Secondary structure and disorder prediction

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Sequence		M	K	L	R	K	I	L	K	S	M	F	N	N	Y	C	K	T	F	K	D	V	P	P	G	N	M	F	R
Secondary structure
SS confidence
Disorder		?	?																				?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2juc chain A Region: 8 - 15 Aligned: 8 Modelled: 8 Confidence: 10.6% Identity: 38% PDB header:unknown function Chain: A: PDB Molecule:pre-mrna-splicing factor urn1; PDBTitle: urn1 ff domain yeast Phyre2 PDB 1rqp chain A domain 1 Region: 14 - 27 Aligned: 14 Modelled: 14 Confidence: 10.1% Identity: 36% Fold: Bacterial fluorinating enzyme, C-terminal domain Superfamily: Bacterial fluorinating enzyme, C-terminal domain Family: Bacterial fluorinating enzyme, C-terminal domain Phyre2 PDB 2q6o chain B Region: 14 - 27 Aligned: 14 Modelled: 14 Confidence: 7.5% Identity: 43% PDB header:biosynthetic protein Chain: B: PDB Molecule:hypothetical protein; PDBTitle: sall-y70t with sam and cl Phyre2 PDB 2dod chain A domain 1 Region: 8 - 17 Aligned: 10 Modelled: 10 Confidence: 7.5% Identity: 50% Fold: Another 3-helical bundle Superfamily: FF domain Family: FF domain Phyre2 PDB 1wu8 chain B Region: 14 - 27 Aligned: 14 Modelled: 14 Confidence: 6.5% Identity: 29% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:hypothetical protein ph0463; PDBTitle: crystal structure of project ph0463 from pyrococcus horikoshii ot3 Phyre2 PDB 2zbv chain C Region: 14 - 27 Aligned: 14 Modelled: 14 Confidence: 6.4% Identity: 36% PDB header:structural genomics, unknown function Chain: C: PDB Molecule:uncharacterized conserved protein; PDBTitle: crystal structure of uncharacterized conserved protein from thermotoga2 maritima Phyre2 PDB 2w2d chain D Region: 5 - 16 Aligned: 12 Modelled: 12 Confidence: 5.9% Identity: 42% PDB header:hydrolase Chain: D: PDB Molecule:botulinum neurotoxin a heavy chain; PDBTitle: crystal structure of a catalytically active, non-toxic2 endopeptidase derivative of clostridium botulinum toxin a Phyre2 PDB 3pyw chain A Region: 16 - 25 Aligned: 10 Modelled: 10 Confidence: 5.8% Identity: 60% PDB header:structural protein Chain: A: PDB Molecule:s-layer protein sap; PDBTitle: the structure of the slh domain from b. anthracis surface array2 protein at 1.8a Phyre2 PDB 2odm chain A Region: 1 - 27 Aligned: 27 Modelled: 25 Confidence: 5.6% Identity: 19% PDB header:unknown function Chain: A: PDB Molecule:upf0358 protein mw0995; PDBTitle: crystal structure of s. aureus ylan, an essential leucine rich protein2 involved in the control of cell shape Phyre2 PDB 1nov chain E Region: 2 - 12 Aligned: 11 Modelled: 11 Confidence: 5.2% Identity: 55% PDB header:virus Chain: E: PDB Molecule:nodamura virus coat proteins; PDBTitle: nodamura virus Phyre2 1 c2jucA_ 2 d1rqpa1 3 c2q6oB_ 4 d2doda1 5 c1wu8B_ 6 c2zbvC_ 7 c2w2dD_ 8 c3pywA_ 9 c2odmA_ 10 c1novE_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2jucA_ 10.6 38 PDB header:unknown function Chain: A: PDB Molecule:pre-mrna-splicing factor urn1; PDBTitle: urn1 ff domain yeast 2 d1rqpa1 10.1 36 Fold:Bacterial fluorinating enzyme, C-terminal domain Superfamily:Bacterial fluorinating enzyme, C-terminal domain Family:Bacterial fluorinating enzyme, C-terminal domain 3 c2q6oB_ 7.5 43 PDB header:biosynthetic protein Chain: B: PDB Molecule:hypothetical protein; PDBTitle: sall-y70t with sam and cl 4 d2doda1 7.5 50 Fold:Another 3-helical bundle Superfamily:FF domain Family:FF domain 5 c1wu8B_ 6.5 29 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:hypothetical protein ph0463; PDBTitle: crystal structure of project ph0463 from pyrococcus horikoshii ot3 6 c2zbvC_ 6.4 36 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:uncharacterized conserved protein; PDBTitle: crystal structure of uncharacterized conserved protein from thermotoga2 maritima 7 c2w2dD_ 5.9 42 PDB header:hydrolase Chain: D: PDB Molecule:botulinum neurotoxin a heavy chain; PDBTitle: crystal structure of a catalytically active, non-toxic2 endopeptidase derivative of clostridium botulinum toxin a 8 c3pywA_ 5.8 60 PDB header:structural protein Chain: A: PDB Molecule:s-layer protein sap; PDBTitle: the structure of the slh domain from b. anthracis surface array2 protein at 1.8a 9 c2odmA_ 5.6 19 PDB header:unknown function Chain: A: PDB Molecule:upf0358 protein mw0995; PDBTitle: crystal structure of s. aureus ylan, an essential leucine rich protein2 involved in the control of cell shape 10 c1novE_ 5.2 55 PDB header:virus Chain: E: PDB Molecule:nodamura virus coat proteins; PDBTitle: nodamura virus

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0