Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	L	R	F	S	A	N	L	S	M	L	F	G	E	Y	D	F	L	A	R	F	E	K	A	A	Q	C	G	F	R	G	V	E	F	M	F	P	Y	D	Y	D	I	E	E	L	K	H	V	L	A	S	N	K	L	E	H	T	L	H	N
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	P	A	G	D	W	A	A	G	E	R	G	I	A	C	I	P	G	R	E	E	E	F	R	D	G	V	A	A	A	I	R	Y	A	R	A	L	G	N	K	K	I	N	C	L	V	G	K	T	P	A	G	F	S	S	E	Q	I	H	A
Secondary structure
SS confidence
Disorder					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		T	L	V	E	N	L	R	Y	A	A	N	M	L	M	K	E	D	I	L	L	L	I	E	P	I	N	H	F	D	I	P	G	F	H	L	T	G	T	R	Q	A	L	K	L	I	D	D	V	G	C	C	N	L	K	I	Q	Y	D	I	Y
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		H	M	Q	R	M	E	G	E	L	T	N	T	M	T	Q	W	A	D	K	I	G	H	L	Q	I	A	D	N	P	H	R	G	E	P	G	T	G	E	I	N	Y	D	Y	L	F	K	V	I	E	N	S	D	Y	N	G	W	V	G	C	E
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.
Sequence		Y	K	P	Q	T	T	T	E	A	G	L	R	W	M	D	P	Y	R
Secondary structure
SS confidence
Disorder																	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1k77 chain A Region: 3 - 258 Aligned: 256 Modelled: 256 Confidence: 100.0% Identity: 40% Fold: TIM beta/alpha-barrel Superfamily: Xylose isomerase-like Family: Hypothetical protein YgbM (EC1530) Phyre2 PDB 3ngf chain A Region: 1 - 258 Aligned: 257 Modelled: 258 Confidence: 100.0% Identity: 46% PDB header:isomerase Chain: A: PDB Molecule:ap endonuclease, family 2; PDBTitle: crystal structure of ap endonuclease, family 2 from brucella2 melitensis Phyre2 PDB 1i60 chain A Region: 3 - 257 Aligned: 245 Modelled: 255 Confidence: 100.0% Identity: 16% Fold: TIM beta/alpha-barrel Superfamily: Xylose isomerase-like Family: IolI-like Phyre2 PDB 3kws chain B Region: 2 - 257 Aligned: 248 Modelled: 250 Confidence: 100.0% Identity: 18% PDB header:isomerase Chain: B: PDB Molecule:putative sugar isomerase; PDBTitle: crystal structure of putative sugar isomerase (yp_001305149.1) from2 parabacteroides distasonis atcc 8503 at 1.68 a resolution Phyre2 PDB 2hk1 chain D Region: 3 - 256 Aligned: 247 Modelled: 250 Confidence: 100.0% Identity: 19% PDB header:isomerase Chain: D: PDB Molecule:d-psicose 3-epimerase; PDBTitle: crystal structure of d-psicose 3-epimerase (dpease) in the presence of2 d-fructose Phyre2 PDB 3qxb chain B Region: 2 - 256 Aligned: 254 Modelled: 253 Confidence: 100.0% Identity: 12% PDB header:isomerase Chain: B: PDB Molecule:putative xylose isomerase; PDBTitle: crystal structure of a putative xylose isomerase (yp_426450.1) from2 rhodospirillum rubrum atcc 11170 at 1.90 a resolution Phyre2 PDB 2zvr chain A Region: 2 - 256 Aligned: 250 Modelled: 251 Confidence: 100.0% Identity: 20% PDB header:isomerase Chain: A: PDB Molecule:uncharacterized protein tm_0416; PDBTitle: crystal structure of a d-tagatose 3-epimerase-related2 protein from thermotoga maritima Phyre2 PDB 3cny chain A Region: 2 - 257 Aligned: 240 Modelled: 246 Confidence: 100.0% Identity: 15% PDB header:biosynthetic protein Chain: A: PDB Molecule:inositol catabolism protein iole; PDBTitle: crystal structure of a putative inositol catabolism protein iole2 (iole, lp_3607) from lactobacillus plantarum wcfs1 at 1.85 a3 resolution Phyre2 PDB 3ktc chain B Region: 3 - 257 Aligned: 252 Modelled: 253 Confidence: 100.0% Identity: 15% PDB header:isomerase Chain: B: PDB Molecule:xylose isomerase; PDBTitle: crystal structure of putative sugar isomerase (yp_050048.1) from2 erwinia carotovora atroseptica scri1043 at 1.54 a resolution Phyre2 PDB 2ou4 chain C Region: 3 - 256 Aligned: 247 Modelled: 249 Confidence: 100.0% Identity: 20% PDB header:isomerase Chain: C: PDB Molecule:d-tagatose 3-epimerase; PDBTitle: crystal structure of d-tagatose 3-epimerase from2 pseudomonas cichorii Phyre2 PDB 2zds chain B Region: 4 - 257 Aligned: 248 Modelled: 254 Confidence: 100.0% Identity: 16% PDB header:dna binding protein Chain: B: PDB Molecule:putative dna-binding protein; PDBTitle: crystal structure of sco6571 from streptomyces coelicolor2 a3(2) Phyre2 PDB 3dx5 chain A Region: 3 - 256 Aligned: 237 Modelled: 251 Confidence: 100.0% Identity: 20% PDB header:lyase Chain: A: PDB Molecule:uncharacterized protein asbf; PDBTitle: crystal structure of the probable 3-dhs dehydratase asbf involved in2 the petrobactin synthesis from bacillus anthracis Phyre2 PDB 3ju2 chain A Region: 1 - 257 Aligned: 250 Modelled: 257 Confidence: 100.0% Identity: 17% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein smc04130; PDBTitle: crystal structure of protein smc04130 from sinorhizobium meliloti 1021 Phyre2 PDB 2qw5 chain B Region: 16 - 256 Aligned: 236 Modelled: 241 Confidence: 100.0% Identity: 19% PDB header:isomerase Chain: B: PDB Molecule:xylose isomerase-like tim barrel; PDBTitle: crystal structure of a putative sugar phosphate isomerase/epimerase2 (ava4194) from anabaena variabilis atcc 29413 at 1.78 a resolution Phyre2 PDB 2g0w chain A domain 1 Region: 2 - 257 Aligned: 234 Modelled: 256 Confidence: 100.0% Identity: 20% Fold: TIM beta/alpha-barrel Superfamily: Xylose isomerase-like Family: IolI-like Phyre2 PDB 3cqk chain B Region: 2 - 257 Aligned: 248 Modelled: 256 Confidence: 100.0% Identity: 15% PDB header:isomerase Chain: B: PDB Molecule:l-ribulose-5-phosphate 3-epimerase ulae; PDBTitle: crystal structure of l-xylulose-5-phosphate 3-epimerase ulae (form b)2 complex with zn2+ and sulfate Phyre2 PDB 3l23 chain A Region: 2 - 256 Aligned: 248 Modelled: 255 Confidence: 100.0% Identity: 14% PDB header:isomerase Chain: A: PDB Molecule:sugar phosphate isomerase/epimerase; PDBTitle: crystal structure of sugar phosphate isomerase/epimerase2 (yp_001303399.1) from parabacteroides distasonis atcc 8503 at 1.70 a3 resolution Phyre2 PDB 3obe chain B Region: 2 - 258 Aligned: 243 Modelled: 252 Confidence: 100.0% Identity: 14% PDB header:isomerase Chain: B: PDB Molecule:sugar phosphate isomerase/epimerase; PDBTitle: crystal structure of a sugar phosphate isomerase/epimerase (bdi_3400)2 from parabacteroides distasonis atcc 8503 at 1.70 a resolution Phyre2 PDB 2q02 chain A domain 1 Region: 3 - 256 Aligned: 235 Modelled: 254 Confidence: 100.0% Identity: 17% Fold: TIM beta/alpha-barrel Superfamily: Xylose isomerase-like Family: IolI-like Phyre2 PDB 3lmz chain A Region: 2 - 256 Aligned: 218 Modelled: 222 Confidence: 100.0% Identity: 14% PDB header:isomerase Chain: A: PDB Molecule:putative sugar isomerase; PDBTitle: crystal structure of putative sugar isomerase. (yp_001305105.1) from2 parabacteroides distasonis atcc 8503 at 1.44 a resolution Phyre2 1 d1k77a_ 2 c3ngfA_ 3 d1i60a_ 4 c3kwsB_ 5 c2hk1D_ 6 c3qxbB_ 7 c2zvrA_ 8 c3cnyA_ 9 c3ktcB_ 10 c2ou4C_ 11 c2zdsB_ 12 c3dx5A_ 13 c3ju2A_ 14 c2qw5B_ 15 d2g0wa1 16 c3cqkB_ 17 c3l23A_ 18 c3obeB_ 19 d2q02a1 20 c3lmzA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1k77a_ 100.0 40 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Hypothetical protein YgbM (EC1530) 2 c3ngfA_ 100.0 46 PDB header:isomerase Chain: A: PDB Molecule:ap endonuclease, family 2; PDBTitle: crystal structure of ap endonuclease, family 2 from brucella2 melitensis 3 d1i60a_ 100.0 16 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:IolI-like 4 c3kwsB_ 100.0 18 PDB header:isomerase Chain: B: PDB Molecule:putative sugar isomerase; PDBTitle: crystal structure of putative sugar isomerase (yp_001305149.1) from2 parabacteroides distasonis atcc 8503 at 1.68 a resolution 5 c2hk1D_ 100.0 19 PDB header:isomerase Chain: D: PDB Molecule:d-psicose 3-epimerase; PDBTitle: crystal structure of d-psicose 3-epimerase (dpease) in the presence of2 d-fructose 6 c3qxbB_ 100.0 12 PDB header:isomerase Chain: B: PDB Molecule:putative xylose isomerase; PDBTitle: crystal structure of a putative xylose isomerase (yp_426450.1) from2 rhodospirillum rubrum atcc 11170 at 1.90 a resolution 7 c2zvrA_ 100.0 20 PDB header:isomerase Chain: A: PDB Molecule:uncharacterized protein tm_0416; PDBTitle: crystal structure of a d-tagatose 3-epimerase-related2 protein from thermotoga maritima 8 c3cnyA_ 100.0 15 PDB header:biosynthetic protein Chain: A: PDB Molecule:inositol catabolism protein iole; PDBTitle: crystal structure of a putative inositol catabolism protein iole2 (iole, lp_3607) from lactobacillus plantarum wcfs1 at 1.85 a3 resolution 9 c3ktcB_ 100.0 15 PDB header:isomerase Chain: B: PDB Molecule:xylose isomerase; PDBTitle: crystal structure of putative sugar isomerase (yp_050048.1) from2 erwinia carotovora atroseptica scri1043 at 1.54 a resolution 10 c2ou4C_ 100.0 20 PDB header:isomerase Chain: C: PDB Molecule:d-tagatose 3-epimerase; PDBTitle: crystal structure of d-tagatose 3-epimerase from2 pseudomonas cichorii 11 c2zdsB_ 100.0 16 PDB header:dna binding protein Chain: B: PDB Molecule:putative dna-binding protein; PDBTitle: crystal structure of sco6571 from streptomyces coelicolor2 a3(2) 12 c3dx5A_ 100.0 20 PDB header:lyase Chain: A: PDB Molecule:uncharacterized protein asbf; PDBTitle: crystal structure of the probable 3-dhs dehydratase asbf involved in2 the petrobactin synthesis from bacillus anthracis 13 c3ju2A_ 100.0 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein smc04130; PDBTitle: crystal structure of protein smc04130 from sinorhizobium meliloti 1021 14 c2qw5B_ 100.0 19 PDB header:isomerase Chain: B: PDB Molecule:xylose isomerase-like tim barrel; PDBTitle: crystal structure of a putative sugar phosphate isomerase/epimerase2 (ava4194) from anabaena variabilis atcc 29413 at 1.78 a resolution 15 d2g0wa1 100.0 20 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:IolI-like 16 c3cqkB_ 100.0 15 PDB header:isomerase Chain: B: PDB Molecule:l-ribulose-5-phosphate 3-epimerase ulae; PDBTitle: crystal structure of l-xylulose-5-phosphate 3-epimerase ulae (form b)2 complex with zn2+ and sulfate 17 c3l23A_ 100.0 14 PDB header:isomerase Chain: A: PDB Molecule:sugar phosphate isomerase/epimerase; PDBTitle: crystal structure of sugar phosphate isomerase/epimerase2 (yp_001303399.1) from parabacteroides distasonis atcc 8503 at 1.70 a3 resolution 18 c3obeB_ 100.0 14 PDB header:isomerase Chain: B: PDB Molecule:sugar phosphate isomerase/epimerase; PDBTitle: crystal structure of a sugar phosphate isomerase/epimerase (bdi_3400)2 from parabacteroides distasonis atcc 8503 at 1.70 a resolution 19 d2q02a1 100.0 17 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:IolI-like 20 c3lmzA_ 100.0 14 PDB header:isomerase Chain: A: PDB Molecule:putative sugar isomerase; PDBTitle: crystal structure of putative sugar isomerase. (yp_001305105.1) from2 parabacteroides distasonis atcc 8503 at 1.44 a resolution 21 d1xp3a1 not modelled 100.0 18 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Endonuclease IV 22 c3p6lA_ not modelled 100.0 18 PDB header:isomerase Chain: A: PDB Molecule:sugar phosphate isomerase/epimerase; PDBTitle: crystal structure of a sugar phosphate isomerase/epimerase (bdi_1903)2 from parabacteroides distasonis atcc 8503 at 1.85 a resolution 23 d1qtwa_ not modelled 100.0 16 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Endonuclease IV 24 c2x7vA_ not modelled 100.0 14 PDB header:hydrolase Chain: A: PDB Molecule:probable endonuclease 4; PDBTitle: crystal structure of thermotoga maritima endonuclease iv in2 the presence of zinc 25 d1muwa_ not modelled 100.0 19 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 26 d1qt1a_ not modelled 100.0 18 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 27 d2glka1 not modelled 100.0 19 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 28 d1yx1a1 not modelled 100.0 16 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:KguE-like 29 d1bxba_ not modelled 100.0 16 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 30 d1bxca_ not modelled 100.0 16 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 31 d1xima_ not modelled 100.0 19 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 32 d1tz9a_ not modelled 100.0 16 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:UxuA-like 33 c3aamA_ not modelled 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:endonuclease iv; PDBTitle: crystal structure of endonuclease iv from thermus thermophilus hb8 34 d1xlma_ not modelled 100.0 17 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 35 c3bdkB_ not modelled 99.9 16 PDB header:lyase Chain: B: PDB Molecule:d-mannonate dehydratase; PDBTitle: crystal structure of streptococcus suis mannonate2 dehydratase complexed with substrate analogue 36 c2i56A_ not modelled 99.8 14 PDB header:isomerase, metal-binding protein Chain: A: PDB Molecule:l-rhamnose isomerase; PDBTitle: crystal structure of l-rhamnose isomerase from pseudomonas2 stutzeri with l-rhamnose 37 d1a0ea_ not modelled 99.8 16 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 38 d1a0da_ not modelled 99.8 14 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 39 d1a0ca_ not modelled 99.8 15 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 40 c3bzjA_ not modelled 99.6 16 PDB header:hydrolase Chain: A: PDB Molecule:uv endonuclease; PDBTitle: uvde k229l 41 c3bwwA_ not modelled 98.5 11 PDB header:metal binding protein Chain: A: PDB Molecule:protein of unknown function duf692/cog3220; PDBTitle: crystal structure of a duf692 family protein (hs_1138) from2 haemophilus somnus 129pt at 2.20 a resolution 42 d1d8wa_ not modelled 98.2 13 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:L-rhamnose isomerase 43 c3p14C_ not modelled 97.7 14 PDB header:isomerase Chain: C: PDB Molecule:l-rhamnose isomerase; PDBTitle: crystal structure of l-rhamnose isomerase with a novel high thermo-2 stability from bacillus halodurans 44 c2ftpA_ not modelled 97.7 11 PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of hydroxymethylglutaryl-coa lyase from pseudomonas2 aeruginosa 45 c3ivuB_ not modelled 97.3 12 PDB header:transferase Chain: B: PDB Molecule:homocitrate synthase, mitochondrial; PDBTitle: homocitrate synthase lys4 bound to 2-og 46 c1rr2A_ not modelled 97.3 10 PDB header:transferase Chain: A: PDB Molecule:transcarboxylase 5s subunit; PDBTitle: propionibacterium shermanii transcarboxylase 5s subunit bound to 2-2 ketobutyric acid 47 c2nx9B_ not modelled 97.1 14 PDB header:lyase Chain: B: PDB Molecule:oxaloacetate decarboxylase 2, subunit alpha; PDBTitle: crystal structure of the carboxyltransferase domain of the2 oxaloacetate decarboxylase na+ pump from vibrio cholerae 48 c3ewbX_ not modelled 96.9 12 PDB header:transferase Chain: X: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of n-terminal domain of putative 2-2 isopropylmalate synthase from listeria monocytogenes 49 c3bg3B_ not modelled 96.7 10 PDB header:ligase Chain: B: PDB Molecule:pyruvate carboxylase, mitochondrial; PDBTitle: crystal structure of human pyruvate carboxylase (missing2 the biotin carboxylase domain at the n-terminus) 50 c1ydnA_ not modelled 96.6 14 PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of the hmg-coa lyase from brucella melitensis,2 northeast structural genomics target lr35. 51 c3bleA_ not modelled 96.6 8 PDB header:transferase Chain: A: PDB Molecule:citramalate synthase from leptospira interrogans; PDBTitle: crystal structure of the catalytic domain of licms in2 complexed with malonate 52 d1nvma2 not modelled 96.5 13 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:HMGL-like 53 c1ydoC_ not modelled 96.5 14 PDB header:lyase Chain: C: PDB Molecule:hmg-coa lyase; PDBTitle: crystal structure of the bacillis subtilis hmg-coa lyase, northeast2 structural genomics target sr181. 54 c2cw6B_ not modelled 96.4 11 PDB header:lyase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria 55 c2zyfA_ not modelled 96.4 12 PDB header:transferase Chain: A: PDB Molecule:homocitrate synthase; PDBTitle: crystal structure of homocitrate synthase from thermus thermophilus2 complexed with magnesuim ion and alpha-ketoglutarate 56 c3gk0H_ not modelled 95.9 25 PDB header:transferase Chain: H: PDB Molecule:pyridoxine 5'-phosphate synthase; PDBTitle: crystal structure of pyridoxal phosphate biosynthetic2 protein from burkholderia pseudomallei 57 c1nvmG_ not modelled 95.5 13 PDB header:lyase/oxidoreductase Chain: G: PDB Molecule:4-hydroxy-2-oxovalerate aldolase; PDBTitle: crystal structure of a bifunctional aldolase-dehydrogenase :2 sequestering a reactive and volatile intermediate 58 d1m5wa_ not modelled 95.3 18 Fold:TIM beta/alpha-barrel Superfamily:Pyridoxine 5'-phosphate synthase Family:Pyridoxine 5'-phosphate synthase 59 d1h1ya_ not modelled 95.3 9 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 60 c3iwpK_ not modelled 95.2 14 PDB header:metal binding protein Chain: K: PDB Molecule:copper homeostasis protein cutc homolog; PDBTitle: crystal structure of human copper homeostasis protein cutc 61 c3hf3A_ not modelled 95.1 18 PDB header:oxidoreductase Chain: A: PDB Molecule:chromate reductase; PDBTitle: old yellow enzyme from thermus scotoductus sa-01 62 c3eegB_ not modelled 95.1 11 PDB header:transferase Chain: B: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of a 2-isopropylmalate synthase from2 cytophaga hutchinsonii 63 c2xioA_ not modelled 94.7 9 PDB header:hydrolase Chain: A: PDB Molecule:putative deoxyribonuclease tatdn1; PDBTitle: structure of putative deoxyribonuclease tatdn1 isoform a 64 d1sr9a2 not modelled 94.4 11 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:HMGL-like 65 c2zq0B_ not modelled 94.3 16 PDB header:hydrolase Chain: B: PDB Molecule:alpha-glucosidase (alpha-glucosidase susb); PDBTitle: crystal structure of susb complexed with acarbose 66 c3noyA_ not modelled 94.2 12 PDB header:oxidoreductase Chain: A: PDB Molecule:4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; PDBTitle: crystal structure of ispg (gcpe) 67 c2h90A_ not modelled 93.8 15 PDB header:oxidoreductase Chain: A: PDB Molecule:xenobiotic reductase a; PDBTitle: xenobiotic reductase a in complex with coumarin 68 d1rpxa_ not modelled 93.4 10 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 69 d1ps9a1 not modelled 93.4 16 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 70 c1ps9A_ not modelled 92.9 16 PDB header:oxidoreductase Chain: A: PDB Molecule:2,4-dienoyl-coa reductase; PDBTitle: the crystal structure and reaction mechanism of e. coli 2,4-2 dienoyl coa reductase 71 d1uuqa_ not modelled 92.7 23 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-glycanases 72 c1uz4A_ not modelled 92.7 23 PDB header:hydrolase Chain: A: PDB Molecule:man5a; PDBTitle: common inhibition of beta-glucosidase and beta-mannosidase2 by isofagomine lactam reflects different conformational3 intineraries for glucoside and mannoside hydrolysis 73 c3a24A_ not modelled 92.7 19 PDB header:hydrolase Chain: A: PDB Molecule:alpha-galactosidase; PDBTitle: crystal structure of bt1871 retaining glycosidase 74 c3b0vD_ not modelled 92.4 10 PDB header:oxidoreductase/rna Chain: D: PDB Molecule:trna-dihydrouridine synthase; PDBTitle: trna-dihydrouridine synthase from thermus thermophilus in complex with2 trna 75 d1z41a1 not modelled 92.1 17 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 76 d1twda_ not modelled 91.6 13 Fold:TIM beta/alpha-barrel Superfamily:CutC-like Family:CutC-like 77 d1qopa_ not modelled 91.0 13 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 78 c1sr9A_ not modelled 90.9 11 PDB header:transferase Chain: A: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of leua from mycobacterium tuberculosis 79 c3ncoA_ not modelled 90.7 13 PDB header:hydrolase Chain: A: PDB Molecule:endoglucanase fncel5a; PDBTitle: crystal structure of fncel5a from f. nodosum rt17-b1 80 c2vg2C_ not modelled 90.5 12 PDB header:transferase Chain: C: PDB Molecule:undecaprenyl pyrophosphate synthetase; PDBTitle: rv2361 with ipp 81 c3thaB_ not modelled 90.1 16 PDB header:lyase Chain: B: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: tryptophan synthase subunit alpha from campylobacter jejuni. 82 c3qc3B_ not modelled 89.9 7 PDB header:isomerase Chain: B: PDB Molecule:d-ribulose-5-phosphate-3-epimerase; PDBTitle: crystal structure of a d-ribulose-5-phosphate-3-epimerase (np_954699)2 from homo sapiens at 2.20 a resolution 83 c1xc6A_ not modelled 89.9 11 PDB header:hydrolase Chain: A: PDB Molecule:beta-galactosidase; PDBTitle: native structure of beta-galactosidase from penicillium sp. in complex2 with galactose 84 c3gr7A_ not modelled 89.6 19 PDB header:oxidoreductase Chain: A: PDB Molecule:nadph dehydrogenase; PDBTitle: structure of oye from geobacillus kaustophilus, hexagonal2 crystal form 85 c2bdqA_ not modelled 89.4 13 PDB header:metal transport Chain: A: PDB Molecule:copper homeostasis protein cutc; PDBTitle: crystal structure of the putative copper homeostasis2 protein cutc from streptococcus agalactiae, northeast3 strucural genomics target sar15. 86 c3ogrA_ not modelled 88.1 15 PDB header:hydrolase Chain: A: PDB Molecule:beta-galactosidase; PDBTitle: complex structure of beta-galactosidase from trichoderma reesei with2 galactose 87 d2c0ha1 not modelled 87.8 12 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-glycanases 88 c3bg5C_ not modelled 87.7 13 PDB header:ligase Chain: C: PDB Molecule:pyruvate carboxylase; PDBTitle: crystal structure of staphylococcus aureus pyruvate2 carboxylase 89 d1gwja_ not modelled 87.6 15 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 90 c3pzqA_ not modelled 87.2 19 PDB header:hydrolase Chain: A: PDB Molecule:mannan endo-1,4-beta-mannosidase. glycosyl hydrolase family PDBTitle: structure of the hyperthermostable endo-1,4-beta-d-mannanase from2 thermotoga petrophila rku-1 with maltose and glycerol 91 d1rh9a1 not modelled 86.6 15 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-glycanases 92 c2yfnA_ not modelled 86.4 14 PDB header:hydrolase Chain: A: PDB Molecule:alpha-galactosidase-sucrose kinase agask; PDBTitle: galactosidase domain of alpha-galactosidase-sucrose kinase,2 agask 93 c3civA_ not modelled 86.4 10 PDB header:hydrolase Chain: A: PDB Molecule:endo-beta-1,4-mannanase; PDBTitle: crystal structure of the endo-beta-1,4-mannanase from2 alicyclobacillus acidocaldarius 94 c2d2rA_ not modelled 85.9 7 PDB header:transferase Chain: A: PDB Molecule:undecaprenyl pyrophosphate synthase; PDBTitle: crystal structure of helicobacter pylori undecaprenyl pyrophosphate2 synthase 95 c1wkyA_ not modelled 85.4 13 PDB header:hydrolase Chain: A: PDB Molecule:endo-beta-1,4-mannanase; PDBTitle: crystal structure of alkaline mannanase from bacillus sp. strain jamb-2 602: catalytic domain and its carbohydrate binding module 96 d1h1na_ not modelled 85.1 10 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-glycanases 97 c3hpxB_ not modelled 85.1 11 PDB header:transferase Chain: B: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of mycobacterium tuberculosis leua active site2 domain 1-425 (truncation mutant delta:426-644) 98 d1wkya2 not modelled 84.1 13 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-glycanases 99 c3icgD_ not modelled 84.0 14 PDB header:hydrolase Chain: D: PDB Molecule:endoglucanase d; PDBTitle: crystal structure of the catalytic and carbohydrate binding domain of2 endoglucanase d from clostridium cellulovorans 100 c3jugA_ not modelled 83.0 9 PDB header:hydrolase Chain: A: PDB Molecule:beta-mannanase; PDBTitle: crystal structure of endo-beta-1,4-mannanase from the alkaliphilic2 bacillus sp. n16-5 101 c3inpA_ not modelled 81.9 12 PDB header:isomerase Chain: A: PDB Molecule:d-ribulose-phosphate 3-epimerase; PDBTitle: 2.05 angstrom resolution crystal structure of d-ribulose-phosphate 3-2 epimerase from francisella tularensis. 102 c3o6cA_ not modelled 81.7 15 PDB header:transferase Chain: A: PDB Molecule:pyridoxine 5'-phosphate synthase; PDBTitle: pyridoxal phosphate biosynthetic protein pdxj from campylobacter2 jejuni 103 d1qwga_ not modelled 81.6 14 Fold:TIM beta/alpha-barrel Superfamily:(2r)-phospho-3-sulfolactate synthase ComA Family:(2r)-phospho-3-sulfolactate synthase ComA 104 d2je8a5 not modelled 81.0 11 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-glycanases 105 d1wbha1 not modelled 80.9 10 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 106 d2flia1 not modelled 80.5 12 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 107 c2gq8A_ not modelled 80.4 14 PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase, fmn-binding; PDBTitle: structure of sye1, an oye homologue from s. ondeidensis, in complex2 with p-hydroxyacetophenone 108 d1tg7a5 not modelled 80.4 11 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Glycosyl hydrolases family 35 catalytic domain 109 d1x7fa2 not modelled 79.8 16 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Outer surface protein, N-terminal domain 110 c3navB_ not modelled 79.5 15 PDB header:lyase Chain: B: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: crystal structure of an alpha subunit of tryptophan synthase from2 vibrio cholerae o1 biovar el tor str. n16961 111 c2qjhH_ not modelled 79.4 16 PDB header:lyase Chain: H: PDB Molecule:putative aldolase mj0400; PDBTitle: m. jannaschii adh synthase covalently bound to2 dihydroxyacetone phosphate 112 d1ujpa_ not modelled 78.8 18 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 113 d1d7ka2 not modelled 78.8 10 Fold:TIM beta/alpha-barrel Superfamily:PLP-binding barrel Family:Alanine racemase-like, N-terminal domain 114 c3aysA_ not modelled 78.4 15 PDB header:hydrolase Chain: A: PDB Molecule:endoglucanase; PDBTitle: gh5 endoglucanase from a ruminal fungus in complex with cellotriose 115 d1f75a_ not modelled 78.2 14 Fold:Undecaprenyl diphosphate synthase Superfamily:Undecaprenyl diphosphate synthase Family:Undecaprenyl diphosphate synthase 116 c2y8kA_ not modelled 77.6 12 PDB header:hydrolase Chain: A: PDB Molecule:carbohydrate binding family 6; PDBTitle: structure of ctgh5-cbm6, an arabinoxylan-specific xylanase. 117 d1vyra_ not modelled 77.5 13 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 118 c3btnA_ not modelled 76.9 11 PDB header:biosynthetic protein Chain: A: PDB Molecule:antizyme inhibitor 1; PDBTitle: crystal structure of antizyme inhibitor, an ornithine2 decarboxylase homologous protein 119 d1f3ta2 not modelled 75.1 10 Fold:TIM beta/alpha-barrel Superfamily:PLP-binding barrel Family:Alanine racemase-like, N-terminal domain 120 c2dh3A_ not modelled 74.9 8 PDB header:transport protein, signaling protein Chain: A: PDB Molecule:4f2 cell-surface antigen heavy chain; PDBTitle: crystal structure of human ed-4f2hc

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0