Processing 1 helix: Transmembrane helix 1 from 52 (in) to 82 (out) : 2845.28 Score = 2.778202 Processing 1 helix: Transmembrane helix 1 from 52 (out) to 82 (in) : 2851.82 Score = 2.918897 Processing 6 helices: Transmembrane helix 1 from 8 (in) to 23 (out) : 1128.05 Transmembrane helix 2 from 27 (out) to 42 (in) : -676.284 Transmembrane helix 3 from 46 (in) to 61 (out) : 1952.76 Transmembrane helix 4 from 70 (out) to 85 (in) : 2259.26 Transmembrane helix 5 from 89 (in) to 104 (out) : 223.624 Transmembrane helix 6 from 108 (out) to 123 (in) : 972.235 Score = -100000.000000 Processing 5 helices: Transmembrane helix 1 from 8 (out) to 25 (in) : 1206.16 Transmembrane helix 2 from 45 (in) to 60 (out) : 1965.95 Transmembrane helix 3 from 70 (out) to 85 (in) : 2259.26 Transmembrane helix 4 from 89 (in) to 104 (out) : 223.624 Transmembrane helix 5 from 108 (out) to 123 (in) : 972.235 Score = 6.630157 Processing 4 helices: Transmembrane helix 1 from 8 (in) to 25 (out) : 1188.64 Transmembrane helix 2 from 45 (out) to 60 (in) : 1974.25 Transmembrane helix 3 from 70 (in) to 92 (out) : 2602.5 Transmembrane helix 4 from 101 (out) to 118 (in) : 1423.16 Score = 7.226178 Processing 3 helices: Transmembrane helix 1 from 45 (out) to 60 (in) : 1974.25 Transmembrane helix 2 from 70 (in) to 92 (out) : 2602.5 Transmembrane helix 3 from 101 (out) to 118 (in) : 1423.16 Score = 6.064877 Processing 2 helices: Transmembrane helix 1 from 48 (in) to 78 (out) : 2657.95 Transmembrane helix 2 from 82 (out) to 112 (in) : 2032.71 Score = 4.682846 Processing 6 helices: Transmembrane helix 1 from 8 (out) to 23 (in) : 1144.95 Transmembrane helix 2 from 27 (in) to 42 (out) : -673.116 Transmembrane helix 3 from 46 (out) to 61 (in) : 1960.24 Transmembrane helix 4 from 70 (in) to 85 (out) : 2249.34 Transmembrane helix 5 from 89 (out) to 104 (in) : 222.976 Transmembrane helix 6 from 108 (in) to 123 (out) : 973.665 Score = -100000.000000 Processing 5 helices: Transmembrane helix 1 from 8 (in) to 25 (out) : 1188.64 Transmembrane helix 2 from 45 (out) to 60 (in) : 1974.25 Transmembrane helix 3 from 70 (in) to 85 (out) : 2249.34 Transmembrane helix 4 from 89 (out) to 104 (in) : 222.976 Transmembrane helix 5 from 108 (in) to 123 (out) : 973.665 Score = 6.605943 Processing 4 helices: Transmembrane helix 1 from 8 (out) to 25 (in) : 1206.16 Transmembrane helix 2 from 45 (in) to 60 (out) : 1965.95 Transmembrane helix 3 from 70 (out) to 92 (in) : 2601.7 Transmembrane helix 4 from 101 (in) to 118 (out) : 1398.43 Score = 7.134623 Processing 3 helices: Transmembrane helix 1 from 45 (in) to 60 (out) : 1965.95 Transmembrane helix 2 from 70 (out) to 92 (in) : 2601.7 Transmembrane helix 3 from 101 (in) to 118 (out) : 1398.43 Score = 5.901124 Processing 2 helices: Transmembrane helix 1 from 48 (out) to 78 (in) : 2661.55 Transmembrane helix 2 from 82 (in) to 112 (out) : 2006.69 Score = 4.676054 Summary of topology analysis: 1 helix (+) : Score = 2.7782 1 helix (-) : Score = 2.9189 2 helices (+) : Score = 4.68285 2 helices (-) : Score = 4.67605 3 helices (+) : Score = 5.90112 3 helices (-) : Score = 6.06488 4 helices (+) : Score = 7.22618 4 helices (-) : Score = 7.13462 5 helices (+) : Score = 6.60594 5 helices (-) : Score = 6.63016 6 helices (+) : Score = -100000 6 helices (-) : Score = -100000 Results: Signal peptide: Not detected. Signal score: 0.926 Topology: 8-25,45-60,70-92,101-118 Re-entrant helices: Not detected. Helix count: 4 N-terminal: in Score: 7.22618