = 4e-25,   Method: Composition-based stats.
 Identities = 44/223 (19%), Positives = 76/223 (34%), Gaps = 30/223 (13%)

Query: 1   MQDRN-------FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGG 53
           M +R        FD IA  + R     + G  R    W+        +      VLD   
Sbjct: 1   MANRYLHNVQGLFDTIAPNYDRMNNIISLGTHRH---WRKQTMAQIHLA-SNAHVLDLCC 56

Query: 54  GEGQTAIKMA---ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLE 110
           G G   I +A   +   +VI  D SA M+  A+Q    + V+D +      A  +    +
Sbjct: 57  GTGDWTIALAKELQAPGEVIGLDFSAPMLKLAQQKVTQQQVADRVWLRRGNAMHLP-FKD 115

Query: 111 TPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQA 170
              DL+     L  + D    L  ++ VL+PG  L  +  +        ++   + +   
Sbjct: 116 NTFDLVTIGFGLRNLPDKAQALTEIYRVLKPGARLVCLETSQPD---QPLIKPVWQWYFT 172

Query: 171 GMPKKKKRTLSPDY------------PRDPAQVYLWLEEAGWQ 201
            +     R  +  Y                 Q+    ++AG+Q
Sbjct: 173 KVVPLFGRLFAHQYQEYSYLQETTRHFASYQQLATMFQQAGFQ 215


>UniRef50_Q5VMJ1 Putative dihydroxypolyprenylbenzoate methyltransferase n=2
           Tax=Magnoliophyta RepID=Q5VMJ1_ORYSJ
          Length = 221

 Score =  117 bits (293), Expect = 4e-25,   Method: Composition-based stats.
 Identities = 34/164 (20%), Positives = 66/164 (40%), Gaps = 5/164 (3%)

Query: 44  QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQ 103
           + L+V+D G G G  +  +A  G  V   D   + I  A+  A +   + ++++    A+
Sbjct: 28  EGLKVIDVGCGGGILSEPLARMGATVTGIDAVDKNIKIARVHAASDPSTASIEYFCTTAE 87

Query: 104 DVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAG 163
           D+        D ++   V+E VA+P    ++L ++  P G   +   N         +  
Sbjct: 88  DLVKE-NKQFDAVISLEVIEHVANPSGFCESLSALTVPNGATVISTINRSMRAYATAIVA 146

Query: 164 NFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTG 207
             +Y+   +PK   +         P ++ L LE A   +    G
Sbjct: 147 A-EYILNWLPKGTHQW---SKLVTPEELVLILERASISVQEMAG 186


>UniRef50_Q21PF3 Methyltransferase type 11 n=1 Tax=Saccharophagus degradans 2-40
           RepID=Q21PF3_SACD2
          Length = 277

 Score =  117 bits (293), Expect = 4e-25,   Method: Composition-based stats.
 Identities = 37/164 (22%), Positives = 65/164 (39%), Gaps = 5/164 (3%)

Query: 48  VLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVAS 107
           +LD G G G    ++   G+Q +  D SA ++  A +  E+    D         Q +  
Sbjct: 57  ILDLGCGAGPFVSELLRHGYQCVATDYSADILANAVKRIESIPC-DRTPLAQSDCQFIPF 115

Query: 108 HLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMF---YNAHGLLMHNMVAGN 164
             +   D ++   V+ +V D    L  +  +L P G L + F   YN       N + G 
Sbjct: 116 ASQA-FDAVVCLGVISYVPDRSKALGEMSRILAPDGQLLITFRNYYNPVVFEPLNWLKGL 174

Query: 165 FDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
           F  V   +  +      P     P  +   LE+AG +++ + G+
Sbjct: 175 FGKVIPSIHAEHTGEFVPGAFLKPQAIKCLLEQAGLEVVEQYGI 218


>UniRef50_Q2CBK3 Methyltransferase, UbiE/COQ5 family protein n=1 Tax=Oceanicola
           granulosus HTCC2516 RepID=Q2CBK3_9RHOB
          Length = 206

 Score =  116 bits (292), Expect = 5e-25,   Method: Composition-based stats.
 Identities = 44/204 (21%), Positives = 81/204 (39%), Gaps = 20/204 (9%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
           R +D IA +++R            A     L +    + P    VL+   G G TA+  A
Sbjct: 6   RFWDKIARRYARRPVDDP------AAYEAKLAKTAEYLTPDS-EVLELACGTGTTALWHA 58

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
            +   V+  D SA M++ A+  A  +GV +N+ F   A + +        D+++ H++L 
Sbjct: 59  PKVRHVLATDFSAPMLEIARARAAEQGV-ENVTFRQTAIEAL-EVAPASYDMVMAHSILH 116

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPD 183
            V D + V     + L+PGG            +   +  G    ++  +       L P 
Sbjct: 117 LVDDRQVVYALARAALKPGGHF----------VSSTVCLGRLSPMRLILVPGHAIGLLPQ 166

Query: 184 -YPRDPAQVYLWLEEAGWQIMGKT 206
                   +   +E AG++I+ + 
Sbjct: 167 VRFLSADGLAAEIEAAGFEIVHRY 190


>UniRef50_A4S2A7 Predicted protein n=1 Tax=Ostreococcus lucimarinus CCE9901
           RepID=A4S2A7_OSTLU
          Length = 218

 Score =  116 bits (292), Expect = 5e-25,   Method: Composition-based stats.
 Identities = 36/166 (21%), Positives = 68/166 (40%), Gaps = 6/166 (3%)

Query: 44  QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAE-AKGVSDNMQFIHCAA 102
           + L++LD G G G  A  +A  G QV   D  A  I  A+  AE    +  N+++    A
Sbjct: 31  RGLKILDVGCGGGILAESLARLGAQVTAIDAGAANIAIARAHAELDPDLVKNLKYEAVTA 90

Query: 103 QDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVA 162
           +++    ET  D +    V+E V DP    +++  +++P G L +   N         + 
Sbjct: 91  EELVERGET-FDCVTSLEVIEHVTDPLEFTKSIAKLVKPKGALFVSTINRTARSFAFAIL 149

Query: 163 GNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
              + V   +P    +         P ++ +    A  +++   G+
Sbjct: 150 AA-ERVLGLVPPGTHQF---SKFLTPGEIAMMAGHANCEMVELAGM 191


>UniRef50_D1Z1A4 Putative uncharacterized protein n=1 Tax=Methanocella paludicola
           SANAE RepID=D1Z1A4_METPS
          Length = 267

 Score =  116 bits (292), Expect = 5e-25,   Method: Composition-based stats.
 Identities = 38/136 (27%), Positives = 68/136 (50%), Gaps = 2/136 (1%)

Query: 11  EKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLR-VLDAGGGEGQTAIKMAERGHQV 69
           EKFS      + G  +        ++++ E G +    VLD G G G+T+  +A  G +V
Sbjct: 11  EKFSYLDLLASLGSAKHIGGRGATEKLIGEAGIKPGSYVLDVGCGMGKTSCMLAGMGCRV 70

Query: 70  ILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPR 129
           +  D+  +MI  +K  A   GVSD   F+ C A+ +    ET  D ++  +V  ++ D  
Sbjct: 71  VGVDIMPRMIKESKARAWQTGVSDKTTFVECDARSLPFEPET-FDAVVVESVTVFMDDVE 129

Query: 130 SVLQTLWSVLRPGGVL 145
             ++  + V++PGG++
Sbjct: 130 RAIKGYYRVVKPGGIV 145


>UniRef50_A4X7A0 Methyltransferase type 11 n=9 Tax=Bacteria RepID=A4X7A0_SALTO
          Length = 260

 Score =  116 bits (292), Expect = 5e-25,   Method: Composition-based stats.
 Identities = 41/204 (20%), Positives = 73/204 (35%), Gaps = 12/204 (5%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M+  ++D+ A  +S                ++    +      Q  RVLDAG G G  + 
Sbjct: 29  MRADHYDNFARSYSIENESGF-----YNAYYERPAMLTLAGDVQGRRVLDAGCGSGPLSE 83

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
            +  +G  V   D S  M++ A+       + ++               +   D ++   
Sbjct: 84  ALRAKGAIVTGFDSSPAMVELARTR-----LGEDADLQVADISLPLPFADGAFDDVVVSL 138

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQ--AGMPKKKKR 178
           VL ++ D  + L  L  VL+PGG L L   +   L   +  A  F   Q         + 
Sbjct: 139 VLHYLQDWGAALSELRRVLKPGGRLLLSVNHPRILESRDPNADYFSVTQHSGEYTFGDEH 198

Query: 179 TLSPDYPRDPAQVYLWLEEAGWQI 202
            +   + R    +     EAG++I
Sbjct: 199 VVLTFWHRPLHAMTDAFTEAGFRI 222


>UniRef50_A0ZM88 3-demethylubiquinone-9 3-methyltransferase n=1 Tax=Nodularia
           spumigena CCY9414 RepID=A0ZM88_NODSP
          Length = 252

 Score =  116 bits (292), Expect = 5e-25,   Method: Composition-based stats.
 Identities = 37/167 (22%), Positives = 65/167 (38%), Gaps = 13/167 (7%)

Query: 44  QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQ 103
           Q ++VLD G G G  +  +A++   V   DLS + I  A+  A    +  N+ +    A+
Sbjct: 45  QGIKVLDIGCGGGLASETLAKQEACVTGIDLSLESIKVAQAHARKNHL--NIDYYWGFAE 102

Query: 104 DVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNA---HGLLMHNM 160
           ++        D +L   VLE V D + V+     VL+  G+      N      L+M  +
Sbjct: 103 NLP-FAAKKFDAVLCCDVLEHVTDWQKVISEAHRVLKTNGLFFFDTINRSFKSKLIMIWL 161

Query: 161 VAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTG 207
           +      +  G+    K          P ++   +E  G   +   G
Sbjct: 162 LEDIVKQIPPGLHDWHK-------FIKPEELTYTMENNGLNNVVIKG 201


>UniRef50_C7PC96 Methyltransferase type 11 n=1 Tax=Chitinophaga pinensis DSM 2588
           RepID=C7PC96_CHIPD
          Length = 252

 Score =  116 bits (292), Expect = 5e-25,   Method: Composition-based stats.
 Identities = 39/191 (20%), Positives = 65/191 (34%), Gaps = 21/191 (10%)

Query: 48  VLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVAS 107
           +LD G G G+   ++AE G +V   D S  MI  AK+          + F    A   + 
Sbjct: 34  ILDLGCGTGELTAQVAESGAKVTGLDSSPAMIASAKEHF------PQVTFQVADATSFS- 86

Query: 108 HLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDY 167
            L    D +  +A L W+      L  +   L+PGG   L       +   + + G  + 
Sbjct: 87  -LPEQFDAVFSNATLHWIRQQEKALDRIHQHLKPGGRFVLEMGGKGNV---DDITGALEK 142

Query: 168 VQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEA 227
             A    +        Y     +    LEE G++I           Y   + +  D    
Sbjct: 143 AMA---DRGYTYKPFWYFPSVGEYTSLLEEYGFRINQVL-------YFDRETELADPENG 192

Query: 228 LLELETRYCRQ 238
           ++E    +   
Sbjct: 193 IVEWLQMFGSH 203


>UniRef50_A4X9U1 Methyltransferase type 11 n=5 Tax=Actinomycetales
           RepID=A4X9U1_SALTO
          Length = 256

 Score =  116 bits (292), Expect = 5e-25,   Method: Composition-based stats.
 Identities = 71/234 (30%), Positives = 103/234 (44%), Gaps = 7/234 (2%)

Query: 26  RQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQA 85
           R A++W  L   L       L VLD GGG G  A+ +A+ GH+V + D +   +    + 
Sbjct: 23  RTAVIWSVLRAELDRRADTDLTVLDVGGGTGGFAVPLAQAGHRVTVVDANPDALAALTRR 82

Query: 86  AEAKGVSDNMQFIHCAAQDVASHLE-TPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGV 144
           A   GV+D ++ +      +A  +E   VDL+L HAVLE V DP +V+  L   LRPGG 
Sbjct: 83  AADAGVADRVRAVQGDGDALAGLVEPASVDLVLCHAVLEVVDDPVAVVAALAGALRPGGA 142

Query: 145 LSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPR----DPAQVYLWLEEAGW 200
            S++       ++   + G  D V   +      T  P           +    L  AG 
Sbjct: 143 ASVLVAGRAAAVLSRAMTGQLD-VAGLLAADSAGTAGPRDTLRRRFAADEAAALLAAAGL 201

Query: 201 QIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPYITLGRYIHVTARK 254
           ++    GVRV  D L           ALLELE     Q P+  L   +H+ AR+
Sbjct: 202 EVEELHGVRVLTDLLPAA-VGDGQPAALLELELALAAQPPWRDLAAQLHLFARR 254


>UniRef50_D1Z1F5 Putative uncharacterized protein n=1 Tax=Methanocella paludicola
           SANAE RepID=D1Z1F5_METPS
          Length = 213

 Score =  116 bits (292), Expect = 6e-25,   Method: Composition-based stats.
 Identities = 44/209 (21%), Positives = 84/209 (40%), Gaps = 11/209 (5%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           ++ R+ DD   +F+     T +G + + +  ++L  +LA         ++ G G G    
Sbjct: 2   LEHRDKDDYWGRFADTYDDTLEGMIGRDV-RRNLAAILAS-EHDPGNAVEFGCGTGYFTR 59

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
            +A     V+  D+S  M+D A+          N+ F    ++       +  D  L   
Sbjct: 60  VIAGNAKHVLATDMSPGMVDAARSNLRDL---HNVSFQVQDSES-PGLPSSTFDTALMAN 115

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
           +L  + DP   L+  + VL+PGG+L ++ Y   G+        +F +        KK   
Sbjct: 116 MLHTLDDPARALKECFRVLKPGGMLLIINYTEDGMGRVQRTLLSFQFHLRFGFAPKKSW- 174

Query: 181 SPDYPRDPAQVYLWLEEAGWQIMGKTGVR 209
               P    ++  +L +A ++I     VR
Sbjct: 175 ----PLTSEKLQSFLGQARFRIERMDLVR 199


>UniRef50_Q01S22 Methyltransferase type 11 n=1 Tax=Candidatus Solibacter usitatus
           Ellin6076 RepID=Q01S22_SOLUE
          Length = 243

 Score =  116 bits (292), Expect = 6e-25,   Method: Composition-based stats.
 Identities = 56/253 (22%), Positives = 100/253 (39%), Gaps = 20/253 (7%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           FD +A ++      T  G+ ++ ++W+D++ +         R+LD G G G+ A   A R
Sbjct: 7   FDGMAARYDAMWTTTPVGRAQRDLVWRDVEPLFE----AGERILDIGCGTGEDAAHFAAR 62

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFH-AVLEW 124
           G  V   D S  M+  A+    A+GV+  +    C A+DVA  +E   D  + +   L  
Sbjct: 63  GVAVRAIDASPAMVSAAR----ARGVAAEV----CRAEDVA-RIEETFDGAISNFGALNC 113

Query: 125 VADPRSVLQTLWSVLRPGGVLSLMFYNA--HGLLMHNMVAGNFDYVQAGMPKKKKRTLSP 182
           V D  +V ++L +V+ PGG  ++           +H  V   F         +    L+ 
Sbjct: 114 VEDLSAVAESLAAVVHPGGRAAICLLGRCCVWETLHYGVRLQFGKAFRRWTGRVAAPLAA 173

Query: 183 DYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPYI 242
            YP    +V       G+ +   TG+ +       K         L   +    R     
Sbjct: 174 WYP-TAGEVRAAF-AYGFALQSWTGIGLLVPPSYVKLPGAMVPV-LAACDRVLARLPLLR 230

Query: 243 TLGRY-IHVTARK 254
            +  + +++  RK
Sbjct: 231 AMADHRLYILVRK 243


>UniRef50_C8Q6G5 Methyltransferase type 11 n=1 Tax=Pantoea sp. At-9b
           RepID=C8Q6G5_9ENTR
          Length = 287

 Score =  116 bits (291), Expect = 7e-25,   Method: Composition-based stats.
 Identities = 51/255 (20%), Positives = 100/255 (39%), Gaps = 20/255 (7%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
           N D  A  +    +  T  +    +  Q LD    +    +  VLD   G G+ A   AE
Sbjct: 22  NKDGAAWHY----WHATLERWYGELTRQILDSAFIQ---PRQHVLDIAAGAGEPAFSAAE 74

Query: 65  R----GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
           R    G+ V+  D+S  +I  A+QAA  +G++     +     +V S  +   D ++   
Sbjct: 75  RVGLEGY-VLATDISDGIIALARQAASDRGLTQVATRVMDG--EVLSLPDASFDAVICRL 131

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
            L ++  P + L+    VL+PGG +++  ++         +  +    +A +P       
Sbjct: 132 GLMYMPHPGAALREWHRVLKPGGHVAVAVFSTADRNSWGAIPASIIRRRAQLPPPVAGQP 191

Query: 181 SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFH------DYLREKHQQRDCYEALLELETR 234
            P     P  +     +AG+  +  + V V H      +Y+R   +    + A++     
Sbjct: 192 GPFSLGYPEVLQRLFIQAGFSNLSISTVLVPHRAASATEYVRVAREAFGGFNAMMASLPC 251

Query: 235 YCRQEPYITLGRYIH 249
             R+  +  +   +H
Sbjct: 252 TERESAWHEIETSLH 266


>UniRef50_D0LMD2 Methyltransferase type 11 n=1 Tax=Haliangium ochraceum DSM 14365
           RepID=D0LMD2_HALO1
          Length = 415

 Score =  116 bits (291), Expect = 7e-25,   Method: Composition-based stats.
 Identities = 47/209 (22%), Positives = 84/209 (40%), Gaps = 18/209 (8%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
           R FD IA     ++Y      L  ++  + L++   + G     VL+ G G G  +   A
Sbjct: 13  RWFDAIA-----SVYDEGLSALLLSLHQKMLEQARLQTGE---TVLNLGCGTGMDSFLTA 64

Query: 64  ERGHQ---VILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
               +   V+  D++ +M+  A + A ++G+ DN+ F    A+ +        D I+   
Sbjct: 65  PLIGEEGSVVGIDIAPEMVRLANEKAGSRGL-DNVTFQVMDAEKLKFKA-NHFDAIISQW 122

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
            L +  + R  L+  + VL+PGG  +L            MV   F  V   +P       
Sbjct: 123 ALMFFPNDRGALREAYRVLKPGGRFALSVVGRPENSPFLMVP--FRVVAKTLPGVAISEG 180

Query: 181 SPDYPRDPAQ--VYLWLEEAGWQIMGKTG 207
            P   R   +  +   L +AG+ +   +G
Sbjct: 181 GPPTFRFAREGALEAALSQAGF-VSTWSG 208


>UniRef50_Q8R7K7 SAM-dependent methyltransferases n=7 Tax=Thermoanaerobacterales
           RepID=Q8R7K7_THETN
          Length = 222

 Score =  116 bits (291), Expect = 7e-25,   Method: Composition-based stats.
 Identities = 31/125 (24%), Positives = 59/125 (47%), Gaps = 1/125 (0%)

Query: 30  LWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAK 89
           + +D+   L  +G  K   LD G G G+ A+ +AE G+ V+  D S + + RA++     
Sbjct: 45  MERDIQDALEMLGRGKGFALDIGTGRGRMALGLAEYGYDVVSLDESLEALKRAREFIRES 104

Query: 90  GVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMF 149
           GV + +  +      +   L+   D++  +  L  + D + VL  +  V + GG + +  
Sbjct: 105 GVEEKVLLMVGDGHSLP-FLDETFDVVATYNALHHMRDYKRVLDEMVRVCKKGGKIVISE 163

Query: 150 YNAHG 154
            N +G
Sbjct: 164 LNEYG 168


>UniRef50_B4WI79 Methyltransferase domain family n=1 Tax=Synechococcus sp. PCC 7335
           RepID=B4WI79_9SYNE
          Length = 426

 Score =  116 bits (291), Expect = 8e-25,   Method: Composition-based stats.
 Identities = 49/229 (21%), Positives = 77/229 (33%), Gaps = 18/229 (7%)

Query: 44  QKLRVLDAGGGEGQTAIKMAERG--HQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCA 101
             +R+LDAG G G +   +       +V+  DLSA  I  AK+  +  G +D   F + +
Sbjct: 78  NSVRILDAGCGTGVSTEYLVHLNPEAEVVGIDLSAGAIAVAKERCQRSG-ADRASFYNTS 136

Query: 102 AQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMV 161
             DV   +    DLI    VL  + DP   +Q L   L+PGG+  +  Y   G     + 
Sbjct: 137 IYDV-EQIPGKFDLINCVGVLHHLPDPIRGIQALAKKLKPGGIFHIFVYAELGRWEIQLT 195

Query: 162 AGNFDYVQAGMPKKKKRTLSPDY----PRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLRE 217
                 +Q       K  ++                  EE  W +  +     F D    
Sbjct: 196 QEAIALLQGDQRGDYKNGVAIGRNLFSALPKENRLRQREETRWALENQRD-ECFADMYVH 254

Query: 218 KHQQRDCYEALLELETRYCRQ------EPYITLGRYIHVTARKPQSKDK 260
             +     + L +L               Y  L R   +    P   D+
Sbjct: 255 PQEIDYNVKTLFDLIDASGLDFVGFSNPQYWDLSR---LIGSAPDLMDR 300


>UniRef50_B8FPB3 Methyltransferase type 11 n=4 Tax=Clostridiales RepID=B8FPB3_DESHD
          Length = 209

 Score =  116 bits (291), Expect = 8e-25,   Method: Composition-based stats.
 Identities = 40/201 (19%), Positives = 86/201 (42%), Gaps = 19/201 (9%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIK 61
             + +D  +  +   I    K        ++++  +++E+    +RVL+   G G  A+ 
Sbjct: 4   NKKFWDRYSGLYDFEINRFNK------AAYEEMYSLMSEVLRADMRVLEVATGTGLMALG 57

Query: 62  MAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
           +A+   QV   D S +MI+ AK+         N++F    A  ++   +   D ++    
Sbjct: 58  IAKFVRQVEATDFSPKMIETAKKKIA----PANVRFSLEDATALSFAND-SFDAVIISNA 112

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLS 181
           L  + DP + L ++  VL+P G+L    + AHG L ++    N   ++    +   +   
Sbjct: 113 LHIMPDPEATLASIRRVLKPDGLLIAPTF-AHGHLKNSTWNLNARILKLIGFETYSKW-- 169

Query: 182 PDYPRDPAQVYLWLEEAGWQI 202
                 P +   ++E+ G+ +
Sbjct: 170 -----TPEEYTGFIEKNGFSV 185


>UniRef50_Q67LE6 Menaquinone biosynthesis methyltransferase ubiE n=1
           Tax=Symbiobacterium thermophilum RepID=UBIE_SYMTH
          Length = 251

 Score =  116 bits (291), Expect = 8e-25,   Method: Composition-based stats.
 Identities = 43/214 (20%), Positives = 71/214 (33%), Gaps = 26/214 (12%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           FD IAE +       + GQ  +   W           P    +LD   G G   +  A +
Sbjct: 21  FDKIAENYDAMNQVMSAGQWEK---WHREFVAQTHFRPGDH-ILDVACGTGDLTLLDAAQ 76

Query: 66  GH---QVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
                +VI  D+S  M++  ++   A    D +      A D+    +   D +     +
Sbjct: 77  VAPDGKVIGVDISEGMLEVGRRRVAASPYKDLITLQLGNAMDLP-FPDNTFDGVTMGWAM 135

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMP--------- 173
             VA     L  ++ VL+PGG    +  +        +  G F Y +  +P         
Sbjct: 136 RNVASIPRTLSEIYRVLKPGGRFICLEASK--PFSRFIRFGFFVYWKTFLPLIDWFVVKA 193

Query: 174 -------KKKKRTLSPDYPRDPAQVYLWLEEAGW 200
                       + S D    P Q+     EAG+
Sbjct: 194 GRQAKVRPYTYLSRSLDNYPFPDQLEELFREAGF 227


>UniRef50_Q9RYC4 Methyltransferase, putative n=2 Tax=Deinococcus RepID=Q9RYC4_DEIRA
          Length = 269

 Score =  116 bits (291), Expect = 8e-25,   Method: Composition-based stats.
 Identities = 39/149 (26%), Positives = 65/149 (43%), Gaps = 14/149 (9%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
           R FD IA  +    +          +    L    A   P   RVLD   G G  A+ +A
Sbjct: 13  RQFDRIAADYDALGF----------LTQAALALAAALDVPPTGRVLDVATGTGTVALTLA 62

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
            +  +V+  D++  MI++A+Q A  +    N+QF+   A  +    +   D+++  A L 
Sbjct: 63  PKVAEVMGTDIAPAMIEQARQRAAGR---SNVQFVLAEATALT-FADQSFDVVVCGAGLF 118

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNA 152
           +V D  + L+    VLRPGG +    +  
Sbjct: 119 FVPDMVAALREWRRVLRPGGEVVFSAFGR 147


>UniRef50_A1TE65 Methyltransferase type 11 n=1 Tax=Mycobacterium vanbaalenii PYR-1
           RepID=A1TE65_MYCVP
          Length = 280

 Score =  116 bits (290), Expect = 9e-25,   Method: Composition-based stats.
 Identities = 40/181 (22%), Positives = 73/181 (40%), Gaps = 8/181 (4%)

Query: 34  LDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER-GHQ--VILCDLSAQMIDRAKQAAEAKG 90
           +D V A  GP++ ++LD G G G T + +AER G        D+S  MI  A+  A  + 
Sbjct: 40  VDSVAAAAGPRE-QILDLGCGTGATTLALAERLGAHGGCTGIDISEPMIHAARTRARDRN 98

Query: 91  VSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFY 150
           +   ++F+   AQ          D+++    + +  DP +  + L    RPGG L+ + +
Sbjct: 99  LP--VEFVVGDAQSFP-FQPNTFDVMVSRFGVMFFDDPTTAFRNLRRATRPGGRLTFVCW 155

Query: 151 -NAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVR 209
            +       +        + + +      +  P    D  + +  L   GW  +    V 
Sbjct: 156 RDPTDNPFMSTAERAAAQLLSDLKPGIAGSPGPFAFADAHRTHSILRAGGWTAVDIRPVD 215

Query: 210 V 210
           V
Sbjct: 216 V 216


>UniRef50_A8ICE1 Hexaprenyldihydroxybenzoate methyltransferase (Fragment) n=1
           Tax=Chlamydomonas reinhardtii RepID=A8ICE1_CHLRE
          Length = 263

 Score =  116 bits (290), Expect = 9e-25,   Method: Composition-based stats.
 Identities = 45/178 (25%), Positives = 78/178 (43%), Gaps = 11/178 (6%)

Query: 38  LAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAK-GVSDNMQ 96
           +  M P  LRVLD G G G  +  +A  G QV   D++ + ++ A+  A A   V++ ++
Sbjct: 1   MPHMRPTGLRVLDVGCGGGILSESLARLGAQVTGIDVTRENVEAARLHAAADPAVAERVR 60

Query: 97  FIHCAAQDVASHLETP----VDLILFHAVLEWVADPRSVLQTLWSVL--RPGGVLSLMFY 150
           +   + +D+A+          D +L   VLE VA P + +  L S+L  RPG  + +   
Sbjct: 61  YEVISVEDLAAAAAGGTTGLYDAVLASEVLEHVARPHAFVGVLASLLAPRPGASVIISTL 120

Query: 151 NAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
           N        +     +YV   +P       S      P ++ +  + AG Q+    G+
Sbjct: 121 NRT-PAAWAVAIAGAEYVTGVVPVGTH---SWKKFITPEELAIMGDAAGLQVWHAAGM 174


>UniRef50_Q65P11 Putative uncharacterized protein n=4 Tax=Bacilli RepID=Q65P11_BACLD
          Length = 257

 Score =  116 bits (290), Expect = 9e-25,   Method: Composition-based stats.
 Identities = 33/149 (22%), Positives = 68/149 (45%), Gaps = 6/149 (4%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
           + ++  A+ ++ N   T +G + + +    +   L E   +  +VLDAG GEG  +  +A
Sbjct: 12  QRWNRFADSYAANH--TEQGDIHKEVFLNPVIFSLIE-TVKNQKVLDAGCGEGYLSRMLA 68

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
            R   V   D S +M++ AK+         ++ + H   +D+    E   D+I+ + V++
Sbjct: 69  AREAVVTAVDYSTRMLEIAKERTPD---GLHIHYRHGNCEDLHFLDEQSFDIIISNMVIQ 125

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNA 152
            +A+     Q +  +L+ GG       + 
Sbjct: 126 DLANDEKAFQEMHRLLKDGGCFIFSILHP 154


>UniRef50_B8G0Y2 Methyltransferase type 11 n=1 Tax=Desulfitobacterium hafniense
           DCB-2 RepID=B8G0Y2_DESHD
          Length = 257

 Score =  116 bits (290), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 38/147 (25%), Positives = 62/147 (42%), Gaps = 7/147 (4%)

Query: 10  AEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQV 69
           A+ ++  I     G+L +   W DL  ++        +VLD G G G  A+ M   G  V
Sbjct: 17  ADGYNAIIQNEFSGELSKK--WSDL--LIGNAPCPAGKVLDVGTGPGFFALLMGSMGWDV 72

Query: 70  ILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPR 129
              D S +MI+ A   A+  G+  + +F    +  +    +   D I+   V   + +P 
Sbjct: 73  HGIDCSEKMIETAVANAQKAGI--DAEFSVMDSHSL-DFPDNTFDYIVGRNVTWILYEPE 129

Query: 130 SVLQTLWSVLRPGGVLSLMFYNAHGLL 156
              +    VL+PGG L  +  N H  L
Sbjct: 130 KAFKEWLRVLKPGGRLLYLDGNWHYTL 156


>UniRef50_A3XJF1 Putative uncharacterized protein n=1 Tax=Leeuwenhoekiella
           blandensis MED217 RepID=A3XJF1_9FLAO
          Length = 249

 Score =  116 bits (290), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 50/231 (21%), Positives = 100/231 (43%), Gaps = 35/231 (15%)

Query: 17  IYGTTKGQLRQAILWQDLDRVLAEMGPQK-LRVLDAGGGEGQTAIKMAERGHQVILCDLS 75
           ++     + +   ++     +++ + PQK  R+LD G G G+    +AE G Q++  D S
Sbjct: 1   MWEADLYREKHGFVFNYGKDLISMLNPQKDERILDLGCGTGELTAAIAESGAQLVGIDAS 60

Query: 76  AQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTL 135
            +MID AK   +      N++FI    +  +   +   D I  +A L W+ +P + +  +
Sbjct: 61  QEMIDAAKAQFK------NIEFITARGE--SFIDQERYDAIFSNATLHWILNPEAAISAM 112

Query: 136 WSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPK--------KKKRTLSPDYPRD 187
           +S L+ GG L L              AGN D +   + +        K+ RT++  +P+ 
Sbjct: 113 YSNLKIGGRLLLEMGG----------AGNIDTIIKALSRVLEEKGYFKQSRTINWYFPKL 162

Query: 188 PAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQ 238
               Y +LE++G+Q+        F        + +D    +++    + + 
Sbjct: 163 GTYCY-FLEKSGFQVT-------FAHLYERPTKLKDPETGIIDWLKMFAKH 205


>UniRef50_A4EUG7 Methyltransferase, UbiE/COQ5 family protein n=5 Tax=Rhodobacterales
           RepID=A4EUG7_9RHOB
          Length = 211

 Score =  116 bits (290), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 46/204 (22%), Positives = 94/204 (46%), Gaps = 19/204 (9%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQ-DLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
           + +D+IA K++++        +R    ++  L R  + + P   RVL+ G G   TAI++
Sbjct: 6   KFWDNIAPKYAKS-------SIRDEESYRYALGRTRSYLKPND-RVLELGCGTASTAIEL 57

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
           A+     +  D+S  M+   +Q A+  G +DN+  +H  A+D+A   +   D +L H +L
Sbjct: 58  AKGVESFVATDISDGMLAVGRQRAQEAG-ADNLTLLHRPAEDLA---DGEFDAVLAHNLL 113

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSP 182
             + +   VL+ + + L  GG+    F +    L   +    +   +  +P  K    +P
Sbjct: 114 HLIPNLEEVLRNVAAKLPTGGL----FISKTPCLGEQVGTWKYYMFKVAIPLMKLVGKAP 169

Query: 183 DY--PRDPAQVYLWLEEAGWQIMG 204
            +        +   ++ AG++I+ 
Sbjct: 170 SFVDFTRMQDLEAAVQAAGFEIIE 193


>UniRef50_Q0S6F7 3-demethylubiquinone-9 3-O-methyltransferase n=3
           Tax=Actinomycetales RepID=Q0S6F7_RHOSR
          Length = 279

 Score =  116 bits (290), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 41/205 (20%), Positives = 74/205 (36%), Gaps = 15/205 (7%)

Query: 44  QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQ 103
           + LR LD G G G  A +    G +V   D S   +D A++ A   G + ++++   + +
Sbjct: 53  RGLRALDVGSGGGFLAEEFTRIGFRVTGIDPSPVSVDTARRHA--AGSALDIEYRIGSGE 110

Query: 104 DVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAG 163
            +    +   D+     VLE V+D   V+     VL+PGG+      N         +  
Sbjct: 111 HLPV-PDATFDVAYCCDVLEHVSDLDGVIAETSRVLKPGGLYLFDTINRTFASKLVAIKI 169

Query: 164 NFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRD 223
             ++    M               PA++   +E  G ++    G+            +  
Sbjct: 170 MQEWRMTRMFDTPIH--DWSMCIRPAELAPIMERHGLRLGEIVGLG----------PRSK 217

Query: 224 CYEALLELETRYCRQEPYITLGRYI 248
               LL+L      +  Y  L R +
Sbjct: 218 NPLRLLDLARAGGTRLSYGELSRRL 242


>UniRef50_C5FG45 Crg1p n=1 Tax=Microsporum canis CBS 113480 RepID=C5FG45_NANOT
          Length = 294

 Score =  115 bits (289), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 41/165 (24%), Positives = 70/165 (42%), Gaps = 9/165 (5%)

Query: 10  AEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQV 69
           +  FS   Y + + +  Q +     D V +         LD G G G  +  ++ R  +V
Sbjct: 6   SSNFSYTAYASFRPEYPQKL----YDMVFSYHQGAYNTCLDLGCGHGLVSRALSPRFKKV 61

Query: 70  ILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPR 129
              D SA MI++AK     +    N++F+  AA+ +    +  VDL++      W   P 
Sbjct: 62  YGIDPSAGMIEQAKNMTTEQ----NVEFVQAAAESLPFIEDKSVDLVVAGVAAHWFNYPP 117

Query: 130 SVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPK 174
            +   L  V++PGG L+   Y+ H L+ +       D    G+ K
Sbjct: 118 -LFAELQRVMKPGGTLAFWGYSDHYLVDYPKATAVLDKYAYGLDK 161


>UniRef50_P08442 Uncharacterized protein syc1184_c n=29 Tax=Cyanobacteria
           RepID=Y1184_SYNP6
          Length = 417

 Score =  115 bits (289), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 3/126 (2%)

Query: 47  RVLDAGGGEGQTAIKMAERG--HQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQD 104
           R+LDAG G G +   +A      ++   D+SA  +  A++  +  GV+D + F   +  D
Sbjct: 74  RILDAGCGTGVSTDYLAHLNPSAEITAIDISAGTLAVAQERCQRSGVADRIHFQQLSLYD 133

Query: 105 VASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGN 164
           VA  L    D I    VL  + DP   L  L S L PGG+L +  Y   G      +   
Sbjct: 134 VA-QLPGEFDQINCVGVLHHLEDPDRGLAALASKLAPGGILHIFVYAEIGRAEIRQMQEA 192

Query: 165 FDYVQA 170
              +Q 
Sbjct: 193 IALLQG 198


>UniRef50_D2UX54 Predicted protein (Fragment) n=1 Tax=Naegleria gruberi
           RepID=D2UX54_NAEGR
          Length = 252

 Score =  115 bits (289), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 38/182 (20%), Positives = 78/182 (42%), Gaps = 9/182 (4%)

Query: 44  QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQ 103
           + L +LD G G G  +  +A  G  V   D S   I+ A+    +    +N+ +IH   +
Sbjct: 65  KGLNILDVGCGGGLVSECLARLGANVTGLDASLDNINIARTHNTSL---NNLNYIHSTVE 121

Query: 104 DVASHLETP-VDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVA 162
           ++  + E+   D I+   V+E VA  +S +  L  +L+P G L L   N         + 
Sbjct: 122 NLLYNNESTKFDCIVSVEVIEHVAHAQSFVHNLSKLLKPNGFLILSTMNRTPKSYLYTIV 181

Query: 163 GNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQR 222
              +YV   +P+             P ++ +++ +A  ++    G+  ++  L +   ++
Sbjct: 182 MA-EYVLNLVPRGTHEW---RKYVTPQEMVIFMNQANVKLYDVQGME-YNPLLNKAFIEK 236

Query: 223 DC 224
           + 
Sbjct: 237 NT 238


>UniRef50_B0SGJ1 Methylase/methyltransferase n=2 Tax=Leptospira biflexa serovar
           Patoc RepID=B0SGJ1_LEPBA
          Length = 199

 Score =  115 bits (289), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 55/208 (26%), Positives = 90/208 (43%), Gaps = 31/208 (14%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M+   FD IA ++        + QL + IL + L+ VL E+  + L  LD G G G   I
Sbjct: 1   MEPNVFDQIANQYDTE----ERIQLARHILAK-LEPVLLEISNKTL--LDFGCGTGLLGI 53

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
            +     +VIL D S  M+D      +AK + +       A  D+A     PVD IL   
Sbjct: 54  PLTSLYKEVILSDGSKVMLDVVDSKIKAKEIQNAKTI---APNDLAKSGALPVDHILMSL 110

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
           VL  + + + +L+T+ S L+PGG L L+ ++ +  + H  V   F  +            
Sbjct: 111 VLLHIPNTKQILETIHSYLKPGGTLYLIDFDENKKVSHPKVHSGFKQIA----------- 159

Query: 181 SPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
                     +   L+E G+Q +  + +
Sbjct: 160 ----------LMELLKEVGFQTVSSSII 177


>UniRef50_A8M6Z4 Methyltransferase type 11 n=5 Tax=Actinomycetales
           RepID=A8M6Z4_SALAI
          Length = 274

 Score =  115 bits (289), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 43/195 (22%), Positives = 80/195 (41%), Gaps = 23/195 (11%)

Query: 47  RVLDAGGGEGQTAIKMA-ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDV 105
           RVLD G G G+ AI++A     +V+   +S + ++RA++ A + G++D + F    A D+
Sbjct: 64  RVLDLGCGIGEPAIRLATAHTIEVVGISISGRQVERAQERAVSAGLADRLSFELADAMDL 123

Query: 106 ASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNF 165
             + E   D++     L  + D   VL+ +  VLRPGG +++  +      M    AG +
Sbjct: 124 P-YPEESFDIVWALESLHHMPDRAHVLRQMTRVLRPGGRVAIGDF------MLLPSAGGY 176

Query: 166 DYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCY 225
           +   A + +  K  LS             +  AG   +              +   +   
Sbjct: 177 EAGAARVNEASKGVLSVIGL---DAYLAMIRAAGLVPVAT------------EDVSKHTR 221

Query: 226 EALLELETRYCRQEP 240
            +  + E R+     
Sbjct: 222 PSWAKAEERFAALRE 236


>UniRef50_A8FSR8 Methylase involved in ubiquinone/menaquinone biosynthesis-like
           protein n=2 Tax=Shewanella RepID=A8FSR8_SHESH
          Length = 402

 Score =  115 bits (289), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 46/190 (24%), Positives = 86/190 (45%), Gaps = 14/190 (7%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEM--GPQKLRVLDAGGGEGQTAI 60
           D+    +   + +  Y +    +R     + L   +A+     + L+VLDAG G G   +
Sbjct: 2   DQTTSKVKNMYEQYPYPSGDPTIRAGFDIRLLLSYVAKKRGTDRPLQVLDAGCGRGPGVL 61

Query: 61  KMAERGHQV--ILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA--SHLETPVDLI 116
             A     V     D+++  +  A+  A+A+G++ N+ F+      +          D+I
Sbjct: 62  GAASLQPNVMFTAIDINSVGLAEARANAQARGLT-NINFVQADLMTLEGVEVPPGGFDVI 120

Query: 117 LFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGL-LMHNMVAG------NFDYVQ 169
               VL  +ADP+  L  L S+L P GV+SLM Y ++G   ++ ++ G      N D ++
Sbjct: 121 YSSGVLHHLADPQMGLNNLTSILAPHGVISLMLYGSYGRQALYRLIEGIDILSSNEDAIE 180

Query: 170 AGMPKKKKRT 179
           + +P  +  T
Sbjct: 181 SRLPLARALT 190


>UniRef50_D2B333 Methyltransferase type 11 n=4 Tax=Actinomycetales
           RepID=D2B333_STRRD
          Length = 281

 Score =  115 bits (289), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 44/170 (25%), Positives = 73/170 (42%), Gaps = 5/170 (2%)

Query: 37  VLAEMGPQKLRVLDAGGGEGQTAIKMAERG--HQVILCDLSAQMIDRAKQAAEAKGVSDN 94
           + A    ++ RVLD G G GQ     A R         DLSA M+ RA+  A  +GV+ N
Sbjct: 40  LAAAAVGERDRVLDVGCGNGQVTRLAARRARLGHTTGIDLSAPMLRRARACAADEGVA-N 98

Query: 95  MQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHG 154
           + F    AQ +    +   D+ +    + + ADP +    +   LRPGG L+ +     G
Sbjct: 99  VTFERGDAQ-IHPFPDAGFDVAVSRFGIMFFADPVAAFANIGRALRPGGRLAFLSLREMG 157

Query: 155 -LLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIM 203
              +  ++    D++ A           P+   DP ++   L  AG++ +
Sbjct: 158 DNDLGPVLTAMADHLPARPATTGPGAPGPESLADPGRIREVLTGAGFEAV 207


>UniRef50_Q8U2V0 Putative uncharacterized protein n=1 Tax=Pyrococcus furiosus
           RepID=Q8U2V0_PYRFU
          Length = 213

 Score =  115 bits (288), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 44/202 (21%), Positives = 81/202 (40%), Gaps = 14/202 (6%)

Query: 12  KFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVIL 71
           ++ R I   T G+L +A      DR+ + + P   RVLD G G G   ++ A RG +V  
Sbjct: 10  RYDRGIRIITLGKLDEA-----YDRLTSRIKP-GQRVLDVGCGTGALTLRAALRGARVKA 63

Query: 72  CDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRS- 130
            D++ QM++ A++  E  GV+  ++       ++ +      D ++       + +    
Sbjct: 64  IDINPQMLEIARKRVEEAGVTGMVELCEMGVAELNTEASEGYDAVMAGLCFSELTEDELS 123

Query: 131 -VLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPA 189
             L+ +  VL+PG +L +    A   +  + V     ++           L     R   
Sbjct: 124 YALREIKRVLKPGALLLI----ADEAVPESPVKRVLSWLIRAPLAVIAYLLIQTTTRAVK 179

Query: 190 QVYLWLEEAGWQIMGKTGVRVF 211
            +   L E G+ I      R F
Sbjct: 180 NLPEKLGEEGFLIESVR--RSF 199


>UniRef50_Q0W5X8 Ubiquinone/menaquinone biosynthesis methyltransferase n=1
           Tax=uncultured methanogenic archaeon RC-I
           RepID=Q0W5X8_UNCMA
          Length = 270

 Score =  115 bits (288), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 52/235 (22%), Positives = 100/235 (42%), Gaps = 27/235 (11%)

Query: 8   DIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMG-PQKLRVLDAGGGEGQTAIKMAERG 66
           ++AE + R    T+ GQL +  +      +++ MG     RVLD G G G+ A++++E  
Sbjct: 10  ELAEAYDR----TSDGQLEKGGV------LISRMGIGAGDRVLDVGCGTGRLALRVSELV 59

Query: 67  H---QVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
                V+  D S   I   ++   +   S +++F+   A+D++       D + + +V  
Sbjct: 60  GPSGCVVGVDPSEPRIALVRRKLASCEHS-SVRFVVGRAEDLSFLPGQAFDHVYYSSVFH 118

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKR--TLS 181
           W++D ++ L+  + VL PGG + +   +A  L     V    D +    P   +   +L+
Sbjct: 119 WISDKKAALREAFRVLAPGGRIGITTADAGDL---RNVPAVMDRLMLQPPYAGRVDASLA 175

Query: 182 PDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYC 236
              P    ++   L EAG+  +  T     H+       +     AL + E    
Sbjct: 176 ARRPVSRKELEAMLAEAGFGSIDVT----LHEL---NRVRSSPEAALEQAEADSA 223


>UniRef50_A7S2R8 Predicted protein n=1 Tax=Nematostella vectensis RepID=A7S2R8_NEMVE
          Length = 300

 Score =  115 bits (288), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 35/185 (18%), Positives = 74/185 (40%), Gaps = 6/185 (3%)

Query: 25  LRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQ 84
           +++A+L    + + +       ++LD G G G  A  +A  G +V   D SA+    A +
Sbjct: 95  IKKAVLGVQGEMLTSSKPLDGFKMLDVGCGGGLLAEPLARLGAKVTGIDASARNTHVAMR 154

Query: 85  AAE-AKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGG 143
            A     ++  +Q+     + +A   +   D ++   V+E V +  S +  +  +L+P G
Sbjct: 155 HASLDPSLAGKLQYRCITVEQLAQE-KKVFDCVVSSEVIEHVTEKESFIGAISQLLKPRG 213

Query: 144 VLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIM 203
            L L   N         +    +Y+   +P         +     +++   L+E G +  
Sbjct: 214 SLILTTMNRTPQAYVLAIVAA-EYIAHAVPIGTHDW---NKFPKISELTELLQENGLETE 269

Query: 204 GKTGV 208
              G+
Sbjct: 270 DIQGL 274


>UniRef50_B2JBN9 Methyltransferase type 11 n=2 Tax=Cyanobacteria RepID=B2JBN9_NOSP7
          Length = 278

 Score =  115 bits (288), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 44/201 (21%), Positives = 82/201 (40%), Gaps = 15/201 (7%)

Query: 8   DIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGH 67
            IA+ +SR       G     I  + ++   A + P   +VLD   G G  A++ A+   
Sbjct: 13  QIADLYSRRSSTYDNGDWHPRIAHRLVEY--AHIRP-GQQVLDIATGTGMVALEAAQIVG 69

Query: 68  ---QVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
              +VI  D+S  M+++A++   A G+S N++F    A+ +   L    D I   + L W
Sbjct: 70  AEGRVIGVDISTGMLEQARRKVAALGLS-NVEFQLADAEALDFPL-NSFDYIFCSSALIW 127

Query: 125 VADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDY 184
           ++D    L+  + +L+P G+L    +     +   +        Q  + K     L    
Sbjct: 128 MSDLVGALRLWYGLLKPKGLLGFHAFADTAFIEGVV-------AQRVLEKYGVSLLFSKP 180

Query: 185 PRDPAQVYLWLEEAGWQIMGK 205
                +    L+ AG+  +  
Sbjct: 181 TGTVEKCQKMLQLAGFSEIEI 201


>UniRef50_D0MGM2 Methyltransferase type 11 n=3 Tax=root RepID=D0MGM2_RHOM4
          Length = 274

 Score =  115 bits (288), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 49/185 (26%), Positives = 80/185 (43%), Gaps = 16/185 (8%)

Query: 25  LRQAILWQDLDRVLAEMG-PQKLRVLDAGGGEGQTAIKMAERG--HQVILCDLSAQMIDR 81
           LR   + + L R+       + +RVLDAG G GQ A  +A R    +V+  DL    +++
Sbjct: 33  LRSWYVRRALRRIFDRWPADRPVRVLDAGTGFGQYAYYIARRYPRAEVVGVDLKTDYLEQ 92

Query: 82  AKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRP 141
           A++      V+  ++F       +    E P DLIL   VLE + D R+VL+    VLRP
Sbjct: 93  ARRFVARTPVAGRVRFAQDDLTRL--QTEGPFDLILSVDVLEHIEDDRAVLRNFARVLRP 150

Query: 142 GGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQ 201
           GG + +   +  G        G   +++  + +   R L          +   L EAG +
Sbjct: 151 GGYVIINTPSDQG-GSDVQAPGQQSFIEEHVREGYSREL----------LEARLREAGLE 199

Query: 202 IMGKT 206
            +   
Sbjct: 200 PVESH 204


>UniRef50_B7KGA5 Methyltransferase type 11 n=2 Tax=Cyanothece RepID=B7KGA5_CYAP7
          Length = 260

 Score =  115 bits (288), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 53/279 (18%), Positives = 105/279 (37%), Gaps = 45/279 (16%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLR-VLDAGGGEGQTA 59
           M D N        S + +  T+ + + + +W+    ++  + PQ    +LD G G GQ  
Sbjct: 1   MNDPNL------TSTDQWDATRYETQHSFVWEYASDLIEILAPQAGEYILDLGCGTGQLT 54

Query: 60  IKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFH 119
            ++A +G   I  D S  MI  A +         N+QF+     D +   + P D +  +
Sbjct: 55  AQIAAQGAIAIGIDKSPTMIATASKN------YPNLQFLVADGADFSF--DYPFDGVFSN 106

Query: 120 AVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRT 179
           A L W+  P +V++ +   L+PGG     F     +     ++   + V        +  
Sbjct: 107 AALHWMTKPEAVIKCIGQALKPGGRFVAEFGGKGNI---KQISRAVETVLKTEGYPIESL 163

Query: 180 LSPDYPRDPAQVYLWLEEAGWQIM-------------GKTG----VRVFHDYLREKHQQR 222
           L+P Y     +    LE  G+ +               + G    +++F ++      + 
Sbjct: 164 LNPWYFPSIGEYATLLENEGFDVTFGVLFDRPTPLEAEQEGMKNWIKMFGNHWLSLIPES 223

Query: 223 DCYEALLELETRYCRQEPYI-----TLG--RYIHVTARK 254
           +      ++E       PY+      +   R + + A+K
Sbjct: 224 EQPAIFSKIEAAL---RPYLYGENHWIADYRRLRIVAQK 259


Searching..................................................done


Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_P36566 Protein smtA n=113 Tax=Gammaproteobacteria RepID...   322   8e-87
UniRef50_C4X686 S-adenosylmethionine-dependent methyltransferase...   293   5e-78
UniRef50_Q5QZ69 SAM-dependent methyltransferase n=3 Tax=Alteromo...   243   4e-63
UniRef50_A3QA14 Methyltransferase type 12 n=16 Tax=Gammaproteoba...   241   2e-62
UniRef50_B0TUI9 Methyltransferase type 12 n=65 Tax=Gammaproteoba...   237   2e-61
UniRef50_B3PES7 SmtA protein n=1 Tax=Cellvibrio japonicus Ueda10...   235   9e-61
UniRef50_Q2SJW8 SAM-dependent methyltransferase n=1 Tax=Hahella ...   229   6e-59
UniRef50_Q1YTE5 Possible methyltransferase n=1 Tax=gamma proteob...   227   3e-58
UniRef50_Q1ZIA5 SmtA protein n=2 Tax=Gammaproteobacteria RepID=Q...   227   4e-58
UniRef50_A4XQ92 Methyltransferase type 11 n=17 Tax=Pseudomonas R...   221   2e-56
UniRef50_Q31JJ3 SAM-dependent methyltransferase n=3 Tax=Pisciric...   215   1e-54
UniRef50_A4VI82 Methyltransferase, putative n=5 Tax=Pseudomonada...   213   4e-54
UniRef50_C5BHU7 SAM-dependent methyltransferase n=1 Tax=Teredini...   213   4e-54
UniRef50_UPI0000E11711 methyltransferase type 11 n=1 Tax=Glaciec...   212   7e-54
UniRef50_Q15TU3 Methyltransferase type 11 n=1 Tax=Pseudoalteromo...   212   9e-54
UniRef50_Q21JL0 Methyltransferase type 12 n=1 Tax=Saccharophagus...   211   2e-53
UniRef50_B4RYI5 SAM-dependent methyltransferase n=2 Tax=Alteromo...   207   2e-52
UniRef50_Q1QA01 Methyltransferase type 11 n=4 Tax=Moraxellaceae ...   204   2e-51
UniRef50_A5EV89 S-adenosylmethionine-dependent methyltransferase...   202   1e-50
UniRef50_Q1QUF1 SmtA protein n=1 Tax=Chromohalobacter salexigens...   198   1e-49
UniRef50_Q1N5H2 SAM-dependent methyltransferase n=1 Tax=Bermanel...   195   1e-48
UniRef50_Q2NUA0 Putative S-adenosylmethionine-dependent methyltr...   187   3e-46
UniRef50_B5L6J9 Methyltransferase n=1 Tax=Micromonospora chalcea...   181   3e-44
UniRef50_C8SD34 Methyltransferase type 11 n=1 Tax=Ferroglobus pl...   181   3e-44
UniRef50_B9K8U5 Ubiquinone/menaquinone biosynthesis methyltransf...   179   8e-44
UniRef50_B0U3W1 3-demethylubiquinone-9 3-methyltransferase n=7 T...   178   1e-43
UniRef50_C9R8S5 Methyltransferase type 11 n=1 Tax=Ammonifex dege...   176   6e-43
UniRef50_Q1QEI9 3-demethylubiquinone-9 3-methyltransferase n=59 ...   176   7e-43
UniRef50_Q46F96 Ubiquinone/menaquinone biosynthesis methyltransf...   175   2e-42
UniRef50_D1JEE5 Putative uncharacterized protein n=1 Tax=uncultu...   174   3e-42
UniRef50_B3TMR6 SAM-dependent methyltransferase n=1 Tax=Actinoma...   174   3e-42
UniRef50_B8HNX7 Ubiquinone biosynthesis O-methyltransferase n=1 ...   174   3e-42
UniRef50_Q9NZJ6 Hexaprenyldihydroxybenzoate methyltransferase, m...   173   6e-42
UniRef50_B3S9Y1 Putative uncharacterized protein n=1 Tax=Trichop...   173   7e-42
UniRef50_Q21UL3 3-demethylubiquinone-9 3-methyltransferase n=5 T...   172   9e-42
UniRef50_D1JD55 Putative uncharacterized protein n=1 Tax=uncultu...   172   1e-41
UniRef50_C0Q9K2 UbiG n=1 Tax=Desulfobacterium autotrophicum HRM2...   171   2e-41
UniRef50_A0L9I8 3-demethylubiquinone-9 3-methyltransferase n=2 T...   171   2e-41
UniRef50_Q28VP7 3-demethylubiquinone-9 3-methyltransferase n=37 ...   171   3e-41
UniRef50_D1JD67 Putative uncharacterized protein n=1 Tax=uncultu...   171   3e-41
UniRef50_B8GRY2 Ubiquinone biosynthesis O-methyltransferase n=1 ...   170   5e-41
UniRef50_Q2FMN6 UbiE/COQ5 methyltransferase n=1 Tax=Methanospiri...   170   5e-41
UniRef50_Q0F561 3-demethylubiquinone-9 3-methyltransferase n=2 T...   169   7e-41
UniRef50_D1V817 Methyltransferase type 12 n=2 Tax=Frankia RepID=...   169   8e-41
UniRef50_A7MPA9 3-demethylubiquinone-9 3-methyltransferase n=6 T...   169   1e-40
UniRef50_D2SA73 Methyltransferase type 11 n=1 Tax=Geodermatophil...   169   1e-40
UniRef50_A0Y980 3-demethylubiquinone-9 3-methyltransferase n=1 T...   169   1e-40
UniRef50_B7MFZ8 3-demethylubiquinone-9 3-methyltransferase n=131...   168   2e-40
UniRef50_D2LFP9 Ubiquinone biosynthesis O-methyltransferase n=1 ...   168   3e-40
UniRef50_Q6MHC4 3-demethylubiquinone-9 3-methyltransferase n=1 T...   167   3e-40
UniRef50_Q2FPU4 UbiE/COQ5 methyltransferase n=1 Tax=Methanospiri...   167   3e-40
UniRef50_C5CH90 Methyltransferase type 11 n=1 Tax=Kosmotoga olea...   167   3e-40
UniRef50_C4XNC1 Putative 3-demethylubiquinone-9 3-methyltransfer...   167   3e-40
UniRef50_Q482G8 3-demethylubiquinone-9 3-methyltransferase n=27 ...   167   4e-40
UniRef50_Q2NSL7 3-demethylubiquinone-9 3-methyltransferase n=305...   166   1e-39
UniRef50_Q8TJ84 UbiE/COQ5 methyltransferase n=1 Tax=Methanosarci...   165   1e-39
UniRef50_B6YVU2 UbiE/COQ5 methyltransferase n=4 Tax=Thermococcus...   165   1e-39
UniRef50_A3TKD6 Putative methyltransferase n=1 Tax=Janibacter sp...   165   1e-39
UniRef50_B8H209 3-demethylubiquinone-9 3-methyltransferase n=13 ...   164   4e-39
UniRef50_B6BTP2 3-demethylubiquinone-9 3-O-methyltransferase n=1...   163   4e-39
UniRef50_O74421 Hexaprenyldihydroxybenzoate methyltransferase, m...   163   4e-39
UniRef50_Q6DHK4 Coenzyme Q3 homolog, methyltransferase (Yeast) n...   163   5e-39
UniRef50_Q5WW02 3-demethylubiquinone-9 3-methyltransferase n=4 T...   163   6e-39
UniRef50_D0NUY8 3-demethylubiquinone-9 3-methyltransferase, puta...   162   8e-39
UniRef50_C1MP91 Predicted protein n=1 Tax=Micromonas pusilla CCM...   162   1e-38
UniRef50_B9M2E9 Ubiquinone biosynthesis O-methyltransferase n=1 ...   162   1e-38
UniRef50_UPI000186D07C hexaprenyldihydroxybenzoate methyltransfe...   162   1e-38
UniRef50_A4BJS3 Putative SmtA protein n=1 Tax=Reinekea blandensi...   161   1e-38
UniRef50_D1JD52 Putative uncharacterized protein n=1 Tax=uncultu...   161   1e-38
UniRef50_B7FTF3 Predicted protein (Fragment) n=1 Tax=Phaeodactyl...   161   1e-38
UniRef50_C7QBJ1 Methyltransferase type 12 n=15 Tax=Actinomycetal...   161   2e-38
UniRef50_Q3SVP3 3-demethylubiquinone-9 3-methyltransferase n=45 ...   161   2e-38
UniRef50_C8WEG5 Ubiquinone biosynthesis O-methyltransferase n=3 ...   161   3e-38
UniRef50_C3YXC3 Putative uncharacterized protein n=1 Tax=Branchi...   161   3e-38
UniRef50_A8PNX2 3-demethylubiquinone-9 3-O-methyltransferase n=1...   161   3e-38
UniRef50_A3TLQ5 S-adenosylmethionine-dependent methyltransferase...   161   3e-38
UniRef50_UPI0000E495F1 PREDICTED: hypothetical protein n=2 Tax=S...   161   3e-38
UniRef50_A5EVK0 Ubiquinone biosynthesis O-methyltransferase n=2 ...   161   3e-38
UniRef50_Q5VMJ1 Putative dihydroxypolyprenylbenzoate methyltrans...   160   3e-38
UniRef50_Q48938 Orf3 protein n=3 Tax=Methanosarcina RepID=Q48938...   160   4e-38
UniRef50_A4FIW0 Methyltransferase n=3 Tax=Actinomycetales RepID=...   160   4e-38
UniRef50_D1JD78 Putative uncharacterized protein n=1 Tax=uncultu...   160   4e-38
UniRef50_O49354 Hexaprenyldihydroxybenzoate methyltransferase, m...   160   5e-38
UniRef50_A2SPT6 Methyltransferase type 11 n=2 Tax=Methanomicrobi...   160   5e-38
UniRef50_C6PRH7 Methyltransferase type 11 n=1 Tax=Clostridium ca...   160   6e-38
UniRef50_D2RYJ5 Methyltransferase type 11 n=3 Tax=Haloterrigena ...   160   6e-38
UniRef50_Q65VD6 SmtA protein n=2 Tax=Gammaproteobacteria RepID=Q...   159   7e-38
UniRef50_Q8RJX7 Methyl transferase n=1 Tax=Stigmatella aurantiac...   159   8e-38
UniRef50_B6K7D4 Hexaprenyldihydroxybenzoate methyltransferase n=...   159   9e-38
UniRef50_Q5PAV2 3-demethylubiquinone-9 3-methyltransferase n=1 T...   159   1e-37
UniRef50_Q8TIA7 Phosphatidylethanolamine N-methyltransferase n=3...   159   1e-37
UniRef50_B1KQ47 Ubiquinone biosynthesis O-methyltransferase n=3 ...   158   1e-37
UniRef50_B9JTF4 Ubiquinone biosynthesis O-methyltransferase n=1 ...   158   1e-37
UniRef50_A0ZM88 3-demethylubiquinone-9 3-methyltransferase n=1 T...   158   1e-37
UniRef50_A0LNU5 3-demethylubiquinone-9 3-methyltransferase n=1 T...   158   1e-37
UniRef50_A4B9Z3 3-demethylubiquinone-9 3-methyltransferase n=2 T...   158   2e-37
UniRef50_C0ZNJ7 Putative methyltransferase n=1 Tax=Rhodococcus e...   158   2e-37
UniRef50_C5KJI6 3-demethylubiquinone-9 3-methyltransferase, puta...   158   2e-37
UniRef50_D1RIV9 3-demethylubiquinone-9 3-O-methyltransferase n=1...   158   2e-37
UniRef50_UPI000051ABE2 PREDICTED: similar to coenzyme Q3 homolog...   157   3e-37
UniRef50_A7S2R8 Predicted protein n=1 Tax=Nematostella vectensis...   157   3e-37
UniRef50_Q7Q8W1 AGAP010535-PA n=1 Tax=Anopheles gambiae RepID=Q7...   157   3e-37
UniRef50_B4RRL2 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-ben...   157   3e-37
UniRef50_A8MFN6 Methyltransferase type 11 n=1 Tax=Alkaliphilus o...   157   4e-37
UniRef50_Q5WCE8 S-adenosylmethionine (SAM)-dependent methyltrans...   156   5e-37
UniRef50_Q2FPT3 UbiE/COQ5 methyltransferase n=1 Tax=Methanospiri...   156   6e-37
UniRef50_A1HPJ4 Methyltransferase type 11 n=1 Tax=Thermosinus ca...   156   7e-37
UniRef50_Q465A3 UbiE/COQ5 methyltransferase n=3 Tax=Methanomicro...   156   7e-37
UniRef50_Q88SI6 Menaquinone biosynthesis methyltransferase ubiE ...   156   7e-37
UniRef50_A8M0L9 Methyltransferase type 12 n=1 Tax=Salinispora ar...   156   7e-37
UniRef50_Q235E0 Ubiquinone biosynthesis O-methyltransferase fami...   156   8e-37
UniRef50_B8EI29 3-demethylubiquinone-9 3-methyltransferase n=1 T...   156   8e-37
UniRef50_B2S828 3-demethylubiquinone-9 3-methyltransferase n=46 ...   156   8e-37
UniRef50_Q467Y8 Methyltransferase n=2 Tax=Methanosarcina RepID=Q...   155   1e-36
UniRef50_Q1JXN0 Methyltransferase type 11 n=1 Tax=Desulfuromonas...   155   1e-36
UniRef50_Q2GKA5 3-demethylubiquinone-9 3-methyltransferase n=7 T...   155   1e-36
UniRef50_Q0S6F7 3-demethylubiquinone-9 3-O-methyltransferase n=3...   155   2e-36
UniRef50_C6P0T7 Methyltransferase type 11 n=1 Tax=Sideroxydans l...   155   2e-36
UniRef50_B2J5L2 Methyltransferase type 11 n=1 Tax=Nostoc punctif...   154   2e-36
UniRef50_B4V3L4 Methyltransferase n=17 Tax=Streptomyces RepID=B4...   154   2e-36
UniRef50_C9L9K2 SmtA protein n=6 Tax=Bacteria RepID=C9L9K2_RUMHA      154   3e-36
UniRef50_C8Q6G5 Methyltransferase type 11 n=1 Tax=Pantoea sp. At...   154   3e-36
UniRef50_C9NJ50 Methyltransferase type 12 n=8 Tax=Streptomyces R...   154   4e-36
UniRef50_Q46D00 UbiE/COQ5 methyltransferase n=2 Tax=Methanosarci...   154   4e-36
UniRef50_Q8TNX2 Putative uncharacterized protein n=1 Tax=Methano...   153   4e-36
UniRef50_Q1GR70 3-demethylubiquinone-9 3-methyltransferase n=1 T...   153   6e-36
UniRef50_Q67LE6 Menaquinone biosynthesis methyltransferase ubiE ...   153   6e-36
UniRef50_Q46ER7 UbiE/COQ5 methyltransferase n=4 Tax=Methanosarci...   153   6e-36
UniRef50_Q012C7 Dihydroxypolyprenylbenzoate methyltransferase (I...   153   8e-36
UniRef50_Q3MEY9 Cyclopropane-fatty-acyl-phospholipid synthase n=...   153   8e-36
UniRef50_D1YW16 ABC transporter ATP binding protein n=3 Tax=Meth...   153   8e-36
UniRef50_A8TN90 Ubiquinone biosynthesis O-methyltransferase n=1 ...   153   8e-36
UniRef50_B0XJ66 3-demethylubiquinone-9 3-methyltransferase n=2 T...   152   9e-36
UniRef50_A4S2A7 Predicted protein n=1 Tax=Ostreococcus lucimarin...   152   9e-36
UniRef50_Q465A0 Putative uncharacterized protein n=2 Tax=Methano...   152   1e-35
UniRef50_A8MFN7 Methyltransferase type 11 n=1 Tax=Alkaliphilus o...   152   1e-35
UniRef50_A6UUC3 Methyltransferase type 11 n=1 Tax=Methanococcus ...   152   1e-35
UniRef50_B1I4Q7 Methyltransferase type 11 n=1 Tax=Candidatus Des...   151   2e-35
UniRef50_A9ILA7 Ubiquinone/menaquinone biosynthesis methyltransf...   151   2e-35
UniRef50_Q7VRW8 3-demethylubiquinone-9 3-methyltransferase n=2 T...   151   2e-35
UniRef50_C7PC96 Methyltransferase type 11 n=1 Tax=Chitinophaga p...   151   2e-35
UniRef50_Q2W6W0 3-demethylubiquinone-9 3-methyltransferase n=7 T...   151   2e-35
UniRef50_B1BEI5 Probable S-adenosylmethionine-dependent methltra...   151   2e-35
UniRef50_D1BE92 Methylase involved in ubiquinone/menaquinone bio...   150   4e-35
UniRef50_A9MCZ2 Ubiquinone/menaquinone biosynthesis methyltransf...   150   4e-35
UniRef50_A9KR97 Methyltransferase type 11 n=1 Tax=Clostridium ph...   150   4e-35
UniRef50_A7I8W9 Methyltransferase type 11 n=3 Tax=Methanomicrobi...   150   5e-35
UniRef50_B0C971 Methyltransferase, putative n=1 Tax=Acaryochlori...   149   5e-35
UniRef50_C1E266 Predicted protein (Fragment) n=6 Tax=cellular or...   149   7e-35
UniRef50_Q8TJW5 Putative uncharacterized protein n=1 Tax=Methano...   149   9e-35
UniRef50_B9XIN5 Ubiquinone/menaquinone biosynthesis methyltransf...   148   1e-34
UniRef50_Q5GT88 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-be...   148   1e-34
UniRef50_C7MMN1 Methylase involved in ubiquinone/menaquinone bio...   148   1e-34
UniRef50_D1JD56 Putative uncharacterized protein n=1 Tax=uncultu...   148   2e-34
UniRef50_D0LMD2 Methyltransferase type 11 n=1 Tax=Haliangium och...   148   2e-34
UniRef50_A6WCY9 Methyltransferase type 12 n=2 Tax=Actinomycetale...   148   2e-34
UniRef50_B0MSN4 Putative uncharacterized protein n=1 Tax=Alistip...   148   2e-34
UniRef50_A6TPQ5 Methyltransferase type 11 n=1 Tax=Alkaliphilus m...   148   2e-34
UniRef50_UPI0001B4EB31 methyltransferase n=1 Tax=Streptomyces sp...   148   2e-34
UniRef50_A8J700 C5-O-methyltransferase n=4 Tax=Streptomyces RepI...   148   2e-34
UniRef50_Q2JD64 Methyltransferase type 11 n=2 Tax=Frankia RepID=...   148   3e-34
UniRef50_Q2RJ99 UbiE/COQ5 methyltransferase n=1 Tax=Moorella the...   148   3e-34
UniRef50_A5ZYR5 Putative uncharacterized protein (Fragment) n=1 ...   147   3e-34
UniRef50_Q8NMH1 SAM-dependent methyltransferases n=2 Tax=Coryneb...   147   3e-34
UniRef50_Q17BU7 Hexaprenyldihydroxybenzoate methyltransferase n=...   147   3e-34
UniRef50_D0RTX5 S-adenosylmethionine-dependent methyltransferase...   147   4e-34
UniRef50_Q8TPQ8 UbiE/COQ5 methyltransferase n=1 Tax=Methanosarci...   147   4e-34
UniRef50_Q9ALM7 Methyltransferase-like protein n=2 Tax=Saccharop...   147   4e-34
UniRef50_D2UX54 Predicted protein (Fragment) n=1 Tax=Naegleria g...   147   4e-34
UniRef50_Q46F92 Putative uncharacterized protein n=2 Tax=Methano...   147   4e-34
UniRef50_B0A8V1 Putative uncharacterized protein n=1 Tax=Clostri...   146   6e-34
UniRef50_C9L9K1 SmtA protein n=1 Tax=Blautia hansenii DSM 20583 ...   146   6e-34
UniRef50_Q3A5P1 Putative methyltransferase n=1 Tax=Pelobacter ca...   146   1e-33
UniRef50_UPI0001AF209D methyltransferase type 11 n=1 Tax=Strepto...   146   1e-33
UniRef50_C8W4V3 Methyltransferase type 11 n=1 Tax=Desulfotomacul...   145   1e-33
UniRef50_A4FLY1 Methyltransferase n=1 Tax=Saccharopolyspora eryt...   145   1e-33
UniRef50_A1R990 Menaquinone biosynthesis methyltransferase ubiE ...   145   1e-33
UniRef50_C6C7H1 Methyltransferase type 11 n=3 Tax=Enterobacteria...   145   1e-33
UniRef50_D1C573 Methyltransferase type 11 n=1 Tax=Sphaerobacter ...   145   2e-33
UniRef50_C6CNR0 Methyltransferase type 11 n=2 Tax=Dickeya RepID=...   145   2e-33
UniRef50_D1VJQ5 Methyltransferase type 12 n=1 Tax=Frankia sp. Eu...   144   2e-33
UniRef50_C7Q6F0 Methyltransferase type 11 n=1 Tax=Catenulispora ...   144   2e-33
UniRef50_A1TE65 Methyltransferase type 11 n=1 Tax=Mycobacterium ...   144   2e-33
UniRef50_B6IUU0 3-demethylubiquinone-9 3-methyltransferase n=4 T...   144   2e-33
UniRef50_Q1D7Y1 Methyltransferase, UbiE/COQ5 family n=2 Tax=Myxo...   144   2e-33
UniRef50_A4X7A0 Methyltransferase type 11 n=9 Tax=Bacteria RepID...   144   2e-33
UniRef50_B5JEA6 Methyltransferase domain family n=1 Tax=Verrucom...   144   2e-33
UniRef50_Q01W19 Demethylmenaquinone methyltransferase n=1 Tax=Ca...   144   3e-33
UniRef50_A4Z3A6 Putative uncharacterized protein n=1 Tax=Bradyrh...   144   3e-33
UniRef50_Q5UF03 Predicted 2-polyprenyl-3-methyl-5-hydroxy-6-meto...   144   3e-33
UniRef50_B1I444 Methyltransferase type 11 n=1 Tax=Candidatus Des...   144   4e-33
UniRef50_B0C5W7 3-demethylubiquinone-9 3-methyltransferase n=2 T...   143   4e-33
UniRef50_P67065 Menaquinone biosynthesis methyltransferase ubiE ...   143   6e-33
UniRef50_A2R6K2 Catalytic activity: S-adenosyl-L-methionine + 5a...   143   6e-33
UniRef50_Q846Y0 Monensin 3-O-methyl transferase n=1 Tax=Streptom...   143   8e-33
UniRef50_A7AUT3 Ubiquinone biosynthesis O-methyltransferase fami...   142   1e-32
UniRef50_A7HZC3 Ubiquinone/menaquinone biosynthesis methyltransf...   142   1e-32
UniRef50_B0A8V0 Putative uncharacterized protein n=1 Tax=Clostri...   142   1e-32
UniRef50_Q9K8W5 BH2887 protein n=1 Tax=Bacillus halodurans RepID...   142   1e-32
UniRef50_C4G5R9 Putative uncharacterized protein n=1 Tax=Abiotro...   142   1e-32
UniRef50_B2JBN9 Methyltransferase type 11 n=2 Tax=Cyanobacteria ...   142   1e-32
UniRef50_A8ICE1 Hexaprenyldihydroxybenzoate methyltransferase (F...   142   1e-32
UniRef50_B8GH63 Methyltransferase type 11 n=1 Tax=Methanosphaeru...   142   1e-32
UniRef50_D0LH47 Ubiquinone/menaquinone biosynthesis methyltransf...   142   1e-32
UniRef50_B0C3T5 Methyltransferase n=8 Tax=Bacteria RepID=B0C3T5_...   142   1e-32
UniRef50_C9N657 Methyltransferase type 11 n=2 Tax=Streptomyces R...   142   1e-32
UniRef50_UPI0001A4295A methyltransferase type 11 n=1 Tax=Pectoba...   142   1e-32
UniRef50_Q67LB5 Conserved domain protein n=1 Tax=Symbiobacterium...   142   1e-32
UniRef50_B5GJM0 Methyltransferase n=2 Tax=Streptomyces RepID=B5G...   141   2e-32
UniRef50_B8G0Y2 Methyltransferase type 11 n=1 Tax=Desulfitobacte...   141   2e-32
UniRef50_D0BKF2 SmtA protein n=1 Tax=Granulicatella elegans ATCC...   141   2e-32
UniRef50_O18235 Protein Y57G11C.11a, confirmed by transcript evi...   141   2e-32
UniRef50_C9LTF9 SmtA protein n=2 Tax=Veillonellaceae RepID=C9LTF...   141   3e-32
UniRef50_A1WUJ9 3-demethylubiquinone-9 3-methyltransferase n=1 T...   141   3e-32
UniRef50_Q72HI4 Menaquinone biosynthesis methyltransferase ubiE ...   141   3e-32
UniRef50_A6UGV5 Methyltransferase type 11 n=3 Tax=Rhizobiaceae R...   140   4e-32
UniRef50_A5UZ15 Methyltransferase type 11 n=2 Tax=Roseiflexus Re...   140   4e-32
UniRef50_C1B334 Putative uncharacterized protein n=2 Tax=Bacteri...   140   5e-32
UniRef50_Q11GJ5 Methyltransferase type 11 n=2 Tax=Alphaproteobac...   140   5e-32
UniRef50_A9CF50 Methyltransferase n=16 Tax=Alphaproteobacteria R...   140   5e-32
UniRef50_B8FPB3 Methyltransferase type 11 n=4 Tax=Clostridiales ...   140   5e-32
UniRef50_Q9RYC4 Methyltransferase, putative n=2 Tax=Deinococcus ...   140   5e-32
UniRef50_C6PBK3 Methyltransferase type 11 n=1 Tax=Thermoanaeroba...   140   5e-32
UniRef50_A4FIY5 Ubiquinone/menaquinone biosynthesis methyltransf...   140   5e-32
UniRef50_C8XH01 Methyltransferase type 11 n=1 Tax=Nakamurella mu...   140   5e-32
UniRef50_D1YX02 Methyltransferase n=1 Tax=Methanocella paludicol...   140   5e-32
UniRef50_B3E0R3 Methylase involved in ubiquinone/menaquinone bio...   139   6e-32
UniRef50_A7Z1X4 Putative uncharacterized protein n=1 Tax=Bacillu...   139   6e-32
UniRef50_Q73R34 Methlytransferase, UbiE/COQ5 family n=1 Tax=Trep...   139   6e-32
UniRef50_A9GFV3 Trans-aconitate 2-methyltransferase n=1 Tax=Sora...   139   6e-32
UniRef50_A9GFL2 Ubiquinone/menaquinone biosynthesis methyltransf...   139   7e-32
UniRef50_B8H5N0 Methyltransferase n=3 Tax=Caulobacter RepID=B8H5...   139   7e-32
UniRef50_A8LNN9 3-demethylubiquinone-9 3-methyltransferase n=8 T...   139   8e-32
UniRef50_UPI0001758A2F PREDICTED: similar to hexaprenyldihydroxy...   139   8e-32
UniRef50_UPI0001B5455F methyltransferase type 11 n=1 Tax=Strepto...   139   9e-32
UniRef50_Q9EYI2 SnogM n=1 Tax=Streptomyces nogalater RepID=Q9EYI...   139   9e-32
UniRef50_C5A2C6 SAM-dependent methyltransferase, ubiE/COQ5 famil...   139   1e-31
UniRef50_B8G1N6 Methyltransferase type 11 n=1 Tax=Desulfitobacte...   139   1e-31
UniRef50_C8VZ57 Methyltransferase type 11 n=1 Tax=Desulfotomacul...   139   1e-31
UniRef50_Q89BX8 Bll8020 protein n=1 Tax=Bradyrhizobium japonicum...   139   1e-31
UniRef50_A6ULP8 Methyltransferase type 11 n=2 Tax=Proteobacteria...   139   1e-31

Sequences not found previously or not previously below threshold:

UniRef50_A1UUE1 Ubiquinone/menaquinone biosynthesis methyltransf...   144   2e-33
UniRef50_B7QF56 Dihydroxypolyprenylbenzoate methyltransferase, p...   144   3e-33
UniRef50_UPI00006A654D PREDICTED: similar to Hexaprenyldihydroxy...   143   4e-33
UniRef50_Q75FL1 Menaquinone biosynthesis methyltransferase ubiE ...   142   1e-32
UniRef50_B0CTS7 Predicted protein n=2 Tax=Agaricales RepID=B0CTS...   141   2e-32
UniRef50_UPI0001924F25 PREDICTED: similar to coenzyme Q3 homolog...   140   3e-32
UniRef50_C4Q545 Hexaprenyldihydroxybenzoate methyltransferase, p...   139   8e-32
UniRef50_Q74LY0 Menaquinone biosynthesis methyltransferase ubiE ...   139   9e-32
UniRef50_Q2FUA7 UbiE/COQ5 methyltransferase n=1 Tax=Methanospiri...   139   1e-31

>UniRef50_P36566 Protein smtA n=113 Tax=Gammaproteobacteria RepID=SMTA_ECOLI
          Length = 261

 Score =  322 bits (826), Expect = 8e-87,   Method: Composition-based stats.
 Identities = 261/261 (100%), Positives = 261/261 (100%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI
Sbjct: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
           KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA
Sbjct: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
           VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL
Sbjct: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180

Query: 181 SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP 240
           SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP
Sbjct: 181 SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP 240

Query: 241 YITLGRYIHVTARKPQSKDKV 261
           YITLGRYIHVTARKPQSKDKV
Sbjct: 241 YITLGRYIHVTARKPQSKDKV 261


>UniRef50_C4X686 S-adenosylmethionine-dependent methyltransferase n=56
           Tax=Enterobacteriaceae RepID=C4X686_KLEPN
          Length = 270

 Score =  293 bits (750), Expect = 5e-78,   Method: Composition-based stats.
 Identities = 207/265 (78%), Positives = 229/265 (86%), Gaps = 5/265 (1%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIK 61
           QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDL+ +LA++GP  LRVLDAGGGEGQTAIK
Sbjct: 6   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLEPLLAQLGPGPLRVLDAGGGEGQTAIK 65

Query: 62  MAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
           +A+ GH V LCDLSA+M+ RA+QAA  KGV DNM F+ CAAQD+A HLE+PVDL+LFHAV
Sbjct: 66  VAQLGHHVTLCDLSAEMVARARQAAADKGVIDNMHFVQCAAQDIAQHLESPVDLVLFHAV 125

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLS 181
           LEWVA+P+ +L TLWS LR GG LSLMFYNA+GLLMHNMVAGNFDYVQ GMPKKKKRTLS
Sbjct: 126 LEWVAEPQEILHTLWSTLRAGGGLSLMFYNANGLLMHNMVAGNFDYVQLGMPKKKKRTLS 185

Query: 182 PDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPY 241
           PDYPR+P QVY WLEE GWQI+ KTGVRVFHDYLREK QQ D Y ALL LETRYCRQEPY
Sbjct: 186 PDYPREPQQVYHWLEEIGWQIVSKTGVRVFHDYLREKRQQHDSYAALLALETRYCRQEPY 245

Query: 242 ITLGRYIHVTARKP-----QSKDKV 261
           ++LGRYIHVTA K      + KDKV
Sbjct: 246 LSLGRYIHVTALKSQAHSRRCKDKV 270


>UniRef50_Q5QZ69 SAM-dependent methyltransferase n=3 Tax=Alteromonadales
           RepID=Q5QZ69_IDILO
          Length = 262

 Score =  243 bits (621), Expect = 4e-63,   Method: Composition-based stats.
 Identities = 108/256 (42%), Positives = 152/256 (59%), Gaps = 5/256 (1%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           F  I++KFS++IY TTKGQLR  +L +DL  +LA    +   VLD G G GQ      E+
Sbjct: 11  FSGISQKFSKSIYDTTKGQLRVEVLKRDLAPLLAT---EPCLVLDVGAGLGQVNQWFQEK 67

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA-SHLETPVDLILFHAVLEW 124
           G  V+  DLS +MI+ A++  +A G+    +++  +  ++      +  D+IL HAVLEW
Sbjct: 68  GFTVVHSDLSTEMIEEAERRHKAAGLGHKCKYVAASLTELVNQQPLSQYDIILCHAVLEW 127

Query: 125 VADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDY 184
           + D    +  L S+L+PGG LSLMFYN H  L  N + GNFDY++ G+  KK   LSP+ 
Sbjct: 128 LPDTELAIHQLASLLKPGGKLSLMFYNYHAKLFANAIYGNFDYIERGLKVKKTVRLSPEN 187

Query: 185 PRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPYITL 244
           P  P QV  WLE+ G  +  KTGVR FHDYLR+   Q+  ++ LL LE +Y +  PY  L
Sbjct: 188 PAVPEQVGCWLEQEGLNVQQKTGVRCFHDYLRDLTHQQR-FDELLALEMKYNQMSPYREL 246

Query: 245 GRYIHVTARKPQSKDK 260
           GRY H    KP  +++
Sbjct: 247 GRYQHWLIEKPNCQEE 262


>UniRef50_A3QA14 Methyltransferase type 12 n=16 Tax=Gammaproteobacteria
           RepID=A3QA14_SHELP
          Length = 284

 Score =  241 bits (616), Expect = 2e-62,   Method: Composition-based stats.
 Identities = 101/256 (39%), Positives = 150/256 (58%), Gaps = 4/256 (1%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIK 61
           QD+NFD +A KF++NIYGT KG++R A+LW+D+ + + ++    LR+LDAGGG G  + K
Sbjct: 26  QDKNFDALAGKFAKNIYGTPKGEVRAAVLWRDISQAMTQLPEGPLRILDAGGGFGFFSQK 85

Query: 62  MAERGHQVILCDLSAQMIDRAKQAAEA----KGVSDNMQFIHCAAQDVASHLETPVDLIL 117
           +A+ GH V LCD+S++M+   +          G   ++  +H   Q +        DLIL
Sbjct: 86  LAKLGHSVTLCDISSEMLALGQAQITEYENNSGEKLDITLLHAPIQSLTREELGQFDLIL 145

Query: 118 FHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKK 177
            HAV EW++D +  L  L  +L+P G+ SLMFYN   +  H++++GNFDYV A    KKK
Sbjct: 146 CHAVAEWLSDAKQTLAGLTQLLKPQGLFSLMFYNKEAMRFHSLISGNFDYVAADFKVKKK 205

Query: 178 RTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCR 237
             L+P YP     V  W+ +   +++  +GVRV HDYL+        +  LLE+E +Y  
Sbjct: 206 VGLTPSYPLYIDDVRGWVSDWQMELVTASGVRVIHDYLKTHQPPNSDFSQLLEMELQYST 265

Query: 238 QEPYITLGRYIHVTAR 253
              YI LGRY+H   R
Sbjct: 266 HPAYIGLGRYVHFITR 281


>UniRef50_B0TUI9 Methyltransferase type 12 n=65 Tax=Gammaproteobacteria
           RepID=B0TUI9_SHEHH
          Length = 287

 Score =  237 bits (606), Expect = 2e-61,   Method: Composition-based stats.
 Identities = 124/261 (47%), Positives = 176/261 (67%), Gaps = 6/261 (2%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQK------LRVLDAGGGE 55
           QDRNFD +A KF+ +IYGT KG++RQ ++WQD++++L  +  Q       L VLDAGGG 
Sbjct: 27  QDRNFDGLAHKFAASIYGTAKGEIRQTVVWQDIEQILLALSKQPSNAAAELSVLDAGGGL 86

Query: 56  GQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDL 115
            Q + K+A  GH V LCDLS++M+  AKQ      +    QFIH   Q++A HL+ PVDL
Sbjct: 87  AQLSQKIAALGHNVSLCDLSSEMLSLAKQDISDNQLLKKYQFIHSPVQNIAEHLQVPVDL 146

Query: 116 ILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKK 175
           ILFHAV+EW+A+P   L TL   ++PGG++S+MFYN +GLL  N++ GN ++++ GMP +
Sbjct: 147 ILFHAVMEWLAEPIQALSTLCEQVKPGGIISVMFYNYNGLLFKNLICGNLNHIEKGMPHR 206

Query: 176 KKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRY 235
           K+  L P     P  VY  LE+AG+ I+GKTGVR FHDY++        +E ++ +E + 
Sbjct: 207 KRFKLQPQQGIKPELVYSCLEQAGFNILGKTGVRTFHDYMQNHDMGDFSFEQIVAMEQKL 266

Query: 236 CRQEPYITLGRYIHVTARKPQ 256
           CRQEP+++LGRYIHV A+K  
Sbjct: 267 CRQEPFLSLGRYIHVYAQKSA 287


>UniRef50_B3PES7 SmtA protein n=1 Tax=Cellvibrio japonicus Ueda107
           RepID=B3PES7_CELJU
          Length = 281

 Score =  235 bits (601), Expect = 9e-61,   Method: Composition-based stats.
 Identities = 99/257 (38%), Positives = 159/257 (61%), Gaps = 5/257 (1%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLA----EMGPQKLRVLDAGGGEGQ 57
           QDRNFDD+A++F +NIYG  KG +R A+L +D    L     +    + R+LDAGGG+GQ
Sbjct: 8   QDRNFDDLAKRFRKNIYGGLKGDVRLAVLERDCLACLPIAPFQQPGNRWRILDAGGGQGQ 67

Query: 58  TAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA-SHLETPVDLI 116
            ++++A  GH+V+LCD+SA+M+  A+       + D +  +H A QD+     +   D +
Sbjct: 68  FSLQLAAAGHEVVLCDISAEMLKLAEAHITHCQLQDRVTLVHAAIQDLPRVIDDHRFDFV 127

Query: 117 LFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKK 176
           + HAV+EW+ DP+S+L  L + L+P G LSL FYN H L+  N++  NF  +++     +
Sbjct: 128 ICHAVMEWMQDPQSLLPCLLNYLKPEGYLSLTFYNLHSLIYKNLLRTNFKKIRSRDYAGQ 187

Query: 177 KRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYC 236
           K +L+P  P  P QV  W+ E   Q++  +G+RVFHDY+ ++ ++      L+E+E  + 
Sbjct: 188 KGSLTPINPLMPEQVLQWVGELPLQLLSHSGIRVFHDYIFDEEKRERDPAGLVEMELLFS 247

Query: 237 RQEPYITLGRYIHVTAR 253
           +QEPY +LGRY H+  +
Sbjct: 248 QQEPYRSLGRYQHLLLQ 264


>UniRef50_Q2SJW8 SAM-dependent methyltransferase n=1 Tax=Hahella chejuensis KCTC
           2396 RepID=Q2SJW8_HAHCH
          Length = 264

 Score =  229 bits (585), Expect = 6e-59,   Method: Composition-based stats.
 Identities = 106/253 (41%), Positives = 160/253 (63%), Gaps = 2/253 (0%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQK-LRVLDAGGGEGQTAIKM 62
            NFD++ E+F  NIYGT KG+LR  ++ +DLD  LAE   +   R+LD G G    + ++
Sbjct: 11  HNFDELKERFQNNIYGTPKGRLRLDLINEDLDAHLAERLGEGAWRILDIGCGAAMISGRL 70

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQ-FIHCAAQDVASHLETPVDLILFHAV 121
           A+ GH++ L DLSA+M+  A+   E+ G +   + +     QDV   L+ P DLI+ HAV
Sbjct: 71  AQAGHRLTLTDLSAEMLTAARANLESLGSALACEEWREGPMQDVLPQLQGPYDLIIIHAV 130

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLS 181
           LEW+ DPR  L+   S LRPGGVLSL FYN +GL+  N++ GNF  ++      +K  L+
Sbjct: 131 LEWMDDPRPALELALSKLRPGGVLSLAFYNRNGLIYRNLLQGNFRKLKKNNWYYRKGGLT 190

Query: 182 PDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPY 241
           P  P DP +VY WL +A  +++ K G+R F+D++++   +   YE +LE+E  + ++EPY
Sbjct: 191 PQNPLDPDEVYNWLAQADMRLICKRGIRTFYDFMQKPVARERSYEDVLEMERMHSQKEPY 250

Query: 242 ITLGRYIHVTARK 254
           ++LGRYIHV  +K
Sbjct: 251 LSLGRYIHVLYQK 263


>UniRef50_Q1YTE5 Possible methyltransferase n=1 Tax=gamma proteobacterium HTCC2207
           RepID=Q1YTE5_9GAMM
          Length = 260

 Score =  227 bits (579), Expect = 3e-58,   Method: Composition-based stats.
 Identities = 98/251 (39%), Positives = 152/251 (60%), Gaps = 2/251 (0%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQ-KLRVLDAGGGEGQTAIK 61
           DRNFDD++EKF+R +YG  KG +R A++W+DL   L ++  Q  LR+LD GGG GQ  + 
Sbjct: 7   DRNFDDLSEKFARKVYGGLKGDIRLAVIWRDLLAALPDLEIQAPLRILDIGGGLGQLTVA 66

Query: 62  MAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
           +A+ GHQV+  DLS QM++ A++ A  +GV D + +     Q +        DL++ HA+
Sbjct: 67  LAKLGHQVVYNDLSQQMLEVAQKLALEEGVMDKIIWCQQPYQTLKDQGLERFDLVMSHAL 126

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLS 181
           +EW+A+P  ++  L   L P G+LSL FYN + L+  N++ GNF+ V  G      ++L+
Sbjct: 127 MEWLAEPELLIADLQQYLSPQGLLSLTFYNQNALVYRNLIRGNFN-VLQGEFSAHPKSLT 185

Query: 182 PDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPY 241
           P  P  P  V  W+++AG      +G+RVFHDY+  +    +   A++++E R+  QEP+
Sbjct: 186 PGEPLQPQAVQEWVDQAGLVTDYSSGIRVFHDYVTTQRGGHENASAVIDMELRHSVQEPF 245

Query: 242 ITLGRYIHVTA 252
             LGRYIH   
Sbjct: 246 KWLGRYIHFIC 256


>UniRef50_Q1ZIA5 SmtA protein n=2 Tax=Gammaproteobacteria RepID=Q1ZIA5_9GAMM
          Length = 256

 Score =  227 bits (578), Expect = 4e-58,   Method: Composition-based stats.
 Identities = 118/256 (46%), Positives = 165/256 (64%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M D NFD IA KF +NIYGTTKG++R A++WQ +   LA +  + LR+LDAGGG G  A 
Sbjct: 1   MIDHNFDGIAHKFLKNIYGTTKGKIRTAVVWQAILDCLALLPQRPLRILDAGGGCGFLAQ 60

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
           K+A  GHQV+LCD+S  ++D AK+  + K  + N+  IHC  Q ++ H++   DLIL HA
Sbjct: 61  KLAAMGHQVVLCDISKVLLDEAKKQMQGKDFAKNVHIIHCPIQQLSEHVDADFDLILNHA 120

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
           VLEW+  P+  LQ L ++L   GV+SLMFYN      HN++  NFD+V+ GM +KK   L
Sbjct: 121 VLEWLECPKQTLQGLLTLLNVNGVMSLMFYNKDAQRFHNLLCANFDFVERGMLRKKVVRL 180

Query: 181 SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP 240
           +P +P     V  WL+E  + ++ KTGVR+ HDYL++  Q    Y  LL +E +Y +QEP
Sbjct: 181 TPTHPLLEKDVQSWLKEVNFYVLQKTGVRIIHDYLKDPTQSVHKYAQLLAMEQKYNQQEP 240

Query: 241 YITLGRYIHVTARKPQ 256
           Y +LGRY H+  +  Q
Sbjct: 241 YASLGRYTHLMIKATQ 256


>UniRef50_A4XQ92 Methyltransferase type 11 n=17 Tax=Pseudomonas RepID=A4XQ92_PSEMY
          Length = 249

 Score =  221 bits (563), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 95/253 (37%), Positives = 143/253 (56%), Gaps = 6/253 (2%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M DR+FD++A +F+  IYG  KG +R A+L  DL   L     + LRVLD G G G  ++
Sbjct: 1   MSDRHFDELATRFAEKIYGGAKGAIRLAVLQADLAEAL---PDRPLRVLDVGAGLGHMSL 57

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
            +A RGH V L + +  M++ A+Q     G      FI    Q++   L+ P DL+L HA
Sbjct: 58  WLAGRGHDVTLAEPAEPMLEGARQRFAEAG--QRATFIQAPWQELLGRLDQPYDLVLCHA 115

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
           VLEW+A+P ++L  L  +   GG LSL FYN   L+  N++ G+F  ++      + ++L
Sbjct: 116 VLEWLAEPGAILPVLHQLTAKGGWLSLAFYNKDALIYRNLLKGHFRKLRKERFAGEGQSL 175

Query: 181 SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP 240
           +P  P DP ++   L E  WQ+  ++GVRVFHDY+ ++ Q +     LLE+E  + R   
Sbjct: 176 TPQRPLDPRELATQLGEH-WQVESRSGVRVFHDYMPQEFQAKAELIDLLEMELAHRRHPA 234

Query: 241 YITLGRYIHVTAR 253
           +  LGRY+H   R
Sbjct: 235 FAGLGRYLHWICR 247


>UniRef50_Q31JJ3 SAM-dependent methyltransferase n=3 Tax=Piscirickettsiaceae
           RepID=Q31JJ3_THICR
          Length = 259

 Score =  215 bits (549), Expect = 1e-54,   Method: Composition-based stats.
 Identities = 100/258 (38%), Positives = 152/258 (58%), Gaps = 8/258 (3%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIK 61
           QDRNFD + +KF + +Y T KG+ R  +L +DL  +       KL + DAG G  Q +  
Sbjct: 4   QDRNFDKLVDKFEKKVYDTVKGEWRLKLLKEDLTPL---KKGNKLSIWDAGCGFAQISQW 60

Query: 62  MAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
           +AE GH++ LCDLS QM+ RAK       +    +FI    Q+VA  +E   DL+LFHAV
Sbjct: 61  LAESGHRLTLCDLSHQMLLRAKANFAQADLFA--EFIEGPVQEVAKQIEPQ-DLVLFHAV 117

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFD--YVQAGMPKKKKRT 179
           LEW+A P   L+ +   ++PGG LSL+FYN + ++++N + G +   ++       K + 
Sbjct: 118 LEWLAQPEETLKIVTEQVKPGGYLSLLFYNRNSVVINNTLKGKWRLPFILEDAYLNKGKK 177

Query: 180 LSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQE 239
           L+P  P+ P  V  WL++ G++I   TG+RVFHDY+  +  ++   E L+ LE R+CR+ 
Sbjct: 178 LTPPNPQIPEVVCQWLQDWGFKIEIHTGIRVFHDYMTREVLEQSEMEDLMALEYRFCREP 237

Query: 240 PYITLGRYIHVTARKPQS 257
            Y  + RYIH+ A+K  S
Sbjct: 238 TYRNMARYIHILAKKKDS 255


>UniRef50_A4VI82 Methyltransferase, putative n=5 Tax=Pseudomonadaceae
           RepID=A4VI82_PSEU5
          Length = 360

 Score =  213 bits (544), Expect = 4e-54,   Method: Composition-based stats.
 Identities = 93/253 (36%), Positives = 144/253 (56%), Gaps = 6/253 (2%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M DR+FD++A +F+  IYG  KG +R A+L  DL  +L    P+ LRVLD G G G  ++
Sbjct: 112 MSDRHFDELATRFAEKIYGGAKGAIRLAVLQADLAEIL---PPRPLRVLDIGAGLGHMSL 168

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
            +A++GH V L + +  M+  A+Q     G      FI    Q+V +H++   DL++ HA
Sbjct: 169 WLAQQGHAVTLAEPAEPMLQGARQQFADAG--QQATFIQAPWQEVQAHVDGRFDLVICHA 226

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
           VLEW+A+P+++L  L  +    G LSL FYN   L+  N++ G+F  +++     ++++L
Sbjct: 227 VLEWLAEPQAILPVLHRLTAADGWLSLAFYNRDALIYRNLLKGHFKKLRSQTYAGERQSL 286

Query: 181 SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP 240
           +P  P DP ++   L    WQ+   +GVRVFHDY+    Q R     L+E+E  Y R   
Sbjct: 287 TPQQPLDPRELAAQLAPH-WQVEFSSGVRVFHDYMPADFQARTEPADLIEMELAYRRHPT 345

Query: 241 YITLGRYIHVTAR 253
           +  LGRY+H   R
Sbjct: 346 FAGLGRYLHWLCR 358


>UniRef50_C5BHU7 SAM-dependent methyltransferase n=1 Tax=Teredinibacter turnerae
           T7901 RepID=C5BHU7_TERTT
          Length = 263

 Score =  213 bits (543), Expect = 4e-54,   Method: Composition-based stats.
 Identities = 94/262 (35%), Positives = 155/262 (59%), Gaps = 8/262 (3%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEM-GPQKLRVLDAGGGEGQTA 59
           MQDRNFDD+A +F RN+YGT KG++R A+L +D      E+     L +LD G G+   +
Sbjct: 1   MQDRNFDDLAPRFKRNVYGTLKGRVRLAVLERDFREYAPELYADSPLDLLDLGAGQAPFS 60

Query: 60  IKMAERGHQVILCDLSAQMIDRAKQAAE--AKGVSDNMQFIHCAAQDVAS-----HLETP 112
           ++ A+ GH+++L D+S++M+  A+ A    A    + +  I    Q +A       L + 
Sbjct: 61  LQFAQLGHRLVLADISSEMLAGAQLAMADWAAEHRERVHAICHPLQQLAQPLRDMALPSA 120

Query: 113 VDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGM 172
            D+++ HAVLEW+A+P  +   L + L+PGG+LSL FYN +GL   N++  NF       
Sbjct: 121 FDVVICHAVLEWLAEPDRLYSHLANYLKPGGMLSLTFYNINGLAFKNLLRTNFHKFDIDN 180

Query: 173 PKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELE 232
            +  + +L+P +P++P  V   L + G++I+ ++G+RVFHDY+ +  ++    EA++  E
Sbjct: 181 FRSFRGSLTPTHPQEPHHVLRQLSKQGFEIVCRSGIRVFHDYILDPVERNREPEAIVGKE 240

Query: 233 TRYCRQEPYITLGRYIHVTARK 254
             Y R+E +  + RYIHV  RK
Sbjct: 241 LEYSRRESFWPIARYIHVLGRK 262


>UniRef50_UPI0000E11711 methyltransferase type 11 n=1 Tax=Glaciecola sp. HTCC2999
           RepID=UPI0000E11711
          Length = 256

 Score =  212 bits (541), Expect = 7e-54,   Method: Composition-based stats.
 Identities = 103/253 (40%), Positives = 145/253 (57%), Gaps = 8/253 (3%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
           D  FD I++KF++NIYGTTKGQLR A+L   L   L  +     ++LD+G G GQ A   
Sbjct: 10  DHGFDGISDKFAKNIYGTTKGQLRHALLCHHL-STLNLVNTPPKQILDSGCGLGQMAEFF 68

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
           A+ GH V   D+S++ I  AKQ A+ K +S  + +   + Q V        DLI+ HAVL
Sbjct: 69  ADAGHHVEGMDISSESIAYAKQQAQDKHLS--IDYSVGSLQSVTK----QYDLIINHAVL 122

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSP 182
           EW+ +P + ++ L   L PGG LSL F+N   L   N++ GNFDYV+ G+  KKK  L+P
Sbjct: 123 EWLQEPFAAIELLLKQLVPGGHLSLSFFNKDALTFGNLIYGNFDYVKKGLKVKKKVRLNP 182

Query: 183 DYPRDPAQVYLWLEE-AGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPY 241
             P     V  ++      +I+ + G+R  HDY+R+   Q   YEALL+ E  Y  Q PY
Sbjct: 183 QQPLSVQPVLSFINSLNNIEIIHQAGIRCIHDYMRDLSHQTTHYEALLDAEITYSTQPPY 242

Query: 242 ITLGRYIHVTARK 254
           + LG+Y H+  RK
Sbjct: 243 MWLGKYFHLVLRK 255


>UniRef50_Q15TU3 Methyltransferase type 11 n=1 Tax=Pseudoalteromonas atlantica T6c
           RepID=Q15TU3_PSEA6
          Length = 252

 Score =  212 bits (540), Expect = 9e-54,   Method: Composition-based stats.
 Identities = 95/253 (37%), Positives = 141/253 (55%), Gaps = 8/253 (3%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIK 61
           +D+NFD IA+KF +NIYGTTKG+LR  +L   L + +          LDAGGG G+ +  
Sbjct: 6   RDQNFDAIADKFEKNIYGTTKGRLRHELLQYHLRKNIDFSTLSIA--LDAGGGTGEMSRV 63

Query: 62  MAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
           + + G  V L D+S + +  AKQ       S  +  IH     +    +   DL++ HAV
Sbjct: 64  LLQSGVNVTLSDISNEALAIAKQKCSE---SSALSVIHSDILGLP---DCEYDLVICHAV 117

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLS 181
           LEW+ DP   ++ L S+ + GG  SL F+N    ++ N++ GNFDYV+ GM  K +  LS
Sbjct: 118 LEWLNDPYVNVRKLISMTKIGGYFSLTFFNKDAQMLGNLLYGNFDYVKQGMKVKNRVRLS 177

Query: 182 PDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPY 241
           P+ P  P  V  +L++    I+   G+R FHDYL++   Q   YE L E E  +  +EPY
Sbjct: 178 PNKPLQPRAVIDFLQKQPVSIISTAGIRCFHDYLKDPTMQLSHYEQLKEAEMAFGDKEPY 237

Query: 242 ITLGRYIHVTARK 254
           + LG+Y H+  R+
Sbjct: 238 MWLGKYFHILMRR 250


>UniRef50_Q21JL0 Methyltransferase type 12 n=1 Tax=Saccharophagus degradans 2-40
           RepID=Q21JL0_SACD2
          Length = 262

 Score =  211 bits (538), Expect = 2e-53,   Method: Composition-based stats.
 Identities = 94/265 (35%), Positives = 142/265 (53%), Gaps = 13/265 (4%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMG-PQKLRVLDAGGGEGQTA 59
           M DRNFDD+A +F+RNIYG+ KG++R  +L +DL   +        + VLD G G+G  +
Sbjct: 1   MADRNFDDLAPRFARNIYGSHKGRVRLEVLKRDLCDYVPLFQNLAGVEVLDMGAGQGHFS 60

Query: 60  IKMAERGHQVILCDLSAQMIDRAKQAAEA---------KGVSDNMQFIHCAAQDVASHLE 110
           + +AE+G  V LCD+S +M+  AK   +            +  +  F  CA Q +     
Sbjct: 61  LGLAEQGAHVHLCDVSEKMLAMAKVRWQEICEAQAQAGMPIVGSATFTQCALQQLPV--- 117

Query: 111 TPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQA 170
               L+L HAVLEW+ DPR     L   +  GG LS++ YNAHGL   N++ GNF     
Sbjct: 118 KEYPLVLGHAVLEWLEDPRQGFGYLVDSVATGGYLSVIVYNAHGLAFKNLLRGNFKKFDR 177

Query: 171 GMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLE 230
              K  K +L+P  P  P Q+  W ++   +++G +G+RVF DY+ +K  +    + LL 
Sbjct: 178 NNFKAFKGSLTPISPLTPEQLMQWGKKLKLELVGFSGIRVFQDYILDKSIREADPDGLLV 237

Query: 231 LETRYCRQEPYITLGRYIHVTARKP 255
            E  Y R EP+  + RY+H   ++P
Sbjct: 238 KELEYSRLEPFRNMARYLHFVFKRP 262


>UniRef50_B4RYI5 SAM-dependent methyltransferase n=2 Tax=Alteromonas macleodii
           RepID=B4RYI5_ALTMD
          Length = 247

 Score =  207 bits (528), Expect = 2e-52,   Method: Composition-based stats.
 Identities = 94/253 (37%), Positives = 139/253 (54%), Gaps = 9/253 (3%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIK 61
            D  FD IAEKF+ NIYGTTKG+LR  +L   L   LA    + L+ ++ GGG G     
Sbjct: 3   NDHIFDGIAEKFANNIYGTTKGRLRHTLLCDVLAPYLA----RPLKAIEIGGGTGVMTAH 58

Query: 62  MAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
           +A  GH V+L D S+ ++ +A   A     SDN++  H   Q++        DL++ HAV
Sbjct: 59  IAAMGHDVVLTDASSDVLSKA---APLLNASDNIRIRHQYLQEIDDL--AAYDLVVCHAV 113

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLS 181
           LEW+  P   +  +   ++ G  LSL F+N    L  N + GNFDY+  GM  KK+  L+
Sbjct: 114 LEWLDAPFDAIDFIHKNMKRGARLSLSFFNQDANLFANAIYGNFDYIAKGMKAKKQVRLN 173

Query: 182 PDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPY 241
           P  P    +V  + E  G++++ K G+R FHDY+R+   Q   ++ LL LE +Y +  PY
Sbjct: 174 PKQPLGAMRVVDYCESLGFKVLDKAGIRCFHDYMRDISHQNSKFDELLALERQYHKMPPY 233

Query: 242 ITLGRYIHVTARK 254
           + LG+Y H+   K
Sbjct: 234 LWLGKYFHLILEK 246


>UniRef50_Q1QA01 Methyltransferase type 11 n=4 Tax=Moraxellaceae RepID=Q1QA01_PSYCK
          Length = 295

 Score =  204 bits (520), Expect = 2e-51,   Method: Composition-based stats.
 Identities = 93/263 (35%), Positives = 150/263 (57%), Gaps = 10/263 (3%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMG---PQKLRVLDAGGGEGQT 58
            DR+FD IA+ F + +YG  KG +R A+L +DL    A+      + LR+LD G G  Q 
Sbjct: 31  TDRSFDAIADHFEKKVYGGLKGDIRLAVLRRDLFEYCAQTSHKLGRPLRILDVGAGLAQI 90

Query: 59  AIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSD---NMQFIHCAAQDVAS-HLE--TP 112
           AI++A +GH +++ D+SA M+D+A++ A     +D   N+ +  C  Q++     +    
Sbjct: 91  AIELATQGHILVINDISANMLDKAQERAAQSSANDEKLNITWYVCPYQELEEKLADKTEK 150

Query: 113 VDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGM 172
            DLI+ HA+LEW+A+P +V+      L   G LSL FYN       N++ GNF+ +    
Sbjct: 151 FDLIMCHALLEWLAEPAAVMDFFDQQLSDNGALSLCFYNPASFDYRNLIMGNFNLLDNTE 210

Query: 173 PKKK-KRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLEL 231
            K   K++L+P++P    +V  WL+   +Q +  +G+RVFHDY   K    +  EA++ +
Sbjct: 211 YKADSKKSLTPNHPVAKEEVEAWLQAHDYQTLIASGLRVFHDYSPLKRGGHNDPEAVIRM 270

Query: 232 ETRYCRQEPYITLGRYIHVTARK 254
           E RY + +PY  LGRY+H+ A +
Sbjct: 271 ELRYSQLDPYKWLGRYLHLLATR 293


>UniRef50_A5EV89 S-adenosylmethionine-dependent methyltransferase n=2
           Tax=Cardiobacteriaceae RepID=A5EV89_DICNV
          Length = 268

 Score =  202 bits (514), Expect = 1e-50,   Method: Composition-based stats.
 Identities = 79/255 (30%), Positives = 132/255 (51%), Gaps = 5/255 (1%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
             F++I + F + IY   KG++R A+L +DL   +    P+ L +LD G G GQ A+  A
Sbjct: 15  HYFEEIGDHFLKQIYYNNKGRIRLAVLKRDLAPFMR--TPKPLEILDIGAGAGQMALWCA 72

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVAS-HLETPVDLILFHAVL 122
             GH+V L D S +++ +A++ A+ + ++    FI      +         D +L HAVL
Sbjct: 73  AFGHRVTLFDASERLLAQAQKQAQKESLNAQCTFICGEITQMPDVLGARQFDFVLSHAVL 132

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSP 182
           EW+ D   + +     L+P G+LSLM+YN   L     V GNF YV +G+  KK   L+P
Sbjct: 133 EWLEDGAQLFERCQQYLKPNGLLSLMYYNRSALEFIQHVFGNFSYVDSGLVAKKTAKLTP 192

Query: 183 DYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPYI 242
            YPR    V   L      +  ++G+R F+DY++ + +  +  E+++  E     +  ++
Sbjct: 193 KYPRSSDWVAAQLGA--LPLKKQSGIRCFYDYMKPEDRAANSIESIIAHELSLSLRREFL 250

Query: 243 TLGRYIHVTARKPQS 257
            + RYIH   ++  S
Sbjct: 251 PVARYIHEIRQRTIS 265


>UniRef50_Q1QUF1 SmtA protein n=1 Tax=Chromohalobacter salexigens DSM 3043
           RepID=Q1QUF1_CHRSD
          Length = 268

 Score =  198 bits (505), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 99/258 (38%), Positives = 139/258 (53%), Gaps = 9/258 (3%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIK 61
           +DR FD +A+KF+  +YGT +G +R A+L   L R L          LD G G GQ +  
Sbjct: 16  RDRVFDGLADKFAAGLYGTPRGAIRLAVLEHVLPRELPADARP---ALDVGAGLGQMSEW 72

Query: 62  MAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
           +A RGH V L + S  M +RA            +  +    Q +A     P  LI+ HAV
Sbjct: 73  LARRGHAVTLVEPSRDMRERAMDRVAGLA----VTALDATWQTLAERAPGPWGLIVCHAV 128

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQ--AGMPKKKKRT 179
           LEW+A+PR     L S+L PGG LS+M +N   L   N+V GN             K++ 
Sbjct: 129 LEWLAEPRDAFARLASLLAPGGYLSVMVFNRDALRFSNVVKGNLAKALDDRLEGLGKRQR 188

Query: 180 LSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQE 239
           L+P  P   AQV  W +EAG  ++  TGVR+FHDYL ++    +  + L+ELE RYC+Q+
Sbjct: 189 LTPISPLTDAQVRAWSQEAGLSLVSVTGVRIFHDYLADRDVSPEKLDQLIELECRYCQQD 248

Query: 240 PYITLGRYIHVTARKPQS 257
           P+  LGRY+H T  KP++
Sbjct: 249 PHWRLGRYLHYTLFKPET 266


>UniRef50_Q1N5H2 SAM-dependent methyltransferase n=1 Tax=Bermanella marisrubri
           RepID=Q1N5H2_9GAMM
          Length = 258

 Score =  195 bits (496), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 88/258 (34%), Positives = 139/258 (53%), Gaps = 8/258 (3%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
           DRNF+ ++ +F   IYGT KGQ+R A+L +DL   + +     L +LD G G+GQ +  +
Sbjct: 2   DRNFNGLSNRFKNQIYGTLKGQMRLALLEKDLSPYIEQT--HALNILDCGAGQGQFSSML 59

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQ-FIHCAAQDVASHL-----ETPVDLI 116
           A+ GH ++L D+S +M+  A+         +     I    Q +   L      T  DL+
Sbjct: 60  AQHGHSLVLNDVSDEMLAMAQANLAELAPDNQTHQMITAPLQSLNEELHTRALPTQYDLV 119

Query: 117 LFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKK 176
           L HAVLEW+ +P + ++ L   ++  G+LSLMFYN H ++  N++ G++   Q       
Sbjct: 120 LNHAVLEWLHEPFAAIEQLALWVKSDGILSLMFYNLHAIVWRNLMNGSWQRAQNTHFHHD 179

Query: 177 KRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYC 236
           K  L P  P +PA V   +E  G+ I    G+R  HD++  + ++R   E  +ELE+   
Sbjct: 180 KNNLMPQNPLNPADVVEKIESLGFSIELHRGIRCVHDHMFVEMRKRKTLEEFVELESDIG 239

Query: 237 RQEPYITLGRYIHVTARK 254
            + PY  LGRY+H+ ARK
Sbjct: 240 LKAPYRDLGRYVHIVARK 257


>UniRef50_Q2NUA0 Putative S-adenosylmethionine-dependent methyltransferase n=1
           Tax=Sodalis glossinidius str. 'morsitans'
           RepID=Q2NUA0_SODGM
          Length = 199

 Score =  187 bits (476), Expect = 3e-46,   Method: Composition-based stats.
 Identities = 114/194 (58%), Positives = 143/194 (73%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           +QDRNFDDIA+KF+RNIYGTTKG++RQA+LWQDL  +LA +  + L +LDAGGGEG+ A 
Sbjct: 2   IQDRNFDDIADKFARNIYGTTKGKIRQAVLWQDLQTLLAHLPQRPLCILDAGGGEGRIAA 61

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
           ++A  GH V+LCDLSAQMI RA+Q A+  GV    + +  A QD+ +HLE   DLIL HA
Sbjct: 62  QLATLGHDVVLCDLSAQMIHRAQQQAKTLGVEQRFRCVQSAIQDIGTHLERHADLILCHA 121

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
           VLEWVA P ++LQ L   L   G LSLMFYN HGL++ NM+ GN  +V AGMPK+KKR+L
Sbjct: 122 VLEWVAQPEALLQILNQCLAGDGALSLMFYNKHGLVIRNMLLGNMAFVAAGMPKRKKRSL 181

Query: 181 SPDYPRDPAQVYLW 194
            PD+P DPA    W
Sbjct: 182 MPDHPCDPADWKKW 195


>UniRef50_B5L6J9 Methyltransferase n=1 Tax=Micromonospora chalcea RepID=B5L6J9_MICCH
          Length = 263

 Score =  181 bits (459), Expect = 3e-44,   Method: Composition-based stats.
 Identities = 69/262 (26%), Positives = 127/262 (48%), Gaps = 11/262 (4%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           +++  FD+   +F +    T  G+LR +++  ++ R    +G + LRVLD  GG G+ A+
Sbjct: 5   IENALFDERLAQF-QQWQKTPWGRLRYSVVEANVAR---HLGDRPLRVLDVAGGNGRDAV 60

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVAS-HLETPVDLILFH 119
            +A RGH V + D +   +  A++ A  +GV++ ++     A DV         DL+L H
Sbjct: 61  PIAARGHHVTVLDSAPVSLAMAQRLAADEGVAERIEIREGDAHDVPELFAGQEFDLLLCH 120

Query: 120 AVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAG-NFDYVQAGMPKKKKR 178
            +L++VADP  V++ L  VL+PGG LS++  NA+ + +   V   + D     +  + K+
Sbjct: 121 NLLQYVADPAVVIRGLVKVLKPGGSLSVVGPNAYAVPLEAAVRELDLDAALRAVTARTKQ 180

Query: 179 TLSPDY---PRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQ--QRDCYEALLELET 233
                         Q+   L ++G +I+G  GV    + + +       + +  L +LE 
Sbjct: 181 VPVYGRDVAVLTADQIGADLRDSGLEIVGHYGVINICNVIADNDVKSDPEFFARLEKLEL 240

Query: 234 RYCRQEPYITLGRYIHVTARKP 255
               + PY    R  H+  ++P
Sbjct: 241 ALADRMPYPLTARNFHLVGQRP 262


>UniRef50_C8SD34 Methyltransferase type 11 n=1 Tax=Ferroglobus placidus DSM 10642
           RepID=C8SD34_FERPL
          Length = 246

 Score =  181 bits (459), Expect = 3e-44,   Method: Composition-based stats.
 Identities = 46/233 (19%), Positives = 95/233 (40%), Gaps = 21/233 (9%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
           R +D  +  +  +      G      +W+++   LAE+   K+R+LD G G G  A+ +A
Sbjct: 10  RYWDYRSRDYDLSP-----GHSGLPEVWKEV---LAEIFEDKMRILDVGTGTGFLAVILA 61

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
           E GH+V+  D+S +M+  A++ A  KGV   + F    A+++    +   D  +   VL 
Sbjct: 62  ELGHEVVGIDISEEMLKVARRKAVDKGV--RIDFRVGDAENLP-FDDEEFDAAVCRHVLW 118

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAH----GLLMHNMVAGNFDYVQAGMP------ 173
            + +P   +     V++ GG + ++  N        L   +        +  +P      
Sbjct: 119 TLPNPERAISEWKRVVKKGGKVVIIDGNWEHGILATLKRLLGKAGMVIFEGKLPKNNSYS 178

Query: 174 KKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYE 226
           K+ K+ L         +V+  +++AG   +    +      + +       + 
Sbjct: 179 KEVKKALPCYGSLTEEKVFELMKKAGLSRISIRDLTWIRKLILKNRPAYYRFA 231


>UniRef50_B9K8U5 Ubiquinone/menaquinone biosynthesis methyltransferase-related
           protein n=6 Tax=Thermotogaceae RepID=B9K8U5_THENN
          Length = 258

 Score =  179 bits (455), Expect = 8e-44,   Method: Composition-based stats.
 Identities = 57/258 (22%), Positives = 108/258 (41%), Gaps = 25/258 (9%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
            +  IA+++  ++Y T K +L   +    +   L+E      RVLD GGG G+ ++ + E
Sbjct: 8   YYSRIAKEYD-SMYETPKWRLYHRL----IQSFLSEHLKVPCRVLDLGGGTGRWSLFLLE 62

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA-VLE 123
           RG  V L D S +M+  A++     GV    +F+   A+D+        D +L    VL 
Sbjct: 63  RGFDVTLVDPSEEMLKIAEKK----GVK---KFLKARAEDLP-FSSHSFDTVLAMGDVLS 114

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMP-----KKKKR 178
           +V +       +  VL+PGG+L     N +  L H +    ++ +   +           
Sbjct: 115 YVENKVKAFSEIARVLKPGGLLIATVDNFYTFLQHMIEENTWEKIPRFLKTQTIEVGNTL 174

Query: 179 TLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQ 238
                Y   P  +       G+  +   G+ VF DY  ++ ++++    + ELE  + R 
Sbjct: 175 FSFNSYAFRPEDIESI---EGFDTIEVRGIGVF-DYSEDQVRKKEDL--IFELEKEFSRD 228

Query: 239 EPYITLGRYIHVTARKPQ 256
              +    ++    +K +
Sbjct: 229 RAILWRAEHVFFVLKKKE 246


>UniRef50_B0U3W1 3-demethylubiquinone-9 3-methyltransferase n=7 Tax=Xylella
           fastidiosa RepID=UBIG_XYLFM
          Length = 246

 Score =  178 bits (453), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 51/203 (25%), Positives = 83/203 (40%), Gaps = 6/203 (2%)

Query: 7   DDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERG 66
           D  A   S         +   A+    LD +   +     RVLD G G G  +  +A +G
Sbjct: 18  DKFAAFTSGWWDPHGPQKPLHALNPVRLDYISKRVSLSGARVLDVGCGGGLLSEALARQG 77

Query: 67  HQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVA 126
             V   DL+ ++I  A+      G+   + +   A +D+ +    P D I    +LE V 
Sbjct: 78  AHVTAIDLAPELIKAARLHGLESGI--QVDYRIQAIEDLLAEQPAPFDAIACMEMLEHVP 135

Query: 127 DPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPR 186
           DP +++     +L+PGG L +   N         V G  +YV   +PK   +        
Sbjct: 136 DPAAIVDACAHLLKPGGRLFVSTINRTLAAFMLAVVGA-EYVVRLLPKGTHQYKD---FI 191

Query: 187 DPAQVYLWLEEAGWQIMGKTGVR 209
            PA++  WL  AG  +   +G+R
Sbjct: 192 RPAELAAWLRHAGLHLEDVSGMR 214


>UniRef50_C9R8S5 Methyltransferase type 11 n=1 Tax=Ammonifex degensii KC4
           RepID=C9R8S5_AMMDK
          Length = 225

 Score =  176 bits (447), Expect = 6e-43,   Method: Composition-based stats.
 Identities = 48/212 (22%), Positives = 84/212 (39%), Gaps = 22/212 (10%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           FD  A  +    Y T +G+L   + W+ L ++L+       +VLDAG G G  +  +A  
Sbjct: 4   FDAYATHYED-WYATPRGRLVWELEWRCLQKLLSL--RPGEKVLDAGCGTGVVSRALAAA 60

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV 125
           G +V   D+S  M+  A++     G   N+ ++      +    +   D ++    LE+V
Sbjct: 61  GAEVTGIDISPAMLAVAREK----GAGGNIVYLEGDMSSLP-FPDASFDAVVCFTALEFV 115

Query: 126 ADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYP 185
           A+P   L+ +W VL+PGG L +   N                      +K K   +  + 
Sbjct: 116 AEPERALEEMWRVLKPGGRLLVGVLNHRSSWARR--------------RKGKGVFAHAHF 161

Query: 186 RDPAQVYLWLEEAGWQIMGKTGVRVFHDYLRE 217
               ++   L +     +   GV  F   L  
Sbjct: 162 YSVRELEQLLRKLNPCRVKWQGVIYFPPELPS 193


>UniRef50_Q1QEI9 3-demethylubiquinone-9 3-methyltransferase n=59 Tax=Proteobacteria
           RepID=UBIG_PSYCK
          Length = 257

 Score =  176 bits (447), Expect = 7e-43,   Method: Composition-based stats.
 Identities = 48/216 (22%), Positives = 85/216 (39%), Gaps = 16/216 (7%)

Query: 6   FDDIAEKFSRNIYGTTKGQ----LRQAILWQDLDR--------VLAEMGPQKLRVLDAGG 53
           F+ +A ++               LR   + +++ R          AEMG    +VLD G 
Sbjct: 19  FNKLAGEWWNKTGAFATLHEINPLRLNWIEENVKRGYVSADSQKTAEMGLAGKKVLDVGC 78

Query: 54  GEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPV 113
           G G  +  MA RG  V   DL  + +  A   AE   + D +++ H   + +A+      
Sbjct: 79  GGGILSESMARRGADVTGIDLGTENLKAASLHAEQSNLQDTLRYQHIPVEALAATHAGQF 138

Query: 114 DLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMP 173
           D++    +LE V DP +++   + +L PGGV  L   N +       + G  +YV   + 
Sbjct: 139 DVVTCMEMLEHVPDPAAIVDACFKLLAPGGVCVLSTINRNPKSYLFAIVGA-EYVLRLLD 197

Query: 174 KKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVR 209
           +             PA++     +A +      G+ 
Sbjct: 198 RGTHDY---AKFITPAELDKMAIDAEFARQDIIGLH 230


>UniRef50_Q46F96 Ubiquinone/menaquinone biosynthesis methyltransferase n=2
           Tax=Methanosarcina RepID=Q46F96_METBF
          Length = 259

 Score =  175 bits (443), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 51/230 (22%), Positives = 100/230 (43%), Gaps = 21/230 (9%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
            + +D  ++ +         G + ++ +W  L  +   +GP    VLD G G G  A+ +
Sbjct: 17  KKYWDYGSKFYDTAPGN---GGVEESQMWSKL--LSGAIGPGPKNVLDVGSGTGIIAMYL 71

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
           AE GH+V   D S  M+D A++ A  KG   N++F+    +++ +  +   D I    VL
Sbjct: 72  AELGHRVTAVDFSEGMMDVARKKALEKG--ANIRFMEMDVENL-NFEDETFDFITARYVL 128

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSP 182
             ++ P   ++    V++PGG + ++        +   ++  F+Y      K  K   + 
Sbjct: 129 WTMSHPEKAVKEWVRVVKPGGRIVIIDGKWVTKGLLPCIS-AFNYHIYRFIKYGKNPFTY 187

Query: 183 DY-------PRDPA-----QVYLWLEEAGWQIMGKTGVRVFHDYLREKHQ 220
           DY         +P      QV  ++ +AG   +  T +++  D  R++  
Sbjct: 188 DYKKDINVSLPNPHGVESKQVVEYMSKAGLDDIAVTDLKIIRDIQRKRLP 237


>UniRef50_D1JEE5 Putative uncharacterized protein n=1 Tax=uncultured archaeon
           RepID=D1JEE5_9ARCH
          Length = 253

 Score =  174 bits (442), Expect = 3e-42,   Method: Composition-based stats.
 Identities = 45/246 (18%), Positives = 92/246 (37%), Gaps = 19/246 (7%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
            +D  ++ + RN+Y   K Q      W+ + +       + L +LD G G G  A+  AE
Sbjct: 15  YWDRRSQTYDRNVY---KSQNAAEHFWKSILKT-EIGTDRNLNILDVGTGTGFLALLFAE 70

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
            GH+V   D+S  M+++++  A  + ++  + F+H  A+++    +   D+++   +L  
Sbjct: 71  LGHKVTGIDISKSMLEKSRCNAYKQKLA--VNFMHGDAENLP-FDDGSFDIVMNRYLLWT 127

Query: 125 VADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFD------------YVQAGM 172
           + DP++ +     V++ GG L L+    H   +H  +                  + A  
Sbjct: 128 LPDPKTAVNEWSRVVKSGGKLILIDGRWHDPAIHMRLRRFLASMIVLLTENRNPRMFASH 187

Query: 173 PKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELE 232
               K  L       P  V     E G + +    +     +  +             L 
Sbjct: 188 YATIKDQLPFFNGITPNDVVDLFTEVGLKKISVNNLEKLRAFETKNRPLSYKIANSPYLF 247

Query: 233 TRYCRQ 238
                +
Sbjct: 248 LALGEK 253


>UniRef50_B3TMR6 SAM-dependent methyltransferase n=1 Tax=Actinomadura kijaniata
           RepID=B3TMR6_9ACTO
          Length = 260

 Score =  174 bits (441), Expect = 3e-42,   Method: Composition-based stats.
 Identities = 68/258 (26%), Positives = 118/258 (45%), Gaps = 11/258 (4%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
           +FD     F +    T  GQLR +++  +L R    +G + LRVLD  GG G+ A+++A 
Sbjct: 6   HFDHRLANF-QQWQETPWGQLRYSVVEANLAR---HLGDRPLRVLDVAGGNGRDAVRLAL 61

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVAS-HLETPVDLILFHAVLE 123
           RGH V + D +   +  A++ A  +GV+D ++     A DV     +   DL+L H +L+
Sbjct: 62  RGHHVTVLDSAPISLAGAEELAAERGVADRIEVREGDAHDVPELFPDQDFDLLLCHNLLQ 121

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAG-NFDYVQAGMPKKKK---RT 179
           +V D   V++ +   LRPGG+LS++  NA  + +   V   + D     +    K     
Sbjct: 122 YVPDRAVVVRAIARRLRPGGLLSVVGPNAVAVPLEAAVRELDLDAALRAVDSSTKPNQVY 181

Query: 180 LSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQ--QRDCYEALLELETRYCR 237
            +        ++     +AG  ++G  GV      + +       + +  L +LE     
Sbjct: 182 GADVPVLTADEIGGHFRDAGLDVVGHHGVLSVCHLIADNEIKYDPEFFARLEKLEHTLAE 241

Query: 238 QEPYITLGRYIHVTARKP 255
           + PY +  R  H+  R P
Sbjct: 242 RAPYPSTARMFHLVGRLP 259


>UniRef50_B8HNX7 Ubiquinone biosynthesis O-methyltransferase n=1 Tax=Cyanothece sp.
           PCC 7425 RepID=B8HNX7_CYAP4
          Length = 258

 Score =  174 bits (441), Expect = 3e-42,   Method: Composition-based stats.
 Identities = 41/207 (19%), Positives = 75/207 (36%), Gaps = 9/207 (4%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
           + +D  A  +                 +      LA    Q  RVLD G G G     MA
Sbjct: 7   KYYDLRASTWWEEGQVLHLSNHFNQTRFTYASNHLANW--QNCRVLDVGCGGGLACEFMA 64

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
             G +V   D S   I  A++ A+   +   + +    A+D+  + +   D ++   VLE
Sbjct: 65  RLGARVSGMDRSKNSIQIAQEHAKQSEL--QINYQQGNAEDLP-YQQNSFDCVVCFDVLE 121

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPD 183
            V +   V+  ++ VL+PGG+      N        ++    + +   +P+         
Sbjct: 122 HVYNRNRVISEIYRVLKPGGIFFFDTINRTFQS-KLVMIWLLENILRQLPQGLHDW---H 177

Query: 184 YPRDPAQVYLWLEEAGWQIMGKTGVRV 210
               P ++   L + G+  +   G  V
Sbjct: 178 NFIQPHELEKILRDLGFIQIELKGFDV 204


>UniRef50_Q9NZJ6 Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial n=30
           Tax=Euteleostomi RepID=COQ3_HUMAN
          Length = 369

 Score =  173 bits (438), Expect = 6e-42,   Method: Composition-based stats.
 Identities = 43/214 (20%), Positives = 80/214 (37%), Gaps = 13/214 (6%)

Query: 4   RNFDDIAEKFSRN----IYGTTKGQLRQAILWQDLDRVLAEMGPQ----KLRVLDAGGGE 55
           + F  +A K+           +   LR   +  +L + +    P      +++LD G G 
Sbjct: 98  KTFLALAHKWWDEQGVYAPLHSMNDLRVPFIRDNLLKTIPNHQPGKPLLGMKILDVGCGG 157

Query: 56  GQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSD-NMQFIHCAAQDVASHLETPVD 114
           G     +   G  VI  D   + I  A+       V D  +++  C+ +++        D
Sbjct: 158 GLLTEPLGRLGASVIGIDPVDENIKTAQCHKSFDPVLDKRIEYRVCSLEEIVEETAETFD 217

Query: 115 LILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPK 174
            ++   V+E V D  + LQ    VL+PGG L +   N   L     +  + + +   +PK
Sbjct: 218 AVVASEVVEHVIDLETFLQCCCQVLKPGGSLFITTINKTQLSYALGIVFS-EQIAGIVPK 276

Query: 175 KKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
                 + +    P  +   LE  G  +    G+
Sbjct: 277 GTH---TWEKFVSPETLESILESNGLSVQTVVGM 307


>UniRef50_B3S9Y1 Putative uncharacterized protein n=1 Tax=Trichoplax adhaerens
           RepID=B3S9Y1_TRIAD
          Length = 302

 Score =  173 bits (438), Expect = 7e-42,   Method: Composition-based stats.
 Identities = 46/224 (20%), Positives = 87/224 (38%), Gaps = 18/224 (8%)

Query: 6   FDDIAEKFS----RNIYGTTKGQLRQAILWQDL------DRVLAEMGPQKLRVLDAGGGE 55
           F DIA K+     +N+       +R  ++   L       ++         ++LD G G 
Sbjct: 57  FSDIASKWWQWNNKNMPLHALNMVRVPLIRDALLGDEKSHKIDQPRPLSGYKILDVGCGG 116

Query: 56  GQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKG-VSDNMQFIHCAAQDV-ASHLETPV 113
           G     +A  G QV   D S+++I+ AK  A     V+ N+ +     + +  +      
Sbjct: 117 GILCEPLARLGAQVTGIDASSEIINVAKAHASKCDRVAANVSYQCTTIEQLTTTENAQSF 176

Query: 114 DLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMP 173
           D ++   V+E V +    + +   +++PGG   +   N   L    M+ G  +Y+   +P
Sbjct: 177 DAVIASEVIEHVDNVDLFVSSCCQLIKPGGKHIVTTINRTPLSYAVMIIGG-EYISRIIP 235

Query: 174 KKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLRE 217
                         P ++   LEE G  +    G+  F++ L  
Sbjct: 236 AGSHDW---KKFITPKELTKKLEEGGLNVDFIGGI--FYNPLTN 274


>UniRef50_Q21UL3 3-demethylubiquinone-9 3-methyltransferase n=5 Tax=Proteobacteria
           RepID=UBIG_RHOFD
          Length = 252

 Score =  172 bits (437), Expect = 9e-42,   Method: Composition-based stats.
 Identities = 45/224 (20%), Positives = 88/224 (39%), Gaps = 9/224 (4%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           F D+A ++        + +    I    L+ +         +VLD G G G  A  MA  
Sbjct: 27  FSDLAHRWWDL---EGEFRPLHQINPLRLEWINHLCPVAGQQVLDVGCGGGILADSMARL 83

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV 125
           G QV   DL+++ +  A+  A     + N+Q+   + + +A+      D++    +LE V
Sbjct: 84  GAQVTGIDLASKALRVAQLHALEAQ-TPNLQYQEISVEALAAQQPGSFDVVTCMEMLEHV 142

Query: 126 ADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYP 185
            DP SV++   ++++PGG +     N         + G  +YV   +P+           
Sbjct: 143 PDPASVVRACATLVKPGGWVFFSTLNRSPKSFVLAIVGA-EYVLNLLPRGTHEY---AKM 198

Query: 186 RDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALL 229
             P+++  +       +    G++ ++   R      D     L
Sbjct: 199 IRPSELASYCRSVELDLRHTRGMQ-YNPLTRRYWMSDDTSVNYL 241


>UniRef50_D1JD55 Putative uncharacterized protein n=1 Tax=uncultured archaeon
           RepID=D1JD55_9ARCH
          Length = 263

 Score =  172 bits (436), Expect = 1e-41,   Method: Composition-based stats.
 Identities = 41/227 (18%), Positives = 90/227 (39%), Gaps = 18/227 (7%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
            +D     +       +K + ++A     L       G  +  VLD G G G  ++ +A+
Sbjct: 18  YWDGRGRFYDSVPGHGSKEKEKRA----WLMEFKNVFGENRKNVLDVGTGTGFLSLLLAD 73

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
            GH+V   D+S  M+  AK+ A   G+   + F    A+++        D ++   +L  
Sbjct: 74  FGHEVTGIDMSEGMLSVAKEKAHDMGL--KIHFERGDAENLP-FDGQTFDCVVCRHLLWT 130

Query: 125 VADPRSVLQTLWSVLRPGGVLSLMF----------YNAHGLLMHNMVAGNFDYVQAG-MP 173
           + +P   +     V + GG ++++            +  G ++H M+    + V++   P
Sbjct: 131 LPNPEKAISEWIRVTKQGGKIAVIDGVWDRGIGRYLSRVGWILHVMITEKRNPVKSYHYP 190

Query: 174 KKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQ 220
           K+ +  L      D  ++  +L   G + +  T +    +  ++   
Sbjct: 191 KEVRDKLPYVKGIDGEEIASFLSNFGLKEISVTDLGYIREIQKKYLP 237


>UniRef50_C0Q9K2 UbiG n=1 Tax=Desulfobacterium autotrophicum HRM2 RepID=C0Q9K2_DESAH
          Length = 232

 Score =  171 bits (434), Expect = 2e-41,   Method: Composition-based stats.
 Identities = 51/225 (22%), Positives = 88/225 (39%), Gaps = 10/225 (4%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           FDD A  +        + +    I    L+ ++ +      RVLD G G G    K+A++
Sbjct: 13  FDDFATDWWDAN---GRMKSLHDINPLRLEYIMQQTDLTGKRVLDVGCGGGILTEKIAQQ 69

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV 125
               I  D SA+M   A+  A+   +  ++ +I    + +    +T  D+IL   +LE V
Sbjct: 70  AGATIGIDASAEMTAIARTHAKQSNL--DILYIDTDIEHLTRFTQTGFDVILCMELLEHV 127

Query: 126 ADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYP 185
               SV+      L PGG++     N + +     V    +YV   +PK      S    
Sbjct: 128 PSYASVIAACKKALNPGGIVIFATINRNLMSFVLAVVCA-EYVLGLLPKGTHDWAS---L 183

Query: 186 RDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLE 230
             P ++     EAG +    TG   ++   R  +  ++     L 
Sbjct: 184 IKPEELKQACSEAGLKQKNITGF-SYNPITRNYYLCKNTMVNYLA 227


>UniRef50_A0L9I8 3-demethylubiquinone-9 3-methyltransferase n=2 Tax=Proteobacteria
           RepID=A0L9I8_MAGSM
          Length = 241

 Score =  171 bits (433), Expect = 2e-41,   Method: Composition-based stats.
 Identities = 43/206 (20%), Positives = 80/206 (38%), Gaps = 9/206 (4%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVL---AEMGPQKLRVLDAGGGEGQTAIKM 62
           F+ +A ++                    +  +L   A+     + +LD G G G  A  M
Sbjct: 13  FERMAHEWWDPAGKFRTLHEINPARVGYIKEILTGSAQGDLAGINLLDIGCGGGILAEAM 72

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
           A+ G  V+  D S ++I  A       G S    +   +A ++A       D++L   VL
Sbjct: 73  ADNGANVVGIDRSEKIIGIATAHQAESGSSA--SYRMQSAAELAEAQPASFDVVLAMEVL 130

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSP 182
           E V D  + L    ++L+PGG L     N         + G  +Y+   +P+   +    
Sbjct: 131 EHVPDMTAFLGDCANLLKPGGTLFFATLNRTPKSWLFAIMGA-EYLLRWLPRGTHQF--- 186

Query: 183 DYPRDPAQVYLWLEEAGWQIMGKTGV 208
           +    P+++   L+  G ++    G+
Sbjct: 187 EKFVKPSELRTALQSNGLEMQAVRGL 212


>UniRef50_Q28VP7 3-demethylubiquinone-9 3-methyltransferase n=37 Tax=Proteobacteria
           RepID=UBIG_JANSC
          Length = 254

 Score =  171 bits (433), Expect = 3e-41,   Method: Composition-based stats.
 Identities = 49/220 (22%), Positives = 88/220 (40%), Gaps = 17/220 (7%)

Query: 6   FDDIAEKFSR---------NIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEG 56
           F+ +A ++            +  T    + Q I  +    + A+     L +LD G G G
Sbjct: 22  FEAMAAEWWDLEGKFKPLHMLNPTRLDYITQQIAAEFGRDLKADAPFAGLHILDIGCGGG 81

Query: 57  QTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLI 116
             A  MA  G  V+  D + + I  A+  A   G+   + + H  A+ +A       D++
Sbjct: 82  LLAEPMARLGADVVGADAAERNIPVAQVHAAQSGLE--IDYRHTTAEAMAD-AGEQFDVV 138

Query: 117 LFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKK 176
           L   V+E V DP   L     +L+PGG++     N +       + G  ++V   +PK  
Sbjct: 139 LNMEVVEHVVDPLGYLTACQRLLKPGGLMVCSTLNRNPKSYLMAIIGA-EHVMRWLPKGT 197

Query: 177 KRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLR 216
                      P +++  + +AG   + + G  VF+  L 
Sbjct: 198 HEW---SKFITPDELFDLIRQAGLDPVDRKGF-VFNPLLW 233


>UniRef50_D1JD67 Putative uncharacterized protein n=1 Tax=uncultured archaeon
           RepID=D1JD67_9ARCH
          Length = 252

 Score =  171 bits (433), Expect = 3e-41,   Method: Composition-based stats.
 Identities = 37/170 (21%), Positives = 72/170 (42%), Gaps = 6/170 (3%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
           ++ +   A+ +S+++  +      +    +    V    G +KL VLD G G    A  +
Sbjct: 6   NKYWSKDADNYSKSVRRSMHSAKEKKGWQEIFTEVF---GKEKLNVLDVGTGPVIIAFLL 62

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
           AE GH V   DLS +M+  A++ A    +   ++F H  A+++    +   D ++   VL
Sbjct: 63  AELGHDVTGVDLSEEMLRNARENAAIFNIP--VEFRHGDAENLP-FEDESFDAVVNRHVL 119

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGM 172
             + +P   +     VL+ GG + ++  N         +      V A +
Sbjct: 120 WTLPNPERAIAEWRRVLKTGGKIVIVDGNWFLNPEFRSLNRRARGVLAML 169


>UniRef50_B8GRY2 Ubiquinone biosynthesis O-methyltransferase n=1
           Tax=Thioalkalivibrio sp. HL-EbGR7 RepID=B8GRY2_THISH
          Length = 251

 Score =  170 bits (431), Expect = 5e-41,   Method: Composition-based stats.
 Identities = 42/210 (20%), Positives = 88/210 (41%), Gaps = 8/210 (3%)

Query: 2   QDRNFDDIAEKFSRNIYGTTK-GQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
            ++ +D     +  +     +   +R  +  +      +    + L+VLD G G G  + 
Sbjct: 25  AEKWWDTTGPFWPLHTLNRLRVAYIRDRLCERLDRDPASARPLEGLKVLDIGCGGGILSE 84

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
            MA  G  V   D++ + I  A   A+ + +   +++   +A+++A       DL+L   
Sbjct: 85  SMARLGADVHGIDVTPRNIAVASLHAQGQDLP--LRYETVSAEELAERG-EQYDLVLNME 141

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
           V+E VAD    +     ++RPGG   +   N + +     + G  +Y+   +P+   +  
Sbjct: 142 VVEHVADLPGFMAACNRLVRPGGYGFIATINRNPVSFLVAILGA-EYLLRWLPRGTHQW- 199

Query: 181 SPDYPRDPAQVYLWLEEAGWQIMGKTGVRV 210
                  P ++   L   G +++ + GVRV
Sbjct: 200 --RRFPKPGELESLLAADGLEVIERIGVRV 227


>UniRef50_Q2FMN6 UbiE/COQ5 methyltransferase n=1 Tax=Methanospirillum hungatei JF-1
           RepID=Q2FMN6_METHJ
          Length = 253

 Score =  170 bits (430), Expect = 5e-41,   Method: Composition-based stats.
 Identities = 45/231 (19%), Positives = 93/231 (40%), Gaps = 17/231 (7%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M    +D+ AE++        + +      W +L +         + VLD G G G+ ++
Sbjct: 11  MIQSAWDESAERYDMQHAHGVQSEEEHTA-WVNLFKQF--TSDTPITVLDIGCGTGEMSL 67

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
            +AE GH V   DLS  M+ RA+  A  KG S  + F    A+ ++ + +   DL++   
Sbjct: 68  LLAEMGHSVHAIDLSENMLKRAEDKARKKGYS--ISFSIDDAESLS-YDDESFDLVINRH 124

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMH-----------NMVAGNFDYVQ 169
           +L  + DP   L+    VL+P G+++++        +             +++   +  +
Sbjct: 125 LLWTLPDPEKALREWNRVLKPRGMIAVIDGLWFPESLSGKSRRFLSKLGILISERRNPFK 184

Query: 170 AGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQ 220
           +  P +    L      +  +   ++E AG+  +    +       R+   
Sbjct: 185 SYYPDELIDNLPHPKGMEAFEAVKYVERAGFHNVTLHSLDEIMTIQRKYMP 235


>UniRef50_Q0F561 3-demethylubiquinone-9 3-methyltransferase n=2 Tax=Proteobacteria
           RepID=Q0F561_9RHOB
          Length = 277

 Score =  169 bits (429), Expect = 7e-41,   Method: Composition-based stats.
 Identities = 50/211 (23%), Positives = 89/211 (42%), Gaps = 15/211 (7%)

Query: 5   NF-DDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
            F   IAE F+               LW+  D        Q L +LD G G G  +  +A
Sbjct: 50  YFTSQIAEHFAL---DLPFEPAPNDNLWRLYD---LGKPLQGLSILDVGCGGGLVSEPLA 103

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
             G +V   D SA  I  A Q A+   ++  + ++H  A+D+ +  +   D+++   V+E
Sbjct: 104 RLGAEVTGIDASAMSIQVATQHAQNT-LTP-VTYVHTLAEDLVAQ-QQQFDVVINAEVVE 160

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPD 183
            V D   ++     +++PGG+L L   N   +     + G  +YV   +P       S  
Sbjct: 161 HVQDQALLINQCAQLVKPGGMLILATLNRTVISYVFAIVGA-EYVMRYLPIGTH---SWS 216

Query: 184 YPRDPAQVYLWLEEAGWQIMGKTGVRVFHDY 214
               P ++  W +  G ++   TG++ F+ +
Sbjct: 217 KFVKPTELSAWAKSGGCELTSHTGMK-FNPW 246


>UniRef50_D1V817 Methyltransferase type 12 n=2 Tax=Frankia RepID=D1V817_9ACTO
          Length = 276

 Score =  169 bits (429), Expect = 8e-41,   Method: Composition-based stats.
 Identities = 68/259 (26%), Positives = 119/259 (45%), Gaps = 17/259 (6%)

Query: 8   DIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGH 67
            +A  + +    T +G +RQ ++ + L   L  +     R+LD GGGEG  A  +A  G+
Sbjct: 21  ALAPGY-QAHTATLRGAVRQRLVTRAL---LTHLPTPPGRILDVGGGEGTQARALARLGY 76

Query: 68  QVILCDLSAQMIDRAKQAA--EAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV 125
           +V +CD   +M+ +A +        V D +  +H    D AS +    D +L H VL ++
Sbjct: 77  EVTICDPDPEMLRQADERLSGADAAVRDRITLVHGDGHDAASLVGGGWDGVLCHGVLMYL 136

Query: 126 ADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLS---- 181
            DP ++L  L  V   GGV+S++  NA  L +   + G +    + + ++ +        
Sbjct: 137 TDPAALLHVLADVTGAGGVISVVGKNATALALRAGLQGRWRDTLSLLDEEPRAAAGTVTE 196

Query: 182 ------PDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRY 235
                 P    DP Q+   L  AG + +   G+RV  D+L +     D  + ++E E R 
Sbjct: 197 IGNLGVPSRGDDPHQIRDLLSAAGTEPLAWYGIRVLTDHLGDTPPGPD-LDTVVEAEWRA 255

Query: 236 CRQEPYITLGRYIHVTARK 254
             ++PY  + R  H+  R+
Sbjct: 256 GERDPYRQVARLYHLIHRR 274


>UniRef50_A7MPA9 3-demethylubiquinone-9 3-methyltransferase n=6
           Tax=Gammaproteobacteria RepID=UBIG_ENTS8
          Length = 243

 Score =  169 bits (428), Expect = 1e-40,   Method: Composition-based stats.
 Identities = 53/251 (21%), Positives = 97/251 (38%), Gaps = 29/251 (11%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGP-QKLRVLDAGGGEGQTAIKMAE 64
           F+ +A ++        + +    I    L  +    G     +VLD G G G  +  MA 
Sbjct: 20  FEAVASRW---WDTEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILSESMAR 76

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
            G  V   D+ A+ +  A+  A   GV  N  ++    ++ A+      D++    +LE 
Sbjct: 77  EGANVTGLDMGAEPLAVARLHALESGVELN--YVQQTVEEHAAQHAGAYDVVTCMEMLEH 134

Query: 125 VADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDY 184
           V DPRSV+Q    +++PGG +     N +       V G  +YV   +PK          
Sbjct: 135 VPDPRSVVQACAQLVKPGGHVFFSTLNRNAKSWLMAVVGA-EYVLRMVPKGTHDA---KK 190

Query: 185 PRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPYITL 244
              P+++  W++E   +     G+   ++ L  +                  +  P + +
Sbjct: 191 FIRPSELLGWVDETPLEERHIIGLH--YNPLTNRF-----------------KLAPGVDV 231

Query: 245 GRYIHVTARKP 255
              +H  A+KP
Sbjct: 232 NYMLHTQAKKP 242


>UniRef50_D2SA73 Methyltransferase type 11 n=1 Tax=Geodermatophilus obscurus DSM
           43160 RepID=D2SA73_9ACTO
          Length = 252

 Score =  169 bits (428), Expect = 1e-40,   Method: Composition-based stats.
 Identities = 70/240 (29%), Positives = 101/240 (42%), Gaps = 14/240 (5%)

Query: 26  RQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQA 85
           R   +W  LD ++A    + L+VLD GGG G  A+ +A  GH V + D SA  +    + 
Sbjct: 17  RAVAVWAALDPLVAA--GRPLQVLDVGGGSGNFAVPLARLGHDVTVVDPSADALATLNRR 74

Query: 86  AEAKGVSDNMQFIHCAAQDVASH------LETPVDLILFHAVLEWVADPRSVLQTLWSVL 139
           AE  GV   ++ +      +          E   DL L H+VLE V DP + L+ L   L
Sbjct: 75  AENAGVGARVRGVQGDGDQLHQVVPAGETGEGSYDLALCHSVLEVVDDPAATLRELARAL 134

Query: 140 RPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGM----PKKKKRTLSPDYPRDPAQVYLWL 195
           RPGG  S+   N  G ++   VAG+     A +    P  ++          P  +   +
Sbjct: 135 RPGGTASVASANRAGAVLARAVAGHPVEALALLEDRDPAPRRARRPARRRFSPDDLITLV 194

Query: 196 EEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPYITLGRYIHVTARKP 255
           E AG Q     GV V  D L          EA+  LE       PY  +   +H+ A +P
Sbjct: 195 EAAGLQPGTWRGVSVVSDLL--DVTSGADPEAVRRLELALAGSSPYRDVAAGLHLLATRP 252


>UniRef50_A0Y980 3-demethylubiquinone-9 3-methyltransferase n=1 Tax=marine gamma
           proteobacterium HTCC2143 RepID=A0Y980_9GAMM
          Length = 241

 Score =  169 bits (428), Expect = 1e-40,   Method: Composition-based stats.
 Identities = 43/207 (20%), Positives = 89/207 (42%), Gaps = 12/207 (5%)

Query: 6   FDDIAEKFSR----NIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIK 61
           F+ +A ++               +R   + + + +    +  + LR+LD G G G  A +
Sbjct: 17  FNRLAVQWWDPQGLMWPLHRLNDMRAPFVTEKIQQHFKTVSLKGLRILDIGCGAGLLAER 76

Query: 62  MAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
           MA++G  V   D++A+ I  A+Q A+ +G+   + +   A + +    +   D++L   V
Sbjct: 77  MAKQGATVTGIDVAAKNIGIARQHAQTQGLV--IDYRCGAVEALKDVGD--FDVVLNMEV 132

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLS 181
           +E V+D    +     +   GG++ L   N         + G  +Y+   +P+      +
Sbjct: 133 IEHVSDLPLFMSRTCDLTGAGGLMFLATINRTWFSWLTTIVGA-EYILGWLPRGTH---T 188

Query: 182 PDYPRDPAQVYLWLEEAGWQIMGKTGV 208
                 P +  L L+  G  ++ +TGV
Sbjct: 189 WQRYVTPEEAVLSLQRGGLSVLSRTGV 215


>UniRef50_B7MFZ8 3-demethylubiquinone-9 3-methyltransferase n=131 Tax=Proteobacteria
           RepID=UBIG_ECO45
          Length = 240

 Score =  168 bits (426), Expect = 2e-40,   Method: Composition-based stats.
 Identities = 45/205 (21%), Positives = 84/205 (40%), Gaps = 10/205 (4%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGP-QKLRVLDAGGGEGQTAIKMAE 64
           F+ +A ++        + +    I    L  +    G     +VLD G G G  A  MA 
Sbjct: 20  FEAVASRWWDL---EGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAR 76

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
            G  V   D+  + +  AK  A   G+   + ++    ++ A+      D++    +LE 
Sbjct: 77  EGATVTGLDMGFEPLQVAKLHALESGI--QVDYVQETVEEHAAKHAGQYDVVTCMEMLEH 134

Query: 125 VADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDY 184
           V DP+SV++    +++PGG +     N +G      V G  +Y+   +PK          
Sbjct: 135 VPDPQSVVRACAQLVKPGGDVFFSTLNRNGKSWLMAVVGA-EYILRMVPKGTHDV---KK 190

Query: 185 PRDPAQVYLWLEEAGWQIMGKTGVR 209
              PA++  W+++   +    TG+ 
Sbjct: 191 FIKPAELLGWVDQTSLKERHMTGLH 215


>UniRef50_D2LFP9 Ubiquinone biosynthesis O-methyltransferase n=1 Tax=Rhodomicrobium
           vannielii ATCC 17100 RepID=D2LFP9_RHOVA
          Length = 252

 Score =  168 bits (425), Expect = 3e-40,   Method: Composition-based stats.
 Identities = 46/214 (21%), Positives = 86/214 (40%), Gaps = 16/214 (7%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQL----RQAILWQDLDRVL-----AEMGPQKLRVLDAGGG 54
           R+F+ +A+++       +        R A +  ++ R            Q L V+D G G
Sbjct: 19  RHFESLAKEWWDERGKFSGLHAFNPARLAFIVAEVKRWRKGQFNEFRPLQGLDVVDIGCG 78

Query: 55  EGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVD 114
            G  +  +A  G  V   D   + +  A+  A   G    + + +  A+D+A       D
Sbjct: 79  GGILSEPLARLGGTVTGIDPVEESVGVARAHAAKLGAP--VTYRNVTAEDLAREG-LTFD 135

Query: 115 LILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPK 174
           +++   V+E VADP+S L+T  S+ +PGG++ L   N         V    + +   +P 
Sbjct: 136 VVVASEVIEHVADPQSFLKTCRSLAKPGGLIVLSTLNRTSKSYGLAVFAA-ERILGLVPP 194

Query: 175 KKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
                        P ++   L +AG+    + G+
Sbjct: 195 GTHDW---KKFIKPDELAGALSDAGFAATRRAGM 225


>UniRef50_Q6MHC4 3-demethylubiquinone-9 3-methyltransferase n=1 Tax=Bdellovibrio
           bacteriovorus RepID=Q6MHC4_BDEBA
          Length = 284

 Score =  167 bits (424), Expect = 3e-40,   Method: Composition-based stats.
 Identities = 44/209 (21%), Positives = 85/209 (40%), Gaps = 10/209 (4%)

Query: 2   QDRNFDDIAEKFSRNIYGT-TKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
            +  +D +A+++           + +  +    +   +      K  +LD G G G  A 
Sbjct: 41  NNEAYDHLADRWYEAQDDPIALLRNQHKVEMPWILESIRRNIGYKAEILDMGCGAGFLAN 100

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
            +A  GH+V   DLS   +  A    E++ ++ ++ +       V        D++    
Sbjct: 101 DLAAAGHKVTGIDLSTSSLKVA----ESRDLTHSVHYRQGDVYQVP-FPNESFDVVAAMD 155

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
           +LE V+DP+ V+     VLRPGG+     +N + L    ++ G   +V+         +L
Sbjct: 156 LLEHVSDPQRVIAEASRVLRPGGLFFFNTFNKNPLAWLVVIKGMEWFVKNTPNDYHVYSL 215

Query: 181 SPDYPRDPAQVYLWLEEAGWQIMGKTGVR 209
                 +P ++ LWLE+         G+R
Sbjct: 216 ----FIEPKKLKLWLEDFSLDTQEIRGIR 240


>UniRef50_Q2FPU4 UbiE/COQ5 methyltransferase n=1 Tax=Methanospirillum hungatei JF-1
           RepID=Q2FPU4_METHJ
          Length = 250

 Score =  167 bits (424), Expect = 3e-40,   Method: Composition-based stats.
 Identities = 45/215 (20%), Positives = 86/215 (40%), Gaps = 22/215 (10%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
            ++  A +++  +    K +   A  W+ L      +G   L++LD G G G  +I +A 
Sbjct: 8   YWNSGAFRYNSGVERFLKSEKGTAG-WKSLFS--EYLGTAPLKILDVGTGPGSISIPLAS 64

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
            GH V   DLS  M+D A++ A A  V   + F    A+++    +   D ++   VL  
Sbjct: 65  MGHMVTAVDLSDNMLDLARKNAVASNVI--VDFRKGDAENLP-FDDNTFDAVVNRWVLWT 121

Query: 125 VADPRSVLQTLWSVLRPGGVLSLMFYNAH-------------GLLMHNMVAGNFDYVQAG 171
           V DP S L+    V++PGG + ++  N +                ++  +    +  +  
Sbjct: 122 VPDPTSALREWTRVVKPGGRVCIIDGNWYSGRKTFVQKVWKQASRLYISIRERRNAWKNI 181

Query: 172 MPKKKKR-TLSPDYPRDPAQVYLWLEEAGWQIMGK 205
            P+  +    +      P    +  + AG   +  
Sbjct: 182 DPEVIQDLWSTHAN--RPEDDMVLFQNAGLSDVQV 214


>UniRef50_C5CH90 Methyltransferase type 11 n=1 Tax=Kosmotoga olearia TBF 19.5.1
           RepID=C5CH90_KOSOT
          Length = 256

 Score =  167 bits (424), Expect = 3e-40,   Method: Composition-based stats.
 Identities = 56/266 (21%), Positives = 115/266 (43%), Gaps = 23/266 (8%)

Query: 1   MQD--RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQT 58
           M +    +DD+A ++          +    +L+ ++ R L        ++LD G G G+ 
Sbjct: 1   MNESWEYYDDVASRYDYM------YEEPYWVLYHEIVRKLINEHQVNGKILDLGTGTGRW 54

Query: 59  AIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILF 118
           AI++A++G ++I  D + +M+  A++ A+  GV  N++F   + + +        D +L 
Sbjct: 55  AIELADKGMEIIAVDPAEKMLKVAEEKAKLYGV--NIKFTKASGEALP-FESNTFDFVLA 111

Query: 119 HA-VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKK 177
              VL +   P  VL+ +  VL+  G L     NA+  L   +  G     +  + +++K
Sbjct: 112 MGDVLSYAKSPEKVLEEIKRVLKNRGKLLATVDNAYAFLHDFISQGETYNARRFIERERK 171

Query: 178 RTLS---------PDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEAL 228
             +             P  P  +   ++ A  Q++    + VF  Y  EK  +    + +
Sbjct: 172 VPIGDSSVSEKHFYTRPYFPEDIEKLVKNASMQLIDIAALVVFAPYSEEKLAR--NLDRI 229

Query: 229 LELETRYCRQEPYITLGRYIHVTARK 254
           ++ E  +CR++       ++   ARK
Sbjct: 230 VQWELEFCRRKELFGRAEHLFFCARK 255


>UniRef50_C4XNC1 Putative 3-demethylubiquinone-9 3-methyltransferase n=1
           Tax=Desulfovibrio magneticus RS-1 RepID=C4XNC1_DESMR
          Length = 264

 Score =  167 bits (423), Expect = 3e-40,   Method: Composition-based stats.
 Identities = 47/246 (19%), Positives = 87/246 (35%), Gaps = 18/246 (7%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
            +DD A  +S   +     +   A  +  + R    +G     +LD G G G  A + A 
Sbjct: 16  WWDDDAGPYSTIRFFINPPR---ANYFARVLRQEGLLGKTGATMLDVGCGGGLLAEEFAR 72

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
            G +V   D + + +  A+  A   G   ++ +     + +   ++   D +    VLE 
Sbjct: 73  MGLRVTGVDPAPESVATARTHAAEAGF--DIVYRVGRGEALP-FVDEAFDAVACCDVLEH 129

Query: 125 VADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKK--KRTLSP 182
           V +P +V+  +  VL+PGG+L     N        ++    D+    +       +    
Sbjct: 130 VDEPAAVIAEMARVLKPGGLLLYDTVNRTLRSWFAVIKLMQDWPSTTVFDAGVPVQAHVW 189

Query: 183 DYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPYI 242
           D    PA+V   L         + G+             R+     L L  R      + 
Sbjct: 190 DKFLKPAEVAAMLRRHDLDPREQRGI----------ATSRNPLACWLGLRQRAKGLLTFQ 239

Query: 243 TLGRYI 248
            LG+ +
Sbjct: 240 ELGKRL 245


>UniRef50_Q482G8 3-demethylubiquinone-9 3-methyltransferase n=27
           Tax=Gammaproteobacteria RepID=UBIG_COLP3
          Length = 246

 Score =  167 bits (423), Expect = 4e-40,   Method: Composition-based stats.
 Identities = 43/212 (20%), Positives = 87/212 (41%), Gaps = 14/212 (6%)

Query: 6   FDDIAEKFSRNIYGTTKGQ----LRQAILWQDLDRVLAEMGPQ----KLRVLDAGGGEGQ 57
           F+ +A ++               LR   + Q +   +  +  +     ++++D G G G 
Sbjct: 16  FEQVASQWWDLTGDFKPLHQINPLRVQFISQHIALQVEGIDSKNGFYDMQIIDVGCGGGI 75

Query: 58  TAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLIL 117
            +  +A+ G  V   D+  + ++ AK  A   GVS  + +    A++ A       D++ 
Sbjct: 76  LSESLAKLGANVTGIDMGTEPLNVAKLHALETGVS--INYQKITAEEKALENPGTFDVVT 133

Query: 118 FHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKK 177
              +LE V DP SV+Q   ++++PGG++     N         +    + +   +P    
Sbjct: 134 CMEMLEHVPDPASVIQACSTLVKPGGLIFFSTLNKSIKSYLLAILAA-EKLLKIVPDGTH 192

Query: 178 RTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVR 209
                D    P+Q+  W EE G + +  +G+ 
Sbjct: 193 D---HDKFIRPSQLIGWAEEHGLKCIDASGIH 221


>UniRef50_Q2NSL7 3-demethylubiquinone-9 3-methyltransferase n=305 Tax=Proteobacteria
           RepID=UBIG_SODGM
          Length = 249

 Score =  166 bits (420), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 45/205 (21%), Positives = 82/205 (40%), Gaps = 10/205 (4%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAE-MGPQKLRVLDAGGGEGQTAIKMAE 64
           FD +A ++        + +    I    LD +L    G     VLD G G G  A  MA 
Sbjct: 28  FDAVAARWWDL---EGEFKPLHHINPLRLDYILERSGGLFGKNVLDVGCGGGILAESMAR 84

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
            G +V   D+ A+ +  A+  A   GV   + +     ++ A       D++    +LE 
Sbjct: 85  EGAKVTGLDMGAEPLAVARLHALESGVM--LAYHQQTVEEHAEAHPGAYDVVTCMEMLEH 142

Query: 125 VADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDY 184
           V DP S+++    +++PGG +     N +       + G  +YV   +P+          
Sbjct: 143 VPDPASIVRACARLVKPGGEVFFSTLNRNPKAWLMAIVGA-EYVLRMVPRGTHD---ITK 198

Query: 185 PRDPAQVYLWLEEAGWQIMGKTGVR 209
              PA++  W+++   +     G+ 
Sbjct: 199 FIKPAELLGWVDDTPLREQHIIGLH 223


>UniRef50_Q8TJ84 UbiE/COQ5 methyltransferase n=1 Tax=Methanosarcina acetivorans
           RepID=Q8TJ84_METAC
          Length = 251

 Score =  165 bits (419), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 56/256 (21%), Positives = 95/256 (37%), Gaps = 21/256 (8%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
            ++  ++ F ++    T  +  +      L   L +      ++LD G G G  ++ +A+
Sbjct: 11  FWNYRSQTFDKSPGHYTASKEEEEAWKGLLRSKLDDAE----KILDIGSGTGFLSLMLAD 66

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
            G++V+  DLS +MI RA   A+ +G+S  + F    A+ +        D I+  AVL  
Sbjct: 67  MGYEVVGIDLSEEMIARASAKAKERGLS--IDFHQDDAEQL-GFENNSFDAIVNRAVLWT 123

Query: 125 VADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDY 184
           +  P   ++    VLRPGG L    +         +       V        +R      
Sbjct: 124 LPHPDIAVREWMRVLRPGGKLCFFLHVPRNEREDAL----QKQVLNLWILLSERRNPWRT 179

Query: 185 PRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPYITL 244
                Q        G +        V  D L+         E + E+ET   R+ PY   
Sbjct: 180 LGSKGQAVNLPYNGGVKP------GVILDLLKSVGYSHVFAEPMHEIETLKSRRMPYPYR 233

Query: 245 GRYIH----VTARKPQ 256
             + H     TA KP+
Sbjct: 234 ISHGHGQFCYTAEKPK 249


>UniRef50_B6YVU2 UbiE/COQ5 methyltransferase n=4 Tax=Thermococcus RepID=B6YVU2_THEON
          Length = 223

 Score =  165 bits (418), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 45/223 (20%), Positives = 81/223 (36%), Gaps = 23/223 (10%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M +  F+ IA ++    Y T  GQ         +  +L     +  + LD G G G   +
Sbjct: 1   MAE-YFNRIAGRYDD-WYRTKTGQYVDRTEKWLVFSMLQ---TKSGKALDLGCGTGNYTL 55

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
           ++  RG  VI  D S  M++ A            +  I   A  +    +   DL+L   
Sbjct: 56  ELKRRGFDVIGLDASEGMLEIAMAK--------GLNCIKGDAYSLP-FPDESFDLVLSVT 106

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
           + E++ +P  V+  +  VL+PGG + +   N             F  +++   +   R  
Sbjct: 107 MFEFIHEPEKVIAEIHRVLKPGGEVLIGTMNGRSPWFF------FKRLKSLFVETAYRY- 159

Query: 181 SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRD 223
                  P ++ L L+  G+  +   GV  F  +         
Sbjct: 160 --ARFYTPRELELLLKNGGFTEVESAGVIFFPSFWPFLDVAER 200


>UniRef50_A3TKD6 Putative methyltransferase n=1 Tax=Janibacter sp. HTCC2649
           RepID=A3TKD6_9MICO
          Length = 258

 Score =  165 bits (418), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 71/241 (29%), Positives = 106/241 (43%), Gaps = 11/241 (4%)

Query: 26  RQAILWQDLDRVLAEMG---PQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRA 82
           R A +W  +D V+        + LRV+D GGG G  A+ +A  GH V + D S   +   
Sbjct: 18  RTAAMWAAVDEVVRARSAELERPLRVIDLGGGTGGLAVPLAVAGHDVTVVDPSPDALASL 77

Query: 83  KQAAEAKGVSDNMQFIHCAAQDVASH-LETPVDLILFHAVLEWVADPRSVLQTLWSVLRP 141
           ++ A     S  +  +   A  + S       DL+L H  LE+V DP++ L  +  VL P
Sbjct: 78  RRRAAEAQASSRVSAVQGDADTLESLVGRDRPDLVLCHGTLEYVDDPQATLAQIAGVLAP 137

Query: 142 GGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPD---YPRDPAQVYLWLEEA 198
           GG+LSL+       ++   +AG F    A + +   R    D      D A V   +E +
Sbjct: 138 GGILSLVVPQRSAAVIARALAGQFVQALAALDRPDGRWGDADPVPRRFDRAGVVGLIEAS 197

Query: 199 GWQIMGKTGVRVFHDYLREKHQQRD-CYEALLELETRYCRQEPY---ITLGRYIHVTARK 254
           G  I G  G+R+F D +       D    ALL+LE        +     LG  +HV A +
Sbjct: 198 GLTITGAHGIRIFSDLVPSALVDSDADRAALLDLERAVAAHPEFAVLADLGTSLHVIASR 257

Query: 255 P 255
           P
Sbjct: 258 P 258


>UniRef50_B8H209 3-demethylubiquinone-9 3-methyltransferase n=13
           Tax=Alphaproteobacteria RepID=UBIG_CAUCN
          Length = 252

 Score =  164 bits (415), Expect = 4e-39,   Method: Composition-based stats.
 Identities = 45/200 (22%), Positives = 77/200 (38%), Gaps = 15/200 (7%)

Query: 6   FDDIAEKFSRNIYGT---------TKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEG 56
           F  IA ++                    +R+  L +      A    + L +LD G G G
Sbjct: 21  FSAIAAEWWDPKGKFAPLHVFNPCRLAFIREQALARFDRDGAARAPFEGLTLLDIGCGGG 80

Query: 57  QTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLI 116
             +  MA  G  V   D S + I  A   A  +G+  ++ +    A+ + +    P D++
Sbjct: 81  LLSEPMARLGFAVTAIDASEKNIKTAATHAAEQGL--DIGYRPATAEQLLAEGAGPFDVV 138

Query: 117 LFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKK 176
           L   V+E VADP   L+T   +L+PGG++ +   N     +     G  +YV   +P   
Sbjct: 139 LTMEVIEHVADPGEFLRTCAKLLKPGGIMFVATLNRTLKALALAKIGA-EYVLRWVPPGT 197

Query: 177 KRTLSPDYPRDPAQVYLWLE 196
                      P ++  +L 
Sbjct: 198 HDW---KQFLKPEELRAFLA 214


>UniRef50_B6BTP2 3-demethylubiquinone-9 3-O-methyltransferase n=1 Tax=beta
           proteobacterium KB13 RepID=B6BTP2_9PROT
          Length = 237

 Score =  163 bits (414), Expect = 4e-39,   Method: Composition-based stats.
 Identities = 50/231 (21%), Positives = 91/231 (39%), Gaps = 11/231 (4%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           F+ IA K+      +++ +    I    ++ +       +  +LD G G G  A  MA+ 
Sbjct: 16  FNKIAHKW---WDPSSEFKPLHDINPLRVNYINDLFPLNEKNILDVGCGGGILAESMAKL 72

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV 125
           G  V   D S   I  AK  A+   +S  + +     +D         D+I    ++E V
Sbjct: 73  GGNVTGIDQSDIAIKIAKLHAKENNLS--IDYKLLNIEDFLKKDSNKFDVITCLEMIEHV 130

Query: 126 ADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYP 185
            DP S++++    L+  G L +   N +       + G  +Y+   +PK        D  
Sbjct: 131 PDPASIIKSCSKKLKKNGRLYVSTINRNLKAFLFAIVGA-EYILNLLPKGTHHY---DKF 186

Query: 186 RDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYC 236
             P++V  W       I   TG+  ++ +L++     D     + LE R+ 
Sbjct: 187 IKPSEVKSWANSLNMNISNITGM-TYNPFLKKYSLGSDVSVNYI-LELRFN 235


>UniRef50_O74421 Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial n=1
           Tax=Schizosaccharomyces pombe RepID=COQ3_SCHPO
          Length = 271

 Score =  163 bits (414), Expect = 4e-39,   Method: Composition-based stats.
 Identities = 51/257 (19%), Positives = 99/257 (38%), Gaps = 27/257 (10%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGP-QKLRVLDAGGGEGQTAIKMA 63
           +F+++A+ +     G+    L  +     +  V  E       ++LD G G G  +  MA
Sbjct: 37  HFNELAKTWWDWDGGSRLLHLMNSTRLDFMTEVFRERNCFSGKKILDIGCGGGILSESMA 96

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKG-VSDNMQFIHCAAQ--DVASHLETPVDLILFHA 120
             G  V   D S   I+ AK+ A     ++  +++IH + +   + +      D++    
Sbjct: 97  RLGASVTAVDASPMAIEVAKKHASLDPVLNGRLEYIHGSVEGSQLPT----TFDVVTCME 152

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
           VLE V  PR  L +L   ++P G L L   +   LL   +     ++V   +P       
Sbjct: 153 VLEHVEQPRDFLFSLMEKVKPNGRLVLSTISRT-LLARLLTITLAEHVLRIVPVGTH--- 208

Query: 181 SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP 240
           + +      ++  +L+E  W I    GV  ++   ++    +                  
Sbjct: 209 TFEKFIRADELSNFLKEQNWIINDIRGV-CYNPLKQQWTLDKPG--------------SS 253

Query: 241 YITLGRYIHVTARKPQS 257
            + L     ++A+KP S
Sbjct: 254 GLGLSCNYFLSAQKPMS 270


>UniRef50_Q6DHK4 Coenzyme Q3 homolog, methyltransferase (Yeast) n=2 Tax=Danio rerio
           RepID=Q6DHK4_DANRE
          Length = 319

 Score =  163 bits (413), Expect = 5e-39,   Method: Composition-based stats.
 Identities = 40/215 (18%), Positives = 75/215 (34%), Gaps = 15/215 (6%)

Query: 4   RNFDDIAEKFSR---------NIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGG 54
           R F  +A K+           ++       +R  +L     R L +     LR+LD G G
Sbjct: 75  RKFQAMASKWWDLQGELSALHSMNDLRVPFIRDNLLNMHGVRQLGK-PLSGLRILDVGCG 133

Query: 55  EGQTAIKMAERGHQVILCDLSAQMIDRAKQAAE-AKGVSDNMQFIHCAAQDVASHLETPV 113
            G  +  +   G  V+  D     +  A+          + +++  C  +++A       
Sbjct: 134 GGLLSEPLGRLGADVLGIDPVEDSVRTAELHCSYDPDFRERVRYQACTLEELAEDEAESF 193

Query: 114 DLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMP 173
             I+   V+E +AD  +       VL+PGG L +   N   L     +    + +   +P
Sbjct: 194 HAIVASEVVEHLADLDAFANCCHQVLKPGGSLFITTINKTNLSYVFGIVAA-EQLLRIVP 252

Query: 174 KKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
                    +    P  +   LE  G+ +    G+
Sbjct: 253 SGTHDW---EKFISPEDLERLLESFGFYVEAIRGM 284


>UniRef50_Q5WW02 3-demethylubiquinone-9 3-methyltransferase n=4 Tax=Legionella
           pneumophila RepID=Q5WW02_LEGPL
          Length = 230

 Score =  163 bits (413), Expect = 6e-39,   Method: Composition-based stats.
 Identities = 43/220 (19%), Positives = 81/220 (36%), Gaps = 13/220 (5%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
             F  +A  +          +    I     + +   +  + LRVLD G G G     MA
Sbjct: 14  HKFAQLANDWWDTNGPL---RTLHDINGTRFEFISEHINLKGLRVLDVGCGGGILCESMA 70

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
           + G  V   D   + I  AK+ A    +   + +     ++   +     D+I    +LE
Sbjct: 71  KAGAYVSGLDAEPEAIQVAKEHAHKNQL--QIDYFCNPIEE---YENQGFDVITCMELLE 125

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPD 183
            V +P  VLQ    +L+P G+L L   +         +    +YV   +P++       D
Sbjct: 126 HVQNPELVLQHCKRLLKPNGLLFLSTISRTLKAYLGAIIAA-EYVLNLLPRQTHDY---D 181

Query: 184 YPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRD 223
               P+++          ++   G+  ++ +LR+     D
Sbjct: 182 KFIKPSELVKMARLYDLNLIDMKGL-CYNPFLRKTTLVSD 220


>UniRef50_D0NUY8 3-demethylubiquinone-9 3-methyltransferase, putative n=1
           Tax=Phytophthora infestans T30-4 RepID=D0NUY8_PHYIN
          Length = 252

 Score =  162 bits (411), Expect = 8e-39,   Method: Composition-based stats.
 Identities = 44/217 (20%), Positives = 82/217 (37%), Gaps = 17/217 (7%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQL------RQAILWQDLDRVLAE------MGPQKLRVLDA 51
           R F+  +  +      T  G L      R   +   +            M  + LRV D 
Sbjct: 11  RKFNAASSDWWTPKSTTGVGPLHQINPVRVKYIRSHVIEHFGHTTDEDPMPLRGLRVADV 70

Query: 52  GGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLET 111
           G G G  +  +   G  ++  D     I  AK+ A     ++ + +  C + D+      
Sbjct: 71  GCGGGILSEALCRIGGTMVSADPGEDNIAAAKKHAAMSRHTNTIDYRQCTSDDLVVQG-E 129

Query: 112 PVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAG 171
             D++    V+E V+D  + L +L  +++PGG+L L   N   L     + G  +YV   
Sbjct: 130 QFDVVCSLEVIEHVSDVSAFLHSLTPLVKPGGLLFLSSINRTALSAALAI-GAAEYVMRI 188

Query: 172 MPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
           +P         +    P ++   L + G+ +   +G+
Sbjct: 189 VPPGTHDW---NKFVRPDEIETELRKNGFTVKDVSGI 222


>UniRef50_C1MP91 Predicted protein n=1 Tax=Micromonas pusilla CCMP1545
           RepID=C1MP91_9CHLO
          Length = 366

 Score =  162 bits (411), Expect = 1e-38,   Method: Composition-based stats.
 Identities = 37/176 (21%), Positives = 66/176 (37%), Gaps = 6/176 (3%)

Query: 35  DRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAE-AKGVSD 93
           D          LRVLD G G G     +A  G  V   D   + ID AK+ A     +  
Sbjct: 160 DAARDARPLAGLRVLDVGCGGGILCESLARMGADVTGIDAGKRNIDIAKKHASLDPAIDA 219

Query: 94  NMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAH 153
            + +    A+++ +      D +L   V+E V +P + +++L  + RPGG + +   N  
Sbjct: 220 KITYHAAPAEELLA-SGASFDAVLSMEVVEHVDNPETFVKSLHGLTRPGGAVVMSTLNRT 278

Query: 154 GLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVR 209
                  +    + +   +P              P ++ +    AG  +    G+R
Sbjct: 279 ARSYALAIVAA-ERIMGWVPPGTHEF---GKFLTPEELTVLFRRAGLTLREAAGMR 330


>UniRef50_B9M2E9 Ubiquinone biosynthesis O-methyltransferase n=1 Tax=Geobacter sp.
           FRC-32 RepID=B9M2E9_GEOSF
          Length = 258

 Score =  162 bits (411), Expect = 1e-38,   Method: Composition-based stats.
 Identities = 41/243 (16%), Positives = 82/243 (33%), Gaps = 19/243 (7%)

Query: 13  FSRNIYGTTKGQLRQAILWQDLDRV----LAEMGPQKLRVLDAGGGEGQTAIKMAERGHQ 68
           F R+ +   +  L       +  R+        G Q    L+ G G G  + ++A  G  
Sbjct: 4   FDRDPWWQPRSALYMLKTALNPVRINYFRERLHGRQGGTALEVGCGGGILSEEIAALGFT 63

Query: 69  VILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADP 128
               D SA  +  A   A+A G+S  + ++    +++    +   D+     VLE V D 
Sbjct: 64  TTGIDPSAAALQVAADHAKAGGLS--IGYLQAVGENLP-FPDNSFDVAFCCDVLEHVQDQ 120

Query: 129 RSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDP 188
              +  +  VL+PGG+      N         +     + +  +   +    + +    P
Sbjct: 121 TRTVAEIARVLKPGGIFCYDTINRTLASWLVAIGVLQKWKRWAVMPPELH--TWNKFIKP 178

Query: 189 AQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPYITLGRYI 248
            ++ + LE++        G++                  L  L  R   +  Y  L   +
Sbjct: 179 EELKMLLEKSHLGWREHRGIK----------PATSPIRTLSYLRRRARGEWNYKDLALRL 228

Query: 249 HVT 251
            + 
Sbjct: 229 QLI 231


>UniRef50_UPI000186D07C hexaprenyldihydroxybenzoate methyltransferase, putative n=1
           Tax=Pediculus humanus corporis RepID=UPI000186D07C
          Length = 281

 Score =  162 bits (410), Expect = 1e-38,   Method: Composition-based stats.
 Identities = 46/220 (20%), Positives = 88/220 (40%), Gaps = 19/220 (8%)

Query: 9   IAEKFSRNIYGTTKGQ---------LRQAILWQDLDRVLAEMGPQKL---RVLDAGGGEG 56
           IA+ +                    +R  +++     V    GP+ L   ++LD G G G
Sbjct: 46  IADGWWNEHGDLKALHSMNKLRIQLVRDGLMYTKKADVENPNGPRPLNGVKILDVGCGGG 105

Query: 57  QTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKG-VSDNMQFIHCAAQDVASHLETPVDL 115
             +  +A  G  V   D   ++ID AK  A     VS  ++++  + +D A+  +   D 
Sbjct: 106 ILSEPLARIGADVTGIDPGQKLIDIAKTHAAEDPTVSGKIRYLCESIEDHANGHKEKYDA 165

Query: 116 ILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKK 175
           ++   V+E VA     L++  +VL+PGG + +   N         V    +Y+   +PK+
Sbjct: 166 VVASEVIEHVASKEIFLESCANVLKPGGSIFITTINRTTQAWIAGVITA-EYLLHLVPKE 224

Query: 176 KKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYL 215
                  +    P ++    E+         G+  F+++L
Sbjct: 225 THDW---EKFITPHELQFMCEKYDCFTKLVHGM--FYNFL 259


>UniRef50_A4BJS3 Putative SmtA protein n=1 Tax=Reinekea blandensis MED297
           RepID=A4BJS3_9GAMM
          Length = 229

 Score =  161 bits (409), Expect = 1e-38,   Method: Composition-based stats.
 Identities = 74/228 (32%), Positives = 109/228 (47%), Gaps = 2/228 (0%)

Query: 28  AILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGH-QVILCDLSAQMIDRAKQAA 86
            ++     +VL     +  +VLDAGGG GQ +    E+G   V   D+S QM+  A ++ 
Sbjct: 2   RLVDALYRKVLPLDQLENWKVLDAGGGLGQMSHWFLEQGVTSVDYLDVSEQMVTAATESL 61

Query: 87  EAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLS 146
           +    +  +     +  D++       D +  HAVLEW+  P +V+  L   +RPGG L 
Sbjct: 62  QEYYEAGQLNASVGSVTDLSEWPSD-YDFVNVHAVLEWLEKPETVVPILCDRVRPGGYLG 120

Query: 147 LMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKT 206
           LM YN H L+M +M+ G      +G     KR L+P  P DP  V   L+  G  I+ + 
Sbjct: 121 LMVYNRHMLMMRHMMRGTLKRAMSGNMAGDKRGLTPISPMDPQAVAKDLQACGMTILCQA 180

Query: 207 GVRVFHDYLREKHQQRDCYEALLELETRYCRQEPYITLGRYIHVTARK 254
           G+R F D   +   +    EA+ + E   C Q PY  LGRY    ARK
Sbjct: 181 GIRSFSDLTEKAVLEWYTEEAVFDAEQALCEQRPYCDLGRYTLFIARK 228


>UniRef50_D1JD52 Putative uncharacterized protein n=1 Tax=uncultured archaeon
           RepID=D1JD52_9ARCH
          Length = 260

 Score =  161 bits (409), Expect = 1e-38,   Method: Composition-based stats.
 Identities = 53/267 (19%), Positives = 107/267 (40%), Gaps = 33/267 (12%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
             ++ + + F +     T+    Q   W+     L ++G + L++LD G G G  +I +A
Sbjct: 10  NYWNSMGKYFDKRPGDRTE---EQRNAWKQFF--LEKLGKKPLKILDVGTGTGFLSISLA 64

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
           E GH+V+  D+S  M+ +A++ AE +G+  N       A+ ++   +   D+++ +AVL 
Sbjct: 65  EIGHEVMGIDISEGMLSQARKKAEKRGL--NFDLRIEDAESLS-LEDETFDIVVSNAVLW 121

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHG---------------LLMHNMVAGNFDYV 168
            + +P   ++    VL+PGG       +  G               ++        +  +
Sbjct: 122 SLPNPEKAVREWKRVLKPGGTACAFASDMAGQRGIYRQIKRALGDFMVWAIDEKNYWGGL 181

Query: 169 QAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEAL 228
              + KK     S       + +    E  G+  +  T ++       E+ ++R      
Sbjct: 182 DKSVQKKLPLHWSNQSYSRISSIVKLYERCGFDDISITEMKEVSRIRAEERKKRP----- 236

Query: 229 LELETRYCRQEPYITLGRYIHVTARKP 255
             L  R  R+  Y     Y  ++  KP
Sbjct: 237 --LRYRIGRKSSY---TSYCCLSGFKP 258


>UniRef50_B7FTF3 Predicted protein (Fragment) n=1 Tax=Phaeodactylum tricornutum CCAP
           1055/1 RepID=B7FTF3_PHATR
          Length = 249

 Score =  161 bits (409), Expect = 1e-38,   Method: Composition-based stats.
 Identities = 45/226 (19%), Positives = 88/226 (38%), Gaps = 19/226 (8%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEM-------GPQKLRVLDAGG 53
           M +  +D      +R         +R   +   L R   ++         +   VLD G 
Sbjct: 13  MDETWWD------ARKNPLLPMNAVRIRYIGDQLARNQQQLQTTHLVSALEGKTVLDIGC 66

Query: 54  GEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFI-HCAAQDVASHLETP 112
           G G  +  +A  G  V   D S +++D A+   +    + N+ ++ +  A+D++   +  
Sbjct: 67  GGGLLSESLARLGATVTAIDPSQRLVDAARLHGQLDRRTRNINYLGNTTAEDLSQTGDK- 125

Query: 113 VDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGM 172
            D++    V+E   DP S+++   S+++PGG L L   N         + G  +Y+   +
Sbjct: 126 FDVVCLLEVIEHATDPDSLVEAAASMVKPGGYLFLSTLNKTIKSYLLTIVGA-EYIMGYI 184

Query: 173 PKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREK 218
           P              PAQV       G + +  +G+ +    +  K
Sbjct: 185 PPGTHDW---KQYLSPAQVGEMTSRNGLRPVDVSGLVLHQPPMFGK 227


>UniRef50_C7QBJ1 Methyltransferase type 12 n=15 Tax=Actinomycetales
           RepID=C7QBJ1_CATAD
          Length = 263

 Score =  161 bits (408), Expect = 2e-38,   Method: Composition-based stats.
 Identities = 74/236 (31%), Positives = 108/236 (45%), Gaps = 9/236 (3%)

Query: 29  ILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEA 88
           +LWQ L  VL   GP+   VLD GGG G  A+ +AE GH+V + D S   +   ++ A  
Sbjct: 30  VLWQALRTVLDASGPRD--VLDVGGGTGGFAVPIAELGHRVTVVDPSPDALAALERRAAE 87

Query: 89  KGVS-DNMQFIHCAAQDVASH-LETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLS 146
            GV  + ++ +      +  H     VDL+L H VLE   DP + L T+  VLRPGGV+S
Sbjct: 88  SGVPKEALRAVQGDLAGLLEHVEPGSVDLVLCHGVLEMADDPAAGLATVADVLRPGGVVS 147

Query: 147 LMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPD---YPRDPAQVYLWLEEAGWQIM 203
           L+  N    ++   + G+F   +  +     R  + D      D  Q+   L EA   + 
Sbjct: 148 LLAANRTAAVVARALGGHFAEARRALADPTGRFGAQDPLAARFDEEQLSRLLREARLTVQ 207

Query: 204 GKTGVRVFHDYLREKHQQRDCYEA--LLELETRYCRQEPYITLGRYIHVTARKPQS 257
              GVRVF D +       D   A  L  LE     +  +  +   +H+ ARK  S
Sbjct: 208 SVHGVRVFTDLVPGALVDADPQAASDLAALEAAVADRPEFRAVAGRLHLLARKIAS 263


>UniRef50_Q3SVP3 3-demethylubiquinone-9 3-methyltransferase n=45
           Tax=Alphaproteobacteria RepID=UBIG_NITWN
          Length = 261

 Score =  161 bits (408), Expect = 2e-38,   Method: Composition-based stats.
 Identities = 49/212 (23%), Positives = 80/212 (37%), Gaps = 9/212 (4%)

Query: 25  LRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQ 84
           +R A   +      +      LR+LD G G G         G QVI  D SA  I  AK 
Sbjct: 59  IRDAACRKFDRNARSLNCLAGLRLLDIGCGAGLLCEPFTRLGAQVIGVDPSASNIAAAKL 118

Query: 85  AAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGV 144
            AE   +S  + +     +D+        D+IL   V+E VAD    L    ++L+PGG+
Sbjct: 119 HAEKAHLS--IDYRCTTVEDMDVR--ERFDIILAMEVVEHVADVGLFLDRCAAMLKPGGM 174

Query: 145 LSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMG 204
           ++    N +       +    +YV   +P+   +    D    P ++    E  G  I  
Sbjct: 175 MAASTLNRNWKSFALGIVAA-EYVLRWLPRGTHQW---DKFVTPDELARHFERNGLGITE 230

Query: 205 KTGVRVFHDYLREKHQQRDCYEALLELETRYC 236
           ++GV V+  +        D     + +     
Sbjct: 231 QSGV-VYSPFGDRWSLSSDMDVNYMVVAEAVG 261


>UniRef50_C8WEG5 Ubiquinone biosynthesis O-methyltransferase n=3 Tax=Zymomonas
           mobilis RepID=C8WEG5_ZYMMN
          Length = 263

 Score =  161 bits (407), Expect = 3e-38,   Method: Composition-based stats.
 Identities = 49/213 (23%), Positives = 80/213 (37%), Gaps = 19/213 (8%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLA-----EMGPQKLRVLDAGGGE 55
           M    ++     F  +        +R + + Q +D+                VLD G G 
Sbjct: 39  MAKDWWNP----FGSSAMLHRMNPVRLSYIRQAIDQYFVSAFGNPFPLMGKSVLDIGCGA 94

Query: 56  GQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDL 115
           G  +  +   G  V   D + + I  AK  AE + +  N++++    + V    +T  DL
Sbjct: 95  GLLSEPLCRLGGDVTGVDAAFENIAVAKAHAEEQHL--NIRYLTGELESV---EDTNFDL 149

Query: 116 ILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKK 175
           I    VLE VA+P   +Q +   L P G+L L   N    L+  M+         G+P K
Sbjct: 150 ITAMEVLEHVAEPEQFIQAIADKLDPNGLLILSTPNRT--LLSKMMIIGIGETLGGIPAK 207

Query: 176 KKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
                       P +    LE+AG  +    G+
Sbjct: 208 THDW---SRFLKPEETQKLLEKAGLVVTDIIGM 237


>UniRef50_C3YXC3 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
           RepID=C3YXC3_BRAFL
          Length = 317

 Score =  161 bits (407), Expect = 3e-38,   Method: Composition-based stats.
 Identities = 41/225 (18%), Positives = 82/225 (36%), Gaps = 16/225 (7%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEM--------GPQKLRVLDAGGGE 55
           + F+ +A K+               +    +   L +           + LR+LD G G 
Sbjct: 78  KKFNALASKWWDTKGELKGLHSMNRLRVPMIRDTLVKHHSISKKSRPLEGLRILDVGCGG 137

Query: 56  GQTAIKMAERGHQVILCDLSAQMIDRAKQA-AEAKGVSDNMQFIHCAAQDV-ASHLETPV 113
           G  ++ +A+ G QV   D S + +  A    A    + D + F H   +D+ AS +    
Sbjct: 138 GILSVPLAKLGAQVTGLDASEEAVKAATAHMARDPSLKDTLTFTHGTVEDLVASEVRDYY 197

Query: 114 DLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMP 173
           D ++   V+E V      + +   +++PGG L     N      +  V    +Y+   +P
Sbjct: 198 DALVASEVIEHVDALDDFVGSSCDLVKPGGSLFFTTINRTTQSYYLAVIAA-EYIVGVVP 256

Query: 174 KKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREK 218
           +        +    P ++   L+          G+  F++    +
Sbjct: 257 RGTHNW---NKFVKPEELKDELKANNCHPRLIHGM--FYNPFLNR 296


>UniRef50_A8PNX2 3-demethylubiquinone-9 3-O-methyltransferase n=1 Tax=Rickettsiella
           grylli RepID=A8PNX2_9COXI
          Length = 234

 Score =  161 bits (407), Expect = 3e-38,   Method: Composition-based stats.
 Identities = 42/233 (18%), Positives = 87/233 (37%), Gaps = 10/233 (4%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
             F  +A+++           +   +    L+ +      +  +V+D G G G  A  MA
Sbjct: 12  NKFTALADQWWDVDGPCKPLHIINPL---RLEFLETWQTLKGKKVIDVGCGGGIFAEAMA 68

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
           +RG +V   D S  +ID AK+ A    +   + +    A+  A+H     D++    +LE
Sbjct: 69  QRGAEVTGIDKSGALIDVAKKHAADNQLP--IDYFSAEAESFATHQRESYDVVCCMELLE 126

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPD 183
            V  P S++Q    + +P   +     N +       + G  +++   +P+         
Sbjct: 127 HVPCPLSLIQACSQLAKPNARIFFSTINRNPRAYFLAILGA-EHLLKILPRGTHDY---K 182

Query: 184 YPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYC 236
               P+++ L   +A   +    G+  ++  L+      D     L    +  
Sbjct: 183 KFIRPSELALAGRKAYLTLQKLQGIH-YNPILQHYALSDDIRINYLAAFRKRA 234


>UniRef50_A3TLQ5 S-adenosylmethionine-dependent methyltransferase n=1 Tax=Janibacter
           sp. HTCC2649 RepID=A3TLQ5_9MICO
          Length = 259

 Score =  161 bits (407), Expect = 3e-38,   Method: Composition-based stats.
 Identities = 68/257 (26%), Positives = 123/257 (47%), Gaps = 12/257 (4%)

Query: 7   DDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERG 66
           D+  E +      +  G+LR A++   +D  +AE G + LR+LD GG +G   +  A RG
Sbjct: 5   DERNEAWEA-WKASPWGRLRFALIGDAIDEAIAEFGDRTLRILDVGGADGFETLPYAIRG 63

Query: 67  HQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVA 126
           HQ+ + D +    DR ++AAE  GVSD ++++    +++    +T  D+++ H VL +  
Sbjct: 64  HQLTVADPAEGFFDRGREAAEQLGVSDRVRWVSAGLEELPMAGDTAYDVVVCHFVLHYRP 123

Query: 127 --DPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDY 184
                + + TL  +  P GV+S+   N  GL++  +        +A + +  +   S  +
Sbjct: 124 AGSLGADVATLSRLTAPDGVISIACPNEAGLVLRTLTREGPAAARAELDETTQ--FSHTF 181

Query: 185 PRD-----PAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDC--YEALLELETRYCR 237
             D       +V   L E G       GVR+ +D +     + D   ++ LL LE   CR
Sbjct: 182 GHDSQKVGREEVAAALHENGLVETEWMGVRIANDLIVHDEMKHDPVYFQQLLALERDLCR 241

Query: 238 QEPYITLGRYIHVTARK 254
           ++PY  +     +TA++
Sbjct: 242 RDPYRGIAALWQLTAKR 258


>UniRef50_UPI0000E495F1 PREDICTED: hypothetical protein n=2 Tax=Strongylocentrotus
           purpuratus RepID=UPI0000E495F1
          Length = 351

 Score =  161 bits (407), Expect = 3e-38,   Method: Composition-based stats.
 Identities = 34/168 (20%), Positives = 65/168 (38%), Gaps = 5/168 (2%)

Query: 42  GPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKG-VSDNMQFIHC 100
                 ++D G G G  A  +A  G  VI  D + + I+ A+        +  N+++I  
Sbjct: 152 PLHGATIVDVGCGGGILAEPLARLGATVIGVDATPENIEVAQHHVSHDPTIRGNVKYICG 211

Query: 101 AAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNM 160
            A+D+    +   D ++   VLE V+   + ++T   +++PGG +     N   L     
Sbjct: 212 TAEDLVCTEDEAFDALVCSEVLEHVSHKENFIKTCAELVKPGGSIFFTSVNQTWLSYALG 271

Query: 161 VAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
           +    + V   +P         +    P  +   LEE    +    G+
Sbjct: 272 IVMA-EKVLGLVPDGTHDW---NKFISPGYIQRVLEENDCSVRLTHGM 315


>UniRef50_A5EVK0 Ubiquinone biosynthesis O-methyltransferase n=2
           Tax=Cardiobacteriaceae RepID=A5EVK0_DICNV
          Length = 231

 Score =  161 bits (407), Expect = 3e-38,   Method: Composition-based stats.
 Identities = 46/218 (21%), Positives = 87/218 (39%), Gaps = 11/218 (5%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           FD     F          +    I    +D +   +   +  +LD G G G  +  +A  
Sbjct: 12  FDQYGAHFWDENGA---YRTLHHINPVRVDFIKQFIKLNQKTILDIGCGGGLLSEALARE 68

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV 125
           G QV   DLS+ MI  A+     + ++  + +   ++ D  +      D I+   +LE V
Sbjct: 69  GAQVFGIDLSSSMIAAAEHHLSGQNLA--INYRQISSHDCCAQ-NEQYDHIVCMEMLEHV 125

Query: 126 ADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYP 185
           A+P ++L+ ++++LRP G   L   N +      M+    +Y+   +P+           
Sbjct: 126 ANPAAILRDIYALLRPNGFAFLSTVNRNKRAFFKMIVLA-EYLTKLVPRGTHHYAD---F 181

Query: 186 RDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRD 223
             P ++    E AG   +  +G+  +H   +  H  R 
Sbjct: 182 IRPHELVTMAERAGLSAVALSGM-TYHPLRKSAHLSRH 218


>UniRef50_Q5VMJ1 Putative dihydroxypolyprenylbenzoate methyltransferase n=2
           Tax=Magnoliophyta RepID=Q5VMJ1_ORYSJ
          Length = 221

 Score =  160 bits (406), Expect = 3e-38,   Method: Composition-based stats.
 Identities = 39/220 (17%), Positives = 78/220 (35%), Gaps = 6/220 (2%)

Query: 20  TTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMI 79
           T    +R  +         +    + L+V+D G G G  +  +A  G  V   D   + I
Sbjct: 4   TRLSFIRSTLCRHFRRDPNSSKPLEGLKVIDVGCGGGILSEPLARMGATVTGIDAVDKNI 63

Query: 80  DRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVL 139
             A+  A +   + ++++    A+D+        D ++   V+E VA+P    ++L ++ 
Sbjct: 64  KIARVHAASDPSTASIEYFCTTAEDLVKE-NKQFDAVISLEVIEHVANPSGFCESLSALT 122

Query: 140 RPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAG 199
            P G   +   N         +    +Y+   +PK   +         P ++ L LE A 
Sbjct: 123 VPNGATVISTINRSMRAYATAIVAA-EYILNWLPKGTHQW---SKLVTPEELVLILERAS 178

Query: 200 WQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQE 239
             +    G  V++    E     D     +    +     
Sbjct: 179 ISVQEMAGF-VYNPLRGEWSLSDDLTVNYIAYGMKKVETP 217


>UniRef50_Q48938 Orf3 protein n=3 Tax=Methanosarcina RepID=Q48938_METBA
          Length = 262

 Score =  160 bits (406), Expect = 4e-38,   Method: Composition-based stats.
 Identities = 45/233 (19%), Positives = 91/233 (39%), Gaps = 19/233 (8%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M    +D  +E F  +     + Q  +    +   +V      + L++LD G G G+ ++
Sbjct: 18  MVAHKWDLASETFDTHAGHGIQTQKERDAWKRAFLKVF---PGKSLKILDVGCGTGELSL 74

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
             AE GH+V   D+S QM+  AK  AEA G   ++ F    A++      +  D++    
Sbjct: 75  LFAEMGHEVAGIDISGQMLKIAKAKAEALG--ADITFREGDAEN-PPFDTSSYDIVFSRH 131

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGM-----PKK 175
           +L  + +P+  ++    +LR  G + ++        + +    N   +   +     P+K
Sbjct: 132 LLWTLPNPKVAVENWNRILRKNGKVVIVDGVWDSGTLGSRARKNAGALLTLLLERKDPRK 191

Query: 176 KKRT--------LSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQ 220
                       L         +V  +L  +G+  +    ++   D  +EK  
Sbjct: 192 GHSDYSDELKAQLPHFGGAPLEKVNEYLSNSGFGNIQIFDLKEVRDAQKEKMP 244


>UniRef50_A4FIW0 Methyltransferase n=3 Tax=Actinomycetales RepID=A4FIW0_SACEN
          Length = 272

 Score =  160 bits (406), Expect = 4e-38,   Method: Composition-based stats.
 Identities = 61/264 (23%), Positives = 114/264 (43%), Gaps = 13/264 (4%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M D  +  +A++F+   Y + KG++R  +L Q L   L  + P    VLD GGG G  + 
Sbjct: 1   MDDDTWAGLADQFADGAYASVKGRVRTYVLHQQL---LEHLPPPPAPVLDVGGGAGHQSF 57

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKG--VSDNMQFIHCAAQDVASHLET-PVDLIL 117
            +A+ G+ V L D S+ M+D+A+Q  +         +  +    ++    +       +L
Sbjct: 58  PLAQAGYDVTLLDPSSAMLDKARQRLDRLPDEAQRRVTLLEADGENADEAVNGRRFAAVL 117

Query: 118 FHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKK 177
            H VL +   P  ++  L      GG++S+M  NA+ + +   +   +D   A    + +
Sbjct: 118 CHGVLGYQEQPEPLVDQLCRCAAAGGIVSIMAGNANAMAVRPALERRWDDALASFDARGE 177

Query: 178 RTL--SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEA-----LLE 230
             +   P       ++   +   G + +   GV +F D+L     + D  ++        
Sbjct: 178 IGVLGVPTRADTVEELSELVRSRGVEPLRWYGVWLFVDWLDFSGAELDPGDSEQVAAAAA 237

Query: 231 LETRYCRQEPYITLGRYIHVTARK 254
           +E    R++PY  L R  H+  RK
Sbjct: 238 VELEAGRRDPYRGLSRVFHLVGRK 261


>UniRef50_D1JD78 Putative uncharacterized protein n=1 Tax=uncultured archaeon
           RepID=D1JD78_9ARCH
          Length = 256

 Score =  160 bits (406), Expect = 4e-38,   Method: Composition-based stats.
 Identities = 46/228 (20%), Positives = 88/228 (38%), Gaps = 18/228 (7%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
            R++D  +  + +       G   + I W D+  + + +G ++  VLD G G G  AI +
Sbjct: 16  KRHWDGRSNDYGKF---RGYGSEEEKIAWMDV--LSSALGTERRNVLDVGTGPGDIAIYL 70

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
           AE  H V   D S +M+ RAK   +   +   ++F  C A+D+    +   D ++   +L
Sbjct: 71  AEMEHDVTGIDFSDEMLKRAKGRVKNSNL--QVKFDICDAEDL-YFEDESFDAVICRHLL 127

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFD------YVQAGMPKKK 176
             + +P   L+    V++PGG + ++          + +           Y Q   PK  
Sbjct: 128 WTLPNPGKALREWTRVVKPGGKIVVIDGKWRSSSPIDRMRRLIRSLVFLVYEQRKPPKSY 187

Query: 177 KRT----LSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQ 220
           K+     L      +P +V     +     +    +    +  R    
Sbjct: 188 KKEINGKLPFRNGAEPEKVVELFNDLELVNVSAQDITTVREAQRRNMP 235


>UniRef50_O49354 Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial n=11
           Tax=Embryophyta RepID=COQ3_ARATH
          Length = 322

 Score =  160 bits (405), Expect = 5e-38,   Method: Composition-based stats.
 Identities = 42/235 (17%), Positives = 86/235 (36%), Gaps = 15/235 (6%)

Query: 6   FDDIAEKFSRN---------IYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEG 56
           F  IA+ +  +         +  T    +R  +         +    + L+ +D G G G
Sbjct: 84  FSAIADTWWHSEGPFKPLHQMNPTRLAFIRSTLCRHFSKDPSSAKPFEGLKFIDIGCGGG 143

Query: 57  QTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLI 116
             +  +A  G  V   D   + +  A+  A+   V+  ++++   A+ +A       D +
Sbjct: 144 LLSEPLARMGATVTGVDAVDKNVKIARLHADMDPVTSTIEYLCTTAEKLADEG-RKFDAV 202

Query: 117 LFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKK 176
           L   V+E VA+P    ++L ++  P G   L   N       + + G  +Y+   +PK  
Sbjct: 203 LSLEVIEHVANPAEFCKSLSALTIPNGATVLSTINRTMRAYASTIVGA-EYILRWLPKGT 261

Query: 177 KRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLEL 231
            +  S      P ++ + L+ A   +    G  V++          D     +  
Sbjct: 262 HQWSS---FVTPEEMSMILQRASVDVKEIAGF-VYNPITGRWLLSDDISVNYIAY 312


>UniRef50_A2SPT6 Methyltransferase type 11 n=2 Tax=Methanomicrobiales
           RepID=A2SPT6_METLZ
          Length = 257

 Score =  160 bits (405), Expect = 5e-38,   Method: Composition-based stats.
 Identities = 42/266 (15%), Positives = 88/266 (33%), Gaps = 33/266 (12%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
             ++  +  +  ++    K    + +  +     +      +L+VLD G G G   +  A
Sbjct: 12  NAWNQESNFYDSHVSHGMKSDEEKKLWMEAFSTRVK--NDTQLQVLDVGCGTGAMGLIFA 69

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
           E GH V   DLS  M+D  ++ A    ++ N  F    A+      +   D+++   +L 
Sbjct: 70  EMGHTVEGIDLSEGMMDVGRKKAADMHLAMN--FSSGDAEH-PPFDDGKFDVVVNRHLLW 126

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKR----- 178
            + +P   + + + VL+P G L ++          N V     +  A + +         
Sbjct: 127 TLPNPDKAISSWFRVLKPNGTLLVIDGVWDDGSRLNTVKKKISHKIASLVEAHPHGGKSR 186

Query: 179 -------TLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLEL 231
                   L         +   + E AG+  +    +    D                  
Sbjct: 187 YSEEVSSYLPNKGGTSEEKAKEYFENAGFTNITVVNLDAITD----------EQRKYFSW 236

Query: 232 ETRYCRQEPYITLGRYIHVTARKPQS 257
             +   +        Y  ++ +KP+S
Sbjct: 237 YMKIAPK------STYYLISGKKPES 256


>UniRef50_C6PRH7 Methyltransferase type 11 n=1 Tax=Clostridium carboxidivorans P7
           RepID=C6PRH7_9CLOT
          Length = 252

 Score =  160 bits (404), Expect = 6e-38,   Method: Composition-based stats.
 Identities = 33/169 (19%), Positives = 71/169 (42%), Gaps = 6/169 (3%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           ++  A+ + +      K +  +      L  V+   G +  ++LD G G G  A+ +AE 
Sbjct: 12  WNIWAKGYDKQYSHGLKSEEEKVQWKVFLSEVI---GKESKKILDVGTGTGFLALLLAEL 68

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV 125
           GH     D+S  M++ A++ A+   +  N+ F    A+++    +   D+++   +L  +
Sbjct: 69  GHNCTGLDISEGMMEVARKKAKEAKL--NINFGMGDAENLPCK-DNTYDIVVNRHLLWTI 125

Query: 126 ADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPK 174
             P   L     VL+PGG L ++  +         +      +   + +
Sbjct: 126 PHPEKALSEWIRVLKPGGKLVIIDGDWFYKNSSYEIQKFLGKILIALTE 174


>UniRef50_D2RYJ5 Methyltransferase type 11 n=3 Tax=Haloterrigena turkmenica DSM 5511
           RepID=D2RYJ5_9EURY
          Length = 226

 Score =  160 bits (404), Expect = 6e-38,   Method: Composition-based stats.
 Identities = 44/203 (21%), Positives = 85/203 (41%), Gaps = 16/203 (7%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
           + +DD +E +  +         ++   W  + R     G    R LD G G G  ++ +A
Sbjct: 15  QYWDDRSESYDGDSQHAIHSDEQRDA-WLSILRDWTGDGDPPRRTLDVGCGTGVISLLLA 73

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
           E GH V   DLS  M++RA+  A  +  S  ++F +  A+ +++  E   DL+    ++ 
Sbjct: 74  ELGHVVTGVDLSTDMLERARAKARDRDRS--VEFRNGDAESISA-PENAYDLVTARHLVW 130

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPD 183
            + +P + ++    V+RPGG + L+  +       +              ++    L   
Sbjct: 131 TLPNPLAAIREWQRVVRPGGRIVLIEGHWDFDEAFDG------------YQEIHDELPLY 178

Query: 184 YPRDPAQVYLWLEEAGWQIMGKT 206
             R P ++   LEE G + +   
Sbjct: 179 DGRPPEELVDVLEEHGLERVEYE 201


>UniRef50_Q65VD6 SmtA protein n=2 Tax=Gammaproteobacteria RepID=Q65VD6_MANSM
          Length = 256

 Score =  159 bits (403), Expect = 7e-38,   Method: Composition-based stats.
 Identities = 47/168 (27%), Positives = 76/168 (45%), Gaps = 8/168 (4%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGP-QKLRVLDAGGGEGQTAIKM 62
           R +++ AE +SR+     +   R    WQ L  +LA     Q L+VLD G G G  AI M
Sbjct: 16  RYWNNRAEGYSRHNQQELQSIKRLK--WQQL--LLAHAPKKQNLKVLDIGTGPGFFAIIM 71

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
           A+ G QV   D ++ M+++AK  A    V  +++F+      +    +   DLI+   V 
Sbjct: 72  AQAGAQVTAIDATSNMLEQAKYNAAQAMV--DIRFVRGDVHHLP-FADESFDLIISRNVT 128

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQA 170
             +++P    +    VL+ GG L     N +  L        F+  +A
Sbjct: 129 WNLSEPEQAYKEWHRVLKCGGNLLNFDANWYLFLYDEQRRRAFEQDRA 176


>UniRef50_Q8RJX7 Methyl transferase n=1 Tax=Stigmatella aurantiaca
           RepID=Q8RJX7_STIAU
          Length = 256

 Score =  159 bits (403), Expect = 8e-38,   Method: Composition-based stats.
 Identities = 39/208 (18%), Positives = 76/208 (36%), Gaps = 16/208 (7%)

Query: 13  FSRNIYGTTKGQLR---------QAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
           +    +      +          +   + +L      + P K+RVLD G G G  A + +
Sbjct: 8   YDEMNWWNDDSSVSLLSTSINPCRIAYFHNLLTNRIGLDPTKVRVLDVGCGGGLLAEEFS 67

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
           ++G +V   D SA  I+ AK  +   G+  N+ +    AQ +    +   D++    VLE
Sbjct: 68  KKGWKVTGVDQSAPSIELAKAHSAKVGL--NIDYHVSKAQKLP-FEDETFDIVYCCDVLE 124

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDY-VQAGMPKKKKRTLSP 182
            +    + +     VL+ GGV      N   +     +    ++     +P         
Sbjct: 125 HIPTYPAAVAESARVLKKGGVYLYETINRTFMSKMIAIKMLQEWSWTRVIPDDVHDW--- 181

Query: 183 DYPRDPAQVYLWLEEAGWQIMGKTGVRV 210
                P +++  +  A  Q +   G+ V
Sbjct: 182 KMFIRPEELHNAMHAAKIQNVETAGMTV 209


>UniRef50_B6K7D4 Hexaprenyldihydroxybenzoate methyltransferase n=1
           Tax=Schizosaccharomyces japonicus yFS275
           RepID=B6K7D4_SCHJY
          Length = 268

 Score =  159 bits (402), Expect = 9e-38,   Method: Composition-based stats.
 Identities = 40/213 (18%), Positives = 87/213 (40%), Gaps = 8/213 (3%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMG-PQKLRVLDAGGGEGQTAIKMA 63
           +FDD+A+ +      +    L        +  ++ +       R+LD G G G  +  +A
Sbjct: 34  HFDDLAKTWWDWDGSSRLLHLMNPPRIDFIRSIVKQKNWFPGKRILDVGCGAGILSESLA 93

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKG-VSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
             G  V+  D S   I+ A+Q  +    + + +++   + ++  +      D +    V+
Sbjct: 94  RLGAHVVGLDASPGTIEAAQQHMKQDPSLQNKLRYKLGSIEN-TNFNGKQFDAVTVMEVV 152

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSP 182
           E VA+P + L  L   ++P G + L   +   ++   +     + V   +P       + 
Sbjct: 153 EHVAEPANFLNELMRHVKPLGYVFLSTISRT-MVSRLLTLTLAENVLHIVPPGTH---TY 208

Query: 183 DYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYL 215
           +    P ++  +  E GW + G+  V  F+ +L
Sbjct: 209 EKYIRPEEMREFFLEKGWAVNGERSV-AFNPFL 240


>UniRef50_Q5PAV2 3-demethylubiquinone-9 3-methyltransferase n=1 Tax=Anaplasma
           marginale str. St. Maries RepID=Q5PAV2_ANAMM
          Length = 225

 Score =  159 bits (402), Expect = 1e-37,   Method: Composition-based stats.
 Identities = 40/172 (23%), Positives = 66/172 (38%), Gaps = 7/172 (4%)

Query: 38  LAEMGPQKLR-VLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQ 96
           L     +  R +LD G G G  A  M   G  V   D S   I+ A   A   G+  ++ 
Sbjct: 28  LQSSQRRGQRSLLDIGCGGGIFAESMVRLGFSVTGVDPSQASIEAASTHARVAGL--DIH 85

Query: 97  FIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLL 156
           +         ++     D++    V+E V D  S L+    +L+ GG+L L   N     
Sbjct: 86  YHCAHLDQFCANHPEVYDVVTLMEVVEHVTDLESCLENACRLLKRGGMLFLSTLNRTLKS 145

Query: 157 MHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
           M   +    +YV   +P+      S +    P++V   L   G  +   +G+
Sbjct: 146 MILAIVAA-EYVLRWVPRGTH---SWNKFVRPSEVCSMLRARGVIVQNISGM 193


>UniRef50_Q8TIA7 Phosphatidylethanolamine N-methyltransferase n=3 Tax=Methanosarcina
           RepID=Q8TIA7_METAC
          Length = 252

 Score =  159 bits (402), Expect = 1e-37,   Method: Composition-based stats.
 Identities = 45/216 (20%), Positives = 81/216 (37%), Gaps = 25/216 (11%)

Query: 9   IAEKFSRNIYGTTKGQLRQAILWQDL-DRVLAEMGPQKLR--VLDAGGGEGQTAIKMAER 65
           IA+ ++      T G+       + +  R+L    P   R  VLD G G G  A+  AE 
Sbjct: 7   IADYWNLRSSTYTNGENGFDAEERIIWRRMLENFLPPGQRLKVLDVGTGPGFLALLFAEM 66

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV 125
           GH+V   D+S  M+++A+  A+  GV   +   H  A+ +    +   DL++   +L  +
Sbjct: 67  GHEVTAVDISMGMLEKARNNAKTLGV--KVDLFHGDAEKLP-FEDCYFDLVVNKYLLWTL 123

Query: 126 ADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYP 185
             P   +Q    VL+PGG +  +  N         V     ++   +     +  S  + 
Sbjct: 124 PQPEIAVQEWMRVLKPGGRVFAIDGNWFNPRPDKKVK---RWITGVVNPDMNKNPSRSFF 180

Query: 186 ----------------RDPAQVYLWLEEAGWQIMGK 205
                             P  V +   + G++    
Sbjct: 181 NEFYGPIRKALPLYEDISPENVSVVFSKMGFENTAV 216


>UniRef50_B1KQ47 Ubiquinone biosynthesis O-methyltransferase n=3 Tax=Shewanella
           RepID=B1KQ47_SHEWM
          Length = 270

 Score =  158 bits (401), Expect = 1e-37,   Method: Composition-based stats.
 Identities = 51/233 (21%), Positives = 96/233 (41%), Gaps = 29/233 (12%)

Query: 6   FDDIAEKFSR--------NIYGTTKGQLRQAILWQDLDRVLAEMGP-QKLRVLDAGGGEG 56
           FD +AE++            +  T+    Q ++ +   R L +  P   L +LD G G G
Sbjct: 25  FDALAEEWRDPQGKFKHVLAFNLTRLTAIQMMIAEHFKRDLTQDIPFNDLTMLDIGCGVG 84

Query: 57  QTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLE------ 110
                ++++G  V   D S   ID A+Q AE   +  N+ + HC A+D+ +         
Sbjct: 85  LLCEPLSKQGAHVTGIDASCYNIDLARQHAEKNNI--NINYQHCLAEDLLAKQPINIANN 142

Query: 111 -------TPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAG 163
                     D++L   V+E V D +++++T   +++PGG+L +   N         + G
Sbjct: 143 QSDRIGSKHYDVVLNTEVIEHVEDQQALIKTCCELVKPGGILIMATLNRTIKSYVIGIIG 202

Query: 164 NFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLR 216
             +YV   +P          Y   P ++   +   G   +   G+  F+ + +
Sbjct: 203 A-EYVMRYLPIGTHDW---HYFVTPKEINTMISANGLTPITSQGM-SFNPFTK 250


>UniRef50_B9JTF4 Ubiquinone biosynthesis O-methyltransferase n=1 Tax=Agrobacterium
           vitis S4 RepID=B9JTF4_AGRVS
          Length = 260

 Score =  158 bits (401), Expect = 1e-37,   Method: Composition-based stats.
 Identities = 53/244 (21%), Positives = 92/244 (37%), Gaps = 17/244 (6%)

Query: 6   FDDIAEKFSR---------NIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEG 56
           F  +A ++            I       +R            +      LRVLD G G G
Sbjct: 25  FSAMAAEWWDPTGKFKPLHKINPVRLAYIRDKACENYQRDPRSNQPLSGLRVLDIGCGGG 84

Query: 57  QTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLI 116
             +  +A  G  V+  D SA+ I  A+  A   GVS  + +    A+ +A+      D++
Sbjct: 85  LLSEPIARMGADVLGADASAKNIGIAQTHAAQTGVS--VDYRAVTAEALAAAG-ESFDIV 141

Query: 117 LFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKK 176
           L   V+E VAD    + T  S++RPGG++ +   N         + G  +YV   +P+  
Sbjct: 142 LNMEVVEHVADVEYFISTCASMVRPGGIMLISTINRTLKAAALAI-GACEYVLRWLPRGT 200

Query: 177 KRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYC 236
            +    +    P ++   +  AG  +    GV  F+ +  + +   D     + L  R  
Sbjct: 201 HQY---EKLVRPEELEKPILGAGMNVSETVGV-FFNPFQNQWNLSTDTDVNYMMLTRRPT 256

Query: 237 RQEP 240
               
Sbjct: 257 STPE 260


>UniRef50_A0ZM88 3-demethylubiquinone-9 3-methyltransferase n=1 Tax=Nodularia
           spumigena CCY9414 RepID=A0ZM88_NODSP
          Length = 252

 Score =  158 bits (401), Expect = 1e-37,   Method: Composition-based stats.
 Identities = 38/212 (17%), Positives = 70/212 (33%), Gaps = 12/212 (5%)

Query: 1   MQDR---NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQ 57
           M+      +D  A+ +                        +     Q ++VLD G G G 
Sbjct: 1   MKKNDLEYYDLNADNWWTEGKVLNLSNHLNKYRIDFFSSYIPTW--QGIKVLDIGCGGGL 58

Query: 58  TAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLIL 117
            +  +A++   V   DLS + I  A+  A    +  N+ +    A+++        D +L
Sbjct: 59  ASETLAKQEACVTGIDLSLESIKVAQAHARKNHL--NIDYYWGFAENLP-FAAKKFDAVL 115

Query: 118 FHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKK 177
              VLE V D + V+     VL+  G+      N        M+    + +   +P    
Sbjct: 116 CCDVLEHVTDWQKVISEAHRVLKTNGLFFFDTINRSFKSKLIMI-WLLEDIVKQIPPGLH 174

Query: 178 RTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVR 209
                     P ++   +E  G   +   G  
Sbjct: 175 DW---HKFIKPEELTYTMENNGLNNVVIKGFD 203


>UniRef50_A0LNU5 3-demethylubiquinone-9 3-methyltransferase n=1 Tax=Syntrophobacter
           fumaroxidans MPOB RepID=A0LNU5_SYNFM
          Length = 258

 Score =  158 bits (401), Expect = 1e-37,   Method: Composition-based stats.
 Identities = 41/257 (15%), Positives = 82/257 (31%), Gaps = 17/257 (6%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQ---AILWQDLDRVLAEMGPQKLRVLDAGGGEGQ 57
           + +  +     ++     G     LR     + +    R L E+      +LD G G G 
Sbjct: 3   IDNEVYQTYGHEWWSENAGFNVFSLRYCMNPVRYGYFKRKLRELRLPGGTILDVGCGGGL 62

Query: 58  TAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLIL 117
            A + A  G  V   D + + ++ A++ A    +   + +     + +    +   D++ 
Sbjct: 63  LAEEFARDGFAVTGIDPATRSLEAARKHAADTNLE--IDYREGKGEALP-FPDGSFDIVA 119

Query: 118 FHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKK 177
              VLE V D   V+  +   LR GGV      N        ++  + D+        K 
Sbjct: 120 CCDVLEHVDDLGLVIGEVARTLRAGGVFCYDTVNRTWFSKLALIKISQDW--GFTSWSKP 177

Query: 178 RTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDY---------LREKHQQRDCYEAL 228
                +    PA++   +   G       G+    +          L++         A+
Sbjct: 178 NVHVWEKFIKPAELIAVMNRCGLANQELRGISARRNPLALIAGLHALKKGRLSNREMAAV 237

Query: 229 LELETRYCRQEPYITLG 245
             L      +  Y+   
Sbjct: 238 FALRESEDLRASYMGYA 254


>UniRef50_A4B9Z3 3-demethylubiquinone-9 3-methyltransferase n=2 Tax=unclassified
           Gammaproteobacteria RepID=A4B9Z3_9GAMM
          Length = 247

 Score =  158 bits (400), Expect = 2e-37,   Method: Composition-based stats.
 Identities = 42/214 (19%), Positives = 88/214 (41%), Gaps = 15/214 (7%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVL--------AEMGPQKLRVLDAGGGEG 56
            +  +A+ + +             +  + +            +E   Q L VLD G G G
Sbjct: 14  YYRRLADTWWQPDGPFWPLHQLNQLRTRWIAEQWRKRHPMADSEQPLQGLHVLDVGCGGG 73

Query: 57  QTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLI 116
             +  +A  G QV   D+ A+ I+ A++ A+A+ ++   + I   A  +    +   D++
Sbjct: 74  ILSEALARLGAQVHGVDVVARNIEVARRHAKAQNLAVTYECIETDA--LVRRGD-QYDIV 130

Query: 117 LFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKK 176
               V+E VA+    +    ++++PGG   +   N + L     + G  +Y+   +PK  
Sbjct: 131 FNMEVVEHVANVDLFMAQCNALVKPGGTQFVATINRNWLSFLIAIIGA-EYITGYLPKGT 189

Query: 177 KRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRV 210
            +       + P ++  +L   G ++  + GV V
Sbjct: 190 HQY---GKLQKPEEIRRYLALGGLKVTAREGVAV 220


>UniRef50_C0ZNJ7 Putative methyltransferase n=1 Tax=Rhodococcus erythropolis PR4
           RepID=C0ZNJ7_RHOE4
          Length = 274

 Score =  158 bits (399), Expect = 2e-37,   Method: Composition-based stats.
 Identities = 66/253 (26%), Positives = 112/253 (44%), Gaps = 11/253 (4%)

Query: 15  RNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDL 74
            +   +  G+LR  +   +LD  +   G   LRVLD GGG+G  +I +A  G+QV L D 
Sbjct: 16  AHWQSSPWGRLRYTVARANLDTYVG--GRSGLRVLDLGGGDGLESILLARNGNQVTLVDS 73

Query: 75  SAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA-SHLETPVDLILFHAVLEWVADPRSVLQ 133
           S  M+D A   A+A GVS +M F++    D+  S      D++L H VL+++      L 
Sbjct: 74  SPAMLDIASGRADAAGVSASMTFVNSEVLDLPRSIATGSFDVVLLHNVLQYLPQGIGALP 133

Query: 134 TLWSVLRPGGVLSLMFYNAHGLLMHNMVAGN-FDYVQAGMPKKKKRTLSPDYPRD---PA 189
            + + L  GG+ S++  N     +               + + + R+++ D         
Sbjct: 134 AVTAPLADGGIFSVISINKFSEPIAAAARRADPTEALNLLGESRYRSVTFDSDLTMFAAG 193

Query: 190 QVYLWLEEAG-WQIMGKTGVRVFHDYLREKHQ--QRDCYEALLELETRYCRQEPYITLGR 246
            +   +E  G +  +   G+R F D++    +    + Y AL  LE     + PY+   R
Sbjct: 194 DIIDAIEATGDFGDVNHYGIRCFSDFIAADDEKWDPEFYSALEALELASTARWPYMHTAR 253

Query: 247 YIHVTARKPQSKD 259
              +  R+  SKD
Sbjct: 254 LFQIIGRR-ASKD 265


>UniRef50_C5KJI6 3-demethylubiquinone-9 3-methyltransferase, putative n=5
           Tax=Perkinsus marinus ATCC 50983 RepID=C5KJI6_9ALVE
          Length = 312

 Score =  158 bits (399), Expect = 2e-37,   Method: Composition-based stats.
 Identities = 39/206 (18%), Positives = 79/206 (38%), Gaps = 15/206 (7%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQ---LRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQ 57
           + +  +DD++  +       T  +   +R     + L +      P K R LD G G G 
Sbjct: 44  IDNHLYDDVS-WWDEEEIVYTLRKTNVIRCPFFHRHLSK--GGKIPSKGRYLDVGCGGGL 100

Query: 58  TAIKMAE-RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLI 116
               MA   G+ +   D+S   + +A++         N+ +   +A D+    +   D +
Sbjct: 101 LTEDMASTYGYNITGIDISEASLQQAREHGRH---IPNLHYQVGSAYDIP-FPDNSFDGV 156

Query: 117 LFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKK 176
           +   VL+ + D R  +Q ++ VL+PGGV+     + +      +     + +   M    
Sbjct: 157 IISEVLDHLMDLRKAIQEIYRVLKPGGVVVFDTISRNFKSYLLVWLIAQE-ILQVMYNDT 215

Query: 177 KRTLSPDYPRDPAQVYLWLEEAGWQI 202
                      P ++   L E G+ +
Sbjct: 216 HDW---RLFITPEEMERLLSETGFVV 238


>UniRef50_D1RIV9 3-demethylubiquinone-9 3-O-methyltransferase n=1 Tax=Legionella
           longbeachae D-4968 RepID=D1RIV9_LEGLO
          Length = 231

 Score =  158 bits (399), Expect = 2e-37,   Method: Composition-based stats.
 Identities = 49/222 (22%), Positives = 86/222 (38%), Gaps = 17/222 (7%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLR--QAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIK 61
             F   A+ +       T+G LR    I    LD +   +    L VLD G G G     
Sbjct: 14  HKFAQHAKLWWD-----TEGPLRTLHDINGIRLDFIQQHVQLSHLNVLDVGCGGGILCET 68

Query: 62  MAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
           MA  G  V   D     I  A++ A+   +  N+ +   + +    +     D+I    +
Sbjct: 69  MANAGANVTGIDAEIDTILVAQEHAKGSHL--NVDYFCTSIEA---YKNPCFDVITCMEM 123

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLS 181
           LE V +P+ VLQ    +L+P G L L   +         +    +Y+   +PK+      
Sbjct: 124 LEHVQNPKLVLQHCRRLLKPKGFLFLSTISRTVKAYLTAIVAA-EYLLNLLPKQTHDY-- 180

Query: 182 PDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRD 223
            D    P+++       G++++   G+  ++  LR+     D
Sbjct: 181 -DKFIKPSELLAITRSLGFKLVDMKGMD-YNPLLRKASLGTD 220


>UniRef50_UPI000051ABE2 PREDICTED: similar to coenzyme Q3 homolog, methyltransferase n=2
           Tax=Apocrita RepID=UPI000051ABE2
          Length = 286

 Score =  157 bits (398), Expect = 3e-37,   Method: Composition-based stats.
 Identities = 42/224 (18%), Positives = 85/224 (37%), Gaps = 16/224 (7%)

Query: 5   NFDDIAEKFSRNIYG----TTKGQLRQAILWQDLDRV-----LAEMGPQKLRVLDAGGGE 55
           +F  +  K+               LR  ++   L  +        +  + +++LD G G 
Sbjct: 47  HFSKLHNKWWDVNGEIRPLHALNPLRIQLIRDGLANIGVKIECPYLPLEGIKILDVGCGG 106

Query: 56  GQTAIKMAERGHQVILCDLSAQMIDRAKQAA-EAKGVSDNMQFIHCAAQDVASHLETPVD 114
           G  +  +A  G  V   D S+++I  AKQ A     +   + +     +D A + +   +
Sbjct: 107 GLLSESLARIGADVTGIDASSELITAAKQHAVLDASLDGKLNYFQTIIEDFALNNKEVYN 166

Query: 115 LILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPK 174
            ++   V+E V +    L+   S L+PGG + L   N         +    + +   +PK
Sbjct: 167 AVVASEVIEHVNNKELFLKCCISSLKPGGSIFLTTINKTLPSWLGGIIAA-ERILKVVPK 225

Query: 175 KKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREK 218
                   +    P ++   LE  G +     G+  F++ L+ +
Sbjct: 226 GTHDW---NKFVTPTEMQSLLETYGCKTKLIHGM--FYNILKNE 264


>UniRef50_A7S2R8 Predicted protein n=1 Tax=Nematostella vectensis RepID=A7S2R8_NEMVE
          Length = 300

 Score =  157 bits (398), Expect = 3e-37,   Method: Composition-based stats.
 Identities = 35/185 (18%), Positives = 73/185 (39%), Gaps = 6/185 (3%)

Query: 25  LRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQ 84
           +++A+L    + + +       ++LD G G G  A  +A  G +V   D SA+    A +
Sbjct: 95  IKKAVLGVQGEMLTSSKPLDGFKMLDVGCGGGLLAEPLARLGAKVTGIDASARNTHVAMR 154

Query: 85  AAE-AKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGG 143
            A     ++  +Q+     + +A       D ++   V+E V +  S +  +  +L+P G
Sbjct: 155 HASLDPSLAGKLQYRCITVEQLAQEK-KVFDCVVSSEVIEHVTEKESFIGAISQLLKPRG 213

Query: 144 VLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIM 203
            L L   N         +    +Y+   +P         +     +++   L+E G +  
Sbjct: 214 SLILTTMNRTPQAYVLAIVAA-EYIAHAVPIGTHDW---NKFPKISELTELLQENGLETE 269

Query: 204 GKTGV 208
              G+
Sbjct: 270 DIQGL 274


>UniRef50_Q7Q8W1 AGAP010535-PA n=1 Tax=Anopheles gambiae RepID=Q7Q8W1_ANOGA
          Length = 266

 Score =  157 bits (398), Expect = 3e-37,   Method: Composition-based stats.
 Identities = 41/214 (19%), Positives = 82/214 (38%), Gaps = 17/214 (7%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMG------------PQKLRVLDAGG 53
           FD +++++               +    +   L ++G             + L +LD G 
Sbjct: 29  FDQLSKRWWEPNGPMILLHRLNKLRVPMVVEGLIKVGKLDRKQRYTTDALKGLNILDVGC 88

Query: 54  GEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAK-GVSDNMQFIHCAAQDVASHLETP 112
           G G  A  +A+    V+  D +  +I+ AK  AEA+  + D   +   + ++        
Sbjct: 89  GGGIYAEALAKLHANVVGIDPARHLIEVAKAHAEAQSDIKDRCHYYEQSMEEHWQGAANK 148

Query: 113 VDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGM 172
            D+++    +E V D  S+L+ +  VL+PGG + +  +N         V    + +   +
Sbjct: 149 YDVVVLSETIEHVVDKSSLLKHVAEVLKPGGSVFISTWNKTSWSWLLAVV-VLENIMKRL 207

Query: 173 PKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKT 206
           PK        D    P +    LE  G + + + 
Sbjct: 208 PKGSHDY---DKFVSPEETEAILEAYGCRTIEQR 238


>UniRef50_B4RRL2 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase
           n=1 Tax=Alteromonas macleodii 'Deep ecotype'
           RepID=B4RRL2_ALTMD
          Length = 250

 Score =  157 bits (398), Expect = 3e-37,   Method: Composition-based stats.
 Identities = 43/212 (20%), Positives = 86/212 (40%), Gaps = 16/212 (7%)

Query: 6   FDDIAEKFSRNI----YGTTKGQLRQAILWQDLDRVLAEMGPQK----LRVLDAGGGEGQ 57
           FD +A+ +              + R  ++   ++    +         L ++D G G G 
Sbjct: 21  FDALADSWWDPSGKYKTALEFNRARLTVIKTQIENHFGKGNLPPDYSALSIIDIGSGGGL 80

Query: 58  TAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLIL 117
            +  +A  G +V   D S+  ++ AK+ A   GV  ++++ H      A       D+++
Sbjct: 81  ISEPLAALGAKVTGIDASSVSVEVAKRHALKSGV--DVEYKHM-LSSEAVMTGQQYDVVI 137

Query: 118 FHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKK 177
              V+E V D R ++    S+++PGG+L L   N         + G  +YV   +P    
Sbjct: 138 NAEVVEHVPDQRQLINECASLVKPGGLLILATLNRTIKSYVIAIVGA-EYVMRYLPVGTH 196

Query: 178 RTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVR 209
                     P ++  W+ +  + +  +TG+R
Sbjct: 197 DW---RKFVKPQELQAWVGD-RFALKHQTGMR 224


>UniRef50_A8MFN6 Methyltransferase type 11 n=1 Tax=Alkaliphilus oremlandii OhILAs
           RepID=A8MFN6_ALKOO
          Length = 268

 Score =  157 bits (397), Expect = 4e-37,   Method: Composition-based stats.
 Identities = 53/275 (19%), Positives = 114/275 (41%), Gaps = 28/275 (10%)

Query: 1   MQD---RNFDDIAEK-FSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEG 56
           M +   + +DD AE  ++R     +       + +     ++ +  P+   ++D G G G
Sbjct: 1   MTEEVRKYYDDFAENEWNRLNNSYS------RVEYASTLYLIEKYFPRTGNIIDIGSGPG 54

Query: 57  QTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLI 116
           + ++++ +RG+ V L DLS   ++ AK+  E   +     +   +A ++    +   D +
Sbjct: 55  RYSLELLKRGYHVSLLDLSKNELEIAKKKIEESNLKAE-HYYCKSALELDFLEDEFFDGV 113

Query: 117 LFHAVLEWV---ADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMV--------AGNF 165
           L    L  +    +   VL+  + +L+ GGV  + + N  G L  ++           +F
Sbjct: 114 LVMGPLYHLHGAQEREKVLKDTYRILKKGGVALISYINTWGALKASVSEFPESFEDEAHF 173

Query: 166 D-YVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQ--- 221
           + Y++  +    + + +  +   P      +EE+G+ I+   G   F   L  + Q    
Sbjct: 174 ERYIKGDLRFSSEESFTATFFTTPPLALKEVEESGFTIVSYAGAESFLSGLNIQLQNLHK 233

Query: 222 --RDCYEALLELETRYCRQEPYITLGRYIHVTARK 254
                Y+  LE   +YC    Y     ++H+  +K
Sbjct: 234 YMPHVYKNYLEAAPKYCELPQYRDATEHLHIIVQK 268


>UniRef50_Q5WCE8 S-adenosylmethionine (SAM)-dependent methyltransferase n=3
           Tax=Bacillus RepID=Q5WCE8_BACSK
          Length = 261

 Score =  156 bits (396), Expect = 5e-37,   Method: Composition-based stats.
 Identities = 58/276 (21%), Positives = 105/276 (38%), Gaps = 41/276 (14%)

Query: 1   MQDRN-FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLR-VLDAGGGEGQT 58
           M  R+ F+   + ++ N+Y       R A + +  + +L  + P K   +LD G G G  
Sbjct: 1   MNKRSPFN---DHWNSNLYD-----NRHAFVSKFGNHLLELLQPTKKEAILDLGSGTGDL 52

Query: 59  AIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILF 118
           A ++A+ G  V   D S+ M+ +A+          ++ F    A ++        D +L 
Sbjct: 53  ANELAKLGAVVTGVDQSSNMVAKARSK------YPHLLFDMADATNLPFT--ETFDAVLS 104

Query: 119 HAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKR 178
           +AVL WV D  + L+++W  L+PGG      +   G +            QAG P   K+
Sbjct: 105 NAVLHWVLDAEAALKSIWRALKPGGRFV-AEFGGKGNVETITTELVAQIKQAGCPYSSKQ 163

Query: 179 TLSPDYPRDPAQVYLWLEEAGWQI---------MGKTGVRVFHDYLR-------EKHQQR 222
              P Y     +    +E+ G+ +             G   F ++L         +  ++
Sbjct: 164 F--PWYFPSIGEYTSLMEKTGFSVSFARLYERPTPLEGADGFRNWLEMFANPFFNEIDEQ 221

Query: 223 DCYEALLELETRYC--RQEPYITLGRY--IHVTARK 254
           D    + + E        E    +  Y  + V   K
Sbjct: 222 DKQAIIAKTEIALQPVLMEEGQWIADYKRLMVVGYK 257


>UniRef50_Q2FPT3 UbiE/COQ5 methyltransferase n=1 Tax=Methanospirillum hungatei JF-1
           RepID=Q2FPT3_METHJ
          Length = 252

 Score =  156 bits (395), Expect = 6e-37,   Method: Composition-based stats.
 Identities = 45/231 (19%), Positives = 93/231 (40%), Gaps = 15/231 (6%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
            +++ ++ F +++         +  LW++  R +  +G  K  VLD G G G  AI +AE
Sbjct: 18  YWNERSKTFDQDVGHGAD--HHECQLWKNQLRTI--IGDDKKDVLDFGTGTGMIAINLAE 73

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
            GH V   DL  +M+D A + AE+K +S  ++F+   A++     +   D+++   +L  
Sbjct: 74  LGHSVTGIDLCEEMLDIANRKAESKDLS--IRFLLGDAEN-PEFPDRMFDVVICRHLLWT 130

Query: 125 VADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRT----- 179
           +  P   ++    + RPGGV+  +  +       +      +  ++   K  ++T     
Sbjct: 131 LPHPDVAIREWSRICRPGGVIIAIDGHQEPKDYFHHSDEKDESEKSDQEKLWEQTYSKEI 190

Query: 180 ---LSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEA 227
              L          +       G   +    ++   +Y +  H   D    
Sbjct: 191 TMQLPNGDQLTIESLKELFTTNGLGDVQSKNLKDIAEYHQRLHSASDHERQ 241


>UniRef50_A1HPJ4 Methyltransferase type 11 n=1 Tax=Thermosinus carboxydivorans Nor1
           RepID=A1HPJ4_9FIRM
          Length = 229

 Score =  156 bits (395), Expect = 7e-37,   Method: Composition-based stats.
 Identities = 40/227 (17%), Positives = 76/227 (33%), Gaps = 20/227 (8%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
             F ++A K+    + T  GQ       + +  +      Q + V D G G G    +  
Sbjct: 2   NYFQELAAKYDA-WFQTPHGQYVYRYEREMIFDLAE--VQQDMYVADVGCGTGIYTNEFC 58

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
             G +V+  D+S +M+  A +  +  G  + + F+   A  +    +   D+++    +E
Sbjct: 59  AAGARVVGIDISPEMLAIAAEKNKTWG--NRVSFVTADAAALP-FPDNAFDMVVSITAME 115

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFY-NAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSP 182
           +  +PR  L  +  +LRPGG + +    N     M   +   F           +   S 
Sbjct: 116 FFEEPRRCLHEMHRILRPGGRMIVATLGNWSLWSMQRRLKTLF----------TRTIFSH 165

Query: 183 DYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQ-RDCYEAL 228
                   +   L      I    G      +      +  D  E  
Sbjct: 166 TRFYSIRDIARLL--NPITISEWRGGIFIPPFAPAALIRHPDKLERW 210


>UniRef50_Q465A3 UbiE/COQ5 methyltransferase n=3 Tax=Methanomicrobia
           RepID=Q465A3_METBF
          Length = 230

 Score =  156 bits (395), Expect = 7e-37,   Method: Composition-based stats.
 Identities = 45/233 (19%), Positives = 88/233 (37%), Gaps = 23/233 (9%)

Query: 1   MQDR---NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQ 57
           M+D+   +++ I+  + +         L + IL      +      +KL VLD G G G 
Sbjct: 1   MKDKITAHWNKISPNYRKMYRD----HLDEEILLMQNLFLDKLPAGKKLNVLDIGTGPGI 56

Query: 58  TAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLIL 117
            A   A  GH V   D+S +M+ RAK+ A+ + +S  ++F+    + +        D+I+
Sbjct: 57  QAFVFAGMGHNVTALDISEEMLARAKEEAKNRNLS--IKFVEGDGEKLP-FENNTFDIIV 113

Query: 118 FHAVLEWVADPRSVLQTLWSVLRPGGVLSLMF-----YNAHGLLMHNMVAGNFDYVQAGM 172
              +L  + D          VL P G +  +             ++N    N D +   +
Sbjct: 114 NMHLLWTLTDHDKFFSECCRVLVPEGRILAIDGQWFQPGYVPNRIYNQEERNHDELIEYL 173

Query: 173 PKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCY 225
           P              P  +   +E  G+  +    +  + +Y++    +   Y
Sbjct: 174 PLYDSN--------SPEMITTIMENNGFSEVSWKSLPEYAEYMKRCDPEGYDY 218


>UniRef50_Q88SI6 Menaquinone biosynthesis methyltransferase ubiE n=6
           Tax=Lactobacillales RepID=UBIE_LACPL
          Length = 237

 Score =  156 bits (395), Expect = 7e-37,   Method: Composition-based stats.
 Identities = 45/225 (20%), Positives = 77/225 (34%), Gaps = 24/225 (10%)

Query: 1   MQDRN-------FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGG 53
           M +R        FD IA  + R     + G  R    W+        +      VLD   
Sbjct: 1   MANRYLHNVQGLFDTIAPNYDRMNNIISLGTHRH---WRKQTMAQIHLA-SNAHVLDLCC 56

Query: 54  GEGQTAIKMA---ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLE 110
           G G   I +A   +   +VI  D SA M+  A+Q    + V+D +      A  +    +
Sbjct: 57  GTGDWTIALAKELQAPGEVIGLDFSAPMLKLAQQKVTQQQVADRVWLRRGNAMHLP-FKD 115

Query: 111 TPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYN-AHGLLMHNMVAGNFDYVQ 169
              DL+     L  + D    L  ++ VL+PG  L  +  +     L+  +    F  V 
Sbjct: 116 NTFDLVTIGFGLRNLPDKAQALTEIYRVLKPGARLVCLETSQPDQPLIKPVWQWYFTKVV 175

Query: 170 AGMPK--------KKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKT 206
               +              +  +     Q+    ++AG+Q +   
Sbjct: 176 PLFGRLFAHQYQEYSYLQETTRHFASYQQLATMFQQAGFQNVHFQ 220


>UniRef50_A8M0L9 Methyltransferase type 12 n=1 Tax=Salinispora arenicola CNS-205
           RepID=A8M0L9_SALAI
          Length = 269

 Score =  156 bits (395), Expect = 7e-37,   Method: Composition-based stats.
 Identities = 68/269 (25%), Positives = 120/269 (44%), Gaps = 17/269 (6%)

Query: 1   MQDR------NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGG 54
           M DR       FD  AE +      T  G+LR  ++   +DR +  +     RVLDAGG 
Sbjct: 1   MSDRPQATPEVFDRRAEAWDA-WQETPWGRLRYRLVAHTVDRAVRRLSG-TCRVLDAGGA 58

Query: 55  EGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASH---LET 111
           +G  ++++A+RGH V + D +  ++ RA+  A A GV   ++ +     +V       E 
Sbjct: 59  DGADSLRLAQRGHHVTIVDHAPALLARARARARAAGVDHLVRTVCAGVDEVPELRRTGEV 118

Query: 112 PVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAG 171
             DL+L H VL ++ D  + +  L + +RPGG++S++  N    L+   V  +      G
Sbjct: 119 GFDLVLCHNVLHYLPDTPAAVAGLATAVRPGGLISVLAPNPAMDLLAIAVRRSSPAEAFG 178

Query: 172 MPKKKKRTLSPDYP----RDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQ--RDCY 225
           +   +              +   V   LE++G  +  + G+R   D +     +     +
Sbjct: 179 LLDAEALFSETFEHDMLRLEAEDVAAALEKSGCTVTDRFGIRCATDLIANDELKHTPAFF 238

Query: 226 EALLELETRYCRQEPYITLGRYIHVTARK 254
             L  LE   C +EPY+ + R+  + A +
Sbjct: 239 ADLERLELALCDREPYLRMARFWQLLATR 267


>UniRef50_Q235E0 Ubiquinone biosynthesis O-methyltransferase family protein n=1
           Tax=Tetrahymena thermophila SB210 RepID=Q235E0_TETTH
          Length = 274

 Score =  156 bits (394), Expect = 8e-37,   Method: Composition-based stats.
 Identities = 39/239 (16%), Positives = 94/239 (39%), Gaps = 16/239 (6%)

Query: 4   RNFDDIAEKF---SRNIYGTTKGQLRQAILWQDLDR-----VLAEMGPQKLRVLDAGGGE 55
            +F  I + +   S      +    R   + + +          ++  + L++LD G G 
Sbjct: 40  NHFSQIKDWWKSGSEMAPLYSYNFARVNFIKEFMKDFNNQNYHLKLPLKNLQILDVGCGG 99

Query: 56  GQTAIKMAERGHQVILCDLSAQMIDRAKQAAE-AKGVSDNMQFIHCAAQDVASHLETPVD 114
           G  +  +   G  V   D +   I  A    +  + +   + +    A++++S      D
Sbjct: 100 GLLSESLCRLGANVTGLDANENSISIANNHKKLDQFLEQKLNYKLGTAEELSSQ-NIQYD 158

Query: 115 LILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPK 174
           L+    V+E + D    + TL  ++RPGG++ L            ++ G  +Y+   +PK
Sbjct: 159 LVTCMEVIEHIQDKEQFIATLSQLVRPGGMIFLSTMEKTRESYLKLILGA-EYIAKLVPK 217

Query: 175 KKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV--RVFHDYLREKHQQRDCYEALLEL 231
                   +   +   +   LE+ G++I+   G    + ++ + + + + +   + ++L
Sbjct: 218 GTHDW---NKFINSEDLSALLEDNGFKILKIQGFSYDIINNQMEKSNNKMNYLISAIKL 273


>UniRef50_B8EI29 3-demethylubiquinone-9 3-methyltransferase n=1 Tax=Methylocella
           silvestris BL2 RepID=UBIG_METSB
          Length = 256

 Score =  156 bits (394), Expect = 8e-37,   Method: Composition-based stats.
 Identities = 49/233 (21%), Positives = 83/233 (35%), Gaps = 22/233 (9%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVL--------------AEMGPQKLRVLDA 51
           FD I E +               +    L  ++              A    + LR+LDA
Sbjct: 20  FDRIGEDWWSADGPMAALHKLNPVRVAYLRDLMSRHFRVEGLPRDRYAPRPLEGLRILDA 79

Query: 52  GGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLET 111
           G G G  A  +A  G +V   D + + I+ A++ AE  G+S  + +     + ++     
Sbjct: 80  GCGAGLLAEPLARLGARVTAIDPAPRNIEVARRHAEKSGLS--IDYRMTTIEALSGEA-A 136

Query: 112 PVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAG 171
             D +L   VLE V D    ++   +++RPGG++     N         + G  +YV   
Sbjct: 137 TFDAVLAMEVLEHVLDVAGFVRCCGALVRPGGLMFAATLNRTLKSFAFAIVGA-EYVLGW 195

Query: 172 MPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDC 224
            P+             P ++   +  A      +TGV VF           D 
Sbjct: 196 APRGTHDW---RRFISPRELARAMAAADLSAFDETGV-VFDPLQGGWRLAHDT 244


>UniRef50_B2S828 3-demethylubiquinone-9 3-methyltransferase n=46 Tax=Proteobacteria
           RepID=UBIG_BRUA1
          Length = 248

 Score =  156 bits (394), Expect = 8e-37,   Method: Composition-based stats.
 Identities = 49/239 (20%), Positives = 94/239 (39%), Gaps = 17/239 (7%)

Query: 5   NFDDIAEKFSRNIY---------GTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGE 55
           +F  IA ++               T    +++ +  +      A    + LR LD G G 
Sbjct: 16  HFSRIAAQWWDPQGKFRPLHKFNPTRLAYIKEKVCAKFNRDPNAPRPLEGLRFLDIGCGG 75

Query: 56  GQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDL 115
           G     MA  G  VI  D SA  I+ AK  A    +  ++ +    A+ +A       D+
Sbjct: 76  GLLCEPMARLGATVIGADASATNIEVAKIHAAQSSL--DIDYRATTAEALAD-AGEKFDV 132

Query: 116 ILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKK 175
           +L   V+E V+D    +    ++++PGG++ +   N         + G  +YV   +P+ 
Sbjct: 133 VLNMEVVEHVSDVDLFMSATSAMVKPGGLMFVATINRTLKAYGLAIIGA-EYVLRWLPRG 191

Query: 176 KKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETR 234
             +    +    P ++     +A  +++ K GV  ++      ++ RD     + L  R
Sbjct: 192 THQY---EKLVRPEELEAAFSKADLRLIDKLGV-TYNPLADSWNRSRDMDVNYMVLAER 246


>UniRef50_Q467Y8 Methyltransferase n=2 Tax=Methanosarcina RepID=Q467Y8_METBF
          Length = 248

 Score =  155 bits (393), Expect = 1e-36,   Method: Composition-based stats.
 Identities = 42/216 (19%), Positives = 93/216 (43%), Gaps = 18/216 (8%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
             +   +E +S  I   ++ +      W+++     +   + L +LD G G GQ A+  A
Sbjct: 9   NYWGYRSETYSTGIVEQSEEEW---ATWKNILSSTVD-RREHLEILDVGTGPGQLALMFA 64

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
           E GH V   DLS +M+D+A++ A  + +  ++ FI   A+++    +   D++    +L 
Sbjct: 65  ELGHHVTAVDLSTRMLDKARKNALKRSL--DINFIQGDAENL-QLPDMQFDVVSSKFLLW 121

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGL-LMHNMVAGNFDYVQAGMPKKKKRTLS- 181
            + DP+  L     VL+  G++  +  +     +    +    D +++   +      + 
Sbjct: 122 TLPDPQKALSEWKRVLKKDGMIIAIDGDWFNSGIFLKSIRTISDGIRSIKERNFHNPFNQ 181

Query: 182 ---------PDYPRDPAQVYLWLEEAGWQIMGKTGV 208
                    P Y   P +V+ +L + G++ +    +
Sbjct: 182 HYNPIKKDLPLYSLKPDRVFRFLNDTGFEKINIERM 217


>UniRef50_Q1JXN0 Methyltransferase type 11 n=1 Tax=Desulfuromonas acetoxidans DSM
           684 RepID=Q1JXN0_DESAC
          Length = 264

 Score =  155 bits (393), Expect = 1e-36,   Method: Composition-based stats.
 Identities = 52/264 (19%), Positives = 97/264 (36%), Gaps = 32/264 (12%)

Query: 11  EKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQK-LRVLDAGGGEGQTAIKMAERGHQV 69
           +++S+      + Q     +  DLD +L  + PQK  +VLD   G G TA+ +A    QV
Sbjct: 12  DQYSQVGDAYVRSQTHAKGV--DLDYLLNMVQPQKDWKVLDVATGGGHTALILAPYVQQV 69

Query: 70  ILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPR 129
           I  DL+  M++ AK+    +    N+ F    A+++    +   DL+            +
Sbjct: 70  IAVDLTPNMVETAKKFVCDEKGQTNVTFQLADAENLP-FEDGSFDLVTCRIAAHHFPACQ 128

Query: 130 SVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPA 189
             +     VL+ GG+L++  +       H +    F+ +         R  S        
Sbjct: 129 KFIAESVRVLKQGGLLAVQDHVLPAEENHALYVDQFERL---------RDPSHFRAYSEQ 179

Query: 190 QVYLWLEEAGWQIMGKTGV---RVFHDYLREKHQQRDCYEALLEL-----ETRYCRQEPY 241
           Q     E  G Q+     +     F D+ +  +   +  + L+ +           Q+P+
Sbjct: 180 QWRQMFELGGLQVQQTRQLTKRHNFIDWAKRMNCTEETLDELVAMMKNAPNAVKAWQKPF 239

Query: 242 IT-----------LGRYIHVTARK 254
                        +  +I V  RK
Sbjct: 240 PDADHFGGIETSFVNHHIIVVGRK 263


>UniRef50_Q2GKA5 3-demethylubiquinone-9 3-methyltransferase n=7 Tax=Anaplasma
           RepID=Q2GKA5_ANAPZ
          Length = 236

 Score =  155 bits (393), Expect = 1e-36,   Method: Composition-based stats.
 Identities = 40/204 (19%), Positives = 81/204 (39%), Gaps = 8/204 (3%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           F ++A ++      +   ++    + Q +   L E      R+LD G G G     MA  
Sbjct: 12  FSNLASEWWDGESFSALHRINPLRV-QYILENLQEATNSGKRLLDIGCGGGLICEAMARL 70

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLE-TPVDLILFHAVLEW 124
           G  V   D   + I+ A+Q A  +G+  ++++     +      E +  D+I    V+E 
Sbjct: 71  GFSVTGVDPCREGIEAARQHAAIEGL--DIEYHFTDIESFIHSSECSSYDIITLMEVVEH 128

Query: 125 VADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDY 184
           + D    L +   +L+PGG+L +   N     M        +Y+   +P    +      
Sbjct: 129 IPDLTEFLSSSCKLLKPGGMLFISTLNRTIKSMLLGKIAA-EYILRMVPPGTHQW---KK 184

Query: 185 PRDPAQVYLWLEEAGWQIMGKTGV 208
              P++++  L ++   +    G+
Sbjct: 185 FVKPSEIHDALLKSRVLVKDIKGI 208


>UniRef50_Q0S6F7 3-demethylubiquinone-9 3-O-methyltransferase n=3
           Tax=Actinomycetales RepID=Q0S6F7_RHOSR
          Length = 279

 Score =  155 bits (392), Expect = 2e-36,   Method: Composition-based stats.
 Identities = 46/253 (18%), Positives = 89/253 (35%), Gaps = 21/253 (8%)

Query: 1   MQDRNFDDIAEKFSR-----NIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGE 55
           + +  ++ + E +       N+   +    R A   + L   +     + LR LD G G 
Sbjct: 6   IDNDVYNRVGESWWEEDNPLNLLHGSLTPGRFAYFRKVLGETVGR-DHRGLRALDVGSGG 64

Query: 56  GQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDL 115
           G  A +    G +V   D S   +D A++ A   G + ++++   + + +    +   D+
Sbjct: 65  GFLAEEFTRIGFRVTGIDPSPVSVDTARRHAA--GSALDIEYRIGSGEHLPV-PDATFDV 121

Query: 116 ILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKK 175
                VLE V+D   V+     VL+PGG+      N         +    ++    M   
Sbjct: 122 AYCCDVLEHVSDLDGVIAETSRVLKPGGLYLFDTINRTFASKLVAIKIMQEWRMTRMFDT 181

Query: 176 KKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRY 235
                       PA++   +E  G ++    G+            +      LL+L    
Sbjct: 182 PIH--DWSMCIRPAELAPIMERHGLRLGEIVGL----------GPRSKNPLRLLDLARAG 229

Query: 236 CRQEPYITLGRYI 248
             +  Y  L R +
Sbjct: 230 GTRLSYGELSRRL 242


>UniRef50_C6P0T7 Methyltransferase type 11 n=1 Tax=Sideroxydans lithotrophicus ES-1
           RepID=C6P0T7_9PROT
          Length = 270

 Score =  155 bits (392), Expect = 2e-36,   Method: Composition-based stats.
 Identities = 36/204 (17%), Positives = 79/204 (38%), Gaps = 14/204 (6%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           ++ +A+ ++       +    +AI   +L             VLD   G G  A+++A++
Sbjct: 12  WNLVADGYAETTMLVFEQFADEAIAASNL--------KPNSTVLDVACGPGTLALRLAQQ 63

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV 125
             QV   D S  M+   +   E  G   N+      AQ +  + +   D       L + 
Sbjct: 64  AGQVHGIDFSEAMLAIFRNKIEQAGHR-NIALHCGDAQTLP-YADATFDAAFSLFGLMFF 121

Query: 126 ADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHN-MVAGNFDYVQAGMPKKKKRTLSPDY 184
            D +     ++  L+PGG +++  +           + G    ++  +P+ ++   + + 
Sbjct: 122 PDRQKGFAEIYRTLKPGGSIAITSWAPVDQSPAMQTMFGALRAIKPDLPQPQRSVATLEN 181

Query: 185 PRDPAQVYLWLEEAGWQIMGKTGV 208
              P +    +EEAG++ +    V
Sbjct: 182 ---PQRFRQEMEEAGFRYIEIRSV 202


>UniRef50_B2J5L2 Methyltransferase type 11 n=1 Tax=Nostoc punctiforme PCC 73102
           RepID=B2J5L2_NOSP7
          Length = 265

 Score =  154 bits (391), Expect = 2e-36,   Method: Composition-based stats.
 Identities = 45/218 (20%), Positives = 80/218 (36%), Gaps = 18/218 (8%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           +D  A+ +   +           IL  D            L VLDAG G G  A ++  +
Sbjct: 18  WDRRAKDWDIPVGDDGDS---NRILNSDPVLWSFAGNVAGLSVLDAGCGTGYLARQLCLK 74

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV 125
           G  V   D S QMI+ AK  A    +  ++ F   +  ++ S  +   D+I+ + VL  +
Sbjct: 75  GASVTGIDFSPQMIEIAKFRASQNNL--DIDFHLDSCTELKSLPDEQFDMIVSNYVLMDL 132

Query: 126 ADPRSVLQTLWSVLRPGGVLSL------------MFYNAHGLLMHNMVAGNFDYVQAGMP 173
            D    ++    VL+P G+  L               N  G + ++  +  F+  Q    
Sbjct: 133 LDLEGAIRAFNRVLKPSGIAILVFSHPCFPQGNSTTVNEDGTVSYSWASSYFERTQHNDE 192

Query: 174 KKKKRTLSPDYPRDP-AQVYLWLEEAGWQIMGKTGVRV 210
                T    +   P +  +   + AG+ +      R+
Sbjct: 193 PWNHFTTPFIWFHRPLSDYWKVFKAAGFSVDEFEEPRI 230


>UniRef50_B4V3L4 Methyltransferase n=17 Tax=Streptomyces RepID=B4V3L4_9ACTO
          Length = 235

 Score =  154 bits (391), Expect = 2e-36,   Method: Composition-based stats.
 Identities = 66/232 (28%), Positives = 104/232 (44%), Gaps = 9/232 (3%)

Query: 32  QDLDRVLAEMGPQK--LRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEA- 88
           + +D  +A+  P    LRVLD G G+G  A+++A  GH+V   +    M+D A+ A    
Sbjct: 3   RQVDEQIAQRFPVGQRLRVLDVGMGQGTQALRLARAGHKVTGLEKDPGMLDVARAALAGE 62

Query: 89  -KGVSDNMQFIHCAAQDV-ASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLS 146
             G+ D ++ I    ++  A  L    D++L H VL +V +P ++L  L  +L PGG+LS
Sbjct: 63  PAGIQDRVELIEGDGRETGAHFLPGSFDIVLCHGVLMYVPEPDAMLAGLARMLAPGGLLS 122

Query: 147 LMFYNAHGLLMHNMVAGNFDYVQAGMP--KKKKRTLSPDYPRDPAQVYLWLEEAGWQIMG 204
           L+  N   L M   + G++    A         R          + +   L   G  +  
Sbjct: 123 LLVRNGDALAMRPGLDGDWSGALAAFDTTDYTNRLGLDVRADRLSGLTATLSGIGAPLQS 182

Query: 205 KTGVRVFHDYLR--EKHQQRDCYEALLELETRYCRQEPYITLGRYIHVTARK 254
             GVRVF D     E+    D  E LL  E R  R +PY  +   +H+   +
Sbjct: 183 WYGVRVFTDGTEAGEQLPPEDELERLLAAEERAGRSDPYRGVAALLHLCGVR 234


>UniRef50_C9L9K2 SmtA protein n=6 Tax=Bacteria RepID=C9L9K2_RUMHA
          Length = 564

 Score =  154 bits (390), Expect = 3e-36,   Method: Composition-based stats.
 Identities = 46/202 (22%), Positives = 81/202 (40%), Gaps = 14/202 (6%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
            +   ++ F        + +L   I  + L  +L  +  +KL++LD G G G   I MA+
Sbjct: 334 YWTKRSDSF----QEQRRAELHDDIAQRWLKEILQYVPKKKLKILDVGCGSGFFTILMAQ 389

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
           +GH+VI  DL+A MI RAK+ A  +    +  F    A+++    +   D+++   +   
Sbjct: 390 QGHEVIGVDLTADMITRAKELAAEE--KADCTFQVMDAENL-EFADEAFDMVISRNLTWT 446

Query: 125 VADPRSVLQTLWSVLRPGGVLS-------LMFYNAHGLLMHNMVAGNFDYVQAGMPKKKK 177
           + D          VL+ GG L        +   +    L  N       +      ++ K
Sbjct: 447 LPDAERAYSEWLRVLKKGGCLLNFDANYGISDCSDTSQLPQNHAHNQLGFELLQECEEIK 506

Query: 178 RTLSPDYPRDPAQVYLWLEEAG 199
           R L     + PA     L + G
Sbjct: 507 RQLPISSYQRPAWDVGALGKLG 528


>UniRef50_C8Q6G5 Methyltransferase type 11 n=1 Tax=Pantoea sp. At-9b
           RepID=C8Q6G5_9ENTR
          Length = 287

 Score =  154 bits (389), Expect = 3e-36,   Method: Composition-based stats.
 Identities = 48/254 (18%), Positives = 97/254 (38%), Gaps = 18/254 (7%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
           N D  A  +         G+L + IL     +        +  VLD   G G+ A   AE
Sbjct: 22  NKDGAAWHYWHATLERWYGELTRQILDSAFIQ-------PRQHVLDIAAGAGEPAFSAAE 74

Query: 65  RGH---QVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
           R      V+  D+S  +I  A+QAA  +G++  +       + ++   +   D ++    
Sbjct: 75  RVGLEGYVLATDISDGIIALARQAASDRGLT-QVATRVMDGEVLS-LPDASFDAVICRLG 132

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLS 181
           L ++  P + L+    VL+PGG +++  ++         +  +    +A +P        
Sbjct: 133 LMYMPHPGAALREWHRVLKPGGHVAVAVFSTADRNSWGAIPASIIRRRAQLPPPVAGQPG 192

Query: 182 PDYPRDPAQVYLWLEEAGWQIMGKTGVRVFH------DYLREKHQQRDCYEALLELETRY 235
           P     P  +     +AG+  +  + V V H      +Y+R   +    + A++      
Sbjct: 193 PFSLGYPEVLQRLFIQAGFSNLSISTVLVPHRAASATEYVRVAREAFGGFNAMMASLPCT 252

Query: 236 CRQEPYITLGRYIH 249
            R+  +  +   +H
Sbjct: 253 ERESAWHEIETSLH 266


>UniRef50_C9NJ50 Methyltransferase type 12 n=8 Tax=Streptomyces RepID=C9NJ50_9ACTO
          Length = 252

 Score =  154 bits (389), Expect = 4e-36,   Method: Composition-based stats.
 Identities = 64/245 (26%), Positives = 106/245 (43%), Gaps = 10/245 (4%)

Query: 20  TTKGQLRQAILWQDLDRVLAEMGPQKLR----VLDAGGGEGQTAIKMAERGHQVILCDLS 75
             +  LR A++W+ L   L        R    VLD GGG G  A+ +A  GH+V + D S
Sbjct: 6   RPRASLRTAVVWEVLKDALERRVKATGREALDVLDTGGGTGNFAVPVARLGHRVTVVDPS 65

Query: 76  AQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLE-TPVDLILFHAVLEWVADPRSVLQT 134
              +   ++ A+  GV+D ++ +      +   ++    D +L H VLE+V DP   ++ 
Sbjct: 66  PNALFALERRADEAGVADRVRGVQGDILGLFEVVDRAGYDAVLCHGVLEYVDDPAEGVRN 125

Query: 135 LWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPD---YPRDPAQV 191
               LRP G LSL+     G ++   +AG+F   +  +     R  + D         Q+
Sbjct: 126 AVDALRPSGALSLLGAGLGGAVLARALAGHFAEARQALTDPDGRWGAGDPVPRRFTADQL 185

Query: 192 YLWLEEAGWQIMGKTGVRVFHDYLRE--KHQQRDCYEALLELETRYCRQEPYITLGRYIH 249
              ++ AG ++    GVRVF D +       +    E LL LE        + ++   +H
Sbjct: 186 TGLVDAAGVEVGAVHGVRVFADLVPGVLVDTEPGAMEELLRLEAAVAELPAFHSVATQLH 245

Query: 250 VTARK 254
           V   K
Sbjct: 246 VLGEK 250


>UniRef50_Q46D00 UbiE/COQ5 methyltransferase n=2 Tax=Methanosarcina
           RepID=Q46D00_METBF
          Length = 253

 Score =  154 bits (389), Expect = 4e-36,   Method: Composition-based stats.
 Identities = 49/246 (19%), Positives = 96/246 (39%), Gaps = 17/246 (6%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
           R +D  +E +        K ++ +   W+++ + L  + P +L+VLD G G  +  +  A
Sbjct: 14  RIWDVSSETYDSYEGHGIKSEVEREA-WKNVFKNL--LPPGRLKVLDVGCGTCEIGLLFA 70

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
           E GH V   DLS +M+ +A+  A  +G  D++ F    A+          D+++   +L 
Sbjct: 71  EMGHHVTGLDLSKKMLAKARDKASRRGF-DSV-FKKGDAEA-PPFKAGSFDVVVNRHLLW 127

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDY-----VQAGMPKKKKR 178
            +  P + +Q    VL  GG L ++    +   +               V+   P+K   
Sbjct: 128 TLPHPDTAVQNWKKVLVGGGKLIVIDGIWNDGSIETNARRFVSDFLTLLVERRNPRKGHY 187

Query: 179 T------LSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELE 232
           +      L       P ++  +   AG++ +    ++   D  RE    R       +  
Sbjct: 188 SREVDSELPNKQGVPPEKMLEYFRAAGFKNIKDIDLKDIMDLQRENMPFRKRIAYDYKYH 247

Query: 233 TRYCRQ 238
             Y  +
Sbjct: 248 LIYGEK 253


>UniRef50_Q8TNX2 Putative uncharacterized protein n=1 Tax=Methanosarcina acetivorans
           RepID=Q8TNX2_METAC
          Length = 256

 Score =  153 bits (388), Expect = 4e-36,   Method: Composition-based stats.
 Identities = 38/215 (17%), Positives = 86/215 (40%), Gaps = 18/215 (8%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
            + + A ++++        +       + L  +L +   + +RVLDAG G G  ++ +A 
Sbjct: 6   FWSNAALEYNKKTIYDFDNEKTNRAWREVLVDILGQ--KENMRVLDAGSGTGFLSMLLAT 63

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
            GH V+  + +  M+  A + A  +G+  ++ F+     ++    +   D +L   ++  
Sbjct: 64  MGHSVVGVERAPNMLKIASENAVNRGL--HVDFVLGDVYNLQMIEQDSFDALLSRYLVWT 121

Query: 125 VADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFD---YVQAGMPKKKKRT-- 179
           +  P    +    VL+PGG L ++  N +  L  +     +    ++   + + KK    
Sbjct: 122 LESPEKAFREWLRVLKPGGRLIIIDANWYPNLSRSPFLKMWRKMSWLLDFVTEGKKLRGR 181

Query: 180 ---------LSPDYPRDPAQVYLWLEEAGWQIMGK 205
                    L       P +    LE  G++++  
Sbjct: 182 GEGDVAFYNLPFSRVERPEEDVRLLELCGYRVLEI 216


>UniRef50_Q1GR70 3-demethylubiquinone-9 3-methyltransferase n=1 Tax=Sphingopyxis
           alaskensis RepID=Q1GR70_SPHAL
          Length = 272

 Score =  153 bits (387), Expect = 6e-36,   Method: Composition-based stats.
 Identities = 46/240 (19%), Positives = 81/240 (33%), Gaps = 43/240 (17%)

Query: 5   NFDDIAEKFSRNIYGTTKGQ----LRQAILWQDLD-----RVLAEMGPQKLRVLDAGGGE 55
           +F  +A  +      +        +R A + + +D                 VLD G G 
Sbjct: 13  HFGALAADWWDPRGSSAMLHRLNPVRLAYIREQIDGHWHVDARERHPLAGKHVLDVGCGA 72

Query: 56  GQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVA--------- 106
           G     +A  G +VI  D + + I  AK  A  +G++  + +      D+          
Sbjct: 73  GLLCEPLARMGAKVIGIDAAPENIAAAKDHAAGQGLA--ISYFAGELADLPNPFVSSEVE 130

Query: 107 ------------------SHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLM 148
                                +   DL+    V+E V DP   +  L + L PGG++ L 
Sbjct: 131 TLLGSADLRGVSTSLDTNGEGKGQFDLVTSMEVIEHVVDPAVFVAELAARLAPGGLMILS 190

Query: 149 FYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
             N        +V          +P+        D    P ++   LE AG +++ +TG+
Sbjct: 191 TPNRTIASKLLLVEAA--ERIGAVPRGTHDW---DRFLKPEELTKLLEGAGLEVIDRTGL 245


>UniRef50_Q67LE6 Menaquinone biosynthesis methyltransferase ubiE n=1
           Tax=Symbiobacterium thermophilum RepID=UBIE_SYMTH
          Length = 251

 Score =  153 bits (387), Expect = 6e-36,   Method: Composition-based stats.
 Identities = 43/220 (19%), Positives = 72/220 (32%), Gaps = 26/220 (11%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           FD IAE +       + GQ  +   W   + V          +LD   G G   +  A +
Sbjct: 21  FDKIAENYDAMNQVMSAGQWEK---WHR-EFVAQTHFRPGDHILDVACGTGDLTLLDAAQ 76

Query: 66  GH---QVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
                +VI  D+S  M++  ++   A    D +      A D+    +   D +     +
Sbjct: 77  VAPDGKVIGVDISEGMLEVGRRRVAASPYKDLITLQLGNAMDLP-FPDNTFDGVTMGWAM 135

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMP--------- 173
             VA     L  ++ VL+PGG    +  +        +  G F Y +  +P         
Sbjct: 136 RNVASIPRTLSEIYRVLKPGGRFICLEASK--PFSRFIRFGFFVYWKTFLPLIDWFVVKA 193

Query: 174 -------KKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKT 206
                       + S D    P Q+     EAG+      
Sbjct: 194 GRQAKVRPYTYLSRSLDNYPFPDQLEELFREAGFVETDYQ 233


>UniRef50_Q46ER7 UbiE/COQ5 methyltransferase n=4 Tax=Methanosarcina
           RepID=Q46ER7_METBF
          Length = 253

 Score =  153 bits (387), Expect = 6e-36,   Method: Composition-based stats.
 Identities = 40/214 (18%), Positives = 93/214 (43%), Gaps = 17/214 (7%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           +D+ +  +    +G     L +A  W+ + + +  +   KL VLD G G G+ ++  AE 
Sbjct: 16  WDESSATYD-TQHGHKVKSLEEADAWKSMFKKI--IPEGKLDVLDVGCGTGELSVLFAEM 72

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV 125
           GH V   DLS +M+++ +  + ++G+S  ++F+   A++     E   D+++   +L  +
Sbjct: 73  GHNVTGLDLSEKMMEKGRLKSMSQGLS--IKFLKGDAEN-PPFDEKNFDVVITRHLLWTL 129

Query: 126 ADPRSVLQTLWSVLRPGGVLSLMFY-----------NAHGLLMHNMVAGNFDYVQAGMPK 174
            +P++ ++    VLR GG   ++                   +  ++    +  +    K
Sbjct: 130 PNPKTAVKNWNRVLRDGGYAIIVDGIWDDGSLNTRVRRFISSLGILIFEQANPWKGNYSK 189

Query: 175 KKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
           +   +L         +   +L+ AG+  +    +
Sbjct: 190 ELAASLPNASGTSLEESRQYLKNAGFSKIDAYDI 223


>UniRef50_Q012C7 Dihydroxypolyprenylbenzoate methyltransferase (ISS) n=1
           Tax=Ostreococcus tauri RepID=Q012C7_OSTTA
          Length = 351

 Score =  153 bits (386), Expect = 8e-36,   Method: Composition-based stats.
 Identities = 47/217 (21%), Positives = 76/217 (35%), Gaps = 19/217 (8%)

Query: 6   FDDIAEKFSRNIYGTTKG-----QLRQAILWQDLDRVLAEM--------GPQKLRVLDAG 52
           F+  A  +     G           R A +   +     E           +  RVLD G
Sbjct: 105 FERDAALWWNETRGPFAALHAMNPTRVAFVRDAMREQFKETLGTNAMRDALRGTRVLDVG 164

Query: 53  GGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAK-GVSDNMQFIHCAAQDVASHLET 111
            G G  A  +A  G  V   D     I+ A+  A    G+   +++ H AA+ +      
Sbjct: 165 CGGGIFAESLARLGADVTAIDAGLANIEIARAHAARDPGLDGRLRYEHVAAEALGDRG-E 223

Query: 112 PVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAG 171
             D +    V+E V+DP    ++L  ++RPGG L L   N         + G  +     
Sbjct: 224 TFDAVTSLEVIEHVSDPMGFAKSLGKLVRPGGALFLSTINRTARSFAFAIVGA-ERALGL 282

Query: 172 MPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
           +P       S      P +V L    +G ++    G+
Sbjct: 283 VPPGTH---SFSKFLTPGEVALLASRSGCEMRELAGM 316


>UniRef50_Q3MEY9 Cyclopropane-fatty-acyl-phospholipid synthase n=5 Tax=Cyanobacteria
           RepID=Q3MEY9_ANAVT
          Length = 260

 Score =  153 bits (386), Expect = 8e-36,   Method: Composition-based stats.
 Identities = 43/191 (22%), Positives = 86/191 (45%), Gaps = 12/191 (6%)

Query: 14  SRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLR-VLDAGGGEGQTAIKMAERGHQVILC 72
           ++N +  T  Q + + +WQ  + +L  + PQ    +LD G G GQ   K+A+ G +V+  
Sbjct: 7   AKNFWDATLYQDKHSFVWQYGEDLLQLLNPQPGEFILDLGCGTGQLTEKIAQSGAEVLGT 66

Query: 73  DLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVL 132
           D +A MI++A+Q         ++ F    A++    ++ P+D +  +A+L WV +P + +
Sbjct: 67  DNAATMIEKARQN------YPHLHFDVADARN--FRVDKPLDAVFSNAMLHWVKEPEAAI 118

Query: 133 QTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVY 192
            ++   L+ GG     F     +     +          +     + L+P Y     +  
Sbjct: 119 ASIHQALKSGGRFVAEFGGKGNIKY---ILEALYNALETLGIHNPQALNPWYFPSIGEYV 175

Query: 193 LWLEEAGWQIM 203
             LE+ G+ + 
Sbjct: 176 NILEKQGFDVT 186


>UniRef50_D1YW16 ABC transporter ATP binding protein n=3 Tax=Methanocella paludicola
           SANAE RepID=D1YW16_METPS
          Length = 572

 Score =  153 bits (386), Expect = 8e-36,   Method: Composition-based stats.
 Identities = 49/215 (22%), Positives = 83/215 (38%), Gaps = 18/215 (8%)

Query: 1   MQD-----RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGE 55
           M D     + +D +++K+   + GT    LR       L+++  E G    R ++ G G 
Sbjct: 6   MADTGAGIKFWDAVSQKYDNAVDGTMGKNLRPT----ALEKLSQEAGL--GRAVELGCGT 59

Query: 56  GQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDL 115
           G     +A     V+  D    M+ RA +   + G   N+ F         S  +   D 
Sbjct: 60  GYFTKTLARVADSVVATDFCEGMLARAMERLSSAG---NITFQKEDCMK-TSFPDDTFDT 115

Query: 116 ILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDY-VQAGMPK 174
           +L   VL ++ DP + L     +L+PGG L ++  N     +         Y + AG   
Sbjct: 116 VLMALVLNYIPDPAAALAEARRILKPGGRLIIV--NPDNSFIGEARKRLSSYKLMAGYGD 173

Query: 175 KKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVR 209
            + R            +Y  LE AG++I     +R
Sbjct: 174 AQVRYPQTFRNLSADGLYKMLETAGFKIEASELIR 208


>UniRef50_A8TN90 Ubiquinone biosynthesis O-methyltransferase n=1 Tax=alpha
           proteobacterium BAL199 RepID=A8TN90_9PROT
          Length = 239

 Score =  153 bits (386), Expect = 8e-36,   Method: Composition-based stats.
 Identities = 51/209 (24%), Positives = 82/209 (39%), Gaps = 8/209 (3%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQL-RQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTA 59
           M DR +D        + Y   +  + R A      DR         L VLD G G G  +
Sbjct: 12  MADRWWDPDGPHGPLHRYVPARMAIIRDAARTVASDRKDQRRPMAGLSVLDIGCGGGLLS 71

Query: 60  IKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFH 119
             M   G  V   D     I  A   A   GV  ++ +   AA+D+A+      D+++  
Sbjct: 72  EPMTRLGATVTGVDADTAGIAAAVSHAA--GVGLDIAYRAGAAEDLATEG-RVFDMVVAS 128

Query: 120 AVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRT 179
            V+E VAD  +  + L +++RPGG+L L   N         +    +YV   +P+     
Sbjct: 129 EVIEHVADRDAFAEALAALVRPGGLLVLTTINRTRRSYAMAIVAA-EYVLRWVPRGTHDW 187

Query: 180 LSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
                   P ++   LE+ G+ +    G+
Sbjct: 188 ---SKFPTPDELTGLLEQRGFAVETPIGL 213


>UniRef50_B0XJ66 3-demethylubiquinone-9 3-methyltransferase n=2 Tax=Culicini
           RepID=B0XJ66_CULQU
          Length = 306

 Score =  152 bits (385), Expect = 9e-36,   Method: Composition-based stats.
 Identities = 41/185 (22%), Positives = 75/185 (40%), Gaps = 8/185 (4%)

Query: 35  DRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAE--AKGVS 92
             +      + +R+L+AG G G  A  +A  G  V+  D   +MID AK+  E  +  + 
Sbjct: 109 ADISKPDSLKGVRILEAGCGGGVLAEDLARLGAYVVGVDPGTEMIDLAKRHLETESADLK 168

Query: 93  DNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNA 152
           D +++     ++ A       D I+   V+E V +   +L+     L+PGG L +   N 
Sbjct: 169 DRLEYHAITVEEHAKKFAGTYDAIVCSEVMEHVDEKVPILEACVRCLKPGGSLFVTTENQ 228

Query: 153 HGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFH 212
             L     +    +Y+   +PK        +    P Q+   L++   +     G   F+
Sbjct: 229 TMLAWFMFIII-PEYILKFIPKGTHFY---EKFVSPGQISKILDQYQCKTKRVRGF--FY 282

Query: 213 DYLRE 217
           D +  
Sbjct: 283 DRMFN 287


>UniRef50_A4S2A7 Predicted protein n=1 Tax=Ostreococcus lucimarinus CCE9901
           RepID=A4S2A7_OSTLU
          Length = 218

 Score =  152 bits (385), Expect = 9e-36,   Method: Composition-based stats.
 Identities = 36/193 (18%), Positives = 71/193 (36%), Gaps = 7/193 (3%)

Query: 39  AEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAE-AKGVSDNMQF 97
                + L++LD G G G  A  +A  G QV   D  A  I  A+  AE    +  N+++
Sbjct: 26  PGAALRGLKILDVGCGGGILAESLARLGAQVTAIDAGAANIAIARAHAELDPDLVKNLKY 85

Query: 98  IHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLM 157
               A+++        D +    V+E V DP    +++  +++P G L +   N      
Sbjct: 86  EAVTAEELVERG-ETFDCVTSLEVIEHVTDPLEFTKSIAKLVKPKGALFVSTINRTARSF 144

Query: 158 HNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLRE 217
              +    + V   +P    +         P ++ +    A  +++   G+ V+     +
Sbjct: 145 AFAILAA-ERVLGLVPPGTHQF---SKFLTPGEIAMMAGHANCEMVELAGM-VYDPLRNK 199

Query: 218 KHQQRDCYEALLE 230
                D     + 
Sbjct: 200 WSLSSDTQINFIA 212


>UniRef50_Q465A0 Putative uncharacterized protein n=2 Tax=Methanosarcina
           RepID=Q465A0_METBF
          Length = 244

 Score =  152 bits (384), Expect = 1e-35,   Method: Composition-based stats.
 Identities = 41/232 (17%), Positives = 93/232 (40%), Gaps = 18/232 (7%)

Query: 1   MQDR---NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQ 57
           M+D+    +D  +  +        K    +  +W+ +   +  +  +K+R ++ G G G 
Sbjct: 7   MKDKILEYWDYRSSDY---HTEYAKCMDEEMEIWKSVFSEIL-LTDKKIRAVEVGTGPGL 62

Query: 58  TAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLIL 117
            AI +A  GH V   DLS  M+++A + A+ KGV  ++  +   A+ +    +   D +L
Sbjct: 63  LAISLAAMGHDVTGVDLSENMLEKAAENAKEKGV--DVSLVQGDAEKIP-LNDGEYDFVL 119

Query: 118 FHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFY----NAHGLLMHNMVAGNFDYVQAGMP 173
              +L  +  P   +     +L+ GG++ ++      N  G    +     F+ + +G+ 
Sbjct: 120 SKYLLWTLPQPDKFMSECCRLLKDGGLMMIVDGLWFQNPDGTEKKSSRYEKFNELYSGVK 179

Query: 174 KKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCY 225
                 L       P ++    +  G++ +    ++ +  +L          
Sbjct: 180 P----NLPLAKNNTPERITALAQSHGFEAVSWRFLKDYDAFLERNDPSGHEA 227


>UniRef50_A8MFN7 Methyltransferase type 11 n=1 Tax=Alkaliphilus oremlandii OhILAs
           RepID=A8MFN7_ALKOO
          Length = 266

 Score =  152 bits (384), Expect = 1e-35,   Method: Composition-based stats.
 Identities = 49/261 (18%), Positives = 110/261 (42%), Gaps = 19/261 (7%)

Query: 11  EKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVI 70
           EK+      TT     + I +     VL     +  R+L+ G G G  +    E+G+ VI
Sbjct: 9   EKYDEESRITTNNA--RKIEFLMTTGVLDNHIEKTHRILEIGAGTGAYSFYYGEKGNFVI 66

Query: 71  LCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVA---D 127
             D++ + I+   Q  + +G   N+Q     A D++       D++L    +  +    D
Sbjct: 67  ATDITPKHIEIIGQKMKERGNDINLQAEVANATDLSQFSSESFDVVLCLGPMYHLTNSSD 126

Query: 128 PRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQA---------GMPKKKKR 178
            ++ L     VL+ GG+L++ + N H  ++++++  N +++           G+ ++ ++
Sbjct: 127 RKTCLSEALRVLKKGGLLAIAYINKH-FVLNSVMIRNKEFLTRNFIDKILDTGVTREGEK 185

Query: 179 TLSPD--YPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKH--QQRDCYEALLELETR 234
                  +   P ++  ++     +I+   GV     Y ++       + YE+ L    R
Sbjct: 186 ECFWTDAFFTTPDEMASYMNCFEVEIIDHLGVDGLSPYFKDAVDGMNSEEYESWLYYNMR 245

Query: 235 YCRQEPYITLGRYIHVTARKP 255
            CR++  + +  +  +  +K 
Sbjct: 246 SCREKSILGISNHGLLLCKKK 266


>UniRef50_A6UUC3 Methyltransferase type 11 n=1 Tax=Methanococcus aeolicus Nankai-3
           RepID=A6UUC3_META3
          Length = 210

 Score =  152 bits (384), Expect = 1e-35,   Method: Composition-based stats.
 Identities = 37/144 (25%), Positives = 66/144 (45%), Gaps = 7/144 (4%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           +D+ A+K+          +  +  +   L  +L +      +VLD G G G  ++ +AE 
Sbjct: 11  WDNHAKKYDNISAHGINSEKDKRAVRSALQEILGDR----KKVLDVGCGTGFLSLILAEL 66

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV 125
           GH VI  DLS  M+ +AK+ AE  G   ++ F    A+++        D I+   +L  +
Sbjct: 67  GHDVIGVDLSEGMLSKAKKKAEENGY--DILFKLGDAENLP-FDNDSFDAIVERHILWTL 123

Query: 126 ADPRSVLQTLWSVLRPGGVLSLMF 149
            +P   +     +L+ GG L L+ 
Sbjct: 124 PNPEKAINGWTKLLKNGGKLILIE 147


>UniRef50_B1I4Q7 Methyltransferase type 11 n=1 Tax=Candidatus Desulforudis
           audaxviator MP104C RepID=B1I4Q7_DESAP
          Length = 265

 Score =  151 bits (383), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 38/193 (19%), Positives = 76/193 (39%), Gaps = 16/193 (8%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           FD +AE +    Y T  G+    +  +    +         R LD G G G+ ++ +AE+
Sbjct: 4   FDRVAEDYDA-WYETPLGRKVDQL--EMCLFMRLAAPKPGERALDGGCGTGRLSLALAEK 60

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV 125
           G  V   DLS +M++ A+    +     N+  +    +++        DL+    VLE+ 
Sbjct: 61  GLVVTGVDLSPRMLEVARNRTRS---HANITLMQADVENLP-FPSLSFDLVTAFTVLEFT 116

Query: 126 ADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYP 185
            +P + ++ LW +++PGG L +   N+            + + +       +   +    
Sbjct: 117 GNPEAAVRELWRLVKPGGRLVVGVLNSWSP---------WAWQRRRRAGTGESVFAHAQF 167

Query: 186 RDPAQVYLWLEEA 198
             P  +   L   
Sbjct: 168 FSPWSMKAVLTAN 180


>UniRef50_A9ILA7 Ubiquinone/menaquinone biosynthesis methyltransferase ubiE n=32
           Tax=Alphaproteobacteria RepID=UBIE_BART1
          Length = 260

 Score =  151 bits (383), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 33/218 (15%), Positives = 76/218 (34%), Gaps = 15/218 (6%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M D  F  +AE + +     + G     +    +   L+       +VLD  GG G  A 
Sbjct: 31  MVDSVFHSVAENYDKMNDILSLG--LHRVWKNSMVAWLSPPALSHWKVLDVAGGTGDIAF 88

Query: 61  KM---AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLIL 117
           ++   + +     + D++  M+   KQ A+  G++  + F+   A+ +    +   D   
Sbjct: 89  RILKASRQKAHATVLDINGSMLSVGKQRAQKNGLAPLIDFVEANAEHLP-FEDQSFDAYT 147

Query: 118 FHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNF---------DYV 168
               +  V      L+  + VL+PGG    + ++   +   + +   +          ++
Sbjct: 148 IAFGIRNVPHIDQALREAFRVLKPGGRFLCLEFSNVEMPWLDKIYDLWSFHAIPKLGQFI 207

Query: 169 QAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKT 206
                  +    S             +++AG+  +   
Sbjct: 208 ANDGDAYRYLVESIRKFPKQNDFAHMIKQAGFSRVSYR 245


>UniRef50_Q7VRW8 3-demethylubiquinone-9 3-methyltransferase n=2 Tax=Candidatus
           Blochmannia RepID=Q7VRW8_BLOFL
          Length = 245

 Score =  151 bits (383), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 44/205 (21%), Positives = 85/205 (41%), Gaps = 8/205 (3%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
             F+  A ++  N            I    + +        K +VLD G G G  + K+A
Sbjct: 22  NFFNTFATQWWNNTGVFKSLHHINEIRANYIIK--NSHNLFKKKVLDIGCGGGLLSEKLA 79

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
           + G +V+  D+S   +  AK  A +K ++  + +I   A++ A       DLI    +LE
Sbjct: 80  QAGAKVVGLDISPNSLIIAKAHALSKNLT--INYILETAEEHALKYIKYYDLIACMELLE 137

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPD 183
            V DP S++    S+++ GG +     N        ++ G  +Y+   +P       + +
Sbjct: 138 HVPDPLSIIHACSSMVKVGGSVFFSTLNRTMKAWLLVIIGA-EYLIHLLPIGTH---TFN 193

Query: 184 YPRDPAQVYLWLEEAGWQIMGKTGV 208
               P+++  W++    +    TG+
Sbjct: 194 KFITPSELLNWIDTTKLEANNITGI 218


>UniRef50_C7PC96 Methyltransferase type 11 n=1 Tax=Chitinophaga pinensis DSM 2588
           RepID=C7PC96_CHIPD
          Length = 252

 Score =  151 bits (382), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 40/224 (17%), Positives = 76/224 (33%), Gaps = 22/224 (9%)

Query: 16  NIYGTTKGQLRQAILWQDLDRVLAEMGPQ-KLRVLDAGGGEGQTAIKMAERGHQVILCDL 74
             +     + + + ++   + ++  + P    ++LD G G G+   ++AE G +V   D 
Sbjct: 1   MSWNAELYKEKHSFVFGYGNNLIEWLQPAAGEQILDLGCGTGELTAQVAESGAKVTGLDS 60

Query: 75  SAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQT 134
           S  MI  AK+          + F    A      L    D +  +A L W+      L  
Sbjct: 61  SPAMIASAKEHF------PQVTFQVADATS--FSLPEQFDAVFSNATLHWIRQQEKALDR 112

Query: 135 LWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLW 194
           +   L+PGG   L       +   + + G  +   A    +        Y     +    
Sbjct: 113 IHQHLKPGGRFVLEMGGKGNV---DDITGALEKAMA---DRGYTYKPFWYFPSVGEYTSL 166

Query: 195 LEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQ 238
           LEE G++I           Y   + +  D    ++E    +   
Sbjct: 167 LEEYGFRINQVL-------YFDRETELADPENGIVEWLQMFGSH 203


>UniRef50_Q2W6W0 3-demethylubiquinone-9 3-methyltransferase n=7
           Tax=Alphaproteobacteria RepID=UBIG_MAGSA
          Length = 249

 Score =  151 bits (382), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 43/210 (20%), Positives = 72/210 (34%), Gaps = 11/210 (5%)

Query: 1   MQDRNFDDIAEKFSRNIYGTT--KGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQT 58
           M +  +D    KF             +R+                + L +LD G G G  
Sbjct: 23  MAEAWWDPQ-GKFKPLHRFNPVRLAFMRRHFAAHFGRDESLMRPFEGLTLLDVGSGGGLL 81

Query: 59  AIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILF 118
           +  +A  G  V   D   + +  A+  AE  GV   + +     + +        D++L 
Sbjct: 82  SEPLARMGFAVTGIDAGDKNVAVARLHAEQTGVP--VDYRVSTPEQLD--PNEAFDVVLS 137

Query: 119 HAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKR 178
             V+E V D  + L    + L+PGGV      N         V G  +YV   +PK    
Sbjct: 138 MEVVEHVPDVSAFLGHATARLKPGGVFMGATLNRTAKAWALAVVGA-EYVLGWLPKGTHD 196

Query: 179 TLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
               +    P++    L + G  +    G+
Sbjct: 197 W---NKFVRPSEFAAMLRDRGITVRQMAGM 223


>UniRef50_B1BEI5 Probable S-adenosylmethionine-dependent methltransferase n=8
           Tax=Clostridium perfringens RepID=B1BEI5_CLOPE
          Length = 267

 Score =  151 bits (382), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 59/266 (22%), Positives = 114/266 (42%), Gaps = 20/266 (7%)

Query: 8   DIAEKFSRNIYGTTKGQLRQAILWQDLDR---VLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
           DI  ++          +L       +L     ++ E  PQ+ ++LD G G G+ +I++ +
Sbjct: 3   DIIREYYNKNSKNEWLRLNDPYNRLELFSTMYMIKEYFPQEGKILDIGSGPGRYSIELLK 62

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
           RG++V L DLS + ID AK   E+ G+  N  +I   A  +    +   D IL    +  
Sbjct: 63  RGYEVSLMDLSEKSIDMAKNNIESMGLKAN-DYICGDALYLDFIKDNTFDGILLMGPMYH 121

Query: 125 V---ADPRSVLQTLWSVLRPGGVLSLMFYN-----AHGLLMHNMVAGNFDYVQAGMPKKK 176
           V    D   +L+    +L+PGG++ + + N       GL        + + +     +K 
Sbjct: 122 VKSREDRIRILENCMRILKPGGIILIAYINSLGVLKVGLSDFPQEYKDINKIYDLFDEKG 181

Query: 177 ---KRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHD----YLRE-KHQQRDCYEAL 228
              + + +  Y   P +    + E G+ I+ + G   F      Y+ +   + ++ Y  L
Sbjct: 182 FSQEESFTETYFTVPEKAISEVNEVGFNILSRAGAESFLSGQAFYMTKYYLEDKEIYFNL 241

Query: 229 LELETRYCRQEPYITLGRYIHVTARK 254
           L++ T  C  E +     ++ + A+K
Sbjct: 242 LKVATEKCEDERFRDSTEHLIIVAKK 267


>UniRef50_D1BE92 Methylase involved in ubiquinone/menaquinone biosynthesis n=2
           Tax=Actinomycetales RepID=D1BE92_SANKS
          Length = 236

 Score =  150 bits (380), Expect = 4e-35,   Method: Composition-based stats.
 Identities = 44/259 (16%), Positives = 86/259 (33%), Gaps = 25/259 (9%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M   ++D  A+ +      +      +     DL         +   +LDAG G G  A 
Sbjct: 1   MSADDYDRFADDYEAENASSLLNAYYERPAVLDLA-----GDVRGRTILDAGCGSGPLAA 55

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
           ++  RG  V+  D S  MID A++      + + +        +   + +   D ++   
Sbjct: 56  ELVTRGADVVGFDGSPAMIDLARRR-----LGEAVPLTVHDLTEPLPYDDETFDDVVASL 110

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
           VL ++ D  + L  +  VL+PGG L     +    +++      F         +     
Sbjct: 111 VLHYLEDWDAPLAEIRRVLKPGGRLIASVNHPFAQVLNAPTEDYFATRLYDEDVELAGKP 170

Query: 181 SPDYPRDP--AQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQ 238
           +          +V   + +AG  +            + E     D    LL        +
Sbjct: 171 TVLTFWHRPLREVVRAVTDAGLSVR----------VIDEPAPSADTPADLLPPRIASGER 220

Query: 239 EPYITLGRYIHVTARKPQS 257
             +     ++ V A KP +
Sbjct: 221 SAFFC---FLFVVAEKPAA 236


>UniRef50_A9MCZ2 Ubiquinone/menaquinone biosynthesis methyltransferase ubiE n=51
           Tax=cellular organisms RepID=UBIE_BRUC2
          Length = 269

 Score =  150 bits (380), Expect = 4e-35,   Method: Composition-based stats.
 Identities = 37/226 (16%), Positives = 76/226 (33%), Gaps = 19/226 (8%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
           +  F  +A+++       + G     +    +   LA         LD  GG G  A ++
Sbjct: 42  NDVFHKVAKRYDIMNDLMSAG--MHRVWKDAMVAWLAPSKRPGWTSLDVAGGTGDIAFRI 99

Query: 63  AE---RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFH 119
            E   R   V + D++  M+   ++ A  KG+ DN++F+   A+++    +   D     
Sbjct: 100 VEVSGRQAHVTILDINGSMLGVGRERAIKKGLIDNLEFVEANAEELP-FEDNSFDAYTIA 158

Query: 120 AVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNA---------HGLLMHNMVAGNFDYVQA 170
             +  V      L   + VL+PGG    + ++          +       +      +  
Sbjct: 159 FGIRNVPHIDKALSEAYRVLKPGGRFLCLEFSEVELPVLDKVYDEWSFRAIPRIGKMITG 218

Query: 171 GMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKT----GVRVFH 212
                     S             +E+AG++ +       G+   H
Sbjct: 219 DADSYSYLVESIRKFPKQQDFAAMIEKAGFERVSYRNFTGGIAALH 264


>UniRef50_A9KR97 Methyltransferase type 11 n=1 Tax=Clostridium phytofermentans ISDg
           RepID=A9KR97_CLOPH
          Length = 265

 Score =  150 bits (380), Expect = 4e-35,   Method: Composition-based stats.
 Identities = 38/224 (16%), Positives = 88/224 (39%), Gaps = 9/224 (4%)

Query: 37  VLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQ 96
            + +   +  R+LD G G G+ ++  A +G++V   +L++  I+  ++    +   D ++
Sbjct: 45  YIEKYLKEGDRILDLGAGAGEYSLYFARKGYEVTAVELASANIEAFQKKITGE---DKIE 101

Query: 97  FIHCAAQDVASHLETPVDLILFHAVLEWV---ADPRSVLQTLWSVLRPGGVLSLMFYNAH 153
            IH  A D++   E   D++L    L  +    D +  +     VL+P G +   F    
Sbjct: 102 LIHGNALDLSCFAEDSFDVVLLFGPLYHLSKEEDRQKCITEAKRVLKPTGTIFFAFILND 161

Query: 154 GLLMHNMVAGNFDYVQAGMPKKKKRTLS-PDYPRDPAQVYLWLEEAGWQIMGKTGVRVFH 212
            +++  +      +++     +  +    P       Q    L+ AG QI+ +       
Sbjct: 162 MVILTELYYRQDFFLENSYDHETFKVEDFPFVFFTVDQTREMLQAAGIQILKEIASDGVS 221

Query: 213 DYLREK--HQQRDCYEALLELETRYCRQEPYITLGRYIHVTARK 254
           + L +K      + Y+  +      C +   +    ++    +K
Sbjct: 222 ELLEDKINAMDEESYKQYVRYHLYCCEKPEMLGRSNHLLTIGKK 265


>UniRef50_A7I8W9 Methyltransferase type 11 n=3 Tax=Methanomicrobiales
           RepID=A7I8W9_METB6
          Length = 243

 Score =  150 bits (379), Expect = 5e-35,   Method: Composition-based stats.
 Identities = 51/254 (20%), Positives = 92/254 (36%), Gaps = 23/254 (9%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
           +++D+IAE +  + Y   +G+     + + +   L    P+   +LD G G G    K  
Sbjct: 11  QHYDEIAEVYDLH-YDHPRGRTYHTRISRHVMEAL----PRGGALLDIGCGTGLFVEKYL 65

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
             G   +  DLS  MI+RA++     G      F     + +    +   D +    V  
Sbjct: 66  HHGGSAVGIDLSRNMIERARRRCSCCG------FTLGTGESLP-FRDNSFDAVASLLVFS 118

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMH-NMVAGNFDYVQAGMPKKKKRTLSP 182
           +V DP S+L   + V+RPGG +S+       L     ++    + ++  +P    +    
Sbjct: 119 YVRDPESMLNEAYRVMRPGGAISICTLGKKLLTSGIPVLYKVSEKIR--IPHVVMKDFGE 176

Query: 183 DYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPYI 242
            Y  D   +      AG+  +  +       +    H         L        +    
Sbjct: 177 HY-YDEEDMRALFSRAGFCNVKVS-------WCSFAHIDMGDPLFNLAQRMEPFIERRIP 228

Query: 243 TLGRYIHVTARKPQ 256
            L   I V A+KP 
Sbjct: 229 QLTYNICVDAQKPA 242


>UniRef50_B0C971 Methyltransferase, putative n=1 Tax=Acaryochloris marina MBIC11017
           RepID=B0C971_ACAM1
          Length = 284

 Score =  149 bits (378), Expect = 5e-35,   Method: Composition-based stats.
 Identities = 39/207 (18%), Positives = 78/207 (37%), Gaps = 15/207 (7%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
           D+    +A+ + R      +GQ    I  + L+            VLD G G G  AI  
Sbjct: 7   DKFKQGVADFYDRRSRSYDQGQWHPQICDRLLEYARI---GAGQTVLDIGTGTGYLAIAS 63

Query: 63  AERGH---QVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFH 119
           A+R      V   D+S  M+ +A++  +  G+S N+      A+ +  +     D+IL  
Sbjct: 64  AQRVGDQGHVTGVDISPGMLQQAQRKIQRLGLS-NVVVQRADAEAL-DYPSHHFDVILCA 121

Query: 120 AVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRT 179
               W+ D  + L+  + +L+P G +++        +   ++          + +     
Sbjct: 122 HTFPWMTDKAATLRLWYQLLKPRGRIAVHTPADTAYIGAVVLR-------RVLAEYGLEL 174

Query: 180 LSPDYPRDPAQVYLWLEEAGWQIMGKT 206
              +      Q     E+AG++ +   
Sbjct: 175 EPSNRLGSIEQCRQLFEKAGFEAVEIY 201


>UniRef50_C1E266 Predicted protein (Fragment) n=6 Tax=cellular organisms
           RepID=C1E266_9CHLO
          Length = 252

 Score =  149 bits (377), Expect = 7e-35,   Method: Composition-based stats.
 Identities = 46/235 (19%), Positives = 79/235 (33%), Gaps = 18/235 (7%)

Query: 6   FDDIAEKFSRNIYG----------TTKGQLRQAILWQDLDRVLAEMGP-QKLRVLDAGGG 54
           F+  A  +     G          T  G +R+A+       +    GP   LR+LD G G
Sbjct: 5   FEADAALWWDEERGPFAPLHAMNPTRVGFIREALARHFDGGIEPGTGPLAGLRILDVGCG 64

Query: 55  EGQTAIKMAERGHQVILCDLSAQMIDRAKQAAE-AKGVSDNMQFIHCAAQDVASHLETPV 113
            G     +A  G  V   D +   I  A   A    G+S  + + H    +  +      
Sbjct: 65  GGILCESLARLGADVTGIDAAKGNIAIATAHAAKDPGMSRRVTY-HATTAEEVAAAGAKF 123

Query: 114 DLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMP 173
           D ++   V+E V DP   ++ L ++  PGG + +   N         +    + V   +P
Sbjct: 124 DAVVSLEVVEHVNDPEGFVRQLEALTNPGGAVFMSTVNRTARSYALAIVAA-ERVLRWVP 182

Query: 174 KKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEAL 228
                    D    P ++      AG ++    G+ V+   L    +        
Sbjct: 183 PGTHEF---DKFMTPEELAAVAHRAGLEVREAAGM-VYTPPLPAPGRNGAVAGRW 233


>UniRef50_Q8TJW5 Putative uncharacterized protein n=1 Tax=Methanosarcina acetivorans
           RepID=Q8TJW5_METAC
          Length = 306

 Score =  149 bits (377), Expect = 9e-35,   Method: Composition-based stats.
 Identities = 59/260 (22%), Positives = 103/260 (39%), Gaps = 18/260 (6%)

Query: 11  EKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVI 70
             +  N     +      I ++   R L    P+K R+LD GGG G+ +I +A +GH V 
Sbjct: 44  AFYDGNPEYEWRRLEIHRIEYETTRRYLDIYLPKKSRILDVGGGPGRYSIYLASQGHNVT 103

Query: 71  LCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRS 130
           L DLS++ I  AK  AE +GV     FIH  A ++  H +   D IL       + D   
Sbjct: 104 LFDLSSKNILLAKAKAEEQGVHLE-GFIHGNALELDHHTKGRFDAILCMGPSYHLTDESQ 162

Query: 131 ---VLQTLWSVLRPGGVLSLMFYNAHGLLMH------NMVAGNFDYVQAGMPKKK----- 176
              V+    +VL+PGG+L + F +A   ++       +M+    D +   +         
Sbjct: 163 RHIVIDKCVNVLKPGGILFVSFISAFAPIIDMMKGYPHMILDEKDRLLDYLKDGTNIVSE 222

Query: 177 -KRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREK--HQQRDCYEALLELET 233
                +  +  +PA +   +++   + +  T +         K      DC+ A +EL  
Sbjct: 223 ENPGFTDAWFENPANIEGIMKKYPLEKLVITAIEGMLSPNEGKINSLPEDCFNAFIELSM 282

Query: 234 RYCRQEPYITLGRYIHVTAR 253
           +            ++    R
Sbjct: 283 KLSTNPMTWGSCEHMLYIGR 302


>UniRef50_B9XIN5 Ubiquinone/menaquinone biosynthesis methyltransferase n=1
           Tax=bacterium Ellin514 RepID=B9XIN5_9BACT
          Length = 263

 Score =  148 bits (375), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 36/172 (20%), Positives = 69/172 (40%), Gaps = 7/172 (4%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           F  IA  +       + G        Q L  +    G    R LD   G G     +A  
Sbjct: 43  FATIAPHYDLINDLQSFG--LHRFWKQRLLNL--AHGRPGERALDLCCGTGDVTFALAAT 98

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV 125
           G + +  D S  M+  A+Q  +++    +++F++  AQ++    +   D++     L  +
Sbjct: 99  GMEAVGLDFSEPMLKVARQRTQSQNPKPSVRFLNGDAQNIP-FPDGSFDVVTISYGLRNL 157

Query: 126 ADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKK 177
           AD    L+ +  V +PGG L ++ +      +   +   F Y++  +P   K
Sbjct: 158 ADLDLGLREMKRVAKPGGRLLVLDFGKPDNAVWRSLY--FTYLKFFVPVMGK 207


>UniRef50_Q5GT88 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-benzoquinol methylase
           n=9 Tax=Wolbachia RepID=Q5GT88_WOLTR
          Length = 402

 Score =  148 bits (375), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 35/172 (20%), Positives = 75/172 (43%), Gaps = 8/172 (4%)

Query: 38  LAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQF 97
           L +   +KL +LD G G G  +  +A  G  V+  D+  + I  A+  A+  G+  N+++
Sbjct: 213 LKKCDLKKLSLLDVGCGGGILSESIARVGINVLGIDVCEENIKVAQSHAKKVGL--NIEY 270

Query: 98  IHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLM 157
            H + ++++       D++L   V+E V +    ++    +L+P G++ +   N      
Sbjct: 271 THTSIEELS--NNQKYDVVLLMEVVEHVDNLELFIKKAIELLKPEGLIFISTINRTFKSF 328

Query: 158 HNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVR 209
              + G  +Y+   +PK        +    P+++   L E    +    G+ 
Sbjct: 329 FLAIIGA-EYILNWLPKGTHNW---NKFLKPSEIANHLREGNVTLQDMAGME 376


>UniRef50_C7MMN1 Methylase involved in ubiquinone/menaquinone biosynthesis n=1
           Tax=Cryptobacterium curtum DSM 15641 RepID=C7MMN1_CRYCD
          Length = 263

 Score =  148 bits (375), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 39/165 (23%), Positives = 65/165 (39%), Gaps = 6/165 (3%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
           D  +D+ +  +S  I      ++     W  L   +   G + LRVLD G G G  +I  
Sbjct: 12  DAYWDERSSSYSETIQRELTTEIYHH-WWSVLADTIPGFGKRSLRVLDIGCGPGFFSILC 70

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSD----NMQFIHCAAQDVASHLETPVDLILF 118
           A+ G  V   D S +M+  A+Q     G++      ++F    A+ +    +   D+I+ 
Sbjct: 71  AQAGCSVDALDCSVKMLAHARQNLFHAGLNTADNVQVRFHQGDARFLP-FDDGVFDVIVT 129

Query: 119 HAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAG 163
             V   + DP    +    VL PGG L       +  L    +  
Sbjct: 130 RNVTWNLEDPLGAYREWQRVLIPGGRLINFDAGWYSYLSDVGIEA 174


>UniRef50_D1JD56 Putative uncharacterized protein n=1 Tax=uncultured archaeon
           RepID=D1JD56_9ARCH
          Length = 267

 Score =  148 bits (375), Expect = 2e-34,   Method: Composition-based stats.
 Identities = 45/233 (19%), Positives = 92/233 (39%), Gaps = 22/233 (9%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
           +  + D  E++         G   +    +    +  E+   KL +LDAG G G  A+ +
Sbjct: 18  NDYWKDAGEEYDNYP-----GFDTEEEKEEWKKFLSDEIVGNKLSILDAGTGTGFLALSL 72

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
           A  GH V+  DLS  M+ RA + A+ +G+  N+       + +    +   D+++   VL
Sbjct: 73  AGMGHDVVGIDLSEGMLSRAIKKAKERGL--NLDLRMGDVESL-DFDDKSFDVVVTRWVL 129

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLM---FYNAHGLLMH----------NMVAGNFDYVQ 169
             +  P   ++    VL+PGG +           G               ++     + +
Sbjct: 130 WTLIHPDKAIEEWLRVLKPGGYVYAFGSKEPGRKGRWRWFKANFAMAAITVLERRNAWAR 189

Query: 170 AGMPKKKKRTLSPDYPRD-PAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQ 221
           +   K+ K  L   Y +  P +     ++AG   +    ++  ++  +EK ++
Sbjct: 190 SDYDKEVKENLPLHYDKTGPREKVKLFKKAGLNDVYVLDLKEVNNIHKEKSKE 242


>UniRef50_D0LMD2 Methyltransferase type 11 n=1 Tax=Haliangium ochraceum DSM 14365
           RepID=D0LMD2_HALO1
          Length = 415

 Score =  148 bits (374), Expect = 2e-34,   Method: Composition-based stats.
 Identities = 41/211 (19%), Positives = 74/211 (35%), Gaps = 18/211 (8%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEG---QT 58
             R FD IA  +   +        ++ +    L             VL+ G G G     
Sbjct: 11  TKRWFDAIASVYDEGLSALLLSLHQKMLEQARLQT--------GETVLNLGCGTGMDSFL 62

Query: 59  AIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILF 118
              +      V+  D++ +M+  A + A ++G+ DN+ F    A+ +        D I+ 
Sbjct: 63  TAPLIGEEGSVVGIDIAPEMVRLANEKAGSRGL-DNVTFQVMDAEKL-KFKANHFDAIIS 120

Query: 119 HAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMP--KKK 176
              L +  + R  L+  + VL+PGG  +L            MV   F  V   +P     
Sbjct: 121 QWALMFFPNDRGALREAYRVLKPGGRFALSVVGRPENSPFLMVP--FRVVAKTLPGVAIS 178

Query: 177 KRTLSPDYPRDPAQVYLWLEEAGWQIMGKTG 207
           +             +   L +AG+ +   +G
Sbjct: 179 EGGPPTFRFAREGALEAALSQAGF-VSTWSG 208


>UniRef50_A6WCY9 Methyltransferase type 12 n=2 Tax=Actinomycetales
           RepID=A6WCY9_KINRD
          Length = 265

 Score =  148 bits (374), Expect = 2e-34,   Method: Composition-based stats.
 Identities = 59/234 (25%), Positives = 99/234 (42%), Gaps = 4/234 (1%)

Query: 11  EKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVI 70
           E+ ++         +    + + L    A  G  +L V+D GGG G  A+++A  GH+V+
Sbjct: 17  ERVAKERGRPRTSTVLWEGVQRLLADAAAAPGAGELTVVDLGGGTGGLAVRVAALGHRVV 76

Query: 71  LCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVAS-HLETPVDLILFHAVLEWVADPR 129
           + D S   +   ++     G+SD ++ +   A D+A+       D++L H VLE V DPR
Sbjct: 77  VVDPSPDALAALERRTVEAGLSDRVRALQGDATDLAAVLEPGRADVLLCHGVLEVVDDPR 136

Query: 130 SVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPD---YPR 186
           + L+     LRPGG LSL+       ++  +++G+ D     +     R    D      
Sbjct: 137 AALRAAHDALRPGGRLSLLVAQWPASVLARVLSGHLDQALHVLSDADHRWSGHDPLRRRF 196

Query: 187 DPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP 240
           D A      + AG+ +    G R F D +     + D    LL          P
Sbjct: 197 DRASATALAQGAGFTVTAVEGTRTFSDVVPSTRTESDADVELLRRLEALASTSP 250


>UniRef50_B0MSN4 Putative uncharacterized protein n=1 Tax=Alistipes putredinis DSM
           17216 RepID=B0MSN4_9BACT
          Length = 238

 Score =  148 bits (374), Expect = 2e-34,   Method: Composition-based stats.
 Identities = 46/212 (21%), Positives = 84/212 (39%), Gaps = 16/212 (7%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           FD IA  + R  +  +    +   LW+     +     Q  R+LD   G G  A+ MA R
Sbjct: 18  FDRIAPAYDRLNHTLSF---QIDKLWRRHVVRIVRRM-QPRRILDVATGTGDLALAMARR 73

Query: 66  --GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
             G QV+  DLS  M+  A++ A A G+ + +      A+ +    +  VD++     + 
Sbjct: 74  MRGVQVLGVDLSENMLAEARRKATACGLDERVVLSLGDAERL-EVADASVDVVTVAFGVR 132

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDY---------VQAGMPK 174
              D  + L+ +  VL+PGG + ++ ++     +   V G + +         +      
Sbjct: 133 NFGDLGAGLREIVRVLKPGGKVVILEFSTPRNPLFRRVYGLYSHRLLPAIGGMISKDRKA 192

Query: 175 KKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKT 206
            +    S D    P      + EAG++     
Sbjct: 193 YEYLPASVDEFPAPECFMAMMREAGFKDCRAR 224


>UniRef50_A6TPQ5 Methyltransferase type 11 n=1 Tax=Alkaliphilus metalliredigens QYMF
           RepID=A6TPQ5_ALKMQ
          Length = 251

 Score =  148 bits (373), Expect = 2e-34,   Method: Composition-based stats.
 Identities = 38/195 (19%), Positives = 78/195 (40%), Gaps = 8/195 (4%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
           +  ++  A  FS ++    +   +    W  L +    M  +KL+VLD G G G  A+ +
Sbjct: 8   EDYWNQRARGFSLSVVEELEDDKKDQ--WLQLFKKYG-MTERKLKVLDVGTGSGFFAVLL 64

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
           A+ GH V   D +  M+  A++ A    V   +      AQ++    +   DLI+   ++
Sbjct: 65  AQEGHDVTGIDYTPNMLKHAEETARKFNV--KLDLRQMDAQNL-EFEDESFDLIVTRNLM 121

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSP 182
             +  P    +    VL+ GG +     N +  L  ++    ++ ++    ++     + 
Sbjct: 122 WNLEFPEKAYREWIRVLKKGGKIINFDGNYYLHLHDDVYKEGYEKIEYVPDRQGHTKNNI 181

Query: 183 DY--PRDPAQVYLWL 195
           D        ++   L
Sbjct: 182 DNVDFSIMREIAREL 196


>UniRef50_UPI0001B4EB31 methyltransferase n=1 Tax=Streptomyces sp. C RepID=UPI0001B4EB31
          Length = 262

 Score =  148 bits (373), Expect = 2e-34,   Method: Composition-based stats.
 Identities = 66/256 (25%), Positives = 121/256 (47%), Gaps = 11/256 (4%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           FD +   ++ +   + +G+LR  ++ +   R+LAE+     R+LD G G G+  +++A  
Sbjct: 7   FDSVGAAYAAH-SDSARGRLRHDLVER---RLLAELPAAPARILDVGCGNGEMTLRLAAA 62

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKG-VSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
           G++V   D +A M+  A     A+  ++D +Q ++     ++     P D +  H VL +
Sbjct: 63  GYRVTGVDPAATMLAAAADRLAARPELADRVQLVNAGLDSLS-LDGKPFDGVCCHGVLMY 121

Query: 125 VADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLS--- 181
           + DP   +  L  ++ PGG+LS++  N+  + +   +AG+ +     +  +  R++    
Sbjct: 122 LDDPGEAVVRLAGLVAPGGLLSILAKNSRAVGVREALAGDSETACRLIVSQADRSVGNLG 181

Query: 182 -PDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREK-HQQRDCYEALLELETRYCRQE 239
                 DP  +     E G       GVR+FHD+  +        Y A LELE     + 
Sbjct: 182 RETRGDDPDALDRLAAEHGLSPQPWQGVRIFHDHFDDTWAPDPAAYAAALELEWAASSRS 241

Query: 240 PYITLGRYIHVTARKP 255
           PY  LG  +H  AR+P
Sbjct: 242 PYRDLGHLVHTLARRP 257


>UniRef50_A8J700 C5-O-methyltransferase n=4 Tax=Streptomyces RepID=A8J700_9ACTO
          Length = 284

 Score =  148 bits (373), Expect = 2e-34,   Method: Composition-based stats.
 Identities = 43/226 (19%), Positives = 83/226 (36%), Gaps = 21/226 (9%)

Query: 13  FSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE-RGHQVIL 71
           +     G+T GQ    +    + ++    G    RVLD G G G+ A+++A      ++ 
Sbjct: 39  WPHPDDGSTLGQASDRLTDHMIGKLREHTGRPVRRVLDVGCGSGRPALRLAHSEPVDIVG 98

Query: 72  CDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSV 131
             +S + ++ A   AE  G+++ ++F    A D+    +   D +     L  + DP  V
Sbjct: 99  ITISPRQVELATALAERSGLANRVRFECADAMDLP-FPDASFDAVWALECLLHMPDPARV 157

Query: 132 LQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQV 191
            Q +  VLRPGG L+ M      + +        D+  + +                   
Sbjct: 158 FQEMARVLRPGGRLAAMD-----VTLRASQPTGADWSSSELAVPS--------LIPITAY 204

Query: 192 YLWLEEAGWQIMGKTGVR------VFHDYLREKHQQRDCYEALLEL 231
              + +AG ++   T +        +     +       Y   LE+
Sbjct: 205 AGMISDAGLRLTELTDIGEHVIAPSYSAMGDDVRANAHAYAEALEM 250


>UniRef50_Q2JD64 Methyltransferase type 11 n=2 Tax=Frankia RepID=Q2JD64_FRASC
          Length = 270

 Score =  148 bits (373), Expect = 3e-34,   Method: Composition-based stats.
 Identities = 63/207 (30%), Positives = 97/207 (46%), Gaps = 3/207 (1%)

Query: 48  VLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVAS 107
           ++DAGGG G  A+ +A  G+ VI+ D S   +   ++ A+ +GV+D +        D+  
Sbjct: 46  IVDAGGGSGGFAVPLAVEGYLVIVVDPSPDALAALRRRADERGVADRVTAEQGDLADLTG 105

Query: 108 H-LETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFD 166
                  DL+L H+VL+ V DP + L     VLRPGGVLSL+       ++   +AG F+
Sbjct: 106 IVGAETADLLLCHSVLDVVDDPEAALAGALRVLRPGGVLSLVVAGRAATVLARALAGRFE 165

Query: 167 YVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYE 226
             QA +  +             A++   +  AG  ++   GVRVF D +       D + 
Sbjct: 166 QAQAVLTGQGAGAPRTPAGFTTAEIVALVNAAGADVVDVHGVRVFADLVPGARVDSDPFT 225

Query: 227 A--LLELETRYCRQEPYITLGRYIHVT 251
           A  LL LE      EP+  L   +HV 
Sbjct: 226 AQRLLRLELAAAALEPFRDLAAQLHVL 252


>UniRef50_Q2RJ99 UbiE/COQ5 methyltransferase n=1 Tax=Moorella thermoacetica ATCC
           39073 RepID=Q2RJ99_MOOTA
          Length = 230

 Score =  148 bits (373), Expect = 3e-34,   Method: Composition-based stats.
 Identities = 42/195 (21%), Positives = 82/195 (42%), Gaps = 15/195 (7%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M +  FD  A  +    Y    G L   +  + +   L         +LD G G G  ++
Sbjct: 1   MAE-IFDRKAGDYDD-WYTRPLGALVDRVEKEPIYAYLDPH--AGEHILDVGCGTGNFSL 56

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
           ++A RG +V   D+S  M+ +A++ A   G++  ++F+H  A ++    +   D I+   
Sbjct: 57  ELARRGVKVTGIDISDPMLAKARKKAADAGLA--IEFLHADAMNLP-FGDNTFDKIVSVT 113

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
            LE+  D ++VL+  + VL+PGG + +     + L        +++   A  P    R  
Sbjct: 114 ALEFAPDLKAVLEESYRVLKPGGRMVIGLIGGNSLWSR-----HYEARAAREPDCLFRY- 167

Query: 181 SPDYPRDPAQVYLWL 195
                    ++   +
Sbjct: 168 --ARFYTLDELLAAM 180


>UniRef50_A5ZYR5 Putative uncharacterized protein (Fragment) n=1 Tax=Ruminococcus
           obeum ATCC 29174 RepID=A5ZYR5_9FIRM
          Length = 796

 Score =  147 bits (372), Expect = 3e-34,   Method: Composition-based stats.
 Identities = 42/197 (21%), Positives = 81/197 (41%), Gaps = 24/197 (12%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGP--QKLRVLDAGGGEGQTAIK 61
             ++  ++ F        + +L  A+  + +  + A++    +KLR+LD G G G   I 
Sbjct: 586 NYWEKRSDSF----LEQRRAELHSAMADRWMKEIQAQLPDDNKKLRILDVGCGAGFFTIL 641

Query: 62  MAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
           +A+ GHQV   DL+  MI  A+  A+ +G   + +F    A++     +   D+I+   +
Sbjct: 642 LAKAGHQVTGIDLTPDMIKNARILAQEEG--ADCEFTVMDAEN-PEFPDDTFDVIISRNL 698

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLS-------LMFY--------NAHGLLMHNMVAGNFD 166
              +   R   Q    VLR GGVL        +  +        N    ++ N +    +
Sbjct: 699 TWTLPHVRHAYQEWLRVLRKGGVLLNFDANYGITDFSNVEDLPENHAHNMLGNEMMRECE 758

Query: 167 YVQAGMPKKKKRTLSPD 183
            ++  +P       + D
Sbjct: 759 EIKRQLPISSYSRPAWD 775



 Score =  142 bits (359), Expect = 9e-33,   Method: Composition-based stats.
 Identities = 43/178 (24%), Positives = 75/178 (42%), Gaps = 16/178 (8%)

Query: 1   MQD------RNFDDIAEKFSRNIYGTTKGQLRQAILWQD-----LDRVLAEMGPQKLRVL 49
           M D        + + A  +S   Y   +    +  +W+D     L     E  P ++++L
Sbjct: 1   MSDLKNEIHDYWTNRARGYSE--YNQQEMADARRTMWRDKLLSLLGEAFPEREPGEIKIL 58

Query: 50  DAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHL 109
           D G G G  AI +AE G+QV   D + +M+  A+Q A   G+++ + +    AQ +    
Sbjct: 59  DVGTGPGFFAILLAEAGYQVTAVDYTEEMLREAQQNAG--GLAECIVWKTGDAQALDVES 116

Query: 110 ETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDY 167
               D I+   V   +  P    +    VL+PGGVL     + +G L +      ++ 
Sbjct: 117 -NSFDAIVTRNVTWNLPRPDLAYKEWLRVLKPGGVLYNFDADWYGHLYNEEKRSGYEK 173


>UniRef50_Q8NMH1 SAM-dependent methyltransferases n=2 Tax=Corynebacterium glutamicum
           RepID=Q8NMH1_CORGL
          Length = 251

 Score =  147 bits (372), Expect = 3e-34,   Method: Composition-based stats.
 Identities = 45/219 (20%), Positives = 86/219 (39%), Gaps = 9/219 (4%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
           +  +   AE +  N   + + Q  + I  +   + L  +  + ++VLD G G G     +
Sbjct: 11  NNYWSGRAEAYHLNQTQSERAQFERPIWEKVWSKALPIVSEEAVKVLDLGCGAGYVTHLL 70

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQ--FIHCAAQDVASHLETPVDLILFHA 120
           ++ G++ I  D S +MI++A Q    +  +      F    A D     E   D I    
Sbjct: 71  SDCGYETIGVDGSEEMINQATQENGLRRSTGRATAIFQVGDAHD-PEFREGSFDAITSRY 129

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMH-----NMVAGNFDYVQAGMPKK 175
           VL  + DP++ +    S+L+PGGV++ +    +   +      + V G   +V+   P +
Sbjct: 130 VLWTLLDPQAAINRWVSLLKPGGVIACVDAAWYPKGIDAGTEVDSVDGPSAFVETYTP-E 188

Query: 176 KKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDY 214
             R L                 AG + +  T +    + 
Sbjct: 189 LLRNLPMSTTSTGHNFAELFHNAGLKEVTLTPIEGLAEL 227


>UniRef50_Q17BU7 Hexaprenyldihydroxybenzoate methyltransferase n=3 Tax=Culicidae
           RepID=Q17BU7_AEDAE
          Length = 293

 Score =  147 bits (372), Expect = 3e-34,   Method: Composition-based stats.
 Identities = 32/175 (18%), Positives = 69/175 (39%), Gaps = 5/175 (2%)

Query: 35  DRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAE-AKGVSD 93
           +++ +    + + +L+ G G G     +A     V+  D   ++I+ A++  E  + +S 
Sbjct: 94  EQIQSPQVLKGVNILEVGCGGGILTEALARIHANVVGIDPGEKLINVAREHKERDQKISP 153

Query: 94  NMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAH 153
            +Q++    ++ A       D ++   VLE V D  + L+     LRPGG + +   N  
Sbjct: 154 RIQYLVETVEEHAQKNVERYDAVIASEVLEHVNDKPAFLEHCIMALRPGGSIFITTLNQT 213

Query: 154 GLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
                  +    +Y+   +P+        D    P  +   L+      +   G+
Sbjct: 214 TASWVGGIVAA-EYILKLVPENTHDW---DKFIAPLDLERILKSFNCTTVLVHGM 264


>UniRef50_D0RTX5 S-adenosylmethionine-dependent methyltransferase n=4
           Tax=Streptococcus RepID=D0RTX5_9STRE
          Length = 234

 Score =  147 bits (371), Expect = 4e-34,   Method: Composition-based stats.
 Identities = 53/244 (21%), Positives = 105/244 (43%), Gaps = 17/244 (6%)

Query: 14  SRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCD 73
            +N      G++   IL+  L  V      + ++VLD G G G  A  +AE+ +QV   +
Sbjct: 6   YKNHLEEPWGKIYYDILFDQLKNV------EGMKVLDFGSGFGIVANHLAEK-NQVTALE 58

Query: 74  LSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQ 133
            + +MI   ++       +++ + +  + + +    +   DLI+ H VLE++ D    L 
Sbjct: 59  PNMEMIIH-RKR------TNSYEQLQGSLEVLEIFKDESFDLIICHNVLEYIEDIDPYLM 111

Query: 134 TLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDP-AQVY 192
               +L+ GG LS++ +N  G +MH ++  N       +    K  L+    +    ++ 
Sbjct: 112 AFSRLLKKGGKLSIVKHNYVGRIMHTVIFENDIKKARELLLG-KDYLTHSMGQAVYYEIA 170

Query: 193 LWLEEAGWQIMGKTGVRVFHDYLREKH-QQRDCYEALLELETRYCRQEPYITLGRYIHVT 251
             ++   ++I+   G+R+F+              E +LE+E     Q PY  +  + H  
Sbjct: 171 DVIKPYPFEILDFQGIRIFYGLQPNDVKTDPGWRENMLEMELSVNNQSPYRDIAAFQHYW 230

Query: 252 ARKP 255
             K 
Sbjct: 231 LVKK 234


>UniRef50_Q8TPQ8 UbiE/COQ5 methyltransferase n=1 Tax=Methanosarcina acetivorans
           RepID=Q8TPQ8_METAC
          Length = 208

 Score =  147 bits (371), Expect = 4e-34,   Method: Composition-based stats.
 Identities = 42/204 (20%), Positives = 84/204 (41%), Gaps = 17/204 (8%)

Query: 4   RNFDDIAEK-FSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
           R + D AE  +          +  + +  + + ++L     Q+L++LD G G G  A+ +
Sbjct: 8   RAWWDTAEHDYDAIAAHGVHSEEERELWTEVITQLLG--SDQQLKILDMGTGTGFLALLL 65

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
           AE G++V   D +A  +++AK+  E  G  + + F+   A++++       D ++   ++
Sbjct: 66  AELGYEVTGADWAASKLEKAKKKMERTG--NFVNFVVEDAENLS-FESEQFDAVVSRHLV 122

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSP 182
             +A+P S  +    V +PGG +     + H    H       + +   +P         
Sbjct: 123 WTLANPDSAFKEWARVTKPGGKVLTDIPSRHS---HPGNHHFGEEIGKELPFY------- 172

Query: 183 DYPRDPAQVYLWLEEAGWQIMGKT 206
               DP  V    E AG   +   
Sbjct: 173 -NGADPGDVISMFEAAGLVNVSVR 195


>UniRef50_Q9ALM7 Methyltransferase-like protein n=2 Tax=Saccharopolyspora
           RepID=Q9ALM7_9PSEU
          Length = 275

 Score =  147 bits (371), Expect = 4e-34,   Method: Composition-based stats.
 Identities = 54/251 (21%), Positives = 89/251 (35%), Gaps = 27/251 (10%)

Query: 18  YGTTKGQLRQAILWQDLDRVLAE--MGPQKLRVLDAGGGEGQTAIKMAERGH-QVILCDL 74
           Y    G+         L  ++AE  +    +R+LD G G GQ A+++A     Q+    +
Sbjct: 37  YWENDGRASWQQAADRLTDLVAERTVLDGGVRLLDVGCGTGQPALRVARDNAIQITGITV 96

Query: 75  SAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQT 134
           S   +  A   A  +G+S  + F    A  +  + +   D       L  +++P   ++ 
Sbjct: 97  SQVQVAIAADCARERGLSHRVDFSCVDAMSLP-YPDNAFDAAWAMQSLLEMSEPDRAIRE 155

Query: 135 LWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLW 194
           +  VL+PGG+L +                       GMP    R  +        Q+   
Sbjct: 156 ILRVLKPGGILGVTEVVK-------------REAGGGMPVSGDRWPTGLRICLAEQLLES 202

Query: 195 LEEAGWQIMGKTGV----RVFHDYLREKHQQRDCYE------ALLELETRYCRQEPYITL 244
           L  AG++I+    V    R F     E+              A+       C  E Y   
Sbjct: 203 LRAAGFEILDWEDVSSRTRYFMPQFAEELAAHQHGIADRYGPAVAGWAAAVCDYEKYAHD 262

Query: 245 GRYIHVTARKP 255
             Y  +TARKP
Sbjct: 263 MGYAILTARKP 273


>UniRef50_D2UX54 Predicted protein (Fragment) n=1 Tax=Naegleria gruberi
           RepID=D2UX54_NAEGR
          Length = 252

 Score =  147 bits (371), Expect = 4e-34,   Method: Composition-based stats.
 Identities = 38/187 (20%), Positives = 77/187 (41%), Gaps = 9/187 (4%)

Query: 40  EMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIH 99
               + L +LD G G G  +  +A  G  V   D S   I+ A+    +     N+ +IH
Sbjct: 61  HEPLKGLNILDVGCGGGLVSECLARLGANVTGLDASLDNINIARTHNTSLN---NLNYIH 117

Query: 100 CAAQDVASHLETP-VDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMH 158
              +++  + E+   D I+   V+E VA  +S +  L  +L+P G L L   N       
Sbjct: 118 STVENLLYNNESTKFDCIVSVEVIEHVAHAQSFVHNLSKLLKPNGFLILSTMNRTPKSYL 177

Query: 159 NMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREK 218
             +    +YV   +P+             P ++ +++ +A  ++    G+  ++  L + 
Sbjct: 178 YTIVMA-EYVLNLVPRGTHEW---RKYVTPQEMVIFMNQANVKLYDVQGME-YNPLLNKA 232

Query: 219 HQQRDCY 225
             +++  
Sbjct: 233 FIEKNTE 239


>UniRef50_Q46F92 Putative uncharacterized protein n=2 Tax=Methanosarcina
           RepID=Q46F92_METBF
          Length = 249

 Score =  147 bits (371), Expect = 4e-34,   Method: Composition-based stats.
 Identities = 37/167 (22%), Positives = 69/167 (41%), Gaps = 10/167 (5%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLR--VLDAGGGEGQTAI 60
              ++  A+ +S  I     G  R+A        ++ E  P K R  +LD G G G   I
Sbjct: 8   KNYWEGEAQGYSEAIEDELNGFERKAW-----SDLVLEYAPSKDRLDILDIGTGPGFFPI 62

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
            +++ GH V   DL+  MI+ A+     +G S  +  +    Q++    +   DL++   
Sbjct: 63  VLSQGGHNVTGIDLTENMIEFARLNLAREGASAKL--VTMDCQNL-KFPDNCFDLLVCRN 119

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDY 167
           +   + DP    +    VL+PGG + +     +  L    +   ++ 
Sbjct: 120 LTWTLDDPAKAYKEWHRVLKPGGRVLIFDACWYLHLFDENMKIAYEK 166


>UniRef50_B0A8V1 Putative uncharacterized protein n=1 Tax=Clostridium bartlettii DSM
           16795 RepID=B0A8V1_9CLOT
          Length = 255

 Score =  146 bits (370), Expect = 6e-34,   Method: Composition-based stats.
 Identities = 44/222 (19%), Positives = 92/222 (41%), Gaps = 23/222 (10%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEM--GPQKLRVLDAGGGEGQTA 59
            +R + D AE + +      +    + + W D+ +  A +  G ++L+VLD G G G  +
Sbjct: 10  NERYWADRAEGYCQVNIDELRSN--KKLEWIDIIKSNAPVFAGDRRLKVLDIGCGPGFFS 67

Query: 60  IKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFH 119
           I ++  G+ V   D + +M+++AKQ A    + D ++F    A ++    E   DLI+  
Sbjct: 68  IILSCAGYDVTAVDYTEEMLNKAKQNAGD--LKDKIKFRRMDAHNL-EFDEGQFDLIVTR 124

Query: 120 AVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKK--- 176
            +   + DP    ++ + VLR GG +     N +  L        ++  +  +       
Sbjct: 125 NLTWNLKDPEKAYKSWYKVLRKGGKMINFDANWYLHLFDEEKRREYESDRKNVELSGMED 184

Query: 177 -------------KRTLSPDYPRDPAQVYLWLEEAGWQIMGK 205
                         R +     + P+   + L++ G++ +  
Sbjct: 185 HYTCTDIDSMEDLARQVPLSKIKRPSWDRVVLDKIGFKNIKI 226


>UniRef50_C9L9K1 SmtA protein n=1 Tax=Blautia hansenii DSM 20583 RepID=C9L9K1_RUMHA
          Length = 260

 Score =  146 bits (369), Expect = 6e-34,   Method: Composition-based stats.
 Identities = 42/219 (19%), Positives = 81/219 (36%), Gaps = 19/219 (8%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
           +  +   A  ++  I              + +          K+++LD G G G  +I +
Sbjct: 16  EAYWTRRASSYTDVIKKNLADGWEDIWANELISYFPKGEVCSKMKILDIGTGPGFYSIIL 75

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
           ++RG+Q+   D S  M++ AK  A    ++DN++F+   AQ +    +   D+I+   + 
Sbjct: 76  SKRGYQMTAVDSSEGMLEEAKHNAGE--LADNIEFLCMDAQKL-DFEDNTFDVIVTRNLT 132

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMH----------------NMVAGNFD 166
             +  P    +    VL+P G+L     N +  L                    V  +  
Sbjct: 133 WNLPKPAEAYKEWKRVLKPNGILLNFDANWYSYLFDEEKEKEYQQDRLNTVKAGVEDHGA 192

Query: 167 YVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGK 205
           Y +  M +   R L     + P      L E G++ +  
Sbjct: 193 YEEGDMMEDISRCLPMGKVKRPQWDLAVLLECGFKTVSA 231


>UniRef50_Q3A5P1 Putative methyltransferase n=1 Tax=Pelobacter carbinolicus DSM 2380
           RepID=Q3A5P1_PELCD
          Length = 273

 Score =  146 bits (368), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 44/242 (18%), Positives = 85/242 (35%), Gaps = 16/242 (6%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVL-DAGGGEGQTA 59
           M     D + E+FS +     +          DL      + P +  +L D   G G TA
Sbjct: 1   MSKNFKDKVREQFSHSAESYVQSPGFAQG--DDLKEAARLLQPTQDDILLDVACGGGHTA 58

Query: 60  IKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFH 119
           +  A     V+  DL+ QM+ RA++    +G  +N+ F    A+D+         L+   
Sbjct: 59  LFFAPMVRSVVASDLAMQMLKRAQEFISEEGGVENVTFREADAEDLP-FPAGAFTLLTCR 117

Query: 120 AVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRT 179
                  D    L     VLR GG ++++           ++  + +  +     ++ R 
Sbjct: 118 IAPHHFPDVPRALAEFHRVLRRGGRMAIID---------TLLPEDPEIAEFMQTYEQMRD 168

Query: 180 LSPDYPRDPAQVYLWLEEAGW---QIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYC 236
            +        +    +E A +    I   +    F ++ +     RD  + L +L     
Sbjct: 169 PTHVRSYTKQEWSQMVEAADFILHDIEVVSKTHDFQEWAQRTGMNRDGVQKLNKLFIEAS 228

Query: 237 RQ 238
            +
Sbjct: 229 DK 230


>UniRef50_UPI0001AF209D methyltransferase type 11 n=1 Tax=Streptomyces ghanaensis ATCC
           14672 RepID=UPI0001AF209D
          Length = 277

 Score =  146 bits (368), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 62/254 (24%), Positives = 95/254 (37%), Gaps = 26/254 (10%)

Query: 17  IYGTTKGQLRQAILWQDLDRVLAEMG-PQKLRVLDAGGGEGQTAIKMAER-GHQVILCDL 74
            YG            +   +V+  +G     RVLDAG G G  A+ +AE  G  V    +
Sbjct: 35  WYGPDDDTPMAEASRRLTRKVVDALGVRAGQRVLDAGCGPGGPALLVAEETGADVTGVTV 94

Query: 75  SAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQT 134
           S        Q A A+G+SD ++F H    ++  H +   D ++    L++  D    L  
Sbjct: 95  SRFEAGAGTQKASARGLSDRVRFEHGDYAELGHHADGSFDAVMAMESLQYAPDLPRALAE 154

Query: 135 LWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLW 194
           L+ VLRPGG L++  Y                 V      +    L+  + +        
Sbjct: 155 LFRVLRPGGALTMTDY------------TLAARVPPAERDELAEKLTLPHLQPVEGWLEV 202

Query: 195 LEEAGWQIMGKT--GVRVF---HDYLREKHQQRDCYEALLELETRYCRQEPYITL----- 244
           L EAG+++   T  G RVF     Y+    + RD   A    E     +E          
Sbjct: 203 LREAGFRVEEYTQCGPRVFGLGAKYVEAAEEGRDALRAAFGEEAVAGLKEAMADFFSPGA 262

Query: 245 --GRYIHVTARKPQ 256
               Y  VT R+P+
Sbjct: 263 ERIEYSIVTVRRPR 276


>UniRef50_C8W4V3 Methyltransferase type 11 n=1 Tax=Desulfotomaculum acetoxidans DSM
           771 RepID=C8W4V3_DESAS
          Length = 249

 Score =  145 bits (367), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 55/234 (23%), Positives = 85/234 (36%), Gaps = 27/234 (11%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
           +  +   A ++S NI+       + A  W  L       G + L+VLD G G G  A+ +
Sbjct: 8   ENYWQGAASRYSNNIWKEMNSFKKDA--WAALIDEHRSAG-ESLKVLDIGTGPGFFAMLL 64

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
           +  GH V   D +  M+  A    +  G   ++QF    +  +    E   DLI+   + 
Sbjct: 65  SGMGHTVTAIDCTENMLVEAGYNVQKVGF--HVQFYKMDSHVL-DFPEGTFDLIVCRNLT 121

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDY-----VQAGMPKKK- 176
             + DP    +    VL+PGG L +   N H  L    +   +        Q G+P    
Sbjct: 122 WTLRDPVQAYREWHRVLKPGGKLMVFDANWHLRLFDPEMDRLYREDKERARQMGIPDSHD 181

Query: 177 ----------KRTLSPDYPRDPAQVYLWLEEAGW----QIMGKTG-VRVFHDYL 215
                      R L     R P      L EAG+         +G V   HD +
Sbjct: 182 QSNMEESDKIARQLYLSSRRRPDWDESALLEAGFCKLIIDEDISGKVWDAHDRV 235


>UniRef50_A4FLY1 Methyltransferase n=1 Tax=Saccharopolyspora erythraea NRRL 2338
           RepID=A4FLY1_SACEN
          Length = 244

 Score =  145 bits (367), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 56/240 (23%), Positives = 92/240 (38%), Gaps = 8/240 (3%)

Query: 22  KGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDR 81
           +      +L  +L +     G Q  RVLD GGG G  A+ +A  G  V + D S   +  
Sbjct: 2   RSDAVHRVLEAELAQARKRRGGQPPRVLDVGGGSGVWAVPLASAGCAVTVVDPSPNALAT 61

Query: 82  AKQAAEAKGVSDNMQFIHCAAQDVASH-LETPVDLILFHAVLEWVADPRSVLQTLWSVLR 140
            ++ A   GV+D +  +      + +   E   DL+L H +LE V D  + L+ + +   
Sbjct: 62  LQRRAADAGVADRITPLQGDTDALHAISPEGGADLVLGHGLLEVVDDVAAALREMAAATA 121

Query: 141 PGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL-----SPDYPRDPAQVYLWL 195
           PGG +S++  N H  ++   + G              R       +     D   V   +
Sbjct: 122 PGGAVSVLVANRHAAVLARALTGRVTEALKLFQDPDGRLHDCAADTLQRRFDSDSVERAM 181

Query: 196 EEAGWQIMGKTGVRVFHDYLREKHQQR--DCYEALLELETRYCRQEPYITLGRYIHVTAR 253
            EAG  +    G  V  D +     +      E+L ELE     + P   +   +H   R
Sbjct: 182 REAGMDVELIQGQGVLSDIVPGSVLESTTGAAESLAELERLAAARPPLRDIATRLHAIGR 241


>UniRef50_A1R990 Menaquinone biosynthesis methyltransferase ubiE n=56
           Tax=Actinobacteria (class) RepID=UBIE_ARTAT
          Length = 253

 Score =  145 bits (367), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 53/240 (22%), Positives = 92/240 (38%), Gaps = 28/240 (11%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           FDD+A K+       + GQ R+   W+ +  V A       +VLD   G G ++   A+ 
Sbjct: 17  FDDVAPKYDVVNDVLSMGQTRR---WRRIV-VDAMDVKVGQKVLDLAAGTGTSSEPYADA 72

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV 125
           G  V+ CD S  M+   K+         ++ FI   A ++    +   D       L  V
Sbjct: 73  GVDVVACDFSLGMLKVGKRR------RPDIDFIAGDATNLP-FADNSFDASTISFGLRNV 125

Query: 126 ADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPK-KKKRTLSPD- 183
            +PR  L+ +  V +PGG L +  ++   + +   +    +Y+   +P    K + +PD 
Sbjct: 126 VEPRKALEEMLRVTKPGGRLVIAEFSHPVVPLWRNLYT--EYLMRALPAIATKVSSNPDA 183

Query: 184 ---------YPRDPAQVYLWLEEAGWQIMGKT----GVRVFHDYLREKHQQRDCYEALLE 230
                       D   +  WL +AGW  +       G+   H   +    +     A L 
Sbjct: 184 YVYLAESIRAWPDQDHLAQWLSDAGWTDITYRNLSGGIVAVHRAQKPDEHRESVPVAKLR 243


>UniRef50_C6C7H1 Methyltransferase type 11 n=3 Tax=Enterobacteriaceae
           RepID=C6C7H1_DICDC
          Length = 258

 Score =  145 bits (366), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 42/163 (25%), Positives = 69/163 (42%), Gaps = 8/163 (4%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQK-LRVLDAGGGEGQTAIKM 62
           R +   A  +S+   G      R   +W  L ++L +   +  LRVLD G G G  A+ +
Sbjct: 18  RYWRGRAADYSQINIGELAMPKR--AVW--LAKILEQAPQKPVLRVLDIGTGPGFFAVTL 73

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
           A  GH+V   D++  M+D+A+  A     +  + F+H     +    +   DL++   V 
Sbjct: 74  ALAGHRVTAVDVTQAMLDQARANAAHYRTT--IDFVHSDVHALP-FADNGFDLVVSRNVT 130

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNF 165
             + DP+   Q    VL PGG L     N +  L        +
Sbjct: 131 WNLTDPQRAYQEWRRVLAPGGRLINFDANWYLQLFDASSRRGY 173


>UniRef50_D1C573 Methyltransferase type 11 n=1 Tax=Sphaerobacter thermophilus DSM
           20745 RepID=D1C573_SPHTD
          Length = 265

 Score =  145 bits (366), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 48/240 (20%), Positives = 91/240 (37%), Gaps = 14/240 (5%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRV-LDAGGGEGQTAI 60
            ++    + E+F+            ++    DL+R++         + LD   G G TA+
Sbjct: 7   AEQVKARVREQFAAAGDAYVVSPTHRSG--DDLERLVELAEATPETIALDIATGGGHTAL 64

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
            +A     V   DL  +M++RA+    ++GV  N  F    A+D+    +   DL+    
Sbjct: 65  ALAPHVRHVTATDLVPEMLERARAFITSQGV-INADFQVADAEDLP-FADGSFDLVTCRI 122

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
                AD +  +  +  VLRPGG+  L+          ++   + +  +     +++R  
Sbjct: 123 APHHFADVQRAVHEVARVLRPGGLFLLID---------SVAPEDPELDEFLNELERRRDP 173

Query: 181 SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP 240
           S       ++   +LE AG  +         HD+     + R   E    LE+      P
Sbjct: 174 SHVRSYRRSEWRQFLEAAGLTVEVMETFTKRHDFTAWTARSRLGPEGRAVLESWVLAAPP 233


>UniRef50_C6CNR0 Methyltransferase type 11 n=2 Tax=Dickeya RepID=C6CNR0_DICZE
          Length = 265

 Score =  145 bits (366), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 38/164 (23%), Positives = 69/164 (42%), Gaps = 8/164 (4%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKL-RVLDAGGGEGQTAIK 61
              +++ AE ++        G  R+  LWQ++  +L     + L  +LD G G G  A+ 
Sbjct: 24  KHYWNNRAEGYNEVNVAELAGGKRR--LWQEI--ILRHAPKKPLLNILDVGTGPGFFAVT 79

Query: 62  MAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
           +A  GH+V   D++  M+ +A+  A+   V   + F+      +    +   D+++   V
Sbjct: 80  LAMAGHRVTAVDVTPAMLAQARSNADYYDVE--IAFVATDVHALP-FPDNHFDVLVTRNV 136

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNF 165
              +  P S  Q    VL PGG L     N +  L +      +
Sbjct: 137 TWNLKQPLSAYQEWHRVLAPGGRLINFDANWYAHLFNAAAREGY 180


>UniRef50_D1VJQ5 Methyltransferase type 12 n=1 Tax=Frankia sp. EuI1c
           RepID=D1VJQ5_9ACTO
          Length = 296

 Score =  144 bits (365), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 75/268 (27%), Positives = 115/268 (42%), Gaps = 26/268 (9%)

Query: 16  NIYGTTKGQLRQAILWQDLDRVLAEMGPQKLR--------VLDAGGGEGQTAIKMAERGH 67
                 +   R A +W+ L  VLA                V+DAGGG G  A+ +AERGH
Sbjct: 27  AYRAAERADPRHAAVWRALTDVLAAGPAGTGAGPAGAGLTVVDAGGGSGGFAVPLAERGH 86

Query: 68  QVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVAS------HLETPVDLILFHAV 121
           +V++ D S   +    + A   GV+  +        ++++            DL+L HAV
Sbjct: 87  RVLVVDPSQDALAALARRAADAGVAARVTGRQGDLSELSAVVGPDLAAAGGADLLLCHAV 146

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGM-----PKKK 176
           L+ V DPR  L T+  VLRPGG LSL+     G ++   +AG FD     +     P   
Sbjct: 147 LDRVDDPRRALATVLRVLRPGGWLSLLVPGRAGTVLARALAGRFDEAAQALAGPYPPAPG 206

Query: 177 KRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLR-------EKHQQRDCYEALL 229
           +R     +  D  ++   +  AG +++   GVRV  D          E+       E L 
Sbjct: 207 RRLAGETHRFDTDEIVGLVRAAGAEVVAVHGVRVLTDLATPPAGGGDEREPAAGWAERLA 266

Query: 230 ELETRYCRQEPYITLGRYIHVTARKPQS 257
           +LE     + PY  L   +HV AR+ ++
Sbjct: 267 DLEAAVATRPPYRDLAAQLHVLARRTEA 294


>UniRef50_C7Q6F0 Methyltransferase type 11 n=1 Tax=Catenulispora acidiphila DSM
           44928 RepID=C7Q6F0_CATAD
          Length = 382

 Score =  144 bits (365), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 43/220 (19%), Positives = 75/220 (34%), Gaps = 17/220 (7%)

Query: 13  FSRNIYGTTKGQLRQAILWQDLDRVLAEMG-PQKLRVLDAGGGEGQTAIKMA-ERGHQVI 70
           +         G  R     + +  +++  G P   RVLD G G G  A+ +A   G  V+
Sbjct: 33  WDEGERPDADGADRHRATDRLVHELVSYAGVPDGARVLDVGCGIGGPALYLAGALGCAVV 92

Query: 71  LCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRS 130
              LSA    RA + A+  G++D  +F    A       +   D++     L  +AD  +
Sbjct: 93  GVTLSASQAARAGEKAQEAGLADRAEFHQLDALS-TGFPDASFDVLWAVESLMHIADREA 151

Query: 131 VLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQ 190
                  +LRPGG L++  ++     +        D +                     +
Sbjct: 152 FFAEAMRLLRPGGRLAIATWSQRDGELSQDEQELIDQILKHQVMPS--------FSSLEE 203

Query: 191 VYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLE 230
                  AG+  +         D+ R      D   AL++
Sbjct: 204 HERMANAAGFTEVAS------VDWSRAVANSWDPEFALIK 237


>UniRef50_A1TE65 Methyltransferase type 11 n=1 Tax=Mycobacterium vanbaalenii PYR-1
           RepID=A1TE65_MYCVP
          Length = 280

 Score =  144 bits (365), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 40/218 (18%), Positives = 75/218 (34%), Gaps = 12/218 (5%)

Query: 30  LWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA-ERGHQ--VILCDLSAQMIDRAKQAA 86
               +   +A     + ++LD G G G T + +A   G        D+S  MI  A+  A
Sbjct: 35  FEDLIVDSVAAAAGPREQILDLGCGTGATTLALAERLGAHGGCTGIDISEPMIHAARTRA 94

Query: 87  EAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLS 146
             + +   ++F+   AQ          D+++    + +  DP +  + L    RPGG L+
Sbjct: 95  RDRNLP--VEFVVGDAQSFPFQP-NTFDVMVSRFGVMFFDDPTTAFRNLRRATRPGGRLT 151

Query: 147 LMFY-NAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGK 205
            + + +       +        + + +      +  P    D  + +  L   GW  +  
Sbjct: 152 FVCWRDPTDNPFMSTAERAAAQLLSDLKPGIAGSPGPFAFADAHRTHSILRAGGWTAVDI 211

Query: 206 TGVRV-----FHDYLREKHQQRDCYEALLELETRYCRQ 238
             V V       D L    Q       L  ++ R   Q
Sbjct: 212 RPVDVTCTMQESDLLPYLTQMGPVGRTLRAVDARTRAQ 249


>UniRef50_B6IUU0 3-demethylubiquinone-9 3-methyltransferase n=4
           Tax=Alphaproteobacteria RepID=B6IUU0_RHOCS
          Length = 263

 Score =  144 bits (365), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 43/241 (17%), Positives = 94/241 (39%), Gaps = 18/241 (7%)

Query: 6   FDDIAEKFSRNIYGTT---------KGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEG 56
           F  +A ++       +            +R A+  +     +AE   + +R+LD G G G
Sbjct: 32  FSAMAAEWWDPRGKFSPLHKFNPVRLAYIRDALCDRWGRDPMAERPLEGIRILDVGCGGG 91

Query: 57  QTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLI 116
             A  +A  G +V+  D S + +  A   A   G +  + +    A+ +A+      D++
Sbjct: 92  LIAEPLARLGAEVVGIDASERNVKTAATHALETGTT--VDYRVGTAEALAA-TGERFDVV 148

Query: 117 LFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKK 176
           L   ++E VAD   +L  + ++ +  G+L +   N         + G  +YV   +P+  
Sbjct: 149 LALEIVEHVADVDLLLTAITTLTKQDGLLFMATVNRTAKSFVMAIVGA-EYVLRWLPRGT 207

Query: 177 KRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYC 236
                      P+++   L + G+ I   TG+   ++ + ++    +    +  +     
Sbjct: 208 HDW---RKFIRPSELATGLRQLGFGIKNLTGL--IYNPMTDRFSLAERDVDVNYMLYAAR 262

Query: 237 R 237
            
Sbjct: 263 D 263


>UniRef50_Q1D7Y1 Methyltransferase, UbiE/COQ5 family n=2 Tax=Myxococcales
           RepID=Q1D7Y1_MYXXD
          Length = 269

 Score =  144 bits (365), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 42/251 (16%), Positives = 78/251 (31%), Gaps = 19/251 (7%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIK 61
           Q   ++ +A ++ R +  T +   R+A+L   +         Q  RV+D   G G  A+ 
Sbjct: 9   QPEAWNLVAPEYVRELMPTFETFSREALLRAGVA--------QGTRVVDVATGPGTLALL 60

Query: 62  MAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
            A  G +V   D S +MI   +       +  ++  +      +        D       
Sbjct: 61  AARDGARVTAVDFSPEMIAALRGRTAEAKL--DVDILEGDGMALPFEA-NAFDAAFSMFG 117

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLS 181
           L +  D     Q L  VL+PGG   +  +                + Q G    +   + 
Sbjct: 118 LMFFPDRARGFQELHRVLKPGGRAVVSSWTPFERSKELRAVYTRLWEQMGAKPSQPGAIP 177

Query: 182 PDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDY-----LREKHQQRDCYEALLELETRYC 236
                DP      +  AG+  +    V    DY     + +   +      L        
Sbjct: 178 ---LSDPDTCQREMSSAGFTHVTVNEVEGSIDYPSTAAMVDATTRSSAPVVLARRALGPQ 234

Query: 237 RQEPYITLGRY 247
            +    ++  Y
Sbjct: 235 WEPLLWSMHEY 245


>UniRef50_A1UUE1 Ubiquinone/menaquinone biosynthesis methyltransferase ubiE n=55
           Tax=cellular organisms RepID=UBIE_BARBK
          Length = 260

 Score =  144 bits (365), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 34/218 (15%), Positives = 75/218 (34%), Gaps = 15/218 (6%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M D  F  +AE + R     + G     I    +   LA       +V+D  GG G  A 
Sbjct: 31  MVDGVFHSVAENYDRMNDILSLG--LHRIWKNSMITWLAPPAISGWKVIDVAGGTGDIAF 88

Query: 61  KM---AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLIL 117
           ++   + +     + D++  M++  K+ A+  G++  + F+   A+ +    +   D   
Sbjct: 89  RILNASRKKAHATVLDINHSMLNVGKKRAQINGLAPFIDFVEANAEQLP-FSDQSFDAYT 147

Query: 118 FHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDY---------V 168
               +  V      L   + VL+PGG    + ++   + + + +   + +         +
Sbjct: 148 IAFGIRNVPHIDKALSEAFRVLKPGGRFLCLEFSNVEMPLLDKLYDLWSFHAIPKLGQLI 207

Query: 169 QAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKT 206
                  +    S             +  AG+  +   
Sbjct: 208 AGNSDAYRYLVESIRMFPKQDDFACMINRAGFSRVSYR 245


>UniRef50_A4X7A0 Methyltransferase type 11 n=9 Tax=Bacteria RepID=A4X7A0_SALTO
          Length = 260

 Score =  144 bits (364), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 40/204 (19%), Positives = 72/204 (35%), Gaps = 12/204 (5%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M+  ++D+ A  +S                ++    +      Q  RVLDAG G G  + 
Sbjct: 29  MRADHYDNFARSYSIENESGF-----YNAYYERPAMLTLAGDVQGRRVLDAGCGSGPLSE 83

Query: 61  KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
            +  +G  V   D S  M++ A+       + ++               +   D ++   
Sbjct: 84  ALRAKGAIVTGFDSSPAMVELARTR-----LGEDADLQVADISLPLPFADGAFDDVVVSL 138

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFD--YVQAGMPKKKKR 178
           VL ++ D  + L  L  VL+PGG L L   +   L   +  A  F             + 
Sbjct: 139 VLHYLQDWGAALSELRRVLKPGGRLLLSVNHPRILESRDPNADYFSVTQHSGEYTFGDEH 198

Query: 179 TLSPDYPRDPAQVYLWLEEAGWQI 202
            +   + R    +     EAG++I
Sbjct: 199 VVLTFWHRPLHAMTDAFTEAGFRI 222


>UniRef50_B5JEA6 Methyltransferase domain family n=1 Tax=Verrucomicrobiae bacterium
           DG1235 RepID=B5JEA6_9BACT
          Length = 269

 Score =  144 bits (364), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 56/262 (21%), Positives = 101/262 (38%), Gaps = 29/262 (11%)

Query: 11  EKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLR-VLDAGGGEGQTAIKMAERGHQV 69
           E +SR   G  +G    A++ + +D +LAE   +     LD G G G TA   +E G + 
Sbjct: 16  ETWSRCASGYIEGF--GALVAEAIDSILAEASVKNGTFCLDVGTGPGNTAKSASELGART 73

Query: 70  ILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPR 129
           I  D S  M+  A+        +  ++F++ +A+ +    +   D ++ + +L    +P 
Sbjct: 74  IGIDFSDTMLAEARVR------NPELEFLNASAEKLP-FADDEFDAVVGNYILHHSGEPE 126

Query: 130 SVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPA 189
            +L   + VL+PGG  +   ++    L    +         G P      L      D  
Sbjct: 127 KILSDSFRVLKPGGKAAFTVWSKPEKLEAFGLFFGAVGEHLGSPDLPHGPL--FGISDFD 184

Query: 190 QVYLWLEEAGWQIMGKTG-------------VRVFHDY----LREKHQQRDCYEALLELE 232
             +  L EAG+                    +R FHD+    + +K  +    E +L+  
Sbjct: 185 HFHHLLREAGFTKTSVRELPTVWKTPSISSYLRAFHDWANLNVVDKEIREKIEETILKSS 244

Query: 233 TRYCRQEPYITLGRYIHVTARK 254
            RY  +  Y      I ++  K
Sbjct: 245 GRYQSEGVYYIPNPSILLSGTK 266


>UniRef50_B7QF56 Dihydroxypolyprenylbenzoate methyltransferase, putative (Fragment)
           n=1 Tax=Ixodes scapularis RepID=B7QF56_IXOSC
          Length = 247

 Score =  144 bits (364), Expect = 3e-33,   Method: Composition-based stats.
 Identities = 38/206 (18%), Positives = 71/206 (34%), Gaps = 19/206 (9%)

Query: 6   FDDIAEKFSRNIYGTT----KGQLRQAILWQDLDRVLAEM---------GPQKLRVLDAG 52
           FD +A ++       +       LR  ++   L +                  LR+LD G
Sbjct: 45  FDALAHRWWDPEGEFSTLSRMNTLRVPLIRDGLLQTRQPGEKVPKSLAKPLAGLRILDVG 104

Query: 53  GGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKG-VSDNMQFIHCAAQDVASHLET 111
            G G  +  +A  G  V   D +   I+ A+  AE    V D++ +     +++      
Sbjct: 105 CGGGLLSEPLARLGATVTGIDPTPGSIEVARAHAERDPEVRDSIVYEGVEIEELVQRS-V 163

Query: 112 PVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAG 171
             D ++   V+E V + R  +++  ++   GG L     N              +Y+   
Sbjct: 164 KFDAVVASEVVEHVQNYRDFVKSCVTLTEDGGSLFFTTINRTVQSFLIAKIAA-EYIFRL 222

Query: 172 MPKKKKRTLSPDYPRDPAQVYLWLEE 197
           +P         +    P Q+   LE 
Sbjct: 223 VPPGLHDW---NMFLPPEQLEEALEA 245


>UniRef50_Q01W19 Demethylmenaquinone methyltransferase n=1 Tax=Candidatus Solibacter
           usitatus Ellin6076 RepID=Q01W19_SOLUE
          Length = 272

 Score =  144 bits (364), Expect = 3e-33,   Method: Composition-based stats.
 Identities = 48/255 (18%), Positives = 84/255 (32%), Gaps = 26/255 (10%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           +Q   +D  AE++            R+ I    +  +         RVLD   G G    
Sbjct: 9   IQRYGWDKAAEEYEEYW--------RRQIEPAQMRLLELAALRPGERVLDIACGTGLITF 60

Query: 61  KMAERGHQ---VILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLIL 117
             A        V+  D+SA MIDR ++ A  +G++ N+ F    A+ +    E   D   
Sbjct: 61  PAAIAVGMEGLVVGTDISAGMIDRGREEAAKRGLA-NVTFQRVDAEAL-DFPENSFDAAF 118

Query: 118 FHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKK 177
               L +V +P   L+ + + L+PGG ++   +          +    D        K +
Sbjct: 119 CSLGLMYVPEPLKALRQMRNALKPGGRMAASVWGQRERCGWAGIFPVVDAR-----VKSE 173

Query: 178 RTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYE--------ALL 229
                        +   LE  G+  +    +    DY  E+      +         A  
Sbjct: 174 VCPMFFQLGTADNLRAALEMTGFCDIEVERLATMLDYASEEEAIGAAFAGGPVALAYAHF 233

Query: 230 ELETRYCRQEPYITL 244
           + E R      Y+  
Sbjct: 234 DAEIREEAHAEYLGT 248


>UniRef50_A4Z3A6 Putative uncharacterized protein n=1 Tax=Bradyrhizobium sp. ORS278
           RepID=A4Z3A6_BRASO
          Length = 242

 Score =  144 bits (364), Expect = 3e-33,   Method: Composition-based stats.
 Identities = 48/230 (20%), Positives = 89/230 (38%), Gaps = 13/230 (5%)

Query: 7   DDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERG 66
           D+IA  +   ++ +   + R A ++     +L +      R LDAG G G  +  +A RG
Sbjct: 20  DNIAANWE-TLHRSRTFRARTAAMFG----LLEQQDLSGQRWLDAGCGTGTLSRLLAGRG 74

Query: 67  HQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIH-CAAQDVASHLETPVDLILFHAVLEWV 125
            +V   D SA+MI RA+        +  ++F      + +    +   D +L  +VLE+V
Sbjct: 75  CEVTGVDASAEMIRRARHLPTGSEQTGALRFDQIATIEALP-FSDGAFDGVLCASVLEYV 133

Query: 126 ADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYP 185
            D  + L+ +  VLR  G++ L   N    L+       F        +   R LS    
Sbjct: 134 PDVPAALREIHRVLRVDGLVLLSIPNR-ASLLRQAFKLAFAVSSRAWTRPMFRYLSVSKF 192

Query: 186 -RDPAQVYLWLEEAGWQIMGK----TGVRVFHDYLREKHQQRDCYEALLE 230
                     +++ G+ ++      T +  F D+        +     + 
Sbjct: 193 DASATTATHLMQDIGFSVLALNFSGTPLPAFLDHTPRFGTLMNILARRMA 242


>UniRef50_Q5UF03 Predicted 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol
           methylase n=1 Tax=uncultured alpha proteobacterium
           EBAC2C11 RepID=Q5UF03_9PROT
          Length = 246

 Score =  144 bits (363), Expect = 3e-33,   Method: Composition-based stats.
 Identities = 42/216 (19%), Positives = 78/216 (36%), Gaps = 20/216 (9%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLA---------EMGPQKLRVLDAG 52
            D+ +D+                +R   + + + R                  L++LD G
Sbjct: 17  SDQWWDEKGP----MAPLHAFTPIRIDYILRAIRRFFPIQTRMLDNDNAVLGGLKILDIG 72

Query: 53  GGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETP 112
            G G  A  MA  G  V   D++   +  AK  A+   +S  + +   +A+++A      
Sbjct: 73  CGGGLLAEPMARLGASVTGIDVTDAAVTAAKTHAKTMQLS--INYQTISAEELAK-SGVI 129

Query: 113 VDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGM 172
            D+I    V+E VAD    ++ +  +L P GV+ +   N     +        +Y+   +
Sbjct: 130 FDVIYASEVIEHVADRPIFVKAIAQMLAPNGVVIITTINRSLPALIFA-KFALEYIARIV 188

Query: 173 PKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
           P        P     P ++     +AG  +   TG 
Sbjct: 189 PVGTHD---PRKFVKPNELRAEFVDAGILLDDMTGF 221


>UniRef50_B1I444 Methyltransferase type 11 n=1 Tax=Candidatus Desulforudis
           audaxviator MP104C RepID=B1I444_DESAP
          Length = 215

 Score =  144 bits (363), Expect = 4e-33,   Method: Composition-based stats.
 Identities = 40/207 (19%), Positives = 75/207 (36%), Gaps = 29/207 (14%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           M+   F+++A+++   +      +L + +    L         +   VLD G G G    
Sbjct: 1   MRREFFNNLADRWDDLVPPGAASKLAEIVAGSGLR--------KGAHVLDVGCGTGLLVP 52

Query: 61  KMAERGHQ---VILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLIL 117
            + ER  +   V   D +A M+ RA   A       N++F+      +        D + 
Sbjct: 53  FLLERAGERGTVTGVDFAAAMVQRAGAKA----FGPNVRFVEADVAALPFEP-GTFDAVF 107

Query: 118 FHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKK 177
            + VL  + D    LQ L  VL+PGG+L +                        M +   
Sbjct: 108 CNNVLPHLPDKPGALQELNRVLKPGGLLVIC-------------HTESREAVNRMHRHIG 154

Query: 178 RTLSPDYPRDPAQVYLWLEEAGWQIMG 204
             +  D      ++   L++AG+ ++ 
Sbjct: 155 GPVGADLLPTVEELRQMLQDAGYSVLD 181


>UniRef50_B0C5W7 3-demethylubiquinone-9 3-methyltransferase n=2 Tax=Cyanobacteria
           RepID=B0C5W7_ACAM1
          Length = 244

 Score =  143 bits (362), Expect = 4e-33,   Method: Composition-based stats.
 Identities = 45/214 (21%), Positives = 83/214 (38%), Gaps = 12/214 (5%)

Query: 1   MQDRN---FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQ 57
           M+  N   +D  A+++               + +Q  DR + +     L+VLD G G G 
Sbjct: 1   MERNNLAFYDQQADQWWNETATIFPLSKLNPLRFQYFDRFIQDW--NGLKVLDVGCGGGY 58

Query: 58  TAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLIL 117
           T   +A+RG  V   D SA  I+ AK+ AE  G++  + +     + +        D+++
Sbjct: 59  TCEFLAQRGATVTGIDPSAACIEAAKRHAEQMGLT--IDYHVGMGETLP-FGNDCFDVVV 115

Query: 118 FHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKK 177
              VLE V    + +  +  V+ PGG+      N        ++    + V   +P+   
Sbjct: 116 CVDVLEHVKSVATTVTEISRVIGPGGLFCFDTINRTWQS-RWLMIWLLEDVLRQIPRGIH 174

Query: 178 RTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVF 211
                     P  ++  L   G+  +   G  +F
Sbjct: 175 DW---HQFVPPEDLHQQLVHVGFSQVTLQGFDLF 205


>UniRef50_UPI00006A654D PREDICTED: similar to Hexaprenyldihydroxybenzoate
           methyltransferase, mitochondrial precursor
           (Dihydroxyhexaprenylbenzoate methyltransferase)
           (3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase)
           (DHHB methyltransferase) (DHHB-MTase) (DHHB-MT)... n=1
           Tax=Ciona intestinalis RepID=UPI00006A654D
          Length = 300

 Score =  143 bits (362), Expect = 4e-33,   Method: Composition-based stats.
 Identities = 38/212 (17%), Positives = 72/212 (33%), Gaps = 13/212 (6%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMG---------PQKLRVLDAGGGEG 56
           F  +AE +               +    +   L  MG          Q +++L+ G G G
Sbjct: 59  FSKLAENWWDENGAMKALHSMNRVRVPFIRDGLISMGCGEPYTSKPLQGIKILEVGCGAG 118

Query: 57  QTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLI 116
                +A  G  V+  D S  +++ AK   +      ++Q+I    +D+          +
Sbjct: 119 VLCEPLARLGASVLGIDASDNVLEVAKIHRDGNTELSDLQYIDADLEDIVGAGTLRFHAV 178

Query: 117 LFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKK 176
           +   V+E V D    +    S+L P G L L   N   +     V    + V   +P   
Sbjct: 179 VASEVVEHVEDKTKFINNCCSLLMPNGSLFLSTINRTQVSYLLAVLMA-EEVLGVVPPGT 237

Query: 177 KRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
                 +      ++  +L +   +I    G+
Sbjct: 238 HDW---EMFVTTDEIKSYLNQGNCEIQKIVGM 266


>UniRef50_P67065 Menaquinone biosynthesis methyltransferase ubiE n=2 Tax=Tropheryma
           whipplei RepID=UBIE_TROW8
          Length = 239

 Score =  143 bits (361), Expect = 6e-33,   Method: Composition-based stats.
 Identities = 42/210 (20%), Positives = 78/210 (37%), Gaps = 17/210 (8%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
           + F+ +A+ + R         L+ A   +   ++L         VLD G G G +   +A
Sbjct: 21  KMFNRVAQAYDRTN--LVLSFLQDAHWRRAACKMLGVT--AGEEVLDVGAGTGASTRTVA 76

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
             G  V   D+S +M+  A+   +      N+ +      D+    +   D IL    L 
Sbjct: 77  RTGAAVTGIDISPRMLQIARNRCKRFQ---NITWRLTNG-DLP-FPDKSFDAILMVFCLR 131

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPK--------K 175
            V++ +  L     VL+PGG L +  ++     +         YV   + K         
Sbjct: 132 NVSNIQGFLCDAARVLKPGGRLVVCEFSHPRRFVAPFYRLYLRYVLPRLAKLISSDPAAY 191

Query: 176 KKRTLSPDYPRDPAQVYLWLEEAGWQIMGK 205
           +  T S +   +  ++   LE+ G+Q    
Sbjct: 192 EYLTESIEDWYEVDELAFMLEQCGFQNTSW 221


>UniRef50_A2R6K2 Catalytic activity: S-adenosyl-L-methionine + 5alpha-cholesta-8 n=5
           Tax=Leotiomyceta RepID=A2R6K2_ASPNC
          Length = 304

 Score =  143 bits (361), Expect = 6e-33,   Method: Composition-based stats.
 Identities = 55/254 (21%), Positives = 90/254 (35%), Gaps = 16/254 (6%)

Query: 13  FSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE-RGHQVIL 71
           +    +           +   L R L    P    VLDAG G    AI MA   G +V  
Sbjct: 42  YEPGCWWPFPITAALRKMEDHLARSLNL--PPGATVLDAGCGYAHVAIHMARKHGLRVTG 99

Query: 72  CDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSV 131
            D+  + + R K+   A G+S+++         + +  +   D +          DP++ 
Sbjct: 100 IDVIDRHVTRGKENVRAAGLSNSVSLQKGDYHHLENFADRTFDGLYTMETFVHATDPKAA 159

Query: 132 LQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQV 191
           LQ    VL PGG ++L  Y+   +   N+               K   +  +   +   +
Sbjct: 160 LQEFCRVLAPGGSIALYEYDHINIAGDNITEDMRRQFAQIN---KYAAMPANISFEQGTL 216

Query: 192 YLWLEEAGWQIMGKTG--------VRVF--HDYLREKHQQRDCYEALLELETRYCRQEPY 241
              LE+AG+  +  T         +R+F    Y+          E              Y
Sbjct: 217 QSLLEDAGFIEIQSTDLTENVKPMLRLFFIVAYIPFLLISFFGLEKYFINAVAAVMGYRY 276

Query: 242 ITLGRYIHVTARKP 255
           + + RYI VTARKP
Sbjct: 277 LYMHRYICVTARKP 290


>UniRef50_Q846Y0 Monensin 3-O-methyl transferase n=1 Tax=Streptomyces cinnamonensis
           RepID=Q846Y0_STRCM
          Length = 276

 Score =  143 bits (360), Expect = 8e-33,   Method: Composition-based stats.
 Identities = 50/260 (19%), Positives = 93/260 (35%), Gaps = 32/260 (12%)

Query: 12  KFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKL-RVLDAGGGEGQTAIKMAE-RGHQV 69
            +     G  +       + Q  D ++  + P    RVLD G G G  A+++A  R  +V
Sbjct: 33  HYGYWFDGGEQQATFDEAMVQMTDEMIRRLDPAPGDRVLDIGCGNGTPAMQLARARDVEV 92

Query: 70  ILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPR 129
           +   +SA+ ++R  + A   G++D ++F    A ++    +   D       +  + D +
Sbjct: 93  VGISVSARQVERGNRRAREAGLADRVRFEQVDAMNLP-FDDGSFDHCWALESMLHMPDKQ 151

Query: 130 SVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPA 189
            VL     V++PG  + +            MV  N D  +         T       D  
Sbjct: 152 QVLTEAHRVVKPGARMPIAD----------MVYLNPDPSRPR-TATVSDTTIYAALTDIG 200

Query: 190 QVYLWLEEAGWQIMGKTGV-----RVFHDYLREKHQQRDCYEALLELE---------TRY 235
                   AGW ++  T +     + +  Y+      RD Y  ++ +E            
Sbjct: 201 DYPDIFRAAGWTVLELTDITRETAKTYDGYVEWIRAHRDEYVDIIGVEGYELFLHNQAAL 260

Query: 236 CRQEPYITLGRYIHVTARKP 255
            +         YI  TA++P
Sbjct: 261 GKMPEL----GYIFATAQRP 276


>UniRef50_A7AUT3 Ubiquinone biosynthesis O-methyltransferase family protein n=2
           Tax=Babesia bovis RepID=A7AUT3_BABBO
          Length = 556

 Score =  142 bits (359), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 39/190 (20%), Positives = 78/190 (41%), Gaps = 20/190 (10%)

Query: 43  PQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQA--------AEAKGVSD- 93
              +R+LD G G G  +  +A+ G  V+  D S ++I+ AKQ             G+SD 
Sbjct: 101 LNGVRILDVGCGGGILSEILAKCGAHVVGIDPSKELIEVAKQHRDTDLVYDCAKLGLSDE 160

Query: 94  ---NMQFIHCAAQDVAS-HLETPVDLILFHAVLEWVAD--PRSVLQTLWSVLRPGGVLSL 147
              N+++I    +  A  H +   D+++   V+E V +   ++ + ++  + +PGG++  
Sbjct: 161 CSRNLEYIQGTVESYAQSHHKELFDIVVASEVIEHVPNIQKQAFIDSIARLTKPGGLVVF 220

Query: 148 MFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTG 207
                        + G  + V   +PK   R         P  +      +G   + + G
Sbjct: 221 TTPGRSLKSCVINI-GFAERVFKTVPKDTHRY---TLFVSPESLSRSCANSGLSELCRQG 276

Query: 208 VRVFHDYLRE 217
           +  +  Y+R 
Sbjct: 277 I-FYLPYIRR 285


>UniRef50_A7HZC3 Ubiquinone/menaquinone biosynthesis methyltransferase n=2
           Tax=cellular organisms RepID=A7HZC3_PARL1
          Length = 262

 Score =  142 bits (359), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 40/215 (18%), Positives = 75/215 (34%), Gaps = 14/215 (6%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           F+ +A ++         G L +A     +D +    G +   ++D  GG G  A +  ER
Sbjct: 37  FEQVASRYDLMN-DLMSGGLHRAWKQSMIDWLNPPRGARPFHLIDVAGGTGDIAFRFLER 95

Query: 66  GH---QVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
                QV +CD++  M+   +  AEAK     ++F    A+ +    +   D       +
Sbjct: 96  AGVASQVTVCDINEHMLGVGQGRAEAKAFEGRIEFACGDAEHLP-FPDNSFDAYTIAFGI 154

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNA---------HGLLMHNMVAGNFDYVQAGMP 173
             V      L+  + VL+PGG    + ++          +       +     +V     
Sbjct: 155 RNVTHVDQALREAYRVLKPGGRFLCLEFSRVAVPGIDDIYEAYSFAAIPRMGKWVTGDDA 214

Query: 174 KKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
             +    S     D       + EAG+  +    V
Sbjct: 215 PYQYLVESIRRFPDQETFKRMIGEAGFGNVSYRNV 249


>UniRef50_B0A8V0 Putative uncharacterized protein n=1 Tax=Clostridium bartlettii DSM
           16795 RepID=B0A8V0_9CLOT
          Length = 247

 Score =  142 bits (359), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 43/208 (20%), Positives = 85/208 (40%), Gaps = 16/208 (7%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGP-QKLRVLDAGGGEGQTAIK 61
           +  +   ++ F        K   RQ  LWQ  D ++A +   + L++LD G G G  ++ 
Sbjct: 13  ENYWSKRSDDFFDLRIEELKSDKRQ--LWQ--DEIIANLPDKEHLKILDVGCGPGFFSVI 68

Query: 62  MAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
           ++  GH VI  DL+  MI +A + A+   +  ++ F    AQ++    +   D+++   +
Sbjct: 69  LSSLGHDVIGIDLTESMIQKADEIADI--LDYDIDFRVMNAQEL-DFDDEEFDVVISRNL 125

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKK----- 176
              + D     +  + VL+  GVL     +   + +   +    +     M         
Sbjct: 126 TWTLPDIEKAYKEWYRVLKKDGVLLNFDADYGKVSLKEEMKSLGEEHSHNMMDSSLVKEC 185

Query: 177 ---KRTLSPDYPRDPAQVYLWLEEAGWQ 201
              K+ L     R P     +L+E G++
Sbjct: 186 DDIKQELEISKRRRPMWDEKFLQEIGFE 213


>UniRef50_Q9K8W5 BH2887 protein n=1 Tax=Bacillus halodurans RepID=Q9K8W5_BACHD
          Length = 261

 Score =  142 bits (358), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 38/191 (19%), Positives = 74/191 (38%), Gaps = 12/191 (6%)

Query: 16  NIYGTTKGQLRQAILWQDLDRVLAEMGPQKLR-VLDAGGGEGQTAIKMAERGHQVILCDL 74
           + +       R   +    + ++  + P++   VLD G G G    ++ + G +VI  D+
Sbjct: 11  DDWNAKLYDERHRFVSAYGEDLIQWLAPKEGECVLDLGCGTGDLTEQIHQLGSRVIGVDV 70

Query: 75  SAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQT 134
           S  MI++AK      G   ++ F    A D++       D I  +AVL W+ D    L  
Sbjct: 71  SESMIEQAK------GKFPHLDFQVAEATDLSF--SEKFDAIFSNAVLHWIKDAEEALTV 122

Query: 135 LWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLW 194
           ++  L+PGG     F     +     +        +    +  +   P +     Q    
Sbjct: 123 IYRSLKPGGRFVAEFGGKGNVE---TIVNTLADTMSQADSRWSKEELPWFFPSIGQYTSL 179

Query: 195 LEEAGWQIMGK 205
           +E+ G+++   
Sbjct: 180 MEQVGFRVTHA 190


>UniRef50_Q75FL1 Menaquinone biosynthesis methyltransferase ubiE n=6 Tax=Leptospira
           RepID=UBIE_LEPIC
          Length = 249

 Score =  142 bits (358), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 44/232 (18%), Positives = 83/232 (35%), Gaps = 15/232 (6%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM-- 62
           NF+ IA+K+ R  +      L   +    L R +       L VLD   G G  ++++  
Sbjct: 19  NFNKIAKKYDR--FNDWNSFLLHRVWKNHLVREIENNFSGHLHVLDLCCGTGDISLRLEN 76

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
           +     V   D S  M++ AK   + +     + F    A  +     +  D++     L
Sbjct: 77  SSFVDHVTCVDFSENMLEIAKTRLKKQAQKGRVHFELGDATKLIQFQNSQFDVVSIGFGL 136

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNF--------DYVQAGMPK 174
             V +    +  ++ VL+PGG+   +            +A  +         Y+  G   
Sbjct: 137 RNVDNLSKAIGEIFRVLKPGGMFLNLDVGKVKNPWIRWIADFYFFKIVPILGYILWGGKN 196

Query: 175 KKKRTLSPDYPRDPAQ--VYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDC 224
           +    L       P Q  + L LE+ G+Q +      VF + +    ++   
Sbjct: 197 EMFDYLPVSSLSYPDQETLQLILEKEGFQRVQYKNF-VFGNVVLHVAKKPSE 247


>UniRef50_C4G5R9 Putative uncharacterized protein n=1 Tax=Abiotrophia defectiva ATCC
           49176 RepID=C4G5R9_ABIDE
          Length = 265

 Score =  142 bits (358), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 47/276 (17%), Positives = 99/276 (35%), Gaps = 31/276 (11%)

Query: 1   MQDRN---------FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDA 51
           M++R          FD+      + +  + +GQL   I    +D+          ++L+ 
Sbjct: 1   MENRIEMLRTIYGKFDE-----DKRLTASRQGQLEYFITMNYVDKY----TKPGDKILEI 51

Query: 52  GGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLET 111
           G G G+ +I++A+ G+ V   +L    ++  K+ AE     +N+      A ++ S  + 
Sbjct: 52  GAGTGRYSIELAKNGYDVTAVELVESNLEVLKKNAEGL---ENISAFQGDALNLGSFDDN 108

Query: 112 PVDLILFHAVLEWV---ADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYV 168
             D+ L    +  +    D    L     V +P GV+ + F + H ++M N ++ NF   
Sbjct: 109 TFDVTLVFGPMYHLYEEKDRHKALDEAIRVTKPDGVILVAFLSVHAIMMSNYLSVNFKEG 168

Query: 169 QAGMPKKK----KRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYL---REKHQQ 221
                 +       T       D A+     E    + +         +      +    
Sbjct: 169 FTANFDEDYKVKHFTEQAFTGFDIAEFEEMFEAKPVEYITTVAADSILEIAERNPDFKMS 228

Query: 222 RDCYEALLELETRYCRQEPYITLGRYIHVTARKPQS 257
            + +   L  +   C +   + L  ++    RK + 
Sbjct: 229 DEDFGLFLNYQMNICEKREMLGLSSHLLYICRKIRC 264


>UniRef50_B2JBN9 Methyltransferase type 11 n=2 Tax=Cyanobacteria RepID=B2JBN9_NOSP7
          Length = 278

 Score =  142 bits (358), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 41/204 (20%), Positives = 78/204 (38%), Gaps = 15/204 (7%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
               IA+ +SR       G     I  + ++           +VLD   G G  A++ A+
Sbjct: 10  YKQQIADLYSRRSSTYDNGDWHPRIAHRLVEY---AHIRPGQQVLDIATGTGMVALEAAQ 66

Query: 65  RGH---QVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
                 +VI  D+S  M+++A++   A G+S N++F    A+ +        D I   + 
Sbjct: 67  IVGAEGRVIGVDISTGMLEQARRKVAALGLS-NVEFQLADAEAL-DFPLNSFDYIFCSSA 124

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLS 181
           L W++D    L+  + +L+P G+L    +     +   +        Q  + K     L 
Sbjct: 125 LIWMSDLVGALRLWYGLLKPKGLLGFHAFADTAFIEGVV-------AQRVLEKYGVSLLF 177

Query: 182 PDYPRDPAQVYLWLEEAGWQIMGK 205
                   +    L+ AG+  +  
Sbjct: 178 SKPTGTVEKCQKMLQLAGFSEIEI 201


>UniRef50_A8ICE1 Hexaprenyldihydroxybenzoate methyltransferase (Fragment) n=1
           Tax=Chlamydomonas reinhardtii RepID=A8ICE1_CHLRE
          Length = 263

 Score =  142 bits (358), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 48/204 (23%), Positives = 82/204 (40%), Gaps = 11/204 (5%)

Query: 38  LAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKG-VSDNMQ 96
           +  M P  LRVLD G G G  +  +A  G QV   D++ + ++ A+  A A   V++ ++
Sbjct: 1   MPHMRPTGLRVLDVGCGGGILSESLARLGAQVTGIDVTRENVEAARLHAAADPAVAERVR 60

Query: 97  FIHCAAQDVASHLETP----VDLILFHAVLEWVADPRSVLQTLWSVL--RPGGVLSLMFY 150
           +   + +D+A+          D +L   VLE VA P + +  L S+L  RPG  + +   
Sbjct: 61  YEVISVEDLAAAAAGGTTGLYDAVLASEVLEHVARPHAFVGVLASLLAPRPGASVIISTL 120

Query: 151 NAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRV 210
           N        +     +YV   +P       S      P ++ +  + AG Q+    G+  
Sbjct: 121 NRT-PAAWAVAIAGAEYVTGVVPVGTH---SWKKFITPEELAIMGDAAGLQVWHAAGMAP 176

Query: 211 FHDYLREKHQQRDCYEALLELETR 234
               L            +  L  R
Sbjct: 177 LGPALSWTLTPDLGVNYIASLRRR 200


>UniRef50_B8GH63 Methyltransferase type 11 n=1 Tax=Methanosphaerula palustris E1-9c
           RepID=B8GH63_METPE
          Length = 270

 Score =  142 bits (358), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 40/203 (19%), Positives = 83/203 (40%), Gaps = 16/203 (7%)

Query: 8   DIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMG-PQKLRVLDAGGGEGQTAIKMAERG 66
           ++AE++ +   G           + +   ++A +G  +   VLD G G G+   ++A+  
Sbjct: 12  ELAERYDQVSEGQ----------YNNGLTLIANLGVKKGQTVLDIGCGTGRLTSRVAKIV 61

Query: 67  H---QVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
               QVI  D S + I+ A++       S N+      A  +        D++  + V  
Sbjct: 62  GDTGQVIGIDPSKERIEIARRNVPDSPRS-NISLEIGDANSLYHFQNNSFDIVYLNIVFH 120

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPD 183
           W+ + +  L  ++ VL+PGG+L +   N        ++A      Q    +  ++  +  
Sbjct: 121 WIDNKKDALSQIYRVLKPGGLLGITTGNRDQPHTVTIIADRI-LTQPKYARSAQQGRASS 179

Query: 184 YPRDPAQVYLWLEEAGWQIMGKT 206
            P +  ++   L   G+ I+  T
Sbjct: 180 KPVNVLEMVSLLHATGYSILDIT 202


>UniRef50_D0LH47 Ubiquinone/menaquinone biosynthesis methyltransferase n=1
           Tax=Haliangium ochraceum DSM 14365 RepID=D0LH47_HALO1
          Length = 269

 Score =  142 bits (358), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 42/234 (17%), Positives = 83/234 (35%), Gaps = 17/234 (7%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           FD IA ++       + G  R+   W+       E+GP   RVLD   G    A+ +A  
Sbjct: 33  FDGIAPRYDLLNRVMSFGMDRR---WRRKTVEALELGP-GARVLDLATGTADVAMSIARS 88

Query: 66  G--HQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
               +V+  D SA M+D  ++   ++ + D +      AQ++  + +   D +     + 
Sbjct: 89  HPECEVVGVDPSAGMLDIGREKIASEQLEDRVSLALGDAQEL-DYPDDSFDGVCIAFGIR 147

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMF--------YNAHGLLMHNMVAGNFDYVQAGMPKK 175
            V D    L  +  + RPGG ++++                  + +      + +G  + 
Sbjct: 148 NVPDRARALAEMARITRPGGRVAILELSEPRRGLIAPLARFHIHHLVPRLGAMLSGSNEY 207

Query: 176 KKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV--RVFHDYLREKHQQRDCYEA 227
           +    S      P      +  AG  ++    +     H Y+      +D    
Sbjct: 208 RYLQSSIAAFPPPESFADMMRAAGMDVLLVKPMSFGACHLYVGTPAPSQDEGAQ 261


>UniRef50_B0C3T5 Methyltransferase n=8 Tax=Bacteria RepID=B0C3T5_ACAM1
          Length = 214

 Score =  142 bits (358), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 45/255 (17%), Positives = 91/255 (35%), Gaps = 44/255 (17%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIK 61
             + +D IAEK+++         +     +Q   ++  E     + VL+ G G G TAI 
Sbjct: 4   STQFWDKIAEKYAKQP-------ISDEAAYQKKLQITREYFQPSMNVLEFGCGTGSTAIA 56

Query: 62  MAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
            A   H +   D S++MID A+  A A+ +  N+ F   +  ++ +  ++  D +L   V
Sbjct: 57  HAPYVHHIQAIDFSSKMIDIAQAKAAAQNI-LNVTFEQASIDEL-NVPDSSYDAVLGLNV 114

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLS 181
           L  + +  + +  +  +L+PGG            +    +      V    P        
Sbjct: 115 LHLLENKEAAIAQVHKMLQPGGCFITSTVCLGDTMAWFKLIAPVGKVLGLFPL------- 167

Query: 182 PDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPY 241
                    +   L +AG++I                           + + +    +  
Sbjct: 168 -VKIFTVKDLETSLTDAGFEI---------------------------DYQWQAGDYQSP 199

Query: 242 ITLGRYIHVTARKPQ 256
           I   + + + A+KP 
Sbjct: 200 IGNAKILFIVAKKPA 214


>UniRef50_C9N657 Methyltransferase type 11 n=2 Tax=Streptomyces RepID=C9N657_9ACTO
          Length = 273

 Score =  142 bits (358), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 47/264 (17%), Positives = 87/264 (32%), Gaps = 32/264 (12%)

Query: 14  SRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCD 73
              +  +  G++  A   + L R L    P   RVLD GGG G  A  + + G++V L D
Sbjct: 21  DDRLRSSADGRMELARTQELLRRFL---PPAPARVLDVGGGTGIHAEWLVKDGYEVTLVD 77

Query: 74  LSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPR---S 130
              + +  A     A         +   A+ +    +   D++     L  + DP     
Sbjct: 78  PVPRHVKSAAAVCSA---------LAGDARALPQ-PDGSFDVVQLLGPLYHLPDPDDRRK 127

Query: 131 VLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNF---------DYVQAGMPKKKKRTLS 181
            L     V++PGG+++    N +  L  ++   +            +         R  +
Sbjct: 128 ALAEARRVVKPGGLIAAAAINRYASLFEHVTYAHLHTERIHDSVSKILETAVYDGVRGFT 187

Query: 182 PDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCY----EALLELETRYCR 237
             Y     ++   L  +G   +   G+      L +  +Q+       + +         
Sbjct: 188 LSYFHRAEELAAELTASGLTGVQVFGIEGPAWSLVKAAEQQPGEGPTDDLIASAMAAARL 247

Query: 238 QEPYITL---GRYIHVTARKPQSK 258
            EPY  L     +I    R P   
Sbjct: 248 AEPYPELLAASSHILAVGRAPADM 271


>UniRef50_UPI0001A4295A methyltransferase type 11 n=1 Tax=Pectobacterium carotovorum subsp.
           carotovorum WPP14 RepID=UPI0001A4295A
          Length = 264

 Score =  142 bits (358), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 42/226 (18%), Positives = 93/226 (41%), Gaps = 11/226 (4%)

Query: 40  EMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIH 99
           +    K +++D GG  G  + ++A+ GH+V L D++   I++AK+ +   GV  +  F  
Sbjct: 37  KHLLGKQKIIDIGGATGIYSFELAKLGHEVDLFDIAPIHIEKAKKISAETGVDLH-GFHI 95

Query: 100 CAAQDVASHLETPVDLILFHAVLEWVAD---PRSVLQTLWSVLRPGGVLSLMFYNAHGLL 156
             AQ++A   +   D ++ H  L  + D      VL+  + V++P G+L     N +  +
Sbjct: 96  GDAQNLA-FSDNSFDTVILHGPLYHITDESLRLRVLKEAYRVMKPEGILFAFAINRYAGV 154

Query: 157 MHNMVAG------NFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRV 210
            + +          F+ +   +    +      +   P ++   + ++G++ +   GV  
Sbjct: 155 FYGIQRELILNDPYFEMISNEVKTGFRERSPSWHFHLPQEMEAEVSKSGFRDIQMKGVVG 214

Query: 211 FHDYLREKHQQRDCYEALLELETRYCRQEPYITLGRYIHVTARKPQ 256
               L +   +    +   ++       E    +G+     ARK  
Sbjct: 215 PIWMLPDIESRLGDEQTRQKILRVSELLENEPIIGQDFVCIARKTN 260


>UniRef50_Q67LB5 Conserved domain protein n=1 Tax=Symbiobacterium thermophilum
           RepID=Q67LB5_SYMTH
          Length = 268

 Score =  142 bits (358), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 46/203 (22%), Positives = 75/203 (36%), Gaps = 17/203 (8%)

Query: 8   DIAEKFSR--NIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQ----TAIK 61
            +A  +SR   +Y    G    A + + L  V     P    +LD G G G      A  
Sbjct: 7   RLAMGYSRTSALYDLLAGHGYLAAIRRLLPLVRVRHRPA---ILDVGCGTGLNLFEAARW 63

Query: 62  MAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
            A  G  V   DLS  M+  A   A   G+   +  +   A+ +    +   DL+L ++V
Sbjct: 64  FAPTGPLV-GIDLSPGMVAVAAAKARQLGIPATI--LLGDAERLP-LPDASFDLVLCNSV 119

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLS 181
             W  D  + ++ +  VL+PGG L+L+   A G     ++      V         R   
Sbjct: 120 FHWFRDRPAAMREMARVLKPGGQLALITATAPGFREWFLLIDAVIRV----VLGPDRAPP 175

Query: 182 PDYPRDPAQVYLWLEEAGWQIMG 204
                   +V   ++ AG  +  
Sbjct: 176 IPELPTAEEVAALMQAAGLAVER 198


>UniRef50_B5GJM0 Methyltransferase n=2 Tax=Streptomyces RepID=B5GJM0_9ACTO
          Length = 269

 Score =  141 bits (357), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 49/262 (18%), Positives = 87/262 (33%), Gaps = 32/262 (12%)

Query: 14  SRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCD 73
              +  T  G++      + L R L        RVLD GG  G  A  + + G++V + D
Sbjct: 21  DARLRDTADGRMELVRTQELLRRFL---PDAPARVLDVGGATGIHAEWLVKDGYEVTVVD 77

Query: 74  LSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVA---DPRS 130
              + +++A         S     +   A+ +    +   D +     L  +    D R 
Sbjct: 78  PVPRHVEQA---------SAVCHAVVGDARSLP-EPDETFDAVQLLGPLYHLPAEEDRRK 127

Query: 131 VLQTLWSVLRPGGVLSLMFYNAHGLLMHNM---------VAGNFDYVQAGMPKKKKRTLS 181
            L     V++PGG+++    N +  L  ++         +  +   + A       R  +
Sbjct: 128 ALAEACRVVKPGGLIAAAAINRYASLFEHVTYAHLHTDRMRASVSKILATAVHDGARGFT 187

Query: 182 PDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYL---REKHQQRDCYEALLELETRYCRQ 238
             Y      +   L  AG   +   G+      L    E+       E L+       R 
Sbjct: 188 LAYFHRADGLAAELSGAGLTDVQVFGIEGPAWSLVKAAEQQPGSGPTEDLIASALEAARM 247

Query: 239 -EPYITL---GRYIHVTARKPQ 256
            EPY  L     ++    R PQ
Sbjct: 248 AEPYPELLAASSHLLAVGRAPQ 269


>UniRef50_B8G0Y2 Methyltransferase type 11 n=1 Tax=Desulfitobacterium hafniense
           DCB-2 RepID=B8G0Y2_DESHD
          Length = 257

 Score =  141 bits (356), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 42/195 (21%), Positives = 73/195 (37%), Gaps = 12/195 (6%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
           + +   A+ ++  I     G+L +   W DL  ++        +VLD G G G  A+ M 
Sbjct: 11  KRWSFCADGYNAIIQNEFSGELSKK--WSDL--LIGNAPCPAGKVLDVGTGPGFFALLMG 66

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
             G  V   D S +MI+ A   A+  G+  + +F    +  +    +   D I+   V  
Sbjct: 67  SMGWDVHGIDCSEKMIETAVANAQKAGI--DAEFSVMDSHSL-DFPDNTFDYIVGRNVTW 123

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPD 183
            + +P    +    VL+PGG L  +  N H  L  +              ++K  T    
Sbjct: 124 ILYEPEKAFKEWLRVLKPGGRLLYLDGNWHYTLNEDW--NAARKADEAEYREKYGTPPNS 181

Query: 184 YP---RDPAQVYLWL 195
           Y    +   +    L
Sbjct: 182 YRGDEKTEEEFKKLL 196


>UniRef50_B0CTS7 Predicted protein n=2 Tax=Agaricales RepID=B0CTS7_LACBS
          Length = 285

 Score =  141 bits (356), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 48/270 (17%), Positives = 86/270 (31%), Gaps = 41/270 (15%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGP--------------QKLRVLD 50
           +F  ++ ++  +    +       +  Q +   L E+                + L VLD
Sbjct: 29  HFSRLSSQWWDHQGEFSFLHKMNPVRVQFIRDKLLEIAREENDDLDIQPTHVLRDLDVLD 88

Query: 51  AGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEA----KGVSDNMQFIHCAAQDVA 106
            G G G  +  +A  G +    D S   I  AK  A A       S  + + H +A+ + 
Sbjct: 89  VGCGGGLLSESVARLGARTHGVDASESNISIAKVHASADPKLSPPSPFLSYEHTSAESLL 148

Query: 107 SHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFD 166
           +      D++    VLE V +P S L T  ++++PGG L L   +   L     +    +
Sbjct: 149 TSP-KRYDVVCSMEVLEHVDNPASFLSTCATLVKPGGHLFLSTISRTPLAYALTIFLA-E 206

Query: 167 YVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYE 226
            V   +        +      P ++                +  F +Y   K +      
Sbjct: 207 DVLRKVSSGTH---TYSKFIKPNEL----------------IEFFQNYRDPKVRGLIYNP 247

Query: 227 ALLELETRYCRQEPYITLGRYIHVTARKPQ 256
            L                  Y+    RKP 
Sbjct: 248 LLARWHLAARDAWGGTD-CNYLFWV-RKPA 275


>UniRef50_D0BKF2 SmtA protein n=1 Tax=Granulicatella elegans ATCC 700633
           RepID=D0BKF2_9LACT
          Length = 258

 Score =  141 bits (356), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 36/165 (21%), Positives = 72/165 (43%), Gaps = 6/165 (3%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
             ++     +S+      +G  R+    +  +R+L     + L+VLD G G G   I + 
Sbjct: 9   HYWNHRYSGYSKVNQKELEGIQRER-WKKQFERLLPAN--KNLKVLDIGTGPGFFTIILE 65

Query: 64  ERGH-QVILCDLSAQMIDRAKQAAEAKGVSDN-MQFIHCAAQDVASHLETPVDLILFHAV 121
           E G+  ++  D+S +M++ AK+  +  G  D+ ++ I   AQ +        D+I+   +
Sbjct: 66  ELGYTNIMGIDVSEKMLEVAKENIQKYGKKDSSIELIQMDAQKL-EFKPESFDIIVSRNL 124

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFD 166
              +  P+        VL+P G L +   N +  L +  +   F+
Sbjct: 125 TWNLEKPQQAYSEWLRVLKPNGALFIFDANWYAFLQNESLEKEFE 169


>UniRef50_O18235 Protein Y57G11C.11a, confirmed by transcript evidence n=3
           Tax=Caenorhabditis RepID=O18235_CAEEL
          Length = 268

 Score =  141 bits (356), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 48/217 (22%), Positives = 87/217 (40%), Gaps = 15/217 (6%)

Query: 6   FDDIAEKFSRN--IYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
           F D++ +++     +       R  + W  +D V         R++D G G G  +I +A
Sbjct: 36  FGDLSAEWADELGPFHALHSLNRIRVPW-IVDNVRKSDQKAPPRLVDVGSGGGLLSIPLA 94

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEA-----KGVSDNMQFIHCAAQDVASHLET--PVDLI 116
             G  V   D + Q ++ A Q+  A      G+S  ++F H + +D           D +
Sbjct: 95  RSGFDVTGIDATKQAVEAANQSLTAKPLQIAGISKRLRFEHTSVEDFCQKPHNKSAYDAV 154

Query: 117 LFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKK 176
           +   ++E VAD    +  L  + RPG  L +   N   L     +    + V   +P   
Sbjct: 155 VASEIVEHVADLPGFIGCLAELARPGAPLFITTINRTWLSKLAAI-WLAENVLKIVPPGV 213

Query: 177 KRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHD 213
                 +    PA++   LE+AG ++    G+ +FH 
Sbjct: 214 HDW---EKFITPAELTSHLEKAGCRVTAVHGL-MFHP 246


>UniRef50_C9LTF9 SmtA protein n=2 Tax=Veillonellaceae RepID=C9LTF9_9FIRM
          Length = 248

 Score =  141 bits (355), Expect = 3e-32,   Method: Composition-based stats.
 Identities = 47/211 (22%), Positives = 78/211 (36%), Gaps = 11/211 (5%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
           +  +D  + KFS       +G    A   + +   L E   + LR+LD G G G  A+ +
Sbjct: 18  ESYWDARSPKFSAVRRRELEGSD-AARWQKFIASHLPE--KKPLRILDVGTGAGFFAVLL 74

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
              GH+V   D+SA MID A++   A G   +++     AQ +    +   D+++   + 
Sbjct: 75  TRMGHEVTGIDMSAGMIDEAQKNLAAFGCWADLR--KMNAQQL-DFSDESFDVVISRNLT 131

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNM-----VAGNFDYVQAGMPKKKK 177
             + D     +    VLR GG+L     +              V             K K
Sbjct: 132 WTLPDAMQAYREWRRVLRAGGMLLNFDSDYGETTFSAADAQDSVHTGICEALLIECNKIK 191

Query: 178 RTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
             L     R P      LE+ G+ +     +
Sbjct: 192 DELRVSTHRRPLWDAALLEKLGFSVQYDADI 222


>UniRef50_A1WUJ9 3-demethylubiquinone-9 3-methyltransferase n=1 Tax=Halorhodospira
           halophila SL1 RepID=A1WUJ9_HALHL
          Length = 245

 Score =  141 bits (355), Expect = 3e-32,   Method: Composition-based stats.
 Identities = 48/235 (20%), Positives = 91/235 (38%), Gaps = 15/235 (6%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGP-QKLRVLDAGGGEGQTAIKMAE 64
           FD   + +  +       +    I    L+ V A +G     R+LD G G G  A  MA 
Sbjct: 21  FDATGDWWEPDGSQ----RALHDINPIRLEWVEARLGGLAGKRILDVGAGGGLLAEAMAR 76

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLE----TPVDLILFHA 120
           +G QV+  D + Q +  AK  A    ++  + +  C  +++A         P D ++   
Sbjct: 77  QGAQVLGIDTARQALQTAKLHALEAEIT-TLDYRVCTVEELAEEARRGEIEPFDAVVCME 135

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL 180
           ++E    P SV+  + ++LR GG       N         + G  +Y+   +P+   +  
Sbjct: 136 MIEHTPRPESVVAAIATLLRDGGDACFSTINRTLRAYALAIVGA-EYILGLLPRGTHQ-- 192

Query: 181 SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRY 235
             +    P+++  W    G  +   TG+  ++ + R    +RD          + 
Sbjct: 193 -HERFVRPSELARWGRPHGLALQQVTGL-GYNPFARTAWLKRDASVNYFAHLRKA 245


>UniRef50_Q72HI4 Menaquinone biosynthesis methyltransferase ubiE n=6 Tax=Deinococci
           RepID=UBIE_THET2
          Length = 220

 Score =  141 bits (355), Expect = 3e-32,   Method: Composition-based stats.
 Identities = 42/208 (20%), Positives = 79/208 (37%), Gaps = 18/208 (8%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           F +IA ++       + G     + W+     LA +     R+LD   G G  A+ + ER
Sbjct: 2   FSEIAPRYDLLNRLLSFGA---DLRWRRRAVDLA-LEKAPKRILDLATGTGDLALMLKER 57

Query: 66  --GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
             G +V+  D +  M+  A++ AEA+G+   ++F+   A  +    +   D +       
Sbjct: 58  APGAEVVGADFAPPMLAIARRKAEARGLE--VRFLEADALALP-FPDGAFDAVTIAFGFR 114

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDY---------VQAGMPK 174
             AD    L  L+ VL PGG L ++ +         +V   +           +      
Sbjct: 115 NFADYEKALGELYRVLAPGGRLVVLEFPPPPKGAFGLVYRVYFQRVLPFLGGLISGNFGA 174

Query: 175 KKKRTLSPDYPRDPAQVYLWLEEAGWQI 202
            +    S +    P  +   +  AG+ +
Sbjct: 175 YRYLPESVEAFPAPEALKAMMAAAGFSV 202


>UniRef50_UPI0001924F25 PREDICTED: similar to coenzyme Q3 homolog, methyltransferase n=1
           Tax=Hydra magnipapillata RepID=UPI0001924F25
          Length = 235

 Score =  140 bits (354), Expect = 3e-32,   Method: Composition-based stats.
 Identities = 34/173 (19%), Positives = 71/173 (41%), Gaps = 6/173 (3%)

Query: 36  RVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNM 95
            +  E   +  +VLD G G G  +  +A  G +V+  D   + I+ AK     +    N+
Sbjct: 41  ELSKEYPLKGYKVLDVGCGGGILSEPIARLGAEVVGIDPLQENIEAAKSHLSFQPELINL 100

Query: 96  QFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGL 155
           ++     +++    +   DL++   VLE V +PR+ +    S ++PGG +     N    
Sbjct: 101 KYQCTLLEELC--AKELFDLVVVSEVLEHVNEPRTFVAYCCSHVKPGGYILFTTINRT-F 157

Query: 156 LMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
           +   +     +Y+   +P         +    P ++  +L+ +G       G+
Sbjct: 158 IASLLAKYVAEYIFRIVPINTHD---ENKFVPPYELTGYLQNSGMYKPTYLGM 207


>UniRef50_A6UGV5 Methyltransferase type 11 n=3 Tax=Rhizobiaceae RepID=A6UGV5_SINMW
          Length = 259

 Score =  140 bits (354), Expect = 4e-32,   Method: Composition-based stats.
 Identities = 35/214 (16%), Positives = 74/214 (34%), Gaps = 23/214 (10%)

Query: 5   NFDDIAEKFSRNI-YGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
            +   +E F     +   +G    A        V + +G + L+VL+   G G+    + 
Sbjct: 15  YWSKRSETFDLAFGHRIPRGPEFDA----WAAAVRSALGARPLKVLELACGTGEVTGVLL 70

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
             GH V   D S  M+  A++        D ++FI   A+      +   D ++   ++ 
Sbjct: 71  SLGHDVTALDFSETMLAVARRKHAGN---DKVRFILADAER-TMEPDGTYDAVVCRHLVW 126

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLL----MHNMVAGNFDYVQAGMPKKKK-- 177
            + +P   L     +L+PGG L +   +         + ++     + +    P      
Sbjct: 127 TLTEPEQALAEWLRLLKPGGRLLVFDGDWSKPTPLGRLASLAVAALERIIGYDPHYDGAM 186

Query: 178 --------RTLSPDYPRDPAQVYLWLEEAGWQIM 203
                     L         ++   +E AG++ +
Sbjct: 187 SERHAKIMERLPFGDGLTVERLVPLIEAAGFENI 220


>UniRef50_A5UZ15 Methyltransferase type 11 n=2 Tax=Roseiflexus RepID=A5UZ15_ROSS1
          Length = 282

 Score =  140 bits (354), Expect = 4e-32,   Method: Composition-based stats.
 Identities = 50/276 (18%), Positives = 92/276 (33%), Gaps = 36/276 (13%)

Query: 5   NFDDIAEKF-----SRNIYGTTKGQLRQAILWQDLDRVLAEM-----GPQKLRVLDAGGG 54
            +D +   +          G   G    +   +  DR+   +           +LD G G
Sbjct: 17  YYDLMGPFYATLWGDNFHVGYWTGPDDTSSNVEAQDRLTDLLINKVNLAPGQTLLDIGCG 76

Query: 55  EGQTAIKMAER-GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPV 113
            G+ A++++++ G  V+   +SA  + RA   AE  GV+D ++F    A  +    +   
Sbjct: 77  VGRPAVRLSQQTGAAVVGITVSADQVARATALAERSGVADRVRFQRADAMALP-FDDASF 135

Query: 114 DLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMP 173
           D +     L  + D   VL+ +W VLRPGG   L                    + A   
Sbjct: 136 DAVWAFESLLHMPDRAHVLREVWRVLRPGGRFILTD------------VTEERPLSAEQR 183

Query: 174 KKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV-----RVFHDYLREKHQQRDCYEAL 228
                +          +  + +   G+ +     +     R          ++R+    L
Sbjct: 184 ALLYGSFLLRSLETIERYPMLVTATGFIVDDVIDISAQTKRTLQYVSDALMEKRETIRTL 243

Query: 229 LELETRYCRQEPYITLGR-------YIHVTARKPQS 257
              E     ++ +  L         YI + A KP S
Sbjct: 244 YGAELLATLEQVWPILATIQRDYLGYIVLAAHKPLS 279


>UniRef50_C1B334 Putative uncharacterized protein n=2 Tax=Bacteria
           RepID=C1B334_RHOOB
          Length = 323

 Score =  140 bits (353), Expect = 5e-32,   Method: Composition-based stats.
 Identities = 39/256 (15%), Positives = 78/256 (30%), Gaps = 28/256 (10%)

Query: 4   RNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
            ++D  A  +  +I            L++    +         RVLDAG G G  +  + 
Sbjct: 5   NDYDRYASAYDADIEDNV-----YNALYERPATLALVGDVAGRRVLDAGCGSGVLSQALV 59

Query: 64  ERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLE 123
             G  V   D+SA ++  A+       +  ++  I            +  D+++   V+ 
Sbjct: 60  AAGAAVTGVDVSANLLAIARNR-----LGPDVSLIRADLNRQLPLASSTFDVVVASLVMH 114

Query: 124 WVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPD 183
           ++ D    L     VL PGG + L  ++       +      D  +      K     P 
Sbjct: 115 YLHDWSGPLSEFHRVLAPGGCVVLSTHHPFVDFRPSGQGDYLDTFEFTEEWVKSGETFPM 174

Query: 184 YPRDP--AQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPY 241
                    ++     AG+ +   +  R       +   +    E   +L          
Sbjct: 175 RFWHRPLHAMFDAFTTAGFTVERVSEPR------PDAAVRDRSPELFEQLNRE------- 221

Query: 242 ITLGRYIHVTARKPQS 257
                +I    R+  +
Sbjct: 222 ---APFIFFVLRRGAT 234


>UniRef50_Q11GJ5 Methyltransferase type 11 n=2 Tax=Alphaproteobacteria
           RepID=Q11GJ5_MESSB
          Length = 258

 Score =  140 bits (353), Expect = 5e-32,   Method: Composition-based stats.
 Identities = 45/235 (19%), Positives = 90/235 (38%), Gaps = 22/235 (9%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           F   AE + ++     +G+  Q+++ +         G    RVLD G G G     +A  
Sbjct: 15  FGSRAEAYLKSAV-HAQGEDLQSLVARM-------AGKSGARVLDLGCGGGHVTFHIAPL 66

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV 125
             +V+  DLS +M++   + A  +G++ N+      A+ +    +   D +L        
Sbjct: 67  VREVVAYDLSPEMLEVVGRTARERGLA-NIATARGVAESLPFEAD-SFDAVLSRFSAHHW 124

Query: 126 ADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYP 185
            D  + L+    VL+PGG + ++     G+ + +      + +         R  S    
Sbjct: 125 RDLDAGLREAARVLKPGGSVIILDTVTAGVPIIDTFFQAIELL---------RDCSHVRN 175

Query: 186 RDPAQVYLWLEEAGWQIMGKTGVRV---FHDYLREKHQQRDCYEALLELETRYCR 237
              A+    L  AG  +   +  R+   F  ++   +  +   EA+  L+T    
Sbjct: 176 YSRAEWEAALARAGLPVRSSSRFRLRLEFKSWVERMNTPKIQVEAIRALQTSVSE 230


>UniRef50_A9CF50 Methyltransferase n=16 Tax=Alphaproteobacteria RepID=A9CF50_AGRT5
          Length = 274

 Score =  140 bits (353), Expect = 5e-32,   Method: Composition-based stats.
 Identities = 40/228 (17%), Positives = 80/228 (35%), Gaps = 27/228 (11%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
            +   A  F  +       +  +A     + + L     +  + LD   G G  +  M +
Sbjct: 20  YWSGRAATFDLSPGHEIFSEDERAAWHALILKHLGR--GEGRKALDLASGTGVISHLMDD 77

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
            G QV   D S  M+  A++ A+++G   N++F    A++     +   D+I+   ++  
Sbjct: 78  LGFQVTGMDWSETMLGLAREKAKSRG--RNIRFFVGDAEN-TMEPDESADVIITRHLVWT 134

Query: 125 VADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDY 184
           + DP++     + VL+PGG L ++  +         +          +     +   P  
Sbjct: 135 LVDPQASFAEWFRVLKPGGKLLIVDGDFVNTGWRERLVKKLAVSLESI--GLVKADQPHK 192

Query: 185 PRDPA-------------------QVYLWLEEAGWQIMGK-TGVRVFH 212
           P DP                     V   L   G++ +     +R  H
Sbjct: 193 PADPENTFNSILSRVYFSKGARAGDVATMLGATGFEPVSVDQELRAIH 240


>UniRef50_B8FPB3 Methyltransferase type 11 n=4 Tax=Clostridiales RepID=B8FPB3_DESHD
          Length = 209

 Score =  140 bits (353), Expect = 5e-32,   Method: Composition-based stats.
 Identities = 40/214 (18%), Positives = 88/214 (41%), Gaps = 19/214 (8%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIK 61
             + +D  +  +   I    K        ++++  +++E+    +RVL+   G G  A+ 
Sbjct: 4   NKKFWDRYSGLYDFEINRFNK------AAYEEMYSLMSEVLRADMRVLEVATGTGLMALG 57

Query: 62  MAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
           +A+   QV   D S +MI+ AK+         N++F    A  ++       D ++    
Sbjct: 58  IAKFVRQVEATDFSPKMIETAKKKIA----PANVRFSLEDATALS-FANDSFDAVIISNA 112

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLS 181
           L  + DP + L ++  VL+P G+L    +  HG L ++    N   ++    +   +   
Sbjct: 113 LHIMPDPEATLASIRRVLKPDGLLIAPTFA-HGHLKNSTWNLNARILKLIGFETYSKW-- 169

Query: 182 PDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYL 215
                 P +   ++E+ G+ +  +  +R     +
Sbjct: 170 -----TPEEYTGFIEKNGFSVGRRKVLRAAFPLV 198


>UniRef50_Q9RYC4 Methyltransferase, putative n=2 Tax=Deinococcus RepID=Q9RYC4_DEIRA
          Length = 269

 Score =  140 bits (353), Expect = 5e-32,   Method: Composition-based stats.
 Identities = 49/233 (21%), Positives = 84/233 (36%), Gaps = 18/233 (7%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIK 61
             R FD IA  +    +          +    L    A   P   RVLD   G G  A+ 
Sbjct: 11  NARQFDRIAADYDALGF----------LTQAALALAAALDVPPTGRVLDVATGTGTVALT 60

Query: 62  MAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
           +A +  +V+  D++  MI++A+Q A  +    N+QF+   A  +    +   D+++  A 
Sbjct: 61  LAPKVAEVMGTDIAPAMIEQARQRAAGR---SNVQFVLAEATALT-FADQSFDVVVCGAG 116

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLS 181
           L +V D  + L+    VLRPGG +    +      +   + G +    AG    K     
Sbjct: 117 LFFVPDMVAALREWRRVLRPGGEVVFSAFGRG---LLGPLPGLWRERLAGE-GVKPGAPP 172

Query: 182 PDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETR 234
                        L +AG+  +      + +       +  D    L  L   
Sbjct: 173 LGRIGTVEAAKDLLIQAGFAEVTAELTPLPYTLATPADRWADIRAGLEGLPLA 225


>UniRef50_C6PBK3 Methyltransferase type 11 n=1 Tax=Thermoanaerobacterium
           thermosaccharolyticum DSM 571 RepID=C6PBK3_CLOTS
          Length = 211

 Score =  140 bits (353), Expect = 5e-32,   Method: Composition-based stats.
 Identities = 39/196 (19%), Positives = 81/196 (41%), Gaps = 14/196 (7%)

Query: 5   NFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAE 64
            FD IA ++           +R   + +             L V D G G G  A+++++
Sbjct: 6   YFDSIAGEWDEIRKKYFDDDIRNIAIERS-----NIKNKGGLIVADIGTGSGFMALELSK 60

Query: 65  RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
              +V+  D+S +M+  AKQ AE  G+ +N+ F+  + + +    +  +D++  + VL  
Sbjct: 61  YAREVVGIDVSDEMLKYAKQTAENAGI-NNIIFLKGSMEQIPIIDD-SIDVVFSNMVLHH 118

Query: 125 VADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDY 184
           V +P   +  +  +L+PGG+L +     H           +D       +  ++ L    
Sbjct: 119 VENPFKGIMEIHRILKPGGMLIITDVMKHSSEWAR--FEMYDRWLGFNLEDIEKWLIHSN 176

Query: 185 PRDPAQVYLWLEEAGW 200
            ++       ++E G 
Sbjct: 177 FKEI-----LVKETGL 187


>UniRef50_A4FIY5 Ubiquinone/menaquinone biosynthesis methyltransferase n=1
           Tax=Saccharopolyspora erythraea NRRL 2338
           RepID=A4FIY5_SACEN
          Length = 245

 Score =  140 bits (353), Expect = 5e-32,   Method: Composition-based stats.
 Identities = 54/224 (24%), Positives = 82/224 (36%), Gaps = 18/224 (8%)

Query: 4   RNFDDIAEKFSRNIYGTT-KGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
           RN+D  A  ++R     +   +       + +   L   G   L VLD G G G  +  +
Sbjct: 13  RNWDRRARDYNRFYRRFSADRRDAWRTACEKIVPALRPGGAGPLDVLDVGTGTGFLSTLL 72

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
           AE GH+V   D SA M+  A++ AE +GV  ++ F  C A DV     +  DL+    VL
Sbjct: 73  AELGHRVTAVDPSATMLGYAREEAERRGV--DVSFRECGAHDVEDLA-STFDLVTARYVL 129

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGL---------LMHNMVAGNFDYVQAGMP 173
             +  P         VLRPGG + +     H            +       F +      
Sbjct: 130 WTLPAPVRATAAWSRVLRPGGAVLIADSTWHTWRGDGRRLLASLRPGGDHGFAWRLLRDY 189

Query: 174 KKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLRE 217
            +  R         P +    L   G++   +     F D L E
Sbjct: 190 VRIGRATPNWKGLTPQRAQAILAAGGFRRGER-----FDDLLPE 228


>UniRef50_C8XH01 Methyltransferase type 11 n=1 Tax=Nakamurella multipartita DSM
           44233 RepID=C8XH01_NAKMY
          Length = 262

 Score =  140 bits (353), Expect = 5e-32,   Method: Composition-based stats.
 Identities = 56/224 (25%), Positives = 96/224 (42%), Gaps = 6/224 (2%)

Query: 39  AEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFI 98
                  +RVLD GGG G  A+ +A  G  V + D S   +    + A+  GV+D +  +
Sbjct: 36  EPGTLAAVRVLDVGGGSGTRAVPLAVLGCSVTVVDASVNSLAILHRRAQDAGVADRVVGV 95

Query: 99  HCAAQDV-ASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLM 157
              A  + A      +DL+L H +LE V DP +V+  +   +RPGG +S++     G ++
Sbjct: 96  QADADRLEAIAAPASIDLVLCHHLLEAVDDPAAVMGAVVRTVRPGGYVSILVAGRLGAVL 155

Query: 158 HNMVAGNFDYVQAGMPKKKKRTLSPD---YPRDPAQVYLWLEEAGWQIMGKTGVRVFHDY 214
              +AG F+  +  +     R+ + D      D   V   ++  G Q+   +GV V    
Sbjct: 156 GQTMAGRFEAARELLTGPDGRSGAADTLRRRFDVPGVRALVDSVGLQVESVSGVGVLVGL 215

Query: 215 LRE--KHQQRDCYEALLELETRYCRQEPYITLGRYIHVTARKPQ 256
           +    +         L  LE    +    + +   +HV AR+P 
Sbjct: 216 VSGVIRQAGPGGEADLAALEAAAGQHPELLHIAADLHVVARRPD 259


>UniRef50_D1YX02 Methyltransferase n=1 Tax=Methanocella paludicola SANAE
           RepID=D1YX02_METPS
          Length = 271

 Score =  140 bits (353), Expect = 5e-32,   Method: Composition-based stats.
 Identities = 44/241 (18%), Positives = 89/241 (36%), Gaps = 29/241 (12%)

Query: 1   MQDRNFD--DIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMG-PQKLRVLDAGGGEGQ 57
           M    +D  ++AE + R             + ++   R++ +M   +   VLD G G G+
Sbjct: 1   MSSAAWDGQELAELYDRIS----------DLQYESGRRLVEKMQVKKGDNVLDVGCGTGR 50

Query: 58  TAIKMAERGH---QVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVD 114
            A  +         V   DLS   I  A+     K    N+  +    +D++   +   D
Sbjct: 51  LAFYIVGTVGPLGSVTGIDLSPHRIKVAEAKLNEKK-YPNVCLMVGRGEDLSQFPDESFD 109

Query: 115 LILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPK 174
            + + +V  WV D ++  +  + VL+ GG + +   +         +   F+ + +  P 
Sbjct: 110 RVCYSSVFHWVDDKKAAAEEAYRVLKHGGNIGITTVDKSHP---FAMRKVFEKLFSEEPY 166

Query: 175 KKKRTLSPD--YPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELE 232
             K  L        D  Q+   L +A ++ +         DY+ +  +     E +  +E
Sbjct: 167 AGKVDLMAQMSMLVDRNQLEQLLYDARFRRIDV-------DYIDKTVRYSSAEELINLME 219

Query: 233 T 233
            
Sbjct: 220 A 220


>UniRef50_B3E0R3 Methylase involved in ubiquinone/menaquinone biosynthesis n=1
           Tax=Methylacidiphilum infernorum V4 RepID=B3E0R3_METI4
          Length = 287

 Score =  139 bits (352), Expect = 6e-32,   Method: Composition-based stats.
 Identities = 50/228 (21%), Positives = 96/228 (42%), Gaps = 24/228 (10%)

Query: 6   FD--DIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMA 63
           FD   +A ++ R +      Q R+ +    + R          RVLD G G G+ A  +A
Sbjct: 28  FDSLQLAAEYDR-LSDPQFNQGRELVSLLKIKRA--------DRVLDIGCGTGRLAAYVA 78

Query: 64  E---RGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA 120
               +  +VI  D S   I  A++  ++     N+ F     ++++   +   D++  ++
Sbjct: 79  GITGKEGKVIGIDPSPFRIAIARRREKS-----NLLFKVAGTEELSLFEDNSFDVVYLNS 133

Query: 121 VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAH-GLLMHNMVAGNFDYVQAGMPKKKKRT 179
           V  W+ D    +  ++ VL+PGG L +     H   L+ +++  +   V   +PK+    
Sbjct: 134 VFHWIGDRAQAMVEIYRVLKPGGKLGIAMGAKHQDSLLVSILRRSAQSVLGYIPKEFALN 193

Query: 180 LSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEA 227
              +Y R+  +      E+G++I      R + D  R   +    YEA
Sbjct: 194 ---EYQREADEALELSRESGFKIQEIK-TRHYVDLFRSGEECIRFYEA 237


>UniRef50_A7Z1X4 Putative uncharacterized protein n=1 Tax=Bacillus amyloliquefaciens
           FZB42 RepID=A7Z1X4_BACA2
          Length = 260

 Score =  139 bits (352), Expect = 6e-32,   Method: Composition-based stats.
 Identities = 51/249 (20%), Positives = 90/249 (36%), Gaps = 16/249 (6%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQK-LRVLDAGGGEGQTA 59
           M+D        +F++N           A   +DL  +++  G +K + VLD   G G TA
Sbjct: 1   MEDSIKQQAQRQFAKNAAKYVTSPGHAAG--EDLAYLVSASGAEKHMDVLDIATGGGHTA 58

Query: 60  IKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFH 119
             +A     VI  DL+ +M+  A+      G + N+ F    A+ +    +   D++   
Sbjct: 59  NALAPLVRSVIAYDLTEEMLAAAEAFITGNGWT-NVSFEKGDAEKMP-FSDAAFDIVTCR 116

Query: 120 AVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRT 179
                  D R+ +   + V++PGG L L+          N  A   +Y       +KKR 
Sbjct: 117 IAAHHFPDVRAFVHEAFRVVKPGGRLLLID---------NTAAEKDEYDHFYNDIEKKRD 167

Query: 180 LSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQE 239
            S        +   +LE AG++I     V     +      +R                +
Sbjct: 168 QSHFRAWKKTEWLRFLETAGFRIESA--VCFLKPFQFTVWCERAGLTEEKAALLEKQMLD 225

Query: 240 PYITLGRYI 248
               + R+ 
Sbjct: 226 APRDIQRFF 234


>UniRef50_Q73R34 Methlytransferase, UbiE/COQ5 family n=1 Tax=Treponema denticola
           RepID=Q73R34_TREDE
          Length = 250

 Score =  139 bits (352), Expect = 6e-32,   Method: Composition-based stats.
 Identities = 38/178 (21%), Positives = 69/178 (38%), Gaps = 16/178 (8%)

Query: 44  QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQ 103
           +  +VLDAG G G  AI +A+ G +V   D S  M++  K+ AE  G+SD + F+   A 
Sbjct: 44  KGKKVLDAGCGTGFLAILLAQDGWEVTAIDSSEAMLEEGKKTAEELGLSDKITFLLKDAH 103

Query: 104 DVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAG 163
                 E   D ++          P +V +    +L+PGG++  +  N    + +     
Sbjct: 104 S-TDFPEHLFDAVVSRHASWLFTAPETVYKEWKRILKPGGIMLNIDANWLKPIWNTDEFE 162

Query: 164 NFDYVQAGMPKKKK---------------RTLSPDYPRDPAQVYLWLEEAGWQIMGKT 206
            F   +A + K+                 +     Y   P      L++  ++ +   
Sbjct: 163 KFKSYEAELVKQYGEFRDYYHDEQMINILKKFPLAYINRPEWDEKMLKKIDFKEIASR 220


>UniRef50_A9GFV3 Trans-aconitate 2-methyltransferase n=1 Tax=Sorangium cellulosum
           'So ce 56' RepID=A9GFV3_SORC5
          Length = 271

 Score =  139 bits (352), Expect = 6e-32,   Method: Composition-based stats.
 Identities = 49/270 (18%), Positives = 89/270 (32%), Gaps = 32/270 (11%)

Query: 13  FSRNIYGTTKGQLRQAILWQDLDRVLAEMG-PQKLRVLDAGGGEGQTAIKMAERGH---Q 68
           F                 ++   R++AE+G      VLD G G G  A  +A       +
Sbjct: 8   FDTPQLAQDYELRSADRQFRHGKRLIAELGVRAGDHVLDVGSGTGLLAEHVAGLVGLTGK 67

Query: 69  VILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADP 128
           V+  D     ++ A+Q A+A     N+ F    A  +        D++  +AV  W+ + 
Sbjct: 68  VLGIDPLPLRVEIAQQKAKA-----NLSFQVGNAYALDGLPSGSFDVVYLNAVFHWLPEK 122

Query: 129 RSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDP 188
              L+ +  +L+PGG + L             +       +      + R  +P +    
Sbjct: 123 TEPLRQIHRLLKPGGRIGLTTGAKDHPNRLQAIKREVLSREPYASYPESRDGTPHW-VTA 181

Query: 189 AQVYLWLEEAGWQIMGKTGVRVFHD---------------------YLREKHQQRDCYEA 227
            ++   L  AG+ +         H                      +L E  + +   + 
Sbjct: 182 VELAGLLGGAGFTVQKIEAQENVHHQPDGRAAIAFSQASSFGNFLGHLPESLRSQAIEDI 241

Query: 228 LLELETRYCRQEPYITLGRYIHVTARKPQS 257
             ELE  +   E     G+ +   A KP S
Sbjct: 242 QRELE-AFRTPEGIRLEGKRLFAIAHKPAS 270


>UniRef50_A9GFL2 Ubiquinone/menaquinone biosynthesis methyltransferase n=3
           Tax=Bacteria RepID=A9GFL2_SORC5
          Length = 243

 Score =  139 bits (352), Expect = 7e-32,   Method: Composition-based stats.
 Identities = 45/210 (21%), Positives = 78/210 (37%), Gaps = 14/210 (6%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           FD IAE++       + G       W+       E+ P    VLD   G    AI +A  
Sbjct: 22  FDGIAERYDLLNRVISLG---LDQGWRRRAVRSLELSP-GATVLDLATGTADLAIAIARA 77

Query: 66  G-HQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEW 124
              +VI  D S  M+   ++  EA G++  ++     AQ +    +  VD I     +  
Sbjct: 78  HEVKVIGVDPSQGMLGVGRRKVEAAGLAGRVELEVGDAQQL-QLGDASVDAISMAFGIRN 136

Query: 125 VADPRSVLQTLWSVLRPGGVLSLMFYNAH-----GLLMHNMVAGNFDYVQAGM---PKKK 176
           V D    L+ +  V RPGG ++++  +       G L    +     YV   +    + +
Sbjct: 137 VPDRARALREMARVTRPGGRIAILELSEPRSGLMGKLARFHIHTVVPYVGGAISGKDEYR 196

Query: 177 KRTLSPDYPRDPAQVYLWLEEAGWQIMGKT 206
               S      P +    +  AG +++   
Sbjct: 197 YLQDSIARFPPPDEFAELMRGAGLRVLRVE 226


>UniRef50_B8H5N0 Methyltransferase n=3 Tax=Caulobacter RepID=B8H5N0_CAUCN
          Length = 292

 Score =  139 bits (352), Expect = 7e-32,   Method: Composition-based stats.
 Identities = 46/245 (18%), Positives = 88/245 (35%), Gaps = 18/245 (7%)

Query: 8   DIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMG--PQKLRVLDAGGGEGQTAIKMAER 65
           D++  + R      + Q     L+Q + + + +         VLD G G G T  + A R
Sbjct: 23  DMSAYWDRAGRVWVEQQALLDRLFQPIAQAVVDRADLRAGEAVLDVGCGSGATTFEAAWR 82

Query: 66  GH---QVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
                + +  D+S  +++ A++ A  +G+   + F+   AQ          D I+    +
Sbjct: 83  VGPQGRAVGADISGALLELARRRAGEQGLEG-VDFVQADAQTHDF--GAGFDAIVSRFGV 139

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFY-NAHGLLMHNMVAGNFDYVQAGMPKKKKRTLS 181
            +  DP +    L   LRPGG L+   +       M  +       +    P+ ++    
Sbjct: 140 MFFPDPVAAFANLRRALRPGGRLAFACWRGPEDNPMAQVPLDAAAPILPETPRFERNAPG 199

Query: 182 PDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEPY 241
                DP +V   L EAGW+ +                     ++ L+ +  R     P 
Sbjct: 200 RFGFADPERVRSILAEAGWRDIAIA---------PLDDPTPISFDELMTMSLRVGPLNPI 250

Query: 242 ITLGR 246
           ++   
Sbjct: 251 LSNAE 255


>UniRef50_A8LNN9 3-demethylubiquinone-9 3-methyltransferase n=8 Tax=Rhodobacteraceae
           RepID=A8LNN9_DINSH
          Length = 232

 Score =  139 bits (351), Expect = 8e-32,   Method: Composition-based stats.
 Identities = 50/203 (24%), Positives = 87/203 (42%), Gaps = 9/203 (4%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           +D  A+++  +       +  + ++   LD     +  Q  +VLD G   G  A  +  R
Sbjct: 8   YDSEADRWWSD--DVRWVRTLKNMVPGRLDYFDRFIDWQGKQVLDLGCAGGFMAEALEAR 65

Query: 66  GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWV 125
           G +V   D +A+ I  A+  A A G   ++++   A +D+  +     D ++   VLE V
Sbjct: 66  GARVTGIDPAAKAIAAARSHAAATG--RDIRYDIGAGEDLP-YGTGCFDAVVCVDVLEHV 122

Query: 126 ADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYP 185
            D   V+  +  VL+PGG+      N +  L    V    + V   +PK       PD  
Sbjct: 123 RDLDQVVAEVARVLKPGGLFLFDTINRN-PLSRLAVITLAEDVLGLLPKGTHD---PDMF 178

Query: 186 RDPAQVYLWLEEAGWQIMGKTGV 208
             PA++   LE  G+ +   TG+
Sbjct: 179 IKPAELRAALEAQGFAVGKFTGL 201


>UniRef50_UPI0001758A2F PREDICTED: similar to hexaprenyldihydroxybenzoate methyltransferase
           n=1 Tax=Tribolium castaneum RepID=UPI0001758A2F
          Length = 411

 Score =  139 bits (351), Expect = 8e-32,   Method: Composition-based stats.
 Identities = 39/180 (21%), Positives = 78/180 (43%), Gaps = 12/180 (6%)

Query: 41  MGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHC 100
           +  + L +L+ G G G     +A  G  V   D +  +I+RAK  ++   +  N+++I  
Sbjct: 223 LPIKGLSILEVGCGGGILTEPLARIGADVTGLDANPDLIERAKLHSKNDNL--NIKYICS 280

Query: 101 AAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAH--GLLMH 158
             +  A       D I+   +LE V   +  L+     ++PGG + +   N      L  
Sbjct: 281 PVEKYAVVNVEKHDAIVASEILEHVTKKKEFLKHCVKCMKPGGSIFITTINKTVVAKLFG 340

Query: 159 NMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREK 218
            ++A +F  +   +P+   +    D   +P ++   LEE G + +   G+  F++ L  +
Sbjct: 341 VVIAESFFKL---LPEGTHQY---DKFIEPHKLERILEELGCKTILTHGI--FYNVLTNE 392


>UniRef50_C4Q545 Hexaprenyldihydroxybenzoate methyltransferase, putative n=1
           Tax=Schistosoma mansoni RepID=C4Q545_SCHMA
          Length = 286

 Score =  139 bits (351), Expect = 8e-32,   Method: Composition-based stats.
 Identities = 42/225 (18%), Positives = 83/225 (36%), Gaps = 22/225 (9%)

Query: 2   QDRNFDDIAEKFSRNIYG----TTKGQLRQAILWQDLDRVLA-------EMGPQKLRVLD 50
           +D NF   A+ +           T  +LR   +   L  +          +  +  ++LD
Sbjct: 38  EDANFKRFAQHWWDYDGDLQPLHTMNRLRVPFIQNGLCPITLLSTMDSVYLPLKGKKILD 97

Query: 51  AGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVS-------DNMQFIHCAAQ 103
            G G G  A  ++  G +V+  DL  + I  A++  EA               +   + Q
Sbjct: 98  VGCGGGILAEALSMLGAEVLGIDLIEEGIKIAQEHVEATSYRWADHPDLYKPTYKLTSIQ 157

Query: 104 DVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAG 163
            +        D ++   V E V D   +L  L   L+  G+L +   N     +   + G
Sbjct: 158 SITQEYPCQFDAVVASEVFEHVTDWEDMLNNLKQCLKLDGMLFVTTINHTAASLLLGI-G 216

Query: 164 NFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGV 208
             +YV   +P+        +   +P+++ +   + G+Q    +G+
Sbjct: 217 VAEYVARIVPRGTHNW---NKFIEPSRLQIACIKRGFQPRQLSGM 258


>UniRef50_UPI0001B5455F methyltransferase type 11 n=1 Tax=Streptomyces sp. AA4
           RepID=UPI0001B5455F
          Length = 290

 Score =  139 bits (351), Expect = 9e-32,   Method: Composition-based stats.
 Identities = 56/208 (26%), Positives = 86/208 (41%), Gaps = 13/208 (6%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIK 61
           Q  N+D I+E +         G    + L  +L  V         RVLD G G G  A+ 
Sbjct: 15  QRENWDAISEGWEACRAEFETGGAPVSALLLELGGV-----RPGHRVLDVGTGTGDPALA 69

Query: 62  MAERGH---QVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILF 118
            A       +V   DL+  MI+RA+  A + G   N+ F    A+ +        D++L 
Sbjct: 70  AAAAVGPRGRVTGIDLAPGMIERARARAASGG---NVAFEVGDAESL-DRPAASFDVVLS 125

Query: 119 HAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAG-MPKKKK 177
              L +V D  + L++L  +L PGGVL+   + A G L      G     +   +P  ++
Sbjct: 126 RWGLMFVVDRAATLRSLARMLAPGGVLAAATWAAPGSLAPMTSLGFGVLARRLELPPPRE 185

Query: 178 RTLSPDYPRDPAQVYLWLEEAGWQIMGK 205
              SP    DP  +   L EAG+  +  
Sbjct: 186 GAPSPFSMGDPEVLREELAEAGFGQIEI 213


>UniRef50_Q74LY0 Menaquinone biosynthesis methyltransferase ubiE n=26
           Tax=Lactobacillus RepID=UBIE_LACJO
          Length = 244

 Score =  139 bits (351), Expect = 9e-32,   Method: Composition-based stats.
 Identities = 36/212 (16%), Positives = 76/212 (35%), Gaps = 16/212 (7%)

Query: 6   FDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER 65
           F  +A  + +     + G       W+                LD   G G   I +A++
Sbjct: 20  FTRVAPHYDQMNNLISLG---TQNGWRKKFFK-KLKVKAGDFALDLCCGTGDLTIALAKQ 75

Query: 66  GH---QVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
                 VI  D + +M+D A +    + +   +Q     A  +  + +   D++     L
Sbjct: 76  VGPSGNVIGLDFNQKMLDLADKKIRGQNLQKEIQLKQGDAMHLP-YTDQSFDIVTIGFGL 134

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAH-------GLLMHNMVAGNFDYVQAG-MPK 174
             V D   VL+ ++ VL+P G + ++  +         G   +  +  NF  +    +  
Sbjct: 135 RNVPDADQVLKEIYRVLKPDGKVGILETSQPTNPIIKLGWESYFKLFPNFAKLLGANVDD 194

Query: 175 KKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKT 206
            K  + +        ++   LE+ G++ +  T
Sbjct: 195 YKYLSHTTAKFISATRLKEMLEQDGFKNVIIT 226


>UniRef50_Q9EYI2 SnogM n=1 Tax=Streptomyces nogalater RepID=Q9EYI2_STRNO
          Length = 278

 Score =  139 bits (351), Expect = 9e-32,   Method: Composition-based stats.
 Identities = 39/197 (19%), Positives = 67/197 (34%), Gaps = 13/197 (6%)

Query: 13  FSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAER-GHQVIL 71
           +          +  Q +     +R+         RVLD G G G  A+++A   G +V+ 
Sbjct: 35  WDSLPADAGMDRASQRLTEMMTERI---EVGPGQRVLDIGCGTGAPAVQLARATGAEVVG 91

Query: 72  CDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSV 131
             +S + +  A   AE +GV++ + F    A           D + F   +  + D  + 
Sbjct: 92  ITISPEQVRLATAHAEREGVAERVTFRCADASAELPFPADSFDAVWFFESIFHLPDRLTA 151

Query: 132 LQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYPRDPAQV 191
           L+    VLRPGG L+L     H          + D         +   LS          
Sbjct: 152 LRRAAEVLRPGGRLALTDV-LHNDETSPAAQESLDEHAYTPLVGEPMRLS--------DY 202

Query: 192 YLWLEEAGWQIMGKTGV 208
              L +A    +    +
Sbjct: 203 PPLLRQARLVPVECRDI 219


>UniRef50_C5A2C6 SAM-dependent methyltransferase, ubiE/COQ5 family n=7
           Tax=Thermococcaceae RepID=C5A2C6_THEGJ
          Length = 228

 Score =  139 bits (350), Expect = 1e-31,   Method: Composition-based stats.
 Identities = 44/175 (25%), Positives = 77/175 (44%), Gaps = 8/175 (4%)

Query: 11  EKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVI 70
           E +S     +           ++L+ +L +   +K +VLD G G G  +  + + G  V+
Sbjct: 5   EYYSAFKAYSDIYSDEYRKRIENLEPLLMKFMKEKGKVLDLGCGAGGFSFLLEDLGFTVV 64

Query: 71  LCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVA--DP 128
             D S  M+  A+  A+ KG    ++FI   A+++    +   D +LF   L      D 
Sbjct: 65  GVDNSEYMLSLARGFAKEKG--SKVEFIKADARELP-FEDNTFDYVLFIDNLVHFEPLDL 121

Query: 129 RSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNM---VAGNFDYVQAGMPKKKKRTL 180
               + +  VL+PGG L L F +   LL   M   V G   ++   +P K ++T+
Sbjct: 122 GKAFREMARVLKPGGKLILQFTDLRALLPVLMNGQVIGAEYWISKVLPDKDEKTV 176


>UniRef50_Q2FUA7 UbiE/COQ5 methyltransferase n=1 Tax=Methanospirillum hungatei JF-1
           RepID=Q2FUA7_METHJ
          Length = 237

 Score =  139 bits (350), Expect = 1e-31,   Method: Composition-based stats.
 Identities = 41/259 (15%), Positives = 94/259 (36%), Gaps = 25/259 (9%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI 60
           MQ    DDIA+ + +      +G++    +   +   L ++ P    +LD G G G    
Sbjct: 1   MQSHY-DDIADVYDQRYDHRERGRIYYDHIAGAV---LGKINPSG-HLLDIGCGTGLFLE 55

Query: 61  KMAERG--HQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILF 118
           +  + G        D+S  MI +A++         ++ ++   A+ +    +   D I  
Sbjct: 56  RYLKEGTDRTATGIDISPGMIKKARER------YPDLPYVVGNAELLPFESD-SFDSISS 108

Query: 119 HAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKR 178
                ++ +P   L   + VL PGG L++     +  +  + +   +        ++   
Sbjct: 109 LLAFSYLQNPGQSLSDCYRVLVPGGRLAVCTLGKN--IFTSSLPALYSIGAKMKIRRVGV 166

Query: 179 TLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFH-DYLREKHQQRDCYEALLELETRYCR 237
               ++     ++Y  L++AG++ +        H +            E+ +E       
Sbjct: 167 GSFAEHYYSAKEMYDLLDKAGFEEIEIFKCSFAHFNLAGPLFMIAKKVESFIE------- 219

Query: 238 QEPYITLGRYIHVTARKPQ 256
            +    L   +    +KP+
Sbjct: 220 -DNIPYLAYNLIAAGKKPE 237


>UniRef50_B8G1N6 Methyltransferase type 11 n=1 Tax=Desulfitobacterium hafniense
           DCB-2 RepID=B8G1N6_DESHD
          Length = 252

 Score =  139 bits (350), Expect = 1e-31,   Method: Composition-based stats.
 Identities = 40/198 (20%), Positives = 82/198 (41%), Gaps = 4/198 (2%)

Query: 3   DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKM 62
           +  +   AE F+         +  +  LW+ + +   +   +KL +LD G G G   I +
Sbjct: 8   NDYWSTQAEAFTEISVDELTSE--KNALWKSILKPFVQ-TDRKLEILDVGCGAGFFEIFL 64

Query: 63  AERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVL 122
           +  GH V   D + +M+  A++  E  G  +  + +   AQ++A   ++  D+++   + 
Sbjct: 65  SCLGHHVTAVDFNGKMLAEARKNIEKLGRPELTKLMQMDAQNLA-FQDSVFDIVISRNMT 123

Query: 123 EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLSP 182
             + +P+        VL+P G L     N    L  +    NF+  QA + +        
Sbjct: 124 WVLENPQRAYGEWLRVLKPHGKLINFDANWFLHLRDDTARRNFEEGQAAVVEHGFELKES 183

Query: 183 DYPRDPAQVYLWLEEAGW 200
           D+  +   ++  L  +G 
Sbjct: 184 DHGGELDNIFRELPLSGC 201


>UniRef50_C8VZ57 Methyltransferase type 11 n=1 Tax=Desulfotomaculum acetoxidans DSM
           771 RepID=C8VZ57_DESAS
          Length = 240

 Score =  139 bits (350), Expect = 1e-31,   Method: Composition-based stats.
 Identities = 49/205 (23%), Positives = 79/205 (38%), Gaps = 14/205 (6%)

Query: 2   QDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIK 61
            +  FDDIA K+         G+L   +  +   +   ++      VLD G G G   I 
Sbjct: 6   SNPTFDDIAAKYD-LWAKLPLGKLCAKLENEAFFKAYGDIAGSDP-VLDIGCGTGNYIIN 63

Query: 62  MAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAV 121
           +A  G  V   D S  M+  A+Q    +G   ++  +H  A+++    E     ++    
Sbjct: 64  LAGCGLDVTGLDASENMLAVARQKLTKQGFQASL--VHSLAENIP-FKEHSFKTVICSLA 120

Query: 122 LEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTLS 181
           LE++  P  V+Q ++ VL+P G   L F N       NM      YVQ  +        +
Sbjct: 121 LEFMGRPEKVVQEIFRVLQPSGQFILAFLN--FWSPWNMYRMLKGYVQPTIY-------N 171

Query: 182 PDYPRDPAQVYLWLEEAGWQIMGKT 206
                    V   L+EAG+      
Sbjct: 172 NANFMSRYYVNKVLKEAGFTDFSYY 196


>UniRef50_Q89BX8 Bll8020 protein n=1 Tax=Bradyrhizobium japonicum RepID=Q89BX8_BRAJA
          Length = 299

 Score =  139 bits (350), Expect = 1e-31,   Method: Composition-based stats.
 Identities = 53/240 (22%), Positives = 92/240 (38%), Gaps = 28/240 (11%)

Query: 14  SRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLR-VLDAGGGEGQTAIKMAERGH--QVI 70
             +     +  L  AI     D +L  + P K   VLD   G G  A ++AERGH  +++
Sbjct: 37  DASAPELYERYLVPAITSVWADDLLDRIDPAKGECVLDVACGTGVVARRLAERGHVGRLV 96

Query: 71  LCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRS 130
             DL+  M+  A+        S ++++   +A D+        D++L    L++  D   
Sbjct: 97  GIDLNGAMLAVARAK------SSDVEWTEGSALDLP-FATRSFDVVLCQLGLQFFPDRPQ 149

Query: 131 VLQTLWSVLRPGGVLSLMFYN-----AHGLLMHNMVAGNFDYVQAGMPKKKKRTLSPDYP 185
            L+ +  VL+P G L L  Y+              + G      +   + +  T +    
Sbjct: 150 ALREMARVLKPSGRLGLSVYSAIEHTPAANAFVQALDGFLGPESSRTKRAEHLTCN---- 205

Query: 186 RDPAQVYLWLEEAGWQIMGKT------GVRVFHDYLREKHQQRDCYEALLELETRYCRQE 239
               +V  W+ +AG+  +G        G     DY+R +        ALL  E    R+ 
Sbjct: 206 --ADEVGNWVRQAGFDRVGVETVTKQIGFPSALDYVRFQLTAT-PMAALLTREDDAGRER 262


>UniRef50_A6ULP8 Methyltransferase type 11 n=2 Tax=Proteobacteria RepID=A6ULP8_SINMW
          Length = 264

 Score =  139 bits (350), Expect = 1e-31,   Method: Composition-based stats.
 Identities = 55/284 (19%), Positives = 97/284 (34%), Gaps = 50/284 (17%)

Query: 1   MQDRNFDDIAEKFSRNIYGTTKGQ------LRQAILWQDLDRVLAEMGPQKLRVLDAGGG 54
           M D+  +++A ++++N    T          R    +    + L  +    L VLD G G
Sbjct: 1   MTDQAQEEVAARWNQNADQWTNDVRNGYDVYRDLFTFPAFQQCLPPI--AGLEVLDFGCG 58

Query: 55  EGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVD 114
           EG      A  G +V   D+S  +I+ A+QA  A  V   + +   +         +  D
Sbjct: 59  EGSNTRHFARMGAKVTGIDISQGLIEHARQAEVADPVG--VTYKVASYSSDTGFPASSFD 116

Query: 115 LILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNA-------------HGLLMHNMV 161
            +L    L    D +  +   + +LRPGG ++    +              HG      V
Sbjct: 117 AVLSTMALMDGPDFQGAMCEAYRLLRPGGFVAFSVLHPCFITPGLQWQKDEHGRTTGLCV 176

Query: 162 AGNFDYVQAGMPKKKKRTLS---------PDYPRDPAQVYLWLEEAGWQIMGKTGVRVFH 212
           A  FD        K     +         P +PR        +  AG++I          
Sbjct: 177 ARYFDRSSFTEHWKFGNRPTGENVVPFAVPRFPRTIGDYLNAVASAGFRISRI------- 229

Query: 213 DYLREKHQQRDCYEALLELETRYCRQEPYITLGRYIHV-TARKP 255
                  ++    E   +   R+ R   +  LG ++ +  A +P
Sbjct: 230 -------EEPQPTEEACKTVPRFSR---WRDLGAFLLLVVAERP 263


  Database: uniref50.fasta
    Posted date:  Mar 8, 2010 10:38 AM
  Number of letters in database: 1,040,396,356
  Number of sequences in database:  3,077,464
  
Lambda     K      H
   0.310    0.157    0.464 

Lambda     K      H
   0.267   0.0484    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,674,303,318
Number of Sequences: 3077464
Number of extensions: 74157828
Number of successful extensions: 388070
Number of sequences better than 1.0e-01: 250
Number of HSP's better than  0.1 without gapping: 13822
Number of HSP's successfully gapped in prelim test: 18167
Number of HSP's that attempted gapping in prelim test: 333341
Number of HSP's gapped (non-prelim): 35547
length of query: 261
length of database: 1,040,396,356
effective HSP length: 126
effective length of query: 135
effective length of database: 652,635,892
effective search space: 88105845420
effective search space used: 88105845420
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.0 bits)
S2: 92 (39.8 bits)
