Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP31441
DateThu Jan 5 11:47:32 GMT 2012
Unique Job ID52e1e8c69916f978

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3nqbB_
Top template information
PDB header:hydrolase
Chain: B: PDB Molecule:adenine deaminase 2;
PDBTitle: crystal structure of adenine deaminase from agrobacterium tumefaciens2 (str. c 58)
Confidence and coverage
Confidence:100.0% Coverage: 97%
573 residues ( 97% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MNNSINHKFHHISRAEYQELLAVSRGDAVADYIIDNVSILDLINGGEISGPIVIKGRYIA
Secondary structure 
SS confidence 
Disorder  ???????
?
?
?
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  GVGAEYTDAPALQRIDARGATAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVICDPH
Secondary structure 
SS confidence 
Disorder 
??
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  EIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCDVNGASFTLEQMLAWRDHPQV
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  TGLAEMMDYPGVISGQNALLDKLDAFRHLTLDGHCPGLGGKELNAYITAGIENCHESYQL
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  EEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNSPQCMLCTDDRNPWEIAHEGHIDAL
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  IRRLIEQHNVPLHVAYRVASWSTARHFGLNHLGLLAPGKQADIVLLSDARKVTVQQVLVK
Secondary structure 
SS confidence 
Disorder 
?
?
Disorder confidence 
 
   .........370.........380.........390.........400.........410.........420
Sequence  GEPIDAQTLQAEESARLAQSAPPYGNTIARQPVSASDFALQFTPGKRYRVIDVIHNELIT
Secondary structure 
SS confidence 
Disorder 
?
??????
?
??
??
Disorder confidence 
 
   .........430.........440.........450.........460.........470.........480
Sequence  HSHSSVYSENGFDRDDVSFIAVLERYGQRLAPACGLLGGFGLNEGALAATVSHDSHNIVV
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........490.........500.........510.........520.........530.........540
Sequence  IGRSAEEMALAVNQVIQDGGGLCVVRNGQVQSHLPLPIAGLMSTDTAQSLAEQIDALKAA
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........550.........560.........570.........580........
Sequence  ARECGPLPDEPFIQMAFLSLPVIPALKLTSQGLFDGEKFAFTTLEVTE
Secondary structure 
SS confidence 
Disorder 
??
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3nqb chain B

3D model

Region: 11 - 588
Aligned: 573
Modelled: 578
Confidence: 100.0%
Identity: 30%
PDB header:hydrolase
Chain: B: PDB Molecule:adenine deaminase 2;
PDBTitle: crystal structure of adenine deaminase from agrobacterium tumefaciens2 (str. c 58)

Phyre2

PDB 2aqo chain B

3D model

Region: 29 - 375
Aligned: 334
Modelled: 347
Confidence: 100.0%
Identity: 15%
PDB header:hydrolase
Chain: B: PDB Molecule:isoaspartyl dipeptidase;
PDBTitle: crystal structure of e. coli isoaspartyl dipeptidase mutant e77q

Phyre2

PDB 2paj chain A

3D model

Region: 30 - 371
Aligned: 336
Modelled: 342
Confidence: 100.0%
Identity: 17%
PDB header:hydrolase
Chain: A: PDB Molecule:putative cytosine/guanine deaminase;
PDBTitle: crystal structure of an amidohydrolase from an environmental sample of2 sargasso sea

Phyre2

PDB 2ubp chain C

3D model

Region: 23 - 446
Aligned: 417
Modelled: 419
Confidence: 100.0%
Identity: 19%
PDB header:hydrolase
Chain: C: PDB Molecule:protein (urease alpha subunit);
PDBTitle: structure of native urease from bacillus pasteurii

Phyre2

PDB 1xrf chain A

3D model

Region: 31 - 367
Aligned: 325
Modelled: 328
Confidence: 100.0%
Identity: 17%
PDB header:hydrolase
Chain: A: PDB Molecule:dihydroorotase;
PDBTitle: the crystal structure of a novel, latent dihydroorotase from aquifex2 aeolicus at 1.7 a resolution

Phyre2

PDB 2ftw chain A

3D model

Region: 30 - 389
Aligned: 350
Modelled: 360
Confidence: 100.0%
Identity: 13%
PDB header:hydrolase
Chain: A: PDB Molecule:dihydropyrimidine amidohydrolase;
PDBTitle: crystal structure of dihydropyrimidinase from dictyostelium discoideum

Phyre2

PDB 3lsb chain A

3D model

Region: 32 - 371
Aligned: 340
Modelled: 340
Confidence: 100.0%
Identity: 19%
PDB header:hydrolase
Chain: A: PDB Molecule:triazine hydrolase;
PDBTitle: crystal structure of the mutant e241q of atrazine chlorohydrolase trzn2 from arthrobacter aurescens tc1 complexed with zinc and ametrin

Phyre2

PDB 2gse chain C

3D model

Region: 32 - 392
Aligned: 351
Modelled: 361
Confidence: 100.0%
Identity: 16%
PDB header:hydrolase
Chain: C: PDB Molecule:dihydropyrimidinase-related protein 2;
PDBTitle: crystal structure of human dihydropyrimidinease-like 2

Phyre2

PDB 2vun chain C

3D model

Region: 32 - 376
Aligned: 339
Modelled: 341
Confidence: 100.0%
Identity: 21%
PDB header:hydrolase
Chain: C: PDB Molecule:enamidase;
PDBTitle: the crystal structure of enamidase at 1.9 a resolution - a2 new member of the amidohydrolase superfamily

Phyre2

PDB 2p50 chain C

3D model

Region: 32 - 367
Aligned: 333
Modelled: 336
Confidence: 100.0%
Identity: 17%
PDB header:hydrolase
Chain: C: PDB Molecule:n-acetylglucosamine-6-phosphate deacetylase;
PDBTitle: crystal structure of n-acetyl-d-glucosamine-6-phosphate deacetylase2 liganded with zn

Phyre2

PDB 3be7 chain B

3D model

Region: 31 - 367
Aligned: 327
Modelled: 336
Confidence: 100.0%
Identity: 18%
PDB header:hydrolase
Chain: B: PDB Molecule:zn-dependent arginine carboxypeptidase;
PDBTitle: crystal structure of zn-dependent arginine carboxypeptidase

Phyre2

PDB 2vr2 chain A

3D model

Region: 32 - 409
Aligned: 361
Modelled: 378
Confidence: 100.0%
Identity: 16%
PDB header:hydrolase
Chain: A: PDB Molecule:dihydropyrimidinase;
PDBTitle: human dihydropyrimidinase

Phyre2

PDB 3hpa chain B

3D model

Region: 31 - 371
Aligned: 335
Modelled: 338
Confidence: 100.0%
Identity: 17%
PDB header:hydrolase
Chain: B: PDB Molecule:amidohydrolase;
PDBTitle: crystal structure of an amidohydrolase gi:44264246 from an2 evironmental sample of sargasso sea

Phyre2

PDB 2gok chain A

3D model

Region: 30 - 365
Aligned: 334
Modelled: 336
Confidence: 100.0%
Identity: 18%
PDB header:hydrolase
Chain: A: PDB Molecule:imidazolonepropionase;
PDBTitle: crystal structure of the imidazolonepropionase from agrobacterium2 tumefaciens at 1.87 a resolution

Phyre2

PDB 2q09 chain A

3D model

Region: 30 - 365
Aligned: 334
Modelled: 336
Confidence: 100.0%
Identity: 17%
PDB header:hydrolase
Chain: A: PDB Molecule:imidazolonepropionase;
PDBTitle: crystal structure of imidazolonepropionase from environmental sample2 with bound inhibitor 3-(2,5-dioxo-imidazolidin-4-yl)-propionic acid

Phyre2

PDB 2vhl chain B

3D model

Region: 31 - 369
Aligned: 335
Modelled: 337
Confidence: 100.0%
Identity: 16%
PDB header:hydrolase
Chain: B: PDB Molecule:n-acetylglucosamine-6-phosphate deacetylase;
PDBTitle: the three-dimensional structure of the n-acetylglucosamine-2 6-phosphate deacetylase from bacillus subtilis

Phyre2

PDB 2ics chain A

3D model

Region: 30 - 367
Aligned: 325
Modelled: 333
Confidence: 100.0%
Identity: 19%
PDB header:hydrolase
Chain: A: PDB Molecule:adenine deaminase;
PDBTitle: crystal structure of an adenine deaminase

Phyre2

PDB 2bb0 chain A

3D model

Region: 28 - 367
Aligned: 338
Modelled: 340
Confidence: 100.0%
Identity: 17%
PDB header:hydrolase
Chain: A: PDB Molecule:imidazolonepropionase;
PDBTitle: structure of imidazolonepropionase from bacillus subtilis

Phyre2

PDB 1fwc chain C

3D model

Region: 24 - 383
Aligned: 348
Modelled: 359
Confidence: 100.0%
Identity: 18%
PDB header:hydrolase
Chain: C: PDB Molecule:urease;
PDBTitle: klebsiella aerogenes urease, c319a variant at ph 8.5

Phyre2

PDB 3dc8 chain B

3D model

Region: 32 - 376
Aligned: 328
Modelled: 343
Confidence: 100.0%
Identity: 17%
PDB header:hydrolase
Chain: B: PDB Molecule:dihydropyrimidinase;
PDBTitle: crystal structure of dihydropyrimidinase from sinorhizobium meliloti

Phyre2
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c3nqbB_
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c2aqoB_
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c2pajA_
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c2ubpC_
5
c1xrfA_
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c2ftwA_
7
c3lsbA_
8
c2gseC_
9
c2vunC_
10
c2p50C_
11
c3be7B_
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c2vr2A_
13
c3hpaB_
14
c2gokA_
15
c2q09A_
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c2vhlB_
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c2icsA_
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c2bb0A_
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c1fwcC_
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c3dc8B_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3nqbB_
100.0 30 PDB header:hydrolase
Chain: B: PDB Molecule:adenine deaminase 2;
PDBTitle: crystal structure of adenine deaminase from agrobacterium tumefaciens2 (str. c 58)
2c2aqoB_
100.0 15 PDB header:hydrolase
Chain: B: PDB Molecule:isoaspartyl dipeptidase;
PDBTitle: crystal structure of e. coli isoaspartyl dipeptidase mutant e77q
3c2pajA_
100.0 17 PDB header:hydrolase
Chain: A: PDB Molecule:putative cytosine/guanine deaminase;
PDBTitle: crystal structure of an amidohydrolase from an environmental sample of2 sargasso sea
4c2ubpC_
100.0 19 PDB header:hydrolase
Chain: C: PDB Molecule:protein (urease alpha subunit);
PDBTitle: structure of native urease from bacillus pasteurii
5c1xrfA_
100.0 17 PDB header:hydrolase
Chain: A: PDB Molecule:dihydroorotase;
PDBTitle: the crystal structure of a novel, latent dihydroorotase from aquifex2 aeolicus at 1.7 a resolution
6c2ftwA_
100.0 13 PDB header:hydrolase
Chain: A: PDB Molecule:dihydropyrimidine amidohydrolase;
PDBTitle: crystal structure of dihydropyrimidinase from dictyostelium discoideum
7c3lsbA_
100.0 19 PDB header:hydrolase
Chain: A: PDB Molecule:triazine hydrolase;
PDBTitle: crystal structure of the mutant e241q of atrazine chlorohydrolase trzn2 from arthrobacter aurescens tc1 complexed with zinc and ametrin
8c2gseC_
100.0 16 PDB header:hydrolase
Chain: C: PDB Molecule:dihydropyrimidinase-related protein 2;
PDBTitle: crystal structure of human dihydropyrimidinease-like 2
9c2vunC_
100.0 21 PDB header:hydrolase
Chain: C: PDB Molecule:enamidase;
PDBTitle: the crystal structure of enamidase at 1.9 a resolution - a2 new member of the amidohydrolase superfamily
10c2p50C_
100.0 17 PDB header:hydrolase
Chain: C: PDB Molecule:n-acetylglucosamine-6-phosphate deacetylase;
PDBTitle: crystal structure of n-acetyl-d-glucosamine-6-phosphate deacetylase2 liganded with zn
11c3be7B_
100.0 18 PDB header:hydrolase
Chain: B: PDB Molecule:zn-dependent arginine carboxypeptidase;
PDBTitle: crystal structure of zn-dependent arginine carboxypeptidase
12c2vr2A_
100.0 16 PDB header:hydrolase
Chain: A: PDB Molecule:dihydropyrimidinase;
PDBTitle: human dihydropyrimidinase
13c3hpaB_
100.0 17 PDB header:hydrolase
Chain: B: PDB Molecule:amidohydrolase;
PDBTitle: crystal structure of an amidohydrolase gi:44264246 from an2 evironmental sample of sargasso sea
14c2gokA_
100.0 18 PDB header:hydrolase
Chain: A: PDB Molecule:imidazolonepropionase;
PDBTitle: crystal structure of the imidazolonepropionase from agrobacterium2 tumefaciens at 1.87 a resolution
15c2q09A_
100.0 17 PDB header:hydrolase
Chain: A: PDB Molecule:imidazolonepropionase;
PDBTitle: crystal structure of imidazolonepropionase from environmental sample2 with bound inhibitor 3-(2,5-dioxo-imidazolidin-4-yl)-propionic acid
16c2vhlB_
100.0 16 PDB header:hydrolase
Chain: B: PDB Molecule:n-acetylglucosamine-6-phosphate deacetylase;
PDBTitle: the three-dimensional structure of the n-acetylglucosamine-2 6-phosphate deacetylase from bacillus subtilis
17c2icsA_
100.0 19 PDB header:hydrolase
Chain: A: PDB Molecule:adenine deaminase;
PDBTitle: crystal structure of an adenine deaminase
18c2bb0A_
100.0 17 PDB header:hydrolase
Chain: A: PDB Molecule:imidazolonepropionase;
PDBTitle: structure of imidazolonepropionase from bacillus subtilis
19c1fwcC_
100.0 18 PDB header:hydrolase
Chain: C: PDB Molecule:urease;
PDBTitle: klebsiella aerogenes urease, c319a variant at ph 8.5
20c3dc8B_
100.0 17 PDB header:hydrolase
Chain: B: PDB Molecule:dihydropyrimidinase;
PDBTitle: crystal structure of dihydropyrimidinase from sinorhizobium meliloti
21c1gkrA_
not modelled 100.0 20 PDB header:hydrolase
Chain: A: PDB Molecule:non-atp dependent l-selective hydantoinase;
PDBTitle: l-hydantoinase (dihydropyrimidinase) from arthrobacter2 aurescens
22c1gkpD_
not modelled 100.0 21 PDB header:hydrolase
Chain: D: PDB Molecule:hydantoinase;
PDBTitle: d-hydantoinase (dihydropyrimidinase) from thermus sp. in2 space group c2221
23c3gipB_
not modelled 100.0 23 PDB header:hydrolase
Chain: B: PDB Molecule:n-acyl-d-glutamate deacylase;
PDBTitle: crystal structure of n-acyl-d-glutamate deacylase from2 bordetella bronchiseptica complexed with zinc, acetate and3 formate ions.
24c3gnhA_
not modelled 100.0 15 PDB header:hydrolase
Chain: A: PDB Molecule:l-lysine, l-arginine carboxypeptidase cc2672;
PDBTitle: crystal structure of l-lysine, l-arginine carboxypeptidase cc2672 from2 caulobacter crescentus cb15 complexed with n-methyl phosphonate3 derivative of l-arginine.
25c1e9yB_
not modelled 100.0 19 PDB header:hydrolase
Chain: B: PDB Molecule:urease subunit beta;
PDBTitle: crystal structure of helicobacter pylori urease in complex with2 acetohydroxamic acid
26c3la4A_
not modelled 100.0 17 PDB header:hydrolase
Chain: A: PDB Molecule:urease;
PDBTitle: crystal structure of the first plant urease from jack bean (canavalia2 ensiformis)
27c3d6nA_
not modelled 100.0 17 PDB header:hydrolase/transferase
Chain: A: PDB Molecule:dihydroorotase;
PDBTitle: crystal structure of aquifex dihydroorotase activated by aspartate2 transcarbamoylase
28c2fvmA_
not modelled 100.0 16 PDB header:hydrolase
Chain: A: PDB Molecule:dihydropyrimidinase;
PDBTitle: crystal structure of dihydropyrimidinase from saccharomyces kluyveri2 in complex with the reaction product n-carbamyl-beta-alanine
29c2r8cB_
not modelled 100.0 16 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative amidohydrolase;
PDBTitle: crystal structure of uncharacterized protein eaj56179
30c2gwnA_
not modelled 100.0 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:dihydroorotase;
PDBTitle: the structure of putative dihydroorotase from porphyromonas2 gingivalis.
31c1k1dF_
not modelled 100.0 20 PDB header:hydrolase
Chain: F: PDB Molecule:d-hydantoinase;
PDBTitle: crystal structure of d-hydantoinase
32c3lnpA_
not modelled 100.0 15 PDB header:hydrolase
Chain: A: PDB Molecule:amidohydrolase family protein olei01672_1_465;
PDBTitle: crystal structure of amidohydrolase family protein2 olei01672_1_465 from oleispira antarctica
33c1nfgA_
not modelled 100.0 21 PDB header:hydrolase
Chain: A: PDB Molecule:d-hydantoinase;
PDBTitle: structure of d-hydantoinase
34c1rjqA_
not modelled 100.0 21 PDB header:hydrolase
Chain: A: PDB Molecule:d-aminoacylase;
PDBTitle: the crystal structure of the d-aminoacylase mutant d366a
35c3egjA_
not modelled 100.0 16 PDB header:hydrolase
Chain: A: PDB Molecule:n-acetylglucosamine-6-phosphate deacetylase;
PDBTitle: n-acetylglucosamine-6-phosphate deacetylase from vibrio cholerae.
36c2p9bA_
not modelled 100.0 16 PDB header:hydrolase
Chain: A: PDB Molecule:possible prolidase;
PDBTitle: crystal structure of putative prolidase from2 bifidobacterium longum
37c1o12B_
not modelled 100.0 17 PDB header:hydrolase
Chain: B: PDB Molecule:n-acetylglucosamine-6-phosphate deacetylase;
PDBTitle: crystal structure of n-acetylglucosamine-6-phosphate2 deacetylase (tm0814) from thermotoga maritima at 2.5 a3 resolution
38c3feqB_
not modelled 100.0 19 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative amidohydrolase;
PDBTitle: crystal structure of uncharacterized protein eah89906
39c1p1mA_
not modelled 100.0 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein tm0936;
PDBTitle: structure of thermotoga maritima amidohydrolase tm09362 bound to ni and methionine
40c3hm7A_
not modelled 100.0 18 PDB header:hydrolase
Chain: A: PDB Molecule:allantoinase;
PDBTitle: crystal structure of allantoinase from bacillus halodurans c-125
41c2qt3A_
not modelled 100.0 19 PDB header:hydrolase
Chain: A: PDB Molecule:n-isopropylammelide isopropyl amidohydrolase;
PDBTitle: crystal structure of n-isopropylammelide isopropylaminohydrolase atzc2 from pseudomonas sp. strain adp complexed with zn
42c2z00A_
not modelled 100.0 20 PDB header:hydrolase
Chain: A: PDB Molecule:dihydroorotase;
PDBTitle: crystal structure of dihydroorotase from thermus thermophilus
43c3ooqC_
not modelled 100.0 15 PDB header:hydrolase
Chain: C: PDB Molecule:amidohydrolase;
PDBTitle: crystal structure of amidohydrolase from thermotoga maritima msb8
44c3griB_
not modelled 100.0 17 PDB header:hydrolase
Chain: B: PDB Molecule:dihydroorotase;
PDBTitle: the crystal structure of a dihydroorotase from staphylococcus aureus
45c3mpgB_
not modelled 100.0 19 PDB header:hydrolase
Chain: B: PDB Molecule:dihydroorotase;
PDBTitle: dihydroorotase from bacillus anthracis
46c3e74D_
not modelled 100.0 21 PDB header:hydrolase
Chain: D: PDB Molecule:allantoinase;
PDBTitle: crystal structure of e. coli allantoinase with iron ions at2 the metal center
47c2ogjB_
not modelled 100.0 17 PDB header:hydrolase
Chain: B: PDB Molecule:dihydroorotase;
PDBTitle: crystal structure of a dihydroorotase
48c2i9uA_
not modelled 100.0 15 PDB header:hydrolase
Chain: A: PDB Molecule:cytosine/guanine deaminase related protein;
PDBTitle: crystal structure of guanine deaminase from c. acetobutylicum with2 bound guanine in the active site
49c3e0lB_
not modelled 100.0 15 PDB header:hydrolase
Chain: B: PDB Molecule:guanine deaminase;
PDBTitle: computationally designed ammelide deaminase
50c2qs8A_
not modelled 100.0 17 PDB header:hydrolase
Chain: A: PDB Molecule:xaa-pro dipeptidase;
PDBTitle: crystal structure of a xaa-pro dipeptidase with bound2 methionine in the active site
51c3v7pA_
not modelled 100.0 16 PDB header:hydrolase
Chain: A: PDB Molecule:amidohydrolase family protein;
PDBTitle: crystal structure of amidohydrolase nis_0429 (target efi-500396) from2 nitratiruptor sp. sb155-2
52c2oodA_
not modelled 100.0 17 PDB header:hydrolase
Chain: A: PDB Molecule:blr3880 protein;
PDBTitle: crystal structure of guanine deaminase from bradyrhizobium japonicum
53c1r9yA_
not modelled 100.0 14 PDB header:hydrolase
Chain: A: PDB Molecule:cytosine deaminase;
PDBTitle: bacterial cytosine deaminase d314a mutant.
54c3mduA_
not modelled 100.0 17 PDB header:hydrolase
Chain: A: PDB Molecule:n-formimino-l-glutamate iminohydrolase;
PDBTitle: the structure of n-formimino-l-glutamate iminohydrolase from2 pseudomonas aeruginosa complexed with n-guanidino-l-glutamate
55c3ighX_
not modelled 100.0 16 PDB header:hydrolase
Chain: X: PDB Molecule:uncharacterized metal-dependent hydrolase;
PDBTitle: crystal structure of an uncharacterized metal-dependent2 hydrolase from pyrococcus horikoshii ot3
56c3etkA_
not modelled 100.0 16 PDB header:hydrolase
Chain: A: PDB Molecule:uncharacterized metal-dependent hydrolase;
PDBTitle: crystal structure of an uncharacterized metal-dependent2 hydrolase from pyrococcus furiosus
57c2imrA_
not modelled 100.0 18 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein dr_0824;
PDBTitle: crystal structure of amidohydrolase dr_0824 from2 deinococcus radiodurans
58d2icsa2
not modelled 99.9 15 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Adenine deaminase-like
59c3msrA_
not modelled 99.9 14 PDB header:hydrolase
Chain: A: PDB Molecule:amidohydrolases;
PDBTitle: the crystal structure of an amidohydrolase from mycoplasma synoviae
60d1onwa2
not modelled 99.9 15 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Isoaspartyl dipeptidase, catalytic domain
61d1o12a2
not modelled 99.8 14 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain
62d2paja2
not modelled 99.8 13 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:SAH/MTA deaminase-like
63d1xrta2
not modelled 99.8 16 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Hydantoinase (dihydropyrimidinase), catalytic domain
64d1kcxa2
not modelled 99.8 17 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Hydantoinase (dihydropyrimidinase), catalytic domain
65d4ubpc2
not modelled 99.8 16 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:alpha-subunit of urease, catalytic domain
66d1ynya2
not modelled 99.8 18 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Hydantoinase (dihydropyrimidinase), catalytic domain
67d3be7a2
not modelled 99.8 15 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Zn-dependent arginine carboxypeptidase-like
68d2p9ba2
not modelled 99.8 15 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Imidazolonepropionase-like
69d2ftwa2
not modelled 99.8 16 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Hydantoinase (dihydropyrimidinase), catalytic domain
70d1gkpa2
not modelled 99.8 20 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Hydantoinase (dihydropyrimidinase), catalytic domain
71d1un7a2
not modelled 99.8 18 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain
72c3pnuA_
not modelled 99.7 12 PDB header:hydrolase
Chain: A: PDB Molecule:dihydroorotase;
PDBTitle: 2.4 angstrom crystal structure of dihydroorotase (pyrc) from2 campylobacter jejuni.
73d1e9yb1
not modelled 99.7 23 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:alpha-Subunit of urease
74d2ooda2
not modelled 99.7 15 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:SAH/MTA deaminase-like
75d2bb0a2
not modelled 99.7 15 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Imidazolonepropionase-like
76d1yrra2
not modelled 99.7 18 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain
77d1k1da2
not modelled 99.7 18 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Hydantoinase (dihydropyrimidinase), catalytic domain
78d2qs8a2
not modelled 99.7 15 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Zn-dependent arginine carboxypeptidase-like
79d1ejxc1
not modelled 99.7 23 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:alpha-Subunit of urease
80d2i9ua2
not modelled 99.7 14 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:SAH/MTA deaminase-like
81d2uz9a2
not modelled 99.7 15 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:SAH/MTA deaminase-like
82d1i0da_
not modelled 99.7 14 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Phosphotriesterase-like
83d2puza2
not modelled 99.7 16 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Imidazolonepropionase-like
84d1nfga2
not modelled 99.7 20 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Hydantoinase (dihydropyrimidinase), catalytic domain
85c3ggmB_
not modelled 99.7 27 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein bt9727_2919;
PDBTitle: crystal structure of bt9727_2919 from bacillus2 thuringiensis subsp. northeast structural genomics target3 bur228b
86d2r8ca2
not modelled 99.7 16 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Zn-dependent arginine carboxypeptidase-like
87d2eg6a1
not modelled 99.7 12 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Dihydroorotase
88d1ra0a2
not modelled 99.7 12 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Cytosine deaminase catalytic domain
89d2q09a2
not modelled 99.7 16 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Imidazolonepropionase-like
90d1onwa1
not modelled 99.6 17 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:Isoaspartyl dipeptidase
91c3jzeC_
not modelled 99.6 10 PDB header:hydrolase
Chain: C: PDB Molecule:dihydroorotase;
PDBTitle: 1.8 angstrom resolution crystal structure of dihydroorotase (pyrc)2 from salmonella enterica subsp. enterica serovar typhimurium str. lt2
92d2fvka1
not modelled 99.6 28 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:Hydantoinase (dihydropyrimidinase)
93c1pscA_
not modelled 99.6 14 PDB header:hydrolase
Chain: A: PDB Molecule:phosphotriesterase;
PDBTitle: phosphotriesterase from pseudomonas diminuta
94d2d2ja1
not modelled 99.6 15 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Phosphotriesterase-like
95d1gkra2
not modelled 99.6 19 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Hydantoinase (dihydropyrimidinase), catalytic domain
96d2imra2
not modelled 99.6 15 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:DR0824-like
97d2r8ca1
not modelled 99.6 22 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:Zn-dependent arginine carboxypeptidase-like
98c2zc1A_
not modelled 99.6 18 PDB header:hydrolase
Chain: A: PDB Molecule:phosphotriesterase;
PDBTitle: organophosphorus hydrolase from deinococcus radiodurans
99d1yixa1
not modelled 99.5 12 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:TatD Mg-dependent DNase-like
100d2fvka2
not modelled 99.5 17 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Hydantoinase (dihydropyrimidinase), catalytic domain
101c3pnzD_
not modelled 99.5 13 PDB header:hydrolase
Chain: D: PDB Molecule:phosphotriesterase family protein;
PDBTitle: crystal structure of the lactonase lmo2620 from listeria monocytogenes
102d1yrra1
not modelled 99.5 15 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:N-acetylglucosamine-6-phosphate deacetylase, NagA
103d2p9ba1
not modelled 99.5 11 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:Imidazolonepropionase-like
104d1p1ma2
not modelled 99.4 11 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:SAH/MTA deaminase-like
105d1bf6a_
not modelled 99.4 12 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Phosphotriesterase-like
106d1zzma1
not modelled 99.4 17 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:TatD Mg-dependent DNase-like
107c3f4cA_
not modelled 99.4 17 PDB header:hydrolase
Chain: A: PDB Molecule:organophosphorus hydrolase;
PDBTitle: crystal structure of organophosphorus hydrolase from geobacillus2 stearothermophilus strain 10, with glycerol bound
108c2vc7A_
not modelled 99.4 13 PDB header:hydrolase
Chain: A: PDB Molecule:aryldialkylphosphatase;
PDBTitle: structural basis for natural lactonase and promiscuous2 phosphotriesterase activities
109d1m7ja1
not modelled 99.4 29 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:D-aminoacylase
110d2ftwa1
not modelled 99.3 11 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:Hydantoinase (dihydropyrimidinase)
111d1k1da1
not modelled 99.3 23 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:Hydantoinase (dihydropyrimidinase)
112c3rcmA_
not modelled 99.3 12 PDB header:hydrolase
Chain: A: PDB Molecule:tatd family hydrolase;
PDBTitle: crystal structure of efi target 500140:tatd family hydrolase from2 pseudomonas putida
113d1xwya1
not modelled 99.2 11 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:TatD Mg-dependent DNase-like
114c2y1hA_
not modelled 99.2 11 PDB header:hydrolase
Chain: A: PDB Molecule:putative deoxyribonuclease tatdn3;
PDBTitle: crystal structure of the human tatd-domain protein 3 (tatdn3)
115d1gkpa1
not modelled 99.2 28 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:Hydantoinase (dihydropyrimidinase)
116d1j6oa_
not modelled 99.2 13 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:TatD Mg-dependent DNase-like
117d1ynya1
not modelled 99.2 18 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:Hydantoinase (dihydropyrimidinase)
118d1m7ja3
not modelled 99.2 19 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:D-aminoacylase, catalytic domain
119d1kcxa1
not modelled 99.1 13 Fold:Composite domain of metallo-dependent hydrolases
Superfamily:Composite domain of metallo-dependent hydrolases
Family:Hydantoinase (dihydropyrimidinase)
120c3rhgA_
not modelled 99.1 16 PDB header:hydrolase
Chain: A: PDB Molecule:putative phophotriesterase;
PDBTitle: crystal structure of amidohydrolase pmi1525 (target efi-500319) from2 proteus mirabilis hi4320

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0