Phyre 2 Results for P77756

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Email | l.a.kelley@imperial.ac.uk
Description | P77756
Date | Thu Jan 5 12:32:35 GMT 2012
Unique Job ID | 4c402f75401fc649

Summary |

Top model
Image coloured by rainbow N → C terminus
| Close Jmol

Model (left) based on template d2pg3a1
Top template information
Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases
Confidence and coverage
Confidence: | 100.0% | Coverage: | 96%
221 residues ( 96% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | K | R | A | V | V | V | F | S | G | G | Q | D | S | T | T | C | L | V | Q | A | L | Q | Q | Y | D | E | V | H | C | V | T | F | D | Y | G | Q | R | H | R | A | E | I | D | V | A | R | E | L | A | L | K | L | G | A | R | A | H | K | V
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | L | D | V | T | L | L | N | E | L | A | V | S | S | L | T | R | D | S | I | P | V | P | D | Y | E | P | E | A | D | G | I | P | N | T | F | V | P | G | R | N | I | L | F | L | T | L | A | A | I | Y | A | Y | Q | V | K | A | E | A | V | I
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  | ? | ? | ? |  |  |  |  | ? | ? |  | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | T | G | V | C | E | T | D | F | S | G | Y | P | D | C | R | D | E | F | V | K | A | L | N | H | A | V | S | L | G | M | A | K | D | I | R | F | E | T | P | L | M | W | I | D | K | A | E | T | W | A | L | A | D | Y | Y | G | K | L | D | L
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | .
Sequence |  | V | R | N | E | T | L | T | C | Y | N | G | F | K | G | D | G | C | G | H | C | A | A | C | N | L | R | A | N | G | L | N | H | Y | L | A | D | K | P | T | V | M | A | A | M | K | Q | K | T | G | L | R
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| d2pg3a1 |

### PDB 2pg3 chain A domain 1

Region: 1 - 230
Aligned: 221
Modelled: 229
Confidence: 100.0%
Identity: 82%
Fold: Adenine nucleotide alpha hydrolase-like
Superfamily: Adenine nucleotide alpha hydrolases-like
Family: N-type ATP pyrophosphatases

Phyre2
2 |
| c3bl5E_ |

### PDB 3bl5 chain E

Region: 2 - 213
Aligned: 194
Modelled: 194
Confidence: 100.0%
Identity: 57%
PDB header:hydrolase
Chain: E: PDB Molecule:queuosine biosynthesis protein quec;
PDBTitle: crystal structure of quec from bacillus subtilis: an enzyme2 involved in preq1 biosynthesis

Phyre2
3 |
| c2c5sA_ |

### PDB 2c5s chain A

Region: 3 - 179
Aligned: 151
Modelled: 160
Confidence: 99.9%
Identity: 21%
PDB header:rna-binding protein
Chain: A: PDB Molecule:probable thiamine biosynthesis protein thii;
PDBTitle: crystal structure of bacillus anthracis thii, a trna-2 modifying enzyme containing the predicted rna-binding3 thump domain

Phyre2
4 |
| d2c5sa1 |

### PDB 2c5s chain A domain 1

Region: 3 - 191
Aligned: 164
Modelled: 177
Confidence: 99.8%
Identity: 18%
Fold: Adenine nucleotide alpha hydrolase-like
Superfamily: Adenine nucleotide alpha hydrolases-like
Family: ThiI-like

Phyre2
5 |
| c2hmaA_ |

### PDB 2hma chain A

Region: 2 - 194
Aligned: 180
Modelled: 180
Confidence: 99.8%
Identity: 21%
PDB header:transferase
Chain: A: PDB Molecule:probable trna (5-methylaminomethyl-2-thiouridylate)-
PDBTitle: the crystal structure of trna (5-methylaminomethyl-2-thiouridylate)-2 methyltransferase trmu from streptococcus pneumoniae

Phyre2
6 |
| c2derA_ |

### PDB 2der chain A

Region: 2 - 178
Aligned: 163
Modelled: 170
Confidence: 99.8%
Identity: 21%
PDB header:transferase/rna
Chain: A: PDB Molecule:trna-specific 2-thiouridylase mnma;
PDBTitle: cocrystal structure of an rna sulfuration enzyme mnma and2 trna-glu in the initial trna binding state

Phyre2
7 |
| d1gpma1 |

### PDB 1gpm chain A domain 1

Region: 2 - 183
Aligned: 148
Modelled: 148
Confidence: 99.8%
Identity: 14%
Fold: Adenine nucleotide alpha hydrolase-like
Superfamily: Adenine nucleotide alpha hydrolases-like
Family: N-type ATP pyrophosphatases

Phyre2
8 |
| c2vxoB_ |

### PDB 2vxo chain B

Region: 2 - 184
Aligned: 174
Modelled: 183
Confidence: 99.8%
Identity: 20%
PDB header:ligase
Chain: B: PDB Molecule:gmp synthase [glutamine-hydrolyzing];
PDBTitle: human gmp synthetase in complex with xmp

Phyre2
9 |
| d1k92a1 |

### PDB 1k92 chain A domain 1

Region: 2 - 187
Aligned: 170
Modelled: 186
Confidence: 99.8%
Identity: 16%
Fold: Adenine nucleotide alpha hydrolase-like
Superfamily: Adenine nucleotide alpha hydrolases-like
Family: N-type ATP pyrophosphatases

Phyre2
10 |
| c2dplA_ |

### PDB 2dpl chain A

Region: 2 - 183
Aligned: 141
Modelled: 141
Confidence: 99.8%
Identity: 26%
PDB header:ligase
Chain: A: PDB Molecule:gmp synthase [glutamine-hydrolyzing] subunit b;
PDBTitle: crystal structure of the gmp synthase from pyrococcus horikoshii ot3

Phyre2
11 |
| d1j20a1 |

### PDB 1j20 chain A domain 1

Region: 3 - 181
Aligned: 160
Modelled: 173
Confidence: 99.8%
Identity: 24%
Fold: Adenine nucleotide alpha hydrolase-like
Superfamily: Adenine nucleotide alpha hydrolases-like
Family: N-type ATP pyrophosphatases

Phyre2
12 |
| c2ywcC_ |

### PDB 2ywc chain C

Region: 2 - 185
Aligned: 146
Modelled: 146
Confidence: 99.8%
Identity: 17%
PDB header:ligase
Chain: C: PDB Molecule:gmp synthase [glutamine-hydrolyzing];
PDBTitle: crystal structure of gmp synthetase from thermus thermophilus in2 complex with xmp

Phyre2
13 |
| d1vl2a1 |

### PDB 1vl2 chain A domain 1

Region: 2 - 178
Aligned: 158
Modelled: 177
Confidence: 99.7%
Identity: 17%
Fold: Adenine nucleotide alpha hydrolase-like
Superfamily: Adenine nucleotide alpha hydrolases-like
Family: N-type ATP pyrophosphatases

Phyre2
14 |
| c2nz2A_ |

### PDB 2nz2 chain A

Region: 2 - 194
Aligned: 178
Modelled: 186
Confidence: 99.7%
Identity: 16%
PDB header:ligase
Chain: A: PDB Molecule:argininosuccinate synthase;
PDBTitle: crystal structure of human argininosuccinate synthase in complex with2 aspartate and citrulline

Phyre2
15 |
| c3tqiB_ |

### PDB 3tqi chain B

Region: 2 - 184
Aligned: 144
Modelled: 144
Confidence: 99.7%
Identity: 21%
PDB header:ligase
Chain: B: PDB Molecule:gmp synthase [glutamine-hydrolyzing];
PDBTitle: structure of the gmp synthase (guaa) from coxiella burnetii

Phyre2
16 |
| c3k32D_ |

### PDB 3k32 chain D

Region: 2 - 181
Aligned: 153
Modelled: 154
Confidence: 99.7%
Identity: 21%
PDB header:transferase
Chain: D: PDB Molecule:uncharacterized protein mj0690;
PDBTitle: the crystal structure of predicted subunit of trna2 methyltransferase from methanocaldococcus jannaschii dsm

Phyre2
17 |
| c1vl2C_ |

### PDB 1vl2 chain C

Region: 2 - 195
Aligned: 176
Modelled: 194
Confidence: 99.7%
Identity: 11%
PDB header:ligase
Chain: C: PDB Molecule:argininosuccinate synthase;
PDBTitle: crystal structure of argininosuccinate synthase (tm1780) from2 thermotoga maritima at 1.65 a resolution

Phyre2
18 |
| c1gpmD_ |

### PDB 1gpm chain D

Region: 2 - 184
Aligned: 147
Modelled: 147
Confidence: 99.7%
Identity: 14%
PDB header:transferase (glutamine amidotransferase)
Chain: D: PDB Molecule:gmp synthetase;
PDBTitle: escherichia coli gmp synthetase complexed with amp and pyrophosphate

Phyre2
19 |
| c1k97A_ |

### PDB 1k97 chain A

Region: 2 - 195
Aligned: 175
Modelled: 175
Confidence: 99.7%
Identity: 17%
PDB header:ligase
Chain: A: PDB Molecule:argininosuccinate synthase;
PDBTitle: crystal structure of e. coli argininosuccinate synthetase in complex2 with aspartate and citrulline

Phyre2
20 |
| c1kh2D_ |

### PDB 1kh2 chain D

Region: 3 - 178
Aligned: 158
Modelled: 170
Confidence: 99.7%
Identity: 25%
PDB header:ligase
Chain: D: PDB Molecule:argininosuccinate synthetase;
PDBTitle: crystal structure of thermus thermophilus hb82 argininosuccinate synthetase in complex with atp

Phyre2
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Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | d2pg3a1 |
|  | 100.0 | 82 | Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases
2 | c3bl5E_ |
|  | 100.0 | 57 | PDB header:hydrolase Chain: E: PDB Molecule:queuosine biosynthesis protein quec; PDBTitle: crystal structure of quec from bacillus subtilis: an enzyme2 involved in preq1 biosynthesis
3 | c2c5sA_ |
|  | 99.9 | 21 | PDB header:rna-binding protein Chain: A: PDB Molecule:probable thiamine biosynthesis protein thii; PDBTitle: crystal structure of bacillus anthracis thii, a trna-2 modifying enzyme containing the predicted rna-binding3 thump domain
4 | d2c5sa1 |
|  | 99.8 | 18 | Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ThiI-like
5 | c2hmaA_ |
|  | 99.8 | 21 | PDB header:transferase Chain: A: PDB Molecule:probable trna (5-methylaminomethyl-2-thiouridylate)- PDBTitle: the crystal structure of trna (5-methylaminomethyl-2-thiouridylate)-2 methyltransferase trmu from streptococcus pneumoniae
6 | c2derA_ |
|  | 99.8 | 21 | PDB header:transferase/rna Chain: A: PDB Molecule:trna-specific 2-thiouridylase mnma; PDBTitle: cocrystal structure of an rna sulfuration enzyme mnma and2 trna-glu in the initial trna binding state
7 | d1gpma1 |
|  | 99.8 | 14 | Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases
8 | c2vxoB_ |
|  | 99.8 | 20 | PDB header:ligase Chain: B: PDB Molecule:gmp synthase [glutamine-hydrolyzing]; PDBTitle: human gmp synthetase in complex with xmp
9 | d1k92a1 |
|  | 99.8 | 16 | Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases
10 | c2dplA_ |
|  | 99.8 | 26 | PDB header:ligase Chain: A: PDB Molecule:gmp synthase [glutamine-hydrolyzing] subunit b; PDBTitle: crystal structure of the gmp synthase from pyrococcus horikoshii ot3
11 | d1j20a1 |
|  | 99.8 | 24 | Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases
12 | c2ywcC_ |
|  | 99.8 | 17 | PDB header:ligase Chain: C: PDB Molecule:gmp synthase [glutamine-hydrolyzing]; PDBTitle: crystal structure of gmp synthetase from thermus thermophilus in2 complex with xmp
13 | d1vl2a1 |
|  | 99.7 | 17 | Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases
14 | c2nz2A_ |
|  | 99.7 | 16 | PDB header:ligase Chain: A: PDB Molecule:argininosuccinate synthase; PDBTitle: crystal structure of human argininosuccinate synthase in complex with2 aspartate and citrulline
15 | c3tqiB_ |
|  | 99.7 | 21 | PDB header:ligase Chain: B: PDB Molecule:gmp synthase [glutamine-hydrolyzing]; PDBTitle: structure of the gmp synthase (guaa) from coxiella burnetii
16 | c3k32D_ |
|  | 99.7 | 21 | PDB header:transferase Chain: D: PDB Molecule:uncharacterized protein mj0690; PDBTitle: the crystal structure of predicted subunit of trna2 methyltransferase from methanocaldococcus jannaschii dsm
17 | c1vl2C_ |
|  | 99.7 | 11 | PDB header:ligase Chain: C: PDB Molecule:argininosuccinate synthase; PDBTitle: crystal structure of argininosuccinate synthase (tm1780) from2 thermotoga maritima at 1.65 a resolution
18 | c1gpmD_ |
|  | 99.7 | 14 | PDB header:transferase (glutamine amidotransferase) Chain: D: PDB Molecule:gmp synthetase; PDBTitle: escherichia coli gmp synthetase complexed with amp and pyrophosphate
19 | c1k97A_ |
|  | 99.7 | 17 | PDB header:ligase Chain: A: PDB Molecule:argininosuccinate synthase; PDBTitle: crystal structure of e. coli argininosuccinate synthetase in complex2 with aspartate and citrulline
20 | c1kh2D_ |
|  | 99.7 | 25 | PDB header:ligase Chain: D: PDB Molecule:argininosuccinate synthetase; PDBTitle: crystal structure of thermus thermophilus hb82 argininosuccinate synthetase in complex with atp
21 | c3p52B_ |
| not modelled | 99.7 | 16 | PDB header:ligase Chain: B: PDB Molecule:nh(3)-dependent nad(+) synthetase; PDBTitle: nh3-dependent nad synthetase from campylobacter jejuni subsp. jejuni2 nctc 11168 in complex with the nitrate ion
22 | d1vbka1 |
| not modelled | 99.7 | 10 | Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ThiI-like
23 | c2e21A_ |
| not modelled | 99.7 | 17 | PDB header:ligase Chain: A: PDB Molecule:trna(ile)-lysidine synthase; PDBTitle: crystal structure of tils in a complex with amppnp from aquifex2 aeolicus.
24 | c3fiuD_ |
| not modelled | 99.7 | 16 | PDB header:ligase Chain: D: PDB Molecule:nh(3)-dependent nad(+) synthetase; PDBTitle: structure of nmn synthetase from francisella tularensis
25 | d1ni5a1 |
| not modelled | 99.7 | 24 | Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:PP-loop ATPase
26 | c3a2kB_ |
| not modelled | 99.7 | 16 | PDB header:ligase/rna Chain: B: PDB Molecule:trna(ile)-lysidine synthase; PDBTitle: crystal structure of tils complexed with trna
27 | d1wy5a1 |
| not modelled | 99.7 | 18 | Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:PP-loop ATPase
28 | c1ni5A_ |
| not modelled | 99.6 | 22 | PDB header:cell cycle Chain: A: PDB Molecule:putative cell cycle protein mesj; PDBTitle: structure of the mesj pp-atpase from escherichia coli
29 | c3uowB_ |
| not modelled | 99.6 | 14 | PDB header:ligase Chain: B: PDB Molecule:gmp synthetase; PDBTitle: crystal structure of pf10_0123, a gmp synthetase from plasmodium2 falciparum
30 | c1vbkA_ |
| not modelled | 99.6 | 14 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein ph1313; PDBTitle: crystal structure of ph1313 from pyrococcus horikoshii ot3
31 | d1xnga1 |
| not modelled | 99.6 | 16 | Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases
32 | c2e18B_ |
| not modelled | 99.5 | 17 | PDB header:ligase Chain: B: PDB Molecule:nh(3)-dependent nad(+) synthetase; PDBTitle: crystal structure of project ph0182 from pyrococcus horikoshii ot3
33 | d1sura_ |
| not modelled | 99.5 | 13 | Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:PAPS reductase-like
34 | c3q4gA_ |
| not modelled | 99.4 | 19 | PDB header:ligase Chain: A: PDB Molecule:nh(3)-dependent nad(+) synthetase; PDBTitle: structure of nad synthetase from vibrio cholerae
35 | c2o8vA_ |
| not modelled | 99.4 | 14 | PDB header:oxidoreductase Chain: A: PDB Molecule:phosphoadenosine phosphosulfate reductase; PDBTitle: paps reductase in a covalent complex with thioredoxin c35a
36 | d1ru8a_ |
| not modelled | 99.4 | 18 | Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases
37 | d1kqpa_ |
| not modelled | 99.4 | 15 | Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases
38 | c3dpiA_ |
| not modelled | 99.3 | 19 | PDB header:ligase Chain: A: PDB Molecule:nad+ synthetase; PDBTitle: crystal structure of nad+ synthetase from burkholderia pseudomallei
39 | d1wxia1 |
| not modelled | 99.2 | 13 | Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases
40 | c3n05B_ |
| not modelled | 99.1 | 18 | PDB header:ligase Chain: B: PDB Molecule:nh(3)-dependent nad(+) synthetase; PDBTitle: crystal structure of nh3-dependent nad+ synthetase from streptomyces2 avermitilis
41 | d2d13a1 |
| not modelled | 99.0 | 17 | Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases
42 | c2goyC_ |
| not modelled | 99.0 | 17 | PDB header:oxidoreductase Chain: C: PDB Molecule:adenosine phosphosulfate reductase; PDBTitle: crystal structure of assimilatory adenosine 5'-2 phosphosulfate reductase with bound aps
43 | c2oq2B_ |
| not modelled | 99.0 | 10 | PDB header:oxidoreductase Chain: B: PDB Molecule:phosphoadenosine phosphosulfate reductase; PDBTitle: crystal structure of yeast paps reductase with pap, a product complex
44 | d1zuna1 |
| not modelled | 98.9 | 11 | Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:PAPS reductase-like
45 | c1zunA_ |
| not modelled | 98.8 | 11 | PDB header:transferase Chain: A: PDB Molecule:sulfate adenylyltransferase subunit 2; PDBTitle: crystal structure of a gtp-regulated atp sulfurylase2 heterodimer from pseudomonas syringae
46 | c1ct9D_ |
| not modelled | 98.6 | 17 | PDB header:ligase Chain: D: PDB Molecule:asparagine synthetase b; PDBTitle: crystal structure of asparagine synthetase b from2 escherichia coli
47 | d1jgta1 |
| not modelled | 98.5 | 20 | Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases
48 | d1q15a1 |
| not modelled | 98.5 | 15 | Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases
49 | d1ct9a1 |
| not modelled | 98.5 | 18 | Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases
50 | c3ilvA_ |
| not modelled | 98.2 | 18 | PDB header:ligase Chain: A: PDB Molecule:glutamine-dependent nad(+) synthetase; PDBTitle: crystal structure of a glutamine-dependent nad(+) synthetase2 from cytophaga hutchinsonii
51 | c3dlaD_ |
| not modelled | 98.2 | 17 | PDB header:ligase Chain: D: PDB Molecule:glutamine-dependent nad(+) synthetase; PDBTitle: x-ray crystal structure of glutamine-dependent nad+ synthetase from2 mycobacterium tuberculosis bound to naad+ and don
52 | c1m1zB_ |
| not modelled | 98.1 | 26 | PDB header:hydrolase Chain: B: PDB Molecule:beta-lactam synthetase; PDBTitle: beta-lactam synthetase apo enzyme
53 | c1q15A_ |
| not modelled | 98.1 | 16 | PDB header:biosynthetic protein Chain: A: PDB Molecule:cara; PDBTitle: carbapenam synthetase
54 | c3g59A_ |
| not modelled | 98.1 | 16 | PDB header:transferase Chain: A: PDB Molecule:fmn adenylyltransferase; PDBTitle: crystal structure of candida glabrata fmn2 adenylyltransferase in complex with atp
55 | c2wsiA_ |
| not modelled | 97.7 | 17 | PDB header:transferase Chain: A: PDB Molecule:fad synthetase; PDBTitle: crystal structure of yeast fad synthetase (fad1) in complex2 with fad
56 | c2ejbA_ |
| not modelled | 79.4 | 13 | PDB header:lyase Chain: A: PDB Molecule:probable aromatic acid decarboxylase; PDBTitle: crystal structure of phenylacrylic acid decarboxylase from2 aquifex aeolicus
57 | c2c40B_ |
| not modelled | 79.4 | 21 | PDB header:hydrolase Chain: B: PDB Molecule:inosine-uridine preferring nucleoside hydrolase family PDBTitle: crystal structure of inosine-uridine preferring nucleoside2 hydrolase from bacillus anthracis at 2.2a resolution
58 | c3fojA_ |
| not modelled | 72.1 | 13 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of ssp1007 from staphylococcus2 saprophyticus subsp. saprophyticus. northeast structural3 genomics target syr101a.
59 | c3louB_ |
| not modelled | 69.6 | 11 | PDB header:hydrolase Chain: B: PDB Molecule:formyltetrahydrofolate deformylase; PDBTitle: crystal structure of formyltetrahydrofolate deformylase (yp_105254.1)2 from burkholderia mallei atcc 23344 at 1.90 a resolution
60 | c3p9xB_ |
| not modelled | 68.6 | 17 | PDB header:transferase Chain: B: PDB Molecule:phosphoribosylglycinamide formyltransferase; PDBTitle: crystal structure of phosphoribosylglycinamide formyltransferase from2 bacillus halodurans
61 | d2fug11 |
| not modelled | 68.5 | 44 | Fold:Bromodomain-like Superfamily:Nqo1C-terminal domain-like Family:Nqo1C-terminal domain-like
62 | c3fz0C_ |
| not modelled | 66.7 | 17 | PDB header:hydrolase Chain: C: PDB Molecule:nucleoside hydrolase, putative; PDBTitle: inosine-guanosine nucleoside hydrolase (ig-nh)
63 | c1wv9B_ |
| not modelled | 65.0 | 13 | PDB header:structural genomics, unknown function Chain: B: PDB Molecule:rhodanese homolog tt1651; PDBTitle: crystal structure of rhodanese homolog tt1651 from an2 extremely thermophilic bacterium thermus thermophilus hb8
64 | c3o1lB_ |
| not modelled | 61.7 | 18 | PDB header:hydrolase Chain: B: PDB Molecule:formyltetrahydrofolate deformylase; PDBTitle: crystal structure of a formyltetrahydrofolate deformylase (pspto_4314)2 from pseudomonas syringae pv. tomato str. dc3000 at 2.20 a resolution
65 | c3n0vD_ |
| not modelled | 59.4 | 14 | PDB header:hydrolase Chain: D: PDB Molecule:formyltetrahydrofolate deformylase; PDBTitle: crystal structure of a formyltetrahydrofolate deformylase (pp_0327)2 from pseudomonas putida kt2440 at 2.25 a resolution
66 | d1vhqa_ |
| not modelled | 53.7 | 27 | Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:DJ-1/PfpI
67 | d2j13a1 |
| not modelled | 48.7 | 13 | Fold:7-stranded beta/alpha barrel Superfamily:Glycoside hydrolase/deacetylase Family:NodB-like polysaccharide deacetylase
68 | c3nbmA_ |
| not modelled | 47.1 | 16 | PDB header:transferase Chain: A: PDB Molecule:pts system, lactose-specific iibc components; PDBTitle: the lactose-specific iib component domain structure of the2 phosphoenolpyruvate:carbohydrate phosphotransferase system (pts) from3 streptococcus pneumoniae.
69 | d1yt8a4 |
| not modelled | 43.6 | 20 | Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese)
70 | c2fugA_ |
| not modelled | 43.2 | 40 | PDB header:oxidoreductase Chain: A: PDB Molecule:nadh-quinone oxidoreductase chain 1; PDBTitle: crystal structure of the hydrophilic domain of respiratory complex i2 from thermus thermophilus
71 | d2hy5b1 |
| not modelled | 40.5 | 19 | Fold:DsrEFH-like Superfamily:DsrEFH-like Family:DsrEF-like
72 | c3etjB_ |
| not modelled | 38.0 | 23 | PDB header:lyase Chain: B: PDB Molecule:phosphoribosylaminoimidazole carboxylase atpase PDBTitle: crystal structure e. coli purk in complex with mg, adp, and2 pi
73 | c1zxxA_ |
| not modelled | 36.8 | 32 | PDB header:transferase Chain: A: PDB Molecule:6-phosphofructokinase; PDBTitle: the crystal structure of phosphofructokinase from lactobacillus2 delbrueckii
74 | d1iiba_ |
| not modelled | 36.7 | 14 | Fold:Phosphotyrosine protein phosphatases I-like Superfamily:PTS system IIB component-like Family:PTS system, Lactose/Cellobiose specific IIB subunit
75 | c3nrbD_ |
| not modelled | 36.2 | 15 | PDB header:hydrolase Chain: D: PDB Molecule:formyltetrahydrofolate deformylase; PDBTitle: crystal structure of a formyltetrahydrofolate deformylase (puru,2 pp_1943) from pseudomonas putida kt2440 at 2.05 a resolution
76 | d1ffva1 |
| not modelled | 35.5 | 26 | Fold:CO dehydrogenase ISP C-domain like Superfamily:CO dehydrogenase ISP C-domain like Family:CO dehydrogenase ISP C-domain like
77 | c2l2qA_ |
| not modelled | 35.2 | 8 | PDB header:transferase Chain: A: PDB Molecule:pts system, cellobiose-specific iib component (cela); PDBTitle: solution structure of cellobiose-specific phosphotransferase iib2 component protein from borrelia burgdorferi
78 | c2jtqA_ |
| not modelled | 34.2 | 10 | PDB header:transferase Chain: A: PDB Molecule:phage shock protein e; PDBTitle: rhodanese from e.coli
79 | d1t3qa1 |
| not modelled | 34.0 | 22 | Fold:CO dehydrogenase ISP C-domain like Superfamily:CO dehydrogenase ISP C-domain like Family:CO dehydrogenase ISP C-domain like
80 | d1tq8a_ |
| not modelled | 33.7 | 20 | Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:Universal stress protein-like
81 | c2k0zA_ |
| not modelled | 33.4 | 7 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein hp1203; PDBTitle: solution nmr structure of protein hp1203 from helicobacter pylori2 26695. northeast structural genomics consortium (nesg) target3 pt1/ontario center for structural proteomics target hp1203
82 | d4pfka_ |
| not modelled | 33.4 | 45 | Fold:Phosphofructokinase Superfamily:Phosphofructokinase Family:Phosphofructokinase
83 | c2iy3A_ |
| not modelled | 33.2 | 19 | PDB header:rna-binding Chain: A: PDB Molecule:signal recognition particle protein ffh; PDBTitle: structure of the e. coli signal recognition particle2 bound to a translating ribosome
84 | c3g5jA_ |
| not modelled | 33.1 | 14 | PDB header:nucleotide binding protein Chain: A: PDB Molecule:putative atp/gtp binding protein; PDBTitle: crystal structure of n-terminal domain of putative atp/gtp binding2 protein from clostridium difficile 630
85 | c2jyiA_ |
| not modelled | 32.8 | 33 | PDB header:transcription Chain: A: PDB Molecule:zinc finger protein hrx; PDBTitle: solution structure of mll cxxc domain
86 | c1jr3E_ |
| not modelled | 32.1 | 33 | PDB header:transferase Chain: E: PDB Molecule:dna polymerase iii, delta' subunit; PDBTitle: crystal structure of the processivity clamp loader gamma2 complex of e. coli dna polymerase iii
87 | c2dzdB_ |
| not modelled | 31.7 | 10 | PDB header:ligase Chain: B: PDB Molecule:pyruvate carboxylase; PDBTitle: crystal structure of the biotin carboxylase domain of2 pyruvate carboxylase
88 | c3noyA_ |
| not modelled | 31.7 | 20 | PDB header:oxidoreductase Chain: A: PDB Molecule:4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; PDBTitle: crystal structure of ispg (gcpe)
89 | c2x7vA_ |
| not modelled | 31.6 | 11 | PDB header:hydrolase Chain: A: PDB Molecule:probable endonuclease 4; PDBTitle: crystal structure of thermotoga maritima endonuclease iv in2 the presence of zinc
90 | c1gqqA_ |
| not modelled | 31.5 | 10 | PDB header:cell wall biosynthesis Chain: A: PDB Molecule:udp-n-acetylmuramate-l-alanine ligase; PDBTitle: murc - crystal structure of the apo-enzyme from haemophilus2 influenzae
91 | d2d1pb1 |
| not modelled | 31.4 | 28 | Fold:DsrEFH-like Superfamily:DsrEFH-like Family:DsrEF-like
92 | c3c1oA_ |
| not modelled | 31.3 | 9 | PDB header:oxidoreductase Chain: A: PDB Molecule:eugenol synthase; PDBTitle: the multiple phenylpropene synthases in both clarkia2 breweri and petunia hybrida represent two distinct lineages
93 | c3dhnA_ |
| not modelled | 29.6 | 29 | PDB header:isomerase, lyase Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase; PDBTitle: crystal structure of the putative epimerase q89z24_bactn2 from bacteroides thetaiotaomicron. northeast structural3 genomics consortium target btr310.
94 | c2ehdB_ |
| not modelled | 29.2 | 24 | PDB header:oxidoreductase Chain: B: PDB Molecule:oxidoreductase, short-chain dehydrogenase/reductase family; PDBTitle: crystal structure analysis of oxidoreductase
95 | c3qmhA_ |
| not modelled | 28.5 | 45 | PDB header:dna binding protein/dna Chain: A: PDB Molecule:cpg-binding protein; PDBTitle: structural basis of selective binding of non-methylated cpg islands2 (dna-tcga) by the cxxc domain of cfp1
96 | c3mcuF_ |
| not modelled | 27.8 | 27 | PDB header:oxidoreductase Chain: F: PDB Molecule:dipicolinate synthase, b chain; PDBTitle: crystal structure of the dipicolinate synthase chain b from2 bacillus cereus. northeast structural genomics consortium3 target bcr215.
97 | c3qjgD_ |
| not modelled | 27.7 | 17 | PDB header:oxidoreductase Chain: D: PDB Molecule:epidermin biosynthesis protein epid; PDBTitle: epidermin biosynthesis protein epid from staphylococcus aureus
98 | c2q1wC_ |
| not modelled | 27.3 | 22 | PDB header:sugar binding protein Chain: C: PDB Molecule:putative nucleotide sugar epimerase/ dehydratase; PDBTitle: crystal structure of the bordetella bronchiseptica enzyme wbmh in2 complex with nad+
99 | c3p19A_ |
| not modelled | 27.1 | 18 | PDB header:oxidoreductase Chain: A: PDB Molecule:putative blue fluorescent protein; PDBTitle: improved nadph-dependent blue fluorescent protein
100 | c3gpiA_ |
| not modelled | 27.1 | 13 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase; PDBTitle: structure of putative nad-dependent epimerase/dehydratase2 from methylobacillus flagellatus
101 | d1jroa1 |
| not modelled | 26.7 | 44 | Fold:CO dehydrogenase ISP C-domain like Superfamily:CO dehydrogenase ISP C-domain like Family:CO dehydrogenase ISP C-domain like
102 | c3emeA_ |
| not modelled | 26.6 | 17 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:rhodanese-like domain protein; PDBTitle: crystal structure of rhodanese-like domain protein from2 staphylococcus aureus
103 | c2kakA_ |
| not modelled | 26.5 | 54 | PDB header:metal binding protein Chain: A: PDB Molecule:ec protein i/ii; PDBTitle: solution structure of the beta-e-domain of wheat ec-12 metallothionein
104 | c3ilmD_ |
| not modelled | 26.2 | 10 | PDB header:structural genomics, unknown function Chain: D: PDB Molecule:alr3790 protein; PDBTitle: crystal structure of the alr3790 protein from anabaena sp. northeast2 structural genomics consortium target nsr437h
105 | c3k2qA_ |
| not modelled | 26.1 | 45 | PDB header:transferase Chain: A: PDB Molecule:pyrophosphate-dependent phosphofructokinase; PDBTitle: crystal structure of pyrophosphate-dependent2 phosphofructokinase from marinobacter aquaeolei, northeast3 structural genomics consortium target mqr88
106 | c2dcqA_ |
| not modelled | 26.1 | 6 | PDB header:unknown function Chain: A: PDB Molecule:putative protein at4g01050; PDBTitle: fully automated nmr structure determination of the2 rhodanese homology domain at4g01050(175-295) from3 arabidopsis thaliana
107 | c3mt0A_ |
| not modelled | 25.8 | 14 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein pa1789; PDBTitle: the crystal structure of a functionally unknown protein pa1789 from2 pseudomonas aeruginosa pao1
108 | d1v97a1 |
| not modelled | 25.8 | 22 | Fold:CO dehydrogenase ISP C-domain like Superfamily:CO dehydrogenase ISP C-domain like Family:CO dehydrogenase ISP C-domain like
109 | c1xxhB_ |
| not modelled | 24.7 | 26 | PDB header:transferase Chain: B: PDB Molecule:dna polymerase iii subunit gamma; PDBTitle: atpgs bound e. coli clamp loader complex
110 | c1j8yF_ |
| not modelled | 24.2 | 14 | PDB header:signaling protein Chain: F: PDB Molecule:signal recognition 54 kda protein; PDBTitle: signal recognition particle conserved gtpase domain from a.2 ambivalens t112a mutant
111 | c3swrA_ |
| not modelled | 24.1 | 46 | PDB header:transferase Chain: A: PDB Molecule:dna (cytosine-5)-methyltransferase 1; PDBTitle: structure of human dnmt1 (601-1600) in complex with sinefungin
112 | d1rm6c1 |
| not modelled | 23.9 | 19 | Fold:CO dehydrogenase ISP C-domain like Superfamily:CO dehydrogenase ISP C-domain like Family:CO dehydrogenase ISP C-domain like
113 | d1n62a1 |
| not modelled | 23.8 | 19 | Fold:CO dehydrogenase ISP C-domain like Superfamily:CO dehydrogenase ISP C-domain like Family:CO dehydrogenase ISP C-domain like
114 | c2fsxA_ |
| not modelled | 23.7 | 13 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:cog0607: rhodanese-related sulfurtransferase; PDBTitle: crystal structure of rv0390 from m. tuberculosis
115 | c1t3qD_ |
| not modelled | 23.3 | 22 | PDB header:oxidoreductase Chain: D: PDB Molecule:quinoline 2-oxidoreductase small subunit; PDBTitle: crystal structure of quinoline 2-oxidoreductase from pseudomonas2 putida 86
116 | d1dgja1 |
| not modelled | 23.1 | 33 | Fold:CO dehydrogenase ISP C-domain like Superfamily:CO dehydrogenase ISP C-domain like Family:CO dehydrogenase ISP C-domain like
117 | d1ezra_ |
| not modelled | 22.9 | 19 | Fold:Nucleoside hydrolase Superfamily:Nucleoside hydrolase Family:Nucleoside hydrolase
118 | d1yt8a1 |
| not modelled | 22.9 | 17 | Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese)
119 | c3lqkA_ |
| not modelled | 22.8 | 10 | PDB header:oxidoreductase Chain: A: PDB Molecule:dipicolinate synthase subunit b; PDBTitle: crystal structure of dipicolinate synthase subunit b from bacillus2 halodurans c
120 | d1pfka_ |
| not modelled | 22.4 | 39 | Fold:Phosphofructokinase Superfamily:Phosphofructokinase Family:Phosphofructokinase

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0