Reference sequence (query): batch____ Identities normalised by aligned length. Colored by: property
HSP processing: ranked Search cycle: 3
1 [ . . . . : . . . . 1 . . . . : . . . . 2 . . . . : . . . . 3 . . . . : . . . . 4 . . . . : . . . . 5 . . ] 529
batch____ bits E-value N 100.0% 1:529 MQQRRPVRRALLSVSDKAGIVEFAQALSARGVELLSTGGTARLLAEKGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDAIMEEHQIQPIDMVVVNLYPFAQTVAREGCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEMDDNEGSLTLATRFDLAIKAFEHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNLNFIKKLDMRYGENSHQQAAFYIEENVKEASVATATQVQGKALSYNNIADTDAALECVKEFAEPACVIVKHANPCGVAIGNSILDAYDRAYKTDPTSAFGGIIAFNRELDAETAQAIISRQFVEVIIAPSASEEALKITAAKQNVRVLTCGQWGERVPGLDFKRVNGGLLVQDRDLGMVGAEELRVVTKRQPSEQELRDALFCWKVAKFVKSNAIVYAKNNMTIGIGAGQMSRVYSAKIAGIKAADEGLEVKGSSMASDAFFPFRDGIDAAAAAGVTCVIQPGGSIRDDEVIAAADEHGIAMLFTDMRHFRH
1 UniRef50_B4EYT2 IMP cyclohydrolase n=36 Tax... 790 0.0 1 82.2% 1:529 1:529 MQHLRPIRRALLSVSDKAGILEFAKALVERNVELLSTGGTARLLAEAGLPVIEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDTIMEEHDIRPIDMVVVNLYPFAKTVAHPDCSLADAVENIDIGGPTMVRSAAKNHKDVTIVVNSNDYEKVIEEMDNHQNSLTLDTRFDLAIKAFEHTAAYDSMIANYFGQKVAPYYGDTSQPSGTFPRTLNLNYIKKQDMRYGENAHQQAAFYIEENIEEASIATANQLQGKALSYNNIADTDAALECVKSFSEPACVIVKHANPCGVAIADTLTQAYDNAFKTDPTSAFGGIIAFNRSLDAKTASAVIERQFVEVIIAPSINEDALPILATKPNVRVLACGEWQEAKPALDFKRVNGGLLVQDRDLGMVKEENLRVVTQRQPSEREWKDALFCWKVAKFVKSNAIVYAKNDMTIGIGAGQMSRVYSAKIAGIKAADEGLEVAGCAMASDAFFPFRDGIDAAAMAGVTCVIQPGGSIRDDEVIAAANEHNIAMIFTNMRHFRH
2 UniRef50_B0UWT1 IMP cyclohydrolase n=50 Tax... 785 0.0 1 76.0% 1:529 1:532 MQLNHPIRQALLSVSDKSGIVEFAQGLVRRGVKLLSTGGTAKLLAENGIPVTEVSDYTGFPEMMEGRVKTLHPKIHGGILGRRGIDDEVMMQHQIDAIDMVVVNLYPFAATVAKPDCTLEDAVENIDIGGPTMVRSAAKNHQHVAIVVNNSDFNAILAEMDQNRNSLTLETRFDLAIKAFEHTAQYDSMIANYFGQMVKPYFRAEEEAEAkfPRTLNLNFIRKQSMRYGENGHQKAAFYVEQDVKEASVSTAKQLQGKALSYNNIADTDAALECVKSFSEPACVIVKHANPCGVALGKDILEAYNRAYQTDPTSAFGGIIAFNRELDEDTAKAIIERQFVEVIIAPTVSSAAQEIVKSKKNVRLLMCGNWESAIQRLDFKRVNGGLLVQEADLSMVDLADLEVVSKRQPTKQELEDLLFCWKVAKFVKSNAIVYAKNNQTVGIGAGQMSRVYSAKIAGIKAKDEGLEVKGCVMASDAFFPFRDGIDAAAKVGIECVIHPGGSMRDQEVIDAANEHNMVMVLTKMRHFRH
3 UniRef50_Q3IIC3 IMP cyclohydrolase n=114 Ta... 750 0.0 1 75.8% 1:529 1:528 MDTHRPIRRALLSVSDKTGIVEFARALEAQGVDILSTGGTCKLLADNGIKVTEVSDHTGHPEIMDGRVKTLHPKIHGGILARRGQDESVMAENNISAIDIVVVNLYPFANTVAQENCSLEDAIENIDIGGPTMVRAAAKNHKDVTIVVNASDYDRVISEMQSNKGSTTYKTRFDLAIAAYEHTAQYDGMIANYFGKMVPDY-TEEAAEDTKFPRTINMQFTKKQDMRYGENSHQDAAFYVENDIVEASVATATQLQGKALSFNNIADTDAALECVKEFDVPACVIVKHANPCGVSIGSNILEAYERAFKTDPTSAFGGIIAFNQELDAATAEAIVERQFVEVIIAPSVSDAAAKIVSAKQNVRLLVCGQWTDKAAGQDIKRVNGGILVQDRDLGMVTQGDLKVVSKRQPTEQELKDLLFCWKVAKFVKSNAIVYARDGMTIGVGAGQMSRVYSAKIAGIKAADENLEVKGSVMASDAFFPFRDGIDAAAAAGITAVIQPGGSMRDAEVIAAADEAGMAMVLTGMRHFRH
4 UniRef50_Q3JC90 IMP cyclohydrolase n=107 Ta... 737 0.0 1 60.0% 5:529 2:522 ----KPIARALISVSDKTGIVPFAHRLQARGVKILSTGGSAQLLQKNNIGATEISTYTGFPEMMGGRIKTLHPKIHGGILGRRETDATTMAEYNIAPIDLVAVNLYPFEQTVAKPDCDLATAIENIDIGGPTLLRAAAKNHAAVTVIVDPDDYERVLREMEANGGALSSSTRFELAVKSFEHTARYDATIANYLGALTPNGE------KSAFPRSYNIQFAKKQEMRYGENPHQRAAFYVEQPPPAGTIATAQQLQGKTLSFNNIADTDAALACVKAFRepTCVIVKHANPCGVATGINLQEAYERAYAADPVSAFGGIIAFNEPLDPTTAKTIIKRQFAEVIIAPAVTTTAQEILTSKPNIRVLACGEWSSQtaGWDYKRIVGGLLLQDQDTDTVPLEALQTVTERSPTPQELKDLLFAWQVVKFVKSNAIVYAKNGRTIGVGAGQTSRVMSSQIAELKAKEAGFSTQNAVLASDAFFPFRDGLEAAAKAGICAVIQPGGSRRDKEVIAAANEWDMAMLFTGMRHFRH
5 UniRef50_B7V1R6 IMP cyclohydrolase n=154 Ta... 733 0.0 1 68.6% 2:529 5:535 -TTRLPIRRALISVSDKTGVVDFARELVALGVEILSTGGTYKLLRDNGISAVEVADYTGFPEMMDGRVKTLHPKVHGGILGRRDLDGAVMEQHGIKPIDLVAVNLYPFEATVARPDCDLPTAIENIDIGGPTMVRSAAKNHKDVAIVVNAGDYAAVIESLKA--GGLTYAQRFDLALKAFEHTSAYDGMIANYLGTIDQTRDTLGTADRGAFPRTFNSQFVKAQEMRYGENPHQSAAFYVEAKKGEASVSTAIQLQGKELSFNNVADTDAALECVKSFLKPACVIVKHANPCGVAVVPeiRKAYDLAYATDSESAFGGIIAFNRELDGETAKAIVERQFVEVIIAPKISAAAREVVAAKANVRLLECGEWpeRAPGWDFKRVNGGLLVQSRDIGMIKAEDLKIVTRRAPTEQEIHDLIFAWKVAKFVKSNAIVYARNRQTVGVGAGQMSRVNSARIAAIKAEHAGLEVKGAVMASDAFFPFRDGIDNAAKAGITAVIQPGGSMRDNEVIAAADEADIAMVFTGMRHFRH
6 UniRef50_B7J5P7 IMP cyclohydrolase n=12 Tax... 732 0.0 1 55.8% 7:529 7:523 ------ITRALISVSDKRGVVEFARRLQDFGVEILSTGGTAKALMADGVAVQEVGDYTGFPELLEGRLKTLHPKIHGGLLAKRDDSShqMAEYGIPAIDLLCVNLYPFAETIASADCTLEEAMENIDIGGPTMLRAAAKNWEGVTVLVDPDDYAAVLQEMEQSYGGVGASTRFRLATKVFAHTARYDGAIANYLSSLGPDGNR------TTFPQTLSLQFKKAQDLRYGENPHQAAAFYRD--GSGGGLADAHQLQGKELSYNNIGDGDAAVALVMEFAEPACCVVKHGNPCGVAVGPDLLGAYQRAWAGDPISAFGGIVACNRPLDAQTAE-LISDQFIEMVLAPAILPDARPILAKRKNLRVLAFDdrAWRRTGWDYKRVRGGLLVQNFDQAMEAETDWKVVSERAPTVQEARDLAFVWRVGKYVRSNAIVYGREGQTVGIGAGQMSRVDAARCGVAKALELGFDLHGAALASDAFFPFRDGIDAAAAAGVKAIIQPGGSIRDEEVIASANEHGIAMVFTGVRHFRH
7 UniRef50_UPI0000E87EB1 probable phosphoribosylamin... 725 0.0 1 55.8% 5:529 2:516 ----IKIKRALISVSDKRHVLELAKVLTQLNIEILSTGGTAKLIRDEGYAVIEVSEYTKFPEMLNGRVKTLHPIIYGGILAVRDNHEhtMEKHNIPEIDLVVVNLYPFEETIKNPNCTLEEAIENIDIGGPTMVRAAAKNYKSVAILTNPSDYSLLTEQLIKNNGMLEEDLLFTLSKKAFLHTAHYDAAISAYLNNNVT----------EDFPETMIQVMHKSLDMRYGENPHQKAAFYKEQNIKESSLSNFTQIQGKELSFNNLNDSDNAWECVKNFVDPTCVIVKHANPCGVCSSESIDKAYLGAFTTDPTSAFGGIIAFNKSIDAITASSII-KQFVEVIIAPEFSPEALKIFKTKENVRLLRVPI-GSTKDSLDFKKIGGGWLVQSEDSYDININKCEVVSKKKPTEKQLIDMAFAWKIAQYVKSNAIVFCRNSQTIGVGAGQMSRIDSTKIAAIKAQHAGLSIKGSVVASDAFFPFRDGVDELASHGAQCVIQPGGSMRDQEVIDAADEHGLVMLFTKIRHFKH
8 UniRef50_Q3SG45 Phosphoribosylaminoimidazol... 723 0.0 1 64.8% 7:529 3:519 ------IKRALLSVSDKTGLVDFARALATAGVELLSTGGTAKTLRDAGLAVIDVSEYTGFPEMLDGRVKTLHPKVHGGILARRDLDDhtMDTHSLGYIDLVCVNLYPFVATVSKP-HTLDDAIENIDIGGPAMVRSSAKNYRFVAIVTDPADYPALVVEMQANAGALTDATRFTLAKKAFSHTAEYDGAISNYLTSLNDANERE------TFGEKLNLQFTRAQICRYGENPHQAGAFYVESDAPAGTIATARQIQGKELSYNNIADTDAALECIKQFDapACVIVKHANPCGVAYGTSLMEAYDRAYATDPESAFGGIIAFNGRLDGATAAAIVERQFVEVIIAPAVSPEASAAVAAKKNVRLLECGQWTGSVAQLDMKRVAGGLLVQDADVLL--NAELKVVTQRAPTDKEMDDLLFAWRVAKFVKSNAIVYAKDRMTIGVGAGQMSRVNSARIAAIKAEHAGLVVPGSVMASDAFFPFRDGIDQAAAAGIKAVIQPGGSMRDDEVIAAANEHGLAMVFTGTRHFRH
9 UniRef50_A3DEU9 IMP cyclohydrolase n=20 Tax... 712 0.0 1 51.6% 7:529 2:514 ------IKRALISVSDKTGIVEMARELQSMGVDIISTGGTAKTLSDAGIKVINISDVTGFPECLDGRVKTLHPKVHAGILAIRSNEEhqLKELNIETIDMVIINLYPFKQTILKENVDLSEAIENIDIGGPTMIRAAAKNYQDVVVIVDPSDYAAVLEELKTTK-DVSLKTKFKLAYKVFEHTSHYDTLIAKYLREQIG---------EDEFPQTLSLTFEKVQDMRYGENPHQKAVFYKEVGANVGCITAAKQLHGKELSYNNINDANGAIEIIKEFDEPTVVAVKHANPCGVASASNIYDAYIKAYEADPVSIFGGIIAANREIDEKTAEEI-NKIFVEIVIAPSFTEGALKILTQKKNIRLLQLEDISAKIPkyDMKKVPGGLLVQNYNSELLNMDDLKVVTEKKPTQEELEDLIFAMKVVKHTKSNGIALAKGKQTIGVGPGQTNRVTACKIAIE---YGGERTKGAVLASDAFFPFADCVEAAAAAGITAIIQPGGSIRDQESIDACNKYGIAMVFTGMRHFKH
10 UniRef50_C5CL84 IMP cyclohydrolase n=10 Tax... 708 0.0 1 58.2% 8:529 3:535 -------QTALISVSDKTGILEFAQALHALGIKLLSTGGTAKLLADAGLPVTEVADHTGFPEMLDGRVKTLHPKIHGGLLARRDLPAHVAaeHGIDTIDLLVVNLYPFEATVAKAGCTLEDAIENIDIGGPAMVRSAAKNWKDVGVLTDASQYAVALAELQA-GGKLSDKTKFAFSVAAFNRIADYDGAISDYLSAIddASIGQASPTRSMFPAQSNGRFVKVQDLRYGENPHQQAAFYRDLHPAPGSLVSAKQLQGKELSYNNIADADAAWECVKSFDVPACVIVKHANPCGVAVGKDAAEAYGKAFKTDPTSAFGGIIAFNRPVDGETAQAI-AKQFVEVLMAPGYTPEALAVFQakQNVRVLEIadWDNGRNLMDVKRVGSGLLMQTADNHELAASDLKVVTKKQPTPEQLQDLLFAWKVAKYVKSNAIVFCAGGMTMGVGAGQMSRLDSARIASIKAEHAGLSLKGTAVASDAFFPFRDGLDVVVDAGASCVIQPGGSMRDQEVIDAADERGVVMVLSGVRHFRH
11 UniRef50_B3QS62 IMP cyclohydrolase n=460 Ta... 696 0.0 1 50.8% 4:529 3:525 ---ERKIKRALISVSDKTGIIDFAKSLAEFGVEIFSTGGTLKKLIEAGIAAKSISEITKFPEIMDGRVKTLHPAIHGGLLAVRGNSDhqAAENNINFIDLVAVNLYPFEATVAKPDVTFADAIENIDIGGPSMLRSAAKNHKSVTVITDAADYQCVLEEMRANDGATTEATRLYLAKKVFALTARYDGAISNYLEKI-------SQTDESVLPNHLSVSLTKEIDMRYGENPHQKAGFykVGEQNLSFDEFFEKLHGKSLSYNNLLDISAAAGLIEEfaEPTVAIFKHTNPCGVAQADSLETAYRKAFSTDTQAPFGGIIAVNRPLDMATAKAI-NEIFTEIVIAPEFEEGVLEYLMKKKDRRLIR-QLKALPSSALEFRSTVCGLLVQDKDAKTATKEELKVVTKRQPTEAELEDLLFAWKICKHVKSNTIVYAKDMQTVGVGAGQMSRVDSSRIARWKAGEVNLELKNSVVASDAFFPFADGLIAAAEAGASAVIQPGGSIRDEEVIAAADERNIAMVFTGTRHFRH
12 UniRef50_Q2RN46 IMP cyclohydrolase n=15 Tax... 691 0.0 1 54.6% 1:529 1:526 MLHSLPIRRALISVSDKGGLVPFARFLADHDIEILSTGGSAKALADAGIPVTEVADFTGFPEMLDGRVKTLHPKIHGGILGIRDNPEHqmAAHEILPIDLVVVNLYPFEATVAK-GAAFEDCVENIDIGGPALIRAAAKNHEAVTVVVDPEDYQPVMDAMTAEGGATTLELRRKLASAAFARCGAYDGAISRWFQGQVGDET----------PRHIVFAGRLRQTLRYGENPHQKAAFYG-HGIARPGVASAEQLQGKELSYNNINDTDAAFDLVCEFAEPAVAIIKHANPCGVAQGASVVEAYKAALACDPVSAFGGIVALNRPIDRDSAVEI-TKIFTEVVIAPDADAEARAIFAAKKNLRLLLTGVVADTtpGLTVRSVAGGMLVQDRDAADLLSADLKVVSKRTPTERELADMLIAFKVCKHVKSNAIVYVKDGATVGIGAGQMSRVDSARIASWKADEAAEAaqGSVVASDAFFPFADGLLAAAKAGATAVIQPGGSMRDDEVIKAADEAGLAMVFTGLRHFRH
13 UniRef50_B0SGW3 IMP cyclohydrolase n=8 Tax=... 682 0.0 1 49.0% 5:529 2:513 ----IQIKRALVSVSDKTGITEICSFLTKHGVEILSTGGTYDALSKAGIAVKKVDEFTGFPEILHGRVKTLHPKIHGGLLGDTTNPDhqMESNGIVPITLVIVNLYPFVKTVMKPDVTLEDAIENIDIGGPSMLRSAAKNHKNVVVLTDPKDYESFQNEFTTNNGKISRETAFGYAAKVFSETASYDSAISSYFNKRLGI----------KYPDKITFAFNKKQKLRYGENPHQDAAFYEPLFLK----SQFEALQGKELSFNNMLDFDAAFHVASLLPKNAVSIVKHLNPCGIAFGETVLESFELARKTDPISAFGGIIGIHGRVEKESAEEI-TKNFVEGVIAESFSNEALEIFAKKPNIRLIPIAKFDEALDELDLRSLHHGLLIQNRDYDLITKDKLKIVSKKQPTEDDLEGLMFAWNCVKFIKSNAIVYTDQNSTLGIGAGQMSRVDSVELGAMKAQKVGLSVVGSYVGSDAFFPFRDGIDAIAKVGAKAIIQPGGSIRDEEVIQAADEHGLIMVFTGMRHFRH
14 UniRef50_B2KCF7 IMP cyclohydrolase n=1 Tax=... 679 0.0 1 46.3% 1:529 1:517 MTQERKIKRALISVSDKTGLEVFAKGLHKLGVELVSTSGTAKFLKAAGLPVRDLSDLTGFPEILDGRVKTLHPRVHGAILYKRDDDAhvIKDMGIEDIDMLVVNLYPFRETAAKAKHSFdeVIENIDIGGPSMLRSAAKNFAHVAVLCRPKDYEVVLSEMAASQGALSYATRQRLCVEAFTHTAEYDAAISEEF----------KKGLNHEFPESKIVVLHKTQDLRYGENPHQKAVLYSQKKDFS-----FEQLHGKELSYNNILDAFGTWDAVCDFDLPACVIFKHVTPCGIGTGKVLTEAFNNAWACDPKSAFGGIIALNKPMQRDIAEAI-SKVFIEAVCAPDYDLESLEILKQKKNIRILKRNSPLS--AAYQLKSVGDEVLLQQPDRTLLLDNKWDCVTKRKPTEEEDKALKFAWASVKHVKSNAVILTSESASVGIGAGQMSRVDSVKMAGMKFEeeNKKPKVLVIGSDAFFPFRDGVDAAAKLGVSAIVQPGGSVRDEEAIAAADEHGIAMIFTGLRHFRH
15 UniRef50_D1I1D8 Whole genome shotgun sequen... 676 0.0 1 46.0% 2:529 76:604 -SNASGNKQALISLSDKKDLAFLGNGLQSLGYTIVSTGGTASALENAGVSVTKVEQLTCFPEMLDGRVKTLHPNIHGGILARRDQKLhaLNEHGIGTFDVVVVNLYPFYDKVSSGGIEFEDGIENIDIGGPAMIRAAAKNHKDVLVVVDSQDYSALLEFLQGNQD--DQLFRRKLAWKAFQHVASYDSAVSEWLWKQ---------TVGDKFPPSLTVPLSLKSSLRYGENPHQKAAFYVDKSLSegGIATAIQHHGKEMSYNNYLDADAAWNCVSEFKNPTCVIVKHTNPCGVASRDDILEAYRLAVKADPVSAFGGIVAFNIEVDEALAKEIrtRMFYEIVVAPKYSQKGLDILRGkkTLRILEAG--KNEKGKLSLRQVGGGWLAQDSDDLTPEDIPFKLVSEKAPPESELRDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRRESLRIAVRKA---GDEVKGAALASDAFFPFadAVEEACESGIGIIAEPGGSIRDGDAIDCCNKYGVSLLFTNVRHFRH
16 UniRef50_Q03Y85 IMP cyclohydrolase n=69 Tax... 671 0.0 1 46.3% 7:529 1:508 ------MTRALLSVSDKSGLIPFAKNLVELGYELVSTGGTHKVLIDAGLDVISIDEVTDFPEMLDGRVKTLHPRVHAGLLARRDLPEhkLAEFDITPIDMVVVNLYPFKSTIQKEGVTEAEAIENIDIGGPSMLRSAAKNFASVLPIVDPKDYDVVVNKLKA--GEVDREYRKSLAAKVFQHTASYDALIANYL-------------TETSFPENLTLAYEKFDDMRYGENPHQPAAAYKTALPEAYSVLNADILHGKQLSYNNIRDADAALRIIAEYEETTVVTVKHMNPAGIGQGQTLEAAWDQAFAADDISIFGGIVALNREVDAATAEK-MHDIFLEIIIAPSFTPEAYEILAAKKNLRLLTLPFTTSIPQKLEVTSVLGGVVVQERDLVGESENNFTVVSKAQPTKEQLQAMVFAQKVVKHVKSNAIVVARNGQTLGIGAGQPNRIDSVVYSIQKAEKKP-GFDEAVLASDAFFPMDDSVQYAAEHGIKAIVEPGGSIKDKDSIAKADELGVVLIFSGTRHFKH
17 UniRef50_B4U6L4 Phosphoribosylaminoimidazol... 668 0.0 1 47.0% 9:529 2:506 --------RALISVYDKTGILELAKELLNQGYEILSSGGTYTYLKNAGVDAIEVSEVTGFREILGGRVKTLHPAIHGGILFREDVEkeEIKENSIEPIDIVVVNLYPFEKKM-KELKDIDALVEFIDIGGPTLVRAAAKNHKRVSVLTDIEDYGWFIEKLKMN--AVSQQDRKYLALKAFWLTSYYDAVIASYFSKVFGFSEKDFKHH--------TVPMFLRDELRYGENPHQQAYLYENP-LEENGIVRADVLQGKKMSYNNYLDADSVVKLMSEFSNPCCAIVKHNNPSGITTDNNILEAYKKAFQCDPEAAFGGIVAFNKVVDKDVAKAI-TEHFYEIVIAPEFTEEAVEEFSKKKNLRLVRY---KNYNQNIDLRSISGGFLVQDIDDKLY--ESIEIVSLRRPTEQELEDAIFAWKVAKWTKSNAIVIAKNNQTIGIGAGQVSRVDSLRSAIRKAKNFSHDLKGAVVASDAFFPFRDSIDIAAEEGISGTIQPGGSIRDKEVIEAVNEHNMFMIFTHMRHFRH
18 UniRef50_B3DV28 AICAR transformylase/IMP cy... 667 0.0 1 44.7% 7:529 1:510 ------MSAAFLSVYDKTGIVEVARVLSQAGIDIISTGGTARLLKNAHIPVQEVSDVTGFPELLEGRVKTLHAKIHAGILYKREKPDheITELGIPQIQYVIVNFYPFVDAVKK-NLPIEEMLEYIDIGGCTLARSAAKNYPHVTVVVDPADYTELISQIQT-MGSTSSSLRKKLAFKAFNLTSYYDSQIARFFQEKLHMR---------FFPPESSIPLYGYSPLRYGENPHQHAALY------GDFWNYFQQLQGKDLSYNNILDIDAAVRILSEfdSAIAAIFKHSSPCGVGMGMTVKEAFEKAFKTDKESPFGGVIALNKPLDPALAE-ILADIFVEVIVSPEYEPESLQLLQKKKNLRLIQVSLNKLPPPRYIIRSLCgsYLLQEPDNMLLDQEKMKIVSLRKPTPEEMNKCLFGWKVVKHVRSNAIVFSDADRTLGIGAGQPSRVDAVRIAIDKAGREGLSLKGSAVASDAFFPFPDGLELAASAGATVVIQPGGSVRDKEVIEAANKHNMAMIFTHLRHFLH
19 UniRef50_Q28K03 IMP cyclohydrolase n=22 Tax... 665 0.0 1 56.0% 1:529 1:532 MTDPAPLTRALLSVSDKTGLIEFATDLSSRGVELLSTGGTAKALREAGLDVRDVSEVTGFPEMMDGRVKTLHPMIHGGLLALRDNDAhaMKEHGIGAIDLLVVNLYPFEATVA-AGADYDTCIENIDIGGPAMIRAAAKNHGAVTVLTDSSQYAGLLSELDAngGGTSFQFRQRMAQAAYGRTAAYDAAVSSWMAG----------AAEIKTPPHRAFAGSLAQEMRYGENPHQKAAFYLD-GSSRPGVATAQQHQGKALSYNNINDTDAAFELVSEfdGPAVAIIKHANPSGVARGNSLAEAYKAAFDCDRTSAFGGIVALNQTLDAATAEEIV-QIFTEVVIAPDADEDAKAIFAAKKNLRLLTTGGLPdrAPMVAYKQVAGGLLVQDKDTGHVDPELLEVVTKRAPSAQELADLRFAWTVAKHTKSNAIIYAKGGATVGIGAGQMSRVDSSTIAALKAARMGTeaKGSVVASDAFFPFADGLLAAAEAGATAVIQPGGSMRDADVIAAADEAGLAMVFTGMRHFRH
20 UniRef50_UPI0001C16867 Bifunctional purine biosynt... 663 0.0 1 45.6% 8:529 3:516 -------RLALISVSNKIGIIDLARTLVefQFDIVSSGGTAKTLKEAGIPVTKVSDYTGSPEILGGRVKTLHPRVHGGILARRDIPqmDLENNQIHPIDLVVVNLYPFEETIAHSDTTLTQAVEQIDIGGPAMLRAASKNFAHVTVLCNPEQYGSYLQQLREN-GSVSWEFRQKCALQGFLHTASYDHAIATYLSQRE-----DPSLSKNDLTENYNISGKRIQTLRYGENPHQPATWYG-TGSNPTGWTTAIKLQGKELSYNNLVDLEAARQIIAEFTdpAATIIKHNNPCGTAEADTIFTAYQNAYNADSVSAFGGIVALNRPIDTLTALE-LTKTFLECVVAPDCDQEAQEILNKKGNVRVLILPDLGSG-PKETVKAIAGGLLVQTADDTISDSAKWQVITKVKPTPEELVELLFAWKVCKHVKSNAIVISKQRTTLGVGAGQMNRVGSTKIALEQA---GARTKGAVLASDGFFPFDDTVRTAAAAGITAIVQPGGSLRDQDSIKAADELGLSMVMTGVRHFLH
21 UniRef50_C7MMK7 Phosphoribosylaminoimidazol... 661 0.0 1 48.0% 3:529 2:566 --ESPQIRRVLISVTDKTGVIDFARALseFGAQIISTGGTARTLSEAGVPVTSIEDVTGFPEMMDGRVKTLHPSVHGGLLARRDNPQhdAAHQGIEMIDMVVVNLYAFEKTV-TQGADFAECIEHIDIGGPSMLRSAAKNFESVTVVTNPFSYKHILAEMRETGGTTTRATRFVLAREAFRLTGAYDTAITDWLTNQMPENVDSSKfyEEEWPQQLNLSYSRVQILRYGENPHQAAAFYRLPDAPSHSLAHAEQLGGKPLSYNNLLDADACWTIVCGLNETAVVILKHQNPCGSACADTVGEAFERAFACDEKSAYGGIIAANRMVTADmaRINAHKLFMEVLIAPDYEPAALELLQQKKNLRILRtgTDVFDATRQELRSIDGGLLVQTIDTVSEDPATFTIPTKRKPTAAELDDLLFAWKVCKGVKSNAILVAKNKAGIGMGPGQPNRVDSARIACQRA---GVACKGAVAASDAFFPFRDGVDTLAEQGITAIIQPGGSIHDDEAIQAADEAGITMVFTGHRHFRH
22 UniRef50_Q86L14 IMP cyclohydrolase n=1 Tax=... 659 0.0 1 46.4% 9:529 2:542 --------QALLSVYNKSGIVEFSKILSSKGFNLISTGGTAKSLVDNGLKVQQVSDVTEYPEMLDGRVKTLHPKIHGGLLARPELAHHQAdkYNIKPISIVVVNLYPFVETVSKESTTLEEAIENIDIGGHTLIRASSKNFQNVLIIVDPSDYKWIGERIQSStsSITLEERKKLALKAFQHGCSYDAAVSQYLSKVELTNAtdSASVNVEFPQTFLPLYEKKNDLRYGENPHQKAALYQCPG--TGGIANAQLLHGPALSYNNILDGDAALKAVREFDRCACVVIKHTNPCGLSVGVnqAEVYKRAFNGDPKSAYGGILGFNRTLTLETATA-LKSVFYEVIIAPDYTEDALALLSKKEKLRILRIPEAANQIQFtdIRTITGGALLQSPndLAEATKNWKVVTENKPTEQQMKDLLFAWRVSKHVKSNAIVLSKDETIVAIGAGQPNRSQSVDICM---KVGGDKVKGSVLASDAFFPFADSIDLAHQGNIACIVQPGGSIRDQEVIDAANKYGIPMVFTGNRNFLH
23 UniRef50_B2A5W1 IMP cyclohydrolase n=3 Tax=... 658 0.0 1 43.1% 6:529 5:509 -----KINRVLLSVYDKTGLITLAQELKDMGVELVSTGGTLRHLQTHGIPVYSVEEVTGFPEILSGRVKTLHPKIHGGILA-KNRENEELSSLDIKTFDLVIVNLYPFEQVMQKAEATEEEVMENIDIGGPTMIRAAAKNWYRVGVCVDPTDYEVLTQQLKQYHG-LTDEFRKTLARKAFKHTAQYDKAIFNYFESVDTNKDDETEL---KFPEF---NLLESRELPYGENPHQKASLLMESQK-------FIQHQGKGLSYNNFQDIDAAIKLVHEFQKPAVVAVKHTNPCGVGVSNTIEEAYDKAYQGDPVSIFGGIVACNRPVTEELASK-LTEIFLDVIIAPEFEPRALEKLKSKSGTKVVEMDLEKMVGNKVEIKSTTFGYLCQEADYHHPHPQNWDRVAGEQAKPEEIDDLIIAEKIVKHVKSNAIVVVKEGQSLGIGAGQMNRVGASRIALENA---GKESQNSVLASDAFFPFNDVVKLCSQYGVSAIVQPGGSKRDQDSIDLAQETGITMYFTGIRHFKH
24 UniRef50_B1H076 Bifunctional purine biosynt... 657 0.0 1 44.6% 7:529 1:518 ------MSTALLSVSDKTGIIDFAKELKNLGWNIISSGGTAKILKENSIECREISEVTEFPEILGGRVKTLNPKIHGGILAIRNKTDhqLKRHGIGTIDIVVVSLYPFEAAINKIPKPaqNVIENIDIGGVALLRAAAKNYKDVIVICDLNDYKVVIKNLKNN--SITEELKLALAAKAFRHTAYYDSLISTYL-------------TYEKFPMQIAIPLRKLSKLRYGENPHQEAALYSniEQDKSVVISAKQLHGKELSYNNYLDLEAAWQLVHEFNNPACAVIKHNNPCGCAESTDIKDAYLKALDCDPVSTFGGIIAFNKAVEKDTAVE-VSKLFVECVIAPDYSKEALDILTQKKNIRLLIQTIpqEEKNSVEYRIMSHGMLAQDRDNQLLN--EIKLMTKRQPTKAESEALDFAWKVSKHVKSNAIILARGTQTVGVGAGQMSRIDSLKIAAEKMKslDERLFPLVLASDAFFPFPDVVEESAKVGVTAIVQPGGSVKDNESIKSADDRNIAMIAAGMRHFRH
25 UniRef50_B2URE6 Phosphoribosylaminoimidazol... 655 0.0 1 47.2% 7:529 3:515 ------IQRALISVSDKTGLEEFAKGLHEFGVELISTGGTAAFLKGLGLPVIEISDYTGEPELFEGRLKTLHPMVHGGLLHRRDNEEhqAKENGIKPIDLVCVNLYPFEETVARPGVTLEEAIEKIDIGGPSMLRSAAKNYASVTVVSDPADYARILDEMQTHKGDTTLKTRENLAVKVFMRTSNYDNAITNYLGHQ------SAESTKGSFC----ICAPLYQELRYGDNPHQEASLY------GSFGDIFHQLQGKELSYTNVLDIEGAAELITQFRRPTVGILKHTNPCGVGQDddLRNAWQKAFETDTQAPFGGVIVVNRPMTEGLAR-VLSAIFTDVIIAPEYDAEARAILQKKKNCRIIRMNTEAWMKARReiRSAPGGFMTMKRDTDVMGLDNlkVVTKRPPTEEELTAMRFNWRVVKQVHSNAIVFGGTDRTLGIGAGQMSRVDSARIAVWKAGQAGLDLKGSVVASDAMFPFADGLQVAIDAGATACIQPGGSIRDEEVIAAADAAGIAMVFTGHRHFLH
26 UniRef50_C0QXU6 IMP cyclohydrolase n=7 Tax=... 654 0.0 1 44.6% 7:529 2:509 ------IKRALISVFYKDGILDFAKFLTSKNVEIVSTGGTYKYLKENNIPVIEVSEVTGAKEMLDGRVKTLDPKIHGAILAIRDNPThtIKERGITPIDMVIVNLYPFFEKVQDDNLKFEEKIEFIDIGGPTMLRSAAKSFKDVVVISDVKDYDLVKSEME--KGEVSFETKKYLASKVFNLTSAYDAAVSEFMFNSL-------ESKEDKKLNYLNMSYALQEELRYGENPHQGASYY-VSTTDKGSMKDFEQLNGKELSFNNIRDMDIALKIVLEFDEsaCSAIKHSTPCGAALGSSVLEAYNRTYECDPTSIFGGIVAFNSTVDEATAKELI-KIFLEIVIAKDFTPEALEVLKTKKNLRVIKYKTNTN--DKINLVKVDGGLLVQDEDTTLI--EDYKVVTEKKPTEEEMKNLIFGIKVVKYAKSNAIVVIKDFMAKGIGSGQTNRIWACEDALERAGD------GVVMASDAFFPFRDVVDACAKYNIKAIIQPGGSMRDQESIDACNEHGIAMIFTGIRHFKH
27 UniRef50_A5E8X1 Phosphoribosylaminoimidazol... 650 0.0 1 58.1% 2:529 3:530 -NQLRPVHRALLSVSDKTGLVEFARSLAARGIELISTGGTAKAIADAGLKVKDVSDLTGFPEMMDGRVKTLHPKVHGGLLAIRGNDEHamKTHGIAPIDLLVVNLYPFEATVER-SAPFSDCIENIDIGGPAMIRAASKNHEDVAVVVDVNDYDAVLEDLARHEGSTTLLLRRRLAAKAYARTAAYDAAISNWFAATIQNDA----------PDYRAFGGRLIQSLRYGENPHQHAAFYALPG-RRPGVATARQVQGKELSYNNINDTDAAYECIAEFDPaaCVIVKHANPCGVAEGPDLITAYQKALACDSTSAFGGIIAMNRKLDAATARAI-TGIFTEVIIAPDATEEAIAVIAARKTLRLLLAGALPdrEAGLTAKTVAGGLLVQSRDNAVVDDMTLKVVTKRAPTEAELRDLRFAFRVAKHVKSNTIIYAKDSATVGIGAGQMSRVDSARIAARKALDAASElkGSVVASDAFFPFADGMLACIEAGATAVIQPGGSVRDDEVIKAADEHGIAMVLTGVRHFRH
28 UniRef50_B9EAZ2 IMP cyclohydrolase n=1 Tax=... 649 0.0 1 47.6% 7:529 1:492 ------MRKALLSVSDKTGIIPFAERLTELDFELYSTGGTKKALEDNDIAVKSVSELTNFPEIMDGRVKTLHPNIHGGILADRNNPEhaMETHGIQPLDLVVVNLYPFEATVANPDVTEMDAIENIDIGGPTMLRSSAKNFRHVITVVDPADYDEVIEKLKTD--TLDETFRKQLMIKVFTHTNKYDAAIVNFFSDNTST-------------------------LRYGENPHQKARFIK-TDAKPNTLAGARVLHGKPLSFNNIKDADATLFLVKQFDMPAAVAVKHMNPCGVGTGEVISEAFQNAYDADSQSIFGGIVALNREVDKATAEK-MHAIFLEVIIAPKFSDEALEILTAKKNIRLLEIDMDMDK-DEEEFVSVSGGYLVQDKDLLNVTREDMRVVTNTEPTEAQWKAIELGWKVVKSVKSNAIVLANDKQTVGIGAGQMNRVGAAKIAIERAIEMN---DNVVLASDGFFPMSDTVETAYAAGIKCIVQPGGSIKDQDSIDKANEYGIAMVMTDVRHFKH
29 UniRef50_Q5GSM5 AICAR transformylase/IMP cy... 649 0.0 1 45.4% 4:529 11:517 ---KVKIKRALISVYDKTNIIDLASFLIQQQVEILSTGNTYKVLSDAGIKTQEVSNYTQFPEILGGRVKTLHPKIHAGILFDREKHKKEMQDLGIEPIDLLVINLYPFWETVS-SGSSEEQIVEQIDIGGVALIRAAAKIFHFTSVISSVQDYEALKAEMMKNNNKTTLEYRKYLATKAFALTAHYDSNIYSWF---------LSKSKSSELPEFFVLYGSKVQELRYGENPHQKAAFYSN----QFTKYPLEKIHGKELSYNNIVDIESALNIVSEFKEPVAVIIKHNNPCGAAVGNSVLEAYKKALSCDEISSFGGIVALNREIDLKLAEK-LSEIFLEVVVAPSVSDEALKTLQRKKNLRVIIYRSLQQ-NAKYQIKNIIGGFLVQENNSYAIKAEEMSQVTEHTATEEEKEDLIFAWKICKHVKSNAIVIAKGGCAIGIGAGQTSRIDSVNIAVKNADE---KCKGAVLASDAFFPFPDSIVESAKHGITAIVQPGGSLKDQDVIKAANENEIAMFFTGIRSFFH
30 UniRef50_A7I7L2 Phosphoribosylaminoimidazol... 647 0.0 1 48.9% 7:529 31:525 ------MKWALLSVWDKTGIVDLAQALIQHNFSIMSSGGTGTALAGAGIPFTEVSRYTGFPEMMDGRVKTLHPKVHGGLLGRRQIDDAIMAKYGINRIGLLVVNLYPF-ERMSRESLPLEKLIEYIDVGGPAMIRAAAKNFKDVAVVVDPSDYPEVVKTLSSNVG-FSHEQRLIFAKKAFARTAAYDAAISNHLSN-----------LDNTFPPILTLQFTNGRMLRYGENPHQQAAVYGTT-----GIAGAEPLQGKQMSYNNYLDVNAGTALLAEFEEPTAVIVKHNNPCGVSVGTDILEAYLSARDVDPVSAYGSVVSLNREVDKKLAEAIDS-TFVEVVAAPSFTRDAVEAMRKKENMRVLIL---PERNTSDEVRTIDGGVLVQ---RTPAYQENWQVITDRDPTTDEMSALRIAWKVCKHTKSNTIIFADQKRTLGIGAGQMSRVDSAKIAIEKAC---APLAGSAVASDAFLPFPDTLEVAAKAGATALVQPGGSIRDDEVIKAANRLNVAMVFTGVRYFRH
31 UniRef50_Q89B23 IMP cyclohydrolase n=1 Tax=... 646 0.0 1 41.4% 1:529 1:529 MTNRNVIKNVLISVSDTSNIIEFSKSLISKNIKLFATKGTANFLKKNNIYATDITNYTNFPEIMNGRIKTLHHKIYASILAQPKHDKKTIEKYNIILMDIVVINFYPFEEASNNTNLHLNDIIEHIDIGGPAIVRAAAKNYKNVLVVTQPNLYQSIVNEMNLNNNIISETTKLKFATIAFKHTMNYDNNIYQYLSKK-NKTVPKNTQLQTLLPSHLTINFKKKQDLCYGENKQQQASWYTNTSKNTSGRMKIKQLQGKILSYNNLSDIHLALSCIHEFNKTTCAIIKHGNPCGVATAKNNDQAYKLAYETDPISAFGGIIVFNQKLNDVTARKIIKTQFSEIILAPDFTQEAKKIFDKKPNLRIIKYDPNYNYLnnIDIKSIYGDILVQSNTNSIININQWDIVSKKRPNEQEINDAKFALRVVKHLKSNSIVLIKNQITISIGSGQTSRIDATKIAIYKANNNNISLNHTTLASDAFFPFSDSIDLISKSGITCIVQPGGSIRDNEIIMSANKYNISMIFTKQRYFKH
32 UniRef50_B0VJP0 Bifunctional purine biosynt... 643 0.0 1 40.0% 8:529 3:515 -------KYALISVADKTGIETLAMELERMGFTILSTSHTADYLKQFCQKVVLVSDLTGFPEILEGRVKTLHPVIYAGILADRNNPAhtLSELKIEHIDVIAVNLYPFASVCWKENATEQEIIENIDIGGPALIRAGAKNYKSVTVLVDPVDYANALELLKQNS-ILPEKFSSYLAQKAFAKTRDYDAEIAAYFASQ-----GIEESITNELPAQLEFAISLKRKLRYGENPHQNGGFYAKVT------SGWELIHGKELSFNNIMDIDSAFRAIRLFGKPTAIIIKHCNPCGIGSDETLAEAYRKAYETDTEAPFGGIVIVNRPLDLETA-TLINNIFTEIIIAPAFEPGVLEFLKKKKNRRLIRysLLEKPLNPIEIKTLTSGYLAQDWDLVNESTENWKIVTNKQPAPEELEALIYAWKAVSVLKSNAIAIAKKDSVLGLGCGQTSRIDAVQLALWKAKKFGHDLTDSVCASDGFFPFRDCIDTLAKNGISAIIQPGGSKNDAECISACNELNIAMVFTGFRHFKH
33 UniRef50_D2R0A8 Phosphoribosylaminoimidazol... 639 0.0 1 46.9% 6:529 5:523 -----PVRRAIISVSDKTGLASFAKGLVACGVEIYSTGGTRKHLIDHGVAARDVAEYTQFPEMLDGRVKTLHPKIFGGILVRHDQPeeLIAEHGIVTMELVVVNLYPFQETIAREGVTREEAIEQIDIGGPSLVRAAAKNHAFTSIVTSAEQYGEVLGEIRAH-GATSLELRRKLAGRAFAKTADYDTAIAAYFAKQ--------EGDDSIFPKQLALTFDRQTELRYGENSHQRGAVYQTRGSSGPSLVTAKQLNGKELSYNNLLDLDSALAIVRGIEMPAVTVIKHNNPCGAATGDSISLACSKALAGDPQSAFGGVLGFNRVLDIATAELLStgLFIEAIVAPDFHPAAVEILRtkANVRLLSVGPLDRPPTAISYRQIEGGMLVQEADVGRDLPSDWKVVTTTTPPPEVTRDLAFGWEMVRHVKSNAIVVVKDTMLLGCGAGQMSRVDSVEISLTKA---GERSTGAVLASDAFFPFADSIERAAKAGIIAIIQPGGSVRDEEVIAACNQHNIAMIFTGRRHFKH
34 UniRef50_B5YDF4 Bifunctional purine biosynt... 638 0.0 1 43.2% 7:529 1:498 ------MKYALISVWDKTDLEKLCNKIINKGYTLLATSSTAKYLKEKGFEVKETSELTGFSELIGGRVKTLHPKIFAGILARRDNPkeDLKKENIPLIDIVVCNLYPFQQVIKNKNTTLEEALENIDIGGVSLLRAAAKNFPFVLVVPSPKYYDEVINYLEKEDNG--LEFRRRMAIKAFSITSTYDNAIMNYLAQ--------------TFEDVISLNLTKKLDLRYGENPQQKAGFYTLNDED----LPFIQYQGKELSYNNLLDTDSAWNLIKEFDEPTVAIIKHNNPCGVASDNDSLKAFIKAFESDPVSAYGGIVACNFEIDENVAKEI-TKHFFEVIVAPSYKEEALKVFSQKKNLRVLKYREDIPENP-FEIRSLRRGVLVQSFNDILFD--NYEVKTSAKPTQKDMEELIFALKVVKHVKSNAIVVSKDKQTLGIGAGQMNRVNAVKIALEQA---GEKAKEAYLASDAFFPFPDSIELAAKYGIKAIIQPGGSIRDNEVIEAAEKNNLILVMISSRHFRH
35 UniRef50_Q18CW0 IMP cyclohydrolase n=19 Tax... 637 0.0 1 41.4% 8:529 3:510 -------KRALISVTDKTGVVEFAKELNKLDYEIISTGNTFKTLKENGVNVMQVEDVTNFPEILDGRVKTLNPYIHGGILYKRDKEShtVNEHKIHSIDLVAVNLYDFEGTL-KAGKSHDEIIENIDIGGPSMIRSAAKNYKDVIVVVDIKDYDSIIEKLKTD--TMTLEDRKKLSYKAFSTTGRYDALISSYFAGEVG----------DTYPDILNLTFQKEQTLRYGENPHQNGFLYSQSNAKNP-ILNYEQLGGKELSFNNLNDLHGCLEVMREfeEVVSVAIKHANSCGVGLGKDAFEAYTKCYEADKVSIFGGIVGITSTIDKATAEK-LNEIFLEIVVAYDFEPEALEILKQKKNLRILKLAKIENSLQPYEMKYLDGKLLIQDRNNILAEKS--ENVTKEKPTDAQLKDMEFGMRVVKNMKSNAIAIVKNGQTLALGCGQTSRIWALKNALE--NNKDKDFTGAVLASDAFFPFDDCVTLAHEYGISAVVQPGGSIKDKDSIEACDKYDMVMVFTGIRHFKH
36 UniRef50_A9IZD0 IMP cyclohydrolase n=326 Ta... 637 0.0 1 53.1% 3:529 12:539 --DLHRVRRILLSVSDKTGVVAFAQALHaySVELISTGGTAKTLIAAGLPVKDVSEVTGFPEIMDGRVKTLHPLIHGALLGIREDPShaMEKNSIHGIDLLVVNLYPFEETIQ-SGADGKTILENIDIGGPAMIRAAAKNYAYTGVVTAINDYDSILAELKQHNGCLSLSMRHQLAMRAYAHTAAYDTAIAAWFARDLKIET----------PSWQSFSGHLESVMRYGENPHQQAAFYRNNE-KRFGVATAKLLQGKALSYNNLNDTDAAFELVAEFDpaAVALIKHANPCGVAEGENLKDAYLKALMCDNVSAFGGIVALNQTLDEECAEEIV-KIFTEVIIAPDATMAAREIIAKKKNLRLLITGGIPnrCGGLLAKTLAGGILVQSRDNVVIDDLKLQVVTKRTPTQDEMRDLQFAFRVAKHVKSNAIVYAKNSATVGIGAGQMSRIDSAKisARRAGLTETLTKGSVVASDAFFPFADGLLAAAAAGATAVIQPGGSMRDEEVITAADEQGLAMVFTGIRHFRH
37 UniRef50_D1VVH5 Phosphoribosylaminoimidazol... 636 0.0 1 44.5% 9:529 2:501 --------RALISVYDKENIVEFARELVALDWEIISTGGTFKILKENNIPVKEVEEVTGQREILSGRVKTLHPKIHGGILFRRDndKKTIEEEQIKPIDMIVNNLYPF-ENCLREGKDHETLIENIDIGGPSMIRAAAKNYKDVLIVTEPSDYKSIIEALKENK--IDMTFRETLARKAFSLTAHYDSVICNYFQEK----------ADEKFPKYINKSYTFSNKLRYGENSHQEAAYYQ-----GKIYAPYKKLHGKEISYNNLYDMFAAVKAAREFDDITVVAVKHTNPCGIGSGKSVKEAFIKARDCDDESIFGGIIAINHIVDKEAAE-LLHEIFLEIVVAQGFTSEALEILEKKKNIRLIELKDFNNFELDTSFKEVLNGIIVQDYDDILLDEDKLQIVSKNKPTEKEMEDLKFAFKCVKYTASNSIVIAKDGASLGIGQGQTKRSWAVEEAIERA---GEKIKGAVCASDGFF-FRDTMELLNKAGVRAIIQPGGSVKDKEVIEYADEHEMAIIFTGIRHFRH
38 UniRef50_B9KZE8 Bifunctional purine biosynt... 636 0.0 1 44.3% 9:529 2:504 --------RALLSVADKTGITVFAQRLVDLGWEIFATGGTARELREHGLPVREISELTGFPELLEGRVKTLHPAVHAAILArrSTDLAQLAERGIAPIQLVAVNLYPFDRHV-TPETPEDVALELIDVGGPTLLRAAAKNFPWVLPICDPCDYEPIADRLAQFGItiDHETRRALAAKAFAHLATYDAQIASYLR-------------TEEFPDLLPIPLRKLQTLRYGENPHQRAAVYQILGI-TPQVSRWQVVGDAALSYNNVLDAVAAWQLVQRFSQPAAVIVKHAAPCGVAVAATPHEAFQRAFEADPVSSFGGIVALNRTLDAETALA-VAQHFFDLLIVPDKQPGVETLLVRRKSLRLVIAPPWTD--PGVVFRSVGDAVLIQSADRPLRLPETWQVVTSRQPTETEWHDLAFAWTVVPFVLSNGVVIARHAQTVGIGGGQPNRVDAVRLALWRA---GERARQAVLASDAFFPFPDSVELAAAAGITAIVQPGGSKRDREVVEAAERAGIAMVFTGERHFRH
39 UniRef50_Q12UR7 Bifunctional purine biosynt... 635 0.0 1 44.7% 7:529 2:538 ------VKRALLSVSDKTGIVDFARGLEQLNIEIISTGGTAKMLRDAGIETIDVSEVTGFPEMMGGRVKTLHPKIHGGLLCMRGDPEheAEKESIKLIDLVAVNLYPFEITVSKEGVNLDEAIENIDIGGPTLLRSAAKNYKSVTVVSDPEDYGEILKELRSS-GTVSDTTREKLAVKVFRYTANYDSNIDTYLSKTLLDE------------DVLRMNFTEGTKLRYGENWHQDATFYKDETIVGPALSNAKQLHGKELSYNNYVDADNALQTIKEvrNPAVAIVKHNNPCGLATGNTLCEALEHAWDGDPVSAFGSIICTNTVFDLESAE-FLKGKFVEIILAPGFEHDALEYLEDksNLRLLELPQFNEAFDTetYKYVIGGMLKQTRNIGLY--EKWDCVTETAYPEEKRGLSEFCICACKSTKSNSVTLakDGcmIAMGAGQPNRVDSIrlAATKAKewQSILSEAVMASDAFFPFDDSIIYSDESKIRYILSPGGSIRDDEVIATANRLNISMVFTGMRHFLH
40 UniRef50_D1B2Y6 Phosphoribosylaminoimidazol... 635 1e-180 1 48.4% 9:529 2:510 --------RALISVSDKTGIVEFARDLVELGFEVISTGGTYKLLKEEGISALEISEVTKFPEMFDGRVKTLNPMIHGGILHRRDLPLhtAQEHGILGIDVVCVNLYPFKETIAKTD-DFDEIIENIDIGGPAMVRSAAKNFSDVLIVTDVLDYDGVIDVLKS--GSNTLEFRRSLMIKAFEHTAAYDSMIANYMNQR----------FNGGFGEKQFIVGTKAFDTRYGENPHQKGALYEF---DYFFTNNFKTLKG-EASFNNMTDINGAVKIAASFgaPAVCIIKHANPCGFAIGENLLDSYVKALKCDPVSAYGGVVAINGTLDKALAEKI-NEIFVEVIIAANVDEEALAVFESKKRIKIfeSKYLVLSEDAYDFKHVDGGFVFQQSDVvdEEVTQAKCLTTRQASKQEMSDLEIAYKVASLTKSNCVVYVKDSAMVAIGMGMTSRVDAAKAALRKAEDMGIDVSGAALASEAFFPFRDSIDAAAVAGVKAIIEPGGSIRDDEVIAAANEHGMALYFTGVRHFLH
41 UniRef50_D2QFV1 Phosphoribosylaminoimidazol... 634 1e-180 1 41.2% 1:529 1:517 MSMSLKISSALISVFYKDGLEPLVRLLHEQNVKLYSTGGTQAFIEQLGIPVTAVEDLTGYPSIFGGRVKTLHPAVMGGILYRREMPeaQAERHQIPPIDLVIVDLYPFEETVA-SGASDEDIIEKIDIGGISLIRAAAKNYNDVLIVSSRSQYGDVVNLLTEKNGTTDLADRRQYAGKAFSVTSQYDTAIQAYFA-------GEQAPKADATGTVYDFRTMPASHLRYGENPHQQATFYGDLE------AMFDKLHGKELSYNNLVDVDACVNLIDEFTDsaFAIIKHTNACGIATAPTAKEAYLNALACDPVSAFGGVVITTATVDLETAEE-LNKLFMEILIAPDYTPEALTLLKSKKN-RIL-LKRNAVELLSVMFKTILNGVLEQDKDNQTETASQFTTVTDKTPTDSEVRALEFALKVCKHTKSNTIVLAKEGQLLASGVGQTSRVDALRQAIEKAHSFGFDLNGSVMASDAFFPFPDCVEIAGNAGITAVVQPGGSIRDQDSIDYCNQHALAMVTTGVRHFKH
42 UniRef50_D0RQR1 Phosphoribosylaminoimidazol... 632 1e-180 1 42.5% 5:529 2:518 ----NKITKALISVSDKTNLETVLGVLKKHNIEIISTGGTYKFITDKGFECTEISQYTGTPEILEGRVKTLHPKIHGGLLGDIDKKNHqmKENQISEINLVIVNLYPFENKLLEGDVSFEEMIENIDIGGPSMLRSSSKNFKHVTVLPSPKYYDEFLKEFEQNKGSTSIEFRKKMSAITFSETAYYDSLISNWMSEQNGI----------KFLDKKTIPGKILQKLRYGENPHQESRVFEIVNNKK-GFSNLNQIQGKELSHNNYLDSFNAYSLVNDFDKQscAVIKHNNPCGCASDANGLKAYLNALSGDPTSAFGGVVAFNYSIDESIATEIV-KTFYEVILASKVSNEAKKILSSKKNLRVLEY-ELVEKSPSLSVAFMQKTFLLQDENFSSLTKKDLKIVTKAKPTEIEIDNLLFANQVCKHVKSNAIVITKDNKTLGVGAGQTSRVGSTEIACKNALKFfkEIVGSSAASDAFFPFADGLENLIQAGVKSIIQPGGSIRDQEVIDAADKAGISMVFTGIRNFKH
43 UniRef50_D0JBE9 Phosphoribosylaminoimidazol... 629 1e-179 1 40.5% 7:529 17:527 ------MKRALISVYEkeKLFNFASFLDQKGYQIISTGGTYQYLIKNGlnVIEISDVTDFPEILDGRVKTIHPNIYGGILANRSIEKHIQSihNIHLIDIVLVNFYPFLKKMHKES-HVNSLVELIDIGGPSMLRAAAKNFLHVTAIIDENDYELVQNEIV-HYGFPSLKLRKKLAGKVFNFTSSYDSAISQYL---------LMDDMDEKFPIYLHSSYKKEMNLRYGENPHQKAAYYINT-IHHGAMRNFNQLHGKKLSFNNLRDMDIAWKVVSQFSEPACCTVKHSTPCGVALGKNIIEAFQKTYYADTISSFGGIMAVNVPITKELAKEI-NHIFLEVVLSPSYETDVLNILKIKKNLRIISINEPIS--DKLEYVQIDGGILVQETDYFFSHEENYKIVTQKKFTDQELKSLFFAQKVVKYVKSNAIVVAKETQTLGISGGQTNRIWAARQAIERALEKSKE--GLVLVSDAFFPFRDVVDEAARsgICAILQPGGSIRDEESVKACNDYGIAMAFTGKRHFKH
44 UniRef50_Q73LG8 Phosphoribosylaminoimidazol... 628 1e-178 1 42.3% 7:529 1:533 ------MGLVLASVSDKTGLKDFAFRLKAAGYDFIASGGTAKTLQEAGIKVKEVSEYTSSPEILGGRVKTLHPMIHGGILArtKEDRAELKALGFSGIDIVIANLYPFEKTISSPDSTESDCIENIDIGGVALLRAAAKNYSRVTVICDPADYDEVSSEIEKT-GEISLSLRKRLAIKAFDLCTRYDAAITSWLSGLSRLSGGIEEKTS------LTLCAYPGQDLRYGENPHQKAWLYTNE--PKAGPLGGKVLQGKALSYNNILDADAAWRAVSMFTKPAAVVVKHLTPCGLAenSEVSLALRAAIDCDPVSAFGSIIALNRPFDKASVEA-LGALFVECIIAPLFTEEAKELLSGKKNLRLIEAPILQEKEP-YEYKSVLGGFLKQEKDLGDPEGTEYKDAAERKAEPFERALLQFAMKACTMVKSNAILLakGFCSVGIGCGQPNRVDAARQAIERA---GERVKNSVLASDAFFPFPDTIEEAAKAGIKAVIQPGGSIRDYLSIEECNKHGMAMLITGVRHFKH
45 UniRef50_C2BRL1 IMP cyclohydrolase n=6 Tax=... 626 1e-178 1 43.6% 2:529 10:614 -DTQIPVKRALISVWDKTGLEQLAQALVEAGVQIISTGSTAKKIAAAGLPVTPVEDVTGFPECLEGRVKTLHPHIHAGILADRRKPDhqLQDLQVEPIDLVVCNLYPFEDTVA-SGADFDACVEQIDIGGPSMVRAAAKNHPSVAVVVSPYTYDAVIEAVQA--GGFDLHERRLLASQAFAHTAEYDAAIATWLDDQMTrdSADESDEDSAMPEWVELSGDRIASLRYGENPHQSAALYVDlsKPAPGIANAIQLHGKEMSFNNYTDGDAAIRAAYDHAEPCVAIIKHANPCGIAVAADVATAHRKAHACDPVSAFGGVIAVNRPVTVELAKQI-APIFTEVVLAPAYEPGAVKALASKKNLRVLRVTPPARG--ALEVRQISGGYLAQQRDDVAESGDcwTKVCGPDVDEATLRDLEFAWQTIRATKSNAILLAHDGATVGIGMGQVNRVDSCKLAVERANTLgeRARGAVAASDAFFPFADGPQILINAGVKAIVQPGGSIRDQETIDVCEKAGVAMFTTGVRHFFH
46 UniRef50_C1CWJ7 IMP cyclohydrolase n=2 Tax=... 625 1e-177 1 46.4% 8:529 3:510 -------KRALISVSDKTGVVEFARSLTARGWEVLSTGGTFQALQEAGVSVTQVSDVTGFPEMLDGRVKTLHPAVHGGILARREPQhsQLEAQGFGTIDLVCVNLYPFRETVAR-GAPDPEVIENIDIGGPAMIRSAAKNHSGVLVLVDPADYPVALQD------EVSGSERRRLAAKAYRHTSEYDAAITAYL-------EGASEELPTRLPERLTVDLHRVAQVRYGENPHQPGAVYRW-GQARGPVMDAQVVAGKPMSFNNYADADAAWSLCQEldGAVCVAVKHANPCGVAVADDVRAAWERARDADTLSVFGGVVAVSRPVDFQAAQA-MRGTFLEVLIAPEVTPDAVEWFAEKkdLRVLVAAQ-ASGVSVLDVRPLTGGFAVQERDTRPWDDLCPEVVTARQPTDQEWADLRFAWATVKHARSNAVVLARGGVTVGLGAGAVSRIWAAERAVANA---GDKAQGAVLASEAFFPFDDVVRLAAQSGVTAILQPGGAKRDPEVIAAANELGVSMVFTGSRHFRH
47 UniRef50_B8DUE1 Bifunctional purine biosynt... 621 1e-176 1 44.4% 1:529 1:549 MTTNRPIRRALVSVFHKEGIEVLAQAFIDAGTEVVSTGSTANKLAELGVNVIEVSQVTGFPECLDGRVKTLDPHIHAGILADMTNEDhqLEEFGIKPFDLVVVNLYPFADTV-RSGAGESDVIEKIDIGGPSMVRGAAKNSATVAIVTDPTDYALVATRIENGEG-FSLEERRWLAAKAFAHTAAYDATINEWTSAHWPKPASIDETIdgKFPAQYTRSWNRAHILRYGENPHQDAALYVDPLNVR-GFADAEQLGGKPMSYNNYVDADAAWRAVWDfpQIAVAVVKHNNPCGLAVGTTVAEAHRKAHACDPMSAYGGVIASNATVTLEMAEYIRS-IFTEVIVAPDYEPEALALLqkKKNLRILKVAEPP--KAKYQFKQIDGGLLVQSTDLIDahPDAWKLVAGEAADERTLKNLEFAWRAIRCVKSNAILIADDMATVGIGMGQVNRVDSAHLAVERadDGRNRTKGAVAASDAFFPFADGAEILIDAGVRAIVQPGGSIRDEEVFEAARKANVTMYVTGTRHFLH
48 UniRef50_Q2S222 Bifunctional purine biosynt... 615 1e-174 1 46.4% 2:529 4:528 -DAPSPVRRALLSVYDKTGIADFARRLRSLDVELISTGGTADTLRDAGIDVTDVADVTGVPEVLEGRVKTLHPALHAGILARreDDMAALDEHDYAPIDLVVGNLYPFSEAVQDPDADPETVMEYVDIGGPTMLRAAAKNHFDVGVVSAPDQYAAAADELEQNDGHLSAPTRRRLAEAAFAHTAAYDQDIDAHLSR----ASGADADGDGDLQPTYNVALPQAQSLRYGENPHQEGALYGDPSP------FYDKLHGRALSYNNLLDTSSALALIDEFRdpTCAILKHTNPSGVATADTLEEAWHQAFATDTQSPYGGIVVVNQALDQATAEAI-DEIFTEIVIAPEFEPGVLEFLTEQDRRRVVRAKQPARGTDRLDVRSVLGGLLVQTRDPALPPAAtwEVPTARAPSDDERADLDFAWRVAKHVKSNAIVYARDQATLGVGAGQMSRIDASELAVFKAEKSELDLTGSVVASDAFFPFADGLEAAANEGARAAIQPGGSIRDDDVIEAADAHDVAMILTGQRHFRH
49 UniRef50_B3DRY6 IMP cyclohydrolase n=308 Ta... 613 1e-174 1 44.7% 2:529 3:545 -NTNRPIRRALVSVFHKEGIEVLAEAFVKAGTEVVSTGSTAKKLAELGVKVTEVSDVTGFPECLDGRVKTLHPYIHAGILADMTNPEhqLEEFGIKPFDLVVVNLYPFADTV-RSGANEADTIEKIDIGGPSMVRGAAKNHATVAIVTDPADYALVASRVADGTG-FSLDERKWLAAKAFAHTAAYDATINEWTAKHWPKPASLdeVDSAKFPAQFTRTWDRAHTLRYGENSHQQAALYIDP-LNQTGFAHAEQLGGKPMSYNNYVDADAAWRTVWDMAPaaVAVVKHNNPCGLAIGATAAEAHKKAHACDPMSAYGGVIACNSKVTLEMAES-VRPIFTEVIVAPDYEPAALELLqkKKNLRILKVAEPPKGHEA--IRQIDGGLLVQDTDLINadPDAWKLVAGEAADADTLKDLVFAWRAIRCVKSNAILLAHDQATVGIGMGQVNRVDSCHLAVERAndGADRATGAVAASDAFFPFADGAQVLIDAGVKAIVQPGGSIRDEEVIEAAKKAGVTMYLTGTRHFFH
50 UniRef50_Q8A155 IMP cyclohydrolase n=80 Tax... 611 1e-173 1 39.9% 1:529 1:507 MSESKRIKTALVSVYHKEGLDEIITKLYEEGVEFLSTGGTRQFIESLGYPCKAVEDLTTYPSILGGRVKTLHPKIFGGILCRRdqDIQQIEKYEIPEIDLVIVDLYPFEATVA-SGASEADIIEKIDIGGISLIRAAAKNYNDVIIVASQAQYKPLLDMLMEHGATSSLEERRWMAKEAFAVSSHYDSAIFNYFDAGEGSAFRC--------------SVNNQKQLRYGENPHQKGYFYGNLD------AMFDQIHGKEISYNNLLDINAAVDLIDEYEDLTFAILKHNNACGLASRPTVLEAWTDALAGDPVSAFGGVLITNGVIDKAAAEEI-NKIFFEVIIAPDYDVDALEILGQKKNRIILVRKE--AKLPKKQFRALLNGVLVQDKDMNIETVADLRTVTDKAPTPEEVEDLLFANKIVKNSKSNAIVLAKGKQLLASGVGQTSRVDALKQAIEKAKSFGFDLNGAVMASDAFFPFPDCVEIADKEGITAVIQPGGSVKDDLTFAYCNEHGMAMVTTGIRHFKH
51 UniRef50_B9L973 Bifunctional purine biosynt... 611 1e-173 1 44.9% 9:529 2:504 --------RALLSVSDKTGIVDFAKQLVDLGFEIISTGGTKRILQENGIDAIDISEITKFPECFGGRVKTLNPYVHGGILYRSGIDDEEAEKLGITRIDLVAVNLYPFKETIERTD-DFDEIIENIDIGGPTMVRSAAKNFKDVLIVTDPEDYDTVVNALKEKKD--TYEFRRDLMIKAYEHTAAYDSMIANYMNER----------FNGGFGNKRFIVGNRVFNTRYGENPHQRGALYEFEDF--YKVLNIIK---GEPSFNNLTDINGAVKIAVSLGEGAISIIKHANPCGAAKKDDLVTTWQKALECDPISAYGGVVAVNGVVTKELAEEI-NKIFVEVLIAGTITDEAVKVFEKKKRIKLFDLRKPKLEIPgwDFKHIEGGFVFQDADVVTEDeaEAKCVTKVCV--EDKKDLEMAWKIAALTKSNCVVFVKDSQMVAIGMGMTSRVDATRCAVEKAKSLGLDITGSSLASEAFFPFRDSVDYAAEVGVKAIIQPGGSIRDDEVIEAADEAGIAMYFTGKRHFLH
52 UniRef50_Q7NN55 Phosphoribosyl aminoimidazo... 610 1e-173 1 46.5% 10:529 4:499 ---------ALLSVSDKTGLVDFARALveFEYQLISSGGTARALAEAGVPVQEVGDFTGAAEMLGGRVKTLHPKIHGGILARRDqdRRDLETHSIAPIDLVVVNLYPFEQ---------DPRIEQIDVGGPTMVRAAAKNHAFVTVLVSPGQYEGCLAELRRNRGVTTLPFRAACAAAAFARTAAYDRAIAAWFAGSEPV-----------LGERLVLELERVQPLRYGENPHQAAAWYR--HGPAAGWSTGRILQGKALSFNNLIDLEASRRLVAEFDdpAAVIIKHTNPCGVAADATIAAAYRRAFDADSASAFGGIVALNRPCDEPTA-ALLGQTFLECVVAPAFTLGALALLERKKNLRLLELADLT-TPPVFDVKPISGGFLIQQVD-APVRAEDWKVVTEAVPDEDQRAELLFAWKVCQHVKSNAIVVSHLRQTLGVGAGQMNRVGSARLALAQA---GEKARGAVLASDGFFPFDDTVRAAAERGIRAIVQPGGSLRDEDSIRACNELGVAMVFTGVRHFLH
53 UniRef50_A1VZU4 IMP cyclohydrolase n=25 Tax... 610 1e-173 1 43.6% 9:529 2:510 --------RALLSVSDKEGIVEFGKELENLGFEILSTGGTFKLLKENGIKVIEVSDFTKSPELFEGRVKTLHPKIHGGILHKRSDENhqAKENEILGIDLVCVNLYPFKKTTIMSD-DFDEIIENIDIGGPAMIRSAAKNYKDVMVLCDPLDYEKVIETLK--KGQNDENFRLNLMIKAYEHTANYDAYIANYMNER----------FNGGFGASKFIVGQKVFDTKYGENPHQKGALYEF---DAFFSANFKALKG-EASFNNLTDINAALNLASSFDkpAIAIVKHGNPCGFAIKENLVQSYIHALKCDSVSAYGGVVAINGTLDEALANKI-NEIYVEVIIAANVDEKALAVFEGKKRIKIfeSPFLIRSFDKYDFKHIDGGFVYQNSDEVGEDekNAKLMSQREASKEELKDLEIAMKIAAFTKSNNVVYVKNGAMVAIGMGMTSRIDAAKAAIAKAKEMGLDLQGCVLASEAFFPFRDSIDEASKVGVKAIVEPGGSIRDDEVVKAADEYGMALYFTGVRHFLH
54 UniRef50_C1N4E7 Predicted protein n=1 Tax=M... 606 1e-172 1 43.4% 9:529 42:625 --------RALISVSDKTGMTNLAAELAKLGYEVVSTGGSAKAISDAGVDVTAVDAITNYPEMLDGRVKTLHPAVHAGILARRDVAShaVTTHDIGYVDIVAVNLYPFRETVA-SGAGFERCVENIDIGGPAMIRAAAKNHPFVYVLVDAADYGPLIEHIKSNPSDAdlAMRKKLAWKAYQHCASYDAVVAEYLWSevPMTLADTLRYGARfpHVLtqSHPLVTDARlgENPHQAAAVYSDASLAEAgvGRATLHHGKEMSYNNYLDAEAAYSCVSDFpdPTCVVVKHTNPCGVacGGDVLEAYRAAVRADPISAFGGIVAFNCEVTEEMAKEIrtRMFYEIVIAPAYTEAGLATLKGkkNLRILEAKP---RTPSSTLRQVGGGWLQQQSDSLLPEDIEFTTVSKTQPTPDqiEALKFAWRCVKHVKSNAITVATKGRLLGMGSGQPNRVNSVRIALEK---SGEETEGSVLASDAFFPFadSVEKACQAGVKAIAHPGGSMRDQDAVDCCDKYGVALVVTGHRHFRH
55 UniRef50_Q2JI00 Bifunctional purine biosynt... 606 1e-172 1 47.1% 10:529 18:577 ---------ALLSVSDKTGLIPLAQSLveHGFQLLSSGGTAKALSEAGIPVTPVSAHTGAPEILGGRVKTLHPRIHGGILARLEcdRADLEALGIPPIQLVVVNFYPFEQTVAQAGVSLEEAFEQIDIGGPTLARAAAKNYPYVTVLTDPSQYPRYLQLLSGAYGEtrLAFRFQCARRAFEQVLAYDRAIVTYLARLELA--GPSQSSAAAAEDRFQLQGILWQRLRYGENPHQAATWY-VTDPAAPGWHRAKQLQGKELSYNNLlnADATrsARREFLQpvAVVVKHNNPCGVAIRPSPAAALEAALAADPVSAFGGIVALNQPLDAETARRLV-EPFLECVVAPDCTPEAAELLSVKKNLRVLILPDLCVG-PAQTIRTLAGGFLVQDADSPVasPPSWQVVTQRQPTPEEWADLEFAWIVCKHVKSNAIVVAKQRQTLGVGAGQMNRVGAAEIALQQA---GSQAAGAVLASDGFFPFADSVEMAAQAGIRAIIQPGGSIRDADSIAAANAAGIAMVCTGIRHFLH
56 UniRef50_Q8D244 IMP cyclohydrolase n=1 Tax=... 592 1e-167 1 48.9% 2:529 3:529 -QSFLPIRCALISVSDKTGIFSLAKNLIKHKVKLITTSGTYKYLLEKGIFSTSVSEYINHPEIINGRVKTLHPKIHGGILSNNKNIN-ENKNLNIKKIDMVITNFYPFKKKVKKENIKIENIIDNIDIGGVALARSAAKNYKYVTVVVNINQYSKLSSEMDKNSGSVSFKTRFYFSTLAFQYSYSYDKEIFNYFNKifKEIELKKNLKNKKFPELFSISFSKKEDVLYGENYHQKAAFYTDPVIHPGTVPFSIQRQGKKLSYNNIVDSDIAINCVMNFSEIACVIVKHSTPCGVSSGKNIIDAYRSAYYSDPDSAFGGIISFNRPLTIEAAEFIINKQFVEIIIAPVIEKDALLTLKSKSKIIVLECGYLSKNF-LLNFKKVNCGLLLQDSDNKILKEKDIKIVSKRQPSKLEIESSIFIWKIIKFIKSNAIIYGKNKRTLGIGSGQTSRIFSTRIAAYKAIDQGFSLKGSVMASDAFFPFRDSIDFASKFGVSCIIQPGGSINDDKIISAVDENNMSMIFTNTRQFSH
57 UniRef50_C7MFI4 IMP cyclohydrolase /phospho... 591 1e-167 1 43.1% 3:529 5:555 --DRRPIRRALLSVFDKTGIVDLARTLAETGVEIVSTGSTGRTVREAGIPVTEVETITGFPEMLDGRVKTLHPRIHGGILarLEAHRAQLADHDIAPFDLVVVNLYPFSETVA-AGGGFDEIIEKIDVGGPTMVRAAAKNFASLAVVVDPEDYATAAE--AASTGGFTLAERQELAAIAFTRTAEYDEAISDWMLEQLSGALAEGGAAEAAAGEDDEEEEVSVLdlRYGENPHQRARL-AVTDEDRPGLAGAEQLGGKEMSYNNYVDADAAVRAAFDHSLPAVAVVKHNNPCGVAvgEDIALAHRRAHGTDPLSAYGGVIAANRTVTLAMAQQ-VKPIFTEVILAPGYEDDALELLRTKKNLRILRLQ--GEYHHPVEMREIWGGMLLqaLDAAGDDPASWTLAAGEAADEGTLADLAFAWRSVRAVKSNAILLAADGAAVGIGMGQVNRLDSCRLAVSRANTLgeRARGAVAASDAFFPFADGAQILLDAGVRAIVQPGGSIRDEEVIAACQSAGVTMYLTGTRHFSH
58 UniRef50_Q6MIZ2 IMP cyclohydrolase n=1 Tax=... 578 1e-163 1 39.0% 5:529 2:507 ----NPIRRALLSVSDKTGLLELAKNLAAQNVELIASGGTAKALTEAGLKVTAVETLSGKGEAFNGRMKTISFEIASSLLFRreNDVRQAAELGIEPIDLVVVNLYPFHATLQK-QAGFEECIENIDIGGPTLLRAGAKNFHSVTVLCDPSQYSEFLKEFNGNNGSTTWEFRQKCAAAVYTMTAFYDMAIAGFLTQNSGAA------------------------LRYGENPHQKAVVLKDPFAD--GLAHAKSLQGKEMSYNNYLDADFALKTLQDVHrpAAVVVKHNTPCGMAVAETPLRALEKAWKGDEKSSFGGIIALNVPVTEDIA-AFFAEKFVEVILAPSFTEGAREKL--KKNCRVMEVSLKPN--PSMQVRSIEGGLLLQDAD--GFDLSHMKTVTQKQVSPEQQRLAAFAMLAVKNLKSNAIALCRQdeLLTMGSGQTNRIDCIeiTSRLADKGITDLTGVVLASDAFFPFADSIQVSAKLGVQTIIQPGGSVKDPEVIAEADRLGVSMIFTGRRHFLH
59 UniRef50_UPI000038E408 bifunctional phosphoribosyl... 576 1e-163 1 38.8% 9:529 2:500 --------RILISVYDKTGLVNFLSSIKDHIDEIYGTEGTVKYLKDNNIAANNSSNLTGFDDLLGGRVKTLHPAIFSGILSKRDSEsmQLEKYHYKDFDMVICNLYPFVE--ASKTDDLEKMIENIDIGGLSLIRAAAKNYKNVAVLSHPDDYSMVKDVLQKN-GKIDMKTREILGLRAFSRSADYDIQIYNKL----------YRKLNDRQPEELFIHGYDRTDLRYGENPDQEA--YMFKVNEKYGIPNSIQLNGKELSYNNILDANAALETVQDFQDITSVIVKHRTPSGVSSAGTLKEAFINSYNADPESAYGFVVALNRKLDMDTAKE-MQKKFIEVLIAPEYDTDALNLLKKKKNMRILKCSMDHD--PEKAIYSVSGGVLVQSR--LDYRYDNLELKSTAEAGKEKLADLEFAWKVVAHAKSNAMVLAKNRTTVGIGAGQTSRIESLKIAIERGNS---NVKGSVLASDAFIPFDDSVIECYKNGIDAIIQPGGSIRDDDVIKRCNEYKIPLYFTGKRVFLH
60 UniRef50_P31939 IMP cyclohydrolase n=52 Tax... 568 1e-160 1 39.1% 6:529 3:592 -----PGQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLGGRVKTLHPAVHAGILAriPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVVVSTEMQSSEsdTSLETRRQLALKAFTHTAQYDEAISDYFRKQ-------------------YSKGVSQMPLRYGMNPHQTPAQLYTLQPK----LPITVLNG-APGFINLCDALNAWQLVKELKepAAASFKHVSPAGAAVGIPLSeaYARARGADRMSSFGDFVALSDVCDVPTAK-IISREVSDGIIAPGYEEEALTILSKKKNGNYCVLQMDQSYKPDeeVRTLFGLHLSQKRNNGVVDKSLfnVVTKNKdpESALRDLIVATIAVKYTQSNSVCYAKNGQVIGIGagDKANYWWLrlIKWKakEWVEKLTEVSISSDAFFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH
61 UniRef50_Q1V178 Bifunctional purine biosynt... 561 1e-158 1 40.2% 10:529 14:518 ---------ALISVSDKKDLGSLLRVLAKYKIELISSGGTFKEIKKLKFKCQEVSEYTGSPEILGGRVKTLHPKIHAGILSKRNDKSheLKANQYDEIDLVIVNFYPFEKTLDQTTNHSK-IIENIDVGGPTMVRAAAKNYNDVTVITSSDQYETLINELENNKGSTSIEFREKMSLEAFSETAYYDAVISNYFNKI----------KKNNFPKKKIIYGNLIEKLRYGENPHQEAAIYSKTQN-----LNIKQIHGKQLSYNNYNDIFSALTISKSLPKNstVIVKHANPCGVSINKNSLKSYKLALASDPVSAFGGIVSCNFKINKTLALE-LNKIFLEVIIANGFQADALKILKKKKNIRIIDASEFMMK-DLIRFGSVNESILTQSEDLKVFEPKDFKVVSKLRPNKSQLKNLIFAFNVCRYVKSNAIVLASQEATVGIGSGQPSRLDSCQIAIDKMNKFQNLKEDIVAASDAFFPFVDGIEKLVQSGVSAVIQPSGSIRDKEIIKFANQTGTILVFSKTRHFRH
62 UniRef50_Q6L122 Phosphoribosylaminoimidazol... 555 1e-156 1 40.1% 9:529 2:494 --------NILVSVSDTSGLTDLLRHLNG---DVYATPGTFKFLSDSGIKAKRISDITGFDDLLNGRVKTLHPAVFSGILSRRdqSEADLKRYNYFDFDIVICNLYNFESYIDK---SIEDMIENIDIGGLSLIRAAAKNYQHVTVASSPEDYNIIIKDLRD--GEISLRTRETLALRAFARAAYYDMIIY----------KSLYKRLNNDEPEELFIHGYDRTKLRYGENPDQAGFLYR--TDDEYGIPNAVQLNGKELSYNNIIDADSALETVLEFDEPTAVIVKHRTPSGVSSADNIRDAFINAYSSDEESAYGFVLALNRKVDEETAME-LSKHYIEVLIAPDYDEPALNILKKKKNLRILKA--VFRRNNSYVFQSIPGGLLMQSP--LRSDFTEMKCMTIEA-DERTKKDLLFAWRVSAHCKSNAIVLAKNLTTTGIGAGQTSRIESLRIAVQR---SNGNAKGSVMASDGFIPFNDSIIEANKNGIKAIIEPGGSIRDNDVIQKAIEYKIPLYFTGKRVFLH
63 UniRef50_P31335 IMP cyclohydrolase n=95 Tax... 550 1e-155 1 37.1% 10:529 8:593 ---------ALLSVSEKAGLVEFARSLNALGLGLIASGGTATALRDAGLPVRDVSDLTGFPEMLGGRVKTLHPAVHAGILAriPEDNADMNKQDFSLVRVVVCNLYPFVKTVSSPGVTVPEAVEKIDIGGVALLRAAAKNHARVTVVCDPADYSSVAKEMAASkkDTSVETRRHLALKAFTHTAQYDAAISDYFRKE-------------------YSKGVSQLPLRYGMNPHQSPAQLYTTRPK----LPLTVVNG-SPGFINLCDALNAWQLVKELKqpAAASFKHVSPAGAAVGIPLSeaYARSRGADRMSSFGDFIALSDICDVPTAK-IISREVSDGVVAPGYEEEALKILSKKKNGGYCVLQMDPNYEPDdeIRTLYGLQLMQKRNNAVIDRSLFkiVTKNklPESAVRDLIVASIAVKYTQSNSVCYAKDGQVigAgaGDKANSWWLrlTEAEKKQWIAKLTAVSLSSDAFFPFRDNVDRAKRIGVQFIVAPSGSAADEVVIEACNELGITLIHTNLRLFHH
64 UniRef50_D1B9N7 IMP cyclohydrolase n=4 Tax=... 546 1e-154 1 37.9% 8:529 5:509 -------RYAIVSAYDKSNLEGLVRAIDRAGYRIISSSGTAKFIRSLGIQVTEVEEVTGYPHLFGGRVKTLHPKVAGGILFREAEDSEEAASHQVPRIDLVVCTLYPFEEA-ARAQAPIEELIEKVDIGGVTLIRAAAKNHRRVAVVCHPADYESVASEL-DSLGAVSPKTRERLAVKAFSVTAAYDGTISAVLSDRIGTGSPMKDASIART----AIPLWRVQRLRYGENPYQEASLW-----DRLGEPPFRLLGGKELSYNNILDSDAALRGILLFRDsaAVIIKHTNPCGAALGDTIGEALASAIDCDPVSAFGGIVGLTRPVDLQAAE-ILADRFFEVVLAPSFHPEALELLRSRrsLRLVEAT-----SPRMEvrDTLLGTLVQEDPIPVPPREEDGTWHGKRRPDL-WDDLVFAWKCAALAKSNAIAVAKGGRLLGLGCGFTNRVDAAAFALGKAGDA---AHGAAMASDAFLPFPDTVEVAHSKGVGAIIQPGGSVRDRDVIDRALELGLSMFMGGTRTFRH
65 UniRef50_B7GBN9 Predicted protein n=3 Tax=c... 540 1e-152 1 37.9% 5:529 16:615 ----VPVTRALISVSDKTGIVEFATFLASQNVHLLSTGGTAHQLRQAGLTVTDVAEYTGAVECLDGRVKTLHPKVHGGLLGVRGNPQheMQDNGIQNIDMTILNLYPFEQTV-NSGAPMAQCIENIDIGGPSMLRSTAKNHAFTTIVTSPDQYAKVQACMQQHGGTRLALRQALAAQAF-ALSAAYDSAIATWFSEQLTDNDANVPE------PVVARIYQPAFPLKYGCNPQQSPA----KILSRLGSKLPFDVKNGTPGYINLLDAANAWQLVLELQqaAAASFKHVSPAGAAVAVPLNdaYLRARNADPMCSFGDFCAVSEQVDEATAR-YLKKEVSDGIVAPSYTPQALEILKAKKGGKFIILEATPDYQPgfEYREVYGMTFSQKRNDVIIGKQHMENVVTAQ-KEMNVRDAIVASICIKYTQSNSVGFAKDGMMVGVGAGQQSRVDCVKLAGRKVATWYLRQHPKVLakDAffPFRDSIDHASKLGVSFVAQPGGSVQDDQVTEACNEYGMAMAFTGVRLFHH
66 UniRef50_C5L910 Bifunctional purine biosynt... 534 1e-150 1 33.2% 3:529 19:630 --SPIVVKTALVSVYDKTGLDSLGKCLASYGVKILSTGGTAKKMKDLGCSVMDVSEYTGSPEILDGRVKTLHPKVHGALLAVRGNEShqLVELGIEKIDLVVVNLYPFEDAVASMSSDFSACIENIDIGGPCMIRAAAKNSHGVCILTSTADYDELARELAMNKGSTTPEFRRRMACKAFALTARYDSKIAAYMSSVADSTETLAGS--------VTQAFDVVSPLKYGCNPHQQPAAMC--SVVGNGGAMPFKVLNGTPGYINLLDAINSWMLVREMDtpSAASFKHVSPAGAAVAspVALAYIRSRNGDPMCSFGDFVAVSRTVDVSLA-SLLKSDVSDGIIAPGYEPEAYEILKAKKGGKFVILHGDTNfcPEIEVRSLGGLGLLQKRNDIIFDSSYLqiVTKasFTQQQIIDLIVCSIAVKYTQSNSVGFCKDGMMIGIGAGQQSRVDCVKLAARKVQNWWHRQHPKVLG----MKFKSSVKKQARVNArdVPEpgVAVSSddSIDVCSRYgmTMAFSSLRLFHH
67 UniRef50_C7M2P6 IMP cyclohydrolase n=1 Tax=... 530 1e-149 1 38.0% 7:529 1:497 ------MARALISLYDKAGLERVARPLHAAGWRIVASGGTGEALRGLGVPFEPVEELTGFASMLDGRVKTLHPAVFGPILADLERPHhtLEEAGWEPIDLVVVGLYPFAS---------DPSVDLIDIGGPSLVRAAAKSADRVTVLVDPADFGLVDEVIAGN---VDRPLRRRLAAKAFATTSAYDAAVATWLGG-----------GEGSLPDPLVLPLERVAVTRYGENPHQRGALYAPIGTRR-GFAEARWHGGLEPSWLNIADADAAARLVARlpEPAAVVVKHAGPCGAAVAPTLAEAYELAFAGDPVSAFGGVVALGGVLDVAVAEALLAHPKADVIVATAIDDdaQALLARRPKTRLVELAID--RDEPWWVRSVAGGVLVQEPD-QLEEPTDLELVTSRVPTDEERRDAWIAHVVCASTQSNAVVIARQGAVVGVGQGQPSRVDAARLAVGRAGARAQGGA---AASDAFFPFPDGLETLIDAGVTCVVAPAGSVRDDEIRAVAEGRGVSLLVAPRRHFRH
68 UniRef50_P54113 IMP cyclohydrolase n=15 Tax... 528 1e-148 1 34.0% 8:510 6:506 -------KTAILSVYDKTGLLDLAKGLVENNVRILASGGTANMVREAGFPVDDVSSITHAPEMLGGRVKTLHPAVHAGILArlEGDEKDLKEQHIDKVDFVVCNLYPFKETVAKIGVTVQEAVEEIDIGGVTLLRAAAKNHSRVTILSDPNDYSIFLQDL-SKDGEISQDLRNRFALKAFEHTADYDAAISDFFRKQ-------------------YSEGKAQLPLRYGCNPHQRPAQAYITQQEE---LPFKVLCG-TPGYINLLDALNSWPLVKELSapAAASFKHVSPAGAAVGLPLSdaYARARGADRMSSFGDFIALSNIVDVATAK-IISKEVSDGVIAPGYEPEALNILSKKKNGKYCILQIDPNYVPgmESREVFGVTLQQKRNDAIINQSTFkiVSKNKatEQAVIDLTVATLVLKYTQSNSVCYAKNGMVVGLGAGQQSRIHCTRLAGDKTDNWWLRQHPKVLN----MKWAKGIKRADKSNAIDLFVTGQRIEGPEKVD-------------------
69 UniRef50_P38009 IMP cyclohydrolase n=115 Ta... 527 1e-148 1 33.3% 8:500 6:496 -------KTAILSVYDKTGLLDLARGLIEKNVRILASGGTARMIRDAGFPIEDVSAITHAPEMLGGRVKTLHPAVHGGILAriDSDEKDLKEQHIEKVDYVVCNLYPFKETVAKVGVTIPEAVEEIDIGGVTLLRAAAKNHARVTILSDPKDYSEFLSELSSN-GEISQDLRNRLALKAFEHTADYDAAISDFFRKQ-------------------YSEGQAQITLRYGANPHQKPAQAYVSQQDS---LPFKVLCG-SPGYINLLDALNSWPLVKELSapAAASFKHVSPAGAAVGIPLSdaYARARGADRMSSFGDWIALSNIVDVPTAK-IISREVSDGVIAPGYEPEALAILSKKKGGKYCILQIDPNYVpaVERRQVYGVTLEQKRNDAIINQSTFkiVSQNklTEQAIIDLTVATIAIKYTQSNSVCYARNGMVVGLGAGQQSRIHCTRLAGDKADNWWFRQHPRVLE----IKWAKGVKRPEKSNAIDLFVTG-----------------------------
70 UniRef50_Q9X0X6 IMP cyclohydrolase n=9 Tax=... 478 1e-133 1 34.2% 7:529 1:452 ------MKRILVSLYEKEKYLDILRELHEKGWEIWASSGTAKFLKSNGIEANDVSTITGFENLLGGLVKTLHPEIFAGILGPEP------------RWDVVFVDLYPPPD---------------IDIGGVALLRAAAKNWKKVKPAFDMETLKLAIE-------IDDEETRKYLAGMTFAFTSVYDSIRAN------------------QFVEGISLAFKRelQLRYGENPHEKAFVY-------GKPAFEILHEGKTISFNNILDAENAWFMAKNLPRMGAVVVKHQSPCGAAIGEDKVEIVKKAIEADDESSFGGILAVNFEMDEEVAKSL--KKYLEVIVAPSFTQEAIEVLSKKK-VRLLKPGDYASWAGKMAF----GSLVLSERKYP---EGNFELVVGEPLSEKELEDLEFAYRVVEGAKSNAVLIAKDGVTVGIGSGQPSRKRAAWIATVMA---GEKAKGAVAASDAFFPFPDSLEILAQAGVKAVVAPLGSIRDEEVIEKARELGITFYKAPSRVFRH
71 UniRef50_A0B9A9 Phosphoribosylaminoimidazol... 460 1e-128 1 41.8% 130:529 61:451 ---------------------------------------------------------------------------------------------------------------------------------GRLLIRSAIHGGGAVLECGDNDMLEAISRDLN-----LADDVKRLASASALYRCMAFDA------------SELHALQSDMYWPKYSVSLFEKVQDLRYGENWHQRAALYARPG--GLGLFRAVKLNGKEMSYNNFVDAETVLEMLIDLSepLAVIVKHANPCGVAYGSDLEEAYRWAFATDPKSAFGGVIGFNMKVDLATAEAI-GDSFVEVLIAPGYEPDALELlrNKPNRRILDIGDMLQRKDElaFRSVFGGMMLQDYDR--EDILEWRVVTQRSPTPEENRALRFAWKVTKYVKSNALVYTTADRTIGIGSGQVSRVDSARFGAEKAEEHGLDTRGTVAATDSFFPFRDGLDRVHEAGATAVVHPGGSIRDREVIQAADEHGMAMVFTGMRHFRH
72 UniRef50_D2RX69 Phosphoribosylglycinamide f... 444 1e-123 1 45.0% 152:529 168:544 -------------------------------------------------------------------------------------------------------------------------------------------------------DDEETLKERVLYEGEFRAYPR---AVKWFADGadVDLEAGEVTVENDVATVGDDDH--DGLPTRRLVSDDRADTLRYGENPHQDAAVYADYTTDEASVVHADQLnaKALSYNNYNDADGALNLIKEFDEPSAAVIKHTNPAGCATADSLAEAYEKALSTDPMSAFGGIVALNRECDAATAEQII-DSFKEVVVAPGYTDDALEVLFEKDNLRVLDVGELGERTERFTEKPLVGGRLVQERDLQSISVDDLEVVTEREPTDEELESMVFAWQTLKHVKSNGILFVDGTETVGIGMGQVSRVDAVRLAAMKADeeGKDAEGAVMASDAFFPFPDGIEEAAEAGIEAVVQPGGSVNDDDVIEAADEHGIAMAFTGQRSFRH
73 UniRef50_B0R3B2 Phosphoribosylglycinamide f... 404 1e-111 1 43.9% 161:529 167:537 ----------------------------------------------------------------------------------------------------------------------------------------------------------------DDTAATLKTRVRQDAEFEAYPR--AIRQFAAGELDATTDGVSRADSDDAATFPARRLTGTTREDVLRYGENPHQDAAVYRDNTHAAASVVHADQLnaKALSYNNYNDADAALALVREFDdpAAAVIKHTNPAGCATADTLADAYSDALSTDAKSAFGGIVALNRECDAETATR-VADSFKEVVVAPGYTDDAVDVLTAKSNLRVLDVGTLDGTPAPVTETPLVGGRLVQERNTWAPTADDLEVVTKREPTAAEVETMLFAWRVLTHVKSNGILFAAGTETVGLGVGQVSRVDAVEIAAKKAErnGKTADGAVMASDAFFPFPDGIAAAAEAGIEAVIQPGGSKNDDQVIEAANEHGMAMVFTGHRAFRH
74 UniRef50_C9RNY6 IMP cyclohydrolase n=1 Tax=... 389 1e-106 1 45.6% 214:529 3:350 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EELVLKFVDPQPMRYGENSHQSAVFYRDPTCTEANLASAKQLWGKELSYNNIVDADAALEMAREFSdnAVVIVKHMNPCGLATGETLREALEAAWAGDPVSAFGSVIAVTRKVDLKTAE-FLKGKFVEILLAPAFDDDALKFLKNkkDIRLLEVGEIKKATACKVYKHVIGGMLVQDRDIG--TWEKFECVTKAQFPKNKEDLARFTWLVTKHTKSNAIVMCYEyqVMGLGPGQPNRIDsaRlaGLKALEKKV-FGEVVMGSDAFFPFPDNVEAAHDAGVRYIVQPGGSKKDDLSIESADKFGIAMVFTGMRHFRH
75 UniRef50_B6VSS1 Putative uncharacterized pr... 347 6e-94 1 30.7% 214:529 29:425 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PKYYKTMAKELELKYGCNPNQKPSRIFMQE----GELPIEVLNGR-PGYINFLDAFNSWQLVKELKepAAASFKHVSPAGAAVgtSLATAYARARGADRMSSYGDFIALSDTCDEATAR-LINREVSDGVIAPNYTPEALEILKNKRKGTYNVIKIDPAYRppIEHKDVFGITFEQGRNEIKLDESLLtiPTKSqfPDEAKRDLIIALITLKYTQSNSVCYVKDGQVIGIGAGQQSRIHCTRLAGNKADIWYLRQHPKVMnsDdffpFGDNIERAHKSGVAYIAQTGGSVRDDHVIDTCDKYGITMAFTGIRLFHH
76 UniRef50_D2LA78 IMP cyclohydrolase n=1 Tax=... 337 9e-91 1 36.6% 186:529 8:425 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YTTMVEDPFPAELAIRLGDAELTFAK--RTWTIDGEEKG-LRYGENPDQPAALytFRGPGDGLVCAATEEhgKHPGKTNLTDVDNGVNILQYlaKPAAVILKHNNPCGAAWSDalAVAFEAAFTADRIAAFGGAVVVNRTLDVATAEQI-NAVYVEVVAAPDYEPKALEILKSKKNLRIFRLPGLSqgQPFLDVKSldGGLVLqdFLPAQATDKAGTTVVARAPSAQEAEDLLFAWAVEAGVTSNSVIFVKDGATVAIGTGEQDRVGVVELTIHKAKTKYAdlAGTVLVSDGFFPFRDGVDLCIAAGVTAIAQPGGSIRDTEVIAACNEAtvAMVFTGQRSFRH
77 UniRef50_A6DLC7 IMP cyclohydrolase n=1 Tax=... 336 9e-91 1 36.0% 194:529 1:368 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEKTLSRSAYLNRNEGSYEDQLVIcyTKVDDLRYGTNPHQTAAFYKPAGLESPIGDLKVLKNGKslSQTNLEDISYALNIVKFFDEPTCAVMKHVNPSGAATAANVYDAYIQARDADPRAAFGSTIAFNSTVDEATAREIMSS-FVECVVAPTVSEEAMAVfkMNKSIRILQCGDLKnrYTGEEEARHNTLKTLADGSVVVAAptSLKSVADLKpsEQEKKDLLAAWYFNINVRSNGVVLVKNGTTVSVGTGEQDRVGAIEQAIAKFkeGEEDIQGSVMSSDGFFPFSDGVETAATAGVTAVIAPAGSLKDADVIKRANELGVALFHAPERIFSH
78 UniRef50_B5JGV5 AICARFT/IMPCHase bienzyme f... 334 6e-90 1 22.5% 9:523 4:474 --------RVLILVKEISGVAALASALVefGYEVLAIAAAGEVLGAKGISFELVDE----------------------------AKAAALVADKAAGVSLVVANFVD-VESAGRTFMSWKSALGAFDRGIVDTIRGAAWAVDRMAVLGNPADYDAALEELRGNGGKFRQAFRMERATAALRAASEFDFAVAQYL--EVQGADAPDMGALSGYSKAMRFAWPRAQFLDTGENAHQRAALY------GGFFEHFKQVSGKDLDYVGVLTVSRAAYLIGEFEKPAAALLRNGKIVTARCGQDLEVVLAGVLACDDLS--GSWLVANGSVGVGNLNTAISGD-VAGVLAPDFSEEEKAVLAEAKDVRALASISGMGYEALQEVRSVVGGVLVQDKDRAAINPMEWTVASLAQPLVEDWESLMFGAKVARHGDSAALVIVSGEQLVALAAGHYS----TDRAWLSVEESGIGLANTVAVFDDPNVGGETLARMKELGVRAVLVPFGG---DEvrEAANECGLVVLVIG------
79 UniRef50_Q726E7 Phosphoribosylaminoimidazol... 325 2e-87 1 36.0% 186:529 92:510 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YRTLQQDDFPERMTISFGDRTLVYRK--RTWVIDGEAKG-LRYGENPDQPAALYefRGPGQGLVSALTEEhgKHPGKTNLTDVDNGINMLQYlaRPAAIILKHNNPSGAAWSDaiADALSKAFWSDRIAAFGGAVVLNRPLDKAAAE-LIAANYFEVVAAPDFEEGALDIIKARKNLRILRIPGLARLepFLDVKSldGGIVVQHsdFLPATATSKetVTARAPSKQEAEDLLFAWAVESGVTSNSVIFVKDGATVSIGTGEQDRVGCVELAIHKAYTKYAdlIGTSLVSDGFFPFRDGVDCAVAQGVAAIAQPGGSMRDHEVIMALNEAtvAMVFTGQRSFKH
80 UniRef50_D2Q0V6 IMP cyclohydrolase n=1 Tax=... 322 2e-86 1 33.0% 224:529 1:353 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHLRHGMNPHQPATV------TPLDGSPITVLHG-APSYINLLDALNAWQLVRtfARPAATSFKHVSPAGAALAGPLDeaYARARDADPKSSYGDFGAVSHPVDPELAE-LLRRLSCDGVIAPGYDESVVGTLSAKKRGGFLVLAVDPAYEPpeEVRDVYGLRLTQHRDDLPLTRDLL----DPALPDAAARDLLLGLIVLRYTQSNSIALVRDGMTIGIGAGQQSRIDCTRLAGAKADTWWLRRHPSvmVSDGAIPFADNIDEAARHGVRTLAEPGGSLRTPEVVAACAAHGITATQTGVRLFHH
81 UniRef50_UPI000196B293 hypothetical protein CATMIT... 321 4e-86 1 32.4% 221:529 66:457 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKELELKYGCNPNQKPA----KVFMEEGELPFTVLNGK-PGYINLLDAFNSWQLVKELKEAtaASFKHVSPAGVAIGTPLTeaYIKARGSDRMSSYGDFCALSDVCDEVTAK-LINREVSDGIIAPGYTKEALEILKKKRRGTYCVLQMDPHYVppVEIKQVFGITFQQGRNNCVINEEMFkvVSKNKdpEHALHDLILSMITLKYTQSNSVCYVKNGQAIGIGagNKADVWFLRqgLKRAEknYFKVKpvVLGSDAFFPFGDNIERAHKSGVKYVGEPGGSIRDDHVIDTCNKYDMVLAFTHQRLFHH
82 UniRef50_D1VK19 IMP cyclohydrolase n=1 Tax=... 315 3e-84 1 30.1% 224:529 1:377 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNLRYGMNPHQRPATVEPLD----GTAPVRVLHG-EPSYINMLDALGGWQLVRelGRPAAASFKHVSplGPGPAGALTSAYVRARDTDPKSSYGDFAAVSAPVDAELAD-LLRRLVCDGIVAPGYEPGTVATLSAKKNGAFVVLEADPAYQPpqEVRDVCGLRFVQPRDDAVLDRTTLADVQVGTVPDGARDDLLLGLIVVRHTQSNSVAYVRDGMTLGVGAGQQSRVDGVRLAGAKTDTWWLRRHPRVQaeDGTGpfPDNIDHAHRHGVRYIAEPGGSTRSADVAAACQDRGIALIHTGLRLFRH
83 UniRef50_C9KQD2 Purine biosynthesis protein... 301 7e-80 1 30.4% 221:529 1:391 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKELELKYGCNPNQKPARVFMEHDAE---LPFTVLNGR-PGYINLLDAMNSWQLVRELRepAAASFKHVSPAGAAVasPIATAYIRARGADRMSSYGDFVALSDECDAQTA-SFLKREVSDGIIAPSYSPEALEILKSKRKGTYLILQMDPAYQPalERKQVFGVTFEQKRNNVAITEDCLkiATKNHdpENAKRDLLIALITLKYTQSNSVCYTKDGQAIGIGAGQQSRVHCTRLAGTKADNWFLRQSPQVLN----LPFKPEVRRPDRDNAIDVyeTGVSLGSddNIEraDKYNMTMAMTHIRLFHH
84 UniRef50_A7HM64 IMP cyclohydrolase n=2 Tax=... 274 6e-72 1 41.1% 7:264 3:247 ------IKRALISVSDKAGLVEFAKNLVDRGVEIISTGGTAKLLSDAGIPVKQVSDVTGFPEILGGRVKTLHPKIFGGILADLGDKSHVKDLRdiEPIDLVVVNLYPF-DEVQKKTRDEDVLIENIDIGGVALLRAAAKNHRNVVVVCDPADYDKVIKSIDLC-GDVQLHDRRMFALKAFYHTMKYDATIHRVLSELFASEKFEHMTFERFipQFDYEILDKVED--------------KFIRLSKYTKNASSIVAGAILSYIN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
85 UniRef50_B9LYZ1 Phosphoribosylaminoimidazol... 270 6e-71 1 27.0% 223:529 2:388 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EIKLKYGCNSHQTPANLIIPENSG------FQVLNGTPSYINILDALGAWQLARElsKPGAASFKHTSPAGAAVasPVATAYVRARGGDRMCSFGDVAAVSDIVDVSLAN-VLKSEVSDLIIAPGFEPAALEILKAKKQGTYLILQIDPDYEPaiEQREVFGFGLQQKRNTAPVSAALFQnvtgKSVSPDITETLIVATIALKFTQSNSVCLAYEGQVIGMGAGQQSRVHCTRLACDKADKWLLQQHPKTLN----LAFREGLKKPDKANIVdvKqpGICLSSddNIDRAnqYDMTMLHTGLRLFLH
86 UniRef50_UPI00005A1538 PREDICTED: similar to 5-ami... 269 2e-70 1 27.4% 162:529 4:401 -----------------------------------------------------------------------------------------------------------------------------------------------------------------SNSKDTSLETRCQLALKAFIHMAQYGEAISDYFRRQ-------------------YSKGISQMPLRYGMNPHQTPAQLYTLKPK----LPVTVLNG-APGFINLCDALNAWQLVKELKepASASFKHVSPAGAAVGIPLRevYDL-YKTLTLLHMQEQEGLMGCLHLVTLLHYL--MFVMSLLSKLSREIDQSYIQMKTNF------------------ELSGLRLSQKRNNGVIDRSLfnVVTKNKDleSALRVLIVATIAVNYTQSNSVCYAKNGQVIGTGagEKANCWWLrlIKWKakEWVDKLSEVSISSDAFFPFRDNVDRAKRSGVAYIAAPSGSAADKIVIEACDELGIILAHTNLWLFHH
87 UniRef50_C9KPE7 Phosphoribosylaminoimidazol... 265 2e-69 1 54.4% 6:200 2:197 -----QIKRALISVSNKQGVVDFARKLHEAGVEIVSTGGTMKAIKEAGIPVTYVSDVTGFPEIMDGRVKTLNPYIHGGILAVRDNPEheMEEHHITGIDLVAVNLYPFKETIAKPNVTLAEAIENIDIGGPAMVRAAAKNFKFVTIVTNPARYDAIAEQVTKN-GCVDDRTRMELAQEAFAHTAAYDTMIKDYLAEQLKK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
88 UniRef50_A0LLY6 Phosphoribosylaminoimidazol... 262 3e-68 1 60.8% 6:194 3:193 -----PVRRALVSVTDKSGLVDFAKGLSELKVRMLSTGGTARTLREGGIAITEVSDYTGFPEMLDGRVKTLHPKIHGGILGIRDNEAhtMAAHGIEPIDMVVVNLYAFAKTVARPGCTLEEAIENIDIGGPTLIRAAAKNNRHVAIVTDPGDYPDILRELRERKGFISRETSLRLACKAFCTTHTYDGNICEYL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
89 UniRef50_O85385 Phosphoribosylaminoimidazol... 258 4e-67 1 50.0% 64:277 1:205 ---------------------------------------------------------------MDGRVKTLHPKIHAGLLARRGIDEKTLDQHAIKPIDLLVVNLYPFVQTVSASNCSLEKAVEQIDIGGPSMLRAAAKNFAAVTVVVDPEDYSRILEEIKTHHGSTTLSTRKRLAQKTFEHLSYYDAHIATYLAEKEGAT---------TLPARLPSIFKKKIDLRYGENPHQTAALYSIDPPLSHSLAEAQLLQGKPLSFNNLLDSDCAYRAFYE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
90 UniRef50_Q95QQ5 Putative uncharacterized pr... 255 3e-66 1 27.2% 251:529 1:420 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPIKVLNGSPGYINILDGLNGWQLVKELSdpAAASFKHVSPAGAAVGLPLNeaYARAReaDRMSSFGDFIALSEKCDELTAK-IINREVSDGVVAPDFDPAALSLLAKKKNGNYCVLKINPNYLPSeeERTVFGLRLRQKRNNAVINAETFNNVVGsqLNKQAIDDLIVATIALKYAQSNSVCFAHRGQVIGMGAGQQSRIHCTRLAGDKAMNWWLRQHPTVLS----LPWKNAIKRSEKSNAIDVLCSggsaEDddNVDCAKqhGITLIHTGLRLFHH
91 UniRef50_Q316G8 Phosphoribosylaminoimidazol... 243 1e-62 1 51.8% 3:199 55:252 --DFLPIRRALLSVTDKSGLVEFATFLTQNGVELVSTGGTQRTLTEAGLDVTPVSKVTGFPEIMGGRVKTLHPHIHGGILADKDNPEhtLKELGIRTFDLICVNLYNFADAAAR-GLDLRGAVEEVDIGGPCMLRATAKNFHSMLVLPDPADYQAAMQEMRDNDMRVGLAMRQAMAVKTFRATSAYDGMIADYLGSKTA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
92 UniRef50_A9BI63 Phosphoribosylaminoimidazol... 238 5e-61 1 35.3% 7:247 3:231 ------IKRAIISVYDKTNLEDLASFLYRNGVEIICTEGTNKYLQEKGIPTVKMADYIGFPEILGGRVKSIDPKLAGGILAKSNDKKhdMINYNIKRIDMVVGNF-PTFEEIAKKTKNEETLLENIDIGGYSLLRAAAKNYKDVVALADPKDYQTVIDNLEDC-GDVPLQLRRKLALKVFFSTSKYDASIHKIFSELFAAEKFDHEF------------FEILGNLRYGSNPMQEAILMKFLEKDTF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
93 UniRef50_C0GRQ8 Phosphoribosylaminoimidazol... 230 9e-59 1 45.4% 3:198 2:197 --QLLPVKRALVSVTDKTGITELGQFLSSMEVEIISTGGTKKMLQDSGVTVTSVSDITGFPEILGGRVKTLHPHIHAGVLADKDNPEhtLDSMNIQPIDIVCVNLYAFEQAVQ-DDPGIEKAVEQIDIGGPTLLRAAAKNHASICVLPDPEFYQPCMDMLRDKKG-IDLDFRIKTASFTFAKTSRYDQVISGYFNQKI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
94 UniRef50_B8FDY6 Phosphoribosylaminoimidazol... 228 3e-58 1 41.1% 2:210 10:227 -DDPVQIKHVLMSVSDKTGLETFVPGLLEagVKIFSTGGtaEILGDKAKGceAVSDYTGQPETQGGLVKTLDFKIYLGLLTETYNDShdLKRTNGVPIDMVVVNLYPFRETIAQPKVTPEMARGQIDIGGPCMIRASAKNFLRVSSVVDPDDYPMILDELKANSGSTTMRTRYRLARKAFRHTASYDKAIADYLQETPFDNARPCYKFED-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
95 UniRef50_A8IVF0 Aminoimidazolecarboximide r... 226 1e-57 1 40.2% 262:425 254:425 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HNCPLDADAAYQCCCDYTEPSCVIVKHTNPCGIASRADLREAYRLAVRADPISAFGGIVAFNRPVDAELAREIrtKMFYEIVIAPGYTPDGLEVLKGkkNLRILEAQ--PRAPSGLSLRQVAGGWLWQDADSLQPEAITFTCVSEAQPTQQQLEDLKFAWRWVR--------------------------------------------------------------------------------------------------------
96 UniRef50_D1NEG1 Bifunctional purine biosynt... 191 7e-47 1 79.0% 425:529 154:258 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EFVKSNAIVYAKDNQTIGIGAGQMSRVYSAKIAGIKAQDEGLEVAGCVMASDAFFPFRDGIDAAAKVGIQCIIHPGGSMRDQEVIDAADEHNMVMVLTGMRHFRH
97 UniRef50_A8M123 Phosphoribosylaminoimidazol... 181 6e-44 1 38.2% 10:200 3:190 ---------AVLAVSDKRNIEELATGLLGLGWDVVATEGTRRLLRDHGVTVGAVSDLAGVPTLLGGRVKTLTVSLMGGILArePADRAEVERHGLTRVHLVCCNYYRLPD--PQPAQPFERFRELIDVGGPAMLRAAAKNCAHVVPLSDPDDYAGVLKALAD--GGVDRRQRLDLARKAFAVSAAYDTSVAALLAGAVNG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
98 UniRef50_D1JEE9 Putative uncharacterized pr... 163 1e-38 1 38.6% 9:197 2:168 --------KALISVYNKDIVVEFARALNERGLEIIATEGTARLILDNGIPVTKVSAFTGVQEMLGGKLKTLHPTIHAGIAT--------------GAIEIVTVNLIPL-------DISSENTLDNMDLGGVAMLRSGIKNFEHVAVIVNPARYKGIIEELRI-KGEIARDTKLSLAKDASKYIVAYESKINVILERM--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
99 UniRef50_C5CD72 AICAR transformylase/IMP cy... 153 2e-35 1 22.3% 7:244 3:221 ------IHKVFVSARITDGLENLCSKLISKGAEIIADESTYAFLKLKKITVKNLREFFETEVADD-------FALQRRilSGANEEKATCGSNN-KHIDLLVVNFEPFSTYVEKTGNETE-LVEHIDSFKPSLVLSAAKNYRNVVVLCDPEDYEDVLEDLE-YYGDVSLQRRRKLALKALYLLSAYTSEIYSVFSEIFAEE------------KYNYLILEKIMPLMFGEMSLKKSTLYKVSGI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
100 UniRef50_O28464 Inosine monophosphate cyclo... 130 2e-28 1 28.8% 9:199 2:157 --------KVLISSSVKEGIECLAKRLAEMGYEILATEGTADYLQEKGVNALKLSEITGIAESKS--IKTLHPKIYEMIFS--------------GEIKAVVVIPYNLREN---------PCRENIDIGGISLLRAAAKAGVPAAY--DLKSFQKLVEVLEGK--------KRYNAAEVFRFTSEYDRTIAEWLENEAP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
101 UniRef50_D2RG70 MGS domain protein n=1 Tax=... 129 3e-28 1 28.7% 9:175 2:133 --------NVLISVSRKDKLERFAKALVNLGYTLYATEGTAKFLENCGIPVRRLSEITHLSESED--LKTLHPEVFKRIYG--------------GFFSLIVVNLY----------------EDKVDVGGVALIRAGIKAG--VPVVCYPEDYEKVLEDLK-NGRDLSWLDLKAL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
102 UniRef50_C5LB27 Bifunctional purine biosynt... 128 5e-28 1 45.8% 423:529 145:320 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VSMHQDSncVGFCKDGMMVGIGAGQQSRVdsARVRYIEGDMSGLelTGVAVSSDAFFLFRDSIDVCSRYGVTSVMQPGGSVADTEVIEACDQHSMTMAFSNLRLFHH
103 UniRef50_A5N885 Conserved protein n=1 Tax=C... 127 1e-27 1 41.3% 455:529 16:90 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLTKEEKTSWLFNLSGVCLASDAFFPFRDNINRASQSGVKYIVQPGGSLRDDIVIDACNKYNMVMAFSNIRLFHH
104 UniRef50_UPI000169578C bifunctional phosphoribosyl... 122 3e-26 1 40.2% 381:507 14:137 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TVEGGTLVQDSDIXGLCVXALXVVXXRXPPVAXXXPLLFAWXVVXLVXSXAFVLARXXLXVGVGAGXVXRVGSARXALXPA---GAXARGSVLASXAFFPXGXPLXLAAXAGXXAVXPPGGSLKDED----------------------
105 UniRef50_P07259 Aspartate carbamoyltransfer... 118 4e-25 1 18.6% 4:175 1357:1538 ---KLPKKNILLSikEKQELLSSVQKLYNMGYKLFATSGTADFLSEHGIAVQYLEVLNKDDDDQKSEYSLTQHLANNEIDLYINLPSANRFRRPASYvrRLAVDyvPLVTNVKCAKLLIEAISRNidV----SERDAQTSHRTITllINIATYVPNASHVIKGPAELKETTRLFL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
106 UniRef50_Q58776 Carbamoyl-phosphate synthas... 118 8e-25 1 21.9% 2:129 475:600 -NMELPigNVFISVRdkKHIVDVAKKLHELGFTIYATEGTAKVLRENGIPAILVKKISESPN--DNILKLMR---DGKMHLIINTSSGKKAKSDGYYIRRAAVDliPYITTIPGAKAAVK-AIEAVKTG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
107 UniRef50_Q9RII6 Phosphoribosylaminoimidazol... 117 1e-24 1 41.3% 346:437 2:96 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PSYSEEALAILtkKKNLRILELPFDAQAASEVeyTGVVGGLLVQNQDVVAENPSDWQVVTDRQPTEQEATALEFAWKAIKYVKSNGIIITND--------------------------------------------------------------------------------------------
108 UniRef50_O67233 Carbamoyl-phosphate synthas... 114 9e-24 1 22.8% 4:126 397:516 ---RLpkGNLFISVAdkPKILELAKEFEKLGFGIYATSGTYKFLKEHGVNAKRVLKveGRPNVVDMI-------INGEIHLVINTPSGKREKSDAYYIRRACVQfvPYYTTM-RAGYAVLEAIKSI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
109 UniRef50_B9P6B2 Aminoimidazolecarboximide r... 104 6e-21 1 40.2% 412:513 8:103 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QVLRQQIFNSAV---VKSN--VITKNNCMLGRGNGQSNRLESLRISMRKA---GDEVKGASLASDAFfaWNDTVEKVCEVSIGVVAEHGGSIRNKDTIECCN----------------
110 UniRef50_C9RNJ8 Carbamoyl-phosphate synthas... 104 7e-21 1 22.5% 10:160 937:1072 ---------VLISLSDkeQAIEIGKEFQKLGFKIYATEGTAKFYEAAGVKCEVVNKieGRPNVLDII---LNKQVNLIINTPWAKRDAIKDESAIRK--AAIKYKVPYITTLAGAYNTVKGI-------------AAARNGHGA--VKSLQEYHASIEEV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
111 UniRef50_A1HRA8 Sigma54 specific transcript... 103 2e-20 1 28.3% 5:149 28:167 ----IRIERGLLSAG-----VRIARKLVEDGVeiISRGGTASAIKDAGLPVTIVepITGF----DVIRTVEQAKQYGTRIGVVAFPSMVMGIDCLGPILGVDIRQYIITDEFQAESRVLQAFREGAdvGGVITGKSAQKHHQPYVLIKS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
112 UniRef50_A8V5Q7 Carbamoyl-phosphate synthas... 102 4e-20 1 20.7% 8:128 157:278 -------GNVFISVADKDkvLEIAKKLKSLGFIILATKGTFKFLTENNVEAQLVSKleERPNIVDKIRN-------GEVQLIINTPSGKRERSDAYYIRRAAvhKVPYFTTIRGAYAAAVAieKGIDV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
113 UniRef50_Q3APN7 Carbamoyl-phosphate synthas... 100 1e-19 1 19.8% 2:122 474:594 -NMQLPlgAVFISVNDQDkmLAIARSLYDMDFDLVATAGTWQFLTDNGIECKKVYKveGRPNIFDSIK-------HGKVDFVINTPRGEKALHDEEAIGAavLSNVPFVTTIEAAEASVQAI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
114 UniRef50_A2BWE6 Carbamoyl-phosphate synthas... 99 2e-19 1 23.7% 10:127 972:1090 ---------AFLSTNdkDKLEEIARELIVLGFKLIATKGTASYLLNLGIEVDEVLKveGRPNIEDLIRSGL-------IQLVINTPIGSQAFHDDAYLRRAALEyiPTFTTIPGAKAALQAiiNKID------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
115 UniRef50_C5JG53 Bifunctional pyrimidine bio... 99 2e-19 1 19.9% 4:164 1674:1856 ---KLPKKNVLFSikEKVEMLPSIRKLHALGYNLFATAGTADYLKEHGLPVKYLEVLAGEEEDLKSEYSLTQHLANNLIDLYINLPSSNRFRRPANYmrMAVDYQTPLVTNVKNAKILIEAIARhidvTIPGLINVAA----FVPGLANPddFQVVTKASIANG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
116 UniRef50_A2QRW1 Contig An08c0170, complete ... 100 3e-19 1 21.3% 4:125 1399:1530 ---RLPKRNVLFSikEKMEMLPSIRKLHQIGFNLFATSGTADFLKENGVPVKYLEILPGEEEDIKSEYSLTQHLANNLIDLYINLPSNNRFRRPANYmrMAVDYQTPLVTNVKNAKILIEAIARH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
117 UniRef50_A5B1A5 DNA-directed RNA polymerase... 98 8e-19 1 39.6% 8:103 22:119 -------KQALISLSEKNDLAFLGNSLQILGYRIVSFGGTTLALENAWVSTTKVEQLTCFPKILDGHVKTLHPNIQGGILPRRDQKHhaLNEHGIGTFDVVVI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
118 UniRef50_A7HVJ4 Carbamoyl-phosphate synthas... 97 1e-18 1 28.8% 3:127 945:1063 --TKVPVttVFVSvsDKAKIVAPAKKLLDMGFKLVATGGTQRYLAEQGIEVGTINKveGRPHIVDAIKNGEVALVFNT------TEGAQALSDSMSLRRSALMMKVPYYTTVAGARA----AVEGID------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
119 UniRef50_C0NSX2 Carbamoyl-phosphate synthas... 96 2e-18 1 21.3% 4:125 1626:1757 ---KLPNKNVLFSikEKVEMLPSIRKLHALGYNLFATAGTADYLKEHGLPVKYLDVLAGEEEDLKSEYSLTQHLANNLIDLYINLPSSNRFRRPANYmrMAVDYQTPLVTNVKNAKLLIEAIARH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
120 UniRef50_O93937 Aspartate carbamoyltransfer... 96 3e-18 1 22.1% 4:125 1397:1528 ---KLPKRNILLSikEKMEMLPSIIKLRDVGFELFATSGTADFLKENGVPVKYLEILPGEDEDIKSEYSLTQHLANNLIDLYINLPSSNRFRRPANYmrMAVDYQTPLVTNVKNAKILIEAIARH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
121 UniRef50_B9L7I5 Carbamoyl-phosphate synthas... 95 7e-18 1 21.9% 8:112 960:1061 -------GKVFISLtdKEFAPALAKALKNHGFEIVATSGTYKVISEAGIECERVLKieGRPNIVDMIKNE-------EIALVINTSDNKASKDDAKIIRREVLNqiPYFTTI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
122 UniRef50_Q8YQL2 Carbamoyl-phosphate synthas... 95 8e-18 1 19.8% 3:123 967:1085 --ERLPLttVFVSMSdkSAAVPVVREFIDLGFKVMATFGTRRVLLENGLNVELVLKleGRPHVIDAIKNQ-------KIQLIINTPSGEEAQTDARLIRRTGLAyiPIITTIAGAKATVAAIR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
123 UniRef50_B0U8L9 Carbamoyl-phosphate synthas... 94 1e-17 1 23.3% 8:123 1027:1139 -------GTVFVSvaDKARILPAVRMLAEIGFAILATGGTQRFLAENGVAATRINKveGRPHVVDAIKN-------GEIHLVFNTTEGAGALSDSRSLRRAalHKVPYYTTLAGAMAAAEGIR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
124 UniRef50_C3XFR9 Carbamoyl-phosphate synthas... 94 1e-17 1 19.8% 3:118 1076:1188 --NPLPKkkIFISlsDKKHAAGLAKTLQEIGFEIVATLGTHKILSEAGIEAKAVLKveGRPHINDMIANH-------EIDMVINTSSNKAQP-DARLIREAVLRaiPYFTTISGAKSA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
125 UniRef50_C0A8Y6 Carbamoyl-phosphate synthas... 94 1e-17 1 22.6% 8:122 999:1110 -------GNVFLSvsDKKRAVDLARQLIKLGFTIYSTSGTAQHLADCGVPVTRLAKieGRPNTIDMIKNN-------QIQLVINTPSGMIPRQDENKIRSAaaHSVCIMTTITGAFAALSGI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
126 UniRef50_UPI000197805F carbamoyl phosphate synthas... 94 2e-17 1 19.1% 10:124 1103:1214 ---------VFLSLadKKEGVALANDFIELGFSICATEGTYKILCENGIEASHILKveGRPNIIDRMMNN-------QIALAINTSDNLSNKDDTHLIRTQIisSIPYFTTLAAARVAIEAIRD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
127 UniRef50_C9LZI0 Carbamoyl-phosphate synthas... 92 4e-17 1 21.2% 8:125 76:193 -------GNVLLTirDKEKILPIAKRFARIGYRIFATKGTANFLKKNDLHVELVTKVHEDEQAYDNILNELR---DGKIDLVINTMGHDIEKNSDGFiqMAIQQNVPLLTALDTADALLKS-LEN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
128 UniRef50_Q9KHE9 Carbamoyl phosphate synthet... 91 1e-16 1 20.5% 12:123 2:108 -----------MSDRDKSAAVPVVREFIDLGFKVMATFGTRRVLLENGLNVELVLKleGRPHVIDAIKNQ-------KIQLIINTPSGEEAQTDARLIRRTGLAyiPIITTIAGAKATVAAIR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
129 UniRef50_B8GEA3 Carbamoyl-phosphate synthas... 91 1e-16 1 21.4% 2:113 917:1026 -DNELPIenVFISVsqKEEVRRIAAQLRDLGLTLFGTKGTVETLMQAGIEANLVRKveGSPNVIDMVRK-------GEIRLIINTPVDKQSRLDHYQIMRAAVDyiPYITTLQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
130 UniRef50_C0R503 Carbamoyl-phosphate synthas... 90 2e-16 1 18.6% 10:122 1023:1132 ---------ALVSVKdkEYILPVVRMLKELSFEIYATKGTALYLNNNGIAAKAVNKveGRPHIVDMLKD-------GKINLVINTSKGVKSVSDSKDIRraILQNIAYSTTASGSKALVLAI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
131 UniRef50_Q9CKV0 Carbamoyl-phosphate synthas... 90 2e-16 1 23.3% 2:117 930:1044 -NERIPKtkVFLSvaDKPRLLPIARQLQESGYGLCATLGTAKFLREHGVAVQIINKveGRPNIVDAIKNG---EIAMVINTVSGLAETVTDGHAIR--RSALQQKVFLQTTLAGAEA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
132 UniRef50_Q9ZKT2 Carbamoyl-phosphate synthas... 89 4e-16 1 20.7% 5:125 952:1071 ----NPIKniFVSIKDkeEACVLMKRLVELGFELCTTEGTHKALEKAGVKSLKVLKieGRPNIMDLMMN-------GEISMAINTSDHK-SQDDAKLIRavLKNHVSYFTTLSAIEVLLLALEES--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
133 UniRef50_B2A170 Carbamoyl-phosphate synthas... 89 5e-16 1 19.2% 10:129 973:1089 ---------VLVTVAdkEAVRPLVERFQKLGLKIFATSGTAEFLRNQGIDVEQVPKidESPNIIDLIRE-------GQINYVIntIGKEPARDGFKIRRAAVENGIPCLTSLDTASALL-TAMESLDRG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
134 UniRef50_O50236 Carbamoyl-phosphate synthas... 88 8e-16 1 31.7% 11:111 982:1079 ----------FISvsDKAQIVEPIKALTDLGIKLVATDGTARYLQSKGVPVERVNKveGRPHIVDLIKD-------GAISLVVNTTEGWQSLQDSASIrsVVLAPVPYFTT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
135 UniRef50_Q2FLD9 Carbamoyl-phosphate synthas... 87 2e-15 1 23.4% 3:113 920:1028 --NRLPkgNVFISVTdkDQILQVAKTFTENGLSIYATSGTVEFFAERGITANLVRKieGSPNVLDMLR-------AGEISLIINNFADKQSRHDHQQIMRVAVDytPYITTLQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
136 UniRef50_A9QP20 Carbamoyl phosphate synthet... 86 2e-15 1 21.6% 9:124 992:1105 --------YITVKNADKHDVIPLAQELEEMGFTIYATRGTAHVLRDsgVDVQTCYRITetPDALDLMRQG---KIHLILNTPRNTGGAVLDGNMMR--RLAVELNIPFVTTMAGARMEVQAIAE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
137 UniRef50_Q9HK17 Carbamoyl-phosphate synthas... 86 4e-15 1 19.8% 2:122 911:1030 -SLQRSISSVLITVRdkPRIVDIARILLEKGVKLYATAGTSKFLADHGIPTETLYRVRDRREP-----RILDMISSGSIDMVINTTEMTAGarDGFKIRRICImgIPLIMNINLARAYAEAL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
138 UniRef50_Q17XX3 Carbamoyl-phosphate synthas... 86 4e-15 1 19.8% 5:125 1000:1119 ----NPIKniFVSIKDkeEACVLMKRLVQLGFELCATEGTHKALEKARVKSLKVLKieGRPNIMDLMMN-------GEISMAINTSDHK-SQDDAKLIRavLKNHVSYFTTLSAIEVLLLALEES--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
139 UniRef50_UPI0001B44E07 carbamoyl phosphate synthas... 85 5e-15 1 19.4% 1:124 78:193 MSDERGVVLATVNNHDKDEFIEIAXDMKELGYTFVATEGTAKSLRENGIEADIVNRVEerPNILDAIRNK-------QVDIVINTpkGNDSTRDGFKIRRTAIE---FSTEIMTSLDTLKALVE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
140 UniRef50_Q03WW7 Carbamoyl-phosphate synthas... 84 1e-14 1 20.4% 8:120 936:1046 -------GNVLFTVAdkEEALELAKRFNDLGFALFATAGTGAYLSDNDLPVEVLDKISESDNNAVAALR--QQKVQVVINTTQADDRAESDGRLIR--NAAIENAVPLFTALDTVSAFLE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
141 UniRef50_Q8UDE9 Carbamoyl-phosphate synthas... 84 1e-14 1 20.0% 8:112 1033:1134 -------GTVFVSVRdkEGVLSAIRILVESGFKVLATGGTQRFLAEQGINAEKINKveGRPHIEDAIRN-------RQVQLVINTTDSNKAISDSKSLRRalMQKVPYYTTM---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
142 UniRef50_A8JIR0 Carbamoyl phosphate synthas... 82 4e-14 1 23.2% 3:114 927:1037 --QKLPKtkVFVSMADkpDIIEIARNLGNLGFGLVATTGTALALRNAGVPCEQVFKieGRPNPADLMRNGE------VTLMMMTSGGDEADLRDGKELRRLALQliPTVTTVAG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
143 UniRef50_B7G8W8 Predicted protein n=7 Tax=c... 81 1e-13 1 22.2% 4:129 1365:1492 ---PNKNRTILLSIASEEYRREFAEalHRLGYKLFGTPGTAAYYQDngIEIKSVSK--PDAETDDAPGTALHEIKNGKIDLVINVSEGATRREEITsiRRAVVDfvSLVTDVKCAI----KLAECFDRG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
144 UniRef50_Q0TM79 Carbamoyl-phosphate synthas... 80 2e-13 1 23.4% 10:103 944:1032 ---------ATIKKHDKKEFMELAKDLDKLGYNFIATTGTAKELREAGIDAKEVRRieESPNIMDLIKNK-------EIDLVVNTpkANDSKRDGFHIRRAAI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
145 UniRef50_C0AZ23 Putative uncharacterized pr... 80 2e-13 1 23.1% 2:118 27:140 -STMKKKGRALLSVrdKKRVVDLATKLLKSGFELDATHGTAIVLGEAGINPRLVNKveGRPHIEDRIKN-------GEYDYIVNTTSGRQAIEDSKIIRRSALRyvHYDTTLNGGFAT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
146 UniRef50_B9KXM5 Carbamoyl-phosphate synthas... 80 2e-13 1 21.9% 10:123 944:1056 ---------VLLSLAdkSAGVELARGLLALGHPLVATEGTARYLRAHGVPV----ELT-VAHIGHGHPDVLEVILERKVRGVINTPGRDEgiQDGFLIRRAAvrGIPCLTSLDTARALVRALL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
147 UniRef50_A6LPD9 Carbamoyl-phosphate synthas... 80 3e-13 1 19.8% 2:127 936:1061 -SKEKGKILATINKHDKAEFLPIAKDLASVGYKFIATSGTCALLKEAGIEVEEIRKieEEPNILDIVKN-------REVDLVVNTpkGNDSKRDGFLIRRAAvnliTALDTlaIADVELEKFDENKD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
148 UniRef50_UPI0001B41F6C carbamoyl phosphate synthas... 79 4e-13 1 19.6% 8:119 90:199 -------GTVLLTVAdkEEAVELAKRFNRIGFTIMATKGTASTLEEASIPVSQVKKIGENQETLIDYIRNGQVTLVVNTLTTGKRPE-----RDGFQIRRevENGIPVCTSLDTAEAIL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
149 UniRef50_A8F453 Carbamoyl-phosphate synthas... 78 6e-13 1 21.1% 10:123 954:1079 ---------VTVNDRDKREIVPLVSYLYDLGFEVFATAGTGKILRSMGIAVKNVFKveGKPDVVDLIRQGknRKTSAEINREAENSFADDERTAGYKIRTAAIqkVPCITTIEAFRAEVSAIR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
150 UniRef50_A6CPS0 Carbamoyl-phosphate synthas... 77 2e-12 1 21.2% 10:146 35:167 ---------VLLTVADKdeAIGLAKRFVNIGYQILATKGTADVLRTADIPVKEVDKI------GSEGPTLLDVIQSGETQLVINttKGKQPQRDGFRIRRevENGIPCLTSLDTAEAILKVF-ESMTFSAEAME-GAEKNQEAVLL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
151 UniRef50_C9KKE3 Carbamoyl-phosphate synthas... 76 3e-12 1 19.6% 7:103 927:1020 ------KGCILFTVADkeEMKQLAKAFSELGFEICATEGTAKAIQSMGIDAEVVGKVHERSSDIIQMIKN------GKINMVINttQGKHSAKDGFKIRRATV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
152 UniRef50_D1CBW2 Carbamoyl-phosphate synthas... 76 3e-12 1 14.2% 3:122 953:1071 --NPPPGGSVLMSIAdkPEALPLAAALVDMGYALVCTEGTSTFFEDNGIRVNQVVHKIgrPDITDIIRR-------RQVSLVINTPSRSGrrDGFEIRRAAAESGIPCLTSLDTAKSLVKAL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
153 UniRef50_C1A4I5 Carbamoyl-phosphate synthas... 76 4e-12 1 19.6% 2:108 936:1040 -DNALPRetVFFTVSdkPTAASLAGKFHSIGFSIMATSGTAAFFREQGIPVTSVLKveGRPHGVDKILN-------GEVQLLVNTPLGkaQVDDEKLRQAAIANRLPY-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
154 UniRef50_Q1RKZ5 IP15551p (Fragment) n=1 Tax... 74 1e-11 1 18.9% 4:125 89:224 ---QIPKNAVLLSikHKMELLPSIRDLAKMGYKLYASMGTGDFYAEHGVNVESvdKTT--PDDINGELRHleFLANKQFDLVINLpvSSFMTHGYRTRRLAVDYSIPLVTDVKCTKLLVESMRMN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
155 UniRef50_P05990 Dihydroorotase n=643 Tax=ce... 74 1e-11 1 18.9% 4:125 1323:1458 ---QIPKNAVLLSikHKMELLPSIRDLAKMGYKLYASMGTGDFYAEHGVNVESvdKTT--PDDINGELRHleFLANKQFDLVINLpvSSFMTHGYRTRRLAVDYSIPLVTDVKCTKLLVESMRMN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
156 UniRef50_UPI0001C31DA7 carbamoyl-phosphate synthas... 72 7e-11 1 17.1% 8:112 900:1001 -------GTVFITVTdkPAAAGVAMALHGLGFRIVATAGTAQAIKRMGIPVEALEKI------GSGSPNVLELIERGEVKLVVNTPVGTGARIDGWEIRSAAIAaiPCITTM---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
157 UniRef50_Q4SZL4 Chromosome 14 SCAF11586, wh... 70 2e-10 1 20.0% 4:123 1191:1325 ---KIPKKNILLSikNKSELLPTVQALESLGYDLYASLGTADFYTEHGVKVTAVD--WPFEEDDNGcrSIMNYLEENHFDLVVNLSMRNSGGrgYRTRRMAVDYSVPLIIDIKCTKLFVQALR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
158 UniRef50_B1YIR9 Carbamoyl-phosphate synthas... 70 2e-10 1 19.1% 8:122 936:1048 -------GRVLLTVAdkQEMLDLAKRFTALGFTLLATAGTASVLEEHGLRVQVVGKL------GSEQGSMLEWIEKAEVEYVINTMSRDSQVTKDGFirAAAENNVVCLTSLDTAEALLRVI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
159 UniRef50_UPI000194C4F6 PREDICTED: similar to carba... 69 4e-10 1 16.0% 4:122 1042:1176 ---KIPKKNILlsYKNKSELLPTVRTLENLGYNLYASLGTADFYTEHGIKVKAVD--WHFEEADSSerSILDYLAENHFEMVINLSMRNSGGrgYRTRRLAVDYSVPLIIDIKCTKLFVEAL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
160 UniRef50_A5B3D8 DNA-directed RNA polymerase... 69 5e-10 1 54.8% 63:124 1:64 --------------------------------------------------------------MLDGHVKTLHPNIHGGILARRDQKHhaLNEHGIGTFDVVVVNLYPFYDKVSLGGIEFEDEIE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
161 UniRef50_C8PAM0 Carbamoyl-phosphate synthas... 69 5e-10 1 21.0% 8:126 933:1041 -------GTVFISvsDKKSAISVAARFHKLGFQLLATEGTANILAEEGITTSIVEKL------QTGNNSLLEKIAQHKINLVIntNLSDSASHDAIMIKDQALnhIPVFSSIQSA--------ENI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
162 UniRef50_P27708 Dihydroorotase n=533 Tax=ce... 69 6e-10 1 17.6% 4:122 1309:1440 ---KIPKKNILlsYKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAVD--WHFEEAVDGerSILEQLAEKNFELVINLSMRGAGGrgYRTRRLAADFSVPLIIDIKCTKLFVEAL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
163 UniRef50_B8DTW3 Carbamoyl-phosphate synthas... 68 8e-10 1 19.1% 8:96 970:1072 -------GNVFISvtDKRQLPLFAVRLVELGFEIWATEGTASVLRRYGIESKIVDKIHSrpeaGSVGKNVVELIEEGQIDLILNTPNSRGSRSDGY-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
164 UniRef50_D1Y1S0 Carbamoyl-phosphate synthas... 66 3e-09 1 21.1% 10:137 952:1077 ---------VLISvrDKPEIVELARRLASLGCRLYTTGGTAEYLKSRGIRSASVGKISQ------GNRDIPYLLDQGRVQYVLSTSSPDSSERADAQVLraIERRAACMTSLDTARALVDCMVSGYDEGNVELVDMA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
165 UniRef50_Q1GA90 Carbamoyl-phosphate synthas... 65 6e-09 1 18.6% 8:120 941:1051 -------GTIFFSVSdkQEVANLAKRFARLGFKITATEGTANILAEAGITTGVIAKI------QEGSRNLLERIQTHRIVMVVnnLSDSAVEDSIKIKDQALNTHIPVFSSLETVQLILD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
166 UniRef50_B0E550 Predicted protein n=1 Tax=L... 65 8e-09 1 33.3% 453:503 72:122 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CQRCSFEGRGKEGVELDGVARSSDAFFPLPDNMHRARKSGIRCLAAPSGSV--------------------------
167 UniRef50_A5D508 Carbamoyl-phosphate synthas... 64 2e-08 1 21.8% 8:117 938:1040 -------GRVVFSVAdkAEAVSIAGEYAALGYTLHATPGTARALEKAGLEVEVVEITDPVPLIRSGTV---------GLIINTPTRGKVPGRPGFLLRRTAAEYRVPCLTSLDTARA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
168 UniRef50_D2LJN2 MGS domain protein n=1 Tax=... 63 2e-08 1 16.7% 4:123 19:140 ---RKSRKKVLISAgdKARMLPAIKQFLSLEVDVFATPGTHRFLTRHGIDTVEIHKItgRAPNIRTFLNENRFDLVINVLTGDNDYD---ESSDAKLIRKLCinGIPLITDCDVGIETLQQIV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
169 UniRef50_C6Q1M4 MGS domain protein n=1 Tax=... 60 2e-07 1 13.1% 16:122 43:140 ---------------DKKEGIDIIKDYQKLGFKFYASEGTGNYLKGNAIDCTIidQVSEF-------------IVDGKIKMLINTPTrnPESEGFKLRRKAAEYRVPVFTCIDTAKIFLTAI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
170 UniRef50_B4R614 GD17297 n=1 Tax=Drosophila ... 57 1e-06 1 29.2% 4:51 1176:1226 ---QIPKNAVLLSikHKMELLPSIRDLAKMGYKLYASMGTGDFYAEHGVNV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
171 UniRef50_B7PNL6 Carbamoyl-phosphate synthas... 55 5e-06 1 24.5% 5:53 260:311 ----IPKKNIFLSikHKAEFLPSVRTLEKMGYKLYGSLGTSDFYMEHGIKIEA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
172 UniRef50_UPI0000382898 COG0138: AICAR transformyla... 48 0.001 1 62.5% 7:38 1:32 ------MTRALLSVSDKTGLTDFAAALIGQGVELVSTA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
173 UniRef50_A9V282 Predicted protein n=2 Tax=c... 68 9e-10 1 16.0% 4:122 1084:1208 ---PRPQGNVLLSiydkLEFLDSTRRLQQLGFKLFGSMGTADFYLSHGVEIKPVDWLADT-EDIESIKDNL---LDGHYDMVINLPMRNKYRRPASYmrMAVESKVPLITNIKCAKLFIAAL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
174 UniRef50_C6XKE0 MGS domain protein n=1 Tax=... 56 3e-06 1 16.4% 1:165 19:176 MLSKGRERALLISAgdKQFLLESCRNMADIGVNIFATPGTQRLFEAQNIKSS----------PAHKISSGTQPNinGEIDFVINILTGEQDYddAKQIrlAIKHGIPLITDREVARETIATVITNIEQGTYDWKRRSAQR---------PWDLEAKFRELVEERG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
175 UniRef50_P31327 Carbamoyl-phosphate synthas... 56 3e-06 1 16.0% 4:122 1356:1477 ---KIPQKGILIGisFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVA--WPSQEGQNPSLSSIRKLidGSIDLVINLPNNNTKfhDNYVIRRTAVDsiPLLTNFQVTKLFAEAV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
176 UniRef50_A9A4K3 Carbamoyl-phosphate synthas... 55 8e-06 1 13.9% 8:122 940:1060 -------GTAVVTVgnKEKLLSSIAKLKQLGFKIMATEHTAEFFEEkgIEIikISEPERLPNIADMLYE-------RKIDFIINIPSTSTIedDEYQIRRKAIEliPVLTTIELADSFVKTL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
177 UniRef50_C4QQ90 Aspartate carbamoyltransfer... 52 5e-05 1 23.1% 4:55 406:460 ---PKPGDNVFLSirHKLEMLPSVKQLHQLGYKLYGSCGTADFYQTQGISIIPVE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
178 UniRef50_UPI00017430FF carbamoyl phosphate synthas... 51 1e-04 1 17.3% 29:126 2:97 ----------------------------DLGYHIMATKGTAKYFEDKGLHVETVGKI---DEEGIYEHDVLGLIYKGLVDMVINtaKKKTARNDGFKIRRAASEqiACLTSLDTTDALLK-VLESI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
179 UniRef50_B3LBP4 Carbamoyl phosphate synthet... 51 1e-04 1 12.5% 3:122 2010:2143 --MKLPKKSILISIKnkLAFEEPFQLLFLMGFTIYATEGTYDFYSkeSFNVTKGSKFHQrkSSENLMPNITDLIMNHKVEMVINITdkTKVSSNGYKIRRLASDfvPLITNMKLSSLFIDSL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
180 UniRef50_Q8IEN3 Carbamoyl phosphate synthet... 50 2e-04 1 12.5% 3:122 2216:2349 --MKLPKKSILISIKnkLAFEEPFQLLFLMGFTIYATEGTYDFYSkeSFNVNKGSKFHQrkNAENISPNTTDLIMNHKVEMVINITdkTKVSSNGYKIRRLASDfvPLITNMKLCSLFIDSL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
181 UniRef50_A7T4N0 Predicted protein (Fragment... 50 2e-04 1 16.1% 17:128 789:891 ----------------KNELLPSVHTLRNLGYSLYASVGTADFYTEHGIT------------------NMIDLFINLPLRSNPGKKVSSFMTRGYQTRRMAIDYSVPLITDVKCAKLFVEALKrnIDI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
182 UniRef50_B2KDJ0 Carbamoyl-phosphate synthas... 49 5e-04 1 28.8% 4:69 971:1038 ---KMPKKGILLStkDKIKFMEVIDNVYKFGLPVYATLGTANYLKEHGYDAIPVM-YHHDPKPVDVIKQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
183 UniRef50_Q1NYU0 Carbamoyl-phosphate synthas... 48 0.001 1 10.7% 4:124 43:152 ---NIPKKNIFisIKNRKIMLNYIKLLIINNYIIFSKNGTYNFFIENNILCKNIDDT----NLIDNLKK---------IDLIINITYKNNKND--YLIRRAAIDfiPLLTNICLAKVFIISFCE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
184 UniRef50_B6KSM2 Carbamoyl phosphate synthet... 48 0.001 1 23.3% 4:46 1506:1551 ---PLEKRTILIslWSKMELEPYFKILLDLGFTIYATEGTYRFLMN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
185 UniRef50_C1TLQ6 Carbamoyl-phosphate synthas... 46 0.004 1 27.8% 6:59 931:986 -----RKGRVLFSVDdkAEACAIAALFESKGWEVEGTPGTAYFFSRWGVSCRSVVKKDG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
186 UniRef50_UPI0001BCC751 carbamoyl phosphate synthas... 45 0.007 1 13.3% 43:125 12:89 ------------------------------------------ILKDAAIECEMVYKieGRPNIEDKLKN-------GEVSLAVNTSDNKSSSSDAHKIRQAVLRfiPYFTNMNAALVAAKSISAN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
187 UniRef50_C5KGZ1 Putative uncharacterized pr... 44 0.019 1 21.0% 5:104 1408:1511 ----LPTKTILVSIgqKEEFLPWASILISLGYHLFATRSTYQVMKDKLNPstLVYKPYARREPN---VKTL--IQNGKIDmvIPSSADSCAITEGFEMRRLAVD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
consensus/100% .................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................
consensus/90% ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................
consensus/80% .......hhhoh.pK.th...ht.h.t.shplhuo.uT.thh.t.sh.h..h..............p.........h..................ht.hh...........................................................................................................................................................................................................................................................................................................................................................................................................................................
consensus/70% .....thhlSl.cKtthh.hsptL.phuhplhuotGThphltptGl.s..ltphtt..p.hthhhp.......ttl.h.hs..ttt.tt.th..hchhh.p.hsh.pth.........h........................................................................... ................................................................................................................................................................................................................................................................................................................................
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