BLASTP 2.2.22 [Sep-27-2009]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= batch____
         (523 letters)

Database: uniref50.fasta 
           3,077,464 sequences; 1,040,396,356 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P39829 D-galactarate dehydratase n=231 Tax=cellular org...  1074   0.0  
UniRef50_A5FZN2 Galactarate dehydratase n=111 Tax=Bacteria RepID...   318   2e-85
UniRef50_D1BWK3 Galactarate dehydratase n=1 Tax=Xylanimonas cell...   314   5e-84
UniRef50_Q21ZN4 Galactarate dehydratase n=8 Tax=Proteobacteria R...   306   1e-81
UniRef50_D0D8F8 D-galactarate dehydratase n=2 Tax=Rhodobacterace...   304   5e-81
UniRef50_A6W5I2 Altronate dehydratase n=32 Tax=Bacteria RepID=A6...   300   6e-80
UniRef50_D2QZ01 Altronate dehydratase n=1 Tax=Pirellula staleyi ...   295   3e-78
UniRef50_C1ZG32 Altronate dehydratase n=1 Tax=Planctomyces limno...   288   3e-76
UniRef50_C8T5I2 D-galactarate dehydratase n=3 Tax=Enterobacteria...   284   6e-75
UniRef50_Q028V7 Altronate dehydratase n=1 Tax=Candidatus Solibac...   282   2e-74
UniRef50_A6VSK2 Altronate dehydratase n=7 Tax=Proteobacteria Rep...   269   2e-70
UniRef50_A9KNI4 Altronate dehydratase n=3 Tax=Clostridiales RepI...   260   1e-67
UniRef50_C5SJY8 Altronate dehydratase n=3 Tax=Proteobacteria Rep...   255   3e-66
UniRef50_A0RPU2 Altronate hydrolase n=10 Tax=Bacteria RepID=A0RP...   254   6e-66
UniRef50_Q7UKI4 Altronate hydrolase n=2 Tax=Planctomycetales Rep...   250   1e-64
UniRef50_O34673 Altronate hydrolase n=80 Tax=Bacteria RepID=UXAA...   244   7e-63
UniRef50_C9B1P2 Altronate dehydratase n=9 Tax=Bacteria RepID=C9B...   241   5e-62
UniRef50_Q5WIY9 Altronate hydrolase C-terminus n=5 Tax=Firmicute...   235   4e-60
UniRef50_C6J327 Altronate dehydratase n=1 Tax=Paenibacillus sp. ...   232   3e-59
UniRef50_A7Z3M9 UxaA n=20 Tax=Bacteria RepID=A7Z3M9_BACA2             231   6e-59
UniRef50_B0T3J7 Altronate dehydratase n=15 Tax=Bacteria RepID=B0...   220   9e-56
UniRef50_B0K1I9 Altronate dehydratase n=10 Tax=Firmicutes RepID=...   215   3e-54
UniRef50_P42604 Altronate hydrolase n=77 Tax=Bacteria RepID=UXAA...   214   6e-54
UniRef50_C7PV23 Altronate dehydratase n=13 Tax=Bacteria RepID=C7...   210   8e-53
UniRef50_A0M231 Altronate hydrolase n=9 Tax=Bacteria RepID=A0M23...   210   9e-53
UniRef50_B5FMP6 Hydrolase, UxaA family n=75 Tax=cellular organis...   210   1e-52
UniRef50_C4X086 Altronate hydrolase n=14 Tax=Bacteria RepID=C4X0...   209   2e-52
UniRef50_Q6L323 Altronate hydrolase n=1 Tax=Picrophilus torridus...   198   5e-49
UniRef50_C9KKM7 Hydrolase, UxaA family n=1 Tax=Mitsuokella multa...   197   6e-49
UniRef50_D0ZBA7 Altronate hydrolase n=15 Tax=Bacteria RepID=D0ZB...   197   1e-48
UniRef50_D1Y174 D-galactarate dehydratase (GalcD) n=3 Tax=Bacter...   192   2e-47
UniRef50_D2QEC5 Altronate dehydratase n=2 Tax=Sphingobacteriales...   191   5e-47
UniRef50_D1Y193 Galactarate dehydratase n=1 Tax=Pyramidobacter p...   190   1e-46
UniRef50_D2S1M0 Altronate dehydratase n=1 Tax=Haloterrigena turk...   186   2e-45
UniRef50_C1NB77 Altronate dehydratase n=2 Tax=Enterobacteriaceae...   185   3e-45
UniRef50_C0CW83 Putative uncharacterized protein n=1 Tax=Clostri...   183   1e-44
UniRef50_B8FML6 Altronate dehydratase n=1 Tax=Desulfatibacillum ...   182   3e-44
UniRef50_UPI0001C34772 Altronate dehydratase n=1 Tax=Providencia...   182   4e-44
UniRef50_C4STJ6 Altronate dehydratase n=1 Tax=Yersinia frederiks...   171   6e-41
UniRef50_UPI00017F3110 galactarate dehydratase n=1 Tax=Escherich...   158   4e-37
UniRef50_Q0KC73 D-Galactarate dehydratase n=4 Tax=Burkholderiale...   154   8e-36
UniRef50_C5EFV8 Hydrolase n=1 Tax=Clostridiales bacterium 1_7_47...   151   6e-35
UniRef50_Q13SA4 Altronate dehydratase n=48 Tax=Bacteria RepID=Q1...   143   2e-32
UniRef50_B5IW17 D-galactarate dehydratase / Altronate hydrolase,...   142   3e-32
UniRef50_A8RT57 Putative uncharacterized protein n=1 Tax=Clostri...   138   5e-31
UniRef50_B1M8U1 Altronate dehydratase n=55 Tax=root RepID=B1M8U1...   136   2e-30
UniRef50_A9V9F3 Predicted protein n=1 Tax=Monosiga brevicollis R...   136   2e-30
UniRef50_Q1AYL8 D-galactarate dehydratase/Altronate hydrolase-li...   135   4e-30
UniRef50_C5EF38 Altronate dehydratase n=2 Tax=Clostridiales RepI...   127   1e-27
UniRef50_D0Z3R7 Altronate hydrolase n=2 Tax=Bacteria RepID=D0Z3R...   124   1e-26
UniRef50_C2DK38 Putative uncharacterized protein n=2 Tax=Escheri...   123   2e-26
UniRef50_A8H9C8 D-galactarate dehydratase/Altronate hydrolase do...   121   5e-26
UniRef50_B6WWW3 Putative uncharacterized protein n=2 Tax=Desulfo...   115   4e-24
UniRef50_D2PZR0 D-galactarate dehydratase/Altronate hydrolase do...   112   2e-23
UniRef50_A7VSH2 Putative uncharacterized protein n=1 Tax=Clostri...   112   4e-23
UniRef50_B5JYR2 D-Galactarate dehydratase n=1 Tax=Octadecabacter...   111   5e-23
UniRef50_B9MJB7 SMP-30/Gluconolaconase/LRE domain protein n=1 Ta...    73   2e-11
UniRef50_B7DPM4 Altronate dehydratase n=1 Tax=Alicyclobacillus a...    57   1e-06
UniRef50_C5EF39 Altronate hydrolase n=3 Tax=Clostridiales RepID=...    56   3e-06
UniRef50_D2S1L8 Altronate dehydratase-like protein n=1 Tax=Halot...    55   8e-06
UniRef50_Q0RXU4 Possible sulfolactate sulfo-lyase small subunit ...    51   1e-04
UniRef50_C5EFR7 Predicted protein n=1 Tax=Clostridiales bacteriu...    50   3e-04
UniRef50_D2RM01 SAF domain protein n=3 Tax=Bacteria RepID=D2RM01...    49   4e-04
UniRef50_UPI00017F2C45 Altronate dehydratase n=2 Tax=Enterobacte...    48   8e-04
UniRef50_D1Y192 Mannonate dehydratase n=1 Tax=Pyramidobacter pis...    48   0.001
UniRef50_C1XHK9 Altronate dehydratase n=2 Tax=Meiothermus RepID=...    47   0.001
UniRef50_A7VSH3 Putative uncharacterized protein n=1 Tax=Clostri...    47   0.002
UniRef50_B5J029 Putative uncharacterized protein n=1 Tax=Octadec...    47   0.002
UniRef50_A8MAM1 SAF domain protein n=5 Tax=cellular organisms Re...    47   0.002
UniRef50_B4TB53 Hydrolase, UxaA family n=14 Tax=Bacteria RepID=B...    46   0.003
UniRef50_C0CW84 Putative uncharacterized protein n=1 Tax=Clostri...    45   0.005
UniRef50_B8FML5 SAF domain protein n=1 Tax=Desulfatibacillum alk...    45   0.005
UniRef50_C0GPG6 SAF domain protein n=1 Tax=Desulfonatronospira t...    45   0.009
UniRef50_A1HS78 Hydrolase, UxaA family n=2 Tax=Thermosinus carbo...    44   0.011
UniRef50_B5JYR1 Altronate hydrolase n=1 Tax=Octadecabacter antar...    44   0.016
UniRef50_B1B868 Altronate hydrolase n=7 Tax=cellular organisms R...    43   0.024
UniRef50_Q9HIE8 Putative uncharacterized protein Ta1392 n=1 Tax=...    43   0.025
UniRef50_C0CYJ4 Putative uncharacterized protein n=1 Tax=Clostri...    43   0.034
UniRef50_D1U489 SAF domain protein n=1 Tax=Desulfovibrio aespoee...    43   0.035
UniRef50_C8ZXV8 D-galactarate dehydratase n=1 Tax=Enterococcus g...    42   0.060
UniRef50_Q6L322 Altronate hydrolase n=1 Tax=Picrophilus torridus...    42   0.066
UniRef50_B8G2E2 SAF domain protein n=2 Tax=Desulfitobacterium ha...    42   0.085

>UniRef50_P39829 D-galactarate dehydratase n=231 Tax=cellular organisms
           RepID=GARD_ECOLI
          Length = 523

 Score = 1074 bits (2778), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 523/523 (100%), Positives = 523/523 (100%)

Query: 1   MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDI 60
           MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDI
Sbjct: 1   MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDI 60

Query: 61  PANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTF 120
           PANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTF
Sbjct: 61  PANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTF 120

Query: 121 EGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCG 180
           EGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCG
Sbjct: 121 EGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCG 180

Query: 181 VAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASI 240
           VAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASI
Sbjct: 181 VAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASI 240

Query: 241 VSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTAN 300
           VSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTAN
Sbjct: 241 VSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTAN 300

Query: 301 PAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGK 360
           PAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGK
Sbjct: 301 PAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGK 360

Query: 361 TDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDF 420
           TDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDF
Sbjct: 361 TDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDF 420

Query: 421 VCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEE 480
           VCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEE
Sbjct: 421 VCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEE 480

Query: 481 TIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAPVT 523
           TIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAPVT
Sbjct: 481 TIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAPVT 523


>UniRef50_A5FZN2 Galactarate dehydratase n=111 Tax=Bacteria RepID=A5FZN2_ACICJ
          Length = 538

 Score =  318 bits (816), Expect = 2e-85,   Method: Compositional matrix adjust.
 Identities = 194/495 (39%), Positives = 283/495 (57%), Gaps = 14/495 (2%)

Query: 16  IKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRYGEVIGY 75
           ++++D DNV + +    + +GT   +GL     IP+GHK+A   I A   + ++G++IG+
Sbjct: 42  VRLNDADNVLVAIEP--IASGTGVAEGLVTSARIPRGHKIASAPIEAGAPVRKFGQIIGF 99

Query: 76  AVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVGTKNL 135
           A  AI  G+W+ E  V + E    +TL     V     P    TF G+R A+G VGT+N 
Sbjct: 100 AKEAIAPGAWVHEHNVEVHEFARDYTLGEVKPVEPAAAPA---TFMGFRRANGQVGTRNY 156

Query: 136 LGITTSVHCVAGVVDYVVKIIERD-LLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRT 194
           + I +SV+C A V   +    ER  LL  +PNVDG+V L H  GCG+A +     +  RT
Sbjct: 157 IAILSSVNCAATVARQIALRAERSGLLDGFPNVDGIVPLTHGTGCGMAADGEGYELLERT 216

Query: 195 IHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSM 254
           +   + NPN  G V+ IGLGCE LQ  R+ T    ++  P      +++QD    G  + 
Sbjct: 217 LWGAACNPNVAG-VLFIGLGCEVLQIARM-TARYGLKDDP--RFHWMTIQDSG--GTPAT 270

Query: 255 VEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCG 314
           +E  L      L + +  +RE  PAS L++ +QCGGSDA+SG+TANPA+G A+D+LVR G
Sbjct: 271 IEAGLAALREILPRADAARREPLPASHLILALQCGGSDAYSGLTANPALGEAADILVRHG 330

Query: 315 ATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKG 374
            T + SE  E+  A HLL  RA +  V   LL  ++W+ +YL       + NPSPGNK G
Sbjct: 331 GTAILSETPEIYGAEHLLVHRAASRRVADDLLARIDWWRDYLARTGGQMNNNPSPGNKAG 390

Query: 375 GLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQ 434
           GL  ++EK+LG++AK G + +  V    +  T+RG ++  TP  D V  T QVA G  + 
Sbjct: 391 GLTTILEKSLGAVAKGGTTPLTAVYRYAEPVTERGFVFMDTPGYDPVSVTGQVAGGANIL 450

Query: 435 VFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFIL 494
            FTTGRG+ +G   VP IK+AT ++L  R    MDI+ G I +G  TI + G ++F  +L
Sbjct: 451 CFTTGRGSAFGCKPVPSIKLATNSDLYRRMETDMDIDCGDILSG-TTIAQKGEEIFRHLL 509

Query: 495 DVASGKKKTFSDQWG 509
           DVASG  +T S++ G
Sbjct: 510 DVASG-ARTKSERLG 523


>UniRef50_D1BWK3 Galactarate dehydratase n=1 Tax=Xylanimonas cellulosilytica DSM
           15894 RepID=D1BWK3_XYLCX
          Length = 533

 Score =  314 bits (805), Expect = 5e-84,   Method: Compositional matrix adjust.
 Identities = 195/515 (37%), Positives = 275/515 (53%), Gaps = 26/515 (5%)

Query: 14  FYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEH---IPQGHKVALLDIPANGEIIRYG 70
             + +H  D+VA+   D  L AG     G   I     +P+GHKVA+ D+P    + +YG
Sbjct: 1   MLLLLHPDDDVAVATRD--LAAGETLDAGARTITTTGPVPRGHKVAVADLPPGAPVHKYG 58

Query: 71  EVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSV 130
           +VIG A   +  G  +    +        H L   T     +P     TF+GYR ADG V
Sbjct: 59  QVIGVATAPLAAGEHVHAHNLGFEAGHRDHQLG-GTHTELAVPAGPRPTFQGYRRADGRV 117

Query: 131 GTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVV 190
           GT+N + I TSV+C A     +        L  YPNVDGV+ L H  GCG+  ++    +
Sbjct: 118 GTRNYVAILTSVNCSATTARMIAAQFGPQALAGYPNVDGVIALTHQSGCGLVPSSEGGQI 177

Query: 191 PIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLT-------------GTDDVQAIPV-- 235
            +RT+   + +PN  G V+V+GLGCE +  E+L T             GT    A PV  
Sbjct: 178 LLRTLRGYAAHPNIAG-VLVLGLGCEMVLTEQLTTRSGTGAFLGMPGVGTPPPPADPVLA 236

Query: 236 ---ESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSD 292
                  + SL  ++  G ++ V   +   ER L  ++ R+RE C  ++LV+ + CGGSD
Sbjct: 237 DIPADTVVESLTIQESGGVRAAVTAGVAAVERMLAVVDTRRREICDVADLVLALNCGGSD 296

Query: 293 AFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWY 352
            +SG+TANPA+G+ASD LV  GAT   +E  EV  A HLLT RAV  +V +RLL+ ++W+
Sbjct: 297 GYSGLTANPALGWASDRLVAYGATSALAETPEVFGAEHLLTRRAVTPQVAQRLLDRIDWW 356

Query: 353 DNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKR-GLI 411
            +Y   G      NPSPGNK GGL  ++EK+LG++AK G++ +  V    +R   R G +
Sbjct: 357 QDYTRAGGGSMDNNPSPGNKAGGLTTILEKSLGAVAKGGQADLAAVYEYAERMAPRGGFV 416

Query: 412 YAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDIN 471
           +  TP  D V  T  VA G  V VFTTGRG+ +G    P IK+AT T +     D MD++
Sbjct: 417 FMDTPGYDPVSVTGLVAGGSNVVVFTTGRGSVFGCRPTPSIKVATNTPMYRAMSDDMDVD 476

Query: 472 AGTIATGEETIEEVGWKLFHFILDVASGKKKTFSD 506
           AG I  GE T+E+VG ++   IL VASG+     D
Sbjct: 477 AGRIVEGEATVEQVGQEILDLILRVASGEPTVSED 511


>UniRef50_Q21ZN4 Galactarate dehydratase n=8 Tax=Proteobacteria RepID=Q21ZN4_RHOFD
          Length = 509

 Score =  306 bits (783), Expect = 1e-81,   Method: Compositional matrix adjust.
 Identities = 185/492 (37%), Positives = 263/492 (53%), Gaps = 15/492 (3%)

Query: 16  IKVHDTDNVAIIVNDNGLKAGTRFP-DGLELIEHIPQGHKVALLDIPANGEIIRYGEVIG 74
           I++H  D+V I  N   L +GT    + + +   IP GHK+A  +I     + RYG++IG
Sbjct: 7   IRLHINDDVVIARNQ--LISGTLIAQESVTVQGLIPAGHKMATRNIAEGEAVRRYGQIIG 64

Query: 75  YAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVGTKN 134
           +A R I  G  +    + + +           +  + +P  E   F+G    DG V T+N
Sbjct: 65  FASRPIMAGQHVHVHNLSIGDFN--RDYAYGKESVDTVPATEAAFFQGIVRGDGRVATRN 122

Query: 135 LLGITTSVHCVAGVVDYVVKIIERDLLPK----YPNVDGVVGLNHLYGCGVAINAPAAVV 190
            +GI TSV+C A V   +     RD+ P+    YPNVDGVV L H  GC +        V
Sbjct: 123 YIGILTSVNCSATVARAIADHFRRDIHPEALAAYPNVDGVVALTHGVGCAIDPQGEGLAV 182

Query: 191 PIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVG 250
             RT+   + + NF   V++IGLGCE  Q   LL      + + + + +I   QD    G
Sbjct: 183 LQRTLGGYACHANFA-SVLIIGLGCETNQISDLLATQGLKENVRLHTFTI---QDTG--G 236

Query: 251 FQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLL 310
               ++  +   +  L   N  QR+T  AS LVVG+QCGGSD +SG++ANP +G A DLL
Sbjct: 237 TVKTIQHGIDRIQEMLPAANAVQRQTVSASHLVVGLQCGGSDGYSGISANPVLGAAVDLL 296

Query: 311 VRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPG 370
           VR G T + SE  E+  A HLLT RAV   VG++L++ + W++++          NPS G
Sbjct: 297 VRQGGTAILSETPEIYGAEHLLTRRAVTPAVGEKLVQRIRWWEDHCKRNGASMDNNPSSG 356

Query: 371 NKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASG 430
           NK GGL  V+EK+LG IAK G + +VEV    Q    +GL++  TP  D +  T QVA G
Sbjct: 357 NKAGGLTTVLEKSLGGIAKGGSTNLVEVYEYAQPVRAQGLVFMDTPGYDPISATGQVAGG 416

Query: 431 ITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLF 490
             +  FTTGRG+ YG    P +K+AT T L  R  D MDIN G +  G  TI E+G + F
Sbjct: 417 ANLICFTTGRGSAYGCAPTPSLKLATNTALWQRQADDMDINCGDVLDGSATIAELGQRFF 476

Query: 491 HFILDVASGKKK 502
             +L+ ASG++ 
Sbjct: 477 QMMLETASGRQS 488


>UniRef50_D0D8F8 D-galactarate dehydratase n=2 Tax=Rhodobacteraceae
           RepID=D0D8F8_9RHOB
          Length = 498

 Score =  304 bits (779), Expect = 5e-81,   Method: Compositional matrix adjust.
 Identities = 187/491 (38%), Positives = 280/491 (57%), Gaps = 21/491 (4%)

Query: 21  TDNVAIIVNDNGLKAG-TRFPDGLELIEHIPQGHKVALLDIPANGEIIRYGEVIGYAVRA 79
           TD VA++++D  + AG TR  DG+  +E IP+GHKVA   + A   +++YG+V+  A   
Sbjct: 12  TDTVAVVLSD--MDAGETR--DGITALEAIPRGHKVARKAMKAGDPVLKYGQVMAVASVD 67

Query: 80  IPRGSWIDESMVVLPEAPPLHTLPLA-TKVPEPLPPLEGYTFEGYRNADGSVGTKNLLGI 138
           IP G+ +      LPE    H +  A  ++PE   P    TF+G+   DG VGT+N +G+
Sbjct: 68  IPEGAHVHVQNCALPEGS--HGISAAQARLPEA--PTRN-TFQGFARPDGRVGTRNYIGV 122

Query: 139 TTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNI 198
             SV+C   V D +     R LLPKYPNVDG   + H  GCG+A         + T+   
Sbjct: 123 IASVNCSTTVCDAIAAEANRTLLPKYPNVDGFAPIVHDQGCGMANKGEGFDALVLTLKGY 182

Query: 199 SLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDI 258
             +PNFGG V++IGLGCE  Q   L   T+  +    E     ++Q+    G +S V+  
Sbjct: 183 RDHPNFGG-VLIIGLGCEVNQ-LTLYKPTEWTR----ERFKTFNIQEVG--GSRSAVKRA 234

Query: 259 LQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVM 318
           L + E      N+  R   P S+L +GMQCGGSD FSG+TANPA+G ASD+LV  G T +
Sbjct: 235 LDLLEPIAAMANEDTRSEQPVSKLTLGMQCGGSDGFSGITANPALGVASDMLVTAGGTSI 294

Query: 319 FSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGLAN 378
            SE  E+  A HLL  RA +E  G+++ + + W+ +Y +        NPSPGNKKGGL  
Sbjct: 295 LSETPEIYGAEHLLIARA-DEATGQKIEDMIVWWRDYASKNGASLDNNPSPGNKKGGLTT 353

Query: 379 VVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTT 438
           ++EK+LG++AK G + +    +  ++    G +Y  +P  D V  T QVASG  +  FTT
Sbjct: 354 ILEKSLGAVAKGGLAPLSGAFAYSEKIDTHGFVYMDSPGYDPVAATGQVASGANLIAFTT 413

Query: 439 GRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVAS 498
           GRG+ +G    P IK+++ ++LA    + +DI+ G +     ++ E+G +++  +LDVAS
Sbjct: 414 GRGSCFGAKPAPSIKLSSNSQLARSMAEDIDIDCGGVVEQGVSLTEMGERIYDLLLDVAS 473

Query: 499 GKKKTFSDQWG 509
           G +KT S+++G
Sbjct: 474 G-RKTMSEEFG 483


>UniRef50_A6W5I2 Altronate dehydratase n=32 Tax=Bacteria RepID=A6W5I2_KINRD
          Length = 533

 Score =  300 bits (769), Expect = 6e-80,   Method: Compositional matrix adjust.
 Identities = 189/482 (39%), Positives = 265/482 (54%), Gaps = 18/482 (3%)

Query: 43  LELIEHIPQGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWI---------DESMVVL 93
           L +   +P GHKVAL D+ A   + +YG++IG A   I  G  +          ++    
Sbjct: 48  LTVRTDVPAGHKVALRDVAAGEAVRKYGQLIGLASAPIAAGEHVHVHNLAFTASQAGAGS 107

Query: 94  PEAPPLHTLPLATKVPEPL-PPLEGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYV 152
            +A P          P PL PP E  TF+G   ADG V T+N +GI TSV+C A     +
Sbjct: 108 ADAGPGGYAVGVDARPTPLVPPAERRTFDGIVRADGRVATRNYIGILTSVNCSATAARRI 167

Query: 153 VKIIER-DLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVI 211
                    L  YPNVDGVV L H  GCG+      A +  RTI   + +PNF   ++VI
Sbjct: 168 ADTFRWPGALDAYPNVDGVVALTHGTGCGMDALGEGAQLLRRTISGYARHPNFAA-LLVI 226

Query: 212 GLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQ 271
           GLGCE  Q   L +G D    +PV + +I  +         + VE + ++    L  ++ 
Sbjct: 227 GLGCEVNQVAALTSGFDLPPEVPVVAMTIQEIGGTTRT-VAAGVERVREL----LPVVDA 281

Query: 272 RQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHL 331
            +R   PASELV+G+ CGGSDA+SGVTANPA+G ASDLLV  G T + +E  EV  A HL
Sbjct: 282 VRRVPVPASELVLGLNCGGSDAWSGVTANPALGVASDLLVAQGGTSVLAETPEVYGAEHL 341

Query: 332 LTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSG 391
           LT RA + EV  +L+  + W++ Y          NPSPGNK GGL  ++EK+LG++AK G
Sbjct: 342 LTRRARDPEVAAKLVRRIRWWEEYTAAHGGSMDNNPSPGNKAGGLTTILEKSLGAVAKGG 401

Query: 392 KSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPV 451
            +A+  V    +  T +G  +  TP  D V  T  VA G  V  FTTGRG+ +G    P 
Sbjct: 402 SAALEAVYEYAEPITAKGFTFMDTPGYDPVSVTGLVAGGANVVCFTTGRGSVFGCKPAPS 461

Query: 452 IKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLH 511
           IK+AT +E+  R  + MD++ G + TGE+T+EE G +LF  IL+VASG++   S++ G+ 
Sbjct: 462 IKLATNSEVYARMDEDMDVDCGRVLTGEQTVEEAGRELFELILEVASGRRSK-SEELGVG 520

Query: 512 NQ 513
           ++
Sbjct: 521 DE 522


>UniRef50_D2QZ01 Altronate dehydratase n=1 Tax=Pirellula staleyi DSM 6068
           RepID=D2QZ01_9PLAN
          Length = 516

 Score =  295 bits (755), Expect = 3e-78,   Method: Compositional matrix adjust.
 Identities = 190/509 (37%), Positives = 280/509 (55%), Gaps = 26/509 (5%)

Query: 16  IKVHDTDNVAIIVN--DNGLK---AGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRYG 70
           I +H +DN+ +     D GLK   A T     + L   I  GHK+A+  I     + +YG
Sbjct: 12  IYLHPSDNICVAARTLDAGLKLDIAATT----ITLSSLIKIGHKIAIAPIAKGSFVYKYG 67

Query: 71  EVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSV 130
           ++IG A   I  G  +      L     +     +  +P  LPP+   TF GYR ADG  
Sbjct: 68  QIIGTATCDIAPGDHVHSHN--LTNGDFVRDYAKSQAIPAALPPITDRTFLGYRRADGKA 125

Query: 131 GTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVV 190
           GT+N + + ++V+C A V  Y+    ++ +L  YP++DGV+ L H  GCG+        +
Sbjct: 126 GTRNYIAVISTVNCSASVSKYIANRFDQSILKDYPSIDGVIALKHGGGCGLQYGGLQHQI 185

Query: 191 PIRTIHNISLNPNFGGEVMVIGLGCEK------LQPERLLTGTDDVQAIPVESASIVSLQ 244
             RT+  ++ +PN GG  ++IGLGCE       L  ++L+    + + +P     ++S+Q
Sbjct: 186 LARTLGGMAKHPNIGG-FLLIGLGCENAPMGYLLDSQKLIQIDGNKRNMP----PVLSMQ 240

Query: 245 DEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVG 304
           D    G    VE  +++    L K    +R   PASE+++G  CGGSD  SGVT NPA+G
Sbjct: 241 DLG--GTAKTVEAGIRMLGELLPKAADVKRVPIPASEIILGTNCGGSDGNSGVTCNPALG 298

Query: 305 YASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRS 364
            ASDLLVRCG T   +E TE+  A HLLT RA   EV  +LLE ++W+  +  M   +  
Sbjct: 299 VASDLLVRCGGTTALAETTEIYGAEHLLTRRARTPEVADKLLERIDWWLWHTKMYGVEID 358

Query: 365 ANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGT 424
            NPS GNK+GGL  + EK+LG++AK+G +A+ EV    +  T +G +   TP  D    T
Sbjct: 359 NNPSVGNKEGGLTTIAEKSLGAVAKTGTTALEEVYHYAEPMTAKGFVVMDTPGFDPPSVT 418

Query: 425 QQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEE 484
             VA G  V VFTTGRG+ +G   VP IK+A+ T +  R  D MDIN+G +  G +++E 
Sbjct: 419 GLVAGGANVVVFTTGRGSCFGCKPVPSIKVASNTPMYERMIDDMDINSGEVLHG-QSLEA 477

Query: 485 VGWKLFHFILDVASGKKKTFSDQWGLHNQ 513
            G ++F  IL VASG +KT S+Q G+ ++
Sbjct: 478 AGQEIFEKILSVASG-EKTKSEQHGIGDE 505


>UniRef50_C1ZG32 Altronate dehydratase n=1 Tax=Planctomyces limnophilus DSM 3776
           RepID=C1ZG32_PLALI
          Length = 526

 Score =  288 bits (738), Expect = 3e-76,   Method: Compositional matrix adjust.
 Identities = 191/522 (36%), Positives = 282/522 (54%), Gaps = 20/522 (3%)

Query: 16  IKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIP--QGHKVALLDIPANGEIIRYGEVI 73
           +++   D+VA+   +  L AG+   +G EL+   P   GHKVALL I A   I++YG+  
Sbjct: 9   LQLSPVDHVAVATQN--LPAGSVTHEGQELLIRQPVRAGHKVALLPIAAGTPILKYGQPF 66

Query: 74  GYAVRAIPRGSWIDESMVVL--PE-----APPLHTLPLATKVPEPLPPLEG-YTFEGYRN 125
             A R I  G  +    V +  PE     A P        +   P   +E   TF G R 
Sbjct: 67  AIASRDILAGEHVHTHNVRVMGPEDCQQLAKPNSASSSHDRSTSPTTHVENEMTFAGIRR 126

Query: 126 ADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINA 185
            DG V T+N + +  +V+C + VV  +V+ I +DLL +Y NVDGV+ L H  GC +    
Sbjct: 127 PDGRVATRNYVAVIGTVNCSSTVVRKIVRAISQDLLNQYENVDGVIPLVHSGGCAMEFGG 186

Query: 186 PAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPV----ESASIV 241
                  R +   + +PN G   +++GLGCE  Q   L+     VQ        +SA  +
Sbjct: 187 TDHRQLARILGGYARHPNIGA-YLLVGLGCETGQGSFLIEQEGLVQLRRSGEVQQSAPPL 245

Query: 242 SLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANP 301
            +  ++  G +  +E  L   +  L + N+ QRE+ PASELV+G++CGGSD FSG+TANP
Sbjct: 246 LVNIQEAGGVRRTIERALAALKELLPEANKCQRESIPASELVMGLKCGGSDGFSGLTANP 305

Query: 302 AVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKT 361
           A+G ASDLL+  G T + +E  E+    HLL  R+++ EV ++LL+++ W+  Y     T
Sbjct: 306 ALGVASDLLISQGGTALLAETPEIFGGEHLLASRSIDSEVSQKLLDKVAWWRAYAAKFGT 365

Query: 362 DRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFV 421
               NPS GNK+GGL  +VEK+LG+I K G S +V+VL   +R   RGL +  +P  D  
Sbjct: 366 TLDGNPSFGNKEGGLTTIVEKSLGAITKGGASPLVDVLDYAERVRHRGLNFMDSPGYDPA 425

Query: 422 CGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEET 481
             T  +ASG  V  FTTGRG+ +G    P +K++T T L  R  + MD +AG + +G  +
Sbjct: 426 SVTGLIASGAHVVCFTTGRGSCFGSKPAPTLKISTNTSLFERLSEEMDFDAGRVLSG-AS 484

Query: 482 IEEVGWKLFHFILDVASGKKKTFSDQWGL-HNQLAVFNPAPV 522
           I + G  L   +L VASG +KT S+Q G   ++   + P PV
Sbjct: 485 ISQTGQNLLRKVLKVASG-EKTCSEQQGFGDDEFFPWTPGPV 525


>UniRef50_C8T5I2 D-galactarate dehydratase n=3 Tax=Enterobacteriaceae
           RepID=C8T5I2_KLEPR
          Length = 172

 Score =  284 bits (726), Expect = 6e-75,   Method: Compositional matrix adjust.
 Identities = 138/156 (88%), Positives = 147/156 (94%)

Query: 1   MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDI 60
           MA+I IRQ++PTAFYIKV  TDNVAIIVND GL AGTRFPDGL L+EHIPQGHKVAL+DI
Sbjct: 1   MADIAIRQQSPTAFYIKVDPTDNVAIIVNDRGLTAGTRFPDGLTLVEHIPQGHKVALVDI 60

Query: 61  PANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTF 120
           PA+GEIIRYGEVIGYAVR IP+GSWIDES+V LP APPL+TLPLATKVPEPLPPLEGYTF
Sbjct: 61  PAHGEIIRYGEVIGYAVRDIPQGSWIDESLVELPTAPPLNTLPLATKVPEPLPPLEGYTF 120

Query: 121 EGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKII 156
           EGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKII
Sbjct: 121 EGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKII 156


>UniRef50_Q028V7 Altronate dehydratase n=1 Tax=Candidatus Solibacter usitatus
           Ellin6076 RepID=Q028V7_SOLUE
          Length = 511

 Score =  282 bits (722), Expect = 2e-74,   Method: Compositional matrix adjust.
 Identities = 191/511 (37%), Positives = 271/511 (53%), Gaps = 20/511 (3%)

Query: 16  IKVHDTDNVAIIVNDNGLKAGTRFP-DGLELI--EHIPQGHKVALLDIPANGEIIRYGEV 72
           I +H TDNVA  V    L AGT    DGL +   + IP GHK+AL DI     + RYG+V
Sbjct: 16  IHLHPTDNVA--VARVPLPAGTELRVDGLPVTVRDAIPAGHKIALWDIAPGETVERYGQV 73

Query: 73  IGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLA-TKVPEPLPPLEGYTFEGYRNADGSVG 131
           IG A   I  G  I    +   E    +  P   T VP P P  +  TF GY   DG VG
Sbjct: 74  IGRAKLPIDAGRHIHTHNLAYEELALDYEFPTTETAVPTPRP--DAPTFLGYPREDGRVG 131

Query: 132 TKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVP 191
           T+N + +  + +C A   + + +  E   LP  PNVDGVV   H  GCG A   P     
Sbjct: 132 TRNYIAVVAASNCAAHAAELIARSYEGVTLP--PNVDGVVAFPHGEGCGHAF-GPDVDQL 188

Query: 192 IRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGF 251
            RT+  + ++PN     +++GLGCE  Q +  L       A    +  +V +  +   G 
Sbjct: 189 RRTLGGVLVHPNVSA-ALILGLGCEVNQIDHYL------GAGSPRTNRLVGMTLQTSGGT 241

Query: 252 QSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLV 311
             ++    +   R  ++     R   PAS++++G+ CGGSD+FSG+TANPA+G+ SDLL 
Sbjct: 242 PGILAAARREIGRFFEQAAAENRVPVPASKIILGLNCGGSDSFSGITANPALGFCSDLLA 301

Query: 312 RCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGN 371
             GA  + +E  E+  A HLL  RA N E+  +LL  +  Y  YL+        NPSPGN
Sbjct: 302 ELGAASVLAETPEIFGAEHLLVRRARNREIADKLLGCISRYKKYLSRFDGSFDDNPSPGN 361

Query: 372 KKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGI 431
           K+GGL+N++EK+LG++AK G S +++V    ++ T  G  +  TP  D V  T   A G 
Sbjct: 362 KEGGLSNILEKSLGAVAKGGTSPLIDVYEYAEKITAPGFSFMNTPGYDPVSLTGLAAGGC 421

Query: 432 TVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFH 491
            +  FTTGRG+  G   +PVIK++T T       D MDINAG IA GE TI++ G ++FH
Sbjct: 422 NLIAFTTGRGSAIGFPTIPVIKISTNTHTYRAMPDNMDINAGAIADGESTIQQTGREIFH 481

Query: 492 FILDVASGKKKTFSDQWGLHNQLAVFNPAPV 522
            +L +ASG + T +++ G H +   +   PV
Sbjct: 482 ALLAIASG-RPTCAERLG-HKEFVPWRIGPV 510


>UniRef50_A6VSK2 Altronate dehydratase n=7 Tax=Proteobacteria RepID=A6VSK2_MARMS
          Length = 509

 Score =  269 bits (688), Expect = 2e-70,   Method: Compositional matrix adjust.
 Identities = 166/496 (33%), Positives = 264/496 (53%), Gaps = 10/496 (2%)

Query: 16  IKVHDTDNVAIIVNDNGLKAGTRFPD-GLELIEHIPQGHKVALLDIPANGEIIRYGEVIG 74
           IK+H  DNV I+     +  G + P+  L +   +  GHK+A   I A   II+Y   IG
Sbjct: 9   IKLHSNDNVCIV--RESVSIGQQVPEFNLRIRAQVSGGHKIAARLIEAGEPIIKYDTRIG 66

Query: 75  YAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVGTKN 134
            A+R I  G  +    + L +     +        + +      TF G   ++G V T+N
Sbjct: 67  VALRRIEAGDHVHTHNLELVDYERDPSFCQDVVPVDYVDVSARATFNGIVRSNGKVATRN 126

Query: 135 LLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRT 194
            +GI ++V+C + V+  +      + L  +PNVDG+V   H  GCG++  +    V  RT
Sbjct: 127 YIGILSTVNCSSTVIRQIADHFTPERLSAFPNVDGIVAFPHTSGCGMSSPSYHFDVLRRT 186

Query: 195 IHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSM 254
           +   + +PN  G V+++GLGCE+ +   L+      Q +  E++ + +L  +   G ++ 
Sbjct: 187 LSGYARHPNLAG-VLIVGLGCERNEMSSLIAS----QQLE-ENSHLQTLVMQAVGGTRAT 240

Query: 255 VEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCG 314
           +   +   E  L + N+  RE      L +G+QCGGSD FS +TANPA+G A D+LVR G
Sbjct: 241 IAAGIAAIESMLPEANKVVREPVSVEHLKIGLQCGGSDGFSAITANPALGMAMDILVRHG 300

Query: 315 ATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKG 374
            T + SE  E+    ++LT RA+++EVG++LL+ + W+D Y        +     GN+ G
Sbjct: 301 GTAILSETPEIHGVEYMLTRRAISQEVGQKLLDRLSWWDEYTRGHNGQFNGVVGQGNQAG 360

Query: 375 GLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQ 434
           GLAN+ EK+LGS  K G + +  V    +   + G ++  TP  D V  T Q+A G  + 
Sbjct: 361 GLANIFEKSLGSAMKGGTTPLQAVYEYAEPIEQNGFVFMDTPGYDPVSATGQIAGGANLI 420

Query: 435 VFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFIL 494
            FTTGRG+ +G    P IK+A+ + + NR  + MDIN G I  G+ ++EE+G  +F  I+
Sbjct: 421 CFTTGRGSMFGSKPAPTIKLASNSNMYNRLQEDMDINCGLILDGKMSLEEMGQHIFEHII 480

Query: 495 DVASGKKKTFSDQWGL 510
            VASG + T S++ GL
Sbjct: 481 KVASG-ESTSSERLGL 495


>UniRef50_A9KNI4 Altronate dehydratase n=3 Tax=Clostridiales RepID=A9KNI4_CLOPH
          Length = 493

 Score =  260 bits (664), Expect = 1e-67,   Method: Compositional matrix adjust.
 Identities = 176/512 (34%), Positives = 270/512 (52%), Gaps = 37/512 (7%)

Query: 15  YIKVHDTDNVAIIVNDNGLKAGTRFP-DGL--ELIEHIPQGHKVALLDIPANGEIIRYGE 71
           ++K++  DNVA+ +ND  L  G     DG+   L+E IP+GHK  L ++     +++YG 
Sbjct: 4   FVKINSKDNVAVALND--LTKGMTIEVDGVAVTLVEDIPRGHKFTLANLNEGENVLKYGF 61

Query: 72  VIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVG 131
            IG+  +A   GSW+  +  +      L T      V + L P E  TF GYR  +G VG
Sbjct: 62  PIGHLTKAAEMGSWV-HTQNIKTNLGELLTYSYEPNVNQ-LKPHEKATFMGYRRDNGKVG 119

Query: 132 TKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVP 191
            +N + I  +V CV  + + + K  +  L     +V+ ++   H YGC    +       
Sbjct: 120 IRNEVWIIPTVGCVNKIAEAMEKQFKEKLTG---SVEDIIAFPHPYGCSQMGDDQENT-- 174

Query: 192 IRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGF 251
            R I +  +N      V+V+GLGCE      L                 +   DE  + F
Sbjct: 175 -RIILSDLINHPNAAAVLVLGLGCENTNIAEL--------------KKYIGEYDEDRIKF 219

Query: 252 QSM--VEDILQIAERHLQKL----NQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGY 305
                VED +++AE  +++L     + +RE   A ELV+GM+CGGSD  SG+TANP VG 
Sbjct: 220 LQCQDVEDEMEVAEELIEQLISYAAKFEREPISADELVIGMKCGGSDGMSGITANPTVGV 279

Query: 306 ASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSA 365
            SDLL+  G T + +EV E+  A  LL  R  NEE+  + ++ +  + NY          
Sbjct: 280 FSDLLISQGGTTVLTEVPEMFGAETLLMARCENEELFDKTVDMINDFKNYFKSHNQTIYE 339

Query: 366 NPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQ 425
           NPSPGNKKGG++ + +K+LG   KSG + + +VL  G+    +GL   + P +D V  T 
Sbjct: 340 NPSPGNKKGGISTLEDKSLGCTQKSGSAPVKDVLKYGEIVKTKGLNLLSAPGNDLVASTA 399

Query: 426 QVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEV 485
             ASG  + +FTTGRGTP+    VP +K++T T LA +  + +D N GT+  G +T++ +
Sbjct: 400 LAASGAHMVLFTTGRGTPFA-SPVPTMKISTNTPLAMKKNNWIDFNCGTLVEG-KTLDIL 457

Query: 486 GWKLFHFILDVASGKKKTFSDQWGLHNQLAVF 517
           G +LF ++L VASG KK  S++ G H+ +A+F
Sbjct: 458 GEELFQYVLAVASG-KKVKSEEAGFHD-MAIF 487


>UniRef50_C5SJY8 Altronate dehydratase n=3 Tax=Proteobacteria RepID=C5SJY8_9CAUL
          Length = 515

 Score =  255 bits (651), Expect = 3e-66,   Method: Compositional matrix adjust.
 Identities = 174/495 (35%), Positives = 259/495 (52%), Gaps = 31/495 (6%)

Query: 15  YIKVHDTDNVAIIVNDNGLKAGTRFPDG---LELIEHIPQGHKVALLDIPANGEIIRYGE 71
           Y++VH TD+VAI V    L AG     G   L L   IP+GHK+AL DI     ++++G 
Sbjct: 24  YVRVHATDDVAIAVE--ALSAGEVLDFGDVQLTLGTDIPKGHKIALRDIAEGAPVLKFGF 81

Query: 72  VIGYAVRAIPRGSWIDESMVV--LPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGS 129
            IG+A+  I  G  +    +   L         P+A + P   P  +  TF GYR ADG 
Sbjct: 82  RIGHAIAPIKTGEHVHTHNLSTSLTGVEDYDYAPVAAEGPGSRP--DARTFMGYRRADGR 139

Query: 130 VGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGC---GVAINAP 186
           VG +N + I  +V CVA   + + K+       +   VDGV  L H  GC   G  +N  
Sbjct: 140 VGIRNEIWILCTVGCVARTSERLAKVASERFKGR---VDGVYALTHPLGCSQLGDDLNHT 196

Query: 187 AAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDE 246
             ++     H     PN GG V+++GLGCE  Q   L+   +      ++  +   ++DE
Sbjct: 197 RKLLAALAAH-----PNAGG-VLIVGLGCENNQLSALIGEIEGRTPDRLKYFAAQMVEDE 250

Query: 247 KHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYA 306
              G +++ E ++Q+ E+        QRE C  S+L +G++CGGSD FSG+TANP VG  
Sbjct: 251 HESGLEAL-EALVQVVEKD-------QRELCHVSDLAIGVKCGGSDGFSGLTANPLVGRV 302

Query: 307 SDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSAN 366
           +D++   G   + +E+ EV  A  +L  RA +E V  ++++ +  +  Y          N
Sbjct: 303 ADIVALAGGQSIMTEIPEVFGAERILMARAKDEGVFHQIVDVVNDFKQYFLDNNQPVFEN 362

Query: 367 PSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQ 426
           PSPGNK GG++ + EK+LG++ K G S + EVL  G+R T+ GL     P +D V  T  
Sbjct: 363 PSPGNKAGGISTLEEKSLGAVQKGGLSQLTEVLRYGERATQAGLSLLEAPGNDAVSSTAL 422

Query: 427 VASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVG 486
            A+G  + +FTTGRGTP G  A P +K+A+ T LA +    +D NAG    G +T++E  
Sbjct: 423 TAAGAVIVLFTTGRGTPLGFPA-PTLKIASNTALAEKKPHWIDFNAGQALEG-KTLDETA 480

Query: 487 WKLFHFILDVASGKK 501
             L   IL VASG++
Sbjct: 481 DDLMDLILRVASGER 495


>UniRef50_A0RPU2 Altronate hydrolase n=10 Tax=Bacteria RepID=A0RPU2_CAMFF
          Length = 505

 Score =  254 bits (649), Expect = 6e-66,   Method: Compositional matrix adjust.
 Identities = 158/467 (33%), Positives = 257/467 (55%), Gaps = 17/467 (3%)

Query: 42  GLELIEHIPQGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPE-----A 96
           G+ +IE I +GHK A  DI     II+Y  +IG A + I +G+WI    +         +
Sbjct: 27  GVTIIEDISKGHKFATKDIKKGEAIIKYSSIIGIANQDIKKGAWIHVHNIEGTRGRGDIS 86

Query: 97  PPLHTLPLATK-VPEPLPPLEGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKI 155
             LH      K   +     + Y  +GYR +DGS G +N + I  SVHC   VV+ +   
Sbjct: 87  GNLHIASQKLKNKKQAASNDKKYELQGYRRSDGSFGLRNHILILPSVHCANKVVEKIAAA 146

Query: 156 IERDLLPKYPNVDGVVGLNHLYGCG-VAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLG 214
           I   L         +V + H +GC  +  +A      + T+     NPN  G V+VIGLG
Sbjct: 147 INYGLGLGNDECK-IVYVTHQHGCSQLEFDARQT---MDTLVGNGANPNVYG-VLVIGLG 201

Query: 215 CEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQR 274
           CE +  + +     D    P +     ++Q     G +  +E  ++IA+  LQ   + ++
Sbjct: 202 CEVISAQNVAKEIKD--RAPYKEVEYFTIQQSG--GTRKSIEKGIKIAKNMLQNALKFKK 257

Query: 275 ETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTP 334
                S+L++G +CGGSD+FSG++ANPA+G ASD++++ G +V+ +E TE+  A H+L  
Sbjct: 258 SRGDLSDLILGTECGGSDSFSGLSANPALGVASDIVIQKGGSVILAETTELIGAEHILAA 317

Query: 335 RAVNEEVGKRLLEEMEWYDNYLNMGKTD-RSANPSPGNKKGGLANVVEKALGSIAKSGKS 393
           R++NE++ ++++  +  ++  +   K D R ANPSPGN +GGL+++ EK+LG I K+G  
Sbjct: 318 RSINEDIKEQVISTITSFEQRVLDSKADIRGANPSPGNIEGGLSSIEEKSLGCIYKAGNQ 377

Query: 394 AIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIK 453
            ++ V    Q  T++GL    TP +D    +  VA G  + VFTTGRGTP G    P IK
Sbjct: 378 PVISVKRYAQPITQKGLTLMDTPGNDIEQLSAMVAGGCNICVFTTGRGTPTGSPITPTIK 437

Query: 454 MATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGK 500
           +++ + + +   D +DINAG+I  G++ I+EVG ++  FI+ +++GK
Sbjct: 438 VSSNSAIYHNMNDAIDINAGSIIDGQKNIKEVGEEILDFIVAISNGK 484


>UniRef50_Q7UKI4 Altronate hydrolase n=2 Tax=Planctomycetales RepID=Q7UKI4_RHOBA
          Length = 634

 Score =  250 bits (638), Expect = 1e-64,   Method: Compositional matrix adjust.
 Identities = 178/516 (34%), Positives = 265/516 (51%), Gaps = 31/516 (6%)

Query: 16  IKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRYGEVIGY 75
           +++HD DNV +      L AG    +       +P GHKVA   IPA   +I++G+ IG 
Sbjct: 115 VRLHDGDNVWMAAW--ALVAGETIGNLRIAGSAVPAGHKVAAQAIPAGELVIKFGQPIGK 172

Query: 76  AVRAIPRGSWID-----ESMVVLPEAPPLHTLPLATKVP--EPLPPLEGYTFEGYRNADG 128
           A   I  G  +      ++  V  +   L     +   P  +P  P E  TFEG+   DG
Sbjct: 173 ASCDIGVGEHVHSHNLVDAHQVDSDWRSLVGTAFSKSAPAKKPAVPAE-KTFEGFVRPDG 231

Query: 129 SVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAA 188
            VGT+N + I   V+C A V  +V      + L ++PNVDG+    H  GC +       
Sbjct: 232 QVGTRNYVQILARVNCSATVCHHVAARFPPERLAEFPNVDGIAIGTHTTGCALRYAGQKQ 291

Query: 189 VVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERL-----LTGTDDVQAIPV-----ESA 238
            +  R +   + + N G   + IGLGCE+  PE L     L    D +++PV     ES 
Sbjct: 292 QMLGRVLKGYAGHANVG-SCLTIGLGCEQTTPEYLSEHHQLVAISDPRSLPVTSPESESV 350

Query: 239 SIVSLQDEKHVGFQSMVEDILQIAERHLQKL----NQRQRETCPASELVVGMQCGGSDAF 294
           S   L  +   G ++ ++     AE+HL+ +    NQ  R T PA  L + ++CGGSD  
Sbjct: 351 STTMLTMQAEGGTRATIDR----AEKHLETMLEIANQNSRTTVPAHHLRLALECGGSDGH 406

Query: 295 SGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDN 354
           SG TANP VG  +D +V  G   + SE TE+  A HLL  R+ +E V +RL+++++W+  
Sbjct: 407 SGWTANPLVGAIADRMVAFGGAAVLSETTELIGAEHLLVARSRDESVAQRLMDKVDWWKK 466

Query: 355 YLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAA 414
           ++ M   +   NPS GNK GGL  + EK+LG+++KSG   +  VL       K+GL    
Sbjct: 467 HVAMYGGEIDNNPSIGNKAGGLTTITEKSLGAVSKSGTGILDGVLDYADTVPKQGLYVMD 526

Query: 415 TPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGT 474
           +P  D    T +VA G  + +FTTGRG+ +G   VPVIK+A+ + L +   D MD NAG 
Sbjct: 527 SPGFDPSSVTGKVAGGCNLVLFTTGRGSCFGGKPVPVIKIASHSTLFHAMRDDMDWNAGQ 586

Query: 475 IATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGL 510
           +  G   +EE+  +LF  +L  ASG  +T S++ GL
Sbjct: 587 LLEG-VAMEELADQLFEELLRFASG-TQTASERLGL 620


>UniRef50_O34673 Altronate hydrolase n=80 Tax=Bacteria RepID=UXAA_BACSU
          Length = 497

 Score =  244 bits (622), Expect = 7e-63,   Method: Compositional matrix adjust.
 Identities = 167/492 (33%), Positives = 261/492 (53%), Gaps = 25/492 (5%)

Query: 15  YIKVHDTDNVAIIVNDNGLKAGTR---FPDGLELIEHIPQGHKVALLDIPANGEIIRYGE 71
           +IK+H  DNV + + D  ++ G R   +   +E+ + I +GHK+AL  I  N  I++YG 
Sbjct: 4   FIKIHKQDNVLLALRD--IQKGERLHAYGVSIEVKDDIKRGHKIALQSIKENDSIVKYGF 61

Query: 72  VIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVP---EPLPPLEGYTFEGYRNADG 128
            IG+A + I  G    E + V      L  + L +  P   E     E  TF+G+R  +G
Sbjct: 62  PIGHASQDISIG----EHIHVHNTKTNLSDIQLYSYTPRFDENPYSNENRTFKGFRRENG 117

Query: 129 SVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAA 188
             G +N L I  +V CV G+ + +++   R+     P  D V+ L H YGC    +    
Sbjct: 118 DAGVRNELWIVPTVGCVNGIAEKMLQRFVRETGDIAP-FDNVLVLKHQYGCSQLGDDHEN 176

Query: 189 VVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKH 248
              I  + N   +PN GG V+V+GLGCE  +  R+     DV    V+     S+ DE  
Sbjct: 177 TKQI--LLNAIRHPNAGG-VLVLGLGCENNELARMKEALQDVNLKRVKFLESQSVTDEME 233

Query: 249 VGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASD 308
            G  +++++I + A+         +RE  P SEL +G++CGGSD FSG+TANP +G  SD
Sbjct: 234 AGV-ALLKEIHEAAK-------GDKREDIPLSELKIGLKCGGSDGFSGITANPLLGRFSD 285

Query: 309 LLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPS 368
            L+  G + + +EV E+  A  +L  RA NEEV  ++++ +  +  Y          NPS
Sbjct: 286 YLIAQGGSTVLTEVPEMFGAETILMQRAANEEVFHKIVDLINDFKQYFIKHDQPVYENPS 345

Query: 369 PGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVA 428
           PGNK GG++ + +K+LG   K+G S + +VL  G+    +GL   + P +D +  +   A
Sbjct: 346 PGNKAGGISTLEDKSLGCTQKAGISPVTDVLKYGEVLKTKGLTLLSAPGNDLIASSALAA 405

Query: 429 SGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWK 488
           +G  + +FTTGRGTP+G   VP +K+AT TEL       +D NAG +A  +   E V  +
Sbjct: 406 AGCQIVLFTTGRGTPFGTF-VPTVKVATNTELYEAKPHWIDFNAGLLAEDDVHEEYVLRE 464

Query: 489 LFHFILDVASGK 500
             H++++VASG+
Sbjct: 465 FIHYMIEVASGQ 476


>UniRef50_C9B1P2 Altronate dehydratase n=9 Tax=Bacteria RepID=C9B1P2_ENTCA
          Length = 503

 Score =  241 bits (615), Expect = 5e-62,   Method: Compositional matrix adjust.
 Identities = 173/503 (34%), Positives = 250/503 (49%), Gaps = 38/503 (7%)

Query: 9   ETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFP-DGLELIEHIPQGHKVALLDIPANGEII 67
           ETP A  +K+H  DNVA+ +     K    F    + L E IPQGHK+AL D+  + ++I
Sbjct: 7   ETP-AQLLKLHPKDNVAVALKPLAAKTTLAFEGQTITLFEDIPQGHKIALKDLAQSQDVI 65

Query: 68  RYGEVIGYAVRAIPRGSWIDESMV--------VLPEAPPLHTLPLATKVPEPLPPLEGYT 119
           +YG  IG+ +  +  G W+    V            AP LH +           P    T
Sbjct: 66  KYGYPIGHLLTDVKTGQWLHTHNVKTNLSGTLAYTYAPDLHPVRY---------PKRAAT 116

Query: 120 FEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGC 179
           F+GYR A+G VG +N L I  +V C+ G+ + +V+  +++  P     D +  L H YGC
Sbjct: 117 FQGYRRANGKVGIRNDLLIVPTVGCINGIAEIIVENFKKNH-PDLGTFDHITILKHPYGC 175

Query: 180 GV--AINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVES 237
                 +     + I  +H+    PN GG V+V GLGCE            D     V+ 
Sbjct: 176 SQLGQDHQNTRQILIDAVHH----PNAGG-VLVFGLGCENNTVPEFKKNLGDYDPKRVKF 230

Query: 238 ASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGV 297
                  DE  VG   + E +    E         QRE  P SEL +G++CGGSD FSG+
Sbjct: 231 MVAQESDDEIAVGESLLEELLEAAKED--------QREAVPLSELKIGLKCGGSDGFSGI 282

Query: 298 TANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLN 357
           TANP +G  SD LV  G + + +EV E+  A  +L  RA +E   +++L  +  + +Y  
Sbjct: 283 TANPLLGAFSDFLVSQGGSTVLTEVPEMFGAEQVLMARAQDEATFEKILHLINDFKDYFL 342

Query: 358 MGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPA 417
                   NPSPGNK GG+  + +K+LG   KSG SA+V+VL  G++  K GL     P 
Sbjct: 343 AYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGTSAVVDVLKYGEKLRKPGLSLLEGPG 402

Query: 418 SDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIAT 477
           +D V  +   ++   + +FTTGRGTP+G   VP +K+AT  E+ ++    MD NAG +  
Sbjct: 403 NDLVAASALASADCQLVLFTTGRGTPFGAY-VPTMKVATNQEIYHKKPHWMDFNAGRLL- 460

Query: 478 GEETIEEVGWKLFHFILDVASGK 500
            EE +E V       I+D ASGK
Sbjct: 461 -EEPMEVVLEDFIQAIIDTASGK 482


>UniRef50_Q5WIY9 Altronate hydrolase C-terminus n=5 Tax=Firmicutes
           RepID=Q5WIY9_BACSK
          Length = 388

 Score =  235 bits (599), Expect = 4e-60,   Method: Compositional matrix adjust.
 Identities = 149/381 (39%), Positives = 210/381 (55%), Gaps = 20/381 (5%)

Query: 122 GYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGV 181
           G+   DG VG +N + I  ++ C       V K+           VDG V + H +GC  
Sbjct: 7   GFSRQDGQVGIRNHVLILPTIVCATQAAQNVTKL-----------VDGTVSVIHQHGC-- 53

Query: 182 AINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIV 241
           A          RT   + LN N  G V+V+GLGCE  Q + +          PVE   +V
Sbjct: 54  AQVGSDYEQTFRTYVGMGLNANVYG-VVVMGLGCETHQGKSVAEEIAKKSNKPVE---LV 109

Query: 242 SLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANP 301
           S+QD  + G      +  +IA + +Q  +  +RE    S+L+VG +CGGSDA SG++ANP
Sbjct: 110 SIQD--YGGTLQATCEAARIATKMVQDASMLEREPIAFSDLIVGTECGGSDACSGLSANP 167

Query: 302 AVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNY-LNMGK 360
           AVGY SD +   G T + +E TE+  A HLL  RA N+ V KR+ E +E  +N    MG 
Sbjct: 168 AVGYVSDAIADYGGTSILAETTELIGAEHLLAGRAANDHVAKRVYEVIEAMENRAYQMGV 227

Query: 361 TDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDF 420
             R+ NPSPGNK+GGL  + EK+LG+ AK+G   + E++   +RPTK+GL++  TP  D 
Sbjct: 228 DIRTGNPSPGNKQGGLTTLEEKSLGAAAKAGTRTLHEIVDYAKRPTKKGLVWMDTPGHDI 287

Query: 421 VCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEE 480
              T   A G  + +FT+GRGTP G    PVIK+AT T +  +  + +D NAGTI  G+E
Sbjct: 288 EQLTGMTAGGAQLVLFTSGRGTPTGSPIAPVIKIATNTAMFEKMNENIDFNAGTIIEGKE 347

Query: 481 TIEEVGWKLFHFILDVASGKK 501
           +IE  G +L   +  VASGK+
Sbjct: 348 SIESTGERLLAEVAAVASGKR 368


>UniRef50_C6J327 Altronate dehydratase n=1 Tax=Paenibacillus sp. oral taxon 786 str.
           D14 RepID=C6J327_9BACL
          Length = 494

 Score =  232 bits (591), Expect = 3e-59,   Method: Compositional matrix adjust.
 Identities = 160/476 (33%), Positives = 248/476 (52%), Gaps = 45/476 (9%)

Query: 16  IKVHDTDNVAIIVNDNGLKAGTRF---PDGLELIEHIPQGHKVALLDIPANGEIIRYGEV 72
           +K++  DNV + +    + AG       + +   + IPQGHK+AL  IPA   + +YG  
Sbjct: 44  MKMNPRDNVGVALQP--ITAGEELQLNEESVRAAQDIPQGHKIALTAIPAGSSVTKYGYS 101

Query: 73  IGYAVRAIPRGSWI-----------DESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFE 121
           IG+ V AI  G W+           +E  V  P   P+            + P   +TF+
Sbjct: 102 IGHVVTAIAPGEWVHTHNIRTNLAGEEQYVYQPNLHPV------------IYPKRSFTFQ 149

Query: 122 GYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGV 181
           GYR A+G  G +N L I  +V CV G+ + +++  + +  P     D +  L+H YGC  
Sbjct: 150 GYRRANGKTGIRNDLYIVPTVGCVNGIAEQMIRAFKAEH-PDLGPFDNITVLSHPYGCSQ 208

Query: 182 AINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEK--LQPERLLTGTDDVQAIPVESAS 239
                  ++    + +  L+PN GG V+V GLGCE   +   R   G  D Q +    A 
Sbjct: 209 L--GEDHLMTRSILADTVLHPNAGG-VLVFGLGCENNVVSEFRERLGHYDEQRVKFLVAQ 265

Query: 240 IVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTA 299
            V  +DE   G  +++E++++ A       N R RE  P SE+ VG++CGGSD+FSG+TA
Sbjct: 266 EV--EDELEAGL-ALLEELVEAAR------NDR-REPVPLSEMNVGLKCGGSDSFSGITA 315

Query: 300 NPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMG 359
           NP +G  SD L+  G + + +EV E+  A  +L  RA ++EV ++++  +  +  Y    
Sbjct: 316 NPLLGAFSDFLISQGGSTILTEVPEMFGAEKMLMARAESQEVFEQIVVLINDFKQYFLFY 375

Query: 360 KTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASD 419
                 NPSPGNK GG++ + +K+LG   K+G + +V+VL  G++  K+GL    TP +D
Sbjct: 376 GEPVYENPSPGNKAGGISTLEDKSLGCTQKAGTAPVVDVLKYGEKLRKKGLSLLQTPGND 435

Query: 420 FVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTI 475
            V  +   A+   + +FTTGRGTP+G   VP +K+AT  EL  R    MD NAG +
Sbjct: 436 LVASSALAAADCQLVLFTTGRGTPFGSF-VPTVKVATNNELFARKQHWMDFNAGVL 490


>UniRef50_A7Z3M9 UxaA n=20 Tax=Bacteria RepID=A7Z3M9_BACA2
          Length = 497

 Score =  231 bits (588), Expect = 6e-59,   Method: Compositional matrix adjust.
 Identities = 163/506 (32%), Positives = 264/506 (52%), Gaps = 23/506 (4%)

Query: 16  IKVHDTDNVAIIVN--DNGLKAGTRFPDGL--ELIEHIPQGHKVALLDIPANGEIIRYGE 71
           IK+H  DNV + +   D G +  T   DGL  E+ + + +GHK+AL  I  NG II+YG 
Sbjct: 5   IKIHKNDNVLLAMRHFDKGERLHT---DGLTIEVKDPVKRGHKIALQTIEENGSIIKYGF 61

Query: 72  VIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVG 131
            IG A R I  G  I  +  +      +     + +  +     E  TF+GYR  +G+ G
Sbjct: 62  SIGRATRRISAGEHI-HTHNLQTNLSDVQEYTYSPRFEDNPFTNENRTFKGYRRENGTSG 120

Query: 132 TKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVP 191
            +N L I  +V CV GV + +++   ++     P  D V+ L H YGC    +       
Sbjct: 121 VRNELWIVPTVGCVNGVAEKILQRFVKEAKDIAP-FDNVLVLKHQYGCSQLGDDHENTKQ 179

Query: 192 IRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGF 251
           +  + N   +PN GG V+V+GLGCE  +   +     +V    V+     ++ DE   G 
Sbjct: 180 M--LMNAIRHPNAGG-VLVLGLGCENNELAAIKETLSEVNGDRVKFLESQAVTDEIEAG- 235

Query: 252 QSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLV 311
            +++++I      HL     + RE  P SEL +G++CGGSD FSG+TANP +G  SD L+
Sbjct: 236 TALLKEI------HLAAKGDK-REEIPLSELSIGLKCGGSDGFSGITANPLLGRFSDYLI 288

Query: 312 RCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGN 371
             G + + +EV E+  A  +L  RA +EEV  + +  +  +  Y    +     NPSPGN
Sbjct: 289 AQGGSTVLTEVPEMFGAETILMQRAASEEVFHKTVRLINDFKQYFMKHEQPIYENPSPGN 348

Query: 372 KKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGI 431
           K+GG++ + +K+LG   K+G + + +VL+ G+    +GL   + P +D +  +   A+G 
Sbjct: 349 KEGGISTLEDKSLGCTQKAGLAPVSDVLTYGETLKTKGLTLLSAPGNDLIASSALAAAGC 408

Query: 432 TVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFH 491
            + +FTTGRGTP+G   VP +K++T T+L       +D NAG +A  + T + +      
Sbjct: 409 HIVLFTTGRGTPFGTF-VPTVKVSTNTDLFQSKPHWIDYNAGRLAEDQTTEDHIVRDFIQ 467

Query: 492 FILDVASGKKKTFSDQWGLHNQLAVF 517
           +I+ VASG  +  +++     +LA+F
Sbjct: 468 YIIKVASG--EFVNNEKNDFRELAIF 491


>UniRef50_B0T3J7 Altronate dehydratase n=15 Tax=Bacteria RepID=B0T3J7_CAUSK
          Length = 514

 Score =  220 bits (561), Expect = 9e-56,   Method: Compositional matrix adjust.
 Identities = 154/454 (33%), Positives = 236/454 (51%), Gaps = 19/454 (4%)

Query: 49  IPQGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLH-TLPLATK 107
           IP+GHK+A+       ++++YG  IG A   I  G  +    V    +   H T      
Sbjct: 59  IPKGHKIAVRAARLGEDLLKYGWPIGRATADIAVGDHVHVHNVETRLSGVEHFTYTAGHP 118

Query: 108 VPEPLPPLEGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNV 167
            P   PPL   TF GYR  +G VGT+N + +  +V CVA   +   +I E+        +
Sbjct: 119 EPRQAPPLA--TFLGYRRKNGRVGTRNEIWVLCTVGCVA---NTARRIAEKANARFAGRI 173

Query: 168 DGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGT 227
           DGV    H +GC    +       +  I  ++ +PN GG V+++GLGCE  Q + LL   
Sbjct: 174 DGVFAFPHPFGCSQLGDDLTHTRKL--IAGLAAHPNAGG-VLILGLGCENNQLKALLESA 230

Query: 228 DDVQAIPVESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQ 287
             +    + S +   ++DE   G  + +E +++IAER        +RE  P S+LV+G++
Sbjct: 231 PGLDPERLRSFTTQMVEDELEDGLDA-IEALVEIAERD-------RREPMPLSDLVIGLK 282

Query: 288 CGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLE 347
           CGGSD FSGVTANP VG  +D +   G T + +E+ EV  A  +L  RA   +V  + + 
Sbjct: 283 CGGSDGFSGVTANPLVGRIADKVSNAGGTPVLTEIPEVFGAEGVLLARAATRQVFDQAVG 342

Query: 348 EMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTK 407
            ++ +  Y          NPSPGN  GG+  + EK+LG++ K G+S +VEVL  G++   
Sbjct: 343 VIDDFKRYFIDNHQPIYENPSPGNIAGGITTLEEKSLGAVQKGGRSMLVEVLRYGEQVGS 402

Query: 408 RGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDL 467
            GL     P +D V  T   A+G TV +FTTGRGTP G  A P +K+A+ + LA R    
Sbjct: 403 HGLTLLEAPGNDAVSSTALTAAGATVILFTTGRGTPLGFPA-PTLKIASNSALAARKPGW 461

Query: 468 MDINAGTIATGEETIEEVGWKLFHFILDVASGKK 501
           +D +AG + +G +T++     L   ++  ASG++
Sbjct: 462 IDFDAGVVLSG-QTMDAAADSLMDLVVATASGQQ 494


>UniRef50_B0K1I9 Altronate dehydratase n=10 Tax=Firmicutes RepID=B0K1I9_THEPX
          Length = 389

 Score =  215 bits (547), Expect = 3e-54,   Method: Compositional matrix adjust.
 Identities = 139/382 (36%), Positives = 208/382 (54%), Gaps = 20/382 (5%)

Query: 120 FEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGC 179
            + Y+  DG  G +N + I  SV C     +   ++I          V G   + +  GC
Sbjct: 3   IKAYKRPDGKYGIRNKVLILPSVGCA----NETARLISEQ-------VQGTTYITNPKGC 51

Query: 180 GVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESAS 239
           G  I +   ++  RT+  ++LNPN  G ++V GLGCE +Q   L          PVE   
Sbjct: 52  G-QIGSSVELMH-RTLIGLTLNPNVYGTIIV-GLGCETIQAYDLYEEVKKRSNKPVE--- 105

Query: 240 IVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTA 299
           ++S+Q E   G    ++  +++A + ++++++ +RE    S + +   CGGSDA SG+ A
Sbjct: 106 VISIQREG--GTLKTIQKGIKLARKMVEEMSKIEREEVDISNITLATNCGGSDATSGIAA 163

Query: 300 NPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDN-YLNM 358
           NP +GY SD+L++ GATV   E TE   A H+L  RA NE+V   LL  ++  +N ++ +
Sbjct: 164 NPTLGYCSDILIKEGATVFLGETTEFIGAEHILARRAKNEKVRNNLLTIVKNLENEFIRL 223

Query: 359 GKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPAS 418
           G   R ANPSPGN KGGL+ + EK+LGSI K G S I EV+  G+ P ++GLI   TP  
Sbjct: 224 GIDVRGANPSPGNIKGGLSTLEEKSLGSIMKGGTSIINEVVRYGEIPKEKGLIIMDTPGY 283

Query: 419 DFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATG 478
           D    T  VA G  + VFTTGRGTP G   +P+IK+    +      D +D++   I  G
Sbjct: 284 DIESVTGMVAGGAQICVFTTGRGTPIGNPIIPLIKITGNKQTYENMSDNIDLDVSDIIEG 343

Query: 479 EETIEEVGWKLFHFILDVASGK 500
           ++ I+E G  L   I+DV +GK
Sbjct: 344 KKDIKECGEMLLQEIIDVCNGK 365


>UniRef50_P42604 Altronate hydrolase n=77 Tax=Bacteria RepID=UXAA_ECOLI
          Length = 495

 Score =  214 bits (545), Expect = 6e-54,   Method: Compositional matrix adjust.
 Identities = 163/512 (31%), Positives = 248/512 (48%), Gaps = 34/512 (6%)

Query: 15  YIKVHDTDNVAIIVNDNGLKAGTRFP---DGLELIEHIPQGHKVALLDIPANGEIIRYGE 71
           YIK+H  DNVA+ + D  L  GT        + L + + +GHK AL DI     +I+YG 
Sbjct: 3   YIKIHALDNVAVALAD--LAEGTEVSVDNQTVTLRQDVARGHKFALTDIAKGANVIKYGL 60

Query: 72  VIGYAVRAIPRGSWID--ESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGS 129
            IGYA+  I  G  +    +   L +       P    +P      E    + YR A+G 
Sbjct: 61  PIGYALADIAAGVHVHAHNTRTNLSDLDQYRYQPDFQDLPAQAADRE---VQIYRRANGD 117

Query: 130 VGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPN---VDGVVGLNHLYGCGVAINAP 186
           VG +N L I  +V CV G+     + I+   L +  N    DGV   +H YGC    +  
Sbjct: 118 VGVRNELWILPTVGCVNGIA----RQIQNRFLKETNNAEGTDGVFLFSHTYGCSQLGDDH 173

Query: 187 AAVVPIRT-IHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQD 245
              +  RT + N+  +PN  G V+VIGLGCE  Q         D+    V         D
Sbjct: 174 ---INTRTMLQNMVRHPN-AGAVLVIGLGCENNQVAAFRETLGDIDPERVHFMICQQQDD 229

Query: 246 EKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGY 305
           E   G    +E + Q+       +   +RE    SEL  G++CGGSD  SG+TANP +G 
Sbjct: 230 EIEAG----IEHLHQL----YNVMRNDKREPGKLSELKFGLECGGSDGLSGITANPMLGR 281

Query: 306 ASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSA 365
            SD ++  G T + +EV E+  A  LL     +E   ++L+  +  +  Y          
Sbjct: 282 FSDYVIANGGTTVLTEVPEMFGAEQLLMDHCRDEATFEKLVTMVNDFKQYFIAHDQPIYE 341

Query: 366 NPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQ 425
           NPSPGNK GG+  + +K+LG   K+G S +V+VL  G+R    GL   + P +D V  + 
Sbjct: 342 NPSPGNKAGGITTLEDKSLGCTQKAGSSVVVDVLRYGERLKTPGLNLLSAPGNDAVATSA 401

Query: 426 QVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEV 485
              +G  + +F+TGRGTPYG   VP +K+AT +ELA +    +D +AG +  G + + ++
Sbjct: 402 LAGAGCHMVLFSTGRGTPYGGF-VPTVKIATNSELAAKKKHWIDFDAGQLIHG-KAMPQL 459

Query: 486 GWKLFHFILDVASGKKKTFSDQWGLHNQLAVF 517
             +    I++ A+GK+    ++     +LA+F
Sbjct: 460 LEEFIDTIVEFANGKQT--CNERNDFRELAIF 489


>UniRef50_C7PV23 Altronate dehydratase n=13 Tax=Bacteria RepID=C7PV23_CHIPD
          Length = 554

 Score =  210 bits (535), Expect = 8e-53,   Method: Compositional matrix adjust.
 Identities = 167/539 (30%), Positives = 247/539 (45%), Gaps = 59/539 (10%)

Query: 16  IKVHDTDNVAIIVNDNGLKAGTRFPDG---LELIEHIPQGHKVALLDIPANGEIIRYGEV 72
           +KVH  DNV + + D  LK G    +      L E +P  HK     +     I  YG +
Sbjct: 9   LKVHPQDNVVVALTD--LKKGESVQENGRVYTLAEDVPAKHKFTETILHPGDAITMYGVL 66

Query: 73  IGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGY---TFEGYRNADGS 129
           +G A   +P G+ I    V    A     L    K    +P +  +   TF GY  ADGS
Sbjct: 67  VGKAKELLPAGAKIAVGNV--QHASSDFQLAATRKTAWHIPDISKWQDRTFMGYHRADGS 124

Query: 130 VGTKNLLGITTSVHCVAGVVDYVVKIIERDL---LPK----------------------- 163
           VGT N   +   V C    V+ + + +  +L    PK                       
Sbjct: 125 VGTGNYWLVIPMVFCENRNVEVLRETLVEELGYGRPKKYAAFARQLAQQYQQGADASAIL 184

Query: 164 ----------------YPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGE 207
                           + NVDG+  L H  GCG  I   A  +       I+ + N  G 
Sbjct: 185 ETVYTEDPAQQGQQRLFENVDGIKFLTHEGGCG-GIRQDAQTLCGLLAGYIT-HANVAG- 241

Query: 208 VMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGF-QSMVEDILQIAERHL 266
             V+ LGC+  Q   L    ++++    + +  + + D++  G  Q+++   ++     L
Sbjct: 242 ATVLSLGCQNAQITML---EEEIRKRSPDFSKPLFILDQQQTGTEQALITAAVRQTMAGL 298

Query: 267 QKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVR 326
            + N+  R   P  +L +G++CGGSD FSG++ANPA+GY SDLLV  G +V+ SE  E+ 
Sbjct: 299 IEANKITRTPAPLYKLCIGLECGGSDGFSGISANPAIGYTSDLLVALGGSVILSEFPELC 358

Query: 327 DAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGS 386
                ++ R VN     R +E M  Y        +    NPSPGN K GL     K+ G+
Sbjct: 359 GVEQEMSDRCVNTTDALRFIELMRTYQRRAEEAGSGFDMNPSPGNIKDGLITDAIKSAGA 418

Query: 387 IAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGL 446
             K G S +  VL   Q+ +  GL    TP +D    T +V +G T+ +FTTG GTP G 
Sbjct: 419 AKKGGTSPVAAVLDYPQKVSLPGLNLLCTPGNDVESTTAEVGAGATIVLFTTGLGTPTGN 478

Query: 447 MAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFS 505
              PVIK+++ T+L  R  D++DIN GTI  GEE+I E G ++ ++++DVASG  K  S
Sbjct: 479 PVTPVIKLSSNTKLYQRMPDIIDINTGTIIDGEESIPEAGERILNYVIDVASGITKARS 537


>UniRef50_A0M231 Altronate hydrolase n=9 Tax=Bacteria RepID=A0M231_GRAFK
          Length = 553

 Score =  210 bits (535), Expect = 9e-53,   Method: Compositional matrix adjust.
 Identities = 170/542 (31%), Positives = 247/542 (45%), Gaps = 70/542 (12%)

Query: 15  YIKVHDTDNVAIIVNDNGLK-----AGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRY 69
           Y ++   DN+ + + D         AG  FP    L E I Q HK AL D     EII Y
Sbjct: 8   YSQIDTRDNIIVAIQDLPKSTIVNIAGKDFP----LEEAIKQKHKFALYDFQIGDEIIMY 63

Query: 70  GEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYT---FEGYRNA 126
           G ++G A++ I RG+ I    +    A         +K     P +  YT   F+GY  A
Sbjct: 64  GVLVGEAIQPIKRGAAITTKNIKHASA---EFNSEQSKYKWTAPDISKYTERTFKGYHRA 120

Query: 127 DGSVGTKNLLGITTSVHCVAGVVDYVV--------------------KIIER-------- 158
           DGSVGT+N   +   V C    +D V                     K+IE+        
Sbjct: 121 DGSVGTRNYWLVIPLVFCENRNIDVVQDALMEALGYQTNKDYSVDTPKLIEKYKNGASPE 180

Query: 159 -----------DLLPK---YPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNF 204
                      + L K   +PNVDG+  L H  GCG  I   +  +  R +     N N 
Sbjct: 181 ELMETSIVHTTEELTKNRLFPNVDGIKFLKHDGGCG-GIRQDSETL-CRLLAGYITNSNV 238

Query: 205 GGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASI---VSLQDEKHVGFQ-SMVEDILQ 260
            G   ++ LGC+  Q + L        AI  +  +    V   +++ +G +   +E  ++
Sbjct: 239 AG-ATILSLGCQNAQMDMLQN------AIAEKDKNFQKPVYYLEQQQIGNERKFIETAVK 291

Query: 261 IAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFS 320
                L + N+  R+    ++LV+G++CGGSD FSG++ N A+GYASDLL   G + + S
Sbjct: 292 KTFIGLSQTNKIDRKPAALNKLVLGLECGGSDGFSGISCNSALGYASDLLTALGGSPVLS 351

Query: 321 EVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVV 380
           E  E+      L  R   +E  ++    M  Y        +    NPSPGN K GL    
Sbjct: 352 EFPELNGVEQELINRCNEKEDAEKFANIMNRYSQRAKDVGSGFENNPSPGNIKDGLITDA 411

Query: 381 EKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGR 440
            K+ G+  K G S +  VL   ++    GL    TP +D    T    SG  + VFTTG 
Sbjct: 412 MKSAGAAKKGGTSPVTSVLDYTEKVKTPGLNLLCTPGNDVESTTGLAGSGCNMIVFTTGL 471

Query: 441 GTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGK 500
           GTP G    PV+KM++ T L  R  D++DINAGT+ TGE+TI+ +G K+   I+ VASG+
Sbjct: 472 GTPTGNPVAPVLKMSSNTALFERMNDIIDINAGTVITGEDTIQSMGEKILDEIILVASGE 531

Query: 501 KK 502
           K+
Sbjct: 532 KE 533


>UniRef50_B5FMP6 Hydrolase, UxaA family n=75 Tax=cellular organisms
           RepID=B5FMP6_SALDC
          Length = 408

 Score =  210 bits (535), Expect = 1e-52,   Method: Compositional matrix adjust.
 Identities = 139/404 (34%), Positives = 219/404 (54%), Gaps = 23/404 (5%)

Query: 119 TFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYG 178
           TF G+R  DG  G +N + I  +  C     + V + I R        V G   +N+ +G
Sbjct: 25  TFLGFRRPDGRFGIRNYVLILPTSVCA----NKVARDIAR-------QVKGATWVNNDFG 73

Query: 179 CGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESA 238
           C     A  A +  +T+ N++ NPN G  ++V+GLGCE  +P R+    +++ A   +  
Sbjct: 74  CCQV--AGDARLTEKTLINVANNPNVGA-IVVVGLGCEGAEPLRI---AEEITAFG-KPT 126

Query: 239 SIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVT 298
           S +++Q+E   G        + +A  + Q+L+ ++ +  P SEL++ M+CGGSD  SG+ 
Sbjct: 127 SCITIQEEG--GTLKCQARGISLARDYAQQLSMQKPQQAPVSELLLAMECGGSDTTSGLA 184

Query: 299 ANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLN- 357
           +NP+ G ASD L+RCG + + SE TE   A H++  RAV  EVG++L++ +   +     
Sbjct: 185 SNPSCGVASDKLIRCGGSSILSETTEFIGAEHVMAKRAVTPEVGQQLIDLVVGCEARAKA 244

Query: 358 MGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPA 417
           +G+  R   P+PGN KGGL  + EK+LG + K+G + +  VL     PT  GL    TP 
Sbjct: 245 LGEDIRGGQPTPGNIKGGLTTIEEKSLGCMHKAGHAPLQGVLEYADSPTHPGLWIMDTPG 304

Query: 418 SDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIAT 477
            D    +  VA G  + +FTTGRGTP G    PVIK+           D +DI+   I +
Sbjct: 305 QDIESISGMVAGGAQIVIFTTGRGTPAGNPIAPVIKITGNKATWEMMQDNIDIDVSAIMS 364

Query: 478 GEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAP 521
           GE +I ++G +++  IL VA+G K T S+  G HN+ +++  AP
Sbjct: 365 GEASITQMGEEIYQEILRVANG-KTTKSEDLG-HNEFSIYKIAP 406


>UniRef50_C4X086 Altronate hydrolase n=14 Tax=Bacteria RepID=C4X086_KLEPN
          Length = 495

 Score =  209 bits (533), Expect = 2e-52,   Method: Compositional matrix adjust.
 Identities = 167/514 (32%), Positives = 260/514 (50%), Gaps = 38/514 (7%)

Query: 15  YIKVHDTDNVAIIVNDNGLKAGTRFP---DGLELIEHIPQGHKVALLDIPANGEIIRYGE 71
           YIK+H  DNVA+ + D  + AG+      D + L + I +GHK AL  I     +++YG 
Sbjct: 3   YIKIHSQDNVAVALTD--IAAGSVVTIDNDSVTLGQDIVRGHKFALRAIAKGENVVKYGL 60

Query: 72  VIGYAVRAIPRGSWID--ESMVVLPEAPPLHTLP-LATKVPEPLPPLEGYTFEGYRNADG 128
            IG+A+  I  G  +    +   L +       P L  + P+P         + YR A+G
Sbjct: 61  PIGHALADIAPGEHVHAHNTRTNLSDLDAYRYQPDLVAQPPQPAD----REVQIYRRANG 116

Query: 129 SVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKY--PNVDGVVGLNHLYGCGVAINAP 186
            VG +N L I  +V CV  +     ++  R L   Y   ++DGV   +H YGC    +  
Sbjct: 117 DVGVRNELWILPTVGCVNAMAR---QMQNRFLKETYGAEDIDGVHLFSHTYGCSQLGDDH 173

Query: 187 AAVVPIRT-IHNISLNPNFGGEVMVIGLGCEKLQPE--RLLTGTDDVQAIPVESASIVSL 243
              +  RT + N+  +PN  G V+V+GLGCE  Q E  R   G  D Q +      +   
Sbjct: 174 ---INTRTMLQNMVRHPN-AGAVLVVGLGCENNQVEAFRETLGEFDPQRVHF---MVCQH 226

Query: 244 QDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAV 303
           QD++    ++ VE + Q+ E     + Q +R+    SEL  G++CGGSD  SG+TANP +
Sbjct: 227 QDDE---VEAGVEHLHQLYE----VMRQDKRQPGKLSELKFGLECGGSDGLSGITANPML 279

Query: 304 GYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDR 363
           G  SD ++  G T + +EV E+  A  LL     +E    +L+  +  +  Y        
Sbjct: 280 GRFSDYVIANGGTTVLTEVPEMFGAEQLLMSHCRDEATFDKLVTMVNDFKQYFIAHDQPI 339

Query: 364 SANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCG 423
             NPSPGNK GG+  + +K+LG   K+G S +V+VL  G+R    GL   + P +D V  
Sbjct: 340 YENPSPGNKAGGITTLEDKSLGCTQKAGSSQVVDVLRYGERLKVHGLNLLSAPGNDAVAT 399

Query: 424 TQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIE 483
           +    +G  + +F+TGRGTPYG   VP +K+AT +ELA +    +D +AG +  G +T+ 
Sbjct: 400 SALAGAGCHMVLFSTGRGTPYGGF-VPTVKIATNSELAAKKKHWIDFDAGQLLHG-KTMP 457

Query: 484 EVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVF 517
           ++  +    I+  A+G K T ++Q     +LA+F
Sbjct: 458 QLLEEFVDAIVAFANG-KPTCNEQNDF-RELAIF 489


>UniRef50_Q6L323 Altronate hydrolase n=1 Tax=Picrophilus torridus RepID=Q6L323_PICTO
          Length = 393

 Score =  198 bits (503), Expect = 5e-49,   Method: Compositional matrix adjust.
 Identities = 128/384 (33%), Positives = 207/384 (53%), Gaps = 19/384 (4%)

Query: 120 FEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVG-LNHLYG 178
           F GY  ++G  GT+N + I  +V C     ++ V+ I R+ L  Y N DG +  LN+ YG
Sbjct: 5   FLGYERSNG-FGTRNHILIIPTVTCS----EFTVRRIARESLKYYNNPDGSIKVLNNPYG 59

Query: 179 CGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESA 238
           CG            RT+ N+ +NPN  G V+V+ LGCE +   ++    D++     +  
Sbjct: 60  CGQT--GEDLEQTTRTLINMGINPNVSG-VLVLSLGCESVDYNKV---ADEISK--YKPV 111

Query: 239 SIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVT 298
           + + +QD  + G +++   I +I +     + +++ ET     +  G++CGGSD  SG+ 
Sbjct: 112 NFLRIQD--YGGLKTVETGIEKIKDLAANAIKEKRNET-DLKNITAGLECGGSDFTSGLA 168

Query: 299 ANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNM 358
           +NP VG  SD ++  G + + SEV E   A HL   RAVNE+V  ++ + +  ++  L  
Sbjct: 169 SNPVVGKVSDWIINNGGSTIISEVPEFIGAEHLYAARAVNEDVRAQIFKTVYAFEKKLKE 228

Query: 359 -GKTD-RSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATP 416
             + D R   P+PGN +GGL  + EK+LG++ KSG + +  VL  G+R +K G     TP
Sbjct: 229 EARVDFRKGQPTPGNMEGGLTTIEEKSLGAVKKSGSAKVSGVLKYGERLSKPGHYLMNTP 288

Query: 417 ASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIA 476
             D    + +VA G  + +FTTGRGTP G +  PVIK+    E   +  D++D +A  I 
Sbjct: 289 GYDVESVSGEVAGGANIVMFTTGRGTPTGNIISPVIKITANEETFKKMEDIIDFDASPIM 348

Query: 477 TGEETIEEVGWKLFHFILDVASGK 500
            G+ETIE    +L   +++ A+G+
Sbjct: 349 RGDETIESASERLKKLLIETANGR 372


>UniRef50_C9KKM7 Hydrolase, UxaA family n=1 Tax=Mitsuokella multacida DSM 20544
           RepID=C9KKM7_9FIRM
          Length = 352

 Score =  197 bits (502), Expect = 6e-49,   Method: Compositional matrix adjust.
 Identities = 126/341 (36%), Positives = 181/341 (53%), Gaps = 8/341 (2%)

Query: 173 LNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQA 232
           +N ++  G +  A    +  + +   + NPN  G V++IGLGCE +    L      + +
Sbjct: 9   VNIVFNTGCSDVAANTAMSQKVLTGFACNPNVYG-VVIIGLGCETVPHAALREKIQKMTS 67

Query: 233 IPVESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSD 292
            PV S  I   QDE   G    +E  ++ A    Q+   +Q+E  PASEL++G++CGGSD
Sbjct: 68  KPVVSFGI---QDEG--GTLKTIEKAVRAARDMAQQAGMQQKELFPASELLLGIECGGSD 122

Query: 293 AFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWY 352
           A SG+  NPAVG  SD+LV  GA+ M SE  E     H+L  RA   E+ + ++   E Y
Sbjct: 123 ATSGIACNPAVGELSDILVDMGASAMMSESIEWIGGEHVLAKRAATPEIQREIIRVCEEY 182

Query: 353 DNYL-NMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLI 411
           + +L   G+  R+  P+PGNK GGL+ + EK+LG I K G   IVEVL    RPTKRG +
Sbjct: 183 EKHLAGAGQDCRAGQPTPGNKAGGLSTLDEKSLGCIRKGGTRPIVEVLEQAVRPTKRGAL 242

Query: 412 YAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDIN 471
              T   D    T   A+G  V +FTTGRGTP G   VPV+K+           D MD +
Sbjct: 243 VMDTAGYDISSVTSMAAAGCQVIIFTTGRGTPTGNAIVPVLKVTANARTYRCMEDNMDAD 302

Query: 472 AGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHN 512
              I  GE+T ++ G +L   I   A+G + T ++ +G  +
Sbjct: 303 LSAIVRGEKTYQQAGRELVDAIAATANG-RLTKAEAFGFSD 342


>UniRef50_D0ZBA7 Altronate hydrolase n=15 Tax=Bacteria RepID=D0ZBA7_EDWTE
          Length = 496

 Score =  197 bits (500), Expect = 1e-48,   Method: Compositional matrix adjust.
 Identities = 154/504 (30%), Positives = 241/504 (47%), Gaps = 18/504 (3%)

Query: 16  IKVHDTDNVAIIVNDNGLKAGTRFPDG-LELIEHIPQGHKVALLDIPANGEIIRYGEVIG 74
           IK+H  DNVA+ + D          DG L L + +P+GHKVAL  +     +I+YG  IG
Sbjct: 5   IKIHPQDNVAVALRDLAAGETIALDDGALTLRDAVPRGHKVALCHLAPQAMVIKYGLPIG 64

Query: 75  YAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVGTKN 134
           +A+  I  G  +  +  +      L +         P           YR A G V  +N
Sbjct: 65  HALTPIAAGDHV-HAQNLRTNLSDLDSYQYQPDFAAPTAQPADRAISLYRRASGEVAIRN 123

Query: 135 LLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRT 194
            L I  +V CV G+   +++   R+       +DGV    H +GC    +       +  
Sbjct: 124 ELWILPTVGCVNGMARQMLQRFLRES-DGASAIDGVHLFTHPFGCSQLGDDHQNTRTL-- 180

Query: 195 IHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSM 254
           + N+  +PN GG V+V+GLGCE  Q         D     V         DE   G +++
Sbjct: 181 LQNMVHHPNAGG-VLVVGLGCENNQIAAFRETLGDYDPARVRFLVCQQQDDEVEAGTEAL 239

Query: 255 VEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCG 314
            E  L  A R        +RE    SEL  G++CGGSD FSG++ANP +G  SD ++  G
Sbjct: 240 HE--LYGAMR------GDRREPGRLSELKFGLECGGSDGFSGISANPLLGRFSDYVIAHG 291

Query: 315 ATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKG 374
            T + +EV E+  A  +L  R  + E  ++ +  +  +  Y    +     NPSPGNK G
Sbjct: 292 GTSVLTEVPEMFGAERILMSRCRDGETFEKTVAMVNDFKRYFIDHQQPIYENPSPGNKAG 351

Query: 375 GLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQ 434
           G+  + EK+LG   K+G+S +++VL  G+R    GL   + P +D V  +   A+G  + 
Sbjct: 352 GITTLEEKSLGCTQKAGQSQVMDVLRYGERLHTPGLNLLSAPGNDAVATSALAAAGCHMV 411

Query: 435 VFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFIL 494
           +F+TGRGTPYG   VP +K+AT T LA +    +D +AG +  G + +  +  +    I+
Sbjct: 412 LFSTGRGTPYGGF-VPTVKLATNTPLAAKKPHWIDFDAGQLLQG-KPMALLLSEFIDLIV 469

Query: 495 DVASGKKKTFSDQWGLHNQLAVFN 518
            +A G++    ++     +LA+F 
Sbjct: 470 AIADGRQTC--NEKNDFRELAIFK 491


>UniRef50_D1Y174 D-galactarate dehydratase (GalcD) n=3 Tax=Bacteria
           RepID=D1Y174_9BACT
          Length = 386

 Score =  192 bits (489), Expect = 2e-47,   Method: Compositional matrix adjust.
 Identities = 134/394 (34%), Positives = 193/394 (48%), Gaps = 21/394 (5%)

Query: 120 FEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGC 179
           F GY+  +G  G +N + I  +  C +     V              V G V  N ++  
Sbjct: 3   FWGYKRQEGRAGIRNHVLILPTCACGSESARIVA-----------SEVRGAV--NIIFNT 49

Query: 180 GVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESAS 239
           G +  A    +  + +   + NPN  G V++IGLGCE +   +L      +   PV    
Sbjct: 50  GCSDVAANTAMSQKVLMGFACNPNVYG-VVIIGLGCETVGHAQLREKIRGMTGKPV---- 104

Query: 240 IVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTA 299
            VS   ++  G    +E  ++ A         +Q+E C  S L++G++CGGSDA SG+ +
Sbjct: 105 -VSFGIQEEGGTLKTIEKAVRAARDMAAAAAMQQKERCDMSNLLLGIECGGSDATSGIAS 163

Query: 300 NPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMG 359
           NPAVG  SDLLV  GA+ + SE  E   A H++  RA   E+  +++E    Y+ +L   
Sbjct: 164 NPAVGELSDLLVDLGASTIMSESIEWIGAEHVVARRAATPELHNKIIEICRDYEEHLKAA 223

Query: 360 KTD-RSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPAS 418
             D R+  P+PGNK GGL+ + EK+LG I K G   IVEVL+  +RPTK G I   T   
Sbjct: 224 GQDCRAGQPTPGNKAGGLSTLDEKSLGCIRKGGTRPIVEVLAQAERPTKHGAIVMDTAGY 283

Query: 419 DFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATG 478
           D    T  VA G    +FTTGRGTP G   VPV+K+           D MD++   I  G
Sbjct: 284 DISSVTSMVAGGCNAVIFTTGRGTPTGNAIVPVLKVTANARTYRMMDDNMDVDLSGIIKG 343

Query: 479 EETIEEVGWKLFHFILDVASGKKKTFSDQWGLHN 512
             T  E G +L   I DV +G K T ++ +G  +
Sbjct: 344 TTTYRESGRELLEIIGDVCNG-KMTKAEAYGFSD 376


>UniRef50_D2QEC5 Altronate dehydratase n=2 Tax=Sphingobacteriales RepID=D2QEC5_9SPHI
          Length = 582

 Score =  191 bits (485), Expect = 5e-47,   Method: Compositional matrix adjust.
 Identities = 159/552 (28%), Positives = 234/552 (42%), Gaps = 65/552 (11%)

Query: 13  AFYIKVHDTDNVAIIVNDNGLKAGTRFPDGL-ELIEHIPQGHKVALLDIPANGEIIRYGE 71
           A  +KVH  DNV + + +        F + L EL   +   HK    D      I  YG 
Sbjct: 28  ARVLKVHPADNVIVALRNLAAGEKIEFENTLYELPYAVGAKHKFVTEDRQPGDPITMYGV 87

Query: 72  VIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPP-----LEGYTFEGYRNA 126
           ++G A + I RG    E +          T  L  K P    P      EG TF GY  A
Sbjct: 88  LVGKATQPIRRG----EPITTFNLKHDADTYGLDKKQPYSWQPPNTLAWEGRTFMGYHRA 143

Query: 127 DGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYP--------------------- 165
           DGSVGT+N   +   V C    V  +    ER+L    P                     
Sbjct: 144 DGSVGTRNYWLVVPLVFCENRNVLILKDAFERELGYAQPETYRVQVHELLSLYKAGEMDI 203

Query: 166 ----------------------------NVDGVVGLNHLYGCGVAINAPAAVVPIRTIHN 197
                                       NVDG+  L H  GCG        +  +  +  
Sbjct: 204 AKKMQPFVDESQNQTLNSARHQANRPFKNVDGIKFLTHEMGCGGTRQDSGYLCSL--LAG 261

Query: 198 ISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVED 257
              NPN  G   V+ LGC+ LQ +  +   +  +  P     ++  + +    +  M E 
Sbjct: 262 FINNPNVAG-ATVLSLGCQHLQTD--MISAEIKRQNPKFDKPLLLFEQQAGTEYALMSEA 318

Query: 258 ILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATV 317
           + Q     L  +N+ +R+  P S L VG++CGGSD FSG++ANPA+G  SD+LV  G   
Sbjct: 319 VKQTF-LGLVDINKLERQPAPLSALTVGLKCGGSDGFSGISANPALGQLSDILVTLGGKT 377

Query: 318 MFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGLA 377
           + +E  E+      L  R  + +  ++ +  M  Y        +    NPSPGN K GL 
Sbjct: 378 VLAEFPELNGVEQELINRTDDTDKAQKFITLMGDYSAQAEAVGSGFDMNPSPGNIKDGLI 437

Query: 378 NVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFT 437
               K+ G+  K G + + +VL   +  T  GL    TP +D    T    SG  V +FT
Sbjct: 438 TDAIKSAGAAKKGGTAPVADVLDYAEPATTPGLNLLCTPGNDVEATTGMAGSGTNVILFT 497

Query: 438 TGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVA 497
           TG GTP G    PV+K++T T L NR  D++D ++G I  GE++IE+    +  +I+ +A
Sbjct: 498 TGLGTPTGNPVCPVVKVSTNTVLKNRMPDVIDFDSGPIIDGEQSIEQNANAMLEYIIKLA 557

Query: 498 SGKKKTFSDQWG 509
           SG+  T +++ G
Sbjct: 558 SGEVITQAERLG 569


>UniRef50_D1Y193 Galactarate dehydratase n=1 Tax=Pyramidobacter piscolens W5455
           RepID=D1Y193_9BACT
          Length = 408

 Score =  190 bits (483), Expect = 1e-46,   Method: Compositional matrix adjust.
 Identities = 124/393 (31%), Positives = 197/393 (50%), Gaps = 33/393 (8%)

Query: 119 TFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYG 178
           TF GYR +DG+VG +N L I  SV C    V+ +              + G V + H  G
Sbjct: 4   TFNGYRRSDGTVGVRNHLAIIPSVFCANRTVERIA-----------AQLPGSVPIRHAVG 52

Query: 179 C---GVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPV 235
           C   G+ +   A     RT+  +  +PN G  V+VIGLGCE+  P  L       +A+  
Sbjct: 53  CSQVGLDLELTA-----RTLKALGTHPNVGA-VLVIGLGCERFPPREL------EEAVRK 100

Query: 236 ESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFS 295
               +     ++  G  + ++  ++   +    L +++R  CP SEL VG +CGG+DA S
Sbjct: 101 SGRPVACFVIQEEGGTTNTIKHAVEAGRKMFASLAEQRRVPCPLSELFVGTKCGGTDATS 160

Query: 296 GVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNY 355
           G+ ANPAVG   D LV  G + + SE+ E+    H+L  RAV++EV  ++ + +   ++ 
Sbjct: 161 GLAANPAVGEMVDKLVAQGGSAILSEMNELLGTEHILARRAVSKEVADKVYKAIYEIEDV 220

Query: 356 LNMG-----KTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPT--KR 408
           L  G        R+   SPGN  GG++++VEKALG + KSG   IV+V+     P   K+
Sbjct: 221 LRSGIDMRLGAKRNQLISPGNADGGVSSIVEKALGGMHKSGTCPIVDVIDYATPPEKGKK 280

Query: 409 GLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLM 468
           GL      + D    T ++  G  +  FTTGRG+P G    PV+K+    +      ++ 
Sbjct: 281 GLFLMKYESHDGEVTTGEIGCGAQIVAFTTGRGSPTGHPIAPVVKITGNEKTYKAMSEMF 340

Query: 469 DINAGTIATGEETIEEVGWKLFHFILDVASGKK 501
           D +A  I +  +++E+ G  L   ++ VA G++
Sbjct: 341 DFDASGIISRGDSLEDTGRALLDLVIRVADGER 373


>UniRef50_D2S1M0 Altronate dehydratase n=1 Tax=Haloterrigena turkmenica DSM 5511
           RepID=D2S1M0_9EURY
          Length = 395

 Score =  186 bits (473), Expect = 2e-45,   Method: Compositional matrix adjust.
 Identities = 137/394 (34%), Positives = 199/394 (50%), Gaps = 23/394 (5%)

Query: 119 TFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYG 178
           TF GYR  DG +G +N + +  +    + V D +      +  P+      V    H  G
Sbjct: 3   TFSGYRREDGRIGVRNRVAVLPTSVAASAVADRIAA----NGGPR------VTATPHQMG 52

Query: 179 CGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESA 238
                  PA     R +  I  NPN GG  +V+ LG E      +          PVE+ 
Sbjct: 53  --TEQPEPARRRTERVLAGIGRNPNVGG-ALVVELGTEGADASAIAD-EIAAADTPVETL 108

Query: 239 SIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVT 298
           SI         G ++ V+   +  +  L++  + + ET  ASELV G++CGGSDA SG+ 
Sbjct: 109 SI-----RDAGGTRATVDRGRETVDALLEEAARARLETADASELVFGVECGGSDATSGIA 163

Query: 299 ANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLN- 357
           ANPAVG A D LV  G T  FSE  E   A H+L  R V+E V +RL+E +E  ++  + 
Sbjct: 164 ANPAVGNACDRLVEAGGTSCFSETPEFIGAEHILAERCVDESVRERLIECVERRESVADL 223

Query: 358 MGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQ-RPTKRGLIYAATP 416
           MG   R   P+PGN++GGL  + EK+LG+IAK G + I +V+      P   GL+   TP
Sbjct: 224 MGVDLRGTQPTPGNQEGGLTTIEEKSLGAIAKGGTTPIRDVIDYADPLPIGGGLVVMDTP 283

Query: 417 ASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIA 476
             D      +VA G  V  FTTGRG+  G    PVIK+    + A R    MD++A T+ 
Sbjct: 284 GYDVESVVGKVAGGAQVIAFTTGRGSTTGNPIAPVIKVTGNPQTAERMATNMDVDASTVL 343

Query: 477 TGEETIEEVGWKLFHFILDVASGKKKTFSDQWGL 510
            G E++E VG +++  +L VA G  +T +++ G+
Sbjct: 344 DG-ESVEAVGERVYETLLSVADG-TRTEAERRGM 375


>UniRef50_C1NB77 Altronate dehydratase n=2 Tax=Enterobacteriaceae RepID=C1NB77_9ESCH
          Length = 533

 Score =  185 bits (470), Expect = 3e-45,   Method: Compositional matrix adjust.
 Identities = 149/517 (28%), Positives = 239/517 (46%), Gaps = 48/517 (9%)

Query: 16  IKVHDTDNVAIIVNDNGLKAGTRFP---DGLELIEHIPQGHKVALLDIPANGEIIRYGEV 72
           +++   DN+ + + D  L AG  F    D + L+  +   HK A  DIP +G +  YG  
Sbjct: 7   LRIDSNDNLIVALKD--LHAGESFSWDDDNITLVTDVKAKHKFATQDIPLDGIVSMYGTP 64

Query: 73  IGYAVRAIPRGSWID-------ESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRN 125
           +G A R I +G  I         + V L +  P H      + P+ +      TF+GY  
Sbjct: 65  VGKATRPIVKGEAITVDNIRHYAAPVTLEDVEPYHW-----QAPD-VSEWSTRTFKGYVR 118

Query: 126 ADGSVGT--------------KNLLGITTSVHCVAGVVDYVVKIIERDLLP--------- 162
            DG VGT              +N+  +T +++   G  +  +K    +L           
Sbjct: 119 DDGRVGTASYWLVFPLVFCENRNVSKLTNALNDALGYTNNSLKKFALNLTSGSDELIETA 178

Query: 163 -KYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPE 221
             +P+++GV  +    GCG A +    +  +   +  + +PN  G + V  LGCEK Q +
Sbjct: 179 RMFPHIEGVRCITVTSGCGGATSDCETMCDVLAAY--ADHPNVIG-MTVFSLGCEKAQ-Q 234

Query: 222 RLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASE 281
           ++       +    +  ++  LQ E     + M++  LQ     ++ +   +R   P S 
Sbjct: 235 KMFKDALARRNPEFDKPALYFLQQEWD-SEERMMQTALQQTFEAMKAVKPTERVEVPLSC 293

Query: 282 LVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEV 341
           L VGM+CGGSD FSG++ NPA+G  SD L   G     +E  E+  A   +  R +N E 
Sbjct: 294 LKVGMKCGGSDGFSGISGNPAMGLVSDWLTTLGGASGLAEFPELCGAEGDMVKRCINLED 353

Query: 342 GKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSP 401
            K+ L  M+ Y+   N   T  + NPS GN   GL     K+ G+  K G++ IV V   
Sbjct: 354 KKKFLNLMQGYEKTANFFDTTIADNPSFGNIADGLITDAIKSTGAAKKGGRAPIVSVCDY 413

Query: 402 GQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELA 461
            +     GL    TP +D    T  VA+G  V +F+TG GTP G   VPV+K++T + +A
Sbjct: 414 AEPMPDSGLSLVCTPGNDVDAVTGLVAAGCNVVIFSTGLGTPTGNPIVPVLKISTNSTIA 473

Query: 462 NRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVAS 498
            R  D++D + G +  G   +E+V  +LF  +++ AS
Sbjct: 474 RRLSDMIDFDCGPVIDGTP-LEDVSRELFEKVIETAS 509


>UniRef50_C0CW83 Putative uncharacterized protein n=1 Tax=Clostridium asparagiforme
           DSM 15981 RepID=C0CW83_9CLOT
          Length = 387

 Score =  183 bits (464), Expect = 1e-44,   Method: Compositional matrix adjust.
 Identities = 130/408 (31%), Positives = 206/408 (50%), Gaps = 29/408 (7%)

Query: 120 FEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGC 179
           F+GY   DG+VG++NL+ +  SV C   V   +V             V G VGL H  GC
Sbjct: 3   FQGYVRPDGTVGSRNLVAVIPSVVCANDVAQAIV-----------AQVQGTVGLYHHQGC 51

Query: 180 GVAINAPAAVVPI-RTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESA 238
                 P  +  +  T+  +   PN G   +V+ LGCE    ERL      V+ I     
Sbjct: 52  ---CQLPPDLDRVTETLIGLGCGPNVGA-ALVVSLGCEGTDHERL------VEEIARTGK 101

Query: 239 SIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVT 298
            +  ++ ++  G    +   +  A R ++ +  +QR     S++V+ ++CG SD  SG+ 
Sbjct: 102 PVEIIRIQQLGGVSKAIAAGIDAASRLVRAIAPQQRREADISKVVLAIKCGASDTTSGMA 161

Query: 299 ANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYL-N 357
           +N A+GY +D LV  G TV+F E TE   A H+L  RAVN +V  ++ E +   ++   +
Sbjct: 162 SNCALGYVADKLVDLGGTVVFGETTEFLGAEHILKRRAVNAQVADKIDEIVARMESRAKS 221

Query: 358 MGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQR-PTKRGLIYAATP 416
           +G   R   P+PGN +GGL+++ EK+LG+I KSG   I  V+    R   ++GL    TP
Sbjct: 222 LGCDMRKGQPTPGNIEGGLSSIEEKSLGAIVKSGTRPIQGVMEYTDRVGDRKGLWIKDTP 281

Query: 417 ASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIA 476
             +    T    +G  + +F+TGRG P G   +PV+K+           + MDINAG I 
Sbjct: 282 GREPEILTGMACTGAQLMMFSTGRGAPQGFPTMPVVKVCGNPITYRNMENDMDINAGLII 341

Query: 477 TGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLH--NQLAVFNPAPV 522
            G+++IE+VG ++F  I++V +G     S    LH  + + ++   PV
Sbjct: 342 EGKKSIEQVGEEVFEKIVEVLNGG---MSKNESLHYYSSIDIYTLGPV 386


>UniRef50_B8FML6 Altronate dehydratase n=1 Tax=Desulfatibacillum alkenivorans AK-01
           RepID=B8FML6_DESAA
          Length = 386

 Score =  182 bits (462), Expect = 3e-44,   Method: Compositional matrix adjust.
 Identities = 137/386 (35%), Positives = 200/386 (51%), Gaps = 26/386 (6%)

Query: 119 TFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYG 178
           +F GY   DGSVG +N + +  SV C A V   + +            V GVV L H  G
Sbjct: 3   SFMGYGREDGSVGVRNYVAVIPSVACAAPVAAAIAR-----------AVPGVVPLLHGMG 51

Query: 179 CGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESA 238
           CG       A +  RT  N+  NPN G  V+++GLGCE      ++       A  +   
Sbjct: 52  CGRG--GSDADMHTRTFQNLCKNPNVGA-VIIVGLGCE------VVNAEGMALAAAMAGR 102

Query: 239 SIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVT 298
               L  +   G +      + IA+  + ++  ++R+  P  +L +G++CGGSDAFSGVT
Sbjct: 103 PHARLMIQAEGGSRKTTAKGIGIAKDFMTQIQVQERKPFPLDKLTLGLECGGSDAFSGVT 162

Query: 299 ANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVG---KRLLEEMEWYDNY 355
           ANPAVG ASD LV  G  V+ +E TE+    H+L  R+ N E+    K L+  +E    Y
Sbjct: 163 ANPAVGRASDWLVAKGGKVILTETTEMIGTSHILERRSANPEIAEQIKNLISSVEA-KTY 221

Query: 356 LNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAAT 415
             +G   +    SPGN  GG++++ EKALG I K G + I +V+   + PT+ GL     
Sbjct: 222 EVLGPIAKMIM-SPGNMDGGMSSIREKALGCIIKGGTTPINQVVDYAEIPTQPGLSIMHG 280

Query: 416 PASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTI 475
           P  D    T   ASG  V VFTTGRG P G   VPV+K+A+ + +     D MD+NAG I
Sbjct: 281 PGYDAESLTGLAASGAQVIVFTTGRGNPIGFPIVPVVKVASTSRMFQSMEDDMDLNAGAI 340

Query: 476 ATGEETIEEVGWKLFHFILDVASGKK 501
             G ++++++G  +   ILD  +G++
Sbjct: 341 LEG-KSLDQMGEDVVQCILDAVNGRR 365


>UniRef50_UPI0001C34772 Altronate dehydratase n=1 Tax=Providencia rettgeri DSM 1131
           RepID=UPI0001C34772
          Length = 531

 Score =  182 bits (461), Expect = 4e-44,   Method: Compositional matrix adjust.
 Identities = 150/521 (28%), Positives = 239/521 (45%), Gaps = 38/521 (7%)

Query: 16  IKVHDTDNVAIIVNDNGLKAGTRFPDGLE---LIEHIPQGHKVALLDIPANGEIIRYGEV 72
           +K+ ++DN+ + + D  L+AG  +  G E   L+  +   HK A+  IP +G +  YG  
Sbjct: 5   LKIDESDNLIVALKD--LQAGDIYHWGSEEVTLVTDVKAKHKFAMEAIPVDGIVSMYGTA 62

Query: 73  IGYAVRAIPRGSWIDESMVVLPEAPPL--HTLPLATKVPEPLPPLEGYTFEGYRNADGSV 130
           +G A + I +G  I    +    AP       P     P+ +   +G TF+GY   DG V
Sbjct: 63  VGKATKPIAKGEVITVDNIRHYAAPVSLEQDAPYEWNAPD-VSAYQGRTFKGYIREDGRV 121

Query: 131 GTKNLLGITTSVHC--------------VAGVVDYVVKIIERDLL---------PK-YPN 166
           GT N   I   V C                G  +  +K    DL          PK +P+
Sbjct: 122 GTANYWLIFPLVFCENRNVTKLTDALNEALGYTNNSLKNFALDLTAGEQREGAKPKLFPH 181

Query: 167 VDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTG 226
           ++GV  +    GCG A +    +  +   +  + +PN  G + V  LGCEK Q  ++   
Sbjct: 182 IEGVRCITVTSGCGGATSDSKTMCDVLAAY--ADHPNVIG-ITVFSLGCEKAQ-RKMFKE 237

Query: 227 TDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGM 286
           +   +       ++   Q E +   + M++  L+     ++ +  + R   P   L +G+
Sbjct: 238 SLAARNSNFNKPALYFRQQEWN-SEEEMMQTALKQTYECMKAVEPQSRVDVPLFHLKLGV 296

Query: 287 QCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLL 346
           +CG SD FSG++ NPA+G  SD LV  G     +E  E+  A   +  R V+ E  ++ L
Sbjct: 297 KCGASDGFSGISGNPAMGLVSDWLVTLGGASGLAEFPELCGAEGDMVKRCVSFEDKRKFL 356

Query: 347 EEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPT 406
           + ME Y+   N   T  + NPSPGN   GL     K+ G+  K G S I  V    +   
Sbjct: 357 DLMERYEKTANFFNTTIADNPSPGNIADGLITDAIKSTGAAKKGGTSPISAVCDYAEPMP 416

Query: 407 KRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFD 466
             GL    TP +D    T  VA+G  V +F+TG GTP G   VPV+K++T + +A R  D
Sbjct: 417 DSGLSLVCTPGNDVDAVTGLVAAGCNVVIFSTGLGTPTGNPIVPVLKISTNSAIAERLSD 476

Query: 467 LMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQ 507
           ++D + G I  G   +  +   LF  +++ ASG  +  +D+
Sbjct: 477 IIDYDCGPIIDG-VPLPTISKGLFERVIETASGDYQVQADR 516


>UniRef50_C4STJ6 Altronate dehydratase n=1 Tax=Yersinia frederiksenii ATCC 33641
           RepID=C4STJ6_YERFR
          Length = 529

 Score =  171 bits (433), Expect = 6e-41,   Method: Compositional matrix adjust.
 Identities = 145/520 (27%), Positives = 239/520 (45%), Gaps = 38/520 (7%)

Query: 16  IKVHDTDNVAIIVNDNGLKAGTRF---PDGLELIEHIPQGHKVALLDIPANGEIIRYGEV 72
           +K+ ++DN  +IV    L+ G       D   L+  +   HK ++ DI   G +  YG  
Sbjct: 5   LKIDESDN--LIVALKNLQKGETVCWGDDHFTLMTDVKAKHKFSVEDIAIGGIVSMYGTP 62

Query: 73  IGYAVRAIPRGSWIDESMVVLPEAP-PLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVG 131
           +G A + I +G  +    +    AP  L+      + P+ +      TF+GY  +DG VG
Sbjct: 63  VGKATKPIAKGEAVTVDNIKHYAAPVQLNDEQYNWQAPD-ISSYIDRTFKGYLRSDGRVG 121

Query: 132 T--------------KNLLGITTSVHCVAGVVDYVVKIIERDLL----PK-----YPNVD 168
           T              +N+  +T +++   G  D+ +     +L     P+      P+++
Sbjct: 122 TANYWLVFPLVFCENRNVTKLTDALNDALGYSDHSLTRFAMNLAGGDAPQVKEKLLPHIE 181

Query: 169 GVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTD 228
           GV  +    GCG A  A  ++     +   + +PN  G + V  LGCEK Q   ++   D
Sbjct: 182 GVRSITVSSGCGGA--ASDSMTMCEVLAAYADHPNVIG-ITVFSLGCEKAQ---VIDFKD 235

Query: 229 DVQAI-PVESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQ 287
            ++   P  S   +  + ++    + M++  L+     + ++    R   P S L +G++
Sbjct: 236 ALKKCNPQFSKPTLYFKQQEWENEEQMMQSALKETFACMNEVQPTPRVDVPLSHLKLGVK 295

Query: 288 CGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLE 347
           CG SD FSG++ NPA+G  SD +V  G     +E  E+  A   +  R  + E   + L 
Sbjct: 296 CGASDGFSGISGNPAMGLVSDWVVTLGGASALAEFPELCGAEGDMVKRCRHPEDKSKFLS 355

Query: 348 EMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTK 407
            M  Y+   N   T  + NPSPGN   GL     K+ G+  K G++ I  V    +    
Sbjct: 356 LMAGYEKTANFFNTSIADNPSPGNIADGLITDAIKSTGAAKKGGRAPISAVCDYAEPMPD 415

Query: 408 RGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDL 467
            GL    TP +D V  T  VA+G  V +F+TG GTP G   VPV+K++T TE+ANR  D+
Sbjct: 416 TGLSLVCTPGNDVVAVTGLVAAGCNVVIFSTGLGTPTGNPIVPVLKISTNTEIANRLKDI 475

Query: 468 MDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQ 507
           +D + G +  G   + +V   LF  +++ AS      SD+
Sbjct: 476 IDFDCGPVIEGTP-LSDVSQALFERVIETASRDYVVKSDR 514


>UniRef50_UPI00017F3110 galactarate dehydratase n=1 Tax=Escherichia coli O157:H7 str.
          EC4024 RepID=UPI00017F3110
          Length = 114

 Score =  158 bits (400), Expect = 4e-37,   Method: Compositional matrix adjust.
 Identities = 75/82 (91%), Positives = 80/82 (97%)

Query: 1  MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDI 60
          MA+IEIRQ +PTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVAL+DI
Sbjct: 1  MADIEIRQASPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALVDI 60

Query: 61 PANGEIIRYGEVIGYAVRAIPR 82
          PA+GEI+RYGEVIGYAVRAI R
Sbjct: 61 PAHGEIVRYGEVIGYAVRAIRR 82


>UniRef50_Q0KC73 D-Galactarate dehydratase n=4 Tax=Burkholderiales
           RepID=Q0KC73_RALEH
          Length = 386

 Score =  154 bits (389), Expect = 8e-36,   Method: Compositional matrix adjust.
 Identities = 116/389 (29%), Positives = 185/389 (47%), Gaps = 30/389 (7%)

Query: 119 TFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYG 178
           TF GY   +G+VG +N + + + +     V   + + +   +      V G  G +  + 
Sbjct: 6   TFLGYPRENGAVGVRNWVAVVSVMDNCNPVTRTIARTVGGCIPVTTLFVRGQFGADLDFA 65

Query: 179 CGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGL---GCEKLQPERLLTGTDDVQAIPV 235
                          ++  +  NPN    V+++GL     E++      TG       PV
Sbjct: 66  -------------FESLAGLGRNPNIAA-VLLVGLEESSTEEVARRIRSTGK------PV 105

Query: 236 ESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFS 295
           E    V LQ +  V   + + +  + A R     ++ +R  CP S LV+G++CGGSD  S
Sbjct: 106 E---CVHLQPDGTV---ACIAEGTRKASRLSLAASKARRVPCPVSSLVIGVECGGSDTTS 159

Query: 296 GVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEME-WYDN 354
           G++ NP +G  +D++V  G TV+ SE +E   A HL   RA +  V +  +  +    D 
Sbjct: 160 GLSCNPVIGRMADMVVAGGGTVIISETSEFIGAEHLFAERAADGRVREAFVTAVRNMEDL 219

Query: 355 YLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAA 414
            ++ G   R   PSP NK+GGL  V EKALG++AK+G S +V VL  G+ P K+GL +  
Sbjct: 220 AISRGVDMREDQPSPDNKRGGLTTVEEKALGAMAKAGTSPLVGVLRYGEAPQKKGLHFMD 279

Query: 415 TPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGT 474
            PA+     T   A G  +  F TG G P G M  P +K+       +   D +D +   
Sbjct: 280 APAAAVENLTALAAGGCQLTFFGTGVGNPIGSMVAPTVKVCGNVNTLHTMADNIDFDVSG 339

Query: 475 IATGEETIEEVGWKLFHFILDVASGKKKT 503
           +    + I ++G +LF + +DVASG + T
Sbjct: 340 VLQNGDKISDLGEQLFGYAMDVASGTRLT 368


>UniRef50_C5EFV8 Hydrolase n=1 Tax=Clostridiales bacterium 1_7_47FAA
           RepID=C5EFV8_9FIRM
          Length = 385

 Score =  151 bits (381), Expect = 6e-35,   Method: Compositional matrix adjust.
 Identities = 111/394 (28%), Positives = 185/394 (46%), Gaps = 39/394 (9%)

Query: 119 TFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYG 178
           TF GY   DG  G +N + I ++      +   V ++I           +G + +   +G
Sbjct: 4   TFMGYARPDGRYGVRNYVAIISTADNSNFIARRVAQMI-----------NGTIPVCPCFG 52

Query: 179 CGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESA 238
            G     P   + I+T+  +  NPN    V+V       L+P           A+  + A
Sbjct: 53  RGEI--GPDMDLHIKTMGGMGANPNVHSAVVV------SLEP-----------ALAEKIA 93

Query: 239 SIVSLQDEKHVGFQ--------SMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGG 290
           +++    +K   F            E  ++ A R + + +  QR       L +G++CGG
Sbjct: 94  AVIRATGKKAETFSMDECGGSIGCTEQAVRAARRLIIEASMEQRVEVGIEHLHLGVECGG 153

Query: 291 SDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEME 350
           SD  SG+ +NPA G  +D LV  G TV+ SE TE   A ++L  RAV  E+G+R+++ + 
Sbjct: 154 SDTTSGLVSNPATGLVADQLVDAGGTVILSETTEWMGAENILLKRAVTPELGERIVKAIR 213

Query: 351 WYDNYL-NMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRG 409
           WY++Y+ ++G      NP+P N KGGL+ + EKALGSI K G   I ++L+  + P + G
Sbjct: 214 WYEDYIKSIGVDLNGFNPAPDNIKGGLSTIEEKALGSIKKGGTRPIQDMLTCSEAPGRPG 273

Query: 410 LIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMD 469
           +     P       T    +G  + +F+TG+G P G    P IK+        +  + +D
Sbjct: 274 MYLMDAPTGGVENTTALAGAGCQLIIFSTGKGNPLGNPIAPTIKVTGNERTIGKSGENID 333

Query: 470 INAGTIATGEETIEEVGWKLFHFILDVASGKKKT 503
           ++   + T +  I+  G  L+  ++D A GK  T
Sbjct: 334 VDLSAVITEDMDIQAAGNILYEKMIDHADGKLTT 367


>UniRef50_Q13SA4 Altronate dehydratase n=48 Tax=Bacteria RepID=Q13SA4_BURXL
          Length = 450

 Score =  143 bits (360), Expect = 2e-32,   Method: Compositional matrix adjust.
 Identities = 131/431 (30%), Positives = 197/431 (45%), Gaps = 47/431 (10%)

Query: 101 TLPLATKVPEPLPPLEGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDL 160
           T+   T V  P    +  T +GY   DG  G +N++ +   V C   V   +V      L
Sbjct: 10  TIMTDTSVASPSAASQQPTLQGYLRRDGRKGIRNVVAVAYLVECAHHVAREIVTQFREPL 69

Query: 161 -------LPKYPNVDGVVGLNHLYGC-GVAINAPAAVVPIRTIHNISLNPNFGGEVMVIG 212
                    + P V       HL G  G   N+ A     + +  ++ +PN G  V+ + 
Sbjct: 70  DAFDDPSAEREPPV-------HLIGFPGCYPNSYAE----KMLERLTTHPNVGA-VLFVS 117

Query: 213 LGCEKLQPERLLTGTDDVQAI--PVESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLN 270
           LGCE +    L+   D V+A   PVE   ++++Q++   G +S ++  +       ++L 
Sbjct: 118 LGCESMNKHYLV---DVVRASGRPVE---VLTIQEKG--GTRSTIQYGVDWIRSARKQLA 169

Query: 271 QRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIH 330
            +Q+     SELV+G  CGGSD  SG+TANPAVG A D L+  GAT +F E  E+     
Sbjct: 170 AQQKVPMALSELVIGTICGGSDGTSGITANPAVGRAFDHLIDAGATCIFEETGELVGCEF 229

Query: 331 LLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKS 390
            +  RA   E+G+ ++  +     Y ++      A    GN  GGL    EK+LG+ AKS
Sbjct: 230 HMKTRAARPELGEEIVACVAKAARYYSILGHGSFAV---GNADGGLTTQEEKSLGAYAKS 286

Query: 391 GKSAIVEVLSPGQRPTKRGLI-----------YAATPASDFVCGTQQVASGITVQVFTTG 439
           G S IV ++ PG  P   GL            +     SD     + +A G  V +FTTG
Sbjct: 287 GASPIVGIVKPGDIPPTGGLYLLDVVPDGEPRFGFPNISDNAEIGELIACGAHVILFTTG 346

Query: 440 RGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASG 499
           RG+  G    PVIK+             MD++AG I  G  T++EVG ++F   + V+ G
Sbjct: 347 RGSVVGSAISPVIKVCANPATYRNLAGDMDVDAGRILEGRGTLDEVGREVFEQTVAVSRG 406

Query: 500 ---KKKTFSDQ 507
              K +T   Q
Sbjct: 407 AASKSETLGHQ 417


>UniRef50_B5IW17 D-galactarate dehydratase / Altronate hydrolase, C terminal domain
           superfamily n=1 Tax=Thermococcus barophilus MP
           RepID=B5IW17_9EURY
          Length = 394

 Score =  142 bits (358), Expect = 3e-32,   Method: Compositional matrix adjust.
 Identities = 111/390 (28%), Positives = 188/390 (48%), Gaps = 31/390 (7%)

Query: 120 FEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGC 179
            +G+R  +G  G +N + + +SV C        ++I  R         +G  G+   +G 
Sbjct: 6   IKGWRRENGDFGIRNHIVVLSSVACAN---HAALEIARRTGAIPIIQEEGACGM---FG- 58

Query: 180 GVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESAS 239
                       +R + N+  +PN     +V+GLGCE +   +L    D++      + S
Sbjct: 59  ------EDRKRFLRCMANVGSHPNVAW-TLVVGLGCEGIDAHQL---ADEISKRGRNAES 108

Query: 240 IVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTA 299
           ++     + +G    VE  +++  R  + L  R RET    ELV+G++CG SD  SG+ +
Sbjct: 109 LLI----QELGMDKTVEKGIELVNRAKENLTPR-RETAGVEELVIGLKCGASDYTSGLIS 163

Query: 300 NPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMG 359
           NP+VG A D+L+  G T + +E  E+  A  +L  RA ++EV +  L  ++     +N  
Sbjct: 164 NPSVGKAVDILIEYGGTAIITERLELVGAEQILARRAKSKEVAEDFLRRIKKAVEDVNKR 223

Query: 360 KTDR-SANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPAS 418
             D   + PS GN KGGL  + EK+LG++ K+G + +   L  G++P  RGL +   P  
Sbjct: 224 GVDWIGSQPSMGNIKGGLTTIEEKSLGAVKKAGNAQLEGCLDYGEKPKGRGLYFMDGPGY 283

Query: 419 DFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTI--- 475
           D    +  + +G  + +FTTG GT  G    PVIK+      A +  D +D++   +   
Sbjct: 284 DVKAVSGLMCAGSHIILFTTGLGTYLGSPVSPVIKITGNPTTARKLRDAIDVDLSILLEE 343

Query: 476 -----ATGEETIEEVGWKLFHFILDVASGK 500
                A+ +E +E  G  +   I+ VA+GK
Sbjct: 344 IISRDASLDEILEIGGRMILEEIVRVANGK 373


>UniRef50_A8RT57 Putative uncharacterized protein n=1 Tax=Clostridium bolteae ATCC
           BAA-613 RepID=A8RT57_9CLOT
          Length = 412

 Score =  138 bits (348), Expect = 5e-31,   Method: Compositional matrix adjust.
 Identities = 119/397 (29%), Positives = 189/397 (47%), Gaps = 40/397 (10%)

Query: 118 YTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLY 177
           Y++ GY   +G++G +N + +  +V C + V   +V+      L   P  + VVG +   
Sbjct: 14  YSWMGYVRKNGAMGIRNKVLVIYTVECASFVAREIVR------LAGDPETE-VVGFS--- 63

Query: 178 GCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVES 237
             G   N  A    +R +  +  +PN G  V+ +GLGCE +QPE L     D+     + 
Sbjct: 64  --GCTDNEYA----VRLLIALIRHPNVGA-VLTVGLGCEYVQPEWLA----DIAGKEGKE 112

Query: 238 ASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGV 297
           A+ + +Q E   G +  +E  L +     ++L   +R+     +L++G +CGGSD  SG+
Sbjct: 113 AAWMFIQQEG--GTRKTIEKGLAVVGLMRERLKDTKRKPMGIRDLIIGAECGGSDYTSGL 170

Query: 298 TANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEM-EWYDNYL 356
             N  VG   D L   G T +F E+ E      +L  RA NE    R  +E+ + YD  L
Sbjct: 171 AGNVVVGRFFDRLTDLGGTAIFEEIVEAIGLKEMLVGRAANE----RARQEIGDTYDKAL 226

Query: 357 NMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGL-IYAAT 415
              K+ R  + SPGN  GGL+ + EK++G++ KSG   I  VL  G +P   GL +  +T
Sbjct: 227 EYCKSVRQYSVSPGNFAGGLSTIEEKSMGALIKSGSRPIEGVLKVGVKPPHPGLWLLDST 286

Query: 416 PASDFVC----------GTQQVASGITVQVF-TTGRGTPYGLMAVPVIKMATRTELANRW 464
           P   ++           G   +A+  +  VF  TGRG   G   VP IK+   +      
Sbjct: 287 PDPYWMQFGITNPNDSEGLMDLAACHSHIVFLVTGRGNVVGSAVVPCIKITGNSATYRAM 346

Query: 465 FDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKK 501
            + MD +AG +  G  + +E+  +L     +VASG K
Sbjct: 347 EEDMDFDAGPVLEGRCSQDEMAQRLLKMAAEVASGTK 383


>UniRef50_B1M8U1 Altronate dehydratase n=55 Tax=root RepID=B1M8U1_METRJ
          Length = 426

 Score =  136 bits (343), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 117/390 (30%), Positives = 178/390 (45%), Gaps = 34/390 (8%)

Query: 119 TFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYG 178
           TF G+R  +G VG +N + +           + V             NV G + L H YG
Sbjct: 42  TFMGWRRENGRVGVRNHVVLLPLDDLSNAACEAVAN-----------NVKGTMALPHAYG 90

Query: 179 ---CGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPV 235
               G  ++     +  RT+  I  NPN    V+VIG+  E     R+      V+ I  
Sbjct: 91  RLQFGEDLD-----LHFRTLIGIGSNPNVAA-VVVIGI--EDQWTNRV------VEGIAR 136

Query: 236 ESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFS 295
               +V    E H G  ++V      A+R +Q   + QRE CP ++L V  +CG SD  +
Sbjct: 137 TGKPVVGFGIEGH-GDIAIVAKASYQAKRFVQWATELQREECPIADLWVSTKCGESDTTT 195

Query: 296 GVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWY-DN 354
           G+ + P VG   D L+  G   +F E +E+  A HL   RA++ EV  +     + Y D+
Sbjct: 196 GLASCPTVGNMYDKLIPHGIYGVFGETSEITGAEHLCRERAISPEVSDKWYAMWKAYQDD 255

Query: 355 YLNMGKTD--RSANPSPGNKKGGLANVVEKALGSIAKSGKSA-IVEVLSPGQRPTKR-GL 410
            +   KTD    + P+ GN  GGL  + EKALG++ K G     ++ L P + PTK  GL
Sbjct: 256 VIEAHKTDDLSDSQPTKGNIAGGLTTIEEKALGNLEKIGHECRFIDALQPAEAPTKGPGL 315

Query: 411 IYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDI 470
            +  T ++   C T   A+G  V  F TG+G   G   VPVIK+           + +D+
Sbjct: 316 YFMDTSSAAAECVTLMAAAGYVVHTFPTGQGNVIGNPIVPVIKITGNPRTVRTMGEHIDV 375

Query: 471 NAGTIATGEETIEEVGWKLFHFILDVASGK 500
           +   + T E TI + G  L   ++  A+G+
Sbjct: 376 DVSGVLTREMTIPQAGDALIDMVVRTANGR 405


>UniRef50_A9V9F3 Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9V9F3_MONBE
          Length = 958

 Score =  136 bits (342), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 118/416 (28%), Positives = 182/416 (43%), Gaps = 19/416 (4%)

Query: 96  APPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVGTKN---LLGITTSVHCVAGVVD-- 150
           APP      A   P PL    G+   G R A    GT+N   +LGI++     A  ++  
Sbjct: 114 APPTKRDESAAATPAPLTTFMGFPRGGNRGA----GTRNYVVILGISSRAAGFARALERQ 169

Query: 151 YVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAI----NAPAAVVPIRTIHNISLNPNFGG 206
           +   + +   L      DGVV + H  G   A     N       +R +   +++PN G 
Sbjct: 170 FTHTLEQARTLQGQATCDGVVAVAHTEGGLDAKLTTDNENNVEKVLRVLAGFAVHPNVGA 229

Query: 207 EVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQIAERHL 266
            V+ +  G E +    +L         P++     +L  +     ++M +    + E +L
Sbjct: 230 -VLFLDHGDEVVTTRHVLEYIR-AHDYPLDDVPYRALSLKNQTMKEAMHQATELVEELYL 287

Query: 267 QKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVR 326
           Q   Q QR       L    QCGGSDAFSG++ANP  G+ +  LV  G + + +E  E+ 
Sbjct: 288 QA-QQHQRVAVGVEHLCFAQQCGGSDAFSGISANPLAGWMARELVAQGGSAVLAETDELI 346

Query: 327 DAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGS 386
            A   +  R  + +     L+ ++ Y  Y N        NPS GN   GL N+  K+ G+
Sbjct: 347 GAESYVLQRVRDYDTADHFLQLVDRYYRYTNRRGHSPEGNPSGGNLYRGLYNITLKSAGA 406

Query: 387 IAKSGKSAIVE-VLSPGQR--PTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTP 443
             K      ++ VL  GQR  P   G  +  +P +D      QVA+G  + VFTTG G+ 
Sbjct: 407 AMKKLPDVRLDHVLEYGQRLQPEGHGYAFMDSPGNDLESIAGQVAAGCNMIVFTTGNGSV 466

Query: 444 YGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASG 499
                VP IK+ T T+      D MD+NAG    GE ++ ++G + +   +  ASG
Sbjct: 467 TNFPFVPTIKVLTTTKRYQLLSDDMDVNAGRFLDGEVSLSQLGREAYQLFVRAASG 522


>UniRef50_Q1AYL8 D-galactarate dehydratase/Altronate hydrolase-like protein n=2
           Tax=Bacteria RepID=Q1AYL8_RUBXD
          Length = 895

 Score =  135 bits (340), Expect = 4e-30,   Method: Compositional matrix adjust.
 Identities = 146/533 (27%), Positives = 229/533 (42%), Gaps = 58/533 (10%)

Query: 22  DNVAIIVNDNGLKAGTRFPDG---LELIEHIPQGHKVALLDIPANGEIIRYGEVIGYAVR 78
           DNVAI      L+AGTR   G     L   + +GH+ A+  I     ++ +G   G+A+R
Sbjct: 19  DNVAIATRR--LEAGTRVRCGGSSFSLSHAVLEGHRFAVSRIGEGEALLSWGLPFGWALR 76

Query: 79  AIPRGSWIDESMVV-----------LPEAPPLHTLPL------------ATKVPEPLPPL 115
            I  G ++  + ++           LP  P     PL              +VP    P 
Sbjct: 77  EIRPGEYVCNARILRVLRERRVDLDLPGEPNFRDDPLRPYVLDERNFGPGEQVPRHERP- 135

Query: 116 EGYTFEGY-RNADGSVGTKN---LLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVV 171
              TF GY R A    GT+N   +LG+T+     A  ++  +      L    P +DG+V
Sbjct: 136 --GTFMGYGRGAARGAGTRNHIVVLGLTSRTGPYARALERRLA----GLAAGVPGLDGIV 189

Query: 172 GLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVI-GLGCEKLQPERLLTGTDDV 230
            + H  G G         + +RT+    ++PN G  + V  G G         LTG   +
Sbjct: 190 AVAHTEG-GEDRPPNNLGLLLRTLAGFMVHPNAGAVLAVDDGRGA--------LTG-GAL 239

Query: 231 QAIPVESASIVSLQDEKHVGFQSMVEDILQIAERH----LQKLNQRQRETCPASELVVGM 286
           +    E    +     + +  +      L+  ER     L +    +R   P S L + +
Sbjct: 240 RRYMKERGYPLREVPHRFMTLRGSFAGELRRGERAVRGWLGEAGSARRSPQPLSRLRLAL 299

Query: 287 QCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLL 346
           QCGGSDAFSGV+ANP V + +  L+R G +   +E  E+  A   +     +    +R L
Sbjct: 300 QCGGSDAFSGVSANPLVAWVARELLRHGGSANLAETDELIGAERYVLENVRDLATARRFL 359

Query: 347 EEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSP-GQRP 405
           + +E +   +         NPS GN   GL N+  K++G+  K      ++ + P   R 
Sbjct: 360 QTVERFRELVGRHGHTAEGNPSGGNNYRGLYNIAIKSIGAARKKDPGVRLDYVIPYAGRM 419

Query: 406 TKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWF 465
              G  +  +P +D      QVASG  V  FTTG G+      VP IK+ + T       
Sbjct: 420 DAPGYYFMDSPGNDLESVAGQVASGANVIFFTTGNGSITNFPFVPTIKVVSTTGRYRLLA 479

Query: 466 DLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFN 518
           D MD+NAG    G   +EE+G   F   + VASG ++T  ++ G H+Q++++ 
Sbjct: 480 DEMDVNAGAYLDG-TPMEELGRDAFDLAVRVASG-ERTAGERAG-HSQVSIWR 529


>UniRef50_C5EF38 Altronate dehydratase n=2 Tax=Clostridiales RepID=C5EF38_9FIRM
          Length = 405

 Score =  127 bits (318), Expect = 1e-27,   Method: Compositional matrix adjust.
 Identities = 115/394 (29%), Positives = 176/394 (44%), Gaps = 38/394 (9%)

Query: 118 YTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLY 177
           ++++GY    G+ G +N + +  +V C   V     +I+E      +P+V+ +VG +   
Sbjct: 4   WSWQGYGRKHGAPGIRNRVLVIYTVKCSEFVAR---RIVEES---GHPDVE-LVGFD--- 53

Query: 178 GCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVES 237
             G   N  A  + I  I +    PN G  V+ +GLGCE +QP+ L     DV     + 
Sbjct: 54  --GCTDNQYAVDLLISLIKH----PNVGA-VLTVGLGCEYIQPQWLA----DVAVKEGKE 102

Query: 238 ASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGV 297
           AS +S+Q E   G +  V          L++L    R      +LV+G +CGGSD  SG+
Sbjct: 103 ASWMSIQQEG--GTKPTVTKGTAWVRETLERLKHTPRVRMGFKDLVIGAECGGSDYTSGL 160

Query: 298 TANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLN 357
             N  VG   D LV  G   +F E+ E      LL  RA + E  + L      YD  L+
Sbjct: 161 AGNVVVGRFFDRLVDLGGCAIFEEIVEAIGLDGLLVGRAADPEAARELRYT---YDKALD 217

Query: 358 MGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGL-IYAATP 416
             ++ R  + SPGN  GGL+ + EK++G++ KSG   I  VL     P   GL +  +TP
Sbjct: 218 YCRSVRQYSVSPGNFAGGLSTIEEKSMGAVIKSGSRPIEGVLKVSVPPKHGGLWLLDSTP 277

Query: 417 ASDFVCG-----------TQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWF 465
              F+                ++ G  +    TGRG   G    P IK+    E  +R  
Sbjct: 278 DPHFMQFGITNPNDNEGLMDLISCGAHIVFLVTGRGNVVGSAVAPCIKITGNHETFSRME 337

Query: 466 DLMDINAGTIATGEETIEEVGWKLFHFILDVASG 499
           + MD +A  I  G  + +E+   L  ++   A G
Sbjct: 338 EDMDFDASPILYGGMSQKEMALDLAAYVAGTAGG 371


>UniRef50_D0Z3R7 Altronate hydrolase n=2 Tax=Bacteria RepID=D0Z3R7_LISDA
          Length = 391

 Score =  124 bits (311), Expect = 1e-26,   Method: Compositional matrix adjust.
 Identities = 120/393 (30%), Positives = 185/393 (47%), Gaps = 48/393 (12%)

Query: 119 TFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYG 178
           TF+G+   +G+ G +N + I     C  G+   + K I+          D VV  NH Y 
Sbjct: 4   TFKGFPRPNGTFGIRNNVMIVAIDECCEGIARNISKEID----------DSVVVTNH-YT 52

Query: 179 CGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESA 238
           C    N       I TI + + NPN  G V+VI +GC  + PE ++      + +PV + 
Sbjct: 53  CMYGGNEEM----IDTIIHTATNPNIAG-VLVIAMGCGSIDPE-MVAEPIRKEGLPVHTL 106

Query: 239 SIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVT 298
           +++     K+ G    ++D L +A+      +  +R   P S L +G++CGGSD  SG+ 
Sbjct: 107 TVI-----KNKGTIETIKDGLVLAKELKAYADSVERIDAPISALRIGIKCGGSDTSSGLA 161

Query: 299 ANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVG---KRLLEE--MEWYD 353
           +NP+VG ASD LV  GAT M  E+ E+     +L  R+V  EVG   +RL+ E    W+ 
Sbjct: 162 SNPSVGAASDKLVDMGATTMAGELLELLGCEEILKARSVTPEVGSKIERLIAEDLKRWH- 220

Query: 354 NYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPG----QRPTKRG 409
                   + +   S GN  GGL  + EK+ G++ K+G   I + L       ++PTK G
Sbjct: 221 ------VIEGTETMSIGNSVGGLTTIDEKSQGAMHKTGTQPIQDCLRINHIHREKPTKPG 274

Query: 410 LIYAATPASDFVCG--TQQVAS-GITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFD 466
                T     +CG      AS G  + ++T G    +    VPVI+++  + L      
Sbjct: 275 FYLTETT---MLCGGAAMHFASLGCQLILWTAG-AAGFNNSIVPVIRVSGNSALITAD-- 328

Query: 467 LMDINAGTIATGEETIEEVGWKLFHFILDVASG 499
            MDINA  I    +TI+ V  K+   +  VA G
Sbjct: 329 -MDINACGIMDATDTIDNVSNKIIDKVFAVADG 360


>UniRef50_C2DK38 Putative uncharacterized protein n=2 Tax=Escherichia
           RepID=C2DK38_ECOLX
          Length = 65

 Score =  123 bits (308), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 58/64 (90%), Positives = 61/64 (95%)

Query: 286 MQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRL 345
           M CGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVT+V DAIHLLTPRA+NEEVG+ L
Sbjct: 1   MHCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTDVHDAIHLLTPRAINEEVGRCL 60

Query: 346 LEEM 349
           LEEM
Sbjct: 61  LEEM 64


>UniRef50_A8H9C8 D-galactarate dehydratase/Altronate hydrolase domain protein n=3
           Tax=Proteobacteria RepID=A8H9C8_SHEPA
          Length = 393

 Score =  121 bits (304), Expect = 5e-26,   Method: Compositional matrix adjust.
 Identities = 115/402 (28%), Positives = 185/402 (46%), Gaps = 51/402 (12%)

Query: 119 TFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNH--- 175
           +F G+   DGSVG +N + I     C  G+   +   I+          +G+V  N+   
Sbjct: 4   SFIGFGRTDGSVGIRNHVLIMAVDECCDGIARAIADSID----------NGIVVTNYNTC 53

Query: 176 LYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPV 235
           +YG    +        I T+ +   NPN  G V+V+ +GC  + PE        + A P+
Sbjct: 54  MYGGNEEM--------INTMIHTGNNPNVAG-VLVLAMGCGSIDPE--------IVAAPI 96

Query: 236 ESAS--IVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDA 293
                   SL   K  G ++ +    ++A++  Q      R   P SEL++G++CGGSD 
Sbjct: 97  RETGRPAFSLVCMKQQGTRATINQGKELAQQLQQAAQDAPRVEKPISELIIGVKCGGSDT 156

Query: 294 FSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRL-----LEE 348
            SG+ +NP+VG A D LV  GAT +  E+ E+     +L  RAV+ EV  +L      EE
Sbjct: 157 SSGIASNPSVGRAVDTLVDMGATAIAGELIELVGCESILRQRAVSTEVADKLERLIHQEE 216

Query: 349 MEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPG----QR 404
             W+ +   +         S GN  GGL  + EK+ G+++K+G  AI +VL       ++
Sbjct: 217 ARWHVDGAEV------ETMSIGNSVGGLTTLEEKSFGALSKTGTRAIQDVLQINHLVHEK 270

Query: 405 PTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRW 464
           PT  G   +         G    A G  + ++TTG G  +    VPVI+++    L N  
Sbjct: 271 PTTAGFYLSEATHLCGSAGMHFAALGAHLILWTTG-GAGFNNPIVPVIRVSGNQYLLN-- 327

Query: 465 FDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSD 506
            + +DI+A  I   EE +E V  ++   +  VA G++    +
Sbjct: 328 -EDIDIDASGIMRAEEGVESVAERIVAKVSKVAQGQQTNIEE 368


>UniRef50_B6WWW3 Putative uncharacterized protein n=2 Tax=Desulfovibrio
           RepID=B6WWW3_9DELT
          Length = 399

 Score =  115 bits (288), Expect = 4e-24,   Method: Compositional matrix adjust.
 Identities = 99/321 (30%), Positives = 156/321 (48%), Gaps = 19/321 (5%)

Query: 193 RTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQ 252
           R I  ++ NPN GG V+++G   +    E   T  + V+ I      + +L   +  G  
Sbjct: 63  RVITGLAKNPNVGG-VLLVGNKPDGGYAE--FTYENIVENIMASGKPVETLFISRDGGHA 119

Query: 253 SMVEDILQIAERHLQKL-NQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLV 311
           + +   +Q A RHL +L + ++RE     +L + ++CG SDA SG+  NP +GY  D L 
Sbjct: 120 ACIGLGIQKA-RHLAELCSAQRREEVDWGKLCIAVKCGYSDATSGMAGNPVIGYVFDRLC 178

Query: 312 RCGATVMFSEVTEVRDAIHLLTPR---AVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPS 368
             G T +FSE TEV  A  ++  R   A   +V    + ++E  +     G+  RS NP 
Sbjct: 179 DAGGTAIFSETTEVIGAEEIVARRFADAGQRDVFLSCVRKVE--EEAKATGQDIRSINPI 236

Query: 369 PGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVA 428
           P N + GL  + EK+LG+IAK+G   I++ +  G+ P+  GL Y  +  S         +
Sbjct: 237 PANIEAGLTTLEEKSLGAIAKAGTKPIMQCVRYGESPSAPGLNYMDSWMSSSALFAGFSS 296

Query: 429 SGITVQVFTTGRGTPYGLMAVPV--------IKMATRTELANRWFDL-MDINAGTIATGE 479
           +G  + +F  G G       +PV        I  AT    A     L +D N+G + + +
Sbjct: 297 AGAVLNIFQFGGGAMPDKCMMPVADTGVVAPILFATGNPRAYDHGKLEIDFNSGVVISEK 356

Query: 480 ETIEEVGWKLFHFILDVASGK 500
            +IEE G KL   I D+ASG+
Sbjct: 357 ASIEETGEKLIRHICDIASGR 377


>UniRef50_D2PZR0 D-galactarate dehydratase/Altronate hydrolase domain protein n=1
           Tax=Kribbella flavida DSM 17836 RepID=D2PZR0_9ACTO
          Length = 923

 Score =  112 bits (281), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 108/411 (26%), Positives = 182/411 (44%), Gaps = 34/411 (8%)

Query: 119 TFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYG 178
           TF GY  A G  GT+N + +  +    +G   +V ++  R         DGVV + H  G
Sbjct: 148 TFLGYPRAQGPAGTRNHVVLLATSSRSSG---FVTELARR--FDGAAAGDGVVPVAHTEG 202

Query: 179 CGVAINAPAAVVPIRTIHNISLNPNFGG-------EVMVIGLGCEKLQPERLLTGTDDVQ 231
                     ++ + T+   +LNPN G        E +V G        ER   G  ++Q
Sbjct: 203 AEQGTPNNLTLL-LATLAGFALNPNVGAVLVVDTEEDLVSGQAIRDFMAER---GYPELQ 258

Query: 232 AIPVESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGS 291
              V  A        +  GF+  +     + E  L  ++ +QR   P ++L + +QCGGS
Sbjct: 259 ---VPHAFFT-----RQAGFEQDLTAAGALIEPWLPVVDAQQRTEVPLADLWIALQCGGS 310

Query: 292 DAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEW 351
           DAFSGVTANP  G  +  ++R G T + +E  E+  A   +     +    +R L  ++ 
Sbjct: 311 DAFSGVTANPLSGAVAREVIRHGGTAVLAETDELIGAEGYVLKNVRDLPTARRFLRTVQA 370

Query: 352 YDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSA----IVEVLSPGQRPTK 407
           +   +         NPS GN   GL N+V K++G+  K  +      +++   P   P  
Sbjct: 371 FKERVGWHGHTAEGNPSGGNVYRGLYNIVLKSVGAARKLDRDVRLDHVIDYAEPVPGP-- 428

Query: 408 RGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDL 467
            G ++  +P +D      +VASG  +  FTTG G+      VP IK  T +   +     
Sbjct: 429 -GFVFMDSPGNDLESIAGEVASGCNLIFFTTGNGSITNFPFVPTIKFVTTSARYDLLEAE 487

Query: 468 MDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFN 518
           MD++AG   TG  +++ +  +     + VASG+    + +   H+Q++++ 
Sbjct: 488 MDVDAGRYLTG-TSMDALTAETLDLTVRVASGEPS--AGERAGHSQVSIWR 535


>UniRef50_A7VSH2 Putative uncharacterized protein n=1 Tax=Clostridium leptum DSM 753
           RepID=A7VSH2_9CLOT
          Length = 404

 Score =  112 bits (279), Expect = 4e-23,   Method: Compositional matrix adjust.
 Identities = 116/414 (28%), Positives = 173/414 (41%), Gaps = 46/414 (11%)

Query: 121 EGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCG 180
           +GY  ADGS G +N + +  +V C   + +     I R       +V+ V       G  
Sbjct: 8   QGYVRADGSKGIRNKVLVIYTVECCRALSER----IARHFQELGQDVEAV-------GTS 56

Query: 181 VAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLL-----TGTDDVQAIPV 235
             ++  A    IR +   S +PN G  V+ IG GCE  +P+++       G +       
Sbjct: 57  SCLDNQA---DIRRLLRFSTHPNVGA-VLAIGHGCEYTKPQKIAEFARQRGRESQWFYQQ 112

Query: 236 ESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFS 295
           E+   V   D+            L+I    L+KL    RE    SELV+  +CGGSD  S
Sbjct: 113 EAGGSVKGYDKG-----------LEIVRELLKKLEATPREPMYLSELVLAGECGGSDFTS 161

Query: 296 GVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNY 355
           G+  N  +G   D LV  G T +F E+ E       L  RA    V   +      YD  
Sbjct: 162 GLAGNALIGRVFDRLVDAGGTAIFEELCEGLGLKEYLAARAATPRVADDI---RRAYDKT 218

Query: 356 LNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGL-IYAA 414
           +         + +PGN  GGL  + EK++G++ KSG   I  VL   Q P K GL +   
Sbjct: 219 MEFCVKYGHFSIAPGNMDGGLTTIEEKSMGAMVKSGTRPIRGVLKIAQAPKKPGLYLLDT 278

Query: 415 TP----------ASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRW 464
           TP          A+D       +A G  +    TGRG   G    PVIK+        R 
Sbjct: 279 TPDEKLEPAHHEAADPSDMLDLIACGAHIVFLVTGRGHVVGTPVSPVIKVTGNPRTYGRM 338

Query: 465 FDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFN 518
            D +D  A    TG+ +++++   L   +  VA G ++T +++ G    +  FN
Sbjct: 339 KDDIDFCAAPALTGDRSLDDLSDDLLELVSRVAQG-ERTNAERLGHREGILYFN 391


>UniRef50_B5JYR2 D-Galactarate dehydratase n=1 Tax=Octadecabacter antarcticus 238
           RepID=B5JYR2_9RHOB
          Length = 359

 Score =  111 bits (278), Expect = 5e-23,   Method: Compositional matrix adjust.
 Identities = 81/307 (26%), Positives = 136/307 (44%), Gaps = 10/307 (3%)

Query: 195 IHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSM 254
           I+ I  +PN G  ++V   G    Q  R           P+    IV+L  ++  G Q+ 
Sbjct: 41  INAIIAHPNVGAALVVTHDGASADQLRRFCAELGK----PI---VIVALMAQQ--GMQAA 91

Query: 255 VEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCG 314
            E +       L +  ++ +      +L V ++CGGSDA S + ANPA+G   D L+  G
Sbjct: 92  CETMAAHLRSLLAEAAEQSKSKFLLPDLTVALECGGSDATSALCANPAIGRFVDRLIDAG 151

Query: 315 ATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTD-RSANPSPGNKK 373
            T + SE  E      ++  ++   +V   +L  +   D  +    TD R  NP+  N +
Sbjct: 152 GTAIVSETAEFLGGEDIVLAQSRTPQVADAILAYLSAEDAIMTSDGTDYRGVNPTQENIE 211

Query: 374 GGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITV 433
            GL+ + EK +G++ K G S     L+ G+ PT +GL +  TP       T  V  G  V
Sbjct: 212 AGLSTLTEKTMGALCKIGTSRFAGALNFGEEPTGKGLFFMNTPFFSPTSLTGMVLGGAQV 271

Query: 434 QVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFI 493
            +F  G   P GL   P IK+    +  + W D +D++   + +G          +   +
Sbjct: 272 SLFAMGVFNPSGLPLAPTIKICGNPKTLSDWPDAIDLDVSGVISGRMNYGAAADDILRIV 331

Query: 494 LDVASGK 500
            D+++G+
Sbjct: 332 RDISNGQ 338


>UniRef50_B9MJB7 SMP-30/Gluconolaconase/LRE domain protein n=1 Tax=Diaphorobacter
          sp. TPSY RepID=B9MJB7_DIAST
          Length = 197

 Score = 73.2 bits (178), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 36/66 (54%), Positives = 44/66 (66%)

Query: 18 VHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRYGEVIGYAV 77
          +H  DNVAI+ ND GL AGTR   G  L++ +PQ HKVAL DIP  G + RY  VIGYA+
Sbjct: 1  MHPADNVAIVANDGGLPAGTRLAGGQVLVDKVPQAHKVALEDIPEGGAVRRYNVVIGYAL 60

Query: 78 RAIPRG 83
          + I  G
Sbjct: 61 KFIAAG 66


>UniRef50_B7DPM4 Altronate dehydratase n=1 Tax=Alicyclobacillus acidocaldarius LAA1
           RepID=B7DPM4_9BACL
          Length = 223

 Score = 57.4 bits (137), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 42/143 (29%), Positives = 62/143 (43%), Gaps = 26/143 (18%)

Query: 49  IPQGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWI------------DESMVVLPEA 96
           + +GHK+A   +     + +YG  IG A + I  G W+            D+S V LP  
Sbjct: 40  VSRGHKLADRHVQCGEPVRKYGFPIGLAGQDIEPGEWVHTHNLRTALMERDDSYVYLPSG 99

Query: 97  PPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKII 156
            P+  L             +G TF GY  +DG VG +N + I  +V CV  V + +  + 
Sbjct: 100 SPMPVLD------------DGLTFLGYVRSDGQVGVRNEIWILNTVGCVNKVAERLAAMA 147

Query: 157 ERDLLPKYPNVDGVVGLNHLYGC 179
             D   +   +DGV    H YGC
Sbjct: 148 --DARWRGGGIDGVYHFAHPYGC 168


>UniRef50_C5EF39 Altronate hydrolase n=3 Tax=Clostridiales RepID=C5EF39_9FIRM
          Length = 112

 Score = 56.2 bits (134), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 34/77 (44%), Positives = 43/77 (55%), Gaps = 3/77 (3%)

Query: 13 AFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIE---HIPQGHKVALLDIPANGEIIRY 69
          AF I + D    A+     G +AG     G E I+    IP GHK+AL DI A G I++Y
Sbjct: 7  AFQIDLGDNVATALAGIKAGQEAGLTGDHGEESIKAATDIPAGHKIALKDIGAGGHIVKY 66

Query: 70 GEVIGYAVRAIPRGSWI 86
          G VIG A   IP+GSW+
Sbjct: 67 GVVIGRATADIPKGSWV 83


>UniRef50_D2S1L8 Altronate dehydratase-like protein n=1 Tax=Haloterrigena turkmenica
           DSM 5511 RepID=D2S1L8_9EURY
          Length = 373

 Score = 54.7 bits (130), Expect = 8e-06,   Method: Compositional matrix adjust.
 Identities = 90/357 (25%), Positives = 140/357 (39%), Gaps = 38/357 (10%)

Query: 120 FEGY-RNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYG 178
           F  Y R+ DG VG +N + +  SV C   V D +              V G V   H +G
Sbjct: 13  FTAYDRDRDG-VGVRNRVLVVPSVICSHTVADRIAS-----------EVPGAVSTPHDHG 60

Query: 179 CGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESA 238
           CG   +        RT+  ++ NPN  G  + +GLGCE +Q +RL     D + +PVE  
Sbjct: 61  CGQLGDDSERTE--RTLVGVAANPNVAG-ALAVGLGCETVQSDRLAGSIAD-RGVPVEEV 116

Query: 239 SIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVT 298
           +I     ++  G  +  E  +  A   L+   +  R         +G+        S  T
Sbjct: 117 AI-----QRAGGTDACREAGIDRAT-ALRARTEATRSQVGLEAATIGVVSSDCRPSSLET 170

Query: 299 ANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNM 358
           A+P VG     +V  G   + +    V        P AV E V     E  E +D     
Sbjct: 171 ADPLVGSVVGRIVDAGGRALIAGNERVH-----AHPDAVRERVAT--AEARERFD----- 218

Query: 359 GKTDRSANPSPGNKKGGLANVVEKALGSIAKS-GKSAIVEVLSPGQRPT-KRGLIYAATP 416
           G TDR+ + SP           +     + +  G  ++ +VL  G+R T   G+     P
Sbjct: 219 GVTDRAYD-SPAAVTATRKRAADATPEQVRRLWGDRSVRDVLEYGERATHDAGVALVDAP 277

Query: 417 ASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAG 473
           ++     T   A+G  + +  T  G P G   VPV+ +    +  +   D +D  AG
Sbjct: 278 SAFDEAATALAAAGAQIVIHVTADGIPAGHPIVPVLAVTGDRDTYDALCDDLDTFAG 334


>UniRef50_Q0RXU4 Possible sulfolactate sulfo-lyase small subunit n=1
          Tax=Rhodococcus jostii RHA1 RepID=Q0RXU4_RHOSR
          Length = 102

 Score = 50.8 bits (120), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 33/89 (37%), Positives = 49/89 (55%), Gaps = 10/89 (11%)

Query: 6  IRQETPTAFYIKVHDTDNVAIIVNDNGLKAGT------RFPDG--LELIEHIPQGHKVAL 57
          ++  T    ++  HD D VA+ V D  L+ G       R P+   LEL++ IP GHKVAL
Sbjct: 1  MKNATRAPDFLAHHDGDVVAVAVRD--LEPGAAEGGYLRGPESVSLELLDPIPLGHKVAL 58

Query: 58 LDIPANGEIIRYGEVIGYAVRAIPRGSWI 86
          +D+ A  ++I YG  +G     I RGS++
Sbjct: 59 VDLEAGQDVIEYGLRVGVTTEKITRGSYV 87


>UniRef50_C5EFR7 Predicted protein n=1 Tax=Clostridiales bacterium 1_7_47FAA
          RepID=C5EFR7_9FIRM
          Length = 93

 Score = 49.7 bits (117), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 26/73 (35%), Positives = 43/73 (58%), Gaps = 3/73 (4%)

Query: 16 IKVHDTDNVAIIVND--NGLKAGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRYGEVI 73
          I+  + DNVA+++ D   GL  G    D + + + IP GHK+AL DI A  ++ +YGE +
Sbjct: 9  IRFTEKDNVAVVLEDVKPGLVMGLDGAD-ITVGDEIPYGHKIALSDIAAGEKVYKYGEPV 67

Query: 74 GYAVRAIPRGSWI 86
             ++ I +G W+
Sbjct: 68 ARCIKDIKKGEWV 80


>UniRef50_D2RM01 SAF domain protein n=3 Tax=Bacteria RepID=D2RM01_ACIFE
          Length = 100

 Score = 49.3 bits (116), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 21/53 (39%), Positives = 36/53 (67%), Gaps = 1/53 (1%)

Query: 43 LELIEHIPQGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWI-DESMVVLP 94
          +E +E+IP  HK+AL D+P   E+I+YGE++G     + RG W+ D+++  +P
Sbjct: 38 VEALENIPFCHKIALTDLPEGSEVIKYGELLGKTNAPVARGHWVSDKNIFSVP 90


>UniRef50_UPI00017F2C45 Altronate dehydratase n=2 Tax=Enterobacteriaceae
           RepID=UPI00017F2C45
          Length = 119

 Score = 48.1 bits (113), Expect = 8e-04,   Method: Composition-based stats.
 Identities = 39/128 (30%), Positives = 54/128 (42%), Gaps = 22/128 (17%)

Query: 15  YIKVHDTDNVAIIVNDNGLKAGTRFP---DGLELIEHIPQGHKVALLDIPANGEIIRYGE 71
           YIK+H  DNVA+ + D  L  GT        + L + + +GHK AL +I     +I+YG 
Sbjct: 3   YIKIHALDNVAVALAD--LAEGTEVSVDNQTVRLRQDVARGHKFALTNIAKGANVIKYGL 60

Query: 72  VIGYAVRAIPRGSWID--------ESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGY 123
            IGYA+  I  G  +           +      P  H LP      E          + Y
Sbjct: 61  PIGYALADIAAGEHVHAHNTRTNLSDLDQYRYQPDFHDLPAQAADRE---------VQIY 111

Query: 124 RNADGSVG 131
           R A+G VG
Sbjct: 112 RRANGDVG 119


>UniRef50_D1Y192 Mannonate dehydratase n=1 Tax=Pyramidobacter piscolens W5455
          RepID=D1Y192_9BACT
          Length = 89

 Score = 47.8 bits (112), Expect = 0.001,   Method: Composition-based stats.
 Identities = 25/72 (34%), Positives = 39/72 (54%), Gaps = 1/72 (1%)

Query: 16 IKVHDTDNVAIIVNDNGLKAGTRFPDG-LELIEHIPQGHKVALLDIPANGEIIRYGEVIG 74
          +++   DNV  ++ D+        PDG L L++ +   HKV + D+ A   +I+YGE IG
Sbjct: 6  LQISPADNVKTVLEDSFRGDTIDTPDGPLTLLDDVEFAHKVLIKDLHAGDPVIKYGEEIG 65

Query: 75 YAVRAIPRGSWI 86
                PRG+WI
Sbjct: 66 RVKADTPRGTWI 77


>UniRef50_C1XHK9 Altronate dehydratase n=2 Tax=Meiothermus RepID=C1XHK9_MEIRU
          Length = 118

 Score = 47.4 bits (111), Expect = 0.001,   Method: Composition-based stats.
 Identities = 27/75 (36%), Positives = 41/75 (54%), Gaps = 11/75 (14%)

Query: 21 TDNVAIIVNDNGLKAGTRF---------PDGLELIEHIPQGHKVALLDIPANGEIIRYGE 71
          TD+VA+ V D  LKAG               ++L+E IP GHK+AL D+P    +I YGE
Sbjct: 19 TDDVAVAVAD--LKAGEELVIHSLEGGQTHRVKLLEDIPLGHKIALRDMPEGHVVIEYGE 76

Query: 72 VIGYAVRAIPRGSWI 86
           +G   + + +G ++
Sbjct: 77 KVGRMTQPVKKGGYV 91


>UniRef50_A7VSH3 Putative uncharacterized protein n=1 Tax=Clostridium leptum DSM
          753 RepID=A7VSH3_9CLOT
          Length = 136

 Score = 46.6 bits (109), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 30/78 (38%), Positives = 43/78 (55%), Gaps = 10/78 (12%)

Query: 17 KVHDTDNVAIIVNDNGLKAGTRF------PDG--LELIEHIPQGHKVALLDIPANGEIIR 68
          +V   DNVA  + D  + AG+        P G  +E ++ IP GHK+AL DI     II+
Sbjct: 18 QVSAQDNVATALGD--IPAGSVSVTGDIGPQGKNIEALQEIPYGHKIALRDIKPGEFIIK 75

Query: 69 YGEVIGYAVRAIPRGSWI 86
          YG  I  A + IP+G+W+
Sbjct: 76 YGVKIAVATQDIPKGAWV 93


>UniRef50_B5J029 Putative uncharacterized protein n=1 Tax=Octadecabacter antarcticus
           307 RepID=B5J029_9RHOB
          Length = 122

 Score = 46.6 bits (109), Expect = 0.002,   Method: Composition-based stats.
 Identities = 31/88 (35%), Positives = 46/88 (52%), Gaps = 6/88 (6%)

Query: 154 KIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGL 213
           +I    LL  Y +VDGVV L H  GCG+A +     +  R +   +++PN G  V V GL
Sbjct: 14  EIAASRLLEDYASVDGVVALAHGTGCGMANSGWGFDILDRVLWGHAIHPNVGATVFV-GL 72

Query: 214 GCEKLQPERLLT-----GTDDVQAIPVE 236
           GCE +Q   + +     GTD   A+ ++
Sbjct: 73  GCEVMQIAGMQSHSGTAGTDRFHALTIQ 100


>UniRef50_A8MAM1 SAF domain protein n=5 Tax=cellular organisms RepID=A8MAM1_CALMQ
          Length = 106

 Score = 46.6 bits (109), Expect = 0.002,   Method: Composition-based stats.
 Identities = 30/88 (34%), Positives = 47/88 (53%), Gaps = 9/88 (10%)

Query: 6  IRQETPTAFYIKVHDTDNVAIIVNDNGLKAGT-------RFPDGLELIEHIPQGHKVALL 58
          ++ E+     I +  +DNVA+ + D  LK+G+            ++LI++IP GHK AL 
Sbjct: 1  MKAESTVKEAIVLSPSDNVAVALRD--LKSGSLITLDVGSLRLTVKLIDNIPFGHKFALK 58

Query: 59 DIPANGEIIRYGEVIGYAVRAIPRGSWI 86
          DIP    +++YG  IG A R I  G  +
Sbjct: 59 DIPKCSLVVKYGHTIGRAKRDIKAGEHV 86


>UniRef50_B4TB53 Hydrolase, UxaA family n=14 Tax=Bacteria RepID=B4TB53_SALHS
          Length = 96

 Score = 46.2 bits (108), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 29/76 (38%), Positives = 41/76 (53%), Gaps = 9/76 (11%)

Query: 18 VHDTDNVAIIVNDNGLKAG---TRFPDGLE----LIEHIPQGHKVALLDIPANGEIIRYG 70
          +H  D VA  +    LKAG   T F    E    L + +P GHK A+ D+P +GE+ +YG
Sbjct: 8  IHPQDCVATAIT--ALKAGETATMFVGEREISVVLHQDVPFGHKFAICDVPFHGEVYKYG 65

Query: 71 EVIGYAVRAIPRGSWI 86
          E IG A + I  G ++
Sbjct: 66 ESIGRATQEIKSGDYV 81


>UniRef50_C0CW84 Putative uncharacterized protein n=1 Tax=Clostridium
          asparagiforme DSM 15981 RepID=C0CW84_9CLOT
          Length = 96

 Score = 45.4 bits (106), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 31/79 (39%), Positives = 45/79 (56%), Gaps = 9/79 (11%)

Query: 16 IKVHDTDNVAIIVNDNGLKAGT----RFPDG----LELIEHIPQGHKVALLDIPANGEII 67
          +KV D DNVA +  + G++AG     R   G    +  ++ IP GHKVA+  I    +I+
Sbjct: 5  LKVSDLDNVATVFAE-GIQAGAEIEVRDKKGESVVIRALDPIPYGHKVAVRGIETGEQIM 63

Query: 68 RYGEVIGYAVRAIPRGSWI 86
          +YGE IG A RAI  G+ +
Sbjct: 64 KYGEEIGVASRAIAAGNHV 82


>UniRef50_B8FML5 SAF domain protein n=1 Tax=Desulfatibacillum alkenivorans AK-01
          RepID=B8FML5_DESAA
          Length = 88

 Score = 45.4 bits (106), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 2/73 (2%)

Query: 16 IKVHDTDNVAIIVNDNGLKAGTRFPDGL--ELIEHIPQGHKVALLDIPANGEIIRYGEVI 73
          I V+  DNVA+ + D G     R  + +    I  I   HKV L D+    ++I+YGE+I
Sbjct: 6  IMVNPADNVAVALEDIGQGEEVRVGEKVLCRTIADIAYSHKVLLKDLSEGEDVIKYGEII 65

Query: 74 GYAVRAIPRGSWI 86
          G A + + +G W+
Sbjct: 66 GQAAQDLKQGEWV 78


>UniRef50_C0GPG6 SAF domain protein n=1 Tax=Desulfonatronospira thiodismutans
          ASO3-1 RepID=C0GPG6_9DELT
          Length = 99

 Score = 44.7 bits (104), Expect = 0.009,   Method: Composition-based stats.
 Identities = 27/72 (37%), Positives = 37/72 (51%), Gaps = 5/72 (6%)

Query: 16 IKVHDTDNVAIIVNDNGLKAGTRFPDG-----LELIEHIPQGHKVALLDIPANGEIIRYG 70
          + ++  DNVA    D  +       D      +++ E +  GHK AL DI   G+II+YG
Sbjct: 6  VLINKDDNVATATKDLDVGEKVLVQDDDSTFEIQVKEPVTFGHKFALSDISQGGQIIKYG 65

Query: 71 EVIGYAVRAIPR 82
          EVIG A R I R
Sbjct: 66 EVIGVATRDISR 77


>UniRef50_A1HS78 Hydrolase, UxaA family n=2 Tax=Thermosinus carboxydivorans Nor1
          RepID=A1HS78_9FIRM
          Length = 103

 Score = 44.3 bits (103), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 21/40 (52%), Positives = 26/40 (65%)

Query: 47 EHIPQGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWI 86
          E IP GHK+AL +IPA   II+YGE IG A + I  G  +
Sbjct: 41 ERIPFGHKIALQNIPAGQPIIKYGETIGLATQDIQSGQHV 80


>UniRef50_B5JYR1 Altronate hydrolase n=1 Tax=Octadecabacter antarcticus 238
          RepID=B5JYR1_9RHOB
          Length = 88

 Score = 43.9 bits (102), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 28/73 (38%), Positives = 39/73 (53%), Gaps = 2/73 (2%)

Query: 14 FYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRYGEVI 73
            +K    DNVA +++D  L   T    G+ + + IP GHKVAL  I A   +I+YG VI
Sbjct: 12 LSLKTQAGDNVATLLDDQ-LDC-TLISGGMSVDQGIPFGHKVALAPIAAGETVIKYGVVI 69

Query: 74 GYAVRAIPRGSWI 86
          G+A   I  G  +
Sbjct: 70 GHAKTGIREGEHV 82


>UniRef50_B1B868 Altronate hydrolase n=7 Tax=cellular organisms RepID=B1B868_CLOBO
          Length = 99

 Score = 43.1 bits (100), Expect = 0.024,   Method: Composition-based stats.
 Identities = 30/80 (37%), Positives = 42/80 (52%), Gaps = 9/80 (11%)

Query: 14 FYIKVHDTDNVAIIVNDNGLKAGTR-----FPDGLELI--EHIPQGHKVALLDIPANGEI 66
          F +  ++ DNVA  V    L+ G       F D  +++    IP GHK AL  I  N EI
Sbjct: 4  FAVVTNEKDNVATTVK--YLRKGEEVVVDVFGDEQKILLNNDIPFGHKFALKSINENEEI 61

Query: 67 IRYGEVIGYAVRAIPRGSWI 86
          I+YGE IG A + I +G ++
Sbjct: 62 IKYGEEIGQATKNIKQGDYV 81


>UniRef50_Q9HIE8 Putative uncharacterized protein Ta1392 n=1 Tax=Thermoplasma
          acidophilum RepID=Q9HIE8_THEAC
          Length = 95

 Score = 43.1 bits (100), Expect = 0.025,   Method: Composition-based stats.
 Identities = 28/72 (38%), Positives = 37/72 (51%), Gaps = 7/72 (9%)

Query: 22 DNVAIIVND--NGLKAGTRFPDGLE-----LIEHIPQGHKVALLDIPANGEIIRYGEVIG 74
          D+VA+  +D   G +    F D  E       E IP GHK++L DI     +I YGEVIG
Sbjct: 14 DSVAVATDDLKEGEEIQVAFLDNNEKTKITTAEVIPLGHKISLKDIKKGENVIEYGEVIG 73

Query: 75 YAVRAIPRGSWI 86
           A + I RG  +
Sbjct: 74 AATKDIKRGEHV 85


>UniRef50_C0CYJ4 Putative uncharacterized protein n=1 Tax=Clostridium
          asparagiforme DSM 15981 RepID=C0CYJ4_9CLOT
          Length = 101

 Score = 42.7 bits (99), Expect = 0.034,   Method: Composition-based stats.
 Identities = 28/92 (30%), Positives = 47/92 (51%), Gaps = 6/92 (6%)

Query: 9  ETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDG-----LELIEHIPQGHKVALLDIPAN 63
          ET     + + +TDNV   V +        +  G     +E +E IP  HK+AL+     
Sbjct: 2  ETGKINALMMEETDNVVTCVMEIKKGDAVVYRKGDTYCTVEALEDIPYCHKIALIPFDEG 61

Query: 64 GEIIRYGEVIGYAVRAIPRGSWID-ESMVVLP 94
           E+++YGE+IG   RAI +G  ++ E++  +P
Sbjct: 62 DEVVKYGEMIGRTNRAIGKGCLVNHENIYSVP 93


>UniRef50_D1U489 SAF domain protein n=1 Tax=Desulfovibrio aespoeensis Aspo-2
          RepID=D1U489_9DELT
          Length = 99

 Score = 42.7 bits (99), Expect = 0.035,   Method: Compositional matrix adjust.
 Identities = 20/41 (48%), Positives = 28/41 (68%)

Query: 46 IEHIPQGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWI 86
          ++ IP G K A+ DIPA+G+II+Y EV+G A R I  G  +
Sbjct: 40 VDEIPFGFKAAVKDIPASGDIIKYKEVVGQAGRDIRAGECV 80


>UniRef50_C8ZXV8 D-galactarate dehydratase n=1 Tax=Enterococcus gallinarum EG2
          RepID=C8ZXV8_ENTGA
          Length = 99

 Score = 42.0 bits (97), Expect = 0.060,   Method: Composition-based stats.
 Identities = 28/91 (30%), Positives = 46/91 (50%), Gaps = 7/91 (7%)

Query: 1  MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLEL-----IEHIPQGHKV 55
          M+  ++RQ   TA  ++    DNVA+++     ++     +   L     ++ I   HK 
Sbjct: 1  MSEEKVRQSMYTALMMR--PEDNVAVVLQPTPAESFVNIVNQASLNEFLIVQSIDSYHKF 58

Query: 56 ALLDIPANGEIIRYGEVIGYAVRAIPRGSWI 86
          ++ DI    EII+YGEVIG A  AI +G  +
Sbjct: 59 SVKDIEFGEEIIKYGEVIGIATAAIAKGEHV 89


>UniRef50_Q6L322 Altronate hydrolase n=1 Tax=Picrophilus torridus
          RepID=Q6L322_PICTO
          Length = 98

 Score = 41.6 bits (96), Expect = 0.066,   Method: Composition-based stats.
 Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 9/76 (11%)

Query: 18 VHDTDNVAIIVNDNGLKAGTRFP-DGL----ELI--EHIPQGHKVALLDIPANGEIIRYG 70
          + + DNVA ++   G KAG +    GL     +I  + IP GHK+A+ +I     +I+YG
Sbjct: 10 IDEKDNVATLLE--GSKAGEKVQLKGLTCEKSIICNQDIPSGHKIAIKNIKLGESVIKYG 67

Query: 71 EVIGYAVRAIPRGSWI 86
          E+IG A + I  G ++
Sbjct: 68 EIIGRATKEIKIGDYV 83


>UniRef50_B8G2E2 SAF domain protein n=2 Tax=Desulfitobacterium hafniense
          RepID=B8G2E2_DESHD
          Length = 103

 Score = 41.6 bits (96), Expect = 0.085,   Method: Compositional matrix adjust.
 Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 9/76 (11%)

Query: 18 VHDTDNVAIIVNDNGLKAGTRFP-------DGLELIEHIPQGHKVALLDIPANGEIIRYG 70
          +++ DNVA  V+   + AGT          + L + + IP GHKVAL+ I  +  +++YG
Sbjct: 8  IYEKDNVATCVDH--IPAGTTISFFRGSQAESLTVCQDIPLGHKVALIPIAQSSHVVKYG 65

Query: 71 EVIGYAVRAIPRGSWI 86
          E IG A   I  G  +
Sbjct: 66 ESIGAATIDIQPGQHV 81


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_P39829 D-galactarate dehydratase n=231 Tax=cellular org...   689   0.0  
UniRef50_C1ZG32 Altronate dehydratase n=1 Tax=Planctomyces limno...   596   e-169
UniRef50_A5FZN2 Galactarate dehydratase n=111 Tax=Bacteria RepID...   590   e-167
UniRef50_A6W5I2 Altronate dehydratase n=32 Tax=Bacteria RepID=A6...   583   e-165
UniRef50_D2QZ01 Altronate dehydratase n=1 Tax=Pirellula staleyi ...   583   e-165
UniRef50_C4X086 Altronate hydrolase n=14 Tax=Bacteria RepID=C4X0...   581   e-164
UniRef50_O34673 Altronate hydrolase n=80 Tax=Bacteria RepID=UXAA...   580   e-164
UniRef50_A9KNI4 Altronate dehydratase n=3 Tax=Clostridiales RepI...   579   e-163
UniRef50_A6VSK2 Altronate dehydratase n=7 Tax=Proteobacteria Rep...   579   e-163
UniRef50_P42604 Altronate hydrolase n=77 Tax=Bacteria RepID=UXAA...   577   e-163
UniRef50_Q028V7 Altronate dehydratase n=1 Tax=Candidatus Solibac...   571   e-161
UniRef50_Q21ZN4 Galactarate dehydratase n=8 Tax=Proteobacteria R...   570   e-161
UniRef50_D0ZBA7 Altronate hydrolase n=15 Tax=Bacteria RepID=D0ZB...   570   e-161
UniRef50_A7Z3M9 UxaA n=20 Tax=Bacteria RepID=A7Z3M9_BACA2             564   e-159
UniRef50_D1BWK3 Galactarate dehydratase n=1 Tax=Xylanimonas cell...   561   e-158
UniRef50_Q7UKI4 Altronate hydrolase n=2 Tax=Planctomycetales Rep...   556   e-157
UniRef50_C5SJY8 Altronate dehydratase n=3 Tax=Proteobacteria Rep...   553   e-156
UniRef50_D0D8F8 D-galactarate dehydratase n=2 Tax=Rhodobacterace...   552   e-155
UniRef50_C9B1P2 Altronate dehydratase n=9 Tax=Bacteria RepID=C9B...   551   e-155
UniRef50_A0RPU2 Altronate hydrolase n=10 Tax=Bacteria RepID=A0RP...   550   e-155
UniRef50_D2QEC5 Altronate dehydratase n=2 Tax=Sphingobacteriales...   535   e-150
UniRef50_B0T3J7 Altronate dehydratase n=15 Tax=Bacteria RepID=B0...   532   e-149
UniRef50_C1NB77 Altronate dehydratase n=2 Tax=Enterobacteriaceae...   531   e-149
UniRef50_C4STJ6 Altronate dehydratase n=1 Tax=Yersinia frederiks...   530   e-149
UniRef50_UPI0001C34772 Altronate dehydratase n=1 Tax=Providencia...   529   e-148
UniRef50_A0M231 Altronate hydrolase n=9 Tax=Bacteria RepID=A0M23...   524   e-147
UniRef50_C6J327 Altronate dehydratase n=1 Tax=Paenibacillus sp. ...   517   e-145
UniRef50_C7PV23 Altronate dehydratase n=13 Tax=Bacteria RepID=C7...   517   e-145
UniRef50_B5FMP6 Hydrolase, UxaA family n=75 Tax=cellular organis...   476   e-132
UniRef50_B0K1I9 Altronate dehydratase n=10 Tax=Firmicutes RepID=...   459   e-127
UniRef50_Q5WIY9 Altronate hydrolase C-terminus n=5 Tax=Firmicute...   454   e-126
UniRef50_Q6L323 Altronate hydrolase n=1 Tax=Picrophilus torridus...   446   e-123
UniRef50_Q1AYL8 D-galactarate dehydratase/Altronate hydrolase-li...   437   e-121
UniRef50_D1Y174 D-galactarate dehydratase (GalcD) n=3 Tax=Bacter...   432   e-119
UniRef50_C0CW83 Putative uncharacterized protein n=1 Tax=Clostri...   430   e-119
UniRef50_D1Y193 Galactarate dehydratase n=1 Tax=Pyramidobacter p...   426   e-118
UniRef50_A9V9F3 Predicted protein n=1 Tax=Monosiga brevicollis R...   420   e-116
UniRef50_B8FML6 Altronate dehydratase n=1 Tax=Desulfatibacillum ...   405   e-111
UniRef50_A8RT57 Putative uncharacterized protein n=1 Tax=Clostri...   404   e-111
UniRef50_D2PZR0 D-galactarate dehydratase/Altronate hydrolase do...   403   e-110
UniRef50_C9KKM7 Hydrolase, UxaA family n=1 Tax=Mitsuokella multa...   402   e-110
UniRef50_D2S1M0 Altronate dehydratase n=1 Tax=Haloterrigena turk...   398   e-109
UniRef50_C5EFV8 Hydrolase n=1 Tax=Clostridiales bacterium 1_7_47...   395   e-108
UniRef50_B1M8U1 Altronate dehydratase n=55 Tax=root RepID=B1M8U1...   389   e-106
UniRef50_B5IW17 D-galactarate dehydratase / Altronate hydrolase,...   387   e-106
UniRef50_Q0KC73 D-Galactarate dehydratase n=4 Tax=Burkholderiale...   384   e-105
UniRef50_C5EF38 Altronate dehydratase n=2 Tax=Clostridiales RepI...   383   e-104
UniRef50_A7VSH2 Putative uncharacterized protein n=1 Tax=Clostri...   382   e-104
UniRef50_Q13SA4 Altronate dehydratase n=48 Tax=Bacteria RepID=Q1...   379   e-103
UniRef50_A8H9C8 D-galactarate dehydratase/Altronate hydrolase do...   340   6e-92
UniRef50_B6WWW3 Putative uncharacterized protein n=2 Tax=Desulfo...   338   4e-91
UniRef50_D0Z3R7 Altronate hydrolase n=2 Tax=Bacteria RepID=D0Z3R...   323   8e-87
UniRef50_B5JYR2 D-Galactarate dehydratase n=1 Tax=Octadecabacter...   316   1e-84
UniRef50_D2S1L8 Altronate dehydratase-like protein n=1 Tax=Halot...   265   2e-69
UniRef50_C8T5I2 D-galactarate dehydratase n=3 Tax=Enterobacteria...   212   2e-53
UniRef50_B7DPM4 Altronate dehydratase n=1 Tax=Alicyclobacillus a...   172   4e-41
UniRef50_UPI00017F2C45 Altronate dehydratase n=2 Tax=Enterobacte...   129   2e-28
UniRef50_UPI00017F3110 galactarate dehydratase n=1 Tax=Escherich...   127   1e-27
UniRef50_C5EFR7 Predicted protein n=1 Tax=Clostridiales bacteriu...    97   1e-18
UniRef50_C2DK38 Putative uncharacterized protein n=2 Tax=Escheri...    95   8e-18
UniRef50_Q0RXU4 Possible sulfolactate sulfo-lyase small subunit ...    94   1e-17
UniRef50_D1Y192 Mannonate dehydratase n=1 Tax=Pyramidobacter pis...    93   3e-17
UniRef50_B9MJB7 SMP-30/Gluconolaconase/LRE domain protein n=1 Ta...    89   4e-16
UniRef50_C1XHK9 Altronate dehydratase n=2 Tax=Meiothermus RepID=...    87   1e-15
UniRef50_C5EF39 Altronate hydrolase n=3 Tax=Clostridiales RepID=...    87   1e-15
UniRef50_D2RM01 SAF domain protein n=3 Tax=Bacteria RepID=D2RM01...    77   2e-12

Sequences not found previously or not previously below threshold:

UniRef50_B9TLG0 Putative uncharacterized protein (Fragment) n=1 ...   140   2e-31
UniRef50_A8MAM1 SAF domain protein n=5 Tax=cellular organisms Re...    97   2e-18
UniRef50_A7VSH3 Putative uncharacterized protein n=1 Tax=Clostri...    90   2e-16
UniRef50_B4D086 SAF domain protein n=1 Tax=Chthoniobacter flavus...    89   4e-16
UniRef50_B8FML5 SAF domain protein n=1 Tax=Desulfatibacillum alk...    87   1e-15
UniRef50_D2PG65 SAF domain protein n=15 Tax=cellular organisms R...    86   3e-15
UniRef50_Q5WIZ0 Altronate hydrolase N-terminus n=5 Tax=Bacteria ...    83   2e-14
UniRef50_Q9HIE8 Putative uncharacterized protein Ta1392 n=1 Tax=...    83   3e-14
UniRef50_B4TB53 Hydrolase, UxaA family n=14 Tax=Bacteria RepID=B...    83   3e-14
UniRef50_C8ZXV8 D-galactarate dehydratase n=1 Tax=Enterococcus g...    82   4e-14
UniRef50_Q6L322 Altronate hydrolase n=1 Tax=Picrophilus torridus...    82   4e-14
UniRef50_C0GPG6 SAF domain protein n=1 Tax=Desulfonatronospira t...    81   1e-13
UniRef50_D2NF82 Truncated altronate dehydratase n=2 Tax=Escheric...    81   1e-13
UniRef50_C3WAI6 Carbohydrate hydrolase n=2 Tax=Bacteria RepID=C3...    80   2e-13
UniRef50_B8IQB2 SAF domain protein n=8 Tax=Proteobacteria RepID=...    80   2e-13
UniRef50_B8FVM2 SAF domain protein n=4 Tax=Desulfitobacterium ha...    80   3e-13
UniRef50_Q3ACL1 Hydrolase, UxaA family n=1 Tax=Carboxydothermus ...    80   3e-13
UniRef50_B1B868 Altronate hydrolase n=7 Tax=cellular organisms R...    80   3e-13
UniRef50_B5JYR1 Altronate hydrolase n=1 Tax=Octadecabacter antar...    79   4e-13
UniRef50_C0D6Q5 Putative uncharacterized protein n=1 Tax=Clostri...    79   4e-13
UniRef50_D2QGM2 Putative uncharacterized protein n=1 Tax=Spiroso...    79   5e-13
UniRef50_B5J029 Putative uncharacterized protein n=1 Tax=Octadec...    78   6e-13
UniRef50_B8G2E2 SAF domain protein n=2 Tax=Desulfitobacterium ha...    78   9e-13
UniRef50_C5SG41 SAF domain protein n=1 Tax=Asticcacaulis excentr...    78   1e-12
UniRef50_A1HS78 Hydrolase, UxaA family n=2 Tax=Thermosinus carbo...    77   1e-12
UniRef50_Q184J3 Probable carbohydrate hydrolase (N-terminus) n=5...    77   2e-12
UniRef50_C0CW84 Putative uncharacterized protein n=1 Tax=Clostri...    75   5e-12
UniRef50_B6BQ17 D-galactarate dehydratase/Altronate n=2 Tax=root...    75   5e-12
UniRef50_A1WPF7 SAF domain n=4 Tax=Burkholderiales RepID=A1WPF7_...    75   5e-12
UniRef50_B3PBS2 Hydrolase, UxaA family n=2 Tax=Proteobacteria Re...    74   1e-11
UniRef50_D2S1L9 SAF domain protein n=1 Tax=Haloterrigena turkmen...    74   1e-11
UniRef50_B2T9V7 SAF domain protein n=33 Tax=Burkholderia RepID=B...    73   2e-11
UniRef50_D1Y7V9 Mannonate dehydratase n=1 Tax=Pyramidobacter pis...    73   3e-11
UniRef50_B8IYJ4 SAF domain protein n=5 Tax=Proteobacteria RepID=...    72   4e-11
UniRef50_C9XPT3 Altronate hydrolase (N-terminus) n=4 Tax=Clostri...    72   5e-11
UniRef50_A4GAA3 Altronate dehydratase (N part) n=3 Tax=Proteobac...    70   2e-10
UniRef50_B0PEC9 Putative uncharacterized protein n=1 Tax=Anaerot...    70   3e-10
UniRef50_Q1QWP1 D-galactarate dehydratase/Altronate hydrolase-li...    69   3e-10
UniRef50_B8DQ83 D-galactarate dehydratase/altronate hydrolase-li...    69   4e-10
UniRef50_Q2G5K6 D-galactarate dehydratase/Altronate hydrolase-li...    69   4e-10
UniRef50_Q1ASX0 Altronate hydrolase n=1 Tax=Rubrobacter xylanoph...    68   1e-09
UniRef50_B0T1B9 D-galactarate dehydratase/altronate hydrolase-li...    67   2e-09
UniRef50_Q0RXW3 Putative uncharacterized protein n=1 Tax=Rhodoco...    64   1e-08
UniRef50_B0K1I8 SAF domain n=9 Tax=Thermoanaerobacterales RepID=...    64   1e-08
UniRef50_C0CYJ4 Putative uncharacterized protein n=1 Tax=Clostri...    64   1e-08
UniRef50_D1U489 SAF domain protein n=1 Tax=Desulfovibrio aespoee...    64   2e-08
UniRef50_A8H9C9 D-galactarate dehydratase n=4 Tax=Proteobacteria...    63   2e-08
UniRef50_Q58Y44 Sulfolactate sulfo-lyase small subunit n=1 Tax=P...    63   2e-08
UniRef50_B5J028 Putative uncharacterized protein n=1 Tax=Octadec...    52   6e-05
UniRef50_Q4HS65 Putative uncharacterized protein n=1 Tax=Campylo...    49   5e-04

>UniRef50_P39829 D-galactarate dehydratase n=231 Tax=cellular organisms
           RepID=GARD_ECOLI
          Length = 523

 Score =  689 bits (1777), Expect = 0.0,   Method: Composition-based stats.
 Identities = 523/523 (100%), Positives = 523/523 (100%)

Query: 1   MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDI 60
           MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDI
Sbjct: 1   MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDI 60

Query: 61  PANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTF 120
           PANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTF
Sbjct: 61  PANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTF 120

Query: 121 EGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCG 180
           EGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCG
Sbjct: 121 EGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCG 180

Query: 181 VAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASI 240
           VAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASI
Sbjct: 181 VAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASI 240

Query: 241 VSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTAN 300
           VSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTAN
Sbjct: 241 VSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTAN 300

Query: 301 PAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGK 360
           PAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGK
Sbjct: 301 PAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGK 360

Query: 361 TDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDF 420
           TDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDF
Sbjct: 361 TDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDF 420

Query: 421 VCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEE 480
           VCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEE
Sbjct: 421 VCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEE 480

Query: 481 TIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAPVT 523
           TIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAPVT
Sbjct: 481 TIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAPVT 523


>UniRef50_C1ZG32 Altronate dehydratase n=1 Tax=Planctomyces limnophilus DSM 3776
           RepID=C1ZG32_PLALI
          Length = 526

 Score =  596 bits (1537), Expect = e-169,   Method: Composition-based stats.
 Identities = 190/528 (35%), Positives = 281/528 (53%), Gaps = 20/528 (3%)

Query: 10  TPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIP--QGHKVALLDIPANGEII 67
           +     +++   D+VA+   +  L AG+   +G EL+   P   GHKVALL I A   I+
Sbjct: 3   SEPPRLLQLSPVDHVAVATQN--LPAGSVTHEGQELLIRQPVRAGHKVALLPIAAGTPIL 60

Query: 68  RYGEVIGYAVRAIPRGSWIDESMVVL-------PEAPPLHTLPLATKVPEPLPPLEG-YT 119
           +YG+    A R I  G  +    V +         A P        +   P   +E   T
Sbjct: 61  KYGQPFAIASRDILAGEHVHTHNVRVMGPEDCQQLAKPNSASSSHDRSTSPTTHVENEMT 120

Query: 120 FEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGC 179
           F G R  DG V T+N + +  +V+C + VV  +V+ I +DLL +Y NVDGV+ L H  GC
Sbjct: 121 FAGIRRPDGRVATRNYVAVIGTVNCSSTVVRKIVRAISQDLLNQYENVDGVIPLVHSGGC 180

Query: 180 GVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIP----V 235
            +           R +   + +PN G  ++V GLGCE  Q   L+     VQ        
Sbjct: 181 AMEFGGTDHRQLARILGGYARHPNIGAYLLV-GLGCETGQGSFLIEQEGLVQLRRSGEVQ 239

Query: 236 ESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFS 295
           +SA  + +  ++  G +  +E  L   +  L + N+ QRE+ PASELV+G++CGGSD FS
Sbjct: 240 QSAPPLLVNIQEAGGVRRTIERALAALKELLPEANKCQRESIPASELVMGLKCGGSDGFS 299

Query: 296 GVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNY 355
           G+TANPA+G ASDLL+  G T + +E  E+    HLL  R+++ EV ++LL+++ W+  Y
Sbjct: 300 GLTANPALGVASDLLISQGGTALLAETPEIFGGEHLLASRSIDSEVSQKLLDKVAWWRAY 359

Query: 356 LNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAAT 415
                T    NPS GNK+GGL  +VEK+LG+I K G S +V+VL   +R   RGL +  +
Sbjct: 360 AAKFGTTLDGNPSFGNKEGGLTTIVEKSLGAITKGGASPLVDVLDYAERVRHRGLNFMDS 419

Query: 416 PASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTI 475
           P  D    T  +ASG  V  FTTGRG+ +G    P +K++T T L  R  + MD +AG +
Sbjct: 420 PGYDPASVTGLIASGAHVVCFTTGRGSCFGSKPAPTLKISTNTSLFERLSEEMDFDAGRV 479

Query: 476 ATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLH-NQLAVFNPAPV 522
            +G  +I + G  L   +L VASG+K T S+Q G   ++   + P PV
Sbjct: 480 LSG-ASISQTGQNLLRKVLKVASGEK-TCSEQQGFGDDEFFPWTPGPV 525


>UniRef50_A5FZN2 Galactarate dehydratase n=111 Tax=Bacteria RepID=A5FZN2_ACICJ
          Length = 538

 Score =  590 bits (1522), Expect = e-167,   Method: Composition-based stats.
 Identities = 193/521 (37%), Positives = 282/521 (54%), Gaps = 18/521 (3%)

Query: 7   RQETP---TAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDIPAN 63
           R  T        ++++D DNV + +    + +GT   +GL     IP+GHK+A   I A 
Sbjct: 30  RNGTRPMNAPTTVRLNDADNVLVAIE--PIASGTGVAEGLVTSARIPRGHKIASAPIEAG 87

Query: 64  GEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGY 123
             + ++G++IG+A  AI  G+W+ E  V + E    +TL     V     P    TF G+
Sbjct: 88  APVRKFGQIIGFAKEAIAPGAWVHEHNVEVHEFARDYTLGEVKPVEPAAAPA---TFMGF 144

Query: 124 RNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIER-DLLPKYPNVDGVVGLNHLYGCGVA 182
           R A+G VGT+N + I +SV+C A V   +    ER  LL  +PNVDG+V L H  GCG+A
Sbjct: 145 RRANGQVGTRNYIAILSSVNCAATVARQIALRAERSGLLDGFPNVDGIVPLTHGTGCGMA 204

Query: 183 INAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVS 242
            +     +  RT+   + NPN  G V+ IGLGCE LQ  R+                   
Sbjct: 205 ADGEGYELLERTLWGAACNPNVAG-VLFIGLGCEVLQIARMTARYGLKDDPRFH-----W 258

Query: 243 LQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPA 302
           +  +   G  + +E  L      L + +  +RE  PAS L++ +QCGGSDA+SG+TANPA
Sbjct: 259 MTIQDSGGTPATIEAGLAALREILPRADAARREPLPASHLILALQCGGSDAYSGLTANPA 318

Query: 303 VGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTD 362
           +G A+D+LVR G T + SE  E+  A HLL  RA +  V   LL  ++W+ +YL      
Sbjct: 319 LGEAADILVRHGGTAILSETPEIYGAEHLLVHRAASRRVADDLLARIDWWRDYLARTGGQ 378

Query: 363 RSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVC 422
            + NPSPGNK GGL  ++EK+LG++AK G + +  V    +  T+RG ++  TP  D V 
Sbjct: 379 MNNNPSPGNKAGGLTTILEKSLGAVAKGGTTPLTAVYRYAEPVTERGFVFMDTPGYDPVS 438

Query: 423 GTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETI 482
            T QVA G  +  FTTGRG+ +G   VP IK+AT ++L  R    MDI+ G I +G  TI
Sbjct: 439 VTGQVAGGANILCFTTGRGSAFGCKPVPSIKLATNSDLYRRMETDMDIDCGDILSG-TTI 497

Query: 483 EEVGWKLFHFILDVASGKKKTFSDQWGLHN-QLAVFNPAPV 522
            + G ++F  +LDVASG + T S++ G  + +   +    V
Sbjct: 498 AQKGEEIFRHLLDVASGAR-TKSERLGYGDNEFVPWQVGAV 537


>UniRef50_A6W5I2 Altronate dehydratase n=32 Tax=Bacteria RepID=A6W5I2_KINRD
          Length = 533

 Score =  583 bits (1503), Expect = e-165,   Method: Composition-based stats.
 Identities = 197/530 (37%), Positives = 277/530 (52%), Gaps = 28/530 (5%)

Query: 12  TAFYIKVHDTDNVAIIVNDNGLKAGTRFP-------DGLELIEHIPQGHKVALLDIPANG 64
            A  +++   D VA+      L AGT            L +   +P GHKVAL D+ A  
Sbjct: 12  AAPLLRLAPGDTVAVA--REALAAGTAVDLAALGEAGALTVRTDVPAGHKVALRDVAAGE 69

Query: 65  EIIRYGEVIGYAVRAIPRGSWIDESMVVLP---------EAPPLHTLPLATKVPEP-LPP 114
            + +YG++IG A   I  G  +    +            +A P          P P +PP
Sbjct: 70  AVRKYGQLIGLASAPIAAGEHVHVHNLAFTASQAGAGSADAGPGGYAVGVDARPTPLVPP 129

Query: 115 LEGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIE-RDLLPKYPNVDGVVGL 173
            E  TF+G   ADG V T+N +GI TSV+C A     +         L  YPNVDGVV L
Sbjct: 130 AERRTFDGIVRADGRVATRNYIGILTSVNCSATAARRIADTFRWPGALDAYPNVDGVVAL 189

Query: 174 NHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAI 233
            H  GCG+      A +  RTI   + +PNF   ++VIGLGCE  Q   L +G D    +
Sbjct: 190 THGTGCGMDALGEGAQLLRRTISGYARHPNFAA-LLVIGLGCEVNQVAALTSGFDLPPEV 248

Query: 234 PVESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDA 293
           PV     V++  ++  G    V   ++     L  ++  +R   PASELV+G+ CGGSDA
Sbjct: 249 PV-----VAMTIQEIGGTTRTVAAGVERVRELLPVVDAVRRVPVPASELVLGLNCGGSDA 303

Query: 294 FSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYD 353
           +SGVTANPA+G ASDLLV  G T + +E  EV  A HLLT RA + EV  +L+  + W++
Sbjct: 304 WSGVTANPALGVASDLLVAQGGTSVLAETPEVYGAEHLLTRRARDPEVAAKLVRRIRWWE 363

Query: 354 NYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYA 413
            Y          NPSPGNK GGL  ++EK+LG++AK G +A+  V    +  T +G  + 
Sbjct: 364 EYTAAHGGSMDNNPSPGNKAGGLTTILEKSLGAVAKGGSAALEAVYEYAEPITAKGFTFM 423

Query: 414 ATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAG 473
            TP  D V  T  VA G  V  FTTGRG+ +G    P IK+AT +E+  R  + MD++ G
Sbjct: 424 DTPGYDPVSVTGLVAGGANVVCFTTGRGSVFGCKPAPSIKLATNSEVYARMDEDMDVDCG 483

Query: 474 TIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHN-QLAVFNPAPV 522
            + TGE+T+EE G +LF  IL+VASG++   S++ G+ + +   +    V
Sbjct: 484 RVLTGEQTVEEAGRELFELILEVASGRRS-KSEELGVGDEEFQPWQLGAV 532


>UniRef50_D2QZ01 Altronate dehydratase n=1 Tax=Pirellula staleyi DSM 6068
           RepID=D2QZ01_9PLAN
          Length = 516

 Score =  583 bits (1503), Expect = e-165,   Method: Composition-based stats.
 Identities = 187/515 (36%), Positives = 273/515 (53%), Gaps = 11/515 (2%)

Query: 11  PTAFYIKVHDTDNVAIIVNDNGLKAGTRFP---DGLELIEHIPQGHKVALLDIPANGEII 67
            T   I +H +DN+ +      L AG +       + L   I  GHK+A+  I     + 
Sbjct: 7   RTTPAIYLHPSDNICVAAR--TLDAGLKLDIAATTITLSSLIKIGHKIAIAPIAKGSFVY 64

Query: 68  RYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNAD 127
           +YG++IG A   I  G  +      L     +     +  +P  LPP+   TF GYR AD
Sbjct: 65  KYGQIIGTATCDIAPGDHVHSHN--LTNGDFVRDYAKSQAIPAALPPITDRTFLGYRRAD 122

Query: 128 GSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPA 187
           G  GT+N + + ++V+C A V  Y+    ++ +L  YP++DGV+ L H  GCG+      
Sbjct: 123 GKAGTRNYIAVISTVNCSASVSKYIANRFDQSILKDYPSIDGVIALKHGGGCGLQYGGLQ 182

Query: 188 AVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEK 247
             +  RT+  ++ +PN GG  ++IGLGCE      LL     +Q    +      L  + 
Sbjct: 183 HQILARTLGGMAKHPNIGGF-LLIGLGCENAPMGYLLDSQKLIQIDGNKRNMPPVLSMQD 241

Query: 248 HVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYAS 307
             G    VE  +++    L K    +R   PASE+++G  CGGSD  SGVT NPA+G AS
Sbjct: 242 LGGTAKTVEAGIRMLGELLPKAADVKRVPIPASEIILGTNCGGSDGNSGVTCNPALGVAS 301

Query: 308 DLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANP 367
           DLLVRCG T   +E TE+  A HLLT RA   EV  +LLE ++W+  +  M   +   NP
Sbjct: 302 DLLVRCGGTTALAETTEIYGAEHLLTRRARTPEVADKLLERIDWWLWHTKMYGVEIDNNP 361

Query: 368 SPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQV 427
           S GNK+GGL  + EK+LG++AK+G +A+ EV    +  T +G +   TP  D    T  V
Sbjct: 362 SVGNKEGGLTTIAEKSLGAVAKTGTTALEEVYHYAEPMTAKGFVVMDTPGFDPPSVTGLV 421

Query: 428 ASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGW 487
           A G  V VFTTGRG+ +G   VP IK+A+ T +  R  D MDIN+G +  G +++E  G 
Sbjct: 422 AGGANVVVFTTGRGSCFGCKPVPSIKVASNTPMYERMIDDMDINSGEVLHG-QSLEAAGQ 480

Query: 488 KLFHFILDVASGKKKTFSDQWGLHN-QLAVFNPAP 521
           ++F  IL VASG+K T S+Q G+ + +   +   P
Sbjct: 481 EIFEKILSVASGEK-TKSEQHGIGDEEFVPWQVGP 514


>UniRef50_C4X086 Altronate hydrolase n=14 Tax=Bacteria RepID=C4X086_KLEPN
          Length = 495

 Score =  581 bits (1497), Expect = e-164,   Method: Composition-based stats.
 Identities = 150/508 (29%), Positives = 237/508 (46%), Gaps = 18/508 (3%)

Query: 14  FYIKVHDTDNVAIIVNDNGLKAGTRFP-DGLELIEHIPQGHKVALLDIPANGEIIRYGEV 72
            YIK+H  DNVA+ + D    +      D + L + I +GHK AL  I     +++YG  
Sbjct: 2   QYIKIHSQDNVAVALTDIAAGSVVTIDNDSVTLGQDIVRGHKFALRAIAKGENVVKYGLP 61

Query: 73  IGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVGT 132
           IG+A+  I  G  +            L        +    P       + YR A+G VG 
Sbjct: 62  IGHALADIAPGEHVHAHNTR-TNLSDLDAYRYQPDLVAQPPQPADREVQIYRRANGDVGV 120

Query: 133 KNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPI 192
           +N L I  +V CV  +   +     ++      ++DGV   +H YGC    +       +
Sbjct: 121 RNELWILPTVGCVNAMARQMQNRFLKET-YGAEDIDGVHLFSHTYGCSQLGDDHINTRTM 179

Query: 193 RTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQ 252
             + N+  +PN  G V+V+GLGCE  Q E       +     V         DE      
Sbjct: 180 --LQNMVRHPN-AGAVLVVGLGCENNQVEAFRETLGEFDPQRVHFMVCQHQDDE------ 230

Query: 253 SMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVR 312
             VE  ++   +  + + Q +R+    SEL  G++CGGSD  SG+TANP +G  SD ++ 
Sbjct: 231 --VEAGVEHLHQLYEVMRQDKRQPGKLSELKFGLECGGSDGLSGITANPMLGRFSDYVIA 288

Query: 313 CGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNK 372
            G T + +EV E+  A  LL     +E    +L+  +  +  Y          NPSPGNK
Sbjct: 289 NGGTTVLTEVPEMFGAEQLLMSHCRDEATFDKLVTMVNDFKQYFIAHDQPIYENPSPGNK 348

Query: 373 KGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGIT 432
            GG+  + +K+LG   K+G S +V+VL  G+R    GL   + P +D V  +    +G  
Sbjct: 349 AGGITTLEDKSLGCTQKAGSSQVVDVLRYGERLKVHGLNLLSAPGNDAVATSALAGAGCH 408

Query: 433 VQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHF 492
           + +F+TGRGTPYG   VP +K+AT +ELA +    +D +AG +  G +T+ ++  +    
Sbjct: 409 MVLFSTGRGTPYGG-FVPTVKIATNSELAAKKKHWIDFDAGQLLHG-KTMPQLLEEFVDA 466

Query: 493 ILDVASGKKKTFSDQWGLHNQLAVFNPA 520
           I+  A+GK     ++     +LA+F   
Sbjct: 467 IVAFANGKPTC--NEQNDFRELAIFKSG 492


>UniRef50_O34673 Altronate hydrolase n=80 Tax=Bacteria RepID=UXAA_BACSU
          Length = 497

 Score =  580 bits (1496), Expect = e-164,   Method: Composition-based stats.
 Identities = 164/509 (32%), Positives = 258/509 (50%), Gaps = 21/509 (4%)

Query: 15  YIKVHDTDNVAIIVNDNGLKAGTRFPD---GLELIEHIPQGHKVALLDIPANGEIIRYGE 71
           +IK+H  DNV + + D  ++ G R       +E+ + I +GHK+AL  I  N  I++YG 
Sbjct: 4   FIKIHKQDNVLLALRD--IQKGERLHAYGVSIEVKDDIKRGHKIALQSIKENDSIVKYGF 61

Query: 72  VIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVG 131
            IG+A + I  G  I            +       +  E     E  TF+G+R  +G  G
Sbjct: 62  PIGHASQDISIGEHIHVHNTK-TNLSDIQLYSYTPRFDENPYSNENRTFKGFRRENGDAG 120

Query: 132 TKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVP 191
            +N L I  +V CV G+ + +++   R+     P  D V+ L H YGC    +       
Sbjct: 121 VRNELWIVPTVGCVNGIAEKMLQRFVRETGDIAP-FDNVLVLKHQYGCSQLGDDHENTKQ 179

Query: 192 IRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGF 251
           I  + N   +PN GG V+V+GLGCE  +  R+     DV    V+     S+ DE     
Sbjct: 180 I--LLNAIRHPNAGG-VLVLGLGCENNELARMKEALQDVNLKRVKFLESQSVTDE----- 231

Query: 252 QSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLV 311
              +E  + + +   +     +RE  P SEL +G++CGGSD FSG+TANP +G  SD L+
Sbjct: 232 ---MEAGVALLKEIHEAAKGDKREDIPLSELKIGLKCGGSDGFSGITANPLLGRFSDYLI 288

Query: 312 RCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGN 371
             G + + +EV E+  A  +L  RA NEEV  ++++ +  +  Y          NPSPGN
Sbjct: 289 AQGGSTVLTEVPEMFGAETILMQRAANEEVFHKIVDLINDFKQYFIKHDQPVYENPSPGN 348

Query: 372 KKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGI 431
           K GG++ + +K+LG   K+G S + +VL  G+    +GL   + P +D +  +   A+G 
Sbjct: 349 KAGGISTLEDKSLGCTQKAGISPVTDVLKYGEVLKTKGLTLLSAPGNDLIASSALAAAGC 408

Query: 432 TVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFH 491
            + +FTTGRGTP+G   VP +K+AT TEL       +D NAG +A  +   E V  +  H
Sbjct: 409 QIVLFTTGRGTPFGT-FVPTVKVATNTELYEAKPHWIDFNAGLLAEDDVHEEYVLREFIH 467

Query: 492 FILDVASGKKKTFSDQWGLHNQLAVFNPA 520
           ++++VASG+    + +     +LA+F   
Sbjct: 468 YMIEVASGQL--VNHEKNDFKELAIFKSG 494


>UniRef50_A9KNI4 Altronate dehydratase n=3 Tax=Clostridiales RepID=A9KNI4_CLOPH
          Length = 493

 Score =  579 bits (1492), Expect = e-163,   Method: Composition-based stats.
 Identities = 167/507 (32%), Positives = 264/507 (52%), Gaps = 21/507 (4%)

Query: 15  YIKVHDTDNVAIIVNDNGLKAGTRFPD-GLELIEHIPQGHKVALLDIPANGEIIRYGEVI 73
           ++K++  DNVA+ +ND             + L+E IP+GHK  L ++     +++YG  I
Sbjct: 4   FVKINSKDNVAVALNDLTKGMTIEVDGVAVTLVEDIPRGHKFTLANLNEGENVLKYGFPI 63

Query: 74  GYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVGTK 133
           G+  +A   GSW+    +       L T      V + L P E  TF GYR  +G VG +
Sbjct: 64  GHLTKAAEMGSWVHTQNIK-TNLGELLTYSYEPNVNQ-LKPHEKATFMGYRRDNGKVGIR 121

Query: 134 NLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIR 193
           N + I  +V CV  + + + K  +  L     +V+ ++   H YGC    +       I 
Sbjct: 122 NEVWIIPTVGCVNKIAEAMEKQFKEKLT---GSVEDIIAFPHPYGCSQMGDDQENTRII- 177

Query: 194 TIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQS 253
            + ++  +PN    V+V+GLGCE      L     +     ++      ++DE       
Sbjct: 178 -LSDLINHPNAAA-VLVLGLGCENTNIAELKKYIGEYDEDRIKFLQCQDVEDE------- 228

Query: 254 MVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRC 313
            +E   ++ E+ +    + +RE   A ELV+GM+CGGSD  SG+TANP VG  SDLL+  
Sbjct: 229 -MEVAEELIEQLISYAAKFEREPISADELVIGMKCGGSDGMSGITANPTVGVFSDLLISQ 287

Query: 314 GATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKK 373
           G T + +EV E+  A  LL  R  NEE+  + ++ +  + NY          NPSPGNKK
Sbjct: 288 GGTTVLTEVPEMFGAETLLMARCENEELFDKTVDMINDFKNYFKSHNQTIYENPSPGNKK 347

Query: 374 GGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITV 433
           GG++ + +K+LG   KSG + + +VL  G+    +GL   + P +D V  T   ASG  +
Sbjct: 348 GGISTLEDKSLGCTQKSGSAPVKDVLKYGEIVKTKGLNLLSAPGNDLVASTALAASGAHM 407

Query: 434 QVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFI 493
            +FTTGRGTP+    VP +K++T T LA +  + +D N GT+  G +T++ +G +LF ++
Sbjct: 408 VLFTTGRGTPFASP-VPTMKISTNTPLAMKKNNWIDFNCGTLVEG-KTLDILGEELFQYV 465

Query: 494 LDVASGKKKTFSDQWGLHNQLAVFNPA 520
           L VASGKK   S++ G H+ +A+F   
Sbjct: 466 LAVASGKK-VKSEEAGFHD-MAIFKSG 490


>UniRef50_A6VSK2 Altronate dehydratase n=7 Tax=Proteobacteria RepID=A6VSK2_MARMS
          Length = 509

 Score =  579 bits (1492), Expect = e-163,   Method: Composition-based stats.
 Identities = 165/517 (31%), Positives = 270/517 (52%), Gaps = 11/517 (2%)

Query: 9   ETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPD-GLELIEHIPQGHKVALLDIPANGEII 67
            + ++  IK+H  DNV I+     +  G + P+  L +   +  GHK+A   I A   II
Sbjct: 2   SSSSSPLIKLHSNDNVCIV--RESVSIGQQVPEFNLRIRAQVSGGHKIAARLIEAGEPII 59

Query: 68  RYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNAD 127
           +Y   IG A+R I  G  +    + L +     +        + +      TF G   ++
Sbjct: 60  KYDTRIGVALRRIEAGDHVHTHNLELVDYERDPSFCQDVVPVDYVDVSARATFNGIVRSN 119

Query: 128 GSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPA 187
           G V T+N +GI ++V+C + V+  +      + L  +PNVDG+V   H  GCG++  +  
Sbjct: 120 GKVATRNYIGILSTVNCSSTVIRQIADHFTPERLSAFPNVDGIVAFPHTSGCGMSSPSYH 179

Query: 188 AVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEK 247
             V  RT+   + +PN  G V+++GLGCE+ +   L+      +      + + +L  + 
Sbjct: 180 FDVLRRTLSGYARHPNLAG-VLIVGLGCERNEMSSLIASQQLEEN-----SHLQTLVMQA 233

Query: 248 HVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYAS 307
             G ++ +   +   E  L + N+  RE      L +G+QCGGSD FS +TANPA+G A 
Sbjct: 234 VGGTRATIAAGIAAIESMLPEANKVVREPVSVEHLKIGLQCGGSDGFSAITANPALGMAM 293

Query: 308 DLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANP 367
           D+LVR G T + SE  E+    ++LT RA+++EVG++LL+ + W+D Y        +   
Sbjct: 294 DILVRHGGTAILSETPEIHGVEYMLTRRAISQEVGQKLLDRLSWWDEYTRGHNGQFNGVV 353

Query: 368 SPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQV 427
             GN+ GGLAN+ EK+LGS  K G + +  V    +   + G ++  TP  D V  T Q+
Sbjct: 354 GQGNQAGGLANIFEKSLGSAMKGGTTPLQAVYEYAEPIEQNGFVFMDTPGYDPVSATGQI 413

Query: 428 ASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGW 487
           A G  +  FTTGRG+ +G    P IK+A+ + + NR  + MDIN G I  G+ ++EE+G 
Sbjct: 414 AGGANLICFTTGRGSMFGSKPAPTIKLASNSNMYNRLQEDMDINCGLILDGKMSLEEMGQ 473

Query: 488 KLFHFILDVASGKKKTFSDQWGLHN-QLAVFNPAPVT 523
            +F  I+ VASG+  T S++ GL + +   ++   V+
Sbjct: 474 HIFEHIIKVASGE-STSSERLGLGDNEFIPWHIGIVS 509


>UniRef50_P42604 Altronate hydrolase n=77 Tax=Bacteria RepID=UXAA_ECOLI
          Length = 495

 Score =  577 bits (1487), Expect = e-163,   Method: Composition-based stats.
 Identities = 153/510 (30%), Positives = 237/510 (46%), Gaps = 22/510 (4%)

Query: 14  FYIKVHDTDNVAIIVNDNGLKAGTRFP---DGLELIEHIPQGHKVALLDIPANGEIIRYG 70
            YIK+H  DNVA+ + D  L  GT        + L + + +GHK AL DI     +I+YG
Sbjct: 2   QYIKIHALDNVAVALAD--LAEGTEVSVDNQTVTLRQDVARGHKFALTDIAKGANVIKYG 59

Query: 71  EVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSV 130
             IGYA+  I  G  +            L          +          + YR A+G V
Sbjct: 60  LPIGYALADIAAGVHVHAHNTR-TNLSDLDQYRYQPDFQDLPAQAADREVQIYRRANGDV 118

Query: 131 GTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVV 190
           G +N L I  +V CV G+   +     ++        DGV   +H YGC    +      
Sbjct: 119 GVRNELWILPTVGCVNGIARQIQNRFLKET-NNAEGTDGVFLFSHTYGCSQLGDDHINTR 177

Query: 191 PIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVG 250
            +  + N+  +PN  G V+VIGLGCE  Q         D+    V         DE    
Sbjct: 178 TM--LQNMVRHPN-AGAVLVIGLGCENNQVAAFRETLGDIDPERVHFMICQQQDDE---- 230

Query: 251 FQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLL 310
               +E  ++   +    +   +RE    SEL  G++CGGSD  SG+TANP +G  SD +
Sbjct: 231 ----IEAGIEHLHQLYNVMRNDKREPGKLSELKFGLECGGSDGLSGITANPMLGRFSDYV 286

Query: 311 VRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPG 370
           +  G T + +EV E+  A  LL     +E   ++L+  +  +  Y          NPSPG
Sbjct: 287 IANGGTTVLTEVPEMFGAEQLLMDHCRDEATFEKLVTMVNDFKQYFIAHDQPIYENPSPG 346

Query: 371 NKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASG 430
           NK GG+  + +K+LG   K+G S +V+VL  G+R    GL   + P +D V  +    +G
Sbjct: 347 NKAGGITTLEDKSLGCTQKAGSSVVVDVLRYGERLKTPGLNLLSAPGNDAVATSALAGAG 406

Query: 431 ITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLF 490
             + +F+TGRGTPYG   VP +K+AT +ELA +    +D +AG +  G+  + ++  +  
Sbjct: 407 CHMVLFSTGRGTPYGG-FVPTVKIATNSELAAKKKHWIDFDAGQLIHGKA-MPQLLEEFI 464

Query: 491 HFILDVASGKKKTFSDQWGLHNQLAVFNPA 520
             I++ A+GK+    ++     +LA+F   
Sbjct: 465 DTIVEFANGKQTC--NERNDFRELAIFKSG 492


>UniRef50_Q028V7 Altronate dehydratase n=1 Tax=Candidatus Solibacter usitatus
           Ellin6076 RepID=Q028V7_SOLUE
          Length = 511

 Score =  571 bits (1473), Expect = e-161,   Method: Composition-based stats.
 Identities = 187/511 (36%), Positives = 268/511 (52%), Gaps = 18/511 (3%)

Query: 15  YIKVHDTDNVAIIVNDNGLKAGTRFP-DGL--ELIEHIPQGHKVALLDIPANGEIIRYGE 71
            I +H TDNVA+      L AGT    DGL   + + IP GHK+AL DI     + RYG+
Sbjct: 15  VIHLHPTDNVAVA--RVPLPAGTELRVDGLPVTVRDAIPAGHKIALWDIAPGETVERYGQ 72

Query: 72  VIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVG 131
           VIG A   I  G  I    +   E    +  P  T+   P P  +  TF GY   DG VG
Sbjct: 73  VIGRAKLPIDAGRHIHTHNLAYEELALDYEFPT-TETAVPTPRPDAPTFLGYPREDGRVG 131

Query: 132 TKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVP 191
           T+N + +  + +C A   + + +  E   LP  PNVDGVV   H  GCG A   P     
Sbjct: 132 TRNYIAVVAASNCAAHAAELIARSYEGVTLP--PNVDGVVAFPHGEGCGHAF-GPDVDQL 188

Query: 192 IRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGF 251
            RT+  + ++PN     +++GLGCE  Q +  L               +V +  +   G 
Sbjct: 189 RRTLGGVLVHPNVSA-ALILGLGCEVNQIDHYLGAGSPRTNR------LVGMTLQTSGGT 241

Query: 252 QSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLV 311
             ++    +   R  ++     R   PAS++++G+ CGGSD+FSG+TANPA+G+ SDLL 
Sbjct: 242 PGILAAARREIGRFFEQAAAENRVPVPASKIILGLNCGGSDSFSGITANPALGFCSDLLA 301

Query: 312 RCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGN 371
             GA  + +E  E+  A HLL  RA N E+  +LL  +  Y  YL+        NPSPGN
Sbjct: 302 ELGAASVLAETPEIFGAEHLLVRRARNREIADKLLGCISRYKKYLSRFDGSFDDNPSPGN 361

Query: 372 KKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGI 431
           K+GGL+N++EK+LG++AK G S +++V    ++ T  G  +  TP  D V  T   A G 
Sbjct: 362 KEGGLSNILEKSLGAVAKGGTSPLIDVYEYAEKITAPGFSFMNTPGYDPVSLTGLAAGGC 421

Query: 432 TVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFH 491
            +  FTTGRG+  G   +PVIK++T T       D MDINAG IA GE TI++ G ++FH
Sbjct: 422 NLIAFTTGRGSAIGFPTIPVIKISTNTHTYRAMPDNMDINAGAIADGESTIQQTGREIFH 481

Query: 492 FILDVASGKKKTFSDQWGLHNQLAVFNPAPV 522
            +L +ASG + T +++ G H +   +   PV
Sbjct: 482 ALLAIASG-RPTCAERLG-HKEFVPWRIGPV 510


>UniRef50_Q21ZN4 Galactarate dehydratase n=8 Tax=Proteobacteria RepID=Q21ZN4_RHOFD
          Length = 509

 Score =  570 bits (1469), Expect = e-161,   Method: Composition-based stats.
 Identities = 182/517 (35%), Positives = 266/517 (51%), Gaps = 15/517 (2%)

Query: 12  TAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRYGE 71
               I++H  D+V I   +  +       + + +   IP GHK+A  +I     + RYG+
Sbjct: 3   APAAIRLHINDDVVIA-RNQLISGTLIAQESVTVQGLIPAGHKMATRNIAEGEAVRRYGQ 61

Query: 72  VIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVG 131
           +IG+A R I  G  +    + + +           +  + +P  E   F+G    DG V 
Sbjct: 62  IIGFASRPIMAGQHVHVHNLSIGDFN--RDYAYGKESVDTVPATEAAFFQGIVRGDGRVA 119

Query: 132 TKNLLGITTSVHCVAGVVDYVVKIIERDLLPK----YPNVDGVVGLNHLYGCGVAINAPA 187
           T+N +GI TSV+C A V   +     RD+ P+    YPNVDGVV L H  GC +      
Sbjct: 120 TRNYIGILTSVNCSATVARAIADHFRRDIHPEALAAYPNVDGVVALTHGVGCAIDPQGEG 179

Query: 188 AVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEK 247
             V  RT+   + + NF   V++IGLGCE  Q   LL      + + +      +   + 
Sbjct: 180 LAVLQRTLGGYACHANF-ASVLIIGLGCETNQISDLLATQGLKENVRLH-----TFTIQD 233

Query: 248 HVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYAS 307
             G    ++  +   +  L   N  QR+T  AS LVVG+QCGGSD +SG++ANP +G A 
Sbjct: 234 TGGTVKTIQHGIDRIQEMLPAANAVQRQTVSASHLVVGLQCGGSDGYSGISANPVLGAAV 293

Query: 308 DLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANP 367
           DLLVR G T + SE  E+  A HLLT RAV   VG++L++ + W++++          NP
Sbjct: 294 DLLVRQGGTAILSETPEIYGAEHLLTRRAVTPAVGEKLVQRIRWWEDHCKRNGASMDNNP 353

Query: 368 SPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQV 427
           S GNK GGL  V+EK+LG IAK G + +VEV    Q    +GL++  TP  D +  T QV
Sbjct: 354 SSGNKAGGLTTVLEKSLGGIAKGGSTNLVEVYEYAQPVRAQGLVFMDTPGYDPISATGQV 413

Query: 428 ASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGW 487
           A G  +  FTTGRG+ YG    P +K+AT T L  R  D MDIN G +  G  TI E+G 
Sbjct: 414 AGGANLICFTTGRGSAYGCAPTPSLKLATNTALWQRQADDMDINCGDVLDGSATIAELGQ 473

Query: 488 KLFHFILDVASGKKKTFSDQWGLH-NQLAVFNPAPVT 523
           + F  +L+ ASG++   S+  G   N+   +  + +T
Sbjct: 474 RFFQMMLETASGRQS-RSELHGYGQNEFVPWQLSVIT 509


>UniRef50_D0ZBA7 Altronate hydrolase n=15 Tax=Bacteria RepID=D0ZBA7_EDWTE
          Length = 496

 Score =  570 bits (1469), Expect = e-161,   Method: Composition-based stats.
 Identities = 151/506 (29%), Positives = 238/506 (47%), Gaps = 18/506 (3%)

Query: 16  IKVHDTDNVAIIVNDNGLKAGTRFPDG-LELIEHIPQGHKVALLDIPANGEIIRYGEVIG 74
           IK+H  DNVA+ + D          DG L L + +P+GHKVAL  +     +I+YG  IG
Sbjct: 5   IKIHPQDNVAVALRDLAAGETIALDDGALTLRDAVPRGHKVALCHLAPQAMVIKYGLPIG 64

Query: 75  YAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVGTKN 134
           +A+  I  G  +    +       L +         P           YR A G V  +N
Sbjct: 65  HALTPIAAGDHVHAQNLR-TNLSDLDSYQYQPDFAAPTAQPADRAISLYRRASGEVAIRN 123

Query: 135 LLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRT 194
            L I  +V CV G+   +++   R+       +DGV    H +GC    +       +  
Sbjct: 124 ELWILPTVGCVNGMARQMLQRFLRES-DGASAIDGVHLFTHPFGCSQLGDDHQNTRTL-- 180

Query: 195 IHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSM 254
           + N+  +PN GG V+V+GLGCE  Q         D     V         DE   G +++
Sbjct: 181 LQNMVHHPNAGG-VLVVGLGCENNQIAAFRETLGDYDPARVRFLVCQQQDDEVEAGTEAL 239

Query: 255 VEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCG 314
            E            +   +RE    SEL  G++CGGSD FSG++ANP +G  SD ++  G
Sbjct: 240 HE--------LYGAMRGDRREPGRLSELKFGLECGGSDGFSGISANPLLGRFSDYVIAHG 291

Query: 315 ATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKG 374
            T + +EV E+  A  +L  R  + E  ++ +  +  +  Y    +     NPSPGNK G
Sbjct: 292 GTSVLTEVPEMFGAERILMSRCRDGETFEKTVAMVNDFKRYFIDHQQPIYENPSPGNKAG 351

Query: 375 GLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQ 434
           G+  + EK+LG   K+G+S +++VL  G+R    GL   + P +D V  +   A+G  + 
Sbjct: 352 GITTLEEKSLGCTQKAGQSQVMDVLRYGERLHTPGLNLLSAPGNDAVATSALAAAGCHMV 411

Query: 435 VFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFIL 494
           +F+TGRGTPYG   VP +K+AT T LA +    +D +AG +  G + +  +  +    I+
Sbjct: 412 LFSTGRGTPYGG-FVPTVKLATNTPLAAKKPHWIDFDAGQLLQG-KPMALLLSEFIDLIV 469

Query: 495 DVASGKKKTFSDQWGLHNQLAVFNPA 520
            +A G++    ++     +LA+F   
Sbjct: 470 AIADGRQTC--NEKNDFRELAIFKSG 493


>UniRef50_A7Z3M9 UxaA n=20 Tax=Bacteria RepID=A7Z3M9_BACA2
          Length = 497

 Score =  564 bits (1454), Expect = e-159,   Method: Composition-based stats.
 Identities = 158/509 (31%), Positives = 255/509 (50%), Gaps = 21/509 (4%)

Query: 15  YIKVHDTDNVAIIVNDNGLKAGTRFP-DGLE--LIEHIPQGHKVALLDIPANGEIIRYGE 71
            IK+H  DNV + +       G R   DGL   + + + +GHK+AL  I  NG II+YG 
Sbjct: 4   VIKIHKNDNVLLAMR--HFDKGERLHTDGLTIEVKDPVKRGHKIALQTIEENGSIIKYGF 61

Query: 72  VIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVG 131
            IG A R I  G  I    +       +     + +  +     E  TF+GYR  +G+ G
Sbjct: 62  SIGRATRRISAGEHIHTHNLQ-TNLSDVQEYTYSPRFEDNPFTNENRTFKGYRRENGTSG 120

Query: 132 TKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVP 191
            +N L I  +V CV GV + +++   ++     P  D V+ L H YGC    +       
Sbjct: 121 VRNELWIVPTVGCVNGVAEKILQRFVKEAKDIAP-FDNVLVLKHQYGCSQLGDDHENTKQ 179

Query: 192 IRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGF 251
           +  + N   +PN GG V+V+GLGCE  +   +     +V    V+     ++ DE     
Sbjct: 180 M--LMNAIRHPNAGG-VLVLGLGCENNELAAIKETLSEVNGDRVKFLESQAVTDE----- 231

Query: 252 QSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLV 311
              +E    + +         +RE  P SEL +G++CGGSD FSG+TANP +G  SD L+
Sbjct: 232 ---IEAGTALLKEIHLAAKGDKREEIPLSELSIGLKCGGSDGFSGITANPLLGRFSDYLI 288

Query: 312 RCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGN 371
             G + + +EV E+  A  +L  RA +EEV  + +  +  +  Y    +     NPSPGN
Sbjct: 289 AQGGSTVLTEVPEMFGAETILMQRAASEEVFHKTVRLINDFKQYFMKHEQPIYENPSPGN 348

Query: 372 KKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGI 431
           K+GG++ + +K+LG   K+G + + +VL+ G+    +GL   + P +D +  +   A+G 
Sbjct: 349 KEGGISTLEDKSLGCTQKAGLAPVSDVLTYGETLKTKGLTLLSAPGNDLIASSALAAAGC 408

Query: 432 TVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFH 491
            + +FTTGRGTP+G   VP +K++T T+L       +D NAG +A  + T + +      
Sbjct: 409 HIVLFTTGRGTPFGT-FVPTVKVSTNTDLFQSKPHWIDYNAGRLAEDQTTEDHIVRDFIQ 467

Query: 492 FILDVASGKKKTFSDQWGLHNQLAVFNPA 520
           +I+ VASG+    +++     +LA+F   
Sbjct: 468 YIIKVASGE--FVNNEKNDFRELAIFKSG 494


>UniRef50_D1BWK3 Galactarate dehydratase n=1 Tax=Xylanimonas cellulosilytica DSM
           15894 RepID=D1BWK3_XYLCX
          Length = 533

 Score =  561 bits (1447), Expect = e-158,   Method: Composition-based stats.
 Identities = 196/538 (36%), Positives = 283/538 (52%), Gaps = 33/538 (6%)

Query: 14  FYIKVHDTDNVAIIVNDNGLKAGTRFPDG---LELIEHIPQGHKVALLDIPANGEIIRYG 70
             + +H  D+VA+   D  L AG     G   +     +P+GHKVA+ D+P    + +YG
Sbjct: 1   MLLLLHPDDDVAVATRD--LAAGETLDAGARTITTTGPVPRGHKVAVADLPPGAPVHKYG 58

Query: 71  EVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSV 130
           +VIG A   +  G  +    +        H L   T     +P     TF+GYR ADG V
Sbjct: 59  QVIGVATAPLAAGEHVHAHNLGFEAGHRDHQLG-GTHTELAVPAGPRPTFQGYRRADGRV 117

Query: 131 GTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVV 190
           GT+N + I TSV+C A     +        L  YPNVDGV+ L H  GCG+  ++    +
Sbjct: 118 GTRNYVAILTSVNCSATTARMIAAQFGPQALAGYPNVDGVIALTHQSGCGLVPSSEGGQI 177

Query: 191 PIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLT-------------GTDDVQAIPV-- 235
            +RT+   + +PN  G V+V+GLGCE +  E+L T             GT    A PV  
Sbjct: 178 LLRTLRGYAAHPNIAG-VLVLGLGCEMVLTEQLTTRSGTGAFLGMPGVGTPPPPADPVLA 236

Query: 236 ---ESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSD 292
                  + SL  ++  G ++ V   +   ER L  ++ R+RE C  ++LV+ + CGGSD
Sbjct: 237 DIPADTVVESLTIQESGGVRAAVTAGVAAVERMLAVVDTRRREICDVADLVLALNCGGSD 296

Query: 293 AFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWY 352
            +SG+TANPA+G+ASD LV  GAT   +E  EV  A HLLT RAV  +V +RLL+ ++W+
Sbjct: 297 GYSGLTANPALGWASDRLVAYGATSALAETPEVFGAEHLLTRRAVTPQVAQRLLDRIDWW 356

Query: 353 DNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRP-TKRGLI 411
            +Y   G      NPSPGNK GGL  ++EK+LG++AK G++ +  V    +R   + G +
Sbjct: 357 QDYTRAGGGSMDNNPSPGNKAGGLTTILEKSLGAVAKGGQADLAAVYEYAERMAPRGGFV 416

Query: 412 YAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDIN 471
           +  TP  D V  T  VA G  V VFTTGRG+ +G    P IK+AT T +     D MD++
Sbjct: 417 FMDTPGYDPVSVTGLVAGGSNVVVFTTGRGSVFGCRPTPSIKVATNTPMYRAMSDDMDVD 476

Query: 472 AGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGL------HNQLAVFNPAPVT 523
           AG I  GE T+E+VG ++   IL VASG+  T S+   +        +   ++   VT
Sbjct: 477 AGRIVEGEATVEQVGQEILDLILRVASGEP-TVSEDLQIAGVTIGAEEFVPWHVGAVT 533


>UniRef50_Q7UKI4 Altronate hydrolase n=2 Tax=Planctomycetales RepID=Q7UKI4_RHOBA
          Length = 634

 Score =  556 bits (1433), Expect = e-157,   Method: Composition-based stats.
 Identities = 175/526 (33%), Positives = 262/526 (49%), Gaps = 24/526 (4%)

Query: 15  YIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRYGEVIG 74
            +++HD DNV +      L AG    +       +P GHKVA   IPA   +I++G+ IG
Sbjct: 114 VVRLHDGDNVWMAAW--ALVAGETIGNLRIAGSAVPAGHKVAAQAIPAGELVIKFGQPIG 171

Query: 75  YAVRAIPRGSWIDESMVVLPEAPPLHT-------LPLATKVPEPLPPLEGYTFEGYRNAD 127
            A   I  G  +    +V                   +    +P  P E  TFEG+   D
Sbjct: 172 KASCDIGVGEHVHSHNLVDAHQVDSDWRSLVGTAFSKSAPAKKPAVPAEK-TFEGFVRPD 230

Query: 128 GSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPA 187
           G VGT+N + I   V+C A V  +V      + L ++PNVDG+    H  GC +      
Sbjct: 231 GQVGTRNYVQILARVNCSATVCHHVAARFPPERLAEFPNVDGIAIGTHTTGCALRYAGQK 290

Query: 188 AVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLT-----GTDDVQAIPV-----ES 237
             +  R +   + + N  G  + IGLGCE+  PE L          D +++PV     ES
Sbjct: 291 QQMLGRVLKGYAGHANV-GSCLTIGLGCEQTTPEYLSEHHQLVAISDPRSLPVTSPESES 349

Query: 238 ASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGV 297
            S   L  +   G ++ ++   +  E  L+  NQ  R T PA  L + ++CGGSD  SG 
Sbjct: 350 VSTTMLTMQAEGGTRATIDRAEKHLETMLEIANQNSRTTVPAHHLRLALECGGSDGHSGW 409

Query: 298 TANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLN 357
           TANP VG  +D +V  G   + SE TE+  A HLL  R+ +E V +RL+++++W+  ++ 
Sbjct: 410 TANPLVGAIADRMVAFGGAAVLSETTELIGAEHLLVARSRDESVAQRLMDKVDWWKKHVA 469

Query: 358 MGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPA 417
           M   +   NPS GNK GGL  + EK+LG+++KSG   +  VL       K+GL    +P 
Sbjct: 470 MYGGEIDNNPSIGNKAGGLTTITEKSLGAVSKSGTGILDGVLDYADTVPKQGLYVMDSPG 529

Query: 418 SDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIAT 477
            D    T +VA G  + +FTTGRG+ +G   VPVIK+A+ + L +   D MD NAG +  
Sbjct: 530 FDPSSVTGKVAGGCNLVLFTTGRGSCFGGKPVPVIKIASHSTLFHAMRDDMDWNAGQLLE 589

Query: 478 GEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHN-QLAVFNPAPV 522
           G   +EE+  +LF  +L  ASG + T S++ GL + +   +   PV
Sbjct: 590 G-VAMEELADQLFEELLRFASGTQ-TASERLGLGDHEFVPWTVGPV 633


>UniRef50_C5SJY8 Altronate dehydratase n=3 Tax=Proteobacteria RepID=C5SJY8_9CAUL
          Length = 515

 Score =  553 bits (1424), Expect = e-156,   Method: Composition-based stats.
 Identities = 171/512 (33%), Positives = 263/512 (51%), Gaps = 27/512 (5%)

Query: 14  FYIKVHDTDNVAIIVNDNGLKAGTRFPDG---LELIEHIPQGHKVALLDIPANGEIIRYG 70
            Y++VH TD+VAI V    L AG     G   L L   IP+GHK+AL DI     ++++G
Sbjct: 23  RYVRVHATDDVAIAVE--ALSAGEVLDFGDVQLTLGTDIPKGHKIALRDIAEGAPVLKFG 80

Query: 71  EVIGYAVRAIPRGSWIDESMVV--LPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADG 128
             IG+A+  I  G  +    +   L         P+A + P   P  +  TF GYR ADG
Sbjct: 81  FRIGHAIAPIKTGEHVHTHNLSTSLTGVEDYDYAPVAAEGPGSRP--DARTFMGYRRADG 138

Query: 129 SVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAA 188
            VG +N + I  +V CVA   + + K+       +   VDGV  L H  GC    +    
Sbjct: 139 RVGIRNEIWILCTVGCVARTSERLAKVASERFKGR---VDGVYALTHPLGCSQLGDDLNH 195

Query: 189 VVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKH 248
               + +  ++ +PN GG V+++GLGCE  Q   L+   +      ++  +   ++DE  
Sbjct: 196 TR--KLLAALAAHPNAGG-VLIVGLGCENNQLSALIGEIEGRTPDRLKYFAAQMVEDE-- 250

Query: 249 VGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASD 308
                  E  L+  E  +Q + + QRE C  S+L +G++CGGSD FSG+TANP VG  +D
Sbjct: 251 ------HESGLEALEALVQVVEKDQRELCHVSDLAIGVKCGGSDGFSGLTANPLVGRVAD 304

Query: 309 LLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPS 368
           ++   G   + +E+ EV  A  +L  RA +E V  ++++ +  +  Y          NPS
Sbjct: 305 IVALAGGQSIMTEIPEVFGAERILMARAKDEGVFHQIVDVVNDFKQYFLDNNQPVFENPS 364

Query: 369 PGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVA 428
           PGNK GG++ + EK+LG++ K G S + EVL  G+R T+ GL     P +D V  T   A
Sbjct: 365 PGNKAGGISTLEEKSLGAVQKGGLSQLTEVLRYGERATQAGLSLLEAPGNDAVSSTALTA 424

Query: 429 SGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWK 488
           +G  + +FTTGRGTP G    P +K+A+ T LA +    +D NAG    G +T++E    
Sbjct: 425 AGAVIVLFTTGRGTPLGFP-APTLKIASNTALAEKKPHWIDFNAGQALEG-KTLDETADD 482

Query: 489 LFHFILDVASGKKKTFSDQWGLHNQLAVFNPA 520
           L   IL VASG++   +++     ++A++   
Sbjct: 483 LMDLILRVASGER--ANNEKNDEREIAIWKNG 512


>UniRef50_D0D8F8 D-galactarate dehydratase n=2 Tax=Rhodobacteraceae
           RepID=D0D8F8_9RHOB
          Length = 498

 Score =  552 bits (1422), Expect = e-155,   Method: Composition-based stats.
 Identities = 179/512 (34%), Positives = 274/512 (53%), Gaps = 18/512 (3%)

Query: 12  TAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRYGE 71
               + +  TD VA++++D  + AG    DG+  +E IP+GHKVA   + A   +++YG+
Sbjct: 3   APTIMVLDPTDTVAVVLSD--MDAGET-RDGITALEAIPRGHKVARKAMKAGDPVLKYGQ 59

Query: 72  VIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVG 131
           V+  A   IP G+ +      LPE     +   A     P       TF+G+   DG VG
Sbjct: 60  VMAVASVDIPEGAHVHVQNCALPEGSHGISAAQARLPEAPTRN----TFQGFARPDGRVG 115

Query: 132 TKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVP 191
           T+N +G+  SV+C   V D +     R LLPKYPNVDG   + H  GCG+A         
Sbjct: 116 TRNYIGVIASVNCSTTVCDAIAAEANRTLLPKYPNVDGFAPIVHDQGCGMANKGEGFDAL 175

Query: 192 IRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGF 251
           + T+     +PNFGG V++IGLGCE  Q           +          +   ++  G 
Sbjct: 176 VLTLKGYRDHPNFGG-VLIIGLGCEVNQLTLYKPTEWTRER-------FKTFNIQEVGGS 227

Query: 252 QSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLV 311
           +S V+  L + E      N+  R   P S+L +GMQCGGSD FSG+TANPA+G ASD+LV
Sbjct: 228 RSAVKRALDLLEPIAAMANEDTRSEQPVSKLTLGMQCGGSDGFSGITANPALGVASDMLV 287

Query: 312 RCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGN 371
             G T + SE  E+  A HLL  RA +E  G+++ + + W+ +Y +        NPSPGN
Sbjct: 288 TAGGTSILSETPEIYGAEHLLIARA-DEATGQKIEDMIVWWRDYASKNGASLDNNPSPGN 346

Query: 372 KKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGI 431
           KKGGL  ++EK+LG++AK G + +    +  ++    G +Y  +P  D V  T QVASG 
Sbjct: 347 KKGGLTTILEKSLGAVAKGGLAPLSGAFAYSEKIDTHGFVYMDSPGYDPVAATGQVASGA 406

Query: 432 TVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFH 491
            +  FTTGRG+ +G    P IK+++ ++LA    + +DI+ G +     ++ E+G +++ 
Sbjct: 407 NLIAFTTGRGSCFGAKPAPSIKLSSNSQLARSMAEDIDIDCGGVVEQGVSLTEMGERIYD 466

Query: 492 FILDVASGKKKTFSDQWGLHN-QLAVFNPAPV 522
            +LDVASG +KT S+++G  + +   +    V
Sbjct: 467 LLLDVASG-RKTMSEEFGYGDNEFVPWKIGAV 497


>UniRef50_C9B1P2 Altronate dehydratase n=9 Tax=Bacteria RepID=C9B1P2_ENTCA
          Length = 503

 Score =  551 bits (1419), Expect = e-155,   Method: Composition-based stats.
 Identities = 168/513 (32%), Positives = 251/513 (48%), Gaps = 20/513 (3%)

Query: 9   ETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFP-DGLELIEHIPQGHKVALLDIPANGEII 67
           ETP A  +K+H  DNVA+ +     K    F    + L E IPQGHK+AL D+  + ++I
Sbjct: 7   ETP-AQLLKLHPKDNVAVALKPLAAKTTLAFEGQTITLFEDIPQGHKIALKDLAQSQDVI 65

Query: 68  RYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNAD 127
           +YG  IG+ +  +  G W+    V             A  +     P    TF+GYR A+
Sbjct: 66  KYGYPIGHLLTDVKTGQWLHTHNVK-TNLSGTLAYTYAPDLHPVRYPKRAATFQGYRRAN 124

Query: 128 GSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPA 187
           G VG +N L I  +V C+ G+ + +V+  +++  P     D +  L H YGC        
Sbjct: 125 GKVGIRNDLLIVPTVGCINGIAEIIVENFKKNH-PDLGTFDHITILKHPYGCSQLGQDHQ 183

Query: 188 AVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEK 247
               I  + +   +PN GG V+V GLGCE            D     V+        DE 
Sbjct: 184 NTRQI--LIDAVHHPNAGG-VLVFGLGCENNTVPEFKKNLGDYDPKRVKFMVAQESDDE- 239

Query: 248 HVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYAS 307
                  +     + E  L+   + QRE  P SEL +G++CGGSD FSG+TANP +G  S
Sbjct: 240 -------IAVGESLLEELLEAAKEDQREAVPLSELKIGLKCGGSDGFSGITANPLLGAFS 292

Query: 308 DLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANP 367
           D LV  G + + +EV E+  A  +L  RA +E   +++L  +  + +Y          NP
Sbjct: 293 DFLVSQGGSTVLTEVPEMFGAEQVLMARAQDEATFEKILHLINDFKDYFLAYGEPVYENP 352

Query: 368 SPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQV 427
           SPGNK GG+  + +K+LG   KSG SA+V+VL  G++  K GL     P +D V  +   
Sbjct: 353 SPGNKAGGITTLEDKSLGCTQKSGTSAVVDVLKYGEKLRKPGLSLLEGPGNDLVAASALA 412

Query: 428 ASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGW 487
           ++   + +FTTGRGTP+G   VP +K+AT  E+ ++    MD NAG +    E +E V  
Sbjct: 413 SADCQLVLFTTGRGTPFG-AYVPTMKVATNQEIYHKKPHWMDFNAGRLLE--EPMEVVLE 469

Query: 488 KLFHFILDVASGKKKTFSDQWGLHNQLAVFNPA 520
                I+D ASGK     ++     ++A+F   
Sbjct: 470 DFIQAIIDTASGKPT--RNEANNVREIAIFKNG 500


>UniRef50_A0RPU2 Altronate hydrolase n=10 Tax=Bacteria RepID=A0RPU2_CAMFF
          Length = 505

 Score =  550 bits (1417), Expect = e-155,   Method: Composition-based stats.
 Identities = 166/512 (32%), Positives = 268/512 (52%), Gaps = 20/512 (3%)

Query: 16  IKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRYGEVIGY 75
           I V + DN A  +    L        G+ +IE I +GHK A  DI     II+Y  +IG 
Sbjct: 4   IHVDEKDNAATALK---LIQKNSVELGVTIIEDISKGHKFATKDIKKGEAIIKYSSIIGI 60

Query: 76  AVRAIPRGSWIDESMVVLPEA-----PPLHTLPLA-TKVPEPLPPLEGYTFEGYRNADGS 129
           A + I +G+WI    +            LH          +     + Y  +GYR +DGS
Sbjct: 61  ANQDIKKGAWIHVHNIEGTRGRGDISGNLHIASQKLKNKKQAASNDKKYELQGYRRSDGS 120

Query: 130 VGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAV 189
            G +N + I  SVHC   VV+ +   I   L         +V + H +GC        A 
Sbjct: 121 FGLRNHILILPSVHCANKVVEKIAAAINYGLGLGNDECK-IVYVTHQHGCSQL--EFDAR 177

Query: 190 VPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHV 249
             + T+     NPN  G V+VIGLGCE +  + +     D          +     ++  
Sbjct: 178 QTMDTLVGNGANPNVYG-VLVIGLGCEVISAQNVAKEIKDRAPY----KEVEYFTIQQSG 232

Query: 250 GFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDL 309
           G +  +E  ++IA+  LQ   + ++     S+L++G +CGGSD+FSG++ANPA+G ASD+
Sbjct: 233 GTRKSIEKGIKIAKNMLQNALKFKKSRGDLSDLILGTECGGSDSFSGLSANPALGVASDI 292

Query: 310 LVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTD-RSANPS 368
           +++ G +V+ +E TE+  A H+L  R++NE++ ++++  +  ++  +   K D R ANPS
Sbjct: 293 VIQKGGSVILAETTELIGAEHILAARSINEDIKEQVISTITSFEQRVLDSKADIRGANPS 352

Query: 369 PGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVA 428
           PGN +GGL+++ EK+LG I K+G   ++ V    Q  T++GL    TP +D    +  VA
Sbjct: 353 PGNIEGGLSSIEEKSLGCIYKAGNQPVISVKRYAQPITQKGLTLMDTPGNDIEQLSAMVA 412

Query: 429 SGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWK 488
            G  + VFTTGRGTP G    P IK+++ + + +   D +DINAG+I  G++ I+EVG +
Sbjct: 413 GGCNICVFTTGRGTPTGSPITPTIKVSSNSAIYHNMNDAIDINAGSIIDGQKNIKEVGEE 472

Query: 489 LFHFILDVASGKKKTFSDQWGLHNQLAVFNPA 520
           +  FI+ +++GK  T ++Q    N  +V+  A
Sbjct: 473 ILDFIVAISNGK-LTKAEQ-NDQNDFSVWRLA 502


>UniRef50_D2QEC5 Altronate dehydratase n=2 Tax=Sphingobacteriales RepID=D2QEC5_9SPHI
          Length = 582

 Score =  535 bits (1378), Expect = e-150,   Method: Composition-based stats.
 Identities = 155/560 (27%), Positives = 238/560 (42%), Gaps = 60/560 (10%)

Query: 13  AFYIKVHDTDNVAIIVNDNGLKAGTRFPDGL-ELIEHIPQGHKVALLDIPANGEIIRYGE 71
           A  +KVH  DNV + + +        F + L EL   +   HK    D      I  YG 
Sbjct: 28  ARVLKVHPADNVIVALRNLAAGEKIEFENTLYELPYAVGAKHKFVTEDRQPGDPITMYGV 87

Query: 72  VIGYAVRAIPRGSWIDESMVVLP--EAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGS 129
           ++G A + I RG  I    +             P + + P  L   EG TF GY  ADGS
Sbjct: 88  LVGKATQPIRRGEPITTFNLKHDADTYGLDKKQPYSWQPPNTLA-WEGRTFMGYHRADGS 146

Query: 130 VGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYP------------------------ 165
           VGT+N   +   V C    V  +    ER+L    P                        
Sbjct: 147 VGTRNYWLVVPLVFCENRNVLILKDAFERELGYAQPETYRVQVHELLSLYKAGEMDIAKK 206

Query: 166 -------------------------NVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISL 200
                                    NVDG+  L H  GCG        +  +  +     
Sbjct: 207 MQPFVDESQNQTLNSARHQANRPFKNVDGIKFLTHEMGCGGTRQDSGYLCSL--LAGFIN 264

Query: 201 NPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQ 260
           NPN  G   V+ LGC+ LQ + +       +  P     ++ L +++     +++ + ++
Sbjct: 265 NPNVAG-ATVLSLGCQHLQTDMISAEI--KRQNPKFDKPLL-LFEQQAGTEYALMSEAVK 320

Query: 261 IAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFS 320
                L  +N+ +R+  P S L VG++CGGSD FSG++ANPA+G  SD+LV  G   + +
Sbjct: 321 QTFLGLVDINKLERQPAPLSALTVGLKCGGSDGFSGISANPALGQLSDILVTLGGKTVLA 380

Query: 321 EVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVV 380
           E  E+      L  R  + +  ++ +  M  Y        +    NPSPGN K GL    
Sbjct: 381 EFPELNGVEQELINRTDDTDKAQKFITLMGDYSAQAEAVGSGFDMNPSPGNIKDGLITDA 440

Query: 381 EKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGR 440
            K+ G+  K G + + +VL   +  T  GL    TP +D    T    SG  V +FTTG 
Sbjct: 441 IKSAGAAKKGGTAPVADVLDYAEPATTPGLNLLCTPGNDVEATTGMAGSGTNVILFTTGL 500

Query: 441 GTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGK 500
           GTP G    PV+K++T T L NR  D++D ++G I  GE++IE+    +  +I+ +ASG+
Sbjct: 501 GTPTGNPVCPVVKVSTNTVLKNRMPDVIDFDSGPIIDGEQSIEQNANAMLEYIIKLASGE 560

Query: 501 KKTFSDQWGLHNQLAVFNPA 520
             T +++ G  +    +   
Sbjct: 561 VITQAERLG-QDDFIPWKRG 579


>UniRef50_B0T3J7 Altronate dehydratase n=15 Tax=Bacteria RepID=B0T3J7_CAUSK
          Length = 514

 Score =  532 bits (1370), Expect = e-149,   Method: Composition-based stats.
 Identities = 156/504 (30%), Positives = 247/504 (49%), Gaps = 20/504 (3%)

Query: 18  VHDTDNVAIIVNDNGLKAGTRFP-DGLELIEHIPQGHKVALLDIPANGEIIRYGEVIGYA 76
           V   D+VA  + D             +     IP+GHK+A+       ++++YG  IG A
Sbjct: 27  VDPRDHVATALRDLLAGETLDLHGQTIVASTDIPKGHKIAVRAARLGEDLLKYGWPIGRA 86

Query: 77  VRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVGTKNLL 136
              I  G  +    V    +   H        PEP       TF GYR  +G VGT+N +
Sbjct: 87  TADIAVGDHVHVHNVETRLSGVEH-FTYTAGHPEPRQAPPLATFLGYRRKNGRVGTRNEI 145

Query: 137 GITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIH 196
            +  +V CVA     + +        +   +DGV    H +GC    +        + I 
Sbjct: 146 WVLCTVGCVANTARRIAEKANARFAGR---IDGVFAFPHPFGCSQLGDDLTHTR--KLIA 200

Query: 197 NISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVE 256
            ++ +PN GG V+++GLGCE  Q + LL     +    + S +   ++DE   G  + +E
Sbjct: 201 GLAAHPNAGG-VLILGLGCENNQLKALLESAPGLDPERLRSFTTQMVEDELEDGLDA-IE 258

Query: 257 DILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGAT 316
            +++IAER        +RE  P S+LV+G++CGGSD FSGVTANP VG  +D +   G T
Sbjct: 259 ALVEIAER-------DRREPMPLSDLVIGLKCGGSDGFSGVTANPLVGRIADKVSNAGGT 311

Query: 317 VMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGL 376
            + +E+ EV  A  +L  RA   +V  + +  ++ +  Y          NPSPGN  GG+
Sbjct: 312 PVLTEIPEVFGAEGVLLARAATRQVFDQAVGVIDDFKRYFIDNHQPIYENPSPGNIAGGI 371

Query: 377 ANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVF 436
             + EK+LG++ K G+S +VEVL  G++    GL     P +D V  T   A+G TV +F
Sbjct: 372 TTLEEKSLGAVQKGGRSMLVEVLRYGEQVGSHGLTLLEAPGNDAVSSTALTAAGATVILF 431

Query: 437 TTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDV 496
           TTGRGTP G    P +K+A+ + LA R    +D +AG + +G +T++     L   ++  
Sbjct: 432 TTGRGTPLGFP-APTLKIASNSALAARKPGWIDFDAGVVLSG-QTMDAAADSLMDLVVAT 489

Query: 497 ASGKKKTFSDQWGLHNQLAVFNPA 520
           ASG++ T ++      ++A++   
Sbjct: 490 ASGQQ-TKAE-LNGEREIAIWKTG 511


>UniRef50_C1NB77 Altronate dehydratase n=2 Tax=Enterobacteriaceae RepID=C1NB77_9ESCH
          Length = 533

 Score =  531 bits (1367), Expect = e-149,   Method: Composition-based stats.
 Identities = 147/532 (27%), Positives = 234/532 (43%), Gaps = 39/532 (7%)

Query: 16  IKVHDTDNVAIIVNDNGLKAGTRF---PDGLELIEHIPQGHKVALLDIPANGEIIRYGEV 72
           +++   DN+ + + D  L AG  F    D + L+  +   HK A  DIP +G +  YG  
Sbjct: 7   LRIDSNDNLIVALKD--LHAGESFSWDDDNITLVTDVKAKHKFATQDIPLDGIVSMYGTP 64

Query: 73  IGYAVRAIPRGSWIDESMVVLPEAPPLHTL--PLATKVPEPLPPLEGYTFEGYRNADGSV 130
           +G A R I +G  I    +    AP       P   + P+ +      TF+GY   DG V
Sbjct: 65  VGKATRPIVKGEAITVDNIRHYAAPVTLEDVEPYHWQAPD-VSEWSTRTFKGYVRDDGRV 123

Query: 131 GTKNLLGITTSVHCVA--------------GVVDYVVKIIERDLLPK----------YPN 166
           GT +   +   V C                G  +  +K    +L             +P+
Sbjct: 124 GTASYWLVFPLVFCENRNVSKLTNALNDALGYTNNSLKKFALNLTSGSDELIETARMFPH 183

Query: 167 VDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTG 226
           ++GV  +    GCG A +    +     +   + +PN  G + V  LGCEK Q +     
Sbjct: 184 IEGVRCITVTSGCGGATSDCETMCD--VLAAYADHPNVIG-MTVFSLGCEKAQQKMFKDA 240

Query: 227 TDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGM 286
               +  P      +    ++    + M++  LQ     ++ +   +R   P S L VGM
Sbjct: 241 LA--RRNPEFDKPALYFLQQEWDSEERMMQTALQQTFEAMKAVKPTERVEVPLSCLKVGM 298

Query: 287 QCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLL 346
           +CGGSD FSG++ NPA+G  SD L   G     +E  E+  A   +  R +N E  K+ L
Sbjct: 299 KCGGSDGFSGISGNPAMGLVSDWLTTLGGASGLAEFPELCGAEGDMVKRCINLEDKKKFL 358

Query: 347 EEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPT 406
             M+ Y+   N   T  + NPS GN   GL     K+ G+  K G++ IV V    +   
Sbjct: 359 NLMQGYEKTANFFDTTIADNPSFGNIADGLITDAIKSTGAAKKGGRAPIVSVCDYAEPMP 418

Query: 407 KRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFD 466
             GL    TP +D    T  VA+G  V +F+TG GTP G   VPV+K++T + +A R  D
Sbjct: 419 DSGLSLVCTPGNDVDAVTGLVAAGCNVVIFSTGLGTPTGNPIVPVLKISTNSTIARRLSD 478

Query: 467 LMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFN 518
           ++D + G +  G   +E+V  +LF  +++ AS      +D+    +   ++ 
Sbjct: 479 MIDFDCGPVIDG-TPLEDVSRELFEKVIETASKDYVVKADKLEQFD-FMLWK 528


>UniRef50_C4STJ6 Altronate dehydratase n=1 Tax=Yersinia frederiksenii ATCC 33641
           RepID=C4STJ6_YERFR
          Length = 529

 Score =  530 bits (1365), Expect = e-149,   Method: Composition-based stats.
 Identities = 141/530 (26%), Positives = 232/530 (43%), Gaps = 37/530 (6%)

Query: 16  IKVHDTDNVAIIVNDNGLKAGTRF---PDGLELIEHIPQGHKVALLDIPANGEIIRYGEV 72
           +K+ ++DN+ + + +  L+ G       D   L+  +   HK ++ DI   G +  YG  
Sbjct: 5   LKIDESDNLIVALKN--LQKGETVCWGDDHFTLMTDVKAKHKFSVEDIAIGGIVSMYGTP 62

Query: 73  IGYAVRAIPRGSWIDESMVVLPEAP-PLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVG 131
           +G A + I +G  +    +    AP  L+      + P+ +      TF+GY  +DG VG
Sbjct: 63  VGKATKPIAKGEAVTVDNIKHYAAPVQLNDEQYNWQAPD-ISSYIDRTFKGYLRSDGRVG 121

Query: 132 TKNLLGITTSVHCVA--------------GVVDYVVKIIERDLLPK---------YPNVD 168
           T N   +   V C                G  D+ +     +L             P+++
Sbjct: 122 TANYWLVFPLVFCENRNVTKLTDALNDALGYSDHSLTRFAMNLAGGDAPQVKEKLLPHIE 181

Query: 169 GVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTD 228
           GV  +    GCG A +    +     +   + +PN  G + V  LGCEK Q         
Sbjct: 182 GVRSITVSSGCGGAASDSMTMC--EVLAAYADHPNVIG-ITVFSLGCEKAQVIDFKDALK 238

Query: 229 DVQAIPVESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQC 288
                P  S   +  + ++    + M++  L+     + ++    R   P S L +G++C
Sbjct: 239 KCN--PQFSKPTLYFKQQEWENEEQMMQSALKETFACMNEVQPTPRVDVPLSHLKLGVKC 296

Query: 289 GGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEE 348
           G SD FSG++ NPA+G  SD +V  G     +E  E+  A   +  R  + E   + L  
Sbjct: 297 GASDGFSGISGNPAMGLVSDWVVTLGGASALAEFPELCGAEGDMVKRCRHPEDKSKFLSL 356

Query: 349 MEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKR 408
           M  Y+   N   T  + NPSPGN   GL     K+ G+  K G++ I  V    +     
Sbjct: 357 MAGYEKTANFFNTSIADNPSPGNIADGLITDAIKSTGAAKKGGRAPISAVCDYAEPMPDT 416

Query: 409 GLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLM 468
           GL    TP +D V  T  VA+G  V +F+TG GTP G   VPV+K++T TE+ANR  D++
Sbjct: 417 GLSLVCTPGNDVVAVTGLVAAGCNVVIFSTGLGTPTGNPIVPVLKISTNTEIANRLKDII 476

Query: 469 DINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFN 518
           D + G +  G   + +V   LF  +++ AS      SD+   ++   ++ 
Sbjct: 477 DFDCGPVIEG-TPLSDVSQALFERVIETASRDYVVKSDRLEQYD-FLLWK 524


>UniRef50_UPI0001C34772 Altronate dehydratase n=1 Tax=Providencia rettgeri DSM 1131
           RepID=UPI0001C34772
          Length = 531

 Score =  529 bits (1362), Expect = e-148,   Method: Composition-based stats.
 Identities = 145/532 (27%), Positives = 237/532 (44%), Gaps = 39/532 (7%)

Query: 16  IKVHDTDNVAIIVNDNGLKAGTRFPDG---LELIEHIPQGHKVALLDIPANGEIIRYGEV 72
           +K+ ++DN+ + + D  L+AG  +  G   + L+  +   HK A+  IP +G +  YG  
Sbjct: 5   LKIDESDNLIVALKD--LQAGDIYHWGSEEVTLVTDVKAKHKFAMEAIPVDGIVSMYGTA 62

Query: 73  IGYAVRAIPRGSWIDESMVVLPEAPP--LHTLPLATKVPEPLPPLEGYTFEGYRNADGSV 130
           +G A + I +G  I    +    AP       P     P+ +   +G TF+GY   DG V
Sbjct: 63  VGKATKPIAKGEVITVDNIRHYAAPVSLEQDAPYEWNAPD-VSAYQGRTFKGYIREDGRV 121

Query: 131 GTKNLLGITTSVHCVA--------------GVVDYVVKIIERDLLPK----------YPN 166
           GT N   I   V C                G  +  +K    DL             +P+
Sbjct: 122 GTANYWLIFPLVFCENRNVTKLTDALNEALGYTNNSLKNFALDLTAGEQREGAKPKLFPH 181

Query: 167 VDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTG 226
           ++GV  +    GCG A +    +     +   + +PN  G + V  LGCEK Q +     
Sbjct: 182 IEGVRCITVTSGCGGATSDSKTMCD--VLAAYADHPNVIG-ITVFSLGCEKAQRKMFKES 238

Query: 227 TDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGM 286
                +    +   +  + ++    + M++  L+     ++ +  + R   P   L +G+
Sbjct: 239 LAARNSN--FNKPALYFRQQEWNSEEEMMQTALKQTYECMKAVEPQSRVDVPLFHLKLGV 296

Query: 287 QCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLL 346
           +CG SD FSG++ NPA+G  SD LV  G     +E  E+  A   +  R V+ E  ++ L
Sbjct: 297 KCGASDGFSGISGNPAMGLVSDWLVTLGGASGLAEFPELCGAEGDMVKRCVSFEDKRKFL 356

Query: 347 EEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPT 406
           + ME Y+   N   T  + NPSPGN   GL     K+ G+  K G S I  V    +   
Sbjct: 357 DLMERYEKTANFFNTTIADNPSPGNIADGLITDAIKSTGAAKKGGTSPISAVCDYAEPMP 416

Query: 407 KRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFD 466
             GL    TP +D    T  VA+G  V +F+TG GTP G   VPV+K++T + +A R  D
Sbjct: 417 DSGLSLVCTPGNDVDAVTGLVAAGCNVVIFSTGLGTPTGNPIVPVLKISTNSAIAERLSD 476

Query: 467 LMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFN 518
           ++D + G I  G   +  +   LF  +++ ASG  +  +D+    +   ++ 
Sbjct: 477 IIDYDCGPIIDG-VPLPTISKGLFERVIETASGDYQVQADRLEQFD-FLLWK 526


>UniRef50_A0M231 Altronate hydrolase n=9 Tax=Bacteria RepID=A0M231_GRAFK
          Length = 553

 Score =  524 bits (1350), Expect = e-147,   Method: Composition-based stats.
 Identities = 160/553 (28%), Positives = 234/553 (42%), Gaps = 57/553 (10%)

Query: 15  YIKVHDTDNVAIIVNDNGLK-----AGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRY 69
           Y ++   DN+ + + D         AG  FP    L E I Q HK AL D     EII Y
Sbjct: 8   YSQIDTRDNIIVAIQDLPKSTIVNIAGKDFP----LEEAIKQKHKFALYDFQIGDEIIMY 63

Query: 70  GEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGS 129
           G ++G A++ I RG+ I    +    A               +      TF+GY  ADGS
Sbjct: 64  GVLVGEAIQPIKRGAAITTKNIKHASAEFNSEQSKYKWTAPDISKYTERTFKGYHRADGS 123

Query: 130 VGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPK-------------------------- 163
           VGT+N   +   V C    +D V   +   L  +                          
Sbjct: 124 VGTRNYWLVIPLVFCENRNIDVVQDALMEALGYQTNKDYSVDTPKLIEKYKNGASPEELM 183

Query: 164 ----------------YPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGE 207
                           +PNVDG+  L H  GCG            R +     N N  G 
Sbjct: 184 ETSIVHTTEELTKNRLFPNVDGIKFLKHDGGCGGIRQDSET--LCRLLAGYITNSNVAG- 240

Query: 208 VMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQIAERHLQ 267
             ++ LGC+  Q + L     +          +  L+ ++    +  +E  ++     L 
Sbjct: 241 ATILSLGCQNAQMDMLQNAIAEKDKN--FQKPVYYLEQQQIGNERKFIETAVKKTFIGLS 298

Query: 268 KLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRD 327
           + N+  R+    ++LV+G++CGGSD FSG++ N A+GYASDLL   G + + SE  E+  
Sbjct: 299 QTNKIDRKPAALNKLVLGLECGGSDGFSGISCNSALGYASDLLTALGGSPVLSEFPELNG 358

Query: 328 AIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSI 387
               L  R   +E  ++    M  Y        +    NPSPGN K GL     K+ G+ 
Sbjct: 359 VEQELINRCNEKEDAEKFANIMNRYSQRAKDVGSGFENNPSPGNIKDGLITDAMKSAGAA 418

Query: 388 AKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLM 447
            K G S +  VL   ++    GL    TP +D    T    SG  + VFTTG GTP G  
Sbjct: 419 KKGGTSPVTSVLDYTEKVKTPGLNLLCTPGNDVESTTGLAGSGCNMIVFTTGLGTPTGNP 478

Query: 448 AVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQ 507
             PV+KM++ T L  R  D++DINAGT+ TGE+TI+ +G K+   I+ VASG+K+  +  
Sbjct: 479 VAPVLKMSSNTALFERMNDIIDINAGTVITGEDTIQSMGEKILDEIILVASGEKEAKA-V 537

Query: 508 WGLHNQLAVFNPA 520
               N    +   
Sbjct: 538 LQNQNDFIPWKRG 550


>UniRef50_C6J327 Altronate dehydratase n=1 Tax=Paenibacillus sp. oral taxon 786 str.
           D14 RepID=C6J327_9BACL
          Length = 494

 Score =  517 bits (1333), Expect = e-145,   Method: Composition-based stats.
 Identities = 149/467 (31%), Positives = 235/467 (50%), Gaps = 19/467 (4%)

Query: 14  FYIKVHDTDNVAIIVNDNGLKAGTRF---PDGLELIEHIPQGHKVALLDIPANGEIIRYG 70
             +K++  DNV + +    + AG       + +   + IPQGHK+AL  IPA   + +YG
Sbjct: 42  RLMKMNPRDNVGVALQ--PITAGEELQLNEESVRAAQDIPQGHKIALTAIPAGSSVTKYG 99

Query: 71  EVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSV 130
             IG+ V AI  G W+    +                +   + P   +TF+GYR A+G  
Sbjct: 100 YSIGHVVTAIAPGEWVHTHNIR-TNLAGEEQYVYQPNLHPVIYPKRSFTFQGYRRANGKT 158

Query: 131 GTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVV 190
           G +N L I  +V CV G+ + +++  + +     P  D +  L+H YGC         ++
Sbjct: 159 GIRNDLYIVPTVGCVNGIAEQMIRAFKAEHPDLGP-FDNITVLSHPYGCSQL--GEDHLM 215

Query: 191 PIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVG 250
               + +  L+PN GG V+V GLGCE                  V+      ++DE    
Sbjct: 216 TRSILADTVLHPNAGG-VLVFGLGCENNVVSEFRERLGHYDEQRVKFLVAQEVEDE---- 270

Query: 251 FQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLL 310
               +E  L + E  ++     +RE  P SE+ VG++CGGSD+FSG+TANP +G  SD L
Sbjct: 271 ----LEAGLALLEELVEAARNDRREPVPLSEMNVGLKCGGSDSFSGITANPLLGAFSDFL 326

Query: 311 VRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPG 370
           +  G + + +EV E+  A  +L  RA ++EV ++++  +  +  Y          NPSPG
Sbjct: 327 ISQGGSTILTEVPEMFGAEKMLMARAESQEVFEQIVVLINDFKQYFLFYGEPVYENPSPG 386

Query: 371 NKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASG 430
           NK GG++ + +K+LG   K+G + +V+VL  G++  K+GL    TP +D V  +   A+ 
Sbjct: 387 NKAGGISTLEDKSLGCTQKAGTAPVVDVLKYGEKLRKKGLSLLQTPGNDLVASSALAAAD 446

Query: 431 ITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIAT 477
             + +FTTGRGTP+G   VP +K+AT  EL  R    MD NAG +  
Sbjct: 447 CQLVLFTTGRGTPFGS-FVPTVKVATNNELFARKQHWMDFNAGVLLD 492


>UniRef50_C7PV23 Altronate dehydratase n=13 Tax=Bacteria RepID=C7PV23_CHIPD
          Length = 554

 Score =  517 bits (1331), Expect = e-145,   Method: Composition-based stats.
 Identities = 164/554 (29%), Positives = 238/554 (42%), Gaps = 58/554 (10%)

Query: 15  YIKVHDTDNVAIIVNDNGLKAGTRFPDG---LELIEHIPQGHKVALLDIPANGEIIRYGE 71
            +KVH  DNV + + D  LK G    +      L E +P  HK     +     I  YG 
Sbjct: 8   VLKVHPQDNVVVALTD--LKKGESVQENGRVYTLAEDVPAKHKFTETILHPGDAITMYGV 65

Query: 72  VIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPP---LEGYTFEGYRNADG 128
           ++G A   +P G+ I    V    A     L    K    +P     +  TF GY  ADG
Sbjct: 66  LVGKAKELLPAGAKIAVGNVQH--ASSDFQLAATRKTAWHIPDISKWQDRTFMGYHRADG 123

Query: 129 SVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYP----------------------- 165
           SVGT N   +   V C    V+ + + +  +L    P                       
Sbjct: 124 SVGTGNYWLVIPMVFCENRNVEVLRETLVEELGYGRPKKYAAFARQLAQQYQQGADASAI 183

Query: 166 -------------------NVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGG 206
                              NVDG+  L H  GCG        +  +  +     + N  G
Sbjct: 184 LETVYTEDPAQQGQQRLFENVDGIKFLTHEGGCGGIRQDAQTLCGL--LAGYITHANVAG 241

Query: 207 EVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQIAERHL 266
              V+ LGC+  Q   L          P  S  +  L  ++    Q+++   ++     L
Sbjct: 242 -ATVLSLGCQNAQITMLEEEIRKRS--PDFSKPLFILDQQQTGTEQALITAAVRQTMAGL 298

Query: 267 QKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVR 326
            + N+  R   P  +L +G++CGGSD FSG++ANPA+GY SDLLV  G +V+ SE  E+ 
Sbjct: 299 IEANKITRTPAPLYKLCIGLECGGSDGFSGISANPAIGYTSDLLVALGGSVILSEFPELC 358

Query: 327 DAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGS 386
                ++ R VN     R +E M  Y        +    NPSPGN K GL     K+ G+
Sbjct: 359 GVEQEMSDRCVNTTDALRFIELMRTYQRRAEEAGSGFDMNPSPGNIKDGLITDAIKSAGA 418

Query: 387 IAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGL 446
             K G S +  VL   Q+ +  GL    TP +D    T +V +G T+ +FTTG GTP G 
Sbjct: 419 AKKGGTSPVAAVLDYPQKVSLPGLNLLCTPGNDVESTTAEVGAGATIVLFTTGLGTPTGN 478

Query: 447 MAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSD 506
              PVIK+++ T+L  R  D++DIN GTI  GEE+I E G ++ ++++DVASG  K  S 
Sbjct: 479 PVTPVIKLSSNTKLYQRMPDIIDINTGTIIDGEESIPEAGERILNYVIDVASGITKARS- 537

Query: 507 QWGLHNQLAVFNPA 520
                +    +   
Sbjct: 538 VINGQDDFIPWKRG 551


>UniRef50_B5FMP6 Hydrolase, UxaA family n=75 Tax=cellular organisms
           RepID=B5FMP6_SALDC
          Length = 408

 Score =  476 bits (1224), Expect = e-132,   Method: Composition-based stats.
 Identities = 133/407 (32%), Positives = 205/407 (50%), Gaps = 23/407 (5%)

Query: 116 EGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNH 175
              TF G+R  DG  G +N + I  +  C   V   + +            V G   +N+
Sbjct: 22  SNETFLGFRRPDGRFGIRNYVLILPTSVCANKVARDIAR-----------QVKGATWVNN 70

Query: 176 LYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPV 235
            +GC        A +  +T+ N++ NPN G  V V+GLGCE  +P R+            
Sbjct: 71  DFGCCQVAGD--ARLTEKTLINVANNPNVGAIV-VVGLGCEGAEPLRIAEEITA------ 121

Query: 236 ESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFS 295
                  +  ++  G        + +A  + Q+L+ ++ +  P SEL++ M+CGGSD  S
Sbjct: 122 FGKPTSCITIQEEGGTLKCQARGISLARDYAQQLSMQKPQQAPVSELLLAMECGGSDTTS 181

Query: 296 GVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNY 355
           G+ +NP+ G ASD L+RCG + + SE TE   A H++  RAV  EVG++L++ +   +  
Sbjct: 182 GLASNPSCGVASDKLIRCGGSSILSETTEFIGAEHVMAKRAVTPEVGQQLIDLVVGCEAR 241

Query: 356 LNM-GKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAA 414
               G+  R   P+PGN KGGL  + EK+LG + K+G + +  VL     PT  GL    
Sbjct: 242 AKALGEDIRGGQPTPGNIKGGLTTIEEKSLGCMHKAGHAPLQGVLEYADSPTHPGLWIMD 301

Query: 415 TPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGT 474
           TP  D    +  VA G  + +FTTGRGTP G    PVIK+           D +DI+   
Sbjct: 302 TPGQDIESISGMVAGGAQIVIFTTGRGTPAGNPIAPVIKITGNKATWEMMQDNIDIDVSA 361

Query: 475 IATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAP 521
           I +GE +I ++G +++  IL VA+GK  T S+  G HN+ +++  AP
Sbjct: 362 IMSGEASITQMGEEIYQEILRVANGK-TTKSEDLG-HNEFSIYKIAP 406


>UniRef50_B0K1I9 Altronate dehydratase n=10 Tax=Firmicutes RepID=B0K1I9_THEPX
          Length = 389

 Score =  459 bits (1180), Expect = e-127,   Method: Composition-based stats.
 Identities = 134/400 (33%), Positives = 209/400 (52%), Gaps = 22/400 (5%)

Query: 120 FEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGC 179
            + Y+  DG  G +N + I  SV C       + +            V G   + +  GC
Sbjct: 3   IKAYKRPDGKYGIRNKVLILPSVGCANETARLISE-----------QVQGTTYITNPKGC 51

Query: 180 GVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESAS 239
           G      +  +  RT+  ++LNPN  G + ++GLGCE +Q   L          PVE   
Sbjct: 52  GQI--GSSVELMHRTLIGLTLNPNVYGTI-IVGLGCETIQAYDLYEEVKKRSNKPVE--- 105

Query: 240 IVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTA 299
              +  ++  G    ++  +++A + ++++++ +RE    S + +   CGGSDA SG+ A
Sbjct: 106 --VISIQREGGTLKTIQKGIKLARKMVEEMSKIEREEVDISNITLATNCGGSDATSGIAA 163

Query: 300 NPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYD-NYLNM 358
           NP +GY SD+L++ GATV   E TE   A H+L  RA NE+V   LL  ++  +  ++ +
Sbjct: 164 NPTLGYCSDILIKEGATVFLGETTEFIGAEHILARRAKNEKVRNNLLTIVKNLENEFIRL 223

Query: 359 GKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPAS 418
           G   R ANPSPGN KGGL+ + EK+LGSI K G S I EV+  G+ P ++GLI   TP  
Sbjct: 224 GIDVRGANPSPGNIKGGLSTLEEKSLGSIMKGGTSIINEVVRYGEIPKEKGLIIMDTPGY 283

Query: 419 DFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATG 478
           D    T  VA G  + VFTTGRGTP G   +P+IK+    +      D +D++   I  G
Sbjct: 284 DIESVTGMVAGGAQICVFTTGRGTPIGNPIIPLIKITGNKQTYENMSDNIDLDVSDIIEG 343

Query: 479 EETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFN 518
           ++ I+E G  L   I+DV +GK  T ++ +G  ++  ++ 
Sbjct: 344 KKDIKECGEMLLQEIIDVCNGK-LTKAEIYGF-SETCIYR 381


>UniRef50_Q5WIY9 Altronate hydrolase C-terminus n=5 Tax=Firmicutes
           RepID=Q5WIY9_BACSK
          Length = 388

 Score =  454 bits (1168), Expect = e-126,   Method: Composition-based stats.
 Identities = 149/403 (36%), Positives = 215/403 (53%), Gaps = 22/403 (5%)

Query: 120 FEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGC 179
             G+   DG VG +N + I  ++ C       V K+           VDG V + H +GC
Sbjct: 5   ITGFSRQDGQVGIRNHVLILPTIVCATQAAQNVTKL-----------VDGTVSVIHQHGC 53

Query: 180 GVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESAS 239
               +        RT   + LN N  G V+V+GLGCE  Q + +          PVE  S
Sbjct: 54  AQVGSDYEQT--FRTYVGMGLNANVYG-VVVMGLGCETHQGKSVAEEIAKKSNKPVELVS 110

Query: 240 IVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTA 299
           I     + + G      +  +IA + +Q  +  +RE    S+L+VG +CGGSDA SG++A
Sbjct: 111 I-----QDYGGTLQATCEAARIATKMVQDASMLEREPIAFSDLIVGTECGGSDACSGLSA 165

Query: 300 NPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYL-NM 358
           NPAVGY SD +   G T + +E TE+  A HLL  RA N+ V KR+ E +E  +N    M
Sbjct: 166 NPAVGYVSDAIADYGGTSILAETTELIGAEHLLAGRAANDHVAKRVYEVIEAMENRAYQM 225

Query: 359 GKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPAS 418
           G   R+ NPSPGNK+GGL  + EK+LG+ AK+G   + E++   +RPTK+GL++  TP  
Sbjct: 226 GVDIRTGNPSPGNKQGGLTTLEEKSLGAAAKAGTRTLHEIVDYAKRPTKKGLVWMDTPGH 285

Query: 419 DFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATG 478
           D    T   A G  + +FT+GRGTP G    PVIK+AT T +  +  + +D NAGTI  G
Sbjct: 286 DIEQLTGMTAGGAQLVLFTSGRGTPTGSPIAPVIKIATNTAMFEKMNENIDFNAGTIIEG 345

Query: 479 EETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAP 521
           +E+IE  G +L   +  VASGK+ T ++    H+   ++   P
Sbjct: 346 KESIESTGERLLAEVAAVASGKR-TKAEILKQHD-FGIWRIGP 386


>UniRef50_Q6L323 Altronate hydrolase n=1 Tax=Picrophilus torridus RepID=Q6L323_PICTO
          Length = 393

 Score =  446 bits (1147), Expect = e-123,   Method: Composition-based stats.
 Identities = 127/405 (31%), Positives = 204/405 (50%), Gaps = 21/405 (5%)

Query: 120 FEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDG-VVGLNHLYG 178
           F GY  ++G  GT+N + I  +V C     ++ V+ I R+ L  Y N DG +  LN+ YG
Sbjct: 5   FLGYERSNG-FGTRNHILIIPTVTCS----EFTVRRIARESLKYYNNPDGSIKVLNNPYG 59

Query: 179 CGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESA 238
           CG            RT+ N+ +NPN  G V+V+ LGCE +   ++            +  
Sbjct: 60  CGQT--GEDLEQTTRTLINMGINPNVSG-VLVLSLGCESVDYNKVADEIS-------KYK 109

Query: 239 SIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVT 298
            +  L+ + + G    VE  ++  +       + +R       +  G++CGGSD  SG+ 
Sbjct: 110 PVNFLRIQDYGGL-KTVETGIEKIKDLAANAIKEKRNETDLKNITAGLECGGSDFTSGLA 168

Query: 299 ANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYL-- 356
           +NP VG  SD ++  G + + SEV E   A HL   RAVNE+V  ++ + +  ++  L  
Sbjct: 169 SNPVVGKVSDWIINNGGSTIISEVPEFIGAEHLYAARAVNEDVRAQIFKTVYAFEKKLKE 228

Query: 357 NMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATP 416
                 R   P+PGN +GGL  + EK+LG++ KSG + +  VL  G+R +K G     TP
Sbjct: 229 EARVDFRKGQPTPGNMEGGLTTIEEKSLGAVKKSGSAKVSGVLKYGERLSKPGHYLMNTP 288

Query: 417 ASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIA 476
             D    + +VA G  + +FTTGRGTP G +  PVIK+    E   +  D++D +A  I 
Sbjct: 289 GYDVESVSGEVAGGANIVMFTTGRGTPTGNIISPVIKITANEETFKKMEDIIDFDASPIM 348

Query: 477 TGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAP 521
            G+ETIE    +L   +++ A+G + T ++     +  A++   P
Sbjct: 349 RGDETIESASERLKKLLIETANG-RLTKAE-INEQDDFAIYRIGP 391


>UniRef50_Q1AYL8 D-galactarate dehydratase/Altronate hydrolase-like protein n=2
           Tax=Bacteria RepID=Q1AYL8_RUBXD
          Length = 895

 Score =  437 bits (1123), Expect = e-121,   Method: Composition-based stats.
 Identities = 138/527 (26%), Positives = 220/527 (41%), Gaps = 42/527 (7%)

Query: 20  DTDNVAIIVNDNGLKAGTRFPDG---LELIEHIPQGHKVALLDIPANGEIIRYGEVIGYA 76
             DNVAI      L+AGTR   G     L   + +GH+ A+  I     ++ +G   G+A
Sbjct: 17  PRDNVAIATRR--LEAGTRVRCGGSSFSLSHAVLEGHRFAVSRIGEGEALLSWGLPFGWA 74

Query: 77  VRAIPRGSWIDESMVV-----------LPEAPPLHTLPL------------ATKVPEPLP 113
           +R I  G ++  + ++           LP  P     PL              +VP    
Sbjct: 75  LREIRPGEYVCNARILRVLRERRVDLDLPGEPNFRDDPLRPYVLDERNFGPGEQVPRHER 134

Query: 114 PLEGYTFEGY-RNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVG 172
           P    TF GY R A    GT+N + +             + + +   L    P +DG+V 
Sbjct: 135 P---GTFMGYGRGAARGAGTRNHIVVLGLTSRTGPYARALERRLA-GLAAGVPGLDGIVA 190

Query: 173 LNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQA 232
           + H  G G         + +RT+    ++PN  G V+ +  G   L    L     + + 
Sbjct: 191 VAHTEG-GEDRPPNNLGLLLRTLAGFMVHPN-AGAVLAVDDGRGALTGGALRRYMKE-RG 247

Query: 233 IPVESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSD 292
            P+       +       F   +    +     L +    +R   P S L + +QCGGSD
Sbjct: 248 YPLREVPHRFMTLRGS--FAGELRRGERAVRGWLGEAGSARRSPQPLSRLRLALQCGGSD 305

Query: 293 AFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWY 352
           AFSGV+ANP V + +  L+R G +   +E  E+  A   +     +    +R L+ +E +
Sbjct: 306 AFSGVSANPLVAWVARELLRHGGSANLAETDELIGAERYVLENVRDLATARRFLQTVERF 365

Query: 353 DNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVE-VLSPGQRPTKRGLI 411
              +         NPS GN   GL N+  K++G+  K      ++ V+    R    G  
Sbjct: 366 RELVGRHGHTAEGNPSGGNNYRGLYNIAIKSIGAARKKDPGVRLDYVIPYAGRMDAPGYY 425

Query: 412 YAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDIN 471
           +  +P +D      QVASG  V  FTTG G+      VP IK+ + T       D MD+N
Sbjct: 426 FMDSPGNDLESVAGQVASGANVIFFTTGNGSITNFPFVPTIKVVSTTGRYRLLADEMDVN 485

Query: 472 AGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFN 518
           AG    G   +EE+G   F   + VASG++ T  ++ G H+Q++++ 
Sbjct: 486 AGAYLDG-TPMEELGRDAFDLAVRVASGER-TAGERAG-HSQVSIWR 529



 Score = 91.6 bits (226), Expect = 7e-17,   Method: Composition-based stats.
 Identities = 77/449 (17%), Positives = 141/449 (31%), Gaps = 92/449 (20%)

Query: 70  GEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLE---GYTFEGYRNA 126
           GE  G++  +I    W +      P    L   P     P PL   E   G++FEG R  
Sbjct: 517 GERAGHSQVSI----WRNWRQTSRPSPAALREPPEPDGRPLPLGEREEAGGFSFEGVRKG 572

Query: 127 DGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAP 186
           +G    + +  I  +  C   +   +   +   L      +   V L H  GCGV+    
Sbjct: 573 EGYAADR-VGLIMPTSLCAGQIALIIAGRLN-GLGVGEGKLSRFVALPHTEGCGVSG-GH 629

Query: 187 AAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDE 246
           +  +  RT+     +P+ G   +++  GCEK   +       +    P +         +
Sbjct: 630 SERLYARTVLGYLSHPSVGA-ALLLEHGCEKTHNDYFRARLAERGLDPGDFG---WASIQ 685

Query: 247 KHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGG--SDAFSGVTANPAVG 304
              G + +V  +       L+ + + +RE      L VG+   G   +  +G     A+ 
Sbjct: 686 LDGGIERVVRRVEGWFGEALEGMGEMEREPAGPEHLRVGLHAEGPLPEGTAG-----ALA 740

Query: 305 YASDLLVRCGATVMFSE-VTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDR 363
             +  +   G TV+  E    +      +  RA                           
Sbjct: 741 QLALRVAASGGTVVIPERSPALEGLRGRVPLRA--------------------------- 773

Query: 364 SANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCG 423
                          +           G+      L   + PT                 
Sbjct: 774 --------------TLA---------YGQRPAAPGLHVMEAPT----------GDWMEIA 800

Query: 424 TQQVASGITVQV-FTTGRGTPY-GLMAVPVIKMATRTELANRWFDLMDINAGTIATGEET 481
           T   A+G+ V +    GR  P      VP+++ ++  E   R  + +D+       GE +
Sbjct: 801 TGLGAAGVEVMLAHVAGR--PLRAHRLVPLLQASSDAETLYRCGEDLDV----ALRGEPS 854

Query: 482 IEEVGWKLFHFILDVASGKKKTFSDQWGL 510
                 +    +L+ ASG++     + G 
Sbjct: 855 GWRAALE--RAVLEAASGRRFPRLARQGY 881


>UniRef50_D1Y174 D-galactarate dehydratase (GalcD) n=3 Tax=Bacteria
           RepID=D1Y174_9BACT
          Length = 386

 Score =  432 bits (1111), Expect = e-119,   Method: Composition-based stats.
 Identities = 131/394 (33%), Positives = 192/394 (48%), Gaps = 21/394 (5%)

Query: 120 FEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGC 179
           F GY+  +G  G +N + I  +  C +     V   +                +N ++  
Sbjct: 3   FWGYKRQEGRAGIRNHVLILPTCACGSESARIVASEVRG-------------AVNIIFNT 49

Query: 180 GVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESAS 239
           G +  A    +  + +   + NPN  G V++IGLGCE +   +L      +   PV    
Sbjct: 50  GCSDVAANTAMSQKVLMGFACNPNVYG-VVIIGLGCETVGHAQLREKIRGMTGKPV---- 104

Query: 240 IVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTA 299
            VS   ++  G    +E  ++ A         +Q+E C  S L++G++CGGSDA SG+ +
Sbjct: 105 -VSFGIQEEGGTLKTIEKAVRAARDMAAAAAMQQKERCDMSNLLLGIECGGSDATSGIAS 163

Query: 300 NPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMG 359
           NPAVG  SDLLV  GA+ + SE  E   A H++  RA   E+  +++E    Y+ +L   
Sbjct: 164 NPAVGELSDLLVDLGASTIMSESIEWIGAEHVVARRAATPELHNKIIEICRDYEEHLKAA 223

Query: 360 KTD-RSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPAS 418
             D R+  P+PGNK GGL+ + EK+LG I K G   IVEVL+  +RPTK G I   T   
Sbjct: 224 GQDCRAGQPTPGNKAGGLSTLDEKSLGCIRKGGTRPIVEVLAQAERPTKHGAIVMDTAGY 283

Query: 419 DFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATG 478
           D    T  VA G    +FTTGRGTP G   VPV+K+           D MD++   I  G
Sbjct: 284 DISSVTSMVAGGCNAVIFTTGRGTPTGNAIVPVLKVTANARTYRMMDDNMDVDLSGIIKG 343

Query: 479 EETIEEVGWKLFHFILDVASGKKKTFSDQWGLHN 512
             T  E G +L   I DV +GK  T ++ +G  +
Sbjct: 344 TTTYRESGRELLEIIGDVCNGK-MTKAEAYGFSD 376


>UniRef50_C0CW83 Putative uncharacterized protein n=1 Tax=Clostridium asparagiforme
           DSM 15981 RepID=C0CW83_9CLOT
          Length = 387

 Score =  430 bits (1107), Expect = e-119,   Method: Composition-based stats.
 Identities = 124/405 (30%), Positives = 200/405 (49%), Gaps = 23/405 (5%)

Query: 120 FEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGC 179
           F+GY   DG+VG++NL+ +  SV C   V   +V             V G VGL H  GC
Sbjct: 3   FQGYVRPDGTVGSRNLVAVIPSVVCANDVAQAIVA-----------QVQGTVGLYHHQGC 51

Query: 180 GVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESAS 239
                         T+  +   PN G   +V+ LGCE    ERL+               
Sbjct: 52  CQLPPDLDR--VTETLIGLGCGPNVGA-ALVVSLGCEGTDHERLVEEI------ARTGKP 102

Query: 240 IVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTA 299
           +  ++ ++  G    +   +  A R ++ +  +QR     S++V+ ++CG SD  SG+ +
Sbjct: 103 VEIIRIQQLGGVSKAIAAGIDAASRLVRAIAPQQRREADISKVVLAIKCGASDTTSGMAS 162

Query: 300 NPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNM- 358
           N A+GY +D LV  G TV+F E TE   A H+L  RAVN +V  ++ E +   ++     
Sbjct: 163 NCALGYVADKLVDLGGTVVFGETTEFLGAEHILKRRAVNAQVADKIDEIVARMESRAKSL 222

Query: 359 GKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRP-TKRGLIYAATPA 417
           G   R   P+PGN +GGL+++ EK+LG+I KSG   I  V+    R   ++GL    TP 
Sbjct: 223 GCDMRKGQPTPGNIEGGLSSIEEKSLGAIVKSGTRPIQGVMEYTDRVGDRKGLWIKDTPG 282

Query: 418 SDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIAT 477
            +    T    +G  + +F+TGRG P G   +PV+K+           + MDINAG I  
Sbjct: 283 REPEILTGMACTGAQLMMFSTGRGAPQGFPTMPVVKVCGNPITYRNMENDMDINAGLIIE 342

Query: 478 GEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAPV 522
           G+++IE+VG ++F  I++V +G   + ++    ++ + ++   PV
Sbjct: 343 GKKSIEQVGEEVFEKIVEVLNGG-MSKNESLHYYSSIDIYTLGPV 386


>UniRef50_D1Y193 Galactarate dehydratase n=1 Tax=Pyramidobacter piscolens W5455
           RepID=D1Y193_9BACT
          Length = 408

 Score =  426 bits (1096), Expect = e-118,   Method: Composition-based stats.
 Identities = 124/410 (30%), Positives = 202/410 (49%), Gaps = 28/410 (6%)

Query: 116 EGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNH 175
              TF GYR +DG+VG +N L I  SV C    V+ +              + G V + H
Sbjct: 1   MTMTFNGYRRSDGTVGVRNHLAIIPSVFCANRTVERIAA-----------QLPGSVPIRH 49

Query: 176 LYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPV 235
             GC          +  RT+  +  +PN G  V+VIGLGCE+  P  L       +A+  
Sbjct: 50  AVGCSQV--GLDLELTARTLKALGTHPNVGA-VLVIGLGCERFPPREL------EEAVRK 100

Query: 236 ESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFS 295
               +     ++  G  + ++  ++   +    L +++R  CP SEL VG +CGG+DA S
Sbjct: 101 SGRPVACFVIQEEGGTTNTIKHAVEAGRKMFASLAEQRRVPCPLSELFVGTKCGGTDATS 160

Query: 296 GVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNY 355
           G+ ANPAVG   D LV  G + + SE+ E+    H+L  RAV++EV  ++ + +   ++ 
Sbjct: 161 GLAANPAVGEMVDKLVAQGGSAILSEMNELLGTEHILARRAVSKEVADKVYKAIYEIEDV 220

Query: 356 LNMG-----KTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPT--KR 408
           L  G        R+   SPGN  GG++++VEKALG + KSG   IV+V+     P   K+
Sbjct: 221 LRSGIDMRLGAKRNQLISPGNADGGVSSIVEKALGGMHKSGTCPIVDVIDYATPPEKGKK 280

Query: 409 GLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLM 468
           GL      + D    T ++  G  +  FTTGRG+P G    PV+K+    +      ++ 
Sbjct: 281 GLFLMKYESHDGEVTTGEIGCGAQIVAFTTGRGSPTGHPIAPVVKITGNEKTYKAMSEMF 340

Query: 469 DINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFN 518
           D +A  I +  +++E+ G  L   ++ VA G++ T +++ G  + + +  
Sbjct: 341 DFDASGIISRGDSLEDTGRALLDLVIRVADGER-TQAEKTGDDSLMCIAR 389


>UniRef50_A9V9F3 Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9V9F3_MONBE
          Length = 958

 Score =  420 bits (1079), Expect = e-116,   Method: Composition-based stats.
 Identities = 129/508 (25%), Positives = 201/508 (39%), Gaps = 53/508 (10%)

Query: 55  VALLDIPANGEIIRYGEVIGYAVRAIPRGSWIDE-------------------------- 88
           +AL  I    +I  +G   G A+  +  GS++                            
Sbjct: 41  LALDFIAKGTQITSWGLPFGIALMDLAPGSYLCNLKSLATFADRHSKLNLPSEPTFRNAP 100

Query: 89  ---SMVVLPE---APPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVGTKNLLGITTSV 142
                V       APP      A   P PL    G+   G R A    GT+N + I    
Sbjct: 101 FTRHTVAQQNFSPAPPTKRDESAAATPAPLTTFMGFPRGGNRGA----GTRNYVVILGIS 156

Query: 143 HCVAGVVDYVVKII-----ERDLLPKYPNVDGVVGLNHLYGCGVA----INAPAAVVPIR 193
              AG    + +       +   L      DGVV + H  G   A     N       +R
Sbjct: 157 SRAAGFARALERQFTHTLEQARTLQGQATCDGVVAVAHTEGGLDAKLTTDNENNVEKVLR 216

Query: 194 TIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQS 253
            +   +++PN G  V+ +  G E +    +L         P++     +L  +     ++
Sbjct: 217 VLAGFAVHPNVGA-VLFLDHGDEVVTTRHVLEYIRA-HDYPLDDVPYRALSLKNQTMKEA 274

Query: 254 MVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRC 313
           M +   ++ E    +  Q QR       L    QCGGSDAFSG++ANP  G+ +  LV  
Sbjct: 275 MHQ-ATELVEELYLQAQQHQRVAVGVEHLCFAQQCGGSDAFSGISANPLAGWMARELVAQ 333

Query: 314 GATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKK 373
           G + + +E  E+  A   +  R  + +     L+ ++ Y  Y N        NPS GN  
Sbjct: 334 GGSAVLAETDELIGAESYVLQRVRDYDTADHFLQLVDRYYRYTNRRGHSPEGNPSGGNLY 393

Query: 374 GGLANVVEKALGSIAKSGKSAIVE-VLSPGQR--PTKRGLIYAATPASDFVCGTQQVASG 430
            GL N+  K+ G+  K      ++ VL  GQR  P   G  +  +P +D      QVA+G
Sbjct: 394 RGLYNITLKSAGAAMKKLPDVRLDHVLEYGQRLQPEGHGYAFMDSPGNDLESIAGQVAAG 453

Query: 431 ITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLF 490
             + VFTTG G+      VP IK+ T T+      D MD+NAG    GE ++ ++G + +
Sbjct: 454 CNMIVFTTGNGSVTNFPFVPTIKVLTTTKRYQLLSDDMDVNAGRFLDGEVSLSQLGREAY 513

Query: 491 HFILDVASGKKKTFSDQWGLHNQLAVFN 518
              +  ASG   T  +  G H Q+ ++ 
Sbjct: 514 QLFVRAASGTP-TKGELAGHH-QVQIWR 539



 Score = 72.3 bits (176), Expect = 4e-11,   Method: Composition-based stats.
 Identities = 33/184 (17%), Positives = 67/184 (36%), Gaps = 8/184 (4%)

Query: 145 VAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNF 204
              +   +         P +  +   V L H  GCG +     + + +RT+ + + +P  
Sbjct: 637 ADKIARQLNDRKAAQNAPIFAGLSRFVALPHTEGCGHSSGDHES-LVMRTLSSYAAHP-M 694

Query: 205 GGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQIAER 264
            G V+++  GCEK    R      +  ++ ++  +  S+Q     G   +   + Q+ E+
Sbjct: 695 AGAVVMLEHGCEKTHNGRFQQLLSEDPSVSLDRCAFASIQL--DGGLNKVTSRVEQLLEQ 752

Query: 265 HLQKLNQRQ-RETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVT 323
                     R+    S + +G+        S   A   +G     +   G TV+ +   
Sbjct: 753 LELSSTSVPVRQPAAVSHIRIGILATTPLPTSVQAA---LGLVVAAVTLEGGTVVLAGSH 809

Query: 324 EVRD 327
            VR 
Sbjct: 810 VVRG 813


>UniRef50_B8FML6 Altronate dehydratase n=1 Tax=Desulfatibacillum alkenivorans AK-01
           RepID=B8FML6_DESAA
          Length = 386

 Score =  405 bits (1040), Expect = e-111,   Method: Composition-based stats.
 Identities = 130/389 (33%), Positives = 195/389 (50%), Gaps = 23/389 (5%)

Query: 119 TFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYG 178
           +F GY   DGSVG +N + +  S           V             V GVV L H  G
Sbjct: 3   SFMGYGREDGSVGVRNYVAVIPS-----------VACAAPVAAAIARAVPGVVPLLHGMG 51

Query: 179 CGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESA 238
           CG       A +  RT  N+  NPN G  V+++GLGCE      ++       A  +   
Sbjct: 52  CGRG--GSDADMHTRTFQNLCKNPNVGA-VIIVGLGCE------VVNAEGMALAAAMAGR 102

Query: 239 SIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVT 298
               L  +   G +      + IA+  + ++  ++R+  P  +L +G++CGGSDAFSGVT
Sbjct: 103 PHARLMIQAEGGSRKTTAKGIGIAKDFMTQIQVQERKPFPLDKLTLGLECGGSDAFSGVT 162

Query: 299 ANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYD-NYLN 357
           ANPAVG ASD LV  G  V+ +E TE+    H+L  R+ N E+ +++   +   +     
Sbjct: 163 ANPAVGRASDWLVAKGGKVILTETTEMIGTSHILERRSANPEIAEQIKNLISSVEAKTYE 222

Query: 358 MGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPA 417
           +         SPGN  GG++++ EKALG I K G + I +V+   + PT+ GL     P 
Sbjct: 223 VLGPIAKMIMSPGNMDGGMSSIREKALGCIIKGGTTPINQVVDYAEIPTQPGLSIMHGPG 282

Query: 418 SDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIAT 477
            D    T   ASG  V VFTTGRG P G   VPV+K+A+ + +     D MD+NAG I  
Sbjct: 283 YDAESLTGLAASGAQVIVFTTGRGNPIGFPIVPVVKVASTSRMFQSMEDDMDLNAGAILE 342

Query: 478 GEETIEEVGWKLFHFILDVASGKKKTFSD 506
           G ++++++G  +   ILD  +G++ T ++
Sbjct: 343 G-KSLDQMGEDVVQCILDAVNGRR-TKAE 369


>UniRef50_A8RT57 Putative uncharacterized protein n=1 Tax=Clostridium bolteae ATCC
           BAA-613 RepID=A8RT57_9CLOT
          Length = 412

 Score =  404 bits (1039), Expect = e-111,   Method: Composition-based stats.
 Identities = 117/415 (28%), Positives = 184/415 (44%), Gaps = 39/415 (9%)

Query: 116 EGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNH 175
             Y++ GY   +G++G +N + +  +V C + V   +V+      L   P  + VVG + 
Sbjct: 12  REYSWMGYVRKNGAMGIRNKVLVIYTVECASFVAREIVR------LAGDPETE-VVGFS- 63

Query: 176 LYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPV 235
               G   N  A    +R +  +  +PN G  V+ +GLGCE +QPE L     D+     
Sbjct: 64  ----GCTDNEYA----VRLLIALIRHPNVGA-VLTVGLGCEYVQPEWLA----DIAGKEG 110

Query: 236 ESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFS 295
           + A+ + +Q E   G +  +E  L +     ++L   +R+     +L++G +CGGSD  S
Sbjct: 111 KEAAWMFIQQE--GGTRKTIEKGLAVVGLMRERLKDTKRKPMGIRDLIIGAECGGSDYTS 168

Query: 296 GVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNY 355
           G+  N  VG   D L   G T +F E+ E      +L  RA NE   + + +    YD  
Sbjct: 169 GLAGNVVVGRFFDRLTDLGGTAIFEEIVEAIGLKEMLVGRAANERARQEIGDT---YDKA 225

Query: 356 LNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAA- 414
           L   K+ R  + SPGN  GGL+ + EK++G++ KSG   I  VL  G +P   GL     
Sbjct: 226 LEYCKSVRQYSVSPGNFAGGLSTIEEKSMGALIKSGSRPIEGVLKVGVKPPHPGLWLLDS 285

Query: 415 TPA-----------SDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANR 463
           TP            +D        A    +    TGRG   G   VP IK+   +     
Sbjct: 286 TPDPYWMQFGITNPNDSEGLMDLAACHSHIVFLVTGRGNVVGSAVVPCIKITGNSATYRA 345

Query: 464 WFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFN 518
             + MD +AG +  G  + +E+  +L     +VASG K   S+  G       + 
Sbjct: 346 MEEDMDFDAGPVLEGRCSQDEMAQRLLKMAAEVASGTKS-KSEALGHKEYFIPYK 399


>UniRef50_D2PZR0 D-galactarate dehydratase/Altronate hydrolase domain protein n=1
           Tax=Kribbella flavida DSM 17836 RepID=D2PZR0_9ACTO
          Length = 923

 Score =  403 bits (1035), Expect = e-110,   Method: Composition-based stats.
 Identities = 122/522 (23%), Positives = 211/522 (40%), Gaps = 38/522 (7%)

Query: 20  DTDNVAIIVNDNGLKAGTRFPDG---LELIEHIPQGHKVALLDIPANGEIIRYGEVIGYA 76
             DN AI      L AGT        + L   + +GH++ +  +     +  +      A
Sbjct: 29  PGDNAAICSRR--LDAGTVVDFAGTPVTLPHTVLEGHRIVVRPVRTGEALTSWQTPFARA 86

Query: 77  VRAIPRGSWIDESMVV----------LPEAPPLHTLPLATKVPEPLPPLEGY-------- 118
           +R +  G ++     +          LP AP     PL     +      G         
Sbjct: 87  LRDLAVGDYVCTPTSLAAVSARGVDGLPAAPSASNEPLDPYELDENAVHLGRQVTSVEQP 146

Query: 119 -TFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLY 177
            TF GY  A G  GT+N + +  +    +G V  + +             DGVV + H  
Sbjct: 147 GTFLGYPRAQGPAGTRNHVVLLATSSRSSGFVTELARRF-----DGAAAGDGVVPVAHTE 201

Query: 178 GCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVES 237
           G          ++        +LNPN G  V+V+    E L   + +      +  P   
Sbjct: 202 GAEQGTPNNLTLLLATL-AGFALNPNVGA-VLVVDTE-EDLVSGQAIRDFMAERGYPELQ 258

Query: 238 ASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGV 297
                    +  GF+  +     + E  L  ++ +QR   P ++L + +QCGGSDAFSGV
Sbjct: 259 VPHAFFT--RQAGFEQDLTAAGALIEPWLPVVDAQQRTEVPLADLWIALQCGGSDAFSGV 316

Query: 298 TANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLN 357
           TANP  G  +  ++R G T + +E  E+  A   +     +    +R L  ++ +   + 
Sbjct: 317 TANPLSGAVAREVIRHGGTAVLAETDELIGAEGYVLKNVRDLPTARRFLRTVQAFKERVG 376

Query: 358 MGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVE-VLSPGQRPTKRGLIYAATP 416
                   NPS GN   GL N+V K++G+  K  +   ++ V+   +     G ++  +P
Sbjct: 377 WHGHTAEGNPSGGNVYRGLYNIVLKSVGAARKLDRDVRLDHVIDYAEPVPGPGFVFMDSP 436

Query: 417 ASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIA 476
            +D      +VASG  +  FTTG G+      VP IK  T +   +     MD++AG   
Sbjct: 437 GNDLESIAGEVASGCNLIFFTTGNGSITNFPFVPTIKFVTTSARYDLLEAEMDVDAGRYL 496

Query: 477 TGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFN 518
           TG  +++ +  +     + VASG+    + +   H+Q++++ 
Sbjct: 497 TG-TSMDALTAETLDLTVRVASGEPS--AGERAGHSQVSIWR 535



 Score = 86.6 bits (213), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 59/328 (17%), Positives = 98/328 (29%), Gaps = 64/328 (19%)

Query: 137 GITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIH 196
            I  +  C   +   +    E +       V  +V L H  GCG +  A       RT+ 
Sbjct: 604 LILPTSLCSGQIALRLAGRAELEKWAGDA-VTRMVALPHTEGCGSSGGASEET-FARTLL 661

Query: 197 NISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVE 256
              L+PN     +++  GCEK   +       +  A P           +   G  ++ +
Sbjct: 662 GYLLHPNTR-MALLLEHGCEKTHNDYFRAKLVEAGADPSRFG---WASIQADGGLDAVTD 717

Query: 257 DILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGAT 316
            +          L   Q+       L V ++  G    S  TA  A+      LV  G +
Sbjct: 718 RVRDWFSSF--DLPAPQQVEGDVGALTVALEARG--PLSDDTAE-AMALIGHELVAAGGS 772

Query: 317 VMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGL 376
           V+ S       A  LL   +                   +    T      +PG      
Sbjct: 773 VVLSSR----GA--LLAHDSFR-----------------VAAFGT------TPG------ 797

Query: 377 ANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDF-VCGTQQVASGITVQV 435
                             +   L+ GQR    G      P +D+    T   A G+   +
Sbjct: 798 -----------------PVAPTLAHGQRLAAPGWHVMRMPGTDWMETATGFGAGGVQQIL 840

Query: 436 FTTGRGTPYGLMAVPVIKMATRTELANR 463
                GT      VPV+++++  E   +
Sbjct: 841 AHVAGGTLSAQRFVPVVEISSDPETVAK 868


>UniRef50_C9KKM7 Hydrolase, UxaA family n=1 Tax=Mitsuokella multacida DSM 20544
           RepID=C9KKM7_9FIRM
          Length = 352

 Score =  402 bits (1034), Expect = e-110,   Method: Composition-based stats.
 Identities = 123/342 (35%), Positives = 178/342 (52%), Gaps = 8/342 (2%)

Query: 172 GLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQ 231
            +N ++  G +  A    +  + +   + NPN  G V++IGLGCE +    L      + 
Sbjct: 8   AVNIVFNTGCSDVAANTAMSQKVLTGFACNPNVYG-VVIIGLGCETVPHAALREKIQKMT 66

Query: 232 AIPVESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGS 291
           + PV     VS   +   G    +E  ++ A    Q+   +Q+E  PASEL++G++CGGS
Sbjct: 67  SKPV-----VSFGIQDEGGTLKTIEKAVRAARDMAQQAGMQQKELFPASELLLGIECGGS 121

Query: 292 DAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEW 351
           DA SG+  NPAVG  SD+LV  GA+ M SE  E     H+L  RA   E+ + ++   E 
Sbjct: 122 DATSGIACNPAVGELSDILVDMGASAMMSESIEWIGGEHVLAKRAATPEIQREIIRVCEE 181

Query: 352 YDNYLNMGKTD-RSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGL 410
           Y+ +L     D R+  P+PGNK GGL+ + EK+LG I K G   IVEVL    RPTKRG 
Sbjct: 182 YEKHLAGAGQDCRAGQPTPGNKAGGLSTLDEKSLGCIRKGGTRPIVEVLEQAVRPTKRGA 241

Query: 411 IYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDI 470
           +   T   D    T   A+G  V +FTTGRGTP G   VPV+K+           D MD 
Sbjct: 242 LVMDTAGYDISSVTSMAAAGCQVIIFTTGRGTPTGNAIVPVLKVTANARTYRCMEDNMDA 301

Query: 471 NAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHN 512
           +   I  GE+T ++ G +L   I   A+G + T ++ +G  +
Sbjct: 302 DLSAIVRGEKTYQQAGRELVDAIAATANG-RLTKAEAFGFSD 342


>UniRef50_D2S1M0 Altronate dehydratase n=1 Tax=Haloterrigena turkmenica DSM 5511
           RepID=D2S1M0_9EURY
          Length = 395

 Score =  398 bits (1022), Expect = e-109,   Method: Composition-based stats.
 Identities = 135/405 (33%), Positives = 198/405 (48%), Gaps = 24/405 (5%)

Query: 119 TFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYG 178
           TF GYR  DG +G +N + +  +    + V D +                 V    H  G
Sbjct: 3   TFSGYRREDGRIGVRNRVAVLPTSVAASAVADRIAANGGPR----------VTATPHQMG 52

Query: 179 CGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESA 238
                  PA     R +  I  NPN GG  +V+ LG E          +     I     
Sbjct: 53  TEQ--PEPARRRTERVLAGIGRNPNVGG-ALVVELGTEGAD------ASAIADEIAAADT 103

Query: 239 SIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVT 298
            + +L      G ++ V+   +  +  L++  + + ET  ASELV G++CGGSDA SG+ 
Sbjct: 104 PVETLSIRDAGGTRATVDRGRETVDALLEEAARARLETADASELVFGVECGGSDATSGIA 163

Query: 299 ANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLN- 357
           ANPAVG A D LV  G T  FSE  E   A H+L  R V+E V +RL+E +E  ++  + 
Sbjct: 164 ANPAVGNACDRLVEAGGTSCFSETPEFIGAEHILAERCVDESVRERLIECVERRESVADL 223

Query: 358 MGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQR-PTKRGLIYAATP 416
           MG   R   P+PGN++GGL  + EK+LG+IAK G + I +V+      P   GL+   TP
Sbjct: 224 MGVDLRGTQPTPGNQEGGLTTIEEKSLGAIAKGGTTPIRDVIDYADPLPIGGGLVVMDTP 283

Query: 417 ASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIA 476
             D      +VA G  V  FTTGRG+  G    PVIK+    + A R    MD++A T+ 
Sbjct: 284 GYDVESVVGKVAGGAQVIAFTTGRGSTTGNPIAPVIKVTGNPQTAERMATNMDVDASTVL 343

Query: 477 TGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAP 521
            GE ++E VG +++  +L VA G + T +++ G+  + A+    P
Sbjct: 344 DGE-SVEAVGERVYETLLSVADGTR-TEAERRGM-AEFAINELQP 385


>UniRef50_C5EFV8 Hydrolase n=1 Tax=Clostridiales bacterium 1_7_47FAA
           RepID=C5EFV8_9FIRM
          Length = 385

 Score =  395 bits (1015), Expect = e-108,   Method: Composition-based stats.
 Identities = 109/406 (26%), Positives = 182/406 (44%), Gaps = 25/406 (6%)

Query: 116 EGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNH 175
              TF GY   DG  G +N + I ++      +   V ++           ++G + +  
Sbjct: 1   MRKTFMGYARPDGRYGVRNYVAIISTADNSNFIARRVAQM-----------INGTIPVCP 49

Query: 176 LYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPV 235
            +G G     P   + I+T+  +  NPN    V+V                      I  
Sbjct: 50  CFGRGEI--GPDMDLHIKTMGGMGANPNVHSAVVV---------SLEPALAEKIAAVIRA 98

Query: 236 ESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFS 295
                 +   ++  G     E  ++ A R + + +  QR       L +G++CGGSD  S
Sbjct: 99  TGKKAETFSMDECGGSIGCTEQAVRAARRLIIEASMEQRVEVGIEHLHLGVECGGSDTTS 158

Query: 296 GVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNY 355
           G+ +NPA G  +D LV  G TV+ SE TE   A ++L  RAV  E+G+R+++ + WY++Y
Sbjct: 159 GLVSNPATGLVADQLVDAGGTVILSETTEWMGAENILLKRAVTPELGERIVKAIRWYEDY 218

Query: 356 LNM-GKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAA 414
           +   G      NP+P N KGGL+ + EKALGSI K G   I ++L+  + P + G+    
Sbjct: 219 IKSIGVDLNGFNPAPDNIKGGLSTIEEKALGSIKKGGTRPIQDMLTCSEAPGRPGMYLMD 278

Query: 415 TPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGT 474
            P       T    +G  + +F+TG+G P G    P IK+        +  + +D++   
Sbjct: 279 APTGGVENTTALAGAGCQLIIFSTGKGNPLGNPIAPTIKVTGNERTIGKSGENIDVDLSA 338

Query: 475 IATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPA 520
           + T +  I+  G  L+  ++D A GK  T ++  G   ++AV    
Sbjct: 339 VITEDMDIQAAGNILYEKMIDHADGKLTT-AEALGDL-EIAVTRIG 382


>UniRef50_B1M8U1 Altronate dehydratase n=55 Tax=root RepID=B1M8U1_METRJ
          Length = 426

 Score =  389 bits (999), Expect = e-106,   Method: Composition-based stats.
 Identities = 120/438 (27%), Positives = 183/438 (41%), Gaps = 30/438 (6%)

Query: 87  DESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVGTKNLLGITTSVHCVA 146
            E         P      A             TF G+R  +G VG +N + +        
Sbjct: 10  HEIATPFVGGAPDQFATKALATERASENYTAATFMGWRRENGRVGVRNHVVLLPLDDLSN 69

Query: 147 GVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGG 206
              + V             NV G + L H YG           +  RT+  I  NPN   
Sbjct: 70  AACEAVAN-----------NVKGTMALPHAYGRLQF--GEDLDLHFRTLIGIGSNPNVAA 116

Query: 207 EVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQIAERHL 266
            V++   G E     R+      V+ I      +V    E H G  ++V      A+R +
Sbjct: 117 VVVI---GIEDQWTNRV------VEGIARTGKPVVGFGIEGH-GDIAIVAKASYQAKRFV 166

Query: 267 QKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVR 326
           Q   + QRE CP ++L V  +CG SD  +G+ + P VG   D L+  G   +F E +E+ 
Sbjct: 167 QWATELQREECPIADLWVSTKCGESDTTTGLASCPTVGNMYDKLIPHGIYGVFGETSEIT 226

Query: 327 DAIHLLTPRAVNEEVGKRLLEEMEWY-DNYLNMGKTD--RSANPSPGNKKGGLANVVEKA 383
            A HL   RA++ EV  +     + Y D+ +   KTD    + P+ GN  GGL  + EKA
Sbjct: 227 GAEHLCRERAISPEVSDKWYAMWKAYQDDVIEAHKTDDLSDSQPTKGNIAGGLTTIEEKA 286

Query: 384 LGSIAKSGKSA-IVEVLSPGQRPTK-RGLIYAATPASDFVCGTQQVASGITVQVFTTGRG 441
           LG++ K G     ++ L P + PTK  GL +  T ++   C T   A+G  V  F TG+G
Sbjct: 287 LGNLEKIGHECRFIDALQPAEAPTKGPGLYFMDTSSAAAECVTLMAAAGYVVHTFPTGQG 346

Query: 442 TPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKK 501
              G   VPVIK+           + +D++   + T E TI + G  L   ++  A+G +
Sbjct: 347 NVIGNPIVPVIKITGNPRTVRTMGEHIDVDVSGVLTREMTIPQAGDALIDMVVRTANG-R 405

Query: 502 KTFSDQWGLHNQLAVFNP 519
            T ++  G H +  +   
Sbjct: 406 LTAAESLG-HREFVMTKL 422


>UniRef50_B5IW17 D-galactarate dehydratase / Altronate hydrolase, C terminal domain
           superfamily n=1 Tax=Thermococcus barophilus MP
           RepID=B5IW17_9EURY
          Length = 394

 Score =  387 bits (994), Expect = e-106,   Method: Composition-based stats.
 Identities = 107/406 (26%), Positives = 190/406 (46%), Gaps = 33/406 (8%)

Query: 120 FEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGC 179
            +G+R  +G  G +N + + +SV C       + +              G + +    G 
Sbjct: 6   IKGWRRENGDFGIRNHIVVLSSVACANHAALEIARRT------------GAIPIIQEEG- 52

Query: 180 GVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESAS 239
              +        +R + N+  +PN     +V+GLGCE +   +L               +
Sbjct: 53  ACGMFGEDRKRFLRCMANVGSHPNVAWT-LVVGLGCEGIDAHQLADEISK------RGRN 105

Query: 240 IVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTA 299
             SL  +  +G    VE  +++  R  + L   +RET    ELV+G++CG SD  SG+ +
Sbjct: 106 AESLLIQ-ELGMDKTVEKGIELVNRAKENLTP-RRETAGVEELVIGLKCGASDYTSGLIS 163

Query: 300 NPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEME-WYDNYLNM 358
           NP+VG A D+L+  G T + +E  E+  A  +L  RA ++EV +  L  ++   ++    
Sbjct: 164 NPSVGKAVDILIEYGGTAIITERLELVGAEQILARRAKSKEVAEDFLRRIKKAVEDVNKR 223

Query: 359 GKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPAS 418
           G     + PS GN KGGL  + EK+LG++ K+G + +   L  G++P  RGL +   P  
Sbjct: 224 GVDWIGSQPSMGNIKGGLTTIEEKSLGAVKKAGNAQLEGCLDYGEKPKGRGLYFMDGPGY 283

Query: 419 DFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAG----T 474
           D    +  + +G  + +FTTG GT  G    PVIK+      A +  D +D++       
Sbjct: 284 DVKAVSGLMCAGSHIILFTTGLGTYLGSPVSPVIKITGNPTTARKLRDAIDVDLSILLEE 343

Query: 475 IATGEETIEEV----GWKLFHFILDVASGKKKTFSDQWGLHNQLAV 516
           I + + +++E+    G  +   I+ VA+GK  T +++   H + ++
Sbjct: 344 IISRDASLDEILEIGGRMILEEIVRVANGK-LTKAEK-SQHIEFSI 387


>UniRef50_Q0KC73 D-Galactarate dehydratase n=4 Tax=Burkholderiales
           RepID=Q0KC73_RALEH
          Length = 386

 Score =  384 bits (987), Expect = e-105,   Method: Composition-based stats.
 Identities = 107/391 (27%), Positives = 181/391 (46%), Gaps = 24/391 (6%)

Query: 116 EGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNH 175
              TF GY   +G+VG +N + + + +     V   + + +   +      V G  G + 
Sbjct: 3   MTATFLGYPRENGAVGVRNWVAVVSVMDNCNPVTRTIARTVGGCIPVTTLFVRGQFGADL 62

Query: 176 LYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPV 235
            +                ++  +  NPN    V+++GL           +  +  + I  
Sbjct: 63  DFA-------------FESLAGLGRNPNIAA-VLLVGL--------EESSTEEVARRIRS 100

Query: 236 ESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFS 295
               +  +  +   G  + + +  + A R     ++ +R  CP S LV+G++CGGSD  S
Sbjct: 101 TGKPVECVHLQPD-GTVACIAEGTRKASRLSLAASKARRVPCPVSSLVIGVECGGSDTTS 159

Query: 296 GVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDN- 354
           G++ NP +G  +D++V  G TV+ SE +E   A HL   RA +  V +  +  +   ++ 
Sbjct: 160 GLSCNPVIGRMADMVVAGGGTVIISETSEFIGAEHLFAERAADGRVREAFVTAVRNMEDL 219

Query: 355 YLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAA 414
            ++ G   R   PSP NK+GGL  V EKALG++AK+G S +V VL  G+ P K+GL +  
Sbjct: 220 AISRGVDMREDQPSPDNKRGGLTTVEEKALGAMAKAGTSPLVGVLRYGEAPQKKGLHFMD 279

Query: 415 TPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGT 474
            PA+     T   A G  +  F TG G P G M  P +K+       +   D +D +   
Sbjct: 280 APAAAVENLTALAAGGCQLTFFGTGVGNPIGSMVAPTVKVCGNVNTLHTMADNIDFDVSG 339

Query: 475 IATGEETIEEVGWKLFHFILDVASGKKKTFS 505
           +    + I ++G +LF + +DVASG + T  
Sbjct: 340 VLQNGDKISDLGEQLFGYAMDVASGTRLTSE 370


>UniRef50_C5EF38 Altronate dehydratase n=2 Tax=Clostridiales RepID=C5EF38_9FIRM
          Length = 405

 Score =  383 bits (983), Expect = e-104,   Method: Composition-based stats.
 Identities = 115/413 (27%), Positives = 179/413 (43%), Gaps = 39/413 (9%)

Query: 118 YTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLY 177
           ++++GY    G+ G +N + +  +V C   V   +V+         +P+V+ +VG +   
Sbjct: 4   WSWQGYGRKHGAPGIRNRVLVIYTVKCSEFVARRIVEE------SGHPDVE-LVGFD--- 53

Query: 178 GCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVES 237
             G   N  A  +    + ++  +PN G  V+ +GLGCE +QP+ L     DV     + 
Sbjct: 54  --GCTDNQYAVDL----LISLIKHPNVGA-VLTVGLGCEYIQPQWLA----DVAVKEGKE 102

Query: 238 ASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGV 297
           AS +S+Q E   G +  V          L++L    R      +LV+G +CGGSD  SG+
Sbjct: 103 ASWMSIQQE--GGTKPTVTKGTAWVRETLERLKHTPRVRMGFKDLVIGAECGGSDYTSGL 160

Query: 298 TANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLN 357
             N  VG   D LV  G   +F E+ E      LL  RA + E  +   E    YD  L+
Sbjct: 161 AGNVVVGRFFDRLVDLGGCAIFEEIVEAIGLDGLLVGRAADPEAAR---ELRYTYDKALD 217

Query: 358 MGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAA-TP 416
             ++ R  + SPGN  GGL+ + EK++G++ KSG   I  VL     P   GL     TP
Sbjct: 218 YCRSVRQYSVSPGNFAGGLSTIEEKSMGAVIKSGSRPIEGVLKVSVPPKHGGLWLLDSTP 277

Query: 417 A-----------SDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWF 465
                       +D       ++ G  +    TGRG   G    P IK+    E  +R  
Sbjct: 278 DPHFMQFGITNPNDNEGLMDLISCGAHIVFLVTGRGNVVGSAVAPCIKITGNHETFSRME 337

Query: 466 DLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFN 518
           + MD +A  I  G  + +E+   L  ++   A G   T S+  G       + 
Sbjct: 338 EDMDFDASPILYGGMSQKEMALDLAAYVAGTA-GGTPTKSEVLGHKEFYIPYK 389


>UniRef50_A7VSH2 Putative uncharacterized protein n=1 Tax=Clostridium leptum DSM 753
           RepID=A7VSH2_9CLOT
          Length = 404

 Score =  382 bits (982), Expect = e-104,   Method: Composition-based stats.
 Identities = 110/409 (26%), Positives = 169/409 (41%), Gaps = 36/409 (8%)

Query: 121 EGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCG 180
           +GY  ADGS G +N + +  +V C   + + + +  +        +V+ V       G  
Sbjct: 8   QGYVRADGSKGIRNKVLVIYTVECCRALSERIARHFQE----LGQDVEAV-------GTS 56

Query: 181 VAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASI 240
             ++  A    IR +   S +PN G  V+ IG GCE  +P+++                 
Sbjct: 57  SCLDNQA---DIRRLLRFSTHPNVGA-VLAIGHGCEYTKPQKIAEFA------RQRGRES 106

Query: 241 VSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTAN 300
                ++  G     +  L+I    L+KL    RE    SELV+  +CGGSD  SG+  N
Sbjct: 107 QWFYQQEAGGSVKGYDKGLEIVRELLKKLEATPREPMYLSELVLAGECGGSDFTSGLAGN 166

Query: 301 PAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGK 360
             +G   D LV  G T +F E+ E       L  RA    V   +      YD  +    
Sbjct: 167 ALIGRVFDRLVDAGGTAIFEELCEGLGLKEYLAARAATPRVADDI---RRAYDKTMEFCV 223

Query: 361 TDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATP---- 416
                + +PGN  GGL  + EK++G++ KSG   I  VL   Q P K GL    T     
Sbjct: 224 KYGHFSIAPGNMDGGLTTIEEKSMGAMVKSGTRPIRGVLKIAQAPKKPGLYLLDTTPDEK 283

Query: 417 -------ASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMD 469
                  A+D       +A G  +    TGRG   G    PVIK+        R  D +D
Sbjct: 284 LEPAHHEAADPSDMLDLIACGAHIVFLVTGRGHVVGTPVSPVIKVTGNPRTYGRMKDDID 343

Query: 470 INAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFN 518
             A    TG+ +++++   L   +  VA G++ T +++ G    +  FN
Sbjct: 344 FCAAPALTGDRSLDDLSDDLLELVSRVAQGER-TNAERLGHREGILYFN 391


>UniRef50_Q13SA4 Altronate dehydratase n=48 Tax=Bacteria RepID=Q13SA4_BURXL
          Length = 450

 Score =  379 bits (973), Expect = e-103,   Method: Composition-based stats.
 Identities = 124/430 (28%), Positives = 185/430 (43%), Gaps = 27/430 (6%)

Query: 101 TLPLATKVPEPLPPLEGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDL 160
           T+   T V  P    +  T +GY   DG  G +N++ +   V C   V   +V      L
Sbjct: 10  TIMTDTSVASPSAASQQPTLQGYLRRDGRKGIRNVVAVAYLVECAHHVAREIVTQFREPL 69

Query: 161 LPKYPNVDGVVGLNHLYGC-GVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQ 219
                         HL G  G   N+ A  +  R    ++ +PN G  V+ + LGCE + 
Sbjct: 70  DAFDDPSAEREPPVHLIGFPGCYPNSYAEKMLER----LTTHPNVGA-VLFVSLGCESMN 124

Query: 220 PERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPA 279
              L      V  +      +  L  ++  G +S ++  +       ++L  +Q+     
Sbjct: 125 KHYL------VDVVRASGRPVEVLTIQEKGGTRSTIQYGVDWIRSARKQLAAQQKVPMAL 178

Query: 280 SELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNE 339
           SELV+G  CGGSD  SG+TANPAVG A D L+  GAT +F E  E+      +  RA   
Sbjct: 179 SELVIGTICGGSDGTSGITANPAVGRAFDHLIDAGATCIFEETGELVGCEFHMKTRAARP 238

Query: 340 EVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVL 399
           E+G+ ++  +     Y ++      A    GN  GGL    EK+LG+ AKSG S IV ++
Sbjct: 239 ELGEEIVACVAKAARYYSILGHGSFAV---GNADGGLTTQEEKSLGAYAKSGASPIVGIV 295

Query: 400 SPGQRPTKRGLIYAA-----------TPASDFVCGTQQVASGITVQVFTTGRGTPYGLMA 448
            PG  P   GL                  SD     + +A G  V +FTTGRG+  G   
Sbjct: 296 KPGDIPPTGGLYLLDVVPDGEPRFGFPNISDNAEIGELIACGAHVILFTTGRGSVVGSAI 355

Query: 449 VPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQW 508
            PVIK+             MD++AG I  G  T++EVG ++F   + V+ G     S+  
Sbjct: 356 SPVIKVCANPATYRNLAGDMDVDAGRILEGRGTLDEVGREVFEQTVAVSRGAAS-KSETL 414

Query: 509 GLHNQLAVFN 518
           G    +  + 
Sbjct: 415 GHQEFILTYK 424


>UniRef50_A8H9C8 D-galactarate dehydratase/Altronate hydrolase domain protein n=3
           Tax=Proteobacteria RepID=A8H9C8_SHEPA
          Length = 393

 Score =  340 bits (873), Expect = 6e-92,   Method: Composition-based stats.
 Identities = 110/393 (27%), Positives = 176/393 (44%), Gaps = 33/393 (8%)

Query: 119 TFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYG 178
           +F G+   DGSVG +N + I     C  G+   +   I+          +G+V  N+   
Sbjct: 4   SFIGFGRTDGSVGIRNHVLIMAVDECCDGIARAIADSID----------NGIVVTNYNT- 52

Query: 179 CGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESA 238
           C    N       I T+ +   NPN  G V+V+ +GC  + PE +         I     
Sbjct: 53  CMYGGNEE----MINTMIHTGNNPNVAG-VLVLAMGCGSIDPEIVAA------PIRETGR 101

Query: 239 SIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVT 298
              SL   K  G ++ +    ++A++  Q      R   P SEL++G++CGGSD  SG+ 
Sbjct: 102 PAFSLVCMKQQGTRATINQGKELAQQLQQAAQDAPRVEKPISELIIGVKCGGSDTSSGIA 161

Query: 299 ANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNM 358
           +NP+VG A D LV  GAT +  E+ E+     +L  RAV+ EV  +L   +  +      
Sbjct: 162 SNPSVGRAVDTLVDMGATAIAGELIELVGCESILRQRAVSTEVADKLERLI--HQEEARW 219

Query: 359 GKTDRS-ANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPG----QRPTKRGLIYA 413
                     S GN  GGL  + EK+ G+++K+G  AI +VL       ++PT  G   +
Sbjct: 220 HVDGAEVETMSIGNSVGGLTTLEEKSFGALSKTGTRAIQDVLQINHLVHEKPTTAGFYLS 279

Query: 414 ATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAG 473
                    G    A G  + ++TTG G  +    VPVI+++    L     + +DI+A 
Sbjct: 280 EATHLCGSAGMHFAALGAHLILWTTG-GAGFNNPIVPVIRVSGNQYL---LNEDIDIDAS 335

Query: 474 TIATGEETIEEVGWKLFHFILDVASGKKKTFSD 506
            I   EE +E V  ++   +  VA G++    +
Sbjct: 336 GIMRAEEGVESVAERIVAKVSKVAQGQQTNIEE 368


>UniRef50_B6WWW3 Putative uncharacterized protein n=2 Tax=Desulfovibrio
           RepID=B6WWW3_9DELT
          Length = 399

 Score =  338 bits (867), Expect = 4e-91,   Method: Composition-based stats.
 Identities = 102/412 (24%), Positives = 173/412 (41%), Gaps = 27/412 (6%)

Query: 120 FEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGC 179
           F G+   +G VG +N + +      VA +   +   +    L   PN +G          
Sbjct: 3   FWGFVRENGKVGIRNHVLVVGITRNVATLAYMIASSVRGTRLYVGPNENG---------- 52

Query: 180 GVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESAS 239
               +        R I  ++ NPN GG V+++G   +    E   T  + V+ I      
Sbjct: 53  ---RSRDDRETMARVITGLAKNPNVGG-VLLVGNKPDGGYAE--FTYENIVENIMASGKP 106

Query: 240 IVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTA 299
           + +L   +  G  + +   +Q A    +  + ++RE     +L + ++CG SDA SG+  
Sbjct: 107 VETLFISRDGGHAACIGLGIQKARHLAELCSAQRREEVDWGKLCIAVKCGYSDATSGMAG 166

Query: 300 NPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMG 359
           NP +GY  D L   G T +FSE TEV  A  ++  R  +       L  +   +      
Sbjct: 167 NPVIGYVFDRLCDAGGTAIFSETTEVIGAEEIVARRFADAGQRDVFLSCVRKVEEEAKAT 226

Query: 360 KTD-RSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPAS 418
             D RS NP P N + GL  + EK+LG+IAK+G   I++ +  G+ P+  GL Y  +  S
Sbjct: 227 GQDIRSINPIPANIEAGLTTLEEKSLGAIAKAGTKPIMQCVRYGESPSAPGLNYMDSWMS 286

Query: 419 DFVCGTQQVASGITVQVFTTGRGTPYGLMAVPV---------IKMATRTELANRWFDLMD 469
                    ++G  + +F  G G       +PV         +         +     +D
Sbjct: 287 SSALFAGFSSAGAVLNIFQFGGGAMPDKCMMPVADTGVVAPILFATGNPRAYDHGKLEID 346

Query: 470 INAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAP 521
            N+G + + + +IEE G KL   I D+ASG + T  +   +   + ++   P
Sbjct: 347 FNSGVVISEKASIEETGEKLIRHICDIASG-RMTKVETLNVREPVELYLQGP 397


>UniRef50_D0Z3R7 Altronate hydrolase n=2 Tax=Bacteria RepID=D0Z3R7_LISDA
          Length = 391

 Score =  323 bits (829), Expect = 8e-87,   Method: Composition-based stats.
 Identities = 113/394 (28%), Positives = 176/394 (44%), Gaps = 32/394 (8%)

Query: 116 EGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNH 175
              TF+G+   +G+ G +N + I     C  G+   + K I+          D VV  NH
Sbjct: 1   MTMTFKGFPRPNGTFGIRNNVMIVAIDECCEGIARNISKEID----------DSVVVTNH 50

Query: 176 LYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPV 235
            Y C    N       I TI + + NPN  G V+VI +GC  + PE +       + I  
Sbjct: 51  -YTCMYGGNEE----MIDTIIHTATNPNIAG-VLVIAMGCGSIDPEMVA------EPIRK 98

Query: 236 ESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFS 295
           E   + +L   K+ G    ++D L +A+      +  +R   P S L +G++CGGSD  S
Sbjct: 99  EGLPVHTLTVIKNKGTIETIKDGLVLAKELKAYADSVERIDAPISALRIGIKCGGSDTSS 158

Query: 296 GVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNY 355
           G+ +NP+VG ASD LV  GAT M  E+ E+     +L  R+V  EVG ++   +   ++ 
Sbjct: 159 GLASNPSVGAASDKLVDMGATTMAGELLELLGCEEILKARSVTPEVGSKIERLIA--EDL 216

Query: 356 LNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPG----QRPTKRGLI 411
                 + +   S GN  GGL  + EK+ G++ K+G   I + L       ++PTK G  
Sbjct: 217 KRWHVIEGTETMSIGNSVGGLTTIDEKSQGAMHKTGTQPIQDCLRINHIHREKPTKPGFY 276

Query: 412 YAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDIN 471
              T            + G  + ++T G    +    VPVI+++  + L       MDIN
Sbjct: 277 LTETTMLCGGAAMHFASLGCQLILWTAG-AAGFNNSIVPVIRVSGNSALITA---DMDIN 332

Query: 472 AGTIATGEETIEEVGWKLFHFILDVASGKKKTFS 505
           A  I    +TI+ V  K+   +  VA G      
Sbjct: 333 ACGIMDATDTIDNVSNKIIDKVFAVADGLPTNLE 366


>UniRef50_B5JYR2 D-Galactarate dehydratase n=1 Tax=Octadecabacter antarcticus 238
           RepID=B5JYR2_9RHOB
          Length = 359

 Score =  316 bits (810), Expect = 1e-84,   Method: Composition-based stats.
 Identities = 88/370 (23%), Positives = 153/370 (41%), Gaps = 13/370 (3%)

Query: 154 KIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGL 213
            + +R        V GV+ L   +  G  +    A +    I+ I  +PN G  ++V   
Sbjct: 2   ALTDRVTTLAAEQVPGVLPLTPAFQRG--LRGIDATLQHDMINAIIAHPNVGAALVVTHD 59

Query: 214 GCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQ 273
           G    Q  R                 IV +      G Q+  E +       L +  ++ 
Sbjct: 60  GASADQLRRFCAELG---------KPIVIVALMAQQGMQAACETMAAHLRSLLAEAAEQS 110

Query: 274 RETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLT 333
           +      +L V ++CGGSDA S + ANPA+G   D L+  G T + SE  E      ++ 
Sbjct: 111 KSKFLLPDLTVALECGGSDATSALCANPAIGRFVDRLIDAGGTAIVSETAEFLGGEDIVL 170

Query: 334 PRAVNEEVGKRLLEEMEWYDNYLNMGKTD-RSANPSPGNKKGGLANVVEKALGSIAKSGK 392
            ++   +V   +L  +   D  +    TD R  NP+  N + GL+ + EK +G++ K G 
Sbjct: 171 AQSRTPQVADAILAYLSAEDAIMTSDGTDYRGVNPTQENIEAGLSTLTEKTMGALCKIGT 230

Query: 393 SAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVI 452
           S     L+ G+ PT +GL +  TP       T  V  G  V +F  G   P GL   P I
Sbjct: 231 SRFAGALNFGEEPTGKGLFFMNTPFFSPTSLTGMVLGGAQVSLFAMGVFNPSGLPLAPTI 290

Query: 453 KMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHN 512
           K+    +  + W D +D++   + +G          +   + D+++G + T ++++    
Sbjct: 291 KICGNPKTLSDWPDAIDLDVSGVISGRMNYGAAADDILRIVRDISNG-QVTCAERFQEGQ 349

Query: 513 QLAVFNPAPV 522
            +     +P+
Sbjct: 350 IILPITQSPL 359


>UniRef50_D2S1L8 Altronate dehydratase-like protein n=1 Tax=Haloterrigena turkmenica
           DSM 5511 RepID=D2S1L8_9EURY
          Length = 373

 Score =  265 bits (678), Expect = 2e-69,   Method: Composition-based stats.
 Identities = 96/404 (23%), Positives = 153/404 (37%), Gaps = 47/404 (11%)

Query: 120 FEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGC 179
           F  Y      VG +N + +  SV C   V D +              V G V   H +GC
Sbjct: 13  FTAYDRDRDGVGVRNRVLVVPSVICSHTVADRIA-----------SEVPGAVSTPHDHGC 61

Query: 180 GVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESAS 239
           G   +        RT+  ++ NPN  G  + +GLGCE +Q +RL     D + +PVE  +
Sbjct: 62  GQLGDDSERTE--RTLVGVAANPNVAG-ALAVGLGCETVQSDRLAGSIAD-RGVPVEEVA 117

Query: 240 IVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTA 299
           I     ++  G  +  E  +  A   L+   +  R         +G+        S  TA
Sbjct: 118 I-----QRAGGTDACREAGIDRAT-ALRARTEATRSQVGLEAATIGVVSSDCRPSSLETA 171

Query: 300 NPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMG 359
           +P VG     +V  G   + +    V        P AV E V     E  E +D     G
Sbjct: 172 DPLVGSVVGRIVDAGGRALIAGNERVH-----AHPDAVRERVAT--AEARERFD-----G 219

Query: 360 KTDRSANPSPGNKKGGLANVVEKALGSIAKS-GKSAIVEVLSPGQRPTK-RGLIYAATPA 417
            TDR+ + SP           +     + +  G  ++ +VL  G+R T   G+     P+
Sbjct: 220 VTDRAYD-SPAAVTATRKRAADATPEQVRRLWGDRSVRDVLEYGERATHDAGVALVDAPS 278

Query: 418 SDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIAT 477
           +     T   A+G  + +  T  G P G   VPV+ +    +  +   D +D  AG    
Sbjct: 279 AFDEAATALAAAGAQIVIHVTADGIPAGHPIVPVLAVTGDRDTYDALCDDLDTFAG---- 334

Query: 478 GEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAP 521
                E    +L   +  V  G+  T S++ G+ +  A+    P
Sbjct: 335 -----ETTPDELLATLRAVLDGEP-TSSERHGVTS-FAITRVGP 371


>UniRef50_C8T5I2 D-galactarate dehydratase n=3 Tax=Enterobacteriaceae
           RepID=C8T5I2_KLEPR
          Length = 172

 Score =  212 bits (541), Expect = 2e-53,   Method: Composition-based stats.
 Identities = 139/166 (83%), Positives = 148/166 (89%)

Query: 1   MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDI 60
           MA+I IRQ++PTAFYIKV  TDNVAIIVND GL AGTRFPDGL L+EHIPQGHKVAL+DI
Sbjct: 1   MADIAIRQQSPTAFYIKVDPTDNVAIIVNDRGLTAGTRFPDGLTLVEHIPQGHKVALVDI 60

Query: 61  PANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTF 120
           PA+GEIIRYGEVIGYAVR IP+GSWIDES+V LP APPL+TLPLATKVPEPLPPLEGYTF
Sbjct: 61  PAHGEIIRYGEVIGYAVRDIPQGSWIDESLVELPTAPPLNTLPLATKVPEPLPPLEGYTF 120

Query: 121 EGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPN 166
           EGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKII        P 
Sbjct: 121 EGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIINATCCQTIPT 166


>UniRef50_B7DPM4 Altronate dehydratase n=1 Tax=Alicyclobacillus acidocaldarius LAA1
           RepID=B7DPM4_9BACL
          Length = 223

 Score =  172 bits (435), Expect = 4e-41,   Method: Composition-based stats.
 Identities = 39/192 (20%), Positives = 73/192 (38%), Gaps = 5/192 (2%)

Query: 12  TAFYIKVHDTDNVAIIVNDNGLKAGTRFPDG-LELIEHIPQGHKVALLDIPANGEIIRYG 70
            +  + +   D+V + +    +      P G +     + +GHK+A   +     + +YG
Sbjct: 2   ASKVLHLSPVDDVVVALEPLDVGEVVETPFGSVSARAPVSRGHKLADRHVQCGEPVRKYG 61

Query: 71  EVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSV 130
             IG A + I  G W+    +         +              +G TF GY  +DG V
Sbjct: 62  FPIGLAGQDIEPGEWVHTHNLRTALMERDDSYVYLPSGSPMPVLDDGLTFLGYVRSDGQV 121

Query: 131 GTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVV 190
           G +N + I  +V CV  V + +  + +     +   +DGV    H YGC    +      
Sbjct: 122 GVRNEIWILNTVGCVNKVAERLAAMADAR--WRGGGIDGVYHFAHPYGCSQLGDDLVYTQ 179

Query: 191 PIRTIHNISLNP 202
            +  +  +  +P
Sbjct: 180 SL--LAGLVRHP 189


>UniRef50_B9TLG0 Putative uncharacterized protein (Fragment) n=1 Tax=Ricinus
           communis RepID=B9TLG0_RICCO
          Length = 217

 Score =  140 bits (352), Expect = 2e-31,   Method: Composition-based stats.
 Identities = 48/219 (21%), Positives = 80/219 (36%), Gaps = 35/219 (15%)

Query: 15  YIKVHDTDNVAIIVNDNGLKAGTRF---PDGLELIEHIPQGHKVALLDIPANGEIIRYGE 71
            I +H  D++ + + D  L  G       + + +   +   HK+A         +  YG 
Sbjct: 4   VICIHPDDSMLVALTD--LAPGDVVTWNGENILVSTPVKTKHKLARRAFAEGDLLTMYGV 61

Query: 72  VIGYAVRAIPRGSWIDESMVVLPEAPPL--HTLPLATKVPEPLPPLEGYTFEGYRNADGS 129
           V+G A + I +G  +    +    +      + P     P+ +  L+  TF+G   ADG 
Sbjct: 62  VVGKATQPIRKGEAVTTDNLAHYASEVEIGESKPYTWTPPD-VSDLQDATFDGVVRADGR 120

Query: 130 VGTKNLLGITTSVHCVAGVVDYVVKIIERDLL-------------------------PKY 164
           VGT N   I   V C    V+++   +E  L                            +
Sbjct: 121 VGTANYWLIFPLVFCENRNVEHLRNALEGPLGYATNDLASLTFQLLGEDMEAPKPVVRPF 180

Query: 165 PNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPN 203
           PNVDGV  + H  GCG       A    + +   + +PN
Sbjct: 181 PNVDGVRIITHNGGCGGTR--ADARSLCKILAAYADHPN 217


>UniRef50_UPI00017F2C45 Altronate dehydratase n=2 Tax=Enterobacteriaceae
           RepID=UPI00017F2C45
          Length = 119

 Score =  129 bits (325), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 35/121 (28%), Positives = 50/121 (41%), Gaps = 6/121 (4%)

Query: 14  FYIKVHDTDNVAIIVNDNGLKAGTRFP---DGLELIEHIPQGHKVALLDIPANGEIIRYG 70
            YIK+H  DNVA+ + D  L  GT        + L + + +GHK AL +I     +I+YG
Sbjct: 2   QYIKIHALDNVAVALAD--LAEGTEVSVDNQTVRLRQDVARGHKFALTNIAKGANVIKYG 59

Query: 71  EVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSV 130
             IGYA+  I  G  +            L          +          + YR A+G V
Sbjct: 60  LPIGYALADIAAGEHVHAHNTR-TNLSDLDQYRYQPDFHDLPAQAADREVQIYRRANGDV 118

Query: 131 G 131
           G
Sbjct: 119 G 119


>UniRef50_UPI00017F3110 galactarate dehydratase n=1 Tax=Escherichia coli O157:H7 str.
          EC4024 RepID=UPI00017F3110
          Length = 114

 Score =  127 bits (319), Expect = 1e-27,   Method: Composition-based stats.
 Identities = 75/82 (91%), Positives = 80/82 (97%)

Query: 1  MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDI 60
          MA+IEIRQ +PTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVAL+DI
Sbjct: 1  MADIEIRQASPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALVDI 60

Query: 61 PANGEIIRYGEVIGYAVRAIPR 82
          PA+GEI+RYGEVIGYAVRAI R
Sbjct: 61 PAHGEIVRYGEVIGYAVRAIRR 82


>UniRef50_C5EFR7 Predicted protein n=1 Tax=Clostridiales bacterium 1_7_47FAA
          RepID=C5EFR7_9FIRM
          Length = 93

 Score = 97.4 bits (241), Expect = 1e-18,   Method: Composition-based stats.
 Identities = 27/79 (34%), Positives = 44/79 (55%), Gaps = 3/79 (3%)

Query: 16 IKVHDTDNVAIIVND--NGLKAGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRYGEVI 73
          I+  + DNVA+++ D   GL  G    D + + + IP GHK+AL DI A  ++ +YGE +
Sbjct: 9  IRFTEKDNVAVVLEDVKPGLVMGLDGAD-ITVGDEIPYGHKIALSDIAAGEKVYKYGEPV 67

Query: 74 GYAVRAIPRGSWIDESMVV 92
             ++ I +G W+    V 
Sbjct: 68 ARCIKDIKKGEWVHVHNVE 86


>UniRef50_A8MAM1 SAF domain protein n=5 Tax=cellular organisms RepID=A8MAM1_CALMQ
          Length = 106

 Score = 96.6 bits (239), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 28/92 (30%), Positives = 45/92 (48%), Gaps = 5/92 (5%)

Query: 6  IRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDG-----LELIEHIPQGHKVALLDI 60
          ++ E+     I +  +DNVA+ + D    +      G     ++LI++IP GHK AL DI
Sbjct: 1  MKAESTVKEAIVLSPSDNVAVALRDLKSGSLITLDVGSLRLTVKLIDNIPFGHKFALKDI 60

Query: 61 PANGEIIRYGEVIGYAVRAIPRGSWIDESMVV 92
          P    +++YG  IG A R I  G  +    + 
Sbjct: 61 PKCSLVVKYGHTIGRAKRDIKAGEHVHVHNLE 92


>UniRef50_C2DK38 Putative uncharacterized protein n=2 Tax=Escherichia
           RepID=C2DK38_ECOLX
          Length = 65

 Score = 94.7 bits (234), Expect = 8e-18,   Method: Composition-based stats.
 Identities = 58/64 (90%), Positives = 61/64 (95%)

Query: 286 MQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRL 345
           M CGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVT+V DAIHLLTPRA+NEEVG+ L
Sbjct: 1   MHCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTDVHDAIHLLTPRAINEEVGRCL 60

Query: 346 LEEM 349
           LEEM
Sbjct: 61  LEEM 64


>UniRef50_Q0RXU4 Possible sulfolactate sulfo-lyase small subunit n=1
          Tax=Rhodococcus jostii RHA1 RepID=Q0RXU4_RHOSR
          Length = 102

 Score = 93.9 bits (232), Expect = 1e-17,   Method: Composition-based stats.
 Identities = 32/99 (32%), Positives = 48/99 (48%), Gaps = 6/99 (6%)

Query: 6  IRQETPTAFYIKVHDTDNVAIIVNDNGLKAGT----RFPDG--LELIEHIPQGHKVALLD 59
          ++  T    ++  HD D VA+ V D    A      R P+   LEL++ IP GHKVAL+D
Sbjct: 1  MKNATRAPDFLAHHDGDVVAVAVRDLEPGAAEGGYLRGPESVSLELLDPIPLGHKVALVD 60

Query: 60 IPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPP 98
          + A  ++I YG  +G     I RGS++    +       
Sbjct: 61 LEAGQDVIEYGLRVGVTTEKITRGSYVHVHNIRSARWQN 99


>UniRef50_D1Y192 Mannonate dehydratase n=1 Tax=Pyramidobacter piscolens W5455
          RepID=D1Y192_9BACT
          Length = 89

 Score = 92.7 bits (229), Expect = 3e-17,   Method: Composition-based stats.
 Identities = 25/78 (32%), Positives = 40/78 (51%), Gaps = 1/78 (1%)

Query: 16 IKVHDTDNVAIIVNDNGLKAGTRFPDG-LELIEHIPQGHKVALLDIPANGEIIRYGEVIG 74
          +++   DNV  ++ D+        PDG L L++ +   HKV + D+ A   +I+YGE IG
Sbjct: 6  LQISPADNVKTVLEDSFRGDTIDTPDGPLTLLDDVEFAHKVLIKDLHAGDPVIKYGEEIG 65

Query: 75 YAVRAIPRGSWIDESMVV 92
                PRG+WI    + 
Sbjct: 66 RVKADTPRGTWIHTHNMS 83


>UniRef50_A7VSH3 Putative uncharacterized protein n=1 Tax=Clostridium leptum DSM
          753 RepID=A7VSH3_9CLOT
          Length = 136

 Score = 90.0 bits (222), Expect = 2e-16,   Method: Composition-based stats.
 Identities = 30/82 (36%), Positives = 42/82 (51%), Gaps = 6/82 (7%)

Query: 17 KVHDTDNVAIIVNDNGLKA----GTRFPDG--LELIEHIPQGHKVALLDIPANGEIIRYG 70
          +V   DNVA  + D    +    G   P G  +E ++ IP GHK+AL DI     II+YG
Sbjct: 18 QVSAQDNVATALGDIPAGSVSVTGDIGPQGKNIEALQEIPYGHKIALRDIKPGEFIIKYG 77

Query: 71 EVIGYAVRAIPRGSWIDESMVV 92
            I  A + IP+G+W+    V 
Sbjct: 78 VKIAVATQDIPKGAWVHLHNVR 99


>UniRef50_B9MJB7 SMP-30/Gluconolaconase/LRE domain protein n=1 Tax=Diaphorobacter
          sp. TPSY RepID=B9MJB7_DIAST
          Length = 197

 Score = 88.9 bits (219), Expect = 4e-16,   Method: Composition-based stats.
 Identities = 36/66 (54%), Positives = 44/66 (66%)

Query: 18 VHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRYGEVIGYAV 77
          +H  DNVAI+ ND GL AGTR   G  L++ +PQ HKVAL DIP  G + RY  VIGYA+
Sbjct: 1  MHPADNVAIVANDGGLPAGTRLAGGQVLVDKVPQAHKVALEDIPEGGAVRRYNVVIGYAL 60

Query: 78 RAIPRG 83
          + I  G
Sbjct: 61 KFIAAG 66


>UniRef50_B4D086 SAF domain protein n=1 Tax=Chthoniobacter flavus Ellin428
           RepID=B4D086_9BACT
          Length = 106

 Score = 88.9 bits (219), Expect = 4e-16,   Method: Composition-based stats.
 Identities = 24/100 (24%), Positives = 38/100 (38%), Gaps = 1/100 (1%)

Query: 13  AFYIKVHDTDNVAIIVNDNGLKAGTRFPDG-LELIEHIPQGHKVALLDIPANGEIIRYGE 71
              +++H  DNV  ++      A  R  D  + +   +P GHK+A   + A  +I++YG 
Sbjct: 7   PRLLRLHPADNVLTVIATLESGARIRVGDAEVVVPTRLPIGHKIAARALHAGEKIVKYGA 66

Query: 72  VIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEP 111
            IG A R I  G       V     P            + 
Sbjct: 67  PIGSASRDIAAGEHAHTHNVQSDYLPTFLREDQTRFFAQH 106


>UniRef50_B8FML5 SAF domain protein n=1 Tax=Desulfatibacillum alkenivorans AK-01
          RepID=B8FML5_DESAA
          Length = 88

 Score = 87.3 bits (215), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 2/80 (2%)

Query: 16 IKVHDTDNVAIIVNDNGLKAGTRFPDGL--ELIEHIPQGHKVALLDIPANGEIIRYGEVI 73
          I V+  DNVA+ + D G     R  + +    I  I   HKV L D+    ++I+YGE+I
Sbjct: 6  IMVNPADNVAVALEDIGQGEEVRVGEKVLCRTIADIAYSHKVLLKDLSEGEDVIKYGEII 65

Query: 74 GYAVRAIPRGSWIDESMVVL 93
          G A + + +G W+    + L
Sbjct: 66 GQAAQDLKQGEWVHTHNLTL 85


>UniRef50_C1XHK9 Altronate dehydratase n=2 Tax=Meiothermus RepID=C1XHK9_MEIRU
          Length = 118

 Score = 87.3 bits (215), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 27/86 (31%), Positives = 43/86 (50%), Gaps = 11/86 (12%)

Query: 16 IKVHDTDNVAIIVNDNGLKAGTRF---------PDGLELIEHIPQGHKVALLDIPANGEI 66
          +    TD+VA+ V D  LKAG               ++L+E IP GHK+AL D+P    +
Sbjct: 14 LAHKSTDDVAVAVAD--LKAGEELVIHSLEGGQTHRVKLLEDIPLGHKIALRDMPEGHVV 71

Query: 67 IRYGEVIGYAVRAIPRGSWIDESMVV 92
          I YGE +G   + + +G ++    + 
Sbjct: 72 IEYGEKVGRMTQPVKKGGYVHVHNIR 97


>UniRef50_C5EF39 Altronate hydrolase n=3 Tax=Clostridiales RepID=C5EF39_9FIRM
          Length = 112

 Score = 87.0 bits (214), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 32/80 (40%), Positives = 42/80 (52%), Gaps = 3/80 (3%)

Query: 13 AFYIKVHDTDNVAIIVNDNGLKAGTRFPDG---LELIEHIPQGHKVALLDIPANGEIIRY 69
          AF I + D    A+     G +AG     G   ++    IP GHK+AL DI A G I++Y
Sbjct: 7  AFQIDLGDNVATALAGIKAGQEAGLTGDHGEESIKAATDIPAGHKIALKDIGAGGHIVKY 66

Query: 70 GEVIGYAVRAIPRGSWIDES 89
          G VIG A   IP+GSW+   
Sbjct: 67 GVVIGRATADIPKGSWVHLH 86


>UniRef50_D2PG65 SAF domain protein n=15 Tax=cellular organisms RepID=D2PG65_SULIS
          Length = 100

 Score = 85.8 bits (211), Expect = 3e-15,   Method: Composition-based stats.
 Identities = 23/95 (24%), Positives = 41/95 (43%), Gaps = 12/95 (12%)

Query: 13 AFYIKVHDTDNVAIIVNDNGLKAGTRFPD----------GLELIEHIPQGHKVALLDIPA 62
            ++  +  DNV + + D  +KAG                ++ I +IP GHK+AL ++  
Sbjct: 2  PHFLIHNKNDNVGVAITD--IKAGEEVEGVYIEDMAKGPKIKAINNIPLGHKIALSNLKQ 59

Query: 63 NGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAP 97
             +I+YG  IG A++ I  G  +    +      
Sbjct: 60 GDTVIKYGRPIGSAIKEIKIGEHVHVHNIKSNRWG 94


>UniRef50_Q5WIZ0 Altronate hydrolase N-terminus n=5 Tax=Bacteria
          RepID=Q5WIZ0_BACSK
          Length = 96

 Score = 83.1 bits (204), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 28/85 (32%), Positives = 36/85 (42%), Gaps = 2/85 (2%)

Query: 10 TPTAFYIKVHDTDNVAIIVND--NGLKAGTRFPDGLELIEHIPQGHKVALLDIPANGEII 67
          + T  ++ +   DNVA  + D   G          L L  HI  GHK AL  I    +I 
Sbjct: 2  SETKTHVVMQQKDNVATALRDFEKGQVVTLAGEQRLHLKNHIGFGHKFALCPIKKGADIT 61

Query: 68 RYGEVIGYAVRAIPRGSWIDESMVV 92
          +YGEVIG A   I  G  +    V 
Sbjct: 62 KYGEVIGVASTDIAAGEHVHLHNVE 86


>UniRef50_Q9HIE8 Putative uncharacterized protein Ta1392 n=1 Tax=Thermoplasma
          acidophilum RepID=Q9HIE8_THEAC
          Length = 95

 Score = 83.1 bits (204), Expect = 3e-14,   Method: Composition-based stats.
 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 11/82 (13%)

Query: 20 DTDNVAIIVNDNGLKAGTRFPDG---------LELIEHIPQGHKVALLDIPANGEIIRYG 70
            D+VA+  +D  LK G               +   E IP GHK++L DI     +I YG
Sbjct: 12 KNDSVAVATDD--LKEGEEIQVAFLDNNEKTKITTAEVIPLGHKISLKDIKKGENVIEYG 69

Query: 71 EVIGYAVRAIPRGSWIDESMVV 92
          EVIG A + I RG  +    + 
Sbjct: 70 EVIGAATKDIKRGEHVHIHNIK 91


>UniRef50_B4TB53 Hydrolase, UxaA family n=14 Tax=Bacteria RepID=B4TB53_SALHS
          Length = 96

 Score = 82.7 bits (203), Expect = 3e-14,   Method: Composition-based stats.
 Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 9/82 (10%)

Query: 18 VHDTDNVAIIVNDNGLKAGTRF-------PDGLELIEHIPQGHKVALLDIPANGEIIRYG 70
          +H  D VA  +    LKAG             + L + +P GHK A+ D+P +GE+ +YG
Sbjct: 8  IHPQDCVATAIT--ALKAGETATMFVGEREISVVLHQDVPFGHKFAICDVPFHGEVYKYG 65

Query: 71 EVIGYAVRAIPRGSWIDESMVV 92
          E IG A + I  G ++    V 
Sbjct: 66 ESIGRATQEIKSGDYVHVHNVE 87


>UniRef50_C8ZXV8 D-galactarate dehydratase n=1 Tax=Enterococcus gallinarum EG2
          RepID=C8ZXV8_ENTGA
          Length = 99

 Score = 82.3 bits (202), Expect = 4e-14,   Method: Composition-based stats.
 Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 7/97 (7%)

Query: 1  MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLEL-----IEHIPQGHKV 55
          M+  ++RQ   TA  ++    DNVA+++     ++     +   L     ++ I   HK 
Sbjct: 1  MSEEKVRQSMYTALMMR--PEDNVAVVLQPTPAESFVNIVNQASLNEFLIVQSIDSYHKF 58

Query: 56 ALLDIPANGEIIRYGEVIGYAVRAIPRGSWIDESMVV 92
          ++ DI    EII+YGEVIG A  AI +G  +    V 
Sbjct: 59 SVKDIEFGEEIIKYGEVIGIATAAIAKGEHVHTHNVR 95


>UniRef50_Q6L322 Altronate hydrolase n=1 Tax=Picrophilus torridus
          RepID=Q6L322_PICTO
          Length = 98

 Score = 82.3 bits (202), Expect = 4e-14,   Method: Composition-based stats.
 Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 5/79 (6%)

Query: 18 VHDTDNVAIIVNDNGLK-----AGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRYGEV 72
          + + DNVA ++  +         G      +   + IP GHK+A+ +I     +I+YGE+
Sbjct: 10 IDEKDNVATLLEGSKAGEKVQLKGLTCEKSIICNQDIPSGHKIAIKNIKLGESVIKYGEI 69

Query: 73 IGYAVRAIPRGSWIDESMV 91
          IG A + I  G ++    +
Sbjct: 70 IGRATKEIKIGDYVHIHNI 88


>UniRef50_C0GPG6 SAF domain protein n=1 Tax=Desulfonatronospira thiodismutans
          ASO3-1 RepID=C0GPG6_9DELT
          Length = 99

 Score = 80.8 bits (198), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 28/79 (35%), Positives = 38/79 (48%), Gaps = 5/79 (6%)

Query: 18 VHDTDNVAIIVNDNGLKAGTRFPDG-----LELIEHIPQGHKVALLDIPANGEIIRYGEV 72
          ++  DNVA    D  +       D      +++ E +  GHK AL DI   G+II+YGEV
Sbjct: 8  INKDDNVATATKDLDVGEKVLVQDDDSTFEIQVKEPVTFGHKFALSDISQGGQIIKYGEV 67

Query: 73 IGYAVRAIPRGSWIDESMV 91
          IG A R I R   +    V
Sbjct: 68 IGVATRDISRFGHVHVHNV 86


>UniRef50_D2NF82 Truncated altronate dehydratase n=2 Tax=Escherichia coli
           RepID=D2NF82_ECOLX
          Length = 108

 Score = 80.8 bits (198), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 22/98 (22%), Positives = 39/98 (39%), Gaps = 1/98 (1%)

Query: 16  IKVHDTDNVAIIVNDNGLKAGTRFPDG-LELIEHIPQGHKVALLDIPANGEIIRYGEVIG 74
           +K+H  DN  + +ND        + +G +     +  GHK+A   +     I++YG +IG
Sbjct: 11  LKLHAKDNCVVALNDIASGDIVWWDEGEMVACSSVTLGHKLACEALNNGDSILKYGAIIG 70

Query: 75  YAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPL 112
           +A R I  G  +    +        H      +  E  
Sbjct: 71  HATRDIAMGEHVHSHNLASNAIAIFHHDDAGYQSEEKA 108


>UniRef50_C3WAI6 Carbohydrate hydrolase n=2 Tax=Bacteria RepID=C3WAI6_FUSMR
          Length = 93

 Score = 80.0 bits (196), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 9/82 (10%)

Query: 18 VHDTDNVAIIVNDNGLKAGTRFPD-------GLELIEHIPQGHKVALLDIPANGEIIRYG 70
          +   DNVA+ +    +K G             LE +  +   HK+A  DI     +++YG
Sbjct: 8  IDKKDNVAVAIE--TVKKGEVVAYKLDNETVSLEALTDVQIYHKLASKDIKKGEPVVKYG 65

Query: 71 EVIGYAVRAIPRGSWIDESMVV 92
          E IG A R I +G  +    V 
Sbjct: 66 EHIGIAGRDIQKGEHVHVHNVE 87


>UniRef50_B8IQB2 SAF domain protein n=8 Tax=Proteobacteria RepID=B8IQB2_METNO
          Length = 105

 Score = 80.0 bits (196), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 28/93 (30%), Positives = 40/93 (43%), Gaps = 10/93 (10%)

Query: 13  AFYIKVHDTDNVAIIVNDNGLKAGT-----RFPDG----LELIEHIPQGHKVALLDIPAN 63
              +     DNVA+ V    LKAGT        D     +E+   IP GHKVAL D+   
Sbjct: 14  PHLLAHSPLDNVAVAVV-EDLKAGTAAFGVVTQDNSTFEVEVRHDIPIGHKVALADLKTG 72

Query: 64  GEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEA 96
              I+YG+ IG  ++ + +G  +    V     
Sbjct: 73  DTAIKYGQDIGRVIKDVAKGEHVHVHNVKTKRW 105


>UniRef50_B8FVM2 SAF domain protein n=4 Tax=Desulfitobacterium hafniense
          RepID=B8FVM2_DESHD
          Length = 98

 Score = 79.6 bits (195), Expect = 3e-13,   Method: Composition-based stats.
 Identities = 21/92 (22%), Positives = 35/92 (38%), Gaps = 11/92 (11%)

Query: 15 YIKVHDTDNVAIIVNDNGLKAGTRF---------PDGLELIEHIPQGHKVALLDIPANGE 65
          ++     D+V + V D  +KAG +             +     I  GHK+AL        
Sbjct: 6  FLLHEAQDDVGVAVQD--IKAGEKVMGVDIHSGEEFHVTANHDIQLGHKIALKSKKQGEN 63

Query: 66 IIRYGEVIGYAVRAIPRGSWIDESMVVLPEAP 97
          +I+YGE +G   + I  G W+    +      
Sbjct: 64 LIKYGENVGKVTQDIKVGDWVHTHNLKTARWD 95


>UniRef50_Q3ACL1 Hydrolase, UxaA family n=1 Tax=Carboxydothermus hydrogenoformans
          Z-2901 RepID=Q3ACL1_CARHZ
          Length = 97

 Score = 79.6 bits (195), Expect = 3e-13,   Method: Composition-based stats.
 Identities = 22/82 (26%), Positives = 38/82 (46%), Gaps = 5/82 (6%)

Query: 16 IKVHDTDNVAIIVNDNGLKAGTRFP-----DGLELIEHIPQGHKVALLDIPANGEIIRYG 70
          I +++ DNVA ++ D  L     F        +   E+IP  HK+A+ ++     + +YG
Sbjct: 8  IVINENDNVATVIEDINLGDVVVFEILGKTQEIIARENIPIYHKIAIKEVRVGEYVYKYG 67

Query: 71 EVIGYAVRAIPRGSWIDESMVV 92
          + IG A R I  G  +    + 
Sbjct: 68 QKIGVATRDIQIGEHVHSHNLS 89


>UniRef50_B1B868 Altronate hydrolase n=7 Tax=cellular organisms RepID=B1B868_CLOBO
          Length = 99

 Score = 79.6 bits (195), Expect = 3e-13,   Method: Composition-based stats.
 Identities = 29/80 (36%), Positives = 38/80 (47%), Gaps = 9/80 (11%)

Query: 19 HDTDNVAIIVNDNGLKAGTRF-------PDGLELIEHIPQGHKVALLDIPANGEIIRYGE 71
          ++ DNVA  V    L+ G             + L   IP GHK AL  I  N EII+YGE
Sbjct: 9  NEKDNVATTVK--YLRKGEEVVVDVFGDEQKILLNNDIPFGHKFALKSINENEEIIKYGE 66

Query: 72 VIGYAVRAIPRGSWIDESMV 91
           IG A + I +G ++    V
Sbjct: 67 EIGQATKNIKQGDYVHVHNV 86


>UniRef50_B5JYR1 Altronate hydrolase n=1 Tax=Octadecabacter antarcticus 238
          RepID=B5JYR1_9RHOB
          Length = 88

 Score = 79.3 bits (194), Expect = 4e-13,   Method: Composition-based stats.
 Identities = 27/77 (35%), Positives = 39/77 (50%), Gaps = 2/77 (2%)

Query: 16 IKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRYGEVIGY 75
          +K    DNVA +++D      T    G+ + + IP GHKVAL  I A   +I+YG VIG+
Sbjct: 14 LKTQAGDNVATLLDDQL--DCTLISGGMSVDQGIPFGHKVALAPIAAGETVIKYGVVIGH 71

Query: 76 AVRAIPRGSWIDESMVV 92
          A   I  G  +    + 
Sbjct: 72 AKTGIREGEHVHVHNIE 88


>UniRef50_C0D6Q5 Putative uncharacterized protein n=1 Tax=Clostridium
          asparagiforme DSM 15981 RepID=C0D6Q5_9CLOT
          Length = 112

 Score = 79.3 bits (194), Expect = 4e-13,   Method: Composition-based stats.
 Identities = 25/86 (29%), Positives = 40/86 (46%), Gaps = 7/86 (8%)

Query: 14 FYIKVHDTDNVAIIVNDNGLKAGTRFPD-------GLELIEHIPQGHKVALLDIPANGEI 66
           ++++H+ D VA  +   G     R  +        ++  E IP G+K+AL  I     +
Sbjct: 3  RFMRMHEQDMVATALEYTGRGESARVYNPQNELLFEVKAEEDIPFGNKIALTRISKGERV 62

Query: 67 IRYGEVIGYAVRAIPRGSWIDESMVV 92
          I+YG  IG AVR I +G  +    V 
Sbjct: 63 IKYGAPIGVAVRDIQKGRMVHVHNVR 88


>UniRef50_D2QGM2 Putative uncharacterized protein n=1 Tax=Spirosoma linguale DSM 74
           RepID=D2QGM2_9SPHI
          Length = 343

 Score = 78.9 bits (193), Expect = 5e-13,   Method: Composition-based stats.
 Identities = 44/266 (16%), Positives = 80/266 (30%), Gaps = 51/266 (19%)

Query: 110 EPLPPLEGYTFEGYRNADGSVGTKNLLGITTSV--------------------HCVAGVV 149
                 +  +F GY   DG VGT+N   + +                       C     
Sbjct: 17  RAESNRQSLSFMGYYRPDGRVGTRNYWLVISLAPVDPEQMALFQEACQTVLGYQCPNAYE 76

Query: 150 DYVVKIIERDLL-----------------PKYPNVDGVVGLNHLYGCGVAINAPAAVVPI 192
             +  + E+                    P + N+DG+  L          +A A    +
Sbjct: 77  QQLRNLREQYRAGSYFNTPAPQPVRSVPKPVFTNIDGIRFLPV-----YDDSAMALEAVL 131

Query: 193 RTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQ 252
             +     + N GG + V+  G    +   L          P  S  ++ +    +    
Sbjct: 132 DVLAGYCTHANVGG-ITVLSGGATTDRVRALHQCIAKRD--PAFSKPMLVVDRLTYRSDS 188

Query: 253 SMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVR 312
             +        R +  LN++ R + P S LV+  Q G ++       N  V      +  
Sbjct: 189 DWLTAATYDTFRGMALLNKQTRRSAPLSRLVISTQQGKTNES---LPNQVVDECVQFMAS 245

Query: 313 CGATVMFSEV---TEVRDAIHLLTPR 335
            GATV+  +    T++     +   R
Sbjct: 246 VGATVLLVDTNQSTDIHGVQLISETR 271


>UniRef50_B5J029 Putative uncharacterized protein n=1 Tax=Octadecabacter antarcticus
           307 RepID=B5J029_9RHOB
          Length = 122

 Score = 78.5 bits (192), Expect = 6e-13,   Method: Composition-based stats.
 Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 7/117 (5%)

Query: 142 VHCVAGVVDYVVKIIER-DLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISL 200
           ++  A V+      I    LL  Y +VDGVV L H  GCG+A +     +  R +   ++
Sbjct: 1   MNRSATVIRRAASEIAASRLLEDYASVDGVVALAHGTGCGMANSGWGFDILDRVLWGHAI 60

Query: 201 NPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVED 257
           +PN G  V  +GLGCE +Q   + + +              +L  +   G ++ ++ 
Sbjct: 61  HPNVGATV-FVGLGCEVMQIAGMQSHSGTAGTDRFH-----ALTIQDTGGTRATIDA 111


>UniRef50_B8G2E2 SAF domain protein n=2 Tax=Desulfitobacterium hafniense
           RepID=B8G2E2_DESHD
          Length = 103

 Score = 77.7 bits (190), Expect = 9e-13,   Method: Composition-based stats.
 Identities = 28/98 (28%), Positives = 45/98 (45%), Gaps = 10/98 (10%)

Query: 18  VHDTDNVAIIVNDNGLKAGTRF-------PDGLELIEHIPQGHKVALLDIPANGEIIRYG 70
           +++ DNVA  V  + + AGT          + L + + IP GHKVAL+ I  +  +++YG
Sbjct: 8   IYEKDNVATCV--DHIPAGTTISFFRGSQAESLTVCQDIPLGHKVALIPIAQSSHVVKYG 65

Query: 71  EVIGYAVRAIPRGSWIDESMVVLPEA-PPLHTLPLATK 107
           E IG A   I  G  +    +        L T    ++
Sbjct: 66  ESIGAATIDIQPGQHVHVHNMESQRGRGDLDTDKEGSR 103


>UniRef50_C5SG41 SAF domain protein n=1 Tax=Asticcacaulis excentricus CB 48
          RepID=C5SG41_9CAUL
          Length = 102

 Score = 77.7 bits (190), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 26/81 (32%), Positives = 40/81 (49%), Gaps = 5/81 (6%)

Query: 15 YIKVHDTDNVAIIVNDNGLKAGTRFPDGLELI---EHIPQGHKVALLDIPANGEIIRYGE 71
           I +H +DNVA+      + AG+    G E +   E I  GHKVA+ D+ A  +I +YG 
Sbjct: 7  LILLHPSDNVAVC--RAAITAGSVVTVGAEALLITEPIEVGHKVAVRDLNAGDKIFKYGA 64

Query: 72 VIGYAVRAIPRGSWIDESMVV 92
           IG   +  P+G  +    + 
Sbjct: 65 PIGSMTKDTPKGGHVHMHNMK 85


>UniRef50_A1HS78 Hydrolase, UxaA family n=2 Tax=Thermosinus carboxydivorans Nor1
          RepID=A1HS78_9FIRM
          Length = 103

 Score = 77.3 bits (189), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 5/85 (5%)

Query: 13 AFYIKVHDTDNVAIIVN---DNGLKAGTRFPDGLELI--EHIPQGHKVALLDIPANGEII 67
          A  I +   DNV  +V                 + ++  E IP GHK+AL +IPA   II
Sbjct: 2  ARAIIMKAIDNVCTVVETVEPPTEVTAEIDGKTITVLATERIPFGHKIALQNIPAGQPII 61

Query: 68 RYGEVIGYAVRAIPRGSWIDESMVV 92
          +YGE IG A + I  G  +    + 
Sbjct: 62 KYGETIGLATQDIQSGQHVHVHNLE 86


>UniRef50_Q184J3 Probable carbohydrate hydrolase (N-terminus) n=5 Tax=Bacteria
          RepID=Q184J3_CLOD6
          Length = 101

 Score = 76.9 bits (188), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 19/83 (22%), Positives = 36/83 (43%), Gaps = 10/83 (12%)

Query: 18 VHDTDNVAIIVNDNGLKAGTRFP--------DGLELIEHIPQGHKVALLDIPANGEIIRY 69
          + + DNVA+ +    +  G+             +  ++ I   HK+A+ D+    ++ +Y
Sbjct: 7  IDEKDNVAVAIE--AIAKGSEISFKLKDKTVKTITALDDITIYHKLAIKDMAKGDKVTKY 64

Query: 70 GEVIGYAVRAIPRGSWIDESMVV 92
          GE IG A + I  G  +    V 
Sbjct: 65 GEHIGEANQEIKSGQHVHIHNVR 87


>UniRef50_D2RM01 SAF domain protein n=3 Tax=Bacteria RepID=D2RM01_ACIFE
          Length = 100

 Score = 76.9 bits (188), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 25/83 (30%), Positives = 44/83 (53%), Gaps = 9/83 (10%)

Query: 16 IKVHDTDNVAIIVNDNGLKAGTRF-------PDGLELIEHIPQGHKVALLDIPANGEIIR 68
          + + D DNV   V +  +  G +         + +E +E+IP  HK+AL D+P   E+I+
Sbjct: 6  LLMDDRDNVVTCVAE--IHKGEQVVYKKDGREEQVEALENIPFCHKIALTDLPEGSEVIK 63

Query: 69 YGEVIGYAVRAIPRGSWIDESMV 91
          YGE++G     + RG W+ +  +
Sbjct: 64 YGELLGKTNAPVARGHWVSDKNI 86


>UniRef50_C0CW84 Putative uncharacterized protein n=1 Tax=Clostridium
          asparagiforme DSM 15981 RepID=C0CW84_9CLOT
          Length = 96

 Score = 75.4 bits (184), Expect = 5e-12,   Method: Composition-based stats.
 Identities = 29/84 (34%), Positives = 43/84 (51%), Gaps = 9/84 (10%)

Query: 16 IKVHDTDNVAIIVNDNGLKAGTRFPDG--------LELIEHIPQGHKVALLDIPANGEII 67
          +KV D DNVA +    G++AG              +  ++ IP GHKVA+  I    +I+
Sbjct: 5  LKVSDLDNVATVFA-EGIQAGAEIEVRDKKGESVVIRALDPIPYGHKVAVRGIETGEQIM 63

Query: 68 RYGEVIGYAVRAIPRGSWIDESMV 91
          +YGE IG A RAI  G+ +    +
Sbjct: 64 KYGEEIGVASRAIAAGNHVHVHNL 87


>UniRef50_B6BQ17 D-galactarate dehydratase/Altronate n=2 Tax=root
          RepID=B6BQ17_9RICK
          Length = 94

 Score = 75.4 bits (184), Expect = 5e-12,   Method: Composition-based stats.
 Identities = 21/89 (23%), Positives = 37/89 (41%), Gaps = 8/89 (8%)

Query: 12 TAFYIKVHDTDNVAIIVNDNGLKAGT--------RFPDGLELIEHIPQGHKVALLDIPAN 63
              I     DNV ++V +                    ++ ++ IP GHK+A+ D+   
Sbjct: 2  ATDIIIHDKKDNVGVVVIEKITPKQDCACWIMEDDSSTNIQSLDEIPLGHKIAMTDLNEG 61

Query: 64 GEIIRYGEVIGYAVRAIPRGSWIDESMVV 92
            I++YG  IG  V++I +G  +    V 
Sbjct: 62 DTILKYGHDIGKVVKSIKKGEHVHVHNVK 90


>UniRef50_A1WPF7 SAF domain n=4 Tax=Burkholderiales RepID=A1WPF7_VEREI
          Length = 113

 Score = 75.4 bits (184), Expect = 5e-12,   Method: Composition-based stats.
 Identities = 26/101 (25%), Positives = 37/101 (36%), Gaps = 6/101 (5%)

Query: 13  AFYIKVHDTDNVAIIVNDNGLKAGT-----RFPDGLELIEHIPQGHKVALLDIPANGEII 67
              I +H  DNVA  + D      T          +   + I  GHK+ +  IP    ++
Sbjct: 14  PRGIILHTADNVAT-LIDPARDGQTCTLQGEVAGQVIARQDIAFGHKICIAPIPLGANVL 72

Query: 68  RYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKV 108
           +YG+VIG A RAI  G       V    A          + 
Sbjct: 73  KYGQVIGRATRAIAAGEHAHVHNVDSARARGDRQERQEVRP 113


>UniRef50_B3PBS2 Hydrolase, UxaA family n=2 Tax=Proteobacteria RepID=B3PBS2_CELJU
          Length = 115

 Score = 74.2 bits (181), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 26/88 (29%), Positives = 37/88 (42%), Gaps = 3/88 (3%)

Query: 13  AFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIE--HIPQGHKVALLDIPANGEIIRYG 70
           A  I +H TDNV I V+           DG  L+    I  GHKVA L +    +++RYG
Sbjct: 16  ASLILLHPTDNVLICVSPIHAGDAIVI-DGTTLVAPMAISVGHKVARLSMSPGDKVLRYG 74

Query: 71  EVIGYAVRAIPRGSWIDESMVVLPEAPP 98
             IG     + +G  +    +     P 
Sbjct: 75  APIGSITEPVNQGEHVHMHNMKSDYIPS 102


>UniRef50_D2S1L9 SAF domain protein n=1 Tax=Haloterrigena turkmenica DSM 5511
          RepID=D2S1L9_9EURY
          Length = 106

 Score = 74.2 bits (181), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 6/81 (7%)

Query: 18 VHDTDNVAIIVNDNGLKAGTRFPD------GLELIEHIPQGHKVALLDIPANGEIIRYGE 71
          + ++D VA  + D          D       LE+ E I  GHK+A++ I A   + +YGE
Sbjct: 13 LAESDTVATAIADLEAGRSIETDDLPGDRSALEVAEPIAFGHKLAVMAIDAGEPVRKYGE 72

Query: 72 VIGYAVRAIPRGSWIDESMVV 92
          VIG A   I  G W+      
Sbjct: 73 VIGTATERIEPGEWVHIHNCE 93


>UniRef50_B2T9V7 SAF domain protein n=33 Tax=Burkholderia RepID=B2T9V7_BURPP
          Length = 110

 Score = 73.5 bits (179), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 24/90 (26%), Positives = 39/90 (43%), Gaps = 5/90 (5%)

Query: 13 AFYIKVHDTDNVAIIVNDNGLKAGTRFP---DGLELIEHIPQGHKVALLDIPANGEIIRY 69
             I +   DN  I      L  GT+     + + L   I  GHKVA  ++  + +++RY
Sbjct: 12 PRLILLSPADNCLIAAAR--LDCGTQVEIEGERVTLTRTIDLGHKVARHELAKDDKVLRY 69

Query: 70 GEVIGYAVRAIPRGSWIDESMVVLPEAPPL 99
          G VIG+   A+ RG+ +    +     P  
Sbjct: 70 GAVIGHVTEAVARGAHLHTHNLESDYLPTY 99


>UniRef50_D1Y7V9 Mannonate dehydratase n=1 Tax=Pyramidobacter piscolens W5455
           RepID=D1Y7V9_9BACT
          Length = 98

 Score = 73.1 bits (178), Expect = 3e-11,   Method: Composition-based stats.
 Identities = 19/90 (21%), Positives = 32/90 (35%), Gaps = 1/90 (1%)

Query: 15  YIKVHDTDNVAIIVNDNGLKAGTRFPD-GLELIEHIPQGHKVALLDIPANGEIIRYGEVI 73
            I V+  DN+   +          F          IPQ HK+A+ +I       +YGE+I
Sbjct: 4   VIHVNPRDNLVTCLRPVAKGERIEFEGKNYVAAADIPQFHKMAVAEIKKGEHCYKYGEII 63

Query: 74  GYAVRAIPRGSWIDESMVVLPEAPPLHTLP 103
           G A+  +  G ++    +            
Sbjct: 64  GTALTDLHPGDYVHVHNLESTRGRGDRNAE 93


>UniRef50_B8IYJ4 SAF domain protein n=5 Tax=Proteobacteria RepID=B8IYJ4_DESDA
          Length = 94

 Score = 72.3 bits (176), Expect = 4e-11,   Method: Composition-based stats.
 Identities = 19/54 (35%), Positives = 25/54 (46%)

Query: 43 LELIEHIPQGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEA 96
           E +  IP GHK+AL D+     II+Y   IG  V+ I RG  +    V     
Sbjct: 41 FETLSDIPIGHKIALKDLAVGDTIIKYSTDIGKVVKPIKRGEHLHVHNVKTKRW 94


>UniRef50_C9XPT3 Altronate hydrolase (N-terminus) n=4 Tax=Clostridium difficile
          RepID=C9XPT3_CLODC
          Length = 91

 Score = 71.9 bits (175), Expect = 5e-11,   Method: Composition-based stats.
 Identities = 18/82 (21%), Positives = 32/82 (39%), Gaps = 1/82 (1%)

Query: 16 IKVHDTDNVAIIVNDNGLKAGTRFPD-GLELIEHIPQGHKVALLDIPANGEIIRYGEVIG 74
          I  ++ DN+   V                 + ++IP  HK+A  D+     + +YGE+IG
Sbjct: 5  IHANEKDNLVTCVRPLVKGEKVSIDGKSYIVNDNIPVFHKMATEDVKKGDVVYKYGEIIG 64

Query: 75 YAVRAIPRGSWIDESMVVLPEA 96
           A   I  G ++    +     
Sbjct: 65 IATVDIKTGDYVHVHNIESTRG 86


>UniRef50_A4GAA3 Altronate dehydratase (N part) n=3 Tax=Proteobacteria
          RepID=A4GAA3_HERAR
          Length = 93

 Score = 70.0 bits (170), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 22/91 (24%), Positives = 35/91 (38%), Gaps = 10/91 (10%)

Query: 15 YIKVHDTDNVAIIVNDNGLKAGTRFPD---------GLELIEHIPQGHKVALLDIPANGE 65
           +     D VA+ V   G+KAGT              ++ ++ IP GHK+A+  +     
Sbjct: 4  VVLHDAKDTVAVAVV-EGIKAGTDLTAWIMDDDRTVSIKALQDIPMGHKIAMKPMAVGDT 62

Query: 66 IIRYGEVIGYAVRAIPRGSWIDESMVVLPEA 96
          + +YG  IG  V A   G       +     
Sbjct: 63 VFKYGVDIGKVVAAAKAGEHAHVHNIKTKRW 93


>UniRef50_B0PEC9 Putative uncharacterized protein n=1 Tax=Anaerotruncus
          colihominis DSM 17241 RepID=B0PEC9_9FIRM
          Length = 103

 Score = 69.6 bits (169), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 9/87 (10%)

Query: 13 AFYIKVHDTDNVAIIVNDNGLKAGTRFP-------DGLELIEHIPQGHKVALLDIPANGE 65
          A  I +   DNV  +V  +G K G           + L   E IP  HK A+  I   G 
Sbjct: 3  ANAILLSTKDNVVTVV--DGAKQGEEIRYFANGELESLIARETIPPCHKAAIAPIEPGGH 60

Query: 66 IIRYGEVIGYAVRAIPRGSWIDESMVV 92
          +++YGE IG A R I  G W+    + 
Sbjct: 61 VLKYGESIGAATRPIGVGEWVSHLNIE 87


>UniRef50_Q1QWP1 D-galactarate dehydratase/Altronate hydrolase-like protein n=6
          Tax=Proteobacteria RepID=Q1QWP1_CHRSD
          Length = 94

 Score = 69.2 bits (168), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 16/54 (29%), Positives = 28/54 (51%)

Query: 43 LELIEHIPQGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEA 96
           E+ + IP GHK+A+ D+  +  +I+Y   IG  V++I +G  +    V     
Sbjct: 41 FEVKDAIPIGHKLAIRDLAEDETVIKYSVDIGRVVQSIRQGEHVHVHNVKTKRW 94


>UniRef50_B8DQ83 D-galactarate dehydratase/altronate hydrolase-like protein n=5
          Tax=Proteobacteria RepID=B8DQ83_DESVM
          Length = 94

 Score = 69.2 bits (168), Expect = 4e-10,   Method: Composition-based stats.
 Identities = 16/55 (29%), Positives = 26/55 (47%)

Query: 42 GLELIEHIPQGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEA 96
            +++  IP GHK+AL D+     +++YG  IG  V  I +G  +    V     
Sbjct: 40 TFKVLNDIPIGHKLALNDLSVGDTVMKYGTDIGKVVAPIKQGEHLHVHNVKTKRW 94


>UniRef50_Q2G5K6 D-galactarate dehydratase/Altronate hydrolase-like protein n=1
          Tax=Novosphingobium aromaticivorans DSM 12444
          RepID=Q2G5K6_NOVAD
          Length = 109

 Score = 69.2 bits (168), Expect = 4e-10,   Method: Composition-based stats.
 Identities = 14/78 (17%), Positives = 29/78 (37%), Gaps = 1/78 (1%)

Query: 15 YIKVHDTDNVAIIVNDNGLKAGTRFPD-GLELIEHIPQGHKVALLDIPANGEIIRYGEVI 73
          ++ +   DN+ +   D             + L + +  GHK+A   + A  +++RYG  I
Sbjct: 13 FLLLDPADNILVCTRDALAGDLVTIDGIHVRLPQPVGVGHKIARRPLAAGEKVLRYGAPI 72

Query: 74 GYAVRAIPRGSWIDESMV 91
          G           +    +
Sbjct: 73 GSMTADAAIAEHVHSHNL 90


>UniRef50_Q1ASX0 Altronate hydrolase n=1 Tax=Rubrobacter xylanophilus DSM 9941
           RepID=Q1ASX0_RUBXD
          Length = 107

 Score = 67.7 bits (164), Expect = 1e-09,   Method: Composition-based stats.
 Identities = 26/106 (24%), Positives = 41/106 (38%), Gaps = 13/106 (12%)

Query: 4   IEIRQETPTAFYIKVHD------TDNVAIIVNDNGLKA---GTRFPDG----LELIEHIP 50
           I+IR+  P +    +H        D+V +  +D        G    DG    +   E +P
Sbjct: 2   IQIRKILPISRRAGLHKFLIHRRGDHVGVATSDIARGERVVGVYMDDGSAVEVVAREEVP 61

Query: 51  QGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEA 96
            GHK+A+      GE+I YG  IG A      G ++    +     
Sbjct: 62  LGHKIAVERCEPGGEVIEYGVRIGLAPEGFEAGDYVHTHNLKSARW 107


>UniRef50_B0T1B9 D-galactarate dehydratase/altronate hydrolase-like protein n=1
          Tax=Caulobacter sp. K31 RepID=B0T1B9_CAUSK
          Length = 98

 Score = 66.9 bits (162), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 15/79 (18%), Positives = 31/79 (39%), Gaps = 1/79 (1%)

Query: 15 YIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIE-HIPQGHKVALLDIPANGEIIRYGEVI 73
           I +H  DNV ++                 + +  +  GHK+A  D+    ++++YG  I
Sbjct: 3  LILLHPDDNVLVLSAPVRAGQVLTIDGRTAVADADVGTGHKLARHDLAIGDKVLKYGAPI 62

Query: 74 GYAVRAIPRGSWIDESMVV 92
          G    ++  G  +    + 
Sbjct: 63 GSITASVAAGGHVHLHNMK 81


>UniRef50_Q0RXW3 Putative uncharacterized protein n=1 Tax=Rhodococcus jostii RHA1
           RepID=Q0RXW3_RHOSR
          Length = 333

 Score = 64.2 bits (155), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 20/83 (24%), Positives = 35/83 (42%), Gaps = 8/83 (9%)

Query: 6   IRQETPTAFYIKVHDTDNVAIIVNDNGLKA------GTRFPDGLELIEHIPQGHKVALLD 59
           +  ++P    +   D D VA+   D            +   + ++L + +P GHK+AL D
Sbjct: 179 MSNQSP--DLLAHSDGDAVAVGARDLSTGPVPVEDLESTQTEHVDLADAVPLGHKLALRD 236

Query: 60  IPANGEIIRYGEVIGYAVRAIPR 82
           +     +I YG  +G A    P 
Sbjct: 237 VAEGEPVIDYGLAVGAATTDTPA 259


>UniRef50_B0K1I8 SAF domain n=9 Tax=Thermoanaerobacterales RepID=B0K1I8_THEPX
          Length = 96

 Score = 64.2 bits (155), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 20/85 (23%), Positives = 41/85 (48%), Gaps = 10/85 (11%)

Query: 16 IKVHDTDNVAIIVNDNGLKAGTRFP--------DGLELIEHIPQGHKVALLDIPANGEII 67
          I ++  D+VA  ++   ++ G            + L  ++ I   HK+A++ I +   + 
Sbjct: 8  ILLNKADSVATALSQ--IQKGDVVDIIYNNETVNRLIALDDIEIYHKIAVVPIQSGNNVY 65

Query: 68 RYGEVIGYAVRAIPRGSWIDESMVV 92
          +YGEVIG A+++I  G  +    + 
Sbjct: 66 KYGEVIGKAIKSIEIGQCVHIDNIE 90


>UniRef50_C0CYJ4 Putative uncharacterized protein n=1 Tax=Clostridium
          asparagiforme DSM 15981 RepID=C0CYJ4_9CLOT
          Length = 101

 Score = 64.2 bits (155), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 5/82 (6%)

Query: 16 IKVHDTDNVAIIVNDNGLKAGTRFPDG-----LELIEHIPQGHKVALLDIPANGEIIRYG 70
          + + +TDNV   V +        +  G     +E +E IP  HK+AL+      E+++YG
Sbjct: 9  LMMEETDNVVTCVMEIKKGDAVVYRKGDTYCTVEALEDIPYCHKIALIPFDEGDEVVKYG 68

Query: 71 EVIGYAVRAIPRGSWIDESMVV 92
          E+IG   RAI +G  ++   + 
Sbjct: 69 EMIGRTNRAIGKGCLVNHENIY 90


>UniRef50_D1U489 SAF domain protein n=1 Tax=Desulfovibrio aespoeensis Aspo-2
          RepID=D1U489_9DELT
          Length = 99

 Score = 63.8 bits (154), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 9/85 (10%)

Query: 15 YIKVHDTDNVAIIVNDNGLKAGTRFP-------DGLELIEHIPQGHKVALLDIPANGEII 67
           I +   DNV   + D  +  G                ++ IP G K A+ DIPA+G+II
Sbjct: 4  LIVMSAEDNVGNAIED--IVGGDEVSYTVGGKVHTFTAVDEIPFGFKAAVKDIPASGDII 61

Query: 68 RYGEVIGYAVRAIPRGSWIDESMVV 92
          +Y EV+G A R I  G  +    V 
Sbjct: 62 KYKEVVGQAGRDIRAGECVHIHNVE 86


>UniRef50_A8H9C9 D-galactarate dehydratase n=4 Tax=Proteobacteria
          RepID=A8H9C9_SHEPA
          Length = 111

 Score = 63.5 bits (153), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 7/89 (7%)

Query: 16 IKVHDTDNVAIIVNDNG-------LKAGTRFPDGLELIEHIPQGHKVALLDIPANGEIIR 68
          I++   DNVA ++ D         +    +  D +  ++ I  G+KVAL DI A   I +
Sbjct: 5  IQLDPADNVATLLVDAVKGDEIEIISTNNQVIDLVTCLQAITFGNKVALTDIAAQQLITK 64

Query: 69 YGEVIGYAVRAIPRGSWIDESMVVLPEAP 97
              +G A++AIPRG       V      
Sbjct: 65 ASYPVGVAIKAIPRGELAHVQNVRSQRLD 93


>UniRef50_Q58Y44 Sulfolactate sulfo-lyase small subunit n=1 Tax=Paracoccus
          pantotrophus RepID=Q58Y44_PARPN
          Length = 67

 Score = 63.5 bits (153), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 17/54 (31%), Positives = 21/54 (38%)

Query: 43 LELIEHIPQGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEA 96
          L     IP GHKVAL  + A   +I+Y E IG  V     G  +          
Sbjct: 14 LTAKADIPIGHKVALKALKAGDTVIKYHEDIGKMVGDAEVGGHVHTHNCKTKRW 67


>UniRef50_B5J028 Putative uncharacterized protein n=1 Tax=Octadecabacter antarcticus
           307 RepID=B5J028_9RHOB
          Length = 61

 Score = 51.9 bits (123), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 14/60 (23%), Positives = 23/60 (38%), Gaps = 1/60 (1%)

Query: 67  IRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPE-PLPPLEGYTFEGYRN 125
           I++G+ IG A  AI  G  +     V       + +       +  +P  +  TF GY  
Sbjct: 2   IKFGQFIGQATVAIAAGDHVHTHNCVFANPEKDYAIGADLAAAQRAIPHTDLLTFSGYAR 61


>UniRef50_Q4HS65 Putative uncharacterized protein n=1 Tax=Campylobacter upsaliensis
           RM3195 RepID=Q4HS65_CAMUP
          Length = 61

 Score = 48.8 bits (115), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 14/30 (46%), Positives = 17/30 (56%)

Query: 425 QQVASGITVQVFTTGRGTPYGLMAVPVIKM 454
             VA G  + VFTTGRG   G + V  IK+
Sbjct: 29  AMVAGGANICVFTTGRGMLTGSVIVLTIKI 58


Searching..................................................done


Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_P39829 D-galactarate dehydratase n=231 Tax=cellular org...   628   e-178
UniRef50_A5FZN2 Galactarate dehydratase n=111 Tax=Bacteria RepID...   613   e-174
UniRef50_C1ZG32 Altronate dehydratase n=1 Tax=Planctomyces limno...   611   e-173
UniRef50_D2QZ01 Altronate dehydratase n=1 Tax=Pirellula staleyi ...   599   e-170
UniRef50_A6W5I2 Altronate dehydratase n=32 Tax=Bacteria RepID=A6...   598   e-169
UniRef50_C4X086 Altronate hydrolase n=14 Tax=Bacteria RepID=C4X0...   595   e-168
UniRef50_A6VSK2 Altronate dehydratase n=7 Tax=Proteobacteria Rep...   590   e-167
UniRef50_P42604 Altronate hydrolase n=77 Tax=Bacteria RepID=UXAA...   590   e-167
UniRef50_Q21ZN4 Galactarate dehydratase n=8 Tax=Proteobacteria R...   586   e-166
UniRef50_Q028V7 Altronate dehydratase n=1 Tax=Candidatus Solibac...   583   e-165
UniRef50_O34673 Altronate hydrolase n=80 Tax=Bacteria RepID=UXAA...   582   e-165
UniRef50_A9KNI4 Altronate dehydratase n=3 Tax=Clostridiales RepI...   582   e-164
UniRef50_D0D8F8 D-galactarate dehydratase n=2 Tax=Rhodobacterace...   578   e-163
UniRef50_D1BWK3 Galactarate dehydratase n=1 Tax=Xylanimonas cell...   575   e-162
UniRef50_D0ZBA7 Altronate hydrolase n=15 Tax=Bacteria RepID=D0ZB...   575   e-162
UniRef50_A7Z3M9 UxaA n=20 Tax=Bacteria RepID=A7Z3M9_BACA2             569   e-161
UniRef50_A0RPU2 Altronate hydrolase n=10 Tax=Bacteria RepID=A0RP...   568   e-160
UniRef50_Q7UKI4 Altronate hydrolase n=2 Tax=Planctomycetales Rep...   567   e-160
UniRef50_C9B1P2 Altronate dehydratase n=9 Tax=Bacteria RepID=C9B...   565   e-159
UniRef50_D2QEC5 Altronate dehydratase n=2 Tax=Sphingobacteriales...   560   e-158
UniRef50_A0M231 Altronate hydrolase n=9 Tax=Bacteria RepID=A0M23...   559   e-157
UniRef50_C5SJY8 Altronate dehydratase n=3 Tax=Proteobacteria Rep...   555   e-156
UniRef50_C4STJ6 Altronate dehydratase n=1 Tax=Yersinia frederiks...   551   e-155
UniRef50_B0T3J7 Altronate dehydratase n=15 Tax=Bacteria RepID=B0...   550   e-155
UniRef50_C1NB77 Altronate dehydratase n=2 Tax=Enterobacteriaceae...   549   e-155
UniRef50_UPI0001C34772 Altronate dehydratase n=1 Tax=Providencia...   546   e-153
UniRef50_C6J327 Altronate dehydratase n=1 Tax=Paenibacillus sp. ...   541   e-152
UniRef50_C7PV23 Altronate dehydratase n=13 Tax=Bacteria RepID=C7...   540   e-152
UniRef50_B5FMP6 Hydrolase, UxaA family n=75 Tax=cellular organis...   483   e-135
UniRef50_B0K1I9 Altronate dehydratase n=10 Tax=Firmicutes RepID=...   468   e-130
UniRef50_Q5WIY9 Altronate hydrolase C-terminus n=5 Tax=Firmicute...   462   e-128
UniRef50_Q6L323 Altronate hydrolase n=1 Tax=Picrophilus torridus...   457   e-127
UniRef50_C0CW83 Putative uncharacterized protein n=1 Tax=Clostri...   445   e-123
UniRef50_Q1AYL8 D-galactarate dehydratase/Altronate hydrolase-li...   443   e-123
UniRef50_D1Y193 Galactarate dehydratase n=1 Tax=Pyramidobacter p...   438   e-121
UniRef50_D1Y174 D-galactarate dehydratase (GalcD) n=3 Tax=Bacter...   431   e-119
UniRef50_D2PZR0 D-galactarate dehydratase/Altronate hydrolase do...   429   e-118
UniRef50_A9V9F3 Predicted protein n=1 Tax=Monosiga brevicollis R...   427   e-118
UniRef50_A8RT57 Putative uncharacterized protein n=1 Tax=Clostri...   415   e-114
UniRef50_B8FML6 Altronate dehydratase n=1 Tax=Desulfatibacillum ...   408   e-112
UniRef50_C5EFV8 Hydrolase n=1 Tax=Clostridiales bacterium 1_7_47...   405   e-111
UniRef50_B5IW17 D-galactarate dehydratase / Altronate hydrolase,...   404   e-111
UniRef50_D2S1M0 Altronate dehydratase n=1 Tax=Haloterrigena turk...   402   e-110
UniRef50_B1M8U1 Altronate dehydratase n=55 Tax=root RepID=B1M8U1...   402   e-110
UniRef50_Q13SA4 Altronate dehydratase n=48 Tax=Bacteria RepID=Q1...   402   e-110
UniRef50_C9KKM7 Hydrolase, UxaA family n=1 Tax=Mitsuokella multa...   400   e-110
UniRef50_Q0KC73 D-Galactarate dehydratase n=4 Tax=Burkholderiale...   397   e-109
UniRef50_C5EF38 Altronate dehydratase n=2 Tax=Clostridiales RepI...   393   e-107
UniRef50_A7VSH2 Putative uncharacterized protein n=1 Tax=Clostri...   385   e-105
UniRef50_B6WWW3 Putative uncharacterized protein n=2 Tax=Desulfo...   383   e-104
UniRef50_A8H9C8 D-galactarate dehydratase/Altronate hydrolase do...   347   7e-94
UniRef50_D0Z3R7 Altronate hydrolase n=2 Tax=Bacteria RepID=D0Z3R...   336   9e-91
UniRef50_B5JYR2 D-Galactarate dehydratase n=1 Tax=Octadecabacter...   330   7e-89
UniRef50_D2S1L8 Altronate dehydratase-like protein n=1 Tax=Halot...   281   5e-74
UniRef50_C8T5I2 D-galactarate dehydratase n=3 Tax=Enterobacteria...   200   1e-49
UniRef50_B7DPM4 Altronate dehydratase n=1 Tax=Alicyclobacillus a...   195   4e-48
UniRef50_B9TLG0 Putative uncharacterized protein (Fragment) n=1 ...   173   1e-41
UniRef50_D2QGM2 Putative uncharacterized protein n=1 Tax=Spiroso...   156   2e-36
UniRef50_UPI00017F2C45 Altronate dehydratase n=2 Tax=Enterobacte...   138   5e-31
UniRef50_UPI00017F3110 galactarate dehydratase n=1 Tax=Escherich...   114   7e-24
UniRef50_A8MAM1 SAF domain protein n=5 Tax=cellular organisms Re...   113   2e-23
UniRef50_B4D086 SAF domain protein n=1 Tax=Chthoniobacter flavus...   109   4e-22
UniRef50_D2PG65 SAF domain protein n=15 Tax=cellular organisms R...   105   4e-21
UniRef50_D2NF82 Truncated altronate dehydratase n=2 Tax=Escheric...   103   2e-20
UniRef50_C8ZXV8 D-galactarate dehydratase n=1 Tax=Enterococcus g...   102   3e-20
UniRef50_Q5WIZ0 Altronate hydrolase N-terminus n=5 Tax=Bacteria ...   102   4e-20
UniRef50_A7VSH3 Putative uncharacterized protein n=1 Tax=Clostri...   102   4e-20
UniRef50_Q0RXU4 Possible sulfolactate sulfo-lyase small subunit ...   101   5e-20
UniRef50_B8FML5 SAF domain protein n=1 Tax=Desulfatibacillum alk...   101   5e-20
UniRef50_C5EFR7 Predicted protein n=1 Tax=Clostridiales bacteriu...   101   6e-20
UniRef50_Q6L322 Altronate hydrolase n=1 Tax=Picrophilus torridus...   101   1e-19
UniRef50_Q3ACL1 Hydrolase, UxaA family n=1 Tax=Carboxydothermus ...   100   3e-19
UniRef50_B5J029 Putative uncharacterized protein n=1 Tax=Octadec...    99   4e-19
UniRef50_Q9HIE8 Putative uncharacterized protein Ta1392 n=1 Tax=...    99   4e-19
UniRef50_A1WPF7 SAF domain n=4 Tax=Burkholderiales RepID=A1WPF7_...    99   4e-19
UniRef50_D1Y7V9 Mannonate dehydratase n=1 Tax=Pyramidobacter pis...    99   5e-19
UniRef50_C1XHK9 Altronate dehydratase n=2 Tax=Meiothermus RepID=...    99   5e-19
UniRef50_B8IQB2 SAF domain protein n=8 Tax=Proteobacteria RepID=...    98   5e-19
UniRef50_C0GPG6 SAF domain protein n=1 Tax=Desulfonatronospira t...    98   7e-19
UniRef50_B8FVM2 SAF domain protein n=4 Tax=Desulfitobacterium ha...    98   9e-19
UniRef50_B1B868 Altronate hydrolase n=7 Tax=cellular organisms R...    98   9e-19
UniRef50_B8G2E2 SAF domain protein n=2 Tax=Desulfitobacterium ha...    98   1e-18
UniRef50_C9XPT3 Altronate hydrolase (N-terminus) n=4 Tax=Clostri...    97   1e-18
UniRef50_Q184J3 Probable carbohydrate hydrolase (N-terminus) n=5...    97   1e-18
UniRef50_B3PBS2 Hydrolase, UxaA family n=2 Tax=Proteobacteria Re...    97   2e-18
UniRef50_B4TB53 Hydrolase, UxaA family n=14 Tax=Bacteria RepID=B...    97   2e-18
UniRef50_C0D6Q5 Putative uncharacterized protein n=1 Tax=Clostri...    97   2e-18
UniRef50_C5SG41 SAF domain protein n=1 Tax=Asticcacaulis excentr...    96   3e-18
UniRef50_B6BQ17 D-galactarate dehydratase/Altronate n=2 Tax=root...    96   3e-18
UniRef50_D1Y192 Mannonate dehydratase n=1 Tax=Pyramidobacter pis...    96   3e-18
UniRef50_C3WAI6 Carbohydrate hydrolase n=2 Tax=Bacteria RepID=C3...    95   5e-18
UniRef50_D2RM01 SAF domain protein n=3 Tax=Bacteria RepID=D2RM01...    94   1e-17
UniRef50_C5EF39 Altronate hydrolase n=3 Tax=Clostridiales RepID=...    93   2e-17
UniRef50_A1HS78 Hydrolase, UxaA family n=2 Tax=Thermosinus carbo...    93   3e-17
UniRef50_B5JYR1 Altronate hydrolase n=1 Tax=Octadecabacter antar...    92   4e-17
UniRef50_B2T9V7 SAF domain protein n=33 Tax=Burkholderia RepID=B...    91   8e-17
UniRef50_C2DK38 Putative uncharacterized protein n=2 Tax=Escheri...    90   1e-16
UniRef50_D2S1L9 SAF domain protein n=1 Tax=Haloterrigena turkmen...    89   4e-16
UniRef50_Q1ASX0 Altronate hydrolase n=1 Tax=Rubrobacter xylanoph...    88   8e-16
UniRef50_Q2G5K6 D-galactarate dehydratase/Altronate hydrolase-li...    88   1e-15
UniRef50_A4GAA3 Altronate dehydratase (N part) n=3 Tax=Proteobac...    88   1e-15
UniRef50_C0CW84 Putative uncharacterized protein n=1 Tax=Clostri...    87   1e-15
UniRef50_C0CYJ4 Putative uncharacterized protein n=1 Tax=Clostri...    87   1e-15
UniRef50_B0PEC9 Putative uncharacterized protein n=1 Tax=Anaerot...    87   1e-15
UniRef50_B0K1I8 SAF domain n=9 Tax=Thermoanaerobacterales RepID=...    86   3e-15
UniRef50_B0T1B9 D-galactarate dehydratase/altronate hydrolase-li...    86   3e-15
UniRef50_B9MJB7 SMP-30/Gluconolaconase/LRE domain protein n=1 Ta...    85   8e-15
UniRef50_B8IYJ4 SAF domain protein n=5 Tax=Proteobacteria RepID=...    83   3e-14
UniRef50_D1U489 SAF domain protein n=1 Tax=Desulfovibrio aespoee...    82   4e-14
UniRef50_B8DQ83 D-galactarate dehydratase/altronate hydrolase-li...    81   1e-13
UniRef50_Q1QWP1 D-galactarate dehydratase/Altronate hydrolase-li...    81   1e-13
UniRef50_A8H9C9 D-galactarate dehydratase n=4 Tax=Proteobacteria...    81   1e-13
UniRef50_Q58Y44 Sulfolactate sulfo-lyase small subunit n=1 Tax=P...    80   2e-13
UniRef50_Q0RXW3 Putative uncharacterized protein n=1 Tax=Rhodoco...    75   5e-12
UniRef50_B5J028 Putative uncharacterized protein n=1 Tax=Octadec...    59   5e-07

Sequences not found previously or not previously below threshold:

UniRef50_Q4HS65 Putative uncharacterized protein n=1 Tax=Campylo...    46   0.003


CONVERGED!
>UniRef50_P39829 D-galactarate dehydratase n=231 Tax=cellular organisms
           RepID=GARD_ECOLI
          Length = 523

 Score =  628 bits (1620), Expect = e-178,   Method: Composition-based stats.
 Identities = 523/523 (100%), Positives = 523/523 (100%)

Query: 1   MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDI 60
           MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDI
Sbjct: 1   MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDI 60

Query: 61  PANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTF 120
           PANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTF
Sbjct: 61  PANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTF 120

Query: 121 EGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCG 180
           EGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCG
Sbjct: 121 EGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCG 180

Query: 181 VAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASI 240
           VAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASI
Sbjct: 181 VAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASI 240

Query: 241 VSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTAN 300
           VSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTAN
Sbjct: 241 VSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTAN 300

Query: 301 PAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGK 360
           PAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGK
Sbjct: 301 PAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGK 360

Query: 361 TDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDF 420
           TDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDF
Sbjct: 361 TDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDF 420

Query: 421 VCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEE 480
           VCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEE
Sbjct: 421 VCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEE 480

Query: 481 TIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAPVT 523
           TIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAPVT
Sbjct: 481 TIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAPVT 523


>UniRef50_A5FZN2 Galactarate dehydratase n=111 Tax=Bacteria RepID=A5FZN2_ACICJ
          Length = 538

 Score =  613 bits (1582), Expect = e-174,   Method: Composition-based stats.
 Identities = 192/521 (36%), Positives = 279/521 (53%), Gaps = 18/521 (3%)

Query: 7   RQETP---TAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDIPAN 63
           R  T        ++++D DNV + +       G    +GL     IP+GHK+A   I A 
Sbjct: 30  RNGTRPMNAPTTVRLNDADNVLVAIEPIASGTG--VAEGLVTSARIPRGHKIASAPIEAG 87

Query: 64  GEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGY 123
             + ++G++IG+A  AI  G+W+ E  V + E    +TL     V     P    TF G+
Sbjct: 88  APVRKFGQIIGFAKEAIAPGAWVHEHNVEVHEFARDYTLGEVKPVEPAAAP---ATFMGF 144

Query: 124 RNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIER-DLLPKYPNVDGVVGLNHLYGCGVA 182
           R A+G VGT+N + I +SV+C A V   +    ER  LL  +PNVDG+V L H  GCG+A
Sbjct: 145 RRANGQVGTRNYIAILSSVNCAATVARQIALRAERSGLLDGFPNVDGIVPLTHGTGCGMA 204

Query: 183 INAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVS 242
            +     +  RT+   + NPN  G V+ IGLGCE LQ  R+                   
Sbjct: 205 ADGEGYELLERTLWGAACNPNVAG-VLFIGLGCEVLQIARMTARYGLKDDPRFH-----W 258

Query: 243 LQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPA 302
           +  +   G  + +E  L      L + +  +RE  PAS L++ +QCGGSDA+SG+TANPA
Sbjct: 259 MTIQDSGGTPATIEAGLAALREILPRADAARREPLPASHLILALQCGGSDAYSGLTANPA 318

Query: 303 VGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTD 362
           +G A+D+LVR G T + SE  E+  A HLL  RA +  V   LL  ++W+ +YL      
Sbjct: 319 LGEAADILVRHGGTAILSETPEIYGAEHLLVHRAASRRVADDLLARIDWWRDYLARTGGQ 378

Query: 363 RSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVC 422
            + NPSPGNK GGL  ++EK+LG++AK G + +  V    +  T+RG ++  TP  D V 
Sbjct: 379 MNNNPSPGNKAGGLTTILEKSLGAVAKGGTTPLTAVYRYAEPVTERGFVFMDTPGYDPVS 438

Query: 423 GTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETI 482
            T QVA G  +  FTTGRG+ +G   VP IK+AT ++L  R    MDI+ G I +G  TI
Sbjct: 439 VTGQVAGGANILCFTTGRGSAFGCKPVPSIKLATNSDLYRRMETDMDIDCGDILSG-TTI 497

Query: 483 EEVGWKLFHFILDVASGKKKTFSDQWGLHN-QLAVFNPAPV 522
            + G ++F  +LDVASG + T S++ G  + +   +    V
Sbjct: 498 AQKGEEIFRHLLDVASGAR-TKSERLGYGDNEFVPWQVGAV 537


>UniRef50_C1ZG32 Altronate dehydratase n=1 Tax=Planctomyces limnophilus DSM 3776
           RepID=C1ZG32_PLALI
          Length = 526

 Score =  611 bits (1577), Expect = e-173,   Method: Composition-based stats.
 Identities = 185/526 (35%), Positives = 276/526 (52%), Gaps = 16/526 (3%)

Query: 10  TPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRY 69
           +     +++   D+VA+   +    + T     L + + +  GHKVALL I A   I++Y
Sbjct: 3   SEPPRLLQLSPVDHVAVATQNLPAGSVTHEGQELLIRQPVRAGHKVALLPIAAGTPILKY 62

Query: 70  GEVIGYAVRAIPRGSWIDESMVV-------LPEAPPLHTLPLATKVPEPLPPLEG-YTFE 121
           G+    A R I  G  +    V           A P        +   P   +E   TF 
Sbjct: 63  GQPFAIASRDILAGEHVHTHNVRVMGPEDCQQLAKPNSASSSHDRSTSPTTHVENEMTFA 122

Query: 122 GYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGV 181
           G R  DG V T+N + +  +V+C + VV  +V+ I +DLL +Y NVDGV+ L H  GC +
Sbjct: 123 GIRRPDGRVATRNYVAVIGTVNCSSTVVRKIVRAISQDLLNQYENVDGVIPLVHSGGCAM 182

Query: 182 AINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIP----VES 237
                      R +   + +PN G  ++V GLGCE  Q   L+     VQ        +S
Sbjct: 183 EFGGTDHRQLARILGGYARHPNIGAYLLV-GLGCETGQGSFLIEQEGLVQLRRSGEVQQS 241

Query: 238 ASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGV 297
           A  + +  ++  G +  +E  L   +  L + N+ QRE+ PASELV+G++CGGSD FSG+
Sbjct: 242 APPLLVNIQEAGGVRRTIERALAALKELLPEANKCQRESIPASELVMGLKCGGSDGFSGL 301

Query: 298 TANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLN 357
           TANPA+G ASDLL+  G T + +E  E+    HLL  R+++ EV ++LL+++ W+  Y  
Sbjct: 302 TANPALGVASDLLISQGGTALLAETPEIFGGEHLLASRSIDSEVSQKLLDKVAWWRAYAA 361

Query: 358 MGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPA 417
              T    NPS GNK+GGL  +VEK+LG+I K G S +V+VL   +R   RGL +  +P 
Sbjct: 362 KFGTTLDGNPSFGNKEGGLTTIVEKSLGAITKGGASPLVDVLDYAERVRHRGLNFMDSPG 421

Query: 418 SDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIAT 477
            D    T  +ASG  V  FTTGRG+ +G    P +K++T T L  R  + MD +AG + +
Sbjct: 422 YDPASVTGLIASGAHVVCFTTGRGSCFGSKPAPTLKISTNTSLFERLSEEMDFDAGRVLS 481

Query: 478 GEETIEEVGWKLFHFILDVASGKKKTFSDQWGLH-NQLAVFNPAPV 522
           G  +I + G  L   +L VASG+K T S+Q G   ++   + P PV
Sbjct: 482 G-ASISQTGQNLLRKVLKVASGEK-TCSEQQGFGDDEFFPWTPGPV 525


>UniRef50_D2QZ01 Altronate dehydratase n=1 Tax=Pirellula staleyi DSM 6068
           RepID=D2QZ01_9PLAN
          Length = 516

 Score =  599 bits (1545), Expect = e-170,   Method: Composition-based stats.
 Identities = 184/513 (35%), Positives = 269/513 (52%), Gaps = 7/513 (1%)

Query: 11  PTAFYIKVHDTDNVAIIVNDNGLKAGTRFP-DGLELIEHIPQGHKVALLDIPANGEIIRY 69
            T   I +H +DN+ +                 + L   I  GHK+A+  I     + +Y
Sbjct: 7   RTTPAIYLHPSDNICVAARTLDAGLKLDIAATTITLSSLIKIGHKIAIAPIAKGSFVYKY 66

Query: 70  GEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGS 129
           G++IG A   I  G  +      L     +     +  +P  LPP+   TF GYR ADG 
Sbjct: 67  GQIIGTATCDIAPGDHVHSHN--LTNGDFVRDYAKSQAIPAALPPITDRTFLGYRRADGK 124

Query: 130 VGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAV 189
            GT+N + + ++V+C A V  Y+    ++ +L  YP++DGV+ L H  GCG+        
Sbjct: 125 AGTRNYIAVISTVNCSASVSKYIANRFDQSILKDYPSIDGVIALKHGGGCGLQYGGLQHQ 184

Query: 190 VPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHV 249
           +  RT+  ++ +PN GG  ++IGLGCE      LL     +Q    +      L  +   
Sbjct: 185 ILARTLGGMAKHPNIGGF-LLIGLGCENAPMGYLLDSQKLIQIDGNKRNMPPVLSMQDLG 243

Query: 250 GFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDL 309
           G    VE  +++    L K    +R   PASE+++G  CGGSD  SGVT NPA+G ASDL
Sbjct: 244 GTAKTVEAGIRMLGELLPKAADVKRVPIPASEIILGTNCGGSDGNSGVTCNPALGVASDL 303

Query: 310 LVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSP 369
           LVRCG T   +E TE+  A HLLT RA   EV  +LLE ++W+  +  M   +   NPS 
Sbjct: 304 LVRCGGTTALAETTEIYGAEHLLTRRARTPEVADKLLERIDWWLWHTKMYGVEIDNNPSV 363

Query: 370 GNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVAS 429
           GNK+GGL  + EK+LG++AK+G +A+ EV    +  T +G +   TP  D    T  VA 
Sbjct: 364 GNKEGGLTTIAEKSLGAVAKTGTTALEEVYHYAEPMTAKGFVVMDTPGFDPPSVTGLVAG 423

Query: 430 GITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKL 489
           G  V VFTTGRG+ +G   VP IK+A+ T +  R  D MDIN+G +  G +++E  G ++
Sbjct: 424 GANVVVFTTGRGSCFGCKPVPSIKVASNTPMYERMIDDMDINSGEVLHG-QSLEAAGQEI 482

Query: 490 FHFILDVASGKKKTFSDQWGLHN-QLAVFNPAP 521
           F  IL VASG+K T S+Q G+ + +   +   P
Sbjct: 483 FEKILSVASGEK-TKSEQHGIGDEEFVPWQVGP 514


>UniRef50_A6W5I2 Altronate dehydratase n=32 Tax=Bacteria RepID=A6W5I2_KINRD
          Length = 533

 Score =  598 bits (1541), Expect = e-169,   Method: Composition-based stats.
 Identities = 192/531 (36%), Positives = 275/531 (51%), Gaps = 28/531 (5%)

Query: 11  PTAFYIKVHDTDNVAIIVNDNGLKAGTRFP-------DGLELIEHIPQGHKVALLDIPAN 63
             A  +++   D VA+      L AGT            L +   +P GHKVAL D+ A 
Sbjct: 11  TAAPLLRLAPGDTVAVA--REALAAGTAVDLAALGEAGALTVRTDVPAGHKVALRDVAAG 68

Query: 64  GEIIRYGEVIGYAVRAIPRGSWIDESMVVLPE----------APPLHTLPLATKVPEPLP 113
             + +YG++IG A   I  G  +    +               P  + + +  +    +P
Sbjct: 69  EAVRKYGQLIGLASAPIAAGEHVHVHNLAFTASQAGAGSADAGPGGYAVGVDARPTPLVP 128

Query: 114 PLEGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIE-RDLLPKYPNVDGVVG 172
           P E  TF+G   ADG V T+N +GI TSV+C A     +         L  YPNVDGVV 
Sbjct: 129 PAERRTFDGIVRADGRVATRNYIGILTSVNCSATAARRIADTFRWPGALDAYPNVDGVVA 188

Query: 173 LNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQA 232
           L H  GCG+      A +  RTI   + +PNF   ++VIGLGCE  Q   L +G D    
Sbjct: 189 LTHGTGCGMDALGEGAQLLRRTISGYARHPNFAA-LLVIGLGCEVNQVAALTSGFDLPP- 246

Query: 233 IPVESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSD 292
                  +V++  ++  G    V   ++     L  ++  +R   PASELV+G+ CGGSD
Sbjct: 247 ----EVPVVAMTIQEIGGTTRTVAAGVERVRELLPVVDAVRRVPVPASELVLGLNCGGSD 302

Query: 293 AFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWY 352
           A+SGVTANPA+G ASDLLV  G T + +E  EV  A HLLT RA + EV  +L+  + W+
Sbjct: 303 AWSGVTANPALGVASDLLVAQGGTSVLAETPEVYGAEHLLTRRARDPEVAAKLVRRIRWW 362

Query: 353 DNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIY 412
           + Y          NPSPGNK GGL  ++EK+LG++AK G +A+  V    +  T +G  +
Sbjct: 363 EEYTAAHGGSMDNNPSPGNKAGGLTTILEKSLGAVAKGGSAALEAVYEYAEPITAKGFTF 422

Query: 413 AATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINA 472
             TP  D V  T  VA G  V  FTTGRG+ +G    P IK+AT +E+  R  + MD++ 
Sbjct: 423 MDTPGYDPVSVTGLVAGGANVVCFTTGRGSVFGCKPAPSIKLATNSEVYARMDEDMDVDC 482

Query: 473 GTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHN-QLAVFNPAPV 522
           G + TGE+T+EE G +LF  IL+VASG++   S++ G+ + +   +    V
Sbjct: 483 GRVLTGEQTVEEAGRELFELILEVASGRRS-KSEELGVGDEEFQPWQLGAV 532


>UniRef50_C4X086 Altronate hydrolase n=14 Tax=Bacteria RepID=C4X086_KLEPN
          Length = 495

 Score =  595 bits (1534), Expect = e-168,   Method: Composition-based stats.
 Identities = 150/508 (29%), Positives = 237/508 (46%), Gaps = 18/508 (3%)

Query: 14  FYIKVHDTDNVAIIVNDNGLKAGTRFP-DGLELIEHIPQGHKVALLDIPANGEIIRYGEV 72
            YIK+H  DNVA+ + D    +      D + L + I +GHK AL  I     +++YG  
Sbjct: 2   QYIKIHSQDNVAVALTDIAAGSVVTIDNDSVTLGQDIVRGHKFALRAIAKGENVVKYGLP 61

Query: 73  IGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVGT 132
           IG+A+  I  G  +            L        +    P       + YR A+G VG 
Sbjct: 62  IGHALADIAPGEHVHAHNTR-TNLSDLDAYRYQPDLVAQPPQPADREVQIYRRANGDVGV 120

Query: 133 KNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPI 192
           +N L I  +V CV  +   +     ++      ++DGV   +H YGC    +       +
Sbjct: 121 RNELWILPTVGCVNAMARQMQNRFLKET-YGAEDIDGVHLFSHTYGCSQLGDDHINTRTM 179

Query: 193 RTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQ 252
             + N+  +PN  G V+V+GLGCE  Q E       +     V         DE      
Sbjct: 180 --LQNMVRHPN-AGAVLVVGLGCENNQVEAFRETLGEFDPQRVHFMVCQHQDDE------ 230

Query: 253 SMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVR 312
             VE  ++   +  + + Q +R+    SEL  G++CGGSD  SG+TANP +G  SD ++ 
Sbjct: 231 --VEAGVEHLHQLYEVMRQDKRQPGKLSELKFGLECGGSDGLSGITANPMLGRFSDYVIA 288

Query: 313 CGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNK 372
            G T + +EV E+  A  LL     +E    +L+  +  +  Y          NPSPGNK
Sbjct: 289 NGGTTVLTEVPEMFGAEQLLMSHCRDEATFDKLVTMVNDFKQYFIAHDQPIYENPSPGNK 348

Query: 373 KGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGIT 432
            GG+  + +K+LG   K+G S +V+VL  G+R    GL   + P +D V  +    +G  
Sbjct: 349 AGGITTLEDKSLGCTQKAGSSQVVDVLRYGERLKVHGLNLLSAPGNDAVATSALAGAGCH 408

Query: 433 VQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHF 492
           + +F+TGRGTPYG   VP +K+AT +ELA +    +D +AG +  G+ T+ ++  +    
Sbjct: 409 MVLFSTGRGTPYGG-FVPTVKIATNSELAAKKKHWIDFDAGQLLHGK-TMPQLLEEFVDA 466

Query: 493 ILDVASGKKKTFSDQWGLHNQLAVFNPA 520
           I+  A+GK     ++     +LA+F   
Sbjct: 467 IVAFANGKPTC--NEQNDFRELAIFKSG 492


>UniRef50_A6VSK2 Altronate dehydratase n=7 Tax=Proteobacteria RepID=A6VSK2_MARMS
          Length = 509

 Score =  590 bits (1522), Expect = e-167,   Method: Composition-based stats.
 Identities = 163/516 (31%), Positives = 266/516 (51%), Gaps = 9/516 (1%)

Query: 9   ETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDIPANGEIIR 68
            + ++  IK+H  DNV I+     +         L +   +  GHK+A   I A   II+
Sbjct: 2   SSSSSPLIKLHSNDNVCIVRESVSIGQQVP-EFNLRIRAQVSGGHKIAARLIEAGEPIIK 60

Query: 69  YGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADG 128
           Y   IG A+R I  G  +    + L +     +        + +      TF G   ++G
Sbjct: 61  YDTRIGVALRRIEAGDHVHTHNLELVDYERDPSFCQDVVPVDYVDVSARATFNGIVRSNG 120

Query: 129 SVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAA 188
            V T+N +GI ++V+C + V+  +      + L  +PNVDG+V   H  GCG++  +   
Sbjct: 121 KVATRNYIGILSTVNCSSTVIRQIADHFTPERLSAFPNVDGIVAFPHTSGCGMSSPSYHF 180

Query: 189 VVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKH 248
            V  RT+   + +PN  G V+++GLGCE+ +   L+      +      + + +L  +  
Sbjct: 181 DVLRRTLSGYARHPNLAG-VLIVGLGCERNEMSSLIASQQLEEN-----SHLQTLVMQAV 234

Query: 249 VGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASD 308
            G ++ +   +   E  L + N+  RE      L +G+QCGGSD FS +TANPA+G A D
Sbjct: 235 GGTRATIAAGIAAIESMLPEANKVVREPVSVEHLKIGLQCGGSDGFSAITANPALGMAMD 294

Query: 309 LLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPS 368
           +LVR G T + SE  E+    ++LT RA+++EVG++LL+ + W+D Y        +    
Sbjct: 295 ILVRHGGTAILSETPEIHGVEYMLTRRAISQEVGQKLLDRLSWWDEYTRGHNGQFNGVVG 354

Query: 369 PGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVA 428
            GN+ GGLAN+ EK+LGS  K G + +  V    +   + G ++  TP  D V  T Q+A
Sbjct: 355 QGNQAGGLANIFEKSLGSAMKGGTTPLQAVYEYAEPIEQNGFVFMDTPGYDPVSATGQIA 414

Query: 429 SGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWK 488
            G  +  FTTGRG+ +G    P IK+A+ + + NR  + MDIN G I  G+ ++EE+G  
Sbjct: 415 GGANLICFTTGRGSMFGSKPAPTIKLASNSNMYNRLQEDMDINCGLILDGKMSLEEMGQH 474

Query: 489 LFHFILDVASGKKKTFSDQWGLHN-QLAVFNPAPVT 523
           +F  I+ VASG+  T S++ GL + +   ++   V+
Sbjct: 475 IFEHIIKVASGE-STSSERLGLGDNEFIPWHIGIVS 509


>UniRef50_P42604 Altronate hydrolase n=77 Tax=Bacteria RepID=UXAA_ECOLI
          Length = 495

 Score =  590 bits (1521), Expect = e-167,   Method: Composition-based stats.
 Identities = 151/508 (29%), Positives = 236/508 (46%), Gaps = 18/508 (3%)

Query: 14  FYIKVHDTDNVAIIVNDNGLKAGTRFP-DGLELIEHIPQGHKVALLDIPANGEIIRYGEV 72
            YIK+H  DNVA+ + D             + L + + +GHK AL DI     +I+YG  
Sbjct: 2   QYIKIHALDNVAVALADLAEGTEVSVDNQTVTLRQDVARGHKFALTDIAKGANVIKYGLP 61

Query: 73  IGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVGT 132
           IGYA+  I  G  +            L          +          + YR A+G VG 
Sbjct: 62  IGYALADIAAGVHVHAHNTR-TNLSDLDQYRYQPDFQDLPAQAADREVQIYRRANGDVGV 120

Query: 133 KNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPI 192
           +N L I  +V CV G+   +     ++        DGV   +H YGC    +       +
Sbjct: 121 RNELWILPTVGCVNGIARQIQNRFLKET-NNAEGTDGVFLFSHTYGCSQLGDDHINTRTM 179

Query: 193 RTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQ 252
             + N+  +PN  G V+VIGLGCE  Q         D+    V         DE      
Sbjct: 180 --LQNMVRHPN-AGAVLVIGLGCENNQVAAFRETLGDIDPERVHFMICQQQDDE------ 230

Query: 253 SMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVR 312
             +E  ++   +    +   +RE    SEL  G++CGGSD  SG+TANP +G  SD ++ 
Sbjct: 231 --IEAGIEHLHQLYNVMRNDKREPGKLSELKFGLECGGSDGLSGITANPMLGRFSDYVIA 288

Query: 313 CGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNK 372
            G T + +EV E+  A  LL     +E   ++L+  +  +  Y          NPSPGNK
Sbjct: 289 NGGTTVLTEVPEMFGAEQLLMDHCRDEATFEKLVTMVNDFKQYFIAHDQPIYENPSPGNK 348

Query: 373 KGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGIT 432
            GG+  + +K+LG   K+G S +V+VL  G+R    GL   + P +D V  +    +G  
Sbjct: 349 AGGITTLEDKSLGCTQKAGSSVVVDVLRYGERLKTPGLNLLSAPGNDAVATSALAGAGCH 408

Query: 433 VQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHF 492
           + +F+TGRGTPYG   VP +K+AT +ELA +    +D +AG +  G+  + ++  +    
Sbjct: 409 MVLFSTGRGTPYGG-FVPTVKIATNSELAAKKKHWIDFDAGQLIHGKA-MPQLLEEFIDT 466

Query: 493 ILDVASGKKKTFSDQWGLHNQLAVFNPA 520
           I++ A+GK+ T +++     +LA+F   
Sbjct: 467 IVEFANGKQ-TCNER-NDFRELAIFKSG 492


>UniRef50_Q21ZN4 Galactarate dehydratase n=8 Tax=Proteobacteria RepID=Q21ZN4_RHOFD
          Length = 509

 Score =  586 bits (1511), Expect = e-166,   Method: Composition-based stats.
 Identities = 181/519 (34%), Positives = 263/519 (50%), Gaps = 15/519 (2%)

Query: 10  TPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRY 69
                 I++H  D+V I   +  +       + + +   IP GHK+A  +I     + RY
Sbjct: 1   MNAPAAIRLHINDDVVIA-RNQLISGTLIAQESVTVQGLIPAGHKMATRNIAEGEAVRRY 59

Query: 70  GEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGS 129
           G++IG+A R I  G  +    + +             +  + +P  E   F+G    DG 
Sbjct: 60  GQIIGFASRPIMAGQHVHVHNLSI--GDFNRDYAYGKESVDTVPATEAAFFQGIVRGDGR 117

Query: 130 VGTKNLLGITTSVHCVAGVVDYVVKIIER----DLLPKYPNVDGVVGLNHLYGCGVAINA 185
           V T+N +GI TSV+C A V   +     R    + L  YPNVDGVV L H  GC +    
Sbjct: 118 VATRNYIGILTSVNCSATVARAIADHFRRDIHPEALAAYPNVDGVVALTHGVGCAIDPQG 177

Query: 186 PAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQD 245
               V  RT+   + + NF   V++IGLGCE  Q   LL      + + +      +   
Sbjct: 178 EGLAVLQRTLGGYACHANF-ASVLIIGLGCETNQISDLLATQGLKENVRLH-----TFTI 231

Query: 246 EKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGY 305
           +   G    ++  +   +  L   N  QR+T  AS LVVG+QCGGSD +SG++ANP +G 
Sbjct: 232 QDTGGTVKTIQHGIDRIQEMLPAANAVQRQTVSASHLVVGLQCGGSDGYSGISANPVLGA 291

Query: 306 ASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSA 365
           A DLLVR G T + SE  E+  A HLLT RAV   VG++L++ + W++++          
Sbjct: 292 AVDLLVRQGGTAILSETPEIYGAEHLLTRRAVTPAVGEKLVQRIRWWEDHCKRNGASMDN 351

Query: 366 NPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQ 425
           NPS GNK GGL  V+EK+LG IAK G + +VEV    Q    +GL++  TP  D +  T 
Sbjct: 352 NPSSGNKAGGLTTVLEKSLGGIAKGGSTNLVEVYEYAQPVRAQGLVFMDTPGYDPISATG 411

Query: 426 QVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEV 485
           QVA G  +  FTTGRG+ YG    P +K+AT T L  R  D MDIN G +  G  TI E+
Sbjct: 412 QVAGGANLICFTTGRGSAYGCAPTPSLKLATNTALWQRQADDMDINCGDVLDGSATIAEL 471

Query: 486 GWKLFHFILDVASGKKKTFSDQWGL-HNQLAVFNPAPVT 523
           G + F  +L+ ASG++   S+  G   N+   +  + +T
Sbjct: 472 GQRFFQMMLETASGRQS-RSELHGYGQNEFVPWQLSVIT 509


>UniRef50_Q028V7 Altronate dehydratase n=1 Tax=Candidatus Solibacter usitatus
           Ellin6076 RepID=Q028V7_SOLUE
          Length = 511

 Score =  583 bits (1502), Expect = e-165,   Method: Composition-based stats.
 Identities = 181/509 (35%), Positives = 263/509 (51%), Gaps = 14/509 (2%)

Query: 15  YIKVHDTDNVAIIVNDNGLKAGTRFPDG-LELIEHIPQGHKVALLDIPANGEIIRYGEVI 73
            I +H TDNVA+           R     + + + IP GHK+AL DI     + RYG+VI
Sbjct: 15  VIHLHPTDNVAVARVPLPAGTELRVDGLPVTVRDAIPAGHKIALWDIAPGETVERYGQVI 74

Query: 74  GYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVGTK 133
           G A   I  G  I    +   E    +  P  T+   P P  +  TF GY   DG VGT+
Sbjct: 75  GRAKLPIDAGRHIHTHNLAYEELALDYEFP-TTETAVPTPRPDAPTFLGYPREDGRVGTR 133

Query: 134 NLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIR 193
           N + +  + +C A   + + +  E   LP  PNVDGVV   H  GCG A   P      R
Sbjct: 134 NYIAVVAASNCAAHAAELIARSYEGVTLP--PNVDGVVAFPHGEGCGHAF-GPDVDQLRR 190

Query: 194 TIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQS 253
           T+  + ++PN     +++GLGCE  Q +  L               +V +  +   G   
Sbjct: 191 TLGGVLVHPNVSA-ALILGLGCEVNQIDHYLGAGSPRTNR------LVGMTLQTSGGTPG 243

Query: 254 MVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRC 313
           ++    +   R  ++     R   PAS++++G+ CGGSD+FSG+TANPA+G+ SDLL   
Sbjct: 244 ILAAARREIGRFFEQAAAENRVPVPASKIILGLNCGGSDSFSGITANPALGFCSDLLAEL 303

Query: 314 GATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKK 373
           GA  + +E  E+  A HLL  RA N E+  +LL  +  Y  YL+        NPSPGNK+
Sbjct: 304 GAASVLAETPEIFGAEHLLVRRARNREIADKLLGCISRYKKYLSRFDGSFDDNPSPGNKE 363

Query: 374 GGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITV 433
           GGL+N++EK+LG++AK G S +++V    ++ T  G  +  TP  D V  T   A G  +
Sbjct: 364 GGLSNILEKSLGAVAKGGTSPLIDVYEYAEKITAPGFSFMNTPGYDPVSLTGLAAGGCNL 423

Query: 434 QVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFI 493
             FTTGRG+  G   +PVIK++T T       D MDINAG IA GE TI++ G ++FH +
Sbjct: 424 IAFTTGRGSAIGFPTIPVIKISTNTHTYRAMPDNMDINAGAIADGESTIQQTGREIFHAL 483

Query: 494 LDVASGKKKTFSDQWGLHNQLAVFNPAPV 522
           L +ASG + T +++ G H +   +   PV
Sbjct: 484 LAIASG-RPTCAERLG-HKEFVPWRIGPV 510


>UniRef50_O34673 Altronate hydrolase n=80 Tax=Bacteria RepID=UXAA_BACSU
          Length = 497

 Score =  582 bits (1501), Expect = e-165,   Method: Composition-based stats.
 Identities = 162/507 (31%), Positives = 255/507 (50%), Gaps = 17/507 (3%)

Query: 15  YIKVHDTDNVAIIVNDNGLKAGT-RFPDGLELIEHIPQGHKVALLDIPANGEIIRYGEVI 73
           +IK+H  DNV + + D         +   +E+ + I +GHK+AL  I  N  I++YG  I
Sbjct: 4   FIKIHKQDNVLLALRDIQKGERLHAYGVSIEVKDDIKRGHKIALQSIKENDSIVKYGFPI 63

Query: 74  GYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVGTK 133
           G+A + I  G  I            +       +  E     E  TF+G+R  +G  G +
Sbjct: 64  GHASQDISIGEHIHVHNTK-TNLSDIQLYSYTPRFDENPYSNENRTFKGFRRENGDAGVR 122

Query: 134 NLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIR 193
           N L I  +V CV G+ + +++   R+     P  D V+ L H YGC    +       I 
Sbjct: 123 NELWIVPTVGCVNGIAEKMLQRFVRETGDIAP-FDNVLVLKHQYGCSQLGDDHENTKQI- 180

Query: 194 TIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQS 253
            + N   +PN GG V+V+GLGCE  +  R+     DV    V+     S+ DE       
Sbjct: 181 -LLNAIRHPNAGG-VLVLGLGCENNELARMKEALQDVNLKRVKFLESQSVTDE------- 231

Query: 254 MVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRC 313
            +E  + + +   +     +RE  P SEL +G++CGGSD FSG+TANP +G  SD L+  
Sbjct: 232 -MEAGVALLKEIHEAAKGDKREDIPLSELKIGLKCGGSDGFSGITANPLLGRFSDYLIAQ 290

Query: 314 GATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKK 373
           G + + +EV E+  A  +L  RA NEEV  ++++ +  +  Y          NPSPGNK 
Sbjct: 291 GGSTVLTEVPEMFGAETILMQRAANEEVFHKIVDLINDFKQYFIKHDQPVYENPSPGNKA 350

Query: 374 GGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITV 433
           GG++ + +K+LG   K+G S + +VL  G+    +GL   + P +D +  +   A+G  +
Sbjct: 351 GGISTLEDKSLGCTQKAGISPVTDVLKYGEVLKTKGLTLLSAPGNDLIASSALAAAGCQI 410

Query: 434 QVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFI 493
            +FTTGRGTP+G   VP +K+AT TEL       +D NAG +A  +   E V  +  H++
Sbjct: 411 VLFTTGRGTPFGT-FVPTVKVATNTELYEAKPHWIDFNAGLLAEDDVHEEYVLREFIHYM 469

Query: 494 LDVASGKKKTFSDQWGLHNQLAVFNPA 520
           ++VASG+    + +     +LA+F   
Sbjct: 470 IEVASGQLV--NHEKNDFKELAIFKSG 494


>UniRef50_A9KNI4 Altronate dehydratase n=3 Tax=Clostridiales RepID=A9KNI4_CLOPH
          Length = 493

 Score =  582 bits (1500), Expect = e-164,   Method: Composition-based stats.
 Identities = 167/507 (32%), Positives = 263/507 (51%), Gaps = 21/507 (4%)

Query: 15  YIKVHDTDNVAIIVNDNGLKAGTRFPD-GLELIEHIPQGHKVALLDIPANGEIIRYGEVI 73
           ++K++  DNVA+ +ND             + L+E IP+GHK  L ++     +++YG  I
Sbjct: 4   FVKINSKDNVAVALNDLTKGMTIEVDGVAVTLVEDIPRGHKFTLANLNEGENVLKYGFPI 63

Query: 74  GYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVGTK 133
           G+  +A   GSW+    +       L T      V   L P E  TF GYR  +G VG +
Sbjct: 64  GHLTKAAEMGSWVHTQNIK-TNLGELLTYSYEPNV-NQLKPHEKATFMGYRRDNGKVGIR 121

Query: 134 NLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIR 193
           N + I  +V CV  + + + K  +  L     +V+ ++   H YGC    +       I 
Sbjct: 122 NEVWIIPTVGCVNKIAEAMEKQFKEKLTG---SVEDIIAFPHPYGCSQMGDDQENTRII- 177

Query: 194 TIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQS 253
            + ++  +PN    V+V+GLGCE      L     +     ++      ++DE       
Sbjct: 178 -LSDLINHPN-AAAVLVLGLGCENTNIAELKKYIGEYDEDRIKFLQCQDVEDE------- 228

Query: 254 MVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRC 313
            +E   ++ E+ +    + +RE   A ELV+GM+CGGSD  SG+TANP VG  SDLL+  
Sbjct: 229 -MEVAEELIEQLISYAAKFEREPISADELVIGMKCGGSDGMSGITANPTVGVFSDLLISQ 287

Query: 314 GATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKK 373
           G T + +EV E+  A  LL  R  NEE+  + ++ +  + NY          NPSPGNKK
Sbjct: 288 GGTTVLTEVPEMFGAETLLMARCENEELFDKTVDMINDFKNYFKSHNQTIYENPSPGNKK 347

Query: 374 GGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITV 433
           GG++ + +K+LG   KSG + + +VL  G+    +GL   + P +D V  T   ASG  +
Sbjct: 348 GGISTLEDKSLGCTQKSGSAPVKDVLKYGEIVKTKGLNLLSAPGNDLVASTALAASGAHM 407

Query: 434 QVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFI 493
            +FTTGRGTP+    VP +K++T T LA +  + +D N GT+  G+ T++ +G +LF ++
Sbjct: 408 VLFTTGRGTPFASP-VPTMKISTNTPLAMKKNNWIDFNCGTLVEGK-TLDILGEELFQYV 465

Query: 494 LDVASGKKKTFSDQWGLHNQLAVFNPA 520
           L VASGKK   S++ G H+ +A+F   
Sbjct: 466 LAVASGKKV-KSEEAGFHD-MAIFKSG 490


>UniRef50_D0D8F8 D-galactarate dehydratase n=2 Tax=Rhodobacteraceae
           RepID=D0D8F8_9RHOB
          Length = 498

 Score =  578 bits (1491), Expect = e-163,   Method: Composition-based stats.
 Identities = 177/514 (34%), Positives = 271/514 (52%), Gaps = 18/514 (3%)

Query: 10  TPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRY 69
                 + +  TD VA++++D          DG+  +E IP+GHKVA   + A   +++Y
Sbjct: 1   MSAPTIMVLDPTDTVAVVLSDMDAG---ETRDGITALEAIPRGHKVARKAMKAGDPVLKY 57

Query: 70  GEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGS 129
           G+V+  A   IP G+ +      LPE     +   A     P       TF+G+   DG 
Sbjct: 58  GQVMAVASVDIPEGAHVHVQNCALPEGSHGISAAQARLPEAPTRN----TFQGFARPDGR 113

Query: 130 VGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAV 189
           VGT+N +G+  SV+C   V D +     R LLPKYPNVDG   + H  GCG+A       
Sbjct: 114 VGTRNYIGVIASVNCSTTVCDAIAAEANRTLLPKYPNVDGFAPIVHDQGCGMANKGEGFD 173

Query: 190 VPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHV 249
             + T+     +PNFGG V++IGLGCE  Q           +          +   ++  
Sbjct: 174 ALVLTLKGYRDHPNFGG-VLIIGLGCEVNQLTLYKPTEWTRER-------FKTFNIQEVG 225

Query: 250 GFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDL 309
           G +S V+  L + E      N+  R   P S+L +GMQCGGSD FSG+TANPA+G ASD+
Sbjct: 226 GSRSAVKRALDLLEPIAAMANEDTRSEQPVSKLTLGMQCGGSDGFSGITANPALGVASDM 285

Query: 310 LVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSP 369
           LV  G T + SE  E+  A HLL  RA +E  G+++ + + W+ +Y +        NPSP
Sbjct: 286 LVTAGGTSILSETPEIYGAEHLLIARA-DEATGQKIEDMIVWWRDYASKNGASLDNNPSP 344

Query: 370 GNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVAS 429
           GNKKGGL  ++EK+LG++AK G + +    +  ++    G +Y  +P  D V  T QVAS
Sbjct: 345 GNKKGGLTTILEKSLGAVAKGGLAPLSGAFAYSEKIDTHGFVYMDSPGYDPVAATGQVAS 404

Query: 430 GITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKL 489
           G  +  FTTGRG+ +G    P IK+++ ++LA    + +DI+ G +     ++ E+G ++
Sbjct: 405 GANLIAFTTGRGSCFGAKPAPSIKLSSNSQLARSMAEDIDIDCGGVVEQGVSLTEMGERI 464

Query: 490 FHFILDVASGKKKTFSDQWGLHN-QLAVFNPAPV 522
           +  +LDVASG +KT S+++G  + +   +    V
Sbjct: 465 YDLLLDVASG-RKTMSEEFGYGDNEFVPWKIGAV 497


>UniRef50_D1BWK3 Galactarate dehydratase n=1 Tax=Xylanimonas cellulosilytica DSM
           15894 RepID=D1BWK3_XYLCX
          Length = 533

 Score =  575 bits (1483), Expect = e-162,   Method: Composition-based stats.
 Identities = 189/535 (35%), Positives = 277/535 (51%), Gaps = 29/535 (5%)

Query: 15  YIKVHDTDNVAIIVNDNGLKAGTRFPD-GLELIEHIPQGHKVALLDIPANGEIIRYGEVI 73
            + +H  D+VA+   D             +     +P+GHKVA+ D+P    + +YG+VI
Sbjct: 2   LLLLHPDDDVAVATRDLAAGETLDAGARTITTTGPVPRGHKVAVADLPPGAPVHKYGQVI 61

Query: 74  GYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVGTK 133
           G A   +  G  +    +        H L   T     +P     TF+GYR ADG VGT+
Sbjct: 62  GVATAPLAAGEHVHAHNLGFEAGHRDHQLG-GTHTELAVPAGPRPTFQGYRRADGRVGTR 120

Query: 134 NLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIR 193
           N + I TSV+C A     +        L  YPNVDGV+ L H  GCG+  ++    + +R
Sbjct: 121 NYVAILTSVNCSATTARMIAAQFGPQALAGYPNVDGVIALTHQSGCGLVPSSEGGQILLR 180

Query: 194 TIHNISLNPNFGGEVMVIGLGCEKLQPERL--LTGTDDVQAIPVESAS------------ 239
           T+   + +PN  G V+V+GLGCE +  E+L   +GT     +P                 
Sbjct: 181 TLRGYAAHPNIAG-VLVLGLGCEMVLTEQLTTRSGTGAFLGMPGVGTPPPPADPVLADIP 239

Query: 240 ----IVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFS 295
               + SL  ++  G ++ V   +   ER L  ++ R+RE C  ++LV+ + CGGSD +S
Sbjct: 240 ADTVVESLTIQESGGVRAAVTAGVAAVERMLAVVDTRRREICDVADLVLALNCGGSDGYS 299

Query: 296 GVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNY 355
           G+TANPA+G+ASD LV  GAT   +E  EV  A HLLT RAV  +V +RLL+ ++W+ +Y
Sbjct: 300 GLTANPALGWASDRLVAYGATSALAETPEVFGAEHLLTRRAVTPQVAQRLLDRIDWWQDY 359

Query: 356 LNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRP-TKRGLIYAA 414
              G      NPSPGNK GGL  ++EK+LG++AK G++ +  V    +R   + G ++  
Sbjct: 360 TRAGGGSMDNNPSPGNKAGGLTTILEKSLGAVAKGGQADLAAVYEYAERMAPRGGFVFMD 419

Query: 415 TPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGT 474
           TP  D V  T  VA G  V VFTTGRG+ +G    P IK+AT T +     D MD++AG 
Sbjct: 420 TPGYDPVSVTGLVAGGSNVVVFTTGRGSVFGCRPTPSIKVATNTPMYRAMSDDMDVDAGR 479

Query: 475 IATGEETIEEVGWKLFHFILDVASGKKKTFSDQWG------LHNQLAVFNPAPVT 523
           I  GE T+E+VG ++   IL VASG+  T S+            +   ++   VT
Sbjct: 480 IVEGEATVEQVGQEILDLILRVASGEP-TVSEDLQIAGVTIGAEEFVPWHVGAVT 533


>UniRef50_D0ZBA7 Altronate hydrolase n=15 Tax=Bacteria RepID=D0ZBA7_EDWTE
          Length = 496

 Score =  575 bits (1482), Expect = e-162,   Method: Composition-based stats.
 Identities = 151/507 (29%), Positives = 236/507 (46%), Gaps = 18/507 (3%)

Query: 15  YIKVHDTDNVAIIVNDNGLKAGTRFPDG-LELIEHIPQGHKVALLDIPANGEIIRYGEVI 73
            IK+H  DNVA+ + D          DG L L + +P+GHKVAL  +     +I+YG  I
Sbjct: 4   IIKIHPQDNVAVALRDLAAGETIALDDGALTLRDAVPRGHKVALCHLAPQAMVIKYGLPI 63

Query: 74  GYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVGTK 133
           G+A+  I  G  +    +       L +         P           YR A G V  +
Sbjct: 64  GHALTPIAAGDHVHAQNLR-TNLSDLDSYQYQPDFAAPTAQPADRAISLYRRASGEVAIR 122

Query: 134 NLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIR 193
           N L I  +V CV G+   +++   R+       +DGV    H +GC    +       + 
Sbjct: 123 NELWILPTVGCVNGMARQMLQRFLRES-DGASAIDGVHLFTHPFGCSQLGDDHQNTRTL- 180

Query: 194 TIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQS 253
            + N+  +PN GG V+V+GLGCE  Q         D     V         DE       
Sbjct: 181 -LQNMVHHPNAGG-VLVVGLGCENNQIAAFRETLGDYDPARVRFLVCQQQDDE------- 231

Query: 254 MVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRC 313
            VE   +        +   +RE    SEL  G++CGGSD FSG++ANP +G  SD ++  
Sbjct: 232 -VEAGTEALHELYGAMRGDRREPGRLSELKFGLECGGSDGFSGISANPLLGRFSDYVIAH 290

Query: 314 GATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKK 373
           G T + +EV E+  A  +L  R  + E  ++ +  +  +  Y    +     NPSPGNK 
Sbjct: 291 GGTSVLTEVPEMFGAERILMSRCRDGETFEKTVAMVNDFKRYFIDHQQPIYENPSPGNKA 350

Query: 374 GGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITV 433
           GG+  + EK+LG   K+G+S +++VL  G+R    GL   + P +D V  +   A+G  +
Sbjct: 351 GGITTLEEKSLGCTQKAGQSQVMDVLRYGERLHTPGLNLLSAPGNDAVATSALAAAGCHM 410

Query: 434 QVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFI 493
            +F+TGRGTPYG   VP +K+AT T LA +    +D +AG +  G+  +  +  +    I
Sbjct: 411 VLFSTGRGTPYGG-FVPTVKLATNTPLAAKKPHWIDFDAGQLLQGK-PMALLLSEFIDLI 468

Query: 494 LDVASGKKKTFSDQWGLHNQLAVFNPA 520
           + +A G++    ++     +LA+F   
Sbjct: 469 VAIADGRQTC--NEKNDFRELAIFKSG 493


>UniRef50_A7Z3M9 UxaA n=20 Tax=Bacteria RepID=A7Z3M9_BACA2
          Length = 497

 Score =  569 bits (1468), Expect = e-161,   Method: Composition-based stats.
 Identities = 154/509 (30%), Positives = 252/509 (49%), Gaps = 17/509 (3%)

Query: 13  AFYIKVHDTDNVAIIVNDNGLKAGTRFPD-GLELIEHIPQGHKVALLDIPANGEIIRYGE 71
              IK+H  DNV + +               +E+ + + +GHK+AL  I  NG II+YG 
Sbjct: 2   KEVIKIHKNDNVLLAMRHFDKGERLHTDGLTIEVKDPVKRGHKIALQTIEENGSIIKYGF 61

Query: 72  VIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVG 131
            IG A R I  G  I    +       +     + +  +     E  TF+GYR  +G+ G
Sbjct: 62  SIGRATRRISAGEHIHTHNLQ-TNLSDVQEYTYSPRFEDNPFTNENRTFKGYRRENGTSG 120

Query: 132 TKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVP 191
            +N L I  +V CV GV + +++   ++     P  D V+ L H YGC    +       
Sbjct: 121 VRNELWIVPTVGCVNGVAEKILQRFVKEAKDIAP-FDNVLVLKHQYGCSQLGDDHENTKQ 179

Query: 192 IRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGF 251
           +  + N   +PN GG V+V+GLGCE  +   +     +V    V+     ++ DE     
Sbjct: 180 M--LMNAIRHPNAGG-VLVLGLGCENNELAAIKETLSEVNGDRVKFLESQAVTDE----- 231

Query: 252 QSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLV 311
              +E    + +         +RE  P SEL +G++CGGSD FSG+TANP +G  SD L+
Sbjct: 232 ---IEAGTALLKEIHLAAKGDKREEIPLSELSIGLKCGGSDGFSGITANPLLGRFSDYLI 288

Query: 312 RCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGN 371
             G + + +EV E+  A  +L  RA +EEV  + +  +  +  Y    +     NPSPGN
Sbjct: 289 AQGGSTVLTEVPEMFGAETILMQRAASEEVFHKTVRLINDFKQYFMKHEQPIYENPSPGN 348

Query: 372 KKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGI 431
           K+GG++ + +K+LG   K+G + + +VL+ G+    +GL   + P +D +  +   A+G 
Sbjct: 349 KEGGISTLEDKSLGCTQKAGLAPVSDVLTYGETLKTKGLTLLSAPGNDLIASSALAAAGC 408

Query: 432 TVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFH 491
            + +FTTGRGTP+G   VP +K++T T+L       +D NAG +A  + T + +      
Sbjct: 409 HIVLFTTGRGTPFGT-FVPTVKVSTNTDLFQSKPHWIDYNAGRLAEDQTTEDHIVRDFIQ 467

Query: 492 FILDVASGKKKTFSDQWGLHNQLAVFNPA 520
           +I+ VASG+    +++     +LA+F   
Sbjct: 468 YIIKVASGEFV--NNEKNDFRELAIFKSG 494


>UniRef50_A0RPU2 Altronate hydrolase n=10 Tax=Bacteria RepID=A0RPU2_CAMFF
          Length = 505

 Score =  568 bits (1465), Expect = e-160,   Method: Composition-based stats.
 Identities = 164/513 (31%), Positives = 267/513 (52%), Gaps = 20/513 (3%)

Query: 15  YIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRYGEVIG 74
            I V + DN A  +    L        G+ +IE I +GHK A  DI     II+Y  +IG
Sbjct: 3   AIHVDEKDNAATALK---LIQKNSVELGVTIIEDISKGHKFATKDIKKGEAIIKYSSIIG 59

Query: 75  YAVRAIPRGSWIDESMVVLPEAPPLHT------LPLATKVPEPLPPLEGYTFEGYRNADG 128
            A + I +G+WI    +         +              +     + Y  +GYR +DG
Sbjct: 60  IANQDIKKGAWIHVHNIEGTRGRGDISGNLHIASQKLKNKKQAASNDKKYELQGYRRSDG 119

Query: 129 SVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAA 188
           S G +N + I  SVHC   VV+ +   I   L         +V + H +GC        A
Sbjct: 120 SFGLRNHILILPSVHCANKVVEKIAAAINYGLGLGNDECK-IVYVTHQHGCSQL--EFDA 176

Query: 189 VVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKH 248
              + T+     NPN  G V+VIGLGCE +  + +     D          +     ++ 
Sbjct: 177 RQTMDTLVGNGANPNVYG-VLVIGLGCEVISAQNVAKEIKDRAPY----KEVEYFTIQQS 231

Query: 249 VGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASD 308
            G +  +E  ++IA+  LQ   + ++     S+L++G +CGGSD+FSG++ANPA+G ASD
Sbjct: 232 GGTRKSIEKGIKIAKNMLQNALKFKKSRGDLSDLILGTECGGSDSFSGLSANPALGVASD 291

Query: 309 LLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTD-RSANP 367
           ++++ G +V+ +E TE+  A H+L  R++NE++ ++++  +  ++  +   K D R ANP
Sbjct: 292 IVIQKGGSVILAETTELIGAEHILAARSINEDIKEQVISTITSFEQRVLDSKADIRGANP 351

Query: 368 SPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQV 427
           SPGN +GGL+++ EK+LG I K+G   ++ V    Q  T++GL    TP +D    +  V
Sbjct: 352 SPGNIEGGLSSIEEKSLGCIYKAGNQPVISVKRYAQPITQKGLTLMDTPGNDIEQLSAMV 411

Query: 428 ASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGW 487
           A G  + VFTTGRGTP G    P IK+++ + + +   D +DINAG+I  G++ I+EVG 
Sbjct: 412 AGGCNICVFTTGRGTPTGSPITPTIKVSSNSAIYHNMNDAIDINAGSIIDGQKNIKEVGE 471

Query: 488 KLFHFILDVASGKKKTFSDQWGLHNQLAVFNPA 520
           ++  FI+ +++GK  T ++Q    N  +V+  A
Sbjct: 472 EILDFIVAISNGK-LTKAEQ-NDQNDFSVWRLA 502


>UniRef50_Q7UKI4 Altronate hydrolase n=2 Tax=Planctomycetales RepID=Q7UKI4_RHOBA
          Length = 634

 Score =  567 bits (1461), Expect = e-160,   Method: Composition-based stats.
 Identities = 172/525 (32%), Positives = 259/525 (49%), Gaps = 22/525 (4%)

Query: 15  YIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRYGEVIG 74
            +++HD DNV +      L AG    +       +P GHKVA   IPA   +I++G+ IG
Sbjct: 114 VVRLHDGDNVWMAAW--ALVAGETIGNLRIAGSAVPAGHKVAAQAIPAGELVIKFGQPIG 171

Query: 75  YAVRAIPRGSWIDESMVVLPEAPPLHTLP------LATKVPEPLPPLEGYTFEGYRNADG 128
            A   I  G  +    +V                   +   +        TFEG+   DG
Sbjct: 172 KASCDIGVGEHVHSHNLVDAHQVDSDWRSLVGTAFSKSAPAKKPAVPAEKTFEGFVRPDG 231

Query: 129 SVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAA 188
            VGT+N + I   V+C A V  +V      + L ++PNVDG+    H  GC +       
Sbjct: 232 QVGTRNYVQILARVNCSATVCHHVAARFPPERLAEFPNVDGIAIGTHTTGCALRYAGQKQ 291

Query: 189 VVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLT-----GTDDVQAIPV-----ESA 238
            +  R +   + + N  G  + IGLGCE+  PE L          D +++PV     ES 
Sbjct: 292 QMLGRVLKGYAGHANV-GSCLTIGLGCEQTTPEYLSEHHQLVAISDPRSLPVTSPESESV 350

Query: 239 SIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVT 298
           S   L  +   G ++ ++   +  E  L+  NQ  R T PA  L + ++CGGSD  SG T
Sbjct: 351 STTMLTMQAEGGTRATIDRAEKHLETMLEIANQNSRTTVPAHHLRLALECGGSDGHSGWT 410

Query: 299 ANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNM 358
           ANP VG  +D +V  G   + SE TE+  A HLL  R+ +E V +RL+++++W+  ++ M
Sbjct: 411 ANPLVGAIADRMVAFGGAAVLSETTELIGAEHLLVARSRDESVAQRLMDKVDWWKKHVAM 470

Query: 359 GKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPAS 418
              +   NPS GNK GGL  + EK+LG+++KSG   +  VL       K+GL    +P  
Sbjct: 471 YGGEIDNNPSIGNKAGGLTTITEKSLGAVSKSGTGILDGVLDYADTVPKQGLYVMDSPGF 530

Query: 419 DFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATG 478
           D    T +VA G  + +FTTGRG+ +G   VPVIK+A+ + L +   D MD NAG +  G
Sbjct: 531 DPSSVTGKVAGGCNLVLFTTGRGSCFGGKPVPVIKIASHSTLFHAMRDDMDWNAGQLLEG 590

Query: 479 EETIEEVGWKLFHFILDVASGKKKTFSDQWGLHN-QLAVFNPAPV 522
              +EE+  +LF  +L  ASG + T S++ GL + +   +   PV
Sbjct: 591 -VAMEELADQLFEELLRFASGTQ-TASERLGLGDHEFVPWTVGPV 633


>UniRef50_C9B1P2 Altronate dehydratase n=9 Tax=Bacteria RepID=C9B1P2_ENTCA
          Length = 503

 Score =  565 bits (1457), Expect = e-159,   Method: Composition-based stats.
 Identities = 165/511 (32%), Positives = 248/511 (48%), Gaps = 19/511 (3%)

Query: 11  PTAFYIKVHDTDNVAIIVNDNGLKAGTRFP-DGLELIEHIPQGHKVALLDIPANGEIIRY 69
             A  +K+H  DNVA+ +     K    F    + L E IPQGHK+AL D+  + ++I+Y
Sbjct: 8   TPAQLLKLHPKDNVAVALKPLAAKTTLAFEGQTITLFEDIPQGHKIALKDLAQSQDVIKY 67

Query: 70  GEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGS 129
           G  IG+ +  +  G W+    V             A  +     P    TF+GYR A+G 
Sbjct: 68  GYPIGHLLTDVKTGQWLHTHNVK-TNLSGTLAYTYAPDLHPVRYPKRAATFQGYRRANGK 126

Query: 130 VGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAV 189
           VG +N L I  +V C+ G+ + +V+  +++  P     D +  L H YGC          
Sbjct: 127 VGIRNDLLIVPTVGCINGIAEIIVENFKKNH-PDLGTFDHITILKHPYGCSQLGQDHQNT 185

Query: 190 VPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHV 249
             I  + +   +PN GG V+V GLGCE            D     V+        DE   
Sbjct: 186 RQI--LIDAVHHPNAGG-VLVFGLGCENNTVPEFKKNLGDYDPKRVKFMVAQESDDE--- 239

Query: 250 GFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDL 309
                +     + E  L+   + QRE  P SEL +G++CGGSD FSG+TANP +G  SD 
Sbjct: 240 -----IAVGESLLEELLEAAKEDQREAVPLSELKIGLKCGGSDGFSGITANPLLGAFSDF 294

Query: 310 LVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSP 369
           LV  G + + +EV E+  A  +L  RA +E   +++L  +  + +Y          NPSP
Sbjct: 295 LVSQGGSTVLTEVPEMFGAEQVLMARAQDEATFEKILHLINDFKDYFLAYGEPVYENPSP 354

Query: 370 GNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVAS 429
           GNK GG+  + +K+LG   KSG SA+V+VL  G++  K GL     P +D V  +   ++
Sbjct: 355 GNKAGGITTLEDKSLGCTQKSGTSAVVDVLKYGEKLRKPGLSLLEGPGNDLVAASALASA 414

Query: 430 GITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKL 489
              + +FTTGRGTP+G   VP +K+AT  E+ ++    MD NAG +    E +E V    
Sbjct: 415 DCQLVLFTTGRGTPFG-AYVPTMKVATNQEIYHKKPHWMDFNAGRLLE--EPMEVVLEDF 471

Query: 490 FHFILDVASGKKKTFSDQWGLHNQLAVFNPA 520
              I+D ASGK     ++     ++A+F   
Sbjct: 472 IQAIIDTASGKPT--RNEANNVREIAIFKNG 500


>UniRef50_D2QEC5 Altronate dehydratase n=2 Tax=Sphingobacteriales RepID=D2QEC5_9SPHI
          Length = 582

 Score =  560 bits (1443), Expect = e-158,   Method: Composition-based stats.
 Identities = 154/561 (27%), Positives = 236/561 (42%), Gaps = 60/561 (10%)

Query: 12  TAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGL-ELIEHIPQGHKVALLDIPANGEIIRYG 70
            A  +KVH  DNV + + +        F + L EL   +   HK    D      I  YG
Sbjct: 27  PARVLKVHPADNVIVALRNLAAGEKIEFENTLYELPYAVGAKHKFVTEDRQPGDPITMYG 86

Query: 71  EVIGYAVRAIPRGSWIDESMVVLPE--APPLHTLPLATKVPEPLPPLEGYTFEGYRNADG 128
            ++G A + I RG  I    +             P + + P  L   EG TF GY  ADG
Sbjct: 87  VLVGKATQPIRRGEPITTFNLKHDADTYGLDKKQPYSWQPPNTLA-WEGRTFMGYHRADG 145

Query: 129 SVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYP----------------------- 165
           SVGT+N   +   V C    V  +    ER+L    P                       
Sbjct: 146 SVGTRNYWLVVPLVFCENRNVLILKDAFERELGYAQPETYRVQVHELLSLYKAGEMDIAK 205

Query: 166 --------------------------NVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNIS 199
                                     NVDG+  L H  GCG        +  +  +    
Sbjct: 206 KMQPFVDESQNQTLNSARHQANRPFKNVDGIKFLTHEMGCGGTRQDSGYLCSL--LAGFI 263

Query: 200 LNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDIL 259
            NPN  G   V+ LGC+ LQ + +       +  P     ++  + +      +++ + +
Sbjct: 264 NNPNVAG-ATVLSLGCQHLQTDMISAEIK--RQNPKFDKPLLLFEQQ-AGTEYALMSEAV 319

Query: 260 QIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMF 319
           +     L  +N+ +R+  P S L VG++CGGSD FSG++ANPA+G  SD+LV  G   + 
Sbjct: 320 KQTFLGLVDINKLERQPAPLSALTVGLKCGGSDGFSGISANPALGQLSDILVTLGGKTVL 379

Query: 320 SEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGLANV 379
           +E  E+      L  R  + +  ++ +  M  Y        +    NPSPGN K GL   
Sbjct: 380 AEFPELNGVEQELINRTDDTDKAQKFITLMGDYSAQAEAVGSGFDMNPSPGNIKDGLITD 439

Query: 380 VEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTG 439
             K+ G+  K G + + +VL   +  T  GL    TP +D    T    SG  V +FTTG
Sbjct: 440 AIKSAGAAKKGGTAPVADVLDYAEPATTPGLNLLCTPGNDVEATTGMAGSGTNVILFTTG 499

Query: 440 RGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASG 499
            GTP G    PV+K++T T L NR  D++D ++G I  GE++IE+    +  +I+ +ASG
Sbjct: 500 LGTPTGNPVCPVVKVSTNTVLKNRMPDVIDFDSGPIIDGEQSIEQNANAMLEYIIKLASG 559

Query: 500 KKKTFSDQWGLHNQLAVFNPA 520
           +  T +++ G  +    +   
Sbjct: 560 EVITQAERLG-QDDFIPWKRG 579


>UniRef50_A0M231 Altronate hydrolase n=9 Tax=Bacteria RepID=A0M231_GRAFK
          Length = 553

 Score =  559 bits (1440), Expect = e-157,   Method: Composition-based stats.
 Identities = 156/552 (28%), Positives = 230/552 (41%), Gaps = 49/552 (8%)

Query: 12  TAFYIKVHDTDNVAIIVNDNGLKAGTRFPDG-LELIEHIPQGHKVALLDIPANGEIIRYG 70
              Y ++   DN+ + + D               L E I Q HK AL D     EII YG
Sbjct: 5   AQPYSQIDTRDNIIVAIQDLPKSTIVNIAGKDFPLEEAIKQKHKFALYDFQIGDEIIMYG 64

Query: 71  EVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSV 130
            ++G A++ I RG+ I    +    A               +      TF+GY  ADGSV
Sbjct: 65  VLVGEAIQPIKRGAAITTKNIKHASAEFNSEQSKYKWTAPDISKYTERTFKGYHRADGSV 124

Query: 131 GTKNLLGITTSVHCVAGVVDYVVKIIERDLLPK--------------------------- 163
           GT+N   +   V C    +D V   +   L  +                           
Sbjct: 125 GTRNYWLVIPLVFCENRNIDVVQDALMEALGYQTNKDYSVDTPKLIEKYKNGASPEELME 184

Query: 164 ---------------YPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEV 208
                          +PNVDG+  L H  GCG            R +     N N  G  
Sbjct: 185 TSIVHTTEELTKNRLFPNVDGIKFLKHDGGCGGIRQDSET--LCRLLAGYITNSNVAG-A 241

Query: 209 MVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQIAERHLQK 268
            ++ LGC+  Q + L     +          +  L+ ++    +  +E  ++     L +
Sbjct: 242 TILSLGCQNAQMDMLQNAIAEKDKN--FQKPVYYLEQQQIGNERKFIETAVKKTFIGLSQ 299

Query: 269 LNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDA 328
            N+  R+    ++LV+G++CGGSD FSG++ N A+GYASDLL   G + + SE  E+   
Sbjct: 300 TNKIDRKPAALNKLVLGLECGGSDGFSGISCNSALGYASDLLTALGGSPVLSEFPELNGV 359

Query: 329 IHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIA 388
              L  R   +E  ++    M  Y        +    NPSPGN K GL     K+ G+  
Sbjct: 360 EQELINRCNEKEDAEKFANIMNRYSQRAKDVGSGFENNPSPGNIKDGLITDAMKSAGAAK 419

Query: 389 KSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMA 448
           K G S +  VL   ++    GL    TP +D    T    SG  + VFTTG GTP G   
Sbjct: 420 KGGTSPVTSVLDYTEKVKTPGLNLLCTPGNDVESTTGLAGSGCNMIVFTTGLGTPTGNPV 479

Query: 449 VPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQW 508
            PV+KM++ T L  R  D++DINAGT+ TGE+TI+ +G K+   I+ VASG+K+  +   
Sbjct: 480 APVLKMSSNTALFERMNDIIDINAGTVITGEDTIQSMGEKILDEIILVASGEKEAKA-VL 538

Query: 509 GLHNQLAVFNPA 520
              N    +   
Sbjct: 539 QNQNDFIPWKRG 550


>UniRef50_C5SJY8 Altronate dehydratase n=3 Tax=Proteobacteria RepID=C5SJY8_9CAUL
          Length = 515

 Score =  555 bits (1431), Expect = e-156,   Method: Composition-based stats.
 Identities = 165/508 (32%), Positives = 255/508 (50%), Gaps = 19/508 (3%)

Query: 14  FYIKVHDTDNVAIIVNDNGLKAGTRFPD-GLELIEHIPQGHKVALLDIPANGEIIRYGEV 72
            Y++VH TD+VAI V          F D  L L   IP+GHK+AL DI     ++++G  
Sbjct: 23  RYVRVHATDDVAIAVEALSAGEVLDFGDVQLTLGTDIPKGHKIALRDIAEGAPVLKFGFR 82

Query: 73  IGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVGT 132
           IG+A+  I  G  +    +                   P    +  TF GYR ADG VG 
Sbjct: 83  IGHAIAPIKTGEHVHTHNLSTSLTGVEDYDYAPVAAEGPGSRPDARTFMGYRRADGRVGI 142

Query: 133 KNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPI 192
           +N + I  +V CVA   + + K+       +   VDGV  L H  GC    +        
Sbjct: 143 RNEIWILCTVGCVARTSERLAKVASERFKGR---VDGVYALTHPLGCSQLGDDLNHTR-- 197

Query: 193 RTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQ 252
           + +  ++ +PN GG V+++GLGCE  Q   L+   +      ++  +   ++DE      
Sbjct: 198 KLLAALAAHPNAGG-VLIVGLGCENNQLSALIGEIEGRTPDRLKYFAAQMVEDE------ 250

Query: 253 SMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVR 312
              E  L+  E  +Q + + QRE C  S+L +G++CGGSD FSG+TANP VG  +D++  
Sbjct: 251 --HESGLEALEALVQVVEKDQRELCHVSDLAIGVKCGGSDGFSGLTANPLVGRVADIVAL 308

Query: 313 CGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNK 372
            G   + +E+ EV  A  +L  RA +E V  ++++ +  +  Y          NPSPGNK
Sbjct: 309 AGGQSIMTEIPEVFGAERILMARAKDEGVFHQIVDVVNDFKQYFLDNNQPVFENPSPGNK 368

Query: 373 KGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGIT 432
            GG++ + EK+LG++ K G S + EVL  G+R T+ GL     P +D V  T   A+G  
Sbjct: 369 AGGISTLEEKSLGAVQKGGLSQLTEVLRYGERATQAGLSLLEAPGNDAVSSTALTAAGAV 428

Query: 433 VQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHF 492
           + +FTTGRGTP G    P +K+A+ T LA +    +D NAG    G+ T++E    L   
Sbjct: 429 IVLFTTGRGTPLGFP-APTLKIASNTALAEKKPHWIDFNAGQALEGK-TLDETADDLMDL 486

Query: 493 ILDVASGKKKTFSDQWGLHNQLAVFNPA 520
           IL VASG++   +++     ++A++   
Sbjct: 487 ILRVASGER--ANNEKNDEREIAIWKNG 512


>UniRef50_C4STJ6 Altronate dehydratase n=1 Tax=Yersinia frederiksenii ATCC 33641
           RepID=C4STJ6_YERFR
          Length = 529

 Score =  551 bits (1420), Expect = e-155,   Method: Composition-based stats.
 Identities = 137/532 (25%), Positives = 225/532 (42%), Gaps = 31/532 (5%)

Query: 13  AFYIKVHDTDNVAIIVNDNGLKAGT-RFPDGLELIEHIPQGHKVALLDIPANGEIIRYGE 71
           +  +K+ ++DN+ + + +           D   L+  +   HK ++ DI   G +  YG 
Sbjct: 2   SKILKIDESDNLIVALKNLQKGETVCWGDDHFTLMTDVKAKHKFSVEDIAIGGIVSMYGT 61

Query: 72  VIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVG 131
            +G A + I +G  +    +    AP              +      TF+GY  +DG VG
Sbjct: 62  PVGKATKPIAKGEAVTVDNIKHYAAPVQLNDEQYNWQAPDISSYIDRTFKGYLRSDGRVG 121

Query: 132 TKNLLGITTSVHCVA--------------GVVDYVVKIIERDLLPKY---------PNVD 168
           T N   +   V C                G  D+ +     +L             P+++
Sbjct: 122 TANYWLVFPLVFCENRNVTKLTDALNDALGYSDHSLTRFAMNLAGGDAPQVKEKLLPHIE 181

Query: 169 GVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTD 228
           GV  +    GCG A +          +   + +PN  G + V  LGCEK Q         
Sbjct: 182 GVRSITVSSGCGGAASDSMT--MCEVLAAYADHPNVIG-ITVFSLGCEKAQVIDFKDALK 238

Query: 229 DVQAIPVESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQC 288
                P  S   +  + ++    + M++  L+     + ++    R   P S L +G++C
Sbjct: 239 KCN--PQFSKPTLYFKQQEWENEEQMMQSALKETFACMNEVQPTPRVDVPLSHLKLGVKC 296

Query: 289 GGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEE 348
           G SD FSG++ NPA+G  SD +V  G     +E  E+  A   +  R  + E   + L  
Sbjct: 297 GASDGFSGISGNPAMGLVSDWVVTLGGASALAEFPELCGAEGDMVKRCRHPEDKSKFLSL 356

Query: 349 MEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKR 408
           M  Y+   N   T  + NPSPGN   GL     K+ G+  K G++ I  V    +     
Sbjct: 357 MAGYEKTANFFNTSIADNPSPGNIADGLITDAIKSTGAAKKGGRAPISAVCDYAEPMPDT 416

Query: 409 GLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLM 468
           GL    TP +D V  T  VA+G  V +F+TG GTP G   VPV+K++T TE+ANR  D++
Sbjct: 417 GLSLVCTPGNDVVAVTGLVAAGCNVVIFSTGLGTPTGNPIVPVLKISTNTEIANRLKDII 476

Query: 469 DINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPA 520
           D + G +  G   + +V   LF  +++ AS      SD+   ++   ++  +
Sbjct: 477 DFDCGPVIEG-TPLSDVSQALFERVIETASRDYVVKSDRLEQYD-FLLWKRS 526


>UniRef50_B0T3J7 Altronate dehydratase n=15 Tax=Bacteria RepID=B0T3J7_CAUSK
          Length = 514

 Score =  550 bits (1418), Expect = e-155,   Method: Composition-based stats.
 Identities = 153/504 (30%), Positives = 243/504 (48%), Gaps = 20/504 (3%)

Query: 18  VHDTDNVAIIVNDNGLKAGTRFP-DGLELIEHIPQGHKVALLDIPANGEIIRYGEVIGYA 76
           V   D+VA  + D             +     IP+GHK+A+       ++++YG  IG A
Sbjct: 27  VDPRDHVATALRDLLAGETLDLHGQTIVASTDIPKGHKIAVRAARLGEDLLKYGWPIGRA 86

Query: 77  VRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVGTKNLL 136
              I  G  +    V       +         PEP       TF GYR  +G VGT+N +
Sbjct: 87  TADIAVGDHVHVHNVE-TRLSGVEHFTYTAGHPEPRQAPPLATFLGYRRKNGRVGTRNEI 145

Query: 137 GITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIH 196
            +  +V CVA     + +        +   +DGV    H +GC    +        + I 
Sbjct: 146 WVLCTVGCVANTARRIAEKANARFAGR---IDGVFAFPHPFGCSQLGDDLTHTR--KLIA 200

Query: 197 NISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVE 256
            ++ +PN GG V+++GLGCE  Q + LL     +    + S +   ++DE        +E
Sbjct: 201 GLAAHPNAGG-VLILGLGCENNQLKALLESAPGLDPERLRSFTTQMVEDE--------LE 251

Query: 257 DILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGAT 316
           D L   E  ++   + +RE  P S+LV+G++CGGSD FSGVTANP VG  +D +   G T
Sbjct: 252 DGLDAIEALVEIAERDRREPMPLSDLVIGLKCGGSDGFSGVTANPLVGRIADKVSNAGGT 311

Query: 317 VMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGL 376
            + +E+ EV  A  +L  RA   +V  + +  ++ +  Y          NPSPGN  GG+
Sbjct: 312 PVLTEIPEVFGAEGVLLARAATRQVFDQAVGVIDDFKRYFIDNHQPIYENPSPGNIAGGI 371

Query: 377 ANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVF 436
             + EK+LG++ K G+S +VEVL  G++    GL     P +D V  T   A+G TV +F
Sbjct: 372 TTLEEKSLGAVQKGGRSMLVEVLRYGEQVGSHGLTLLEAPGNDAVSSTALTAAGATVILF 431

Query: 437 TTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDV 496
           TTGRGTP G    P +K+A+ + LA R    +D +AG + +G +T++     L   ++  
Sbjct: 432 TTGRGTPLGFP-APTLKIASNSALAARKPGWIDFDAGVVLSG-QTMDAAADSLMDLVVAT 489

Query: 497 ASGKKKTFSDQWGLHNQLAVFNPA 520
           ASG++ T ++      ++A++   
Sbjct: 490 ASGQQ-TKAE-LNGEREIAIWKTG 511


>UniRef50_C1NB77 Altronate dehydratase n=2 Tax=Enterobacteriaceae RepID=C1NB77_9ESCH
          Length = 533

 Score =  549 bits (1416), Expect = e-155,   Method: Composition-based stats.
 Identities = 142/534 (26%), Positives = 229/534 (42%), Gaps = 35/534 (6%)

Query: 14  FYIKVHDTDNVAIIVNDNGLKAGTRFPD-GLELIEHIPQGHKVALLDIPANGEIIRYGEV 72
             +++   DN+ + + D        + D  + L+  +   HK A  DIP +G +  YG  
Sbjct: 5   KILRIDSNDNLIVALKDLHAGESFSWDDDNITLVTDVKAKHKFATQDIPLDGIVSMYGTP 64

Query: 73  IGYAVRAIPRGSWIDESMVVLPEAPPLHTL--PLATKVPEPLPPLEGYTFEGYRNADGSV 130
           +G A R I +G  I    +    AP       P   + P+ +      TF+GY   DG V
Sbjct: 65  VGKATRPIVKGEAITVDNIRHYAAPVTLEDVEPYHWQAPD-VSEWSTRTFKGYVRDDGRV 123

Query: 131 GTKNLLGITTSVHCVAGVVDYVVKIIERDLLPK------------------------YPN 166
           GT +   +   V C    V  +   +   L                           +P+
Sbjct: 124 GTASYWLVFPLVFCENRNVSKLTNALNDALGYTNNSLKKFALNLTSGSDELIETARMFPH 183

Query: 167 VDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTG 226
           ++GV  +    GCG A +          +   + +PN  G + V  LGCEK Q +     
Sbjct: 184 IEGVRCITVTSGCGGATSDCET--MCDVLAAYADHPNVIG-MTVFSLGCEKAQQKMFKDA 240

Query: 227 TDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGM 286
               +  P      +    ++    + M++  LQ     ++ +   +R   P S L VGM
Sbjct: 241 LA--RRNPEFDKPALYFLQQEWDSEERMMQTALQQTFEAMKAVKPTERVEVPLSCLKVGM 298

Query: 287 QCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLL 346
           +CGGSD FSG++ NPA+G  SD L   G     +E  E+  A   +  R +N E  K+ L
Sbjct: 299 KCGGSDGFSGISGNPAMGLVSDWLTTLGGASGLAEFPELCGAEGDMVKRCINLEDKKKFL 358

Query: 347 EEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPT 406
             M+ Y+   N   T  + NPS GN   GL     K+ G+  K G++ IV V    +   
Sbjct: 359 NLMQGYEKTANFFDTTIADNPSFGNIADGLITDAIKSTGAAKKGGRAPIVSVCDYAEPMP 418

Query: 407 KRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFD 466
             GL    TP +D    T  VA+G  V +F+TG GTP G   VPV+K++T + +A R  D
Sbjct: 419 DSGLSLVCTPGNDVDAVTGLVAAGCNVVIFSTGLGTPTGNPIVPVLKISTNSTIARRLSD 478

Query: 467 LMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPA 520
           ++D + G +  G   +E+V  +LF  +++ AS      +D+    +   ++  +
Sbjct: 479 MIDFDCGPVIDG-TPLEDVSRELFEKVIETASKDYVVKADKLEQFD-FMLWKRS 530


>UniRef50_UPI0001C34772 Altronate dehydratase n=1 Tax=Providencia rettgeri DSM 1131
           RepID=UPI0001C34772
          Length = 531

 Score =  546 bits (1406), Expect = e-153,   Method: Composition-based stats.
 Identities = 143/536 (26%), Positives = 235/536 (43%), Gaps = 39/536 (7%)

Query: 14  FYIKVHDTDNVAIIVNDNGLKAGTRFPDG---LELIEHIPQGHKVALLDIPANGEIIRYG 70
             +K+ ++DN+ + + D  L+AG  +  G   + L+  +   HK A+  IP +G +  YG
Sbjct: 3   KILKIDESDNLIVALKD--LQAGDIYHWGSEEVTLVTDVKAKHKFAMEAIPVDGIVSMYG 60

Query: 71  EVIGYAVRAIPRGSWIDESMVVLPEAPP--LHTLPLATKVPEPLPPLEGYTFEGYRNADG 128
             +G A + I +G  I    +    AP       P     P+ +   +G TF+GY   DG
Sbjct: 61  TAVGKATKPIAKGEVITVDNIRHYAAPVSLEQDAPYEWNAPD-VSAYQGRTFKGYIREDG 119

Query: 129 SVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPK------------------------Y 164
            VGT N   I   V C    V  +   +   L                           +
Sbjct: 120 RVGTANYWLIFPLVFCENRNVTKLTDALNEALGYTNNSLKNFALDLTAGEQREGAKPKLF 179

Query: 165 PNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLL 224
           P+++GV  +    GCG A +          +   + +PN  G + V  LGCEK Q +   
Sbjct: 180 PHIEGVRCITVTSGCGGATSDSKT--MCDVLAAYADHPNVIG-ITVFSLGCEKAQRKMFK 236

Query: 225 TGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVV 284
                  +    +   +  + ++    + M++  L+     ++ +  + R   P   L +
Sbjct: 237 ESLAARNSN--FNKPALYFRQQEWNSEEEMMQTALKQTYECMKAVEPQSRVDVPLFHLKL 294

Query: 285 GMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKR 344
           G++CG SD FSG++ NPA+G  SD LV  G     +E  E+  A   +  R V+ E  ++
Sbjct: 295 GVKCGASDGFSGISGNPAMGLVSDWLVTLGGASGLAEFPELCGAEGDMVKRCVSFEDKRK 354

Query: 345 LLEEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQR 404
            L+ ME Y+   N   T  + NPSPGN   GL     K+ G+  K G S I  V    + 
Sbjct: 355 FLDLMERYEKTANFFNTTIADNPSPGNIADGLITDAIKSTGAAKKGGTSPISAVCDYAEP 414

Query: 405 PTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRW 464
               GL    TP +D    T  VA+G  V +F+TG GTP G   VPV+K++T + +A R 
Sbjct: 415 MPDSGLSLVCTPGNDVDAVTGLVAAGCNVVIFSTGLGTPTGNPIVPVLKISTNSAIAERL 474

Query: 465 FDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPA 520
            D++D + G I  G   +  +   LF  +++ ASG  +  +D+    +   ++  +
Sbjct: 475 SDIIDYDCGPIIDG-VPLPTISKGLFERVIETASGDYQVQADRLEQFD-FLLWKRS 528


>UniRef50_C6J327 Altronate dehydratase n=1 Tax=Paenibacillus sp. oral taxon 786 str.
           D14 RepID=C6J327_9BACL
          Length = 494

 Score =  541 bits (1393), Expect = e-152,   Method: Composition-based stats.
 Identities = 150/480 (31%), Positives = 239/480 (49%), Gaps = 20/480 (4%)

Query: 2   ANIEI---RQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRF-PDGLELIEHIPQGHKVAL 57
           ++I +   RQ       +K++  DNV + +         +   + +   + IPQGHK+AL
Sbjct: 29  SDITMVGRRQLMR--RLMKMNPRDNVGVALQPITAGEELQLNEESVRAAQDIPQGHKIAL 86

Query: 58  LDIPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEG 117
             IPA   + +YG  IG+ V AI  G W+    +                +   + P   
Sbjct: 87  TAIPAGSSVTKYGYSIGHVVTAIAPGEWVHTHNIR-TNLAGEEQYVYQPNLHPVIYPKRS 145

Query: 118 YTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLY 177
           +TF+GYR A+G  G +N L I  +V CV G+ + +++  + +     P  D +  L+H Y
Sbjct: 146 FTFQGYRRANGKTGIRNDLYIVPTVGCVNGIAEQMIRAFKAEHPDLGP-FDNITVLSHPY 204

Query: 178 GCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVES 237
           GC         ++    + +  L+PN GG V+V GLGCE                  V+ 
Sbjct: 205 GCSQL--GEDHLMTRSILADTVLHPNAGG-VLVFGLGCENNVVSEFRERLGHYDEQRVKF 261

Query: 238 ASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGV 297
                ++DE        +E  L + E  ++     +RE  P SE+ VG++CGGSD+FSG+
Sbjct: 262 LVAQEVEDE--------LEAGLALLEELVEAARNDRREPVPLSEMNVGLKCGGSDSFSGI 313

Query: 298 TANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLN 357
           TANP +G  SD L+  G + + +EV E+  A  +L  RA ++EV ++++  +  +  Y  
Sbjct: 314 TANPLLGAFSDFLISQGGSTILTEVPEMFGAEKMLMARAESQEVFEQIVVLINDFKQYFL 373

Query: 358 MGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPA 417
                   NPSPGNK GG++ + +K+LG   K+G + +V+VL  G++  K+GL    TP 
Sbjct: 374 FYGEPVYENPSPGNKAGGISTLEDKSLGCTQKAGTAPVVDVLKYGEKLRKKGLSLLQTPG 433

Query: 418 SDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIAT 477
           +D V  +   A+   + +FTTGRGTP+G   VP +K+AT  EL  R    MD NAG +  
Sbjct: 434 NDLVASSALAAADCQLVLFTTGRGTPFGS-FVPTVKVATNNELFARKQHWMDFNAGVLLD 492


>UniRef50_C7PV23 Altronate dehydratase n=13 Tax=Bacteria RepID=C7PV23_CHIPD
          Length = 554

 Score =  540 bits (1392), Expect = e-152,   Method: Composition-based stats.
 Identities = 161/553 (29%), Positives = 236/553 (42%), Gaps = 54/553 (9%)

Query: 14  FYIKVHDTDNVAIIVNDNGLKAGTRFPDGL-ELIEHIPQGHKVALLDIPANGEIIRYGEV 72
             +KVH  DNV + + D       +    +  L E +P  HK     +     I  YG +
Sbjct: 7   KVLKVHPQDNVVVALTDLKKGESVQENGRVYTLAEDVPAKHKFTETILHPGDAITMYGVL 66

Query: 73  IGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPP---LEGYTFEGYRNADGS 129
           +G A   +P G+ I    V    A     L    K    +P     +  TF GY  ADGS
Sbjct: 67  VGKAKELLPAGAKIAVGNVQH--ASSDFQLAATRKTAWHIPDISKWQDRTFMGYHRADGS 124

Query: 130 VGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYP------------------------ 165
           VGT N   +   V C    V+ + + +  +L    P                        
Sbjct: 125 VGTGNYWLVIPMVFCENRNVEVLRETLVEELGYGRPKKYAAFARQLAQQYQQGADASAIL 184

Query: 166 ------------------NVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGE 207
                             NVDG+  L H  GCG        +  +  +     + N  G 
Sbjct: 185 ETVYTEDPAQQGQQRLFENVDGIKFLTHEGGCGGIRQDAQTLCGL--LAGYITHANVAG- 241

Query: 208 VMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQIAERHLQ 267
             V+ LGC+  Q   L          P  S  +  L  ++    Q+++   ++     L 
Sbjct: 242 ATVLSLGCQNAQITMLEEEIRKRS--PDFSKPLFILDQQQTGTEQALITAAVRQTMAGLI 299

Query: 268 KLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRD 327
           + N+  R   P  +L +G++CGGSD FSG++ANPA+GY SDLLV  G +V+ SE  E+  
Sbjct: 300 EANKITRTPAPLYKLCIGLECGGSDGFSGISANPAIGYTSDLLVALGGSVILSEFPELCG 359

Query: 328 AIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSI 387
               ++ R VN     R +E M  Y        +    NPSPGN K GL     K+ G+ 
Sbjct: 360 VEQEMSDRCVNTTDALRFIELMRTYQRRAEEAGSGFDMNPSPGNIKDGLITDAIKSAGAA 419

Query: 388 AKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLM 447
            K G S +  VL   Q+ +  GL    TP +D    T +V +G T+ +FTTG GTP G  
Sbjct: 420 KKGGTSPVAAVLDYPQKVSLPGLNLLCTPGNDVESTTAEVGAGATIVLFTTGLGTPTGNP 479

Query: 448 AVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQ 507
             PVIK+++ T+L  R  D++DIN GTI  GEE+I E G ++ ++++DVASG  K  S  
Sbjct: 480 VTPVIKLSSNTKLYQRMPDIIDINTGTIIDGEESIPEAGERILNYVIDVASGITKARS-V 538

Query: 508 WGLHNQLAVFNPA 520
               +    +   
Sbjct: 539 INGQDDFIPWKRG 551


>UniRef50_B5FMP6 Hydrolase, UxaA family n=75 Tax=cellular organisms
           RepID=B5FMP6_SALDC
          Length = 408

 Score =  483 bits (1243), Expect = e-135,   Method: Composition-based stats.
 Identities = 133/406 (32%), Positives = 204/406 (50%), Gaps = 23/406 (5%)

Query: 117 GYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHL 176
             TF G+R  DG  G +N + I  +  C   V   + +            V G   +N+ 
Sbjct: 23  NETFLGFRRPDGRFGIRNYVLILPTSVCANKVARDIARQ-----------VKGATWVNND 71

Query: 177 YGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVE 236
           +GC        A +  +T+ N++ NPN G  V V+GLGCE  +P R+             
Sbjct: 72  FGCCQVAGD--ARLTEKTLINVANNPNVGAIV-VVGLGCEGAEPLRIAEEIT------AF 122

Query: 237 SASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSG 296
                 +  ++  G        + +A  + Q+L+ ++ +  P SEL++ M+CGGSD  SG
Sbjct: 123 GKPTSCITIQEEGGTLKCQARGISLARDYAQQLSMQKPQQAPVSELLLAMECGGSDTTSG 182

Query: 297 VTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYL 356
           + +NP+ G ASD L+RCG + + SE TE   A H++  RAV  EVG++L++ +   +   
Sbjct: 183 LASNPSCGVASDKLIRCGGSSILSETTEFIGAEHVMAKRAVTPEVGQQLIDLVVGCEARA 242

Query: 357 NMGKTD-RSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAAT 415
                D R   P+PGN KGGL  + EK+LG + K+G + +  VL     PT  GL    T
Sbjct: 243 KALGEDIRGGQPTPGNIKGGLTTIEEKSLGCMHKAGHAPLQGVLEYADSPTHPGLWIMDT 302

Query: 416 PASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTI 475
           P  D    +  VA G  + +FTTGRGTP G    PVIK+           D +DI+   I
Sbjct: 303 PGQDIESISGMVAGGAQIVIFTTGRGTPAGNPIAPVIKITGNKATWEMMQDNIDIDVSAI 362

Query: 476 ATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAP 521
            +GE +I ++G +++  IL VA+GK  T S+  G HN+ +++  AP
Sbjct: 363 MSGEASITQMGEEIYQEILRVANGK-TTKSEDLG-HNEFSIYKIAP 406


>UniRef50_B0K1I9 Altronate dehydratase n=10 Tax=Firmicutes RepID=B0K1I9_THEPX
          Length = 389

 Score =  468 bits (1204), Expect = e-130,   Method: Composition-based stats.
 Identities = 131/400 (32%), Positives = 204/400 (51%), Gaps = 22/400 (5%)

Query: 120 FEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGC 179
            + Y+  DG  G +N + I  SV C       + +            V G   + +  GC
Sbjct: 3   IKAYKRPDGKYGIRNKVLILPSVGCANETARLISEQ-----------VQGTTYITNPKGC 51

Query: 180 GVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESAS 239
           G      +  +  RT+  ++LNPN  G + ++GLGCE +Q   L                
Sbjct: 52  GQI--GSSVELMHRTLIGLTLNPNVYGTI-IVGLGCETIQAYDLYEEVKKRSN-----KP 103

Query: 240 IVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTA 299
           +  +  ++  G    ++  +++A + ++++++ +RE    S + +   CGGSDA SG+ A
Sbjct: 104 VEVISIQREGGTLKTIQKGIKLARKMVEEMSKIEREEVDISNITLATNCGGSDATSGIAA 163

Query: 300 NPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMG 359
           NP +GY SD+L++ GATV   E TE   A H+L  RA NE+V   LL  ++  +N     
Sbjct: 164 NPTLGYCSDILIKEGATVFLGETTEFIGAEHILARRAKNEKVRNNLLTIVKNLENEFIRL 223

Query: 360 K-TDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPAS 418
               R ANPSPGN KGGL+ + EK+LGSI K G S I EV+  G+ P ++GLI   TP  
Sbjct: 224 GIDVRGANPSPGNIKGGLSTLEEKSLGSIMKGGTSIINEVVRYGEIPKEKGLIIMDTPGY 283

Query: 419 DFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATG 478
           D    T  VA G  + VFTTGRGTP G   +P+IK+    +      D +D++   I  G
Sbjct: 284 DIESVTGMVAGGAQICVFTTGRGTPIGNPIIPLIKITGNKQTYENMSDNIDLDVSDIIEG 343

Query: 479 EETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFN 518
           ++ I+E G  L   I+DV +GK  T ++ +G  ++  ++ 
Sbjct: 344 KKDIKECGEMLLQEIIDVCNGK-LTKAEIYG-FSETCIYR 381


>UniRef50_Q5WIY9 Altronate hydrolase C-terminus n=5 Tax=Firmicutes
           RepID=Q5WIY9_BACSK
          Length = 388

 Score =  462 bits (1189), Expect = e-128,   Method: Composition-based stats.
 Identities = 144/407 (35%), Positives = 212/407 (52%), Gaps = 22/407 (5%)

Query: 116 EGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNH 175
                 G+   DG VG +N + I  ++ C       V K+           VDG V + H
Sbjct: 1   MSLKITGFSRQDGQVGIRNHVLILPTIVCATQAAQNVTKL-----------VDGTVSVIH 49

Query: 176 LYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPV 235
            +GC    +        RT   + LN N  G V+V+GLGCE  Q + +            
Sbjct: 50  QHGCAQVGSDYEQT--FRTYVGMGLNANVYG-VVVMGLGCETHQGKSVAEEIAKKSN--- 103

Query: 236 ESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFS 295
               +  +  + + G      +  +IA + +Q  +  +RE    S+L+VG +CGGSDA S
Sbjct: 104 --KPVELVSIQDYGGTLQATCEAARIATKMVQDASMLEREPIAFSDLIVGTECGGSDACS 161

Query: 296 GVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNY 355
           G++ANPAVGY SD +   G T + +E TE+  A HLL  RA N+ V KR+ E +E  +N 
Sbjct: 162 GLSANPAVGYVSDAIADYGGTSILAETTELIGAEHLLAGRAANDHVAKRVYEVIEAMENR 221

Query: 356 L-NMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAA 414
              MG   R+ NPSPGNK+GGL  + EK+LG+ AK+G   + E++   +RPTK+GL++  
Sbjct: 222 AYQMGVDIRTGNPSPGNKQGGLTTLEEKSLGAAAKAGTRTLHEIVDYAKRPTKKGLVWMD 281

Query: 415 TPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGT 474
           TP  D    T   A G  + +FT+GRGTP G    PVIK+AT T +  +  + +D NAGT
Sbjct: 282 TPGHDIEQLTGMTAGGAQLVLFTSGRGTPTGSPIAPVIKIATNTAMFEKMNENIDFNAGT 341

Query: 475 IATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAP 521
           I  G+E+IE  G +L   +  VASGK+ T ++    H+   ++   P
Sbjct: 342 IIEGKESIESTGERLLAEVAAVASGKR-TKAEILKQHD-FGIWRIGP 386


>UniRef50_Q6L323 Altronate hydrolase n=1 Tax=Picrophilus torridus RepID=Q6L323_PICTO
          Length = 393

 Score =  457 bits (1177), Expect = e-127,   Method: Composition-based stats.
 Identities = 125/405 (30%), Positives = 200/405 (49%), Gaps = 21/405 (5%)

Query: 120 FEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDG-VVGLNHLYG 178
           F GY  ++G  GT+N + I  +V C    V  + +    + L  Y N DG +  LN+ YG
Sbjct: 5   FLGYERSNG-FGTRNHILIIPTVTCSEFTVRRIAR----ESLKYYNNPDGSIKVLNNPYG 59

Query: 179 CGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESA 238
           CG            RT+ N+ +NPN  G V+V+ LGCE +   ++               
Sbjct: 60  CGQT--GEDLEQTTRTLINMGINPNVSG-VLVLSLGCESVDYNKVADEISKY-------K 109

Query: 239 SIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVT 298
            +  L+ + + G    VE  ++  +       + +R       +  G++CGGSD  SG+ 
Sbjct: 110 PVNFLRIQDYGG-LKTVETGIEKIKDLAANAIKEKRNETDLKNITAGLECGGSDFTSGLA 168

Query: 299 ANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLN- 357
           +NP VG  SD ++  G + + SEV E   A HL   RAVNE+V  ++ + +  ++  L  
Sbjct: 169 SNPVVGKVSDWIINNGGSTIISEVPEFIGAEHLYAARAVNEDVRAQIFKTVYAFEKKLKE 228

Query: 358 -MGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATP 416
                 R   P+PGN +GGL  + EK+LG++ KSG + +  VL  G+R +K G     TP
Sbjct: 229 EARVDFRKGQPTPGNMEGGLTTIEEKSLGAVKKSGSAKVSGVLKYGERLSKPGHYLMNTP 288

Query: 417 ASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIA 476
             D    + +VA G  + +FTTGRGTP G +  PVIK+    E   +  D++D +A  I 
Sbjct: 289 GYDVESVSGEVAGGANIVMFTTGRGTPTGNIISPVIKITANEETFKKMEDIIDFDASPIM 348

Query: 477 TGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAP 521
            G+ETIE    +L   +++ A+G + T ++     +  A++   P
Sbjct: 349 RGDETIESASERLKKLLIETANG-RLTKAE-INEQDDFAIYRIGP 391


>UniRef50_C0CW83 Putative uncharacterized protein n=1 Tax=Clostridium asparagiforme
           DSM 15981 RepID=C0CW83_9CLOT
          Length = 387

 Score =  445 bits (1144), Expect = e-123,   Method: Composition-based stats.
 Identities = 123/405 (30%), Positives = 199/405 (49%), Gaps = 23/405 (5%)

Query: 120 FEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGC 179
           F+GY   DG+VG++NL+ +  SV C   V   +V             V G VGL H  GC
Sbjct: 3   FQGYVRPDGTVGSRNLVAVIPSVVCANDVAQAIVAQ-----------VQGTVGLYHHQGC 51

Query: 180 GVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESAS 239
                         T+  +   PN G   +V+ LGCE    ERL+               
Sbjct: 52  CQLPPDLD--RVTETLIGLGCGPNVGA-ALVVSLGCEGTDHERLVEEIA------RTGKP 102

Query: 240 IVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTA 299
           +  ++ ++  G    +   +  A R ++ +  +QR     S++V+ ++CG SD  SG+ +
Sbjct: 103 VEIIRIQQLGGVSKAIAAGIDAASRLVRAIAPQQRREADISKVVLAIKCGASDTTSGMAS 162

Query: 300 NPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMG 359
           N A+GY +D LV  G TV+F E TE   A H+L  RAVN +V  ++ E +   ++     
Sbjct: 163 NCALGYVADKLVDLGGTVVFGETTEFLGAEHILKRRAVNAQVADKIDEIVARMESRAKSL 222

Query: 360 K-TDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRP-TKRGLIYAATPA 417
               R   P+PGN +GGL+++ EK+LG+I KSG   I  V+    R   ++GL    TP 
Sbjct: 223 GCDMRKGQPTPGNIEGGLSSIEEKSLGAIVKSGTRPIQGVMEYTDRVGDRKGLWIKDTPG 282

Query: 418 SDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIAT 477
            +    T    +G  + +F+TGRG P G   +PV+K+           + MDINAG I  
Sbjct: 283 REPEILTGMACTGAQLMMFSTGRGAPQGFPTMPVVKVCGNPITYRNMENDMDINAGLIIE 342

Query: 478 GEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAPV 522
           G+++IE+VG ++F  I++V +G   + ++    ++ + ++   PV
Sbjct: 343 GKKSIEQVGEEVFEKIVEVLNGG-MSKNESLHYYSSIDIYTLGPV 386


>UniRef50_Q1AYL8 D-galactarate dehydratase/Altronate hydrolase-like protein n=2
           Tax=Bacteria RepID=Q1AYL8_RUBXD
          Length = 895

 Score =  443 bits (1141), Expect = e-123,   Method: Composition-based stats.
 Identities = 131/522 (25%), Positives = 212/522 (40%), Gaps = 32/522 (6%)

Query: 20  DTDNVAIIVNDNGLKAGTRFPDG-LELIEHIPQGHKVALLDIPANGEIIRYGEVIGYAVR 78
             DNVAI           R       L   + +GH+ A+  I     ++ +G   G+A+R
Sbjct: 17  PRDNVAIATRRLEAGTRVRCGGSSFSLSHAVLEGHRFAVSRIGEGEALLSWGLPFGWALR 76

Query: 79  AIPRGSWIDESMVV-----------LPEAPPLHTLPLATKV---------PEPLPPLEGY 118
            I  G ++  + ++           LP  P     PL   V          +        
Sbjct: 77  EIRPGEYVCNARILRVLRERRVDLDLPGEPNFRDDPLRPYVLDERNFGPGEQVPRHERPG 136

Query: 119 TFEGY-RNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLY 177
           TF GY R A    GT+N + +             + + +   L    P +DG+V + H  
Sbjct: 137 TFMGYGRGAARGAGTRNHIVVLGLTSRTGPYARALERRLAG-LAAGVPGLDGIVAVAHTE 195

Query: 178 GCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVES 237
           G G         + +RT+    ++PN  G V+ +  G   L    L     + +  P+  
Sbjct: 196 G-GEDRPPNNLGLLLRTLAGFMVHPN-AGAVLAVDDGRGALTGGALRRYMKE-RGYPLRE 252

Query: 238 ASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGV 297
                +       F   +    +     L +    +R   P S L + +QCGGSDAFSGV
Sbjct: 253 VPHRFMTLR--GSFAGELRRGERAVRGWLGEAGSARRSPQPLSRLRLALQCGGSDAFSGV 310

Query: 298 TANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLN 357
           +ANP V + +  L+R G +   +E  E+  A   +     +    +R L+ +E +   + 
Sbjct: 311 SANPLVAWVARELLRHGGSANLAETDELIGAERYVLENVRDLATARRFLQTVERFRELVG 370

Query: 358 MGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVE-VLSPGQRPTKRGLIYAATP 416
                   NPS GN   GL N+  K++G+  K      ++ V+    R    G  +  +P
Sbjct: 371 RHGHTAEGNPSGGNNYRGLYNIAIKSIGAARKKDPGVRLDYVIPYAGRMDAPGYYFMDSP 430

Query: 417 ASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIA 476
            +D      QVASG  V  FTTG G+      VP IK+ + T       D MD+NAG   
Sbjct: 431 GNDLESVAGQVASGANVIFFTTGNGSITNFPFVPTIKVVSTTGRYRLLADEMDVNAGAYL 490

Query: 477 TGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFN 518
            G   +EE+G   F   + VASG++ T  ++ G H+Q++++ 
Sbjct: 491 DG-TPMEELGRDAFDLAVRVASGER-TAGERAG-HSQVSIWR 529



 Score = 95.4 bits (236), Expect = 4e-18,   Method: Composition-based stats.
 Identities = 63/397 (15%), Positives = 122/397 (30%), Gaps = 81/397 (20%)

Query: 117 GYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHL 176
           G++FEG R  +G    + +  I  +  C   +   +   +   L      +   V L H 
Sbjct: 563 GFSFEGVRKGEGYAADR-VGLIMPTSLCAGQIALIIAGRLNG-LGVGEGKLSRFVALPHT 620

Query: 177 YGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVE 236
            GCGV+    +  +  RT+     +P+ G   +++  GCEK   +       +    P +
Sbjct: 621 EGCGVSG-GHSERLYARTVLGYLSHPSVGA-ALLLEHGCEKTHNDYFRARLAERGLDPGD 678

Query: 237 SASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGG--SDAF 294
                    +   G + +V  +       L+ + + +RE      L VG+   G   +  
Sbjct: 679 FG---WASIQLDGGIERVVRRVEGWFGEALEGMGEMEREPAGPEHLRVGLHAEGPLPEGT 735

Query: 295 SGVTANPAVGYASDLLVRCGATVMFSE-VTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYD 353
           +G  A  A+      +   G TV+  E    +      +  RA                 
Sbjct: 736 AGALAQLAL-----RVAASGGTVVIPERSPALEGLRGRVPLRA----------------- 773

Query: 354 NYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYA 413
                                    +           G+      L   + PT       
Sbjct: 774 ------------------------TLA---------YGQRPAAPGLHVMEAPT------- 793

Query: 414 ATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAG 473
                     T   A+G+ V +             VP+++ ++  E   R  + +D+   
Sbjct: 794 ---GDWMEIATGLGAAGVEVMLAHVAGRPLRAHRLVPLLQASSDAETLYRCGEDLDV--- 847

Query: 474 TIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGL 510
               GE +      +    +L+ ASG++     + G 
Sbjct: 848 -ALRGEPSGWRAALE--RAVLEAASGRRFPRLARQGY 881


>UniRef50_D1Y193 Galactarate dehydratase n=1 Tax=Pyramidobacter piscolens W5455
           RepID=D1Y193_9BACT
          Length = 408

 Score =  438 bits (1126), Expect = e-121,   Method: Composition-based stats.
 Identities = 123/411 (29%), Positives = 200/411 (48%), Gaps = 28/411 (6%)

Query: 116 EGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNH 175
              TF GYR +DG+VG +N L I  SV C    V+ +   +            G V + H
Sbjct: 1   MTMTFNGYRRSDGTVGVRNHLAIIPSVFCANRTVERIAAQL-----------PGSVPIRH 49

Query: 176 LYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPV 235
             GC          +  RT+  +  +PN G  V+VIGLGCE+  P  L         +  
Sbjct: 50  AVGCSQV--GLDLELTARTLKALGTHPNVGA-VLVIGLGCERFPPRELEEA------VRK 100

Query: 236 ESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFS 295
               +     ++  G  + ++  ++   +    L +++R  CP SEL VG +CGG+DA S
Sbjct: 101 SGRPVACFVIQEEGGTTNTIKHAVEAGRKMFASLAEQRRVPCPLSELFVGTKCGGTDATS 160

Query: 296 GVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNY 355
           G+ ANPAVG   D LV  G + + SE+ E+    H+L  RAV++EV  ++ + +   ++ 
Sbjct: 161 GLAANPAVGEMVDKLVAQGGSAILSEMNELLGTEHILARRAVSKEVADKVYKAIYEIEDV 220

Query: 356 LNMG-----KTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPT--KR 408
           L  G        R+   SPGN  GG++++VEKALG + KSG   IV+V+     P   K+
Sbjct: 221 LRSGIDMRLGAKRNQLISPGNADGGVSSIVEKALGGMHKSGTCPIVDVIDYATPPEKGKK 280

Query: 409 GLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLM 468
           GL      + D    T ++  G  +  FTTGRG+P G    PV+K+    +      ++ 
Sbjct: 281 GLFLMKYESHDGEVTTGEIGCGAQIVAFTTGRGSPTGHPIAPVVKITGNEKTYKAMSEMF 340

Query: 469 DINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNP 519
           D +A  I +  +++E+ G  L   ++ VA G++ T +++ G  + + +   
Sbjct: 341 DFDASGIISRGDSLEDTGRALLDLVIRVADGER-TQAEKTGDDSLMCIARR 390


>UniRef50_D1Y174 D-galactarate dehydratase (GalcD) n=3 Tax=Bacteria
           RepID=D1Y174_9BACT
          Length = 386

 Score =  431 bits (1109), Expect = e-119,   Method: Composition-based stats.
 Identities = 129/394 (32%), Positives = 191/394 (48%), Gaps = 21/394 (5%)

Query: 120 FEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGC 179
           F GY+  +G  G +N + I  +  C +     V   +                +N ++  
Sbjct: 3   FWGYKRQEGRAGIRNHVLILPTCACGSESARIVASEVRG-------------AVNIIFNT 49

Query: 180 GVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESAS 239
           G +  A    +  + +   + NPN  G V++IGLGCE +   +L      +         
Sbjct: 50  GCSDVAANTAMSQKVLMGFACNPNVYG-VVIIGLGCETVGHAQLREKIRGM-----TGKP 103

Query: 240 IVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTA 299
           +VS   ++  G    +E  ++ A         +Q+E C  S L++G++CGGSDA SG+ +
Sbjct: 104 VVSFGIQEEGGTLKTIEKAVRAARDMAAAAAMQQKERCDMSNLLLGIECGGSDATSGIAS 163

Query: 300 NPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMG 359
           NPAVG  SDLLV  GA+ + SE  E   A H++  RA   E+  +++E    Y+ +L   
Sbjct: 164 NPAVGELSDLLVDLGASTIMSESIEWIGAEHVVARRAATPELHNKIIEICRDYEEHLKAA 223

Query: 360 KTD-RSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPAS 418
             D R+  P+PGNK GGL+ + EK+LG I K G   IVEVL+  +RPTK G I   T   
Sbjct: 224 GQDCRAGQPTPGNKAGGLSTLDEKSLGCIRKGGTRPIVEVLAQAERPTKHGAIVMDTAGY 283

Query: 419 DFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATG 478
           D    T  VA G    +FTTGRGTP G   VPV+K+           D MD++   I  G
Sbjct: 284 DISSVTSMVAGGCNAVIFTTGRGTPTGNAIVPVLKVTANARTYRMMDDNMDVDLSGIIKG 343

Query: 479 EETIEEVGWKLFHFILDVASGKKKTFSDQWGLHN 512
             T  E G +L   I DV +GK  T ++ +G  +
Sbjct: 344 TTTYRESGRELLEIIGDVCNGK-MTKAEAYGFSD 376


>UniRef50_D2PZR0 D-galactarate dehydratase/Altronate hydrolase domain protein n=1
           Tax=Kribbella flavida DSM 17836 RepID=D2PZR0_9ACTO
          Length = 923

 Score =  429 bits (1103), Expect = e-118,   Method: Composition-based stats.
 Identities = 120/520 (23%), Positives = 210/520 (40%), Gaps = 34/520 (6%)

Query: 20  DTDNVAIIVNDNGLKAGTRFPDG-LELIEHIPQGHKVALLDIPANGEIIRYGEVIGYAVR 78
             DN AI            F    + L   + +GH++ +  +     +  +      A+R
Sbjct: 29  PGDNAAICSRRLDAGTVVDFAGTPVTLPHTVLEGHRIVVRPVRTGEALTSWQTPFARALR 88

Query: 79  AIPRGSWIDESMVV----------LPEAPPLHTLPLATKVPEPLPPLEGY---------T 119
            +  G ++     +          LP AP     PL     +      G          T
Sbjct: 89  DLAVGDYVCTPTSLAAVSARGVDGLPAAPSASNEPLDPYELDENAVHLGRQVTSVEQPGT 148

Query: 120 FEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGC 179
           F GY  A G  GT+N + +  +    +G V  + +  +          DGVV + H  G 
Sbjct: 149 FLGYPRAQGPAGTRNHVVLLATSSRSSGFVTELARRFDGAAAG-----DGVVPVAHTEGA 203

Query: 180 GVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESAS 239
                    ++        +LNPN G  V+V+    E L   + +      +  P     
Sbjct: 204 EQGTPNNLTLLLATL-AGFALNPNVGA-VLVVDTE-EDLVSGQAIRDFMAERGYPELQVP 260

Query: 240 IVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTA 299
                 +   GF+  +     + E  L  ++ +QR   P ++L + +QCGGSDAFSGVTA
Sbjct: 261 HAFFTRQA--GFEQDLTAAGALIEPWLPVVDAQQRTEVPLADLWIALQCGGSDAFSGVTA 318

Query: 300 NPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMG 359
           NP  G  +  ++R G T + +E  E+  A   +     +    +R L  ++ +   +   
Sbjct: 319 NPLSGAVAREVIRHGGTAVLAETDELIGAEGYVLKNVRDLPTARRFLRTVQAFKERVGWH 378

Query: 360 KTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVE-VLSPGQRPTKRGLIYAATPAS 418
                 NPS GN   GL N+V K++G+  K  +   ++ V+   +     G ++  +P +
Sbjct: 379 GHTAEGNPSGGNVYRGLYNIVLKSVGAARKLDRDVRLDHVIDYAEPVPGPGFVFMDSPGN 438

Query: 419 DFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATG 478
           D      +VASG  +  FTTG G+      VP IK  T +   +     MD++AG   TG
Sbjct: 439 DLESIAGEVASGCNLIFFTTGNGSITNFPFVPTIKFVTTSARYDLLEAEMDVDAGRYLTG 498

Query: 479 EETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFN 518
             +++ +  +     + VASG+     ++ G H+Q++++ 
Sbjct: 499 -TSMDALTAETLDLTVRVASGEPS-AGERAG-HSQVSIWR 535



 Score = 93.9 bits (232), Expect = 1e-17,   Method: Composition-based stats.
 Identities = 55/328 (16%), Positives = 92/328 (28%), Gaps = 64/328 (19%)

Query: 137 GITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIH 196
            I  +  C   +   +    E +       V  +V L H  GCG +  A       RT+ 
Sbjct: 604 LILPTSLCSGQIALRLAGRAELE-KWAGDAVTRMVALPHTEGCGSSGGASEET-FARTLL 661

Query: 197 NISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVE 256
              L+PN     +++  GCEK   +       +  A P           +   G  ++ +
Sbjct: 662 GYLLHPNTR-MALLLEHGCEKTHNDYFRAKLVEAGADPSRFG---WASIQADGGLDAVTD 717

Query: 257 DILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGAT 316
            +          L   Q+       L V ++  G    S  TA  A+      LV  G +
Sbjct: 718 RVRDWFSSF--DLPAPQQVEGDVGALTVALEARG--PLSDDTAE-AMALIGHELVAAGGS 772

Query: 317 VMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGL 376
           V+ S                                  + +         P P       
Sbjct: 773 VVLS---------------------------SRGALLAHDSFRVAAFGTTPGP------- 798

Query: 377 ANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASD-FVCGTQQVASGITVQV 435
                             +   L+ GQR    G      P +D     T   A G+   +
Sbjct: 799 ------------------VAPTLAHGQRLAAPGWHVMRMPGTDWMETATGFGAGGVQQIL 840

Query: 436 FTTGRGTPYGLMAVPVIKMATRTELANR 463
                GT      VPV+++++  E   +
Sbjct: 841 AHVAGGTLSAQRFVPVVEISSDPETVAK 868


>UniRef50_A9V9F3 Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9V9F3_MONBE
          Length = 958

 Score =  427 bits (1099), Expect = e-118,   Method: Composition-based stats.
 Identities = 129/508 (25%), Positives = 201/508 (39%), Gaps = 53/508 (10%)

Query: 55  VALLDIPANGEIIRYGEVIGYAVRAIPRGSWIDE-------------------------- 88
           +AL  I    +I  +G   G A+  +  GS++                            
Sbjct: 41  LALDFIAKGTQITSWGLPFGIALMDLAPGSYLCNLKSLATFADRHSKLNLPSEPTFRNAP 100

Query: 89  ---SMVVLPE---APPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVGTKNLLGITTSV 142
                V       APP      A   P PL    G+   G R A    GT+N + I    
Sbjct: 101 FTRHTVAQQNFSPAPPTKRDESAAATPAPLTTFMGFPRGGNRGA----GTRNYVVILGIS 156

Query: 143 HCVAGVVDYVVKII-----ERDLLPKYPNVDGVVGLNHLYGCGVA----INAPAAVVPIR 193
              AG    + +       +   L      DGVV + H  G   A     N       +R
Sbjct: 157 SRAAGFARALERQFTHTLEQARTLQGQATCDGVVAVAHTEGGLDAKLTTDNENNVEKVLR 216

Query: 194 TIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQS 253
            +   +++PN G  V+ +  G E +    +L         P++     +L  +     ++
Sbjct: 217 VLAGFAVHPNVGA-VLFLDHGDEVVTTRHVLEYIRAHD-YPLDDVPYRALSLKNQTMKEA 274

Query: 254 MVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRC 313
           M +   ++ E    +  Q QR       L    QCGGSDAFSG++ANP  G+ +  LV  
Sbjct: 275 MHQ-ATELVEELYLQAQQHQRVAVGVEHLCFAQQCGGSDAFSGISANPLAGWMARELVAQ 333

Query: 314 GATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKK 373
           G + + +E  E+  A   +  R  + +     L+ ++ Y  Y N        NPS GN  
Sbjct: 334 GGSAVLAETDELIGAESYVLQRVRDYDTADHFLQLVDRYYRYTNRRGHSPEGNPSGGNLY 393

Query: 374 GGLANVVEKALGSIAKSGKSAIVE-VLSPGQR--PTKRGLIYAATPASDFVCGTQQVASG 430
            GL N+  K+ G+  K      ++ VL  GQR  P   G  +  +P +D      QVA+G
Sbjct: 394 RGLYNITLKSAGAAMKKLPDVRLDHVLEYGQRLQPEGHGYAFMDSPGNDLESIAGQVAAG 453

Query: 431 ITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLF 490
             + VFTTG G+      VP IK+ T T+      D MD+NAG    GE ++ ++G + +
Sbjct: 454 CNMIVFTTGNGSVTNFPFVPTIKVLTTTKRYQLLSDDMDVNAGRFLDGEVSLSQLGREAY 513

Query: 491 HFILDVASGKKKTFSDQWGLHNQLAVFN 518
              +  ASG   T  +  G H Q+ ++ 
Sbjct: 514 QLFVRAASGTP-TKGELAGHH-QVQIWR 539



 Score = 78.4 bits (192), Expect = 6e-13,   Method: Composition-based stats.
 Identities = 31/184 (16%), Positives = 63/184 (34%), Gaps = 8/184 (4%)

Query: 145 VAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNF 204
              +   +         P +  +   V L H  GCG +       + +RT+ + + +P  
Sbjct: 637 ADKIARQLNDRKAAQNAPIFAGLSRFVALPHTEGCGHSSGDHE-SLVMRTLSSYAAHP-M 694

Query: 205 GGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQIAER 264
            G V+++  GCEK    R      +  ++ ++         +   G   +   + Q+ E+
Sbjct: 695 AGAVVMLEHGCEKTHNGRFQQLLSEDPSVSLDR--CAFASIQLDGGLNKVTSRVEQLLEQ 752

Query: 265 HLQKLNQRQ-RETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVT 323
                     R+    S + +G+        S   A   +G     +   G TV+ +   
Sbjct: 753 LELSSTSVPVRQPAAVSHIRIGILATTPLPTSVQAA---LGLVVAAVTLEGGTVVLAGSH 809

Query: 324 EVRD 327
            VR 
Sbjct: 810 VVRG 813


>UniRef50_A8RT57 Putative uncharacterized protein n=1 Tax=Clostridium bolteae ATCC
           BAA-613 RepID=A8RT57_9CLOT
          Length = 412

 Score =  415 bits (1067), Expect = e-114,   Method: Composition-based stats.
 Identities = 114/415 (27%), Positives = 179/415 (43%), Gaps = 39/415 (9%)

Query: 116 EGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNH 175
             Y++ GY   +G++G +N + +  +V C + V   +V+      L   P  + VVG + 
Sbjct: 12  REYSWMGYVRKNGAMGIRNKVLVIYTVECASFVAREIVR------LAGDPETE-VVGFS- 63

Query: 176 LYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPV 235
               G   N  A    +R +  +  +PN G  V+ +GLGCE +QPE L            
Sbjct: 64  ----GCTDNEYA----VRLLIALIRHPNVGA-VLTVGLGCEYVQPEWLADIAGK------ 108

Query: 236 ESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFS 295
           E      +  ++  G +  +E  L +     ++L   +R+     +L++G +CGGSD  S
Sbjct: 109 EGKEAAWMFIQQEGGTRKTIEKGLAVVGLMRERLKDTKRKPMGIRDLIIGAECGGSDYTS 168

Query: 296 GVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNY 355
           G+  N  VG   D L   G T +F E+ E      +L  RA NE   + + +    YD  
Sbjct: 169 GLAGNVVVGRFFDRLTDLGGTAIFEEIVEAIGLKEMLVGRAANERARQEIGDT---YDKA 225

Query: 356 LNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAA- 414
           L   K+ R  + SPGN  GGL+ + EK++G++ KSG   I  VL  G +P   GL     
Sbjct: 226 LEYCKSVRQYSVSPGNFAGGLSTIEEKSMGALIKSGSRPIEGVLKVGVKPPHPGLWLLDS 285

Query: 415 TPA-----------SDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANR 463
           TP            +D        A    +    TGRG   G   VP IK+   +     
Sbjct: 286 TPDPYWMQFGITNPNDSEGLMDLAACHSHIVFLVTGRGNVVGSAVVPCIKITGNSATYRA 345

Query: 464 WFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFN 518
             + MD +AG +  G  + +E+  +L     +VASG K   S+  G       + 
Sbjct: 346 MEEDMDFDAGPVLEGRCSQDEMAQRLLKMAAEVASGTKS-KSEALGHKEYFIPYK 399


>UniRef50_B8FML6 Altronate dehydratase n=1 Tax=Desulfatibacillum alkenivorans AK-01
           RepID=B8FML6_DESAA
          Length = 386

 Score =  408 bits (1048), Expect = e-112,   Method: Composition-based stats.
 Identities = 132/400 (33%), Positives = 198/400 (49%), Gaps = 23/400 (5%)

Query: 119 TFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYG 178
           +F GY   DGSVG +N + +  SV                        V GVV L H  G
Sbjct: 3   SFMGYGREDGSVGVRNYVAVIPSVA-----------CAAPVAAAIARAVPGVVPLLHGMG 51

Query: 179 CGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESA 238
           CG       A +  RT  N+  NPN G  V+++GLGCE      ++       A  +   
Sbjct: 52  CG--RGGSDADMHTRTFQNLCKNPNVGA-VIIVGLGCE------VVNAEGMALAAAMAGR 102

Query: 239 SIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVT 298
               L  +   G +      + IA+  + ++  ++R+  P  +L +G++CGGSDAFSGVT
Sbjct: 103 PHARLMIQAEGGSRKTTAKGIGIAKDFMTQIQVQERKPFPLDKLTLGLECGGSDAFSGVT 162

Query: 299 ANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYD-NYLN 357
           ANPAVG ASD LV  G  V+ +E TE+    H+L  R+ N E+ +++   +   +     
Sbjct: 163 ANPAVGRASDWLVAKGGKVILTETTEMIGTSHILERRSANPEIAEQIKNLISSVEAKTYE 222

Query: 358 MGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPA 417
           +         SPGN  GG++++ EKALG I K G + I +V+   + PT+ GL     P 
Sbjct: 223 VLGPIAKMIMSPGNMDGGMSSIREKALGCIIKGGTTPINQVVDYAEIPTQPGLSIMHGPG 282

Query: 418 SDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIAT 477
            D    T   ASG  V VFTTGRG P G   VPV+K+A+ + +     D MD+NAG I  
Sbjct: 283 YDAESLTGLAASGAQVIVFTTGRGNPIGFPIVPVVKVASTSRMFQSMEDDMDLNAGAILE 342

Query: 478 GEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVF 517
           G+ +++++G  +   ILD  +G++ T ++       L V+
Sbjct: 343 GK-SLDQMGEDVVQCILDAVNGRR-TKAEINEQDGVLCVY 380


>UniRef50_C5EFV8 Hydrolase n=1 Tax=Clostridiales bacterium 1_7_47FAA
           RepID=C5EFV8_9FIRM
          Length = 385

 Score =  405 bits (1040), Expect = e-111,   Method: Composition-based stats.
 Identities = 108/406 (26%), Positives = 181/406 (44%), Gaps = 25/406 (6%)

Query: 116 EGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNH 175
              TF GY   DG  G +N + I ++      +   V ++           ++G + +  
Sbjct: 1   MRKTFMGYARPDGRYGVRNYVAIISTADNSNFIARRVAQM-----------INGTIPVCP 49

Query: 176 LYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPV 235
            +G G         + I+T+  +  NPN    V+V                      I  
Sbjct: 50  CFGRGEIGPDMD--LHIKTMGGMGANPNVHSAVVV---------SLEPALAEKIAAVIRA 98

Query: 236 ESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFS 295
                 +   ++  G     E  ++ A R + + +  QR       L +G++CGGSD  S
Sbjct: 99  TGKKAETFSMDECGGSIGCTEQAVRAARRLIIEASMEQRVEVGIEHLHLGVECGGSDTTS 158

Query: 296 GVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNY 355
           G+ +NPA G  +D LV  G TV+ SE TE   A ++L  RAV  E+G+R+++ + WY++Y
Sbjct: 159 GLVSNPATGLVADQLVDAGGTVILSETTEWMGAENILLKRAVTPELGERIVKAIRWYEDY 218

Query: 356 LNM-GKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAA 414
           +   G      NP+P N KGGL+ + EKALGSI K G   I ++L+  + P + G+    
Sbjct: 219 IKSIGVDLNGFNPAPDNIKGGLSTIEEKALGSIKKGGTRPIQDMLTCSEAPGRPGMYLMD 278

Query: 415 TPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGT 474
            P       T    +G  + +F+TG+G P G    P IK+        +  + +D++   
Sbjct: 279 APTGGVENTTALAGAGCQLIIFSTGKGNPLGNPIAPTIKVTGNERTIGKSGENIDVDLSA 338

Query: 475 IATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPA 520
           + T +  I+  G  L+  ++D A GK  T ++  G   ++AV    
Sbjct: 339 VITEDMDIQAAGNILYEKMIDHADGKLTT-AEALGDL-EIAVTRIG 382


>UniRef50_B5IW17 D-galactarate dehydratase / Altronate hydrolase, C terminal domain
           superfamily n=1 Tax=Thermococcus barophilus MP
           RepID=B5IW17_9EURY
          Length = 394

 Score =  404 bits (1039), Expect = e-111,   Method: Composition-based stats.
 Identities = 107/414 (25%), Positives = 191/414 (46%), Gaps = 33/414 (7%)

Query: 119 TFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYG 178
             +G+R  +G  G +N + + +SV C       + +              G + +    G
Sbjct: 5   EIKGWRRENGDFGIRNHIVVLSSVACANHAALEIARRT------------GAIPIIQEEG 52

Query: 179 CGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESA 238
               +        +R + N+  +PN     +V+GLGCE +   +L               
Sbjct: 53  -ACGMFGEDRKRFLRCMANVGSHPNVAWT-LVVGLGCEGIDAHQLADEISKR------GR 104

Query: 239 SIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVT 298
           +  SL  ++  G    VE  +++  R  + L   +RET    ELV+G++CG SD  SG+ 
Sbjct: 105 NAESLLIQEL-GMDKTVEKGIELVNRAKENLTP-RRETAGVEELVIGLKCGASDYTSGLI 162

Query: 299 ANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEME-WYDNYLN 357
           +NP+VG A D+L+  G T + +E  E+  A  +L  RA ++EV +  L  ++   ++   
Sbjct: 163 SNPSVGKAVDILIEYGGTAIITERLELVGAEQILARRAKSKEVAEDFLRRIKKAVEDVNK 222

Query: 358 MGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPA 417
            G     + PS GN KGGL  + EK+LG++ K+G + +   L  G++P  RGL +   P 
Sbjct: 223 RGVDWIGSQPSMGNIKGGLTTIEEKSLGAVKKAGNAQLEGCLDYGEKPKGRGLYFMDGPG 282

Query: 418 SDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAG---- 473
            D    +  + +G  + +FTTG GT  G    PVIK+      A +  D +D++      
Sbjct: 283 YDVKAVSGLMCAGSHIILFTTGLGTYLGSPVSPVIKITGNPTTARKLRDAIDVDLSILLE 342

Query: 474 TIATGEETIEEV----GWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAPVT 523
            I + + +++E+    G  +   I+ VA+GK  T +++   H + ++     + 
Sbjct: 343 EIISRDASLDEILEIGGRMILEEIVRVANGK-LTKAEK-SQHIEFSIELTGIIA 394


>UniRef50_D2S1M0 Altronate dehydratase n=1 Tax=Haloterrigena turkmenica DSM 5511
           RepID=D2S1M0_9EURY
          Length = 395

 Score =  402 bits (1033), Expect = e-110,   Method: Composition-based stats.
 Identities = 135/405 (33%), Positives = 198/405 (48%), Gaps = 24/405 (5%)

Query: 119 TFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYG 178
           TF GYR  DG +G +N + +  +    + V D +                 V    H  G
Sbjct: 3   TFSGYRREDGRIGVRNRVAVLPTSVAASAVADRIAANGGPR----------VTATPHQMG 52

Query: 179 CGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESA 238
                  PA     R +  I  NPN GG  +V+ LG E          +     I     
Sbjct: 53  TEQ--PEPARRRTERVLAGIGRNPNVGG-ALVVELGTEG------ADASAIADEIAAADT 103

Query: 239 SIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVT 298
            + +L      G ++ V+   +  +  L++  + + ET  ASELV G++CGGSDA SG+ 
Sbjct: 104 PVETLSIRDAGGTRATVDRGRETVDALLEEAARARLETADASELVFGVECGGSDATSGIA 163

Query: 299 ANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLN- 357
           ANPAVG A D LV  G T  FSE  E   A H+L  R V+E V +RL+E +E  ++  + 
Sbjct: 164 ANPAVGNACDRLVEAGGTSCFSETPEFIGAEHILAERCVDESVRERLIECVERRESVADL 223

Query: 358 MGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQR-PTKRGLIYAATP 416
           MG   R   P+PGN++GGL  + EK+LG+IAK G + I +V+      P   GL+   TP
Sbjct: 224 MGVDLRGTQPTPGNQEGGLTTIEEKSLGAIAKGGTTPIRDVIDYADPLPIGGGLVVMDTP 283

Query: 417 ASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIA 476
             D      +VA G  V  FTTGRG+  G    PVIK+    + A R    MD++A T+ 
Sbjct: 284 GYDVESVVGKVAGGAQVIAFTTGRGSTTGNPIAPVIKVTGNPQTAERMATNMDVDASTVL 343

Query: 477 TGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAP 521
            GE ++E VG +++  +L VA G + T +++ G+  + A+    P
Sbjct: 344 DGE-SVEAVGERVYETLLSVADGTR-TEAERRGM-AEFAINELQP 385


>UniRef50_B1M8U1 Altronate dehydratase n=55 Tax=root RepID=B1M8U1_METRJ
          Length = 426

 Score =  402 bits (1033), Expect = e-110,   Method: Composition-based stats.
 Identities = 119/438 (27%), Positives = 182/438 (41%), Gaps = 30/438 (6%)

Query: 87  DESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVGTKNLLGITTSVHCVA 146
            E         P      A             TF G+R  +G VG +N + +        
Sbjct: 10  HEIATPFVGGAPDQFATKALATERASENYTAATFMGWRRENGRVGVRNHVVLLPLDDLSN 69

Query: 147 GVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGG 206
              + V             NV G + L H YG           +  RT+  I  NPN   
Sbjct: 70  AACEAVAN-----------NVKGTMALPHAYGRLQF--GEDLDLHFRTLIGIGSNPNVAA 116

Query: 207 EVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQIAERHL 266
            V++   G E     R++ G             +V    E H G  ++V      A+R +
Sbjct: 117 VVVI---GIEDQWTNRVVEGIA------RTGKPVVGFGIEGH-GDIAIVAKASYQAKRFV 166

Query: 267 QKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVR 326
           Q   + QRE CP ++L V  +CG SD  +G+ + P VG   D L+  G   +F E +E+ 
Sbjct: 167 QWATELQREECPIADLWVSTKCGESDTTTGLASCPTVGNMYDKLIPHGIYGVFGETSEIT 226

Query: 327 DAIHLLTPRAVNEEVGKRLLEEMEWY-DNYLNMGKTD--RSANPSPGNKKGGLANVVEKA 383
            A HL   RA++ EV  +     + Y D+ +   KTD    + P+ GN  GGL  + EKA
Sbjct: 227 GAEHLCRERAISPEVSDKWYAMWKAYQDDVIEAHKTDDLSDSQPTKGNIAGGLTTIEEKA 286

Query: 384 LGSIAKSGKSA-IVEVLSPGQRPTK-RGLIYAATPASDFVCGTQQVASGITVQVFTTGRG 441
           LG++ K G     ++ L P + PTK  GL +  T ++   C T   A+G  V  F TG+G
Sbjct: 287 LGNLEKIGHECRFIDALQPAEAPTKGPGLYFMDTSSAAAECVTLMAAAGYVVHTFPTGQG 346

Query: 442 TPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKK 501
              G   VPVIK+           + +D++   + T E TI + G  L   ++  A+G +
Sbjct: 347 NVIGNPIVPVIKITGNPRTVRTMGEHIDVDVSGVLTREMTIPQAGDALIDMVVRTANG-R 405

Query: 502 KTFSDQWGLHNQLAVFNP 519
            T ++  G H +  +   
Sbjct: 406 LTAAESLG-HREFVMTKL 422


>UniRef50_Q13SA4 Altronate dehydratase n=48 Tax=Bacteria RepID=Q13SA4_BURXL
          Length = 450

 Score =  402 bits (1032), Expect = e-110,   Method: Composition-based stats.
 Identities = 125/437 (28%), Positives = 186/437 (42%), Gaps = 31/437 (7%)

Query: 101 TLPLATKVPEPLPPLEGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDL 160
           T+   T V  P    +  T +GY   DG  G +N++ +   V C   V   +V      L
Sbjct: 10  TIMTDTSVASPSAASQQPTLQGYLRRDGRKGIRNVVAVAYLVECAHHVAREIVTQFREPL 69

Query: 161 LPKYPNVDGVVGLNHLYGC-GVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQ 219
                         HL G  G   N+ A  +  R    ++ +PN G  V+ + LGCE + 
Sbjct: 70  DAFDDPSAEREPPVHLIGFPGCYPNSYAEKMLER----LTTHPNVGA-VLFVSLGCESMN 124

Query: 220 PERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPA 279
              L      V  +      +  L  ++  G +S ++  +       ++L  +Q+     
Sbjct: 125 KHYL------VDVVRASGRPVEVLTIQEKGGTRSTIQYGVDWIRSARKQLAAQQKVPMAL 178

Query: 280 SELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNE 339
           SELV+G  CGGSD  SG+TANPAVG A D L+  GAT +F E  E+      +  RA   
Sbjct: 179 SELVIGTICGGSDGTSGITANPAVGRAFDHLIDAGATCIFEETGELVGCEFHMKTRAARP 238

Query: 340 EVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVL 399
           E+G+ ++  +     Y ++      A    GN  GGL    EK+LG+ AKSG S IV ++
Sbjct: 239 ELGEEIVACVAKAARYYSILGHGSFAV---GNADGGLTTQEEKSLGAYAKSGASPIVGIV 295

Query: 400 SPGQRPTKRGLIYAA-----------TPASDFVCGTQQVASGITVQVFTTGRGTPYGLMA 448
            PG  P   GL                  SD     + +A G  V +FTTGRG+  G   
Sbjct: 296 KPGDIPPTGGLYLLDVVPDGEPRFGFPNISDNAEIGELIACGAHVILFTTGRGSVVGSAI 355

Query: 449 VPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQW 508
            PVIK+             MD++AG I  G  T++EVG ++F   + V+ G     S+  
Sbjct: 356 SPVIKVCANPATYRNLAGDMDVDAGRILEGRGTLDEVGREVFEQTVAVSRGAAS-KSETL 414

Query: 509 GLHNQLAVFN----PAP 521
           G    +  +       P
Sbjct: 415 GHQEFILTYKTFEPVGP 431


>UniRef50_C9KKM7 Hydrolase, UxaA family n=1 Tax=Mitsuokella multacida DSM 20544
           RepID=C9KKM7_9FIRM
          Length = 352

 Score =  400 bits (1028), Expect = e-110,   Method: Composition-based stats.
 Identities = 122/342 (35%), Positives = 177/342 (51%), Gaps = 8/342 (2%)

Query: 172 GLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQ 231
            +N ++  G +  A    +  + +   + NPN  G V++IGLGCE +    L      + 
Sbjct: 8   AVNIVFNTGCSDVAANTAMSQKVLTGFACNPNVYG-VVIIGLGCETVPHAALREKIQKM- 65

Query: 232 AIPVESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGS 291
                S  +VS   +   G    +E  ++ A    Q+   +Q+E  PASEL++G++CGGS
Sbjct: 66  ----TSKPVVSFGIQDEGGTLKTIEKAVRAARDMAQQAGMQQKELFPASELLLGIECGGS 121

Query: 292 DAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEW 351
           DA SG+  NPAVG  SD+LV  GA+ M SE  E     H+L  RA   E+ + ++   E 
Sbjct: 122 DATSGIACNPAVGELSDILVDMGASAMMSESIEWIGGEHVLAKRAATPEIQREIIRVCEE 181

Query: 352 YDNYLNMGKTD-RSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGL 410
           Y+ +L     D R+  P+PGNK GGL+ + EK+LG I K G   IVEVL    RPTKRG 
Sbjct: 182 YEKHLAGAGQDCRAGQPTPGNKAGGLSTLDEKSLGCIRKGGTRPIVEVLEQAVRPTKRGA 241

Query: 411 IYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDI 470
           +   T   D    T   A+G  V +FTTGRGTP G   VPV+K+           D MD 
Sbjct: 242 LVMDTAGYDISSVTSMAAAGCQVIIFTTGRGTPTGNAIVPVLKVTANARTYRCMEDNMDA 301

Query: 471 NAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHN 512
           +   I  GE+T ++ G +L   I   A+G + T ++ +G  +
Sbjct: 302 DLSAIVRGEKTYQQAGRELVDAIAATANG-RLTKAEAFGFSD 342


>UniRef50_Q0KC73 D-Galactarate dehydratase n=4 Tax=Burkholderiales
           RepID=Q0KC73_RALEH
          Length = 386

 Score =  397 bits (1019), Expect = e-109,   Method: Composition-based stats.
 Identities = 106/391 (27%), Positives = 177/391 (45%), Gaps = 24/391 (6%)

Query: 116 EGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNH 175
              TF GY   +G+VG +N + + + +     V   + + +   +      V G      
Sbjct: 3   MTATFLGYPRENGAVGVRNWVAVVSVMDNCNPVTRTIARTVGGCIPVTTLFVRGQF---- 58

Query: 176 LYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPV 235
                             ++  +  NPN    V+++GL           +  +  + I  
Sbjct: 59  ---------GADLDFAFESLAGLGRNPNIAA-VLLVGL--------EESSTEEVARRIRS 100

Query: 236 ESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFS 295
               +  +  +   G  + + +  + A R     ++ +R  CP S LV+G++CGGSD  S
Sbjct: 101 TGKPVECVHLQPD-GTVACIAEGTRKASRLSLAASKARRVPCPVSSLVIGVECGGSDTTS 159

Query: 296 GVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNY 355
           G++ NP +G  +D++V  G TV+ SE +E   A HL   RA +  V +  +  +   ++ 
Sbjct: 160 GLSCNPVIGRMADMVVAGGGTVIISETSEFIGAEHLFAERAADGRVREAFVTAVRNMEDL 219

Query: 356 L-NMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAA 414
             + G   R   PSP NK+GGL  V EKALG++AK+G S +V VL  G+ P K+GL +  
Sbjct: 220 AISRGVDMREDQPSPDNKRGGLTTVEEKALGAMAKAGTSPLVGVLRYGEAPQKKGLHFMD 279

Query: 415 TPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGT 474
            PA+     T   A G  +  F TG G P G M  P +K+       +   D +D +   
Sbjct: 280 APAAAVENLTALAAGGCQLTFFGTGVGNPIGSMVAPTVKVCGNVNTLHTMADNIDFDVSG 339

Query: 475 IATGEETIEEVGWKLFHFILDVASGKKKTFS 505
           +    + I ++G +LF + +DVASG + T  
Sbjct: 340 VLQNGDKISDLGEQLFGYAMDVASGTRLTSE 370


>UniRef50_C5EF38 Altronate dehydratase n=2 Tax=Clostridiales RepID=C5EF38_9FIRM
          Length = 405

 Score =  393 bits (1009), Expect = e-107,   Method: Composition-based stats.
 Identities = 109/415 (26%), Positives = 173/415 (41%), Gaps = 39/415 (9%)

Query: 116 EGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNH 175
             ++++GY    G+ G +N + +  +V C   V   +V+         +P+V+ +VG + 
Sbjct: 2   TEWSWQGYGRKHGAPGIRNRVLVIYTVKCSEFVARRIVEE------SGHPDVE-LVGFD- 53

Query: 176 LYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPV 235
               G   N  A  +    + ++  +PN G  V+ +GLGCE +QP+ L            
Sbjct: 54  ----GCTDNQYAVDL----LISLIKHPNVGA-VLTVGLGCEYIQPQWLA------DVAVK 98

Query: 236 ESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFS 295
           E      +  ++  G +  V          L++L    R      +LV+G +CGGSD  S
Sbjct: 99  EGKEASWMSIQQEGGTKPTVTKGTAWVRETLERLKHTPRVRMGFKDLVIGAECGGSDYTS 158

Query: 296 GVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNY 355
           G+  N  VG   D LV  G   +F E+ E      LL  RA + E  +   E    YD  
Sbjct: 159 GLAGNVVVGRFFDRLVDLGGCAIFEEIVEAIGLDGLLVGRAADPEAAR---ELRYTYDKA 215

Query: 356 LNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAA- 414
           L+  ++ R  + SPGN  GGL+ + EK++G++ KSG   I  VL     P   GL     
Sbjct: 216 LDYCRSVRQYSVSPGNFAGGLSTIEEKSMGAVIKSGSRPIEGVLKVSVPPKHGGLWLLDS 275

Query: 415 TPA-----------SDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANR 463
           TP            +D       ++ G  +    TGRG   G    P IK+    E  +R
Sbjct: 276 TPDPHFMQFGITNPNDNEGLMDLISCGAHIVFLVTGRGNVVGSAVAPCIKITGNHETFSR 335

Query: 464 WFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFN 518
             + MD +A  I  G  + +E+   L  ++   A G   T S+  G       + 
Sbjct: 336 MEEDMDFDASPILYGGMSQKEMALDLAAYVAGTAGGTP-TKSEVLGHKEFYIPYK 389


>UniRef50_A7VSH2 Putative uncharacterized protein n=1 Tax=Clostridium leptum DSM 753
           RepID=A7VSH2_9CLOT
          Length = 404

 Score =  385 bits (990), Expect = e-105,   Method: Composition-based stats.
 Identities = 110/409 (26%), Positives = 169/409 (41%), Gaps = 36/409 (8%)

Query: 121 EGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCG 180
           +GY  ADGS G +N + +  +V C   + + + +  +        +V+ V       G  
Sbjct: 8   QGYVRADGSKGIRNKVLVIYTVECCRALSERIARHFQE----LGQDVEAV-------GTS 56

Query: 181 VAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASI 240
             ++  A    IR +   S +PN G  V+ IG GCE  +P+++                 
Sbjct: 57  SCLDNQA---DIRRLLRFSTHPNVGA-VLAIGHGCEYTKPQKIAEF------ARQRGRES 106

Query: 241 VSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTAN 300
                ++  G     +  L+I    L+KL    RE    SELV+  +CGGSD  SG+  N
Sbjct: 107 QWFYQQEAGGSVKGYDKGLEIVRELLKKLEATPREPMYLSELVLAGECGGSDFTSGLAGN 166

Query: 301 PAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGK 360
             +G   D LV  G T +F E+ E       L  RA    V   +      YD  +    
Sbjct: 167 ALIGRVFDRLVDAGGTAIFEELCEGLGLKEYLAARAATPRVADDI---RRAYDKTMEFCV 223

Query: 361 TDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATP---- 416
                + +PGN  GGL  + EK++G++ KSG   I  VL   Q P K GL    T     
Sbjct: 224 KYGHFSIAPGNMDGGLTTIEEKSMGAMVKSGTRPIRGVLKIAQAPKKPGLYLLDTTPDEK 283

Query: 417 -------ASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMD 469
                  A+D       +A G  +    TGRG   G    PVIK+        R  D +D
Sbjct: 284 LEPAHHEAADPSDMLDLIACGAHIVFLVTGRGHVVGTPVSPVIKVTGNPRTYGRMKDDID 343

Query: 470 INAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFN 518
             A    TG+ +++++   L   +  VA G++ T +++ G    +  FN
Sbjct: 344 FCAAPALTGDRSLDDLSDDLLELVSRVAQGER-TNAERLGHREGILYFN 391


>UniRef50_B6WWW3 Putative uncharacterized protein n=2 Tax=Desulfovibrio
           RepID=B6WWW3_9DELT
          Length = 399

 Score =  383 bits (983), Expect = e-104,   Method: Composition-based stats.
 Identities = 102/412 (24%), Positives = 173/412 (41%), Gaps = 27/412 (6%)

Query: 120 FEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGC 179
           F G+   +G VG +N + +      VA +   +   +    L   PN +G          
Sbjct: 3   FWGFVRENGKVGIRNHVLVVGITRNVATLAYMIASSVRGTRLYVGPNENG---------- 52

Query: 180 GVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESAS 239
               +        R I  ++ NPN GG V+++G   +    E   T  + V+ I      
Sbjct: 53  ---RSRDDRETMARVITGLAKNPNVGG-VLLVGNKPDGGYAE--FTYENIVENIMASGKP 106

Query: 240 IVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTA 299
           + +L   +  G  + +   +Q A    +  + ++RE     +L + ++CG SDA SG+  
Sbjct: 107 VETLFISRDGGHAACIGLGIQKARHLAELCSAQRREEVDWGKLCIAVKCGYSDATSGMAG 166

Query: 300 NPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMG 359
           NP +GY  D L   G T +FSE TEV  A  ++  R  +       L  +   +      
Sbjct: 167 NPVIGYVFDRLCDAGGTAIFSETTEVIGAEEIVARRFADAGQRDVFLSCVRKVEEEAKAT 226

Query: 360 KTD-RSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPAS 418
             D RS NP P N + GL  + EK+LG+IAK+G   I++ +  G+ P+  GL Y  +  S
Sbjct: 227 GQDIRSINPIPANIEAGLTTLEEKSLGAIAKAGTKPIMQCVRYGESPSAPGLNYMDSWMS 286

Query: 419 DFVCGTQQVASGITVQVFTTGRGTPYGLMAVPV---------IKMATRTELANRWFDLMD 469
                    ++G  + +F  G G       +PV         +         +     +D
Sbjct: 287 SSALFAGFSSAGAVLNIFQFGGGAMPDKCMMPVADTGVVAPILFATGNPRAYDHGKLEID 346

Query: 470 INAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAP 521
            N+G + + + +IEE G KL   I D+ASG + T  +   +   + ++   P
Sbjct: 347 FNSGVVISEKASIEETGEKLIRHICDIASG-RMTKVETLNVREPVELYLQGP 397


>UniRef50_A8H9C8 D-galactarate dehydratase/Altronate hydrolase domain protein n=3
           Tax=Proteobacteria RepID=A8H9C8_SHEPA
          Length = 393

 Score =  347 bits (890), Expect = 7e-94,   Method: Composition-based stats.
 Identities = 110/393 (27%), Positives = 176/393 (44%), Gaps = 33/393 (8%)

Query: 119 TFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYG 178
           +F G+   DGSVG +N + I     C  G+   +   I+          +G+V  N+   
Sbjct: 4   SFIGFGRTDGSVGIRNHVLIMAVDECCDGIARAIADSID----------NGIVVTNYNT- 52

Query: 179 CGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESA 238
           C    N       I T+ +   NPN  G V+V+ +GC  + PE +         I     
Sbjct: 53  CMYGGNEE----MINTMIHTGNNPNVAG-VLVLAMGCGSIDPEIVAA------PIRETGR 101

Query: 239 SIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVT 298
              SL   K  G ++ +    ++A++  Q      R   P SEL++G++CGGSD  SG+ 
Sbjct: 102 PAFSLVCMKQQGTRATINQGKELAQQLQQAAQDAPRVEKPISELIIGVKCGGSDTSSGIA 161

Query: 299 ANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNM 358
           +NP+VG A D LV  GAT +  E+ E+     +L  RAV+ EV  +L   +  +      
Sbjct: 162 SNPSVGRAVDTLVDMGATAIAGELIELVGCESILRQRAVSTEVADKLERLI--HQEEARW 219

Query: 359 GKTDRS-ANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPG----QRPTKRGLIYA 413
                     S GN  GGL  + EK+ G+++K+G  AI +VL       ++PT  G   +
Sbjct: 220 HVDGAEVETMSIGNSVGGLTTLEEKSFGALSKTGTRAIQDVLQINHLVHEKPTTAGFYLS 279

Query: 414 ATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAG 473
                    G    A G  + ++TTG G  +    VPVI+++    L     + +DI+A 
Sbjct: 280 EATHLCGSAGMHFAALGAHLILWTTG-GAGFNNPIVPVIRVSGNQYL---LNEDIDIDAS 335

Query: 474 TIATGEETIEEVGWKLFHFILDVASGKKKTFSD 506
            I   EE +E V  ++   +  VA G++    +
Sbjct: 336 GIMRAEEGVESVAERIVAKVSKVAQGQQTNIEE 368


>UniRef50_D0Z3R7 Altronate hydrolase n=2 Tax=Bacteria RepID=D0Z3R7_LISDA
          Length = 391

 Score =  336 bits (863), Expect = 9e-91,   Method: Composition-based stats.
 Identities = 113/392 (28%), Positives = 175/392 (44%), Gaps = 32/392 (8%)

Query: 116 EGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNH 175
              TF+G+   +G+ G +N + I     C  G+   + K I+          D VV  NH
Sbjct: 1   MTMTFKGFPRPNGTFGIRNNVMIVAIDECCEGIARNISKEID----------DSVVVTNH 50

Query: 176 LYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPV 235
            Y C    N       I TI + + NPN  G V+VI +GC  + PE +         I  
Sbjct: 51  -YTCMYGGNEE----MIDTIIHTATNPNIAG-VLVIAMGCGSIDPEMVAE------PIRK 98

Query: 236 ESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFS 295
           E   + +L   K+ G    ++D L +A+      +  +R   P S L +G++CGGSD  S
Sbjct: 99  EGLPVHTLTVIKNKGTIETIKDGLVLAKELKAYADSVERIDAPISALRIGIKCGGSDTSS 158

Query: 296 GVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNY 355
           G+ +NP+VG ASD LV  GAT M  E+ E+     +L  R+V  EVG ++   +   ++ 
Sbjct: 159 GLASNPSVGAASDKLVDMGATTMAGELLELLGCEEILKARSVTPEVGSKIERLIA--EDL 216

Query: 356 LNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPG----QRPTKRGLI 411
                 + +   S GN  GGL  + EK+ G++ K+G   I + L       ++PTK G  
Sbjct: 217 KRWHVIEGTETMSIGNSVGGLTTIDEKSQGAMHKTGTQPIQDCLRINHIHREKPTKPGFY 276

Query: 412 YAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDIN 471
              T            + G  + ++T G    +    VPVI+++  + L       MDIN
Sbjct: 277 LTETTMLCGGAAMHFASLGCQLILWTAG-AAGFNNSIVPVIRVSGNSALITA---DMDIN 332

Query: 472 AGTIATGEETIEEVGWKLFHFILDVASGKKKT 503
           A  I    +TI+ V  K+   +  VA G    
Sbjct: 333 ACGIMDATDTIDNVSNKIIDKVFAVADGLPTN 364


>UniRef50_B5JYR2 D-Galactarate dehydratase n=1 Tax=Octadecabacter antarcticus 238
           RepID=B5JYR2_9RHOB
          Length = 359

 Score =  330 bits (847), Expect = 7e-89,   Method: Composition-based stats.
 Identities = 88/367 (23%), Positives = 152/367 (41%), Gaps = 13/367 (3%)

Query: 157 ERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCE 216
           +R        V GV+ L   +  G  +    A +    I+ I  +PN G  ++V   G  
Sbjct: 5   DRVTTLAAEQVPGVLPLTPAFQRG--LRGIDATLQHDMINAIIAHPNVGAALVVTHDGAS 62

Query: 217 KLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRET 276
             Q  R                 IV +      G Q+  E +       L +  ++ +  
Sbjct: 63  ADQLRRFCAEL---------GKPIVIVALMAQQGMQAACETMAAHLRSLLAEAAEQSKSK 113

Query: 277 CPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRA 336
               +L V ++CGGSDA S + ANPA+G   D L+  G T + SE  E      ++  ++
Sbjct: 114 FLLPDLTVALECGGSDATSALCANPAIGRFVDRLIDAGGTAIVSETAEFLGGEDIVLAQS 173

Query: 337 VNEEVGKRLLEEMEWYDNYLNMGKTD-RSANPSPGNKKGGLANVVEKALGSIAKSGKSAI 395
              +V   +L  +   D  +    TD R  NP+  N + GL+ + EK +G++ K G S  
Sbjct: 174 RTPQVADAILAYLSAEDAIMTSDGTDYRGVNPTQENIEAGLSTLTEKTMGALCKIGTSRF 233

Query: 396 VEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMA 455
              L+ G+ PT +GL +  TP       T  V  G  V +F  G   P GL   P IK+ 
Sbjct: 234 AGALNFGEEPTGKGLFFMNTPFFSPTSLTGMVLGGAQVSLFAMGVFNPSGLPLAPTIKIC 293

Query: 456 TRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLA 515
              +  + W D +D++   + +G          +   + D+++G + T ++++     + 
Sbjct: 294 GNPKTLSDWPDAIDLDVSGVISGRMNYGAAADDILRIVRDISNG-QVTCAERFQEGQIIL 352

Query: 516 VFNPAPV 522
               +P+
Sbjct: 353 PITQSPL 359


>UniRef50_D2S1L8 Altronate dehydratase-like protein n=1 Tax=Haloterrigena turkmenica
           DSM 5511 RepID=D2S1L8_9EURY
          Length = 373

 Score =  281 bits (719), Expect = 5e-74,   Method: Composition-based stats.
 Identities = 92/412 (22%), Positives = 148/412 (35%), Gaps = 47/412 (11%)

Query: 112 LPPLEGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVV 171
                   F  Y      VG +N + +  SV C   V D +              V G V
Sbjct: 5   PSSASEIGFTAYDRDRDGVGVRNRVLVVPSVICSHTVADRIASE-----------VPGAV 53

Query: 172 GLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQ 231
              H +GCG   +        RT+  ++ NPN  G  + +GLGCE +Q +RL     D  
Sbjct: 54  STPHDHGCGQLGDDSERT--ERTLVGVAANPNVAG-ALAVGLGCETVQSDRLAGSIADR- 109

Query: 232 AIPVESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGS 291
                   +  +  ++  G  +  E  +  A   L+   +  R         +G+     
Sbjct: 110 -----GVPVEEVAIQRAGGTDACREAGIDRAT-ALRARTEATRSQVGLEAATIGVVSSDC 163

Query: 292 DAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEW 351
              S  TA+P VG     +V  G   + +    V        P AV E V     E  E 
Sbjct: 164 RPSSLETADPLVGSVVGRIVDAGGRALIAGNERVH-----AHPDAVRERVAT--AEARER 216

Query: 352 YDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKS-GKSAIVEVLSPGQRPTK-RG 409
           +D     G TDR+ + SP           +     + +  G  ++ +VL  G+R T   G
Sbjct: 217 FD-----GVTDRAYD-SPAAVTATRKRAADATPEQVRRLWGDRSVRDVLEYGERATHDAG 270

Query: 410 LIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMD 469
           +     P++     T   A+G  + +  T  G P G   VPV+ +    +  +   D +D
Sbjct: 271 VALVDAPSAFDEAATALAAAGAQIVIHVTADGIPAGHPIVPVLAVTGDRDTYDALCDDLD 330

Query: 470 INAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAP 521
             AG         E    +L   +  V  G+  T S++ G+ +  A+    P
Sbjct: 331 TFAG---------ETTPDELLATLRAVLDGEP-TSSERHGVTS-FAITRVGP 371


>UniRef50_C8T5I2 D-galactarate dehydratase n=3 Tax=Enterobacteriaceae
           RepID=C8T5I2_KLEPR
          Length = 172

 Score =  200 bits (508), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 139/166 (83%), Positives = 148/166 (89%)

Query: 1   MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDI 60
           MA+I IRQ++PTAFYIKV  TDNVAIIVND GL AGTRFPDGL L+EHIPQGHKVAL+DI
Sbjct: 1   MADIAIRQQSPTAFYIKVDPTDNVAIIVNDRGLTAGTRFPDGLTLVEHIPQGHKVALVDI 60

Query: 61  PANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTF 120
           PA+GEIIRYGEVIGYAVR IP+GSWIDES+V LP APPL+TLPLATKVPEPLPPLEGYTF
Sbjct: 61  PAHGEIIRYGEVIGYAVRDIPQGSWIDESLVELPTAPPLNTLPLATKVPEPLPPLEGYTF 120

Query: 121 EGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPN 166
           EGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKII        P 
Sbjct: 121 EGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIINATCCQTIPT 166


>UniRef50_B7DPM4 Altronate dehydratase n=1 Tax=Alicyclobacillus acidocaldarius LAA1
           RepID=B7DPM4_9BACL
          Length = 223

 Score =  195 bits (496), Expect = 4e-48,   Method: Composition-based stats.
 Identities = 39/192 (20%), Positives = 73/192 (38%), Gaps = 5/192 (2%)

Query: 12  TAFYIKVHDTDNVAIIVNDNGLKAGTRFPDG-LELIEHIPQGHKVALLDIPANGEIIRYG 70
            +  + +   D+V + +    +      P G +     + +GHK+A   +     + +YG
Sbjct: 2   ASKVLHLSPVDDVVVALEPLDVGEVVETPFGSVSARAPVSRGHKLADRHVQCGEPVRKYG 61

Query: 71  EVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSV 130
             IG A + I  G W+    +         +              +G TF GY  +DG V
Sbjct: 62  FPIGLAGQDIEPGEWVHTHNLRTALMERDDSYVYLPSGSPMPVLDDGLTFLGYVRSDGQV 121

Query: 131 GTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVV 190
           G +N + I  +V CV  V + +  + +     +   +DGV    H YGC    +      
Sbjct: 122 GVRNEIWILNTVGCVNKVAERLAAMADAR--WRGGGIDGVYHFAHPYGCSQLGDDLVYTQ 179

Query: 191 PIRTIHNISLNP 202
            +  +  +  +P
Sbjct: 180 SL--LAGLVRHP 189


>UniRef50_B9TLG0 Putative uncharacterized protein (Fragment) n=1 Tax=Ricinus
           communis RepID=B9TLG0_RICCO
          Length = 217

 Score =  173 bits (439), Expect = 1e-41,   Method: Composition-based stats.
 Identities = 46/218 (21%), Positives = 79/218 (36%), Gaps = 31/218 (14%)

Query: 14  FYIKVHDTDNVAIIVNDNGLKAGTRF-PDGLELIEHIPQGHKVALLDIPANGEIIRYGEV 72
             I +H  D++ + + D        +  + + +   +   HK+A         +  YG V
Sbjct: 3   KVICIHPDDSMLVALTDLAPGDVVTWNGENILVSTPVKTKHKLARRAFAEGDLLTMYGVV 62

Query: 73  IGYAVRAIPRGSWIDESMVVLPEAPPL--HTLPLATKVPEPLPPLEGYTFEGYRNADGSV 130
           +G A + I +G  +    +    +      + P     P+ +  L+  TF+G   ADG V
Sbjct: 63  VGKATQPIRKGEAVTTDNLAHYASEVEIGESKPYTWTPPD-VSDLQDATFDGVVRADGRV 121

Query: 131 GTKNLLGITTSVHCVAGVVDYVVKIIERDLLPK-------------------------YP 165
           GT N   I   V C    V+++   +E  L                            +P
Sbjct: 122 GTANYWLIFPLVFCENRNVEHLRNALEGPLGYATNDLASLTFQLLGEDMEAPKPVVRPFP 181

Query: 166 NVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPN 203
           NVDGV  + H  GCG       A    + +   + +PN
Sbjct: 182 NVDGVRIITHNGGCGGTR--ADARSLCKILAAYADHPN 217


>UniRef50_D2QGM2 Putative uncharacterized protein n=1 Tax=Spirosoma linguale DSM 74
           RepID=D2QGM2_9SPHI
          Length = 343

 Score =  156 bits (394), Expect = 2e-36,   Method: Composition-based stats.
 Identities = 45/279 (16%), Positives = 82/279 (29%), Gaps = 54/279 (19%)

Query: 97  PPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVGTKNLLGITTSV-------------- 142
           P         +        +  +F GY   DG VGT+N   + +                
Sbjct: 7   PSDFPGATHWRAE---SNRQSLSFMGYYRPDGRVGTRNYWLVISLAPVDPEQMALFQEAC 63

Query: 143 ------HCVAGVVDYVVKIIERDLL-----------------PKYPNVDGVVGLNHLYGC 179
                  C       +  + E+                    P + N+DG+  L      
Sbjct: 64  QTVLGYQCPNAYEQQLRNLREQYRAGSYFNTPAPQPVRSVPKPVFTNIDGIRFLPV---- 119

Query: 180 GVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESAS 239
               +A A    +  +     + N GG + V+  G    +   L          P  S  
Sbjct: 120 -YDDSAMALEAVLDVLAGYCTHANVGG-ITVLSGGATTDRVRALHQCIAKRD--PAFSKP 175

Query: 240 IVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTA 299
           ++ +    +      +        R +  LN++ R + P S LV+  Q G ++       
Sbjct: 176 MLVVDRLTYRSDSDWLTAATYDTFRGMALLNKQTRRSAPLSRLVISTQQGKTNES---LP 232

Query: 300 NPAVGYASDLLVRCGATVMFSEV---TEVRDAIHLLTPR 335
           N  V      +   GATV+  +    T++     +   R
Sbjct: 233 NQVVDECVQFMASVGATVLLVDTNQSTDIHGVQLISETR 271


>UniRef50_UPI00017F2C45 Altronate dehydratase n=2 Tax=Enterobacteriaceae
           RepID=UPI00017F2C45
          Length = 119

 Score =  138 bits (348), Expect = 5e-31,   Method: Composition-based stats.
 Identities = 32/119 (26%), Positives = 47/119 (39%), Gaps = 2/119 (1%)

Query: 14  FYIKVHDTDNVAIIVNDNGLKAGTRFP-DGLELIEHIPQGHKVALLDIPANGEIIRYGEV 72
            YIK+H  DNVA+ + D             + L + + +GHK AL +I     +I+YG  
Sbjct: 2   QYIKIHALDNVAVALADLAEGTEVSVDNQTVRLRQDVARGHKFALTNIAKGANVIKYGLP 61

Query: 73  IGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVG 131
           IGYA+  I  G  +            L          +          + YR A+G VG
Sbjct: 62  IGYALADIAAGEHVHAHNTR-TNLSDLDQYRYQPDFHDLPAQAADREVQIYRRANGDVG 119


>UniRef50_UPI00017F3110 galactarate dehydratase n=1 Tax=Escherichia coli O157:H7 str.
          EC4024 RepID=UPI00017F3110
          Length = 114

 Score =  114 bits (286), Expect = 7e-24,   Method: Composition-based stats.
 Identities = 75/82 (91%), Positives = 80/82 (97%)

Query: 1  MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDI 60
          MA+IEIRQ +PTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVAL+DI
Sbjct: 1  MADIEIRQASPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALVDI 60

Query: 61 PANGEIIRYGEVIGYAVRAIPR 82
          PA+GEI+RYGEVIGYAVRAI R
Sbjct: 61 PAHGEIVRYGEVIGYAVRAIRR 82


>UniRef50_A8MAM1 SAF domain protein n=5 Tax=cellular organisms RepID=A8MAM1_CALMQ
          Length = 106

 Score =  113 bits (282), Expect = 2e-23,   Method: Composition-based stats.
 Identities = 28/93 (30%), Positives = 45/93 (48%), Gaps = 5/93 (5%)

Query: 6  IRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDG-----LELIEHIPQGHKVALLDI 60
          ++ E+     I +  +DNVA+ + D    +      G     ++LI++IP GHK AL DI
Sbjct: 1  MKAESTVKEAIVLSPSDNVAVALRDLKSGSLITLDVGSLRLTVKLIDNIPFGHKFALKDI 60

Query: 61 PANGEIIRYGEVIGYAVRAIPRGSWIDESMVVL 93
          P    +++YG  IG A R I  G  +    +  
Sbjct: 61 PKCSLVVKYGHTIGRAKRDIKAGEHVHVHNLES 93


>UniRef50_B4D086 SAF domain protein n=1 Tax=Chthoniobacter flavus Ellin428
           RepID=B4D086_9BACT
          Length = 106

 Score =  109 bits (272), Expect = 4e-22,   Method: Composition-based stats.
 Identities = 24/100 (24%), Positives = 38/100 (38%), Gaps = 1/100 (1%)

Query: 13  AFYIKVHDTDNVAIIVNDNGLKAGTRFPDG-LELIEHIPQGHKVALLDIPANGEIIRYGE 71
              +++H  DNV  ++      A  R  D  + +   +P GHK+A   + A  +I++YG 
Sbjct: 7   PRLLRLHPADNVLTVIATLESGARIRVGDAEVVVPTRLPIGHKIAARALHAGEKIVKYGA 66

Query: 72  VIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEP 111
            IG A R I  G       V     P            + 
Sbjct: 67  PIGSASRDIAAGEHAHTHNVQSDYLPTFLREDQTRFFAQH 106


>UniRef50_D2PG65 SAF domain protein n=15 Tax=cellular organisms RepID=D2PG65_SULIS
          Length = 100

 Score =  105 bits (263), Expect = 4e-21,   Method: Composition-based stats.
 Identities = 22/93 (23%), Positives = 39/93 (41%), Gaps = 8/93 (8%)

Query: 13 AFYIKVHDTDNVAIIVNDNGLKA---GTRFPD-----GLELIEHIPQGHKVALLDIPANG 64
            ++  +  DNV + + D        G    D      ++ I +IP GHK+AL ++    
Sbjct: 2  PHFLIHNKNDNVGVAITDIKAGEEVEGVYIEDMAKGPKIKAINNIPLGHKIALSNLKQGD 61

Query: 65 EIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAP 97
           +I+YG  IG A++ I  G  +    +      
Sbjct: 62 TVIKYGRPIGSAIKEIKIGEHVHVHNIKSNRWG 94


>UniRef50_D2NF82 Truncated altronate dehydratase n=2 Tax=Escherichia coli
           RepID=D2NF82_ECOLX
          Length = 108

 Score =  103 bits (256), Expect = 2e-20,   Method: Composition-based stats.
 Identities = 22/101 (21%), Positives = 39/101 (38%), Gaps = 1/101 (0%)

Query: 13  AFYIKVHDTDNVAIIVNDNGLKAGTRFPDG-LELIEHIPQGHKVALLDIPANGEIIRYGE 71
              +K+H  DN  + +ND        + +G +     +  GHK+A   +     I++YG 
Sbjct: 8   KRALKLHAKDNCVVALNDIASGDIVWWDEGEMVACSSVTLGHKLACEALNNGDSILKYGA 67

Query: 72  VIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPL 112
           +IG+A R I  G  +    +        H      +  E  
Sbjct: 68  IIGHATRDIAMGEHVHSHNLASNAIAIFHHDDAGYQSEEKA 108


>UniRef50_C8ZXV8 D-galactarate dehydratase n=1 Tax=Enterococcus gallinarum EG2
          RepID=C8ZXV8_ENTGA
          Length = 99

 Score =  102 bits (255), Expect = 3e-20,   Method: Composition-based stats.
 Identities = 29/98 (29%), Positives = 47/98 (47%), Gaps = 7/98 (7%)

Query: 1  MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLEL-----IEHIPQGHKV 55
          M+  ++RQ   TA  + +   DNVA+++     ++     +   L     ++ I   HK 
Sbjct: 1  MSEEKVRQSMYTA--LMMRPEDNVAVVLQPTPAESFVNIVNQASLNEFLIVQSIDSYHKF 58

Query: 56 ALLDIPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVL 93
          ++ DI    EII+YGEVIG A  AI +G  +    V  
Sbjct: 59 SVKDIEFGEEIIKYGEVIGIATAAIAKGEHVHTHNVRS 96


>UniRef50_Q5WIZ0 Altronate hydrolase N-terminus n=5 Tax=Bacteria RepID=Q5WIZ0_BACSK
          Length = 96

 Score =  102 bits (254), Expect = 4e-20,   Method: Composition-based stats.
 Identities = 27/94 (28%), Positives = 35/94 (37%), Gaps = 2/94 (2%)

Query: 10  TPTAFYIKVHDTDNVAIIVNDNGLKAGTRF--PDGLELIEHIPQGHKVALLDIPANGEII 67
           + T  ++ +   DNVA  + D              L L  HI  GHK AL  I    +I 
Sbjct: 2   SETKTHVVMQQKDNVATALRDFEKGQVVTLAGEQRLHLKNHIGFGHKFALCPIKKGADIT 61

Query: 68  RYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHT 101
           +YGEVIG A   I  G  +    V          
Sbjct: 62  KYGEVIGVASTDIAAGEHVHLHNVEGKRGRGDQR 95


>UniRef50_A7VSH3 Putative uncharacterized protein n=1 Tax=Clostridium leptum DSM 753
           RepID=A7VSH3_9CLOT
          Length = 136

 Score =  102 bits (254), Expect = 4e-20,   Method: Composition-based stats.
 Identities = 28/85 (32%), Positives = 41/85 (48%), Gaps = 6/85 (7%)

Query: 17  KVHDTDNVAIIVNDNGLKAGTRFPD------GLELIEHIPQGHKVALLDIPANGEIIRYG 70
           +V   DNVA  + D    + +   D       +E ++ IP GHK+AL DI     II+YG
Sbjct: 18  QVSAQDNVATALGDIPAGSVSVTGDIGPQGKNIEALQEIPYGHKIALRDIKPGEFIIKYG 77

Query: 71  EVIGYAVRAIPRGSWIDESMVVLPE 95
             I  A + IP+G+W+    V    
Sbjct: 78  VKIAVATQDIPKGAWVHLHNVRSEY 102


>UniRef50_Q0RXU4 Possible sulfolactate sulfo-lyase small subunit n=1
          Tax=Rhodococcus jostii RHA1 RepID=Q0RXU4_RHOSR
          Length = 102

 Score =  101 bits (253), Expect = 5e-20,   Method: Composition-based stats.
 Identities = 31/99 (31%), Positives = 48/99 (48%), Gaps = 6/99 (6%)

Query: 6  IRQETPTAFYIKVHDTDNVAIIVNDNGLKAGT----RFPDGL--ELIEHIPQGHKVALLD 59
          ++  T    ++  HD D VA+ V D    A      R P+ +  EL++ IP GHKVAL+D
Sbjct: 1  MKNATRAPDFLAHHDGDVVAVAVRDLEPGAAEGGYLRGPESVSLELLDPIPLGHKVALVD 60

Query: 60 IPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPP 98
          + A  ++I YG  +G     I RGS++    +       
Sbjct: 61 LEAGQDVIEYGLRVGVTTEKITRGSYVHVHNIRSARWQN 99


>UniRef50_B8FML5 SAF domain protein n=1 Tax=Desulfatibacillum alkenivorans AK-01
          RepID=B8FML5_DESAA
          Length = 88

 Score =  101 bits (253), Expect = 5e-20,   Method: Composition-based stats.
 Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 2/85 (2%)

Query: 13 AFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIE--HIPQGHKVALLDIPANGEIIRYG 70
             I V+  DNVA+ + D G     R  + +       I   HKV L D+    ++I+YG
Sbjct: 3  PNAIMVNPADNVAVALEDIGQGEEVRVGEKVLCRTIADIAYSHKVLLKDLSEGEDVIKYG 62

Query: 71 EVIGYAVRAIPRGSWIDESMVVLPE 95
          E+IG A + + +G W+    + L  
Sbjct: 63 EIIGQAAQDLKQGEWVHTHNLTLKG 87


>UniRef50_C5EFR7 Predicted protein n=1 Tax=Clostridiales bacterium 1_7_47FAA
          RepID=C5EFR7_9FIRM
          Length = 93

 Score =  101 bits (252), Expect = 6e-20,   Method: Composition-based stats.
 Identities = 27/85 (31%), Positives = 44/85 (51%), Gaps = 3/85 (3%)

Query: 14 FYIKVHDTDNVAIIVND--NGLKAGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRYGE 71
            I+  + DNVA+++ D   GL  G    D + + + IP GHK+AL DI A  ++ +YGE
Sbjct: 7  KIIRFTEKDNVAVVLEDVKPGLVMGLDGAD-ITVGDEIPYGHKIALSDIAAGEKVYKYGE 65

Query: 72 VIGYAVRAIPRGSWIDESMVVLPEA 96
           +   ++ I +G W+    V     
Sbjct: 66 PVARCIKDIKKGEWVHVHNVESIRG 90


>UniRef50_Q6L322 Altronate hydrolase n=1 Tax=Picrophilus torridus
          RepID=Q6L322_PICTO
          Length = 98

 Score =  101 bits (251), Expect = 1e-19,   Method: Composition-based stats.
 Identities = 21/87 (24%), Positives = 39/87 (44%), Gaps = 5/87 (5%)

Query: 15 YIKVHDTDNVAIIVNDNGLKA-----GTRFPDGLELIEHIPQGHKVALLDIPANGEIIRY 69
           + + + DNVA ++  +         G      +   + IP GHK+A+ +I     +I+Y
Sbjct: 7  ALVIDEKDNVATLLEGSKAGEKVQLKGLTCEKSIICNQDIPSGHKIAIKNIKLGESVIKY 66

Query: 70 GEVIGYAVRAIPRGSWIDESMVVLPEA 96
          GE+IG A + I  G ++    +     
Sbjct: 67 GEIIGRATKEIKIGDYVHIHNIDSIRG 93


>UniRef50_Q3ACL1 Hydrolase, UxaA family n=1 Tax=Carboxydothermus hydrogenoformans
          Z-2901 RepID=Q3ACL1_CARHZ
          Length = 97

 Score = 99.6 bits (247), Expect = 3e-19,   Method: Composition-based stats.
 Identities = 22/84 (26%), Positives = 38/84 (45%), Gaps = 5/84 (5%)

Query: 15 YIKVHDTDNVAIIVNDNGLKAGTRFP-----DGLELIEHIPQGHKVALLDIPANGEIIRY 69
           I +++ DNVA ++ D  L     F        +   E+IP  HK+A+ ++     + +Y
Sbjct: 7  AIVINENDNVATVIEDINLGDVVVFEILGKTQEIIARENIPIYHKIAIKEVRVGEYVYKY 66

Query: 70 GEVIGYAVRAIPRGSWIDESMVVL 93
          G+ IG A R I  G  +    +  
Sbjct: 67 GQKIGVATRDIQIGEHVHSHNLSS 90


>UniRef50_B5J029 Putative uncharacterized protein n=1 Tax=Octadecabacter antarcticus
           307 RepID=B5J029_9RHOB
          Length = 122

 Score = 99.2 bits (246), Expect = 4e-19,   Method: Composition-based stats.
 Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 7/117 (5%)

Query: 142 VHCVAGVVDYVVKIIER-DLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISL 200
           ++  A V+      I    LL  Y +VDGVV L H  GCG+A +     +  R +   ++
Sbjct: 1   MNRSATVIRRAASEIAASRLLEDYASVDGVVALAHGTGCGMANSGWGFDILDRVLWGHAI 60

Query: 201 NPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVED 257
           +PN G  V  +GLGCE +Q   + + +              +L  +   G ++ ++ 
Sbjct: 61  HPNVGATV-FVGLGCEVMQIAGMQSHSGTAGTDRFH-----ALTIQDTGGTRATIDA 111


>UniRef50_Q9HIE8 Putative uncharacterized protein Ta1392 n=1 Tax=Thermoplasma
          acidophilum RepID=Q9HIE8_THEAC
          Length = 95

 Score = 98.9 bits (245), Expect = 4e-19,   Method: Composition-based stats.
 Identities = 24/90 (26%), Positives = 36/90 (40%), Gaps = 7/90 (7%)

Query: 14 FYIKVHDTDNVAIIVNDNGLKAGTRFPD-------GLELIEHIPQGHKVALLDIPANGEI 66
            +     D+VA+  +D       +           +   E IP GHK++L DI     +
Sbjct: 6  KALAHAKNDSVAVATDDLKEGEEIQVAFLDNNEKTKITTAEVIPLGHKISLKDIKKGENV 65

Query: 67 IRYGEVIGYAVRAIPRGSWIDESMVVLPEA 96
          I YGEVIG A + I RG  +    +     
Sbjct: 66 IEYGEVIGAATKDIKRGEHVHIHNIKSLRW 95


>UniRef50_A1WPF7 SAF domain n=4 Tax=Burkholderiales RepID=A1WPF7_VEREI
          Length = 113

 Score = 98.9 bits (245), Expect = 4e-19,   Method: Composition-based stats.
 Identities = 24/100 (24%), Positives = 37/100 (37%), Gaps = 4/100 (4%)

Query: 13  AFYIKVHDTDNVAIIVNDNGLKAGT----RFPDGLELIEHIPQGHKVALLDIPANGEIIR 68
              I +H  DNVA +++                 +   + I  GHK+ +  IP    +++
Sbjct: 14  PRGIILHTADNVATLIDPARDGQTCTLQGEVAGQVIARQDIAFGHKICIAPIPLGANVLK 73

Query: 69  YGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKV 108
           YG+VIG A RAI  G       V    A          + 
Sbjct: 74  YGQVIGRATRAIAAGEHAHVHNVDSARARGDRQERQEVRP 113


>UniRef50_D1Y7V9 Mannonate dehydratase n=1 Tax=Pyramidobacter piscolens W5455
           RepID=D1Y7V9_9BACT
          Length = 98

 Score = 98.9 bits (245), Expect = 5e-19,   Method: Composition-based stats.
 Identities = 19/90 (21%), Positives = 32/90 (35%), Gaps = 1/90 (1%)

Query: 15  YIKVHDTDNVAIIVNDNGLKAGTRFPD-GLELIEHIPQGHKVALLDIPANGEIIRYGEVI 73
            I V+  DN+   +          F          IPQ HK+A+ +I       +YGE+I
Sbjct: 4   VIHVNPRDNLVTCLRPVAKGERIEFEGKNYVAAADIPQFHKMAVAEIKKGEHCYKYGEII 63

Query: 74  GYAVRAIPRGSWIDESMVVLPEAPPLHTLP 103
           G A+  +  G ++    +            
Sbjct: 64  GTALTDLHPGDYVHVHNLESTRGRGDRNAE 93


>UniRef50_C1XHK9 Altronate dehydratase n=2 Tax=Meiothermus RepID=C1XHK9_MEIRU
          Length = 118

 Score = 98.9 bits (245), Expect = 5e-19,   Method: Composition-based stats.
 Identities = 23/110 (20%), Positives = 42/110 (38%), Gaps = 7/110 (6%)

Query: 7   RQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFP-------DGLELIEHIPQGHKVALLD 59
           +++      +    TD+VA+ V D                   ++L+E IP GHK+AL D
Sbjct: 5   KEDLVAYRALAHKSTDDVAVAVADLKAGEELVIHSLEGGQTHRVKLLEDIPLGHKIALRD 64

Query: 60  IPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVP 109
           +P    +I YGE +G   + + +G ++    +                  
Sbjct: 65  MPEGHVVIEYGEKVGRMTQPVKKGGYVHVHNIRTLRWDYGSKSKSQKARA 114


>UniRef50_B8IQB2 SAF domain protein n=8 Tax=Proteobacteria RepID=B8IQB2_METNO
          Length = 105

 Score = 98.5 bits (244), Expect = 5e-19,   Method: Composition-based stats.
 Identities = 25/92 (27%), Positives = 37/92 (40%), Gaps = 8/92 (8%)

Query: 13  AFYIKVHDTDNVAIIV-NDNGLKA---GTRFPDG----LELIEHIPQGHKVALLDIPANG 64
              +     DNVA+ V  D        G    D     +E+   IP GHKVAL D+    
Sbjct: 14  PHLLAHSPLDNVAVAVVEDLKAGTAAFGVVTQDNSTFEVEVRHDIPIGHKVALADLKTGD 73

Query: 65  EIIRYGEVIGYAVRAIPRGSWIDESMVVLPEA 96
             I+YG+ IG  ++ + +G  +    V     
Sbjct: 74  TAIKYGQDIGRVIKDVAKGEHVHVHNVKTKRW 105


>UniRef50_C0GPG6 SAF domain protein n=1 Tax=Desulfonatronospira thiodismutans ASO3-1
           RepID=C0GPG6_9DELT
          Length = 99

 Score = 98.1 bits (243), Expect = 7e-19,   Method: Composition-based stats.
 Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 5/94 (5%)

Query: 13  AFYIKVHDTDNVAIIVNDNGLKAGTRFPD-----GLELIEHIPQGHKVALLDIPANGEII 67
           +  + ++  DNVA    D  +       D      +++ E +  GHK AL DI   G+II
Sbjct: 3   SSAVLINKDDNVATATKDLDVGEKVLVQDDDSTFEIQVKEPVTFGHKFALSDISQGGQII 62

Query: 68  RYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHT 101
           +YGEVIG A R I R   +    V          
Sbjct: 63  KYGEVIGVATRDISRFGHVHVHNVDSIRGTFTDR 96


>UniRef50_B8FVM2 SAF domain protein n=4 Tax=Desulfitobacterium hafniense
          RepID=B8FVM2_DESHD
          Length = 98

 Score = 97.7 bits (242), Expect = 9e-19,   Method: Composition-based stats.
 Identities = 20/95 (21%), Positives = 33/95 (34%), Gaps = 7/95 (7%)

Query: 10 TPTAFYIKVHDTDNVAIIVNDNGLKA---GTRFPDG----LELIEHIPQGHKVALLDIPA 62
            +  ++     D+V + V D        G     G    +     I  GHK+AL     
Sbjct: 1  MSSHKFLLHEAQDDVGVAVQDIKAGEKVMGVDIHSGEEFHVTANHDIQLGHKIALKSKKQ 60

Query: 63 NGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAP 97
             +I+YGE +G   + I  G W+    +      
Sbjct: 61 GENLIKYGENVGKVTQDIKVGDWVHTHNLKTARWD 95


>UniRef50_B1B868 Altronate hydrolase n=7 Tax=cellular organisms RepID=B1B868_CLOBO
          Length = 99

 Score = 97.7 bits (242), Expect = 9e-19,   Method: Composition-based stats.
 Identities = 28/92 (30%), Positives = 38/92 (41%), Gaps = 5/92 (5%)

Query: 13 AFYIKVHDTDNVAIIVNDNGLKAGTRFP-----DGLELIEHIPQGHKVALLDIPANGEII 67
           F +  ++ DNVA  V                   + L   IP GHK AL  I  N EII
Sbjct: 3  KFAVVTNEKDNVATTVKYLRKGEEVVVDVFGDEQKILLNNDIPFGHKFALKSINENEEII 62

Query: 68 RYGEVIGYAVRAIPRGSWIDESMVVLPEAPPL 99
          +YGE IG A + I +G ++    V+       
Sbjct: 63 KYGEEIGQATKNIKQGDYVHVHNVISERGRGD 94


>UniRef50_B8G2E2 SAF domain protein n=2 Tax=Desulfitobacterium hafniense
          RepID=B8G2E2_DESHD
          Length = 103

 Score = 97.7 bits (242), Expect = 1e-18,   Method: Composition-based stats.
 Identities = 24/92 (26%), Positives = 39/92 (42%), Gaps = 5/92 (5%)

Query: 13 AFYIKVHDTDNVAIIVNDNGLKAGTRF-----PDGLELIEHIPQGHKVALLDIPANGEII 67
             + +++ DNVA  V+         F      + L + + IP GHKVAL+ I  +  ++
Sbjct: 3  KQAVVIYEKDNVATCVDHIPAGTTISFFRGSQAESLTVCQDIPLGHKVALIPIAQSSHVV 62

Query: 68 RYGEVIGYAVRAIPRGSWIDESMVVLPEAPPL 99
          +YGE IG A   I  G  +    +        
Sbjct: 63 KYGESIGAATIDIQPGQHVHVHNMESQRGRGD 94


>UniRef50_C9XPT3 Altronate hydrolase (N-terminus) n=4 Tax=Clostridium difficile
           RepID=C9XPT3_CLODC
          Length = 91

 Score = 97.3 bits (241), Expect = 1e-18,   Method: Composition-based stats.
 Identities = 18/88 (20%), Positives = 32/88 (36%), Gaps = 1/88 (1%)

Query: 15  YIKVHDTDNVAIIVNDNGLKAGTRFPD-GLELIEHIPQGHKVALLDIPANGEIIRYGEVI 73
            I  ++ DN+   V                 + ++IP  HK+A  D+     + +YGE+I
Sbjct: 4   IIHANEKDNLVTCVRPLVKGEKVSIDGKSYIVNDNIPVFHKMATEDVKKGDVVYKYGEII 63

Query: 74  GYAVRAIPRGSWIDESMVVLPEAPPLHT 101
           G A   I  G ++    +          
Sbjct: 64  GIATVDIKTGDYVHVHNIESTRGRGDKK 91


>UniRef50_Q184J3 Probable carbohydrate hydrolase (N-terminus) n=5 Tax=Bacteria
           RepID=Q184J3_CLOD6
          Length = 101

 Score = 97.3 bits (241), Expect = 1e-18,   Method: Composition-based stats.
 Identities = 19/93 (20%), Positives = 36/93 (38%), Gaps = 6/93 (6%)

Query: 15  YIKVHDTDNVAIIVNDNGLKAGTRFP------DGLELIEHIPQGHKVALLDIPANGEIIR 68
            + + + DNVA+ +      +   F         +  ++ I   HK+A+ D+    ++ +
Sbjct: 4   AVIIDEKDNVAVAIEAIAKGSEISFKLKDKTVKTITALDDITIYHKLAIKDMAKGDKVTK 63

Query: 69  YGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHT 101
           YGE IG A + I  G  +    V          
Sbjct: 64  YGEHIGEANQEIKSGQHVHIHNVRSVREDLDKQ 96


>UniRef50_B3PBS2 Hydrolase, UxaA family n=2 Tax=Proteobacteria RepID=B3PBS2_CELJU
          Length = 115

 Score = 96.9 bits (240), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 24/88 (27%), Positives = 34/88 (38%), Gaps = 1/88 (1%)

Query: 12  TAFYIKVHDTDNVAIIVNDNGLKAGTRFPDG-LELIEHIPQGHKVALLDIPANGEIIRYG 70
            A  I +H TDNV I V+              L     I  GHKVA L +    +++RYG
Sbjct: 15  VASLILLHPTDNVLICVSPIHAGDAIVIDGTTLVAPMAISVGHKVARLSMSPGDKVLRYG 74

Query: 71  EVIGYAVRAIPRGSWIDESMVVLPEAPP 98
             IG     + +G  +    +     P 
Sbjct: 75  APIGSITEPVNQGEHVHMHNMKSDYIPS 102


>UniRef50_B4TB53 Hydrolase, UxaA family n=14 Tax=Bacteria RepID=B4TB53_SALHS
          Length = 96

 Score = 96.5 bits (239), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 23/92 (25%), Positives = 37/92 (40%), Gaps = 5/92 (5%)

Query: 13 AFYIKVHDTDNVAIIVNDNGLKAGTRF-----PDGLELIEHIPQGHKVALLDIPANGEII 67
             + +H  D VA  +                   + L + +P GHK A+ D+P +GE+ 
Sbjct: 3  KNAVVIHPQDCVATAITALKAGETATMFVGEREISVVLHQDVPFGHKFAICDVPFHGEVY 62

Query: 68 RYGEVIGYAVRAIPRGSWIDESMVVLPEAPPL 99
          +YGE IG A + I  G ++    V        
Sbjct: 63 KYGESIGRATQEIKSGDYVHVHNVESERGRGD 94


>UniRef50_C0D6Q5 Putative uncharacterized protein n=1 Tax=Clostridium
          asparagiforme DSM 15981 RepID=C0D6Q5_9CLOT
          Length = 112

 Score = 96.5 bits (239), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 25/89 (28%), Positives = 40/89 (44%), Gaps = 7/89 (7%)

Query: 14 FYIKVHDTDNVAIIVNDNGLKAGTRFPD-------GLELIEHIPQGHKVALLDIPANGEI 66
           ++++H+ D VA  +   G     R  +        ++  E IP G+K+AL  I     +
Sbjct: 3  RFMRMHEQDMVATALEYTGRGESARVYNPQNELLFEVKAEEDIPFGNKIALTRISKGERV 62

Query: 67 IRYGEVIGYAVRAIPRGSWIDESMVVLPE 95
          I+YG  IG AVR I +G  +    V    
Sbjct: 63 IKYGAPIGVAVRDIQKGRMVHVHNVRSAA 91


>UniRef50_C5SG41 SAF domain protein n=1 Tax=Asticcacaulis excentricus CB 48
          RepID=C5SG41_9CAUL
          Length = 102

 Score = 96.2 bits (238), Expect = 3e-18,   Method: Composition-based stats.
 Identities = 23/90 (25%), Positives = 39/90 (43%), Gaps = 1/90 (1%)

Query: 10 TPTAFYIKVHDTDNVAIIVNDNGLKAGTRFP-DGLELIEHIPQGHKVALLDIPANGEIIR 68
          +  +  I +H +DNVA+        +      + L + E I  GHKVA+ D+ A  +I +
Sbjct: 2  SLPSPLILLHPSDNVAVCRAAITAGSVVTVGAEALLITEPIEVGHKVAVRDLNAGDKIFK 61

Query: 69 YGEVIGYAVRAIPRGSWIDESMVVLPEAPP 98
          YG  IG   +  P+G  +    +       
Sbjct: 62 YGAPIGSMTKDTPKGGHVHMHNMKSDYISS 91


>UniRef50_B6BQ17 D-galactarate dehydratase/Altronate n=2 Tax=root
          RepID=B6BQ17_9RICK
          Length = 94

 Score = 96.2 bits (238), Expect = 3e-18,   Method: Composition-based stats.
 Identities = 21/93 (22%), Positives = 38/93 (40%), Gaps = 8/93 (8%)

Query: 12 TAFYIKVHDTDNVAIIVNDNGLKAGT--------RFPDGLELIEHIPQGHKVALLDIPAN 63
              I     DNV ++V +                    ++ ++ IP GHK+A+ D+   
Sbjct: 2  ATDIIIHDKKDNVGVVVIEKITPKQDCACWIMEDDSSTNIQSLDEIPLGHKIAMTDLNEG 61

Query: 64 GEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEA 96
            I++YG  IG  V++I +G  +    V   + 
Sbjct: 62 DTILKYGHDIGKVVKSIKKGEHVHVHNVKTKKW 94


>UniRef50_D1Y192 Mannonate dehydratase n=1 Tax=Pyramidobacter piscolens W5455
          RepID=D1Y192_9BACT
          Length = 89

 Score = 95.8 bits (237), Expect = 3e-18,   Method: Composition-based stats.
 Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 1/84 (1%)

Query: 14 FYIKVHDTDNVAIIVNDNGLKAGTRFPDG-LELIEHIPQGHKVALLDIPANGEIIRYGEV 72
            +++   DNV  ++ D+        PDG L L++ +   HKV + D+ A   +I+YGE 
Sbjct: 4  RSLQISPADNVKTVLEDSFRGDTIDTPDGPLTLLDDVEFAHKVLIKDLHAGDPVIKYGEE 63

Query: 73 IGYAVRAIPRGSWIDESMVVLPEA 96
          IG      PRG+WI    +     
Sbjct: 64 IGRVKADTPRGTWIHTHNMSCERG 87


>UniRef50_C3WAI6 Carbohydrate hydrolase n=2 Tax=Bacteria RepID=C3WAI6_FUSMR
          Length = 93

 Score = 95.4 bits (236), Expect = 5e-18,   Method: Composition-based stats.
 Identities = 21/88 (23%), Positives = 34/88 (38%), Gaps = 5/88 (5%)

Query: 15 YIKVHDTDNVAIIVNDNGLKAGTRF-----PDGLELIEHIPQGHKVALLDIPANGEIIRY 69
           + +   DNVA+ +          +        LE +  +   HK+A  DI     +++Y
Sbjct: 5  AVVIDKKDNVAVAIETVKKGEVVAYKLDNETVSLEALTDVQIYHKLASKDIKKGEPVVKY 64

Query: 70 GEVIGYAVRAIPRGSWIDESMVVLPEAP 97
          GE IG A R I +G  +    V      
Sbjct: 65 GEHIGIAGRDIQKGEHVHVHNVESHREE 92


>UniRef50_D2RM01 SAF domain protein n=3 Tax=Bacteria RepID=D2RM01_ACIFE
          Length = 100

 Score = 93.9 bits (232), Expect = 1e-17,   Method: Composition-based stats.
 Identities = 24/81 (29%), Positives = 42/81 (51%), Gaps = 5/81 (6%)

Query: 16 IKVHDTDNVAIIVNDNGLKAGTRF-----PDGLELIEHIPQGHKVALLDIPANGEIIRYG 70
          + + D DNV   V +        +      + +E +E+IP  HK+AL D+P   E+I+YG
Sbjct: 6  LLMDDRDNVVTCVAEIHKGEQVVYKKDGREEQVEALENIPFCHKIALTDLPEGSEVIKYG 65

Query: 71 EVIGYAVRAIPRGSWIDESMV 91
          E++G     + RG W+ +  +
Sbjct: 66 ELLGKTNAPVARGHWVSDKNI 86


>UniRef50_C5EF39 Altronate hydrolase n=3 Tax=Clostridiales RepID=C5EF39_9FIRM
          Length = 112

 Score = 93.5 bits (231), Expect = 2e-17,   Method: Composition-based stats.
 Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 5/101 (4%)

Query: 17  KVHDTDNVAIIVNDNGLKA-----GTRFPDGLELIEHIPQGHKVALLDIPANGEIIRYGE 71
           ++   DNVA  +            G    + ++    IP GHK+AL DI A G I++YG 
Sbjct: 9   QIDLGDNVATALAGIKAGQEAGLTGDHGEESIKAATDIPAGHKIALKDIGAGGHIVKYGV 68

Query: 72  VIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPL 112
           VIG A   IP+GSW+   ++          L + T  P+  
Sbjct: 69  VIGRATADIPKGSWVHLHVMQSIYDERSSHLDVRTGAPKDT 109


>UniRef50_A1HS78 Hydrolase, UxaA family n=2 Tax=Thermosinus carboxydivorans Nor1
           RepID=A1HS78_9FIRM
          Length = 103

 Score = 92.7 bits (229), Expect = 3e-17,   Method: Composition-based stats.
 Identities = 27/100 (27%), Positives = 37/100 (37%), Gaps = 5/100 (5%)

Query: 13  AFYIKVHDTDNVAIIVNDNGLKAGTRFPD-----GLELIEHIPQGHKVALLDIPANGEII 67
           A  I +   DNV  +V                   +   E IP GHK+AL +IPA   II
Sbjct: 2   ARAIIMKAIDNVCTVVETVEPPTEVTAEIDGKTITVLATERIPFGHKIALQNIPAGQPII 61

Query: 68  RYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATK 107
           +YGE IG A + I  G  +    +               +
Sbjct: 62  KYGETIGLATQDIQSGQHVHVHNLESCRGRGDKVAIATRQ 101


>UniRef50_B5JYR1 Altronate hydrolase n=1 Tax=Octadecabacter antarcticus 238
          RepID=B5JYR1_9RHOB
          Length = 88

 Score = 92.3 bits (228), Expect = 4e-17,   Method: Composition-based stats.
 Identities = 27/77 (35%), Positives = 39/77 (50%), Gaps = 2/77 (2%)

Query: 16 IKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRYGEVIGY 75
          +K    DNVA +++D      T    G+ + + IP GHKVAL  I A   +I+YG VIG+
Sbjct: 14 LKTQAGDNVATLLDDQL--DCTLISGGMSVDQGIPFGHKVALAPIAAGETVIKYGVVIGH 71

Query: 76 AVRAIPRGSWIDESMVV 92
          A   I  G  +    + 
Sbjct: 72 AKTGIREGEHVHVHNIE 88


>UniRef50_B2T9V7 SAF domain protein n=33 Tax=Burkholderia RepID=B2T9V7_BURPP
          Length = 110

 Score = 91.2 bits (225), Expect = 8e-17,   Method: Composition-based stats.
 Identities = 22/98 (22%), Positives = 36/98 (36%), Gaps = 1/98 (1%)

Query: 13  AFYIKVHDTDNVAIIVNDNGLKAGTRFP-DGLELIEHIPQGHKVALLDIPANGEIIRYGE 71
              I +   DN  I               + + L   I  GHKVA  ++  + +++RYG 
Sbjct: 12  PRLILLSPADNCLIAAARLDCGTQVEIEGERVTLTRTIDLGHKVARHELAKDDKVLRYGA 71

Query: 72  VIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVP 109
           VIG+   A+ RG+ +    +     P          V 
Sbjct: 72  VIGHVTEAVARGAHLHTHNLESDYLPTYTHDAGHEFVH 109


>UniRef50_C2DK38 Putative uncharacterized protein n=2 Tax=Escherichia
           RepID=C2DK38_ECOLX
          Length = 65

 Score = 90.4 bits (223), Expect = 1e-16,   Method: Composition-based stats.
 Identities = 58/65 (89%), Positives = 61/65 (93%)

Query: 286 MQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRL 345
           M CGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVT+V DAIHLLTPRA+NEEVG+ L
Sbjct: 1   MHCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTDVHDAIHLLTPRAINEEVGRCL 60

Query: 346 LEEME 350
           LEEM 
Sbjct: 61  LEEMA 65


>UniRef50_D2S1L9 SAF domain protein n=1 Tax=Haloterrigena turkmenica DSM 5511
           RepID=D2S1L9_9EURY
          Length = 106

 Score = 88.8 bits (219), Expect = 4e-16,   Method: Composition-based stats.
 Identities = 26/97 (26%), Positives = 38/97 (39%), Gaps = 6/97 (6%)

Query: 15  YIKVHDTDNVAIIVNDNGLKAGTRFPD------GLELIEHIPQGHKVALLDIPANGEIIR 68
            + + ++D VA  + D          D       LE+ E I  GHK+A++ I A   + +
Sbjct: 10  AVLLAESDTVATAIADLEAGRSIETDDLPGDRSALEVAEPIAFGHKLAVMAIDAGEPVRK 69

Query: 69  YGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLA 105
           YGEVIG A   I  G W+                  A
Sbjct: 70  YGEVIGTATERIEPGEWVHIHNCESNRGRGDLAEGSA 106


>UniRef50_Q1ASX0 Altronate hydrolase n=1 Tax=Rubrobacter xylanophilus DSM 9941
           RepID=Q1ASX0_RUBXD
          Length = 107

 Score = 88.1 bits (217), Expect = 8e-16,   Method: Composition-based stats.
 Identities = 26/106 (24%), Positives = 41/106 (38%), Gaps = 13/106 (12%)

Query: 4   IEIRQETPTAFYIKVHD------TDNVAIIVNDNGLKA---GTRFPDG----LELIEHIP 50
           I+IR+  P +    +H        D+V +  +D        G    DG    +   E +P
Sbjct: 2   IQIRKILPISRRAGLHKFLIHRRGDHVGVATSDIARGERVVGVYMDDGSAVEVVAREEVP 61

Query: 51  QGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEA 96
            GHK+A+      GE+I YG  IG A      G ++    +     
Sbjct: 62  LGHKIAVERCEPGGEVIEYGVRIGLAPEGFEAGDYVHTHNLKSARW 107


>UniRef50_Q2G5K6 D-galactarate dehydratase/Altronate hydrolase-like protein n=1
          Tax=Novosphingobium aromaticivorans DSM 12444
          RepID=Q2G5K6_NOVAD
          Length = 109

 Score = 87.7 bits (216), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 14/84 (16%), Positives = 29/84 (34%), Gaps = 1/84 (1%)

Query: 15 YIKVHDTDNVAIIVNDNGLKAGTRFPD-GLELIEHIPQGHKVALLDIPANGEIIRYGEVI 73
          ++ +   DN+ +   D             + L + +  GHK+A   + A  +++RYG  I
Sbjct: 13 FLLLDPADNILVCTRDALAGDLVTIDGIHVRLPQPVGVGHKIARRPLAAGEKVLRYGAPI 72

Query: 74 GYAVRAIPRGSWIDESMVVLPEAP 97
          G           +    +      
Sbjct: 73 GSMTADAAIAEHVHSHNLGSDYIA 96


>UniRef50_A4GAA3 Altronate dehydratase (N part) n=3 Tax=Proteobacteria
          RepID=A4GAA3_HERAR
          Length = 93

 Score = 87.7 bits (216), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 22/92 (23%), Positives = 36/92 (39%), Gaps = 10/92 (10%)

Query: 14 FYIKVHDTDNVAIIVNDNGLKAGTRFPD---------GLELIEHIPQGHKVALLDIPANG 64
            +     D VA+ V + G+KAGT              ++ ++ IP GHK+A+  +    
Sbjct: 3  HVVLHDAKDTVAVAVVE-GIKAGTDLTAWIMDDDRTVSIKALQDIPMGHKIAMKPMAVGD 61

Query: 65 EIIRYGEVIGYAVRAIPRGSWIDESMVVLPEA 96
           + +YG  IG  V A   G       +     
Sbjct: 62 TVFKYGVDIGKVVAAAKAGEHAHVHNIKTKRW 93


>UniRef50_C0CW84 Putative uncharacterized protein n=1 Tax=Clostridium
          asparagiforme DSM 15981 RepID=C0CW84_9CLOT
          Length = 96

 Score = 87.3 bits (215), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 7/92 (7%)

Query: 15 YIKVHDTDNVAII-VNDNGLKAGTRFPDG------LELIEHIPQGHKVALLDIPANGEII 67
           +KV D DNVA +        A     D       +  ++ IP GHKVA+  I    +I+
Sbjct: 4  ALKVSDLDNVATVFAEGIQAGAEIEVRDKKGESVVIRALDPIPYGHKVAVRGIETGEQIM 63

Query: 68 RYGEVIGYAVRAIPRGSWIDESMVVLPEAPPL 99
          +YGE IG A RAI  G+ +    +        
Sbjct: 64 KYGEEIGVASRAIAAGNHVHVHNLDSMRGRGD 95


>UniRef50_C0CYJ4 Putative uncharacterized protein n=1 Tax=Clostridium
          asparagiforme DSM 15981 RepID=C0CYJ4_9CLOT
          Length = 101

 Score = 87.3 bits (215), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 5/84 (5%)

Query: 15 YIKVHDTDNVAIIVNDNGLKAGTRFPDG-----LELIEHIPQGHKVALLDIPANGEIIRY 69
           + + +TDNV   V +        +  G     +E +E IP  HK+AL+      E+++Y
Sbjct: 8  ALMMEETDNVVTCVMEIKKGDAVVYRKGDTYCTVEALEDIPYCHKIALIPFDEGDEVVKY 67

Query: 70 GEVIGYAVRAIPRGSWIDESMVVL 93
          GE+IG   RAI +G  ++   +  
Sbjct: 68 GEMIGRTNRAIGKGCLVNHENIYS 91


>UniRef50_B0PEC9 Putative uncharacterized protein n=1 Tax=Anaerotruncus
          colihominis DSM 17241 RepID=B0PEC9_9FIRM
          Length = 103

 Score = 87.3 bits (215), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 9/88 (10%)

Query: 13 AFYIKVHDTDNVAIIVNDNGLKAGTRFP-------DGLELIEHIPQGHKVALLDIPANGE 65
          A  I +   DNV  +V  +G K G           + L   E IP  HK A+  I   G 
Sbjct: 3  ANAILLSTKDNVVTVV--DGAKQGEEIRYFANGELESLIARETIPPCHKAAIAPIEPGGH 60

Query: 66 IIRYGEVIGYAVRAIPRGSWIDESMVVL 93
          +++YGE IG A R I  G W+    +  
Sbjct: 61 VLKYGESIGAATRPIGVGEWVSHLNIES 88


>UniRef50_B0K1I8 SAF domain n=9 Tax=Thermoanaerobacterales RepID=B0K1I8_THEPX
          Length = 96

 Score = 86.1 bits (212), Expect = 3e-15,   Method: Composition-based stats.
 Identities = 19/92 (20%), Positives = 38/92 (41%), Gaps = 6/92 (6%)

Query: 11 PTAFYIKVHDTDNVAIIVNDNGLKAGTRFP------DGLELIEHIPQGHKVALLDIPANG 64
               I ++  D+VA  ++                 + L  ++ I   HK+A++ I +  
Sbjct: 3  SIKKAILLNKADSVATALSQIQKGDVVDIIYNNETVNRLIALDDIEIYHKIAVVPIQSGN 62

Query: 65 EIIRYGEVIGYAVRAIPRGSWIDESMVVLPEA 96
           + +YGEVIG A+++I  G  +    +     
Sbjct: 63 NVYKYGEVIGKAIKSIEIGQCVHIDNIESVRG 94


>UniRef50_B0T1B9 D-galactarate dehydratase/altronate hydrolase-like protein n=1
          Tax=Caulobacter sp. K31 RepID=B0T1B9_CAUSK
          Length = 98

 Score = 86.1 bits (212), Expect = 3e-15,   Method: Composition-based stats.
 Identities = 15/85 (17%), Positives = 31/85 (36%), Gaps = 1/85 (1%)

Query: 15 YIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIE-HIPQGHKVALLDIPANGEIIRYGEVI 73
           I +H  DNV ++                 + +  +  GHK+A  D+    ++++YG  I
Sbjct: 3  LILLHPDDNVLVLSAPVRAGQVLTIDGRTAVADADVGTGHKLARHDLAIGDKVLKYGAPI 62

Query: 74 GYAVRAIPRGSWIDESMVVLPEAPP 98
          G    ++  G  +    +       
Sbjct: 63 GSITASVAAGGHVHLHNMKSDYIAS 87


>UniRef50_B9MJB7 SMP-30/Gluconolaconase/LRE domain protein n=1 Tax=Diaphorobacter
          sp. TPSY RepID=B9MJB7_DIAST
          Length = 197

 Score = 84.6 bits (208), Expect = 8e-15,   Method: Composition-based stats.
 Identities = 36/66 (54%), Positives = 44/66 (66%)

Query: 18 VHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRYGEVIGYAV 77
          +H  DNVAI+ ND GL AGTR   G  L++ +PQ HKVAL DIP  G + RY  VIGYA+
Sbjct: 1  MHPADNVAIVANDGGLPAGTRLAGGQVLVDKVPQAHKVALEDIPEGGAVRRYNVVIGYAL 60

Query: 78 RAIPRG 83
          + I  G
Sbjct: 61 KFIAAG 66


>UniRef50_B8IYJ4 SAF domain protein n=5 Tax=Proteobacteria RepID=B8IYJ4_DESDA
          Length = 94

 Score = 83.1 bits (204), Expect = 3e-14,   Method: Composition-based stats.
 Identities = 19/54 (35%), Positives = 25/54 (46%)

Query: 43 LELIEHIPQGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEA 96
           E +  IP GHK+AL D+     II+Y   IG  V+ I RG  +    V     
Sbjct: 41 FETLSDIPIGHKIALKDLAVGDTIIKYSTDIGKVVKPIKRGEHLHVHNVKTKRW 94


>UniRef50_D1U489 SAF domain protein n=1 Tax=Desulfovibrio aespoeensis Aspo-2
          RepID=D1U489_9DELT
          Length = 99

 Score = 82.3 bits (202), Expect = 4e-14,   Method: Composition-based stats.
 Identities = 26/90 (28%), Positives = 37/90 (41%), Gaps = 5/90 (5%)

Query: 15 YIKVHDTDNVAIIVNDNGLKAGTRFP-----DGLELIEHIPQGHKVALLDIPANGEIIRY 69
           I +   DNV   + D        +           ++ IP G K A+ DIPA+G+II+Y
Sbjct: 4  LIVMSAEDNVGNAIEDIVGGDEVSYTVGGKVHTFTAVDEIPFGFKAAVKDIPASGDIIKY 63

Query: 70 GEVIGYAVRAIPRGSWIDESMVVLPEAPPL 99
           EV+G A R I  G  +    V        
Sbjct: 64 KEVVGQAGRDIRAGECVHIHNVEGKRGRGD 93


>UniRef50_B8DQ83 D-galactarate dehydratase/altronate hydrolase-like protein n=5
          Tax=Proteobacteria RepID=B8DQ83_DESVM
          Length = 94

 Score = 81.1 bits (199), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 16/55 (29%), Positives = 26/55 (47%)

Query: 42 GLELIEHIPQGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEA 96
            +++  IP GHK+AL D+     +++YG  IG  V  I +G  +    V     
Sbjct: 40 TFKVLNDIPIGHKLALNDLSVGDTVMKYGTDIGKVVAPIKQGEHLHVHNVKTKRW 94


>UniRef50_Q1QWP1 D-galactarate dehydratase/Altronate hydrolase-like protein n=6
          Tax=Proteobacteria RepID=Q1QWP1_CHRSD
          Length = 94

 Score = 80.8 bits (198), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 16/54 (29%), Positives = 28/54 (51%)

Query: 43 LELIEHIPQGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEA 96
           E+ + IP GHK+A+ D+  +  +I+Y   IG  V++I +G  +    V     
Sbjct: 41 FEVKDAIPIGHKLAIRDLAEDETVIKYSVDIGRVVQSIRQGEHVHVHNVKTKRW 94


>UniRef50_A8H9C9 D-galactarate dehydratase n=4 Tax=Proteobacteria
          RepID=A8H9C9_SHEPA
          Length = 111

 Score = 80.8 bits (198), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 25/92 (27%), Positives = 37/92 (40%), Gaps = 7/92 (7%)

Query: 13 AFYIKVHDTDNVAIIVNDNGLKAGTR-------FPDGLELIEHIPQGHKVALLDIPANGE 65
             I++   DNVA ++ D                 D +  ++ I  G+KVAL DI A   
Sbjct: 2  KKAIQLDPADNVATLLVDAVKGDEIEIISTNNQVIDLVTCLQAITFGNKVALTDIAAQQL 61

Query: 66 IIRYGEVIGYAVRAIPRGSWIDESMVVLPEAP 97
          I +    +G A++AIPRG       V      
Sbjct: 62 ITKASYPVGVAIKAIPRGELAHVQNVRSQRLD 93


>UniRef50_Q58Y44 Sulfolactate sulfo-lyase small subunit n=1 Tax=Paracoccus
          pantotrophus RepID=Q58Y44_PARPN
          Length = 67

 Score = 80.4 bits (197), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 17/57 (29%), Positives = 21/57 (36%)

Query: 40 PDGLELIEHIPQGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEA 96
             L     IP GHKVAL  + A   +I+Y E IG  V     G  +          
Sbjct: 11 DFRLTAKADIPIGHKVALKALKAGDTVIKYHEDIGKMVGDAEVGGHVHTHNCKTKRW 67


>UniRef50_Q0RXW3 Putative uncharacterized protein n=1 Tax=Rhodococcus jostii RHA1
           RepID=Q0RXW3_RHOSR
          Length = 333

 Score = 75.4 bits (184), Expect = 5e-12,   Method: Composition-based stats.
 Identities = 22/123 (17%), Positives = 40/123 (32%), Gaps = 22/123 (17%)

Query: 6   IRQETPTAFYIKVHDTDNVAIIVNDNGLKAG------TRFPDGLELIEHIPQGHKVALLD 59
           +  ++P    +   D D VA+   D            +   + ++L + +P GHK+AL D
Sbjct: 179 MSNQSP--DLLAHSDGDAVAVGARDLSTGPVPVEDLESTQTEHVDLADAVPLGHKLALRD 236

Query: 60  IPANGEIIRYGEVIGYAVRAIPR---GSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLE 116
           +     +I YG  +G A    P    G+            P         +         
Sbjct: 237 VAEGEPVIDYGLAVGAATTDTPAWRQGTH-----------PQGQEFSAGKQARPERQSPT 285

Query: 117 GYT 119
             +
Sbjct: 286 RRS 288


>UniRef50_B5J028 Putative uncharacterized protein n=1 Tax=Octadecabacter antarcticus
           307 RepID=B5J028_9RHOB
          Length = 61

 Score = 58.8 bits (141), Expect = 5e-07,   Method: Composition-based stats.
 Identities = 14/60 (23%), Positives = 23/60 (38%), Gaps = 1/60 (1%)

Query: 67  IRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPE-PLPPLEGYTFEGYRN 125
           I++G+ IG A  AI  G  +     V       + +       +  +P  +  TF GY  
Sbjct: 2   IKFGQFIGQATVAIAAGDHVHTHNCVFANPEKDYAIGADLAAAQRAIPHTDLLTFSGYAR 61


>UniRef50_Q4HS65 Putative uncharacterized protein n=1 Tax=Campylobacter upsaliensis
           RM3195 RepID=Q4HS65_CAMUP
          Length = 61

 Score = 46.1 bits (108), Expect = 0.003,   Method: Composition-based stats.
 Identities = 14/30 (46%), Positives = 17/30 (56%)

Query: 425 QQVASGITVQVFTTGRGTPYGLMAVPVIKM 454
             VA G  + VFTTGRG   G + V  IK+
Sbjct: 29  AMVAGGANICVFTTGRGMLTGSVIVLTIKI 58


  Database: uniref50.fasta
    Posted date:  Mar 8, 2010 10:38 AM
  Number of letters in database: 1,040,396,356
  Number of sequences in database:  3,077,464
  
Lambda     K      H
   0.310    0.146    0.415 

Lambda     K      H
   0.267   0.0449    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,289,280,554
Number of Sequences: 3077464
Number of extensions: 152384142
Number of successful extensions: 378632
Number of sequences better than 1.0e-01: 117
Number of HSP's better than  0.1 without gapping: 305
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 377341
Number of HSP's gapped (non-prelim): 353
length of query: 523
length of database: 1,040,396,356
effective HSP length: 133
effective length of query: 390
effective length of database: 631,093,644
effective search space: 246126521160
effective search space used: 246126521160
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.1 bits)
S2: 96 (41.5 bits)
