BLASTP 2.2.22 [Sep-27-2009]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= batch____
         (354 letters)

Database: uniref50.fasta 
           3,077,464 sequences; 1,040,396,356 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_A1AHM5 Protein cbrA n=54 Tax=Enterobacteriaceae RepID=C...   724   0.0  
UniRef50_B6ZQD5 Protein CbrA n=1 Tax=Escherichia coli O157:H7 st...   665   0.0  
UniRef50_D2THX1 Putative uncharacterized protein n=4 Tax=Bacteri...   618   e-175
UniRef50_C3KYD3 CbrA protein n=14 Tax=Bacteria RepID=C3KYD3_CLOB6     386   e-106
UniRef50_UPI00019786F4 putative oxidoreductase n=1 Tax=Helicobac...   295   1e-78
UniRef50_Q7VFG9 Putative uncharacterized protein n=1 Tax=Helicob...   288   2e-76
UniRef50_B8FUH4 FAD dependent oxidoreductase n=3 Tax=Clostridial...   237   5e-61
UniRef50_C6JQS4 FAD dependent oxidoreductase n=1 Tax=Fusobacteri...   190   7e-47
UniRef50_Q1PX22 Putative uncharacterized protein n=1 Tax=Candida...    86   3e-15
UniRef50_A6QA88 Geranylgeranyl hydrogenase n=1 Tax=Sulfurovum sp...    83   2e-14
UniRef50_B5YGK5 Geranylgeranyl hydrogenase, putative n=1 Tax=The...    71   6e-11
UniRef50_B9M019 FAD dependent oxidoreductase n=1 Tax=Geobacter s...    70   2e-10
UniRef50_B9L6H5 Geranylgeranyl hydrogenase n=2 Tax=Nautiliaceae ...    69   2e-10
UniRef50_P26172 Geranylgeranyl diphosphate reductase n=34 Tax=Ba...    68   5e-10
UniRef50_B5W6L5 Geranylgeranyl reductase n=2 Tax=Arthrospira Rep...    63   2e-08
UniRef50_Q1IMS5 Geranylgeranyl reductase n=1 Tax=Candidatus Kori...    62   3e-08
UniRef50_P96800 Uncharacterized protein Mbar_A1602 n=1 Tax=Metha...    61   7e-08
UniRef50_Q6ALA8 Related to dehydrogenases (Flavoproteins) n=1 Ta...    60   2e-07
UniRef50_B1LSG8 Geranylgeranyl reductase n=27 Tax=Proteobacteria...    60   2e-07
UniRef50_D1RCG6 Geranylgeranyl reductase family protein n=1 Tax=...    59   2e-07
UniRef50_Q649G8 Geranylgeranyl reductase n=3 Tax=environmental s...    59   2e-07
UniRef50_B3QZ41 Geranylgeranyl reductase n=12 Tax=Chlorobiaceae ...    57   9e-07
UniRef50_B0JID7 Geranylgeranyl reductase n=8 Tax=Cyanobacteria R...    55   5e-06
UniRef50_A5D4V1 Dehydrogenases n=1 Tax=Pelotomaculum thermopropi...    54   7e-06
UniRef50_C6CUN6 Monooxygenase FAD-binding n=1 Tax=Paenibacillus ...    54   9e-06
UniRef50_A8M2V9 Geranylgeranyl reductase n=5 Tax=Actinomycetales...    54   9e-06
UniRef50_Q9R5Z2 SSB16=(GAL4(1-147))-SSB16 transcriptional repres...    54   1e-05
UniRef50_A3V9M1 Geranylgeranyl reductase n=1 Tax=Rhodobacterales...    54   1e-05
UniRef50_UPI0000D53425 oxidoreductase n=1 Tax=Psychroflexus torq...    54   1e-05
UniRef50_Q2NER9 Digeranylgeranylglycerophospholipid reductase 3 ...    52   2e-05
UniRef50_A0B5F9 Geranylgeranyl reductase n=1 Tax=Methanosaeta th...    52   3e-05
UniRef50_B3ECC8 Geranylgeranyl reductase n=3 Tax=Chlorobium RepI...    52   3e-05
UniRef50_Q2S264 FAD dependent oxidoreductase, putative n=1 Tax=S...    51   6e-05
UniRef50_O29786 Digeranylgeranylglycerophospholipid reductase n=...    50   1e-04
UniRef50_UPI0001C42077 geranylgeranyl reductase family protein n...    50   1e-04
UniRef50_Q8TMB3 Putative uncharacterized protein n=1 Tax=Methano...    50   1e-04
UniRef50_A6CDB5 Geranylgeranyl reductase n=1 Tax=Planctomyces ma...    50   2e-04
UniRef50_C0GUA1 Geranylgeranyl reductase n=1 Tax=Desulfonatronos...    49   2e-04
UniRef50_C3NB54 FAD dependent oxidoreductase n=12 Tax=Sulfolobac...    49   3e-04
UniRef50_A8ME14 Geranylgeranyl reductase n=1 Tax=Caldivirga maqu...    49   3e-04
UniRef50_UPI0001C421FD hypothetical protein BpOF4_18960 n=1 Tax=...    48   4e-04
UniRef50_Q8DGN7 Tlr2279 protein n=5 Tax=Cyanobacteria RepID=Q8DG...    48   6e-04
UniRef50_Q3A1Y0 Flavoprotein-containing dehydrogenase n=1 Tax=Pe...    47   0.001
UniRef50_B8GFT3 Geranylgeranyl reductase n=1 Tax=Methanosphaerul...    47   0.002
UniRef50_Q11W52 Probable electron transfer flavoprotein n=1 Tax=...    46   0.002
UniRef50_A6GD06 Geranylgeranyl reductase n=1 Tax=Plesiocystis pa...    46   0.002
UniRef50_C7YZG9 Putative uncharacterized protein n=2 Tax=Nectria...    46   0.003
UniRef50_C6A374 Geranylgeranyl hydrogenase n=9 Tax=Thermococcace...    45   0.004
UniRef50_UPI000038E1B1 geranylgeranyl hydrogenase n=1 Tax=Ferrop...    45   0.004
UniRef50_A3CSH0 Geranylgeranyl reductase n=1 Tax=Methanoculleus ...    45   0.004
UniRef50_B5MAB8 Putative salicylate 1-monooxygenase n=1 Tax=Rhod...    45   0.005
UniRef50_C6PBK9 Geranylgeranyl reductase n=1 Tax=Thermoanaerobac...    44   0.007
UniRef50_C1RER8 2-polyprenyl-6-methoxyphenol hydroxylase-like ox...    44   0.010
UniRef50_B4U8N3 Geranylgeranyl reductase n=1 Tax=Hydrogenobaculu...    44   0.011
UniRef50_C9NII0 Monooxygenase FAD-binding n=1 Tax=Streptomyces f...    44   0.012
UniRef50_A7IDT6 Monooxygenase FAD-binding n=9 Tax=Proteobacteria...    43   0.017
UniRef50_Q6KZ83 FixC protein n=1 Tax=Picrophilus torridus RepID=...    43   0.021
UniRef50_A1RY40 Geranylgeranyl reductase n=1 Tax=Thermofilum pen...    42   0.023
UniRef50_O26377 Digeranylgeranylglycerophospholipid reductase 1 ...    42   0.028
UniRef50_B2HF07 3-(3-hydroxy-phenyl) propionate hydroxylase n=6 ...    42   0.029
UniRef50_D2RGA8 Dehydrogenase (Flavoprotein)-like protein n=1 Ta...    42   0.030
UniRef50_Q2RLB4 Geranylgeranyl reductase n=1 Tax=Moorella thermo...    41   0.063

>UniRef50_A1AHM5 Protein cbrA n=54 Tax=Enterobacteriaceae RepID=CBRA_ECOK1
          Length = 366

 Score =  724 bits (1870), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 347/354 (98%), Positives = 350/354 (98%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQ GTEGFSKPCGGLLAPDAQRSFIR
Sbjct: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQHGTEGFSKPCGGLLAPDAQRSFIR 60

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD 120
           DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD
Sbjct: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD 120

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW 180
           SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW
Sbjct: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW 180

Query: 181 FAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ 240
           FAEKHPVPFYSCIFDN+IT+CYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ
Sbjct: 181 FAEKHPVPFYSCIFDNAITDCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ 240

Query: 241 FGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVL 300
           FGK VKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDS +ILRSVL
Sbjct: 241 FGKAVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSAEILRSVL 300

Query: 301 LKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAHIPQLKD 354
           LK PEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAHIPQLKD
Sbjct: 301 LKLPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAHIPQLKD 354


>UniRef50_B6ZQD5 Protein CbrA n=1 Tax=Escherichia coli O157:H7 str. TW14588
           RepID=B6ZQD5_ECO57
          Length = 374

 Score =  665 bits (1717), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 318/328 (96%), Positives = 323/328 (98%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQ GTEGFSKPCGGLLAPDAQRSFIR
Sbjct: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQHGTEGFSKPCGGLLAPDAQRSFIR 60

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD 120
           DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD
Sbjct: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD 120

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW 180
           SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRR+LYPDHQIRKYVAIQQW
Sbjct: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRYLYPDHQIRKYVAIQQW 180

Query: 181 FAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ 240
           FAEKHPVPFYSCIFDN+IT+CYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ
Sbjct: 181 FAEKHPVPFYSCIFDNAITDCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ 240

Query: 241 FGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVL 300
           FGK VKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDS +ILRSVL
Sbjct: 241 FGKAVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSAEILRSVL 300

Query: 301 LKQPEKLNTAYWRATRKLRLKLFGKIVK 328
           LKQPEK+N AYW ATRKLRLKLFGKIVK
Sbjct: 301 LKQPEKINAAYWHATRKLRLKLFGKIVK 328


>UniRef50_D2THX1 Putative uncharacterized protein n=4 Tax=Bacteria
           RepID=D2THX1_CITRO
          Length = 380

 Score =  618 bits (1593), Expect = e-175,   Method: Compositional matrix adjust.
 Identities = 289/354 (81%), Positives = 317/354 (89%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           MEHFDVAIIGLGPAG+ALARKL+GKMQVIALDKK QCG EGF+KPCGGLLAPDAQR+FIR
Sbjct: 1   MEHFDVAIIGLGPAGAALARKLSGKMQVIALDKKRQCGNEGFTKPCGGLLAPDAQRAFIR 60

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD 120
           DGLTLPVDVIANPQIFSVKT+DV ASL RNYQRSYININRHAFDLW+KSLIP  V VYHD
Sbjct: 61  DGLTLPVDVIANPQIFSVKTIDVEASLERNYQRSYININRHAFDLWLKSLIPDDVRVYHD 120

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW 180
           SLCRKIWRE+DKWH+IFRADG EQ +T RYLVGADGANS+VRR+LYP HQIRKYVAIQQW
Sbjct: 121 SLCRKIWREEDKWHIIFRADGQEQKVTTRYLVGADGANSLVRRYLYPQHQIRKYVAIQQW 180

Query: 181 FAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ 240
           FAE HPVPFYSCIFDN+IT+CYSWSISKDGYFIFGGAYPMKDGQ RF  LK KM AFQF+
Sbjct: 181 FAESHPVPFYSCIFDNAITDCYSWSISKDGYFIFGGAYPMKDGQARFEALKAKMEAFQFR 240

Query: 241 FGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVL 300
           FG  +KSEKCTVLFPSRW+DFVCGKDNAFLIGEAAGFISASSLEGISYALDS D L +VL
Sbjct: 241 FGNPLKSEKCTVLFPSRWKDFVCGKDNAFLIGEAAGFISASSLEGISYALDSADRLNAVL 300

Query: 301 LKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAHIPQLKD 354
            +     N+AY + TR+LR+KL+GKI+KSR LT+   RK +M+SGVAHIP  +D
Sbjct: 301 TRHAADKNSAYRKVTRQLRIKLYGKILKSRILTSALTRKRVMQSGVAHIPLAQD 354


>UniRef50_C3KYD3 CbrA protein n=14 Tax=Bacteria RepID=C3KYD3_CLOB6
          Length = 364

 Score =  386 bits (992), Expect = e-106,   Method: Compositional matrix adjust.
 Identities = 185/346 (53%), Positives = 247/346 (71%), Gaps = 1/346 (0%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           +D+AIIGLGP+GS LA+ L+ K +VIA+DKK+    +GF KPCGGLL+ DAQ++  +  +
Sbjct: 9   YDIAIIGLGPSGSVLAQLLSKKHKVIAIDKKNSI-EKGFKKPCGGLLSSDAQKALAKLDI 67

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLC 123
           TLP DV+ +PQIF+VKT+++  +L R YQR YIN++RH FDLW+KSLIP  VEVY +S C
Sbjct: 68  TLPKDVMVDPQIFAVKTIELKNALIRYYQRFYINLDRHKFDLWLKSLIPNHVEVYSNSYC 127

Query: 124 RKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAE 183
             + +  + + V F   G +Q I  +YLVGADGANS+VRR LYP  +IR Y++IQQWF+E
Sbjct: 128 SSVEKIPEGYRVTFYEKGVKQVIITKYLVGADGANSLVRRSLYPKKKIRTYMSIQQWFSE 187

Query: 184 KHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGK 243
            H  PFYSCIFD   T+C SWSISKD  FIFGGA+P+ + + RF   K+K+    F+FGK
Sbjct: 188 THDNPFYSCIFDLENTDCCSWSISKDNKFIFGGAFPIHNSRKRFENQKKKLEKIGFRFGK 247

Query: 244 TVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQ 303
            +K+E C VL PS + DF CGK+NAFL+GEAAGFIS SSLEGIS A++S  +L  VL   
Sbjct: 248 PIKTEACMVLRPSAFYDFCCGKENAFLVGEAAGFISPSSLEGISSAINSARVLSEVLNTH 307

Query: 304 PEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAHI 349
            +  N  YW  T  +RLK+F K++K   +  P LRK +++SG+  I
Sbjct: 308 SKDPNKKYWLKTFNIRLKIFLKLLKCPFMYNPFLRKLVLKSGLKSI 353


>UniRef50_UPI00019786F4 putative oxidoreductase n=1 Tax=Helicobacter cinaedi CCUG 18818
           RepID=UPI00019786F4
          Length = 389

 Score =  295 bits (755), Expect = 1e-78,   Method: Compositional matrix adjust.
 Identities = 157/364 (43%), Positives = 219/364 (60%), Gaps = 19/364 (5%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQ---CGTEGFSKPCGGLLAPDAQRS 57
           +  FD+AIIGLG AGS LA  L   ++VIA+DKK     C  E F KPCGGLL+   Q++
Sbjct: 14  LGEFDIAIIGLGVAGSNLASLLQSHLKVIAIDKKDSSGDCFDESFHKPCGGLLSEGGQKA 73

Query: 58  FIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEV 117
           F   GL LP  ++  PQIF++ T+D         Q+ YIN+ RHAFDLW KS IP+ +  
Sbjct: 74  FATQGLNLPTRLLVEPQIFAINTIDYGYPHASYIQKGYINMERHAFDLWQKSRIPSHIST 133

Query: 118 YHDSLCRKIWREDDKWHVIF--RADGWEQHIT------ARYLVGADGANSMVRRHLYPDH 169
           +H +  + + + ++  + +   R D     I+      A+ ++GADGA S +RR+LYP  
Sbjct: 134 FHKAYFKSLKQGENGIYTLHFKRQDSKNAKISQDFTCKAKIIIGADGAKSHLRRYLYPQL 193

Query: 170 QIRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTT 229
           + +  V IQ+W+ E H  P  SC+FD  +T  YSWS+SK+GYFIFGGAYP  + Q RF T
Sbjct: 194 KTKSLVCIQEWYKE-HNAPMLSCVFDKELTPSYSWSMSKNGYFIFGGAYPHANCQERFAT 252

Query: 230 LKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYA 289
             E++    F FGK +K E C VL P+R +DFV G    FLIGEAAGFI+AS+LEGIS A
Sbjct: 253 QIERLRTLGFIFGKPLKKEACLVLQPTRLKDFVLGHSGVFLIGEAAGFINASTLEGISGA 312

Query: 290 LDSTDILRSVL------LKQPEKLNTAYWRATRKLRLK-LFGKIVKSRCLTAPALRKWIM 342
           ++S+ IL  +L      + +   L+ AY    R L +K LF   V+   +  P +R+ I+
Sbjct: 313 MNSSRILAHILNACDMNVSRTSTLHRAYRAKARMLIVKTLFRHYVRYPFMFVPCIRRLIL 372

Query: 343 RSGV 346
           R G+
Sbjct: 373 RFGL 376


>UniRef50_Q7VFG9 Putative uncharacterized protein n=1 Tax=Helicobacter hepaticus
           RepID=Q7VFG9_HELHP
          Length = 384

 Score =  288 bits (736), Expect = 2e-76,   Method: Compositional matrix adjust.
 Identities = 160/368 (43%), Positives = 220/368 (59%), Gaps = 23/368 (6%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKH---QCGTEGFSKPCGGLLAPDAQRSFIR 60
           +D+AIIGLG AGS LA  L   ++VIA+DKK     C  E F KPCGGLL+  AQ++F  
Sbjct: 8   YDIAIIGLGVAGSNLAALLNLHLKVIAVDKKDIQGHCNDEHFHKPCGGLLSQGAQKAFAM 67

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD 120
            GL LP  ++ANPQIF++ T+D         Q++YIN+ RH FDLW+KSLIP  +  +H 
Sbjct: 68  QGLNLPNTLLANPQIFAINTIDWHYPYASYIQKAYINMERHRFDLWLKSLIPPHIHTFHK 127

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHIT----ARYLVGADGANSMVRRHLYPDHQIRKYVA 176
           +  ++I ++   + + F  +   QHI+    AR ++GADGA S +RR LYP  +I   V 
Sbjct: 128 AYFKRIEQKQGFYTIYFTQEQDSQHISYHCNARLVIGADGAKSHIRRWLYPQLKIPSLVC 187

Query: 177 IQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSA 236
           IQ+WF E       SCIFD  ++  YSWS+SKD YFIFGGAYP K  +  F T KE++  
Sbjct: 188 IQEWFKES-TNSMLSCIFDKELSPSYSWSMSKDEYFIFGGAYPHKQCKRAFATQKERLKN 246

Query: 237 FQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDIL 296
             F FG+  K E C VL P+RW+DFV G    FL+GEAAGFI+AS+LEGIS A++S+ IL
Sbjct: 247 LGFIFGQPFKREACLVLTPTRWRDFVQGHSGVFLVGEAAGFINASTLEGISGAMNSSRIL 306

Query: 297 RSVLLKQP--------------EKLNTAYWRATRKLRLK-LFGKIVKSRCLTAPALRKWI 341
             +L  +               + L+  Y + TR L  K L    V+   +  P  R++I
Sbjct: 307 SEILNNEEFNALSRNKDIALWYKLLHRTYTKRTRFLVCKTLLRHYVRYPFMFIPLFRRFI 366

Query: 342 MRSGVAHI 349
           +R G+  +
Sbjct: 367 LRFGILRV 374


>UniRef50_B8FUH4 FAD dependent oxidoreductase n=3 Tax=Clostridiales
           RepID=B8FUH4_DESHD
          Length = 356

 Score =  237 bits (604), Expect = 5e-61,   Method: Compositional matrix adjust.
 Identities = 132/351 (37%), Positives = 204/351 (58%), Gaps = 5/351 (1%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFS---KPCGGLLAPDAQRSFIR 60
           +DV IIG GPAGS+LAR +  K +V+ +DK+        +   K CGGLLAPDAQ+   +
Sbjct: 2   YDVLIIGAGPAGSSLARLIGDKYKVLLIDKRDLANENPHNLAGKCCGGLLAPDAQKMIAK 61

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD 120
            GL +P D++ NPQ+F+V+T+D+  +L R YQR Y+N++R  FD W+ S++P  V+   +
Sbjct: 62  LGLGIPKDILVNPQLFAVRTIDLTNNLERLYQRFYLNMDREKFDRWLVSILPKKVDKKFN 121

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPD-HQIRKYVAIQQ 179
           ++ +        + V +  +G E     R ++GADGA S +RR L  D +   KY+AIQ+
Sbjct: 122 AVFKDFVEIPGGYEVKYIHNGQEISAKTRVIIGADGAFSKLRRFLNQDINGPEKYIAIQE 181

Query: 180 WFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAY-PMKDGQTRFTTLKEKMSAFQ 238
           W+   H VP+++ IFD  I++ YSW I K+ Y + G A  P +  + ++  LK K++   
Sbjct: 182 WYECPHHVPYFTAIFDEEISDFYSWIIPKENYLLLGSALKPKEKAREKYELLKTKLTQRG 241

Query: 239 FQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRS 298
           F F   +++E   +  P +   F  G+D+  L+GEAAG IS SS EGISYAL S+  L  
Sbjct: 242 FNFDNKIRTEGAYLYRPKKVSQFYAGRDSIALVGEAAGGISPSSAEGISYALKSSAYLAQ 301

Query: 299 VLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAHI 349
            L +  +     Y    + ++L L  K +KS  +  P LR+  M+SG+  I
Sbjct: 302 SLEEGIDGFLDRYKLKVKGIKLNLLLKNLKSPAMYNPLLRQLAMKSGLQSI 352


>UniRef50_C6JQS4 FAD dependent oxidoreductase n=1 Tax=Fusobacterium varium ATCC
           27725 RepID=C6JQS4_FUSVA
          Length = 355

 Score =  190 bits (482), Expect = 7e-47,   Method: Compositional matrix adjust.
 Identities = 115/348 (33%), Positives = 191/348 (54%), Gaps = 8/348 (2%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKK-HQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +D+ +IG GPAGS  ++ +  K +V+ LD++ ++       K CGGLLA +AQ +    G
Sbjct: 3   YDIVVIGGGPAGSVFSKFINSKYKVLLLDRRDYEDENNKIIKCCGGLLAHEAQAALSGLG 62

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSL 122
            +L  D++ +PQ+F+V+ +D   +L + Y ++Y+N +R  FD ++ S   + VE+   +L
Sbjct: 63  YSLSKDILVSPQVFNVQVIDYDNNLKKKYYKNYLNFDREKFDNYLLSQKASHVELIKGAL 122

Query: 123 CRKIWREDDK--WHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW 180
               + ED+   + VI+R     + +  + +V A+GANS++R++L  +     Y+AIQ+ 
Sbjct: 123 FID-YSEDENGIYTVIYRIGMDIKKVKTKMIVSAEGANSLIRKNL-DNKSKNDYIAIQRV 180

Query: 181 FAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQ-TRFTTLKEKMSAFQF 239
           +  K    ++  IFD +I N YSW + K    I G       G   +F  L+E++ +   
Sbjct: 181 YKMKKDFSYHMAIFDKNINNYYSWLVPKGNELILGTILKKGKGSWDKFHQLEERVKSEGI 240

Query: 240 QFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSV 299
                ++ E   +  P +W ++   KD   LIGEAAG ISASS EGISYAL S   L   
Sbjct: 241 DINDIIRDEGTFIRVP-KWNEYFMAKDRIALIGEAAGLISASSSEGISYALISGYYLADS 299

Query: 300 LLKQPEKLN-TAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGV 346
           + K+  K     Y + T  +R+KL  KI+K + +    +RK+I+ SGV
Sbjct: 300 INKKGIKSGIIEYCKRTESIRMKLNLKILKGKLMYNSFIRKFIIMSGV 347


>UniRef50_Q1PX22 Putative uncharacterized protein n=1 Tax=Candidatus Kuenenia
           stuttgartiensis RepID=Q1PX22_9BACT
          Length = 351

 Score = 85.5 bits (210), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 91/339 (26%), Positives = 147/339 (43%), Gaps = 36/339 (10%)

Query: 4   FDVAIIGLGPAGSALARKLAGK-MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +D  ++G GP+G+A A++L G+ ++V+ L+KK         K C G++   +Q    R  
Sbjct: 5   YDAVVVGSGPSGAAAAKRLTGEGLRVLVLEKKKLPRY----KICSGIIFKKSQEITERYF 60

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQ--------RSYININRHAFDLWMKSLIPAS 114
             +P  V   P++  +K V   + L  NY             N+ R  +D W+ S   A 
Sbjct: 61  GRIPDAVYVQPKL--LKGVRFWSDLG-NYSDWPFSKDSEGAPNVWRSEYDYWLISNSGAE 117

Query: 115 VEVYHDSLCRKIWREDDKWHVIFRADGWEQHI---TARYLVGADGANSMVRRHLYP--DH 169
           V    D    K +  +    V+   D  E  I     RYL+ A+G+ S +R  L P  + 
Sbjct: 118 V---MDCAVFKGFETEGNAVVVHYYDARENKIRQAKCRYLISAEGSVSCIRAMLSPAFER 174

Query: 170 QIRKYVAIQQWFAEKHPVP--FYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRF 227
            ++ ++A Q ++  +  +   FY    D      Y+W   KD   +FG +  ++ G    
Sbjct: 175 NVKWFIAYQNYYEGQSSLDPYFYHGFLDQKYGEVYAWFSVKDDLQVFGTS--VRKGAKIL 232

Query: 228 TTLKEKMSAFQFQFG----KTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSL 283
             L       + + G    K V+   C         +F  GK N  L+GEAAGF++A   
Sbjct: 233 PCLNAFHEMLEKEHGLALKKLVRKTSCLGNTMCASGNFYLGKGNILLVGEAAGFLNAFG- 291

Query: 284 EGISYALDSTDILRSVL---LKQPEKLNTAYWRATRKLR 319
           EGIS AL S       +   +K  E + +AY   T+K R
Sbjct: 292 EGISCALSSGLFAAEAICACIKSGEDVISAYTELTKKER 330


>UniRef50_A6QA88 Geranylgeranyl hydrogenase n=1 Tax=Sulfurovum sp. NBC37-1
           RepID=A6QA88_SULNB
          Length = 361

 Score = 82.8 bits (203), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 84/307 (27%), Positives = 133/307 (43%), Gaps = 32/307 (10%)

Query: 5   DVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           D+ IIG GPAGS LAR LA   +   L +++      F KPCGG +  DA   F  D   
Sbjct: 5   DILIIGGGPAGSTLARYLAEAGKETILVQRNF----NFRKPCGGGIRLDAFDEFDIDREL 60

Query: 65  LPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLCR 124
           +  +V +   +F  K V+V  S     Q     ++R  FD ++++    +     ++   
Sbjct: 61  IRKEVNSIALVFGTKRVEVDIS-----QMPLGIVDRVEFDTYLRNRAEDTGATLLEASFV 115

Query: 125 KIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEK 184
            +   D    V    DG  + I A YLVGADG NS VR+ +  D    +  +    +A+ 
Sbjct: 116 DVEVCDGYIIVTIEQDGVYKKIHAGYLVGADGVNSKVRKCINGD----RVPSAMTRYADL 171

Query: 185 HPVPFYSCIF---DNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQF 241
               + +C F        + Y+W            A+P  +G    T   +  +  Q  F
Sbjct: 172 AHTAYKTCEFHFGSKVAGSYYAW------------AFPHTNGSNIGTLAGDDETHIQ-HF 218

Query: 242 GKTVKSEKCTVLFPSRWQDF---VCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRS 298
            K +  ++   L   R   F   V  KD  F +G++A  +   + EGI YA+ S  +L +
Sbjct: 219 MKQLDVKEKVKLLGYRIPQFENPVFYKDRVFFVGDSASQVLPFTYEGIYYAMASAHLLSA 278

Query: 299 VLLKQPE 305
           VL +Q +
Sbjct: 279 VLTEQAD 285


>UniRef50_B5YGK5 Geranylgeranyl hydrogenase, putative n=1 Tax=Thermodesulfovibrio
           yellowstonii DSM 11347 RepID=B5YGK5_THEYD
          Length = 378

 Score = 71.2 bits (173), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 81/327 (24%), Positives = 135/327 (41%), Gaps = 46/327 (14%)

Query: 5   DVAIIGLGPAGSALARKLAGK-MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSF-IRDG 62
           +V ++G GPAGS  AR LA K ++ + ++K        F+KPCGG +     + F I + 
Sbjct: 4   EVLVVGGGPAGSTAARLLAEKGIETVLIEKDLT-----FNKPCGGGIPSAGLKEFNILNK 58

Query: 63  LT--LPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPAS-VEVYH 119
           L   +P +++   +IF   +  +  SL        +  NR +FD +M+ L   S V++  
Sbjct: 59  LQNQIPFNIVTKVKIFPPFSEPIEVSLQGG---EILIFNRQSFDSFMRKLAEKSGVKIIE 115

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMV---RRHLYPD-------H 169
             L   I  E+ K  V  +  G    I ++Y++ ADG NS V   +    P+       H
Sbjct: 116 AEL---INIENSKLTVR-KKTGEVLEIYSKYIIAADGVNSRVCSIKGWSKPEYYWTVSLH 171

Query: 170 QIRKYVAIQQ----WFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQT 225
            +  ++  +     WF   H   FYS +F              D + +  GA  +K  +T
Sbjct: 172 VLENFIDTKDTCEFWFGNSHASFFYSWVFPGV-----------DYFSVGTGAEDIKKLKT 220

Query: 226 RFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEG 285
                 EK    +F     + S K       +W      K+N    G+  G +   S EG
Sbjct: 221 LIDNFVEK----RFAGKLNINSFKLRAYKIPKWGRRSFFKENVIFCGDTLGTVMPISFEG 276

Query: 286 ISYALDSTDILRSVLLKQPEKLNTAYW 312
           I Y++ S       ++++   L    W
Sbjct: 277 IYYSMKSAQFASEAIVQKDLNLYKKLW 303


>UniRef50_B9M019 FAD dependent oxidoreductase n=1 Tax=Geobacter sp. FRC-32
           RepID=B9M019_GEOSF
          Length = 353

 Score = 69.7 bits (169), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 90/326 (27%), Positives = 129/326 (39%), Gaps = 52/326 (15%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGK-MQVIALDK----KHQCGTEGFSKPCGGLLAPDAQ 55
           M+ +DV I G GPAGS  A+ L  +   V+ L+K    +H        K C G+L    Q
Sbjct: 1   MQQYDVVIAGSGPAGSTCAKALKDEGFSVLVLEKEILPRH--------KTCSGVLFGQTQ 52

Query: 56  RSFIRD--GLTLPVDVIANPQIFSVKTV----DVAASL---------TRNYQRSYININR 100
              IR   G  +P +V    +      +    D    +          R + R+Y NI R
Sbjct: 53  -ELIRAYFGTHVPAEVYCGNKFVEADDIREWDDEQGYIPYTWEIDKDGRKFSRTYHNIWR 111

Query: 101 HAFDLWMKSLIPASVEVYHDSLCRKIWREDDKW---HVIFRADGWEQHITARYLVGADGA 157
             FD W   L+  S   Y D    K +         HV              Y VGADG 
Sbjct: 112 DKFDKW---LLDQSGAEYRDGAKVKAFDAGGSTVDVHVHMSRTNESAVFKCEYFVGADGN 168

Query: 158 NSMVRRHLY---PDH-QIRKYVAIQQWFAEKHPVPF----YSCIFDNSITNCYSWSISKD 209
           +S VRR L+   P++ Q  K  + Q ++  K         ++      I +       KD
Sbjct: 169 DSTVRRLLHAQNPEYAQRHKLASYQSYYKVKSLGSLKPNGWTVFLRQEIGDYILCVHQKD 228

Query: 210 GYFIFG-GAYPMKDGQTRFTTLKEKMSA-FQFQFGKTVKSEKCTV-LFPSRWQDFVCGKD 266
            Y +   G    ++ +      KE +S  F   FG+  + E CT  L P        G++
Sbjct: 229 EYLVMHVGGMDGRNLRQSMEKFKELLSGRFGVSFGEHWRDEGCTCELLP-----IFLGQE 283

Query: 267 NAFLIGEAAGFISASSLEGISYALDS 292
              + GEAAGFI   + EGIS A+DS
Sbjct: 284 KVLVTGEAAGFIYL-NCEGISAAMDS 308


>UniRef50_B9L6H5 Geranylgeranyl hydrogenase n=2 Tax=Nautiliaceae RepID=B9L6H5_NAUPA
          Length = 324

 Score = 69.3 bits (168), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 83/347 (23%), Positives = 137/347 (39%), Gaps = 50/347 (14%)

Query: 6   VAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTL 65
           + IIG GPAGS  ARKLA    V  +  K       F KPCGG +   A + F      +
Sbjct: 3   IVIIGGGPAGSTAARKLAPFYHVTLIQDKLD-----FDKPCGGGIKTKAFKEF-----DI 52

Query: 66  PVDVIANPQ---IFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIP-ASVEVYHDS 121
           P  +I +     I   K   V   L     ++   + R  FD  ++ L   A  ++ +  
Sbjct: 53  PNKLIKHSLDHVIMKYKNTTVKVDLN---GKNLSIVKRDEFDKKLRDLAQQAGAKIIYGR 109

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWF 181
                ++       I + D    ++    L+ ADG NS VR+ L     + K  A    +
Sbjct: 110 -----FKTVKNNKAIIKTDNSILNLDYDILIAADGVNSTVRKAL----NLPKIPATITHY 160

Query: 182 AEKHPVPFYSC--IFDNSIT-NCYSWSISKDGYFIFGGAYPMK-DGQTRFTTLKEKMSAF 237
           A        +C   FD  I    Y+W+   +     G       +   R+  +K K   +
Sbjct: 161 ARIDQYKVQTCEFFFDFDIGGEYYAWAFPHENLTHIGTVSRGNFENLCRYLNVKAKPKGY 220

Query: 238 QFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILR 297
           +                P+  ++ +  K+N + +G+AAG +   S EGI YA+ S D+L 
Sbjct: 221 KI---------------PTWQENIIIQKNNVYFVGDAAGQVMPLSFEGIYYAIKSADLLA 265

Query: 298 SVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRS 344
           + +L+     N  Y     K   K F  + K   L    +R +++++
Sbjct: 266 NCILE-----NKNYPNEWNKRFFKEFSLMKKLEALNKTFIRGFVVKA 307


>UniRef50_P26172 Geranylgeranyl diphosphate reductase n=34 Tax=Bacteria
           RepID=BCHP_RHOCA
          Length = 391

 Score = 68.2 bits (165), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 79/298 (26%), Positives = 125/298 (41%), Gaps = 29/298 (9%)

Query: 4   FDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSF-IRD 61
           +D  ++G GPAGS  A  +A   ++V  LD+       G  KPCGG + P   R F I D
Sbjct: 3   YDAFVVGGGPAGSTAAWDMARAGLKVALLDRA------GRIKPCGGAIPPRLIRDFDIPD 56

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYIN-INRHAFDLWMKSLIPASVEVYHD 120
            L +     A     + + VD+        +  ++  ++R  +D W++     +      
Sbjct: 57  HLLVAKITSARMISPTGRFVDIP------IENGFVGMVDREDYDEWLRERAGKAGAERLT 110

Query: 121 SLCRKIWREDDKWHVIFR--ADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQ 178
               +I R+  K  V++R    G E     R ++GADGANS VR  + P  +I    A  
Sbjct: 111 GTWLRIERDSGKTVVVWRDKVTGEEMKAETRVVIGADGANSQVRNEV-PATKIPLVFAYH 169

Query: 179 QWFAEKHPVPFY-----SCIFDNSIT-NCYSWSISKDGYFIFGGAYPMKDGQTR-FTTLK 231
           +       V  Y        +D  I+ + Y W          G    + D   +  TTL 
Sbjct: 170 EIIKAPTTVANYDPTRCDVYYDGRISPDFYGWVFPHGKTASIGMGTELPDVSLKDCTTLL 229

Query: 232 EKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYA 289
            +MS    +  +T++ E   +  P +  D      +  L G+AAG ++ SS EGI YA
Sbjct: 230 RQMSGLDKE--ETIRKEGAPI--PLQPLDVWDNGKDVVLSGDAAGVVAPSSGEGIYYA 283


>UniRef50_B5W6L5 Geranylgeranyl reductase n=2 Tax=Arthrospira RepID=B5W6L5_SPIMA
          Length = 378

 Score = 62.8 bits (151), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 87/319 (27%), Positives = 129/319 (40%), Gaps = 40/319 (12%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           FD  I+G GPAG+  A  LA K   I +  K         KPCGG ++P  Q  F     
Sbjct: 3   FDCIIVGSGPAGATAAYHLAKKGHSILVIDKAILPR---YKPCGGGVSPIVQDWF----- 54

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQ-RSYININ------RHAFDLW-MKSLIPASV 115
               D   +P I S+KTV V  +  ++      + IN      R  FD + +K  I    
Sbjct: 55  ----DFDFSPAI-SLKTVMVYYTWNKSEPIEVELKINPIWMVRREVFDYFILKQAISKGA 109

Query: 116 EVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYV 175
            V  ++    I  + D+W V    D +    T RYL+GADGA   + + L    Q +K V
Sbjct: 110 TVRDNTEVLGIEFQSDRWLVKTPEDTY----TGRYLIGADGAKGPLAKWLGFTKQ-KKLV 164

Query: 176 --AIQQWFAEKHPVPFYSCIFDNSITNCYSWSISK-DGYFIFGGAYPMKDGQTRFTTLKE 232
             A++       PV   +      + + Y W+  K DGY +  GA+  +     F  + E
Sbjct: 165 AGALELEIPTSKPVDMKTYFEFGLVNSGYGWNFPKADGYSLGAGAFSKQRKAQNFKRILE 224

Query: 233 KMSA-FQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALD 291
             +  F        +      L+  + +       NA L GEAA  +   + EGI  ++ 
Sbjct: 225 DYATFFNLNLDNATECGHPISLWDGQQK---LHTQNAVLAGEAACVVDPFTAEGIRPSIF 281

Query: 292 STDILRSVLLKQPEKLNTA 310
           S        LK  E +N A
Sbjct: 282 SG-------LKAAEAINQA 293


>UniRef50_Q1IMS5 Geranylgeranyl reductase n=1 Tax=Candidatus Koribacter versatilis
           Ellin345 RepID=Q1IMS5_ACIBL
          Length = 379

 Score = 62.4 bits (150), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 86/367 (23%), Positives = 136/367 (37%), Gaps = 47/367 (12%)

Query: 1   MEHFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M H    I+G GP+G+A A  LA     V+ LD+          KPCGG L     ++ +
Sbjct: 1   MGHQSFIIVGAGPSGTAAAYDLAKAGHSVLLLDRSEFPRV----KPCGGGLTVKTLKA-L 55

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYH 119
           R  +T PV  I    +     +     L   +   ++ +     D  ++  + A      
Sbjct: 56  RYSVT-PVVRIVAKGLQVTNNLAEPIELRGKHPICFMTVRAEFDDFCLRQTLEAGARFQK 114

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQ 179
            S    +    D  HV+ R    E H  A YL+GADGANS          ++R  +  Q 
Sbjct: 115 ISEITGVEEFPD--HVVLRTRDGEFH--AEYLLGADGANS----------KVRLLLGAQP 160

Query: 180 WFAEKHPVPFYSCIFDNS---------ITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTL 230
           WF     V  ++ +  N+         +   Y+WS  K  +   G    +         L
Sbjct: 161 WFRRAIAVEAHAPVHKNAKAMEIDFGVVPRGYAWSFHKGDHLNVG----LCTESAEVVKL 216

Query: 231 KEKMSA--FQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISY 288
              + A   + +FG    S             +       FL+G+AAG     S EGI  
Sbjct: 217 SRDLLANYLKRKFGSDEYSHFVGHYLGIGGMRYEPKHKRIFLVGDAAGMTDPLSGEGIYN 276

Query: 289 ALDSTDILRSVLLKQPEKLNTAYWRATRKLR----------LKLFGKIVKS-RCLTAPAL 337
           A+ S     S LL+  E  + +Y +A   +R           K +G +      L  P +
Sbjct: 277 AIKSGQAAASALLQNSEAPHVSYAQALADVRDDLEFCERAIGKFYGHLNAGFAMLKVPGM 336

Query: 338 RKWIMRS 344
           +K I++ 
Sbjct: 337 KKSILKG 343


>UniRef50_P96800 Uncharacterized protein Mbar_A1602 n=1 Tax=Methanosarcina barkeri
           str. Fusaro RepID=Y1602_METBF
          Length = 387

 Score = 60.8 bits (146), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 87/314 (27%), Positives = 134/314 (42%), Gaps = 38/314 (12%)

Query: 1   MEHFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M+ +DV IIG GPAGS  A  LA  K+ V+ +DK     +    KPC G L   A  SF 
Sbjct: 4   MKKYDVVIIGAGPAGSYAAYMLAKSKINVLVIDKY----SFPRYKPCAGGLTAKAFNSF- 58

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYH 119
              ++  V    N  + S K   +  +++ N     + I R  FD ++      S   + 
Sbjct: 59  DFPISKEVKYSTNSIVTSYKN-QIFHNISGNKTLVKM-IERKEFDDFLIKKAVDSGATFL 116

Query: 120 DSL-CRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHL-YPDHQIRKYVAI 177
           D +   +I  E+ ++ +  + D   +     YL+GADG N +V R     +  +  +   
Sbjct: 117 DGMKVTEITWENAEFSI--KTD--SEFFRCNYLIGADGTNGIVNRTFNIVERDLYGFAVE 172

Query: 178 QQWFAEKHPVPFYSCIFD-NSITNCYSWSISKDGYFIFGGAYP----MKDGQTRFTTLKE 232
                 +  +  ++  FD  ++ N Y W   KD Y +  GAY     MK+ Q       E
Sbjct: 173 INCPVSRDNIGKFNMTFDFGTVPNGYLWIFPKDEY-VCVGAYTTNRKMKNIQKYLLDYIE 231

Query: 233 KMSAFQFQFGKTVKSEKCTV-LFP-----SRWQDFVCGKDNAFLIGEAAGFISASSLEGI 286
           K+       G   +SEK    + P      +  DF C      L+G+AAGF    + EGI
Sbjct: 232 KL-------GLVPESEKLKGHIIPYYGINYKQPDFPC-----VLVGDAAGFGEYWTGEGI 279

Query: 287 SYALDSTDILRSVL 300
            YA+ S  I   V+
Sbjct: 280 YYAVKSGTIAAEVI 293


>UniRef50_Q6ALA8 Related to dehydrogenases (Flavoproteins) n=1 Tax=Desulfotalea
           psychrophila RepID=Q6ALA8_DESPS
          Length = 352

 Score = 59.7 bits (143), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 87/314 (27%), Positives = 129/314 (41%), Gaps = 56/314 (17%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGK--MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSF 58
           ME FD+ IIG GPAG A A++ AGK    V+ L++  Q G     K C G          
Sbjct: 1   MEFFDIVIIGAGPAGLACAKE-AGKRGYSVLVLERNGQIG----RKVCAG--------GI 47

Query: 59  IRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYI--------NINRHAFDLWM-KS 109
             +GL   +   A  + F+ +       L   YQ   I         +NR      M + 
Sbjct: 48  TWNGLMRHMPGFATERDFAKQ------HLFSRYQSCCIEADHPIVATLNREHLGRSMAEQ 101

Query: 110 LIPASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYP-- 167
              A   +  +    +I  E  K  V  R  G +  +  +YLVGADG++S+VRR+L    
Sbjct: 102 AQEAGAVIRTEEQALQIGAE--KITVRERKTGRDYSVAFKYLVGADGSSSLVRRYLGQPV 159

Query: 168 -------DHQIRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPM 220
                  + QIR      +W    H  P       +   N Y+W           GAY  
Sbjct: 160 KHIGLGLNFQIRGRAEKMEW----HLRP-------DLFVNGYAWIFPHQNTISI-GAYAD 207

Query: 221 KDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPS-RWQDFVCGKDNA-FLIGEAAGFI 278
           +   +  T LK +   +    G  ++ E+CT  + +  ++ +  G DN  FL G+AAG  
Sbjct: 208 RSIFSP-TELKRRFLVWAKAQGYGLEQERCTAGYINYDYRGYRFGSDNNIFLTGDAAGLA 266

Query: 279 SASSLEGISYALDS 292
           S  + EGI  A+ S
Sbjct: 267 SGLTGEGIYPAIVS 280


>UniRef50_B1LSG8 Geranylgeranyl reductase n=27 Tax=Proteobacteria RepID=B1LSG8_METRJ
          Length = 408

 Score = 59.7 bits (143), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 79/299 (26%), Positives = 121/299 (40%), Gaps = 69/299 (23%)

Query: 28  VIALDKKHQCGTEGFSKPCGGLLAPDAQRSF-IRDGLTLPVDVIANPQIFSVKTVDVAAS 86
           V+ LDK       G  KPCGG + P   R F I D L +     A     S KTVD+   
Sbjct: 39  VLLLDKP------GRIKPCGGAIPPRLIRDFAIPDALLVAKIRSARMVAPSGKTVDMPVG 92

Query: 87  LTRNYQRSYIN-INRHAFDLWMKSLIPASVEVYHDSLCRKIWREDDKWHVIF----RADG 141
                   ++  ++R  FD W+++    +      +   +I R DD   ++        G
Sbjct: 93  ------EGFVGMVDREHFDPWLRARAAEAGADLRAAAFERITRPDDGPPLVHFTTGAGTG 146

Query: 142 WEQH-ITARYLVGADGANSMVRRHLYPDH----QIRKYVAIQQ----------------- 179
             +H + AR +VGADGA S V R   P H    Q+  Y  I +                 
Sbjct: 147 LARHAVRARLVVGADGACSPVGRAEVPGHARMRQVFAYHEILRVPEAGAPGAGSVEATRC 206

Query: 180 --WFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAF 237
             ++  +H   FYS IF +  T       ++ G+                 +L+  + A 
Sbjct: 207 DVYYQGRHSPDFYSWIFPHGDTLSIGTGSARKGF-----------------SLRSSIRAL 249

Query: 238 QFQFG----KTVKSEKCTV-LFP-SRWQDFVCGKDNAFLIGEAAGFISASSLEGISYAL 290
           +   G    +TV+ E   + L P  RW +   G+D   L G+AAG ++ +S EGI YA+
Sbjct: 250 RVATGLDGAETVRREGAPLPLKPLKRWDN---GRD-VLLAGDAAGVVAPASGEGIYYAM 304


>UniRef50_D1RCG6 Geranylgeranyl reductase family protein n=1 Tax=Legionella
           longbeachae D-4968 RepID=D1RCG6_LEGLO
          Length = 503

 Score = 59.3 bits (142), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 82/327 (25%), Positives = 130/327 (39%), Gaps = 29/327 (8%)

Query: 5   DVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           DV I G GP+G+  A  LA   + + L   H    +   K CG  ++P + +  +  G+T
Sbjct: 27  DVLIAGAGPSGAICAYYLAQAGKKVILIDSHSFPRD---KVCGDFVSPVSLKELMTLGIT 83

Query: 65  -LPVDVIANPQIFSVKTVDVAASLTRNYQ--RSYIN----INRHAFDLWM-KSLIPASVE 116
            LP     N    +   VD    +T N    + ++N    I R   D W+  +     V 
Sbjct: 84  DLPEFKATNMITEATVYVDGQKLITDNIPQIKDFVNYGRVIPRVLLDTWIVNAAKQQGVN 143

Query: 117 VYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLY-----PDHQI 171
           V  D      +  +    V     G ++    + LVGADG+NS V R L      P H+I
Sbjct: 144 VITDCKLVNYFVNEQDVRVECEQHGKKRRFLIKILVGADGSNSTVARILQGKKPNPKHKI 203

Query: 172 RKYVAIQQWFAEKHPVPFYSCIF--DNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTT 229
              VA++ +    + +P  + +F   N+    + +  +       G    +K      T 
Sbjct: 204 ---VAVRAYCENINCIPHQATLFFTRNTFPGYFWFFPTSSTTANVGIGMVLKTFPKNETN 260

Query: 230 LKEKMSAF--QFQFGKTVKSEKCTVLFPSRWQ------DFVCGKDNAFLIGEAAGFISAS 281
           LK  +        F KT  S+   +   + W         +  KD   L G+AAGFI+  
Sbjct: 261 LKAMLLEMIGNDPFFKTKISQGMQITKIAGWPLSCYDPSTINVKDRVLLTGDAAGFINPF 320

Query: 282 SLEGISYALDSTDILRSVLLKQPEKLN 308
           + EGI YAL S  +    ++   E  N
Sbjct: 321 TGEGIQYALQSGRLAAETIIGSFETEN 347


>UniRef50_Q649G8 Geranylgeranyl reductase n=3 Tax=environmental samples
           RepID=Q649G8_9ARCH
          Length = 385

 Score = 59.3 bits (142), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 80/343 (23%), Positives = 143/343 (41%), Gaps = 35/343 (10%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGK-MQVIALDKKHQCGTEGFS--KPCGGLLAPDAQRS 57
           M+ +DV +IG GP+G+  ++  AG  ++ +  +K      EG    K CGG ++  A   
Sbjct: 1   MQQYDVIVIGAGPSGAIASKTCAGNGLKTLLFEK------EGIPRLKLCGGAVSTSALSD 54

Query: 58  FIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKS-LIPASVE 116
                  +  D+I      +           +   R  I ++R  FD ++ S  + A V 
Sbjct: 55  L---DFGIEKDLIERECYGARVHFKTHQIEVKRKSRLAILVSRDKFDAYLVSKAVDAGVA 111

Query: 117 VYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHL---YPDHQIRK 173
           ++       I  E  +  V    +  ++   A+ ++GADG NS+V +++   Y   ++  
Sbjct: 112 LHEAEKATSIKPEQSRIVV----ETNKEKYNAKVVIGADGVNSIVSKYVRDSYKPDELGF 167

Query: 174 YVAIQQWFAEKHPVPFYSCIFD--NSITN-CYSWSISKDGYFIFG--GAYP-MKDGQTRF 227
            +A +   + +    +     D    ITN  Y W   K+ +F  G  G  P MK+ +  F
Sbjct: 168 CIAAEIPASNEEVNEYIENAIDIHYGITNFGYGWVFPKEKHFSVGLCGILPSMKNSRDIF 227

Query: 228 TTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGIS 287
               +K+      F   V S     L P+   +     D   L+G+AAGF+     EGI 
Sbjct: 228 IAFIKKLG-----FSTDVNSH--AHLIPAGGYEREVCSDRIMLVGDAAGFVDPYQGEGIK 280

Query: 288 YALDSTDIL--RSVLLKQPEKLNTAYWRATRKLRLKLFGKIVK 328
           YA  S  +   R V   + ++ + +     ++    LFG+ +K
Sbjct: 281 YAFISAKLAAERVVESYENDEFSKSALDTYKRTCYSLFGENLK 323


>UniRef50_B3QZ41 Geranylgeranyl reductase n=12 Tax=Chlorobiaceae RepID=B3QZ41_CHLT3
          Length = 383

 Score = 57.0 bits (136), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 55/213 (25%), Positives = 100/213 (46%), Gaps = 19/213 (8%)

Query: 98  INRHAFDLWMKSLIPASVEVYHDSLCRKIWREDDKWHV-IFRADGWEQHITARYLVGADG 156
           + R  FD +++    A      ++  RK+ + +  + + +  A      I A+Y++GADG
Sbjct: 89  VRRERFDRFLRERAAADGTELLEAKMRKVRKTNGVYQISVDAASKGVSEIEAKYVIGADG 148

Query: 157 ANSMVRRHL-YPDHQIRKYVAIQQWFAEKHPVPFYSCI----FDNSIT-NCYSWSISKDG 210
           ANS V   L +P ++  K +AIQ+ F     +  Y+ +    FD  ++ + Y W   K  
Sbjct: 149 ANSKVANELGFPPNEY-KAIAIQERFHYSPALERYNNLVEIWFDGEVSPDFYGWIFPKAD 207

Query: 211 YFIFGGAYPMKDGQTRFTTLKEKMSA-FQFQFGKTVKS--EKCTVLFPSRWQDFVCGKDN 267
           +   G     K G  R      K+ A F+ + G  ++   E+   L     + F   +++
Sbjct: 208 HVAIGTGTDDKHGNIR------KLQARFREKIGLDIEPYLEEAAKLPMHPRKSFT--QES 259

Query: 268 AFLIGEAAGFISASSLEGISYALDSTDILRSVL 300
           A L+G+AAG ++ S+ EGI +A+ S  +    L
Sbjct: 260 AMLVGDAAGLVTPSNGEGIFFAMRSGKMAGQTL 292


>UniRef50_B0JID7 Geranylgeranyl reductase n=8 Tax=Cyanobacteria RepID=B0JID7_MICAN
          Length = 378

 Score = 54.7 bits (130), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 76/291 (26%), Positives = 122/291 (41%), Gaps = 16/291 (5%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           FD  IIG GPAG+     LA K + I +  K +       KPCGG ++P  ++ F  D  
Sbjct: 2   FDCIIIGAGPAGATAGYHLAKKGRTILILDKAKLPR---YKPCGGGVSPAIKQWFDFD-F 57

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVYHDSL 122
           T  ++       F+ K  D AA+   N       + R  FD ++ +  I     +  +S 
Sbjct: 58  TPVIENTVTQVEFTWKQGD-AATTKLNMLEPMWMVQRDRFDDFLGQQAIAVGATIQDNSE 116

Query: 123 CRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFA 182
             +I    D W V       +   + +YL+ ADG      R L    + +   A  +   
Sbjct: 117 VTQIKFVQDHWQVTTS----QGTFSGKYLIAADGVKGNTSRWLGLPAKNQAIGATLEITN 172

Query: 183 EKHPVPFYSCIFD-NSITNCYSWSISK-DGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ 240
            +  +P     FD  S+ N Y W+  K +GY I GG +    G  +   LK+++  +  Q
Sbjct: 173 AEATIPPQKAFFDFGSLKNGYIWAFPKSNGYTISGGCF---KGSIKSEELKKQLLNYARQ 229

Query: 241 FGKTVKSEKCTVLFPSRWQ-DFVCGKDNAFLIGEAAGFISASSLEGISYAL 290
            G  ++  + +    + W  +      NA + GEAAG +     EGI  A+
Sbjct: 230 KGWNLEDYRYSEYALALWNGNKPLHAQNALITGEAAGILDPLIGEGIRPAI 280


>UniRef50_A5D4V1 Dehydrogenases n=1 Tax=Pelotomaculum thermopropionicum SI
           RepID=A5D4V1_PELTS
          Length = 386

 Score = 54.3 bits (129), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 89/328 (27%), Positives = 130/328 (39%), Gaps = 44/328 (13%)

Query: 4   FDVAIIGLGPAGSALARKLAGK-MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +DV I G GPAGS LAR+LAG  ++V+ L+K+         KPCGG +   A R      
Sbjct: 3   YDVVIAGAGPAGSTLARRLAGAGLEVLVLEKEFMP----REKPCGGGITYKAARL----- 53

Query: 63  LTLP-VDVIANPQIFSVKTVDVAASLTRNYQR--SYININRHAFDLWMKSLI-PASVEVY 118
           L  P  DVI +    +V +    + +T   +   +Y+ + R +FD  +      A   + 
Sbjct: 54  LDFPWQDVIEDTVHTAVFSYQGKSEVTVRLKTPLAYM-VTRSSFDRMLADRARQAGACLV 112

Query: 119 HDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQ 178
             +  + I  E+    V   A G   H   R  VGADG N      L   H       ++
Sbjct: 113 EGAPVKDIAVENGL--VTVAAAGETYH--GRLFVGADGVNGRSAMLLGLHHPGETGPTLE 168

Query: 179 QWFA-------EKHPVPFYSCIFDNSITNCYSWSISKDGYFIFG-GAYPMKDGQTRFTTL 230
              A       +K       C    ++   Y W   K      G GA+  K        L
Sbjct: 169 AEVACPPEVLEQKRGTIRLDC---GAVPWGYGWVFPKRDRLSTGVGAFTRK-----VKEL 220

Query: 231 KEKMSAFQFQFGKTVKSEKCTVL----FPSRWQDFVCGKDNAFLIGEAAGFISASSLEGI 286
           K+ +  F  + G  + S +   L     PS  +       +A LIG+AAG +   S EGI
Sbjct: 221 KKLLGGFLAREG--LGSARILSLRGYPIPSGGRKKRIHSRSALLIGDAAGLVDPFSGEGI 278

Query: 287 SYALDSTDILRSVLL---KQPEKLNTAY 311
            YA+ S  +    +L    QPE     Y
Sbjct: 279 YYAIKSAHLAAEAILDSRAQPEGAPGLY 306


>UniRef50_C6CUN6 Monooxygenase FAD-binding n=1 Tax=Paenibacillus sp. JDR-2
           RepID=C6CUN6_PAESJ
          Length = 395

 Score = 53.9 bits (128), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 81/347 (23%), Positives = 140/347 (40%), Gaps = 61/347 (17%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGK-MQVIALDKKHQCGTEGFS--KPCGGLLAPDAQRS 57
           M  +DV ++G GP+GSA A+ LA   ++++ LD       E F   KPCG  L P A  +
Sbjct: 1   MNSYDVIVVGAGPSGSASAKMLAASGVRILMLD------AEAFPRRKPCGESLNPGAVAA 54

Query: 58  FIR----DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININ--RHAFDLWMKSLI 111
             R      +    D  ++P I   K     ASL   Y   +  +   R   DLW+    
Sbjct: 55  LGRITGYSHVQEAFDFTSSP-IQGWKVSSGRASLEAVYPEGHYGVGCRREQVDLWLAEQA 113

Query: 112 PASVEVYHD--SLCRKIWREDDKWHVIFRA-DGWEQHITARYLVGADGANSMVRRHLYPD 168
             +  V+     + R IW  +    VI R+ +G    I A  ++G+DG  S+V R    +
Sbjct: 114 SRAGAVFEQRTKVERLIWEGERVAGVIARSPEGKPMSIRASLVIGSDGLRSVVAR----N 169

Query: 169 HQIRKYVAIQQ--WFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTR 226
            ++ +Y ++++  + A  + V          +        + +G  I  G  P+  G   
Sbjct: 170 AKVNRYGSLRKAAFTARLNGV--------RGLNGRVELFTAGEGKVI--GLAPIGAGLAN 219

Query: 227 FTTL----KEKMSAFQFQFGKTVKSEKCTVLFPSRWQD-------FVCGK---------- 265
            T +    K    A + + G  ++  +       R +D         CG           
Sbjct: 220 MTVVLGSAKAASLADKDRLGIVLREARAVPELTERLRDAEIEDGVLACGPFDRPVIPHDI 279

Query: 266 DNAFLIGEAAGFISASSLEGISYALDSTD-----ILRSVLLKQPEKL 307
               L+G+AAG+    + +GI  AL S +     I++++  + P+ L
Sbjct: 280 AGMVLLGDAAGYYDPLTGQGIYRALRSAELAAPAIVQTLQTRDPDPL 326


>UniRef50_A8M2V9 Geranylgeranyl reductase n=5 Tax=Actinomycetales RepID=A8M2V9_SALAI
          Length = 406

 Score = 53.9 bits (128), Expect = 9e-06,   Method: Compositional matrix adjust.
 Identities = 75/309 (24%), Positives = 120/309 (38%), Gaps = 20/309 (6%)

Query: 44  KPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTV-DVAASLTRNYQRSYININRHA 102
           K CG  +A  A    + D L +P  V     + +++ V     ++ R   R    + R  
Sbjct: 68  KACGDGIA--AHALDVLDELGVPDPVAGYAPVSTLRLVAPSGGAVARALPRQAYTVPRTV 125

Query: 103 FDLWMKSLIPASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVR 162
           FD  + +   A+         R++    D+  V+      +  ITAR +VGADGA S+VR
Sbjct: 126 FDARLVAAAVAAGARLRRHAVRQVEVRADR--VVL-----DGRITARAVVGADGAGSVVR 178

Query: 163 RHL----YPDHQIRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSIS-KDGYFIFGGA 217
           R L     PD  +   +AI+ +       P    +   +    Y+WS    DG    G  
Sbjct: 179 RALGHRPNPDRHL--ALAIRGYAPAPSGRPEQLIVTSATRWPAYAWSFPIGDGRANVGYG 236

Query: 218 YPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGF 277
             ++        L E++ A          +       P      V G+  A L G+A   
Sbjct: 237 EVLRGESLTRGHLLERLGALLPGVDPAAVTALRAHHLPLSTHRPVPGRGRAVLAGDALSL 296

Query: 278 ISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPAL 337
           I+  + EGI YAL S  +  +   + PE     Y  A   LR +L G +  S      A 
Sbjct: 297 INPFTGEGIFYALLSGTLAGAAASRAPEHAARRYAEA---LRRRLGGHLRHSSAAAWLAR 353

Query: 338 RKWIMRSGV 346
           R+ ++ + V
Sbjct: 354 RRSVVDAAV 362


>UniRef50_Q9R5Z2 SSB16=(GAL4(1-147))-SSB16 transcriptional repressor component n=1
          Tax=Escherichia coli RepID=Q9R5Z2_ECOLX
          Length = 92

 Score = 53.5 bits (127), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 22/25 (88%), Positives = 23/25 (92%)

Query: 29 IALDKKHQCGTEGFSKPCGGLLAPD 53
          IALDKKHQCGTEGFSKPCGG  AP+
Sbjct: 3  IALDKKHQCGTEGFSKPCGGRRAPE 27


>UniRef50_A3V9M1 Geranylgeranyl reductase n=1 Tax=Rhodobacterales bacterium HTCC2654
           RepID=A3V9M1_9RHOB
          Length = 394

 Score = 53.5 bits (127), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 83/316 (26%), Positives = 129/316 (40%), Gaps = 58/316 (18%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKP--CGGLLAPDAQRSFI 59
           + FDV +IG GPAGS+ A++       +AL  +       F +P  CG L++P   ++  
Sbjct: 4   QDFDVVVIGAGPAGSSAAKRARDLGLSVALIDRAV-----FPRPKLCGALISPRGNKAVK 58

Query: 60  RDGLTLPVDVIANPQIFSV-------------KTVDVAASLTRNYQRSYININRHAFDLW 106
           R       D+  +P+++ V                D    LT  Y        R  FD W
Sbjct: 59  R-----VFDMEMSPEMYLVSRQVAFKWDGEELNRFDAPYDLTYTY--------RLDFDHW 105

Query: 107 MKSLIPASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHL- 165
           ++    A      D    ++    D  +++  +DG  + I  + L+GADGA S V +H+ 
Sbjct: 106 LQQA--AVAAGAVDMQGTRVETIHDADNLLELSDG--RRIGYKVLIGADGAASPVAKHIL 161

Query: 166 ---YPDHQIRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFG-GAYPMK 221
              Y   +I  +    +      P    S  FD  +   Y W+  K G    G GA    
Sbjct: 162 GAAYDPDKI-GFAFETEAPGGCDPEALMSIDFD-IVHWGYGWNFPKAGSRTIGLGAIRSV 219

Query: 222 DGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVL---FPSRWQDF--VCGKDNAFLIGEAAG 276
           D       LK +M+ +    G  V  +  T+     P    DF    GK N  L G+AAG
Sbjct: 220 D-----QDLKARMARYLAHEG--VDPDSVTIKGAHIP--LGDFKEKPGKGNVLLAGDAAG 270

Query: 277 FISASSLEGISYALDS 292
           F+   + EGI+ A++S
Sbjct: 271 FVDGITGEGIALAIES 286


>UniRef50_UPI0000D53425 oxidoreductase n=1 Tax=Psychroflexus torquis ATCC 700755
           RepID=UPI0000D53425
          Length = 310

 Score = 53.5 bits (127), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 80/324 (24%), Positives = 133/324 (41%), Gaps = 49/324 (15%)

Query: 4   FDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLL-APDAQRSFIRD 61
           +DV +IG GPAGS +AR  A G ++V+ +D +   GT      CG L+   D  R    D
Sbjct: 7   YDVIVIGGGPAGSTVARYAAEGGIRVLVMDARKSIGT---PLQCGELVPTNDEMRRLCPD 63

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTR-----NYQRSYININRHAFDLWMKSLIPASVE 116
              +  D+   P     +  D    +T      +Y+   + +NR   D   ++L+  + E
Sbjct: 64  VPDMD-DLFQTPDEAISRKCDTMNIITPSGKSLSYRFEGLILNRVTHD---EALVSLAKE 119

Query: 117 VYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYV- 175
              + L     +E ++  V  R DG  +  TA+ +VGA G    VRR  + +  +   V 
Sbjct: 120 AGAEYLVNSFVKEVNENTVTTR-DG--ETYTAKVIVGAGGHKDPVRRKYWREKTVNIPVK 176

Query: 176 ----------AIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQT 225
                     A++  F    P   Y+ +F  S+       I K+    F     +K+  T
Sbjct: 177 FELKDGDYGEAVELHFGSMAP-GGYAWMFPKSVGANIGLGIQKN----FAKGKSLKEYST 231

Query: 226 RFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEG 285
            F    E  S F+            ++      + FV  K+N  L+G++AG +  S+  G
Sbjct: 232 AFIDKYEGESTFK---------GGGSLPMSGTIKRFV--KENYVLVGDSAGMVLPSNGAG 280

Query: 286 ISYAL-----DSTDILRSVLLKQP 304
           I+ A+         I R +L  +P
Sbjct: 281 ITIAMVGGRIAGQAIARHILEGEP 304


>UniRef50_Q2NER9 Digeranylgeranylglycerophospholipid reductase 3 n=2
           Tax=Methanosphaera stadtmanae DSM 3091 RepID=GGR3_METST
          Length = 397

 Score = 52.4 bits (124), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 77/317 (24%), Positives = 130/317 (41%), Gaps = 22/317 (6%)

Query: 1   MEHFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCG-GLLAPDAQRSF 58
           ++  DV IIG GPAGS  AR+ +    + + +DKK + GT    K C  G+++   +R  
Sbjct: 3   IKEVDVLIIGAGPAGSLAAREASKNGAKTLIIDKKSEIGT---PKRCAEGIMSGVLERVH 59

Query: 59  IRDGLTLPVDVIANPQIFSVKTVDV-AASLTRNYQRSYININRHAFDLWMK-SLIPASVE 116
           I          I   +I S           T     + I + R  FD  M    I    E
Sbjct: 60  ITPDERWIARKIDGARIVSPNNTSAWFTPETLETPATGIILERKVFDKHMTMDAIREGAE 119

Query: 117 VYHDSLCRKIWREDDKWHVIFRADGWE-QHITARYLVGADGANSMVRRHLYPDHQIRKYV 175
           V   +    + RE D + V  ++   E   I A  ++GADG    V R      ++   V
Sbjct: 120 VMIKTEALSMKREGDGYLVDIKSFNKEYNQIKAHIVIGADGPEGHVARW----AELNTKV 175

Query: 176 AIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGY-FIFGGAYPMKDGQTRFTTLKEKM 234
            + +  +          + +NS+   +  S++  GY +IF   Y   +     + +K + 
Sbjct: 176 PLAEMESGLQYEMTNLKMKNNSVIQFFFGSVAPGGYAWIFPKGYDTANVGIDISGIKAEK 235

Query: 235 SAFQFQ---FGKTVKSEKCTVLFPSRWQDFVCG------KDNAFLIGEAAGFISASSLEG 285
           SA ++         +++   ++  +   + +CG       DN  L+G+AAG +S  +  G
Sbjct: 236 SAVKYLNDFIANCDETKDGQIVEINAGGNPLCGIFDKIITDNVMLVGDAAGCVSPITGGG 295

Query: 286 ISYALDSTDILRSVLLK 302
           I  AL+S  I   V  K
Sbjct: 296 IDTALESGMIAGRVAAK 312


>UniRef50_A0B5F9 Geranylgeranyl reductase n=1 Tax=Methanosaeta thermophila PT
           RepID=A0B5F9_METTP
          Length = 368

 Score = 52.4 bits (124), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 65/261 (24%), Positives = 109/261 (41%), Gaps = 27/261 (10%)

Query: 44  KPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTV--DVAASLTRNYQRSYININRH 101
           KPCGG L+  A RS++R    +P +VI + ++  ++    D  A ++R  + S + + R 
Sbjct: 39  KPCGGALSEKA-RSYLR--FRIPDEVI-DAEVSRIRIFFRDRCAEISRPERLSTL-VTRS 93

Query: 102 AFD-LWMKSLIPASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSM 160
            FD + ++    A  EV        I  ED    ++       +    R LV ADG   M
Sbjct: 94  VFDDILVRRAADAGAEVLFGKKATGISEEDGCVRIM-----AGESYKGRLLVLADGHTGM 148

Query: 161 VRRHLYPDHQIRKYVAIQQWFAEKHPVPFYSC--IFDNSITNCYSWSISKDGYFIFGGAY 218
           + R + P   +R    + +  AE+       C  I    +   Y+W +   G ++  GA 
Sbjct: 149 LSRKICPGDGMRGVCLVSEVAAEETN----DCMEIHFGEVDRGYAW-VFPHGSYLSVGAG 203

Query: 219 PMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFI 278
            +     R   +   M A  F+    +      +  PSR+     G     L G++AG +
Sbjct: 204 GLGSSNIR-VIMDRLMRARGFR--GRIHGHTIPLSGPSRY----LGGRRTMLCGDSAGMV 256

Query: 279 SASSLEGISYALDSTDILRSV 299
              + EGI+YA+ S  I   V
Sbjct: 257 DPFTGEGIAYAVRSGQIAAQV 277


>UniRef50_B3ECC8 Geranylgeranyl reductase n=3 Tax=Chlorobium RepID=B3ECC8_CHLL2
          Length = 389

 Score = 52.0 bits (123), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 83/307 (27%), Positives = 122/307 (39%), Gaps = 49/307 (15%)

Query: 8   IIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLP 66
           ++G GP+GS+ A   A   M V  +DK          K CGGLL    ++ F+    T  
Sbjct: 9   VVGAGPSGSSAAYTFAKNGMDVCVIDK----AIFPRDKLCGGLLTRRTKQCFLDVFGTGW 64

Query: 67  VDVI---ANPQIFSVKTVDVAASLTRNYQRSYININRHAFD--LWMKSLIPASVEVYHDS 121
            D+    +N  +F  K   + A    NY   +   NR  FD  L  K +   +  V  D 
Sbjct: 65  EDIHECWSNGALFFHKGQMINA--IENYGELFF-CNRRTFDHALLEKVMAKGADVVLGD- 120

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWF 181
              ++   D    +     G E  I  RYL+GADG NS+V R +      R   A    F
Sbjct: 121 ---RVEGVDTTLKMCRLRSGRE--IRYRYLIGADGVNSVVARAVTSKGFDRNRYA----F 171

Query: 182 AEKHPVPFYSC---------IFDNSITNCYSWSISKDGYFIFG-GAYPMKDGQTRFTTLK 231
           A +   P   C         I+   +   Y W   K   +  G GA   K+G        
Sbjct: 172 AVQAETPDVICRQNDMILPEIYFGEVDWGYGWVFPKKNSYSVGIGALCQKNGDV------ 225

Query: 232 EKMSAFQF-QFGKTVKSEKCTVLFPSRWQDFVCGKDNA-----FLIGEAAGFISASSLEG 285
               A +F +F     S+ C+V     +  F     NA      ++G+AAG +   + EG
Sbjct: 226 ----AGKFREFYLARNSQPCSVTLKGHYIPFGNFSRNAVAKDIVIVGDAAGLVDPITGEG 281

Query: 286 ISYALDS 292
           I+YA++S
Sbjct: 282 IAYAIES 288


>UniRef50_Q2S264 FAD dependent oxidoreductase, putative n=1 Tax=Salinibacter ruber
           DSM 13855 RepID=Q2S264_SALRD
          Length = 385

 Score = 51.2 bits (121), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 101/389 (25%), Positives = 157/389 (40%), Gaps = 68/389 (17%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           +D  +IG G +G + A +LA +   + L ++    T    K CG  L+P+AQ SF R G+
Sbjct: 3   YDALVIGGGLSGCSTALQLAREGHDVLLAEQS---TYPRQKLCGEFLSPEAQSSFRRLGV 59

Query: 64  TLPVDVI-ANPQIFSVKTVDVAASLTRNYQRSYININRHAFD-LWMKSLIPASVEVYHDS 121
              V    A P   +  T    A+ + +   + +  +R+  D L  +      VE    +
Sbjct: 60  LDDVRAAGAEPIGRTCLTTSSGATTSHSLPDAALGFSRYRLDQLLFQKACTMGVEGRSGT 119

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPD--HQIRKYVAIQQ 179
               I          F A      + AR ++GA G  S + R L      +   YVA + 
Sbjct: 120 RVTNI---RGGLRDGFVASVGGDSVEARLVLGAHGRRSRLDRSLERPFLSENTPYVAFKA 176

Query: 180 WFA-----------EKHPVPFYSC----IFDNSITNCYSWSISKDGYFIFGGAYPMKDGQ 224
            +A           E H  P   C    +  N I  C  W    D     GG+    +G 
Sbjct: 177 HYAGPTAAALENTIELHSAPGAYCGLSPVEGNRINVC--WIGRTDALKDAGGS---PEGM 231

Query: 225 TRFTTLKEKMSAFQFQFGKTVKSEKCTV-----LFP-SRWQDFVCGKDNAFLIGEAAGFI 278
              TTL++  +  +   G T  S++        L P SR+ D VC      +IG+AAG I
Sbjct: 232 LN-TTLRQNPAFDERLSGLTRVSDRFEAVSQVPLMPKSRFADDVC------MIGDAAGMI 284

Query: 279 SASSLEGISYALDSTDI---LRSVLL--KQP-EKLNTAY---WRATRKLRLKLFGK---- 325
           +    +G++ AL + D+   L S  L  + P     T+Y   W  T   R++L G+    
Sbjct: 285 APLCGDGMAMALRTADLVSPLASDFLNGRHPAHAFRTSYETAWTDTFGQRMRL-GRWIHA 343

Query: 326 ----------IVKSRCLTAPALRKWIMRS 344
                     +V+S C   P L +WI+RS
Sbjct: 344 AAFRPGAAWTLVQS-CRLLPPLAQWIIRS 371


>UniRef50_O29786 Digeranylgeranylglycerophospholipid reductase n=1 Tax=Archaeoglobus
           fulgidus RepID=GGR_ARCFU
          Length = 387

 Score = 50.1 bits (118), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 45/167 (26%), Positives = 74/167 (44%), Gaps = 15/167 (8%)

Query: 4   FDVAIIGLGPAGSALARKLAGK-MQVIALDKKHQCGT-----EGFSKPCGGLLAPDAQRS 57
           +DV ++G GPAGS  A+  A + ++V+ ++K+ + GT     EG S+          ++ 
Sbjct: 2   YDVVVVGAGPAGSMAAKTAAEQGLKVLLVEKRQEIGTPVRCAEGISRES-------IEKF 54

Query: 58  FIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIP-ASVE 116
           F  D   +  +V         KT  V +      +  Y+ + R  FD  +  L   A  E
Sbjct: 55  FEVDKKWIAAEVTGAKIYAPNKTEIVMSEEMAGNEVGYV-LERKIFDRHVARLAAKAGAE 113

Query: 117 VYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRR 163
           VY  +      R+D K  V  R  G +  +  + L+GADG  S + R
Sbjct: 114 VYVKTAMVDFERKDGKVKVKLRRLGEDWEVETKILIGADGVESKIGR 160


>UniRef50_UPI0001C42077 geranylgeranyl reductase family protein n=1 Tax=Methanobrevibacter
           ruminantium M1 RepID=UPI0001C42077
          Length = 432

 Score = 50.1 bits (118), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 67/317 (21%), Positives = 141/317 (44%), Gaps = 34/317 (10%)

Query: 4   FDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +DVAI+G GP GS+LA +LA   ++V  +DKK +    G    C G++        I   
Sbjct: 5   YDVAIVGAGPIGSSLAYELAQNGLKVCLIDKKKRI---GLPLQCAGIV-----NKRISSL 56

Query: 63  LTLPVDVIANPQIFS-VKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDS 121
             +P ++I N    + + + + + ++++   ++Y+ ++R AFD ++ +     ++ Y   
Sbjct: 57  CDIPKELILNEAKGAFIHSKNHSLTVSKKESQAYV-LDRVAFDQYLFNRAREHLDTY--- 112

Query: 122 LCRKIWREDDKWHVI-FRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW 180
           L  K+   D +  ++ F+ D   + I ++ +VGADG  S+  + +   +    Y    Q+
Sbjct: 113 LSSKVVDIDTELGIVQFKFDCEIKTIRSKIIVGADGPLSLSAKKV---NSKLNYFNASQY 169

Query: 181 FAEKHPVPFYSCIFDNSITNCYSWSISKDGYF----IFG-----GAYPMKDGQTRFTTLK 231
             +   +       + S  + Y+W     G+     ++      G +   D +++   L 
Sbjct: 170 LVKVDKID------EMSFVDLYAWGDLFPGFIWAIPVYSNIYRIGLFSEDDYKSQSKMLD 223

Query: 232 EKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALD 291
           + +   +F++ +    EK     P   +     K+   LIG+AA  +  ++  GI   L+
Sbjct: 224 DYLEN-EFRYDEYEVLEKYKGKIPIYDKSNKLFKNRLILIGDAASQVKPTTGGGILIGLE 282

Query: 292 STDILRSVLLKQPEKLN 308
           S    +  +L     L+
Sbjct: 283 SVQFAKDAILNALNTLD 299


>UniRef50_Q8TMB3 Putative uncharacterized protein n=1 Tax=Methanosarcina acetivorans
           RepID=Q8TMB3_METAC
          Length = 257

 Score = 49.7 bits (117), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 50/220 (22%), Positives = 96/220 (43%), Gaps = 15/220 (6%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGF--SKPCGGLLAPDAQRSFI 59
           + +D+ IIG GPAGS  A  LA   +V+ ++        G   +K C G+L   +     
Sbjct: 3   KQYDITIIGAGPAGSMSAYNLAKHFKVLIVE------AHGLPRNKSCSGILIKKSVDILE 56

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVY 118
           +    +P +V   P   +  T+     + R++    +NI R  FD W+ +  I A  ++ 
Sbjct: 57  KYFDNIPDNVKCTPYETNGITIIDEYMVPRDFPDKGLNILRDKFDYWLVQHAIKAGADLI 116

Query: 119 HDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQ 178
             S   K+   ++   +  ++D   + I ++ ++  DG +   R       Q  K V  Q
Sbjct: 117 DHSRVVKLDENENGVTLTIKSDSVYK-INSKIVIACDGVSGTSRIMTNTPKQ-NKLVTYQ 174

Query: 179 QWFAEKHPV---PFYSCIFDNSITNCYSWSISKDGYFIFG 215
           +++  +  +    FY+ I  N  +   SW  +K+ + + G
Sbjct: 175 KYYNARASIDRSKFYAYISKN-FSEYDSWINTKNNHIVVG 213


>UniRef50_A6CDB5 Geranylgeranyl reductase n=1 Tax=Planctomyces maris DSM 8797
           RepID=A6CDB5_9PLAN
          Length = 375

 Score = 49.7 bits (117), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 78/321 (24%), Positives = 123/321 (38%), Gaps = 45/321 (14%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGK-MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           E  DV I+G GP GS+ A  L    + V+ LD+     T    K C G + P      + 
Sbjct: 4   ESCDVLIVGGGPGGSSCAWGLQDSGLDVLILDQ----ATFPRDKVCAGWITPA-----VT 54

Query: 61  DGLTLPVD------VIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPAS 114
           D L L +       V+     F    +  AA  T   Q     I R  FD ++ S   A 
Sbjct: 55  DLLNLDLSDYQKSHVLQPITRFRTGIIGGAAVQTEFTQTVSYGIRRCEFDEYLLSRCGAR 114

Query: 115 VEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKY 174
             +      + + R ++ W V          + A+ +VGA G    V R L P+ +    
Sbjct: 115 TRLGEK--FQSLERTENGWLV-------NGSLQAKVIVGAGGHFCPVARWLNPEKRSEHS 165

Query: 175 VAI-QQWFAEKHPVPFYSC--------IFDNSITNCYSWSISKDGYFIFGGAYPMKDGQT 225
           V + Q+   +  P     C        ++ +     Y+W   KDGY   G     ++G+ 
Sbjct: 166 VVLAQETEFQLTPEQLKVCRVQPERPELYFSPDLRGYAWCFLKDGYLNVGIG---REGEK 222

Query: 226 RFTTLKEKMSAFQFQFGKTVKS------EKCTVLFPSRWQDFVCGKDNAFLIGEAAGFIS 279
           + +  +++   F    G+  +            L+    +  V   D   LIG+AAG  S
Sbjct: 223 QLSAARDEFIQFLDLEGRVPRGILGKFKGHAYRLYGLEKRSVV--DDRILLIGDAAGLAS 280

Query: 280 ASSLEGISYALDSTDILRSVL 300
             S EGI  A++S  +   VL
Sbjct: 281 PQSGEGIRPAVESGLMAADVL 301


>UniRef50_C0GUA1 Geranylgeranyl reductase n=1 Tax=Desulfonatronospira thiodismutans
           ASO3-1 RepID=C0GUA1_9DELT
          Length = 368

 Score = 49.3 bits (116), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 80/315 (25%), Positives = 132/315 (41%), Gaps = 56/315 (17%)

Query: 4   FDVAIIGLGPAGSALARKLAGK-MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +DV IIG GPAG+  A  LA K M V  LDKK    +    K C G+L    Q++  +  
Sbjct: 5   YDVIIIGCGPAGATAALLLAAKGMDVAVLDKK----SFPRFKLCAGML---TQKTLDQCS 57

Query: 63  LTLPV--------DVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFD-LWMKSLIPA 113
           L  P         D+I +       +       T + + SY+ ++R ++D LW + +   
Sbjct: 58  LFYPELAHELKKRDIIRHVSSQYAISTGKKRLYTGSSKYSYVLVDRESYDQLWHEKVRET 117

Query: 114 SVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITA--------RYLVGADGANSMVRRHL 165
              VY +               I R D  E  +TA        R+++GADG +S VR+ L
Sbjct: 118 GASVYREQ--------------IVRVDIPESRVTAKNGRVFRGRFILGADGGSSRVRKTL 163

Query: 166 YPDHQIR------KYVAIQQWFAEKHP-VPFYSCIFDNSITNCYSWSISKDGYFIFG-GA 217
             +  +R        +A++ + + +    P +  +F   + + Y+WS         G  +
Sbjct: 164 ALEKVVRPPWSKGSALALETFVSRQQAGFPDFPELFTGIVPDGYAWSFPGASRQRLGICS 223

Query: 218 YPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTV---LFPSRWQDFVCGKDNAFLIGEA 274
             +KDG+     L++ M       G+ V  ++  +   + P    +   G  N  L+G+A
Sbjct: 224 AVVKDGR----ELRKIM--LDLLAGQGVHLDEKEIRGHVLPYGDYEKTPGFQNILLLGDA 277

Query: 275 AGFISASSLEGISYA 289
           AG       EGI YA
Sbjct: 278 AGMADPLLGEGIYYA 292


>UniRef50_C3NB54 FAD dependent oxidoreductase n=12 Tax=Sulfolobaceae
           RepID=C3NB54_SULIY
          Length = 395

 Score = 48.9 bits (115), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 85/338 (25%), Positives = 137/338 (40%), Gaps = 82/338 (24%)

Query: 4   FDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           FD+ ++G GPAGS+ A   A G  +V+ L++    G E  SK   G +      S + D 
Sbjct: 3   FDIVVVGAGPAGSSAAITAARGGAKVLLLER----GPEPGSKNVSGAMIRLEDFSSVYDI 58

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININ---------RHAFDLWM-KSLIP 112
            ++P++         VK VD+   L  N  R+ I++N         R   D WM +    
Sbjct: 59  ASIPIE-------RKVKNVDLI--LLSNSNRTRISVNVESNLATVARLKLDKWMAQQAEK 109

Query: 113 ASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMV------RRHLY 166
           A   +   +    + RE +++ V    D  E  + A  +V A+G N++V      R  L 
Sbjct: 110 AGALLITKTTVLGVEREGNEYKV--ETDRGE--VRADRVVLAEGVNALVSMKANIRPDLT 165

Query: 167 PDHQIR--KYV------AIQQWFAEK-------------HPVPFYSCIFDNSITNCYSWS 205
           PDH ++  K V       + + F  K              PVP+   ++           
Sbjct: 166 PDHAVQTVKEVYSLNKDEVNKRFGFKADDEGVSWRILGIDPVPYAGFLY----------- 214

Query: 206 ISKDGYFIFGGAYPM----KDGQTRFTTL---KEKMSAFQFQFGKTVKSEKCTVL----F 254
           + KD   I G   PM    K   T +T L   KE++   +   G +++     V+    F
Sbjct: 215 VYKDAVAI-GAGIPMKILIKRKITPYTVLDEVKERLGFNELVKGASLREYSAKVIPEYGF 273

Query: 255 PSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDS 292
           PS W+   C     +L G+A G +   +  GI  A+ S
Sbjct: 274 PS-WK--AC-SGKIYLAGDAIGLVDPLTFNGIGPAVAS 307


>UniRef50_A8ME14 Geranylgeranyl reductase n=1 Tax=Caldivirga maquilingensis IC-167
           RepID=A8ME14_CALMQ
          Length = 362

 Score = 48.9 bits (115), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 51/166 (30%), Positives = 78/166 (46%), Gaps = 16/166 (9%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIAL--DKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
           +D+ IIG GPAG+A A  +A ++ V AL  DK          KPCGG L P  +   +  
Sbjct: 2   YDLIIIGSGPAGNA-AALVASRLGVRALIIDKSKHPRV----KPCGGGLTP--KTIALSR 54

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHA-FDLWM-KSLIPASVEVYH 119
            L L +  +   +   V  V  A S    ++   I ++R    D +M    +   VE  +
Sbjct: 55  ILGLDLSEVIEHECGEVLVVTHAGSFVMRFKEPMIRVSRRERLDEFMFNEAVNNGVEYVN 114

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHL 165
           D + R +     K  VI R+  +E    A++++GADGA S V R +
Sbjct: 115 DEVLR-VRETPSKVEVIGRSSVYE----AKWVIGADGAPSRVGRSI 155


>UniRef50_UPI0001C421FD hypothetical protein BpOF4_18960 n=1 Tax=Bacillus pseudofirmus OF4
           RepID=UPI0001C421FD
          Length = 438

 Score = 48.1 bits (113), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 77/323 (23%), Positives = 127/323 (39%), Gaps = 47/323 (14%)

Query: 5   DVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           +V I G G AG  LA KLA K Q+     + Q G     K  G LL P     F    ++
Sbjct: 8   EVFIAGGGVAGLTLALKLA-KHQIDVTVVEKQKGMGNVYK--GELLQPKTLSIFEELEIS 64

Query: 65  LPVDVIANP-QIFSVKTVDVAA----SLTRNYQRSYININRHAF---DLWMKSLIPASVE 116
             ++   NP Q    K VD        +  +Y R  I  N  A    +   + L+  +  
Sbjct: 65  TQINKEINPLQKIVTKEVDEKNRQLLEVVMDYSRLPIENNTAAMIPHNTLKEILLNEASR 124

Query: 117 VYHDSLCR--KIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKY 174
             H  L +     R++    V+ + +G E  I A  ++GA+G  S VR+ +  D  +++ 
Sbjct: 125 YPHFHLLQPAAFLRKEGTNEVVIKREGLESVIEANIIIGAEGRGSKVRKSV--DIPLKQS 182

Query: 175 VAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTL---- 230
               Q+     P P    + D  +   +           F G +P+ DG+ R   L    
Sbjct: 183 TYTHQFLTVTFPSP--PSLVDGEMIGNHER---------FLGLFPLPDGEVRSVLLIRGD 231

Query: 231 ------KEKMSAF-----QFQ-----FGKTVKSEK-CTVLFPSRWQDFVCGKDNAFLIGE 273
                 K+ + AF     Q +     +   +KS K   ++ P R       + N  +IG+
Sbjct: 232 EYKQMKKQGLEAFYEAYIQLKPELEGYVNQIKSWKDIQLMVPIRHTVTHYTEGNVVIIGD 291

Query: 274 AAGFISASSLEGISYALDSTDIL 296
           AA  +   + EG++ A+    +L
Sbjct: 292 AAHSVHPMAGEGMNLAIQDAYVL 314


>UniRef50_Q8DGN7 Tlr2279 protein n=5 Tax=Cyanobacteria RepID=Q8DGN7_THEEB
          Length = 375

 Score = 47.8 bits (112), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 70/299 (23%), Positives = 117/299 (39%), Gaps = 32/299 (10%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           +D  ++G GPAG + A  LA + + + + +K     +   KPC G ++P   + F  D  
Sbjct: 5   YDCIVVGSGPAGGSAAYHLARRQRSVLVLEKAALPRQ---KPCTGGISPVIGQWFDVDFQ 61

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLC 123
               D     + +S K  D   +     +  +I + R  FD ++         V  D   
Sbjct: 62  PAIADTTRTVR-YSWKFKDAVEAELSIPEPIWI-VERTVFDHYLLQQAQQKGAVVAD--- 116

Query: 124 RKIWREDDKWHVIFRADGWEQHIT-----ARYLVGADGANSMVRRHLYPDHQIRKYVAIQ 178
                + +   + F+ D W+ H        RYL+ ADGANS + R L    ++ +  A+ 
Sbjct: 117 -----QTEVTGITFQKDHWQVHTATTTYGGRYLIAADGANSQMARWLGFKPKVGRTAAV- 170

Query: 179 QWFAEKHPVPFYSCIFD-NSITNCYSWSISKDGYFIFGGAYPMKDGQTRFT-TLKEKMSA 236
                 +P    +  F+   + N Y WS  K      G A      +  +   L++  + 
Sbjct: 171 --MTVPNPRGDRAAHFEFGLVKNGYLWSFPKGDQRTVGVAVVRGSDRPNWEPILQQYCAV 228

Query: 237 FQFQFGKTVKSEKCTVLFPSR--WQ-DFVCGKDNAFLIGEAAGFISASSLEGISYALDS 292
            Q Q         C + +     W+        +A L GEAAG +   S EG+  AL S
Sbjct: 229 HQLQLA------DCPIQYHPLCIWEGQQPLHTHHALLAGEAAGLVDPFSAEGVRPALYS 281


>UniRef50_Q3A1Y0 Flavoprotein-containing dehydrogenase n=1 Tax=Pelobacter
           carbinolicus DSM 2380 RepID=Q3A1Y0_PELCD
          Length = 414

 Score = 47.0 bits (110), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 74/307 (24%), Positives = 117/307 (38%), Gaps = 25/307 (8%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGF--SKPCGGLLAPDAQRSF 58
           ++ +DV I G GPAGS  A  LA     + L  +     + F  SK CG  L P A R  
Sbjct: 25  VQTWDVIIAGAGPAGSIAAITLADMGHRVLLTDR-----DWFPRSKVCGDCLTPGAMRIL 79

Query: 59  IRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFD-LWMKSLIPASVEV 117
            R GL     + A  +   ++ +   A +  +    Y+ + R   D L  +  + A V  
Sbjct: 80  RRYGL-FDAALHAGHRCTQMR-IYSPAHVRIDVPGDYLTVKREILDQLLARKALAAGVTF 137

Query: 118 YHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAI 177
              +      R D +  V FR +G    +    L+   G  ++ ++     H +    A+
Sbjct: 138 VRGTAAALEKRGDAEIAVRFR-EGPSMQVARCGLLATGGRLALAQKSGLVAHPVASGAAV 196

Query: 178 QQWFAEKHPVPFYSCIFDNSITNCYSW--SISKDGYFIFGGAYPMKDGQTRFTTLKEKMS 235
           + +   + P+       + +I   Y+W   + KD Y +  G +  +  +     LK    
Sbjct: 197 RCYVRSRLPIKHMVIACERTILPGYAWIFPVEKDLYNVGCGRFMYRQTEPHL-HLKRSFH 255

Query: 236 AFQFQF---------GKTVKSEKCTVLFPSRWQDFVCGKDNAFL-IGEAAGFISASSLEG 285
           AF   F         G      K  VL  S WQ        A L +GE  G  S  + EG
Sbjct: 256 AFLHTFPIARELMEQGDMETPLKGAVLR-SGWQHIGPMASGACLGMGEMVGTTSPYTGEG 314

Query: 286 ISYALDS 292
           I  A+ S
Sbjct: 315 IGKAMQS 321


>UniRef50_B8GFT3 Geranylgeranyl reductase n=1 Tax=Methanosphaerula palustris E1-9c
           RepID=B8GFT3_METPE
          Length = 401

 Score = 46.6 bits (109), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 82/317 (25%), Positives = 125/317 (39%), Gaps = 55/317 (17%)

Query: 5   DVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQ----RSF- 58
           DV ++G GPAG   A  LA    QV+ +DK     T    K C G L    +    R+F 
Sbjct: 13  DVVVVGAGPAGVTAAYLLAKDGHQVLLIDK----ATFPRKKLCAGCLTEKTRDLLSRTFG 68

Query: 59  ------IRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIP 112
                 IR+G+   V   A+    S +   +     RN    +  ++R A+D  + +   
Sbjct: 69  LTETYMIREGI---VAATADHYQISCRREMIC---KRNTSIPFTFVDRTAYDAKLLAAA- 121

Query: 113 ASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRH--LYPDHQ 170
               V   + C ++   D    ++   DG  + IT RYL+GADG NS VR    + P+ +
Sbjct: 122 EEAGVTVITGC-EVTSVDPLIGLVMTRDG--RTITGRYLIGADGVNSRVRHAFPITPEDK 178

Query: 171 IRKYVAIQQWFAEKHP----VPFYSCIFDNSI--------TNCYSWSISKDGYFIFGGAY 218
            R +  +      K P     P +S I D+ I           Y W+   +   I G   
Sbjct: 179 NRWFQNLASTVEIKVPRSRLAPPFSGI-DHPILFFDLPGWKAGYGWAFPGEEEVILGIGG 237

Query: 219 PMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQ----DFVCGK--DNAFLIG 272
             + G+ R   +        F+     K  +  V  P  W     +F+       A L+G
Sbjct: 238 LKQGGERRVAEI--------FKTCLAAKGLEDMVSHPQGWALPYGNFIRNPTFGVALLVG 289

Query: 273 EAAGFISASSLEGISYA 289
           +A GF+     EGI YA
Sbjct: 290 DAGGFVEPFLGEGIFYA 306


>UniRef50_Q11W52 Probable electron transfer flavoprotein n=1 Tax=Cytophaga
           hutchinsonii ATCC 33406 RepID=Q11W52_CYTH3
          Length = 384

 Score = 46.2 bits (108), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 78/324 (24%), Positives = 132/324 (40%), Gaps = 58/324 (17%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           FDV I+G GPAGS  A  L      +AL +K     +   K CG  L+  A+R   +   
Sbjct: 9   FDVIILGAGPAGSTAALALQKSNLTVALLEKELFPRD---KICGDALSCVAERVLKQIDP 65

Query: 64  TLPVDVIANPQIFSVKTVDVAA--------SLTRNYQRSYININRHAFDLWMKSLIPA-S 114
           +L  +++    ++S KTV   A        S+  N+ +    I R  FD W+     A +
Sbjct: 66  SLEQELL----LYSEKTVVNKARVYSPEFRSIVLNFSKRGHCIKRLDFDNWLFEKANAKN 121

Query: 115 VEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKY 174
           +EV+  +    +  ++    V+ + DG   H  A  ++  DGA+S+  R L      RK+
Sbjct: 122 IEVFQQAKVTDVRIDNSGAEVVLQ-DGTILH--AAIVICCDGAHSVAARQLTHLKLDRKH 178

Query: 175 V--AIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKD---GYFIFGGAYPMKDGQTR--F 227
              A++Q++              ++  N       KD   GYF     +P+K+G+    F
Sbjct: 179 YVGAVRQYYRN----------ISDTAGNELEIFFLKDFLPGYFWI---FPLKNGEANVGF 225

Query: 228 TTLKEKMSAFQFQFGKTVKSEKCTV-LFPSRWQD------------------FVCGKDNA 268
             L   +S  +    K+++    +V     R++D                        + 
Sbjct: 226 GALSAIISKNKIDLKKSLQEIIQSVPQLKERFKDAEAMETVKGFGLPLGSRKLPISGAHF 285

Query: 269 FLIGEAAGFISASSLEGISYALDS 292
            L G+AA  I   + EGI  A++S
Sbjct: 286 MLCGDAASLIDPVTGEGIETAMES 309


>UniRef50_A6GD06 Geranylgeranyl reductase n=1 Tax=Plesiocystis pacifica SIR-1
           RepID=A6GD06_9DELT
          Length = 407

 Score = 45.8 bits (107), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 45/164 (27%), Positives = 69/164 (42%), Gaps = 16/164 (9%)

Query: 140 DGW-----EQHITARYLVGADGANSMVRRHL--YPDHQIRK--YVAIQQWFAEKHPVPFY 190
           +GW     + H TARY +GADGAN +  + L     H  R     A++       P+ F 
Sbjct: 144 EGWSLRTEDAHYTARYFIGADGANGVSAKLLGRAAGHHARDSFAAAVEAEVPIDDPLRFA 203

Query: 191 SCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAF-QFQFGKTVKSEK 249
             +  + +   Y+W   K G  +  G Y     +     LK  +  F + +  +T+++  
Sbjct: 204 MEMRLDYVPRGYAWIFPK-GDHLNVGIY----ARGSVKGLKASLVEFVRARLDQTLETRD 258

Query: 250 CTV-LFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDS 292
                 P   QD     D AFL+G+A G       EGI YA+ S
Sbjct: 259 IVGWRVPVSGQDRAPRTDGAFLVGDAGGLAEPMFGEGIFYAIAS 302


>UniRef50_C7YZG9 Putative uncharacterized protein n=2 Tax=Nectriaceae
           RepID=C7YZG9_NECH7
          Length = 417

 Score = 45.8 bits (107), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 90/387 (23%), Positives = 149/387 (38%), Gaps = 55/387 (14%)

Query: 1   MEHFDVAIIGLGPAGSALARKL-AGKMQVIALDKKH------QCGTEGFSKPCGGLLAPD 53
           M +  VAIIG GPAG  LAR L  G + V   + +       Q GT       G     +
Sbjct: 1   MGNRKVAIIGAGPAGCMLARLLHLGGVDVTVFEGEEHPNFRSQGGTLDLHTATGLAALKE 60

Query: 54  AQ--RSFIR----DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM 107
           A+    F+R    DG  L + V  N +   VK  D       N  +    I+R      +
Sbjct: 61  AKLFNEFLRHARYDGQYLAI-VDKNLEYLLVKNADG----PYNKIQERPEIDRSKLRELL 115

Query: 108 KSLIPASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRH--- 164
            S +P  V  +   L +   R     H     DG++       +VGADGA S VR+    
Sbjct: 116 SSSLPEDVIKWGHRLKKVEGRTLVFEHTTL--DGFD------VIVGADGAWSKVRKEIDP 167

Query: 165 -LYPDHQIRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYS---WSISK--DGYFIFGGAY 218
            L P++       ++    E      Y  +   S+   +     SI +  DG      ++
Sbjct: 168 DLVPEYSGIGLQELEVTDVENRAPDLYKLVNRGSVFAGWEGKRMSIQQMGDGSLSVYCSH 227

Query: 219 PMKDG--------QTRFTTLKEKMSAF----------QFQFGKTVKSEKCT--VLFPSRW 258
            +K+         +     +KE   A           + +    +   +CT   LF    
Sbjct: 228 VIKEADWMKPEKCEYDAGNIKEVAPALLNGLYKDWDPRLKRAIEMADGRCTPRSLFMLPV 287

Query: 259 QDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKL 318
            +    K    LIG+AA  ++  + EG++ ALD   +L   ++   +K + A  +A ++ 
Sbjct: 288 GEKWTHKPGLTLIGDAAHLMTPYAGEGVNQALDDASLLAKAIIGAADKDDEALDKAIQEF 347

Query: 319 RLKLFGKIVKSRCLTAPALRKWIMRSG 345
              +F ++   + LTA  ++ W+M  G
Sbjct: 348 EETMFARVGPVQKLTAELMQDWMMTPG 374


>UniRef50_C6A374 Geranylgeranyl hydrogenase n=9 Tax=Thermococcaceae
           RepID=C6A374_THESM
          Length = 375

 Score = 45.1 bits (105), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 46/167 (27%), Positives = 81/167 (48%), Gaps = 16/167 (9%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           +  +DVAIIG GP G+ LA  LA + +V+ L+ K+  G     K C G++  +       
Sbjct: 4   LMRYDVAIIGGGPVGNYLANLLASEFKVVVLEAKNSFG----GKACTGIMGAENY----- 54

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAA-SLTRNYQRSYININRHAFDLWM-KSLIPASVEVY 118
           + L LP + I N    +V    + +  + R   ++Y+ ++R   +  + ++ I    E Y
Sbjct: 55  EKLNLPKEAIINKLRGAVFYSRIQSFEIERPTPQAYV-VDRKLLERKLAENAIRHGAEYY 113

Query: 119 HDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHL 165
             +  R +  ++ K  V    + +E  I A + VGADG NS V + +
Sbjct: 114 MGA--RFLGFKNRKAIVQRFNEKFE--IEADFYVGADGLNSKVAQEI 156


>UniRef50_UPI000038E1B1 geranylgeranyl hydrogenase n=1 Tax=Ferroplasma acidarmanus fer1
           RepID=UPI000038E1B1
          Length = 393

 Score = 45.1 bits (105), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 70/295 (23%), Positives = 127/295 (43%), Gaps = 38/295 (12%)

Query: 4   FDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKP--CGGLLAPDAQRSFIR 60
           +DV + G GP+GS L+  L+    +V+ L++  + G     KP  C GL++   +R F  
Sbjct: 15  YDVIVSGAGPSGSYLSYLLSRNGYKVLQLEEHREVG-----KPVECTGLVS---ERVFKY 66

Query: 61  DGLTLPVDVIANPQIF--SVKTVDVAASLTRNYQRSYININRHAFDLWMKSL-IPASVEV 117
                 V+ +    +F  + K++ ++           I + R  FD  + ++ I A  + 
Sbjct: 67  VNSRSMVNEVHGANVFFPNGKSIHISKG------EKTIVMYRDDFDKDVSAMAIGAGADT 120

Query: 118 YHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAI 177
             ++        D    V +R +G  ++  A  +VGADGANS +R  L  +   +K ++ 
Sbjct: 121 RINARVLDAKVNDSYGEVKYRENGEIKYARANIIVGADGANSRIRLSLNYERP-KKIIST 179

Query: 178 QQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAF 237
            Q  +  H       + D    N +  S +  G+  FG A P  +  TR     + ++A 
Sbjct: 180 YQVDSSFH-------LDDQDDVNVFIGSENSKGF--FGWAVPSGE-ITRIGVGVDHVTAI 229

Query: 238 QFQFGKTVKSEKCTVL------FPSRWQDFVCGKDNAFLIGEAAGFISASSLEGI 286
           ++     VK  +  +L       P  +     G + + L+G+AAG +   S  GI
Sbjct: 230 KYFRNINVKFNRSQILGINAGPIPINYLSKTYG-NRSLLLGDAAGIVKPLSGGGI 283


>UniRef50_A3CSH0 Geranylgeranyl reductase n=1 Tax=Methanoculleus marisnigri JR1
           RepID=A3CSH0_METMJ
          Length = 403

 Score = 45.1 bits (105), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 46/170 (27%), Positives = 71/170 (41%), Gaps = 16/170 (9%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
            +D  ++G GPAGS  A  LA     +AL ++    T   +K CGG L+    R F+   
Sbjct: 6   EYDAVVVGGGPAGSTAACLLAEAGHSVALLERR---TYPRNKVCGGCLSQKTVR-FLDRV 61

Query: 63  LTLPVDVIANPQIFSVKTVDVAAS------LTRNYQRSYININRHAFDLWMKSLIP-ASV 115
            +LPV  +    +        A        LT +         R  +D ++  +   A  
Sbjct: 62  FSLPVPALRQAGLLDFTGTGYALYIGSRRILTEDLDEPVYFTGRERYDAFLAKMAARAGA 121

Query: 116 EVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHL 165
           EV+  +    I   D     +  +DG     +AR ++GADG +S VRR L
Sbjct: 122 EVHTGAEAAGI---DHARRTVTTSDG--DRYSARVIIGADGVHSRVRRTL 166


>UniRef50_B5MAB8 Putative salicylate 1-monooxygenase n=1 Tax=Rhodococcus sp. PY11
           RepID=B5MAB8_9NOCA
          Length = 413

 Score = 44.7 bits (104), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 53/175 (30%), Positives = 73/175 (41%), Gaps = 23/175 (13%)

Query: 6   VAIIGLGPAGSALARKLAGK-MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           V IIG G  G   A  L  + ++V  L++  Q G  G     G  + P+A R   R GL 
Sbjct: 3   VVIIGAGIGGLTAALTLRSRGIEVTVLEQAQQLGEIG----AGLQIGPNASRVLHRLGLA 58

Query: 65  LPVDVIANPQIFSVK----------TVDVAASLTRNYQRSYININRHAFD--LWMKSLIP 112
             +D IA     SV+             + AS T  +   Y++++R      L   ++ P
Sbjct: 59  GDLDPIALVVEESVRRRWATGEVLAKTTLGASATAQFGSPYLHLHRADLHHVLHTAAIDP 118

Query: 113 A----SVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRR 163
           A    +VEV  DS   +I   D    V     G      A  +VGADG NS VRR
Sbjct: 119 ARPGPAVEVVVDSRVERIEGVDGATPVAVTTSG--ARFAADVVVGADGINSQVRR 171


>UniRef50_C6PBK9 Geranylgeranyl reductase n=1 Tax=Thermoanaerobacterium
           thermosaccharolyticum DSM 571 RepID=C6PBK9_CLOTS
          Length = 387

 Score = 44.3 bits (103), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 77/318 (24%), Positives = 127/318 (39%), Gaps = 45/318 (14%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           +DV IIG GPAGS LAR+L+ +     L +K    T    K CGG + P   +      L
Sbjct: 2   YDVIIIGGGPAGSTLARRLSAQGYKALLIEKF---TMPRYKACGGGITPRCYKM-----L 53

Query: 64  TLPVDVIANPQIFSV-------KTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASV 115
            L +        + +       K+V +       YQ     ++R  FD ++    + +  
Sbjct: 54  DLDISDYVEDTTYKIAFKFPNNKSVVLETEKPIIYQ-----VDRTKFDKYLIDKAVESGC 108

Query: 116 EVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQI--RK 173
           +V+        +R  D   V+ + D        R LVGADG NS V    Y  + +   K
Sbjct: 109 DVHDGEKFLDFYR--DGKEVVVKTD--RGQYKTRILVGADGINSTVA---YKANLLNGEK 161

Query: 174 YVAIQ-QWFAEKHPVPFY--SCIFD-NSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTT 229
            +A++ + + +K  +       + D N+I   Y W   K      G    +    ++ + 
Sbjct: 162 GIALEAEVYVDKCDIEKVRGEVVVDFNAIKYGYGWVFPKKDRLSIGVGTFL----SKTSK 217

Query: 230 LKEKMSAFQFQFGKTVKSEKCTVL-----FPSRWQDFVCGKDNAFLIGEAAGFISASSLE 284
           +KE +S            E+C +      FP+  +D     D   LIG+A       + E
Sbjct: 218 IKENLSNM-IDENVVGNVEECKIYGHQLSFPN-GKDGTYNNDKVILIGDATRLADPFTGE 275

Query: 285 GISYALDSTDILRSVLLK 302
           GI  A+ + +I   V+ K
Sbjct: 276 GIYNAILTANISFDVIEK 293


>UniRef50_C1RER8 2-polyprenyl-6-methoxyphenol hydroxylase-like oxidoreductase n=1
           Tax=Cellulomonas flavigena DSM 20109 RepID=C1RER8_9CELL
          Length = 388

 Score = 43.9 bits (102), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 43/170 (25%), Positives = 67/170 (39%), Gaps = 28/170 (16%)

Query: 127 WREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEKHP 186
           W E D   V+  ADG   H+ A  LVGADG  S VRR L+P     +Y     W   +  
Sbjct: 139 WDERDDGVVVHLADG--THLPADVLVGADGLRSTVRRRLHPHEGAPRYAGYTAW---QGV 193

Query: 187 VPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKTVK 246
           VP      D+ +   +  ++ +  +F++   Y + D    +  +    +A +   G T  
Sbjct: 194 VPVGDLDVDDGV---FVNTLGRGVWFVY---YRLADDLVYWDGIVGPEAARRAGSGATSP 247

Query: 247 SEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDIL 296
            E     F             A   G A G ++A+      +AL  TD+ 
Sbjct: 248 REMLLRAF-------------AGWPGPARGLVAATP----EHALRPTDVF 280


>UniRef50_B4U8N3 Geranylgeranyl reductase n=1 Tax=Hydrogenobaculum sp. Y04AAS1
           RepID=B4U8N3_HYDS0
          Length = 348

 Score = 43.5 bits (101), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 72/309 (23%), Positives = 118/309 (38%), Gaps = 30/309 (9%)

Query: 5   DVAIIGLGPAGSALARKLAGK-MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           DV IIG G AGS+ A +LA K + VI +D +    T G    C   +     +    D  
Sbjct: 8   DVLIIGGGLAGSSAAHQLAKKGVDVIIVDSRK---TIGVPVQCAEFIPKQLMQKKFEDYF 64

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQRSY-----ININRHAFDLWM-KSLIPASVEV 117
              V          V+ ++   ++  + ++ Y     + ++R  FD  + +  I +    
Sbjct: 65  KNSV----------VQEIENMLTIEPDNKKVYSGSKGVMVDRKVFDANIFQEAIKSGARA 114

Query: 118 YHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYP-DHQIRKYVA 176
           +  ++    +   DK   I +A     ++   Y+VGADG  S V   ++   H++   V 
Sbjct: 115 FLKTIFIGFY---DKNTAILKAKDDVYYVEFDYIVGADGPRSSVMEKVFSKKHELA--VC 169

Query: 177 IQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAY--PMKDGQTRFTTLKEKM 234
            Q+    K P+     +F   I   Y W   K+ Y   G       KD       L  K 
Sbjct: 170 AQRRCKLKEPLKDIVIVFREYIKGGYGWIFPKNNYANVGIGIDTAFKDDPKYVLELFIK- 228

Query: 235 SAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTD 294
            A    F +    E      P    D +    N  L G+A GF    +  GI  A+ S +
Sbjct: 229 DAVSMGFIENNCDESSGGFLPLDGIDTLVSS-NVALCGDAGGFCHPITGGGIPQAVVSGN 287

Query: 295 ILRSVLLKQ 303
           +L   +L+ 
Sbjct: 288 MLAQYILEN 296


>UniRef50_C9NII0 Monooxygenase FAD-binding n=1 Tax=Streptomyces flavogriseus ATCC
           33331 RepID=C9NII0_9ACTO
          Length = 527

 Score = 43.5 bits (101), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 47/167 (28%), Positives = 70/167 (41%), Gaps = 14/167 (8%)

Query: 4   FDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
            DV I+G GP G  LA +LA   ++ + L++     TE  +    GL+     R   R G
Sbjct: 2   LDVVIVGGGPNGLTLACELALAGVRPVVLERLAGPKTEARAN---GLVG-QVVRMLDRRG 57

Query: 63  LTLPVDVIANPQ------IFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVE 116
           L   +     P       +F   T+D+      N          H   +  +  +   V+
Sbjct: 58  LYARISESEEPPRPAPRYMFGAFTLDLTGLGDSNPVCLLPAPQEHIEKVLAERAVELGVD 117

Query: 117 VYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRR 163
           +        + +EDD   +   ADG  +  T RYLVGADG +SMVRR
Sbjct: 118 LRRGQEVTDVQQEDDFVRITL-ADG--ETFTTRYLVGADGGHSMVRR 161


>UniRef50_A7IDT6 Monooxygenase FAD-binding n=9 Tax=Proteobacteria RepID=A7IDT6_XANP2
          Length = 509

 Score = 43.1 bits (100), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 51/182 (28%), Positives = 79/182 (43%), Gaps = 26/182 (14%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGK-MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           + FDV I+GLGP G+ LA  L  + +  + L+++    TE +  P       +  R F  
Sbjct: 10  DQFDVVIVGLGPVGATLANLLGLQGVSTLVLERE----TEAYHLPRAVHFDDEVMRVFQT 65

Query: 61  DGLT---LPVDVIANPQIFSVKTVDVAASLTRNYQRS--------YININRHAFDLW--M 107
            GL     P   I NP    ++ VD   +L  ++ R+        + +   H  DL   +
Sbjct: 66  IGLADEITPCTRI-NP---GMRFVDANGALLMDWPRAPDVGELGWHASYRFHQPDLERIL 121

Query: 108 KSLIPASVEVYHDSLCRKIWREDDKWHVIFRAD----GWEQHITARYLVGADGANSMVRR 163
           +  +     V   + C     EDD   V  R +    G  +   ARY+VG DGA S+VRR
Sbjct: 122 REGLKRFACVRVQTRCDAFAFEDDGEAVTVRYEDLDTGRLRQAGARYVVGCDGARSLVRR 181

Query: 164 HL 165
            +
Sbjct: 182 FI 183


>UniRef50_Q6KZ83 FixC protein n=1 Tax=Picrophilus torridus RepID=Q6KZ83_PICTO
          Length = 396

 Score = 42.7 bits (99), Expect = 0.021,   Method: Compositional matrix adjust.
 Identities = 81/326 (24%), Positives = 140/326 (42%), Gaps = 53/326 (16%)

Query: 1   MEHFDVAIIGLGPAGSALARKLA--GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSF 58
           M  +D  ++G GPAGSA A KLA  GK + + L++  + G++  S   G ++  D   S 
Sbjct: 1   MLDYDAVVVGAGPAGSAAALKLASLGK-KTLVLERGPEPGSKNVS---GAMIRKDFVTSV 56

Query: 59  IRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVY 118
             DG  LPV+        S+ + +   SL   Y  +     R  FD W+ S+   +  + 
Sbjct: 57  FGDG--LPVERNVERMKVSLYSSERPVSL-EFYPENLATTGRLKFDKWLSSVSEKAGAI- 112

Query: 119 HDSLCRKIWREDDKWHVIFRADGW---EQHITARYLVGADGANSM------VRRHLYPDH 169
              +  K    D KW    RA G       ++ R +V A+G NS+      ++R L PD 
Sbjct: 113 ---VIPKTTVTDIKWK-DGRATGVVTDRGEVSTRSIVLAEGVNSLLAISSGIKRELKPDQ 168

Query: 170 QIR--KYVAIQQWFAEKHPVPFYSCIFDNSITNC-YSWSISK-DGYFIFGGAYPMKDGQT 225
            ++  KYV    +  +K  +   + +F+ S  +   SW I + D     G  Y  +D  +
Sbjct: 169 AVQTVKYV----YSIKKEQI---NSMFNLSSDDAGLSWRIIRADPVLTAGFLYTYRDSVS 221

Query: 226 ------------------RFTTLKEKMSAFQFQF-GKTVKSEKCTVLFPSRWQDFVCGKD 266
                                 +  K + F+  F G +++     ++  + + D +  K 
Sbjct: 222 VGVGAPISGLIEKKIKPEELMDMFMKYTGFEDLFKGFSLREYSAKIIPEAGFPDMLASKS 281

Query: 267 NAFLIGEAAGFISASSLEGISYALDS 292
           N +L G+A G +   + +GIS A++S
Sbjct: 282 NVYLCGDALGLVDPLTFDGISPAIES 307


>UniRef50_A1RY40 Geranylgeranyl reductase n=1 Tax=Thermofilum pendens Hrk 5
           RepID=A1RY40_THEPD
          Length = 387

 Score = 42.4 bits (98), Expect = 0.023,   Method: Compositional matrix adjust.
 Identities = 75/340 (22%), Positives = 122/340 (35%), Gaps = 50/340 (14%)

Query: 3   HFDVAIIGLGPAGSALARKLAGK-MQVIALDKKHQCGTEGFSKPCG-GLLA--------- 51
            +D A++G GPAG   AR LA K  +V  L+K          KPCG G+ A         
Sbjct: 2   QYDAAVVGAGPAGLMFARVLASKGFRVAVLEKNETLAV----KPCGEGISARVLQTAEIN 57

Query: 52  -PDAQRSFIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSL 110
             D QR F+   +   V V  N +   +K            +  Y+   R+   +  +  
Sbjct: 58  RSDTQR-FVSHAIKGAVVVAPNGRKVVIK---------EEGELGYVIDKRNFLRVMGEYA 107

Query: 111 IPASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQ 170
                ++Y     +++  ++  W V  R       + AR LVGADG  S   + L  +  
Sbjct: 108 ASYGADIYMKEPVKEVVFKNGHWTVRART----VELEARLLVGADGYLSYTAKALGLEKP 163

Query: 171 -IRKYVAIQQWFAE----KHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQT 225
             R+ +   Q+       + P   Y  + +      Y W   KDG     G         
Sbjct: 164 GERRVIPTVQYVMPNVELEDPDMTYFFLGNEVAPKGYVWIFPKDGRLANVGIGVQGASPK 223

Query: 226 RFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEG 285
            +     K +   F   + ++     V       + V   ++A L+GEAAG +   +  G
Sbjct: 224 AYLDKFIKNNPSIFGKARILEFRGAAVTIGGMLSEIVS--EHAMLVGEAAGQVIPLTGGG 281

Query: 286 ISYALDSTDILRSVL-------------LKQPEKLNTAYW 312
           I  ++    I   V              L++ +KL   YW
Sbjct: 282 IHTSIAGGKIAAEVASKALAEGDLSKKRLEEYKKLYNEYW 321


>UniRef50_O26377 Digeranylgeranylglycerophospholipid reductase 1 n=2
           Tax=Methanobacteriaceae RepID=GGR1_METTH
          Length = 397

 Score = 42.4 bits (98), Expect = 0.028,   Method: Compositional matrix adjust.
 Identities = 51/172 (29%), Positives = 74/172 (43%), Gaps = 21/172 (12%)

Query: 3   HFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCG-----TEGFSKPCGGL--LAPDA 54
             DV +IG GPAGS  A+  A G   V+ +DKK + G      EG S   GGL  L  + 
Sbjct: 7   EVDVLVIGAGPAGSTAAKHAALGGADVLLIDKKSEIGAPKRCAEGVS--IGGLESLGIEP 64

Query: 55  QRSFIRDGLTLPVDVIANPQIFSVKTVDV--AASLTRNYQRSYININRHAFDLWMK-SLI 111
              +I    T  +D +   ++ S    DV   +      +  YI + R  FD +M     
Sbjct: 65  NPRWI----TKKLDGV---RMVSPNGTDVWLTSDKVELPEAGYI-LERKVFDKFMAMDAA 116

Query: 112 PASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRR 163
            A   +   ++   + R DD + V     G +  I AR ++ ADG  S V R
Sbjct: 117 RAGSRIMVKTIATGMERTDDGYLVSAECMGEKFEIKARIVIAADGPESRVAR 168


>UniRef50_B2HF07 3-(3-hydroxy-phenyl) propionate hydroxylase n=6 Tax=Actinomycetales
           RepID=B2HF07_MYCMM
          Length = 514

 Score = 42.4 bits (98), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 48/180 (26%), Positives = 83/180 (46%), Gaps = 20/180 (11%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           +    V I+G GP G   A  LA   ++ + L++     T+ + +P    L  +  R   
Sbjct: 9   IRQVPVVIVGAGPTGITAATLLAQYGVESMVLER----WTDVYPQPRAVHLDDEIYRVIA 64

Query: 60  RDGLTLPVDVIANPQIFSVKTVD----VAASLTRNYQRSYININR-HAFDL-WMKSLIPA 113
           R G+      I+ P    ++ +D    V     R+  RS     + + FD   +++L+ A
Sbjct: 65  RLGIADEFAAISRP-TQGLRLLDNRFNVLTEFHRDPARSLHGFPQANMFDQPELETLLRA 123

Query: 114 SVEVYHDSLCR------KIWREDDKWHVIF--RADGWEQHITARYLVGADGANSMVRRHL 165
           +++ Y  +  R      +I   ++   V F  R+DG   H+ A Y++G DGANSMVR H+
Sbjct: 124 NLKRYAHAQLRGGAEVIEICDTNELLRVTFTDRSDGRVHHVDAEYVLGCDGANSMVRSHV 183


>UniRef50_D2RGA8 Dehydrogenase (Flavoprotein)-like protein n=1 Tax=Archaeoglobus
           profundus DSM 5631 RepID=D2RGA8_ARCPR
          Length = 357

 Score = 42.0 bits (97), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 71/299 (23%), Positives = 121/299 (40%), Gaps = 37/299 (12%)

Query: 6   VAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTL 65
           + I+G GPAGS  A  +A K   + + ++H   + GF   C GL++    R  ++     
Sbjct: 2   ILIVGGGPAGSLSA--IALKNYDVTVVEEHS--SAGFPVQCAGLISERCYRE-LKKFSDC 56

Query: 66  PVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLCRK 125
            V+ I     FS        S+    +   + + R   D   + L+  + E Y + + + 
Sbjct: 57  KVNDIRGAVFFSPNN-----SVELEGKVGAVVVERKLLD---RDLLAKASE-YANVMIKT 107

Query: 126 IWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEKH 185
            +   +K   + R+ G +  +   Y++GADG  S V  +++   +   Y A+Q       
Sbjct: 108 KFLGVEKGKAVLRSMGKKIELDYDYIIGADGVYSTVS-NVFNFKKPEVYSALQITCR--- 163

Query: 186 PVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPM----KDGQTRFTTLKEKMSAFQFQF 241
               + CI D+ +   + +S     YF +  A P     K G          M       
Sbjct: 164 ----FECISDDLVEIYFGFS----DYFCY--AIPFDEFAKIGVISSQNPMPVMRRLLRWL 213

Query: 242 GKTVKS---EKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILR 297
           GK VK    E      P    DFV  KD   LIG++AG +   +  G+ Y L + + L+
Sbjct: 214 GKRVKGSVLELNAGAIPIGLVDFV--KDRVMLIGDSAGMVKPYTGGGLYYILKAVEKLK 270


>UniRef50_Q2RLB4 Geranylgeranyl reductase n=1 Tax=Moorella thermoacetica ATCC 39073
           RepID=Q2RLB4_MOOTA
          Length = 341

 Score = 41.2 bits (95), Expect = 0.063,   Method: Compositional matrix adjust.
 Identities = 73/299 (24%), Positives = 115/299 (38%), Gaps = 29/299 (9%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCG----GLLAPDAQR 56
           M  +D  + G GPAGS  AR +A     + L +K      G+   C      L+A  ++ 
Sbjct: 1   MLKYDAVVAGAGPAGSTAARVVAAAGARVLLIEKRA--RVGYPVQCAEYVPALIA--SEV 56

Query: 57  SFIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASV 115
            F    + L V  +     F   TV      T      YI +NR  FD  + +  + A  
Sbjct: 57  DFGEKSIALAVGTLVT--FFPDGTV------TSTPAPGYI-LNREVFDASLAEGAVKAGA 107

Query: 116 EVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMV-RRHLYPDHQIRKY 174
           E++  +    +    D   +I +A+G  Q + A  ++GADG  S+V R   +P   +   
Sbjct: 108 ELWLKATVEDL---TDTSLIIRQANGRRQEVEAGVIIGADGPLSLVARTRGWPRATL--A 162

Query: 175 VAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFG-GAYPMKDGQTRFTTLKEK 233
            A+Q   A   P+      FD      Y+W   K      G G  P +   T    L   
Sbjct: 163 AAVQVEMALPEPMQVTRVYFDPLYRGGYAWVFPKGKTANVGVGLVPGEI--TPAAALTHF 220

Query: 234 MSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDS 292
           +    +Q    V+     +     +Q+   G+    L G+A GF    +  GI  A+ S
Sbjct: 221 LRRLGWQQQNIVRRTGGLIPVAGPYQEVHRGR--VLLCGDAGGFTHPVTGAGILTAILS 277


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_A1AHM5 Protein cbrA n=54 Tax=Enterobacteriaceae RepID=C...   515   e-144
UniRef50_B6ZQD5 Protein CbrA n=1 Tax=Escherichia coli O157:H7 st...   473   e-132
UniRef50_D2THX1 Putative uncharacterized protein n=4 Tax=Bacteri...   471   e-131
UniRef50_C3KYD3 CbrA protein n=14 Tax=Bacteria RepID=C3KYD3_CLOB6     409   e-112
UniRef50_UPI00019786F4 putative oxidoreductase n=1 Tax=Helicobac...   347   3e-94
UniRef50_Q7VFG9 Putative uncharacterized protein n=1 Tax=Helicob...   345   1e-93
UniRef50_B8FUH4 FAD dependent oxidoreductase n=3 Tax=Clostridial...   335   2e-90
UniRef50_C6JQS4 FAD dependent oxidoreductase n=1 Tax=Fusobacteri...   293   5e-78
UniRef50_Q1IMS5 Geranylgeranyl reductase n=1 Tax=Candidatus Kori...   250   8e-65
UniRef50_D1RCG6 Geranylgeranyl reductase family protein n=1 Tax=...   236   6e-61
UniRef50_B9L6H5 Geranylgeranyl hydrogenase n=2 Tax=Nautiliaceae ...   235   2e-60
UniRef50_A6QA88 Geranylgeranyl hydrogenase n=1 Tax=Sulfurovum sp...   231   2e-59
UniRef50_Q1PX22 Putative uncharacterized protein n=1 Tax=Candida...   227   5e-58
UniRef50_B5W6L5 Geranylgeranyl reductase n=2 Tax=Arthrospira Rep...   225   2e-57
UniRef50_Q649G8 Geranylgeranyl reductase n=3 Tax=environmental s...   224   4e-57
UniRef50_Q8DGN7 Tlr2279 protein n=5 Tax=Cyanobacteria RepID=Q8DG...   215   2e-54
UniRef50_P96800 Uncharacterized protein Mbar_A1602 n=1 Tax=Metha...   212   1e-53
UniRef50_P26172 Geranylgeranyl diphosphate reductase n=34 Tax=Ba...   212   2e-53
UniRef50_A6CDB5 Geranylgeranyl reductase n=1 Tax=Planctomyces ma...   210   8e-53
UniRef50_B3ECC8 Geranylgeranyl reductase n=3 Tax=Chlorobium RepI...   209   1e-52
UniRef50_Q3A1Y0 Flavoprotein-containing dehydrogenase n=1 Tax=Pe...   208   3e-52
UniRef50_A5D4V1 Dehydrogenases n=1 Tax=Pelotomaculum thermopropi...   207   5e-52
UniRef50_B0JID7 Geranylgeranyl reductase n=8 Tax=Cyanobacteria R...   206   1e-51
UniRef50_B9M019 FAD dependent oxidoreductase n=1 Tax=Geobacter s...   206   1e-51
UniRef50_B5YGK5 Geranylgeranyl hydrogenase, putative n=1 Tax=The...   205   3e-51
UniRef50_Q11W52 Probable electron transfer flavoprotein n=1 Tax=...   202   2e-50
UniRef50_Q2NER9 Digeranylgeranylglycerophospholipid reductase 3 ...   192   2e-47
UniRef50_B8GFT3 Geranylgeranyl reductase n=1 Tax=Methanosphaerul...   188   4e-46
UniRef50_UPI0001C42077 geranylgeranyl reductase family protein n...   186   1e-45
UniRef50_O29786 Digeranylgeranylglycerophospholipid reductase n=...   185   3e-45
UniRef50_A8M2V9 Geranylgeranyl reductase n=5 Tax=Actinomycetales...   184   3e-45
UniRef50_Q2S264 FAD dependent oxidoreductase, putative n=1 Tax=S...   183   1e-44
UniRef50_Q6ALA8 Related to dehydrogenases (Flavoproteins) n=1 Ta...   181   3e-44
UniRef50_B3QZ41 Geranylgeranyl reductase n=12 Tax=Chlorobiaceae ...   181   5e-44
UniRef50_A3V9M1 Geranylgeranyl reductase n=1 Tax=Rhodobacterales...   178   2e-43
UniRef50_UPI0000D53425 oxidoreductase n=1 Tax=Psychroflexus torq...   178   3e-43
UniRef50_A0B5F9 Geranylgeranyl reductase n=1 Tax=Methanosaeta th...   173   7e-42
UniRef50_Q8TMB3 Putative uncharacterized protein n=1 Tax=Methano...   171   3e-41
UniRef50_A8ME14 Geranylgeranyl reductase n=1 Tax=Caldivirga maqu...   170   8e-41
UniRef50_C0GUA1 Geranylgeranyl reductase n=1 Tax=Desulfonatronos...   169   1e-40
UniRef50_C6CUN6 Monooxygenase FAD-binding n=1 Tax=Paenibacillus ...   166   8e-40
UniRef50_B1LSG8 Geranylgeranyl reductase n=27 Tax=Proteobacteria...   165   2e-39
UniRef50_UPI0001C421FD hypothetical protein BpOF4_18960 n=1 Tax=...   160   8e-38
UniRef50_C3NB54 FAD dependent oxidoreductase n=12 Tax=Sulfolobac...   158   3e-37

Sequences not found previously or not previously below threshold:

UniRef50_Q2RKB3 Geranylgeranyl reductase n=1 Tax=Moorella thermo...   197   7e-49
UniRef50_Q4JN54 Putative uncharacterized protein n=1 Tax=uncultu...   191   3e-47
UniRef50_A1U6D3 Geranylgeranyl reductase n=2 Tax=Marinobacter Re...   183   9e-45
UniRef50_C8X2V2 Geranylgeranyl reductase n=1 Tax=Desulfohalobium...   180   8e-44
UniRef50_C6PBK9 Geranylgeranyl reductase n=1 Tax=Thermoanaerobac...   178   2e-43
UniRef50_C9R7U9 Geranylgeranyl reductase n=1 Tax=Ammonifex degen...   178   4e-43
UniRef50_C6BUN1 Geranylgeranyl reductase n=1 Tax=Desulfovibrio s...   172   2e-41
UniRef50_Q8DJ25 Tll1404 protein n=7 Tax=Cyanobacteria RepID=Q8DJ...   171   4e-41
UniRef50_A3CSH0 Geranylgeranyl reductase n=1 Tax=Methanoculleus ...   171   5e-41
UniRef50_B8G4M6 Geranylgeranyl reductase n=6 Tax=Chloroflexaceae...   170   6e-41
UniRef50_D2B4C1 Geranylgeranyl reductase n=4 Tax=Actinomycetales...   170   8e-41
UniRef50_A8URP5 Putative uncharacterized protein n=2 Tax=Aquific...   169   9e-41
UniRef50_UPI0001C15A6F geranylgeranyl reductase n=2 Tax=Nostocac...   168   3e-40
UniRef50_Q648X7 Geranylgeranyl reductase n=4 Tax=environmental s...   168   3e-40
UniRef50_B8HM17 Geranylgeranyl reductase n=1 Tax=Cyanothece sp. ...   167   5e-40
UniRef50_A0LRI0 Geranylgeranyl reductase n=38 Tax=Actinomycetale...   166   8e-40
UniRef50_B3QWR4 Geranylgeranyl reductase n=1 Tax=Chloroherpeton ...   166   1e-39
UniRef50_A8LAV2 Geranylgeranyl reductase n=5 Tax=Actinomycetales...   165   2e-39
UniRef50_C5A6E5 Digeranylgeranylglycerophospholipid reductase n=...   164   5e-39
UniRef50_O26377 Digeranylgeranylglycerophospholipid reductase 1 ...   163   9e-39
UniRef50_C9RJJ2 Geranylgeranyl reductase n=1 Tax=Fibrobacter suc...   163   1e-38
UniRef50_B3QNV5 Geranylgeranyl reductase n=4 Tax=Chlorobiaceae R...   162   2e-38
UniRef50_Q31QX9 Geranylgeranyl reductase n=2 Tax=Synechococcus e...   162   2e-38
UniRef50_Q12YW2 Digeranylgeranylglycerophospholipid reductase 1 ...   161   3e-38
UniRef50_D1CHF7 Geranylgeranyl reductase n=1 Tax=Thermobaculum t...   161   4e-38
UniRef50_A8UYA2 Putative uncharacterized protein n=2 Tax=Aquific...   161   4e-38
UniRef50_B1L612 Geranylgeranyl reductase n=1 Tax=Candidatus Kora...   159   1e-37
UniRef50_C4XQT1 Geranylgeranyl reductase n=2 Tax=Desulfovibrio R...   157   6e-37
UniRef50_D2RHK2 Geranylgeranyl reductase n=2 Tax=Archaeoglobacea...   156   2e-36
UniRef50_UPI000050FC1D geranylgeranyl reductase n=1 Tax=Brevibac...   155   2e-36
UniRef50_B4U8N3 Geranylgeranyl reductase n=1 Tax=Hydrogenobaculu...   154   6e-36
UniRef50_Q6L1J9 Geranylgeranyl hydrogenase n=3 Tax=Thermoplasmat...   154   6e-36
UniRef50_A3JWR6 Geranylgeranyl reductase n=1 Tax=Rhodobacterales...   152   1e-35
UniRef50_B4WHJ4 Putative uncharacterized protein n=1 Tax=Synecho...   152   1e-35
UniRef50_O27753 Digeranylgeranylglycerophospholipid reductase 2 ...   152   2e-35
UniRef50_Q2JG94 Putative uncharacterized protein n=1 Tax=Frankia...   152   2e-35
UniRef50_D1CDE0 Geranylgeranyl reductase n=1 Tax=Thermobaculum t...   152   2e-35
UniRef50_Q2NFZ1 Digeranylgeranylglycerophospholipid reductase 1 ...   151   4e-35
UniRef50_D1UBF5 Geranylgeranyl reductase n=1 Tax=Desulfovibrio a...   151   4e-35
UniRef50_Q3A4T4 Dehydrogenase, flavoprotein containing n=1 Tax=P...   151   5e-35
UniRef50_Q0W1J4 Predicted FAD-dependent oxidoreductase n=2 Tax=E...   150   6e-35
UniRef50_A0QR89 Geranylgeranyl reductase n=7 Tax=Mycobacterium R...   150   7e-35
UniRef50_D1UBL8 Geranylgeranyl reductase n=1 Tax=Desulfovibrio a...   149   1e-34
UniRef50_B4UA54 Geranylgeranyl reductase n=1 Tax=Hydrogenobaculu...   149   1e-34
UniRef50_A1RY40 Geranylgeranyl reductase n=1 Tax=Thermofilum pen...   149   1e-34
UniRef50_A2BVI2 NAD binding site n=7 Tax=Prochlorococcus marinus...   149   2e-34
UniRef50_A6UWL1 Digeranylgeranylglycerophospholipid reductase n=...   149   2e-34
UniRef50_A8M3W4 Geranylgeranyl reductase n=1 Tax=Salinispora are...   148   3e-34
UniRef50_B4CVZ2 Geranylgeranyl reductase n=1 Tax=Chthoniobacter ...   148   3e-34
UniRef50_Q12X19 Geranylgeranyl reductase n=1 Tax=Methanococcoide...   147   4e-34
UniRef50_Q31RA2 Geranylgeranyl reductase n=13 Tax=cellular organ...   147   5e-34
UniRef50_Q2RLB4 Geranylgeranyl reductase n=1 Tax=Moorella thermo...   147   6e-34
UniRef50_A3EQU0 Geranylgeranyl reductase family protein n=2 Tax=...   147   7e-34
UniRef50_D2VJZ4 CMF receptor CMFR1 n=1 Tax=Naegleria gruberi Rep...   147   7e-34
UniRef50_Q6L0M1 Digeranylgeranylglycerophospholipid reductase n=...   146   1e-33
UniRef50_Q3JCF5 Geranylgeranyl reductase n=2 Tax=Nitrosococcus o...   146   1e-33
UniRef50_D1YYN0 Geranylgeranyl reductase n=1 Tax=Methanocella pa...   146   1e-33
UniRef50_A5D5E0 Dehydrogenases n=1 Tax=Pelotomaculum thermopropi...   145   2e-33
UniRef50_UPI000038E1B1 geranylgeranyl hydrogenase n=1 Tax=Ferrop...   145   3e-33
UniRef50_B1L6M6 Geranylgeranyl reductase n=1 Tax=Candidatus Kora...   143   9e-33
UniRef50_Q8TUV8 Digeranylgeranylglycerophospholipid reductase 2 ...   143   9e-33
UniRef50_A9A398 Geranylgeranyl reductase n=4 Tax=Thaumarchaeota ...   142   2e-32
UniRef50_A3CW88 Geranylgeranyl reductase n=1 Tax=Methanoculleus ...   142   2e-32
UniRef50_A3MV77 Geranylgeranyl reductase n=5 Tax=Thermoproteacea...   141   3e-32
UniRef50_Q30ZB0 Geranylgeranyl reductase n=1 Tax=Desulfovibrio d...   141   3e-32
UniRef50_C6HZ38 Geranylgeranyl reductase n=1 Tax=Leptospirillum ...   141   3e-32
UniRef50_Q9CA67 Geranylgeranyl diphosphate reductase, chloroplas...   140   8e-32
UniRef50_D1X0J5 Geranylgeranyl reductase n=1 Tax=Streptomyces sp...   139   1e-31
UniRef50_Q9U641 Conditioned medium factor receptor 1 n=1 Tax=Dic...   139   2e-31
UniRef50_Q46C42 Geranylgeranyl reductase n=5 Tax=Methanosarcina ...   138   2e-31
UniRef50_C3XVJ7 Putative uncharacterized protein n=1 Tax=Branchi...   138   3e-31
UniRef50_C0ZA99 Electron transfer flavoprotein-quinone oxidoredu...   137   7e-31
UniRef50_A1RZG7 Geranylgeranyl reductase n=1 Tax=Thermofilum pen...   137   7e-31
UniRef50_D2QMD3 Monooxygenase FAD-binding protein n=5 Tax=Bacter...   136   1e-30
UniRef50_A8JAG1 Predicted protein n=1 Tax=Chlamydomonas reinhard...   136   1e-30
UniRef50_UPI00018742EF geranylgeranyl reductase n=1 Tax=Coryneba...   135   2e-30
UniRef50_A3HTX2 FAD dependent oxidoreductase, putative n=1 Tax=A...   134   5e-30
UniRef50_C8QXS9 Monooxygenase FAD-binding n=1 Tax=Desulfurivibri...   133   8e-30
UniRef50_C7LZD6 Geranylgeranyl reductase n=1 Tax=Acidimicrobium ...   133   1e-29
UniRef50_Q58915 Uncharacterized protein MJ1520 n=11 Tax=Methanoc...   133   1e-29
UniRef50_A4X7I8 Geranylgeranyl reductase n=25 Tax=Actinomycetale...   133   1e-29
UniRef50_O26821 Conserved protein n=1 Tax=Methanothermobacter th...   132   2e-29
UniRef50_C9N331 Geranylgeranyl reductase n=3 Tax=Streptomyces Re...   131   3e-29
UniRef50_B1L7J1 Dehydrogenase (Flavoprotein) n=1 Tax=Candidatus ...   131   3e-29
UniRef50_B4CWA5 Monooxygenase FAD-binding n=1 Tax=Chthoniobacter...   131   4e-29
UniRef50_A0M1U0 Oxidoreductase n=2 Tax=Flavobacteriaceae RepID=A...   130   7e-29
UniRef50_C5CID7 FAD dependent oxidoreductase n=1 Tax=Kosmotoga o...   130   7e-29
UniRef50_A6GD06 Geranylgeranyl reductase n=1 Tax=Plesiocystis pa...   129   1e-28
UniRef50_B8FIZ7 Geranylgeranyl reductase n=1 Tax=Desulfatibacill...   129   1e-28
UniRef50_Q1AWH0 Geranylgeranyl reductase n=1 Tax=Rubrobacter xyl...   129   2e-28
UniRef50_A9G8G6 Monooxygenase family protein n=1 Tax=Sorangium c...   128   3e-28
UniRef50_A7BBW6 Putative uncharacterized protein n=1 Tax=Actinom...   127   4e-28
UniRef50_B9LNF2 Geranylgeranyl reductase n=11 Tax=Halobacteriace...   127   7e-28
UniRef50_B5Y9L9 FAD binding domain, putative n=1 Tax=Coprothermo...   127   7e-28
UniRef50_B5YDH3 FAD dependent oxidoreductase, putative n=2 Tax=D...   127   7e-28
UniRef50_A3W734 Geranylgeranyl reductase n=4 Tax=Rhodobacteracea...   126   1e-27
UniRef50_A5FDA0 FAD dependent oxidoreductase n=2 Tax=Bacteroidet...   126   1e-27
UniRef50_C6QH96 Geranylgeranyl reductase n=2 Tax=Alphaproteobact...   126   1e-27
UniRef50_B4X0T8 FAD dependent oxidoreductase, putative n=2 Tax=A...   126   1e-27
UniRef50_Q1VX49 FAD dependent oxidoreductase, putative n=1 Tax=P...   126   1e-27
UniRef50_D2RGA8 Dehydrogenase (Flavoprotein)-like protein n=1 Ta...   126   1e-27
UniRef50_C9RKL4 FAD dependent oxidoreductase n=1 Tax=Fibrobacter...   125   2e-27
UniRef50_B8GUG5 Geranylgeranyl reductase n=5 Tax=Gammaproteobact...   124   3e-27
UniRef50_A6BZI3 Probable alkylhalidase n=1 Tax=Planctomyces mari...   124   3e-27
UniRef50_D1BBC7 Geranylgeranyl reductase family protein n=11 Tax...   124   4e-27
UniRef50_C5CCQ4 Geranylgeranyl reductase family protein n=5 Tax=...   124   5e-27
UniRef50_B8ES76 Monooxygenase FAD-binding n=1 Tax=Methylocella s...   124   5e-27
UniRef50_C8VZJ8 Electron-transferring-flavoproteindehydrogenase ...   123   1e-26
UniRef50_Q01YQ3 Geranylgeranyl reductase n=1 Tax=Candidatus Soli...   122   1e-26
UniRef50_Q2NEQ6 Predicted dehydrogenase n=1 Tax=Methanosphaera s...   122   2e-26
UniRef50_B1XX19 Monooxygenase FAD-binding n=3 Tax=Burkholderiale...   122   2e-26
UniRef50_Q24QW7 Putative uncharacterized protein n=1 Tax=Desulfi...   122   2e-26
UniRef50_C8SW54 Monooxygenase FAD-binding n=1 Tax=Mesorhizobium ...   122   3e-26
UniRef50_D1JEF0 Putative uncharacterized protein n=1 Tax=uncultu...   121   3e-26
UniRef50_C0VR61 Geranylgeranyl reductase n=2 Tax=Corynebacterium...   121   3e-26
UniRef50_UPI0001787E07 monooxygenase FAD-binding protein n=1 Tax...   121   4e-26
UniRef50_C7M2T6 Geranylgeranyl reductase n=1 Tax=Acidimicrobium ...   121   5e-26
UniRef50_O29239 Bacteriochlorophyll synthase, 43 kDa subunit (Ch...   120   6e-26
UniRef50_Q05TK1 Putative electron transfer oxidoreductase n=1 Ta...   120   9e-26
UniRef50_C8SAI9 Geranylgeranyl reductase n=1 Tax=Ferroglobus pla...   120   1e-25
UniRef50_A1KG38 Possible oxidoreductase n=11 Tax=Mycobacterium R...   119   1e-25
UniRef50_C7PJY7 Geranylgeranyl reductase n=1 Tax=Chitinophaga pi...   119   1e-25
UniRef50_Q6KZ83 FixC protein n=1 Tax=Picrophilus torridus RepID=...   119   2e-25
UniRef50_C6A374 Geranylgeranyl hydrogenase n=9 Tax=Thermococcace...   119   2e-25
UniRef50_Q7U5F1 Predicted dehydrogenase (COG0644) n=20 Tax=Cyano...   119   2e-25
UniRef50_D2LI13 Monooxygenase FAD-binding n=1 Tax=Rhodomicrobium...   119   2e-25
UniRef50_C0QF41 Putative dehydrogenase n=1 Tax=Desulfobacterium ...   119   2e-25
UniRef50_A3TNM0 Putative oxidoreductase n=1 Tax=Janibacter sp. H...   119   2e-25
UniRef50_Q26DN3 Putative uncharacterized protein n=1 Tax=Flavoba...   118   2e-25
UniRef50_A1T3S9 Geranylgeranyl reductase n=10 Tax=Actinomycetale...   118   2e-25
UniRef50_A8THG7 Geranylgeranyl reductase n=1 Tax=Methanococcus v...   118   3e-25
UniRef50_D0L4V5 Geranylgeranyl reductase n=6 Tax=Actinomycetales...   118   3e-25
UniRef50_Q2FLI3 Geranylgeranyl reductase n=1 Tax=Methanospirillu...   118   3e-25
UniRef50_B2J4Q2 FAD dependent oxidoreductase n=1 Tax=Nostoc punc...   117   4e-25
UniRef50_A1RWE4 FAD dependent oxidoreductase n=1 Tax=Thermofilum...   117   5e-25
UniRef50_C4RL56 Alkylhalidase cmlS n=1 Tax=Micromonospora sp. AT...   117   5e-25
UniRef50_UPI0001744EC4 Putative Dehyrogenase n=1 Tax=Verrucomicr...   117   6e-25
UniRef50_B8FXK4 Electron-transferring-flavoprotein dehydrogenase...   117   7e-25
UniRef50_A8ZT45 FAD dependent oxidoreductase n=1 Tax=Desulfococc...   117   7e-25
UniRef50_C7DGR0 Geranylgeranyl reductase n=1 Tax=Candidatus Micr...   117   8e-25
UniRef50_A1HMV3 FAD dependent oxidoreductase n=1 Tax=Thermosinus...   117   8e-25
UniRef50_A2BM78 Predicted Dehydrogenase n=1 Tax=Hyperthermus but...   116   9e-25
UniRef50_Q9YAI8 Putative uncharacterized protein n=1 Tax=Aeropyr...   116   1e-24
UniRef50_Q9HLA3 FixC protein related n=2 Tax=Thermoplasma RepID=...   116   2e-24
UniRef50_Q0SF87 Possible dehydrogenase n=23 Tax=Actinomycetales ...   115   3e-24
UniRef50_D2PPR1 Geranylgeranyl reductase n=2 Tax=Actinomycetales...   114   4e-24
UniRef50_Q3A9B4 FixC protein n=1 Tax=Carboxydothermus hydrogenof...   114   5e-24
UniRef50_A1VQP8 FAD dependent oxidoreductase n=1 Tax=Polaromonas...   114   5e-24
UniRef50_B1L3D7 Monooxygenase FAD-binding n=1 Tax=Candidatus Kor...   113   1e-23
UniRef50_A0B6Y7 Geranylgeranyl reductase n=1 Tax=Methanosaeta th...   112   1e-23
UniRef50_Q2FUA4 Digeranylgeranylglycerophospholipid reductase n=...   112   2e-23
UniRef50_D1H2I2 Whole genome shotgun sequence of line PN40024, s...   112   2e-23
UniRef50_C6XUK6 FAD dependent oxidoreductase n=1 Tax=Pedobacter ...   112   2e-23
UniRef50_A2U0Z5 HI0933-like protein n=1 Tax=Polaribacter sp. MED...   112   3e-23
UniRef50_Q0SFD6 Pentachlorophenol monooxygenase n=6 Tax=Actinomy...   112   3e-23
UniRef50_A3XIL9 Putative uncharacterized protein n=1 Tax=Leeuwen...   111   3e-23
UniRef50_C1AA31 Putative oxidoreductase n=1 Tax=Gemmatimonas aur...   111   3e-23
UniRef50_A4YEK4 Geranylgeranyl reductase n=12 Tax=Sulfolobaceae ...   111   4e-23
UniRef50_Q6EVQ8 Putative FAD-dependent monooxygenase n=1 Tax=Yer...   111   5e-23
UniRef50_A5FR90 FAD dependent oxidoreductase n=5 Tax=Dehalococco...   110   6e-23
UniRef50_B4D801 Tryptophan halogenase n=1 Tax=Chthoniobacter fla...   110   6e-23
UniRef50_Q11NI5 Possible oxidoreductase n=1 Tax=Cytophaga hutchi...   110   9e-23
UniRef50_D2BAF5 Monooxygenase, FAD-binding protein n=4 Tax=Actin...   110   9e-23
UniRef50_A3DPJ1 Geranylgeranyl reductase n=2 Tax=Desulfurococcac...   110   1e-22
UniRef50_A8ABI3 Geranylgeranyl reductase n=1 Tax=Ignicoccus hosp...   109   1e-22
UniRef50_Q2NGA2 Predicted dehydrogenase n=1 Tax=Methanosphaera s...   109   2e-22
UniRef50_D1C5T7 Monooxygenase FAD-binding protein n=2 Tax=Thermo...   109   2e-22
UniRef50_C0G122 Geranylgeranyl reductase n=1 Tax=Natrialba magad...   109   2e-22
UniRef50_B3PIM4 Putative uncharacterized protein n=1 Tax=Cellvib...   109   2e-22
UniRef50_A0B730 Geranylgeranyl reductase n=1 Tax=Methanosaeta th...   108   3e-22
UniRef50_A8MD19 Monooxygenase FAD-binding n=1 Tax=Caldivirga maq...   108   3e-22
UniRef50_Q4MV03 Geranylgeranyl hydrogenase BchP, putative n=12 T...   108   3e-22
UniRef50_A4JL31 Monooxygenase, FAD-binding n=3 Tax=Burkholderia ...   108   3e-22
UniRef50_O28636 Bacteriochlorophyll synthase, 43 kDa subunit (Ch...   108   3e-22
UniRef50_Q4V217 Possible monooxygenase n=1 Tax=Bacillus cereus E...   108   3e-22
UniRef50_B4AWE1 Monooxygenase FAD-binding n=1 Tax=Cyanothece sp....   108   3e-22
UniRef50_C6VXB5 FAD dependent oxidoreductase n=1 Tax=Dyadobacter...   108   4e-22
UniRef50_C6WHE7 Monooxygenase FAD-binding n=2 Tax=Actinomycetale...   108   4e-22
UniRef50_Q0R4P7 ChlB4 n=8 Tax=Bacteria RepID=Q0R4P7_STRAT             107   4e-22
UniRef50_Q9AL91 Alkylhalidase CmlS n=3 Tax=Actinomycetales RepID...   107   5e-22
UniRef50_Q0BPD7 Dehydrogenases (Flavoproteins) n=1 Tax=Granuliba...   107   6e-22
UniRef50_D1RDY9 FAD dependent oxidoreductase domain protein n=1 ...   107   6e-22
UniRef50_A9A5W1 Dehydrogenase (Flavoprotein)-like protein n=2 Ta...   107   6e-22
UniRef50_D2C3Q7 Electron-transferring-flavoprotein dehydrogenase...   107   7e-22
UniRef50_Q1IRI6 FAD dependent oxidoreductase n=1 Tax=Candidatus ...   107   7e-22
UniRef50_B8GGY5 Geranylgeranyl reductase n=1 Tax=Methanosphaerul...   107   8e-22
UniRef50_B2A3V3 FAD dependent oxidoreductase n=2 Tax=Clostridia ...   107   8e-22
UniRef50_Q8KLM2 StaK n=1 Tax=Streptomyces toyocaensis RepID=Q8KL...   107   9e-22
UniRef50_P54805 Uncharacterized protein in nifH2 5'region n=5 Ta...   106   1e-21
UniRef50_D2RYX8 FAD dependent oxidoreductase n=5 Tax=Halobacteri...   106   1e-21
UniRef50_A8MAE2 Geranylgeranyl reductase n=6 Tax=Thermoproteacea...   105   2e-21
UniRef50_Q0Q5F4 Halogenase n=8 Tax=Actinomycetales RepID=Q0Q5F4_...   105   2e-21
UniRef50_A6C2B8 Putative uncharacterized protein n=1 Tax=Plancto...   105   3e-21
UniRef50_D2BAB1 Dehydrogenase (Flavoprotein)-like protein n=1 Ta...   105   3e-21
UniRef50_C5V9R0 FAD-linked oxidoreductase n=2 Tax=Corynebacteriu...   105   3e-21
UniRef50_A8FB69 Possible monooxygenase n=3 Tax=Bacillus RepID=A8...   104   4e-21
UniRef50_Q7USU8 Probable alkylhalidase homolog n=1 Tax=Rhodopire...   104   4e-21
UniRef50_Q1QK25 Monooxygenase, FAD-binding n=2 Tax=Nitrobacter R...   104   4e-21
UniRef50_D2S022 FAD dependent oxidoreductase n=1 Tax=Haloterrige...   104   4e-21
UniRef50_B0C5X8 Tryptophan halogenase, putative n=1 Tax=Acaryoch...   104   5e-21
UniRef50_UPI000038E09B FixC protein n=1 Tax=Ferroplasma acidarma...   104   6e-21
UniRef50_D0ZCG4 Oxidoreductase n=5 Tax=Enterobacteriaceae RepID=...   104   6e-21
UniRef50_Q1Q5X9 Hypothetical FAD oxidoreductase protein n=1 Tax=...   104   7e-21
UniRef50_A5D6E0 Dehydrogenases n=4 Tax=Bacteria RepID=A5D6E0_PELTS    104   7e-21
UniRef50_C5CNW2 Tryptophan halogenase n=13 Tax=Proteobacteria Re...   103   8e-21
UniRef50_B5I9Q2 FAD dependent oxidoreductase, putative n=2 Tax=A...   103   9e-21

>UniRef50_A1AHM5 Protein cbrA n=54 Tax=Enterobacteriaceae RepID=CBRA_ECOK1
          Length = 366

 Score =  515 bits (1325), Expect = e-144,   Method: Composition-based stats.
 Identities = 347/354 (98%), Positives = 350/354 (98%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQ GTEGFSKPCGGLLAPDAQRSFIR
Sbjct: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQHGTEGFSKPCGGLLAPDAQRSFIR 60

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD 120
           DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD
Sbjct: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD 120

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW 180
           SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW
Sbjct: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW 180

Query: 181 FAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ 240
           FAEKHPVPFYSCIFDN+IT+CYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ
Sbjct: 181 FAEKHPVPFYSCIFDNAITDCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ 240

Query: 241 FGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVL 300
           FGK VKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDS +ILRSVL
Sbjct: 241 FGKAVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSAEILRSVL 300

Query: 301 LKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAHIPQLKD 354
           LK PEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAHIPQLKD
Sbjct: 301 LKLPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAHIPQLKD 354


>UniRef50_B6ZQD5 Protein CbrA n=1 Tax=Escherichia coli O157:H7 str. TW14588
           RepID=B6ZQD5_ECO57
          Length = 374

 Score =  473 bits (1218), Expect = e-132,   Method: Composition-based stats.
 Identities = 318/328 (96%), Positives = 323/328 (98%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQ GTEGFSKPCGGLLAPDAQRSFIR
Sbjct: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQHGTEGFSKPCGGLLAPDAQRSFIR 60

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD 120
           DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD
Sbjct: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD 120

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW 180
           SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRR+LYPDHQIRKYVAIQQW
Sbjct: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRYLYPDHQIRKYVAIQQW 180

Query: 181 FAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ 240
           FAEKHPVPFYSCIFDN+IT+CYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ
Sbjct: 181 FAEKHPVPFYSCIFDNAITDCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ 240

Query: 241 FGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVL 300
           FGK VKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDS +ILRSVL
Sbjct: 241 FGKAVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSAEILRSVL 300

Query: 301 LKQPEKLNTAYWRATRKLRLKLFGKIVK 328
           LKQPEK+N AYW ATRKLRLKLFGKIVK
Sbjct: 301 LKQPEKINAAYWHATRKLRLKLFGKIVK 328


>UniRef50_D2THX1 Putative uncharacterized protein n=4 Tax=Bacteria
           RepID=D2THX1_CITRO
          Length = 380

 Score =  471 bits (1212), Expect = e-131,   Method: Composition-based stats.
 Identities = 289/354 (81%), Positives = 317/354 (89%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           MEHFDVAIIGLGPAG+ALARKL+GKMQVIALDKK QCG EGF+KPCGGLLAPDAQR+FIR
Sbjct: 1   MEHFDVAIIGLGPAGAALARKLSGKMQVIALDKKRQCGNEGFTKPCGGLLAPDAQRAFIR 60

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD 120
           DGLTLPVDVIANPQIFSVKT+DV ASL RNYQRSYININRHAFDLW+KSLIP  V VYHD
Sbjct: 61  DGLTLPVDVIANPQIFSVKTIDVEASLERNYQRSYININRHAFDLWLKSLIPDDVRVYHD 120

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW 180
           SLCRKIWRE+DKWH+IFRADG EQ +T RYLVGADGANS+VRR+LYP HQIRKYVAIQQW
Sbjct: 121 SLCRKIWREEDKWHIIFRADGQEQKVTTRYLVGADGANSLVRRYLYPQHQIRKYVAIQQW 180

Query: 181 FAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ 240
           FAE HPVPFYSCIFDN+IT+CYSWSISKDGYFIFGGAYPMKDGQ RF  LK KM AFQF+
Sbjct: 181 FAESHPVPFYSCIFDNAITDCYSWSISKDGYFIFGGAYPMKDGQARFEALKAKMEAFQFR 240

Query: 241 FGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVL 300
           FG  +KSEKCTVLFPSRW+DFVCGKDNAFLIGEAAGFISASSLEGISYALDS D L +VL
Sbjct: 241 FGNPLKSEKCTVLFPSRWKDFVCGKDNAFLIGEAAGFISASSLEGISYALDSADRLNAVL 300

Query: 301 LKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAHIPQLKD 354
            +     N+AY + TR+LR+KL+GKI+KSR LT+   RK +M+SGVAHIP  +D
Sbjct: 301 TRHAADKNSAYRKVTRQLRIKLYGKILKSRILTSALTRKRVMQSGVAHIPLAQD 354


>UniRef50_C3KYD3 CbrA protein n=14 Tax=Bacteria RepID=C3KYD3_CLOB6
          Length = 364

 Score =  409 bits (1050), Expect = e-112,   Method: Composition-based stats.
 Identities = 185/349 (53%), Positives = 248/349 (71%), Gaps = 1/349 (0%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           +  +D+AIIGLGP+GS LA+ L+ K +VIA+DKK+    +GF KPCGGLL+ DAQ++  +
Sbjct: 6   ISTYDIAIIGLGPSGSVLAQLLSKKHKVIAIDKKNSI-EKGFKKPCGGLLSSDAQKALAK 64

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD 120
             +TLP DV+ +PQIF+VKT+++  +L R YQR YIN++RH FDLW+KSLIP  VEVY +
Sbjct: 65  LDITLPKDVMVDPQIFAVKTIELKNALIRYYQRFYINLDRHKFDLWLKSLIPNHVEVYSN 124

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW 180
           S C  + +  + + V F   G +Q I  +YLVGADGANS+VRR LYP  +IR Y++IQQW
Sbjct: 125 SYCSSVEKIPEGYRVTFYEKGVKQVIITKYLVGADGANSLVRRSLYPKKKIRTYMSIQQW 184

Query: 181 FAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ 240
           F+E H  PFYSCIFD   T+C SWSISKD  FIFGGA+P+ + + RF   K+K+    F+
Sbjct: 185 FSETHDNPFYSCIFDLENTDCCSWSISKDNKFIFGGAFPIHNSRKRFENQKKKLEKIGFR 244

Query: 241 FGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVL 300
           FGK +K+E C VL PS + DF CGK+NAFL+GEAAGFIS SSLEGIS A++S  +L  VL
Sbjct: 245 FGKPIKTEACMVLRPSAFYDFCCGKENAFLVGEAAGFISPSSLEGISSAINSARVLSEVL 304

Query: 301 LKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAHI 349
               +  N  YW  T  +RLK+F K++K   +  P LRK +++SG+  I
Sbjct: 305 NTHSKDPNKKYWLKTFNIRLKIFLKLLKCPFMYNPFLRKLVLKSGLKSI 353


>UniRef50_UPI00019786F4 putative oxidoreductase n=1 Tax=Helicobacter cinaedi CCUG 18818
           RepID=UPI00019786F4
          Length = 389

 Score =  347 bits (890), Expect = 3e-94,   Method: Composition-based stats.
 Identities = 157/367 (42%), Positives = 218/367 (59%), Gaps = 19/367 (5%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGT---EGFSKPCGGLLAPDAQRS 57
           +  FD+AIIGLG AGS LA  L   ++VIA+DKK   G    E F KPCGGLL+   Q++
Sbjct: 14  LGEFDIAIIGLGVAGSNLASLLQSHLKVIAIDKKDSSGDCFDESFHKPCGGLLSEGGQKA 73

Query: 58  FIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEV 117
           F   GL LP  ++  PQIF++ T+D         Q+ YIN+ RHAFDLW KS IP+ +  
Sbjct: 74  FATQGLNLPTRLLVEPQIFAINTIDYGYPHASYIQKGYINMERHAFDLWQKSRIPSHIST 133

Query: 118 YHDSLCRKIWREDDKWHVIF--RADGWEQHI------TARYLVGADGANSMVRRHLYPDH 169
           +H +  + + + ++  + +   R D     I       A+ ++GADGA S +RR+LYP  
Sbjct: 134 FHKAYFKSLKQGENGIYTLHFKRQDSKNAKISQDFTCKAKIIIGADGAKSHLRRYLYPQL 193

Query: 170 QIRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTT 229
           + +  V IQ+W+ E H  P  SC+FD  +T  YSWS+SK+GYFIFGGAYP  + Q RF T
Sbjct: 194 KTKSLVCIQEWYKE-HNAPMLSCVFDKELTPSYSWSMSKNGYFIFGGAYPHANCQERFAT 252

Query: 230 LKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYA 289
             E++    F FGK +K E C VL P+R +DFV G    FLIGEAAGFI+AS+LEGIS A
Sbjct: 253 QIERLRTLGFIFGKPLKKEACLVLQPTRLKDFVLGHSGVFLIGEAAGFINASTLEGISGA 312

Query: 290 LDSTDILRSVLL------KQPEKLNTAYWRATRKLRLK-LFGKIVKSRCLTAPALRKWIM 342
           ++S+ IL  +L        +   L+ AY    R L +K LF   V+   +  P +R+ I+
Sbjct: 313 MNSSRILAHILNACDMNVSRTSTLHRAYRAKARMLIVKTLFRHYVRYPFMFVPCIRRLIL 372

Query: 343 RSGVAHI 349
           R G+  +
Sbjct: 373 RFGLLRL 379


>UniRef50_Q7VFG9 Putative uncharacterized protein n=1 Tax=Helicobacter hepaticus
           RepID=Q7VFG9_HELHP
          Length = 384

 Score =  345 bits (885), Expect = 1e-93,   Method: Composition-based stats.
 Identities = 160/371 (43%), Positives = 221/371 (59%), Gaps = 23/371 (6%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKH---QCGTEGFSKPCGGLLAPDAQRS 57
           +  +D+AIIGLG AGS LA  L   ++VIA+DKK     C  E F KPCGGLL+  AQ++
Sbjct: 5   LGEYDIAIIGLGVAGSNLAALLNLHLKVIAVDKKDIQGHCNDEHFHKPCGGLLSQGAQKA 64

Query: 58  FIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEV 117
           F   GL LP  ++ANPQIF++ T+D         Q++YIN+ RH FDLW+KSLIP  +  
Sbjct: 65  FAMQGLNLPNTLLANPQIFAINTIDWHYPYASYIQKAYINMERHRFDLWLKSLIPPHIHT 124

Query: 118 YHDSLCRKIWREDDKWHVIFRADGWEQHIT----ARYLVGADGANSMVRRHLYPDHQIRK 173
           +H +  ++I ++   + + F  +   QHI+    AR ++GADGA S +RR LYP  +I  
Sbjct: 125 FHKAYFKRIEQKQGFYTIYFTQEQDSQHISYHCNARLVIGADGAKSHIRRWLYPQLKIPS 184

Query: 174 YVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEK 233
            V IQ+WF E       SCIFD  ++  YSWS+SKD YFIFGGAYP K  +  F T KE+
Sbjct: 185 LVCIQEWFKESTN-SMLSCIFDKELSPSYSWSMSKDEYFIFGGAYPHKQCKRAFATQKER 243

Query: 234 MSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDST 293
           +    F FG+  K E C VL P+RW+DFV G    FL+GEAAGFI+AS+LEGIS A++S+
Sbjct: 244 LKNLGFIFGQPFKREACLVLTPTRWRDFVQGHSGVFLVGEAAGFINASTLEGISGAMNSS 303

Query: 294 DILRSVLLKQP--------------EKLNTAYWRATRKLRLK-LFGKIVKSRCLTAPALR 338
            IL  +L  +               + L+  Y + TR L  K L    V+   +  P  R
Sbjct: 304 RILSEILNNEEFNALSRNKDIALWYKLLHRTYTKRTRFLVCKTLLRHYVRYPFMFIPLFR 363

Query: 339 KWIMRSGVAHI 349
           ++I+R G+  +
Sbjct: 364 RFILRFGILRV 374


>UniRef50_B8FUH4 FAD dependent oxidoreductase n=3 Tax=Clostridiales
           RepID=B8FUH4_DESHD
          Length = 356

 Score =  335 bits (858), Expect = 2e-90,   Method: Composition-based stats.
 Identities = 132/351 (37%), Positives = 204/351 (58%), Gaps = 5/351 (1%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFS---KPCGGLLAPDAQRSFIR 60
           +DV IIG GPAGS+LAR +  K +V+ +DK+        +   K CGGLLAPDAQ+   +
Sbjct: 2   YDVLIIGAGPAGSSLARLIGDKYKVLLIDKRDLANENPHNLAGKCCGGLLAPDAQKMIAK 61

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD 120
            GL +P D++ NPQ+F+V+T+D+  +L R YQR Y+N++R  FD W+ S++P  V+   +
Sbjct: 62  LGLGIPKDILVNPQLFAVRTIDLTNNLERLYQRFYLNMDREKFDRWLVSILPKKVDKKFN 121

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPD-HQIRKYVAIQQ 179
           ++ +        + V +  +G E     R ++GADGA S +RR L  D +   KY+AIQ+
Sbjct: 122 AVFKDFVEIPGGYEVKYIHNGQEISAKTRVIIGADGAFSKLRRFLNQDINGPEKYIAIQE 181

Query: 180 WFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAY-PMKDGQTRFTTLKEKMSAFQ 238
           W+   H VP+++ IFD  I++ YSW I K+ Y + G A  P +  + ++  LK K++   
Sbjct: 182 WYECPHHVPYFTAIFDEEISDFYSWIIPKENYLLLGSALKPKEKAREKYELLKTKLTQRG 241

Query: 239 FQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRS 298
           F F   +++E   +  P +   F  G+D+  L+GEAAG IS SS EGISYAL S+  L  
Sbjct: 242 FNFDNKIRTEGAYLYRPKKVSQFYAGRDSIALVGEAAGGISPSSAEGISYALKSSAYLAQ 301

Query: 299 VLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAHI 349
            L +  +     Y    + ++L L  K +KS  +  P LR+  M+SG+  I
Sbjct: 302 SLEEGIDGFLDRYKLKVKGIKLNLLLKNLKSPAMYNPLLRQLAMKSGLQSI 352


>UniRef50_C6JQS4 FAD dependent oxidoreductase n=1 Tax=Fusobacterium varium ATCC
           27725 RepID=C6JQS4_FUSVA
          Length = 355

 Score =  293 bits (751), Expect = 5e-78,   Method: Composition-based stats.
 Identities = 114/349 (32%), Positives = 188/349 (53%), Gaps = 6/349 (1%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKH-QCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +D+ +IG GPAGS  ++ +  K +V+ LD++  +       K CGGLLA +AQ +    G
Sbjct: 3   YDIVVIGGGPAGSVFSKFINSKYKVLLLDRRDYEDENNKIIKCCGGLLAHEAQAALSGLG 62

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSL 122
            +L  D++ +PQ+F+V+ +D   +L + Y ++Y+N +R  FD ++ S   + VE+   +L
Sbjct: 63  YSLSKDILVSPQVFNVQVIDYDNNLKKKYYKNYLNFDREKFDNYLLSQKASHVELIKGAL 122

Query: 123 CRKI-WREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWF 181
                  E+  + VI+R     + +  + +V A+GANS++R++L  +     Y+AIQ+ +
Sbjct: 123 FIDYSEDENGIYTVIYRIGMDIKKVKTKMIVSAEGANSLIRKNL-DNKSKNDYIAIQRVY 181

Query: 182 AEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQ-TRFTTLKEKMSAFQFQ 240
             K    ++  IFD +I N YSW + K    I G       G   +F  L+E++ +    
Sbjct: 182 KMKKDFSYHMAIFDKNINNYYSWLVPKGNELILGTILKKGKGSWDKFHQLEERVKSEGID 241

Query: 241 FGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVL 300
               ++ E   +  P +W ++   KD   LIGEAAG ISASS EGISYAL S   L   +
Sbjct: 242 INDIIRDEGTFIRVP-KWNEYFMAKDRIALIGEAAGLISASSSEGISYALISGYYLADSI 300

Query: 301 LKQPEKLN-TAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAH 348
            K+  K     Y + T  +R+KL  KI+K + +    +RK+I+ SGV  
Sbjct: 301 NKKGIKSGIIEYCKRTESIRMKLNLKILKGKLMYNSFIRKFIIMSGVFS 349


>UniRef50_Q1IMS5 Geranylgeranyl reductase n=1 Tax=Candidatus Koribacter versatilis
           Ellin345 RepID=Q1IMS5_ACIBL
          Length = 379

 Score =  250 bits (637), Expect = 8e-65,   Method: Composition-based stats.
 Identities = 82/357 (22%), Positives = 128/357 (35%), Gaps = 27/357 (7%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           M H    I+G GP+G+A A  LA     + L  + +       KPCGG L     ++   
Sbjct: 1   MGHQSFIIVGAGPSGTAAAYDLAKAGHSVLLLDRSE---FPRVKPCGGGLTVKTLKALRY 57

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD 120
                PV  I    +     +     L   +   ++ +     D  ++  + A       
Sbjct: 58  SV--TPVVRIVAKGLQVTNNLAEPIELRGKHPICFMTVRAEFDDFCLRQTLEAGARFQKI 115

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW 180
           S    +    D  HV+ R    E H  A YL+GADGANS VR  L      R+ +A++  
Sbjct: 116 SEITGVEEFPD--HVVLRTRDGEFH--AEYLLGADGANSKVRLLLGAQPWFRRAIAVEAH 171

Query: 181 FAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSA--FQ 238
                        F   +   Y+WS  K  +   G    +         L   + A   +
Sbjct: 172 APVHKNAKAMEIDF-GVVPRGYAWSFHKGDHLNVG----LCTESAEVVKLSRDLLANYLK 226

Query: 239 FQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRS 298
            +FG    S             +       FL+G+AAG     S EGI  A+ S     S
Sbjct: 227 RKFGSDEYSHFVGHYLGIGGMRYEPKHKRIFLVGDAAGMTDPLSGEGIYNAIKSGQAAAS 286

Query: 299 VLLKQPEKLNTAYWRATRKLR----------LKLFGKIVKS-RCLTAPALRKWIMRS 344
            LL+  E  + +Y +A   +R           K +G +      L  P ++K I++ 
Sbjct: 287 ALLQNSEAPHVSYAQALADVRDDLEFCERAIGKFYGHLNAGFAMLKVPGMKKSILKG 343


>UniRef50_D1RCG6 Geranylgeranyl reductase family protein n=1 Tax=Legionella
           longbeachae D-4968 RepID=D1RCG6_LEGLO
          Length = 503

 Score =  236 bits (603), Expect = 6e-61,   Method: Composition-based stats.
 Identities = 82/324 (25%), Positives = 125/324 (38%), Gaps = 23/324 (7%)

Query: 5   DVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           DV I G GP+G+  A  LA   + + L   H        K CG  ++P + +  +  G+T
Sbjct: 27  DVLIAGAGPSGAICAYYLAQAGKKVILIDSHS---FPRDKVCGDFVSPVSLKELMTLGIT 83

Query: 65  -LPVDVIANPQIFSVKTVDVAASLTRNYQ--RSYIN----INRHAFDLWMKSLI-PASVE 116
            LP     N    +   VD    +T N    + ++N    I R   D W+ +      V 
Sbjct: 84  DLPEFKATNMITEATVYVDGQKLITDNIPQIKDFVNYGRVIPRVLLDTWIVNAAKQQGVN 143

Query: 117 VYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKY-- 174
           V  D      +  +    V     G ++    + LVGADG+NS V R L       K+  
Sbjct: 144 VITDCKLVNYFVNEQDVRVECEQHGKKRRFLIKILVGADGSNSTVARILQGKKPNPKHKI 203

Query: 175 VAIQQWFAEKHPVPFYSCIFDNSIT-NCYSWSISKDGY-FIFGGAYPMKDGQTRFTTLKE 232
           VA++ +    + +P  + +F    T   Y W           G    +K      T LK 
Sbjct: 204 VAVRAYCENINCIPHQATLFFTRNTFPGYFWFFPTSSTTANVGIGMVLKTFPKNETNLKA 263

Query: 233 KMSAF--QFQFGKTVKSEKCTVLFPSRWQ------DFVCGKDNAFLIGEAAGFISASSLE 284
            +        F KT  S+   +   + W         +  KD   L G+AAGFI+  + E
Sbjct: 264 MLLEMIGNDPFFKTKISQGMQITKIAGWPLSCYDPSTINVKDRVLLTGDAAGFINPFTGE 323

Query: 285 GISYALDSTDILRSVLLKQPEKLN 308
           GI YAL S  +    ++   E  N
Sbjct: 324 GIQYALQSGRLAAETIIGSFETEN 347


>UniRef50_B9L6H5 Geranylgeranyl hydrogenase n=2 Tax=Nautiliaceae RepID=B9L6H5_NAUPA
          Length = 324

 Score =  235 bits (598), Expect = 2e-60,   Method: Composition-based stats.
 Identities = 80/346 (23%), Positives = 131/346 (37%), Gaps = 48/346 (13%)

Query: 6   VAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTL 65
           + IIG GPAGS  ARKLA    V  +  K       F KPCGG +   A + F      +
Sbjct: 3   IVIIGGGPAGSTAARKLAPFYHVTLIQDKLD-----FDKPCGGGIKTKAFKEF-----DI 52

Query: 66  PVDVIAN---PQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSL 122
           P  +I +     I   K   V   L     ++   + R  FD  ++ L   +        
Sbjct: 53  PNKLIKHSLDHVIMKYKNTTVKVDLNG---KNLSIVKRDEFDKKLRDLAQQAGAKIIYGR 109

Query: 123 CRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFA 182
            + +         I + D    ++    L+ ADG NS VR+ L       K  A    +A
Sbjct: 110 FKTVK----NNKAIIKTDNSILNLDYDILIAADGVNSTVRKALNLP----KIPATITHYA 161

Query: 183 EKHPVPFYSCIFDNSI---TNCYSWSISKDGYFIFGGAYPMK-DGQTRFTTLKEKMSAFQ 238
                   +C F          Y+W+   +     G       +   R+  +K K   ++
Sbjct: 162 RIDQYKVQTCEFFFDFDIGGEYYAWAFPHENLTHIGTVSRGNFENLCRYLNVKAKPKGYK 221

Query: 239 FQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRS 298
                           P+  ++ +  K+N + +G+AAG +   S EGI YA+ S D+L +
Sbjct: 222 ---------------IPTWQENIIIQKNNVYFVGDAAGQVMPLSFEGIYYAIKSADLLAN 266

Query: 299 VLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRS 344
            +L+     N  Y     K   K F  + K   L    +R +++++
Sbjct: 267 CILE-----NKNYPNEWNKRFFKEFSLMKKLEALNKTFIRGFVVKA 307


>UniRef50_A6QA88 Geranylgeranyl hydrogenase n=1 Tax=Sulfurovum sp. NBC37-1
           RepID=A6QA88_SULNB
          Length = 361

 Score =  231 bits (589), Expect = 2e-59,   Method: Composition-based stats.
 Identities = 82/333 (24%), Positives = 139/333 (41%), Gaps = 28/333 (8%)

Query: 5   DVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           D+ IIG GPAGS LAR LA   +   L +++      F KPCGG +  DA   F  D   
Sbjct: 5   DILIIGGGPAGSTLARYLAEAGKETILVQRN----FNFRKPCGGGIRLDAFDEFDIDREL 60

Query: 65  LPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLCR 124
           +  +V +   +F  K V+V  S     Q     ++R  FD ++++    +     ++   
Sbjct: 61  IRKEVNSIALVFGTKRVEVDIS-----QMPLGIVDRVEFDTYLRNRAEDTGATLLEASFV 115

Query: 125 KIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEK 184
            +   D    V    DG  + I A YLVGADG NS VR+ +  D       +    +A+ 
Sbjct: 116 DVEVCDGYIIVTIEQDGVYKKIHAGYLVGADGVNSKVRKCINGDR----VPSAMTRYADL 171

Query: 185 HPVPFYSCIF---DNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQF 241
               + +C F        + Y+W+         G      D +T      +++       
Sbjct: 172 AHTAYKTCEFHFGSKVAGSYYAWAFPHTNGSNIGTLA--GDDETHIQHFMKQL------- 222

Query: 242 GKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLL 301
               +  K       ++++ V  KD  F +G++A  +   + EGI YA+ S  +L +VL 
Sbjct: 223 -DVKEKVKLLGYRIPQFENPVFYKDRVFFVGDSASQVLPFTYEGIYYAMASAHLLSAVLT 281

Query: 302 KQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTA 334
           +Q +   + Y +      L+ F  + + + L  
Sbjct: 282 EQADP--SEYEKRWNDTYLQKFTTLQRLQKLFL 312


>UniRef50_Q1PX22 Putative uncharacterized protein n=1 Tax=Candidatus Kuenenia
           stuttgartiensis RepID=Q1PX22_9BACT
          Length = 351

 Score =  227 bits (578), Expect = 5e-58,   Method: Composition-based stats.
 Identities = 87/340 (25%), Positives = 143/340 (42%), Gaps = 34/340 (10%)

Query: 4   FDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +D  ++G GP+G+A A++L G  ++V+ L+KK         K C G++   +Q    R  
Sbjct: 5   YDAVVVGSGPSGAAAAKRLTGEGLRVLVLEKKKL----PRYKICSGIIFKKSQEITERYF 60

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLT-------RNYQRSYININRHAFDLWMKSLIPASV 115
             +P  V   P++  +K V   + L                N+ R  +D W+   I  S 
Sbjct: 61  GRIPDAVYVQPKL--LKGVRFWSDLGNYSDWPFSKDSEGAPNVWRSEYDYWL---ISNSG 115

Query: 116 EVYHDSLCRKIWREDDKWHVIFRADGWEQHIT---ARYLVGADGANSMVRRHLYP--DHQ 170
               D    K +  +    V+   D  E  I     RYL+ A+G+ S +R  L P  +  
Sbjct: 116 AEVMDCAVFKGFETEGNAVVVHYYDARENKIRQAKCRYLISAEGSVSCIRAMLSPAFERN 175

Query: 171 IRKYVAIQQWFAEKHPVP--FYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFT 228
           ++ ++A Q ++  +  +   FY    D      Y+W   KD   +FG +  ++ G     
Sbjct: 176 VKWFIAYQNYYEGQSSLDPYFYHGFLDQKYGEVYAWFSVKDDLQVFGTS--VRKGAKILP 233

Query: 229 TLKEKMSAFQFQFGKT----VKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLE 284
            L       + + G      V+   C         +F  GK N  L+GEAAGF++A   E
Sbjct: 234 CLNAFHEMLEKEHGLALKKLVRKTSCLGNTMCASGNFYLGKGNILLVGEAAGFLNAF-GE 292

Query: 285 GISYALDSTDILRSVL---LKQPEKLNTAYWRATRKLRLK 321
           GIS AL S       +   +K  E + +AY   T+K R +
Sbjct: 293 GISCALSSGLFAAEAICACIKSGEDVISAYTELTKKERRQ 332


>UniRef50_B5W6L5 Geranylgeranyl reductase n=2 Tax=Arthrospira RepID=B5W6L5_SPIMA
          Length = 378

 Score =  225 bits (573), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 75/303 (24%), Positives = 112/303 (36%), Gaps = 15/303 (4%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           FD  I+G GPAG+  A  LA K   I +  K         KPCGG ++P  Q  F  D  
Sbjct: 3   FDCIIVGSGPAGATAAYHLAKKGHSILVIDKAIL---PRYKPCGGGVSPIVQDWFDFDFS 59

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLW-MKSLIPASVEVYHDSL 122
                          K+  +   L  N       + R  FD + +K  I     V  ++ 
Sbjct: 60  PAISLKTVMVYYTWNKSEPIEVELKIN---PIWMVRREVFDYFILKQAISKGATVRDNTE 116

Query: 123 CRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYV-AIQQWF 181
              I  + D+W V       E   T RYL+GADGA   + + L    Q +    A++   
Sbjct: 117 VLGIEFQSDRWLVKT----PEDTYTGRYLIGADGAKGPLAKWLGFTKQKKLVAGALELEI 172

Query: 182 AEKHPVPFYSCIFDNSITNCYSWSISK-DGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ 240
               PV   +      + + Y W+  K DGY +  GA+  +     F  + E  + F F 
Sbjct: 173 PTSKPVDMKTYFEFGLVNSGYGWNFPKADGYSLGAGAFSKQRKAQNFKRILEDYATF-FN 231

Query: 241 FGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVL 300
                 + +C                NA L GEAA  +   + EGI  ++ S       +
Sbjct: 232 LNLD-NATECGHPISLWDGQQKLHTQNAVLAGEAACVVDPFTAEGIRPSIFSGLKAAEAI 290

Query: 301 LKQ 303
            + 
Sbjct: 291 NQA 293


>UniRef50_Q649G8 Geranylgeranyl reductase n=3 Tax=environmental samples
           RepID=Q649G8_9ARCH
          Length = 385

 Score =  224 bits (570), Expect = 4e-57,   Method: Composition-based stats.
 Identities = 69/350 (19%), Positives = 136/350 (38%), Gaps = 25/350 (7%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M+ +DV +IG GP+G+  ++  AG  ++ +  +K+         K CGG ++  A     
Sbjct: 1   MQQYDVIVIGAGPSGAIASKTCAGNGLKTLLFEKEGI----PRLKLCGGAVSTSALSDLD 56

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKS-LIPASVEVY 118
                +  D+I      +           +   R  I ++R  FD ++ S  + A V ++
Sbjct: 57  ---FGIEKDLIERECYGARVHFKTHQIEVKRKSRLAILVSRDKFDAYLVSKAVDAGVALH 113

Query: 119 HDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHL---YPDHQIRKYV 175
                  I  E  +  V    +  ++   A+ ++GADG NS+V +++   Y   ++   +
Sbjct: 114 EAEKATSIKPEQSRIVV----ETNKEKYNAKVVIGADGVNSIVSKYVRDSYKPDELGFCI 169

Query: 176 AIQQWFAEKHPVPFYSCIFD---NSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKE 232
           A +   + +    +     D         Y W   K+ +F  G    +          ++
Sbjct: 170 AAEIPASNEEVNEYIENAIDIHYGITNFGYGWVFPKEKHFSVG----LCGILPSMKNSRD 225

Query: 233 KMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDS 292
              AF  + G +        L P+   +     D   L+G+AAGF+     EGI YA  S
Sbjct: 226 IFIAFIKKLGFSTDVNSHAHLIPAGGYEREVCSDRIMLVGDAAGFVDPYQGEGIKYAFIS 285

Query: 293 TDILRS--VLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKW 340
             +     V   + ++ + +     ++    LFG+ +K        + K+
Sbjct: 286 AKLAAERVVESYENDEFSKSALDTYKRTCYSLFGENLKYSLRLTRLMYKY 335


>UniRef50_Q8DGN7 Tlr2279 protein n=5 Tax=Cyanobacteria RepID=Q8DGN7_THEEB
          Length = 375

 Score =  215 bits (548), Expect = 2e-54,   Method: Composition-based stats.
 Identities = 68/300 (22%), Positives = 107/300 (35%), Gaps = 18/300 (6%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           +D  ++G GPAG + A  LA + + + + +K         KPC G ++P   + F  D  
Sbjct: 5   YDCIVVGSGPAGGSAAYHLARRQRSVLVLEKAAL---PRQKPCTGGISPVIGQWFDVDFQ 61

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD-SL 122
               D     + +S K  D A     +       + R  FD ++         V  D + 
Sbjct: 62  PAIADTTRTVR-YSWKFKD-AVEAELSIPEPIWIVERTVFDHYLLQQAQQKGAVVADQTE 119

Query: 123 CRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFA 182
              I  + D W V             RYL+ ADGANS + R L    ++ +  A+     
Sbjct: 120 VTGITFQKDHWQVHTATT----TYGGRYLIAADGANSQMARWLGFKPKVGRTAAVMT--- 172

Query: 183 EKHPVPFYSCIF-DNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFT-TLKEKMSAFQFQ 240
             +P    +  F    + N Y WS  K      G A      +  +   L++  +  Q Q
Sbjct: 173 VPNPRGDRAAHFEFGLVKNGYLWSFPKGDQRTVGVAVVRGSDRPNWEPILQQYCAVHQLQ 232

Query: 241 FGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVL 300
                       +             +A L GEAAG +   S EG+  AL S       +
Sbjct: 233 LADCPIQYHPLCI---WEGQQPLHTHHALLAGEAAGLVDPFSAEGVRPALYSGMRAAEAI 289


>UniRef50_P96800 Uncharacterized protein Mbar_A1602 n=1 Tax=Methanosarcina barkeri
           str. Fusaro RepID=Y1602_METBF
          Length = 387

 Score =  212 bits (540), Expect = 1e-53,   Method: Composition-based stats.
 Identities = 77/313 (24%), Positives = 126/313 (40%), Gaps = 30/313 (9%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M+ +DV IIG GPAGS  A  LA  K+ V+ +DK     +    KPC G L   A  SF 
Sbjct: 4   MKKYDVVIIGAGPAGSYAAYMLAKSKINVLVIDKY----SFPRYKPCAGGLTAKAFNSFD 59

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVY 118
              ++  V    N  + S K   +  +++ N     + I R  FD ++ K  + +     
Sbjct: 60  -FPISKEVKYSTNSIVTSYKN-QIFHNISGNKTLVKM-IERKEFDDFLIKKAVDSGATFL 116

Query: 119 HDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLY-PDHQIRKYVAI 177
                 +I  E+ ++ +        +     YL+GADG N +V R     +  +  +   
Sbjct: 117 DGMKVTEITWENAEFSIKT----DSEFFRCNYLIGADGTNGIVNRTFNIVERDLYGFAVE 172

Query: 178 QQWFAEKHPVPFYSCIFD-NSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSA 236
                 +  +  ++  FD  ++ N Y W   KD Y   G     +        +++ +  
Sbjct: 173 INCPVSRDNIGKFNMTFDFGTVPNGYLWIFPKDEYVCVGAYTTNRK----MKNIQKYLLD 228

Query: 237 FQFQFGKTVKSEKCTVLFP------SRWQDFVCGKDNAFLIGEAAGFISASSLEGISYAL 290
           +  + G   +SEK             +  DF C      L+G+AAGF    + EGI YA+
Sbjct: 229 YIEKLGLVPESEKLKGHIIPYYGINYKQPDFPC-----VLVGDAAGFGEYWTGEGIYYAV 283

Query: 291 DSTDILRSVLLKQ 303
            S  I   V+   
Sbjct: 284 KSGTIAAEVISSS 296


>UniRef50_P26172 Geranylgeranyl diphosphate reductase n=34 Tax=Bacteria
           RepID=BCHP_RHOCA
          Length = 391

 Score =  212 bits (540), Expect = 2e-53,   Method: Composition-based stats.
 Identities = 84/338 (24%), Positives = 134/338 (39%), Gaps = 29/338 (8%)

Query: 3   HFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSF-IR 60
            +D  ++G GPAGS  A  +A   ++V  LD+       G  KPCGG + P   R F I 
Sbjct: 2   KYDAFVVGGGPAGSTAAWDMARAGLKVALLDR------AGRIKPCGGAIPPRLIRDFDIP 55

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYIN-INRHAFDLWMKSLIPASVEVYH 119
           D L +     A     + + VD+        +  ++  ++R  +D W++     +     
Sbjct: 56  DHLLVAKITSARMISPTGRFVDIP------IENGFVGMVDREDYDEWLRERAGKAGAERL 109

Query: 120 DSLCRKIWREDDKWHVIFR--ADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAI 177
                +I R+  K  V++R    G E     R ++GADGANS VR  + P  +I    A 
Sbjct: 110 TGTWLRIERDSGKTVVVWRDKVTGEEMKAETRVVIGADGANSQVRNEV-PATKIPLVFAY 168

Query: 178 QQWFAEKHPVPFYS-----CIFDNSI-TNCYSWSISKDGYFIFGGAYPMKDGQTR-FTTL 230
            +       V  Y        +D  I  + Y W          G    + D   +  TTL
Sbjct: 169 HEIIKAPTTVANYDPTRCDVYYDGRISPDFYGWVFPHGKTASIGMGTELPDVSLKDCTTL 228

Query: 231 KEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYAL 290
             +MS    +  +T++ E   +  P +  D      +  L G+AAG ++ SS EGI YA 
Sbjct: 229 LRQMSGLDKE--ETIRKEGAPI--PLQPLDVWDNGKDVVLSGDAAGVVAPSSGEGIYYAH 284

Query: 291 DSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVK 328
                     +   +    A  +  R   +K  G + K
Sbjct: 285 AGGRYAAEAAMAFLKSGKPADLKLARAGFMKEHGTVFK 322


>UniRef50_A6CDB5 Geranylgeranyl reductase n=1 Tax=Planctomyces maris DSM 8797
           RepID=A6CDB5_9PLAN
          Length = 375

 Score =  210 bits (534), Expect = 8e-53,   Method: Composition-based stats.
 Identities = 77/338 (22%), Positives = 123/338 (36%), Gaps = 31/338 (9%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           E  DV I+G GP GS+ A  L    + V+ LD+     T    K C G + P        
Sbjct: 4   ESCDVLIVGGGPGGSSCAWGLQDSGLDVLILDQ----ATFPRDKVCAGWITPAVTDLLNL 59

Query: 61  DGLTLPVDVIANPQI-FSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYH 119
           D        +  P   F    +  AA  T   Q     I R  FD ++ S          
Sbjct: 60  DLSDYQKSHVLQPITRFRTGIIGGAAVQTEFTQTVSYGIRRCEFDEYLLSRC--GARTRL 117

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAI-Q 178
               + + R ++ W V          + A+ +VGA G    V R L P+ +    V + Q
Sbjct: 118 GEKFQSLERTENGWLV-------NGSLQAKVIVGAGGHFCPVARWLNPEKRSEHSVVLAQ 170

Query: 179 QWFAEKHPVPFYSC--------IFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTL 230
           +   +  P     C        ++ +     Y+W   KDGY   G     ++G+ + +  
Sbjct: 171 ETEFQLTPEQLKVCRVQPERPELYFSPDLRGYAWCFLKDGYLNVGIG---REGEKQLSAA 227

Query: 231 KEKMSAFQFQFGKTVK----SEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGI 286
           +++   F    G+  +      K         +      D   LIG+AAG  S  S EGI
Sbjct: 228 RDEFIQFLDLEGRVPRGILGKFKGHAYRLYGLEKRSVVDDRILLIGDAAGLASPQSGEGI 287

Query: 287 SYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFG 324
             A++S  +   VL +     +  + +   +  L  FG
Sbjct: 288 RPAVESGLMAADVLQQCQSSYHIQHLQNYEQKILDRFG 325


>UniRef50_B3ECC8 Geranylgeranyl reductase n=3 Tax=Chlorobium RepID=B3ECC8_CHLL2
          Length = 389

 Score =  209 bits (532), Expect = 1e-52,   Method: Composition-based stats.
 Identities = 82/351 (23%), Positives = 131/351 (37%), Gaps = 45/351 (12%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
             +   ++G GP+GS+ A   A   M V  +DK          K CGGLL    ++ F+ 
Sbjct: 3   NFYTCLVVGAGPSGSSAAYTFAKNGMDVCVIDK----AIFPRDKLCGGLLTRRTKQCFLD 58

Query: 61  DGLTLPVDVI---ANPQIFSVKTVDVAASLTRNYQRSYININRHAFDL-WMKSLIPASVE 116
              T   D+    +N  +F  K   + A    NY   +   NR  FD   ++ ++    +
Sbjct: 59  VFGTGWEDIHECWSNGALFFHKGQMINAIE--NYGELFF-CNRRTFDHALLEKVMAKGAD 115

Query: 117 VYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVA 176
           V        +   D    +     G E  I  RYL+GADG NS+V R +      R   A
Sbjct: 116 VVLGDRVEGV---DTTLKMCRLRSGRE--IRYRYLIGADGVNSVVARAVTSKGFDRNRYA 170

Query: 177 IQQWFAEKHPVPFYSC---------IFDNSITNCYSWSISKDGYFIFG-GAYPMKDGQTR 226
               FA +   P   C         I+   +   Y W   K   +  G GA   K+G   
Sbjct: 171 ----FAVQAETPDVICRQNDMILPEIYFGEVDWGYGWVFPKKNSYSVGIGALCQKNG--- 223

Query: 227 FTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDN-----AFLIGEAAGFISAS 281
                  ++    +F     S+ C+V     +  F     N       ++G+AAG +   
Sbjct: 224 ------DVAGKFREFYLARNSQPCSVTLKGHYIPFGNFSRNAVAKDIVIVGDAAGLVDPI 277

Query: 282 SLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCL 332
           + EGI+YA++S       ++      N        K   K+  +I ++  L
Sbjct: 278 TGEGIAYAIESGQYAAQAVILASSNKNITLADEYEKYYSKITQEIDRANML 328


>UniRef50_Q3A1Y0 Flavoprotein-containing dehydrogenase n=1 Tax=Pelobacter
           carbinolicus DSM 2380 RepID=Q3A1Y0_PELCD
          Length = 414

 Score =  208 bits (529), Expect = 3e-52,   Method: Composition-based stats.
 Identities = 84/371 (22%), Positives = 132/371 (35%), Gaps = 25/371 (6%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           ++ +DV I G GPAGS  A  LA     + L  +        SK CG  L P A R   R
Sbjct: 25  VQTWDVIIAGAGPAGSIAAITLADMGHRVLLTDRDW---FPRSKVCGDCLTPGAMRILRR 81

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVYH 119
            GL     + A  +   ++ +   A +  +    Y+ + R   D  + +  + A V    
Sbjct: 82  YGL-FDAALHAGHRCTQMR-IYSPAHVRIDVPGDYLTVKREILDQLLARKALAAGVTFVR 139

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQ 179
            +      R D +  V FR +G    +    L+   G  ++ ++     H +    A++ 
Sbjct: 140 GTAAALEKRGDAEIAVRFR-EGPSMQVARCGLLATGGRLALAQKSGLVAHPVASGAAVRC 198

Query: 180 WFAEKHPVPFYSCIFDNSITNCYSWSIS--KDGYFIFGGAYPMKDGQTRFTTLKEKMSAF 237
           +   + P+       + +I   Y+W     KD Y +  G +  +  +     LK    AF
Sbjct: 199 YVRSRLPIKHMVIACERTILPGYAWIFPVEKDLYNVGCGRFMYRQTEPHL-HLKRSFHAF 257

Query: 238 QFQF---------GKTVKSEKCTVLFPSRWQDFVCGKDNAFL-IGEAAGFISASSLEGIS 287
              F         G      K  VL  S WQ        A L +GE  G  S  + EGI 
Sbjct: 258 LHTFPIARELMEQGDMETPLKGAVLR-SGWQHIGPMASGACLGMGEMVGTTSPYTGEGIG 316

Query: 288 YALDSTDILR----SVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMR 343
            A+ S  +        L K        Y    R LR   +    ++R      L    + 
Sbjct: 317 KAMQSGVLAAKLVHRCLRKGDMSELLRYPGYLRLLRGMCYDGFERTRKWFEHPLLVDFLA 376

Query: 344 SGVAHIPQLKD 354
             + H P L D
Sbjct: 377 HRINHSPYLYD 387


>UniRef50_A5D4V1 Dehydrogenases n=1 Tax=Pelotomaculum thermopropionicum SI
           RepID=A5D4V1_PELTS
          Length = 386

 Score =  207 bits (527), Expect = 5e-52,   Method: Composition-based stats.
 Identities = 84/351 (23%), Positives = 127/351 (36%), Gaps = 34/351 (9%)

Query: 3   HFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            +DV I G GPAGS LAR+LAG  ++V+ L+K+         KPCGG +   A R     
Sbjct: 2   KYDVVIAGAGPAGSTLARRLAGAGLEVLVLEKEFM----PREKPCGGGITYKAARLLDFP 57

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRS-YININRHAFDLWMKSLI-PASVEVYH 119
                 DVI +    +V +    + +T   +      + R +FD  +      A   +  
Sbjct: 58  ----WQDVIEDTVHTAVFSYQGKSEVTVRLKTPLAYMVTRSSFDRMLADRARQAGACLVE 113

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQ 179
            +  + I  E+    V    +        R  VGADG N      L   H       ++ 
Sbjct: 114 GAPVKDIAVENGLVTVAAAGE----TYHGRLFVGADGVNGRSAMLLGLHHPGETGPTLEA 169

Query: 180 WFAEKHPV---PFYSCIFD-NSITNCYSWSISKDGYFIFG-GAYPMKDGQTRFTTLKEKM 234
             A    V      +   D  ++   Y W   K      G GA+  K        LK+ +
Sbjct: 170 EVACPPEVLEQKRGTIRLDCGAVPWGYGWVFPKRDRLSTGVGAFTRK-----VKELKKLL 224

Query: 235 SAFQFQFGKTVKSEKCTVL----FPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYAL 290
             F  + G    S +   L     PS  +       +A LIG+AAG +   S EGI YA+
Sbjct: 225 GGFLAREGLG--SARILSLRGYPIPSGGRKKRIHSRSALLIGDAAGLVDPFSGEGIYYAI 282

Query: 291 DSTDILRSVLL---KQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALR 338
            S  +    +L    QPE     Y     +       +  +   +     R
Sbjct: 283 KSAHLAAEAILDSRAQPEGAPGLYQSLVDRHVTAELMEARRLARVFYTFPR 333


>UniRef50_B0JID7 Geranylgeranyl reductase n=8 Tax=Cyanobacteria RepID=B0JID7_MICAN
          Length = 378

 Score =  206 bits (523), Expect = 1e-51,   Method: Composition-based stats.
 Identities = 80/320 (25%), Positives = 130/320 (40%), Gaps = 16/320 (5%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           FD  IIG GPAG+     LA K + I +  K +       KPCGG ++P  ++ F  D  
Sbjct: 2   FDCIIIGAGPAGATAGYHLAKKGRTILILDKAKL---PRYKPCGGGVSPAIKQWFDFDF- 57

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVYHDSL 122
           T  ++       F+ K  D AA+   N       + R  FD ++ +  I     +  +S 
Sbjct: 58  TPVIENTVTQVEFTWKQGD-AATTKLNMLEPMWMVQRDRFDDFLGQQAIAVGATIQDNSE 116

Query: 123 CRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFA 182
             +I    D W V           + +YL+ ADG      R L    + +   A  +   
Sbjct: 117 VTQIKFVQDHWQVTTSQ----GTFSGKYLIAADGVKGNTSRWLGLPAKNQAIGATLEITN 172

Query: 183 EKHPVPFYSCIFD-NSITNCYSWSISK-DGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ 240
            +  +P     FD  S+ N Y W+  K +GY I GG +    G  +   LK+++  +  Q
Sbjct: 173 AEATIPPQKAFFDFGSLKNGYIWAFPKSNGYTISGGCF---KGSIKSEELKKQLLNYARQ 229

Query: 241 FGKTVKSEKCTVLFPSRW-QDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSV 299
            G  ++  + +    + W  +      NA + GEAAG +     EGI  A+ +       
Sbjct: 230 KGWNLEDYRYSEYALALWNGNKPLHAQNALITGEAAGILDPLIGEGIRPAILTGVKAAEA 289

Query: 300 LLKQPEKLNTAYWRATRKLR 319
           + +     N A    +R +R
Sbjct: 290 IDRALAGDNQALAGYSRIIR 309


>UniRef50_B9M019 FAD dependent oxidoreductase n=1 Tax=Geobacter sp. FRC-32
           RepID=B9M019_GEOSF
          Length = 353

 Score =  206 bits (523), Expect = 1e-51,   Method: Composition-based stats.
 Identities = 79/356 (22%), Positives = 125/356 (35%), Gaps = 38/356 (10%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M+ +DV I G GPAGS  A+ L      V+ L+K+         K C G+L    Q    
Sbjct: 1   MQQYDVVIAGSGPAGSTCAKALKDEGFSVLVLEKEIL----PRHKTCSGVLFGQTQELIR 56

Query: 60  RDGLT-LPVDVIANPQIFSVKTVDVAASL-------------TRNYQRSYININRHAFDL 105
               T +P +V    +      +                    R + R+Y NI R  FD 
Sbjct: 57  AYFGTHVPAEVYCGNKFVEADDIREWDDEQGYIPYTWEIDKDGRKFSRTYHNIWRDKFDK 116

Query: 106 WMKSLIPASVEVYHDSLCRKIWREDDK--WHVIFRADGWEQHITARYLVGADGANSMVRR 163
           W+     +  E    +  +           HV              Y VGADG +S VRR
Sbjct: 117 WLLD--QSGAEYRDGAKVKAFDAGGSTVDVHVHMSRTNESAVFKCEYFVGADGNDSTVRR 174

Query: 164 HLYPDH----QIRKYVAIQQWFAEKHPVPF----YSCIFDNSITNCYSWSISKDGYFIFG 215
            L+  +    Q  K  + Q ++  K         ++      I +       KD Y +  
Sbjct: 175 LLHAQNPEYAQRHKLASYQSYYKVKSLGSLKPNGWTVFLRQEIGDYILCVHQKDEYLVMH 234

Query: 216 -GAYPMKDGQTRFTTLKEKMSA-FQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGE 273
            G    ++ +      KE +S  F   FG+  + E CT            G++   + GE
Sbjct: 235 VGGMDGRNLRQSMEKFKELLSGRFGVSFGEHWRDEGCTCELLP----IFLGQEKVLVTGE 290

Query: 274 AAGFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKS 329
           AAGFI   + EGIS A+DS       + +      ++      +    +   + + 
Sbjct: 291 AAGFIY-LNCEGISAAMDSGYRCGKAIAQALRSNGSSARDLYGEACRDILQHMDRC 345


>UniRef50_B5YGK5 Geranylgeranyl hydrogenase, putative n=1 Tax=Thermodesulfovibrio
           yellowstonii DSM 11347 RepID=B5YGK5_THEYD
          Length = 378

 Score =  205 bits (520), Expect = 3e-51,   Method: Composition-based stats.
 Identities = 75/344 (21%), Positives = 126/344 (36%), Gaps = 18/344 (5%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI--- 59
             +V ++G GPAGS  AR LA K     L +K       F+KPCGG +     + F    
Sbjct: 2   QCEVLVVGGGPAGSTAARLLAEKGIETVLIEKDLT----FNKPCGGGIPSAGLKEFNILN 57

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYH 119
           +    +P +++   +IF   +  +  SL        +  NR +FD +M+ L   S     
Sbjct: 58  KLQNQIPFNIVTKVKIFPPFSEPIEVSLQGGE---ILIFNRQSFDSFMRKLAEKSGVKII 114

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMV-RRHLYPDHQIRKYVAIQ 178
           ++    I   + K  V  +  G    I ++Y++ ADG NS V     +   +    V++ 
Sbjct: 115 EAELINIE--NSKLTVR-KKTGEVLEIYSKYIIAADGVNSRVCSIKGWSKPEYYWTVSLH 171

Query: 179 QWFAEKHPVPFYSCIFDNS-ITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAF 237
                          F NS  +  YSW      YF  G      +   +  TL +     
Sbjct: 172 VLENFIDTKDTCEFWFGNSHASFFYSWVFPGVDYFSVGTGA---EDIKKLKTLIDNFVEK 228

Query: 238 QFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILR 297
           +F     + S K       +W      K+N    G+  G +   S EGI Y++ S     
Sbjct: 229 RFAGKLNINSFKLRAYKIPKWGRRSFFKENVIFCGDTLGTVMPISFEGIYYSMKSAQFAS 288

Query: 298 SVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWI 341
             ++++   L    W      +  +  K           +  W+
Sbjct: 289 EAIVQKDLNLYKKLWDENFLKQFSIMKKFQDYMFGNDERIDNWL 332


>UniRef50_Q11W52 Probable electron transfer flavoprotein n=1 Tax=Cytophaga
           hutchinsonii ATCC 33406 RepID=Q11W52_CYTH3
          Length = 384

 Score =  202 bits (513), Expect = 2e-50,   Method: Composition-based stats.
 Identities = 75/347 (21%), Positives = 122/347 (35%), Gaps = 30/347 (8%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
            FDV I+G GPAGS  A  L      +AL +K         K CG  L+  A+R   +  
Sbjct: 8   SFDVIILGAGPAGSTAALALQKSNLTVALLEKEL---FPRDKICGDALSCVAERVLKQID 64

Query: 63  LTLPVDVIANPQIFSVK----TVDVAASLTRNYQRSYININRHAFDLWMKSLIPAS-VEV 117
            +L  +++   +   V           S+  N+ +    I R  FD W+     A  +EV
Sbjct: 65  PSLEQELLLYSEKTVVNKARVYSPEFRSIVLNFSKRGHCIKRLDFDNWLFEKANAKNIEV 124

Query: 118 YHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYV-- 175
           +  +    +  ++    V+   DG   H  A  ++  DGA+S+  R L      RK+   
Sbjct: 125 FQQAKVTDVRIDNSGAEVVL-QDGTILH--AAIVICCDGAHSVAARQLTHLKLDRKHYVG 181

Query: 176 AIQQWFAEKHPVPF--YSCIFDNSITNCYSWSIS-KDGYFIFGGAYPMKDGQTRFTTLKE 232
           A++Q++              F       Y W    K+G    G              LK+
Sbjct: 182 AVRQYYRNISDTAGNELEIFFLKDFLPGYFWIFPLKNGEANVGFGALSAIISKNKIDLKK 241

Query: 233 KMS-------AFQFQFGKTVKSEKCTVL-FPSRWQDFVCGKDNAFLIGEAAGFISASSLE 284
            +          + +F      E       P   +       +  L G+AA  I   + E
Sbjct: 242 SLQEIIQSVPQLKERFKDAEAMETVKGFGLPLGSRKLPISGAHFMLCGDAASLIDPVTGE 301

Query: 285 GISYALDSTDILRSVLLKQPEKLN------TAYWRATRKLRLKLFGK 325
           GI  A++S        ++  E  +       AY +   K   K F +
Sbjct: 302 GIETAMESGKYAAEQAIRCFESTDFSAACMQAYDQRIHKKMFKRFRQ 348


>UniRef50_Q2RKB3 Geranylgeranyl reductase n=1 Tax=Moorella thermoacetica ATCC 39073
           RepID=Q2RKB3_MOOTA
          Length = 378

 Score =  197 bits (500), Expect = 7e-49,   Method: Composition-based stats.
 Identities = 70/327 (21%), Positives = 101/327 (30%), Gaps = 19/327 (5%)

Query: 3   HFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            +DV I G GPAGS   R LA   ++V   D+          KPCGG L   AQ      
Sbjct: 2   QYDVLICGAGPAGSTCGRLLARQGLKVAIFDR----ARFPRYKPCGGGLTGKAQGELEAG 57

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMK-SLIPASVEVYHD 120
              L  D       +  +   +  +     Q     ++R  FD W+      A  EV   
Sbjct: 58  WEDLIEDTTREVIFYHRQERPLKITC---EQPVIKMVSREKFDSWLLTEAARAGAEVRDG 114

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW 180
                +        V             R+LVGADGA S+VRR L         + ++  
Sbjct: 115 YRVTGVTETAGGVKV---QGQDGCTWEGRFLVGADGALSLVRRSLPFKPGGTAGITLECE 171

Query: 181 FAE----KHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSA 236
                           +    I   Y W   K  +   G     +  +            
Sbjct: 172 VPVDAGLLTSYRGQVHLSYGGIPYGYGWVFPKGDHLSVGIGSFTRRVKGLRRYFDTFCRG 231

Query: 237 FQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDIL 296
                   ++     +         V     A L+G+AAG +   S EGI YAL S  + 
Sbjct: 232 LGLAVPANLRCRGAVIPAADGQAG-VFHTGRALLVGDAAGLVDPFSGEGIYYALRSGRLA 290

Query: 297 RSVLLK--QPEKLNTAYWRATRKLRLK 321
              ++          AY R      L+
Sbjct: 291 AETIMATLAGTGEPGAYSRRLYDELLQ 317


>UniRef50_Q2NER9 Digeranylgeranylglycerophospholipid reductase 3 n=2
           Tax=Methanosphaera stadtmanae DSM 3091 RepID=GGR3_METST
          Length = 397

 Score =  192 bits (487), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 82/349 (23%), Positives = 137/349 (39%), Gaps = 28/349 (8%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCG-GLLAPDAQRSF 58
           ++  DV IIG GPAGS  AR+ +    + + +DKK + GT    K C  G+++   +R  
Sbjct: 3   IKEVDVLIIGAGPAGSLAAREASKNGAKTLIIDKKSEIGT---PKRCAEGIMSGVLERVH 59

Query: 59  IRDGLTLPVDVIANPQIFSVKTVDVA-ASLTRNYQRSYININRHAFDLWMK-SLIPASVE 116
           I          I   +I S           T     + I + R  FD  M    I    E
Sbjct: 60  ITPDERWIARKIDGARIVSPNNTSAWFTPETLETPATGIILERKVFDKHMTMDAIREGAE 119

Query: 117 VYHDSLCRKIWREDDKWHVIFRADGWEQ-HITARYLVGADGANSMVRRHLYPDHQIRKYV 175
           V   +    + RE D + V  ++   E   I A  ++GADG    V R      ++   V
Sbjct: 120 VMIKTEALSMKREGDGYLVDIKSFNKEYNQIKAHIVIGADGPEGHVARW----AELNTKV 175

Query: 176 AIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGY-FIFGGAYPMKDGQTRFTTLKEKM 234
            + +  +          + +NS+   +  S++  GY +IF   Y   +     + +K + 
Sbjct: 176 PLAEMESGLQYEMTNLKMKNNSVIQFFFGSVAPGGYAWIFPKGYDTANVGIDISGIKAEK 235

Query: 235 SAFQFQ---FGKTVKSEKCTVLFPSRWQDFVCG------KDNAFLIGEAAGFISASSLEG 285
           SA ++         +++   ++  +   + +CG       DN  L+G+AAG +S  +  G
Sbjct: 236 SAVKYLNDFIANCDETKDGQIVEINAGGNPLCGIFDKIITDNVMLVGDAAGCVSPITGGG 295

Query: 286 ISYALDSTDILRSVLLKQ------PEKLNTAYWRATRKLRLKLFGKIVK 328
           I  AL+S  I   V  K        E+    Y         K F K + 
Sbjct: 296 IDTALESGMIAGRVAAKAIKNRDYSEEKLQEYADYIDSHLGKKFKKYIA 344


>UniRef50_Q4JN54 Putative uncharacterized protein n=1 Tax=uncultured bacterium
           BAC13K9BAC RepID=Q4JN54_9BACT
          Length = 369

 Score =  191 bits (486), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 64/338 (18%), Positives = 113/338 (33%), Gaps = 17/338 (5%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQ-VIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           ++  D+ I+G GP+G   A  L    + V  LDK          KPC G L P       
Sbjct: 5   IKETDILIVGAGPSGCMAASILKDSGRNVTLLDK----NDFPRHKPCAGGLTPKTVDEL- 59

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYH 119
                +      + +    K  +       N   +   + R  FD +  + +        
Sbjct: 60  --PFEIADLKQHDSEKMLFKFTNGKTVDLNNESGACKMVVREEFDNFFLNYVKNKGTELM 117

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQ 179
                 I+   ++  V    +  +  I  ++L+GADGANS VRR            A + 
Sbjct: 118 KGKVTAIYDAPNEVVV----ETSDYKIKCKFLIGADGANSTVRRLTTDLEFKNPVFAFEG 173

Query: 180 WFAEKHPVPFYSCIF-DNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQ 238
               K         F  N +   Y W   K  ++  G    + D         +  S  +
Sbjct: 174 LVDRKISAKDVPTKFVFNEL--GYGWIFPKKEHYNVGIGNLVFDPTQPKPKKNDLFSFVK 231

Query: 239 FQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRS 298
            + G    +        +   ++    +  +LIG+AAG       EGI  A+ S   + +
Sbjct: 232 DELGTNEVTHITGFPIGTEGNEYFPTSERIYLIGDAAGLAETLLGEGIYNAVISGKYIAN 291

Query: 299 VL--LKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTA 334
            +     P+ +   Y +    ++ +L      S+ L  
Sbjct: 292 SIVGTNNPKDVYKKYLKFLVGMKKELALYNKASKILYK 329


>UniRef50_B8GFT3 Geranylgeranyl reductase n=1 Tax=Methanosphaerula palustris E1-9c
           RepID=B8GFT3_METPE
          Length = 401

 Score =  188 bits (476), Expect = 4e-46,   Method: Composition-based stats.
 Identities = 76/362 (20%), Positives = 128/362 (35%), Gaps = 40/362 (11%)

Query: 5   DVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           DV ++G GPAG   A  LA    QV+ +DK     T    K C G L    +    R   
Sbjct: 13  DVVVVGAGPAGVTAAYLLAKDGHQVLLIDK----ATFPRKKLCAGCLTEKTRDLLSRTFG 68

Query: 64  TLP--------VDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPA-S 114
                      V   A+    S +   +     RN    +  ++R A+D  + +      
Sbjct: 69  LTETYMIREGIVAATADHYQISCRREMIC---KRNTSIPFTFVDRTAYDAKLLAAAEEAG 125

Query: 115 VEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRH--LYPDHQIR 172
           V V        +   D    ++   DG  + IT RYL+GADG NS VR    + P+ + R
Sbjct: 126 VTVITGCEVTSV---DPLIGLVMTRDG--RTITGRYLIGADGVNSRVRHAFPITPEDKNR 180

Query: 173 KYVAIQQWFAEKHPVPFYSCIFDNSITN-----------CYSWSISKDGYFIFGGAYPMK 221
            +  +      K P    +  F                  Y W+   +   I G     +
Sbjct: 181 WFQNLASTVEIKVPRSRLAPPFSGIDHPILFFDLPGWKAGYGWAFPGEEEVILGIGGLKQ 240

Query: 222 DGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISAS 281
            G+ R   + +   A +         +   + + +  ++   G   A L+G+A GF+   
Sbjct: 241 GGERRVAEIFKTCLAAKGLEDMVSHPQGWALPYGNFIRNPTFG--VALLVGDAGGFVEPF 298

Query: 282 SLEGISYALDSTDILRSVL---LKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALR 338
             EGI YA  + ++  + +   L +       Y +  R L        ++ R L    + 
Sbjct: 299 LGEGIFYAHRTGELAAAAVHRALSEGGDAADHYQQLIRSLICPELKADLRGRNLLFHLVH 358

Query: 339 KW 340
           + 
Sbjct: 359 RL 360


>UniRef50_UPI0001C42077 geranylgeranyl reductase family protein n=1 Tax=Methanobrevibacter
           ruminantium M1 RepID=UPI0001C42077
          Length = 432

 Score =  186 bits (472), Expect = 1e-45,   Method: Composition-based stats.
 Identities = 66/310 (21%), Positives = 124/310 (40%), Gaps = 18/310 (5%)

Query: 3   HFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            +DVAI+G GP GS+LA +LA   ++V  +DKK + G       C G++        I  
Sbjct: 4   DYDVAIVGAGPIGSSLAYELAQNGLKVCLIDKKKRIG---LPLQCAGIVNKR-----ISS 55

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDS 121
              +P ++I N    +       +      +     ++R AFD ++ +     ++ Y  S
Sbjct: 56  LCDIPKELILNEAKGAFIHSKNHSLTVSKKESQAYVLDRVAFDQYLFNRAREHLDTYLSS 115

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWF 181
               I  E     V F+ D   + I ++ +VGADG  S+  + +        Y    Q+ 
Sbjct: 116 KVVDIDTELG--IVQFKFDCEIKTIRSKIIVGADGPLSLSAKKVNSKL---NYFNASQYL 170

Query: 182 AEKHPVPFYSCI---FDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQ 238
            +   +   S +       +   + W+I         G +   D +++   L + +   +
Sbjct: 171 VKVDKIDEMSFVDLYAWGDLFPGFIWAIPVYSNIYRIGLFSEDDYKSQSKMLDDYLEN-E 229

Query: 239 FQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRS 298
           F++ +    EK     P   +     K+   LIG+AA  +  ++  GI   L+S    + 
Sbjct: 230 FRYDEYEVLEKYKGKIPIYDKSNKLFKNRLILIGDAASQVKPTTGGGILIGLESVQFAKD 289

Query: 299 VLLKQPEKLN 308
            +L     L+
Sbjct: 290 AILNALNTLD 299


>UniRef50_O29786 Digeranylgeranylglycerophospholipid reductase n=1 Tax=Archaeoglobus
           fulgidus RepID=GGR_ARCFU
          Length = 387

 Score =  185 bits (469), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 71/346 (20%), Positives = 119/346 (34%), Gaps = 21/346 (6%)

Query: 4   FDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDA-QRSFIRD 61
           +DV ++G GPAGS  A+  A   ++V+ ++K+ + GT      C   ++ ++ ++ F  D
Sbjct: 2   YDVVVVGAGPAGSMAAKTAAEQGLKVLLVEKRQEIGTPVR---CAEGISRESIEKFFEVD 58

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKS-LIPASVEVYHD 120
              +  +V         KT  V +      +  Y+ + R  FD  +      A  EVY  
Sbjct: 59  KKWIAAEVTGAKIYAPNKTEIVMSEEMAGNEVGYV-LERKIFDRHVARLAAKAGAEVYVK 117

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRH---LYPDHQIRKYVAI 177
           +      R+D K  V  R  G +  +  + L+GADG  S + R    +            
Sbjct: 118 TAMVDFERKDGKVKVKLRRLGEDWEVETKILIGADGVESKIGRKAGIIKTLKLNEVESCA 177

Query: 178 QQWFAEKHPVPFYSCIFDNS--ITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMS 235
           Q           Y+  +         Y+W   K       G   +     R  T KE + 
Sbjct: 178 QYLMTGLDIDESYTYFYLGRELAPGGYAWIFPKGNGSANVGIGVLPKMAER--TAKEYLD 235

Query: 236 AFQFQFG-KTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTD 294
           AF  + G +    E      P   +      DN  L G+AA      +  GI+ AL +  
Sbjct: 236 AFIEKEGIEGKIVEFVAGAVPVYGEIETAVADNIMLAGDAAYHADPITGGGIANALSAGY 295

Query: 295 ILRSVLLKQ------PEKLNTAYWRATRKLRLKLFGKIVKSRCLTA 334
               V  +              Y    +    K   +  K +    
Sbjct: 296 YAGKVAAEAVQKNDFSADFLRRYDELWKNDFGKKLRRNKKLQLKFI 341


>UniRef50_A8M2V9 Geranylgeranyl reductase n=5 Tax=Actinomycetales RepID=A8M2V9_SALAI
          Length = 406

 Score =  184 bits (468), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 75/321 (23%), Positives = 117/321 (36%), Gaps = 18/321 (5%)

Query: 29  IALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTVDVAASLT 88
           + LD+          K CG  +A  A       G+  PV   A P            ++ 
Sbjct: 57  LLLDRVG----FPRDKACGDGIAAHALDVLDELGVPDPVAGYA-PVSTLRLVAPSGGAVA 111

Query: 89  RNYQRSYININRHAFDLWMKSLIPASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITA 148
           R   R    + R  FD  + +   A+         R++    D+  +       +  ITA
Sbjct: 112 RALPRQAYTVPRTVFDARLVAAAVAAGARLRRHAVRQVEVRADRVVL-------DGRITA 164

Query: 149 RYLVGADGANSMVRRHLY--PDHQIRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSI 206
           R +VGADGA S+VRR L   P+      +AI+ +       P    +   +    Y+WS 
Sbjct: 165 RAVVGADGAGSVVRRALGHRPNPDRHLALAIRGYAPAPSGRPEQLIVTSATRWPAYAWSF 224

Query: 207 S-KDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGK 265
              DG    G    ++        L E++ A          +       P      V G+
Sbjct: 225 PIGDGRANVGYGEVLRGESLTRGHLLERLGALLPGVDPAAVTALRAHHLPLSTHRPVPGR 284

Query: 266 DNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGK 325
             A L G+A   I+  + EGI YAL S  +  +   + PE     Y  A   LR +L G 
Sbjct: 285 GRAVLAGDALSLINPFTGEGIFYALLSGTLAGAAASRAPEHAARRYAEA---LRRRLGGH 341

Query: 326 IVKSRCLTAPALRKWIMRSGV 346
           +  S      A R+ ++ + V
Sbjct: 342 LRHSSAAAWLARRRSVVDAAV 362


>UniRef50_A1U6D3 Geranylgeranyl reductase n=2 Tax=Marinobacter RepID=A1U6D3_MARAV
          Length = 374

 Score =  183 bits (464), Expect = 9e-45,   Method: Composition-based stats.
 Identities = 69/316 (21%), Positives = 103/316 (32%), Gaps = 23/316 (7%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           ME++D+ I+G GPAGS LAR L    + + +  K         K C G + P    S   
Sbjct: 1   MEYYDIIIVGAGPAGSTLARALEDSGKRVLIIDKQ---AFPRDKTCAGWVTPAVMASLDI 57

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQR-SYININRHAFDLWMKSLIPASVEVYH 119
           D     V     P       +   +++  ++       I R  FD ++        E   
Sbjct: 58  DPGKYSVGRTLQPIRRFRIGMMGQSAVENDHGDIVSYGIRRCEFDDYLLDRAE--CEKQL 115

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYP-DHQIRKYVAIQ 178
            +  + I R +  W +            A  LVGA G    V R L     +    VA +
Sbjct: 116 ATAVKSINRNNGNWVI-------NDQWQAPLLVGAGGHFCPVARLLGDGPGKHETVVAAK 168

Query: 179 QWFAEKHPVPFYSCIFDNSITN--------CYSWSISKDGYFIFG-GAYPMKDGQTRFTT 229
           +   E  P    +C                 Y+W   K  Y   G G             
Sbjct: 169 EVEFEMTPEQARACEARGDTPELWFCRDLKGYAWVFRKGSYLNIGLGREDNHRLSDHLEA 228

Query: 230 LKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYA 289
             E+M              K          +     D   LIG+AAG     S EGI  A
Sbjct: 229 FVEEMKQSGRIPSDLPGRFKGHAYLLYAHANRPLVDDGVLLIGDAAGLAYTQSGEGIRPA 288

Query: 290 LDSTDILRSVLLKQPE 305
           ++S  +  +V+   P+
Sbjct: 289 IESALMAANVIKAAPD 304


>UniRef50_Q2S264 FAD dependent oxidoreductase, putative n=1 Tax=Salinibacter ruber
           DSM 13855 RepID=Q2S264_SALRD
          Length = 385

 Score =  183 bits (463), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 87/379 (22%), Positives = 143/379 (37%), Gaps = 48/379 (12%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           +D  +IG G +G + A +LA +   + L ++    T    K CG  L+P+AQ SF R G+
Sbjct: 3   YDALVIGGGLSGCSTALQLAREGHDVLLAEQS---TYPRQKLCGEFLSPEAQSSFRRLGV 59

Query: 64  TLPVDVI-ANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVYHDS 121
              V    A P   +  T    A+ + +   + +  +R+  D  + +      VE    +
Sbjct: 60  LDDVRAAGAEPIGRTCLTTSSGATTSHSLPDAALGFSRYRLDQLLFQKACTMGVEGRSGT 119

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPD--HQIRKYVAIQQ 179
               I          F A      + AR ++GA G  S + R L      +   YVA + 
Sbjct: 120 RVTNIR---GGLRDGFVASVGGDSVEARLVLGAHGRRSRLDRSLERPFLSENTPYVAFKA 176

Query: 180 WFAEKHPVPFYSCIFDNSITNCYS-------------WSISKDGYFIFGGAYPMKDGQTR 226
            +A        + I  +S    Y              W    D     GG+    +G   
Sbjct: 177 HYAGPTAAALENTIELHSAPGAYCGLSPVEGNRINVCWIGRTDALKDAGGS---PEGMLN 233

Query: 227 FTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGI 286
            TTL++  +  +   G T  S++   +            D+  +IG+AAG I+    +G+
Sbjct: 234 -TTLRQNPAFDERLSGLTRVSDRFEAVSQVPLMPKSRFADDVCMIGDAAGMIAPLCGDGM 292

Query: 287 SYALDSTDI---LRSVLLKQ---PEKLNTAY---WRATRKLRLKLFGKI----------- 326
           + AL + D+   L S  L          T+Y   W  T   R++L   I           
Sbjct: 293 AMALRTADLVSPLASDFLNGRHPAHAFRTSYETAWTDTFGQRMRLGRWIHAAAFRPGAAW 352

Query: 327 -VKSRCLTAPALRKWIMRS 344
            +   C   P L +WI+RS
Sbjct: 353 TLVQSCRLLPPLAQWIIRS 371


>UniRef50_Q6ALA8 Related to dehydrogenases (Flavoproteins) n=1 Tax=Desulfotalea
           psychrophila RepID=Q6ALA8_DESPS
          Length = 352

 Score =  181 bits (459), Expect = 3e-44,   Method: Composition-based stats.
 Identities = 80/343 (23%), Positives = 130/343 (37%), Gaps = 52/343 (15%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           ME FD+ IIG GPAG A A++       V+ L++  Q G     K C G +         
Sbjct: 1   MEFFDIVIIGAGPAGLACAKEAGKRGYSVLVLERNGQIGR----KVCAGGIT-------- 48

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYI--------NINRHAFDLWMKSLI 111
            +GL   +   A  + F+         L   YQ   I         +NR      M    
Sbjct: 49  WNGLMRHMPGFATERDFA------KQHLFSRYQSCCIEADHPIVATLNREHLGRSMAEQA 102

Query: 112 PASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPD--- 168
             +  V   +  + +    +K  V  R  G +  +  +YLVGADG++S+VRR+L      
Sbjct: 103 QEAGAVIR-TEEQALQIGAEKITVRERKTGRDYSVAFKYLVGADGSSSLVRRYLGQPVKH 161

Query: 169 ------HQIRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKD 222
                  QIR      +W                   N Y+W          G AY  + 
Sbjct: 162 IGLGLNFQIRGRAEKMEWHLRPD-----------LFVNGYAWIFPHQNTISIG-AYADRS 209

Query: 223 GQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFP-SRWQDFVCGKDN-AFLIGEAAGFISA 280
             +  T LK +   +    G  ++ E+CT  +    ++ +  G DN  FL G+AAG  S 
Sbjct: 210 IFSP-TELKRRFLVWAKAQGYGLEQERCTAGYINYDYRGYRFGSDNNIFLTGDAAGLASG 268

Query: 281 SSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLF 323
            + EGI  A+ S   +   +    +         +++++ ++ 
Sbjct: 269 LTGEGIYPAIVSGIAVAEEIAGCKDHPELEAVIKSQRMQRRIL 311


>UniRef50_B3QZ41 Geranylgeranyl reductase n=12 Tax=Chlorobiaceae RepID=B3QZ41_CHLT3
          Length = 383

 Score =  181 bits (458), Expect = 5e-44,   Method: Composition-based stats.
 Identities = 60/302 (19%), Positives = 115/302 (38%), Gaps = 18/302 (5%)

Query: 38  GTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYIN 97
                +KPCGG +       F      +P +++                +  +    ++ 
Sbjct: 33  RNFNNTKPCGGAIPLGLIEEFA-----IPDEIVERKVDHMAVRSPKGRVIEMHMPTGFVG 87

Query: 98  -INRHAFDLWMKSLIPASVEVYHDSLCRKIWREDDKWHV-IFRADGWEQHITARYLVGAD 155
            + R  FD +++    A      ++  RK+ + +  + + +  A      I A+Y++GAD
Sbjct: 88  MVRRERFDRFLRERAAADGTELLEAKMRKVRKTNGVYQISVDAASKGVSEIEAKYVIGAD 147

Query: 156 GANSMVRRHLYPDHQIRKYVAIQQWFAEKHPVPFYSCI----FDNSI-TNCYSWSISKDG 210
           GANS V   L       K +AIQ+ F     +  Y+ +    FD  +  + Y W   K  
Sbjct: 148 GANSKVANELGFPPNEYKAIAIQERFHYSPALERYNNLVEIWFDGEVSPDFYGWIFPKAD 207

Query: 211 YFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFL 270
           +   G     K G      +++  + F+ + G  ++                  +++A L
Sbjct: 208 HVAIGTGTDDKHG-----NIRKLQARFREKIGLDIEPYLEEAAKLPMHPRKSFTQESAML 262

Query: 271 IGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSR 330
           +G+AAG ++ S+ EGI +A+ S  +    L         +   A      KL+  I K  
Sbjct: 263 VGDAAGLVTPSNGEGIFFAMRSGKMAGQTLANFINGQEKSL-HAYEANFHKLYKIIFKGL 321

Query: 331 CL 332
            +
Sbjct: 322 GM 323


>UniRef50_C8X2V2 Geranylgeranyl reductase n=1 Tax=Desulfohalobium retbaense DSM 5692
           RepID=C8X2V2_DESRD
          Length = 384

 Score =  180 bits (456), Expect = 8e-44,   Method: Composition-based stats.
 Identities = 75/365 (20%), Positives = 125/365 (34%), Gaps = 31/365 (8%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDA----Q 55
           M  FD  ++G GP+G A A+ +A    +V+ LDK          K C G++        +
Sbjct: 1   MHRFDAIVVGGGPSGCAAAKGIADAGGEVLLLDK----AAFPRPKLCAGVITAKTVAVVE 56

Query: 56  RSFIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNY-QRSYININRHAFDLWMKS-LIPA 113
           R F  D  +L             + V     L  +     +  + R +FD  +      A
Sbjct: 57  RVFGLDTASLHACGALKAATPRYRVVTRQRVLLEDSAPDPFRLVERRSFDHLLLQRAAAA 116

Query: 114 SVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRK 173
                 ++    I     +           +   AR ++GADG +S VRRHL P  Q R+
Sbjct: 117 GARCVTETPVTGIDPRRGEVK-----TAAGETFQARVVIGADGVHSRVRRHLTPRVQARR 171

Query: 174 Y--------VAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQT 225
           Y        V I     +         +    + + Y+W+  +    I G       G+ 
Sbjct: 172 YWRQRLAHCVEIVAPLQDLTHSHTSLGLHLGYVRHGYAWNFPRGEDIILGMCALPCRGER 231

Query: 226 RFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEG 285
                +E +    +      K        P         +D   L G+AAG       EG
Sbjct: 232 LDHAFQEFLGDIGYVGAAPFKGHP----LPYGNFLDTPVQDRVLLTGDAAGLADPLLGEG 287

Query: 286 ISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLF--GKIVKSRCLTAPALRKWIMR 343
           + +AL S ++     L  PE    AY +A        F   + ++   L    +    + 
Sbjct: 288 LYFALRSGELAAQAAL-SPEHGFFAYDKALHSEIYSDFCWAQRLRRTALFLLPVASGRLV 346

Query: 344 SGVAH 348
           +G+A 
Sbjct: 347 AGLAQ 351


>UniRef50_C6PBK9 Geranylgeranyl reductase n=1 Tax=Thermoanaerobacterium
           thermosaccharolyticum DSM 571 RepID=C6PBK9_CLOTS
          Length = 387

 Score =  178 bits (452), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 70/325 (21%), Positives = 118/325 (36%), Gaps = 19/325 (5%)

Query: 4   FDVAIIGLGPAGSALARKL-AGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +DV IIG GPAGS LAR+L A   + + ++K     T    K CGG + P   R +    
Sbjct: 2   YDVIIIGGGPAGSTLARRLSAQGYKALLIEK----FTMPRYKACGGGITP---RCYKMLD 54

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMK-SLIPASVEVYHDS 121
           L +   V       + K  +  + +    +     ++R  FD ++    + +  +V+   
Sbjct: 55  LDISDYVEDTTYKIAFKFPNNKSVVLETEKPIIYQVDRTKFDKYLIDKAVESGCDVHDGE 114

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWF 181
                +R  D   V+ + D        R LVGADG NS V       +  +      + +
Sbjct: 115 KFLDFYR--DGKEVVVKTDRG--QYKTRILVGADGINSTVAYKANLLNGEKGIALEAEVY 170

Query: 182 AEKHPVPFY---SCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQ 238
            +K  +        +  N+I   Y W   K      G    +         L   +    
Sbjct: 171 VDKCDIEKVRGEVVVDFNAIKYGYGWVFPKKDRLSIGVGTFLSKTSKIKENLSNMIDENV 230

Query: 239 FQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRS 298
               +  K     + FP+  +D     D   LIG+A       + EGI  A+ + +I   
Sbjct: 231 VGNVEECKIYGHQLSFPNG-KDGTYNNDKVILIGDATRLADPFTGEGIYNAILTANISFD 289

Query: 299 VLLKQPEK--LNTAYWRATRKLRLK 321
           V+ K        + Y    R+  + 
Sbjct: 290 VIEKYFNGKCELSEYTERLRREVVS 314


>UniRef50_A3V9M1 Geranylgeranyl reductase n=1 Tax=Rhodobacterales bacterium HTCC2654
           RepID=A3V9M1_9RHOB
          Length = 394

 Score =  178 bits (451), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 81/355 (22%), Positives = 140/355 (39%), Gaps = 39/355 (10%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
           + FDV +IG GPAGS+ A++       +AL  +         K CG L++P   ++  R 
Sbjct: 4   QDFDVVVIGAGPAGSSAAKRARDLGLSVALIDRA---VFPRPKLCGALISPRGNKAVKRV 60

Query: 62  G---LTLPVDVIANPQIFSV-----KTVDVAASLTRNYQRSYININRHAFDLWMKSLIPA 113
               ++  + +++    F          D    LT  Y        R  FD W++    A
Sbjct: 61  FDMEMSPEMYLVSRQVAFKWDGEELNRFDAPYDLTYTY--------RLDFDHWLQQAAVA 112

Query: 114 SVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHL----YPDH 169
                 D    ++    D  +++  +DG  + I  + L+GADGA S V +H+    Y   
Sbjct: 113 --AGAVDMQGTRVETIHDADNLLELSDG--RRIGYKVLIGADGAASPVAKHILGAAYDPD 168

Query: 170 QIRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTT 229
           +I  +    +      P    S  FD  +   Y W+  K G    G    +   ++    
Sbjct: 169 KI-GFAFETEAPGGCDPEALMSIDFD-IVHWGYGWNFPKAGSRTIG----LGAIRSVDQD 222

Query: 230 LKEKMSAFQFQFGKTVKSEKCT-VLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISY 288
           LK +M+ +    G    S        P        GK N  L G+AAGF+   + EGI+ 
Sbjct: 223 LKARMARYLAHEGVDPDSVTIKGAHIPLGDFKEKPGKGNVLLAGDAAGFVDGITGEGIAL 282

Query: 289 ALDST----DILRSVL-LKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALR 338
           A++S     +    V+   +P++ + AY+   + ++  L           + A+R
Sbjct: 283 AIESGAEAAEAAAQVIDEGRPQRADRAYFPRIKYIQTDLEKVRRLRVIAYSSAMR 337


>UniRef50_UPI0000D53425 oxidoreductase n=1 Tax=Psychroflexus torquis ATCC 700755
           RepID=UPI0000D53425
          Length = 310

 Score =  178 bits (451), Expect = 3e-43,   Method: Composition-based stats.
 Identities = 70/308 (22%), Positives = 123/308 (39%), Gaps = 22/308 (7%)

Query: 3   HFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLL-APDAQRSFIR 60
            +DV +IG GPAGS +AR  A G ++V+ +D +   GT      CG L+   D  R    
Sbjct: 6   DYDVIVIGGGPAGSTVARYAAEGGIRVLVMDARKSIGT---PLQCGELVPTNDEMRRLCP 62

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRN-----YQRSYININRHAFDLWMKSLIPASV 115
           D   +  D+   P     +  D    +T +     Y+   + +NR   D  + SL   + 
Sbjct: 63  DVPDMD-DLFQTPDEAISRKCDTMNIITPSGKSLSYRFEGLILNRVTHDEALVSLAKEAG 121

Query: 116 EVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYV 175
             Y   L     +E ++  V  R     +  TA+ +VGA G    VRR  + +  +   +
Sbjct: 122 AEY---LVNSFVKEVNENTVTTR---DGETYTAKVIVGAGGHKDPVRRKYWREKTVN--I 173

Query: 176 AIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMS 235
            ++    +          F +     Y+W   K      G    ++    +  +LKE  +
Sbjct: 174 PVKFELKDGDYGEAVELHFGSMAPGGYAWMFPKSVGANIGLG--IQKNFAKGKSLKEYST 231

Query: 236 AFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDI 295
           AF  ++ +   + K     P         K+N  L+G++AG +  S+  GI+ A+    I
Sbjct: 232 AFIDKY-EGESTFKGGGSLPMSGTIKRFVKENYVLVGDSAGMVLPSNGAGITIAMVGGRI 290

Query: 296 LRSVLLKQ 303
               + + 
Sbjct: 291 AGQAIARH 298


>UniRef50_C9R7U9 Geranylgeranyl reductase n=1 Tax=Ammonifex degensii KC4
           RepID=C9R7U9_AMMDK
          Length = 375

 Score =  178 bits (450), Expect = 4e-43,   Method: Composition-based stats.
 Identities = 64/347 (18%), Positives = 120/347 (34%), Gaps = 25/347 (7%)

Query: 3   HFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            + V ++G GPAG+  A  LA   + V+ L+K H        KPCGG L P A       
Sbjct: 4   SWPVIVVGAGPAGALCACSLARAGLSVLLLEKTH----FPREKPCGGGLTPKAAALLPFS 59

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRS-YININRHAFDLWM-KSLIPASVEVYH 119
             +    V+      ++  +    +L  N+ R     + R   D  + +    A   +  
Sbjct: 60  FQS----VVEGEVKRAILCLPGVEALEINWDRPVCFLVRREILDTHLAEQARQAGAFLRE 115

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQ 179
                +I    +   V            A+ ++GADGA S V R +   +     +A   
Sbjct: 116 GEEVVRIEETGEAVTVT---TAGGASYRAQLVIGADGALSRVARLVGRPYPRHFALAAAL 172

Query: 180 WFAEKHPVPFYSCIFDNS-ITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQ 238
                      + + D   +   Y W   K  +   G        + RF         F 
Sbjct: 173 IPPPAWAEKRDTILIDLEALPYGYGWVFPKIDHLNAGVGSFAATRELRF-----YWENFL 227

Query: 239 FQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRS 298
            + G                ++   G+    L+G+AAG +   + EG+  A  S ++   
Sbjct: 228 RRNGLARPFRLRAHPLALAGKETELGRGRVMLLGDAAGLVDPLTGEGLYAAFRSAELAAR 287

Query: 299 VLLKQ--PEKLNTAYWRATRKLRLKLFG---KIVKSRCLTAPALRKW 340
            +L++   E+  + Y    +   L+ +    ++ +      P + ++
Sbjct: 288 AILEKGVGERAVSRYRELVKASLLREYHFAYRLARLFYRFLPLIARY 334


>UniRef50_A0B5F9 Geranylgeranyl reductase n=1 Tax=Methanosaeta thermophila PT
           RepID=A0B5F9_METTP
          Length = 368

 Score =  173 bits (439), Expect = 7e-42,   Method: Composition-based stats.
 Identities = 63/351 (17%), Positives = 108/351 (30%), Gaps = 50/351 (14%)

Query: 4   FDVAII------------GLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLA 51
           +D+ +I            G G             + V+ ++K+         KPCGG L+
Sbjct: 2   YDLIVIGGGPAGASAALEGAGL-----------GLSVLLIEKEK----FPRYKPCGGALS 46

Query: 52  PDAQRSFIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSL 110
             A+         +P +VI               +     +R    + R  FD  + +  
Sbjct: 47  EKARSYLR---FRIPDEVIDAEVSRIRIFFRDRCAEISRPERLSTLVTRSVFDDILVRRA 103

Query: 111 IPASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQ 170
             A  EV        I  ED    ++       +    R LV ADG   M+ R + P   
Sbjct: 104 ADAGAEVLFGKKATGISEEDGCVRIM-----AGESYKGRLLVLADGHTGMLSRKICPGDG 158

Query: 171 IRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFG-GAYPMKDGQTRFTT 229
           +R    + +  AE+        I    +   Y+W      Y   G G     + +     
Sbjct: 159 MRGVCLVSEVAAEETN--DCMEIHFGEVDRGYAWVFPHGSYLSVGAGGLGSSNIRVIMDR 216

Query: 230 LKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYA 289
           L           G            P        G     L G++AG +   + EGI+YA
Sbjct: 217 LMRARGFRGRIHG---------HTIPLSGPSRYLGGRRTMLCGDSAGMVDPFTGEGIAYA 267

Query: 290 LDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKW 340
           + S  I   V  +             +    +  G  +++  L A  + ++
Sbjct: 268 VRSGQIAAQVASEHLSDGCD--LVEYQHRCKREIGDDLRASFLLARIMHRF 316


>UniRef50_C6BUN1 Geranylgeranyl reductase n=1 Tax=Desulfovibrio salexigens DSM 2638
           RepID=C6BUN1_DESAD
          Length = 380

 Score =  172 bits (435), Expect = 2e-41,   Method: Composition-based stats.
 Identities = 75/371 (20%), Positives = 129/371 (34%), Gaps = 33/371 (8%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDA----QR 56
             FDV I G GP GS  A  LAGK  +V  +DK          K CGGLL   A     +
Sbjct: 3   GKFDVIIAGAGPTGSTAATILAGKGFKVALIDK----AEFPRKKLCGGLLTYKATEVLNK 58

Query: 57  SFIRDGLTLPVDVIANPQIFSVKTVDVAASLT-RNYQRSYININRHAFDLWM-KSLIPAS 114
            F  D   L    I N +           ++        +  ++R  FD ++ +    A 
Sbjct: 59  IFGCDVDCLKKQGIINFESPEYSINYRDYNIRDAESSIPFRFVDRIDFDYFLLQKAANAG 118

Query: 115 VEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRK- 173
            +++     ++   +D +           +    +YL+GADG +S +RR +  D +  + 
Sbjct: 119 AQIFTGEEIKECNYQDAEIK-----TASNRIFKGKYLIGADGVHSTIRRSVPYDKKKWRD 173

Query: 174 -YVAIQQWFAEKHPVPF---YSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTT 229
              A  +   +K   P       ++   +   Y W     G  + G     +      T 
Sbjct: 174 DMAATIEIIFDKKDFPREVAKPELYIGHLRAGYIWVFPAKGKVVTGIGALTRCT----TD 229

Query: 230 LKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFV--CGKDNAFLIGEAAGFISASSLEGIS 287
            K+    F    G           +P  + +F+         L G+AAG +     EGI 
Sbjct: 230 FKKTYMDFLRSQGIANPESMHMQGYPLPYGNFMENPCFGRTLLAGDAAGLVEPLFGEGIF 289

Query: 288 YALDSTDILRSVL------LKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWI 341
           YAL +       +       K P+K             L+   ++  +   + P L+   
Sbjct: 290 YALQTGRYAAESIARGITENKSPDKFYLERLEKYVFPELRYSNRLRWTLFYSQPLLKHMS 349

Query: 342 MRSGVAHIPQL 352
            +     +P++
Sbjct: 350 FKMMFKSMPRI 360


>UniRef50_Q8TMB3 Putative uncharacterized protein n=1 Tax=Methanosarcina acetivorans
           RepID=Q8TMB3_METAC
          Length = 257

 Score =  171 bits (434), Expect = 3e-41,   Method: Composition-based stats.
 Identities = 50/261 (19%), Positives = 99/261 (37%), Gaps = 13/261 (4%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
           + +D+ IIG GPAGS  A  LA   +V+ ++          +K C G+L   +     + 
Sbjct: 3   KQYDITIIGAGPAGSMSAYNLAKHFKVLIVEAHGL----PRNKSCSGILIKKSVDILEKY 58

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKS-LIPASVEVYHD 120
              +P +V   P   +  T+     + R++    +NI R  FD W+    I A  ++   
Sbjct: 59  FDNIPDNVKCTPYETNGITIIDEYMVPRDFPDKGLNILRDKFDYWLVQHAIKAGADLIDH 118

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW 180
           S   K+   ++   +  ++D     I ++ ++  DG +   R       Q  K V  Q++
Sbjct: 119 SRVVKLDENENGVTLTIKSDSV-YKINSKIVIACDGVSGTSRIMTNTPKQ-NKLVTYQKY 176

Query: 181 FAEKHPVPF--YSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTT----LKEKM 234
           +  +  +    +      + +   SW  +K+ + + G           F         K 
Sbjct: 177 YNARASIDRSKFYAYISKNFSEYDSWINTKNNHIVVGTIAKTLTKSKYFHNQFISFLRKE 236

Query: 235 SAFQFQFGKTVKSEKCTVLFP 255
             F+       +S    ++ P
Sbjct: 237 INFEIIKEIKDESWYIPLVIP 257


>UniRef50_Q8DJ25 Tll1404 protein n=7 Tax=Cyanobacteria RepID=Q8DJ25_THEEB
          Length = 378

 Score =  171 bits (432), Expect = 4e-41,   Method: Composition-based stats.
 Identities = 73/340 (21%), Positives = 130/340 (38%), Gaps = 19/340 (5%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQ-VIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +D  ++G GPAG A A  LA + + V+ L+K+         KPCGG ++P  Q  F  D 
Sbjct: 2   YDCIVVGSGPAGGAAAYHLAKRGRRVLVLEKEAL----PRYKPCGGGVSPQVQSWFDFDF 57

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIP-ASVEVYHDS 121
            +  + +     + + +  +         Q     + R  FD ++         E+   +
Sbjct: 58  -SPAISLKVTQMVCTWQGEEAQLLEFPPEQ-PMWMVRRDVFDYFLIQQAQRQGAELRPQT 115

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWF 181
               +    D+W V           TA+YL+G DGA   + + L    + ++  A  +  
Sbjct: 116 PVTGLTWGGDRWQVHT----PSGDFTAQYLIGCDGAKGSMAKWLGFKDRQQRVGAAIEIE 171

Query: 182 AEKHPVPFYSCIFD-NSITNCYSWSISK-DGYFIFGGAYPMKDGQTRFTTLKEKMSAFQF 239
           A        +  FD   + N Y W+  K DGY I  G   +   Q     L+   + +  
Sbjct: 172 AAMPDHSLTAAHFDFGRLHNGYIWNFPKRDGYSIGVGTVALGRKQ----NLRAIGAEYAK 227

Query: 240 QFGKTVKSEKCTVLFPSRWQD-FVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRS 298
            FG      K        WQ        NA L GEAA  +   + EGI  +L +  +   
Sbjct: 228 TFGVDFNQVKVYGHPLYCWQQHQRLHTQNALLAGEAACVVDPFTAEGIRPSLLTGMLAAQ 287

Query: 299 VLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALR 338
            + +       A    +++++ +    ++ ++ L+    R
Sbjct: 288 AIDRALSGDPEALTNYSQQVQQEWGADMIWAKRLSTLFYR 327


>UniRef50_A3CSH0 Geranylgeranyl reductase n=1 Tax=Methanoculleus marisnigri JR1
           RepID=A3CSH0_METMJ
          Length = 403

 Score =  171 bits (432), Expect = 5e-41,   Method: Composition-based stats.
 Identities = 78/365 (21%), Positives = 122/365 (33%), Gaps = 41/365 (11%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
            +D  ++G GPAGS  A  LA     +AL ++    T   +K CGG L+    R   R  
Sbjct: 6   EYDAVVVGGGPAGSTAACLLAEAGHSVALLER---RTYPRNKVCGGCLSQKTVRFLDRVF 62

Query: 63  LTLPVDVIANPQI------FSVKTVDVAASLTRNYQRSYININRHAFDLWMKS-LIPASV 115
            +LPV  +    +           +     LT +         R  +D ++      A  
Sbjct: 63  -SLPVPALRQAGLLDFTGTGYALYIGSRRILTEDLDEPVYFTGRERYDAFLAKMAARAGA 121

Query: 116 EVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKY- 174
           EV+  +    I   D     +  +DG     +AR ++GADG +S VRR L      RK  
Sbjct: 122 EVHTGAEAAGI---DHARRTVTTSDGD--RYSARVIIGADGVHSRVRRTLPQSVVDRKRW 176

Query: 175 ---------VAIQQWFAEKHPVPFYSCIFDNSIT----------NCYSWSISKDGYFIFG 215
                    +AI +  AE           D+ +             Y W        I G
Sbjct: 177 QNNLGWTLELAIPRREAETLVNEDGPIRLDDGLATPHLILAACRWGYGWVFPNREAIIVG 236

Query: 216 GAYPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTV--LFPSRWQDFVCGKDNAFLIGE 273
               +         L++   AF    G +  + +     L P          +   L+G+
Sbjct: 237 IGGLL---SANGGNLRDTFEAFLKSVGLSAFAARKPAGYLLPLGNYIPSPAHEGTVLVGD 293

Query: 274 AAGFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLT 333
           A GF      EGI YA  + ++      +            T  LR +L  ++     L 
Sbjct: 294 AGGFTGPLLGEGIFYAHRTAELAAHAADRHLTAGAPLAATYTALLRRRLIPELRAETALR 353

Query: 334 APALR 338
               R
Sbjct: 354 NFVYR 358


>UniRef50_B8G4M6 Geranylgeranyl reductase n=6 Tax=Chloroflexaceae RepID=B8G4M6_CHLAD
          Length = 421

 Score =  170 bits (431), Expect = 6e-41,   Method: Composition-based stats.
 Identities = 64/336 (19%), Positives = 120/336 (35%), Gaps = 23/336 (6%)

Query: 6   VAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           V I+G    G+  A  L    ++ I ++K+         KPCGG + P A R F      
Sbjct: 5   VLIVGASVGGATAAITLRSFGIETILIEKELVKA-----KPCGGAVPPAAFREFDLPTSL 59

Query: 65  LPVDV-IANPQIFSVKTVDVAASLTRNYQRSYI-NINRHAFDLWMKSLIPASVEVYHDSL 122
           +   V        S +   V  + T   +  Y+  + R  FD +++            + 
Sbjct: 60  IDRKVRQCLIVSPSGQETRVPVAGTVPSEDDYVAMVRREVFDSFLRRRAQERGAELIHAQ 119

Query: 123 CRKIWREDDKWHVIFRA-DGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWF 181
              +  +       +R   G E  + A  ++GADGA S   + L   + + + VA+Q+  
Sbjct: 120 LIGLRVDRRGVEATYRTPSGHEGSVWADVVIGADGAYSPTAKFLGLPN-LPRAVAMQERI 178

Query: 182 AEKHP-----VPFYSCIFDNSI-TNCYSWSISKDGYFIFGGAYPMKDGQTR---FTTLKE 232
                              + +  + Y+W+  K  +   G     + G         LK 
Sbjct: 179 KLPPDKMARWEETADLYLGHEVSPDLYAWAFPKRDHIAVGIGAGPRHGSAAKQLLNNLKR 238

Query: 233 KMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDS 292
           ++ +        ++      + P          D    IG+AAG +  +S EGI +A+ S
Sbjct: 239 RLGSALDGGQVILREAHALPMEP----RPHLAFDRVMFIGDAAGLVVHTSGEGIYWAMKS 294

Query: 293 TDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVK 328
             +    L +  +  + A  R   +   K +G + +
Sbjct: 295 GQMAAQTLAEYLDAPSEANLRTYERRWWKQYGTMYR 330


>UniRef50_D2B4C1 Geranylgeranyl reductase n=4 Tax=Actinomycetales RepID=D2B4C1_STRRD
          Length = 425

 Score =  170 bits (430), Expect = 8e-41,   Method: Composition-based stats.
 Identities = 66/345 (19%), Positives = 123/345 (35%), Gaps = 36/345 (10%)

Query: 5   DVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           DV ++G GPAGS  A  LA   + V+ L+K     T    K CG  L P A +  I  G+
Sbjct: 17  DVIVVGAGPAGSTTAFHLAQAGLDVLLLEK----TTFPREKVCGDGLTPRAVKQLIAMGI 72

Query: 64  TLPVDVIANPQ----IFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYH 119
            +        +    +      ++      +Y    +   R  FD  + +          
Sbjct: 73  DIDAPGWVRNKGLRVVGGGLRFELDWPELSSYPDFGLVRTRQDFDEILAANAVRGGVRLL 132

Query: 120 DSLCRKIWREDDK----WHVIFRADGWEQHITARYLVGADGANSMV--RRHLYPDHQIRK 173
             +       DD+      V+ + DG E    +R +V ADG ++ +     L+       
Sbjct: 133 QGVNVTAPILDDRSGHIVGVVAKKDGEEVSYRSRLVVAADGNSTRISLAMGLHKREDRPM 192

Query: 174 YVAIQQWFAEKHPVPFY--SCIF---DNSITNCYSWSI-SKDGYFIFGGAYPMK----DG 223
            VA++ +F        Y  + +     +++   Y W     DG    G           G
Sbjct: 193 GVAVRTYFESPRHDDDYLETWLELWDGDTLLPGYGWIFGVGDGTSNVGLGLLNTSESFKG 252

Query: 224 QTRFTTLKEKMSAFQFQFGKTVKSEKCTVL---FPSRWQDFVCGKDNAFLIGEAAGFISA 280
                 L+  +     ++G   ++    +     P  +           L+G+A G I+ 
Sbjct: 253 MDYRDLLRRWVKNMPPEWGYVEENMTTPIRGAALPMAFNRQPHYTRGLVLVGDAGGMINP 312

Query: 281 SSLEGISYALDSTDILRSVLLKQP--------EKLNTAYWRATRK 317
            + EGI+YA+++  I    +++          E++  AY +  + 
Sbjct: 313 FNGEGIAYAMETGQIAAETIVQALARTTPAQRERVLRAYPQTLKD 357


>UniRef50_A8ME14 Geranylgeranyl reductase n=1 Tax=Caldivirga maquilingensis IC-167
           RepID=A8ME14_CALMQ
          Length = 362

 Score =  170 bits (430), Expect = 8e-41,   Method: Composition-based stats.
 Identities = 63/302 (20%), Positives = 103/302 (34%), Gaps = 24/302 (7%)

Query: 4   FDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +D+ IIG GPAG+A A   +   ++ + +DK          KPCGG L P         G
Sbjct: 2   YDLIIIGSGPAGNAAALVASRLGVRALIIDKSKH----PRVKPCGGGLTPKTIALSRILG 57

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYINI-NRHAFDLWMKSLIPASVEVYHDS 121
           L L    +   +   V  V  A S    ++   I +  R   D +M +    +   Y + 
Sbjct: 58  LDLSE--VIEHECGEVLVVTHAGSFVMRFKEPMIRVSRRERLDEFMFNEAVNNGVEYVND 115

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWF 181
              ++     K  VI    G      A++++GADGA S V R +    +      +    
Sbjct: 116 EVLRVRETPSKVEVI----GRSSVYEAKWVIGADGAPSRVGRSIGVMPRSNAVALMNIAS 171

Query: 182 AEKHPVPFYSCIFDNS-ITNCYSWSIS--KDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQ 238
                    +CI D + I   Y+W        Y +  G+           +   ++    
Sbjct: 172 GNPIINTGDACILDFTRIKWGYAWLFPLSHGEYDVGLGSALKGRYSNLLLSYVNELG--- 228

Query: 239 FQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRS 298
                 +K  +                    L G+A G     + EGI  A+ S  +   
Sbjct: 229 ------LKPGRLIGHLIPYRPPNSASTRRVMLTGDALGLADPVTGEGIFQAMMSGALAAL 282

Query: 299 VL 300
            L
Sbjct: 283 SL 284


>UniRef50_A8URP5 Putative uncharacterized protein n=2 Tax=Aquificaceae
           RepID=A8URP5_9AQUI
          Length = 387

 Score =  169 bits (429), Expect = 9e-41,   Method: Composition-based stats.
 Identities = 63/345 (18%), Positives = 125/345 (36%), Gaps = 20/345 (5%)

Query: 4   FDVAIIGLGPAGSALARKLAGK-MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +D  ++G GPAG++ AR L+ K ++V+ L+K+         K C G L+    R      
Sbjct: 10  YDAVVVGGGPAGASSARFLSEKGLKVLLLEKRKL----PRFKLCAGCLS---VRITPLLP 62

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVYHDS 121
                +V+   +   +           + +     I+R +FD ++ KS + +  +++ ++
Sbjct: 63  TGWESEVLNTIRGGYLGFRGEKFHHKTSGEPVAYIIDRASFDHFLVKSAVESGADLWEET 122

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWF 181
                  +        R    +  +    L+GADG  + V + L    + + + +++ W 
Sbjct: 123 EFLSFEGDR-----TLRVRTDKGAVETDLLIGADGFYTKVGKQLGYQKR-KFFRSVEFWT 176

Query: 182 AEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQF 241
                      I    +   Y W   K      G A   +  +     LK+ +   +   
Sbjct: 177 EGDLGEEVVIDI--GIVKRGYGWIFPKGDKVSVGLATTGR--ENTLDVLKDYVKRHELLK 232

Query: 242 GKTVKSEKC-TVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVL 300
            K VK  K   + + +   +   GK    L+G++A  +     EGI Y +    +L   +
Sbjct: 233 SKEVKGVKGWMIPYLTSPSEAQLGKGRVMLVGDSANLVDPLLGEGIYYGVLGGKLLAESI 292

Query: 301 LKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSG 345
            + P      Y    R+  +       K   L     R   +  G
Sbjct: 293 TQNPGSPLQTYTDLVRREIIPELVYAGKIARLAYNFQRPAFIMGG 337


>UniRef50_C0GUA1 Geranylgeranyl reductase n=1 Tax=Desulfonatronospira thiodismutans
           ASO3-1 RepID=C0GUA1_9DELT
          Length = 368

 Score =  169 bits (428), Expect = 1e-40,   Method: Composition-based stats.
 Identities = 74/347 (21%), Positives = 139/347 (40%), Gaps = 41/347 (11%)

Query: 4   FDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +DV IIG GPAG+  A  LA   M V  LDKK    +    K C G+L    Q++  +  
Sbjct: 5   YDVIIIGCGPAGATAALLLAAKGMDVAVLDKK----SFPRFKLCAGML---TQKTLDQCS 57

Query: 63  LTLPV--------DVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFD-LWMKSLIPA 113
           L  P         D+I +       +       T + + SY+ ++R ++D LW + +   
Sbjct: 58  LFYPELAHELKKRDIIRHVSSQYAISTGKKRLYTGSSKYSYVLVDRESYDQLWHEKVRET 117

Query: 114 SVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIR- 172
              VY +    ++   + +           +    R+++GADG +S VR+ L  +  +R 
Sbjct: 118 GASVYRE-QIVRVDIPESRVTAK-----NGRVFRGRFILGADGGSSRVRKTLALEKVVRP 171

Query: 173 -----KYVAIQQWFAEKHP-VPFYSCIFDNSITNCYSWSISKDGYFIFG-GAYPMKDGQT 225
                  +A++ + + +    P +  +F   + + Y+WS         G  +  +KDG+ 
Sbjct: 172 PWSKGSALALETFVSRQQAGFPDFPELFTGIVPDGYAWSFPGASRQRLGICSAVVKDGRE 231

Query: 226 RFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEG 285
               + + ++          + E    + P    +   G  N  L+G+AAG       EG
Sbjct: 232 LRKIMLDLLAGQGVHLD---EKEIRGHVLPYGDYEKTPGFQNILLLGDAAGMADPLLGEG 288

Query: 286 ISYALDSTDILRSVLL-------KQPEKLNTAYWRATRKLRLKLFGK 325
           I YA  +  +    +        +  +  ++      R +R+K F +
Sbjct: 289 IYYAHATGGLAARAVEECWSRNDRTADVYSSLLSDIIRDMRIKWFMR 335


>UniRef50_UPI0001C15A6F geranylgeranyl reductase n=2 Tax=Nostocaceae RepID=UPI0001C15A6F
          Length = 404

 Score =  168 bits (425), Expect = 3e-40,   Method: Composition-based stats.
 Identities = 62/346 (17%), Positives = 112/346 (32%), Gaps = 40/346 (11%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M ++DV + G GPAG+  A   A   ++V  ++K          K CGG +         
Sbjct: 1   MLNYDVIVCGAGPAGTTAAWMAAKTGLKVALIEKY----PLPRHKTCGGGMPAVLGNLLP 56

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRS-----YININRHAFDLWM-KSLIPA 113
                  V    N    + K  D       N   S        + R  FD  + +    A
Sbjct: 57  DLVPEAVVACQVNYMRHTWK-FDHPILGAINPPGSEPELKLWMVQRSVFDNALARQAAQA 115

Query: 114 SVEVYHDSLCRKIWREDDKWHVIFRA-------DGWEQHITARYLVGADGANSMVRRHLY 166
             ++      + +  +     V  R+        G E    A Y++GADGAN +  +   
Sbjct: 116 GADLRDGLAVKSLEMDSHGVIVRARSFKSDSGIGGGEFVAYAPYVIGADGANGITAKIAN 175

Query: 167 PDHQIRKYVAIQQWFAE-------KHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYP 219
              +    +A++  +         K   P    +   ++ N Y W   K+ +   G    
Sbjct: 176 LRRERTMALAMEVEYPYNWTQDHPKDLRPDVIHLEYGAVPNGYGWIFPKEDHLNVGAGLF 235

Query: 220 MKDGQ------TRFTTLKEKMSAFQFQFGKTVKSEKCT---VLFPSRWQDFVCGK--DNA 268
             D +      +    L++ +  +      +   E         P       C       
Sbjct: 236 RPDRRDCRSDHSIRAQLQQAICQYLDFMDISYNPELIRFHGHPLPIWDGREKCHTPDGKI 295

Query: 269 FLIGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRA 314
            L G+AAG I+    +GI +A+ S  +    +        ++Y + 
Sbjct: 296 LLAGDAAGLINPFFGDGILHAVKSGMLAAECVATSA---TSSYTQR 338


>UniRef50_Q648X7 Geranylgeranyl reductase n=4 Tax=environmental samples
           RepID=Q648X7_9ARCH
          Length = 420

 Score =  168 bits (425), Expect = 3e-40,   Method: Composition-based stats.
 Identities = 67/340 (19%), Positives = 122/340 (35%), Gaps = 18/340 (5%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           E +DV ++G GPAGS  A+  A   + V+ +++  + G       CG  ++ + +R F+ 
Sbjct: 28  EKYDVVVVGAGPAGSITAKTAAERGLDVLLIERNPEIG---VPVKCGECVSKEIER-FVD 83

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVYH 119
                    I     +      V  S+    +  Y+ + R  FD  + +    A  EV  
Sbjct: 84  IDRRWVCAGIRGTITYGPDGTKVILSVEGAEEVGYV-LERKIFDKCLAQEAARAGAEVRV 142

Query: 120 DSLCRKIWREDDKWHVIFRADGW---EQHITARYLVGADGANSMVRRHLYPDHQIR---- 172
            +    +  +      ++        +  I+A  +VGADG  S V +    D  +     
Sbjct: 143 KTQVYGVVNDGGYAKGVYARTAEAEGDIRISADVVVGADGVESRVGKWGGIDTTLHLADV 202

Query: 173 KYVAIQQWFAEKHPVPFYSCIF-DNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLK 231
              A       +    +    F D+     Y W   K  +    G     D        +
Sbjct: 203 ATCAQFLMCDIEVNNEYCEIFFGDDVAPKGYGWIFPKGDHCANVGLGIGGDVSNENHCAR 262

Query: 232 EKMSAF-QFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYAL 290
           + ++AF   +F       +     P     +    +   L+G+AA  ++  +  GI  A+
Sbjct: 263 DYLNAFVGGKFPNGKIIAEMYGAVPLSGPVYETVANGLILVGDAARHVNPITGGGILEAM 322

Query: 291 DSTDILRSVLLK--QPEKLNTAYWRATRKLRLKLFGKIVK 328
              +I   V+ K  Q    +    R   K   K FGK++K
Sbjct: 323 QGGEIAGDVIAKAVQENDFSKRRLREYEKRWRKEFGKVLK 362


>UniRef50_B8HM17 Geranylgeranyl reductase n=1 Tax=Cyanothece sp. PCC 7425
           RepID=B8HM17_CYAP4
          Length = 376

 Score =  167 bits (423), Expect = 5e-40,   Method: Composition-based stats.
 Identities = 65/346 (18%), Positives = 123/346 (35%), Gaps = 22/346 (6%)

Query: 3   HFDVAIIGLGPAGSALARKL-AGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            +D+ I+G GPAG+ LA       ++ + LDK          K CG  +     +     
Sbjct: 4   EYDLIIVGGGPAGTTLALFAHRAGLKTLLLDK----ARFPRDKICGDAIILPGIKILEEL 59

Query: 62  GLTLPVDVIANPQIFSVKT-VDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD 120
            LT    +   P  +SV       +   +      + + R  FD  + +   A V+    
Sbjct: 60  ELT--AALHQGPHSYSVNFHCFTESEHLQAPGSHCLMVKRLYFDHVLFTAAKAVVDTCEG 117

Query: 121 SLCRKIWREDD-KWHVIFR-ADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKY--VA 176
           +   ++ +++   + V  R  +  E   TA+ +VGADG  S+V +         ++  VA
Sbjct: 118 AEVEQLLQQEGQVYGVRGRLQNQEEFEFTAKVVVGADGCGSVVAKKAGVFKFEPQHYGVA 177

Query: 177 IQQWFAEKHPVPFYSCI---FDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEK 233
            + ++    P+P+   I   +       Y W    D   +  G             L ++
Sbjct: 178 TRAYYRHL-PLPYGKAIEFYYFQECLPGYLWIFPVDQETVNVGVGVEPSPNQALPKLHQQ 236

Query: 234 MSA---FQFQFGKTVKSEKCTV-LFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYA 289
           +      + +F +     +      P   +      +   LIG+AAG I     +GI  A
Sbjct: 237 LLESPLLKSRFAEAELIGQIQAWSLPLASKQRKIHGNGFILIGDAAGLIDPFWGDGIDKA 296

Query: 290 LDSTDILRSVLLK--QPEKLNTAYWRATRKLRLKLFGKIVKSRCLT 333
           + S  +   VL +  + +  + A  +          G   +  C  
Sbjct: 297 MLSAKVAAQVLAEVCRGQDYSAAALQDYPDSLWSQLGAKFQYSCRL 342


>UniRef50_C6CUN6 Monooxygenase FAD-binding n=1 Tax=Paenibacillus sp. JDR-2
           RepID=C6CUN6_PAESJ
          Length = 395

 Score =  166 bits (421), Expect = 8e-40,   Method: Composition-based stats.
 Identities = 84/381 (22%), Positives = 146/381 (38%), Gaps = 62/381 (16%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M  +DV ++G GP+GSA A+ LA    +++ LD +         KPCG  L P A  +  
Sbjct: 1   MNSYDVIVVGAGPSGSASAKMLAASGVRILMLDAEA----FPRRKPCGESLNPGAVAALG 56

Query: 60  R----DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYINI--NRHAFDLWMKSLIPA 113
           R      +    D  ++P I   K     ASL   Y   +  +   R   DLW+      
Sbjct: 57  RITGYSHVQEAFDFTSSP-IQGWKVSSGRASLEAVYPEGHYGVGCRREQVDLWLAEQASR 115

Query: 114 SVEVYHD--SLCRKIWREDDKWHVIFRA-DGWEQHITARYLVGADGANSMVRRHLYPDHQ 170
           +  V+     + R IW  +    VI R+ +G    I A  ++G+DG  S+V R    + +
Sbjct: 116 AGAVFEQRTKVERLIWEGERVAGVIARSPEGKPMSIRASLVIGSDGLRSVVAR----NAK 171

Query: 171 IRKYVAIQQ--WFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFT 228
           + +Y ++++  + A  + V          +        + +G  I  G  P+  G    T
Sbjct: 172 VNRYGSLRKAAFTARLNGV--------RGLNGRVELFTAGEGKVI--GLAPIGAGLANMT 221

Query: 229 TL----KEKMSAFQFQFGKTVKSEKCTVLFPSRWQD-------FVCGK----------DN 267
            +    K    A + + G  ++  +       R +D         CG             
Sbjct: 222 VVLGSAKAASLADKDRLGIVLREARAVPELTERLRDAEIEDGVLACGPFDRPVIPHDIAG 281

Query: 268 AFLIGEAAGFISASSLEGISYALDSTDILRSVL-----LKQPEKLNT----AYWRATRKL 318
             L+G+AAG+    + +GI  AL S ++    +      + P+ L               
Sbjct: 282 MVLLGDAAGYYDPLTGQGIYRALRSAELAAPAIVQTLQTRDPDPLRQYRIANLAEFATGT 341

Query: 319 RLK-LFGKIVKSRCLTAPALR 338
           RL+ +  ++ +   L   ALR
Sbjct: 342 RLQHIIERLTRHPLLWRSALR 362


>UniRef50_A0LRI0 Geranylgeranyl reductase n=38 Tax=Actinomycetales
           RepID=A0LRI0_ACIC1
          Length = 445

 Score =  166 bits (421), Expect = 8e-40,   Method: Composition-based stats.
 Identities = 72/383 (18%), Positives = 137/383 (35%), Gaps = 40/383 (10%)

Query: 5   DVAIIGLGPAGSA-LARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           DV ++G GPAGS   A      + V+ L+K          K CG  L P A R  +R G+
Sbjct: 34  DVVVVGAGPAGSTTAAYLAQAGVDVVVLEKSA----FPREKVCGDGLTPRAVRQLVRLGI 89

Query: 64  TL-----PVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVY 118
                   +       +     +++      ++    +   R  FD  +         V 
Sbjct: 90  DTSAQAGWLRNKGLRILGGGMRLELPWPELASFPDYGLVRPRTDFDQLLARHAAKLGAVV 149

Query: 119 HDSLCRKI----WREDDKWHVIFRADGW-EQHITARYLVGADGANSMVRRHLYPDHQIRK 173
           H+           R      V+  A+G     +    +V ADG +  +   +  D   R+
Sbjct: 150 HERTPVSAPLIDDRTGRVVGVVATAEGERPLVVRGSVVVAADGNSGRLALAVGRDRLPRR 209

Query: 174 --YVAIQQWFAEKHPVPFY--SCIF---DNSITNCYSWSI-SKDGYFIFGGAYPMKDGQT 225
              VA ++++A +     +  S +       +   Y W     DG    G          
Sbjct: 210 PMGVAYRRYYASRRHDDTWLESWLELRDGGRLLPGYGWIFGMGDGTSNVGVGILNTSSAF 269

Query: 226 RFTTLKEKM----SAFQFQFGKTVKSEKCTVL---FPSRWQDFVCGKDNAFLIGEAAGFI 278
           R    +  +    +    ++G T ++ +  +     P  +       D   L+G+AAG I
Sbjct: 270 RNIDYRALLRRWVAGMPAEWGITEETAQGPIRGAALPMGFTRKPQYADGLLLVGDAAGMI 329

Query: 279 SASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKS--------- 329
           +  + EGI+YA++S      ++++   K   A    T +   ++  +             
Sbjct: 330 NPCNGEGIAYAMESGAAAAEIIVQALAKPTGAARERTLRSYPRVLAEQYGGYYTLGRWFV 389

Query: 330 RCLTAPALRKWIMRSGVAHIPQL 352
           + +  P + +++ R G+ H PQL
Sbjct: 390 QLIGKPGVMRFLTRHGLPH-PQL 411


>UniRef50_B3QWR4 Geranylgeranyl reductase n=1 Tax=Chloroherpeton thalassium ATCC
           35110 RepID=B3QWR4_CHLT3
          Length = 382

 Score =  166 bits (420), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 70/369 (18%), Positives = 132/369 (35%), Gaps = 30/369 (8%)

Query: 1   MEHFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M+  +V ++G GPAGS  A  LA     V+ LDK          K CG  +   A     
Sbjct: 1   MQT-EVLVVGAGPAGSTAAAILAQKGYDVLILDKTE----FPRQKACGDGIPHSAIALLD 55

Query: 60  RDGLTLPVDVIANPQIFSVKTVD---VAASLTRNYQRSYININRHAFDLWMKS-LIPASV 115
           + GL          +I            +S+    + ++   +R  FD  + S  + +  
Sbjct: 56  QLGLHDQFRNTKRNEITGATIHSPRGQQSSINFRMRDNFFIQSRSVFDHTLFSHALTSGA 115

Query: 116 EVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKY- 174
           +         I  +     V  R    E+ I A   + ADG +S +   L  + Q+ K+ 
Sbjct: 116 KFLKAKALEPILNQGKVVGVKARVQDEEKRIFAPITIAADGVDSAIAAPLRREKQLAKHR 175

Query: 175 -VAIQQWFAEKHPVPF-YSCIFDNSITNCYSWSIS-KDGYFIFGGAYPMKDGQTRFTTLK 231
            ++++ + +  +  P      F   I   Y W     +     G    M        ++K
Sbjct: 176 AISLRGYISGLNLNPRTVEGFFPKEIVPGYLWIFPLGEKEANIGLGMRMDKYAKVGMSMK 235

Query: 232 EKMSAF--------QFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSL 283
           + +  F        + +    +   + + +  +  +      D A L+G+AA  +S  + 
Sbjct: 236 QVLQNFLASPEIKARLEPNWQLSDVRASPMNFASQKGIQLAYDGAVLVGDAASLVSPLTG 295

Query: 284 EGISYALDSTDILRSVLLKQ------PEKLNTAYWRA-TRKLRLKL-FGKIVKSRCLTAP 335
            GI  A+ S       +          EK  + Y R     +R ++    +V++   T P
Sbjct: 296 GGIYNAMFSAKTAAETIHDAFQKNDFSEKKLSEYERRCWAAIRYEMKITYVVQNAISTFP 355

Query: 336 ALRKWIMRS 344
            L + +M+ 
Sbjct: 356 FLIEGLMKF 364


>UniRef50_B1LSG8 Geranylgeranyl reductase n=27 Tax=Proteobacteria RepID=B1LSG8_METRJ
          Length = 408

 Score =  165 bits (418), Expect = 2e-39,   Method: Composition-based stats.
 Identities = 78/353 (22%), Positives = 125/353 (35%), Gaps = 34/353 (9%)

Query: 21  KLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSF-IRDGLTLPVDVIANPQIFSVK 79
                  V+ LDK       G  KPCGG + P   R F I D L +     A     S K
Sbjct: 32  LARAGHAVLLLDKP------GRIKPCGGAIPPRLIRDFAIPDALLVAKIRSARMVAPSGK 85

Query: 80  TVDVAASLTRNYQRSYIN-INRHAFDLWMKSLIPASVEVYHDSLCRKIWREDDKWHVIFR 138
           TVD+           ++  ++R  FD W+++    +      +   +I R DD   ++  
Sbjct: 86  TVDMPV------GEGFVGMVDREHFDPWLRARAAEAGADLRAAAFERITRPDDGPPLVHF 139

Query: 139 ADGWEQ-----HITARYLVGADGANSMVRRHLYPDH-QIRKYVAIQQWFAEKHPVPFYSC 192
             G         + AR +VGADGA S V R   P H ++R+  A  +           + 
Sbjct: 140 TTGAGTGLARHAVRARLVVGADGACSPVGRAEVPGHARMRQVFAYHEILRVPEAGAPGAG 199

Query: 193 IFDNSI----------TNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFG 242
             + +            + YSW          G     K    R + ++    A      
Sbjct: 200 SVEATRCDVYYQGRHSPDFYSWIFPHGDTLSIGTGSARKGFSLRSS-IRALRVATGLDGA 258

Query: 243 KTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLK 302
           +TV+ E      P +         +  L G+AAG ++ +S EGI YA+    +       
Sbjct: 259 ETVRREGAP--LPLKPLKRWDNGRDVLLAGDAAGVVAPASGEGIYYAMLGGRLSAEAAAA 316

Query: 303 QPEKLNTAYWRATRKLRLKLFGKIV-KSRCLTAPALRKWIMRSGVAHIPQLKD 354
             E  +       R+  +KL G++      +     R   +R     I + KD
Sbjct: 317 FLETGDARALGRARRRFMKLHGRVFWILGMMQWVWYRSDGLRERFVSICRDKD 369


>UniRef50_A8LAV2 Geranylgeranyl reductase n=5 Tax=Actinomycetales RepID=A8LAV2_FRASN
          Length = 409

 Score =  165 bits (417), Expect = 2e-39,   Method: Composition-based stats.
 Identities = 80/358 (22%), Positives = 124/358 (34%), Gaps = 24/358 (6%)

Query: 5   DVAIIGLGPAGSALARK---LAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
           D+ ++G GPAGS+ A +   L    +V+ +D           K CG  +AP         
Sbjct: 23  DLLVVGGGPAGSSAALRALQLRPDARVVIVD----AADFPRDKTCGDGIAPHGVDVLRAL 78

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDS 121
           G+T             ++T    A +    +R+   I R  FD  + +   A    +   
Sbjct: 79  GITDATSGYRPVDRMRLRT-PGGAEVATPSERATHVIPREVFDARLVAAARARGAEFLRR 137

Query: 122 LCRKIWRE-DDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLY--PDHQIRKYVAIQ 178
             R +          +   DG    + AR +VGADGANS VRR L   P+      +A++
Sbjct: 138 RVRSLEVTAGGGGEPVVTVDGG--VLRARVVVGADGANSTVRRALGIAPNPPEGLAIAVR 195

Query: 179 QWFAEK--HPVPFYSCIFDNSITNCYSWSIS-KDGYFIFGGAYPMKDGQTRFTTLKEKMS 235
            +         P       +     Y+WS    DG    G        +   TT K  + 
Sbjct: 196 AYADAPKDDRPPEQLIEMTDEGWPAYAWSFPIGDGRANIGYGMLRSRLRAAGTTPKAVLH 255

Query: 236 AFQFQFGKTVKSEKCT---VLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDS 292
               +      + + T      P              L G+AA  I+  + EGI YAL S
Sbjct: 256 GTLARLLPDTPAYEGTLRAHHLPLSTHRPRLPDGPVLLAGDAASLINPLTGEGIYYALLS 315

Query: 293 TDILRSVLLKQP-EKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALR-KWIMRSGVAH 348
             +     +  P      AY RA       L   +  +  L   A R + +M + V  
Sbjct: 316 GSLAGQAAITDPGPAAGRAYRRALDGE---LGRHLRHTSLLAGLAGRHRPLMDAAVRS 370


>UniRef50_C5A6E5 Digeranylgeranylglycerophospholipid reductase n=9
           Tax=Thermococcaceae RepID=GGR_THEGJ
          Length = 395

 Score =  164 bits (414), Expect = 5e-39,   Method: Composition-based stats.
 Identities = 67/340 (19%), Positives = 122/340 (35%), Gaps = 22/340 (6%)

Query: 3   HFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            +DV ++G G AG  +AR +A     V+ +DKK   GT    K C   ++    + F + 
Sbjct: 4   KYDVVVVGAGIAGPIVARNVARAGFSVLLIDKKWAIGT---PKQCAEGIS---IKVFEKY 57

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQR-SYININRHAFDLWMKS-LIPASVEVYH 119
            +      I      +         L   Y+  S + + R  FD  +      A  +V  
Sbjct: 58  DIPYDKRFINREIYGAKLYSPSGYELEMRYKDVSGVILERKVFDKMLAYYAAKAGADVLA 117

Query: 120 DSLCRKIWREDDKW-HVIFRADGWEQHITARYLVGADGANSMVRRH-----LYPDHQIRK 173
            +    + R+D K   +  + +     I A  +V ADG  S + R        P H+   
Sbjct: 118 RTEALDVIRKDGKVVGIKAKHEDEPIEIYADVIVAADGVESTIARKAGINTYAPPHEFDS 177

Query: 174 YVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKD-GYFIFGGAYPMKDGQTRFTTLKE 232
               +       P   +    +      Y W   KD      G      + QT    L +
Sbjct: 178 SYEYEMLIEGFDPDLIHLWFGNEIAPRGYVWVFPKDEDRANVGIGINSDNPQTAKYYLDK 237

Query: 233 KMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDS 292
            +        K ++     V      ++ V  K+N  ++G+AA  ++     G++ A+++
Sbjct: 238 WLKENNIPAKKLLEINVGVVPVGGFVKELV--KNNVLVVGDAARQVNPMHGGGMAEAMEA 295

Query: 293 TDILRSVLLKQPEKLN----TAYWRATRKLRLKLFGKIVK 328
             I    ++K  E+ N      Y +   +   K   K++K
Sbjct: 296 GTIASKWIVKALEEENLSLLQNYTKEWWETDGKRLEKVLK 335


>UniRef50_O26377 Digeranylgeranylglycerophospholipid reductase 1 n=2
           Tax=Methanobacteriaceae RepID=GGR1_METTH
          Length = 397

 Score =  163 bits (412), Expect = 9e-39,   Method: Composition-based stats.
 Identities = 68/329 (20%), Positives = 114/329 (34%), Gaps = 15/329 (4%)

Query: 3   HFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSF-IR 60
             DV +IG GPAGS  A+  A G   V+ +DKK + G     K C   ++     S  I 
Sbjct: 7   EVDVLVIGAGPAGSTAAKHAALGGADVLLIDKKSEIGA---PKRCAEGVSIGGLESLGIE 63

Query: 61  DGLTLPVDVIANPQIFSVKTVDVA-ASLTRNYQRSYININRHAFDLWMK-SLIPASVEVY 118
                    +   ++ S    DV   S       +   + R  FD +M      A   + 
Sbjct: 64  PNPRWITKKLDGVRMVSPNGTDVWLTSDKVELPEAGYILERKVFDKFMAMDAARAGSRIM 123

Query: 119 HDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRH--LYPDHQIRKYVA 176
             ++   + R DD + V     G +  I AR ++ ADG  S V R   L    + +   +
Sbjct: 124 VKTIATGMERTDDGYLVSAECMGEKFEIKARIVIAADGPESRVARWAGLNTATRPKDMES 183

Query: 177 IQQWFAEKHPVPFYSCI---FDNSITNCYSWSIS-KDGYFIFG-GAYPMKDGQTRFTTLK 231
             Q+      +   +CI   F +     Y+  I   D     G G    +  ++ +  L 
Sbjct: 184 AAQFEMVGVEMEDNNCIEFYFGSVAPGGYALDIPEGDDIANVGLGVLSTETDKSAYEHLL 243

Query: 232 EKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALD 291
           E + +                  P          D+  ++G+AAG ++  +  GI   + 
Sbjct: 244 EFVESCPATRNAQPVELNIGGD-PVGGMPKKLVADSLMVVGDAAGQVNPLTGGGIISGMK 302

Query: 292 STDILRSVLLKQPEKLNTAYWRATRKLRL 320
              +   V      + +    R     RL
Sbjct: 303 GGMLAGQVAAAAVSEGDVTARRLGEYERL 331


>UniRef50_C9RJJ2 Geranylgeranyl reductase n=1 Tax=Fibrobacter succinogenes subsp.
           succinogenes S85 RepID=C9RJJ2_FIBSS
          Length = 395

 Score =  163 bits (411), Expect = 1e-38,   Method: Composition-based stats.
 Identities = 63/353 (17%), Positives = 117/353 (33%), Gaps = 25/353 (7%)

Query: 2   EHFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
             +DV +IG GP GS  AR L+    +V+ L+K+ + G       CG             
Sbjct: 5   NEYDVVVIGAGPGGSVAARNLSRAGHKVLLLEKREKIGYPVR---CGEASTK--LSDLQT 59

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKS-LIPASVEVYH 119
            G  +  D I               ++    + + I +NR  FD W+        VEV  
Sbjct: 60  YGP-IDEDCIETIINGLYIYGPNGVNIDLAQKGTGIMLNREKFDPWLAHLAANDGVEVVT 118

Query: 120 DSLCRKIWREDDKWHVIFRADGWE-----QHITARYLVGADGANSMVRRHLYPD---HQI 171
            +    +   +    ++    G       + + A+ ++ ADG  S + R +  D      
Sbjct: 119 RARAEFVGDVESGTRLVRVKLGEGAGETTEEVRAKMVIAADGVESRIGRQVGLDCLQKPA 178

Query: 172 RKYVAIQQWFAEKHPVPFYSCIFDNS--ITNCYSWSIS--KDGYFIFGGAYPMKDG-QTR 226
                +          P Y   +     I + Y WS    K     FG  + + +   + 
Sbjct: 179 FTCTGVDIQVQGILTKPDYLTFWQGHDFINDGYIWSFPKVKSNVTNFGAGFLISNNHGSN 238

Query: 227 FTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGI 286
              +  +     F   +        +   S  +D+    D   L+G+AA   +  +  GI
Sbjct: 239 VLDITMEWLYKLFPGAQINHVVGGVIPVSSVLKDYTL--DRFALVGDAAHHTNPLTGGGI 296

Query: 287 SYALDSTDILRSVLLKQPE--KLNTAYWRATRKLRLKLFGKIVKSRCLTAPAL 337
           + A+ +       + +  E   L+  + +   K     FG++          L
Sbjct: 297 AAAMRAGRFCAQTVHEGFECGNLSKEFLKTYEKRCYDYFGRMHDFEYKFRRFL 349


>UniRef50_B3QNV5 Geranylgeranyl reductase n=4 Tax=Chlorobiaceae RepID=B3QNV5_CHLP8
          Length = 399

 Score =  162 bits (410), Expect = 2e-38,   Method: Composition-based stats.
 Identities = 78/374 (20%), Positives = 133/374 (35%), Gaps = 35/374 (9%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           M+ FDV I G GPAG   A  LA K   +AL  K Q       K CG  + P + R    
Sbjct: 1   MKPFDVVISGAGPAGCTAALSLARKGLRVALIDKAQ---FPRDKTCGDGVTPASVRLLEE 57

Query: 61  DGLTL-------PVDVIANPQIFSVK--TVDVAASLTRNYQRSYININRHAFDLWMKSLI 111
            G+         P+ V     +FS     V    S T +       I R   D    + +
Sbjct: 58  LGVVEVVRQRVGPLTVFKGITLFSPDGAVVQGRLSQTGDRSSESYVIPRSLLDDCFVTCV 117

Query: 112 PAS--VEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDH 169
            A   +  + ++  R++    D         G E     + +V ADG  S +   L   +
Sbjct: 118 KAHESISFFDNTESRELIINGDSAR-GLSTSGGE--FYGKCIVAADGVYSPIAAQLGLLN 174

Query: 170 --QIRKYVAIQQWFAEKHPVPFYSCI-FDNSITNCYSWSIS-KDGYFIFGGAYPMKDGQT 225
             + ++  A++ +F+  + +     + +DN I   Y W     +     G     +  + 
Sbjct: 175 RQKEQQGFAMRAYFSNVNGLSDSIELHYDNLILPGYGWVFPAGEKRANIGVGIMTRFKEP 234

Query: 226 R-FTTLKEKMSAFQFQFGKTVKSE----KCTVLFPSRWQDFV--CGKDNAFLIGEAAGFI 278
           R    + ++  A        +K           +P  +  F     + N  L G+A  F+
Sbjct: 235 RGLKNMFKRFVAENPVVSSKLKDAAMEPGTLKAWPLPFGSFRGMRSQRNVLLAGDAGSFV 294

Query: 279 SASSLEGISYALDSTDILRSVLLKQPEKLNTA-----YWRATRKLRLKLFGKIVKSRCLT 333
              S EGI YA+ S       ++K   + + A     Y +  RK     F +      L 
Sbjct: 295 DPLSGEGIFYAIKSGQFAADAIVKALAENDRAQAGAFYEKLWRKAF--EFDEFSVGYFLQ 352

Query: 334 APALRKWIMRSGVA 347
                +++M + + 
Sbjct: 353 TMLNSRFLMETLLQ 366


>UniRef50_Q31QX9 Geranylgeranyl reductase n=2 Tax=Synechococcus elongatus
           RepID=Q31QX9_SYNE7
          Length = 376

 Score =  162 bits (409), Expect = 2e-38,   Method: Composition-based stats.
 Identities = 65/302 (21%), Positives = 109/302 (36%), Gaps = 15/302 (4%)

Query: 5   DVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           D  ++G GPAG + A  LA + + + L ++ Q       K C G ++P   R F    L 
Sbjct: 3   DCIVVGAGPAGGSAAYHLARRDRQVLLLEQAQL---PRQKACAGGVSPQVARWFD-CDLR 58

Query: 65  LPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVYHDSLC 123
             VD   +   F+ K  D         +  +  + R  FD ++ +        +   +  
Sbjct: 59  SVVDHGVDRLRFTWKLGD-PVEAELPSEEPFWMVRRDRFDHFLVEQAANLGARIEDGAAV 117

Query: 124 RKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAE 183
             +  E D W V       ++   +R L+ ADGA   + + L    Q R+Y    +    
Sbjct: 118 TAVSAEGDGWLVTV----GDRAYRSRTLIAADGARGPLAQWLGFPSQKRRYAQACELDVP 173

Query: 184 KHPVPFYSCIF-DNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFG 242
               P  +  F    + N Y W   K   +  G      +  T F  L   +  +   FG
Sbjct: 174 LPARPDSTAHFEFGLVRNGYIWVFPKSDGYSIGIGTFRGNDATDFRGL---LETYLAGFG 230

Query: 243 KTVKSEKCTVLFPSRW-QDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLL 301
            +   ++        W       + +A L+GEAA      + EGI  AL S       + 
Sbjct: 231 VSADLDRIVPHPLCVWDGSQPLHRGSALLVGEAASLTDPFTAEGIRPALLSGMRAAEAID 290

Query: 302 KQ 303
           + 
Sbjct: 291 RA 292


>UniRef50_Q12YW2 Digeranylgeranylglycerophospholipid reductase 1 n=8
           Tax=Euryarchaeota RepID=GGR1_METBU
          Length = 408

 Score =  161 bits (408), Expect = 3e-38,   Method: Composition-based stats.
 Identities = 64/341 (18%), Positives = 116/341 (34%), Gaps = 21/341 (6%)

Query: 3   HFDVAIIGLGPAGSALARKLAGK-MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            +D+ ++G GPAGS  A   A K + V+ L+K+ + G       C   +     R  I  
Sbjct: 4   QYDLVVVGAGPAGSIAATTAAKKGLSVLMLEKRQEIGEPVR---CAEGVGKKRLRQHIEL 60

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLI-PASVEVYHD 120
                   +++ +I S     +  +           ++R  FD  +  L   A V++   
Sbjct: 61  DEKWLCGEVSSAKIISPNGTTLTMAEEDAGSEVGYVLDRKIFDRTLVELSGEAGVDIMVK 120

Query: 121 SLCRKIWREDDKW-HVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYV--AI 177
           +    +  E++    V     G    I ++ ++GADG  S V R    D  ++       
Sbjct: 121 ARVTGLIIEENTVCGVEMMHLGKTYSIRSKLVIGADGVESKVGRWAGIDTSLKPSHIETC 180

Query: 178 QQWFAEKHPVPFYSCIF---DNSITNCYSWSISK-DGYFIFG-GAYPMKDGQTRFTTLKE 232
            Q+      +   SC F   +      Y W   K +     G G    + G+ +      
Sbjct: 181 AQFLVSGVDIDQSSCYFYMGNKVAPGGYVWVFPKGNNMANVGIGILGSRAGEKKPIEYLT 240

Query: 233 KMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDS 292
                 +  G  ++     V  P+         +   L+G+AA      +  GIS A+D+
Sbjct: 241 DFVEANYPNGSIIEQVAGAV--PASGPIEKTIANGLMLVGDAARQSDPFTGGGISNAMDA 298

Query: 293 TDILRSVLLKQ------PEKLNTAYWRATRKLRLKLFGKIV 327
                 V  +        EK+   Y +  R          +
Sbjct: 299 GLYAGEVAAEAIAQDDVSEKILQKYEKRWRGSFGNEIANNL 339


>UniRef50_D1CHF7 Geranylgeranyl reductase n=1 Tax=Thermobaculum terrenum ATCC
           BAA-798 RepID=D1CHF7_THET1
          Length = 413

 Score =  161 bits (407), Expect = 4e-38,   Method: Composition-based stats.
 Identities = 78/353 (22%), Positives = 119/353 (33%), Gaps = 21/353 (5%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
             +DV ++G GPAGSA A +LA    +V+ LDK          K CG  L P A      
Sbjct: 25  GKYDVVVVGAGPAGSACAWELARHGVRVLLLDKSE----FPRDKTCGDGLTPRAVSVLEG 80

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQ-RSYININRHAFDLWMKSLIPASVEVYH 119
            GL   V  +               S T     R  + + R   D  +     +    + 
Sbjct: 81  MGLAREVAGMGGRVSQVRVVGPGGTSTTLGMPGRGGLVVPRLRLDDALLRRATSVGAEFE 140

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMV-RRHLYPDHQIRKYVAIQ 178
                +    + +  ++   DG    + AR +V A GA+  +  R      + R   A +
Sbjct: 141 APARAEAVELEGQHALVRLEDGRG--VRARMVVVATGASPRLLERSGLVAARPRLLAASR 198

Query: 179 QWFAEKHP-VPFYSCIFDNSITNCYSWSIS-KDGYFIFG-GAYPMKDGQTRFTTLKEKMS 235
            +F      V      F       Y W      G F  G G     +G T     +    
Sbjct: 199 AYFECPAAQVEEMVFSFQGVTLPGYGWIFPLGGGRFNVGAGVLARHEGSTARKEFEAFTR 258

Query: 236 AFQ-FQFGKTVKSEKCTVLFPSR--WQDFVCGKDNAFLIGEAAGFISASSLEGISYALDS 292
           +    +     + E     FP R  +           ++GEAAG ++  + EGI YAL+S
Sbjct: 259 SRLCSRLLPGARREGPVRGFPLRTDFLRSRLWAPGVVMVGEAAGLVNPLTGEGIDYALES 318

Query: 293 TDILR---SVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIM 342
             I       +L + E    AY R  R    +LF        L      +  +
Sbjct: 319 GVIAGRHVREMLSRGEIEARAYERELRSRFSELF---RTCERLRWLCRSRLAV 368


>UniRef50_A8UYA2 Putative uncharacterized protein n=2 Tax=Aquificaceae
           RepID=A8UYA2_9AQUI
          Length = 345

 Score =  161 bits (406), Expect = 4e-38,   Method: Composition-based stats.
 Identities = 62/323 (19%), Positives = 106/323 (32%), Gaps = 18/323 (5%)

Query: 3   HFDVAIIGLGPAGSALARKLAGK-MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            +DV I+G GPAG+  A  L+   ++V+ +D K   G       C   +    +  F   
Sbjct: 2   KYDVLIVGSGPAGATAAYILSRNDVRVLLVDIKRAPG---VPVQCAEFVPIQLKHKFPEF 58

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDS 121
               P DV+A      V        ++   Q     ++R  FD  +              
Sbjct: 59  F---PKDVVAQEVRDMVHFTPWGEVVSM--QSEGYVLHRDRFDRGIVERALKGGTELRLR 113

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWF 181
                + ED K  +          + A  ++GADG  S V R L  +H        Q  F
Sbjct: 114 TVFLGF-EDGKVWLEHIDTRKRYAVEAELVIGADGPRSRVAR-LTGEHTGSFLATAQFTF 171

Query: 182 AEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQF 241
             +  V      F + I   Y W   K      G             +L+  ++    + 
Sbjct: 172 PLRERVSDLLIYFRDYIPGGYGWVFPKGELANVGVGIDPHYPVNVMESLRRLVAELTSEG 231

Query: 242 GKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLL 301
               +    T  +          + N  L+G+A GF    +  GI+ A+ +  +    +L
Sbjct: 232 VVGKEVLGRTGGWIPAEGVKRPLRGNVVLVGDAGGFCHPITGGGIANAVYTGAMAGEAIL 291

Query: 302 KQPEKLNTAYWRATRKLRLKLFG 324
           +              +  ++LFG
Sbjct: 292 EGD-------LEDYSEESMELFG 307


>UniRef50_UPI0001C421FD hypothetical protein BpOF4_18960 n=1 Tax=Bacillus pseudofirmus OF4
           RepID=UPI0001C421FD
          Length = 438

 Score =  160 bits (404), Expect = 8e-38,   Method: Composition-based stats.
 Identities = 81/365 (22%), Positives = 138/365 (37%), Gaps = 53/365 (14%)

Query: 5   DVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           +V I G G AG  LA KLA K Q+     + Q G     K  G LL P     F    ++
Sbjct: 8   EVFIAGGGVAGLTLALKLA-KHQIDVTVVEKQKGMGNVYK--GELLQPKTLSIFEELEIS 64

Query: 65  LPVDVIANP-QIFSVKTVDVAA----SLTRNYQRSYININRHAF---DLWMKSLIPASVE 116
             ++   NP Q    K VD        +  +Y R  I  N  A    +   + L+  +  
Sbjct: 65  TQINKEINPLQKIVTKEVDEKNRQLLEVVMDYSRLPIENNTAAMIPHNTLKEILLNEASR 124

Query: 117 VYHDSLCR--KIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKY 174
             H  L +     R++    V+ + +G E  I A  ++GA+G  S VR+ +  D  +++ 
Sbjct: 125 YPHFHLLQPAAFLRKEGTNEVVIKREGLESVIEANIIIGAEGRGSKVRKSV--DIPLKQS 182

Query: 175 VAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTL---- 230
               Q+     P P    + D  +            +  F G +P+ DG+ R   L    
Sbjct: 183 TYTHQFLTVTFPSP--PSLVDGEMI---------GNHERFLGLFPLPDGEVRSVLLIRGD 231

Query: 231 ------KEKMSAF----------QFQFGKTVKSEK-CTVLFPSRWQDFVCGKDNAFLIGE 273
                 K+ + AF             +   +KS K   ++ P R       + N  +IG+
Sbjct: 232 EYKQMKKQGLEAFYEAYIQLKPELEGYVNQIKSWKDIQLMVPIRHTVTHYTEGNVVIIGD 291

Query: 274 AAGFISASSLEGISYALDSTDILRSVL-----LKQPEKLNTAYW-RATRKLRLKLFGKIV 327
           AA  +   + EG++ A+    +L  ++     +++P       W    R  R++    + 
Sbjct: 292 AAHSVHPMAGEGMNLAIQDAYVLGDLISWMYEVRRPSDYELLKWFEDVRGERVEYLSWLS 351

Query: 328 KSRCL 332
               L
Sbjct: 352 HQSAL 356


>UniRef50_B1L612 Geranylgeranyl reductase n=1 Tax=Candidatus Korarchaeum cryptofilum
           OPF8 RepID=B1L612_KORCO
          Length = 368

 Score =  159 bits (402), Expect = 1e-37,   Method: Composition-based stats.
 Identities = 64/335 (19%), Positives = 114/335 (34%), Gaps = 23/335 (6%)

Query: 4   FDVAIIGLGPAGSALARKLAGK-MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +D  +IG GP+GS  A  LA K  + + LD K         K CGG +   A       G
Sbjct: 2   WDAIVIGAGPSGSVTAYLLAKKGYKTLILDMKD----FPRYKSCGGGVTWRAYNLLRELG 57

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSL 122
           + L     A  +   ++       +  + + +   ++R   D  +     A    +    
Sbjct: 58  IKLRSP-EAYHKEVVIRGFGEEIKVRSDEEFAVATLDRRKLDKELLDEAIAQGAEFRKEK 116

Query: 123 CRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFA 182
              +  ++D+  VI          ++RY++GADGA S+        +  R    I     
Sbjct: 117 VSGVISKEDRVEVI------GSGFSSRYVIGADGAYSITAISSGIRNCWRNDDIIFAIEG 170

Query: 183 EKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFG 242
                   + I D S  + Y W   +      G        +      +E    ++ +  
Sbjct: 171 RAPLYDELTFIVDAS-PSGYGWIFPRGEDSNAGVGGISSKSREVIKAFEEFSKRYKVEKV 229

Query: 243 KTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLK 302
                     + P+   D    K    L+G+AAG     + EG+ YA  S       L  
Sbjct: 230 GNW-------IIPTGGHDKQIAKGRVLLVGDAAGLADPLTGEGLYYAFKSALECSKSL-- 280

Query: 303 QPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPAL 337
           + E    +Y      + ++      K+R +  P +
Sbjct: 281 ESEDPALSYSENMGNV-MEELRLKRKARNIIVPRM 314


>UniRef50_C3NB54 FAD dependent oxidoreductase n=12 Tax=Sulfolobaceae
           RepID=C3NB54_SULIY
          Length = 395

 Score =  158 bits (399), Expect = 3e-37,   Method: Composition-based stats.
 Identities = 66/328 (20%), Positives = 122/328 (37%), Gaps = 34/328 (10%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            FD+ ++G GPAGS+ A   A    +V+ L++    G E  SK   G +      S + D
Sbjct: 2   KFDIVVVGAGPAGSSAAITAARGGAKVLLLER----GPEPGSKNVSGAMIRLEDFSSVYD 57

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIP-ASVEVYHD 120
             ++P++         + +      ++ N + +   + R   D WM      A   +   
Sbjct: 58  IASIPIERKVKNVDLILLSNSNRTRISVNVESNLATVARLKLDKWMAQQAEKAGALLITK 117

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMV------RRHLYPDHQIRKY 174
           +    + RE +++ V    +     + A  +V A+G N++V      R  L PDH ++  
Sbjct: 118 TTVLGVEREGNEYKV----ETDRGEVRADRVVLAEGVNALVSMKANIRPDLTPDHAVQTV 173

Query: 175 VAI--------QQWFAEKHPVPFYSCIFDNSITNCYSWS--ISKDGYFIFGGAYPMKDGQ 224
             +         + F  K      S          Y+    + KD   I G   PMK   
Sbjct: 174 KEVYSLNKDEVNKRFGFKADDEGVSWRILGIDPVPYAGFLYVYKDAVAI-GAGIPMKILI 232

Query: 225 TR-------FTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGF 277
            R          +KE++   +   G +++     V+    +  +       +L G+A G 
Sbjct: 233 KRKITPYTVLDEVKERLGFNELVKGASLREYSAKVIPEYGFPSWKACSGKIYLAGDAIGL 292

Query: 278 ISASSLEGISYALDSTDILRSVLLKQPE 305
           +   +  GI  A+ S  +     L+  E
Sbjct: 293 VDPLTFNGIGPAVASGVVAGKAALESYE 320


>UniRef50_C4XQT1 Geranylgeranyl reductase n=2 Tax=Desulfovibrio RepID=C4XQT1_DESMR
          Length = 391

 Score =  157 bits (396), Expect = 6e-37,   Method: Composition-based stats.
 Identities = 68/311 (21%), Positives = 102/311 (32%), Gaps = 34/311 (10%)

Query: 5   DVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           DV I+G GPAGS  A  LA +   V+ LDK          K C GLL   A     R   
Sbjct: 6   DVVIVGAGPAGSTAAHVLASRGASVLVLDK----AEFPRDKLCAGLLTWKAVDVLERVFG 61

Query: 64  TLPVDVIAN------PQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEV 117
             P  ++A+      P  + ++  D   +    +   +    R  FD  +      +   
Sbjct: 62  DAPEGLLASGVFNAAPAGYCIRFRDHIIAQGEMF-YPFHLTKRRVFDKHLADRAVKAGAD 120

Query: 118 YHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYV-- 175
               L   + R D     +  ADG E     RY++G DG  S+VRR    D    K    
Sbjct: 121 VR--LGLAVSRVDPATGTVTTADGRE--FRGRYVLGCDGVASVVRRACPFDGANWKAGMG 176

Query: 176 -AIQQWFAEKHPV----------PFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQ 224
            A++ +     P             +  ++   +   Y W          G         
Sbjct: 177 GALEFYIDRDDPRLAAPAHADLRAEHPTVYAGFLRAGYGWVFPHADRLAIGIG---GHSA 233

Query: 225 TRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFV--CGKDNAFLIGEAAGFISASS 282
                 + K   F    G   +           + +++         L G+AAG +    
Sbjct: 234 RHGREFRAKFREFVSFLGLPPELADAAKGHGLPYGNYIEKPWHGRVMLAGDAAGLVETLF 293

Query: 283 LEGISYALDST 293
            EGI YAL S 
Sbjct: 294 GEGIYYALRSG 304


>UniRef50_D2RHK2 Geranylgeranyl reductase n=2 Tax=Archaeoglobaceae
           RepID=D2RHK2_ARCPR
          Length = 386

 Score =  156 bits (393), Expect = 2e-36,   Method: Composition-based stats.
 Identities = 60/326 (18%), Positives = 106/326 (32%), Gaps = 18/326 (5%)

Query: 16  SALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQ 74
           S  A+  A   + V+ ++K+ + G       C   ++ DA   F+          +   +
Sbjct: 14  SIAAKTCAENGLNVLLVEKRQEIGVPVR---CAEGISRDALERFVEPKKFFISREVVGAK 70

Query: 75  IFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLI-PASVEVYHDSLCRKIWREDDKW 133
           IF+    ++  S  +        + R  FD ++ +L   A  EV   +      R+D   
Sbjct: 71  IFAPDGTEITLSEEKAGNEVGYVLERKVFDRYLATLASQAGAEVLVKTTAYDFERKDGIV 130

Query: 134 HVIFRADGWEQHITARYLVGADGANSMVRRHLY-----PDHQIRKYVAIQQWFAEKHPVP 188
            V  R  G E  +  + ++GADG  S V +            I   V       +  P  
Sbjct: 131 KVKLRRMGEEWEVETKLVIGADGVESRVAKFFGIDTTLKPDGIESCVQYLMTNIDFDPDY 190

Query: 189 FYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKTVKSE 248
            Y  +  +     Y W   K      G        +       +     +F  G+ V+  
Sbjct: 191 CYFWLGKSIAPGGYIWLFPKRVGANVGIGVMPSIAKKTPKEYLDDFVQKKFPDGRIVELV 250

Query: 249 KCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQ----- 303
              V  P   +      DN  L+G+AA      +  GI+ A+ +      V  +      
Sbjct: 251 AGAV--PVCGEIKTAVADNVMLVGDAARHADPITGGGIANAMKAGYYAGKVAAEAVKKND 308

Query: 304 -PEKLNTAYWRATRKLRLKLFGKIVK 328
              K    Y +  ++   K   K  K
Sbjct: 309 FSAKFLKRYDKLWKEDFGKELAKKRK 334


>UniRef50_UPI000050FC1D geranylgeranyl reductase n=1 Tax=Brevibacterium linens BL2
           RepID=UPI000050FC1D
          Length = 433

 Score =  155 bits (392), Expect = 2e-36,   Method: Composition-based stats.
 Identities = 67/365 (18%), Positives = 124/365 (33%), Gaps = 47/365 (12%)

Query: 1   MEHF--DVAIIGLGPAGSAL-ARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRS 57
           M  F  +V ++G GPAGSA+ A       +VI L+K          K CG  L P A + 
Sbjct: 1   MNEFSAEVIVVGAGPAGSAIGAYLAQAGHEVIILEKSG----FPRDKICGDALTPRAVKE 56

Query: 58  FIRDGLTLPVDVIANP-----QIFSVKTVDVAASLTRNYQRSYININRHAFDL-WMKSLI 111
               G+  P     +       I     +++            +   R   D  + +   
Sbjct: 57  VGYLGMATPESEGWHKNRGLRLIGGGHRLEIDWPDIDGTPNFGLTKPRMGMDEAFARHAQ 116

Query: 112 PASVEVYHDSLCRKIWREDDKW--HVIF-------RADGWEQHITARYLVGADGANSMVR 162
            +   ++           +D W   V         R  G E H +A  ++ ADG +S + 
Sbjct: 117 RSGARLFEQVKAMSPDIGEDGWIQGVHASGTDHRGRRVGPEAHFSAPIVIAADGVSSRLA 176

Query: 163 RHLYPDHQIRK--YVAIQQWFAEKHPVPFY--SCIF--------DNSITNCYSWSIS-KD 209
             +  + +  +   VA++ + +       Y  S +         ++ +   Y W     D
Sbjct: 177 VAMGLEKRDDRPMGVAVRAYHSSPRHADDYIESWVEMRSRNSAGESEVLPGYGWLFPLGD 236

Query: 210 GYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVL-------FPSRWQDFV 262
           G    G        Q      +  M  +    G     ++ T L        P  +    
Sbjct: 237 GTINIGAGLLDSSPQFGSVDFRTMMGQWIADMGHEWGIDETTSLGPIKSAALPMAFNRTP 296

Query: 263 CGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKL 322
                  L+G++ G ++  + EGI YAL+S  +   V+        + Y +   + +L+ 
Sbjct: 297 HFHKGLLLVGDSGGMVNPFNGEGIDYALESARLAAEVIST-----YSRYPKHVMREKLQE 351

Query: 323 FGKIV 327
           +  +V
Sbjct: 352 YPALV 356


>UniRef50_B4U8N3 Geranylgeranyl reductase n=1 Tax=Hydrogenobaculum sp. Y04AAS1
           RepID=B4U8N3_HYDS0
          Length = 348

 Score =  154 bits (388), Expect = 6e-36,   Method: Composition-based stats.
 Identities = 68/306 (22%), Positives = 104/306 (33%), Gaps = 22/306 (7%)

Query: 5   DVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDA-QRSFIRDG 62
           DV IIG G AGS+ A +LA K   VI +D +   G       C   +     Q+ F    
Sbjct: 8   DVLIIGGGLAGSSAAHQLAKKGVDVIIVDSRKTIG---VPVQCAEFIPKQLMQKKFEDYF 64

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFD-LWMKSLIPASVEVYHDS 121
               V  I N          V            + ++R  FD    +  I +    +  +
Sbjct: 65  KNSVVQEIENMLTIEPDNKKV------YSGSKGVMVDRKVFDANIFQEAIKSGARAFLKT 118

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWF 181
           +    +   DK   I +A     ++   Y+VGADG  S V   ++        V  Q+  
Sbjct: 119 IFIGFY---DKNTAILKAKDDVYYVEFDYIVGADGPRSSVMEKVFSKKH-ELAVCAQRRC 174

Query: 182 AEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYP---MKDGQTRFTTLKEKMSAFQ 238
             K P+     +F   I   Y W   K+ Y   G         D +       +   +  
Sbjct: 175 KLKEPLKDIVIVFREYIKGGYGWIFPKNNYANVGIGIDTAFKDDPKYVLELFIKDAVSMG 234

Query: 239 FQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRS 298
           F      +S       P    D      N  L G+A GF    +  GI  A+ S ++L  
Sbjct: 235 FIENNCDESSGGF--LPLDGIDT-LVSSNVALCGDAGGFCHPITGGGIPQAVVSGNMLAQ 291

Query: 299 VLLKQP 304
            +L+  
Sbjct: 292 YILEND 297


>UniRef50_Q6L1J9 Geranylgeranyl hydrogenase n=3 Tax=Thermoplasmatales
           RepID=Q6L1J9_PICTO
          Length = 379

 Score =  154 bits (388), Expect = 6e-36,   Method: Composition-based stats.
 Identities = 63/329 (19%), Positives = 107/329 (32%), Gaps = 29/329 (8%)

Query: 5   DVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           DV I+G GPAGS  A  L+ K   V+ L++  + G       C GL++            
Sbjct: 3   DVIIVGAGPAGSYAAYLLSKKGFDVLQLEEHREIGK---PVECTGLVSKRVFSMVRSRS- 58

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKS-LIPASVEVYHDSL 122
                 + N    +         +  +     I + R  FD  + +  I    ++  ++ 
Sbjct: 59  ------MINKVHGANVYFPNNKYIHVSKNEETIVMYRDQFDKDVAAMAIENGTDLRINAR 112

Query: 123 CRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQ--QW 180
                  DD   V FR +G  Q    + ++GADG NS VRR L  +   R     Q    
Sbjct: 113 AIDASVNDDFASVKFRENGKIQEEKTKIIIGADGVNSTVRRLLSNERPSRIISTYQVDSS 172

Query: 181 FAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ 240
           +           +  +S    + W++        G           F  + +        
Sbjct: 173 YKMDDQDDVNVYLGSSSSRGFFGWAVPSGDITRIGVGADHDTAIKYFKNINKNF------ 226

Query: 241 FGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTD---ILR 297
                         P R+     GK    L+G+AAG +   S  GI   + S     I  
Sbjct: 227 --NDKILGINGSPIPIRYLKKTYGK-RYMLVGDAAGIVKPLSGGGIYTGMISGKNAAIAA 283

Query: 298 SVLLKQPEKLNTA---YWRATRKLRLKLF 323
             ++ + +    +   Y +  R    +  
Sbjct: 284 ESIIDREDFSEKSMSLYQKLWRSEIGREL 312


>UniRef50_A3JWR6 Geranylgeranyl reductase n=1 Tax=Rhodobacterales bacterium HTCC2150
           RepID=A3JWR6_9RHOB
          Length = 394

 Score =  152 bits (385), Expect = 1e-35,   Method: Composition-based stats.
 Identities = 58/341 (17%), Positives = 128/341 (37%), Gaps = 26/341 (7%)

Query: 25  KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG-LTLPVDVIANPQIFSVKTVDV 83
              V  +DK     +    K CGGL    ++++  R   + +  ++         +  D 
Sbjct: 32  GFSVALVDK----ASFPRDKLCGGLFTGRSRQNMTRIFNVDVYNELFLECSKMRFRAGDR 87

Query: 84  AASLTRNYQRSYININRHAFDLWMKS-LIPASVEVYHDSLCRKIWREDDKWHVIFRADGW 142
             S   +    ++ + R  FD ++    +   V  +  S   ++ + ++   +    DG 
Sbjct: 88  IISEVLDAPIMWLTMRR-NFDEFLFQTALGMGVNNFTGSAALEVNQNENCLQL---KDG- 142

Query: 143 EQHITARYLVGADGANSMVRRHLY----PDHQIRKYVAIQQWFAEKHPVPFYSCIFDNSI 198
              ++ + L+G DG NS V + L+       +I   + ++     +        +  ++ 
Sbjct: 143 -SSLSYKVLIGCDGVNSFVAKSLFGSSFDPTKIGFGLEVEVPIEAEKSPEQTVEVDFSAA 201

Query: 199 TNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRW 258
              Y WS  K      G    +         +K++++ F  ++  +   +      P   
Sbjct: 202 DWGYGWSFPKHKSTTIG----LGGINVENPKMKQRLAEFLTRYPNSTDLKVKGQYLPFGD 257

Query: 259 QDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILR-----SVLLKQPEKLNTAYWR 313
                GK N  L G+AAG +   + EGI+ A+ S ++       ++    P+K    Y +
Sbjct: 258 FRKSPGKANILLAGDAAGLVDPVTGEGIALAMHSGELAALAASDAIKSNAPQKALRRYKK 317

Query: 314 ATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAHIPQLKD 354
           A R     L  +    R +  P   + + ++ +A+   L++
Sbjct: 318 ALRPTHQSL-RQAKLWRLMMFPKPMRSVFQNALANGSSLQN 357


>UniRef50_B4WHJ4 Putative uncharacterized protein n=1 Tax=Synechococcus sp. PCC 7335
           RepID=B4WHJ4_9SYNE
          Length = 398

 Score =  152 bits (385), Expect = 1e-35,   Method: Composition-based stats.
 Identities = 65/357 (18%), Positives = 123/357 (34%), Gaps = 30/357 (8%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           M  +D  I+G GPAG++ A  L+ K   + L +K         KPCGG ++P   + F  
Sbjct: 1   MPLYDCIIVGAGPAGASAAYHLSRKGHQVLLIEKAAL---PRYKPCGGGVSPQVAQWFDF 57

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPA-SVEVYH 119
           D       VI+     +  T  +  ++  + +     + R+ FD ++         ++  
Sbjct: 58  DF----EPVISQKVTRARYTWHLGEAIEVDLKAPIWMVRRNEFDHYLVQQAEKRGTKLLD 113

Query: 120 DSLCRKIWREDDKWHVIFRAD-----------------GWEQHITARYLVGADGANSMVR 162
            +    +           R D                    +    +YL+ ADG    + 
Sbjct: 114 KTKVVAVEFVSGGQTDTTRDDANRTDGGDQVDRWKVMTSRGETFEGQYLIAADGGRGPMA 173

Query: 163 RHLYPDHQIRKYV-AIQQWFAEKHPVPFYSCIFDNSITNCYSWSISK-DGYFIFGGAYPM 220
           + L    +      AI+     +             + N Y W+  K DGY I  G +  
Sbjct: 174 KWLGFGDRKASIAGAIEIEPKGEVENSHVVHFEFGLLKNGYVWNFPKRDGYSIGSGVF-- 231

Query: 221 KDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQ-DFVCGKDNAFLIGEAAGFIS 279
           +  + +   L   M+ +   FG   ++E         W+ +      NA L GEAA  + 
Sbjct: 232 RTDRRKGKDLVAPMAEYASAFGVDGEAEPKFGHPVYIWKGNQRLHTQNAVLAGEAACVVD 291

Query: 280 ASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPA 336
             + EGI  ++ +       +        +A    T  +  ++  ++  +  L    
Sbjct: 292 PLTAEGIRPSIFTGIKAAEAVSDAIAGNPSALAEYTDIIAEEIGREMKLATKLAKAF 348


>UniRef50_O27753 Digeranylgeranylglycerophospholipid reductase 2 n=1
           Tax=Methanothermobacter thermautotrophicus str. Delta H
           RepID=GGR2_METTH
          Length = 385

 Score =  152 bits (384), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 73/345 (21%), Positives = 116/345 (33%), Gaps = 27/345 (7%)

Query: 3   HFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            +DV +IG   AGS  A   A   + V+ L++  + GT      C G ++    +S    
Sbjct: 2   KYDVVVIGGRVAGSTAAYHAARLGLSVLLLERNPEIGT---PVQCAGGVSDSFFKS--TG 56

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVYHD 120
              LP       +  +V     A  +T N       + R + D ++      A  +V   
Sbjct: 57  LKPLPEFTCTRIRAAAVNGPLGARIVTENPVVRGYILERKSLDKYLALRAAEAGADVLTM 116

Query: 121 SLCRK-IWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRK---YVA 176
           S+    I+RE     V+FR     Q +    ++ ADG  S + R    +   R       
Sbjct: 117 SIAGDLIFREGSVSGVVFRGPDGVQEVECGMVIAADGVQSSIARKAGLETGFRPADLCSC 176

Query: 177 IQQWFAEKHPVPFYSCIFDNS--ITNCYSWSISK-DGYFIFGGAYPMKDGQTR--FTTLK 231
           +Q   A     P     +  S    + Y W   K +G    G     K    R   + L 
Sbjct: 177 VQYEVAGVDVDPETMEFYFGSRFAPSGYLWVFPKGEGRANVGLGIRRKSCSERGPLSYLN 236

Query: 232 EKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALD 291
             M    F+     + E      P          D   ++G+AAG +   +  GI  A +
Sbjct: 237 RFMEERGFK-----RIEFNAGAVPVCGPIERTFTDGLLVVGDAAGQVDPLTGGGIHLAAE 291

Query: 292 STDILRSVLLKQPEK------LNTAYWRATRKLRLKLFGKIVKSR 330
              I   V  +  E         + Y    RK   K   + +K R
Sbjct: 292 CAKIAGEVAAEAIESGRVDGRFLSRYEMRWRKKIGKNLERSLKFR 336


>UniRef50_Q2JG94 Putative uncharacterized protein n=1 Tax=Frankia sp. CcI3
           RepID=Q2JG94_FRASC
          Length = 409

 Score =  152 bits (384), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 70/310 (22%), Positives = 105/310 (33%), Gaps = 27/310 (8%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGK---MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSF 58
             +DV I+G GPAGS  A  L  +   ++V+  DK          K CG  L   A  + 
Sbjct: 4   GSYDVVIVGAGPAGSVAAFALKRRNPRLRVLLTDK----AVFPRDKACGDGLGAGAVAAL 59

Query: 59  IRDGLTLPVDVIANPQIFSVKTVDVA-----ASLTRNYQRSYININRHAFDLWMKSLIPA 113
            R GL   V    +P    V   D                S   + R   D  + +    
Sbjct: 60  RRLGLLGVVHDAISPLSVRVSGPDGTEATAVGPTVAGRDLSGYVLPREILDARLVAAARE 119

Query: 114 -SVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIR 172
             VE+   +         +   + F+       + A  ++GADGA S VRR L    Q  
Sbjct: 120 VGVEMREGTSYHSSELTGNSRVITFKTGSRSNSVEAALMIGADGAYSRVRRDLGVGRQDD 179

Query: 173 KY--VAIQQWFAEKHP------VPFYSCIFDNSITNCYSWSIS-KDGYFIFGGAYP---M 220
           ++  +A++ +     P      V      F + +   Y W     D     G   P   M
Sbjct: 180 RFSSIAMRSYAKFSDPRRAPQEVMPLRLDFSDKVLPGYGWVFPVSDDVVNLGVGLPVSTM 239

Query: 221 KDGQTRFTTLKEKMSAFQFQFGKTVKS--EKCTVLFPSRWQDFVCGKDNAFLIGEAAGFI 278
           ++       L           G  V+   +  +   P   +        A LIG+AA  I
Sbjct: 240 REKSLNPHNLLSAYVEDLRARGFIVEEPNKLLSHYLPHAGKLAPMAHPRAALIGDAAASI 299

Query: 279 SASSLEGISY 288
           +  S EGI Y
Sbjct: 300 NPLSGEGIVY 309


>UniRef50_D1CDE0 Geranylgeranyl reductase n=1 Tax=Thermobaculum terrenum ATCC
           BAA-798 RepID=D1CDE0_THET1
          Length = 398

 Score =  152 bits (383), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 67/364 (18%), Positives = 128/364 (35%), Gaps = 29/364 (7%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           +E  +V I+G GPAGS++A  LA     V+ LDK          KPC   ++P       
Sbjct: 2   IEEREVVIVGGGPAGSSVANVLASLGHDVLLLDKS----RFPRPKPCSEYMSPGILPLLS 57

Query: 60  RDGLTLPVD---VIANPQIFSVKTVDVAASLTRNYQRSYI--NINRHAFDLWMKS-LIPA 113
             G+   +    ++   +I +     +       +   Y    + RH FD  +       
Sbjct: 58  NLGIDADLSGMHMLKGMRIHTPAGSQITIEYVDEHNGRYYAPTMERHVFDKMLLDHAAHK 117

Query: 114 SVEVYHDSLCRKIWREDDKWHVIFR-ADGWEQHITARYLVGADGANSMVRRHLYPDHQI- 171
            VEV + +    +  +D+   +  +  D  +  I  + ++GADG  S+V R+L   + + 
Sbjct: 118 GVEVRYQAKVMSVVSQDNYSILRVQLPDRAQMDIRTKLVIGADGLRSVVARNLSRRYPLI 177

Query: 172 -RKYVAIQQWFAEKHPVPFYSCIFDNSITNCY-SWSISKDGYFIFGGAYPMKDG------ 223
             K + +            Y  ++ +     Y   + +       G    ++        
Sbjct: 178 WPKRMGLVTHINLPGIDADYGDMYVH--PWGYCGVAATGKSSASVGIVLDLRRMALTRGR 235

Query: 224 QTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSL 283
           +  F    +       Q       ++   + P           N  L+G+AAGF    + 
Sbjct: 236 EAIFEDSLKLFPKAHKQICGAASFDRIMGISPIGHGVKEVHGRNWALVGDAAGFFDPFTG 295

Query: 284 EGISYALDSTDILRSVLL------KQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPAL 337
           EGI  A+    +L  V+       +  E L        R  R K     +    ++ P +
Sbjct: 296 EGIYKAVRGGILLGEVVSPYLKVGRIKEGLERYATERARVFRRKSLLVSLIQIFISYPYM 355

Query: 338 RKWI 341
            +++
Sbjct: 356 LEYV 359


>UniRef50_Q2NFZ1 Digeranylgeranylglycerophospholipid reductase 1 n=4
           Tax=Methanobacteriaceae RepID=GGR1_METST
          Length = 403

 Score =  151 bits (381), Expect = 4e-35,   Method: Composition-based stats.
 Identities = 57/337 (16%), Positives = 101/337 (29%), Gaps = 20/337 (5%)

Query: 1   MEHFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSF- 58
           M   DV +IG GPAGS  A+  A G   V+ +DKK + GT    K C   +  +  +   
Sbjct: 1   MLKTDVVVIGAGPAGSMAAKHAALGGANVVLIDKKSEIGT---PKRCAEGVYDEGFKWLN 57

Query: 59  -IRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMK-SLIPASVE 116
              D   +   +                  + +       + R  FD  M      A  +
Sbjct: 58  IEPDERWIAQRIYGATLHSPDGN--SFTVTSEDVPVQGFILERKVFDKHMAMDAARAGAK 115

Query: 117 VYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRK--- 173
           +   +L   I R ++ + +   +      + A+  + ADG  S++ + L  +    +   
Sbjct: 116 IMIKTLVTDIKRNENGFILSCDSIEGTIEVEAKIAICADGPESIMAKKLGINSTTPQNMM 175

Query: 174 YVAIQQWFAEKHPVPFYSCIFDNSITN--CYSWSISKDGYFIFGGAYPMKDGQTRFTTLK 231
             A  +     +        +         Y+W   K       G     +         
Sbjct: 176 SCAQFEMCNVDYNDDEKIEFYLGQDVALKGYAWIFPKGNGVANVGLGVTGNTDKTAYEYI 235

Query: 232 EKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALD 291
                           E      P          DN  + G+AAG ++     GI   + 
Sbjct: 236 MDFIEKCPATKNAQPIEMNIGGDPINGLIEKIYDDNLLICGDAAGQVNPIEGGGIIEGML 295

Query: 292 STDILRSVLLKQPEKLNTA------YWRATRKLRLKL 322
                  V  K  ++ N +      Y+    +L   L
Sbjct: 296 GGMAAGDVAAKAIKEENYSKERLHEYYEKYSELSFNL 332


>UniRef50_D1UBF5 Geranylgeranyl reductase n=1 Tax=Desulfovibrio aespoeensis Aspo-2
           RepID=D1UBF5_9DELT
          Length = 396

 Score =  151 bits (381), Expect = 4e-35,   Method: Composition-based stats.
 Identities = 73/351 (20%), Positives = 119/351 (33%), Gaps = 22/351 (6%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
           +  DV I G GPAG+     LA +   + +  K         K CGGLL   + R     
Sbjct: 3   KRHDVIICGCGPAGATAGLALARRGHSVLMLDKA---RFPRPKLCGGLLTWKSVRLLETV 59

Query: 62  G-----LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFD-LWMKSLIPASV 115
                       VI +           +   +      +  I+R   D   +     A  
Sbjct: 60  FHESVPGLTEAGVITHVSDRYTIRTPASLLTSGAMPYPFHFIDRSRLDARLLDHAARAGA 119

Query: 116 EVYHDSLCRKIWREDDKWHVIFR-ADGWEQHITARYLVGADGANSMVRRHLYPDHQIRK- 173
           +V   +                  ADG    + A +L+GADGANS+VR       + R  
Sbjct: 120 KVMLGARVTACDPGGGSTPARLTLADGT--VLEADHLIGADGANSVVRNSFLGHDRDRFN 177

Query: 174 ---YVAIQQWFAEKHPVPFYSC--IFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFT 228
                AI+             C  ++   I   Y W        + G    ++ G+ +F+
Sbjct: 178 QFMAPAIEVTLDPAALPEPVECPELYVGFIEAGYGWVFPGQDRVLVGLCG-LRRGKVKFS 236

Query: 229 TLKEKMSAFQFQFGKTVKSEKC-TVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGIS 287
            L      F     + V   +   + + +  ++ VCG  +A L+G+A GF+     EGI 
Sbjct: 237 NLFRDFLDFLKIDSRAVPPLRGHPLPYGNALENPVCG--HAMLVGDAGGFVEPLFGEGIF 294

Query: 288 YALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALR 338
           YA+ +       +    E         T +LR  +  ++  S  L     R
Sbjct: 295 YAMCTGLYAGEAVASALEDGQAPGPLYTARLRRDISPELRGSDRLRWLLFR 345


>UniRef50_Q3A4T4 Dehydrogenase, flavoprotein containing n=1 Tax=Pelobacter
           carbinolicus DSM 2380 RepID=Q3A4T4_PELCD
          Length = 384

 Score =  151 bits (380), Expect = 5e-35,   Method: Composition-based stats.
 Identities = 81/365 (22%), Positives = 124/365 (33%), Gaps = 26/365 (7%)

Query: 4   FDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +DVA++G GPAG+  A  LA   + V  LDK          K CGG L   A        
Sbjct: 6   YDVAVVGGGPAGTMAAIGLAKRGIDVCILDK----AEHPRYKVCGGGLLHRAAERLPISP 61

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVYHDS 121
                +V       +         + R++    + + R   D  + +             
Sbjct: 62  EPF-TEVACRNVELNFGGRQEGFVVRRDFPVVRM-VMRADLDAALWEEAGRCGAHCLSGP 119

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWF 181
               +    D   V+ + D  E  + AR++VGADG NS+V R            A++   
Sbjct: 120 KVCDLETSSD--SVLLKTDRGE--VRARFVVGADGVNSVVARRGGWSPSPLAIAALECEL 175

Query: 182 AEKHPVPFYSCI---FDNSITN-CYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAF 237
           A         C    FD       YSW   K  +   G    ++        L+    A+
Sbjct: 176 AVDDGTYGRFCDAARFDIDHPRRGYSWIFPKKNHLSVGLCSMVR--PVSGKGLRADFHAY 233

Query: 238 QFQFGKTVKS--EKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDI 295
               G   K   E    L P   +          L G+AAG     + EG++ AL+S  +
Sbjct: 234 LKNQGIVPKEPGEIHAALIPVFPRLGQLADKGILLTGDAAGLADPLTAEGLTAALESGRL 293

Query: 296 LRSVLLKQP---EKLNTAYWRATRKLRLKLFGKIVKSRCLTA--PALRKWIMRS-GVAHI 349
               + +     EK+   Y +   +  L       K   L    P LR  I R  G A +
Sbjct: 294 AAGAIAEGEMKREKVQAIYRQKLAEGLLADIEVSRKLAVLLYHHPHLRNLIFRFYGQAFV 353

Query: 350 PQLKD 354
            ++ D
Sbjct: 354 EKMTD 358


>UniRef50_Q0W1J4 Predicted FAD-dependent oxidoreductase n=2 Tax=Euryarchaeota
           RepID=Q0W1J4_UNCMA
          Length = 394

 Score =  150 bits (379), Expect = 6e-35,   Method: Composition-based stats.
 Identities = 65/341 (19%), Positives = 112/341 (32%), Gaps = 19/341 (5%)

Query: 3   HFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            +DV ++G GPAGS  A+  A    + + L++  Q G+      C GL++ +A       
Sbjct: 2   DYDVIVVGAGPAGSMAAKYAALNGAKTLLLEEHGQVGS---PVACTGLISRNALDECELG 58

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVYHD 120
             +     I    + S         L    +     + R   D  M +  + A  E+   
Sbjct: 59  EGSFINKRIRGAFVHSPNN---HNILLDGKRTMAYVVERKIMDREMARRAVNAGAEILIS 115

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW 180
           +    I        V        + ITA  ++GADG  S V R     +      AIQ  
Sbjct: 116 TKAEGITPVPGGISVKVTGPDGTEDITASVVIGADGVKSKVARAAGLGNLPHVCSAIQVE 175

Query: 181 FAEKHPVPFYSCIFDNS--ITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQ 238
              +   P +  +F  S      ++W++   G     G    +        L  +     
Sbjct: 176 ATYEPRNPDFVEMFSGSRYAPKHFAWAVPTSGDCCRVGLISDEHAHEYLQRLLTEHEIVS 235

Query: 239 FQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRS 298
            +    V      V   +  +      DN  ++G+AAG +   S  GI        I   
Sbjct: 236 KKARSAVDLIMGGVPVGTLKRTV---TDNIMIVGDAAGQVKPISYGGIYTGARCARIAGE 292

Query: 299 VLLKQPEKLNTA------YWRATRKLRLKLFGKIVKSRCLT 333
           V  K     + +      Y R  R    +    +++ R + 
Sbjct: 293 VAAKAALAGDASSARLMEYERRWRADIGRELMMMMRFRQMY 333


>UniRef50_A0QR89 Geranylgeranyl reductase n=7 Tax=Mycobacterium RepID=A0QR89_MYCS2
          Length = 395

 Score =  150 bits (378), Expect = 7e-35,   Method: Composition-based stats.
 Identities = 67/374 (17%), Positives = 119/374 (31%), Gaps = 33/374 (8%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           + +D+ I G GP+GSA A + A    +V+ LDK          KPCG  L   A     +
Sbjct: 3   QRYDLVIAGGGPSGSAAAWQAAQTGAKVVVLDK----AEFPRDKPCGDGLTARAVSYLQK 58

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRS------YININRHAFDLWMKSLIPAS 114
            GL    +V    ++  V TV   +    ++ R          ++R   D  +     ++
Sbjct: 59  MGL--ADEVATYHRVNRV-TVFSPSEWELSFPRRPGMPDHGHTVSRTHLDTVLLKHAESA 115

Query: 115 VEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKY 174
                          D    VI       + +    ++ ADGA S ++R L  D +   Y
Sbjct: 116 GAEVRQGAEVAGPEFDANGRVIGVVLKSGEKVYGDAVIAADGAYSPIKRALKIDSEYNGY 175

Query: 175 VAIQQWFAEKHPVP-------FYSCIFDNSITNCYSWSIS-KDGYFIFGGAYPMKDGQTR 226
            AI          P       +   +F       Y W     +G F  G  Y       +
Sbjct: 176 SAIAIRSEMHANRPDSDSLDIYLKLVFQGDQLPGYGWVFPMGNGMFNIGLGYVNSYKNWQ 235

Query: 227 FTTLKEKMSAFQFQFGKTVKSEKCTVL----------FPSRWQDFVCGKDNAFLIGEAAG 276
                + +  F     +  +      L           P  +  +   +      G++ G
Sbjct: 236 SINATQFLGEFLRSLPREWELPPIEELKKNKSVRAWRLPMGFTAWPPWRPGVLFTGDSLG 295

Query: 277 FISASSLEGISYALDSTDILRSVLLKQP-EKLNTAYWRATRKLRLKLFGKIVKSRCLTAP 335
               +S  GIS AL+S        +          +    +++      +  + R +   
Sbjct: 296 AGKPASGAGISKALESGLAAGECAIAALQNGGPDDFTNYAQRMEAAWGREYRRGRYMHKL 355

Query: 336 ALRKWIMRSGVAHI 349
             +  +  +GV  I
Sbjct: 356 IGKPKLAEAGVKLI 369


>UniRef50_D1UBL8 Geranylgeranyl reductase n=1 Tax=Desulfovibrio aespoeensis Aspo-2
           RepID=D1UBL8_9DELT
          Length = 405

 Score =  149 bits (377), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 68/327 (20%), Positives = 117/327 (35%), Gaps = 32/327 (9%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M  +DV ++G GPAG+  A   A   + V+ LD+K         K CG  L+  A     
Sbjct: 1   MSDYDVIVVGAGPAGTCTAIHAARQGLHVLLLDQKK----FPREKTCGDALSSLAIAELN 56

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNY----------QRSYININRHAFDLWMKS 109
             GL     ++  P     K     A  +               + I   R   D  +  
Sbjct: 57  SLGLLP--RLLEIPHTPVQKITYHGADTSSVTVPILKIDDTASEAGIICRRILLDALLME 114

Query: 110 LIPASVEVYHD-SLCRKIWREDD-KWHVI-FRADGWEQHITARYLVGADGANSMVRRHLY 166
           +         D     ++  +    + V   R  G     TA+ +VGADG++S+V R + 
Sbjct: 115 IAAEEEVEVVDWCRITEVLVKGGQAYGVKGERGGGRGVSWTAKVVVGADGSDSLVARQMN 174

Query: 167 -PDHQIRKYVAIQQWFAEKHPV-PFYSCIFDNSITNCYSWSISKDGYFIFGGAY-----P 219
            P +   + +A++ +F +   +       F   +   Y W    +      G        
Sbjct: 175 MPRYPEYRALAVRGYFRQVLGIRGNIEVHFPEEVLPGYVWFHPTETSQTNVGLTIPMDVV 234

Query: 220 MKDGQTRFTTLKEKMSA----FQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAA 275
                     LK  +++     +F F + +   +  VL P          +   L+G+AA
Sbjct: 235 KDTNIKPKQALKRALASPELKERFAFAEQMGEIEAGVL-PVGNPIREIHGNGFILVGDAA 293

Query: 276 GFISASSLEGISYALDSTDILRSVLLK 302
           G ++  S +G + A+ S  I   VL K
Sbjct: 294 GLVNPCSSDGTTNAIISARIAGEVLAK 320


>UniRef50_B4UA54 Geranylgeranyl reductase n=1 Tax=Hydrogenobaculum sp. Y04AAS1
           RepID=B4UA54_HYDS0
          Length = 376

 Score =  149 bits (377), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 64/326 (19%), Positives = 116/326 (35%), Gaps = 21/326 (6%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           ME +DV +IG GPAG+  + +LA    +V+ ++K          K C G ++  +   F 
Sbjct: 1   MERYDVIVIGGGPAGAGASYELADAGAKVLVIEKAK----YPRPKLCAGCISKRSVDLF- 55

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPA-SVEVY 118
                 P   I N     +        + +      + ++R  FD ++ S        + 
Sbjct: 56  ------PAFNIKNSIKGGILGFKGQEFVEKVSDECAVIVDREEFDHFLISKAQEKGAHLL 109

Query: 119 HDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQ 178
            +   + I        VI      +    A Y++GADG +S+ R+ +      RK+    
Sbjct: 110 EEITAKDIELTPTVRKVIT----DKGVFEADYVIGADGYHSITRKSIACKSASRKFFIAM 165

Query: 179 QWFAEKHPVPFY---SCIFD-NSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKM 234
           +    K     +     + D   +   Y W   +  +   G A   K+          K 
Sbjct: 166 EVKVPKDMFKDFKEDEVLIDIGVVKKGYGWYFPQGEFVNIGIATAEKEDLLNIFKAYTKN 225

Query: 235 SAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTD 294
                      + +   + F S+ Q+   G+D  FL G+A   +     EGI YA  S  
Sbjct: 226 HKLFPIDISKYRIKSWFIPFISKAQELRLGRDRVFLTGDAGAIVDPLLGEGIRYAYLSGS 285

Query: 295 ILRSVLLKQPEKLNTAYWRATRKLRL 320
           +    +    +  ++ Y R  +   L
Sbjct: 286 LCARAIKLAKKDAHSLYERFVKNTIL 311


>UniRef50_A1RY40 Geranylgeranyl reductase n=1 Tax=Thermofilum pendens Hrk 5
           RepID=A1RY40_THEPD
          Length = 387

 Score =  149 bits (376), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 71/346 (20%), Positives = 120/346 (34%), Gaps = 19/346 (5%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            +D A++G GPAG   AR LA K  +V  L+K          KPCG  ++    ++   +
Sbjct: 2   QYDAAVVGAGPAGLMFARVLASKGFRVAVLEKNETLAV----KPCGEGISARVLQTAEIN 57

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVYHD 120
                  V    +   V   +    + +        I++  F   M +       ++Y  
Sbjct: 58  RSDTQRFVSHAIKGAVVVAPNGRKVVIKEEGELGYVIDKRNFLRVMGEYAASYGADIYMK 117

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYV----- 175
              +++  ++  W V  R       + AR LVGADG  S   + L  +    + V     
Sbjct: 118 EPVKEVVFKNGHWTVRART----VELEARLLVGADGYLSYTAKALGLEKPGERRVIPTVQ 173

Query: 176 AIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMS 235
            +      + P   Y  + +      Y W   KDG     G          +  L + + 
Sbjct: 174 YVMPNVELEDPDMTYFFLGNEVAPKGYVWIFPKDGRLANVGIGVQGASPKAY--LDKFIK 231

Query: 236 AFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDI 295
                FGK    E                 ++A L+GEAAG +   +  GI  ++    I
Sbjct: 232 NNPSIFGKARILEFRGAAVTIGGMLSEIVSEHAMLVGEAAGQVIPLTGGGIHTSIAGGKI 291

Query: 296 LRSVLLKQPE--KLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRK 339
              V  K      L+       +KL  + +GK ++       A+ K
Sbjct: 292 AAEVASKALAEGDLSKKRLEEYKKLYNEYWGKRIRDSLKGLHAIEK 337


>UniRef50_A2BVI2 NAD binding site n=7 Tax=Prochlorococcus marinus RepID=A2BVI2_PROM5
          Length = 377

 Score =  149 bits (375), Expect = 2e-34,   Method: Composition-based stats.
 Identities = 57/305 (18%), Positives = 110/305 (36%), Gaps = 17/305 (5%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGK-MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M+ FD  IIG G +GS+ A  L+ K   V+ ++K+      G  KPC G +A  + + ++
Sbjct: 1   MKEFDAIIIGGGLSGSSTALNLSKKGYSVLIIEKEAT----GIIKPCAGGMA-SSMKQYL 55

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMK-SLIPASVEVY 118
              +   ++       F  ++ D   +        +  I R   D  +    +   +E+ 
Sbjct: 56  PLDIDQAIESKIRNVEFRWESSDNVNADLSGES-PFWIIRREKLDQLLLDEALKNGIEIL 114

Query: 119 HDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQ 178
             +   +I  ++  W +       +    ++YLV ADG+ S    +     +  K+    
Sbjct: 115 RPAQVEEIISQNKTWRIKCSH---KDIYKSKYLVIADGSQSQWAGYFNLGPRKPKFANTI 171

Query: 179 Q-WFAEKHPVPFYSCIF-DNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEK-MS 235
                    +P  S  F    I   ++W+         G    + +       L  K + 
Sbjct: 172 ALRLKGLGNIPKDSVRFEFGFIKYGFAWAFPLKDSVNIGLGTFINNKLLEDEALNNKVLK 231

Query: 236 AFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDI 295
           +F F+     K  K   ++    +      D    +G+AA        EGI  +L S+  
Sbjct: 232 SFGFEDLSFEKVHKKLRIWNGTHK---LNGDRVVAVGDAASLCDPFLAEGIRPSLISSYF 288

Query: 296 LRSVL 300
               +
Sbjct: 289 AAESI 293


>UniRef50_A6UWL1 Digeranylgeranylglycerophospholipid reductase n=12
           Tax=Methanococcales RepID=GGR_META3
          Length = 391

 Score =  149 bits (375), Expect = 2e-34,   Method: Composition-based stats.
 Identities = 60/344 (17%), Positives = 104/344 (30%), Gaps = 25/344 (7%)

Query: 3   HFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            +DV +IG GP GS  +   +    + + +DK  + GT      C   +           
Sbjct: 8   EYDVIVIGAGPGGSMASYHSSINGAKTLLIDKSQEIGTPVR---CAEAVPY-----LDEF 59

Query: 62  GLTLPVDVIANPQIFSVKTVD-VAASLTRNYQRSYININRHAFDLWMKSL-IPASVEVYH 119
           G+      I +     +         + +  +     + R  FD  +         ++  
Sbjct: 60  GINPDPSFIRSKIDGGILVAPNGKKIIVKGGKTQGYVVERKIFDKHLAVRSANVGTKIAI 119

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRH--LYPDHQIRKYVAI 177
            S    +  + +K+ VI    G    I A+ ++ ADG  S +     +    ++ +  + 
Sbjct: 120 KSRVVGLDYDGEKYTVIVNHLGQIYAIKAKIVIAADGVESSIAEMAGIKCKKKVTEICSC 179

Query: 178 QQW--FAEKHPVPFYSCIFDNSI-TNCYSWSISKDGYFIFGGAY--PMKDGQTRFTTLKE 232
            ++     K         +   I    Y W   K      G       K          E
Sbjct: 180 AEYEMTNVKLLDKNMMEFYFGDICPKGYVWIFPKGETANVGLGIIDSKKKAIDYLNEFLE 239

Query: 233 KMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDS 292
                      T    KC    P          DN  ++G+AAG IS  S  GI  +L  
Sbjct: 240 HPLLEGRLDNATPIEFKCGG-APVGGPIEKTVADNFMVVGDAAGQISPISGGGIYLSLSC 298

Query: 293 TDILRSVLLKQ------PEKLNTAYWRATRKLRLKLFGKIVKSR 330
             I   V  +        E     Y    ++   KL    +K +
Sbjct: 299 GSIAGKVAGEAIKSNNCSEDYLVEYENRWKEKYYKLLMDELKYK 342


>UniRef50_A8M3W4 Geranylgeranyl reductase n=1 Tax=Salinispora arenicola CNS-205
           RepID=A8M3W4_SALAI
          Length = 382

 Score =  148 bits (373), Expect = 3e-34,   Method: Composition-based stats.
 Identities = 64/317 (20%), Positives = 117/317 (36%), Gaps = 32/317 (10%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M  +D+A++G GPAG + A   A      + L++          K CGG L   +  + +
Sbjct: 1   MTVWDLAVVGAGPAGLSAAYVAARAGVDTVVLER----AVHPRYKTCGGGLIGTSL-AVV 55

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYI--NINRHAFDLWMKSLIPASVEV 117
            D + +P    A+   F+        + TR      +   + R  FD  +++   A+   
Sbjct: 56  ADRIEVPAHDRADRVTFTW---SGRRAFTRRSAGGPLVTMVRRDEFDDRLRAAAVAAGAT 112

Query: 118 YHDS-LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDH------- 169
                  R +  E D   +          +TAR ++GADG++ +  RH+   H       
Sbjct: 113 LRQRVAVRSVEPEPDGVRLRL---VDGTTVTARSVIGADGSSGVTARHVGVRHRQVDLGL 169

Query: 170 --QIRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRF 227
             ++    A+Q  +  +  V +        +   Y+W   K+     G       G+   
Sbjct: 170 ELELPVPPALQARWRGRVLVDW------GPLPGSYAWVFPKNDLLTVGVIAARGAGERTR 223

Query: 228 TTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGIS 287
             L+  +        + V       L   R +     +    + G+AAG +   S EGIS
Sbjct: 224 AYLRSFVDRLGLADVEPVHDSG--HLTRCRQEGSPLRRGRVLVAGDAAGLLEPWSREGIS 281

Query: 288 YALDSTDILRSVLLKQP 304
           YAL S ++  + +    
Sbjct: 282 YALRSGELAGAAVAADD 298


>UniRef50_B4CVZ2 Geranylgeranyl reductase n=1 Tax=Chthoniobacter flavus Ellin428
           RepID=B4CVZ2_9BACT
          Length = 357

 Score =  148 bits (373), Expect = 3e-34,   Method: Composition-based stats.
 Identities = 75/350 (21%), Positives = 118/350 (33%), Gaps = 29/350 (8%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            +DVAIIG GPAGS  A   A    + + ++K          K CG  + P       R 
Sbjct: 2   EYDVAIIGAGPAGSTCAAHCAQAGWRTLVIEK----ARFPRDKVCGDCVNPACWPILDRL 57

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTR----NYQRSYININRHAFDLWMKSLIPA-SVE 116
           G+T  +    + ++  V  V       R    +  R  I I R  FD  +         E
Sbjct: 58  GVTDRLHAQPHSRLKEVAFVSPQGRTLRLPLPDSDRGEIAIPRRLFDAVLLDRARELGAE 117

Query: 117 VYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYP-DHQIRKYV 175
           V+ D+    +      W +           +ARYL+ ADG NS V R L       +  +
Sbjct: 118 VHEDAPLTALE---SGWKLQTTR----GSFSARYLIAADGRNSTVARLLGLLPAAAKDRI 170

Query: 176 AIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMS 235
            +Q        +     +           +   +  F       +     R   LK   +
Sbjct: 171 GLQAHLPIPSGMHERVAMHFLPFG-YCGMNDIGNEQFNLC----LVARPERLADLKAWAA 225

Query: 236 AFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDI 295
           A   +F    ++   T+  P          +    IG+AA  +   + EGI YAL S ++
Sbjct: 226 A---RFDIAPETAWRTIT-PLSRAPIGTVHERLLAIGDAARIVEPFTGEGIYYALASGEL 281

Query: 296 LRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSG 345
               LL     L        R  R +L+   +    +  P L   I+   
Sbjct: 282 AARHLL--ANDLPGFAAAHARLYRGRLWVNELARAAVLRPWLATGILEFA 329


>UniRef50_Q12X19 Geranylgeranyl reductase n=1 Tax=Methanococcoides burtonii DSM 6242
           RepID=Q12X19_METBU
          Length = 399

 Score =  147 bits (372), Expect = 4e-34,   Method: Composition-based stats.
 Identities = 58/337 (17%), Positives = 115/337 (34%), Gaps = 18/337 (5%)

Query: 4   FDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +DV ++G GP GS  AR    G  +V+ +++    G+      C GLL+  A        
Sbjct: 3   YDVVVVGAGPTGSTAARYATMGGAKVLIIEEHFSIGS---PVECTGLLSTRAVSE---CD 56

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRS-YININRHAFDLWMKSLI-PASVEVYHD 120
           +    D + N    +         L  + +R+    ++R  FD  + SL      E+   
Sbjct: 57  VRPEDDFVLNSVRGAFVNSPNGTCLPIDGKRTKAYVVSRKIFDRHLVSLAVDTGAELMLK 116

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW 180
                I ++D    +     G    + ++ ++GADG  S V R+       R    +Q  
Sbjct: 117 GRVTGIQQKDGIQLLSVIHMGKMITVRSKVVIGADGVKSNVARYTGLGKVDRILSGVQIE 176

Query: 181 FAEKHPVPFYSCIFDNS-ITNCYSWSISKDGYFI-FGGAYPMKDGQTRFTTLKEKMSAFQ 238
                    +  +F  S     ++W++  +      G A    +       L++ ++  +
Sbjct: 177 AVYSSNDTDFVELFVGSQAPGFFAWTVPVNERISRIGLAVEPGNEHNAINYLRKIVNKNK 236

Query: 239 FQFGKTVKS-EKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGIS----YALDST 293
              G    +     V             D   + G+AAG +  +S  G+      A  + 
Sbjct: 237 HLAGNCTNNMLDLVVGGIPIGPLKRTYSDGILIAGDAAGQVKPTSGGGVYTGAVCAKMAG 296

Query: 294 DILRSVLLKQPEKLN--TAYWRATRKLRLKLFGKIVK 328
            +    + ++    N    Y    +    +     +K
Sbjct: 297 QVAAEAVSEENFSANRLKEYESRWKSALGRELRTGMK 333


>UniRef50_Q31RA2 Geranylgeranyl reductase n=13 Tax=cellular organisms
           RepID=Q31RA2_SYNE7
          Length = 457

 Score =  147 bits (371), Expect = 5e-34,   Method: Composition-based stats.
 Identities = 64/335 (19%), Positives = 122/335 (36%), Gaps = 31/335 (9%)

Query: 6   VAIIGLGPAGSALARKL-AGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           VA++G GPAGS  A  L    ++   +++K         KPCGG +       F      
Sbjct: 47  VAVVGGGPAGSCAAETLVKAGIETYLIERKLDNA-----KPCGGAIPLCMVSEFD-LPAE 100

Query: 65  LPVDVIANPQIFSVKTVDVAASLTRNYQRSYINI-NRHAFDLWMKSLIPASVEVYHDSLC 123
           +    + N ++ S        ++  +    YI +  R   D +++           +   
Sbjct: 101 IIDRRVRNMKMISPSN--REVNINLDNADEYIGMTRREVLDGFLRDRAAKLGTKLINGTL 158

Query: 124 RKIW--REDDKWHVIFRADGWEQHITA-------RYLVGADGANSMVRRHLYPDHQIRKY 174
            ++   + D   +V+  AD     +           ++GADGANS + + +         
Sbjct: 159 FRLELPKGDRDPYVLHYADHSNGSLEGIPSTLEVDVVIGADGANSRIAKAI-DAGDYNYA 217

Query: 175 VAIQQWFAEKHPVPFYS------CIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQ--TR 226
           +A Q+          Y        +  +   + Y+W   K  +   G      + +   +
Sbjct: 218 IAFQERIRLPEDKMHYYENLAEMYVGGDVSPDFYAWVFPKYDHVAVGTGTMHVNQRLIKK 277

Query: 227 FTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGI 286
                   +A + + GK +K E   +    R +  V     A L+G+AAG+++ SS EGI
Sbjct: 278 LQAGIRARAANRLEGGKIIKVEAHPIPEHPRPRRVV---GRAALVGDAAGYVTKSSGEGI 334

Query: 287 SYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLK 321
            +A  S  +    +++           A  K  L+
Sbjct: 335 YFAAKSGRMCAETIVETSNNGARIPTEADLKQYLR 369


>UniRef50_Q2RLB4 Geranylgeranyl reductase n=1 Tax=Moorella thermoacetica ATCC 39073
           RepID=Q2RLB4_MOOTA
          Length = 341

 Score =  147 bits (370), Expect = 6e-34,   Method: Composition-based stats.
 Identities = 66/321 (20%), Positives = 104/321 (32%), Gaps = 19/321 (5%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           M  +D  + G GPAGS  AR +A     + L +K      G+   C   +          
Sbjct: 1   MLKYDAVVAGAGPAGSTAARVVAAAGARVLLIEKR--ARVGYPVQCAEYVPALIASEVDF 58

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKS-LIPASVEVYH 119
              ++ + V      F   TV        +       +NR  FD  +    + A  E++ 
Sbjct: 59  GEKSIALAVGTLVTFFPDGTVT-------STPAPGYILNREVFDASLAEGAVKAGAELWL 111

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQ 179
            +    +    D   +I +A+G  Q + A  ++GADG  S+V R            A+Q 
Sbjct: 112 KATVEDLT---DTSLIIRQANGRRQEVEAGVIIGADGPLSLVARTRGWPRA-TLAAAVQV 167

Query: 180 WFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQF 239
             A   P+      FD      Y+W   K      G      +  T    L   +    +
Sbjct: 168 EMALPEPMQVTRVYFDPLYRGGYAWVFPKGKTANVGVGLVPGEI-TPAAALTHFLRRLGW 226

Query: 240 QFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSV 299
           Q    V+      L P         +    L G+A GF    +  GI  A+ S  +    
Sbjct: 227 QQQNIVRRTGG--LIPVAGPYQEVHRGRVLLCGDAGGFTHPVTGAGILTAILSGRLAGEA 284

Query: 300 LLK--QPEKLNTAYWRATRKL 318
                        Y  + R L
Sbjct: 285 AAAYLGSGAPLATYEESWRDL 305


>UniRef50_A3EQU0 Geranylgeranyl reductase family protein n=2 Tax=Leptospirillum sp.
           Group II RepID=A3EQU0_9BACT
          Length = 416

 Score =  147 bits (370), Expect = 7e-34,   Method: Composition-based stats.
 Identities = 72/356 (20%), Positives = 125/356 (35%), Gaps = 33/356 (9%)

Query: 5   DVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           D  ++GLGPAG+   R L+   ++V+ LD+          K CGG ++  A     +   
Sbjct: 16  DAIVVGLGPAGATAIRLLSEAGLRVVGLDR----AVFPRPKICGGGVSSRAIAFLPKGWD 71

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIP-ASVEVYHDSL 122
            +P  V     +               Y  +Y   +R   D ++      A  E+     
Sbjct: 72  EIPHTVSTGVHLVFGDH--SPVLWDMGYPIAY-QFDRSDLDWFLLDRARLAGGEIRQGET 128

Query: 123 CRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRK--------- 173
            R + + ++ + +            +R+L+GADG  S V R L    +            
Sbjct: 129 IRSLAKREEIFRLQC---DSGPTYESRFLIGADGVTSSVLRFLAKSKRDDSDGAIPLKNS 185

Query: 174 ----YVAIQQWFAEKHPVPFYSCIFD-NSITNCYSWSISK-DGYFIFGGAYPMKDGQTRF 227
               Y A +   + +        + D +S++  Y WS SK  G    G    +K  +   
Sbjct: 186 SYHMYPAAEVEISTQTSQRLSDVLIDLSSVSGGYGWSFSKSGGKKNVGVVGFVKPLKRPL 245

Query: 228 TTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKD--NAFLIGEAAGFISASSLEG 285
            TL+  +  F  +          +      +  F         FLIG+A   +     EG
Sbjct: 246 ETLRLFLETFPEREIFQDARGSSSAWLIPDYSRFDAHGKIPGLFLIGDAGAMVDPFLGEG 305

Query: 286 ISYALDSTDILRSVLL---KQPEKLNTAYWRATRKLRLKL-FGKIVKSRCLTAPAL 337
           I YAL S     S L+     PEK + +Y +    +  +  +   + S     P +
Sbjct: 306 IYYALLSGARAVSDLILHRTSPEKASRSYAQWAHSIFREFSYAHKLASVVYRFPGI 361


>UniRef50_D2VJZ4 CMF receptor CMFR1 n=1 Tax=Naegleria gruberi RepID=D2VJZ4_NAEGR
          Length = 505

 Score =  147 bits (370), Expect = 7e-34,   Method: Composition-based stats.
 Identities = 59/332 (17%), Positives = 106/332 (31%), Gaps = 39/332 (11%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
             +DV I+G GP+G+  A  LA    +V+ L++K+        K CG             
Sbjct: 77  NEYDVCIVGAGPSGATCAYYLAKFGYKVLVLEQKY----FPREKTCGDGCTAKTLAYLKE 132

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYIN-------------INRHAFDLWM 107
            G+   ++            +     L+                      I R   D  +
Sbjct: 133 MGVLQELEKEGKVASMGSGGIVGPNGLSFIENSGATIEKISGDNNWTPKAIKRIHMDEKV 192

Query: 108 KSLIPA-SVEVYHDSLCRKIWRE---DDKWHVIF----RADGWEQHIT--ARYLVGADGA 157
                    ++       K+ R       W ++     + DG  + +   A  LV ADGA
Sbjct: 193 ARACQKMGADLKEGMDVTKVSRNFVGLKGWSIVANHTPKEDGETKQVKFLASVLVCADGA 252

Query: 158 NSMVRRHLYPDHQIRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDG------Y 211
            S +   L   ++  + ++ + + +           +   +   Y               
Sbjct: 253 PSKLATSLKMVNEEPQGISSRVYVSNHKMETNCIIFYPKPVLPGYCSMFCHSDGDVSLCT 312

Query: 212 FIFGGAYPMKDGQTRFTTL---KEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNA 268
           +I  G  P KD   +       ++ +           +  K   L      +     DN 
Sbjct: 313 YIVPGGKPTKDDLGKLHEYCTTEDPLITKALGPNPQWQQMKAAYLRLGGISNSY--GDNI 370

Query: 269 FLIGEAAGFISASSLEGISYALDSTDILRSVL 300
            +IG+A G I+  + EGI YA+DS  +   VL
Sbjct: 371 LVIGDACGLINPMTGEGIHYAMDSGKMAAEVL 402


>UniRef50_Q6L0M1 Digeranylgeranylglycerophospholipid reductase n=6 Tax=Euryarchaeota
           RepID=GGR_PICTO
          Length = 397

 Score =  146 bits (368), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 56/344 (16%), Positives = 115/344 (33%), Gaps = 28/344 (8%)

Query: 4   FDVAIIGLGPAGSALARKLAGK-MQVIALDKKHQCGTEGFSKPCGGLLAPDAQR--SFIR 60
           +DV +IG GPAGS+ AR  A K ++ + ++K+   G+      CG  ++           
Sbjct: 5   YDVLVIGAGPAGSSAARFAARKGLKTLLIEKRPDIGSPVR---CGEGVSKSWMPEVELKP 61

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKS-LIPASVEVYH 119
           +   +  +V         +   +  +           + R  FD  + +       +V+ 
Sbjct: 62  EDHWISDEVKGARIYGPSEKKPIMLTAENAGNEVGYVVERDKFDKHIAALAASEGADVWV 121

Query: 120 DSLCRKIWREDDKW-HVIFRADGWEQHITARYLVGADGANSMVRRHLYPD----HQIRKY 174
            S    + ++ ++      R +     + A+ ++ ADG  S   R          +    
Sbjct: 122 KSPALSVIKDGNRIVGAKVRHNSEIVDVRAKMVIAADGFESEFGRWAGLKSLILAKNDII 181

Query: 175 VAIQQWFAEKHPVPFYSCIFDNS-ITNCYSWSISKDGY-FIFGGAYPMKDGQTRFTTLKE 232
             ++           Y+  +  S     Y W   K  +    G    +   + RF  +K 
Sbjct: 182 SCVEYRMINVDSDEDYTDFYLGSCAPAGYIWVFPKGKHEANVGIGVTISKMRDRF-DVKN 240

Query: 233 KMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFL-----IGEAAGFISASSLEGIS 287
            + AF         S+  T+   +        +D   L     +G+AA  I   +  GI+
Sbjct: 241 YLDAFIKSH--PGYSKGKTIQLITGGVSVSKVRDKFTLPGLLTVGDAARLIDPITGGGIA 298

Query: 288 YALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRC 331
             + S      V  K  +           +  +  + ++VK + 
Sbjct: 299 NGMISGKYAAEVSKKAIDN------EDYSQEMMNNYERMVKDKF 336


>UniRef50_Q3JCF5 Geranylgeranyl reductase n=2 Tax=Nitrosococcus oceani
           RepID=Q3JCF5_NITOC
          Length = 384

 Score =  146 bits (368), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 66/330 (20%), Positives = 122/330 (36%), Gaps = 28/330 (8%)

Query: 26  MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT--LPVDVIANPQIFSVKTVDV 83
            +V  +++K    T    K CGGLL+  AQ+ F++       P  V    Q  S      
Sbjct: 27  FKVALVERK----TFPREKLCGGLLSARAQKEFMQIFGENKWPAMVERTAQGASFYYQTR 82

Query: 84  AASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLCRKIWREDDKWHVIFRADGWE 143
             +   ++Q  +   +R  FD  + +L   +     + +       D K           
Sbjct: 83  YLNGVHDHQPFFFT-SRIHFDACLAALAREAGAYLLEGIVVTSLEADGKAV----RLNNG 137

Query: 144 QHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEKHPVPFYSC----IFDNSIT 199
           + + A ++VGADG  S +   +      +K +A+         +   +     I+     
Sbjct: 138 KMLKADFVVGADGVRSRIAEAILLHTASKKNLALGLEIEVPLELTTKTVVDPEIYLGVAK 197

Query: 200 NCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVL-FPSRW 258
             Y W   K      G    +    T+   LK   + F  Q   ++ + +C     P   
Sbjct: 198 WGYGWIFPKKETQTVGIGGLL----TKNPDLKSTFNTFLRQHYGSLPNIRCKGYHLPFGS 253

Query: 259 QDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDI-----LRSVLLKQPEKLNTAYWR 313
                G+ N  L+G+AAG +   + EGI++A+ S  +     + +    QPE     Y R
Sbjct: 254 YKRNPGRANILLVGDAAGLVEPVTGEGIAFAMQSGRLAAKAIVAAAGAGQPESALKYYLR 313

Query: 314 ATRKLRLKLFG--KIVKSRCLTAPALRKWI 341
             + + + LF   K+++      P  R ++
Sbjct: 314 EYQSI-VSLFSQAKMMRYLVFPDPMQRLFV 342


>UniRef50_D1YYN0 Geranylgeranyl reductase n=1 Tax=Methanocella paludicola SANAE
           RepID=D1YYN0_METPS
          Length = 389

 Score =  146 bits (368), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 61/343 (17%), Positives = 105/343 (30%), Gaps = 24/343 (6%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGK-MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
            ++DV ++G GPAGS  A   A K + V+ ++K+ + G       C   +       FI 
Sbjct: 3   NNYDVIVVGAGPAGSVAATTAARKGLDVLLIEKRQEIGVPVR---CAEGVIKAGLDEFIE 59

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKS-LIPASVEVYH 119
                P  V A  +   +   D           +   ++R  FD  +      A  EV  
Sbjct: 60  YD---PKWVCAEVRRGRIHAPDGNMLCFSQEDTAGYILDRKIFDRSLAKTAAHAGSEVQV 116

Query: 120 DSLCRKIWREDDKWH-VIFRADGWEQHITARYLVGADGANSMVRRH---LYPDHQIRKYV 175
            +    +  ED     +  +  G E    A+ ++GADG  S + R    L P        
Sbjct: 117 KTQATGLIIEDGCVKGITGKCRGQEFEARAKVIIGADGVESKIGRQAGLLGPLRLKDVES 176

Query: 176 AIQQWFAEKHPVPFYSCIFDNS--ITNCYSWSISKD-GYFIFGGA-YPMKDGQTRFTTLK 231
             +   +     P    ++  +      Y W   K       G A    +          
Sbjct: 177 CAEFLVSGIDIDPDCLELYFGNKLSPGGYLWVFPKGKNEANIGVANLADRLNGAHPIDYL 236

Query: 232 EKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALD 291
           E+  +  F  GK ++     V   +             L G+ A  +      GI  A+ 
Sbjct: 237 ERYVSEHFPDGKIIQVVSGAVPVCNLPGRLSM--SGLLLAGDGARLVDPLLGAGIMNAMI 294

Query: 292 STDILRSVLLKQPEK------LNTAYWRATRKLRLKLFGKIVK 328
           S  +  ++                 Y    R    K   +  +
Sbjct: 295 SGRMAGNIAANAINAGDVSAKALKTYDHEIRSTIGKAIRRNYR 337


>UniRef50_A5D5E0 Dehydrogenases n=1 Tax=Pelotomaculum thermopropionicum SI
           RepID=A5D5E0_PELTS
          Length = 401

 Score =  145 bits (366), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 67/321 (20%), Positives = 106/321 (33%), Gaps = 12/321 (3%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           +DV +IG GPAG   A  +AGK   + + ++H     G    C GL++P   ++      
Sbjct: 3   YDVIVIGGGPAGCKTAGLIAGKGYRVLVAEEH--PRIGTPVQCAGLVSPRTLKA-----A 55

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQRSY-ININRHAFDLWMKSLIP-ASVEVYHDS 121
            +P  VI N             +L    + +    I+R  FD  +      A  E+    
Sbjct: 56  GMPDGVIINEIKGVYVHSPGGETLAVRCKDAAAFVIDRAGFDRKLAERAQSAGAEILTGV 115

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWF 181
                    +K  V  ++   E    AR ++GADGANS V R +                
Sbjct: 116 KAGLGKLLAEKIIVKLKSSRGESSARARLVIGADGANSRVARRINAPRSGEVVRMFAAEV 175

Query: 182 AEKHPVPFYSCIFDNS--ITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQF 239
             K P    + IF         + W I  DG     G       +           A + 
Sbjct: 176 QLKCPEEDMAHIFLGREIAPGWFGWLIPVDGRRARAGIGVCGVDKHPREYFYRLAEARRD 235

Query: 240 QFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSV 299
            F             P      + G D   L+G+AA      S  G+   +   ++   V
Sbjct: 236 IFKDMKVICYTGGAVPIGLPPRIYG-DRILLVGDAACQTKPISGGGLYLGMRGAELCAKV 294

Query: 300 LLKQPEKLNTAYWRATRKLRL 320
             K   + + +  R +   R 
Sbjct: 295 ATKALSREDLSAERLSEYQRR 315


>UniRef50_UPI000038E1B1 geranylgeranyl hydrogenase n=1 Tax=Ferroplasma acidarmanus fer1
           RepID=UPI000038E1B1
          Length = 393

 Score =  145 bits (365), Expect = 3e-33,   Method: Composition-based stats.
 Identities = 59/330 (17%), Positives = 112/330 (33%), Gaps = 28/330 (8%)

Query: 4   FDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +DV + G GP+GS L+  L+    +V+ L++  + G       C GL++    +      
Sbjct: 15  YDVIVSGAGPSGSYLSYLLSRNGYKVLQLEEHREVGK---PVECTGLVSERVFKYVNSRS 71

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKS-LIPASVEVYHDS 121
                  + N    +        S+  +     I + R  FD  + +  I A  +   ++
Sbjct: 72  -------MVNEVHGANVFFPNGKSIHISKGEKTIVMYRDDFDKDVSAMAIGAGADTRINA 124

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQ--Q 179
                   D    V +R +G  ++  A  +VGADGANS +R  L  +   +     Q   
Sbjct: 125 RVLDAKVNDSYGEVKYRENGEIKYARANIIVGADGANSRIRLSLNYERPKKIISTYQVDS 184

Query: 180 WFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQF 239
            F           I   +    + W++        G             T  +       
Sbjct: 185 SFHLDDQDDVNVFIGSENSKGFFGWAVPSGEITRIGVGVDH-------VTAIKYFRNINV 237

Query: 240 QFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSV 299
           +F ++          P  +     G + + L+G+AAG +   S  GI   + S     + 
Sbjct: 238 KFNRSQILGINAGPIPINYLSKTYG-NRSLLLGDAAGIVKPLSGGGIYTGIISAKNAYTA 296

Query: 300 LLKQ------PEKLNTAYWRATRKLRLKLF 323
           + +        E    AY +  ++   +  
Sbjct: 297 IDQSFNRNNFSEDALKAYQKLWKREIGREL 326


>UniRef50_B1L6M6 Geranylgeranyl reductase n=1 Tax=Candidatus Korarchaeum cryptofilum
           OPF8 RepID=B1L6M6_KORCO
          Length = 380

 Score =  143 bits (361), Expect = 9e-33,   Method: Composition-based stats.
 Identities = 65/321 (20%), Positives = 114/321 (35%), Gaps = 31/321 (9%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRS-- 57
           ME +DV ++G GPAG + A+  A   ++VI L+           KPCG   +     +  
Sbjct: 1   MEEWDVIVVGGGPAGLSAAKFSAELGLKVILLEAYSDIRAW---KPCGEGTSKTTFETAG 57

Query: 58  FIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIP----A 113
                  +  ++       S K V++              IN+   DL++  L      A
Sbjct: 58  IEPKPGVVSNELSMKVYAPSGKYVEIPLH--------GYAINK---DLFLLELAKKAYLA 106

Query: 114 SVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRK 173
             E+        + +E+    V        + +  + +VGADG NS V +    D++   
Sbjct: 107 GAEIRVGERVESVLKENG--RVCGVKTAKGETLRGKVVVGADGYNSTVAKSSGLDNRTEL 164

Query: 174 YVAIQQWFAEKHPVPFYSC-IFDNSI-TNCYSWSISKDGYFIFGGAYPMKDGQTRFTT-- 229
               Q          + S  I+  S+    Y+W   KD      G          +    
Sbjct: 165 IPTYQYKMVGVELDSYNSGRIYVGSMAPGGYAWIFPKDDQVANVGIGVRPGSPKLYLDKF 224

Query: 230 LKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYA 289
           +KE+   F+      V       + P          D   LIG+AAG +   +  GI  +
Sbjct: 225 IKERPEIFRKAKIIGVGGY----VVPIGGLAREYIGDGVILIGDAAGMVIPFTGAGIHSS 280

Query: 290 LDSTDILRSVLLKQPEKLNTA 310
           + +   +   + +  EK +T+
Sbjct: 281 IAAGKAVSRTIAEALEKGDTS 301


>UniRef50_Q8TUV8 Digeranylgeranylglycerophospholipid reductase 2 n=2
           Tax=Methanopyrus kandleri RepID=GGR2_METKA
          Length = 396

 Score =  143 bits (361), Expect = 9e-33,   Method: Composition-based stats.
 Identities = 60/351 (17%), Positives = 105/351 (29%), Gaps = 28/351 (7%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            FDV ++G GPAGS  A   A     V+ L++K + G     K C   ++          
Sbjct: 2   EFDVVVVGAGPAGSVAAWAAAEAGCDVLILERKAEIG---VPKQCAEGISAHG---LEHA 55

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYH-- 119
           G+    + IA     ++  +                + R  FD W+      +       
Sbjct: 56  GIEPQDEWIATEISRAL--IYAPNGKEFEVPGDGYVLERRVFDKWLVVRAVEAGAEVELL 113

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRH---LYPDHQIRKYVA 176
               R +  E     V +  +     + AR ++ ADG  S + R    +     +     
Sbjct: 114 AHARRALLDEGRVVGVEYEGEDGVHEVRARIVIAADGIESRIGRTAGLVPSLKPVEMCTC 173

Query: 177 IQQWFAEKHPVPFYSCIFDNS--ITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKM 234
            Q            +  F ++      Y W   K       G             LK   
Sbjct: 174 AQYEMVGVDVEEDATHFFVDAEFFPGGYFWIFPKGEGRANVGLGIRGSESEPGDALKVLN 233

Query: 235 SAFQFQFGKTVKSEKCTVLFPSRWQDFVCGK------DNAFLIGEAAGFISASSLEGISY 288
            A +     +        +  +     VCG       D   L+G+AA  ++  +  G+  
Sbjct: 234 RALEDHELISEAVADAVPVEVNVGGVPVCGPVERTYGDGILLVGDAARQVNPLTGGGLHT 293

Query: 289 ALDSTDILRSVLLKQPEK------LNTAYWRATRKLRLKLFGKIVKSRCLT 333
           +L    I   V  +  E+          Y     +   K F   +K+  + 
Sbjct: 294 SLVCGRIAGEVAAEAIEEDDTSASFLKRYQDRWEEEFGKTFKYALKASKIF 344


>UniRef50_A9A398 Geranylgeranyl reductase n=4 Tax=Thaumarchaeota RepID=A9A398_NITMS
          Length = 402

 Score =  142 bits (358), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 66/332 (19%), Positives = 118/332 (35%), Gaps = 27/332 (8%)

Query: 4   FDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +D+ ++G GPAGS+ A   +   ++VI ++K+        +    G+        F    
Sbjct: 5   YDLVVVGGGPAGSSAAYTASKNGLKVILIEKEESIAESVRT---SGVTWIQNIEEF---- 57

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPA-SVEVYHDS 121
             +P D     + F   + +   S+     RS +   R  +  W+ S   A   E+  ++
Sbjct: 58  -GIPEDCYNPVKNFEFYSPNNKVSIGDTVARSAVLDVRKTY-RWLASQAEAQGTEIVVNT 115

Query: 122 LCRKIWREDDK--WHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQ 179
             + + +++      V    +  E     + ++ A G  S V + +    Q  ++ A  +
Sbjct: 116 TVKDVIKDESGKIIGVKAIQNEKEIEFFGKVVIDASGFQSTVAKSMGFVKQWERFGAGAE 175

Query: 180 WFAEKHPVPFYSC---IFDNSITNCYSWSIS-KDGYFIFGGAYPMKDGQ----TRFTTLK 231
           + A+   V   +    + +      Y+W     D     G      D       R   L 
Sbjct: 176 YEAKVEHVKADTWWLMVGEKYSPAGYAWIFPLGDNIARIGVGIGKPDSPVDPTARLKELI 235

Query: 232 EKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALD 291
           E         GK    E    L P+         DN  L+G++AG  +   LEGI YA+ 
Sbjct: 236 ENKEGPIANLGKIEPIEFHYGLIPNDGLSRKTVYDNLILVGDSAGQANPLVLEGIRYAIK 295

Query: 292 STDILRSVLLKQ------PEKLNTAYWRATRK 317
              I   V  K        EK  + Y    +K
Sbjct: 296 FGRIAGDVASKAIKANDTSEKKLSEYEDNWKK 327


>UniRef50_A3CW88 Geranylgeranyl reductase n=1 Tax=Methanoculleus marisnigri JR1
           RepID=A3CW88_METMJ
          Length = 365

 Score =  142 bits (357), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 63/339 (18%), Positives = 106/339 (31%), Gaps = 22/339 (6%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTE---GFSKPCGGLLAPDAQRS 57
              DV ++G GPAGS  AR  A   + V+ +DK+   G     G       +LA     +
Sbjct: 3   NRCDVVVVGAGPAGSTAARYAAKTGLDVLLIDKRRTIGVPVCCGEFNASSEVLASVLPNA 62

Query: 58  FIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLI-PASVE 116
              D L      +   +I     V         ++     ++R AFD  +         E
Sbjct: 63  SGLDELFPVDPGLIRREIRGAVAVS-PGGREYEFELPGYTVDRDAFDRHLADAAVREGAE 121

Query: 117 VYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVA 176
           +  D+                R       + AR +V ADG  S V R    +       A
Sbjct: 122 LLPDTKFLGREGS--------RVTTTRGEVEARVVVAADGPLSRVCRSAGMERSAVLAPA 173

Query: 177 IQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSA 236
           I      +          +      Y+W   K G    G     +D           + A
Sbjct: 174 ITCRVDGEFGDRLKFFFGNRIAPGGYAWVFPKRGCANAGLGVQKRDVPVPV-----LLRA 228

Query: 237 FQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDIL 296
           F    G + +  +     P         ++N   +G+AAG + AS+  GI+ A+    + 
Sbjct: 229 FLASQGFSARDVQA-GFVPVSGPIRETVRENVLAVGDAAGHVVASNGGGIAPAMICGRLA 287

Query: 297 RSVLLKQPE--KLNTAYWRATRKLRLKLFGKIVKSRCLT 333
                      +   AY    R    +      +++ + 
Sbjct: 288 GLAAANHLLRGEPLAAYEWEWRSAIGRELLAAARTKRMA 326


>UniRef50_A3MV77 Geranylgeranyl reductase n=5 Tax=Thermoproteaceae
           RepID=A3MV77_PYRCJ
          Length = 367

 Score =  141 bits (356), Expect = 3e-32,   Method: Composition-based stats.
 Identities = 72/292 (24%), Positives = 105/292 (35%), Gaps = 33/292 (11%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           +DV ++G GPAGS  A           +  + Q   E   KPCGG L P  QR     G+
Sbjct: 12  YDVVVVGAGPAGSTAAIVAGRLGLKAVVVDRLQPPRE---KPCGGGLTPRTQRLLNALGV 68

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRH-AFDLWMKSLIPASVEVYHDSL 122
             PV    +  +        AA      +R  I + R   FD  +     + VE   D  
Sbjct: 69  EYPVYGRCDTIVVQ------AAGYRYEMRREPILVTRRPDFDYALLK--QSGVEYVKD-- 118

Query: 123 CRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFA 182
             ++    D   V     G         ++GADGA S V R +   +          +  
Sbjct: 119 --QVVEVRDNTAV-----GRAGEYAGEVIIGADGATSAVARSIGVYNYKGHKSHGIAYMT 171

Query: 183 EKHPVPFYSCIFD-----NSITN-CYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSA 236
                P   CI D     N++    Y+W     G    G       G  ++  L+E ++ 
Sbjct: 172 IASGPPRDICIIDFDAVINTVGKVGYAWIFPLKGGANIGAG----TGWGKWLDLRELVAK 227

Query: 237 FQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISY 288
           +    G   K  +      S       G+ N  L GEAAG + A++ EGI Y
Sbjct: 228 YAESAGY--KPGQILGHPLSLGHVEGVGRGNVILAGEAAGLVDATTGEGIYY 277


>UniRef50_Q30ZB0 Geranylgeranyl reductase n=1 Tax=Desulfovibrio desulfuricans subsp.
           desulfuricans str. G20 RepID=Q30ZB0_DESDG
          Length = 383

 Score =  141 bits (356), Expect = 3e-32,   Method: Composition-based stats.
 Identities = 62/310 (20%), Positives = 112/310 (36%), Gaps = 20/310 (6%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           +D  ++G GP G++ A  LA     + +      G     K CGGLL   +  +F+RD  
Sbjct: 9   YDAVVVGGGPCGASAAFTLARNGYTVMVID---AGKFPRFKLCGGLLTGKS-TAFLRDCF 64

Query: 64  TLPVDVIANP------QIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEV 117
            +    +A        +            +  +    +  + R  FD  +   + A+  V
Sbjct: 65  GMDASCLARAGALEGCENSYHIYAGGRRIVAGSNGSPFYFVRRDRFDSRLLKSVAAAGAV 124

Query: 118 YHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHL--YPDHQIRKYV 175
             +    K+   D +   +   DG    + A +++ ADG +S VR+ +     H +R+ V
Sbjct: 125 VREG--TKVVHADCRTGKVHCHDG--SSVCAEFIIAADGVHSTVRKAVCGGLRHSVRQAV 180

Query: 176 AIQQWFAEKHPVPF--YSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEK 233
           A++     +H         +    +   Y W        + G    +  G+     L+  
Sbjct: 181 AVEVAVPRRHMPQGVQLPSVHLGLLQRGYGWLFPNRRNIVAGVGGLLCRGEHPARVLRTL 240

Query: 234 MSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDST 293
           +     Q G   +    T   P              L G+AAGF  A   EGI YA+ S 
Sbjct: 241 LCGCGVQAGHIPQPRGYT--LPFGGHLRRPFSGRVLLAGDAAGFADAVFGEGIYYAMLSG 298

Query: 294 DILRSVLLKQ 303
            +    +++ 
Sbjct: 299 SLAAQAVMQA 308


>UniRef50_C6HZ38 Geranylgeranyl reductase n=1 Tax=Leptospirillum ferrodiazotrophum
           RepID=C6HZ38_9BACT
          Length = 414

 Score =  141 bits (355), Expect = 3e-32,   Method: Composition-based stats.
 Identities = 69/349 (19%), Positives = 116/349 (33%), Gaps = 28/349 (8%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           H D A++GLGPAGS   R LA          +        +KPCGG ++           
Sbjct: 16  HVDAAVVGLGPAGSTALRLLASAGISCIGIDRSH---FPRNKPCGGGVSARTLPLLPPGL 72

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLI-PASVEVYHDS 121
           L      I +    + +                  + R  FD  +      A  +V    
Sbjct: 73  LDEIPHQITSGISLTYRGGPSQNQDFGR--PIAYQVRRDQFDAALLDAAYRAGGQVMTGV 130

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQ--------IRK 173
                 RE  ++ ++       + I A  +  ADGA S + R L PD          +R 
Sbjct: 131 ETVSARREGREFVIV----ADHRVIRALSVFAADGATSRILRDLDPDSSRHVRENPSLRP 186

Query: 174 YVAIQQWFAEKHPVPFYSCIFD-NSITNCYSWSISK-DGYFIFGGAYPMKDGQTRFTTLK 231
           + + + +   ++P+       D   ++  Y+WS  K D  +  G A  +           
Sbjct: 187 FTSAEAFGDLRNPIDDRHVGIDLGLVSGGYAWSFPKKDSSWGLGVAGFLGPLANPRKEFA 246

Query: 232 EKMSAFQFQFGKTVK-SEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYAL 290
             + + Q   GK    +         R           FL+G+A G +     EGI YA+
Sbjct: 247 RYLESRQATVGKAEVLTWPLPNYRSVRHGRI----SGLFLVGDAGGILDPFLGEGIYYAI 302

Query: 291 DSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRK 339
            S       L+ +  + + A       L  + + + VK      P   +
Sbjct: 303 LSATRGAEALIHELSRKDIA-PETAAGLASQAYARFVKGTL--WPDFAQ 348


>UniRef50_Q9CA67 Geranylgeranyl diphosphate reductase, chloroplastic n=216
           Tax=cellular organisms RepID=CHLP_ARATH
          Length = 467

 Score =  140 bits (352), Expect = 8e-32,   Method: Composition-based stats.
 Identities = 59/349 (16%), Positives = 116/349 (33%), Gaps = 38/349 (10%)

Query: 21  KLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKT 80
              G ++ I +++K         KPCGG +       F    L +    +   ++ S   
Sbjct: 74  LAQGGIETILIERKMDNC-----KPCGGAIPLCMVGEFN-LPLDIIDRRVTKMKMISPSN 127

Query: 81  VDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLCRKIWREDD--------- 131
           + V    T         + R   D +++     S     + L  K+   ++         
Sbjct: 128 IAVDIGRTLKEHEYIGMVRREVLDAYLRERAEKSGATVINGLFLKMDHPENWDSPYTLHY 187

Query: 132 -KWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEKHPVPFY 190
            ++     A G ++ +    ++GADGANS V + +         +A Q+          Y
Sbjct: 188 TEYDGKTGATGTKKTMEVDAVIGADGANSRVAKSIDAGDYDY-AIAFQERIRIPDEKMTY 246

Query: 191 S------CIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQ-TRFTTLKEKMSAFQFQFGK 243
                   + D+   + Y W   K  +   G       G   +F       +  +   GK
Sbjct: 247 YEDLAEMYVGDDVSPDFYGWVFPKCDHVAVGTGTVTHKGDIKKFQLATRNRAKDKILGGK 306

Query: 244 TVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQ 303
            ++ E   +    R +          L+G+AAG+++  S EGI +A  S  +    +++ 
Sbjct: 307 IIRVEAHPIPEHPRPRRL---SKRVALVGDAAGYVTKCSGEGIYFAAKSGRMCAEAIVEG 363

Query: 304 P--------EKLNTAYWRATRKLR---LKLFGKIVKSRCLTAPALRKWI 341
                    E     Y     K      ++   + K    + PA   ++
Sbjct: 364 SQNGKKMIDEGDLRKYLEKWDKTYLPTYRVLDVLQKVFYRSNPAREAFV 412


>UniRef50_D1X0J5 Geranylgeranyl reductase n=1 Tax=Streptomyces sp. ACT-1
           RepID=D1X0J5_9ACTO
          Length = 892

 Score =  139 bits (350), Expect = 1e-31,   Method: Composition-based stats.
 Identities = 73/382 (19%), Positives = 130/382 (34%), Gaps = 47/382 (12%)

Query: 6   VAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           V ++G GPAGS+ A  LA     VI L+K          K CG  L P A    IR G+ 
Sbjct: 464 VIVVGAGPAGSSAAYHLARAGVDVILLEK----ARFPREKVCGDGLTPRAVHQLIRMGVD 519

Query: 65  LPVDVIANPQIFSV----KTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVYH 119
           +        +          V +       Y    ++ +RH FD  + +  + A   +Y 
Sbjct: 520 ITAPGWTRSRGMRWVAGEHRVRIDWPALGRYPDFGLSRSRHDFDDILARHAVAAGARLYS 579

Query: 120 DSLCRK--IWREDDKWHVIFRADGWEQ----HITARYLVGADGANSMVRRHLYPDHQIRK 173
                +    R      V   +D  E        A  ++ ADGA++ +   L  +   R+
Sbjct: 580 GWKAERPLTDRAGRVTGVAASSDSAEVPEPVDFHAPVVIAADGASARLALALGLERDPRR 639

Query: 174 YVAI--QQWFAEKHPV--------PFYSCIFDNSITNCYSWSIS-KDGYFIFG-GAYPMK 221
            +A   ++++                            Y W     DG    G GA P +
Sbjct: 640 QIATAARRYYRSPERSREEYLELWADLRFPGGGPYLPGYGWIFPMGDGRVNVGLGALPHR 699

Query: 222 D--GQTRFTTLKEKMSAFQFQFGKTVKSEKCTVL---FPSRWQDFVCGKDNAFLIGEAAG 276
                    TL + ++    ++G   ++ +  V     P  +           L+G++ G
Sbjct: 700 RHGKADLRATLDQWLARTPEEWGLREENAEGPVRSAALPLGFNRHPLYARGLLLVGDSGG 759

Query: 277 FISASSLEGISYALDSTDILRSVLLKQPEKLNTA--------YWRATRKLRLKLFGK--- 325
            +S  + EGI+ A+++ ++              A        Y     +   + +     
Sbjct: 760 MVSPWNGEGIAQAMEAGEVAAETAALALAHPRGARREQVLRGYPVEMNRRWGRYYRLGNT 819

Query: 326 ---IVKSRCLTAPALRKWIMRS 344
              +V SR    P L +++M S
Sbjct: 820 AADLVFSRSGFQPVLNRYVMGS 841


>UniRef50_Q9U641 Conditioned medium factor receptor 1 n=1 Tax=Dictyostelium
           discoideum RepID=CMFB_DICDI
          Length = 510

 Score =  139 bits (349), Expect = 2e-31,   Method: Composition-based stats.
 Identities = 67/368 (18%), Positives = 123/368 (33%), Gaps = 36/368 (9%)

Query: 4   FDVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +DVA IG GP+GS L   LA +  +V  L+KK         K CG  +A  AQ      G
Sbjct: 81  YDVATIGAGPSGSVLGYYLAREGRKVALLEKK----VFPRDKYCGDAVATMAQDILREMG 136

Query: 63  LT---LPVDV---IANPQIFSVKTVDVAASLTRNYQRSY-------ININRHAFDLWMKS 109
           +    +  D+     N    S        +  +  +R         I + R   D  +  
Sbjct: 137 VMKELVDEDLGHFAQNGGFVSPNGNSFIGNSAKELKRDAKYNRGAVIAVKRIVLDEKVAK 196

Query: 110 LIP-ASVEVYHDSLCRK--IWREDDKWH---VIFRADGWEQHITARYLVGADGANSMVRR 163
                  ++  ++        R    W    V    +  +    AR LV ADG+ S   R
Sbjct: 197 AAKRMGADLKENTTVENATFDRSTGVWTINCVDSEDNTKKIVYRARVLVCADGSPSNAAR 256

Query: 164 HLYPDHQIRKYVAIQQWFAEKHPVPFYSCIF--DNSITNCYSWSISKDGYFIFGGAYPMK 221
            L   H     +  + +        +   +F   + +    +          +  AY + 
Sbjct: 257 QLGYVHTEPNGICSRAYVKNNTTFRYDGVVFYPPSLLPGYCAIIREARDELNYL-AYIIP 315

Query: 222 DGQTRFTTLKEKMSAF-------QFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEA 274
            G+     L +    +           G     E+                D+  ++G+A
Sbjct: 316 GGKVTNDDLSKYHHQYMTEDPFISAALGPNPDIERMKAAPLRLGGIKKSYDDHLLIVGDA 375

Query: 275 AGFISASSLEGISYALDSTDILRSVLLKQPEKLNTAY--WRATRKLRLKLFGKIVKSRCL 332
           AGFI   + EGI YA++ + +    L++   + + ++   +  +   +  FG        
Sbjct: 376 AGFIDPLTGEGIQYAMEGSRLASLALIQAFNERDLSHQSLKRYQDFWMAKFGHEFSMSMT 435

Query: 333 TAPALRKW 340
            +  L ++
Sbjct: 436 MSLFLYRF 443


>UniRef50_Q46C42 Geranylgeranyl reductase n=5 Tax=Methanosarcina RepID=Q46C42_METBF
          Length = 391

 Score =  138 bits (348), Expect = 2e-31,   Method: Composition-based stats.
 Identities = 55/327 (16%), Positives = 111/327 (33%), Gaps = 27/327 (8%)

Query: 24  GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTVDV 83
             +  + ++K++        KPCGG L+             LP  +I             
Sbjct: 23  RGLLTLLIEKEN----FPRYKPCGGALSSYGLSCLD---FKLPESIIERNIPKVGVYFRD 75

Query: 84  AASLTRNYQRSYININRHAFDLWM-KSLIPASVEVYHDSLCRKIWREDDKWHVIFRADGW 142
                       + ++R  FD ++ +    A +EV+       +  ++D   V       
Sbjct: 76  RFVEGMKENNLALLVSRKVFDNFLLEKARGAGIEVHTGEEVLDLVEKEDFVEVRTT---- 131

Query: 143 EQHITARYLVGADGANSMVRRHLYPDHQIRKYVA--IQQWF----AEKHPVPFYSCIFDN 196
           +      +++ ++G+   ++  + P  +I +Y    + +        ++  P    I   
Sbjct: 132 DNTYLGSFVLISEGSGGTLKYKVRPRDKITEYGLGLVSEIPDDDEVIRNRFPGTINIHFG 191

Query: 197 SITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPS 256
                Y W     GY+  G     +  +    TL + +          V+S     + P 
Sbjct: 192 VAKGGYGWIFPHAGYYSAGIVGAAQYLEHPKKTLLDFLEENGLSGDFPVRSH----VIPK 247

Query: 257 RWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSV---LLKQPEKLNTAYWR 313
                        L G+AAGF+ A + EG+SYA+ S  +       L+    KLN+   +
Sbjct: 248 GGIKRKILNSRLLLSGDAAGFVDAFTGEGLSYAIRSGQLAAETVADLVMYSLKLNS--LK 305

Query: 314 ATRKLRLKLFGKIVKSRCLTAPALRKW 340
           A      + FG  + S       + ++
Sbjct: 306 AYEFSCRQEFGNYLSSSLKLDKIMHRF 332


>UniRef50_C3XVJ7 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
           RepID=C3XVJ7_BRAFL
          Length = 485

 Score =  138 bits (347), Expect = 3e-31,   Method: Composition-based stats.
 Identities = 73/380 (19%), Positives = 122/380 (32%), Gaps = 34/380 (8%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
             +DVA++G GPAGS L   LA   +   L +K +       K CG  +   A    +  
Sbjct: 61  GFYDVAVVGAGPAGSTLGYYLAKAGRNCLLLEKKK---FPRDKYCGDAVCKTAIEILMDM 117

Query: 62  GL--TLPVDVIANPQIFSVKTVDVAASLTRNYQR------SYININRHAFDLWMKSLIP- 112
           G+   L  +  A              S     +       + +   R   D  +      
Sbjct: 118 GIYEKLIKENKARIADAGGLCSPGGLSYIGRSKEILGEVPAALACKRWWLDEAIAMAAKR 177

Query: 113 ASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIR 172
           A   +  +S  R    +          +  ++   AR LV ADGA S +   L    +  
Sbjct: 178 AGAHLMENSGVRDAVFDAKAGLWTVYLEDSDKSYKARILVCADGAPSKLATKLGIVKRPP 237

Query: 173 KYVAIQQWFA-EKHPVPFYSCIFDNS-ITNCYSWSISKDG-------YFIFGGAYPMKDG 223
                + +     H      CIF +  +   YS              Y I G      D 
Sbjct: 238 DGSCSRAYVESGTHKFKADGCIFYHRDMLPGYSALFRHPNNELNYCVYLIPGNPKVTNDD 297

Query: 224 QTRFTT-LKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASS 282
              +   L ++        G   K E+          + V   D+  ++G+AAG I   +
Sbjct: 298 LPYWHNFLMKQDPNISKSLGPGAKLERMKAASLRLGGEPVSHGDHVLVVGDAAGMIDPMT 357

Query: 283 LEGISYALDSTDILRSVLLKQPEKLN------TAYWRATRKLRLKLFGKIVKSRCLTAPA 336
            EGI +A+++  +    L +     N        Y  A     +  FG   K        
Sbjct: 358 GEGIHHAMEAGKMAAKFLDEAMHHGNYDKDVMKLYHEAW----MDKFGSDFKWSFAICQL 413

Query: 337 LRKW--IMRSGVAHIPQLKD 354
           L ++  ++ +  A I +  D
Sbjct: 414 LYRFPILLDAATAAIARKGD 433


>UniRef50_C0ZA99 Electron transfer flavoprotein-quinone oxidoreductase n=4
           Tax=Firmicutes RepID=C0ZA99_BREBN
          Length = 431

 Score =  137 bits (344), Expect = 7e-31,   Method: Composition-based stats.
 Identities = 62/337 (18%), Positives = 112/337 (33%), Gaps = 35/337 (10%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           E FDV I+G GPAG+A A  LA     V+ +++    G++      GG+L        I 
Sbjct: 3   EKFDVIIVGAGPAGTACAYTLAKAGVNVLLMERGEYPGSKNVM---GGVLYRKTMEDIIP 59

Query: 61  DGL-TLPVDVIANPQIF------SVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPA 113
           +     PV+     Q F      S                +   + R  FD W       
Sbjct: 60  EFYKEAPVERPIVEQRFMMLDRESAINFSYKGMEWAQEPYNNFTVLRAKFDQWFADKAVQ 119

Query: 114 SVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRK 173
              +  +         ++   V  + D  +  + A  +V ADG NS++ + L    + R 
Sbjct: 120 QGALLLNETVALQCIVENGKVVGVKTDRPDGDLYADVVVLADGVNSLLAKSLGFHKEFRP 179

Query: 174 ---YVAIQQWFA--------EKHPVPFYSC---IFDNSITN--CYSWSISKDGYFIFGGA 217
               +A+ +             +    + C   IF +S       +W  +       G  
Sbjct: 180 DEVALAVMEVLKLDRKIIEDRFNLEGDHGCTIEIFGDSTKGILGTAWLYTNKDSLNIGVG 239

Query: 218 YPM----KDGQTRFTTLK--EKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCG--KDNAF 269
             +    K+    +  L   +     +       + E    L P      +     +   
Sbjct: 240 TMLSGLIKNKIKPYELLDYVKNHPMIRPYIQGCEQQEYLAHLIPEGGYRSIPKIVGNGVL 299

Query: 270 LIGEAAGFISASSLEGISYALDSTDILRSVLLKQPEK 306
           ++G+AA  ++A   EG + A+ S  +    +L   E 
Sbjct: 300 VVGDAAQLVNAIHREGSNMAMASGVMAAETILAAKEA 336


>UniRef50_A1RZG7 Geranylgeranyl reductase n=1 Tax=Thermofilum pendens Hrk 5
           RepID=A1RZG7_THEPD
          Length = 423

 Score =  137 bits (344), Expect = 7e-31,   Method: Composition-based stats.
 Identities = 76/370 (20%), Positives = 122/370 (32%), Gaps = 44/370 (11%)

Query: 4   FDVAIIGLGPAGSALARKLAGK-MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +D+ ++G GPAGS+ A   A   + V+ L+K    G     K CGG ++   Q S    G
Sbjct: 2   YDLVVVGGGPAGSSAAIAAARAGLSVVVLEK----GERNRDKYCGGGISVLTQNSLRELG 57

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQ-RSYININRHAFDLWMKSLIPA-SVEVYHD 120
               ++   N     V  +     L        Y  + R  FD  ++ L  +    V H 
Sbjct: 58  AAEALETFENYAEGHVLVLPGEKVLVDAIPGLGYGLVRRSVFDAKLRELAESYGATVKHG 117

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLY----PDHQIRKYVA 176
                I  + DK  V  R     + +  RY V A GA +   R L         +     
Sbjct: 118 FEASSITVDGDKVVVRSR---KGEVVEGRYAVVATGAGNFPERALGFPPLRPENLGHCWG 174

Query: 177 IQQWFAEKHPVPFY--------SCIFDNSITNCYSWSISKDGYFIFGGAYPMKD----GQ 224
            +  +     V  +          +    +T  Y W   K  +   G    + +    G+
Sbjct: 175 TEAEYPVSAEVERWRHEYGFTPIFLMFGFVTYGYMWVFPKRNHMNVGMGTTLAESARYGR 234

Query: 225 TRFTTLKEKMSAFQFQFGKTVKSEKCTV----LFPSRWQDFVCGKDN-AFLIGEAAGFIS 279
                    +     + G   +  +  V    L P + +     ++    L G+AAGF+ 
Sbjct: 235 LHLEGFARGLE-LARRMGILSEPGRLRVDRSWLIPGKPRAVTYSQERRVLLAGDAAGFVH 293

Query: 280 ASSLEGISYALDSTDILRS----VLLKQPEKLNTAYWRATRKLR--------LKLFGKIV 327
             + EGIS A+ S  +        L K+   L   Y                LKL   + 
Sbjct: 294 PLTGEGISGAVRSGRLAAETVKQALDKEDPGLLKEYEAKWWADFGEDAYAYGLKLTRLMY 353

Query: 328 KSRCLTAPAL 337
            S  L    L
Sbjct: 354 SSPALQRLGL 363


>UniRef50_D2QMD3 Monooxygenase FAD-binding protein n=5 Tax=Bacteroidetes
           RepID=D2QMD3_9SPHI
          Length = 375

 Score =  136 bits (342), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 63/366 (17%), Positives = 136/366 (37%), Gaps = 33/366 (9%)

Query: 5   DVAIIGLGPAGSALARKLAGK-MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           DV IIG G AG   +  L    +QV+ L+K+         K CG  ++ +        G+
Sbjct: 6   DVIIIGGGLAGLTASIHLTRADVQVLLLEKQD----YPQHKVCGEYISNEVLPYLQHLGV 61

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLC 123
            +  ++  +     + +     ++          ++R+  D ++     ++      +  
Sbjct: 62  DID-ELNPSRISRFLLSTAAGKTVESTLPLGGFGVSRYTLDQFLADKAKSAGVDLRQADV 120

Query: 124 RKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIR--KYVAIQQWF 181
             I   ++ + V       EQ  TA+ ++GA G  S + + L      R   ++ ++  +
Sbjct: 121 TDIQFANNVFTVTTAT---EQTYTAKIVLGAYGKRSQLDKRLNRPFASRESGWLGVKAHY 177

Query: 182 AEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQ--TRFTTLKEKMSA--- 236
             +   P       N        S  ++G          +  +      + ++ +     
Sbjct: 178 --QADFPDDLVALHNFDGGYCGLSQVENGIVNACYLVNYRSFKAVKNIDSFQQHVLRKNP 235

Query: 237 FQFQFGKTVKSEKCTVLFPSR--WQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTD 294
           F  +F  T        L  S+  +      +++  + G+ AG I      G++ A+ S  
Sbjct: 236 FLNEFFATATPLFARPLTISQISFDKKSPVENHILMCGDTAGLIHPLCGNGMAMAIHSAK 295

Query: 295 ILRSVLLK----------QPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRS 344
           ++  ++++            EK  T+ W A  + RL L G+I ++  L  PA+   I++S
Sbjct: 296 LVSELVIQFFNGKLANRAALEKQYTSGWSAEFRTRL-LTGRIAQTVLLY-PAITNVILKS 353

Query: 345 GVAHIP 350
            +   P
Sbjct: 354 -LQRTP 358


>UniRef50_A8JAG1 Predicted protein n=1 Tax=Chlamydomonas reinhardtii
           RepID=A8JAG1_CHLRE
          Length = 494

 Score =  136 bits (342), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 55/352 (15%), Positives = 106/352 (30%), Gaps = 37/352 (10%)

Query: 4   FDVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +D  I+G GP+GS  A  ++    +V  L+K+    T    K CG  +   A R     G
Sbjct: 63  YDAVIVGAGPSGSVCAYYMSRGGAKVALLEKE----TFPRDKYCGDAVCTPAIRILEDMG 118

Query: 63  LTLPVDVIANPQ--------IFSVKTVDVAASLTRNYQRSYIN-INRHAFDLWMKSLIPA 113
           +    +++AN +          S                +    + R   D+ +      
Sbjct: 119 VL--QELVANNEAHFADAGGFVSPNGTSYIGVSKAKLGEAACCAVKRINLDIRVAKNAAR 176

Query: 114 SVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRK 173
           +     +         D    +          +  R LV ADGA S +   L    +  K
Sbjct: 177 AGADLKEKFEVTGATFDKAAGLWTVTSATGTVVRGRVLVCADGATSRLATKLGYCTEAPK 236

Query: 174 YVAIQQWFAEKHPVPFYS--CIFDNSITNCYSWSISKDG------YFIFGGAYPMKDGQT 225
            +  + +         +   C +       Y+             Y++         G+ 
Sbjct: 237 GICSRAFIEGGTHNTNFDGVCFYPKWSLPGYAAIFRHPNDELNFCYYLIPCGKEGYCGEV 296

Query: 226 RFTTLKEKMSAFQFQFGK----------TVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAA 275
           + + L  ++     +              ++  +   L            D+  +IG+AA
Sbjct: 297 KESDL-ARLHNDAIKADPFISKAIGPNAKIERMRAASLRLGGQGLKTTFDDHLLIIGDAA 355

Query: 276 GFISASSLEGISYALDSTDILRSVLL--KQPEKLNTAYWRATRKLRLKLFGK 325
           G I   + EGI  A+         LL  +     +    +       +L+G 
Sbjct: 356 GHIDPYTGEGIHTAMMGGKAAAESLLAMRSTGDFSKQSTKQYEAEWRRLYGH 407


>UniRef50_UPI00018742EF geranylgeranyl reductase n=1 Tax=Corynebacterium amycolatum SK46
           RepID=UPI00018742EF
          Length = 426

 Score =  135 bits (340), Expect = 2e-30,   Method: Composition-based stats.
 Identities = 63/330 (19%), Positives = 108/330 (32%), Gaps = 41/330 (12%)

Query: 7   AIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTL 65
            I+G GP GSA A   A     V  +D +         K CG  L P A     R GL  
Sbjct: 2   LIVGAGPTGSAAAIHAARAGFSVTVVDSQ----RFPRDKTCGDGLTPRAIAELRRLGL-- 55

Query: 66  PVDVIANPQIFSVK--------TVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVE 116
             +++   +   +K        T       +  +      ++R   D ++  +   A  +
Sbjct: 56  DDELLRRNRNRGLKLHGFGGSITAPWPDDASGTFPAVGSAMSRVELDTFLLNAAADAGAQ 115

Query: 117 VYHDSLCRKI---------WREDDKWHVIFR-ADGWEQHITARYLVGADGANSMVRRHLY 166
           V+     RK+          R      V     +G    I+AR+L+ ADG  S V + L 
Sbjct: 116 VFDGVAARKVVLGALSSGGTRGHGVREVELSDREGKPHTISARWLLVADGVRSTVGKQLG 175

Query: 167 P--DHQIRKYVAIQQWFAEKHPVPFYSCIF--------DNSITNCYSWSIS-KDGYFIFG 215
                     VA + + +          I         +      Y W      G    G
Sbjct: 176 RAWHRDSVFGVAARSYVSFDSVDVADDWIHSHLELRDSEGQTHPGYGWIFPLGAGQANVG 235

Query: 216 GAYPMKDGQTRFTTLKEKMSAFQFQFGKTVK----SEKCTVLFPSRWQDFVCGKDNAFLI 271
                   +   T +K+ +  +  Q  +  +        + L P           N  L+
Sbjct: 236 CGALATSARPARTNVKKLLREYHGQVREQWQMSEPEHVTSALLPMGGAVSNVAGPNWALL 295

Query: 272 GEAAGFISASSLEGISYALDSTDILRSVLL 301
           G+AA  ++  + EGI Y ++S  +   ++ 
Sbjct: 296 GDAACLVNPLNGEGIDYGMESARLAVELIS 325


>UniRef50_A3HTX2 FAD dependent oxidoreductase, putative n=1 Tax=Algoriphagus sp. PR1
           RepID=A3HTX2_9SPHI
          Length = 370

 Score =  134 bits (337), Expect = 5e-30,   Method: Composition-based stats.
 Identities = 66/371 (17%), Positives = 134/371 (36%), Gaps = 36/371 (9%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           M+ ++V I+G G AG   +  LA   + + L +K       F + CG  ++ +     +R
Sbjct: 1   MDKYEVIIVGGGLAGLVASFLLAKGGKKVLLIEKK---NYPFHRVCGEYVSNEVYEFLMR 57

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTR-NYQRSYININRHAFDLWMKSLIPA-SVEVY 118
           + L     V   P++      D + +  +         I+R   D ++   +        
Sbjct: 58  EELLP--TVYDLPRMTHFLFSDTSGNTAKVPLGLGGFGISRFVLDAYLFQRVKEMGASSQ 115

Query: 119 HDSLCRKIWRE--DDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVA 176
             +   K+  +  ++++HV  R     +   A Y++GA G  S + + L      ++   
Sbjct: 116 TGATVEKLTFDTSENQFHVGLRT---GEEYRADYVIGAFGKRSKLDKTLQRPFIEKRSPY 172

Query: 177 IQQWFAEKHPVPFYSCIFDNSITNCYSWSIS---KDGYFIFGGAYPMKDGQTRFTTLKEK 233
           I   +  K      + +  N        +     K      G    ++   +     KE 
Sbjct: 173 IGVKYHIKTEFDSSAVVLHNFEGGYCGLNAIEEGKGNLCYLGKREALRHFGSLEAMEKEV 232

Query: 234 MSAFQFQFGKTVKSE----KCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYA 289
           +           +SE    K  V+    ++     +++  + G++AG I+     G++ A
Sbjct: 233 LWKNPHLKKLFTESEFLLEKPEVINEINFEKKQPVENHILMAGDSAGLITPLCGNGMAMA 292

Query: 290 LDSTDILRSVLL--KQPEKLNTAY---WRATRKLRL-------KLFGKIVKSRCL----- 332
           + S  +    +L  K  E +  +Y   W++  + RL       +LFG    S        
Sbjct: 293 IHSGKLAAEAILEGKSREGVEKSYEKVWKSKFERRLWVGRNTQRLFGNQSASGFAQTLIS 352

Query: 333 TAPALRKWIMR 343
             P   K I+R
Sbjct: 353 KLPGFAKLIIR 363


>UniRef50_C8QXS9 Monooxygenase FAD-binding n=1 Tax=Desulfurivibrio alkaliphilus AHT2
           RepID=C8QXS9_9DELT
          Length = 347

 Score =  133 bits (335), Expect = 8e-30,   Method: Composition-based stats.
 Identities = 75/337 (22%), Positives = 121/337 (35%), Gaps = 34/337 (10%)

Query: 7   AIIGLGPAGSALARKLAGKMQ-VIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTL 65
            IIG GPAG A A  LA   + V+ L++    G     KPC G +   +    +   L L
Sbjct: 9   IIIGAGPAGLACATALAAAGREVLVLERLSTAG----PKPCAGGVPAGSLEPDMPPEL-L 63

Query: 66  PVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLCRK 125
                    + + +                  INR     WM+    A+  V       +
Sbjct: 64  ERSFHRQRIVTACQDFQFQGE-----DPIIHTINRERLGSWMQQRAEAAGAVIQTG--TR 116

Query: 126 IWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEKH 185
             R + +          +  I+ +YLVGADG+NS+VRRHL     +     I   +    
Sbjct: 117 ALRINGRTL-----TTDQGEISFQYLVGADGSNSLVRRHLGLPLVL---AGIGITYQVPG 168

Query: 186 PVPFYSCIF-DNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKT 244
             P            + Y+W          G     +  + R   L +++  +  + G  
Sbjct: 169 HFPEMEWHLQPRLFGSGYAWIFPHRDSASVGVYAFRR--RQRSHLLHDRLHLWAEKRGLR 226

Query: 245 V---KSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLL 301
           +   +     V F  R   F     + FL G+AAG  S  + EGI+ AL S   + + +L
Sbjct: 227 LDQARPRASLVSFDYRGSRF----GSLFLAGDAAGLASGLTGEGIAAALYSGRAVAATIL 282

Query: 302 KQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALR 338
           K   +        +   R +   ++V+      PA R
Sbjct: 283 KDHGQAPDLAPLLS---RHRQHSRLVRLTTALPPAGR 316


>UniRef50_C7LZD6 Geranylgeranyl reductase n=1 Tax=Acidimicrobium ferrooxidans DSM
           10331 RepID=C7LZD6_ACIFD
          Length = 429

 Score =  133 bits (334), Expect = 1e-29,   Method: Composition-based stats.
 Identities = 73/363 (20%), Positives = 128/363 (35%), Gaps = 24/363 (6%)

Query: 6   VAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
             ++G GPAGS  AR+LA    +V  +D+     T    K CG ++ P A  +    GLT
Sbjct: 7   CVVVGAGPAGSIAARQLALAGWRVTLVDRS----TFPRDKACGDVVGPQALATLAAVGLT 62

Query: 65  LPVDVIANPQIFSVK---TVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDS 121
              +      +        + + AS    +      + R  FD W++    A+       
Sbjct: 63  PEPEWPRIGDLDVWVEGARLHLPASPGLAHPGEGRMVTRRLFDAWLRDAAVAAGARAIVG 122

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIR--KYVAIQQ 179
             R + +  D   V       +  + A  +VGADGA S V R +      R     A+++
Sbjct: 123 RVRGLVQGADGVRVHL----DDGVLDADAVVGADGALSTVARSVGAASPTRALWGFALRR 178

Query: 180 WFAEKHPVPFYSCIFDNSIT-NCYSWSISK-DGYFIFGGAYPMKDGQTRFTTLKEKMSAF 237
           + A          +   +     Y W+    DG    G    +   + R   L+  +  +
Sbjct: 179 YVASSTLDADRVDLLAQASGFASYGWAFRGADGIANVGVGIAVGGERARLRGLRPLLDDY 238

Query: 238 QFQFGKTVKSEKCTVL--FPSRWQDFVCGKDNAFLIGEAAGFISASSLEGI-SYALDSTD 294
             + G    ++   +              +    L+G+AAGF++    EGI +       
Sbjct: 239 LGRIGLVDVADAPVLGGWLRMGGIGVAPWRGRVLLVGDAAGFVNPLQGEGIWAALASGAQ 298

Query: 295 ILRSVLLKQPEKLNTAY--WRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSG---VAHI 349
              ++  + P     AY  W   +         ++    L  P L    + +G   +AH 
Sbjct: 299 AAAALGARGPLGGGPAYGRWAEAQMAPFLAGAALLHRAALWNPRLADRAVAAGARVLAHR 358

Query: 350 PQL 352
           P L
Sbjct: 359 PSL 361


>UniRef50_Q58915 Uncharacterized protein MJ1520 n=11 Tax=Methanococcales
           RepID=Y1520_METJA
          Length = 387

 Score =  133 bits (334), Expect = 1e-29,   Method: Composition-based stats.
 Identities = 59/337 (17%), Positives = 113/337 (33%), Gaps = 22/337 (6%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
             +DV IIG GP G      +    +V+ +++    G       C GL++ +  +     
Sbjct: 4   NDYDVVIIGGGPVGCITGEYI-KNGRVLIVEEHQSIG---VPLQCAGLISKNGVKELGNP 59

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDS 121
                V+ +    I+S K   V      N         R   D  +        +    +
Sbjct: 60  KG--VVNKVRGAYIYS-KNSMVK---IGNEGIRAYIFERKVMDKDIAIRAAKKCDFLLKA 113

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWF 181
              KI ++ + + V     G +  +  + +VGADGA ++  + L   +   + +     F
Sbjct: 114 YG-KIEKDKNGYKVEITHLGEKITLNPKIIVGADGAKTITGKKLGLVNNKNREILSSCQF 172

Query: 182 AEKHPV---PFYSCIFDNSIT-NCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAF 237
              +      F     D   +   ++W I      +  G     +   +      +    
Sbjct: 173 EMVNAEVDDDFVYIFLDRKYSERFFTWIIPMGKDRVRVGLIDRGNCYNKLIRFINENKIA 232

Query: 238 QFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILR 297
           +        +E  T   P  + D    KDN  L+G+AA  +   S  G+ +      I  
Sbjct: 233 KEILKNATITEFSTGSLPIGYLDKTF-KDNVLLVGDAACHVKPLSGGGLYFGAMGGKIAG 291

Query: 298 SVLLK------QPEKLNTAYWRATRKLRLKLFGKIVK 328
            V+ K      +  +L    W+ T    +K   ++ K
Sbjct: 292 EVISKYLNEDIENLELYDKRWKETFGSEIKNGLRVRK 328


>UniRef50_A4X7I8 Geranylgeranyl reductase n=25 Tax=Actinomycetales
           RepID=A4X7I8_SALTO
          Length = 375

 Score =  133 bits (334), Expect = 1e-29,   Method: Composition-based stats.
 Identities = 57/289 (19%), Positives = 98/289 (33%), Gaps = 16/289 (5%)

Query: 9   IGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVD 68
           +G GPAG + A   A       + ++         K CGG L   +  +          D
Sbjct: 2   VGAGPAGLSAAYVAARAGLATLVLERA---VHPRYKTCGGGLIGTSLAALADRIEVPAHD 58

Query: 69  VIANPQIFSVKTVDVAASLTRNYQRSYI--NINRHAFDLWMKSLIPASVEVYHDSLCRKI 126
                      T+D   + TR      +   + R  FD  +++   A+       +  + 
Sbjct: 59  RADRV----TFTLDGRRAFTRRSAAGPLVTMVRRDEFDDRLRAAAVAAGAELRQRVAVRA 114

Query: 127 WREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEKHP 186
              +     +  ADG    +TAR ++GADG++ +  RH+   H+        +       
Sbjct: 115 AEPEPDRVRLRLADG--ATVTARAVIGADGSSGVTARHVGVRHRQVDLGLEVELPVSPVQ 172

Query: 187 VPFY---SCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGK 243
              +     +    +   Y+W   KD     G       G+     L+  +        +
Sbjct: 173 RSRWRGRVLVDWGPLPGSYAWVFPKDDLLTVGVIAARGAGERTRAYLRSFVDRLGLTGVE 232

Query: 244 TVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDS 292
            V       L   R +     +    + G+AAG +   S EGISYAL S
Sbjct: 233 PVHDSG--HLTRCRQEGSPLRRGRVLVAGDAAGLLEPWSREGISYALRS 279


>UniRef50_O26821 Conserved protein n=1 Tax=Methanothermobacter thermautotrophicus
           str. Delta H RepID=O26821_METTH
          Length = 375

 Score =  132 bits (331), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 66/327 (20%), Positives = 115/327 (35%), Gaps = 31/327 (9%)

Query: 1   MEHFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M  +DV I+G GPAGS LAR  A    +V   ++K   G       C GL++       +
Sbjct: 1   MTDYDVLIMGAGPAGSTLARLTATKGFRVGLFERKKIIG---LPLQCAGLVSHRIMEVNV 57

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRS-YININRHAFDLWMKSLI-PASVEV 117
                LP + I N    +V        L  +  R     I+R A+D  +  L   A  E+
Sbjct: 58  -----LPDEFILNSVRGAVLHSPSGIKLRVSKDRPEAHVIDRTAYDQHLAELAMEAGAEL 112

Query: 118 YHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAI 177
              +  R    +     V          ++A  LV A G ++   R+    + +R   + 
Sbjct: 113 TKGTAVRDFNEKTGHVRV------NGDELSADVLVDARGQSAAPSRYPARQYLVRFRDSE 166

Query: 178 QQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAF 237
                      F     D+ ++  + W I  D      G +     Q       +   + 
Sbjct: 167 MD-------TDFVDLKVDSRLSPGFMWRIPIDEQTARVGVF---GPQQNLKEFLKGFISD 216

Query: 238 QFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILR 297
                + ++S    +  P    D    +    L+G+AAG +  ++  GI  A  +  +  
Sbjct: 217 LSSDFEILESHHGFIPRP--DLDLRLVRGRCILLGDAAGQVKPTTGGGIVLASRAAGVAA 274

Query: 298 SVLLK--QPEKLNTAYWRATRKLRLKL 322
            V+    + +     Y  A RK+ +  
Sbjct: 275 EVIQGVLEGDADLKEYEDACRKIHMSE 301


>UniRef50_C9N331 Geranylgeranyl reductase n=3 Tax=Streptomyces RepID=C9N331_9ACTO
          Length = 440

 Score =  131 bits (330), Expect = 3e-29,   Method: Composition-based stats.
 Identities = 64/366 (17%), Positives = 122/366 (33%), Gaps = 45/366 (12%)

Query: 20  RKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSV 78
             LA     V+ L+K    GT    K CG  L P   +  +R G+ +        +    
Sbjct: 30  LHLARAGVDVLLLEK----GTFPRDKVCGDGLTPRGVQQLVRMGVDIDAPGWMRTKGMRW 85

Query: 79  ----KTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVYHDSLCRKIWREDDKW 133
               + V +    + ++    +  +RH FD  + +  + A   +  ++       +    
Sbjct: 86  VCGGRQVHIDWPRSGSHPDFGLTRSRHDFDDILARHAVAAGARLCLETRATGPLTDRAGR 145

Query: 134 HV----IFRADGWEQHITARYLVGADGANSM--VRRHLYPDHQIRKYVAIQQWFAEKHPV 187
            V    +  AD   +   A  ++ ADGA++   +   L  D       A ++++  +   
Sbjct: 146 IVGVSAVTGADKQPRTYRAPVVIAADGASARTALAMGLERDRGKPMATAARRYYRSEART 205

Query: 188 --------PFYSCIFDNSITNCYSWSIS-KDGYFIFG-GAYPMK-----DGQTRFTTLKE 232
                       C         Y W     DG    G GA P +     D +        
Sbjct: 206 HDPYLELWADLRCSRTGRDLPGYGWIFPLGDGRVNVGLGALPHRGHGTVDLRATMDRWMA 265

Query: 233 KMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDS 292
           +M A      +  +S   +   P  +           L+G++ G +S  S EGI  A+++
Sbjct: 266 RMPAHWELREENAESPLRSAALPMGFNRRPQYGRGLLLVGDSGGMVSPWSGEGIVQAMEA 325

Query: 293 TDILRSVL---LKQPEKLNTA-----YWRATRKLRLKLFGK------IVKSRCLTAPALR 338
            ++    +   L +PE          Y     +   + +        +V +R    P L 
Sbjct: 326 GEVAAETVALALHRPEGPGREQALHQYASEVNRRWGRYYRLGNTVADLVFARYGYRPLLN 385

Query: 339 KWIMRS 344
           + +M S
Sbjct: 386 RRVMAS 391


>UniRef50_B1L7J1 Dehydrogenase (Flavoprotein) n=1 Tax=Candidatus Korarchaeum
           cryptofilum OPF8 RepID=B1L7J1_KORCO
          Length = 383

 Score =  131 bits (330), Expect = 3e-29,   Method: Composition-based stats.
 Identities = 67/358 (18%), Positives = 129/358 (36%), Gaps = 28/358 (7%)

Query: 4   FDVAIIGLGPAGSALARKL-AGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +D AIIG GPAGSA +  L     +VI +++  +  +      CG  +   +      + 
Sbjct: 3   YDAAIIGAGPAGSAASFFLSQRGYKVIVIERSRKASS-----ICGEYVPDPSSLGIEGEV 57

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYIN--INRHAF-DLWMKSLIPASVEVYH 119
            +   +      +  ++ +       R+++  Y+   I R    +  ++       +V  
Sbjct: 58  GSSYSEFFKPFVVNELRRISFKI-FGRSFKVDYLGYSIKRSEMVEDRLERAQDLGADVRL 116

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDH----QIRKYV 175
                 + RE+     +++    +    ARY++GADG  S + R L  +      +    
Sbjct: 117 GESFITLEREE-----VYKILTSKGEYFARYVIGADGFLSRISRFLNGEKVDLDDVSIAF 171

Query: 176 AIQQWFAEKHPVPFYSCIFDNSITNCYSWSIS-KDGYFIFGGAYPMKDGQTRFTTLKEKM 234
            I+     + P        +      Y+W I   D     G                + M
Sbjct: 172 PIEAELKVEDPSEMKLIFDEEVAPGAYAWIIPRGDSRANVGLGI---RCSMITMNPLDYM 228

Query: 235 SAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTD 294
             F    G   +  +     P         +D  FL+G+AAG +  S+  GI  A+ S  
Sbjct: 229 RKFLSILGIEARDLRGR-FVPVGGLVKRVAEDGIFLLGDAAGMVIPSNGGGIHNAIISAY 287

Query: 295 ILRSVLLKQ-PEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAHIPQ 351
           +L   L  + PE+  T+Y     +  L+      ++       LR  I++  +  +P+
Sbjct: 288 LLSKSLESELPEEKYTSYVNRYIRGDLEAGLTYRRAA---DVLLRLGILKKMIGLLPR 342


>UniRef50_B4CWA5 Monooxygenase FAD-binding n=1 Tax=Chthoniobacter flavus Ellin428
           RepID=B4CWA5_9BACT
          Length = 433

 Score =  131 bits (329), Expect = 4e-29,   Method: Composition-based stats.
 Identities = 59/356 (16%), Positives = 113/356 (31%), Gaps = 34/356 (9%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
           E +DVAIIG GPAGS  A  LA   + + + ++ +          G  L P +   F R 
Sbjct: 3   EIYDVAIIGGGPAGSTAACLLARAGRRVVVLEREKFPRFHI----GESLLPYSMPVFDRL 58

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSY--------ININRHAFDLWMKS-LIP 112
           G+   +D  A P+  +        S    + R            + R  FD  +      
Sbjct: 59  GIREELDRTAQPKHGAELITACGTSHVIFHFRDGFRLAHHRSYQVERAGFDKLLLDNAAK 118

Query: 113 ASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDH--- 169
           +  E+  +   + +  +DD   V          +  RY++ A G ++++           
Sbjct: 119 SGAEIREEVAVQGVDFDDDGATVRLAGPDAP-TLRTRYVIDASGRHTVIGAQQGLKKSYA 177

Query: 170 QIRKYVAIQQWFAEKHPVPFYSCIFDNSI--TNCYSWSISKDGYFIFGGAYPMKDGQTRF 227
            + K+     +   + P     C     +   + + W I         G         ++
Sbjct: 178 HLNKFAVFAHYENVRRPPGEDGCTLTRMVRARDRWFWVIPLSDTKTSIGMVTDTTNFKQW 237

Query: 228 TTLKEKMSAFQFQ--------FGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFIS 279
               E      F+             +           ++          L G+AAGFI 
Sbjct: 238 KMSPEDALELGFREQPHFTDILASAKRVTPVYTTGDYSYRSTRLVGPRWMLAGDAAGFID 297

Query: 280 ASSLEGISYALDSTDILRSVLLKQPEKLNTA------YWRATRKLRLKLFGKIVKS 329
                G+  A+ S +     +    ++          Y +   ++ + L+ + V S
Sbjct: 298 PVFSTGVFLAIASGEQAADAIHISLDRPGKRAGLFAVYEKRLNRV-MDLYLRFVNS 352


>UniRef50_A0M1U0 Oxidoreductase n=2 Tax=Flavobacteriaceae RepID=A0M1U0_GRAFK
          Length = 377

 Score =  130 bits (327), Expect = 7e-29,   Method: Composition-based stats.
 Identities = 67/374 (17%), Positives = 138/374 (36%), Gaps = 34/374 (9%)

Query: 1   MEHFDVAIIGLGPAGSALARKL-AGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M++  V IIG G AG   A  L   ++ VI ++K+         K CG  L+ +      
Sbjct: 1   MKNTQVIIIGGGLAGLTAAIHLCQKEIDVILIEKEQ----YPHHKVCGEYLSREVIPYLN 56

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTR-NYQRSYININRHAFDLWMKSLIPASVEVY 118
              L +  + +  P I  V+   V+  L   +     I I+R++ D  +      S    
Sbjct: 57  SLNLNI--EALKAPIINRVEYSSVSGKLISCDLNMGGIGISRYSLDHLLYKKAENSGCTI 114

Query: 119 HDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDH--QIRKYVA 176
            +SL  +I   ++++ V        + IT+ +++GA G  S + + L      +   ++A
Sbjct: 115 INSLAVEIEYTNEQFIVT---TSQGEIITSEFVLGAYGKRSNLDKKLSRKFIQEQSGWLA 171

Query: 177 IQQWFAEKHPVPFYSCIFDNSITNCY-SWSISKDGYFIFGGAYPMKDGQ--TRFTTLKEK 233
           ++  +         + +  ++ +  Y   S ++               +        KEK
Sbjct: 172 VKAHYKTNSEFYSENLVSLHNFSGGYCGLSKTELNTINVCYLASYASFKNYKNTEDYKEK 231

Query: 234 MSA---FQFQFGKTVKSEKCTVLFPSR--WQDFVCGKDNAFLIGEAAGFISASSLEGISY 288
           +        +F    +      L  ++  +      +++  +IG++AG I      G++ 
Sbjct: 232 VLMKNPHLRKFFNNAEMVFDKELSIAQVCFDKKSMIENHILMIGDSAGLIHPLCGNGMAM 291

Query: 289 ALDSTDILRSVLLK-------QPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKW- 340
           A+ S  I    +L+           +   Y +   +   K   ++   R L    L K  
Sbjct: 292 AIHSAKIASEGILRFYNLKNITRNDVENNYVQEWNQ---KFSSRLKAGRVLQKVFLNKTL 348

Query: 341 --IMRSGVAHIPQL 352
             I +  +  +PQL
Sbjct: 349 TNISQGFLNRVPQL 362


>UniRef50_C5CID7 FAD dependent oxidoreductase n=1 Tax=Kosmotoga olearia TBF 19.5.1
           RepID=C5CID7_KOSOT
          Length = 377

 Score =  130 bits (327), Expect = 7e-29,   Method: Composition-based stats.
 Identities = 62/308 (20%), Positives = 107/308 (34%), Gaps = 25/308 (8%)

Query: 5   DVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           +V IIG GPAGS  A  LA +   I L  K Q       K CGG+L   + +   +    
Sbjct: 6   EVIIIGAGPAGSTAATVLARRNFDILLIDKCQ---FPRDKVCGGVLTAKSMKLLEKIHPG 62

Query: 65  LPVDVIANPQIFSVKTVDVAASLTRNYQRSYI-------NINRHAFDLWMKSLIPASVEV 117
           +   +   P   +  +     +  +N   +YI          R   D  +      +   
Sbjct: 63  VVFSLNLKPI--TKVSFGYPGTERKNESITYIYKKPLFYVATRKELDNALMENALRNGAK 120

Query: 118 YHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAI 177
           Y +    +I R DD + +     G     +A Y+V A G        L    +I   +A 
Sbjct: 121 YENDAIIRIERLDDGF-ICHGRSG--NTYSAPYVVIAAGVFGH--NLLENTSKISYSIAY 175

Query: 178 QQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFG-GAYPMKDGQTRFTTLKEKMSA 236
           +   A            D      Y+W +   G+F  G G+Y           + +K+  
Sbjct: 176 KAQTASVPITTATINFHDF----GYTWILPGKGFFNVGIGSYDNSLTYADAENIVKKLFN 231

Query: 237 FQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDIL 296
           F                      + V G      +G++ GF+   + EGIS+A+++    
Sbjct: 232 FPIGKLNAAPLPMFDKTISVDLNNMVPG---CLFVGDSGGFVDPWTGEGISFAMETGFCS 288

Query: 297 RSVLLKQP 304
              ++++ 
Sbjct: 289 AKAIIEKG 296


>UniRef50_A6GD06 Geranylgeranyl reductase n=1 Tax=Plesiocystis pacifica SIR-1
           RepID=A6GD06_9DELT
          Length = 407

 Score =  129 bits (325), Expect = 1e-28,   Method: Composition-based stats.
 Identities = 62/312 (19%), Positives = 104/312 (33%), Gaps = 25/312 (8%)

Query: 25  KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTVDVA 84
            + V  LDK          KPC G L      +       +   V  +  +         
Sbjct: 29  GLSVRLLDKHE----FPRPKPCAGGLTMRTVSALRYSITPVIERVADDWMLGLGMNEATR 84

Query: 85  ASLTRNYQRSYININ-RHAFDLWMKSL--IPASVEVYHDSLCRKIWREDDKWHVIFRAD- 140
                      + +  R   D +        A V    +   R++ R   +      A+ 
Sbjct: 85  MGAWPAKPMPIVAMTVRSRLDAYCLEQTKAAAGVTFERNGKVRELARLGSEGGSEGGANE 144

Query: 141 -----GWEQHITARYLVGADGANSMVRRHLYP----DHQIRKYVAIQQWFAEKHPVPFYS 191
                  + H TARY +GADGAN +  + L        +     A++       P+ F  
Sbjct: 145 GWSLRTEDAHYTARYFIGADGANGVSAKLLGRAAGHHARDSFAAAVEAEVPIDDPLRFAM 204

Query: 192 CIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAF-QFQFGKTVKSEKC 250
            +  + +   Y+W   K  +   G        +     LK  +  F + +  +T+++   
Sbjct: 205 EMRLDYVPRGYAWIFPKGDHLNVGIYA-----RGSVKGLKASLVEFVRARLDQTLETRDI 259

Query: 251 TV-LFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKLNT 309
                P   QD     D AFL+G+A G       EGI YA+ S       +  + E   +
Sbjct: 260 VGWRVPVSGQDRAPRTDGAFLVGDAGGLAEPMFGEGIFYAIASGQAAAQTIA-EVEAGRS 318

Query: 310 AYWRATRKLRLK 321
           A   A+R  RL+
Sbjct: 319 AAAMASRFARLR 330


>UniRef50_B8FIZ7 Geranylgeranyl reductase n=1 Tax=Desulfatibacillum alkenivorans
           AK-01 RepID=B8FIZ7_DESAA
          Length = 395

 Score =  129 bits (324), Expect = 1e-28,   Method: Composition-based stats.
 Identities = 60/321 (18%), Positives = 107/321 (33%), Gaps = 19/321 (5%)

Query: 24  GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTVDV 83
              +V+ L++          K C G + P       R  + L    + N  I    T   
Sbjct: 25  AGEEVLVLERSKTPN----FKTCAGGITPRGATLAARLNINLGP--LVNLYIMENNTPPW 78

Query: 84  AASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLCRKIWREDDKWHVIFRADGWE 143
             +            +R   D  +             +  +K+     K+ +  + D  +
Sbjct: 79  HYNRFEADIPVMGVADRQVIDQSVFLQAREEGVPIEHAAVKKLDHSRGKFLI--KTDNGD 136

Query: 144 QHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEKHPVPFYSCIFDN-SITNCY 202
              + R L+GADGANS+VRR            AI +    +        IFD  S+   Y
Sbjct: 137 --FSCRILIGADGANSLVRRSFGVKTPYYARAAIYRCIETEKYADR--IIFDGGSVPGGY 192

Query: 203 SWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAF-QFQFGKTVKSEKCTVLFPSRWQDF 261
            W        +  G Y +  G+     +KE + A+ + +FG T    +            
Sbjct: 193 GWIFPTGPGTVNAGVYDI--GKNFGGKIKEGLDAYIKDRFGLTSPPGQARGGVIPWGGHT 250

Query: 262 VCGKDN-AFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQPE--KLNTAYWRATRKL 318
                    L+G+A GF    + EGI  A+ +  I    ++K  +   +   ++R    +
Sbjct: 251 RPANGMPLLLVGDAGGFADPLTGEGIYQAIYTARIAARAVIKSRDHKTVRRRFYRTLLPM 310

Query: 319 RLKLFGKIVKSRCLTAPALRK 339
           R+ + G          P   +
Sbjct: 311 RVNVKGTEWFCPLAHTPFGAR 331


>UniRef50_Q1AWH0 Geranylgeranyl reductase n=1 Tax=Rubrobacter xylanophilus DSM 9941
           RepID=Q1AWH0_RUBXD
          Length = 420

 Score =  129 bits (323), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 61/317 (19%), Positives = 101/317 (31%), Gaps = 31/317 (9%)

Query: 2   EHFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           E +D+ ++G GP GS+ A   A   ++ + LD++    +    KPCG  L P A      
Sbjct: 3   ERYDLIVVGAGPGGSSTAYHAARSGLKTLLLDRQ----SFPRDKPCGDGLMPHAAAELAL 58

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNY-------QRSYININRHAFDLWMKSLIPA 113
            GL   ++   +   F+  T+    ++ R          R Y+   +            A
Sbjct: 59  MGLGGWLE-EEHHGAFTGFTIYSETAVLRQKVPPTLHGPRGYVARRKETDARLAGRAAEA 117

Query: 114 SVEVYHDSLCRKIWREDDKW--HVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQI 171
             E+   +   ++ R        V     G      A  +V ADG               
Sbjct: 118 GAELMEQTRAARLLRSAAGTVSGVEAERSGERVRFAAPLVVVADGVGGFAA---GGMKAR 174

Query: 172 RKYVAIQQWFAEKHPVPFYSCIFD-----NSITNCYSWSIS-KDGYFIFGGAYPMKDGQT 225
           +  VA +Q+F                   NS    Y W     DG    G     +  + 
Sbjct: 175 QNAVARRQYFRGVSGPEREHLQIFITPDMNSHHAGYGWVFHFGDGTANVGAGVSTRALER 234

Query: 226 RFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCG-------KDNAFLIGEAAGFI 278
               LK+    F  +     +        P +      G            L+G+A   +
Sbjct: 235 SGRNLKDFYDRFLEEPRVREQLAGAEPEGPPKSWSLKMGMWGARRYAQGTMLVGDAGSMV 294

Query: 279 SASSLEGISYALDSTDI 295
              S EG+ YAL+S  +
Sbjct: 295 HPISGEGVGYALESGRL 311


>UniRef50_A9G8G6 Monooxygenase family protein n=1 Tax=Sorangium cellulosum 'So ce
           56' RepID=A9G8G6_SORC5
          Length = 416

 Score =  128 bits (322), Expect = 3e-28,   Method: Composition-based stats.
 Identities = 74/364 (20%), Positives = 126/364 (34%), Gaps = 43/364 (11%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKM-----QVIALDKKHQCGTEGFSKPCGGLLAPDAQ 55
           M   +V I+G GPAG + A  LA        +++ L+K+         K C G L   A 
Sbjct: 1   MAAHEVVIVGGGPAGVSTALFLAHHRPALADRIVVLEKE----RYPRDKSCAGGLGERAD 56

Query: 56  RSFIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPA-S 114
           R+    G+T+ V  +    I +       A    N  R    + R  FD  +     A  
Sbjct: 57  RALSSIGVTIDVPSVVVHGISAAFQAGEVALREGNIGRV---VRRAEFDRALALAARARG 113

Query: 115 VEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKY 174
           V +   +        +D   V    +        R +VGADG  S+VRR +       + 
Sbjct: 114 VRIVEGARVTGAALSEDGARV----ESSAGVFDGRVVVGADGVGSVVRRAMGLPFGKLRA 169

Query: 175 VAIQ---QWFAEKHPVPFYSCIFDNSITNCYSWSISK---DGYFIFGGAYPMKDGQTRFT 228
            A++   +  A             +     Y W           +  GAY + +G     
Sbjct: 170 QAVEVDTEPVAGDRARDLLHFEMRDRSFAGYLWDFPTLVDGRELVCRGAYVLHEGALGVA 229

Query: 229 --------TLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISA 280
                    L+ ++ A      +  +            +  V  +  A L+GEAAG I  
Sbjct: 230 RPAPDAERVLRSRLEALGLDPDRYRRKRFAERGL---DRRAVIARPAALLVGEAAG-IDP 285

Query: 281 SSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKW 340
              EGI+ A+    +    L ++ E  +  +    R++   L G  ++         R+ 
Sbjct: 286 MLGEGIAQAIAYGALAGEYLAEKLEARDLGFHDWGRRVDRSLLGLDLR--------FRRR 337

Query: 341 IMRS 344
           +MR+
Sbjct: 338 VMRA 341


>UniRef50_A7BBW6 Putative uncharacterized protein n=1 Tax=Actinomyces odontolyticus
           ATCC 17982 RepID=A7BBW6_9ACTO
          Length = 422

 Score =  127 bits (320), Expect = 4e-28,   Method: Composition-based stats.
 Identities = 52/346 (15%), Positives = 109/346 (31%), Gaps = 45/346 (13%)

Query: 16  SALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQ 74
           S+ A  LA   + V+ L+K          K CG  L P A    I  G    VD     +
Sbjct: 19  SSTAYHLARVGLDVVLLEKS----PFPRDKICGDGLTPAAVHELIAMG----VDTTGWMR 70

Query: 75  IFSVKTVDVAASLTRNYQR----SYININRHAFDL---WMKSLIPASVEVYHDSLCRKIW 127
              +  +    ++  ++          + R   DL     +  + A   +Y         
Sbjct: 71  NRGLTVIGGGHTVHMDWPDQKSLPGYGMTRARMDLDHTLARRAVEAGARLYEGVTVIGAI 130

Query: 128 REDDKWHVIFRADGWEQH------ITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWF 181
           ++     V  +             + A  +V A G  + +   L  + ++ + + +    
Sbjct: 131 QDGSGRVVGVQVKSGRGKNAATFEVRASIVVDAGGVAARLATSLGLEKKMNRPMGVAARA 190

Query: 182 AEKHPVPFYSCIFDN-----------SITNCYSWSIS-KDGYFIFG-GAYPMKDGQTRF- 227
               P      +  +            +   Y W     DG    G G+   + G T   
Sbjct: 191 YFHSPRGDEEWMESHLELWSGTPGASDLLPGYGWIFPMGDGIVNVGLGSVASRAGATNLP 250

Query: 228 --TTLKEKMSAFQFQFGKTVKSEKCTVL---FPSRWQDFVCGKDNAFLIGEAAGFISASS 282
                K   +    ++G T +++   +     P  +           L+G+A G +S  +
Sbjct: 251 YREVFKTWTANLPEEWGFTPENQIGQLRSAALPMSFNRKPHYTQGLVLVGDAGGMVSPYN 310

Query: 283 LEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVK 328
            EGI+ A+ +     S + +   + + A         +  +  +++
Sbjct: 311 GEGIAPAMKAGRYAASCIAQALSRSHRAGIDRA----MSEYPHMLR 352


>UniRef50_B9LNF2 Geranylgeranyl reductase n=11 Tax=Halobacteriaceae
           RepID=B9LNF2_HALLT
          Length = 369

 Score =  127 bits (318), Expect = 7e-28,   Method: Composition-based stats.
 Identities = 65/342 (19%), Positives = 110/342 (32%), Gaps = 23/342 (6%)

Query: 5   DVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           D  ++G GP GS  AR+ A   + + + +K   GT      C G ++      +      
Sbjct: 3   DFVVVGAGPPGSRFARRAAAAGRDVVVFEKGSIGT---PLACSGHVS---DDVWEYVPDD 56

Query: 65  LPVDVIANPQIFSVKTVDVAASLTRNYQRSYIN---INRHAFDLWMKS-LIPASVEVYHD 120
              +++ N    +   V    S    + +S      I+R   D  +      A  +V  +
Sbjct: 57  ARDELLQNRVYGARFHVGGPGSKAYPFYKSEPVSNVIDRVGLDRTLADCAREAGADVREN 116

Query: 121 SLCRKIWREDDKWHVIFRA-DGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQ 179
                +   DD+  V  R   G  + + AR + G DG  S VRR L           +  
Sbjct: 117 HTVVGVDERDDRVVVEVRTPAGDVETVEARMVAGCDGPTSRVRRSLGLPEPDELLHGVLA 176

Query: 180 WFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQF 239
           +                +    ++W I +                     +         
Sbjct: 177 FDEAPDDGDLVDVHL--TAPTFFAWRIPRGD-----AGVEYGLAAPPSDDVSAMFDRLTD 229

Query: 240 QFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSV 299
            +  T     C+   P    + V   D AFLIG+AA      +  GI Y + + D+   V
Sbjct: 230 AYDVT-TDHFCSGAIPVGPPERV-TTDRAFLIGDAAAQTKPFTGGGILYGMTAADVAAEV 287

Query: 300 LLKQPEKLNTAY---WRATRKLRLKLFGKIVKSRCLTAPALR 338
           +  +       Y   WR      ++L   I +   L  P  R
Sbjct: 288 IDPRDPATLADYESGWRDAIGTEIRLGSAIRRCYSLPEPVQR 329


>UniRef50_B5Y9L9 FAD binding domain, putative n=1 Tax=Coprothermobacter
           proteolyticus DSM 5265 RepID=B5Y9L9_COPPD
          Length = 370

 Score =  127 bits (318), Expect = 7e-28,   Method: Composition-based stats.
 Identities = 59/348 (16%), Positives = 122/348 (35%), Gaps = 24/348 (6%)

Query: 5   DVAIIGLGPAGSALARKL-AGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG- 62
           D+ I+G   +G  LA  +    ++ + +++K +  +     P  GL+ P   +   +   
Sbjct: 10  DLLIVGASFSGLTLAYSVHNPGLRSLIVERKRRLWS-----PSTGLITPPTLKLLEQVFP 64

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSL 122
             +P+           K V     L+      ++ +++ +F    +  +P+S  +     
Sbjct: 65  FGIPIIRAFTSMKVIFKDV-GEVLLSSREPFLFL-LDKDSFFSAAEEHLPSSFTLALGCS 122

Query: 123 CRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFA 182
             K   +  K    +     E  I    LVGADGA S V +              +   +
Sbjct: 123 FVKTENKTAKVQTHYT----ETTIRYDLLVGADGALSKVAKSSGLPLVKEWLYGYEWKIS 178

Query: 183 EKHPVPFYSCIFDNSITNCYS-WSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQF 241
                 F + + D +++  Y  W    +G    G A        R   ++  M  + F F
Sbjct: 179 RPAEDDFITFVVDPTVSRAYGIWMFPVNGGVRIGLASKKP---LRKIDVQSIMKQY-FSF 234

Query: 242 GKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLL 301
              +   K     P         K++  L+G+AAG       +GI  A+ S       + 
Sbjct: 235 DGPLLDYKGGA-IPISGPVRAPFKEDVILLGDAAGLCGPFLGDGIQTAVKSGIAAARAVE 293

Query: 302 KQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAHI 349
           +       +Y    +K  +    K +K + L      +++ ++ +  +
Sbjct: 294 QPNVGP--SYVELLKKTEVT---KYLKQQALLRSIWDRFVSKNTLKRL 336


>UniRef50_B5YDH3 FAD dependent oxidoreductase, putative n=2 Tax=Dictyoglomus
           RepID=B5YDH3_DICT6
          Length = 396

 Score =  127 bits (318), Expect = 7e-28,   Method: Composition-based stats.
 Identities = 64/346 (18%), Positives = 124/346 (35%), Gaps = 22/346 (6%)

Query: 4   FDVAIIGLGPAGSALARKLAGK--MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
           +D+ I+G GP GS     LAGK  ++ + +++  + G       C G L+  A   F   
Sbjct: 3   WDLVIVGGGPVGSFAGY-LAGKNNIKTLIIEEHSKIGE---PLHCLGKLSIHAFEEF--- 55

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRS-YININRHAFDLWMKSLIPASV-EVYH 119
              LP + I N              +     +     ++R  FD  M  L   +   +  
Sbjct: 56  --PLPKESIRNSLKGGYFFFPNGNFIKLKKSKPDSYILDRSLFDKNMAELAGKNGCTLLL 113

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQ 179
            +    I  E++   +I       + I A+ ++ A+GA     + L    +   Y+   Q
Sbjct: 114 SAKAIGIEIENEATRLIIEEKNRRRKIEAKVIINAEGAKRQFAKRLGL--KPNPYLVSLQ 171

Query: 180 WFAEKHPVPFYSCIF----DNSITNCYSWSISKDGYFIFGGAY-PMKDGQTRFTTLKEKM 234
           +      +    C+            + W          G A  P ++ +         +
Sbjct: 172 YEVIGLELLDKECVEVYLGSTYSKGFFLWVSPYGNLTKIGVAVQPNENPKIFLDKFLNNL 231

Query: 235 SAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTD 294
              +    + +KS    +     ++++     N  ++G+AAG+  +++  GI + L    
Sbjct: 232 KKTRNSGIEIIKSYGGIIPILGPYEEYYYP--NILIVGDAAGYNKSTTGGGIYFGLQGAQ 289

Query: 295 ILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKW 340
           I    + K  E  N  + +   KL  K FGK +K   +    L + 
Sbjct: 290 IAIEQVKKYLEDNNINHLKTFPKLTYKKFGKELKFTKIVRKFLNQL 335


>UniRef50_A3W734 Geranylgeranyl reductase n=4 Tax=Rhodobacteraceae
           RepID=A3W734_9RHOB
          Length = 386

 Score =  126 bits (317), Expect = 1e-27,   Method: Composition-based stats.
 Identities = 71/349 (20%), Positives = 126/349 (36%), Gaps = 26/349 (7%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M+ FDV ++G GPAG++ A       ++V  +D+K    +    K CGGL+   A+R + 
Sbjct: 1   MQRFDVIVVGAGPAGASAAYAATRAGLRVALIDRK----SFPREKLCGGLITGRARRHYA 56

Query: 60  RDGLT-LPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEV 117
                 +P +                  L ++    Y  + R   D  +    + A  + 
Sbjct: 57  EIFGHAMPFEPQDCKTTVDFWFRGRPMGLIKDAPALYTTM-RWDMDAMLCGQALGAGAQD 115

Query: 118 YHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHL--YPDHQIRKYV 175
           +      +I  + D   V+ +       +    L+GADG +S V R L   P  + R   
Sbjct: 116 FTGQAVAEI--DHDARTVMLK---GGAVLDYGVLIGADGVHSQVARALFGQPFDRQRIGF 170

Query: 176 AIQQWFAEKHPVPFYSCIFD-NSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKM 234
            ++         P      D  +    Y W   K      G    + +       +K  M
Sbjct: 171 GLEIEARGAPSDPAAPIRIDLAAAQWGYGWVFPKRCSTTVGVGGLLSEN----PDMKRAM 226

Query: 235 SAFQFQFGKTVKSEKCTVL-FPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDST 293
           + +    G   +         P      + G+    L+G+AAG +   + EGI YA+ S 
Sbjct: 227 ADYCAVLGLASEEASVKGQFLPFGDFRPIPGQGAVLLVGDAAGLVDPITGEGIGYAMQSG 286

Query: 294 D-----ILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPAL 337
                  + ++   +P+   + Y RA R +   L    +    +  PAL
Sbjct: 287 QLAAKAAIAALGAGRPQTALSHYRRALRPVHRALHMARLIRPVIFLPAL 335


>UniRef50_A5FDA0 FAD dependent oxidoreductase n=2 Tax=Bacteroidetes
           RepID=A5FDA0_FLAJ1
          Length = 375

 Score =  126 bits (317), Expect = 1e-27,   Method: Composition-based stats.
 Identities = 59/336 (17%), Positives = 122/336 (36%), Gaps = 32/336 (9%)

Query: 5   DVAIIGLGPAGSALARKLAGK-MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           DV IIG G AG   A  L+ K ++VI ++K +        K CG  ++ +        G 
Sbjct: 6   DVLIIGGGLAGLTAAIHLSQKNLKVILIEKSN----FPRHKVCGEYISNEILPYLTWLGA 61

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLC 123
            +  ++  +       T     +           I+R+A D ++     A+  +      
Sbjct: 62  DV-TELNPSSISKFEFTASNGKTAMVELPLGGFGISRYALDDFLYQKAIANHCLIIKENV 120

Query: 124 RKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPD--HQIRKYVAIQQWF 181
             +   DD + V        Q +TA+ ++GA G  S + + L     H+   ++A++  +
Sbjct: 121 IDVSFSDDLFTVT----SSNQILTAKIVLGAFGKRSNLDQALDRSFFHKKSPWLAVKAHY 176

Query: 182 AEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYP--------MKDGQTRFTTLKEK 233
           +  +       + +      Y   ++K    I    Y          K+ Q     +  K
Sbjct: 177 SG-NLEDDLVALHN--FKGGY-CGVAKVENNIINICYLADYATFKQYKNIQDYQEGVLYK 232

Query: 234 MSAFQFQFGKTVKSEKCTVLFP-SRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDS 292
               +  F  ++   +  +      ++     +++  +IG+ AG I      G++ A+ S
Sbjct: 233 NKHLKAVFENSMLLFEKPLTISQISFEKKKAVENHIIMIGDTAGLIHPLCGNGMAMAVHS 292

Query: 293 TDILRSVLLK-------QPEKLNTAYWRATRKLRLK 321
             I   ++L+         + L   Y +  +K   K
Sbjct: 293 AKIASELILEYYSDDKASRKVLEKKYTKEWKKHFGK 328


>UniRef50_C6QH96 Geranylgeranyl reductase n=2 Tax=Alphaproteobacteria
           RepID=C6QH96_9RHIZ
          Length = 361

 Score =  126 bits (316), Expect = 1e-27,   Method: Composition-based stats.
 Identities = 64/313 (20%), Positives = 110/313 (35%), Gaps = 24/313 (7%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M  FDV ++GLGPAG++ A+ +A     V+ALD+K   GT      C  L+     +   
Sbjct: 8   MNTFDVIVVGLGPAGASAAQAIAKGGASVLALDRKEAAGT---PVQCAELIP----QLIA 60

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVY 118
            +   +   +            D       N+    I  +R  FD  + +  I A     
Sbjct: 61  SEAGDVRRSLRQRVAEMLTFVEDEGGDRVPNFPGQMI--DRADFDAKLVEDAIAAGATCR 118

Query: 119 HDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQ 178
             ++ R I  +D    +    D     + +R ++ ADG  S+V R         ++   +
Sbjct: 119 FKTMVRAI--DDAGLMITSSKD----RLKSRVIIAADGPRSLVGRAAGF--SNTEFAETR 170

Query: 179 QWFAEKHPVPFYSCIF-DNSITNCYSWSISKDGYFIFG---GAYPMKDGQTRFTTLKEKM 234
           Q   +       + IF    I   Y W   KD     G    A      +   + L +K+
Sbjct: 171 QITVKLCGSYAATDIFLSAEIAGGYGWLFPKDDIANLGVGVAAGCKDRLKPLLSALHDKL 230

Query: 235 SAFQFQFGKTVKSEKCTVLFPSRWQDFV-CGKDNAFLIGEAAGFISASSLEGISYALDST 293
              +      +K     +            G     L G+AAG  +  +  GI+ A+ S 
Sbjct: 231 IEQKRVGRSVLKVTGGAIPVGGIQGPVGQLGSTPVLLAGDAAGLTNPITGAGINAAVISG 290

Query: 294 DILRSVLLKQPEK 306
            +     L+  + 
Sbjct: 291 ALAGEAALRFLDG 303


>UniRef50_B4X0T8 FAD dependent oxidoreductase, putative n=2 Tax=Alcanivorax
           RepID=B4X0T8_9GAMM
          Length = 362

 Score =  126 bits (316), Expect = 1e-27,   Method: Composition-based stats.
 Identities = 56/301 (18%), Positives = 98/301 (32%), Gaps = 21/301 (6%)

Query: 25  KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTVDVA 84
            ++V  + +    G     KPC G +    +++  R   ++   V       +V      
Sbjct: 26  GLRVAVISRPPSRG-----KPCAGGV---TEKAVARYRFSIAPVVREAVTSLAVSHSSSP 77

Query: 85  ASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSL-CRKIWREDDKWHVIFRADGWE 143
                +     +   R   D + +        V+H++     + +  D   +  R     
Sbjct: 78  VRHLSSATPFCVMTERAELDAFCRGQAEYQGAVFHETAGLTGLEQWADCVRIETR---EG 134

Query: 144 QHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEKHPVPFYSCIFD-NSITNCY 202
              +A +L+ ADGANS V R L   H     +AI+     +    +     D   I   Y
Sbjct: 135 AVFSAPWLIAADGANSAVARLLGERHP-AGAMAIEGCVPRESVRNYPPMTLDFGVIRGGY 193

Query: 203 SWSISKDGYFIFG-GAYPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDF 261
            W   K  +   G   +       + +TL+    A      K V          +     
Sbjct: 194 GWLFPKGDHVNVGLYVWRHGAAAPQRSTLQRYCQARLGAEAKHVAGYP----LGTWLPHT 249

Query: 262 VCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLK 321
                    +G+AAG       EGI  A+ S  +    +L   E+ +  Y RA    R +
Sbjct: 250 RLANGRVLFVGDAAGCTEVLLGEGIYGAVLSGQLAAQAILG--ERPDVFYPRALAGWREE 307

Query: 322 L 322
           L
Sbjct: 308 L 308


>UniRef50_Q1VX49 FAD dependent oxidoreductase, putative n=1 Tax=Psychroflexus
           torquis ATCC 700755 RepID=Q1VX49_9FLAO
          Length = 371

 Score =  126 bits (316), Expect = 1e-27,   Method: Composition-based stats.
 Identities = 68/360 (18%), Positives = 130/360 (36%), Gaps = 30/360 (8%)

Query: 1   MEHFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M  +DV IIG G AG   A  L+   +QV+ L+K+    T    K CG  ++ +      
Sbjct: 1   MNTYDVIIIGGGLAGLTSAIDLSKDGLQVLLLEKE----TYPKHKVCGEYVSNEISPYLN 56

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTR-NYQRSYININRHAFDLWMKSLIPASVEVY 118
           R G+    +     +I S++  D    L           I+R+AFD  +     A+   +
Sbjct: 57  RLGVN--FETTPPDEIHSLQLSDRKGQLVEIKLPLGGFGISRYAFDHLLFKKAKANGVDF 114

Query: 119 HDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDH--QIRKYVA 176
                  +   DD++ +        Q   +   +G+ G  S + + +      Q   ++ 
Sbjct: 115 VFETVTDVEFIDDRFTIKTAQ----QTFMSILAIGSFGKRSNLDKKMDRSFITQKTPWIG 170

Query: 177 IQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQT-------RFTT 229
           I+  +           + +         S ++ G   F         +            
Sbjct: 171 IKAHYTSSDFPEGSVQLHNFE-GGYCGLSKTETGAVNFCYLAHYDTFKKANSIEDFNHKI 229

Query: 230 LKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYA 289
           L +      F     +  EK   +    +Q+    + +  + G++AG I      G++ A
Sbjct: 230 LSQNPHLKSFLETSKMDFEKHLAISQVSFQNKKAVEHHMLMAGDSAGLIHPLCGNGMAMA 289

Query: 290 LDSTDILRSVLL-----KQPEKLNTAYWRATRKLRLK--LFGKIVKSRCLTAPALRKWIM 342
           + S  ++ + +      K  +KL   Y R  +K   K  +FG I + + L  P L ++ M
Sbjct: 290 IHSAKLVSNEIKSFFKHKNRDKLEANYSRIWKKTFQKRLIFGSIFQ-KILLQPQLTRYGM 348


>UniRef50_D2RGA8 Dehydrogenase (Flavoprotein)-like protein n=1 Tax=Archaeoglobus
           profundus DSM 5631 RepID=D2RGA8_ARCPR
          Length = 357

 Score =  126 bits (316), Expect = 1e-27,   Method: Composition-based stats.
 Identities = 61/323 (18%), Positives = 114/323 (35%), Gaps = 26/323 (8%)

Query: 6   VAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTL 65
           + I+G GPAGS  A  L     V  +++    G   F   C GL++    R   +     
Sbjct: 2   ILIVGGGPAGSLSAIAL-KNYDVTVVEEHSSAG---FPVQCAGLISERCYRELKKFSDCK 57

Query: 66  PVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLCRK 125
             D+          +V++   +        + + R   D  + +       V   +    
Sbjct: 58  VNDIRGAVFFSPNNSVELEGKV------GAVVVERKLLDRDLLAKASEYANVMIKTKFLG 111

Query: 126 IWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEKH 185
           + +       + R+ G +  +   Y++GADG  S V            Y A+Q     + 
Sbjct: 112 VEKG----KAVLRSMGKKIELDYDYIIGADGVYSTVSNVFNFKKP-EVYSALQITCRFEC 166

Query: 186 PVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKTV 245
                  I+    ++ + ++I  D +   G        Q     ++  +     +   +V
Sbjct: 167 ISDDLVEIYFG-FSDYFCYAIPFDEFAKIGVI----SSQNPMPVMRRLLRWLGKRVKGSV 221

Query: 246 KSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQPE 305
                    P    DFV  KD   LIG++AG +   +  G+ Y L + + L+       +
Sbjct: 222 LELNAGA-IPIGLVDFV--KDRVMLIGDSAGMVKPYTGGGLYYILKAVEKLKH--FPNLK 276

Query: 306 KLNTAYWRATRKLRLKLFGKIVK 328
           K+   Y +  R +  K+  KI K
Sbjct: 277 KVQKEYVKDLR-IEYKVGTKIAK 298


>UniRef50_C9RKL4 FAD dependent oxidoreductase n=1 Tax=Fibrobacter succinogenes
           subsp. succinogenes S85 RepID=C9RKL4_FIBSS
          Length = 398

 Score =  125 bits (314), Expect = 2e-27,   Method: Composition-based stats.
 Identities = 59/355 (16%), Positives = 107/355 (30%), Gaps = 26/355 (7%)

Query: 2   EHFDVAIIGLGPAGSALARKLA----GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRS 57
             + V I G GPAG   A +L     G  Q++ LDKK       F   C   ++      
Sbjct: 7   NSYKVVICGAGPAGLMAAYQLGKLTGGDGQILLLDKKEPWKEPIF---CAEAVSTHRLNE 63

Query: 58  FIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLI-PASVE 116
                 +     ++     S K            +     ++R  F   +      + VE
Sbjct: 64  LWPIDESWVRGSLSGIYFTSPKGYKAEF----YSKDCGRLLDRSKFHHAIADACVESGVE 119

Query: 117 VYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHL--------YPD 168
              D+L + I + ++ W++  +       ++A   + A G    + R +           
Sbjct: 120 CRFDALVKSIEKTENGWNLNVQVGKEFFSLSADAFIDASGPGCRLTRGIPCLEGIESGDT 179

Query: 169 HQIRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFT 228
                  A+ +    +H       ++ +     Y W   +DG  +  G    KD +    
Sbjct: 180 DLEPGIFAVAE--GIEHDRDHIDLLYGSEFPGGYGWIFPRDGKEVNVGFVLSKDAKPDMP 237

Query: 229 TLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISY 288
             ++        +           +      D    K   F  G+AA  ++  S  GI  
Sbjct: 238 LREKLKHFIATHYPNAKVKAIYGGMIACGQSDKPLAKCGLFKAGDAASCVNPLSRSGIVE 297

Query: 289 ALDSTDILRSV----LLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRK 339
           AL S  I+       L    +   +    +     +   GK         P L K
Sbjct: 298 ALLSGKIVAEAVHEWLNASDDAARSRIEASVLDRWMAKLGKSHLQIARAKPGLAK 352


>UniRef50_B8GUG5 Geranylgeranyl reductase n=5 Tax=Gammaproteobacteria
           RepID=B8GUG5_THISH
          Length = 363

 Score =  124 bits (312), Expect = 3e-27,   Method: Composition-based stats.
 Identities = 54/328 (16%), Positives = 110/328 (33%), Gaps = 26/328 (7%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           +   DV ++GLGP G++ AR  A   + V+A+++    G       C   +         
Sbjct: 8   IRSVDVLVVGLGPGGASAARTAAEAGLSVLAVERNKVLGE---PVQCAEFIPT------- 57

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVY 118
             G     + +   +I  +K++ + +      +   + INR  FD  + +       E++
Sbjct: 58  PMGGYAKAEKVLLQRITGMKSI-LPSGTVHESEFPGLMINRAEFDRAIAREAERLGAELW 116

Query: 119 HDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQ 178
             S    +  +     V  R +  E  +  + L+ ADG +S V   L  +  +   V  +
Sbjct: 117 TRSPLVALDADARIATV--RREDAEVKLRYKVLIAADGPHSPVAAQLGLEPLV--VVQTR 172

Query: 179 QW-FAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMK---DGQTRFTTLKEKM 234
           Q+      P         +     Y+W   K      G     +   + +     L  ++
Sbjct: 173 QYTVPLLKPYADTDIWLSDEYPGGYAWLFPKGELANLGLGADRRWEDNLKEPLDRLHRQL 232

Query: 235 SAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTD 294
                   + +      +  P           +   +G+AAG     +  GI+  + S +
Sbjct: 233 VEAGLLGEEILYRTGGAI--PVGGLREHLVVGDVLFVGDAAGLTHPITGAGIAAGVVSGE 290

Query: 295 I---LRSVLLKQPEKLNTAYWRATRKLR 319
           +     +  L+  E     Y    R   
Sbjct: 291 LAGKAAAAWLEGDEDAFEDYEEDVRDQF 318


>UniRef50_A6BZI3 Probable alkylhalidase n=1 Tax=Planctomyces maris DSM 8797
           RepID=A6BZI3_9PLAN
          Length = 430

 Score =  124 bits (312), Expect = 3e-27,   Method: Composition-based stats.
 Identities = 61/331 (18%), Positives = 111/331 (33%), Gaps = 31/331 (9%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
            +DV IIG GPAGS +A  LA + +   +  + +          G  L P+      R G
Sbjct: 15  EYDVVIIGAGPAGSTVAALLAEQGRNTLVVDRARFPRFHV----GESLIPETYWPLKRLG 70

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNY---------QRSYININRHAFDLWMKSLIPA 113
           L   +   A P+  SV+ V      T  +               + R  FD  +     +
Sbjct: 71  LIERLKQTAFPKKLSVQFVTDEGVETMPFYFHDYKDHESSQTWQVYRAEFDQMLIDNAQS 130

Query: 114 SVEVYH-DSLCRKIWREDDKWH-VIFRADGWE-QHITARYLVGADGANSMVRR--HLYPD 168
               +H ++    +  +D++   V  +    E ++ITAR +V A G +  +     L   
Sbjct: 131 KGATFHNEAQVTDLLTQDEQVTGVKVKLGNQETRNITARLVVDASGQSGFIANRLKLKQT 190

Query: 169 HQIRKYVAIQQWFAEKHPVP----FYSCIFDNSITNCYSWSIS-KDGYFIFGGAYPM--- 220
             + +   +   F      P      + I        + W I  +D     G    M   
Sbjct: 191 DPVLRKGTVWAHFKNAQRDPGIDEGATLILQTEGKRSWFWYIPLQDNVVSIGCTGDMNYM 250

Query: 221 -----KDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAA 275
                K+ +  F    E+    + +  +     +        +           L G+A 
Sbjct: 251 FSKERKNSEDIFFQEVERCIGIKRRLTEAHPVTEFMTTKDFSYHSSQPAGPGWMLAGDAL 310

Query: 276 GFISASSLEGISYALDSTDILRSVLLKQPEK 306
           GFI      G+  A+ S +++   + +  E 
Sbjct: 311 GFIDPVYSSGVFLAMKSGELIADAINEAYET 341


>UniRef50_D1BBC7 Geranylgeranyl reductase family protein n=11 Tax=Actinomycetales
           RepID=D1BBC7_SANKS
          Length = 431

 Score =  124 bits (312), Expect = 4e-27,   Method: Composition-based stats.
 Identities = 51/314 (16%), Positives = 103/314 (32%), Gaps = 39/314 (12%)

Query: 25  KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL-----TLPVDVIANPQIFSVK 79
            + VI ++K     +    K CG  L P A    +R G+        +  I    +   +
Sbjct: 31  GLDVILMEKS----SFPRDKICGDGLTPRAVGELVRMGVPTREEDGWIRNIGLRAVAGGR 86

Query: 80  TVDVAASLTRNYQRSYININRHAFDLWMKSLIPA-SVEVYHDSLCRKIWREDDKWHVIF- 137
           + +      R Y    +  +R   D  +     A   ++   +       ++    V+  
Sbjct: 87  SFEFPWPELRAYPSYGLARSRMNLDQTLAEHARASGAKLMERTNVTGPVVDERTGRVVGV 146

Query: 138 ---------RADGWEQHITARYLVGADGANSMVRRHLYPDHQIRK--YVAIQQWFAEKHP 186
                    R  G E    A  ++ ADG ++ +   L  +  + +   VA++ +F     
Sbjct: 147 TARPVDSNGRRAGEETTYRAPVVIAADGVSARMATSLGIEKAMNRPMGVAVRTYFTSPRH 206

Query: 187 VPFYSC----IFDNS-----ITNCYSWSIS-KDGYFIFGGAYPMKDGQTRFTTLKEKMSA 236
              +      ++D       +   Y W  +  DG    G               K   + 
Sbjct: 207 DDPWMESQLELWDGKPGESNLLPGYGWIFALGDGTVNVGLGSVSSTAAATKIDYKALFAR 266

Query: 237 FQFQF----GKTVKSEKCTVL---FPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYA 289
           +        G T +++   V     P  +           L+G++ G +S  + EGI+YA
Sbjct: 267 WMENTPEEWGFTPENQIGPVRGAALPMAFNRKPLYTRGLMLVGDSGGMVSPFNGEGIAYA 326

Query: 290 LDSTDILRSVLLKQ 303
           L +  +   V+ + 
Sbjct: 327 LQAGRVAADVVSQA 340


>UniRef50_C5CCQ4 Geranylgeranyl reductase family protein n=5 Tax=Micrococcaceae
           RepID=C5CCQ4_MICLC
          Length = 466

 Score =  124 bits (311), Expect = 5e-27,   Method: Composition-based stats.
 Identities = 81/405 (20%), Positives = 137/405 (33%), Gaps = 60/405 (14%)

Query: 5   DVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           DV I G GPAG+  A  LA     V+ L+K          K CG  L P A R     G+
Sbjct: 21  DVLISGCGPAGATAAAHLAAAGLDVVVLEKTAH----PREKVCGDGLTPQAVRELQLLGV 76

Query: 64  ---TLPVD-----VIANPQIFSV-KTVDVAASLTRNYQRSYININRHAFDLWMKSLIPA- 113
                P D     VI   ++ +  ++VDV  + TR +    +   R  FD  +  L  + 
Sbjct: 77  PHRGEPGDDGGWRVIRGLRLRAGERSVDVPWAPTRTWPDYALTRTRRDFDALLAELARSR 136

Query: 114 SVEVYHDSLCRKIWREDDKWHVIF---------RADGWEQHITARYLVGADGANSM--VR 162
             EV        + +++    V           R  G     TA  ++  DG ++   V 
Sbjct: 137 GAEVRERHAVTGVVQDEAGRVVGLDAELIAPNGRKTGQTARFTAPIVLACDGVSARAAVS 196

Query: 163 RHLYPDHQIRKYVAIQQWFAEKHPVPFYSCIFDNSIT-----------------NCYSWS 205
             L+        VA++ ++                                     Y W 
Sbjct: 197 AGLHRREDRPMGVAVRAYYTAGAAADGAIPAPPGDRGEWMESWLRLPDAEGNPLPGYGWL 256

Query: 206 IS-KDGYFIFGGAY----PMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVL---FPSR 257
               DG    G       P          LK    A    +G   ++     L    P  
Sbjct: 257 FPLADGTVNVGLGILDTSPQFGKLDYRGLLKSWTGALTADWGIAEQTRTSRTLGAALPMA 316

Query: 258 WQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQ--------PEKLNT 309
           +           L+G+AAG +S  + EGI +A+++  +   + ++          + + +
Sbjct: 317 FNRTPQHVPGMLLVGDAAGMVSPFNGEGIGFAMEAARLAADLAVQAHAAGTDGAADAILS 376

Query: 310 AYWRATRKLRLKLFGKIVK-SRCLTAPALRKWIMRSGVAHIPQLK 353
            Y   T+ L  + F    + +R +  P + +  + +GVA  P L+
Sbjct: 377 RYPVITQHLWGRHFALGARFARLIGDPRVMRAALGAGVAAPPLLR 421


>UniRef50_B8ES76 Monooxygenase FAD-binding n=1 Tax=Methylocella silvestris BL2
           RepID=B8ES76_METSB
          Length = 392

 Score =  124 bits (311), Expect = 5e-27,   Method: Composition-based stats.
 Identities = 61/345 (17%), Positives = 103/345 (29%), Gaps = 33/345 (9%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
            +D  +IG GPAG + A  LAG  + +A+ ++         K CG  ++        R G
Sbjct: 2   SYDAIVIGAGPAGCSAALALAGMGRRVAIVEQS---RFPRKKVCGEYMSAVNLDLLDRLG 58

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRS-----YININRHAFDL-WMKSLIPASVE 116
               V   A P +  V       ++     R+        + R   D   +++   A   
Sbjct: 59  AGASVRARAGPSVRRVALFASGPAVEAGMPRAPGDAFGCALGRDVLDSVLLQAATDAGAA 118

Query: 117 VYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADG--ANSMVRRHLYPDHQIRKY 174
           V+       +        V   + G  + +TA  ++ A G  A   +   L   ++ + +
Sbjct: 119 VFQPWRAVDVCAGGAAAAVRIESAGESRVLTADAVIAAHGSWARGPLASQLERKNRRQDF 178

Query: 175 VAIQQWFAEKHPVPFYSCIFDNSITNCYS---WSISK----------DGYFIFGGAYPMK 221
              +  F           +        Y    W+             D        Y   
Sbjct: 179 FGFKAHFRGASLARDLMPLL--VFPGGYGGMVWADQGRLSLSCCLRRDALARVRDLYRAP 236

Query: 222 DGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISAS 281
             Q  F  ++    A +   G            P R     C   + F +G  AG     
Sbjct: 237 AAQAVFAHIRASCPAARIALGGAALDGAWLAAGPIRPGVRACYAADIFRVGNIAGECHPI 296

Query: 282 SLEGISYALDSTDILRSVLLKQP-------EKLNTAYWRATRKLR 319
             EGI+ AL S  +L   L +               Y  A R+  
Sbjct: 297 IAEGIAMALQSGWLLACALARHDVWDARSRAAAGRDYSEAWRRQF 341


>UniRef50_C8VZJ8 Electron-transferring-flavoproteindehydrogenase n=1
           Tax=Desulfotomaculum acetoxidans DSM 771
           RepID=C8VZJ8_DESAS
          Length = 434

 Score =  123 bits (308), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 57/332 (17%), Positives = 108/332 (32%), Gaps = 46/332 (13%)

Query: 1   MEHFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M+ FD  ++G GPAG+  A  LA   M+V+ L++    G    +K   G       R   
Sbjct: 1   MKQFDAIVVGGGPAGTTAALVLARAGMRVVVLER----GEYPGAKNVSGAALYGT-RLLE 55

Query: 60  RDGLTLPVD----------VIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKS 109
           R      +D          V+      ++ ++D  +        +   + R  FD W+  
Sbjct: 56  RLHPGFWLDAPIERYITRKVLGFMSEHALTSIDFKSENMGLPPYNAFTVIRPKFDRWLAL 115

Query: 110 LIPASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDH 169
               +  +           +++      R    +  + A  ++ ADG NS + R      
Sbjct: 116 KAEEAGALIISGTVVDGLIKENGVIKGVRTRRDKGELYADIVIAADGVNSFLAREAGLQR 175

Query: 170 QIRK--------------YVAIQQWFAEKHPVPFYSCIFDNSITN---CYSWSISKDGYF 212
           +++                  I++ F +       +  F  S+T       +  + +   
Sbjct: 176 ELKANELSLGIKEIIALDRQTIEERF-QLSGNEGVTHEFVGSVTGEATGGGFLYTNEDSL 234

Query: 213 IFGGAYPMKDGQTR-------FTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFV-CG 264
             G    +                LK   S      G   K     ++    W+ F    
Sbjct: 235 SIGVIMQVSSMLENRIRPYELLEKLKSHPSVRPLVRGGLAKEYSAHMIPEGGWKMFPKLF 294

Query: 265 KDNAFLIGEAAGFISASSL---EGISYALDST 293
                + G+AAG + A +    +GI+YA+ S 
Sbjct: 295 APGLLVAGDAAGMVLA-TGYYLQGINYAMISG 325


>UniRef50_Q01YQ3 Geranylgeranyl reductase n=1 Tax=Candidatus Solibacter usitatus
           Ellin6076 RepID=Q01YQ3_SOLUE
          Length = 390

 Score =  122 bits (307), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 56/333 (16%), Positives = 109/333 (32%), Gaps = 22/333 (6%)

Query: 21  KLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT-LPVDVIANPQIFSVK 79
             +  + VI +D+K       + KPCGG L   A   +        P  ++    + + K
Sbjct: 20  LASAGLGVILMDEKL-----AWEKPCGGGLTHKAYSQYPFLIENSTPKRLVTETVLAAPK 74

Query: 80  TVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLCRKIWREDDKWHVIFRA 139
               A  +T       +  +R   +  +      +      +   ++ R+   W +   A
Sbjct: 75  ----AGEVTLQLGDPLLIYSRLDLNRMLLERAERAGAQIEKTRVMEMNRKGSGWQLRTAA 130

Query: 140 DGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEKHPVPFYSCIFDNSIT 199
              +    A + + A GA + +R             A+  +            + D    
Sbjct: 131 GNLD----ADFCIVATGARNPLRDVGTQLTPPDTMAALGYYVQGDQARIDIQFLPD---L 183

Query: 200 NCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ-FGKTVKSEKCTVLFPSRW 258
             Y W   + G+   G     +   +    L+  M+       G    S     L    W
Sbjct: 184 EGYIWIFPRCGHLSIGICGKGEPASSLRKRLEAYMAGRGINWKGAAFYSHLLPSLDTKSW 243

Query: 259 QDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKL 318
           +      +    +G+AAG +   + EG+ YA+ S D+    LL   +          R+L
Sbjct: 244 KQNRVSGEGWMAVGDAAGLVDPITGEGLYYAIRSADLAAQSLL--ADAGQEENALQYRRL 301

Query: 319 RLKLFGKIVKSRCLTAPALRKWIMRSGVAHIPQ 351
             + F   +     +  A R ++ R  +  +PQ
Sbjct: 302 LRRDFAADL--EFGSRLAKRVFMGRFMLGTVPQ 332


>UniRef50_Q2NEQ6 Predicted dehydrogenase n=1 Tax=Methanosphaera stadtmanae DSM 3091
           RepID=Q2NEQ6_METST
          Length = 386

 Score =  122 bits (306), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 58/322 (18%), Positives = 116/322 (36%), Gaps = 24/322 (7%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M ++D+ ++G GP GS  A K+A     V   D K++ G       C GL++ +     I
Sbjct: 1   MTNYDIIVVGGGPIGSTYAYKMAKLGYDVALFDMKNRIGQ---PLQCAGLVSTN-----I 52

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASL-TRNYQRSYININRHAFDLWMKSLI-PASVEV 117
            D   LP + I+N    +        ++           ++R  +D ++      A V+ 
Sbjct: 53  DDTKNLPREFISNEVRGANLISPNKTTIHVEKDNTVAYVLDRVLYDKYLFDRAINAGVDA 112

Query: 118 YHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAI 177
           +  ++   +   +    +     G   H  A+ +  A G NS   + + P+     ++AI
Sbjct: 113 HIGTMVDDVDINNTTLRI-----GNAYH-RAKLIAVACGPNSKTSKKMNPNLDEDSFMAI 166

Query: 178 QQWFAEKHP-VPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSA 236
           Q      +P   F        +   + W I         G +           L  ++S 
Sbjct: 167 QYTIQTDNPSTEFVDVSVREELLPGFLWKIPVSSNQSRIGLFTKNSYGGATKLLDNELSL 226

Query: 237 FQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDIL 296
                      +K   + P    +    ++N  L+G+ A  +  ++  GI    + T+I 
Sbjct: 227 ------NDEIIQKHYGIIPRFNINKKIVQNNTILLGDTASQVKPTTGGGIISGFNCTEIA 280

Query: 297 RSVLLKQPEKLNTAYWRATRKL 318
           ++   K  E  + +Y     + 
Sbjct: 281 KNNSNKMLESGDNSYLENYERE 302


>UniRef50_B1XX19 Monooxygenase FAD-binding n=3 Tax=Burkholderiales
           RepID=B1XX19_LEPCP
          Length = 425

 Score =  122 bits (306), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 68/318 (21%), Positives = 108/318 (33%), Gaps = 25/318 (7%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
             +V ++G GPAGSA A  LA     + L  +H        K CG  L PDA  +  R G
Sbjct: 25  DCEVLVVGAGPAGSACATWLARAGVDVVLVDQH---DFPRDKVCGDGLIPDAHAALARLG 81

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSL 122
           + L   +     I  V+ V           R  + + R   D  +     A     H  +
Sbjct: 82  V-LDAVMAQAQPIGHVRCVAPRGGQVDVAGRLAV-LPRRILDHLLVRHAQAGGARLHTPV 139

Query: 123 CRKIWREDD----KWHVIFRADGWEQHITARYLVGADGAN--SMVRRHLYPDHQIRKYVA 176
             +   ED        +          + A ++V A GA   +M+   L  + +    VA
Sbjct: 140 KFEGLIEDGGRVRGARLRQAGADTIHELRAGWVVLATGAAMPAMLGAGLC-ERRAPSGVA 198

Query: 177 IQQWFAEKHPVPFYS---CIFDNSITNCYSWSIS--KDGYFIFGGAYPMKDGQTRFTTLK 231
           ++            +    ++  +++  Y W      D Y I  G++  +D  T    L+
Sbjct: 199 LRAHVRNPALAGRQTTMDVVWHRALSPGYGWIFPCGGDVYNIGVGSFFKRDASTDAANLR 258

Query: 232 EKMSAF--------QFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSL 283
           +   AF            G    SE               G+      GEA G     + 
Sbjct: 259 DMFDAFTRVHAPAQALMQGGEWVSELKGAPLRCTLAGARTGRPGLLATGEAIGSTYDFTG 318

Query: 284 EGISYALDSTDILRSVLL 301
           EGI  AL++  +    LL
Sbjct: 319 EGIGKALETGLMAAEALL 336


>UniRef50_Q24QW7 Putative uncharacterized protein n=1 Tax=Desulfitobacterium
           hafniense Y51 RepID=Q24QW7_DESHY
          Length = 430

 Score =  122 bits (306), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 61/338 (18%), Positives = 107/338 (31%), Gaps = 41/338 (12%)

Query: 2   EHFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
             FDV I+G GPAGS+ A   A   ++V+ +++    G +  +   GG+L        I 
Sbjct: 3   NKFDVIIVGAGPAGSSAAIMAAQAGLKVLVIERGEYVGAKNMT---GGMLLSQVLNEVIP 59

Query: 61  DG-----LTLPVDVIANPQIFSVK--TVDVAASLTRNYQRSYININRHAFDLWMKSLIPA 113
           +      L  PV           +  TVD+          +  ++ RH FD W+      
Sbjct: 60  EFWKEAPLQRPVVSQRIMMTSGGRSLTVDIGNRKFSEPPFNGFSVLRHEFDAWLADKARE 119

Query: 114 SVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRK 173
           +  V                 V  +    E  +    ++ ADG NS++ R        + 
Sbjct: 120 AGAVLVTGTVVDDVIHAGNRIVGVKTRRDEGDVYGDIVILADGVNSLLARKAGLRKPYQA 179

Query: 174 YVAIQQWFAEKHPVPFYSCIFDNSITNC----------YSWSISKDGYF------IFGGA 217
           +  I     E   +P  +      +T            ++  I   G+       I  G 
Sbjct: 180 H-DIGLGVKELLDLPAKTINERFGLTGNNGAALMAIGDFARGIPGGGFLYTNKESISLGM 238

Query: 218 YPMKDGQTR--------FTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQD--FVCGKDN 267
                                K      +   G  +       L P    +       D 
Sbjct: 239 VLQPQALIDQKLTPDEVLERFKAVPEVARLLEGAKLIEYSA-HLIPEGGYNSMPKLWADG 297

Query: 268 AFLIGEAAGFI--SASSLEGISYALDSTDILRSVLLKQ 303
             + G+AAGF+  +  +L+G++ A+ S        +K 
Sbjct: 298 ILVAGDAAGFVVNTGITLQGMNLAIASGKCAGEAAVKA 335


>UniRef50_C8SW54 Monooxygenase FAD-binding n=1 Tax=Mesorhizobium opportunistum
           WSM2075 RepID=C8SW54_9RHIZ
          Length = 413

 Score =  122 bits (305), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 70/396 (17%), Positives = 111/396 (28%), Gaps = 50/396 (12%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           +   D  +IG GPAG++ A  LA     +A+ +K         K CG  ++        R
Sbjct: 4   LSTHDAIVIGAGPAGTSAALTLARHGWSVAIVEKS---AFPRRKVCGEYISASNLVLLDR 60

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYIN---------INRHAFDLWMKSLI 111
             +       A P+I  V        +      +            + R   D  +    
Sbjct: 61  LEIGDAWRADAGPEIRRVGFFSGETCVEAPMPDAKYGPAKDGFGRALGRDILDALLLQAA 120

Query: 112 -PASVEVYHDSLCRKIWREDDKWHVIFRADGWEQ-----HITARYLVGADGA--NSMVRR 163
             A  +++       I R+ D   V  +A G         + A  ++ A G+     +  
Sbjct: 121 RSAGAQIFQPCRAVAIDRDGDMQRVRIQARGENSGDETTTLRAPVIIAAHGSWEPGSLPS 180

Query: 164 HLYPDHQIRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSIS---------------- 207
            L   +     +  +  F      P    +   +    Y   +                 
Sbjct: 181 QLEKINHPSDLLGFKAHFTGSTLAPDLMPLL--AFPGGYGGMVLADHGRLSISCCIRREM 238

Query: 208 ------KDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDF 261
                 K G    G A P+      F  L                  +     P R    
Sbjct: 239 LARLRGKHGSGHDGVASPVSAADVVFHHLMASCRGVSDALDGACLDGRWLAAGPIRPGIR 298

Query: 262 VCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQP------EKLNTAYWRAT 315
            C + + F +G AAG       EGIS AL S  +L   L   P      E     Y  A 
Sbjct: 299 ACYERDIFRVGNAAGESHPIIAEGISMALQSGWLLARELSGAPSGRAGREAAGRRYQAAW 358

Query: 316 RKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAHIPQ 351
           R L             +        +M + V + PQ
Sbjct: 359 RGLFSTRVHAAAAIARIALGPGGPLLMAAAVRNFPQ 394


>UniRef50_D1JEF0 Putative uncharacterized protein n=1 Tax=uncultured archaeon
           RepID=D1JEF0_9ARCH
          Length = 412

 Score =  121 bits (304), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 57/351 (16%), Positives = 109/351 (31%), Gaps = 32/351 (9%)

Query: 2   EHFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           ++FDV I G GPAG + A   A  K   + ++     G         G    +A + F  
Sbjct: 3   KNFDVIIAGGGPAGLSAAIIAARNKCDTLLVESSKAFGYPIHD---SGATFSEAIKDF-- 57

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRS-YININRHAFDLWMKS-LIPASVEVY 118
               L   VI N              ++          + R   +  +        VE+ 
Sbjct: 58  ---NLSKGVITNRIDGVTIVSPKGYVVSTKLGEGIGYILERRELNRELAKIAANEGVEIK 114

Query: 119 HDSLCRKIWREDD---KWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPD---HQIR 172
                      +             G      ++ ++ A G N+++ + +        IR
Sbjct: 115 MPVKAVSPILSNGFVAGLQTKELIGGDNIEYKSKLVIDATGVNAVIAKAVGIHPGMSNIR 174

Query: 173 KYVAIQ-QWFAEKHPVPFYSCIFDNS--ITNCYSWSISK-DGYFIFGGAYPMKDGQT--R 226
             +  + +    +   P +  ++  S    + Y W   K DG    G        +    
Sbjct: 175 WAIGAEYEMTNVELDNPNFIELYFGSQIAPSGYGWIFPKGDGVANVGVGITHISNERINP 234

Query: 227 FTTLKEKMSAFQFQFGKTVKSEKCT---VLFPSRWQDFVCGKDNAFLIGEAAGFISASSL 283
           F  L   +  +     K   ++       + P          D   ++G+AA  +S    
Sbjct: 235 FKYLSRFIKEYPVTSKKLKNAQPLEYHVGILPIGPMFDQIVSDGLMIVGDAACQVSPHLG 294

Query: 284 EGISYALDSTDILRSVLLKQPEKLNTA------YWRATRKLRLKLFGKIVK 328
           EGI + + + +I   V +    K NT+      Y +  +K     +  + K
Sbjct: 295 EGIRFVMKAGEIAGEVAVDAINKNNTSKNNLTQYEKQVKKEIYPNYRLLYK 345


>UniRef50_C0VR61 Geranylgeranyl reductase n=2 Tax=Corynebacterium glucuronolyticum
           RepID=C0VR61_9CORY
          Length = 385

 Score =  121 bits (304), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 71/347 (20%), Positives = 116/347 (33%), Gaps = 30/347 (8%)

Query: 1   MEHF-DVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           ME F +VAIIG GPAGSA A  L  K  V+ +D           K CG  L P A R   
Sbjct: 4   MEFFPEVAIIGAGPAGSAAAIHLQDK-DVLLID----SAEFPRDKTCGDGLTPRAMRELS 58

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYH 119
             G+ LP            +T ++              + R  FD  + +  PA      
Sbjct: 59  ALGIDLPFRTRGLKLHGFGRTAEIPWEWG-----VGSAMRRQEFDALLYNRAPAQKLT-- 111

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYP--DHQIRKYVAI 177
             +      E+ +   + R    E  +  + ++ ADG  S     L      Q    +A 
Sbjct: 112 -GVATSPVVENGR---VVRFQVGEHVVHPQVVLVADGVRSTFGTQLGRVWHKQQVYGIAA 167

Query: 178 QQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAF 237
           + +         +       +   Y W          G        +      K+ +  +
Sbjct: 168 RSYCTSPRSSEPWIHSHFGDLP-GYGWFFPLVDAANVGCGALSTAARPAKVNTKKLLRFY 226

Query: 238 ----QFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDST 293
               Q +FG    +   +   P           N  L+G++A  ++  + EGI YAL++ 
Sbjct: 227 ASSIQEEFGLGEPTSVTSAALPMGGSVSGVSGRNWALLGDSACCVNPLNGEGIDYALETA 286

Query: 294 DILRSVLLKQ----PEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPA 336
            +  S++ +     P  L   Y   T  L   L  K++    +    
Sbjct: 287 RLAASLIDEDLRVWPSVLREHYGE-TFTLARSL-AKLLTYPRMLPTF 331


>UniRef50_UPI0001787E07 monooxygenase FAD-binding protein n=1 Tax=Geobacillus sp. Y412MC10
           RepID=UPI0001787E07
          Length = 383

 Score =  121 bits (303), Expect = 4e-26,   Method: Composition-based stats.
 Identities = 62/315 (19%), Positives = 117/315 (37%), Gaps = 35/315 (11%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
           +  DV +IG G AG++ A +LA +     L  +         K CG  ++P+ +      
Sbjct: 3   KQADVMVIGAGVAGTSCALQLAKQGHRTILLDRQS---FPRHKTCGEFMSPETREMLEYL 59

Query: 62  GLTLPV-DVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVYH 119
           G+ L V +V       +   +     +T         I+R+  D  + +S + A  E+  
Sbjct: 60  GVHLQVQEVNPAAMDHASIVMPHGGVITAPLPGKATGISRYELDRLLHESAVSAGAEIVT 119

Query: 120 DSLCRKI-WREDDKWHVIFRADGWEQHITARYLVGADG---ANSMVRRHLYPDHQIRKYV 175
            S   +I  R D ++ +  R    +    AR ++GA G      +     Y D  +  YV
Sbjct: 120 GSAVTEIRKRGDHRYEIETRQGNEQIRYEARAVIGAYGTKKPRGVASAETYRDDTV--YV 177

Query: 176 AIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMS 235
            ++  FA    VP    ++          S  ++G         +K  Q    ++ E + 
Sbjct: 178 GVKSHFAGIT-VPSRVELYFCE-GGYVGISPVENGKVNVAALLTLKSVQGSGKSVPEILK 235

Query: 236 A---------FQFQFGKTVKSEKCTV------LFPSRWQDFVCGKDNAFLIGEAAGFISA 280
           A          +   G+ V+  + ++      + P  W  +         IG+A   +  
Sbjct: 236 AASRSNNRLTERLAEGEPVEGTQVSIAPLRLSVRPEPWSQYPH-------IGDAMLMLPP 288

Query: 281 SSLEGISYALDSTDI 295
              +G+S AL S+ +
Sbjct: 289 LCGDGMSVALRSSLL 303


>UniRef50_C7M2T6 Geranylgeranyl reductase n=1 Tax=Acidimicrobium ferrooxidans DSM
           10331 RepID=C7M2T6_ACIFD
          Length = 436

 Score =  121 bits (302), Expect = 5e-26,   Method: Composition-based stats.
 Identities = 66/354 (18%), Positives = 118/354 (33%), Gaps = 42/354 (11%)

Query: 16  SALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT--LPVDVIAN 72
           ++ A  LA   + V+ L++K         K CG  L P +       GL   L       
Sbjct: 23  ASCAHWLAMRGIDVVVLERKQ----FPRDKVCGDGLTPRSVVQLEALGLGAELEARFHRY 78

Query: 73  PQIFSV---KTVDVAASLTRNYQRSYININRHAFDLWMK-SLIPASVEVYHDSLCRKIWR 128
             + +V   +T+D+                R   D  +  +       V       ++ R
Sbjct: 79  EGLRAVAFGRTLDIPWPNHPLLPSYGFVARRRELDALVVGAAADRGATVLFGHEGIELER 138

Query: 129 EDDKWHVIFRA---DGWEQHITARYLVGADGANSMVRRHLY--PDHQIRKYVAIQQW-FA 182
             +    +      DG    + AR++V A+G+N+ + R L    D      +AI+ +  +
Sbjct: 139 RGNGISAVLARRTNDGAVVRVRARWVVLAEGSNARLARSLGAIRDTSQPLGLAIRTYLPS 198

Query: 183 EKHPVPFYSCIFD-----NSITNCYSWSIS-KDGYFIFGGAYPMKDGQTR----FTTLKE 232
            +   P+     D       +   Y W     DG    G       G  R     T L  
Sbjct: 199 SRSDEPWIESALDVRDESGRVMPGYGWVFPMGDGSVNIGFGLLTNQGAWRHVNTTTELAR 258

Query: 233 KMSAFQFQFGKTVK----SEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISY 288
            +   + ++G  V+    ++      P           N  L+G+ A  I+  + EGISY
Sbjct: 259 FVDRVRDRWGLDVEHPLLAKPVGGKLPMGTTIKPVQGSNYLLVGDTAATINPFNGEGISY 318

Query: 289 ALDSTDILRSVLLKQ----PEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALR 338
           AL++  +  +++ +      +   T Y          L G       L    +R
Sbjct: 319 ALETGRLAATLIAEARRTDSDHPLTRYPAL-------LGGHYGTYYALGRRFVR 365


>UniRef50_O29239 Bacteriochlorophyll synthase, 43 kDa subunit (ChlP-2) n=1
           Tax=Archaeoglobus fulgidus RepID=O29239_ARCFU
          Length = 364

 Score =  120 bits (301), Expect = 6e-26,   Method: Composition-based stats.
 Identities = 58/322 (18%), Positives = 109/322 (33%), Gaps = 27/322 (8%)

Query: 5   DVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           D A++G GPAGS  A  L     V   ++    G   F   C GL++    + + +    
Sbjct: 2   DAAVVGGGPAGSLAAILLGKSYDVALFEEHQSAG---FPVQCAGLVS---DKCYKKLKEH 55

Query: 65  LPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLCR 124
              +      I        +  +    +   + + R   D  +        +V+     R
Sbjct: 56  CKAEKAIENHIKGAFFFSPSGKIVLEGRGEAVVVERKILDRLLFERAAERAKVFVKEKAR 115

Query: 125 KIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEK 184
                 + + +I       + ++A  ++GADG NS VR H      +  + A+Q     +
Sbjct: 116 L-----NGFRIIT----PSREVSAEKIIGADGVNSTVREHFGFP-TMGFFTAVQVEAKFE 165

Query: 185 HPVPFYSCIFDNSITN--CYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFG 242
                   ++     +   ++++I        G        +     +K   S      G
Sbjct: 166 PLDENCVELYFGGNWSDSFFAYAIPLGDTARIGVVSRSSPLRYLENLMKRHPSVSGRVEG 225

Query: 243 KTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLK 302
             V+     +  P R   F   K +  LIG+AAG +   +  G+ Y L    I    L +
Sbjct: 226 SAVELNAGAI--PDRLVKF--SKRDVALIGDAAGMVKPYTGGGLYYHL----IAAEKLAE 277

Query: 303 QPEKLNTAYWRATRKLRLKLFG 324
               L   Y ++  K   + + 
Sbjct: 278 SFPDL-KGYEKSYLKEMGREYR 298


>UniRef50_Q05TK1 Putative electron transfer oxidoreductase n=1 Tax=Synechococcus sp.
           RS9916 RepID=Q05TK1_9SYNE
          Length = 405

 Score =  120 bits (300), Expect = 9e-26,   Method: Composition-based stats.
 Identities = 76/370 (20%), Positives = 120/370 (32%), Gaps = 68/370 (18%)

Query: 6   VAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL- 63
           V I+GLGPAG+A    LAG  ++V+ALD+ H        K CG  L   AQ      GL 
Sbjct: 14  VLIVGLGPAGAACGMALAGSGLEVLALDRAH----FPRDKICGDALPLGAQTLVQHLGLL 69

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQRSYI--------------NINRHAFDLWMKS 109
           T   ++     +    +V           + ++               + RH  D W+  
Sbjct: 70  TTSPELQCRSSLEERGSVRARGYDQGLTGQGWLAERGAILSSTACLQTVRRHDLDHWLVE 129

Query: 110 LIPAS---VEVYHDSLCRKIWREDDKWHVIFRADGWEQH------ITARYLVGADGANSM 160
                   +E        +  +   +W V  R    E        IT   +VG DGA S 
Sbjct: 130 RCRERQLPMEFGWQVESLRWDQAIQRWQVRGRIRTREGKPLKRFAITTPVVVGCDGAASA 189

Query: 161 VRRHLYPDHQIRKYVAIQQWFAEKH----------PVPFYSCIFDNSITNCYSWSISKDG 210
           ++R   P           + +   H          P      ++    T  Y+W+ +  G
Sbjct: 190 IQRQSNPARPRSLQALASRCYLTPHESQTSSAQAQPRSRLHYLWPGEST--YAWAFAVPG 247

Query: 211 YFIFGGAYP---MKDGQTRFTTLKEKMSAF---------------QFQFGKTVKSEKCTV 252
            F  G A       D   R   L E+   +                     T+++    V
Sbjct: 248 GFNCGVAAMVNRHGDLPIRGRDLMERTRQWIQTLNHDWDHSAVEASHHNTSTIQTMAIPV 307

Query: 253 LFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLK------QPEK 306
           + P+             L G+AA  +      GI  AL+S  +  +V+ K       P  
Sbjct: 308 IHPTTAPQ---SSAGILLAGDAAALVDPHQGHGIDRALESGALAATVIRKGVAMGLAPAA 364

Query: 307 LNTAYWRATR 316
           L+  Y +   
Sbjct: 365 LSERYQQRLA 374


>UniRef50_C8SAI9 Geranylgeranyl reductase n=1 Tax=Ferroglobus placidus DSM 10642
           RepID=C8SAI9_FERPL
          Length = 377

 Score =  120 bits (300), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 64/318 (20%), Positives = 113/318 (35%), Gaps = 19/318 (5%)

Query: 6   VAIIGLGPAGSALARKLAGK-MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           V ++G   AGS  A  L  +  +V+  +   +    GF   C GL++ D        G+ 
Sbjct: 17  VCVVGGRVAGSLTALNLGERDAEVVVFE---EHRDSGFPVSCAGLISEDCYERLRNFGVN 73

Query: 65  LPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLCR 124
              + I     FS     V A          + + R   D  +        EV   S   
Sbjct: 74  AKQNEIKGAFFFSPSGKYVEAIGKSR----GVVVERKLMDSQLLRRASKVAEVRMSSKVV 129

Query: 125 KIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEK 184
            + R +    V F  +G E+  +   LVGADG NS+V +        + ++A+Q     +
Sbjct: 130 GVERGE----VTFIVNGREKKESFDVLVGADGVNSVVAKSFGFKRP-KIFLAVQILSEFE 184

Query: 185 HPVPFYSCIFDNSI--TNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFG 242
                +  ++         +++++  +      G     +       L  +  +   + G
Sbjct: 185 AIDEKFVELYFGRRYSEGFFAYAVPIEEDLAKIGVVSKTNPMVYLQRLINEHPSVSERIG 244

Query: 243 KTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLK 302
           K    E      P    DFV  ++N  LIG++AG +   +  GI Y L   ++L      
Sbjct: 245 KGF-LELNVGAIPIGLVDFV--RENVALIGDSAGMVKPYTGGGIYYTLIGAEVLGKTFPN 301

Query: 303 QPEKLNTAYWRATRKLRL 320
             +    AY +   K   
Sbjct: 302 -LKAFEKAYKKRMWKEYY 318


>UniRef50_A1KG38 Possible oxidoreductase n=11 Tax=Mycobacterium RepID=A1KG38_MYCBP
          Length = 408

 Score =  119 bits (299), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 51/325 (15%), Positives = 96/325 (29%), Gaps = 25/325 (7%)

Query: 27  QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTVDVAAS 86
            V+ +D      T    KPCG  L P A     + GL   +      +   +        
Sbjct: 31  DVLVID----TATFPRDKPCGDGLTPRAVAELHQLGLGKWLADHIRHRGLRMSGFGGEVE 86

Query: 87  L---TRNYQRSYININRHAFDLWMKSLIPA-SVEVYHDSLCRKIWREDDKWHVIFRADGW 142
           +     ++      + R   D  ++ +       +   +    +   D    V+      
Sbjct: 87  VDWPGPSFPSYGSAVARLELDDRIRKVAEDTGARMLLGAKAVAVHH-DSSRRVVSLTLAD 145

Query: 143 EQHITARYLVGADGANSMVRRHLYP--DHQIRKYVAIQQWFAEKHPVPFYSCIF------ 194
              +  R L+ ADGA S + R L      +    VA++ + +  +    +          
Sbjct: 146 GTEVGCRQLIVADGARSPLGRKLGRRWHRETVYGVAVRGYLSTAYSDDPWLTSHLELRSP 205

Query: 195 DNSITNCYSWSIS-KDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCT-- 251
           D ++   Y W     +G    G        +     L+  +S +                
Sbjct: 206 DGAVLPGYGWIFPLGNGEVNIGVGALSTSRRPADLALRPLISYYTDLRRDEWGFTGQPRA 265

Query: 252 ---VLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKLN 308
               L P           N  LIG+AA  ++  + EGI Y L++  +   +L      L 
Sbjct: 266 VSSALLPMGGAVSGVAGSNWMLIGDAAACVNPLNGEGIDYGLETGRLAAELL--DSRDLA 323

Query: 309 TAYWRATRKLRLKLFGKIVKSRCLT 333
             +         + F    +   L 
Sbjct: 324 RLWPSLLADRYGRGFSVARRLALLL 348


>UniRef50_C7PJY7 Geranylgeranyl reductase n=1 Tax=Chitinophaga pinensis DSM 2588
           RepID=C7PJY7_CHIPD
          Length = 415

 Score =  119 bits (298), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 59/363 (16%), Positives = 113/363 (31%), Gaps = 52/363 (14%)

Query: 21  KLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDV-IANPQIFSVK 79
                +  + +DK          K CG  L+     +  +    +   +  AN ++ S  
Sbjct: 22  LAQLGIHCVVVDK----AVFPRDKVCGDGLSGKVITALNKIDPAIATRLKEANFKVNSWG 77

Query: 80  TV---DVAASLTRNYQRSY-------------ININRHAFDLWMKS--LIPASVEVYHDS 121
                    SL   Y+  Y                 R  FD ++       + + +    
Sbjct: 78  VTFVSPGRHSLDVGYRPDYNSSNQQHKETPIGYVCKRMDFDNFLVDEVRRRSEITLLEGV 137

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHL-----YPDHQIRKYVA 176
              K   ++D ++V    D     + A  L+ A+GA+S   + +      P+H +    A
Sbjct: 138 TVDKYELKEDGYYVTGSND---FKVKADLLIIANGAHSSFTKEVANITMEPEHYVAGIRA 194

Query: 177 IQQWFAEKHPVPFYSCIFDNSITNCYSWSIS-KDGYFIFGGAYPMKDGQTRFTTLKEKMS 235
             +  +  +   F    F   +   Y W     +G    G     +  + +   LK+ M 
Sbjct: 195 YYKNVSGNNADNFIELHFLKDLLPGYFWIFPLPNGEANVGVGVLSEAVRKKKMNLKKSML 254

Query: 236 -------AFQFQFGKTVKSEKCTVL-FPSRWQDFVCGKDNAFLIGEAAGFISASSLEGIS 287
                   F+ +F              P   +  V   +   L+G+AA  I   + EGI 
Sbjct: 255 DIIANDPVFKERFKDAELVSSIDGYGLPLGSKQRVISGERYMLVGDAAYLIDPFTGEGIG 314

Query: 288 YALDSTDILRSVLLKQPEKLNTAYWR--ATRKLRLKLFG----------KIVKSRCLTAP 335
             L S  I      +  +  +T+  +         ++ G          K+VK   L   
Sbjct: 315 NGLYSGRIAALQAAEALKANDTSAAQLAKYDSEIYRILGPELKLSHRLQKLVKYPWLFNT 374

Query: 336 ALR 338
            ++
Sbjct: 375 LMK 377


>UniRef50_Q6KZ83 FixC protein n=1 Tax=Picrophilus torridus RepID=Q6KZ83_PICTO
          Length = 396

 Score =  119 bits (297), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 73/345 (21%), Positives = 129/345 (37%), Gaps = 31/345 (8%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           M  +D  ++G GPAGSA A KLA   +   + ++   G E  SK   G +          
Sbjct: 1   MLDYDAVVVGAGPAGSAAALKLASLGKKTLVLER---GPEPGSKNVSGAMIRKDF-VTSV 56

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIP-ASVEVYH 119
            G  LPV+        S+ + +   SL   Y  +     R  FD W+ S+   A   V  
Sbjct: 57  FGDGLPVERNVERMKVSLYSSERPVSL-EFYPENLATTGRLKFDKWLSSVSEKAGAIVIP 115

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQ- 178
            +    I  +D +   +    G    ++ R +V A+G NS++        +++   A+Q 
Sbjct: 116 KTTVTDIKWKDGRATGVVTDRGE---VSTRSIVLAEGVNSLLAISSGIKRELKPDQAVQT 172

Query: 179 -QWFAEKHPVPFYSCIFDNSITNCYSW-SISKDGYFIFGGAYPMKD------GQTRFTTL 230
            ++          S    +S     SW  I  D     G  Y  +D      G      +
Sbjct: 173 VKYVYSIKKEQINSMFNLSSDDAGLSWRIIRADPVLTAGFLYTYRDSVSVGVGAPISGLI 232

Query: 231 KEKMS------------AFQFQF-GKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGF 277
           ++K+              F+  F G +++     ++  + + D +  K N +L G+A G 
Sbjct: 233 EKKIKPEELMDMFMKYTGFEDLFKGFSLREYSAKIIPEAGFPDMLASKSNVYLCGDALGL 292

Query: 278 ISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKL 322
           +   + +GIS A++S  +          +    Y     K   K+
Sbjct: 293 VDPLTFDGISPAIESGLLAGEAAFSNMPEFEYRYSLIKDKEISKI 337


>UniRef50_C6A374 Geranylgeranyl hydrogenase n=9 Tax=Thermococcaceae
           RepID=C6A374_THESM
          Length = 375

 Score =  119 bits (297), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 66/328 (20%), Positives = 116/328 (35%), Gaps = 26/328 (7%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           +DVAIIG GP G+ LA  LA + +V+ L+ K+  G     K C G++  +       + L
Sbjct: 7   YDVAIIGGGPVGNYLANLLASEFKVVVLEAKNSFGG----KACTGIMGAE-----NYEKL 57

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVYHDSL 122
            LP + I N    +V    + +            ++R   +  + ++ I    E Y  + 
Sbjct: 58  NLPKEAIINKLRGAVFYSRIQSFEIERPTPQAYVVDRKLLERKLAENAIRHGAEYYMGAR 117

Query: 123 CRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQ-QWF 181
                        I +    +  I A + VGADG NS V + +            + +  
Sbjct: 118 FLGFK----NRKAIVQRFNEKFEIEADFYVGADGLNSKVAQEIGARTDAEFLSGYEVEVV 173

Query: 182 AEKHPVPFYSCIFDNSITN-CYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ 240
            + +   F     +  I N  + W    + +    G +   D   RF  LK        +
Sbjct: 174 GDFNRTDFVEIWVNKEINNEFFMWLAPINNFNARLGTFGTYDRLFRFLKLKLLKETNIVE 233

Query: 241 FGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVL 300
                                   K N  L+G+AA  I   +  GI Y +  +  LR  +
Sbjct: 234 IKAGNVGLGF---------RKPWVKGNIALVGDAALQIKPLTAGGIVYGMLCSHALRYSI 284

Query: 301 LKQPEKLNTAYWRATRKLRLKLFGKIVK 328
            +   K+     +  +K  +    +I +
Sbjct: 285 RRGNLKMYEDLCKDIKKQ-ISFGLRIRR 311


>UniRef50_Q7U5F1 Predicted dehydrogenase (COG0644) n=20 Tax=Cyanobacteria
           RepID=Q7U5F1_SYNPX
          Length = 381

 Score =  119 bits (297), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 54/300 (18%), Positives = 99/300 (33%), Gaps = 16/300 (5%)

Query: 26  MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTVDVAA 85
             V+ L++  +       KPCGG +A   Q+ F          VI            V A
Sbjct: 32  HNVLVLERDAK----PRIKPCGGGMAASVQQWFPFSLEPAVEQVIGRVDFSWCLEDPVVA 87

Query: 86  SLTRNYQRSYININRHAFDLWMK-SLIPASVEVYHDSLCRKIWREDDKWHVIFRADGWEQ 144
           +L  +    +  + R   D  +    I A  E         I R  D W V   +DG   
Sbjct: 88  NLPGDAP--FWIVRREKLDQLLVDQAIGAGAERLTGVEVVDICRSRDVWEVT-ASDGRRW 144

Query: 145 HITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW--FAEKHPVPFYSCIFDNSITNCY 202
              A+ +V ADG+NS   + L    +  +           + +     +      +   +
Sbjct: 145 Q--AKAVVIADGSNSPWPQRLGLGAKHPQLATTMSVRLEGQGNVADGSTRFEFGLVKQGF 202

Query: 203 SWSIS-KDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDF 261
           +W+    DG  I  G++  K        L + +    F     ++      ++    +  
Sbjct: 203 AWAFPIADGVNIGVGSFIGKQDADPDQVLAQLLPDLGFPADAGIRQRGKLRVWSGHHR-- 260

Query: 262 VCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLK 321
               +   ++G+AA        EG+  AL S       L +  +  +      +R +R +
Sbjct: 261 -LDGNGIVVVGDAASLCDPFLAEGLRPALMSGCEAARHLNQWLKGDSKDLQGYSRTMRKR 319


>UniRef50_D2LI13 Monooxygenase FAD-binding n=1 Tax=Rhodomicrobium vannielii ATCC
           17100 RepID=D2LI13_RHOVA
          Length = 387

 Score =  119 bits (297), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 70/355 (19%), Positives = 122/355 (34%), Gaps = 23/355 (6%)

Query: 4   FDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +D+ I G   AG   A+  A   ++V  L+ K   G    S    G+L  +A +      
Sbjct: 8   YDLVIAGASFAGLVAAKTAAIRGLKVAVLEPKAAAGQHVAS---TGILTKEAAQEIDLPY 64

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPA-SVEVYHDS 121
                         +++ VD+ A  +      ++  +      W+         ++   +
Sbjct: 65  NLTRRVYGVRLYAPNLRHVDLFAPDS-----FFVTTDTGRVLGWLAQEAQRVGAQILWRT 119

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWF 181
             +   R+D     IF   G    I+AR+++GADGA S V R        R  +A +  +
Sbjct: 120 PFQGAERKDG----IFLFKGVN--ISARHIIGADGAKSAVARAFGLGLNTRFMLATEHEY 173

Query: 182 AEKHPVP-FYSCIFDNSITNCY-SWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQF 239
                 P F  C  D+ +   + +W       F  G A      +        K +A  F
Sbjct: 174 DGLDADPRFLHCFLDSQLAPGHIAWVAPGPSLFHAGLAA-RPGRRPHLAAFLAK-TAPIF 231

Query: 240 QFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSV 299
            F      E+ T   P          D   LIG+AAG +S ++  G+ +A         V
Sbjct: 232 GFEDARLVERRTGRIPCGGLVRPFATDGVTLIGDAAGMVSPTTGGGVGFAFQYGRRAAQV 291

Query: 300 LLKQPEKLNTAYWRATRKLRLKL-FGKIVKSRCLTAPALRKWIMRSGVAHIPQLK 353
           +      L  +   A  K   +     + +     AP     ++ + +   P  K
Sbjct: 292 VADHLLHLGPSPEMALAKELPRFGLSHLTRLALNLAPP--NALLSAALGTAPMRK 344


>UniRef50_C0QF41 Putative dehydrogenase n=1 Tax=Desulfobacterium autotrophicum HRM2
           RepID=C0QF41_DESAH
          Length = 312

 Score =  119 bits (297), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 52/292 (17%), Positives = 99/292 (33%), Gaps = 29/292 (9%)

Query: 23  AGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTVD 82
              +  + L+K         +K C G + P             P  +    ++F      
Sbjct: 24  QRSVHTLILEK----ALFPRTKVCAGWITPRVLDLLDLSPQGYPHTIAGFDRLFFHLLGR 79

Query: 83  VAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLCRKIWREDDKWHVIFRADGW 142
             A  T  Y      I R+ FD WM     + V+VY     ++I R++ ++ +       
Sbjct: 80  TMAVKTHQY-----AIRRYEFDHWMVKR--SGVKVYP-HRVKQITRKNGQYTI------- 124

Query: 143 EQHITARYLVGADGANSMVRRHL----YPDHQIRKYVAIQQWFAEKHPVPFYSCIFDNSI 198
           +   T  YL+GA G +  V++      +P  +     A++  +            F +  
Sbjct: 125 DDTFTCNYLIGAGGTHCPVQKTFFNNDHPRSKKGLITAVEAEYRCNTRDRRCHIWFFHDR 184

Query: 199 TNCYSWSISK-DGYFIFGGAYPMKDGQTRFTTLKEKMSAF-QFQFGKTVKSEKCTVLFPS 256
              Y+W + K  GY   G        + +  T+ +   +F +     ++           
Sbjct: 185 VPGYAWYLPKQGGYVNVGIGGKAVKLKHQGRTIMDHWQSFTKTLLDLSILPYAPPHPRGH 244

Query: 257 ----RWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQP 304
               R         NA + G+AAG  +    EGI+ A++S     + +    
Sbjct: 245 TYFLRQSRLYPRIGNALVTGDAAGLATLDMGEGIAAAIESGMGAAAAITDNA 296


>UniRef50_A3TNM0 Putative oxidoreductase n=1 Tax=Janibacter sp. HTCC2649
           RepID=A3TNM0_9MICO
          Length = 340

 Score =  119 bits (297), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 65/353 (18%), Positives = 113/353 (32%), Gaps = 40/353 (11%)

Query: 5   DVAIIGLGPAG-SALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           D+ + G GP G S     +   + V       +       K CG  L P A  +     +
Sbjct: 3   DLIVAGGGPVGLSTALYAVRAGLDVGV----REPRVGVVDKACGEGLMPGAVAALRDLDV 58

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQRS-YININRHAFDLWMKSLIPASVEVYHDSL 122
            L         I  ++ VD   S    ++    + + R      +     A   V     
Sbjct: 59  DLD-----GHPITGIRYVDGTRSAQARFRYGQGLGVRRTVLHDALTRRAEAVGIVPEQRP 113

Query: 123 CRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFA 182
            R++    D   V    DG       RYL+ ADG +S VRR L     +    + ++ + 
Sbjct: 114 VREVLERGDHLLV----DGEP----TRYLIAADGLHSPVRRLL----DLSGTPSRRRRYG 161

Query: 183 EKHPVPFYSCIFDNSITNCYSWSISKDGYFI------FGGAYPMKDGQTRFTTLKEKMSA 236
           ++  V          +     WS   + Y         G A    + ++    L      
Sbjct: 162 QRAHVEMEPWTSCVEVH----WSSIGEAYVTPVAAREVGIAVLTTERRSWDDLLTHFPLL 217

Query: 237 FQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDIL 296
                G+     +     P R +     +    L+G+A+G++ A + EGI+  L      
Sbjct: 218 VGRLEGRP--HSRPLGAGPLRQRSRQRVRGRVLLVGDASGYVDALTGEGIALGLAQAKAA 275

Query: 297 RSVLLKQPEKLNTAYWRATRKL--RLKLFGKIVKSRCLTAPALRKWIMRSGVA 347
              +          Y R  R+L  R  L    + S    +P   + +  + V 
Sbjct: 276 VEAVAG---NRPADYARDWRRLGWRHDLLTHGLVSATSLSPVRHRIVHAAAVL 325


>UniRef50_Q26DN3 Putative uncharacterized protein n=1 Tax=Flavobacteria bacterium
           BBFL7 RepID=Q26DN3_9BACT
          Length = 371

 Score =  118 bits (296), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 57/363 (15%), Positives = 127/363 (34%), Gaps = 35/363 (9%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
           +++DV I G G AG   A +L+    V+ +D           K CG  L+ +        
Sbjct: 3   KNYDVIIAGGGLAGLTAAIELSQNFNVLVID----PDAYPRHKMCGEYLSLEVDDYLQSL 58

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDS 121
           G+ + +++  +       +       T +     I I+R++ D  +        +   D 
Sbjct: 59  GVNV-LELSDSKIDKFSFSQGSRTIRTASLPLGGIGISRYSLDYQLYVKAKEYSDFLCD- 116

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDH--QIRKYVAIQQ 179
               +   D+ + V       E  + A+ ++ A G  S++ + L      +   ++A++ 
Sbjct: 117 RVVDVVSFDNYYKVQTT----EFELQAKQVLIATGKRSLLDKKLERPFIQKKSPWLAVKM 172

Query: 180 WFAEKHPVPFYSCIFDNSITNCY-SWSISKDGYFIFGGAYPMKDGQ--TRFTTLKEKMSA 236
            +  + P      +  ++    Y   S  ++G          K  +      T   K+  
Sbjct: 173 HYRYEMPNDL---VELHAFHGGYAGLSKVENGDVNLCYLVNYKTFKRYKNINTFNHKVLK 229

Query: 237 FQFQFGKTVKSEKCTVLFPS-----RWQDFVCGKDNAFLIGEAAGFISASSLEGISYALD 291
                 K + +       P       ++          +IG+ AG I      G++ A+ 
Sbjct: 230 VNKVLCKFLNTAVPVWDKPITISQISFEQKEPIHGKLIMIGDTAGLIHPLCGNGMAMAIH 289

Query: 292 STDILRSVLLK------QPEKLNTAY---WRATRKLRLKLFGKIVKSRCLTA--PALRKW 340
           S       + +         +L + Y   W+ T   RL+ +G+ ++   L     ++  W
Sbjct: 290 SAQKASHYVTQFLNQDINQAQLLSNYSKDWKRTFSSRLR-YGRWLQKILLNKSSSSIAYW 348

Query: 341 IMR 343
           +++
Sbjct: 349 LLK 351


>UniRef50_A1T3S9 Geranylgeranyl reductase n=10 Tax=Actinomycetales
           RepID=A1T3S9_MYCVP
          Length = 418

 Score =  118 bits (296), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 55/322 (17%), Positives = 97/322 (30%), Gaps = 34/322 (10%)

Query: 27  QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTVDVAAS 86
            V+ +D           K CG  L P A     R GL   +D     +   +        
Sbjct: 41  DVLVID----SAQFPRDKACGDGLTPRAIAELRRLGLQSWLDGRIAHRGLRMSGFGADVE 96

Query: 87  LT---RNYQRSYININRHAFDLWMK-SLIPASVEVYHDSLCRKIWREDDKWHVIFRADGW 142
           +     ++      + R   D  ++   +    ++        + R      V       
Sbjct: 97  VAWPGPSFPSISSAVPRTELDERIRLVAVDDGAKMKLGVKAVSVERGSGG-RVTGVVLDT 155

Query: 143 EQHITARYLVGADGANSMVRRHLYPDHQIRKY--VAIQQWFAEKHPVPFYSCIF------ 194
            + +  R L+ ADGA S + R L  +        VAI+ + A       +          
Sbjct: 156 GEVVRCRDLIVADGARSTLGRALGREWHKETVYGVAIRGYIATPRSDEPWITSHLELRSP 215

Query: 195 DNSITNCYSWSIS-KDGYFIFGGAYPMKDGQTRFTTLK------EKMSAFQFQFGKTVKS 247
              +   Y W     +G    G        +     L+        +   ++ F    + 
Sbjct: 216 AGEVLPGYGWIFPLGNGEVNIGVGALATAKRPADAALRPLMNYYAGLRRDEWGFSGDPR- 274

Query: 248 EKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKL 307
              + L P           N  LIG+AA  ++  + EGI Y L++  +  S+L       
Sbjct: 275 AGLSALLPMGGAVSGVAGPNWMLIGDAAACVNPLNGEGIDYGLETGRLAASLL---GSGS 331

Query: 308 NTAYWRATRKLRLKLFGKIVKS 329
            +A W A       L G   + 
Sbjct: 332 YSAAWPAL------LHGHYARG 347


>UniRef50_A8THG7 Geranylgeranyl reductase n=1 Tax=Methanococcus voltae A3
           RepID=A8THG7_METVO
          Length = 422

 Score =  118 bits (296), Expect = 3e-25,   Method: Composition-based stats.
 Identities = 51/378 (13%), Positives = 109/378 (28%), Gaps = 47/378 (12%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
           E +DV I+G GPAG   A  +   + V+ +++    G       C GLL+          
Sbjct: 11  EQYDVIIVGGGPAGFITAENIQKDLNVLVVEEHQSIG---VPIQCAGLLSKKGFNEL--- 64

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLI---------- 111
               P  ++   +  ++       ++  + +   +   R   D  +              
Sbjct: 65  --GNPKGIVNKVRGANIFCEKQNLTVGDDNKIRAMVFERKEMDKDIAKRALKNKNVNLML 122

Query: 112 PASVEVYHDSLCRKIWREDDK-----------WHVIFRADGWEQHITARYLVGADGANSM 160
            +  ++ +++   K  +                 V       +   + + +VGADG  S 
Sbjct: 123 KSHGKILNETTTNKNNKNSKNSKNNSLNKKHIIEVKNNLKDEKYIFSPKIIVGADGVRSG 182

Query: 161 VRRHLYPDHQIRKYVAIQQWFAEKHPV--PFYSCIFDNSI-TNCYSWSISKDGYFIFGGA 217
           + + L    +      +Q  +     +   F +  +D    +N ++W I      +  G 
Sbjct: 183 IGKSLKMHQKREIITGVQIEYVNVSNIDSDFVNVFYDKRYSSNFFTWIIPTGKDRVRVGM 242

Query: 218 YPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGF 277
              KD   +           +         E      P  +       +N  L+G+A   
Sbjct: 243 CDTKDALNKLNNFIATNENAKEILKGATPIEYSIGAIPLGYNSKSVL-NNVMLVGDAVNQ 301

Query: 278 ISASSLEGISYALDSTDILRSVLLK--------------QPEKLNTAYWRATRKLRLKLF 323
           +   S  G+ +      +  + + +                      Y    +    K  
Sbjct: 302 VKPLSGGGLYFGAKCAKLCANTINEYYTKYHTKFLNEENANLDYLKTYEELWKSEIGKEI 361

Query: 324 GKIVKSRCLTAPALRKWI 341
              +K   L      K I
Sbjct: 362 NYGLKMSYLMNKLNNKKI 379


>UniRef50_D0L4V5 Geranylgeranyl reductase n=6 Tax=Actinomycetales RepID=D0L4V5_GORB4
          Length = 435

 Score =  118 bits (296), Expect = 3e-25,   Method: Composition-based stats.
 Identities = 57/352 (16%), Positives = 111/352 (31%), Gaps = 44/352 (12%)

Query: 26  MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL------TLPVDVIANPQIFSVK 79
             V+ +D           K CG  L P A     R GL         ++ +      + K
Sbjct: 48  HDVVLVD----AAVFPRDKTCGDGLTPRAVAELDRLGLGHFLADRPRIEGLHLHGWGADK 103

Query: 80  TVDVAASLTRNYQRSYININRHAFDLWMKS-LIPASVEVYHDSLCRKIWREDDKWH-VIF 137
            V   A     +      + R   D  +++  +     +   +    +    D+   V  
Sbjct: 104 RVPWPA---GRFPAHGSAVARTELDDAIRAFAVSKGARMIQGAKAVDVTMSGDRIESVTL 160

Query: 138 RADGWEQHITARYLVGADGANSMVRRHLYPD-HQIRKY-VAIQQWFAEKHPVPFYSCIF- 194
            +      + A +++ ADG  S + + L  + H+   Y VA + +         +     
Sbjct: 161 SSAAGTSAVRAEHVIVADGVRSGLGKILGREWHRDTAYGVAARAYVRSGRADDAWMGSHL 220

Query: 195 -----DNSITNCYSWSIS----KDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKTV 245
                + ++   Y W        DG    G        +     L+  +  +        
Sbjct: 221 ELRGPEGTLLPGYGWVFPLGSAGDGLLNVGVGALATSKRPAHMQLRPVLEFYTDMVRDEW 280

Query: 246 KSEKCTV-----LFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVL 300
             +   V     L P           N  LIG+AA  ++  + EGI YAL++  +   ++
Sbjct: 281 AVDGSPVRLTSALLPMGGAVSGVAGRNWMLIGDAAACVNPLNGEGIDYALETGRLAIELI 340

Query: 301 LKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAHIPQL 352
                + +  +      + +  +G       L   A R+    +GV  +PQ 
Sbjct: 341 --DDTRADPDHTTRWPAILVDHYG-------LAFSAARRL---AGVLTVPQA 380


>UniRef50_Q2FLI3 Geranylgeranyl reductase n=1 Tax=Methanospirillum hungatei JF-1
           RepID=Q2FLI3_METHJ
          Length = 384

 Score =  118 bits (295), Expect = 3e-25,   Method: Composition-based stats.
 Identities = 64/324 (19%), Positives = 111/324 (34%), Gaps = 30/324 (9%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
             +DVAI+G GP GS  AR  A   ++ + ++++      G+   C GLL+  A R    
Sbjct: 3   RTYDVAIVGGGPVGSTAARICAKSGLKTLLIEEQAH---FGYPVQCAGLLSDSAFRECEV 59

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVYH 119
              ++   V          T    A  T  Y      ++R A D  M K+   A  ++  
Sbjct: 60  SCSSVLNTVSGADVHAGEATCSFDAGRTMAY-----VVDRGALDHEMGKAAADAGADIQL 114

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQ 179
            ++   I R     H+  +     + ++   L+ ADG  S + R +           +Q 
Sbjct: 115 KTIASGISRTSGILHL--KGVNGPEDVSYSMLIAADGPRSSISRMVGIPRAPVYLSGLQC 172

Query: 180 WFAEKHPVPFYSCIFDNSITNCYSWSIS-KDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQ 238
                 P P +  I+ N+    + W I         G              +KE+ S F 
Sbjct: 173 DVHHALP-PDHVQIYPNASPEFFGWMIPLHPDQTRIG--------LCGIHHVKERFSEFI 223

Query: 239 FQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRS 298
             F     +   +   P          D   + G+AA     +S  G+   + +      
Sbjct: 224 KPFQNKA-THFVSGTIPLGTLTRSY-DDRILIAGDAAAMAKPTSGGGVYTGIRAARHAAE 281

Query: 299 VLLKQPE------KLNTAYWRATR 316
           V ++  E      K   +Y  A +
Sbjct: 282 VAIRCIEMDDFSPKAMASYEHAWK 305


>UniRef50_B2J4Q2 FAD dependent oxidoreductase n=1 Tax=Nostoc punctiforme PCC 73102
           RepID=B2J4Q2_NOSP7
          Length = 371

 Score =  117 bits (294), Expect = 4e-25,   Method: Composition-based stats.
 Identities = 63/360 (17%), Positives = 116/360 (32%), Gaps = 43/360 (11%)

Query: 6   VAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           + ++G GPAG +    LA    +V+ +DK          K CG  ++  + ++    G+ 
Sbjct: 4   IVVLGAGPAGCSAGYHLAKSGHKVMLIDKD----CFPRDKTCGDGISLGSVQALSTMGI- 58

Query: 65  LPVDVIANPQIFS-----VKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYH 119
            P D+      ++     +  V    S     +     I R  FD  +      +  V  
Sbjct: 59  YPDDIKRLASEYAQIDGFLLGVSNEISHLCPTELKGYCIPRFVFDNLLYQKAINAGCVAR 118

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQ 179
                 I      +H    +D         Y++ A G  +     +     IR Y +I+ 
Sbjct: 119 TQRISDIE----GYHQELYSD-------FDYIIDARGVYAGEANAIA----IRAYWSIKV 163

Query: 180 WFAEKHPVPFYSCIFDNSIT-NCYSWSISKDG-----YFIFGGAYPMKDGQTRFTTLKEK 233
               K  +      FD +   N Y W               G    + + Q   T +   
Sbjct: 164 ADFPKIYLSKAQIYFDKAFGVNGYGWIFPVAVDSELVKLNVGVGVWLDEYQKNNTNIIRL 223

Query: 234 MSAF--QFQFGKTVKSEKCTVLFPSRWQDFVCGKDN------AFLIGEAAGFISASSLEG 285
            + F  + Q  K + S   +   P  +      + N       F IG+AA      + EG
Sbjct: 224 FNEFVQRNQATKQLLSLVVSQQKPKAYPLATAKRANTVSYGKVFKIGDAANLTDPLTGEG 283

Query: 286 ISYALDSTDILRSVLLKQPEK-LNTAYWRATRKLRLK--LFGKIVKSRCLTAPALRKWIM 342
           I+ A+ S   +   +       L +  W+   +L  +  L   +          + K ++
Sbjct: 284 IANAILSGLYVTQAINMSTSPELASENWQRLYQLYFEPDLDAGLQIKSFRKFSFINKLLI 343


>UniRef50_A1RWE4 FAD dependent oxidoreductase n=1 Tax=Thermofilum pendens Hrk 5
           RepID=A1RWE4_THEPD
          Length = 399

 Score =  117 bits (294), Expect = 5e-25,   Method: Composition-based stats.
 Identities = 61/330 (18%), Positives = 110/330 (33%), Gaps = 27/330 (8%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
             ++  +IGLGPAG+A  ++L    ++ + +++K           CG  L   +   FI 
Sbjct: 6   GRYEAVVIGLGPAGAAALKRLQELGIKAVGIERKKAPEE---PAVCGEFLPEPSAIEFIS 62

Query: 61  DGLTLPVDVIANPQIFSVKTV-----DVAASLTRNYQRSYININRHAFDLWMKSLIPASV 115
              ++               +       A   T N +     ++R      M S +    
Sbjct: 63  RFPSVRKAYEYIGLARRTNAIRRIILSFAGGKTYNLEIPGFTVSRKE----MVSKLIEGS 118

Query: 116 EVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKY- 174
           +    S    I R  D + V  R     +  +A Y++ ADG  S  RR L     ++   
Sbjct: 119 DYVTGSDVVGIRRVGDAYLVKTRR---GKEFSASYVIAADGFPSATRRLLGLPAGLQPED 175

Query: 175 VAIQQWFAEKHPVPFYSCIFDNSIT---NCYSWSIS-KDGYFIFGGAYP---MKDGQTRF 227
            A+      + P      IF  + +     Y+W I   DG    G       +K G    
Sbjct: 176 YAVGVNLKMETPSMPRDTIFMYASSFTQGGYAWIIPVGDGLSNVGIGLRFNYVKKGANPL 235

Query: 228 TTLKEKMSAFQFQFGKTVK--SEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEG 285
             L   +   +  F  + +   E  + + P                G++ G ++  +  G
Sbjct: 236 KALTSFVELERRGFLDSSRQLEEPRSRMIPVSGFYSEPSTGKVLFAGDSLGAVNPINGGG 295

Query: 286 ISYALDSTDILRSVL-LKQPEKLNTAYWRA 314
           I  A+    +    + L  P   +   WR 
Sbjct: 296 IFTAMALGILAAESVWLGNPGIYDERSWRE 325


>UniRef50_C4RL56 Alkylhalidase cmlS n=1 Tax=Micromonospora sp. ATCC 39149
           RepID=C4RL56_9ACTO
          Length = 656

 Score =  117 bits (293), Expect = 5e-25,   Method: Composition-based stats.
 Identities = 59/362 (16%), Positives = 105/362 (29%), Gaps = 35/362 (9%)

Query: 6   VAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTL 65
           VAIIG GPAG      L      + + ++ +          G  L P       R GL  
Sbjct: 92  VAIIGGGPAGCVAGLTLHKLGHDVTIYERDRFPRYRI----GESLLPGTMSILNRLGLQE 147

Query: 66  PVD----VIANPQIFSVKTVDVAASLTRNYQRSY-------ININRHAFDLWMK-SLIPA 113
            +D    V      F         + +    +         I + R  FD  +       
Sbjct: 148 RIDAEDFVKKPSATFLWGQDQAPWTFSFAAPKVAPWVFDHAIQVKREVFDNLLLDEARSR 207

Query: 114 SVEVYHDSLCRKIW-REDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIR 172
            + V  ++    +     D   +  R DG    + + +++ A G+   + R L       
Sbjct: 208 GIAVLEETPVTGVDLSGADGVALTIRQDGKATRVESDFVIDAGGSGGPLVRQLGVRRYDE 267

Query: 173 KY--VAIQQWFAEKHPV--PFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFT 228
            Y   A+  +F  K P         +  +  + + W I   G     G    +       
Sbjct: 268 FYKNFAVWSYFQRKDPFEGDLKGTTYSITFEDGWVWMIPMKGDLYSVGLVVDRTKSAEVR 327

Query: 229 TL---------KEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFIS 279
            L           K              +   ++    +   V   D  FL G+AA F  
Sbjct: 328 QLGADAFYRSTLAKCGKAMDLLAGAKMVDDVRIVHDWSYDTEVFSADRFFLCGDAACFTD 387

Query: 280 ASSLEGISYALDSTDILRSVL-----LKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTA 334
               +G+  A  S     + +      K       A++  T +   + + + + S    A
Sbjct: 388 PLFSQGVHLASQSAVCAAAAIDRITHNKDETDAVHAWYNRTYREAYEQYHEFLASFYTFA 447

Query: 335 PA 336
             
Sbjct: 448 SF 449


>UniRef50_UPI0001744EC4 Putative Dehyrogenase n=1 Tax=Verrucomicrobium spinosum DSM 4136
           RepID=UPI0001744EC4
          Length = 423

 Score =  117 bits (293), Expect = 6e-25,   Method: Composition-based stats.
 Identities = 72/350 (20%), Positives = 118/350 (33%), Gaps = 39/350 (11%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           +DV IIG GPAGS+ A  LA   + + + +K +          G  L P  ++ +   G+
Sbjct: 11  WDVVIIGGGPAGSSAATTLAQAGRKVLVLEKEKFPRFHI----GESLLPYNRQVYEELGV 66

Query: 64  T--LPVDVIANPQIFSVKTVDVAASLTRNYQRS-------YININRHAFDL-WMKSLIPA 113
              +        +       D    +  ++ +         + + R  FD   +      
Sbjct: 67  WEKISQAGFMRKKGAQFLLGDGTRKVRLDFSKGSFTEFPEAVQVERAKFDNILLTHSQEC 126

Query: 114 SVEVYHDSLCRKIWREDDKWHVIFR-ADGWEQHITARYLVGADG-----ANSMVRRHLYP 167
             EV  +SL + +  + D   V +R  +G    + A++L+ A G     AN   RR  Y 
Sbjct: 127 GAEVRQESLVQDLQVDADGVAVKYRDKEGASHQVKAKFLIDASGLSNFTANRENRRTYYA 186

Query: 168 DHQIRKYVAIQQWFAEKH--PVPFYSCIFDNSITNCYSWSIS-KDGYFIFGGAYPMKDG- 223
           +H+    +AI   FA         Y  I      N + W I  +D     G      D  
Sbjct: 187 EHKK---IAIFNHFAGVDMPQGEEYGDILVIRRNNSWFWMIPLEDDKVSVGLVMDRGDFQ 243

Query: 224 ------QTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGF 277
                 +  F        A Q +F K        V     +++     D     G+A+GF
Sbjct: 244 ALGQEPRQVFEEAVRTTPAVQERFTKVAPPASVHVATDFSYRNNSLVSDRVIRAGDASGF 303

Query: 278 ISASSLEGISYALDSTDILRSVLLKQPE------KLNTAYWRATRKLRLK 321
           I      G+  A  S      V  +  +          AY   TR    +
Sbjct: 304 IDPVFSSGVLLATTSGRQAGLVADEAIKLGESMTPAMQAYETDTRNRIGQ 353


>UniRef50_B8FXK4 Electron-transferring-flavoprotein dehydrogenase n=6 Tax=Bacteria
           RepID=B8FXK4_DESHD
          Length = 432

 Score =  117 bits (292), Expect = 7e-25,   Method: Composition-based stats.
 Identities = 61/358 (17%), Positives = 121/358 (33%), Gaps = 52/358 (14%)

Query: 3   HFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            ++V IIG G AG + A KLA   M+V+ +++    G++  S   GG+L        I D
Sbjct: 5   KYEVIIIGAGLAGLSAAYKLAKAGMEVVVVERGDYPGSKNLS---GGVLYSRILDQLIPD 61

Query: 62  G-LTLPVDVIANPQIFS------VKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPA 113
                P++      + +         ++           + + + R  FD W+ +    A
Sbjct: 62  FWEEAPIERYITNYLTTLMTPTDYVNIEYKDQELAKPPYNAVTVLRAKFDRWLAEKAEEA 121

Query: 114 SVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRK 173
              +       K+ +E  +   I   D   + + A  ++ ADG NS + +      +I  
Sbjct: 122 GAMIVTGVKVDKVLKEGGRITGITTGD---EEMLADVVIAADGINSFIAQEAGLRGEIEP 178

Query: 174 YV--------------AIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYP 219
                           AI++ F  +        +  ++                      
Sbjct: 179 AHLAVGAKALIELPQQAIEERFRLEGNEGTAYAMLGDATHGVAGGGFFYTNRESLSIGVV 238

Query: 220 M------KDGQTRFTTLKEKMSAFQF----------QFGKTVKSEKCTVLFPSRWQDFVC 263
           M      K+    F  L + +               ++G  + +E    + PS+      
Sbjct: 239 MRLDDLVKEKVKPFEVLDDLLRHPLVAPLVKDGTMTEYGAHLTAEGGVHMVPSQ-----L 293

Query: 264 GKDNAFLIGEAAGFI--SASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLR 319
             D   ++G+AAGF   S   + G+  A+ S       +L+  E+ + +    +   R
Sbjct: 294 HTDGMLIVGDAAGFTINSGLVIRGMDLAIGSGMAAAEAVLEAKERGDYSAAALSSYQR 351


>UniRef50_A8ZT45 FAD dependent oxidoreductase n=1 Tax=Desulfococcus oleovorans Hxd3
           RepID=A8ZT45_DESOH
          Length = 357

 Score =  117 bits (292), Expect = 7e-25,   Method: Composition-based stats.
 Identities = 70/334 (20%), Positives = 107/334 (32%), Gaps = 51/334 (15%)

Query: 6   VAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTL 65
           + I+G GPAG   A  LA          + Q      S  C   ++ D  +   R     
Sbjct: 3   IIIVGGGPAGLITALCLARMHGAEICLHEKQGPPAYTSSLCAEGISRDMLQRLERHTGFD 62

Query: 66  PVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIP----ASVEVYHDS 121
               I+         V           +    + R A   W +++        VEV+ +S
Sbjct: 63  STPFISRAVCG--IQVHFPGGKCGYLHQPGATLERTA---WQQAMAEFAGRRGVEVFWES 117

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWF 181
               I   D                 A  +VGADG  S +R  +     +    A+Q   
Sbjct: 118 RVSGIDELD-----------------ADVVVGADGPASRIRTAIG--GTVDMVPAVQYRM 158

Query: 182 AEKHPVPFYSCIFDNSI-----TNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSA 236
               P  F     D         + Y+W   K   F  G        +  F  L   +SA
Sbjct: 159 NLDRPREFLEFFIDERFYHGKHNDGYAWIFPKKDSFNVG-------VKGSFEQLDLFLSA 211

Query: 237 FQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDIL 296
           F  + G+        +       +    +   FLIG+AAG  +A++  G++  +   D L
Sbjct: 212 FDIR-GEITHRGGAPIAVHGTRFEGTLDRRKVFLIGDAAGLTNAATCGGLNPIIACADFL 270

Query: 297 RSVLLKQPEKLNT----------AYWRATRKLRL 320
           R  +  Q E   T          AYW+A R L  
Sbjct: 271 RQAVGWQEEGAYTRLIKTHHYDPAYWKAVRHLFY 304


>UniRef50_C7DGR0 Geranylgeranyl reductase n=1 Tax=Candidatus Micrarchaeum
           acidiphilum ARMAN-2 RepID=C7DGR0_9EURY
          Length = 368

 Score =  117 bits (292), Expect = 8e-25,   Method: Composition-based stats.
 Identities = 58/316 (18%), Positives = 99/316 (31%), Gaps = 18/316 (5%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
           + +D  I+G    G   AR+L+ K  V+ ++     GT      C G +   A   F  D
Sbjct: 3   KRYDCVIVGGSITGLTAARELSKKASVLLVESNPAIGTPFR---CSGFINAPAFEEFALD 59

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDS 121
              +   +        V       +        ++   R A +  +   I    ++    
Sbjct: 60  KSQIQNSISR----LEVVHGGSRLTFASKKPSGFVT-ERPALERSLLGEIEPYTDIVAGD 114

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWF 181
               I        V     G   +++A  L+GADG NS+VRR +       K  A+Q   
Sbjct: 115 RVVDIK----GATVSLHTSG---NVSAGCLIGADGTNSLVRRSIGIADP-EKVTAVQFEL 166

Query: 182 AEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQF 241
                    +          + W I  +      G     D +     L E +  ++   
Sbjct: 167 PGSFESDCATIYVGEEFMPFHLWVIPVNESLARIGVGASGDVKAGMQRLLELVKKYKIAD 226

Query: 242 GKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLL 301
                  +  V           G  +  L G + G I   SL GI + + S+ +    L+
Sbjct: 227 YPRYSESRFMVNTLPASPVSSTGTGSTMLAGMSGGIIKPLSLGGIYFGMLSSSMAARSLI 286

Query: 302 KQPEKLNTAYWRATRK 317
                L + Y R    
Sbjct: 287 DG--TLASGYRRKLEN 300


>UniRef50_A1HMV3 FAD dependent oxidoreductase n=1 Tax=Thermosinus carboxydivorans
           Nor1 RepID=A1HMV3_9FIRM
          Length = 458

 Score =  117 bits (292), Expect = 8e-25,   Method: Composition-based stats.
 Identities = 60/331 (18%), Positives = 109/331 (32%), Gaps = 46/331 (13%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGG--LLAPDAQRSF 58
           + +D  ++G GPAGS  A  +A   + V+ L++    G    +K CGG  ++A    + F
Sbjct: 31  KKYDAIVVGAGPAGSTAAYFMAKEGLDVLLLER----GPYPGAKCCGGVSIIAEHVHKLF 86

Query: 59  IRDGLTLPVDVIANPQIFSVKTVDVAASLTRNY------QRSYININRHAFDLWM-KSLI 111
                  P + I   Q +   T D   +             +   I R  F  W+    I
Sbjct: 87  PNFWEECPYERIVTDQAYWWMTEDSILTARFRSTKLAAAPYNRFTIKRVNFYKWLTAKAI 146

Query: 112 PASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMV--RRHLYPDH 169
            A   +  +    ++  +  +   +  +        A  ++ ADGANSM+  R  L P  
Sbjct: 147 SAGTTLLLNHHVSEVLFDGQQAIGVHVSPPQNSDFIADIIILADGANSMLAERAKLAPQI 206

Query: 170 QIRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSI------------------SKDGY 211
             R +     +  E   +P        ++   +   I                   KD +
Sbjct: 207 SPRNFA---LYVKETIALPAKVIEERFNLLPGHGTIIGLIGYPTAGFNGTGSIHTFKDSF 263

Query: 212 FIFGG--AYPMKDGQTRFTTLKEKMSAF-----QFQFGKTVKSEKCTVLFPSRWQDFVCG 264
            I  G     +         L E++            G T++     +     +      
Sbjct: 264 NINVGISLADLAKAGFNPNDLLERIKKHPHMQPLLDGGTTIEYGAALIPEGGYYAMPELV 323

Query: 265 KDNAFLIGEAAGFISASSLEGISYALDSTDI 295
                +IG+AA  ++     GI+ A+ S   
Sbjct: 324 HPGLMIIGDAASLVNGV--HGINLAMWSGFF 352


>UniRef50_A2BM78 Predicted Dehydrogenase n=1 Tax=Hyperthermus butylicus DSM 5456
           RepID=A2BM78_HYPBU
          Length = 454

 Score =  116 bits (291), Expect = 9e-25,   Method: Composition-based stats.
 Identities = 54/318 (16%), Positives = 104/318 (32%), Gaps = 23/318 (7%)

Query: 4   FDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +DV + GLGPAGS     LA    +V+ +++      + +SKPCG  L   A        
Sbjct: 7   YDVIVAGLGPAGSVALWHLARMGFRVLGIERNR--PEKLWSKPCGDAL--GAHHITESHL 62

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVYHDS 121
              P  V+ N ++ ++     +  +          I+R AF  W+ +  +    EV +++
Sbjct: 63  PEPPSSVLKN-RVTAIDIYSPSEEVRYRVHGKGYIIDRTAFGRWLVEDALNRGAEVLYET 121

Query: 122 LCRK-IWREDDKWHVIFRA-DGWEQHITARYLVGADGANSMVRRHLYPD-------HQIR 172
              + I        V  ++ DG    + A  ++ A G + ++RR L  D           
Sbjct: 122 SILEPIISGGKVIGVKAKSKDGRVVELYASLVIEATGFSRVIRRRLPRDWPIYEDIDPRD 181

Query: 173 KYVAIQQWFAEKHPVPFYSCIFD-----NSITNCYSWSISKDGYFIFGGAYPMK--DGQT 225
             +A ++    +        +             Y W   +  +    G          +
Sbjct: 182 TNIAYREIIEYEDYEIEEPNVIRIYLNQEIAPGGYWWFFPETSHRSNVGLGVQGGMGYPS 241

Query: 226 RFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEG 285
                +EK+        K           P+R            +IG+A   ++     G
Sbjct: 242 PMQIYREKLVEHSLLRLKHRVITAAGAPLPTRRPSNTMVGPGVVVIGDAGYTVNPIHGGG 301

Query: 286 ISYALDSTDILRSVLLKQ 303
           + Y   +         + 
Sbjct: 302 MGYGFRAAYYAAKAFEEA 319


>UniRef50_Q9YAI8 Putative uncharacterized protein n=1 Tax=Aeropyrum pernix
           RepID=Q9YAI8_AERPE
          Length = 463

 Score =  116 bits (291), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 67/309 (21%), Positives = 111/309 (35%), Gaps = 33/309 (10%)

Query: 3   HFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            +DV I+GLGPAGS+LA  L    ++V  LD        G  KPCG  +       F+  
Sbjct: 6   KYDVVIVGLGPAGSSLAYLLKDTGLKVAGLDIADFNRVWG--KPCGDAIGKG---HFLET 60

Query: 62  GLTLPVDVIANPQIFSVKTVDVAAS-----LTRNYQRSYININRHAFDL-WMKSLIPASV 115
           GL LP        +  V  VD+ +      +  +       I+R+ + L  ++    + V
Sbjct: 61  GLPLPK---GEAMMQVVNAVDIYSPSEEVKIRLSEPEGGFMIDRNKYGLQLLEEAQKSGV 117

Query: 116 EVYHDSLCRKIWREDDK-WHVIFRADGWEQ----HITARYLVGADGANSMVRRHL----- 165
           +VY  +       E+ +   V  +  G +        ++ +V A G+   ++R L     
Sbjct: 118 DVYLKTHALSPIIENGRLVGVYAKRHGEDGDVNVKFYSKIIVDATGSGGAIKRKLPSSWP 177

Query: 166 --YPDHQIRKYVAIQQW----FAEKHPVPFYSCIFDNSITNCYSWSISKDGYF-IFGGAY 218
              P       VA ++     +  + P      I  +     Y W   K       G   
Sbjct: 178 VVEPLKPTDSAVAYRKIVELDYDIEEPDVIRIYINADIAPGGYWWLFPKGRRIANIGIGV 237

Query: 219 PMKDGQTRFTTLKEKMSAFQFQFGKTVKSE-KCTVLFPSRWQDFVCGKDNAFLIGEAAGF 277
               G      L EK    +   G+ V+   +   L P+R        DN   IG+ A  
Sbjct: 238 QRGRGYPHPRHLYEKYLDKRPDTGRVVRLLNEAGALLPTRRPANTIVWDNFVSIGDNAYT 297

Query: 278 ISASSLEGI 286
           ++     G+
Sbjct: 298 VNPVHGGGM 306


>UniRef50_Q9HLA3 FixC protein related n=2 Tax=Thermoplasma RepID=Q9HLA3_THEAC
          Length = 428

 Score =  116 bits (289), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 75/356 (21%), Positives = 126/356 (35%), Gaps = 44/356 (12%)

Query: 1   MEHFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M  FDV +IG GPAGS+ A KLA G M V+ +++    GT+  S   G +L  D     +
Sbjct: 1   MSEFDVIVIGAGPAGSSAAIKLAQGGMNVLLVERGDPPGTKNVS---GAVLWGDELSKVV 57

Query: 60  RD-GLTLPVDVIANPQIFSVKTVDVAASLTRNYQR-----SYININRHAFDLWMKSLIPA 113
            D   + P++     +  +  T     +++ + Q      S   I R  FD W+      
Sbjct: 58  PDWERSAPIERYVTRKEVAFLTEKSKIAISYSSQELMEKKSGKIIVRGKFDQWLARKAKD 117

Query: 114 SVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRK 173
           +  +    +       D    +    DG    IT+  ++ A+GAN  V  +     ++  
Sbjct: 118 AGAMLVTGITVDKLVIDGGKVIGVMQDGD--VITSDAVIVAEGANPRVLINSGLRPKLSD 175

Query: 174 Y-VAIQQWFAEKHPVPFYSCIFDNSITNCYS----WSISKDGYFIFGGAYPMKDG----- 223
           + VA+      K P    +  F+      Y+         DG    G  Y  +D      
Sbjct: 176 HDVALGIKETIKLPENVINERFNVDSKGGYASEFVLGFLDDGLLSGGFLYTNRDTISLGI 235

Query: 224 --------QTRFTTLKEKMSAFQFQ------FGKTVKSEKCTVLFPSRW--QDFVCGKDN 267
                       T   + M  F+            +  E    L P            + 
Sbjct: 236 VTSLDRLRANGMTHSYDIMGKFEDHPFIKNLIKDGIPDEYAAHLVPEGGLASMPKLYGNG 295

Query: 268 AFLIGEAAGFI--SASSLEGISYALDSTDILRSVLLKQ----PEKLNTAYWRATRK 317
             + G+AA F   +   L+GI+YA+ S  +    +L+      E+  + Y    R 
Sbjct: 296 YLVAGDAAMFTFSNGMVLQGINYAITSGMLAAETILENKGKISEETLSTYVSKLRN 351


>UniRef50_Q0SF87 Possible dehydrogenase n=23 Tax=Actinomycetales RepID=Q0SF87_RHOSR
          Length = 420

 Score =  115 bits (287), Expect = 3e-24,   Method: Composition-based stats.
 Identities = 54/317 (17%), Positives = 100/317 (31%), Gaps = 21/317 (6%)

Query: 40  EGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTVDVAASLT---RNYQRSYI 96
               K CG  L P A       GL   V      +   +        L    R++     
Sbjct: 50  FPRDKTCGDGLTPRAVAELDHLGLGDWVRSKGTNRGLRLSGFGQELELEWPGRSFPAVGS 109

Query: 97  NINRHAFDLWMKS-LIPASVEVYHDSLCRKIWREDDKWH-VIFRADGWEQHITARYLVGA 154
            + R   D  +++  + A   +   +    + R+ D+   V  +       I  R L+ A
Sbjct: 110 AVARTELDDRIRATAVDAGAVMVQGAKAIGVERDGDRVTAVALKTSDGAHTIGCRTLIVA 169

Query: 155 DGANSMVRRHLYPD-HQIRKY-VAIQQWFAEKHPVPFYSCIF------DNSITNCYSWSI 206
           DG  S + + L  + H+   Y VA + + A       +            ++ + Y W  
Sbjct: 170 DGVRSTLGKQLGREWHRDTAYGVAARAYIATDRSADPWITSHLELRDGAGTLQSGYGWVF 229

Query: 207 S-KDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEK-----CTVLFPSRWQD 260
               G    G        +     L+  +  +  Q     K +       + L P     
Sbjct: 230 PLGTGEVNIGVGTLATAKRPAPGALRPLLDLYTAQRRDEWKWDGELRAVASALLPMGGAV 289

Query: 261 FVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRL 320
                 N  +IG+AA  ++  + EGI Y L+   ++  +L    + L   +    R+   
Sbjct: 290 SHIAGRNWAIIGDAAACVNPLNGEGIDYGLEGGRLVAEIL--DSDDLTELWPAILRERYG 347

Query: 321 KLFGKIVKSRCLTAPAL 337
           + F    +   L     
Sbjct: 348 RAFSVARRLAGLLTVPR 364


>UniRef50_D2PPR1 Geranylgeranyl reductase n=2 Tax=Actinomycetales RepID=D2PPR1_9ACTO
          Length = 375

 Score =  114 bits (286), Expect = 4e-24,   Method: Composition-based stats.
 Identities = 61/336 (18%), Positives = 111/336 (33%), Gaps = 27/336 (8%)

Query: 20  RKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVK 79
           R  A ++ V+ LD+          K CG  +AP         G+T  +D     +  ++ 
Sbjct: 24  RAAAPELTVVMLDRSD----FPRDKTCGDGIAPHVLDLLGEVGVTGLLDDWTPVRRLAL- 78

Query: 80  TVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLCRKIWREDDKWHVIFRA 139
                  + R   R    + R  FD  +     A+         R +    D   +    
Sbjct: 79  -ERGPHVVDRAMTRPNWVVPREVFDHRLVLAAQAAGVQLVRHRVRGLSVYRDVVRI---- 133

Query: 140 DGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEKHPV-PFYSCIFDNSI 198
              +  + A+ ++GADGA S+VR       +    +A++ +           + ++    
Sbjct: 134 ---DDQLAAKIVIGADGAASVVR-RAGGGGRGPVALALRGYAPTPPERAGRQAIVYGPGT 189

Query: 199 TNCYSWSI-SKDGYFIFGGAYPMKDGQTRFT--TLKEKMSAFQFQFGKTVKSEKCTVLFP 255
              Y+WS    DG    G    +   +   T   L  K+              +   L  
Sbjct: 190 QPSYAWSFDRGDGLCNVGYGEALTARRPHPTRAELLGKLEHLLPGATAGGAQWRAHHLPL 249

Query: 256 SRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDS-----TDILRSVLLKQPEKLNTA 310
           S W           L G+AAG I+  + EGI YA+ +          ++         TA
Sbjct: 250 SSWSWRPP-DGRVLLAGDAAGLINPMTGEGIYYAVATGLLAGRAAAGAIRTGDEGGAGTA 308

Query: 311 YWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGV 346
           Y  +T   R+ L   +  +      +    ++  G+
Sbjct: 309 YRAST---RVALGRHLWHTALAARLSGSPLVLDRGI 341


>UniRef50_Q3A9B4 FixC protein n=1 Tax=Carboxydothermus hydrogenoformans Z-2901
           RepID=Q3A9B4_CARHZ
          Length = 431

 Score =  114 bits (285), Expect = 5e-24,   Method: Composition-based stats.
 Identities = 58/336 (17%), Positives = 114/336 (33%), Gaps = 38/336 (11%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPD--AQRSF 58
           E FDV ++G GP+G A A KLA   ++VI +++    G    +K   G +      +  F
Sbjct: 3   EKFDVVVVGAGPSGLAAAYKLAEAGLKVIVIER----GEFPGAKNVMGGIIYKKPTEAVF 58

Query: 59  IRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQR-----SYININRHAFDLWMKSLIPA 113
                  PV+     Q +   T       +    R     S  ++ R  FD ++   +  
Sbjct: 59  PEIFKEAPVERPIIEQRYYFLTDTAKIGFSYRNPRYKEDISGYSVFRAKFDRFLAKKVQE 118

Query: 114 -SVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQI- 171
               +  +++   +  +D K   +      E  + A  +V A+GA+S++ +       I 
Sbjct: 119 KGALLITETVVEDLIVKDGKVKGVIAGR-KEGEVLADVVVLAEGAHSLLAQKYGFQKPIP 177

Query: 172 --RKYVAIQQWFA----------EKHPVPFYSCIFDNSITNCY---SWSISKDGYFIFGG 216
                VA+++                P    +       T      ++  +       G 
Sbjct: 178 PQNLAVAVKEVIGLPASVIEDRFNIEPGEGVAIELFGKATAGMVGTAFIYTNQNSLSIGV 237

Query: 217 AYPMKDGQTRFTTLKEKMSAFQFQ------FGKTVKSEKCTVLFPSRWQD--FVCGKDNA 268
              M D   R  +  + + AF+               E    L P            D  
Sbjct: 238 GALMSDLIKRRISPNDLIEAFKNHPAIKPLLRDGEVKEYLAHLIPEGGYKGIPKLYGDGI 297

Query: 269 FLIGEAAGFISASSLEGISYALDSTDILRSVLLKQP 304
            ++G+A   +++   EG + A+ S  +    +++  
Sbjct: 298 VIVGDAGMLVNSIHREGSNLAITSGALAAKAIIRAA 333


>UniRef50_A1VQP8 FAD dependent oxidoreductase n=1 Tax=Polaromonas naphthalenivorans
           CJ2 RepID=A1VQP8_POLNA
          Length = 443

 Score =  114 bits (285), Expect = 5e-24,   Method: Composition-based stats.
 Identities = 78/381 (20%), Positives = 114/381 (29%), Gaps = 54/381 (14%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           FD  IIG GPAGS  A  LA     +AL +K         K CG  LA          G+
Sbjct: 5   FDAIIIGAGPAGSTAAILLARAGWSVALVEKQ---RFPRRKVCGECLAASNLPLLDALGI 61

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQRSYIN-------INRHAFDLWMKSLIPASVE 116
                  A P++  V  +    +   +   +          + R   D  +     AS  
Sbjct: 62  GAGFIASAGPELRQVALMQGQRTFIADLPAAAHGHHAWGRALGRETLDTLLLEQARASGA 121

Query: 117 VYHD---SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGA-----NSMVRRHLYPD 168
           V               D +  +   A      + A  L+ A G+     +    R L   
Sbjct: 122 VVLQPWSVQALGGAAGDHRCGIRSIATRQAATLRAPVLIAAHGSWEPLPSGREDRRLARR 181

Query: 169 HQIRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKD-GYFIFGGAYP-------- 219
                  A +  F     +P    +   S +  Y   +  D G     G           
Sbjct: 182 ASD--LFAFKANFRGATLLPGLLPVL--SFSGGYGGMVLADQGLVTLAGCIRADRLEACR 237

Query: 220 -----MKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEA 274
                +  G+     LK +     F  G   +        P      +   D  F IG A
Sbjct: 238 RAAPGLNAGEAFEIFLKRECRGVAFALGDAQREGAWLASGPIDPGIRLVPGDTLFRIGNA 297

Query: 275 AGFISASSLEGISYALDSTDILRSVLL---------------KQPEKLNTAYWRATRKLR 319
           AG       EG+S A+ S  +L + LL               +  +    A WR     R
Sbjct: 298 AGEAHPIIGEGMSMAMQSAWLLCAQLLHPAVPRSSLSDQRWQRGVQHAYAADWRRHFAPR 357

Query: 320 LKL---FGKIVKSRCLTAPAL 337
           L+L   F  +     + APAL
Sbjct: 358 LRLAAAFAHLAMRPAVAAPAL 378


>UniRef50_B1L3D7 Monooxygenase FAD-binding n=1 Tax=Candidatus Korarchaeum
           cryptofilum OPF8 RepID=B1L3D7_KORCO
          Length = 371

 Score =  113 bits (282), Expect = 1e-23,   Method: Composition-based stats.
 Identities = 57/321 (17%), Positives = 110/321 (34%), Gaps = 36/321 (11%)

Query: 5   DVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           DV ++G G AGS LA  L+     V  ++++      G+   C G+L  DA R  +    
Sbjct: 4   DVLVVGGGIAGSTLASILSSRGFDVTIVERR---PRVGYPHHCSGILGFDAIRELVTFSE 60

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDL--WMKSLIPASVEVYHDS 121
              +  I +    S   + +        +     ++R   DL  W +  + +       +
Sbjct: 61  DWVLSEINHATFISPGGLKIGID-----KPLAKVVDRSMMDLETW-EHALSSGARGMLST 114

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWF 181
             + +   ++              I+   +VGADG+ S V R      ++   + +Q+  
Sbjct: 115 PFKGLKSRNEAIV-------KGDTISFDLIVGADGSLSSVARAFGL-RRLETELGLQRRC 166

Query: 182 AEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQF 241
             +    +   I   S    +SW          G           F  + E + + +   
Sbjct: 167 EGRIGDEYAVRILRGS---NFSWIQPWGDCVKVGAIG-------EFGEIMEVIGSCKSPI 216

Query: 242 GKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLL 301
           G      K       R         N  L+G+AAG +   S  G+ +A+ +  IL     
Sbjct: 217 G------KIEGNLIPRRPRKRFYGGNFALVGDAAGQVKPLSRGGVLFAVRAAKILAEEFE 270

Query: 302 KQPEKLNTAYWRATRKLRLKL 322
           +      ++Y R   ++  + 
Sbjct: 271 RGGLSGLSSYGRRWWEINGRE 291


>UniRef50_A0B6Y7 Geranylgeranyl reductase n=1 Tax=Methanosaeta thermophila PT
           RepID=A0B6Y7_METTP
          Length = 381

 Score =  112 bits (281), Expect = 1e-23,   Method: Composition-based stats.
 Identities = 50/355 (14%), Positives = 118/355 (33%), Gaps = 32/355 (9%)

Query: 6   VAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           + ++G GPAGS  A   A     VI ++++ + G+      CGG +   ++   +     
Sbjct: 3   IIVVGAGPAGSTAAETAARLGADVILVERRMEIGS---PVQCGGFIPEASELRDLLPDAV 59

Query: 65  LPVDVIANPQI-----FSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYH 119
           LP  ++  P+        ++ +   +  +  +  +   ++R +FD ++      +     
Sbjct: 60  LPETLVEIPERCILNRTRIQRLYAPSGRSAEFPVAGRCVDRRSFDRYLAHRAARAGAQLI 119

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQ 179
                 +  E    H+  R +G           G    +S +   +    +    + ++ 
Sbjct: 120 VGTEADVRGE--SIHLKGRREGIIDADIIIGADG---PSSRIAEAIGAVQRDEPGICLEY 174

Query: 180 WFAEKHPVPFYSCIFDNS--ITNCYSWSIS-KDGYFIFGGAYPMK--DGQTRFTTLKEKM 234
              +       + ++         Y+W I   D     G         G+     +  + 
Sbjct: 175 EMVDVDIDRDAAEMYFGERWAPGGYAWIIPLGDDIANVGVGVRRSYIRGEIDLPLILRRF 234

Query: 235 SAFQFQFGKTVKSEKCTVLF----PSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYAL 290
                  G+ ++  +   +     PS     +       L G+AAG + A+S  G+  A+
Sbjct: 235 VEEHPHAGRILRKGEIVAVMRGIVPSGGMPEIIQSGRFLLAGDAAGHVMATSGGGVPLAM 294

Query: 291 DSTDILRSVLLKQPEKLNTA-YWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRS 344
            +  I   V        +   Y +   K         + +    +  +R+ + R+
Sbjct: 295 VAGRIAGEVAATHARGGDLNVYTQRIEKE--------LGAPLRGSVIIRRMVDRA 341


>UniRef50_Q2FUA4 Digeranylgeranylglycerophospholipid reductase n=5
           Tax=Methanomicrobiales RepID=GGR_METHJ
          Length = 402

 Score =  112 bits (280), Expect = 2e-23,   Method: Composition-based stats.
 Identities = 56/306 (18%), Positives = 92/306 (30%), Gaps = 20/306 (6%)

Query: 18  LARKLAGK-MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIF 76
            A+  A K   V+  +K+   G       C   +       F +         I    I 
Sbjct: 19  AAKTFAEKGYSVLLTEKRPAIGAPVR---CAEGVGKALMHEFFKPEDRWVAAEIEKANII 75

Query: 77  SVKTVDVAASLTRNYQRSYININRHAFDL---WMKSLIPASVEVYHDS-LCRKIWREDDK 132
           +     +     +        ++R  FD    WM     A  ++   +     I  +   
Sbjct: 76  APDGFKMELEPEKAGAEVGYVLHRKVFDRDLVWM--AAGAGADIQVKTRAVTPIMEDGAV 133

Query: 133 WHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDH--QIRKYVAIQQWFAEKHPVPFY 190
              I    G  Q + A   + ADG  S   R    D    +R+     Q+      +  +
Sbjct: 134 KGAILNQGGIAQEVRAGLTIAADGVESKFARWCGVDTTVPLREMETCAQYLMTGIDIDAH 193

Query: 191 SCIF---DNSITNCYSWSISKDGYFI---FGGAYPMKDGQTRFTTLKEKMSAFQFQFGKT 244
           +  F   +N     Y W   K         G          R      +  A  F  GKT
Sbjct: 194 ATEFYVGNNIAPGGYVWIFPKGDKTANVGIGVGGDRCKPGNRPIDYLNRFVARNFPNGKT 253

Query: 245 VKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQP 304
           ++     V         V   +N  ++G+AA      +  GI  AL +  +   V  K  
Sbjct: 254 IELIAGGVSICQPLPCTV--ANNLMIVGDAARVSDPLTGGGIYAALYTGKLAGDVGSKAI 311

Query: 305 EKLNTA 310
           EK +T+
Sbjct: 312 EKGDTS 317


>UniRef50_D1H2I2 Whole genome shotgun sequence of line PN40024,
           scaffold_0.assembly12x (Fragment) n=3 Tax=rosids
           RepID=D1H2I2_VITVI
          Length = 351

 Score =  112 bits (280), Expect = 2e-23,   Method: Composition-based stats.
 Identities = 44/279 (15%), Positives = 81/279 (29%), Gaps = 51/279 (18%)

Query: 81  VDVAASLTRNYQRSYIN-INRHAFDLWMKSLIPASVEVYHDSLCRKIWREDDKWHVIFRA 139
            D+   +       YI  + R   D +++    AS                         
Sbjct: 51  FDLPLDIIDRRPHEYIGMVRREVLDSYLRERASASGATVDA------------------- 91

Query: 140 DGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEKHPVPFYS------CI 193
                      ++GADGANS V + +         +A Q+          Y        +
Sbjct: 92  -----------VIGADGANSRVAKFIGAGDYDY-AIAFQERIKIPDDKMVYYENLAEMYV 139

Query: 194 FDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVL 253
            D+   + Y W   K  +   G          +   L  ++ A +   G  +   +    
Sbjct: 140 GDDVSPDFYGWVFPKCDHVAVGTGTVTHKSDIKKFQLATRLRAKEKILGGKII--RVEAH 197

Query: 254 FPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKLN----- 308
                           L+G+AAG+++  S EGI +A  S  +    +++  E        
Sbjct: 198 PIPEHPRPRRLAGRVALVGDAAGYVTKCSGEGIYFAAKSGRMCAEAIVEGSENGKRMVDE 257

Query: 309 ---TAYWRATRKLR---LKLFGKIVKSRCLTAPALRKWI 341
                Y     K      K+   + K    + PA   ++
Sbjct: 258 GDLRKYLEKWDKTYWPTYKVLDVLQKVFYRSNPAREAFV 296


>UniRef50_C6XUK6 FAD dependent oxidoreductase n=1 Tax=Pedobacter heparinus DSM 2366
           RepID=C6XUK6_PEDHD
          Length = 378

 Score =  112 bits (279), Expect = 2e-23,   Method: Composition-based stats.
 Identities = 56/355 (15%), Positives = 112/355 (31%), Gaps = 35/355 (9%)

Query: 6   VAIIGLGPAGSALARKL-AGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           + I+G G +G   A  L     +V  ++K          K CG  ++ +           
Sbjct: 11  ILIVGGGLSGLTCALHLLKEGFEVTLIEK----NAYPHHKVCGEYISNEVLPYLQWLDAD 66

Query: 65  LPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLCR 124
            P +++         +      +          ++R A D ++     +           
Sbjct: 67  -PYELLPVAINRLSVSSLSGQIIGCALPLGGFGLSRFALDHFLYQKALSRGCKVIRDRVT 125

Query: 125 KIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDH--QIRKYVAIQQWFA 182
            I    +++ +     G    + A  ++GA G  S + + L      +   ++A++  + 
Sbjct: 126 DIVFNGNEFELSTSHSG---TLKADLVIGAFGKRSALDQQLSRSFIQKKSPWLAVKAHYN 182

Query: 183 EKHPVPFYSCIFDNSITNCYSWSISKDGYFI-FGGAYPMKDGQT--RFTTLKEKMSAFQF 239
              P+        ++    Y    + +   I        +  +        +EK+     
Sbjct: 183 GIIPIDLVQL---HNFAGGYCGVSAIENKQINICYLADYESFKACANLKDFQEKVLYKNP 239

Query: 240 QFGKTVKSEKCTVLFPSRWQDFVCGK-----DNAFLIGEAAGFISASSLEGISYALDSTD 294
           Q  K  +        P         K     D+  +IG+ AG I      G++ A+ S  
Sbjct: 240 QLRKIFEESSPVFDQPLTISQVSFAKKELVCDHILMIGDTAGLIHPLCGNGMAMAIHSAK 299

Query: 295 ILRSVLLK----------QPEKLNTAYWRATRKLRL---KLFGKIVKSRCLTAPA 336
           I   + ++            EKL TA W A  K RL   +    I++   L  P 
Sbjct: 300 ICAELSIQYLNGKLVSRTTLEKLYTATWNANFKNRLLMGRFLSGIIRKDKLFKPL 354


>UniRef50_A2U0Z5 HI0933-like protein n=1 Tax=Polaribacter sp. MED152
           RepID=A2U0Z5_9FLAO
          Length = 368

 Score =  112 bits (279), Expect = 3e-23,   Method: Composition-based stats.
 Identities = 66/337 (19%), Positives = 123/337 (36%), Gaps = 25/337 (7%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M++FDV I+G G AG  LAR+L+  K QV+ LD+K Q     F+             SFI
Sbjct: 1   MKNFDVIIVGAGTAGLMLARELSKSKKQVLVLDRKKQLLEFSFN----------TLASFI 50

Query: 60  -RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPAS-VEV 117
             D   L  +V+A       K    + S+  + +     +++      +   I    V +
Sbjct: 51  NLDEFNLSNNVVAQKI---NKITFHSNSVKSSLKADLYTLDKKKVHEELVETIDRKFVTI 107

Query: 118 YHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLY-PDHQIRKYVA 176
             ++  + I   DD  H     D  ++  +A   V A G N ++ + +     + +    
Sbjct: 108 QLNTNIKSI-ITDDNHHFTSVIDQNKKEYSATIFVDASGTNGVLSKKVGLLPKKTQLATG 166

Query: 177 IQQWFAEKHPVPFYSCIFDNSITNCYSWSIS-KDGYFIFG-GAYP---MKDGQTRFTTLK 231
           ++     K        +        Y W    K+   I G G +    +KD + R   + 
Sbjct: 167 VEYNVKYKGNTKEIFLLIGEMYQGGYGWIFPLKNNRAIIGFGTFDEAIVKDLKNRLHQIL 226

Query: 232 EKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALD 291
           E     +       K E  ++      + FV   +N   +G++   ++    EG  +  +
Sbjct: 227 EIPMIKKLVEKDNDKVEGGSIPITPVIEKFVL--NNLVCVGDSVSQVNPIVGEGYKFIFE 284

Query: 292 STDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVK 328
           S  +    ++   E  +    +    L    F +  K
Sbjct: 285 SAIMANKAIILALESNDLTKLKDYEVLWRNRFSENYK 321


>UniRef50_Q0SFD6 Pentachlorophenol monooxygenase n=6 Tax=Actinomycetales
           RepID=Q0SFD6_RHOSR
          Length = 480

 Score =  112 bits (279), Expect = 3e-23,   Method: Composition-based stats.
 Identities = 62/355 (17%), Positives = 118/355 (33%), Gaps = 16/355 (4%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQ-VIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M+H DV +IG GP G  LA +LA   + V  LDK+    T          +         
Sbjct: 1   MKHIDVVVIGAGPTGCMLAGELAAAGRSVTVLDKRAAPSTLSR----AFGVHARTLELLD 56

Query: 60  RDGL--TLPVDVIANPQIFSVKTVDVA-ASLTRNYQRSYININRHAFDLWMKSLIPASVE 116
             GL   L     A+P +   +   +    L   +    +   R+   L  +       +
Sbjct: 57  ARGLADRLVATGAASPGLKLWRGAALYLGRLRSRFPFVLVTPQRNVDALLEEHARDRGAD 116

Query: 117 VYHDSLCRKIWREDDKWHVI-FRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYV 175
           +        + ++ +   V      G +    A Y VGADGA+S VR  +      +  +
Sbjct: 117 IIRGFTVTGVEQDGNGVRVHGHDNSGRDSTFLATYAVGADGAHSAVRTMIGQPFPGKAVL 176

Query: 176 AIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMS 235
                   +   P  + +  N++ + +++            A+  +        +  +  
Sbjct: 177 RSIMLADVELENPPDNLVTVNAVRDGFAFIAPYGDNLFRVIAWNRRHQVDDTAPVDREEL 236

Query: 236 AFQFQFGKTVKSEKCTVLFPSRW-----QDFVCGKDNAFLIGEAAGFISASSLEGISYAL 290
               +           V + SR+     Q         FL G+AA   S +  +G++  +
Sbjct: 237 RSTIEVAMGTDYGLGDVRWQSRFHCDERQVLQYRTGRVFLAGDAAHVHSPAGGQGMNTGI 296

Query: 291 DSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSR--CLTAPALRKWIMR 343
                L   L    +  + A        R  +   +++S    +    +R WI+R
Sbjct: 297 QDAVNLGWKLAAVLDGADDAVLDTYHSERHPVGRLVLRSSGATMRMMIVRPWILR 351


>UniRef50_A3XIL9 Putative uncharacterized protein n=1 Tax=Leeuwenhoekiella
           blandensis MED217 RepID=A3XIL9_9FLAO
          Length = 374

 Score =  111 bits (278), Expect = 3e-23,   Method: Composition-based stats.
 Identities = 58/355 (16%), Positives = 115/355 (32%), Gaps = 32/355 (9%)

Query: 6   VAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           +A+IG G AG   A  L     QV+  +K+         K CG  L+ +    +   G+ 
Sbjct: 7   IAVIGAGLAGLTAAIHLRKEGFQVMLFEKEE----YPKHKVCGEYLSNEILPYWKHLGID 62

Query: 65  LPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLCR 124
            P+   A        +     SL          I+R   D  +     +          R
Sbjct: 63  -PLKWGAVAIDQLELSAVNGKSLNIKLPLGGFGISRFKLDHHLLEYALSLGCTLISQTVR 121

Query: 125 KIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPD--HQIRKYVAIQQWFA 182
            I   ++ + +  +     Q   A  ++GA G  S +   L          ++A++  FA
Sbjct: 122 DIHFAENTFSISTKEH---QDFEADLVIGAFGKRSNIDFKLDRKFTASKNDWLAVKAHFA 178

Query: 183 EKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAY------PMKDGQTRFTTLKEKMSA 236
            + P    S             S+ ++               P K+ +T    +  +   
Sbjct: 179 AEIPSDQVSLHNFK--GGYCGISMVEERKVNVCYLTRTEAFKPFKNNETFQQQVLCENPN 236

Query: 237 FQFQFGKTVKSEKCTVLFP-SRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDI 295
               F          +      +Q     +++  + G++AG I      G++ A+ S  +
Sbjct: 237 LNDFFAHAQPLFDQPISISQIAFQSKPSVENHMLMCGDSAGLIHPLCGNGMAMAVISAKL 296

Query: 296 LRSVLLKQP---------EKLNTAYWRATRKLRLK---LFGKIVKSRCLTAPALR 338
               +             E+     W+ T   RL+   L  + +++  LT+  ++
Sbjct: 297 ASECISGSARQDWSRTELEQRYDKLWKQTFTNRLRAGNLLQRALQNDALTSTGIQ 351


>UniRef50_C1AA31 Putative oxidoreductase n=1 Tax=Gemmatimonas aurantiaca T-27
           RepID=C1AA31_GEMAT
          Length = 436

 Score =  111 bits (278), Expect = 3e-23,   Method: Composition-based stats.
 Identities = 64/337 (18%), Positives = 107/337 (31%), Gaps = 40/337 (11%)

Query: 22  LAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVD----------VIA 71
               + V  +D+         SKPC   L+P+  R   R G    ++          V+ 
Sbjct: 46  AQAGLSVCLVDR----ARFPRSKPCAEYLSPEGSRILDRMGALADLEQGAATYLTGMVVH 101

Query: 72  NPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLI-PASVEVYHDSLCRKIWRED 130
            P    +     A    R ++   + I R   D  + + +  A V V   +   ++ R+ 
Sbjct: 102 APAGGRIHGEFAAQHAYRGFRDRGLGIRREYLDALLLNRVRAAGVTVMEGARVTQLCRDA 161

Query: 131 DK--WHVIFRADGWE---QHITARYLVGADGANSMVRRHLYPDHQIRK--YVAIQQWFAE 183
           D     V    D      + + A  +VGADG NS+V       H+ R    VA    +  
Sbjct: 162 DGTVNGVELTRDDEPQTLRTVHASLVVGADGLNSVVASRAGLAHRARWPRRVAYVAHYRN 221

Query: 184 KHPVPFYSCIFDNSITNCY---SWSISKDGYFIFGGAYPMKDGQTR---------FTTLK 231
              +     +      N Y   +   + DG  I   A  +     R          TT  
Sbjct: 222 VARMGTLGEMH--VTDNGYVGLAQVGNGDGASITNVALVLPTRTARALRQSPADTLTTWL 279

Query: 232 EKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALD 291
                   +F    +      + P              L G+AA F+   + EGI  AL 
Sbjct: 280 GAHPQLAERFVNAERMTPVRAVGPFASHARRSWAPGVMLTGDAADFLDPFTGEGIYAALA 339

Query: 292 STDIL---RSVLLKQPEKLNTA-YWRATRKLRLKLFG 324
             ++L      ++  P+         +  + R   FG
Sbjct: 340 GGELLAPIAHAVVHAPDARRRRQALMSYEQARRTTFG 376


>UniRef50_A4YEK4 Geranylgeranyl reductase n=12 Tax=Sulfolobaceae RepID=A4YEK4_METS5
          Length = 453

 Score =  111 bits (277), Expect = 4e-23,   Method: Composition-based stats.
 Identities = 77/376 (20%), Positives = 123/376 (32%), Gaps = 37/376 (9%)

Query: 1   MEH--FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSF 58
           M+   +DV IIG G AGS  A  LA K   I L         G  KPCG  ++ +    F
Sbjct: 1   MKQLTYDVLIIGGGFAGSTAAWHLANKGLKILLIDSKPWNRIG-DKPCGDAVSKE---HF 56

Query: 59  IRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAF-DLWMKSLIPASVEV 117
              G+  P       +I  +K      S     +     IN  A+    ++      VEV
Sbjct: 57  DNLGMPYPEGEQLEQKIDGIKLYSPDMSTEWTVKGEGFEINAPAYTQRILREARDRGVEV 116

Query: 118 YHDSLCRKIWREDD---KWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIR-- 172
              +   K   ED       +  R    +  + A+ ++ A G +   R  L  +  +   
Sbjct: 117 MDLTTAMKPILEDGFVKGAVIFDRRKEEQIEVRAKMVIEATGYSRSFRSKLPQEIPVSED 176

Query: 173 -----KYVAIQQ--WFAEKHPVPFYSCIFDN--SITNCYSWSISKD-GYFIFGGAYPMKD 222
                  +A ++  +  E    P Y  IF N  +    Y W   K       G       
Sbjct: 177 MDERDADIAYREVAYTREDIDEPGYLKIFINQTTSPGGYWWYFPKGKDKVNIGLGIQGGM 236

Query: 223 GQTRFTTLKEKM-SAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISAS 281
           G     T  EK    +     +     K   L P+R        +   +IG++    +  
Sbjct: 237 GYPSIYTFYEKYWKEYGADVDRNRMIVKGGALVPTRRPLDTLVWNGIIVIGDSGYTANPV 296

Query: 282 SLEGISYALDSTDILRSVLLKQPEK---LNTAYWRA---------TRKLRLKLFGKIVK- 328
              G   A+ S        L   EK      + W            ++  L+LF + ++ 
Sbjct: 297 HGGGKGSAMISGFCAARATLNSFEKGDFSAQSLWETNLCYNERYGAKQASLELFRRFLQK 356

Query: 329 -SRCLTAPALRKWIMR 343
            S       +RK ++R
Sbjct: 357 LSDDDINYGMRKKVIR 372


>UniRef50_Q6EVQ8 Putative FAD-dependent monooxygenase n=1 Tax=Yersinia
           pseudotuberculosis RepID=Q6EVQ8_YERPS
          Length = 410

 Score =  111 bits (276), Expect = 5e-23,   Method: Composition-based stats.
 Identities = 57/341 (16%), Positives = 115/341 (33%), Gaps = 26/341 (7%)

Query: 4   FDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +DV I+G    G+A +  L    + V  ++K        + K C   + P A     + G
Sbjct: 3   YDVVIVGGSATGAASSILLRKLGLSVRVIEK--LPSASSYKKLCTHFIQPSAVPVLSQLG 60

Query: 63  LTLPVDVIANPQIFSVKT-----VDVAASLTRNYQRSYININRHAFDLWMKSLIPA-SVE 116
           +    +   + +  +        +D       + Q+  +N+ R   D  ++       VE
Sbjct: 61  MAHLAERDYSVRTRATFITPAGIIDPEGFYGTDSQQCALNLERSVLDPALRQQAYECGVE 120

Query: 117 VYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQI--RKY 174
           + +      + R    W +          I  R+L+ ADG  S++ R L    Q      
Sbjct: 121 IGYAERVMGVQRSPQGWQLTVERTEETFSIEGRFLIAADGRMSLLARLLDNPMQSYENHR 180

Query: 175 VAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTT----- 229
                + +          +F +   N  ++            AY  K+   ++       
Sbjct: 181 ATFFAYCSGIEAPADNRSLFAHH-QNGMAFLYPLINGRTLLSAYISKEISQQWQQHDVKA 239

Query: 230 -LKEKMSAFQFQFGKTVKSEKCTVL----FPSRWQDFVCGKDNAFLIGEAAGFISASSLE 284
            L E  +           + +  V+    +P+  +  VC   +   IG+AA  +   S  
Sbjct: 240 SLVEFFAGVPAMPAMNNVTFETQVMGYRDYPNLTRQPVC--QDVAFIGDAAQSLDPMSGV 297

Query: 285 GISYALDSTDILRSVLLKQPEK--LNTAYWRATRKLRLKLF 323
           G S+AL +  +L   +    +   +NT     T + +   +
Sbjct: 298 GCSFALQTAAMLAQSVEVSLQHGVVNTQLALQTYQRQFNEY 338


>UniRef50_A5FR90 FAD dependent oxidoreductase n=5 Tax=Dehalococcoides
           RepID=A5FR90_DEHSB
          Length = 393

 Score =  110 bits (275), Expect = 6e-23,   Method: Composition-based stats.
 Identities = 59/306 (19%), Positives = 111/306 (36%), Gaps = 19/306 (6%)

Query: 5   DVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           DV +IG GP G   A+ LA    +V  L+KK +   +     C G+++ +    +  DG 
Sbjct: 18  DVLVIGAGPVGLHTAKCLAECGYEVRLLEKKPEAAKQV---CCTGIISTECASKYGFDGK 74

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFD-LWMKSLIPASVEVYHDSL 122
            +  +  +   ++S   V     L R+  ++ I ++R +F    ++  I   V       
Sbjct: 75  YI-QNYFSEASVYSP--VGQKLLLKRDTPQA-IMLDRASFQAKLLQQAINCGVRTSFGFQ 130

Query: 123 CRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFA 182
              I   ++   +  +     Q  TA+ +V A G N+ + R             +Q    
Sbjct: 131 ANSIEYIENGLRITTK---EGQSFTAKAVVLAAGYNTALSRATGLGEINNFAYGLQA--E 185

Query: 183 EKHPVPFYSCIFDN-SITNCY-SWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ 240
               +P    +F   +I+  Y  W    +      G    K+    ++ L   +      
Sbjct: 186 VDTSIPANLSLFTGKAISQGYFGWLSPINDCTAKMGLLTRKNPFECWSALHNTLYKQGLI 245

Query: 241 FGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVL 300
             K +      V   +    F    D    +G+ AG +  ++  GI + L   D+  S L
Sbjct: 246 TAKHINYVCRPVPIGNLSASF---GDRVLAVGDFAGQLKPTTGGGIYFGLLCADLAVSCL 302

Query: 301 LKQPEK 306
            K  + 
Sbjct: 303 DKNIKT 308


>UniRef50_B4D801 Tryptophan halogenase n=1 Tax=Chthoniobacter flavus Ellin428
           RepID=B4D801_9BACT
          Length = 430

 Score =  110 bits (275), Expect = 6e-23,   Method: Composition-based stats.
 Identities = 61/325 (18%), Positives = 105/325 (32%), Gaps = 30/325 (9%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
             ++V IIG GPAG+  A  LA K + + + +K +          G  L P    +  R 
Sbjct: 13  NQYEVIIIGAGPAGTTTAALLAEKGRRVLVLEKEKFPRYHV----GESLMPYCWFTLNRL 68

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNY---------QRSYININRHAFDLWMKSLIP 112
           GL   ++ IA  + +SV+ V      +  +           +   + R  FDL +     
Sbjct: 69  GLVEEMNHIAYTKKYSVQFVTQDGRQSAPFYFFQHYDHPSSTTWQVERADFDLMLLKNAR 128

Query: 113 A-SVEVYHDSLCRKIWREDDK--WHVIFRADGWEQH-ITARYLVGADGAN--SMVRRHLY 166
           A   EV   +   ++ +++      V  R +    H   A   V   G    S+ R    
Sbjct: 129 AKGAEVRELTPVTRLLKDESGKVIGVEARDENGATHEFYAPMTVDCSGREQISIARDGWR 188

Query: 167 PDHQIRKYVAIQQWFAEKHPVPFYS---CIFDNSITNCYSWSIS-KDGYFIFGGAYPM-- 220
                   +AI  +F      P                + W I  K+     G       
Sbjct: 189 VKDAKLNKIAIWTYFRGAKRDPGIDEGNTTVAYVEGRGWFWYIPLKNDTVSVGIVAEKDY 248

Query: 221 -----KDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAA 275
                KD         E+ +  +       +  +  V     ++   C  D   L G+A 
Sbjct: 249 LFSESKDPAKIMQREIERNAWIKEHLSMGEQFGEYFVTSEFSYRSKYCAADGLLLAGDAF 308

Query: 276 GFISASSLEGISYALDSTDILRSVL 300
            F+      G+  AL S ++    +
Sbjct: 309 AFLDPVFSSGVFLALKSGEMAADAV 333


>UniRef50_Q11NI5 Possible oxidoreductase n=1 Tax=Cytophaga hutchinsonii ATCC 33406
           RepID=Q11NI5_CYTH3
          Length = 377

 Score =  110 bits (274), Expect = 9e-23,   Method: Composition-based stats.
 Identities = 65/336 (19%), Positives = 115/336 (34%), Gaps = 28/336 (8%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           + +  A+IG G AG +LA +LA   + VI  +K     T  F K CG  ++ ++    + 
Sbjct: 6   KPYKCAVIGGGVAGLSLAIQLADHGLDVIVFEK----NTYPFHKVCGEYISMESWNFLLS 61

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPA-SVEVYH 119
            GL L  ++          + +    L          I+R   D  +  L  A  V V  
Sbjct: 62  LGLPL-TEMHLPHIKQLGISSEKGFMLQAPLALGGFGISRFTLDQQLYFLAKAKGVRVIE 120

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMV--RRHLYPDHQIRKYVAI 177
           +     +  + D+   I  + G     TA  + G+ G  +    +       ++  Y+ +
Sbjct: 121 NCRVTHVTNDADQITCITTSAGI---FTAEIVCGSYGKYTPAFAKNETNSKKEVINYIGV 177

Query: 178 QQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYP---MKDGQTRFTTLKEKM 234
           +  +  K   P       N        S  ++  +          +K        L+E +
Sbjct: 178 K--YHIKTDFPNNKIELHNFEGGYCGISKVENNTYCLCYLSASDQLKQADNDIKILEETI 235

Query: 235 SAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDN-----AFLIGEAAGFISASSLEGISYA 289
                   +     K     P    +    K N      FL+G+AAG I+     G+S  
Sbjct: 236 LFRNKYLKQIFTESKFLFQQPVVTSNVTFHKKNTYVNGIFLVGDAAGSITPLCGNGMSMG 295

Query: 290 LDSTDILRSVLL------KQPEKLNTAYWRATRKLR 319
           L  + IL  +L+       + + L  AY     K  
Sbjct: 296 LRGSFILAQLLISFYKTNSRKKPLIAAYQHEWNKQF 331


>UniRef50_D2BAF5 Monooxygenase, FAD-binding protein n=4 Tax=Actinomycetales
           RepID=D2BAF5_STRRD
          Length = 379

 Score =  110 bits (274), Expect = 9e-23,   Method: Composition-based stats.
 Identities = 68/316 (21%), Positives = 114/316 (36%), Gaps = 41/316 (12%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSF- 58
           M+  DV ++G G AG   AR LA  ++ V+ +D++    T   +    G+        F 
Sbjct: 1   MQTVDVLVVGAGLAGLRTARLLARRELNVMVVDRRRSLSTGIRT---TGIFVRRTLDDFD 57

Query: 59  ---------IRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKS 109
                    IRD L  P    A  ++ S +     A +   Y++++            ++
Sbjct: 58  VPDHLLGPGIRDVLLYPPSRRAPIRLTSDRDEYRVADMAAVYEQAH------------RA 105

Query: 110 LIPASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDH 169
              A   V                 + F      + +TAR++VGADGA S V R L  D 
Sbjct: 106 AESAGARVLLGVRYVD-------ASMGFVRFAGAEPVTARFIVGADGARSRVARDLGLDV 158

Query: 170 QIRKYVAIQQWF--AEKHPVPFYSCIFDNSITNCY-SWSISKDGYFIFGGAYPMKDGQTR 226
             R  V  +  +  A     P + C+ D  +   Y  W I    +   G A      +T 
Sbjct: 159 NRRFLVGAEIVYPIASGTATPAFHCVLDPRVAPGYLGWVIDDGRHAHVGVAGYPNVMRTG 218

Query: 227 FTTLKEKMSAFQFQF---GKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSL 283
              L E  +A           V+     +      +   C      L+G+AAG +S  + 
Sbjct: 219 IRHLLEAFAADAPGSTPPAGPVERRGGPIPVGGVLRRLACPAG--LLVGDAAGAVSPLTA 276

Query: 284 EGISYALDSTDILRSV 299
            G+   L  +++  +V
Sbjct: 277 GGLDPCLRMSELAAAV 292


>UniRef50_A3DPJ1 Geranylgeranyl reductase n=2 Tax=Desulfurococcaceae
           RepID=A3DPJ1_STAMF
          Length = 458

 Score =  110 bits (274), Expect = 1e-22,   Method: Composition-based stats.
 Identities = 60/324 (18%), Positives = 107/324 (33%), Gaps = 28/324 (8%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
            +DV ++G G AG   A  LA K   +A+ +       G  K CG  +     +      
Sbjct: 2   KYDVIVVGAGVAGLNAAFVLASKGFNVAIIESKPRSRIG-DKTCGDAIGVHHFKELGWY- 59

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSL 122
              P +   + +   VK    +   +       +++NR  F  W+      +  V  D  
Sbjct: 60  ---PPEETIDHRYKGVKIYSPSEKYSIIVSGEGVSVNRLKFGQWLLKRAEDNGAVLLDKH 116

Query: 123 CRKIWREDDK----WHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKY---- 174
                + +D       V        + + A   +   GA   +R  L  +  I +     
Sbjct: 117 VLLGVKFNDNGIQSIKVKELGKPGLKELVADAFIDTSGAKPALRSKLPLEWPISERPYMT 176

Query: 175 ---VAIQQWFAEKHPVP----FYSCIFDNSI--TNCYSWSISKDGY---FIFGGAYPMKD 222
              +A ++      PV      Y+ I+ N+I     Y W   K+        G       
Sbjct: 177 DYNIAYREVLEINEPVNDEDVDYAVIYLNTIIAPGGYWWFFPKNPSGKIVNVGLGVVWGV 236

Query: 223 GQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASS 282
                     K    +F+ GK + +    V  P+R         N  + G+AA  ++   
Sbjct: 237 DDYNPRHNYNKYLKPRFK-GKLLHAGGGMV--PTRRPLPTLVWRNVGVAGDAAYTVNPVH 293

Query: 283 LEGISYALDSTDILRSVLLKQPEK 306
             GI  +L ++ I+   +    EK
Sbjct: 294 GGGIGSSLQASAIVAKYIGDALEK 317


>UniRef50_A8ABI3 Geranylgeranyl reductase n=1 Tax=Ignicoccus hospitalis KIN4/I
           RepID=A8ABI3_IGNH4
          Length = 444

 Score =  109 bits (272), Expect = 1e-22,   Method: Composition-based stats.
 Identities = 50/293 (17%), Positives = 93/293 (31%), Gaps = 20/293 (6%)

Query: 3   HFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            +D  ++G G  G   A+ LA    +V+ ++ K +   E  +K CG  ++ +    F + 
Sbjct: 2   EYDAVVVGAGTTGLVAAKFLAEAGYKVLVVELKAE--EEVGTKVCGDAISKE---YFEKI 56

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLI-PASVEVYHD 120
            +  P +   +  I   K                  +NR  F  W+ ++   A  E    
Sbjct: 57  PIGNPPEEAVDGNIVGAKIYSPDEETVWTVPGEGYMLNRKKFGEWLYNMAKEAGAEFSFK 116

Query: 121 SLCRK-IWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHL-------YPDHQIR 172
           +     + +++    +  R DG  + + AR +V A G   +VRR L        P     
Sbjct: 117 TRALGPVVKDNKVVGLTVRKDGKVETVRARLVVDASGVAYVVRRALPKSWPVAEPLDPKD 176

Query: 173 KYVAIQQWFAEKHPVPFYSCIF----DNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFT 228
             VA ++      P+     I            Y W     G         ++ G     
Sbjct: 177 TAVAYREIRRITTPLEDDKYIRIYVGQQKAPGGYWWLFPYRGGARVNLGLGVQGGVGHKD 236

Query: 229 TLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISAS 281
            +         +F           + P+R              G+AA  ++  
Sbjct: 237 PMWYFHEYLAPRF-PGEVEHAGGGVVPTRRPLDTMVAHGFATAGDAAYQVNPI 288


>UniRef50_Q2NGA2 Predicted dehydrogenase n=1 Tax=Methanosphaera stadtmanae DSM 3091
           RepID=Q2NGA2_METST
          Length = 382

 Score =  109 bits (272), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 62/305 (20%), Positives = 112/305 (36%), Gaps = 18/305 (5%)

Query: 5   DVAIIGLGPAGSALARK-LAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           D+ I+G GP+G   A++      +V+ LDK +      +            + S  + G+
Sbjct: 6   DILIVGGGPSGLLAAKEGCFNNNKVVLLDKDNTDTYNEYI----------TKTSLRQIGI 55

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNY----QRSYININRHAFDLWMKSLIPASVEVYH 119
                 I N     +        +  N           I+++ F   ++  I  +VE+  
Sbjct: 56  KEDDSWIVNQTNGFILEAMDEKLVLDNTTTVQPEEAYIIDKNKFIKALRDDIKENVEII- 114

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQ 179
           D+  + I    DK  V       +  IT + L+ A G +  + + +  D++      I Q
Sbjct: 115 DTEAKTITHIKDKVVVEAENSTGKYTITTKILIIASGYHDNLIKQVGMDYKNMDTQHILQ 174

Query: 180 WFAEKHPVPFYSCIF-DNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQ 238
           +  E   +   + I+  N I N    SI          +  MKD       L   + +  
Sbjct: 175 YELENTHLKTNNIIYSFNEIENNALISILPGKNNTASISITMKDDANITEILDSYIKSNN 234

Query: 239 FQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRS 298
                 +   K + + PS         DN  L G +AGF++  +++G+S AL+S      
Sbjct: 235 ELRDSNIIC-KTSHILPSNGIIPKRVADNIILCGNSAGFVNPLTMKGLSGALESGTYAGV 293

Query: 299 VLLKQ 303
           V  K 
Sbjct: 294 VAAKH 298


>UniRef50_D1C5T7 Monooxygenase FAD-binding protein n=2 Tax=Thermomicrobia (class)
           RepID=D1C5T7_SPHTD
          Length = 415

 Score =  109 bits (271), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 63/321 (19%), Positives = 110/321 (34%), Gaps = 26/321 (8%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           +D  I+G   AGS  A  LA +   I L  +        S     L   D+  +F R G+
Sbjct: 2   YDAIIVGARIAGSTTALLLAQRGYSILLLDRD---RFPSSTLSTHLFFTDSLSAFERIGV 58

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQRSY-ININRHAFDLWMKSLIPAS--VEVYHD 120
              V  I  P++  ++   V A       R + + I R   D  +     A   +E++  
Sbjct: 59  LDRVLAIDAPRLKRLRFPYVDAPFAEVDGRDFALCIRREPLDAILVEAAGAHPEIELHTG 118

Query: 121 SLCRKIWRE-DDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQ 179
           +    + RE +    V ++  G E    AR+++GADG +S+V R +              
Sbjct: 119 ARVTGLLREGERVIGVRYQEAGQEHEARARFVIGADGRHSLVAREVGATAYEDFPPMFAW 178

Query: 180 WFAEKHPVPFYSCIFDNSITNCY---------SWSISKDGYFIFGG---------AYPMK 221
           ++     VP        ++   Y         S+    D      G         A+   
Sbjct: 179 YYGYFRGVPLDDPPSAFAVRGTYPEIGAEYAASFIFPCDDGLTLVGFGVQASAFDAFRRN 238

Query: 222 DGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISAS 281
             +  F  L     A +      ++           +     G   A L+G+A       
Sbjct: 239 HREHFFGGLARIPEAMERIGDSQLEGPIVGTGDLPNFLRVPVGPGWA-LVGDAGCHKDPH 297

Query: 282 SLEGISYALDSTDILRSVLLK 302
           S++G+  A+ S  +L   L +
Sbjct: 298 SVQGMGDAVRSAQLLVESLDR 318


>UniRef50_C0G122 Geranylgeranyl reductase n=1 Tax=Natrialba magadii ATCC 43099
           RepID=C0G122_NATMA
          Length = 495

 Score =  109 bits (271), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 62/353 (17%), Positives = 114/353 (32%), Gaps = 42/353 (11%)

Query: 2   EHFDVAIIGLGPAGS-ALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
             +DV ++G G AG  A A   A  + V+ L++K     +G    CG  +   + R    
Sbjct: 4   NQYDVIVVGGGIAGCFAAATAAAEGIDVVQLERK--PREQGGFIACGDAI--KSPRDPQN 59

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASL---------TRNYQRSYININRHAFD-LWMKSL 110
               + +D IA+ +   V                     Y+ S   ++R+ F    ++  
Sbjct: 60  YPGPIDMDAIADDEAVLVDNNIDQIEYWDEELGVRKVLPYKDSSNVVDRYEFGQRLLEQA 119

Query: 111 IPASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDH- 169
               VE ++D++  ++ +      V    DG         L+ A GA S+++  +  +  
Sbjct: 120 ADCGVEQHYDTVVNEVTQNGQVTGVKAVRDGEPVTYECDVLIDAAGAQSILQDMVSFEDL 179

Query: 170 --------QIRKYV----AIQQWFAEKHPVPFYSCIFDNSITN-CYSWSISK-DGYFIFG 215
                   ++  Y     A ++    + PV +++ I    +    Y W   +       G
Sbjct: 180 DTPGEPTFEVPHYTHFGSAYREIIETEQPVEYHNAIVGKPLEEMGYIWYFPRTPTQINVG 239

Query: 216 GAYPMKDGQTRFTT-LKEKMS--------AFQFQFGKTVKSEKCTVLFPSRWQDFVCGKD 266
             + M          L+  +             +FG T K      L          G  
Sbjct: 240 LGFQMNKEPIPLADRLRRDIEHRHEYQGATVAERFGNTNKLGAAIALRRPLDSMVAPG-- 297

Query: 267 NAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLR 319
                G AAG     + +GI  A  S         +  E  +T+        R
Sbjct: 298 -YLATGGAAGTTHPITGKGIRGAAYSGYSAGRAATQAIEDGDTSEAGLWEHNR 349


>UniRef50_B3PIM4 Putative uncharacterized protein n=1 Tax=Cellvibrio japonicus
           Ueda107 RepID=B3PIM4_CELJU
          Length = 438

 Score =  109 bits (271), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 68/351 (19%), Positives = 112/351 (31%), Gaps = 35/351 (9%)

Query: 3   HFDVAIIGLGPAGSALA-RKLAGKMQVIALDKKHQCGTEGFSKPCG----GLLAPDAQRS 57
             DV +IG GPAG   A R     ++V  +++K     + F   C     G   P  Q+ 
Sbjct: 13  QVDVLVIGSGPAGCTTALRYAQEGLRVALVERKR--AMDSFKPVCTHFIQGCATPVLQKM 70

Query: 58  FIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPAS--V 115
            + D L     V  N      +   +   +  + Q     I R   D  ++        +
Sbjct: 71  GVLDTLKAAGAV-RNDIHIWTRYGWIKPEVDADAQHHGYVIRRSTLDPILRDAAQNHPNI 129

Query: 116 EVYHDSLCRKIWREDDKWHVIFRADGWEQH----ITARYLVGADGANSMVR-----RHLY 166
           E+Y      K+   + +  +    D  EQ     + A+  VGADG NS V      R   
Sbjct: 130 ELYMGWRLVKLIENEQQDIIGAEIDSAEQKRTLRLAAQLTVGADGRNSAVAEGLPIRIHS 189

Query: 167 PDHQIRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTR 226
            +++   +V+  +              +   I    ++    DG          +D   +
Sbjct: 190 TENKRTFFVSYYENLQLTSGAISQLWFWKKDI----AYCFPSDGGVTLMCLGIHEDNMAQ 245

Query: 227 FTTLKE-------KMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFIS 279
           F    E       K            +    T       Q     +    L+G+A   I 
Sbjct: 246 FKDNPEQAFHDYFKQLTDGPAMDMAQRVAPVTKGKHMHTQRRYHDRSGVALVGDALLGID 305

Query: 280 ASSLEGISYALDSTDILRSVLL-----KQPEKLNTAYWRATRKLRLKLFGK 325
             +  GI +A+   D L    L     + P  L  A  R T+    +L G 
Sbjct: 306 PFAGTGIGWAIQGGDWLVEETLPALKAQSPTHLRQALARYTQLHETRLRGH 356


>UniRef50_A0B730 Geranylgeranyl reductase n=1 Tax=Methanosaeta thermophila PT
           RepID=A0B730_METTP
          Length = 386

 Score =  108 bits (270), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 59/344 (17%), Positives = 114/344 (33%), Gaps = 21/344 (6%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M+ +DVA+IG GPAG   A+  +    + I L++    G   +   C GLL   A  +  
Sbjct: 1   MDIYDVAVIGAGPAGLMAAKHASMCGARTIVLEEHMAIG---YPVQCAGLLGISALEASE 57

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRS-YININRHAFDLWM-KSLIPASVEV 117
                     + NP   +V      + L+          ++R  FD  M  + +   VE+
Sbjct: 58  IQTEGF----LINPFKGAVFVSPNGSRLSFKSPNVRAWAVDRRLFDRSMALAAVHHGVEI 113

Query: 118 YHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGAN-SMVRRHLYPDHQIRKYVA 176
             ++  R + R  D   +       ++ I AR ++ A+G   S+ RR   P  +     A
Sbjct: 114 TLNAHVRSLRRLGDLMILHH----GDKEIAARAVISAEGVRASIARRSGIPPPKRLLSGA 169

Query: 177 IQQWFAEKHPVPFYSCIFDNSITNC-YSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMS 235
             +   +   +          I    ++W I             +   +     LK+ +S
Sbjct: 170 QVEVPFDVDDIESVEVHLGKDIAPGLFAWVIP---ISRSSARIGLCATERACHYLKKFLS 226

Query: 236 AFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDI 295
           + + +           V             D   ++G+AA  +  +S  G+   +    I
Sbjct: 227 SDRIRNRILGSPVALVVGGLPLGPPDRTVADGLLVVGDAAAHVKPTSGGGVYPGIVCGRI 286

Query: 296 LRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRK 339
              +  +              +      G+ +         LR+
Sbjct: 287 AGRIAAEHVLTGGQ--LERYEREWRSAIGREISLGMRVNDILRR 328


>UniRef50_A8MD19 Monooxygenase FAD-binding n=1 Tax=Caldivirga maquilingensis IC-167
           RepID=A8MD19_CALMQ
          Length = 401

 Score =  108 bits (270), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 71/353 (20%), Positives = 117/353 (33%), Gaps = 29/353 (8%)

Query: 5   DVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLA---------PDAQ 55
           ++ IIG GPAGS LA ++     V  LDKK           CG ++          P   
Sbjct: 7   ELLIIGGGPAGSFLASEV-NLGDVTLLDKKKI---NYGPVVCGEMMPKAELLVDYLPSEL 62

Query: 56  RSFIRDGL--TLPVDVIANPQIFSVKTVDVAASLT--RNYQRSYININRHAF-DLWMKSL 110
            S I   L  ++   +I N        + V  ++    +       +N+       +   
Sbjct: 63  MSMIEYTLYKSIRRSIIVNHIKTLRVLIRVKGTIIDLGSINFPAYIVNKGLMISRIINDA 122

Query: 111 IPASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLY--PD 168
               V V   S      +  D +      +  E ++    L GADG  S+VR      P 
Sbjct: 123 ANKGVRVNFSSTVTGCIKHGDGFKCRVMDNDGEHYVETHLLAGADGYPSVVRELANNPPF 182

Query: 169 HQIRKYVAIQQWFAEKHPVPFYSCIFDNSI--TNCYSWSIS-KDGYFIFGGAYPMKDGQT 225
           + +   VA  Q           + +  + I     Y+W     DG    G      D   
Sbjct: 183 NPMDTAVATSQRAMGWGGSLDEAVVIMDPILAPGGYAWVFPRGDGSSNVGLGIRGYDAWV 242

Query: 226 RFTTLKEKMSAFQFQFGKTVKSEKCTV-LFPSRWQDFVCGKDNAFLIGEAAGFISASSLE 284
           +        S F              +   P          +  +L+G+AAG + +++  
Sbjct: 243 KGINPVNLHSEFLKSLNLKPTQRSILLKTIPVGELGASIEGNGVYLLGDAAGTVVSTNGA 302

Query: 285 GISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPAL 337
           GI+ A+ S  IL  VL +       +Y    R++       + + R L  P L
Sbjct: 303 GINTAMVSGLILAKVLKEGL-----SYGTEMRRVLGSFLSDVKRLRELADPML 350


>UniRef50_Q4MV03 Geranylgeranyl hydrogenase BchP, putative n=12 Tax=Bacillus cereus
           group RepID=Q4MV03_BACCE
          Length = 409

 Score =  108 bits (270), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 64/354 (18%), Positives = 118/354 (33%), Gaps = 42/354 (11%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           + +DV I G   AGS LA  LA     V+ +D+                   +       
Sbjct: 3   KTYDVIITGARCAGSTLAIYLAKAGFHVLLVDR----ANFPRDTLLTHTFFNNTVALLRE 58

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSY-----ININRHAFDLWMKSLI--PA 113
            G+   +     P +  +K       +       Y       I R   D  +        
Sbjct: 59  TGVLDKLLETKVPPVRDIKFQFEDTVIEGLIPEVYGEESCYCIRRTYLDHILLEQAKSQM 118

Query: 114 SVEVYHDSLCRKIWREDDKWHVI--FRADGWEQHITARYLVGADGANSMVRRHLYPDHQI 171
           +V V        + R+D+    +     D  +Q   AR +VGADG +S++R+ +  + +I
Sbjct: 119 NVTVLEGFRVTDVIRDDETVIGVKGLDGDNEKQEFLARLVVGADGRSSIIRKLVKSELKI 178

Query: 172 RKYVAIQQWFAEKHPV--PFYSCIFDNSITNCYSWSISK-DGYFIFGGAYPMKDGQTRFT 228
                +  +F                  I +  +      D  ++  G +P+++ +    
Sbjct: 179 SIPATVGIYFGYFSGFRHDNVPKFEVYKIKDNTAILFPTNDDLYVIVGIFPLENKEL-IE 237

Query: 229 TLKEKMSAFQFQF----------------GKTVKSEKCTVLFPSRWQDFVCGKDNAFLIG 272
            LK    +    F                 + V+  K  + + + W     GK  A L+G
Sbjct: 238 RLKLNPESCLRNFFTDNFPNTTIGARLKNAELVEPVKGILGYDNYWY-KGMGKGWA-LVG 295

Query: 273 EAAGFISASSLEGISYALDSTDILRSVLLK------QPEKLNTAYWRATRKLRL 320
           +A  F      +GI  A+    IL ++L K      Q  +++  Y +A     +
Sbjct: 296 DAVCFKDPGMAQGIHDAICGARILSNILSKYKGQSDQSNQMSEEYQKAIEDEFM 349


>UniRef50_A4JL31 Monooxygenase, FAD-binding n=3 Tax=Burkholderia cepacia complex
           RepID=A4JL31_BURVG
          Length = 461

 Score =  108 bits (270), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 70/370 (18%), Positives = 121/370 (32%), Gaps = 27/370 (7%)

Query: 5   DVAIIGLGPAGSALARKLAGKMQ-VIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           D  IIG   AG+ LA  LA   + V+A+D  H    +  S      ++P          L
Sbjct: 3   DTLIIGARCAGATLAIHLARAGKRVLAIDANHLPSDQPLS---THWISPYGMALLDELEL 59

Query: 64  TLPVDVIANPQ-IFSVKTVDVAASLTRNYQRSYININRHAFD-LWMKSLIPASVEVYHDS 121
              V   A P         DV   +            R   D L ++    +  EV   +
Sbjct: 60  GDKVRRFAPPVPSMMYGNDDVTGRVEYPVGGRCSCPRRMDLDALLLEEARASGAEVRART 119

Query: 122 LCRKIWREDDKWH-VIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW 180
               + R+ ++    +   DG  + I AR +VGADG +S     +  + +   Y   +  
Sbjct: 120 RLVGLLRDGERVTGAVVEHDGVREEIRARIVVGADGPHSTTAELVGAE-EYHGYDCPRAM 178

Query: 181 FAEKHPVPFYSCIFDN--------SITNCYSWSISKD-GYFIFGGAYPMKDGQTRFTTLK 231
           +    P P +              +  +   +    +    + G A+P            
Sbjct: 179 YWAYWPRPDWFDTDPRYLGGAMNCTFGDDIVFVFPTNRDLLLIGVAFPKTQLPQWKGRAL 238

Query: 232 EKM---SAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKD---NAFLIGEAAGFISASSLEG 285
           EK+             +  E  + +  +    F   +       L+G+A  F+  S   G
Sbjct: 239 EKLTETLKGNRHTAPLITGEPVSKVLGALKLRFFFRQAAGPGWALVGDAGLFMDPSPGFG 298

Query: 286 ISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCL--TAPALRKWIMR 343
           I+ AL     L   +++  ++    YWR      + LF        L    P  R  I+ 
Sbjct: 299 ITDALRDARALGQAIVEDDDRALECYWRQRDATSIDLFEYSRGRGALGHNNPLSR--ILF 356

Query: 344 SGVAHIPQLK 353
             +   P L+
Sbjct: 357 GKLTADPVLQ 366


>UniRef50_O28636 Bacteriochlorophyll synthase, 43 kDa subunit (ChlP-3) n=2
           Tax=Archaeoglobaceae RepID=O28636_ARCFU
          Length = 394

 Score =  108 bits (270), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 59/335 (17%), Positives = 111/335 (33%), Gaps = 35/335 (10%)

Query: 5   DVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLL-APDAQRSFIRDG- 62
           DV + G+G AG+   R L   + V+ +DK+ + G   +   CG ++      ++ + D  
Sbjct: 17  DVVVAGVGIAGAFALRALDKSLDVVGIDKREKLG---YPVECGEIIPTKREMKALLPDLD 73

Query: 63  ----LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVY 118
                 +P    +N        +    +   +++  +  + R   D  ++++   S    
Sbjct: 74  DYSLFDIPKRFESNLTKEVHFVLPNGKTFEIDFE--FHVVRR---DEMIQTIAEESSHKL 128

Query: 119 HDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQ 178
              L ++I    D   V+      E  + A   V +DG NS + R L          A Q
Sbjct: 129 L--LNKRIKAFRDGKIVL-----EEGEVGAEVYVASDGPNSKIARSLGMPKP-ELSPAKQ 180

Query: 179 QWFAEKHPVPFYSCIF--DNSITNCYSWSISKD-GYFIFGGAYPMKDGQTRFTTLKEKMS 235
                         ++         Y+W I K  G    G  +   +  +R  T+ + + 
Sbjct: 181 YVMKGVECNEDVVYMYIGRKISPGAYAWIIPKGKGVANVGIGF-RPEYASRGDTIVKALD 239

Query: 236 AFQFQF-------GKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISY 288
            F  ++                  + P         K N    G+AA  + +    GI  
Sbjct: 240 HFVREYPYSSPFLKDAEVVSSIGAVVPIDRPFESAVKGNVLFAGDAASMVISHVGGGIPT 299

Query: 289 ALDSTDILRSVLLK--QPEKLNTAYWRATRKLRLK 321
           A+ + D    V+      E     Y    +K   K
Sbjct: 300 AMVAGDAAARVINGFFNGENDLQLYDSLWKKYLYK 334


>UniRef50_Q4V217 Possible monooxygenase n=1 Tax=Bacillus cereus E33L
           RepID=Q4V217_BACCZ
          Length = 404

 Score =  108 bits (270), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 64/326 (19%), Positives = 118/326 (36%), Gaps = 37/326 (11%)

Query: 5   DVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           DV I+G GP G  L+  LA    + + L++  +   E      G    P   + F + GL
Sbjct: 4   DVVIVGAGPGGCFLSYLLARSGVKTVLLERHERLDREFR----GYFFQPLVLKFFEQTGL 59

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTR----NYQRSY---ININRHAFDLWMKSLIPA--S 114
              V  I + ++ +   +D   +L         + Y   + +++     ++        +
Sbjct: 60  LNDVLQIKHEKVDAFHFIDHGKTLFSVRFDELPKPYDYGLIMSQPLLLQFLIDQALQYDN 119

Query: 115 VEVYHDSLCRKIWREDDKW-HVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRK 173
              +  ++ ++  +E++K   +  +    E  I +R +VGADG  S +R+          
Sbjct: 120 FSYFSGTIAKEFIKEENKIAGIKAKQKKQEIIIESRLVVGADGRYSTIRKLAGIPLDKES 179

Query: 174 YVAIQQWFAEKHPVP----FYSCIFDNSITNCY---------SWSISKDGYFIF---GGA 217
           +     WF            +  I D  +              W I K  Y      G  
Sbjct: 180 HQFDFVWFDMPALEGKRYLPHIQIEDEGMLIYIPKGSGVVQVGWVIRKGTYPDLRKKGIE 239

Query: 218 YPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGF 277
           Y  K        L++++S +   F +      C+VL           +D   LIG+AA  
Sbjct: 240 YFQKQLIAVDPELEQQLSVYLHDFKQ------CSVLDIQVATSNQWVQDGLMLIGDAAHI 293

Query: 278 ISASSLEGISYALDSTDILRSVLLKQ 303
            S  S +G S A+    +   V++K 
Sbjct: 294 ASPFSGQGNSLAIQDAVVAHDVIMKA 319


>UniRef50_B4AWE1 Monooxygenase FAD-binding n=1 Tax=Cyanothece sp. PCC 7822
           RepID=B4AWE1_9CHRO
          Length = 432

 Score =  108 bits (269), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 59/333 (17%), Positives = 111/333 (33%), Gaps = 32/333 (9%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           +++AIIG GPAG++LA  LA   + +A+ +K            G  L P         G+
Sbjct: 3   YEIAIIGGGPAGASLATYLARAGKSVAIFEKSDFPRFHI----GESLLPATMPILQDLGV 58

Query: 64  TLPVD-VIANPQIFSVKTVDVAAS-------LTRNYQ--RSYININRHAFDLWMKSLIPA 113
              +     N         D            T +++  R    + R  FD  +      
Sbjct: 59  YERMRSTFLNKPGGCWYYDDTPVMSDFAKCRETASFKDFRHAFMVERGEFDRILLDNARD 118

Query: 114 -SVEVYHDSLCRK-IWRED--DKWHVIFRADGWEQHITARYLVGADGANSMVR--RHLYP 167
             V V+   L R+ IW  +      V        + I    +    G  S++   R+L  
Sbjct: 119 HGVRVFQHHLVREAIWEGERMTGLQVKDLQTMEGKSIRTEMVFDCSGYRSVIASQRNLRK 178

Query: 168 DHQIRKYVAIQQWFAEKHPVPF--YSCIFDNSITNCYSWSISKD-GYFIFGGAYPMKDGQ 224
            ++++K +AI   +  +                 + + W I  D      G    + + +
Sbjct: 179 PNRLKK-MAIFAHYRAEALEERLKQGWFVGQMFYDGWLWLIPIDKDRISIGVVTTLDNYK 237

Query: 225 TRFTTLKEKMSAFQFQFGKTVKSEKCTVLF---PSRWQDFVCGKDNAF-----LIGEAAG 276
               + ++ +  +      T K     +        + +     +  F     L+G+AA 
Sbjct: 238 KASISPEQFLDHYIRTLSLTRKGLGKNIERVSDIYLYGNLGYSSERIFGDRWALVGDAAV 297

Query: 277 FISASSLEGISYALDSTDILRSVLLKQPEKLNT 309
           FI      G+  A+DS   +  V L+      +
Sbjct: 298 FIDPCYSSGVHLAMDSAREIARVYLEHGYDARS 330


>UniRef50_C6VXB5 FAD dependent oxidoreductase n=1 Tax=Dyadobacter fermentans DSM
           18053 RepID=C6VXB5_DYAFD
          Length = 379

 Score =  108 bits (269), Expect = 4e-22,   Method: Composition-based stats.
 Identities = 67/350 (19%), Positives = 116/350 (33%), Gaps = 33/350 (9%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           EHF+ AI+G G AG  LA +LA   + V+  +K        F K CG  ++ ++      
Sbjct: 6   EHFECAIVGGGLAGLCLAIQLADRGISVVLFEK----NRFPFHKVCGEYISMESWPFLES 61

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLI-PASVEVYH 119
            GL L  ++          + +    L          I+R   D  +  L     V V  
Sbjct: 62  LGLPL-AEMELPKISRLGISSERGFVLNHRLGMGGFGISRFTLDHALFELAVRKGVSVMQ 120

Query: 120 DSLCRKIWRE-DDKWHVIFRADGWEQHITARYLVGADGANSM--VRRHLYPDHQIRKYVA 176
           +     +    DD + V   A        A+ + G+ G      +R H     +I     
Sbjct: 121 ECRVIDVQGNADDGFQVRTSAGD----FQAQVVCGSYGKYGPQFIRLHENDALKIDSQNY 176

Query: 177 IQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSA 236
           I   +  K   P       N        S     ++        ++       +K+   A
Sbjct: 177 IGVKYHIKTDFPTDRIELHNFTGGYCGISKVDQDWYCLCYLTTARNLIANGKDVKQMEEA 236

Query: 237 ------FQFQFGKTVKSEKCTVLFPS--RWQDFVCGKDNAFLIGEAAGFISASSLEGISY 288
                 F   +    +      L  S  ++       +  FL+G+AAG I+     G+S 
Sbjct: 237 VLFKSPFLKHYFTHSEFVNAQPLVISNVQFSKKQTHSNGIFLLGDAAGSITPLCGNGMSM 296

Query: 289 ALDSTDILRSVL----------LKQPEKLNTAYWRATRKLRLKLFGKIVK 328
            + ++ +L   L           K  E  ++A W A    R++    + K
Sbjct: 297 GMRASKLLAEQLYLFFDGKQTHDKASEHYHSA-WNAAFGTRVRAGYHLQK 345


>UniRef50_C6WHE7 Monooxygenase FAD-binding n=2 Tax=Actinomycetales
           RepID=C6WHE7_ACTMD
          Length = 429

 Score =  108 bits (269), Expect = 4e-22,   Method: Composition-based stats.
 Identities = 56/328 (17%), Positives = 102/328 (31%), Gaps = 22/328 (6%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDA---QRSFI 59
            +DV ++G   AG A A + +     +AL  +         + C   + P A        
Sbjct: 21  SWDVVVVGGSIAGCATAIRFSRMGHRVALLDRKTMDDGHHKRLCTHFIQPHAVPLLAGLG 80

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRS----YININRHAFDLWMKSLIPA-S 114
            D L  P   +    +F      V                +N+ R   D  ++       
Sbjct: 81  LDHLYGPEWSVRTKAVFVTPGGVVEGPGLSYDPDQPGAHALNLERRVLDPALRESARRHG 140

Query: 115 VEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRK- 173
           VE    +    I R+   W +    D   +   AR +V ADG  S + + L    + R  
Sbjct: 141 VEYLDGTGVESIGRDGSDWFLDTDGDRGPRRFRARLVVAADGRRSRLAKELGNPAESRPN 200

Query: 174 -YVAIQQWFAEKHPVPFYSCIF-DNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLK 231
              A+  +F+          +F  +      ++ +      +    +  K     +    
Sbjct: 201 ERAALFGYFSGITTRADQRSVFVMHERDLACAYPLPGGRTQLV--LFADKARVEGWGGAD 258

Query: 232 EKMSAFQFQFGKTVKSEKCTVLFPS----RWQDFV-----CGKDNAFLIGEAAGFISASS 282
            +M  F   F     +       P      + D+         D+   +G+AA  +   S
Sbjct: 259 NRMREFLAYFDGLPDAPSTAGAVPEGGLLGYADYPSLLREPVVDSVPFVGDAALSLDPMS 318

Query: 283 LEGISYALDSTDILRSVLLKQPEKLNTA 310
             G  +AL S D+L S    +    +  
Sbjct: 319 GVGCGFALVSADLLASSFADRSLSEDDR 346


>UniRef50_Q0R4P7 ChlB4 n=8 Tax=Bacteria RepID=Q0R4P7_STRAT
          Length = 449

 Score =  107 bits (268), Expect = 4e-22,   Method: Composition-based stats.
 Identities = 68/367 (18%), Positives = 116/367 (31%), Gaps = 53/367 (14%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
            FD AI+G GPAGSA+A  LA     +A+ +             G  L P         G
Sbjct: 4   DFDAAIVGGGPAGSAMASYLAEAGLSVAVFESEMFPRPHI----GESLVPATMPVLDEIG 59

Query: 63  LTLPVDVIANPQI-----------------FSVKTVDVAASLTRNYQRSYINI------- 98
           +   ++    P+                  F+    D  A+     +R    +       
Sbjct: 60  VMPDIEAAGFPKKYGAAWTSAESRDVPHNGFTGLDHDFKAAEVMFVERDQPGVHRDYTFH 119

Query: 99  -NRHAFDL-WMKSLIPASVEVYHDSLCRK--IWREDDKWHVIFRADGWEQHITARYLVGA 154
            +R  FDL  +K       +V+  +   K     + D   +  R        T R ++ A
Sbjct: 120 VDRGKFDLILLKHAESRGAQVFQKTRVLKADFDTDPDLVTLNCRLGPRTLDFTTRMVIDA 179

Query: 155 DGANSMVRRHLYP--DHQIRKYVAIQQWFAEKHPVPF--------YSCIFDNSITNCYSW 204
            G  +M+   L       +    AI  WF                Y  +    + + + W
Sbjct: 180 SGRQTMLGNQLKVKVPDPVFNQYAIHAWFEGLDRTAMALDPAKRDYIYVHFLPLEDTWMW 239

Query: 205 SISKDGYFIFGGAYPMKDGQTRFTTLKEKM-----SAFQFQFGKTVKSEKCTVLFPSRWQ 259
            I         G    K      +  +EK      S+ +  +    K+E+          
Sbjct: 240 QIPITDTITSVGVVTQKHRFKAASADREKFFWDIVSSRKDIYDALQKAERIRPFKAEGDY 299

Query: 260 DFV---CGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLL---KQPEKLNTAYWR 313
            +       D   LIG+AA F+      G+S AL+S  +    ++   +  +    ++  
Sbjct: 300 SYAMRQICGDRFLLIGDAARFVDPIFSSGVSVALNSARLAAKDVIAAHRAGDFRKESFAT 359

Query: 314 ATRKLRL 320
              KLR 
Sbjct: 360 YEEKLRR 366


>UniRef50_Q9AL91 Alkylhalidase CmlS n=3 Tax=Actinomycetales RepID=Q9AL91_9ACTO
          Length = 577

 Score =  107 bits (268), Expect = 5e-22,   Method: Composition-based stats.
 Identities = 54/302 (17%), Positives = 98/302 (32%), Gaps = 30/302 (9%)

Query: 6   VAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTL 65
           VAIIG GPAGS     L      + + ++            G  L P       R GL  
Sbjct: 6   VAIIGGGPAGSVAGLTLHKLGHDVTIYERSAFPRYRV----GESLLPGTMSILNRLGLQE 61

Query: 66  PVD----VIANPQIFSVKTVDVAASLTRNYQRS-------YININRHAFDLWMK-SLIPA 113
            +D    V      F         + +    +         + + R  FD  +       
Sbjct: 62  KIDAQNYVKKPSATFLWGQDQAPWTFSFAAPKVAPWVFDHAVQVKREEFDKLLLDEARSR 121

Query: 114 SVEVYHDSLCRKIW-REDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIR 172
            + V+ ++    +   + D+  +  R  G    + + +++ A G+   + R L       
Sbjct: 122 GITVHEETPVTDVDLSDPDRVVLTVRRGGESVTVESDFVIDAGGSGGPISRKLGVRQYDE 181

Query: 173 KY--VAIQQWFAEKHPV--PFYSCIFDNSITNCYSWSIS-KDGYFIFG-------GAYPM 220
            Y   A+  +F  K P         +  +  + + W I  KD  +  G        A   
Sbjct: 182 FYRNFAVWSYFKLKDPFEGDLKGTTYSITFEDGWVWMIPIKDDLYSVGLVVDRSKSAEVR 241

Query: 221 KDGQTRF-TTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFIS 279
           + G   F ++   K +      G   + ++  ++    +   V   D  FL G+AA F  
Sbjct: 242 EQGADAFYSSTLAKCAKAMDILGGAEQVDEVRIVQDWSYDTEVFSADRFFLCGDAACFTD 301

Query: 280 AS 281
             
Sbjct: 302 PI 303


>UniRef50_Q0BPD7 Dehydrogenases (Flavoproteins) n=1 Tax=Granulibacter bethesdensis
           CGDNIH1 RepID=Q0BPD7_GRABC
          Length = 449

 Score =  107 bits (267), Expect = 6e-22,   Method: Composition-based stats.
 Identities = 69/387 (17%), Positives = 124/387 (32%), Gaps = 46/387 (11%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
            DV I+G GPAG   A  LA K + + L +K +          G  L P   +   R GL
Sbjct: 21  CDVLIVGAGPAGCTAAYLLAEKGRDVVLLEKERHPRFHI----GESLLPRNLQLIERLGL 76

Query: 64  TLPVDVIANPQIFSVKTVDVA---------ASLTRNYQRSYININRHAFD-LWMKSLIPA 113
           T  +      +  +    D           A            + R  FD    +S    
Sbjct: 77  TEDIATFGVFKPGAEFISDDHGGKDTKFCFADALDKTFTHSWQVKRADFDAALFRSARDK 136

Query: 114 SVEVYHDSLCRKIWREDDKWH-----VIFRAD--GWEQHITARYLVGADGANSMVRRHLY 166
             +V        I   +         ++   D  G   H   RY++ A G ++ +   + 
Sbjct: 137 GADVIDGMRVTTIRFPEGVPEGSARAIVEAVDEAGNAHHFAPRYVIDASGRDTFLGSKVG 196

Query: 167 PDHQI--RKYVAIQQWFAEKHPVP--FYSCIFDNSITNCYSWSIS-KDGYFIFG-----G 216
              +       A+   F    P P      I    +   + W I   D     G      
Sbjct: 197 GKKRNPHNNTAALYAHFRHVTPRPCDRTGYITICLVEGGWFWMIPLPDDITSVGFVGTQE 256

Query: 217 AYPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVC---GKDNAFLIGE 273
           A+  + G      L  +++A      + +++E+ + +  +    + C         +IG+
Sbjct: 257 AFKQRKGSLE-DFLDTRIAASPSVSSRMMQAERISKVTATGNYSYSCERLSGPGWMMIGD 315

Query: 274 AAGFISASSLEGISYALDSTDILRSVL---LKQPEKLNTAYWRATRKLRLKLFG------ 324
           A  F+      G+  A+ S ++   V    L  P        +   K+R  +        
Sbjct: 316 AFAFLDPVFSSGVLLAMTSGEMGAEVADLWLDNPAAARKKLKKVEAKIRHAIGTLSWLVY 375

Query: 325 KIVK--SRCLTAPALRKWIMRSGVAHI 349
           +I K   R +      ++ MR G+  +
Sbjct: 376 RINKPVLRDMFMSPNNRFRMRDGLVSL 402


>UniRef50_D1RDY9 FAD dependent oxidoreductase domain protein n=1 Tax=Legionella
           longbeachae D-4968 RepID=D1RDY9_LEGLO
          Length = 400

 Score =  107 bits (267), Expect = 6e-22,   Method: Composition-based stats.
 Identities = 69/372 (18%), Positives = 116/372 (31%), Gaps = 40/372 (10%)

Query: 5   DVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           DV IIG GPAG+  A  LA     V  ++KK         K CG  ++  +       GL
Sbjct: 4   DVLIIGGGPAGATTAILLAKAGWSVGLIEKKE----FPRKKVCGEFISATSLPLLQILGL 59

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQ-------RSYININRHAFDL-WMKSLIPASV 115
                    P++  V        LT N              + R   D   +       V
Sbjct: 60  EKFYFENGGPEVTRVGLYAGDVILTANMPHMNSSANPYGRALGREYLDTALINEAKLNGV 119

Query: 116 EVYHDSLCRKIWREDDKWHVIFRADGWEQHITARY-LVGADGANSM-VRRHLYPDHQIRK 173
            ++       +  ++  +    + +           +V A G+    +       H+   
Sbjct: 120 TIWQPCEAIHLQNKNGLFFCTIKKEAKISETVCSLRVVMAYGSWGKKIDSSDAKIHKDCD 179

Query: 174 YVAIQQWFAEKHPVPFYSCIFDNSITNCYS-------------WSISKDGYFIF-GGAYP 219
            +A +  F           +   +    Y                I +D        +  
Sbjct: 180 LLAFKAHFKNCSLSKNMMPLL--AFPGGYGGLVHSSPQQVALSCCIRRDTLKNLRLKSPD 237

Query: 220 MKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFIS 279
           +  G+  F  +KE     +  F      +K     P +     C K+  F +G  AG   
Sbjct: 238 LPAGEAVFKYIKEHCRGVREVFELAHIDDKWLAAGPIQPGIRTCYKNGIFFVGNIAGEAH 297

Query: 280 ASSLEGISYALDSTDILRSVLL----KQPEKLNTA---YWRATRKLRL-KLFGKI-VKSR 330
               EGIS A+ S  +L   L+    KQ   LN A   Y +  RK    +++  I +   
Sbjct: 298 PVVAEGISMAMQSAWLLSQSLIQFNMKQNNNLNDAGKYYTQQWRKYFAHRIYASIFLAHL 357

Query: 331 CLTAPALRKWIM 342
            +  P  R  ++
Sbjct: 358 AMLKPWGRALLL 369


>UniRef50_A9A5W1 Dehydrogenase (Flavoprotein)-like protein n=2 Tax=Thaumarchaeota
           RepID=A9A5W1_NITMS
          Length = 378

 Score =  107 bits (267), Expect = 6e-22,   Method: Composition-based stats.
 Identities = 57/329 (17%), Positives = 112/329 (34%), Gaps = 30/329 (9%)

Query: 4   FDVAIIGLGPAGSALARK-LAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +DV + G   AG   AR+  A    V+ +++ ++ GT    + CGGL++    +      
Sbjct: 3   YDVVVAGGSVAGLLCAREIAADGFSVLVIEEDYEIGT---PEHCGGLVSISGLQELGVIP 59

Query: 63  LTLPVD-VIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDS 121
                D +I + +I +        S+    Q+  I I+R   D  +      +       
Sbjct: 60  FRKTFDHMIESAEITAPNGKSF--SINSKNQKV-IEISRRELDKQIAFQAQKNGATI--- 113

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWF 181
             R  ++E     V       E++I  +  V A G +S++ +         +Y     W 
Sbjct: 114 KVRTSFQEMTNTGVRT----NEENIDCKIFVDARGVSSLIHKDRTGILSSAQYEIYADWI 169

Query: 182 AEKHPVPFYSCIFDN-SITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ 240
            +         IFD       ++W I  +     G       G     T+ + ++     
Sbjct: 170 KK----GKVEVIFDQDKYPGFFAWIIPSNEGK--GKIGVAGKGINVSETMDKILAEKGKH 223

Query: 241 FGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVL 300
              T++     +      + FV  + N  ++G+AAG    ++  GI  +          +
Sbjct: 224 --STIRKIFAPIWVKGPIEKFV--EGNTVIVGDAAGQAKPTTAGGIFTSGMGGVYAGQAI 279

Query: 301 LKQPEKLNTA----YWRATRKLRLKLFGK 325
            +  +    +    Y         K F K
Sbjct: 280 SEFLKTDEKSKLEVYQTRWTDRFGKEFEK 308


>UniRef50_D2C3Q7 Electron-transferring-flavoprotein dehydrogenase n=6
           Tax=Thermotogaceae RepID=D2C3Q7_THENR
          Length = 438

 Score =  107 bits (267), Expect = 7e-22,   Method: Composition-based stats.
 Identities = 52/343 (15%), Positives = 113/343 (32%), Gaps = 42/343 (12%)

Query: 3   HFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            FDV ++G GP+G + A  LA   ++V  ++K    G++      GG+L     +  + D
Sbjct: 4   EFDVVVVGAGPSGLSCAYVLAKNGLKVAVVEKGEYPGSKNVM---GGVLYVHPLKEIMPD 60

Query: 62  GLTLPVDVIANPQIFSVKTV----------DVAASLTRNYQRSYININRHAFDLWMKSLI 111
            L    +  A  +    + +              ++      +   + R  FD W    +
Sbjct: 61  FLEKAANSKALERNVIEQNLWLLGNEGVIKIGHRNVEWKENPNAFTVLRANFDRWFAQEV 120

Query: 112 P-ASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQ 170
             A   +   +      R +            +  I ++ +V A+G N ++        +
Sbjct: 121 EKAGALIIPKTKVEDFLRNEKGEIAGVVTSRPKGEIHSKAVVIAEGVNPILTMKAGLRKE 180

Query: 171 IRK----YVAIQQWFAEKHPVPFYSCIFDNSITN-------------CYSWSISKDGYFI 213
             K     VA+++  +    V       + +                   +  +      
Sbjct: 181 DLKPHMVAVAVKEVISVPEDVVNRVFGVEGNDGATIELLGSWSEGMFGMGFLYANRSSVS 240

Query: 214 FGGAYPMKDGQTRFTTLKEKMSAFQ------FQFGKTVKS--EKCTVLFPSR--WQDFVC 263
            G    ++D + +     + +   +         G+   +  E    L P    +     
Sbjct: 241 LGCGVLLEDLRKKKIKPYQLLENLKNHPVISDMLGEYRNNTMEYLAHLIPEGGYYAMPKV 300

Query: 264 GKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQPEK 306
             D   + G+AA  +++   EG ++A+ S  +    LL+  EK
Sbjct: 301 YGDRVLVCGDAAMLVNSIHREGSNHAITSGRLAAETLLEAFEK 343


>UniRef50_Q1IRI6 FAD dependent oxidoreductase n=1 Tax=Candidatus Koribacter
           versatilis Ellin345 RepID=Q1IRI6_ACIBL
          Length = 365

 Score =  107 bits (266), Expect = 7e-22,   Method: Composition-based stats.
 Identities = 56/342 (16%), Positives = 118/342 (34%), Gaps = 18/342 (5%)

Query: 4   FDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +D+ + G GPAG++ A   A    +V+ L++    G     + CG  ++ ++  +  +  
Sbjct: 6   YDLIVAGGGPAGTSAAITAARLGARVLLLEQ----GQFPRHRVCGEFVSAESIETLRQLL 61

Query: 63  LTLP--VDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD 120
             +P  +D+I      S   + +  +       +  +I R+  D  + S    +     D
Sbjct: 62  SHMPHGLDLIERAPKISRTRMFLQGTSVEIPVLASASIPRYDMDAALWSAAKNAGVDCRD 121

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW 180
            +  +    + ++        +             G  S +R  +    + +K + ++  
Sbjct: 122 GVTVESILSNGEFQAATSIGAFIAAAAIA----TTGRWSKLRHPVAKP-KAKKLIGLKAH 176

Query: 181 FAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ 240
           F E +P       F       Y      D   +   A    D  T  +T+ +  S    +
Sbjct: 177 FREANPSLSTDLYF---FPGGYCGVQPIDANTVNAAALVRADLATDLSTVFQLNSQLAKR 233

Query: 241 FGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVL 300
                         P  + +    +D+    G+AAGFI   + +GIS AL +        
Sbjct: 234 TRVWEPVTDLVTTAPLIYAEPEPERDDLLFAGDAAGFIDPFAGDGISLALRTGAAAAQAA 293

Query: 301 LKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIM 342
           +        +   A R  R +   + +      A A  +W++
Sbjct: 294 M-HSITGRVSAAEAARTYRRRYEQQFL--PAFRAAAQARWLL 332


>UniRef50_B8GGY5 Geranylgeranyl reductase n=1 Tax=Methanosphaerula palustris E1-9c
           RepID=B8GGY5_METPE
          Length = 388

 Score =  107 bits (266), Expect = 8e-22,   Method: Composition-based stats.
 Identities = 73/336 (21%), Positives = 118/336 (35%), Gaps = 37/336 (11%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           M+ +DV ++G GPAG+A A   A       + ++H  GT G+   C GLL+  A      
Sbjct: 4   MKPYDVVVVGAGPAGTAAAASCAAAGLSTLVIEEH--GTIGYPVQCAGLLSEAAFAE--- 58

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNY-----QRSYININRHAFDLWMKSLIPASV 115
                   V   P + +V+   +A+ L  +      +     ++R   D  M      + 
Sbjct: 59  ------CRVSERPVLNTVRGARIASDLGGSLLFDAGKTKAFVVDRGLLDREMAVAAADAG 112

Query: 116 -EVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKY 174
            E    +    I        V+      EQ I  R L+GADG  SMV R L         
Sbjct: 113 AEFMLKTGFTSI----SGDRVMTCGIHGEQSIGYRLLIGADGPRSMVTRSLGLPRAQTYL 168

Query: 175 VAIQQWFAEKHPV-PFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEK 233
             IQ   A   PV P +  I+ ++    + W I      I  G       + +F   + +
Sbjct: 169 SGIQADLAVADPVDPRFVEIYPDASPEFFGWQIPLAPRRIRVGLCGTCGVREKFERFQAR 228

Query: 234 MSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDST 293
                            T   P        GK  A ++G+AAGF   +S  G+   + S 
Sbjct: 229 FPGSCLHL--------VTGTIPLGVIGKTYGKQ-ALIVGDAAGFAKPTSGGGVYTGIRSA 279

Query: 294 DILRSVLL------KQPEKLNTAYWRATRKLRLKLF 323
            +     +      +  +   + Y +A +    K  
Sbjct: 280 RLAAETAIACIEEGRFDDAALSRYEKAWQDDFGKEL 315


>UniRef50_B2A3V3 FAD dependent oxidoreductase n=2 Tax=Clostridia RepID=B2A3V3_NATTJ
          Length = 436

 Score =  107 bits (266), Expect = 8e-22,   Method: Composition-based stats.
 Identities = 62/369 (16%), Positives = 122/369 (33%), Gaps = 45/369 (12%)

Query: 2   EHFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPD-AQRSFI 59
           E++D  ++G GP GS+ A  +A   + V   +K ++ G +      GG +     Q +F 
Sbjct: 3   EYYDAIVVGAGPGGSSAAYHMAQQGLNVALFEKGNKPGDKNVY---GGTIYRRSTQEAFP 59

Query: 60  RDGLTLPVD--VIANPQIF----SVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIP 112
                 P++  VI +   F    S   +       +    +     R  FD W+ +    
Sbjct: 60  GFWEEAPLERTVITDEVWFLEHDSAVKMGFTGLEFKKPPYNKFTALRSKFDNWLAEQAKD 119

Query: 113 ASVEVYHDSLCRKIWREDDKWHVIFRADGWEQ----HITARYLVGADGANSMVRRHLYPD 168
              E+Y ++L   +  +        R  G +      I A  ++ A+G N+ +       
Sbjct: 120 VGAELYTNTLVTDLLYQKGFLASGKRIKGVKLYDGTQIKAGVVILAEGVNAPLAHQAGLR 179

Query: 169 HQIRKYV--------------AIQQWF----AEKHPVPFYSCIFDNSITNCYSWSISKDG 210
            ++                   I++ F     E   + F       S      W+   + 
Sbjct: 180 KKLPTNAFTLYTCETLALSPKTIEERFELESGEGATIGFAGFPTSGSSGKGGLWTNHDNL 239

Query: 211 YFIFGGAY-PMKDGQTRFTTLKEKMSAF-----QFQFGKTVKSEKCTVLFPSRWQDFVCG 264
             I GG    M   Q     + E+  +            +++ +   +            
Sbjct: 240 SIIVGGRLNEMVSKQLNPHHMLERFKSHPLIKRLLHGADSLEYKAYMIPKGGYSLMPKLF 299

Query: 265 KDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQ---PEKLNTAYWRATRKLRLK 321
            D   ++G+AA  IS     G   A+ S       +++     +    +    + KL  +
Sbjct: 300 SDGVLIVGDAAIMISGR--RGTDLAMISGKKAAETVVQAKAREDFSKKSLANYSHKLNQQ 357

Query: 322 LFGKIVKSR 330
            F K +KS+
Sbjct: 358 FFMKDIKSK 366


>UniRef50_Q8KLM2 StaK n=1 Tax=Streptomyces toyocaensis RepID=Q8KLM2_STRTO
          Length = 435

 Score =  107 bits (266), Expect = 9e-22,   Method: Composition-based stats.
 Identities = 61/335 (18%), Positives = 103/335 (30%), Gaps = 40/335 (11%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR- 60
           E FDV + G GPAGS  A  +A +   + L +K            G  L P       R 
Sbjct: 4   ETFDVVVAGGGPAGSTAASLVAMQGHRVLLVEKEVLPRHRV----GESLLPSTVHGVCRM 59

Query: 61  DGLTLPVDVIANPQIFS------------VKTVDVAASLTRNYQRSYININRHAFDL-WM 107
            G+T  +     P                  +   ++ LT     +Y   +R  FD   +
Sbjct: 60  LGVTDELAETDFPVKRGATFQWGGRAEPWAFSFGASSRLTDATSFAY-QADRARFDEILL 118

Query: 108 KSLIPASVEVYHDSLCRKIWREDDKWHVIFRA--DGWEQHITARYLVGADGANSMVRRHL 165
           K+     V V        +  E D+   +     DG E  + AR+++ A G  S +   +
Sbjct: 119 KNAKRKGVVVREGCSVTAVVEEGDRVTGLRHTDPDGGEHEVGARFVIDASGHESPLSASV 178

Query: 166 YPDHQIRKYV---AIQQWFAE---KHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYP 219
                        A+  +F     + P P        +    + W +   G     GA  
Sbjct: 179 GGTRDRAGSFRGLALSGYFGNGCKRLPEPRSGDGLSVTFDGGWFWYVPLFGGLTSVGAVV 238

Query: 220 --------MKDGQTRFTTLKEKMSAFQFQFGKTVKS-----EKCTVLFPSRWQDFVCGKD 266
                     D +  F  L  +  A      + ++       K  V     +      + 
Sbjct: 239 SEERAEKLQDDREEAFKALIAECPAISDLLSEGMRVTAGKYGKLRVREDYVYHRTTFWRP 298

Query: 267 NAFLIGEAAGFISASSLEGISYALDSTDILRSVLL 301
              L+G+AA  +      G+  A  S  +    + 
Sbjct: 299 GMLLVGDAACSVDPLFSSGVHLATYSALLAARSIN 333


>UniRef50_P54805 Uncharacterized protein in nifH2 5'region n=5
           Tax=Methanosarcinaceae RepID=YNH2_METBA
          Length = 186

 Score =  106 bits (265), Expect = 1e-21,   Method: Composition-based stats.
 Identities = 41/169 (24%), Positives = 69/169 (40%), Gaps = 14/169 (8%)

Query: 3   HFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            +DV ++G GPAGS  A   A     V+ LDKK + G+      C G L   ++   +  
Sbjct: 6   SYDVVVVGAGPAGSTAAMYAAKNGASVLLLDKKREIGS---PIQCAGFLPDASEVQALLR 62

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRN-----YQRSYININRHAFDLWM-KSLIPASV 115
              LP  +   P    ++ +D     T N     +      ++R  +D ++ +    A  
Sbjct: 63  EAMLPDTLKNYPDSCVLQRIDNQRIFTPNCNIKEFAVRGAVLDRCRYDQFLAEQAARAGA 122

Query: 116 EVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRH 164
           E+   +   KI        V       +  I A+ ++GADG NS+V + 
Sbjct: 123 ELMIKTRVTKIE----GTTVETSGVFGKYRIKAKAIIGADGPNSLVAKS 167


>UniRef50_D2RYX8 FAD dependent oxidoreductase n=5 Tax=Halobacteriaceae
           RepID=D2RYX8_9EURY
          Length = 413

 Score =  106 bits (264), Expect = 1e-21,   Method: Composition-based stats.
 Identities = 56/321 (17%), Positives = 103/321 (32%), Gaps = 32/321 (9%)

Query: 2   EHFDVAIIGLGPAGSALARKL-AGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
             +DV I G GPAG   AR L A    V+ L+ + +      S        P    SF  
Sbjct: 3   NRYDVVIAGAGPAGGQCARDLVARGYDVVVLETESEDEFPRQSNKSTAGTFPSMMASF-- 60

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVYH 119
               +P DV+   Q      ++         Q   + +    F  ++ +       E   
Sbjct: 61  ---GIPDDVV--MQYTDSVVLESPTDHYVQEQPGAV-LEFADFKRFLVEDGRDGGAEYLF 114

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQ 179
           D+       E+ +  V  R +G E+ +    ++ A G ++ + + L      R+  AI  
Sbjct: 115 DARVTAPIMENGEI-VGVRYNGDEE-VYGDIVIDATGPSAPLAKKLDVVDLKRENHAIGI 172

Query: 180 WFAEK----------HPVPFYSCIFDNSI-TNCYSWSIS-KDGYFIFGGAYPMKDGQTRF 227
            +  +                    D+ I    YSW     +     G  Y   +  +R+
Sbjct: 173 EYEFEGIDIDRPGFADLNDAMMLRLDHEIAPGGYSWVFHTGEDTAKVGLCYLQNEHHSRY 232

Query: 228 ----TTLKEKMSAF---QFQFGKTVKSEKCTVLFPSRWQ-DFVCGKDNAFLIGEAAGFIS 279
                T+ + +  +     +F    + E       +  Q       D    IG+    + 
Sbjct: 233 AKDGHTVDDYLEHWLETDPRFANAERLEGKQHRGSAHLQLPERMHTDRFMAIGDTVPTVD 292

Query: 280 ASSLEGISYALDSTDILRSVL 300
               EGI+  + S  +    +
Sbjct: 293 PLWGEGINKCMQSGRVAAVAV 313


>UniRef50_A8MAE2 Geranylgeranyl reductase n=6 Tax=Thermoproteaceae
           RepID=A8MAE2_CALMQ
          Length = 459

 Score =  105 bits (262), Expect = 2e-21,   Method: Composition-based stats.
 Identities = 58/334 (17%), Positives = 114/334 (34%), Gaps = 23/334 (6%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
           + +DV I+G G AGS  A  +A +   +AL ++     E   K  G  +         + 
Sbjct: 3   KTYDVLIVGAGTAGSYAAYLMAKQGLSVALVERK--RAEEVFKVTGDAIGKHHIEELTKS 60

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDS 121
           GL++  DV       +        S+          ++   +  W+ +    S     D+
Sbjct: 61  GLSISNDVFMIKYEGAELYSP-DLSIKYFVAGEGYGLDIGKWAQWLINAANNSGADIIDN 119

Query: 122 LCRKIWREDDKWHVIF---RADGWEQHITARYLVGADGANSMVR-------RHLYPDHQI 171
                   +  +       R DG +  + A+  V A GA  +VR       R   P    
Sbjct: 120 HTVSTPIIEGGFVKGVKASRRDGTQVELRAKVTVDASGATGVVRTKLPSQYRISEPLLPE 179

Query: 172 RKYVAIQQW----FAEKHPVPFYSCIFDNSITNCYSWSISKDGYF-IFG----GAYPMKD 222
               A ++     ++  +P      + +N     Y W   K       G    G    ++
Sbjct: 180 DASYAYREIVEVDYSIPNPQNIRIYLDNNISPGGYWWFFPKSDRVANVGLGIWGRLVKEN 239

Query: 223 GQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASS 282
           G       ++ +++  +  G+ +       + P+R             +G+AA  ++   
Sbjct: 240 GLNPRINYEKYLASSPYVKGRKL-LHTGGGIVPTRRPLASMVGPGIVAVGDAAVAVNPIH 298

Query: 283 LEGISYALDSTDILRSVLLKQPEKLNTAYWRATR 316
             GI  AL S+ +    +++  EK + +     R
Sbjct: 299 GGGIGPALLSSALASKAIIEALEKGDVSEAGLWR 332


>UniRef50_Q0Q5F4 Halogenase n=8 Tax=Actinomycetales RepID=Q0Q5F4_9ACTO
          Length = 458

 Score =  105 bits (262), Expect = 2e-21,   Method: Composition-based stats.
 Identities = 55/320 (17%), Positives = 99/320 (30%), Gaps = 30/320 (9%)

Query: 6   VAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           V +IG GPAGS  A  LA +  QV  L+++            G  + P  +  F   G+ 
Sbjct: 7   VLVIGGGPAGSTAAGLLARQGVQVTLLERETFPRYHI-----GESILPSCRPIFELLGVW 61

Query: 65  LPVDVIANPQIFSVKTVDVAASLTRNYQR------SYININRHAFDLWMKSLIPA-SVEV 117
             V+                      +        +   + R  FD  +        V+V
Sbjct: 62  DKVEAFGFQPKGGAYFSWGPDEWEVRFAELGADGANAWQVTRADFDKLLLDHSRELGVDV 121

Query: 118 YHDSLCRKIWREDDK-WHVIFRADGWEQHITARYLVGADGANSMVR-RHLYPD--HQIRK 173
           +     ++I  + D+     +  DG    +T  YL+ A G   ++  ++L     H + +
Sbjct: 122 HEGVTVKEIEFDGDRPVAARWAGDGKTGRLTFDYLIDASGRRGVMATKYLGARTFHSVFR 181

Query: 174 YVAIQQWFAEKHPVPFYSC--IFDNSITNCYSWSIS-KDGYFIFGGAYPMKDGQTR---- 226
            VA   ++    P+       I   S+   + W+I   DG    G          R    
Sbjct: 182 NVATWSYWKNAKPLDRGPAGSITVASVPEGWFWAIPLHDGTTSVGLVTGRDTFNRRRREQ 241

Query: 227 ------FTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISA 280
                 +     +    Q       +           +           L G+AA F+  
Sbjct: 242 GGIEAVYDDALRQCPLVQELLADAERVSDFKTEQDYSYTSETFHGPGYLLCGDAACFLDP 301

Query: 281 SSLEGISYALDSTDILRSVL 300
               G+  A  S  +  + +
Sbjct: 302 LLSTGVHLATYSAMLAAASI 321


>UniRef50_A6C2B8 Putative uncharacterized protein n=1 Tax=Planctomyces maris DSM
           8797 RepID=A6C2B8_9PLAN
          Length = 387

 Score =  105 bits (261), Expect = 3e-21,   Method: Composition-based stats.
 Identities = 59/370 (15%), Positives = 133/370 (35%), Gaps = 28/370 (7%)

Query: 2   EHFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           + +DV +IG GPAG+  AR+LA  K++ + +++K    T    K CG  L   A  +  +
Sbjct: 15  QSWDVIVIGAGPAGAVAARQLALQKLRTLLIERK----TFPRYKVCGCCLNQRAINALQQ 70

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVYH 119
            GL   ++      +   +          +     + I+R  FD  + +S I A      
Sbjct: 71  IGLGQLLESAGAVPLTQFRMQYQGRKAAVSLP-GGLAISREVFDTLLVQSAIDAGAAYLQ 129

Query: 120 DSLCRKIWREDDKWHVIFR---ADGWEQHITARYLVGADGANSM-VRRHLYPDHQIRK-- 173
           ++    +   + +                ++A+ ++ ADG     ++     D Q+    
Sbjct: 130 ETSATIVDSAEKRSSRTVELNFQGHTAGSVSAKIVLAADGLGHPSLQNCAGFDMQVASDS 189

Query: 174 YVAIQQWFAEKHPVPFYSCIFDNSI--TNCYSWSISKDGYFIFGGAYP---MKDGQTRFT 228
            + +   F  K+   + + +   +I  +        +        A     MK       
Sbjct: 190 RIGVGAAFVVKNQSSYPAGLIHMAIHKSGYVGLVRVEGDLLNLAAAIDRDFMKQCAGPAD 249

Query: 229 TLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISY 288
            + + + A +      +         P   +      +  F++G+AAG++   + EG++ 
Sbjct: 250 AVLQILRASESPLLPEMTESNFKGTLPVTRKTLRPVGNRLFILGDAAGYLEPFTGEGMAN 309

Query: 289 ALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKL----------FGKIVKSRCLTAPALR 338
           A+     +  ++ +     ++A  +   K    L            ++++S       LR
Sbjct: 310 AITEGMAVAQLVPQGLRHWDSALEQKWLKAHYALTEGRLFWCRWLARLLRSPAAVGWGLR 369

Query: 339 KWIMRSGVAH 348
            + +  G+A 
Sbjct: 370 LFHLFPGMAR 379


>UniRef50_D2BAB1 Dehydrogenase (Flavoprotein)-like protein n=1 Tax=Streptosporangium
           roseum DSM 43021 RepID=D2BAB1_STRRD
          Length = 671

 Score =  105 bits (261), Expect = 3e-21,   Method: Composition-based stats.
 Identities = 65/343 (18%), Positives = 112/343 (32%), Gaps = 20/343 (5%)

Query: 6   VAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTL 65
           V I+G GPAG+  A +LA       L  +     +        +L+  A R     G   
Sbjct: 9   VLIVGAGPAGAITAAELARHGLRAVLAGEEAGEADHDV-----VLSGAAMRGLASLGALE 63

Query: 66  PVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLCRK 125
            V       +      D    L      +    +R      ++ +  A+   +       
Sbjct: 64  EVGARVVGTVELRLGQDGGHVLPEAVNSA---CDRRHLVEGLRRIAVAAGATWLPGRVTD 120

Query: 126 IWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEKH 185
           + R +  WH    A   +  ++AR+LV A GA+S    H       R Y  +    +   
Sbjct: 121 LERREGTWH----ASIGDTAVSARHLVVATGASSAGTPHATGLLCARPYSGVNLTESIVL 176

Query: 186 PVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPM---KDGQTRFTTLKEKMSAFQFQF- 241
            +P    I       C  W++                  D      T +  ++    +F 
Sbjct: 177 ALPAPRTIDPAERPTCV-WAVPGAQAGTCTIGASRLGAGDPDDLLETARAVLAEGDQRFA 235

Query: 242 GKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLL 301
           G T      T +  S +       D   L+G+AAG ++  + EG+SYA+ S  +    + 
Sbjct: 236 GATPAGPPVTGVLNSGFAPEHSVHDGRLLVGDAAGLVNPFTGEGLSYAVQSAVLAARAIA 295

Query: 302 KQPEKLN---TAYWRATRKLRLKLFGKIVKSRCLTAPALRKWI 341
             P+  +    AY R      +  F     +      A R  +
Sbjct: 296 DHPDDPDAAGRAYTRRLSATFVGYFETATHAARRYHLAWRVLV 338


>UniRef50_C5V9R0 FAD-linked oxidoreductase n=2 Tax=Corynebacterium matruchotii
           RepID=C5V9R0_9CORY
          Length = 463

 Score =  105 bits (261), Expect = 3e-21,   Method: Composition-based stats.
 Identities = 51/344 (14%), Positives = 93/344 (27%), Gaps = 53/344 (15%)

Query: 24  GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTVDV 83
             +  + +D +         K CG  L P A        L L   V+A  +   +K    
Sbjct: 39  RGISTLLIDAQ----PFPRDKTCGDGLTPRA--IHQLQLLGLADSVVARYRSHGLKLHGF 92

Query: 84  AASLTRNYQRSYIN-----INRHAFDLWMKSLIPAS------------------------ 114
             S+T  +  S        + R  FD ++     +                         
Sbjct: 93  GGSVTAPWPESAFGTVGSAMPRREFDDFLVGCARSHPSVEFLGGVRAVAVSMSTPVGAGS 152

Query: 115 VEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKY 174
             +   S             V          +  + ++ ADG  S + + L       + 
Sbjct: 153 DSIISGSGIMSGDAASVGALVAAVELSDGSWVRPKQVIVADGVRSPIGKLLGRTWHKGEV 212

Query: 175 VAIQQWFAEKHPVPFYSCIF--------DNSITNCYSWSIS-KDGYFIFGGAYPMKDGQT 225
             I        P      I         D      Y W     +G    G      D + 
Sbjct: 213 YGIAARSYCATPRSEEPWIHSHLELRDADGVAQPGYGWIFPLGNGLANVGCGALSTDRRP 272

Query: 226 RFTTLKEKMSAF----QFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISAS 281
                K+ +  +    + ++G        + L P           N  LIG+AA  ++  
Sbjct: 273 ARINTKKLLGLYAQQCRPEWGFGAPDRVASALLPMGGAVSGVAGRNWMLIGDAAACVNPL 332

Query: 282 SLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGK 325
           + EGI Y +++  +    L          Y      +  + +G+
Sbjct: 333 NGEGIDYGMETARLAVECL-----GAGKDYTLLWPDVLRREYGE 371


>UniRef50_A8FB69 Possible monooxygenase n=3 Tax=Bacillus RepID=A8FB69_BACP2
          Length = 377

 Score =  104 bits (260), Expect = 4e-21,   Method: Composition-based stats.
 Identities = 62/358 (17%), Positives = 127/358 (35%), Gaps = 36/358 (10%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M+  +V IIG G AG A A  L    M+    + +     E  +   G LL+P+  +   
Sbjct: 1   MKSQNVIIIGSGVAGLATALFLKKAGMESTIYESRSDEELETGA---GFLLSPNGVKILD 57

Query: 60  RDGL--TLPVDVIANPQIFSVKTVDVAASLTRNYQRSY-----ININRHAF-DLWMKSLI 111
             G    +  +     +I  + + +   ++  NY   Y     +N+ R       +K + 
Sbjct: 58  GIGCKNEVIANATVIKKIQQINSENEVEAIFYNYSEKYYDAPLLNVMRDQIIQSLLKEVH 117

Query: 112 PASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQI 171
              +EV ++     I ++     V+F     E  IT   ++GADG  S  R  +  + ++
Sbjct: 118 RQGIEVKYNKKLTSIKQQPHSVQVLFE---DETVITGDIVIGADGTFSKTREAIAFNAKL 174

Query: 172 --RKYVAIQQWFAEKHPVPFYSCIFDNSITNC---YSWSISKDGYFIFGGAYPMK----- 221
               +  +Q     K  V   +  +  +  N    +  +   +   I   A+        
Sbjct: 175 DYSGFWGLQGVSFVKDFVLDEATSYFYNDGNFQFIFGKAHPTNKMNILWQAFSQCPEKLP 234

Query: 222 -------DGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVC----GKDNAFL 270
                  + +T    L ++M  +          +   + FP    +        K    L
Sbjct: 235 TKHFEKANKETILQLLYKQMEGWNIPKHLFAIIDHTEMFFPRSIYEIKNLSVWSKGRVVL 294

Query: 271 IGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVK 328
           +G+A    +    +G SY+L+   ++  +L     +    Y+   R+ R +    + +
Sbjct: 295 VGDAVHTANPFVGQGASYSLEDAMLIAKMLRDHDYRDAFYYYEKDRRKRTEELNALFQ 352


>UniRef50_Q7USU8 Probable alkylhalidase homolog n=1 Tax=Rhodopirellula baltica
           RepID=Q7USU8_RHOBA
          Length = 374

 Score =  104 bits (260), Expect = 4e-21,   Method: Composition-based stats.
 Identities = 64/334 (19%), Positives = 114/334 (34%), Gaps = 25/334 (7%)

Query: 1   MEHF-DVAIIGLGPAGSALARKL-AGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSF 58
           M  + DV +IG GPAG + A +L      V  ++K             G  LAP+A    
Sbjct: 1   MSQYSDVMVIGGGPAGCSTALRLRQQGATVTLIEKSDYSQQRP-----GESLAPEAIGFL 55

Query: 59  IRDGLTLPVDVIA----NPQIFSVKTVDVAASLTRNYQRS-YININRHAFDLWMKSLI-P 112
            + G+    D  A    +  + S  +V ++ S           N++R  FD  +      
Sbjct: 56  NQLGVRDRFDAEAFQQTSGLLVSWGSVGISFSSFLTRPFGSGWNLDRARFDRMLSHACRQ 115

Query: 113 ASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVR-RHLYPDHQI 171
           +SV+V       +     D+W +    D       +  +V A G  S +  R        
Sbjct: 116 SSVKVVFSRQSIQFVYSHDRWELQVGRD----SYRSPVIVDATGRASAMATRFGVQRIHD 171

Query: 172 RKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKD----GYFIFGGAYPMKDGQ--T 225
              +A+  +  E+   P    I        YS  +  D     +       P +  +  T
Sbjct: 172 DHLIALVSYRDEQSCDPRLV-IESTPDGWWYSAGLPGDVSVTAFLTDVDLIPKRPEERTT 230

Query: 226 RFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEG 285
            FT L E+          +  +    ++  +  +       + F +G+AA   S  S  G
Sbjct: 231 YFTELLEQTRFAHRGIAPSSPAFSPRLVRANTSRLSRPSSSHWFAVGDAAIATSPLSGNG 290

Query: 286 ISYALDSTDILRSVLLKQPEKLNTAYWRATRKLR 319
           I  AL++  +    ++      +  Y      +R
Sbjct: 291 IVRALETGLLAADAIVSTDTNASQRYNEVLASMR 324


>UniRef50_Q1QK25 Monooxygenase, FAD-binding n=2 Tax=Nitrobacter RepID=Q1QK25_NITHX
          Length = 401

 Score =  104 bits (260), Expect = 4e-21,   Method: Composition-based stats.
 Identities = 67/332 (20%), Positives = 111/332 (33%), Gaps = 44/332 (13%)

Query: 3   HFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            +DV I+G GPAG+A A  LA    +V+ ++K+         K  G  L P +       
Sbjct: 13  TWDVVIVGSGPAGAATAITLARYGQRVLLVEKRGS----PRFKL-GESLPPTSIGLVKHF 67

Query: 62  GLTLPVDVIANPQIFSV-KTVDVAASLTRNYQRSY-------ININRHAFDLWMK-SLIP 112
                      P +F+    V + A+   +    +       + ++R AFD  ++ + + 
Sbjct: 68  LADPDGPEQQLPGLFNTAGNVSLWATGQADITDFFFTSTGHGLCVDRLAFDEALRTTAVA 127

Query: 113 ASVEVYHDSLCRKIWREDDK---WHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDH 169
           A   +      +   R  D    W +   +    +   ARYLV   G  ++V R L    
Sbjct: 128 AGATLLRGVGFQSCARIADGSFNWQLTLSSGAGTRQHRARYLVDCSGRPAVVARSLGVPT 187

Query: 170 QIR--KYVAIQQWFAEKHPVPF-YSCIFDNSITNCYS----------------WSISKDG 210
                +  A  QWF+        Y+ I        YS                W   KD 
Sbjct: 188 VPNDDRLFAYAQWFSCTSADDDRYTRIEAAPHGWWYSNRLPSTEGSETRRLVVWHTDKDL 247

Query: 211 YFIFGGAYPMK--DGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNA 268
                 AY           T +   + A  +    T++          R +DF    D  
Sbjct: 248 PAAKMAAYRQGFEQLLDDSTHIAPLLRARGYHPCGTIRGAPANSQ---RLRDF--CGDAW 302

Query: 269 FLIGEAAGFISASSLEGISYALDSTDILRSVL 300
             +G+AA      S +GI  AL +      ++
Sbjct: 303 MAVGDAAQAYDPLSSQGIDKALRTASHAGHMI 334


>UniRef50_D2S022 FAD dependent oxidoreductase n=1 Tax=Haloterrigena turkmenica DSM
           5511 RepID=D2S022_9EURY
          Length = 438

 Score =  104 bits (260), Expect = 4e-21,   Method: Composition-based stats.
 Identities = 61/333 (18%), Positives = 121/333 (36%), Gaps = 50/333 (15%)

Query: 4   FDVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           FDV ++G G AG+A A KLA +   V  +++  Q G +  +   GG+L  +     +   
Sbjct: 7   FDVVVVGSGRAGTAAAYKLAKEGVDVALVERAKQPGMKNVT---GGVLYGEIMDDLVP-E 62

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNY------QRSYININRHAFDLWMKSLIPASVE 116
                 +  +    ++K +   A +  +Y      +     +    FD W          
Sbjct: 63  YPEEAPLERHVVEHNIKLLHGDAEVGISYRDQELREEPNYTLMLGKFDRWFVEKAEERGA 122

Query: 117 VYH-DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDH------ 169
           V+  ++    + + DD   V    +G +  I  + ++GADG N+ V R            
Sbjct: 123 VFVPETTVIDVTQTDDGAVVHTDREGGD--IACQAVIGADGVNTTVGRKTGIQRTMHNRD 180

Query: 170 ---QIRKYVAI-QQWFAEKHPVPF-------YSCIFDNSITNCYSWSISKDGYFIFGGAY 218
               ++K + + ++   E+  +         Y+   + + T  Y +  + +     G   
Sbjct: 181 MALSVKKVIQLDRETINERFSLDGDEGAAYVYTGFPEGAPTIGY-FIYTFEDRISVGAVG 239

Query: 219 PM------------KDGQTRFTTLKEKMS--AFQFQFGKTVKSEKCTVLFPSRWQDFVC- 263
            +            K G   ++ L++ M   A +      V  E   +L P    D +  
Sbjct: 240 SLEVLRHLGDEGYGKTGTPLYSLLEQFMELDAVRPYVAGDVLDEYQGILVPEFSYDTLPD 299

Query: 264 -GKDNAFLIGEAAGFI--SASSLEGISYALDST 293
                  L+G+AAG +     +  G+ Y + S 
Sbjct: 300 RYDRRVALVGDAAGLVLNKGYTFRGLDYGITSG 332


>UniRef50_B0C5X8 Tryptophan halogenase, putative n=1 Tax=Acaryochloris marina
           MBIC11017 RepID=B0C5X8_ACAM1
          Length = 473

 Score =  104 bits (259), Expect = 5e-21,   Method: Composition-based stats.
 Identities = 61/344 (17%), Positives = 122/344 (35%), Gaps = 36/344 (10%)

Query: 3   HFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            FDV +IG GPAGS ++ +LA    +V  ++ +                +       + D
Sbjct: 8   TFDVCVIGGGPAGSVVSHRLASLGYKVCIIESQKFPRPNHI------GASLLPSTLPLLD 61

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQ----RSYININRHAFDLWMKSLIPASVEV 117
            + +   V     +   +T+   +     Y+    +   +++R  FD  +      +   
Sbjct: 62  CIGVRESVENTGFLLHERTIVWWSETFPIYKNQHEQPGFHVDRGQFDQLLLQNAKENGVE 121

Query: 118 YHD--SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMV--RRHLYPDHQIRK 173
            H      R    +  KW +  R DG ++ I ++ +V A G  S+V  RR L        
Sbjct: 122 VHQPAHAFRPERIKTQKWQIRIRQDGMQRTILSKIVVDASGGRSLVPGRRILASA----P 177

Query: 174 YVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDG---------Q 224
            +A+  ++   +     + I          W             +              +
Sbjct: 178 LLALYAYWKGTNFQTIEARIEAGESEWF--WYAPLSQNKAVTAVFLDPSCLSLNSKQGIE 235

Query: 225 TRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLE 284
             +  L  +   F  +F K ++ +       +R+ +   G D+   IG+A   +   S +
Sbjct: 236 NIYHKLLNRFRLFPAKFIKGIEGKVKICDASTRYAENPIG-DSFIRIGDACLCLDPLSSQ 294

Query: 285 GISYALDSTDILRSVL---LKQPEK--LNTAYWRATRKLRLKLF 323
           GI  A+ S      ++   LK PE   L  +++ A +K +   +
Sbjct: 295 GIQSAVASGLQAAIIINTFLKYPEDTELAISFYNARQKEKRNEY 338


>UniRef50_UPI000038E09B FixC protein n=1 Tax=Ferroplasma acidarmanus fer1
           RepID=UPI000038E09B
          Length = 397

 Score =  104 bits (259), Expect = 6e-21,   Method: Composition-based stats.
 Identities = 60/333 (18%), Positives = 117/333 (35%), Gaps = 30/333 (9%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           M  +D+ I+G GPAGSA A K A + + + + ++   G E  SK   G            
Sbjct: 1   MLEYDIVIVGAGPAGSAAALKAASEGKKVLVIER---GPEPGSKNVSGAEVRK-DYITSV 56

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLI-PASVEVYH 119
            G  +P +   +    S+   D   ++   +    +   R   D W+ S+   A   +  
Sbjct: 57  FGEGMPYERTVDTMKLSLYEKDKPVNI-DFHPEGLVTTGRLKLDKWLSSVSEQAGATIIP 115

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLY------PDHQIR- 172
            +   K+  E+     +    G    + A+  V A+G N++V  +        P + ++ 
Sbjct: 116 KTTALKLNWENGIAKSLTTDRGD---VAAKSFVLAEGVNALVSMNSGINVDWTPSNSVQA 172

Query: 173 -------KYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQT 225
                  K   +   F         S     S      +  +       G   P+K+   
Sbjct: 173 VKMVYSIKKGDLNNIFGFPDDDTGMSWRMIMSDPLVAGFMYTYKDSLAVGIGSPIKELVD 232

Query: 226 RFTTLKEKMSAF-------QFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFI 278
           R    +  +  F       +   G +++     V+    + +    K N +L G+A G +
Sbjct: 233 RKIRPEALLDKFLETTGIAEKVKGYSLREYSAKVIPEGGFPETNVAKGNVYLCGDAIGLV 292

Query: 279 SASSLEGISYALDSTDILRSVLLKQPEKLNTAY 311
              + +GI+ A+ S  +     +   +K    Y
Sbjct: 293 DPLTFDGITPAIASGTLAGEAAVMNYDKEVYRY 325


>UniRef50_D0ZCG4 Oxidoreductase n=5 Tax=Enterobacteriaceae RepID=D0ZCG4_EDWTE
          Length = 448

 Score =  104 bits (258), Expect = 6e-21,   Method: Composition-based stats.
 Identities = 71/379 (18%), Positives = 120/379 (31%), Gaps = 52/379 (13%)

Query: 4   FDVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           FD  I+G G AG   A  LA     V+ +++ +  G +  +   GG L        I   
Sbjct: 24  FDAIIVGAGLAGCVAALVLARAGANVLVIERGNYAGAKNVT---GGRLYAHTLERIIPGF 80

Query: 63  -LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSY------ININRHAFDLWMKSLIPASV 115
               PV+     +  S  T D A +L  +  R         ++ R  FD W+     A+ 
Sbjct: 81  AEQAPVERRITHEKISFLTADSAVTLDYHNARDGAAEAASYSVLRGKFDTWLMEQAEAAG 140

Query: 116 EVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLY--PDHQIRK 173
             +   +      + D   V   ADG E  + A  ++ A+G N+++   +         K
Sbjct: 141 AQFIPGIRVDRLIQRDGRVVGVEADGDE--LEANVVILAEGVNALLAEQIGMVQPRVEAK 198

Query: 174 YVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSI---SKDGYFIFGGAYPMKDGQ------ 224
            VA+      + P       F     +  +W       DG  + GG +   +G       
Sbjct: 199 NVAVGVKELIELPRELLEARFALQGNDGTAWLFAGTPSDG--LMGGGFLYTNGDSLSLGI 256

Query: 225 ---------------TRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQ-DFVCGKDNA 268
                                K+  +      G         V+  +          D  
Sbjct: 257 VCGLHHIEQAGKSIPQMLEDFKQHPTVRPLIEGGKTVEYAAHVVPEAGINMQPKLVADGV 316

Query: 269 FLIGEAAGFI--SASSLEGISYALDSTDILRSVLLKQPEKLN------TAYWRATRKL-R 319
            L G+AAG       ++ G+  A+ S +     +L   EK +        Y R    L  
Sbjct: 317 LLAGDAAGMCLNLGFTIRGMDLAIASGEAAARAVLAAREKNDFSAAGLAEYPRLLESLPV 376

Query: 320 LKLFGKIVKSR-CLTAPAL 337
           +K      K    +  P +
Sbjct: 377 MKELRHYRKVPQMMDNPRM 395


>UniRef50_Q1Q5X9 Hypothetical FAD oxidoreductase protein n=1 Tax=Candidatus Kuenenia
           stuttgartiensis RepID=Q1Q5X9_9BACT
          Length = 898

 Score =  104 bits (258), Expect = 7e-21,   Method: Composition-based stats.
 Identities = 59/367 (16%), Positives = 114/367 (31%), Gaps = 51/367 (13%)

Query: 6   VAIIGLGPAGSALA---RKLAGK----MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSF 58
           V IIG GPAG++     + LA +    + VI  + K   G    +  C G+L+   +   
Sbjct: 485 VVIIGGGPAGTSCGIALKHLAKEKNIDINVILYEMKDFEGGIEHN-ECAGVLSHPIEHIM 543

Query: 59  -IRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEV 117
                +  P  ++           +               + R  FD ++      +   
Sbjct: 544 EDTLKIPFPWYLVKRDIPGYYLHANGQTITLEGNGEISYALRRIQFDAYLLQKAKEAGVT 603

Query: 118 YHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAI 177
              S    I    +K  +        +H +A  +VGA G      +        +    +
Sbjct: 604 VIKSKVTDIEIGREKIVIY----SETRHTSADVVVGAFGIEEGTHKLFESGTPYKSPKYL 659

Query: 178 QQWFAEKHPVPFYSCIFDNSITNCYSWSI-------------SKDGYFIFGGAY------ 218
                + HP   Y    D   T+ Y  +               K  ++    A       
Sbjct: 660 LSILTKFHPKGKY---HDLENTDGYIHAFLSSIKEIEFGAITPKADHYTINIAGAKISSK 716

Query: 219 PMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFI 278
            M +   +   + +    F+   G       C  + P++        D   +IG+AAG I
Sbjct: 717 SMDNFLQQSEVMNQLPECFKDALGHFDYHRGCFPVKPAK----NPFGDRYVIIGDAAGLI 772

Query: 279 SASSLEGISYALDSTDILRSVLLK---QPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAP 335
                +G++ A          ++         +T+Y+ +   +   L           A 
Sbjct: 773 RPFKGKGVNAACLMGIKAAETMMNVGISKRAFHTSYFNSFYDVIKDLP---------YAR 823

Query: 336 ALRKWIM 342
           A+R++I+
Sbjct: 824 AVRRFII 830



 Score = 73.6 bits (179), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 68/367 (18%), Positives = 124/367 (33%), Gaps = 48/367 (13%)

Query: 6   VAIIGLGPAGS-------ALARKLAGKMQVIALDKKHQCGTEGFS-KPCGGLLAPDAQRS 57
           +AIIG GPAGS        LA++L  K+ +  L  K          K C G+L+      
Sbjct: 14  IAIIGGGPAGSFFAHFALKLAKELNKKITIYILCGKDFIQKGPVGCKMCAGVLSETLIAK 73

Query: 58  FIRDGLTLPVDVIANPQIF-----SVKTVDVAASLTRNYQRSYININ----RH------- 101
             ++G+ LP   I N           + + +   L  +  R          R+       
Sbjct: 74  MEQEGIVLPTSRIQNEIDGYFFQSQERGISLHHPLPGHKPRIITIFRGGGPRYSLSDVNI 133

Query: 102 AFDLWMKSLIPASVEVYHDSLCRKIWREDD---KWHVIFRADGWEQHITARYLVGADGAN 158
           +FD ++ +   +       ++  +I   ++     ++++R +G  + I+    VGA G N
Sbjct: 134 SFDDFLLNHSASMGAKVLSAIVEEIELPENPQHLVNIVYREEGIRKKISVSLAVGAFGVN 193

Query: 159 -SMVRRHLYPDHQIRKYVAIQQWFAEKHPVPFY--------SCIFDNSITN-CYSWSISK 208
            S+ +R +   H  R+  +I+   AE      Y          IF   I    ++  I K
Sbjct: 194 TSLTKRIVGKKHGYREPRSIRTCNAELPLGRSYIRERFQRTIYIFSLGIKPIKFAALIPK 253

Query: 209 DGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ---FGKTVKSEKCTVLFPSRWQDFVCGK 265
           D Y            +       +     +     +        C    P          
Sbjct: 254 DDYVTVSLVGNEDITKAHLMQFIKHPRIRELLPEGWSLPENVCICFPKIPVAHAA-HPYS 312

Query: 266 DNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQPE---KLNTAYWRATRKLRL-- 320
           D   + G+A   IS +   GI  + +++ +                 AY+    KL    
Sbjct: 313 DRFVITGDA--SISRTYKNGIESSFETSRLAAYAAFYHGISERDFKEAYYTPALKLLAND 370

Query: 321 KLFGKIV 327
             +GK++
Sbjct: 371 NFYGKLI 377


>UniRef50_A5D6E0 Dehydrogenases n=4 Tax=Bacteria RepID=A5D6E0_PELTS
          Length = 432

 Score =  104 bits (258), Expect = 7e-21,   Method: Composition-based stats.
 Identities = 65/368 (17%), Positives = 120/368 (32%), Gaps = 47/368 (12%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           E F   ++G GPAGS  A  +A   ++V+ ++K    G++      GG +   A    I 
Sbjct: 3   EKFAAIVVGAGPAGSTAAYLMAKAGLEVLLIEKGAAPGSKNMF---GGRMYSHALNQVIP 59

Query: 61  DG-LTLPVDVIANPQIFSVKTVDVAASLT--------RNYQRSYININRHAFDLWMKSLI 111
                 PV+     +I ++ T D   S++          Y      + R  FD W+ +  
Sbjct: 60  GFWAEAPVERPVAKEIITLMTGDQCLSISIQDLSWTKPPYHYHSFTLLRAEFDAWLAAKA 119

Query: 112 PASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSM------VRRHL 165
             +  +    +        D   V  RA   E  + A  ++ ADG NS+      + R  
Sbjct: 120 EEAGAMLACGIRVDDLLIKDGRVVGIRA--GEDEMLADVVIAADGVNSLMAQKAGLARMF 177

Query: 166 YP-------DHQIRKYVAIQQWFAEKHPVPFYSCIFDNSITNCY-SWSISKDGYFIFGGA 217
            P          I+          +       + +F    T                   
Sbjct: 178 SPGQVATGVKQVIKLSPEEISRRFQLEGNNGAAQLFVGECTKGMQGGGFIYTNKDTISLG 237

Query: 218 YPMKDGQTRFTTLKEKMSAFQFQFGKTVKS--------EKCTVLFPSRWQD--FVCGKDN 267
             +K  + + T  K      +F+    ++         E    L P    D       D 
Sbjct: 238 LVIKAAELQKTQHKIADLVEEFKHNPHIRPLVEGGEVVEYSAHLVPEAGLDMMPQLYGDG 297

Query: 268 AFLIGEAAGFI--SASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGK 325
             + G+AAGF+      + G+ +A+ S       +++     N +      +  L  + K
Sbjct: 298 ILVAGDAAGFVLNLGYIVRGMDFAIASGQAAAQTVIEAARNNNFS------RQSLSQYAK 351

Query: 326 IVKSRCLT 333
           ++K   + 
Sbjct: 352 LLKESFVL 359


>UniRef50_C5CNW2 Tryptophan halogenase n=13 Tax=Proteobacteria RepID=C5CNW2_VARPS
          Length = 455

 Score =  103 bits (257), Expect = 8e-21,   Method: Composition-based stats.
 Identities = 61/365 (16%), Positives = 112/365 (30%), Gaps = 40/365 (10%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
           E  DV +IG GPAGS ++  LA + + + L +K            G  L P     F R 
Sbjct: 19  ESCDVLVIGGGPAGSTISALLAQQGRKVVLLEKEHHPRFHI----GESLLPANVELFDRL 74

Query: 62  GLTLPVDVIANPQIF--------SVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIP 112
           G+   V+ I  P+            ++    A        S   + R   D  + ++   
Sbjct: 75  GVRDQVEKIGMPKFGIEFVSPEHEHRSYVDFAEGWDKSLDSAWQVRRSELDELLFRNAAA 134

Query: 113 ASVEVYHDSLCRKIWREDDKWHVIFRA-DGWEQHITARYLVGADGANSMVRRHL-----Y 166
              +       R +  + +   V  +  DG  +   AR++V A G ++++          
Sbjct: 135 RGAQALEGCKVRDVAFDANGATVQAQMDDGARRSWRARFVVDATGRDTLLANKFRCKEKN 194

Query: 167 PDHQ---IRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSIS-KDGYFIFGGA---YP 219
           PDH    +  +    +    K       C F +     + W I   DG    G     Y 
Sbjct: 195 PDHNSTALFGHFTNAERLEGKKEGNISICWFAH----GWFWFIPLADGTTSVGAVCWPYY 250

Query: 220 MKDGQTRFTTLKEKMSAF-----QFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEA 274
           +K              A            T+  +         +       D   ++G+A
Sbjct: 251 LKTRDKPLKDFFYDTIALCPVLVDRLKHATLVDDAVHATGNFSYSSTHATGDRYLMLGDA 310

Query: 275 AGFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTA 334
             FI      G+  A+ S      ++    ++           +R      + K     +
Sbjct: 311 FTFIDPMFSSGVYLAMHSAFDGAGLVATALDRP-----AELAPVRENFEAMMRKGPREYS 365

Query: 335 PALRK 339
             + +
Sbjct: 366 WFIYR 370


>UniRef50_B5I9Q2 FAD dependent oxidoreductase, putative n=2 Tax=Aciduliprofundum
           boonei T469 RepID=B5I9Q2_9EURY
          Length = 375

 Score =  103 bits (257), Expect = 9e-21,   Method: Composition-based stats.
 Identities = 66/331 (19%), Positives = 116/331 (35%), Gaps = 40/331 (12%)

Query: 4   FDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +DVAI+G GP GS + +++A     VI  ++  + G       C GL + +      + G
Sbjct: 2   YDVAIVGAGPIGSFIGKEIASLGYNVIIFEEHSEIGNPSH---CSGLFSTNIFDIVGKIG 58

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPA-SVEVYHDS 121
           +  P        I++    D +     N +     ++R  FD  +  +  A   E++   
Sbjct: 59  ILHPAKKAV---IYAP---DGSKLRIGNDKVRGYVVDRVKFDRELAKMAGAKGAEIHLKE 112

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWF 181
             +K+   D            +    A+ +VGADG NS+VR+ +       K +   Q  
Sbjct: 113 RVKKVKYTD--------ISTSKGEYKAKIIVGADGINSIVRKEMGIGAP--KILGAAQII 162

Query: 182 AEKHPVPFYSCIFDNS--ITNCYSWSIS-KDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQ 238
           A  H       IF  S      ++W I   D     G    +   ++ +  LK+ M   +
Sbjct: 163 AHSHLDEDTVEIFIGSSIAPGFFAWRIPLFDDLAKIG----LASYKSSWLYLKKLMKKLK 218

Query: 239 FQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRS 298
            Q   ++      +    R            ++G+AAG + A+S  G+   L        
Sbjct: 219 VQP-LSISGGGIPINTVERTY-----ARGMLIVGDAAGQVKATSGGGVYPGLMCAKCAIK 272

Query: 299 VLLKQ------PEKLNTAYWRATRKLRLKLF 323
            +          E     Y    R    K  
Sbjct: 273 AIKDALERGDYSENALKNYETCWRNGIGKEL 303


Searching..................................................done


Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_A1AHM5 Protein cbrA n=54 Tax=Enterobacteriaceae RepID=C...   393   e-108
UniRef50_D2THX1 Putative uncharacterized protein n=4 Tax=Bacteri...   359   7e-98
UniRef50_B6ZQD5 Protein CbrA n=1 Tax=Escherichia coli O157:H7 st...   358   2e-97
UniRef50_C3KYD3 CbrA protein n=14 Tax=Bacteria RepID=C3KYD3_CLOB6     322   2e-86
UniRef50_B8FUH4 FAD dependent oxidoreductase n=3 Tax=Clostridial...   290   7e-77
UniRef50_UPI00019786F4 putative oxidoreductase n=1 Tax=Helicobac...   269   1e-70
UniRef50_Q7VFG9 Putative uncharacterized protein n=1 Tax=Helicob...   258   2e-67
UniRef50_C6JQS4 FAD dependent oxidoreductase n=1 Tax=Fusobacteri...   253   9e-66
UniRef50_D1RCG6 Geranylgeranyl reductase family protein n=1 Tax=...   246   9e-64
UniRef50_Q649G8 Geranylgeranyl reductase n=3 Tax=environmental s...   239   1e-61
UniRef50_B5W6L5 Geranylgeranyl reductase n=2 Tax=Arthrospira Rep...   235   1e-60
UniRef50_Q1IMS5 Geranylgeranyl reductase n=1 Tax=Candidatus Kori...   230   8e-59
UniRef50_O29786 Digeranylgeranylglycerophospholipid reductase n=...   230   8e-59
UniRef50_Q648X7 Geranylgeranyl reductase n=4 Tax=environmental s...   229   1e-58
UniRef50_Q11W52 Probable electron transfer flavoprotein n=1 Tax=...   228   3e-58
UniRef50_A5D4V1 Dehydrogenases n=1 Tax=Pelotomaculum thermopropi...   224   4e-57
UniRef50_A6QA88 Geranylgeranyl hydrogenase n=1 Tax=Sulfurovum sp...   223   6e-57
UniRef50_Q2NFZ1 Digeranylgeranylglycerophospholipid reductase 1 ...   222   2e-56
UniRef50_Q2RKB3 Geranylgeranyl reductase n=1 Tax=Moorella thermo...   221   2e-56
UniRef50_B3ECC8 Geranylgeranyl reductase n=3 Tax=Chlorobium RepI...   221   4e-56
UniRef50_B8HM17 Geranylgeranyl reductase n=1 Tax=Cyanothece sp. ...   220   7e-56
UniRef50_A6UWL1 Digeranylgeranylglycerophospholipid reductase n=...   219   1e-55
UniRef50_Q12YW2 Digeranylgeranylglycerophospholipid reductase 1 ...   218   2e-55
UniRef50_C6BUN1 Geranylgeranyl reductase n=1 Tax=Desulfovibrio s...   217   6e-55
UniRef50_Q2NER9 Digeranylgeranylglycerophospholipid reductase 3 ...   216   8e-55
UniRef50_C5A6E5 Digeranylgeranylglycerophospholipid reductase n=...   216   8e-55
UniRef50_UPI0001C15A6F geranylgeranyl reductase n=2 Tax=Nostocac...   216   9e-55
UniRef50_Q8DGN7 Tlr2279 protein n=5 Tax=Cyanobacteria RepID=Q8DG...   216   1e-54
UniRef50_D2B4C1 Geranylgeranyl reductase n=4 Tax=Actinomycetales...   215   1e-54
UniRef50_P96800 Uncharacterized protein Mbar_A1602 n=1 Tax=Metha...   215   2e-54
UniRef50_C9RJJ2 Geranylgeranyl reductase n=1 Tax=Fibrobacter suc...   215   2e-54
UniRef50_A8URP5 Putative uncharacterized protein n=2 Tax=Aquific...   215   2e-54
UniRef50_C6PBK9 Geranylgeranyl reductase n=1 Tax=Thermoanaerobac...   215   2e-54
UniRef50_O26377 Digeranylgeranylglycerophospholipid reductase 1 ...   214   4e-54
UniRef50_Q6L0M1 Digeranylgeranylglycerophospholipid reductase n=...   213   7e-54
UniRef50_D2RHK2 Geranylgeranyl reductase n=2 Tax=Archaeoglobacea...   213   8e-54
UniRef50_A0LRI0 Geranylgeranyl reductase n=38 Tax=Actinomycetale...   213   1e-53
UniRef50_B3QNV5 Geranylgeranyl reductase n=4 Tax=Chlorobiaceae R...   212   2e-53
UniRef50_O27753 Digeranylgeranylglycerophospholipid reductase 2 ...   211   2e-53
UniRef50_A6CDB5 Geranylgeranyl reductase n=1 Tax=Planctomyces ma...   211   3e-53
UniRef50_B3QWR4 Geranylgeranyl reductase n=1 Tax=Chloroherpeton ...   211   4e-53
UniRef50_Q8TUV8 Digeranylgeranylglycerophospholipid reductase 2 ...   210   5e-53
UniRef50_B4CWA5 Monooxygenase FAD-binding n=1 Tax=Chthoniobacter...   209   1e-52
UniRef50_C9R7U9 Geranylgeranyl reductase n=1 Tax=Ammonifex degen...   209   1e-52
UniRef50_B9L6H5 Geranylgeranyl hydrogenase n=2 Tax=Nautiliaceae ...   209   2e-52
UniRef50_A0QR89 Geranylgeranyl reductase n=7 Tax=Mycobacterium R...   207   5e-52
UniRef50_Q6L1J9 Geranylgeranyl hydrogenase n=3 Tax=Thermoplasmat...   206   9e-52
UniRef50_Q12X19 Geranylgeranyl reductase n=1 Tax=Methanococcoide...   205   1e-51
UniRef50_A5D5E0 Dehydrogenases n=1 Tax=Pelotomaculum thermopropi...   205   2e-51
UniRef50_B1L612 Geranylgeranyl reductase n=1 Tax=Candidatus Kora...   205   3e-51
UniRef50_A6BZI3 Probable alkylhalidase n=1 Tax=Planctomyces mari...   204   3e-51
UniRef50_Q4JN54 Putative uncharacterized protein n=1 Tax=uncultu...   203   7e-51
UniRef50_D2QMD3 Monooxygenase FAD-binding protein n=5 Tax=Bacter...   203   9e-51
UniRef50_A1U6D3 Geranylgeranyl reductase n=2 Tax=Marinobacter Re...   203   1e-50
UniRef50_D1YYN0 Geranylgeranyl reductase n=1 Tax=Methanocella pa...   202   1e-50
UniRef50_UPI000038E1B1 geranylgeranyl hydrogenase n=1 Tax=Ferrop...   200   5e-50
UniRef50_A1RY40 Geranylgeranyl reductase n=1 Tax=Thermofilum pen...   200   5e-50
UniRef50_D1CDE0 Geranylgeranyl reductase n=1 Tax=Thermobaculum t...   200   6e-50
UniRef50_C0ZA99 Electron transfer flavoprotein-quinone oxidoredu...   200   6e-50
UniRef50_Q3A1Y0 Flavoprotein-containing dehydrogenase n=1 Tax=Pe...   199   1e-49
UniRef50_C3XVJ7 Putative uncharacterized protein n=1 Tax=Branchi...   199   2e-49
UniRef50_A8UYA2 Putative uncharacterized protein n=2 Tax=Aquific...   198   2e-49
UniRef50_A3HTX2 FAD dependent oxidoreductase, putative n=1 Tax=A...   198   2e-49
UniRef50_P26172 Geranylgeranyl diphosphate reductase n=34 Tax=Ba...   198   2e-49
UniRef50_B8G4M6 Geranylgeranyl reductase n=6 Tax=Chloroflexaceae...   198   2e-49
UniRef50_B1L6M6 Geranylgeranyl reductase n=1 Tax=Candidatus Kora...   198   3e-49
UniRef50_Q0W1J4 Predicted FAD-dependent oxidoreductase n=2 Tax=E...   198   3e-49
UniRef50_B3QZ41 Geranylgeranyl reductase n=12 Tax=Chlorobiaceae ...   198   3e-49
UniRef50_D1UBL8 Geranylgeranyl reductase n=1 Tax=Desulfovibrio a...   197   4e-49
UniRef50_C8X2V2 Geranylgeranyl reductase n=1 Tax=Desulfohalobium...   197   6e-49
UniRef50_UPI0001C42077 geranylgeranyl reductase family protein n...   197   7e-49
UniRef50_D2VJZ4 CMF receptor CMFR1 n=1 Tax=Naegleria gruberi Rep...   196   8e-49
UniRef50_UPI000050FC1D geranylgeranyl reductase n=1 Tax=Brevibac...   195   2e-48
UniRef50_Q1PX22 Putative uncharacterized protein n=1 Tax=Candida...   193   9e-48
UniRef50_B4AWE1 Monooxygenase FAD-binding n=1 Tax=Cyanothece sp....   193   1e-47
UniRef50_D1JEF0 Putative uncharacterized protein n=1 Tax=uncultu...   192   2e-47
UniRef50_B5YGK5 Geranylgeranyl hydrogenase, putative n=1 Tax=The...   192   2e-47
UniRef50_Q58915 Uncharacterized protein MJ1520 n=11 Tax=Methanoc...   192   2e-47
UniRef50_B4D801 Tryptophan halogenase n=1 Tax=Chthoniobacter fla...   192   2e-47
UniRef50_A2BVI2 NAD binding site n=7 Tax=Prochlorococcus marinus...   191   2e-47
UniRef50_B0JID7 Geranylgeranyl reductase n=8 Tax=Cyanobacteria R...   191   3e-47
UniRef50_Q8DJ25 Tll1404 protein n=7 Tax=Cyanobacteria RepID=Q8DJ...   191   3e-47
UniRef50_A5FDA0 FAD dependent oxidoreductase n=2 Tax=Bacteroidet...   191   3e-47
UniRef50_B4U8N3 Geranylgeranyl reductase n=1 Tax=Hydrogenobaculu...   191   3e-47
UniRef50_A9A398 Geranylgeranyl reductase n=4 Tax=Thaumarchaeota ...   191   3e-47
UniRef50_D1CHF7 Geranylgeranyl reductase n=1 Tax=Thermobaculum t...   190   7e-47
UniRef50_Q1VX49 FAD dependent oxidoreductase, putative n=1 Tax=P...   189   9e-47
UniRef50_Q0BPD7 Dehydrogenases (Flavoproteins) n=1 Tax=Granuliba...   189   2e-46
UniRef50_A0B5F9 Geranylgeranyl reductase n=1 Tax=Methanosaeta th...   189   2e-46
UniRef50_Q3A4T4 Dehydrogenase, flavoprotein containing n=1 Tax=P...   189   2e-46
UniRef50_A8JAG1 Predicted protein n=1 Tax=Chlamydomonas reinhard...   188   2e-46
UniRef50_A3CSH0 Geranylgeranyl reductase n=1 Tax=Methanoculleus ...   188   2e-46
UniRef50_B8GFT3 Geranylgeranyl reductase n=1 Tax=Methanosphaerul...   188   3e-46
UniRef50_C4RL56 Alkylhalidase cmlS n=1 Tax=Micromonospora sp. AT...   188   4e-46
UniRef50_UPI0001744EC4 Putative Dehyrogenase n=1 Tax=Verrucomicr...   187   5e-46
UniRef50_Q6ALA8 Related to dehydrogenases (Flavoproteins) n=1 Ta...   187   6e-46
UniRef50_Q0Q5F4 Halogenase n=8 Tax=Actinomycetales RepID=Q0Q5F4_...   187   6e-46
UniRef50_Q2S264 FAD dependent oxidoreductase, putative n=1 Tax=S...   187   6e-46
UniRef50_A7BBW6 Putative uncharacterized protein n=1 Tax=Actinom...   186   8e-46
UniRef50_Q9U641 Conditioned medium factor receptor 1 n=1 Tax=Dic...   186   1e-45
UniRef50_C6XUK6 FAD dependent oxidoreductase n=1 Tax=Pedobacter ...   186   1e-45
UniRef50_A0M1U0 Oxidoreductase n=2 Tax=Flavobacteriaceae RepID=A...   186   1e-45
UniRef50_B4CVZ2 Geranylgeranyl reductase n=1 Tax=Chthoniobacter ...   185   2e-45
UniRef50_A8LAV2 Geranylgeranyl reductase n=5 Tax=Actinomycetales...   185   3e-45
UniRef50_C9RKL4 FAD dependent oxidoreductase n=1 Tax=Fibrobacter...   184   3e-45
UniRef50_UPI0000D53425 oxidoreductase n=1 Tax=Psychroflexus torq...   184   3e-45
UniRef50_B9M019 FAD dependent oxidoreductase n=1 Tax=Geobacter s...   184   3e-45
UniRef50_D1UBF5 Geranylgeranyl reductase n=1 Tax=Desulfovibrio a...   184   4e-45
UniRef50_B4UA54 Geranylgeranyl reductase n=1 Tax=Hydrogenobaculu...   184   4e-45
UniRef50_Q3A9B4 FixC protein n=1 Tax=Carboxydothermus hydrogenof...   184   5e-45
UniRef50_A3XIL9 Putative uncharacterized protein n=1 Tax=Leeuwen...   183   1e-44
UniRef50_B9XPY2 Tryptophan halogenase n=3 Tax=Verrucomicrobiales...   182   1e-44
UniRef50_D2R1S0 Tryptophan halogenase n=7 Tax=Planctomycetaceae ...   182   1e-44
UniRef50_Q26DN3 Putative uncharacterized protein n=1 Tax=Flavoba...   182   2e-44
UniRef50_A3CW88 Geranylgeranyl reductase n=1 Tax=Methanoculleus ...   182   2e-44
UniRef50_C5CNW2 Tryptophan halogenase n=13 Tax=Proteobacteria Re...   182   2e-44
UniRef50_Q0HQD9 Monooxygenase, FAD-binding protein n=94 Tax=cell...   182   2e-44
UniRef50_Q0SFD6 Pentachlorophenol monooxygenase n=6 Tax=Actinomy...   182   2e-44
UniRef50_A7KH01 NapH2 n=10 Tax=Actinomycetales RepID=A7KH01_9ACTO     181   4e-44
UniRef50_UPI00018742EF geranylgeranyl reductase n=1 Tax=Coryneba...   181   4e-44
UniRef50_A3EQU0 Geranylgeranyl reductase family protein n=2 Tax=...   180   6e-44
UniRef50_Q8KY40 RubN n=2 Tax=Streptomyces RepID=Q8KY40_STRCU          180   6e-44
UniRef50_B5YDH3 FAD dependent oxidoreductase, putative n=2 Tax=D...   179   1e-43
UniRef50_Q31QX9 Geranylgeranyl reductase n=2 Tax=Synechococcus e...   179   1e-43
UniRef50_A3JWR6 Geranylgeranyl reductase n=1 Tax=Rhodobacterales...   179   1e-43
UniRef50_C4L154 Monooxygenase FAD-binding n=1 Tax=Exiguobacteriu...   179   1e-43
UniRef50_Q46C42 Geranylgeranyl reductase n=5 Tax=Methanosarcina ...   179   2e-43
UniRef50_C6VXB5 FAD dependent oxidoreductase n=1 Tax=Dyadobacter...   179   2e-43
UniRef50_Q2RLB4 Geranylgeranyl reductase n=1 Tax=Moorella thermo...   179   2e-43
UniRef50_B0TPS5 Tryptophan halogenase n=12 Tax=Proteobacteria Re...   178   3e-43
UniRef50_D1RDY9 FAD dependent oxidoreductase domain protein n=1 ...   178   3e-43
UniRef50_A8M2V9 Geranylgeranyl reductase n=5 Tax=Actinomycetales...   178   3e-43
UniRef50_Q3JCF5 Geranylgeranyl reductase n=2 Tax=Nitrosococcus o...   177   4e-43
UniRef50_Q8KLM2 StaK n=1 Tax=Streptomyces toyocaensis RepID=Q8KL...   177   5e-43
UniRef50_Q2JG94 Putative uncharacterized protein n=1 Tax=Frankia...   177   7e-43
UniRef50_A8ME14 Geranylgeranyl reductase n=1 Tax=Caldivirga maqu...   177   7e-43
UniRef50_D2C3Q7 Electron-transferring-flavoprotein dehydrogenase...   176   8e-43
UniRef50_Q4MV03 Geranylgeranyl hydrogenase BchP, putative n=12 T...   176   8e-43
UniRef50_C4XQT1 Geranylgeranyl reductase n=2 Tax=Desulfovibrio R...   176   1e-42
UniRef50_C8VZJ8 Electron-transferring-flavoproteindehydrogenase ...   176   1e-42
UniRef50_D1BBC7 Geranylgeranyl reductase family protein n=11 Tax...   176   1e-42
UniRef50_B4WHJ4 Putative uncharacterized protein n=1 Tax=Synecho...   176   1e-42
UniRef50_C7PJY7 Geranylgeranyl reductase n=1 Tax=Chitinophaga pi...   176   2e-42
UniRef50_A4YEK4 Geranylgeranyl reductase n=12 Tax=Sulfolobaceae ...   175   2e-42
UniRef50_D1SGH3 Monooxygenase FAD-binding n=12 Tax=Actinomycetal...   175   2e-42
UniRef50_A8THG7 Geranylgeranyl reductase n=1 Tax=Methanococcus v...   175   2e-42
UniRef50_Q095S4 Pentachlorophenol 4-monooxygenase n=5 Tax=Bacter...   174   3e-42
UniRef50_Q9CA67 Geranylgeranyl diphosphate reductase, chloroplas...   174   3e-42
UniRef50_A3DPJ1 Geranylgeranyl reductase n=2 Tax=Desulfurococcac...   174   3e-42
UniRef50_Q24QW7 Putative uncharacterized protein n=1 Tax=Desulfi...   174   3e-42
UniRef50_A3V9M1 Geranylgeranyl reductase n=1 Tax=Rhodobacterales...   174   4e-42
UniRef50_A2BM78 Predicted Dehydrogenase n=1 Tax=Hyperthermus but...   174   5e-42
UniRef50_C6CUN6 Monooxygenase FAD-binding n=1 Tax=Paenibacillus ...   174   6e-42
UniRef50_C8SW54 Monooxygenase FAD-binding n=1 Tax=Mesorhizobium ...   173   6e-42
UniRef50_Q9AL91 Alkylhalidase CmlS n=3 Tax=Actinomycetales RepID...   173   7e-42
UniRef50_C6VW94 Tryptophan halogenase n=1 Tax=Dyadobacter fermen...   173   8e-42
UniRef50_Q82R48 Putative FAD-binding monooxygenase n=1 Tax=Strep...   173   1e-41
UniRef50_B1L7J1 Dehydrogenase (Flavoprotein) n=1 Tax=Candidatus ...   173   1e-41
UniRef50_B1YHN9 Monooxygenase FAD-binding n=1 Tax=Exiguobacteriu...   172   2e-41
UniRef50_A1RZG7 Geranylgeranyl reductase n=1 Tax=Thermofilum pen...   172   2e-41
UniRef50_C3NB54 FAD dependent oxidoreductase n=12 Tax=Sulfolobac...   172   2e-41
UniRef50_C7M500 Tryptophan halogenase n=4 Tax=Flavobacteriaceae ...   171   4e-41
UniRef50_D1X0J5 Geranylgeranyl reductase n=1 Tax=Streptomyces sp...   171   4e-41
UniRef50_C9N331 Geranylgeranyl reductase n=3 Tax=Streptomyces Re...   171   5e-41
UniRef50_C0DS67 Putative uncharacterized protein n=2 Tax=Neisser...   170   5e-41
UniRef50_C8SAI9 Geranylgeranyl reductase n=1 Tax=Ferroglobus pla...   170   7e-41
UniRef50_UPI0001AEE709 putative oxidoreductase n=1 Tax=Streptomy...   170   7e-41
UniRef50_Q0R4P7 ChlB4 n=8 Tax=Bacteria RepID=Q0R4P7_STRAT             170   8e-41
UniRef50_Q4V217 Possible monooxygenase n=1 Tax=Bacillus cereus E...   170   8e-41
UniRef50_O26821 Conserved protein n=1 Tax=Methanothermobacter th...   169   9e-41
UniRef50_C7PZI2 Tryptophan halogenase n=2 Tax=Actinomycetales Re...   169   1e-40
UniRef50_D0LR77 Monooxygenase FAD-binding protein n=1 Tax=Halian...   169   1e-40
UniRef50_B8FXK4 Electron-transferring-flavoprotein dehydrogenase...   169   2e-40
UniRef50_Q4ZTV6 Flavoprotein monooxygenase:Monooxygenase, FAD-bi...   169   2e-40
UniRef50_Q5FR44 Putative oxidoreductase n=1 Tax=Gluconobacter ox...   169   2e-40
UniRef50_Q31RA2 Geranylgeranyl reductase n=13 Tax=cellular organ...   168   3e-40
UniRef50_A8ABI3 Geranylgeranyl reductase n=1 Tax=Ignicoccus hosp...   168   3e-40
UniRef50_A8M3W4 Geranylgeranyl reductase n=1 Tax=Salinispora are...   168   3e-40
UniRef50_C0VR61 Geranylgeranyl reductase n=2 Tax=Corynebacterium...   168   4e-40
UniRef50_Q9HLA3 FixC protein related n=2 Tax=Thermoplasma RepID=...   168   4e-40
UniRef50_A1KG38 Possible oxidoreductase n=11 Tax=Mycobacterium R...   167   4e-40
UniRef50_Q2FLI3 Geranylgeranyl reductase n=1 Tax=Methanospirillu...   167   4e-40
UniRef50_C6W802 Monooxygenase FAD-binding n=1 Tax=Actinosynnema ...   167   5e-40
UniRef50_A4JL31 Monooxygenase, FAD-binding n=3 Tax=Burkholderia ...   167   5e-40
UniRef50_B2SJD1 Hydroxylase n=12 Tax=Xanthomonas RepID=B2SJD1_XANOP   167   6e-40
UniRef50_Q8GHB4 Putative halogenase n=1 Tax=Streptomyces roseoch...   167   7e-40
UniRef50_Q21HW5 Monooxygenase, FAD-binding n=1 Tax=Saccharophagu...   166   7e-40
UniRef50_A8L4I1 Monooxygenase FAD-binding n=7 Tax=Actinomycetale...   166   8e-40
UniRef50_C6W874 Tryptophan halogenase n=2 Tax=Actinosynnema RepI...   166   1e-39
UniRef50_D1C5T7 Monooxygenase FAD-binding protein n=2 Tax=Thermo...   166   1e-39
UniRef50_Q0SF87 Possible dehydrogenase n=23 Tax=Actinomycetales ...   166   1e-39
UniRef50_UPI0001745691 hypothetical protein VspiD_29115 n=1 Tax=...   166   1e-39
UniRef50_D2PLJ7 Monooxygenase FAD-binding protein n=10 Tax=Actin...   166   1e-39
UniRef50_C5C803 2-polyprenyl-6-methoxyphenol hydroxylase-like ox...   165   2e-39
UniRef50_O29239 Bacteriochlorophyll synthase, 43 kDa subunit (Ch...   165   2e-39
UniRef50_D2XDX8 AzicO4 n=2 Tax=Kibdelosporangium sp. MJ126-NF4 R...   165   2e-39
UniRef50_A1T3S9 Geranylgeranyl reductase n=10 Tax=Actinomycetale...   165   2e-39
UniRef50_D2RGA8 Dehydrogenase (Flavoprotein)-like protein n=1 Ta...   165   2e-39
UniRef50_A6G4M1 Putative halogenase n=1 Tax=Plesiocystis pacific...   164   4e-39
UniRef50_UPI000178A157 monooxygenase FAD-binding protein n=1 Tax...   164   4e-39
UniRef50_B8GUG5 Geranylgeranyl reductase n=5 Tax=Gammaproteobact...   164   4e-39
UniRef50_B8ES76 Monooxygenase FAD-binding n=1 Tax=Methylocella s...   164   4e-39
UniRef50_C0GUA1 Geranylgeranyl reductase n=1 Tax=Desulfonatronos...   164   4e-39
UniRef50_C6HZ38 Geranylgeranyl reductase n=1 Tax=Leptospirillum ...   164   6e-39
UniRef50_A1HMV3 FAD dependent oxidoreductase n=1 Tax=Thermosinus...   164   6e-39
UniRef50_A5G7E3 FAD dependent oxidoreductase n=2 Tax=Geobacter R...   164   6e-39
UniRef50_A8LZN8 Tryptophan halogenase n=2 Tax=Micromonosporaceae...   163   8e-39
UniRef50_Q467V5 Putative uncharacterized protein n=3 Tax=Methano...   163   9e-39
UniRef50_Q2JXT2 2-octaprenyl-6-methoxyphenol hydroxylase n=2 Tax...   163   9e-39
UniRef50_A4JRJ4 Tryptophan halogenase n=6 Tax=Proteobacteria Rep...   163   1e-38
UniRef50_A7GPR1 FAD dependent oxidoreductase n=1 Tax=Bacillus cy...   163   1e-38
UniRef50_B5HTB3 Alkylhalidase n=3 Tax=Actinomycetales RepID=B5HT...   163   1e-38
UniRef50_Q6EVQ8 Putative FAD-dependent monooxygenase n=1 Tax=Yer...   163   1e-38
UniRef50_Q0RKB9 Putative 3-(3-hydroxy-phenyl)propionate hydroxyl...   162   2e-38
UniRef50_B5HZJ0 Pentachlorophenol 4-monooxygenase n=2 Tax=Strept...   162   2e-38
UniRef50_B5Y9L9 FAD binding domain, putative n=1 Tax=Coprothermo...   162   2e-38
UniRef50_D0L4V5 Geranylgeranyl reductase n=6 Tax=Actinomycetales...   162   2e-38
UniRef50_B8G0W1 Electron-transferring-flavoprotein dehydrogenase...   162   2e-38
UniRef50_B9XGA7 Tryptophan halogenase n=1 Tax=bacterium Ellin514...   162   2e-38
UniRef50_C7M2T6 Geranylgeranyl reductase n=1 Tax=Acidimicrobium ...   161   2e-38
UniRef50_B4V6H8 Pentachlorophenol 4-monooxygenase n=6 Tax=Strept...   161   2e-38
UniRef50_A3MV77 Geranylgeranyl reductase n=5 Tax=Thermoproteacea...   161   3e-38
UniRef50_C6A374 Geranylgeranyl hydrogenase n=9 Tax=Thermococcace...   161   3e-38
UniRef50_D2AYA7 Putative uncharacterized protein n=1 Tax=Strepto...   161   4e-38
UniRef50_Q2FUA4 Digeranylgeranylglycerophospholipid reductase n=...   161   5e-38
UniRef50_B9LNF2 Geranylgeranyl reductase n=11 Tax=Halobacteriace...   160   6e-38
UniRef50_UPI0001787E07 monooxygenase FAD-binding protein n=1 Tax...   160   7e-38
UniRef50_C5CID7 FAD dependent oxidoreductase n=1 Tax=Kosmotoga o...   160   8e-38
UniRef50_C7DGR0 Geranylgeranyl reductase n=1 Tax=Candidatus Micr...   159   1e-37
UniRef50_A4X5N9 Monooxygenase, FAD-binding n=3 Tax=Micromonospor...   159   1e-37
UniRef50_Q7USU8 Probable alkylhalidase homolog n=1 Tax=Rhodopire...   159   1e-37
UniRef50_C3JMW7 Monooxygenase, FAD-binding protein n=2 Tax=Rhodo...   159   1e-37
UniRef50_B5I9Q2 FAD dependent oxidoreductase, putative n=2 Tax=A...   159   1e-37
UniRef50_Q7UYT6 Probable alkylhalidase n=1 Tax=Rhodopirellula ba...   159   1e-37
UniRef50_A0B6Y7 Geranylgeranyl reductase n=1 Tax=Methanosaeta th...   159   1e-37
UniRef50_P26484 Protein fixC n=50 Tax=Bacteria RepID=FIXC_AZOC5       159   1e-37
UniRef50_B1MM05 Putative FAD-binding monooxygenase n=1 Tax=Mycob...   159   2e-37
UniRef50_A0B730 Geranylgeranyl reductase n=1 Tax=Methanosaeta th...   159   2e-37
UniRef50_C6WHE7 Monooxygenase FAD-binding n=2 Tax=Actinomycetale...   158   2e-37
UniRef50_Q08YP8 Monooxygenase family protein n=1 Tax=Stigmatella...   158   2e-37
UniRef50_A8MAE2 Geranylgeranyl reductase n=6 Tax=Thermoproteacea...   158   2e-37
UniRef50_A8M0H4 Tryptophan halogenase n=130 Tax=Bacteria RepID=A...   158   3e-37
UniRef50_Q30ZB0 Geranylgeranyl reductase n=1 Tax=Desulfovibrio d...   158   3e-37
UniRef50_Q1AWH0 Geranylgeranyl reductase n=1 Tax=Rubrobacter xyl...   158   4e-37
UniRef50_B7RS31 FAD binding domain protein n=1 Tax=Roseobacter s...   158   4e-37
UniRef50_Q1QK25 Monooxygenase, FAD-binding n=2 Tax=Nitrobacter R...   157   5e-37
UniRef50_C5V9R0 FAD-linked oxidoreductase n=2 Tax=Corynebacteriu...   157   5e-37

Sequences not found previously or not previously below threshold:

UniRef50_Q11R94 Flavoprotein/dehydrogenase n=1 Tax=Cytophaga hut...   164   3e-39
UniRef50_C6XP81 Monooxygenase FAD-binding n=1 Tax=Hirschia balti...   159   2e-37
UniRef50_O07561 Uncharacterized aromatic compound monooxygenase ...   158   3e-37

>UniRef50_A1AHM5 Protein cbrA n=54 Tax=Enterobacteriaceae RepID=CBRA_ECOK1
          Length = 366

 Score =  393 bits (1010), Expect = e-108,   Method: Composition-based stats.
 Identities = 347/354 (98%), Positives = 350/354 (98%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQ GTEGFSKPCGGLLAPDAQRSFIR
Sbjct: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQHGTEGFSKPCGGLLAPDAQRSFIR 60

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD 120
           DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD
Sbjct: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD 120

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW 180
           SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW
Sbjct: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW 180

Query: 181 FAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ 240
           FAEKHPVPFYSCIFDN+IT+CYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ
Sbjct: 181 FAEKHPVPFYSCIFDNAITDCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ 240

Query: 241 FGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVL 300
           FGK VKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDS +ILRSVL
Sbjct: 241 FGKAVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSAEILRSVL 300

Query: 301 LKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAHIPQLKD 354
           LK PEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAHIPQLKD
Sbjct: 301 LKLPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAHIPQLKD 354


>UniRef50_D2THX1 Putative uncharacterized protein n=4 Tax=Bacteria
           RepID=D2THX1_CITRO
          Length = 380

 Score =  359 bits (923), Expect = 7e-98,   Method: Composition-based stats.
 Identities = 289/354 (81%), Positives = 317/354 (89%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           MEHFDVAIIGLGPAG+ALARKL+GKMQVIALDKK QCG EGF+KPCGGLLAPDAQR+FIR
Sbjct: 1   MEHFDVAIIGLGPAGAALARKLSGKMQVIALDKKRQCGNEGFTKPCGGLLAPDAQRAFIR 60

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD 120
           DGLTLPVDVIANPQIFSVKT+DV ASL RNYQRSYININRHAFDLW+KSLIP  V VYHD
Sbjct: 61  DGLTLPVDVIANPQIFSVKTIDVEASLERNYQRSYININRHAFDLWLKSLIPDDVRVYHD 120

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW 180
           SLCRKIWRE+DKWH+IFRADG EQ +T RYLVGADGANS+VRR+LYP HQIRKYVAIQQW
Sbjct: 121 SLCRKIWREEDKWHIIFRADGQEQKVTTRYLVGADGANSLVRRYLYPQHQIRKYVAIQQW 180

Query: 181 FAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ 240
           FAE HPVPFYSCIFDN+IT+CYSWSISKDGYFIFGGAYPMKDGQ RF  LK KM AFQF+
Sbjct: 181 FAESHPVPFYSCIFDNAITDCYSWSISKDGYFIFGGAYPMKDGQARFEALKAKMEAFQFR 240

Query: 241 FGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVL 300
           FG  +KSEKCTVLFPSRW+DFVCGKDNAFLIGEAAGFISASSLEGISYALDS D L +VL
Sbjct: 241 FGNPLKSEKCTVLFPSRWKDFVCGKDNAFLIGEAAGFISASSLEGISYALDSADRLNAVL 300

Query: 301 LKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAHIPQLKD 354
            +     N+AY + TR+LR+KL+GKI+KSR LT+   RK +M+SGVAHIP  +D
Sbjct: 301 TRHAADKNSAYRKVTRQLRIKLYGKILKSRILTSALTRKRVMQSGVAHIPLAQD 354


>UniRef50_B6ZQD5 Protein CbrA n=1 Tax=Escherichia coli O157:H7 str. TW14588
           RepID=B6ZQD5_ECO57
          Length = 374

 Score =  358 bits (919), Expect = 2e-97,   Method: Composition-based stats.
 Identities = 318/330 (96%), Positives = 323/330 (97%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQ GTEGFSKPCGGLLAPDAQRSFIR
Sbjct: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQHGTEGFSKPCGGLLAPDAQRSFIR 60

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD 120
           DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD
Sbjct: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD 120

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW 180
           SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRR+LYPDHQIRKYVAIQQW
Sbjct: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRYLYPDHQIRKYVAIQQW 180

Query: 181 FAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ 240
           FAEKHPVPFYSCIFDN+IT+CYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ
Sbjct: 181 FAEKHPVPFYSCIFDNAITDCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ 240

Query: 241 FGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVL 300
           FGK VKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDS +ILRSVL
Sbjct: 241 FGKAVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSAEILRSVL 300

Query: 301 LKQPEKLNTAYWRATRKLRLKLFGKIVKSR 330
           LKQPEK+N AYW ATRKLRLKLFGKIVK  
Sbjct: 301 LKQPEKINAAYWHATRKLRLKLFGKIVKIS 330


>UniRef50_C3KYD3 CbrA protein n=14 Tax=Bacteria RepID=C3KYD3_CLOB6
          Length = 364

 Score =  322 bits (825), Expect = 2e-86,   Method: Composition-based stats.
 Identities = 185/349 (53%), Positives = 248/349 (71%), Gaps = 1/349 (0%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           +  +D+AIIGLGP+GS LA+ L+ K +VIA+DKK+    +GF KPCGGLL+ DAQ++  +
Sbjct: 6   ISTYDIAIIGLGPSGSVLAQLLSKKHKVIAIDKKNSI-EKGFKKPCGGLLSSDAQKALAK 64

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD 120
             +TLP DV+ +PQIF+VKT+++  +L R YQR YIN++RH FDLW+KSLIP  VEVY +
Sbjct: 65  LDITLPKDVMVDPQIFAVKTIELKNALIRYYQRFYINLDRHKFDLWLKSLIPNHVEVYSN 124

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW 180
           S C  + +  + + V F   G +Q I  +YLVGADGANS+VRR LYP  +IR Y++IQQW
Sbjct: 125 SYCSSVEKIPEGYRVTFYEKGVKQVIITKYLVGADGANSLVRRSLYPKKKIRTYMSIQQW 184

Query: 181 FAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ 240
           F+E H  PFYSCIFD   T+C SWSISKD  FIFGGA+P+ + + RF   K+K+    F+
Sbjct: 185 FSETHDNPFYSCIFDLENTDCCSWSISKDNKFIFGGAFPIHNSRKRFENQKKKLEKIGFR 244

Query: 241 FGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVL 300
           FGK +K+E C VL PS + DF CGK+NAFL+GEAAGFIS SSLEGIS A++S  +L  VL
Sbjct: 245 FGKPIKTEACMVLRPSAFYDFCCGKENAFLVGEAAGFISPSSLEGISSAINSARVLSEVL 304

Query: 301 LKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAHI 349
               +  N  YW  T  +RLK+F K++K   +  P LRK +++SG+  I
Sbjct: 305 NTHSKDPNKKYWLKTFNIRLKIFLKLLKCPFMYNPFLRKLVLKSGLKSI 353


>UniRef50_B8FUH4 FAD dependent oxidoreductase n=3 Tax=Clostridiales
           RepID=B8FUH4_DESHD
          Length = 356

 Score =  290 bits (742), Expect = 7e-77,   Method: Composition-based stats.
 Identities = 132/351 (37%), Positives = 204/351 (58%), Gaps = 5/351 (1%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFS---KPCGGLLAPDAQRSFIR 60
           +DV IIG GPAGS+LAR +  K +V+ +DK+        +   K CGGLLAPDAQ+   +
Sbjct: 2   YDVLIIGAGPAGSSLARLIGDKYKVLLIDKRDLANENPHNLAGKCCGGLLAPDAQKMIAK 61

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD 120
            GL +P D++ NPQ+F+V+T+D+  +L R YQR Y+N++R  FD W+ S++P  V+   +
Sbjct: 62  LGLGIPKDILVNPQLFAVRTIDLTNNLERLYQRFYLNMDREKFDRWLVSILPKKVDKKFN 121

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPD-HQIRKYVAIQQ 179
           ++ +        + V +  +G E     R ++GADGA S +RR L  D +   KY+AIQ+
Sbjct: 122 AVFKDFVEIPGGYEVKYIHNGQEISAKTRVIIGADGAFSKLRRFLNQDINGPEKYIAIQE 181

Query: 180 WFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAY-PMKDGQTRFTTLKEKMSAFQ 238
           W+   H VP+++ IFD  I++ YSW I K+ Y + G A  P +  + ++  LK K++   
Sbjct: 182 WYECPHHVPYFTAIFDEEISDFYSWIIPKENYLLLGSALKPKEKAREKYELLKTKLTQRG 241

Query: 239 FQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRS 298
           F F   +++E   +  P +   F  G+D+  L+GEAAG IS SS EGISYAL S+  L  
Sbjct: 242 FNFDNKIRTEGAYLYRPKKVSQFYAGRDSIALVGEAAGGISPSSAEGISYALKSSAYLAQ 301

Query: 299 VLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAHI 349
            L +  +     Y    + ++L L  K +KS  +  P LR+  M+SG+  I
Sbjct: 302 SLEEGIDGFLDRYKLKVKGIKLNLLLKNLKSPAMYNPLLRQLAMKSGLQSI 352


>UniRef50_UPI00019786F4 putative oxidoreductase n=1 Tax=Helicobacter cinaedi CCUG 18818
           RepID=UPI00019786F4
          Length = 389

 Score =  269 bits (688), Expect = 1e-70,   Method: Composition-based stats.
 Identities = 156/366 (42%), Positives = 216/366 (59%), Gaps = 19/366 (5%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGT---EGFSKPCGGLLAPDAQRSF 58
             FD+AIIGLG AGS LA  L   ++VIA+DKK   G    E F KPCGGLL+   Q++F
Sbjct: 15  GEFDIAIIGLGVAGSNLASLLQSHLKVIAIDKKDSSGDCFDESFHKPCGGLLSEGGQKAF 74

Query: 59  IRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVY 118
              GL LP  ++  PQIF++ T+D         Q+ YIN+ RHAFDLW KS IP+ +  +
Sbjct: 75  ATQGLNLPTRLLVEPQIFAINTIDYGYPHASYIQKGYINMERHAFDLWQKSRIPSHISTF 134

Query: 119 HDSLCRKIWREDDKWHVIF--RADGWEQHI------TARYLVGADGANSMVRRHLYPDHQ 170
           H +  + + + ++  + +   R D     I       A+ ++GADGA S +RR+LYP  +
Sbjct: 135 HKAYFKSLKQGENGIYTLHFKRQDSKNAKISQDFTCKAKIIIGADGAKSHLRRYLYPQLK 194

Query: 171 IRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTL 230
            +  V IQ+W+  +H  P  SC+FD  +T  YSWS+SK+GYFIFGGAYP  + Q RF T 
Sbjct: 195 TKSLVCIQEWYK-EHNAPMLSCVFDKELTPSYSWSMSKNGYFIFGGAYPHANCQERFATQ 253

Query: 231 KEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYAL 290
            E++    F FGK +K E C VL P+R +DFV G    FLIGEAAGFI+AS+LEGIS A+
Sbjct: 254 IERLRTLGFIFGKPLKKEACLVLQPTRLKDFVLGHSGVFLIGEAAGFINASTLEGISGAM 313

Query: 291 DSTDILRSVLLKQP------EKLNTAYWRATRKLRLK-LFGKIVKSRCLTAPALRKWIMR 343
           +S+ IL  +L            L+ AY    R L +K LF   V+   +  P +R+ I+R
Sbjct: 314 NSSRILAHILNACDMNVSRTSTLHRAYRAKARMLIVKTLFRHYVRYPFMFVPCIRRLILR 373

Query: 344 SGVAHI 349
            G+  +
Sbjct: 374 FGLLRL 379


>UniRef50_Q7VFG9 Putative uncharacterized protein n=1 Tax=Helicobacter hepaticus
           RepID=Q7VFG9_HELHP
          Length = 384

 Score =  258 bits (660), Expect = 2e-67,   Method: Composition-based stats.
 Identities = 160/370 (43%), Positives = 219/370 (59%), Gaps = 23/370 (6%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKMQVIALDKKH---QCGTEGFSKPCGGLLAPDAQRSF 58
             +D+AIIGLG AGS LA  L   ++VIA+DKK     C  E F KPCGGLL+  AQ++F
Sbjct: 6   GEYDIAIIGLGVAGSNLAALLNLHLKVIAVDKKDIQGHCNDEHFHKPCGGLLSQGAQKAF 65

Query: 59  IRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVY 118
              GL LP  ++ANPQIF++ T+D         Q++YIN+ RH FDLW+KSLIP  +  +
Sbjct: 66  AMQGLNLPNTLLANPQIFAINTIDWHYPYASYIQKAYINMERHRFDLWLKSLIPPHIHTF 125

Query: 119 HDSLCRKIWREDDKWHVIFRADGWEQHIT----ARYLVGADGANSMVRRHLYPDHQIRKY 174
           H +  ++I ++   + + F  +   QHI+    AR ++GADGA S +RR LYP  +I   
Sbjct: 126 HKAYFKRIEQKQGFYTIYFTQEQDSQHISYHCNARLVIGADGAKSHIRRWLYPQLKIPSL 185

Query: 175 VAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKM 234
           V IQ+WF E       SCIFD  ++  YSWS+SKD YFIFGGAYP K  +  F T KE++
Sbjct: 186 VCIQEWFKEST-NSMLSCIFDKELSPSYSWSMSKDEYFIFGGAYPHKQCKRAFATQKERL 244

Query: 235 SAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTD 294
               F FG+  K E C VL P+RW+DFV G    FL+GEAAGFI+AS+LEGIS A++S+ 
Sbjct: 245 KNLGFIFGQPFKREACLVLTPTRWRDFVQGHSGVFLVGEAAGFINASTLEGISGAMNSSR 304

Query: 295 ILRS--------VLLKQPE------KLNTAYWRATRKLRLK-LFGKIVKSRCLTAPALRK 339
           IL           L +  +       L+  Y + TR L  K L    V+   +  P  R+
Sbjct: 305 ILSEILNNEEFNALSRNKDIALWYKLLHRTYTKRTRFLVCKTLLRHYVRYPFMFIPLFRR 364

Query: 340 WIMRSGVAHI 349
           +I+R G+  +
Sbjct: 365 FILRFGILRV 374


>UniRef50_C6JQS4 FAD dependent oxidoreductase n=1 Tax=Fusobacterium varium ATCC
           27725 RepID=C6JQS4_FUSVA
          Length = 355

 Score =  253 bits (646), Expect = 9e-66,   Method: Composition-based stats.
 Identities = 112/349 (32%), Positives = 187/349 (53%), Gaps = 6/349 (1%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEG-FSKPCGGLLAPDAQRSFIRDG 62
           +D+ +IG GPAGS  ++ +  K +V+ LD++          K CGGLLA +AQ +    G
Sbjct: 3   YDIVVIGGGPAGSVFSKFINSKYKVLLLDRRDYEDENNKIIKCCGGLLAHEAQAALSGLG 62

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSL 122
            +L  D++ +PQ+F+V+ +D   +L + Y ++Y+N +R  FD ++ S   + VE+   +L
Sbjct: 63  YSLSKDILVSPQVFNVQVIDYDNNLKKKYYKNYLNFDREKFDNYLLSQKASHVELIKGAL 122

Query: 123 CRKIWREDDK-WHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWF 181
                 +++  + VI+R     + +  + +V A+GANS++R++L  +     Y+AIQ+ +
Sbjct: 123 FIDYSEDENGIYTVIYRIGMDIKKVKTKMIVSAEGANSLIRKNLD-NKSKNDYIAIQRVY 181

Query: 182 AEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQ-TRFTTLKEKMSAFQFQ 240
             K    ++  IFD +I N YSW + K    I G       G   +F  L+E++ +    
Sbjct: 182 KMKKDFSYHMAIFDKNINNYYSWLVPKGNELILGTILKKGKGSWDKFHQLEERVKSEGID 241

Query: 241 FGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVL 300
               ++ E   +  P +W ++   KD   LIGEAAG ISASS EGISYAL S   L   +
Sbjct: 242 INDIIRDEGTFIRVP-KWNEYFMAKDRIALIGEAAGLISASSSEGISYALISGYYLADSI 300

Query: 301 L-KQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAH 348
             K  +     Y + T  +R+KL  KI+K + +    +RK+I+ SGV  
Sbjct: 301 NKKGIKSGIIEYCKRTESIRMKLNLKILKGKLMYNSFIRKFIIMSGVFS 349


>UniRef50_D1RCG6 Geranylgeranyl reductase family protein n=1 Tax=Legionella
           longbeachae D-4968 RepID=D1RCG6_LEGLO
          Length = 503

 Score =  246 bits (629), Expect = 9e-64,   Method: Composition-based stats.
 Identities = 80/327 (24%), Positives = 122/327 (37%), Gaps = 23/327 (7%)

Query: 5   DVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL- 63
           DV I G GP+G+  A  LA   + + L   H   +    K CG  ++P + +  +  G+ 
Sbjct: 27  DVLIAGAGPSGAICAYYLAQAGKKVILIDSH---SFPRDKVCGDFVSPVSLKELMTLGIT 83

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQR------SYININRHAFDLWMKSLIPA-SVE 116
            LP     N    +   VD    +T N  +          I R   D W+ +      V 
Sbjct: 84  DLPEFKATNMITEATVYVDGQKLITDNIPQIKDFVNYGRVIPRVLLDTWIVNAAKQQGVN 143

Query: 117 VYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKY-- 174
           V  D      +  +    V     G ++    + LVGADG+NS V R L       K+  
Sbjct: 144 VITDCKLVNYFVNEQDVRVECEQHGKKRRFLIKILVGADGSNSTVARILQGKKPNPKHKI 203

Query: 175 VAIQQWFAEKHPVPFYSCIFDNSIT-NCYSWSISKDGY-FIFGGAYPMKDGQTRFTTLKE 232
           VA++ +    + +P  + +F    T   Y W           G    +K      T LK 
Sbjct: 204 VAVRAYCENINCIPHQATLFFTRNTFPGYFWFFPTSSTTANVGIGMVLKTFPKNETNLKA 263

Query: 233 KMSAF--QFQFGKTVKSEKCTVLFPSRWQDFVC------GKDNAFLIGEAAGFISASSLE 284
            +        F KT  S+   +   + W            KD   L G+AAGFI+  + E
Sbjct: 264 MLLEMIGNDPFFKTKISQGMQITKIAGWPLSCYDPSTINVKDRVLLTGDAAGFINPFTGE 323

Query: 285 GISYALDSTDILRSVLLKQPEKLNTAY 311
           GI YAL S  +    ++   E  N + 
Sbjct: 324 GIQYALQSGRLAAETIIGSFETENFSA 350


>UniRef50_Q649G8 Geranylgeranyl reductase n=3 Tax=environmental samples
           RepID=Q649G8_9ARCH
          Length = 385

 Score =  239 bits (610), Expect = 1e-61,   Method: Composition-based stats.
 Identities = 68/349 (19%), Positives = 124/349 (35%), Gaps = 23/349 (6%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           M+ +DV +IG GP+G+  ++  AG      L +K         K CGG ++  A      
Sbjct: 1   MQQYDVIVIGAGPSGAIASKTCAGNGLKTLLFEKEGI---PRLKLCGGAVSTSALSDLD- 56

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMK-SLIPASVEVYH 119
               +  D+I      +           +   R  I ++R  FD ++    + A V ++ 
Sbjct: 57  --FGIEKDLIERECYGARVHFKTHQIEVKRKSRLAILVSRDKFDAYLVSKAVDAGVALHE 114

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPD-HQIRKYVAIQ 178
                 I  E  +  V       ++   A+ ++GADG NS+V +++            I 
Sbjct: 115 AEKATSIKPEQSRIVVET----NKEKYNAKVVIGADGVNSIVSKYVRDSYKPDELGFCIA 170

Query: 179 QWFAEKHPV-----PFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEK 233
                 +            I        Y W   K+ +F  G    +          ++ 
Sbjct: 171 AEIPASNEEVNEYIENAIDIHYGITNFGYGWVFPKEKHFSVGLCGILPS----MKNSRDI 226

Query: 234 MSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDST 293
             AF  + G +        L P+   +     D   L+G+AAGF+     EGI YA  S 
Sbjct: 227 FIAFIKKLGFSTDVNSHAHLIPAGGYEREVCSDRIMLVGDAAGFVDPYQGEGIKYAFISA 286

Query: 294 DILRSVLLKQPEK--LNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKW 340
            +    +++  E    + +     ++    LFG+ +K        + K+
Sbjct: 287 KLAAERVVESYENDEFSKSALDTYKRTCYSLFGENLKYSLRLTRLMYKY 335


>UniRef50_B5W6L5 Geranylgeranyl reductase n=2 Tax=Arthrospira RepID=B5W6L5_SPIMA
          Length = 378

 Score =  235 bits (601), Expect = 1e-60,   Method: Composition-based stats.
 Identities = 72/339 (21%), Positives = 111/339 (32%), Gaps = 18/339 (5%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           FD  I+G GPAG+  A  LA K   I +  K         KPCGG ++P  Q  F  D  
Sbjct: 3   FDCIIVGSGPAGATAAYHLAKKGHSILVIDKAIL---PRYKPCGGGVSPIVQDWFDFDFS 59

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLW-MKSLIPASVEVYHDSL 122
                          K+  +   L  N       + R  FD + +K  I     V  ++ 
Sbjct: 60  PAISLKTVMVYYTWNKSEPIEVELKIN---PIWMVRREVFDYFILKQAISKGATVRDNTE 116

Query: 123 CRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYV-AIQQWF 181
              I  + D+W V       E   T RYL+GADGA   + + L    Q +    A++   
Sbjct: 117 VLGIEFQSDRWLVKT----PEDTYTGRYLIGADGAKGPLAKWLGFTKQKKLVAGALELEI 172

Query: 182 AEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQF 241
               PV   +      + + Y W+  K   +  G     K  +      K  +  +   F
Sbjct: 173 PTSKPVDMKTYFEFGLVNSGYGWNFPKADGYSLGAGAFSKQRKA--QNFKRILEDYATFF 230

Query: 242 GKTVKSE-KCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVL 300
              + +  +C                NA L GEAA  +   + EGI  ++ S       +
Sbjct: 231 NLNLDNATECGHPISLWDGQQKLHTQNAVLAGEAACVVDPFTAEGIRPSIFSGLKAAEAI 290

Query: 301 LKQPEK---LNTAYWRATRKLRLKLFGKIVKSRCLTAPA 336
            +           Y     +          K   +    
Sbjct: 291 NQALGGDINALDKYTEVMNEEWGNQMMFAQKLAQIFYRF 329


>UniRef50_Q1IMS5 Geranylgeranyl reductase n=1 Tax=Candidatus Koribacter versatilis
           Ellin345 RepID=Q1IMS5_ACIBL
          Length = 379

 Score =  230 bits (586), Expect = 8e-59,   Method: Composition-based stats.
 Identities = 78/356 (21%), Positives = 126/356 (35%), Gaps = 25/356 (7%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           M H    I+G GP+G+A A  LA     + L  + +       KPCGG L     ++   
Sbjct: 1   MGHQSFIIVGAGPSGTAAAYDLAKAGHSVLLLDRSE---FPRVKPCGGGLTVKTLKALRY 57

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLW-MKSLIPASVEVYH 119
                PV  I    +     +     L   +   ++ + R  FD + ++  + A      
Sbjct: 58  S--VTPVVRIVAKGLQVTNNLAEPIELRGKHPICFMTV-RAEFDDFCLRQTLEAGARFQK 114

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQ 179
            S    +    D   +  R    +    A YL+GADGANS VR  L      R+ +A++ 
Sbjct: 115 ISEITGVEEFPDHVVLRTR----DGEFHAEYLLGADGANSKVRLLLGAQPWFRRAIAVEA 170

Query: 180 WFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQF 239
                         F   +   Y+WS  K  +   G      +       L       + 
Sbjct: 171 HAPVHKNAKAMEIDF-GVVPRGYAWSFHKGDHLNVGLCTESAEVVKLSRDLLANY--LKR 227

Query: 240 QFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSV 299
           +FG    S             +       FL+G+AAG     S EGI  A+ S     S 
Sbjct: 228 KFGSDEYSHFVGHYLGIGGMRYEPKHKRIFLVGDAAGMTDPLSGEGIYNAIKSGQAAASA 287

Query: 300 LLKQPEKLNTAYWRATRKLR----------LKLFGKIVKSRCLTA-PALRKWIMRS 344
           LL+  E  + +Y +A   +R           K +G +     +   P ++K I++ 
Sbjct: 288 LLQNSEAPHVSYAQALADVRDDLEFCERAIGKFYGHLNAGFAMLKVPGMKKSILKG 343


>UniRef50_O29786 Digeranylgeranylglycerophospholipid reductase n=1 Tax=Archaeoglobus
           fulgidus RepID=GGR_ARCFU
          Length = 387

 Score =  230 bits (586), Expect = 8e-59,   Method: Composition-based stats.
 Identities = 65/344 (18%), Positives = 112/344 (32%), Gaps = 19/344 (5%)

Query: 4   FDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +DV ++G GPAGS  A+  A   ++V+ ++K+ + GT      C   ++ ++   F    
Sbjct: 2   YDVVVVGAGPAGSMAAKTAAEQGLKVLLVEKRQEIGTPVR---CAEGISRESIEKFFEVD 58

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKS-LIPASVEVYHDS 121
                  +   +I++    ++  S           + R  FD  +      A  EVY  +
Sbjct: 59  KKWIAAEVTGAKIYAPNKTEIVMSEEMAGNEVGYVLERKIFDRHVARLAAKAGAEVYVKT 118

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKY---VAIQ 178
                 R+D K  V  R  G +  +  + L+GADG  S + R       ++        Q
Sbjct: 119 AMVDFERKDGKVKVKLRRLGEDWEVETKILIGADGVESKIGRKAGIIKTLKLNEVESCAQ 178

Query: 179 QWFAEKHPVPFYSCIFDNS--ITNCYSWSISKD-GYFIFGGAYPMKDGQTRFTTLKEKMS 235
                      Y+  +         Y+W   K  G    G     K  +       +   
Sbjct: 179 YLMTGLDIDESYTYFYLGRELAPGGYAWIFPKGNGSANVGIGVLPKMAERTAKEYLDAFI 238

Query: 236 AFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDI 295
             +   GK V  E      P   +      DN  L G+AA      +  GI+ AL +   
Sbjct: 239 EKEGIEGKIV--EFVAGAVPVYGEIETAVADNIMLAGDAAYHADPITGGGIANALSAGYY 296

Query: 296 LRSVLLKQ------PEKLNTAYWRATRKLRLKLFGKIVKSRCLT 333
              V  +              Y    +    K   +  K +   
Sbjct: 297 AGKVAAEAVQKNDFSADFLRRYDELWKNDFGKKLRRNKKLQLKF 340


>UniRef50_Q648X7 Geranylgeranyl reductase n=4 Tax=environmental samples
           RepID=Q648X7_9ARCH
          Length = 420

 Score =  229 bits (585), Expect = 1e-58,   Method: Composition-based stats.
 Identities = 62/349 (17%), Positives = 120/349 (34%), Gaps = 24/349 (6%)

Query: 2   EHFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           E +DV ++G GPAGS  A+  A   + V+ +++  + G       CG  ++ + +R    
Sbjct: 28  EKYDVVVVGAGPAGSITAKTAAERGLDVLLIERNPEIG---VPVKCGECVSKEIER---- 80

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRS---YININRHAFDLWMK-SLIPASVE 116
             + +    +      ++        +  + + +      + R  FD  +      A  E
Sbjct: 81  -FVDIDRRWVCAGIRGTITYGPDGTKVILSVEGAEEVGYVLERKIFDKCLAQEAARAGAE 139

Query: 117 VYHDSLCRKIWREDD---KWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRK 173
           V   +    +  +       +        +  I+A  +VGADG  S V +    D  +  
Sbjct: 140 VRVKTQVYGVVNDGGYAKGVYARTAEAEGDIRISADVVVGADGVESRVGKWGGIDTTLHL 199

Query: 174 Y----VAIQQWFAEKHPVPFYSCIF-DNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFT 228
                 A       +    +    F D+     Y W   K  +    G     D      
Sbjct: 200 ADVATCAQFLMCDIEVNNEYCEIFFGDDVAPKGYGWIFPKGDHCANVGLGIGGDVSNENH 259

Query: 229 TLKEKMSAF-QFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGIS 287
             ++ ++AF   +F       +     P     +    +   L+G+AA  ++  +  GI 
Sbjct: 260 CARDYLNAFVGGKFPNGKIIAEMYGAVPLSGPVYETVANGLILVGDAARHVNPITGGGIL 319

Query: 288 YALDSTDILRSVLLKQ--PEKLNTAYWRATRKLRLKLFGKIVKSRCLTA 334
            A+   +I   V+ K       +    R   K   K FGK++K+   T 
Sbjct: 320 EAMQGGEIAGDVIAKAVQENDFSKRRLREYEKRWRKEFGKVLKAGLKTK 368


>UniRef50_Q11W52 Probable electron transfer flavoprotein n=1 Tax=Cytophaga
           hutchinsonii ATCC 33406 RepID=Q11W52_CYTH3
          Length = 384

 Score =  228 bits (581), Expect = 3e-58,   Method: Composition-based stats.
 Identities = 69/358 (19%), Positives = 127/358 (35%), Gaps = 27/358 (7%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
            FDV I+G GPAGS  A  L      +AL +K         K CG  L+  A+R   +  
Sbjct: 8   SFDVIILGAGPAGSTAALALQKSNLTVALLEKEL---FPRDKICGDALSCVAERVLKQID 64

Query: 63  LTLPVDVIANPQIFSVK----TVDVAASLTRNYQRSYININRHAFDLWMKSLIPA-SVEV 117
            +L  +++   +   V           S+  N+ +    I R  FD W+     A ++EV
Sbjct: 65  PSLEQELLLYSEKTVVNKARVYSPEFRSIVLNFSKRGHCIKRLDFDNWLFEKANAKNIEV 124

Query: 118 YHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYV-- 175
           +  +    +  ++    V+ +       + A  ++  DGA+S+  R L      RK+   
Sbjct: 125 FQQAKVTDVRIDNSGAEVVLQ---DGTILHAAIVICCDGAHSVAARQLTHLKLDRKHYVG 181

Query: 176 AIQQWFAEKHPVPF--YSCIFDNSITNCYSWSIS-KDGYFIFGGAYPMK-------DGQT 225
           A++Q++              F       Y W    K+G    G             D + 
Sbjct: 182 AVRQYYRNISDTAGNELEIFFLKDFLPGYFWIFPLKNGEANVGFGALSAIISKNKIDLKK 241

Query: 226 RFTTLKEKMSAFQFQFGKTVKSEKCTVL-FPSRWQDFVCGKDNAFLIGEAAGFISASSLE 284
               + + +   + +F      E       P   +       +  L G+AA  I   + E
Sbjct: 242 SLQEIIQSVPQLKERFKDAEAMETVKGFGLPLGSRKLPISGAHFMLCGDAASLIDPVTGE 301

Query: 285 GISYALDSTDILRSVLLKQPEKLNTAYW---RATRKLRLKLFGKIVKSRCLTAPALRK 339
           GI  A++S        ++  E  + +        +++  K+F +  +   L      +
Sbjct: 302 GIETAMESGKYAAEQAIRCFESTDFSAACMQAYDQRIHKKMFKRFRQHYVLQRLISDR 359


>UniRef50_A5D4V1 Dehydrogenases n=1 Tax=Pelotomaculum thermopropionicum SI
           RepID=A5D4V1_PELTS
          Length = 386

 Score =  224 bits (572), Expect = 4e-57,   Method: Composition-based stats.
 Identities = 73/345 (21%), Positives = 114/345 (33%), Gaps = 22/345 (6%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
            +DV I G GPAGS LAR+LAG    + + +K         KPCGG +   A R      
Sbjct: 2   KYDVVIAGAGPAGSTLARRLAGAGLEVLVLEKEFM---PREKPCGGGITYKAARLLDF-- 56

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRS-YININRHAFDLWMKSLIP-ASVEVYHD 120
                DVI +    +V +    + +T   +      + R +FD  +      A   +   
Sbjct: 57  --PWQDVIEDTVHTAVFSYQGKSEVTVRLKTPLAYMVTRSSFDRMLADRARQAGACLVEG 114

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW 180
           +  + I  E+    V        +    R  VGADG N      L   H       ++  
Sbjct: 115 APVKDIAVENGLVTVAAA----GETYHGRLFVGADGVNGRSAMLLGLHHPGETGPTLEAE 170

Query: 181 FAEKHPV----PFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSA 236
            A    V         +   ++   Y W   K      G     +  +     L   ++ 
Sbjct: 171 VACPPEVLEQKRGTIRLDCGAVPWGYGWVFPKRDRLSTGVGAFTRKVKELKKLLGGFLA- 229

Query: 237 FQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDIL 296
            +   G            PS  +       +A LIG+AAG +   S EGI YA+ S  + 
Sbjct: 230 -REGLGSARILSLRGYPIPSGGRKKRIHSRSALLIGDAAGLVDPFSGEGIYYAIKSAHLA 288

Query: 297 RSVLLKQ---PEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALR 338
              +L     PE     Y     +       +  +   +     R
Sbjct: 289 AEAILDSRAQPEGAPGLYQSLVDRHVTAELMEARRLARVFYTFPR 333


>UniRef50_A6QA88 Geranylgeranyl hydrogenase n=1 Tax=Sulfurovum sp. NBC37-1
           RepID=A6QA88_SULNB
          Length = 361

 Score =  223 bits (570), Expect = 6e-57,   Method: Composition-based stats.
 Identities = 83/336 (24%), Positives = 139/336 (41%), Gaps = 28/336 (8%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           M   D+ IIG GPAGS LAR LA   +   L ++       F KPCGG +  DA   F  
Sbjct: 1   MIRTDILIIGGGPAGSTLARYLAEAGKETILVQR----NFNFRKPCGGGIRLDAFDEFDI 56

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD 120
           D   +  +V +   +F  K V+V  S     Q     ++R  FD ++++    +     +
Sbjct: 57  DRELIRKEVNSIALVFGTKRVEVDIS-----QMPLGIVDRVEFDTYLRNRAEDTGATLLE 111

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW 180
           +    +   D    V    DG  + I A YLVGADG NS VR+ +  D       +    
Sbjct: 112 ASFVDVEVCDGYIIVTIEQDGVYKKIHAGYLVGADGVNSKVRKCINGDR----VPSAMTR 167

Query: 181 FAEKHPVPFYSCIFD---NSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAF 237
           +A+     + +C F        + Y+W+         G      D +T      +++   
Sbjct: 168 YADLAHTAYKTCEFHFGSKVAGSYYAWAFPHTNGSNIGTLA--GDDETHIQHFMKQL--- 222

Query: 238 QFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILR 297
                   +  K       ++++ V  KD  F +G++A  +   + EGI YA+ S  +L 
Sbjct: 223 -----DVKEKVKLLGYRIPQFENPVFYKDRVFFVGDSASQVLPFTYEGIYYAMASAHLLS 277

Query: 298 SVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLT 333
           +VL +Q +   + Y +      L+ F  + + + L 
Sbjct: 278 AVLTEQADP--SEYEKRWNDTYLQKFTTLQRLQKLF 311


>UniRef50_Q2NFZ1 Digeranylgeranylglycerophospholipid reductase 1 n=4
           Tax=Methanobacteriaceae RepID=GGR1_METST
          Length = 403

 Score =  222 bits (566), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 61/352 (17%), Positives = 113/352 (32%), Gaps = 20/352 (5%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M   DV +IG GPAGS  A+  A     V+ +DKK + GT    K C   +  +  +   
Sbjct: 1   MLKTDVVVIGAGPAGSMAAKHAALGGANVVLIDKKSEIGT---PKRCAEGVYDEGFKWLN 57

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLT---RNYQRSYININRHAFDLWMK-SLIPASV 115
              +      IA     +        S T    +       + R  FD  M      A  
Sbjct: 58  ---IEPDERWIAQRIYGATLHSPDGNSFTVTSEDVPVQGFILERKVFDKHMAMDAARAGA 114

Query: 116 EVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYV 175
           ++   +L   I R ++ + +   +      + A+  + ADG  S++ + L  +    + +
Sbjct: 115 KIMIKTLVTDIKRNENGFILSCDSIEGTIEVEAKIAICADGPESIMAKKLGINSTTPQNM 174

Query: 176 ---AIQQWFAEKHPVPFYSCIFDN--SITNCYSWSISKDGYF-IFGGAYPMKDGQTRFTT 229
              A  +     +        +         Y+W   K       G        +T +  
Sbjct: 175 MSCAQFEMCNVDYNDDEKIEFYLGQDVALKGYAWIFPKGNGVANVGLGVTGNTDKTAYEY 234

Query: 230 LKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYA 289
           + + +             E      P          DN  + G+AAG ++     GI   
Sbjct: 235 IMDFIEKC-PATKNAQPIEMNIGGDPINGLIEKIYDDNLLICGDAAGQVNPIEGGGIIEG 293

Query: 290 LDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWI 341
           +        V  K  ++    Y +       + + ++  +   T PA R  +
Sbjct: 294 MLGGMAAGDVAAKAIKE--ENYSKERLHEYYEKYSELSFNLIETLPAARDIV 343


>UniRef50_Q2RKB3 Geranylgeranyl reductase n=1 Tax=Moorella thermoacetica ATCC 39073
           RepID=Q2RKB3_MOOTA
          Length = 378

 Score =  221 bits (565), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 71/349 (20%), Positives = 109/349 (31%), Gaps = 20/349 (5%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
            +DV I G GPAGS   R LA +   +A+  +         KPCGG L   AQ       
Sbjct: 2   QYDVLICGAGPAGSTCGRLLARQGLKVAIFDRA---RFPRYKPCGGGLTGKAQGELEAGW 58

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMK-SLIPASVEVYHDS 121
             L  D       +  +   +  +     Q     ++R  FD W+      A  EV    
Sbjct: 59  EDLIEDTTREVIFYHRQERPLKITCE---QPVIKMVSREKFDSWLLTEAARAGAEVRDGY 115

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWF 181
               +        V             R+LVGADGA S+VRR L         + ++   
Sbjct: 116 RVTGVTETAGGVKV---QGQDGCTWEGRFLVGADGALSLVRRSLPFKPGGTAGITLECEV 172

Query: 182 AEKHPV----PFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAF 237
                +         +    I   Y W   K  +   G     +  +             
Sbjct: 173 PVDAGLLTSYRGQVHLSYGGIPYGYGWVFPKGDHLSVGIGSFTRRVKGLRRYFDTFCRGL 232

Query: 238 QFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILR 297
                  ++     +         V     A L+G+AAG +   S EGI YAL S  +  
Sbjct: 233 GLAVPANLRCRGAVIPAADGQAG-VFHTGRALLVGDAAGLVDPFSGEGIYYALRSGRLAA 291

Query: 298 SVLLK--QPEKLNTAYWRATRKLRLK---LFGKIVKSRCLTAPALRKWI 341
             ++          AY R      L+      +I +      P + + +
Sbjct: 292 ETIMATLAGTGEPGAYSRRLYDELLQPLHYARRIARVVYALTPVVHRLV 340


>UniRef50_B3ECC8 Geranylgeranyl reductase n=3 Tax=Chlorobium RepID=B3ECC8_CHLL2
          Length = 389

 Score =  221 bits (563), Expect = 4e-56,   Method: Composition-based stats.
 Identities = 64/345 (18%), Positives = 110/345 (31%), Gaps = 19/345 (5%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
             +   ++G GP+GS+ A   A   M V  +DK          K CGGLL    ++ F+ 
Sbjct: 3   NFYTCLVVGAGPSGSSAAYTFAKNGMDVCVIDK----AIFPRDKLCGGLLTRRTKQCFLD 58

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLI-PASVEVYH 119
              T   D+       ++                    NR  FD  +   +     +V  
Sbjct: 59  VFGTGWEDIHECWSNGALFFHKGQMINAIENYGELFFCNRRTFDHALLEKVMAKGADVVL 118

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPD--HQIRKYVAI 177
                 +        +        + I  RYL+GADG NS+V R +      + R   A+
Sbjct: 119 GDRVEGVD-----TTLKMCRLRSGREIRYRYLIGADGVNSVVARAVTSKGFDRNRYAFAV 173

Query: 178 QQWFAE---KHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKM 234
           Q    +   +        I+   +   Y W   K   +  G     +         +E  
Sbjct: 174 QAETPDVICRQNDMILPEIYFGEVDWGYGWVFPKKNSYSVGIGALCQKNGDVAGKFREFY 233

Query: 235 SAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTD 294
            A   Q              P           +  ++G+AAG +   + EGI+YA++S  
Sbjct: 234 LARNSQPCSVTLKG---HYIPFGNFSRNAVAKDIVIVGDAAGLVDPITGEGIAYAIESGQ 290

Query: 295 ILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRK 339
                ++      N        K   K+  +I ++  L      +
Sbjct: 291 YAAQAVILASSNKNITLADEYEKYYSKITQEIDRANMLQYYLFSR 335


>UniRef50_B8HM17 Geranylgeranyl reductase n=1 Tax=Cyanothece sp. PCC 7425
           RepID=B8HM17_CYAP4
          Length = 376

 Score =  220 bits (561), Expect = 7e-56,   Method: Composition-based stats.
 Identities = 65/351 (18%), Positives = 118/351 (33%), Gaps = 20/351 (5%)

Query: 3   HFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            +D+ I+G GPAG+ LA       ++ + LDK          K CG  +     +     
Sbjct: 4   EYDLIIVGGGPAGTTLALFAHRAGLKTLLLDK----ARFPRDKICGDAIILPGIKILEEL 59

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSY-ININRHAFDLWMKSLIPASVEVYHD 120
            LT  +     P  +SV       S       S+ + + R  FD  + +   A V+    
Sbjct: 60  ELTAAL--HQGPHSYSVNFHCFTESEHLQAPGSHCLMVKRLYFDHVLFTAAKAVVDTCEG 117

Query: 121 SLCRKIWREDDKW-HVIFR-ADGWEQHITARYLVGADGANSMVRRHLYPDH--QIRKYVA 176
           +   ++ +++ +   V  R  +  E   TA+ +VGADG  S+V +             VA
Sbjct: 118 AEVEQLLQQEGQVYGVRGRLQNQEEFEFTAKVVVGADGCGSVVAKKAGVFKFEPQHYGVA 177

Query: 177 IQQWFAEKHPV--PFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKM 234
            + ++              +       Y W    D   +  G             L +++
Sbjct: 178 TRAYYRHLPLPYGKAIEFYYFQECLPGYLWIFPVDQETVNVGVGVEPSPNQALPKLHQQL 237

Query: 235 SA---FQFQFGKTVKSEKCTVL-FPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYAL 290
                 + +F +     +      P   +      +   LIG+AAG I     +GI  A+
Sbjct: 238 LESPLLKSRFAEAELIGQIQAWSLPLASKQRKIHGNGFILIGDAAGLIDPFWGDGIDKAM 297

Query: 291 DSTDILRSVLLK--QPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRK 339
            S  +   VL +  + +  + A  +          G   +  C       K
Sbjct: 298 LSAKVAAQVLAEVCRGQDYSAAALQDYPDSLWSQLGAKFQYSCRLRQRFHK 348


>UniRef50_A6UWL1 Digeranylgeranylglycerophospholipid reductase n=12
           Tax=Methanococcales RepID=GGR_META3
          Length = 391

 Score =  219 bits (559), Expect = 1e-55,   Method: Composition-based stats.
 Identities = 60/350 (17%), Positives = 104/350 (29%), Gaps = 25/350 (7%)

Query: 3   HFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            +DV +IG GP GS  +   +    + + +DK  + GT      C       A       
Sbjct: 8   EYDVIVIGAGPGGSMASYHSSINGAKTLLIDKSQEIGTPVR---CAE-----AVPYLDEF 59

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQR-SYININRHAFDLWMKSL-IPASVEVYH 119
           G+      I +     +        +     +     + R  FD  +         ++  
Sbjct: 60  GINPDPSFIRSKIDGGILVAPNGKKIIVKGGKTQGYVVERKIFDKHLAVRSANVGTKIAI 119

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRK----YV 175
            S    +  + +K+ VI    G    I A+ ++ ADG  S +        + +       
Sbjct: 120 KSRVVGLDYDGEKYTVIVNHLGQIYAIKAKIVIAADGVESSIAEMAGIKCKKKVTEICSC 179

Query: 176 AIQQWFAEKHPVPFYSCIFDNSI-TNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKM 234
           A  +    K         +   I    Y W   K      G    +   +     L E +
Sbjct: 180 AEYEMTNVKLLDKNMMEFYFGDICPKGYVWIFPKGETANVGLGI-IDSKKKAIDYLNEFL 238

Query: 235 SA--FQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDS 292
                + +       E      P          DN  ++G+AAG IS  S  GI  +L  
Sbjct: 239 EHPLLEGRLDNATPIEFKCGGAPVGGPIEKTVADNFMVVGDAAGQISPISGGGIYLSLSC 298

Query: 293 TDILRSVLLKQ------PEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPA 336
             I   V  +        E     Y    ++   KL    +K + +    
Sbjct: 299 GSIAGKVAGEAIKSNNCSEDYLVEYENRWKEKYYKLLMDELKYKKVLQKF 348


>UniRef50_Q12YW2 Digeranylgeranylglycerophospholipid reductase 1 n=8
           Tax=Euryarchaeota RepID=GGR1_METBU
          Length = 408

 Score =  218 bits (556), Expect = 2e-55,   Method: Composition-based stats.
 Identities = 60/345 (17%), Positives = 109/345 (31%), Gaps = 24/345 (6%)

Query: 1   MEH-FDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSF 58
           M+  +D+ ++G GPAGS  A   A   + V+ L+K+ + G       C   +     R  
Sbjct: 1   MKDQYDLVVVGAGPAGSIAATTAAKKGLSVLMLEKRQEIGEPVR---CAEGVGKKRLRQH 57

Query: 59  IRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLI-PASVEV 117
           I          +++ +I S     +  +           ++R  FD  +  L   A V++
Sbjct: 58  IELDEKWLCGEVSSAKIISPNGTTLTMAEEDAGSEVGYVLDRKIFDRTLVELSGEAGVDI 117

Query: 118 YHDSLCRKIWREDDKW-HVIFRADGWEQHITARYLVGADGANSMVRRHLYPD---HQIRK 173
              +    +  E++    V     G    I ++ ++GADG  S V R    D        
Sbjct: 118 MVKARVTGLIIEENTVCGVEMMHLGKTYSIRSKLVIGADGVESKVGRWAGIDTSLKPSHI 177

Query: 174 YVAIQQWFAEKHPVPFYSCIFDNS--ITNCYSWSISKDGY-FIFGGAYP--MKDGQTRFT 228
               Q   +           +  +      Y W   K       G          +    
Sbjct: 178 ETCAQFLVSGVDIDQSSCYFYMGNKVAPGGYVWVFPKGNNMANVGIGILGSRAGEKKPIE 237

Query: 229 TLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISY 288
            L + + A    +      E+     P+         +   L+G+AA      +  GIS 
Sbjct: 238 YLTDFVEAN---YPNGSIIEQVAGAVPASGPIEKTIANGLMLVGDAARQSDPFTGGGISN 294

Query: 289 ALDSTDILRSVLLKQ------PEKLNTAYWRATRKLRLKLFGKIV 327
           A+D+      V  +        EK+   Y +  R          +
Sbjct: 295 AMDAGLYAGEVAAEAIAQDDVSEKILQKYEKRWRGSFGNEIANNL 339


>UniRef50_C6BUN1 Geranylgeranyl reductase n=1 Tax=Desulfovibrio salexigens DSM 2638
           RepID=C6BUN1_DESAD
          Length = 380

 Score =  217 bits (553), Expect = 6e-55,   Method: Composition-based stats.
 Identities = 65/370 (17%), Positives = 116/370 (31%), Gaps = 31/370 (8%)

Query: 2   EHFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
             FDV I G GP GS  A  LA    +V  +DK          K CGGLL   A     +
Sbjct: 3   GKFDVIIAGAGPTGSTAATILAGKGFKVALIDKAE----FPRKKLCGGLLTYKATEVLNK 58

Query: 61  DGLTLPVDVIANPQI------FSVKTVDVAASLTRNYQRSYININRHAFDLWMKS-LIPA 113
                   +     I      +S+   D            +  ++R  FD ++      A
Sbjct: 59  IFGCDVDCLKKQGIINFESPEYSINYRDY-NIRDAESSIPFRFVDRIDFDYFLLQKAANA 117

Query: 114 SVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQI-- 171
             +++     ++   +D +           +    +YL+GADG +S +RR +  D +   
Sbjct: 118 GAQIFTGEEIKECNYQDAEI-----KTASNRIFKGKYLIGADGVHSTIRRSVPYDKKKWR 172

Query: 172 RKYVAIQQWFAEKHPVPFYS---CIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFT 228
               A  +   +K   P       ++   +   Y W     G  + G     +       
Sbjct: 173 DDMAATIEIIFDKKDFPREVAKPELYIGHLRAGYIWVFPAKGKVVTGIGALTRCTTDFKK 232

Query: 229 TLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISY 288
           T  + + +                  P              L G+AAG +     EGI Y
Sbjct: 233 TYMDFLRSQG--IANPESMHMQGYPLPYGNFMENPCFGRTLLAGDAAGLVEPLFGEGIFY 290

Query: 289 ALDSTDILRSVLLKQP---EKLNTAYWRATRKLRLKLFG---KIVKSRCLTAPALRKWIM 342
           AL +       + +     +  +  Y     K          ++  +   + P L+    
Sbjct: 291 ALQTGRYAAESIARGITENKSPDKFYLERLEKYVFPELRYSNRLRWTLFYSQPLLKHMSF 350

Query: 343 RSGVAHIPQL 352
           +     +P++
Sbjct: 351 KMMFKSMPRI 360


>UniRef50_Q2NER9 Digeranylgeranylglycerophospholipid reductase 3 n=2
           Tax=Methanosphaera stadtmanae DSM 3091 RepID=GGR3_METST
          Length = 397

 Score =  216 bits (552), Expect = 8e-55,   Method: Composition-based stats.
 Identities = 77/350 (22%), Positives = 112/350 (32%), Gaps = 26/350 (7%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           ++  DV IIG GPAGS  AR+ +    + + +DKK + GT    K C   +         
Sbjct: 3   IKEVDVLIIGAGPAGSLAAREASKNGAKTLIIDKKSEIGT---PKRCAEGIMSG---VLE 56

Query: 60  RDGLTLPVDVIANPQIFSV-----KTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPA 113
           R  +T     IA     +       T       T     + I + R  FD  M    I  
Sbjct: 57  RVHITPDERWIARKIDGARIVSPNNTSAWFTPETLETPATGIILERKVFDKHMTMDAIRE 116

Query: 114 SVEVYHDSLCRKIWREDDKWHVIFRADGWEQ-HITARYLVGADGANSMVRRHLYPDHQIR 172
             EV   +    + RE D + V  ++   E   I A  ++GADG    V R    + ++ 
Sbjct: 117 GAEVMIKTEALSMKREGDGYLVDIKSFNKEYNQIKAHIVIGADGPEGHVARWAELNTKVP 176

Query: 173 KY---VAIQQWFAEKH--PVPFYSCIFDNSITNCYSWSISKD-GYFIFGGAYPMKDGQTR 226
                  +Q                 F +     Y+W   K       G        +  
Sbjct: 177 LAEMESGLQYEMTNLKMKNNSVIQFFFGSVAPGGYAWIFPKGYDTANVGIDISGIKAEKS 236

Query: 227 FTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGI 286
                    A   +       E      P          DN  L+G+AAG +S  +  GI
Sbjct: 237 AVKYLNDFIANCDETKDGQIVEINAGGNPLCGIFDKIITDNVMLVGDAAGCVSPITGGGI 296

Query: 287 SYALDSTDILRSVLLKQ------PEKLNTAYWRATRKLRLKLFGKIVKSR 330
             AL+S  I   V  K        E+    Y         K F K +  R
Sbjct: 297 DTALESGMIAGRVAAKAIKNRDYSEEKLQEYADYIDSHLGKKFKKYIAIR 346


>UniRef50_C5A6E5 Digeranylgeranylglycerophospholipid reductase n=9
           Tax=Thermococcaceae RepID=GGR_THEGJ
          Length = 395

 Score =  216 bits (552), Expect = 8e-55,   Method: Composition-based stats.
 Identities = 66/343 (19%), Positives = 119/343 (34%), Gaps = 22/343 (6%)

Query: 3   HFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            +DV ++G G AG  +AR +A     V+ +DKK   GT    K C   ++    + F + 
Sbjct: 4   KYDVVVVGAGIAGPIVARNVARAGFSVLLIDKKWAIGT---PKQCAEGIS---IKVFEKY 57

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRS-YININRHAFDLWMKS-LIPASVEVYH 119
            +      I      +         L   Y+    + + R  FD  +      A  +V  
Sbjct: 58  DIPYDKRFINREIYGAKLYSPSGYELEMRYKDVSGVILERKVFDKMLAYYAAKAGADVLA 117

Query: 120 DSLCRKIWREDDKW-HVIFRADGWEQHITARYLVGADGANSMVRRHLY-----PDHQIRK 173
            +    + R+D K   +  + +     I A  +V ADG  S + R        P H+   
Sbjct: 118 RTEALDVIRKDGKVVGIKAKHEDEPIEIYADVIVAADGVESTIARKAGINTYAPPHEFDS 177

Query: 174 YVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKD-GYFIFGGAYPMKDGQTRFTTLKE 232
               +       P   +    +      Y W   KD      G      + QT    L +
Sbjct: 178 SYEYEMLIEGFDPDLIHLWFGNEIAPRGYVWVFPKDEDRANVGIGINSDNPQTAKYYLDK 237

Query: 233 KMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDS 292
            +        K ++     V            K+N  ++G+AA  ++     G++ A+++
Sbjct: 238 WLKENNIPAKKLLEINVGVVPVGG--FVKELVKNNVLVVGDAARQVNPMHGGGMAEAMEA 295

Query: 293 TDILRSVLLKQPEK----LNTAYWRATRKLRLKLFGKIVKSRC 331
             I    ++K  E+    L   Y +   +   K   K++K R 
Sbjct: 296 GTIASKWIVKALEEENLSLLQNYTKEWWETDGKRLEKVLKVRR 338


>UniRef50_UPI0001C15A6F geranylgeranyl reductase n=2 Tax=Nostocaceae RepID=UPI0001C15A6F
          Length = 404

 Score =  216 bits (551), Expect = 9e-55,   Method: Composition-based stats.
 Identities = 62/366 (16%), Positives = 113/366 (30%), Gaps = 40/366 (10%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M ++DV + G GPAG+  A   A   ++V  ++K          K CGG + P    + +
Sbjct: 1   MLNYDVIVCGAGPAGTTAAWMAAKTGLKVALIEKYPL----PRHKTCGGGM-PAVLGNLL 55

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRS-----YININRHAFDLWM-KSLIPA 113
            D +   V       +      D       N   S        + R  FD  + +    A
Sbjct: 56  PDLVPEAVVACQVNYMRHTWKFDHPILGAINPPGSEPELKLWMVQRSVFDNALARQAAQA 115

Query: 114 SVEVYHDSLCRKIWREDDKWHVIFRA-------DGWEQHITARYLVGADGANSMVRRHLY 166
             ++      + +  +     V  R+        G E    A Y++GADGAN +  +   
Sbjct: 116 GADLRDGLAVKSLEMDSHGVIVRARSFKSDSGIGGGEFVAYAPYVIGADGANGITAKIAN 175

Query: 167 PDHQIRKYVAIQQWFAE-------KHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYP 219
              +    +A++  +         K   P    +   ++ N Y W   K+ +   G    
Sbjct: 176 LRRERTMALAMEVEYPYNWTQDHPKDLRPDVIHLEYGAVPNGYGWIFPKEDHLNVGAGLF 235

Query: 220 MKDGQ---------TRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGK--DNA 268
             D +          +      +   F                 P       C       
Sbjct: 236 RPDRRDCRSDHSIRAQLQQAICQYLDFMDISYNPELIRFHGHPLPIWDGREKCHTPDGKI 295

Query: 269 FLIGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVK 328
            L G+AAG I+    +GI +A+ S  +    +        ++Y +         F   ++
Sbjct: 296 LLAGDAAGLINPFFGDGILHAVKSGMLAAECVATS---ATSSYTQRIHHEFAANFDAALQ 352

Query: 329 SRCLTA 334
                 
Sbjct: 353 MARFYY 358


>UniRef50_Q8DGN7 Tlr2279 protein n=5 Tax=Cyanobacteria RepID=Q8DGN7_THEEB
          Length = 375

 Score =  216 bits (551), Expect = 1e-54,   Method: Composition-based stats.
 Identities = 67/348 (19%), Positives = 111/348 (31%), Gaps = 22/348 (6%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           +D  ++G GPAG + A  LA + + + + +K         KPC G ++P   + F  D  
Sbjct: 5   YDCIVVGSGPAGGSAAYHLARRQRSVLVLEKAAL---PRQKPCTGGISPVIGQWFDVDFQ 61

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIP-ASVEVYHDSL 122
               D     + +S K  D       +       + R  FD ++          V   + 
Sbjct: 62  PAIADTTRTVR-YSWKFKDA-VEAELSIPEPIWIVERTVFDHYLLQQAQQKGAVVADQTE 119

Query: 123 CRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFA 182
              I  + D W V             RYL+ ADGANS + R L    ++ +  A+     
Sbjct: 120 VTGITFQKDHWQVHTATT----TYGGRYLIAADGANSQMARWLGFKPKVGRTAAVMTVPN 175

Query: 183 EKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTT-LKEKMSAFQFQF 241
            +      +      + N Y WS  K      G A      +  +   L++  +  Q Q 
Sbjct: 176 PR--GDRAAHFEFGLVKNGYLWSFPKGDQRTVGVAVVRGSDRPNWEPILQQYCAVHQLQL 233

Query: 242 GKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLL 301
                                    +A L GEAAG +   S EG+  AL S       + 
Sbjct: 234 ADCPIQY---HPLCIWEGQQPLHTHHALLAGEAAGLVDPFSAEGVRPALYSGMRAAEAID 290

Query: 302 KQPE---KLNTAYWRATRKLRLKLFGKIVKSRCLTAPA---LRKWIMR 343
                       Y +  ++          +   L         +  M+
Sbjct: 291 AALGGEVDALATYSKTLQEEWGTDLAWAQRLAGLFHRMPGVGYRLAMK 338


>UniRef50_D2B4C1 Geranylgeranyl reductase n=4 Tax=Actinomycetales RepID=D2B4C1_STRRD
          Length = 425

 Score =  215 bits (549), Expect = 1e-54,   Method: Composition-based stats.
 Identities = 67/376 (17%), Positives = 126/376 (33%), Gaps = 39/376 (10%)

Query: 5   DVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           DV ++G GPAGS  A  LA   + V+ L+K     T    K CG  L P A +  I  G+
Sbjct: 17  DVIVVGAGPAGSTTAFHLAQAGLDVLLLEK----TTFPREKVCGDGLTPRAVKQLIAMGI 72

Query: 64  TLP----VDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKS-LIPASVEVY 118
            +     V       +      ++      +Y    +   R  FD  + +  +   V + 
Sbjct: 73  DIDAPGWVRNKGLRVVGGGLRFELDWPELSSYPDFGLVRTRQDFDEILAANAVRGGVRLL 132

Query: 119 HDSLCRKIWREDDK---WHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRK-- 173
                     +D       V+ + DG E    +R +V ADG ++ +   +    +  +  
Sbjct: 133 QGVNVTAPILDDRSGHIVGVVAKKDGEEVSYRSRLVVAADGNSTRISLAMGLHKREDRPM 192

Query: 174 YVAIQQWFAEKHPVPFYSCIFD-----NSITNCYSWSI-SKDGYFIFGGAYPMKDGQTRF 227
            VA++ +F        Y   +      +++   Y W     DG    G          + 
Sbjct: 193 GVAVRTYFESPRHDDDYLETWLELWDGDTLLPGYGWIFGVGDGTSNVGLGLLNTSESFKG 252

Query: 228 TTLKEKMSAFQFQFGKTVKSEK-------CTVLFPSRWQDFVCGKDNAFLIGEAAGFISA 280
              ++ +  +           +            P  +           L+G+A G I+ 
Sbjct: 253 MDYRDLLRRWVKNMPPEWGYVEENMTTPIRGAALPMAFNRQPHYTRGLVLVGDAGGMINP 312

Query: 281 SSLEGISYALDSTDILRSVLLKQP--------EKLNTAYWRATRKLRLKLFGKIVKSRCL 332
            + EGI+YA+++  I    +++          E++  AY +  +       G     R  
Sbjct: 313 FNGEGIAYAMETGQIAAETIVQALARTTPAQRERVLRAYPQTLKDAYG---GYFTLGRGF 369

Query: 333 TAPALRKWIMRSGVAH 348
                 + +M     H
Sbjct: 370 VELIGHRGVMDFFTRH 385


>UniRef50_P96800 Uncharacterized protein Mbar_A1602 n=1 Tax=Methanosarcina barkeri
           str. Fusaro RepID=Y1602_METBF
          Length = 387

 Score =  215 bits (549), Expect = 2e-54,   Method: Composition-based stats.
 Identities = 83/353 (23%), Positives = 128/353 (36%), Gaps = 26/353 (7%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M+ +DV IIG GPAGS  A  LA  K+ V+ +DK     +    KPC G L   A  SF 
Sbjct: 4   MKKYDVVIIGAGPAGSYAAYMLAKSKINVLVIDKY----SFPRYKPCAGGLTAKAFNSFD 59

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVY 118
              ++  V    N  + S K            +     I R  FD ++ K  + +     
Sbjct: 60  -FPISKEVKYSTNSIVTSYKNQIFHN--ISGNKTLVKMIERKEFDDFLIKKAVDSGATFL 116

Query: 119 HDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQ 178
                 +I  E+ ++ +        +     YL+GADG N +V R      +     A++
Sbjct: 117 DGMKVTEITWENAEFSIKT----DSEFFRCNYLIGADGTNGIVNRTFNIVERDLYGFAVE 172

Query: 179 QWFAEKHPV--PFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSA 236
                       F       ++ N Y W   KD Y   G     +        +++ +  
Sbjct: 173 INCPVSRDNIGKFNMTFDFGTVPNGYLWIFPKDEYVCVGAYTTNRK----MKNIQKYLLD 228

Query: 237 FQFQFGKTVKSEKCTVLFPSRWQDFVCGKD-NAFLIGEAAGFISASSLEGISYALDSTDI 295
           +  + G   +SEK        +       D    L+G+AAGF    + EGI YA+ S  I
Sbjct: 229 YIEKLGLVPESEKLKGHIIPYYGINYKQPDFPCVLVGDAAGFGEYWTGEGIYYAVKSGTI 288

Query: 296 LRSVLLKQPEKL---NTAYWRATRKLR---LKLFGKIVKSRCLTAPALRKWIM 342
              V+    +       A  R  ++     LKL   I K      P     +M
Sbjct: 289 AAEVISSSIKSGIFDRQALQRRYQREIIRGLKLAYYIGKFFYGNLPLSFNLVM 341


>UniRef50_C9RJJ2 Geranylgeranyl reductase n=1 Tax=Fibrobacter succinogenes subsp.
           succinogenes S85 RepID=C9RJJ2_FIBSS
          Length = 395

 Score =  215 bits (549), Expect = 2e-54,   Method: Composition-based stats.
 Identities = 64/353 (18%), Positives = 113/353 (32%), Gaps = 25/353 (7%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
             +DV +IG GP GS  AR L+    +V+ L+K+ + G       CG             
Sbjct: 5   NEYDVVVIGAGPGGSVAARNLSRAGHKVLLLEKREKIGYPVR---CGEASTK--LSDLQT 59

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKS-LIPASVEVYH 119
            G  +  D I               ++    + + I +NR  FD W+        VEV  
Sbjct: 60  YG-PIDEDCIETIINGLYIYGPNGVNIDLAQKGTGIMLNREKFDPWLAHLAANDGVEVVT 118

Query: 120 DSLCR---KIWREDDKWHVIFRADGWE--QHITARYLVGADGANSMVRRHLYPD---HQI 171
            +       +        V       E  + + A+ ++ ADG  S + R +  D      
Sbjct: 119 RARAEFVGDVESGTRLVRVKLGEGAGETTEEVRAKMVIAADGVESRIGRQVGLDCLQKPA 178

Query: 172 RKYVAIQQWFAEKHPVPFYSCIFDN--SITNCYSWSISK--DGYFIFGGAYPMKDGQTRF 227
                +          P Y   +     I + Y WS  K       FG  + + +     
Sbjct: 179 FTCTGVDIQVQGILTKPDYLTFWQGHDFINDGYIWSFPKVKSNVTNFGAGFLISN--NHG 236

Query: 228 TTLKEK-MSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGI 286
           + + +  M      F     +     + P          D   L+G+AA   +  +  GI
Sbjct: 237 SNVLDITMEWLYKLFPGAQINHVVGGVIPVSSVLKDYTLDRFALVGDAAHHTNPLTGGGI 296

Query: 287 SYALDSTDILRSVLLKQPE--KLNTAYWRATRKLRLKLFGKIVKSRCLTAPAL 337
           + A+ +       + +  E   L+  + +   K     FG++          L
Sbjct: 297 AAAMRAGRFCAQTVHEGFECGNLSKEFLKTYEKRCYDYFGRMHDFEYKFRRFL 349


>UniRef50_A8URP5 Putative uncharacterized protein n=2 Tax=Aquificaceae
           RepID=A8URP5_9AQUI
          Length = 387

 Score =  215 bits (549), Expect = 2e-54,   Method: Composition-based stats.
 Identities = 59/346 (17%), Positives = 119/346 (34%), Gaps = 20/346 (5%)

Query: 3   HFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            +D  ++G GPAG++ AR L+   ++V+ L+K+         K C G L+    R     
Sbjct: 9   RYDAVVVGGGPAGASSARFLSEKGLKVLLLEKRKL----PRFKLCAGCLS---VRITPLL 61

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKS-LIPASVEVYHD 120
                 +V+   +   +           + +     I+R +FD ++    + +  +++ +
Sbjct: 62  PTGWESEVLNTIRGGYLGFRGEKFHHKTSGEPVAYIIDRASFDHFLVKSAVESGADLWEE 121

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW 180
           +       +        R    +  +    L+GADG  + V + L    +          
Sbjct: 122 TEFLSFEGDR-----TLRVRTDKGAVETDLLIGADGFYTKVGKQLGYQKRKFFRS---VE 173

Query: 181 FAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ 240
           F  +  +     I    +   Y W   K      G A   +  +     LK+ +   +  
Sbjct: 174 FWTEGDLGEEVVIDIGIVKRGYGWIFPKGDKVSVGLATTGR--ENTLDVLKDYVKRHELL 231

Query: 241 FGKTVK-SEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSV 299
             K VK  +   + + +   +   GK    L+G++A  +     EGI Y +    +L   
Sbjct: 232 KSKEVKGVKGWMIPYLTSPSEAQLGKGRVMLVGDSANLVDPLLGEGIYYGVLGGKLLAES 291

Query: 300 LLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSG 345
           + + P      Y    R+  +       K   L     R   +  G
Sbjct: 292 ITQNPGSPLQTYTDLVRREIIPELVYAGKIARLAYNFQRPAFIMGG 337


>UniRef50_C6PBK9 Geranylgeranyl reductase n=1 Tax=Thermoanaerobacterium
           thermosaccharolyticum DSM 571 RepID=C6PBK9_CLOTS
          Length = 387

 Score =  215 bits (549), Expect = 2e-54,   Method: Composition-based stats.
 Identities = 68/338 (20%), Positives = 117/338 (34%), Gaps = 19/338 (5%)

Query: 4   FDVAIIGLGPAGSALARKL-AGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +DV IIG GPAGS LAR+L A   + + ++K     T    K CGG + P   +      
Sbjct: 2   YDVIIIGGGPAGSTLARRLSAQGYKALLIEK----FTMPRYKACGGGITPRCYKMLD--- 54

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKS-LIPASVEVYHDS 121
           L +   V       + K  +  + +    +     ++R  FD ++    + +  +V+   
Sbjct: 55  LDISDYVEDTTYKIAFKFPNNKSVVLETEKPIIYQVDRTKFDKYLIDKAVESGCDVHDGE 114

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWF 181
                +R+  +  V             R LVGADG NS V       +  +      + +
Sbjct: 115 KFLDFYRDGKEVVVKT----DRGQYKTRILVGADGINSTVAYKANLLNGEKGIALEAEVY 170

Query: 182 AEKHPVP---FYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQ 238
            +K  +        +  N+I   Y W   K      G    +         L   +    
Sbjct: 171 VDKCDIEKVRGEVVVDFNAIKYGYGWVFPKKDRLSIGVGTFLSKTSKIKENLSNMIDENV 230

Query: 239 FQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRS 298
               +  K     + FP+  +D     D   LIG+A       + EGI  A+ + +I   
Sbjct: 231 VGNVEECKIYGHQLSFPNG-KDGTYNNDKVILIGDATRLADPFTGEGIYNAILTANISFD 289

Query: 299 VLLKQPEK--LNTAYWRATRKLRLKLFGKIVKSRCLTA 334
           V+ K        + Y    R+  +       +    T 
Sbjct: 290 VIEKYFNGKCELSEYTERLRREVVSDIKWAHRLSLFTY 327


>UniRef50_O26377 Digeranylgeranylglycerophospholipid reductase 1 n=2
           Tax=Methanobacteriaceae RepID=GGR1_METTH
          Length = 397

 Score =  214 bits (545), Expect = 4e-54,   Method: Composition-based stats.
 Identities = 65/335 (19%), Positives = 111/335 (33%), Gaps = 17/335 (5%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSF-IR 60
             DV +IG GPAGS  A+  A     V+ +DKK + G     K C   ++     S  I 
Sbjct: 7   EVDVLVIGAGPAGSTAAKHAALGGADVLLIDKKSEIGA---PKRCAEGVSIGGLESLGIE 63

Query: 61  DGLTLPVDVIANPQIFSVKTVDVA-ASLTRNYQRSYININRHAFDLWMK-SLIPASVEVY 118
                    +   ++ S    DV   S       +   + R  FD +M      A   + 
Sbjct: 64  PNPRWITKKLDGVRMVSPNGTDVWLTSDKVELPEAGYILERKVFDKFMAMDAARAGSRIM 123

Query: 119 HDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRK----Y 174
             ++   + R DD + V     G +  I AR ++ ADG  S V R    +   R      
Sbjct: 124 VKTIATGMERTDDGYLVSAECMGEKFEIKARIVIAADGPESRVARWAGLNTATRPKDMES 183

Query: 175 VAIQQWFAEKHPVPFYSCIFDNSI-TNCYSWSIS-KDGYFIFGGAYPMKD-GQTRFTTLK 231
            A  +    +         +  S+    Y+  I   D     G      +  ++ +  L 
Sbjct: 184 AAQFEMVGVEMEDNNCIEFYFGSVAPGGYALDIPEGDDIANVGLGVLSTETDKSAYEHLL 243

Query: 232 EKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALD 291
           E + +           E      P          D+  ++G+AAG ++  +  GI   + 
Sbjct: 244 EFVESC-PATRNAQPVELNIGGDPVGGMPKKLVADSLMVVGDAAGQVNPLTGGGIISGMK 302

Query: 292 STDILRSVLLKQPEKLNTAYWR--ATRKLRLKLFG 324
              +   V      + +    R     +L  +  G
Sbjct: 303 GGMLAGQVAAAAVSEGDVTARRLGEYERLCREEIG 337


>UniRef50_Q6L0M1 Digeranylgeranylglycerophospholipid reductase n=6 Tax=Euryarchaeota
           RepID=GGR_PICTO
          Length = 397

 Score =  213 bits (543), Expect = 7e-54,   Method: Composition-based stats.
 Identities = 60/366 (16%), Positives = 123/366 (33%), Gaps = 30/366 (8%)

Query: 1   ME-HFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRS- 57
           ME ++DV +IG GPAGS+ AR  A   ++ + ++K+   G+      CG  ++       
Sbjct: 1   MEVNYDVLVIGAGPAGSSAARFAARKGLKTLLIEKRPDIGSPVR---CGEGVSKSWMPEV 57

Query: 58  -FIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKS-LIPASV 115
               +   +  +V         +   +  +           + R  FD  + +       
Sbjct: 58  ELKPEDHWISDEVKGARIYGPSEKKPIMLTAENAGNEVGYVVERDKFDKHIAALAASEGA 117

Query: 116 EVYHDSLCRKIWREDDK-WHVIFRADGWEQHITARYLVGADGANSMVRRHLYPD----HQ 170
           +V+  S    + ++ ++      R +     + A+ ++ ADG  S   R          +
Sbjct: 118 DVWVKSPALSVIKDGNRIVGAKVRHNSEIVDVRAKMVIAADGFESEFGRWAGLKSLILAK 177

Query: 171 IRKYVAIQQWFAEKHPVPFYSCIFDNS-ITNCYSWSISKDGY-FIFGGAYPMKDGQTRFT 228
                 ++           Y+  +  S     Y W   K  +    G    +   + RF 
Sbjct: 178 NDIISCVEYRMINVDSDEDYTDFYLGSCAPAGYIWVFPKGKHEANVGIGVTISKMRDRF- 236

Query: 229 TLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFL-----IGEAAGFISASSL 283
            +K  + AF         S+  T+   +        +D   L     +G+AA  I   + 
Sbjct: 237 DVKNYLDAFIKSHPG--YSKGKTIQLITGGVSVSKVRDKFTLPGLLTVGDAARLIDPITG 294

Query: 284 EGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMR 343
            GI+  + S      V  K  +           +  +  + ++VK +      LR W  +
Sbjct: 295 GGIANGMISGKYAAEVSKKAIDN------EDYSQEMMNNYERMVKDKFERKH-LRNWFAK 347

Query: 344 SGVAHI 349
             +  +
Sbjct: 348 EKLGTL 353


>UniRef50_D2RHK2 Geranylgeranyl reductase n=2 Tax=Archaeoglobaceae
           RepID=D2RHK2_ARCPR
          Length = 386

 Score =  213 bits (543), Expect = 8e-54,   Method: Composition-based stats.
 Identities = 59/327 (18%), Positives = 104/327 (31%), Gaps = 18/327 (5%)

Query: 16  SALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQ 74
           S  A+  A   + V+ ++K+ + G       C   ++ DA   F+          +   +
Sbjct: 14  SIAAKTCAENGLNVLLVEKRQEIGVPVR---CAEGISRDALERFVEPKKFFISREVVGAK 70

Query: 75  IFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLI-PASVEVYHDSLCRKIWREDDKW 133
           IF+    ++  S  +        + R  FD ++ +L   A  EV   +      R+D   
Sbjct: 71  IFAPDGTEITLSEEKAGNEVGYVLERKVFDRYLATLASQAGAEVLVKTTAYDFERKDGIV 130

Query: 134 HVIFRADGWEQHITARYLVGADGANSMVRRHLYPD---HQIRKYVAIQQWFAEKHPVPFY 190
            V  R  G E  +  + ++GADG  S V +    D           +Q         P Y
Sbjct: 131 KVKLRRMGEEWEVETKLVIGADGVESRVAKFFGIDTTLKPDGIESCVQYLMTNIDFDPDY 190

Query: 191 SCIFDNS--ITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKTVKSE 248
              +         Y W   K      G        +       +     +F  G+ V+  
Sbjct: 191 CYFWLGKSIAPGGYIWLFPKRVGANVGIGVMPSIAKKTPKEYLDDFVQKKFPDGRIVEL- 249

Query: 249 KCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQ----- 303
                 P   +      DN  L+G+AA      +  GI+ A+ +      V  +      
Sbjct: 250 -VAGAVPVCGEIKTAVADNVMLVGDAARHADPITGGGIANAMKAGYYAGKVAAEAVKKND 308

Query: 304 -PEKLNTAYWRATRKLRLKLFGKIVKS 329
              K    Y +  ++   K   K  K 
Sbjct: 309 FSAKFLKRYDKLWKEDFGKELAKKRKL 335


>UniRef50_A0LRI0 Geranylgeranyl reductase n=38 Tax=Actinomycetales
           RepID=A0LRI0_ACIC1
          Length = 445

 Score =  213 bits (542), Expect = 1e-53,   Method: Composition-based stats.
 Identities = 72/383 (18%), Positives = 139/383 (36%), Gaps = 40/383 (10%)

Query: 5   DVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           DV ++G GPAGS  A  LA     V+ L+K          K CG  L P A R  +R G+
Sbjct: 34  DVVVVGAGPAGSTTAAYLAQAGVDVVVLEKSA----FPREKVCGDGLTPRAVRQLVRLGI 89

Query: 64  TL-----PVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEV 117
                   +       +     +++      ++    +   R  FD  + +        V
Sbjct: 90  DTSAQAGWLRNKGLRILGGGMRLELPWPELASFPDYGLVRPRTDFDQLLARHAAKLGAVV 149

Query: 118 YHDSLCRKIWREDD---KWHVIFRADGW-EQHITARYLVGADGANSMVRRHLYPDHQIRK 173
           +  +       +D       V+  A+G     +    +V ADG +  +   +  D   R+
Sbjct: 150 HERTPVSAPLIDDRTGRVVGVVATAEGERPLVVRGSVVVAADGNSGRLALAVGRDRLPRR 209

Query: 174 --YVAIQQWFAEKHPVPFYSCIFD-----NSITNCYSWSIS-KDGYFIFGGAYPMKDGQT 225
              VA ++++A +     +   +        +   Y W     DG    G          
Sbjct: 210 PMGVAYRRYYASRRHDDTWLESWLELRDGGRLLPGYGWIFGMGDGTSNVGVGILNTSSAF 269

Query: 226 RFTTLKEKMSAF----QFQFGKTVKSEKCTV---LFPSRWQDFVCGKDNAFLIGEAAGFI 278
           R    +  +  +      ++G T ++ +  +     P  +       D   L+G+AAG I
Sbjct: 270 RNIDYRALLRRWVAGMPAEWGITEETAQGPIRGAALPMGFTRKPQYADGLLLVGDAAGMI 329

Query: 279 SASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKS--------- 329
           +  + EGI+YA++S      ++++   K   A    T +   ++  +             
Sbjct: 330 NPCNGEGIAYAMESGAAAAEIIVQALAKPTGAARERTLRSYPRVLAEQYGGYYTLGRWFV 389

Query: 330 RCLTAPALRKWIMRSGVAHIPQL 352
           + +  P + +++ R G+ H PQL
Sbjct: 390 QLIGKPGVMRFLTRHGLPH-PQL 411


>UniRef50_B3QNV5 Geranylgeranyl reductase n=4 Tax=Chlorobiaceae RepID=B3QNV5_CHLP8
          Length = 399

 Score =  212 bits (540), Expect = 2e-53,   Method: Composition-based stats.
 Identities = 74/375 (19%), Positives = 129/375 (34%), Gaps = 37/375 (9%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M+ FDV I G GPAG   A  LA   ++V  +DK          K CG  + P + R   
Sbjct: 1   MKPFDVVISGAGPAGCTAALSLARKGLRVALIDK----AQFPRDKTCGDGVTPASVRLLE 56

Query: 60  RDGLTL-------PVDVIANPQIFSVKT--VDVAASLTRNYQRSYININRHAFDLWMKSL 110
             G+         P+ V     +FS     V    S T +       I R   D    + 
Sbjct: 57  ELGVVEVVRQRVGPLTVFKGITLFSPDGAVVQGRLSQTGDRSSESYVIPRSLLDDCFVTC 116

Query: 111 IPAS--VEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYP- 167
           + A   +  + ++  R++    D    +  + G       + +V ADG  S +   L   
Sbjct: 117 VKAHESISFFDNTESRELIINGDSARGLSTSGG---EFYGKCIVAADGVYSPIAAQLGLL 173

Query: 168 -DHQIRKYVAIQQWFAEKHPVPF-YSCIFDNSITNCYSWSIS-KDGYFIFGGAYPMKDGQ 224
              + ++  A++ +F+  + +       +DN I   Y W     +     G     +  +
Sbjct: 174 NRQKEQQGFAMRAYFSNVNGLSDSIELHYDNLILPGYGWVFPAGEKRANIGVGIMTRFKE 233

Query: 225 TR-----FTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFV--CGKDNAFLIGEAAGF 277
            R     F     +      +             +P  +  F     + N  L G+A  F
Sbjct: 234 PRGLKNMFKRFVAENPVVSSKLKDAAMEPGTLKAWPLPFGSFRGMRSQRNVLLAGDAGSF 293

Query: 278 ISASSLEGISYALDSTDILRSVLLKQPEKLNTA-----YWRATRKLRLKLFGKIVKSRCL 332
           +   S EGI YA+ S       ++K   + + A     Y +  RK     F +      L
Sbjct: 294 VDPLSGEGIFYAIKSGQFAADAIVKALAENDRAQAGAFYEKLWRKAF--EFDEFSVGYFL 351

Query: 333 TAPALRKWIMRSGVA 347
                 +++M + + 
Sbjct: 352 QTMLNSRFLMETLLQ 366


>UniRef50_O27753 Digeranylgeranylglycerophospholipid reductase 2 n=1
           Tax=Methanothermobacter thermautotrophicus str. Delta H
           RepID=GGR2_METTH
          Length = 385

 Score =  211 bits (539), Expect = 2e-53,   Method: Composition-based stats.
 Identities = 66/350 (18%), Positives = 111/350 (31%), Gaps = 29/350 (8%)

Query: 3   HFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            +DV +IG   AGS  A   A   + V+ L++  + GT      C G ++      F   
Sbjct: 2   KYDVVVIGGRVAGSTAAYHAARLGLSVLLLERNPEIGT---PVQCAGGVSDS---FFKST 55

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRS-YININRHAFDLWMK-SLIPASVEVYH 119
           GL    +        +     + A +           + R + D ++      A  +V  
Sbjct: 56  GLKPLPEFTCTRIRAAAVNGPLGARIVTENPVVRGYILERKSLDKYLALRAAEAGADVLT 115

Query: 120 DSLCRKIWREDDKW-HVIFRADGWEQHITARYLVGADGANSMVRRHLYPD---HQIRKYV 175
            S+   +   +     V+FR     Q +    ++ ADG  S + R    +          
Sbjct: 116 MSIAGDLIFREGSVSGVVFRGPDGVQEVECGMVIAADGVQSSIARKAGLETGFRPADLCS 175

Query: 176 AIQQWFAEKHPVPFYSCIFDNS--ITNCYSWSISKD-GYFIFGGAYPMKDGQTR--FTTL 230
            +Q   A     P     +  S    + Y W   K  G    G     K    R   + L
Sbjct: 176 CVQYEVAGVDVDPETMEFYFGSRFAPSGYLWVFPKGEGRANVGLGIRRKSCSERGPLSYL 235

Query: 231 KEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYAL 290
              M    F+     + E      P          D   ++G+AAG +   +  GI  A 
Sbjct: 236 NRFMEERGFK-----RIEFNAGAVPVCGPIERTFTDGLLVVGDAAGQVDPLTGGGIHLAA 290

Query: 291 DSTDILRSVLLKQPE------KLNTAYWRATRKLRLKLFGKIVKSRCLTA 334
           +   I   V  +  E      +  + Y    RK   K   + +K R +  
Sbjct: 291 ECAKIAGEVAAEAIESGRVDGRFLSRYEMRWRKKIGKNLERSLKFRKILD 340


>UniRef50_A6CDB5 Geranylgeranyl reductase n=1 Tax=Planctomyces maris DSM 8797
           RepID=A6CDB5_9PLAN
          Length = 375

 Score =  211 bits (538), Expect = 3e-53,   Method: Composition-based stats.
 Identities = 76/338 (22%), Positives = 120/338 (35%), Gaps = 31/338 (9%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           E  DV I+G GP GS+ A  L    + V+ LD+     T    K C G + P        
Sbjct: 4   ESCDVLIVGGGPGGSSCAWGLQDSGLDVLILDQ----ATFPRDKVCAGWITPAVTDLLNL 59

Query: 61  DGLTLPVDVIANPQ-IFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYH 119
           D        +  P   F    +  AA  T   Q     I R  FD ++ S          
Sbjct: 60  DLSDYQKSHVLQPITRFRTGIIGGAAVQTEFTQTVSYGIRRCEFDEYLLSRC--GARTRL 117

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQ 179
               + + R ++ W V          + A+ +VGA G    V R L P+ +    V + Q
Sbjct: 118 GEKFQSLERTENGWLV-------NGSLQAKVIVGAGGHFCPVARWLNPEKRSEHSVVLAQ 170

Query: 180 W---------FAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTL 230
                            P    ++ +     Y+W   KDGY   G     ++G+ + +  
Sbjct: 171 ETEFQLTPEQLKVCRVQPERPELYFSPDLRGYAWCFLKDGYLNVGIG---REGEKQLSAA 227

Query: 231 KEKMSAFQFQFGKTVK----SEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGI 286
           +++   F    G+  +      K         +      D   LIG+AAG  S  S EGI
Sbjct: 228 RDEFIQFLDLEGRVPRGILGKFKGHAYRLYGLEKRSVVDDRILLIGDAAGLASPQSGEGI 287

Query: 287 SYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFG 324
             A++S  +   VL +     +  + +   +  L  FG
Sbjct: 288 RPAVESGLMAADVLQQCQSSYHIQHLQNYEQKILDRFG 325


>UniRef50_B3QWR4 Geranylgeranyl reductase n=1 Tax=Chloroherpeton thalassium ATCC
           35110 RepID=B3QWR4_CHLT3
          Length = 382

 Score =  211 bits (537), Expect = 4e-53,   Method: Composition-based stats.
 Identities = 70/374 (18%), Positives = 129/374 (34%), Gaps = 30/374 (8%)

Query: 1   MEHFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M+  +V ++G GPAGS  A  LA     V+ LDK          K CG  +   A     
Sbjct: 1   MQT-EVLVVGAGPAGSTAAAILAQKGYDVLILDK----TEFPRQKACGDGIPHSAIALLD 55

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAA---SLTRNYQRSYININRHAFDLWMKSLIPASVE 116
           + GL          +I             S+    + ++   +R  FD  + S    S  
Sbjct: 56  QLGLHDQFRNTKRNEITGATIHSPRGQQSSINFRMRDNFFIQSRSVFDHTLFSHALTSGA 115

Query: 117 VYHDSLCRK-IWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQ--IRK 173
            +  +   + I  +     V  R    E+ I A   + ADG +S +   L  + Q    +
Sbjct: 116 KFLKAKALEPILNQGKVVGVKARVQDEEKRIFAPITIAADGVDSAIAAPLRREKQLAKHR 175

Query: 174 YVAIQQWFAEKHPVPFYSC-IFDNSITNCYSWSISKDG-YFIFGGAYPMKDGQTRFTTLK 231
            ++++ + +  +  P      F   I   Y W           G    M        ++K
Sbjct: 176 AISLRGYISGLNLNPRTVEGFFPKEIVPGYLWIFPLGEKEANIGLGMRMDKYAKVGMSMK 235

Query: 232 EKMSAF--------QFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSL 283
           + +  F        + +    +   + + +  +  +      D A L+G+AA  +S  + 
Sbjct: 236 QVLQNFLASPEIKARLEPNWQLSDVRASPMNFASQKGIQLAYDGAVLVGDAASLVSPLTG 295

Query: 284 EGISYALDSTDILRSVLLKQ------PEKLNTAYWRA-TRKLRLKL-FGKIVKSRCLTAP 335
            GI  A+ S       +          EK  + Y R     +R ++    +V++   T P
Sbjct: 296 GGIYNAMFSAKTAAETIHDAFQKNDFSEKKLSEYERRCWAAIRYEMKITYVVQNAISTFP 355

Query: 336 ALRKWIMRSGVAHI 349
            L + +M+      
Sbjct: 356 FLIEGLMKFVDNRT 369


>UniRef50_Q8TUV8 Digeranylgeranylglycerophospholipid reductase 2 n=2
           Tax=Methanopyrus kandleri RepID=GGR2_METKA
          Length = 396

 Score =  210 bits (536), Expect = 5e-53,   Method: Composition-based stats.
 Identities = 63/351 (17%), Positives = 103/351 (29%), Gaps = 28/351 (7%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            FDV ++G GPAGS  A   A     V+ L++K + G     K C   ++          
Sbjct: 2   EFDVVVVGAGPAGSVAAWAAAEAGCDVLILERKAEIG---VPKQCAEGISAHG---LEHA 55

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMK-SLIPASVEV-YH 119
           G+    + IA     ++                   + R  FD W+    + A  EV   
Sbjct: 56  GIEPQDEWIATEISRALIYAPNGKEFEV--PGDGYVLERRVFDKWLVVRAVEAGAEVELL 113

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPD---HQIRKYVA 176
               R +  E     V +  +     + AR ++ ADG  S + R          +     
Sbjct: 114 AHARRALLDEGRVVGVEYEGEDGVHEVRARIVIAADGIESRIGRTAGLVPSLKPVEMCTC 173

Query: 177 IQQWFAEKHPVPFYSCIFDNS--ITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKM 234
            Q            +  F ++      Y W   K       G             LK   
Sbjct: 174 AQYEMVGVDVEEDATHFFVDAEFFPGGYFWIFPKGEGRANVGLGIRGSESEPGDALKVLN 233

Query: 235 SAFQFQ------FGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISY 288
            A +            V  E      P          D   L+G+AA  ++  +  G+  
Sbjct: 234 RALEDHELISEAVADAVPVEVNVGGVPVCGPVERTYGDGILLVGDAARQVNPLTGGGLHT 293

Query: 289 ALDSTDILRSVLLKQPEK------LNTAYWRATRKLRLKLFGKIVKSRCLT 333
           +L    I   V  +  E+          Y     +   K F   +K+  + 
Sbjct: 294 SLVCGRIAGEVAAEAIEEDDTSASFLKRYQDRWEEEFGKTFKYALKASKIF 344


>UniRef50_B4CWA5 Monooxygenase FAD-binding n=1 Tax=Chthoniobacter flavus Ellin428
           RepID=B4CWA5_9BACT
          Length = 433

 Score =  209 bits (532), Expect = 1e-52,   Method: Composition-based stats.
 Identities = 54/356 (15%), Positives = 115/356 (32%), Gaps = 35/356 (9%)

Query: 1   MEH-FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M   +DVAIIG GPAGS  A  LA   + + + ++ +          G  L P +   F 
Sbjct: 1   MNEIYDVAIIGGGPAGSTAACLLARAGRRVVVLEREKFPRFHI----GESLLPYSMPVFD 56

Query: 60  RDGLTLPVDVIANPQIFS-VKTVDVAASLTRNYQRSY-------ININRHAFDLWMKS-L 110
           R G+   +D  A P+  + + T    + +  +++  +         + R  FD  +    
Sbjct: 57  RLGIREELDRTAQPKHGAELITACGTSHVIFHFRDGFRLAHHRSYQVERAGFDKLLLDNA 116

Query: 111 IPASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQ 170
             +  E+  +   + +  +DD   V          +  RY++ A G ++++         
Sbjct: 117 AKSGAEIREEVAVQGVDFDDDGATVRLAGPDAP-TLRTRYVIDASGRHTVIGAQQGLKKS 175

Query: 171 IRKY--VAIQQWF---AEKHPVPFYSCIFDNSITNCYSWSISKDGY-FIFGGAYPMKDGQ 224
                  A+   +            +        + + W I         G      + +
Sbjct: 176 YAHLNKFAVFAHYENVRRPPGEDGCTLTRMVRARDRWFWVIPLSDTKTSIGMVTDTTNFK 235

Query: 225 TRFTTLKEKMS-------AFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGF 277
               + ++ +         F        +           ++          L G+AAGF
Sbjct: 236 QWKMSPEDALELGFREQPHFTDILASAKRVTPVYTTGDYSYRSTRLVGPRWMLAGDAAGF 295

Query: 278 ISASSLEGISYALDSTDILRSVLLKQPEKLNTA------YWRATRKLRLKLFGKIV 327
           I      G+  A+ S +     +    ++          Y +   ++ + L+ + V
Sbjct: 296 IDPVFSTGVFLAIASGEQAADAIHISLDRPGKRAGLFAVYEKRLNRV-MDLYLRFV 350


>UniRef50_C9R7U9 Geranylgeranyl reductase n=1 Tax=Ammonifex degensii KC4
           RepID=C9R7U9_AMMDK
          Length = 375

 Score =  209 bits (532), Expect = 1e-52,   Method: Composition-based stats.
 Identities = 62/343 (18%), Positives = 115/343 (33%), Gaps = 23/343 (6%)

Query: 6   VAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTL 65
           V ++G GPAG+  A  LA     + L +K         KPCGG L P A           
Sbjct: 7   VIVVGAGPAGALCACSLARAGLSVLLLEKTH---FPREKPCGGGLTPKAAALLPFSF--- 60

Query: 66  PVDVIANPQIFSVKTVDVAASLTRNYQRS-YININRHAFDLWMKSLIP-ASVEVYHDSLC 123
              V+      ++  +    +L  N+ R     + R   D  +      A   +      
Sbjct: 61  -QSVVEGEVKRAILCLPGVEALEINWDRPVCFLVRREILDTHLAEQARQAGAFLREGEEV 119

Query: 124 RKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAE 183
            +I    +   V            A+ ++GADGA S V R +   +     +A       
Sbjct: 120 VRIEETGEAVTVTT---AGGASYRAQLVIGADGALSRVARLVGRPYPRHFALAAALIPPP 176

Query: 184 KHPVPFYSCIFD-NSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFG 242
                  + + D  ++   Y W   K  +   G        + RF         F  + G
Sbjct: 177 AWAEKRDTILIDLEALPYGYGWVFPKIDHLNAGVGSFAATRELRF-----YWENFLRRNG 231

Query: 243 KTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLK 302
                           ++   G+    L+G+AAG +   + EG+  A  S ++    +L+
Sbjct: 232 LARPFRLRAHPLALAGKETELGRGRVMLLGDAAGLVDPLTGEGLYAAFRSAELAARAILE 291

Query: 303 Q--PEKLNTAYWRATRKLRLKLFG---KIVKSRCLTAPALRKW 340
           +   E+  + Y    +   L+ +    ++ +      P + ++
Sbjct: 292 KGVGERAVSRYRELVKASLLREYHFAYRLARLFYRFLPLIARY 334


>UniRef50_B9L6H5 Geranylgeranyl hydrogenase n=2 Tax=Nautiliaceae RepID=B9L6H5_NAUPA
          Length = 324

 Score =  209 bits (532), Expect = 2e-52,   Method: Composition-based stats.
 Identities = 75/347 (21%), Positives = 126/347 (36%), Gaps = 43/347 (12%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           M+   + IIG GPAGS  ARKLA    V  +  K         KPCGG +   A + F  
Sbjct: 1   MK---IVIIGGGPAGSTAARKLAPFYHVTLIQDKLDF-----DKPCGGGIKTKAFKEFD- 51

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHD 120
               +P  +I +     +              ++   + R  FD  ++ L   +      
Sbjct: 52  ----IPNKLIKHSLDHVIMKYKNTTVKVDLNGKNLSIVKRDEFDKKLRDLAQQAGAKIIY 107

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW 180
              + +         I + D    ++    L+ ADG NS VR+ L          A    
Sbjct: 108 GRFKTVKNN----KAIIKTDNSILNLDYDILIAADGVNSTVRKALNLPK----IPATITH 159

Query: 181 FAEKHPVPFYSCIFDNSI---TNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAF 237
           +A        +C F          Y+W+   +     G        +  F  L   ++  
Sbjct: 160 YARIDQYKVQTCEFFFDFDIGGEYYAWAFPHENLTHIGTV-----SRGNFENLCRYLNVK 214

Query: 238 QFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILR 297
               G            P+  ++ +  K+N + +G+AAG +   S EGI YA+ S D+L 
Sbjct: 215 AKPKGYK---------IPTWQENIIIQKNNVYFVGDAAGQVMPLSFEGIYYAIKSADLLA 265

Query: 298 SVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRS 344
           + +L+     N  Y     K   K F  + K   L    +R +++++
Sbjct: 266 NCILE-----NKNYPNEWNKRFFKEFSLMKKLEALNKTFIRGFVVKA 307


>UniRef50_A0QR89 Geranylgeranyl reductase n=7 Tax=Mycobacterium RepID=A0QR89_MYCS2
          Length = 395

 Score =  207 bits (527), Expect = 5e-52,   Method: Composition-based stats.
 Identities = 66/372 (17%), Positives = 118/372 (31%), Gaps = 29/372 (7%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           + +D+ I G GP+GSA A + A    +V+ LDK          KPCG  L   A     +
Sbjct: 3   QRYDLVIAGGGPSGSAAAWQAAQTGAKVVVLDKAE----FPRDKPCGDGLTARAVSYLQK 58

Query: 61  DGLTLPVD---VIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDL-WMKSLIPASVE 116
            GL   V     +    +FS    +++             ++R   D   +K    A  E
Sbjct: 59  MGLADEVATYHRVNRVTVFSPSEWELSFPRRPGMPDHGHTVSRTHLDTVLLKHAESAGAE 118

Query: 117 VYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVA 176
           V   +       + +   +       E+ +    ++ ADGA S ++R L  D +   Y A
Sbjct: 119 VRQGAEVAGPEFDANGRVIGVVLKSGEK-VYGDAVIAADGAYSPIKRALKIDSEYNGYSA 177

Query: 177 IQQWFAEKHPVPFYS-------CIFDNSITNCYSWSIS-KDGYFIFGGAYPMKDGQTRFT 228
           I          P           +F       Y W     +G F  G  Y       +  
Sbjct: 178 IAIRSEMHANRPDSDSLDIYLKLVFQGDQLPGYGWVFPMGNGMFNIGLGYVNSYKNWQSI 237

Query: 229 TLKEKMSAFQFQFGKTVKSEKC----------TVLFPSRWQDFVCGKDNAFLIGEAAGFI 278
              + +  F     +  +                  P  +  +   +      G++ G  
Sbjct: 238 NATQFLGEFLRSLPREWELPPIEELKKNKSVRAWRLPMGFTAWPPWRPGVLFTGDSLGAG 297

Query: 279 SASSLEGISYALDSTDILRSVLLKQP-EKLNTAYWRATRKLRLKLFGKIVKSRCLTAPAL 337
             +S  GIS AL+S        +          +    +++      +  + R +     
Sbjct: 298 KPASGAGISKALESGLAAGECAIAALQNGGPDDFTNYAQRMEAAWGREYRRGRYMHKLIG 357

Query: 338 RKWIMRSGVAHI 349
           +  +  +GV  I
Sbjct: 358 KPKLAEAGVKLI 369


>UniRef50_Q6L1J9 Geranylgeranyl hydrogenase n=3 Tax=Thermoplasmatales
           RepID=Q6L1J9_PICTO
          Length = 379

 Score =  206 bits (525), Expect = 9e-52,   Method: Composition-based stats.
 Identities = 65/329 (19%), Positives = 108/329 (32%), Gaps = 29/329 (8%)

Query: 5   DVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           DV I+G GPAGS  A  L+ K   V+ L++  + G       C GL++            
Sbjct: 3   DVIIVGAGPAGSYAAYLLSKKGFDVLQLEEHREIG---KPVECTGLVSKRVFSMVRS--- 56

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKS-LIPASVEVYHDSL 122
                 + N    +         +  +     I + R  FD  + +  I    ++  ++ 
Sbjct: 57  ----RSMINKVHGANVYFPNNKYIHVSKNEETIVMYRDQFDKDVAAMAIENGTDLRINAR 112

Query: 123 CRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW-- 180
                  DD   V FR +G  Q    + ++GADG NS VRR L  +   R     Q    
Sbjct: 113 AIDASVNDDFASVKFRENGKIQEEKTKIIIGADGVNSTVRRLLSNERPSRIISTYQVDSS 172

Query: 181 FAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ 240
           +           +  +S    + W++        G           F  + +        
Sbjct: 173 YKMDDQDDVNVYLGSSSSRGFFGWAVPSGDITRIGVGADHDTAIKYFKNINKNF------ 226

Query: 241 FGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTD---ILR 297
                         P R+     GK    L+G+AAG +   S  GI   + S     I  
Sbjct: 227 --NDKILGINGSPIPIRYLKKTYGK-RYMLVGDAAGIVKPLSGGGIYTGMISGKNAAIAA 283

Query: 298 SVLLKQ---PEKLNTAYWRATRKLRLKLF 323
             ++ +    EK  + Y +  R    +  
Sbjct: 284 ESIIDREDFSEKSMSLYQKLWRSEIGREL 312


>UniRef50_Q12X19 Geranylgeranyl reductase n=1 Tax=Methanococcoides burtonii DSM 6242
           RepID=Q12X19_METBU
          Length = 399

 Score =  205 bits (523), Expect = 1e-51,   Method: Composition-based stats.
 Identities = 55/337 (16%), Positives = 113/337 (33%), Gaps = 16/337 (4%)

Query: 4   FDVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +DV ++G GP GS  AR       +V+ +++    G+      C GLL+  A        
Sbjct: 3   YDVVVVGAGPTGSTAARYATMGGAKVLIIEEHFSIGS---PVECTGLLSTRAVSECD--- 56

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRS-YININRHAFDLWMKS-LIPASVEVYHD 120
           +    D + N    +         L  + +R+    ++R  FD  + S  +    E+   
Sbjct: 57  VRPEDDFVLNSVRGAFVNSPNGTCLPIDGKRTKAYVVSRKIFDRHLVSLAVDTGAELMLK 116

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW 180
                I ++D    +     G    + ++ ++GADG  S V R+       R    +Q  
Sbjct: 117 GRVTGIQQKDGIQLLSVIHMGKMITVRSKVVIGADGVKSNVARYTGLGKVDRILSGVQIE 176

Query: 181 FAEKHPVPFYSCIFDNS-ITNCYSWSISKDGYFI-FGGAYPMKDGQTRFTTLKEKMSAFQ 238
                    +  +F  S     ++W++  +      G A    +       L++ ++  +
Sbjct: 177 AVYSSNDTDFVELFVGSQAPGFFAWTVPVNERISRIGLAVEPGNEHNAINYLRKIVNKNK 236

Query: 239 FQFGKTVK--SEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDIL 296
              G       +      P          D   + G+AAG +  +S  G+        + 
Sbjct: 237 HLAGNCTNNMLDLVVGGIPIGPLKRTY-SDGILIAGDAAGQVKPTSGGGVYTGAVCAKMA 295

Query: 297 RSVLLKQ--PEKLNTAYWRATRKLRLKLFGKIVKSRC 331
             V  +    E  +    +          G+ +++  
Sbjct: 296 GQVAAEAVSEENFSANRLKEYESRWKSALGRELRTGM 332


>UniRef50_A5D5E0 Dehydrogenases n=1 Tax=Pelotomaculum thermopropionicum SI
           RepID=A5D5E0_PELTS
          Length = 401

 Score =  205 bits (522), Expect = 2e-51,   Method: Composition-based stats.
 Identities = 66/350 (18%), Positives = 107/350 (30%), Gaps = 21/350 (6%)

Query: 1   MEHFDVAIIGLGPAGS-ALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M  +DV +IG GPAG            +V+  ++  + GT      C GL++P   ++  
Sbjct: 1   MN-YDVIVIGGGPAGCKTAGLIAGKGYRVLVAEEHPRIGT---PVQCAGLVSPRTLKA-- 54

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSY-ININRHAFDLWMKSLIP-ASVEV 117
                +P  VI N             +L    + +    I+R  FD  +      A  E+
Sbjct: 55  ---AGMPDGVIINEIKGVYVHSPGGETLAVRCKDAAAFVIDRAGFDRKLAERAQSAGAEI 111

Query: 118 YHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAI 177
                        +K  V  ++   E    AR ++GADGANS V R +            
Sbjct: 112 LTGVKAGLGKLLAEKIIVKLKSSRGESSARARLVIGADGANSRVARRINAPRSGEVVRMF 171

Query: 178 QQWFAEKHPVPFYSCIFDNS--ITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMS 235
                 K P    + IF         + W I  DG     G       +           
Sbjct: 172 AAEVQLKCPEEDMAHIFLGREIAPGWFGWLIPVDGRRARAGIGVCGVDKHPREYFYRLAE 231

Query: 236 AFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDI 295
           A +  F             P          D   L+G+AA      S  G+   +   ++
Sbjct: 232 ARRDIFKDMKVICYTGGAVPIGLP-PRIYGDRILLVGDAACQTKPISGGGLYLGMRGAEL 290

Query: 296 LRSVLLKQPEKLN------TAYWRATRKLRLKLFGKIVKSRCLTAPALRK 339
              V  K   + +      + Y R   K         ++ R +      +
Sbjct: 291 CAKVATKALSREDLSAERLSEYQRRWEKEMAGETQTALRHRRVFLTMSDR 340


>UniRef50_B1L612 Geranylgeranyl reductase n=1 Tax=Candidatus Korarchaeum cryptofilum
           OPF8 RepID=B1L612_KORCO
          Length = 368

 Score =  205 bits (521), Expect = 3e-51,   Method: Composition-based stats.
 Identities = 61/335 (18%), Positives = 113/335 (33%), Gaps = 23/335 (6%)

Query: 4   FDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +D  +IG GP+GS  A  LA    + + LD K         K CGG +   A       G
Sbjct: 2   WDAIVIGAGPSGSVTAYLLAKKGYKTLILDMKD----FPRYKSCGGGVTWRAYNLLRELG 57

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSL 122
           + L     A  +   ++       +  + + +   ++R   D  +     A    +    
Sbjct: 58  IKLR-SPEAYHKEVVIRGFGEEIKVRSDEEFAVATLDRRKLDKELLDEAIAQGAEFRKEK 116

Query: 123 CRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFA 182
              +  ++D+  VI          ++RY++GADGA S+        +  R    I     
Sbjct: 117 VSGVISKEDRVEVIGSG------FSSRYVIGADGAYSITAISSGIRNCWRNDDIIFA-IE 169

Query: 183 EKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFG 242
            + P+        ++  + Y W   +      G        +      +E    ++ +  
Sbjct: 170 GRAPLYDELTFIVDASPSGYGWIFPRGEDSNAGVGGISSKSREVIKAFEEFSKRYKVEKV 229

Query: 243 KTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLK 302
                     + P+   D    K    L+G+AAG     + EG+ YA  S       L  
Sbjct: 230 GNW-------IIPTGGHDKQIAKGRVLLVGDAAGLADPLTGEGLYYAFKSALECSKSL-- 280

Query: 303 QPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPAL 337
           + E    +Y        ++      K+R +  P +
Sbjct: 281 ESEDPALSYSENM-GNVMEELRLKRKARNIIVPRM 314


>UniRef50_A6BZI3 Probable alkylhalidase n=1 Tax=Planctomyces maris DSM 8797
           RepID=A6BZI3_9PLAN
          Length = 430

 Score =  204 bits (520), Expect = 3e-51,   Method: Composition-based stats.
 Identities = 59/338 (17%), Positives = 110/338 (32%), Gaps = 31/338 (9%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
            +DV IIG GPAGS +A  LA + +   +  + +          G  L P+      R G
Sbjct: 15  EYDVVIIGAGPAGSTVAALLAEQGRNTLVVDRARFPRFHV----GESLIPETYWPLKRLG 70

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNY---------QRSYININRHAFDLWMKSLIP- 112
           L   +   A P+  SV+ V      T  +               + R  FD  +      
Sbjct: 71  LIERLKQTAFPKKLSVQFVTDEGVETMPFYFHDYKDHESSQTWQVYRAEFDQMLIDNAQS 130

Query: 113 ASVEVYHDSLCRKIWREDDKWHVIFRADGWEQH--ITARYLVGADGANSMVRRHLYPD-- 168
                ++++    +  +D++   +    G ++   ITAR +V A G +  +   L     
Sbjct: 131 KGATFHNEAQVTDLLTQDEQVTGVKVKLGNQETRNITARLVVDASGQSGFIANRLKLKQT 190

Query: 169 HQIRKYVAIQQWFAEKHPVPF----YSCIFDNSITNCYSWSISK-DGYFIFGGAYP---- 219
             + +   +   F      P      + I        + W I   D     G        
Sbjct: 191 DPVLRKGTVWAHFKNAQRDPGIDEGATLILQTEGKRSWFWYIPLQDNVVSIGCTGDMNYM 250

Query: 220 ----MKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAA 275
                K+ +  F    E+    + +  +     +        +           L G+A 
Sbjct: 251 FSKERKNSEDIFFQEVERCIGIKRRLTEAHPVTEFMTTKDFSYHSSQPAGPGWMLAGDAL 310

Query: 276 GFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWR 313
           GFI      G+  A+ S +++   + +  E  + +  R
Sbjct: 311 GFIDPVYSSGVFLAMKSGELIADAINEAYETDDFSVER 348


>UniRef50_Q4JN54 Putative uncharacterized protein n=1 Tax=uncultured bacterium
           BAC13K9BAC RepID=Q4JN54_9BACT
          Length = 369

 Score =  203 bits (518), Expect = 7e-51,   Method: Composition-based stats.
 Identities = 63/338 (18%), Positives = 112/338 (33%), Gaps = 17/338 (5%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQ-VIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           ++  D+ I+G GP+G   A  L    + V  LDK          KPC G L P       
Sbjct: 5   IKETDILIVGAGPSGCMAASILKDSGRNVTLLDKND----FPRHKPCAGGLTPKTVDEL- 59

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYH 119
                +      + +    K  +       N   +   + R  FD +  + +        
Sbjct: 60  --PFEIADLKQHDSEKMLFKFTNGKTVDLNNESGACKMVVREEFDNFFLNYVKNKGTELM 117

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQ 179
                 I+   ++  V       +  I  ++L+GADGANS VRR            A + 
Sbjct: 118 KGKVTAIYDAPNEVVVET----SDYKIKCKFLIGADGANSTVRRLTTDLEFKNPVFAFEG 173

Query: 180 WFAEKHPVPFYSC-IFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQ 238
               K            N +   Y W   K  ++  G    + D         +  S  +
Sbjct: 174 LVDRKISAKDVPTKFVFNEL--GYGWIFPKKEHYNVGIGNLVFDPTQPKPKKNDLFSFVK 231

Query: 239 FQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRS 298
            + G    +        +   ++    +  +LIG+AAG       EGI  A+ S   + +
Sbjct: 232 DELGTNEVTHITGFPIGTEGNEYFPTSERIYLIGDAAGLAETLLGEGIYNAVISGKYIAN 291

Query: 299 VLLK--QPEKLNTAYWRATRKLRLKLFGKIVKSRCLTA 334
            ++    P+ +   Y +    ++ +L      S+ L  
Sbjct: 292 SIVGTNNPKDVYKKYLKFLVGMKKELALYNKASKILYK 329


>UniRef50_D2QMD3 Monooxygenase FAD-binding protein n=5 Tax=Bacteroidetes
           RepID=D2QMD3_9SPHI
          Length = 375

 Score =  203 bits (517), Expect = 9e-51,   Method: Composition-based stats.
 Identities = 59/368 (16%), Positives = 130/368 (35%), Gaps = 33/368 (8%)

Query: 5   DVAIIGLGPAGSALARKLAGK-MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           DV IIG G AG   +  L    +QV+ L+K+         K CG  ++ +        G+
Sbjct: 6   DVIIIGGGLAGLTASIHLTRADVQVLLLEKQD----YPQHKVCGEYISNEVLPYLQHLGV 61

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLC 123
            +  ++  +     + +     ++          ++R+  D ++     ++      +  
Sbjct: 62  DID-ELNPSRISRFLLSTAAGKTVESTLPLGGFGVSRYTLDQFLADKAKSAGVDLRQADV 120

Query: 124 RKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDH--QIRKYVAIQQWF 181
             I   ++ + V       EQ  TA+ ++GA G  S + + L      +   ++ ++  +
Sbjct: 121 TDIQFANNVFTVTTAT---EQTYTAKIVLGAYGKRSQLDKRLNRPFASRESGWLGVKAHY 177

Query: 182 AEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRF------TTLKEKMS 235
             +   P       N        S  ++G          +  +           +  K  
Sbjct: 178 --QADFPDDLVALHNFDGGYCGLSQVENGIVNACYLVNYRSFKAVKNIDSFQQHVLRKNP 235

Query: 236 AFQFQFGKTVKSEKCTVLFP-SRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTD 294
                F          +      +      +++  + G+ AG I      G++ A+ S  
Sbjct: 236 FLNEFFATATPLFARPLTISQISFDKKSPVENHILMCGDTAGLIHPLCGNGMAMAIHSAK 295

Query: 295 ILRSVLLK----------QPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRS 344
           ++  ++++            EK  T+ W A  + RL L G+I ++  L  PA+   I++S
Sbjct: 296 LVSELVIQFFNGKLANRAALEKQYTSGWSAEFRTRL-LTGRIAQTVLLY-PAITNVILKS 353

Query: 345 GVAHIPQL 352
            +   P +
Sbjct: 354 -LQRTPGI 360


>UniRef50_A1U6D3 Geranylgeranyl reductase n=2 Tax=Marinobacter RepID=A1U6D3_MARAV
          Length = 374

 Score =  203 bits (516), Expect = 1e-50,   Method: Composition-based stats.
 Identities = 68/336 (20%), Positives = 107/336 (31%), Gaps = 23/336 (6%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           ME++D+ I+G GPAGS LAR L    + + +  K         K C G + P    S   
Sbjct: 1   MEYYDIIIVGAGPAGSTLARALEDSGKRVLIIDKQ---AFPRDKTCAGWVTPAVMASLDI 57

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQR-SYININRHAFDLWMKSLIPASVEVYH 119
           D     V     P       +   +++  ++       I R  FD ++        E   
Sbjct: 58  DPGKYSVGRTLQPIRRFRIGMMGQSAVENDHGDIVSYGIRRCEFDDYLLDRAEC--EKQL 115

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYP-DHQIRKYVAIQ 178
            +  + I R +  W +            A  LVGA G    V R L     +    VA +
Sbjct: 116 ATAVKSINRNNGNWVI-------NDQWQAPLLVGAGGHFCPVARLLGDGPGKHETVVAAK 168

Query: 179 QWFAEKHPVPFYSCIFDNSITN--------CYSWSISKDGYFIFGGA-YPMKDGQTRFTT 229
           +   E  P    +C                 Y+W   K  Y   G               
Sbjct: 169 EVEFEMTPEQARACEARGDTPELWFCRDLKGYAWVFRKGSYLNIGLGREDNHRLSDHLEA 228

Query: 230 LKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYA 289
             E+M              K          +     D   LIG+AAG     S EGI  A
Sbjct: 229 FVEEMKQSGRIPSDLPGRFKGHAYLLYAHANRPLVDDGVLLIGDAAGLAYTQSGEGIRPA 288

Query: 290 LDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGK 325
           ++S  +  +V+   P+    +      ++  +   +
Sbjct: 289 IESALMAANVIKAAPDYSALSLQSYGERIAERFGTR 324


>UniRef50_D1YYN0 Geranylgeranyl reductase n=1 Tax=Methanocella paludicola SANAE
           RepID=D1YYN0_METPS
          Length = 389

 Score =  202 bits (515), Expect = 1e-50,   Method: Composition-based stats.
 Identities = 62/344 (18%), Positives = 106/344 (30%), Gaps = 26/344 (7%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
            ++DV ++G GPAGS  A   A   + V+ ++K+ + G       C   +       FI 
Sbjct: 3   NNYDVIVVGAGPAGSVAATTAARKGLDVLLIEKRQEIGVPVR---CAEGVIKAGLDEFIE 59

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKS-LIPASVEVYH 119
                P  V A  +   +   D           +   ++R  FD  +      A  EV  
Sbjct: 60  Y---DPKWVCAEVRRGRIHAPDGNMLCFSQEDTAGYILDRKIFDRSLAKTAAHAGSEVQV 116

Query: 120 DSLCRKIWREDDKW-HVIFRADGWEQHITARYLVGADGANSMVRRH---LYPDHQIRKYV 175
            +    +  ED     +  +  G E    A+ ++GADG  S + R    L P        
Sbjct: 117 KTQATGLIIEDGCVKGITGKCRGQEFEARAKVIIGADGVESKIGRQAGLLGPLRLKDVES 176

Query: 176 AIQQWFAEKHPVPFYSCIFDNS--ITNCYSWSISKD-GYFIFGGA--YPMKDGQTRFTTL 230
             +   +     P    ++  +      Y W   K       G A      +G      L
Sbjct: 177 CAEFLVSGIDIDPDCLELYFGNKLSPGGYLWVFPKGKNEANIGVANLADRLNGAHPIDYL 236

Query: 231 KEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYAL 290
           +  +S   F  GK ++     V   +             L G+ A  +      GI  A+
Sbjct: 237 ERYVSEH-FPDGKIIQVVSGAVPVCNLPGRLSMS--GLLLAGDGARLVDPLLGAGIMNAM 293

Query: 291 DSTDILRSVLLKQPEK------LNTAYWRATRKLRLKLFGKIVK 328
            S  +  ++                 Y    R    K   +  +
Sbjct: 294 ISGRMAGNIAANAINAGDVSAKALKTYDHEIRSTIGKAIRRNYR 337


>UniRef50_UPI000038E1B1 geranylgeranyl hydrogenase n=1 Tax=Ferroplasma acidarmanus fer1
           RepID=UPI000038E1B1
          Length = 393

 Score =  200 bits (510), Expect = 5e-50,   Method: Composition-based stats.
 Identities = 58/330 (17%), Positives = 110/330 (33%), Gaps = 28/330 (8%)

Query: 4   FDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +DV + G GP+GS L+  L+    +V+ L++  + G       C GL++    +      
Sbjct: 15  YDVIVSGAGPSGSYLSYLLSRNGYKVLQLEEHREVG---KPVECTGLVSERVFKYVNS-- 69

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVYHDS 121
                  + N    +        S+  +     I + R  FD  +    I A  +   ++
Sbjct: 70  -----RSMVNEVHGANVFFPNGKSIHISKGEKTIVMYRDDFDKDVSAMAIGAGADTRINA 124

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW- 180
                   D    V +R +G  ++  A  +VGADGANS +R  L  +   +     Q   
Sbjct: 125 RVLDAKVNDSYGEVKYRENGEIKYARANIIVGADGANSRIRLSLNYERPKKIISTYQVDS 184

Query: 181 -FAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQF 239
            F           I   +    + W++        G             T  +       
Sbjct: 185 SFHLDDQDDVNVFIGSENSKGFFGWAVPSGEITRIGVGVDH-------VTAIKYFRNINV 237

Query: 240 QFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSV 299
           +F ++          P  +       + + L+G+AAG +   S  GI   + S     + 
Sbjct: 238 KFNRSQILGINAGPIPINYLSKTY-GNRSLLLGDAAGIVKPLSGGGIYTGIISAKNAYTA 296

Query: 300 LLKQ------PEKLNTAYWRATRKLRLKLF 323
           + +        E    AY +  ++   +  
Sbjct: 297 IDQSFNRNNFSEDALKAYQKLWKREIGREL 326


>UniRef50_A1RY40 Geranylgeranyl reductase n=1 Tax=Thermofilum pendens Hrk 5
           RepID=A1RY40_THEPD
          Length = 387

 Score =  200 bits (510), Expect = 5e-50,   Method: Composition-based stats.
 Identities = 71/347 (20%), Positives = 119/347 (34%), Gaps = 21/347 (6%)

Query: 3   HFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            +D A++G GPAG   AR LA    +V  L+K          KPCG  ++    ++   +
Sbjct: 2   QYDAAVVGAGPAGLMFARVLASKGFRVAVLEKNETLAV----KPCGEGISARVLQTAEIN 57

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKS-LIPASVEVYHD 120
                  V    +   V   +    + +        I++  F   M         ++Y  
Sbjct: 58  RSDTQRFVSHAIKGAVVVAPNGRKVVIKEEGELGYVIDKRNFLRVMGEYAASYGADIYMK 117

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYV----- 175
              +++  ++  W V  R       + AR LVGADG  S   + L  +    + V     
Sbjct: 118 EPVKEVVFKNGHWTVRART----VELEARLLVGADGYLSYTAKALGLEKPGERRVIPTVQ 173

Query: 176 AIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYF-IFGGAYPMKDGQTRFTTLKEKM 234
            +      + P   Y  + +      Y W   KDG     G       G +    L + +
Sbjct: 174 YVMPNVELEDPDMTYFFLGNEVAPKGYVWIFPKDGRLANVGIGV---QGASPKAYLDKFI 230

Query: 235 SAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTD 294
                 FGK    E                 ++A L+GEAAG +   +  GI  ++    
Sbjct: 231 KNNPSIFGKARILEFRGAAVTIGGMLSEIVSEHAMLVGEAAGQVIPLTGGGIHTSIAGGK 290

Query: 295 ILRSVLLKQPE--KLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRK 339
           I   V  K      L+       +KL  + +GK ++       A+ K
Sbjct: 291 IAAEVASKALAEGDLSKKRLEEYKKLYNEYWGKRIRDSLKGLHAIEK 337


>UniRef50_D1CDE0 Geranylgeranyl reductase n=1 Tax=Thermobaculum terrenum ATCC
           BAA-798 RepID=D1CDE0_THET1
          Length = 398

 Score =  200 bits (510), Expect = 6e-50,   Method: Composition-based stats.
 Identities = 63/343 (18%), Positives = 119/343 (34%), Gaps = 24/343 (6%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           +E  +V I+G GPAGS++A  LA     V+ LDK          KPC   ++P       
Sbjct: 2   IEEREVVIVGGGPAGSSVANVLASLGHDVLLLDKS----RFPRPKPCSEYMSPGILPLLS 57

Query: 60  RDGLTLPV---DVIANPQIFSVKTVDVAASLTRNYQRSYI--NINRHAFDLWMK-SLIPA 113
             G+   +    ++   +I +     +       +   Y    + RH FD  +       
Sbjct: 58  NLGIDADLSGMHMLKGMRIHTPAGSQITIEYVDEHNGRYYAPTMERHVFDKMLLDHAAHK 117

Query: 114 SVEVYHDSLCRKIWREDDKWHVIFRADGWEQ-HITARYLVGADGANSMVRRHLYPDHQI- 171
            VEV + +    +  +D+   +  +     Q  I  + ++GADG  S+V R+L   + + 
Sbjct: 118 GVEVRYQAKVMSVVSQDNYSILRVQLPDRAQMDIRTKLVIGADGLRSVVARNLSRRYPLI 177

Query: 172 -RKYVAIQQWFAEKHPVPFYSCIFDNSITNCY-SWSISKDGYFIFGGAYPMKD------G 223
             K + +            Y  ++ +     Y   + +       G    ++        
Sbjct: 178 WPKRMGLVTHINLPGIDADYGDMYVH--PWGYCGVAATGKSSASVGIVLDLRRMALTRGR 235

Query: 224 QTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSL 283
           +  F    +       Q       ++   + P           N  L+G+AAGF    + 
Sbjct: 236 EAIFEDSLKLFPKAHKQICGAASFDRIMGISPIGHGVKEVHGRNWALVGDAAGFFDPFTG 295

Query: 284 EGISYALDSTDILRSVLLKQPEKLN-TAYWRATRKLRLKLFGK 325
           EGI  A+    +L  V+    +              R ++F +
Sbjct: 296 EGIYKAVRGGILLGEVVSPYLKVGRIKEGLERYATERARVFRR 338


>UniRef50_C0ZA99 Electron transfer flavoprotein-quinone oxidoreductase n=4
           Tax=Firmicutes RepID=C0ZA99_BREBN
          Length = 431

 Score =  200 bits (510), Expect = 6e-50,   Method: Composition-based stats.
 Identities = 60/341 (17%), Positives = 109/341 (31%), Gaps = 35/341 (10%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           E FDV I+G GPAG+A A  LA     V+ +++    G++      GG+L        I 
Sbjct: 3   EKFDVIIVGAGPAGTACAYTLAKAGVNVLLMERGEYPGSKN---VMGGVLYRKTMEDIIP 59

Query: 61  DGL-TLPVDVIANPQIFSVK------TVDVAASLTRNYQRSYININRHAFDLWMKSLIPA 113
           +     PV+     Q F +                     +   + R  FD W       
Sbjct: 60  EFYKEAPVERPIVEQRFMMLDRESAINFSYKGMEWAQEPYNNFTVLRAKFDQWFADKAVQ 119

Query: 114 SVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRK 173
              +  +         ++   V  + D  +  + A  +V ADG NS++ + L    + R 
Sbjct: 120 QGALLLNETVALQCIVENGKVVGVKTDRPDGDLYADVVVLADGVNSLLAKSLGFHKEFRP 179

Query: 174 ---YVAIQQ-----------WFAEKHPVPFYSCIFDNSITN--CYSWSISKDGYFIFGGA 217
               +A+ +            F  +        IF +S       +W  +       G  
Sbjct: 180 DEVALAVMEVLKLDRKIIEDRFNLEGDHGCTIEIFGDSTKGILGTAWLYTNKDSLNIGVG 239

Query: 218 YPMKDGQTRFTTLKEKMSAFQFQFG------KTVKSEKCTVLFPSRWQD--FVCGKDNAF 269
             +           E +   +             + E    L P            +   
Sbjct: 240 TMLSGLIKNKIKPYELLDYVKNHPMIRPYIQGCEQQEYLAHLIPEGGYRSIPKIVGNGVL 299

Query: 270 LIGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKLNTA 310
           ++G+AA  ++A   EG + A+ S  +    +L   E  + +
Sbjct: 300 VVGDAAQLVNAIHREGSNMAMASGVMAAETILAAKEAGDYS 340


>UniRef50_Q3A1Y0 Flavoprotein-containing dehydrogenase n=1 Tax=Pelobacter
           carbinolicus DSM 2380 RepID=Q3A1Y0_PELCD
          Length = 414

 Score =  199 bits (508), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 77/370 (20%), Positives = 122/370 (32%), Gaps = 23/370 (6%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           ++ +DV I G GPAGS  A  LA     + L  +        SK CG  L P A R   R
Sbjct: 25  VQTWDVIIAGAGPAGSIAAITLADMGHRVLLTDRDW---FPRSKVCGDCLTPGAMRILRR 81

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVYH 119
            GL     + A  +   ++ +   A +  +    Y+ + R   D  + +  + A V    
Sbjct: 82  YGL-FDAALHAGHRCTQMR-IYSPAHVRIDVPGDYLTVKREILDQLLARKALAAGVTFVR 139

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYP-DHQIRKYVAIQ 178
            +      R D +  V FR     Q      L  A G    + +      H +    A++
Sbjct: 140 GTAAALEKRGDAEIAVRFREGPSMQVARCGLL--ATGGRLALAQKSGLVAHPVASGAAVR 197

Query: 179 QWFAEKHPVPFYSCIFDNSITNCYSWSISKD-GYFIFGGAYPMKDGQTRFTTLKEKMSAF 237
            +   + P+       + +I   Y+W    +   +  G    M         LK    AF
Sbjct: 198 CYVRSRLPIKHMVIACERTILPGYAWIFPVEKDLYNVGCGRFMYRQTEPHLHLKRSFHAF 257

Query: 238 QFQF---------GKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISY 288
              F         G      K  VL                 +GE  G  S  + EGI  
Sbjct: 258 LHTFPIARELMEQGDMETPLKGAVLRSGWQHIGPMASGACLGMGEMVGTTSPYTGEGIGK 317

Query: 289 ALDSTDILRSVLLKQPEKLN----TAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRS 344
           A+ S  +   ++ +   K +      Y    R LR   +    ++R      L    +  
Sbjct: 318 AMQSGVLAAKLVHRCLRKGDMSELLRYPGYLRLLRGMCYDGFERTRKWFEHPLLVDFLAH 377

Query: 345 GVAHIPQLKD 354
            + H P L D
Sbjct: 378 RINHSPYLYD 387


>UniRef50_C3XVJ7 Putative uncharacterized protein n=1 Tax=Branchiostoma floridae
           RepID=C3XVJ7_BRAFL
          Length = 485

 Score =  199 bits (506), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 66/374 (17%), Positives = 119/374 (31%), Gaps = 26/374 (6%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           +DVA++G GPAGS L   LA   +   L +K +       K CG  +   A    +  G+
Sbjct: 63  YDVAVVGAGPAGSTLGYYLAKAGRNCLLLEKKK---FPRDKYCGDAVCKTAIEILMDMGI 119

Query: 64  --TLPVDVIANPQIFSVKTVDVAASLTRNYQ------RSYININRHAFDLWMKSLI-PAS 114
              L  +  A              S     +       + +   R   D  +      A 
Sbjct: 120 YEKLIKENKARIADAGGLCSPGGLSYIGRSKEILGEVPAALACKRWWLDEAIAMAAKRAG 179

Query: 115 VEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKY 174
             +  +S  R    +          +  ++   AR LV ADGA S +   L    +    
Sbjct: 180 AHLMENSGVRDAVFDAKAGLWTVYLEDSDKSYKARILVCADGAPSKLATKLGIVKRPPDG 239

Query: 175 VAIQQWFA-EKHPVPFYSCIFDNSI-TNCYSWSISK-DGYFIFGGAYPMKDGQTRFTTLK 231
              + +     H      CIF +      YS      +    +       + +     L 
Sbjct: 240 SCSRAYVESGTHKFKADGCIFYHRDMLPGYSALFRHPNNELNYCVYLIPGNPKVTNDDLP 299

Query: 232 EKMSAF-------QFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLE 284
              +             G   K E+          + V   D+  ++G+AAG I   + E
Sbjct: 300 YWHNFLMKQDPNISKSLGPGAKLERMKAASLRLGGEPVSHGDHVLVVGDAAGMIDPMTGE 359

Query: 285 GISYALDSTDILRSVLLKQPEKL--NTAYWRATRKLRLKLFGKIVKSRCLTAPALRKW-- 340
           GI +A+++  +    L +       +    +   +  +  FG   K        L ++  
Sbjct: 360 GIHHAMEAGKMAAKFLDEAMHHGNYDKDVMKLYHEAWMDKFGSDFKWSFAICQLLYRFPI 419

Query: 341 IMRSGVAHIPQLKD 354
           ++ +  A I +  D
Sbjct: 420 LLDAATAAIARKGD 433


>UniRef50_A8UYA2 Putative uncharacterized protein n=2 Tax=Aquificaceae
           RepID=A8UYA2_9AQUI
          Length = 345

 Score =  198 bits (505), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 61/323 (18%), Positives = 105/323 (32%), Gaps = 18/323 (5%)

Query: 3   HFDVAIIGLGPAGSALARKLAGK-MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            +DV I+G GPAG+  A  L+   ++V+ +D K   G       C   +    +  F   
Sbjct: 2   KYDVLIVGSGPAGATAAYILSRNDVRVLLVDIKRAPG---VPVQCAEFVPIQLKHKFPEF 58

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDS 121
               P DV+A      V        ++   Q     ++R  FD  +              
Sbjct: 59  F---PKDVVAQEVRDMVHFTPWGEVVSM--QSEGYVLHRDRFDRGIVERALKGGTELRLR 113

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWF 181
               +  ED K  +          + A  ++GADG  S V R    +H        Q  F
Sbjct: 114 TVF-LGFEDGKVWLEHIDTRKRYAVEAELVIGADGPRSRVARLTG-EHTGSFLATAQFTF 171

Query: 182 AEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQF 241
             +  V      F + I   Y W   K      G             +L+  ++    + 
Sbjct: 172 PLRERVSDLLIYFRDYIPGGYGWVFPKGELANVGVGIDPHYPVNVMESLRRLVAELTSEG 231

Query: 242 GKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLL 301
               +    T  +          + N  L+G+A GF    +  GI+ A+ +  +    +L
Sbjct: 232 VVGKEVLGRTGGWIPAEGVKRPLRGNVVLVGDAGGFCHPITGGGIANAVYTGAMAGEAIL 291

Query: 302 KQPEKLNTAYWRATRKLRLKLFG 324
           +              +  ++LFG
Sbjct: 292 EGD-------LEDYSEESMELFG 307


>UniRef50_A3HTX2 FAD dependent oxidoreductase, putative n=1 Tax=Algoriphagus sp. PR1
           RepID=A3HTX2_9SPHI
          Length = 370

 Score =  198 bits (505), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 50/346 (14%), Positives = 122/346 (35%), Gaps = 21/346 (6%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           M+ ++V I+G G AG   +  LA   + + L +K       F + CG  ++ +     +R
Sbjct: 1   MDKYEVIIVGGGLAGLVASFLLAKGGKKVLLIEKK---NYPFHRVCGEYVSNEVYEFLMR 57

Query: 61  DGLTLPVDVIANPQIFSVKTVD-VAASLTRNYQRSYININRHAFDLWMKSLIPA-SVEVY 118
           + L     V   P++      D    +           I+R   D ++   +        
Sbjct: 58  EELLP--TVYDLPRMTHFLFSDTSGNTAKVPLGLGGFGISRFVLDAYLFQRVKEMGASSQ 115

Query: 119 HDSLCRKIWRE--DDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVA 176
             +   K+  +  ++++HV  R     +   A Y++GA G  S + + L      ++   
Sbjct: 116 TGATVEKLTFDTSENQFHVGLRTG---EEYRADYVIGAFGKRSKLDKTLQRPFIEKRSPY 172

Query: 177 IQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQT--RFTTLKEKM 234
           I   +  K      + +  N        +  ++G          +  +       +++++
Sbjct: 173 IGVKYHIKTEFDSSAVVLHNFEGGYCGLNAIEEGKGNLCYLGKREALRHFGSLEAMEKEV 232

Query: 235 SAFQFQFGKTVKSEKCTVLFPSR-----WQDFVCGKDNAFLIGEAAGFISASSLEGISYA 289
                   K     +  +  P       ++     +++  + G++AG I+     G++ A
Sbjct: 233 LWKNPHLKKLFTESEFLLEKPEVINEINFEKKQPVENHILMAGDSAGLITPLCGNGMAMA 292

Query: 290 LDSTDILRSVLLK--QPEKLNTAYWRATRKLRLKLFGKIVKSRCLT 333
           + S  +    +L+    E +  +Y +  +    +       ++ L 
Sbjct: 293 IHSGKLAAEAILEGKSREGVEKSYEKVWKSKFERRLWVGRNTQRLF 338


>UniRef50_P26172 Geranylgeranyl diphosphate reductase n=34 Tax=Bacteria
           RepID=BCHP_RHOCA
          Length = 391

 Score =  198 bits (504), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 77/342 (22%), Positives = 123/342 (35%), Gaps = 27/342 (7%)

Query: 3   HFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            +D  ++G GPAGS  A  +A   ++V  LD+       G  KPCGG + P   R F   
Sbjct: 2   KYDAFVVGGGPAGSTAAWDMARAGLKVALLDRA------GRIKPCGGAIPPRLIRDFD-- 53

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYI-NINRHAFDLWMKSLIPASVEVYHD 120
              +P  ++      +         +    +  ++  ++R  +D W++     +      
Sbjct: 54  ---IPDHLLVAKITSARMISPTGRFVDIPIENGFVGMVDREDYDEWLRERAGKAGAERLT 110

Query: 121 SLCRKIWREDDKWHVIFRA--DGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQ 178
               +I R+  K  V++R    G E     R ++GADGANS VR  + P  +I    A  
Sbjct: 111 GTWLRIERDSGKTVVVWRDKVTGEEMKAETRVVIGADGANSQVRNEV-PATKIPLVFAYH 169

Query: 179 QWFAEKH-----PVPFYSCIFDNSI-TNCYSWSISKDGYFIFGGAYPMKDGQ-TRFTTLK 231
           +                   +D  I  + Y W          G    + D      TTL 
Sbjct: 170 EIIKAPTTVANYDPTRCDVYYDGRISPDFYGWVFPHGKTASIGMGTELPDVSLKDCTTLL 229

Query: 232 EKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALD 291
            +MS       K     K     P +  D      +  L G+AAG ++ SS EGI YA  
Sbjct: 230 RQMSGL----DKEETIRKEGAPIPLQPLDVWDNGKDVVLSGDAAGVVAPSSGEGIYYAHA 285

Query: 292 STDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLT 333
                    +   +    A  +  R   +K  G + K   + 
Sbjct: 286 GGRYAAEAAMAFLKSGKPADLKLARAGFMKEHGTVFKVLRMM 327


>UniRef50_B8G4M6 Geranylgeranyl reductase n=6 Tax=Chloroflexaceae RepID=B8G4M6_CHLAD
          Length = 421

 Score =  198 bits (504), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 61/333 (18%), Positives = 106/333 (31%), Gaps = 17/333 (5%)

Query: 6   VAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTL 65
           V I+G    G+  A  L        L +K         KPCGG + P A R F     +L
Sbjct: 5   VLIVGASVGGATAAITLRSFGIETILIEKELVKA----KPCGGAVPPAAFREFD-LPTSL 59

Query: 66  PVDVIANPQIFSVKTVDVAASLTRNYQ---RSYININRHAFDLWMKSLIPASVEVYHDSL 122
               +    I S    +    +             + R  FD +++            + 
Sbjct: 60  IDRKVRQCLIVSPSGQETRVPVAGTVPSEDDYVAMVRREVFDSFLRRRAQERGAELIHAQ 119

Query: 123 CRKIWREDDKWHVIFRA-DGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWF 181
              +  +       +R   G E  + A  ++GADGA S   + L   + + + VA+Q+  
Sbjct: 120 LIGLRVDRRGVEATYRTPSGHEGSVWADVVIGADGAYSPTAKFLGLPN-LPRAVAMQERI 178

Query: 182 AEKHP------VPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMS 235
                            +      + Y+W+  K  +   G     + G      L     
Sbjct: 179 KLPPDKMARWEETADLYLGHEVSPDLYAWAFPKRDHIAVGIGAGPRHGSAAKQLLNNLKR 238

Query: 236 AFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDI 295
                        +     P          D    IG+AAG +  +S EGI +A+ S  +
Sbjct: 239 RLGSALDGGQVILREAHALPME-PRPHLAFDRVMFIGDAAGLVVHTSGEGIYWAMKSGQM 297

Query: 296 LRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVK 328
               L +  +  + A  R   +   K +G + +
Sbjct: 298 AAQTLAEYLDAPSEANLRTYERRWWKQYGTMYR 330


>UniRef50_B1L6M6 Geranylgeranyl reductase n=1 Tax=Candidatus Korarchaeum cryptofilum
           OPF8 RepID=B1L6M6_KORCO
          Length = 380

 Score =  198 bits (504), Expect = 3e-49,   Method: Composition-based stats.
 Identities = 66/341 (19%), Positives = 114/341 (33%), Gaps = 25/341 (7%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           ME +DV ++G GPAG + A+  A   ++VI L+           KPCG   +      F 
Sbjct: 1   MEEWDVIVVGGGPAGLSAAKFSAELGLKVILLEAYSDIRA---WKPCGEGTSKTT---FE 54

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLI-PASVEVY 118
             G+     V++N     V                   IN+  F L +      A  E+ 
Sbjct: 55  TAGIEPKPGVVSNELSMKVYAPSGKYVEI---PLHGYAINKDLFLLELAKKAYLAGAEIR 111

Query: 119 HDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQ 178
                  + +E+ +   +  A G    +  + +VGADG NS V +    D++       Q
Sbjct: 112 VGERVESVLKENGRVCGVKTAKGE--TLRGKVVVGADGYNSTVAKSSGLDNRTELIPTYQ 169

Query: 179 QWFAEKHPVPFYSC-IFDNS-ITNCYSWSISKDGYF-IFGGAYPMKDGQTRFTTLKEKMS 235
                     + S  I+  S     Y+W   KD      G        +     L + + 
Sbjct: 170 YKMVGVELDSYNSGRIYVGSMAPGGYAWIFPKDDQVANVGIGVRPGSPKLY---LDKFIK 226

Query: 236 AFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDI 295
                F K         + P          D   LIG+AAG +   +  GI  ++ +   
Sbjct: 227 ERPEIFRKAKIIGVGGYVVPIGGLAREYIGDGVILIGDAAGMVIPFTGAGIHSSIAAGKA 286

Query: 296 LRSVLLKQPE------KLNTAYWRATRKLRLKLFGKIVKSR 330
           +   + +  E         +++ R       ++   +   R
Sbjct: 287 VSRTIAEALEKGDTSKGALSSFEREYEGWIKRIRDSLRAMR 327


>UniRef50_Q0W1J4 Predicted FAD-dependent oxidoreductase n=2 Tax=Euryarchaeota
           RepID=Q0W1J4_UNCMA
          Length = 394

 Score =  198 bits (503), Expect = 3e-49,   Method: Composition-based stats.
 Identities = 65/349 (18%), Positives = 110/349 (31%), Gaps = 19/349 (5%)

Query: 3   HFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            +DV ++G GPAGS  A+  A    + + L++  Q G+      C GL++ +A       
Sbjct: 2   DYDVIVVGAGPAGSMAAKYAALNGAKTLLLEEHGQVGS---PVACTGLISRNALDECELG 58

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLI-PASVEVYHD 120
             +     I    + S         L    +     + R   D  M      A  E+   
Sbjct: 59  EGSFINKRIRGAFVHSPNN---HNILLDGKRTMAYVVERKIMDREMARRAVNAGAEILIS 115

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW 180
           +    I        V        + ITA  ++GADG  S V R     +      AIQ  
Sbjct: 116 TKAEGITPVPGGISVKVTGPDGTEDITASVVIGADGVKSKVARAAGLGNLPHVCSAIQVE 175

Query: 181 FAEKHPVPFYSCIFDNS--ITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQ 238
              +   P +  +F  S      ++W++   G     G    +        L  +     
Sbjct: 176 ATYEPRNPDFVEMFSGSRYAPKHFAWAVPTSGDCCRVGLISDEHAHEYLQRLLTEHEIVS 235

Query: 239 FQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRS 298
            +    V      V             DN  ++G+AAG +   S  GI        I   
Sbjct: 236 KKARSAVDLIMGGVPV---GTLKRTVTDNIMIVGDAAGQVKPISYGGIYTGARCARIAGE 292

Query: 299 VLLKQPEKLNTA------YWRATRKLRLKLFGKIVKSRCLTAPALRKWI 341
           V  K     + +      Y R  R    +    +++ R +      + +
Sbjct: 293 VAAKAALAGDASSARLMEYERRWRADIGRELMMMMRFRQMYGRMTDQDL 341


>UniRef50_B3QZ41 Geranylgeranyl reductase n=12 Tax=Chlorobiaceae RepID=B3QZ41_CHLT3
          Length = 383

 Score =  198 bits (503), Expect = 3e-49,   Method: Composition-based stats.
 Identities = 60/322 (18%), Positives = 118/322 (36%), Gaps = 23/322 (7%)

Query: 25  KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTVDVA 84
            +  + +++         +KPCGG +       F      +P +++              
Sbjct: 25  GISNVLIER-----NFNNTKPCGGAIPLGLIEEFA-----IPDEIVERKVDHMAVRSPKG 74

Query: 85  ASLTRNYQRSYI-NINRHAFDLWMKSLIPASVEVYHDSLCRKIWREDDKWHVIF-RADGW 142
             +  +    ++  + R  FD +++    A      ++  RK+ + +  + +    A   
Sbjct: 75  RVIEMHMPTGFVGMVRRERFDRFLRERAAADGTELLEAKMRKVRKTNGVYQISVDAASKG 134

Query: 143 EQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEKHPVPFY----SCIFDNSI 198
              I A+Y++GADGANS V   L       K +AIQ+ F     +  Y       FD  +
Sbjct: 135 VSEIEAKYVIGADGANSKVANELGFPPNEYKAIAIQERFHYSPALERYNNLVEIWFDGEV 194

Query: 199 -TNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSR 257
             + Y W   K  +   G     K G      +++  + F+ + G  ++           
Sbjct: 195 SPDFYGWIFPKADHVAIGTGTDDKHG-----NIRKLQARFREKIGLDIEPYLEEAAKLPM 249

Query: 258 WQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRK 317
                  +++A L+G+AAG ++ S+ EGI +A+ S  +    L         +   A   
Sbjct: 250 HPRKSFTQESAMLVGDAAGLVTPSNGEGIFFAMRSGKMAGQTLANFINGQEKS-LHAYEA 308

Query: 318 LRLKLFGKIVKSRCLTAPALRK 339
              KL+  I K   +      +
Sbjct: 309 NFHKLYKIIFKGLGMMQSVYYR 330


>UniRef50_D1UBL8 Geranylgeranyl reductase n=1 Tax=Desulfovibrio aespoeensis Aspo-2
           RepID=D1UBL8_9DELT
          Length = 405

 Score =  197 bits (502), Expect = 4e-49,   Method: Composition-based stats.
 Identities = 70/376 (18%), Positives = 126/376 (33%), Gaps = 32/376 (8%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M  +DV ++G GPAG+  A   A   + V+ LD+K         K CG  L+  A     
Sbjct: 1   MSDYDVIVVGAGPAGTCTAIHAARQGLHVLLLDQKK----FPREKTCGDALSSLAIAELN 56

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAAS--------LTRNYQRSYININRHAFDLWMKSLI 111
             GL   +  I +  +  +       S        +      + I   R   D  +  + 
Sbjct: 57  SLGLLPRLLEIPHTPVQKITYHGADTSSVTVPILKIDDTASEAGIICRRILLDALLMEIA 116

Query: 112 PASVEVYHD-SLCRKIWREDDKWHVI--FRADGWEQHITARYLVGADGANSMVRRHLY-P 167
                   D     ++  +  + + +   R  G     TA+ +VGADG++S+V R +  P
Sbjct: 117 AEEEVEVVDWCRITEVLVKGGQAYGVKGERGGGRGVSWTAKVVVGADGSDSLVARQMNMP 176

Query: 168 DHQIRKYVAIQQWFAEKHPVPFY-SCIFDNSITNCYSWSISKDGYFIFGGA-----YPMK 221
            +   + +A++ +F +   +       F   +   Y W    +      G          
Sbjct: 177 RYPEYRALAVRGYFRQVLGIRGNIEVHFPEEVLPGYVWFHPTETSQTNVGLTIPMDVVKD 236

Query: 222 DGQTRFTTLKEKMS--AFQFQFGKTVKSEKC-TVLFPSRWQDFVCGKDNAFLIGEAAGFI 278
                   LK  ++    + +F    +  +    + P          +   L+G+AAG +
Sbjct: 237 TNIKPKQALKRALASPELKERFAFAEQMGEIEAGVLPVGNPIREIHGNGFILVGDAAGLV 296

Query: 279 SASSLEGISYALDSTDILRSVLLKQ------PEKLNTAYWRATRKLRLKLFGKIVKSRCL 332
           +  S +G + A+ S  I   VL K        E     Y     K          +   L
Sbjct: 297 NPCSSDGTTNAIISARIAGEVLAKTCKGESWDEAALREYPYYLWKEIGPSLEMGGRLLGL 356

Query: 333 TAPALRKWIMRSGVAH 348
             P     ++RS    
Sbjct: 357 RTPKAIGSLIRSASRR 372


>UniRef50_C8X2V2 Geranylgeranyl reductase n=1 Tax=Desulfohalobium retbaense DSM 5692
           RepID=C8X2V2_DESRD
          Length = 384

 Score =  197 bits (501), Expect = 6e-49,   Method: Composition-based stats.
 Identities = 72/366 (19%), Positives = 120/366 (32%), Gaps = 31/366 (8%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M  FD  ++G GP+G A A+ +A    +V+ LDK          K C G++         
Sbjct: 1   MHRFDAIVVGGGPSGCAAAKGIADAGGEVLLLDK----AAFPRPKLCAGVITAKTVAVVE 56

Query: 60  RDGLTLPVDVIA-----NPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKS-LIPA 113
           R        + A                    L  +    +  + R +FD  +      A
Sbjct: 57  RVFGLDTASLHACGALKAATPRYRVVTRQRVLLEDSAPDPFRLVERRSFDHLLLQRAAAA 116

Query: 114 SVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRK 173
                 ++    I     +           +   AR ++GADG +S VRRHL P  Q R+
Sbjct: 117 GARCVTETPVTGIDPRRGEV-----KTAAGETFQARVVIGADGVHSRVRRHLTPRVQARR 171

Query: 174 Y--------VAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQT 225
           Y        V I     +         +    + + Y+W+  +    I G       G+ 
Sbjct: 172 YWRQRLAHCVEIVAPLQDLTHSHTSLGLHLGYVRHGYAWNFPRGEDIILGMCALPCRGER 231

Query: 226 RFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEG 285
                +E +    +      K        P         +D   L G+AAG       EG
Sbjct: 232 LDHAFQEFLGDIGYVGAAPFK----GHPLPYGNFLDTPVQDRVLLTGDAAGLADPLLGEG 287

Query: 286 ISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLF--GKIVKSRCLTAPALRKWIMR 343
           + +AL S ++     L  PE    AY +A        F   + ++   L    +    + 
Sbjct: 288 LYFALRSGELAAQAAL-SPEHGFFAYDKALHSEIYSDFCWAQRLRRTALFLLPVASGRLV 346

Query: 344 SGVAHI 349
           +G+A  
Sbjct: 347 AGLAQW 352


>UniRef50_UPI0001C42077 geranylgeranyl reductase family protein n=1 Tax=Methanobrevibacter
           ruminantium M1 RepID=UPI0001C42077
          Length = 432

 Score =  197 bits (501), Expect = 7e-49,   Method: Composition-based stats.
 Identities = 63/307 (20%), Positives = 119/307 (38%), Gaps = 12/307 (3%)

Query: 3   HFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            +DVAI+G GP GS+LA +LA   ++V  +DKK + G       C G++           
Sbjct: 4   DYDVAIVGAGPIGSSLAYELAQNGLKVCLIDKKKRIG---LPLQCAGIVNKRISSL---- 56

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDS 121
              +P ++I N    +       +      +     ++R AFD ++ +     ++ Y  S
Sbjct: 57  -CDIPKELILNEAKGAFIHSKNHSLTVSKKESQAYVLDRVAFDQYLFNRAREHLDTYLSS 115

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWF 181
               I  E     V F+ D   + I ++ +VGADG  S+  + +                
Sbjct: 116 KVVDIDTELG--IVQFKFDCEIKTIRSKIIVGADGPLSLSAKKVNSKLNYFNASQYLVKV 173

Query: 182 AEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQF 241
            +   + F        +   + W+I         G +   D +++   L + +   +F++
Sbjct: 174 DKIDEMSFVDLYAWGDLFPGFIWAIPVYSNIYRIGLFSEDDYKSQSKMLDDYLE-NEFRY 232

Query: 242 GKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLL 301
            +    EK     P   +     K+   LIG+AA  +  ++  GI   L+S    +  +L
Sbjct: 233 DEYEVLEKYKGKIPIYDKSNKLFKNRLILIGDAASQVKPTTGGGILIGLESVQFAKDAIL 292

Query: 302 KQPEKLN 308
                L+
Sbjct: 293 NALNTLD 299


>UniRef50_D2VJZ4 CMF receptor CMFR1 n=1 Tax=Naegleria gruberi RepID=D2VJZ4_NAEGR
          Length = 505

 Score =  196 bits (500), Expect = 8e-49,   Method: Composition-based stats.
 Identities = 58/360 (16%), Positives = 109/360 (30%), Gaps = 41/360 (11%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
             +DV I+G GP+G+  A  LA    +V+ L++K+        K CG             
Sbjct: 77  NEYDVCIVGAGPSGATCAYYLAKFGYKVLVLEQKY----FPREKTCGDGCTAKTLAYLKE 132

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYIN-------------INRHAFDLWM 107
            G+   ++            +     L+                      I R   D  +
Sbjct: 133 MGVLQELEKEGKVASMGSGGIVGPNGLSFIENSGATIEKISGDNNWTPKAIKRIHMDEKV 192

Query: 108 KSLIPA-SVEVYHDSLCRKIWRE---DDKWHVIF----RADGWEQHIT--ARYLVGADGA 157
                    ++       K+ R       W ++     + DG  + +   A  LV ADGA
Sbjct: 193 ARACQKMGADLKEGMDVTKVSRNFVGLKGWSIVANHTPKEDGETKQVKFLASVLVCADGA 252

Query: 158 NSMVRRHLYPDHQIRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGA 217
            S +   L   ++  + ++ + + +           +   +   Y          +    
Sbjct: 253 PSKLATSLKMVNEEPQGISSRVYVSNHKMETNCIIFYPKPVLPGYCSMFCHSDGDVSLCT 312

Query: 218 YPMKDGQTRFTTLKEKMSA-------FQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFL 270
           Y +  G+     L +                G   + ++    +           DN  +
Sbjct: 313 YIVPGGKPTKDDLGKLHEYCTTEDPLITKALGPNPQWQQMKAAYLRLGGISNSYGDNILV 372

Query: 271 IGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKLNTA------YWRATRKLRLKLFG 324
           IG+A G I+  + EGI YA+DS  +   VL    +  + +      Y           F 
Sbjct: 373 IGDACGLINPMTGEGIHYAMDSGKMAAEVLGDAIKGGDLSKNKLKLYQDMWEYQFANDFH 432


>UniRef50_UPI000050FC1D geranylgeranyl reductase n=1 Tax=Brevibacterium linens BL2
           RepID=UPI000050FC1D
          Length = 433

 Score =  195 bits (496), Expect = 2e-48,   Method: Composition-based stats.
 Identities = 65/393 (16%), Positives = 130/393 (33%), Gaps = 50/393 (12%)

Query: 1   MEHF--DVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSF 58
           M  F  +V ++G GPAGSA+   LA     + + +K         K CG  L P A +  
Sbjct: 1   MNEFSAEVIVVGAGPAGSAIGAYLAQAGHEVIILEKSG---FPRDKICGDALTPRAVKEV 57

Query: 59  IRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQR------SYININRHAFDLWM-KSLI 111
              G+  P +     +   ++ +     L  ++          +   R   D    +   
Sbjct: 58  GYLGMATP-ESEGWHKNRGLRLIGGGHRLEIDWPDIDGTPNFGLTKPRMGMDEAFARHAQ 116

Query: 112 PASVEVYHDSLCRKIWREDDKWHVIF---------RADGWEQHITARYLVGADGANSMVR 162
            +   ++           +D W             R  G E H +A  ++ ADG +S + 
Sbjct: 117 RSGARLFEQVKAMSPDIGEDGWIQGVHASGTDHRGRRVGPEAHFSAPIVIAADGVSSRLA 176

Query: 163 RHLYPDHQIRK--YVAIQQWFAEKHPVPFYSCIF----------DNSITNCYSWSIS-KD 209
             +  + +  +   VA++ + +       Y   +          ++ +   Y W     D
Sbjct: 177 VAMGLEKRDDRPMGVAVRAYHSSPRHADDYIESWVEMRSRNSAGESEVLPGYGWLFPLGD 236

Query: 210 GYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKC-------TVLFPSRWQDFV 262
           G    G        Q      +  M  +    G     ++        +   P  +    
Sbjct: 237 GTINIGAGLLDSSPQFGSVDFRTMMGQWIADMGHEWGIDETTSLGPIKSAALPMAFNRTP 296

Query: 263 CGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVL---LKQPEKLNTAYWRATRKLR 319
                  L+G++ G ++  + EGI YAL+S  +   V+    + P+ +     +    L 
Sbjct: 297 HFHKGLLLVGDSGGMVNPFNGEGIDYALESARLAAEVISTYSRYPKHVMREKLQEYPALV 356

Query: 320 LKLFGKIVKSRCLTA-----PALRKWIMRSGVA 347
               G       + +     PAL ++ ++ G+ 
Sbjct: 357 GDSLGGYFTLGRVFSAIIGHPALMQFGIKYGMG 389


>UniRef50_Q1PX22 Putative uncharacterized protein n=1 Tax=Candidatus Kuenenia
           stuttgartiensis RepID=Q1PX22_9BACT
          Length = 351

 Score =  193 bits (491), Expect = 9e-48,   Method: Composition-based stats.
 Identities = 79/337 (23%), Positives = 140/337 (41%), Gaps = 28/337 (8%)

Query: 4   FDVAIIGLGPAGSALARKL-AGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +D  ++G GP+G+A A++L    ++V+ L+KK         K C G++   +Q    R  
Sbjct: 5   YDAVVVGSGPSGAAAAKRLTGEGLRVLVLEKKKL----PRYKICSGIIFKKSQEITERYF 60

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQR-----SYININRHAFDLWMKSLIPASVEV 117
             +P  V   P++              ++          N+ R  +D W+ S   +  EV
Sbjct: 61  GRIPDAVYVQPKLLKGVRFWSDLGNYSDWPFSKDSEGAPNVWRSEYDYWLIS--NSGAEV 118

Query: 118 YHDSLCRKIWREDDKWHVIF--RADGWEQHITARYLVGADGANSMVRRHLYP--DHQIRK 173
              ++ +    E +   V +    +   +    RYL+ A+G+ S +R  L P  +  ++ 
Sbjct: 119 MDCAVFKGFETEGNAVVVHYYDARENKIRQAKCRYLISAEGSVSCIRAMLSPAFERNVKW 178

Query: 174 YVAIQQWFAEKHPVP--FYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLK 231
           ++A Q ++  +  +   FY    D      Y+W   KD   +FG +   + G      L 
Sbjct: 179 FIAYQNYYEGQSSLDPYFYHGFLDQKYGEVYAWFSVKDDLQVFGTSV--RKGAKILPCLN 236

Query: 232 EKMSAFQFQFGKTV----KSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGIS 287
                 + + G  +    +   C         +F  GK N  L+GEAAGF++A   EGIS
Sbjct: 237 AFHEMLEKEHGLALKKLVRKTSCLGNTMCASGNFYLGKGNILLVGEAAGFLNAF-GEGIS 295

Query: 288 YALDSTDILRSVL---LKQPEKLNTAYWRATRKLRLK 321
            AL S       +   +K  E + +AY   T+K R +
Sbjct: 296 CALSSGLFAAEAICACIKSGEDVISAYTELTKKERRQ 332


>UniRef50_B4AWE1 Monooxygenase FAD-binding n=1 Tax=Cyanothece sp. PCC 7822
           RepID=B4AWE1_9CHRO
          Length = 432

 Score =  193 bits (490), Expect = 1e-47,   Method: Composition-based stats.
 Identities = 59/377 (15%), Positives = 110/377 (29%), Gaps = 33/377 (8%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           M  +++AIIG GPAG++LA  LA   + +A+ +K            G  L P        
Sbjct: 1   MN-YEIAIIGGGPAGASLATYLARAGKSVAIFEKSDFPRFHI----GESLLPATMPILQD 55

Query: 61  DGLTLPVDVIANPQIFSVKTVDV----------AASLTRNYQRSYININRHAFDLWMKSL 110
            G+   +      +       D             + +    R    + R  FD  +   
Sbjct: 56  LGVYERMRSTFLNKPGGCWYYDDTPVMSDFAKCRETASFKDFRHAFMVERGEFDRILLDN 115

Query: 111 IPA-SVEVYHDSLCRKIWREDD---KWHVIFRADGWEQHITARYLVGADGANSMVRRHLY 166
                V V+   L R+   E +      V        + I    +    G  S++     
Sbjct: 116 ARDHGVRVFQHHLVREAIWEGERMTGLQVKDLQTMEGKSIRTEMVFDCSGYRSVIASQRN 175

Query: 167 PDHQIR-KYVAIQQWFAEKHPVPF--YSCIFDNSITNCYSWSISKD-GYFIFGGAYPMKD 222
                R K +AI   +  +                 + + W I  D      G    + +
Sbjct: 176 LRKPNRLKKMAIFAHYRAEALEERLKQGWFVGQMFYDGWLWLIPIDKDRISIGVVTTLDN 235

Query: 223 GQTRFTTLKEKMSAFQFQF--------GKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEA 274
            +    + ++ +  +                +     +     +       D   L+G+A
Sbjct: 236 YKKASISPEQFLDHYIRTLSLTRKGLGKNIERVSDIYLYGNLGYSSERIFGDRWALVGDA 295

Query: 275 AGFISASSLEGISYALDSTDILRSVLLKQPEKL--NTAYWRATRKLRLKLFGKIVKSRCL 332
           A FI      G+  A+DS   +  V L+                K   +    ++     
Sbjct: 296 AVFIDPCYSSGVHLAMDSAREIARVYLEHGYDARSLQNALSKYEKRLRQHEELVLMLVDS 355

Query: 333 TAPALRKWIMRSGVAHI 349
              A R   +R  V ++
Sbjct: 356 FYMASRNKFLRFLVKNL 372


>UniRef50_D1JEF0 Putative uncharacterized protein n=1 Tax=uncultured archaeon
           RepID=D1JEF0_9ARCH
          Length = 412

 Score =  192 bits (488), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 58/353 (16%), Positives = 109/353 (30%), Gaps = 33/353 (9%)

Query: 1   MEH-FDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSF 58
           M+  FDV I G GPAG + A   A  K   + ++        G+     G    +A + F
Sbjct: 1   MKKNFDVIIAGGGPAGLSAAIIAARNKCDTLLVESSK---AFGYPIHDSGATFSEAIKDF 57

Query: 59  IRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRS-YININRHAFDLWMKS-LIPASVE 116
                 L   VI N              ++          + R   +  +        VE
Sbjct: 58  -----NLSKGVITNRIDGVTIVSPKGYVVSTKLGEGIGYILERRELNRELAKIAANEGVE 112

Query: 117 VYHDSLCRKIWREDDKWHVIFRA---DGWEQHITARYLVGADGANSMVRRHLYPDHQI-R 172
           +            +     +       G      ++ ++ A G N+++ + +     +  
Sbjct: 113 IKMPVKAVSPILSNGFVAGLQTKELIGGDNIEYKSKLVIDATGVNAVIAKAVGIHPGMSN 172

Query: 173 KYVAIQQWFA---EKHPVPFYSCIFDNS--ITNCYSWSISK-DGYFIFGGAYPM--KDGQ 224
              AI   +     +   P +  ++  S    + Y W   K DG    G        +  
Sbjct: 173 IRWAIGAEYEMTNVELDNPNFIELYFGSQIAPSGYGWIFPKGDGVANVGVGITHISNERI 232

Query: 225 TRFTTLKEKMSAFQ---FQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISAS 281
             F  L   +  +     +       E    + P          D   ++G+AA  +S  
Sbjct: 233 NPFKYLSRFIKEYPVTSKKLKNAQPLEYHVGILPIGPMFDQIVSDGLMIVGDAACQVSPH 292

Query: 282 SLEGISYALDSTDILRSVLLKQPEKLNTA------YWRATRKLRLKLFGKIVK 328
             EGI + + + +I   V +    K NT+      Y +  +K     +  + K
Sbjct: 293 LGEGIRFVMKAGEIAGEVAVDAINKNNTSKNNLTQYEKQVKKEIYPNYRLLYK 345


>UniRef50_B5YGK5 Geranylgeranyl hydrogenase, putative n=1 Tax=Thermodesulfovibrio
           yellowstonii DSM 11347 RepID=B5YGK5_THEYD
          Length = 378

 Score =  192 bits (488), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 76/372 (20%), Positives = 128/372 (34%), Gaps = 36/372 (9%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
             +V ++G GPAGS  AR LA K     L +K       F+KPCGG +     + F    
Sbjct: 2   QCEVLVVGGGPAGSTAARLLAEKGIETVLIEKDLT----FNKPCGGGIPSAGLKEFNILN 57

Query: 63  LT---LPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYH 119
                +P +++   +IF   +  +  SL        +  NR +FD +M+ L   S     
Sbjct: 58  KLQNQIPFNIVTKVKIFPPFSEPIEVSLQ---GGEILIFNRQSFDSFMRKLAEKSGVKII 114

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQ 179
           ++    I   + K  V  +  G    I ++Y++ ADG NS V            +     
Sbjct: 115 EAELINIE--NSKLTVR-KKTGEVLEIYSKYIIAADGVNSRVCSIKGWSKPEYYWTVSLH 171

Query: 180 WFAEKHPVPFYSCIFDNSITN--CYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAF 237
                         +  +      YSW      YF  G      +   +  TL +     
Sbjct: 172 VLENFIDTKDTCEFWFGNSHASFFYSWVFPGVDYFSVGTGA---EDIKKLKTLIDNFVEK 228

Query: 238 QFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILR 297
           +F     + S K       +W      K+N    G+  G +   S EGI Y++ S     
Sbjct: 229 RFAGKLNINSFKLRAYKIPKWGRRSFFKENVIFCGDTLGTVMPISFEGIYYSMKSAQFAS 288

Query: 298 SVLLKQPEKLNTAYWRATR-----------------KLRLKLFGKIVKSRCLTAPALRKW 340
             ++++   L    W                       R+  +  I ++  +   A+  W
Sbjct: 289 EAIVQKDLNLYKKLWDENFLKQFSIMKKFQDYMFGNDERIDNWLNIHRNPAIQELAMALW 348

Query: 341 IMR-SGVAHIPQ 351
           + +  G   IP 
Sbjct: 349 LRKEHGSKLIPL 360


>UniRef50_Q58915 Uncharacterized protein MJ1520 n=11 Tax=Methanococcales
           RepID=Y1520_METJA
          Length = 387

 Score =  192 bits (488), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 52/339 (15%), Positives = 107/339 (31%), Gaps = 19/339 (5%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
             +DV IIG GP G      +    +V+ +++    G       C GL++ +  +     
Sbjct: 4   NDYDVVIIGGGPVGCITGEYI-KNGRVLIVEEHQSIG---VPLQCAGLISKNGVKELGNP 59

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDS 121
                   + N    +      +     N         R   D  +        +    +
Sbjct: 60  ------KGVVNKVRGAYIYSKNSMVKIGNEGIRAYIFERKVMDKDIAIRAAKKCDFLLKA 113

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYV---AIQ 178
              KI ++ + + V     G +  +  + +VGADGA ++  + L   +   + +      
Sbjct: 114 -YGKIEKDKNGYKVEITHLGEKITLNPKIIVGADGAKTITGKKLGLVNNKNREILSSCQF 172

Query: 179 QWFAEKHPVPFYSCIFDNSIT-NCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAF 237
           +    +    F     D   +   ++W I      +  G     +   +      +    
Sbjct: 173 EMVNAEVDDDFVYIFLDRKYSERFFTWIIPMGKDRVRVGLIDRGNCYNKLIRFINENKIA 232

Query: 238 QFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILR 297
           +        +E  T   P  + D    KDN  L+G+AA  +   S  G+ +      I  
Sbjct: 233 KEILKNATITEFSTGSLPIGYLDKTF-KDNVLLVGDAACHVKPLSGGGLYFGAMGGKIAG 291

Query: 298 SVLLKQPEKL---NTAYWRATRKLRLKLFGKIVKSRCLT 333
            V+ K   +       Y +  ++         ++ R L 
Sbjct: 292 EVISKYLNEDIENLELYDKRWKETFGSEIKNGLRVRKLF 330


>UniRef50_B4D801 Tryptophan halogenase n=1 Tax=Chthoniobacter flavus Ellin428
           RepID=B4D801_9BACT
          Length = 430

 Score =  192 bits (488), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 60/335 (17%), Positives = 107/335 (31%), Gaps = 30/335 (8%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
             ++V IIG GPAG+  A  LA K + + + +K +          G  L P    +  R 
Sbjct: 13  NQYEVIIIGAGPAGTTTAALLAEKGRRVLVLEKEKFPRYHV----GESLMPYCWFTLNRL 68

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNY---------QRSYININRHAFDLWMKSLIP 112
           GL   ++ IA  + +SV+ V      +  +           +   + R  FDL +     
Sbjct: 69  GLVEEMNHIAYTKKYSVQFVTQDGRQSAPFYFFQHYDHPSSTTWQVERADFDLMLLKNAR 128

Query: 113 A-SVEVYHDSLCRKIWREDDKWHVIFRA---DGWEQHITARYLVGADGAN--SMVRRHLY 166
           A   EV   +   ++ +++    +   A   +G      A   V   G    S+ R    
Sbjct: 129 AKGAEVRELTPVTRLLKDESGKVIGVEARDENGATHEFYAPMTVDCSGREQISIARDGWR 188

Query: 167 PDHQIRKYVAIQQWFAEKHPVPFYSC---IFDNSITNCYSWSIS-KDGYFIFGGAYPM-- 220
                   +AI  +F      P                + W I  K+     G       
Sbjct: 189 VKDAKLNKIAIWTYFRGAKRDPGIDEGNTTVAYVEGRGWFWYIPLKNDTVSVGIVAEKDY 248

Query: 221 -----KDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAA 275
                KD         E+ +  +       +  +  V     ++   C  D   L G+A 
Sbjct: 249 LFSESKDPAKIMQREIERNAWIKEHLSMGEQFGEYFVTSEFSYRSKYCAADGLLLAGDAF 308

Query: 276 GFISASSLEGISYALDSTDILRSVLLKQPEKLNTA 310
            F+      G+  AL S ++    +       + +
Sbjct: 309 AFLDPVFSSGVFLALKSGEMAADAVDAALTTGDFS 343


>UniRef50_A2BVI2 NAD binding site n=7 Tax=Prochlorococcus marinus RepID=A2BVI2_PROM5
          Length = 377

 Score =  191 bits (487), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 58/344 (16%), Positives = 117/344 (34%), Gaps = 16/344 (4%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           M+ FD  IIG G +GS+ A  L+ K   + + +K   G     KPC G +   + + ++ 
Sbjct: 1   MKEFDAIIIGGGLSGSSTALNLSKKGYSVLIIEKEATG---IIKPCAGGM-ASSMKQYLP 56

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMK-SLIPASVEVYH 119
             +   ++       F  ++ D   +   + +  +  I R   D  +    +   +E+  
Sbjct: 57  LDIDQAIESKIRNVEFRWESSDN-VNADLSGESPFWIIRREKLDQLLLDEALKNGIEILR 115

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYV-AIQ 178
            +   +I  ++  W +       +    ++YLV ADG+ S    +     +  K+   I 
Sbjct: 116 PAQVEEIISQNKTWRIKCSH---KDIYKSKYLVIADGSQSQWAGYFNLGPRKPKFANTIA 172

Query: 179 QWFAEKHPVP-FYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEK-MSA 236
                   +P          I   ++W+         G    + +       L  K + +
Sbjct: 173 LRLKGLGNIPKDSVRFEFGFIKYGFAWAFPLKDSVNIGLGTFINNKLLEDEALNNKVLKS 232

Query: 237 FQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDIL 296
           F F+     K  K   ++           D    +G+AA        EGI  +L S+   
Sbjct: 233 FGFEDLSFEKVHKKLRIWNGTH---KLNGDRVVAVGDAASLCDPFLAEGIRPSLISSYFA 289

Query: 297 RSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKW 340
              + +     N +            +GK +      A    ++
Sbjct: 290 AESIHQCLSS-NKSDLNTYSIKINNEWGKSMAWGKRIAQIFYRF 332


>UniRef50_B0JID7 Geranylgeranyl reductase n=8 Tax=Cyanobacteria RepID=B0JID7_MICAN
          Length = 378

 Score =  191 bits (487), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 70/325 (21%), Positives = 125/325 (38%), Gaps = 17/325 (5%)

Query: 20  RKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVK 79
             LA K + I +  K +       KPCGG ++P  ++ F  D  T  ++       F+ K
Sbjct: 18  YHLAKKGRTILILDKAKL---PRYKPCGGGVSPAIKQWFDFDF-TPVIENTVTQVEFTWK 73

Query: 80  TVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVYHDSLCRKIWREDDKWHVIFR 138
             D  A+   N       + R  FD ++ +  I     +  +S   +I    D W V   
Sbjct: 74  QGDA-ATTKLNMLEPMWMVQRDRFDDFLGQQAIAVGATIQDNSEVTQIKFVQDHWQVTTS 132

Query: 139 ADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEKHPVPFYSCIFD-NS 197
                   + +YL+ ADG      R L    + +   A  +    +  +P     FD  S
Sbjct: 133 QG----TFSGKYLIAADGVKGNTSRWLGLPAKNQAIGATLEITNAEATIPPQKAFFDFGS 188

Query: 198 ITNCYSWSISK-DGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPS 256
           + N Y W+  K +GY I GG +    G  +   LK+++  +  Q G  ++  + +    +
Sbjct: 189 LKNGYIWAFPKSNGYTISGGCF---KGSIKSEELKKQLLNYARQKGWNLEDYRYSEYALA 245

Query: 257 RWQ-DFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRAT 315
            W  +      NA + GEAAG +     EGI  A+ +       + +     N A     
Sbjct: 246 LWNGNKPLHAQNALITGEAAGILDPLIGEGIRPAILTGVKAAEAIDRALAGDNQALAG-Y 304

Query: 316 RKLRLKLFGKIVKSRCLTAPALRKW 340
            ++  + +G+ +      A    ++
Sbjct: 305 SRIIREEWGEDMALAAKLAGLFYQF 329


>UniRef50_Q8DJ25 Tll1404 protein n=7 Tax=Cyanobacteria RepID=Q8DJ25_THEEB
          Length = 378

 Score =  191 bits (487), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 62/339 (18%), Positives = 118/339 (34%), Gaps = 17/339 (5%)

Query: 20  RKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVK 79
             LA + + + + +K         KPCGG ++P  Q  F  D  +  + +     + + +
Sbjct: 18  YHLAKRGRRVLVLEKEAL---PRYKPCGGGVSPQVQSWFDFDF-SPAISLKVTQMVCTWQ 73

Query: 80  TVDVAASLTRNYQRSYININRHAFDLWMKSLI-PASVEVYHDSLCRKIWREDDKWHVIFR 138
             +    L    ++    + R  FD ++         E+   +    +    D+W V   
Sbjct: 74  GEEAQ-LLEFPPEQPMWMVRRDVFDYFLIQQAQRQGAELRPQTPVTGLTWGGDRWQVHT- 131

Query: 139 ADGWEQHITARYLVGADGANSMVRRHLYP-DHQIRKYVAIQQWFAEKHPVPFYSCIFDNS 197
                   TA+YL+G DGA   + + L   D Q R   AI+   A        +      
Sbjct: 132 ---PSGDFTAQYLIGCDGAKGSMAKWLGFKDRQQRVGAAIEIEAAMPDHSLTAAHFDFGR 188

Query: 198 ITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSR 257
           + N Y W+  K   +  G          R   L+   + +   FG      K        
Sbjct: 189 LHNGYIWNFPKRDGYSIGVGTV---ALGRKQNLRAIGAEYAKTFGVDFNQVKVYGHPLYC 245

Query: 258 WQ-DFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATR 316
           WQ        NA L GEAA  +   + EGI  +L +  +    + +       A    ++
Sbjct: 246 WQQHQRLHTQNALLAGEAACVVDPFTAEGIRPSLLTGMLAAQAIDRALSGDPEALTNYSQ 305

Query: 317 KLRLKLFGKIVKSRCLTAPALR--KWIMRSGVAHIPQLK 353
           +++ +    ++ ++ L+    R  +      V  +   +
Sbjct: 306 QVQQEWGADMIWAKRLSTLFYRMPRTAYELAVKRLSARQ 344


>UniRef50_A5FDA0 FAD dependent oxidoreductase n=2 Tax=Bacteroidetes
           RepID=A5FDA0_FLAJ1
          Length = 375

 Score =  191 bits (487), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 59/372 (15%), Positives = 125/372 (33%), Gaps = 42/372 (11%)

Query: 5   DVAIIGLGPAGSALARKL-AGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           DV IIG G AG   A  L    ++VI ++K          K CG  ++ +        G 
Sbjct: 6   DVLIIGGGLAGLTAAIHLSQKNLKVILIEKS----NFPRHKVCGEYISNEILPYLTWLGA 61

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLC 123
            +  ++  +       T     +           I+R+A D ++     A+  +      
Sbjct: 62  DV-TELNPSSISKFEFTASNGKTAMVELPLGGFGISRYALDDFLYQKAIANHCLIIKENV 120

Query: 124 RKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPD--HQIRKYVAIQQWF 181
             +   DD + V        Q +TA+ ++GA G  S + + L     H+   ++A++  +
Sbjct: 121 IDVSFSDDLFTVT----SSNQILTAKIVLGAFGKRSNLDQALDRSFFHKKSPWLAVKAHY 176

Query: 182 AEKHPVPFYSCIFDNSITNCYSWSI-SKDGYFIFGGAYPMKDGQ--TRFTTLKEKMSAFQ 238
           +        +    ++    Y      ++              +        +E +    
Sbjct: 177 SGNLEDDLVAL---HNFKGGYCGVAKVENNIINICYLADYATFKQYKNIQDYQEGVLYKN 233

Query: 239 FQFGKTVKS-----EKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDST 293
                  ++     EK   +    ++     +++  +IG+ AG I      G++ A+ S 
Sbjct: 234 KHLKAVFENSMLLFEKPLTISQISFEKKKAVENHIIMIGDTAGLIHPLCGNGMAMAVHSA 293

Query: 294 DILRSVLLKQPEK-------LNTAYWRATRKLR------LKLFGKIVKSRCLTAPALRKW 340
            I   ++L+           L   Y +  +K         ++   I+  R +T       
Sbjct: 294 KIASELILEYYSDDKASRKVLEKKYTKEWKKHFGKRIWMGRILAHILTHRTITN------ 347

Query: 341 IMRSGVAHIPQL 352
           +  +  A  P+L
Sbjct: 348 VFTAITASFPKL 359


>UniRef50_B4U8N3 Geranylgeranyl reductase n=1 Tax=Hydrogenobaculum sp. Y04AAS1
           RepID=B4U8N3_HYDS0
          Length = 348

 Score =  191 bits (487), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 67/323 (20%), Positives = 109/323 (33%), Gaps = 23/323 (7%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQ-RSFIR 60
             DV IIG G AGS+ A +LA K   VI +D +   G       C   +      + F  
Sbjct: 6   KTDVLIIGGGLAGSSAAHQLAKKGVDVIIVDSRKTIG---VPVQCAEFIPKQLMQKKFED 62

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDL-WMKSLIPASVEVYH 119
                 V  I N         D     + +     + ++R  FD    +  I +    + 
Sbjct: 63  YFKNSVVQEIENMLTIEP---DNKKVYSGSK---GVMVDRKVFDANIFQEAIKSGARAFL 116

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQ 179
            ++    +   DK   I +A     ++   Y+VGADG  S V   +    +    V  Q+
Sbjct: 117 KTIFIGFY---DKNTAILKAKDDVYYVEFDYIVGADGPRSSVMEKV-FSKKHELAVCAQR 172

Query: 180 WFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQF 239
               K P+     +F   I   Y W   K+ Y   G        +     + E       
Sbjct: 173 RCKLKEPLKDIVIVFREYIKGGYGWIFPKNNYANVGIGID-TAFKDDPKYVLELFIKDAV 231

Query: 240 QFGKTVK--SEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILR 297
             G       E      P    D      N  L G+A GF    +  GI  A+ S ++L 
Sbjct: 232 SMGFIENNCDESSGGFLPLDGID-TLVSSNVALCGDAGGFCHPITGGGIPQAVVSGNMLA 290

Query: 298 SVLLKQPEKLNTAYWRATRKLRL 320
             +L+       ++   ++++  
Sbjct: 291 QYILEND---LESFEEESKEIYG 310


>UniRef50_A9A398 Geranylgeranyl reductase n=4 Tax=Thaumarchaeota RepID=A9A398_NITMS
          Length = 402

 Score =  191 bits (486), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 67/332 (20%), Positives = 120/332 (36%), Gaps = 27/332 (8%)

Query: 4   FDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +D+ ++G GPAGS+ A   +   ++VI ++K+        +    G+        F    
Sbjct: 5   YDLVVVGGGPAGSSAAYTASKNGLKVILIEKEESIAESVRT---SGVTWIQNIEEF---- 57

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPA-SVEVYHDS 121
             +P D     + F   + +   S+     RS +   R  +  W+ S   A   E+  ++
Sbjct: 58  -GIPEDCYNPVKNFEFYSPNNKVSIGDTVARSAVLDVRKTY-RWLASQAEAQGTEIVVNT 115

Query: 122 LCRKIWREDDKWHVIFRADGWEQHIT--ARYLVGADGANSMVRRHLYPDHQIRKYVAIQQ 179
             + + +++    +  +A   E+ I    + ++ A G  S V + +    Q  ++ A  +
Sbjct: 116 TVKDVIKDESGKIIGVKAIQNEKEIEFFGKVVIDASGFQSTVAKSMGFVKQWERFGAGAE 175

Query: 180 WFAEKHPVPFYSCIF---DNSITNCYSWSIS-KDGYFIFGGAYPMKDGQ----TRFTTLK 231
           + A+   V   +      +      Y+W     D     G      D       R   L 
Sbjct: 176 YEAKVEHVKADTWWLMVGEKYSPAGYAWIFPLGDNIARIGVGIGKPDSPVDPTARLKELI 235

Query: 232 EKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALD 291
           E         GK    E    L P+         DN  L+G++AG  +   LEGI YA+ 
Sbjct: 236 ENKEGPIANLGKIEPIEFHYGLIPNDGLSRKTVYDNLILVGDSAGQANPLVLEGIRYAIK 295

Query: 292 STDILRSVLLKQ------PEKLNTAYWRATRK 317
              I   V  K        EK  + Y    +K
Sbjct: 296 FGRIAGDVASKAIKANDTSEKKLSEYEDNWKK 327


>UniRef50_D1CHF7 Geranylgeranyl reductase n=1 Tax=Thermobaculum terrenum ATCC
           BAA-798 RepID=D1CHF7_THET1
          Length = 413

 Score =  190 bits (483), Expect = 7e-47,   Method: Composition-based stats.
 Identities = 71/350 (20%), Positives = 111/350 (31%), Gaps = 15/350 (4%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
             +DV ++G GPAGSA A +LA     + L  K +       K CG  L P A       
Sbjct: 25  GKYDVVVVGAGPAGSACAWELARHGVRVLLLDKSE---FPRDKTCGDGLTPRAVSVLEGM 81

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQ-RSYININRHAFDLWMKSLIPA-SVEVYH 119
           GL   V  +               S T     R  + + R   D  +     +   E   
Sbjct: 82  GLAREVAGMGGRVSQVRVVGPGGTSTTLGMPGRGGLVVPRLRLDDALLRRATSVGAEFEA 141

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGAN-SMVRRHLYPDHQIRKYVAIQ 178
            +    +  E     V          + AR +V A GA+  ++ R      + R   A +
Sbjct: 142 PARAEAVELEGQHALVRLEDGRG---VRARMVVVATGASPRLLERSGLVAARPRLLAASR 198

Query: 179 QWFAEKHP-VPFYSCIFDNSITNCYSWSIS-KDGYFIFGGAYP-MKDGQTRFTTLKEKMS 235
            +F      V      F       Y W      G F  G       +G T     +    
Sbjct: 199 AYFECPAAQVEEMVFSFQGVTLPGYGWIFPLGGGRFNVGAGVLARHEGSTARKEFEAFTR 258

Query: 236 AFQ-FQFGKTVKSEKCTVLFPSR--WQDFVCGKDNAFLIGEAAGFISASSLEGISYALDS 292
           +    +     + E     FP R  +           ++GEAAG ++  + EGI YAL+S
Sbjct: 259 SRLCSRLLPGARREGPVRGFPLRTDFLRSRLWAPGVVMVGEAAGLVNPLTGEGIDYALES 318

Query: 293 TDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIM 342
             I    + +   +         R+LR +          L      +  +
Sbjct: 319 GVIAGRHVREMLSRGEIEARAYERELRSRFSELFRTCERLRWLCRSRLAV 368


>UniRef50_Q1VX49 FAD dependent oxidoreductase, putative n=1 Tax=Psychroflexus
           torquis ATCC 700755 RepID=Q1VX49_9FLAO
          Length = 371

 Score =  189 bits (482), Expect = 9e-47,   Method: Composition-based stats.
 Identities = 66/360 (18%), Positives = 132/360 (36%), Gaps = 30/360 (8%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M  +DV IIG G AG   A  L+   +QV+ L+K+    T    K CG  ++ +      
Sbjct: 1   MNTYDVIIIGGGLAGLTSAIDLSKDGLQVLLLEKE----TYPKHKVCGEYVSNEISPYLN 56

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAA-SLTRNYQRSYININRHAFDLWMKSLIPASVEVY 118
           R G+    +     +I S++  D     +          I+R+AFD  +     A+   +
Sbjct: 57  RLGVN--FETTPPDEIHSLQLSDRKGQLVEIKLPLGGFGISRYAFDHLLFKKAKANGVDF 114

Query: 119 HDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDH--QIRKYVA 176
                  +   DD++ +        Q   +   +G+ G  S + + +      Q   ++ 
Sbjct: 115 VFETVTDVEFIDDRFTIKTAQ----QTFMSILAIGSFGKRSNLDKKMDRSFITQKTPWIG 170

Query: 177 IQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTR--FTTLKEKM 234
           I+  +           + +         S ++ G   F         +          K+
Sbjct: 171 IKAHYTSSDFPEGSVQLHNFE-GGYCGLSKTETGAVNFCYLAHYDTFKKANSIEDFNHKI 229

Query: 235 SAFQFQFGKTVKS-----EKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYA 289
            +        +++     EK   +    +Q+    + +  + G++AG I      G++ A
Sbjct: 230 LSQNPHLKSFLETSKMDFEKHLAISQVSFQNKKAVEHHMLMAGDSAGLIHPLCGNGMAMA 289

Query: 290 LDSTDILRSVL-----LKQPEKLNTAYWRATRKLRLK--LFGKIVKSRCLTAPALRKWIM 342
           + S  ++ + +      K  +KL   Y R  +K   K  +FG I + + L  P L ++ M
Sbjct: 290 IHSAKLVSNEIKSFFKHKNRDKLEANYSRIWKKTFQKRLIFGSIFQ-KILLQPQLTRYGM 348


>UniRef50_Q0BPD7 Dehydrogenases (Flavoproteins) n=1 Tax=Granulibacter bethesdensis
           CGDNIH1 RepID=Q0BPD7_GRABC
          Length = 449

 Score =  189 bits (480), Expect = 2e-46,   Method: Composition-based stats.
 Identities = 67/386 (17%), Positives = 118/386 (30%), Gaps = 44/386 (11%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
            DV I+G GPAG   A  LA K + + L +K +          G  L P   +   R GL
Sbjct: 21  CDVLIVGAGPAGCTAAYLLAEKGRDVVLLEKERHPRFHI----GESLLPRNLQLIERLGL 76

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQRS---------YININRHAFDLWM-KSLIPA 113
           T  +      +  +    D        +  +            + R  FD  + +S    
Sbjct: 77  TEDIATFGVFKPGAEFISDDHGGKDTKFCFADALDKTFTHSWQVKRADFDAALFRSARDK 136

Query: 114 SVEVYHDSLCRKIWREDDKWHVIFRA-------DGWEQHITARYLVGADGANSMVRRHLY 166
             +V        I   +       RA        G   H   RY++ A G ++ +   + 
Sbjct: 137 GADVIDGMRVTTIRFPEGVPEGSARAIVEAVDEAGNAHHFAPRYVIDASGRDTFLGSKVG 196

Query: 167 PDHQIRKY--VAIQQWFAEKHPVP--FYSCIFDNSITNCYSWSIS-KDGYFIFGGAYPMK 221
              +       A+   F    P P      I    +   + W I   D     G     +
Sbjct: 197 GKKRNPHNNTAALYAHFRHVTPRPCDRTGYITICLVEGGWFWMIPLPDDITSVGFVGTQE 256

Query: 222 DGQTRFTTLKEKMSAFQF-------QFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEA 274
             + R  +L++ +            +  +  +  K T      +           +IG+A
Sbjct: 257 AFKQRKGSLEDFLDTRIAASPSVSSRMMQAERISKVTATGNYSYSCERLSGPGWMMIGDA 316

Query: 275 AGFISASSLEGISYALDSTDILRSVL---LKQPEKLNTAYWRATRKLRLKLFGKIVKSRC 331
             F+      G+  A+ S ++   V    L  P        +   K+R  +         
Sbjct: 317 FAFLDPVFSSGVLLAMTSGEMGAEVADLWLDNPAAARKKLKKVEAKIRHAIGTLSWLVYR 376

Query: 332 LTAPALR--------KWIMRSGVAHI 349
           +  P LR        ++ MR G+  +
Sbjct: 377 INKPVLRDMFMSPNNRFRMRDGLVSL 402


>UniRef50_A0B5F9 Geranylgeranyl reductase n=1 Tax=Methanosaeta thermophila PT
           RepID=A0B5F9_METTP
          Length = 368

 Score =  189 bits (480), Expect = 2e-46,   Method: Composition-based stats.
 Identities = 63/350 (18%), Positives = 108/350 (30%), Gaps = 48/350 (13%)

Query: 4   FDVAII------------GLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLA 51
           +D+ +I            G G             + V+ ++K+         KPCGG L+
Sbjct: 2   YDLIVIGGGPAGASAALEGAGL-----------GLSVLLIEKEK----FPRYKPCGGALS 46

Query: 52  PDAQRSFIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSL 110
             A+         +P +VI               +     +R    + R  FD  + +  
Sbjct: 47  EKARSYLR---FRIPDEVIDAEVSRIRIFFRDRCAEISRPERLSTLVTRSVFDDILVRRA 103

Query: 111 IPASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQ 170
             A  EV        I  ED    ++       +    R LV ADG   M+ R + P   
Sbjct: 104 ADAGAEVLFGKKATGISEEDGCVRIMA-----GESYKGRLLVLADGHTGMLSRKICPGDG 158

Query: 171 IRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTL 230
           +R    + +  AE+        I    +   Y+W      Y   G              +
Sbjct: 159 MRGVCLVSEVAAEETN--DCMEIHFGEVDRGYAWVFPHGSYLSVGAGGLGSSNIRVI--M 214

Query: 231 KEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYAL 290
              M A  F      +        P        G     L G++AG +   + EGI+YA+
Sbjct: 215 DRLMRARGF------RGRIHGHTIPLSGPSRYLGGRRTMLCGDSAGMVDPFTGEGIAYAV 268

Query: 291 DSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKW 340
            S  I   V  +             +    +  G  +++  L A  + ++
Sbjct: 269 RSGQIAAQVASEHLSDGCD--LVEYQHRCKREIGDDLRASFLLARIMHRF 316


>UniRef50_Q3A4T4 Dehydrogenase, flavoprotein containing n=1 Tax=Pelobacter
           carbinolicus DSM 2380 RepID=Q3A4T4_PELCD
          Length = 384

 Score =  189 bits (480), Expect = 2e-46,   Method: Composition-based stats.
 Identities = 72/354 (20%), Positives = 110/354 (31%), Gaps = 25/354 (7%)

Query: 4   FDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +DVA++G GPAG+  A  LA   + V  LDK          K CGG L   A        
Sbjct: 6   YDVAVVGGGPAGTMAAIGLAKRGIDVCILDKAE----HPRYKVCGGGLLHRAAERL-PIS 60

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLI-PASVEVYHDS 121
                +V       +         + R++      + R   D  +               
Sbjct: 61  PEPFTEVACRNVELNFGGRQEGFVVRRDFPVV-RMVMRADLDAALWEEAGRCGAHCLSGP 119

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWF 181
               +    D   +          + AR++VGADG NS+V R            A++   
Sbjct: 120 KVCDLETSSDSVLLKT----DRGEVRARFVVGADGVNSVVARRGGWSPSPLAIAALECEL 175

Query: 182 AEKHPVPFYSC----IFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAF 237
           A         C       +     YSW   K  +   G    ++        L+    A+
Sbjct: 176 AVDDGTYGRFCDAARFDIDHPRRGYSWIFPKKNHLSVGLCSMVR--PVSGKGLRADFHAY 233

Query: 238 QFQFG--KTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDI 295
               G       E    L P   +          L G+AAG     + EG++ AL+S  +
Sbjct: 234 LKNQGIVPKEPGEIHAALIPVFPRLGQLADKGILLTGDAAGLADPLTAEGLTAALESGRL 293

Query: 296 LRSVLLKQP---EKLNTAYWRATRKLRLKLFGKIVKSRCLTA--PALRKWIMRS 344
               + +     EK+   Y +   +  L       K   L    P LR  I R 
Sbjct: 294 AAGAIAEGEMKREKVQAIYRQKLAEGLLADIEVSRKLAVLLYHHPHLRNLIFRF 347


>UniRef50_A8JAG1 Predicted protein n=1 Tax=Chlamydomonas reinhardtii
           RepID=A8JAG1_CHLRE
          Length = 494

 Score =  188 bits (479), Expect = 2e-46,   Method: Composition-based stats.
 Identities = 59/374 (15%), Positives = 105/374 (28%), Gaps = 34/374 (9%)

Query: 4   FDVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +D  I+G GP+GS  A  ++    +V  L+K+    T    K CG  +   A R     G
Sbjct: 63  YDAVIVGAGPSGSVCAYYMSRGGAKVALLEKE----TFPRDKYCGDAVCTPAIRILEDMG 118

Query: 63  LTLPVDV------IANPQIFSVKTVDVAASLTRNYQRSYIN-INRHAFDLWMKS-LIPAS 114
           +   +               S                +    + R   D+ +      A 
Sbjct: 119 VLQELVANNEAHFADAGGFVSPNGTSYIGVSKAKLGEAACCAVKRINLDIRVAKNAARAG 178

Query: 115 VEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKY 174
            ++            D    +          +  R LV ADGA S +   L    +  K 
Sbjct: 179 ADLKEKFEVTGATF-DKAAGLWTVTSATGTVVRGRVLVCADGATSRLATKLGYCTEAPKG 237

Query: 175 VAIQQWFAEKHPVP--FYSCIFDNSITNCYSWSISK-DGYFIFGGAYPMKDGQTRFTTLK 231
           +  + +             C +       Y+      +    F         +     +K
Sbjct: 238 ICSRAFIEGGTHNTNFDGVCFYPKWSLPGYAAIFRHPNDELNFCYYLIPCGKEGYCGEVK 297

Query: 232 EKMSAFQF--------------QFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGF 277
           E   A                      ++  +   L            D+  +IG+AAG 
Sbjct: 298 ESDLARLHNDAIKADPFISKAIGPNAKIERMRAASLRLGGQGLKTTFDDHLLIIGDAAGH 357

Query: 278 ISASSLEGISYALDSTDILRSVLL--KQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAP 335
           I   + EGI  A+         LL  +     +    +       +L+G         A 
Sbjct: 358 IDPYTGEGIHTAMMGGKAAAESLLAMRSTGDFSKQSTKQYEAEWRRLYGHDFWMSKAFAE 417

Query: 336 ALRKW-IMRSGVAH 348
            + ++ I+   VA 
Sbjct: 418 VVYRFPILLDAVAS 431


>UniRef50_A3CSH0 Geranylgeranyl reductase n=1 Tax=Methanoculleus marisnigri JR1
           RepID=A3CSH0_METMJ
          Length = 403

 Score =  188 bits (479), Expect = 2e-46,   Method: Composition-based stats.
 Identities = 74/369 (20%), Positives = 116/369 (31%), Gaps = 44/369 (11%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
            +D  ++G GPAGS  A  LA     +AL ++    T   +K CGG L+    R   R  
Sbjct: 6   EYDAVVVGGGPAGSTAACLLAEAGHSVALLER---RTYPRNKVCGGCLSQKTVRFLDRVF 62

Query: 63  -LTLPVDVIANPQIFSV----KTVDVAASLTRNYQRSYININRHAFDLWMKS-LIPASVE 116
            L +P    A    F+       +     LT +         R  +D ++      A  E
Sbjct: 63  SLPVPALRQAGLLDFTGTGYALYIGSRRILTEDLDEPVYFTGRERYDAFLAKMAARAGAE 122

Query: 117 VYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYP----DHQIR 172
           V+  +    I                    +AR ++GADG +S VRR L        + +
Sbjct: 123 VHTGAEAAGIDHARRTVT-----TSDGDRYSARVIIGADGVHSRVRRTLPQSVVDRKRWQ 177

Query: 173 KYVAIQQWFAEKHPVPFYSCIFDNSIT----------------NCYSWSISKDGYFIFGG 216
             +      A            D  I                   Y W        I G 
Sbjct: 178 NNLGWTLELAIPRREAETLVNEDGPIRLDDGLATPHLILAACRWGYGWVFPNREAIIVGI 237

Query: 217 AYPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTV--LFPSRWQDFVCGKDNAFLIGEA 274
              +         L++   AF    G +  + +     L P          +   L+G+A
Sbjct: 238 GGLL---SANGGNLRDTFEAFLKSVGLSAFAARKPAGYLLPLGNYIPSPAHEGTVLVGDA 294

Query: 275 AGFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTA 334
            GF      EGI YA  + ++      +            T  LR +L  ++        
Sbjct: 295 GGFTGPLLGEGIFYAHRTAELAAHAADRHLTAGAPLAATYTALLRRRLIPELRA-----E 349

Query: 335 PALRKWIMR 343
            ALR ++ R
Sbjct: 350 TALRNFVYR 358


>UniRef50_B8GFT3 Geranylgeranyl reductase n=1 Tax=Methanosphaerula palustris E1-9c
           RepID=B8GFT3_METPE
          Length = 401

 Score =  188 bits (478), Expect = 3e-46,   Method: Composition-based stats.
 Identities = 73/359 (20%), Positives = 125/359 (34%), Gaps = 34/359 (9%)

Query: 5   DVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           DV ++G GPAG   A  LA    QV+ +DK     T    K C G L    +    R   
Sbjct: 13  DVVVVGAGPAGVTAAYLLAKDGHQVLLIDK----ATFPRKKLCAGCLTEKTRDLLSRTFG 68

Query: 64  TLPVDVIANPQIFSV-----KTVDVAASLTRNYQRSYININRHAFDLWMKSLIPA-SVEV 117
                +I    + +       +        RN    +  ++R A+D  + +      V V
Sbjct: 69  LTETYMIREGIVAATADHYQISCRREMICKRNTSIPFTFVDRTAYDAKLLAAAEEAGVTV 128

Query: 118 YHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHL--YPDHQIRKYV 175
                   +   D    ++   DG  + IT RYL+GADG NS VR      P+ + R + 
Sbjct: 129 ITGCEVTSV---DPLIGLVMTRDG--RTITGRYLIGADGVNSRVRHAFPITPEDKNRWFQ 183

Query: 176 AIQQWFAEKHPVPFYSCIFDNSITN-----------CYSWSISKDGYFIFGGAYPMKDGQ 224
            +      K P    +  F                  Y W+   +   I G     + G+
Sbjct: 184 NLASTVEIKVPRSRLAPPFSGIDHPILFFDLPGWKAGYGWAFPGEEEVILGIGGLKQGGE 243

Query: 225 TRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLE 284
            R   + +   A +         +   + + +  ++   G   A L+G+A GF+     E
Sbjct: 244 RRVAEIFKTCLAAKGLEDMVSHPQGWALPYGNFIRNPTFGV--ALLVGDAGGFVEPFLGE 301

Query: 285 GISYALDSTDILRSVLLKQPE---KLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKW 340
           GI YA  + ++  + + +           Y +  R L        ++ R L    + + 
Sbjct: 302 GIFYAHRTGELAAAAVHRALSEGGDAADHYQQLIRSLICPELKADLRGRNLLFHLVHRL 360


>UniRef50_C4RL56 Alkylhalidase cmlS n=1 Tax=Micromonospora sp. ATCC 39149
           RepID=C4RL56_9ACTO
          Length = 656

 Score =  188 bits (477), Expect = 4e-46,   Method: Composition-based stats.
 Identities = 55/360 (15%), Positives = 100/360 (27%), Gaps = 34/360 (9%)

Query: 6   VAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           VAIIG GPAG      L      V   ++          +  G  L P       R GL 
Sbjct: 92  VAIIGGGPAGCVAGLTLHKLGHDVTIYER----DRFPRYRI-GESLLPGTMSILNRLGLQ 146

Query: 65  LPVDVIANPQIFSVKTVDVAASLTRNYQRSY-----------ININRHAFDLWMK-SLIP 112
             +D     +  S   +         +  +            I + R  FD  +      
Sbjct: 147 ERIDAEDFVKKPSATFLWGQDQAPWTFSFAAPKVAPWVFDHAIQVKREVFDNLLLDEARS 206

Query: 113 ASVEVYHDSLCRKIWRED-DKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQI 171
             + V  ++    +     D   +  R DG    + + +++ A G+   + R L      
Sbjct: 207 RGIAVLEETPVTGVDLSGADGVALTIRQDGKATRVESDFVIDAGGSGGPLVRQLGVRRYD 266

Query: 172 RKY--VAIQQWFAEKHPVPFY--SCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRF 227
             Y   A+  +F  K P         +  +  + + W I   G     G    +      
Sbjct: 267 EFYKNFAVWSYFQRKDPFEGDLKGTTYSITFEDGWVWMIPMKGDLYSVGLVVDRTKSAEV 326

Query: 228 TTL---------KEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFI 278
             L           K              +   ++    +   V   D  FL G+AA F 
Sbjct: 327 RQLGADAFYRSTLAKCGKAMDLLAGAKMVDDVRIVHDWSYDTEVFSADRFFLCGDAACFT 386

Query: 279 SASSLEGISYALDSTDILRSVLLK--QPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPA 336
                +G+  A  S     + + +    +    A      +   + + +  +        
Sbjct: 387 DPLFSQGVHLASQSAVCAAAAIDRITHNKDETDAVHAWYNRTYREAYEQYHEFLASFYTF 446


>UniRef50_UPI0001744EC4 Putative Dehyrogenase n=1 Tax=Verrucomicrobium spinosum DSM 4136
           RepID=UPI0001744EC4
          Length = 423

 Score =  187 bits (476), Expect = 5e-46,   Method: Composition-based stats.
 Identities = 73/388 (18%), Positives = 130/388 (33%), Gaps = 45/388 (11%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           +DV IIG GPAGS+ A  LA   + + + +K +          G  L P  ++ +   G+
Sbjct: 11  WDVVIIGGGPAGSSAATTLAQAGRKVLVLEKEKFPRFHI----GESLLPYNRQVYEELGV 66

Query: 64  TLPVDVIANPQIFSVKTV--DVAASLTRNYQRS-------YININRHAFDLWMK-SLIPA 113
              +      +    + +  D    +  ++ +         + + R  FD  +       
Sbjct: 67  WEKISQAGFMRKKGAQFLLGDGTRKVRLDFSKGSFTEFPEAVQVERAKFDNILLTHSQEC 126

Query: 114 SVEVYHDSLCRKIWREDDKWHVIFR-ADGWEQHITARYLVGADGANSMVRRHLYPDHQ-- 170
             EV  +SL + +  + D   V +R  +G    + A++L+ A G ++             
Sbjct: 127 GAEVRQESLVQDLQVDADGVAVKYRDKEGASHQVKAKFLIDASGLSNFTANRENRRTYYA 186

Query: 171 IRKYVAIQQWFAEKH--PVPFYSCIFDNSITNCYSWSIS-KDGYFIFGGAYPMKDGQTRF 227
             K +AI   FA         Y  I      N + W I  +D     G      D Q   
Sbjct: 187 EHKKIAIFNHFAGVDMPQGEEYGDILVIRRNNSWFWMIPLEDDKVSVGLVMDRGDFQALG 246

Query: 228 TTLKEKMS-------AFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISA 280
              ++          A Q +F K        V     +++     D     G+A+GFI  
Sbjct: 247 QEPRQVFEEAVRTTPAVQERFTKVAPPASVHVATDFSYRNNSLVSDRVIRAGDASGFIDP 306

Query: 281 SSLEGISYALDSTDILRSVLLKQPE------KLNTAYWRATRKLRLKLFGKIVK------ 328
               G+  A  S      V  +  +          AY   TR    + +  I +      
Sbjct: 307 VFSSGVLLATTSGRQAGLVADEAIKLGESMTPAMQAYETDTRNRIGQYWQFIERFYTQPF 366

Query: 329 SRCLTAPALRKWIMR------SGVAHIP 350
           ++    P+ R  +M       +G   +P
Sbjct: 367 AQLFFQPSNRFKMMCSINAVLAGCTRLP 394


>UniRef50_Q6ALA8 Related to dehydrogenases (Flavoproteins) n=1 Tax=Desulfotalea
           psychrophila RepID=Q6ALA8_DESPS
          Length = 352

 Score =  187 bits (475), Expect = 6e-46,   Method: Composition-based stats.
 Identities = 67/327 (20%), Positives = 124/327 (37%), Gaps = 20/327 (6%)

Query: 1   MEHFDVAIIGLGPAGSALARKL-AGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           ME FD+ IIG GPAG A A++       V+ L++  Q G     K C G +  +     +
Sbjct: 1   MEFFDIVIIGAGPAGLACAKEAGKRGYSVLVLERNGQIGR----KVCAGGITWNGLMRHM 56

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYH 119
               T       +     + +   +  +  ++      +NR      M      +  V  
Sbjct: 57  PGFATERDFAKQH-----LFSRYQSCCIEADHPIVA-TLNREHLGRSMAEQAQEAGAVIR 110

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQ 179
            +  + +    +K  V  R  G +  +  +YLVGADG++S+VRR+L    +   ++ +  
Sbjct: 111 -TEEQALQIGAEKITVRERKTGRDYSVAFKYLVGADGSSSLVRRYLGQPVK---HIGLGL 166

Query: 180 WFAEKHPVPFYSCIF-DNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQ 238
            F  +            +   N Y+W          G            T LK +   + 
Sbjct: 167 NFQIRGRAEKMEWHLRPDLFVNGYAWIFPHQNTISIGAYADRSIFSP--TELKRRFLVWA 224

Query: 239 FQFGKTVKSEKC-TVLFPSRWQDFVCGKDN-AFLIGEAAGFISASSLEGISYALDSTDIL 296
              G  ++ E+C        ++ +  G DN  FL G+AAG  S  + EGI  A+ S   +
Sbjct: 225 KAQGYGLEQERCTAGYINYDYRGYRFGSDNNIFLTGDAAGLASGLTGEGIYPAIVSGIAV 284

Query: 297 RSVLLKQPEKLNTAYWRATRKLRLKLF 323
              +    +         +++++ ++ 
Sbjct: 285 AEEIAGCKDHPELEAVIKSQRMQRRIL 311


>UniRef50_Q0Q5F4 Halogenase n=8 Tax=Actinomycetales RepID=Q0Q5F4_9ACTO
          Length = 458

 Score =  187 bits (475), Expect = 6e-46,   Method: Composition-based stats.
 Identities = 54/348 (15%), Positives = 106/348 (30%), Gaps = 30/348 (8%)

Query: 6   VAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTL 65
           V +IG GPAGS  A  LA +   + L ++            G  + P  +  F   G+  
Sbjct: 7   VLVIGGGPAGSTAAGLLARQGVQVTLLERETFPRYHI----GESILPSCRPIFELLGVWD 62

Query: 66  PVDVIANPQIFSVKTVDVAASLTRNY------QRSYININRHAFDLWMKSLIPA-SVEVY 118
            V+                      +        +   + R  FD  +        V+V+
Sbjct: 63  KVEAFGFQPKGGAYFSWGPDEWEVRFAELGADGANAWQVTRADFDKLLLDHSRELGVDVH 122

Query: 119 HDSLCRKIWREDDK-WHVIFRADGWEQHITARYLVGADGANSMVR-RHLYPD--HQIRKY 174
                ++I  + D+     +  DG    +T  YL+ A G   ++  ++L     H + + 
Sbjct: 123 EGVTVKEIEFDGDRPVAARWAGDGKTGRLTFDYLIDASGRRGVMATKYLGARTFHSVFRN 182

Query: 175 VAIQQWFAEKHPVPFYSC--IFDNSITNCYSWSIS-KDGYFIFGGAYPMKDG-------- 223
           VA   ++    P+       I   S+   + W+I   DG    G                
Sbjct: 183 VATWSYWKNAKPLDRGPAGSITVASVPEGWFWAIPLHDGTTSVGLVTGRDTFNRRRREQG 242

Query: 224 --QTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISAS 281
             +  +     +    Q       +           +           L G+AA F+   
Sbjct: 243 GIEAVYDDALRQCPLVQELLADAERVSDFKTEQDYSYTSETFHGPGYLLCGDAACFLDPL 302

Query: 282 SLEGISYALDSTDILRSVLLK--QPEKLNTAYWRATRKLRLKLFGKIV 327
              G+  A  S  +  + +    + E   +  W     +    + +++
Sbjct: 303 LSTGVHLATYSAMLAAASIGSVLRGEVEESEAWAFFDGVYRSSYERLL 350


>UniRef50_Q2S264 FAD dependent oxidoreductase, putative n=1 Tax=Salinibacter ruber
           DSM 13855 RepID=Q2S264_SALRD
          Length = 385

 Score =  187 bits (475), Expect = 6e-46,   Method: Composition-based stats.
 Identities = 75/375 (20%), Positives = 130/375 (34%), Gaps = 40/375 (10%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           +D  +IG G +G + A +LA +   + L    +  T    K CG  L+P+AQ SF R G+
Sbjct: 3   YDALVIGGGLSGCSTALQLAREGHDVLL---AEQSTYPRQKLCGEFLSPEAQSSFRRLGV 59

Query: 64  TLPVDVIAN-PQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKS-LIPASVEVYHDS 121
              V      P   +  T    A+ + +   + +  +R+  D  +        VE    +
Sbjct: 60  LDDVRAAGAEPIGRTCLTTSSGATTSHSLPDAALGFSRYRLDQLLFQKACTMGVEGRSGT 119

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDH--QIRKYVAIQQ 179
               I          F A      + AR ++GA G  S + R L      +   YVA + 
Sbjct: 120 RVTNIR---GGLRDGFVASVGGDSVEARLVLGAHGRRSRLDRSLERPFLSENTPYVAFKA 176

Query: 180 WFAEKHPVPFYSCIFDNSITNCYSWSIS-KDGYFIFGGAYPMKDGQTRF--------TTL 230
            +A        + I  +S    Y      +               +           TTL
Sbjct: 177 HYAGPTAAALENTIELHSAPGAYCGLSPVEGNRINVCWIGRTDALKDAGGSPEGMLNTTL 236

Query: 231 KEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYAL 290
           ++  +  +   G T  S++   +            D+  +IG+AAG I+    +G++ AL
Sbjct: 237 RQNPAFDERLSGLTRVSDRFEAVSQVPLMPKSRFADDVCMIGDAAGMIAPLCGDGMAMAL 296

Query: 291 DSTDILRSVL---------LKQPEKLNTAYWRATRKLRLKLFGKIVKSRC---------- 331
            + D++  +                     W  T   R++L   I  +            
Sbjct: 297 RTADLVSPLASDFLNGRHPAHAFRTSYETAWTDTFGQRMRLGRWIHAAAFRPGAAWTLVQ 356

Query: 332 --LTAPALRKWIMRS 344
                P L +WI+RS
Sbjct: 357 SCRLLPPLAQWIIRS 371


>UniRef50_A7BBW6 Putative uncharacterized protein n=1 Tax=Actinomyces odontolyticus
           ATCC 17982 RepID=A7BBW6_9ACTO
          Length = 422

 Score =  186 bits (474), Expect = 8e-46,   Method: Composition-based stats.
 Identities = 52/362 (14%), Positives = 102/362 (28%), Gaps = 38/362 (10%)

Query: 16  SALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTL--PVDVIAN 72
           S+ A  LA   + V+ L+K          K CG  L P A    I  G+     +     
Sbjct: 19  SSTAYHLARVGLDVVLLEKSP----FPRDKICGDGLTPAAVHELIAMGVDTTGWMRNRGL 74

Query: 73  PQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLI-PASVEVYHDSLCRKIWREDD 131
             I    TV +     ++     +   R   D  +      A   +Y         ++  
Sbjct: 75  TVIGGGHTVHMDWPDQKSLPGYGMTRARMDLDHTLARRAVEAGARLYEGVTVIGAIQDGS 134

Query: 132 KWHVIFRADGWEQ------HITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEKH 185
              V  +             + A  +V A G  + +   L  + ++ + + +        
Sbjct: 135 GRVVGVQVKSGRGKNAATFEVRASIVVDAGGVAARLATSLGLEKKMNRPMGVAARAYFHS 194

Query: 186 PVPFYSCIFDN-----------SITNCYSWSIS-KDGYFIFGGAYPMKDG----QTRFTT 229
           P      +  +            +   Y W     DG    G                  
Sbjct: 195 PRGDEEWMESHLELWSGTPGASDLLPGYGWIFPMGDGIVNVGLGSVASRAGATNLPYREV 254

Query: 230 LKEKMSAFQFQFGKTVKSEKC---TVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGI 286
            K   +    ++G T +++     +   P  +           L+G+A G +S  + EGI
Sbjct: 255 FKTWTANLPEEWGFTPENQIGQLRSAALPMSFNRKPHYTQGLVLVGDAGGMVSPYNGEGI 314

Query: 287 SYALDSTDILRSVLLKQP----EKLNTAYWRATRKLRLKLFGKIVKSRCLTAPAL-RKWI 341
           + A+ +     S + +                   +    +G   +   +    +    I
Sbjct: 315 APAMKAGRYAASCIAQALSRSHRAGIDRAMSEYPHMLRDEYGGYYQLGRIFVALIENPAI 374

Query: 342 MR 343
           MR
Sbjct: 375 MR 376


>UniRef50_Q9U641 Conditioned medium factor receptor 1 n=1 Tax=Dictyostelium
           discoideum RepID=CMFB_DICDI
          Length = 510

 Score =  186 bits (473), Expect = 1e-45,   Method: Composition-based stats.
 Identities = 67/374 (17%), Positives = 128/374 (34%), Gaps = 36/374 (9%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQ-VIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +DVA IG GP+GS L   LA + + V  L+KK         K CG  +A  AQ      G
Sbjct: 81  YDVATIGAGPSGSVLGYYLAREGRKVALLEKK----VFPRDKYCGDAVATMAQDILREMG 136

Query: 63  L---TLPVDVIANPQIFSVKTVDVAASLT---------RNYQRSYIN-INRHAFDLWMKS 109
           +    +  D+    Q     + +  + +            Y R  +  + R   D  +  
Sbjct: 137 VMKELVDEDLGHFAQNGGFVSPNGNSFIGNSAKELKRDAKYNRGAVIAVKRIVLDEKVAK 196

Query: 110 LIPA-SVEVYHDSLCRKIWRED--DKWH---VIFRADGWEQHITARYLVGADGANSMVRR 163
                  ++  ++       +     W    V    +  +    AR LV ADG+ S   R
Sbjct: 197 AAKRMGADLKENTTVENATFDRSTGVWTINCVDSEDNTKKIVYRARVLVCADGSPSNAAR 256

Query: 164 HLYPDHQIRKYVAIQQWFAEKHPVPFY-SCIFDNSITNCYSWSISKDGYFIFGGAYPMKD 222
            L   H     +  + +        +     +  S+   Y   I +    +   AY +  
Sbjct: 257 QLGYVHTEPNGICSRAYVKNNTTFRYDGVVFYPPSLLPGYCAIIREARDELNYLAYIIPG 316

Query: 223 GQTRFTTLKEKMSAF-------QFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAA 275
           G+     L +    +           G     E+                D+  ++G+AA
Sbjct: 317 GKVTNDDLSKYHHQYMTEDPFISAALGPNPDIERMKAAPLRLGGIKKSYDDHLLIVGDAA 376

Query: 276 GFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYW--RATRKLRLKLFGKIVKSRCLT 333
           GFI   + EGI YA++ + +    L++   + + ++   +  +   +  FG         
Sbjct: 377 GFIDPLTGEGIQYAMEGSRLASLALIQAFNERDLSHQSLKRYQDFWMAKFGHEFSMSMTM 436

Query: 334 APALRKW--IMRSG 345
           +  L ++  ++ + 
Sbjct: 437 SLFLYRFPIVLDAA 450


>UniRef50_C6XUK6 FAD dependent oxidoreductase n=1 Tax=Pedobacter heparinus DSM 2366
           RepID=C6XUK6_PEDHD
          Length = 378

 Score =  186 bits (473), Expect = 1e-45,   Method: Composition-based stats.
 Identities = 48/352 (13%), Positives = 107/352 (30%), Gaps = 23/352 (6%)

Query: 6   VAIIGLGPAGSALARKL-AGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           + I+G G +G   A  L     +V  ++K          K CG  ++ +           
Sbjct: 11  ILIVGGGLSGLTCALHLLKEGFEVTLIEK----NAYPHHKVCGEYISNEVLPYLQWLDAD 66

Query: 65  LPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLCR 124
            P +++         +      +          ++R A D ++     +           
Sbjct: 67  -PYELLPVAINRLSVSSLSGQIIGCALPLGGFGLSRFALDHFLYQKALSRGCKVIRDRVT 125

Query: 125 KIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDH--QIRKYVAIQQWFA 182
            I    +++ +     G    + A  ++GA G  S + + L      +   ++A++  + 
Sbjct: 126 DIVFNGNEFELSTSHSG---TLKADLVIGAFGKRSALDQQLSRSFIQKKSPWLAVKAHYN 182

Query: 183 EKHPVPFYSCIFDNSITNCYSWSISKDGY-FIFGGAYPMKDGQT--RFTTLKEKMSAFQF 239
              P+        ++    Y    + +            +  +        +EK+     
Sbjct: 183 GIIPIDLVQL---HNFAGGYCGVSAIENKQINICYLADYESFKACANLKDFQEKVLYKNP 239

Query: 240 QFGKTVKSEKCTVLFP-----SRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTD 294
           Q  K  +        P       +       D+  +IG+ AG I      G++ A+ S  
Sbjct: 240 QLRKIFEESSPVFDQPLTISQVSFAKKELVCDHILMIGDTAGLIHPLCGNGMAMAIHSAK 299

Query: 295 ILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGV 346
           I   + ++       +      KL    +    K+R L    L   I +  +
Sbjct: 300 ICAELSIQYLNGKLVS-RTTLEKLYTATWNANFKNRLLMGRFLSGIIRKDKL 350


>UniRef50_A0M1U0 Oxidoreductase n=2 Tax=Flavobacteriaceae RepID=A0M1U0_GRAFK
          Length = 377

 Score =  186 bits (473), Expect = 1e-45,   Method: Composition-based stats.
 Identities = 65/374 (17%), Positives = 135/374 (36%), Gaps = 34/374 (9%)

Query: 1   MEHFDVAIIGLGPAGSALARKL-AGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M++  V IIG G AG   A  L   ++ VI ++K+         K CG  L+ +      
Sbjct: 1   MKNTQVIIIGGGLAGLTAAIHLCQKEIDVILIEKEQ----YPHHKVCGEYLSREVIPYLN 56

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTR-NYQRSYININRHAFDLWMKSLIPASVEVY 118
              L +  + +  P I  V+   V+  L   +     I I+R++ D  +      S    
Sbjct: 57  SLNLNI--EALKAPIINRVEYSSVSGKLISCDLNMGGIGISRYSLDHLLYKKAENSGCTI 114

Query: 119 HDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDH--QIRKYVA 176
            +SL  +I   ++++ V        + IT+ +++GA G  S + + L      +   ++A
Sbjct: 115 INSLAVEIEYTNEQFIVTTSQG---EIITSEFVLGAYGKRSNLDKKLSRKFIQEQSGWLA 171

Query: 177 IQQWFAEKHPVPFYSCIFDNSITNCY-SWSISKDGYFIFGGAYPM------KDGQTRFTT 229
           ++  +         + +  ++ +  Y   S ++                  K+ +     
Sbjct: 172 VKAHYKTNSEFYSENLVSLHNFSGGYCGLSKTELNTINVCYLASYASFKNYKNTEDYKEK 231

Query: 230 LKEKMSAFQFQFGKTVKSEKCTVLFP-SRWQDFVCGKDNAFLIGEAAGFISASSLEGISY 288
           +  K    +  F          +      +      +++  +IG++AG I      G++ 
Sbjct: 232 VLMKNPHLRKFFNNAEMVFDKELSIAQVCFDKKSMIENHILMIGDSAGLIHPLCGNGMAM 291

Query: 289 ALDSTDILRSVLLK-------QPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKW- 340
           A+ S  I    +L+           +   Y +   +   K   ++   R L    L K  
Sbjct: 292 AIHSAKIASEGILRFYNLKNITRNDVENNYVQEWNQ---KFSSRLKAGRVLQKVFLNKTL 348

Query: 341 --IMRSGVAHIPQL 352
             I +  +  +PQL
Sbjct: 349 TNISQGFLNRVPQL 362


>UniRef50_B4CVZ2 Geranylgeranyl reductase n=1 Tax=Chthoniobacter flavus Ellin428
           RepID=B4CVZ2_9BACT
          Length = 357

 Score =  185 bits (470), Expect = 2e-45,   Method: Composition-based stats.
 Identities = 69/349 (19%), Positives = 108/349 (30%), Gaps = 27/349 (7%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
            +DVAIIG GPAGS  A   A       + +K         K CG  + P       R G
Sbjct: 2   EYDVAIIGAGPAGSTCAAHCAQAGWRTLVIEKA---RFPRDKVCGDCVNPACWPILDRLG 58

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTR----NYQRSYININRHAFDLWMKSLIPA-SVEV 117
           +T  +    + ++  V  V       R    +  R  I I R  FD  +         EV
Sbjct: 59  VTDRLHAQPHSRLKEVAFVSPQGRTLRLPLPDSDRGEIAIPRRLFDAVLLDRARELGAEV 118

Query: 118 YHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYP-DHQIRKYVA 176
           + D+    +      W +           +ARYL+ ADG NS V R L       +  + 
Sbjct: 119 HEDAPLTALE---SGWKLQTTRG----SFSARYLIAADGRNSTVARLLGLLPAAAKDRIG 171

Query: 177 IQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSA 236
           +Q        +     +           +   +  F        +            + A
Sbjct: 172 LQAHLPIPSGMHERVAMHFLPF-GYCGMNDIGNEQFNLCLVARPER--------LADLKA 222

Query: 237 FQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDIL 296
           +               + P          +    IG+AA  +   + EGI YAL S ++ 
Sbjct: 223 WAAARFDIAPETAWRTITPLSRAPIGTVHERLLAIGDAARIVEPFTGEGIYYALASGELA 282

Query: 297 RSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSG 345
              LL        A        R +L+   +    +  P L   I+   
Sbjct: 283 ARHLLANDLPGFAAAHARLY--RGRLWVNELARAAVLRPWLATGILEFA 329


>UniRef50_A8LAV2 Geranylgeranyl reductase n=5 Tax=Actinomycetales RepID=A8LAV2_FRASN
          Length = 409

 Score =  185 bits (470), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 75/356 (21%), Positives = 120/356 (33%), Gaps = 20/356 (5%)

Query: 5   DVAIIGLGPAGSALARK---LAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
           D+ ++G GPAGS+ A +   L    +V+ +D           K CG  +AP         
Sbjct: 23  DLLVVGGGPAGSSAALRALQLRPDARVVIVD----AADFPRDKTCGDGIAPHGVDVLRAL 78

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDS 121
           G+T        P           A +    +R+   I R  FD  + +   A    +   
Sbjct: 79  GITDATSGY-RPVDRMRLRTPGGAEVATPSERATHVIPREVFDARLVAAARARGAEFLRR 137

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLY--PDHQIRKYVAIQQ 179
             R +                   + AR +VGADGANS VRR L   P+      +A++ 
Sbjct: 138 RVRSLEVTAGG-GGEPVVTVDGGVLRARVVVGADGANSTVRRALGIAPNPPEGLAIAVRA 196

Query: 180 WFAEKHPVPFYSCIFDNSITNC--YSWSIS-KDGYFIFGGAYPMKDGQTRFTTLKEKMSA 236
           +            + + +      Y+WS    DG    G        +   TT K  +  
Sbjct: 197 YADAPKDDRPPEQLIEMTDEGWPAYAWSFPIGDGRANIGYGMLRSRLRAAGTTPKAVLHG 256

Query: 237 FQFQFGKTVKSEKC---TVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDST 293
              +      + +        P              L G+AA  I+  + EGI YAL S 
Sbjct: 257 TLARLLPDTPAYEGTLRAHHLPLSTHRPRLPDGPVLLAGDAASLINPLTGEGIYYALLSG 316

Query: 294 DILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALR-KWIMRSGVAH 348
            +     +  P       +R  R L  +L   +  +  L   A R + +M + V  
Sbjct: 317 SLAGQAAITDPGPAAGRAYR--RALDGELGRHLRHTSLLAGLAGRHRPLMDAAVRS 370


>UniRef50_C9RKL4 FAD dependent oxidoreductase n=1 Tax=Fibrobacter succinogenes
           subsp. succinogenes S85 RepID=C9RKL4_FIBSS
          Length = 398

 Score =  184 bits (469), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 60/355 (16%), Positives = 108/355 (30%), Gaps = 26/355 (7%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG--KMQ-VIALDKKHQCGTEGFSKPCGGLLAPDAQRSF 58
             + V I G GPAG   A +L         I L  K +   E     C   ++       
Sbjct: 7   NSYKVVICGAGPAGLMAAYQLGKLTGGDGQILLLDKKEPWKEPIF--CAEAVSTHRLNEL 64

Query: 59  IRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSL-IPASVEV 117
                +     ++     S K            +     ++R  F   +    + + VE 
Sbjct: 65  WPIDESWVRGSLSGIYFTSPK----GYKAEFYSKDCGRLLDRSKFHHAIADACVESGVEC 120

Query: 118 YHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHL--------YPDH 169
             D+L + I + ++ W++  +       ++A   + A G    + R +            
Sbjct: 121 RFDALVKSIEKTENGWNLNVQVGKEFFSLSADAFIDASGPGCRLTRGIPCLEGIESGDTD 180

Query: 170 QIRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTT 229
                 A+ +    +H       ++ +     Y W   +DG  +  G    KD +     
Sbjct: 181 LEPGIFAVAE--GIEHDRDHIDLLYGSEFPGGYGWIFPRDGKEVNVGFVLSKDAKPDMP- 237

Query: 230 LKEKMSAF-QFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISY 288
           L+EK+  F    +           +      D    K   F  G+AA  ++  S  GI  
Sbjct: 238 LREKLKHFIATHYPNAKVKAIYGGMIACGQSDKPLAKCGLFKAGDAASCVNPLSRSGIVE 297

Query: 289 ALDSTDILRSVLLKQPEKLNTAYWRATR----KLRLKLFGKIVKSRCLTAPALRK 339
           AL S  I+   + +     + A             +   GK         P L K
Sbjct: 298 ALLSGKIVAEAVHEWLNASDDAARSRIEASVLDRWMAKLGKSHLQIARAKPGLAK 352


>UniRef50_UPI0000D53425 oxidoreductase n=1 Tax=Psychroflexus torquis ATCC 700755
           RepID=UPI0000D53425
          Length = 310

 Score =  184 bits (469), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 69/322 (21%), Positives = 123/322 (38%), Gaps = 28/322 (8%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPD-AQRSFIR 60
            +DV +IG GPAGS +AR  A    +V+ +D +   GT      CG L+  +   R    
Sbjct: 6   DYDVIVIGGGPAGSTVARYAAEGGIRVLVMDARKSIGT---PLQCGELVPTNDEMRRLCP 62

Query: 61  DGLTL------PVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLI-PA 113
           D   +      P + I+              SL+  ++   + +NR   D  + SL   A
Sbjct: 63  DVPDMDDLFQTPDEAISRKCDTMNIITPSGKSLSYRFE--GLILNRVTHDEALVSLAKEA 120

Query: 114 SVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRK 173
             E   +S  +++        V  R     +  TA+ +VGA G    VRR  + +  +  
Sbjct: 121 GAEYLVNSFVKEVNEN----TVTTR---DGETYTAKVIVGAGGHKDPVRRKYWREKTVN- 172

Query: 174 YVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEK 233
            + ++    +          F +     Y+W   K      G     +    +  +LKE 
Sbjct: 173 -IPVKFELKDGDYGEAVELHFGSMAPGGYAWMFPKSVGANIGLGI--QKNFAKGKSLKEY 229

Query: 234 MSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDST 293
            +AF  ++ +   + K     P         K+N  L+G++AG +  S+  GI+ A+   
Sbjct: 230 STAFIDKY-EGESTFKGGGSLPMSGTIKRFVKENYVLVGDSAGMVLPSNGAGITIAMVGG 288

Query: 294 DILRSVLLKQP--EKLNTAYWR 313
            I    + +     +  T Y +
Sbjct: 289 RIAGQAIARHILEGEPLTNYEK 310


>UniRef50_B9M019 FAD dependent oxidoreductase n=1 Tax=Geobacter sp. FRC-32
           RepID=B9M019_GEOSF
          Length = 353

 Score =  184 bits (468), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 78/356 (21%), Positives = 125/356 (35%), Gaps = 38/356 (10%)

Query: 1   MEHFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M+ +DV I G GPAGS  A+ L      V+ L+K+         K C G+L    Q    
Sbjct: 1   MQQYDVVIAGSGPAGSTCAKALKDEGFSVLVLEKEIL----PRHKTCSGVLFGQTQELIR 56

Query: 60  RD-GLTLPVDVIANPQIFSVKTVDVAASL-------------TRNYQRSYININRHAFDL 105
              G  +P +V    +      +                    R + R+Y NI R  FD 
Sbjct: 57  AYFGTHVPAEVYCGNKFVEADDIREWDDEQGYIPYTWEIDKDGRKFSRTYHNIWRDKFDK 116

Query: 106 WMKSLIPASVEVYHDSLCRKIWREDDK--WHVIFRADGWEQHITARYLVGADGANSMVRR 163
           W+     +  E    +  +           HV              Y VGADG +S VRR
Sbjct: 117 WLLD--QSGAEYRDGAKVKAFDAGGSTVDVHVHMSRTNESAVFKCEYFVGADGNDSTVRR 174

Query: 164 HLYPDHQI----RKYVAIQQWFAEKHPVP----FYSCIFDNSITNCYSWSISKDGYFIF- 214
            L+  +       K  + Q ++  K         ++      I +       KD Y +  
Sbjct: 175 LLHAQNPEYAQRHKLASYQSYYKVKSLGSLKPNGWTVFLRQEIGDYILCVHQKDEYLVMH 234

Query: 215 GGAYPMKDGQTRFTTLKEKMS-AFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGE 273
            G    ++ +      KE +S  F   FG+  + E CT      +     G++   + GE
Sbjct: 235 VGGMDGRNLRQSMEKFKELLSGRFGVSFGEHWRDEGCTCELLPIF----LGQEKVLVTGE 290

Query: 274 AAGFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKS 329
           AAGFI   + EGIS A+DS       + +      ++      +    +   + + 
Sbjct: 291 AAGFIY-LNCEGISAAMDSGYRCGKAIAQALRSNGSSARDLYGEACRDILQHMDRC 345


>UniRef50_D1UBF5 Geranylgeranyl reductase n=1 Tax=Desulfovibrio aespoeensis Aspo-2
           RepID=D1UBF5_9DELT
          Length = 396

 Score =  184 bits (468), Expect = 4e-45,   Method: Composition-based stats.
 Identities = 70/351 (19%), Positives = 108/351 (30%), Gaps = 20/351 (5%)

Query: 2   EHFDVAIIGLGPAGSALARKL-AGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           +  DV I G GPAG+     L      V+ LDK          K CGGLL   + R    
Sbjct: 3   KRHDVIICGCGPAGATAGLALARRGHSVLMLDK----ARFPRPKLCGGLLTWKSVRLLET 58

Query: 61  DG-----LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFD-LWMKSLIPAS 114
                        VI +           +   +      +  I+R   D   +     A 
Sbjct: 59  VFHESVPGLTEAGVITHVSDRYTIRTPASLLTSGAMPYPFHFIDRSRLDARLLDHAARAG 118

Query: 115 VEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRK- 173
            +V   +                        + A +L+GADGANS+VR       + R  
Sbjct: 119 AKVMLGARVTACDPGGGSTPARLTLADGT-VLEADHLIGADGANSVVRNSFLGHDRDRFN 177

Query: 174 ---YVAIQQWFAEKHPVPFYSC--IFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFT 228
                AI+             C  ++   I   Y W        + G     + G+ +F+
Sbjct: 178 QFMAPAIEVTLDPAALPEPVECPELYVGFIEAGYGWVFPGQDRVLVGLCGLRR-GKVKFS 236

Query: 229 TLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISY 288
            L      F     + V   +     P           +A L+G+A GF+     EGI Y
Sbjct: 237 NLFRDFLDFLKIDSRAVPPLRG-HPLPYGNALENPVCGHAMLVGDAGGFVEPLFGEGIFY 295

Query: 289 ALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRK 339
           A+ +       +    E         T +LR  +  ++  S  L     R 
Sbjct: 296 AMCTGLYAGEAVASALEDGQAPGPLYTARLRRDISPELRGSDRLRWLLFRA 346


>UniRef50_B4UA54 Geranylgeranyl reductase n=1 Tax=Hydrogenobaculum sp. Y04AAS1
           RepID=B4UA54_HYDS0
          Length = 376

 Score =  184 bits (468), Expect = 4e-45,   Method: Composition-based stats.
 Identities = 59/337 (17%), Positives = 109/337 (32%), Gaps = 41/337 (12%)

Query: 1   MEHFDVAIIGLGPAGSAL---------ARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLL 50
           ME +DV +I                  + +LA    +V+ ++K          K C G +
Sbjct: 1   MERYDVIVI---------GGGPAGAGASYELADAGAKVLVIEKAK----YPRPKLCAGCI 47

Query: 51  APDAQRSFIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSL 110
           +  +   F       P   I N     +        + +      + ++R  FD ++ S 
Sbjct: 48  SKRSVDLF-------PAFNIKNSIKGGILGFKGQEFVEKVSDECAVIVDREEFDHFLISK 100

Query: 111 I-PASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDH 169
                  +  +   + I        VI      +    A Y++GADG +S+ R+ +    
Sbjct: 101 AQEKGAHLLEEITAKDIELTPTVRKVIT----DKGVFEADYVIGADGYHSITRKSIACKS 156

Query: 170 QIRKYVAIQQWFAEKHPV-----PFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQ 224
             RK+  I         +          I    +   Y W   +  +   G A   K+  
Sbjct: 157 ASRKFF-IAMEVKVPKDMFKDFKEDEVLIDIGVVKKGYGWYFPQGEFVNIGIATAEKEDL 215

Query: 225 TRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLE 284
                   K            + +   + F S+ Q+   G+D  FL G+A   +     E
Sbjct: 216 LNIFKAYTKNHKLFPIDISKYRIKSWFIPFISKAQELRLGRDRVFLTGDAGAIVDPLLGE 275

Query: 285 GISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLK 321
           GI YA  S  +    +    +  ++ Y R  +   L+
Sbjct: 276 GIRYAYLSGSLCARAIKLAKKDAHSLYERFVKNTILE 312


>UniRef50_Q3A9B4 FixC protein n=1 Tax=Carboxydothermus hydrogenoformans Z-2901
           RepID=Q3A9B4_CARHZ
          Length = 431

 Score =  184 bits (467), Expect = 5e-45,   Method: Composition-based stats.
 Identities = 61/357 (17%), Positives = 123/357 (34%), Gaps = 42/357 (11%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPD-AQRSFI 59
           E FDV ++G GP+G A A KLA   ++VI +++    G +      GG++     +  F 
Sbjct: 3   EKFDVVVVGAGPSGLAAAYKLAEAGLKVIVIERGEFPGAKN---VMGGIIYKKPTEAVFP 59

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQR-----SYININRHAFDLWMKSLI-PA 113
                 PV+     Q +   T       +    R     S  ++ R  FD ++   +   
Sbjct: 60  EIFKEAPVERPIIEQRYYFLTDTAKIGFSYRNPRYKEDISGYSVFRAKFDRFLAKKVQEK 119

Query: 114 SVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRK 173
              +  +++   +  +D K   +  A   E  + A  +V A+GA+S++ +       I  
Sbjct: 120 GALLITETVVEDLIVKDGKVKGVI-AGRKEGEVLADVVVLAEGAHSLLAQKYGFQKPIPP 178

Query: 174 ---YVAIQQWFAEKH----------PVPFYSCIFDNSITNCY---SWSISKDGYFIFGGA 217
               VA+++                P    +       T      ++  +       G  
Sbjct: 179 QNLAVAVKEVIGLPASVIEDRFNIEPGEGVAIELFGKATAGMVGTAFIYTNQNSLSIGVG 238

Query: 218 YPMKDGQTRFTTLKEKMSAF------QFQFGKTVKSEKCTVLFPSRWQD--FVCGKDNAF 269
             M D   R  +  + + AF      +         E    L P            D   
Sbjct: 239 ALMSDLIKRRISPNDLIEAFKNHPAIKPLLRDGEVKEYLAHLIPEGGYKGIPKLYGDGIV 298

Query: 270 LIGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKLNTA------YWRATRKLRL 320
           ++G+A   +++   EG + A+ S  +    +++   + + +      Y    R+  +
Sbjct: 299 IVGDAGMLVNSIHREGSNLAITSGALAAKAIIRAASQGDFSANTLKVYEDYLRESFV 355


>UniRef50_A3XIL9 Putative uncharacterized protein n=1 Tax=Leeuwenhoekiella
           blandensis MED217 RepID=A3XIL9_9FLAO
          Length = 374

 Score =  183 bits (464), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 57/356 (16%), Positives = 116/356 (32%), Gaps = 36/356 (10%)

Query: 6   VAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           +A+IG G AG   A  L     QV+  +K+         K CG  L+ +    +   G+ 
Sbjct: 7   IAVIGAGLAGLTAAIHLRKEGFQVMLFEKEE----YPKHKVCGEYLSNEILPYWKHLGID 62

Query: 65  LPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLCR 124
            P+   A        +     SL          I+R   D  +     +          R
Sbjct: 63  -PLKWGAVAIDQLELSAVNGKSLNIKLPLGGFGISRFKLDHHLLEYALSLGCTLISQTVR 121

Query: 125 KIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQ--IRKYVAIQQWFA 182
            I   ++ + +  +     Q   A  ++GA G  S +   L          ++A++  FA
Sbjct: 122 DIHFAENTFSISTK---EHQDFEADLVIGAFGKRSNIDFKLDRKFTASKNDWLAVKAHFA 178

Query: 183 EKHPVPFYSCIFDNSITNCY-SWSISKDGYFIFGGAYPMKDGQT-------------RFT 228
            + P    S    ++    Y   S+ ++           +  +                 
Sbjct: 179 AEIPSDQVSL---HNFKGGYCGISMVEERKVNVCYLTRTEAFKPFKNNETFQQQVLCENP 235

Query: 229 TLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISY 288
            L +  +  Q  F + +   +        +Q     +++  + G++AG I      G++ 
Sbjct: 236 NLNDFFAHAQPLFDQPISISQIA------FQSKPSVENHMLMCGDSAGLIHPLCGNGMAM 289

Query: 289 ALDSTDILRSVLLKQPEKL--NTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIM 342
           A+ S  +    +     +    T   +   KL  + F   +++  L   AL+   +
Sbjct: 290 AVISAKLASECISGSARQDWSRTELEQRYDKLWKQTFTNRLRAGNLLQRALQNDAL 345


>UniRef50_B9XPY2 Tryptophan halogenase n=3 Tax=Verrucomicrobiales RepID=B9XPY2_9BACT
          Length = 424

 Score =  182 bits (463), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 53/363 (14%), Positives = 105/363 (28%), Gaps = 33/363 (9%)

Query: 1   ME-HFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M+  +DV +IG GPAGS+ A  LA K   + + ++ +          G  L P       
Sbjct: 1   MKTDYDVIVIGGGPAGSSAAAILAEKGHKVLVLEREKFPRYHV----GESLLPFTFHPLQ 56

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQR---------SYININRHAFDLW-MKS 109
           R GL   +      + FSV+ V  +   ++ +               + R  FD   +  
Sbjct: 57  RLGLVEKLRASQFVKKFSVQFVSPSGRASQPFYFFNRYDKDVAQTWQVLRSEFDQIVLDH 116

Query: 110 LIPASVEVYHDSLCRKIWREDDKWHVIFRAD--GWEQHITARYLVGADGANSM--VRRHL 165
                  V  +    ++ ++ D+       D  G      A       G  S   VR   
Sbjct: 117 AREKGAHVIEEITVTELLKDGDRVIGARTKDKTGKITDYHAPLTFDCTGKESFAAVRNGW 176

Query: 166 YPDHQIRKYVAIQQWFAEKHPVPFYSC---IFDNSITNCYSWSIS-KDGYFIFGGAY--- 218
                +   VA+  ++                       + W I   +     G      
Sbjct: 177 RIKDPMLNKVAVWTYYKGALRDEGIDAGATTVAFVPEKGWFWYIPQHNDIISVGVVAEGK 236

Query: 219 --PMKDGQTRFTTLKEKMSAFQF---QFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGE 273
                  +        +++  ++         +     V     +    C  +   L+G+
Sbjct: 237 YLSRDGVRDPEKMFLREVTQNKWIEQHLAVGKQFGPYYVTNEFSFHSKYCATEGLVLVGD 296

Query: 274 AAGFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRA--TRKLRLKLFGKIVKSRC 331
           A  F+      G+ +A+ S  +      +  +  + +  R     K   +    + K   
Sbjct: 297 AFCFLDPVFSSGLMFAMKSGVLAADYADEALKAADFSPARFEGYGKTLREGIENMRKLVY 356

Query: 332 LTA 334
              
Sbjct: 357 AFY 359


>UniRef50_D2R1S0 Tryptophan halogenase n=7 Tax=Planctomycetaceae RepID=D2R1S0_9PLAN
          Length = 428

 Score =  182 bits (463), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 62/379 (16%), Positives = 123/379 (32%), Gaps = 37/379 (9%)

Query: 5   DVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           DV +IG GP+GS ++  +A +   + L ++            G  L P+      R  + 
Sbjct: 17  DVIVIGGGPSGSTVSTLIAQQGYKVTLFEREHFPRFHI----GESLIPETYWVLKRLNML 72

Query: 65  LPVDVIANPQIFSVKTVDVAASLTRNYQRS---------YININRHAFDLWMKS-LIPAS 114
             +      +  SV+ V     L+  +  S            + R  FD  M        
Sbjct: 73  PKMRKTQFVKKHSVQFVTEKGKLSEPFYFSDNKPHECSQTWQVMRSEFDHMMIKNAAEHG 132

Query: 115 VEVYHDSLCRKIWREDDKWHVIFRAD--GWEQHITARYLVGADGANSMVRRHLYPD---- 168
           V+V+      ++  E  +   +  AD  G  + + A  +V A G +SM+   L       
Sbjct: 133 VQVHEGVRVLEVLFEGTRAVGVKVADERGNVRDVFASVVVDASGQSSMIMSRLGLREWDQ 192

Query: 169 --HQIRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSIS-KDGYFIFGGAYPM----- 220
              +   +   +  + +K      + +        + W I   +     G          
Sbjct: 193 ELKKAALWTYWEDAYRDKGRDEGATIVLQTQGKKGWFWYIPLHNNILSVGVVADYSYLFK 252

Query: 221 ----KDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAG 276
               KD +  +     K    Q +     +           ++      D   L+G+A G
Sbjct: 253 DRETKDHEAVYFEEVAKCPGLQPRLEGAKRIAPYRAAKEYSYRSREVAGDGWVLVGDAFG 312

Query: 277 FISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWR--ATRKLRLKLFGKIVKSRCLTA 334
           F+      G+  AL S ++    ++    + +T+  +  A     ++   ++ +  C   
Sbjct: 313 FLDPLYSSGVLLALRSGELAADAVVAGLREGDTSGAKLGAWGPNYIQGMERMRRLVCEFY 372

Query: 335 PALRKWIMRSGVAHIPQLK 353
                +     V   PQLK
Sbjct: 373 ---NGFSFGKFVKLYPQLK 388


>UniRef50_Q26DN3 Putative uncharacterized protein n=1 Tax=Flavobacteria bacterium
           BBFL7 RepID=Q26DN3_9BACT
          Length = 371

 Score =  182 bits (463), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 54/371 (14%), Positives = 125/371 (33%), Gaps = 34/371 (9%)

Query: 1   MEH-FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M   +DV I G G AG   A +L+    V+ +D           K CG  L+ +      
Sbjct: 1   MNKNYDVIIAGGGLAGLTAAIELSQNFNVLVID----PDAYPRHKMCGEYLSLEVDDYLQ 56

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYH 119
             G+ + +++  +       +       T +     I I+R++ D  +        +   
Sbjct: 57  SLGVNV-LELSDSKIDKFSFSQGSRTIRTASLPLGGIGISRYSLDYQLYVKAKEYSDFLC 115

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDH--QIRKYVAI 177
           D     +   D+ + V       E  + A+ ++ A G  S++ + L      +   ++A+
Sbjct: 116 D-RVVDVVSFDNYYKVQTT----EFELQAKQVLIATGKRSLLDKKLERPFIQKKSPWLAV 170

Query: 178 QQWFAEKHPVPFYSCIFDNSITNCYSWSI-SKDGYFIFGGAYPMKDGQ--TRFTTLKEKM 234
           +  +  + P      +  ++    Y+     ++G          K  +      T   K+
Sbjct: 171 KMHYRYEMPND---LVELHAFHGGYAGLSKVENGDVNLCYLVNYKTFKRYKNINTFNHKV 227

Query: 235 SAFQFQFGKTVKSEKCTVLFP-----SRWQDFVCGKDNAFLIGEAAGFISASSLEGISYA 289
                   K + +       P       ++          +IG+ AG I      G++ A
Sbjct: 228 LKVNKVLCKFLNTAVPVWDKPITISQISFEQKEPIHGKLIMIGDTAGLIHPLCGNGMAMA 287

Query: 290 LDSTDILRSVLLKQPE------KLNTAYWRATRKLR--LKLFGKIVKSRCLTA--PALRK 339
           + S       + +         +L + Y +  ++       +G+ ++   L     ++  
Sbjct: 288 IHSAQKASHYVTQFLNQDINQAQLLSNYSKDWKRTFSSRLRYGRWLQKILLNKSSSSIAY 347

Query: 340 WIMRSGVAHIP 350
           W+++     +P
Sbjct: 348 WLLKKFPFILP 358


>UniRef50_A3CW88 Geranylgeranyl reductase n=1 Tax=Methanoculleus marisnigri JR1
           RepID=A3CW88_METMJ
          Length = 365

 Score =  182 bits (463), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 62/345 (17%), Positives = 105/345 (30%), Gaps = 26/345 (7%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGL-----LAPDAQ 55
              DV ++G GPAGS  AR  A   + V+ +DK+   G       CG       +     
Sbjct: 3   NRCDVVVVGAGPAGSTAARYAAKTGLDVLLIDKRRTIG---VPVCCGEFNASSEVLASVL 59

Query: 56  RSFIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLI-PAS 114
            +        PVD     +                ++     ++R AFD  +        
Sbjct: 60  PNASGLDELFPVDPGLIRREIRGAVAVSPGGREYEFELPGYTVDRDAFDRHLADAAVREG 119

Query: 115 VEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKY 174
            E+  D+         +   V          + AR +V ADG  S V R    +      
Sbjct: 120 AELLPDTKFLG----REGSRVTTTRG----EVEARVVVAADGPLSRVCRSAGMERSAVLA 171

Query: 175 VAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKM 234
            AI      +          +      Y+W   K G    G     +D           +
Sbjct: 172 PAITCRVDGEFGDRLKFFFGNRIAPGGYAWVFPKRGCANAGLGVQKRDVPVPV-----LL 226

Query: 235 SAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTD 294
            AF    G + +  +     P         ++N   +G+AAG + AS+  GI+ A+    
Sbjct: 227 RAFLASQGFSARDVQA-GFVPVSGPIRETVRENVLAVGDAAGHVVASNGGGIAPAMICGR 285

Query: 295 ILRSVLLKQP--EKLNTAYWRATRKLRLKLFGKIVKSRCLTAPAL 337
           +            +   AY    R    +      +++ +    L
Sbjct: 286 LAGLAAANHLLRGEPLAAYEWEWRSAIGRELLAAARTKRMADRIL 330


>UniRef50_C5CNW2 Tryptophan halogenase n=13 Tax=Proteobacteria RepID=C5CNW2_VARPS
          Length = 455

 Score =  182 bits (462), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 60/362 (16%), Positives = 114/362 (31%), Gaps = 34/362 (9%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
           E  DV +IG GPAGS ++  LA + + + L +K            G  L P     F R 
Sbjct: 19  ESCDVLVIGGGPAGSTISALLAQQGRKVVLLEKEHHPRFHI----GESLLPANVELFDRL 74

Query: 62  GLTLPVDVIA---------NPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLI 111
           G+   V+ I          +P+      VD A    ++   S   + R   D  + ++  
Sbjct: 75  GVRDQVEKIGMPKFGIEFVSPEHEHRSYVDFAEGWDKSL-DSAWQVRRSELDELLFRNAA 133

Query: 112 PASVEVYHDSLCRKIWREDDKWHVIFR-ADGWEQHITARYLVGADGANSMVRRHL--YPD 168
               +       R +  + +   V  +  DG  +   AR++V A G ++++         
Sbjct: 134 ARGAQALEGCKVRDVAFDANGATVQAQMDDGARRSWRARFVVDATGRDTLLANKFRCKEK 193

Query: 169 HQIRKYVAIQQWFAEKHPVPF--YSCIFDNSITNCYSWSISK-DGYFIFGGAYPMKDGQT 225
           +      A+   F     +       I      + + W I   DG    G        +T
Sbjct: 194 NPDHNSTALFGHFTNAERLEGKKEGNISICWFAHGWFWFIPLADGTTSVGAVCWPYYLKT 253

Query: 226 RFTTLKEKM-------SAFQFQFGKTVKSEKCTVLFPS-RWQDFVCGKDNAFLIGEAAGF 277
           R   LK+              +       +       +  +       D   ++G+A  F
Sbjct: 254 RDKPLKDFFYDTIALCPVLVDRLKHATLVDDAVHATGNFSYSSTHATGDRYLMLGDAFTF 313

Query: 278 ISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPAL 337
           I      G+  A+ S      ++    ++           +R      + K     +  +
Sbjct: 314 IDPMFSSGVYLAMHSAFDGAGLVATALDRPA-----ELAPVRENFEAMMRKGPREYSWFI 368

Query: 338 RK 339
            +
Sbjct: 369 YR 370


>UniRef50_Q0HQD9 Monooxygenase, FAD-binding protein n=94 Tax=cellular organisms
           RepID=Q0HQD9_SHESR
          Length = 435

 Score =  182 bits (462), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 54/342 (15%), Positives = 103/342 (30%), Gaps = 27/342 (7%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
             DVAIIG GP+GS  A  L  + + + + +K            G  L P   +     G
Sbjct: 16  SVDVAIIGAGPSGSIAASLLHKQGKRVLVLEKQHFPRFSI----GESLLPCCMQFIEEAG 71

Query: 63  LTLPVDVIANPQI----FSVKTVDVAASLTRNY---QRSYININRHAFDLWMKSLIPA-S 114
           +   ++           F    V      T  +     +   + R  FD  +     +  
Sbjct: 72  MLEALNAAGFQYKNGAAFRRDGVYTTFDFTDKFTPGPGTTFQVQRANFDKLLADTAASFG 131

Query: 115 VEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQ--IR 172
           VE+ +      I    +    +    G    + A+Y++ A G   ++ R L  +    + 
Sbjct: 132 VEIRYGETVESIDLSANPRLSVRNEQGELYQVEAQYVLDASGFGRVLPRLLDLETPSSLP 191

Query: 173 KYVAIQQWFAEKHPVPFYSC------IFDNSITNCYSWSISKDGYFIFGGAY-------P 219
              AI     +    P +        +        Y      +G    G           
Sbjct: 192 TRSAIFTHVEDNISDPDFDRNKILISVHPQHQDIWYWLIPFSNGRCSLGVVAEPQLLARL 251

Query: 220 MKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFIS 279
             D + +  T+ ++    +        ++ C  L            D   L+G A  F+ 
Sbjct: 252 EGDLEQQLLTIVKEEPGLKALLANAKVAQPCATLKGYSANVSRLATDKFALLGNAGEFLD 311

Query: 280 ASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLK 321
                G++ A+ S  +    +LKQ       +        ++
Sbjct: 312 PVFSSGVTIAMQSASMAAKCVLKQLNGDTVDWPAEYSAPLMQ 353


>UniRef50_Q0SFD6 Pentachlorophenol monooxygenase n=6 Tax=Actinomycetales
           RepID=Q0SFD6_RHOSR
          Length = 480

 Score =  182 bits (462), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 63/373 (16%), Positives = 118/373 (31%), Gaps = 23/373 (6%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQ-VIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M+H DV +IG GP G  LA +LA   + V  LDK+    T          +         
Sbjct: 1   MKHIDVVVIGAGPTGCMLAGELAAAGRSVTVLDKRAAPSTLSR----AFGVHARTLELLD 56

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVA---ASLTRNYQRSYININRHAFDLWMKSLIPASVE 116
             GL   +                A     L   +    +   R+   L  +       +
Sbjct: 57  ARGLADRLVATGAASPGLKLWRGAALYLGRLRSRFPFVLVTPQRNVDALLEEHARDRGAD 116

Query: 117 VYHDSLCRKIWREDDKWHV-IFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYV 175
           +        + ++ +   V      G +    A Y VGADGA+S VR  +      +  +
Sbjct: 117 IIRGFTVTGVEQDGNGVRVHGHDNSGRDSTFLATYAVGADGAHSAVRTMIGQPFPGKAVL 176

Query: 176 AIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMS 235
                   +   P  + +  N++ + +++            A+  +        +  +  
Sbjct: 177 RSIMLADVELENPPDNLVTVNAVRDGFAFIAPYGDNLFRVIAWNRRHQVDDTAPVDREEL 236

Query: 236 AFQFQFGKTVKSEKCTVLFPSRW-----QDFVCGKDNAFLIGEAAGFISASSLEGISYAL 290
               +           V + SR+     Q         FL G+AA   S +  +G++  +
Sbjct: 237 RSTIEVAMGTDYGLGDVRWQSRFHCDERQVLQYRTGRVFLAGDAAHVHSPAGGQGMNTGI 296

Query: 291 DSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPAL--RKWIMR----- 343
                L   L    +  + A        R  +   +++S   T   +  R WI+R     
Sbjct: 297 QDAVNLGWKLAAVLDGADDAVLDTYHSERHPVGRLVLRSSGATMRMMIVRPWILRKIRNG 356

Query: 344 --SGVAHIPQLKD 354
             + +   P + D
Sbjct: 357 LVAALLGFPAIGD 369


>UniRef50_A7KH01 NapH2 n=10 Tax=Actinomycetales RepID=A7KH01_9ACTO
          Length = 446

 Score =  181 bits (459), Expect = 4e-44,   Method: Composition-based stats.
 Identities = 60/350 (17%), Positives = 113/350 (32%), Gaps = 33/350 (9%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
             FDV +IG GPAG+  A  L+ + + + +  + +          G  L P         
Sbjct: 31  GDFDVIVIGGGPAGATTAALLSKRGRRVLVLDRERFPRYHV----GESLIPGVMVPMEEL 86

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRS-------YININRHAFDLWMKSLIPA- 113
           GL   ++     + +    V     +  N+  S         +  R   D  +       
Sbjct: 87  GLKERMEAKGFERKYGGTLVWGNNEVPWNFSFSTGGRIPYAFHTRRADLDALVLDRAREL 146

Query: 114 SVEVYHDSLCRKIWREDDKWHVI---FRADGWEQHITARYLVGADGANSMVRRHLYPDHQ 170
              V  D+  +    ED +   +    R  G  Q   A  ++ A G   ++ R     + 
Sbjct: 147 GAFVVEDATVKDTIEEDGRVVGVRYALRGLGGTQEARASLVIDASGQARVIGRKYTEVNW 206

Query: 171 IRKY--VAIQQWFAEKHPVPFYSC--IFDNSITNCYSWSISKD-GYFIFGGAYPMKDGQT 225
             +   VA+  +F   H +P      I     ++ + W I  D G F  G     +    
Sbjct: 207 NEQLRNVAVWTYFDNCHRLPGDEWSNILIEGTSDGWFWGIPIDKGVFSVGYVTRSELATE 266

Query: 226 RFTTLKEKMS-------AFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFI 278
              +L++            +       ++          + +         L+G+AA F+
Sbjct: 267 SGKSLEDLFQSEIASTTKLKELLKDATQAAGYRSARDWSYTNDRFYGKGWALVGDAAAFV 326

Query: 279 SASSLEGISYALDSTDILRSV---LLKQP---EKLNTAYWRATRKLRLKL 322
                 G++ A  +   L  V   +L+ P   EK    Y  A ++    +
Sbjct: 327 DPLFSTGVALATLAGSTLSKVVDQILQYPAIEEKALDRYSNAYQEFFHDI 376


>UniRef50_UPI00018742EF geranylgeranyl reductase n=1 Tax=Corynebacterium amycolatum SK46
           RepID=UPI00018742EF
          Length = 426

 Score =  181 bits (459), Expect = 4e-44,   Method: Composition-based stats.
 Identities = 64/361 (17%), Positives = 109/361 (30%), Gaps = 40/361 (11%)

Query: 7   AIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTL 65
            I+G GP GSA A   A     V  +D +         K CG  L P A     R GL  
Sbjct: 2   LIVGAGPTGSAAAIHAARAGFSVTVVDSQ----RFPRDKTCGDGLTPRAIAELRRLGLDD 57

Query: 66  PVDVIAN------PQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIP-ASVEVY 118
            +                  T       +  +      ++R   D ++ +    A  +V+
Sbjct: 58  ELLRRNRNRGLKLHGFGGSITAPWPDDASGTFPAVGSAMSRVELDTFLLNAAADAGAQVF 117

Query: 119 HDSLCRKI---------WREDDKWHVIFR-ADGWEQHITARYLVGADGANSMVRRHLYPD 168
                RK+          R      V     +G    I+AR+L+ ADG  S V + L   
Sbjct: 118 DGVAARKVVLGALSSGGTRGHGVREVELSDREGKPHTISARWLLVADGVRSTVGKQLGRA 177

Query: 169 HQIRKYVAIQQW----FAEKHPVPFYSCIF------DNSITNCYSWSISKD-GYFIFGGA 217
                   +       F        +          +      Y W      G    G  
Sbjct: 178 WHRDSVFGVAARSYVSFDSVDVADDWIHSHLELRDSEGQTHPGYGWIFPLGAGQANVGCG 237

Query: 218 YPMKDGQTRFTTLKEKMSAF----QFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGE 273
                 +   T +K+ +  +    + Q+  +      + L P           N  L+G+
Sbjct: 238 ALATSARPARTNVKKLLREYHGQVREQWQMSEPEHVTSALLPMGGAVSNVAGPNWALLGD 297

Query: 274 AAGFISASSLEGISYALDSTDILRSV---LLKQPEKLNTAYWRATRKLRLKLFGKIVKSR 330
           AA  ++  + EGI Y ++S  +   +   +    + L  ++    R+     F    K  
Sbjct: 298 AACLVNPLNGEGIDYGMESARLAVELISSIGAGRDGLTHSWPALLREHYGTGFSLARKLA 357

Query: 331 C 331
            
Sbjct: 358 L 358


>UniRef50_A3EQU0 Geranylgeranyl reductase family protein n=2 Tax=Leptospirillum sp.
           Group II RepID=A3EQU0_9BACT
          Length = 416

 Score =  180 bits (458), Expect = 6e-44,   Method: Composition-based stats.
 Identities = 71/362 (19%), Positives = 126/362 (34%), Gaps = 33/362 (9%)

Query: 3   HFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
             D  ++GLGPAG+   R L+   ++V+ LD+          K CGG ++  A     + 
Sbjct: 14  KVDAIVVGLGPAGATAIRLLSEAGLRVVGLDR----AVFPRPKICGGGVSSRAIAFLPKG 69

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIP-ASVEVYHD 120
              +P  V        +   D +  L           +R   D ++      A  E+   
Sbjct: 70  WDEIPHTVSTGV---HLVFGDHSPVLWDMGYPIAYQFDRSDLDWFLLDRARLAGGEIRQG 126

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRK------- 173
              R + + ++ + +            +R+L+GADG  S V R L    +          
Sbjct: 127 ETIRSLAKREEIFRLQC---DSGPTYESRFLIGADGVTSSVLRFLAKSKRDDSDGAIPLK 183

Query: 174 ------YVAIQQWFAEKHPVPFYSCIFD-NSITNCYSWSISK-DGYFIFGGAYPMKDGQT 225
                 Y A +   + +        + D +S++  Y WS SK  G    G    +K  + 
Sbjct: 184 NSSYHMYPAAEVEISTQTSQRLSDVLIDLSSVSGGYGWSFSKSGGKKNVGVVGFVKPLKR 243

Query: 226 RFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGK--DNAFLIGEAAGFISASSL 283
              TL+  +  F  +          +      +  F         FLIG+A   +     
Sbjct: 244 PLETLRLFLETFPEREIFQDARGSSSAWLIPDYSRFDAHGKIPGLFLIGDAGAMVDPFLG 303

Query: 284 EGISYALDSTDIL-RSVLLK--QPEKLNTAYWRATRKLRLKL-FGKIVKSRCLTAPALRK 339
           EGI YAL S       ++L    PEK + +Y +    +  +  +   + S     P +  
Sbjct: 304 EGIYYALLSGARAVSDLILHRTSPEKASRSYAQWAHSIFREFSYAHKLASVVYRFPGIYF 363

Query: 340 WI 341
            +
Sbjct: 364 RL 365


>UniRef50_Q8KY40 RubN n=2 Tax=Streptomyces RepID=Q8KY40_STRCU
          Length = 518

 Score =  180 bits (458), Expect = 6e-44,   Method: Composition-based stats.
 Identities = 58/348 (16%), Positives = 105/348 (30%), Gaps = 19/348 (5%)

Query: 3   HFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            FDV I+G GP G  LA +L   +++ + L++         SK  G  L   +  S  R 
Sbjct: 23  DFDVLIVGGGPVGMLLAAELRISRVRAVVLER--LPERTPHSKAFG--LHARSLESLDRR 78

Query: 62  GLTLPVDVIANPQIFSVK-TVDVAASLTRNYQRSYINI--NRHAFDLWMKSLIPA-SVEV 117
           GL       A          +D     +         +   +   +  ++        E+
Sbjct: 79  GLLKRFREGARSWNNGHFAGLDEWVDFSTLDSAHGYALLSEQTRTERLLEERAAEFGAEI 138

Query: 118 YHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAI 177
                   I ++ D              + ARY VG DG  S+VRR    D         
Sbjct: 139 RRGHEVTAIRQDADGVEAEVAGPDGTYTLRARYAVGCDGGRSLVRREAGIDFPGTGGRVT 198

Query: 178 QQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTL--KEKMS 235
            +           + +          + +  D  +     +  +  +     L  +E  +
Sbjct: 199 ARLGDVILADRENAPMGMERTERGLLFCVPLDDTYHRVSTFDFEADREPGAELTLEELTA 258

Query: 236 AFQFQFGKTVKSEKCT---VLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDS 292
           + +  +G  + +       V   S  Q     +    + G+AA        +G++  L  
Sbjct: 259 SLREIWGDDLGAHSPRWLSVFTDSACQADRYREGRLLIAGDAAHTHFPVGGQGVNLGLQD 318

Query: 293 T-----DILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAP 335
                  +   V    PE L  +Y R  +    K+         L  P
Sbjct: 319 AFNLGWKLAAEVHGWAPEDLLDSYDRERQAPARKVLANTRAQIALMNP 366


>UniRef50_B5YDH3 FAD dependent oxidoreductase, putative n=2 Tax=Dictyoglomus
           RepID=B5YDH3_DICT6
          Length = 396

 Score =  179 bits (456), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 58/343 (16%), Positives = 112/343 (32%), Gaps = 16/343 (4%)

Query: 4   FDVAIIGLGPAGSALARKLAGK-MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +D+ I+G GP GS          ++ + +++  + G       C G L+  A   F    
Sbjct: 3   WDLVIVGGGPVGSFAGYLAGKNNIKTLIIEEHSKIGE---PLHCLGKLSIHAFEEF---- 55

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRS-YININRHAFDLWMKSLI-PASVEVYHD 120
             LP + I N              +     +     ++R  FD  M  L       +   
Sbjct: 56  -PLPKESIRNSLKGGYFFFPNGNFIKLKKSKPDSYILDRSLFDKNMAELAGKNGCTLLLS 114

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQW 180
           +    I  E++   +I       + I A+ ++ A+GA     + L             + 
Sbjct: 115 AKAIGIEIENEATRLIIEEKNRRRKIEAKVIINAEGAKRQFAKRLGLKPNPYLVSLQYEV 174

Query: 181 FAEKHPVPFYSCIFDNSI--TNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQ 238
              +        ++  S      + W          G A    +    F  L + ++  +
Sbjct: 175 IGLELLDKECVEVYLGSTYSKGFFLWVSPYGNLTKIGVAVQPNENPKIF--LDKFLNNLK 232

Query: 239 F-QFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILR 297
             +       +    + P           N  ++G+AAG+  +++  GI + L    I  
Sbjct: 233 KTRNSGIEIIKSYGGIIPILGPYEEYYYPNILIVGDAAGYNKSTTGGGIYFGLQGAQIAI 292

Query: 298 SVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKW 340
             + K  E  N  + +   KL  K FGK +K   +    L + 
Sbjct: 293 EQVKKYLEDNNINHLKTFPKLTYKKFGKELKFTKIVRKFLNQL 335


>UniRef50_Q31QX9 Geranylgeranyl reductase n=2 Tax=Synechococcus elongatus
           RepID=Q31QX9_SYNE7
          Length = 376

 Score =  179 bits (456), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 59/322 (18%), Positives = 110/322 (34%), Gaps = 15/322 (4%)

Query: 20  RKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVK 79
             LA + + + L ++ Q       K C G ++P   R F    L   VD   +   F+ K
Sbjct: 18  YHLARRDRQVLLLEQAQL---PRQKACAGGVSPQVARWFD-CDLRSVVDHGVDRLRFTWK 73

Query: 80  TVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVYHDSLCRKIWREDDKWHVIFR 138
             D         +  +  + R  FD ++ +        +   +    +  E D W V   
Sbjct: 74  LGD-PVEAELPSEEPFWMVRRDRFDHFLVEQAANLGARIEDGAAVTAVSAEGDGWLVTV- 131

Query: 139 ADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYV-AIQQWFAEKHPVPFYSCIFDNS 197
               ++   +R L+ ADGA   + + L    Q R+Y  A +            +      
Sbjct: 132 ---GDRAYRSRTLIAADGARGPLAQWLGFPSQKRRYAQACELDVPLPARPDSTAHFEFGL 188

Query: 198 ITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKC-TVLFPS 256
           + N Y W   K   +  G      +  T F  L   +  +   FG +   ++        
Sbjct: 189 VRNGYIWVFPKSDGYSIGIGTFRGNDATDFRGL---LETYLAGFGVSADLDRIVPHPLCV 245

Query: 257 RWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATR 316
                   + +A L+GEAA      + EGI  AL S       + +       A    +R
Sbjct: 246 WDGSQPLHRGSALLVGEAASLTDPFTAEGIRPALLSGMRAAEAIDRAIAGDRNALAGYSR 305

Query: 317 KLRLKLFGKIVKSRCLTAPALR 338
            ++ +    +  ++ +++   R
Sbjct: 306 TIQQEWGDSMAWAKRISSVFYR 327


>UniRef50_A3JWR6 Geranylgeranyl reductase n=1 Tax=Rhodobacterales bacterium HTCC2150
           RepID=A3JWR6_9RHOB
          Length = 394

 Score =  179 bits (455), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 56/341 (16%), Positives = 125/341 (36%), Gaps = 26/341 (7%)

Query: 25  KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG-LTLPVDVIANPQIFSVKTVDV 83
              V  +DK     +    K CGGL    ++++  R   + +  ++         +  D 
Sbjct: 32  GFSVALVDK----ASFPRDKLCGGLFTGRSRQNMTRIFNVDVYNELFLECSKMRFRAGDR 87

Query: 84  AASLTRNYQRSYININRHAFDLWMKS-LIPASVEVYHDSLCRKIWREDDKWHVIFRADGW 142
             S   +    ++ + R+ FD ++    +   V  +  S   ++ + ++   +       
Sbjct: 88  IISEVLDAPIMWLTMRRN-FDEFLFQTALGMGVNNFTGSAALEVNQNENCLQLK-----D 141

Query: 143 EQHITARYLVGADGANSMVRRHLY----PDHQIRKYVAIQQWFAEKHPVPFYSCIFDNSI 198
              ++ + L+G DG NS V + L+       +I   + ++     +        +  ++ 
Sbjct: 142 GSSLSYKVLIGCDGVNSFVAKSLFGSSFDPTKIGFGLEVEVPIEAEKSPEQTVEVDFSAA 201

Query: 199 TNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRW 258
              Y WS  K      G      +       +K++++ F  ++  +   +      P   
Sbjct: 202 DWGYGWSFPKHKSTTIGLGGINVENPK----MKQRLAEFLTRYPNSTDLKVKGQYLPFGD 257

Query: 259 QDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLK-----QPEKLNTAYWR 313
                GK N  L G+AAG +   + EGI+ A+ S ++             P+K    Y +
Sbjct: 258 FRKSPGKANILLAGDAAGLVDPVTGEGIALAMHSGELAALAASDAIKSNAPQKALRRYKK 317

Query: 314 ATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAHIPQLKD 354
           A R     L  +    R +  P   + + ++ +A+   L++
Sbjct: 318 ALRPTHQSL-RQAKLWRLMMFPKPMRSVFQNALANGSSLQN 357


>UniRef50_C4L154 Monooxygenase FAD-binding n=1 Tax=Exiguobacterium sp. AT1b
           RepID=C4L154_EXISA
          Length = 512

 Score =  179 bits (454), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 53/337 (15%), Positives = 93/337 (27%), Gaps = 19/337 (5%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKMQVI-ALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           E  DV I+G GP G  L   LA        +D+K               + P     F R
Sbjct: 3   EQVDVLIVGAGPTGLTLGLTLARYGVSFQIIDRKTTPSDNSR----AIGIQPRTIEVFSR 58

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNY-----QRSYININRH-AFDLWMKSLIPAS 114
             +   V   A              +    +        ++ + R    +  ++  +   
Sbjct: 59  LDVAQEVLERARTIERGNLYFSGQWTAKLEFSKLVTPYPFVTLLRQNETEEILERALRKH 118

Query: 115 VEVY-HDSLCRKIWREDDKWHVIFR-ADGWEQHITARYLVGADGANSMVRRHLYPDHQIR 172
             V         I +   +        DG  + + A+Y+V ADGANS VRR L      +
Sbjct: 119 GHVVKRGETLSSITQYPSRTIAHLTATDGMTRAVEAKYVVAADGANSSVRRMLALPFSGK 178

Query: 173 KYVAIQQWFAEKHPVPF-YSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLK 231
            +         K   P     +                   I        D   + + L+
Sbjct: 179 SFKEAWVLADLKADWPISREEVHIFFSDRGVLEVFPLTDETIRITGNLRTDESFQESDLQ 238

Query: 232 EKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALD 291
           E +             E  ++             +   L+G+AA   S    +G++  + 
Sbjct: 239 ELVEQRSHMPVHIHDVEWFSLFRVHNRMVDTFIHNRIILMGDAAHINSPVGGQGMNTGIA 298

Query: 292 STDILRSVL-----LKQPEKLNTAYWRATRKLRLKLF 323
               L   L        P  + + Y      +   + 
Sbjct: 299 DAFNLGWKLWLHLKTGAPHHVVSTYRDEREHVARNVL 335


>UniRef50_Q46C42 Geranylgeranyl reductase n=5 Tax=Methanosarcina RepID=Q46C42_METBF
          Length = 391

 Score =  179 bits (454), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 54/327 (16%), Positives = 107/327 (32%), Gaps = 27/327 (8%)

Query: 24  GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTVDV 83
             +  + ++K+         KPCGG L+             LP  +I             
Sbjct: 23  RGLLTLLIEKE----NFPRYKPCGGALSSYGLSCLD---FKLPESIIERNIPKVGVYFRD 75

Query: 84  AASLTRNYQRSYININRHAFDLWMKSLIP-ASVEVYHDSLCRKIWREDDKWHVIFRADGW 142
                       + ++R  FD ++      A +EV+       +  ++D   V       
Sbjct: 76  RFVEGMKENNLALLVSRKVFDNFLLEKARGAGIEVHTGEEVLDLVEKEDFVEVRTT---- 131

Query: 143 EQHITARYLVGADGANSMVRRHLYPDHQIRKY-VAIQQWFAEKHP-----VPFYSCIFDN 196
           +      +++ ++G+   ++  + P  +I +Y + +     +         P    I   
Sbjct: 132 DNTYLGSFVLISEGSGGTLKYKVRPRDKITEYGLGLVSEIPDDDEVIRNRFPGTINIHFG 191

Query: 197 SITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPS 256
                Y W     GY+  G     +  +    TL + +          V+S     + P 
Sbjct: 192 VAKGGYGWIFPHAGYYSAGIVGAAQYLEHPKKTLLDFLEENGLSGDFPVRS----HVIPK 247

Query: 257 RWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLK---QPEKLNTAYWR 313
                        L G+AAGF+ A + EG+SYA+ S  +    +        KLN+   +
Sbjct: 248 GGIKRKILNSRLLLSGDAAGFVDAFTGEGLSYAIRSGQLAAETVADLVMYSLKLNS--LK 305

Query: 314 ATRKLRLKLFGKIVKSRCLTAPALRKW 340
           A      + FG  + S       + ++
Sbjct: 306 AYEFSCRQEFGNYLSSSLKLDKIMHRF 332


>UniRef50_C6VXB5 FAD dependent oxidoreductase n=1 Tax=Dyadobacter fermentans DSM
           18053 RepID=C6VXB5_DYAFD
          Length = 379

 Score =  179 bits (454), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 63/354 (17%), Positives = 120/354 (33%), Gaps = 39/354 (11%)

Query: 2   EHFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           EHF+ AI+G G AG  LA +LA   + V+  +K        F K CG  ++ ++      
Sbjct: 6   EHFECAIVGGGLAGLCLAIQLADRGISVVLFEK----NRFPFHKVCGEYISMESWPFLES 61

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKS-LIPASVEVYH 119
            GL L  ++          + +    L          I+R   D  +    +   V V  
Sbjct: 62  LGLPLA-EMELPKISRLGISSERGFVLNHRLGMGGFGISRFTLDHALFELAVRKGVSVMQ 120

Query: 120 DSLCRKIWRE-DDKWHVIFRADGWEQHITARYLVGADGANS----MVRRHLYPDHQIRKY 174
           +     +    DD + V   A        A+ + G+ G        +  +       + Y
Sbjct: 121 ECRVIDVQGNADDGFQVRTSAGD----FQAQVVCGSYGKYGPQFIRLHENDALKIDSQNY 176

Query: 175 VAIQQWFAEKHPVPFYSCIFDNSITNCY-SWSISKDGYFIFGGAYPMKDGQTRFTTLKEK 233
           + ++       P      I  ++ T  Y   S     ++        ++       +K+ 
Sbjct: 177 IGVKYHIKTDFPTDR---IELHNFTGGYCGISKVDQDWYCLCYLTTARNLIANGKDVKQM 233

Query: 234 MSAFQFQ--------FGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEG 285
             A  F+              + +  V+   ++       +  FL+G+AAG I+     G
Sbjct: 234 EEAVLFKSPFLKHYFTHSEFVNAQPLVISNVQFSKKQTHSNGIFLLGDAAGSITPLCGNG 293

Query: 286 ISYALDSTDILRSVL----------LKQPEKLNTAYWRATRKLRLKLFGKIVKS 329
           +S  + ++ +L   L           K  E  ++A W A    R++    + K 
Sbjct: 294 MSMGMRASKLLAEQLYLFFDGKQTHDKASEHYHSA-WNAAFGTRVRAGYHLQKL 346


>UniRef50_Q2RLB4 Geranylgeranyl reductase n=1 Tax=Moorella thermoacetica ATCC 39073
           RepID=Q2RLB4_MOOTA
          Length = 341

 Score =  179 bits (454), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 64/335 (19%), Positives = 105/335 (31%), Gaps = 19/335 (5%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           M  +D  + G GPAGS  AR +A     + L +K      G+   C   +          
Sbjct: 1   MLKYDAVVAGAGPAGSTAARVVAAAGARVLLIEKR--ARVGYPVQCAEYVPALIASEVDF 58

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKS-LIPASVEVYH 119
              ++ + V                    +       +NR  FD  +    + A  E++ 
Sbjct: 59  GEKSIALAV-------GTLVTFFPDGTVTSTPAPGYILNREVFDASLAEGAVKAGAELWL 111

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQ 179
            +    +    D   +I +A+G  Q + A  ++GADG  S+V R      +     A+Q 
Sbjct: 112 KATVEDLT---DTSLIIRQANGRRQEVEAGVIIGADGPLSLVARTRGWP-RATLAAAVQV 167

Query: 180 WFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQF 239
             A   P+      FD      Y+W   K      G      +  T    L   +    +
Sbjct: 168 EMALPEPMQVTRVYFDPLYRGGYAWVFPKGKTANVGVGLVPGEI-TPAAALTHFLRRLGW 226

Query: 240 QFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSV 299
           Q    V+  +   L P         +    L G+A GF    +  GI  A+ S  +    
Sbjct: 227 QQQNIVR--RTGGLIPVAGPYQEVHRGRVLLCGDAGGFTHPVTGAGILTAILSGRLAGEA 284

Query: 300 LLKQP--EKLNTAYWRATRKLRLKLFGKIVKSRCL 332
                        Y  + R L      +    R  
Sbjct: 285 AAAYLGSGAPLATYEESWRDLLGPALARGQAGRRR 319


>UniRef50_B0TPS5 Tryptophan halogenase n=12 Tax=Proteobacteria RepID=B0TPS5_SHEHH
          Length = 435

 Score =  178 bits (452), Expect = 3e-43,   Method: Composition-based stats.
 Identities = 52/353 (14%), Positives = 107/353 (30%), Gaps = 40/353 (11%)

Query: 5   DVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           D+AIIG GP+GS  A  L  + + + + +K            G  L P   +      + 
Sbjct: 21  DIAIIGAGPSGSIAASLLHAQGKKVLVLEKQHFPRFSI----GESLLPCCMQVIDEANML 76

Query: 65  LPVDVIA----NPQIFSVKTVDVAASLTRNY---QRSYININRHAFDLWMK-SLIPASVE 116
             V+       N   F  +    +   T  +     +   + R  FD  +    +   VE
Sbjct: 77  EAVNQAGFQFKNGAAFRHQDKYTSFDFTDKFTQGPGTTFQVERANFDKLLADEAVSQGVE 136

Query: 117 VYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQ--IRKY 174
           + +      I    +    +    G  Q I A++++ A G   ++ R L  +    +   
Sbjct: 137 IRYGHTVESIDLSAEPSLSVSNGKGQTQTINAKFVLDASGFGRVLPRLLDLEKPSTLPTR 196

Query: 175 VAIQQWFAEKHPVPFYSC------IFDNSITNCYSWSISKDGYFIFGGAYPMK------- 221
            A+     +    P +        +  ++    Y      DG    G     +       
Sbjct: 197 SAVFNHIHDNISDPNFDRNKILISVHPDNQDIWYWLIPFSDGRCSVGVVGEPEQLSSLSG 256

Query: 222 -------------DGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNA 268
                        D      T+  +    +          +  +L            D  
Sbjct: 257 YASNGFSDEIGNSDLDKILKTMINQEPGLRALLADAELINESGLLKGYSANVKTLATDKF 316

Query: 269 FLIGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLK 321
            L+G A  F+      G++ A+ S  +    +++Q +     + +   +  +K
Sbjct: 317 ALLGNAGEFLDPVFSSGVTIAMQSASMAAKTVIRQLDGERVDWQQDYAEPLMK 369


>UniRef50_D1RDY9 FAD dependent oxidoreductase domain protein n=1 Tax=Legionella
           longbeachae D-4968 RepID=D1RDY9_LEGLO
          Length = 400

 Score =  178 bits (452), Expect = 3e-43,   Method: Composition-based stats.
 Identities = 64/382 (16%), Positives = 115/382 (30%), Gaps = 41/382 (10%)

Query: 5   DVAIIGLGPAGSALARKLAGKMQVI-ALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           DV IIG GPAG+  A  LA     +  ++KK         K CG  ++  +       GL
Sbjct: 4   DVLIIGGGPAGATTAILLAKAGWSVGLIEKKE----FPRKKVCGEFISATSLPLLQILGL 59

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQ-------RSYININRHAFDLWMKSLIP-ASV 115
                    P++  V        LT N              + R   D  + +      V
Sbjct: 60  EKFYFENGGPEVTRVGLYAGDVILTANMPHMNSSANPYGRALGREYLDTALINEAKLNGV 119

Query: 116 EVYHDSLCRKIWREDDKWHVIFRADGWEQHITARY-LVGADGANSM-VRRHLYPDHQIRK 173
            ++       +  ++  +    + +           +V A G+    +       H+   
Sbjct: 120 TIWQPCEAIHLQNKNGLFFCTIKKEAKISETVCSLRVVMAYGSWGKKIDSSDAKIHKDCD 179

Query: 174 YVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKD----------- 222
            +A +  F           +   +    Y   +      +       +D           
Sbjct: 180 LLAFKAHFKNCSLSKNMMPLL--AFPGGYGGLVHSSPQQVALSCCIRRDTLKNLRLKSPD 237

Query: 223 ---GQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFIS 279
              G+  F  +KE     +  F      +K     P +     C K+  F +G  AG   
Sbjct: 238 LPAGEAVFKYIKEHCRGVREVFELAHIDDKWLAAGPIQPGIRTCYKNGIFFVGNIAGEAH 297

Query: 280 ASSLEGISYALDSTDILRSVLLK-------QPEKLNTAYWRATRKLR-LKLFGKI-VKSR 330
               EGIS A+ S  +L   L++               Y +  RK    +++  I +   
Sbjct: 298 PVVAEGISMAMQSAWLLSQSLIQFNMKQNNNLNDAGKYYTQQWRKYFAHRIYASIFLAHL 357

Query: 331 CLTAPALRKWIMRSGVAHIPQL 352
            +  P  R  ++   +   P L
Sbjct: 358 AMLKPWGRALLL-PIIQQFPAL 378


>UniRef50_A8M2V9 Geranylgeranyl reductase n=5 Tax=Actinomycetales RepID=A8M2V9_SALAI
          Length = 406

 Score =  178 bits (451), Expect = 3e-43,   Method: Composition-based stats.
 Identities = 73/310 (23%), Positives = 113/310 (36%), Gaps = 14/310 (4%)

Query: 40  EGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININ 99
               K CG  +A  A       G+  PV   A P            ++ R   R    + 
Sbjct: 64  FPRDKACGDGIAAHALDVLDELGVPDPVAGYA-PVSTLRLVAPSGGAVARALPRQAYTVP 122

Query: 100 RHAFDLWMKSLIPASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANS 159
           R  FD  + +   A+         R++    D+  +       +  ITAR +VGADGA S
Sbjct: 123 RTVFDARLVAAAVAAGARLRRHAVRQVEVRADRVVL-------DGRITARAVVGADGAGS 175

Query: 160 MVRRHLY--PDHQIRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSIS-KDGYFIFGG 216
           +VRR L   P+      +AI+ +       P    +   +    Y+WS    DG    G 
Sbjct: 176 VVRRALGHRPNPDRHLALAIRGYAPAPSGRPEQLIVTSATRWPAYAWSFPIGDGRANVGY 235

Query: 217 AYPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAG 276
              ++        L E++ A          +       P      V G+  A L G+A  
Sbjct: 236 GEVLRGESLTRGHLLERLGALLPGVDPAAVTALRAHHLPLSTHRPVPGRGRAVLAGDALS 295

Query: 277 FISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPA 336
            I+  + EGI YAL S  +  +   + PE     Y  A   LR +L G +  S      A
Sbjct: 296 LINPFTGEGIFYALLSGTLAGAAASRAPEHAARRYAEA---LRRRLGGHLRHSSAAAWLA 352

Query: 337 LRKWIMRSGV 346
            R+ ++ + V
Sbjct: 353 RRRSVVDAAV 362


>UniRef50_Q3JCF5 Geranylgeranyl reductase n=2 Tax=Nitrosococcus oceani
           RepID=Q3JCF5_NITOC
          Length = 384

 Score =  177 bits (450), Expect = 4e-43,   Method: Composition-based stats.
 Identities = 58/334 (17%), Positives = 114/334 (34%), Gaps = 24/334 (7%)

Query: 26  MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD-GLTLPVDVIANPQIFSVKTVDVA 84
            +V  +++K    T    K CGGLL+  AQ+ F++  G      ++      +       
Sbjct: 27  FKVALVERK----TFPREKLCGGLLSARAQKEFMQIFGENKWPAMVERTAQGASFYYQTR 82

Query: 85  ASLTRNYQRSYININRHAFDLWMKSLIPASVE-VYHDSLCRKIWREDDKWHVIFRADGWE 143
                +  + +   +R  FD  + +L   +   +    +   +  +     +        
Sbjct: 83  YLNGVHDHQPFFFTSRIHFDACLAALAREAGAYLLEGIVVTSLEADGKAVRL-----NNG 137

Query: 144 QHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEKHPVPFYSC----IFDNSIT 199
           + + A ++VGADG  S +   +      +K +A+         +   +     I+     
Sbjct: 138 KMLKADFVVGADGVRSRIAEAILLHTASKKNLALGLEIEVPLELTTKTVVDPEIYLGVAK 197

Query: 200 NCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQ 259
             Y W   K      G    +       +T    +      +G            P    
Sbjct: 198 WGYGWIFPKKETQTVGIGGLLTKNPDLKSTFNTFLRQ---HYGSLPNIRCKGYHLPFGSY 254

Query: 260 DFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDI-----LRSVLLKQPEKLNTAYWRA 314
               G+ N  L+G+AAG +   + EGI++A+ S  +     + +    QPE     Y R 
Sbjct: 255 KRNPGRANILLVGDAAGLVEPVTGEGIAFAMQSGRLAAKAIVAAAGAGQPESALKYYLRE 314

Query: 315 TRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAH 348
            +   + LF +    R L  P   + +  S + H
Sbjct: 315 YQS-IVSLFSQAKMMRYLVFPDPMQRLFVSLLPH 347


>UniRef50_Q8KLM2 StaK n=1 Tax=Streptomyces toyocaensis RepID=Q8KLM2_STRTO
          Length = 435

 Score =  177 bits (450), Expect = 5e-43,   Method: Composition-based stats.
 Identities = 56/361 (15%), Positives = 98/361 (27%), Gaps = 40/361 (11%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQR-SFIR 60
           E FDV + G GPAGS  A  +A +   + L +K            G  L P         
Sbjct: 4   ETFDVVVAGGGPAGSTAASLVAMQGHRVLLVEKEVLPRHRV----GESLLPSTVHGVCRM 59

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSY-----------ININRHAFDLWMKS 109
            G+T  +     P            +    +                  +R  FD  +  
Sbjct: 60  LGVTDELAETDFPVKRGATFQWGGRAEPWAFSFGASSRLTDATSFAYQADRARFDEILLK 119

Query: 110 LI-PASVEVYHDSLCRKIWREDDKWHV--IFRADGWEQHITARYLVGADGANSMVRRHLY 166
                 V V        +  E D+         DG E  + AR+++ A G  S +   + 
Sbjct: 120 NAKRKGVVVREGCSVTAVVEEGDRVTGLRHTDPDGGEHEVGARFVIDASGHESPLSASVG 179

Query: 167 PDHQIR---KYVAIQQWFAE---KHPVPFYSCIFDNSITNCYSWSISK-DGYFIFGGAY- 218
                    + +A+  +F     + P P        +    + W +    G    G    
Sbjct: 180 GTRDRAGSFRGLALSGYFGNGCKRLPEPRSGDGLSVTFDGGWFWYVPLFGGLTSVGAVVS 239

Query: 219 ------PMKDGQTRFTTLKEKMSAFQFQFGKTVKS-----EKCTVLFPSRWQDFVCGKDN 267
                    D +  F  L  +  A      + ++       K  V     +      +  
Sbjct: 240 EERAEKLQDDREEAFKALIAECPAISDLLSEGMRVTAGKYGKLRVREDYVYHRTTFWRPG 299

Query: 268 AFLIGEAAGFISASSLEGISYALDSTDILRSVLLK--QPEKLNTAYWRATRKLRLKLFGK 325
             L+G+AA  +      G+  A  S  +    +      +               +  G 
Sbjct: 300 MLLVGDAACSVDPLFSSGVHLATYSALLAARSINSVLAGDVDEKTALTEFEARYRRELGA 359

Query: 326 I 326
            
Sbjct: 360 F 360


>UniRef50_Q2JG94 Putative uncharacterized protein n=1 Tax=Frankia sp. CcI3
           RepID=Q2JG94_FRASC
          Length = 409

 Score =  177 bits (449), Expect = 7e-43,   Method: Composition-based stats.
 Identities = 67/310 (21%), Positives = 106/310 (34%), Gaps = 27/310 (8%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGK---MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSF 58
             +DV I+G GPAGS  A  L  +   ++V+  DK          K CG  L   A  + 
Sbjct: 4   GSYDVVIVGAGPAGSVAAFALKRRNPRLRVLLTDK----AVFPRDKACGDGLGAGAVAAL 59

Query: 59  IRDGLTLPVDVIANPQIFSVKTVDVA-----ASLTRNYQRSYININRHAFDLWMKSLIPA 113
            R GL   V    +P    V   D                S   + R   D  + +    
Sbjct: 60  RRLGLLGVVHDAISPLSVRVSGPDGTEATAVGPTVAGRDLSGYVLPREILDARLVAAARE 119

Query: 114 -SVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIR 172
             VE+   +         +   + F+       + A  ++GADGA S VRR L    Q  
Sbjct: 120 VGVEMREGTSYHSSELTGNSRVITFKTGSRSNSVEAALMIGADGAYSRVRRDLGVGRQDD 179

Query: 173 KY--VAIQQWFAEKHPVPFYSCI------FDNSITNCYSWSIS-KDGYFIFGGAYPMKDG 223
           ++  +A++ +     P      +      F + +   Y W     D     G   P+   
Sbjct: 180 RFSSIAMRSYAKFSDPRRAPQEVMPLRLDFSDKVLPGYGWVFPVSDDVVNLGVGLPVSTM 239

Query: 224 QTRFTT----LKEKMSAFQFQFGKTVKSEKC-TVLFPSRWQDFVCGKDNAFLIGEAAGFI 278
           + +       L   +   + +     +  K  +   P   +        A LIG+AA  I
Sbjct: 240 REKSLNPHNLLSAYVEDLRARGFIVEEPNKLLSHYLPHAGKLAPMAHPRAALIGDAAASI 299

Query: 279 SASSLEGISY 288
           +  S EGI Y
Sbjct: 300 NPLSGEGIVY 309


>UniRef50_A8ME14 Geranylgeranyl reductase n=1 Tax=Caldivirga maquilingensis IC-167
           RepID=A8ME14_CALMQ
          Length = 362

 Score =  177 bits (449), Expect = 7e-43,   Method: Composition-based stats.
 Identities = 65/298 (21%), Positives = 104/298 (34%), Gaps = 22/298 (7%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           +D+ IIG GPAG+A A   +       +  K +       KPCGG L P         GL
Sbjct: 2   YDLIIIGSGPAGNAAALVASRLGVRALIIDKSK---HPRVKPCGGGLTPKTIALSRILGL 58

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQRSYINI-NRHAFDLWMKSLIPASVEVYHDSL 122
            L    +   +   V  V  A S    ++   I +  R   D +M +    +   Y +  
Sbjct: 59  DL--SEVIEHECGEVLVVTHAGSFVMRFKEPMIRVSRRERLDEFMFNEAVNNGVEYVNDE 116

Query: 123 CRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFA 182
             ++     K  VI    G      A++++GADGA S V R +         VA+    +
Sbjct: 117 VLRVRETPSKVEVI----GRSSVYEAKWVIGADGAPSRVGRSIGV-MPRSNAVALMNIAS 171

Query: 183 E--KHPVPFYSCIFDNSITNCYSWSISKD-GYFIFGGAYPMKDGQTRFTTLKEKMSAFQF 239
                       +    I   Y+W      G +  G    +K   +    L   ++    
Sbjct: 172 GNPIINTGDACILDFTRIKWGYAWLFPLSHGEYDVGLGSALKGRYSNL--LLSYVNELGL 229

Query: 240 QFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILR 297
           + G+ +       L P R  +         L G+A G     + EGI  A+ S  +  
Sbjct: 230 KPGRLI-----GHLIPYRPPN-SASTRRVMLTGDALGLADPVTGEGIFQAMMSGALAA 281


>UniRef50_D2C3Q7 Electron-transferring-flavoprotein dehydrogenase n=6
           Tax=Thermotogaceae RepID=D2C3Q7_THENR
          Length = 438

 Score =  176 bits (448), Expect = 8e-43,   Method: Composition-based stats.
 Identities = 57/382 (14%), Positives = 123/382 (32%), Gaps = 48/382 (12%)

Query: 1   ME-HFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSF 58
           M+  FDV ++G GP+G + A  LA   ++V  ++K    G++      GG+L     +  
Sbjct: 1   MKIEFDVVVVGAGPSGLSCAYVLAKNGLKVAVVEKGEYPGSKN---VMGGVLYVHPLKEI 57

Query: 59  IRDGLTLPVDVIANPQIFSVKTVD----------VAASLTRNYQRSYININRHAFDLWMK 108
           + D L    +  A  +    + +              ++      +   + R  FD W  
Sbjct: 58  MPDFLEKAANSKALERNVIEQNLWLLGNEGVIKIGHRNVEWKENPNAFTVLRANFDRWFA 117

Query: 109 SLIP-ASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYP 167
             +  A   +   +      R +            +  I ++ +V A+G N ++      
Sbjct: 118 QEVEKAGALIIPKTKVEDFLRNEKGEIAGVVTSRPKGEIHSKAVVIAEGVNPILTMKAGL 177

Query: 168 DHQI--RKYVAIQQWFAEKHPVPFYSCIFDNSITNC---------------YSWSISKDG 210
             +      VA+        P    + +F     +                  +  +   
Sbjct: 178 RKEDLKPHMVAVAVKEVISVPEDVVNRVFGVEGNDGATIELLGSWSEGMFGMGFLYANRS 237

Query: 211 YFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKTVKS--------EKCTVLFPSRWQ--D 260
               G    ++D + +     + +   +     +           E    L P       
Sbjct: 238 SVSLGCGVLLEDLRKKKIKPYQLLENLKNHPVISDMLGEYRNNTMEYLAHLIPEGGYYAM 297

Query: 261 FVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRL 320
                D   + G+AA  +++   EG ++A+ S  +    LL+  EK + +      K+  
Sbjct: 298 PKVYGDRVLVCGDAAMLVNSIHREGSNHAITSGRLAAETLLEAFEKGDFS-----EKILK 352

Query: 321 KLFGKIVKSRCLTAPALRKWIM 342
             + ++ +S  L      K +M
Sbjct: 353 NYYLRLKESFILKDLEKYKDLM 374


>UniRef50_Q4MV03 Geranylgeranyl hydrogenase BchP, putative n=12 Tax=Bacillus cereus
           group RepID=Q4MV03_BACCE
          Length = 409

 Score =  176 bits (448), Expect = 8e-43,   Method: Composition-based stats.
 Identities = 58/354 (16%), Positives = 112/354 (31%), Gaps = 42/354 (11%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           + +DV I G   AGS LA  LA     V+ +D+                   +       
Sbjct: 3   KTYDVIITGARCAGSTLAIYLAKAGFHVLLVDR----ANFPRDTLLTHTFFNNTVALLRE 58

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSY-----ININRHAFDLWMKSLIPA-- 113
            G+   +     P +  +K       +       Y       I R   D  +     +  
Sbjct: 59  TGVLDKLLETKVPPVRDIKFQFEDTVIEGLIPEVYGEESCYCIRRTYLDHILLEQAKSQM 118

Query: 114 SVEVYHDSLCRKIWREDDKWHVI--FRADGWEQHITARYLVGADGANSMVRRHLYPDHQI 171
           +V V        + R+D+    +     D  +Q   AR +VGADG +S++R+ +  + +I
Sbjct: 119 NVTVLEGFRVTDVIRDDETVIGVKGLDGDNEKQEFLARLVVGADGRSSIIRKLVKSELKI 178

Query: 172 RKYVAIQQWFAEKHPV--PFYSCIFDNSITNCYSWSIS-KDGYFIFGGAYPMKDGQ---- 224
                +  +F                  I +  +      D  ++  G +P+++ +    
Sbjct: 179 SIPATVGIYFGYFSGFRHDNVPKFEVYKIKDNTAILFPTNDDLYVIVGIFPLENKELIER 238

Query: 225 ---TRFTTLKEKMSAF------QFQFGKTVKSEKCTVLFPSRWQDFVCGKD---NAFLIG 272
                 + L+   +          +       E    +      D    K       L+G
Sbjct: 239 LKLNPESCLRNFFTDNFPNTTIGARLKNAELVEPVKGIL---GYDNYWYKGMGKGWALVG 295

Query: 273 EAAGFISASSLEGISYALDSTDILRSVLLKQPEKLNTA------YWRATRKLRL 320
           +A  F      +GI  A+    IL ++L K   + + +      Y +A     +
Sbjct: 296 DAVCFKDPGMAQGIHDAICGARILSNILSKYKGQSDQSNQMSEEYQKAIEDEFM 349


>UniRef50_C4XQT1 Geranylgeranyl reductase n=2 Tax=Desulfovibrio RepID=C4XQT1_DESMR
          Length = 391

 Score =  176 bits (447), Expect = 1e-42,   Method: Composition-based stats.
 Identities = 60/313 (19%), Positives = 86/313 (27%), Gaps = 34/313 (10%)

Query: 3   HFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
             DV I+G GPAGS  A  LA     V+ LDK          K C GLL   A     R 
Sbjct: 4   THDVVIVGAGPAGSTAAHVLASRGASVLVLDKAE----FPRDKLCAGLLTWKAVDVLERV 59

Query: 62  GLTLPVDVIA-----NPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLI-PASV 115
               P  ++A                            +    R  FD  +      A  
Sbjct: 60  FGDAPEGLLASGVFNAAPAGYCIRFRDHIIAQGEMFYPFHLTKRRVFDKHLADRAVKAGA 119

Query: 116 EVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHL---YPDHQIR 172
           +V       ++                 +    RY++G DG  S+VRR       + +  
Sbjct: 120 DVRLGLAVSRVDPATGTVT-----TADGREFRGRYVLGCDGVASVVRRACPFDGANWKAG 174

Query: 173 KYVAIQQWFAEKHPV----------PFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKD 222
              A++ +     P             +  ++   +   Y W          G       
Sbjct: 175 MGGALEFYIDRDDPRLAAPAHADLRAEHPTVYAGFLRAGYGWVFPHADRLAIGIG---GH 231

Query: 223 GQTRFTTLKEKMSAFQFQFGKTVKSEKCT--VLFPSRWQDFVCGKDNAFLIGEAAGFISA 280
                   + K   F    G   +          P              L G+AAG +  
Sbjct: 232 SARHGREFRAKFREFVSFLGLPPELADAAKGHGLPYGNYIEKPWHGRVMLAGDAAGLVET 291

Query: 281 SSLEGISYALDST 293
              EGI YAL S 
Sbjct: 292 LFGEGIYYALRSG 304


>UniRef50_C8VZJ8 Electron-transferring-flavoproteindehydrogenase n=1
           Tax=Desulfotomaculum acetoxidans DSM 771
           RepID=C8VZJ8_DESAS
          Length = 434

 Score =  176 bits (447), Expect = 1e-42,   Method: Composition-based stats.
 Identities = 53/332 (15%), Positives = 106/332 (31%), Gaps = 46/332 (13%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M+ FD  ++G GPAG+  A  LA    +V+ L++    G +  S   G  L     R   
Sbjct: 1   MKQFDAIVVGGGPAGTTAALVLARAGMRVVVLERGEYPGAKNVS---GAALY--GTRLLE 55

Query: 60  RD----GLTLPVDVIANPQI------FSVKTVDVAASLTRNYQRSYININRHAFDLWMKS 109
           R      L  P++     ++       ++ ++D  +        +   + R  FD W+  
Sbjct: 56  RLHPGFWLDAPIERYITRKVLGFMSEHALTSIDFKSENMGLPPYNAFTVIRPKFDRWLAL 115

Query: 110 LIPASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDH 169
               +  +           +++      R    +  + A  ++ ADG NS + R      
Sbjct: 116 KAEEAGALIISGTVVDGLIKENGVIKGVRTRRDKGELYADIVIAADGVNSFLAREAGLQR 175

Query: 170 QIR--------------KYVAIQQWFAEKHPVPFYSCIFDNSITN---CYSWSISKDGYF 212
           +++                  I++ F         +  F  S+T       +  + +   
Sbjct: 176 ELKANELSLGIKEIIALDRQTIEERFQ-LSGNEGVTHEFVGSVTGEATGGGFLYTNEDSL 234

Query: 213 IFGGAYPMKDGQTRFTTLKEKMSAF------QFQFGKTVKSEKCTVLFPSRW--QDFVCG 264
             G    +           E +         +      +  E    + P           
Sbjct: 235 SIGVIMQVSSMLENRIRPYELLEKLKSHPSVRPLVRGGLAKEYSAHMIPEGGWKMFPKLF 294

Query: 265 KDNAFLIGEAAGFISASSL---EGISYALDST 293
                + G+AAG + A +    +GI+YA+ S 
Sbjct: 295 APGLLVAGDAAGMVLA-TGYYLQGINYAMISG 325


>UniRef50_D1BBC7 Geranylgeranyl reductase family protein n=11 Tax=Actinomycetales
           RepID=D1BBC7_SANKS
          Length = 431

 Score =  176 bits (446), Expect = 1e-42,   Method: Composition-based stats.
 Identities = 57/359 (15%), Positives = 115/359 (32%), Gaps = 44/359 (12%)

Query: 25  KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL-----TLPVDVIANPQIFSVK 79
            + VI ++K     +    K CG  L P A    +R G+        +  I    +   +
Sbjct: 31  GLDVILMEKS----SFPRDKICGDGLTPRAVGELVRMGVPTREEDGWIRNIGLRAVAGGR 86

Query: 80  TVDVAASLTRNYQRSYININRHAFDLWMKSLIPA-SVEVYHDSLCRKIWREDDKWHVIF- 137
           + +      R Y    +  +R   D  +     A   ++   +       ++    V+  
Sbjct: 87  SFEFPWPELRAYPSYGLARSRMNLDQTLAEHARASGAKLMERTNVTGPVVDERTGRVVGV 146

Query: 138 ---------RADGWEQHITARYLVGADGANSMVRRHLYPDHQIRK--YVAIQQWFAEKHP 186
                    R  G E    A  ++ ADG ++ +   L  +  + +   VA++ +F     
Sbjct: 147 TARPVDSNGRRAGEETTYRAPVVIAADGVSARMATSLGIEKAMNRPMGVAVRTYFTSPRH 206

Query: 187 VPFYSC----IFDNS-----ITNCYSWSIS-KDGYFIFGGAYPMKDGQTRFTTLKEKMSA 236
              +      ++D       +   Y W  +  DG    G               K   + 
Sbjct: 207 DDPWMESQLELWDGKPGESNLLPGYGWIFALGDGTVNVGLGSVSSTAAATKIDYKALFAR 266

Query: 237 F----QFQFGKTVKSEKCTV---LFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYA 289
           +      ++G T +++   V     P  +           L+G++ G +S  + EGI+YA
Sbjct: 267 WMENTPEEWGFTPENQIGPVRGAALPMAFNRKPLYTRGLMLVGDSGGMVSPFNGEGIAYA 326

Query: 290 LDSTDILRSVLLKQ-----PEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMR 343
           L +  +   V+ +       +    A       +  +L G     R          +MR
Sbjct: 327 LQAGRVAADVVSQATARTTDDSRERALSTYADAMSRELGGYFTLGRIFVRVIEHPRVMR 385


>UniRef50_B4WHJ4 Putative uncharacterized protein n=1 Tax=Synechococcus sp. PCC 7335
           RepID=B4WHJ4_9SYNE
          Length = 398

 Score =  176 bits (446), Expect = 1e-42,   Method: Composition-based stats.
 Identities = 57/350 (16%), Positives = 105/350 (30%), Gaps = 34/350 (9%)

Query: 20  RKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVK 79
             L+ K   + L +K         KPCGG ++P   + F  D       VI+     +  
Sbjct: 20  YHLSRKGHQVLLIEKAAL---PRYKPCGGGVSPQVAQWFDFDFEP----VISQKVTRARY 72

Query: 80  TVDVAASLTRNYQRSYININRHAFDLWMKSLIPA-SVEVYHDSLCRKIWREDDKWHVIFR 138
           T  +  ++  + +     + R+ FD ++         ++   +    +           R
Sbjct: 73  TWHLGEAIEVDLKAPIWMVRRNEFDHYLVQQAEKRGTKLLDKTKVVAVEFVSGGQTDTTR 132

Query: 139 ADG-----------------WEQHITARYLVGADGANSMVRRHLYPDHQIRKYV-AIQQW 180
            D                    +    +YL+ ADG    + + L    +      AI+  
Sbjct: 133 DDANRTDGGDQVDRWKVMTSRGETFEGQYLIAADGGRGPMAKWLGFGDRKASIAGAIEIE 192

Query: 181 FAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQ 240
              +             + N Y W+  K   +  G      D +     L   M+ +   
Sbjct: 193 PKGEVENSHVVHFEFGLLKNGYVWNFPKRDGYSIGSGVFRTDRRK-GKDLVAPMAEYASA 251

Query: 241 FG-KTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSV 299
           FG       K          +      NA L GEAA  +   + EGI  ++ +       
Sbjct: 252 FGVDGEAEPKFGHPVYIWKGNQRLHTQNAVLAGEAACVVDPLTAEGIRPSIFTGIKAAEA 311

Query: 300 LLKQPEKLNTAYWRATR------KLRLKLFGKIVKSRCLTAPALRKWIMR 343
           +        +A    T          +KL  K+ K+         + IM+
Sbjct: 312 VSDAIAGNPSALAEYTDIIAEEIGREMKLATKLAKAFYAAPYLSYRTIMQ 361


>UniRef50_C7PJY7 Geranylgeranyl reductase n=1 Tax=Chitinophaga pinensis DSM 2588
           RepID=C7PJY7_CHIPD
          Length = 415

 Score =  176 bits (446), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 57/364 (15%), Positives = 109/364 (29%), Gaps = 53/364 (14%)

Query: 20  RKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQI--- 75
            +LA   +  + +DK          K CG  L+     +  +    +   +         
Sbjct: 20  LQLAQLGIHCVVVDK----AVFPRDKVCGDGLSGKVITALNKIDPAIATRLKEANFKVNS 75

Query: 76  -FSVKTVDVAASLTRNYQRS-------------YININRHAFDLWMKS--LIPASVEVYH 119
                      SL   Y+                    R  FD ++       + + +  
Sbjct: 76  WGVTFVSPGRHSLDVGYRPDYNSSNQQHKETPIGYVCKRMDFDNFLVDEVRRRSEITLLE 135

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHL-YPDHQIRKYVA-I 177
                K   ++D ++V       +  + A  L+ A+GA+S   + +     +   YVA I
Sbjct: 136 GVTVDKYELKEDGYYVT---GSNDFKVKADLLIIANGAHSSFTKEVANITMEPEHYVAGI 192

Query: 178 QQWFAEKHP---VPFYSCIFDNSITNCYSWSIS-KDGYFIFGGAYPMKDGQTRFTTLKEK 233
           + ++          F    F   +   Y W     +G    G     +  + +   LK+ 
Sbjct: 193 RAYYKNVSGNNADNFIELHFLKDLLPGYFWIFPLPNGEANVGVGVLSEAVRKKKMNLKKS 252

Query: 234 M-------SAFQFQFGKTVKSEKCTVL-FPSRWQDFVCGKDNAFLIGEAAGFISASSLEG 285
           M         F+ +F              P   +  V   +   L+G+AA  I   + EG
Sbjct: 253 MLDIIANDPVFKERFKDAELVSSIDGYGLPLGSKQRVISGERYMLVGDAAYLIDPFTGEG 312

Query: 286 ISYALDSTDILRSVLLKQPEKLNTAYWR--ATRKLRLKLFG----------KIVKSRCLT 333
           I   L S  I      +  +  +T+  +         ++ G          K+VK   L 
Sbjct: 313 IGNGLYSGRIAALQAAEALKANDTSAAQLAKYDSEIYRILGPELKLSHRLQKLVKYPWLF 372

Query: 334 APAL 337
              +
Sbjct: 373 NTLM 376


>UniRef50_A4YEK4 Geranylgeranyl reductase n=12 Tax=Sulfolobaceae RepID=A4YEK4_METS5
          Length = 453

 Score =  175 bits (445), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 74/361 (20%), Positives = 114/361 (31%), Gaps = 25/361 (6%)

Query: 1   MEH--FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSF 58
           M+   +DV IIG G AGS  A  LA K   I L         G  KPCG  ++      F
Sbjct: 1   MKQLTYDVLIIGGGFAGSTAAWHLANKGLKILLIDSKPWNRIG-DKPCGDAVSK---EHF 56

Query: 59  IRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAF-DLWMKSLIPASVEV 117
              G+  P       +I  +K      S     +     IN  A+    ++      VEV
Sbjct: 57  DNLGMPYPEGEQLEQKIDGIKLYSPDMSTEWTVKGEGFEINAPAYTQRILREARDRGVEV 116

Query: 118 YHDSLCRKIWREDD---KWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQI--- 171
              +   K   ED       +  R    +  + A+ ++ A G +   R  L  +  +   
Sbjct: 117 MDLTTAMKPILEDGFVKGAVIFDRRKEEQIEVRAKMVIEATGYSRSFRSKLPQEIPVSED 176

Query: 172 ----RKYVAIQQ--WFAEKHPVPFYSCIFDN--SITNCYSWSISKD-GYFIFGGAYPMKD 222
                  +A ++  +  E    P Y  IF N  +    Y W   K       G       
Sbjct: 177 MDERDADIAYREVAYTREDIDEPGYLKIFINQTTSPGGYWWYFPKGKDKVNIGLGIQGGM 236

Query: 223 GQTRFTTLKEKM-SAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISAS 281
           G     T  EK    +     +     K   L P+R        +   +IG++    +  
Sbjct: 237 GYPSIYTFYEKYWKEYGADVDRNRMIVKGGALVPTRRPLDTLVWNGIIVIGDSGYTANPV 296

Query: 282 SLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRL--KLFGKIVKSRCLTAPALRK 339
              G   A+ S        L   EK + +            + +G    S  L    L+K
Sbjct: 297 HGGGKGSAMISGFCAARATLNSFEKGDFSAQSLWETNLCYNERYGAKQASLELFRRFLQK 356

Query: 340 W 340
            
Sbjct: 357 L 357


>UniRef50_D1SGH3 Monooxygenase FAD-binding n=12 Tax=Actinomycetales
           RepID=D1SGH3_9ACTO
          Length = 475

 Score =  175 bits (444), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 59/362 (16%), Positives = 109/362 (30%), Gaps = 21/362 (5%)

Query: 4   FDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           FDV ++G GP G  LA +L    + V+ L++  +      S      L   +     + G
Sbjct: 2   FDVIVVGGGPTGMMLASELRLQGVGVLVLERDAEPPPYVRSL----GLHVRSIEVMDQRG 57

Query: 63  LTLPVDVIA--NPQIFSVKTVDVAASLTRNYQRSY-ININRHAFDLWMK-SLIPASVEVY 118
           L          +P      ++D  A    +    Y + I +   D  +         E+ 
Sbjct: 58  LLERFLEHGGTHPIRGFFASIDKPAPADLDTAHPYVLGIPQTLTDRLLADHAAEVGAEIR 117

Query: 119 HDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQ-----IRK 173
             S    + ++DD   V    D     + AR+ VG DG  S VR+ L          I  
Sbjct: 118 RGSAVTGLEQDDDGVTVHL-DDESASPLRARFAVGCDGGRSTVRKLLGVGFPGEPSTIDT 176

Query: 174 YVAIQQWFAEKHPVPFYSCIFDNSITN-CYSWSISKDGYFIFGGAYPMKDGQTRFTTLKE 232
            +   +  A    +         +        S     + +   A  +         +K 
Sbjct: 177 LLGEMEVTASADEITAIMTEVRRTEKRFGLGPSGRPGVFRVVVPAADVASAPPTLDDVKR 236

Query: 233 KMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDS 292
           ++ A+             +    +            FL G+AA        +G++  +  
Sbjct: 237 QLHAYAGTDFGVHSPRWLSRFGDATRLAEHYRVGRVFLAGDAAHVHPPLGGQGLNLGIQD 296

Query: 293 T-----DILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVA 347
                  +  +V    P+ L   Y    R +   +         LT        +R  +A
Sbjct: 297 AFNLGWKLAATVNGWAPDGLLDTYETERRPVAADVLTNTRAQMLLTTNEPGPQAVRQMLA 356

Query: 348 HI 349
            +
Sbjct: 357 QL 358


>UniRef50_A8THG7 Geranylgeranyl reductase n=1 Tax=Methanococcus voltae A3
           RepID=A8THG7_METVO
          Length = 422

 Score =  175 bits (444), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 51/380 (13%), Positives = 109/380 (28%), Gaps = 47/380 (12%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
           E +DV I+G GPAG   A  +   + V+ +++    G       C GLL+          
Sbjct: 11  EQYDVIIVGGGPAGFITAENIQKDLNVLVVEEHQSIG---VPIQCAGLLSKKGFNEL--- 64

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLI---------- 111
               P  ++   +  ++       ++  + +   +   R   D  +              
Sbjct: 65  --GNPKGIVNKVRGANIFCEKQNLTVGDDNKIRAMVFERKEMDKDIAKRALKNKNVNLML 122

Query: 112 PASVEVYHDSLCRKIWREDDK-----------WHVIFRADGWEQHITARYLVGADGANSM 160
            +  ++ +++   K  +                 V       +   + + +VGADG  S 
Sbjct: 123 KSHGKILNETTTNKNNKNSKNSKNNSLNKKHIIEVKNNLKDEKYIFSPKIIVGADGVRSG 182

Query: 161 VRRHLYPDHQIRKYVAIQQWFAEKH--PVPFYSCIFDNSI-TNCYSWSISKDGYFIFGGA 217
           + + L    +      +Q  +         F +  +D    +N ++W I      +  G 
Sbjct: 183 IGKSLKMHQKREIITGVQIEYVNVSNIDSDFVNVFYDKRYSSNFFTWIIPTGKDRVRVGM 242

Query: 218 YPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGF 277
              KD   +           +         E      P  +       +N  L+G+A   
Sbjct: 243 CDTKDALNKLNNFIATNENAKEILKGATPIEYSIGAIPLGYNSKS-VLNNVMLVGDAVNQ 301

Query: 278 ISASSLEGISYALDSTDILRSVLLK--------------QPEKLNTAYWRATRKLRLKLF 323
           +   S  G+ +      +  + + +                      Y    +    K  
Sbjct: 302 VKPLSGGGLYFGAKCAKLCANTINEYYTKYHTKFLNEENANLDYLKTYEELWKSEIGKEI 361

Query: 324 GKIVKSRCLTAPALRKWIMR 343
              +K   L      K I +
Sbjct: 362 NYGLKMSYLMNKLNNKKIDK 381


>UniRef50_Q095S4 Pentachlorophenol 4-monooxygenase n=5 Tax=Bacteria
           RepID=Q095S4_STIAU
          Length = 515

 Score =  174 bits (443), Expect = 3e-42,   Method: Composition-based stats.
 Identities = 60/356 (16%), Positives = 107/356 (30%), Gaps = 43/356 (12%)

Query: 6   VAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           V I G GP G  LA +LA +      +DK  +       K     L P     F   G+ 
Sbjct: 9   VLIAGAGPTGLTLACELARRGVHFRIIDKAPEPFAGSRGK----GLQPRTLEIFEDLGVL 64

Query: 65  L----------PVDVIANPQIFSVKTVDVAASLTRNYQRS-YININRHAFDLWMKSL-IP 112
                      P+   A   +     +      +          + +   +  ++     
Sbjct: 65  DAVLAAGMPYPPLRAYAEGAVVWEGHMHEHREPSPEVPYPNPWMLPQARTERILRERLAE 124

Query: 113 ASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIR 172
           + V+V   +    + ++ +         G  Q + ARYLVGADG  S VR+ L    +  
Sbjct: 125 SGVQVEFATELTALEQDAEGVTATLLHAGQPQQVRARYLVGADGGRSFVRKQLGVGFEGE 184

Query: 173 KYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGA-----------YPMK 221
              + +    +                  ++W          G              P+ 
Sbjct: 185 TRESDRMLIGDVQVDGLDRAY-------WHTWPKPGTRTLRLGLCPLPGTNLFQFMAPLG 237

Query: 222 DGQTRFTTLKEKMSAFQFQFGKTVKSEKC----TVLFPSRWQDFVCGKDNAFLIGEAAGF 277
             +    +L+     F    G++          ++   +          N FL G+AA  
Sbjct: 238 PDEVPELSLESLQKRFDSGSGRSDIRLHGLNWLSLYRVNIRLVDRYRTGNVFLAGDAAHV 297

Query: 278 ISASSLEGISYALDSTDI----LRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKS 329
            S +  +G++  +         L  VL   PE L  +Y    R +   + G   K 
Sbjct: 298 HSPAGGQGLNTGVQDAYNLGWKLGQVLAGAPEALLDSYEEERRPIAANVLGLSTKL 353


>UniRef50_Q9CA67 Geranylgeranyl diphosphate reductase, chloroplastic n=216
           Tax=cellular organisms RepID=CHLP_ARATH
          Length = 467

 Score =  174 bits (443), Expect = 3e-42,   Method: Composition-based stats.
 Identities = 59/348 (16%), Positives = 111/348 (31%), Gaps = 35/348 (10%)

Query: 21  KLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKT 80
            LA       L ++         KPCGG +       F    L +    +   ++ S   
Sbjct: 73  TLAQGGIETILIERKMDNC----KPCGGAIPLCMVGEFN-LPLDIIDRRVTKMKMISPSN 127

Query: 81  VDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLCRKIWREDD--------- 131
           + V    T         + R   D +++     S     + L  K+   ++         
Sbjct: 128 IAVDIGRTLKEHEYIGMVRREVLDAYLRERAEKSGATVINGLFLKMDHPENWDSPYTLHY 187

Query: 132 -KWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEKHPVPFY 190
            ++     A G ++ +    ++GADGANS V + +         +A Q+          Y
Sbjct: 188 TEYDGKTGATGTKKTMEVDAVIGADGANSRVAKSIDAGD-YDYAIAFQERIRIPDEKMTY 246

Query: 191 ------SCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKT 244
                   + D+   + Y W   K  +   G       G  +   L  +  A     G  
Sbjct: 247 YEDLAEMYVGDDVSPDFYGWVFPKCDHVAVGTGTVTHKGDIKKFQLATRNRAKDKILGGK 306

Query: 245 VKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQ- 303
           +   +     P   +     K    L+G+AAG+++  S EGI +A  S  +    +++  
Sbjct: 307 IIRVEA-HPIPEHPRPRRLSK-RVALVGDAAGYVTKCSGEGIYFAAKSGRMCAEAIVEGS 364

Query: 304 -------PEKLNTAYWRATRKLR---LKLFGKIVKSRCLTAPALRKWI 341
                   E     Y     K      ++   + K    + PA   ++
Sbjct: 365 QNGKKMIDEGDLRKYLEKWDKTYLPTYRVLDVLQKVFYRSNPAREAFV 412


>UniRef50_A3DPJ1 Geranylgeranyl reductase n=2 Tax=Desulfurococcaceae
           RepID=A3DPJ1_STAMF
          Length = 458

 Score =  174 bits (443), Expect = 3e-42,   Method: Composition-based stats.
 Identities = 62/362 (17%), Positives = 115/362 (31%), Gaps = 34/362 (9%)

Query: 3   HFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            +DV ++G G AG   A  LA     V  ++ K    +    K CG  +       F   
Sbjct: 2   KYDVIVVGAGVAGLNAAFVLASKGFNVAIIESK--PRSRIGDKTCGDAI---GVHHFKEL 56

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDS 121
           G   P +   + +   VK    +   +       +++NR  F  W+      +  V  D 
Sbjct: 57  G-WYPPEETIDHRYKGVKIYSPSEKYSIIVSGEGVSVNRLKFGQWLLKRAEDNGAVLLDK 115

Query: 122 LCR-KIWREDDKW---HVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQI------ 171
                +   D+      V        + + A   +   GA   +R  L  +  I      
Sbjct: 116 HVLLGVKFNDNGIQSIKVKELGKPGLKELVADAFIDTSGAKPALRSKLPLEWPISERPYM 175

Query: 172 -RKYVAIQQWFAEKHPVPF----YSCIFDNSI--TNCYSWSISK---DGYFIFGGAYPMK 221
               +A ++      PV      Y+ I+ N+I     Y W   K         G      
Sbjct: 176 TDYNIAYREVLEINEPVNDEDVDYAVIYLNTIIAPGGYWWFFPKNPSGKIVNVGLGVVWG 235

Query: 222 -DGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISA 280
            D         + +   + +F   +       + P+R         N  + G+AA  ++ 
Sbjct: 236 VDDYNPRHNYNKYL---KPRFKGKL-LHAGGGMVPTRRPLPTLVWRNVGVAGDAAYTVNP 291

Query: 281 SSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATR--KLRLKLFGKIVKSRCLTAPALR 338
               GI  +L ++ I+   +    EK         +  K  ++ +G    +  +    L+
Sbjct: 292 VHGGGIGSSLQASAIVAKYIGDALEKGIVDETTTWQANKEYMQAYGAKQAALDILRMYLQ 351

Query: 339 KW 340
           K 
Sbjct: 352 KL 353


>UniRef50_Q24QW7 Putative uncharacterized protein n=1 Tax=Desulfitobacterium
           hafniense Y51 RepID=Q24QW7_DESHY
          Length = 430

 Score =  174 bits (443), Expect = 3e-42,   Method: Composition-based stats.
 Identities = 58/346 (16%), Positives = 106/346 (30%), Gaps = 41/346 (11%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
             FDV I+G GPAGS+ A   A   ++V+ +++    G +  +   GG+L        I 
Sbjct: 3   NKFDVIIVGAGPAGSSAAIMAAQAGLKVLVIERGEYVGAKNMT---GGMLLSQVLNEVIP 59

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRN--------YQRSYININRHAFDLWMKSLIP 112
           +       +        +       SLT +           +  ++ RH FD W+     
Sbjct: 60  EF-WKEAPLQRPVVSQRIMMTSGGRSLTVDIGNRKFSEPPFNGFSVLRHEFDAWLADKAR 118

Query: 113 ASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIR 172
            +  V                 V  +    E  +    ++ ADG NS++ R        +
Sbjct: 119 EAGAVLVTGTVVDDVIHAGNRIVGVKTRRDEGDVYGDIVILADGVNSLLARKAGLRKPYQ 178

Query: 173 --------------KYVAIQQWFAEKHPVP---FYSCIFDNSITNCYSWSISKDGYFIFG 215
                             I + F               F   I     +  +       G
Sbjct: 179 AHDIGLGVKELLDLPAKTINERFGLTGNNGAALMAIGDFARGIPGG-GFLYTNKESISLG 237

Query: 216 GAYPMKDGQTRFTTLKEKMSAFQ------FQFGKTVKSEKCTVLFPSRWQD--FVCGKDN 267
                +    +  T  E +  F+               E    L P    +       D 
Sbjct: 238 MVLQPQALIDQKLTPDEVLERFKAVPEVARLLEGAKLIEYSAHLIPEGGYNSMPKLWADG 297

Query: 268 AFLIGEAAGFI--SASSLEGISYALDSTDILRSVLLKQPEKLNTAY 311
             + G+AAGF+  +  +L+G++ A+ S        +K  +K + + 
Sbjct: 298 ILVAGDAAGFVVNTGITLQGMNLAIASGKCAGEAAVKAYQKKDFSA 343


>UniRef50_A3V9M1 Geranylgeranyl reductase n=1 Tax=Rhodobacterales bacterium HTCC2654
           RepID=A3V9M1_9RHOB
          Length = 394

 Score =  174 bits (442), Expect = 4e-42,   Method: Composition-based stats.
 Identities = 72/362 (19%), Positives = 133/362 (36%), Gaps = 24/362 (6%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           + FDV +IG GPAGS+ A++     + V  +D+          K CG L++P   ++  R
Sbjct: 4   QDFDVVVIGAGPAGSSAAKRARDLGLSVALIDR----AVFPRPKLCGALISPRGNKAVKR 59

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEV-YH 119
                    +           D       +         R  FD W++    A+  V   
Sbjct: 60  VFDMEMSPEMYLVSRQVAFKWDGEELNRFDAPYDLTYTYRLDFDHWLQQAAVAAGAVDMQ 119

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPD--HQIRKYVAI 177
            +    I   D+   +        + I  + L+GADGA S V +H+        +   A 
Sbjct: 120 GTRVETIHDADNLLEL-----SDGRRIGYKVLIGADGAASPVAKHILGAAYDPDKIGFAF 174

Query: 178 QQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAF 237
           +              I  + +   Y W+  K G    G        ++    LK +M+ +
Sbjct: 175 ETEAPGGCDPEALMSIDFDIVHWGYGWNFPKAGSRTIGLGA----IRSVDQDLKARMARY 230

Query: 238 QFQFGKTVKSEKC-TVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDST--- 293
               G    S        P        GK N  L G+AAGF+   + EGI+ A++S    
Sbjct: 231 LAHEGVDPDSVTIKGAHIPLGDFKEKPGKGNVLLAGDAAGFVDGITGEGIALAIESGAEA 290

Query: 294 -DILRSVLLKQ-PEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAHIPQ 351
            +    V+ +  P++ + AY+   + ++  L  K+ + R +   +  + + +  +     
Sbjct: 291 AEAAAQVIDEGRPQRADRAYFPRIKYIQTDL-EKVRRLRVIAYSSAMRDLFKEKLRTSTM 349

Query: 352 LK 353
           ++
Sbjct: 350 MR 351


>UniRef50_A2BM78 Predicted Dehydrogenase n=1 Tax=Hyperthermus butylicus DSM 5456
           RepID=A2BM78_HYPBU
          Length = 454

 Score =  174 bits (441), Expect = 5e-42,   Method: Composition-based stats.
 Identities = 59/369 (15%), Positives = 118/369 (31%), Gaps = 28/369 (7%)

Query: 3   HFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            +DV + GLGPAGS     LA    +V+ +++      + +SKPCG  L           
Sbjct: 6   RYDVIVAGLGPAGSVALWHLARMGFRVLGIERNR--PEKLWSKPCGDALGAH---HITES 60

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVYHD 120
            L  P   +   ++ ++     +  +          I+R AF  W+ +  +    EV ++
Sbjct: 61  HLPEPPSSVLKNRVTAIDIYSPSEEVRYRVHGKGYIIDRTAFGRWLVEDALNRGAEVLYE 120

Query: 121 SLCRKIWREDDKW-HVIFRA-DGWEQHITARYLVGADGANSMVRRHLYPDHQI------- 171
           +   +      K   V  ++ DG    + A  ++ A G + ++RR L  D  I       
Sbjct: 121 TSILEPIISGGKVIGVKAKSKDGRVVELYASLVIEATGFSRVIRRRLPRDWPIYEDIDPR 180

Query: 172 RKYVAIQQWFAEKHPVPFYSCIFD-----NSITNCYSWSISKDGYFIFGGAYPMKD--GQ 224
              +A ++    +        +             Y W   +  +    G          
Sbjct: 181 DTNIAYREIIEYEDYEIEEPNVIRIYLNQEIAPGGYWWFFPETSHRSNVGLGVQGGMGYP 240

Query: 225 TRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLE 284
           +     +EK+        K           P+R            +IG+A   ++     
Sbjct: 241 SPMQIYREKLVEHSLLRLKHRVITAAGAPLPTRRPSNTMVGPGVVVIGDAGYTVNPIHGG 300

Query: 285 GISYALDSTDILRSVLLKQPEK--LNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWI- 341
           G+ Y   +         +   K   +     +     ++  G    S  +    L++   
Sbjct: 301 GMGYGFRAAYYAAKAFEEAYNKGRFDEEALWSLNTSYMRSIGAKQASLDVFRRFLQRLGN 360

Query: 342 --MRSGVAH 348
             +  G+ H
Sbjct: 361 DDIEFGMKH 369


>UniRef50_C6CUN6 Monooxygenase FAD-binding n=1 Tax=Paenibacillus sp. JDR-2
           RepID=C6CUN6_PAESJ
          Length = 395

 Score =  174 bits (441), Expect = 6e-42,   Method: Composition-based stats.
 Identities = 65/366 (17%), Positives = 118/366 (32%), Gaps = 23/366 (6%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           M  +DV ++G GP+GSA A+ LA     I +            KPCG  L P A  +  R
Sbjct: 1   MNSYDVIVVGAGPSGSASAKMLAASGVRILMLDAE---AFPRRKPCGESLNPGAVAALGR 57

Query: 61  D----GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYINI--NRHAFDLWMKSLIPAS 114
                 +    D  ++P     K     ASL   Y   +  +   R   DLW+      +
Sbjct: 58  ITGYSHVQEAFDFTSSPI-QGWKVSSGRASLEAVYPEGHYGVGCRREQVDLWLAEQASRA 116

Query: 115 VEVYHD-SLCRKIWREDDKWHVIFRA--DGWEQHITARYLVGADGANSMVRRHLYPDHQI 171
             V+   +   ++  E ++   +     +G    I A  ++G+DG  S+V R+   +   
Sbjct: 117 GAVFEQRTKVERLIWEGERVAGVIARSPEGKPMSIRASLVIGSDGLRSVVARNAKVNRYG 176

Query: 172 R-KYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFI--FGGAYPMKDGQTRFT 228
             +  A          +     +F          +    G                    
Sbjct: 177 SLRKAAFTARLNGVRGLNGRVELFTAGEGKVIGLAPIGAGLANMTVVLGSAKAASLADKD 236

Query: 229 TL------KEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASS 282
            L         +     +       +      P              L+G+AAG+    +
Sbjct: 237 RLGIVLREARAVPELTERLRDAEIEDGVLACGPFDRPVIPHDIAGMVLLGDAAGYYDPLT 296

Query: 283 LEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIM 342
            +GI  AL S ++    +++  +  +    R  R   L  F    + + +     R  ++
Sbjct: 297 GQGIYRALRSAELAAPAIVQTLQTRDPDPLRQYRIANLAEFATGTRLQHIIERLTRHPLL 356

Query: 343 -RSGVA 347
            RS + 
Sbjct: 357 WRSALR 362


>UniRef50_C8SW54 Monooxygenase FAD-binding n=1 Tax=Mesorhizobium opportunistum
           WSM2075 RepID=C8SW54_9RHIZ
          Length = 413

 Score =  173 bits (440), Expect = 6e-42,   Method: Composition-based stats.
 Identities = 70/394 (17%), Positives = 110/394 (27%), Gaps = 50/394 (12%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
             D  +IG GPAG++ A  LA     +A+ +K         K CG  ++        R  
Sbjct: 6   THDAIVIGAGPAGTSAALTLARHGWSVAIVEKS---AFPRRKVCGEYISASNLVLLDRLE 62

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYIN---------INRHAFDLWMKSLIP- 112
           +       A P+I  V        +      +            + R   D  +      
Sbjct: 63  IGDAWRADAGPEIRRVGFFSGETCVEAPMPDAKYGPAKDGFGRALGRDILDALLLQAARS 122

Query: 113 ASVEVYHDSLCRKIWREDDKWHVIFRADGW-----EQHITARYLVGADGAN--SMVRRHL 165
           A  +++       I R+ D   V  +A G         + A  ++ A G+     +   L
Sbjct: 123 AGAQIFQPCRAVAIDRDGDMQRVRIQARGENSGDETTTLRAPVIIAAHGSWEPGSLPSQL 182

Query: 166 YPDHQIRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKD-GYFIF---------- 214
              +     +  +  F      P    +   +    Y   +  D G              
Sbjct: 183 EKINHPSDLLGFKAHFTGSTLAPDLMPLL--AFPGGYGGMVLADHGRLSISCCIRREMLA 240

Query: 215 -----------GGAYPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVC 263
                      G A P+      F  L                  +     P R     C
Sbjct: 241 RLRGKHGSGHDGVASPVSAADVVFHHLMASCRGVSDALDGACLDGRWLAAGPIRPGIRAC 300

Query: 264 GKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQP------EKLNTAYWRATRK 317
            + + F +G AAG       EGIS AL S  +L   L   P      E     Y  A R 
Sbjct: 301 YERDIFRVGNAAGESHPIIAEGISMALQSGWLLARELSGAPSGRAGREAAGRRYQAAWRG 360

Query: 318 LRLKLFGKIVKSRCLTAPALRKWIMRSGVAHIPQ 351
           L             +        +M + V + PQ
Sbjct: 361 LFSTRVHAAAAIARIALGPGGPLLMAAAVRNFPQ 394


>UniRef50_Q9AL91 Alkylhalidase CmlS n=3 Tax=Actinomycetales RepID=Q9AL91_9ACTO
          Length = 577

 Score =  173 bits (440), Expect = 7e-42,   Method: Composition-based stats.
 Identities = 52/316 (16%), Positives = 95/316 (30%), Gaps = 38/316 (12%)

Query: 6   VAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           VAIIG GPAGS     L      V   ++          +  G  L P       R GL 
Sbjct: 6   VAIIGGGPAGSVAGLTLHKLGHDVTIYERSA----FPRYRV-GESLLPGTMSILNRLGLQ 60

Query: 65  LPVDVIANPQIFSVKTVDVAASLTRNYQRSY-----------ININRHAFDLWMK-SLIP 112
             +D     +  S   +         +  +            + + R  FD  +      
Sbjct: 61  EKIDAQNYVKKPSATFLWGQDQAPWTFSFAAPKVAPWVFDHAVQVKREEFDKLLLDEARS 120

Query: 113 ASVEVYHDSLCRKIW-REDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQI 171
             + V+ ++    +   + D+  +  R  G    + + +++ A G+   + R L      
Sbjct: 121 RGITVHEETPVTDVDLSDPDRVVLTVRRGGESVTVESDFVIDAGGSGGPISRKLGVRQYD 180

Query: 172 RKY--VAIQQWFAEKHPVPFY--SCIFDNSITNCYSWSIS-KDGYFIFGGAYPMKDGQTR 226
             Y   A+  +F  K P         +  +  + + W I  KD  +  G           
Sbjct: 181 EFYRNFAVWSYFKLKDPFEGDLKGTTYSITFEDGWVWMIPIKDDLYSVGLVVDRSKSAEV 240

Query: 227 FTT--------LKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFI 278
                         K +      G   + ++  ++    +   V   D  FL G+AA F 
Sbjct: 241 REQGADAFYSSTLAKCAKAMDILGGAEQVDEVRIVQDWSYDTEVFSADRFFLCGDAACFT 300

Query: 279 SA------SSLEGISY 288
                      +G+  
Sbjct: 301 DPIFRRSVLFSQGVHL 316


>UniRef50_C6VW94 Tryptophan halogenase n=1 Tax=Dyadobacter fermentans DSM 18053
           RepID=C6VW94_DYAFD
          Length = 415

 Score =  173 bits (440), Expect = 8e-42,   Method: Composition-based stats.
 Identities = 51/344 (14%), Positives = 111/344 (32%), Gaps = 28/344 (8%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M+  DV +IG GPAG+  A  L      V  L+K+            G  L P       
Sbjct: 1   MQTVDVLVIGAGPAGTVAASYLKKQGYDVTILEKEK----FPRF-QIGESLLPCCMEHLT 55

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSY-------ININRHAFDLWMKSL-I 111
             GL   ++ +   +      +         ++  +         + R  FD  +     
Sbjct: 56  EAGLREAIEPLNFQKKTGAAFMRGEKRCEFFFEDQFTKGWTWTWQVKRADFDSKLAEATR 115

Query: 112 PASVEVYHDSLCRKIWREDDKWHVIFR-ADGWEQHITARYLVGADGANSMVRRHLYPDHQ 170
              V+V  +     +    +K  V ++ A+G    I A++++ + G   ++ R       
Sbjct: 116 EKGVDVNFECEVTAVECGPEKQIVDYKDAEGNAHRIEAKFIIDSSGYGRVLPRLFNLSKA 175

Query: 171 IR--KYVAIQQWFAEKH-PVPFYSCIFDNSITN--CYSWSIS-KDGYFIFGGAYPMKDGQ 224
                  A+     +K+      + IF +S  N   + W+I   DG    G     +  +
Sbjct: 176 SAFTPRGAVFSHLEDKNRSEEASNNIFVHSFDNNKSWIWAIPFSDGSTSVGIVGDREKIE 235

Query: 225 T-------RFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGF 277
                   ++       +    +F ++    +   +            +   L G +  F
Sbjct: 236 ALAENNGEQYKEFIRNFADLNGRFKESDFKFEPRAILGYSIGVTQMSGEGFVLSGNSTEF 295

Query: 278 ISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLK 321
           +      G+++A  S  +   +  K  +     + +   ++  +
Sbjct: 296 LDPIFSSGVTFATASGLLSAKMTHKHLQGEAVNWKKDYEEVIQQ 339


>UniRef50_Q82R48 Putative FAD-binding monooxygenase n=1 Tax=Streptomyces avermitilis
           RepID=Q82R48_STRAW
          Length = 525

 Score =  173 bits (438), Expect = 1e-41,   Method: Composition-based stats.
 Identities = 57/355 (16%), Positives = 111/355 (31%), Gaps = 24/355 (6%)

Query: 5   DVAIIGLGPAGSALARKL-AGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           DV IIG GP+GSALA  L    + V  +D+         +K     + P +       G 
Sbjct: 8   DVLIIGAGPSGSALAIDLVRRGLDVRIVDRSPHAFDGSRAK----GIQPRSLEVLEDLGA 63

Query: 64  TLPV----------DVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPA 113
              V           + A P     K      +       +   I +   D  + + +  
Sbjct: 64  LDDVLAGGDTYPKLGLHAGPIGVPWKMFPHKEATPDVPYPNTWLIPQFRTDRALHARLSE 123

Query: 114 -SVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHL-----YP 167
              EV       ++ +++D            + I ARY VGADG +S VR+ L       
Sbjct: 124 LGREVEFGKELTELTQDEDTVVAKVVGADGVEEIVARYAVGADGGSSAVRKQLDIGFVGT 183

Query: 168 DHQIRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYF-IFGGAYPMKDGQTR 226
             +  + + +    +      ++            +  I     F       P +     
Sbjct: 184 TDESDRVLIVDASVSGLARNRWHMWPGLGGKLIG-ACPIPDSDMFQWMIRLTPDEKPPQE 242

Query: 227 FTTLKEKMSAFQFQFGKTVKSEKC-TVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEG 285
              + +++ +        +      +V  P+       G+   FL+G+AA   + +  +G
Sbjct: 243 IGAIIDRIHSHTRNRHIQLHEIHWKSVFRPNIRLAEHYGRGRVFLVGDAAHVHTPAGAQG 302

Query: 286 ISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKW 340
           ++  +     L   L +     + A        R  +   ++         + K 
Sbjct: 303 LNTGMQDGYNLGWKLGQVLAGADPALLETYEAERQPIAAGVLGLSTEKWGGIAKL 357


>UniRef50_B1L7J1 Dehydrogenase (Flavoprotein) n=1 Tax=Candidatus Korarchaeum
           cryptofilum OPF8 RepID=B1L7J1_KORCO
          Length = 383

 Score =  173 bits (438), Expect = 1e-41,   Method: Composition-based stats.
 Identities = 64/356 (17%), Positives = 116/356 (32%), Gaps = 24/356 (6%)

Query: 4   FDVAIIGLGPAGSALARKL-AGKMQVIALDKKHQCGTEGFSKPCGGLLA-PDAQRSFIRD 61
           +D AIIG GPAGSA +  L     +VI +++  +  +      CG  +  P +       
Sbjct: 3   YDAAIIGAGPAGSAASFFLSQRGYKVIVIERSRKASS-----ICGEYVPDPSSLGIEGEV 57

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAF-DLWMKSLIPASVEVYHD 120
           G +              +        +        +I R    +  ++       +V   
Sbjct: 58  GSSYSEFFKPFVVNELRRISFKIFGRSFKVDYLGYSIKRSEMVEDRLERAQDLGADVRLG 117

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDH----QIRKYVA 176
                + RE+     +++    +    ARY++GADG  S + R L  +      +     
Sbjct: 118 ESFITLEREE-----VYKILTSKGEYFARYVIGADGFLSRISRFLNGEKVDLDDVSIAFP 172

Query: 177 IQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDG-YFIFGGAYPMKDGQTRFTTLKEKMS 235
           I+     + P        +      Y+W I +       G                + M 
Sbjct: 173 IEAELKVEDPSEMKLIFDEEVAPGAYAWIIPRGDSRANVGLGI---RCSMITMNPLDYMR 229

Query: 236 AFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDI 295
            F    G   +  +     P         +D  FL+G+AAG +  S+  GI  A+ S  +
Sbjct: 230 KFLSILGIEARDLRGR-FVPVGGLVKRVAEDGIFLLGDAAGMVIPSNGGGIHNAIISAYL 288

Query: 296 LRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAHIPQ 351
           L   L  + E     Y     +         +  R      LR  I++  +  +P+
Sbjct: 289 LSKSL--ESELPEEKYTSYVNRYIRGDLEAGLTYRRAADVLLRLGILKKMIGLLPR 342


>UniRef50_B1YHN9 Monooxygenase FAD-binding n=1 Tax=Exiguobacterium sibiricum 255-15
           RepID=B1YHN9_EXIS2
          Length = 524

 Score =  172 bits (437), Expect = 2e-41,   Method: Composition-based stats.
 Identities = 61/372 (16%), Positives = 120/372 (32%), Gaps = 27/372 (7%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
           +  DV IIG GP G  LA  L+       + ++   G    SK  G  +   +   F R 
Sbjct: 3   KKIDVLIIGAGPTGLTLALALSRYGLTFRIIERAS-GPSVVSKAIG--IQARSLELFARL 59

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNY-----QRSYINI-NRHAFDLWMKSLIPASV 115
           G+   +   A         V+ A     ++        ++ +  +   +  +++ +    
Sbjct: 60  GVADALMENAIKINQGNLYVNGAWQAKLDFTDLNTPFPFVTLLPQSETERILETRLKEDG 119

Query: 116 -EVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKY 174
             V  ++      +         R     + + A +++GADGANS VRR L      + +
Sbjct: 120 HTVERETELTGFAQFPTFVTASIRKHDVTETVDASFIIGADGANSFVRRELGLPFSGKSF 179

Query: 175 ---VAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISK-DGYFIFGGAYPMKDGQTRFTTL 230
               A+     +         IF +        S       F   G        T  + +
Sbjct: 180 KESWALADIEVDWPLSSEEVHIFFSDH--GVIESFPLQSNLFRITGNLTNGTVPTDHSAI 237

Query: 231 KEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYAL 290
           ++ +           K    ++           G    +LIG+AA   S    +G++  +
Sbjct: 238 EDFLKNRAKVPFTLKKVHWYSMFRVHNRIIEKFGHHRIYLIGDAAHINSPVGGQGMNTGI 297

Query: 291 DSTDILRSVL-----LKQPEKLNTAYWRATRKLRL------KLFGKIVKSRCLTAPALRK 339
                L   L      K    L  +Y    R+          L  ++++        L++
Sbjct: 298 ADAMNLAWKLWCVHRFKASFPLLDSYSVERREAARGILRSTNLATELLQINVPFLLPLQE 357

Query: 340 WIMRSGVAHIPQ 351
            ++R+ +   P 
Sbjct: 358 KVIRNSLKITPL 369


>UniRef50_A1RZG7 Geranylgeranyl reductase n=1 Tax=Thermofilum pendens Hrk 5
           RepID=A1RZG7_THEPD
          Length = 423

 Score =  172 bits (437), Expect = 2e-41,   Method: Composition-based stats.
 Identities = 71/369 (19%), Positives = 125/369 (33%), Gaps = 37/369 (10%)

Query: 4   FDVAIIGLGPAGSALARKLAGK-MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +D+ ++G GPAGS+ A   A   + V+ L+K    G     K CGG ++   Q S    G
Sbjct: 2   YDLVVVGGGPAGSSAAIAAARAGLSVVVLEK----GERNRDKYCGGGISVLTQNSLRELG 57

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYIN-INRHAFDLWMKSLIPA-SVEVYHD 120
               ++   N     V  +     L           + R  FD  ++ L  +    V H 
Sbjct: 58  AAEALETFENYAEGHVLVLPGEKVLVDAIPGLGYGLVRRSVFDAKLRELAESYGATVKHG 117

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIR----KYVA 176
                I  + DK  V  R     + +  RY V A GA +   R L               
Sbjct: 118 FEASSITVDGDKVVVRSRKG---EVVEGRYAVVATGAGNFPERALGFPPLRPENLGHCWG 174

Query: 177 IQQWFAEKHPVPFYSCIF--------DNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFT 228
            +  +     V  +   +           +T  Y W   K  +   G    + +      
Sbjct: 175 TEAEYPVSAEVERWRHEYGFTPIFLMFGFVTYGYMWVFPKRNHMNVGMGTTLAESARYGR 234

Query: 229 TLKEKMSA---FQFQFGKTVKSEKCTV----LFPSRWQDFVCGKDN-AFLIGEAAGFISA 280
              E  +       + G   +  +  V    L P + +     ++    L G+AAGF+  
Sbjct: 235 LHLEGFARGLELARRMGILSEPGRLRVDRSWLIPGKPRAVTYSQERRVLLAGDAAGFVHP 294

Query: 281 SSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKI-------VKSRCLT 333
            + EGIS A+ S  +    + +  +K +    +         FG+        +     +
Sbjct: 295 LTGEGISGAVRSGRLAAETVKQALDKEDPGLLKEYEAKWWADFGEDAYAYGLKLTRLMYS 354

Query: 334 APALRKWIM 342
           +PAL++  +
Sbjct: 355 SPALQRLGL 363


>UniRef50_C3NB54 FAD dependent oxidoreductase n=12 Tax=Sulfolobaceae
           RepID=C3NB54_SULIY
          Length = 395

 Score =  172 bits (436), Expect = 2e-41,   Method: Composition-based stats.
 Identities = 59/327 (18%), Positives = 111/327 (33%), Gaps = 32/327 (9%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            FD+ ++G GPAGS+ A   A    +V+ L++    G E  SK   G +      S + D
Sbjct: 2   KFDIVVVGAGPAGSSAAITAARGGAKVLLLER----GPEPGSKNVSGAMIRLEDFSSVYD 57

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIP-ASVEVYHD 120
             ++P++         + +      ++ N + +   + R   D WM      A   +   
Sbjct: 58  IASIPIERKVKNVDLILLSNSNRTRISVNVESNLATVARLKLDKWMAQQAEKAGALLITK 117

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQ- 179
           +    + RE +++ V          + A  +V A+G N++V         +    A+Q  
Sbjct: 118 TTVLGVEREGNEYKVET----DRGEVRADRVVLAEGVNALVSMKANIRPDLTPDHAVQTV 173

Query: 180 -------------WFAEKHPVPFYSCIFDNSIT-NCYSWSISKDGYFIFGGAYPMKDGQT 225
                         F  K      S             +          G   PMK    
Sbjct: 174 KEVYSLNKDEVNKRFGFKADDEGVSWRILGIDPVPYAGFLYVYKDAVAIGAGIPMKILIK 233

Query: 226 R-------FTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFI 278
           R          +KE++   +   G +++     V+    +  +       +L G+A G +
Sbjct: 234 RKITPYTVLDEVKERLGFNELVKGASLREYSAKVIPEYGFPSWKACSGKIYLAGDAIGLV 293

Query: 279 SASSLEGISYALDSTDILRSVLLKQPE 305
              +  GI  A+ S  +     L+  E
Sbjct: 294 DPLTFNGIGPAVASGVVAGKAALESYE 320


>UniRef50_C7M500 Tryptophan halogenase n=4 Tax=Flavobacteriaceae RepID=C7M500_CAPOD
          Length = 417

 Score =  171 bits (433), Expect = 4e-41,   Method: Composition-based stats.
 Identities = 49/349 (14%), Positives = 110/349 (31%), Gaps = 33/349 (9%)

Query: 1   MEH--FDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRS 57
           M+    DV +IG GP+G   A  L    ++V  ++K             G  L P     
Sbjct: 1   MKKEVTDVLVIGAGPSGCVSAAYLHNNGVKVRVVEKTK----FPR-LVVGESLIPRVMDH 55

Query: 58  FIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSY-------ININRHAFDLWMKSL 110
           F   G    ++       +  + +        ++ + Y         + R  FD  +   
Sbjct: 56  FEEAGFMPALEAQKYEVKWGARFIRGEQVCQFDFGKKYGKGWDWTWQVPRADFDNVLAQE 115

Query: 111 I-PASVEVYHDSLCRKIWREDDKWHVIFR-ADGWEQHITARYLVGADGANSMVRRHLYP- 167
           +    V +  ++    +    D      + A+G    IT+++++ A G   ++ R L   
Sbjct: 116 VIRKGVNLTFETEVTDVQFFPDHQVTTVKDANGEVSEITSKFVIDASGYGRVLPRLLDLN 175

Query: 168 -DHQIRKYVAIQQWFAE----KHPVPFYSCIFDNSITNCYSWSIS-KDGYFIFGGAYPM- 220
              ++  + +I     E              FD      + W I   +G    G   P  
Sbjct: 176 SPSKLDDHSSIFTHIKEGKVRPAGEEGTLISFDVLEREVWLWVIPFSNGNTSVGIVGPTH 235

Query: 221 --------KDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIG 272
                    D +       ++   ++ +F  +    K   +            +   L G
Sbjct: 236 YINALSASGDTEEALRKAIKRSDFYRPRFEHSDFLFKPNKIQSYSCSVKKLFGEGFVLTG 295

Query: 273 EAAGFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLK 321
            +  F+      G+++A +S  +   ++ ++       + +   +   +
Sbjct: 296 NSTEFLDPVFSSGVAFATESGMLAAKLVKRELAGEKVDWQKEYAEYMQR 344


>UniRef50_D1X0J5 Geranylgeranyl reductase n=1 Tax=Streptomyces sp. ACT-1
           RepID=D1X0J5_9ACTO
          Length = 892

 Score =  171 bits (433), Expect = 4e-41,   Method: Composition-based stats.
 Identities = 52/318 (16%), Positives = 102/318 (32%), Gaps = 31/318 (9%)

Query: 6   VAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTL 65
           V ++G GPAGS+ A  LA     + L +K         K CG  L P A    IR G+ +
Sbjct: 464 VIVVGAGPAGSSAAYHLARAGVDVILLEKA---RFPREKVCGDGLTPRAVHQLIRMGVDI 520

Query: 66  PVDVIANPQIFSV----KTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVYHD 120
                   +          V +       Y    ++ +RH FD  + +  + A   +Y  
Sbjct: 521 TAPGWTRSRGMRWVAGEHRVRIDWPALGRYPDFGLSRSRHDFDDILARHAVAAGARLYSG 580

Query: 121 SLCRKIWREDDKWHVIFRADGWEQHI------TARYLVGADGANSMVRRHLYPDHQIRKY 174
               +   +         A      +       A  ++ ADGA++ +   L  +   R+ 
Sbjct: 581 WKAERPLTDRAGRVTGVAASSDSAEVPEPVDFHAPVVIAADGASARLALALGLERDPRRQ 640

Query: 175 VAIQQWFAEKHPVP----------FYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQ 224
           +A       + P                         Y W        +  G   +   +
Sbjct: 641 IATAARRYYRSPERSREEYLELWADLRFPGGGPYLPGYGWIFPMGDGRVNVGLGALPHRR 700

Query: 225 TRFTTLKEKMSAFQFQFGKTVKSEK-------CTVLFPSRWQDFVCGKDNAFLIGEAAGF 277
                L+  +  +  +  +     +        +   P  +           L+G++ G 
Sbjct: 701 HGKADLRATLDQWLARTPEEWGLREENAEGPVRSAALPLGFNRHPLYARGLLLVGDSGGM 760

Query: 278 ISASSLEGISYALDSTDI 295
           +S  + EGI+ A+++ ++
Sbjct: 761 VSPWNGEGIAQAMEAGEV 778


>UniRef50_C9N331 Geranylgeranyl reductase n=3 Tax=Streptomyces RepID=C9N331_9ACTO
          Length = 440

 Score =  171 bits (433), Expect = 5e-41,   Method: Composition-based stats.
 Identities = 59/365 (16%), Positives = 116/365 (31%), Gaps = 43/365 (11%)

Query: 20  RKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSV- 78
             LA     + L +K   GT    K CG  L P   +  +R G+ +        +     
Sbjct: 30  LHLARAGVDVLLLEK---GTFPRDKVCGDGLTPRGVQQLVRMGVDIDAPGWMRTKGMRWV 86

Query: 79  ---KTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVYHDSLCRKIWREDDKWH 134
              + V +    + ++    +  +RH FD  + +  + A   +  ++       +     
Sbjct: 87  CGGRQVHIDWPRSGSHPDFGLTRSRHDFDDILARHAVAAGARLCLETRATGPLTDRAGRI 146

Query: 135 VIFRA----DGWEQHITARYLVGADGANSM--VRRHLYPDHQIRKYVAIQQWFAE--KHP 186
           V   A    D   +   A  ++ ADGA++   +   L  D       A ++++    +  
Sbjct: 147 VGVSAVTGADKQPRTYRAPVVIAADGASARTALAMGLERDRGKPMATAARRYYRSEARTH 206

Query: 187 VPFYSCIFD------NSITNCYSWSIS-KDGYFIFGGAYPMK------DGQTRFTTLKEK 233
            P+     D            Y W     DG    G            D +        +
Sbjct: 207 DPYLELWADLRCSRTGRDLPGYGWIFPLGDGRVNVGLGALPHRGHGTVDLRATMDRWMAR 266

Query: 234 MSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDST 293
           M A      +  +S   +   P  +           L+G++ G +S  S EGI  A+++ 
Sbjct: 267 MPAHWELREENAESPLRSAALPMGFNRRPQYGRGLLLVGDSGGMVSPWSGEGIVQAMEAG 326

Query: 294 DILRSVLLKQP--------EKLNTAYWRATRKLRLKLFGK------IVKSRCLTAPALRK 339
           ++    +            E+    Y     +   + +        +V +R    P L +
Sbjct: 327 EVAAETVALALHRPEGPGREQALHQYASEVNRRWGRYYRLGNTVADLVFARYGYRPLLNR 386

Query: 340 WIMRS 344
            +M S
Sbjct: 387 RVMAS 391


>UniRef50_C0DS67 Putative uncharacterized protein n=2 Tax=Neisseriaceae
           RepID=C0DS67_EIKCO
          Length = 416

 Score =  170 bits (432), Expect = 5e-41,   Method: Composition-based stats.
 Identities = 59/376 (15%), Positives = 114/376 (30%), Gaps = 32/376 (8%)

Query: 1   MEHFDVAIIGLGPAGSALARKL-AGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           ++H+DV IIG GP+G+  A  L      V  ++K+H           G  L P       
Sbjct: 2   IQHYDVVIIGAGPSGAVAAALLNKRGFNVCVVEKQH----FPRF-VIGESLLPHCIELLH 56

Query: 60  RDGLTLPVDV-----IANPQIFSVKTVDVAASLTRNY---QRSYININRHAFDLWMK-SL 110
             G    V         N   FS    + +   T  +     +  N+ R  FD  +    
Sbjct: 57  EAGFLPAVQAGFGFQYKNGFAFSWGERNTSFKFTDKFSSGPSTAFNVERARFDKILIDEA 116

Query: 111 IPASVEVYHDSLCRKIWREDDKWHVIFRADGWE-QHITARYLVGADGANSMVRRHLYPDH 169
           I   V V   S  +      D   ++ + +G +   + AR+++ A G + ++ R L  D 
Sbjct: 117 IKQGVTVQFGSTVKAFDNHGDFAKLVVQQEGGDPYVLGARFVLDASGYHRVLPRMLSWDI 176

Query: 170 QIRKYVAIQQWFAEKHPVPFYSCI-------FDNSITNCYSWSIS-KDGYFIFGGAYPMK 221
                V    +   +  +   S               + + W I   +G    G     +
Sbjct: 177 PSDLPVRHVHFTHIEDHITDQSFDRNKNLVCVHPEHRDIWLWLIPFSNGRASIGVVGLPE 236

Query: 222 DG-----QTRFTTLKEKMSAFQFQFGKT-VKSEKCTVLFPSRWQD-FVCGKDNAFLIGEA 274
                           ++   +         ++   +  P            +  L+G A
Sbjct: 237 KLGQESSAVILKKFALEVPFLRRILKNAQWDNDFPFIYLPGYSASVKSLYGRHFALLGNA 296

Query: 275 AGFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTA 334
           A F+      G++ A  S  +   ++ +Q       +     +  +              
Sbjct: 297 AEFLDPVFSSGVTIATHSAKLAADLVARQLNGQQVNWQNEFARPLMSGVNVFRHYVEAWY 356

Query: 335 PALRKWIMRSGVAHIP 350
               + ++ SG    P
Sbjct: 357 SGTLQDMIFSG-QRTP 371


>UniRef50_C8SAI9 Geranylgeranyl reductase n=1 Tax=Ferroglobus placidus DSM 10642
           RepID=C8SAI9_FERPL
          Length = 377

 Score =  170 bits (431), Expect = 7e-41,   Method: Composition-based stats.
 Identities = 59/321 (18%), Positives = 112/321 (34%), Gaps = 23/321 (7%)

Query: 6   VAIIGLGPAGSALARKLAGK-MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           V ++G   AGS  A  L  +  +V+  ++    G   F   C GL++ D        G+ 
Sbjct: 17  VCVVGGRVAGSLTALNLGERDAEVVVFEEHRDSG---FPVSCAGLISEDCYERLRNFGV- 72

Query: 65  LPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLCR 124
              +   N    +         +    +   + + R   D  +        EV   S   
Sbjct: 73  ---NAKQNEIKGAFFFSPSGKYVEAIGKSRGVVVERKLMDSQLLRRASKVAEVRMSSKVV 129

Query: 125 KIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEK 184
            + R +    V F  +G E+  +   LVGADG NS+V +          ++A+Q     +
Sbjct: 130 GVERGE----VTFIVNGREKKESFDVLVGADGVNSVVAKSFGFKRPK-IFLAVQILSEFE 184

Query: 185 HPVPFYSCIFDNS--ITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFG 242
                +  ++         +++++  +      G     +       L  +  +   + G
Sbjct: 185 AIDEKFVELYFGRRYSEGFFAYAVPIEEDLAKIGVVSKTNPMVYLQRLINEHPSVSERIG 244

Query: 243 KTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLK 302
           K    E      P    D    ++N  LIG++AG +   +  GI Y L   ++L      
Sbjct: 245 KGF-LELNVGAIPIGLVD--FVRENVALIGDSAGMVKPYTGGGIYYTLIGAEVLGKTF-- 299

Query: 303 QPEKLNTAYWRATRKLRLKLF 323
                  A+ +A +K   K +
Sbjct: 300 ---PNLKAFEKAYKKRMWKEY 317


>UniRef50_UPI0001AEE709 putative oxidoreductase n=1 Tax=Streptomyces roseosporus NRRL 11379
           RepID=UPI0001AEE709
          Length = 397

 Score =  170 bits (431), Expect = 7e-41,   Method: Composition-based stats.
 Identities = 56/344 (16%), Positives = 106/344 (30%), Gaps = 28/344 (8%)

Query: 3   HFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            +DV ++G   AGS  A  LA    +V+ +D+               L+ P    +    
Sbjct: 5   RYDVIVVGARCAGSPTAMLLARKGYRVLVVDR----AVFPSDTLSTHLVHPPGVAALRGW 60

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQ----RSYININRHAFDLWMKSLI-PASVE 116
           GL   +     P I + +    +  L                R   D  +      A  E
Sbjct: 61  GLLDRLVATGCPPIHTYEFDFGSLVLPGAPGTEAEPYAYAPRRTVLDKLLVDAAREAGAE 120

Query: 117 VYHDSLCRKIWREDDKWHVIFRAD---GWEQHITARYLVGADGANSMVRRHLYPDHQIRK 173
           V        +   D    V  R     G E    AR ++GADG +S+V R +        
Sbjct: 121 VREGFTVTGLVLGDAGDVVGVRGRGPHGPEVTERARVVLGADGLHSLVARAVDAPRYNEN 180

Query: 174 YVAIQQWFAEKHPVPFYSCIFDNSIT-NCYSWSISKDGYFIFGGAYPMKDGQTRFTTLK- 231
              +  +++    +        +S     +    + DG  + GG +P  +       ++ 
Sbjct: 181 PKLMVGYYSYFSGLDMDGVFKAHSRPYRSFGAWPTHDGLTLVGGCWPFAEFNDIRKDIEG 240

Query: 232 ------EKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEG 285
                     A++ +     + ++        +           L+G+A       + +G
Sbjct: 241 NYFKNFALAPAWEERIRDARREDRIVGAALPNFFRKPF-GPGWALVGDAGYCKDFFTAQG 299

Query: 286 ISYALDSTDILRSVLLKQP------EKLNTAYWRATRKLRLKLF 323
           IS A  S ++    L          +    AY  A  +    ++
Sbjct: 300 ISDAFLSAEMCAGSLDDALSGRAPFDTAMAAYQAARDRHARPVY 343


>UniRef50_Q0R4P7 ChlB4 n=8 Tax=Bacteria RepID=Q0R4P7_STRAT
          Length = 449

 Score =  170 bits (431), Expect = 8e-41,   Method: Composition-based stats.
 Identities = 61/401 (15%), Positives = 117/401 (29%), Gaps = 54/401 (13%)

Query: 1   ME-HFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M+  FD AI+G GPAGSA+A  LA     +A+ +             G  L P       
Sbjct: 1   MQPDFDAAIVGGGPAGSAMASYLAEAGLSVAVFESEMFPRPHI----GESLVPATMPVLD 56

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSY------------------------ 95
             G+   ++    P+ +        +    +   +                         
Sbjct: 57  EIGVMPDIEAAGFPKKYGAAWTSAESRDVPHNGFTGLDHDFKAAEVMFVERDQPGVHRDY 116

Query: 96  -ININRHAFDLWMKSLIP-ASVEVYHDSLCR--KIWREDDKWHVIFRADGWEQHITARYL 151
             +++R  FDL +         +V+  +         + D   +  R        T R +
Sbjct: 117 TFHVDRGKFDLILLKHAESRGAQVFQKTRVLKADFDTDPDLVTLNCRLGPRTLDFTTRMV 176

Query: 152 VGADGANSMVRRHLYP--DHQIRKYVAIQQWFAEKHPV--------PFYSCIFDNSITNC 201
           + A G  +M+   L       +    AI  WF                Y  +    + + 
Sbjct: 177 IDASGRQTMLGNQLKVKVPDPVFNQYAIHAWFEGLDRTAMALDPAKRDYIYVHFLPLEDT 236

Query: 202 YSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKM--------SAFQFQFGKTVKSEKCTVL 253
           + W I         G    K      +  +EK                 K  +       
Sbjct: 237 WMWQIPITDTITSVGVVTQKHRFKAASADREKFFWDIVSSRKDIYDALQKAERIRPFKAE 296

Query: 254 FPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWR 313
               +       D   LIG+AA F+      G+S AL+S  +    ++      +  + +
Sbjct: 297 GDYSYAMRQICGDRFLLIGDAARFVDPIFSSGVSVALNSARLAAKDVIAAHRAGD--FRK 354

Query: 314 ATRKLRLKLFGKIVKSRCLTAPALRKW-IMRSGVAHIPQLK 353
            +     +   + V++         +  I+ +     P+ +
Sbjct: 355 ESFATYEEKLRRAVRNWYEFISVYYRLNILFTAFVQDPRYR 395


>UniRef50_Q4V217 Possible monooxygenase n=1 Tax=Bacillus cereus E33L
           RepID=Q4V217_BACCZ
          Length = 404

 Score =  170 bits (431), Expect = 8e-41,   Method: Composition-based stats.
 Identities = 61/359 (16%), Positives = 125/359 (34%), Gaps = 30/359 (8%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M+  DV I+G GP G  L+  LA   ++ + L++  +   E      G    P   + F 
Sbjct: 1   MKT-DVVIVGAGPGGCFLSYLLARSGVKTVLLERHERLDREFR----GYFFQPLVLKFFE 55

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTR-------NYQRSYININRHAFDLWMKSLIP 112
           + GL   V  I + ++ +   +D   +L               + +++     ++     
Sbjct: 56  QTGLLNDVLQIKHEKVDAFHFIDHGKTLFSVRFDELPKPYDYGLIMSQPLLLQFLIDQAL 115

Query: 113 A--SVEVYHDSLCRKIWREDDKW-HVIFRADGWEQHITARYLVGADGANSMVRRHLYPDH 169
              +   +  ++ ++  +E++K   +  +    E  I +R +VGADG  S +R+      
Sbjct: 116 QYDNFSYFSGTIAKEFIKEENKIAGIKAKQKKQEIIIESRLVVGADGRYSTIRKLAGIPL 175

Query: 170 QIRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKD-GYFIFGGAYPMKDGQTRF- 227
               +     WF                        I K  G    G             
Sbjct: 176 DKESHQFDFVWFDMPALEGKRYLPHIQIEDEGMLIYIPKGSGVVQVGWVIRKGTYPDLRK 235

Query: 228 ---TTLKEKMSAFQFQFGKTVKSE-----KCTVLFPSRWQDFVCGKDNAFLIGEAAGFIS 279
                 ++++ A   +  + +        +C+VL           +D   LIG+AA   S
Sbjct: 236 KGIEYFQKQLIAVDPELEQQLSVYLHDFKQCSVLDIQVATSNQWVQDGLMLIGDAAHIAS 295

Query: 280 ASSLEGISYALDSTDILRSVLLKQPEKLNTAYW----RATRKLRLKLFGKIVKSRCLTA 334
             S +G S A+    +   V++K   ++ ++      +    +R     +I K + + A
Sbjct: 296 PFSGQGNSLAIQDAVVAHDVIMKALPQVQSSLAMHLLKQYEDIRRPAVSQIQKIQRIQA 354


>UniRef50_O26821 Conserved protein n=1 Tax=Methanothermobacter thermautotrophicus
           str. Delta H RepID=O26821_METTH
          Length = 375

 Score =  169 bits (430), Expect = 9e-41,   Method: Composition-based stats.
 Identities = 69/345 (20%), Positives = 113/345 (32%), Gaps = 39/345 (11%)

Query: 1   MEHFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M  +DV I+G GPAGS LAR  A    +V   ++K   G       C GL++       +
Sbjct: 1   MTDYDVLIMGAGPAGSTLARLTATKGFRVGLFERKKIIG---LPLQCAGLVSHRIMEVNV 57

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRS-YININRHAFDLWMKSLI-PASVEV 117
                LP + I N    +V        L  +  R     I+R A+D  +  L   A  E+
Sbjct: 58  -----LPDEFILNSVRGAVLHSPSGIKLRVSKDRPEAHVIDRTAYDQHLAELAMEAGAEL 112

Query: 118 YHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAI 177
              +  R    +     V          ++A  LV A G ++             +Y A 
Sbjct: 113 TKGTAVRDFNEKTGHVRV------NGDELSADVLVDARGQSAA----------PSRYPAR 156

Query: 178 QQWFAEKHPVPFYSCI---FDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKM 234
           Q     +        +    D+ ++  + W I  D      G +           LKE +
Sbjct: 157 QYLVRFRDSEMDTDFVDLKVDSRLSPGFMWRIPIDEQTARVGVFG------PQQNLKEFL 210

Query: 235 SAF-QFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDST 293
             F           E      P    D    +    L+G+AAG +  ++  GI  A  + 
Sbjct: 211 KGFISDLSSDFEILESHHGFIPRPDLDLRLVRGRCILLGDAAGQVKPTTGGGIVLASRAA 270

Query: 294 DILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALR 338
            +   V+    E       +       K+    +K++       R
Sbjct: 271 GVAAEVIQGVLEGDAD--LKEYEDACRKIHMSEMKNQMRVQRTFR 313


>UniRef50_C7PZI2 Tryptophan halogenase n=2 Tax=Actinomycetales RepID=C7PZI2_CATAD
          Length = 506

 Score =  169 bits (429), Expect = 1e-40,   Method: Composition-based stats.
 Identities = 55/359 (15%), Positives = 111/359 (30%), Gaps = 33/359 (9%)

Query: 5   DVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           +V ++G GPAGS  A  LA     + L ++            G  +    +      G  
Sbjct: 20  EVIVVGGGPAGSTAAALLAKNGVSVTLLEREAFPRYHV----GESITYSCRGVLDYIGAL 75

Query: 65  LPVDVIANPQIFSV-----KTVDVAASLTRNYQRS--YININRHAFDL-WMKSLIPASVE 116
             ++     +   V     + +D A   T  +        ++R  FD   ++       +
Sbjct: 76  EKIEARGYTRKTGVLLRWGQELDWAIDWTAQFGPDVRSWQVDREDFDQVLLQHAAECGAQ 135

Query: 117 VYHDSLCRKIWREDD---KWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQ--- 170
           V   +  +++  ED          +     Q   A  ++ A G   ++    + D +   
Sbjct: 136 VLEQAQVKRVVFEDGRAVGVEWTPQGHSEPQITRADLVLDASGRAGLISAQHFRDRRATE 195

Query: 171 IRKYVAIQQWFAEKHPVPFYS--CIFDNSITNCYSWSIS-KDGYFIFGGAYPMK---DGQ 224
           I + VAI  ++     +P      I   S    + W I      F  G         + +
Sbjct: 196 IFRNVAIWGYWDGGELLPDSPSGSINVISSPEGWYWVIPLSGNRFSVGYVTHKSVFVERR 255

Query: 225 TRFTTLKEKMSA-------FQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGF 277
             + TL + ++A             K        V     +          FL+G+AA F
Sbjct: 256 KDYDTLDDMLAAVVAESPTVSEAMAKGTVRPGARVEQDFSYAADSFCGPGHFLVGDAACF 315

Query: 278 ISASSLEGISYALDSTDILRSVLL--KQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTA 334
           +      G+  A+ S  +  + +L  +  +   T  +          + ++        
Sbjct: 316 LDPLLSTGVHLAIYSGLLAAASVLSIENGDVTETEAYAFYESRYRNSYERLFTLVAGFY 374


>UniRef50_D0LR77 Monooxygenase FAD-binding protein n=1 Tax=Haliangium ochraceum DSM
           14365 RepID=D0LR77_HALO1
          Length = 503

 Score =  169 bits (428), Expect = 1e-40,   Method: Composition-based stats.
 Identities = 64/370 (17%), Positives = 120/370 (32%), Gaps = 27/370 (7%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQ-VIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M   DV ++G GPAG  LA  LA   + V  L++               ++ P       
Sbjct: 1   MRQADVIVVGAGPAGLTLAGDLARLGRTVTVLERWPTINPASR----AFVVMPRTMEVLD 56

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYINI--NRHAFDLWMKSLIP-ASVE 116
             G+   +  I           D    L+R   R    +   +   D  ++     +  +
Sbjct: 57  SRGIAEHLLAIGRRAASVNLFGDATVELSRVDSRYAFGLITPQTNVDAALEEYARTSGAD 116

Query: 117 VYHDSLCRKIWREDDKWHVIFRADGWEQH--ITARYLVGADGANSMVRRHLYPDHQIRKY 174
           +   +      ++ +   V  +  G   H    ARYLVGADGA+S VR  L  D   +  
Sbjct: 117 IVRGTEVIGFEQDAEGVSVQAQPKGGGAHSRWRARYLVGADGAHSTVRSLLGVDFPGKSV 176

Query: 175 VAIQQWFAEKHPV-PFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMK------DGQTRF 227
           +        +    P    +   +    + + +       +      +      D     
Sbjct: 177 LHSVVLADIRLERGPEERVLTLGNTPRVFGFLVPYAEQGWYRTLVWDRQHQVADDVPVED 236

Query: 228 TTLKEKM-SAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGI 286
             ++  +  A     G      +       R Q      D   L+G+AA   S +  +G+
Sbjct: 237 EEIERVLAEAMGRDLGVAEIRWRSRFHCDER-QVAEYRHDRVLLVGDAAHVHSPAGGQGM 295

Query: 287 SYALDSTDILRS----VLLKQPEKLNTAYWRATRKLRLKLF---GKIVKSRCLTAPALRK 339
           +  +     L       L   PE +  +Y R    +  ++    G ++++  L  P   +
Sbjct: 296 NTGIQDAVNLAWKLDLALGGAPEVVLDSYQRERHPIGRRVLMQSGAMLRAVTL-EPRAAR 354

Query: 340 WIMRSGVAHI 349
           W+    V  +
Sbjct: 355 WLRDRVVPRV 364


>UniRef50_B8FXK4 Electron-transferring-flavoprotein dehydrogenase n=6 Tax=Bacteria
           RepID=B8FXK4_DESHD
          Length = 432

 Score =  169 bits (428), Expect = 2e-40,   Method: Composition-based stats.
 Identities = 60/353 (16%), Positives = 117/353 (33%), Gaps = 42/353 (11%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            ++V IIG G AG + A KLA    +V+ +++    G++  S   GG+L        I D
Sbjct: 5   KYEVIIIGAGLAGLSAAYKLAKAGMEVVVVERGDYPGSKNLS---GGVLYSRILDQLIPD 61

Query: 62  G-LTLPVDVIANPQIFSVKT------VDVAASLTRNYQRSYININRHAFDLWMKSLI-PA 113
                P++      + ++ T      ++           + + + R  FD W+      A
Sbjct: 62  FWEEAPIERYITNYLTTLMTPTDYVNIEYKDQELAKPPYNAVTVLRAKFDRWLAEKAEEA 121

Query: 114 SVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRK 173
              +       K+ +E  +   I   D   + + A  ++ ADG NS + +      +I  
Sbjct: 122 GAMIVTGVKVDKVLKEGGRITGITTGD---EEMLADVVIAADGINSFIAQEAGLRGEIEP 178

Query: 174 YV--------------AIQQWFAEKHPVPFYSCIFDNSITN--CYSWSISKDGYFIFGGA 217
                           AI++ F  +        +  ++        +  +       G  
Sbjct: 179 AHLAVGAKALIELPQQAIEERFRLEGNEGTAYAMLGDATHGVAGGGFFYTNRESLSIGVV 238

Query: 218 YPMKDG----QTRFTTLKEKMSA--FQFQFGKTVKSEKCTVLFPSRWQDFVC---GKDNA 268
             + D        F  L + +              +E    L        V      D  
Sbjct: 239 MRLDDLVKEKVKPFEVLDDLLRHPLVAPLVKDGTMTEYGAHLTAEGGVHMVPSQLHTDGM 298

Query: 269 FLIGEAAGFI--SASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLR 319
            ++G+AAGF   S   + G+  A+ S       +L+  E+ + +    +   R
Sbjct: 299 LIVGDAAGFTINSGLVIRGMDLAIGSGMAAAEAVLEAKERGDYSAAALSSYQR 351


>UniRef50_Q4ZTV6 Flavoprotein monooxygenase:Monooxygenase, FAD-binding n=3
           Tax=Pseudomonas syringae group RepID=Q4ZTV6_PSEU2
          Length = 553

 Score =  169 bits (428), Expect = 2e-40,   Method: Composition-based stats.
 Identities = 54/346 (15%), Positives = 105/346 (30%), Gaps = 23/346 (6%)

Query: 4   FDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
            DV IIG GP G ALA  LA   ++V  ++K          K     + P     F   G
Sbjct: 26  CDVLIIGSGPTGLALACDLARRGIKVRIIEKSAVPFNGSRGK----GIQPRTIEVFDNLG 81

Query: 63  ----------LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSL-I 111
                     L  P+    +        +            +   + +   +  ++    
Sbjct: 82  VAQPLLGVGQLYPPMKFHVSFLKIKWNMMKYQKQTADIPYPNVWLVPQWRTEQVLRDRLA 141

Query: 112 PASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQI 171
               +V  D+   +I ++ +   V     G  + + ARYLVGADG  S VR+ L  +   
Sbjct: 142 ELGTQVEWDTGALQIKQDAEGVSVRVACQGEPRIVHARYLVGADGGKSFVRKQLGVNFTG 201

Query: 172 RKYVAIQQWFAEKH--PVPFYSCIFDNSITNCY--SWSISKDGYFIFGGAYPMKDGQTRF 227
                 +    + H   +   +     +          +     F         +     
Sbjct: 202 STSQEGRMIVGDLHVEGLSRDAWHIWPTRKGGMIGLCPLPHSSLFQLMMRLDADEPAPEL 261

Query: 228 TTLK---EKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLE 284
           +        ++A   +          +V  P+         +  FL G+AA   + +  +
Sbjct: 262 SEHAIQTRWLAATGSRKIHLHSPTWLSVFRPNVRLAERYRVERVFLAGDAAHVHTPAGAQ 321

Query: 285 GISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSR 330
           G++  +     L   L    +    A      + R  +   +++  
Sbjct: 322 GLNTGVQDAWNLGWKLAAVLDGAPEALLDTYEEERRPVAAAVLELS 367


>UniRef50_Q5FR44 Putative oxidoreductase n=1 Tax=Gluconobacter oxydans
           RepID=Q5FR44_GLUOX
          Length = 419

 Score =  169 bits (428), Expect = 2e-40,   Method: Composition-based stats.
 Identities = 53/331 (16%), Positives = 94/331 (28%), Gaps = 29/331 (8%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
             DV +IG GPAGS  A  LA +   + L +K            G  L P         G
Sbjct: 10  DCDVLVIGGGPAGSTAATLLARQGYDVVLVEKDAHPRFHI----GESLLPCNLPLLRDLG 65

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSY---------ININRHAFDLWM-KSLIP 112
           +   V  +        + V         +   Y           + R  FD  + ++   
Sbjct: 66  VLDQVQAMG-VYKPGAEFVSEREDRRVPFPFRYAIGARDDHAYQVVRSQFDELLFRNAAR 124

Query: 113 ASVEVYHDSLCRKIWREDD-KWHVIFRAD-GWEQHITARYLVGADGANSMVRRHLYPD-- 168
              + +  +    +      +  V  + D G E+ +  R+++ A G    + R L     
Sbjct: 125 HGAQTHEQTRVLSVDFHAGQRATVKIKDDTGTERTLKPRFVLDASGREGFLSRTLRRRTA 184

Query: 169 HQIRKYVAIQQWFAEKHPVPFYS--CIFDNSITNCYSWSIS-KDGYFIFGGAYPMKDGQT 225
            +     AI   F             I  + +   + W I   DG    G        + 
Sbjct: 185 DRNNSTAAIFSHFRNVPRRDGDMGGYISIHLVDQGWFWMIPLPDGVMSVGFVGDKAAFKN 244

Query: 226 RFTTLKEKM-------SAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFI 278
               + +          A   +          +      ++      D  +LIG+A  F+
Sbjct: 245 HVGPVTDLFWEKVRESPAVAARMAHATALADLSTTGNYSYRADRAWGDGYYLIGDAYAFL 304

Query: 279 SASSLEGISYALDSTDILRSVLLKQPEKLNT 309
                 G+  A+ S      V     +    
Sbjct: 305 DPVFSSGVLLAMRSAYRGAEVAAAWLKSPER 335


>UniRef50_Q31RA2 Geranylgeranyl reductase n=13 Tax=cellular organisms
           RepID=Q31RA2_SYNE7
          Length = 457

 Score =  168 bits (426), Expect = 3e-40,   Method: Composition-based stats.
 Identities = 70/374 (18%), Positives = 126/374 (33%), Gaps = 38/374 (10%)

Query: 6   VAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTL 65
           VA++G GPAGS  A  L        L ++         KPCGG +       F      +
Sbjct: 47  VAVVGGGPAGSCAAETLVKAGIETYLIERKLDNA----KPCGGAIPLCMVSEFD-LPAEI 101

Query: 66  PVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLC-- 123
               + N ++ S    +V  +L    +   +   R   D +++           +     
Sbjct: 102 IDRRVRNMKMISPSNREVNINLDNADEYIGMT-RREVLDGFLRDRAAKLGTKLINGTLFR 160

Query: 124 RKIWREDDKWHVIFRAD-------GWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVA 176
            ++ + D   +V+  AD       G    +    ++GADGANS + + +         +A
Sbjct: 161 LELPKGDRDPYVLHYADHSNGSLEGIPSTLEVDVVIGADGANSRIAKAIDAGD-YNYAIA 219

Query: 177 IQQWFAEKHPVPFY------SCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQ--TRFT 228
            Q+          Y        +  +   + Y+W   K  +   G      + +   +  
Sbjct: 220 FQERIRLPEDKMHYYENLAEMYVGGDVSPDFYAWVFPKYDHVAVGTGTMHVNQRLIKKLQ 279

Query: 229 TLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISY 288
                 +A + + GK +K E      P   +        A L+G+AAG+++ SS EGI +
Sbjct: 280 AGIRARAANRLEGGKIIKVE--AHPIPEHPRPRRVV-GRAALVGDAAGYVTKSSGEGIYF 336

Query: 289 ALDSTDILRSVLLKQP--------EKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKW 340
           A  S  +    +++          E     Y R   K     +  +     L     R  
Sbjct: 337 AAKSGRMCAETIVETSNNGARIPTEADLKQYLRRWDKKYGTTYKVL---DLLQTVFYRSD 393

Query: 341 IMRSGVAHIPQLKD 354
             R     +   KD
Sbjct: 394 ATREAFVEMCDDKD 407


>UniRef50_A8ABI3 Geranylgeranyl reductase n=1 Tax=Ignicoccus hospitalis KIN4/I
           RepID=A8ABI3_IGNH4
          Length = 444

 Score =  168 bits (426), Expect = 3e-40,   Method: Composition-based stats.
 Identities = 60/351 (17%), Positives = 112/351 (31%), Gaps = 21/351 (5%)

Query: 3   HFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            +D  ++G G  G   A+ LA    +V+ ++ K +   E  +K CG  ++      F + 
Sbjct: 2   EYDAVVVGAGTTGLVAAKFLAEAGYKVLVVELKAE--EEVGTKVCGDAISK---EYFEKI 56

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLI-PASVEVYHD 120
            +  P +   +  I   K                  +NR  F  W+ ++   A  E    
Sbjct: 57  PIGNPPEEAVDGNIVGAKIYSPDEETVWTVPGEGYMLNRKKFGEWLYNMAKEAGAEFSFK 116

Query: 121 SLCRK-IWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHL-------YPDHQIR 172
           +     + +++    +  R DG  + + AR +V A G   +VRR L        P     
Sbjct: 117 TRALGPVVKDNKVVGLTVRKDGKVETVRARLVVDASGVAYVVRRALPKSWPVAEPLDPKD 176

Query: 173 KYVAIQQWFAEKHPVPF--YSCIFDN--SITNCYSWSISKDGYFIFGGAYPMKDGQTRFT 228
             VA ++      P+    Y  I+         Y W     G         ++ G     
Sbjct: 177 TAVAYREIRRITTPLEDDKYIRIYVGQQKAPGGYWWLFPYRGGARVNLGLGVQGGVGHKD 236

Query: 229 TLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISY 288
            +         +F           + P+R              G+AA  ++     GI  
Sbjct: 237 PMWYFHEYLAPRF-PGEVEHAGGGVVPTRRPLDTMVAHGFATAGDAAYQVNPIHGGGIGS 295

Query: 289 ALDSTDILRSVLLKQPEKLNT-AYWRATRKLRLKLFGKIVKSRCLTAPALR 338
            +    +L    +K  E+  T        K  +  +G    +  +    L+
Sbjct: 296 GMLGAYLLAKTAVKALEEEPTVENLWKYNKDFMDAYGAKQAALDVFRVFLQ 346


>UniRef50_A8M3W4 Geranylgeranyl reductase n=1 Tax=Salinispora arenicola CNS-205
           RepID=A8M3W4_SALAI
          Length = 382

 Score =  168 bits (425), Expect = 3e-40,   Method: Composition-based stats.
 Identities = 61/355 (17%), Positives = 117/355 (32%), Gaps = 20/355 (5%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           M  +D+A++G GPAG + A   A       + ++         K CGG L   +      
Sbjct: 1   MTVWDLAVVGAGPAGLSAAYVAARAGVDTVVLERA---VHPRYKTCGGGLIGTSLAVVAD 57

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASV-EVYH 119
             + +P    A+   F+          +         + R  FD  +++   A+   +  
Sbjct: 58  R-IEVPAHDRADRVTFTWSGRRAFTRRSAGGPLVT-MVRRDEFDDRLRAAAVAAGATLRQ 115

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQ 179
               R +  E D   +          +TAR ++GADG++ +  RH+   H+        +
Sbjct: 116 RVAVRSVEPEPDGVRLRLV---DGTTVTARSVIGADGSSGVTARHVGVRHRQVDLGLELE 172

Query: 180 WFAEKHPVPFY---SCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSA 236
                     +     +    +   Y+W   K+     G       G+     L+  +  
Sbjct: 173 LPVPPALQARWRGRVLVDWGPLPGSYAWVFPKNDLLTVGVIAARGAGERTRAYLRSFVDR 232

Query: 237 FQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDIL 296
                           L   R +     +    + G+AAG +   S EGISYAL S ++ 
Sbjct: 233 LG--LADVEPVHDSGHLTRCRQEGSPLRRGRVLVAGDAAGLLEPWSREGISYALRSGELA 290

Query: 297 RSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAHIPQ 351
            + +            +    +  +L   +   + L     R+  +  G+   P 
Sbjct: 291 GAAVAADDLG------QYEPAVVAELVPSMRAGQRLLHIFSRRPGVFHGLLATPP 339


>UniRef50_C0VR61 Geranylgeranyl reductase n=2 Tax=Corynebacterium glucuronolyticum
           RepID=C0VR61_9CORY
          Length = 385

 Score =  168 bits (425), Expect = 4e-40,   Method: Composition-based stats.
 Identities = 51/324 (15%), Positives = 95/324 (29%), Gaps = 23/324 (7%)

Query: 20  RKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVK 79
             L  K  V+ +D           K CG  L P A R     G+ LP            +
Sbjct: 24  IHLQDK-DVLLID----SAEFPRDKTCGDGLTPRAMRELSALGIDLPFRTRGLKLHGFGR 78

Query: 80  TVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLCRKIWREDDKWHVIFRA 139
           T ++              + R  FD  + +  PA        +      E+ +     R 
Sbjct: 79  TAEIPWEW-----GVGSAMRRQEFDALLYNRAPA---QKLTGVATSPVVENGRV---VRF 127

Query: 140 DGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEKHPVPFYSCIFDN-SI 198
              E  +  + ++ ADG  S     L      ++   I        P      I  +   
Sbjct: 128 QVGEHVVHPQVVLVADGVRSTFGTQLGRVWHKQQVYGIAARSYCTSPRSSEPWIHSHFGD 187

Query: 199 TNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAF----QFQFGKTVKSEKCTVLF 254
              Y W          G        +      K+ +  +    Q +FG    +   +   
Sbjct: 188 LPGYGWFFPLVDAANVGCGALSTAARPAKVNTKKLLRFYASSIQEEFGLGEPTSVTSAAL 247

Query: 255 PSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRA 314
           P           N  L+G++A  ++  + EGI YAL++  +  S++ +      +     
Sbjct: 248 PMGGSVSGVSGRNWALLGDSACCVNPLNGEGIDYALETARLAASLIDEDLRVWPSVLREH 307

Query: 315 TRKLR--LKLFGKIVKSRCLTAPA 336
             +     +   K++    +    
Sbjct: 308 YGETFTLARSLAKLLTYPRMLPTF 331


>UniRef50_Q9HLA3 FixC protein related n=2 Tax=Thermoplasma RepID=Q9HLA3_THEAC
          Length = 428

 Score =  168 bits (425), Expect = 4e-40,   Method: Composition-based stats.
 Identities = 71/356 (19%), Positives = 123/356 (34%), Gaps = 46/356 (12%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M  FDV +IG GPAGS+ A KLA     V+ +++    GT+  S   G +L  D     +
Sbjct: 1   MSEFDVIVIGAGPAGSSAAIKLAQGGMNVLLVERGDPPGTKNVS---GAVLWGDELSKVV 57

Query: 60  RDGLT-LPVDVIANPQIFSVKTVDVAASLTRNYQR-----SYININRHAFDLWMKSLIP- 112
            D     P++     +  +  T     +++ + Q      S   I R  FD W+      
Sbjct: 58  PDWERSAPIERYVTRKEVAFLTEKSKIAISYSSQELMEKKSGKIIVRGKFDQWLARKAKD 117

Query: 113 ASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIR 172
           A   +       K+  +  K  +    DG    IT+  ++ A+GAN  V  +     ++ 
Sbjct: 118 AGAMLVTGITVDKLVIDGGKV-IGVMQDGD--VITSDAVIVAEGANPRVLINSGLRPKLS 174

Query: 173 KY-VAIQQWFAEKHPVPFYSCIFDNSITNCY----------------SWSISKDGYFIFG 215
            + VA+      K P    +  F+      Y                 +  +       G
Sbjct: 175 DHDVALGIKETIKLPENVINERFNVDSKGGYASEFVLGFLDDGLLSGGFLYTNRDTISLG 234

Query: 216 GAYPMKDGQTR-FTTLKEKMSAFQFQF------GKTVKSEKCTVLFPSRW--QDFVCGKD 266
               +   +    T   + M  F+            +  E    L P            +
Sbjct: 235 IVTSLDRLRANGMTHSYDIMGKFEDHPFIKNLIKDGIPDEYAAHLVPEGGLASMPKLYGN 294

Query: 267 NAFLIGEAAGFI--SASSLEGISYALDSTDILRSVLLKQ----PEKLNTAYWRATR 316
              + G+AA F   +   L+GI+YA+ S  +    +L+      E+  + Y    R
Sbjct: 295 GYLVAGDAAMFTFSNGMVLQGINYAITSGMLAAETILENKGKISEETLSTYVSKLR 350


>UniRef50_A1KG38 Possible oxidoreductase n=11 Tax=Mycobacterium RepID=A1KG38_MYCBP
          Length = 408

 Score =  167 bits (424), Expect = 4e-40,   Method: Composition-based stats.
 Identities = 50/325 (15%), Positives = 96/325 (29%), Gaps = 25/325 (7%)

Query: 27  QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTVDVAAS 86
            V+ +D      T    KPCG  L P A     + GL   +      +   +        
Sbjct: 31  DVLVID----TATFPRDKPCGDGLTPRAVAELHQLGLGKWLADHIRHRGLRMSGFGGEVE 86

Query: 87  L---TRNYQRSYININRHAFDLWMKSLIPA-SVEVYHDSLCRKIWREDDKWHVIFRADGW 142
           +     ++      + R   D  ++ +       +   +    +  +  +  V       
Sbjct: 87  VDWPGPSFPSYGSAVARLELDDRIRKVAEDTGARMLLGAKAVAVHHDSSRRVVSLTLADG 146

Query: 143 EQHITARYLVGADGANSMVRRHLYPDHQIRK--YVAIQQWFAEKHPVPFYSCIF------ 194
              +  R L+ ADGA S + R L           VA++ + +  +    +          
Sbjct: 147 T-EVGCRQLIVADGARSPLGRKLGRRWHRETVYGVAVRGYLSTAYSDDPWLTSHLELRSP 205

Query: 195 DNSITNCYSWSIS-KDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKTV-----KSE 248
           D ++   Y W     +G    G        +     L+  +S +                
Sbjct: 206 DGAVLPGYGWIFPLGNGEVNIGVGALSTSRRPADLALRPLISYYTDLRRDEWGFTGQPRA 265

Query: 249 KCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKLN 308
             + L P           N  LIG+AA  ++  + EGI Y L++  +   +L      L 
Sbjct: 266 VSSALLPMGGAVSGVAGSNWMLIGDAAACVNPLNGEGIDYGLETGRLAAELLD--SRDLA 323

Query: 309 TAYWRATRKLRLKLFGKIVKSRCLT 333
             +         + F    +   L 
Sbjct: 324 RLWPSLLADRYGRGFSVARRLALLL 348


>UniRef50_Q2FLI3 Geranylgeranyl reductase n=1 Tax=Methanospirillum hungatei JF-1
           RepID=Q2FLI3_METHJ
          Length = 384

 Score =  167 bits (424), Expect = 4e-40,   Method: Composition-based stats.
 Identities = 61/338 (18%), Positives = 108/338 (31%), Gaps = 31/338 (9%)

Query: 1   ME-HFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSF 58
           M   +DVAI+G GP GS  AR  A   ++ + ++++      G+   C GLL+  A R  
Sbjct: 1   MNRTYDVAIVGGGPVGSTAARICAKSGLKTLLIEEQAH---FGYPVQCAGLLSDSAFREC 57

Query: 59  IRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVE-V 117
                ++   V          T    A  T         ++R A D  M      +   +
Sbjct: 58  EVSCSSVLNTVSGADVHAGEATCSFDAGRTM-----AYVVDRGALDHEMGKAAADAGADI 112

Query: 118 YHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAI 177
              ++   I R      +  +     + ++   L+ ADG  S + R +           +
Sbjct: 113 QLKTIASGISRTSG--ILHLKGVNGPEDVSYSMLIAADGPRSSISRMVGIPRAPVYLSGL 170

Query: 178 QQWFAEKHPVPFYSCIFDNSITNCYSWSIS-KDGYFIFGGAYPMKDGQTRFTTLKEKMSA 236
           Q       P P +  I+ N+    + W I         G              +KE+ S 
Sbjct: 171 QCDVHHALP-PDHVQIYPNASPEFFGWMIPLHPDQTRIGLCG--------IHHVKERFSE 221

Query: 237 FQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDIL 296
           F   F     +   +   P          D   + G+AA     +S  G+   + +    
Sbjct: 222 FIKPFQNKA-THFVSGTIPLGTLTRSY-DDRILIAGDAAAMAKPTSGGGVYTGIRAARHA 279

Query: 297 RSVLLKQPE------KLNTAYWRATRKLRLKLFGKIVK 328
             V ++  E      K   +Y  A +        +   
Sbjct: 280 AEVAIRCIEMDDFSPKAMASYEHAWKADFGHEILRGFH 317


>UniRef50_C6W802 Monooxygenase FAD-binding n=1 Tax=Actinosynnema mirum DSM 43827
           RepID=C6W802_ACTMD
          Length = 444

 Score =  167 bits (424), Expect = 5e-40,   Method: Composition-based stats.
 Identities = 54/379 (14%), Positives = 110/379 (29%), Gaps = 39/379 (10%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           ++  +IG   AG+A+   LA +   + +  +               + P       R G+
Sbjct: 2   YNAIVIGGRCAGAAVGTHLARRGLRVLVVDRS---RFPSDVLSTHFVWPHGASYLNRLGV 58

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQRS-------------------YININRHAFD 104
              V  +  P   SV  V+   +L  +                       Y ++ RH  D
Sbjct: 59  LDQVRAV-TPAHTSVTVVNDGIALRGSVPEELLRNQFRLLHDDDSGITQEYFSVRRHVLD 117

Query: 105 LWMKS-LIPASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRR 163
             +    + A VE        ++ R++D   V  R     +   A+ ++GADG NS V R
Sbjct: 118 KLLVDNAVRAGVEFREGYTVTELLRDEDGTVVGIRGRDGSEE-RAQVVIGADGRNSFVAR 176

Query: 164 HLYPDHQIRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDG 223
            L  +    +      +++    +P              + + + DG  +     P +  
Sbjct: 177 ALGLEKFDERPRCTFAYWSYFSGIPDAEAQIHRRGRLGMAMASTNDGRTMVLTWGPSEWA 236

Query: 224 QTRFTTLKEKMSAFQFQF--------GKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAA 275
                 ++                   +  + E+                    L+G+A 
Sbjct: 237 AQFRADVEGNFHRALGLISEQAAVTVAQARREERFYGTLDQAAFLRRLHGPGWLLVGDAE 296

Query: 276 GFISASSLEGISYALDSTDILRSVLLKQPEKLNTA------YWRATRKLRLKLFGKIVKS 329
            F    +  GI++AL   ++    + +              Y    R      +   V +
Sbjct: 297 SFKDQCTALGITHALRDAELAAEAVGRWLGGETDRDTAMAGYAAKRRSQTAAAYYDYVCT 356

Query: 330 RCLTAPALRKWIMRSGVAH 348
                P     +    +  
Sbjct: 357 LAEMKPLRHDELQLFAILR 375


>UniRef50_A4JL31 Monooxygenase, FAD-binding n=3 Tax=Burkholderia cepacia complex
           RepID=A4JL31_BURVG
          Length = 461

 Score =  167 bits (424), Expect = 5e-40,   Method: Composition-based stats.
 Identities = 65/367 (17%), Positives = 109/367 (29%), Gaps = 21/367 (5%)

Query: 5   DVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           D  IIG   AG+ LA  LA    +V+A+D  H    +  S      ++P          L
Sbjct: 3   DTLIIGARCAGATLAIHLARAGKRVLAIDANHLPSDQPLS---THWISPYGMALLDELEL 59

Query: 64  TLPVDVIANP-QIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPA-SVEVYHDS 121
              V   A P         DV   +            R   D  +     A   EV   +
Sbjct: 60  GDKVRRFAPPVPSMMYGNDDVTGRVEYPVGGRCSCPRRMDLDALLLEEARASGAEVRART 119

Query: 122 LCRKIWREDDKWH-VIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQ---IRKYVAI 177
               + R+ ++    +   DG  + I AR +VGADG +S     +  +            
Sbjct: 120 RLVGLLRDGERVTGAVVEHDGVREEIRARIVVGADGPHSTTAELVGAEEYHGYDCPRAMY 179

Query: 178 QQWFAEKHPVPFYSCIFDN----SITNCYSWSISKD-GYFIFGGAYPMKDGQTRFTTLKE 232
             ++                   +  +   +    +    + G A+P            E
Sbjct: 180 WAYWPRPDWFDTDPRYLGGAMNCTFGDDIVFVFPTNRDLLLIGVAFPKTQLPQWKGRALE 239

Query: 233 KMS------AFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGI 286
           K++                   K       R+           L+G+A  F+  S   GI
Sbjct: 240 KLTETLKGNRHTAPLITGEPVSKVLGALKLRFFFRQAAGPGWALVGDAGLFMDPSPGFGI 299

Query: 287 SYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGV 346
           + AL     L   +++  ++    YWR      + LF        L        I+   +
Sbjct: 300 TDALRDARALGQAIVEDDDRALECYWRQRDATSIDLFEYSRGRGALGHNNPLSRILFGKL 359

Query: 347 AHIPQLK 353
              P L+
Sbjct: 360 TADPVLQ 366


>UniRef50_B2SJD1 Hydroxylase n=12 Tax=Xanthomonas RepID=B2SJD1_XANOP
          Length = 461

 Score =  167 bits (424), Expect = 6e-40,   Method: Composition-based stats.
 Identities = 56/357 (15%), Positives = 106/357 (29%), Gaps = 30/357 (8%)

Query: 5   DVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           DV I+G GPAG   A  LA     + L +K Q          G  L P       R G+ 
Sbjct: 26  DVLIVGGGPAGCTAAIALAELGWSVTLLEKEQHPRFHI----GESLLPMNMPILERLGVL 81

Query: 65  LPVDVIANPQIFSVKTVDVAASLTRNYQ-------RSYININRHAFDLWMKSLIP-ASVE 116
             V  I   +  +    D     T  +             + R  FD  +      A V+
Sbjct: 82  ADVRAIGVLKRGADFPNDSGGYNTFRFSHALDAKADFAFQVPRAQFDQVLFQRARAAGVD 141

Query: 117 VYHDSLCRKIWREDDKWHVIFRA-DGWEQHITARYLVGADGANSMV--RRHLYPDHQIRK 173
                   ++  + ++  +  R  DG  Q    RYL+ A G ++ +  R  L   +   +
Sbjct: 142 AREQVSVEQVAFDGEQPLLQARTVDGGVQQFRPRYLLDASGRDTFLGTRLKLKRANAKHQ 201

Query: 174 YVAIQQWFAE--KHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLK 231
             A+   F    + P      I      + + W I      +  GA    +         
Sbjct: 202 SAALFSHFRGVTRRPGEDAGNISIYRHAHGWMWLIPLPEDIMSVGAVCYPEYMKTRKGDS 261

Query: 232 EKM--------SAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSL 283
           E               +     +           ++          ++G+A  F+     
Sbjct: 262 EAFLMRTLALNPELNARMLDAERVAPVHATGNYAYECTRMAGPRWLMLGDAYTFVDPMFS 321

Query: 284 EGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKW 340
            G+  A+   +   +++        +       KL+  L  ++ +        + ++
Sbjct: 322 SGVFLAMHGAERGAAMVDAALRAPQSEA-----KLQRALQRELTRGVDEFKWFIYRF 373


>UniRef50_Q8GHB4 Putative halogenase n=1 Tax=Streptomyces roseochromogenes subsp.
           oscitans RepID=Q8GHB4_9ACTO
          Length = 524

 Score =  167 bits (423), Expect = 7e-40,   Method: Composition-based stats.
 Identities = 55/361 (15%), Positives = 107/361 (29%), Gaps = 45/361 (12%)

Query: 2   EHFDVAIIGLGPAG------SALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQ 55
           + +DV +I            S ++  LA   + + + +  +          G  L     
Sbjct: 5   QEYDVIVI------GGGPGGSMVSSLLADGGKKVLVLEVAKFPRYHI----GESLLLGTV 54

Query: 56  RSFIRDGLTLPVDVIANPQIFSVKTVDVAASLTRN---------YQRSYININRHAFDLW 106
               + G+   ++     + + V+ V                         + R  FD  
Sbjct: 55  DLLDKIGVREKLEAGDYIKKYGVEWVWGEQREPWKVDFRNAVSVTHDYTYQVERGPFDKM 114

Query: 107 MKSLIPA-SVEVYHDSLCRKIWREDDKW-HVIFRAD--GWEQHITARYLVGADGANSMVR 162
           +        V+V           +D+    V +R    G     TAR+LV A G   +V 
Sbjct: 115 LLDNAREHGVDVREQHRVTNFSIDDNGRSTVNYRRTDTGETGTATARWLVDASGQGGLVT 174

Query: 163 RHLYPD--HQIRKYVAIQQWFAE--KHPVPFYSCIFDNSITNCYSWSIS-KDGYFIFGGA 217
           + L+        K +A+  ++    +        IF  +  + + W I  +D     G  
Sbjct: 175 KRLHTQEWDPYLKNMAVWSYWKGVKRSEGEDAGNIFLPTFDDGWWWCIPLRDDITSIGAV 234

Query: 218 YPMKDG--------QTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAF 269
              +          +  +    EK      +       +   V     +       D   
Sbjct: 235 VDRESLNALKSTRVRQYYLDSIEKTPELASRTENAELVDDMHVQRDWSYIYDRFCGDGYI 294

Query: 270 LIGEAAGFISASSLEGISYALDSTDILR---SVLLKQPEKLNTAYWRATRKLRLKLFGKI 326
            IG+AA FI      G+  A+ S  +     + +L +PE       +       K F ++
Sbjct: 295 AIGDAACFIDPLFSTGVHLAMLSGFLAATVVNTILDKPELDTARMLQFYEGAYRKEFARL 354

Query: 327 V 327
            
Sbjct: 355 R 355


>UniRef50_Q21HW5 Monooxygenase, FAD-binding n=1 Tax=Saccharophagus degradans 2-40
           RepID=Q21HW5_SACD2
          Length = 575

 Score =  166 bits (422), Expect = 7e-40,   Method: Composition-based stats.
 Identities = 68/401 (16%), Positives = 128/401 (31%), Gaps = 55/401 (13%)

Query: 5   DVAIIGLGPAGSALARKLAGKMQV--IALDKKHQCGTEGFSKPC-GGLLAPDAQRSFIRD 61
           DV ++G GP G +LA +L  +       +DK  + G +  S       +           
Sbjct: 8   DVLVVGAGPIGLSLAIQLKSQGFTQFRVIDKTDEPGEKLISSISRAIGVHARTLEVLEDV 67

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSY----------ININR----HAFDLWM 107
           G+T  +         +    +   +   +Y                + +          +
Sbjct: 68  GVTPSLLERGKIAHTASNYYNSKLTYRVDYPSGCDTSHVKYNWNFMVTQGNTIDVLHTHL 127

Query: 108 KSLIPASVEVYHDSLCRKIWREDDKWHVIFRAD--GWEQHITARYLVGADGANSMVRRHL 165
              +   VE   ++   +    D     I + D  G  + I A+YLVG DG +S VR+ L
Sbjct: 128 SKKLDHKVE--WNTSLVEFKETDAGITAIIKNDITGELETINAKYLVGCDGCHSAVRKGL 185

Query: 166 YPDHQIRKYVA--IQQWFAEKHPVPFYSCIFDNSITNCYSWSIS----KDGYFIFGGAYP 219
             D   + Y    +      +  +P     F   I N Y+ ++      +G F      P
Sbjct: 186 GIDFPGKVYPVKWVVCDLDIEWDIPHDDITFLG-IKNAYAIALPLAGGGEGRFRVTMGMP 244

Query: 220 MKDGQTRFTTL-----------KEKMSAFQFQFGKTVKSEKCTVLFPSRWQD-----FVC 263
           + + + +               KE+  AF  +   + K +         +Q         
Sbjct: 245 LTEEEKKDHYEHAQPIRGGRFGKEECVAFFKKLYPSAKVKSTPAEPQQWFQVHCRMATTL 304

Query: 264 GKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLL-----KQPEKLNTAYWRATRKL 318
            K N FL+G+AA   S    +G++  +     L   L+         KL   Y +     
Sbjct: 305 AKGNCFLVGDAAHVHSPVLGQGMNMGIQDAANLAWKLVAVCRGDSSPKLLDTYKQEREFS 364

Query: 319 ------RLKLFGKIVKSRCLTAPALRKWIMRSGVAHIPQLK 353
                  +    K+V +        R +++   +   P  +
Sbjct: 365 DTEIVNFVDKVTKLVITPSRFIQYARGFVLSRILKVTPGRR 405


>UniRef50_A8L4I1 Monooxygenase FAD-binding n=7 Tax=Actinomycetales
           RepID=A8L4I1_FRASN
          Length = 411

 Score =  166 bits (422), Expect = 8e-40,   Method: Composition-based stats.
 Identities = 55/338 (16%), Positives = 96/338 (28%), Gaps = 22/338 (6%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           +DV ++G   AGS LA  LA +   + +  +    T          +           GL
Sbjct: 2   YDVIVVGARCAGSPLAMLLARQGHRVLVVDRS---TFPSDTVSTHYMHQTGLARLRDWGL 58

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTR-NYQRSY----ININRHAFDLWMKSLI-PASVEV 117
              +     P +  +        L              +  R   D  +      A  EV
Sbjct: 59  LDRLVATGVPPMRHLTFSYTGLHLEGFADPIDGITEVYSPRRIILDKLLVDAAREAGAEV 118

Query: 118 YHDSLCRKIWREDDKWHVIFRADGW--EQHITARYLVGADGANSMVRRHLYPDHQIRKYV 175
                   +  +D +   I    G   EQ   A ++VGADG  S V   +  D       
Sbjct: 119 IEGFTVSDLLFDDGRVTGIRGRTGEGPEQEFRAAFVVGADGRTSTVADKVGADFYRVVPA 178

Query: 176 AIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTT----LK 231
           A   +++    + +            +    + DG  +     P               +
Sbjct: 179 AGFIYYSYFEGLDWTFQHRTGFGEQQFGAWPTHDGRHLVSIIRPRSAFSEFRADVEGSFQ 238

Query: 232 EKMSAFQFQFGKTVKSEKCTV--LFPSRWQD---FVCGKDNAFLIGEAAGFISASSLEGI 286
               A   + G+ +++    V    P R+ D            L+G+A       +  GI
Sbjct: 239 AIFDAVVPELGEDLRTRGRRVEEFRPMRYPDNYYRRSHGPGWALVGDAGYHKDPFTGWGI 298

Query: 287 SYALDSTDILRSVLLK--QPEKLNTAYWRATRKLRLKL 322
           + A      L   L      E+          K+R + 
Sbjct: 299 TDAFLQAQTLADRLHSGLAGERTLDDAAAEYVKIRDEE 336


>UniRef50_C6W874 Tryptophan halogenase n=2 Tax=Actinosynnema RepID=C6W874_ACTMD
          Length = 441

 Score =  166 bits (421), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 49/333 (14%), Positives = 97/333 (29%), Gaps = 31/333 (9%)

Query: 5   DVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           D  ++G GPAG+  A  LA + + + + ++ +          G  + P       R GL 
Sbjct: 3   DAIVMGGGPAGAVCASVLARQGRSVLVLERQEFPRFHI----GESMLPYMVGLLERHGLL 58

Query: 65  LPVDVIANPQIFSVKTVD-------VAASLTRNYQRSY-------ININRHAFDLW-MKS 109
             V           + +D        A     ++ ++          + R  FD   +  
Sbjct: 59  DAVREQGYVVKRGGEFIDPTGTKFFRAGVFRADFAKTGDGRHHETFQVERSHFDRVNLDQ 118

Query: 110 LIPASVEVYHDSLCRKIWREDDKW-HVIFRADGWEQHITARYLVGADGANSMVRRHLYPD 168
              A   V   +    +  E  +   V +R  G E+   ARY+V A G   +V       
Sbjct: 119 ARAAGATVREGAQVVGLLEEGGRVVGVRYREGGVEREERARYVVDATGRAGVVANRFGLR 178

Query: 169 HQIRKYVAIQQWFAEKHPVPFYSCIFDNSIT-----NCYSWSISKD-GYFIFGGAYPMKD 222
             I     +  +         ++   +  I      + + W+I         G       
Sbjct: 179 RMIEDLRMVAVFHHRDGLDEAHNPGHEGDIQVGSHADGWIWAIPLSADRISVGTVMHRDR 238

Query: 223 GQTR-----FTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGF 277
            + R     F    E++     +   T  +    V     +           ++G+A  F
Sbjct: 239 LRGRTPAEAFAEHVERVPRINQRLTGTTATSDFWVETDYSYHSDQVTGPGWVMVGDAGCF 298

Query: 278 ISASSLEGISYALDSTDILRSVLLKQPEKLNTA 310
                  G+   + +       L +  +     
Sbjct: 299 GDPMFSGGVLVGMATGAEAAEALGRALDSPADE 331


>UniRef50_D1C5T7 Monooxygenase FAD-binding protein n=2 Tax=Thermomicrobia (class)
           RepID=D1C5T7_SPHTD
          Length = 415

 Score =  166 bits (421), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 65/340 (19%), Positives = 112/340 (32%), Gaps = 28/340 (8%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           +D  I+G   AGS  A  LA +   I L  +        S     L   D+  +F R G+
Sbjct: 2   YDAIIVGARIAGSTTALLLAQRGYSILLLDRD---RFPSSTLSTHLFFTDSLSAFERIGV 58

Query: 64  TLPVDVIANPQIFSVKTVDVAASL-TRNYQRSYININRHAFDLWMKSLIPAS--VEVYHD 120
              V  I  P++  ++   V A     + +   + I R   D  +     A   +E++  
Sbjct: 59  LDRVLAIDAPRLKRLRFPYVDAPFAEVDGRDFALCIRREPLDAILVEAAGAHPEIELHTG 118

Query: 121 SLCRKIWREDDKW-HVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQ 179
           +    + RE ++   V ++  G E    AR+++GADG +S+V R +              
Sbjct: 119 ARVTGLLREGERVIGVRYQEAGQEHEARARFVIGADGRHSLVAREVGATAYEDFPPMFAW 178

Query: 180 WFAEKHPVPFYSCIFDNSITNCY---------SWSISKDGYFIFGG---------AYPMK 221
           ++     VP        ++   Y         S+    D      G         A+   
Sbjct: 179 YYGYFRGVPLDDPPSAFAVRGTYPEIGAEYAASFIFPCDDGLTLVGFGVQASAFDAFRRN 238

Query: 222 DGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISAS 281
             +  F  L     A   + G +                 V       L+G+A       
Sbjct: 239 HREHFFGGLARIPEAM-ERIGDSQLEGPIVGTGDLPNFLRVPVGPGWALVGDAGCHKDPH 297

Query: 282 SLEGISYALDSTDILRSVLLK--QPEKLNTAYWRATRKLR 319
           S++G+  A+ S  +L   L +  Q E             R
Sbjct: 298 SVQGMGDAVRSAQLLVESLDRWWQGEIDEQTALAEYHARR 337


>UniRef50_Q0SF87 Possible dehydrogenase n=23 Tax=Actinomycetales RepID=Q0SF87_RHOSR
          Length = 420

 Score =  166 bits (421), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 51/330 (15%), Positives = 95/330 (28%), Gaps = 25/330 (7%)

Query: 27  QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTVDVAAS 86
            V+              K CG  L P A       GL   V      +   +        
Sbjct: 41  DVVL----ADAAVFPRDKTCGDGLTPRAVAELDHLGLGDWVRSKGTNRGLRLSGFGQELE 96

Query: 87  LT---RNYQRSYININRHAFDLWMKS-LIPASVEVYHDSLCRKIWREDDKWH-VIFRADG 141
           L    R++      + R   D  +++  + A   +   +    + R+ D+   V  +   
Sbjct: 97  LEWPGRSFPAVGSAVARTELDDRIRATAVDAGAVMVQGAKAIGVERDGDRVTAVALKTSD 156

Query: 142 WEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEKHPVPFYSCIFD------ 195
               I  R L+ ADG  S + + L  +        +               I        
Sbjct: 157 GAHTIGCRTLIVADGVRSTLGKQLGREWHRDTAYGVAARAYIATDRSADPWITSHLELRD 216

Query: 196 --NSITNCYSWSISKD-GYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEK--- 249
              ++ + Y W      G    G        +     L+  +  +  Q     K +    
Sbjct: 217 GAGTLQSGYGWVFPLGTGEVNIGVGTLATAKRPAPGALRPLLDLYTAQRRDEWKWDGELR 276

Query: 250 --CTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKL 307
              + L P           N  +IG+AA  ++  + EGI Y L+   ++  +L    + L
Sbjct: 277 AVASALLPMGGAVSHIAGRNWAIIGDAAACVNPLNGEGIDYGLEGGRLVAEILD--SDDL 334

Query: 308 NTAYWRATRKLRLKLFGKIVKSRCLTAPAL 337
              +    R+   + F    +   L     
Sbjct: 335 TELWPAILRERYGRAFSVARRLAGLLTVPR 364


>UniRef50_UPI0001745691 hypothetical protein VspiD_29115 n=1 Tax=Verrucomicrobium spinosum
           DSM 4136 RepID=UPI0001745691
          Length = 676

 Score =  166 bits (420), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 58/360 (16%), Positives = 116/360 (32%), Gaps = 27/360 (7%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
            +DV I G GP G  LA  LA + + + + +K +             + P +       G
Sbjct: 277 EYDVVIAGAGPVGLLLANLLARQGRSVRIFEKSE---GHVRPSLAIGITPPSLEILRTLG 333

Query: 63  LTLPV-------DVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPA-- 113
           L + +       D +       +  V   + L   Y+   ++I +H     +   +    
Sbjct: 334 LDVELIQQGVFIDRVMVHGQTGLLGVCDFSKLEGAYRFV-LSIPQHVVMKVLHQNLLKYP 392

Query: 114 SVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRK 173
              + + +  + + ++  +  V   +   +  +T R++V  DG+   +R  L+       
Sbjct: 393 GASISYGTEVKALTQDASQVTVTV-SGAQDDVVTCRHMVACDGSRGRIREMLHIRSHGGS 451

Query: 174 YVA--IQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLK 231
           Y    I     +   +   + +F  +     S+ +  +            +         
Sbjct: 452 YGCHFIMADIPDHSCLDREAHLFFTADGAVESFPLPGNMRRWVV----QTEAAVTDADAT 507

Query: 232 EKMSAFQFQFGKTVKSEKCTVLF---PSRWQDFVCGKDNAFLIGEAAGFISASSLEGISY 288
             M   Q + G  V     T      P   Q    G    FL G+AA  +S    +G++ 
Sbjct: 508 ALMEIVQQRTGICVSPSGVTATSSFSPRWMQSETYGDGRVFLCGDAAHVMSPIGGQGMNT 567

Query: 289 ALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAH 348
                ++L   LL   +    +  RA        + +I       A     W M+ G   
Sbjct: 568 GFADAELLALTLLSMQDDPQPSTARAWSSA----YDRIRSKASRIATRRAAWGMKLGTMR 623


>UniRef50_D2PLJ7 Monooxygenase FAD-binding protein n=10 Tax=Actinomycetales
           RepID=D2PLJ7_9ACTO
          Length = 487

 Score =  166 bits (420), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 52/363 (14%), Positives = 106/363 (29%), Gaps = 32/363 (8%)

Query: 5   DVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           DV + G GP G  LA +L    ++V+ L+K+ +      S      L   +     + G+
Sbjct: 3   DVIVAGGGPTGMMLAGELRLQGVRVVVLEKEREPSPVVRSL----GLHTRSVEVMDQRGV 58

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQRSY---ININRHAFDLWMKS-LIPASVEVYH 119
                              +  +       ++   + + +   D  +    +    EV  
Sbjct: 59  LERFLAHGRQYPVGGFFAGIPKASPDGLDTAHPYTLGLPQTITDRLLTEWAVELGTEVRR 118

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQ-----IRKY 174
                 + ++D+              + ARYLVG DG  S VR+ L          +   
Sbjct: 119 GCAVAGLVQDDESVTATL---ADGTQLRARYLVGCDGGRSTVRKLLGVGFPGEPSTVETL 175

Query: 175 VAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFG----GAYPMKDGQTRFTTL 230
           +   Q  A    +         +    +     KDG +       G    +     F   
Sbjct: 176 LGEMQLTASAETLAEVMAEVRKTQLR-FGAMPLKDGLYRVVVPADGVADERAVPPTFEEF 234

Query: 231 KEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYAL 290
           K ++ A              +    +             L G+AA     +  +G++  +
Sbjct: 235 KRQLRAVGGTDFGVHSPRWLSRFGNATRLAERYRTGRVLLAGDAAHVHPPAGGQGLNLGV 294

Query: 291 DST-----DILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAP-----ALRKW 340
                    +   +    P+ L  +Y    R +   +         L +      A+R+ 
Sbjct: 295 QDAFNLGWKLAAEINGWAPDGLLDSYESERRPVAADVLDNTRAQMELMSTEPGPQAVRRL 354

Query: 341 IMR 343
           + +
Sbjct: 355 VAK 357


>UniRef50_C5C803 2-polyprenyl-6-methoxyphenol hydroxylase-like oxidoreductase n=1
           Tax=Micrococcus luteus NCTC 2665 RepID=C5C803_MICLC
          Length = 405

 Score =  165 bits (419), Expect = 2e-39,   Method: Composition-based stats.
 Identities = 57/340 (16%), Positives = 111/340 (32%), Gaps = 31/340 (9%)

Query: 5   DVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG- 62
           D  ++G GPAG      LA +  +V  L+K      +      G  + P   R   R G 
Sbjct: 14  DCVVVGAGPAGMMAGLLLARRGVRVTVLEKHADFFRDFR----GDTIHPSTMRVMDRLGI 69

Query: 63  ----LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYIN--INRHAFDLWMKSLIPA--S 114
               L +P   ++   + +     V A  +R  +       + +  F  ++     A  S
Sbjct: 70  IDRFLAIPHRRMSTVSVAAPDGESVFADFSRLSEPYNYVAFMPQWDFLDFIAEEARAYPS 129

Query: 115 VEVYHDSLCRKIWREDDKWH-VIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRK 173
            E+  ++   ++  + D+   V ++    E+ ++AR ++GADG +S VR   +       
Sbjct: 130 FELIREAQVTELLVDGDRARGVRYKTPEGERTLSARLVIGADGRHSTVRARAWLPPTESD 189

Query: 174 YVAIQQWFAEKHPVPFYSCIF-----------DNSITNCYSWSISKDGYFIFGGAYPMKD 222
                 WF                        D       ++ I K  Y +       + 
Sbjct: 190 APMDVLWFRISRQPDDQVPFVSTGKGFTIVSVDRGSYWQIAYCIPKGDYDVL----RSQS 245

Query: 223 GQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQD-FVCGKDNAFLIGEAAGFISAS 281
                  L E +     +F   + S     L            +     IG+AA  +S +
Sbjct: 246 TDVVAERLHEALPVLAERFRGEITSWDDLKLLAVSVNRLRRWHRPGLLCIGDAAHAMSPA 305

Query: 282 SLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLK 321
              GI+ A+        +L     +  +   +    ++ +
Sbjct: 306 GGVGINLAIQDAVAAARMLAPTLARGGSPSEQLLAHVQRR 345


>UniRef50_O29239 Bacteriochlorophyll synthase, 43 kDa subunit (ChlP-2) n=1
           Tax=Archaeoglobus fulgidus RepID=O29239_ARCFU
          Length = 364

 Score =  165 bits (419), Expect = 2e-39,   Method: Composition-based stats.
 Identities = 57/334 (17%), Positives = 106/334 (31%), Gaps = 27/334 (8%)

Query: 5   DVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           D A++G GPAGS  A  L     V   ++    G   F   C GL++    +        
Sbjct: 2   DAAVVGGGPAGSLAAILLGKSYDVALFEEHQSAG---FPVQCAGLVSDKCYKKLKEH--C 56

Query: 65  LPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLCR 124
                I N    +         +        + + R   D  +        +V+     R
Sbjct: 57  KAEKAIENHIKGAFFFSPSGKIVLEGRGE-AVVVERKILDRLLFERAAERAKVFVKEKAR 115

Query: 125 KIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEK 184
                 + + +I       + ++A  ++GADG NS VR H      +  + A+Q     +
Sbjct: 116 L-----NGFRIIT----PSREVSAEKIIGADGVNSTVREHFGFPT-MGFFTAVQVEAKFE 165

Query: 185 HPVPFYSCIFDNS--ITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFG 242
                   ++       + ++++I        G        +     +K   S      G
Sbjct: 166 PLDENCVELYFGGNWSDSFFAYAIPLGDTARIGVVSRSSPLRYLENLMKRHPSVSGRVEG 225

Query: 243 KTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLK 302
             V+     +      +     K +  LIG+AAG +   +  G+ Y L    I    L +
Sbjct: 226 SAVELNAGAIP----DRLVKFSKRDVALIGDAAGMVKPYTGGGLYYHL----IAAEKLAE 277

Query: 303 QPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPA 336
                   Y ++  K   + +      R L +  
Sbjct: 278 SFPD-LKGYEKSYLKEMGREYRFGYAVRKLYSLP 310


>UniRef50_D2XDX8 AzicO4 n=2 Tax=Kibdelosporangium sp. MJ126-NF4 RepID=D2XDX8_9PSEU
          Length = 503

 Score =  165 bits (419), Expect = 2e-39,   Method: Composition-based stats.
 Identities = 54/346 (15%), Positives = 103/346 (29%), Gaps = 21/346 (6%)

Query: 6   VAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           V ++G GP+G  LA +L      VI L++  +   E      G  L       F + GL 
Sbjct: 11  VIVVGAGPSGLMLAAELRLGGADVIVLERLAERTGESR----GLGLFIRTMEVFDQRGLL 66

Query: 65  LPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKS-LIPASVEVYHDSLC 123
                     +     V +  S+  N   +   + +   +  ++        ++      
Sbjct: 67  PRFGDPEQSSLGHFGGVPLDFSVLDNPHLANRTVPQSQTETVLEEWAAELGADIRRGHTV 126

Query: 124 RKIWREDDKWHVIFR-ADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFA 182
           R I  + D   V    ADG  + +  +YLVG DG  S+VR+    D          + F 
Sbjct: 127 RAIRPDADGVDVEVADADGTVRTLRCQYLVGCDGGRSVVRKQCGFDFP--GVAGTMEMFQ 184

Query: 183 EK-HPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTT---LKEKMSAFQ 238
                +          +          +            +     T      E ++A++
Sbjct: 185 VDLKGIEMKPREIGEKVAGGMVMGGPLEDGVFRITICERDNLPKERTEPVTFAETVAAWK 244

Query: 239 FQFGKTVK---SEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDST-- 293
              G+ +             S        +    L G+AA     +  +G++ ++  +  
Sbjct: 245 RLTGEDISAATPVWIGAFTDSTRLITEYRRGRVLLAGDAAHIHLPAGGQGMNTSIQDSVN 304

Query: 294 ---DILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPA 336
               +   V    P+ L   Y      +  +L         L    
Sbjct: 305 LGWKLAAVVRGTSPDSLLDTYHTERHPVGERLTMNTRAQALLFLRG 350


>UniRef50_A1T3S9 Geranylgeranyl reductase n=10 Tax=Actinomycetales
           RepID=A1T3S9_MYCVP
          Length = 418

 Score =  165 bits (418), Expect = 2e-39,   Method: Composition-based stats.
 Identities = 56/341 (16%), Positives = 96/341 (28%), Gaps = 30/341 (8%)

Query: 27  QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTVDVAAS 86
            V+ +D           K CG  L P A     R GL   +D     +   +        
Sbjct: 41  DVLVID----SAQFPRDKACGDGLTPRAIAELRRLGLQSWLDGRIAHRGLRMSGFGADVE 96

Query: 87  LTR---NYQRSYININRHAFDLWMKS-LIPASVEVYHDSLCRKIWREDDKWHVIFRADGW 142
           +     ++      + R   D  ++   +    ++        + R      V       
Sbjct: 97  VAWPGPSFPSISSAVPRTELDERIRLVAVDDGAKMKLGVKAVSVERGSGG-RVTGVVLDT 155

Query: 143 EQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEKHPVPFYSCIFD------- 195
            + +  R L+ ADGA S + R L  +        +        P      I         
Sbjct: 156 GEVVRCRDLIVADGARSTLGRALGREWHKETVYGVAIRGYIATPRSDEPWITSHLELRSP 215

Query: 196 -NSITNCYSWSIS-KDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKTV-----KSE 248
              +   Y W     +G    G        +     L+  M+ +                
Sbjct: 216 AGEVLPGYGWIFPLGNGEVNIGVGALATAKRPADAALRPLMNYYAGLRRDEWGFSGDPRA 275

Query: 249 KCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKLN 308
             + L P           N  LIG+AA  ++  + EGI Y L++  +  S+L       +
Sbjct: 276 GLSALLPMGGAVSGVAGPNWMLIGDAAACVNPLNGEGIDYGLETGRLAASLLGSGS--YS 333

Query: 309 TAYWRATRKLRLKLFGKIVKSRCL-----TAPALRKWIMRS 344
            A+         + F    +   L       PA     MRS
Sbjct: 334 AAWPALLHGHYARGFSIARRLALLLTFPRFLPAAGPLAMRS 374


>UniRef50_D2RGA8 Dehydrogenase (Flavoprotein)-like protein n=1 Tax=Archaeoglobus
           profundus DSM 5631 RepID=D2RGA8_ARCPR
          Length = 357

 Score =  165 bits (418), Expect = 2e-39,   Method: Composition-based stats.
 Identities = 63/332 (18%), Positives = 111/332 (33%), Gaps = 30/332 (9%)

Query: 6   VAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTL 65
           + I+G GPAGS  A  L     V  +++    G   F   C GL++    R   +     
Sbjct: 2   ILIVGGGPAGSLSAIAL-KNYDVTVVEEHSSAG---FPVQCAGLISERCYRELKKF---- 53

Query: 66  PVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLCRK 125
             D   N    +V       S+    +   + + R   D  + +       V   +    
Sbjct: 54  -SDCKVNDIRGAVFFSPN-NSVELEGKVGAVVVERKLLDRDLLAKASEYANVMIKTKFLG 111

Query: 126 IWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEKH 185
           + +       + R+ G +  +   Y++GADG  S V            Y A+Q     + 
Sbjct: 112 VEKG----KAVLRSMGKKIELDYDYIIGADGVYSTVSNVFNFKKP-EVYSALQITCRFEC 166

Query: 186 PVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKTV 245
                  I+    ++ + ++I  D +   G        Q     ++  +     +   +V
Sbjct: 167 ISDDLVEIYFG-FSDYFCYAIPFDEFAKIGVI----SSQNPMPVMRRLLRWLGKRVKGSV 221

Query: 246 KSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLK--Q 303
             E      P    D    KD   LIG++AG +   +  G+ Y L         L     
Sbjct: 222 -LELNAGAIPIGLVD--FVKDRVMLIGDSAGMVKPYTGGGLYYILK----AVEKLKHFPN 274

Query: 304 PEKLNTAYWRATRKLRLKLFGKIVKSRCLTAP 335
            +K+   Y +  R +  K+  KI K      P
Sbjct: 275 LKKVQKEYVKDLR-IEYKVGTKIAKLYRTLEP 305


>UniRef50_Q11R94 Flavoprotein/dehydrogenase n=1 Tax=Cytophaga hutchinsonii ATCC
           33406 RepID=Q11R94_CYTH3
          Length = 413

 Score =  164 bits (417), Expect = 3e-39,   Method: Composition-based stats.
 Identities = 58/346 (16%), Positives = 105/346 (30%), Gaps = 32/346 (9%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           E  DV +IG GPAG+  A  +     +V  ++K+            G  L P        
Sbjct: 4   EKVDVLVIGAGPAGTVAASLVNKSGFKVKIVEKQK----FPRF-VIGESLLPRCMEHLDE 58

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSY-------ININRHAFDLWMK-SLIP 112
            G    V      Q F  K V        N+   +         + R  FD  +      
Sbjct: 59  AGFLDAVKAQGFQQKFGAKFVRGKEIADFNFSDQFSNGWNWTWQVPRGNFDKTLADEAAR 118

Query: 113 ASVEVYHDSLCRKIWRED-DKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQI 171
             V+V ++     I     D    I   +G ++ I AR+++ A G   ++ R    D   
Sbjct: 119 QGVDVEYEVGVTDIKFFGTDSVTTIEDINGNKREIEARFIIDASGYGRVIPRMFGLDKPS 178

Query: 172 --RKYVAIQQWFAEKHPVPFYSCIFDNSI------TNCYSWSIS-KDGYFIFGGAYPMKD 222
                  +     +    P  + +  N I         + W I   +G    G       
Sbjct: 179 GFESRRTLFTHIKDVK-RPVAAEMEGNRITAVVHKPKVWIWVIPFSNGNTSVGFVGEPSY 237

Query: 223 GQTRFTTLKEKMSAF-------QFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAA 275
                 T +E+M A          +F       +   +            D   L G A 
Sbjct: 238 FDEYTGTPEERMRAMIANEGHIAERFKSEEFLFEPRTIEGYAISASKLYGDGFVLTGNAT 297

Query: 276 GFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLK 321
            F+      G ++A++S      + ++  +     + +   +  ++
Sbjct: 298 EFLDPIFSSGATFAMESGSKGGKLAVQFLKGEEVNWEKDFVEHMMQ 343


>UniRef50_A6G4M1 Putative halogenase n=1 Tax=Plesiocystis pacifica SIR-1
           RepID=A6G4M1_9DELT
          Length = 427

 Score =  164 bits (417), Expect = 4e-39,   Method: Composition-based stats.
 Identities = 52/371 (14%), Positives = 113/371 (30%), Gaps = 48/371 (12%)

Query: 7   AIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTL 65
            IIG GPAG++ A +LA     V+  +K             G  L P   R     G++ 
Sbjct: 2   VIIGGGPAGTSAATQLAKKGYDVVLFEKAKHPREH-----VGESLIPHFWRYTDELGVSE 56

Query: 66  PVDVIANPQIFSVKTVDVAASLTRNYQRSYI-----NINRHAFDLWMKSLIPA-SVEVYH 119
            +      +      V        ++          ++ R  FD  +         + + 
Sbjct: 57  KILAEGFQEKTGGTVVWNGRIQQVSFSDFAYDRRALHVERARFDHILFQHCQENGAKTFE 116

Query: 120 DSLCRKI---WREDDKWHVIFRA--DGWEQHITARYLVGADGANSMVRRHLYP--DHQIR 172
             + + +        K  V++R      +  I   ++V A G  S++ R L      +  
Sbjct: 117 RVMVKSVRFAEEAGGKQTVVWRDIDAATDGEIECEFVVDASGQASVLGRQLDIWEIDEDF 176

Query: 173 KYVAIQQWFAEKH------------------PVPFYSCIFDNSITNCYSWSISKDGYFIF 214
           ++V++  +F                      P  F + + D      + W I+       
Sbjct: 177 RFVSLWGYFKGAKYVALDGKAHPFEKSREIKPTTFVTALKDGDGAWSWLWHITMRENTSV 236

Query: 215 GGAYPMKDGQTRFTTLKEKMSAFQF----------QFGKTVKSEKCTVLFPSRWQDFVCG 264
           G     ++        +   + ++                    + + +    ++     
Sbjct: 237 GLVISREELARAKANYESLEAYYRETCSTTPIINQLLEDATYEGEFSAIRDFSYRVKQAA 296

Query: 265 KDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFG 324
                +IG+AA FI     +GI  A  + ++    + +  ++      R       +L  
Sbjct: 297 GPGYLMIGDAATFIDPVFSQGIVLAFYTANLASWAIDRAMKRPEDT-ERTMAMYSHQLLM 355

Query: 325 KIVKSRCLTAP 335
           +   +R +  P
Sbjct: 356 RADMARSMALP 366


>UniRef50_UPI000178A157 monooxygenase FAD-binding protein n=1 Tax=Geobacillus sp. Y412MC10
           RepID=UPI000178A157
          Length = 520

 Score =  164 bits (417), Expect = 4e-39,   Method: Composition-based stats.
 Identities = 54/345 (15%), Positives = 110/345 (31%), Gaps = 27/345 (7%)

Query: 5   DVAIIGLGPAGSALARKLAGK-MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG- 62
           DV I+G GP G  LA  LA + +    +++         +K     + P +         
Sbjct: 9   DVLIVGAGPTGLTLACDLARRNVDHRIIERSALYNAASRAK----AIQPRSLEVVDDLEA 64

Query: 63  ---------LTLPVDVI---ANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSL 110
                    + LPV               TV  +A L   Y+     I ++  +  ++  
Sbjct: 65  VHYIMDTGVVDLPVRYYTADGRSVDKPAITVAASAELETPYRDPVW-IAQYDVEKALRGR 123

Query: 111 -IPASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDH 169
                 +V        + ++ D   V       E+ I A Y+VGADG  S +R+ ++   
Sbjct: 124 YAALGGQVELGVEAVGLEQDLDGVTVTMNTPQGEEQIRACYVVGADGGKSNIRKFIHLPL 183

Query: 170 QIRKYVAIQQWFAEKHPVP-FYSCIFDNSITNCYSWS--ISKDGYFIFGGAYPMKDGQTR 226
             + +   + +  +          I   + +        + K   +      P    +  
Sbjct: 184 VGKTHDQERWYLGDVRLEGLDRDHIHIWTSSEGMVGVTPLPKSDIWQLQATIPADIEEPE 243

Query: 227 FTTLKEKMSAFQFQFGKTVKS----EKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASS 282
             +L+   + F  + G  +         ++   +            FL G+AA   S + 
Sbjct: 244 QPSLEAYQAMFDRRAGAGLVRITNASWLSIYRVNVRMVECYRNGRVFLAGDAAHVHSPAG 303

Query: 283 LEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIV 327
            +G++  +     L   L       +TA      + R  +   ++
Sbjct: 304 GQGMNTGMQDAYNLGWKLATVIHGADTALLDTYDEERRPVAQAVL 348


>UniRef50_B8GUG5 Geranylgeranyl reductase n=5 Tax=Gammaproteobacteria
           RepID=B8GUG5_THISH
          Length = 363

 Score =  164 bits (417), Expect = 4e-39,   Method: Composition-based stats.
 Identities = 54/348 (15%), Positives = 108/348 (31%), Gaps = 17/348 (4%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           +   DV ++GLGP G++ AR  A   + V+A+++    G       C   +         
Sbjct: 8   IRSVDVLVVGLGPGGASAARTAAEAGLSVLAVERNKVLGE---PVQCAEFIPT------- 57

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPA-SVEVY 118
             G     + +   +I  +K++ + +      +   + INR  FD  +         E++
Sbjct: 58  PMGGYAKAEKVLLQRITGMKSI-LPSGTVHESEFPGLMINRAEFDRAIAREAERLGAELW 116

Query: 119 HDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQ 178
             S    +  + D      R +  E  +  + L+ ADG +S V   L  +  +      Q
Sbjct: 117 TRSPLVAL--DADARIATVRREDAEVKLRYKVLIAADGPHSPVAAQLGLE-PLVVVQTRQ 173

Query: 179 QWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAF- 237
                  P         +     Y+W   K      G     +        L        
Sbjct: 174 YTVPLLKPYADTDIWLSDEYPGGYAWLFPKGELANLGLGADRRWEDNLKEPLDRLHRQLV 233

Query: 238 QFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILR 297
           +          +     P           +   +G+AAG     +  GI+  + S ++  
Sbjct: 234 EAGLLGEEILYRTGGAIPVGGLREHLVVGDVLFVGDAAGLTHPITGAGIAAGVVSGELAG 293

Query: 298 SVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSG 345
                  E    A+      +R +    + ++        + W  R+ 
Sbjct: 294 KAAAAWLEGDEDAFEDYEEDVRDQFETAVSRAVERRHELAQHWRTRAA 341


>UniRef50_B8ES76 Monooxygenase FAD-binding n=1 Tax=Methylocella silvestris BL2
           RepID=B8ES76_METSB
          Length = 392

 Score =  164 bits (416), Expect = 4e-39,   Method: Composition-based stats.
 Identities = 64/376 (17%), Positives = 108/376 (28%), Gaps = 33/376 (8%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
            +D  +IG GPAG + A  LAG  + +A+ ++         K CG  ++        R G
Sbjct: 2   SYDAIVIGAGPAGCSAALALAGMGRRVAIVEQS---RFPRKKVCGEYMSAVNLDLLDRLG 58

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRS-----YININRHAFDLWMKSLI-PASVE 116
               V   A P +  V       ++     R+        + R   D  +      A   
Sbjct: 59  AGASVRARAGPSVRRVALFASGPAVEAGMPRAPGDAFGCALGRDVLDSVLLQAATDAGAA 118

Query: 117 VYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADG--ANSMVRRHLYPDHQIRKY 174
           V+       +        V   + G  + +TA  ++ A G  A   +   L   ++ + +
Sbjct: 119 VFQPWRAVDVCAGGAAAAVRIESAGESRVLTADAVIAAHGSWARGPLASQLERKNRRQDF 178

Query: 175 VAIQQWFAEKHPVPFYSCIFDNSITNCYSWSI-------------SKDGYFIFGGAYPMK 221
              +  F           +        Y   +              +D        Y   
Sbjct: 179 FGFKAHFRGASLARDLMPLL--VFPGGYGGMVWADQGRLSLSCCLRRDALARVRDLYRAP 236

Query: 222 DGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISAS 281
             Q  F  ++    A +   G            P R     C   + F +G  AG     
Sbjct: 237 AAQAVFAHIRASCPAARIALGGAALDGAWLAAGPIRPGVRACYAADIFRVGNIAGECHPI 296

Query: 282 SLEGISYALDSTDILRSVLLKQP-------EKLNTAYWRATRKLRLKLFGKIVKSRCLTA 334
             EGI+ AL S  +L   L +               Y  A R+              L  
Sbjct: 297 IAEGIAMALQSGWLLACALARHDVWDARSRAAAGRDYSEAWRRQFSTRIAAGAVLARLAI 356

Query: 335 PALRKWIMRSGVAHIP 350
                  M++ V  +P
Sbjct: 357 LPQTAGAMQAVVRALP 372


>UniRef50_C0GUA1 Geranylgeranyl reductase n=1 Tax=Desulfonatronospira thiodismutans
           ASO3-1 RepID=C0GUA1_9DELT
          Length = 368

 Score =  164 bits (416), Expect = 4e-39,   Method: Composition-based stats.
 Identities = 62/353 (17%), Positives = 121/353 (34%), Gaps = 53/353 (15%)

Query: 4   FDVAIIGLGPAGSALARKLA-----------GKMQVIALDKKHQCGTEGFSKPCGGLLAP 52
           +DV IIG GP                       M V  LDKK    +    K C G+L  
Sbjct: 5   YDVIIIGCGP----------AGATAALLLAAKGMDVAVLDKK----SFPRFKLCAGMLTQ 50

Query: 53  DAQRSFIRDGLTLPVDVIANPQIFSV-----KTVDVAASLTRNYQRSYININRHAFDLWM 107
                       L  ++     I  V      +       T + + SY+ ++R ++D   
Sbjct: 51  KTLDQCSLFYPELAHELKKRDIIRHVSSQYAISTGKKRLYTGSSKYSYVLVDRESYDQLW 110

Query: 108 KSLIPASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYP 167
              +  +    +     ++   + +           +    R+++GADG +S VR+ L  
Sbjct: 111 HEKVRETGASVYREQIVRVDIPESRVTAK-----NGRVFRGRFILGADGGSSRVRKTLAL 165

Query: 168 DHQIRK------YVAIQQWF-AEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGA-YP 219
           +  +R        +A++ +   ++   P +  +F   + + Y+WS         G     
Sbjct: 166 EKVVRPPWSKGSALALETFVSRQQAGFPDFPELFTGIVPDGYAWSFPGASRQRLGICSAV 225

Query: 220 MKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFIS 279
           +KDG+     + + ++       +         + P    +   G  N  L+G+AAG   
Sbjct: 226 VKDGRELRKIMLDLLAGQGVHLDEKEIRG---HVLPYGDYEKTPGFQNILLLGDAAGMAD 282

Query: 280 ASSLEGISYALDSTDILRSVLLKQPEKLNTAY-------WRATRKLRLKLFGK 325
               EGI YA  +  +    + +   + +              R +R+K F +
Sbjct: 283 PLLGEGIYYAHATGGLAARAVEECWSRNDRTADVYSSLLSDIIRDMRIKWFMR 335


>UniRef50_C6HZ38 Geranylgeranyl reductase n=1 Tax=Leptospirillum ferrodiazotrophum
           RepID=C6HZ38_9BACT
          Length = 414

 Score =  164 bits (415), Expect = 6e-39,   Method: Composition-based stats.
 Identities = 68/341 (19%), Positives = 114/341 (33%), Gaps = 24/341 (7%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           H D A++GLGPAGS   R LA          +        +KPCGG ++           
Sbjct: 16  HVDAAVVGLGPAGSTALRLLASAGISCIGIDRSH---FPRNKPCGGGVSARTLPLLPPGL 72

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLI-PASVEVYHDS 121
           L      I +    + +                  + R  FD  +      A  +V    
Sbjct: 73  LDEIPHQITSGISLTYRGGPSQNQDFGR--PIAYQVRRDQFDAALLDAAYRAGGQVMTGV 130

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPD--------HQIRK 173
                 RE  ++ ++       + I A  +  ADGA S + R L PD          +R 
Sbjct: 131 ETVSARREGREFVIVA----DHRVIRALSVFAADGATSRILRDLDPDSSRHVRENPSLRP 186

Query: 174 YVAIQQWFAEKHPVPF-YSCIFDNSITNCYSWSISKDGYFI-FGGAYPMKDGQTRFTTLK 231
           + + + +   ++P+   +  I    ++  Y+WS  K       G A  +           
Sbjct: 187 FTSAEAFGDLRNPIDDRHVGIDLGLVSGGYAWSFPKKDSSWGLGVAGFLGPLANPRKEFA 246

Query: 232 EKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALD 291
             + + Q   GK       T   P+            FL+G+A G +     EGI YA+ 
Sbjct: 247 RYLESRQATVGKAEVL---TWPLPNYRSVRHGRISGLFLVGDAGGILDPFLGEGIYYAIL 303

Query: 292 STDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCL 332
           S       L+ +  + + A       L  + + + VK    
Sbjct: 304 SATRGAEALIHELSRKDIA-PETAAGLASQAYARFVKGTLW 343


>UniRef50_A1HMV3 FAD dependent oxidoreductase n=1 Tax=Thermosinus carboxydivorans
           Nor1 RepID=A1HMV3_9FIRM
          Length = 458

 Score =  164 bits (415), Expect = 6e-39,   Method: Composition-based stats.
 Identities = 55/327 (16%), Positives = 100/327 (30%), Gaps = 42/327 (12%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGG--LLAPDAQRSF 58
           + +D  ++G GPAGS  A  +A   + V+ L++    G    +K CGG  ++A    + F
Sbjct: 31  KKYDAIVVGAGPAGSTAAYFMAKEGLDVLLLER----GPYPGAKCCGGVSIIAEHVHKLF 86

Query: 59  IRDGLTLPVDVIANPQIFSVKTVDVAASLTRNY------QRSYININRHAFDLWM-KSLI 111
                  P + I   Q +   T D   +             +   I R  F  W+    I
Sbjct: 87  PNFWEECPYERIVTDQAYWWMTEDSILTARFRSTKLAAAPYNRFTIKRVNFYKWLTAKAI 146

Query: 112 PASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQI 171
            A   +  +    ++  +  +   +  +        A  ++ ADGANSM+        QI
Sbjct: 147 SAGTTLLLNHHVSEVLFDGQQAIGVHVSPPQNSDFIADIIILADGANSMLAERAKLAPQI 206

Query: 172 RKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSI-----------------SKDGYFIF 214
                   +  E   +P        ++   +   I                 +    F  
Sbjct: 207 SPR-NFALYVKETIALPAKVIEERFNLLPGHGTIIGLIGYPTAGFNGTGSIHTFKDSFNI 265

Query: 215 GGAYPMKDGQTRFTTLKEKMSAFQFQ------FGKTVKSEKCTVLFPSRWQ--DFVCGKD 266
                + D         + +   +               E    L P             
Sbjct: 266 NVGISLADLAKAGFNPNDLLERIKKHPHMQPLLDGGTTIEYGAALIPEGGYYAMPELVHP 325

Query: 267 NAFLIGEAAGFISASSLEGISYALDST 293
              +IG+AA  ++     GI+ A+ S 
Sbjct: 326 GLMIIGDAASLVNGVH--GINLAMWSG 350


>UniRef50_A5G7E3 FAD dependent oxidoreductase n=2 Tax=Geobacter RepID=A5G7E3_GEOUR
          Length = 432

 Score =  164 bits (415), Expect = 6e-39,   Method: Composition-based stats.
 Identities = 58/370 (15%), Positives = 113/370 (30%), Gaps = 49/370 (13%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPD--AQRSF 58
           + +   ++G GPAGS+ A  +A   + V  +++    GT    K   G +     +    
Sbjct: 3   KQYQAIVVGAGPAGSSAALTMARAGLDVALVER----GTFPGEKNMFGGILHRMTSIEEL 58

Query: 59  IRDGLT-LPVDVIANPQIFSV------KTVDVAASLTRNYQRSYININRHAFDLWMKS-L 110
           + D  T  P++     +  +         V    +       +   + R  FD W+    
Sbjct: 59  MPDFWTKAPLERHIAKKGTTFMTAEASFNVQHETTNFDRAPYNGYTVFRPRFDRWLAEEA 118

Query: 111 IPASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQ 170
           + A   +   S    +  ++D+        G    I A  ++ ADG  S   +       
Sbjct: 119 VKAGATLITRSTVDDLIYKNDRI-AGVSILGRTGQIKAPVVIAADGVLSFTAQKAGLRRP 177

Query: 171 IRKYVAIQQWFAEKHPVPFYSCIFDNSIT----NCYS--------------WSISKDGYF 212
                A Q     K  +     + D+         ++              +  +     
Sbjct: 178 KFN--ADQMAVGVKALIDMPREMIDDRFGLVRDQGFANEFVGCTGGVRGGGFLYTNYDSL 235

Query: 213 IFGGAY----PMKDGQTRFTTLKEKMS--AFQFQFGKTVKSEKCTVLFPSRWQD--FVCG 264
             G  +        G+T +  L E M               E    + P    +      
Sbjct: 236 SIGLVFHLASLRTSGKTPYDLLNEFMEQPQVAKLVRGGRLQEYSAHVIPEGGYNMIPELA 295

Query: 265 KDNAFLIGEAAGFISA--SSLEGISYALDSTDILRSVLLKQ---PEKLNTAYWRATRKLR 319
            +   + G+AA   +A   +LEGI+ A  S  +    +++     +       R   +L 
Sbjct: 296 GNGILVAGDAAALCNATGVNLEGINLASHSGILAGKTVIEAHQQQDFSLKTLKRYKERLD 355

Query: 320 LKLFGKIVKS 329
           L    K +K 
Sbjct: 356 LSWVMKDLKG 365


>UniRef50_A8LZN8 Tryptophan halogenase n=2 Tax=Micromonosporaceae RepID=A8LZN8_SALAI
          Length = 413

 Score =  163 bits (414), Expect = 8e-39,   Method: Composition-based stats.
 Identities = 47/360 (13%), Positives = 99/360 (27%), Gaps = 32/360 (8%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
            +DV ++G GPAG+  A  LA +   I L ++ +          G  L      +    G
Sbjct: 7   EYDVIVVGGGPAGACTAGLLALEGHRILLLEREKFPRYHV----GESLITGVVPTLTALG 62

Query: 63  LTLPVDVIANPQIFSVKTVDVA----------ASLTRNYQRSYININRHAFDLWMKSLIP 112
           L   +  +     +    +               +          + R  FD  +     
Sbjct: 63  LLDRMAELRFQVKYGGSLLWGENQTEPWSFRFREIRGGRYEYAWQVRRAEFDAMLLDRAR 122

Query: 113 A-SVEVYHDSLCRKIWREDDK-WHVIFRADGWEQHI--TARYLVGADGANSMVRRHLYPD 168
              V V   +  R    + D+   V ++  G    +   A  +V A G +  + R     
Sbjct: 123 ELGVHVVEGATVRDALTDGDRLAGVRYQLKGESGSVPARATMVVDASGQHRWLGRRFGLV 182

Query: 169 HQIRKY--VAIQQWFAE--KHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDG- 223
                   VA+  ++    ++P      +   S    + W           G     D  
Sbjct: 183 DWYDDLRNVAVWSYWQGALRYPGEHEGDLLTESCRQGWLWYAPLSPELTGIGYVTTSDRL 242

Query: 224 -------QTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAG 276
                  +        + S   +      + +         +           L+G+AA 
Sbjct: 243 VASGLTPEQLLERHIAESSEVSWLTAGAKRVDIYRAARDWSYTCQQFSGPGWVLVGDAAA 302

Query: 277 FISASSLEGISYALDSTDILRSVLLKQPEKLNTAYW--RATRKLRLKLFGKIVKSRCLTA 334
           FI      G++ A+ +   +   + +     +      +          G +++      
Sbjct: 303 FIDPLLSAGVTLAMRAASSVAKAVHETLTAPDKERHVMKDYEDRYRDFLGSLLELVRFFY 362


>UniRef50_Q467V5 Putative uncharacterized protein n=3 Tax=Methanosarcina
           RepID=Q467V5_METBF
          Length = 416

 Score =  163 bits (413), Expect = 9e-39,   Method: Composition-based stats.
 Identities = 50/338 (14%), Positives = 108/338 (31%), Gaps = 33/338 (9%)

Query: 16  SALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQ 74
           S  AR  A    +V+ L++    G+      C GLL+  A        L    + + N  
Sbjct: 15  STAARYAALNGAKVLLLEEHAFIGS---PVSCTGLLSTRAVAECE---LKPSDEFVFNSV 68

Query: 75  IFSVKTVDVAASLTRN-YQRSYININRHAFDLWMK-SLIPASVEVYHDSLCRKIW----- 127
             +         L  +  Q     ++R  FD  +    +   VE+   +    +      
Sbjct: 69  RGAFVYAPDGQCLPIDGKQTKAYVVSRKNFDRNLAVMAVEEGVELSLRTRAVGLEMPSPK 128

Query: 128 -----REDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFA 182
                +++    +    +G  + I A  ++GADG  S +  +   +        IQ    
Sbjct: 129 TDKEGQQNSTVKLKVLKNGKPETICASAVIGADGVKSRIASYAGLEKPASVLPGIQIEAP 188

Query: 183 EKHPVPFYSCIFDNSI-TNCYSWSISKDGYFIFGGAYPMK--------DGQTRFTTLKEK 233
                  +  +F  S+    ++W++  +                    +  +  + L++ 
Sbjct: 189 YASDDSDFVELFPGSVAPGFFAWTVPVNEKISRIALALEPGLAWKNGHEESSPLSYLEKF 248

Query: 234 MSAFQFQFGK--TVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALD 291
           + +      +      +      P          D   L+G+AAG   ++S  G+     
Sbjct: 249 LHSNPHVKARYSGCMLDFVVGGIPIG-PQKKTVSDGVLLVGDAAGQTKSTSGGGVYTGAF 307

Query: 292 STDILRSVLLKQPEKLNTAYWR--ATRKLRLKLFGKIV 327
           +  I   V  +   + +T+  R     +L  K   + +
Sbjct: 308 AAKIAGKVAAQAALEGDTSAKRLSEYDQLWRKGLEREL 345


>UniRef50_Q2JXT2 2-octaprenyl-6-methoxyphenol hydroxylase n=2 Tax=Synechococcus
           RepID=Q2JXT2_SYNJA
          Length = 414

 Score =  163 bits (413), Expect = 9e-39,   Method: Composition-based stats.
 Identities = 57/378 (15%), Positives = 108/378 (28%), Gaps = 30/378 (7%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           +DV I+G G AG  LA  L G    +AL +          +P    L+P + R F   G+
Sbjct: 15  YDVIIVGGGIAGLTLACALQGSGLRLALIEAQSAEA-VRQRPLAYALSPLSIRIFRAIGV 73

Query: 64  TLPVDVIANPQIFSVKT-VDVAASLTRNYQRSY-----ININRHAFDLWMKSLIPAS--V 115
              +     P    + T  D    +T   +                   ++  + A   +
Sbjct: 74  WEALAPHITPFAQVILTDADAPQRVTFRPEDVGETAVFYCGEHARLQQVLQERVAADPQI 133

Query: 116 EVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYV 175
             ++++    +   +    V        + + A  +V ADG  S VR+          Y 
Sbjct: 134 TCHYEARVESVTYGEAAAEVELETTQGRRRLAASLVVAADGLRSQVRQRAGIPSDGWDYW 193

Query: 176 AIQQWFAEKHPVPFYSCIFDNSITNC-YSWSISKDGYFIFGGAYPMKDGQTRFTT----- 229
                          +  ++       ++               P +  +          
Sbjct: 194 QSCITALVAPAQDHQNVAYERFWPAGPFAILPLPGNRCQVVWILPHEQAKATLALSQADF 253

Query: 230 LKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYA 289
           L E    +  Q G         V      Q     +    L+G+AA      + +G++  
Sbjct: 254 LAEMQRYYGDQGGYLTLLNPPQVFPARLRQSRRYYQHRLALVGDAAHHCHPVAGQGLNLG 313

Query: 290 LDSTDILRSVLLKQPEKLNT--------------AYWRATRKLRLKLFGKIVKSRCLTAP 335
           +     L  VLL    +                  +      L   L  +   +      
Sbjct: 314 IRDAAALAQVLLDAWRRQEDLGEVQVLRRYGRRRRWENWVVLLFTDLLTRTFSNSYWPLV 373

Query: 336 ALRKWIMRSGVAHIPQLK 353
            LR+ ++  G+   P L+
Sbjct: 374 VLRRLVL-IGMIRFPPLR 390


>UniRef50_A4JRJ4 Tryptophan halogenase n=6 Tax=Proteobacteria RepID=A4JRJ4_BURVG
          Length = 430

 Score =  163 bits (413), Expect = 1e-38,   Method: Composition-based stats.
 Identities = 53/343 (15%), Positives = 95/343 (27%), Gaps = 27/343 (7%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
              DVAIIG GP+G+  A  L    + + + ++            G  L P + R     
Sbjct: 7   NSVDVAIIGAGPSGAVAAALLRNAGRSVLVLERQHFPRFSI----GESLLPQSMRYLEEA 62

Query: 62  GLTLPVDVIANPQIFSVKTVDVAASLTRNYQR-------SYININRHAFDLWMKSLIPA- 113
           G+   V             V      + +++        +   + R AFD  +       
Sbjct: 63  GMLQAVVEAGFQFKNGAYFVHRDRMSSFDFRDKFSDGWGTAYQVERAAFDDLLIRCAEKQ 122

Query: 114 SVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQ--I 171
             +V      R     D     +    G E  + A +++ A G   ++ R L  +    +
Sbjct: 123 GAQVRFGHAVRAFHAGDTPRLDVVDEAGHEYSVQASFVLDASGFGRVLPRLLGLEAPTGL 182

Query: 172 RKYVAIQQWFAEKHP------VPFYSCIFDNSITNCYSWSISKDGYFIFGGA-------Y 218
               AI     ++ P            +        Y      +G    G          
Sbjct: 183 PTRAAIFSHVEDRLPAGSTDRDKICIAVHPERRDVWYWMIPLTNGRSSVGCVADAAFLDV 242

Query: 219 PMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFI 278
           P  + +     L +         G          +                L+G A  F+
Sbjct: 243 PEAEQEALLRELLQTEPTLSRLVGSKPFVMPVRRICGYASNVESLHGHGYALLGNAGEFL 302

Query: 279 SASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLK 321
                 G++ AL S  +  + L +Q       + R       K
Sbjct: 303 DPIFSSGVTIALRSAHLAVATLERQLRGETVDWARDYDVALRK 345


>UniRef50_A7GPR1 FAD dependent oxidoreductase n=1 Tax=Bacillus cytotoxicus NVH
           391-98 RepID=A7GPR1_BACCN
          Length = 455

 Score =  163 bits (412), Expect = 1e-38,   Method: Composition-based stats.
 Identities = 54/369 (14%), Positives = 111/369 (30%), Gaps = 51/369 (13%)

Query: 1   MEHFDVAIIGLGPAGSALA-RKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           ++  +V I+G G +GS+ A R L   ++ + +DK             G  L+P       
Sbjct: 3   IKQREVVIVGAGVSGSSTAIRLLKQGIRPLMIDKAIFPRE-----VVGEGLSPVICEYLK 57

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAAS--------------LTRNYQRSYININRHAFDL 105
              +   ++     +  S++ V  +                   +      N+ R  FD+
Sbjct: 58  ELDVLEEINQGGFLKKSSLQLVSPSGHKSYAAVDFNKDIYNDRVHSSPWGFNVRRKDFDM 117

Query: 106 WMKSLIPA-SVEVYHDSLCRKIWREDDK---WHVIFRADGWEQHITARYLVGADGANSMV 161
            + +       E+   +  +KI  +++      VI   DG +  I    ++   G  S +
Sbjct: 118 VLFNKAKELGAEILEGTSLKKILTDENGNINGVVITNIDGNDVEIKTNLVIDCSGRTSQL 177

Query: 162 RRHLYPDHQIRKY-------VAIQQWFAEKHPVP--------FYSCIFDNSITNCYSWSI 206
            +       +           AI+ +F   +  P          + +      +C+ W I
Sbjct: 178 AKQFKLRAPLENIFDGQWANYAIRCYFKNVNLEPLKRDVQDYDLATVNILPDADCWYWVI 237

Query: 207 S-KDGYFIFGGAYPMK---------DGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPS 256
             ++  F  G     K         D    +  L EK                  V    
Sbjct: 238 PLEENLFSIGFVARSKTKNILDGYNDKLKAYRELIEKHPVLNEVVKDAEMLNDVAVTSRL 297

Query: 257 RWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQPEKLNTAY--WRA 314
              +     +    +G+A  F   +   G++ AL ++     V  K  +  + +Y     
Sbjct: 298 GHMNTKMAGNGFMCVGDAGFFADPAWATGVTVALLTSKKAAEVCEKAIQSKDFSYKILNE 357

Query: 315 TRKLRLKLF 323
                    
Sbjct: 358 YEVFYRNYL 366


>UniRef50_B5HTB3 Alkylhalidase n=3 Tax=Actinomycetales RepID=B5HTB3_9ACTO
          Length = 532

 Score =  163 bits (412), Expect = 1e-38,   Method: Composition-based stats.
 Identities = 49/347 (14%), Positives = 96/347 (27%), Gaps = 32/347 (9%)

Query: 16  SALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQI 75
           S  +  LA   + + L +  +          G  L         + G+   ++     + 
Sbjct: 20  SMTSTLLAQYGKRVILFEAAKFPRYHI----GESLLSGTADLLKKIGVLEKLENAGFIKK 75

Query: 76  FSVKTVDVAASLTRN---------YQRSYININRHAFDLWMKSLIPA-SVEVYHDSLCRK 125
           + V+ V                         + R  FD  +        V+   +     
Sbjct: 76  YGVEWVWGERREPWTVYFKDALAMPYDYGYQVERGPFDQMLLENAREHGVDAREEHRVTD 135

Query: 126 IWREDDK-WHVIFR-ADGWEQHITARYLVGADGANSMVRRHLYPD--HQIRKYVAIQQWF 181
               DD    V +R AD     +TAR+LV + G   +V + L+        K +A+  ++
Sbjct: 136 FVIGDDGTVRVDYRDADDKPGSVTARWLVDSSGQGGLVTKRLHQQEWDPYLKNMAMWTYW 195

Query: 182 AEKHPVP--FYSCIFDNSITNCYSWSIS-KDGYFIFGGAYPMKDGQTRFTT--------L 230
                         F  +    + W I  +D     G     +                 
Sbjct: 196 RGAERPAGLDAGNTFLPTFDEGWWWFIPLRDDITSVGVVVDRQSYLKNKEAGLDNYYRSC 255

Query: 231 KEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYAL 290
            E+      +     + +K        +       D    +G+AA FI      G+  ++
Sbjct: 256 LERTPELAERLQGAEQVDKMHAQRDWSYIYDRFSGDGYIAVGDAACFIDPLFSTGVHLSM 315

Query: 291 DSTDILRSV---LLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTA 334
            S  +  +    +L +PE               K F ++        
Sbjct: 316 LSGYLAATAVNTILDKPELGRDTVLDFYESAYRKEFERLRAQVYFLY 362


>UniRef50_Q6EVQ8 Putative FAD-dependent monooxygenase n=1 Tax=Yersinia
           pseudotuberculosis RepID=Q6EVQ8_YERPS
          Length = 410

 Score =  163 bits (412), Expect = 1e-38,   Method: Composition-based stats.
 Identities = 56/342 (16%), Positives = 113/342 (33%), Gaps = 27/342 (7%)

Query: 4   FDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +DV I+G    G+A +  L    + V  ++K        + K C   + P A     + G
Sbjct: 3   YDVVIVGGSATGAASSILLRKLGLSVRVIEK--LPSASSYKKLCTHFIQPSAVPVLSQLG 60

Query: 63  LTLPVDVIANPQIFSVKT-----VDVAASLTRNYQRSYININRHAFDLWMKSLI-PASVE 116
           +    +   + +  +        +D       + Q+  +N+ R   D  ++       VE
Sbjct: 61  MAHLAERDYSVRTRATFITPAGIIDPEGFYGTDSQQCALNLERSVLDPALRQQAYECGVE 120

Query: 117 VYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQ--IRKY 174
           + +      + R    W +          I  R+L+ ADG  S++ R L    Q      
Sbjct: 121 IGYAERVMGVQRSPQGWQLTVERTEETFSIEGRFLIAADGRMSLLARLLDNPMQSYENHR 180

Query: 175 VAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTT----- 229
                + +          +F +   N  ++            AY  K+   ++       
Sbjct: 181 ATFFAYCSGIEAPADNRSLFAH-HQNGMAFLYPLINGRTLLSAYISKEISQQWQQHDVKA 239

Query: 230 -LKEKMSAFQFQFGKTVKSEKCTVL----FPSRWQDFVCGKDNAFLIGEAAGFISASSLE 284
            L E  +           + +  V+    +P+  +  VC       IG+AA  +   S  
Sbjct: 240 SLVEFFAGVPAMPAMNNVTFETQVMGYRDYPNLTRQPVCQD--VAFIGDAAQSLDPMSGV 297

Query: 285 GISYALDSTDILRSVL---LKQPEKLNTAYWRATRKLRLKLF 323
           G S+AL +  +L   +   L+          +  ++   + F
Sbjct: 298 GCSFALQTAAMLAQSVEVSLQHGVVNTQLALQTYQRQFNEYF 339


>UniRef50_Q0RKB9 Putative 3-(3-hydroxy-phenyl)propionate hydroxylase,
           FAD/NAD(P)-binding n=2 Tax=Actinomycetales
           RepID=Q0RKB9_FRAAA
          Length = 572

 Score =  162 bits (411), Expect = 2e-38,   Method: Composition-based stats.
 Identities = 67/376 (17%), Positives = 121/376 (32%), Gaps = 27/376 (7%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           E  DVAI+G GP G  LA  L    +  + LD++               +  ++ R+F  
Sbjct: 4   ESADVAIVGAGPCGVTLANLLGTYGVSTVVLDRESGVIDYPR----AVAVDDESLRTFQT 59

Query: 61  DGLTLPV--DVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPA----- 113
            GL   V  D I N  I    +     +      + +    R+ F   +           
Sbjct: 60  VGLVHEVLADCIQNAPIRYHNSQGKVLAHVGPSGQPFGWPRRNLFFQPLMEATLRRGLDR 119

Query: 114 --SVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQI 171
              V +Y D+    + R  D   +     G +  +TARYLVGADG  S VRR +  +   
Sbjct: 120 FPGVRLYADTEVTGLERTADGVVLTGTRGGEDVTVTARYLVGADGGRSFVRRSVGVELVG 179

Query: 172 RKYVAIQQWFAEKHP--VPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMK-DGQTRFT 228
               +               YS +  + +    +  +            P + D +    
Sbjct: 180 ETNPSKWLVVDVSDDQLDAPYSAVHCDPVRPSMTIPLPYGHRRFEFKLLPDETDERMVTD 239

Query: 229 TLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISY 288
            +   + A  ++     +  +  + +              FL G+AA        +G++ 
Sbjct: 240 EVVMGLLAKHYRDTPMPRISRRRIYWHHSRIATTFRVGPVFLAGDAAHLQPPFFGQGMNS 299

Query: 289 ALDST-----DILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALR----- 338
            +         +   +  +  E+L  +Y    R     +     +   +  P  R     
Sbjct: 300 GIRDATNLGWKLAAVLAGRADERLLDSYDAERRAHAETMVSFATRVGAMYEPRNRLTERV 359

Query: 339 KWIMRSGVAHIPQLKD 354
           +     GV  IP  +D
Sbjct: 360 RDAFFVGVQRIPGARD 375


>UniRef50_B5HZJ0 Pentachlorophenol 4-monooxygenase n=2 Tax=Streptomyces
           RepID=B5HZJ0_9ACTO
          Length = 539

 Score =  162 bits (411), Expect = 2e-38,   Method: Composition-based stats.
 Identities = 51/355 (14%), Positives = 114/355 (32%), Gaps = 24/355 (6%)

Query: 5   DVAIIGLGPAGSALARKL-AGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           DV +IG GP+G+A+A  L    + V  +D+         +K     + P +       G 
Sbjct: 38  DVLVIGAGPSGTAVAIDLVRRGLDVRIVDRSPHAFDGSRAK----GVQPRSLEVLEDLGA 93

Query: 64  TLPV----------DVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPA 113
              V           + A P     K      +       +   I +   D  + + +  
Sbjct: 94  LDEVLAGGSTYPRLGIHAGPLGVPWKMFPHREAAPDIPYPNTWLIPQFRTDRALHTRLSE 153

Query: 114 -SVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHL-----YP 167
              E+       ++ + +D            + I ARY+VGADG +S+VR+ L       
Sbjct: 154 LGREIEFGRELTELTQNEDTVVATVAGADGTEEIVARYVVGADGGSSVVRKQLEIGFVGT 213

Query: 168 DHQIRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAY-PMKDGQTR 226
             +  + + +           ++            +  +     F +     P ++   +
Sbjct: 214 TDESDRMLIVDASVTGLARNRWHMWPGRGGRFIG-ACPLPHSDMFQWMIRLKPDEEPPAK 272

Query: 227 FTTLKEKMSAFQFQFGKTVKSEKC-TVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEG 285
              + +++ +        +      +V  P+       G+   FL+G+AA   + +  +G
Sbjct: 273 RDDIVQRIHSHTRDRRIQLHDIHWTSVFRPNIRLAKNYGRGRVFLVGDAAHVHTPAGAQG 332

Query: 286 ISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKW 340
           ++  +     L   + +     N A        R  +   ++         + + 
Sbjct: 333 LNTGVQDGYNLGWKISQVLAGANAALLDTYEAERQPIAAGVLGLSTAKWGGIARL 387


>UniRef50_B5Y9L9 FAD binding domain, putative n=1 Tax=Coprothermobacter
           proteolyticus DSM 5265 RepID=B5Y9L9_COPPD
          Length = 370

 Score =  162 bits (411), Expect = 2e-38,   Method: Composition-based stats.
 Identities = 59/348 (16%), Positives = 121/348 (34%), Gaps = 24/348 (6%)

Query: 5   DVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG- 62
           D+ I+G   +G  LA  +    ++ + +++K +  +     P  GL+ P   +   +   
Sbjct: 10  DLLIVGASFSGLTLAYSVHNPGLRSLIVERKRRLWS-----PSTGLITPPTLKLLEQVFP 64

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSL 122
             +P+          V   DV   L  + +     +++ +F    +  +P+S  +     
Sbjct: 65  FGIPIIRAFTSMK--VIFKDVGEVLLSSREPFLFLLDKDSFFSAAEEHLPSSFTLALGCS 122

Query: 123 CRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFA 182
             K   +        +    E  I    LVGADGA S V +              +   +
Sbjct: 123 FVKTENK----TAKVQTHYTETTIRYDLLVGADGALSKVAKSSGLPLVKEWLYGYEWKIS 178

Query: 183 EKHPVPFYSCIFDNSITNCYS-WSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQF 241
                 F + + D +++  Y  W    +G    G A        R   ++  M  + F F
Sbjct: 179 RPAEDDFITFVVDPTVSRAYGIWMFPVNGGVRIGLA---SKKPLRKIDVQSIMKQY-FSF 234

Query: 242 GKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLL 301
              +   K     P         K++  L+G+AAG       +GI  A+ S       + 
Sbjct: 235 DGPLLDYKGGA-IPISGPVRAPFKEDVILLGDAAGLCGPFLGDGIQTAVKSGIAAARAVE 293

Query: 302 KQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAHI 349
           +    +  +Y    +K       K +K + L      +++ ++ +  +
Sbjct: 294 Q--PNVGPSYVELLKKT---EVTKYLKQQALLRSIWDRFVSKNTLKRL 336


>UniRef50_D0L4V5 Geranylgeranyl reductase n=6 Tax=Actinomycetales RepID=D0L4V5_GORB4
          Length = 435

 Score =  162 bits (410), Expect = 2e-38,   Method: Composition-based stats.
 Identities = 50/358 (13%), Positives = 97/358 (27%), Gaps = 38/358 (10%)

Query: 26  MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT---LPVDVIANPQIFSVKTVD 82
             V+ +D           K CG  L P A     R GL         I    +       
Sbjct: 48  HDVVLVD----AAVFPRDKTCGDGLTPRAVAELDRLGLGHFLADRPRIEGLHLHGWGADK 103

Query: 83  VAASLTRNYQRSYININRHAFDLWMKS-LIPASVEVYHDSLCRKIWREDDKWH-VIFRAD 140
                   +      + R   D  +++  +     +   +    +    D+   V   + 
Sbjct: 104 RVPWPAGRFPAHGSAVARTELDDAIRAFAVSKGARMIQGAKAVDVTMSGDRIESVTLSSA 163

Query: 141 GWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEKHPVPFYSCIFD----- 195
                + A +++ ADG  S + + L  +        +      +      + +       
Sbjct: 164 AGTSAVRAEHVIVADGVRSGLGKILGREWHRDTAYGVAARAYVRSGRADDAWMGSHLELR 223

Query: 196 ---NSITNCYSWSIS----KDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKTVKSE 248
               ++   Y W        DG    G        +     L+  +  +          +
Sbjct: 224 GPEGTLLPGYGWVFPLGSAGDGLLNVGVGALATSKRPAHMQLRPVLEFYTDMVRDEWAVD 283

Query: 249 KCTV-----LFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLL-- 301
              V     L P           N  LIG+AA  ++  + EGI YAL++  +   ++   
Sbjct: 284 GSPVRLTSALLPMGGAVSGVAGRNWMLIGDAAACVNPLNGEGIDYALETGRLAIELIDDT 343

Query: 302 KQPEKLNTAYWRATRKLRLKLFGKIVKS----------RCLTAPALRKWIMRSGVAHI 349
           +      T +           F    +             L  P +R   + S V  +
Sbjct: 344 RADPDHTTRWPAILVDHYGLAFSAARRLAGVLTVPQAVPTLGRPGIRSARLMSMVVRV 401


>UniRef50_B8G0W1 Electron-transferring-flavoprotein dehydrogenase n=4
           Tax=Clostridiales RepID=B8G0W1_DESHD
          Length = 430

 Score =  162 bits (410), Expect = 2e-38,   Method: Composition-based stats.
 Identities = 59/343 (17%), Positives = 118/343 (34%), Gaps = 41/343 (11%)

Query: 3   HFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
            FD  ++G G AG+  A  LA   ++V+ +++ +  G++  +   GG +   +    + +
Sbjct: 5   RFDAIVVGGGIAGTVTAYLLAKEGLEVMLVERGNYSGSKNVT---GGRIYSHSLEKIMPN 61

Query: 62  GLTL-PVDVIANPQIFSVKTVDVAASLTRNY------QRSYININRHAFDLWMK-SLIPA 113
                PV+     +  S+ T +   +L  +        R   ++ R  FD W+      A
Sbjct: 62  FAQEAPVERKITREKISLMTEESNVTLDFSSTKLGEQGRDSYSVLRGVFDQWLATKAEEA 121

Query: 114 SVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRK 173
            V++        +   + K   I      E  + A   + ADG NS++ + L    +++ 
Sbjct: 122 GVQIIPGIRVDDLILREGKVCGII---AGEDELEANVTILADGVNSLLAQKLGFRDELQP 178

Query: 174 Y-VAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISK---------------DGYFIFGGA 217
             VA+      + P       F+       SW  +                      G  
Sbjct: 179 NQVAVGAKEIIELPAQTIEDRFNCKKGEGTSWLFAGTPSAGKVGGGFIYTNKESISLGVV 238

Query: 218 YPMKDGQTRFTTLKEKMSAFQFQF------GKTVKSEKCTVLFPSRW--QDFVCGKDNAF 269
             + +      TL + +  F+               E    L P                
Sbjct: 239 STLSELIKANKTLPQMLEDFKAHPSIEPLIKGGKMVEYSGHLVPEGGLTMVPKIIGHGVL 298

Query: 270 LIGEAAGFI--SASSLEGISYALDSTDILRSVLLKQPEKLNTA 310
           ++G+AAGF      ++ G+ +A+ S +     +LK  E  + +
Sbjct: 299 VVGDAAGFCINLGYAVRGMDFAVGSAECAAKAVLKAKEAQDFS 341


>UniRef50_B9XGA7 Tryptophan halogenase n=1 Tax=bacterium Ellin514 RepID=B9XGA7_9BACT
          Length = 418

 Score =  162 bits (410), Expect = 2e-38,   Method: Composition-based stats.
 Identities = 53/346 (15%), Positives = 108/346 (31%), Gaps = 35/346 (10%)

Query: 21  KLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKT 80
            LA   + + + +K            G  L P  Q+ F   G++  ++     + +  + 
Sbjct: 23  YLAKAGKRVLVLEKEHFPRFHI----GESLLPYNQQIFREMGVSPALEAAGFVKKYGAQF 78

Query: 81  VDVAASLTRNY---------QRSYININRHAFDLWM-KSLIPASVEVYHDSLCRKIWRED 130
                S +  +         +   + + R AFD  + K    +  E+       K   + 
Sbjct: 79  HIGNGSKSIGFVFRQGKMTREPEAMQVERAAFDHLLMKHARSSGAEIREGWTVAKYSSDC 138

Query: 131 DKWHVIFR-ADGWEQHITARYLVGADGANSMVRRHLYPD--HQIRKYVAIQQWFAEK--H 185
               +  R   G  Q   A++L+ A G  ++          H   K VA+   F      
Sbjct: 139 CGVSIDARDQSGQSQIFKAKFLIDASGRGNVTGNQDGQRQFHPKLKKVAVFGHFTGVKVD 198

Query: 186 PVPFYSCIFDNSITNCYSWSIS-KDGYFIFGGAYPMKDGQTRFTTLKEKMSA-------F 237
           P           + N + W I         G     ++      +  E  +         
Sbjct: 199 PGERGGDTVIVRLENKWFWLIPISREKTSVGCVMDQEEFAAAKQSPAEIFNRIVQSSQPM 258

Query: 238 QFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILR 297
             +      +          + +          IG+AAGF+      G+  A+ S  +  
Sbjct: 259 VQRMSDAKSAGNFQTTTDFSYTNKSFTGQRLIRIGDAAGFMDPIFSAGVYLAMFSGKLAA 318

Query: 298 SVLLKQPEK------LNTAYWRATRKLRLKLFGKIVKSRCLTAPAL 337
            +++K  E       L  AY +  R   ++ + ++V++   T P +
Sbjct: 319 QLVIKSLEGHHDGSRLMKAYEKRVRS-SMRFYWEMVEN-FYTKPFM 362


>UniRef50_C7M2T6 Geranylgeranyl reductase n=1 Tax=Acidimicrobium ferrooxidans DSM
           10331 RepID=C7M2T6_ACIFD
          Length = 436

 Score =  161 bits (409), Expect = 2e-38,   Method: Composition-based stats.
 Identities = 59/359 (16%), Positives = 111/359 (30%), Gaps = 32/359 (8%)

Query: 16  SALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQ 74
           ++ A  LA   + V+ L++K         K CG  L P +       GL   ++   +  
Sbjct: 23  ASCAHWLAMRGIDVVVLERKQ----FPRDKVCGDGLTPRSVVQLEALGLGAELEARFHRY 78

Query: 75  IF-----SVKTVDVAASLTRNYQRSYININRHAFDLWMK-SLIPASVEVYHDSLCRKIWR 128
                    +T+D+                R   D  +  +       V       ++ R
Sbjct: 79  EGLRAVAFGRTLDIPWPNHPLLPSYGFVARRRELDALVVGAAADRGATVLFGHEGIELER 138

Query: 129 EDDKWHVIFRA---DGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEKH 185
             +    +      DG    + AR++V A+G+N+ + R L       + + +        
Sbjct: 139 RGNGISAVLARRTNDGAVVRVRARWVVLAEGSNARLARSLGAIRDTSQPLGLAIRTYLPS 198

Query: 186 PVPFYSCIFD--------NSITNCYSWSIS-KDGYFIFGGAYPMKDGQTR----FTTLKE 232
                  I            +   Y W     DG    G       G  R     T L  
Sbjct: 199 SRSDEPWIESALDVRDESGRVMPGYGWVFPMGDGSVNIGFGLLTNQGAWRHVNTTTELAR 258

Query: 233 KMSAFQFQFGKTVK----SEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISY 288
            +   + ++G  V+    ++      P           N  L+G+ A  I+  + EGISY
Sbjct: 259 FVDRVRDRWGLDVEHPLLAKPVGGKLPMGTTIKPVQGSNYLLVGDTAATINPFNGEGISY 318

Query: 289 ALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALR-KWIMRSGV 346
           AL++  +  +++ +     +         L    +G            +    +M  GV
Sbjct: 319 ALETGRLAATLIAEARRTDSDHPLTRYPALLGGHYGTYYALGRRFVRLISDPRVMAPGV 377


>UniRef50_B4V6H8 Pentachlorophenol 4-monooxygenase n=6 Tax=Streptomyces
           RepID=B4V6H8_9ACTO
          Length = 478

 Score =  161 bits (409), Expect = 2e-38,   Method: Composition-based stats.
 Identities = 60/344 (17%), Positives = 102/344 (29%), Gaps = 28/344 (8%)

Query: 5   DVAIIGLGPAGSALARKL-AGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           DV I+G GP G ALA  L    +  + +++  +       K     L P     F   G+
Sbjct: 14  DVLIVGAGPTGLALAVDLTRRGVHALVVERADRLFPGSRGK----GLQPRTLEIFDDLGV 69

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQRSY-----------ININRHAFDLWMKSLIP 112
              V   A P    V   D      +    +              + +      +++ + 
Sbjct: 70  LDAVRASAGPYPIGVIWQDGQRKGEQRMSDATEATEAAPYDEPWMLPQWRTQEILRARLE 129

Query: 113 A-SVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQ- 170
               EV        I ++ D     F        + ARY V  DG  S VRR L      
Sbjct: 130 ELGGEVVFGRELVGIAQDPDGVTASFATGAP---VRARYAVAGDGGRSTVRRALGIGMTG 186

Query: 171 --IRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFT 228
             +     +               +F  + T  +       G   F  A    +G     
Sbjct: 187 ESVDPNPMLVADVRITGLDRDVIHMFPPTDTEGFLAVFPLAGTEDFQVAAQFPEGTDADL 246

Query: 229 TL---KEKMSAFQFQFGKTVKSEKCTV-LFPSRWQDFVCGKDNAFLIGEAAGFISASSLE 284
           TL   +E  +A      + V   +      P         +   FL G+AA   S +  +
Sbjct: 247 TLDGIREVFAARTHLSPEAVTEVRWASDFRPRAALADRFREGRVFLAGDAAHIHSPAGGQ 306

Query: 285 GISYALDSTDILRSVLLKQPE-KLNTAYWRATRKLRLKLFGKIV 327
           G++ ++     L   L        + +      + RL     ++
Sbjct: 307 GLNTSVQDAYNLGWKLGAVLRGGADPSLLDTYEEERLPNAAAML 350


>UniRef50_A3MV77 Geranylgeranyl reductase n=5 Tax=Thermoproteaceae
           RepID=A3MV77_PYRCJ
          Length = 367

 Score =  161 bits (408), Expect = 3e-38,   Method: Composition-based stats.
 Identities = 65/291 (22%), Positives = 97/291 (33%), Gaps = 31/291 (10%)

Query: 4   FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           +DV ++G GPAGS  A           +  + Q       KPCGG L P  QR     G+
Sbjct: 12  YDVVVVGAGPAGSTAAIVAGRLGLKAVVVDRLQP---PREKPCGGGLTPRTQRLLNALGV 68

Query: 64  TLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLC 123
             PV    +  +                +   +   R  FD  +     + VE   D + 
Sbjct: 69  EYPVYGRCDTIVVQAAGYRYEMR-----REPILVTRRPDFDYALLK--QSGVEYVKDQVV 121

Query: 124 RKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAE 183
               R++          G         ++GADGA S V R +   +          +   
Sbjct: 122 E--VRDNTAV-------GRAGEYAGEVIIGADGATSAVARSIGVYNYKGHKSHGIAYMTI 172

Query: 184 KHPVPFYSCIFDNSI------TNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAF 237
               P   CI D            Y+W     G    G       G  ++  L+E ++ +
Sbjct: 173 ASGPPRDICIIDFDAVINTVGKVGYAWIFPLKGGANIGAG----TGWGKWLDLRELVAKY 228

Query: 238 QFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISY 288
               G   K  +      S       G+ N  L GEAAG + A++ EGI Y
Sbjct: 229 AESAGY--KPGQILGHPLSLGHVEGVGRGNVILAGEAAGLVDATTGEGIYY 277


>UniRef50_C6A374 Geranylgeranyl hydrogenase n=9 Tax=Thermococcaceae
           RepID=C6A374_THESM
          Length = 375

 Score =  161 bits (408), Expect = 3e-38,   Method: Composition-based stats.
 Identities = 64/335 (19%), Positives = 109/335 (32%), Gaps = 26/335 (7%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
            +DVAIIG GP G+ LA  LA + +V+ L+ K+  G     K C G++  +         
Sbjct: 6   RYDVAIIGGGPVGNYLANLLASEFKVVVLEAKNSFG----GKACTGIMGAENYEKL---- 57

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKS-LIPASVEVYHDS 121
             LP + I N    +V    + +            ++R   +  +    I    E Y  +
Sbjct: 58  -NLPKEAIINKLRGAVFYSRIQSFEIERPTPQAYVVDRKLLERKLAENAIRHGAEYYMGA 116

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWF 181
                         I +    +  I A + VGADG NS V + +            +   
Sbjct: 117 RFLGFK----NRKAIVQRFNEKFEIEADFYVGADGLNSKVAQEIGARTDAEFLSGYEVEV 172

Query: 182 AEKHPVPFYSCIFDNSI--TNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQF 239
                   +  I+ N       + W    + +    G +   D   RF            
Sbjct: 173 VGDFNRTDFVEIWVNKEINNEFFMWLAPINNFNARLGTFGTYDRLFRF--------LKLK 224

Query: 240 QFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSV 299
              +T   E         +      K N  L+G+AA  I   +  GI Y +  +  LR  
Sbjct: 225 LLKETNIVEIKAGNVGLGF-RKPWVKGNIALVGDAALQIKPLTAGGIVYGMLCSHALRYS 283

Query: 300 LLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTA 334
           + +   K+     +  +K       +I +      
Sbjct: 284 IRRGNLKMYEDLCKDIKKQI-SFGLRIRRLFKALN 317


>UniRef50_D2AYA7 Putative uncharacterized protein n=1 Tax=Streptosporangium roseum
           DSM 43021 RepID=D2AYA7_STRRD
          Length = 546

 Score =  161 bits (408), Expect = 4e-38,   Method: Composition-based stats.
 Identities = 60/382 (15%), Positives = 95/382 (24%), Gaps = 37/382 (9%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVI-ALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M   DV I+G GP G  LA  L  +      +++     T       G  L P +     
Sbjct: 1   MNSLDVLIVGAGPTGLTLACDLIRRGLTCRIVEQAPTPQTGSR----GFTLKPRSLEILD 56

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRN----------YQRSYININRHAFDLWMKS 109
             G    V   A  Q  +   +                      + + I +   +  M+ 
Sbjct: 57  DLGAAHRVLAAAQVQSRTRFHLGEPLLFDLRVPPAAPDPRRPHPNSLAIPQWRTEAIMRE 116

Query: 110 L-IPASVEVYHDSLCRKIWREDD-----KWHVIFRADGWEQHITARYLVGADGANSMVRR 163
                   V            D            R DG  + + A YLVGADG  S VRR
Sbjct: 117 RLAELGGVVEFGRRLTGFRSGDGQGEDAGVTATLRRDGVTETVRASYLVGADGGRSTVRR 176

Query: 164 HLYPDHQIRKYVAIQQ-----WFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGG-A 217
            L            +                                      +      
Sbjct: 177 RLGLAFSGSTDGDARALIADVHVDGPRHRDAVHLWMAADGHIVVLRPTPHAPTWQVVASL 236

Query: 218 YPMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGK----DNAFLIGE 273
            P  DG     +L+    A   + G+                +            FL G+
Sbjct: 237 APDTDGTWPEASLEHLQRAVTERTGRDDIRLSEPAWLSVWRYNLRMVDTYRVGRVFLAGD 296

Query: 274 AAGFISASSLEGISYALDSTDILRSVLL-----KQPEKLNTAYWRATRKLRLKLFGK-IV 327
           AA   S     G++  +     L   L         + L   Y      +   +  +   
Sbjct: 297 AAHVHSPFGGFGMNTGIQDAYNLGWKLALVLRGAAGDALLDTYQAERLPVARAILAESDR 356

Query: 328 KSRCLTAPALRKWIMRSGVAHI 349
           +    T P L + ++R  +   
Sbjct: 357 RFAAATPPRLIRPLLRFVLKPF 378


>UniRef50_Q2FUA4 Digeranylgeranylglycerophospholipid reductase n=5
           Tax=Methanomicrobiales RepID=GGR_METHJ
          Length = 402

 Score =  161 bits (407), Expect = 5e-38,   Method: Composition-based stats.
 Identities = 52/322 (16%), Positives = 85/322 (26%), Gaps = 22/322 (6%)

Query: 16  SALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQ 74
           +  A+  A     V+  +K+   G       C   +       F +         I    
Sbjct: 17  AFAAKTFAEKGYSVLLTEKRPAIGAPVR---CAEGVGKALMHEFFKPEDRWVAAEIEKAN 73

Query: 75  IFSVKTVDVAASLTRNYQRSYININRHAFDLWMK-SLIPASVEVYHDSLCRKIWREDDKW 133
           I +     +     +        ++R  FD  +      A  ++   +       ED   
Sbjct: 74  IIAPDGFKMELEPEKAGAEVGYVLHRKVFDRDLVWMAAGAGADIQVKTRAVTPIMEDGAV 133

Query: 134 -HVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKY---VAIQQWFAEKHPVPF 189
              I    G  Q + A   + ADG  S   R    D  +         Q           
Sbjct: 134 KGAILNQGGIAQEVRAGLTIAADGVESKFARWCGVDTTVPLREMETCAQYLMTGIDIDAH 193

Query: 190 YSCIFDN--SITNCYSWSISKDGYFI---FGGAYPMKDGQTRFTTLKEKMSAFQFQFGKT 244
            +  +         Y W   K         G          R      +  A  F  GKT
Sbjct: 194 ATEFYVGNNIAPGGYVWIFPKGDKTANVGIGVGGDRCKPGNRPIDYLNRFVARNFPNGKT 253

Query: 245 VKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLKQP 304
           ++                   +N  ++G+AA      +  GI  AL +  +   V  K  
Sbjct: 254 IEL--IAGGVSICQPLPCTVANNLMIVGDAARVSDPLTGGGIYAALYTGKLAGDVGSKAI 311

Query: 305 EKLNTA------YWRATRKLRL 320
           EK +T+      Y    R   L
Sbjct: 312 EKGDTSTQALMPYDETWRASYL 333


>UniRef50_B9LNF2 Geranylgeranyl reductase n=11 Tax=Halobacteriaceae
           RepID=B9LNF2_HALLT
          Length = 369

 Score =  160 bits (406), Expect = 6e-38,   Method: Composition-based stats.
 Identities = 63/342 (18%), Positives = 105/342 (30%), Gaps = 23/342 (6%)

Query: 5   DVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           D  ++G GP GS  AR+ A   + + + +K   GT      C G ++ D           
Sbjct: 3   DFVVVGAGPPGSRFARRAAAAGRDVVVFEKGSIGT---PLACSGHVSDDVWEYVPD---D 56

Query: 65  LPVDVIANPQIFSVKTVDVAASLTRNY---QRSYININRHAFDLWMKS-LIPASVEVYHD 120
              +++ N    +   V    S    +   +     I+R   D  +      A  +V  +
Sbjct: 57  ARDELLQNRVYGARFHVGGPGSKAYPFYKSEPVSNVIDRVGLDRTLADCAREAGADVREN 116

Query: 121 SLCRKIWREDDKWHVIFRA-DGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQ 179
                +   DD+  V  R   G  + + AR + G DG  S VRR L           +  
Sbjct: 117 HTVVGVDERDDRVVVEVRTPAGDVETVEARMVAGCDGPTSRVRRSLGLPEPDELLHGVLA 176

Query: 180 WFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQF 239
           +                +    ++W I +                     +         
Sbjct: 177 FDEAPDDGDLVDVHL--TAPTFFAWRIPRGD-----AGVEYGLAAPPSDDVSAMFDRLTD 229

Query: 240 QFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSV 299
            +  T     C+   P          D AFLIG+AA      +  GI Y + + D+   V
Sbjct: 230 AYDVTT-DHFCSGAIPVGPP-ERVTTDRAFLIGDAAAQTKPFTGGGILYGMTAADVAAEV 287

Query: 300 LLKQPEKLNTAYWRATRKLRL---KLFGKIVKSRCLTAPALR 338
           +  +       Y    R       +L   I +   L  P  R
Sbjct: 288 IDPRDPATLADYESGWRDAIGTEIRLGSAIRRCYSLPEPVQR 329


>UniRef50_UPI0001787E07 monooxygenase FAD-binding protein n=1 Tax=Geobacillus sp. Y412MC10
           RepID=UPI0001787E07
          Length = 383

 Score =  160 bits (406), Expect = 7e-38,   Method: Composition-based stats.
 Identities = 65/367 (17%), Positives = 122/367 (33%), Gaps = 43/367 (11%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD 61
           +  DV +IG G AG++ A +LA +     L  +    +    K CG  ++P+ +      
Sbjct: 3   KQADVMVIGAGVAGTSCALQLAKQGHRTILLDRQ---SFPRHKTCGEFMSPETREMLEYL 59

Query: 62  GLTLPV-DVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWM-KSLIPASVEVYH 119
           G+ L V +V       +   +     +T         I+R+  D  + +S + A  E+  
Sbjct: 60  GVHLQVQEVNPAAMDHASIVMPHGGVITAPLPGKATGISRYELDRLLHESAVSAGAEIVT 119

Query: 120 DSLCRKIW-REDDKWHVIFRADGWEQHITARYLVGADG---ANSMVRRHLYPDHQIRKYV 175
            S   +I  R D ++ +  R    +    AR ++GA G      +     Y D  +  YV
Sbjct: 120 GSAVTEIRKRGDHRYEIETRQGNEQIRYEARAVIGAYGTKKPRGVASAETYRDDTV--YV 177

Query: 176 AIQQWFAEKHPVPFYSCIFDNSITNCYSWSIS-KDGYFIFGGAYPMKDGQTRFTTLKEKM 234
            ++  FA           F       Y      ++G         +K  Q    ++ E +
Sbjct: 178 GVKSHFAGITVPSRVELYFCE---GGYVGISPVENGKVNVAALLTLKSVQGSGKSVPEIL 234

Query: 235 SA-------FQFQFGKTVKSEKCTV--------LFPSRWQDFVCGKDNAFLIGEAAGFIS 279
            A          +  +    E   V        + P  W  +         IG+A   + 
Sbjct: 235 KAASRSNNRLTERLAEGEPVEGTQVSIAPLRLSVRPEPWSQYPH-------IGDAMLMLP 287

Query: 280 ASSLEGISYALDSTDILRSVLLKQPEKL------NTAYWRATRKLRLKLFGKIVKSRCLT 333
               +G+S AL S+ +      K              Y     +   +L  +  + + L 
Sbjct: 288 PLCGDGMSVALRSSLLCSGWTDKYLNGEINFAQWQNHYTYEANRTFAQLLRRARRIQNLA 347

Query: 334 APALRKW 340
                ++
Sbjct: 348 FAKSNRF 354


>UniRef50_C5CID7 FAD dependent oxidoreductase n=1 Tax=Kosmotoga olearia TBF 19.5.1
           RepID=C5CID7_KOSOT
          Length = 377

 Score =  160 bits (405), Expect = 8e-38,   Method: Composition-based stats.
 Identities = 57/315 (18%), Positives = 104/315 (33%), Gaps = 23/315 (7%)

Query: 2   EHFDVAIIGLGPAGSALARKLAGK-MQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           +  +V IIG GPAGS  A  LA +   ++ +DK          K CGG+L   + +   +
Sbjct: 3   KKAEVIIIGAGPAGSTAATVLARRNFDILLIDK----CQFPRDKVCGGVLTAKSMKLLEK 58

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAA----SLTRNYQRS-YININRHAFDLWMKSLIPASV 115
               +   +   P                S+T  Y++  +    R   D  +      + 
Sbjct: 59  IHPGVVFSLNLKPITKVSFGYPGTERKNESITYIYKKPLFYVATRKELDNALMENALRNG 118

Query: 116 EVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYV 175
             Y +    +I R DD +    R+       +A Y+V A G        L    +I   +
Sbjct: 119 AKYENDAIIRIERLDDGFICHGRSGN---TYSAPYVVIAAGVFG--HNLLENTSKISYSI 173

Query: 176 AIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDG-QTRFTTLKEKM 234
           A +   A            D      Y+W +   G+F  G               + +K+
Sbjct: 174 AYKAQTASVPITTATINFHDF----GYTWILPGKGFFNVGIGSYDNSLTYADAENIVKKL 229

Query: 235 SAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTD 294
             F                      + V        +G++ GF+   + EGIS+A+++  
Sbjct: 230 FNFPIGKLNAAPLPMFDKTISVDLNNMVP---GCLFVGDSGGFVDPWTGEGISFAMETGF 286

Query: 295 ILRSVLLKQPEKLNT 309
                ++++      
Sbjct: 287 CSAKAIIEKGGDRLK 301


>UniRef50_C7DGR0 Geranylgeranyl reductase n=1 Tax=Candidatus Micrarchaeum
           acidiphilum ARMAN-2 RepID=C7DGR0_9EURY
          Length = 368

 Score =  159 bits (404), Expect = 1e-37,   Method: Composition-based stats.
 Identities = 65/340 (19%), Positives = 105/340 (30%), Gaps = 24/340 (7%)

Query: 1   MEH-FDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           ME  +D  I+G    G   AR+L+ K  V+ ++     GT      C G +   A   F 
Sbjct: 1   MEKRYDCVIVGGSITGLTAARELSKKASVLLVESNPAIGTPFR---CSGFINAPAFEEFA 57

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYH 119
                L    I N           +     + + S     R A +  +   I    ++  
Sbjct: 58  -----LDKSQIQNSISRLEVVHGGSRLTFASKKPSGFVTERPALERSLLGEIEPYTDIVA 112

Query: 120 DSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQ 179
                 I        V     G    ++A  L+GADG NS+VRR +       K  A+Q 
Sbjct: 113 GDRVVDIK----GATVSLHTSGN---VSAGCLIGADGTNSLVRRSIGIADP-EKVTAVQF 164

Query: 180 WFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQF 239
                      +          + W I  +      G     D +     L E +  ++ 
Sbjct: 165 ELPGSFESDCATIYVGEEFMPFHLWVIPVNESLARIGVGASGDVKAGMQRLLELVKKYKI 224

Query: 240 QFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRSV 299
                    +  V           G  +  L G + G I   SL GI + + S+ +    
Sbjct: 225 ADYPRYSESRFMVNTLPASPVSSTGTGSTMLAGMSGGIIKPLSLGGIYFGMLSSSMAARS 284

Query: 300 LLKQPEKLNTAYWRATR-----KLRLKLFGKIVKSRCLTA 334
           L+     L + Y R        +     F  + +   LT 
Sbjct: 285 LIDG--TLASGYRRKLENAGILRRVSDEFALLKRWSSLTD 322


>UniRef50_A4X5N9 Monooxygenase, FAD-binding n=3 Tax=Micromonosporaceae
           RepID=A4X5N9_SALTO
          Length = 442

 Score =  159 bits (404), Expect = 1e-37,   Method: Composition-based stats.
 Identities = 57/353 (16%), Positives = 107/353 (30%), Gaps = 37/353 (10%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           M  +D  +IG   +G++    LA +   + +  +    +          L P       R
Sbjct: 1   MPRYDAIVIGARCSGASTGMLLAQQGHRVLVVDRA---SFPSDVISTHFLWPHGTSYLNR 57

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQ-------------------RSYININRH 101
            G+   V +   P    V  V+    LT +                     RSY +I RH
Sbjct: 58  WGVLDQV-LAVTPAHTEVTFVNDGIPLTGSVPDELLRAYFRDWHGDDSGVVRSYASIRRH 116

Query: 102 AFDLWMKSLI-PASVEVYHDSLCRK-IWREDDKWHVIFRA-DGWEQHITARYLVGADGAN 158
             D  +      A  EV  +   ++ I   D    V  R  DG      AR +VGADG N
Sbjct: 117 VLDQILVEAASKAGAEVRTNFTVQELITEGDQVVGVRGRTSDGRLVEERARIVVGADGRN 176

Query: 159 SMVRRHLYPDHQIRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAY 218
           S V R L       +      +++                    + + +     +     
Sbjct: 177 SFVARSLGLPKFDERPRCTFAYWSYYSGFDLGPAQLHRRGRLACAVAPTNHDQNMVLVWG 236

Query: 219 P----MKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQD-----FVCGKDNAF 269
           P     +  +     L+  +     + G+ V+++           D              
Sbjct: 237 PSEWSREFRRDVPGNLQRALEFVSPELGEVVRAQGVRAERIYGTLDQSAFLRPLAGPGWV 296

Query: 270 LIGEAAGFISASSLEGISYALDSTDILRSVLLK--QPEKLNTAYWRATRKLRL 320
           L+G+A       +  G+++A    +++ + L +    +   +         R 
Sbjct: 297 LVGDAESAKDQCTAIGMTHAFRGAELVATALDRWLSGDASLSEAMATYEGRRR 349


>UniRef50_Q7USU8 Probable alkylhalidase homolog n=1 Tax=Rhodopirellula baltica
           RepID=Q7USU8_RHOBA
          Length = 374

 Score =  159 bits (404), Expect = 1e-37,   Method: Composition-based stats.
 Identities = 65/334 (19%), Positives = 109/334 (32%), Gaps = 25/334 (7%)

Query: 1   MEHF-DVAIIGLGPAGSALARKLAGKMQ-VIALDKKHQCGTEGFSKPCGGLLAPDAQRSF 58
           M  + DV +IG GPAG + A +L  +   V  ++K             G  LAP+A    
Sbjct: 1   MSQYSDVMVIGGGPAGCSTALRLRQQGATVTLIEKSDYSQQRP-----GESLAPEAIGFL 55

Query: 59  IRDGLTLPVDVIANPQ----IFSVKTVDVAASLTRNYQRS-YININRHAFDLWMKSLIP- 112
            + G+    D  A  Q    + S  +V ++ S           N++R  FD  +      
Sbjct: 56  NQLGVRDRFDAEAFQQTSGLLVSWGSVGISFSSFLTRPFGSGWNLDRARFDRMLSHACRQ 115

Query: 113 ASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDH-QI 171
           +SV+V       +     D+W +    D       +  +V A G  S +           
Sbjct: 116 SSVKVVFSRQSIQFVYSHDRWELQVGRD----SYRSPVIVDATGRASAMATRFGVQRIHD 171

Query: 172 RKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPM---KDGQTRFT 228
              +A+  +  E+   P    I        YS  +  D              K  + R T
Sbjct: 172 DHLIALVSYRDEQSCDPRL-VIESTPDGWWYSAGLPGDVSVTAFLTDVDLIPKRPEERTT 230

Query: 229 TLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKD---NAFLIGEAAGFISASSLEG 285
              E +   +F       S         R       +    + F +G+AA   S  S  G
Sbjct: 231 YFTELLEQTRFAHRGIAPSSPAFSPRLVRANTSRLSRPSSSHWFAVGDAAIATSPLSGNG 290

Query: 286 ISYALDSTDILRSVLLKQPEKLNTAYWRATRKLR 319
           I  AL++  +    ++      +  Y      +R
Sbjct: 291 IVRALETGLLAADAIVSTDTNASQRYNEVLASMR 324


>UniRef50_C3JMW7 Monooxygenase, FAD-binding protein n=2 Tax=Rhodococcus erythropolis
           RepID=C3JMW7_RHOER
          Length = 426

 Score =  159 bits (404), Expect = 1e-37,   Method: Composition-based stats.
 Identities = 61/351 (17%), Positives = 105/351 (29%), Gaps = 29/351 (8%)

Query: 2   EHFDVAIIGLGPAGSALAR-KLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           E +DV I+G   AG A A       +++  LD +           C   L P       R
Sbjct: 7   EKYDVVIVGASIAGCAAAIMYAQQGLRIALLDARSDIRAH--KVLCTHHLQPCGAPILQR 64

Query: 61  DGL---TLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPA--SV 115
            G     L + ++     F      +      N      N+ R   D  ++ L     +V
Sbjct: 65  LGATEKLLALGMVETVPTFWTPWGMITPDAAENSPPPGFNVRRETLDPLLRQLANDYPNV 124

Query: 116 EVYHDSLCRKIWREDDK-WHVIFRADGWEQHITARYLVGADGANSMVRRHLYPD--HQIR 172
           ++        +  E+     V     G    + AR  VGADG +S V R    D      
Sbjct: 125 DLLLGHRVSGLLTENGTTAGVYGTEQGSAFTVGARLTVGADGKDSTVARSARCDSVTASN 184

Query: 173 KYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLK- 231
              +     +        + +      +  ++ +  DG       +P  D    F     
Sbjct: 185 GRFSYFAQLSGLERPGGETSLSWFMDPD-VAYLLPNDGGISVLVVFPALDKLGSFADDLS 243

Query: 232 -EKMSAFQFQFGKTVKSEKCTVLFPSRWQDFV-----CGKDNAFLIGEAAGFISASSLEG 285
              +       G  +   +  V      + F         +   LIG+AA         G
Sbjct: 244 TAFLEYANALPGAPLVRREHIVGKIVGTKHFSTTLTEPVGNGFALIGDAAATNDPLWGIG 303

Query: 286 ISYALDSTDIL----RSVLLKQPEKLNTAYWR------ATRKLRLKLFGKI 326
            S+AL++  +L      +L + P     ++          R  R  +   I
Sbjct: 304 CSWALETAQMLVDATAHMLTETPADTLDSHRNVNAALTEYRSARASMTNHI 354


>UniRef50_B5I9Q2 FAD dependent oxidoreductase, putative n=2 Tax=Aciduliprofundum
           boonei T469 RepID=B5I9Q2_9EURY
          Length = 375

 Score =  159 bits (404), Expect = 1e-37,   Method: Composition-based stats.
 Identities = 62/344 (18%), Positives = 112/344 (32%), Gaps = 36/344 (10%)

Query: 4   FDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
           +DVAI+G GP GS + +++A     VI  ++  + G       C GL + +      + G
Sbjct: 2   YDVAIVGAGPIGSFIGKEIASLGYNVIIFEEHSEIGN---PSHCSGLFSTNIFDIVGKIG 58

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLI-PASVEVYHDS 121
           +  P           +   D +     N +     ++R  FD  +  +      E++   
Sbjct: 59  ILHPAKKAV------IYAPDGSKLRIGNDKVRGYVVDRVKFDRELAKMAGAKGAEIHLKE 112

Query: 122 LCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWF 181
             +K+   D            +    A+ +VGADG NS+VR+ +       K +   Q  
Sbjct: 113 RVKKVKYTD--------ISTSKGEYKAKIIVGADGINSIVRKEMGIGAP--KILGAAQII 162

Query: 182 AEKHPVPFYSCIFDNS--ITNCYSWSISK-DGYFIFGGAYPMKDGQTRFTTLKEKMSAFQ 238
           A  H       IF  S      ++W I   D     G A                +   +
Sbjct: 163 AHSHLDEDTVEIFIGSSIAPGFFAWRIPLFDDLAKIGLASYKSS----------WLYLKK 212

Query: 239 FQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDILRS 298
                 V+    +                  ++G+AAG + A+S  G+   L        
Sbjct: 213 LMKKLKVQPLSISGGGIPINTVERTYARGMLIVGDAAGQVKATSGGGVYPGLMCAKCAIK 272

Query: 299 VLLKQPEKLNTA--YWRATRKLRLKLFGKIVKSRCLTAPALRKW 340
            +    E+ + +    +          GK +K          K+
Sbjct: 273 AIKDALERGDYSENALKNYETCWRNGIGKELKYASYLHRLYTKF 316


>UniRef50_Q7UYT6 Probable alkylhalidase n=1 Tax=Rhodopirellula baltica
           RepID=Q7UYT6_RHOBA
          Length = 462

 Score =  159 bits (403), Expect = 1e-37,   Method: Composition-based stats.
 Identities = 48/323 (14%), Positives = 91/323 (28%), Gaps = 36/323 (11%)

Query: 23  AGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTVD 82
           A       L ++            G  L P+      R GL   V         SV+ V 
Sbjct: 55  ADSGVSTLLIERDPVPRFHV----GESLMPECYWPLERLGLIDQVKRSGWQAKKSVQFVT 110

Query: 83  VAASLTRNYQRS---------YININRHAFDLWMKSLIPA-SVEVYHDSLCRKIWREDD- 131
                +  +               + R  FD  +         + +  +    +  E   
Sbjct: 111 HTGKESAPFFFREHDERECSTTWQVERSEFDKMLYDRASELGADCFDQTRLIDVQTEPGE 170

Query: 132 -------KWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPD--HQIRKYVAIQQWFA 182
                  +  V+  ADG E+ I  + +V A G  + +   +     +   K  AI  ++ 
Sbjct: 171 TEDQPIARAVVVRTADGTEKTIGCKVVVDATGQQAFLAGKMGLKEINPDLKKAAIWTYYR 230

Query: 183 ----EKHPVPFYSCIFDNSITNCYSWSIS-KDGYFIFGGAYP-------MKDGQTRFTTL 230
                +      + I +    + + W I    G    G               +  F   
Sbjct: 231 DAVRGEGDNDGATIILNTKSRDSWFWFIPQSRGITSVGCVGDNDYLLKGRGTPEEIFEEE 290

Query: 231 KEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYAL 290
                  Q +     +  K T      +           LIG+A GFI      G+ +AL
Sbjct: 291 LANCPGLQPRLANATRVGKITTAKEFSYMTRRHSGPGWVLIGDALGFIDPVYSSGVYFAL 350

Query: 291 DSTDILRSVLLKQPEKLNTAYWR 313
           +        +++  +K + +  +
Sbjct: 351 EMGVRAGDAIVEGLKKDDLSAEQ 373


>UniRef50_A0B6Y7 Geranylgeranyl reductase n=1 Tax=Methanosaeta thermophila PT
           RepID=A0B6Y7_METTP
          Length = 381

 Score =  159 bits (403), Expect = 1e-37,   Method: Composition-based stats.
 Identities = 52/350 (14%), Positives = 115/350 (32%), Gaps = 26/350 (7%)

Query: 6   VAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDA-QRSFIRDGL 63
           + ++G GPAGS  A   A     VI ++++ + G+      CGG +   +  R  + D +
Sbjct: 3   IIVVGAGPAGSTAAETAARLGADVILVERRMEIGS---PVQCGGFIPEASELRDLLPDAV 59

Query: 64  TLPVDVIANPQ----IFSVKTVDVAASLTRNYQRSYININRHAFDLWMKS-LIPASVEVY 118
                V    +       ++ +   +  +  +  +   ++R +FD ++      A  ++ 
Sbjct: 60  LPETLVEIPERCILNRTRIQRLYAPSGRSAEFPVAGRCVDRRSFDRYLAHRAARAGAQLI 119

Query: 119 HDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQ 178
             +         +  H+  R +G           G    +S +   +    +    + ++
Sbjct: 120 VGTEA---DVRGESIHLKGRREGIIDADIIIGADG---PSSRIAEAIGAVQRDEPGICLE 173

Query: 179 QWFAEKHPVPFYSCIFDNS--ITNCYSWSIS-KDGYFIFGGAYPMK--DGQTRFTTLKEK 233
               +       + ++         Y+W I   D     G         G+     +  +
Sbjct: 174 YEMVDVDIDRDAAEMYFGERWAPGGYAWIIPLGDDIANVGVGVRRSYIRGEIDLPLILRR 233

Query: 234 MSAFQFQFGKTVKSEKC----TVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYA 289
                   G+ ++  +       + PS     +       L G+AAG + A+S  G+  A
Sbjct: 234 FVEEHPHAGRILRKGEIVAVMRGIVPSGGMPEIIQSGRFLLAGDAAGHVMATSGGGVPLA 293

Query: 290 LDSTDILRSVLLKQPEKLNTA-YWRATRKLRLKLFGKIVKSRCLTAPALR 338
           + +  I   V        +   Y +   K         V  R +   A+R
Sbjct: 294 MVAGRIAGEVAATHARGGDLNVYTQRIEKELGAPLRGSVIIRRMVDRAMR 343


>UniRef50_P26484 Protein fixC n=50 Tax=Bacteria RepID=FIXC_AZOC5
          Length = 435

 Score =  159 bits (403), Expect = 1e-37,   Method: Composition-based stats.
 Identities = 59/334 (17%), Positives = 112/334 (33%), Gaps = 36/334 (10%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           E FD  ++G G AG+A    LA   ++V+ L++    G++      G +L  D     + 
Sbjct: 4   EKFDAIVVGAGMAGNAATLTLARRGLKVLQLERGEYSGSKN---VQGAILYADMLEKLVP 60

Query: 61  DG-LTLPVDVIANPQIF------SVKTVDVAASLTRNYQRSYININRHAFDLWMKSLI-P 112
           D     P++     Q F      S   +   +      + +   I R  FD W  S +  
Sbjct: 61  DFREDAPLERHLVEQRFWMLDDRSHVGLHYRSEDFNEEKPNRYTIIRAQFDKWFSSKVKE 120

Query: 113 ASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLY-PDHQI 171
           A   V  ++   ++ ++     +  + D     I A  +V A+G N ++    +  +   
Sbjct: 121 AGATVLCETTVTELVQDAYGKVIGVKTDRSGGQIHADVVVLAEGVNGLLGTKAHLRERPK 180

Query: 172 RKYVAIQQWFAEKHPVPFYSCIFD------------NSITNCY---SWSISKDGYFIFGG 216
            ++VA+        P       F+             +I+       +  +       G 
Sbjct: 181 PEHVALAVKEMHFLPRETIEARFNLQGDEGVVIEAAGTISRGMTGMGFIYANKECISLGI 240

Query: 217 AYPMKDGQTRFTTLKEKMSAFQFQFG------KTVKSEKCTVLFPSRW--QDFVCGKDNA 268
              + D Q    T    +  F+           +   E    L P            D  
Sbjct: 241 GCLVSDFQKTGETPYGLLERFKSHPSVAPLIEGSEVKEYAAHLIPEGGFKAIPQLFGDGW 300

Query: 269 FLIGEAAGFISASSLEGISYALDSTDILRSVLLK 302
            ++G+AA   +A   EG + A+ S  I    + +
Sbjct: 301 VVVGDAAQLNNAVHREGSNLAMTSGRIAAEAIFQ 334


>UniRef50_C6XP81 Monooxygenase FAD-binding n=1 Tax=Hirschia baltica ATCC 49814
           RepID=C6XP81_HIRBI
          Length = 492

 Score =  159 bits (402), Expect = 2e-37,   Method: Composition-based stats.
 Identities = 57/343 (16%), Positives = 111/343 (32%), Gaps = 31/343 (9%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
             +DV +IG GP G  LA  LA   ++ + LDK+     + +  P    +  +  R F  
Sbjct: 5   NEYDVIVIGAGPTGMTLALFLAQNGVKTLVLDKEE----DVYPLPRAAHIDHEIMRIFQD 60

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYI---------NINRHAFDLWMKSLI 111
            G+   V+                  L +      I          I++ + +  ++   
Sbjct: 61  LGVADVVESTCRSSKTYDFVTGDGRMLMQFDGLDAIGPGGWPVGNMIHQPSIERILRDAA 120

Query: 112 PASV--EVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDH 169
             +   +++ +      +  D    V+ ++      ++A +LVGADGA S VRR    + 
Sbjct: 121 SKNSNLDLWTNCEFEAFFENDSGVAVVLKSGEKSVRLSASFLVGADGARSSVRRQAGIEQ 180

Query: 170 QI----RKYVAIQQWFAEKHPVPFYSC-IFDNSITNCYSWSISKDGYFIFGGAYPMKDGQ 224
           +       ++ +     +   +P  +  I D           S    + F       D  
Sbjct: 181 EDLNFDEPWLVVDAIVHDFDRLPKVNLQICDPERPTSCVLMGSGRHRWEF---MLKPDEV 237

Query: 225 TRFTTLKEKMSAFQFQFG--KTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASS 282
                    ++     +G    V+ E+  V   +        K   FL G+AA      +
Sbjct: 238 PEEMARDSVVAGLLEPWGVEGAVEIERTAVYRFNAKVAKSWRKARVFLAGDAAHLTPPFA 297

Query: 283 LEGISYALDSTDILRSVLLK-----QPEKLNTAYWRATRKLRL 320
            +G+   +     L   L++       + L   Y         
Sbjct: 298 GQGMCAGIRDAANLAWKLVQFLKFGASDGLLETYQNERDAHAR 340


>UniRef50_B1MM05 Putative FAD-binding monooxygenase n=1 Tax=Mycobacterium abscessus
           ATCC 19977 RepID=B1MM05_MYCA9
          Length = 475

 Score =  159 bits (402), Expect = 2e-37,   Method: Composition-based stats.
 Identities = 58/349 (16%), Positives = 108/349 (30%), Gaps = 35/349 (10%)

Query: 6   VAIIGLGPAGSALARKLAGKMQVI-ALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLT 64
           V I G GP G  LA +L  +      LDK          K     L+P  Q  F   G+ 
Sbjct: 3   VVIAGAGPTGLTLACELTRRGIACRVLDKAPDLFPGSRGK----GLSPRTQEVFDDLGIA 58

Query: 65  LPV----------------DVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMK 108
             +                +V+A   +  +   D+ +     Y   +  + +   D  + 
Sbjct: 59  PAINSGGMAMPPFRIYAGHEVVAERSLVEMLGTDIPSGPGIPYP-GFWLVPQWRTDEILL 117

Query: 109 SLIPA-SVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYP 167
             +     +V  +       +  D   V+    G  + + A YLVGADG  S VR+ L  
Sbjct: 118 DRLRQFGGDVEFNCEVVGFTQRSDAVSVMVSQGGAPELLHASYLVGADGGRSTVRKMLGV 177

Query: 168 DHQIRKYVAIQQWFAEKHPVPFYSCIFDNSITNC------YSWSISKDGYFIFGGAYPMK 221
                 +   +    +                +         W++    ++ F      +
Sbjct: 178 GFAGETFERERTLIGDVRADGLEGSFCHVLTRDGQVSERFSLWNLPGSEHYQFVANMATE 237

Query: 222 DGQTRFTTLKEKMSAFQFQFGKTV--KSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFIS 279
           D         +K+   +      V       ++   +             L G+AA   S
Sbjct: 238 DVPALTLDAVQKLVVDRSGRDDIVLRDLRWISLYRVNARMVDRFRVGRVILAGDAAHVHS 297

Query: 280 ASSLEGISYALDSTDI----LRSVLLKQPEKLNTAYWRATRKLRLKLFG 324
           ++  +G++ ++         L +V+   PEKL   Y      +   + G
Sbjct: 298 SAGGQGLNTSVQDAYNLGWKLAAVIYGAPEKLLDTYEEERMPVAASVLG 346


>UniRef50_A0B730 Geranylgeranyl reductase n=1 Tax=Methanosaeta thermophila PT
           RepID=A0B730_METTP
          Length = 386

 Score =  159 bits (402), Expect = 2e-37,   Method: Composition-based stats.
 Identities = 57/344 (16%), Positives = 104/344 (30%), Gaps = 21/344 (6%)

Query: 1   MEHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M+ +DVA+IG GPAG   A+  +    + I L++    G   +   C GLL   A  +  
Sbjct: 1   MDIYDVAVIGAGPAGLMAAKHASMCGARTIVLEEHMAIG---YPVQCAGLLGISALEASE 57

Query: 60  RDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRS-YININRHAFDLWMK-SLIPASVEV 117
                     + NP   +V      + L+          ++R  FD  M  + +   VE+
Sbjct: 58  IQTEG----FLINPFKGAVFVSPNGSRLSFKSPNVRAWAVDRRLFDRSMALAAVHHGVEI 113

Query: 118 YHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAI 177
             ++  R + R  D   +       ++ I AR ++ A+G  + + R        R     
Sbjct: 114 TLNAHVRSLRRLGDLMILHH----GDKEIAARAVISAEGVRASIARRSGIPPPKRLLSGA 169

Query: 178 QQWFAEKHPVPFYSCIFDNSI--TNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMS 235
           Q              +          ++W I         G    +              
Sbjct: 170 QVEVPFDVDDIESVEVHLGKDIAPGLFAWVIPISRSSARIGLCATERACHYLKKFLSSDR 229

Query: 236 AFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSTDI 295
                 G  V         P    D     D   ++G+AA  +  +S  G+   +    I
Sbjct: 230 IRNRILGSPVAL--VVGGLPLGPPDRT-VADGLLVVGDAAAHVKPTSGGGVYPGIVCGRI 286

Query: 296 LRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRK 339
              +  +              +      G+ +         LR+
Sbjct: 287 AGRIAAEHVLTGGQ--LERYEREWRSAIGREISLGMRVNDILRR 328


>UniRef50_C6WHE7 Monooxygenase FAD-binding n=2 Tax=Actinomycetales
           RepID=C6WHE7_ACTMD
          Length = 429

 Score =  158 bits (401), Expect = 2e-37,   Method: Composition-based stats.
 Identities = 57/342 (16%), Positives = 102/342 (29%), Gaps = 22/342 (6%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
            +DV ++G   AG A A + +     +AL  +         + C   + P A       G
Sbjct: 21  SWDVVVVGGSIAGCATAIRFSRMGHRVALLDRKTMDDGHHKRLCTHFIQPHAVPLLAGLG 80

Query: 63  LTLPVDVIANPQIFSVKTVDVAASLTRNYQRS-------YININRHAFDLWMKSLIPA-S 114
           L        + +  +V                        +N+ R   D  ++       
Sbjct: 81  LDHLYGPEWSVRTKAVFVTPGGVVEGPGLSYDPDQPGAHALNLERRVLDPALRESARRHG 140

Query: 115 VEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRK- 173
           VE    +    I R+   W +    D   +   AR +V ADG  S + + L    + R  
Sbjct: 141 VEYLDGTGVESIGRDGSDWFLDTDGDRGPRRFRARLVVAADGRRSRLAKELGNPAESRPN 200

Query: 174 -YVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKE 232
              A+  +F+          +F     +  + +    G       +  K     +     
Sbjct: 201 ERAALFGYFSGITTRADQRSVFVMHERD-LACAYPLPGGRTQLVLFADKARVEGWGGADN 259

Query: 233 KMSAFQFQFGKTVKSEKCTVLFPSRW---------QDFVCGKDNAFLIGEAAGFISASSL 283
           +M  F   F     +       P                   D+   +G+AA  +   S 
Sbjct: 260 RMREFLAYFDGLPDAPSTAGAVPEGGLLGYADYPSLLREPVVDSVPFVGDAALSLDPMSG 319

Query: 284 EGISYALDSTDILRSVLLKQ--PEKLNTAYWRATRKLRLKLF 323
            G  +AL S D+L S    +   E    A     R+   ++ 
Sbjct: 320 VGCGFALVSADLLASSFADRSLSEDDREAGLAEYRERYSRVL 361


>UniRef50_Q08YP8 Monooxygenase family protein n=1 Tax=Stigmatella aurantiaca DW4/3-1
           RepID=Q08YP8_STIAU
          Length = 451

 Score =  158 bits (401), Expect = 2e-37,   Method: Composition-based stats.
 Identities = 63/359 (17%), Positives = 119/359 (33%), Gaps = 20/359 (5%)

Query: 7   AIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLP 66
            IIG GPAG A A  L+     + L    Q  ++   +  G LL P         G    
Sbjct: 2   VIIGAGPAGCASAAALSQLGHSVLLIDAGQDRSK---QLAGELLHPPGVEDLRTLGFGPA 58

Query: 67  VDVIANPQIFSVKTVDVAAS-----LTRNYQRSYININRHAFDLWMKSLIPA--SVEVYH 119
           ++      +     VD         LT N     +++    F   +   +    +V V+ 
Sbjct: 59  LEACHGQPVQGFAVVDTRRERRTTQLTYNGSSQGLSLEHARFAQSLLEAVERLPNVTVWR 118

Query: 120 DSLCRKIWRED-DKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQ 178
            +    + R D D   +     G +Q +    LV ADG +S VR+ L  + Q  +  ++ 
Sbjct: 119 KTRLTALLRNDADGVVLTVVRGGEQQQVFTPLLVAADGRSSFVRKLLGIEEQHDRLSSMV 178

Query: 179 QWFAEKHPVPF--YSCIFDNSITNCYSWSISKDGYFI---FGGAYPMKDGQTRFTTLKEK 233
               +   +P   +  IF        +++I  D   +          +   +    L   
Sbjct: 179 GVTVDAQALPHAGHGHIFIGGNAPVLAYAIEPDVARVMVDVPLGATAQQLHSSPELLNGV 238

Query: 234 MSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDST 293
               +    + ++ E   +                 L+G+AAG     S  G++  +   
Sbjct: 239 PQPLRGAILEALERETPRMASNDTRLPRRVTLGRVVLVGDAAGCCHPVSASGMASGISDA 298

Query: 294 DILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKW----IMRSGVAH 348
             L+  L +    +  A  R  ++ R     +I  +  L      +      +R+G+  
Sbjct: 299 MALQQSLRESLNNVPRALRRYVQRRRSAQRTRIALASALYQAFSIQREDMDALRTGLLR 357


>UniRef50_A8MAE2 Geranylgeranyl reductase n=6 Tax=Thermoproteaceae
           RepID=A8MAE2_CALMQ
          Length = 459

 Score =  158 bits (401), Expect = 2e-37,   Method: Composition-based stats.
 Identities = 53/345 (15%), Positives = 107/345 (31%), Gaps = 45/345 (13%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           + +DV I+G G AGS  A  +A   + V  +++K         K  G  +         +
Sbjct: 3   KTYDVLIVGAGTAGSYAAYLMAKQGLSVALVERKRAEEVF---KVTGDAIGKHHIEELTK 59

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLI-PASVEVYH 119
            GL++  DV       +        S+          ++   +  W+ +    +  ++  
Sbjct: 60  SGLSISNDVFMIKYEGAELYSP-DLSIKYFVAGEGYGLDIGKWAQWLINAANNSGADIID 118

Query: 120 DSLCRKIWREDDKWHVI--FRADGWEQHITARYLVGADGANSMVRRHL-------YPDHQ 170
           +        E      +   R DG +  + A+  V A GA  +VR  L        P   
Sbjct: 119 NHTVSTPIIEGGFVKGVKASRRDGTQVELRAKVTVDASGATGVVRTKLPSQYRISEPLLP 178

Query: 171 IRKYVAIQQWFAEKHPVPF----YSCIFDNSITNCYSWSISKDGYF-IFGGA----YPMK 221
                A ++     + +P        + +N     Y W   K       G         +
Sbjct: 179 EDASYAYREIVEVDYSIPNPQNIRIYLDNNISPGGYWWFFPKSDRVANVGLGIWGRLVKE 238

Query: 222 DGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFI--- 278
           +G       ++ +++  +  G+ +       + P+R                    I   
Sbjct: 239 NGLNPRINYEKYLASSPYVKGRKL-LHTGGGIVPTRRPLASMVGPG----------IVAV 287

Query: 279 -------SASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATR 316
                  +     GI  AL S+ +    +++  EK + +     R
Sbjct: 288 GDAAVAVNPIHGGGIGPALLSSALASKAIIEALEKGDVSEAGLWR 332


>UniRef50_A8M0H4 Tryptophan halogenase n=130 Tax=Bacteria RepID=A8M0H4_SALAI
          Length = 507

 Score =  158 bits (400), Expect = 3e-37,   Method: Composition-based stats.
 Identities = 57/321 (17%), Positives = 97/321 (30%), Gaps = 36/321 (11%)

Query: 13  PAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRD-GLTLPVDVIA 71
           PAGS  A  +A +   + L ++ +          G  L P       R  G    ++  A
Sbjct: 30  PAGSTAATLVAMQGHRVLLLERERFPRY----QIGESLLPSTVHGICRLIGADEALERAA 85

Query: 72  NPQIFSVKTVDVAASLTRNYQRS-----------YININRHAFDLWMKSLIP-ASVEVYH 119
                       A      +                 + R  FD  +        VEV  
Sbjct: 86  FTIKRGGTFRWGANPQPWTFSFGISPRFAGEAATAYQVERMKFDQILLDNARSRGVEVRE 145

Query: 120 DSLCRKIWREDDKWHVIFRAD--GWEQHITARYLVGADGANSMVRRHLYPDHQIRKY--V 175
           +   R +  E  +   +  AD  G E+ + A Y+V A G  S +R H    H  + +  +
Sbjct: 146 ECDVRDVVAEHGRVVGVRYADASGHEREVRAAYVVDASGHASRLRAHAGTRHYSKFFRNL 205

Query: 176 AIQQWFAE--KHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAYPMK--------DGQT 225
           A+  +F    + P P    I   +  + + W I         GA  +         D + 
Sbjct: 206 ALFGYFTGGKRLPPPNEGNILAAAFDSGWFWYIPLGPELTSVGAVLLPEALDRIQGDRER 265

Query: 226 RFTTLKEKMSAFQFQFGKTVKS-----EKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISA 280
               L E+      Q     +       +  +     +      +    L G+AA FI  
Sbjct: 266 ALLDLIEECPLIAEQLADAERVRTGPYGEIRIRKDYSYLQDRFWRPGLVLAGDAACFIDP 325

Query: 281 SSLEGISYALDSTDILRSVLL 301
               G+  A  S  +    + 
Sbjct: 326 VFSSGVHLATYSAMMAARSIN 346


>UniRef50_O07561 Uncharacterized aromatic compound monooxygenase yhjG n=5
           Tax=Bacillus subtilis group RepID=YHJG_BACSU
          Length = 499

 Score =  158 bits (400), Expect = 3e-37,   Method: Composition-based stats.
 Identities = 53/341 (15%), Positives = 103/341 (30%), Gaps = 17/341 (4%)

Query: 1   MEHFDVAIIGLGPAGSALARKLA-GKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFI 59
           M  ++  IIG GP G  LA +LA   +    +++  +      SK     L P       
Sbjct: 2   MMKYEAVIIGGGPVGFMLASELAIAGVGTCVIERLEKP--VPHSKALT--LHPRTLELLE 57

Query: 60  RDGLTLPVDVIANPQ---IFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPA-SV 115
             G+        +      FS+    +  S         + + +   +  ++    +   
Sbjct: 58  MRGILERFVSKGSKIPTGHFSMLDTRLDFSGLDTSCPYTLLLPQSKTEKLLEDHARSLGT 117

Query: 116 EVYHDSLCRKIWREDDKWHVIFR-ADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKY 174
           EV+  +    + +  +    IF+  DG  + IT+++ VGADGA S VR+    +      
Sbjct: 118 EVFRGAEALAVTQNGEAVQTIFKDRDGSVRTITSKFAVGADGAGSTVRKQAKIEFPGTDS 177

Query: 175 VAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKD-GYFIFGGAYPMK-----DGQTRFT 228
                        P  S +            +      +      P +     D      
Sbjct: 178 TVTAALGDVVLLSPPPSGVLSLCTKEGGVMIVPLSPDRYRVVVISPYRTQTPKDVPVTEE 237

Query: 229 TLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISY 288
            LK  +                +    +  Q         FL G+AA     +  +G++ 
Sbjct: 238 ELKADLLRICGTDFGLTDPSWMSRFGNAARQAKRYRDGRIFLAGDAAHIHFPAGGQGLNV 297

Query: 289 ALDSTDILRSVLLKQPEKLNTAY-WRATRKLRLKLFGKIVK 328
            L     L   L    +    ++   +    R      +++
Sbjct: 298 GLQDAMNLGWKLAAAIKGSAPSWLLDSYHDERHPAAEGLLR 338


>UniRef50_Q30ZB0 Geranylgeranyl reductase n=1 Tax=Desulfovibrio desulfuricans subsp.
           desulfuricans str. G20 RepID=Q30ZB0_DESDG
          Length = 383

 Score =  158 bits (400), Expect = 3e-37,   Method: Composition-based stats.
 Identities = 56/365 (15%), Positives = 108/365 (29%), Gaps = 44/365 (12%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDG 62
            +D  ++G GP G++ A  LA     + +      G     K CGGLL   +        
Sbjct: 8   RYDAVVVGGGPCGASAAFTLARNGYTVMVID---AGKFPRFKLCGGLLTGKSTAFLRDCF 64

Query: 63  LTLPVDVIANPQIFS-----VKTVDVAASLTRNYQRSYININRHAFD-LWMKSLIPASVE 116
                 +     +                +  +    +  + R  FD   +KS+  A   
Sbjct: 65  GMDASCLARAGALEGCENSYHIYAGGRRIVAGSNGSPFYFVRRDRFDSRLLKSVAAAGAV 124

Query: 117 VYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHL--YPDHQIRKY 174
           V   +          K H           + A +++ ADG +S VR+ +     H +R+ 
Sbjct: 125 VREGTKVVHADCRTGKVHCH-----DGSSVCAEFIIAADGVHSTVRKAVCGGLRHSVRQA 179

Query: 175 VAIQQWFAEKHPVPFY--SCIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKE 232
           VA++     +H         +    +   Y W        + G    +  G+     L+ 
Sbjct: 180 VAVEVAVPRRHMPQGVQLPSVHLGLLQRGYGWLFPNRRNIVAGVGGLLCRGEHPARVLRT 239

Query: 233 KMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFL----------IGEAAGFISASS 282
            +     Q G   +        P              L          +           
Sbjct: 240 LLCGCGVQAGHIPQPRGY--TLPFGGHLRRPFSGRVLLAGDAAGFADAV----------F 287

Query: 283 LEGISYALDSTDILRSVLLKQ-PEKLNTAYWRATRKL---RLKLFGKIVKSRCLTAPALR 338
            EGI YA+ S  +    +++  P +   +            ++L  + +      A  L 
Sbjct: 288 GEGIYYAMLSGSLAAQAVMQALPVRAAGSVLHEEHGAGTFYMQLLQRNLFRTLGQAAVLH 347

Query: 339 KWIMR 343
           +++ R
Sbjct: 348 RFLYR 352


>UniRef50_Q1AWH0 Geranylgeranyl reductase n=1 Tax=Rubrobacter xylanophilus DSM 9941
           RepID=Q1AWH0_RUBXD
          Length = 420

 Score =  158 bits (399), Expect = 4e-37,   Method: Composition-based stats.
 Identities = 58/317 (18%), Positives = 96/317 (30%), Gaps = 31/317 (9%)

Query: 2   EHFDVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIR 60
           E +D+ ++G GP GS+ A   A   ++ + LD++    +    KPCG  L P A      
Sbjct: 3   ERYDLIVVGAGPGGSSTAYHAARSGLKTLLLDRQ----SFPRDKPCGDGLMPHAAAELAL 58

Query: 61  DGLTLPVDVIANPQIFSVKTVDVAASLTRNYQR-----SYININRHAFDLWMKSLIPASV 115
            GL   ++   +            A L +               R   D  +      + 
Sbjct: 59  MGLGGWLEEEHHGAFTGFTIYSETAVLRQKVPPTLHGPRGYVARRKETDARLAGRAAEAG 118

Query: 116 E-VYHDSLCRKIWREDDKW--HVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIR 172
             +   +   ++ R        V     G      A  +V ADG               +
Sbjct: 119 AELMEQTRAARLLRSAAGTVSGVEAERSGERVRFAAPLVVVADGVGGF---AAGGMKARQ 175

Query: 173 KYVAIQQWFAEKHPVPFYSCIFD-----NSITNCYSWSIS-KDGYFIFGGAYPMKDGQTR 226
             VA +Q+F                   NS    Y W     DG    G     +  +  
Sbjct: 176 NAVARRQYFRGVSGPEREHLQIFITPDMNSHHAGYGWVFHFGDGTANVGAGVSTRALERS 235

Query: 227 FTTLKEKMSAFQFQFGKTVKSEKCTVLFPSR--------WQDFVCGKDNAFLIGEAAGFI 278
              LK+    F  +     +        P +        W      +    L+G+A   +
Sbjct: 236 GRNLKDFYDRFLEEPRVREQLAGAEPEGPPKSWSLKMGMWGARRYAQG-TMLVGDAGSMV 294

Query: 279 SASSLEGISYALDSTDI 295
              S EG+ YAL+S  +
Sbjct: 295 HPISGEGVGYALESGRL 311


>UniRef50_B7RS31 FAD binding domain protein n=1 Tax=Roseobacter sp. GAI101
           RepID=B7RS31_9RHOB
          Length = 413

 Score =  158 bits (399), Expect = 4e-37,   Method: Composition-based stats.
 Identities = 50/335 (14%), Positives = 100/335 (29%), Gaps = 42/335 (12%)

Query: 5   DVAIIGLGPAGSALARKLAG-KMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGL 63
           D A+IG GP+G   A  LA     V+ L++             G  + PD  +     G 
Sbjct: 7   DFAVIGTGPSGCMSAGLLAKAGFDVVMLERDVHPRN-----TVGENMIPDFWKFTDMIGA 61

Query: 64  TLPVDVIANPQIFSVKTVDVAASLT-----RNYQRSYININRHAFDLWM-KSLIPASVEV 117
           +  +           +                Y+R  ++++R  FD  + +        +
Sbjct: 62  SEDIKKAGFVTKRGGRVHWDGQVERLAFRDFGYERPGLHVDRDEFDSILVRHAQRLGARL 121

Query: 118 YHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLY--PDHQIRKYV 175
           + +   RK+   +++  V +        I+ RY++ A G   ++ R L     +   +++
Sbjct: 122 FENVTVRKVDFGEERQSVRYDTADGPGQISVRYVIDASGQGGLLARQLGTRVTNPDFRFM 181

Query: 176 AIQQWFAEKHPVPFYSCIFDNS-----------------ITNCYSWSISKDGYFIFGGAY 218
           A   +F       +    + +S                     ++W I        G   
Sbjct: 182 AFWGYFENSRYYDYDGVSYPHSMIQDVPCVTTQVSLTEGDHIGWAWHIPLRKSTSVGCVL 241

Query: 219 PMKDGQTRFTTLKEKMSAFQFQFGK-----------TVKSEKCTVLFPSRWQDFVCGKDN 267
             +               F+   G            T+   K   +              
Sbjct: 242 LRETVVKLKQNFDNWEDRFEHLVGNEPVLQHLLENATLIDRKFHFINNFSGHSAQIAGPG 301

Query: 268 AFLIGEAAGFISASSLEGISYALDSTDILRSVLLK 302
            F +G+AAGF       G++  L S  +      +
Sbjct: 302 FFQVGDAAGFFDPIFSIGVTLGLYSGSLAAWFAAE 336


>UniRef50_Q1QK25 Monooxygenase, FAD-binding n=2 Tax=Nitrobacter RepID=Q1QK25_NITHX
          Length = 401

 Score =  157 bits (398), Expect = 5e-37,   Method: Composition-based stats.
 Identities = 65/376 (17%), Positives = 115/376 (30%), Gaps = 43/376 (11%)

Query: 3   HFDVAIIGLGPAGSALARKLAGKM-QVIALDKKHQCGTEGFSKPCGGLLAPDAQRSF--- 58
            +DV I+G GPAG+A A  LA    +V+ ++K+         K  G  L P +       
Sbjct: 13  TWDVVIVGSGPAGAATAITLARYGQRVLLVEKRGS----PRFKL-GESLPPTSIGLVKHF 67

Query: 59  --IRDGLTLPVDVIANPQIFSVKTVDVAASLTRNY---QRSYININRHAFDLWMK-SLIP 112
               DG    +  + N            A +T  +       + ++R AFD  ++ + + 
Sbjct: 68  LADPDGPEQQLPGLFNTAGNVSLWATGQADITDFFFTSTGHGLCVDRLAFDEALRTTAVA 127

Query: 113 ASVEVYHDSLCRKIWREDDK---WHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDH 169
           A   +      +   R  D    W +   +    +   ARYLV   G  ++V R L    
Sbjct: 128 AGATLLRGVGFQSCARIADGSFNWQLTLSSGAGTRQHRARYLVDCSGRPAVVARSLGVPT 187

Query: 170 --QIRKYVAIQQWFAEK-HPVPFYSCIFDNSITNCYSWSIS---KDGYFIFGGAYPMKDG 223
                +  A  QWF+        Y+ I        YS  +              +  KD 
Sbjct: 188 VPNDDRLFAYAQWFSCTSADDDRYTRIEAAPHGWWYSNRLPSTEGSETRRLVVWHTDKDL 247

Query: 224 Q-TRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSR---------WQDFVCGKDNAFLIGE 273
              +    ++                +     P            +      D    +G+
Sbjct: 248 PAAKMAAYRQGFEQLLDDSTHIAPLLRARGYHPCGTIRGAPANSQRLRDFCGDAWMAVGD 307

Query: 274 AAGFISASSLEGISYALDSTDILRSVL---------LKQPEKLNTAYWRATRKLRLKLFG 324
           AA      S +GI  AL +      ++                  AY +   + + +L+ 
Sbjct: 308 AAQAYDPLSSQGIDKALRTASHAGHMIHYALTDCPQGGAGLDSRNAYVQQYDEQQRQLWQ 367

Query: 325 KIVKSRCLTAPALRKW 340
             +  R        +W
Sbjct: 368 AYLSQRDYYYGIQPRW 383


>UniRef50_C5V9R0 FAD-linked oxidoreductase n=2 Tax=Corynebacterium matruchotii
           RepID=C5V9R0_9CORY
          Length = 463

 Score =  157 bits (398), Expect = 5e-37,   Method: Composition-based stats.
 Identities = 54/360 (15%), Positives = 94/360 (26%), Gaps = 52/360 (14%)

Query: 20  RKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVK 79
                +     L            K CG  L P A       GL     V+A  +   +K
Sbjct: 34  IHAGRRGISTLLIDAQ---PFPRDKTCGDGLTPRAIHQLQLLGL--ADSVVARYRSHGLK 88

Query: 80  TVDVAASLTRNYQRSYIN-----INRHAFDLWMKSLIPAS--VEVYHDSLCRKI------ 126
                 S+T  +  S        + R  FD ++     +   VE         +      
Sbjct: 89  LHGFGGSVTAPWPESAFGTVGSAMPRREFDDFLVGCARSHPSVEFLGGVRAVAVSMSTPV 148

Query: 127 ----------------WREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQ 170
                                   V          +  + ++ ADG  S + + L     
Sbjct: 149 GAGSDSIISGSGIMSGDAASVGALVAAVELSDGSWVRPKQVIVADGVRSPIGKLLGRTWH 208

Query: 171 IRKYVAIQQWFAEKHPVPFYSCIF--------DNSITNCYSWSIS-KDGYFIFGGAYPMK 221
             +   I        P      I         D      Y W     +G    G      
Sbjct: 209 KGEVYGIAARSYCATPRSEEPWIHSHLELRDADGVAQPGYGWIFPLGNGLANVGCGALST 268

Query: 222 DGQTRFTTLKEKMSAF----QFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGF 277
           D +      K+ +  +    + ++G        + L P           N  LIG+AA  
Sbjct: 269 DRRPARINTKKLLGLYAQQCRPEWGFGAPDRVASALLPMGGAVSGVAGRNWMLIGDAAAC 328

Query: 278 ISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPAL 337
           ++  + EGI Y +++  +    L          Y      +  + +G+      + A  L
Sbjct: 329 VNPLNGEGIDYGMETARLAVECL-----GAGKDYTLLWPDVLRREYGEAFGLARMLARLL 383


  Database: uniref50.fasta
    Posted date:  Mar 8, 2010 10:38 AM
  Number of letters in database: 1,040,396,356
  Number of sequences in database:  3,077,464
  
Lambda     K      H
   0.315    0.164    0.472 

Lambda     K      H
   0.267   0.0505    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,080,807,699
Number of Sequences: 3077464
Number of extensions: 88838233
Number of successful extensions: 470130
Number of sequences better than 1.0e-01: 250
Number of HSP's better than  0.1 without gapping: 6678
Number of HSP's successfully gapped in prelim test: 6488
Number of HSP's that attempted gapping in prelim test: 440652
Number of HSP's gapped (non-prelim): 20239
length of query: 354
length of database: 1,040,396,356
effective HSP length: 130
effective length of query: 224
effective length of database: 640,326,036
effective search space: 143433032064
effective search space used: 143433032064
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (20.8 bits)
S2: 94 (40.5 bits)
