Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	R	A	F	I	M	V	L	D	S	F	G	I	G	A	T	E	D	A	E	R	F	G	D	V	G	A	D	T	L	G	H	I	A	E	A	C	A	K	G	E	A	D	N	G	R	K	G	P	L	N	L	P	N	L	T	R	L	G
Secondary structure
SS confidence
Disorder		?	?																		?		?	?																		?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	A	K	A	H	E	G	S	T	G	F	I	P	A	G	M	D	G	N	A	E	V	I	G	A	Y	A	W	A	H	E	M	S	S	G	K	D	T	P	S	G	H	W	E	I	A	G	V	P	V	L	F	E	W	G	Y	F	S	D	H
Secondary structure
SS confidence
Disorder							?		?	?	?	?	?	?	?	?	?	?	?	?	?					?						?			?	?		?	?	?										?	?	?	?	?	?	?	?			?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		E	N	S	F	P	Q	E	L	L	D	K	L	V	E	R	A	N	L	P	G	Y	L	G	N	C	H	S	S	G	T	V	I	L	D	Q	L	G	E	E	H	M	K	T	G	K	P	I	F	Y	T	S	A	D	S	V	F	Q	I	A	C
Secondary structure
SS confidence
Disorder																																													?	?									?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		H	E	E	T	F	G	L	D	K	L	Y	E	L	C	E	I	A	R	E	E	L	T	N	G	G	Y	N	I	G	R	V	I	A	R	P	F	I	G	D	K	A	G	N	F	Q	R	T	G	N	R	H	D	L	A	V	E	P	P	A	P
Secondary structure
SS confidence
Disorder																							?	?	?	?																						?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		T	V	L	Q	K	L	V	D	E	K	H	G	Q	V	V	S	V	G	K	I	A	D	I	Y	A	N	C	G	I	T	K	K	V	K	A	T	G	L	D	A	L	F	D	A	T	I	K	E	M	K	E	A	G	D	N	T	I	V	F	T
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		N	F	V	D	F	D	S	S	W	G	H	R	R	D	V	A	G	Y	A	A	G	L	E	L	F	D	R	R	L	P	E	L	M	S	L	L	R	D	D	D	I	L	I	L	T	A	D	H	G	C	D	P	T	W	T	G	T	D	H	T
Secondary structure
SS confidence
Disorder																																																									?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.
Sequence		R	E	H	I	P	V	L	V	Y	G	P	K	V	K	P	G	S	L	G	H	R	E	T	F	A	D	I	G	Q	T	L	A	K	Y	F	G	T	S	D	M	E	Y	G	K	A	M	F
Secondary structure
SS confidence
Disorder																	?	?	?	?	?																					?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3m8y chain C Region: 2 - 406 Aligned: 381 Modelled: 393 Confidence: 100.0% Identity: 46% PDB header:isomerase Chain: C: PDB Molecule:phosphopentomutase; PDBTitle: phosphopentomutase from bacillus cereus after glucose-1,6-bisphosphate2 activation Phyre2 PDB 2i09 chain A Region: 1 - 406 Aligned: 359 Modelled: 373 Confidence: 100.0% Identity: 38% PDB header:isomerase Chain: A: PDB Molecule:phosphopentomutase; PDBTitle: crystal structure of putative phosphopentomutase from streptococcus2 mutans Phyre2 PDB 2zkt chain B Region: 27 - 399 Aligned: 336 Modelled: 338 Confidence: 100.0% Identity: 16% PDB header:isomerase Chain: B: PDB Molecule:2,3-bisphosphoglycerate-independent phosphoglycerate PDBTitle: structure of ph0037 protein from pyrococcus horikoshii Phyre2 PDB 1hdh chain A Region: 26 - 406 Aligned: 361 Modelled: 380 Confidence: 100.0% Identity: 17% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Arylsulfatase Phyre2 PDB 1p49 chain A Region: 24 - 406 Aligned: 364 Modelled: 383 Confidence: 100.0% Identity: 14% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Arylsulfatase Phyre2 PDB 2qzu chain A Region: 20 - 406 Aligned: 347 Modelled: 352 Confidence: 100.0% Identity: 14% PDB header:hydrolase Chain: A: PDB Molecule:putative sulfatase yidj; PDBTitle: crystal structure of the putative sulfatase yidj from bacteroides2 fragilis. northeast structural genomics consortium target bfr123 Phyre2 PDB 1auk chain A Region: 26 - 406 Aligned: 312 Modelled: 319 Confidence: 100.0% Identity: 18% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Arylsulfatase Phyre2 PDB 3ed4 chain A Region: 27 - 407 Aligned: 327 Modelled: 327 Confidence: 100.0% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:arylsulfatase; PDBTitle: crystal structure of putative arylsulfatase from escherichia coli Phyre2 PDB 1fsu chain A Region: 25 - 407 Aligned: 310 Modelled: 314 Confidence: 100.0% Identity: 14% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Arylsulfatase Phyre2 PDB 3b5q chain B Region: 26 - 407 Aligned: 323 Modelled: 324 Confidence: 100.0% Identity: 10% PDB header:hydrolase Chain: B: PDB Molecule:putative sulfatase yidj; PDBTitle: crystal structure of a putative sulfatase (np_810509.1)2 from bacteroides thetaiotaomicron vpi-5482 at 2.40 a3 resolution Phyre2 PDB 2vqr chain A Region: 27 - 406 Aligned: 358 Modelled: 361 Confidence: 100.0% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:putative sulfatase; PDBTitle: crystal structure of a phosphonate monoester hydrolase2 from rhizobium leguminosarum: a new member of the3 alkaline phosphatase superfamily Phyre2 PDB 3lxq chain B Region: 26 - 407 Aligned: 274 Modelled: 275 Confidence: 100.0% Identity: 17% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein vp1736; PDBTitle: the crystal structure of a protein in the alkaline2 phosphatase superfamily from vibrio parahaemolyticus to3 1.95a Phyre2 PDB 2w8d chain B Region: 26 - 407 Aligned: 277 Modelled: 280 Confidence: 100.0% Identity: 14% PDB header:transferase Chain: B: PDB Molecule:processed glycerol phosphate lipoteichoic acid synthase 2; PDBTitle: distinct and essential morphogenic functions for wall- and2 lipo-teichoic acids in bacillus subtilis Phyre2 PDB 2w5t chain A Region: 25 - 407 Aligned: 280 Modelled: 280 Confidence: 100.0% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:processed glycerol phosphate lipoteichoic acid PDBTitle: structure-based mechanism of lipoteichoic acid synthesis by2 staphylococcus aureus ltas. Phyre2 PDB 2i09 chain A domain 1 Region: 1 - 407 Aligned: 275 Modelled: 284 Confidence: 100.0% Identity: 37% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: DeoB catalytic domain-like Phyre2 PDB 3q3q chain A Region: 19 - 406 Aligned: 355 Modelled: 356 Confidence: 100.0% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:alkaline phosphatase; PDBTitle: crystal structure of spap: an novel alkaline phosphatase from2 bacterium sphingomonas sp. strain bsar-1 Phyre2 PDB 1o98 chain A domain 2 Region: 26 - 406 Aligned: 263 Modelled: 267 Confidence: 100.0% Identity: 18% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, catalytic domain Phyre2 PDB 2gso chain B Region: 27 - 406 Aligned: 361 Modelled: 375 Confidence: 100.0% Identity: 12% PDB header:hydrolase Chain: B: PDB Molecule:phosphodiesterase-nucleotide pyrophosphatase; PDBTitle: structure of xac nucleotide2 pyrophosphatase/phosphodiesterase in complex with vanadate Phyre2 PDB 3szz chain A Region: 27 - 392 Aligned: 334 Modelled: 348 Confidence: 100.0% Identity: 13% PDB header:hydrolase Chain: A: PDB Molecule:phosphonoacetate hydrolase; PDBTitle: crystal structure of phosphonoacetate hydrolase from sinorhizobium2 meliloti 1021 in complex with acetate Phyre2 PDB 2xrg chain A Region: 23 - 404 Aligned: 248 Modelled: 253 Confidence: 100.0% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) in complex with the2 ha155 boronic acid inhibitor Phyre2 1 c3m8yC_ 2 c2i09A_ 3 c2zktB_ 4 d1hdha_ 5 d1p49a_ 6 c2qzuA_ 7 d1auka_ 8 c3ed4A_ 9 d1fsua_ 10 c3b5qB_ 11 c2vqrA_ 12 c3lxqB_ 13 c2w8dB_ 14 c2w5tA_ 15 d2i09a1 16 c3q3qA_ 17 d1o98a2 18 c2gsoB_ 19 c3szzA_ 20 c2xrgA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3m8yC_ 100.0 46 PDB header:isomerase Chain: C: PDB Molecule:phosphopentomutase; PDBTitle: phosphopentomutase from bacillus cereus after glucose-1,6-bisphosphate2 activation 2 c2i09A_ 100.0 38 PDB header:isomerase Chain: A: PDB Molecule:phosphopentomutase; PDBTitle: crystal structure of putative phosphopentomutase from streptococcus2 mutans 3 c2zktB_ 100.0 16 PDB header:isomerase Chain: B: PDB Molecule:2,3-bisphosphoglycerate-independent phosphoglycerate PDBTitle: structure of ph0037 protein from pyrococcus horikoshii 4 d1hdha_ 100.0 17 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 5 d1p49a_ 100.0 14 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 6 c2qzuA_ 100.0 14 PDB header:hydrolase Chain: A: PDB Molecule:putative sulfatase yidj; PDBTitle: crystal structure of the putative sulfatase yidj from bacteroides2 fragilis. northeast structural genomics consortium target bfr123 7 d1auka_ 100.0 18 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 8 c3ed4A_ 100.0 15 PDB header:transferase Chain: A: PDB Molecule:arylsulfatase; PDBTitle: crystal structure of putative arylsulfatase from escherichia coli 9 d1fsua_ 100.0 14 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 10 c3b5qB_ 100.0 10 PDB header:hydrolase Chain: B: PDB Molecule:putative sulfatase yidj; PDBTitle: crystal structure of a putative sulfatase (np_810509.1)2 from bacteroides thetaiotaomicron vpi-5482 at 2.40 a3 resolution 11 c2vqrA_ 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:putative sulfatase; PDBTitle: crystal structure of a phosphonate monoester hydrolase2 from rhizobium leguminosarum: a new member of the3 alkaline phosphatase superfamily 12 c3lxqB_ 100.0 17 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein vp1736; PDBTitle: the crystal structure of a protein in the alkaline2 phosphatase superfamily from vibrio parahaemolyticus to3 1.95a 13 c2w8dB_ 100.0 14 PDB header:transferase Chain: B: PDB Molecule:processed glycerol phosphate lipoteichoic acid synthase 2; PDBTitle: distinct and essential morphogenic functions for wall- and2 lipo-teichoic acids in bacillus subtilis 14 c2w5tA_ 100.0 17 PDB header:transferase Chain: A: PDB Molecule:processed glycerol phosphate lipoteichoic acid PDBTitle: structure-based mechanism of lipoteichoic acid synthesis by2 staphylococcus aureus ltas. 15 d2i09a1 100.0 37 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:DeoB catalytic domain-like 16 c3q3qA_ 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:alkaline phosphatase; PDBTitle: crystal structure of spap: an novel alkaline phosphatase from2 bacterium sphingomonas sp. strain bsar-1 17 d1o98a2 100.0 18 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, catalytic domain 18 c2gsoB_ 100.0 12 PDB header:hydrolase Chain: B: PDB Molecule:phosphodiesterase-nucleotide pyrophosphatase; PDBTitle: structure of xac nucleotide2 pyrophosphatase/phosphodiesterase in complex with vanadate 19 c3szzA_ 100.0 13 PDB header:hydrolase Chain: A: PDB Molecule:phosphonoacetate hydrolase; PDBTitle: crystal structure of phosphonoacetate hydrolase from sinorhizobium2 meliloti 1021 in complex with acetate 20 c2xrgA_ 100.0 19 PDB header:hydrolase Chain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) in complex with the2 ha155 boronic acid inhibitor 21 d1ei6a_ not modelled 100.0 12 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Phosphonoacetate hydrolase 22 c2xr9A_ not modelled 100.0 18 PDB header:hydrolase Chain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) 23 c1o98A_ not modelled 99.9 24 PDB header:isomerase Chain: A: PDB Molecule:2,3-bisphosphoglycerate-independent PDBTitle: 1.4a crystal structure of phosphoglycerate mutase from2 bacillus stearothermophilus complexed with3 2-phosphoglycerate 24 c3iddA_ not modelled 99.9 19 PDB header:isomerase Chain: A: PDB Molecule:2,3-bisphosphoglycerate-independent PDBTitle: cofactor-independent phosphoglycerate mutase from2 thermoplasma acidophilum dsm 1728 25 c3igzB_ not modelled 99.9 26 PDB header:isomerase Chain: B: PDB Molecule:cofactor-independent phosphoglycerate mutase; PDBTitle: crystal structures of leishmania mexicana phosphoglycerate2 mutase at low cobalt concentration 26 d1zeda1 not modelled 99.5 16 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Alkaline phosphatase 27 d1y6va1 not modelled 99.5 16 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Alkaline phosphatase 28 c1ew2A_ not modelled 99.5 16 PDB header:hydrolase Chain: A: PDB Molecule:phosphatase; PDBTitle: crystal structure of a human phosphatase 29 c2d1gB_ not modelled 99.4 12 PDB header:hydrolase Chain: B: PDB Molecule:acid phosphatase; PDBTitle: structure of francisella tularensis acid phosphatase a (acpa) bound to2 orthovanadate 30 c2iucB_ not modelled 99.4 15 PDB header:hydrolase Chain: B: PDB Molecule:alkaline phosphatase; PDBTitle: structure of alkaline phosphatase from the antarctic2 bacterium tab5 31 d1k7ha_ not modelled 99.4 16 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Alkaline phosphatase 32 c3a52A_ not modelled 99.2 20 PDB header:hydrolase Chain: A: PDB Molecule:cold-active alkaline phosphatase; PDBTitle: crystal structure of cold-active alkailne phosphatase from2 psychrophile shewanella sp. 33 c3e2dB_ not modelled 99.2 17 PDB header:hydrolase Chain: B: PDB Molecule:alkaline phosphatase; PDBTitle: the 1.4 a crystal structure of the large and cold-active2 vibrio sp. alkaline phosphatase 34 c2w0yB_ not modelled 99.2 19 PDB header:hydrolase Chain: B: PDB Molecule:alkaline phosphatase; PDBTitle: h.salinarum alkaline phosphatase 35 c2x98A_ not modelled 99.1 18 PDB header:hydrolase Chain: A: PDB Molecule:alkaline phosphatase; PDBTitle: h.salinarum alkaline phosphatase 36 d2i09a2 not modelled 98.6 44 Fold:DeoB insert domain-like Superfamily:DeoB insert domain-like Family:DeoB insert domain-like 37 d1b4ub_ not modelled 62.6 10 Fold:Phosphorylase/hydrolase-like Superfamily:LigB-like Family:LigB-like 38 c3oaaO_ not modelled 60.2 18 PDB header:hydrolase/transport protein Chain: O: PDB Molecule:atp synthase gamma chain; PDBTitle: structure of the e.coli f1-atp synthase inhibited by subunit epsilon 39 d1fs0g_ not modelled 33.7 16 Fold:Pyruvate kinase C-terminal domain-like Superfamily:ATP synthase (F1-ATPase), gamma subunit Family:ATP synthase (F1-ATPase), gamma subunit 40 c2xokG_ not modelled 30.3 31 PDB header:hydrolase Chain: G: PDB Molecule:atp synthase subunit gamma, mitochondrial; PDBTitle: refined structure of yeast f1c10 atpase complex to 3 a2 resolution 41 c3e20C_ not modelled 27.3 12 PDB header:translation Chain: C: PDB Molecule:eukaryotic peptide chain release factor subunit 1; PDBTitle: crystal structure of s.pombe erf1/erf3 complex 42 d1t6la1 not modelled 27.1 11 Fold:DNA clamp Superfamily:DNA clamp Family:DNA polymerase processivity factor 43 c3f5dA_ not modelled 23.4 33 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:protein ydea; PDBTitle: crystal structure of a protein of unknown function from2 bacillus subtilis 44 d1nfga2 not modelled 22.9 19 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 45 c2vbgB_ not modelled 22.5 8 PDB header:lyase Chain: B: PDB Molecule:branched-chain alpha-ketoacid decarboxylase; PDBTitle: the complex structure of the branched-chain keto acid2 decarboxylase (kdca) from lactococcus lactis with 2r-1-3 hydroxyethyl-deazathdp 46 c3jzeC_ not modelled 22.5 16 PDB header:hydrolase Chain: C: PDB Molecule:dihydroorotase; PDBTitle: 1.8 angstrom resolution crystal structure of dihydroorotase (pyrc)2 from salmonella enterica subsp. enterica serovar typhimurium str. lt2 47 d1j33a_ not modelled 22.3 30 Fold:Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) Superfamily:Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) Family:Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) 48 c1ovmC_ not modelled 22.1 12 PDB header:lyase Chain: C: PDB Molecule:indole-3-pyruvate decarboxylase; PDBTitle: crystal structure of indolepyruvate decarboxylase from2 enterobacter cloacae 49 d1ovma3 not modelled 21.6 12 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module 50 c1zzgB_ not modelled 21.4 13 PDB header:isomerase Chain: B: PDB Molecule:glucose-6-phosphate isomerase; PDBTitle: crystal structure of hypothetical protein tt0462 from thermus2 thermophilus hb8 51 c3pnuA_ not modelled 20.6 14 PDB header:hydrolase Chain: A: PDB Molecule:dihydroorotase; PDBTitle: 2.4 angstrom crystal structure of dihydroorotase (pyrc) from2 campylobacter jejuni. 52 d1dt9a3 not modelled 20.4 4 Fold:N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 Superfamily:N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 Family:N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 53 d2ji7a3 not modelled 20.4 12 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module 54 c3cagF_ not modelled 20.2 24 PDB header:dna binding protein Chain: F: PDB Molecule:arginine repressor; PDBTitle: crystal structure of the oligomerization domain hexamer of the2 arginine repressor protein from mycobacterium tuberculosis in complex3 with 9 arginines. 55 d2jdig1 not modelled 20.1 22 Fold:Pyruvate kinase C-terminal domain-like Superfamily:ATP synthase (F1-ATPase), gamma subunit Family:ATP synthase (F1-ATPase), gamma subunit 56 d2p5ma1 not modelled 19.9 38 Fold:DCoH-like Superfamily:C-terminal domain of arginine repressor Family:C-terminal domain of arginine repressor 57 d1b4ba_ not modelled 19.1 29 Fold:DCoH-like Superfamily:C-terminal domain of arginine repressor Family:C-terminal domain of arginine repressor 58 c3ff1B_ not modelled 19.1 21 PDB header:isomerase Chain: B: PDB Molecule:glucose-6-phosphate isomerase; PDBTitle: structure of glucose 6-phosphate isomerase from staphylococcus aureus 59 c2w6jG_ not modelled 18.5 21 PDB header:hydrolase Chain: G: PDB Molecule:atp synthase subunit gamma, mitochondrial; PDBTitle: low resolution structures of bovine mitochondrial f1-atpase2 during controlled dehydration: hydration state 5. 60 c3eyaE_ not modelled 18.3 11 PDB header:oxidoreductase Chain: E: PDB Molecule:pyruvate dehydrogenase [cytochrome]; PDBTitle: structural basis for membrane binding and catalytic2 activation of the peripheral membrane enzyme pyruvate3 oxidase from escherichia coli 61 c2q8nB_ not modelled 17.4 4 PDB header:isomerase Chain: B: PDB Molecule:glucose-6-phosphate isomerase; PDBTitle: crystal structure of glucose-6-phosphate isomerase (ec2 5.3.1.9) (tm1385) from thermotoga maritima at 1.82 a3 resolution 62 d1c7qa_ not modelled 17.4 17 Fold:SIS domain Superfamily:SIS domain Family:Phosphoglucose isomerase, PGI 63 d2pg4a1 not modelled 17.2 20 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:F93-like 64 c3ereD_ not modelled 16.0 24 PDB header:dna binding protein/dna Chain: D: PDB Molecule:arginine repressor; PDBTitle: crystal structure of the arginine repressor protein from mycobacterium2 tuberculosis in complex with the dna operator 65 c3p19A_ not modelled 16.0 34 PDB header:oxidoreductase Chain: A: PDB Molecule:putative blue fluorescent protein; PDBTitle: improved nadph-dependent blue fluorescent protein 66 c2o2cB_ not modelled 15.6 8 PDB header:isomerase Chain: B: PDB Molecule:glucose-6-phosphate isomerase, glycosomal; PDBTitle: crystal structure of phosphoglucose isomerase from t. brucei2 containing glucose-6-phosphate in the active site 67 d1l5oa_ not modelled 15.5 50 Fold:Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) Superfamily:Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) Family:Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) 68 d1dc1a_ not modelled 15.1 26 Fold:Restriction endonuclease-like Superfamily:Restriction endonuclease-like Family:Restriction endonuclease BsobI 69 d2eg6a1 not modelled 14.7 19 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Dihydroorotase 70 c2f00A_ not modelled 13.8 10 PDB header:ligase Chain: A: PDB Molecule:udp-n-acetylmuramate--l-alanine ligase; PDBTitle: escherichia coli murc 71 c1yypA_ not modelled 13.8 11 PDB header:replication/transferase Chain: A: PDB Molecule:dna polymerase processivity factor; PDBTitle: crystal structure of cytomegalovirus ul44 bound to c-terminal peptide2 from cmv ul54 72 c3nbuC_ not modelled 13.8 4 PDB header:isomerase Chain: C: PDB Molecule:glucose-6-phosphate isomerase; PDBTitle: crystal structure of pgi glucosephosphate isomerase 73 c2nxwB_ not modelled 13.5 12 PDB header:lyase Chain: B: PDB Molecule:phenyl-3-pyruvate decarboxylase; PDBTitle: crystal structure of phenylpyruvate decarboxylase of azospirillum2 brasilense 74 c3hjbA_ not modelled 12.9 4 PDB header:isomerase Chain: A: PDB Molecule:glucose-6-phosphate isomerase; PDBTitle: 1.5 angstrom crystal structure of glucose-6-phosphate isomerase from2 vibrio cholerae. 75 d1u0fa_ not modelled 12.9 8 Fold:SIS domain Superfamily:SIS domain Family:Phosphoglucose isomerase, PGI 76 d2ez9a3 not modelled 12.8 13 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module 77 d1gkra2 not modelled 12.7 28 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 78 d1hm5a_ not modelled 12.5 8 Fold:SIS domain Superfamily:SIS domain Family:Phosphoglucose isomerase, PGI 79 d1ynya2 not modelled 12.5 20 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 80 d1q50a_ not modelled 12.4 13 Fold:SIS domain Superfamily:SIS domain Family:Phosphoglucose isomerase, PGI 81 c2qe7G_ not modelled 12.3 27 PDB header:hydrolase Chain: G: PDB Molecule:atp synthase subunit gamma; PDBTitle: crystal structure of the f1-atpase from the thermoalkaliphilic2 bacterium bacillus sp. ta2.a1 82 c1t10A_ not modelled 12.3 13 PDB header:isomerase Chain: A: PDB Molecule:glucose-6-phosphate isomerase; PDBTitle: phosphoglucose isomerase from leishmania mexicana in complex with2 substrate d-fructose-6-phosphate 83 c2w93A_ not modelled 12.3 8 PDB header:lyase Chain: A: PDB Molecule:pyruvate decarboxylase isozyme 1; PDBTitle: crystal structure of the saccharomyces cerevisiae pyruvate2 decarboxylase variant e477q in complex with the surrogate3 pyruvamide 84 c2ejbA_ not modelled 12.2 16 PDB header:lyase Chain: A: PDB Molecule:probable aromatic acid decarboxylase; PDBTitle: crystal structure of phenylacrylic acid decarboxylase from2 aquifex aeolicus 85 c3ljkA_ not modelled 12.2 13 PDB header:isomerase Chain: A: PDB Molecule:glucose-6-phosphate isomerase; PDBTitle: glucose-6-phosphate isomerase from francisella tularensis. 86 d1jsca3 not modelled 12.0 9 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module 87 c1b4aA_ not modelled 11.7 29 PDB header:repressor Chain: A: PDB Molecule:arginine repressor; PDBTitle: structure of the arginine repressor from bacillus stearothermophilus 88 d1iata_ not modelled 11.7 8 Fold:SIS domain Superfamily:SIS domain Family:Phosphoglucose isomerase, PGI 89 c3kpgA_ not modelled 11.5 23 PDB header:oxidoreductase Chain: A: PDB Molecule:sulfide-quinone reductase, putative; PDBTitle: crystal structure of sulfide:quinone oxidoreductase from2 acidithiobacillus ferrooxidans in complex with decylubiquinone 90 c2ol5B_ not modelled 11.3 12 PDB header:transcription regulator Chain: B: PDB Molecule:pai 2 protein; PDBTitle: crystal structure of a protease synthase and sporulation negative2 regulatory protein pai 2 from bacillus stearothermophilus 91 d1xxaa_ not modelled 11.3 29 Fold:DCoH-like Superfamily:C-terminal domain of arginine repressor Family:C-terminal domain of arginine repressor 92 d1t9ba3 not modelled 11.3 10 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module 93 c3zquA_ not modelled 11.2 21 PDB header:lyase Chain: A: PDB Molecule:probable aromatic acid decarboxylase; PDBTitle: structure of a probable aromatic acid decarboxylase 94 d2hxma1 not modelled 11.1 4 Fold:Uracil-DNA glycosylase-like Superfamily:Uracil-DNA glycosylase-like Family:Uracil-DNA glycosylase 95 d1laue_ not modelled 10.7 8 Fold:Uracil-DNA glycosylase-like Superfamily:Uracil-DNA glycosylase-like Family:Uracil-DNA glycosylase 96 d1k1da2 not modelled 10.5 22 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 97 d1gzda_ not modelled 10.4 8 Fold:SIS domain Superfamily:SIS domain Family:Phosphoglucose isomerase, PGI 98 c2pgnA_ not modelled 10.2 10 PDB header:hydrolase Chain: A: PDB Molecule:cyclohexane-1,2-dione hydrolase (cdh); PDBTitle: the crystal structure of fad and thdp-dependent cyclohexane-1,2-dione2 hydrolase in complex with cyclohexane-1,2-dione 99 d1q6za3 not modelled 10.1 13 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0