>ss_pred
CCEEEEEECCCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCHHHCEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCC
>ss_conf
956988613856799999999974994799994488983788999999999809963798402024321111112220111000002456663146301079999999999863998799611234445767889899999999996307789679840238998999999975050122055214132689988898475679999999983899873352024417899
>batch____
MKRAVVVFSGGQDSTTCLVQALQQYDEVHCVTFDYGQRHRAEIDVARELALKLGARAHKVLDVTLLNELAVSSLTRDSIPVPDYEPEADGIPNTFVPGRNILFLTLAAIYAYQVKAEAVITGVCETDFSGYPDCRDEFVKALNHAVSLGMAKDIRFETPLMWIDKAETWALADYYGKLDLVRNETLTCYNGFKGDGCGHCAACNLRANGLNHYLADKPTVMAAMKQKTGLR
>UniRef50_A6LIS9(7-219:224) 7-cyano-7-deazaguanine synthase n=88 Tax=Bacteria RepID=QUEC_PARD8   E=1e-54 s/c=1.00 id=52% cov=92%
---ALVCFSGGQDSTTCLFWAKKHFSRVEAVCFTYGQKHSLEIEVARKIAADADV-PFQLLDVSLISQLDPNcSLTNASIEMDQEKPE-DSYPNTFVPGRNMVFLTFAAILARGKGIYHLVTGVSEADYSGYPDCRDTFVRSLNVTLNLAMDEQFVIHTPLMDRDKSEVWELSDELGVFDLVRTQTLTCYNGVMAEGCGHCPACKLRKDGLEKYLKRK--------------
>UniRef50_Q7M8H4(14-232:233) 7-cyano-7-deazaguanine synthase n=2 Tax=Campylobacterales RepID=QUEC_WOLSU  E=7e-45 s/c=0.83 id=47% cov=91%
---ALVVFSGGQDSTTCLGWAIKHFKSVEAITFDYGQRHRIEIEQSRLIAQKLGIKQF-ILEFDLFSKLGDSALleTSSDLKASPHRTKPH-LPASFVPNRNALFFTLAHAYAQREGLTHIITGISEADYSGYPDCREEFITHLERTLNLGSDSSILFAYPLLHRNKAQTFALAKECGVLDLVLEESHTCYNGDRshryewGYGCKECPACGLREKGWREYQA----------------
>UniRef50_Q0BQ87(18-246:252) 7-cyano-7-deazaguanine synthase n=76 Tax=Bacteria RepID=QUEC_GRABC   E=8e-44 s/c=0.78 id=48% cov=90%
---ALVLFSGGQDSTTCLAWALERFAHVETIGFTYGQRHSVEMECrgrVRQVLAHMSGRSgadwgsrlgdDHVLDLgNALHHVGQSALTGRS-PI---EIGQGGLPTSFVPGRNLIFLTYAAALGWRRGLRRMVGGMCETDYSGYPDCRDDTIKAMQLALNTGMEAHFVLETPLMWLTKAETWALADSLGGpalVALIEEETHTCYLGDRsqrhpwGYGCGECPACSLRAEGWREW------------------
>UniRef50_B2KDX5(269-475:484) ExsB protein n=1 Tax=Elusimicrobium minutum Pei191 RepID=B2KDX5_ELUMP  E=2e-34 s/c=0.71 id=42% cov=89%
-KKAVVLFSGGLDSTVCLYWALKEGYECYALSVAYGQKHLKEIEVAQRLAKQAGV-THKHIEINLPWLAEATSLVGGAeIPATPMEQIGKSIPSTYVPARNLIFVSLGASWADSIGAEAVVLGPNAVDYSGYPDCTPQFYKPLSEAVRVGTRLGKKFEilTPIIKLNKAEIVKLGR---KLGAPLEQTWTCYNGGE-KPCGVCESCKLRRKGF---------------------
>UniRef50_Q2N612(7-234:239) 7-cyano-7-deazaguanine synthase n=56 Tax=Bacteria RepID=QUEC_ERYLH   E=3e-27 s/c=0.54 id=40% cov=93%
-KAAAILLSGGLDSMVTAAIAQEQGYAVHALTIDYGQRHKVELQSARLIAAKIGAERHVEIEAD-LRALGGSALT-DDIDVPKCGVGND-IPVTYVPARNLVFLSLTTAFAEASGARDIFIGVNALDYSGYPDCRPEFIESFavtaNLATKAGVEESAPFKihAPLQHMTKAD---IARECARLGLESAWSWSCYDPLPGlKPCGACDSCRLRRKGFAEagladgldYPADAPPI-----------
>UniRef50_A3ZMY4(1-219:219) Predicted PP-loop superfamily ATPase n=1 Tax=Blastopirellula marina DSM 3645 RepID=A3ZMY4_9PLAN  E=5e-24 s/c=0.52 id=34% cov=94%
MSKVVAVVSGGMDSATLLYHLIDAGHDVRAISINYGQRHVKELDYARQLCDKVGV-PQIVADLSAINPLfGANSLSGREIEIPEGHYAEENMKLTVVPNRNMILLSVSIAWAISQECVAVAYGAHSGDHAIYPDCRPEFAAAMDQAAKLCDWSAVELWRPFVDIDKGD---IAQRGSELGVPYELTWTCYKGL-AEHCGKCGACVERKEAFaKHGLVDPTAYMA---------
>UniRef50_B8HQ99(2-213:229) 7-cyano-7-deazaguanine synthase n=1 Tax=Cyanothece sp. PCC 7425 RepID=QUEC_CYAP4  E=2e-23 s/c=0.52 id=35% cov=87%
--KIVILLSGGLDSTTVLYLARSLGHDCYALSFNYGQRHKQELAAAIAVAQLAGVIQHQVIsfDLGLWGGSALTDYTLDLPQNRAFKEMAEQIPITYVPARNTIFLSFALSYAEAIGATQVYAGMNAIDYSGYPDCRPDYIAAMQEVYRLGTkqgreGEPIQIITPLIDLTKPAIIQLGN---RLGVPWAKTWSCYSDGGGNdppvACGVCDSCRLR-------------------------
>UniRef50_B3G2Q8(16-213:222) Putative uncharacterized protein n=1 Tax=Pseudomonas aeruginosa RepID=B3G2Q8_PSEAE  E=4e-23 s/c=0.56 id=35% cov=84%
-RKIVVLHSGGLDSTVCLLLAHSRGHEVVSLGVSYNQHHHVELDYAAAQCARYGIE-RKIVSVAWSKPARVIPKNRSMAEI------KKGVSSAFLPGRNGIFLMLASAEAAGIGADEVWTGINSVDFSGYPDCRPEFIESFRKMLSYAIPKGPKLSAPLQKKSKPQIAKLAH---RLGLQRHDTWSCYRPKIAEAgfvpCGACDACKL--------------------------
>UniRef50_B9L187(8-214:226) ExsB protein n=1 Tax=Thermomicrobium roseum DSM 5159 RepID=B9L187_THERP  E=6e-23 s/c=0.53 id=39% cov=87%
-QRAVVLLSGGLDSTT-LAYLLDAYGFVlYGLSFRYGQRHERELEAARAIAEKLRFAEHRVVTIDLAQWGGSSLVGSGEIP----RQPTSGIPSTYVPVRNLVFLAIAHAYAEAIDADAVAIAVSQVDYSGYPDCRGEFLAAYQQAADLAsrrfveTGRRIPVLAPFLDVPKS---AIVRLGLRLGVDYAETWSCYRGGE-RPCQECDSCRLRAQAF---------------------
>UniRef50_C0CIL2(3-218:231) Putative uncharacterized protein n=1 Tax=Blautia hydrogenotrophica DSM 10507 RepID=C0CIL2_9FIRM  E=3e-22 s/c=0.50 id=36% cov=89%
-EKAMVLFSGGVDSTTCLGLAIEKYgvQNVIPLSVQYGQKHEKEVEAARRILEYYGIEGME-LDLTPIfaySDCSLLSHSEKEIPEASYAEqlrENEGVPvSTYVPFRNGLFLACAASIALSRECSCIYYGAHRDDAAGsaYPDCSESFFESMNRAVYEGSGQQIRIEAPFIKMNKAQIVAEGL---RLKVPYEFTWSCYEG-KEKPCGVCGTCIDRSEAFK--------------------
>UniRef50_A9A531(1-207:224) ExsB family protein n=2 Tax=Thaumarchaeota RepID=A9A531_NITMS   E=6e-22 s/c=0.51 id=39% cov=85%
MKKAVVVFSGGVDS-VCAVSFLKSKYELYGITFSYGQKANMEISATKSFAKKLGLKQHKIIDIGFMKELYGDSnvLTSSKRKIPSkFE------YSIVVPIRNAVFLSVASAWAYTLNASLVVYGAHTGD-KYYPDCRPAFAKKLESAFNQgeidGINSKIRKKIKI-WSPYREGLSKSDLLKKGKKVLGDsifrTWSCYSN-KKLHCGVCESCNNR-------------------------
>UniRef50_O29807(2-211:239) 7-cyano-7-deazaguanine synthase n=1 Tax=Archaeoglobus fulgidus RepID=QUEC_ARCFU  E=1e-21 s/c=0.50 id=38% cov=86%
--KAVMLLSGGIDSSTLLYYLLDGGYEVHALTFFYGQKHSKEIESAEKVAKAAKVRHLKVDISTIHDLISYGALTgEEEVPKAFYSEEVQ--RRTIVPNRNMILLSIAAGYAVKIGAKEVHYAAHLSDYSIYPDCRKEFVKALDTAVYLAnIWTPVEVRAPFVDMTKADIVRLG---LKLGVPYELTWSCYEG--GDrPCLSCGTCLER-------------------------
>UniRef50_Q8U4N3(3-235:240) 7-cyano-7-deazaguanine synthase n=3 Tax=Pyrococcus RepID=QUEC_PYRFU   E=5e-21 s/c=0.44 id=34% cov=94%
-RRAVVLFSGGLDSTACLYWAKKQYDEVIMLTVNYGsNEERVTNKVAEYFSKELDVRL-KIVKLDFLKEFSEirgSSLVGGEVPrvtaeeLEDIEKASETARSVWIPARNLVLISVAASLLDALGGGDIIVGFNAEEATTFPDNSREFVEKLNEALRFATLNPVKVVAPLIDLDKR---GIAKLLKELNAKYEYSNSCYNpkGFTEDGrpihCGECESCVRRHKGLIEGIGEDKTVYA---------
>UniRef50_B3T674(10-216:233) Putative ExsB n=1 Tax=uncultured marine crenarchaeote HF4000_ANIW141O9 RepID=B3T674_9ARCH  E=2e-19 s/c=0.47 id=35% cov=86%
MKKAVVVFSGGIDSVSTCTYLKQKY-ELYGISFLYGQKANQEIKKAKSFAKILGLKEHKVVDINFMKKLYgdTNALTSSKKKIP-----SKFNYSVVVPIRNGIFLSIATAWAFSINASLVAYGAHMGD-KNYPDCRPAFSKKIEFAfnqgeidgIKSGIRKRIQIWSPYKAKLSKKQLLKKGYDTLGDKIFN-TWSCYKNGKVQ-CGKCESCNNR-------------------------
>UniRef50_D2RLP8(3-220:232) ExsB protein n=3 Tax=Bacteria RepID=D2RLP8_ACIFE   E=8e-16 s/c=0.40 id=35% cov=88%
-KKALVLSSGGVDSTTCVSVAVEEFgkENVSTVSIFYGQKHRKELECARKVAEYYG-LPHYELDLSKIFQYSNCSLldhSTEEIVHESYEQQiaenGEGKVSTYVPFRNGLMLSAVASLAmsiYEKDDVSIFIGAHADDAAGnaYADCSEAFIGAMGKAISLGTYNQCHIVAPFASCSKAGVVKRGlELHTPYDL----TWSCYEG--GDKpCGTCGTCIDRARAF---------------------
>UniRef50_C0WAE7(3-220:233) Archaeosine biosynthesis protein queC n=3 Tax=Bacteria RepID=C0WAE7_9FIRM  E=2e-13 s/c=0.36 id=33% cov=88%
-KKALVLSSGGVDSTTCVSVAVHELgrENVATVSIFYGQKHRKELDAAQKVA-DFYHVPHYELDLSKIFQYSNCSLlshSTEEIIHESYEDQiaqnGEGKVSTYVPFRNGLMLSAVASLAmslFEKDDVDIYLGAHADDAAGnaYADCSEAFTDAMGKAISIGTYEQCHLVAPFVEVNKA---GIVKKGLELGTPYELTWSCYEG--GDrPCGTCGTCIDRARAF---------------------
>UniRef50_A0B6A6(1-220:224) 7-cyano-7-deazaguanine synthase n=4 Tax=Archaea RepID=QUEC_METTP   E=7e-13 s/c=0.35 id=32% cov=92%
MGRAVCLCSGGLDSTVAATIARRSGMDVYLIHVSYGQQaERREIEAIERIADAIGASDLMCSRIDLFRN--ISALTTQGARIPRGEEvslDSESTPPTWVYCRNTVLLSMAAAYAEYLGAHSIYVGFNAEEAMSYPDNRPEFVEQFNALLEKAVAsfsRPPKVVAPLVDMRKKDIVRLgADIKAPLEL----TWSCY--LNGEiHCGTCESCQHRRRGFVEAGIPDPT------------
>UniRef50_Q0W7U0(1-219:222) Succinoglycan biosynthesis regulator n=1 Tax=uncultured methanogenic archaeon RC-I RepID=Q0W7U0_UNCMA  E=9e-13 s/c=0.35 id=29% cov=90%
------MLSSGLDSVVAFKKEHDEHGVALAITFDYGQRAASkEIEMARQICARYHVR-HEVIELPWLKQITRTALVSRQAEVPEpTEAELDEIKGraletahlVWVPNRNGAFINIAAAFGDAYGYNRIVCGFNAEEGATFPDNTPAYVDAVNKSLALSCEKQVQVVAPVIHFDKEEIIREGvRIEAPLDL----SWSCY--FAGEKpCGKCESCMRRARAFKRAGVPDPS------------
>UniRef50_A8AAU7(4-228:260) ExsB protein n=1 Tax=Ignicoccus hospitalis KIN4/I RepID=A8AAU7_IGNH4  E=1e-11 s/c=0.32 id=38% cov=85%
----VGLVSGGMDSATAFADAINKFnpDVKVALTVVYGQRHARELKAAAEVAKFYGAQ-HLVVDLSdLFEKVKEVSALLGGRGVPEAEELVPGlVPPTYVPQRNAVLLASAGAILEKLMIErndglgVISVGFHGTDYAPgepvYPDTRPEFVEAMERALNEGSSVVFNFKragreakitiyAPFVRLKKKDVVKRALELGvPLEL----TWTCYRG--GDrPCGTCPACvsRLRA------------------------
>UniRef50_C3XFP7(3-194:213) Queuosine biosynthesis protein queC n=1 Tax=Helicobacter bilis ATCC 43879 RepID=C3XFP7_9HELI  E=5e-11 s/c=0.37 id=32% cov=82%
----LVLFSGGVDSTTALFWSKKEC-ATHALIFKYPSLHnKREIDAAVQIC-KDENVSYTLLDMSSVFVGFRSALlqnSSESIPQDSYNLES--MAKLVVPFRNGIFLSVAAGLAESLGYKEIVLANHAGDHPLYPDCTQSFIDSMNESIMQGSGGAVKLCSPFCNWDKKEIVKLGLSLG-VDYTK--TYSCYRG----GEKHCNTC----------------------------
>UniRef50_Q981C9(243-446:464) 7-cyano-7-deazaguanine synthase n=13 Tax=Thermoprotei RepID=QUEC_SULSO  E=1e-08 s/c=0.31 id=29% cov=85%
--RVLVVASGGLDSTVAATKLLREGHEVTLIHFNY--HHKAE-EKEREAVRKIAEYLQIPLleiNTDLFKIIGHATLIKGGGEIVKDRKGEEGaeFAHEWVPARNLIFFSVSLAIAEAYGYDAIASGINLEEAGAYPDNEMEFIRMLNKlsPYATGPNKRIEILMPVGNLVKHEIVKLGYEIGaPLHL----TWSCYEGGQKH-CGKCGPCYMR-------------------------
>UniRef50_Q8ZVX7(8-231:269) 7-cyano-7-deazaguanine synthase n=7 Tax=Thermoprotei RepID=QUEC_PYRAE  E=4e-06 s/c=0.24 id=33% cov=86%
--RVVAVVSGGPDSTCYTALWLKRGCDVHALSFLYGQKAVVEVERAQLLLRRLDGIAaergwgrvveHRVVDLSSLGELWRGTQLTD----PSVSVEQSYTPTVVVPIRNVVMAAVATAYAYTVGRNAgaktyVILGSHYDDIKPredtweplYPDCSPECVEAMQTAFRICHFRGERGVE--IWTPSREglrkSQLLKMCHQEVGDLIYDTWSCYKSGEAH-CGSCESCKNR-------------------------
>UniRef50_Q24ZT5(5-204:220) 7-cyano-7-deazaguanine synthase 1 n=1 Tax=Desulfitobacterium hafniense Y51 RepID=QUEC1_DESHY  E=4e-06 s/c=0.27 id=24% cov=86%
--KVVLLFSGGIDSTVLLFWLLSRNYEIFPLFINYGQKsYEGELEAINKILKDLNTKNNLLtLNMPELQLVGSGALVGE-YP-KNISSHNEWYASEFFPNRNMILLSIAATYGYKLQISKIAIGVVG---DSYQDTTRTFLEAMEMTLAQSIA---RYELIAPFAGHPRQKVIEEAY-RLQVPLKSTFSC-NAMGNRHCLLCTSCYEREKAI---------------------
>UniRef50_Q13AQ3(3-204:206) ExsB n=6 Tax=Proteobacteria RepID=Q13AQ3_RHOPS   E=3e-05 s/c=0.25 id=27% cov=86%
---ALLLCSGGLDSTTVGYWLVEKNISFQPLFFDYGQHcVEKEWETLQEV-LPISGLVSPLLRIN-ISEIFQHSPSR-LIAEPNLWTEHVEDDDLYIPYRTLMFFSVGACIAQTRGLDAVYAGFINSNHAKELDCSAAFLNNLDSlSRSLG---PVRFELPF------RDWSKADVVRRANELRvpvGKTYSC-QLFSDTPCGACPNCVERISAIESF------------------
>UniRef50_A8GPK3(1-226:227) 7-cyano-7-deazaguanine synthase n=18 Tax=Proteobacteria RepID=QUEC_RICAH  E=8e-76 s/c=1.26 id=35% cov=93%
MKKAVMLVSGGADSATVLAMAREIGYEIHSMSFNYGQRNNAELRKVKELIKEYNVKQHKIVDID-LRAFGGSALTDDNIDVPHYHDVNavpEDVPVTYVPSRNTIFLSYALGYAEVIGAKDIFIGVHTSDSANYPDCRPEYIKSFEKMANLATsigiqGQKITIHTPLIDMTKEQIIRTGL---KLGVDYKNTISCYEPTEDDsSCGNCLACMIRLDAFKKNNIQDP-------------
>UniRef50_Q55468(3-217:232) 7-cyano-7-deazaguanine synthase n=43 Tax=Bacteria RepID=QUEC_SYNY3   E=1e-73 s/c=1.29 id=36% cov=90%
-KTAVVLLSGGLDSATVAAIAKREGYRVIALSFNYGQRHDRELRAAADIVQALGIPEHFSINLD-LAQWGGSSLTDRQQTLPQTGVEPDIIPSTYVPGRNTVFIALGLSLAEAKGAEAVFLGINAIDYSGYPDCRPEYLATYQQLAALSSkvgveGRPIQLLAPLIELSKVDIVHKAL---ELGVPIAQTWSCYAGGE-EPCGRCDSCRLRDQALIE-------------------
>UniRef50_A6VQW6(10-227:235) 7-cyano-7-deazaguanine synthase n=22 Tax=Pasteurellaceae RepID=QUEC_ACTSZ  E=2e-73 s/c=1.27 id=49% cov=94%
-RKAVVIFSGGQDSTTCLLQAIRDYgpNNVEAVTFQYGQRHAIELQKAQWIAQDLGVKQ-TLIDTSVIKTITTNAMMSDA----QIKQDENGMPNTFVDGRNALFLLYAAIYAKGQGITDIITGVCETDFSGYPDCRNVFIKSMNVTLNLAMDYQFNIRTPLMYLTKAQTWQLADELGALDYVRQYTHTCYLGVEG-GCGTCPSCLLREKGLKQYLAQKSAVEKS--------
>UniRef50_B9Z9V1(24-242:251) ExsB protein n=2 Tax=Halobacteriaceae RepID=B9Z9V1_NATMA   E=6e-73 s/c=1.26 id=35% cov=94%
--RAVVLLSGGMDSATAAAEARSQGYDIYALHTSYGQRTEtRELECARQLADEFEANDFLQIETGHLSAIGASSLTDDEMAVADADMDSDEIPSSYVPFRNANLLAMAVSYAEANDCEAVFIGAHSEDFSGYPDCRPEFFEAFERVADVGTkpETEISIEAPFVEWSKTDI---AAHGTELGVPYEHTWSCYRDDQ-PACGTCDACAYRLQAFQRIGVRDPIEYA---------
>UniRef50_O29807(2-213:239) 7-cyano-7-deazaguanine synthase n=1 Tax=Archaeoglobus fulgidus RepID=QUEC_ARCFU  E=3e-72 s/c=1.29 id=34% cov=92%
--KAVMLLSGGIDSSTLLYYLLDGGYEVHALTFFYGQKHSKEIESAEKVAKAAKVR-HLKVDISTIHDLISYGALTGEEEVPKAFYSEEVQRRTIVPNRNMILLSIAAGYAVKIGAKEVHYAAHLSDYSIYPDCRKEFVKALDTAVYLAnIWTPVEVRAPFVDMTKADIVRLGL---KLGVPYELTWSCYEGG-DRPCLSCGTCLERTEAFLANGVKDP-------------
>UniRef50_D0MDN1(17-233:238) ExsB protein n=1 Tax=Rhodothermus marinus DSM 4252 RepID=D0MDN1_RHOM4  E=3e-72 s/c=1.26 id=46% cov=92%
-ETALVLLSGGQDSTTCLYWALHYFPKVEALGFHYGQKHAVELEQARKIADRAGV-PFTVLDLRGL--LRGSALTEHEQDVSAAHPLAPHLPAAFVPGRNALFLTLAASYGFTRGIHDLVGGMCQTDYSGYPDCRREFIDAMERALSLALDTPIRIHTPLMHLTKAETWRLARELGILDVIVELTHTDYNGDRSErhpwGYGRLdnPASILRARGYEEAKA----------------
>UniRef50_C0QST3(1-221:227) 7-cyano-7-deazaguanine synthase n=7 Tax=Aquificales RepID=QUEC_PERMH  E=3e-70 s/c=1.21 id=36% cov=92%
MKQSssiIILVSGGMDSAALLWLAKKEFDKVYAVSFDYGQKHRVELDFAKKLTEEAGVEEHFIAEVPHLKGIKGSALTDRSVEIPSEEY-PEGPPVTTVPMRNLNFLSIAASFADIYEIENIGIGVHSVD-SPYPDCRAEFVSAAEAAINASSvmvakkKNRITVYTPFLGMTKTDVLRIGL---ELGVPYEKTYSCYRGTI-PPCGECATCRQRIEAFRSVGLEDP-------------
>UniRef50_Q7NCE2(1-223:234) 7-cyano-7-deazaguanine synthase n=2 Tax=Bacteria RepID=QUEC_GLOVI   E=6e-70 s/c=1.19 id=47% cov=94%
MKKALVVFSGGQDSTTCAALACREYDEVHAVTFEYNQRHAIELESARAVGQALGLTGHEFIRLGPL--LKGTSPLVSDAPLGQYASAAElpaGVEPTFVPGRNILFLTLAANRAFCLGTGDIVIGVCEADFAGYWDCRQVFVEAMARALGEGIYGDanaIRIHTPLMRLTKAETVKLSVEVLgeRFEEVLALSHTCYAGVRG-GCGRCHACILRDRGFREAGVPDP-------------
>UniRef50_A6UV33(2-232:234) 7-cyano-7-deazaguanine synthase n=12 Tax=Methanococcales RepID=QUEC_META3  E=1e-67 s/c=1.12 id=29% cov=95%
--KAVCVLSGGLDSAVCMAMAKSEGLELYSITFDYGQRAvKKEIIASKKLSELFGAV-HKVVELPFVKDFSSSALTKKEEEVPtiknseldNLEKATETMEKVWVPARNMILFSISSGFAEFVDAKYIYTGLNVEEGATFPDNTEEFLNRFNSVLEYGTLNKVKMKSPLYKYSKKEIVKIGKKLEEkLNVEFlKYSYSCYHDNKTDflHCGTCESCMRRKRAFKEAGVEDPTEY----------
>UniRef50_C4Z7K4(2-226:227) Queuosine biosynthesis protein QueC n=5 Tax=Bacteria RepID=C4Z7K4_EUBE2  E=2e-67 s/c=1.14 id=33% cov=93%
--KALVLSSGGVDSTTALALAVSRYgkDNVIALSVSYGQKHDKEIQAAKAVSAFYGVEQ-LFLDLSKIFQYSNCSLlqqSTEEIPEESYarqieKTEGEKPVSTYVPFRNGLFLSSAASIALSKDCSVILYGAHADDSAGfaYPDCSPMFNDAMNQAIFEGSGHQLKVEAPFVNMTKAEVVKMGL---ELNAPYELTWSCYEG-KDVPCGKCGTCIDRAAAFAANGVSDPAI-----------
>UniRef50_Q857D1(4-223:235) Gp3 n=2 Tax=unclassified Siphoviridae RepID=Q857D1_9CAUD   E=4e-64 s/c=1.12 id=34% cov=94%
FRSPLVLLSGGMDSSTLLAWALDRpdVDQASALFVDYGQRHVVERASSQLVAQHYGAAWSE-LDLRAFGASVNSALTVMAREVPHGHYAEDNMVQTVVPNRNATLISAAAGIAASLGHDAVLTAVHVGDHAVYPDCRPEFVAAIDMATFAGCG--VHVVAPFQTGDKADIARLG---GQLGVPYHLTWSCYEGGlnDARHCGRCGTCVERAEAFAEAGVPDPTEYA---------
>UniRef50_Q8UAM7(2-217:236) 7-cyano-7-deazaguanine synthase n=71 Tax=Alphaproteobacteria RepID=QUEC_AGRT5  E=3e-62 s/c=1.11 id=34% cov=93%
--KTIVICSGGLDSVSLAHKIAAEHELLALVSFDYGQRHKKELDFAADCAKRLGV-PHHLIDIGTIGAhLTGSALTDD-IDVPDGHYAEETMRSTVVPNRNAIMLTIAFGLAAAQQADAVAIAVHGGDHFIYPDCRPGFIGSFNamQAHALEGYADVTLFAPYVTVSKAAIVTDAVKYGT---PFGETWSCYKGGL-RHCGRCGTCVERREAFHLAGVTDPTEY----------
>UniRef50_A8AAU7(4-242:260) ExsB protein n=1 Tax=Ignicoccus hospitalis KIN4/I RepID=A8AAU7_IGNH4  E=4e-60 s/c=0.97 id=33% cov=91%
----VGLVSGGMDSATAFADAINKFnpDVKVALTVVYGQRHARELKAAAEVAKFYGA-QHLVVDLSDLFEKVKevSALLGGRG-VPEAEELVPGLvPPTYVPQRNAVLLASAGAILEKLmierndGLGVISVGFHGTDYAPgepvYPDTRPEFVEAMERALNEGSsvvfnfkragrEAKITIYAPFVRLKKKDVVKRAL---ELGVPLELTWTCYRGG-DRPCGTCPACVSRLRAFMEAGVPDPLT-----------
>UniRef50_C3XFP7(3-209:213) Queuosine biosynthesis protein queC n=1 Tax=Helicobacter bilis ATCC 43879 RepID=C3XFP7_9HELI  E=2e-58 s/c=1.10 id=27% cov=87%
----LVLFSGGVDSTTALFWSKKE-CATHALIFKYPSLHnKREIDAAVQICKDENV-SYTLLDMSSVFVGFRSALLQNSSEsIPQDSYNLESMAKLVVPFRNGIFLSVAAGLAESLGYKEIVLANHAGDHPLYPDCTQSFIDSMNESIMQGSGGAVKLCSPFCNWDKKEIVKLGLS---LGVDYTKTYSCYRGGEKH-CNTCPTCIESNESF---------------------
>UniRef50_UPI00016988F1(5-164:213) exsB protein n=1 Tax=Endoriftia persephone 'Hot96_1+Hot96_2' RepID=UPI00016988F1  E=3e-57 s/c=1.40 id=46% cov=68%
-KRAVVLLSGGLDSATVLAMARQQGFECHALSMLYGQRHAAELDAARQVAQALGAVDHKLINIG-LDDIGGSALTDEQIAVP--KTPSEGIPPTYVPARNTVFLSLALGWAEVLEAQDIFIGVNAVDYSGYPDCRPEFIVAFEQLANLATkagveGRRIHIHTP------------------------------------------------------------------------
>UniRef50_Q96ZD9(2-201:202) 7-cyano-7-deazaguanine synthase 1 n=1 Tax=Sulfolobus tokodaii RepID=QUEC1_SULTO  E=2e-45 s/c=0.92 id=26% cov=87%
--KALLLMSGGLDSSSAAYYYTRRGLDFDCLFINYGQRsARMQLRSSKIICEKLN-KKLLVADIRKIRELFIS-----DIWLKPHEP---------ITHRNLVIIPIAIAFAKEKGYEEIIIASVKEDCE-YEQNRIEIIKELK---NLGEILKVKVSTPFAGMPKSFLLKLGVSAG---LDPSLTYSCLLGHKYH-CGQCSQCLKRKEAFKSANIQDPTKYLNL-------
>UniRef50_Q24ZT5(5-205:220) 7-cyano-7-deazaguanine synthase 1 n=1 Tax=Desulfitobacterium hafniense Y51 RepID=QUEC1_DESHY  E=1e-44 s/c=0.90 id=23% cov=86%
--KVVLLFSGGIDSTVLLFWLLSRNYEIFPLFINYGQKsYEGELEAINKILKDLNTKNNLLtLNMPELQLVGSGALVGEYP--KNISSHNEWYASEFFPNRNMILLSIAATYGYKLQISKIAIGVVGD---SYQDTTRTFLEAMEMTLAQSIARY-ELIAPFAGHPRQKVIEEAY---RLQVPLKSTFSC-NAMGNRHCLLCTSCYEREKAI---------------------
>UniRef50_A8V022(2-163:166) Trans-regulatory protein ExsB n=1 Tax=Hydrogenivirga sp. 128-5-R1-1 RepID=A8V022_9AQUI  E=8e-43 s/c=1.09 id=30% cov=68%
------------------------------------------------------------VDIPHLKGIEGSALTDEKVDIPSEDY-PDQPPITTVPMRNLNFLSIAASFCDVYEIENIGIGIHSVD-SPYPDCRAEFASSAEAVINASSvmvakkKNRIKVYTPFLGMTKTDVLKLGL---ELGVPYEKTYSCYRGTI-PPCGECATCRQRQEAFESVGVKDPLVKA---------
>UniRef50_B7GTM4(7-226:251) ExsB family protein n=2 Tax=Actinobacteridae RepID=B7GTM4_BIFLI   E=1e-29 s/c=0.60 id=23% cov=90%
--RVALLLSGGPDSTTLLYDLLNQGKEIYAVTFNFGETEGcNESQHAQRIVTNLHSERLHHYQYDFSEQF------KRFYELPQPQFLRKAFGPFVVapnkeehvqPFGSAIALMLMASWALKHDIVDVYYAVHSND-AVFHDNHASYFEALHTVTVecEGDEYGVTFHTPYLSINKCAVIQKG---MGLGVPFGDTWSCALGGTVH-CGVCDPCRDRRTSFEILGIKDPVLY----------
>UniRef50_D2L9Z8(3-185:201) ExsB family protein n=1 Tax=Desulfovibrio sp. FW1012B RepID=D2L9Z8_9DELT  E=3e-27 s/c=0.68 id=29% cov=78%
-KNSAILLSGGMDSTSLAFWKKPNF----AFTIDYGQKAAMaEIRAARQVAKEIGI-SHDTIAIDC------SSLGSGDMAMAAPLP---NAPSTdWWPFRNQLLITLAAMKAICRNINLLYIGLVKSDSS-YKDgCS-DFVDKISRTLSF-QEGNIEVMAPAIDMTAAELVNMSKIPRTL---LAWSHSCH--VSDFACGRCRGC----------------------------
>UniRef50_Q0BZ62(10-184:188) Putative uncharacterized protein n=1 Tax=Hyphomonas neptunium ATCC 15444 RepID=Q0BZ62_HYPNA  E=2e-26 s/c=0.69 id=27% cov=76%
----VVLVSGGIDSAACAAMYANNGGSTTGVFVDYGHPAAIeEFASAEKVCAALGIP------------LLKTSFSTDRITGPGE-----------IVGRNALLI-WSAVFASGIKKGVIAIGVHAG--TTYYDCSSTFITRMDNMLAESTNGLVRISAPFVNASKSEVFS---YLQRSKVEASLTYSC-ESGSKEPCGICASCQDRTK-----------------------
>UniRef50_Q12C85(32-254:282) ExsB n=1 Tax=Polaromonas sp. JS666 RepID=Q12C85_POLSJ   E=4e-24 s/c=0.51 id=25% cov=92%
--KAIVVFSGGPDSLAAALWAKSKKYDPWLLTFQFKQREQgGEMFASMLLAKTLGF-PQEIIDFKSPMHSFEptvhvlmHAGTTTTADRAQHHRMEFGA---------GMVMATACTFAVYHQIDDVVWGATKDDVFGgrfeY---SQEFADAFANLVSCTTGRPFRIHVPFASKSKHQV--LAEFSGKEDL-FAMSWSCKVGSSIQ-CGTCTACVARRVAAQASGVKDATSYHEQNYKSPL-
>UniRef50_B4U7S9(2-190:196) ExsB family protein n=1 Tax=Hydrogenobaculum sp. Y04AAS1 RepID=B4U7S9_HYDS0  E=3e-17 s/c=0.48 id=21% cov=79%
--KVVSLVSSGFDSISLLNYYINKNYEIYPIYVKSGFKwEEEELKHLKDIIDHISKSYKLIKPLkvshapnDFFEDFNERAFINDE--------------DVEIPFRNLDLLISALKYAYAVDANLIAIGIMGL--VAFKDNSYNFIKTINDLFS--MYGDYKVDTPFLGMSKKDVFDR-YFIKEL---FDKAFCCMNPTDGKECGVCSKCKE--------------------------
>UniRef50_C5PNW4(8-191:198) ExsB superfamily protein n=1 Tax=Sphingobacterium spiritivorum ATCC 33861 RepID=C5PNW4_9SPHI  E=1e-14 s/c=0.45 id=26% cov=77%
-----LLLSGGVDSICLAYGLKPD----IAYTINYGQiPASREIYVSRYICNLLRI-QHKVIEVNC-KSLGSGILINEER--LDISPSQE-----WWPYRNQLLITLAAMQAIKDKIGVLHLASVKSD-SFHKDGTPQFYDLINELVKY-QEGNISIVCESTGYYSHELVK------KYNVPLEIIafaHSCH--ISNTACGQCPGCK---------------------------
>UniRef50_B8JF98(142-357:447) PP-loop superfamily ATPase-like protein n=1 Tax=Anaeromyxobacter dehalogenans 2CP-1 RepID=B8JF98_ANAD2  E=4e-14 s/c=0.37 id=21% cov=85%
----VGLFSGGLDSIVGTYLRSRTAKKLIVVSV-----HGIQVRASAQ---------QRAITMLQRASFFSVPLhwVSFDHQLRHAHPPEKSQR-----CRGFLFLSIGAAVARTVGASTLHTyenGIGALNPPmnlaqvGAQNTRamhPGTLASLEGILEVVQDDPVRLEAPFLFSTKGEMCRDAREHL---IPLAQaSNSCDEGEHGKPdpaehCGLCTSCLLRRSAlFAALGDKDPTPY----------
>UniRef50_Q9RZH7(140-350:423) Putative uncharacterized protein n=1 Tax=Deinococcus radiodurans RepID=Q9RZH7_DEIRA  E=2e-12 s/c=0.36 id=23% cov=83%
----VALLSGGLDSLVGMIDLVAEGHNPLAVS----QLVAGDAAKQREIATDLGRTTHLQLN--------------HAAECPT--PGEDSQRS-----RTLIFLAYAvlAATATTRfqQARAvpIYInenGFIALNPPLTPmrigslSTRtahPVFLQQLQAVL-QAVGLNVALINPYALKTKGEMLTECANQTVLSRWASATTSCgrYRRFGYKHCGRCIPCQVRRAAFLAWGQPDRTEY----------
>UniRef50_A8L9C0(132-315:372) ExsB family protein n=2 Tax=Actinomycetales RepID=A8L9C0_FRASN   E=4e-12 s/c=0.40 id=26% cov=72%
----VLLFSAGLDS----FPAWHYLGKPPALYFDLGHRYRdQERAAITALVDRCGIKvtVSQELDLSQWEA-------DDAI----------------IPLRNVYLAMLAANRAERIWCVGV-----KGDATA--DKSPQAFHQISQMITDLSGRPVWLDSPFWQMTKTEIVAwyLGQGLPAGDLL--LTFSCSRTDSAmTHCGQCPSCLRR-------------------------
>UniRef50_A3CVZ1(17-160:257) ExsB family protein n=1 Tax=Methanoculleus marisnigri JR1 RepID=A3CVZ1_METMJ  E=1e-11 s/c=0.50 id=26% cov=62%
---VAVALSGGTDSSVLLALARHHGIQVIAISVDTGLTPPGELAAARKLSERLGL-PHVVIPLDML-------------DIPAVRENRPD--RCYVCKR-AMMEAI-VAEARRQGCRTVVDGTHADD-------RPAARPGMRVLSELG------IKSPFAEcgMGKADVEALARELG-------------------------------------------------------
>UniRef50_Q4UTY2(141-355:428) Putative uncharacterized protein n=2 Tax=Gammaproteobacteria RepID=Q4UTY2_XANC8  E=2e-09 s/c=0.30 id=23% cov=84%
-EDSVCLLSGGMDSLIGAIDLAESGRRSIAVS---------------NTVPGDGHNQHSFAEAVGFKHL---PLNHNASPPSDGSREPSQR------ARSIIFLAFgvlaATSLqAYQDGAQVpLFIcenGFIALNPPltgtrlGSLSTRtahPEFLHGVQSVLDAA-GLRVNLINPYQHKTKGE---MSRECADQDLLRNLaasSVSCgrYRRYGYNQCGRCIPCQIRRSAYLAWGQPDPTDY----------
>UniRef50_Q3JDB4(141-354:425) Putative uncharacterized protein n=1 Tax=Nitrosococcus oceani ATCC 19707 RepID=Q3JDB4_NITOC  E=6e-09 s/c=0.30 id=20% cov=83%
----VTLLSGGLDSFVGAIDLVADGKAPFAVS----QVAAGDKQSQADFAAKIgGGLNHLQLN--------------HNVKCPGENERSQR-------ARSFIFLAYGvlAASAQKHYHDgervDLYIcenGLISINPPLTParlgslSTRtthPVFLGLFQRLLDVA-ELRIAVRNPYQFRTKGEMLLECKDQAFLRKHAAETTSCgrYARNGWQHCGRCFPCLIRRAAFHAWGKDDRTKY----------
>UniRef50_B2IBH3(31-222:431) tRNA-specific 2-thiouridylase mnmA n=141 Tax=root RepID=MNMA_BEII9   E=1e-08 s/c=0.33 id=26% cov=67%
--RVVVAMSGGVDSSVVAALLKREGYEVIGVTlqlYDHGEAvHRKgaccagqDIQDARQVADQLGI-PHYVLDyeerfrrkvIDPFAQ----SYATGETPIPCVSCNSE--------------IKFADLFetAQHLGADVLATG-HYVSSKAEADGGRALYRSLDSSRDQSyflfatTNAQLELLRfPLGDLAKPDVRQMARQLG-------------------------------------------------------
>UniRef50_B2A8M8(185-354:413) Probable tRNA sulfurtransferase n=2 Tax=Clostridia RepID=THII_NATTJ   E=1e-08 s/c=0.37 id=22% cov=68%
--KGVLMLSGGIDSPVAGWLAMKRGIQVVGLHFHsYpftSQRALKKVEDISQVLSRYGTGP-----TGGFKLITNH-FTDIQKAIQN--YCSESMWVTV--MRRFMFY-IANRMAQKEQAMTVVTGENVGQVAS------QTLESM-HAVSQ-DVVNLPILRPLAGLDKKEIMSKAETIG-------------------------------------------------------
>UniRef50_D2MP56(177-341:472) Thiamine biosynthesis/tRNA modification protein ThiI n=1 Tax=Bulleidia extructa W1219 RepID=D2MP56_9FIRM  E=2e-08 s/c=0.38 id=23% cov=68%
--KVMMLLSGGIDSPVATYQLIKRGLKVEAVHFAappYTSEAakNKVLKLASMISDYQGGMKVHVVPFTELQ-------------LDIYRVAKDPYAITL--MRRMMF-RIAEKLAINNRCLAIGTGESLGQVAS---------QTLESMVTINDVVHIPVLRPLVSMDKVEIIQLAREIGTYEtsiLPYED-----------------------------------------------
>UniRef50_O29382(167-331:374) Probable tRNA sulfurtransferase n=2 Tax=Archaeoglobaceae RepID=THII_ARCFU  E=3e-08 s/c=0.37 id=28% cov=62%
--KVVALISGGIDSPVAAFMAMKRGCEVVAVHFF-NQtmHSPKVREKIRMLAEKLAEYQGKI----------------KLYMVPFKEVQFEIINRVppklrmVVYRRSMM--RMANLIAEKEGCKAVVTGDSLSQVAS------QTLDNINVIYS---ASKLAVLPPLIGMDKEEIVAIAK----------------------------------------------------------
>UniRef50_Q65G52(179-343:401) Probable tRNA sulfurtransferase n=20 Tax=Bacillales RepID=THII_BACLD  E=5e-08 s/c=0.36 id=23% cov=64%
--KAMLMISGGIDSPVAGFYAMKRGLEIEAVHFFsppYTSERAKQkvIDLTKRLTAFGGDIKLHIVPF-----------TKTQELIQKQIPENYSMTAT---RR--LMLQIADKLRERHNALAIFTGESLGQVAS---------QTLESMYAINAVTSTPVLRPLIGMDKTEIIEKAKE---------------------------------------------------------
>UniRef50_Q9ZJQ0(2-177:342) tRNA-specific 2-thiouridylase mnmA n=22 Tax=Campylobacterales RepID=MNMA_HELPJ  E=5e-08 s/c=0.34 id=32% cov=25%
--KIAVLLSGGVDSSYSAYSLKEQGHELVGI---YLKLHASEkkhdlyIKNAQKACEFLGI-PLEVLD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A4T1U6(144-374:454) Putative uncharacterized protein n=2 Tax=Actinomycetales RepID=A4T1U6_MYCGI  E=6e-08 s/c=0.26 id=24% cov=82%
---AVSLFSGGLDSLTGVIDLLEEDPDrrLCLISHNEGdQASTAQKTLTAALREHYGQDR---LELRSLFLRPAPAVAGQARPLPPERETTTR-------ARSLLFLTAGLALAASVGPDvpvYIpengFIGINvpltrarSGSYST----RtthPQFMQLLRTAAdAVGVCNP--ILNPFRLKTKGEILASSRNPELLRSLAPNSISCshpeaarYAVRKQGNCGYCFPCLIRR------------------------
>UniRef50_B9L3Q7(182-336:407) Thiamine biosynthesis/tRNA modification protein ThiI n=2 Tax=Thermomicrobia (class) RepID=B9L3Q7_THERP  E=7e-08 s/c=0.39 id=26% cov=65%
--RVVALLSGGFDSPVAAYRLMKRGCFVTFVHFHaYPYVRPISIEKAVELARHLSrfqppKNRLIVVPIGDAQRVIALA------AEPSLR---------VVLYR-RLMLRIATAIAHEEGAGALVTGESLGQVAS---------QTLENMRAIGAVTDLPLLRPLVGNNKDEIIAEAVRIG-------------------------------------------------------
>UniRef50_C5A340(49-131:276) P-loop ATPase, MJ1599 type n=8 Tax=Thermococcaceae RepID=C5A340_THEGJ  E=7e-08 s/c=0.72 id=33% cov=34%
MKnvdKAIVAYSGGKDSVVALYLAKEVYKvpELEAVMIDHGLMAEEAIENARRIAEHLGV-PFRVLRYDY-SDIFRNALLKGQSP-------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B9QRC5(216-345:457) Putative uncharacterized protein n=1 Tax=Labrenzia alexandrii DFL-11 RepID=B9QRC5_9RHOB  E=9e-08 s/c=0.46 id=31% cov=33%
----------------------------------------------------------------------------------------------------------------------------------YPDYRnhPRFTQRMERLLKALFGKEIRYVFPRLWNTKGETLR-SFATLPEGSNWHTTRSCWRsnrwcsvNGKRRQCGVCAACMLRR------------------------
>UniRef50_Q9Y933(221-386:512) GMP synthase [glutamine-hydrolyzing] n=5 Tax=Archaea RepID=GUAA_AERPE  E=1e-07 s/c=0.36 id=26% cov=69%
---AVAAVSGGVDSTVAALIAKKAiGSRLYPVFIDHGLHPEGEVERVVKLLSRLGLEPVMV----DAGEEFLAALEGVGDPEEKRR----------VVGR--VYAEVLERAARDIGAEYLVQG------TIYPDviesgARPgaDTIKTHHNVGGLPKDMRLKLVEPLRYFYKDEVRLLAE---KLGVPRELIW---------------------------------------------
>UniRef50_Q6WHP6(7-174:228) Putative uncharacterized protein n=1 Tax=Vibrio phage KVP40 RepID=Q6WHP6_BPKV4  E=2e-07 s/c=0.35 id=23% cov=73%
----IILVS-GLDSLV-LYEFLERKP--HPVYFKWG-------FAIDDIEMAALPEETTIIEMPEILHL----------KHDPYEFKTPRNPDLI--GRNTLMFnSVFHAF----RPNVIYRGMLKGDDFYY-DASPTHSDEIAAMWSKMLNKECRIEQPFKDKTKRDIMQMAVEYGIDANSLQH---CYN--REHNCGRCSKCV---------------------------
>UniRef50_D0LKW7(32-179:296) Queuosine synthesis-like protein n=1 Tax=Haliangium ochraceum DSM 14365 RepID=D0LKW7_HALO1  E=2e-07 s/c=0.39 id=29% cov=61%
--RVLVAFSGGVDSAFLLKIASDElGADCHALTCVSVTMARSEVEDARALGDELGlAERHHVVESNELEQPGfadnpthRCALCKTE------------------------LMDVARPLAEQLGVEVIAIGTNIDDLG---DFRPGIAAAKERAARMPM-----VEA---GLSKADIRALSRQLG-------------------------------------------------------
>UniRef50_Q8TWX3(167-329:374) ATP pyrophosphatase involved in thiamine biosynthesis n=1 Tax=Methanopyrus kandleri RepID=Q8TWX3_METKA  E=5e-07 s/c=0.35 id=25% cov=69%
--RVVCLVSGGIDSPVAAWYAARRGCEVIWLHLDRG-KYGSEVDAVERLAGKFSEWLPSDVEL----------LIEDFEDFMESLEGLEGESARY---RCVLckreMIRRACDVCENVGAVAVVMGdVIGQVASQIPDN----LAVIDRVAR------FPVFRPLLGFDKNEVQRLSERLGLFEVSKEH-----------------------------------------------
>UniRef50_B0V938(149-366:442) Putative uncharacterized protein n=4 Tax=Acinetobacter baumannii RepID=B0V938_ACIBY  E=6e-07 s/c=0.26 id=25% cov=81%
--DSVCLFSGGLDSTIGAIDLKAQGKKSVLVSHAYPkdrqkQDHvyyDLQFDNARFQVL---ANPRKVKEIPadvqmrtrsfnfiAFGALIATALSKNhfsnkiiKLYIPENGLISINPPLT--PRR---------------------IGALSTRT-----THPYFLQKLNILFK-NIGLPVEIENPYQYKTKGEMMLECKDQSSLKKIAATTVSCGKWKRsGMQCGKCLPCLIRRASFDKYQYKDLTQY----------
>UniRef50_Q1GAV1(173-330:399) Thiamine biosynthesis protein ThiI n=10 Tax=Bacilli RepID=Q1GAV1_LACDA  E=6e-07 s/c=0.36 id=24% cov=66%
--KAVMMLSGGIDSPVASYLAMKRGVNIEMVHFFsppYTS--EKALAKAKEltsiLAKYSGRINFIEVPFAEIQE-------TIKEKLPEGYLMT-------VQRR--FMLRLADIIREKRHALAIFNGESVGQVAS---------QTLESMAAINNVTTTPVLRPVATMDKTEIIAKAEEIGTFDL---------------------------------------------------
>UniRef50_A3DEB6(181-345:392) Probable tRNA sulfurtransferase n=34 Tax=Bacteria RepID=THII_CLOTH   E=8e-07 s/c=0.34 id=23% cov=68%
--KAVLLLSGGIDSPVAGWMIAKRGVEIEAVHFYsypYTSERAKEkvIELTKILATYCQKINLHIVPFTEIQL---------EINEKCPHEELTII------MRRAMM-RIAEIIANKTGALALVTGESVGQVAS---------QTIQSLVVTNAVVSLPVFRPLIGMDKNEVVDIAKKIGTFEtsiLPYED-----------------------------------------------
>UniRef50_Q13XN6(248-358:458) Putative uncharacterized protein n=1 Tax=Burkholderia xenovorans LB400 RepID=Q13XN6_BURXL  E=9e-07 s/c=0.50 id=27% cov=44%
------------------------------------------------------------------------------------------------------------------------YGVYA-DYRNYP----TFFRKMERFIKALQGYQVRFEQPRLWFTKGQTLsAFLRIPGKSGEHLKSTRSCWQTrrvvnvGSRKQCGLCAACLLRRLSLHAAGVseaPDTYVVSDLAA-----
>UniRef50_Q5WAJ2(145-366:430) Putative uncharacterized protein n=4 Tax=Bacillus RepID=Q5WAJ2_BACSK  E=1e-06 s/c=0.25 id=17% cov=87%
--KKVCMFSGGLDSFIGAIELLDDTSENDTLFVsHYG--GGKGIKEYQDILREELISKYQLTESNFYSFYA------------SAKNGVEDTTRT----RSFMFFSHAVVLASSVDRpVNLVIpenGLISLNipltnsrlgSSSTRTTHPFYLSLFQKLLD-NLKIMVKILNPYQFKTKGEMIRECSSIEFLQKNITNTMSCSHPDWGRwagesevcHCGYCLPCVIRRSAIKNAGIQDETIY----------
>UniRef50_A8AA65(1-61:396) Argininosuccinate synthase n=5 Tax=Archaea RepID=ASSY_IGNH4   E=1e-06 s/c=0.91 id=37% cov=26%
MSKIVLAYSGGLDTSVAVAWLKEKFGaEVITVTVDVGQKEDfKEIE---ERAYKAGASKHYLID-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C5A5U2(21-81:262) Predicted ATPase of the PP-loop superfamily n=8 Tax=Thermococcaceae RepID=C5A5U2_THEGJ  E=2e-06 s/c=0.90 id=31% cov=27%
-KRILVLFSGGKDSSLTLYLLKEAGLDVSALTFFHRWSWHETLRWAMKFTRKLGVE-HYLVDI------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1UGP9(259-356:460) Putative uncharacterized protein n=1 Tax=Burkholderia sp. CCGE1001 RepID=D1UGP9_9BURK  E=2e-06 s/c=0.56 id=28% cov=32%
-------------------------------------------------------------------------------------------------------------------------------------CYPGFTKQLSRFLEKLTRKSIDFYHPALFQTKAQVLmQLEGHGVGLGQVLAQHWSCsYDSRWAHaehrkvHCGICGNCLLRR------------------------
>UniRef50_A0YNH9(158-374:488) Putative uncharacterized protein n=2 Tax=Oscillatoriales RepID=A0YNH9_9CYAN  E=3e-06 s/c=0.25 id=23% cov=84%
----VALWSGGLDALAGLYTRLQTSHTVPFMLFGTGSSksvYARQEKVFQAIIKSFPTHLYLCrVPINFL----NSKLLRKNKITR---------------ARGVVFTLLGAACAYLMGQRtlSVYengIGainlpyrasAVGLDHS-----RsvhPLTLLMVSDVVSELLGENFRVYNPFLFLTKAQICR-ALAENQENDLVAITQSCdsrhRKSQQPTQCGYCSSCILRKQALAASKIEDKTRY----------
>UniRef50_B7H703(180-344:404) Probable tRNA sulfurtransferase n=75 Tax=Bacteria RepID=THII_BACC4   E=5e-06 s/c=0.32 id=21% cov=65%
--KVMVLLSGGIDSPVAAYLTMKRGVSVEAVHFHsppfTSERAKqKVIDLAQELTKYCKRVTLHLVPFTEVQK-------TINKEIPsSYSMTVMRRMMMRITER----------IAEERNALAITTGESLGQVAS------QTLDSM-HTINEVTNYPV--IRPLITMDKLEIIKIAEEIG-------------------------------------------------------
>UniRef50_C7M0G9(1-179:341) tRNA(5-methylaminomethyl-2-thiouridylate)-methyl transferase n=1 Tax=Acidimicrobium ferrooxidans DSM 10331 RepID=C7M0G9_ACIFD  E=6e-06 s/c=0.30 id=27% cov=49%
MARVVVAMSGGVDSSVAALMAREAGHDVIGVTLrlteaagDRGCCSVGDVEDARTVAALLGI-NHIVAD---MRAEFHRAVVEPYLDaHRRGWTPNPCMScNRYVK------VTALAAWAQRLGASRLVTG-------------------------------------------------------------------------------------------------------------
>UniRef50_D2RUT9(1-62:429) Argininosuccinate synthase n=1 Tax=Haloterrigena turkmenica DSM 5511 RepID=D2RUT9_9EURY  E=8e-06 s/c=0.86 id=43% cov=26%
MTRVALAFSGGLDTTVCVPLLEEEygYDDVIGVTVDVGQPAS-EFEEAEETADALGLE-HYVVD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6Q239(3-181:339) tRNA-specific 2-thiouridylase mnmA n=2 Tax=Epsilonproteobacteria RepID=MNMA_NITSB  E=8e-06 s/c=0.29 id=31% cov=25%
-KKIVVAMSGGVDSSYTANLLQSRGYEVIGVYMKFHPReeyHQKNIANIQKVAKHLGIEYH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q12W34(18-177:267) ATPase of the PP-loop superfamily n=1 Tax=Methanococcoides burtonii DSM 6242 RepID=Q12W34_METBU  E=1e-05 s/c=0.33 id=25% cov=68%
-EKVLVAFSGGVDSSTlAALAFAALGDNALAVTLYSPMIPQSELEYAKRTAEVIGIK-HIVLDHDI--------LSDERIRINDPQRCYYCKKQ---------FVKKLKGVASEEGLNVIMEGTNASEITG----RRPGLEALREA-------GSSIFTPYVdfDVSKREVRQMASYLG-LDVANRPSNSC-------------------------------------------
>UniRef50_A8EUQ0(190-342:488) Thiamine biosynthesis protein ThiI n=4 Tax=Proteobacteria RepID=A8EUQ0_ARCB4  E=1e-05 s/c=0.34 id=22% cov=64%
---VISLMSGGFDSTVASYLTMKRGIKTHFIFFNLG-----------GLAHEIGVKQVAY----YLWNKFGSSHRVSFISVPFEDVVSQIFKDVSQPYMGVMLkrLMLLASekIADSLGIDALVTGESVAQVSS------------QTLRNLALIDQCTnklVLRPLSMMSKPDIIEIAQKIG-------------------------------------------------------
>UniRef50_A8ES35(4-180:345) tRNA-specific 2-thiouridylase mnmA 1 n=5 Tax=Epsilonproteobacteria RepID=MNMA1_ARCB4  E=2e-05 s/c=0.29 id=24% cov=70%
-KKVMVGMSGGIDSSVTAYMLQNEGYEVEGIYLKLHNRtdgyHEKNLGYIEDVAKFLNIK-YYILDLaDKFSkevyDYFVDSYLTGTTPNPCVKC-----------NRQIKFGAM-LDFAKQHGASYLATGHYAkTDGKFFyeaDDKTKDqsyFLSQVDKdALKYMMF-------PLSTYKKEDIVKFG---AKLDVAYKK-----------------------------------------------
>UniRef50_A1U6U9(179-333:484) tRNA sulfurtransferase n=11 Tax=Gammaproteobacteria RepID=THII_MARAV  E=2e-05 s/c=0.34 id=27% cov=64%
-ETVMTLISGGYDSSVAAYLMMRRGIRSHYLFFNLG-----------GAAHEVGVRQvaH------YLWERYGSSHNVKFISVPFEGVVAEIMRSVnhrhwgVVLKR--MMLKAAAEIARDYNASGLVMGdAVAQVSS-------QTLTNLNVVDR---ASDEVVLRPLIAMDKQEIIRIAKDIG-------------------------------------------------------
>UniRef50_C8WPE1(27-179:210) ExsB family protein n=1 Tax=Eggerthella lenta DSM 2243 RepID=C8WPE1_EGGLE  E=2e-05 s/c=0.34 id=41% cov=26%
-----VAFSGGCDSSFLLAAALRAGCDVRA----YGVRTafqpAFEIEDAQRLAAELGA-DFELVDADVLAQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B7J5X6(4-179:352) tRNA-specific 2-thiouridylase mnmA n=3 Tax=Acidithiobacillus RepID=MNMA_ACIF2  E=2e-05 s/c=0.29 id=34% cov=26%
-KKALIALSGGVDSAVAALLMQGQGYELTGVTMRLWPRSRccdeKDIEDAAEICARLGI-PYTVLD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q2NEC4(1-62:392) Argininosuccinate synthase n=4 Tax=Methanobacteriaceae RepID=ASSY_METST  E=2e-05 s/c=0.83 id=34% cov=27%
MEKVVLAFSGGLDTSVCVKLLQEKYNmEVITACVDVGQPED-EIKKPEAAAQKIGSDKHYTID-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B9B2T1(252-364:468) Putative uncharacterized protein n=2 Tax=Burkholderia RepID=B9B2T1_9BURK  E=3e-05 s/c=0.45 id=24% cov=40%
----------------------------------------------------------------------------------------------------------------SIGGSLIVTG-HEAKHRS---CYPGFTTKLSRFVEALTGKRVKFYHPALFETKGAVLRaLADAGENVRAVLGRHRSCscdarltSRDEQMFHCGVCGNCLLRR------------------------
>UniRef50_A7GTS8(180-344:403) Probable tRNA sulfurtransferase n=5 Tax=Firmicutes RepID=THII_BACCN   E=3e-05 s/c=0.31 id=23% cov=63%
--KVMVLLSGGIDSPVAAYLTMKRGVSVEAVHFHsppfTSERAKqKVIDLAQELTKYckrvtLHLVPFTEVQKTINKEIPSSYTMTVMRRMMMRITER---------------------IAEERNALAITTGESLGQVAS------QTLDSM-HTINEVTNYPV--LRPLITMDKLEIIKIANEIG-------------------------------------------------------
>UniRef50_Q2LWA6(21-89:372) tRNA-specific 2-thiouridylase mnmA 1 n=1 Tax=Syntrophus aciditrophicus SB RepID=MNMA1_SYNAS  E=3e-05 s/c=0.74 id=38% cov=26%
-KRVLLAISGGVDSSVAALLLKEEGYEVAGVTMCLGVREEenkvrccgREaIEDARGVCEILGI-PHYVLD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_UPI000194D842(5-66:397) PREDICTED: argininosuccinate synthetase 1 n=5 Tax=Amniota RepID=UPI000194D842  E=6e-05 s/c=0.81 id=35% cov=27%
-KGTVVLaYSGGLDTSCILVWLKEQGYDVVAYLANIGQKEDFE--AARRKALALGAKKVYIEDIS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C7X359(140-365:427) Putative uncharacterized protein n=1 Tax=Enterococcus faecalis Merz96 RepID=C7X359_ENTFA  E=7e-05 s/c=0.22 id=19% cov=89%
----VCMFSGGLDSFIGSIDILRGQTTSNTLFVsHYGGGSKGTKGYQDLLVKEM--INHFSSLSLSNFFSFYSA----AMKTPTGQDE----PTT----RSRSFMFFAHAIALTPDNAKLIIpenGFVSLNIPLYfsrngssstRTTHPFYMNLFQKILNI-LGINVRLENPYQFLTKGQMMNNCLDKEFLSRNIINTMSCSHPEQARwsgcsdpiHCGYCIPCTIRRASINEFCSPDPTLYRYL-------
>UniRef50_A8TGM5(16-80:250) ExsB family protein n=1 Tax=Methanococcus voltae A3 RepID=A8TGM5_METVO  E=8e-05 s/c=0.77 id=30% cov=29%
-KKVIVSYSGGVDS-TLVAKLAQNGEDCVAVTIDNGFFSKSSLKYAEKKAKLMNLK-HVIIDVNQLDE-------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B5YGH6(1-59:342) tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase n=1 Tax=Thermodesulfovibrio yellowstonii DSM 11347 RepID=B5YGH6_THEYD  E=9e-05 s/c=0.84 id=24% cov=25%
MEKVLLAMSGGIDSSVAAYLLREKGMAVEGVFFiLFDEPANIEL--AKQTANFLNIKLHI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C1XLL9(273-360:611) Asparagine synthase, glutamine-hydrolyzing n=1 Tax=Meiothermus ruber DSM 1279 RepID=C1XLL9_MEIRU  E=0.0001 s/c=0.56 id=48% cov=23%
-----VSLSGGLDSSLVAALAAQQHERV--VGFCYGhpQAPRSEGPLARELAQKAGIDVHFV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C7N321(3-195:353) tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase n=1 Tax=Slackia heliotrinireducens DSM 20476 RepID=C7N321_SLAHD  E=0.0002 s/c=0.25 id=39% cov=27%
-QRVLVGMSGGVDSSVTAYLLLRQGYEVVGATMNlYdpgrlgvpdvrdG--ESNDLEDARSVANRLGI-AHHVLDFGC----------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D0JAY8(193-252:588) Bifunctional argininosuccinate synthase/acetyltransferase activity of N-acetylglutamate synthase n=4 Tax=Bacteroidetes RepID=D0JAY8_BLASB  E=0.0002 s/c=0.80 id=30% cov=26%
--KIVLAYSGGLDTSYCLKYLIQEKYEVHTVIINTGGFNKDELEEIEDRAISIGSKSHKTIE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q3IME2(6-65:400) Argininosuccinate synthase n=20 Tax=Archaea RepID=ASSY_NATPD   E=0.0002 s/c=0.80 id=44% cov=26%
--RVALAFSGGLDTTVCVPLLEEEygYDEVIGVTVDVGQP-EAEFKEAEETAEALDLE-HHVVD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C7H5W9(180-344:399) Thiamine biosynthesis/tRNA modification protein ThiI n=9 Tax=Bacteria RepID=C7H5W9_9FIRM  E=0.0003 s/c=0.29 id=24% cov=68%
--RALNMLSGGIDSPVAAYRMAKRGLALDHIHFAsppYTSeRAKLKVKAlAQKITPYTGSSNLFVVPYTKPQEY--------------IRDNAPDVLFTVLMRRSMM--RIANRIATRQGCEALITGESLAQVAS------QTVKALQCTDA---AQDLPILRPLIGMDKTEIIETSRHIGTYEtsiLPYED-----------------------------------------------
>UniRef50_A6D100(47-288:372) Putative uncharacterized protein n=1 Tax=Vibrio shilonii AK1 RepID=A6D100_9VIBR  E=0.0003 s/c=0.20 id=22% cov=86%
--KAVSLLSGGLDSFIGAIDLLNS--DIDTLFVgHYAkdgtQHYQNQVEQA--------LKGHYP---DYFKGYVKGCLIFDKSVFKGGNQEidsENSQRS-----RSFMFLSMAAYLASSMGelCKLIVpengfialnvpldplrIGANSTKTV-----HPNFMSKMGEIFDF-LGLNIGLINPYRHMTKGEMMANCKNKSLLTKHAHETLSCASqskmrwdqgGFKANRLGGsggngncgyCYPCLIRKASFQKALITDNTEYVAI-------
>UniRef50_A4XFR8(2-215:225) 7-cyano-7-deazaguanine synthase n=2 Tax=cellular organisms RepID=QUEC_CALS8  E=8e-71 s/c=1.26 id=35% cov=92%
--RAVVVLSGGMDSTTLLYDVKNQGYETYTISFLYGQKHSKELEFAKKTCELLKV-PHKIVDISFFADLAPSALTKSSWSVPEGYYTDESMKQTVVPNRNMVFLSLATSYAISLKAQKLFYGAHAGDHPIYPDCRKEFVEAMKRSILLCDYQIVELEAPYVDLKKEDILKIGL---KLGVDYSLTWSCYKGGE-KACGRCGTCTERIEAFRKIGVKDP-------------
>UniRef50_B9MMB0(2-215:221) 7-cyano-7-deazaguanine synthase n=8 Tax=Bacteria RepID=QUEC_ANATD   E=2e-70 s/c=1.25 id=33% cov=92%
--RAVVVLSGGMDSTTLLYDVKSQGYEVFAISFLYGQKHSKELEFAKKTCSLLSI-PYKIVDISFFAELAPSALTTPDWNVPEGYYTDSTMKQTVVPNRNMVLLSISAAYAISLGAKKLFYGAHAGDHPIYPDCRKEFVEAMKNALYLADYIGLELEAPYVDMKKEDILRRGL---ELGVNYSLTWSCYKGGQ-KACGRCGTCTERIEAFKKVGVKDP-------------
>UniRef50_A3ZMY4(1-219:219) Predicted PP-loop superfamily ATPase n=1 Tax=Blastopirellula marina DSM 3645 RepID=A3ZMY4_9PLAN  E=1e-68 s/c=1.19 id=31% cov=95%
MSKVVAVVSGGMDSATLLYHLIDAGHDVRAISINYGQRHVKELDYARQLCDKVGVPQIVADLSAINPLFGANSLSGREIEIPEGHYAEENMKLTVVPNRNMILLSVSIAWAISQECVAVAYGAHSGDHAIYPDCRPEFAAAMDQAAKLCDWSAVELWRPFVDIDKGDI---AQRGSELGVPYELTWTCYKGL-AEHCGKCGACVERKEAFAKHGLVDPTAYMA--------
>UniRef50_B2I4Y4(1-223:230) 7-cyano-7-deazaguanine synthase n=16 Tax=Bacteria RepID=QUEC_XYLF2   E=4e-68 s/c=1.16 id=38% cov=94%
MKKAVILLSGGMDSAVVTAIAQSQGFMVHALSIRYGQRHTSELDAAVRIARALNVVAHKVVDVD-LRSIGGSALTDD-IEIPDA--GGEGIPVTYVPARNTIMLSLALGWAEVIGAADIFCGVNAVDYSGYPDCRPQFITAFETLANLATkvgveGTQLHVHAPLQFLSKAEIVHEGLLH---GVDFGLTVSCYRADvDGRACGRCDACKLRVAGFADAGVVDPTRYMEL-------
>UniRef50_Q8YM45(2-227:229) 7-cyano-7-deazaguanine synthase n=14 Tax=cellular organisms RepID=QUEC_ANASP  E=4e-67 s/c=1.13 id=37% cov=95%
--KAVILLSGGLDSSTILYQAKADGCECYSISFDYQQRHRRELHSAFLVAQTAGIVQHQVINFD-LRLWGGSALTDDNIDLPQERSldaMSQNIPVTYVPARNTIFLSFALAYAEAIAAQRVYIGVNALDYSGYPDCRPDYIEAMQEVFRLGTkqgreGQPINIVAPLINLKKTEIIQLG---NQLGVPWNLTWSCYAGGDV-ACGVCDSCRLRLAAFAELGLEDPLPYAYLK------
>UniRef50_B3QPB3(2-219:227) 7-cyano-7-deazaguanine synthase n=4 Tax=cellular organisms RepID=QUEC_CHLP8  E=5e-66 s/c=1.16 id=31% cov=92%
--KAVLLVSGGMDSLVATALAHHHGFELAAMHVNYGQRtWQKELECFRQICDHYGIEKRLEIDAGFLGAIGGSSLTDAAIPVGPADLAGTDIPTSYVPFRNANFLSMAVSWSEVIGANRIYIGAVEEDSSGYPDCRKVFYDAFNQVIEHGTrpETSIEIVTPLIDMSKAEIVKRG---MELDAPFHFSWSCYKS-EGKACGVCDSCARRLRAFASVGIADP-------------
>UniRef50_B0S9S9(16-247:248) 7-cyano-7-deazaguanine synthase n=13 Tax=Bacteria RepID=QUEC_LEPBA   E=3e-65 s/c=1.08 id=37% cov=93%
-KGAIVLLSGGLDSTTCLYLAAKDFgypknkkLPLLALSFDYSQKHKIELTKSKKIAKTLGIK-HVIQKLDP-GFFLGSSLTESKIKVRKnakslFSGDETEIPNTYVPGRNILFLSFALSLAEGHGYDSIYIGVNALDYSGYPDCRPEFIDSFQKMANLGTKKGvsgtgdsIQIKTPLLHLGKKEIIELG---MSVGAPLGLTHSCYDPVSGKPCGKCDSCILRAKGFLEVGLKDPA------------
>UniRef50_C1D6L0(10-221:229) 7-cyano-7-deazaguanine synthase n=6 Tax=Bacteria RepID=QUEC_LARHH   E=2e-64 s/c=1.17 id=43% cov=92%
---ALVVLSGGQDSTTCLYWALSRFAQVSAISFDYGQRHRVELDAARTIAAMAGV-GHTIIPINTFSALGGNALTDQQMSPDTGPDAETLLPNTFVPGRNLVFLTFAAAWAWPRGIRHIVTGVAQTDYSGYPDCRENTLRALELAINLGMESRMRLHMPLMFLSKADTVTLARTVGAMPA-LAFSHTCYAGA-VPPCGQCAACVLRAKGFAEAGIPDP-------------
>UniRef50_B2RJS2(5-218:220) 7-cyano-7-deazaguanine synthase n=5 Tax=Bacteria RepID=QUEC_PORG3   E=2e-63 s/c=1.14 id=28% cov=93%
-KDSLIVVSGGMDSVTLMYE--KRASIALALSFDYGSKHnARELSFARLHAERLGVE-HLIIPLDFIGQYFQSDLLLSGGDIPEGRYDEENMKSTVVPFRNGIMLAVAAGLAESRGLRRIYIANHFGDHAIYPDCRASFIRPMTEAVRCGTTNGVLIEAPYTDITKTDIARIG---ASLGIDYAETWSCYKGG-VFHCGVCGTCVERKEALHDAGIPDPTEY----------
>UniRef50_C1YMB1(18-233:243) PreQ(0) biosynthesis protein QueC n=1 Tax=Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 RepID=C1YMB1_NOCDA  E=3e-63 s/c=1.13 id=35% cov=93%
---VVVVFSGGMDSTTLLAHFAALRFRLVAVTVEYGQRHGKEVDAARAIARHYGAEHHILGIAGFGPLLRGSALTDARVEVPDGHYAEESMRDTVVPNRNAVLANLAASVAVARRAGTVALGMHSGDHFVYPDCRPAFVDALRHLVGVANEGfaAPRVEAPFMAWSKADI---ARHGVRLGAPLEHSWSCYKGG-DIHCGTCGTCYERREAFQEAGLPDPTEY----------
>UniRef50_C0CIL2(3-227:231) Putative uncharacterized protein n=1 Tax=Blautia hydrogenotrophica DSM 10507 RepID=C0CIL2_9FIRM  E=2e-61 s/c=1.05 id=33% cov=94%
-EKAMVLFSGGVDSTTCLGLAIEKYgvQNVIPLSVQYGQKHEKEVEAARRILEYYGIEGMELDLTPIFAYSDCSLLSHSEKEIPEASYaeqlrENEGVPvSTYVPFRNGLFLACAASIALSRECSCIYYGAHRDDAAGsaYPDCSESFFESMNRAVYEGSGQQIRIEAPFIKMNKAQIVAEGL---RLKVPYEFTWSCYEG-KEKPCGVCGTCIDRSEAFKVNGVEDPAY-----------
>UniRef50_B9L187(8-222:226) ExsB protein n=1 Tax=Thermomicrobium roseum DSM 5159 RepID=B9L187_THERP  E=1e-59 s/c=1.07 id=37% cov=91%
-QRAVVLLSGGLDSTTLAYLLDAYGFVLYGLSFRYGQRHERELEAARAIAEKLRFAEHRVVTID-LAQWGGSSLV-GSGEIP--RQPTSGIPSTYVPVRNLVFLAIAHAYAEAIDADAVAIAVSQVDYSGYPDCRGEFLAAYQQAADLAsrrfveTGRRIPVLAPFLDVPKSAIVRLGL---RLGVDYAETWSCYRGGE-RPCQECDSCRLRAQAFAEAGVPDP-------------
>UniRef50_UPI0001C418E0(3-207:211) queuosine biosynthesis protein QueC n=1 Tax=Methanobrevibacter ruminantium M1 RepID=UPI0001C418E0  E=2e-58 s/c=1.11 id=31% cov=89%
-KDVVLILSGGLDSTTLLYKLLNEGNNVTALSFNYGQKAAIEIERASEICK-MNDVNHFVFDIRNIVDLLSSSLTDKDND------NVQEPKSTVVPSRNTILLELATAFAISNNLEEVYYGAIKADTGDYPDTTPEFLKQINELNKVNNYEYIPVCAPFIDTDKKDVVKLAL---ELGVPIEKTWSCYVNNDGTPCGECFSCKSRIEAIKEAKEE---------------
>UniRef50_Q1CTN3(7-221:228) 7-cyano-7-deazaguanine synthase n=12 Tax=Helicobacter RepID=QUEC_HELPH  E=2e-58 s/c=1.06 id=41% cov=90%
----VVSFSGGQDSTTLAVWAKKRFKKVYLVGFDYAQKHSVELECAQKIASLLQL-PYEIISLDFLENITRSALFKNSNDLMGHsHVQNKDLPNSFVPNRNAIFITLLHSYAQKIGASNIALGVSQADFSGYPDCKEDFIKSIEHALNLGSNTAIKILTPLMFLNKAQEFQMAKDLGVLDLVIKETHTCYQGERkilhayGYGCNECPACQLRKKGYEEF------------------
>UniRef50_C7ML00(15-240:240) ExsB protein n=9 Tax=Bacteria RepID=C7ML00_CRYCD   E=3e-56 s/c=0.97 id=36% cov=93%
---ALVLSSGGVDSTTCLALAVDRFgqANVSTVSFFYGQRHSRELDAAAAVAEHYGVH-HYVLDLASVMHYSNNALMATSTQhVPHGSYaqqmEDDGHPNTYVPFRNGLMlsaAAALAASLFPDTSCALYLGAHADDAAGnaYPDCSPAFTAHMGRAISFGTYGNVRLETPFVNQNKAQVVAEGL---RLGVPYEMTWSCYEGGE-KPCGTCATCLDRIAAFEANGVKDPVSY----------
>UniRef50_D2RLP8(3-229:232) ExsB protein n=3 Tax=Bacteria RepID=D2RLP8_ACIFE   E=2e-55 s/c=0.96 id=32% cov=93%
-KKALVLSSGGVDSTTCVSVAVEEFgkENVSTVSIFYGQKHRKELECARKVAEYYGL-PHYELDLSKIFQYSNCSLLDHSTEeivhesyEQQIAENGEGKVSTYVPFRNGLMLSAVASLAmsiYEKDDVSIFIGAHADDAAGnaYADCSEAFIGAMGKAISLGTYNQCHIVAPFASCSKAGVVKRGL---ELHTPYDLTWSCYEGG-DKPCGTCGTCIDRARAFAANGVKDPA------------
>UniRef50_C0WAE7(3-229:233) Archaeosine biosynthesis protein queC n=3 Tax=Bacteria RepID=C0WAE7_9FIRM  E=8e-55 s/c=0.95 id=31% cov=93%
-KKALVLSSGGVDSTTCVSVAVHElGREnVATVSIFYGQKHRKELDAAQKVADFYHV-PHYELDLSKIFQYSNCSLLSHSTEeiihesyEDQIAQNGEGKVSTYVPFRNGLMLSAVASLAMSLfekDDVDIYLGAHADDAAGnaYADCSEAFTDAMGKAISIGTYEQCHLVAPFVEVNKAGIVKKGL---ELGTPYELTWSCYEGG-DRPCGTCGTCIDRARAFAANGVPDPA------------
>UniRef50_B4E7W5(10-235:244) 7-cyano-7-deazaguanine synthase n=73 Tax=Bacteria RepID=QUEC_BURCJ   E=2e-54 s/c=0.95 id=49% cov=90%
---ALVLFSGGQDSATCVAWALERYQTVETLGFDYGQRHRVELECREGVREALKHRfpawsdrlgDDHMIDLSVLGAISDTAMTRTI----EIETTANGLPNTFVPGRNLMFMTIAAAIAYRRGLRVLVGGMCETDFSGYPDCRDDTMKALQVALNLGMDTRMVLETPLMWLDKAQTWQLAEQLGgdaLVELIRVETHTCYVGERAElhdwgfGCGECPACKLRKRGYEAYLK----------------
>UniRef50_C8PJP9(2-388:391) Queuosine biosynthesis protein QueC n=1 Tax=Campylobacter gracilis RM3268 RepID=C8PJP9_9PROT  E=7e-45 s/c=0.47 id=34% cov=94%
--RALCVISGGMDSATCAYIARREGYEIVALHFDYDQRTmGKERECFGKICDDLGVAKRLILDARFIAQIGGSALTDGTLPIRkgaaelcgaanttgaeidsaansksaelgelnfietnsiaevngqnsiaanstnaetggqnftasnfmassadatlgadsardsrlqsgeiliqdaeillggdefspqgskilacddkissqgskilvqegeissqsgaqpqqgdkisskraegeipsqsqsdkispsSGESAFSDLPSTYVPFRNGVFLSIAAALAEKERCDAIFIGVVQEDSSGYPDCGASFIAAFERALELGTSRDFhpRIKTPLVHLSKAQIVSLALEI---GVPLELTWSCYE-REDAACGLCDSCLLRLKGFAGAGAKDKIPYA---------
>UniRef50_Q8ZVX7(8-246:269) 7-cyano-7-deazaguanine synthase n=7 Tax=Thermoprotei RepID=QUEC_PYRAE  E=2e-43 s/c=0.74 id=30% cov=92%
--RVVAVVSGGPDSTCYTALWLKRGCDVHALSFLYGQKAVVEVERAQLLLRRLDgiaaergwgrVVEHRVVDLSSLGELWRGTQLTD----PSVSVEQSYTPTVVVPIRNVVMAAVATAYAYTVGRNAgaktyVILGSHYDDIKPredtweplYPDCSPECVEAMQTAFRICHfrgERGVEIWTPSReGLRKSQLLKMC--HQEVGDLIYDTWSCYKSGEA-HCGSCESCKNRHAAFIEAGLPDCTAY----------
>UniRef50_A8URJ3(1-202:203) Putative uncharacterized protein n=1 Tax=Hydrogenivirga sp. 128-5-R1-1 RepID=A8URJ3_9AQUI  E=6e-39 s/c=0.81 id=25% cov=87%
MKKVGVLFSAGVESTSLLVYYLERGYLTLPLYARCGlSWERTELKWSERLWAFL---KYRYKNLMPLKTFPASGL-------------QPSKGSIEIPLRNITLVMGAVVHAYVKGIRKVALGSLG--IYPFPDNNRDYLDRLEALISEGARENISLETPFMGMEKWEVVREFYR----KAPYRLTFSCVKPIIGKHCGKCEKCLERKEGFLKAGVPDPTSYVS--------
>UniRef50_A9GG06(117-351:435) Putative uncharacterized protein n=1 Tax=Sorangium cellulosum 'So ce 56' RepID=A9GG06_SORC5  E=6e-25 s/c=0.49 id=20% cov=92%
---AVCLFSGGVDSLIGAINLLEsdRKSRVVLVG-HYDSTHTPGTQKvlADELIQEYGDER----VLPLRVLVRPAPIRDGVQAYPLPAVKESTTRS-----RSLVFLGLGMAVAAALGpAVPLYIpenGFIAINVPLHgsrvgscstRTTHPYFLDRIANALGV-VGVKNPIVNPYVYKTKGEMVRECKNQDLLRRVAHITVSCAHPERKQnetntwpNCGYCYPCLIRRAAFNWAGFESSSMYARYR------
>UniRef50_A8AM74(157-377:446) Putative uncharacterized protein n=8 Tax=Gammaproteobacteria RepID=A8AM74_CITK8  E=1e-24 s/c=0.52 id=21% cov=79%
----VSLFSGGLDSAIGVIDFLSSGRKPLLISHSY----KGDKTKQDQIA-------HKIREKGTFSRLRSSA-----NPIGRGMTRDITMRT-----RSLNFLAFAL-----VGAYAVKQINNHKDLSIFvpengfislnaplthrrvgslstRTTHPYFIGMIQELFN-NLGFGVRLINPYQFMTKGQMVSNCKDSKMLSEIVDLTVSCSHWKRKnQQCGYCVPCMIRRAALMKG------------------
>UniRef50_B1M991(150-364:435) Putative uncharacterized protein n=2 Tax=Proteobacteria RepID=B1M991_METRJ  E=3e-24 s/c=0.53 id=18% cov=89%
-----CLFSGGLDSYIGALDLIAQGERPLLVSHAYRGDRRYQDRTAHALpvaCARFSANAHPTWSGPsdvSMRTRSFNFLAYGAAAATAISQMRAGNRVTLWVPENG-LIALNAPLTPRR------IGSHST-----RTTHPYFLQSMQNILD-AVGLPVAIVNPLRHQTKGEMVLRHARDPAFVAQAVRTVSCGKWKRdGTQCGRCVPCLIRRASFHAADIADTTGYRS--------
>UniRef50_Q1LLD1(137-349:419) Putative uncharacterized protein n=1 Tax=Cupriavidus metallidurans CH34 RepID=Q1LLD1_RALME  E=6e-23 s/c=0.52 id=20% cov=85%
-RDCVALLSGGLDSLIGGIDAVAKMRRPIFVS----QLAYEDSERQRQYAAALGGAAWH------------------QQWSHRIDPAAPREPST--RARSMGFYAlavLATSLLTTTGPAEILVpenGFISVNPPLLPgrmaslstrTTHPLFMKQLQGLLK-AVGIPANLSMPYRFKTKGEMMMECLDQKLLAHFASDSTSCgrYRTYNRTHCGRCVPCMVRRAAFLRWGQADDTRYK---------
>UniRef50_A4T1U6(144-374:454) Putative uncharacterized protein n=2 Tax=Actinomycetales RepID=A4T1U6_MYCGI  E=2e-20 s/c=0.44 id=22% cov=84%
---AVSLFSGGLDSLTGVIDLLEEDPDrrLCLISHNEGdQASTAQKTLTAALREHYGQDRL---ELRSLFLRPAPAVAGQARPLPPERE-------TTTRARSLLFLTAGLALAASVGPDVpVYIpenGFIGINVPltrarsgsySTRTTHPQFMQLLRTAAD-AVGVCNPILNPFRLKTKGEILASSRNPELLRSLAPNSISCSHPEAARyavrkqgNCGYCFPCLIRR------------------------
>UniRef50_Q8R5Z5(1-202:343) tRNA-specific 2-thiouridylase mnmA 2 n=12 Tax=Fusobacterium RepID=MNMA2_FUSNN  E=5e-20 s/c=0.50 id=24% cov=81%
MKKVVIGMSGGVDSSVSAYLLKEQGYEVIGITLN--QHleeNSKDIEDTKKVCDKLGII-HEVVNIrkdfeNIVIKYFLEGYNSGKTPSPCIICDDE------------IKFKILFDIADKYNAEYVATG-HYTSVEYSEVFSKYLLKSVHsiikdqsyMLYRLSPDKLERLIFPLKDYSKQEIREIA-----LKIDLEVH------DKKDSQGVCFA----KEGYKEFLKEN--------------
>UniRef50_Q12C76(147-365:466) Putative uncharacterized protein n=1 Tax=Polaromonas sp. JS666 RepID=Q12C76_POLSJ  E=8e-19 s/c=0.44 id=21% cov=84%
--------SNGLDSFALANQVQRDSSTTELILIN--------VQAA-----------HRLTNWKNLGRARDKDMQAVQVAVFFNEPHRTEPSFRSRPFIYDMLAGYGASLAQP--AKVVIpengQGSLGgslvplGDEAPHRSCHPGFTSRLTRLVNALTNVTVRFEHPALFQTKGQVLaQLASQKSASEAWLAGHRSCsydarhsSQDKRSMHCGVCGNCLLRRVALKWTGIEDTTDYRA--------
>UniRef50_A0PSW2(135-349:420) Putative uncharacterized protein n=1 Tax=Mycobacterium ulcerans Agy99 RepID=A0PSW2_MYCUA  E=9e-19 s/c=0.45 id=25% cov=81%
--DAVSLLSGGLDSLSGAVLK--------------------------------GAPGLFLSHTDNPTVTGAqrrtwNWLTSNGVEGECVRLslnEASRKRENTTRTRALLFYALAVALADARGIDRVevsengFTGLNlslGNDRGGVLSTRsthPWTMHLMQRLLDDA-GIDIELVNPYEWQTKGELVRaAADVCPAFAEGLVTTLSCakldgrtYKGGNpNLNCGLCVACLTRRASIRAAGLEDKTPY----------
>UniRef50_A0B2R8(142-358:428) Putative uncharacterized protein n=4 Tax=Burkholderia cenocepacia RepID=A0B2R8_BURCH  E=1e-18 s/c=0.44 id=20% cov=87%
----VCLLSGGLDSLVGALDLTEEGRHPLLVS----QTAKGDKETQSRFAIGLGGNDRHLQwnqnIRPKVEDIEGSTRGRSIGFFAFAAVAADHLATTitalprpvevFVPENGLISLNI------PLNPGRV--GSLSTKT-----THPVFMARLQALWDE-LGIRAVLRLPYAAMTKGEMMAECRASTVLADVASEATSCGRFVRNgyKHCGRCVPCLVRRASFIRANLRDDTTY----------
>UniRef50_C5CE34(177-342:404) Thiamine biosynthesis/tRNA modification protein ThiI n=1 Tax=Kosmotoga olearia TBF 19.5.1 RepID=C5CE34_KOSOT  E=1e-18 s/c=0.57 id=25% cov=65%
---ALLLLSGGIDSPVAGWYALKRGITLHAIHFasppYTGEKAfEKVLDLAKALTKYNGGRDMLLYRVHF---------TKLQLAIHRNVRESLSL----VIQRRAMM-RIATKIAKEHGYKAIVTGENLGQVAS---------QTIENLHTIGSATDILVLRPLTGFDKIETIQIAKK---------------------------------------------------------
>UniRef50_Q5JCY1(182-340:381) Probable tRNA sulfurtransferase n=14 Tax=Thermococcaceae RepID=THII_PYRKO  E=5e-18 s/c=0.59 id=18% cov=69%
--KVVALLSGGIDSPVAAFLMMKRGVEVIPVHIYMG---EKTLEKVRKIWNQL-KKYHYGGKAELIVVKPQN----REEMLKKIKELGKEKYTCVLCK--FMMVKHADRIAKEFGAKGIVMGDSLGQVAS---------QTLENMYIVSQASDLPIYRPLIGLDKEEIVDIAKKIGTFEL---------------------------------------------------
>UniRef50_C6J374(180-344:410) Thiamine biosynthesis/tRNA modification protein ThiI n=2 Tax=Bacillales RepID=C6J374_9BACL  E=1e-17 s/c=0.56 id=27% cov=68%
--KAMLLLSGGIDSPVAGWSALRRGLEIECVHFHsYPFTSKkaeqKVIDLANVLAQYSGFIKLHLVPFT-------------EIQTKLAQTGQDNLIITM--MRRA-MLRIATKLAERNGALALVTGDSLGQVAS------QTLSSMN---AIGRVTNLPILRPLVMTDKVDIIAMAQQIGTYDlsiLPYED-----------------------------------------------
>UniRef50_Q5P5F5(141-360:457) Putative uncharacterized protein n=1 Tax=Aromatoleum aromaticum EbN1 RepID=Q5P5F5_AZOSE  E=1e-17 s/c=0.42 id=22% cov=87%
---AIIAYSDGMDSRAVAGLESSRLGR-------------------RLVRMRVGSKQHDVSKKERLR-IPFTALPYS-VKLENGRNAENSARS-----RGFKFSVVSTMAAYLIDAPSVIVPESGQGAlapvllpvgQGYEDYRnhPVFTALMARFFNALLGYKIQYRFPRLWMTKGETLREFVDVCGSEARWATTRSCWQqsrqvavSGERRQCGVCAACILRRLSVHAAGlneLPKTYVWESLKAAT---
>UniRef50_UPI0001BC5A6B(1-193:345) tRNA (5-methylaminomethyl-2-thiouridylate) -methyltransferase n=2 Tax=Fusobacterium RepID=UPI0001BC5A6B  E=2e-17 s/c=0.47 id=23% cov=69%
MKeKVILGMSGGVDSAVAAYLLQKEGYEVIAVHFsvHNTEATQKELQDCQKIADKFSltlysyslekefrekIISYYLSETGKGKTPSPCPLCDDSIKFHLLFQEAEKRKANYV----------ATGHYASISRNNICnTTLLEVKHHIHKDqCY--------MLYRLSPKKLNKILFPLASLEKAEVRELARDIG-------------------------------------------------------
>UniRef50_Q0AM89(149-356:439) Putative uncharacterized protein n=1 Tax=Maricaulis maris MCS10 RepID=Q0AM89_MARMM  E=3e-17 s/c=0.44 id=19% cov=86%
----VCLFSGGMDSLIGAIDRIADGHRPLLVS----RSTRGDGGYQTYLHGMLPEVPSLRINDDIRGELQGEPSTRTRSIVflalaacaasAISRLHNDSIVPLIIPE-NG-FISLNPPLTVRR------IGALSTRTV-----HPHFISSLQAIFDE-VGIPAAIENPYFFKTKGEALRECRDQPLVTKLISKTTSCGKWKRyWQQCGRCVPCLIRRSAFHAAGIADET------------
>UniRef50_O67015(1-107:110) Putative uncharacterized protein n=1 Tax=Aquifex aeolicus RepID=O67015_AQUAE  E=1e-16 s/c=0.83 id=30% cov=46%
--------------------------------------------------------------------------------------------------RNFILCTAGALYGVPKGINTCAIGSLGM--YPFEDNKKEFFEKLSETISMSLGKEFYIETPFMGMHKHEVIK---RYGKF-IPLELSLTCINPVNGEPCGKCIKCKEREEAL---------------------
>UniRef50_C6D5K7(179-344:406) Thiamine biosynthesis/tRNA modification protein ThiI n=2 Tax=Paenibacillus RepID=C6D5K7_PAESJ  E=1e-16 s/c=0.53 id=25% cov=69%
--KAMLLLSGGIDSPVAGWMAMRKGLELEAVHFHsYPFTSdkakEKVIDLARRLSYYAGA-PLKLHLVPF-----------TDIQTRLVQAKQDSMMITL--MRRA-MLRITEQLADRNGAGGIVTGESLGQVAS------QTLSSMNV---IGRATVLPLLKPLIMMDKQEIINEAVRIGTFEtsiLPYED-----------------------------------------------
>UniRef50_C8WW19(179-336:400) Thiamine biosynthesis/tRNA modification protein ThiI n=2 Tax=Alicyclobacillus acidocaldarius RepID=C8WW19_ALIAD  E=2e-16 s/c=0.56 id=26% cov=65%
--KGLVLLSGGIDSPVAAWKAMKRGLALELVHFHsfpfTSERAQQKVEDLAAILTKWGGpmKLHLVSVTAIQAEIQRSA--------------PEGLR-TILLRR--MMVRAASRIADEVGAGALVTGDSLGQVAS------QTLSALN-AVDRATDH--TILRPLIAEDKLEIIELAKRMG-------------------------------------------------------
>UniRef50_B9JNY0(142-350:457) Putative uncharacterized protein n=1 Tax=Agrobacterium radiobacter K84 RepID=B9JNY0_AGRRK  E=4e-16 s/c=0.42 id=23% cov=83%
--KVVTPFSDGLDSRAVTAMMTAGGR------------------SDRLIRVRVGAK----TDDRPRTEHRKAPFLT--IPFKVKSGDRPFAEST-VRSRGFKFTLLSGIAAYLLGTHDIVMpesgqgalGPSLVQTShGYEDYRnhPLFFGRMERLVAAIFNYQVSYRLPRLWKTKGQTLGEFAALPVNPNEWVKTRSCWQqnrnssvDGKRRQCGICAACMLRRLSFHAAGLEEP-------------
>UniRef50_Q8TWX3(167-329:374) ATP pyrophosphatase involved in thiamine biosynthesis n=1 Tax=Methanopyrus kandleri RepID=Q8TWX3_METKA  E=4e-16 s/c=0.54 id=24% cov=71%
--RVVCLVSGGIDSPVAAWYAARRGCEVIWLHLDRG-KYGSEVDAVERLAGKFS--EWLPSDVELLIEDF-----EDFMESLEGLEGESARYRCVLCKRE--MIRRACDVCENVGAVAVVMGDVIGQVASqIPDN----LAVIDRVAR------FPVFRPLLGFDKNEVQRLSERLGLFEVSKEH-----------------------------------------------
>UniRef50_D1N6V4(192-349:400) Thiamine biosynthesis/tRNA modification protein ThiI n=1 Tax=Victivallis vadensis ATCC BAA-548 RepID=D1N6V4_9BACT  E=5e-16 s/c=0.55 id=24% cov=68%
--KVLTLLSGGIDSPVAAWQIMKRGCPTDFITFHSAPYTPPEtVDKVRGIAEHLNtFQQHGVLHLCNLA------------PMQKLIRDNCNERFRTVLYRRA-MLRIAEQVAKNTGCRALVTGEAVGQVAS------QTIVNMNT---INRAVDMLVLRPLVGADKLESIRIAGEIGTLEL---------------------------------------------------
>UniRef50_A2PQ54(152-369:444) Putative uncharacterized protein n=1 Tax=Vibrio cholerae MZO-3 RepID=A2PQ54_VIBCH  E=9e-16 s/c=0.39 id=16% cov=81%
----VSLFSGGLDSAVGAIDMINGSnvDKPLLISHSY----KGDGKKQKDI-KSLLRGKFSEFSFDISPKIIKSRRGKTDVSMR---------------GRSFNFIALAVlgvnALRSANNDDSISRIVIPENgyislnppltrrrigSHSTRTTHPFYISRLELLLNK-VGFNISLENPYQMKTKGEMVSECVDKVAIKKAVVLSVSCSNWHRKHiQCGRCVPCLIRRAAV---------------------
>UniRef50_A7I9U0(1-161:213) Thiamine biosynthesis protein n=2 Tax=Genera incertae sedis RepID=A7I9U0_METB6  E=1e-15 s/c=0.53 id=18% cov=68%
MAKLVSLISGGIDSPVAAYLMLHQGVEIIAVHMDNrPFTDEKNLHKAMNLIRHLQHLTQRPIKTYVVPHGPNH-----------IAFARNCERHLHCLFCRRMMYRIAERIAEKEGAVGILTGESLGQVAS---------QTLQNLMVENLVIRIPVVRPLIGMDKVEIIDIARRIG-------------------------------------------------------
>UniRef50_Q3SW10(144-347:452) Putative uncharacterized protein n=1 Tax=Nitrobacter winogradskyi Nb-255 RepID=Q3SW10_NITWN  E=1e-15 s/c=0.42 id=26% cov=74%
---AVIAYSDGMDSrAVAGLMAESLGERLVRV----------------RVGPKAGGRPFKGQREPFAAVPYSVAATGE----------------TSGRSRGFKFALISGIAAYLAEADVILVPESGQGAFGpalvtvahaYPDYRnhPLFTSRMERFLNALFRRPVRFVFPRLWHTKAETLRE--YAALPGSKWDDTKSCWRNARWSAlngnlvqCGICAACMLRR------------------------
>UniRef50_B7H703(180-344:404) Probable tRNA sulfurtransferase n=75 Tax=Bacteria RepID=THII_BACC4   E=1e-15 s/c=0.52 id=23% cov=63%
--KVMVLLSGGIDSPVAAYLTMKRGVSVEAVHFHSPpftsERAKqKVIDLAQELTKYckrvtLHLVPFTEVQKTINKEIPSSYSMTVMRRMMMRITER---------------------IAEERNALAITTGESLGQVAS---------QTLDSMHTINEVTNYPVIRPLITMDKLEIIKIAEEIG-------------------------------------------------------
>UniRef50_Q47DY3(149-377:457) Putative uncharacterized protein n=5 Tax=Proteobacteria RepID=Q47DY3_DECAR  E=3e-15 s/c=0.37 id=20% cov=84%
--DAVSLFSGGLDSLIGAIDLLEAGRTPLLVS------HAGEGATSDAQnVLFAALKKHF---SAVAFDRLRVWMLFPADLVQGVSSENSTR------GRSFLFFALGVFAGTGLGTDFVLrvpeNGLIALNVPLDPlrlgsnstrTTHPYYIARWNDLLGHLGISG-RVENPYWAKTKGEMASACANPVLLKALAPYALSCAHAANARHlgikgrgieqCGYCLPCLIRRAAL---------------------
>UniRef50_B6YWN1(2-162:196) ThiI-related protein n=5 Tax=Euryarchaeota RepID=B6YWN1_THEON   E=3e-15 s/c=0.52 id=21% cov=69%
--KAVALLSSGIDSPVAIYLMLRKGMEITPVHFK--QSDKKESKVLElcEILSKYGKLNEPVIVDAY------------EEQAPVFSKLVEIGKAKWTClFCKYTMLRKACRVGHEIGAKAIVTGDSLGQVAS---------QTLDNLLIISQASDLPILRPLIGRDKEEIVKIAKEIGTFEISIE------------------------------------------------
>UniRef50_C5NYW3(180-337:416) Thiamine biosynthesis/tRNA modification protein ThiI n=3 Tax=Bacillales RepID=C5NYW3_9BACL  E=4e-15 s/c=0.53 id=22% cov=66%
--KALLLLSGGIDSPVAAHTLQVKGVEVEMIHFQSPPFTSAEaLQKIFDLTIKLsqvvGRIKLHVVNFTKLQ-------TEIVKRVPSNYTMTSTRRF---------MLRIAEEVAKKEGCLAIATGESLGQVAS------QTLESMNC---INEVTNLPVLRPLLTMDKVDIIKIAQEIDTLE----------------------------------------------------
>UniRef50_B5YCZ9(4-194:345) tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase n=2 Tax=Dictyoglomus RepID=B5YCZ9_DICT6  E=4e-15 s/c=0.44 id=23% cov=69%
--KVAVGMSGGVDSSTTAYLLKKEGYEVIGLTMNIA--YSDSIKDAEKIAKYLNIPHFYVD-------------LRKEFEEQIIKYFIDSYKSGYTPNpctfcNRIIKFGLLLKKAQELGAEYLATGhyvrkVWDEEKKVFLLKRAKDLKK-DQSYFLAYLTQEQIEkslFPLGDLTKNEVRKLAEEIG-------------------------------------------------------
>UniRef50_B1L665(176-338:373) Thiamine biosynthesis/tRNA modification protein ThiI n=1 Tax=Candidatus Korarchaeum cryptofilum OPF8 RepID=B1L665_KORCO  E=6e-15 s/c=0.51 id=17% cov=70%
--KVLALISGGIDSPVAAWLLMRRGAQIIPLHFR---KSSAEEETFIKIVNVLRRYSYGVKMEPMILEHG---------EFLSEISREAREWTCLLCKRRMLL--TANRIAKEIGAHGIVTGDSLGQVAS------------QTLANLEVESRClekPVFRPLIGMDKEDIVKIAKEIGTYDISISYKESC-------------------------------------------
>UniRef50_D0WEQ1(184-341:421) Thiamine biosynthesis/tRNA modification protein ThiI n=1 Tax=Slackia exigua ATCC 700122 RepID=D0WEQ1_9ACTN  E=7e-15 s/c=0.53 id=24% cov=68%
--KVVCLLSSGIDSPVALWRMARRGATCVAVHFSgRPQTQATSEFIVDDIA-------HTIEGFGGIARMYVVPFGDYQRTIAGTVPQRLRI---IVYRR--LMMRVAAAIARREGAKALVTGESLGQVAS---------QTLDNLAATGSAVDMQVFRPLIGSDKLEIIADAQKLGTFDL---------------------------------------------------
>UniRef50_C7RPK0(150-387:458) Putative uncharacterized protein n=1 Tax=Candidatus Accumulibacter phosphatis clade IIA str. UW-1 RepID=C7RPK0_9PROT  E=1e-14 s/c=0.35 id=23% cov=87%
--DSLCLFSGGLDSLIGAINLLQAESAPLLIS-HFGESATSDAQ------NKLFAKLKKQYARSAFDRLRVG-MTFDDGLVKDVGSENSTRGRSFLFFalgvfagtglRNGFTLKVPENglIALNVPLDPLRLGSNST-----RTTHPYFMARWNDLLDE-LGIDGRVENPYLPMTKGEMVLACANQKLLLELAPMSLSCahpanarwqgHKGRGIEHCGYCLPCLIRRAALNRAWGE---------------
>UniRef50_A2DK37(204-360:436) Thiamine biosynthesis protein ThiI, putative n=2 Tax=Trichomonas vaginalis RepID=A2DK37_TRIVA  E=2e-14 s/c=0.52 id=20% cov=65%
--KTVVLLSGGFDSPVAAWSVMRRGCQVVYVHFHsspYGE-WRSSVGKVRKIVQQL-------ATWGGPDTFYSVSIGEQQRQIA---LKGPSKLRVTLYRR--LMVRIAAAIAKRNKCTALTTGDNLGQVAS------QTIESMTTI--QAAINPLLILRPLLADSKEEIIEKA-----------------------------------------------------------
>UniRef50_B4R9S2(150-384:456) Putative uncharacterized protein n=1 Tax=Phenylobacterium zucineum HLK1 RepID=B4R9S2_PHEZH  E=2e-14 s/c=0.35 id=21% cov=88%
--DSVCLFSGGLDSFIGAIDLLADGKAPMLVSHYWdGITSTHQTYCADVIAKRFPKQRFHHLRARVG---FPNDLVDGSAGENTLR------------GRSFLFFALAAMAADALGVGLIHVpenGLISLNVPLDPtrlgalstrTTHPFYMARFDEILD-GLGLPIRLENRYRFQTKGVMAKNCADAALLNKEARHTMSCSSPAKARwakdedarqpkHCGHCVPCLIRRAAMVEGLGADHTPY----------
>UniRef50_A6LQW7(19-166:274) ExsB family protein n=4 Tax=Clostridium RepID=A6LQW7_CLOB8   E=3e-14 s/c=0.55 id=31% cov=61%
--KVVLAFSGGVDSTFLLRVAKEAlGDNVKAVTILSPYIPKWEIAEARELVRELGV-QHEIIEAPIIDSIKFNP------------EDRCYLCKTAV-------FTMILNVAKEQGYNCVIDGTNFDDIS---DYRPG-LKALKEL---------EVRSPLLEckLTKAEIRAFSKELG-------------------------------------------------------
>UniRef50_C4FTQ9(180-337:404) Putative uncharacterized protein n=1 Tax=Catonella morbi ATCC 51271 RepID=C4FTQ9_9FIRM  E=3e-14 s/c=0.51 id=21% cov=65%
--RALLMLSGGIDSPVAGYQMMKRGLEIEAVHFASPPYTSPQaIEKTKKLTAQL--------------AQYGRSLTYHCVPFTEIQEEIKDKVhddfSMTIMRR--MMLRVMEALLDRQQADAIVTGESLGQVAS---------QTLKSMRAINQVTSVPILRPLIAVDKNDIIVQAEAIG-------------------------------------------------------
>UniRef50_A2BKB5(181-340:388) Probable thiamine biosynthesis protein, ThiI n=1 Tax=Hyperthermus butylicus DSM 5456 RepID=A2BKB5_HYPBU  E=4e-14 s/c=0.50 id=23% cov=65%
--RALVLFSGGLDSPVAAWYTAKRGVEVDLLHFILAVPASA--RDAERVGRRL--------AELWLYGYKPKLFLVDFRPVTVTIASNTRRGYEQIVLRLAMYYA-AQLIAEKHGYDAVVTGESIGQVSS------QTLKNM-KAMAQALPLRLPLIRPLAGMDKEEIV--------------------------------------------------------------
>UniRef50_Q0C5H6(144-366:456) Putative uncharacterized protein n=1 Tax=Hyphomonas neptunium ATCC 15444 RepID=Q0C5H6_HYPNA  E=6e-14 s/c=0.36 id=33% cov=55%
------------------------------------------------------------------------SLPGAGVRLPEQSYRS----------RGFLFGAVAATAAgIMKGAEIVVpesgqgtFGpALTVIGHEHPDVRmsPIFTSALGRFVSRIFESPIRFVHPRVWSTKGETLA-ALQIAQLSEGWEVTVSCSRSSRrkiqgsvAKHCGVCANCLLRRQSL---------------------
>UniRef50_D0LKN2(189-347:401) Thiamine biosynthesis/tRNA modification protein ThiI n=1 Tax=Haliangium ochraceum DSM 14365 RepID=D0LKN2_HALO1  E=8e-14 s/c=0.50 id=22% cov=66%
-----LLLSGGIDSPVAGWSAMRRGCRVVAVYFHsfpyTGDKTKKKvLTLAQRLAAWQGSVPVHVVHFTEVQK--------------ALREHAGGRADLGVLMYRRMMLRAASRLALRDELSALVTGDSIGQVAS---------QTVENLGVVEDAASVPVLRPLLTFDKAEIVERAQQIGTYEV---------------------------------------------------
>UniRef50_D0Y5H1(169-381:638) Putative uncharacterized protein n=1 Tax=Dehalococcoides sp. GT RepID=D0Y5H1_9CHLR  E=1e-13 s/c=0.37 id=21% cov=80%
----VMLFSGGLDSLAGAVELLEDSKDVICLVSHQSQPgtVKTQNGLFKALKDAYSDRVRHYQ--------FKCSLVST-----VNRAVEETQRT-----RAFLYTSIAYAIASSQRNPRFYVhenGVTSLNFARRQDginartsrtTHPRTLSLLQDFFSLVHGSKVQVATPFLFKTKSDIFRELSAHKRENLIPS-AVSCSKTFlnrkQASHCGGCFQCIDRR------------------------
>UniRef50_B5ZBR5(176-345:392) Probable tRNA sulfurtransferase n=15 Tax=Ureaplasma RepID=THII_UREU1  E=1e-13 s/c=0.47 id=24% cov=67%
--KALVLLSGGIDSPVASRLIMKRGISVDFITFITPPHtSQKALDKTIALAKQITLNNHLTK-----ANLYVCNFTKLQEEIAHISKESYRI---TLMRR--YFMRIAKRLAIDIKAGALVTGEALGQVAS------QTLNSMQTISSVL--NDFLVLRPLITYDKQEIISLAK----------------------------------------------------------
>UniRef50_C5RQ91(175-337:386) Thiamine biosynthesis/tRNA modification protein ThiI n=1 Tax=Clostridium cellulovorans 743B RepID=C5RQ91_CLOCL  E=2e-13 s/c=0.48 id=22% cov=68%
----MLMLSGGIDSPVAGYLMARRGTEVSSVYFHshpYTSERAKEkvIDLAKILASYTGQMKLYIV-----------PFTEIQMKIMELCPEDEL---TIIMRR--FMMRVSCTLAERNKIQSVSTGESIGQVAS---------QTMEGLIVSTDVADRPVFRPLIAMDKEDIMDISRKVGTYDtsiLPYED-----------------------------------------------
>UniRef50_Q8PWQ6(17-165:275) Conserved protein n=3 Tax=Methanosarcina RepID=Q8PWQ6_METMA   E=2e-13 s/c=0.52 id=26% cov=61%
---AVIAFSGGVDSTTLAALAFEElGDRALAVTIDSPLFPRHQLETASQAACEIGI-QHKILPFSLNSVPYFTANTINRCYFCKKA-----------------LLETLLEFAEKTGYNAVLEGTNASEIKG--ENRPGY-RAIQEA-------GEKIYSPFVEFnvTKEEIREIA-----------------------------------------------------------
>UniRef50_A4EC56(178-335:414) Putative uncharacterized protein n=1 Tax=Collinsella aerofaciens ATCC 25986 RepID=A4EC56_9ACTN  E=3e-13 s/c=0.49 id=16% cov=68%
--KVVTLLSSGIDSPVATWMLARRGAVCVPVHFSGRPQTPDTSEY---------LVQDIIRALEPGVQIGRLYVVPFGDCQREISVTCPSNLRVIMYRR--IMYSVAERIAHIEGAKAIVTGESLGQVAS---------QTLENIMAVNEAVKIPVFRPLIGSDKQEIIARAEEIGTFD----------------------------------------------------
>UniRef50_Q9YEW8(181-337:396) Probable tRNA sulfurtransferase n=1 Tax=Aeropyrum pernix RepID=THII_AERPE  E=4e-13 s/c=0.49 id=23% cov=66%
---SLALYSGGFDSGVAAWMIMRRGSPVHLAFYDFGVPEALEvaVEGAKTLA---GEWAWGYRPRLYVVNFRGAALIVNGLVKPSYR--------TLVLRR--LMLLHAQDLAAREGFEALVTGESVGQVAS---------QTVRNLRLISSGLELPVLRPLAGMDKDEIVEKSREIG-------------------------------------------------------
>UniRef50_C4DG87(146-358:420) Predicted PP-loop superfamily ATPase n=1 Tax=Stackebrandtia nassauensis DSM 44728 RepID=C4DG87_9ACTO  E=4e-13 s/c=0.36 id=23% cov=84%
---AVALFSGGLDSFCHAGLLRPA-SKVVLVSHGLGPNLR---ERKRELRAALGGE--TVMSAEFQVRINAVPGTERE-PHPRTRALLLLAAGVLVCAANGV----DTLHCPENGLLALHPAkapLWSQSATPIP---PMTVHLANALLD-SLDVDTRVVNPYAELTKGEVCERAVDAGWRRSLLGRTITCVNPDKKSsgrfgNCGYCRHCLVRHAAL---------------------
>UniRef50_A8S2P7(36-190:288) Putative uncharacterized protein n=9 Tax=Firmicutes RepID=A8S2P7_9CLOT  E=5e-13 s/c=0.50 id=35% cov=58%
-------FSGGVDSSLLLKTAADAaahtGRKVYAVTFDSRLHPSCDLEIARRVAGELGGI-HEVITVD--------------------ELEQESIKNNPV-NRCYLckrhLFSRLAELAEARGIRYILDGTNEDDMHVY---RPG-IRALKEL---------GIISPLaeLHITKAQVKALASEYG-------------------------------------------------------
>UniRef50_A1RWZ9(176-333:484) Thiamine biosynthesis/tRNA modification protein ThiI n=1 Tax=Thermofilum pendens Hrk 5 RepID=A1RWZ9_THEPD  E=7e-13 s/c=0.48 id=25% cov=65%
--KVLALISGGYDSAVAAWYMLKRGAEVHYLYCNMaGDLTKSlVLSVAKKLADswSYGYKPrLYVADF--------SPLLRELRAKVAPELFG------VVLKR--YMYRVAEAIAGRIGAIGIVTGESLGQVSS---------QTLENLYVASQATSMPIYRPLIGFDKEEIISKSKEIG-------------------------------------------------------
>UniRef50_D2B6F2(190-347:400) Thiamine biosynthesis protein ThiI n=2 Tax=Streptosporangineae RepID=D2B6F2_STRRD  E=7e-13 s/c=0.48 id=21% cov=68%
--RGLVLMSGGIDSPVAAYRMMRRGLRVDFLHF-----SGIPFTTSESIYKAYAL----VRALDRFQGRSRLWVVPFGKAQQSIKASGQDRLAVISQRR--LMLKTAEEVARRLRAGALITGDSLGQVSS---------QTLQNITAQDDAVDLPILRPLIGLDKTEIMAEARRIGTLE----------------------------------------------------
>UniRef50_Q58341(190-355:381) Probable tRNA sulfurtransferase n=11 Tax=Methanococcales RepID=THII_METJA  E=1e-12 s/c=0.46 id=15% cov=67%
--KVLCLISDGIDSPVAAFMMIRRGCRAVLLHLK---MSEEALNKVRKIVEVLSDYD------TELEFVVYDYKKDIEDIVEKLKSIKKENYTCIFCKRK--MLKVAEKYAKYLDCDAIVTGDNLGQVAS---------QTLKNLRVISENINYPILRPLIGLDKNDIVKIAKEIG-------------------------------------------------------
>UniRef50_A5INK8(15-160:268) ExsB family protein n=6 Tax=Thermotogaceae RepID=A5INK8_THEP1   E=1e-12 s/c=0.52 id=33% cov=29%
-KKVVVMFSGGVDSTLLAKLTHEAlGENSVALTIDSPVIPRKEIEKAKRLAGLIGIR-HEFIELNELK--------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_UPI0000382ADB(14-158:178) COG0603: Predicted PP-loop superfamily ATPase n=1 Tax=Magnetospirillum magnetotacticum MS-1 RepID=UPI0000382ADB  E=2e-12 s/c=0.52 id=23% cov=44%
----------------------------------------------------------------------------------------------WWPYRNQMLVTLAGMRFVAEGLTEILLGAIRTDV--HADGRAPFLRTVDRLMHL-QEGGVRVMAPARHLSALELVRRSGIPRSL---LGATFSCH--VMEYACGRCRGC----------------------------
>UniRef50_Q47R41(203-358:422) Thiamine biosynthesis protein n=3 Tax=Actinomycetales RepID=Q47R41_THEFY  E=5e-12 s/c=0.47 id=23% cov=68%
--RGLVLLSGGIDSPVAAYRMMRRGLRLDFLHFSGMPFTGPE-----SIYKAYSLVR-QLDRFQNGSRLYVVPFGKAQQQLRNSGAERLQI----VAQRR-LMLKTAEALADRLNASALVTGDALGQVSS---------QTLANITALDDAVDLPILRPLIGMDKTEIMDQARAIGTL-----------------------------------------------------
>UniRef50_UPI00017F5D79(159-385:487) hypothetical protein CdifA_02378 n=1 Tax=Clostridium difficile ATCC 43255 RepID=UPI00017F5D79  E=5e-12 s/c=0.32 id=21% cov=88%
----VSLFSGGLDSFCGALRLLENNKKVFFVTC-------MEHKLLKKRVNDIYRRVDRGYPKLNKNIYVFSA--NPKRPMNVSKELLNKFSEDTSRSRSFLFMAVAIAVVSIINPkEGVYIPENGFIGINLPltksrlgSCSTRTthvwaLKRLNEILTL-LDINIPITNFYKYNTKGEIVDEFKNNKIFKECVKLTLSCSHPTHGRmagatppiNCGYCYPCMIRRASLYKIGFDD--------------
>UniRef50_C9RQ01(5-196:366) tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase n=1 Tax=Fibrobacter succinogenes subsp. succinogenes S85 RepID=C9RQ01_FIBSS  E=9e-12 s/c=0.38 id=28% cov=70%
-KRVAVGLSGGVDSALSAYLLKKQGYEVVGMTMAtwddsvkmpavegregcYGPSEDKNIEEAKLVAERLGI-PHYVVPVAE----------DYKREVLDYFRAEYRAGRTPNPcvrcNQSIKFGALQHA-ARKLGIDFDYFATghyARLDFKN-PDV-PFLYEALDEhkdqtyfLSRLSAEQLSTVIFPLGGMQKADVKALAKEIG-------------------------------------------------------
>UniRef50_C9RAV2(1-172:344) tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase n=1 Tax=Ammonifex degensii KC4 RepID=C9RAV2_AMMDK  E=9e-12 s/c=0.42 id=40% cov=26%
MTRVAVALSGGVDSATAAFLLLQAGYEVFGVTMLV---TGEEGEKAAEVAAKLKI-PHFVFDL------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C9YE01(5-84:143) Putative uncharacterized protein n=1 Tax=Curvibacter putative symbiont of Hydra magnipapillata RepID=C9YE01_9BURK  E=1e-11 s/c=0.91 id=51% cov=30%
---ALVLFSGGQDSTTCLAHALARYERVETIAFDYRQRHNVELEARlnvlREIktrfpqwAAKLG--EDHLLDLAVLGEVSETSL-------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q5LIS5(6-223:364) tRNA-specific 2-thiouridylase mnmA 1 n=5 Tax=Bacteroides RepID=MNMA1_BACFN  E=2e-11 s/c=0.33 id=29% cov=66%
-KRVLLGMSGGTDSSVAAMLLLEAGYEVTGVTFrFYEFNGSTEyLEDARALAARLGI-GHITYDARKVFQ----------EQIIDYFIDEYMSGHTPVPctlCNNQLKWPLLAKIADEMGIFYLATGhyvrkqWIDGNYYIAP---AEDVDKDQSFFLWGLRQEIlqRMLLPMGGMTKSE----------------------------------------------------------------
>UniRef50_Q9ZJQ0(2-177:342) tRNA-specific 2-thiouridylase mnmA n=22 Tax=Campylobacterales RepID=MNMA_HELPJ  E=3e-11 s/c=0.40 id=27% cov=26%
--KIAVLLSGGVDSSYSAYSLKEQGHELVGIYLKLHaseKKHDLYIKNAQKACEFLGI-PLEVLD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B0KAQ1(30-186:286) ExsB family protein n=21 Tax=Bacteria RepID=B0KAQ1_THEP3   E=4e-11 s/c=0.45 id=32% cov=29%
---ALIAFSGGVDSTFLAKVSYDvLGNRVLAVTATSPMHPKSELKEAVELAKKIGI-PHLVVEFNDILEI------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A1STI9(8-185:367) tRNA-specific 2-thiouridylase mnmA n=4 Tax=Proteobacteria RepID=MNMA_PSYIN  E=4e-11 s/c=0.40 id=27% cov=26%
--KVIVGMSGGVDSSVSAYLLQQQGYLVEGLFMknweedDTDQycAAAQDLEDAQSVCDKLGIPLHTI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C6BXJ5(21-161:269) ExsB family protein n=1 Tax=Desulfovibrio salexigens DSM 2638 RepID=C6BXJ5_DESAD  E=4e-11 s/c=0.50 id=27% cov=58%
---AVIAFSGGVDSTLLLHTAKEAlGDKAIAASISTPYVPQWEQGEAKEFAEQMEVK-HVVVDMGFPEELRMNP--------PEHCYTCKN-----------ILFSKLLEIAQENDIEHVLEGTNIDDLS---DYRPG-IKALREL---------EIRSPFVeaELTKQEI---------------------------------------------------------------
>UniRef50_C8WPE1(24-179:210) ExsB family protein n=1 Tax=Eggerthella lenta DSM 2243 RepID=C8WPE1_EGGLE  E=6e-11 s/c=0.45 id=31% cov=49%
-----VAFSGGCDSSFLLAAALRAGCDVRAYGVRTAFQPAFEIEDAQRLAAELGA-DFELVDADVLAQ----------GEICANGPDRCYRCKTF------IFSTILARMAE-DGFEVLADGTNVTDD---PANRPGF---------------------------------------------------------------------------------------------
>UniRef50_C3MZC6(172-326:373) Probable tRNA sulfurtransferase n=7 Tax=Sulfolobus islandicus RepID=THII_SULIA  E=6e-11 s/c=0.45 id=21% cov=65%
--KTVVLFSGGIDSPVATWMMMKRGSIPVILNFNLgGSVHRKfVLEELSVLRKWSGGHKLKLFIVNG---------TDVLIKLSQIE------KRNRVVMLKRVMYKVAERLCDKANVKSITTGESLSQVSS---------QTMTNLYVTEYGIKYPIFRPLIGFDKEEIVELARKIG-------------------------------------------------------
>UniRef50_Q1N4K9(180-335:483) Thiamine biosynthesis protein ThiI n=1 Tax=Bermanella marisrubri RepID=Q1N4K9_9GAMM  E=6e-11 s/c=0.45 id=16% cov=47%
---VLSLVSGGFDSNVASYLMMRRGMQTHYLFFNLGGSAH---EIGVKQVAHYLWENYSVSHGVKFITIPFEGVVSEILERIDNSYMG------VVLKR--MMLRAGSQIAESMGIDALVTG-------------------------------------------------------------------------------------------------------------
>UniRef50_B1VAX7(1-196:375) tRNA-specific 2-thiouridylase mnmA n=4 Tax=Bacteria RepID=MNMA_PHYAS  E=8e-11 s/c=0.36 id=23% cov=71%
MKKVVVGLSGGVDSAVSALLLKKAGYEVEAVFmrnwdsqlnFDFQGNPTlndvcpQELDYkdALKVSLQLGIKLHRVNFIEEYWQkvflYFINAFKNNLTPNPDILCNNEIKFKA--------FINYATSklkpqyIAMGHYARLIYDKNQKVSLACPLDKNKDqtyFLSQLK------TSQLKNILFPLADLTKKEVRKIALENG-------------------------------------------------------
>UniRef50_Q8EVH8(172-336:383) Probable tRNA sulfurtransferase n=1 Tax=Mycoplasma penetrans RepID=THII_MYCPE  E=1e-10 s/c=0.42 id=17% cov=68%
--RCLSLLSGGIDSPVASFLLQKRGQQVDYLTFITDDVTEITLNKLKSLIKQI-TLNYKIYKPRFFIVDF------TKVQHELIHMSNEKYRIT-LMRRS--FYRIAQQLAIKYKMNSLICGDSLGQVAS------QTIESINTISQVCD--KMEIFRPLLTFDKVEIIEIAKQIG-------------------------------------------------------
>UniRef50_Q8YA50(111-312:400) Lmo0312 protein n=6 Tax=Bacilli RepID=Q8YA50_LISMO   E=2e-10 s/c=0.34 id=22% cov=82%
-KECITLFSGGLDSFAGSY-----YNFLNNISSDYvGYVNKAEERTYQKRLQ------------SFYRKIFSAGGSEVDIRNKYQKPKIFYFQST----RSLLYLSLAISKAISNSVKEIRMYENGIlslnpEFGRYttKTTHPKTIFLYNKLLDT-LGYDIRIVNKFEYETKGEIVE--NMNLEFKSQIKNTFTCGKSRVGKeynhtgQCGACIPCILRKISLAAY------------------
>UniRef50_A8M9I7(181-346:416) Thiamine biosynthesis/tRNA modification protein ThiI n=1 Tax=Caldivirga maquilingensis IC-167 RepID=A8M9I7_CALMQ  E=2e-10 s/c=0.41 id=18% cov=64%
--KVLALVSGGFDSPVAYWLMSRRGALVDALF------------------CSLAPPVDVIGLIRVIRYLYENWVFgyDPLIMIADCTQLVNAMRSSVNSHlMNTVFkkflYRLAESIAVEGGYMGIVTGESLGQVSS---------QTLSNLYSASAGINVPIFRPLIGMDKDDIIKLAKRIG-------------------------------------------------------
>UniRef50_Q2NHQ5(177-333:384) ThiI n=1 Tax=Methanosphaera stadtmanae DSM 3091 RepID=Q2NHQ5_METST   E=2e-10 s/c=0.43 id=19% cov=67%
---VVCLISSGIDSPVASFQMLKRGCKIILLHCDNNPYTKNTIEKVKKQAQRL--QRYSVGVKVKLYTINFGQYLEHVIKQAPPRM-------TCVLCKSG-MYQTAAQLAKFNHANAIADGSSIGQVAS------QTLRNIEATRYKC---RMPIFSPLISLDKIEIEAIAKTIG-------------------------------------------------------
>UniRef50_C5EME3(23-177:273) Asparagine synthase n=4 Tax=Bacteria RepID=C5EME3_9FIRM   E=4e-10 s/c=0.43 id=37% cov=25%
-------FSGGVDSSLLLKVAAdaavETGKKVYAVTFDSRLHPSCDLEIARRVAGELGGI-HQVIEVD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1B2I0(16-171:261) Queuosine synthesis-like protein n=2 Tax=Campylobacterales RepID=D1B2I0_SULD5  E=5e-10 s/c=0.43 id=33% cov=31%
-ERLIVAFSGGVDSSFLLKTAYDvLGENVLAISLQTPYIAESEIEEARRIADEIGAR-HLVLVKPWMEELRTNP--------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C7GYX9(201-352:397) Thiamine biosynthesis/tRNA modification protein ThiI n=1 Tax=Eubacterium saphenum ATCC 49989 RepID=C7GYX9_9FIRM  E=5e-10 s/c=0.44 id=21% cov=63%
-----------IDSPVAGFLMARRGMSISAVHFNsYPYTSKRALDKVMRLKDQL-------AEYVGNFDVRTVNLLPAQMAIRSKAPENEG---TILTRR--FMIRIANIIAEEVHANALITGESLGQVAS---------QTAESLAVTDAAANLPILRPLIAYDKRDIIGIAKDIG-------------------------------------------------------
>UniRef50_UPI0001C41AAB(18-172:359) PP-loop family protein n=1 Tax=Methanobrevibacter ruminantium M1 RepID=UPI0001C41AAB  E=5e-10 s/c=0.43 id=26% cov=28%
-KKIALAFSAGADSTLLAYLAKESDCDVLAITYDNQIFPEGFLEFAKRRADELGIK-HEIIENSFL---------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_UPI000197B781(15-216:361) hypothetical protein BACCOPRO_02286 n=1 Tax=Bacteroides coprophilus DSM 18228 RepID=UPI000197B781  E=6e-10 s/c=0.33 id=25% cov=75%
--KVLLGMSGGTDSSVAAMLLQDAGYEVTGITFrFYEKDFQTEyLEDARHLCEQLGIR-HLTYDAREVF----------EEQIIHYFIQEYMNGRTPVPctlCNNQLKWPLLKEIADREGIYHLATGHYVrkqtvngrwfIRSGADPDKDQSFF-----LWGLPQDLLERALFPMGELTKVRVREIAAERGQLKAAR----------KRDSLGVC-------------------------------
>UniRef50_A6KZ28(9-197:351) tRNA-specific 2-thiouridylase mnmA 2 n=10 Tax=Bacteroides RepID=MNMA2_BACV8  E=7e-10 s/c=0.35 id=28% cov=25%
--KVLLGMSGGTDSSVAALLLQDAGYEVTGITFrFYEKENDTEyLEDARALCERLNI-PHL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C9L0F1(6-183:365) tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase n=1 Tax=Bacteroides finegoldii DSM 17565 RepID=C9L0F1_9BACE  E=9e-10 s/c=0.37 id=36% cov=24%
-RRVLLGMSGGTDSSVAAMRLLEGGYEVTGITFrFYELNDSTEyLEDARSLAERLGIR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C2BDE5(205-356:405) Thiamine biosynthesis protein n=1 Tax=Anaerococcus lactolyticus ATCC 51172 RepID=C2BDE5_9FIRM  E=9e-10 s/c=0.43 id=18% cov=63%
-----------IDSPVAGFMVAKRGMKIDCLHFHsYPFTSKRALQKAIDLAEIMSAYtgKMRVYSVNLANIYKA------------INQNCERRETTILSRR--FMMRIANKISEANGYQALITGESLGQVAS---------QTIESVAVINDSSDLPILRPLIAMDKKDIIDISLKIGSYD----------------------------------------------------
>UniRef50_B8D0L5(192-340:396) Probable tRNA sulfurtransferase n=4 Tax=Clostridia RepID=THII_HALOH   E=1e-09 s/c=0.44 id=18% cov=61%
-----------IDSPVAGWLAMKRGIELEALYFHsfpYTSDRAKEkvIDLTKVLSRYCKKIKLYV-----------GYFTDIQRAIQENCPQKY-----YITIMRRMMYRMAERIARKNGDLVLITGESVGQVAS------QTLESMNV---INEVTNMPVLRPLATMNKTEIMDLAREIG-------------------------------------------------------
>UniRef50_C9LN41(5-64:350) tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase n=1 Tax=Dialister invisus DSM 15470 RepID=C9LN41_9FIRM  E=1e-09 s/c=1.09 id=35% cov=26%
-KKVVVAMSGGVDSTLTARLLQEAGYDVYGATMN--QFDGQDMTEAQKIADFLGI-PHKVIDV------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B1I677(1-201:343) tRNA-specific 2-thiouridylase mnmA n=1 Tax=Candidatus Desulforudis audaxviator MP104C RepID=MNMA_DESAP  E=1e-09 s/c=0.32 id=34% cov=28%
MATVAVALSGGVDSSTTALLMKEAGHRVFTLTMATNDRVAAE---AARVSAFLGL-PHHVLDISGLFE-------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A7ZC18(19-156:257) Putative uncharacterized protein n=2 Tax=Campylobacter RepID=A7ZC18_CAMC1  E=1e-09 s/c=0.47 id=25% cov=60%
-----VAFSGGVDSSLLLKVAADvLGENALALTVKSPYMSLREIDEAVEFTKFYGIR-HEIFEVGIVDEIKLNP------------QNRCYLCKKAVFSR-------LIARANELGFTNLADGTNKDDLGEY---RPG-LKAKEEL---------SVLSPLINLRKFEIRELSREL--------------------------------------------------------
>UniRef50_Q5L8X6(6-115:362) tRNA-specific 2-thiouridylase mnmA 3 n=6 Tax=Bacteroides RepID=MNMA3_BACFN  E=1e-09 s/c=0.59 id=40% cov=25%
-KRVLVGMSGGIDSTATCLMLQEQGYEIVGVTMRV---WGDEPQDARELAARMGIE-HYVAD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q3Z8D8(8-185:357) tRNA-specific 2-thiouridylase mnmA n=5 Tax=Dehalococcoides RepID=MNMA_DEHE1  E=1e-09 s/c=0.37 id=37% cov=26%
----MVAMSGGVDSSVAAMLLLEQGYDVAGVSLQlksnnepYGNGYNlKLINRAREVAAALGI-PHYVVDLS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q2LUY4(47-187:296) GMP synthase (Glutamine-hydrolyzing) n=21 Tax=Bacteria RepID=Q2LUY4_SYNAS  E=2e-09 s/c=0.46 id=28% cov=60%
-----VAFSGGVDSTFLLWAAREAlGDSVTALTASAPYMPKEEICEAGRIAETIGVR-HAVLEIPLNEEIRFNP------DDRCFRCKRQ-------------LFSAMKAEADQRGIPSVLDGSNLDDL---QDYRPG-MKALKEL---------KVPSPLLEqrWRKKEIRKIGREIG-------------------------------------------------------
>UniRef50_C0E8G4(1-182:352) Putative uncharacterized protein n=1 Tax=Clostridium methylpentosum DSM 5476 RepID=C0E8G4_9CLOT  E=2e-09 s/c=0.36 id=22% cov=70%
--------SGGVDSSVAAALLIEQGYEVVGATFRLWKPEDdlfdseatccslDDINDAREVCHQLGI-PHYVLN---LKREFKEAVVQNFVE----EYQAGRTPNPCIVCNQKIKFDYFYQKAAALGFDYVATGHYArieqNEQGEFQLKTAAYAQKDQSYFLYGIPYPNlgHILFPLGGYTKPQVRELAEKYG-------------------------------------------------------
>UniRef50_B3JKC8(6-194:353) Putative uncharacterized protein n=2 Tax=Bacteroides RepID=B3JKC8_9BACE  E=2e-09 s/c=0.34 id=33% cov=23%
--KVLLGMSGGTDSSVAALLLQDAGYEVTGVTFrFYEKDNNTEyLDDARELCERLHI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C1A7G2(10-190:381) tRNA-specific 2-thiouridylase MnmA n=1 Tax=Gemmatimonas aurantiaca T-27 RepID=C1A7G2_GEMAT  E=3e-09 s/c=0.36 id=26% cov=71%
--RVLVAMSGGVDSSVAAAILMEHGCDVVGVTMklhgdgaDVPDRPCCSLDAtsdARRVCEKLGI-PHYVTNL--VDHFSHDVLDDFVQEYARGRTPIPCVRcNTFTKFRDLL------HKADAIDAPWLATGHYA--RIGHRHGQAVMVRGLDTSKDQsyflwGIDRPVldRLVLPIGAQTKAETRDIARRFG-------------------------------------------------------
>UniRef50_Q6L1T4(171-325:469) Hypothetical thiamine biosynthesis protein thiI n=1 Tax=Picrophilus torridus RepID=Q6L1T4_PICTO  E=3e-09 s/c=0.41 id=20% cov=65%
---ALSLFSGGNDSPLATYMVMKRGSPCDLLfcSFAHPEDTYNMLLSARRLFDKYS------YGYDPLIYIIDGTELASRIMERNQKYGNLIFKK--------LLYLYADNLCSLKNYNAMVTGESIGQVSS---------QTLENLRSLSHGIDHPILRPLIGFDKDEIVSKSRELG-------------------------------------------------------
>UniRef50_D1PFA3(147-385:473) Putative uncharacterized protein n=2 Tax=Bacteroidales RepID=D1PFA3_9BACT  E=3e-09 s/c=0.27 id=18% cov=84%
----VALFSGGLDSLIGFI------DETNTLSVNKKILLVSHMELGKEHCDQKSILG-YCRENNIFQNKFEQVLLNAGLKPKSWNVKGTPSESTF-RSRSLLFFAAGIYVAHKMSPNTplIVpeNGTISINIPldsgrrsacSTRTTHPTFIKRIQEALQL-VGINNTFYNPYRLKSKADMMKDCDndvnKSVILRQLYSKSCSCakrghnshwdkpgdvIRNKKITHCGMCLPCLYRR------------------------
>UniRef50_C7NS92(191-346:407) Thiamine biosynthesis protein n=2 Tax=Halobacteriaceae RepID=C7NS92_HALUD  E=4e-09 s/c=0.41 id=20% cov=63%
----VALISGGIDSPVAAWQVMTRGAPVVPVYVDLG---------------DYGGVDHRARAETTVAALARRAPNfDLRLRVLDGGKAVEELVAETDDTRmlslRRFMYRAAETVAREHDAVGIVSGEAIGQKSS------------QTTANIAATDGVtdlPIHRPLLTMDKTDIIEAARDL--------------------------------------------------------
>UniRef50_A8AAD7(47-161:383) PP-loop domain protein n=1 Tax=Ignicoccus hospitalis KIN4/I RepID=A8AAD7_IGNH4  E=4e-09 s/c=0.55 id=30% cov=26%
-KRVLLGLSGGKDSVALLYLLKKVGTEVVAATVDTVPNYTSlEAELAKRVAEELGVTHYTV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C6CRM5(27-188:475) tRNA(Ile)-lysidine synthetase n=1 Tax=Paenibacillus sp. JDR-2 RepID=C6CRM5_PAESJ  E=1e-08 s/c=0.39 id=34% cov=27%
--RIVAAVSGGPDSMALLHLlwqaARQEQLTVIAAHVNHGFRkdaSRQEAEVVRQYAEKLGV-PFEMIELD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q47BM0(4-71:468) Argininosuccinate synthase n=58 Tax=cellular organisms RepID=ASSY_DECAR  E=1e-08 s/c=0.91 id=38% cov=24%
IKKVVLAYSGGLDTSVILKWLQDVYkCEVVTFTADLGQ--GEELEPARAKALKAGIKP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A5USZ2(29-184:285) ExsB family protein n=5 Tax=cellular organisms RepID=A5USZ2_ROSS1   E=2e-08 s/c=0.39 id=29% cov=62%
---ALIAFSGGVDSTLLLKVAHDTlGDRAIAATADSETYPREELEQACALAALIGCR-HIVVRTDELS---------------DERYARNHPDRCYYCKRT--LFTHLQPLAAELGVAAILYGAMADDIG---DHRPGLRAAVEFAVR----------SPLIeaGLGKREIRELARRLG-------------------------------------------------------
>UniRef50_B6VWC2(147-381:471) Putative uncharacterized protein n=2 Tax=Bacteroidales RepID=B6VWC2_9BACE  E=2e-08 s/c=0.26 id=19% cov=85%
----VALFSGGLDSLIGFI------DEASTLSVD------KKI----LLVSHMELGKEHSDQKSILKYCRENNIFSNKYEQvllnAGLKPHSWNIKtPTESTFRSRSLLFFAAGIYivnkISPQCQLIVpeNGTISINIPldsgrrsscSTRTTHPTFIKRIQEAL-YAIGISNSIYNPYRLKSKADMVLECCQDTSkkaiLKSLVDLSCSCakrghnvfwdksgieIRNAKIKHCGMCLPCLYRRVALDTIGLDN--------------
>UniRef50_B8G2C3(15-162:267) ExsB family protein n=4 Tax=Clostridia RepID=B8G2C3_DESHD   E=3e-08 s/c=0.41 id=26% cov=63%
MEAVVVAFSGGVDSTFLLKVAHETlGDHCLAVIGASETMPSADYNNALQQAKEFGAKFLVIETEEMGKEEFV-----KNPQNRCFHCKNE-------------LFTKLLGIAQEKKINWVLDGSNADDLK---DYRPG----MQAARALG------IRSPLqeAGLSKEEIRQLSKKMG-------------------------------------------------------
>UniRef50_Q1NYA2(76-252:443) TRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase n=3 Tax=Deltaproteobacteria RepID=Q1NYA2_9DELT  E=4e-08 s/c=0.34 id=21% cov=71%
-RQVAVAMSGGVDSSVTAALLQQAGAEVRGVFMRLAQPEvEAHRQRAAAVADFLGIELTVLDLAQPFRQQVLNPFVEAYLAGLTPNPCVFCNRLIKFGLLLEILLAqgvelLATGHYVRLlpaatGGRRLCRGLDPGKDQSYFLCR------------LAAEKLPRLLFPLGDKHKSEVYQLAARLG-------------------------------------------------------
>UniRef50_B9L801(3-172:341) tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase n=1 Tax=Nautilia profundicola AmH RepID=B9L801_NAUPA  E=5e-08 s/c=0.35 id=21% cov=69%
-KRVLVGVSGGVDSAMSVYLLKEQGYDVVGIYmkMHEGVNHVENVAKLNRLSKKLGFEYVIEDVEDEFRkevyEYFVESYKQGITPNPCAMCNIK------------IKFGIFMGFLEKYGCELAATGHYVRNDGEFlyqaKDQSKD-----QSYFLFGIKKKVlpKILFPLGEYTKDEIKKLASEIG-------------------------------------------------------
>UniRef50_C0GFP8(206-263:483) Asparagine synthase n=1 Tax=Dethiobacter alkaliphilus AHT 1 RepID=C0GFP8_9FIRM  E=5e-08 s/c=1.04 id=29% cov=25%
-----VALSGGLDSSIILAVAREFDKDIAAFTATFAERHGEDLEYAKLLADQLGV-DHHIYEI------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_P59606(4-64:401) Argininosuccinate synthase n=22 Tax=Proteobacteria RepID=ASSY_XYLFT  E=7e-08 s/c=0.98 id=34% cov=27%
-KNIVLAFSGGLDTSFCIPYLKEQGYAVHTVFADTGGVDEDERDFIEKRAAELGVASHLTVD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B9CYH7(19-157:260) Putative uncharacterized protein n=3 Tax=Campylobacter RepID=B9CYH7_WOLRE  E=7e-08 s/c=0.43 id=25% cov=60%
-----VAFSGGADSSLLLRAAHgALDARAIGITIRSPYMSSREIAEAVEFARAYGIR-HEILELGVAEGIKNNP------------ENRCYLCKKAVFSR-------LIERARELGFSRVADGTNRDDLGEY---RPG-LKAKEEL---------GVLSPLINLTKSEIRELSRELG-------------------------------------------------------
>UniRef50_B3DUT9(13-194:367) tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase n=1 Tax=Methylacidiphilum infernorum V4 RepID=B3DUT9_METI4  E=1e-07 s/c=0.33 id=25% cov=71%
--RIVVGMSGGVDSTVAAYLLKREGFDVVGITLkiwtDRCMHISSEkccgpdaINDARNMAAQIGIPHYVLDEADCFEKEVISYFLReyslGRTPNPCVKCNEKikfGRLWTRVQSWGVEYLATGH-YALVENQDHIPR------LKKAKDKRR---DQSYFLFSLSAGQLSRMITPLGNLEKKEVRAIAKEAG-------------------------------------------------------
>UniRef50_B2IGB5(83-244:400) tRNA(Ile)-lysidine synthetase n=2 Tax=Beijerinckiaceae RepID=B2IGB5_BEII9  E=1e-07 s/c=0.37 id=24% cov=45%
-RKVLLAVSGGPDSVALMLLAAQwaeavwKAPPLSVASVDHGLRPDSlaEAEQVAEWAARLGLPHHI------LRWEGEKPKTRLQERARDARYG------------------LLIAHAETIGADYLVTAHHADD--------------------------------------------------------------------------------------------------------
>UniRef50_A5TXN2(9-171:337) tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase n=16 Tax=Fusobacterium RepID=A5TXN2_FUSNP  E=1e-07 s/c=0.36 id=33% cov=22%
--KALALFSGGLDSALAIKVVQEQGIEVIAlnfVSHFFGGKN----EKAESMAKQLGIR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D0NFB6(229-389:665) tRNA(Ile)-lysidine synthase, putative n=1 Tax=Phytophthora infestans T30-4 RepID=D0NFB6_PHYIN  E=1e-07 s/c=0.37 id=21% cov=63%
-----VSLSGGVDSMVVAYLMHKLKEKhgdftIVAVHLDYGNRPESgaECDYVRRWCERFGIVFH-VRRIDEVKR-----ATTRRDDYEKIS--REIRYSTY------------AEVMQKYHIPGMCFGHHRGDVQ------ENVISNMmkglsllnlNGMQASSVVNGVRIWRPLLDLEKDVIFEFAHRYG-------------------------------------------------------
>UniRef50_UPI0001789086(29-191:476) tRNA(Ile)-lysidine synthetase n=1 Tax=Geobacillus sp. Y412MC10 RepID=UPI0001789086  E=1e-07 s/c=0.36 id=26% cov=64%
----VVAVSGGPDSVALLHVLHEISqhrtpLRLICAHVHHGFRkeSDQEAEMVRELAESLGL-----------------PLETAFIDIPAYMEESGKGGQEAAREKRYEFL---LQTARKHNARSVALAHHADDQA-----ETVFMRLLRGSGLSGlggikfkrTEKKVELIRPFLRMYKADIVELCRVCG-------------------------------------------------------
>UniRef50_D2LA41(19-162:272) ExsB family protein n=2 Tax=Desulfovibrio RepID=D2LA41_9DELT   E=1e-07 s/c=0.41 id=40% cov=25%
---VLVAFSGGTDSTLVLRAVLDAlpGENVLAVTLAAPYTPAFEVAAAREAAKSMGAR-HEV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A4X6Q9(230-403:536) Asparagine synthase (Glutamine-hydrolyzing) n=3 Tax=Micromonosporaceae RepID=A4X6Q9_SALTO  E=1e-07 s/c=0.34 id=36% cov=24%
-----VVLSGGLDSSLALLHARELHPDCVAVTV--GVPESPDLLYARRLAKDLGV-PHEVVEL------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A0LH52(27-183:276) PP-loop domain protein n=1 Tax=Syntrophobacter fumaroxidans MPOB RepID=A0LH52_SYNFM  E=1e-07 s/c=0.37 id=23% cov=46%
-------FSGGVDSSLLAWFAHAWLKKKVFVFFAeSGFASGSDRRNAARVAEEIGL-PLEIVPVDVFSIEA----LRDNHPRRCYFCKKE-------------MLSRIRMKAAESGCDILFDGSHAGDALGY----------------------------------------------------------------------------------------------------
>UniRef50_Q2SSN7(177-334:395) Thiamine biosynthesis protein ThiI n=5 Tax=Mollicutes RepID=Q2SSN7_MYCCT  E=1e-07 s/c=0.37 id=22% cov=64%
--KGLCLLSGGIDSPVSAFLTLKRGMQVDFIHFmtpphTSHQALDKVFSLARQLAK-YNISNFKLHICNFNLLLQE-----------LQHLVDPSYKIT-IMRR--MFLRIANIIAKNNNNKAIITGESLGQVAS------QTIQSINVINNVS---DLPILRPVITYDKEEIIKIAK----------------------------------------------------------
>UniRef50_C0QG63(32-202:365) tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase n=1 Tax=Desulfobacterium autotrophicum HRM2 RepID=C0QG63_DESAH  E=1e-07 s/c=0.34 id=26% cov=44%
--------SGGIDSLVAAHVLKRQGHDLVGIHFTTGF--ESEAVDLSSIEDQLDIKIHQMDLSAEFNravvDYFVKTYARGKTPNPC-----------VVCNRTIKF-GVLAQRAKTLGAEKIATG-------------------------------------------------------------------------------------------------------------
>UniRef50_A0B709(22-165:282) PP-loop domain protein n=1 Tax=Methanosaeta thermophila PT RepID=A0B709_METTP  E=2e-07 s/c=0.41 id=26% cov=48%
----LVSFSGGVDSSLLAAISRDvLGDGAVAVILDSPLMPRRELEHATSVAQLLGIRC-IVAVHDVFELES----VIENSPERCYHCKKSSA-------------GILKKLANSLGISCVADGVNTTD---YEDFRP-----------------------------------------------------------------------------------------------
>UniRef50_B8I8Q7(20-164:269) ExsB family protein n=5 Tax=Bacteria RepID=B8I8Q7_CLOCE   E=2e-07 s/c=0.40 id=32% cov=27%
---AAVAFSGGVDSSLLLKVAYDvLGNGVVAVTAHSSTYPEREMNEAKEFTANYGIK-HRIIDSDEL---------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A4J0U7(19-164:270) PP-loop domain protein n=4 Tax=Firmicutes RepID=A4J0U7_DESRM   E=2e-07 s/c=0.40 id=36% cov=26%
--KVLVAYSGGTDSAFLLAVAVQElGDNVLAVTAISPTSTKAEVAEAQQLAKELGVH-HRII--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q0F280(23-247:374) TRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase n=1 Tax=Mariprofundus ferrooxydans PV-1 RepID=Q0F280_9PROT  E=2e-07 s/c=0.26 id=24% cov=70%
--RVIAAMSGGVDSSVMAVLLKEAGVDVIGVFLNVWDYSRDEVNrhgsccsledsyDARRVADHIGIPFYAMDMRDEFRRDVIDPFIQDYETGRTPNPCERC-------NRFVKFGALLEA-ADKLEAAYVATGHYvrrRDDNDGIHlfkgnDARKDqsyFLATTNRA------QAERILFPVGGLEKDDTRRLAHFYK-------------------------------------------------------
>UniRef50_Q3SP27(38-193:371) tRNA(Ile)-lysidine synthase n=2 Tax=Bradyrhizobiaceae RepID=Q3SP27_NITWN  E=2e-07 s/c=0.37 id=32% cov=25%
--RALVLaVSGGPDSVALMWLaarwrrAMKRGPDLVAVTVDHALRreAAREARQVKQLAKSLSI-PHR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A9CZX4(59-173:360) Putative LPS biosynthesis protein WbpG n=1 Tax=Hoeflea phototrophica DFL-43 RepID=A9CZX4_9RHIZ  E=2e-07 s/c=0.50 id=27% cov=46%
----VIGVSGGVDSTYVAWLVKKLGLRPLAVHLDNGWNSELAVANIEKTLNTLGIDLYtHVLNWEEFRNLQSSFL---KASTPDGE----------VPTDHAIF-ALLYELAAKHGLKHVITGTN-----------------------------------------------------------------------------------------------------------
>UniRef50_D1BMR1(15-158:248) ExsB family protein n=7 Tax=Clostridiales RepID=D1BMR1_VEIPT   E=7e-07 s/c=0.39 id=25% cov=26%
-----VALSGGVDSSYLAYAAKQSGIPCKAYTVKSQFVPQFELNDAKKIAEFIDI-PLKIIDIDVL---------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6DKP8(211-386:598) Bifunctional GMP synthase/glutamine amidotransferase protein n=1 Tax=Lentisphaera araneosa HTCC2155 RepID=A6DKP8_9BACT  E=7e-07 s/c=0.32 id=21% cov=69%
-KKVFLLVSGGVDSNVAFALLnKALGDEnVYGLHVDNGLMRKDESAWVKEELKQAGFSNFHVVD-------AGDTFLKNLAGVSEPQAKRVIIGDTFL-----------DVKCEAVEESDLVdDSWLLGQGTIYPDtiesggtenshlikTHHNRVDRIQELINQG-----KVIEPLAELYKDEVRELGEL---LGLPHKLVW---------------------------------------------
>UniRef50_C5A633(9-148:206) ATPase, putative, PP-loop superfamily n=7 Tax=Thermococcaceae RepID=C5A633_THEGJ  E=9e-07 s/c=0.40 id=36% cov=24%
------LYSGGKDSSLAAWILSQLGYEVELVTVTFGLLDN--WRYARETAERLGF-PHRVLELP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B9K6T2(72-188:327) PP-loop domain protein n=7 Tax=Thermotogaceae RepID=B9K6T2_THENN   E=1e-06 s/c=0.48 id=25% cov=24%
--KILIAVSGGKDSVSLWHMLKKLGYEVDALFIRAGrsgmvQKAQ---EIVEKNAELLGTKLHIV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q3AD57(1-214:338) Putative uncharacterized protein n=1 Tax=Carboxydothermus hydrogenoformans Z-2901 RepID=Q3AD57_CARHZ  E=1e-06 s/c=0.26 id=22% cov=81%
MVKALALFSGGLDSTLAIKLILEQGVEVEAVNFTSPFCRclakGQGCASTAKLAADLGIKLH-------VQNCGEEYL--RIVENPPHGYGSALNPC--IDCRIFKF-KKAKKLMEEIGAKFMITGEVLGQRPNSQ--RRDAINLIDR------EAGIKglVLRPLSALhfpptiaeqegyvSRDKLLAISGRSRKTQMELAASF----GINDYPCPS-GGCLLTKKEF---------------------
>UniRef50_Q4BY27(312-436:542) Asparagine synthase (Glutamine-hydrolyzing) n=1 Tax=Crocosphaera watsonii WH 8501 RepID=Q4BY27_CROWT  E=1e-06 s/c=0.45 id=29% cov=21%
-----VYLSGGLDSSCVTALAKQFHQEtVHTYSIHFGEDYPNELEFSSLVAAH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6FY47(28-171:277) Putative uncharacterized protein n=1 Tax=Plesiocystis pacifica SIR-1 RepID=A6FY47_9DELT  E=2e-06 s/c=0.38 id=27% cov=61%
----VTAFSGGVDSTLVAVVAARvHGERALAVTGVSPSLAESERAFASRVAAELGLR-HRLVDTHEIERAGYQANAGDR----CYHCKTELFERLVV-------------LAKAEGFACVVSGDNLDDLGGH---RPGMLAAEENAVRK----------PLIeaELGKDQIRALARHLG-------------------------------------------------------
>UniRef50_Q5NLX8(34-189:329) tRNA(Ile)-lysidine synthase n=3 Tax=Zymomonas mobilis RepID=TILS_ZYMMO  E=2e-06 s/c=0.35 id=30% cov=23%
-------VSGGSDSLALLLLGAVSDFPVEAVTVDHGMRpeAAEEARFVAQICQQIGV-PHQIL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q5SH30(38-185:281) NH(3)-dependent NAD(+) synthetase n=3 Tax=Thermus RepID=Q5SH30_THET8  E=2e-06 s/c=0.37 id=25% cov=63%
-EKAIVAVSGGVDSATTLALAVRAlgAERVHALFLPHRESSPTSREHAYLVAETFGVALEEVDITPMVE--GYAALTPDLTPHRKGNVMA--------RARMIVLFDKSEAYrALPLG-----TGNKTERLFGY-------------FTWHGDDTPP--VNPLGDLYKTQVWRLAEHLG-------------------------------------------------------
>UniRef50_Q83CD9(191-337:392) Probable tRNA sulfurtransferase n=5 Tax=Coxiella burnetii RepID=THII_COXBU  E=3e-06 s/c=0.37 id=20% cov=61%
-----------IDSPVAGWTLLKRGMMIDAVYFHSfpytGEKAKeKVIDLARVLTSwKLRAINLHIPYFTKIQET----------------VNKMCPESTWTIIHRRFMMRIAEKLTKST-YHTLITGENLGQVAS---------QTIQNIAVINQATNLPILRPLISFDKNDIIKIAEKIG-------------------------------------------------------
>UniRef50_C4Z434(22-174:486) Cell cycle protein MesJ n=1 Tax=Eubacterium eligens ATCC 27750 RepID=C4Z434_EUBE2  E=3e-06 s/c=0.35 id=36% cov=24%
-ERVVVGLSGGADS-VCLLMVLKGYIerrrlqtELCAVHVNHGirQEAGDDEEFARALCERMGVE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A4FWT9(22-173:258) PP-loop domain protein n=5 Tax=Methanococcus RepID=A4FWT9_METM5   E=4e-06 s/c=0.35 id=31% cov=31%
-KKVIVAYSGGVDSTLISKIASDA-TKTLAVTVDNGFFSENVIKKAEDCAKKYNI-PQKTEKIDYLNEITSKNL-------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B8I0Z1(69-191:355) Putative uncharacterized protein n=1 Tax=Clostridium cellulolyticum H10 RepID=B8I0Z1_CLOCE  E=5e-06 s/c=0.44 id=26% cov=26%
----LVMLSGGKDSIYVAYILSKVYKlNIVGLTIDNGFEYQSTFDNSYDIAKKLGI-SHFIYRLPF----------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q12V31(23-182:263) NH(3)-dependent NAD(+) synthetase n=1 Tax=Methanococcoides burtonii DSM 6242 RepID=NADE_METBU  E=5e-06 s/c=0.34 id=27% cov=31%
---AVVGISGGIDSALVAYLSVEAlgAENVLGIHMPEASTPKSEIEDASKVAEALGI-DFKVINITNVLEVYRTAM-------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6CDN2(21-181:287) Putative uncharacterized protein n=1 Tax=Planctomyces maris DSM 8797 RepID=A6CDN2_9PLAN  E=6e-06 s/c=0.33 id=24% cov=64%
MDRIIVAFSAGVDSTVVAqAAFLARGDHAQAATAVSPSLASGEKEEAIHLAELIGI-PHRLV-------------TTSEFATEEYRANAPNRCFFCKTELYQILSQSIAGTAWET--ATLVNGANLDDRG---DHRPG----MQAASNY------HVRSPLIeaEFTKEEVRALARHW--------------------------------------------------------
>UniRef50_C8WLL2(6-211:352) tRNA(5-methylaminomethyl-2-thiouridylate)-methyl transferase n=1 Tax=Eggerthella lenta DSM 2243 RepID=C8WLL2_EGGLE  E=6e-06 s/c=0.26 id=24% cov=80%
--------SGGVDSAVSAALLMRAGYEVVGVTcrFRDNAATERAAADAAAVCSQLGIRHEAPGCVGEFERCvvepFVSSYAAGLTPSPCVGCNARCKMPALV------------RVAGELGCDRIATGHYARIARLSDSGRFVVKRALDArkdqsyMLSLLSQEQLaRLVLPLGAMTKAEVRVIAADLGLVVAEKAESQdNCFIEGDYRP-------FLRARGVE--------------------
>UniRef50_C9YDI6(264-378:647) Putative uncharacterized protein n=1 Tax=Curvibacter putative symbiont of Hydra magnipapillata RepID=C9YDI6_9BURK  E=6e-06 s/c=0.46 id=33% cov=22%
-------LSGGLDSSAVVAFAREQNPDIQCYSIDV-QGAQDEgfaddLPYARRVAQHLGVPLH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C5RD28(26-188:324) Possible tRNA(Ile)-lysidine synthetase MesJ n=1 Tax=Weissella paramesenteroides ATCC 33313 RepID=C5RD28_WEIPA  E=7e-06 s/c=0.33 id=24% cov=45%
---VLVAVSGGQDSLRLLRWLtagdlpKDLQPQVSAIYINHQLRsdAQQEEALVRKVFAH---TPHL--QSATIRKLDWS-------EVPTVSVEEKAREK-----RYGVMFSV----AEQVGANSIVTAHHRND--------------------------------------------------------------------------------------------------------
>UniRef50_C0W8C3(193-288:549) Putative uncharacterized protein n=1 Tax=Actinomyces urogenitalis DSM 15434 RepID=C0W8C3_9ACTO  E=9e-06 s/c=0.55 id=31% cov=26%
--RLVIPLSGGLDSRLLVAWlaLHDQIRPGRALAFTYGVPGAREVEVSRQVAQQVGLEWHTV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B9XSJ6(20-163:275) ExsB family protein n=1 Tax=bacterium Ellin514 RepID=B9XSJ6_9BACT   E=9e-06 s/c=0.37 id=25% cov=25%
----LVAYSGGVDSVFLAKVAKDvLGKKSLAAIADSPSLPRRELEEALEIARRFEIPVRIV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A3LTD8(25-198:484) Predicted protein n=1 Tax=Pichia stipitis RepID=A3LTD8_PICST   E=1e-05 s/c=0.30 id=39% cov=25%
--RVLVALSGGVDS-ICLTYLLSQYSRLYcnnaiainAITIDHGYRsgSNEEAKAVGKLVEKWGV-QHIV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A8ACB5(32-129:275) NH(3)-dependent NAD(+) synthetase n=1 Tax=Ignicoccus hospitalis KIN4/I RepID=A8ACB5_IGNH4  E=1e-05 s/c=0.54 id=25% cov=26%
---AVIGLSGGVDSAVTAALLSEALgpERVRALILPSASTPEKDVEDAKRVARLLGIEDVRVIDV------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q2NHY4(53-174:319) Predicted ATPase n=5 Tax=Methanobacteriaceae RepID=Q2NHY4_METST   E=1e-05 s/c=0.43 id=34% cov=26%
--KVLVGLSGGKDSVALLKILnilkEKNIITLEAVTIDEGiSGYREEgIRIAKETAKALDIKHHIV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A1VRZ2(71-185:380) LPS biosynthesis protein WbpG n=6 Tax=Proteobacteria RepID=A1VRZ2_POLNA  E=1e-05 s/c=0.45 id=23% cov=48%
-------LSGGVDSSYLALKVHERGLRPLVVHVDAGWNSELAVANIEKIVKFCDFDLHtHVVDWEEMRDLQLAFL-------------RSGIANQDVPQDHIFFASIYH-YATKHGIKYVLSGGNLATEGIYP---------------------------------------------------------------------------------------------------
>UniRef50_Q2GC97(27-184:326) tRNA(Ile)-lysidine synthase n=1 Tax=Novosphingobium aromaticivorans DSM 12444 RepID=TILS_NOVAD  E=1e-05 s/c=0.33 id=24% cov=65%
--RVCLAVSGGPDSLALMLLMQEVAPRDFCVaTVDHGLRAESAAEAAmvAGLCEMRGIAYHTLR----LDLAGGSAVQERARKAR---------------------YAALADLARRDGLSAVVTAHHADDQAetlVMRLNRGAGLRglaGMRAASSVPGAGEVRLLRPLLGWRRAELVALVEDAG-------------------------------------------------------
>UniRef50_C6A5B5(27-181:254) NH(3)-dependent NAD(+) synthetase n=7 Tax=Thermococcaceae RepID=NADE_THESM  E=1e-05 s/c=0.34 id=21% cov=63%
-KGVILGISGGVDSATVAYLAARAigKEKVLGLVMPY--HINRDVEDALLVCNNLGINYKVINIKSIVNEFEKN-----------LDFELNNVSRGNIMSRTRMILL----YAHANSKNYLVLGTS---------NRSEFLTGYFTKWGDSASD----YAPLINLYKTEVWNIARILG-------------------------------------------------------
>UniRef50_A3PM55(21-172:412) tRNA(Ile)-lysidine synthetase n=8 Tax=Rhodobacteraceae RepID=A3PM55_RHOS1  E=1e-05 s/c=0.34 id=31% cov=21%
-------VSGGGDSMALLHLAAEAGIATRAVTVDHGLRpeAADEARAVARVCAGLGV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q8DNP8(1-51:154) NADPH-dependent 7-cyano-7-deazaguanine reductase n=26 Tax=Streptococcus pneumoniae RepID=QUEF_STRR6  E=2e-05 s/c=1.02 id=44% cov=21%
-----------------------HYETVEAVTFAYGQHHHLEIQITREIAKEQGIR-HHILDMSLLGQITA----------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B2IRJ0(21-132:156) Argininosuccinate synthase, truncation n=12 Tax=Streptococcus pneumoniae RepID=B2IRJ0_STRPS  E=2e-05 s/c=0.46 id=28% cov=26%
-EKVILAYSGGLDTSVAITWLKKD-YDVVAVCMDVG--EGKDLDFIHDKALKVGAVESYVIDV------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C1N3G9(283-455:758) Predicted protein n=1 Tax=Micromonas pusilla CCMP1545 RepID=C1N3G9_9CHLO  E=2e-05 s/c=0.30 id=23% cov=68%
-------LSGGVDSMALAVILKRlsrdasyGGFDVVAMHIDYDNRPEsgVEADFVRGWCDRMGIEC-VVRKIAEV----------TRGVTPREQYEAESRAI-----RYGFYKDVAKTHAFP----AVFVGHHEGDVQeniIANLMRGANLLAVNGMEETGVVEGVAIWRPMLPHSKAVVLDFAHKY---GVPYFLdstpTWS--------------------------------------------
>UniRef50_C5VKF6(22-128:456) tRNA(Ile)-lysidine synthetase n=2 Tax=Prevotella RepID=C5VKF6_9BACT   E=2e-05 s/c=0.48 id=25% cov=25%
----LVALSGGADSVALLLCIKELGYRVEAVHCNFhlrGEESLRDEQFCEDLCQRENIPLHKV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q0W3F0(70-150:377) Putative uncharacterized protein n=1 Tax=uncultured methanogenic archaeon RC-I RepID=Q0W3F0_UNCMA  E=2e-05 s/c=0.64 id=29% cov=25%
----VVGVSGGRDSTYVLYNAIKLGLRPLAVHFDNGWNSDIAVSNIKRATTRLNVDLHTVV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1B719(8-193:346) tRNA(5-methylaminomethyl-2-thiouridylate)-methyl transferase n=1 Tax=Thermanaerovibrio acidaminovorans DSM 6589 RepID=D1B719_THEAS  E=2e-05 s/c=0.28 id=31% cov=25%
-----VLMSGGVDSSVTAMILKGEGHRPLGVTLLMspsSSECSRSVQLARRTAEILGIR-HTVLDL------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q9X2V9(192-283:513) Microcin J25-processing protein mcjC n=1 Tax=Escherichia coli RepID=MCJC_ECOLX  E=2e-05 s/c=0.56 id=22% cov=24%
-RKIALLFSGGLDSALIFHTLKESGNKFCAYHFFSDESDDSEKYFAKEYCSKYGV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q7KTW9(246-411:558) Asparagine synthetase n=23 Tax=Diptera RepID=Q7KTW9_DROME   E=2e-05 s/c=0.31 id=27% cov=24%
------LLSGGVDSSLIASIAtkimRERDPNFRLKTFSVGLRDAPDFQAARSVAKYID-SDHKEI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C4G1X8(34-193:477) Putative uncharacterized protein n=1 Tax=Abiotrophia defectiva ATCC 49176 RepID=C4G1X8_ABIDE  E=2e-05 s/c=0.32 id=17% cov=65%
-EKIVAGVSGGADSVCLLLVLKDilNPENIVAVHINHGIRgeeAARDEEFVKKLCEKYNI-CLEIRHLSIPEYSKKHKISEEEAGRILRYEVFEEIR-------------------QEKNADKIAVAHNMNDTA------ETFLLNLSRGSGITGLTGIkisnsRIIRPLIKTSRDEIEKIAEYYGE------------------------------------------------------
>UniRef50_A8LHQ9(23-131:417) tRNA(Ile)-lysidine synthetase n=1 Tax=Dinoroseobacter shibae DFL 12 RepID=A8LHQ9_DINSH  E=2e-05 s/c=0.47 id=35% cov=24%
-RRIGVAMSGGGDSMALLHlladWAAQSGAELRAASVDHGLRpeAADEIALAAKTCAALGI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C4V3Z4(243-387:555) Possible NAD(+) synthase (Glutamine-hydrolyzing) n=2 Tax=Selenomonas RepID=C4V3Z4_9FIRM  E=3e-05 s/c=0.35 id=23% cov=48%
MERVVIGISGGIDSAVAAALYVDAIGAENVLLVNMPSRfnSATTKGLAAQLADNLG-SRHMIVPIEESVSYTAKQLSEIPIEGAAAAPGEHLTISSFVrenmQARNrsgRVLATIAAAW-------------------------------------------------------------------------------------------------------------------------
>UniRef50_C3XFK4(23-95:369) tRNA(Ile)-lysidine synthase n=1 Tax=Helicobacter bilis ATCC 43879 RepID=C3XFK4_9HELI  E=3e-05 s/c=0.70 id=31% cov=23%
--KNLLAFSGGIDSTALFFVLMEHKIEFDIAIIDYGKRSQSkdEVLYAKSLAKQY----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A8S8Y3(5-121:230) Putative uncharacterized protein n=1 Tax=Faecalibacterium prausnitzii M21/2 RepID=A8S8Y3_9FIRM  E=4e-05 s/c=0.43 id=28% cov=26%
-KKVVLAYSDGLDTSIIIPWLKEHYnnCEVIAVCGNVGQK--GELEGLEERAKASGASKLYIEDL------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q4RIX1(251-313:619) Chromosome undetermined SCAF15041, whole genome shotgun sequence. (Fragment) n=20 Tax=Deuterostomia RepID=Q4RIX1_TETNG  E=4e-05 s/c=0.80 id=28% cov=26%
-RRIGCLLSGGLDSSlvsaTLMKLAKEEKLQYPLQTFSIGSEDSPDLLAARKVAAYIGSEHHEV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A8G8L6(261-371:610) Asparagine synthase (Glutamine-hydrolyzing) n=1 Tax=Serratia proteamaculans 568 RepID=A8G8L6_SERP5  E=5e-05 s/c=0.45 id=33% cov=22%
------MLSGGLDSSLITAIACRQGRRelkTFAVGFN--ESAFSELDYSRRLAKDLGTEHH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C4QP81(27-267:312) tRNA(5-methylaminomethyl-2-thiouridylate)-methy lt ransferase,putative (Fragment) n=1 Tax=Schistosoma mansoni RepID=C4QP81_SCHMA  E=5e-05 s/c=0.21 id=21% cov=88%
--------SGGVDSAVSAYLLKKKGFQVKGVFMtNWDSLDEkidcsldKDRQDAQFVCDYLGIPFFEKNFVKEYWNYVFLPLIKSYEQ--GATPNPDILCNRFVKF---NLLTRAVlksknqcadddSQASSnLAADAIATGHYCQNSFGnYLQYRKDNVEArllrsvdrvKDQTFWLSTISHKELpycMFPVGDLLKTQVKQIAQDIG-----LSRIYS-----RRESMGMCFIGKRRFSEFIDnYLEPKPGVYKDLE------
>UniRef50_A4RU16(236-425:638) Predicted protein n=8 Tax=cellular organisms RepID=A4RU16_OSTLU   E=7e-05 s/c=0.26 id=32% cov=24%
-----VLLSGGLDSSLITsiavrqrKLAKNTYGADEPVHsFSIGIKGAPDLVAARKVAEQLGTIHHEV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C7NZZ2(10-120:424) Argininosuccinate synthase n=6 Tax=Euryarchaeota RepID=C7NZZ2_HALMD   E=7e-05 s/c=0.45 id=43% cov=23%
-------FSGGLDTTVCVSLLKEEygYDEVVGVTVDVGQ-PDYEFEEAEETAEALGVEQYVV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1NTX7(21-219:427) Argininosuccinate synthase n=1 Tax=Bifidobacterium gallicum DSM 20093 RepID=D1NTX7_9BIFI  E=7e-05 s/c=0.25 id=28% cov=26%
--RIVLAYSGGLDTSVAIPYLKDRtGKDVVAVSLDVGQGGES-LETIKERALACGAVESYIVD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C5BIC0(164-214:432) Asparagine synthase family protein n=1 Tax=Teredinibacter turnerae T7901 RepID=C5BIC0_TERTT  E=7e-05 s/c=0.98 id=36% cov=22%
-----VALSGGLDSSTMAHYAKRFCANPIAVTLDLGGSEDAE--KAQKIAAQLAIR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A1ZYT2(266-378:636) Asparagine synthase (Glutamine-hydrolyzing) n=1 Tax=Microscilla marina ATCC 23134 RepID=A1ZYT2_9SPHI  E=7e-05 s/c=0.44 id=32% cov=25%
-------LSGGIDSSVIATLAARHTDQLHTFSIGYkDEPFFDETNYAQLVAKKIGAK-HTVFSVS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C1E2C8(22-98:204) Predicted protein (Fragment) n=2 Tax=Micromonas RepID=C1E2C8_9CHLO  E=8e-05 s/c=0.64 id=35% cov=25%
--RVVLCVSGGVDSVALLHLMVELRQEwaldLHILHFNHGKRAesREEEAFVKDLGAKLGVEVH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A7HV06(31-195:443) tRNA(Ile)-lysidine synthetase n=1 Tax=Parvibaculum lavamentivorans DS-1 RepID=A7HV06_PARL1  E=8e-05 s/c=0.30 id=34% cov=25%
-KKIAIAFSGGPDSLALLILAaewakKRRGISLVAFTVDHGLRaaSAAEAKAAARLSDELGV-PHR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D0GMM0(25-176:307) tRNA(Ile)-lysidine synthase n=1 Tax=Leptotrichia goodfellowii F0264 RepID=D0GMM0_9FUSO  E=8e-05 s/c=0.33 id=24% cov=23%
--KILLAFSGGPDSVFLyriLSFFQEKYSlELALMYVNHNLRHDVEkdLEFVKRFSEENGV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A0B6P2(50-170:326) PP-loop domain protein n=1 Tax=Methanosaeta thermophila PT RepID=A0B6P2_METTP  E=0.0001 s/c=0.41 id=27% cov=29%
--RVAVALSGGKDSSVLLYTLKrifshRRDIELIALMVDEGISGYREdtLQNAAALADRLDV-PHI--TLSFREEFG-----------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q8TXB8(8-107:334) Predicted ATPase of the PP-loop superfamily implicated in cell cycle control n=1 Tax=Methanopyrus kandleri RepID=Q8TXB8_METKA  E=0.0001 s/c=0.49 id=27% cov=29%
-------LSGGKDSVATLIDAADRWNVKVAVTVVHEFTDKTCLENARKAAEHVGV-DHEVVKLR-LREWFARAL-------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B7RI68(919-1025:2993) Non-ribosomal peptide synthetase, putative n=1 Tax=Roseobacter sp. GAI101 RepID=B7RI68_9RHOB  E=0.0001 s/c=0.46 id=28% cov=28%
------LLSGGKDSTYALYRTVALGHRPYVLTLDNGylsQDAKTNIKRAiRDLC-----VPHEFVTTSEMGTIFRESLS------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q0G0X3(38-202:458) PP-loop family protein n=1 Tax=Fulvimarina pelagi HTCC2506 RepID=Q0G0X3_9RHIZ  E=0.0001 s/c=0.30 id=33% cov=25%
-QRLLIAVSGGPDSLALLVLASRLPNLVFAVHaatVNHGLRREADMEAAhvAEVSQRLGV-PHE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q0W864(43-169:308) Predicted ATPase (PP-loop superfamily) n=6 Tax=Euryarchaeota RepID=Q0W864_UNCMA  E=0.0001 s/c=0.39 id=36% cov=24%
-----VAMSGGKDSAVTLSILVDTFttrsnIKFSAITVDEGiEGYRNEsIPYAKELCDRLGV-PHYVV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B9KYB4(328-431:586) Glutamine-dependent NAD(+) synthetase n=12 Tax=Bacteria RepID=B9KYB4_THERP  E=0.0001 s/c=0.47 id=37% cov=26%
FRTAVIGLSGGIDSSLTACIAADAlGPEnVTGLSMpsRYSSRHS--IEDAEELARNLGIRFLIV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q8TUL5(207-265:590) Predicted protein n=2 Tax=Methanosarcina RepID=Q8TUL5_METAC   E=0.0001 s/c=0.83 id=33% cov=23%
-KRLIVPLSGGLDSRIIVGMLKRLGvNDVICMS--YGRKGSRESEISRHVAETLG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_UPI00003840B6(224-312:587) COG0367: Asparagine synthase (glutamine-hydrolyzing) n=1 Tax=Magnetospirillum magnetotacticum MS-1 RepID=UPI00003840B6  E=0.0001 s/c=0.55 id=24% cov=24%
-----VFLSGGVDSSLVVAMMArfREGRDIHAFSIGFHEKAFDESGYAESVARAWGV-DHHV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A3DLJ8(36-156:310) PP-loop domain protein n=1 Tax=Staphylothermus marinus F1 RepID=A3DLJ8_STAMF  E=0.0001 s/c=0.40 id=18% cov=29%
--RVLLGLSGGKDSVVLAYILSKLretiGFKLYLTHLNLgiGEYSKKTVEIVRKISEKINA-PLIILDLREILSIG-----------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q72KY3(205-321:575) Asparagine synthetase n=1 Tax=Thermus thermophilus HB27 RepID=Q72KY3_THET2  E=0.0002 s/c=0.41 id=35% cov=22%
----VIPLSGGWDSRTIALALKKVGYEPL-IAFSYGKPKNAEAEVSRDVASQLGI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A3TZ17(23-172:414) PP-loop family protein n=2 Tax=Rhodobacteraceae RepID=A3TZ17_9RHOB   E=0.0002 s/c=0.32 id=38% cov=24%
-----VAVSGGSDSLALLHLLHDwasgSGLALHAVTVDHGLRAdsAAEAACVGEIAGRLGV-PHTV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C6A3M7(59-182:331) ATPase, PP-loop superfamily n=2 Tax=Euryarchaeota RepID=C6A3M7_THESM  E=0.0002 s/c=0.39 id=36% cov=25%
--RIAVGVSGGKDSVVLLHILHKLSqkfpFEIIAITIDEGiEGYRPEsVEIAKRNAKKLGIE-HKI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q46FA4(5-159:205) Conserved hypothetical ATP-binding protein n=4 Tax=Methanosarcinaceae RepID=Q46FA4_METBF  E=0.0002 s/c=0.31 id=35% cov=25%
-----VLFSGGKDSS-LSALLMEPFFEIELVTCSFGLLPNGEL--AAKTAKKLGF-PHRVLSLEW----------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B1NME1(11-125:327) Putative ArgG n=1 Tax=uncultured Acidobacteria bacterium cosmid p2H8 RepID=B1NME1_9BACT  E=0.0004 s/c=0.41 id=36% cov=26%
-ERIVLAHAGGLDTAVTIPWLAETYRaEIIAVTVDLGQK--KEwLEEARDRALATGAVRAHVVDV------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A1HRS0(21-172:468) TRNA(Ile)-lysidine synthetase n=1 Tax=Thermosinus carboxydivorans Nor1 RepID=A1HRS0_9FIRM  E=0.0004 s/c=0.31 id=26% cov=23%
--RVVVACSGGPDSLALVHLLHRlqpaYGFDMVVAHVDHmlrGAESAREAEFVRAFCRRLG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A1HQ96(21-166:277) ExsB family protein n=2 Tax=Thermosinus carboxydivorans Nor1 RepID=A1HQ96_9FIRM  E=0.0008 s/c=0.32 id=26% cov=62%
---AVIGFSGGTDSAFLAAAAYRvLGERAVAVTCYSATLPESERMEAAITARQIGIR---------HVLLPQNELDSDDFVRNDADRCYHCKK-----GR----FSALAAWAAAHGYHWVLEGANADDVG---DYRPG-LRALSELA--------VVRSPLleVGLTKAEIRELSRQWG-------------------------------------------------------
>UniRef50_B8E544(13-238:240) 7-cyano-7-deazaguanine synthase n=198 Tax=Bacteria RepID=QUEC_SHEB2   E=4e-61 s/c=1.04 id=69% cov=97%
--KAVVVFSGGQDSTTCLIQALTQYDEVHGITFDYGQRHREEIEVAKSLAKRLKITSHKVMDVTLLNELAISALTRDAIPV-SHELMENGLPNTFVPGRNILFLTLAGIYAYQLGAEAIITGVCETDFSGYPDCRNDFVKAMESALVQGMDKQLKIITPLMWLNKAQTWALADKYQQLDLVRHHTLTCYNGVIGDGCGDCPACHLRKRGLDEYMQDKTAVMASLDA-----
>UniRef50_B2KDX5(269-479:484) ExsB protein n=1 Tax=Elusimicrobium minutum Pei191 RepID=B2KDX5_ELUMP  E=5e-60 s/c=1.10 id=40% cov=90%
-KKAVVLFSGGLDSTVCLYWALKEGYECYALSVAYGQKHLKEIEVAQRLAKQAGVTHKHIEINLPWLAEATSLVGGAEIPATPMEQIGKSIPSTYVPARNLIFVSLGASWADSIGAEAVVLGPNAVDYSGYPDCTPQFYKPLSEAVRVGTrlGKKFEILTPIIKLNKAEIVKLGRK---LGAPLEQTWTCYNGGE-KPCGVCESCKLRRKGFE--------------------
>UniRef50_A8EWF5(7-228:228) 7-cyano-7-deazaguanine synthase n=27 Tax=Epsilonproteobacteria RepID=QUEC_ARCB4  E=1e-58 s/c=1.03 id=34% cov=95%
-KKAICILSGGMDSTLSSYIAKKDGFEIIAVHFNYGQRTQnRELKAFRDICNELDIKSKYEIDIPFFTQIGANALTDMSIDVPTGGLEA-GVPITYVPFRNGIFLAITAAIAEKEGATAMYIGVVQEDSSGYPDCTEEFIQDMKKAINQGTkeDTKIEIITPLVHLSKAQIVQEAIK---LNVPLELTWSCYK-EEEEACGVCDSCRLRLNGFEQAGKKDPIKYKEFQ------
>UniRef50_A7HHA2(7-231:233) 7-cyano-7-deazaguanine synthase n=6 Tax=Bacteria RepID=QUEC_ANADF   E=3e-54 s/c=0.95 id=41% cov=94%
-KRAVVLLSGGLDSTTCLAVARRDGFEAHCLSVDYGQRHKGELARARRLSRALGAADHRVVKVD-LSAFGGSALTDRAIAVPKGRSGRRRaaeIPVTYVPARNTVLLALALAHAETLGAEDVYVGVNAIDYSGYPDCRPAFLRAFERLATVATkagveGRPLRIHAPLLRLTKAGIVRLG---TSLGVPYRVTLSCYDPVRGRACGACDACVLRRKGFAEAGIPDPTLY----------
>UniRef50_Q3AR02(2-219:228) 7-cyano-7-deazaguanine synthase n=12 Tax=Bacteria RepID=QUEC_CHLCH   E=3e-53 s/c=0.96 id=32% cov=92%
--KAILLLSGGMDSLVTTAIAQQAGFELAAMHVNYGQRTmQRELNSFRAICSHYSIQQRLEINADFLGKIGGSSLTDLSMPVSVANLESHAIPASYVPFRNAGFLSMAVSWAEVIGAERIFIGAVEEDSSGYPDCRKIFYEAFNRVIELGTkpETHIEVVTPLIALKKWEIVRKGI---ELHAPFAFSWSCYKN-EGQACGVCDSCALRLRAFEQAGMEDP-------------
>UniRef50_UPI0001AF28A8(1-220:223) succinoglycan biosynthesis regulator n=2 Tax=Streptomyces filamentosus RepID=UPI0001AF28A8  E=1e-51 s/c=0.93 id=34% cov=94%
MARVIAIVSGGLDSVVLAHHLHAEGHEVHLLSIDYGQRHRKEHDYARIAADRIGAEHEIVDLSNVASMLPGYSLTDSQVDVPDQHYTAPGSVNV-VPNRNVILLSVAYGKAAAVKADQVAIGALAGDASTAPDCSAEFISSFNAMEKIACAGyapaHLEVVAPFIDLHKHDVIRLGEK---LGVDWTETWSCFKGTEV-HCGTCAACVDRIQAFERAETTDTTVY----------
>UniRef50_Q7NCE2(1-223:234) 7-cyano-7-deazaguanine synthase n=2 Tax=Bacteria RepID=QUEC_GLOVI   E=2e-50 s/c=0.90 id=44% cov=94%
MKKALVVFSGGQDSTTCAALACREYDEVHAVTFEYNQRHAIELESARAVGQALGLTGHEfIRLGPLLKGTSPLVSDAPLGQYASAAELPAGVEPTFVPGRNILFLTLAANRAFCLGTGDIVIGVCEADFAGYWDCRQVFVEAMARALGEGIYGDanaIRIHTPLMRLTKAETVKLSVEVlgERFEEVLALSHTCYAGVRG-GCGRCHACILRDRGFREAGVPDP-------------
>UniRef50_B0TFM0(6-246:247) Exsb protein, putative n=1 Tax=Heliobacterium modesticaldum Ice1 RepID=B0TFM0_HELMI  E=9e-48 s/c=0.80 id=38% cov=94%
-ERAVVILSGGLDSTTCMALADCRGEDIFALTFAYNQRHIREIEAAQAVACHYGA-HHQIIDLGAVFAASALTSTEIRPEVAaplggsavakmeamgcaekNPVAIATAIPATYVPARNILFLAYALSFAEKVGARRIYTGVNALDNPGYPDCRPEFIAAFQRMIDVGTkagteGRSVEVFTPLIEMNKADIIRLALD---LDAPLHLTLTCYYGERP-ACGECNSCRLRLEGFRLLGKGDPIAYRK--------
>UniRef50_C6XGK1(11-237:240) ExsB protein n=9 Tax=Bacteria RepID=C6XGK1_LIBAP   E=1e-43 s/c=0.78 id=44% cov=90%
---ALLLFSGGQDSSTCLSWALDRFDRVETLSFDYGQRNKVELEcrlCVRKKIVELmpkwkdSLGEDHILPLAILGDISHSSLTKNVAM----KIQDNNLPNTFVPGRNIIFLVFAATLAYRLGITNIVIGVCETDYSGYPDCRHDTIRAIETAINLGMESHVTVHTPLMWLKKYETWKLAQDIGgqdLVNLILEESHTCYLGKRdkryewGYGCNSCPACYLRQKGWMEFK-----------------
>UniRef50_D1R584(5-223:231) Putative uncharacterized protein n=1 Tax=Parachlamydia acanthamoebae str. Hall's coccus RepID=D1R584_9CHLA  E=2e-43 s/c=0.81 id=35% cov=93%
-KKAVVIHSGGMDSSICLALAIRTFsvENVLSLSFIYDQRHSSELEQAKKICQSWNV-DHIILSIPCLKEITTNALTDTSLPIQCGNGEA---PNTLVVGRNGLMAQLGAIHAHELGAHCIYMGIIGveGNHSGYRDCSRAYMDLKQTlLRLDLDDHLFTIETPLVDMSKKKTLELAQEMGVLEFLLNETITCYEGLEKLGCQKCPACILRNEGIRQFSAENPS------------
>UniRef50_Q2IUE0(4-208:210) 7-cyano-7-deazaguanine synthase 2 n=1 Tax=Rhodopseudomonas palustris HaA2 RepID=QUEC2_RHOP2  E=6e-42 s/c=0.84 id=34% cov=87%
-KKVLVLHSGGMDSTTCLLQAKAEGHDVASLGIDYGQRLLVEMMFAEGQCEKYSIPRH-VINVNWQKAERQIPLN------RSVEEMAHSVSPAFLPGRNIVFLGLGHAHAAGIGADELQIGLNCVDFSGYPDCTTQFYDSYCTMLNIGNPGGPKLVAPLLKMSKPEIARLA---STLGLQRNDTWSCYRPqireGSIVACGECDACKLHEFAWQE-------------------
>UniRef50_A4J5C7(3-218:228) 7-cyano-7-deazaguanine synthase n=4 Tax=Clostridia RepID=QUEC_DESRM   E=3e-37 s/c=0.73 id=26% cov=89%
---SVVLLSGGLDSAVNLAFARTEGNVKLALTINYRQRAAHKEIAAAAQLARYYAIPHRVIELPWLAEITKTALVRSESQLPEPKTEEldqlelagKTAAEVWVPNRNGLFVNIAACFAETLHCEIVVAGFNCEEAATFPDNTPEFALAASAAMQYSTANQVKVLSYTGRLNKKDIVALGQ---RLQLPWELIWSCYRG-EALMCGKCESCQRMIRAFH--------------------
>UniRef50_B8GP80(12-211:213) ExsB family protein n=1 Tax=Thioalkalivibrio sp. HL-EbGR7 RepID=B8GP80_THISH  E=1e-36 s/c=0.78 id=26% cov=86%
---SLLLLSGGIESATLLA-LESRQRPVTPLVVDYGQRGAlRERDAARAQCESHGLTPVELDLSATGGTFRDGLL---------------KRPHVPLPHRNLVILSLAVSYAARGGIDRVVLALNRDDLAAYPSASPGFLEHF-RALIHDLQPGLEITTPLIDRDKAGVIRLGVS---LGVDFARTWSCLLGYE-THCGACPQCLHRRAAFRAAGIADPTRY----------
>UniRef50_Q24ZT5(5-205:220) 7-cyano-7-deazaguanine synthase 1 n=1 Tax=Desulfitobacterium hafniense Y51 RepID=QUEC1_DESHY  E=3e-36 s/c=0.77 id=22% cov=87%
--KVVLLFSGGIDSTVLLFWLLSRNYEIFPLFINYGQKsYEGELEAINKILKDLNTKNNLLTLNMPELQLVGSGALVGEYP-KNISSHNEWYASEFFPNRNMILLSIAATYGYKLQISKIAIGVVGD---SYQDTTRTFLEAMEMTLAQSIA-RYELIAPFAGHPRQKVIEEAY---RLQVPLKSTFSC-NAMGNRHCLLCTSCYEREKAI---------------------
>UniRef50_B7GTM4(7-228:251) ExsB family protein n=2 Tax=Actinobacteridae RepID=B7GTM4_BIFLI   E=2e-35 s/c=0.68 id=22% cov=93%
--RVALLLSGGPDSTTLLYDLLNQGKEIYAVTFNFGETEGcNESQHAQRIVTNLHSERLHHYQYDFseqFKRFYELPQPQFLRKAFGPFVVAPNKEEHVQPFGSAIALMLMASWALKHDIVDVYYAVHSND-AVFHDNHASYFEALHTVTVecEGDEYGVTFHTPYLSINKCAVIQKG---MGLGVPFGDTWSCALGGTV-HCGVCDPCRDRRTSFEILGIKDPVLY----------
>UniRef50_A9U3Q1(6-211:290) Predicted protein n=1 Tax=Physcomitrella patens subsp. patens RepID=A9U3Q1_PHYPA  E=3e-34 s/c=0.71 id=25% cov=86%
---SVVLMSGGIESAVLLYNWRSSSALLHPLYINYGQRgAAMEERASDKICNNLGLELSRIDMSAVGNKFRELQHGAKS--------------FVPLPHRNLVILGLAASYASQVGSSKVALGLNKDDLGSYSSASQNFMDSF-RSTAASLEPPVTLIAPLSHFTKAEVIRLGK---RLGVPFADTYSCMVG-RPVHCGRCHQCRSRQLAFASASEQEPA------------
>UniRef50_Q13AQ3(3-204:206) ExsB n=6 Tax=Proteobacteria RepID=Q13AQ3_RHOPS   E=3e-33 s/c=0.71 id=24% cov=87%
---ALLLCSGGLDSTTVGYWLVEKNISFQPLFFDYGQHCvEKEWETLQEVLPISGlVSPLLRINISEIFQHSPSRL----IAEPNLWTEHVEDDDLYIPYRTLMFFSVGACIAQTRGLDAVYAGFINSNHAKELDCSAAFLNNLDSLSR--SLGPVRFELPFRDWSKADVVRRA---NELRVPVGKTYSC-QLFSDTPCGACPNCVERISAIESF------------------
>UniRef50_C9Q119(153-381:432) Putative uncharacterized protein n=1 Tax=Prevotella sp. oral taxon 472 str. F0295 RepID=C9Q119_9BACT  E=7e-31 s/c=0.59 id=21% cov=85%
-----CMLSGGLDSFIGAINLLKDGKEPIFVS-HYG-----------------GGKGVKVYQDSVVNSLKIQYAVDSKRFFRFYAASQNGAEDT-TRSRSLMFFAHAIVLASGIGHHvDLYVPENGVISLNIPltvmrlgslstrTTHPYFMGMFQKLL-TGLDIDISLVNPFQMQTKGEMMKTCKDLDFLNAHYQDTLSCSHPDQGRwtgdavgHCGECLPCTIRKAAIKAAGLEDVTTY----------
>UniRef50_C6ALB1(147-366:438) Putative uncharacterized protein n=2 Tax=Proteobacteria RepID=C6ALB1_AGGAN  E=6e-28 s/c=0.57 id=19% cov=84%
-KDCVCLFSGGLDSAIGTIDLLEQGHSPVLVSHSY----KGDKSRQQAIIQQLNQNG-YINQFSQFNAIAQPHLNNGKSTEITMRT------------RSLNFLAFAIVSAYALQKVAqkkidILVPENGVISINapltvrrvgtlsTRTTHPYFIQEIQKLF-TAVNIPFTLRNPYQFKTKGQMIAECRNLPLLQQIIPDTVSCSHWKRkNQQCGVCVPCLIRRASLH--------------------
>UniRef50_A9GG06(117-351:435) Putative uncharacterized protein n=1 Tax=Sorangium cellulosum 'So ce 56' RepID=A9GG06_SORC5  E=5e-27 s/c=0.52 id=19% cov=92%
---AVCLFSGGVDSLIGAINLLEsdRKSRVVLVgHYDSTHTPGTQKVLADELIQEYGDER----VLPLRVLVRPAPIRDGVQAYPLPAVKESTTRS-----RSLVFLGLGMAVAAALGpAVPLYIPENGFIAINVPlhgsrvgscstrTTHPYFLDRIANALGV-VGVKNPIVNPYVYKTKGEMVRECKNQDLLRRVAHITVSCAHPERKQnetntwpNCGYCYPCLIRRAAFNWAGFESSSMYARYR------
>UniRef50_Q5WAJ2(145-373:430) Putative uncharacterized protein n=4 Tax=Bacillus RepID=Q5WAJ2_BACSK  E=6e-27 s/c=0.54 id=16% cov=87%
--KKVCMFSGGLDSFIGAIELLDDTSENDTLFVS-----------------HYGGGKGIKEYQDILREELISKYQLTESNFYSFYASAKNGVEDTTRTRSFMFFSHAVVLASSVDrpvnlvipengliSLNIPLTNSRLGSSSTRTTHPFYLSLFQKLLD-NLKIMVKILNPYQFKTKGEMIRECSSIEFLQKNITNTMSCSHPDWGRwagesevcHCGYCLPCVIRRSAIKNAGIQDETIY----------
>UniRef50_B1ZBL1(3-193:214) ExsB family protein n=4 Tax=Proteobacteria RepID=B1ZBL1_METPB   E=1e-25 s/c=0.62 id=27% cov=82%
----VLLFSGGLDSTALAWWQRPD----ACLFVDYGQRPaAGERAAATSIAAEFGLR---------LETLQVDLSGLGLGPLAGGEPAALARAPEWWPYRNQILVTLAGMRFVAEGLSEILIGTVATDV--HADGRAPFLRTLDRLMRL-QEGGVRVVAPARHLSGPALLA---ASGLPASALGATFSCH--VMEYACGQCRGCEKHRETLRSF------------------
>UniRef50_Q4UTY2(141-356:428) Putative uncharacterized protein n=2 Tax=Gammaproteobacteria RepID=Q4UTY2_XANC8  E=3e-25 s/c=0.54 id=18% cov=85%
-EDSVCLLSGGMDSLIGAIDLAESGRRSIAVSNTVPGD---------------GHNQHSFAEAVGFKHLPLNH---------NASPPSDGSREPSQRARSIIFLAFGVLAATSLQAYQdgaqvplfiCENGFIALNPPltgtrlgslSTRTAHPEFLHGVQSVLDAA-GLRVNLINPYQHKTKGEMSRECADQDLLRNLAASSVSCgrYRRYGYNQCGRCIPCQIRRSAYLAWGQPDPTDY----------
>UniRef50_Q5JCY1(182-340:381) Probable tRNA sulfurtransferase n=14 Tax=Thermococcaceae RepID=THII_PYRKO  E=3e-24 s/c=0.71 id=19% cov=69%
--KVVALLSGGIDSPVAAFLMMKRGVEVIPVHIYMG---EKTLEKVRKIWNQL--KKYHYGGKAELIVVKPQNREEMLKKIKELGKE----KYTCVLC-KFMMVKHADRIAKEFGAKGIVMGDSLGQVAS---------QTLENMYIVSQASDLPIYRPLIGLDKEEIVDIAKKIGTFEL---------------------------------------------------
>UniRef50_Q72HP1(176-331:406) Probable tRNA sulfurtransferase n=3 Tax=Thermus RepID=THII_THET2   E=6e-24 s/c=0.72 id=25% cov=67%
--RVVALLSGGIDSPVAAYRLMRRGAEVVLVHFHpFPLLSGASREKAKALAERLARFQHRLRL----------HLVPFSEVQRHIIVEAPTAYRVVLYRRY--MLRIAEAIAREEGALALCTGDSLGQVAS---------QTLENLHAVNQAATLPVFRPLIGWDKEEIVAEAQRIG-------------------------------------------------------
>UniRef50_C6MK22(157-376:700) Putative uncharacterized protein n=2 Tax=Deltaproteobacteria RepID=C6MK22_9DELT  E=6e-23 s/c=0.50 id=24% cov=83%
----VVMFSGGLDSLAGAIDeVLNEKHRVVLVTHkSTPKLNKRHRRLEKMIADKAGenAPLHIGVRVNKNKGLNYEYTQRS---------------------RSFLYVSIGATIAKMINLKSVRFYENGVISLNLPVCaqvvggratrttHPRVIRGFQEIISLVAGEPFTIENPYIWKTKADVVGVITKAGCQEMIAAST-TCTHTWEmtnhHTHCGTCSQCIDRRFAVIAAKAD---------------
>UniRef50_A6D100(47-288:372) Putative uncharacterized protein n=1 Tax=Vibrio shilonii AK1 RepID=A6D100_9VIBR  E=3e-22 s/c=0.44 id=21% cov=75%
--KAVSLLSGGLDSFIGAIDLLNSDIDTLFVGHyakDGTQHYQNQVEQA--------LKGHY---PDYFKGYVKGCLIFDKSVFKGGNQEIDSENSQ--RSRSFMFLSMAAYLASSMGelCKLIVpeNGFIALNVPLDPLRiganstktvHPNFMSKMGEIFDF-LGLNIGLINPYRHMTKGEMMANCKNKSLLTKHAHETLSC-------------------------------------------
>UniRef50_A9CLS9(142-366:444) Putative uncharacterized protein n=1 Tax=Agrobacterium tumefaciens str. C58 RepID=A9CLS9_AGRT5  E=3e-21 s/c=0.46 id=19% cov=88%
----VALLSGGLDSLIGAIDMEADGLE-KPVYVSN--RVRGDVAKQEKFASRLGA--------------GNRLLSLNADPRTSGATAEISQRPRSIVF--IAFAALAVTLLDRYNDGEVVDLHTPENgfislniplttlrrgSLSTRTTHPKFIEMLQGLFD-SLELRIRLRNHHQLKTKGTMMLGSKNQELLIELASESMSCGRAGRiYTHCGRCLPCLVRRSSFLKWagrLDADKTVYVHPKAE----
>UniRef50_Q2FLN6(172-339:387) Thiamine biosynthesis protein n=1 Tax=Methanospirillum hungatei JF-1 RepID=Q2FLN6_METHJ  E=4e-21 s/c=0.61 id=22% cov=68%
--KAVALISAGIDSPVAAWLMMRRGVRMIFLHIEPGKFGGEDIR--RNLENNLAALSHWVPGLELPV-----ITIPAEPFYQALMTLSEPKLRCVLCKRG--MLELASRYAQKSGCDGIITGDNLGQVAT---------QTLHNLAPISAGIEIPIYRPLIGYDKEEIITLARKIG-------------------------------------------------------
>UniRef50_B2IBH3(31-222:431) tRNA-specific 2-thiouridylase mnmA n=141 Tax=root RepID=MNMA_BEII9   E=9e-21 s/c=0.53 id=21% cov=70%
--RVVVAMSGGVDSSVVAALLKREGYEVIGVTLqlyDHGEavhrkgacCAGQDIQDARQVADQLGIPHYVLDYEERFRRkvidPFAQSYATGETPIPCVSCNSE------------IKFADLFETAQHLGADVLATG-HYVSSKAEADGGRALYRSLDSSRDQSyflfatTNAQLELLRfPLGDLAKPDVRQMARQLG-------------------------------------------------------
>UniRef50_UPI0001B54B61(118-322:423) PP-loop superfamily ATPase-like protein n=1 Tax=Streptomyces sp. AA4 RepID=UPI0001B54B61  E=2e-20 s/c=0.49 id=23% cov=81%
-----VLFSGGLDSSAGLALRL-GGPPLLPVSV----RTNNDMAGVQeRVLSRLRGVSREVLPAASFRV----NLTESRTRAPGAKQENSQR------SRGLLFLAAGIAVAITLGKGRLWFLENGIGAINlpylrsqvgsqaTRSAHPRTVQAMARLAGTLTGQDFAVETPLLGLTKAE--AVSAVPPEYEHAIACSVSCDTGFASRisghpPCGTCTSCLLRRQA----------------------
>UniRef50_A3DEB6(181-345:392) Probable tRNA sulfurtransferase n=34 Tax=Bacteria RepID=THII_CLOTH   E=3e-20 s/c=0.61 id=20% cov=70%
--KAVLLLSGGIDSPVAGWMIAKRGVEIEAVHFySYPYTSERAKEKVIELTKILATYCQKI-----------NLHIVPFTEIQLEINEKCPHEELTIIMRRAMM-RIAEIIANKTGALALVTGESVGQVAS---------QTIQSLVVTNAVVSLPVFRPLIGMDKNEVVDIAKKIGTFEtsiLPYED-----------------------------------------------
>UniRef50_C5PNW4(8-187:198) ExsB superfamily protein n=1 Tax=Sphingobacterium spiritivorum ATCC 33861 RepID=C5PNW4_9SPHI  E=4e-20 s/c=0.56 id=23% cov=78%
-----LLLSGGVDSICLAYGLKPD----IAYTINYGQiPASREIYVSRYICNLLRI-QHKVIEVNCKSLGSGILINEERLDI--------SPSQEWWPYRNQLLITLAAMQAIKDKIGVLHLASVKSD-SFHKDGTPQFYDLINELVKY-QEGNISIVCESTGYYSHELVKKYNVPLE---IIAFAHSCH--ISNTACGQCPGCK---------------------------
>UniRef50_B1L665(176-338:373) Thiamine biosynthesis/tRNA modification protein ThiI n=1 Tax=Candidatus Korarchaeum cryptofilum OPF8 RepID=B1L665_KORCO  E=5e-20 s/c=0.61 id=18% cov=71%
--KVLALISGGIDSPVAAWLLMRRGAQIIPLHFR---KSSAEEETFIKIVNVLRRYSYGVKMEPMILEHGEFLS----------EISREAREWTCLLCKRRMLLT-ANRIAKEIGAHGIVTGDSLGQVAS---------QTLANLEVESRCLEKPVFRPLIGMDKEDIVKIAKEIGTYDISISYKESC-------------------------------------------
>UniRef50_C6D5K7(179-344:406) Thiamine biosynthesis/tRNA modification protein ThiI n=2 Tax=Paenibacillus RepID=C6D5K7_PAESJ  E=9e-20 s/c=0.60 id=20% cov=71%
--KAMLLLSGGIDSPVAGWMAMRKGLELEAVHFHsYPFTSDKAKEKVIDLARRL----------SYYAGAPLKLHLVPFTDIQTRLVQAKQDSMMITLMRRA-MLRITEQLADRNGAGGIVTGESLGQVAS---------QTLSSMNVIGRATVLPLLKPLIMMDKQEIINEAVRIGTFEtsiLPYED-----------------------------------------------
>UniRef50_C5CE34(177-337:404) Thiamine biosynthesis/tRNA modification protein ThiI n=1 Tax=Kosmotoga olearia TBF 19.5.1 RepID=C5CE34_KOSOT  E=2e-19 s/c=0.61 id=23% cov=65%
---ALLLLSGGIDSPVAGWYALKRGITLHAIHFASPPYTgekafEKVLDLAKALTKYNGGRDMLLYRVHF-----------TKLQLAIHRNVRESLS--LVIQRRAMM-RIATKIAKEHGYKAIVTGENLGQVAS---------QTIENLHTIGSATDILVLRPLTGFDKIETIQIAKK---------------------------------------------------------
>UniRef50_C6J374(180-339:410) Thiamine biosynthesis/tRNA modification protein ThiI n=2 Tax=Bacillales RepID=C6J374_9BACL  E=2e-19 s/c=0.61 id=26% cov=67%
--KAMLLLSGGIDSPVAGWSALRRGLEIECVHFHsYPFTSKkaeqKVIDLANVLAQYSGFIKLHLVPFTEIQT----------------KLAQTGQDNLIITMMRRAMLRIATKLAERNGALALVTGDSLGQVAS---------QTLSSMNAIGRVTNLPILRPLVMTDKVDIIAMAQQIGTYDL---------------------------------------------------
>UniRef50_D2B6F2(190-347:400) Thiamine biosynthesis protein ThiI n=2 Tax=Streptosporangineae RepID=D2B6F2_STRRD  E=2e-19 s/c=0.62 id=25% cov=68%
--RGLVLMSGGIDSPVAAYRMMRRGLRVDFLHFSgIPFTTSESIYKAYALVRALD------------RFQGRSRLWVVPFGKAQQSIKASGQDRLAVISQRRLMLKTAEEVARRLRAGALITGDSLGQVSS---------QTLQNITAQDDAVDLPILRPLIGLDKTEIMAEARRIGTLE----------------------------------------------------
>UniRef50_D2MP56(177-341:472) Thiamine biosynthesis/tRNA modification protein ThiI n=1 Tax=Bulleidia extructa W1219 RepID=D2MP56_9FIRM  E=3e-19 s/c=0.59 id=22% cov=68%
--KVMMLLSGGIDSPVATYQLIKRGLKVEAVHFAappYTSEAAKNkvLKLASMISDYQGGMKVHVVPFTELQL--------------DIYRVAKDPYAITLMRR--MMFRIAEKLAINNRCLAIGTGESLGQVAS---------QTLESMVTINDVVHIPVLRPLVSMDKVEIIQLAREIGTYEtsiLPYED-----------------------------------------------
>UniRef50_B7H703(180-339:404) Probable tRNA sulfurtransferase n=75 Tax=Bacteria RepID=THII_BACC4   E=2e-18 s/c=0.59 id=21% cov=65%
--KVMVLLSGGIDSPVAAYLTMKRGVSVEAVHFHSPPFTSerakqKVIDLAQELTKYCkRVTLHLVPFTEVQKTINKEIPSSYSMTVMRRMMMR-----------------ITERIAEERNALAITTGESLGQVAS---------QTLDSMHTINEVTNYPVIRPLITMDKLEIIKIAEEIG-------------------------------------------------------
>UniRef50_Q73PV6(2-203:366) tRNA-specific 2-thiouridylase mnmA n=2 Tax=Treponema RepID=MNMA_TREDE  E=2e-18 s/c=0.47 id=31% cov=26%
--KVLVGLSGGVDSAVAAKLLIDQGYDVTGVTMQLLPKLSGiykeqtdDIEDAKKVADKLGIK-HIVYDM------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A1STI9(8-206:367) tRNA-specific 2-thiouridylase mnmA n=4 Tax=Proteobacteria RepID=MNMA_PSYIN  E=2e-18 s/c=0.48 id=24% cov=26%
--KVIVGMSGGVDSSVSAYLLQQQGYLVEGLFMKNWEEddtdqycaAAQDLEDAQSVCDKLGIPLHTI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_UPI00017F5D79(157-385:487) hypothetical protein CdifA_02378 n=1 Tax=Clostridium difficile ATCC 43255 RepID=UPI00017F5D79  E=4e-18 s/c=0.41 id=20% cov=88%
----VSLFSGGLDSFCGALRLLENNKKVFFVTC-------MEHKLLKKRVND--IYRRVDRGYPKLNKNIYVFSANPKRPMNVSKELLNKFSEDTSRSRSFLFMAVAIAVVSIINPKEgVYIPENGFIGinlpltkSRLGSCSTRTthvwaLKRLNEILTL-LDINIPITNFYKYNTKGEIVDEFKNNKIFKECVKLTLSCSHPTHGRmagatppiNCGYCYPCMIRRASLYKIGFDD--------------
>UniRef50_A7GTS8(180-339:403) Probable tRNA sulfurtransferase n=5 Tax=Firmicutes RepID=THII_BACCN   E=4e-18 s/c=0.58 id=19% cov=67%
--KVMVLLSGGIDSPVAAYLTMKRGVSVEAVHFHSpPFTSERAKQKVIDLAQEL---TKYCKRVTLHLVPFTEVQKTINKEIPSSYTMTVMRRMMMRIT---------ERIAEERNALAITTGESLGQVAS---------QTLDSMHTINEVTNYPVLRPLITMDKLEIIKIANEIG-------------------------------------------------------
>UniRef50_C0E8G4(1-182:352) Putative uncharacterized protein n=1 Tax=Clostridium methylpentosum DSM 5476 RepID=C0E8G4_9CLOT  E=5e-18 s/c=0.51 id=21% cov=70%
--------SGGVDSSVAAALLIEQGYEVVGATFRLWKPEDdlfdseatccslDDINDAREVCHQLGIPHYVLNLKREFKEAVVQNFVE--------EYQAGRTPNPCIVCNQKIKFDYFYQKAAALGFDYVATGHYArieqNEQGEFQLKTAAYAQKDQSYFLYGIPYPNlgHILFPLGGYTKPQVRELAEKYG-------------------------------------------------------
>UniRef50_D0WEQ1(184-341:421) Thiamine biosynthesis/tRNA modification protein ThiI n=1 Tax=Slackia exigua ATCC 700122 RepID=D0WEQ1_9ACTN  E=6e-18 s/c=0.59 id=21% cov=69%
--KVVCLLSSGIDSPVALWRMARRGATCVAVHFSGRPQTQATSEF---------IVDDIAHTIEGFGGIARMYVVPFGDYQRTIAGTVPQRLRIIVYRR--LMMRVAAAIARREGAKALVTGESLGQVAS---------QTLDNLAATGSAVDMQVFRPLIGSDKLEIIADAQKLGTFDL---------------------------------------------------
>UniRef50_A6KZV1(6-187:375) tRNA-specific 2-thiouridylase mnmA 3 n=23 Tax=Bacteroides RepID=MNMA3_BACV8  E=1e-17 s/c=0.51 id=38% cov=25%
-KRVLVGMSGGIDSSATCIMLQEQGYEVVGVTMRTwdvpsrfstpGQDEPDDVLEARALAERLGIEHH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B5DNY9(2-211:387) GA22395 n=14 Tax=Neoptera RepID=B5DNY9_DROPS   E=2e-17 s/c=0.44 id=22% cov=81%
IRNIVVGMSGGVDSAVSAHLLRERGHRVMGVFMRNWDEHdeagrcsgEQDLKDAEWACQRLGIELRQVNYVKEYWTAVFSAFLDDYQQGLTPNPD-------ILCNRHIKF-DLFHRHAlDKLGYDAVATGhyarnslgnflEHRADGGEARLLIPADTFKDQTFFLAGIPRQAlqRTMFPLGDLAKNEVKLLARRIGlqRLAHKRESTGICFVGKRD-------------------------------------
>UniRef50_A3DLP8(168-320:375) Thiamine biosynthesis protein n=1 Tax=Staphylothermus marinus F1 RepID=A3DLP8_STAMF  E=2e-17 s/c=0.60 id=23% cov=45%
----VVLLSGGVDSSLAAWYAMKRGARIIPVFIDLGKYWSEQAR--RRFYEALSLVYEWVP--------------WDKIKTYIVRGAEKILESTNIPARlrcllcKANMYRIASIIADKEECLGIVTG-------------------------------------------------------------------------------------------------------------
>UniRef50_Q8ZT61(172-332:484) tRNA sulfurtransferase n=5 Tax=Thermoproteaceae RepID=THII_PYRAE   E=2e-17 s/c=0.57 id=18% cov=68%
--KVLALVSAGIDSPVAAWMLMRRGAHVDVLYCNLGGT--ITLRHALEVIKRL-----------LAWSYGYNARVIIADCGPVARAMRRGVREElWNIAFKRALYRIGVEIAKRLGAIALATGESLGQVSS---------QTLQALAAVEAGIDMPILRPLIGMDKDEIVKHAQKIGTYEL---------------------------------------------------
>UniRef50_C4DG87(146-357:420) Predicted PP-loop superfamily ATPase n=1 Tax=Stackebrandtia nassauensis DSM 44728 RepID=C4DG87_9ACTO  E=3e-17 s/c=0.43 id=22% cov=85%
---AVALFSGGLDSFCHAGLLRPA-SKVVLVSHGLGPNLR---ERKRELRAALGGET---VMSAEFQVRINAVPGTEREPHPRTRALLLLAAGVLVCAANGV----DTLHCPENGLLALHPAKAPL-WSQSATPIPPMTVHLANALLDSLDVDTRVVNPYAELTKGEVCERAVDAGWRRSLLGRTITCVNPDKKSsgrfgNCGYCRHCLVRHAAL---------------------
>UniRef50_B9QRC5(144-361:457) Putative uncharacterized protein n=1 Tax=Labrenzia alexandrii DFL-11 RepID=B9QRC5_9RHOB  E=7e-17 s/c=0.41 id=22% cov=76%
---AIMAFSDGMDSRAVAGL----------------------------IGSGLGPKLVRVRVgSNDIGRPDKKNRREPFTMVPYDVPCNMPNREASARSRGFKFALISGIAAYLSGASEIIIPESGqgaigpaiapvVHAYPDYRNHPRFTQRMERLLKALFGKEIRYVFPRLWNTKGETLRSFATLPE-GSNWHTTRSCWRsnrwcsvNGKRRQCGVCAACMLRR------------------------
>UniRef50_A7I2L9(2-182:368) tRNA-specific 2-thiouridylase mnmA n=19 Tax=Campylobacter RepID=MNMA_CAMHC  E=7e-17 s/c=0.50 id=20% cov=26%
--KILVALSGGVDSAVSAKILKDAGYEIEGCYMKLHGRddyHAKNIEKVQDVGNFLEIKTHIL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6DMI7(198-364:433) Putative uncharacterized protein n=1 Tax=Lentisphaera araneosa HTCC2155 RepID=A6DMI7_9BACT  E=1e-16 s/c=0.53 id=18% cov=69%
---VLCLLSGGIDSPVAAFKAMQRGSHVNSITF--ESFPYTQPELIDKVAK-------LQTILDKFQDHPAKFYACNMAESQKMIRDDCSERFRTILYRR-IMMRVSTVVAEHLKTKALLTGEAVGQVA---SQTLANMDTINRATNTL------VLRPLVCMDKNEVIAIAEKAGTFDV---------------------------------------------------
>UniRef50_A3CVZ1(17-160:257) ExsB family protein n=1 Tax=Methanoculleus marisnigri JR1 RepID=A3CVZ1_METMJ  E=1e-16 s/c=0.61 id=26% cov=62%
---VAVALSGGTDSSVLLALARHHGIQVIAISVDTGLTPPGELAAARKLSERLGL-PHVVIPLDML----------------DIPAVRENRPDRCYVCKRAMMEAIVAE-ARRQGCRTVVDGTHADD-------RPAARPGMRVLSELG------IKSPFAecGMGKADVEALARELG-------------------------------------------------------
>UniRef50_A0B7K6(129-288:335) Thiamine biosynthesis protein n=1 Tax=Methanosaeta thermophila PT RepID=A0B7K6_METTP  E=5e-16 s/c=0.54 id=18% cov=67%
--RMLALISGGIDSPVAAWLIMRRGCPVALLHLDV-SPYADSIEQVVRQAE--------VLQSWMSGRRLDLAIVRNARAIEMIS--SRYPRETCVLCRR-LMYHISTLVMKRLRAKGIVTGYSLGQVAS---------QTPENIMAEQVGIEAPVYHPLIAMDKTEIIELARRIG-------------------------------------------------------
>UniRef50_Q8D1V0(225-398:522) GMP synthase [glutamine-hydrolyzing] n=2 Tax=Bacteria RepID=GUAA_WIGBR  E=6e-16 s/c=0.50 id=20% cov=70%
-EKVILGLSGGIDSFTSAILIHKAiGNNLFCICIDNGLLRNDEILKIKNLIKKVGKINVIYINHKKRFLKSLNGITDPEKKRKTI---------------GNLFFKIFQEQADILKAKWLAQGTIYPDIIESSQNnllkKDNFIKSHHNVCPLPKGIKLKILEPLKHLFKDEVKKIAKKIG-------------------------------------------------------
>UniRef50_A4RU81(256-425:714) Predicted protein n=3 Tax=Ostreococcus RepID=A4RU81_OSTLU   E=7e-16 s/c=0.51 id=19% cov=71%
-----VSLSGGVDSMVLAYILKHQGYDVVTLHIDYKNRPESTEEA--DFVDDWSLRHGMKFERCTVDQIRRGV-------TPREQYEIESRRIRYG------FYKEAGA---KHGFPAVLLGHHHGDVQEniiTNLMRGANLLSVNGMSDEGVVEGVRIWRPMLSHVKDDVLTFAHAYGiPYFLDSTPTWS--------------------------------------------
>UniRef50_A2CB44(36-225:409) tRNA-specific 2-thiouridylase mnmA n=60 Tax=cellular organisms RepID=MNMA_PROM3  E=5e-15 s/c=0.44 id=21% cov=73%
--RVAVGLSGGVDSSLSAALLVEAGWQVEGLTLWLmsgkGACCSDGLIDAAGICEQLKIPHHVVDSRATFQAEIVDQLVQ-------GYQQGVTPLPCSRCNRSVKFAAMLSWAEKERQLHRVATGHyarirHREDpepqqaLPGDSSGRHQLLRGLDQnkdqsyfLYDLSQDVLAKVIFPLGELTKAETRQEAERYG-------------------------------------------------------
>UniRef50_A8X0Z8(1-243:393) Putative uncharacterized protein n=2 Tax=Caenorhabditis briggsae RepID=A8X0Z8_CAEBR  E=3e-14 s/c=0.33 id=21% cov=73%
MKvpRVVIGMSGGVDSAVSAFLLKQKGFDVVGLHMvtHSRQREsekknisqinwdsqeegsstcprSKDEADARNVCNRLNIPFHTVNFVKEYWNHVFLKFLENYKIGRTTVPDIDCNYS--------IKFDAFHKVAqETFDADFIATGHYATTSFGDFQQNRKHSEAIrlfsgrdplkDQTFFLCTVTQEQLKRamfPLGSLQKSEVKRIAEQQG-------------------------------------------------------
>UniRef50_C2BDE5(205-356:405) Thiamine biosynthesis protein n=1 Tax=Anaerococcus lactolyticus ATCC 51172 RepID=C2BDE5_9FIRM  E=5e-14 s/c=0.53 id=16% cov=64%
-----------IDSPVAGFMVAKRGMKIDCLHFHsYPFTSKRALQKAIDLAEIMSAY-----------TGKMRVYSVNLANIYKAINQNCERRETTILSRRFMM-RIANKISEANGYQALITGESLGQVAS---------QTIESVAVINDSSDLPILRPLIAMDKKDIIDISLKIGSYD----------------------------------------------------
>UniRef50_Q3Z8D8(8-223:357) tRNA-specific 2-thiouridylase mnmA n=5 Tax=Dehalococcoides RepID=MNMA_DEHE1  E=7e-14 s/c=0.37 id=21% cov=71%
----MVAMSGGVDSSVAAMLLLEQGYDVAGVSLQlksnnepYGNGYNlKLINRAREVAAALGIPHYVVDLSDIFSQRV---IADFCQQYSQGRTPNPCIRCNYYVKIGALLEKIpdfnAGYLATGHYARVLSDenGTHLLKGADEKKDQSYF------LYTLPPESLSRLIFPLGKRYKKDIIRLADKMK-------------------------------------------------------
>UniRef50_B1L455(16-158:260) ExsB family protein n=1 Tax=Candidatus Korarchaeum cryptofilum OPF8 RepID=B1L455_KORCO  E=1e-13 s/c=0.55 id=32% cov=28%
---VIIALSGGLDSSTLAALCKKlLGDKAIAVTVASELQPEEEIEGARRVAEEIGIR-HILIEVSLLKE-------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B8D0L5(192-348:396) Probable tRNA sulfurtransferase n=4 Tax=Clostridia RepID=THII_HALOH   E=2e-13 s/c=0.50 id=17% cov=63%
-----------IDSPVAGWLAMKRGIELEALYFHsFPYTSDRAKEKVIDLTKVLSRYCKKI-------KLYVGYFTDIQRAIQENCPQKY-----YITIMRRMMYRMAERIARKNGDLVLITGESVGQVAS---------QTLESMNVINEVTNMPVLRPLATMNKTEIMDLAREIG-------------------------------------------------------
>UniRef50_UPI0001AF1546(21-205:402) argininosuccinate synthase n=1 Tax=Streptomyces roseosporus NRRL 15998 RepID=UPI0001AF1546  E=4e-13 s/c=0.42 id=21% cov=80%
---VVTLFSGGLDSSYLLLRLRRMGmREVHAVSVDIGEDESSSYK--QQVAEELGATIHILDRREEFAERYVAPAIAAQAVYLGIHPVSSTLSRPLIAH-------SAVELARGLGAQAVLHTANR---------SQNTLRRLNGALRLLRYEGA-FGSPYdLDPVTRDDKLVELRAAGIDLLAGRIVS---GDSNLWC----------REFESGILDDP-------------
>UniRef50_A5VIU7(189-339:406) Probable tRNA sulfurtransferase n=43 Tax=Bacilli RepID=THII_LACRD   E=5e-13 s/c=0.51 id=15% cov=61%
-----------IDSPVAAYLGMKRGVSMEMVHFFSPPYTSPQaLAKAKQLTERL---AKYSGSIKFIQVPFAEIQETVKEKVPEGYLMTIQRR---------MMLRLAAALMIKRHGLAIFNGESLGQVAS---------QTMESMLAINDVTSYPVLRPVLSFDKTEIIKIAQ----------------------------------------------------------
>UniRef50_C3XLI4(552-719:852) GMP synthase n=1 Tax=Helicobacter winghamensis ATCC BAA-430 RepID=C3XLI4_9HELI  E=6e-13 s/c=0.46 id=18% cov=21%
FSKVLCAVSGGVDSSVVATLLYRAiGENLIPVFVDTGLLRKGEREAVEA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C1EG18(3-216:346) Predicted protein (Fragment) n=2 Tax=Micromonas RepID=C1EG18_9CHLO   E=8e-13 s/c=0.36 id=18% cov=79%
--RVAVGLSGGVDSAVTAWLLKSAGFDVTGVLMrnwDEAEETGGECSFEKDQRDARAAARAVGIPLTEVDFVKEYWHSVFEPFLRDFDGGGATPNPDLACNRHIKFGALLDHCLRSLGADLLATGHYARIVRIDETNPPRLLRGIdpdkDQSYFLASVRGESLERacfPLGGLTKREVRELA--AGPANLPAAVT----------------------------------------------
>UniRef50_Q8WSN4(230-424:720) GMP synthetase n=35 Tax=Fungi/Metazoa group RepID=Q8WSN4_DROME   E=2e-12 s/c=0.38 id=20% cov=23%
--KVLLLVSGGVDSSVCAALLRRALYphQIIAVHVDNGFMRKKESEKVERSLRDIGI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B8GHF0(48-218:304) PP-loop domain protein n=1 Tax=Methanosphaerula palustris E1-9c RepID=B8GHF0_METPE  E=3e-12 s/c=0.43 id=36% cov=24%
-ERIAVALSGGKDSTVLLWLMnmllgKRAADRLVAITVDEGIRDYRDetLAAARRLTHRLGIR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q18E64(82-228:371) tRNA methyl transferase n=8 Tax=Halobacteriaceae RepID=Q18E64_HALWD   E=4e-12 s/c=0.51 id=28% cov=28%
---VLVAFSGGVDSAVVATLAYDAlGSNAIACTAKSETLPAAELEDAHQVAAEIGL-PHKIVSFSELND-------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q2LUY4(45-190:296) GMP synthase (Glutamine-hydrolyzing) n=21 Tax=Bacteria RepID=Q2LUY4_SYNAS  E=4e-12 s/c=0.51 id=28% cov=60%
-----VAFSGGVDSTFLLWAAREAlGDSVTALTASAPYMPKEEICEAGRIAETIGVRH-------------------AVLEIPLNEEIRFNPDDRCFRCKRQLFSAMKAE-ADQRGIPSVLDGSNLDDL---QDYRPG-MKALKEL---------KVPSPLLEqrWRKKEIRKIGREIG-------------------------------------------------------
>UniRef50_D0MEN6(249-433:554) Asparagine synthase (Glutamine-hydrolyzing) n=1 Tax=Rhodothermus marinus DSM 4252 RepID=D0MEN6_RHOM4  E=6e-12 s/c=0.40 id=30% cov=24%
-RRVAVLLSGGVDSTLLAKALVDRGLEVTGYCV--GQPEASDVQLVKRLARTLGLSVH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B9LAC4(2-167:319) Thiamine biosynthesis protein:ExsB n=2 Tax=Nautiliaceae RepID=B9LAC4_NAUPA  E=1e-11 s/c=0.44 id=29% cov=24%
--KAIALFSGGLDSALAIKLIQEQNIEIEGVYIDVGFETNKQKtEHLQKLADELGIK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B2IGB5(83-241:400) tRNA(Ile)-lysidine synthetase n=2 Tax=Beijerinckiaceae RepID=B2IGB5_BEII9  E=3e-11 s/c=0.45 id=25% cov=44%
-RKVLLAVSGGPDS-VALMLLAAQWAEAVwkapplsVASVDHGLRPDSlaEAEQVAEWAARLGLPHHI------LRWEGEKPKTRLQERARDARYG------------------LLIAHAETIGADYLVTAHHADD--------------------------------------------------------------------------------------------------------
>UniRef50_B3E103(22-170:307) tRNA(Ile)-lysidine synthase MesJ n=1 Tax=Methylacidiphilum infernorum V4 RepID=B3E103_METI4  E=5e-11 s/c=0.47 id=28% cov=23%
---VLCGISGGVDSIVLLHSLVETGKRPIVLHFQHGWRQDEESDAklVEETAKELGVE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A5DFK7(24-193:471) Putative uncharacterized protein n=2 Tax=Pichia guilliermondii RepID=A5DFK7_PICGU  E=2e-10 s/c=0.40 id=34% cov=22%
-RRLAIALSGGVDSMCLAYLLSQYKqvyepsLELHSITIDHGYRSDSEIE-AQKVAQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q1ATZ7(23-166:444) tRNA(Ile)-lysidine synthetase-like protein n=1 Tax=Rubrobacter xylanophilus DSM 9941 RepID=Q1ATZ7_RUBXD  E=2e-10 s/c=0.47 id=32% cov=23%
--RPLALVSGGPDSVALLRALVGLGYEPAVLHVDHGLRgeeSRGDAEFVRELCRGLG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C5VKF6(22-167:456) tRNA(Ile)-lysidine synthetase n=2 Tax=Prevotella RepID=C5VKF6_9BACT   E=2e-10 s/c=0.47 id=25% cov=25%
----LVALSGGADSVALLLCIKELGYRVEAVHCNFHLRGEeslRDEQFCEDLCQRENIPLHKV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C0R4S1(21-181:431) tRNA(Ile)-lysidine synthase n=11 Tax=Wolbachia RepID=TILS_WOLWR   E=3e-10 s/c=0.42 id=28% cov=26%
---VAVAVSGGVDSIVLLHLMtnwakKNKLSLPTALTVNHGLRPEsqKEADFVVSYAKELGAKESFILN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B6BIH0(13-160:333) tRNA(Ile)-lysidine synthetase n=1 Tax=Campylobacterales bacterium GD 1 RepID=B6BIH0_9PROT  E=3e-10 s/c=0.46 id=31% cov=26%
-KKNLLAFSGGADSTALFFLLLKQNIKFDIAIVNYNERVQsiKEVEYAKELASKYNLECHTLV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A9AY39(380-536:622) NAD+ synthetase n=1 Tax=Herpetosiphon aurantiacus ATCC 23779 RepID=A9AY39_HERA2  E=3e-10 s/c=0.43 id=23% cov=26%
FKQVVIGLSGGVDSALTTYLCAKAFgaENVLAVRMPYRTSSSDSLDHAQLVIDDLGIQHRTI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C9RPN2(219-394:611) GMP synthase, small subunit n=1 Tax=Fibrobacter succinogenes subsp. succinogenes S85 RepID=C9RPN2_FIBSS  E=3e-10 s/c=0.38 id=18% cov=74%
-RKVFLLVSGGVDSTVAFVLLNRvLGPEkVLGLHVDNGMMRLGESQKIMDFLTKEGMNNLKIRDASKHFLAKLKGVTAPETKRGIIGKEFLTVKDEEMAKLNLDpnewMMAQGTIYPDTIESGG---TKNADKIKTHHNRVQEVLDLMEKGL---------VLEPLADLYKDEVRALGE---ELGIPHNLVW---------------------------------------------
>UniRef50_A2SQD8(13-162:251) ExsB family protein n=1 Tax=Methanocorpusculum labreanum Z RepID=A2SQD8_METLZ  E=1e-09 s/c=0.44 id=21% cov=65%
---ALVALSGGTDSMTLLAAFVKEGGPVSAATIRSEFTPPDEVTRAEHFARRLGVNWTVI-----------------DVSVLSKENLRFNPQDRCYICKKLIMKKML----EAADGKTVCDGTHADDAAEERPGRKAL-------------KELGIVSPFalAGIGKKEIYALAK---ELGVPVIPSSSC-------------------------------------------
>UniRef50_A9A3V0(23-240:251) Asparagine synthase n=1 Tax=Nitrosopumilus maritimus SCM1 RepID=A9A3V0_NITMS  E=1e-09 s/c=0.30 id=25% cov=26%
-KKIGIAYSGGVDSTLISKICKDMDYDITLLTI--GFAESHDILFAKEVNEQLN-YPHHILEI------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C0ZHF7(19-194:475) Putative tRNA(Ile)-lysidine synthetase n=1 Tax=Brevibacillus brevis NBRC 100599 RepID=C0ZHF7_BREBN  E=2e-09 s/c=0.37 id=35% cov=25%
---VVVGISGGNDSTALLHILASLNKqyqyqwKLHAVHLNHGFRgeeARQDALYAEELCRELGVVFHL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_O27071(17-163:338) Conserved protein n=1 Tax=Methanothermobacter thermautotrophicus str. Delta H RepID=O27071_METTH  E=3e-09 s/c=0.44 id=40% cov=28%
-ERIAVGFSGGADSTALLDMAADVADTVVAFTVDTGVMPRGFIEGASGIAREIGVE-HVVLEMNLL---------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C1XLL9(273-360:611) Asparagine synthase, glutamine-hydrolyzing n=1 Tax=Meiothermus ruber DSM 1279 RepID=C1XLL9_MEIRU  E=4e-09 s/c=0.73 id=39% cov=24%
-----VSLSGGLDSSLVAALAAQQHERVVGFCYGHPQAPRSEGPLARELAQKAGIDVHFV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B1I340(39-188:307) PP-loop domain protein n=2 Tax=Clostridia RepID=B1I340_DESAP   E=5e-09 s/c=0.42 id=35% cov=23%
-------VSGGKDSTALLYILayLRDYshlrFELEAVMLDLGW-GEVDFEPHREFCRRLGVPLHI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6FY47(28-174:277) Putative uncharacterized protein n=1 Tax=Plesiocystis pacifica SIR-1 RepID=A6FY47_9DELT  E=5e-09 s/c=0.43 id=26% cov=61%
----VTAFSGGVDSTLVAVVAARvHGERALAVTGVSPSLAESERAFASRVAAELGLRHRLVDTHEIERAGYQANAGD-----RCYHCKTELFERLVV-------------LAKAEGFACVVSGDNLDDLGGH---RPGMLAAEENAVRK----------PLIeaELGKDQIRALARHLG-------------------------------------------------------
>UniRef50_Q0W864(50-215:308) Predicted ATPase (PP-loop superfamily) n=6 Tax=Euryarchaeota RepID=Q0W864_UNCMA  E=1e-08 s/c=0.38 id=30% cov=24%
-----VAMSGGKDSAVTLSILVDTFttrsnIKFSAITVDEGIEgyRNESIPYAKELCDRLGVPHYVV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A3TZ17(23-172:414) PP-loop family protein n=2 Tax=Rhodobacteraceae RepID=A3TZ17_9RHOB   E=1e-08 s/c=0.42 id=38% cov=24%
-----VAVSGGSDSLALLHLLHDwasgSGLALHAVTVDHGLRADSAAEAACvgEIAGRLGV-PHTVL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C7REW1(21-205:285) PP-loop domain protein n=3 Tax=Anaerococcus RepID=C7REW1_ANAPD   E=2e-08 s/c=0.33 id=23% cov=28%
-EKFVLAFSGGVDSSLILKLAsmyREEKNDVVAIMYNTNTTPDGDLENSQNLACEMDV-DLKVVDIDVF---------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q72IF6(20-171:507) tRNA(Ile)-lysidine synthase n=3 Tax=Bacteria RepID=TILS_THET2   E=3e-08 s/c=0.40 id=31% cov=22%
----VLAVSGGGDSVALALLVKEAGRQAVVAHLDHGLRPESPLDQAfvRALAERLG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q9HKF1(1-116:402) Argininosuccinate synthase n=4 Tax=Thermoplasmatales RepID=ASSY_THEAC  E=3e-08 s/c=0.52 id=25% cov=49%
MDKALLLYSGGLDTSVMIKWIQEnLSMDVATLTLNVG---NSDLVAIEEKARMLGADPVFVHDAK--DEFAEKFIAKSIMANGSY----EGYPLSTALARP-LMAEKAVKYAQKIGAKYIVHG-------------------------------------------------------------------------------------------------------------
>UniRef50_C5RD28(26-188:324) Possible tRNA(Ile)-lysidine synthetase MesJ n=1 Tax=Weissella paramesenteroides ATCC 33313 RepID=C5RD28_WEIPA  E=4e-08 s/c=0.37 id=23% cov=46%
---VLVAVSGGQDSLRLLRWLtagdlpKDLQPQVSAIYINHQLRSDAQQEEA-LVRKVFAHTPHL---------QSATIRKLDWSEVPTVSVEEKAREK-----RYGVMFSV----AEQVGANSIVTAHHRND--------------------------------------------------------------------------------------------------------
>UniRef50_Q296T3(4-143:419) Argininosuccinate synthase n=4 Tax=Drosophila RepID=Q296T3_DROPS   E=6e-08 s/c=0.43 id=33% cov=26%
-ETVILAYSGGLDTSCILKWLLDQQYNVICVLADVGQKE--DFAAAEKKALNIGANKVIVVD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A1RYP4(49-171:328) PP-loop domain protein n=1 Tax=Thermofilum pendens Hrk 5 RepID=A1RYP4_THEPD  E=7e-08 s/c=0.49 id=38% cov=24%
-ERVAVAVSGGKDSLTTLYLfsrfAGELGVEVFGVAVDEGIAGYREykLEALRSLAGRLGVE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C6X0I5(22-173:434) tRNA(Ile)-lysidine synthetase n=2 Tax=Flavobacteriaceae RepID=C6X0I5_FLAB3  E=8e-08 s/c=0.39 id=23% cov=25%
--RYLLAVSGGVDSMVLLYLFSHSNLEFEVAHVNYRLR-GVDSDADQRIVEEFCAKHHL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C7DBG3(32-182:422) tRNA(Ile)-lysidine synthase n=1 Tax=Thalassiobium sp. R2A62 RepID=C7DBG3_9RHOB  E=8e-08 s/c=0.39 id=41% cov=25%
-----VAVSGGSDSTALLLacveWAKSNGVAVHAVTVDHGQRveAKQEAIAVSELTAELGVE-HSILTL------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B7G6Z6(415-586:770) Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1 RepID=B7G6Z6_PHATR  E=9e-08 s/c=0.35 id=22% cov=25%
-RKIIISLSGGVDSmviaSALAHLRRSLGYNlqLTAVHIDYANRPdsKAEASYVERYCQQLEIEYH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6LBU3(21-175:438) tRNA(Ile)-lysidine synthase n=22 Tax=Bacteroidales RepID=TILS_PARD8   E=9e-08 s/c=0.38 id=24% cov=25%
---VLVGLSGGADSVALLGVLVRLGYPCIALHCNFhlrGEESDRDEAFACEFAESLEVPFHKI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D2RE98(50-220:308) PP-loop domain protein n=1 Tax=Archaeoglobus profundus DSM 5631 RepID=D2RE98_ARCPR  E=1e-07 s/c=0.35 id=27% cov=26%
--RIAIALSGGKDSVTLTYVLhkflsKRRDVELFAITVDEGIEGYRppTVKIARKITSELGIE-HIIV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C0YLD6(265-392:610) Putative uncharacterized protein n=1 Tax=Chryseobacterium gleum ATCC 35910 RepID=C0YLD6_9FLAO  E=1e-07 s/c=0.46 id=27% cov=24%
---VAVMMSGGIDSTLIAYKSKSYNADINAYTISYPF-SEEEVKNAALAAQHFGV-SHEV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A1ZJJ3(221-287:563) Asparagine synthase family n=1 Tax=Microscilla marina ATCC 23134 RepID=A1ZJJ3_9SPHI  E=1e-07 s/c=0.88 id=27% cov=24%
-----VFLSGGLDSSILAArVAQLSSKKIHTYSIHFGKKYRNELHYAQKVAQRYQTQHHEV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q2FSW6(28-184:245) NH(3)-dependent NAD(+) synthetase n=1 Tax=Methanospirillum hungatei JF-1 RepID=Q2FSW6_METHJ  E=2e-07 s/c=0.37 id=19% cov=67%
----VIGLSGGIDSAVAAALCVRaAGSDmVQGFFLPSAVTPSEDAADVRLLAESLHIPVMTIPIGPVIDQYRR---------MPDFTENSYLVGNLMARTRMTMLYYYANQM------NRLVCGTS---------NYTEYLLGYCTKFGDNAAD----VQPIMHLLKTQVWDLARYLGLPQKVIEKT----------------------------------------------
>UniRef50_P08243(251-318:561) Asparagine synthetase [glutamine-hydrolyzing] n=48 Tax=Eumetazoa RepID=ASNS_HUMAN  E=3e-07 s/c=0.85 id=30% cov=26%
-RRIGCLLSGGLDSSLVAATLLKQLKEAqvqYPLqTFAIGMEDSPDLLAARKVADHIGSEHYEVL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q5HSX8(15-159:321) tRNA(Ile)-lysidine synthase n=15 Tax=Campylobacter RepID=TILS_CAMJR   E=4e-07 s/c=0.40 id=23% cov=24%
--KNLLAFSYGSDSSALFYLLMQEKIDFDLVMINYKTRKNSDLEELK--AKELALKFHK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q92JY3(20-186:453) tRNA(Ile)-lysidine synthase n=3 Tax=Rhizobiaceae RepID=TILS_RHIME   E=5e-07 s/c=0.34 id=27% cov=24%
-RRILVAVSGGSDSmglLVALHSAIaadeRRGFSLAACTVDHALRPQSacEAEDVAAFCAALGI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q6L1K5(152-363:470) Putative uncharacterized protein n=1 Tax=Picrophilus torridus RepID=Q6L1K5_PICTO  E=5e-07 s/c=0.27 id=17% cov=85%
--RVAIMSSGGKESLLGYGILNEIGAETYAFYFEESGSHWLTAKTAYDYYSRHFKNVFKIWSNVDRFYKFMN-LKLKIIDKSKINIRADDYPIQVFIFPVYIFSMI--PFMKKYGIGNIVMGDEFDDpremklfhgmkyYYGIFDQTVDFNDMMTDYFK-STGKDIdvySIVYP-ITGSLEEKILMERYHDLFLNQRSC-HSCHiKDGRILPCGKCTKC----------------------------
>UniRef50_A0B9G6(2-156:199) Conserved hypothetical ATP-binding protein n=1 Tax=Methanosaeta thermophila PT RepID=A0B9G6_METTP  E=8e-07 s/c=0.36 id=34% cov=24%
--KVTTLFSGGKDSGLTAILLEPFFDEIELVTFSFGQDRAWEV--AARAARAIG-HPHRV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C6C0L2(257-320:623) Asparagine synthase (Glutamine-hydrolyzing) n=1 Tax=Desulfovibrio salexigens DSM 2638 RepID=C6C0L2_DESAD  E=1e-06 s/c=0.87 id=23% cov=23%
------LLSGGVDSSLVVALMAEAGSKsIDTFTIGFHEKKYDESGHAAKVAKHLGVNHH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B9L8Y0(236-313:566) Asparagine synthase (Glutamine-hydrolyzing) n=1 Tax=Nautilia profundicola AmH RepID=B9L8Y0_NAUPA  E=1e-06 s/c=0.71 id=22% cov=23%
------LLSGGVDSSLIAAMMSKYG-KIKTFSIGYdGYENYDERRYARLTAEHIGSEHYEI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C5F116(265-321:628) Asparagine synthase n=2 Tax=Helicobacter RepID=C5F116_9HELI   E=1e-06 s/c=0.97 id=24% cov=24%
-----VCLSGGVDSSLVCAVLKDAGYSFDTFSISFLEASYDEGHYAEEVARVLGVKNHR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A3JPX5(28-178:419) PP-loop family protein n=1 Tax=Rhodobacterales bacterium HTCC2150 RepID=A3JPX5_9RHOB  E=2e-06 s/c=0.37 id=34% cov=24%
-----VAVSGGSDSMALLvlanAWAIENGHVLYVVTVDHQLRPdaRVEAETVGDFCSTLGL-PHQVL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A1RQG9(38-204:304) PP-loop domain protein n=3 Tax=Pyrobaculum RepID=A1RQG9_PYRIL   E=2e-06 s/c=0.33 id=38% cov=24%
-----VAVSGGKDSCAALALLKEYieeyriDAEVRAFHINLGFRTSAKIEEAvRTLAEALGVGIHVV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q8TUL5(207-272:590) Predicted protein n=2 Tax=Methanosarcina RepID=Q8TUL5_METAC   E=2e-06 s/c=0.83 id=28% cov=23%
-KRLIVPLSGGLDSRIIVGMLKRLGVN-DVICMSYGRKGSRESEISRHVAETLG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B9CZD8(20-168:332) tRNA(Ile)-lysidine synthase (TRNA(Ile)-lysidinesynthetase) (TRNA(Ile)-2-lysyl-cytidine synthase) n=2 Tax=Campylobacter RepID=B9CZD8_WOLRE  E=2e-06 s/c=0.37 id=33% cov=22%
----LLAFSHGVDSTALFYLLDEAGVKFDLAIVDYNVRAQSkdEITSARQLALKFN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B0UN38(31-215:417) Argininosuccinate synthase n=3 Tax=cellular organisms RepID=B0UN38_METS4  E=2e-06 s/c=0.30 id=22% cov=79%
---VVTMFSGGLDSSYLLHRLRGLGFaHVHAVAVDVG--APLDEPALRRAASLFGAEFVRLDGRGHFVEGHVRPAIRAHAKYLGIYPLSSSLSRPAI-------AELVARYARRVGADLILHTANLSQNSLPRLN--------NSLARLGFPGQYG--SPYeqSAISRQQKAAELAEAG-LGAMAERALS---GDENLWC----------REFESGPLDDP-------------
>UniRef50_A9A144(50-168:304) PP-loop domain protein n=2 Tax=Thaumarchaeota RepID=A9A144_NITMS   E=2e-06 s/c=0.46 id=30% cov=25%
---VAVAVSGGKDSLALLKIIHEmassHNFRIKTITIDEGIPgYRNEaLEIVEKFCGELGVE-HKV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A2U3E3(198-261:534) Putative uncharacterized protein n=1 Tax=Polaribacter sp. MED152 RepID=A2U3E3_9FLAO  E=2e-06 s/c=0.85 id=27% cov=23%
-KTVLLPLSGGYDSRLIAVLLKKHNYKNV-ICFTYGRKENFEIENSKKTAESL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q8TWD2(50-222:303) Predicted ATPase of the PP-loop superfamily implicated in cell cycle control n=1 Tax=Methanopyrus kandleri RepID=Q8TWD2_METKA  E=3e-06 s/c=0.32 id=32% cov=26%
--RIVVALSGGKDSSLALRLVTEYVEplpevEVIALTVDEGISGFRDacLRAAERVADELDVE-HEVV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A8UGA3(7-208:220) Putative uncharacterized protein n=1 Tax=Flavobacteriales bacterium ALC-1 RepID=A8UGA3_9FLAO  E=3e-06 s/c=0.27 id=19% cov=81%
-----VLWTGGWDSTFRVIQLYRLGATIQTIYIIDQKRksSNKEIEVINSLAEktplHFNQSNGHILPIKYIKRENIPYNLFLKVIHKILRRQVGLGKQYYW----------LASFAQKHKNLDVSFHKEDLDKFFSEEQLIEIKDDNFGSNWKINPKKVGFLRrqlfknmtfPLITVTKPEMKFIAEENNFIEL-MELTWFCHKST-DKPCGKCAPCK---------------------------
>UniRef50_A3VLU1(24-90:417) PP-loop family protein n=1 Tax=Rhodobacterales bacterium HTCC2654 RepID=A3VLU1_9RHOB  E=3e-06 s/c=0.81 id=40% cov=23%
----VVAVSGGGDSMALLHVAQAwgrtQGKAVSALTVDHGLRDEAATEAARvaEICADLGV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C6XND6(56-216:473) tRNA(Ile)-lysidine synthetase n=1 Tax=Hirschia baltica ATCC 49814 RepID=C6XND6_HIRBI  E=4e-06 s/c=0.34 id=26% cov=25%
-KRIGIAVSGGSDSLgllcLSAEWAKLNNWHLQALTIDHGMRPEaaQEAVYVQSICETLNI-PHT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C8QZJ8(229-390:543) Asparagine synthase (Glutamine-hydrolyzing) n=1 Tax=Desulfurivibrio alkaliphilus AHT2 RepID=C8QZJ8_9DELT  E=4e-06 s/c=0.33 id=28% cov=23%
-------CSGGLDSSLIAAIAAEEIPNLH--TFAVGMRdengkESDDLTAARLVAEHIDSTHHELI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q4AC05(232-382:608) 117M18_15 n=2 Tax=Brassica RepID=Q4AC05_BRACM   E=6e-06 s/c=0.35 id=31% cov=23%
-----VLLSGGLDSSLVASVAIRHleksdarqwGSKLH--TFCIGLKGSPDLKAGKEVADYLGTRHHEL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A8G8L6(261-368:610) Asparagine synthase (Glutamine-hydrolyzing) n=1 Tax=Serratia proteamaculans 568 RepID=A8G8L6_SERP5  E=6e-06 s/c=0.50 id=35% cov=23%
------MLSGGLDSSLITAIACRQGRR-ELKTFAVGFNESafSELDYSRRLAKDLGTEHH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A8ACD0(93-157:389) Phosphoadenosine phosphosulfate reductase n=1 Tax=Ignicoccus hospitalis KIN4/I RepID=A8ACD0_IGNH4  E=7e-06 s/c=0.82 id=26% cov=23%
--KVVLNFSGGKDSVAAAKVLSDLGADVTLLysHVSYLENPRN-VDFVEKVANRLGVK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B9JRY3(46-203:454) Putative uncharacterized protein n=1 Tax=Agrobacterium vitis S4 RepID=B9JRY3_AGRVS  E=9e-06 s/c=0.33 id=36% cov=25%
--RLLVAISGGSDSTGLLLALHEQlqampakTVTLHAATIDHGLRdgSAAEAETVAALCATLGI-PHEI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q8U2P1(200-261:536) Putative uncharacterized protein n=1 Tax=Pyrococcus furiosus RepID=Q8U2P1_PYRFU  E=1e-05 s/c=0.85 id=33% cov=21%
----VIPLSGGYDSRAIATMLKKNGYENVILY-TYGKPDSTEVRVAREVAKNL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A5UJI7(235-450:475) Asparagine synthetase, AsnB n=3 Tax=Methanobrevibacter smithii RepID=A5UJI7_METS3  E=1e-05 s/c=0.24 id=29% cov=24%
-----VIFSGGVDSSLIALLLREislnKNLKVTLYAV--GKKDSKDVVAAKCVAEYLGL-PLKVHDI------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C7LW25(33-194:334) tRNA(Ile)-lysidine synthetase n=1 Tax=Desulfomicrobium baculatum DSM 4028 RepID=C7LW25_DESBD  E=1e-05 s/c=0.33 id=30% cov=23%
--RLVVAYSAGLDSTALLHLLhllrAPLNLTLIAAHAHHGLRPEsdRELEHAREVCSRLSI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q0FAG4(33-179:423) PP-loop family protein n=1 Tax=Rhodobacterales bacterium HTCC2255 RepID=Q0FAG4_9RHOB  E=1e-05 s/c=0.36 id=28% cov=22%
-------VSGGGDSIALLYltkeWACKNDKKIFVATVDHGLRKESlnEAQTVKDICRSLGIE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C9YE40(31-190:318) tRNA 2-thiocytidine biosynthesis protein ttcA n=1 Tax=Curvibacter putative symbiont of Hydra magnipapillata RepID=C9YE40_9BURK  E=1e-05 s/c=0.33 id=23% cov=47%
--RVMVCMSGGKDSYgmldILLKMQQRApiNFEIVAVNLDQKQPGFPDHILPEYLAK-LGVEFHIETQ-------------DTYSIVKRNIPEGKTMCSLCSRLRRGILYSV----ARKLKCNKLALGHHRDD--------------------------------------------------------------------------------------------------------
>UniRef50_Q1QE23(309-462:567) NAD+ synthetase n=5 Tax=Moraxellaceae RepID=Q1QE23_PSYCK   E=1e-05 s/c=0.34 id=29% cov=23%
----IVGLSGGIDSALTLCIAVDAlgADKVYAVMMPYEYTSQISLEDAQAQARRLNV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q72C25(22-186:347) tRNA(Ile)-lysidine synthase n=3 Tax=Desulfovibrio vulgaris RepID=TILS_DESVH  E=1e-05 s/c=0.32 id=31% cov=23%
----VVALSGGADSTALLlilhYLRQRLGLSLSALHVDHGLRPESaaEARAAVTFCHALGI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q72LF3(48-163:321) Veg136 protein n=3 Tax=Thermus RepID=Q72LF3_THET2   E=1e-05 s/c=0.45 id=20% cov=24%
-ERVLVAVSGGKDSLALWDVLSRLGYQAVGLHIELgiGEYSKRSLEVTQAFARERGLE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q21PG9(280-332:652) Asparagine synthase, glutamine-hydrolyzing n=1 Tax=Saccharophagus degradans 2-40 RepID=Q21PG9_SACD2  E=2e-05 s/c=0.98 id=26% cov=23%
-------LSGGIDSTVVSAVLQANtSTAIDTFTIGFEEKSFNEAEFAKEIAKHLGTKHHE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_P03766(4-191:290) Uncharacterized nin region protein ORF290 n=11 Tax=root RepID=Y290_LAMBD  E=2e-05 s/c=0.28 id=31% cov=23%
----VVSFSGGRTSAYLLWLMeqkRRAGKDVHYVFMDTGCEHPMTYRFVREVVKFWDI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B4S4F3(9-213:243) Putative uncharacterized protein n=1 Tax=Prosthecochloris aestuarii DSM 271 RepID=B4S4F3_PROA2  E=2e-05 s/c=0.25 id=20% cov=81%
-----LLWSGGWDSTFrLCDLLLVQDRRVRLYYvVDPGrQSVAQEIKAMQRIRKRLQERiasfdtRLLSMQVVWLWEIAPESSMTSRYESLRKRFKSFGPQYEWL-----------GRFVAEQGIGDLelsIESNSFRPNGPLWSALEDMLVEEERNFRLCDNPSDPdfeffrsFRFPLIKTTKLAMMHYAKEHG-FDDIMFQSWFCHTPHNGRPCGICHPC----------------------------
>UniRef50_A8LCH5(224-371:486) ExsB family protein n=16 Tax=Actinomycetales RepID=A8LCH5_FRASN   E=2e-05 s/c=0.35 id=35% cov=23%
---VLVAFSGGADSAfLLAAAARELGPDaVVAATAVSASLPAAELDAARRFATGLGVR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B2J2T3(253-377:584) Asparagine synthase n=10 Tax=Cyanobacteria RepID=B2J2T3_NOSP7   E=2e-05 s/c=0.42 id=25% cov=26%
-----VFLSGGLDSSCITALAAKfHKAPVHTFSIHFGSECPNELEFSSLVASHC-QTQHHILEITF----------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A8ESL9(262-390:632) Asparagine synthetase n=2 Tax=Epsilonproteobacteria RepID=A8ESL9_ARCB4  E=2e-05 s/c=0.40 id=28% cov=22%
-----VFLSGGYDSSLVAsILAKKQGKKINTFTIGFDDKKYNEAEHAKTIAEYLG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1U3N3(41-101:336) tRNA(Ile)-lysidine synthetase n=1 Tax=Desulfovibrio aespoeensis Aspo-2 RepID=D1U3N3_9DELT  E=2e-05 s/c=0.84 id=33% cov=24%
-KTLAVGLSGGADSTALLlclhWLAVKNGGRVVAAHLNHRLRPEADDDArwAASLCESLGV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1N526(202-267:557) Asparagine synthase n=1 Tax=Victivallis vadensis ATCC BAA-548 RepID=D1N526_9BACT  E=3e-05 s/c=0.77 id=29% cov=25%
--RLVLPLSGGYDSRLIANYLYRLGVR-DVLCFSYGTSDDtTEVPISREVARRLNYEWHFV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C1FDB6(308-450:620) B-type asparagine synthetase chloroplast n=2 Tax=Micromonas RepID=C1FDB6_9CHLO  E=3e-05 s/c=0.36 id=29% cov=24%
-----LLLSGGLDSAVISTIIKPMLEETkqQFITFTVGQEGSPDITAARMMSEHLGTDHHE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q1R016(30-120:430) tRNA(Ile)-lysidine synthetase-like protein n=1 Tax=Chromohalobacter salexigens DSM 3043 RepID=Q1R016_CHRSD  E=4e-05 s/c=0.56 id=33% cov=22%
-----VALSGGLDSSLLLTLAVAACRRhprpLYAVHVNHGlQDAAADFEAhARWLCGRLGV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q2KC64(258-311:613) Asparagine synthetase (Glutamine-hydrolyzing) protein n=1 Tax=Rhizobium etli CFN 42 RepID=Q2KC64_RHIEC  E=4e-05 s/c=0.94 id=30% cov=23%
---VAVALSGGIDSSLVAALTARHFPgQLHAFTIGYkGRPDTDERGFAATLAKELGI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q7MR31(17-161:326) tRNA(Ile)-lysidine synthase n=1 Tax=Wolinella succinogenes RepID=TILS_WOLSU  E=4e-05 s/c=0.35 id=31% cov=22%
--KNLLGFSGGVDSTALFFLLLEREIPFDIALVNYHQRaqAKEEESYAKELAHR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C9YE00(5-76:82) Putative uncharacterized protein (Fragment) n=2 Tax=Proteobacteria RepID=C9YE00_9BURK  E=5e-05 s/c=0.70 id=56% cov=22%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------WINKAQTWELAHELGErsgvpeggqalVDLVVEHTHTCYLGDRthrhawGYGCGTCPACELRAKGY---------------------
>UniRef50_C7N0A0(241-386:512) Asparagine synthase (Glutamine-hydrolyzing) n=3 Tax=Actinomycetales RepID=C7N0A0_SACVD  E=6e-05 s/c=0.34 id=35% cov=23%
------VLSGGIDSSSVVALASGGGRPVR--TISLGTDIGDEFAAARVVAEHLGTRHHE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A5IZI7(2-150:286) Putative uncharacterized protein n=1 Tax=Mycoplasma agalactiae PG2 RepID=A5IZI7_MYCAP  E=7e-05 s/c=0.34 id=25% cov=21%
--------SGGPDSMYLLDLISSQRSDIVVATVNYNvrQDSAYDVEIVRKFCEDKGI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q30XB0(261-314:618) Asparagine synthase, glutamine-hydrolyzing n=1 Tax=Desulfovibrio desulfuricans subsp. desulfuricans str. G20 RepID=Q30XB0_DESDG  E=8e-05 s/c=0.92 id=31% cov=23%
-----VFLSGGIDSTlVAARLAQRHSRSIPAFTIGYKESDFSELPYAQHAADKLGLK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q3J9U0(232-287:581) Putative uncharacterized protein n=2 Tax=Nitrosococcus oceani RepID=Q3J9U0_NITOC  E=8e-05 s/c=0.89 id=33% cov=23%
-KKVLpartaLSLSAGLDSRTALAYLQRAGVEVSFYTF--GQPGSTEVIGAQSIAQRVG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C9RI80(37-202:292) Queuosine synthesis-like protein n=1 Tax=Methanocaldococcus vulcanius M7 RepID=C9RI80_METVM  E=0.0001 s/c=0.30 id=16% cov=67%
----VVMASGGKDSSTAIALARDIGLNIrYLIHFYHRWSWEISKNMVMALSEKYNIPAVFFDITDEI-----------------LKRTRGAKGSSICRICKNIMKDKTVDFAREKGIKIIMTGDSALEkvsGAVMNYLRERYgevkYDKMELTpvpQKYSKTKEILFFRPLIRLSYDDVLRLTRYY--------------------------------------------------------
>UniRef50_A9D391(35-185:444) Putative uncharacterized protein n=1 Tax=Hoeflea phototrophica DFL-43 RepID=A9D391_9RHIZ  E=0.0001 s/c=0.33 id=29% cov=23%
-----VAVSGGSDSLGLLLGMARSvpPKQLVALTVDHGLRsgSADEARTVKRICRRLGVR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B0UGN1(32-185:344) tRNA(Ile)-lysidine synthase n=7 Tax=Alphaproteobacteria RepID=TILS_METS4  E=0.0001 s/c=0.32 id=35% cov=23%
-------VSGGPDSTALMGCAAALPPRVPVLvaTVDHGLRPESGEEAAgvAALAGRLGL-PHRIL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C7M2H1(319-381:571) NAD+ synthetase n=1 Tax=Acidimicrobium ferrooxidans DSM 10331 RepID=C7M2H1_ACIFD  E=0.0001 s/c=0.77 id=31% cov=23%
---ALVAVSGGIDSALVATIAVDAlGPDALTL-VALPSRYSSEgsLRDARLLADRLGV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C4WHU8(23-197:463) tRNA(Ile)-lysidine synthetase n=1 Tax=Ochrobactrum intermedium LMG 3301 RepID=C4WHU8_9RHIZ  E=0.0001 s/c=0.28 id=26% cov=25%
---VIAAVSGGSDSLGLLFLLrdymamLKDPPRLIAATVDHQLRAESrdEAENVGRLCSHYGIE-HRIL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D2B1Z0(259-335:638) Asparagine synthase (Glutamine-hydrolyzing) n=1 Tax=Streptosporangium roseum DSM 43021 RepID=D2B1Z0_STRRD  E=0.0002 s/c=0.63 id=24% cov=24%
-------LSGGVDSSaVVAAMAMQSSEPVKTFSIGFEDSRYDERHKARMVADRYSTDHHELV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A1AWM5(45-246:263) PP-loop domain protein n=2 Tax=sulfur-oxidizing symbionts RepID=A1AWM5_RUTMC  E=0.0002 s/c=0.24 id=18% cov=63%
--KILLAVSGGKDSLSLFHILRHFlasapiSFELGVVTID-PQVDGFEPQALKSFFKKFDVP----------------YFFESFPIMKQAEKSMKGNSYCSFCAR--IKRGLMYQVARREGYNVLALGQHLDDLAEsliMSICHNGKIQTM-KAHYINDAKDLRIIRPLAYVRERQ----------------------------------------------------------------
>UniRef50_B4DAH3(280-335:661) Asparagine synthase (Glutamine-hydrolyzing) n=1 Tax=Chthoniobacter flavus Ellin428 RepID=B4DAH3_9BACT  E=0.0002 s/c=0.87 id=30% cov=23%
-----VFLSGGIDSSAVAALAAKHvpagQLNTFAIGFNEPSF--DESAHARFVAERLGTRHHE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q9R8E3(245-298:513) Carboxyethyl-arginine beta-lactam-synthase n=3 Tax=Streptomyces RepID=BLS_STRCL  E=0.0002 s/c=0.90 id=29% cov=24%
----LVVLSGGIDSSGVAACAHRAAGELDTVSM--GTDTSNEFREARAVVDHLRTRHREI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1ZA28(41-207:789) Whole genome shotgun sequence assembly, scaffold_14 n=2 Tax=Sordariaceae RepID=D1ZA28_SORMA  E=0.0002 s/c=0.29 id=21% cov=51%
-RQVACAISGGVDSMALAFLFNRLKQDthslissgpsmeafrisdnilnkVRAVIIDHGLREGSD-EEARKVAN--------VIRTKFPDFLYPVIEPINWRSELGPGVDPKTQPNIETLGRKLRYVAFASA-CRSYNAVSLFTAHHEDD--------------------------------------------------------------------------------------------------------
>UniRef50_C3YSG5(234-298:539) Putative uncharacterized protein n=1 Tax=Branchiostoma floridae RepID=C3YSG5_BRAFL  E=0.0003 s/c=0.73 id=25% cov=25%
----LSLMKGGLDSSLISALLLKHAKKsgiIYPVqTYAIGMEGSPDVEAARTVAKYIGSEHHEV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6LSX1(4-74:220) Putative ATP binding protein n=4 Tax=Clostridium RepID=A6LSX1_CLOB8  E=0.0003 s/c=0.67 id=24% cov=24%
-EKVVVSFSGGKDCTLALYRMIKSGYKIIGLLVTFESKkdsyfHKIPRNVFQDISKELGI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B4D2G3(257-341:609) Asparagine synthase (Glutamine-hydrolyzing) n=1 Tax=Chthoniobacter flavus Ellin428 RepID=B4D2G3_9BACT  E=0.0003 s/c=0.56 id=33% cov=23%
-----VALSGGLDSAAIAALAARHYPGVlHAFSIGYPGRpPSDERADAKAFADRLGVPFH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C3XJP1(13-160:334) tRNA-lysidine synthase n=1 Tax=Helicobacter winghamensis ATCC BAA-430 RepID=C3XJP1_9HELI  E=0.0003 s/c=0.32 id=32% cov=22%
-KRNLLAFSAGVDSSALYFLLRECGISFDIAIVDYGIRkqSRLEVDRAKTLC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A0L551(261-340:609) Asparagine synthase (Glutamine-hydrolyzing) n=1 Tax=Magnetococcus sp. MC-1 RepID=A0L551_MAGSM  E=0.0007 s/c=0.58 id=27% cov=21%
-------LSGGLDSTSVAVGVKRLGHQLKAFSLGFPGHPRDESALAQATAERLG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6GFB8(281-336:930) Asparagine synthase, glutamine-hydrolyzing n=1 Tax=Plesiocystis pacifica SIR-1 RepID=A6GFB8_9DELT  E=0.001 s/c=0.82 id=33% cov=23%
-------LSGGLDSGLLAALLVEhAQGPVHTFTLADDPEH-PDLEAARTLAAKLGTVHHE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A2STX4(1-222:222) 7-cyano-7-deazaguanine synthase n=3 Tax=cellular organisms RepID=QUEC_METLZ  E=3e-54 s/c=0.96 id=30% cov=95%
MKKAVCLLSGGMDSTTLAFVAKKMGYDILALHVNYGQRTERkELEAAKKVADVLGVVEFLEISLDYFKKFGASSLTDMNIEVEAGVLGRADNPNTYVPFRNGNLISIATSYCESRDGEAIFIGVQSGDHTGYPDCTPRFIEAMQHAIYVGtqTEKSIELLTPFVMMNKTDILKEG---MELCVPYEHTWSCY-SENDEACGVCSSCLARLKAFADLGMEDPIPYKK--------
>UniRef50_Q1LTK2(7-237:238) 7-cyano-7-deazaguanine synthase n=234 Tax=Bacteria RepID=QUEC_BAUCH   E=3e-53 s/c=0.91 id=67% cov=100%
IKKTVVVFSGGQDSTTCLIQALTQYDQVYCITFDYGQRHRAEICIARRLTITLGAYDHQIIDTSALNVLAASSLTRENIIVPLAEKNHmNSSLSTFVPGRNIVFLTLAAIYAYQVKAEVIITGVCETDFSGYPDCREKFIQALNKAVNLGMAYNIHFISPLMWLNKAETWALADYYQKLDLVCNETLTCYNGIQGKGCGFCTSCSLRARGLETYKQQPKLTMSSLKAKTGL-
>UniRef50_A0LJR5(7-233:234) 7-cyano-7-deazaguanine synthase n=4 Tax=Bacteria RepID=QUEC_SYNFM   E=2e-52 s/c=0.91 id=39% cov=94%
-RKAVVLFSGGIDSTTCLAVAKAEGFEAYALSFFYHQRHGVEVEAARRSAPALGAREHLVLELP-LDRIGGSALTGHEEVPKDvpVEKMSDRIPATYVPARNTIFLSFALAWAEVLGAADIFIGVNALDYSGYPDCRPEYIAAFERMANLAIREtvegrmRIKVHTPLIRLTKGEIIKRGL---ELGLDYSLTHSCYDPDaRGLACGHCDSCILRKKGFMEAGIPDPTRY----------
>UniRef50_B8HQ99(2-229:229) 7-cyano-7-deazaguanine synthase n=1 Tax=Cyanothece sp. PCC 7425 RepID=QUEC_CYAP4  E=4e-51 s/c=0.89 id=33% cov=94%
--KIVILLSGGLDSTTVLYLARSLGHDCYALSFNYGQRHKQELAAAIAVAQLAGVIQHQVISFD-LGLWGGSALTDYTLDLPQNRafkEMAEQIPITYVPARNTIFLSFALSYAEAIGATQVYAGMNAIDYSGYPDCRPDYIAAMQEVYRLGTkqgreGEPIQIITPLIDLTKPAIIQLG---NRLGVPWAKTWSCYSDGGGNdppvACGVCDSCRLRLAAFAELSLTDPLPY----------
>UniRef50_Q8K986(1-227:232) 7-cyano-7-deazaguanine synthase n=1 Tax=Buchnera aphidicola (Schizaphis graminum) RepID=QUEC_BUCAP  E=1e-50 s/c=0.89 id=46% cov=99%
MKKILIIFSGGQDSTTCLIHYTNIYKEIYCITFDYNQLHKSEIDSARFISNYFNVKKHIFVDLKCLKNLSISSLTDEKISILDNHPLNFSLPSTFVPGRNILFLTLSSIYAFNHQINSIVLGVNEIDFSGYPDCRNAFLKKMNDVVQIGMNCKINFQSPLINLSKAEIWALSDYWNSTQFILNNTVTCYQGIQGKGCGQCQSCILRNDGFNKWKSNPSYYMKKLKEK----
>UniRef50_A0B6A6(1-224:224) 7-cyano-7-deazaguanine synthase n=4 Tax=Archaea RepID=QUEC_METTP   E=7e-50 s/c=0.89 id=27% cov=94%
MGRAVCLCSGGLDSTVAATIARRSGMDVYLIHVSYGQQAErREIEAIERIADAIGASDLMCSRIDLFRNISALTTQGARIPrGEEVSLDSESTPPTWVYCRNTVLLSMAAAYAEYLGAHSIYVGFNAEEAMSYPDNRPEFVEQFNALLEKAVAsfsRPPKVVAPLVDMRKKDIVRLGADI---KAPLELTWSCYLNGEI-HCGTCESCQHRRRGFVEAGIPDPTEY----------
>UniRef50_C8R2H0(18-258:258) ExsB protein n=1 Tax=Desulfurivibrio alkaliphilus AHT2 RepID=C8R2H0_9DELT  E=1e-49 s/c=0.82 id=40% cov=93%
---AVVLLSGGLDSTTVLALAKAAGYRCHCLSFRYGQRHTQELELARANARHWGAARHLILNI-ELDAIGGSALTGDELEVPkdnlspldspdgaetDAPGMAGEVPVTYVPGRNTIFLAYAASWAEVLGARDIFIGVNAVDFSGYPDCRPDYLEALAAALNLGSqcgreGRPFRLQAPLLHLSKAEIIAKGLA---LGVDYARTHSCYDPDqQHRACGRCDACILRRRGFAAAGCPDPTTY----------
>UniRef50_Q12WI3(2-223:233) 7-cyano-7-deazaguanine synthase n=6 Tax=cellular organisms RepID=QUEC_METBU  E=1e-48 s/c=0.88 id=29% cov=92%
--RSILLLSSGLDSVAALAIALDNSDVFMALTFDYGQRSvKKEIEYSRMVCEHYGIE-HRIITLSWLSSITNTSLVNKDLDVPELSINdlidgpdnitEDSAKSVWVPNRNGVFINIAASFAESHGCEYVIAGFNGEEAKTFPDNSKEFVNAVDECFSYSTANGVKVLAPLIDMDKVSIVRKA---MELGAPLEYSWSCYHGAE-EPCGVCESCMRRKRAFLASGFEDP-------------
>UniRef50_Q2N612(7-227:239) 7-cyano-7-deazaguanine synthase n=56 Tax=Bacteria RepID=QUEC_ERYLH   E=2e-48 s/c=0.88 id=36% cov=89%
-KAAAILLSGGLDSMVTAAIAQEQGYAVHALTIDYGQRHKVELQSARLIAAKIGAERH-VEIEADLRALGGSALTDDIDVPKCG--VGNDIPVTYVPARNLVFLSLTTAFAEASGARDIFIGVNALDYSGYPDCRPEFIESFAVTANLATkagveeSAPFKIHAPLQHMTKADI---ARECARLGLESAWSWSCYDPLPGlKPCGACDSCRLRRKGFAE-------------------
>UniRef50_Q5JHU5(1-234:239) 7-cyano-7-deazaguanine synthase n=6 Tax=Thermococcus RepID=QUEC_PYRKO  E=5e-46 s/c=0.79 id=29% cov=95%
MKRAVVLFSGGLDSTACLYWAKKNYDEVIMLTVNYGSNEEKVTNKVAEFFSKELDVPLKIVRLDFLEEFsklrgttlvGGETPKVTGEELENIEVAQETAKSVWVPARNVVLIAVAASLLDALGGGDIVVGFNAEEGATFPDNTPEFVEKMNEMLKYGTMAEVRVVAPLINLDKRGI---AKLLKELGAKYEYSNSCYMPkgftedGKPIHCGECESCVRRHRGLIEGIGEDKTVYA---------
>UniRef50_Q6WI28(2-224:238) ExsB protein n=1 Tax=Vibrio phage KVP40 RepID=Q6WI28_BPKV4   E=5e-44 s/c=0.80 id=28% cov=94%
--KVVSVLSGGLDSTILTYKLVDEFgkDNVFALSFYYGQKQSIELEKAKLTCQKLGIEHRLIDIsfLGEVVAPVCANIAGSDVAMPTIQdVLGDPQPPTEVPYRNMLLNTIAFSFAQANGCSAVFTGIQVHDAYGYWDCTQDFLDGMNKISALNRQHEITLHAPFAQMSKADEIAIGV---ELGVPFEDSLTCYDPNEaGESCGKCPSCAERIMNFGKAGIVDPAPYS---------
>UniRef50_A9A531(1-222:224) ExsB family protein n=2 Tax=Thaumarchaeota RepID=A9A531_NITMS   E=1e-43 s/c=0.80 id=35% cov=93%
MKKAVVVFSGGVDS-VCAVSFLKSKYELYGITFSYGQKANMEISATKSFAKKLGLKQHKIIDIGFMKELYGDSNVLTSSKRKIPSKFEYSI---VVPIRNAVFLSVASAWAYTLNASLVVYGAHTGD-KYYPDCRPAFAKKLESAFNQGeidginskIRKKIKIWSPYReGLSKSDLLKKGKKV--LGDSIFRTWSCYSN-KKLHCGVCESCNNRKIAFEKAGVTDKTKY----------
>UniRef50_Q6MKZ5(5-224:231) 7-cyano-7-deazaguanine synthase n=1 Tax=Bdellovibrio bacteriovorus RepID=QUEC_BDEBA  E=7e-42 s/c=0.78 id=28% cov=89%
-KKVVVLLSAGLDSTVNAYEAIKHHHEiVLALTFNYGQRaAKKELEASANIAKHLGI-PHKVVELPWFKDFNKSSLLVEDQAVPTGSaveidnqqKSEETAKSVWVPNRNGIFLNIAAAYAEALGADAVIPGFNAEEAATFPDNSREFLEQATKSLWYSTSNHVTVGCYTAHLKKPDIVRLGQ---GLKVPWELIWPCYFSG-DKWCGQCESCLRSKRAF---------------------
>UniRef50_C3XFP7(1-209:213) Queuosine biosynthesis protein queC n=1 Tax=Helicobacter bilis ATCC 43879 RepID=C3XFP7_9HELI  E=4e-41 s/c=0.81 id=25% cov=88%
MR--LVLFSGGVDSTTALFWSKKE-CATHALIFKYPSLHnKREIDAAVQICKDENVSYTLLDMSSVFVGFRSALLQNSSESIPQDSYNLESMAKLVVPFRNGIFLSVAAGLAESLGYKEIVLANHAGDHPLYPDCTQSFIDSMNESIMQGSGGAVKLCSPFCNWDKKEIVKLGLS---LGVDYTKTYSCYRGGE-KHCNTCPTCIESNESF---------------------
>UniRef50_Q12C85(32-254:282) ExsB n=1 Tax=Polaromonas sp. JS666 RepID=Q12C85_POLSJ   E=1e-32 s/c=0.64 id=22% cov=96%
--KAIVVFSGGPDSLAAALWAKSKKYDPWLLTFQFKQREQgGEMFASMLLAKTLGFPQEIIDFKSPMHSF---EPTVHVLMHAGTTTTADRAQHHRMEFGAGMVMATACTFAVYHQIDDVVWGATKDDVfGGRFEYSQEFADAFANLVSCTTGRPFRIHVPFASKSKHQVLAEFSGKEDL---FAMSWSC-KVGSSIQCGTCTACVARRVAAQASGVKDATSYHEQNYKSPL-
>UniRef50_Q13AQ3(3-204:206) ExsB n=6 Tax=Proteobacteria RepID=Q13AQ3_RHOPS   E=4e-30 s/c=0.66 id=23% cov=87%
---ALLLCSGGLDSTTVGYWLVEKNISFQPLFFDYGQHCvEKEWETLQEV---LPISGLVSPLLRINISEIFQHSPSRLIAEPNLWTEHVEDDDLYIPYRTLMFFSVGACIAQTRGLDAVYAGFINSNHAKELDCSAAFLNNLDSLSR--SLGPVRFELPFRDWSKADVVRRA---NELRVPVGKTYSC-QLFSDTPCGACPNCVERISAIESF------------------
>UniRef50_A4YH21(2-196:199) ExsB family protein n=1 Tax=Metallosphaera sedula DSM 5348 RepID=A4YH21_METS5  E=2e-28 s/c=0.65 id=26% cov=84%
--KSLFLVSGGLDSTAGMYRFREMDYD--CMTIDYGQRAFKEqVKYARINCEKLGKRLIEVNMKKVGDRF---------------REGKSLIPHEPIRHRNAVTIPFALTYASEMGYSAVYVFTVSEEC-QYESNKPEIISALRKL---AEALRIGLIFPFLGLSKAHVLRMGIEHG---MDPLNTYSCLLGHRA-HCGRCSQCESRKMAFKIAGVDDKTKY----------
>UniRef50_C3NEW9(3-191:244) ExsB family protein n=5 Tax=Sulfolobus RepID=C3NEW9_SULIY   E=7e-28 s/c=0.67 id=19% cov=81%
---AIIQLTGGIDSTVLAYYLKDK-YVLHGTFIYYGYPPQiRELELVKELSKKLDVPLKIIDFSSYIKSF----------DLPPIDSIQYIIKYQFV-------IEILASFSAYPNLNTMFVGWLKDE----WSNKMSILKGIESLM------GFKVMAPFHTMVKSEVIKLG---NELGVDFTKTHSCIVSGK-MHCGICMPCRSRRRAFEEAKVKDPTIY----------
>UniRef50_B0V938(149-366:442) Putative uncharacterized protein n=4 Tax=Acinetobacter baumannii RepID=B0V938_ACIBY  E=1e-26 s/c=0.56 id=18% cov=85%
--DSVCLFSGGLDSTIGAIDLKAQGKKSVLVSHAYPKDRQKQ--------------DHVYYDLQFDNARFQV--------LANPRKVKEIPADVQMRTRSFNFIAFGALIATALSKNHfsnkiikLYIPENGlisinppltprrIGALSTRTTHPYFLQKLNILFK-NIGLPVEIENPYQYKTKGEMMLECKDQSSLKKIAATTVSCGKWKRsGMQCGKCLPCLIRRASFDKYQYKDLTQY----------
>UniRef50_B8JF98(142-359:447) PP-loop superfamily ATPase-like protein n=1 Tax=Anaeromyxobacter dehalogenans 2CP-1 RepID=B8JF98_ANAD2  E=7e-25 s/c=0.53 id=23% cov=85%
----VGLFSGGLDSIVGTYLRSRTAKKLIVVSVHGIQvRASAQQRAITMLqrASFFSVPLHWVSFDHQLRH--------------------AHPPEKSQRCRGFLFLSIGAAVARTVGASTLHTYENGIGALNPPMNlaqvgaqntramHPGTLASLEGILEVVQDDPVRLEAPFLFSTKGEMCRDAREH--LIPLAQASNSCDEGEHGKpdpaeHCGLCTSCLLRRSAlFAALGDKDPTPY----------
>UniRef50_B9LWH7(1-189:195) ExsB family protein n=1 Tax=Halorubrum lacusprofundi ATCC 49239 RepID=B9LWH7_HALLT  E=2e-24 s/c=0.61 id=25% cov=82%
MPESVLLLSGGLDSATLAYTHRPD----LTVTVDYGQcCADAEIQASAQIADQLNLE-HEVIEVD--------CENLGAGTMAGQQETDLGDAPEWWPYRNQLVVTLVAMKVVRRGADRLLVGAVADDQS-HADGEAEFFELMDSLLSF-QEGDLGVVAPAIDRTTEEFV---CEVNPPESLLGWTHSC--TASNTACGECRSCKKRQR-----------------------
>UniRef50_B5XVJ1(139-350:421) Putative uncharacterized protein n=1 Tax=Klebsiella pneumoniae 342 RepID=B5XVJ1_KLEP3  E=3e-24 s/c=0.54 id=17% cov=83%
----ISLLSGGLDSLIGGIDLVAKGRKPLFVS----QLAHKDSERQRAYASMLmGNGSHYQWSHGISF---------------------KGSREPSTRGRSLAFYAFALLASTKINLpkPTIFIPENGVISINPPlvpgrvsslstrTTHPMFIDMLQRVLD-NLGIHVQLELPYRFKTKGEMMRECLDQDLLQKWAADSTSCgrFRTYNRQHCGRCVPCLIRRAAFIAWKPEgDTTSY----------
>UniRef50_C7X359(140-371:427) Putative uncharacterized protein n=1 Tax=Enterococcus faecalis Merz96 RepID=C7X359_ENTFA  E=1e-23 s/c=0.48 id=17% cov=89%
----VCMFSGGLDSFIGSIDILRGQTTSNTLFVsHYGGGSKGTKGYQDLLVKEM------INHFSSLSLSNFFSFYSAAMKTPTGQDEPTTRS------RSFMFF--AHAIALTPDNAKLIIPENGfvslniplyfsrNGSSSTRTTHPFYMNLFQKILNI-LGINVRLENPYQFLTKGQMMNNCLDKEFLSRNIINTMSCSHPEQARwsgcsdpiHCGYCIPCTIRRASINEFCSPDPTLYRYL-------
>UniRef50_Q9UWQ2(167-329:363) Putative thiamin biosynthesis protein thiI n=1 Tax=Pyrococcus furiosus RepID=Q9UWQ2_PYRFU  E=4e-23 s/c=0.67 id=21% cov=71%
--KVVALISGGIDSPVAAFLMLKRGAEVIALHFDQGTNAKKVVEKVVEILSDYSPEPIELIVENHFEILK-----------PYVSVLAKLQKREWTCiLCKIAMLKRAAEIAKEEGALGIVTGDSLGQVAS---------QTLSNLFIETISVDYPIYRPLIGFDKEEIVSIAKRIGTYDAFLEY-----------------------------------------------
>UniRef50_O27720(179-338:389) Probable tRNA sulfurtransferase n=5 Tax=Methanobacteriaceae RepID=THII_METTH  E=4e-21 s/c=0.64 id=21% cov=68%
--KVVALLSGGIDSPVATYLMMKRGCQVVAVHMDNAPFTGEEAeEKVEKIAAKL-------AEYSAGVEFKLRTFSYGRYLESCRRGAPEKM--TCVLC-KFGMYHLAEMVAEEEGALAIVDGSSLGQVAS---------QTLPNILATRMGVNIPILSPLIGMDKVEIENLAKRIG-------------------------------------------------------
>UniRef50_O29382(167-324:374) Probable tRNA sulfurtransferase n=2 Tax=Archaeoglobaceae RepID=THII_ARCFU  E=2e-20 s/c=0.65 id=24% cov=65%
--KVVALISGGIDSPVAAFMAMKRGCEVVAVHFFNQTMHSpKVREKIRMLAEKLAEYQGKIKLYMVPFK-----------EVQFEIINRVPPKLRMVVYRRSMM-RMANLIAEKEGCKAVVTGDSLSQVAS---------QTLDNINVIYSASKLAVLPPLIGMDKEEIVAIAK----------------------------------------------------------
>UniRef50_Q2FLN6(172-339:387) Thiamine biosynthesis protein n=1 Tax=Methanospirillum hungatei JF-1 RepID=Q2FLN6_METHJ  E=3e-20 s/c=0.60 id=23% cov=68%
--KAVALISAGIDSPVAAWLMMRRGVRMIFLHIEPGKFGGEDIR--RNLENNLAALSHWVPGLELP------VITIPAEPFYQALMTLSEPKLRCVLCKRG-MLELASRYAQKSGCDGIITGDNLGQVA---------TQTLHNLAPISAGIEIPIYRPLIGYDKEEIITLARKIG-------------------------------------------------------
>UniRef50_B4U7S9(2-190:196) ExsB family protein n=1 Tax=Hydrogenobaculum sp. Y04AAS1 RepID=B4U7S9_HYDS0  E=4e-20 s/c=0.53 id=21% cov=80%
--KVVSLVSSGFDSISLLNYYINKNYEIYPIYVKSGFKWeEEELKHLKDIIDHISksyklIKPLKVSHAPNDFFEDFNERAFINDE------------DVEIPFRNLDLLISALKYAYAVDANLIAIGIMG--LVAFKDNSYNFIKTINDLF--SMYGDYKVDTPFLGMSKKDVFDRY----FIKELFDKAFCCMNPTDGKECGVCSKCKE--------------------------
>UniRef50_UPI00017F5D79(157-385:487) hypothetical protein CdifA_02378 n=1 Tax=Clostridium difficile ATCC 43255 RepID=UPI00017F5D79  E=4e-20 s/c=0.44 id=18% cov=88%
----VSLFSGGLDSFCGALRLLENNKKVFFVTCMEHKLLKKRVNDIYRRVDR---------GYPKLNKNIYVFSANPKRPMNVSKELLNKFSEDTSRSRSFLFMAVAIAVVSIINPKEgVYIPENGfiginlpltksrLGSCSTRTTHVWALKRLNEILTL-LDINIPITNFYKYNTKGEIVDEFKNNKIFKECVKLTLSCSHPTHGRmagatppiNCGYCYPCMIRRASLYKIGFDD--------------
>UniRef50_A8L9C0(132-315:372) ExsB family protein n=2 Tax=Actinomycetales RepID=A8L9C0_FRASN   E=1e-19 s/c=0.54 id=22% cov=74%
----VLLFSAGLDSFPAWHYL----GKPPALYFDLGHRYRDqERAAITALVDRCGIKVTVSQELDLSQWEADDAI---------------------IPLRNVYLAMLAANRAERIWCVGVKGDATA-------DKSPQAFHQISQMITDLSGRPVWLDSPFWQMTKTEIVAWYLGQGLPAGDLLLTFSCSRTDSAmTHCGQCPSCLRR-------------------------
>UniRef50_Q47DY3(149-377:457) Putative uncharacterized protein n=5 Tax=Proteobacteria RepID=Q47DY3_DECAR  E=6e-19 s/c=0.42 id=19% cov=84%
--DAVSLFSGGLDSLIGAIDLLEAGRTPLLVS-HAGEGATSDAQNV-LFAA---LKKHF---SAVAFDRLRVWMLFPADLVQGVSSENSTR------GRSFLFFALGVFAGTGLGTDFVLRvpenGLIALNVPldplrlgsnSTRTTHPYYIARWNDLLGH-LGISGRVENPYWAKTKGEMASACANPVLLKALAPYALSCAHAANARHlgikgrgieqCGYCLPCLIRRAALD--------------------
>UniRef50_Q9V1S6(2-161:198) ThiI thiamin biosynthesis protein thiI n=3 Tax=Pyrococcus RepID=Q9V1S6_PYRAB  E=1e-18 s/c=0.60 id=22% cov=68%
--KVVALLSSGIDSPVAIHLVASKGAEVYPLHFK--QDDVKE-NKVRRIVKRLQEIHgDKVKDPRIVDAF--------EVQGPVFEKLREIRKEKWTCiFCKYTMYIVATSYAREIKAKAIVTGDSLGQVAS---------QTLDNLMVMSTATELPILRPLIALDKEEIVRIAKEIGTFD----------------------------------------------------
>UniRef50_B7H703(180-337:404) Probable tRNA sulfurtransferase n=75 Tax=Bacteria RepID=THII_BACC4   E=1e-18 s/c=0.60 id=19% cov=65%
--KVMVLLSGGIDSPVAAYLTMKRGVSVEAVHFHSpPFTSERAKQKVIDLAQELtkyckRVTLHLVPFTEVQKTINKEIPSSYSMTVMRRMMMR-----------------ITERIAEERNALAITTGESLGQVAS---------QTLDSMHTINEVTNYPVIRPLITMDKLEIIKIAEEIG-------------------------------------------------------
>UniRef50_Q042N0(179-339:405) Probable tRNA sulfurtransferase n=144 Tax=Bacilli RepID=THII_LACGA   E=2e-18 s/c=0.59 id=21% cov=70%
--RAVMMLSGGIDSPVASYLAMKRGVEIDMVHFFSpPYTTEKALAKAKELT---GILANYSGKINFIAVPFTEIQEQIKEKLPEGYLMTIQRR---------FMLQLADRIRAKRGGLAIFNGESVGQVAS---------QTLESMVAINDVTSTPVLRPVATMDKTEIIKLAEQIGTFDLSIE------------------------------------------------
>UniRef50_Q65G52(179-336:401) Probable tRNA sulfurtransferase n=20 Tax=Bacillales RepID=THII_BACLD  E=2e-18 s/c=0.60 id=22% cov=64%
--KAMLMISGGIDSPVAGFYAMKRGLEIEAVHFFSpPYTSERAKQKVIDLTKRLtafggDIKLHIV------------PFTKTQELIQKQIPENYSMTAT-----RRLMLQIADKLRERHNALAIFTGESLGQVAS---------QTLESMYAINAVTSTPVLRPLIGMDKTEIIEKAKE---------------------------------------------------------
>UniRef50_Q8TWX3(167-329:374) ATP pyrophosphatase involved in thiamine biosynthesis n=1 Tax=Methanopyrus kandleri RepID=Q8TWX3_METKA  E=2e-18 s/c=0.58 id=20% cov=71%
--RVVCLVSGGIDSPVAAWYAARRGCEVIWLHLDRG-KYGSEVDAVERLAGKFS---------EWLPSDVELLIEDFEDFMESLEGLEGESARYRCVLCKREMIRRACDVCENVGAVAVVMGDVIGQVASQIPDNLAVIDRVAR---------FPVFRPLLGFDKNEVQRLSERLGLFEVSKEH-----------------------------------------------
>UniRef50_Q17440(1-225:375) Probable mitochondrial tRNA-specific 2-thiouridylase 1 n=2 Tax=Chromadorea RepID=MTU1_CAEEL  E=8e-18 s/c=0.41 id=18% cov=73%
MPRVVIGMSGGVDSAVSAFLLKKRGFDVIGLHMinwdvqeegTSHCPRSKDESDARNVCDRLNIPFHTVNFVKEYWNDVFLKFLENYKNGRTTVPDIDCNQS--------IKFDVFHKIArEKFNADFIATGHYATTNFGDFQQNAKDSDEIrlfsgkdplkDQTFFLCTVNQEQLkraMFPLGSLQKSEVKRIAEEQG-------------------------------------------------------
>UniRef50_Q9Y933(221-386:512) GMP synthase [glutamine-hydrolyzing] n=5 Tax=Archaea RepID=GUAA_AERPE  E=1e-17 s/c=0.56 id=22% cov=71%
---AVAAVSGGVDSTVAALIAKKAiGSRLYPVFIDHGLHPEGEVERVVKLLSRLGLEPVMVDAGEEF--------------LAALEGVGDPEEKRRVVGR--VYAEVLERAARDIGAEYLVQGTIYPDVIESGARPgADTIKTHHNVGGLPKDMRLKLVEPLRYFYKDEVRLLAEK---LGVPRELIW---------------------------------------------
>UniRef50_C4FTQ9(180-337:404) Putative uncharacterized protein n=1 Tax=Catonella morbi ATCC 51271 RepID=C4FTQ9_9FIRM  E=4e-17 s/c=0.57 id=19% cov=67%
--RALLMLSGGIDSPVAGYQMMKRGLEIEAVHFASPPYTSPQaIEKTKKLTAQL---------AQYGRSLTYHCVPFTEIQEEIKDKVHDDFSMTIMR---RMMLRVMEALLDRQQADAIVTGESLGQVAS---------QTLKSMRAINQVTSVPILRPLIAVDKNDIIVQAEAIG-------------------------------------------------------
>UniRef50_D0Y5H1(169-381:638) Putative uncharacterized protein n=1 Tax=Dehalococcoides sp. GT RepID=D0Y5H1_9CHLR  E=2e-16 s/c=0.41 id=17% cov=81%
----VMLFSGGLDSLAGAVELLEDSKDVICL--VSHQSQPGTVKTQNGLFKAL---------KDAYSDRVRHYQFKCSLVSTVNRAVEETQRT-----RAFLYTSIAYAIASSQRNPRFYVHENGVtslnfarrqdgiNARTSRTTHPRTLSLLQDFFSLVHGSKVQVATPFLFKTKSDIFRELSAHKR-ENLIPSAVSCSKTFlnrkQASHCGGCFQCIDRR------------------------
>UniRef50_D0MFG9(186-339:500) Thiamine biosynthesis/tRNA modification protein ThiI n=1 Tax=Rhodothermus marinus DSM 4252 RepID=D0MFG9_RHOM4  E=9e-16 s/c=0.56 id=21% cov=67%
---ALVLISGGFDSAVAAWLAMRRGVSVDYLFCNLGGKAYE--RAVLQVAKVL-------ADAWSFGTRPRFYSVDFGPVVDEMRRHVRPAYWQVVLKR--LMYRAGEAVARRTEALALITGESLGQVSS---------QTLKNLQAIEAGTSLPVLRPLLTYDKEEIINLARKIG-------------------------------------------------------
>UniRef50_Q9HM45(158-369:477) Putative uncharacterized protein Ta0024 n=2 Tax=Thermoplasma RepID=Q9HM45_THEAC  E=3e-15 s/c=0.40 id=21% cov=86%
--RVAVMSSGGKESLTTFGMLREIGADVFPVFFNESGGHWKTAKIAYDYMKKNYSNVHKVWSNVDRFYSFMNGHM-PMLDQKEIRKTADSYPVQMFIFPVYVFSML--PYVIKYGIGNIALGDEFDDpiyqekyrgikhFYGVYDQTNEFNDTVSDLLAR-IGMPVRVFSAVypIFGTLVEKILVKRYPELLRIQRSCHLCHYEGEEVVPCGRCTKC----------------------------
>UniRef50_A3CVZ2(177-335:392) Thiamine biosynthesis/tRNA modification protein ThiI n=1 Tax=Methanoculleus marisnigri JR1 RepID=A3CVZ2_METMJ  E=1e-14 s/c=0.52 id=18% cov=68%
---VMALLSEGIDSPVASWLMMRRGCLVVHVNMHGGRFGGAD-------AEKNVLANHARLSLWVPGHALDLLVVEMEPFFTAITGLKEPRYRCVLCKR--FMLRVASLLATERGAAALVSGDNLGQVAS---------QTLANMAVIAPAATVPVLRPLIGFDKEEVVDRARAIG-------------------------------------------------------
>UniRef50_D1PL47(12-212:348) tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase n=1 Tax=Subdoligranulum variabile DSM 15176 RepID=D1PL47_9FIRM  E=1e-14 s/c=0.41 id=22% cov=26%
--KVLMGMSGGVDSSVAVRILQEQGFAVQGAVIRFSPAHDGAVSAAQESAKTLQIPLHII---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B5CVE8(7-190:233) Putative uncharacterized protein n=1 Tax=Bacteroides plebeius DSM 17135 RepID=B5CVE8_9BACE  E=2e-14 s/c=0.44 id=20% cov=71%
-EKKVLLYSGGMDS-----WLIDKIWKPDVkLYVDMGTKYSQE--EIKRL--------------------------PADVVVEKLDLSKWEREDKIIPLRNMYLIGIATNYG-----NEICLGATAGD--RVLDKSPVFADIYEQLLNYLyqkqhwtEERKIKINLDFKRYTKAELVRAFiAQGGDMDEAFSSSFSCYTPEHGKECWSCKPC----------------------------
>UniRef50_B0TD47(152-375:453) Putative uncharacterized protein n=1 Tax=Heliobacterium modesticaldum Ice1 RepID=B0TD47_HELMI  E=2e-14 s/c=0.36 id=21% cov=84%
----VSLFSGGMDSLIFAINSLEEKKTPLFISHAgdgYTKNYQKEIintlsnNYADISFSQLNLwmsfNKHIVSQSCKENTTRSRSFLYISLALFALSGL-PKVDILDVPENGLI--------AINVPLDDLRVGSHST-----RTTHPYYFKLWNEILGI-VNLGKSIRNPYWNKTKGEMARDCLNKELLLDLLPISMSCsaptkyrYRGSTHMHCGHCVPCIIRRAAIN--------------------
>UniRef50_Q9YEW8(182-337:396) Probable tRNA sulfurtransferase n=1 Tax=Aeropyrum pernix RepID=THII_AERPE  E=3e-14 s/c=0.52 id=20% cov=66%
----LALYSGGFDSGVAAWMIMRRGSPVHLAFYDFGVPEA--LEVAVEGAKTLAGEW-------AWGYRPRLYVVNFRGAALIVNGLVKPSYRTLVLRR--LMLLHAQDLAAREGFEALVTGESVGQVAS---------QTVRNLRLISSGLELPVLRPLAGMDKDEIVEKSREIG-------------------------------------------------------
>UniRef50_B8D0L5(192-348:396) Probable tRNA sulfurtransferase n=4 Tax=Clostridia RepID=THII_HALOH   E=1e-13 s/c=0.50 id=16% cov=63%
-----------IDSPVAGWLAMKRGIELEALYFHsFPYTSDRAKEKVIDLTKVLSRYCKKIKLYVGYFT-----------DIQRAIQENCPQKYYITIMRR-MMYRMAERIARKNGDLVLITGESVGQVAS---------QTLESMNVINEVTNMPVLRPLATMNKTEIMDLAREIG-------------------------------------------------------
>UniRef50_Q12W34(18-177:267) ATPase of the PP-loop superfamily n=1 Tax=Methanococcoides burtonii DSM 6242 RepID=Q12W34_METBU  E=4e-13 s/c=0.48 id=27% cov=68%
-EKVLVAFSGGVDSSTlAALAFAALGDNALAVTLYSPMIPQSELEYAKRTAEVIGIK-HIVLDHDILSDER----IRINDPQRCYYCKKQ-------------FVKKLKGVASEEGLNVIMEGTNASEI----TGRRPGLEALREAGS-------SIFTPYVDFDvsKREVRQMASYLG-LDVANRPSNSC-------------------------------------------
>UniRef50_A8AAD7(47-161:383) PP-loop domain protein n=1 Tax=Ignicoccus hospitalis KIN4/I RepID=A8AAD7_IGNH4  E=5e-13 s/c=0.67 id=30% cov=26%
-KRVLLGLSGGKDSVALLYLLKKVGTEVVAATVDTvPNYTSLEAELAKRVAEELGVTHYTV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B8I986(35-198:329) Putative uncharacterized protein n=1 Tax=Clostridium cellulolyticum H10 RepID=B8I986_CLOCE  E=3e-12 s/c=0.46 id=30% cov=24%
-----VLFSGGKDSTYLANIMKQmKGGRVCTLTVDNGFEDEVFLDHVKKVADKIGVDSYII---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1CE79(18-177:417) Argininosuccinate synthase n=2 Tax=Bacteria RepID=D1CE79_THET1   E=4e-12 s/c=0.46 id=31% cov=26%
-RKVALAYSGGLDSALCLVLLREKYgaEEIIPITVDVGQ-GQDEVEQSFKKAEVLGVEPLLI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C1E3H1(296-472:780) Predicted protein n=1 Tax=Micromonas sp. RCC299 RepID=C1E3H1_9CHLO   E=7e-12 s/c=0.41 id=23% cov=24%
-RSVAISLSGGVDSMVLATILKAAapsfgDFDVVAMHIDYANRPEsgKEADFVRGWCERKGIV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q6WHP6(7-175:228) Putative uncharacterized protein n=1 Tax=Vibrio phage KVP40 RepID=Q6WHP6_BPKV4  E=9e-12 s/c=0.43 id=23% cov=73%
----IILVS-GLDSLV-LYEFLER--KPHPVYFKWGF-AIDDIEMAAL------PEETTIIEMPEILHLKHDP------------YEFKTPRNPDLIGRNTLMF---NSVFHAFRPNVIYRGMLKGDDF-YYDASPTHSDEIAAMWSKMLNKECRIEQPFKDKTKRDIMQMAVEYGIDANSLQH---CYN--REHNCGRCSKCV---------------------------
>UniRef50_B3EEY5(9-218:250) Putative uncharacterized protein n=1 Tax=Chlorobium limicola DSM 245 RepID=B3EEY5_CHLL2  E=1e-11 s/c=0.34 id=18% cov=83%
-----LLWTGGWDSTYRLCELTRNGKTVQPFYIlDSTRKSIRHELAAMDTIK--------VALKQKYTEGSAKILPTIYINQSDIIIDQETSTQYKNLSRKYHIGKQFEWLSAYVKANGLSGMEIAIEKNNFRQRDHFFYYLGKHLISTNNTITLSYEstdqdlllfkgfsFPIYNTTKIAMLAEAKKYN-YETILALTWFCHNPIRNKPCGMCNPCK---------------------------
>UniRef50_Q83CD9(191-339:392) Probable tRNA sulfurtransferase n=5 Tax=Coxiella burnetii RepID=THII_COXBU  E=6e-11 s/c=0.47 id=16% cov=63%
-----------IDSPVAGWTLLKRGMMIDAVYFHsFPYTGEKAKEKVIDLAR--------VLTSWKLRAINLHIPYFTKIQ---ETVNKMCPESTWTIIHRRFMMRIAEKLTKST-YHTLITGENLGQVAS---------QTIQNIAVINQATNLPILRPLISFDKNDIIKIAEKIG-------------------------------------------------------
>UniRef50_B3T2X9(19-174:268) Putative tRNA methyl transferase n=3 Tax=environmental samples RepID=B3T2X9_9ARCH  E=9e-11 s/c=0.44 id=29% cov=26%
---VLVALSGGVDSALVAYSAyAKLGKSAISVTADYKTLAQEELEYAKKISLEIGIK-HIVIE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q5NLX8(31-189:329) tRNA(Ile)-lysidine synthase n=3 Tax=Zymomonas mobilis RepID=TILS_ZYMMO  E=1e-10 s/c=0.44 id=26% cov=23%
-------VSGGSDSLALLLLGAVSDFPVEAVTVDHGMRPEaaEEARFVAQICQQIGVPHQIL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C6HVS1(1-191:372) tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase n=1 Tax=Leptospirillum ferrodiazotrophum RepID=C6HVS1_9BACT  E=1e-10 s/c=0.36 id=22% cov=69%
MKRnksIVIGMSGGVDSAVSAWLLKKEGYDVTGVILRLWGKDSSEASKgwgertcchvpmVEYLCQKiLNIPYAIVDAESAFKsdvvDSFKSAYRTGETPNPCTSCNEK------------VKLPLLRRWAEENGIPKVATG-----HYTYWKRSEDFnVSGLAMAHDLAKDQsyflsrtpdlcPENTVFPVGRMSKPQVRELAREAG-------------------------------------------------------
>UniRef50_C0GTF7(2-139:344) tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase n=1 Tax=Desulfonatronospira thiodismutans ASO3-1 RepID=C0GTF7_9DELT  E=1e-10 s/c=0.50 id=25% cov=25%
--RIAVAVSGGLDSLASLVMLREEGHDVLALHARFFPRLDEHLEKrLKGICTSLGVEMH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6UTF4(28-195:279) ExsB family protein n=1 Tax=Methanococcus aeolicus Nankai-3 RepID=A6UTF4_META3  E=3e-10 s/c=0.40 id=20% cov=72%
-KTVIISYSGGADSLLVAKIASNAAKEHLAITIDNGFFTKQAIINSKIRAKKYNIN-HKIINIDYFNSEFNNKNNNIDI---NIENINNDLKNRCYYCKKDIALTIKGQL-KKYDYDMIVDGTNYSDLFEDRPGIKAYKEQ-------------NIKSPLaeLHITKKEVFKL-LDYLDMELPKKD--SC-------------------------------------------
>UniRef50_D2R5W3(37-179:291) ExsB family protein n=3 Tax=Planctomycetaceae RepID=D2R5W3_9PLAN   E=2e-09 s/c=0.45 id=30% cov=28%
---VAVAFSGGVDSAVVAKAAQlSLGDAAVAVTGVSPSLASGELEIAIEVASAIGIR-HEIMRTDELG--------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B8FFA6(29-176:279) ExsB family protein n=1 Tax=Desulfatibacillum alkenivorans AK-01 RepID=B8FFA6_DESAA  E=2e-09 s/c=0.44 id=28% cov=26%
-KSVLVAFSGGVDSSlLLALAQQALGDKTAAGTVDSPLLPQREKQEAALLTQQLGIKHHII---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B6YQY9(1-121:400) Argininosuccinate synthase n=31 Tax=Bacteroidetes RepID=B6YQY9_AZOPC  E=3e-09 s/c=0.53 id=29% cov=26%
MKrKVVLAYSGGLDtSFCVMYLSQELGYEVYTALANTGGFTEEDLKKVEKRAYKLGAKKH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C9RPN2(219-405:611) GMP synthase, small subunit n=1 Tax=Fibrobacter succinogenes subsp. succinogenes S85 RepID=C9RPN2_FIBSS  E=4e-09 s/c=0.34 id=17% cov=76%
-RKVFLLVSGGVDSTVAFVLLNRvLGPEkVLGLHVDNGMMRLGESQKIMDFLTKEGMNNLKIRDASKHFLAKLKGVTAPETKRGIIGKEFLTVKDEEMAKLNLD----PNEWMMAQG--TIYPDTIESGGTKNADKIKTHHNRVQEVLDLMEKGL--VLEPLADLYKDEVRALGE---ELGIPHNLVW---------------------------------------------
>UniRef50_B1L682(49-172:328) tRNA(Ile)-lysidine synthase MesJ n=1 Tax=Candidatus Korarchaeum cryptofilum OPF8 RepID=B1L682_KORCO  E=5e-09 s/c=0.52 id=37% cov=26%
--KVMVAHSGGKDSSLALLLTKEFSDEvreldlkVISVTLDEGTLYRRsSIELARKLAERLRVRHLTI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B4S4F3(9-213:243) Putative uncharacterized protein n=1 Tax=Prosthecochloris aestuarii DSM 271 RepID=B4S4F3_PROA2  E=5e-09 s/c=0.31 id=16% cov=83%
-----LLWSGGWDSTFrLCDLLLVQDRRVRLYYvVDPGrQSVAQEIKAMQRIRKRL------QERIASFDTRLLSMQVVWLWEIAPESSMTSRYESLRKRFKSFGPqYEWLGRFVAEQGIGDLelsIESNSFRPNGPLWSALEDMLVEEERNFRLCDNPSDPdfeffrsFRFPLIKTTKLAMMHYAKEHG-FDDIMFQSWFCHTPHNGRPCGICHPC----------------------------
>UniRef50_Q2GC97(27-185:326) tRNA(Ile)-lysidine synthase n=1 Tax=Novosphingobium aromaticivorans DSM 12444 RepID=TILS_NOVAD  E=1e-08 s/c=0.39 id=24% cov=65%
--RVCLAVSGGPDSLALMLLMQEVAPRDFCVaTVDHGLRAESAAEAAmvAGLCEMRGIAYHTL-----------------RLDLAGGSAVQE-------RARKARYAALA-DLARRDGLSAVVTAHHADDQAETLVMRLNrgaglrGLAGMRAASSVPGAGEVRLLRPLLGWRRAELVALVEDAG-------------------------------------------------------
>UniRef50_A6DB20(4-147:323) Putative uncharacterized protein n=1 Tax=Caminibacter mediatlanticus TB-2 RepID=A6DB20_9PROT  E=3e-08 s/c=0.42 id=25% cov=22%
----LLAFSGGIDSSALFFWLMEKNIDFDIAIVNYHTRetSDEEVEYAKYLAKKYN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q7MBG3(267-436:606) PUTATIVE ASPARAGINE SYNTHETASE (GLUTAMINE-HYDROLYZ) n=1 Tax=Wolinella succinogenes RepID=Q7MBG3_WOLSU  E=4e-08 s/c=0.36 id=30% cov=23%
-------LSGGLDSSGVAALASQQydfGEKLVAIHAKSSLKESDESSYAIEVANHLGLDLHMV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1UGP9(238-363:460) Putative uncharacterized protein n=1 Tax=Burkholderia sp. CCGE1001 RepID=D1UGP9_9BURK  E=8e-08 s/c=0.47 id=27% cov=32%
-------------------------------------------------------------------------------------------------------------------------------------CYPGFTKQLSRFLEKLTRKSIDFYHPALFQTKAQVlMQLEGHGVGLGQVLAQHWSCsydsrwaHAEHRKVHCGICGNCLLRR------------------------
>UniRef50_Q9YA52(50-175:331) Putative uncharacterized protein n=1 Tax=Aeropyrum pernix RepID=Q9YA52_AERPE  E=9e-08 s/c=0.47 id=23% cov=50%
--RVLAAVSGGKDSSTLLAVLSRLsrriGFHVVALYIHLGIYEYSEksREASIRLASQLDV-PLIVFDLNEVLGAGIPELAKASKRPPC---SVCGMVKRYVIN----------AAAVELGVDAVALGHNADDIAVY----------------------------------------------------------------------------------------------------
>UniRef50_C1TM92(80-236:510) tRNA(Ile)-lysidine synthetase n=1 Tax=Dethiosulfovibrio peptidovorans DSM 11002 RepID=C1TM92_9BACT  E=1e-07 s/c=0.38 id=24% cov=46%
-KRIAVAVSGGSDSMALLWLMLNCWPnDISVIHVEHGIRgdsSKADACFVKEHCKKLDIPCFIL-----------------SRDVPVEAMKGESLEQAARRIRHEAL----ASKAEEIGSDFVALGHNSDD--------------------------------------------------------------------------------------------------------
>UniRef50_C1E3Q0(237-411:662) Asparagine synthase n=5 Tax=cellular organisms RepID=C1E3Q0_9CHLO   E=1e-07 s/c=0.34 id=30% cov=24%
-----VLLSGGLDSSLITSIAVRHKKESkntfgadEPVHsFSIGIKGAPDLIAARKVADALGTVHHEI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q60377(256-311:480) Uncharacterized protein MJ0066 n=5 Tax=Methanocaldococcus RepID=Y066_METJA  E=1e-07 s/c=1.06 id=23% cov=24%
-KPVMVAFSGGKDSLVTLILtLKALGKDIDVVFIDTGLEFEETLKNVEDVERHYGIK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B3RJD9(19-176:462) Putative uncharacterized protein n=1 Tax=Trichoplax adhaerens RepID=B3RJD9_TRIAD  E=2e-07 s/c=0.37 id=30% cov=23%
-------VSGGVDSISLCVLARQYFQKLFAITVDHRLRAESsqEAQNVNEILDKLNIPHKIV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q1VVM8(223-392:524) Asparagine synthetase B n=1 Tax=Psychroflexus torquis ATCC 700755 RepID=Q1VVM8_9FLAO  E=2e-07 s/c=0.34 id=24% cov=24%
-----CLLSGGLDSSLVAGIlarkLKEKGKQLE--TFSIGLEGSPDIVAAKIVADHIGSIHHSIV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B8D4L7(51-219:321) ATPase, PP-loop superfamily n=1 Tax=Desulfurococcus kamchatkensis 1221n RepID=B8D4L7_DESK1  E=2e-07 s/c=0.35 id=31% cov=25%
---VVIAVSGGKDSmsllTVLVKQARELGiREVIGLHLNLGIGGFSELVEsvVREYCERLGVKCHVI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q2FTJ5(2-146:197) PP-loop n=2 Tax=Methanomicrobiales RepID=Q2FTJ5_METHJ   E=2e-07 s/c=0.40 id=36% cov=24%
--RAAVLFSGGKDSSLAAILL-STWYEVELNTYLFSQDTN--IDAVRKAAGSLGFPHHI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B0S1S2(24-178:241) NH(3)-dependent NAD(+) synthetase n=4 Tax=Clostridiales Family XI. Incertae Sedis RepID=NADE_FINM2  E=4e-07 s/c=0.37 id=21% cov=67%
-KGAVFGISGGIDSAVLACLCKKAfGDNALGLIMPIKSNPKDE-EDARILAKSIGLRFTKVDLNESYDALIGTFEKNSVEMAASNIKPRLRMITLYY-------------YAQNNGYMVL-----------SGSNRSEFMTGYFTKYGDSGAD----LMPLLNLYKTDIFEMAKVLGVPDVIINK-----------------------------------------------
>UniRef50_Q0C5V2(27-90:367) tRNA(Ile)-lysidine synthase n=1 Tax=Hyphomonas neptunium ATCC 15444 RepID=TILS_HYPNA  E=4e-07 s/c=0.90 id=29% cov=23%
-----VAVSGGSDSLALLIlahrWAARRGRVLRALTVDHGLRPESraEAEAVGRLCADMGIE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C5EFL1(28-126:514) Hypoxanthine phosphoribosyltransferase n=1 Tax=Clostridiales bacterium 1_7_47FAA RepID=C5EFL1_9FIRM  E=5e-07 s/c=0.58 id=25% cov=26%
--RVIAAVSGGADSVCLLTLLcgmkKDWDLKLMAVHVHHglrGQEADRDADFVRALCEELEVTCHII---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6Q5J5(224-285:571) Putative uncharacterized protein n=1 Tax=Nitratiruptor sp. SB155-2 RepID=A6Q5J5_NITSB  E=6e-07 s/c=0.91 id=23% cov=24%
------LLSGGVDSSFVSAAAKEMQGYLATYSIGYEEKRYSELRYARMVASHIGSEHTEVV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A1RXY7(233-299:614) Phosphoadenosine phosphosulfate reductase n=1 Tax=Thermofilum pendens Hrk 5 RepID=A1RXY7_THEPD  E=6e-07 s/c=0.84 id=27% cov=23%
-----VSLSGGKDSLVTLHLAVKAlgNEKVKALFNNTGLEFEETVEYARRIADYYGVE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D2V0C9(277-332:588) Asparagine synthetase n=1 Tax=Naegleria gruberi RepID=D2V0C9_NAEGR   E=7e-07 s/c=1.01 id=25% cov=24%
-----VFLSGGLDSSLVAALVKKytNQPRLHSFSIGIGANESSDLVAARKVAAHLGTVHHE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q30PR9(13-160:329) tRNA(Ile)-lysidine synthetase-like protein n=1 Tax=Sulfurimonas denitrificans DSM 1251 RepID=Q30PR9_SULDN  E=8e-07 s/c=0.38 id=29% cov=26%
-KKNLLAFSGGADSSALFFLLTQESIPFDIAIVNYGIReqSRDEVAYAKELSAANNITCHI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A8RIZ7(23-87:479) Putative uncharacterized protein n=1 Tax=Clostridium bolteae ATCC BAA-613 RepID=A8RIZ7_9CLOT  E=9e-07 s/c=0.86 id=24% cov=26%
--RVIAAVSGGADSVCLLALLCAwrepRGISIRALHVHHGLRgeeADRDADFVRSLCEGLHVPCHIL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1RLT0(21-76:460) tRNA(Ile)-lysidine synthase n=1 Tax=Legionella longbeachae D-4968 RepID=D1RLT0_LEGLO  E=9e-07 s/c=1.00 id=31% cov=23%
----IVGFSGGLDSTVLLHALAAHpilLDKIVAVHVNHGINANADFwqEHCKQFCQKLGV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q5L3T3(21-184:464) tRNA(Ile)-lysidine synthase n=9 Tax=Bacillaceae RepID=TILS_GEOKA   E=9e-07 s/c=0.34 id=29% cov=21%
---VIVGVSGGPDSLALLHVFLSLRDEwklqVIAAHVDHmfrGRESEEEMEFVKRFC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q4BY27(312-455:542) Asparagine synthase (Glutamine-hydrolyzing) n=1 Tax=Crocosphaera watsonii WH 8501 RepID=Q4BY27_CROWT  E=1e-06 s/c=0.39 id=25% cov=24%
-----VYLSGGLDSSCVTALAKQfHQETVHTYSIHFGEDYPNELEFSSLVAAHCQTKHHIL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A5UW35(221-363:498) Asparagine synthase (Glutamine-hydrolyzing) n=2 Tax=Roseiflexus RepID=A5UW35_ROSS1  E=1e-06 s/c=0.39 id=32% cov=23%
-----VSLSGGLDSSIIALLACAELDHIE--TFAVGMEGSEDLEAARRMAQYLGTRHYE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C4R8P4(23-201:483) Putative uncharacterized protein n=1 Tax=Pichia pastoris GS115 RepID=C4R8P4_PICPG  E=1e-06 s/c=0.31 id=25% cov=28%
-RRVGISLSGGVDSMALTSLLSRYrdeynvGVEIVALTVNHEYRkgSRQEAEEVGKLVAPLNV-QHKIIDLKW----------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A3CJX7(20-92:425) tRNA(Ile)-lysidine synthase n=38 Tax=Streptococcus RepID=TILS_STRSV  E=2e-06 s/c=0.76 id=25% cov=24%
-RKVLIAVSGGLDSMTLLQLLivsqKELAIELAIAHVNHKQRPESdqEEKALVKIAEQLGVK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A3CSR6(49-168:343) PP-loop domain protein n=1 Tax=Methanoculleus marisnigri JR1 RepID=A3CSR6_METMJ  E=2e-06 s/c=0.46 id=26% cov=23%
---VAVALSGGKDSSAVLFFLHrllgeRRDVRLMAITVDEGISGYRDPNQARKIAESMGV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q1NGU9(239-361:585) Putative uncharacterized protein n=1 Tax=Sphingomonas sp. SKA58 RepID=Q1NGU9_9SPHN  E=2e-06 s/c=0.45 id=33% cov=21%
-------LSGGLDSSIVTAGLSKAGTPFQCVTLVTENRNGDERDYARAMASSVGA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q02CD2(264-405:644) Asparagine synthase (Glutamine-hydrolyzing) n=1 Tax=Candidatus Solibacter usitatus Ellin6076 RepID=Q02CD2_SOLUE  E=2e-06 s/c=0.38 id=25% cov=24%
-------LSGGVDSSAIAALMKRNFSgPVKTFAVGYQEAEFSELSYARHVAGAIGTDHHEVV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C8PFK4(19-169:333) tRNA(Ile)-lysidine synthase (TRNA(Ile)-lysidinesynthetase) n=1 Tax=Campylobacter gracilis RM3268 RepID=C8PFK4_9PROT  E=3e-06 s/c=0.36 id=28% cov=23%
--KNLLAFSHGVDSTALFYLLDEAGVKFDLAIVDYNVRAqsKDEVASARYLAVKFN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q1R016(30-120:430) tRNA(Ile)-lysidine synthetase-like protein n=1 Tax=Chromohalobacter salexigens DSM 3043 RepID=Q1R016_CHRSD  E=4e-06 s/c=0.60 id=33% cov=22%
-----VALSGGLDSSLLLTLAvaacRRHPRPLYAVHVNHGlQDAAADFEAhARWLCGRLGV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B7GFR9(245-341:508) Carboxyethyl-arginine beta-lactam-synthase (Beta-lactam synthetase) n=1 Tax=Anoxybacillus flavithermus WK1 RepID=B7GFR9_ANOFW  E=6e-06 s/c=0.55 id=25% cov=23%
-----VILSGGIDSSAITSLIAPKVTKLY--TFSIGTESANEFEYAKLVADRYQTDHHE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q9YA97(4-125:232) Putative uncharacterized protein n=1 Tax=Aeropyrum pernix RepID=Q9YA97_AERPE  E=6e-06 s/c=0.44 id=28% cov=25%
--KTVVSWSGGKDSSLTIYSLYRMGFDVegVLVTVDSTSKrvtgHRVPLEAVEAQARAAGLELHI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C7PAG8(264-400:633) Asparagine synthase (Glutamine-hydrolyzing) n=1 Tax=Chitinophaga pinensis DSM 2588 RepID=C7PAG8_CHIPD  E=8e-06 s/c=0.39 id=28% cov=22%
-----VFLSGGYDsSSVAAILQASSGSRLKTFTIGYKEAAFDESKEARRIAQHLG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C8WM75(171-307:508) Putative uncharacterized protein n=1 Tax=Eggerthella lenta DSM 2243 RepID=C8WM75_EGGLE  E=9e-06 s/c=0.38 id=21% cov=58%
-RTAVIPITSGLDSRTIAACLKAADYE-RVLTFSIGARDSEDVMIGKRVASNLGFPWEHVEITGEMWRERFAS-----------DRYREALRYSILGGRiNHILMAFALDILKGRGAlpdDAVFLPGHAGSImGGELKCSPVFKRAISKA--------------------------------------------------------------------------------------
>UniRef50_C0VZS9(194-248:538) Putative uncharacterized protein n=1 Tax=Actinomyces coleocanis DSM 15436 RepID=C0VZS9_9ACTO  E=1e-05 s/c=0.96 id=29% cov=23%
----LIPLSGGADSRLLLAVLKELNAENV-LCFTYGQPDSREAQISKSVAEGLGFK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C7H6B5(224-283:524) Asparagine synthase n=4 Tax=Firmicutes RepID=C7H6B5_9FIRM   E=3e-05 s/c=0.85 id=31% cov=23%
------LLSGGLDSSlVCSIAAKKLGKPIR--TFAIGMDTDAiDLKYARQTADYLGSEHHEII--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C9M6N1(24-179:419) tRNA(Ile)-lysidine synthase n=1 Tax=Jonquetella anthropi E3_33 E1 RepID=C9M6N1_9BACT  E=4e-05 s/c=0.32 id=30% cov=22%
-----VAVSGGGDSMGLLWLCLASGLRPcAAIHLDHGLRPSSadERRFVEETCGRLG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q4FTY4(268-410:623) Probable asparagine synthase, glutamine-hydrolyzing n=1 Tax=Psychrobacter arcticus 273-4 RepID=Q4FTY4_PSYA2  E=6e-05 s/c=0.35 id=25% cov=21%
-------LSGGVDSSLVTAILQKYSDiPINTFTIGFEDKNYDESIYAKAIADHLG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C7M1A7(1-143:265) Putative uncharacterized protein n=1 Tax=Acidimicrobium ferrooxidans DSM 10331 RepID=C7M1A7_ACIFD  E=7e-05 s/c=0.35 id=23% cov=61%
----MVLLSGGVDSGVLAVAGTRAiGDQAVAVTGRSASLAADERDAIARLVLENGICHVEVATH----------------EGEDPAYVRNDRMRCYVC--KTHLFRAAGPVAEERRA-VMVTGAHVDDLG---DWRPGMLAAEEA----------GVRAPFLELgvNKASIRSLARELG-------------------------------------------------------
>UniRef50_P64248(279-361:652) Putative asparagine synthetase [glutamine-hydrolyzing] n=69 Tax=Bacteria RepID=ASNH_MYCBO  E=0.0001 s/c=0.59 id=34% cov=22%
-------LSGGIDSTAIAALAIRHNPRLITFTTGFEREGFSEIDVAVASAEAIGAR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A7NNE3(240-367:576) Asparagine synthase (Glutamine-hydrolyzing) n=4 Tax=Bacteria RepID=A7NNE3_ROSCS  E=0.0002 s/c=0.38 id=27% cov=26%
-----VFLSGGIDSSLVTALAARlHDHSVHTYAINFGAEFPNELAYSSLVAAHCGTT-HTVLTFD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C5ZZB9(252-328:563) Asparagine synthase n=3 Tax=Helicobacter RepID=C5ZZB9_9HELI   E=0.0002 s/c=0.62 id=25% cov=21%
--------SGGVDSSILAHLAKRIGVECLYFGINFKETKQNEIQHMKQLQKDLGI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A4RXB8(232-293:543) Predicted protein n=2 Tax=Ostreococcus RepID=A4RXB8_OSTLU   E=0.0003 s/c=0.78 id=26% cov=23%
-----LLLSGGLDSAVVSTVLKpfleASGQE--YLSFTVGQEGSPDVTAARMMSEFLGTKHHE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B6ASY4(35-204:243) Phosphoadenosine phosphosulfate reductase n=1 Tax=Rhodobacterales bacterium HTCC2083 RepID=B6ASY4_9RHOB  E=0.0003 s/c=0.28 id=31% cov=22%
----IALVSGfGADSAVLLHLAAQLVPDMPVLFLDTGKHFNETLQYQRELASELG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A0KH87(45-124:290) Putative uncharacterized protein n=2 Tax=Aeromonas RepID=A0KH87_AERHH  E=0.0004 s/c=0.59 id=21% cov=24%
-----VSFSGRLESCYSMDLCRASGIRIRAITLDSPTRSRKEVARAKRYCQRYGIEQRVI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D0LKN0(55-262:292) PP-loop domain protein n=1 Tax=Haliangium ochraceum DSM 14365 RepID=D0LKN0_HALO1  E=0.0004 s/c=0.23 id=20% cov=74%
--RIMVCISGGKDSYALlevLRILQRRApvrFELLAVNVDQGWPGYDTAIIAEHLAST-GVPYRMITR-------------DFASVVEANLAPGATPCSLCSRLRRGVLYNLAGEFA----CTKIALGHHADDLIETLMLNLMYSGKLAAMPAklHSDDGRNTVIRPLAYVPEA---LLSSYAQEREFPVVR------------CG-CPSCGL--------------------------
>UniRef50_A8SRI4(36-96:497) Putative uncharacterized protein n=1 Tax=Coprococcus eutactus ATCC 27759 RepID=A8SRI4_9FIRM  E=0.0008 s/c=0.76 id=27% cov=24%
-KHCVCGVSGGADSVSLITVLVRlcgyLGIELHVVHINHmirGAAADSDQEYVEELCRKYGV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B3DR08(46-204:388) tRNA(Ile)-lysidine synthase n=10 Tax=Bifidobacterium RepID=TILS_BIFLD  E=0.001 s/c=0.29 id=19% cov=67%
---VLVACSGGRDSMALAAVSHivctSMGVRCGVVIVDHGLQEGSEqvAGEAANRCRALGLGPVIV----------RNATVQARGEGLEAAARQARYNELCAAARESGAIAVLLAHTMDDQAETVLIGLL----------RSRGVDALAGMPQVFTRSGVTFARPLLTLTRAETTGICEDLG-------------------------------------------------------
>UniRef50_B8GJL3(2-221:221) 7-cyano-7-deazaguanine synthase n=6 Tax=Euryarchaeota RepID=QUEC_METPE  E=5e-53 s/c=0.95 id=31% cov=92%
--KAVCLLSGGMDSSTLAYVAKDMGYHIHALHLNYGQRTEkKELQSATAIARSLSAEEFIPLDLGYFKAFGKSSLTDPAIDVDVFDENRPELPNTYVPFRNANLLSIATSFAESRDADAIFIGVQALDYSGYPDCRPAFIQAFQQVMDLGTadGTHIDLLTPFIGLTKTDILRKGLD---LGVPYEHTWSCYQNEE-KACGVCGSCHFRQKAFAELGLSDP-------------
>UniRef50_Q1QVW9(30-245:251) 7-cyano-7-deazaguanine synthase n=23 Tax=Proteobacteria RepID=QUEC_CHRSD  E=4e-51 s/c=0.94 id=34% cov=94%
--KAVVIYSGGMDSYTVLHRALRAGFEVHALSFHYGQRHSRELETAHDVCQRLGIAHQVVDIRAIHGLIGNSALTDATQTMPDGDYDADNMAATVVPNRNMILLSLAIGHAVNIGANVCFYGAHGGDHVLYPDCRPEFVERMNDVAAIADFTPVRIAAPYLHASKEEILADGLA---MGLDYAQTWTCYLGAE-RSCGHCGSCRERLAAFAAQGVTDPLVYA---------
>UniRef50_B2UN88(4-220:223) ExsB protein n=6 Tax=Bacteria RepID=B2UN88_AKKM8   E=1e-50 s/c=0.93 id=30% cov=94%
META-VLLSGGLDSSVALHWAHRNHRVRVALSFDYASNHaERELKCAAWQAASLGIE-HRVIDISSISSHLKSALLSGADDIPDGSYDEELMKQTVVPFRNGIFLSIAAGVAESCGAQQLVIAAHSGDHSIYPDCREEFMAAMTEAIRLGTYAGLGILRPFIHMSKGGIAAMGQD---LGVDFSRTYSCYKGG-AVHCGVCSTCMERREAFREAGIPDPTAYA---------
>UniRef50_Q1QCP3(28-259:259) 7-cyano-7-deazaguanine synthase n=122 Tax=Bacteria RepID=QUEC_PSYCK   E=2e-49 s/c=0.85 id=39% cov=94%
---AVVLLSGGLDSVTCLYWAKARYASVTAVSFDYGQRHNSELVAAKAIAETAGVNHRIIDI--DIAQLGGSSLTDHSMIVPDGdtdkfpdkkrdEIDNDAIPNTYVPARNTIFLSYALAVAEVTDSNHIVIGVSSVDYSGYPDCRPEYIAAFQHMANLATKAGVTghhlsIQTPLQQLSKAKTIELGLS---LGVDYGQTISCYQADaNGLACGVCDSCALRRQGFAQAGVADPTHYQS--------
>UniRef50_Q1IHK6(10-230:237) 7-cyano-7-deazaguanine synthase n=9 Tax=Bacteria RepID=QUEC_ACIBL   E=2e-45 s/c=0.83 id=36% cov=94%
--KAVVVLSGGMDSTVCATLAVREYgaENIGALHVSYGQRtAAREKQAFAAVAERLGIQTRLAVETPFFRAIGGSALTDANIAVPDaGELIGHEIPVTYVPFRNAHLLAMAVSWAEVLGASKIYIGAVAQDSSGYPDCRPEFYEAYNLAVRRGTkAGDIEVVTPLIALRKHEIVSLGL---ELGAPFDLTWSCY-SREDCACGVCDSCVLRLRAFEGAGAVDPVPYA---------
>UniRef50_Q8UAM7(1-220:236) 7-cyano-7-deazaguanine synthase n=71 Tax=Alphaproteobacteria RepID=QUEC_AGRT5  E=2e-45 s/c=0.84 id=34% cov=94%
MKTIVI-CSGGLDSVSLAHKIAAEHELLALVSFDYGQRHKKELDFAADCAKRLGVPHHLIDIGTIGAHLTGSALTDD-IDVPDGHYAEETMRSTVVPNRNAIMLTIAFGLAAAQQADAVAIAVHGGDHFIYPDCRPGFIGSFNAMQAHALEGyaDVTLFAPYVTVSKAAIVTDAVKYGT---PFGETWSCYKGG-LRHCGRCGTCVERREAFHLAGVTDPTEY----------
>UniRef50_D1R557(2-216:221) Putative uncharacterized protein n=1 Tax=Parachlamydia acanthamoebae str. Hall's coccus RepID=D1R557_9CHLA  E=3e-45 s/c=0.86 id=33% cov=89%
--KAIVLLSGGLDSAVMLARLHEQQIETLAISFDYGQRHRVELEFAKKIADFYGIE-HEVIPIDPLIFRGGSALTSSATPQKGKSKEdilKQSIPFTYVPARNTLFLAYALAKAEMHGADQIHFGSNAMDFLSYPDCRPGYFEAAQELFNRATKQSVEgkapqIVTPLLKWTKEEIVKEGYR---LKVPFELTSSCYDPTaNGQPCQQCDACTLRQDAF---------------------
>UniRef50_UPI0001C418E0(3-207:211) queuosine biosynthesis protein QueC n=1 Tax=Methanobrevibacter ruminantium M1 RepID=UPI0001C418E0  E=7e-45 s/c=0.89 id=29% cov=89%
-KDVVLILSGGLDSTTLLYKLLNEGNNVTALSFNYGQKAAIEIERASEICKMNDVNHFVFDIRNIVDLLSSSLTDKDNDNVQE-------PKSTVVPSRNTILLELATAFAISNNLEEVYYGAIKADTGDYPDTTPEFLKQINELNKVNNYEYIPVCAPFIDTDKKDVVKLAL---ELGVPIEKTWSCYVNNDGTPCGECFSCKSRIEAIKEAKEE---------------
>UniRef50_Q7M8H4(14-229:233) 7-cyano-7-deazaguanine synthase n=2 Tax=Campylobacterales RepID=QUEC_WOLSU  E=1e-43 s/c=0.82 id=45% cov=91%
---ALVVFSGGQDSTTCLGWAIKHFKSVEAITFDYGQRHRIEIEQSRLIAQKLGIKQFILEFDLFSKLGDSALLETSSDLKASPHRTKPHLPASFVPNRNALFFTLAHAYAQREGLTHIITGISEADYSGYPDCREEFITHLERTLNLGSDSSILFAYPLLHRNKAQTFALAKECGVLDLVLEESHTCYNGDRshryewGYGCKECPACGLREKGWREY------------------
>UniRef50_D2RLP8(3-229:232) ExsB protein n=3 Tax=Bacteria RepID=D2RLP8_ACIFE   E=4e-42 s/c=0.76 id=29% cov=93%
-KKALVLSSGGVDSTTCVSVAVEEFgkENVSTVSIFYGQKHRKELECARKVAEYYGLPHYELDLSKIFQYSNCSLLDHSTEEIvhesyeQQIAENGEGKVSTYVPFRNGLMLSAVASLAMSIyekDDVSIFIGAHADDAAGnaYADCSEAFIGAMGKAISLGTYNQCHIVAPFASCSKAGVVKRGL---ELHTPYDLTWSCYEGG-DKPCGTCGTCIDRARAFAANGVKDPA------------
>UniRef50_Q0W7U0(1-218:222) Succinoglycan biosynthesis regulator n=1 Tax=uncultured methanogenic archaeon RC-I RepID=Q0W7U0_UNCMA  E=5e-40 s/c=0.76 id=24% cov=90%
------MLSSGLDSVVAFKKEHDEHGVALAITFDYGQRaASKEIEMARQICARYHVR-HEVIELPWLKQITRTALVSRQAEVPEPTEAEldeikgralETAHLVWVPNRNGAFINIAAAFGDAYGYNRIVCGFNAEEGATFPDNTPAYVDAVNKSLALSCEKQVQVVAPVIHFDKEEIIREGVRI---EAPLDLSWSCYFAGE-KPCGKCESCMRRARAFKRAGVPDPS------------
>UniRef50_A8AAU7(4-237:260) ExsB protein n=1 Tax=Ignicoccus hospitalis KIN4/I RepID=A8AAU7_IGNH4  E=6e-40 s/c=0.71 id=31% cov=91%
----VGLVSGGMDSATAFADAInKFNPDVkVALTVVYGQRHARELKAAAEVAKFYGAQHLVVDLSDLFEKVKEVSALLGGRGVPEAEELVPGLvPPTYVPQRNAVLLASAGAILEKLmierndGLGVISVGFHGTDYAPgepvYPDTRPEFVEAMERALNEGSsvvfnfkragrEAKITIYAPFVRLKKKDVVKRAL---ELGVPLELTWTCYRGG-DRPCGTCPACVSRLRAFMEAGVPDP-------------
>UniRef50_B4E7W5(10-234:244) 7-cyano-7-deazaguanine synthase n=73 Tax=Bacteria RepID=QUEC_BURCJ   E=3e-39 s/c=0.73 id=47% cov=90%
---ALVLFSGGQDSATCVAWALERYQTVETLGFDYGQRHRVELECREGVREAL---KHRFPAWSDRlgddhmidLSVLGAISDTAMTRTIEIETTANGLPNTFVPGRNLMFMTIAAAIAYRRGLRVLVGGMCETDFSGYPDCRDDTMKALQVALNLGMDTRMVLETPLMWLDKAQTWQLAEQLGgdaLVELIRVETHTCYVGERAElhdwgfGCGECPACKLRKRGYEAYL-----------------
>UniRef50_D2R400(10-222:236) ExsB family protein n=1 Tax=Pirellula staleyi DSM 6068 RepID=D2R400_9PLAN  E=1e-33 s/c=0.68 id=24% cov=90%
-----VLMSGGLDSSILVGKFLREGRTVHPIYIRTGLFWQSgELPAVQAFLAAIataNLRPLKILELPLDDLYTDHWSLTGSGTPADDTPDE----AVYLPGRNALLLVKAAVYCQLHGIGQLACAPLG--SSPFEDASSEFFTEYQSAMNRGSSSPVVLLRPFGELHKEEVMRLG-----VGLPLELTFSCIHPVDGTHCGTCNKCFERKEAFRITGIEDKTVYTA--------
>UniRef50_UPI00016C5260(20-231:232) ExsB n=1 Tax=Gemmata obscuriglobus UQM 2246 RepID=UPI00016C5260   E=3e-29 s/c=0.61 id=24% cov=90%
-----VLVSGGLDSAILLAEAVRACPVVFPLYVRSGLHWEAvERAYLERFLAAIaapNLRPLRVLDQPTADVYGAHWSTTGEG-VPGADSADE---AVFLPGRNVLLLAKPLIWCHLNAVPFVATAPLGTN--PFPDATPAFYDGFAGIVSSAVRGDVRVLRPYAALHKVDVMRRGR-----GRPLEHTFSCIRPVRGLHCGTCNKCAERRQAFRDAHMTDPTEYA---------
>UniRef50_D2PHM6(16-213:213) ExsB family protein n=3 Tax=Sulfolobus islandicus RepID=D2PHM6_SULIS  E=2e-28 s/c=0.65 id=25% cov=86%
--KFLLLFSSGLDSSSVAYYYAKKSLDFDCLFINYGQSSvRMQLKYGKIICEKL-KRRLIIINAKNLGEAFVN--------------NDWLRPHEPIIHRNLVIVPIAIAYAKQNGYERVIMATIREDCEYEPNRR----DVMEKLKELGEILGVRFETPFVNFPKYLLLKIGIKSG---LDPSLTYSCLLGHK-YHCGKCSQCLKRIEAFKQAKIRDPTIYK---------
>UniRef50_B1XTB6(22-201:208) ExsB protein n=1 Tax=Polynucleobacter necessarius subsp. necessarius STIR1 RepID=B1XTB6_POLNS  E=2e-28 s/c=0.71 id=31% cov=74%
-----------IDSTTVLALAKDSDYTPYALSVGYGQRHSSELAAAKHIAKQIGVARHEVVNLD-LTRFGGSALTDTKIAVPTSPGKDHEIPVTYVPARNTILLSLALGWTESLGGLDIFYGANSVDYSGYPDCRPECVASFEHMANLATKAGVeainnknrfRVHAPIVSLTKAQIIQLG---STMGVDYSQT----------------------------------------------
>UniRef50_Q2RGB7(1-185:192) ExsB n=1 Tax=Moorella thermoacetica ATCC 39073 RepID=Q2RGB7_MOOTA   E=2e-25 s/c=0.63 id=21% cov=80%
MNPVLVLLSGGIDSAALVHYYRSKNTSVYGLHVQYGQPvAEREAQAAKAIAAHYGIDLRIAHIQPPLARKGEEYL-----------------------CRNAIFVLIACAN-LSPGINRVALGIHSG--TIYYDCSQGFMADMQRLLDGYFSGAVTVEAPFLRWSKLEVYQYCTSHG---VPVDLTYSCERN-NDEPCGQCPSCYDRRRLYEAG------------------
>UniRef50_Q989H2(1-194:198) Mll6423 protein n=2 Tax=Proteobacteria RepID=Q989H2_RHILO   E=3e-25 s/c=0.60 id=28% cov=79%
MTTAL-LLSGGMDSVSIAWWLRPD----VALTIDYGQKPaEAEIDAAGHVAQLLGISHEVI---------RVDCSSLGSGDMAGTAPDAAAPVSEWWPFRNQLLVTLAGMAAVRHGVSRLLIGALATDGA-HADGRPEFVERASQLMAM-QEGGIVVEAPAIELDAVELVR---RSGIDQGTLAWAHSCHTG--NYACGRCRGC----------------------------
>UniRef50_Q8R5Z5(1-202:343) tRNA-specific 2-thiouridylase mnmA 2 n=12 Tax=Fusobacterium RepID=MNMA2_FUSNN  E=3e-25 s/c=0.58 id=22% cov=84%
MKKVVIGMSGGVDSSVSAYLLKEQGYEVIGITLNQHLEEnSKDIEDTKKVCDKLGIIHEVVNIRKDFENIVIKYFLEG--------YNSGKTPSPCIICDDEIKFKILFDIADKYNAEYVATG-HYTSVEYSEVFSKYLLKSVHSiikdqsymLYRLSPDKLERLIFPLKDYSKQEIREIA-----LKIDLEVH------DKKDSQGVCFA----KEGYKEFLKEN--------------
>UniRef50_A8AM74(155-377:446) Putative uncharacterized protein n=8 Tax=Gammaproteobacteria RepID=A8AM74_CITK8  E=3e-24 s/c=0.51 id=19% cov=81%
----VSLFSGGLDSAIGVIDFLSSGRKPLLISHSY----KGDKTKQDQIA-------HKIREKGTFSRLRSSANPIGRGMTRDI----------TMRTRSLNFLAFALVGAYAvkqinnHKDLSIFVPENGfislnaplthrrVGSLSTRTTHPYFIGMIQELFN-NLGFGVRLINPYQFMTKGQMVSNCKDSKMLSEIVDLTVSCSHWKRkNQQCGYCVPCMIRRAALMKG------------------
>UniRef50_Q5JCY1(182-340:381) Probable tRNA sulfurtransferase n=14 Tax=Thermococcaceae RepID=THII_PYRKO  E=2e-23 s/c=0.70 id=20% cov=69%
--KVVALLSGGIDSPVAAFLMMKRGVEVIPVHIYMG---EKTLEKVRKIWNQL-KKYHYGGKAELIVVKPQN-----REEMLKKIKELGKEKYTCVLC-KFMMVKHADRIAKEFGAKGIVMGDSLGQVAS---------QTLENMYIVSQASDLPIYRPLIGLDKEEIVDIAKKIGTFEL---------------------------------------------------
>UniRef50_A0B2R8(140-359:428) Putative uncharacterized protein n=4 Tax=Burkholderia cenocepacia RepID=A0B2R8_BURCH  E=9e-23 s/c=0.50 id=18% cov=87%
----VCLLSGGLDSLVGALDLTEEGRHPLLVS----QTAKGDKETQSRFAIGLGGNDRHLQ-----------WNQNIRPKVEDIEGSTRGRSIGFFAFAAVAADHLATTITALPRPVEVFVPENGLISLNIPLNpgrvgslstkttHPVFMARLQALWDE-LGIRAVLRLPYAAMTKGEMMAECRASTVLADVASEATSCGRFVRNgyKHCGRCVPCLVRRASFIRANLRDDTTY----------
>UniRef50_A1SFM8(1-177:183) ExsB family protein n=1 Tax=Nocardioides sp. JS614 RepID=A1SFM8_NOCSJ  E=3e-21 s/c=0.59 id=28% cov=75%
MKRpatdICVLLSGGVDSALVLAMLSNRS--PVSVWVDYGQPvADVERQASRAIANHFGSPWMEVVIKGL-----------------------APPASGEFLGRNDLLVAAALSVA---GGGFVAIGTHAG--TGYADCSLAWAGSWQALLDAQHGGTAGLLAPLSNLDKAQVYELAVANG---VPIELTHSCETT--AAPCGSCSSCADRR------------------------
>UniRef50_A4T1U6(144-374:454) Putative uncharacterized protein n=2 Tax=Actinomycetales RepID=A4T1U6_MYCGI  E=3e-21 s/c=0.45 id=21% cov=84%
---AVSLFSGGLDSLTGVIDLLEEdpDRRLCLISHNEGdQASTAQKTLTAALREHYGQDRLEL----------RSLFLRPAPAVAGQARPLPPERETTTRARSLLFLTAGLALAASVGPDVpVYIPENGfiginvpltrarSGSYSTRTTHPQFMQLLRTAAD-AVGVCNPILNPFRLKTKGEILASSRNPELLRSLAPNSISCSHPEAARyavrkqgNCGYCFPCLIRR------------------------
>UniRef50_A3W978(147-368:446) Putative uncharacterized protein n=2 Tax=Rhodobacteraceae RepID=A3W978_9RHOB  E=7e-21 s/c=0.46 id=20% cov=87%
----VSLFSGGLDSLIGAIDLLASGQRPLLVSHYWDGEASS---AQRQLLEVLKERH------DGAFESVRAYIGFRKSDFAEAGSDNNQ------RARSFLFYSLAVVAADAVAstnkvlipengliALNVPMDAHRLGSLSTRTAHPHFIRSMSQLV-TALGVDVTLENPYRFKTKGEMARECGDRDLLAELAPVSMSCSHPAQVRfesappqHCGRCVPCLIRRASLAVGLDEaDTTKY----------
>UniRef50_A0PSW2(135-349:420) Putative uncharacterized protein n=1 Tax=Mycobacterium ulcerans Agy99 RepID=A0PSW2_MYCUA  E=1e-20 s/c=0.47 id=20% cov=83%
--DAVSLLSGGLDSLSGAVL---KGAPGLFLSH----TDNPTVTGAQR--------------------RTWNWLTSNGVEGECVRlslNEASRKRENTTRTRALLFYALAVALADARGIDRVEVSENGftglnlslgndrGGVLSTRSTHPWTMHLMQRLLDDA-GIDIELVNPYEWQTKGELVRAAADvCPAFAEGLVTTLSCakldgrtYKGGNpNLNCGLCVACLTRRASIRAAGLEDKTPY----------
>UniRef50_A5FHA9(1-218:395) tRNA-specific 2-thiouridylase mnmA n=26 Tax=Bacteria RepID=MNMA_FLAJ1  E=5e-20 s/c=0.46 id=30% cov=50%
MKRVVVGLSGGVDSSVAAYLLQQQGYEVIGlfmknwhddsVTISNECPWLEDSNDALLVAEKLGIPFQTVDLSEEYKEKIVDYMFN--------EYEKGRTPNPDVLCNREIKFDVFMKIALSLGADYVATG-------------------------------------------------------------------------------------------------------------
>UniRef50_C7RPK0(150-387:458) Putative uncharacterized protein n=1 Tax=Candidatus Accumulibacter phosphatis clade IIA str. UW-1 RepID=C7RPK0_9PROT  E=7e-20 s/c=0.42 id=21% cov=89%
--DSLCLFSGGLDSLIGAINLLQAESAPLLIS-HFGESATSDAQN------KLFAKLKKQYARSAFDRLRVGMTFDDGL-VKDVGSENSTRGRSFLFFALGVFAGTGLRNGFTLKvpengliALNVPLDPLRLGSNSTRTTHPYFMARWNDLLDE-LGIDGRVENPYLPMTKGEMVLACANQKLLLELAPMSLSCahpanarwqgHKGRGIEHCGYCLPCLIRRAALNRAWGE---------------
>UniRef50_B4R9S2(150-384:456) Putative uncharacterized protein n=1 Tax=Phenylobacterium zucineum HLK1 RepID=B4R9S2_PHEZH  E=1e-19 s/c=0.42 id=14% cov=94%
--DSVCLFSGGLDSFIGAIDLLADGKAPMLVSHYWdGITSTHQTYCADVIAKRFPKQRFHHLRARVGFPNDLVDGSAGENTLRGRSFLFFALAAMAADALGVGLIHVPENGLISLN---VPLDPTRLGALSTRTTHPFYMARFDEILD-GLGLPIRLENRYRFQTKGVMAKNCADAALLNKEARHTMSCSSPAKARwakdedarqpkHCGHCVPCLIRRAAMVEGLGADHTPY----------
>UniRef50_C5PNW4(8-187:198) ExsB superfamily protein n=1 Tax=Sphingobacterium spiritivorum ATCC 33861 RepID=C5PNW4_9SPHI  E=3e-19 s/c=0.54 id=22% cov=78%
-----LLLSGGVDSICLAYGLKPD----IAYTINYGQiPASREIYVSRYICNLLRIQHKVIE---------VNCKSLGSGILINEERLDISPSQEWWPYRNQLLITLAAMQAIKDKIGVLHLASVKSDSF-HKDGTPQFYDLINELVKY-QEGNISIVCESTGYYSHELVK---KYNVPLEIIAFAHSCH--ISNTACGQCPGCK---------------------------
>UniRef50_C5CE34(177-335:404) Thiamine biosynthesis/tRNA modification protein ThiI n=1 Tax=Kosmotoga olearia TBF 19.5.1 RepID=C5CE34_KOSOT  E=6e-19 s/c=0.61 id=22% cov=66%
---ALLLLSGGIDSPVAGWYALKRGITLHAIHFASpPYTGEKAFEKVLDLAKAL----------TKYNGGRDMLLYRVHFTKLQLAIHRNVRESLSLVIQRRAMMRIATKIAKEHGYKAIVTGENLGQVAS---------QTIENLHTIGSATDILVLRPLTGFDKIETIQIAKK---------------------------------------------------------
>UniRef50_A6W0E1(31-235:390) tRNA-specific 2-thiouridylase mnmA n=20 Tax=Bacteria RepID=MNMA_MARMS  E=2e-18 s/c=0.46 id=21% cov=72%
-KKVIVGMSGGVDSSVSALILMQQGYQVEGLFMKNWDEddgteyctAKDDLADAQAVSDKLGIKLHT--------ANFASEYWDNVFEHFLAEYKAGRTPNPDILCNKEIKFKAFLEYAMALNADYIATGHYVR--RGEKNGEPLLLKGLDGnkdqsyfLYAVGKDEIAKTLFPVGELEKTEVRRLAEEFG-------------------------------------------------------
>UniRef50_A2PQ54(151-369:444) Putative uncharacterized protein n=1 Tax=Vibrio cholerae MZO-3 RepID=A2PQ54_VIBCH  E=2e-18 s/c=0.43 id=16% cov=81%
----VSLFSGGLDSAVGAIDMINGSnvDKPLLISHSYKGDGKKQ--------------------KDIKSLLRGKFSEFSFDISPKIIKSRRGKTDVSMRGRSFNFIALAVLGVNALRsannddsISRIVIPENGyislnppltrrrIGSHSTRTTHPFYISRLELLLNK-VGFNISLENPYQMKTKGEMVSECVDKVAIKKAVVLSVSCSNWHRKHiQCGRCVPCLIRRAAV---------------------
>UniRef50_D2MP56(177-333:472) Thiamine biosynthesis/tRNA modification protein ThiI n=1 Tax=Bulleidia extructa W1219 RepID=D2MP56_9FIRM  E=5e-18 s/c=0.60 id=21% cov=67%
--KVMMLLSGGIDSPVATYQLIKRGLKVEAVHFAAPPYTS---EAAKNKVLKLAS-----MISDYQGGMKVHVVPFTELQLDIYRVAKDPYAITLM---RRMMFRIAEKLAINNRCLAIGTGESLGQVAS---------QTLESMVTINDVVHIPVLRPLVSMDKVEIIQLAREIG-------------------------------------------------------
>UniRef50_Q1GAV1(173-330:399) Thiamine biosynthesis protein ThiI n=10 Tax=Bacilli RepID=Q1GAV1_LACDA  E=6e-18 s/c=0.59 id=20% cov=68%
--KAVMMLSGGIDSPVASYLAMKRGVNIEMVHFFSpPYTSEKALAKAKELT---SILAKYSGRINFIEVPFAEIQETIKEKLPEGYLMTVQRR---------FMLRLADIIREKRHALAIFNGESVGQVAS---------QTLESMAAINNVTTTPVLRPVATMDKTEIIAKAEEIGTFDL---------------------------------------------------
>UniRef50_A7I9Z5(172-330:370) Thiamine biosynthesis/tRNA modification protein ThiI n=4 Tax=Euryarchaeota RepID=A7I9Z5_METB6  E=7e-18 s/c=0.59 id=19% cov=67%
----VALVSGGIDSPVATYMMMKRGCKIVPIYVALEtFLDETVLARAERVVEIL----RQYQPDLKLRVIHDSYLAAAKEELIRNHQEKYT-----CLFCKRRMYRIAQAVAQEVGAKGIVNGESLGQVAS---------QTLDNLVVLSDVAEIPVYRPLIGFDKADAIALAREIG-------------------------------------------------------
>UniRef50_Q8A2F1(6-187:370) tRNA-specific 2-thiouridylase mnmA 2 n=8 Tax=Bacteroides RepID=MNMA2_BACTN  E=2e-17 s/c=0.50 id=39% cov=24%
-KRVLLGMSGGTDSSVAAMRLLEAGYEVTGVTFRfYELNDSTEyLEDARHLAERLGIR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q0A9U9(205-362:422) Thiamine biosynthesis/tRNA modification protein ThiI n=1 Tax=Alkalilimnicola ehrlichii MLHE-1 RepID=Q0A9U9_ALHEH  E=3e-17 s/c=0.58 id=24% cov=65%
--RALTLLSGGIDSPVAAFLMAKRGCRVDFLHFTaspSQQRADADhtvIRLARQLSRYTGHSRLYMVPYDHF----------------DMALHGDQRGHEVVLFRRFV-ARTGEALAKRLRALALISGDSLGQVAS---------QTMENMVSTSLAVRMPIMRPLVGLDKADIVAIGRRIG-------------------------------------------------------
>UniRef50_D0WEQ1(184-341:421) Thiamine biosynthesis/tRNA modification protein ThiI n=1 Tax=Slackia exigua ATCC 700122 RepID=D0WEQ1_9ACTN  E=4e-17 s/c=0.57 id=23% cov=68%
--KVVCLLSSGIDSPVALWRMARRGATCVAVHFSGRPQTQATSEFiVDDIA-------HTIEGFGGIARMYVVPFGDYQRTIAGTVPQRLRI----IVYRRLMM-RVAAAIARREGAKALVTGESLGQVAS---------QTLDNLAATGSAVDMQVFRPLIGSDKLEIIADAQKLGTFDL---------------------------------------------------
>UniRef50_C4FTQ9(180-337:404) Putative uncharacterized protein n=1 Tax=Catonella morbi ATCC 51271 RepID=C4FTQ9_9FIRM  E=4e-17 s/c=0.57 id=20% cov=65%
--RALLMLSGGIDSPVAGYQMMKRGLEIEAVHFASPPYTSPQaIEKTKKLTAQLaqygrSLTYHCVPFTEIQEEIKDKVHDDFSMTIM-----------------RRMMLRVMEALLDRQQADAIVTGESLGQVAS---------QTLKSMRAINQVTSVPILRPLIAVDKNDIIVQAEAIG-------------------------------------------------------
>UniRef50_A0YNH9(158-374:488) Putative uncharacterized protein n=2 Tax=Oscillatoriales RepID=A0YNH9_9CYAN  E=7e-17 s/c=0.41 id=19% cov=86%
----VALWSGGLDALAGLYTRLQTSHTVPFMLFGTGSSksvYARQEKVFQAIIKSF---PTHLYLCRVPINFLNSKLL---------------RKNKITRARGVVFTLLGAACAYLMGQRTLSVYENGIGAInlpyrasavgldHSRSVHPLTLLMVSDVVSELLGENFRVYNPFLFLTKAQICR-ALAENQENDLVAITQSCdsrhRKSQQPTQCGYCSSCILRKQALAASKIEDKTRY----------
>UniRef50_C8WW19(179-336:400) Thiamine biosynthesis/tRNA modification protein ThiI n=2 Tax=Alicyclobacillus acidocaldarius RepID=C8WW19_ALIAD  E=8e-17 s/c=0.57 id=23% cov=67%
--KGLVLLSGGIDSPVAAWKAMKRGLALELVHFHsFPFTSERAQQKVEDLAAIL----------TKWGGPMKLHLVSVTAIQAEIQRSAPEGLRTILLRR--MMVRAASRIADEVGAGALVTGDSLGQVAS---------QTLSALNAVDRATDHTILRPLIAEDKLEIIELAKRMG-------------------------------------------------------
>UniRef50_Q8R5X3(25-188:362) tRNA-specific 2-thiouridylase mnmA 1 n=16 Tax=Fusobacterium RepID=MNMA1_FUSNN  E=9e-17 s/c=0.54 id=29% cov=24%
--RVGVAMSGGVDSSTVAYLLKQQGYDIFGVTM---KTFKDEDSDAKKVCDDLGIEHYIL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B0RZV0(190-337:391) Probable tRNA sulfurtransferase n=7 Tax=Clostridiales Family XI. Incertae Sedis RepID=THII_FINM2  E=2e-16 s/c=0.60 id=17% cov=63%
-----------IDSPVAAFLMAKRGVRVDCLHFHsYPFTSQRGFEKVKQLAEEVS-----------YYTGNINFYSVNLLPVYKAITKNCKERMMTIISRRFMM-RIAERIANENKIDALITGESLGQVAS---------QTIQGVSVINEVTSLPILRPLIASDKTEIIEIAREIG-------------------------------------------------------
>UniRef50_A9SZR3(40-224:421) Predicted protein n=1 Tax=Physcomitrella patens subsp. patens RepID=A9SZR3_PHYPA  E=2e-16 s/c=0.47 id=20% cov=70%
--------SGGVDSSIAALLLQRQGYEVFGVYMRNWDardeaggghcSADQDYEDAQRVCEHLaGIKLHHLDYQKKYWTQVFENFTQKFAMGLTPNPDLD--------CNQHIKFDALLENALQMGADKFATGHYARLSRPQCGGPVQLLRGIDEdkdqsyfLASVGSAAFERVLFPLGGLTKAQVRDLALSEG-------------------------------------------------------
>UniRef50_A1U6U9(179-334:484) tRNA sulfurtransferase n=11 Tax=Gammaproteobacteria RepID=THII_MARAV  E=3e-16 s/c=0.56 id=24% cov=66%
-ETVMTLISGGYDSSVAAYLMMRRGIRSHYLFFNLGG-AAHEVG-VRQVAHYL-------------WERYGSSHNVKFISVPFEGVVAEIMRSVnhrhWGVVLKRMMLKAAAEIARDYNASGLVMGDAVAQVSS---------QTLTNLNVVDRASDEVVLRPLIAMDKQEIIRIAKDIG-------------------------------------------------------
>UniRef50_D0LKN2(189-347:401) Thiamine biosynthesis/tRNA modification protein ThiI n=1 Tax=Haliangium ochraceum DSM 14365 RepID=D0LKN2_HALO1  E=3e-16 s/c=0.55 id=22% cov=66%
-----LLLSGGIDSPVAGWSAMRRGCRVVAVYFHsFPYTGDKTKKKVLTLAQRLaawqgSVPVHVVHFTEVQKAL---------------REHAGGRADLGVLMYRRMMLRAASRLALRDELSALVTGDSIGQVAS---------QTVENLGVVEDAASVPVLRPLLTFDKAEIVERAQQIGTYEV---------------------------------------------------
>UniRef50_A4BQF8(207-364:441) Putative uncharacterized protein n=1 Tax=Nitrococcus mobilis Nb-231 RepID=A4BQF8_9GAMM  E=8e-16 s/c=0.55 id=16% cov=68%
---VLSLLSGGIDSPVAAFLMAKRGCRVNFLHMTATHLAADRLREnlVSRIAKRLSIYTLRSRLFLVPYTHFDLALI-----------GQPPSGFEMILFRRFI-ARLGTRLVERHGGQALVVGDSLGQVAS---------QTLENIVSHSQATALPILRPLIGMDKQEIVERARTIGTYEL---------------------------------------------------
>UniRef50_A8M9I7(181-347:416) Thiamine biosynthesis/tRNA modification protein ThiI n=1 Tax=Caldivirga maquilingensis IC-167 RepID=A8M9I7_CALMQ  E=8e-16 s/c=0.52 id=17% cov=65%
--KVLALVSGGFDSPVAYWLMSRRGALVDALFCSLAPP-----------VDVIGLIR-VIRYLYENWVFGYDPLIMIADCTQLVNAMRSSVNSHLM---NTVFkkflYRLAESIAVEGGYMGIVTGESLGQVSS---------QTLSNLYSASAGINVPIFRPLIGMDKDDIIKLAKRIG-------------------------------------------------------
>UniRef50_Q9HKT9(170-328:481) tRNA sulfurtransferase n=2 Tax=Thermoplasma RepID=THII_THEAC   E=9e-16 s/c=0.54 id=16% cov=66%
--KYISLVSGGIDSPVSTWMIMKRGspCDILFCSLSYPVDLRPFVDVVKKLVERW-------APYRKPRIYVADCRSLIRTMVIEGRTKYSNVTFKRVIYR------IAEKIALENGYNGIVTGESLGQVSS---------QTAENLKAIESGIGVPILRPLIGMDKDEVVDMARRIG-------------------------------------------------------
>UniRef50_Q4A546(170-338:353) Thiamine biosynthesis protein (Fragment) n=2 Tax=Mycoplasma hominis RepID=Q4A546_MYCHO  E=3e-15 s/c=0.50 id=19% cov=68%
--KCIHLISGGIDSPVAANLLQKRGLKIVFLnFITPPQTDEKTIAKIDEI-------------VNILKKYQGNAMLYqiNYSKVMEYIGLISNQKYKITLMRRS-FYRIANLIAKKENIKAISNGENLAQVAS---------QTLESIYTISEVCDLPIFRPLISFDKNETIAIAKKINTLDV---------------------------------------------------
>UniRef50_A8LMN3(39-241:479) Putative uncharacterized protein n=1 Tax=Dinoroseobacter shibae DFL 12 RepID=A8LMN3_DINSH  E=1e-14 s/c=0.41 id=19% cov=81%
----VLMFSGGLDSLSGAVeEIAEHGQRVALVSHFSATKiAPVQRYMQRSLADAFGAN-------------------TCQHVPVQVQMMGRSLKEGTHRSRSFLFAALGAITAEAFDLNRVSFHENGVVSLNlppvgnvlgtraTRTTHPQTLSRFTALLGQVFQGAMRVDNPYFWRTKKEVVETIARLN-MAEQIAVSRSCAdvhnQTRQHPHCGRCSQCIDRLEG----------------------
>UniRef50_Q3AD57(1-214:338) Putative uncharacterized protein n=1 Tax=Carboxydothermus hydrogenoformans Z-2901 RepID=Q3AD57_CARHZ  E=1e-13 s/c=0.37 id=20% cov=81%
MVKALALFSGGLDSTLAIKLILEQGVEVEAVNFTSPFCRclakGQGCASTAKLAADLGIKLHVQNCGEEYLRIVENP------------PHGYGSALNPCIDCRIFKFKKAKKLMEEIGAKFMITGEVLGQ--RPNSQRRDAI----NLIDREAGIKGLVLRPLSALhfpptiaeqegyvSRDKLLAISGRSRKTQMELAASF----GINDYPCPS-GGCLLTKKEF---------------------
>UniRef50_C5CIB3(4-229:359) tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase n=1 Tax=Kosmotoga olearia TBF 19.5.1 RepID=C5CIB3_KOSOT  E=2e-13 s/c=0.35 id=20% cov=71%
-----VALSGGVDSAVAAAILKAEGHDVVGYHMknlpDTLFELVPEKKKVccspsdtidtHKIAAKLGIELRIVKLNDIFRKEIIDYFIR--------EYQAGKTPNPCVRCNDLMKFGALMEKAFGDGMEKFASGHYARIVEHPKYGlslARGVAKYKDQAYFLSRIKRRKlpyIIFPNGNMTKEEIRDIARELG-------------------------------------------------------
>UniRef50_P49915(238-436:693) GMP synthase [glutamine-hydrolyzing] n=87 Tax=Eumetazoa RepID=GUAA_HUMAN  E=3e-13 s/c=0.39 id=31% cov=23%
--KVLVLLSGGVDSTVCTALLNRAlnQEQVIAVHIDNGFMRKRESQSVEEALKKLGI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q9W5B6(14-211:389) Mitochondrial tRNA-specific 2-thiouridylase 1 n=7 Tax=Sophophora RepID=MTU1_DROME  E=1e-12 s/c=0.38 id=20% cov=75%
------------DSAVSAHLLAEQGFKVLGVFMRNWDEAdevgrcsgEADLKDAEWACRQLGVELRQVNYVREYWTAVFSQFLDDYQMGLTPNPD--------ILCNRHIKFDLFHKHAlENLGYDAVATGHYARNSlgnylegiASNNDARllipaDTFKDQTFFLAGISRKALQRTMFPLGDFQKSQVKDLAKKIGfqRLAKKKESTGICFVGKR--------------------------------------
>UniRef50_Q1AS35(5-193:409) Argininosuccinate synthase n=69 Tax=cellular organisms RepID=ASSY_RUBXD  E=8e-12 s/c=0.38 id=25% cov=68%
-KKVVLAYSGGLDTSVCLKWFEEQGAEPYALYLDLGQGEPAE--DVREKALRIGAREVFVWDARE------EFARDYVAPAIKANALYGGRYPLFTALGRPLIAKKLVEAARRVGATHIAHGSTGkGNDQVRFDVTTG-----------SLAPDLTVVAPVRDwnMNRPEEIEYARKHG-------------------------------------------------------
>UniRef50_B0ABE2(17-165:265) Putative uncharacterized protein n=1 Tax=Clostridium bartlettii DSM 16795 RepID=B0ABE2_9CLOT  E=1e-11 s/c=0.49 id=29% cov=29%
MGKVVIAYSGGVDSNFLLKVASdELGQNAIAVTIHAMMHSDREMDEAKEYTKQFGVK-HEVIKVDNFDE-------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B3QYF4(223-390:514) GMP synthase [glutamine-hydrolyzing] n=81 Tax=cellular organisms RepID=GUAA_CHLT3  E=1e-11 s/c=0.43 id=31% cov=23%
---AICAISGGVDSSVAAVLVSRAlGDKLHCIFVDNGLLRKNEAEKVQEKLKQLG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q01ZH4(27-171:281) ExsB family protein n=2 Tax=Acidobacteria RepID=Q01ZH4_SOLUE   E=1e-11 s/c=0.50 id=19% cov=49%
MERVLVAFSGGTDSAYLAWAARQvLGENAVAMTADSASLPESHKRDAEDFVRRFGIVHEYIET-----HEFDNPEYVRNDPNRCFHCKDE-------------LFTRLAEVGQARGYRHIVYGVNVDDLGDY----------------------------------------------------------------------------------------------------
>UniRef50_C9MRP4(21-167:461) tRNA(Ile)-lysidine synthase n=1 Tax=Prevotella veroralis F0319 RepID=C9MRP4_9BACT  E=1e-11 s/c=0.49 id=25% cov=24%
----LVALSGGADSVALLLTMRQLGYETDAVHCNFHLRgdeSNRDEEYCQSLCKQLNIPLHI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A4J0U7(19-165:270) PP-loop domain protein n=4 Tax=Firmicutes RepID=A4J0U7_DESRM   E=1e-11 s/c=0.49 id=32% cov=26%
--KVLVAYSGGTDSAFLLAVAvQELGDNVLAVTAISPTSTKAEVAEAQQLAKELGVHHRII---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C9L8M3(21-171:282) PP-loop family protein n=4 Tax=Bacteria RepID=C9L8M3_RUMHA   E=2e-11 s/c=0.47 id=35% cov=23%
-------FSGGVDSSLLLMLAKEcmkqqkKAGNIHAVTFHTVLHPPCDLEIAQKVAKEAGAV-HKVV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D2R113(1-195:404) Argininosuccinate synthase n=1 Tax=Pirellula staleyi DSM 6068 RepID=D2R113_9PLAN  E=2e-11 s/c=0.37 id=23% cov=60%
MPSCVLAYSGGLDTSVILGWLQDEGYEVHAVYVDLGQPCE-DRQAILKKARDCGAKSSQIVDAQE------ELCRDFAFPVMQFQAKYEGWYLLGTSIARPLISKVCLQIARDLGA---VAYAHGATGKGNDQCRFQLaAEALNPAVEV-----------------------------------------------------------------------------------
>UniRef50_B9CYH7(18-158:260) Putative uncharacterized protein n=3 Tax=Campylobacter RepID=B9CYH7_WOLRE  E=6e-11 s/c=0.50 id=24% cov=60%
-----VAFSGGADSSLLLRAAHgALDARAIGITIRSPYMSSREIAEAVEFARAYGIRHEIL-------------------ELGVAEGIKNNPENRCYLCKKAVFSRLIER-ARELGFSRVADGTNRDDLGEYRPG----LKAKEEL---------GVLSPLINLTKSEIRELSRELG-------------------------------------------------------
>UniRef50_A0LE34(7-169:407) Argininosuccinate synthase n=5 Tax=Bacteria RepID=ASSY_MAGSM   E=7e-11 s/c=0.43 id=32% cov=26%
--KVVLAYSGGLDTSIILKWLQDEYqCEVVAFCADLGQ--AEELEPARAKAEKFGVKEIYIDDL------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A8TGM5(16-165:250) ExsB family protein n=1 Tax=Methanococcus voltae A3 RepID=A8TGM5_METVO  E=8e-11 s/c=0.46 id=30% cov=29%
-KKVIVSYSGGVDSTLVAKLAQN-GEDCVAVTIDNGFFSKSSLKYAEKKAKLMNLK-HVIIDVNQLDE-------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A8AA65(1-161:396) Argininosuccinate synthase n=5 Tax=Archaea RepID=ASSY_IGNH4   E=1e-10 s/c=0.43 id=33% cov=26%
MSKIVLAYSGGLDTSVAVAWLKEKfGAEVITVTVDVGQK--EDFKEIEERAYKAGASKHYLID-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q2NHY4(53-174:319) Predicted ATPase n=5 Tax=Methanobacteriaceae RepID=Q2NHY4_METST   E=1e-10 s/c=0.57 id=32% cov=26%
--KVLVGLSGGKDSVALLKILnilkEKNIITLEAVTIDEGISGYREegIRIAKETAKALDIKHHIV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6DKP8(211-397:598) Bifunctional GMP synthase/glutamine amidotransferase protein n=1 Tax=Lentisphaera araneosa HTCC2155 RepID=A6DKP8_9BACT  E=2e-10 s/c=0.37 id=20% cov=71%
-KKVFLLVSGGVDSNVAFALLnKALGDEnVYGLHVDNGLMRKDESAWVKEELKQAGFSNFHVVDA-------GDTFLKNLAGVSEPQAKRVIIGDT--------FLDVKCEAVEEsdlvddswlLGQGTIYPDTIesgGTENSHLIKTHHNRVDRIQELINQG-----KVIEPLAELYKDEVRELGE---LLGLPHKLVW---------------------------------------------
>UniRef50_Q469Z8(3-168:395) Argininosuccinate synthase n=16 Tax=Euryarchaeota RepID=ASSY_METBF   E=2e-10 s/c=0.41 id=19% cov=71%
-KKVALAYSGGLDTSVCIPILKEKygYDEVVTISVDVGQ-PEEEIKRADAKAEKISNKHYTIDAKEEFVKDYVFPLIKANGSYEGYVMGTSIARP--------LIAKKVVEAARKEGAVALAHG---------CTGKGNDQLRFEAVFRQ---TDMDVIAPMREMNLTREWEI-DYAKEHGIPVEVTKS--------------------------------------------
>UniRef50_C7LPQ4(7-210:264) Putative uncharacterized protein n=1 Tax=Desulfomicrobium baculatum DSM 4028 RepID=C7LPQ4_DESBD  E=4e-10 s/c=0.33 id=17% cov=84%
-----VLWTGGWDSTFrVLYLVVVEKCPVQTFYIIDPFRWS----LVHEFKAMSNIKRTLKQKYPELSALLLPTLYFDKTDV--GENLHLSVCYDGLKERLGGQYEWLSIWADQFGLSEIELVIERSDSVVGCRSVIANYLSEDEKGYRGIDAKFKgtpvydlfhyFAFAITDIYKVDMRRIAAEHD-FADILNLSWFCHRPtFFSKPCGTCNPCK---------------------------
>UniRef50_C0CQN5(36-180:273) Putative uncharacterized protein n=1 Tax=Blautia hydrogenotrophica DSM 10507 RepID=C0CQN5_9FIRM  E=5e-10 s/c=0.46 id=32% cov=26%
-------FSGGVDSAYLLYAAMKNHCQLTAYFIKTPFQPQFELDDALRLAEELSA-PLKVLSLDIL---------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6UPN1(39-211:299) Thiamine biosynthesis protein n=6 Tax=Methanococcus RepID=A6UPN1_METVS  E=1e-09 s/c=0.38 id=32% cov=24%
-EKIVVMLSGGKDSAVSLAIAKSLGLNVHlCVHFLHDWSWNISTDEAKKLADRFNVK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C6A5B5(27-181:254) NH(3)-dependent NAD(+) synthetase n=7 Tax=Thermococcaceae RepID=NADE_THESM  E=1e-09 s/c=0.42 id=23% cov=63%
-KGVILGISGGVDSATVAYLAARAigKEKVLGLVMPYHI--NRDVEDALLVCNNLGINYKVINIKSIVNEF---------EKNLDFELNNVSRGNIMSRTRMILLYAHANSK------NYLVLGTS---------NRSEFLTGYFTKWGDSASD----YAPLINLYKTEVWNIARILG-------------------------------------------------------
>UniRef50_D1J9C4(232-343:711) Putative uncharacterized protein n=1 Tax=uncultured archaeon RepID=D1J9C4_9ARCH  E=3e-09 s/c=0.57 id=29% cov=24%
-----VLFSGGLDSTLIAYLCKELGADFVCYTVAVeepGMKDAEDLDYAKQIAADLGLKLKLI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_UPI000038E106(18-176:413) argininosuccinate synthase n=1 Tax=Ferroplasma acidarmanus fer1 RepID=UPI000038E106  E=6e-09 s/c=0.40 id=30% cov=26%
MDKVLLLYSGGLDTSVMAKWIqKEMKKEVVTLTLNIG---NSNLQKIKEKALGLGVSDAIVLDV------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q9SZX3(97-211:494) Argininosuccinate synthase, chloroplastic n=278 Tax=cellular organisms RepID=ASSY_ARATH  E=7e-09 s/c=0.55 id=31% cov=27%
-KKVVLAYSGGLDTSVIVPWLKENyGCEVVCFTADVGQ-GIKELEGLEQKAKASGASQLVVKDL------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q0G0X3(39-197:458) PP-loop family protein n=1 Tax=Fulvimarina pelagi HTCC2506 RepID=Q0G0X3_9RHIZ  E=1e-08 s/c=0.39 id=35% cov=23%
--RLLIAVSGGPDSLALLVLASRLPnlvFAVHAATVNHGLRREADMEAAhvAEVSQRLGV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A3SLP8(13-219:228) Putative uncharacterized protein n=1 Tax=Roseovarius nubinhibens ISM RepID=A3SLP8_9RHOB  E=2e-08 s/c=0.30 id=21% cov=84%
----LIMLSGGIDSTFLLAQALRETEDLVLVHhvhlINLEGRHRAEAHACKKIVEYCRRNYRdFVYTESTVDRSGLYAMGYDVITVASEAGIAATNHLLETGG-MADFWMLGFNLEEAHDAeeenDEVGLSASGDQAAQRPATNRLPYILAAIAATCFPNAPPKYLRPILQ-PKRELMDyMGQDLVDLC------WTCRRPVRTDQgfheCGECKTCKL--------------------------
>UniRef50_UPI0000E46BAB(156-273:433) PREDICTED: hypothetical protein n=1 Tax=Strongylocentrotus purpuratus RepID=UPI0000E46BAB  E=4e-08 s/c=0.52 id=23% cov=26%
-RRIGCMLSGGLDSSLVSSLvmkaMVKDGFDYPLQTFSIGMKGSPDVVAARKVASHIGSEHHEI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B3E8G9(18-78:261) ExsB family protein n=1 Tax=Geobacter lovleyi SZ RepID=B3E8G9_GEOLS  E=5e-08 s/c=0.99 id=36% cov=24%
-----VAFSGGVDSTLLLKVAHDtLGDRCCAITIDAPYHFRQEQDDATRFARQIGVRHLII---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q5UQE1(256-313:550) Probable asparagine synthetase [glutamine-hydrolyzing] n=1 Tax=Acanthamoeba polyphaga mimivirus RepID=ASNS_MIMIV  E=1e-07 s/c=1.02 id=25% cov=26%
------LLSGGLDSSLIVAIATRLLGPTNIVCFSVGFEGSPDVAAAREVVKFLGIKNHHIVPFS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A0RRA8(254-401:600) Asparagine synthase (Glutamine-hydrolyzing) n=2 Tax=Campylobacter fetus RepID=A0RRA8_CAMFF  E=1e-07 s/c=0.40 id=22% cov=22%
-------LSGGLDSSVTATVLAKNGFKFKTISIGFESDKFNESDYAAAVAKNLGLE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q701W8(40-193:267) Putative asparagine synthetase n=1 Tax=uncultured crenarchaeote RepID=Q701W8_9CREN  E=2e-07 s/c=0.38 id=27% cov=24%
-------FSGGIDSTLLAKICKNMNIDTTLLTI--GFPDSNDIEFSKTISRKINMN-HKVLEID-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A7H8W2(43-211:303) tRNA 2-thiocytidine biosynthesis protein ttcA n=3 Tax=Myxococcales RepID=TTCA_ANADF  E=2e-07 s/c=0.35 id=20% cov=47%
--RIMVAVSGGKDSYTLLHVLMRLrerapiDFDLVAVNLDQGQPGYP-AEIVERHFQAVGVPHRML-------------YADTYSIVRRLVPEGKTTCPVCSRLRRGVLYNAAA----EMGCTKIALGHHRDD--------------------------------------------------------------------------------------------------------
>UniRef50_B2KF01(27-200:241) tRNA(Ile)-lysidine synthetase n=1 Tax=Elusimicrobium minutum Pei191 RepID=B2KF01_ELUMP  E=2e-07 s/c=0.33 id=24% cov=24%
--KVLVGVSGGADSVCLLHfltqLAQKKRFRVYACHINHSLRenAKKDELFTKKLCEQLGVE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D0GMM0(25-176:307) tRNA(Ile)-lysidine synthase n=1 Tax=Leptotrichia goodfellowii F0264 RepID=D0GMM0_9FUSO  E=3e-07 s/c=0.38 id=18% cov=46%
--KILLAFSGGPDSVFLYRILSffqeKYSLELALMYVNHNLRHdvEKDLEFVKRFSEENGVQLYT-------------------ESVNVNDYSSKNRKSTELAARELRYSAL-TEKADDVGYDKIATGHNLDD--------------------------------------------------------------------------------------------------------
>UniRef50_Q2WB66(257-335:627) Asparagine synthase n=3 Tax=Magnetospirillum RepID=Q2WB66_MAGSA   E=3e-07 s/c=0.73 id=26% cov=22%
-----CFLSGGIDSSVVAALMAEgAADPVRTFTMTFDEVHYDEREAAAQVAAHVG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_P00966(7-120:412) Argininosuccinate synthase n=123 Tax=cellular organisms RepID=ASSY_HUMAN  E=4e-07 s/c=0.50 id=35% cov=26%
---VVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQK--EDFEEARKKALKLGAKKVFIEDVS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A3I1Z0(260-401:622) Asparagine synthase (Glutamine-hydrolysing) n=1 Tax=Algoriphagus sp. PR1 RepID=A3I1Z0_9SPHI  E=4e-07 s/c=0.40 id=26% cov=25%
-------LSSGIDSSLITAIAKELKPDILAVTMATAESHSDESPAATEFAKKLDIKQ-EIIPVD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A8G8L6(261-313:610) Asparagine synthase (Glutamine-hydrolyzing) n=1 Tax=Serratia proteamaculans 568 RepID=A8G8L6_SERP5  E=9e-07 s/c=1.06 id=30% cov=23%
------MLSGGLDSSLITAIACRQGrRELKTFAVGFNESAFSELDYSRRLAKDLGTEHH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C1SG70(11-95:223) ExsB protein n=1 Tax=Denitrovibrio acetiphilus DSM 12809 RepID=C1SG70_9BACT  E=9e-07 s/c=0.66 id=33% cov=23%
---AIVALSGGADSAAVLMLAAEHigKNNVLAVTCVNQHFFESELENAAKIAAILGVR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C1TPL0(20-169:264) PP-loop superfamily ATP-utilizing enzyme n=1 Tax=Dethiosulfovibrio peptidovorans DSM 11002 RepID=C1TPL0_9BACT  E=1e-06 s/c=0.37 id=33% cov=23%
---VLVSFSGGVDSSAILALLagiMPDG-TFHSVLFDSFLHPEKERERAVSLCRDLGV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C7MEA1(179-240:526) Asparagine synthase (Glutamine-hydrolyzing) n=1 Tax=Brachybacterium faecium DSM 4810 RepID=C7MEA1_BRAFD  E=1e-06 s/c=0.89 id=24% cov=25%
--RVIALpLSAGLDSRLLAALLARDGY-PNVLTVTYGLPGNAEARASSRIAESLGLPWRQV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q2NSV5(43-204:353) tRNA 2-thiocytidine biosynthesis protein ttcA n=347 Tax=Bacteria RepID=TTCA_SODGM  E=2e-06 s/c=0.34 id=24% cov=47%
--RIMVCLSGGKDSYTLLEILRNLqqsapvNFSLVAVNLDQKQPGFPAHVLPEYLAAQ-GVEYHIVTE-------------DTYHIVKDKIPEGKTTCSLCSRLRRGILYRTAT----ELGATRIALGHHQDD--------------------------------------------------------------------------------------------------------
>UniRef50_B0KAB0(222-336:503) Asparagine synthase (Glutamine-hydrolyzing) n=7 Tax=Clostridia RepID=B0KAB0_THEP3  E=2e-06 s/c=0.47 id=27% cov=24%
-----VFLSGGLDSSLIAAIAAKYKNPLH--SFAVGVEGSNDLKNARVVADYVGTIHHEFI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1PIW9(258-386:615) Asparagine synthase n=2 Tax=Clostridiales RepID=D1PIW9_9FIRM   E=3e-06 s/c=0.42 id=27% cov=22%
-----CFLSGGVDSSLTACKAARQQSHLQCFSVGYAEEAYSELPAARQAAEALEV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6GKC6(34-196:287) PP-loop n=1 Tax=Plesiocystis pacifica SIR-1 RepID=A6GKC6_9DELT   E=3e-06 s/c=0.33 id=17% cov=47%
---VMVAVSGGKDSYTLLDLLVLArsrapiDFQITAVHLDQVQPG-------------YDGSPLRTWLEDFRGRTKVDFeiaQEDTYTTVVDLTPPGKAYCAVCSRLRRGVLYNV----AERLGCNKIALGHHRDDA-------------------------------------------------------------------------------------------------------
>UniRef50_C5NVJ2(12-74:438) Putative bifunctional protein TilS/hprT n=1 Tax=Gemella haemolysans ATCC 10379 RepID=C5NVJ2_9BACL  E=3e-06 s/c=0.86 id=21% cov=23%
-------LSGGVDSIALFHLLvteyKESYKELVAFHINHGLREQSyeEAEFVENFVKNYNVKFYK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B2RK58(189-338:533) Putative uncharacterized protein n=2 Tax=Porphyromonas gingivalis RepID=B2RK58_PORG3  E=4e-06 s/c=0.36 id=26% cov=23%
-RSAILPLSGGFDSRMIAYMLHRLKY-PHVYCISYGKEENPDSLKAAKVADKLG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B5HJ99(260-350:644) Asparagine synthetase n=8 Tax=Streptomyces RepID=B5HJ99_STRPR   E=4e-06 s/c=0.59 id=27% cov=23%
-------LSGGLDSSYLTALAARHRPGISAYTI--GFRAEdakfeampDDLRYARQVAERFGVDLHEI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A3HV72(250-392:591) Probable asparagine synthetase (Glutamine-hydrolyzing) n=1 Tax=Algoriphagus sp. PR1 RepID=A3HV72_9SPHI  E=4e-06 s/c=0.38 id=34% cov=24%
-----MMMSGGADSSLLyATWYQQTGVELPAFTLQVEQKYRKkysDADAARELIKKVPAQHHLV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q8U2P1(199-261:536) Putative uncharacterized protein n=1 Tax=Pyrococcus furiosus RepID=Q8U2P1_PYRFU  E=5e-06 s/c=0.86 id=38% cov=21%
----VIPLSGGYDSRAIATMLKKNGYEnVILYT--YGKPDSTEVRVAREVAKNL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q9YAI1(41-197:286) Probable NH(3)-dependent NAD(+) synthetase n=1 Tax=Aeropyrum pernix RepID=NADE_AERPE  E=5e-06 s/c=0.34 id=26% cov=30%
----VLGVSGGVDSSLALALAVDAvgSGRVTALIMpDREVTPERDVEDALRLVRSFGVE-HAVIDISPIVMVYISAL-------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C5U696(246-311:495) Asparagine synthase (Glutamine-hydrolyzing) n=1 Tax=Methanocaldococcus infernus ME RepID=C5U696_9EURY  E=6e-06 s/c=0.81 id=23% cov=23%
--RVAIICSGGLDSSLVAALSVKYNRNVKLYSV--GLEGSEDLKYSQMLADHLGVE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A9IYI2(19-153:495) tRNA(Ile)-lysidine synthase n=4 Tax=Bartonella RepID=TILS_BART1   E=6e-06 s/c=0.40 id=25% cov=22%
-RRVILAVSGGSDSLALMFLVKEYLEtllippEIIAVTVDHQLRkeSAREAEIVAEICR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A7GZE7(17-170:330) PP-loop family n=2 Tax=Campylobacter RepID=A7GZE7_CAMC5   E=6e-06 s/c=0.35 id=29% cov=23%
--KNLLAFSHGVDSTALFYILNDAGVGFDIAIVDYNERAqsKDEVASARALAAKF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q1GE22(23-176:430) tRNA(Ile)-lysidine synthetase-like protein n=2 Tax=Ruegeria RepID=Q1GE22_SILST  E=6e-06 s/c=0.35 id=30% cov=22%
-----VAVSGGSDSValmhVLATMARAEDTALAVATVDHGLRPEsrREAEFVAQQAHDLG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C8R1X4(49-246:291) PP-loop domain protein n=1 Tax=Desulfurivibrio alkaliphilus AHT2 RepID=C8R1X4_9DELT  E=7e-06 s/c=0.27 id=23% cov=52%
--RVMIAVSGGIDSLVLcrLLDLWRRkapiHYELLPVHLDMGFagyRPRPGLygggplppEAGALQADGLlpplpGTGAAVQEQLEKLGLPYLIEETTYGPEALAAEEGKNGCYHCSSRRRNRLF-----ALAREHNCNKLALGHHQED--------------------------------------------------------------------------------------------------------
>UniRef50_Q7M7N7(250-307:604) WBFR PROTEIN n=1 Tax=Wolinella succinogenes RepID=Q7M7N7_WOLSU   E=9e-06 s/c=0.91 id=26% cov=23%
-------LSGGIDSSLISALYARLSpCSIETFSIGYdEYKHYDELPYAREVASHIGSIHHE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A9AVN7(262-316:622) Asparagine synthase (Glutamine-hydrolyzing) n=1 Tax=Herpetosiphon aurantiacus ATCC 23779 RepID=A9AVN7_HERA2  E=9e-06 s/c=0.96 id=26% cov=23%
-------LSGGLDSSIIVGLMQRLGAAPIN-TFSVGFEHAgfNELPDAALVAQHFGTKHHEL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D2LP87(44-153:288) PP-loop domain protein n=3 Tax=Aciduliprofundum boonei T469 RepID=D2LP87_9EURY  E=9e-06 s/c=0.48 id=16% cov=24%
--KIAIALSGGKDSMVLLHYFAERDYDIFGYFINLgiGEHSDKMEKLVRNACKEYGVE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_UPI0001AEBAFE(261-327:634) asparagine synthase (glutamine-hydrolyzing) n=1 Tax=Alteromonas macleodii ATCC 27126 RepID=UPI0001AEBAFE  E=9e-06 s/c=0.79 id=23% cov=24%
-----IFLSGGIDSSAVVGLLADRVKEPLkTFSIAYDFgKNYDETQYARMVAERFGTDHHEL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q01XN2(262-340:631) Asparagine synthase (Glutamine-hydrolyzing) n=1 Tax=Candidatus Solibacter usitatus Ellin6076 RepID=Q01XN2_SOLUE  E=1e-05 s/c=0.67 id=25% cov=24%
-------LSGGIDsSSIVASMAMQSREPIKTFSIGFEESEFNELPYAAMVARKYGADHHEIV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A5PEC9(25-181:325) ATPase n=1 Tax=Erythrobacter sp. SD-21 RepID=A5PEC9_9SPHN   E=1e-05 s/c=0.34 id=27% cov=41%
-------FSGGPDSLALLLLAVEALPgSVEAATVDHGLRAESaeEARNAARICEALGMPHETL-----------------SVTIPHGNVQAE--------ARHARYEALAE-WAERRSLDYIATAHHADD--------------------------------------------------------------------------------------------------------
>UniRef50_A8RFA7(11-161:404) Putative uncharacterized protein n=1 Tax=Eubacterium dolichum DSM 3991 RepID=A8RFA7_9FIRM  E=1e-05 s/c=0.35 id=18% cov=21%
-------VSGGPDSMALLDMCRRHGVSMVVAHVNYQKResAARDMQIVQDYCKQYGI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q1IAN5(214-271:596) Putative asparagine synthetase n=1 Tax=Pseudomonas entomophila L48 RepID=Q1IAN5_PSEE4  E=1e-05 s/c=0.89 id=26% cov=23%
--------SSGFDSTLGAALLQKtLGKPIHTFTAGFQGMHCNEAPDAAAIARHLGTLHHEI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A9I748(278-332:642) Asparagine synthase n=10 Tax=Proteobacteria RepID=A9I748_BORPD   E=2e-05 s/c=0.94 id=26% cov=22%
-------LSGGIDSSTIVALMQAQSRQpVRTFAIGFHEKGYNEAEHAKAVARHLGTE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q15WL8(262-360:634) Asparagine synthase (Glutamine-hydrolyzing) n=8 Tax=Proteobacteria RepID=Q15WL8_PSEA6  E=2e-05 s/c=0.52 id=23% cov=23%
-------LSGGIDSSgVVAMMALNSDKPVKTCSIGFDEKRFNETEFAQIVADQYKTEHHE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q01Z46(261-367:639) Asparagine synthase (Glutamine-hydrolyzing) n=2 Tax=Acidobacteria RepID=Q01Z46_SOLUE  E=2e-05 s/c=0.48 id=29% cov=23%
--------SGGLDSSAILHYAAAQtAGRLKTFSVSFEGRSFDESRYFREIAQVYGTDHHE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A1RWI3(89-162:353) Phosphoadenosine phosphosulfate reductase n=1 Tax=Thermofilum pendens Hrk 5 RepID=A1RWI3_THEPD  E=3e-05 s/c=0.69 id=30% cov=23%
-------LSGGKDSTANLYLLTKLqeivGFKVTAVYVHMPYLEPVEnIAFAEKVASRLGVDLRIV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A0L574(264-340:630) Asparagine synthase (Glutamine-hydrolyzing) n=1 Tax=Magnetococcus sp. MC-1 RepID=A0L574_MAGSM  E=3e-05 s/c=0.66 id=24% cov=23%
-------LSGGVDSSLITALLAKQSQTPLqALTVAFTGSREDEAPHARAVAQHLGVQQQLL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B1GZK6(22-140:321) tRNA(Ile)-lysidine synthase n=1 Tax=uncultured Termite group 1 bacterium phylotype Rs-D17 RepID=B1GZK6_UNCTG  E=4e-05 s/c=0.43 id=24% cov=23%
--KIILSVSGGMDSMCMLHlfwrLAKKMDIVFLAVNFNHNLRKEsvKEAETVKNLSAEFGI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q12VP2(257-340:634) Asparagine synthetase (Glutamine-hydrolyzing) n=2 Tax=cellular organisms RepID=Q12VP2_METBU  E=8e-05 s/c=0.59 id=26% cov=27%
-------LSGGIDSGIVTGLMSKMVDEpIETFSVGFGERGEiGELSQAQEAADFFGTNHHeIIVDQGAFKQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1B558(248-392:596) Asparagine synthase (Glutamine-hydrolyzing) n=1 Tax=Sulfurospirillum deleyianum DSM 6946 RepID=D1B558_SULD5  E=9e-05 s/c=0.34 id=22% cov=24%
------LLSGGIDSSlVSAIYTKVSGKKINTFSIGYDEHlHYDELTQAKEASVHIGSQHHEL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A1WWZ7(23-78:440) tRNA(Ile)-lysidine synthetase n=1 Tax=Halorhodospira halophila SL1 RepID=A1WWZ7_HALHL  E=0.0001 s/c=0.88 id=29% cov=22%
-----VAFSGGRDSTALLHALAEVRDRlpapLAAVHIDHGLHPESARwaEACESVCERLGV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_P54420(263-312:632) Asparagine synthetase [glutamine-hydrolyzing] 1 n=101 Tax=Bacteria RepID=ASNB_BACSU  E=0.0001 s/c=0.98 id=30% cov=22%
-------LSGGIDSSFIVSVAKEFHPSLKTFSVGFEQQGFSEVDVAKETAAALGIE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B9E8U3(1-165:403) Putative uncharacterized protein n=1 Tax=Macrococcus caseolyticus JCSC5402 RepID=B9E8U3_MACCJ  E=0.0001 s/c=0.30 id=21% cov=23%
-----VAVSGGVDSMVLLDKIRRSGCfkQLYVLHVNHQLRdvSREEQEMIQRYCTSYGIE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A3SIU9(2-156:396) PP-loop family protein n=1 Tax=Roseovarius nubinhibens ISM RepID=A3SIU9_9RHOB  E=0.0001 s/c=0.32 id=37% cov=23%
-----VAVSGGSDSTALLLGLKDwaQGREVslYAVTVDHGLRaaAAHEAEAVAQLCAELALPHH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q186I9(266-345:624) Asparagine synthetase n=5 Tax=Clostridium difficile RepID=Q186I9_CLOD6  E=0.0001 s/c=0.61 id=28% cov=22%
-------LSGGIDSSIITTVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1C1U5(28-79:468) tRNA(Ile)-lysidine synthetase n=1 Tax=Sphaerobacter thermophilus DSM 20745 RepID=D1C1U5_SPHTD  E=0.0002 s/c=0.93 id=25% cov=21%
---VLIGFSGGADSLALtaslqAIHAAGRGPRPLALHVNHRLRPEADADAERAVA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B3ZRE3(197-356:545) Putative uncharacterized protein n=1 Tax=Bacillus cereus 03BB108 RepID=B3ZRE3_BACCE  E=0.0002 s/c=0.30 id=25% cov=22%
----LIPLSGGLDSRLLACLAQSE--RLNFRSLVFGPKHSNEVTIAKEVSRKLNIK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C8Q8D7(245-317:482) Asparagine synthase n=1 Tax=Pantoea sp. At-9b RepID=C8Q8D7_9ENTR   E=0.0002 s/c=0.66 id=22% cov=22%
-------LSGGLDSSLITALASRYFDQIFTYSI--GTEFSNEFEFSKIVSDSLNTNHH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_UPI0001745306(266-341:644) Asparagine synthase, glutamine-hydrolyzing n=1 Tax=Verrucomicrobium spinosum DSM 4136 RepID=UPI0001745306  E=0.0002 s/c=0.63 id=22% cov=23%
-------LSAGVDSSLTVAAMTKHSSNINTYSVGFNS-PVDETPAARETAAFLGTKHHEII--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_UPI0001746B50(262-320:650) asparagine synthase (glutamine-hydrolyzing) n=1 Tax=Verrucomicrobium spinosum DSM 4136 RepID=UPI0001746B50  E=0.0002 s/c=0.82 id=28% cov=22%
-----VFLSGGLDSTLMVALMRQHGLtDIQAFSIGYEENAGvpDESDAAEKTAEFYG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q58516(260-382:541) Putative asparagine synthetase [glutamine-hydrolyzing] 1 n=10 Tax=Methanococcales RepID=ASNH1_METJA  E=0.0003 s/c=0.39 id=27% cov=23%
--KVGIICSGGVDSSLIAKLA-SLYCEVILYAV--GTENSEDLIYAERLAKDLNLK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B7J9F8(258-339:632) Asparagine synthase (Glutamine-hydrolyzing) n=1 Tax=Acidithiobacillus ferrooxidans ATCC 23270 RepID=B7J9F8_ACIF2  E=0.0003 s/c=0.58 id=31% cov=23%
-------LSGGIDSGLVTSMMAQEG-TVETVTLGFAEAAFDERVYARQVAARWGLRTHE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C6CGN7(241-295:503) Asparagine synthase n=4 Tax=Enterobacteriaceae RepID=C6CGN7_DICZE   E=0.0004 s/c=0.86 id=26% cov=22%
-------LSGGLDSSLVTAMASQFFQHIKTWSI--GTEISNEFEYSQMVADALGTEHH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A1TJF6(7-63:319) Phosphoadenosine phosphosulfate reductase n=2 Tax=Proteobacteria RepID=A1TJF6_ACIAC  E=0.0006 s/c=0.82 id=29% cov=22%
----LVNVSGGKDSTATYLLALESGRDFRAVFADTGNEHELTYEFVQRLPERTG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B7KM32(265-324:627) Asparagine synthase (Glutamine-hydrolyzing) n=1 Tax=Cyanothece sp. PCC 7424 RepID=B7KM32_CYAP7  E=0.0007 s/c=0.78 id=27% cov=21%
-----VFLSGGIDSSTLVGLARQASlEDIHTVSIIFDEPEYNELSYISQVAERF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_UPI0001C171C7(58-276:282) ExsB n=2 Tax=Nostocaceae RepID=UPI0001C171C7   E=1e-53 s/c=0.96 id=38% cov=92%
--KAVILLSGGLDSSTVLYQARADGYECYVISFDYHQRHRRELQSAISIAQSLEVVEHQLVTFD-LRSWGGSALTDNSIPVPQNRPldqMSGSIPITYVPARNTIFLSFALAYAEAIRAERVYIGVNALDYSGYPDCRPDYIHAMQEVFRLGTkqgreGKRIDIVAPLINLTKSQIIQLG---NLLGVPWELTWSCYSGDQ-QPCGVCDSCQLRWAAFHELGLEDP-------------
>UniRef50_B6CWJ6(13-230:238) ToyM n=3 Tax=Bacteria RepID=B6CWJ6_STRRM   E=1e-48 s/c=0.89 id=35% cov=93%
---AVVVLSGGMDSTTLLAHYAMLRYRLTAVTVDYGQRHRREIDAARTIAGHYGAEHHVVDLSGIGVLLGGSALTDSEVDVPSGHYAEESMRATVVPNRNAILANVAVGAAVARQAGIVALGMHAGDHFVYPDCRPAFVEALDGLVRVANEGfaTPRVEAPFIHWSKTDI---ARYGSRLEAPLDKSWSCYRGGE-LHCGTCGTCYERREAFRDADVPDPTEY----------
>UniRef50_C4Z7K4(2-226:227) Queuosine biosynthesis protein QueC n=5 Tax=Bacteria RepID=C4Z7K4_EUBE2  E=2e-48 s/c=0.86 id=31% cov=93%
--KALVLSSGGVDSTTALALAVSRYgkDNVIALSVSYGQKHDKEIQAAKAVSAFYGVEQLFLDLSKIFQYSNCSLLQQSTEEIPEESYarqiektEGEKPVSTYVPFRNGLFLSSAASIALSKDCSVILYGAHADDSAGfaYPDCSPMFNDAMNQAIFEGSGHQLKVEAPFVNMTKAEVVKMGL---ELNAPYELTWSCYEG-KDVPCGKCGTCIDRAAAFAANGVSDPAI-----------
>UniRef50_D1PYH8(26-241:242) Transcription regulator ExsB n=5 Tax=Prevotella RepID=D1PYH8_9BACT   E=8e-47 s/c=0.88 id=29% cov=93%
-RDAIIIVSGGMDSITMLYEFQDRIA--LGLSFDYGSNHnAREIPYAEMHCKRLGI-PHIIIPLDFMSRYFKSSLLEGADAIPEGDYNEVGMKSTVVPFRNGIMLSIAAGMAESQNLKYIMMANHSGDHIIYPDCRPEFIRAMSKATQTGTFPGIKILAPYTDITKGDI---ACRGKALGLDYTETWSCYKGGE-RHCGKCGTCLERIAALKDAGIKDLTEY----------
>UniRef50_Q981C9(243-461:464) 7-cyano-7-deazaguanine synthase n=13 Tax=Thermoprotei RepID=QUEC_SULSO  E=3e-46 s/c=0.85 id=26% cov=89%
--RVLVVASGGLDSTVAATKLLREGHEVTLIHFNYHHKAeEKEREAVRKIAEYLQIPLLEIN-TDLFKIIGHATLIKGGGEIVKDRKGEEGAEfaHEWVPARNLIFFSVSLAIAEAYGYDAIASGINLEEAGAYPDNEMEFIRMLNKLspYATGPNKRIEILMPVGNLVKHEIVKLGYEIG---APLHLTWSCYEGGQ-KHCGKCGPCYMRKMAFR--------------------
>UniRef50_A5ULR3(4-225:227) 7-cyano-7-deazaguanine synthase n=5 Tax=Methanobacteriaceae RepID=QUEC_METS3  E=5e-46 s/c=0.84 id=31% cov=93%
-KKAITVLSGGLDSCVATCVYAED-YEIHGITFNYGQKSfKQELKASEEICKKMGFT-HEVIDLPWLNKISNSSLTSDNeiptlthEELDDLDICEDTASSVWVPGRNIVFTSIATSYAESIGAEIIIVGWDKEEAATFPDNSKEFLESFNNMLNVGSPQNIEIKAPAIDLNKDEIVKLGDEI---KAPMELSYSCYTGHE-KHCGVCESCMRRKRAFKLADVKDPSEY----------
>UniRef50_D2RGV6(1-212:233) ExsB protein n=2 Tax=Archaeoglobaceae RepID=D2RGV6_ARCPR   E=1e-45 s/c=0.87 id=31% cov=90%
--------SGGIDSSTLLWYLMKRYDEIYVITYIYGQRHAREVEHAKMIVEKAREKakiHHEIADISCIQRLIAKGALTGNEEVPEGFYTDESQKKTIVPNRNMILLAIAVGYAVKVGEREVYYAAHKSDYATYPDCRKEFVKALDTAVYLATIfDPVVIKAPFVDMTKADIVKLGLK---LGVPYELTWSCYRGEE-RPCLRCGTCLERTEAFLINGVKDPA------------
>UniRef50_A6DLD5(1-222:226) ExsB protein n=1 Tax=Lentisphaera araneosa HTCC2155 RepID=A6DLD5_9BACT  E=1e-45 s/c=0.83 id=34% cov=93%
MKKAAVLISGGLDSTTLLHHVIKSlgYDEVYALSFDYGQKHSRELIVAKAQCDSLPeVKEHNVLDISYMGDFLGSSsaLVKGGVEVPDLKDIAEGdldQPVTYVPNRNMMLLSIAASFAESRDCRQLYYGAQAQDEYGYWDCTESFLARMNDVFSLNRRTGVHVEAPFVNMSKGHVAKIGLA---LGIDYAQTWTCYRGG-DKPCEVCPSCVERALAFKECGIDDP-------------
>UniRef50_Q6ARX9(1-217:219) 7-cyano-7-deazaguanine synthase n=2 Tax=Bacteria RepID=QUEC_DESPS   E=3e-45 s/c=0.85 id=35% cov=90%
MVDSIIVLSGGMDSAVLLAQTLKEGKTAQAISFDYGSKHNdRELPMAVGLCEEFAIK-HQIIKLPFIGELFSSSLLTGGEEIPDGAYGQENMKSTVVPFRNGIMLAIAAGYAESVQAGEVLLGSHSGDHHIYPDCRPEFNNAFAEAVNLGTDGQVAIRFPFSEMTKRDIGDLGR---TLDLDFAKTWTCYKGGE-LHCGVCAACDERKEALRH-------------------
>UniRef50_Q5JHU5(1-234:239) 7-cyano-7-deazaguanine synthase n=6 Tax=Thermococcus RepID=QUEC_PYRKO  E=9e-45 s/c=0.78 id=29% cov=95%
MKRAVVLFSGGLDSTACLYWAKKNYDEVIMLTVNYGSNEEKVTNKVAEfFSKELDVPLKIVRldFLEEFSKLRGTTLVGGETPkvtgeeLENIEVAQETAKSVWVPARNVVLIAVAASLLDALGGGDIVVGFNAEEGATFPDNTPEFVEKMNEMLKYGTMAEVRVVAPLINLDKRGI---AKLLKELGAKYEYSNSCYMPkgftedGKPIHCGECESCVRRHRGLIEGIGEDKTVYA---------
>UniRef50_A5A3S4(4-234:301) BcepGomrgp35 n=1 Tax=Burkholderia phage BcepGomr RepID=A5A3S4_9CAUD   E=1e-43 s/c=0.77 id=46% cov=93%
-KTAVIVFSGGQDSTTILGKAIAEGYRVFPIAFTYGQKHAIELEQAAKIVDHFGLAGLKIVDLSALGEVTTSALIGTDGDVNKPSDANPSLPASFVPNRNAAFLTLAHAYAQQVGADELWTGVCMTDYSGYPDCRDSFINALAATLNIGYDTSITIKTPLMYIDKAETFRMAELAGCLDVVIEMSHTCYNGVRsngevptnpsegggffdwGHGCGECPACKLRAGGWREYL-----------------
>UniRef50_C0WAE7(3-229:233) Archaeosine biosynthesis protein queC n=3 Tax=Bacteria RepID=C0WAE7_9FIRM  E=5e-42 s/c=0.76 id=29% cov=93%
-KKALVLSSGGVDSTTCVSVAvHELGREnVATVSIFYGQKHRKELDAAQKVADFYHVPHYELDLSKIFQYSNCSLLSHSTEEIIHESYEdqiaqnGEGKVSTYVPFRNGLMLSAVASLAMSLfekDDVDIYLGAHADDAAGnaYADCSEAFTDAMGKAISIGTYEQCHLVAPFVEVNKAGIVKKGL---ELGTPYELTWSCYEGG-DRPCGTCGTCIDRARAFAANGVPDPA------------
>UniRef50_B3T674(10-231:233) Putative ExsB n=1 Tax=uncultured marine crenarchaeote HF4000_ANIW141O9 RepID=B3T674_9ARCH  E=3e-40 s/c=0.75 id=32% cov=93%
MKKAVVVFSGGIDSvSTCTYL--KQKYELYGISFLYGQKANQEIKKAKSFAKILGLKEHKVVDINFMKKLYGDTNALTSSKKKIPS---KFNYSVVVPIRNGIFLSIATAWAFSINASLVAYGAHMGD-KNYPDCRPAFSKKIEFAFNQGEIDGIKsgirkriqIWSPYKAKL-SKKQLLKKGYDTLGDKIFNTWSCYKNGKV-QCGKCESCNNRKAVFLEAGIEDKTPY----------
>UniRef50_C6XGK1(11-237:240) ExsB protein n=9 Tax=Bacteria RepID=C6XGK1_LIBAP   E=5e-39 s/c=0.72 id=42% cov=89%
---ALLLFSGGQDSSTCLSWALDRFDRVETLSFDYGQRNKVELEC------RLCVRKKIVELMPKWKDSLGEDHILPLAILGDIShssltknvamkIQDNNLPNTFVPGRNIIFLVFAATLAYRLGITNIVIGVCETDYSGYPDCRHDTIRAIETAINLGMESHVTVHTPLMWLKKYETWKLAQDIGgqdLVNLILEESHTCYLGKRdkryewGYGCNSCPACYLRQKGWMEFK-----------------
>UniRef50_B9ZKA9(15-215:217) ExsB family protein n=1 Tax=Thioalkalivibrio sp. K90mix RepID=B9ZKA9_9GAMM  E=9e-33 s/c=0.71 id=23% cov=86%
----LLLLSGGIESSALLAQRHAQGRPLRALWVDYGQRnAERERAAIRALGADYGVDPVEMDLRALRQAF---------------AKRSEWVAHVPLPQRNLLVLALAINLAEHQGAGRILLALNREDQGHGPGSRPSFIGRLAALADE-LVPGLAIEAPLIAQSKADII---YTTDPLGIDWSRTWSCLL-AQSLHCGRCPQCQARRAAFASAGVPDPTDY----------
>UniRef50_B9M1I5(3-190:196) ExsB family protein n=4 Tax=Proteobacteria RepID=B9M1I5_GEOSF   E=5e-28 s/c=0.67 id=35% cov=81%
----VTLVSGGLDSTLIAKLAQEEGLIQHPLFVDYGQRARDqELAACRRGMSELGLPEPRVADLSGFGALIHSGLTDSSLDI---------VKDAFTPGRNMLFLLIAAAYAVQVKADAISIGLLHESTSLFPDQTSAFLRDAEVLIRRCMNRDIKLLAPLASFLKTDVVALAKLKR-----IGATYSCHTGNEET-CGTCIACRE--------------------------
>UniRef50_B0V938(149-366:442) Putative uncharacterized protein n=4 Tax=Acinetobacter baumannii RepID=B0V938_ACIBY  E=9e-26 s/c=0.55 id=18% cov=85%
--DSVCLFSGGLDSTIGAIDLKAQGKKSVLVSHAYPKDRQ---------------KQDHVYYDLQFDNARFQVL-------ANPRKVKEIPADVQMRTRSFNFIAFGALIATALsknhfsnKIIKLYIPENGlisinppltprrIGALSTRTTHPYFLQKLNILFK-NIGLPVEIENPYQYKTKGEMMLECKDQSSLKKIAATTVSCGKWKRsGMQCGKCLPCLIRRASFDKYQYKDLTQY----------
>UniRef50_Q9RZH7(136-351:423) Putative uncharacterized protein n=1 Tax=Deinococcus radiodurans RepID=Q9RZH7_DEIRA  E=1e-25 s/c=0.55 id=20% cov=83%
----VALLSGGLDSLVGMIDLVAEGHNPLAVS----QLVAGDAAKQREIATDLGRTTHL--------------QLNHAAECPTPGEDSQ-------RSRTLIFLAYAVLAATAttrfQQARAVPIYINengfialnppltpmRIGSLSTRTAHPVFLQQLQAVL-QAVGLNVALINPYALKTKGEMLTECANQTVLSRWASATTSCgrYRRFGYKHCGRCIPCQVRRAAFLAWGQPDRTEY----------
>UniRef50_Q8R5Z5(1-202:343) tRNA-specific 2-thiouridylase mnmA 2 n=12 Tax=Fusobacterium RepID=MNMA2_FUSNN  E=2e-25 s/c=0.58 id=21% cov=84%
MKKVVIGMSGGVDSSVSAYLLKEQGYEVIGITLNQHLEEnSKDIEDTKKVCDKLGIIHEVVNIRKDFENIVIKYFLEG--------YNSGKTPSPCIICDDEIKFKILFDIADKYNAEYVATGHyTSVEYSEVFSKyllksvHSIIKDQSYMLYRLSPDKLERLIFPLKDYSKQEIREIA-----LKIDLEVH------DKKDSQGVCFA----KEGYKEFLKEN--------------
>UniRef50_B5YCZ9(4-194:345) tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase n=2 Tax=Dictyoglomus RepID=B5YCZ9_DICT6  E=9e-22 s/c=0.55 id=21% cov=71%
--KVAVGMSGGVDSSTTAYLLKKEGYEVIGLTMNIAYSDS--IKDAEKIAKYLNIPHFYVDLRKEFEEQIIKYFID--------SYKSGYTPNPCTFCNRIIKFGLLLKKAQELGAEYLATGHyvrkvWDEEKKVFLLKRAKDLKK-DQSYFLAYLTQEQIeksLFPLGDLTKNEVRKLAEEIG-------------------------------------------------------
>UniRef50_B9L3Q7(182-337:407) Thiamine biosynthesis/tRNA modification protein ThiI n=2 Tax=Thermomicrobia (class) RepID=B9L3Q7_THERP  E=4e-20 s/c=0.64 id=25% cov=67%
--RVVALLSGGFDSPVAAYRLMKRGCFVTFVHFHaYPYVRPISIEKAVELARHL----------SRFQPPKNRLIVVPIGDAQRVIALAAEPSLRVVLYRR-LMLRIATAIAHEEGAGALVTGESLGQVAS---------QTLENMRAIGAVTDLPLLRPLVGNNKDEIIAEAVRIG-------------------------------------------------------
>UniRef50_Q5NVV1(182-349:391) Thiamine biosynthesis protein (ATP pyrophosphatase) n=3 Tax=Archaea RepID=Q5NVV1_9ARCH  E=6e-20 s/c=0.59 id=18% cov=68%
--KMVALISGGIDSPVAAWLMMKRGCEIIPLYMDNTPYLGEDAK-----AKTIDI----VRKLHEWAPGREMKMYIAPHGQPLREFLQKGNKKYTCVFCKHLMYKVARAIAEKEGAHGIITGSSLGQVASQTS---------ENMMAEAYDVDFPIYHPLIGLDKEEIMTIAKKIG-------------------------------------------------------
>UniRef50_Q5P5F5(141-360:457) Putative uncharacterized protein n=1 Tax=Aromatoleum aromaticum EbN1 RepID=Q5P5F5_AZOSE  E=2e-19 s/c=0.45 id=19% cov=87%
---AIIAYSDGMDSRAVAGLESSRLGR-------------------RLVRMRVGSKQHDVSKKERLRIPFTALPYSVKLE-------NGRNAENSARSRGFKFSVVSTMAAYLIDAPSVIVPESGqgalapvllpvGQGYEDYRNHPVFTALMARFFNALLGYKIQYRFPRLWMTKGETLREFVDVCGSEARWATTRSCWQqsrqvavSGERRQCGVCAACILRRLSVHAAGlneLPKTYVWESLKAAT---
>UniRef50_C6NX81(5-196:206) Archaeosine biosynthesis protein queC n=1 Tax=Acidithiobacillus caldus ATCC 51756 RepID=C6NX81_9GAMM  E=2e-19 s/c=0.51 id=23% cov=82%
-ERSLLLCSGGVESFTLTH-AFGTDSGLYLFFLDYGQRaAAEEWKRVQNLARNLRLERERFDLRDFGDAVGR---------------LRPQRYHVPTPHRNLLAVAAAANVAESLGRNTVVLGTTADDGRTDRNANRAFLSALAATLSSS---GLYLALPLAQYRKAAVIRLGQD---LGVPWEMSYSCIVGYEA-QCGRCPQCIRRREAFRE-------------------
>UniRef50_B5DNY9(2-211:387) GA22395 n=14 Tax=Neoptera RepID=B5DNY9_DROPS   E=3e-19 s/c=0.46 id=21% cov=81%
IRNIVVGMSGGVDSAVSAHLLRERGHRVMGVFMRNWDEHdeagrcsgEQDLKDAEWACQRLGIELRQVNYVKEYWTAVFSAFLDD--------YQQGLTPNPDILCNRHIKFDLFHRHAlDKLGYDAVATGHYARNSLGNFLEHRAdggearllipadtFKDQTFFLAGIPRQALQRTMFPLGDLAKNEVKLLARRIGlqRLAHKRESTGICFVGKRD-------------------------------------
>UniRef50_B4U7S9(2-190:196) ExsB family protein n=1 Tax=Hydrogenobaculum sp. Y04AAS1 RepID=B4U7S9_HYDS0  E=6e-19 s/c=0.51 id=23% cov=82%
--KVVSLVSSGFDSISLLNYYINKNYEIYPIYVKSGFKWEEEE------LKHLkDIIDHISKSYKLIKPLKVSHAPNDFFEDFNERAFIND-EDVEIPFRNLDLLISALKYAYAVDANLIAIGIMG--LVAFKDNSYNFIKTINDLF--SMYGDYKVDTPFLGMSKKDVFDRY----FIKELFDKAFCCMNPTDGKECGVCSKCKE--------------------------
>UniRef50_Q12C76(147-365:466) Putative uncharacterized protein n=1 Tax=Polaromonas sp. JS666 RepID=Q12C76_POLSJ  E=7e-19 s/c=0.44 id=20% cov=84%
--------SNGLDSFALANQVQRDSSTTELILIN--------VQAA-----------HRLTNWKNLGRARDKDMQAVQVAVFFNEPHRTEPS---FRSRPFIYDMLAGYGASLAQPAKVVIPENGqgslggslvplGDEAPHRSCHPGFTSRLTRLVNALTNVTVRFEHPALFQTKGQVLAqLASQKSASEAWLAGHRSCsydarhsSQDKRSMHCGVCGNCLLRRVALKWTGIEDTTDYRA--------
>UniRef50_C6J374(180-337:410) Thiamine biosynthesis/tRNA modification protein ThiI n=2 Tax=Bacillales RepID=C6J374_9BACL  E=1e-18 s/c=0.61 id=24% cov=68%
--KAMLLLSGGIDSPVAGWSALRRGLEIECVHFHsYPFTSKKAEQKVIDLANVL-------AQYSGFIKLHLVPFTEIQTKLAQ-----TGQDNLIITMMRRAMLRIATKLAERNGALALVTGDSLGQVAS---------QTLSSMNAIGRVTNLPILRPLVMTDKVDIIAMAQQIGTYDL---------------------------------------------------
>UniRef50_D2MP56(177-333:472) Thiamine biosynthesis/tRNA modification protein ThiI n=1 Tax=Bulleidia extructa W1219 RepID=D2MP56_9FIRM  E=2e-17 s/c=0.59 id=19% cov=67%
--KVMMLLSGGIDSPVATYQLIKRGLKVEAVHFAAPPYTS---EAAKN-------KVLKLASMISDYQGGMKVHVVPFTELQLDIYRVAKDPYAITLMRR-MMFRIAEKLAINNRCLAIGTGESLGQVAS---------QTLESMVTINDVVHIPVLRPLVSMDKVEIIQLAREIG-------------------------------------------------------
>UniRef50_Q8A525(141-353:435) Putative GMP synthase [glutamine-hydrolyzing] 2 n=37 Tax=Bacteria RepID=GUAA2_BACTN  E=4e-17 s/c=0.42 id=21% cov=77%
-KKVLLALSGGVDSSVVAALLLKAiGENLVCVHVNHGLMRKGESEDVVEVfSNQLKANLVYVDVTDRF--------LDKLAGVEDPEQKRKII--------GGEFIRVFEEEARKLdGIDFLGQGTIYPDIVESGTKTAKMVKSHHNVGGLPEDLKFQLVEPLRQLFKDEVRACGL---ELGLPYEMVY--RQPFPGPGLGvRC-------------------------------
>UniRef50_B6YWN1(2-162:196) ThiI-related protein n=5 Tax=Euryarchaeota RepID=B6YWN1_THEON   E=4e-17 s/c=0.56 id=23% cov=70%
--KAVALLSSGIDSPVAIYLMLRKGMEITPVHFK--QSDKKESK-VLELCE-------ILSKYGKLNEPVIVDAYEEQAPVFSKLVEIGKAKWTCL-FCKYTMLRKACRVGHEIGAKAIVTGDSLGQVAS---------QTLDNLLIISQASDLPILRPLIGRDKEEIVKIAKEIGTFEISIE------------------------------------------------
>UniRef50_Q980G6(170-329:371) Probable tRNA sulfurtransferase n=4 Tax=Sulfolobus RepID=THII_SULSO   E=5e-17 s/c=0.56 id=17% cov=66%
--KTVVLFSGGIDSPVATWMMMKRGSVPIILNFNLGGDLHKEL-----VLKELN------MLKRWSGGHKLKIFIVKGTDVFIKLSQVERRSRVVMLKR--VMYKTAEKLCEKTNAKSITTGESLSQVSS---------QTMANLYVTEYGIKYPIFRPLIGFDKEEIVDIARKIG-------------------------------------------------------
>UniRef50_B3RIL6(8-211:369) Putative uncharacterized protein n=1 Tax=Trichoplax adhaerens RepID=B3RIL6_TRIAD  E=5e-17 s/c=0.44 id=20% cov=71%
-----VAMSGGVDSTIAAYLLRKQGHEVVGIFMKNWDiteetgicKTDEDMQDFIKSCNHLGIPHKEVNFVQDYWHHVFSPFVNGYKQGITPNPD-------ITCNRMIKFNKLRQYCSENLGVDNLATGHYAQLVTDSKPKLIQAVDeAKDQTYFLANVKKISlknIMFPIGNLLKSEVKNLALKIG-------------------------------------------------------
>UniRef50_A7ZEK1(2-182:340) tRNA-specific 2-thiouridylase mnmA n=4 Tax=Campylobacter RepID=MNMA_CAMC1  E=1e-16 s/c=0.49 id=25% cov=26%
--KIMVAMSGGVDSTMTAKFLQEAGHEVQGCYMMLHQKpgyHEENIRKVKKVGEYLGIKVHIL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B9JNY0(142-361:457) Putative uncharacterized protein n=1 Tax=Agrobacterium radiobacter K84 RepID=B9JNY0_AGRRK  E=1e-16 s/c=0.40 id=20% cov=83%
--KVVTPFSDGLDSRAVTAMMTA------------GGRSD------RLIRVRVGAK----TDDRPRTEHRKAPFLTIPFKVKSGDR---PFAESTVRSRGFKFTLLSGIAAYLLGTHDIVMPESGQGAlgpslvqtshgYEDYRNHPLFFGRMERLVAAIFNYQVSYRLPRLWKTKGQTLGEFAALPVNPNEWVKTRSCWQqnrnssvDGKRRQCGICAACMLRRLSFHAAGLEEP-------------
>UniRef50_D0XY41(143-349:458) Putative uncharacterized protein n=1 Tax=Caulobacter segnis ATCC 21756 RepID=D0XY41_9CAUL  E=1e-16 s/c=0.43 id=19% cov=82%
--KTIIPYSNGLDSLAVAALTSEA--------------RPSDLVRVRLGAAFADQKSH-------NKRRQAFASVPYEVRVAKGRRKESSARS-----RGFKFAVITGIAAVLAKADKIVVTESGqgalgpvltvsGQAYPDYRVHPAFTMRVERLFATLLGHSAHYDFPRLWSTKGETIAEAARATP--QPWAETRSCWQqsrqvgmGGKQRQCGVCAACMLRRMSLHAAGVVEPA------------
>UniRef50_C4QP81(27-267:312) tRNA(5-methylaminomethyl-2-thiouridylate)-methy lt ransferase,putative (Fragment) n=1 Tax=Schistosoma mansoni RepID=C4QP81_SCHMA  E=2e-16 s/c=0.37 id=17% cov=90%
--------SGGVDSAVSAYLLKKKGFQVKGVFMTNWDsldekidcSLDKDRQDAQFVCDYLGIPFFEKNFVKEYWNYVFLPLIKSYEQGATPNPDILCNRFVKFNLLTRAVLKSKNQCADddsqassNLAADAIATGHYCQNSFGNYlQYRKDNVEArllrsvdrvKDQTFWLSTISHKELpycMFPVGDLLKTQVKQIAQDIG-----LSRIYS-----RRESMGMCFIGKRRFSEFIDnYLEPKPGVYKDLE------
>UniRef50_A4RU81(256-425:714) Predicted protein n=3 Tax=Ostreococcus RepID=A4RU81_OSTLU   E=4e-16 s/c=0.51 id=22% cov=71%
-----VSLSGGVDSMVLAYILKHQGYDVVTLHIDYKNRPESTEEA--DFVDDWSLRH-----GMKFERCTVDQIRRGVTPREQYEIESRRIR--------YGFYKEAGA---KHGFPAVLLGHHHGDVQENiitNLMRGANLLSVNGMSDEGVVEGVRIWRPMLSHVKDDVLTFAHAYGiPYFLDSTPTWS--------------------------------------------
>UniRef50_C3MZC6(172-326:373) Probable tRNA sulfurtransferase n=7 Tax=Sulfolobus islandicus RepID=THII_SULIA  E=6e-16 s/c=0.56 id=17% cov=66%
--KTVVLFSGGIDSPVATWMMMKRGSIPVILNFNLGGS----------VHRKFVLEELSVLRKWSGGHKLKLFIVNGTDVLIKLSQIEKRNR---VVMLKRVMYKVAERLCDKANVKSITTGESLSQVSS---------QTMTNLYVTEYGIKYPIFRPLIGFDKEEIVELARKIG-------------------------------------------------------
>UniRef50_B0TD47(152-375:453) Putative uncharacterized protein n=1 Tax=Heliobacterium modesticaldum Ice1 RepID=B0TD47_HELMI  E=1e-15 s/c=0.38 id=17% cov=85%
----VSLFSGGMDSLIFAINSLEEKKTPLFISHAgdgYTKNYQKEI-----------INTLSNNYADISFSQLNLWMSFNKHIVSQSCKENTTRSRSFLYISLALFALSGLPKVDILDvpengliAINVPLDDLRVGSHSTRTTHPYYFKLWNEILGI-VNLGKSIRNPYWNKTKGEMARDCLNKELLLDLLPISMSCsaptkyrYRGSTHMHCGHCVPCIIRRAAIN--------------------
>UniRef50_Q052I5(154-355:621) Putative uncharacterized protein n=1 Tax=Leptospira borgpetersenii serovar Hardjo-bovis L550 RepID=Q052I5_LEPBL  E=2e-15 s/c=0.42 id=20% cov=80%
-KTSVVLFSGGADSLAGVLELLNQTDGNVILSSHQLSSSAKKTQNAlyTSLEKKFGNRIHHYKYECHLS--------------------GKRATDETQRSRSFLFSSIAFVLARTFHQKEFYLFENGVtslnlfrredlmNSRASRTTHPQTLFKLMEFFSLVAGFQFEIKHNYVFKTKREVFEvIGKNSPEL---ISSTVSCTKAsfskGIATHCGRCFQCIDRR------------------------
>UniRef50_D0Y5H1(169-381:638) Putative uncharacterized protein n=1 Tax=Dehalococcoides sp. GT RepID=D0Y5H1_9CHLR  E=3e-15 s/c=0.40 id=17% cov=81%
----VMLFSGGLDSLAGAVELLEDSKDVICL-VSHQSQP--------------GTVKTQNGLFKALKDAYSDRVRHYQFKCSLVSTVNRAVEET-QRTRAFLYTSIAYAIASSQRNPRFYVHENGVtslnfarrqdgiNARTSRTTHPRTLSLLQDFFSLVHGSKVQVATPFLFKTKSDIFRELSAHKR-ENLIPSAVSCSKTFLNRkqasHCGGCFQCIDRR------------------------
>UniRef50_C8WLL2(6-214:352) tRNA(5-methylaminomethyl-2-thiouridylate)-methyl transferase n=1 Tax=Eggerthella lenta DSM 2243 RepID=C8WLL2_EGGLE  E=3e-15 s/c=0.40 id=20% cov=84%
--------SGGVDSAVSAALLMRAGYEVVGVTCRFrdNAATERAAADAAAVCSQLGIRHEAPGCVGEFERCVVEPFVSSYAAGLTPSPCVGCNARCKMPA--------LVRVAGELGCDRIATGHYARIARLSDSGRFVVKRALDArkdqsymLSLLSQEQLARLVLPLGAMTKAEVRVIAADLGLVVAEKAESQdNCFIEGDYRP-------FLRARGVEDAPGD---------------
>UniRef50_A1RWZ9(176-333:484) Thiamine biosynthesis/tRNA modification protein ThiI n=1 Tax=Thermofilum pendens Hrk 5 RepID=A1RWZ9_THEPD  E=4e-15 s/c=0.53 id=19% cov=67%
--KVLALISGGYDSAVAAWYMLKRGAEVHYLYCNMAGDLTKSL--VLSVAKKL-------ADSWSYGYKPRLYVADFSPLLRELRAKVAPELFGVVLKRY--MYRVAEAIAGRIGAIGIVTGESLGQVSS---------QTLENLYVASQATSMPIYRPLIGFDKEEIISKSKEIG-------------------------------------------------------
>UniRef50_Q13XN6(146-358:458) Putative uncharacterized protein n=1 Tax=Burkholderia xenovorans LB400 RepID=Q13XN6_BURXL  E=5e-15 s/c=0.39 id=21% cov=82%
-----VAYSNGLDSRAVSAL---SGDEGEALCI-------------------------RVAGNRQPRKDGDSYFTHIPFNISGYRGNESSFRS-----RGFQFAAVTAIAAQLSNVTRIVVPESGQGALGPvllplygvyadYRNYPTFFRKMERFIKALQGYQVRFEQPRLWFTKGQTLSAFLRIpGKSGEHLKSTRSCWQTrrvvnvGSRKQCGLCAACLLRRLSLHAAGVseaPDTYVVSDLAA-----
>UniRef50_B9B2T1(151-373:468) Putative uncharacterized protein n=2 Tax=Burkholderia RepID=B9B2T1_9BURK  E=5e-15 s/c=0.37 id=23% cov=78%
-----VPFSHGLDS--------------------YGQvrLWQREHPDTEVVCVFADARTSGVDHGNGLKRRTSEHIQYVRVPV---SVKPMRRAEPSFRSRPFMFYLLAGLGAIESGANKVMIPENGQGSiggslivtgheAKHRSCYPGFTTKLSRFVEALTGKRVKFYHPALFETKGAVLRaLADAGENVRAVLGRHRSCscdarltSRDEQMFHCGVCGNCLLRR------------------------
>UniRef50_UPI0001AF1546(21-205:402) argininosuccinate synthase n=1 Tax=Streptomyces roseosporus NRRL 15998 RepID=UPI0001AF1546  E=8e-15 s/c=0.45 id=19% cov=80%
---VVTLFSGGLDSSYLLLRLRRMGmREVHAVSVDIGEDESSSYK--QQVAEELGATIHILDRREEFAERYVAPAIAAQAVYLGIHPVSSTLSRP-------LIAHSAVELARGLGAQAVLHTANRSQNTLRRLNGALRLLRYEGAFGSPYDLD-PVTR--------DDKLVELRAAGIDLLAGRIVS---GDSNLWC----------REFESGILDDP-------------
>UniRef50_Q0EYL6(179-338:392) Putative uncharacterized protein n=1 Tax=Mariprofundus ferrooxydans PV-1 RepID=Q0EYL6_9PROT  E=5e-14 s/c=0.50 id=24% cov=69%
--RGVVLFSGGIDSPVAAYSMMKRGMEVVLVHL-YNSTINRDFAKIRDLARQLSLYQGRLTLHMIdLEEFQRHAIAKVDAEYRMIIYKRQ-------------MIRSAAAIAADAGAQALVTGDSLGQVAS---------QTLANIHAIYDASDLPLLSPLIAWDKEEIIALAKRIGTYEISIEE-----------------------------------------------
>UniRef50_A9A452(16-172:265) ExsB family protein n=2 Tax=Thaumarchaeota RepID=A9A452_NITMS   E=1e-13 s/c=0.50 id=24% cov=26%
--KVMIALSGGVDSALVAYAAyQKLGDFAIAVTADYKTLSEEELQTAKQICSEIGITQFFL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A5UKF9(17-171:336) ATP-utilizing enzyme, PP-loop superfamily n=3 Tax=Methanobrevibacter smithii RepID=A5UKF9_METS3  E=1e-13 s/c=0.51 id=27% cov=28%
-RKVAIAFSGGADSTLLAYLASEVSDDPIAITIDNHIFPTGFIKHCKKTAKEFGIR-HQIIDLNF----------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B6VWC2(147-381:471) Putative uncharacterized protein n=2 Tax=Bacteroidales RepID=B6VWC2_9BACE  E=2e-13 s/c=0.33 id=16% cov=88%
----VALFSGGLDSLIGFI------DEASTLSVDKKILLVSHMELGKEHSDQKSILK-YCRENNIFSNKYEQVLLNAGLK--PHSWNIKTPTESTFRSRSLLFFAAGIYIVNKIspQCQLIVPengtisINIPLDSGRRSSCstrttHPTFIKRIQEAL-YAIGISNSIYNPYRLKSKADMVLECCqdtsKKAILKSLVDLSCSCakrghnvfwdksgieIRNAKIKHCGMCLPCLYRRVALDTIGLDN--------------
>UniRef50_Q3AD57(1-214:338) Putative uncharacterized protein n=1 Tax=Carboxydothermus hydrogenoformans Z-2901 RepID=Q3AD57_CARHZ  E=2e-13 s/c=0.37 id=18% cov=83%
MVKALALFSGGLDSTLAIKLILEQGVEVEAVNFTSPFCRclakGQGCASTAKLAADLGIKLHVQNCGEEYLRIVENP------------PHGYGSALNPCIDCRIFKFKKAKKLMEEIGAKFMITGEVLGQ--RPNSQRRDAINLIDREAGIkglvlrplsALHFPPTIAEQEGYVSRDKLLAISGRSRKTQMELAASF----GINDYPCPS-GGCLLTKKEF---------------------
>UniRef50_C4F7E5(4-218:409) Putative uncharacterized protein n=2 Tax=Collinsella RepID=C4F7E5_9ACTN  E=2e-13 s/c=0.36 id=20% cov=75%
-KRVLVAMSGGVDSSVTAYLLTQQGYDCLGATMLLHGDAApgacgsgSDADDAAAICARLGFPHEVIDMRETFERHVVEKFVRT--------YETGRTPNPCIDCNRHLKFDALLSYAREHDCDFIATGHygrigtlaEGGGGSVRRGEEQEFVARI--TARTGASNAVHTLSCALDPSKDQsyvlysltQERLARTLLPLGGLFKE-----------------------------------------------
>UniRef50_Q7URE0(28-192:316) Putative uncharacterized protein n=1 Tax=Rhodopirellula baltica RepID=Q7URE0_RHOBA  E=2e-13 s/c=0.47 id=33% cov=26%
MGGLVVAFSGGVDSSVVAAAAHRTGRDVVAVTAQSPAVARWQLDWARRVAEQVGITHQFV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C9LNF1(36-194:285) PP-loop family protein n=1 Tax=Dialister invisus DSM 15470 RepID=C9LNF1_9FIRM  E=3e-13 s/c=0.49 id=30% cov=26%
MGTVAVAFSGGVDSTFLLHEAHAvLGKKAVAVTMKLNSFPFREWKDAKEFCKREHIRQMIV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q6L1T4(171-325:469) Hypothetical thiamine biosynthesis protein thiI n=1 Tax=Picrophilus torridus RepID=Q6L1T4_PICTO  E=9e-13 s/c=0.49 id=24% cov=64%
---ALSLFSGGNDSPLATYMVMKRGspCDLLFCSFAHPEDTYNMLLSARRLFDKY------------------SYGYDPLIYIIDGTELASRIMERNQKYGNLIFKKLLYLYADNLcslkNYNAMVTGESIGQVSS---------QTLENLRSLSHGIDHPILRPLIGFDKDEIVSKSRELG-------------------------------------------------------
>UniRef50_C1EG18(3-216:346) Predicted protein (Fragment) n=2 Tax=Micromonas RepID=C1EG18_9CHLO   E=2e-12 s/c=0.35 id=20% cov=76%
--RVAVGLSGGVDSAVTAWLLKSAGFDVTGVLMRNWDEAeetggecsfEKDQRDARAAARAVGIPLTEVDFVKEYWHSVFEPFLRDFD------GGGATPNPDLACNRHIKFGALLDHCLRSLGADLLATGHYARIVRIDETNPPRLLRGIdpdkDQSYFLASVRGESLERacfPLGGLTKREVRELA--AGPANLPAAVT----------------------------------------------
>UniRef50_Q8YA50(111-312:400) Lmo0312 protein n=6 Tax=Bacilli RepID=Q8YA50_LISMO   E=2e-12 s/c=0.37 id=21% cov=82%
-KECITLFSGGLDSFAGSY-----YNFLNNISSDYvGYVNKAEERTYQK----------------RLQSFYRKIFSAGGSEVDIRNKYQKPKIFYFQSTRSLLYLSLAISKAISNSVKEIRMYENGIlslnpefGRYTTKTTHPKTIFLYNKLLDT-LGYDIRIVNKFEYETKGEIVE--NMNLEFKSQIKNTFTCGKSRVGKeynhtgQCGACIPCILRKISLAAY------------------
>UniRef50_C1N3G9(279-455:758) Predicted protein n=1 Tax=Micromonas pusilla CCMP1545 RepID=C1N3G9_9CHLO  E=3e-12 s/c=0.42 id=22% cov=70%
-------LSGGVDSMALAVILKRLsrdasygGFDVVAMHIDYDNRPESgvEADFVRGWCDRMGIE----------------CVVRKIAEVTRGVTPREQYEAESRAIRYGFYKDVAKTHAF----PAVFVGHHEGDVQENiiaNLMRGANLLAVNGMEETGVVEGVAIWRPMLPHSKAVVLDFAHKYGvPYFLDSTPTWS--------------------------------------------
>UniRef50_Q8ZT92(212-381:505) GMP synthase [glutamine-hydrolyzing] n=7 Tax=Archaea RepID=GUAA_PYRAE  E=4e-12 s/c=0.43 id=30% cov=23%
--DVIVGVSGGVDSTVTAVLLYKAvGQRVKAVFIDHGLFREGEPEEAASLLKSIGI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A8UGA3(7-208:220) Putative uncharacterized protein n=1 Tax=Flavobacteriales bacterium ALC-1 RepID=A8UGA3_9FLAO  E=6e-12 s/c=0.36 id=21% cov=82%
-----VLWTGGWDSTFRVIQLYRLGATIQTIYIIDQKRksSNKEIEVINSLAEK--TPLH-------FNQSNGHILPIKYIKRENIPYNLFLKVIHKILRRQVGLgkqYYWLASFAQKHKNLDVSFHKEDLDKFFSEEQLIEIKDDNFGSNWKINPKKVGFLRrqlfknmtfPLITVTKPEMKFIAEENNFIEL-MELTWFCHKST-DKPCGKCAPCK---------------------------
>UniRef50_UPI000194D842(7-121:397) PREDICTED: argininosuccinate synthetase 1 n=5 Tax=Amniota RepID=UPI000194D842  E=4e-11 s/c=0.61 id=32% cov=26%
---VVLAYSGGLDTSCILVWLKEQGYDVVAYLANIGQK--EDFEAARRKALALGAKKVYIEDIS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B1I6R5(18-173:265) ExsB family protein n=1 Tax=Candidatus Desulforudis audaxviator MP104C RepID=B1I6R5_DESAP  E=7e-11 s/c=0.45 id=41% cov=23%
---VVVALSGGVDSATVLCLAREvLGERVAAATAVAGIHARADLQRARALAALLGVR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A5UJL7(143-342:343) Predicted ATPase n=3 Tax=Methanobrevibacter smithii RepID=A5UJL7_METS3  E=3e-10 s/c=0.34 id=16% cov=81%
---AVVALSGGVDSSFSLILAKYLGFNPTAVTIDPGtiILPNQYKRNIKKLTDQLNAGHEYIKA--DYSEIIRESLNGRFHPCGRCSKHTEELINQYAINNNIPIVIFGDMLSTGTQCitpqeKGLYRLNLPASLAVGKQENKSLTQQfdLQSFSGFGCPLLYEVHRKYPYLKKYSIQRILREtrssALEVGEALDLIWSFYN-----------------------------------------
>UniRef50_Q58873(52-169:303) CTU1/ATPBD3 family protein MJ1478 n=14 Tax=Euryarchaeota RepID=Y1478_METJA  E=5e-10 s/c=0.57 id=23% cov=26%
-EKILVAVSGGKDGHAAAWVLKKLGYNIELFHINLGIEGFSEesLKAVKELAEKLEVPLHVV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q8TUR3(11-168:264) Predicted ATPase of the PP-loop superfamily implicated in cell cycle control n=1 Tax=Methanopyrus kandleri RepID=Q8TUR3_METKA  E=6e-10 s/c=0.42 id=18% cov=68%
-KKICVLISGGMDSAVATKILQLSNTDVRGLHITHRWMWFTPEIEIKRISKMLGIKIDVVDITDELRRRLRGAKGKSVCKI-----------------CKKIMLEIAVSKASVVATGECGMDTIAGavlDVSRRTGIEPEFVQLPKRYFN---GDDRIIVRPLIRIHESDVKRLARLLG-------------------------------------------------------
>UniRef50_A0ZA07(222-390:496) Asparagine synthase B n=2 Tax=Cyanobacteria RepID=A0ZA07_NODSP   E=2e-09 s/c=0.38 id=30% cov=23%
-----VFLSGGLDSSIIAALMRQHIPNLH--SFSVGLPNSPDLKAARLVAEHLGTIHHE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C0Z6S0(5-188:419) Argininosuccinate synthase n=32 Tax=Bacteria RepID=ASSY_BREBN   E=3e-09 s/c=0.35 id=29% cov=26%
--KIVLAYSGGLDTSVAIKWLQDTYnYDVIAVALDVGE--GKDLDFVQKKALQVGALKSIVVD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A9V8Y1(9-209:495) Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9V8Y1_MONBE   E=3e-09 s/c=0.32 id=27% cov=26%
--------------------------------------------------------------------------------------------------------------------------------------------------------------PLGHLTKDRVKALAAAAGFSDV----------AGQRESMGLCFVGKRRFGALvQQYLPPRPGVFVHLES-----
>UniRef50_Q2S0G2(3-119:413) Argininosuccinate synthase n=4 Tax=Bacteria RepID=Q2S0G2_SALRD   E=4e-09 s/c=0.55 id=32% cov=26%
----VLAFSGGLDTSFCVPYLQAtHDAPVHTVTVDTGGLTDDDRTAIEARARHLGADRHHLID-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C5DPR0(5-116:419) Argininosuccinate synthase n=1 Tax=Zygosaccharomyces rouxii RepID=C5DPR0_ZYGRO  E=4e-09 s/c=0.57 id=36% cov=26%
--KVCLAYSGGLDTSVILAWLLEQGYEVVAFLANVGQ--EEDFDAAREKALKIGASKFVCVD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C2KYF0(23-197:342) Possible tRNA(Ile)-lysidine synthase n=1 Tax=Oribacterium sinus F0268 RepID=C2KYF0_9FIRM  E=5e-09 s/c=0.36 id=14% cov=72%
----LLALSGGADSMYLLYFLKElqnhLSFSLRAMHVQHGIRGDEAVEDAtfsRQQAELYQVPFLE--YTCSVPDYAEENKLGIEEAARTLRYKALKEEALRWQAESGRKTKIALAHHMDDQAETILFHLIRGAGFSGISGM--------KAEDLLSEAETTLLRPLLSLRKEEILK---RLEELGIPY-------------------------------------------------
>UniRef50_Q7MFV1(18-203:404) Argininosuccinate synthase n=4 Tax=Vibrio RepID=Q7MFV1_VIBVY   E=8e-09 s/c=0.34 id=18% cov=52%
-KHVLTLFSGGLDSSYLLEILKNSRAKVTAVAIDLG--DDIEESKLKLITDHYGFDLKILDAKQEFVEHSLFSAIQAQALYLGDYPVSSSLSRP-------IIVKKAVELAQILGCDAIIHTANQSQNS------------------------------------------------------------------------------------------------------
>UniRef50_B5JCX8(958-1077:1398) ExsB family n=1 Tax=Verrucomicrobiae bacterium DG1235 RepID=B5JCX8_9BACT  E=9e-09 s/c=0.52 id=31% cov=31%
----MVFFSGGKDSAYALCQLVDMGLNVYAFTLDNGYLSDQAMANISRVTKSLGVE-HEFATTPAMNEIFRDSLTR-----------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_UPI0001BC31C1(21-172:457) cell cycle protein MesJ n=1 Tax=Butyrivibrio crossotus DSM 2876 RepID=UPI0001BC31C1  E=1e-08 s/c=0.41 id=24% cov=23%
---VIVGLSGGADSVALFHVLRELrsryGFSIIAVHVHHGIRgeeADRDLDFCRNLCRRYGVE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A7I0Q0(18-168:331) tRNA(Ile)-lysidine synthase n=1 Tax=Campylobacter hominis ATCC BAA-381 RepID=A7I0Q0_CAMHC  E=1e-08 s/c=0.41 id=29% cov=27%
FKRAILAFSHGSDSTALFHTLLDLNLKFDVAFVNYKTRENSDLEmvCARELCEKNNLKFHCLI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C4QEH8(214-293:739) GMP synthetase (Glutamine-hydrolysing) (Phosphoribosylformylglycinamidine syntethase) (Family c26 unassigned peptidase (C26 family)) n=1 Tax=Schistosoma mansoni RepID=C4QEH8_SCHMA  E=3e-08 s/c=0.77 id=27% cov=26%
--KILILLSGGVDSTVCAALLSKTLDpsQIIAVHIDNGFLRKNESLRVIESLKSLGIKVHLI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A4CKW5(22-173:439) Putative cell-cycle protein n=1 Tax=Robiginitalea biformata HTCC2501 RepID=A4CKW5_9FLAO  E=3e-08 s/c=0.40 id=23% cov=24%
----LLACSGGLDSMVLAHLCKDAGLEFELAHCNFnlrGEASESDQEFVRETADKLRIKTHI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C5A2Y4(199-261:528) Asparagine synthetase related protein n=1 Tax=Thermococcus gammatolerans EJ3 RepID=C5A2Y4_THEGJ  E=4e-08 s/c=0.97 id=40% cov=25%
-RSVVVPLSGGYDSRFIVTSLKQRGVDVICYT--YGRRDSPEVSVAKEVSKKLGCEWHFV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C4Z434(22-180:486) Cell cycle protein MesJ n=1 Tax=Eubacterium eligens ATCC 27750 RepID=C4Z434_EUBE2  E=5e-08 s/c=0.38 id=30% cov=24%
-ERVVVGLSGGADSVCLLMVLKgyierrRLQTELCAVHVNHGirQEAGDDEEFARALCERMGVE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B1WQP9(226-382:501) Asparagine synthetase n=5 Tax=Bacteria RepID=B1WQP9_CYAA5   E=7e-08 s/c=0.38 id=33% cov=22%
-------LSGGLDSSIIAAIAKKHKSELH--TFSVGVEGSKDINAARLVSDYLGTIHHE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_UPI0000DB7B98(248-395:528) PREDICTED: similar to asparagine synthetase n=1 Tax=Apis mellifera RepID=UPI0000DB7B98  E=7e-08 s/c=0.40 id=23% cov=25%
-----CLLSGGLDSSLIAALLVKHAKDANLsykiKSFAIGMGDSPDIIAARQVAEYIGTEHHEII--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1PEM2(272-398:595) Asparagine synthase n=1 Tax=Prevotella copri DSM 18205 RepID=D1PEM2_9BACT  E=2e-07 s/c=0.46 id=27% cov=24%
-----VLLSGGLDSSVISAVAekysstrVENGGETKAYwprlhSFAVGLKGAPDLAKARLVAEHIGTVHHEI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C5BIC0(163-215:432) Asparagine synthase family protein n=1 Tax=Teredinibacter turnerae T7901 RepID=C5BIC0_TERTT  E=2e-07 s/c=1.10 id=32% cov=22%
-----VALSGGLDSSTMAHYAKRFCANPIAVTLDLG--GSEDAEKAQKIAAQLAIR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A5ERG8(32-189:358) tRNA(Ile)-lysidine synthase n=16 Tax=Rhizobiales RepID=TILS_BRASB   E=3e-07 s/c=0.37 id=31% cov=21%
-------VSGGPDSMALMWLAARWratragGPRLLAVTVDHGLRPESRREAlmVKQLARQLG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A8EQV6(249-425:595) Asparagine synthetase (Glutamine-hydrolyzing) n=2 Tax=Campylobacterales RepID=A8EQV6_ARCB4  E=3e-07 s/c=0.33 id=22% cov=24%
------LLSGGIDSSLISALYTKiSGNKINTFSIGYdEYKNYCELDYAQITAKHINSNHHPV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q2NH13(237-449:474) Putative asparagine synthetase n=1 Tax=Methanosphaera stadtmanae DSM 3091 RepID=Q2NH13_METST  E=4e-07 s/c=0.27 id=20% cov=22%
---VALLFSGGVDSTLIALILKKLGIKTTLYSV--GVETSQDLKYAKKIAHDIDI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C7BSC5(273-401:643) Asparagine synthase, glutamine-hydrolyzing n=1 Tax=Photorhabdus asymbiotica subsp. asymbiotica ATCC 43949 RepID=C7BSC5_PHOAA  E=7e-07 s/c=0.44 id=25% cov=21%
-------LSGGVDSSTIVSLMQSHSKRPIqTFTIGFNEENYNEAEYAKAVAEHLG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A0M509(224-341:536) Asparagine synthetase [glutamine-hydrolyzing] n=2 Tax=cellular organisms RepID=A0M509_GRAFK  E=7e-07 s/c=0.48 id=28% cov=23%
-----VLLSGGLDSSLtssIAARLMEgSGQKLH--SFSIGLDAEaPDLIAARKVAEFLGTEHHEI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C8QZJ8(225-376:543) Asparagine synthase (Glutamine-hydrolyzing) n=1 Tax=Desulfurivibrio alkaliphilus AHT2 RepID=C8QZJ8_9DELT  E=9e-07 s/c=0.37 id=22% cov=24%
-------CSGGLDSSLIAAIAAEEIPNLHTFAVgmrDENGKESDDLTAARLVAEHIDSTHHELI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B5IFS1(245-312:580) Phosphoadenosine phosphosulfate reductase n=2 Tax=Aciduliprofundum boonei T469 RepID=B5IFS1_9EURY  E=1e-06 s/c=0.82 id=27% cov=24%
-----VSFSGGKDSLAVLLLALKSGMDFHTFFLNTGIELPETVEYVNEIEKKYGIKMDRI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C0W8C3(193-256:549) Putative uncharacterized protein n=1 Tax=Actinomyces urogenitalis DSM 15434 RepID=C0W8C3_9ACTO  E=1e-06 s/c=0.87 id=32% cov=26%
--RLVIPLSGGLDSrLLVAWLALHDQIRPgRALAFTYGVPGAREVEVSRQVAQQVGLEWHTV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q74M42(179-228:352) NEQ525 n=1 Tax=Nanoarchaeum equitans RepID=Q74M42_NANEQ   E=2e-06 s/c=1.10 id=28% cov=22%
----VIPFSGGKDSTTVAILAKKAKVDFDLVFVDTGLEFKQTLEYIDYISKKI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B4TWE1(13-75:447) Argininosuccinate synthase n=178 Tax=Bacteria RepID=ASSY_SALSV   E=2e-06 s/c=0.87 id=27% cov=24%
-------FSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEDDYDAIPRRAMEYGAENARLID-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C0DBI7(23-83:499) Putative uncharacterized protein n=1 Tax=Clostridium asparagiforme DSM 15981 RepID=C0DBI7_9CLOT  E=2e-06 s/c=0.90 id=28% cov=22%
--RVVAAVSGGADSVCLLALLCglrgELGIQVRAVHVHHGLRgdeADRDAEFVRQLCE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C7PAG8(264-318:633) Asparagine synthase (Glutamine-hydrolyzing) n=1 Tax=Chitinophaga pinensis DSM 2588 RepID=C7PAG8_CHIPD  E=3e-06 s/c=0.99 id=28% cov=22%
-----VFLSGGYDSSSVAAILQAsSGSRLKTFTIGYKEAAFDESKEARRIAQHLG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_P22106(232-358:554) Asparagine synthetase B [glutamine-hydrolyzing] n=319 Tax=cellular organisms RepID=ASNB_ECOLI  E=5e-06 s/c=0.42 id=25% cov=24%
-----VLLSGGLDSSIIsaitkkyAARRVEDQERSEAWwpqlhSFAVGLPGSPDLKAAQEVANHLGTVHHEI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q83XP1(199-258:458) Putative beta-lactam synthetase n=1 Tax=Streptomyces cattleya RepID=Q83XP1_STRCT  E=6e-06 s/c=0.89 id=27% cov=24%
-----VMLSGGVDSSSVAALAAREVTSLSTYTV--GTPFGDEFAQAAWFAERLGSKHHELV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q8TXP0(242-330:524) Predicted RNA modification enzyme consisting of a 3-phosphoadenosine 5-phosphosulfate sulfotransferase fused to RNA-binding PUA domain n=1 Tax=Methanopyrus kandleri RepID=Q8TXP0_METKA  E=8e-06 s/c=0.59 id=31% cov=21%
-------FSGGKDSLVTLVVAAEAGVE-RALFVDTGMELPETVEAADRAAEAVGI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A5D5U6(22-183:473) Predicted ATPase n=1 Tax=Pelotomaculum thermopropionicum SI RepID=A5D5U6_PELTS  E=1e-05 s/c=0.33 id=23% cov=46%
--KVLVAVSGGPDSVALlhaLYLLKEELEiSLHVAHLNHmfrGAESEAEALFVADMARRYGLP--------------ATVEARDVPAYQKQSGLSAQAAAREVRFR---FFSEAAGKA---GASRVALAHHADD--------------------------------------------------------------------------------------------------------
>UniRef50_C8WM75(171-307:508) Putative uncharacterized protein n=1 Tax=Eggerthella lenta DSM 2243 RepID=C8WM75_EGGLE  E=1e-05 s/c=0.38 id=19% cov=58%
-RTAVIPITSGLDSRTIAACLKAADYE-RVLTFSIGARDSEDVMIGKRVASNLGFPWEHVEITGEMWRER----------FASDRYREALRYSILGGRINHILMAFALDILKGRGAlpdDAVFLPGHAGSImGGELKCSPVFKRAISKA--------------------------------------------------------------------------------------
>UniRef50_A4WQ07(21-140:412) tRNA(Ile)-lysidine synthetase n=2 Tax=Rhodobacteraceae RepID=A4WQ07_RHOS5  E=2e-05 s/c=0.43 id=31% cov=21%
-------VSGGGDSMALLHLAAEAGIAARAVTVDHGLRPEAAAEALEvgRVCTRLGV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A1VRB1(32-90:328) tRNA(Ile)-lysidine synthase n=10 Tax=Comamonadaceae RepID=TILS_POLNA  E=3e-05 s/c=0.87 id=30% cov=24%
-----VAYSGGADSTALLLAAAERWPgQVQAFHIHHGLQAAADdfVRVCESVCAKAGLPLHIV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q982D6(246-357:520) Mlr9125 protein n=1 Tax=Mesorhizobium loti RepID=Q982D6_RHILO   E=3e-05 s/c=0.46 id=30% cov=24%
-----VMLSSGVDSAVIAATLRriRRDSEIHTFTVGYGY-DDPEIIGASATASVLGTQHHEII--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_UPI0001B551B5(259-447:602) asparagine synthase (glutamine-hydrolyzing) n=1 Tax=Streptomyces sp. C RepID=UPI0001B551B5  E=4e-05 s/c=0.27 id=32% cov=25%
-----VITSGGLDSSYTTALAAHLVSDVASFNIAYrGDWPADERHWAAEVARHCGTEHHQVL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C9RYA6(259-359:635) Asparagine synthase (Glutamine-hydrolyzing) n=26 Tax=Bacilli RepID=C9RYA6_GEOSY  E=4e-05 s/c=0.50 id=35% cov=21%
-------LSGGIDSSFIVAIAKQFHPNLKTFSVGFEREGFSEIDVAKETAEKLGV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A8ZX58(229-369:537) Asparagine synthase (Glutamine-hydrolyzing) n=3 Tax=Bacteria RepID=A8ZX58_DESOH  E=4e-05 s/c=0.36 id=29% cov=23%
--------SGGLDSSLVAAIAADEIPRLH--TFVVGMKDafgdvSDDVKAARIAAAHIGSTHHELI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A8ERB6(12-100:326) tRNA(Ile)-lysidine synthase n=3 Tax=Epsilonproteobacteria RepID=A8ERB6_ARCB4  E=5e-05 s/c=0.57 id=28% cov=23%
--KNLLAFSAGVDSSALFFLLLKQNIPFDIAIVNYNVRvqSKDEVNYAKELASKYN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D2JNW7(260-318:647) Asparagine synthase n=1 Tax=Nostoc sp. 'Peltigera membranacea cyanobiont' RepID=D2JNW7_9NOSO  E=5e-05 s/c=0.85 id=30% cov=23%
-------LSGGLDSSTVLGMAARHtSHPIQAFTIAFDRPLDDEQAFARETVEHVGANLHIL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q313G0(241-297:595) Asparagine synthase (Glutamine-hydrolyzing)-like n=1 Tax=Desulfovibrio desulfuricans subsp. desulfuricans str. G20 RepID=Q313G0_DESDG  E=6e-05 s/c=0.88 id=31% cov=23%
---AAVMLSGGIDSRLQLALAVRHGAVPRAVIVSQPEHSAgAERRFARRVARQFG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A3SPZ7(181-244:532) Putative uncharacterized protein n=1 Tax=Roseovarius nubinhibens ISM RepID=A3SPZ7_9RHOB  E=6e-05 s/c=0.78 id=35% cov=23%
----VLPLSGGRDSRHILLELLHQGRAPEAcVTFHHnGYAFNSEAQAARALCQRAGI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B6B0H7(15-173:389) tRNA(Ile)-lysidine synthetase n=1 Tax=Rhodobacterales bacterium HTCC2083 RepID=B6B0H7_9RHOB  E=7e-05 s/c=0.31 id=36% cov=23%
-------LSGGSDSTALLVLAVDAFgaENLQAITIDHGLraAAQAEARQAAKLCASLGV-PHTI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B9ZCT0(201-291:535) Asparagine synthase n=1 Tax=Natrialba magadii ATCC 43099 RepID=B9ZCT0_NATMA  E=0.0002 s/c=0.53 id=29% cov=21%
----ILFLSGGYDSRLLAYMLHKHeADNVYAVT---GDQQNDEFNHAGRISKELG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B8HUI9(267-326:632) Asparagine synthase (Glutamine-hydrolyzing) n=1 Tax=Cyanothece sp. PCC 7425 RepID=B8HUI9_CYAP4  E=0.0002 s/c=0.80 id=27% cov=24%
-----VFLSGGIDSSTNAALFSEHSStPVKTFSIGYAgeyQSYQNELHYAQRMAQEVKAEHHE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q89GP7(269-430:625) AsnB protein n=1 Tax=Bradyrhizobium japonicum RepID=Q89GP7_BRAJA   E=0.0003 s/c=0.29 id=20% cov=34%
-------LSGGIDSSAVVATMVKHSTEpVRTFSVGFRETGYSELDHARVIAGQFGTIHnDLIVEPSAFMDHWSTAALRRGAPVSEAS--------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q8U4N3(1-235:240) 7-cyano-7-deazaguanine synthase n=3 Tax=Pyrococcus RepID=QUEC_PYRFU   E=1e-42 s/c=0.74 id=32% cov=95%
MKrRAVVLFSGGLDSTACLYWAKKQYDEVIMLTVNYGSNEERvTNKVAEYFSKELDVRLKIVklDFLKEFSEIRGSSLVGGEVPrvtaeeLEDIEKASETARSVWIPARNLVLISVAASLLDALGGGDIIVGFNAEEATTFPDNSREFVEKLNEALRFATLNPVKVVAPLIDLDKRGI---AKLLKELNAKYEYSNSCYNPkgftedGRPIHCGECESCVRRHKGLIEGIGEDKTVYA---------
>UniRef50_Q8TWG9(1-227:229) 7-cyano-7-deazaguanine synthase n=1 Tax=Methanopyrus kandleri RepID=QUEC_METKA  E=4e-40 s/c=0.74 id=27% cov=94%
MATTVVLCSGGLDSSVIAKWAVEElGGRVICLFVDYGQRNAPfERRAAERIAEAVGAEFETVGTFWLRRLCPDNPMFAGRLP---REAGTEDLSANWLPARNWNLLGVAAALCDHLYLEgeddefHIVWGINAEEAERFPDNTKEFADAVAEALKRGLPSRPRLHSPLAELYKPGIVRLG---SELGAPMELSVSCYNPIWEDdtpvHCGECEACYHRKRAFERAGIEDPTEY----------
>UniRef50_D2L9Z8(3-194:201) ExsB family protein n=1 Tax=Desulfovibrio sp. FW1012B RepID=D2L9Z8_9DELT  E=8e-26 s/c=0.62 id=27% cov=80%
-KNSAILLSGGMDSTSLAFWKKPNF----AFTIDYGQKAAmAEIRAARQVAKEIGISHDTIAI---------DCSSLGSGDMAMAAPLPNAPSTDWWPFRNQLLITLAAMKAICRNINLLYIGLVKSDSS-YKDGCSDFVDKISRTLSF-QEGNIEVMAPAIDMTAAELVNMSKIPRTL---LAWSHSCH--VSDFACGRCRGCN---------------------------
>UniRef50_Q3JDB4(139-354:425) Putative uncharacterized protein n=1 Tax=Nitrosococcus oceani ATCC 19707 RepID=Q3JDB4_NITOC  E=3e-24 s/c=0.52 id=18% cov=84%
----VTLLSGGLDSFVGAIDLVADGKAPFAVS----QVAAGDKQSQADFAAKIG---------------GGLNHLQLNHNVKCPGENERSQR-----ARSFIFLAYGVLAAsaqkhyhdgERVDLYICENGLISINppltparlgSLSTRTTHPVFLGLFQRLLDVA-ELRIAVRNPYQFRTKGEMLLECKDQAFLRKHAAETTSCgrYARNGWQHCGRCFPCLIRRAAFHAWGKDDRTKY----------
>UniRef50_C7RWC1(2-196:201) ExsB family protein n=4 Tax=Proteobacteria RepID=C7RWC1_9PROT   E=5e-24 s/c=0.58 id=24% cov=79%
---AALLLSGGMDSISIAWWKHPD----IAITIDYGQlPAAAEITASQAICRRLRIPHHVLQ---------VDCHSLGSGDMAGLEPNALAPATDWWPYRNQLLITLAAMKAVTLEVRQLWLGTVASDAS-HRDGTPNFLSAMSALLAV-QEGGLTVSAPAIGMSTVDLVRQS---GVPLEILAWAHSCHKA--DVACGACRGCN---------------------------
>UniRef50_Q1LLD1(137-352:419) Putative uncharacterized protein n=1 Tax=Cupriavidus metallidurans CH34 RepID=Q1LLD1_RALME  E=1e-22 s/c=0.50 id=18% cov=85%
-RDCVALLSGGLDSLIGGIDAVAKMRRPIFVS----QLAYEDSERQRQYAAALgGAAWHQQW---------------------SHRIDPAAPREPSTRARSMGFYAlavLATSLLTTTGPAEILVPENGFISVNPPllpgrmaslstrTTHPLFMKQLQGLLK-AVGIPANLSMPYRFKTKGEMMMECLDQKLLAHFASDSTSCgrYRTYNRTHCGRCVPCMVRRAAFLRWGQADDTRYK---------
>UniRef50_Q72HP1(176-331:406) Probable tRNA sulfurtransferase n=3 Tax=Thermus RepID=THII_THET2   E=2e-22 s/c=0.69 id=24% cov=67%
--RVVALLSGGIDSPVAAYRLMRRGAEVVLVHFHpFPLLSGASREKAKALAERLARFQHRLRL-----------HLVPFSEVQRHIIVEAPTAYRVVLYRRY-MLRIAEAIAREEGALALCTGDSLGQVAS---------QTLENLHAVNQAATLPVFRPLIGWDKEEIVAEAQRIG-------------------------------------------------------
>UniRef50_O27720(179-338:389) Probable tRNA sulfurtransferase n=5 Tax=Methanobacteriaceae RepID=THII_METTH  E=2e-21 s/c=0.66 id=21% cov=68%
--KVVALLSGGIDSPVATYLMMKRGCQVVAVHMDNAPFTGEEAeEKVEKIAAKL----------AEYSAGVEFKLRTFSYGRYLESCRRGAPEKMTCVLCKFGMYHLAEMVAEEEGALAIVDGSSLGQVAS---------QTLPNILATRMGVNIPILSPLIGMDKVEIENLAKRIG-------------------------------------------------------
>UniRef50_A7I9U0(1-161:213) Thiamine biosynthesis protein n=2 Tax=Genera incertae sedis RepID=A7I9U0_METB6  E=2e-21 s/c=0.65 id=19% cov=68%
MAKLVSLISGGIDSPVAAYLMLHQGVEIIAVHMDNRPFTDE-----KNLHKAMNLIRHLQHLTQRPIKTYVVPHGPNHIAFA-----RNCERHLHCLFCRRMMYRIAERIAEKEGAVGILTGESLGQVAS---------QTLQNLMVENLVIRIPVVRPLIGMDKVEIIDIARRIG-------------------------------------------------------
>UniRef50_A6D100(47-288:372) Putative uncharacterized protein n=1 Tax=Vibrio shilonii AK1 RepID=A6D100_9VIBR  E=2e-20 s/c=0.42 id=21% cov=75%
--KAVSLLSGGLDSFIGAIDLLNSDIDTLFVGHyakDGTQHYQNQVEQA--------LKGHY---PDYFKGYVKGCLIFDKSVFKGGNQEIDSENSQ--RSRSFMFLSMAAYLASSMGelcklivpengfiALNVPLDPLRIGANSTKTVHPNFMSKMGEIFDF-LGLNIGLINPYRHMTKGEMMANCKNKSLLTKHAHETLSC-------------------------------------------
>UniRef50_Q0AM89(149-356:439) Putative uncharacterized protein n=1 Tax=Maricaulis maris MCS10 RepID=Q0AM89_MARMM  E=1e-19 s/c=0.48 id=16% cov=90%
----VCLFSGGMDSLIGAIDRIADGHRPLLVS----RSTRGDGGYQTYLHGMLPEVPSLRINDDIRGELQGEPSTRTRSIVFLALAACAASAISRLHNDSIVPLIIPENGFISLNPP---LTVRRIGALSTRTVHPHFISSLQAIFDE-VGIPAAIENPYFFKTKGEALRECRDQPLVTKLISKTTSCGKWKRyWQQCGRCVPCLIRRSAFHAAGIADET------------
>UniRef50_UPI000197B781(15-195:361) hypothetical protein BACCOPRO_02286 n=1 Tax=Bacteroides coprophilus DSM 18228 RepID=UPI000197B781  E=8e-19 s/c=0.53 id=27% cov=24%
--KVLLGMSGGTDSSVAAMLLQDAGYEVTGITFRFYEKDFQTeyLEDARHLCEQLGIR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B7PXE7(5-222:384) tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase, putative n=1 Tax=Ixodes scapularis RepID=B7PXE7_IXOSC  E=1e-18 s/c=0.44 id=23% cov=73%
FRKVVCGMSGGVDSSVAAFLLRKSGYDVTGVFMRNWDPHDADSHcdldadetDAKWVCDTLGIPFMTVDFVKPYWHNVFSPMLQ--------EYQDGLTPNPDIMCNRVIKFGAFHRHAvKRFGADAVATGHYAR-IRNLPDGSVELLQGVDpvkdqsfFLSQVGQAALQRTLFPLGEATKGQVKALARSLG-------------------------------------------------------
>UniRef50_B3JKC8(6-203:353) Putative uncharacterized protein n=2 Tax=Bacteroides RepID=B3JKC8_9BACE  E=3e-18 s/c=0.48 id=30% cov=23%
--KVLLGMSGGTDSSVAALLLQDAGYEVTGVTFRFYEKDNNTeyLDDARELCERLHI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6KZ28(9-185:351) tRNA-specific 2-thiouridylase mnmA 2 n=10 Tax=Bacteroides RepID=MNMA2_BACV8  E=4e-18 s/c=0.53 id=24% cov=23%
--KVLLGMSGGTDSSVAALLLQDAGYEVTGITFRFYEKENDTeyLEDARALCERLNI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q9V1S6(2-161:198) ThiI thiamin biosynthesis protein thiI n=3 Tax=Pyrococcus RepID=Q9V1S6_PYRAB  E=5e-18 s/c=0.58 id=21% cov=69%
--KVVALLSSGIDSPVAIHLVASKGAEVYPLHFK--QDDVKE-NKVRRIVKRLQEIH-----GDKVKDPRIVDAFEVQGPVFEKLREIRKEKWTCI-FCKYTMYIVATSYAREIKAKAIVTGDSLGQVAS---------QTLDNLMVMSTATELPILRPLIALDKEEIVRIAKEIGTFD----------------------------------------------------
>UniRef50_Q47R41(203-358:422) Thiamine biosynthesis protein n=3 Tax=Actinomycetales RepID=Q47R41_THEFY  E=6e-17 s/c=0.58 id=23% cov=68%
--RGLVLLSGGIDSPVAAYRMMRRGLRLDFLHFSgMPFTGPESIYKAYSLVRQLD------------RFQNGSRLYVVPFGKAQQQLRNSGAERLQIVAQRRLMLKTAEALADRLNASALVTGDALGQVSS---------QTLANITALDDAVDLPILRPLIGMDKTEIMDQARAIGTL-----------------------------------------------------
>UniRef50_Q3Z8D8(8-223:357) tRNA-specific 2-thiouridylase mnmA n=5 Tax=Dehalococcoides RepID=MNMA_DEHE1  E=9e-17 s/c=0.41 id=21% cov=71%
----MVAMSGGVDSSVAAMLLLEQGYDVAGVSLQ--LKSNNEpygngynlklINRAREVAAALGIPHYVVDLSDIFSQRVIADF--------CQQYSQGRTPNPCIRCNYYVKIGALLEKIPDFNAGYLATGHYArvlsdENGTHLLKGADEKKDQSYFLYTLPPESLSRLIFPLGKRYKKDIIRLADKMK-------------------------------------------------------
>UniRef50_D0XY41(143-350:458) Putative uncharacterized protein n=1 Tax=Caulobacter segnis ATCC 21756 RepID=D0XY41_9CAUL  E=2e-16 s/c=0.42 id=19% cov=82%
--KTIIPYSNGLDSLAVAALTSEA--------------RPSDLVRVRLGAAFADQKSH------------NKRRQAFASVPYEVRVAKGRRKESSARSRGFKFAVITGIAAVLAKADKIVVTESGqgalgpvltvsGQAYPDYRVHPAFTMRVERLFATLLGHSAHYDFPRLWSTKGETIAEAARATP--QPWAETRSCWQqsrqvgmGGKQRQCGVCAACMLRRMSLHAAGVVEPA------------
>UniRef50_A6DMI7(198-372:433) Putative uncharacterized protein n=1 Tax=Lentisphaera araneosa HTCC2155 RepID=A6DMI7_9BACT  E=2e-16 s/c=0.50 id=18% cov=69%
---VLCLLSGGIDSPVAAFKAMQRGSHVNSITFESFPYTQPELID--KVAK-------LQTILDKFQDHPAKFYACNMAESQKMIRDDCSERFRTILYRR-IMMRVSTVVAEHLKTKALLTGEAVGQVAS---------QTLANMDTINRATNTLVLRPLVCMDKNEVIAIAEKAGTFDV---------------------------------------------------
>UniRef50_B9ZP51(178-335:493) Thiamine biosynthesis/tRNA modification protein ThiI n=1 Tax=Thioalkalivibrio sp. K90mix RepID=B9ZP51_9GAMM  E=3e-16 s/c=0.56 id=26% cov=69%
--RAMVLISGGFDSAVAAWYIMRRGTAVDFVFCNLGGTVHEEMVLA--VCRRL-------VSDWGAGIRPRMFSVDFSGVVDDLRAKVPGDAWQIVLKR--LMYRAAEPIARERGAEALVTGEALSQVSSQTLSNLETIDA---------AADLPVLRPLIGFDKTEIMNRARAIGTFEL---------------------------------------------------
>UniRef50_B7AL92(12-185:357) Putative uncharacterized protein n=3 Tax=Bacteroides RepID=B7AL92_9BACE  E=6e-16 s/c=0.50 id=39% cov=24%
-ERVLLGMSGGTDSSVAAMRLLDAGYEVTGVTFRfYEVDGRTEyLDDARALAARLGIE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_O75648(5-248:421) Mitochondrial tRNA-specific 2-thiouridylase 1 n=19 Tax=Tetrapoda RepID=MTU1_HUMAN  E=9e-16 s/c=0.35 id=19% cov=50%
-RHVVCALSGGVDSAVAALLLRRRGYQVTGVFMKNWDsldehgvcTADKDCEDAYRVCQILDIPFHQVSYVKEYWNDVFSDFLNEYEKGRTPNPD-------IVCNKHIKFSCFFHYAVDNLGADAIATG-------------------------------------------------------------------------------------------------------------
>UniRef50_C5CIB3(4-229:359) tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase n=1 Tax=Kosmotoga olearia TBF 19.5.1 RepID=C5CIB3_KOSOT  E=8e-15 s/c=0.37 id=18% cov=71%
-----VALSGGVDSAVAAAILKAEGHDVVGYHMknlpDTLFELVPEKKKVccspsdtidtHKIAAKLGIELRIVKLNDIFRKEIIDYFIR--------EYQAGKTPNPCVRCNDLMKFGALMEKAFGDGMEKFASGHYARIVEHPKyglslaRGVAKYKDQAYFLSRIKRRKLPYIIFPNGNMTKEEIRDIARELG-------------------------------------------------------
>UniRef50_Q8EVH8(172-336:383) Probable tRNA sulfurtransferase n=1 Tax=Mycoplasma penetrans RepID=THII_MYCPE  E=1e-14 s/c=0.50 id=17% cov=68%
--RCLSLLSGGIDSPVASFLLQKRGQQVDYLTFITDDVTEITLNKLKSLIKQI---------TLNYKIYKPRFFIVDFTKVQHELIHMSNEKYRITLMRRS-FYRIAQQLAIKYKMNSLICGDSLGQVAS------QTIESINTISQVCD--KMEIFRPLLTFDKVEIIEIAKQIG-------------------------------------------------------
>UniRef50_A3CVZ2(177-335:392) Thiamine biosynthesis/tRNA modification protein ThiI n=1 Tax=Methanoculleus marisnigri JR1 RepID=A3CVZ2_METMJ  E=1e-14 s/c=0.52 id=18% cov=68%
---VMALLSEGIDSPVASWLMMRRGCLVVHVNMHGGRFGGADAEK--------NVLANHARLSLWVPGHALDLLVVEMEPFFTAITGLKEPRYRCVLCKRF-MLRVASLLATERGAAALVSGDNLGQVAS---------QTLANMAVIAPAATVPVLRPLIGFDKEEVVDRARAIG-------------------------------------------------------
>UniRef50_C8SBE2(16-162:265) ExsB family protein n=3 Tax=Archaeoglobaceae RepID=C8SBE2_FERPL   E=2e-14 s/c=0.56 id=32% cov=28%
FESVVVAFSGGVDSSTLAGLANEL-TEVLAVTIISPTTPSREIRDAERIARELNLK-HRFHELNEL---------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q0EYL6(179-338:392) Putative uncharacterized protein n=1 Tax=Mariprofundus ferrooxydans PV-1 RepID=Q0EYL6_9PROT  E=5e-14 s/c=0.50 id=24% cov=70%
--RGVVLFSGGIDSPVAAYSMMKRGMEVVLVHL-YNSTINRDFAKIRDLARQLSL----------YQGRLTLHMIDLEEFQRHAIAKVDAEYRMIIYKRQ--MIRSAAAIAADAGAQALVTGDSLGQVAS---------QTLANIHAIYDASDLPLLSPLIAWDKEEIIALAKRIGTYEISIEE-----------------------------------------------
>UniRef50_Q254T8(218-388:512) GMP synthase [glutamine-hydrolyzing] n=26 Tax=cellular organisms RepID=GUAA_CHLFF  E=3e-13 s/c=0.45 id=29% cov=24%
-ERVLLGLSGGVDSSVLAVLLHNAlGDRLSCVFVDTGLLRKNEVEEVKQQFLSLGLE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D2RFP8(19-163:259) ExsB family protein n=1 Tax=Archaeoglobus profundus DSM 5631 RepID=D2RFP8_ARCPR  E=1e-11 s/c=0.50 id=31% cov=28%
---VVVMFSGGVDSVTLTKLCKDVIKRVFAVTVVSEVLSKYDVEYAKSVAKEIGV-DHYILEIDLLND-------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q01ZH4(27-171:281) ExsB family protein n=2 Tax=Acidobacteria RepID=Q01ZH4_SOLUE   E=2e-11 s/c=0.50 id=23% cov=49%
MERVLVAFSGGTDSAYLAWAARQvLGENAVAMTADSASLPESHKRDAEDFVRRFGIVHEYIET----------------HEFDNPEYVRND-PNRCFHCKDELFTRLAE-VGQARGYRHIVYGVNVDDLGDY----------------------------------------------------------------------------------------------------
>UniRef50_Q311J6(65-218:362) Putative uncharacterized protein n=1 Tax=Desulfovibrio desulfuricans subsp. desulfuricans str. G20 RepID=Q311J6_DESDG  E=1e-10 s/c=0.45 id=22% cov=23%
--DAILMMSGGKDSAYLAWLLKEKyGLTILALTIDNNFEYEETFERASELCKTLDI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C0QBA2(17-172:276) ATP-utilizing protein of the PP-loop superfamily n=1 Tax=Desulfobacterium autotrophicum HRM2 RepID=C0QBA2_DESAH  E=3e-10 s/c=0.43 id=19% cov=48%
--KIAIAFSGGVDSAFLAAVAKDTCGSSVAITVKSAFQSGQEAYNAVCMAEAIGIRHVVV-----------------QADVLGNSRIVKNTSERCYFCKKMIF-SLLTDRADELGLKTIVHGANVDDLADY----------------------------------------------------------------------------------------------------
>UniRef50_Q469Z8(3-168:395) Argininosuccinate synthase n=16 Tax=Euryarchaeota RepID=ASSY_METBF   E=3e-10 s/c=0.41 id=19% cov=71%
-KKVALAYSGGLDTSVCIPILKEKygYDEVVTISVDVGQ-PEEEIKRADAKAEKISNKHYTIDAKEEFVK-------DYVFPLIKANGSYEGYVMGTSIARPLIAKKV-VEAARKEGAVALAHG---------CTGKGNDQLRFEAVFRQ---TDMDVIAPMREMNLTREWEI-DYAKEHGIPVEVTKS--------------------------------------------
>UniRef50_B3E103(22-170:307) tRNA(Ile)-lysidine synthase MesJ n=1 Tax=Methylacidiphilum infernorum V4 RepID=B3E103_METI4  E=3e-09 s/c=0.43 id=24% cov=23%
---VLCGISGGVDSIVLLHSLVETGKRPIVLHFQHGwrQDEESDAKLVEETAKELGVE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C7NWE7(124-334:443) Putative uncharacterized protein n=1 Tax=Halomicrobium mukohataei DSM 12286 RepID=C7NWE7_HALMD  E=3e-09 s/c=0.30 id=22% cov=81%
------LFSGGVDSLATYVRHREADPALIAiqgwvIGVDEDDRWERAMGHVDRFAKREDCPTHGVtaDISDFLDHTMLNVHYKHHTDGGWYSGVGHGIG----------LLGVCAPLAYSQGYGVVHMGSTHWDGFelesitwpgrgSPWGSHPDIDDNVRWAGTRGHHDAFDITRQ----DKLEL--LADYARETGSPFV-IRTCTYDDAGGNCNRCEKCVRTATGL---------------------
>UniRef50_A8ZUB0(5-198:207) Putative uncharacterized protein n=1 Tax=Desulfococcus oleovorans Hxd3 RepID=A8ZUB0_DESOH  E=3e-09 s/c=0.33 id=17% cov=81%
-KKILCMYSGGLDSLGVLYRLLtePEYAD-FGLHVHH--MHLKNVEN-RALAE----SKAIQATFRYFREKGYRNFLYTESGHDYSFMRRYFTFDTYWYA-----FMAANIITADSSIMHVAVGRTKSDmeSAGSRMNANRGHEIFHATLPLELRFDRSYIYPVAHLTKQAVWNM-----LPADLRELSWSCRKPvisdKEPRPCGKCPTCQE--------------------------
>UniRef50_Q1D532(31-176:298) Putative uncharacterized protein n=8 Tax=Bacteria RepID=Q1D532_MYXXD  E=3e-09 s/c=0.44 id=47% cov=25%
---ALVAFSGGVDSTFVLKVAVEElGDRALALTALSASVAPEEADEARELATRLGAR-HVVL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q0W864(50-215:308) Predicted ATPase (PP-loop superfamily) n=6 Tax=Euryarchaeota RepID=Q0W864_UNCMA  E=5e-09 s/c=0.38 id=30% cov=24%
-----VAMSGGKDSAVTLSILVdtfttRSNIKFSAITVDEGIEGYRneSIPYAKELCDRLGVPHYVV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C5Y2Y7(242-364:584) Putative uncharacterized protein Sb05g000440 n=1 Tax=Sorghum bicolor RepID=C5Y2Y7_SORBI  E=6e-09 s/c=0.52 id=33% cov=24%
-----VLLSGGLDSSLVAAVAVRHLAETEAATrwgtklhsFCVGLEGSPDLKAAREVADYLGTLHHE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_UPI0001C34D32(20-191:464) tRNA(Ile)-lysidine synthetase n=1 Tax=Clostridium sp. M62/1 RepID=UPI0001C34D32  E=7e-09 s/c=0.37 id=33% cov=23%
--RVVVGLSGGADSVCLLSLLTDmrssLSIRLRAVHVHHglrGQEADRDADFSRELCRKLDI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q034V7(16-171:436) tRNA(Ile)-lysidine synthetase, MesJ n=8 Tax=Lactobacillus RepID=Q034V7_LACC3  E=9e-09 s/c=0.40 id=34% cov=45%
--RVLVAVSGGVDSMVLLNLAVKAADlDVVVATFDHRLRPESQQEQAFVVAA---AQQLQVPVVTGQWRR------------------SDGQPTSEAAARQARYAFLAATAAEQH-AEVVMTAHHADD--------------------------------------------------------------------------------------------------------
>UniRef50_A6DA04(235-397:565) Asparagine synthase, glutamine-hydrolyzing n=1 Tax=Caminibacter mediatlanticus TB-2 RepID=A6DA04_9PROT  E=1e-08 s/c=0.38 id=29% cov=23%
------LLSGGVDSSLIVALALK-YKKIDTFSIGYeGFENYDERKYAKVVANHLGIKNF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C6A3M7(59-182:331) ATPase, PP-loop superfamily n=2 Tax=Euryarchaeota RepID=C6A3M7_THESM  E=1e-08 s/c=0.50 id=33% cov=25%
--RIAVGVSGGKDSVVLLHILHKLSqkfpFEIIAITIDEGIEGYRpeSVEIAKRNAKKLGIE-HKI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1Z0X2(20-199:272) Putative uncharacterized protein n=1 Tax=Methanocella paludicola SANAE RepID=D1Z0X2_METPS  E=2e-08 s/c=0.34 id=24% cov=64%
MGSVLVAFSGGVDSSFLLKCAVDtLGtQKVAAATAVSEILSPEDFDLAESIAKDLGVRHVIV----------------TSSEMENAEFIANTPERCYV-CKKGRFSKLIEEK-EKLSLAYIADGSNRDDEADYRPGERAMKE-------LGIRSPLR----EAQLYKSEIRELSREMG-------------------------------------------------------
>UniRef50_B9ZLZ3(1-208:239) Putative uncharacterized protein n=1 Tax=Thioalkalivibrio sp. K90mix RepID=B9ZLZ3_9GAMM  E=3e-08 s/c=0.29 id=20% cov=82%
MHTIKLLWTGGWDSSYrLLDLALYRNRKVQPIYV-LDPRRKSYVYELRAMANiRAGIEAR--AEARGRVAPVRVYLRSDILEDPNITELYQRLASEVHVGTQ---YDWLARLCEQEGLR---------DLELSLTGHEAGTELQERLFRNPQYGDFRFreddfawelfqyyRFPLLSVTKEAMKYDAEAKGFLPL-LEQSWFCHSPILGQPCGHCQPCR---------------------------
>UniRef50_B8I976(1518-1664:2142) AMP-dependent synthetase and ligase n=3 Tax=Firmicutes RepID=B8I976_CLOCE  E=5e-08 s/c=0.41 id=23% cov=23%
----LLLYSGGRGAANALYHLVDMGYNVLTITYDNGYFTKSDIENIKRITTKLGI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1VX51(25-171:448) tRNA(Ile)-lysidine synthetase n=2 Tax=Prevotella RepID=D1VX51_9BACT   E=5e-08 s/c=0.41 id=24% cov=24%
----LVALSGGADSVCLLRCLQALGYRLEAVHCHFHLRAEeadRDLSFCQDLCAKLQIPFH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q4C250(217-278:585) Asparagine synthase n=1 Tax=Crocosphaera watsonii WH 8501 RepID=Q4C250_CROWT  E=6e-08 s/c=0.97 id=22% cov=22%
-----ICLSGGLDSSIIAALLVKLGVKVRAYTLEFEKDNLSEYPYAEMVAKHLNI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A2BJ08(65-181:341) Predicted ATPase of the PP-loop superfamily n=1 Tax=Hyperthermus butylicus DSM 5456 RepID=A2BJ08_HYPBU  E=7e-08 s/c=0.51 id=28% cov=23%
--KILVAISGGKDSAVTLAalsdLAKKYGIEVYAIHLRlgFGEFSAKVEERVRSLCNMLGI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A4RU16(236-429:638) Predicted protein n=8 Tax=cellular organisms RepID=A4RU16_OSTLU   E=7e-08 s/c=0.31 id=33% cov=24%
-----VLLSGGLDSSLITSIAVRQrklakntyGAD-EPVHsFSIGIKGAPDLVAARKVAEQLGTIHHEV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B4W068(145-336:452) Putative uncharacterized protein n=3 Tax=Cyanobacteria RepID=B4W068_9CYAN  E=1e-07 s/c=0.31 id=13% cov=81%
---------GGKDSIVALKLLQEA--DIPFASMQYShtvyGKADIQHHLISGVLEHVtPIKKHKISIYDDFLDYPLLELYFPDTSGITVPETPVSIFEALPLMLNHGYNDLALAHEKSANTGNLFWDKLGKEVNHQWGKGYEAEKELNQFIQANLLSNFTYFSILQPIY---DFRIFKNLTKYPEVLPKIHSC--NIQKPWCKKCPKC----------------------------
>UniRef50_A6DR67(24-163:265) Putative uncharacterized protein n=1 Tax=Lentisphaera araneosa HTCC2155 RepID=A6DR67_9BACT  E=1e-07 s/c=0.42 id=23% cov=59%
--------SGGVDSSLLAALAYEfiSPEKVELIIADSPSIPRSELKEAKALAEE--------------RNWDLTIIYTHEIDNPNYQENSGDR----CYYCKSELFSEMSAYAKEKDIRTLAYGAILDDLS---DHRPGAKAAAEHA----------VIAPLQILSKEEIRELSRE---------------------------------------------------------
>UniRef50_C9YDI6(260-383:647) Putative uncharacterized protein n=1 Tax=Curvibacter putative symbiont of Hydra magnipapillata RepID=C9YDI6_9BURK  E=1e-07 s/c=0.48 id=30% cov=23%
-------LSGGLDSSAVVAFAREQNPDIQCYSIDVQgaqdEGFADDLPYARRVAQHLGVPLHVV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1UGP9(243-363:460) Putative uncharacterized protein n=1 Tax=Burkholderia sp. CCGE1001 RepID=D1UGP9_9BURK  E=1e-07 s/c=0.49 id=27% cov=32%
-------------------------------------------------------------------------------------------------------------------------------------CYPGFTKQLSRFLEKLTRKSIDFYHPALFQTKAQVLMQLEGHGvGLGQVLAQHWSCsydsrwaHAEHRKVHCGICGNCLLRR------------------------
>UniRef50_A8LHQ9(23-133:417) tRNA(Ile)-lysidine synthetase n=1 Tax=Dinoroseobacter shibae DFL 12 RepID=A8LHQ9_DINSH  E=1e-07 s/c=0.53 id=31% cov=24%
-RRIGVAMSGGGDSMALLHLLADwaaqSGAELRAASVDHGLRPEaaDEIALAAKTCAALGI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A2BKK3(245-309:660) Phosphoadenosine 5'-phosphosulfate reductase n=1 Tax=Hyperthermus butylicus DSM 5456 RepID=A2BKK3_HYPBU  E=1e-07 s/c=0.91 id=31% cov=23%
--DVMVAVSGGKDSTVAAALAVKAGLR-RAYFFDTGIEFPETIETAHRVAQTLG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D2QWZ5(283-359:647) Asparagine synthase (Glutamine-hydrolyzing) n=3 Tax=Planctomycetaceae RepID=D2QWZ5_9PLAN  E=1e-07 s/c=0.76 id=26% cov=23%
-------LSGGIDSSLIVALMQQHStSPVKTFTIGFPMKDFDEREPAALVAKHLGTEHHLL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C9NMI3(232-358:547) Asparagine synthetase [glutamine-hydrolyzing] n=1 Tax=Vibrio coralliilyticus ATCC BAA-450 RepID=C9NMI3_9VIBR  E=1e-07 s/c=0.46 id=26% cov=25%
-----LLLSGGLDSSIIASVAQkiRRSKGLNPLHsFAVGLKNSPDLKAAREVANSIGTIHHEVI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A0Q7S4(271-321:630) Glutamine amidotransferase/asparagine synthase n=15 Tax=Francisella RepID=A0Q7S4_FRATN  E=2e-06 s/c=1.09 id=27% cov=21%
-------LSGGIDSTTVVALMQSMSKnKINTFSIGFNQKEYNEAEHARAVAKHIG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C1E2C8(22-96:204) Predicted protein (Fragment) n=2 Tax=Micromonas RepID=C1E2C8_9CHLO  E=2e-06 s/c=0.74 id=32% cov=25%
--RVVLCVSGGVDSVALLHLMVELrqewALDLHILHFNHGKRAESreEEAFVKDLGAKLGVEVH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_UPI0001C42099(153-386:386) hypothetical protein mru_1475 n=1 Tax=Methanobrevibacter ruminantium M1 RepID=UPI0001C42099  E=2e-06 s/c=0.24 id=16% cov=81%
---AIVALSGGTDSSFSLILAKKLGFNPIAVTVDPGTivLPNQFKYNIDKLTSKLDVKHEYIPVA--YDDIIEDSLAGRFHPCGRCSKRIEETLFKYAVDNDIPMVIFGDMLSTGSQCiTEQFYGENSEDSvsqdledSVSSDLEDSFNTELEDSINHklirlnlpaalavsklenkaltshyelnkfkgfGCPLLYEVHKKFPHMKKYSIQRILREtrssALEPGEALDLIWSFYK-----------------------------------------
>UniRef50_A7BBN1(42-92:369) Putative uncharacterized protein n=1 Tax=Actinomyces odontolyticus ATCC 17982 RepID=A7BBN1_9ACTO  E=1e-05 s/c=1.03 id=35% cov=21%
----VVGLSGGADSLALALttidVAARAGIPVVTVTVDHGLRAGSG-EEARRVADR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6CXW4(20-165:273) Putative uncharacterized protein n=1 Tax=Vibrio shilonii AK1 RepID=A6CXW4_9VIBR  E=3e-05 s/c=0.35 id=20% cov=61%
--KVTVAVSGGVDSMTLAFVAHRvLGANAKMVHSISPAVPPQDTQRIEDFATRYG----------------WNMMFVESGEIDTPNY-QSNPVNRCYYCKSCLYTTLG-----SLSFGQVVSGTNLDDL---DDYRPGLIAAKEH----------RVVHPFVDASinKQDIRDIANQLG-------------------------------------------------------
>UniRef50_B5Y901(22-126:314) tRNA(Ile)-lysidine synthase (TRNA(Ile)-lysidinesynthetase) (TRNA(Ile)-2-lysyl-cytidine synthase) n=1 Tax=Coprothermobacter proteolyticus DSM 5265 RepID=B5Y901_COPPD  E=0.0001 s/c=0.47 id=25% cov=44%
----VLAVSGGKDSMVLLHLAKRfehhLPNNVVVATLNHGIR-RDALEDVKLVVQ-------------------CAQNLEFPVIVGSLSPKSFCDENTLRSHRRAFLLDVM----DQVKADRIWTAHHADDA-------------------------------------------------------------------------------------------------------
>UniRef50_A3UGT8(1-163:427) Putative uncharacterized protein n=1 Tax=Oceanicaulis alexandrii HTCC2633 RepID=A3UGT8_9RHOB  E=0.0002 s/c=0.30 id=30% cov=26%
MTDTLALgYSGGGDSTALLHALKACFPDValHALIVDHSLRPESAEEAAdnADYARDLGAEPHIL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A1WPB2(6-63:363) Phosphoadenosine phosphosulfate reductase n=2 Tax=cellular organisms RepID=A1WPB2_VEREI  E=0.0003 s/c=0.82 id=30% cov=25%
----VISVSGGKDSTATLLIALERCRreDIIAIFCDTGNEHEQTYEYLAYLEQALDIRIHRL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C8SV31(22-154:455) tRNA(Ile)-lysidine synthetase n=1 Tax=Mesorhizobium opportunistum WSM2075 RepID=C8SV31_9RHIZ  E=0.0003 s/c=0.36 id=36% cov=23%
---AVAAVSGGSDSTALLLLLKHHLDRsapsakLLAVTIDHGlrQDSAAEAQAVAKLCAERGI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
