Phyre 2 Results for P08142

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Email | l.a.kelley@imperial.ac.uk
Description | P08142
Date | Thu Jan 5 11:00:40 GMT 2012
Unique Job ID | 536f460d5c62b698

Summary |

Top model
Image coloured by rainbow N → C terminus
| Close Jmol

Model (left) based on template c1yi1A_
Top template information
PDB header:transferase Chain: A: PDB Molecule:acetolactate synthase; PDBTitle: crystal structure of arabidopsis thaliana acetohydroxyacid synthase in2 complex with a sulfonylurea herbicide, tribenuron methyl
Confidence and coverage
Confidence: | 100.0% | Coverage: | 99%
556 residues ( 99% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | A | S | S | G | T | T | S | T | R | K | R | F | T | G | A | E | F | I | V | H | F | L | E | Q | Q | G | I | K | I | V | T | G | I | P | G | G | S | I | L | P | V | Y | D | A | L | S | Q | S | T | Q | I | R | H | I | L | A | R | H | E
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | Q | G | A | G | F | I | A | Q | G | M | A | R | T | D | G | K | P | A | V | C | M | A | C | S | G | P | G | A | T | N | L | V | T | A | I | A | D | A | R | L | D | S | I | P | L | I | C | I | T | G | Q | V | P | A | S | M | I | G | T | D
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  | ? |  | ? |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | A | F | Q | E | V | D | T | Y | G | I | S | I | P | I | T | K | H | N | Y | L | V | R | H | I | E | E | L | P | Q | V | M | S | D | A | F | R | I | A | Q | S | G | R | P | G | P | V | W | I | D | I | P | K | D | V | Q | T | A | V | F | E
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240
Sequence |  | I | E | T | Q | P | A | M | A | E | K | A | A | A | P | A | F | S | E | E | S | I | R | D | A | A | A | M | I | N | A | A | K | R | P | V | L | Y | L | G | G | G | V | I | N | A | P | A | R | V | R | E | L | A | E | K | A | Q | L | P | T
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  | ? |  |  | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300
Sequence |  | T | M | T | L | M | A | L | G | M | L | P | K | A | H | P | L | S | L | G | M | L | G | M | H | G | V | R | S | T | N | Y | I | L | Q | E | A | D | L | L | I | V | L | G | A | R | F | D | D | R | A | I | G | K | T | E | Q | F | C | P | N
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360
Sequence |  | A | K | I | I | H | V | D | I | D | R | A | E | L | G | K | I | K | Q | P | H | V | A | I | Q | A | D | V | D | D | V | L | A | Q | L | I | P | L | V | E | A | Q | P | R | A | E | W | H | Q | L | V | A | D | L | Q | R | E | F | P | C | P
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420
Sequence |  | I | P | K | A | C | D | P | L | S | H | Y | G | L | I | N | A | V | A | A | C | V | D | D | N | A | I | I | T | T | D | V | G | Q | H | Q | M | W | T | A | Q | A | Y | P | L | N | R | P | R | Q | W | L | T | S | G | G | L | G | T | M | G
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480
Sequence |  | F | G | L | P | A | A | I | G | A | A | L | A | N | P | D | R | K | V | L | C | F | S | G | D | G | S | L | M | M | N | I | Q | E | M | A | T | A | S | E | N | Q | L | D | V | K | I | I | L | M | N | N | E | A | L | G | L | V | H | Q | Q
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540
Sequence |  | Q | S | L | F | Y | E | Q | G | V | F | A | A | T | Y | P | G | K | I | N | F | M | Q | I | A | A | G | F | G | L | E | T | C | D | L | N | N | E | A | D | P | Q | A | S | L | Q | E | I | I | N | R | P | G | P | A | L | I | H | V | R | I
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  | ? | ? |  |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | .
Sequence |  | D | A | E | E | K | V | Y | P | M | V | P | P | G | A | A | N | T | E | M | V | G | E
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| c1yi1A_ |

### PDB 1yi1 chain A

Region: 6 - 562
Aligned: 556
Modelled: 557
Confidence: 100.0%
Identity: 43%
PDB header:transferase
Chain: A: PDB Molecule:acetolactate synthase;
PDBTitle: crystal structure of arabidopsis thaliana acetohydroxyacid synthase in2 complex with a sulfonylurea herbicide, tribenuron methyl

Phyre2
2 |
| c1powA_ |

### PDB 1pow chain A

Region: 11 - 551
Aligned: 537
Modelled: 541
Confidence: 100.0%
Identity: 27%
PDB header:oxidoreductase(oxygen as acceptor)
Chain: A: PDB Molecule:pyruvate oxidase;
PDBTitle: the refined structures of a stabilized mutant and of wild-type2 pyruvate oxidase from lactobacillus plantarum

Phyre2
3 |
| c1t9dB_ |

### PDB 1t9d chain B

Region: 12 - 562
Aligned: 539
Modelled: 551
Confidence: 100.0%
Identity: 42%
PDB header:transferase
Chain: B: PDB Molecule:acetolactate synthase, mitochondrial;
PDBTitle: crystal structure of yeast acetohydroxyacid synthase in2 complex with a sulfonylurea herbicide, metsulfuron methyl

Phyre2
4 |
| c2djiA_ |

### PDB 2dji chain A

Region: 12 - 552
Aligned: 536
Modelled: 541
Confidence: 100.0%
Identity: 25%
PDB header:oxidoreductase
Chain: A: PDB Molecule:pyruvate oxidase;
PDBTitle: crystal structure of pyruvate oxidase from aerococcus2 viridans containing fad

Phyre2
5 |
| c2panF_ |

### PDB 2pan chain F

Region: 12 - 561
Aligned: 546
Modelled: 534
Confidence: 100.0%
Identity: 30%
PDB header:lyase
Chain: F: PDB Molecule:glyoxylate carboligase;
PDBTitle: crystal structure of e. coli glyoxylate carboligase

Phyre2
6 |
| c2pgnA_ |

### PDB 2pgn chain A

Region: 14 - 560
Aligned: 544
Modelled: 546
Confidence: 100.0%
Identity: 27%
PDB header:hydrolase
Chain: A: PDB Molecule:cyclohexane-1,2-dione hydrolase (cdh);
PDBTitle: the crystal structure of fad and thdp-dependent cyclohexane-1,2-dione2 hydrolase in complex with cyclohexane-1,2-dione

Phyre2
7 |
| c3eyaE_ |

### PDB 3eya chain E

Region: 12 - 549
Aligned: 516
Modelled: 522
Confidence: 100.0%
Identity: 28%
PDB header:oxidoreductase
Chain: E: PDB Molecule:pyruvate dehydrogenase [cytochrome];
PDBTitle: structural basis for membrane binding and catalytic2 activation of the peripheral membrane enzyme pyruvate3 oxidase from escherichia coli

Phyre2
8 |
| c1jscA_ |

### PDB 1jsc chain A

Region: 4 - 543
Aligned: 523
Modelled: 523
Confidence: 100.0%
Identity: 41%
PDB header:lyase
Chain: A: PDB Molecule:acetohydroxy-acid synthase;
PDBTitle: crystal structure of the catalytic subunit of yeast2 acetohydroxyacid synthase: a target for herbicidal3 inhibitors

Phyre2
9 |
| c1ozhD_ |

### PDB 1ozh chain D

Region: 10 - 549
Aligned: 528
Modelled: 540
Confidence: 100.0%
Identity: 29%
PDB header:lyase
Chain: D: PDB Molecule:acetolactate synthase, catabolic;
PDBTitle: the crystal structure of klebsiella pneumoniae acetolactate2 synthase with enzyme-bound cofactor and with an unusual3 intermediate.

Phyre2
10 |
| c2ag1A_ |

### PDB 2ag1 chain A

Region: 12 - 548
Aligned: 535
Modelled: 536
Confidence: 100.0%
Identity: 26%
PDB header:lyase
Chain: A: PDB Molecule:benzaldehyde lyase;
PDBTitle: crystal structure of benzaldehyde lyase (bal)- semet

Phyre2
11 |
| c2q27B_ |

### PDB 2q27 chain B

Region: 11 - 546
Aligned: 526
Modelled: 536
Confidence: 100.0%
Identity: 24%
PDB header:lyase
Chain: B: PDB Molecule:oxalyl-coa decarboxylase;
PDBTitle: crystal structure of oxalyl-coa decarboxylase from escherichia coli

Phyre2
12 |
| c2v3wC_ |

### PDB 2v3w chain C

Region: 14 - 542
Aligned: 517
Modelled: 529
Confidence: 100.0%
Identity: 27%
PDB header:lyase
Chain: C: PDB Molecule:benzoylformate decarboxylase;
PDBTitle: crystal structure of the benzoylformate decarboxylase2 variant l461a from pseudomonas putida

Phyre2
13 |
| c1zpdA_ |

### PDB 1zpd chain A

Region: 12 - 562
Aligned: 537
Modelled: 550
Confidence: 100.0%
Identity: 20%
PDB header:alcohol fermentation
Chain: A: PDB Molecule:pyruvate decarboxylase;
PDBTitle: pyruvate decarboxylase from zymomonas mobilis

Phyre2
14 |
| c2ji6B_ |

### PDB 2ji6 chain B

Region: 12 - 559
Aligned: 531
Modelled: 548
Confidence: 100.0%
Identity: 25%
PDB header:lyase
Chain: B: PDB Molecule:oxalyl-coa decarboxylase;
PDBTitle: x-ray structure of oxalyl-coa decarboxylase in complex with2 3-deaza-thdp and oxalyl-coa

Phyre2
15 |
| c2x7jA_ |

### PDB 2x7j chain A

Region: 14 - 544
Aligned: 530
Modelled: 531
Confidence: 100.0%
Identity: 17%
PDB header:transferase
Chain: A: PDB Molecule:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene
PDBTitle: structure of the menaquinone biosynthesis protein mend from2 bacillus subtilis

Phyre2
16 |
| c2vbiF_ |

### PDB 2vbi chain F

Region: 12 - 558
Aligned: 529
Modelled: 539
Confidence: 100.0%
Identity: 20%
PDB header:lyase
Chain: F: PDB Molecule:pyruvate decarboxylase;
PDBTitle: holostructure of pyruvate decarboxylase from acetobacter2 pasteurianus

Phyre2
17 |
| c1upaC_ |

### PDB 1upa chain C

Region: 14 - 543
Aligned: 528
Modelled: 530
Confidence: 100.0%
Identity: 25%
PDB header:synthase
Chain: C: PDB Molecule:carboxyethylarginine synthase;
PDBTitle: carboxyethylarginine synthase from streptomyces2 clavuligerus (semet structure)

Phyre2
18 |
| c2vbgB_ |

### PDB 2vbg chain B

Region: 7 - 559
Aligned: 521
Modelled: 547
Confidence: 100.0%
Identity: 20%
PDB header:lyase
Chain: B: PDB Molecule:branched-chain alpha-ketoacid decarboxylase;
PDBTitle: the complex structure of the branched-chain keto acid2 decarboxylase (kdca) from lactococcus lactis with 2r-1-3 hydroxyethyl-deazathdp

Phyre2
19 |
| c2jlaD_ |

### PDB 2jla chain D

Region: 14 - 562
Aligned: 534
Modelled: 544
Confidence: 100.0%
Identity: 17%
PDB header:transferase
Chain: D: PDB Molecule:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene
PDBTitle: crystal structure of e.coli mend, 2-succinyl-5-enolpyruvyl-2 6-hydroxy-3-cyclohexadiene-1-carboxylate synthase - semet3 protein

Phyre2
20 |
| c1ovmC_ |

### PDB 1ovm chain C

Region: 13 - 550
Aligned: 505
Modelled: 505
Confidence: 100.0%
Identity: 19%
PDB header:lyase
Chain: C: PDB Molecule:indole-3-pyruvate decarboxylase;
PDBTitle: crystal structure of indolepyruvate decarboxylase from2 enterobacter cloacae

Phyre2
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Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | c1yi1A_ |
|  | 100.0 | 43 | PDB header:transferase Chain: A: PDB Molecule:acetolactate synthase; PDBTitle: crystal structure of arabidopsis thaliana acetohydroxyacid synthase in2 complex with a sulfonylurea herbicide, tribenuron methyl
2 | c1powA_ |
|  | 100.0 | 27 | PDB header:oxidoreductase(oxygen as acceptor) Chain: A: PDB Molecule:pyruvate oxidase; PDBTitle: the refined structures of a stabilized mutant and of wild-type2 pyruvate oxidase from lactobacillus plantarum
3 | c1t9dB_ |
|  | 100.0 | 42 | PDB header:transferase Chain: B: PDB Molecule:acetolactate synthase, mitochondrial; PDBTitle: crystal structure of yeast acetohydroxyacid synthase in2 complex with a sulfonylurea herbicide, metsulfuron methyl
4 | c2djiA_ |
|  | 100.0 | 25 | PDB header:oxidoreductase Chain: A: PDB Molecule:pyruvate oxidase; PDBTitle: crystal structure of pyruvate oxidase from aerococcus2 viridans containing fad
5 | c2panF_ |
|  | 100.0 | 30 | PDB header:lyase Chain: F: PDB Molecule:glyoxylate carboligase; PDBTitle: crystal structure of e. coli glyoxylate carboligase
6 | c2pgnA_ |
|  | 100.0 | 27 | PDB header:hydrolase Chain: A: PDB Molecule:cyclohexane-1,2-dione hydrolase (cdh); PDBTitle: the crystal structure of fad and thdp-dependent cyclohexane-1,2-dione2 hydrolase in complex with cyclohexane-1,2-dione
7 | c3eyaE_ |
|  | 100.0 | 28 | PDB header:oxidoreductase Chain: E: PDB Molecule:pyruvate dehydrogenase [cytochrome]; PDBTitle: structural basis for membrane binding and catalytic2 activation of the peripheral membrane enzyme pyruvate3 oxidase from escherichia coli
8 | c1jscA_ |
|  | 100.0 | 41 | PDB header:lyase Chain: A: PDB Molecule:acetohydroxy-acid synthase; PDBTitle: crystal structure of the catalytic subunit of yeast2 acetohydroxyacid synthase: a target for herbicidal3 inhibitors
9 | c1ozhD_ |
|  | 100.0 | 29 | PDB header:lyase Chain: D: PDB Molecule:acetolactate synthase, catabolic; PDBTitle: the crystal structure of klebsiella pneumoniae acetolactate2 synthase with enzyme-bound cofactor and with an unusual3 intermediate.
10 | c2ag1A_ |
|  | 100.0 | 26 | PDB header:lyase Chain: A: PDB Molecule:benzaldehyde lyase; PDBTitle: crystal structure of benzaldehyde lyase (bal)- semet
11 | c2q27B_ |
|  | 100.0 | 24 | PDB header:lyase Chain: B: PDB Molecule:oxalyl-coa decarboxylase; PDBTitle: crystal structure of oxalyl-coa decarboxylase from escherichia coli
12 | c2v3wC_ |
|  | 100.0 | 27 | PDB header:lyase Chain: C: PDB Molecule:benzoylformate decarboxylase; PDBTitle: crystal structure of the benzoylformate decarboxylase2 variant l461a from pseudomonas putida
13 | c1zpdA_ |
|  | 100.0 | 20 | PDB header:alcohol fermentation Chain: A: PDB Molecule:pyruvate decarboxylase; PDBTitle: pyruvate decarboxylase from zymomonas mobilis
14 | c2ji6B_ |
|  | 100.0 | 25 | PDB header:lyase Chain: B: PDB Molecule:oxalyl-coa decarboxylase; PDBTitle: x-ray structure of oxalyl-coa decarboxylase in complex with2 3-deaza-thdp and oxalyl-coa
15 | c2x7jA_ |
|  | 100.0 | 17 | PDB header:transferase Chain: A: PDB Molecule:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene PDBTitle: structure of the menaquinone biosynthesis protein mend from2 bacillus subtilis
16 | c2vbiF_ |
|  | 100.0 | 20 | PDB header:lyase Chain: F: PDB Molecule:pyruvate decarboxylase; PDBTitle: holostructure of pyruvate decarboxylase from acetobacter2 pasteurianus
17 | c1upaC_ |
|  | 100.0 | 25 | PDB header:synthase Chain: C: PDB Molecule:carboxyethylarginine synthase; PDBTitle: carboxyethylarginine synthase from streptomyces2 clavuligerus (semet structure)
18 | c2vbgB_ |
|  | 100.0 | 20 | PDB header:lyase Chain: B: PDB Molecule:branched-chain alpha-ketoacid decarboxylase; PDBTitle: the complex structure of the branched-chain keto acid2 decarboxylase (kdca) from lactococcus lactis with 2r-1-3 hydroxyethyl-deazathdp
19 | c2jlaD_ |
|  | 100.0 | 17 | PDB header:transferase Chain: D: PDB Molecule:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene PDBTitle: crystal structure of e.coli mend, 2-succinyl-5-enolpyruvyl-2 6-hydroxy-3-cyclohexadiene-1-carboxylate synthase - semet3 protein
20 | c1ovmC_ |
|  | 100.0 | 19 | PDB header:lyase Chain: C: PDB Molecule:indole-3-pyruvate decarboxylase; PDBTitle: crystal structure of indolepyruvate decarboxylase from2 enterobacter cloacae
21 | c2nxwB_ |
| not modelled | 100.0 | 24 | PDB header:lyase Chain: B: PDB Molecule:phenyl-3-pyruvate decarboxylase; PDBTitle: crystal structure of phenylpyruvate decarboxylase of azospirillum2 brasilense
22 | c2w93A_ |
| not modelled | 100.0 | 18 | PDB header:lyase Chain: A: PDB Molecule:pyruvate decarboxylase isozyme 1; PDBTitle: crystal structure of the saccharomyces cerevisiae pyruvate2 decarboxylase variant e477q in complex with the surrogate3 pyruvamide
23 | c3lq1A_ |
| not modelled | 100.0 | 17 | PDB header:transferase Chain: A: PDB Molecule:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene- PDBTitle: crystal structure of 2-succinyl-6-hydroxy-2,4-cyclohexadiene2 1-carboxylic acid synthase/2-oxoglutarate decarboxylase3 from listeria monocytogenes str. 4b f2365
24 | d1ybha3 |
| not modelled | 100.0 | 43 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module
25 | d1ybha2 |
| not modelled | 100.0 | 49 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase Pyr module
26 | d1t9ba3 |
| not modelled | 100.0 | 38 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module
27 | d2djia2 |
| not modelled | 100.0 | 25 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase Pyr module
28 | d1ozha2 |
| not modelled | 100.0 | 38 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase Pyr module
29 | d2ji7a2 |
| not modelled | 100.0 | 28 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase Pyr module
30 | d1q6za2 |
| not modelled | 100.0 | 30 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase Pyr module
31 | d1t9ba2 |
| not modelled | 100.0 | 51 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase Pyr module
32 | d2ez9a3 |
| not modelled | 100.0 | 27 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module
33 | d2ihta2 |
| not modelled | 100.0 | 29 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase Pyr module
34 | d1zpda2 |
| not modelled | 100.0 | 20 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase Pyr module
35 | d2djia3 |
| not modelled | 100.0 | 20 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module
36 | d1pvda2 |
| not modelled | 100.0 | 18 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase Pyr module
37 | d1ozha3 |
| not modelled | 100.0 | 26 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module
38 | d2ez9a2 |
| not modelled | 100.0 | 31 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase Pyr module
39 | d2ihta3 |
| not modelled | 100.0 | 23 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module
40 | d1zpda3 |
| not modelled | 100.0 | 21 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module
41 | d1ovma2 |
| not modelled | 100.0 | 21 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase Pyr module
42 | d1q6za3 |
| not modelled | 100.0 | 26 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module
43 | d1ovma3 |
| not modelled | 100.0 | 20 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module
44 | d2ji7a3 |
| not modelled | 100.0 | 23 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module
45 | d1pvda3 |
| not modelled | 100.0 | 19 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module
46 | d1jsca3 |
| not modelled | 100.0 | 37 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module
47 | d2ez9a1 |
| not modelled | 100.0 | 22 | Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain
48 | d2djia1 |
| not modelled | 100.0 | 26 | Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain
49 | d1ybha1 |
| not modelled | 100.0 | 37 | Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain
50 | d1t9ba1 |
| not modelled | 100.0 | 39 | Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain
51 | d2ihta1 |
| not modelled | 100.0 | 22 | Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain
52 | d1ozha1 |
| not modelled | 100.0 | 22 | Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain
53 | d2ji7a1 |
| not modelled | 100.0 | 25 | Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain
54 | d1zpda1 |
| not modelled | 99.9 | 16 | Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain
55 | d1ovma1 |
| not modelled | 99.9 | 17 | Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain
56 | d1q6za1 |
| not modelled | 99.9 | 25 | Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain
57 | d1pvda1 |
| not modelled | 99.9 | 22 | Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain
58 | c2c3yA_ |
| not modelled | 99.9 | 10 | PDB header:oxidoreductase Chain: A: PDB Molecule:pyruvate-ferredoxin oxidoreductase; PDBTitle: crystal structure of the radical form of2 pyruvate:ferredoxin oxidoreductase from desulfovibrio3 africanus
59 | d2c42a1 |
| not modelled | 99.8 | 9 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:PFOR Pyr module
60 | c3cf4G_ |
| not modelled | 99.6 | 18 | PDB header:oxidoreductase Chain: G: PDB Molecule:acetyl-coa decarboxylase/synthase epsilon subunit; PDBTitle: structure of the codh component of the m. barkeri acds complex
61 | d2c42a2 |
| not modelled | 99.6 | 19 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:PFOR PP module
62 | c1yd7A_ |
| not modelled | 99.6 | 18 | PDB header:oxidoreductase Chain: A: PDB Molecule:2-keto acid:ferredoxin oxidoreductase subunit PDBTitle: conserved hypothetical protein pfu-1647980-001 from2 pyrococcus furiosus
63 | d2r8oa2 |
| not modelled | 99.6 | 19 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:TK-like PP module
64 | d1r9ja2 |
| not modelled | 99.5 | 23 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:TK-like PP module
65 | d1gpua1 |
| not modelled | 99.5 | 24 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:TK-like PP module
66 | d1w85a_ |
| not modelled | 99.5 | 19 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Branched-chain alpha-keto acid dehydrogenase PP module
67 | d1itza1 |
| not modelled | 99.5 | 27 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:TK-like PP module
68 | d2ozla1 |
| not modelled | 99.5 | 23 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Branched-chain alpha-keto acid dehydrogenase PP module
69 | d2bfda1 |
| not modelled | 99.5 | 18 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Branched-chain alpha-keto acid dehydrogenase PP module
70 | d1umda_ |
| not modelled | 99.5 | 19 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Branched-chain alpha-keto acid dehydrogenase PP module
71 | c3m7iA_ |
| not modelled | 99.4 | 23 | PDB header:transferase Chain: A: PDB Molecule:transketolase; PDBTitle: crystal structure of transketolase in complex with thiamine2 diphosphate, ribose-5-phosphate(pyranose form) and3 magnesium ion
72 | c2o1sC_ |
| not modelled | 99.3 | 25 | PDB header:transferase Chain: C: PDB Molecule:1-deoxy-d-xylulose-5-phosphate synthase; PDBTitle: 1-deoxy-d-xylulose 5-phosphate synthase (dxs) from2 escherichia coli
73 | c2e6kB_ |
| not modelled | 99.3 | 22 | PDB header:transferase Chain: B: PDB Molecule:transketolase; PDBTitle: x-ray structure of thermus thermopilus hb8 tt0505
74 | c2o1xA_ |
| not modelled | 99.3 | 23 | PDB header:transferase Chain: A: PDB Molecule:1-deoxy-d-xylulose-5-phosphate synthase; PDBTitle: 1-deoxy-d-xylulose 5-phosphate synthase (dxs) from2 deinococcus radiodurans
75 | c3hylB_ |
| not modelled | 99.3 | 22 | PDB header:transferase Chain: B: PDB Molecule:transketolase; PDBTitle: crystal structure of transketolase from bacillus anthracis
76 | c3uk1A_ |
| not modelled | 99.3 | 24 | PDB header:transferase Chain: A: PDB Molecule:transketolase; PDBTitle: crystal structure of a transketolase from burkholderia thailandensis2 with an oxidized cysteinesulfonic acid in the active site
77 | c1r9jB_ |
| not modelled | 99.3 | 22 | PDB header:transferase Chain: B: PDB Molecule:transketolase; PDBTitle: transketolase from leishmania mexicana
78 | c1itzC_ |
| not modelled | 99.3 | 27 | PDB header:transferase Chain: C: PDB Molecule:transketolase; PDBTitle: maize transketolase in complex with tpp
79 | c3mosA_ |
| not modelled | 99.3 | 19 | PDB header:transferase Chain: A: PDB Molecule:transketolase; PDBTitle: the structure of human transketolase
80 | c1tkcA_ |
| not modelled | 99.3 | 23 | PDB header:transferase Chain: A: PDB Molecule:transketolase; PDBTitle: specificity of coenzyme binding in thiamin diphosphate2 dependent enzymes: crystal structures of yeast3 transketolase in complex with analogs of thiamin4 diphosphate
81 | c2r8pA_ |
| not modelled | 99.2 | 21 | PDB header:transferase Chain: A: PDB Molecule:transketolase 1; PDBTitle: transketolase from e. coli in complex with substrate d-2 fructose-6-phosphate
82 | c3komB_ |
| not modelled | 99.2 | 21 | PDB header:transferase Chain: B: PDB Molecule:transketolase; PDBTitle: crystal structure of apo transketolase from francisella tularensis
83 | c2g28A_ |
| not modelled | 99.2 | 20 | PDB header:oxidoreductase Chain: A: PDB Molecule:pyruvate dehydrogenase e1 component; PDBTitle: e. coli pyruvate dehydrogenase h407a variant2 phosphonolactylthiamin diphosphate complex
84 | d2ieaa2 |
| not modelled | 99.1 | 23 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:TK-like PP module
85 | d1qs0a_ |
| not modelled | 99.1 | 20 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Branched-chain alpha-keto acid dehydrogenase PP module
86 | c3ahhA_ |
| not modelled | 98.9 | 20 | PDB header:lyase Chain: A: PDB Molecule:xylulose 5-phosphate/fructose 6-phosphate phosphoketolase; PDBTitle: h142a mutant of phosphoketolase from bifidobacterium breve complexed2 with acetyl thiamine diphosphate
87 | c2jgdA_ |
| not modelled | 98.1 | 18 | PDB header:oxidoreductase Chain: A: PDB Molecule:2-oxoglutarate dehydrogenase e1 component; PDBTitle: e. coli 2-oxoglutarate dehydrogenase (e1o)
88 | c1olsB_ |
| not modelled | 98.0 | 12 | PDB header:oxidoreductase Chain: B: PDB Molecule:2-oxoisovalerate dehydrogenase beta subunit; PDBTitle: roles of his291-alpha and his146-beta' in the reductive2 acylation reaction catalyzed by human branched-chain3 alpha-ketoacid dehydrogenase
89 | d1gpua2 |
| not modelled | 98.0 | 13 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:TK-like Pyr module
90 | c2bp7F_ |
| not modelled | 97.9 | 12 | PDB header:oxidoreductase Chain: F: PDB Molecule:2-oxoisovalerate dehydrogenase beta subunit; PDBTitle: new crystal form of the pseudomonas putida branched-chain2 dehydrogenase (e1)
91 | c1efpC_ |
| not modelled | 97.8 | 17 | PDB header:electron transport Chain: C: PDB Molecule:protein (electron transfer flavoprotein); PDBTitle: electron transfer flavoprotein (etf) from paracoccus2 denitrificans
92 | d1r9ja1 |
| not modelled | 97.8 | 15 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:TK-like Pyr module
93 | d2r8oa1 |
| not modelled | 97.8 | 12 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:TK-like Pyr module
94 | d1itza2 |
| not modelled | 97.7 | 15 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:TK-like Pyr module
95 | c1ni4D_ |
| not modelled | 97.6 | 10 | PDB header:oxidoreductase Chain: D: PDB Molecule:pyruvate dehydrogenase e1 component: beta PDBTitle: human pyruvate dehydrogenase
96 | d1ytla1 |
| not modelled | 97.6 | 25 | Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:ACDE2-like
97 | d1qs0b1 |
| not modelled | 97.5 | 17 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Branched-chain alpha-keto acid dehydrogenase Pyr module
98 | c2yicC_ |
| not modelled | 97.5 | 12 | PDB header:lyase Chain: C: PDB Molecule:2-oxoglutarate decarboxylase; PDBTitle: crystal structure of the suca domain of mycobacterium smegmatis2 alpha-ketoglutarate decarboxylase (triclinic form)
99 | d1efva2 |
| not modelled | 97.4 | 15 | Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:C-terminal domain of the electron transfer flavoprotein alpha subunit
100 | c1um9D_ |
| not modelled | 97.3 | 16 | PDB header:oxidoreductase Chain: D: PDB Molecule:2-oxo acid dehydrogenase beta subunit; PDBTitle: branched-chain 2-oxo acid dehydrogenase (e1) from thermus2 thermophilus hb8 in apo-form
101 | d1efpa2 |
| not modelled | 97.3 | 17 | Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:C-terminal domain of the electron transfer flavoprotein alpha subunit
102 | d1w85b1 |
| not modelled | 97.2 | 15 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Branched-chain alpha-keto acid dehydrogenase Pyr module
103 | d2bfdb1 |
| not modelled | 97.2 | 13 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Branched-chain alpha-keto acid dehydrogenase Pyr module
104 | d3clsd2 |
| not modelled | 97.1 | 18 | Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:C-terminal domain of the electron transfer flavoprotein alpha subunit
105 | d2ozlb1 |
| not modelled | 97.1 | 16 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Branched-chain alpha-keto acid dehydrogenase Pyr module
106 | c3dufD_ |
| not modelled | 97.0 | 13 | PDB header:oxidoreductase/transferase Chain: D: PDB Molecule:pyruvate dehydrogenase e1 component subunit beta; PDBTitle: snapshots of catalysis in the e1 subunit of the pyruvate2 dehydrogenase multi-enzyme complex
107 | c3glsC_ |
| not modelled | 96.8 | 14 | PDB header:hydrolase Chain: C: PDB Molecule:nad-dependent deacetylase sirtuin-3, PDBTitle: crystal structure of human sirt3
108 | c2hjhB_ |
| not modelled | 96.6 | 17 | PDB header:hydrolase Chain: B: PDB Molecule:nad-dependent histone deacetylase sir2; PDBTitle: crystal structure of the sir2 deacetylase
109 | c3k35D_ |
| not modelled | 96.6 | 20 | PDB header:hydrolase Chain: D: PDB Molecule:nad-dependent deacetylase sirtuin-6; PDBTitle: crystal structure of human sirt6
110 | d1umdb1 |
| not modelled | 96.6 | 17 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Branched-chain alpha-keto acid dehydrogenase Pyr module
111 | d1j8fa_ |
| not modelled | 96.3 | 19 | Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators
112 | c2xt6B_ |
| not modelled | 96.3 | 16 | PDB header:lyase Chain: B: PDB Molecule:2-oxoglutarate decarboxylase; PDBTitle: crystal structure of mycobacterium smegmatis alpha-ketoglutarate2 decarboxylase homodimer (orthorhombic form)
113 | d1yc5a1 |
| not modelled | 96.3 | 17 | Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators
114 | c3pkiF_ |
| not modelled | 96.3 | 19 | PDB header:hydrolase Chain: F: PDB Molecule:nad-dependent deacetylase sirtuin-6; PDBTitle: human sirt6 crystal structure in complex with adp ribose
115 | d2b4ya1 |
| not modelled | 96.2 | 10 | Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators
116 | c1q14A_ |
| not modelled | 96.1 | 14 | PDB header:hydrolase Chain: A: PDB Molecule:hst2 protein; PDBTitle: structure and autoregulation of the yeast hst2 homolog of sir2
117 | d2ieaa1 |
| not modelled | 96.1 | 15 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:TK-like Pyr module
118 | d1s5pa_ |
| not modelled | 95.9 | 10 | Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators
119 | d1m2ka_ |
| not modelled | 95.7 | 14 | Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators
120 | d1q1aa_ |
| not modelled | 95.7 | 12 | Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0