Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP08331
DateWed Jan 25 15:20:13 GMT 2012
Unique Job ID442183489e8fa2d2

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2wdfA_
Top template information
PDB header:hydrolase
Chain: A: PDB Molecule:sulfur oxidation protein soxb;
PDBTitle: termus thermophilus sulfate thiohydrolase soxb
Confidence and coverage
Confidence:100.0% Coverage: 74%
480 residues ( 74% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
548 residues ( 85%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MIKFSATLLATLIAASVNAATVDLRIMETTDLHSNMMDFDYYKDTATEKFGLVRTASLIN
Secondary structure 
SS confidence 
Disorder  ?
??????
?
?????
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  DARNEVKNSVLVDNGDLIQGSPLADYMSAKGLKAGDIHPVYKALNTLDYTVGTLGNHEFN
Secondary structure 
SS confidence 
Disorder 
??????
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  YGLDYLKNALAGAKFPYVNANVIDARTKQPMFTPYLIKDTEVVDKDGKKQTLKIGYIGVV
Secondary structure 
SS confidence 
Disorder 
?
?
?
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  PPQIMGWDKANLSGKVTVNDITETVRKYVPEMREKGADVVVVLAHSGLSADPYKVMAENS
Secondary structure 
SS confidence 
Disorder 
?
?????????
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  VYYLSEIPGVNAIMFGHAHAVFPGKDFADIEGADIAKGTLNGVPAVMPGMWGDHLGVVDL
Secondary structure 
SS confidence 
Disorder 
?????
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  QLSNDSGKWQVTQAKAEARPIYDIANKKSLAAEDSKLVETLKADHDATRQFVSKPIGKSA
Secondary structure 
SS confidence 
Disorder 
????
Disorder confidence 
 
   .........370.........380.........390.........400.........410.........420
Sequence  DNMYSYLALVQDDPTVQVVNNAQKAYVEHYIQGDPDLAKLPVLSAAAPFKVGGRKNDPAS
Secondary structure 
SS confidence 
Disorder 
?
?
?
Disorder confidence 
 
   .........430.........440.........450.........460.........470.........480
Sequence  YVEVEKGQLTFRNAADLYLYPNTLIVVKASGKEVKEWLECSAGQFNQIDPNSTKPQSLIN
Secondary structure 
SS confidence 
Disorder  ??
???????????
?
Disorder confidence 
 
   .........490.........500.........510.........520.........530.........540
Sequence  WDGFRTYNFDVIDGVNYQIDVTQPARYDGECQMINANAERIKNLTFNGKPIDPNAMFLVA
Secondary structure 
SS confidence 
Disorder  ??????
???????
?
Disorder confidence 
 
   .........550.........560.........570.........580.........590.........600
Sequence  TNNYRAYGGKFAGTGDSHIAFASPDENRSVLAAWIADESKRAGEIHPAADNNWRLAPIAG
Secondary structure 
SS confidence 
Disorder 
?????
Disorder confidence 
 
   .........610.........620.........630.........640.......
Sequence  DKKLDIRFETSPSDKAAAFIKEKGQYPMNKVATDDIGFAIYQVDLSK
Secondary structure 
SS confidence 
Disorder 
?
???
?
??
???
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2wdf chain A

3D model

Region: 19 - 603
Aligned: 480
Modelled: 531
Confidence: 100.0%
Identity: 21%
PDB header:hydrolase
Chain: A: PDB Molecule:sulfur oxidation protein soxb;
PDBTitle: termus thermophilus sulfate thiohydrolase soxb

Phyre2

PDB 3qfk chain A

3D model

Region: 23 - 595
Aligned: 495
Modelled: 523
Confidence: 100.0%
Identity: 25%
PDB header:hydrolase
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: 2.05 angstrom crystal structure of putative 5'-nucleotidase from2 staphylococcus aureus in complex with alpha-ketoglutarate

Phyre2

PDB 2z1a chain A

3D model

Region: 22 - 599
Aligned: 491
Modelled: 518
Confidence: 100.0%
Identity: 23%
PDB header:hydrolase
Chain: A: PDB Molecule:5'-nucleotidase;
PDBTitle: crystal structure of 5'-nucleotidase precursor from thermus2 thermophilus hb8

Phyre2

PDB 3zu0 chain A

3D model

Region: 21 - 595
Aligned: 502
Modelled: 525
Confidence: 100.0%
Identity: 21%
PDB header:hydrolase
Chain: A: PDB Molecule:nad nucleotidase;
PDBTitle: structure of haemophilus influenzae nad nucleotidase (nadn)

Phyre2

PDB 3ivd chain A

3D model

Region: 21 - 598
Aligned: 482
Modelled: 522
Confidence: 100.0%
Identity: 23%
PDB header:hydrolase
Chain: A: PDB Molecule:nucleotidase;
PDBTitle: putative 5'-nucleotidase (c4898) from escherichia coli in2 complex with uridine

Phyre2

PDB 1oid chain A

3D model

Region: 17 - 594
Aligned: 497
Modelled: 512
Confidence: 100.0%
Identity: 20%
PDB header:hydrolase
Chain: A: PDB Molecule:protein usha;
PDBTitle: 5'-nucleotidase (e. coli) with an engineered disulfide2 bridge (s228c, p513c)

Phyre2

PDB 3jyf chain B

3D model

Region: 19 - 353
Aligned: 335
Modelled: 335
Confidence: 100.0%
Identity: 81%
PDB header:hydrolase
Chain: B: PDB Molecule:2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-
PDBTitle: the crystal structure of a 2,3-cyclic nucleotide 2-2 phosphodiesterase/3-nucleotidase bifunctional periplasmic precursor3 protein from klebsiella pneumoniae subsp. pneumoniae mgh 78578

Phyre2

PDB 3gve chain B

3D model

Region: 20 - 354
Aligned: 329
Modelled: 335
Confidence: 100.0%
Identity: 43%
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:yfkn protein;
PDBTitle: crystal structure of calcineurin-like phosphoesterase yfkn from2 bacillus subtilis

Phyre2

PDB 3c9f chain B

3D model

Region: 23 - 546
Aligned: 460
Modelled: 495
Confidence: 100.0%
Identity: 13%
PDB header:hydrolase
Chain: B: PDB Molecule:5'-nucleotidase;
PDBTitle: crystal structure of 5'-nucleotidase from candida albicans sc5314

Phyre2

PDB 2z1a chain A domain 2

3D model

Region: 22 - 350
Aligned: 293
Modelled: 318
Confidence: 100.0%
Identity: 27%
Fold: Metallo-dependent phosphatases
Superfamily: Metallo-dependent phosphatases
Family: 5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain

Phyre2

PDB 1ush chain A domain 2

3D model

Region: 17 - 353
Aligned: 316
Modelled: 327
Confidence: 100.0%
Identity: 20%
Fold: Metallo-dependent phosphatases
Superfamily: Metallo-dependent phosphatases
Family: 5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain

Phyre2

PDB 3c9f chain A domain 2

3D model

Region: 15 - 348
Aligned: 302
Modelled: 321
Confidence: 100.0%
Identity: 16%
Fold: Metallo-dependent phosphatases
Superfamily: Metallo-dependent phosphatases
Family: 5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain

Phyre2

PDB 2z1a chain A domain 1

3D model

Region: 352 - 599
Aligned: 194
Modelled: 210
Confidence: 100.0%
Identity: 19%
Fold: 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
Superfamily: 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
Family: 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain

Phyre2

PDB 1ush chain A domain 1

3D model

Region: 356 - 594
Aligned: 183
Modelled: 183
Confidence: 100.0%
Identity: 20%
Fold: 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
Superfamily: 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
Family: 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain

Phyre2

PDB 1t71 chain A

3D model

Region: 23 - 295
Aligned: 209
Modelled: 246
Confidence: 100.0%
Identity: 15%
Fold: Metallo-dependent phosphatases
Superfamily: Metallo-dependent phosphatases
Family: DR1281-like

Phyre2

PDB 1t70 chain A

3D model

Region: 24 - 297
Aligned: 202
Modelled: 233
Confidence: 100.0%
Identity: 19%
Fold: Metallo-dependent phosphatases
Superfamily: Metallo-dependent phosphatases
Family: DR1281-like

Phyre2

PDB 2z06 chain A domain 1

3D model

Region: 24 - 298
Aligned: 198
Modelled: 234
Confidence: 100.0%
Identity: 18%
Fold: Metallo-dependent phosphatases
Superfamily: Metallo-dependent phosphatases
Family: TTHA0625-like

Phyre2

PDB 3c9f chain A domain 1

3D model

Region: 353 - 578
Aligned: 191
Modelled: 191
Confidence: 99.8%
Identity: 9%
Fold: 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
Superfamily: 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
Family: 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain

Phyre2

PDB 1ii7 chain A

3D model

Region: 24 - 290
Aligned: 221
Modelled: 229
Confidence: 99.5%
Identity: 18%
Fold: Metallo-dependent phosphatases
Superfamily: Metallo-dependent phosphatases
Family: DNA double-strand break repair nuclease

Phyre2

PDB 1uf3 chain A

3D model

Region: 25 - 300
Aligned: 209
Modelled: 234
Confidence: 99.4%
Identity: 13%
Fold: Metallo-dependent phosphatases
Superfamily: Metallo-dependent phosphatases
Family: TT1561-like

Phyre2
1
c2wdfA_
2
c3qfkA_
3
c2z1aA_
4
c3zu0A_
5
c3ivdA_
6
c1oidA_
7
c3jyfB_
8
c3gveB_
9
c3c9fB_
10
d2z1aa2
11
d1usha2
12
d3c9fa2
13
d2z1aa1
14
d1usha1
15
d1t71a_
16
d1t70a_
17
d2z06a1
18
d3c9fa1
19
d1ii7a_
20
d1uf3a_
21
22
23
24
25
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28
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2wdfA_
100.0 21 PDB header:hydrolase
Chain: A: PDB Molecule:sulfur oxidation protein soxb;
PDBTitle: termus thermophilus sulfate thiohydrolase soxb
2c3qfkA_
100.0 25 PDB header:hydrolase
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: 2.05 angstrom crystal structure of putative 5'-nucleotidase from2 staphylococcus aureus in complex with alpha-ketoglutarate
3c2z1aA_
100.0 23 PDB header:hydrolase
Chain: A: PDB Molecule:5'-nucleotidase;
PDBTitle: crystal structure of 5'-nucleotidase precursor from thermus2 thermophilus hb8
4c3zu0A_
100.0 21 PDB header:hydrolase
Chain: A: PDB Molecule:nad nucleotidase;
PDBTitle: structure of haemophilus influenzae nad nucleotidase (nadn)
5c3ivdA_
100.0 23 PDB header:hydrolase
Chain: A: PDB Molecule:nucleotidase;
PDBTitle: putative 5'-nucleotidase (c4898) from escherichia coli in2 complex with uridine
6c1oidA_
100.0 20 PDB header:hydrolase
Chain: A: PDB Molecule:protein usha;
PDBTitle: 5'-nucleotidase (e. coli) with an engineered disulfide2 bridge (s228c, p513c)
7c3jyfB_
100.0 81 PDB header:hydrolase
Chain: B: PDB Molecule:2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-
PDBTitle: the crystal structure of a 2,3-cyclic nucleotide 2-2 phosphodiesterase/3-nucleotidase bifunctional periplasmic precursor3 protein from klebsiella pneumoniae subsp. pneumoniae mgh 78578
8c3gveB_
100.0 43 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:yfkn protein;
PDBTitle: crystal structure of calcineurin-like phosphoesterase yfkn from2 bacillus subtilis
9c3c9fB_
100.0 13 PDB header:hydrolase
Chain: B: PDB Molecule:5'-nucleotidase;
PDBTitle: crystal structure of 5'-nucleotidase from candida albicans sc5314
10d2z1aa2
100.0 27 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain
11d1usha2
100.0 20 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain
12d3c9fa2
100.0 16 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain
13d2z1aa1
100.0 19 Fold:5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
Superfamily:5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
Family:5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
14d1usha1
100.0 20 Fold:5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
Superfamily:5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
Family:5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
15d1t71a_
100.0 15 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:DR1281-like
16d1t70a_
100.0 19 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:DR1281-like
17d2z06a1
100.0 18 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:TTHA0625-like
18d3c9fa1
99.8 9 Fold:5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
Superfamily:5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
Family:5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
19d1ii7a_
99.5 18 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:DNA double-strand break repair nuclease
20d1uf3a_
99.4 13 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:TT1561-like
21c2xmoB_
not modelled 99.3 14 PDB header:hydrolase
Chain: B: PDB Molecule:lmo2642 protein;
PDBTitle: the crystal structure of lmo2642
22d2yvta1
not modelled 99.2 14 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:TT1561-like
23c3auzA_
not modelled 99.2 17 PDB header:recombination
Chain: A: PDB Molecule:dna double-strand break repair protein mre11;
PDBTitle: crystal structure of mre11 with manganese
24c3ib7A_
not modelled 99.2 18 PDB header:hydrolase
Chain: A: PDB Molecule:icc protein;
PDBTitle: crystal structure of full length rv0805
25c3t1iC_
not modelled 99.1 19 PDB header:hydrolase
Chain: C: PDB Molecule:double-strand break repair protein mre11a;
PDBTitle: crystal structure of human mre11: understanding tumorigenic mutations
26c3av0A_
not modelled 99.1 16 PDB header:recombination
Chain: A: PDB Molecule:dna double-strand break repair protein mre11;
PDBTitle: crystal structure of mre11-rad50 bound to atp s
27c3qg5D_
not modelled 99.0 16 PDB header:hydrolase
Chain: D: PDB Molecule:mre11;
PDBTitle: the mre11:rad50 complex forms an atp dependent molecular clamp in dna2 double-strand break repair
28d1utea_
not modelled 98.8 13 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:Purple acid phosphatase-like
29d3d03a1
not modelled 98.8 14 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:GpdQ-like
30d1s3la_
not modelled 98.8 23 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:YfcE-like
31c1s3mA_
not modelled 98.8 23 PDB header:phosphodiesterase
Chain: A: PDB Molecule:hypothetical protein mj0936;
PDBTitle: structural and functional characterization of a novel2 archaeal phosphodiesterase
32d2nxfa1
not modelled 98.7 14 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:ADPRibase-Mn-like
33c2hy1A_
not modelled 98.7 17 PDB header:hydrolase
Chain: A: PDB Molecule:rv0805;
PDBTitle: crystal structure of rv0805
34d2hy1a1
not modelled 98.7 17 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:GpdQ-like
35c2q8uA_
not modelled 98.6 15 PDB header:hydrolase
Chain: A: PDB Molecule:exonuclease, putative;
PDBTitle: crystal structure of mre11 from thermotoga maritima msb8 (tm1635) at2 2.20 a resolution
36d1qhwa_
not modelled 98.6 12 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:Purple acid phosphatase-like
37c1qhwA_
not modelled 98.6 12 PDB header:hydrolase
Chain: A: PDB Molecule:protein (purple acid phosphatase);
PDBTitle: purple acid phosphatase from rat bone
38c1kbpB_
not modelled 98.5 15 PDB header:hydrolase (phosphoric monoester)
Chain: B: PDB Molecule:purple acid phosphatase;
PDBTitle: kidney bean purple acid phosphatase
39d2qfra2
not modelled 98.5 15 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:Purple acid phosphatase-like
40c3qfnA_
not modelled 98.4 21 PDB header:hydrolase
Chain: A: PDB Molecule:putative uncharacterized protein;
PDBTitle: crystal structure of streptococcal asymmetric ap4a hydrolase and2 phosphodiesterase spr1479/saph in complex with inorganic phosphate
41c1xzwB_
not modelled 98.4 13 PDB header:hydrolase
Chain: B: PDB Molecule:purple acid phosphatase;
PDBTitle: sweet potato purple acid phosphatase/phosphate complex
42d3ck2a1
not modelled 98.3 20 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:YfcE-like
43d1xzwa2
not modelled 98.3 13 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:Purple acid phosphatase-like
44c3rl4A_
not modelled 98.2 15 PDB header:hydrolase
Chain: A: PDB Molecule:metallophosphoesterase mpped2;
PDBTitle: rat metallophosphodiesterase mpped2 g252h mutant
45d1su1a_
not modelled 98.2 20 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:YfcE-like
46c1su1A_
not modelled 98.2 20 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein yfce;
PDBTitle: structural and biochemical characterization of yfce, a2 phosphoesterase from e. coli
47c2kknA_
not modelled 98.0 23 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: solution nmr structure of themotoga maritima protein tm1076:2 northeast structural genomics consortium target vt57
48c3rqzC_
not modelled 98.0 16 PDB header:hydrolase
Chain: C: PDB Molecule:metallophosphoesterase;
PDBTitle: crystal structure of metallophosphoesterase from sphaerobacter2 thermophilus
49d1z2wa1
not modelled 97.9 22 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:YfcE-like
50d1nnwa_
not modelled 97.9 15 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:Phosphoesterase-related
51d2a22a1
not modelled 97.9 19 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:YfcE-like
52d1xm7a_
not modelled 97.6 16 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:Hypothetical protein aq 1666
53c2qjcA_
not modelled 96.0 31 PDB header:hydrolase
Chain: A: PDB Molecule:diadenosine tetraphosphatase, putative;
PDBTitle: crystal structure of a putative diadenosine tetraphosphatase
54c2dfjA_
not modelled 95.9 30 PDB header:hydrolase
Chain: A: PDB Molecule:diadenosinetetraphosphatase;
PDBTitle: crystal structure of the diadenosine tetraphosphate2 hydrolase from shigella flexneri 2a
55d1g5ba_
not modelled 95.9 26 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:Protein serine/threonine phosphatase
56c2zbmA_
not modelled 93.9 23 PDB header:hydrolase
Chain: A: PDB Molecule:protein-tyrosine-phosphatase;
PDBTitle: crystal structure of i115m mutant cold-active protein2 tyrosine phosphatase
57c3icfB_
not modelled 88.9 21 PDB header:hydrolase
Chain: B: PDB Molecule:serine/threonine-protein phosphatase t;
PDBTitle: structure of protein serine/threonine phosphatase from saccharomyces2 cerevisiae with similarity to human phosphatase pp5
58d3c5wc1
not modelled 88.4 25 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:Protein serine/threonine phosphatase
59c3d6nB_
not modelled 87.3 16 PDB header:hydrolase/transferase
Chain: B: PDB Molecule:aspartate carbamoyltransferase;
PDBTitle: crystal structure of aquifex dihydroorotase activated by aspartate2 transcarbamoylase
60d1jk7a_
not modelled 86.1 22 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:Protein serine/threonine phosphatase
61c2jogA_
not modelled 83.6 28 PDB header:hydrolase
Chain: A: PDB Molecule:calmodulin-dependent calcineurin a subunit alpha
PDBTitle: structure of the calcineurin-nfat complex
62d1s70a_
not modelled 82.6 21 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:Protein serine/threonine phosphatase
63c2cunA_
not modelled 82.5 23 PDB header:transferase
Chain: A: PDB Molecule:phosphoglycerate kinase;
PDBTitle: crystal structure of phosphoglycerate kinase from pyrococcus2 horikoshii ot3
64c1vlvA_
not modelled 81.4 13 PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of ornithine carbamoyltransferase (tm1097) from2 thermotoga maritima at 2.25 a resolution
65c1a1sA_
not modelled 80.2 14 PDB header:transcarbamylase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: ornithine carbamoyltransferase from pyrococcus furiosus
66c2p2gD_
not modelled 79.8 22 PDB header:transferase
Chain: D: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of ornithine carbamoyltransferase from mycobacterium2 tuberculosis (rv1656): orthorhombic form
67c2w37A_
not modelled 79.3 13 PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase, catabolic;
PDBTitle: crystal structure of the hexameric catabolic ornithine2 transcarbamylase from lactobacillus hilgardii
68d1s95a_
not modelled 78.9 25 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:Protein serine/threonine phosphatase
69c1wao4_
not modelled 77.8 22 PDB header:hydrolase
Chain: 4: PDB Molecule:serine/threonine protein phosphatase 5;
PDBTitle: pp5 structure
70c3updA_
not modelled 77.5 14 PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: 2.9 angstrom crystal structure of ornithine carbamoyltransferase2 (argf) from vibrio vulnificus
71d1ltka_
not modelled 77.3 13 Fold:Phosphoglycerate kinase
Superfamily:Phosphoglycerate kinase
Family:Phosphoglycerate kinase
72c1fvoB_
not modelled 76.4 13 PDB header:transferase
Chain: B: PDB Molecule:ornithine transcarbamylase;
PDBTitle: crystal structure of human ornithine transcarbamylase complexed with2 carbamoyl phosphate
73d1hdia_
not modelled 73.6 21 Fold:Phosphoglycerate kinase
Superfamily:Phosphoglycerate kinase
Family:Phosphoglycerate kinase
74d1qopa_
not modelled 73.5 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
75c1ml4A_
not modelled 72.7 21 PDB header:transferase
Chain: A: PDB Molecule:aspartate transcarbamoylase;
PDBTitle: the pala-liganded aspartate transcarbamoylase catalytic subunit from2 pyrococcus abyssi
76d1vjda_
not modelled 72.6 21 Fold:Phosphoglycerate kinase
Superfamily:Phosphoglycerate kinase
Family:Phosphoglycerate kinase
77c2at2B_
not modelled 72.5 19 PDB header:
PDB COMPND:
78c1ortD_
not modelled 71.8 16 PDB header:transferase
Chain: D: PDB Molecule:ornithine transcarbamoylase;
PDBTitle: ornithine transcarbamoylase from pseudomonas aeruginosa
79d2p6ba1
not modelled 71.4 22 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:Protein serine/threonine phosphatase
80c1zq2A_
not modelled 70.4 15 PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of n-acetyl-l-ornithine transcarbamylase2 complexed with cp
81d1vpea_
not modelled 70.2 21 Fold:Phosphoglycerate kinase
Superfamily:Phosphoglycerate kinase
Family:Phosphoglycerate kinase
82d1qpga_
not modelled 70.0 15 Fold:Phosphoglycerate kinase
Superfamily:Phosphoglycerate kinase
Family:Phosphoglycerate kinase
83c3sdsA_
not modelled 69.0 14 PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase, mitochondrial;
PDBTitle: crystal structure of a mitochondrial ornithine carbamoyltransferase2 from coccidioides immitis
84d1phpa_
not modelled 67.9 15 Fold:Phosphoglycerate kinase
Superfamily:Phosphoglycerate kinase
Family:Phosphoglycerate kinase
85c1jvnB_
not modelled 66.7 16 PDB header:transferase
Chain: B: PDB Molecule:bifunctional histidine biosynthesis protein hishf;
PDBTitle: crystal structure of imidazole glycerol phosphate synthase: a tunnel2 through a (beta/alpha)8 barrel joins two active sites
86c2rgwD_
not modelled 64.3 17 PDB header:transferase
Chain: D: PDB Molecule:aspartate carbamoyltransferase;
PDBTitle: catalytic subunit of m. jannaschii aspartate2 transcarbamoylase
87c1js1Z_
not modelled 63.0 11 PDB header:transferase
Chain: Z: PDB Molecule:transcarbamylase;
PDBTitle: crystal structure of a new transcarbamylase from the2 anaerobic bacterium bacteroides fragilis at 2.0 a3 resolution
88c2ef0A_
not modelled 62.6 22 PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of ornithine carbamoyltransferase from thermus2 thermophilus
89d1dlja3
not modelled 62.4 7 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:UDP-glucose/GDP-mannose dehydrogenase C-terminal domain
Family:UDP-glucose/GDP-mannose dehydrogenase C-terminal domain
90c2eq5D_
not modelled 62.2 14 PDB header:isomerase
Chain: D: PDB Molecule:228aa long hypothetical hydantoin racemase;
PDBTitle: crystal structure of hydantoin racemase from pyrococcus horikoshii ot3
91c2p6bC_
not modelled 62.0 21 PDB header:hydrolase/hydrolase regulator
Chain: C: PDB Molecule:calmodulin-dependent calcineurin a subunit alpha
PDBTitle: crystal structure of human calcineurin in complex with2 pvivit peptide
92c2pjuD_
not modelled 61.0 16 PDB header:transcription
Chain: D: PDB Molecule:propionate catabolism operon regulatory protein;
PDBTitle: crystal structure of propionate catabolism operon2 regulatory protein prpr
93c3q3vA_
not modelled 59.5 13 PDB header:transferase
Chain: A: PDB Molecule:phosphoglycerate kinase;
PDBTitle: crystal structure of phosphoglycerate kinase from campylobacter2 jejuni.
94d1o94c_
not modelled 58.7 15 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:ETFP subunits
95d2zdra2
not modelled 57.0 16 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:NeuB-like
96d2pjua1
not modelled 56.7 16 Fold:Chelatase-like
Superfamily:PrpR receptor domain-like
Family:PrpR receptor domain-like
97c2q5cA_
not modelled 56.4 10 PDB header:transcription
Chain: A: PDB Molecule:ntrc family transcriptional regulator;
PDBTitle: crystal structure of ntrc family transcriptional regulator from2 clostridium acetobutylicum
98d1v6sa_
not modelled 53.9 15 Fold:Phosphoglycerate kinase
Superfamily:Phosphoglycerate kinase
Family:Phosphoglycerate kinase
99c1auiA_
not modelled 53.5 24 PDB header:hydrolase
Chain: A: PDB Molecule:serine/threonine phosphatase 2b;
PDBTitle: human calcineurin heterodimer
100d1auia_
not modelled 53.5 24 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:Protein serine/threonine phosphatase
101d1vp8a_
not modelled 52.0 25 Fold:Pyruvate kinase C-terminal domain-like
Superfamily:PK C-terminal domain-like
Family:MTH1675-like
102c1pg5A_
not modelled 49.9 16 PDB header:transferase
Chain: A: PDB Molecule:aspartate carbamoyltransferase;
PDBTitle: crystal structure of the unligated (t-state) aspartate2 transcarbamoylase from the extremely thermophilic archaeon sulfolobus3 acidocaldarius
103c2otcA_
not modelled 49.9 16 PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: ornithine transcarbamoylase complexed with n-2 (phosphonacetyl)-l-ornithine
104c3gd5D_
not modelled 48.7 19 PDB header:transferase
Chain: D: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of ornithine carbamoyltransferase from gloeobacter2 violaceus
105c2e77B_
not modelled 46.3 10 PDB header:oxidoreductase
Chain: B: PDB Molecule:lactate oxidase;
PDBTitle: crystal structure of l-lactate oxidase with pyruvate complex
106d1tb3a1
not modelled 43.3 14 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
107d1p4ca_
not modelled 41.9 18 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
108c1zmrA_
not modelled 41.6 17 PDB header:transferase
Chain: A: PDB Molecule:phosphoglycerate kinase;
PDBTitle: crystal structure of the e. coli phosphoglycerate kinase
109c1xuzA_
not modelled 40.8 16 PDB header:biosynthetic protein
Chain: A: PDB Molecule:polysialic acid capsule biosynthesis protein siac;
PDBTitle: crystal structure analysis of sialic acid synthase (neub)from2 neisseria meningitidis, bound to mn2+, phosphoenolpyruvate, and n-3 acetyl mannosaminitol
110c2p10D_
not modelled 40.7 18 PDB header:hydrolase
Chain: D: PDB Molecule:mll9387 protein;
PDBTitle: crystal structure of a putative phosphonopyruvate hydrolase (mll9387)2 from mesorhizobium loti maff303099 at 2.15 a resolution
111c3q98A_
not modelled 40.6 12 PDB header:transferase
Chain: A: PDB Molecule:transcarbamylase;
PDBTitle: structure of ygew encoded protein from e. coli
112d3clsc1
not modelled 38.5 15 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:ETFP subunits
113d1efvb_
not modelled 38.1 13 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:ETFP subunits
114c3ih5A_
not modelled 37.2 16 PDB header:electron transport
Chain: A: PDB Molecule:electron transfer flavoprotein alpha-subunit;
PDBTitle: crystal structure of electron transfer flavoprotein alpha-2 subunit from bacteroides thetaiotaomicron
115d1t57a_
not modelled 36.2 25 Fold:Pyruvate kinase C-terminal domain-like
Superfamily:PK C-terminal domain-like
Family:MTH1675-like
116c3lxmC_
not modelled 35.6 20 PDB header:transferase
Chain: C: PDB Molecule:aspartate carbamoyltransferase;
PDBTitle: 2.00 angstrom resolution crystal structure of a catalytic2 subunit of an aspartate carbamoyltransferase (pyrb) from3 yersinia pestis co92
117d1djqa1
not modelled 34.6 16 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
118c2a7nA_
not modelled 33.9 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:l(+)-mandelate dehydrogenase;
PDBTitle: crystal structure of the g81a mutant of the active chimera of (s)-2 mandelate dehydrogenase
119c3tpfF_
not modelled 33.7 20 PDB header:transferase
Chain: F: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of anabolic ornithine carbamoyltransferase from2 campylobacter jejuni subsp. jejuni nctc 11168
120d16pka_
not modelled 32.7 17 Fold:Phosphoglycerate kinase
Superfamily:Phosphoglycerate kinase
Family:Phosphoglycerate kinase

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0