BLASTP 2.2.22 [Sep-27-2009]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= batch____
         (293 letters)

Database: uniref50.fasta 
           3,077,464 sequences; 1,040,396,356 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q5DIE4 Glucose-1-phosphate thymidylyltransferase n=109 ...   449   e-125
UniRef50_P55253 Glucose-1-phosphate thymidylyltransferase n=1508...   397   e-109
UniRef50_Q6MF02 Glucose-1-phosphate thymidylyltransferase n=3 Ta...   355   1e-96
UniRef50_C7XIA2 Glucose-1-phosphate thymidylyltransferase n=1 Ta...   336   6e-91
UniRef50_C0LTM3 Glucose-1-phosphate thymidylyltransferase n=6 Ta...   323   5e-87
UniRef50_Q9ZAE7 Glucose-1-phosphate thymidylyltransferase n=12 T...   323   5e-87
UniRef50_D1Y1R8 Glucose-1-phosphate thymidylyltransferase n=1 Ta...   308   2e-82
UniRef50_C7IJC3 Glucose-1-phosphate thymidylyltransferase n=1 Ta...   303   6e-81
UniRef50_Q9X3S7 Glucose-1-phosphate thymidyl transferase n=1 Tax...   291   1e-77
UniRef50_UPI0001C3666A glucose-1-phosphate thymidylyltransferase...   271   1e-71
UniRef50_D0RRF5 Glucose-1-phosphate thymidylyltransferase (DTDP-...   249   6e-65
UniRef50_Q01T68 Nucleotidyl transferase n=8 Tax=cellular organis...   211   2e-53
UniRef50_B9KYJ6 Glucose-1-phosphate thymidylyltransferase n=5 Ta...   203   5e-51
UniRef50_A8FIL3 Spore coat polysaccharide biosynthesis protein S...   203   5e-51
UniRef50_P39629 Spore coat polysaccharide biosynthesis protein s...   203   6e-51
UniRef50_Q8CUH8 Spore coat polysaccharide synthesis (Glucose-1-p...   199   1e-49
UniRef50_C7U1N1 RmlA protein n=1 Tax=Rhodococcus aetherivorans R...   183   8e-45
UniRef50_Q55689 Glucose-1-phosphate thymidylyltransferase n=52 T...   164   5e-39
UniRef50_A7HN10 Glucose-1-phosphate thymidyltransferase n=9 Tax=...   163   8e-39
UniRef50_C7NU65 Glucose-1-phosphate thymidyltransferase n=5 Tax=...   157   5e-37
UniRef50_A5D3D6 dTDP-glucose pyrophosphorylase n=5 Tax=Bacteria ...   156   7e-37
UniRef50_UPI000038E60D glucose-1-phosphate thymidylyltransferase...   156   7e-37
UniRef50_P08075 Glucose-1-phosphate thymidylyltransferase n=49 T...   154   3e-36
UniRef50_A7GF11 Glucose-1-phosphate thymidylyltransferase n=9 Ta...   146   8e-34
UniRef50_C0ZCI7 Probable glucose-1-phosphate thymidylyltransfera...   146   1e-33
UniRef50_A4YHT6 Glucose-1-phosphate thymidyltransferase n=1 Tax=...   145   1e-33
UniRef50_B5GLJ2 NDP-1-glucose synthase n=1 Tax=Streptomyces clav...   145   2e-33
UniRef50_O29921 Glucose-1-phosphate thymidylyltransferase (GraD-...   144   4e-33
UniRef50_A9A1Q3 Glucose-1-phosphate thymidyltransferase n=1 Tax=...   140   4e-32
UniRef50_Q97A91 Glucose-1-phosphate thymidylyltransferase n=2 Ta...   136   1e-30
UniRef50_C6D3B0 Nucleotidyl transferase n=1 Tax=Paenibacillus sp...   135   2e-30
UniRef50_B0BLL5 dTDP-1-glucose synthase n=1 Tax=Actinomadura mad...   131   3e-29
UniRef50_A8LZU8 Glucose-1-phosphate thymidyltransferase n=15 Tax...   130   5e-29
UniRef50_Q46AY8 Glucose-1-phosphate thymidylyltransferase n=4 Ta...   124   5e-27
UniRef50_UPI0001693120 glucose-1-phosphate thymidyltransferase n...   123   7e-27
UniRef50_D2PJ00 Glucose-1-phosphate thymidyltransferase n=15 Tax...   121   3e-26
UniRef50_Q1J1J1 Glucose-1-phosphate thymidyltransferase n=10 Tax...   120   7e-26
UniRef50_A8A970 Nucleotidyl transferase n=1 Tax=Ignicoccus hospi...   118   2e-25
UniRef50_Q1J1Y9 Nucleotidyl transferase n=2 Tax=Deinococcus RepI...   117   3e-25
UniRef50_C8PNG7 Glucose-1-phosphate thymidylyltransferase n=1 Ta...   117   5e-25
UniRef50_Q9YCT0 Glucose-1-phosphate thymidylyltransferase n=1 Ta...   115   2e-24
UniRef50_UPI0001C418F3 UDP-N-acetylglucosamine diphosphorylase/g...   111   3e-23
UniRef50_A3CRY9 UDP-glucose pyrophosphorylase n=2 Tax=Methanomic...   108   3e-22
UniRef50_Q7BM20 STMD1.67 protein n=18 Tax=Gammaproteobacteria Re...   106   1e-21
UniRef50_Q048R4 Glucose-1-phosphate thymidylyltransferase n=2 Ta...   105   1e-21
UniRef50_Q9KD03 Mannose-1-phosphate guanyltransferase n=1 Tax=Ba...   100   1e-19
UniRef50_D2RY68 Nucleotidyl transferase n=2 Tax=Halobacteriaceae...    98   3e-19
UniRef50_A6UUQ4 Glucosamine-1-phosphate N-acetyltransferase n=6 ...    97   7e-19
UniRef50_A1S0Y5 UDP-glucose pyrophosphorylase n=1 Tax=Thermofilu...    97   1e-18
UniRef50_UPI0001C42A13 Nucleoside-diphosphate-sugar pyrophosphor...    96   2e-18
UniRef50_B8D6C9 Glucose-1-phosphate thymidylyltransferase n=1 Ta...    96   2e-18
UniRef50_A7GSW4 Nucleotidyl transferase n=73 Tax=cellular organi...    94   5e-18
UniRef50_A1S194 UDP-glucose pyrophosphorylase n=1 Tax=Thermofilu...    94   8e-18
UniRef50_Q2NES5 Predicted nucleoside-diphosphate-sugar pyrophosp...    93   1e-17
UniRef50_B3T1I2 Putative Nucleotidyl transferase n=1 Tax=uncultu...    92   2e-17
UniRef50_Q0W4J0 Glucose-1-phosphate thymidylyltransferase n=2 Ta...    92   2e-17
UniRef50_Q8TWY9 Nucleoside-diphosphate-sugar pyrophosphorylase i...    92   2e-17
UniRef50_C3LKU6 Nucleotidyl transferase family protein n=8 Tax=B...    92   3e-17
UniRef50_A6CNU8 Mannose-1-phosphate guanyltransferase (Pyrophosp...    91   4e-17
UniRef50_UPI0001C315BB Nucleotidyl transferase n=1 Tax=Conexibac...    91   5e-17
UniRef50_C0GGS0 Nucleotidyl transferase n=1 Tax=Dethiobacter alk...    90   9e-17
UniRef50_B9LMT7 Nucleotidyl transferase n=2 Tax=Halobacteriaceae...    90   9e-17
UniRef50_Q2FRV9 Nucleotidyl transferase n=7 Tax=cellular organis...    90   1e-16
UniRef50_Q67RD1 Glucose-1-phosphate thymidylyltransferase n=1 Ta...    90   1e-16
UniRef50_C8SCM3 Nucleotidyl transferase n=1 Tax=Ferroglobus plac...    89   2e-16
UniRef50_B9XHJ7 Putative glucose-1-phosphate thymidylyltransfera...    89   2e-16
UniRef50_C7P380 Nucleotidyl transferase n=20 Tax=Halobacteriacea...    89   2e-16
UniRef50_A3DK29 Nucleotidyl transferase n=13 Tax=Clostridia RepI...    89   2e-16
UniRef50_Q3AQC4 Glucose-1-phosphate thymidylyltransferase n=12 T...    88   3e-16
UniRef50_C7LZ98 Nucleotidyl transferase n=1 Tax=Acidimicrobium f...    88   3e-16
UniRef50_C1SHR4 Nucleotidyltransferase n=1 Tax=Denitrovibrio ace...    87   5e-16
UniRef50_D2EEQ5 Nucleotidyl transferase n=1 Tax=Candidatus Parva...    87   7e-16
UniRef50_B7GHA3 Nucleoside-diphosphate-sugar pyrophosphorylase f...    87   7e-16
UniRef50_D1JGY1 Putative bifunctional protein glmU n=1 Tax=uncul...    87   8e-16
UniRef50_Q01PZ9 UDP-glucose pyrophosphorylase n=1 Tax=Candidatus...    87   9e-16
UniRef50_C9RWA3 Nucleotidyl transferase n=7 Tax=Geobacillus RepI...    87   9e-16
UniRef50_A0Q1V6 Mannose-1-phosphate guanyltransferase (Pyrophosp...    86   1e-15
UniRef50_A8SKG5 Putative uncharacterized protein n=1 Tax=Parvimo...    86   2e-15
UniRef50_D2LMS4 Nucleotidyl transferase n=3 Tax=Aciduliprofundum...    86   2e-15
UniRef50_Q9I291 UTP--glucose-1-phosphate uridylyltransferase n=1...    86   2e-15
UniRef50_Q6MGZ2 UTP-glucose-1-phosphate uridylyltransferase n=1 ...    85   2e-15
UniRef50_Q3Z925 Glucose-1-phosphate thymidylyltransferase n=5 Ta...    85   2e-15
UniRef50_P47691 UTP--glucose-1-phosphate uridylyltransferase n=2...    85   3e-15
UniRef50_Q46AY5 Glucose-1-phosphate thymidylyltransferase n=4 Ta...    85   4e-15
UniRef50_Q8SQX7 MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE n=3 Tax=...    84   6e-15
UniRef50_A7NP37 Nucleotidyl transferase n=5 Tax=Chloroflexaceae ...    84   7e-15
UniRef50_B8CYH8 Phosphoglucomutase n=1 Tax=Halothermothrix oreni...    83   1e-14
UniRef50_C9XS92 Utp--glucose-1-phosphate uridylyltransferase (Ge...    83   1e-14
UniRef50_A6TK87 UTP-glucose-1-phosphate uridylyltransferase n=5 ...    83   1e-14
UniRef50_C4I7X9 UTP-glucose-1-phosphate uridylyltransferase n=43...    83   1e-14
UniRef50_C6A1S5 NDP-sugar synthase n=9 Tax=Thermococcaceae RepID...    82   2e-14
UniRef50_UPI000038E164 mannose-1-phosphate guanyltransferase n=1...    82   3e-14
UniRef50_P42407 Putative UTP--glucose-1-phosphate uridylyltransf...    82   3e-14
UniRef50_Q1LK18 UDP-glucose pyrophosphorylase n=21 Tax=Proteobac...    82   3e-14
UniRef50_A5N939 Predicted glucose-1-phosphate nucleotidyltransfe...    82   3e-14
UniRef50_A9A224 Nucleotidyl transferase n=3 Tax=Thaumarchaeota R...    82   3e-14
UniRef50_UPI0001912073 TDP-glucose pyrophosphorylase n=1 Tax=Sal...    81   3e-14
UniRef50_B9LW43 Nucleotidyl transferase n=5 Tax=Halobacteriaceae...    81   3e-14
UniRef50_C0ZG53 Probable mannose-1-phosphate guanyltransferase n...    81   4e-14
UniRef50_C8W233 Nucleotidyl transferase n=1 Tax=Desulfotomaculum...    81   4e-14
UniRef50_Q1MRX7 UDP-glucose pyrophosphorylase n=12 Tax=Desulfovi...    81   4e-14
UniRef50_C0G2T6 Nucleotidyl transferase n=1 Tax=Natrialba magadi...    81   4e-14
UniRef50_A8M980 Glucose-1-phosphate thymidyltransferase n=3 Tax=...    81   4e-14
UniRef50_C0GV25 dTDP-glucose pyrophosphorylase-like protein n=1 ...    81   5e-14
UniRef50_C3MRT7 Nucleotidyl transferase n=12 Tax=Sulfolobaceae R...    81   5e-14
UniRef50_Q49VP4 UTP--glucose-1-phosphate uridylyltransferase 2 n...    80   6e-14
UniRef50_A6Q9R9 Mannose-1-phosphate guanylyltransferase n=3 Tax=...    80   8e-14
UniRef50_A3DED2 Nucleotidyl transferase n=8 Tax=Clostridium RepI...    80   8e-14
UniRef50_Q58730 Putative UTP--glucose-1-phosphate uridylyltransf...    80   9e-14
UniRef50_A3DMT9 Nucleotidyl transferase n=11 Tax=Thermoprotei Re...    80   9e-14
UniRef50_A6UP85 Glucosamine-1-phosphate N-acetyltransferase n=6 ...    80   9e-14
UniRef50_C6A0S3 Nucleotidyl transferase family n=6 Tax=Thermococ...    80   1e-13
UniRef50_Q74B34 Nucleotidyltransferase family protein n=1 Tax=Ge...    80   1e-13
UniRef50_B8D5T2 Putative sugar-phosphate nucleotidyl transferase...    80   1e-13
UniRef50_UPI00016B2344 UTP-glucose-1-phosphate uridylyltransfera...    80   1e-13
UniRef50_C7NR86 Nucleotidyl transferase n=4 Tax=Halobacteriaceae...    79   1e-13
UniRef50_Q0RC10 UTP--glucose-1-phosphate uridylyltransferase (UD...    79   1e-13
UniRef50_B7J1D8 UDP-glucose pyrophosphorylase n=21 Tax=Borrelia ...    79   2e-13
UniRef50_Q3Z778 Nucleotidyltransferase family protein n=5 Tax=De...    79   2e-13
UniRef50_D1B9X0 UTP-glucose-1-phosphate uridylyltransferase n=1 ...    79   2e-13
UniRef50_B0BZX4 Phosphoglucomutase/phosphomannomutase family Nuc...    79   2e-13
UniRef50_Q12TW4 Mannose-1-phosphate guanyltransferase n=11 Tax=E...    79   3e-13
UniRef50_A7AUL2 Mannose-1-phosphate guanyltransferase, putative ...    78   3e-13
UniRef50_Q7NNE0 Mannose-1-phosphate guanyltransferase n=5 Tax=Gl...    78   3e-13
UniRef50_A8KY05 Nucleotidyl transferase n=6 Tax=Actinomycetales ...    78   4e-13
UniRef50_B2UH51 UTP-glucose-1-phosphate uridylyltransferase n=12...    78   4e-13
UniRef50_B9YXM9 Glucose-1-phosphate thymidylyltransferase n=1 Ta...    78   4e-13
UniRef50_C7PVA0 Nucleotidyl transferase n=3 Tax=Bacteroidetes Re...    78   4e-13
UniRef50_B9MMF1 Nucleotidyl transferase n=1 Tax=Anaerocellum the...    78   4e-13
UniRef50_Q3A0B4 Mannose-1-phosphate guanyltransferase n=10 Tax=D...    77   5e-13
UniRef50_Q8ILP1 Mannose-1-phosphate guanyltransferase, putative ...    77   6e-13
UniRef50_Q0W734 Nucleotidyltransferase family protein n=2 Tax=Eu...    77   6e-13
UniRef50_Q97EX5 Mannose-1-phosphate guanyltransferase (Pyrophosp...    77   8e-13
UniRef50_A9B3S0 Nucleotidyl transferase n=6 Tax=Chloroflexi (cla...    77   9e-13
UniRef50_B7XJS8 Mannose-1-phosphate guanyltransferase n=1 Tax=En...    77   9e-13
UniRef50_C1DV53 Mannose-1-phosphate guanyltransferase n=4 Tax=ce...    77   1e-12
UniRef50_C0GEN7 Nucleotidyl transferase n=1 Tax=Dethiobacter alk...    77   1e-12
UniRef50_C7LY80 Nucleotidyl transferase n=1 Tax=Acidimicrobium f...    76   1e-12
UniRef50_Q18G10 Glucose-1-phosphate thymidylyltransferase n=5 Ta...    76   1e-12
UniRef50_B3QV42 Nucleotidyl transferase n=1 Tax=Chloroherpeton t...    76   1e-12
UniRef50_B3LAG9 Mannose-1-phosphate guanyltransferase, putative ...    76   1e-12
UniRef50_Q9ZGB3 NDP-hexose synthetase homolog n=1 Tax=Streptomyc...    76   1e-12
UniRef50_Q97EQ2 Nucleoside-diphosphate-sugar pyrophosphorylase n...    76   2e-12
UniRef50_UPI0001AF5131 glucose-1-phosphate thymidylyltransferase...    76   2e-12
UniRef50_Q23RS7 Nucleotidyl transferase family protein n=3 Tax=E...    76   2e-12
UniRef50_C7M360 UTP-glucose-1-phosphate uridylyltransferase n=2 ...    76   2e-12
UniRef50_B0MQS9 Putative uncharacterized protein n=2 Tax=Clostri...    76   2e-12
UniRef50_Q54800 UTP--glucose-1-phosphate uridylyltransferase n=1...    75   2e-12
UniRef50_B4VDY2 dTDP-glucose synthase n=1 Tax=Streptomyces sp. M...    75   2e-12
UniRef50_Q0W805 Putative glucose-1-phosphate thymidylyltransfera...    75   2e-12
UniRef50_Q6L165 Mannose-1-phosphate guanyltransferase n=3 Tax=Th...    75   2e-12
UniRef50_C4RN52 UTP-glucose-1-phosphate uridylyltransferase galU...    75   3e-12
UniRef50_B6BPC5 UTP--glucose-1-phosphate uridylyltransferase n=4...    75   3e-12
UniRef50_C6CVH3 Nucleotidyl transferase n=3 Tax=Bacillales RepID...    75   3e-12
UniRef50_A4J6Z1 Nucleotidyl transferase n=3 Tax=Peptococcaceae R...    74   5e-12
UniRef50_Q8DLP2 Mannose-1-phosphate guanyltransferase n=9 Tax=Cy...    74   5e-12
UniRef50_B1XM99 Sugar-phosphate nucleotidyl transferase n=59 Tax...    74   5e-12
UniRef50_D2AV47 Phosphoglucomutase/phosphomannomutase family pro...    74   5e-12
UniRef50_C9RJ30 Nucleotidyl transferase n=1 Tax=Fibrobacter succ...    74   6e-12
UniRef50_B5GDG2 Nucleotide phosphorylase n=1 Tax=Streptomyces sp...    74   6e-12
UniRef50_A3DL04 Nucleotidyl transferase n=1 Tax=Staphylothermus ...    74   6e-12
UniRef50_Q2RH64 Nucleotidyl transferase n=1 Tax=Moorella thermoa...    74   6e-12
UniRef50_A9FF13 Putative sugar-phosphate nucleotide transferase ...    74   7e-12
UniRef50_UPI000186E54F Mannose-1-phosphate guanyltransferase, pu...    74   7e-12
UniRef50_Q2J5Q2 UDP-glucose pyrophosphorylase n=51 Tax=Bacteria ...    74   7e-12
UniRef50_C8WLR8 Nucleotidyl transferase n=3 Tax=Coriobacteriacea...    74   7e-12
UniRef50_UPI00016B22C9 glucose-1-phosphate thymidylyltransferase...    74   8e-12
UniRef50_A4YHR3 UDP-glucose pyrophosphorylase n=9 Tax=Sulfolobac...    73   9e-12
UniRef50_A4X2X2 UDP-glucose pyrophosphorylase n=3 Tax=Actinomyce...    73   1e-11
UniRef50_A6TTZ6 Nucleotidyl transferase n=1 Tax=Alkaliphilus met...    73   1e-11
UniRef50_A8GZ91 Nucleotidyl transferase n=5 Tax=Gammaproteobacte...    73   1e-11
UniRef50_A5YSR1 Sugar nucleotidyltransferase II n=1 Tax=uncultur...    73   1e-11
UniRef50_C6HYP8 UTP-glucose-1-phosphate uridylyltransferase n=1 ...    72   2e-11
UniRef50_C0QWA5 Nucleotidyltransferase n=2 Tax=Brachyspira RepID...    72   2e-11
UniRef50_Q30U75 Nucleotidyl transferase n=3 Tax=Proteobacteria R...    72   2e-11
UniRef50_Q28JE9 Nucleotidyl transferase n=1 Tax=Jannaschia sp. C...    72   2e-11
UniRef50_B0BZ78 Nucleotidyl transferase protein n=5 Tax=Cyanobac...    72   2e-11
UniRef50_D2EFH1 Nucleotidyl transferase n=1 Tax=Candidatus Parva...    72   3e-11
UniRef50_C8NLU6 Mannose-1-phosphate guanyltransferase n=88 Tax=A...    72   3e-11
UniRef50_D2LMS9 Nucleotidyl transferase n=3 Tax=Aciduliprofundum...    72   3e-11
UniRef50_Q2LPS3 Glucose-1-phosphate adenylyltransferase n=3 Tax=...    71   4e-11
UniRef50_A5URP0 Nucleotidyl transferase n=6 Tax=Bacteria RepID=A...    71   4e-11
UniRef50_Q9YCQ9 Putative nucleotidyl transferase n=1 Tax=Aeropyr...    71   4e-11
UniRef50_A6UTZ2 UTP-glucose-1-phosphate uridylyltransferase n=9 ...    71   4e-11
UniRef50_Q5UXR9 Glucose-1-phosphate thymidylyltransferase n=2 Ta...    71   5e-11
UniRef50_A0B7L5 Nucleotidyl transferase n=1 Tax=Methanosaeta the...    71   5e-11
UniRef50_C8PUN5 Utp--glucose-1-phosphate uridylyltransferase n=1...    71   5e-11
UniRef50_A8V905 UTP-glucose-1-phosphate uridylyltransferase n=3 ...    70   6e-11
UniRef50_B0R8I5 Sugar nucleotidyltransferase n=2 Tax=Halobacteri...    70   7e-11
UniRef50_B0PFA5 Putative uncharacterized protein n=1 Tax=Anaerot...    70   9e-11
UniRef50_C7ICW0 Nucleotidyl transferase n=1 Tax=Clostridium papy...    70   9e-11
UniRef50_C8NNE5 UTP-glucose-1-phosphate uridylyltransferase n=71...    70   1e-10
UniRef50_B8FX62 Glucose-1-phosphate adenylyltransferase n=2 Tax=...    70   1e-10
UniRef50_Q1AVJ3 Nucleotidyl transferase n=1 Tax=Rubrobacter xyla...    70   1e-10
UniRef50_C5A4I2 Sugar-phosphate nucleotydyltransferase n=9 Tax=T...    69   2e-10
UniRef50_A2EDD6 Nucleotidyl transferase family protein n=2 Tax=T...    69   2e-10
UniRef50_C1VEK9 Nucleoside-diphosphate-sugar pyrophosphorylase f...    69   2e-10
UniRef50_P0C0I9 UTP--glucose-1-phosphate uridylyltransferase 1 n...    69   2e-10
UniRef50_D0JBR7 UTP-glucose-1-phosphate uridylyltransferase n=2 ...    69   2e-10
UniRef50_B5HPZ4 Nucleotide phosphorylase n=1 Tax=Streptomyces sv...    69   2e-10
UniRef50_Q5YYW7 Putative UTP-glucose-1-phosphate uridylyltransfe...    69   2e-10
UniRef50_Q26CD7 Putative nucleoside diphosphate sugar pyrophosph...    69   2e-10
UniRef50_B0VGT1 Putative Mannose-1-phosphate guanylyltransferase...    69   3e-10
UniRef50_Q1AW30 Nucleotidyl transferase n=1 Tax=Rubrobacter xyla...    69   3e-10
UniRef50_A3DNE2 Nucleotidyl transferase n=8 Tax=Thermoprotei Rep...    69   3e-10
UniRef50_Q036S8 Glucose-1-phosphate adenylyltransferase n=9 Tax=...    68   3e-10
UniRef50_A1RUM7 UDP-glucose pyrophosphorylase n=1 Tax=Pyrobaculu...    68   3e-10
UniRef50_B4U0Q7 UTP--glucose-1-phosphate uridylyltransferase Has...    68   3e-10
UniRef50_Q67QD8 Putative mannose-1-phosphate guanyltransferase n...    68   3e-10
UniRef50_A9B2A2 Nucleotidyl transferase n=1 Tax=Herpetosiphon au...    68   4e-10
UniRef50_Q8YRP4 Mannose-1-phosphate guanyltransferase n=11 Tax=B...    68   4e-10
UniRef50_Q2WB86 Nucleoside-diphosphate-sugar pyrophosphorylase n...    68   4e-10
UniRef50_A9A5M8 Nucleotidyl transferase n=2 Tax=Thaumarchaeota R...    68   4e-10
UniRef50_Q9HJ96 Glucose-1-phosphate thymidylyltransferase relate...    68   5e-10
UniRef50_C6X012 Glucose-1-phosphate thymidylyltransferase n=17 T...    67   5e-10
UniRef50_Q3SPZ3 Nucleotidyl transferase n=1 Tax=Nitrobacter wino...    67   5e-10
UniRef50_Q6A5G9 Glucose-1-phosphate thymidylyltransferase n=2 Ta...    67   5e-10
UniRef50_Q4UEZ4 GDP-mannose pyrophosphorylase, putative n=2 Tax=...    67   6e-10
UniRef50_C7PZ89 Nucleotidyl transferase n=3 Tax=Actinomycetales ...    67   6e-10
UniRef50_B8I5R7 Nucleotidyl transferase n=1 Tax=Clostridium cell...    67   6e-10
UniRef50_B5YF33 Mannose-1-phosphate guanyltransferase n=2 Tax=Di...    67   6e-10
UniRef50_C7H386 UTP-glucose-1-phosphate uridylyltransferase n=2 ...    67   6e-10
UniRef50_D1C4F4 Nucleotidyl transferase n=1 Tax=Sphaerobacter th...    67   6e-10
UniRef50_A5IKI2 Glucose-1-phosphate adenylyltransferase, GlgD su...    67   8e-10
UniRef50_B3PEF2 Glucose-1-phosphate adenylyltransferase n=1 Tax=...    67   8e-10
UniRef50_B8LVX3 Mannose-1-phosphate guanylyltransferase n=2 Tax=...    67   9e-10
UniRef50_C1ABC1 Glucose-1-phosphate thymidylyltransferase n=1 Ta...    67   9e-10
UniRef50_Q0AV26 Mannose-1-phosphate guanyltransferase n=1 Tax=Sy...    67   1e-09
UniRef50_UPI0001C337A3 Nucleoside-diphosphate-sugar pyrophosphor...    66   1e-09
UniRef50_B0K747 Nucleotidyl transferase n=10 Tax=Thermoanaerobac...    66   1e-09
UniRef50_UPI0001C315B1 Nucleotidyl transferase n=1 Tax=Conexibac...    66   1e-09
UniRef50_B4D758 Nucleotidyl transferase n=1 Tax=Chthoniobacter f...    66   1e-09
UniRef50_A8M9M9 Nucleotidyl transferase n=1 Tax=Caldivirga maqui...    66   1e-09
UniRef50_C0A4C2 UTP-glucose-1-phosphate uridylyltransferase n=1 ...    66   2e-09
UniRef50_A2SRW4 UDP-glucose pyrophosphorylase n=3 Tax=Euryarchae...    66   2e-09
UniRef50_B1L6P6 Nucleotidyl transferase n=1 Tax=Candidatus Korar...    65   2e-09
UniRef50_C7DG73 Nucleotidyl transferase n=1 Tax=Candidatus Micra...    65   2e-09
UniRef50_A0LAF2 Nucleotidyl transferase n=1 Tax=Magnetococcus sp...    65   2e-09
UniRef50_B1Y7P5 Nucleotidyl transferase n=1 Tax=Leptothrix cholo...    65   2e-09
UniRef50_B3DZW7 Nucleoside-diphosphate-sugar pyrophosphorylase n...    65   2e-09
UniRef50_Q2FRV8 Nucleotidyl transferase n=1 Tax=Methanospirillum...    65   2e-09
UniRef50_A9W818 Nucleotidyl transferase n=2 Tax=Rhizobiales RepI...    65   3e-09
UniRef50_D0LZQ4 UTP-glucose-1-phosphate uridylyltransferase n=1 ...    65   3e-09
UniRef50_P37820 Putative mannose-1-phosphate guanyltransferase n...    65   3e-09
UniRef50_C1TQR0 UDP-glucose pyrophosphorylase n=1 Tax=Dethiosulf...    65   3e-09
UniRef50_A4E9G8 Putative uncharacterized protein n=1 Tax=Collins...    65   3e-09
UniRef50_A4I048 Mannose-1-phosphate guanyltransferase n=5 Tax=Le...    65   3e-09
UniRef50_Q0FE70 UTP--glucose-1-phosphate uridylyltransferase (UD...    65   3e-09
UniRef50_Q11Z52 Glucose-1-phosphate thymidyltransferase n=2 Tax=...    65   4e-09
UniRef50_Q5CTS3 Mannose-1-phosphate guanylyltransferase n=2 Tax=...    64   4e-09

>UniRef50_Q5DIE4 Glucose-1-phosphate thymidylyltransferase n=109 Tax=Bacteria
           RepID=Q5DIE4_ECOLX
          Length = 290

 Score =  449 bits (1156), Expect = e-125,   Method: Compositional matrix adjust.
 Identities = 216/287 (75%), Positives = 240/287 (83%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPM+YYP+SVLMLAGIR+IL+ITTPED   
Sbjct: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMVYYPMSVLMLAGIRDILLITTPEDLPS 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F+RLLGDGS FGI L Y  Q SPDGL QAFIIGE F+  +   LVLGDNIFFGQ F  KL
Sbjct: 61  FKRLLGDGSRFGINLSYEIQQSPDGLVQAFIIGEEFIADDKCALVLGDNIFFGQSFGRKL 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
             V +   GATVFGYQVMDPERFGVVEFD NF+A+S+EEKP  PKSNWAVTGLYFYD  V
Sbjct: 121 ESVVSGNAGATVFGYQVMDPERFGVVEFDKNFKALSIEEKPAAPKSNWAVTGLYFYDENV 180

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           V+ AK VKPS RGELEIT++N+MYLE GNL VELLGRGFAWLDTGTHDSLIEAS F+ T+
Sbjct: 181 VDMAKCVKPSARGELEITTLNEMYLEQGNLQVELLGRGFAWLDTGTHDSLIEASQFIHTI 240

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLR 287
           EKRQGFKIACLEEIA+RNGWL +  V    + ++KT YGQYLL L++
Sbjct: 241 EKRQGFKIACLEEIAYRNGWLTESEVVTYGNEMSKTNYGQYLLNLIK 287


>UniRef50_P55253 Glucose-1-phosphate thymidylyltransferase n=1508 Tax=cellular
           organisms RepID=RMLA3_ECOLX
          Length = 293

 Score =  397 bits (1021), Expect = e-109,   Method: Compositional matrix adjust.
 Identities = 195/288 (67%), Positives = 233/288 (80%), Gaps = 3/288 (1%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           KGIILAGGSGTRL+P+T  VSKQLLPIYDKPMIYYPLS LMLAGIR+ILII+TP+D   F
Sbjct: 5   KGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPRF 64

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLR 121
           Q+LLGDGS++G+ L+Y  QPSPDGLAQAFIIGE F+ G+   LVLGDNIF+G    PKL 
Sbjct: 65  QQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEDFIGGDDCALVLGDNIFYGHDL-PKLM 123

Query: 122 HVAARTE-GATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
             A   E GATVF Y V DPER+GVVEFD+N  AISLEEKP +PKSN+AVTGLYFYD+ V
Sbjct: 124 EAAVNKESGATVFAYHVNDPERYGVVEFDNNGTAISLEEKPLEPKSNYAVTGLYFYDNDV 183

Query: 181 VEYA-KQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           VE A K +KPS RGELEIT IN++Y+E G L+V ++GRG+AWLDTGTH SLIEAS F+ T
Sbjct: 184 VEMARKNLKPSARGELEITDINRIYMEQGRLSVAMMGRGYAWLDTGTHQSLIEASNFIAT 243

Query: 240 VEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLR 287
           +E+RQG K++C EEIA+R G++D E VK  A  L K  YGQYLL++++
Sbjct: 244 IEERQGLKVSCPEEIAYRKGFIDAEQVKVLAEPLKKNAYGQYLLKMIK 291


>UniRef50_Q6MF02 Glucose-1-phosphate thymidylyltransferase n=3 Tax=Bacteria
           RepID=Q6MF02_PARUW
          Length = 295

 Score =  355 bits (911), Expect = 1e-96,   Method: Compositional matrix adjust.
 Identities = 169/290 (58%), Positives = 218/290 (75%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKGI+LAGGSGTRLHP+T GV+KQLLP+Y+KPMIYYPLSVL+LA I++ILII+TPED   
Sbjct: 1   MKGIVLAGGSGTRLHPLTLGVTKQLLPVYNKPMIYYPLSVLLLAEIKDILIISTPEDMPV 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F+RLLGDGS  G++  Y  QP P+GLA+AFIIG+ F+  +  CLVLGDNIF+G   S  L
Sbjct: 61  FKRLLGDGSHLGVRFTYEMQPKPNGLAEAFIIGKDFIGKDSVCLVLGDNIFYGSHLSNLL 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           +    + EGAT+FGY+V DPER+GVVEFD   + +S+EEKPK PKS+ AVTGLYFYD++V
Sbjct: 121 KSAKEKKEGATLFGYEVKDPERYGVVEFDGQGKILSIEEKPKIPKSSIAVTGLYFYDNQV 180

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           V+ A  +KPS RGELEIT +NQ YL      V ++GRG+ WLD GT++SL++AS FVQ +
Sbjct: 181 VDIAHGLKPSARGELEITDVNQEYLNRDQACVHVMGRGYTWLDAGTYESLMQASQFVQVI 240

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRARP 290
           E+RQG  IA LEEIA+   ++    +K     L K+ YG+YL+E+    P
Sbjct: 241 EQRQGHCIASLEEIAYNQKFISQAQLKLLGEKLGKSLYGRYLMEIAEKGP 290


>UniRef50_C7XIA2 Glucose-1-phosphate thymidylyltransferase n=1 Tax=Lactobacillus
           crispatus 125-2-CHN RepID=C7XIA2_9LACO
          Length = 270

 Score =  336 bits (861), Expect = 6e-91,   Method: Compositional matrix adjust.
 Identities = 166/291 (57%), Positives = 209/291 (71%), Gaps = 22/291 (7%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKGIILAGGSGTRL+P+T   SKQLLP+YDKPMIYYPLS LMLAGI++ILII+TP D   
Sbjct: 1   MKGIILAGGSGTRLYPLTLVTSKQLLPVYDKPMIYYPLSTLMLAGIKDILIISTPADTPR 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F++LLGDGS+FGI+L Y  QPSPDG AQAF +G+ F+NGEP  ++LGDNIF+G GF+  L
Sbjct: 61  FEKLLGDGSQFGIKLSYKVQPSPDGWAQAFTLGKDFINGEPCAMILGDNIFYGNGFTKLL 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           +  AA                         N +AIS+EEKP+ PKSN+AVTGLYFY + V
Sbjct: 121 KQAAADAR----------------------NGKAISIEEKPEHPKSNYAVTGLYFYPAGV 158

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            E A QVKPS RGE+EITS+N MYL+ GNL V+LLGRG+AWLD GT  SL++AS +V+ V
Sbjct: 159 SEKAAQVKPSARGEIEITSLNDMYLQEGNLDVQLLGRGYAWLDAGTMQSLVDASNYVKMV 218

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRARPR 291
           E+RQG  I+  EEIA+ +GW+D + +  AA    K+ YGQ+L  +   + R
Sbjct: 219 EERQGVSISAPEEIAYIHGWIDKDKLLDAAKHYGKSPYGQHLKSVAEGKLR 269


>UniRef50_C0LTM3 Glucose-1-phosphate thymidylyltransferase n=6 Tax=Actinomycetales
           RepID=C0LTM3_9ACTO
          Length = 331

 Score =  323 bits (827), Expect = 5e-87,   Method: Compositional matrix adjust.
 Identities = 157/290 (54%), Positives = 203/290 (70%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKGII+AGGSG+RL P+T  +SKQLLP+Y+KPMIYYPLSVLMLAG+ E+LII++P+    
Sbjct: 1   MKGIIMAGGSGSRLKPLTGVLSKQLLPVYNKPMIYYPLSVLMLAGVTEVLIISSPQHLPL 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F+ +LGDG   G++L YAEQ  P G+A+AF+IG   +  +   LVLGDNIF G GFS  L
Sbjct: 61  FRAMLGDGDRLGMRLTYAEQHRPAGIAEAFLIGAGHIGDDSVSLVLGDNIFHGPGFSALL 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           R  A R +G T+FGY V DP R+GV   D       +EEKP +P+S  AVTGLY YD+ V
Sbjct: 121 REQARRVDGCTLFGYPVRDPHRYGVAVVDSGGHLTDIEEKPDRPRSELAVTGLYMYDNDV 180

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           V  A+ ++PS RGELE+T IN+ YLE G   +  LGRGF WLDTGTH++L+EA  +V  +
Sbjct: 181 VGIARGLRPSARGELEVTDINRAYLERGKARLVQLGRGFVWLDTGTHEALLEAGQYVHIL 240

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRARP 290
           E+RQ  +IACLEEIA+R G++D   ++R     A T YG YL E+    P
Sbjct: 241 EQRQSVRIACLEEIAFRMGFIDRAALQRLGREHADTDYGAYLTEIADKPP 290


>UniRef50_Q9ZAE7 Glucose-1-phosphate thymidylyltransferase n=12 Tax=cellular
           organisms RepID=ACBA_ACTS5
          Length = 303

 Score =  323 bits (827), Expect = 5e-87,   Method: Compositional matrix adjust.
 Identities = 157/285 (55%), Positives = 203/285 (71%), Gaps = 1/285 (0%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+GI+LAGG+G+RL P+T  VSKQL+P+YDKPMIYYPL+ L+  GIREIL+ITT  +   
Sbjct: 1   MRGILLAGGTGSRLRPVTWAVSKQLMPVYDKPMIYYPLATLVSCGIREILVITTETEAAQ 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           FQRLLGDGS++G++LE+A Q  P G+A+AF+IGE FL G P  L+LGDN+  G  F P +
Sbjct: 61  FQRLLGDGSQWGLRLEFAVQQRPGGIAEAFLIGEEFLAGGPVALMLGDNLLHGVDFRPCV 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           +  A  T G  VFG  V DP  +GVVEFD   R +S+EEKP +P+S +AV G Y YD+ V
Sbjct: 121 QR-ARETAGGHVFGVAVADPSAYGVVEFDAAGRVLSIEEKPVRPRSPYAVPGFYLYDADV 179

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           VE A+ ++PS RGELEIT +NQ YL  G L+V LLGRG  WLDTGT    + A  +V+ +
Sbjct: 180 VETARSLRPSARGELEITEVNQAYLRRGALSVTLLGRGAVWLDTGTLADCMRAVDYVRAI 239

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLEL 285
           ++ QG KI C+EE AWR G+LD   ++  A  L  +GYGQYLL L
Sbjct: 240 DEGQGIKIGCVEEAAWRAGFLDTAQLRALAEPLMSSGYGQYLLAL 284


>UniRef50_D1Y1R8 Glucose-1-phosphate thymidylyltransferase n=1 Tax=Pyramidobacter
           piscolens W5455 RepID=D1Y1R8_9BACT
          Length = 295

 Score =  308 bits (789), Expect = 2e-82,   Method: Compositional matrix adjust.
 Identities = 146/287 (50%), Positives = 204/287 (71%), Gaps = 4/287 (1%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           KG+ILA G GTRLHP+T  V+KQL+P+YDKPMIYY + VL+ AG+R+I+++T+  DK  F
Sbjct: 4   KGVILAAGLGTRLHPMTLAVNKQLIPVYDKPMIYYAIWVLIKAGVRDIMLVTSEVDKNSF 63

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLR 121
           +RLLGDGS FGI + Y  Q  P+GL  AF+  E F+ G+P  L+LGDNIF+G GF   L 
Sbjct: 64  ERLLGDGSRFGIHMHYTVQYVPNGLVDAFVQTEDFIAGDPCVLILGDNIFYGSGFPAMLS 123

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVV 181
             +A+ EGATVFG  V DPERFGV  F++  + ++LEEKP  PKSN AV GLYF+D KV+
Sbjct: 124 KASAQMEGATVFGANVPDPERFGVASFNEEGKVLTLEEKPVHPKSNCAVVGLYFFDGKVM 183

Query: 182 EYAKQVK---PSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +YA +++   P+++ E+ IT +N++Y+E G L +++  +GFAWLD+GT+DSL+EAS +V 
Sbjct: 184 QYAHELRRQIPADK-EVSITDVNRVYMEQGKLDLQVFPQGFAWLDSGTYDSLLEASNYVA 242

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLEL 285
            VE+ QG  I C EE A+  G+L  E ++    +     YG+YL +L
Sbjct: 243 RVEREQGHMICCPEEAAYSAGFLALEKLREYGEADKNNNYGRYLTKL 289


>UniRef50_C7IJC3 Glucose-1-phosphate thymidylyltransferase n=1 Tax=Clostridium
           papyrosolvens DSM 2782 RepID=C7IJC3_9CLOT
          Length = 285

 Score =  303 bits (775), Expect = 6e-81,   Method: Compositional matrix adjust.
 Identities = 143/285 (50%), Positives = 194/285 (68%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK IILAGG G+R++P T  +SK L  IYDKPMIYY  S+ ++AGI E+LII   E    
Sbjct: 1   MKAIILAGGKGSRMYPATVAISKHLFLIYDKPMIYYSFSIALMAGINEVLIIAGNEHIEA 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F+ L GDGS  GI +EY  Q  P G+A+AFIIGE F+  +  CL+LGDN F+G  F   L
Sbjct: 61  FRNLFGDGSNLGIHIEYRIQDEPRGIAEAFIIGEKFIGNDSVCLILGDNFFYGDSFVYHL 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           + ++   EGA +F YQ  +PE FGVVEFD+  R +S++EK K   SN+ V G+YFYD+ V
Sbjct: 121 KALSQLKEGAGIFAYQEKNPEEFGVVEFDETGRVLSIKEKSKDSNSNYVVPGVYFYDNHV 180

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           +E AK +KPS+RGELEIT++N +YLE G L VE+L     WLDTG++++L+EAS FV++V
Sbjct: 181 IEVAKSIKPSKRGELEITTVNNVYLEKGKLKVEVLPPDVKWLDTGSYETLLEASNFVKSV 240

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLEL 285
           +   G  I+CLEEI+++N ++    V  AA     T Y +YLL +
Sbjct: 241 QTETGNMISCLEEISYKNRFIGKSEVAMAAEKYKGTQYSEYLLSI 285


>UniRef50_Q9X3S7 Glucose-1-phosphate thymidyl transferase n=1 Tax=Neisseria
           meningitidis RepID=Q9X3S7_NEIME
          Length = 298

 Score =  291 bits (746), Expect = 1e-77,   Method: Compositional matrix adjust.
 Identities = 134/175 (76%), Positives = 155/175 (88%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKGIILAGGSGTRL+PITRGVSKQLLP+YDKPMIYYPLSVLMLAGIR+IL+IT PED   
Sbjct: 14  MKGIILAGGSGTRLYPITRGVSKQLLPVYDKPMIYYPLSVLMLAGIRDILVITAPEDNAS 73

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F+RLLGDGS+FGI + YA QPSPDGLAQAFIIGE F+  +  CLVLGDNIF+GQ F+  L
Sbjct: 74  FKRLLGDGSDFGISISYAVQPSPDGLAQAFIIGEEFIGNDNVCLVLGDNIFYGQSFTQTL 133

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYF 175
           +  AA+T GATVF YQV +PERFGVVEF++NFRA+S+EEKP++PKS+WAVTGLYF
Sbjct: 134 KQAAAQTHGATVFAYQVKNPERFGVVEFNENFRAVSIEEKPQRPKSDWAVTGLYF 188


>UniRef50_UPI0001C3666A glucose-1-phosphate thymidylyltransferase n=1 Tax=Clostridium
           hathewayi DSM 13479 RepID=UPI0001C3666A
          Length = 291

 Score =  271 bits (694), Expect = 1e-71,   Method: Compositional matrix adjust.
 Identities = 133/188 (70%), Positives = 154/188 (81%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKGIILAGGSGTRL+P+T   SKQLLPIYDKPMIYYPLSVLM AGIR+ILII+TP+D   
Sbjct: 1   MKGIILAGGSGTRLYPLTMVTSKQLLPIYDKPMIYYPLSVLMNAGIRDILIISTPDDTPR 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F+ LLG GS+FGI+L YA QPSPDGLAQAFIIGE F+  +   ++LGDNIF G G + +L
Sbjct: 61  FEALLGSGSQFGIRLSYAVQPSPDGLAQAFIIGEEFIGDDNVAMILGDNIFAGHGLTKRL 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
              A + EGATVFGY V DPERFG+VEFD N +AIS+EEKP+ PKSN+ VTGLYFYD+KV
Sbjct: 121 LAAANKKEGATVFGYYVDDPERFGIVEFDSNGKAISIEEKPEHPKSNYCVTGLYFYDNKV 180

Query: 181 VEYAKQVK 188
           VEYAK  K
Sbjct: 181 VEYAKNFK 188


>UniRef50_D0RRF5 Glucose-1-phosphate thymidylyltransferase (DTDP-glucosesynthase)
           (DTDP-glucose pyrophosphorylase) n=1 Tax=alpha
           proteobacterium HIMB114 RepID=D0RRF5_9RICK
          Length = 294

 Score =  249 bits (637), Expect = 6e-65,   Method: Compositional matrix adjust.
 Identities = 125/286 (43%), Positives = 174/286 (60%), Gaps = 1/286 (0%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           KGIILAGG GTRL PIT+  +KQLLPIYDKP+ +YPLS+LMLA IR IL+I     K  F
Sbjct: 4   KGIILAGGKGTRLSPITKSTNKQLLPIYDKPLFFYPLSILMLADIRNILLIINKGQKKNF 63

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLR 121
             ++GDG   G+++ Y EQ  P G+ +AF IG+ F+      L+LGDN F+GQ  +  L+
Sbjct: 64  INVVGDGRHLGLKISYEEQLKPSGIPEAFKIGKKFIGNSNVSLILGDNFFYGQSLTELLQ 123

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVV 181
                 +G TVF   V  PE +GV +  D  + + + EKPK+  S+ A+TGLYF+D+ VV
Sbjct: 124 TTKVFKKGCTVFLKGVSKPENYGVAKIKDK-KIVEIIEKPKKFISDKAITGLYFFDNHVV 182

Query: 182 EYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVE 241
           + A ++KPS+R E EI  + + Y +   L    LGRG  W D G  D     S FV +VE
Sbjct: 183 QIAHKLKPSKRKETEIVDVIKNYKKRNCLNFIELGRGAIWSDAGKIDDFTNISNFVTSVE 242

Query: 242 KRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLR 287
           K QG KIACL+EIA++  W+  + + +      +  Y  YL +++ 
Sbjct: 243 KVQGIKIACLDEIAYQKKWITKKQILKNIKFYGECPYSNYLRKIIN 288


>UniRef50_Q01T68 Nucleotidyl transferase n=8 Tax=cellular organisms
           RepID=Q01T68_SOLUE
          Length = 257

 Score =  211 bits (538), Expect = 2e-53,   Method: Compositional matrix adjust.
 Identities = 111/238 (46%), Positives = 151/238 (63%), Gaps = 5/238 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG++LAGG+G+RL P+T+  +K LLPIYD+PMIYYP+  L+ AGI+EILI+T   + G 
Sbjct: 1   MKGVVLAGGTGSRLFPLTKITNKHLLPIYDRPMIYYPIQTLVDAGIQEILIVTGGRNSGD 60

Query: 61  FQRLLGDGSEFGIQ-LEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK 119
           F RLL +G +FG++ + Y  Q    G+A A  + E F +G   C+VLGDNI  G      
Sbjct: 61  FLRLLANGKQFGLKHINYTYQEGEGGIADALALAEHFADGHQICVVLGDNIIEGN-IKAA 119

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSK 179
                A+  GA +   +V D ERFGV E   + R + +EEKP  PKSN+AVTG+Y YD+ 
Sbjct: 120 ADRFRAQPAGAHILLKEVQDAERFGVAEVAGD-RIVGIEEKPNNPKSNYAVTGIYMYDAS 178

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
           V +  K + PS RGELEIT +N  Y+  GN++   L  G+ W D GT DSL+ A+  V
Sbjct: 179 VFQKIKTLVPSGRGELEITDVNNAYIREGNMSFSYL-DGW-WTDAGTFDSLLRATNLV 234


>UniRef50_B9KYJ6 Glucose-1-phosphate thymidylyltransferase n=5 Tax=cellular
           organisms RepID=B9KYJ6_THERP
          Length = 258

 Score =  203 bits (517), Expect = 5e-51,   Method: Compositional matrix adjust.
 Identities = 118/251 (47%), Positives = 161/251 (64%), Gaps = 14/251 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG++LAGG GTRL+P+T   +K LLP+YD+PMIYYP+  L+ AGI EI+++T     G 
Sbjct: 1   MKGVVLAGGLGTRLYPLTFATNKHLLPVYDQPMIYYPIQTLVKAGIDEIMVVTGGPHAGD 60

Query: 61  FQRLLGDGSEFGI-QLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK 119
           F R+L +G   G+  LEYA Q    G+A A  + E F +GE  C++LGDN        P 
Sbjct: 61  FLRVLRNGRHLGVRHLEYAYQEEERGIADALSLCEEFADGEHICVILGDNT-TDADIRPA 119

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDN--FRAISLEEKPKQPKSNWAVTGLYFYD 177
              V + T GA +F  +V DP RFG   FD N   R + +EEKPK+PKS +AVTGLY YD
Sbjct: 120 ---VESFTGGALIFLARVPDPHRFGCPVFDPNDPTRILRIEEKPKEPKSPYAVTGLYLYD 176

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLT-VELLGRGFAWLDTGTHDSLIEASTF 236
           ++V E+ ++++PS RGELEIT +N  YLE G L  VEL  +GF W D GT +SL  A+ +
Sbjct: 177 NRVFEFIRELEPSPRGELEITDVNNRYLELGLLRWVEL--QGF-WSDAGTFESLHRANRY 233

Query: 237 VQTVEKRQGFK 247
                +R+G++
Sbjct: 234 WA---ERRGYR 241


>UniRef50_A8FIL3 Spore coat polysaccharide biosynthesis protein SpsI n=7
           Tax=cellular organisms RepID=A8FIL3_BACP2
          Length = 246

 Score =  203 bits (517), Expect = 5e-51,   Method: Compositional matrix adjust.
 Identities = 105/249 (42%), Positives = 162/249 (65%), Gaps = 5/249 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+ILAGG G+RL P+T+  +K LLP+   PMIY+ L  L  AGI ++++I+  E    
Sbjct: 1   MKGVILAGGKGSRLAPLTKIFNKHLLPVGPYPMIYWSLFKLKEAGILDVMVISQAEQIPL 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           FQ+LL    E G+ + Y  QP   G++      + F+ GE   L+LGDN+ F    SP +
Sbjct: 61  FQKLLEGDQELGMNIVYQVQPEASGISDGLSYAKPFVEGEKFVLMLGDNV-FEDSLSPFV 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDD-NFRAISLEEKPKQPKSNWAVTGLYFYDSK 179
                +  GA V   +V DP+RFG+ E D  + R +S+EEKP+ P+S++ VTG+YFYD +
Sbjct: 120 DAFQRQESGAKVLLKEVTDPKRFGIAEIDAVHQRIVSIEEKPEHPRSSYCVTGIYFYDQE 179

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAST-FVQ 238
           V +Y +++ PS+RGELEIT +N +Y+    LT ++L +G+ W+D GTH+SL +AST   +
Sbjct: 180 VFQYIEKISPSDRGELEITDVNNLYISNSQLTYDML-KGW-WIDAGTHESLHQASTKMFE 237

Query: 239 TVEKRQGFK 247
           T++K++G++
Sbjct: 238 TMKKKEGYE 246


>UniRef50_P39629 Spore coat polysaccharide biosynthesis protein spsI n=88
           Tax=cellular organisms RepID=SPSI_BACSU
          Length = 246

 Score =  203 bits (516), Expect = 6e-51,   Method: Compositional matrix adjust.
 Identities = 111/249 (44%), Positives = 156/249 (62%), Gaps = 5/249 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+ILAGG+G+RL P+T+ V+K LLP+   PMIY+ +  L  AGI++IL+I+  E    
Sbjct: 1   MKGVILAGGNGSRLMPLTKAVNKHLLPVGPYPMIYWSIMKLQEAGIKDILLISQKEHMPQ 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F +LLG+G E G+ + Y  QP+  G++      + F   E   L+LGDNI F     P  
Sbjct: 61  FYKLLGNGEELGVTITYQVQPAASGISDGLSYAKRFTKKESFILLLGDNI-FEDSLKPYT 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDD-NFRAISLEEKPKQPKSNWAVTGLYFYDSK 179
                + +GA V   +V DPERFG+ E D+ N R  S+ EKP+QP +N  VTG+Y YD++
Sbjct: 120 ERFEQQGKGAKVLLKEVDDPERFGIAEIDEKNKRIRSIIEKPEQPPTNLCVTGIYMYDAE 179

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV-Q 238
           V  Y +Q+ PS+RGELEIT +N +Y+E   LT ++L  G+ W+D GTH+SL  AS  V Q
Sbjct: 180 VFSYIEQISPSKRGELEITDVNNLYIENSQLTYDVLS-GW-WVDAGTHESLYLASQLVHQ 237

Query: 239 TVEKRQGFK 247
            + K Q  K
Sbjct: 238 ALRKGQDEK 246


>UniRef50_Q8CUH8 Spore coat polysaccharide synthesis (Glucose-1-phosphate
           thymidyltransferase) n=1 Tax=Oceanobacillus iheyensis
           RepID=Q8CUH8_OCEIH
          Length = 239

 Score =  199 bits (505), Expect = 1e-49,   Method: Compositional matrix adjust.
 Identities = 99/238 (41%), Positives = 148/238 (62%), Gaps = 4/238 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+ILA G GTRLHP+T+ ++K L+PI   PMIYYP+  L    I EILI T  +D   
Sbjct: 1   MKGMILARGKGTRLHPLTKVINKHLIPIGKYPMIYYPIFKLREVDITEILITTNQQDIPL 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F+ LLGDG + G+++ +  Q    G+  A ++ +TF+  +   ++LGDNIF      P +
Sbjct: 61  FRELLGDGRDLGVRIHFEAQQQAIGIPDAILLSKTFVGSDKLTVILGDNIFH-DSLIPYV 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAI-SLEEKPKQPKSNWAVTGLYFYDSK 179
           +    ++ GA +    V DP R+G+  FD + + I S+EEKP    SN+ VTG+Y Y ++
Sbjct: 120 QSYEKQSTGAKILLKTVSDPNRYGIATFDKSQKNILSIEEKPSDSSSNYCVTGIYMYGTE 179

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
           V E+ KQ+ PS RGELEIT +N +YL+   LT ++L     W+D GT+DS+ +A+  +
Sbjct: 180 VFEFIKQITPSSRGELEITDVNNLYLQKSKLTFDVLPNW--WIDAGTYDSIFQANQII 235


>UniRef50_C7U1N1 RmlA protein n=1 Tax=Rhodococcus aetherivorans RepID=C7U1N1_9NOCA
          Length = 292

 Score =  183 bits (464), Expect = 8e-45,   Method: Compositional matrix adjust.
 Identities = 85/143 (59%), Positives = 110/143 (76%)

Query: 144 GVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQM 203
           G +EFD   RA+SLEEKP  PKSN+AV GLYFYD+ VV  A+ ++PS+RGE EIT IN+ 
Sbjct: 145 GXIEFDSEGRALSLEEKPATPKSNFAVPGLYFYDNDVVAIARGLRPSDRGEYEITDINRT 204

Query: 204 YLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEKRQGFKIACLEEIAWRNGWLDD 263
           YLEAG L VE+L RG AWLDTGT DSL++A  +V+T+E+RQG KI   EE+AWR G++ D
Sbjct: 205 YLEAGRLQVEVLPRGTAWLDTGTFDSLLDAGNYVRTIEQRQGLKIGAPEEVAWRRGFITD 264

Query: 264 EGVKRAASSLAKTGYGQYLLELL 286
           + ++  A+ L K+GYG YLL+LL
Sbjct: 265 DDLRALAAPLVKSGYGSYLLDLL 287



 Score = 43.5 bits (101), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 19/24 (79%), Positives = 23/24 (95%)

Query: 1  MKGIILAGGSGTRLHPITRGVSKQ 24
          M+GIILAGG+G+RLHPIT GVS+Q
Sbjct: 1  MRGIILAGGTGSRLHPITLGVSEQ 24


>UniRef50_Q55689 Glucose-1-phosphate thymidylyltransferase n=52 Tax=cellular
           organisms RepID=Q55689_SYNY3
          Length = 393

 Score =  164 bits (414), Expect = 5e-39,   Method: Compositional matrix adjust.
 Identities = 91/237 (38%), Positives = 134/237 (56%), Gaps = 2/237 (0%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +IL+GG GTRL P+T   +KQL+P+ +KP+++Y +  +  AGI +I II +PE    
Sbjct: 29  MKALILSGGKGTRLRPLTYTGAKQLVPVANKPILWYGIEAIAKAGITDIGIIISPETGEE 88

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            + + G+G +FGIQ+ Y  Q  P GLA A      FL   P  + LGDN+         L
Sbjct: 89  IKTITGNGEKFGIQITYILQSEPLGLAHAVKTAADFLQDSPFVMYLGDNLIQDH-LEQFL 147

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
            H  A++  + +   +V +P  FGV   +D  + ++L EKP+ P SN A+ GLYF+   +
Sbjct: 148 AHFQAKSLDSLILLRRVSNPSAFGVATVNDQGKVLALVEKPEHPPSNLALVGLYFFAPTI 207

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
            +    ++PS RGELEIT   Q YL + +  VE L     WLDTG  D L+ A+  +
Sbjct: 208 HQAIANIEPSARGELEITDAIQ-YLISHDYRVESLQLKGWWLDTGKKDDLLAANQII 263


>UniRef50_A7HN10 Glucose-1-phosphate thymidyltransferase n=9 Tax=cellular organisms
           RepID=A7HN10_FERNB
          Length = 376

 Score =  163 bits (412), Expect = 8e-39,   Method: Compositional matrix adjust.
 Identities = 93/236 (39%), Positives = 136/236 (57%), Gaps = 6/236 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK IIL  G GTRL P+T   +K L+P+ +KP+I Y +  +   GI++I II +PE+K  
Sbjct: 18  MKAIILCAGKGTRLRPLTYTTAKHLIPVANKPVILYTIEKIKSVGIKQIGIIVSPENKAD 77

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F+  LGDGS++G+++ Y  QP P GLA A ++ + FL  E   + LGDN+       P +
Sbjct: 78  FEENLGDGSKYGVEITYILQPEPKGLAHAVLMAKDFLGDEDFMMYLGDNLIM-DDIRPFV 136

Query: 121 RHVAARTE-GATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSK 179
                R    A +    V DP RFG+   + N R +   EKPK+P SN A+ GLY +   
Sbjct: 137 DEFEQRKNISALIMLSPVNDPTRFGIAVMEGN-RIVKTVEKPKEPPSNLAIIGLYLFRKD 195

Query: 180 VVEYAKQVKPSERGELEIT-SINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
           + E    +KPS RGELEIT +I+ +    GN+   ++  G+ W DTG  + L+EA+
Sbjct: 196 IFEGIANIKPSWRGELEITDAIDWLIQNKGNVEGHII-YGW-WKDTGKPEDLLEAN 249


>UniRef50_C7NU65 Glucose-1-phosphate thymidyltransferase n=5 Tax=Euryarchaeota
           RepID=C7NU65_HALUD
          Length = 357

 Score =  157 bits (397), Expect = 5e-37,   Method: Compositional matrix adjust.
 Identities = 95/258 (36%), Positives = 142/258 (55%), Gaps = 3/258 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG++LAGG+G+RL PIT    KQLLP+ +KP++ Y +  L  AGI +I ++   + +  
Sbjct: 1   MKGVLLAGGTGSRLRPITHTGPKQLLPVANKPVLEYAVEDLKDAGITDIGVVLGHKGREA 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            Q LLGDGSE+G+ + Y  Q +P GLA A      F+  +   + LGDNI   QG    +
Sbjct: 61  IQELLGDGSEYGVDITYIVQGNPLGLAHAAGCARDFVGDDDFVMYLGDNILK-QGIEDLV 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
               A   GA +   +V +P  FG+ E D +     L EKP  P SN A+ G+Y + + V
Sbjct: 120 ESFQAGEYGAGIALQEVQNPSEFGIAETDADGAVTRLVEKPADPPSNRALIGIYVFSNDV 179

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV-QT 239
            +  ++++PS RGELEIT   Q  LE GN     +  G+ W DTG    +++A+  V + 
Sbjct: 180 FDVIEELEPSWRGELEITDAIQDLLEEGNPIDSHVVEGW-WKDTGRPQDILDANRLVLED 238

Query: 240 VEKRQGFKIACLEEIAWR 257
           V   +  +I+   E+  R
Sbjct: 239 VADDRAGEISTDAEVTGR 256


>UniRef50_A5D3D6 dTDP-glucose pyrophosphorylase n=5 Tax=Bacteria RepID=A5D3D6_PELTS
          Length = 388

 Score =  156 bits (395), Expect = 7e-37,   Method: Compositional matrix adjust.
 Identities = 89/237 (37%), Positives = 131/237 (55%), Gaps = 2/237 (0%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +K +IL+GG GTRL P+T   +KQL+P+ +KP++ + +  +  AGIR+I +I +PE    
Sbjct: 34  VKALILSGGKGTRLRPLTYTTAKQLIPVANKPILEFVVEQICQAGIRDIGMIISPETGEQ 93

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  +G G  +G ++ Y  Q  P GLA A      FL   P  + LGDN+  G G    +
Sbjct: 94  VKEAIGCGERWGARITYILQEKPAGLAHAVKTARPFLGDSPFLMFLGDNLVQG-GVGQLV 152

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           +  A     A +   +V DP +FGV    +N R I L EKPK+P  N A+ G+Y + S V
Sbjct: 153 KDFAGSRADAMIQLKEVADPSQFGVAVLGENNRVIRLVEKPKEPPGNLALVGIYLFGSAV 212

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
               +++KPS RGELEIT   Q  +  G      +  G+ WLDTG  D ++EA+  V
Sbjct: 213 HRAIERIKPSWRGELEITDAIQEMINLGCSVDARILDGW-WLDTGKKDDILEANRVV 268


>UniRef50_UPI000038E60D glucose-1-phosphate thymidylyltransferase (graD-2) n=1
           Tax=Ferroplasma acidarmanus fer1 RepID=UPI000038E60D
          Length = 351

 Score =  156 bits (395), Expect = 7e-37,   Method: Compositional matrix adjust.
 Identities = 100/260 (38%), Positives = 150/260 (57%), Gaps = 25/260 (9%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILII---TTPED 57
           MKGIIL GG+GTRL P+T    KQL+PI +KPM  Y L  L  AGI +I +I    +PE 
Sbjct: 1   MKGIILHGGAGTRLRPLTHTGPKQLIPIANKPMSQYVLEYLTDAGINDICMILGDISPEK 60

Query: 58  -KGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGF 116
            K Y+    GDGSEF   ++Y +Q +P G+A A  +   F+  +   ++LGDN+  G   
Sbjct: 61  VKDYY----GDGSEFDCNIQYIDQGAPLGIANAVSLTSNFVGNDKFVVILGDNLIEG--- 113

Query: 117 SPKLRHVAARTEGATVFGYQV----MDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTG 172
             K++    + E +    + V    M P+ FGV EF DN + I+L EKP+ P SN+ +TG
Sbjct: 114 --KIKTFMDKFEKSNYDAFIVLTKSMHPKDFGVAEFRDN-KLINLIEKPENPPSNYVLTG 170

Query: 173 LYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAG-NLTVELLGRGFAWLDTGTHDSLI 231
           +YF+   + +Y K++KPS R E EIT   Q+ L+   N+  +++  G+ W DTGT D ++
Sbjct: 171 IYFFTPLIFDYIKKLKPSWRNEYEITEAIQLLLKDNKNIGYDII-DGW-WKDTGTVDDIL 228

Query: 232 EASTFV----QTVEKRQGFK 247
            A+  +    + +E+R   K
Sbjct: 229 AANMLILDRGKNIEERANVK 248


>UniRef50_P08075 Glucose-1-phosphate thymidylyltransferase n=49 Tax=Bacteria
           RepID=STRD_STRGR
          Length = 355

 Score =  154 bits (390), Expect = 3e-36,   Method: Compositional matrix adjust.
 Identities = 89/244 (36%), Positives = 132/244 (54%), Gaps = 4/244 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++LAGG+GTRL PIT   +KQL+P+ +KP+++Y L  +  AGI ++ I+   +    
Sbjct: 1   MKALVLAGGTGTRLRPITHTSAKQLVPVANKPVLFYGLEAIRAAGIIDVGIVVG-DTADE 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
               +GDGS FG+++ Y  Q  P GLA   +I   FL  +   + LGDN   G      +
Sbjct: 60  IVAAVGDGSRFGLKVSYIPQSKPLGLAHCVLISRDFLGEDDFIMYLGDNFVVGV-VEDSV 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           R   A    A +   +V +P  FGV E  D+ + + LEEKP  PKS+ A+ G+Y +   +
Sbjct: 119 REFRAARPDAHLMLTRVPEPRSFGVAELSDSGQVLGLEEKPAHPKSDLALVGVYLFSPAI 178

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV-QT 239
            E    + PS RGELEIT   Q  ++AG      +  G+ W DTG    ++E +  V +T
Sbjct: 179 HEAVAAITPSWRGELEITDAVQWLIDAGRDVRSTVISGY-WKDTGNVTDMLEVNRLVLET 237

Query: 240 VEKR 243
            E R
Sbjct: 238 TEPR 241


>UniRef50_A7GF11 Glucose-1-phosphate thymidylyltransferase n=9 Tax=Clostridium
           botulinum RepID=A7GF11_CLOBL
          Length = 353

 Score =  146 bits (369), Expect = 8e-34,   Method: Compositional matrix adjust.
 Identities = 83/237 (35%), Positives = 137/237 (57%), Gaps = 4/237 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +IL+GG+GTRL P+T   +KQLLP+ +KP+++Y +  ++ AGI +I II   + +  
Sbjct: 1   MKALILSGGTGTRLRPLTYTNAKQLLPLANKPILFYIIEKIVKAGIYDIGIIVG-DTREE 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            ++++G+G  +G+++ Y  QP+P GLA A      FL  +   +VLGDN+ F    +  +
Sbjct: 60  VKKMVGNGDRWGVKISYLYQPAPLGLAHAVKTASEFLMEDDFLMVLGDNV-FNMELNKLI 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
               +    + +  ++V +P ++GV   +D    I L EKPK+  S+  +TG+Y +D  +
Sbjct: 119 DSFYSNNANSALLLHKVENPSQYGVAVVEDTL-IIKLVEKPKEFVSDLIITGVYIFDKSI 177

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
                 +KPS+RGELEIT   Q  LE G      L +G+ W DTG    ++EA+  +
Sbjct: 178 FMAIDNIKPSQRGELEITDAIQKQLETGGRVTYELIQGW-WKDTGQLQDILEANRLM 233


>UniRef50_C0ZCI7 Probable glucose-1-phosphate thymidylyltransferase n=1
           Tax=Brevibacillus brevis NBRC 100599 RepID=C0ZCI7_BREBN
          Length = 348

 Score =  146 bits (368), Expect = 1e-33,   Method: Compositional matrix adjust.
 Identities = 86/241 (35%), Positives = 130/241 (53%), Gaps = 4/241 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+IL  G GTRLHP +    K LLP+ + P+++Y +  L   GI++I I+  P  +  
Sbjct: 1   MKGLILCAGRGTRLHPFSYSQPKTLLPVANHPVLHYCIRKLREVGIQDIGIVIHPS-QSQ 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
              ++GDGS+FG  + + +Q  P G+A A  + + FL  EP  L+LGDN+          
Sbjct: 60  IPPMVGDGSQFGATITFIKQEVPLGIAHAVQLAQPFLQDEPFILLLGDNLLMDSLHGLTK 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                +++G  +   +V  P+ +G+ E     R IS+EEKP+QPKSN AV G Y +   +
Sbjct: 120 AFTKGKSDGVVMLS-KVERPQDYGIAEVQKG-RLISVEEKPRQPKSNLAVIGAYLFTPPI 177

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            E    ++PS RGELEIT   Q  +  G      +  G  + D GT D  +EA+ ++ T 
Sbjct: 178 FESIATLQPSPRGELEITDAIQSMINRGFKLAHSVTNG-KYSDVGTIDRWLEANQWMLTR 236

Query: 241 E 241
           E
Sbjct: 237 E 237


>UniRef50_A4YHT6 Glucose-1-phosphate thymidyltransferase n=1 Tax=Metallosphaera
           sedula DSM 5348 RepID=A4YHT6_METS5
          Length = 349

 Score =  145 bits (367), Expect = 1e-33,   Method: Compositional matrix adjust.
 Identities = 93/237 (39%), Positives = 133/237 (56%), Gaps = 8/237 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+ILAGG GTRL P+T   +K  +PI +KPM+ Y +  L+ AGIR+I++I  P  +G 
Sbjct: 1   MKGLILAGGHGTRLRPLTHTGNKHAIPIANKPMVLYAVENLVNAGIRDIVVILGPLKEGI 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            + + G+   +     Y EQ  P GLA A +  E +L+ EP  + LGDN     G S  +
Sbjct: 61  KEAIDGN---YPANFTYVEQ-EPLGLAHAVMKAEKYLD-EPFVMHLGDN-LLQNGISQFV 114

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                    A +    V DP ++GVV   +N R   L EKP+ P SN A+ G+Y +   V
Sbjct: 115 NKFHETKADAVIGVTPVKDPRQYGVVVI-ENGRVKRLMEKPRDPPSNLALVGVYVFTPVV 173

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
            +Y K++KPS RGE EIT + Q+ +E G   VE++     W DTG  + L+EA+  V
Sbjct: 174 HDYTKRLKPSWRGEYEITDVLQLMVEDGR-RVEVVQVEGWWKDTGKPEDLLEANQLV 229


>UniRef50_B5GLJ2 NDP-1-glucose synthase n=1 Tax=Streptomyces clavuligerus ATCC 27064
           RepID=B5GLJ2_STRCL
          Length = 359

 Score =  145 bits (366), Expect = 2e-33,   Method: Compositional matrix adjust.
 Identities = 92/238 (38%), Positives = 127/238 (53%), Gaps = 5/238 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREI-LIITTPEDKG 59
           MK ++LAGGSG+RL P++  + KQL+P+ +KP++ Y L  +   GI  I L++    D  
Sbjct: 1   MKALVLAGGSGSRLRPLSNFMPKQLIPVANKPVLEYVLENIRELGITRIGLVVGGWADT- 59

Query: 60  YFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK 119
             +  +GDGS FG ++ Y  Q  P GLA A  +   FL  +   + LGDN+    G +P 
Sbjct: 60  -IRGAVGDGSRFGAEITYLRQERPAGLAHAVRLARPFLGDDDFAMFLGDNLLP-DGVAPV 117

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSK 179
                     A V  ++V DP  FGVVE D       L EKP +P+S+ A+ G YF+ S 
Sbjct: 118 AADFLRGRPAAQVVVHKVDDPRDFGVVELDAAGGVRRLVEKPSRPRSDLALVGTYFFTSA 177

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
           V      ++PS RGELEIT   Q  LE G  +V     G  W DTG  D L+EA+  V
Sbjct: 178 VHRAVDAIRPSPRGELEITDAIQWLLEDGA-SVGCSEYGGYWKDTGRADDLLEANRRV 234


>UniRef50_O29921 Glucose-1-phosphate thymidylyltransferase (GraD-2) n=1
           Tax=Archaeoglobus fulgidus RepID=O29921_ARCFU
          Length = 352

 Score =  144 bits (362), Expect = 4e-33,   Method: Compositional matrix adjust.
 Identities = 89/240 (37%), Positives = 132/240 (55%), Gaps = 9/240 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILII---TTPED 57
           MKG++L GG+GTRL P+T    KQL+P+ +KP+  Y L  ++ AGI+E+ II   T PE 
Sbjct: 1   MKGVLLHGGAGTRLRPLTFTGPKQLIPVANKPVSQYCLEDMIGAGIKEVAIILGETYPE- 59

Query: 58  KGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
               +   GDGS FG ++ Y  Q  P G+A A  + + F+  E   + LGDN+    G  
Sbjct: 60  --MVEEHYGDGSRFGCKITYIHQGKPLGIAHAVYLAKDFVGDEKFVVYLGDNL-IQDGIK 116

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYD 177
             ++        A +   +V DP  FGV +F+   R + L EKPK+P SN+AV G+Y + 
Sbjct: 117 EYVKRFDEEDFDAFILLKEVEDPRAFGVAKFEGE-RLVGLIEKPKEPPSNYAVIGVYMFK 175

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
             V +  K +KPS RGELEIT   Q  +E G        +G+ W DTG  + +++ +  +
Sbjct: 176 PVVFDIIKDLKPSWRGELEITDTLQKMIENGYNVGYAKLKGW-WFDTGKAEDILKVNATI 234


>UniRef50_A9A1Q3 Glucose-1-phosphate thymidyltransferase n=1 Tax=Nitrosopumilus
           maritimus SCM1 RepID=A9A1Q3_NITMS
          Length = 351

 Score =  140 bits (354), Expect = 4e-32,   Method: Compositional matrix adjust.
 Identities = 89/234 (38%), Positives = 131/234 (55%), Gaps = 3/234 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKGIIL GG GTRL P+T    KQLLPI +KPM  Y +  +  AGI EI II        
Sbjct: 1   MKGIILHGGHGTRLRPLTHTGPKQLLPIANKPMSQYCIESMKNAGITEIAIIIGGIASKK 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   G+G +FG+++ Y  Q +P G+A A  + + F+  +   + LGDNI   +    K 
Sbjct: 61  VEEYYGNGEKFGVKITYISQEAPKGIAHAINLCKDFVKDDKFLVFLGDNILKKEILEYKT 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
            +  +  + A +   +V +P +FG+ +  DN + I + EKPK P +N AVTG+YF + K+
Sbjct: 121 NYENSDAD-ALLLLCEVDNPTQFGIADVKDN-KIIKIMEKPKDPPTNLAVTGIYFLNKKI 178

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
            E    +KPS R ELEIT   Q+ +E GN  +      + W DTGT + ++ A+
Sbjct: 179 FEIIDILKPSWRNELEITDALQLLMEKGNKIIFDTVTDY-WKDTGTPNDILHAN 231


>UniRef50_Q97A91 Glucose-1-phosphate thymidylyltransferase n=2 Tax=Thermoplasma
           volcanium RepID=Q97A91_THEVO
          Length = 351

 Score =  136 bits (342), Expect = 1e-30,   Method: Compositional matrix adjust.
 Identities = 87/238 (36%), Positives = 123/238 (51%), Gaps = 5/238 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKGIIL GGSGTRL P+T    KQLLPI  KP+  Y L  L+  GI+ I I+        
Sbjct: 3   MKGIILHGGSGTRLRPLTYTDVKQLLPIAGKPISEYALENLIEIGIKNINIVIGSVGGLE 62

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            ++  GDGS + + + Y  QP P G+A A  + + F+  +   + LGDN +   G S   
Sbjct: 63  VKKFYGDGSRWNVNISYTYQPEPLGIAHAIGLTKAFVGNDDFVVFLGDN-YLQNGISNLY 121

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                      +    V +P +FG+ E D N +   L EKPK P SN A+ G+YF   KV
Sbjct: 122 EDFTNAGSDGHLGLVPVDNPSQFGIAEVD-NGKISKLVEKPKTPTSNLAIVGVYFLTPKV 180

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAG-NLTVELLGRGFAWLDTGTHDSLIEASTFV 237
            E   ++KPS+RGE EIT   Q  ++ G  ++  ++   F   DTGT D  +  +  +
Sbjct: 181 FESIDRLKPSKRGEYEITEAYQDMIDRGLKISYSIISGWFK--DTGTVDDFLACNRLI 236


>UniRef50_C6D3B0 Nucleotidyl transferase n=1 Tax=Paenibacillus sp. JDR-2
           RepID=C6D3B0_PAESJ
          Length = 330

 Score =  135 bits (340), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 89/253 (35%), Positives = 130/253 (51%), Gaps = 21/253 (8%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+IL  G G+RL+P T+   K L+P+ + P++   +  LM  GI  I I+  P  +  
Sbjct: 1   MKGLILCAGKGSRLYPFTKNRPKTLIPVTNTPLLQLSIMKLMELGIDRIGIVIHPSQEAD 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   G+G  FGI + Y  Q +P G+A A    E +L+GEP  L+LGDN+      S  L
Sbjct: 61  IRAQFGEGEAFGISITYIYQHAPKGIANALKNAEYYLSGEPFLLLLGDNL-----ISAPL 115

Query: 121 RHVAARTEG----ATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFY 176
             +    E     A++   +V DP+ +G+ E  D+ R I LEEKP  PKSN AV G Y +
Sbjct: 116 SDLKYDVEHGGVQASLLLAEVADPQDYGIAEIQDS-RIIGLEEKPVHPKSNLAVIGGYAF 174

Query: 177 DSKVVEYAKQVKPSERGELEITS-----INQMYLEAGNLTVELLGRGFAWLDTGTHDSLI 231
             ++     ++ PS+RGE EIT      I Q Y  A  +T +L       +D GT D  +
Sbjct: 175 TKEIFGAVNKITPSKRGEYEITDAIQWLIEQRYDVAYRVTDQL------NIDVGTKDRWL 228

Query: 232 EASTFVQTVEKRQ 244
            A+  +   E  Q
Sbjct: 229 LANRKLLEAEALQ 241


>UniRef50_B0BLL5 dTDP-1-glucose synthase n=1 Tax=Actinomadura madurae
           RepID=B0BLL5_9ACTO
          Length = 344

 Score =  131 bits (330), Expect = 3e-29,   Method: Compositional matrix adjust.
 Identities = 75/225 (33%), Positives = 114/225 (50%), Gaps = 3/225 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++LAGG+ +RL P +  + KQL+P+  +P++ + L  +   G+R+  I+        
Sbjct: 1   MKALVLAGGTASRLRPFSNSLPKQLIPLAGRPVLEHVLRGIADIGVRDTAIVVGDTAPAV 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
               +GDG+  G+++ Y  Q  P GLA    +   FL  +   + LGDN+  G G +   
Sbjct: 61  MD-AIGDGARLGLRVTYVPQARPLGLAHCVTLARPFLGDDDFVMYLGDNLLPG-GIAGPA 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           R    R   A +   +V DP  FGV E   +     LEEKP  P+++ AV G+YF+ S V
Sbjct: 119 RRFRDRRPSAQLLLRRVADPRAFGVAEVGRDGVVRRLEEKPAHPRTDLAVLGVYFFTSAV 178

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTG 225
                  +PS RGELEIT   Q+ ++ G  TV  +     W D G
Sbjct: 179 HAAIDACRPSHRGELEITDAIQVLIDRGR-TVRAVEHTGHWRDIG 222


>UniRef50_A8LZU8 Glucose-1-phosphate thymidyltransferase n=15 Tax=Actinomycetales
           RepID=A8LZU8_SALAI
          Length = 353

 Score =  130 bits (327), Expect = 5e-29,   Method: Compositional matrix adjust.
 Identities = 78/239 (32%), Positives = 124/239 (51%), Gaps = 3/239 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++L+GG GTRL P T  + KQL P+ ++P++ + L  +   G+ E+ I+        
Sbjct: 1   MKALVLSGGMGTRLRPFTHSMPKQLFPVANQPVLAHVLGKIRTLGVTEVGIVVGGGGAAQ 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  +GDG+ FG+Q+ Y  Q  P GLA A  +   FL  +   + LGDN+   +G    +
Sbjct: 61  VEEAIGDGARFGLQVTYVHQHQPRGLAHAVQVAADFLGTDDFLVYLGDNVLT-EGLVEFV 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                    A +   +V DP  +GVVE D   R   L EKP  P+S+ A+ G+Y +  ++
Sbjct: 120 ARFRDERPAAHLLVQKVSDPRSYGVVELDAG-RVQRLVEKPASPRSDLAIVGVYLFTHEI 178

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
               ++++P  RGELE+T   Q  +++G   VE    G  W D G  D L+E +  + T
Sbjct: 179 HTAIREIRPGRRGELELTDAVQWLVDSGA-RVEATEYGGNWSDVGQVDDLLECNRHLLT 236


>UniRef50_Q46AY8 Glucose-1-phosphate thymidylyltransferase n=4
           Tax=Methanosarcinaceae RepID=Q46AY8_METBF
          Length = 397

 Score =  124 bits (310), Expect = 5e-27,   Method: Compositional matrix adjust.
 Identities = 80/256 (31%), Positives = 138/256 (53%), Gaps = 25/256 (9%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++L  G GTR+ P+T G  K +L + +KP++ + L+  + AGI   + IT     GY
Sbjct: 1   MKAVVLVAGKGTRMEPLTSGCPKVMLQVANKPILEHILNSAIEAGIEGFVFIT-----GY 55

Query: 61  FQRLL----GDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGF 116
            ++ +    GDG+++G+ +EY +Q    G A A    + +++G  + LVL  ++   Q  
Sbjct: 56  LEKQIKEYFGDGNKWGVSIEYVQQKEQLGTANAIGCAKGYVDG--TFLVLNGDMLIEQ-- 111

Query: 117 SPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFY 176
              L+ + +RTE A +   +V +P  FGV+E ++N R + + EKPK P +N A  G+Y +
Sbjct: 112 -EDLKALVSRTEEAVICVKEVENPADFGVLETENN-RVVRIIEKPKNPPTNLANAGIYLF 169

Query: 177 DSKVVEYAKQVKPSERGELEITSINQMYLEAGNLT--VELLGRGFAWLDTGTHDSLIEAS 234
              + ++  + K S R E EIT   QM +++G       L GR   W+D G    L++A+
Sbjct: 170 RESIFDFIDRTKASVRNEFEITDSIQMLIDSGTAVGYSPLEGR---WIDIGYPWDLLKAN 226

Query: 235 TFVQTVEKRQGFKIAC 250
            ++      +G K +C
Sbjct: 227 EYLL-----KGLKSSC 237


>UniRef50_UPI0001693120 glucose-1-phosphate thymidyltransferase n=1 Tax=Paenibacillus
           larvae subsp. larvae BRL-230010 RepID=UPI0001693120
          Length = 338

 Score =  123 bits (309), Expect = 7e-27,   Method: Compositional matrix adjust.
 Identities = 78/248 (31%), Positives = 129/248 (52%), Gaps = 5/248 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+IL  G GTRL P T    K +LP+  +P+I   ++ ++  GI EI I+     +G 
Sbjct: 1   MKGLILCAGQGTRLQPFTYARPKCMLPVNGEPVIVSIINKMVHIGICEIGIVIN-ASQGQ 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
              +LG G  +   L Y  Q +  GLA A     +F+ GEP  L+LGDN+  G    P +
Sbjct: 60  IPAMLGSGEAYRCSLTYLLQENSLGLADAVKSAYSFIQGEPFLLILGDNLIEG-SIMPLI 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
             + +    A++    V +P +FGV +   N + + LEEK + P S+ AV G Y ++S +
Sbjct: 119 DFLGSEKADASLLLAHVKNPHQFGVADVSIN-KVVRLEEKSQNPSSDLAVVGAYAFNSDI 177

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTF-VQT 239
            +   +++PS+RGE E+T   Q+ ++ G      +     + D GT +  ++A+ + V  
Sbjct: 178 WKILDRLEPSKRGEYELTDAIQLLIDQGKHVAYCITTE-PFFDIGTPERWLDANRYKVSK 236

Query: 240 VEKRQGFK 247
             ++Q  K
Sbjct: 237 DSRKQNIK 244


>UniRef50_D2PJ00 Glucose-1-phosphate thymidyltransferase n=15 Tax=Archaea
           RepID=D2PJ00_SULIS
          Length = 346

 Score =  121 bits (304), Expect = 3e-26,   Method: Compositional matrix adjust.
 Identities = 81/237 (34%), Positives = 123/237 (51%), Gaps = 6/237 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +IL GG GTRL P+T    KQL+ I  KP+  + L  +  AGI++I+II    +   
Sbjct: 1   MQAVILHGGQGTRLRPLTHTGPKQLIKIAGKPVSQWVLEQIRDAGIKDIIIILGDNNPNK 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                G+GS FG+ + Y  Q    GLA A    +  +  +   + LGDNI         L
Sbjct: 61  VVEYYGEGSRFGVNVTYVYQGKARGLADAVYKVKDVITEDRFLVYLGDNIVPYDNLPSFL 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
               +    A++   +V +P RFGV    D  + I L EKPK+  S+ A+ G+Y +  ++
Sbjct: 121 SFKGS----ASILLAKVDNPNRFGVAIIKDG-KVIRLVEKPKEKISDSALVGVYAFTREI 175

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
            E  + +KPS RGELEIT   Q  ++ G      +  G+ W DTGT   ++EA++F+
Sbjct: 176 FEVIENLKPSWRGELEITDAIQGLIDRGREVEYKIIDGW-WKDTGTPKDILEANSFL 231


>UniRef50_Q1J1J1 Glucose-1-phosphate thymidyltransferase n=10 Tax=Deinococci
           RepID=Q1J1J1_DEIGD
          Length = 355

 Score =  120 bits (300), Expect = 7e-26,   Method: Compositional matrix adjust.
 Identities = 80/237 (33%), Positives = 115/237 (48%), Gaps = 5/237 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK II A G GTRL P+T    K +LP+   P+I + L  L+ AGI E+ II +   +  
Sbjct: 4   MKAIIPAAGLGTRLRPLTYTRPKPVLPVAGAPIIVHALRTLLAAGINEVGIIVSDATRAE 63

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
             + L    E  +Q+    Q    GL  A +    ++  +  C+ LGDN  F  G +P +
Sbjct: 64  IAQTLEQVPE--VQVTLINQHEQLGLGHAVLTARNWVGQQNFCVYLGDN-LFEHGVAPFI 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                    A +   +V DP  FGV E +   R   L EKPK P SN AV GLY +  +V
Sbjct: 121 ERFQREQAAAVIALVEVPDPTAFGVAELEGE-RITRLVEKPKVPPSNLAVAGLYCFTPEV 179

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
            +    + PS RGE EIT   Q  ++ G   +    +G+ W DTG    L++A+  +
Sbjct: 180 FDVLDGMPPSARGEYEITDAIQGLVDRGQTVLGQCVQGW-WKDTGRPADLLDANRLL 235


>UniRef50_A8A970 Nucleotidyl transferase n=1 Tax=Ignicoccus hospitalis KIN4/I
           RepID=A8A970_IGNH4
          Length = 355

 Score =  118 bits (296), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 91/253 (35%), Positives = 134/253 (52%), Gaps = 14/253 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+GIILA G G+RL P+T  V K L+P+  KP++ Y +  L   G+   +++     +  
Sbjct: 1   MEGIILAAGKGSRLRPLTLTVPKPLIPVAGKPLVQYGIEQLRGVGVERAVVVVGWLGE-L 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGE---PSCLVLGDNIFFGQGFS 117
           F+ +LGDGS  G++ EY  QP   G+A A  I    +N     P  +  GDN+F  + + 
Sbjct: 60  FKEVLGDGSALGMRFEYVLQPKRLGVAHA--IHTAIVNANVRSPFLVYFGDNVFDDE-WV 116

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLY-FY 176
            K   V    +   V   +V DP RFGV   +   R +   EKP++P SN+A+TGLY F 
Sbjct: 117 KKFNSVDEEFDAFVVLA-KVEDPRRFGVPVIESG-RIVKFVEKPERPPSNYALTGLYAFR 174

Query: 177 DSKVVEYA-KQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAST 235
           D +  E    ++KPS RGE EIT +   Y+  G      +  G+ W DTG  + LIEA  
Sbjct: 175 DPEQYESCFSELKPSWRGEYEITDLLNCYIRRGYDVKYAVVEGW-WKDTGVPEDLIEAMK 233

Query: 236 FVQTVEKRQGFKI 248
           F+  +EK+   K+
Sbjct: 234 FI--LEKKLIHKV 244


>UniRef50_Q1J1Y9 Nucleotidyl transferase n=2 Tax=Deinococcus RepID=Q1J1Y9_DEIGD
          Length = 365

 Score =  117 bits (294), Expect = 3e-25,   Method: Compositional matrix adjust.
 Identities = 75/234 (32%), Positives = 114/234 (48%), Gaps = 9/234 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+ILA G G+RL P++ G  K  +PI   P+I + +  +  AG+ E+ ++T+  ++  
Sbjct: 21  MKGVILAAGRGSRLFPVSAGRPKHAVPIAGVPIIAWAVRAVREAGVEEVAVVTSSNNEAA 80

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +    D       L +  Q  P G   A +    FL G P+ L LGDN+ F    +P  
Sbjct: 81  LREATRDEG----PLTFLRQEEPRGTGDAVLAARAFLEGSPALLYLGDNL-FADPLTPLT 135

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
              A +   A +   QV DP  +GV    DN    +L+EKP  P S+ A  G++ +   V
Sbjct: 136 E--ALQDADAALGVKQVPDPSAYGVAAVRDNL-LTNLDEKPAAPASDLAACGVFAFHPHV 192

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
           +E   +++PS RGE+E        + AG     +   GF W D GT   L+ AS
Sbjct: 193 LEEVARLEPSVRGEIEFPQALLRVIAAGGRVRAVTFPGF-WSDAGTPADLLSAS 245


>UniRef50_C8PNG7 Glucose-1-phosphate thymidylyltransferase n=1 Tax=Treponema
           vincentii ATCC 35580 RepID=C8PNG7_9SPIO
          Length = 106

 Score =  117 bits (293), Expect = 5e-25,   Method: Compositional matrix adjust.
 Identities = 56/98 (57%), Positives = 71/98 (72%), Gaps = 1/98 (1%)

Query: 185 KQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEKRQ 244
           K VKPS RGE+EITS+N  YL AG L VE LGRG AWLDTG++D L+EAS F+ T++KRQ
Sbjct: 3   KNVKPSARGEIEITSVNNAYLAAGKLKVEKLGRGMAWLDTGSYDGLLEASNFIATIQKRQ 62

Query: 245 GFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYL 282
           G  ++C+EEIA+   W+  E + + A    KT YGQYL
Sbjct: 63  GMYVSCIEEIAYLKRWITKEQLLKLAEGY-KTEYGQYL 99


>UniRef50_Q9YCT0 Glucose-1-phosphate thymidylyltransferase n=1 Tax=Aeropyrum pernix
           RepID=Q9YCT0_AERPE
          Length = 355

 Score =  115 bits (287), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 88/244 (36%), Positives = 131/244 (53%), Gaps = 23/244 (9%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +KG+ILA G G+RL P T    K L+P+  KP+I Y +  L+   +R+I ++      GY
Sbjct: 2   VKGLILAAGEGSRLRPFTFSRPKHLIPLLGKPIIQYAIDDLVSINVRDIGVVV-----GY 56

Query: 61  F----QRLLGDGSEFGIQLEYAEQPSPDGLAQAF--IIGETFLNGEPSCLVLGDNIFFGQ 114
           F    +  LG+ S FG +  Y  Q    G+A A    I + F++ E   + LGDNI  G 
Sbjct: 57  FGDKIKEFLGEDSRFGAKFTYIVQKKRLGIAHAIYRAIKQGFIDKE-FIVYLGDNILSG- 114

Query: 115 GFSPKLRHVAARTEGAT---VFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVT 171
           G S   RHV +  E  +   +   +V DP RFG+    D  + + L EKP++  S+ AV 
Sbjct: 115 GIS---RHVKSWGEAGSEVHILLTKVRDPGRFGIAVLRDG-KILKLVEKPQEHISDLAVV 170

Query: 172 GLY-FYDSKVVEYA-KQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDS 229
           G+Y F D ++V  A   +KPS RGE EIT + Q +++ G      L  G+ W D GT++ 
Sbjct: 171 GVYMFRDPELVAKAFSTLKPSWRGEYEITDLIQWFVDKGYKVTFSLVTGW-WKDVGTYEG 229

Query: 230 LIEA 233
           L++A
Sbjct: 230 LLDA 233


>UniRef50_UPI0001C418F3 UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate
           N-acetyltransferase GlmU n=1 Tax=Methanobrevibacter
           ruminantium M1 RepID=UPI0001C418F3
          Length = 439

 Score =  111 bits (278), Expect = 3e-23,   Method: Compositional matrix adjust.
 Identities = 82/243 (33%), Positives = 123/243 (50%), Gaps = 20/243 (8%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPED--- 57
           MK +IL+ G GTR+ P+T    K +LP+  KP+I Y +  L   G+++IL+I   ++   
Sbjct: 1   MKALILSAGEGTRMRPLTLTKPKTMLPVAGKPIIQYNIEALRECGVKDILLIVGYKEEMV 60

Query: 58  KGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
           K YF     DGS+FG+ + YA Q   +G A A   G+ F+  E S + L  +I   +   
Sbjct: 61  KNYFD----DGSKFGVNISYATQTKLEGTANAISYGKDFI--EDSLITLNGDIILDEEI- 113

Query: 118 PKLRHVAARTE--GATVFGY--QVMDPERFGVVEFDDNFRAISLEEKPKQPK--SNWAVT 171
             LR +    E  GA       +V DP  FGVVE D   +  ++ EKPK+ +  SN   T
Sbjct: 114 --LREIIEDYEESGADTLMVLTEVEDPSAFGVVELDGE-KITNIVEKPKKEEAPSNLVNT 170

Query: 172 GLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLI 231
           G+Y ++  + +   + K S RGE EIT    + +E G   V+       W+D G    LI
Sbjct: 171 GIYIFNKDIFDKIDKTKVSPRGEYEITDSLSLQIEDGKF-VKGHKTEKEWMDIGKPWELI 229

Query: 232 EAS 234
           E +
Sbjct: 230 EIN 232


>UniRef50_A3CRY9 UDP-glucose pyrophosphorylase n=2 Tax=Methanomicrobia
           RepID=A3CRY9_METMJ
          Length = 262

 Score =  108 bits (269), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 78/238 (32%), Positives = 119/238 (50%), Gaps = 11/238 (4%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           +G+I A GSG+RL P T  + K+LLP+ +K +I + +  + LAGI +I+I+ +P   G  
Sbjct: 5   QGLIPAAGSGSRLGPFTNAIPKELLPVGEKAVIEHVVEAMSLAGITDIVIVVSPHKHG-L 63

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL- 120
              LG G  FG+   Y  Q    GLA A   GE  ++G    +VLGDN F  + F   L 
Sbjct: 64  SDYLGSGKRFGVDFTYVVQDERLGLANAVAAGEHVIDGT-FAVVLGDNFFAPKTFLADLI 122

Query: 121 -RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPK---SNWAVTGLYFY 176
             H A R +  TV   +V D  R G++   D  R   + EKP QP    SN    G Y +
Sbjct: 123 GYHAAHRPD-TTVGVARVEDVTRHGII-LPDGDRVADMVEKP-QPTAAPSNLGALGAYVF 179

Query: 177 DSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
           ++ + +   + KP  +GE ++T   ++ +  G      +  G   +D GT   L+ A+
Sbjct: 180 ETSIFDAIARTKPGHKGEYQLTDAIRLEIAEGRDVRYRVIDGI-HIDVGTPRDLMRAN 236


>UniRef50_Q7BM20 STMD1.67 protein n=18 Tax=Gammaproteobacteria RepID=Q7BM20_SALTY
          Length = 74

 Score =  106 bits (264), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 49/58 (84%), Positives = 52/58 (89%)

Query: 236 FVQTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRARPRQY 293
             + V KRQGFKIACLEEIAWRNGWLDD+G+KRAAS L KTGYGQYLLELLRARPRQY
Sbjct: 17  ITRGVSKRQGFKIACLEEIAWRNGWLDDDGLKRAASQLEKTGYGQYLLELLRARPRQY 74



 Score = 49.7 bits (117), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 23/24 (95%), Positives = 24/24 (100%)

Query: 1  MKGIILAGGSGTRLHPITRGVSKQ 24
          MKGIILAGGSGTRLHPITRGVSK+
Sbjct: 1  MKGIILAGGSGTRLHPITRGVSKR 24


>UniRef50_Q048R4 Glucose-1-phosphate thymidylyltransferase n=2 Tax=Lactobacillus
           delbrueckii subsp. bulgaricus RepID=Q048R4_LACDB
          Length = 285

 Score =  105 bits (263), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 81/255 (31%), Positives = 114/255 (44%), Gaps = 23/255 (9%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+I+A G G R+ P T   SK    IYDKP ++Y L+ L+  GI +I I+ TPE    
Sbjct: 1   MKGVIIAAGFGKRIWPATEAYSKIFHQIYDKPTVFYNLTNLIAMGITDICIVGTPEMNRQ 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPD--GLAQAFIIGETFLNGEPSCLVLGDNIF--FGQGF 116
           F++L  D S     L + ++   D  G A +    E F+  +   L +GD +F       
Sbjct: 61  FKKLFSD-SLLLKYLTFVDEQEDDVQGTATSIKKAEKFVGTDSFALFMGDCLFVDLTNSI 119

Query: 117 SPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFY 176
              LR        +      V D   F    FD ++    + EK   P    AV G Y +
Sbjct: 120 FNDLREEFEERGVSLTITVPVKDARAFSY--FDGDY----IIEKGSDPTRKNAVPGFYIF 173

Query: 177 DSKVVEYAKQVKPSERGELEITS-INQM-----YLEAGNLTVELLGRGFAWLDTGTHDSL 230
            S V  Y  ++  SER E EI S IN M     ++ AG+           W+DTG+ D L
Sbjct: 174 KSDVFSYIDKISKSERNEYEIVSAINLMVKDKQFINAGH------KYSLVWMDTGSMDGL 227

Query: 231 IEASTFVQTVEKRQG 245
             AST +  +E   G
Sbjct: 228 KNASTLIALLENTTG 242


>UniRef50_Q9KD03 Mannose-1-phosphate guanyltransferase n=1 Tax=Bacillus halodurans
           RepID=Q9KD03_BACHD
          Length = 249

 Score = 99.8 bits (247), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 73/244 (29%), Positives = 122/244 (50%), Gaps = 16/244 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIIT---TPED 57
           MKG+ILAGG GTRL P+T  + K +LPI   P + + L+ L   GIR+I+++      + 
Sbjct: 1   MKGVILAGGRGTRLKPLTDQIPKPMLPIAGVPCLAHGLAHLAAHGIRDIVMLVHYLNHQM 60

Query: 58  KGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
           K YFQ    DGS++G+++ Y ++ +P G A +    E +L+ EP  ++ GD +       
Sbjct: 61  KAYFQ----DGSKYGMRITYVQEDAPLGTAGSLKAAERYLD-EPFVVMSGD-VLTTISIQ 114

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAV--TGLYF 175
             +     +    T+   +V + + +GVV+   N R ++  EKP + K+   +  TGLY 
Sbjct: 115 EAIVFHKRQNSLMTMLTKRVKNGQNYGVVQTGPNHRVVAFREKPTEDKTREVLVNTGLYV 174

Query: 176 YDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAST 235
            D  V+ Y  +    + G+  I      YL    L +  L  G  W D G+    ++A+ 
Sbjct: 175 MDPFVLSYIPKGSAVDLGKDVIP-----YLVDRKLDIFALEGGGYWRDIGSFHDYLQANN 229

Query: 236 FVQT 239
            V +
Sbjct: 230 DVNS 233


>UniRef50_D2RY68 Nucleotidyl transferase n=2 Tax=Halobacteriaceae RepID=D2RY68_9EURY
          Length = 248

 Score = 98.2 bits (243), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 63/210 (30%), Positives = 106/210 (50%), Gaps = 6/210 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ ++LA G GTRL P+T    K L+ + DKP+I      L+  G+ +I+++   + +  
Sbjct: 1   MQAVVLAAGKGTRLRPLTDDKPKVLVEVNDKPLIEDVFDNLLEIGVNDIVVVVGYQKEQI 60

Query: 61  FQRLLGDGSEF-GIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK 119
            +R    G E+ G+ + YA Q    GLA A +  E  ++ E   L+LGDN+F G      
Sbjct: 61  IERY---GDEYEGVPITYAHQRKQLGLAHAILQAEPHID-EDFVLMLGDNVFRGNLGDVV 116

Query: 120 LRHVAARTEGA-TVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDS 178
            R    R + A  V      +  R+GV++ ++    + + EKP  P SN  +TG Y +  
Sbjct: 117 NRQQEDRADAAFLVEEVPYEEASRYGVLDTNEYGEIVEVVEKPDDPPSNLVMTGFYTFTP 176

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAG 208
            +      V+PS+RGE E+     + +++G
Sbjct: 177 AIFHACHLVQPSDRGEYELPDAIDLLIQSG 206


>UniRef50_A6UUQ4 Glucosamine-1-phosphate N-acetyltransferase n=6 Tax=Methanococcales
           RepID=GLMU_META3
          Length = 411

 Score = 97.1 bits (240), Expect = 7e-19,   Method: Compositional matrix adjust.
 Identities = 64/238 (26%), Positives = 122/238 (51%), Gaps = 16/238 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M  +IL  G GTRL P+T  + K +LP+   P++   ++ +    +  I +I       Y
Sbjct: 1   MDAVILCAGKGTRLMPLTENIPKPMLPVGGAPILERIINKIDKL-VENIYLIVK-----Y 54

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            + ++ +  +   ++++ EQ   DG   A ++ +  ++G+   LV+  +I F       L
Sbjct: 55  EKEIIINHFKNNDKIKFIEQTDIDGTGYAVLMAKNHISGD--FLVINGDIIFDD----DL 108

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
            ++        +   +V +P  FGV+  D+    I L+EKPK PKSN    G+Y +++K+
Sbjct: 109 TNIVNDDVKNIITLNEVDNPSNFGVIVVDNQNNIIELQEKPKNPKSNLINAGIYKFENKI 168

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLT-VELLGRGFAWLDTGTHDSLIEASTFV 237
            +  + ++PSERGE+E+T   +  ++  N+  ++L G    W D G    L++A+T +
Sbjct: 169 FDILETLRPSERGEVELTDAIKELIKENNIKGIKLNGY---WNDIGKPWDLLDANTHI 223


>UniRef50_A1S0Y5 UDP-glucose pyrophosphorylase n=1 Tax=Thermofilum pendens Hrk 5
           RepID=A1S0Y5_THEPD
          Length = 296

 Score = 96.7 bits (239), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 73/270 (27%), Positives = 118/270 (43%), Gaps = 43/270 (15%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYD--------KPMIYYPLSVLMLAGIREILIIT 53
           K +I A G GTRL PIT+ + K++LP++         KP+I+     L+  G+ E+  I 
Sbjct: 4   KAVITAAGLGTRLLPITKELPKEMLPLFSVSDNAVGLKPIIHIVFESLLGVGVSEVCFIV 63

Query: 54  -----------TPEDKGYFQRLLGDGSEF-------------GIQLEYAEQPSPDGLAQA 89
                      TP D  + + L   G E                ++ +  QP P G   A
Sbjct: 64  GKSKRAIEDYFTP-DADFIEVLRAKGVENRANELMKFYSAIRNAKIFFINQPEPRGFGDA 122

Query: 90  FIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHVAARTE---GATVFGYQVMDPERFGVV 146
            +  E F+  +P  +  GD+    +G +   R V    E    AT+    V DP  +GV+
Sbjct: 123 VLRAEPFVGADPFIVHAGDDAVISEGHNHLRRLVKVFQEYDCDATLLAEDVEDPRAYGVL 182

Query: 147 ------EFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEIT-S 199
                 ++    R + + EKP++P +N A   +Y +  K+  Y + VKP   GE+++T +
Sbjct: 183 RGKVVNDYGSILRVLDIIEKPREPPTNIAAIAVYAFKPKIFSYLRNVKPDSGGEVQLTAA 242

Query: 200 INQMYLEAGNLTVELLGRGFAWLDTGTHDS 229
           I  M  +  ++    L  G   LD GT  S
Sbjct: 243 IKAMIDDGCDVCAVKLKPGERRLDVGTPQS 272


>UniRef50_UPI0001C42A13 Nucleoside-diphosphate-sugar pyrophosphorylase fused to
           phosphomannomutase n=1 Tax=Bacillus pseudofirmus OF4
           RepID=UPI0001C42A13
          Length = 808

 Score = 95.9 bits (237), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 65/194 (33%), Positives = 96/194 (49%), Gaps = 11/194 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITT---PED 57
           MKG+I+AGG GTRL P+T  + K ++P+  KP++ Y + +L   GI +I +       E 
Sbjct: 1   MKGVIMAGGKGTRLRPLTCQLPKPMVPLLQKPVMQYSIELLKQHGITDIAVTVHYLPDEI 60

Query: 58  KGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
           + YF    GDG EFG+ L Y E+  P G A +    E FL+ EP  +V GD +       
Sbjct: 61  RDYF----GDGQEFGVHLTYFEETEPLGTAGSVKQAEAFLD-EPFVVVSGDAL-TDFDLE 114

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPK--SNWAVTGLYF 175
             +    A+    ++F  QV  P  FGV+  +     I   EKP   +  S+   TG+Y 
Sbjct: 115 AGINFHKAKDALVSIFMKQVPCPLEFGVIMTNQQHEIIRFLEKPSVSEVFSDTVNTGIYV 174

Query: 176 YDSKVVEYAKQVKP 189
            D  +  Y +  KP
Sbjct: 175 MDPSIFNYIESDKP 188


>UniRef50_B8D6C9 Glucose-1-phosphate thymidylyltransferase n=1 Tax=Desulfurococcus
           kamchatkensis 1221n RepID=B8D6C9_DESK1
          Length = 427

 Score = 95.5 bits (236), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 72/249 (28%), Positives = 118/249 (47%), Gaps = 16/249 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVL-MLAGIREILIITTPEDKG 59
           MK +ILA G+G RL PIT    K L+PI  KP++ + L  L  ++ I E++I+T     G
Sbjct: 1   MKAVILAAGNGIRLKPITETRPKPLIPILCKPLLDWHLDRLAAVSFIDEVVIVT-----G 55

Query: 60  YFQRLLGD---GSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGF 116
           Y   ++           ++ + EQ  P G   A + G   +  +   L++  +IF     
Sbjct: 56  YMGDIIRAHVMSRRLPFKVRFVEQGEPRGTGDAVVKGIEGMGSDDDVLIIYSDIFTPVNI 115

Query: 117 SPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFY 176
            P++    A   G  + G +V +P  +GV+  + N+    + EKP  P S     G+Y  
Sbjct: 116 IPEI----AGESGNIIVGSEVDNPSDYGVLINEGNYFK-GVVEKPMNPPSRLVNAGIYKL 170

Query: 177 DSKVVEYAKQVKPSERGELEITSI-NQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAST 235
            ++ +     +KPS RGELE T + N M      + +  L R   W+D G    +IEA+ 
Sbjct: 171 RTRDILDNSDIKPSPRGELEFTDVLNNMSRRGVKIRIYKLPRAL-WIDIGKPWHVIEANK 229

Query: 236 FVQTVEKRQ 244
              T+ K++
Sbjct: 230 MALTMVKKE 238


>UniRef50_A7GSW4 Nucleotidyl transferase n=73 Tax=cellular organisms
           RepID=A7GSW4_BACCN
          Length = 785

 Score = 94.4 bits (233), Expect = 5e-18,   Method: Compositional matrix adjust.
 Identities = 77/246 (31%), Positives = 112/246 (45%), Gaps = 33/246 (13%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+ILAGG G RL P+T  V K +LP+ +KP++ Y + +L   GIREI  IT       
Sbjct: 3   MKGVILAGGKGRRLRPLTCNVPKPMLPLLEKPVLEYNIELLRRHGIREI-AITVQYLSNT 61

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGD---------NIF 111
            +   GDGS++G++L Y E   P G A +    E FL+ EP  ++ GD          I 
Sbjct: 62  IREYFGDGSKWGVKLHYFEDSPPLGTAGSIKQAEAFLD-EPFVVISGDALTDFPLTEGIV 120

Query: 112 FGQGFSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWA 169
           F Q           +    T+F  +V +P  FG+V  +     I   EKP   +  SN  
Sbjct: 121 FHQ----------QKKRMLTMFVKEVENPLSFGLVVMNKEQEIIRYMEKPSWNEVISNVV 170

Query: 170 VTGLYFYDSKVVEYAKQVKPSERGELEITSINQMY--LEAGNLTVELLGRGFAWLDTGTH 227
            TG+Y  D  +  Y   + P    +        ++  LE  N        G+ W+D GT 
Sbjct: 171 NTGIYIMDPSIFSY---IPPKTYADFS----RHIFPLLENTNALFGYKAEGY-WMDIGTF 222

Query: 228 DSLIEA 233
           +   +A
Sbjct: 223 EQYRQA 228


>UniRef50_A1S194 UDP-glucose pyrophosphorylase n=1 Tax=Thermofilum pendens Hrk 5
           RepID=A1S194_THEPD
          Length = 299

 Score = 93.6 bits (231), Expect = 8e-18,   Method: Compositional matrix adjust.
 Identities = 75/268 (27%), Positives = 118/268 (44%), Gaps = 36/268 (13%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPI--------YDKPMIYYPLSVLMLAGIREILIIT 53
           KG++LA G GTRL P ++ + K++LP+        Y KP+I         AGIRE   + 
Sbjct: 6   KGVLLAAGLGTRLVPYSKEMPKEMLPVFFGVNNSVYLKPVIQAVFEQFYEAGIREFCFVV 65

Query: 54  -----------TPE----------DKGYFQRLLGDGSEFGIQ--LEYAEQPSPDGLAQAF 90
                      TP+           K  +  LL D  E   +  + +  QP P G   A 
Sbjct: 66  GRGKRVIEDHFTPDWDFVEYLEKTGKNDYAELLRDFYEKVEKSYITWVNQPVPRGTGHAV 125

Query: 91  IIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQVMDPERFGVV---E 147
            + + F+  +       DN+F G+    +L     R     +   +V DP R+GVV    
Sbjct: 126 YMAKGFVGDDYFMAAATDNLFLGENIPRRLLEYFDRLRSPMLAVKRVRDPRRYGVVIGSR 185

Query: 148 FDDN-FRAISLEEKPKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLE 206
            D + +R   + EKP++P S  A T LY +  ++    +Q  PS RGELE+T   Q+ + 
Sbjct: 186 VDTSIYRVEGIVEKPREPLSYLANTSLYIFPPEIFRAIEQTTPSPRGELEVTDSIQILIR 245

Query: 207 AGNLTVELLGRGFAWLDTGTHDSLIEAS 234
           +G            W+D GT ++ + A+
Sbjct: 246 SGYQFYAYEAEA-DWIDIGTWETFLRAA 272


>UniRef50_Q2NES5 Predicted nucleoside-diphosphate-sugar pyrophosphorylase n=10
           Tax=cellular organisms RepID=Q2NES5_METST
          Length = 431

 Score = 92.8 bits (229), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 75/242 (30%), Positives = 117/242 (48%), Gaps = 15/242 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK IIL  G GTR+ P+T    K +L    KP+I Y +  L  AGI++I ++   + K  
Sbjct: 1   MKAIILTAGEGTRMRPLTTTRPKTMLITGGKPLIQYNIESLRDAGIKDITLVVGYK-KEV 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDGSE+G+ + YA Q    G A A    E ++  + S +VL  +I         L
Sbjct: 60  IEDYFGDGSEYGVNITYAVQEGQLGTAHAIGSAEEYI--DESFIVLNGDIIVSYDLIRNL 117

Query: 121 -RHVAARTEG---ATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLY 174
               A RT     + +   +V DP  +G+V   +N +   + EKP  +   SN A  G+Y
Sbjct: 118 IEKYATRTSNNVKSVLTLIEVDDPSSYGIVST-ENGKITEIIEKPSVEDAPSNLANAGIY 176

Query: 175 FYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLG--RGFAWLDTGTHDSLIE 232
            +  ++ +  ++ + S+RGE EIT    + L  G    E+LG      W+D G    L+E
Sbjct: 177 LFSPEIFDAIRKTELSKRGEYEITDSLDIELSEG---WEILGLISNEKWMDVGRPWELLE 233

Query: 233 AS 234
            +
Sbjct: 234 CN 235


>UniRef50_B3T1I2 Putative Nucleotidyl transferase n=1 Tax=uncultured marine
           microorganism HF4000_010I05 RepID=B3T1I2_9ZZZZ
          Length = 295

 Score = 92.4 bits (228), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 76/264 (28%), Positives = 124/264 (46%), Gaps = 35/264 (13%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDK--- 58
           K +I A G GTR  P+T+ V K+LLPI +KPM+ Y +     AGI++++I+ +P  +   
Sbjct: 13  KAVIPAAGLGTRFLPVTKAVPKELLPILEKPMLQYVVEEAAEAGIQQVIIVISPGKESIA 72

Query: 59  GYFQ------RLLGDGSEFGI-----------QLEYAEQPSPDGLAQAFIIGETFLNGEP 101
            YFQ      R L D    G+            + +  Q +P GL  A +     +  EP
Sbjct: 73  AYFQPQPELERYLADSEAAGLLEKVGHATSLADVSFVIQENPLGLGHAVLTAREAVANEP 132

Query: 102 SCLVLGDNIF-FGQGFSPKLRHVAARTEGATVFGYQVMDPER---FGVVEFDD------N 151
             ++L D+I     G   ++  VA R  GA V   + M  +R   +GVV+          
Sbjct: 133 FVVILPDDIIAHSPGVVSQMVAVAQR-RGAGVVAVERMPWDRVQNYGVVDASQVEERVYQ 191

Query: 152 FRAISLEEKPKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNL- 210
            R +  +  P++  SN  V G Y    ++ +  ++  P  +GE+++T    + L++  L 
Sbjct: 192 IRGMVEKPPPEEAPSNLTVVGRYILPPEIFDCLERTLPGAKGEIQLTDGLTILLDSQKLY 251

Query: 211 TVELLGRGFAWLDTGTHDSLIEAS 234
             E LGR +   D GT   L++AS
Sbjct: 252 AYEFLGRRY---DGGTPLGLLQAS 272


>UniRef50_Q0W4J0 Glucose-1-phosphate thymidylyltransferase n=2 Tax=Euryarchaeota
           RepID=Q0W4J0_UNCMA
          Length = 400

 Score = 92.4 bits (228), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 66/233 (28%), Positives = 115/233 (49%), Gaps = 26/233 (11%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++LA G G+RL P T    K ++P+ +KP++ Y ++ L  +GI +I+++      GY
Sbjct: 1   MKAVVLAAGEGSRLKPFTATRPKVMIPVGNKPILEYVINALQESGIIDIVMVV-----GY 55

Query: 61  ----FQRLLGDGSEFGIQLEYAEQPSPDGLAQAF-----IIGETFLNGEPSCLVLGDNIF 111
                    GDG ++G+ + Y EQ    G A A      +I + FL      ++ GD + 
Sbjct: 56  KREKIMDYFGDGHKWGVNITYVEQFQQLGTAHALRQASHLIKDHFL------VINGDTVI 109

Query: 112 FGQGFSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKS-NWAV 170
                   +++   +   AT+    V   + +GVVE  +N     +EEKPK  ++ N   
Sbjct: 110 DASAIKEIIKY---KVGDATMLTVSVDKAQAYGVVETQNNLVK-GIEEKPKYKEAGNIVN 165

Query: 171 TGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLD 223
            G+Y +  KV ++ + +  SERGE E+T   +  +E+ N +V  +     W+D
Sbjct: 166 AGVYCFSPKVFDFLEYMDISERGEYEVTDAIRKMIES-NYSVRAVHTSALWMD 217


>UniRef50_Q8TWY9 Nucleoside-diphosphate-sugar pyrophosphorylase involved in
           lipopolysaccharide biosynthesis; translation initiation
           factor eIF2B subunit n=1 Tax=Methanopyrus kandleri
           RepID=Q8TWY9_METKA
          Length = 425

 Score = 92.4 bits (228), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 77/287 (26%), Positives = 136/287 (47%), Gaps = 20/287 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIIT---TPED 57
           M GI+LA G GTR+ P+T+   K LLP+ D+ +I + +  +   G+  ++++      + 
Sbjct: 1   MIGIVLAAGEGTRMRPLTKTRPKVLLPVADRRLIDFSIEAMKRIGVEHLVVVVEYLAEKV 60

Query: 58  KGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
           + Y +   GD  E    LE+  Q  P G A A  +    +  + + ++   ++ F    S
Sbjct: 61  ERYVKDRWGDSFE----LEFVRQGKPLGTAHAVYVAWREIEPDETVVITNGDLVFD---S 113

Query: 118 PKLRHVAARTEG-ATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLY 174
             L       EG A++   +V DP  FGV    D +  + L EKPK  +  SN A  G+Y
Sbjct: 114 ELLERAVREHEGVASMVLVEVEDPSEFGVARLQDGY-VVELVEKPKPEEAPSNLANAGVY 172

Query: 175 FYDSKVVEYAKQVKPSERGELEIT-SINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEA 233
             + +   + ++VKPS RGE EIT ++    ++ G L +     GF W D G    L++A
Sbjct: 173 VAEPEFERFLERVKPSPRGEFEITDALLDAAIDEGVLGISY--DGF-WSDVGRPWDLLDA 229

Query: 234 STF-VQTVEKRQGFKIACLEEIAWRNG-WLDDEGVKRAASSLAKTGY 278
           + + ++    R   +    E +  R   W+ ++ + R+ + +    Y
Sbjct: 230 NAWALRNAMSRPEVEGVIEENVELRGPVWVAEDAILRSGAVVEGPAY 276


>UniRef50_C3LKU6 Nucleotidyl transferase family protein n=8 Tax=Bacillus
           RepID=C3LKU6_BACAC
          Length = 679

 Score = 91.7 bits (226), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 75/235 (31%), Positives = 110/235 (46%), Gaps = 11/235 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+ILAGG G RL P+T    K +LP+ +KP++ Y + +L   GIREI  IT       
Sbjct: 1   MKGVILAGGKGRRLRPLTCNTPKPMLPLLEKPVLEYNIELLRQHGIREI-AITVQYMSTA 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            ++  GDGS++G+ L Y E   P G A +    E FL+ E   ++ GD +   Q  S  +
Sbjct: 60  IKQYFGDGSKWGVNLYYFEDSPPLGTAGSIKQAEKFLD-ETFVVISGDALTDFQ-LSKGI 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDS 178
                +    T+F  +V +P  FG+V  +         EKP   +  SN   TG+Y  + 
Sbjct: 118 TFHEQQKRMVTMFVKEVENPLSFGLVVMNKEQEVTRYIEKPSWNEVVSNIVNTGIYIMEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEA 233
           ++  Y   + P E  +          L   N     L  G+ WLD GT D   +A
Sbjct: 178 EIFSY---IPPREFFDFSQDVFP--LLANKNALFAYLSEGY-WLDIGTFDQYRQA 226


>UniRef50_A6CNU8 Mannose-1-phosphate guanyltransferase (Pyrophosphorylase domain and
           phosphomannomutase domain) n=1 Tax=Bacillus sp. SG-1
           RepID=A6CNU8_9BACI
          Length = 345

 Score = 91.3 bits (225), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 61/176 (34%), Positives = 88/176 (50%), Gaps = 5/176 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+ILAGG GTRL P T  V K ++ I +KP++ Y +++L   GI  I+ ITT      
Sbjct: 1   MKGVILAGGKGTRLKPYTLTVPKPMVTIMNKPILEYNIALLKANGITSIM-ITTCYKADK 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                GDGSEFG+ + Y  +  P G A        +LN EP  ++ GD  F        +
Sbjct: 60  ISEYFGDGSEFGVDITYFHEDFPLGTAGGVFESSHYLN-EPFVVISGD-AFTTLSLRDAI 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAV--TGLY 174
                +    T+ G ++ DP  +GV + D   R I   EKP+  + N  +  TG+Y
Sbjct: 118 EFHQLKGSPLTIVGKEMEDPRGYGVCKTDSEGRLIEFAEKPESGEINSKLVNTGIY 173


>UniRef50_UPI0001C315BB Nucleotidyl transferase n=1 Tax=Conexibacter woesei DSM 14684
           RepID=UPI0001C315BB
          Length = 366

 Score = 90.9 bits (224), Expect = 5e-17,   Method: Compositional matrix adjust.
 Identities = 72/236 (30%), Positives = 109/236 (46%), Gaps = 12/236 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +ILAGG GTRL P+T  V K ++P+ D+P I + L  L   G+ +++I       G 
Sbjct: 1   MQALILAGGEGTRLRPLTSTVPKPVVPLVDRPFIAFMLDWLRRHGVDDVVISCGFMASG- 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            + +LGDGS FGI+L Y E+P P G   A    E  L+     LVL  ++      + +L
Sbjct: 60  VRNVLGDGSAFGIRLRYVEEPRPLGTGGAIKFAEPLLD--ERVLVLNGDVLTDIDLTAQL 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
                     T+    V DP  +G+V  D++       EKP   Q  +N    G Y  + 
Sbjct: 118 AQHERTGARVTLALIAVDDPSAYGLVRRDEDGGVREFLEKPSPDQIDTNLVNAGAYVLER 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
           +V++      P+ER       +    +  G    E  G    WLD GT +  ++AS
Sbjct: 178 EVLD----AIPTERAVSVEREVFPTLVRNGLYGYEASGY---WLDIGTPERYLQAS 226


>UniRef50_C0GGS0 Nucleotidyl transferase n=1 Tax=Dethiobacter alkaliphilus AHT 1
           RepID=C0GGS0_9FIRM
          Length = 385

 Score = 90.1 bits (222), Expect = 9e-17,   Method: Compositional matrix adjust.
 Identities = 70/231 (30%), Positives = 119/231 (51%), Gaps = 27/231 (11%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIIT--TPEDK 58
           +K +ILA G GTRL P+T  VSK ++ + ++P + + + +L   G+++I++     PE  
Sbjct: 31  IKAMILAAGLGTRLRPLTNSVSKPMVEMANRPCMEHAVRLLAKYGVKDIVVNLHYMPE-- 88

Query: 59  GYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGD---NIFFGQG 115
              Q   GDGS FG+ + Y+ +    G A  F   + F   EP+ ++ GD   ++   Q 
Sbjct: 89  -IIQEHFGDGSAFGVNITYSYEKELMGTAGGFKRVQKFFGDEPALIISGDALTDVNLEQL 147

Query: 116 FSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGL 173
           +     + A     AT+   QV DP ++GVV  + N + +  +EKPK  +  SN A TG+
Sbjct: 148 YKFHKENEAI----ATLALKQVADPTQYGVVVREGN-KIVQFQEKPKLEEAISNLANTGI 202

Query: 174 YFYDSKVV---------EYAKQVKPS--ERGELEITSINQMY-LEAGNLTV 212
           Y +D ++          ++ KQV P   E+GE     + + Y  + G+LT+
Sbjct: 203 YLFDPRIFDHIPADTFYDFGKQVFPELLEKGEKMCGYVMKEYWCDVGDLTM 253


>UniRef50_B9LMT7 Nucleotidyl transferase n=2 Tax=Halobacteriaceae RepID=B9LMT7_HALLT
          Length = 391

 Score = 90.1 bits (222), Expect = 9e-17,   Method: Compositional matrix adjust.
 Identities = 70/267 (26%), Positives = 126/267 (47%), Gaps = 24/267 (8%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +  ++LA G G RL P+T    K ++P+ ++P++ + +  +  AGI  I ++      GY
Sbjct: 6   VTAVVLAAGEGRRLEPLTNRRPKPMVPVANRPLLEHVVEAVAAAGINRIALVV-----GY 60

Query: 61  FQRLL----GDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGF 116
            Q  +    GDG ++G+ +EY EQ +  G   A +  E  ++G P  ++ GD I      
Sbjct: 61  RQERIRNHFGDGDDWGVTIEYVEQSTQLGTGHAVLQAEPVVDG-PFVVLNGDRIVDAAVV 119

Query: 117 SPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQP-KSNWAVTGLYF 175
           S ++R +A   +   +       P  +GVV  D + R   ++EKP+ P ++N    G+Y 
Sbjct: 120 S-RVRDLARDGDHPAMAVTTAERPREYGVVTLDGD-RVTGIDEKPEGPVETNRINAGVYA 177

Query: 176 YDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDT-------GTHD 228
           +   V +  ++   +  GEL IT+       AG+LT   +G    WLD        G + 
Sbjct: 178 FSPAVFDAIRETHTT--GELAITATLNELASAGDLTA--VGYDGRWLDVSNLWDLLGVNA 233

Query: 229 SLIEASTFVQTVEKRQGFKIACLEEIA 255
           +LI  S   +  +   G  +   +++A
Sbjct: 234 ALIGESEQTEPTDAAFGASVTVADDVA 260


>UniRef50_Q2FRV9 Nucleotidyl transferase n=7 Tax=cellular organisms
           RepID=Q2FRV9_METHJ
          Length = 401

 Score = 89.7 bits (221), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 64/227 (28%), Positives = 106/227 (46%), Gaps = 19/227 (8%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY--- 60
           +ILA G G R+ P+T    K +LP+  +PM+ + L+ +M AGI + + +      GY   
Sbjct: 5   VILAAGEGKRMRPLTGSRPKVMLPLAGRPMLEHLLNAVMDAGITDFIFVV-----GYGEA 59

Query: 61  -FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK 119
             +   GDG+  GI + Y  Q    G   A +     ++ +   L+ GD +         
Sbjct: 60  SVRNFFGDGTSKGISIRYVTQKRQQGTGDALMTVRPHVHSQ-FLLLNGDMVLHSDDIKAM 118

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSK 179
           L+     T    +  +    P+ +GVV  D +     LEEK   PKS+    G+Y ++  
Sbjct: 119 LK-----TPAPAMGVFTSNHPQDYGVVTMDGDI-ITGLEEKSLHPKSDLINAGMYLFEPG 172

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGT 226
           + E  + ++PS RGELE+T     Y++  N T+  +   F W D G+
Sbjct: 173 IFEELETIRPSPRGELELTDALMTYIQ--NKTLRGVRLSF-WADMGS 216


>UniRef50_Q67RD1 Glucose-1-phosphate thymidylyltransferase n=1 Tax=Symbiobacterium
           thermophilum RepID=Q67RD1_SYMTH
          Length = 364

 Score = 89.7 bits (221), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 68/225 (30%), Positives = 104/225 (46%), Gaps = 10/225 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           ++ ++L    GTRL P+T   +K  LP+  +P+  +  S L   G  EI ++  P  +  
Sbjct: 10  VRALVLCASRGTRLRPLTHTWAKASLPVAGRPIWQHIFSYLAAHGFDEIGVVVGPGQEEL 69

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            + +     +   ++    Q  P G+A A      FL  +P  L LGDN+       P L
Sbjct: 70  ARSVKRWSPQ---RVTVILQAEPAGIAHAVAAARPFLADQPFLLYLGDNLTNAD-LGPAL 125

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           R   A    A +   +V DP  FGV   D   R  ++ EKP +P S+ A+ G+YF+  +V
Sbjct: 126 RRFRAEAPSALITLQRVADPRTFGVAVLDGG-RVTAVAEKPAEPTSDLAIAGIYFFSPEV 184

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTV--ELLGRGFAWLD 223
                 + PS RGELEIT      +  G + +  EL G    W+D
Sbjct: 185 HAAIAGLTPSARGELEITDAIARLIAGGRIVLGHELSGW---WVD 226


>UniRef50_C8SCM3 Nucleotidyl transferase n=1 Tax=Ferroglobus placidus DSM 10642
           RepID=C8SCM3_FERPL
          Length = 390

 Score = 89.4 bits (220), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 73/230 (31%), Positives = 118/230 (51%), Gaps = 30/230 (13%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +ILA G G RL P T    K ++ + +KP++ Y +  L  AGIREI+++      GY
Sbjct: 1   MKAVILAAGEGQRLRPFTANKPKVMIKVGNKPILEYVVDALKEAGIREIVMVV-----GY 55

Query: 61  FQRLL----GDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVL-GDNIFFGQG 115
            +  +    G+G +FG+++EY  Q    G A A    +  + G+   LVL GDNI     
Sbjct: 56  KKERVIDYFGNGEKFGVKIEYVTQKQQLGTAHALKQAKDLVEGK--FLVLPGDNII---- 109

Query: 116 FSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYF 175
            S  L+ V +    + V+   V +P ++GV+E  +N +   + EKP++  S  A TG+Y 
Sbjct: 110 DSETLKDVLSYDTFSVVYKV-VEEPTKYGVLEV-ENGKVKRIIEKPEEEVSYLASTGIYL 167

Query: 176 YDSKVVEYAKQVKPSERGELEITSINQMYLEAGN--LTVELLGRGFAWLD 223
            D ++ E+          E ++T++  + +E+G    TVE  G    WLD
Sbjct: 168 LDDRIFEFIGD-------ERDLTNVVNVMIESGIDFFTVESKG---LWLD 207


>UniRef50_B9XHJ7 Putative glucose-1-phosphate thymidylyltransferase n=1
           Tax=bacterium Ellin514 RepID=B9XHJ7_9BACT
          Length = 100

 Score = 89.0 bits (219), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 44/88 (50%), Positives = 56/88 (63%)

Query: 195 LEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEKRQGFKIACLEEI 254
           +EIT++N  YL  G L V  L RGFAWLD GT  SL EAS +VQT+EKRQG KI C EE 
Sbjct: 1   MEITAVNVEYLNRGQLRVHRLNRGFAWLDAGTSSSLHEASAYVQTIEKRQGIKIGCPEEA 60

Query: 255 AWRNGWLDDEGVKRAASSLAKTGYGQYL 282
           A+ +G+L    ++   + + K  Y  YL
Sbjct: 61  AFHSGFLSLHELESLTAKIPKCEYRDYL 88


>UniRef50_C7P380 Nucleotidyl transferase n=20 Tax=Halobacteriaceae
           RepID=C7P380_HALMD
          Length = 253

 Score = 89.0 bits (219), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 64/220 (29%), Positives = 102/220 (46%), Gaps = 26/220 (11%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++LA G GTRL P+T    K ++ +  KP++ +    L+  G  E+L++      GY
Sbjct: 1   MKAVVLAAGEGTRLRPLTEDKPKGMVEVAGKPILTHCFEQLIELGADELLVVV-----GY 55

Query: 61  FQRLLGDG--SEF-GIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
            ++++ +    EF G+ + YA Q    GLA A +  E  ++ +   L+LGDNIF      
Sbjct: 56  KKQVIINHFEDEFEGVPITYAHQRDQKGLAHALLTVEEHIDDD-FMLMLGDNIFQANLRD 114

Query: 118 PKLRHVAARTEGATVFG---------YQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNW 168
              R    R + A +           Y V D  ++G +E         + EKP  P SN 
Sbjct: 115 VINRQREERADAAFLVEEVPWEEASRYGVCDTNKYGEIE--------EVVEKPDDPPSNL 166

Query: 169 AVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAG 208
            +TG Y +   +      V+PS R E EI+    + L +G
Sbjct: 167 VMTGFYTFTPAIFHACHLVQPSNRDEYEISDAIDLLLHSG 206


>UniRef50_A3DK29 Nucleotidyl transferase n=13 Tax=Clostridia RepID=A3DK29_CLOTH
          Length = 349

 Score = 88.6 bits (218), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 65/228 (28%), Positives = 110/228 (48%), Gaps = 10/228 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +K + LAGG GTRL PIT  + K ++PI  KP++   +  L   GI E+ +++T      
Sbjct: 3   VKALFLAGGLGTRLRPITNDLPKPMVPIMGKPLLERNIEKLKSYGIDEV-VLSTCYKPHK 61

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
             +  GDG +FG+++ Y  +  P G A A    E  L+   + LV   +I      +  +
Sbjct: 62  IDKYFGDGKKFGVKISYITEDKPLGTAGAIKNAEELLSD--TFLVFNADILSDIDIANMI 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
           R    +   AT+   +V +P  +GV+E DD+    + +EKP+  + KSN    G+Y ++ 
Sbjct: 120 RFHKEKGALATIAVTKVDNPSAYGVIEHDDDNFITAFKEKPQPHESKSNLINAGVYIFEK 179

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGT 226
           +++ +     P  R          + LE G   + +  +   WLD GT
Sbjct: 180 ELLNHI----PRGRAVSIERETYPLLLEKG-YKMAVYNKCGYWLDLGT 222


>UniRef50_Q3AQC4 Glucose-1-phosphate thymidylyltransferase n=12 Tax=Chlorobiaceae
           RepID=Q3AQC4_CHLCH
          Length = 349

 Score = 88.2 bits (217), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 76/246 (30%), Positives = 113/246 (45%), Gaps = 30/246 (12%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK II   G GTRL P T    K LL +  KP+I + +  L+ AGI E ++I      GY
Sbjct: 25  MKAIIPVAGVGTRLRPHTFSHPKVLLNVAGKPIIGHIMDKLIAAGITEAIVIV-----GY 79

Query: 61  FQRLLGDGSE------FGIQLEYAEQPSPDGLAQAFIIGETFL-NGEPSCLVLGDNIFFG 113
               LGD  E      + I+  +  Q    GL  A  + + ++   EP  ++LGD I F 
Sbjct: 80  ----LGDMIEEWLLQNYDIKFTFVTQSELLGLGHAISMCKPYIPEDEPLFIILGDTI-FD 134

Query: 114 QGFSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGL 173
               P L+        +T+   +V+DP RFGV    +N   + L EKP  P SN A+ GL
Sbjct: 135 VNLEPVLKSTC-----STIGVKEVVDPRRFGVA-VTENGAIVKLVEKPDTPVSNLAIVGL 188

Query: 174 YFYDS-----KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHD 228
           Y         K ++Y  +   + +GE ++T   Q  L+ G        +G  W D G  +
Sbjct: 189 YLLQHSAALFKSIDYLIEHNITTKGEYQLTDALQRLLDEGEKFTTFPVQG--WYDCGKPE 246

Query: 229 SLIEAS 234
           +L+  +
Sbjct: 247 TLLATN 252


>UniRef50_C7LZ98 Nucleotidyl transferase n=1 Tax=Acidimicrobium ferrooxidans DSM
           10331 RepID=C7LZ98_ACIFD
          Length = 854

 Score = 88.2 bits (217), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 64/209 (30%), Positives = 104/209 (49%), Gaps = 17/209 (8%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +I+AGG GTRL P+T    K LLP+ ++PMI   + +L+  GI +I I+T       
Sbjct: 1   MQAVIIAGGEGTRLRPLTSTTPKPLLPVANRPMIARVVDLLVANGIDDI-IVTVAYLGSA 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  LGDG+++G ++ Y ++ SP G A A       L  E + +VL  ++          
Sbjct: 60  IRTYLGDGTDWGARIRYLQEESPLGTAGAVRNARHLL--EDTFIVLSGDVVTTVDLEAAR 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYD- 177
           R    R   AT+    V DP  FGVV  +D+     L EKP   +  ++   TG+Y  + 
Sbjct: 118 RFHHERGASATMVLTTVPDPTEFGVVATEDSGAVTRLIEKPSWGEVFTDTVNTGVYILEP 177

Query: 178 --------SKVVEYAKQVKP---SERGEL 195
                   ++ V+++++V P    +RG L
Sbjct: 178 SVLDRIPANRAVDFSEEVFPQILDDRGAL 206


>UniRef50_C1SHR4 Nucleotidyltransferase n=1 Tax=Denitrovibrio acetiphilus DSM 12809
           RepID=C1SHR4_9BACT
          Length = 830

 Score = 87.4 bits (215), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 65/188 (34%), Positives = 98/188 (52%), Gaps = 11/188 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIIT--TPE-D 57
           MK +++AGG GTR+ P+T  + K ++P+ +KPM+ Y +  L  AGI EI+I+    PE  
Sbjct: 1   MKAVVMAGGFGTRIQPLTSSMPKPMIPVMNKPMMEYIIDALKEAGIVEIVILLYFKPEVI 60

Query: 58  KGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
           K YF    GDGS  GI++ Y       G A A    + +L+ E   +V GD +     F 
Sbjct: 61  KNYF----GDGSSKGIKIHYVLPDDDYGTAGAVKKAQKYLD-ERFIIVSGD-LISDFSFQ 114

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYF 175
             L     +   AT+    V DP +FGVV  D   + I   EKP   +  S+   TG+Y 
Sbjct: 115 EILGFHDVKNSKATITLTSVPDPLQFGVVITDKESKIIRFLEKPGWGEVFSDTINTGIYV 174

Query: 176 YDSKVVEY 183
           ++ +++EY
Sbjct: 175 FEPEILEY 182


>UniRef50_D2EEQ5 Nucleotidyl transferase n=1 Tax=Candidatus Parvarchaeum acidiphilum
           ARMAN-4 RepID=D2EEQ5_9EURY
          Length = 274

 Score = 87.0 bits (214), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 71/267 (26%), Positives = 132/267 (49%), Gaps = 30/267 (11%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K +I A G G+R++P+TR   K++LPI DKP+I++ +  ++ AGI +IL+I     +   
Sbjct: 6   KAVIPAAGLGSRMYPLTRAQPKEMLPILDKPVIHHVVDEILSAGIDQILVIVGKGKESII 65

Query: 62  QRLLGDGSEFGIQLE---------YAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFF 112
                D +E  ++           +  Q    GLA A    + F+N EP  ++ GD I+ 
Sbjct: 66  NYF--DYNELDLKFNSMPDFPEIFFVRQREQKGLADAVKYAKKFVNDEPFMVLAGDTIYG 123

Query: 113 G---QGFSPKLRHVAARTEGATVFGYQVMDPER---FGVVEFDDNFRAISL----EEKPK 162
               +  + ++  V  R + +TV G + +  E+   +G+V  D+  + + L     EKP+
Sbjct: 124 SNKEKTIAQQIIDVFNR-KSSTVIGLEKVPIEKVKHYGIVNGDEIEKGLHLIKNMVEKPE 182

Query: 163 --QPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEIT-SINQMYLEAGNLTVELLGRGF 219
             +  SN A+T  Y     +  +  ++KP +  E ++T ++N M  E     +E+ G+ +
Sbjct: 183 ISEAPSNLAITAAYALQPDIFAFIDKIKPGKNNEYQLTDALNLMCKEQDVFGIEIDGKRY 242

Query: 220 AWLDTGTHDSLIEASTFVQTVEKRQGF 246
              D G+ +  +E  TF++   K + F
Sbjct: 243 ---DIGSKEFWVE--TFIEFARKDERF 264


>UniRef50_B7GHA3 Nucleoside-diphosphate-sugar pyrophosphorylase fused to
           phosphomannomutase n=1 Tax=Anoxybacillus flavithermus
           WK1 RepID=B7GHA3_ANOFW
          Length = 815

 Score = 87.0 bits (214), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 58/194 (29%), Positives = 95/194 (48%), Gaps = 11/194 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIIT---TPED 57
           +K +I+AGG GTRL P+T  V K ++PI +KP++ Y +  L   GI +I +     + E 
Sbjct: 23  VKAVIMAGGRGTRLRPLTCHVPKPIVPIMNKPVMAYSIEWLKHHGITDIAVTVQYLSDEI 82

Query: 58  KGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
             YF    GDG  FG++L Y E+ +P G A +    ++FL+   + +V+  +I       
Sbjct: 83  IEYF----GDGRRFGVRLHYFEETTPLGTAGSVKHAQSFLDD--TFVVISADILTTMHLQ 136

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYF 175
             +    ++    TV  +    P  +G +  D N + I   EKPK  +  S+   TG+Y 
Sbjct: 137 QAIHFHFSKQALVTVLMHHEATPLSYGGIVTDRNGKVIHFVEKPKWNEVCSDLVNTGIYI 196

Query: 176 YDSKVVEYAKQVKP 189
            D  +  Y  +  P
Sbjct: 197 CDPAIFNYMPEHPP 210


>UniRef50_D1JGY1 Putative bifunctional protein glmU n=1 Tax=uncultured archaeon
           RepID=D1JGY1_9ARCH
          Length = 415

 Score = 86.7 bits (213), Expect = 8e-16,   Method: Compositional matrix adjust.
 Identities = 71/238 (29%), Positives = 109/238 (45%), Gaps = 11/238 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +ILA G G R+ P+T    K +LPI  KP+I + L  +   GI + + +    D+  
Sbjct: 15  MKALILAAGEGKRMRPLTYERPKVMLPIAGKPIIEHLLEEVKEVGIDDFIFVVGYHDE-T 73

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVL-GDNIFFGQGFSPK 119
            +   G+G  + I LEY  Q +  G A A    E  +  E   L+L GD I   +     
Sbjct: 74  IRDYFGNGERWDINLEYVTQKTQLGTADALRKAEELV--ENQFLMLNGDTIVSAKDIKKV 131

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSK 179
           + +      G      +V +PE +GVVE +   R   + EK + P SN    G+Y  D  
Sbjct: 132 INNGVNMVLGVI----EVENPEDYGVVETEGE-RITEIHEKMRVPISNLVNAGVYALDKS 186

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
           +     +   S+RGE E+T   Q+ +E+G     L  +   WLD      L+ A+ F+
Sbjct: 187 IFGVLSKTDKSKRGEFELTDSLQLLIESGEAI--LWEKIEHWLDLSYPWDLLTANEFL 242


>UniRef50_Q01PZ9 UDP-glucose pyrophosphorylase n=1 Tax=Candidatus Solibacter
           usitatus Ellin6076 RepID=Q01PZ9_SOLUE
          Length = 308

 Score = 86.7 bits (213), Expect = 9e-16,   Method: Compositional matrix adjust.
 Identities = 68/238 (28%), Positives = 105/238 (44%), Gaps = 32/238 (13%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIIT--------- 53
            ++   G GTRL P T+   K++LP+  KP++ Y +  L+  GI +IL +T         
Sbjct: 15  AVVPVAGLGTRLLPATKSQPKEMLPVARKPIVQYVVEELVSNGIEQILFVTGRSKASIEN 74

Query: 54  -TPEDKGYFQRLLGDG-----SEFGI-----QLEYAEQPSPDGLAQAFIIGETFLNGEPS 102
               D   FQ L         SE  +     +  Y  Q    GL  A +  E F   EP 
Sbjct: 75  HFDHDPELFQALTQANKQDLLSELDVVALKAKFFYTRQRMQRGLGDAIMCAENFAGEEPF 134

Query: 103 CLVLGDNIFFGQGFS---PKLRHVAARTEGATVFGYQVMDPE---RFGVVE----FDDNF 152
            + LGD+I      S    ++  V      + V   + +  E    +G+V+     DD F
Sbjct: 135 LVALGDSILGLNAVSKAVARMADVFDSKRASCVIAVEEVPAEETRHYGIVQPEAGADDVF 194

Query: 153 RAISLEEK--PKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAG 208
           R ++L EK  PK   SN A+ G Y +   + +  ++VKP +RGE+++T   Q   E G
Sbjct: 195 RVVNLVEKPAPKDAPSNLAIAGRYIFSPVLFDMIRRVKPDKRGEIQLTDAIQFMCEEG 252


>UniRef50_C9RWA3 Nucleotidyl transferase n=7 Tax=Geobacillus RepID=C9RWA3_GEOSY
          Length = 347

 Score = 86.7 bits (213), Expect = 9e-16,   Method: Compositional matrix adjust.
 Identities = 69/228 (30%), Positives = 106/228 (46%), Gaps = 10/228 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++LAGG GTRL P+T  + K + PI ++P + + +  L   G+ E  +I        
Sbjct: 1   MKALLLAGGLGTRLRPLTENIPKPMAPIANRPWLEHLIVHLRDQGVNE-FVIAAHHCSEV 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +R   DG  + +++ YA +P P G A A    E +L  +   LV   +I       P L
Sbjct: 60  IRRYFEDGKRWNVKITYALEPFPLGTAGAIKNAERWL--KERFLVFNADIVHLPQLIPLL 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPK--SNWAVTGLYFYDS 178
                    AT+   +V DP  +GVVE DD  + +   EKP++ +  SN    G+Y ++ 
Sbjct: 118 DFHRQHGGLATIVLTEVDDPSSYGVVEQDDRGQILRFVEKPRREEAPSNRINAGMYIFEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGT 226
            V+ Y     P+ER E+ I       L   N+ V  +     W D GT
Sbjct: 178 DVMRYI----PAER-EVSIERETFPLLIEKNVGVYGIVSNGYWRDMGT 220


>UniRef50_A0Q1V6 Mannose-1-phosphate guanyltransferase (Pyrophosphorylase domain and
           phosphomannomutase domain) n=4 Tax=Firmicutes
           RepID=A0Q1V6_CLONN
          Length = 817

 Score = 85.9 bits (211), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 57/188 (30%), Positives = 94/188 (50%), Gaps = 11/188 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILII---TTPED 57
           MK +I+AGG G RL P+T  + K ++PI +KP I Y + +L  +GI++I I       E 
Sbjct: 1   MKAVIMAGGLGNRLRPLTCNIPKPMMPIVNKPAIQYIIELLKNSGIKDIAITLQYLADEI 60

Query: 58  KGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
             YFQ    DGS FG+ ++Y  +  P G   +    E FL  + + +V+  +        
Sbjct: 61  MSYFQ----DGSRFGVNIKYFIEDMPLGTGGSVKNAEEFL--DDTFIVISGDALINLDLR 114

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYF 175
             +++  ++    T+   +V  P  +GVV  D+  R I   EKP   +  S+   TG+Y 
Sbjct: 115 KVVKYHKSKNAQVTIVTKKVNTPLEYGVVITDNEGRIIKFLEKPGWSEVFSDKVNTGVYV 174

Query: 176 YDSKVVEY 183
            +  V++Y
Sbjct: 175 LEPDVLKY 182


>UniRef50_A8SKG5 Putative uncharacterized protein n=1 Tax=Parvimonas micra ATCC
           33270 RepID=A8SKG5_9FIRM
          Length = 294

 Score = 85.5 bits (210), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 77/271 (28%), Positives = 129/271 (47%), Gaps = 40/271 (14%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPE----D 57
           K +I   G  TR+ P T+GV K +LPI+DKP + Y +  ++ AGI E+++I   +    D
Sbjct: 5   KVVIPTAGLATRMFPATKGVPKAMLPIFDKPTLQYVIEEVVEAGIDEVILIVNEDYFTID 64

Query: 58  KGYFQ----RLLGDGSEFGIQLEYAE-----------QPSPDGLAQAFIIGETFLNGEPS 102
           K +      R+    +     +E  E           Q    GL  A +  +  +NGE  
Sbjct: 65  KHFNSEIDLRVKNSNNVLKKDIETLEKILKCKISFIIQKEQKGLGHAILCAKEAVNGEDF 124

Query: 103 CLVLGDNIFFGQGFS--PKLRHVAARTEGATVFGYQVMDPER---FGVV---EFDDN-FR 153
           C+VLGD I   +  S   +L  +  R  G TV G +++  E+   +G++   E + N F 
Sbjct: 125 CVVLGDVIIDCKDSSCTKELVDIYNRY-GKTVVGVEIVPDEKRHNYGILEGKEIEKNIFD 183

Query: 154 AISLEEKPK--QPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEIT-SINQMYLEAGNL 210
           +  L EKP   +  SN A+ G Y   +++ E  +  K  + GE++ T S+N++ L+    
Sbjct: 184 STRLIEKPNIDETNSNLAMVGRYIVKNEIFEILENQKAGKNGEIQFTDSLNELTLKG--- 240

Query: 211 TVELLGRGFAWLDTGTHDSLIEASTFVQTVE 241
             +LLG  F   D  T+D   +    + ++E
Sbjct: 241 --DLLGYKF---DGKTYDVGNKLGVLIASIE 266


>UniRef50_D2LMS4 Nucleotidyl transferase n=3 Tax=Aciduliprofundum boonei T469
           RepID=D2LMS4_9EURY
          Length = 400

 Score = 85.5 bits (210), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 71/236 (30%), Positives = 116/236 (49%), Gaps = 18/236 (7%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+  ILA G GTR+ P+T    K L+P+ +KP+I + L  L+ AGI +I I+   E +  
Sbjct: 1   MRAFILAAGEGTRMWPLTDTRPKPLIPLANKPIIEHILDALVEAGIEKISILIGYEGRQI 60

Query: 61  FQRLLGDGSEF-GIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK 119
            +R    G  + G +++Y  Q    G   A +    + N E   ++ GD  F     S  
Sbjct: 61  AERY---GYSYKGAKIDYVYQNERRGTGDAVLYASKY-NDEKFLILNGDLYFEKSAISDI 116

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVT-GLYFYDS 178
           L H  A      V G    + E +G++  D+N   I    + K P S+  V  G+Y +  
Sbjct: 117 LGHDNA------VLGVYKDNAESYGLLIGDENLEEI----REKVPSSSGLVNAGVYVFHR 166

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
           ++ EY K+V+ S RGE+E T    M+++  +  V+++     WLD G    L++A+
Sbjct: 167 EIFEYIKRVELSPRGEIEFTDAINMFVKEHD--VKIVKYNGLWLDIGYPWHLLDAT 220


>UniRef50_Q9I291 UTP--glucose-1-phosphate uridylyltransferase n=168 Tax=cellular
           organisms RepID=GALU_PSEAE
          Length = 279

 Score = 85.5 bits (210), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 72/273 (26%), Positives = 120/273 (43%), Gaps = 45/273 (16%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K +  A G GTR  P T+ + K++LP+ +KP+I Y +   + AG+ EI I+T     G  
Sbjct: 4   KCLFPAAGYGTRFLPATKAMPKEMLPVVNKPLIQYAVEEALEAGLSEIGIVT-----GRG 58

Query: 62  QRLLGDGSEFGIQLE-------------------------YAEQPSPDGLAQAFIIGETF 96
           +R L D  +   +LE                         Y  Q    GL  A + G   
Sbjct: 59  KRSLEDHFDISYELEHQIRNTDKEKYLVGIRRLIDECTFAYTRQVEMKGLGHAILTGRPL 118

Query: 97  LNGEPSCLVLGDNIFFGQGFSPKLRHVAARTEG--ATVFGYQVMDPE---RFGVVE---- 147
           +  EP  +VL D++         L+ +         ++   Q + PE   ++GV+     
Sbjct: 119 IGDEPFAVVLADDLCLNLEGDSVLKQMVKLYNQFRCSIVAIQEVPPEETNKYGVIAGEMI 178

Query: 148 FDDNFRAISLEEKPK--QPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEIT-SINQMY 204
            DD FR  ++ EKPK  +  SN A+ G Y     + +  +Q +P + GE++IT ++ +  
Sbjct: 179 RDDIFRVNTMVEKPKPEEAPSNLAIIGRYILTPDIFDLIEQTEPGKGGEIQITDALMKQA 238

Query: 205 LEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
            +   L  +  G+ F   D G+ +  IEA+ F 
Sbjct: 239 QDGCVLAYKFKGKRF---DCGSAEGYIEATNFC 268


>UniRef50_Q6MGZ2 UTP-glucose-1-phosphate uridylyltransferase n=1 Tax=Bdellovibrio
           bacteriovorus RepID=Q6MGZ2_BDEBA
          Length = 294

 Score = 85.1 bits (209), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 68/231 (29%), Positives = 109/231 (47%), Gaps = 36/231 (15%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIIT-----TPE 56
           K II A G GTR  P T+ V K++L I D P+I Y +   + AGI +I++I        E
Sbjct: 6   KAIIPAAGLGTRFLPATKTVPKEMLTIVDAPIILYVVEEAVKAGIEDIILIAGRGKHAIE 65

Query: 57  DKGYF-------QRLLGDGSEFGIQ----------LEYAEQPSPDGLAQAFIIGETFLNG 99
           D  +F        +L  DG E  ++          +    Q    GL  A + G   +  
Sbjct: 66  D--FFDTSYELEDKLAKDGKEKLLERVTRIRDSANIISIRQKQAMGLGHAVLCGLPIVGK 123

Query: 100 EPSCLVLGDNIFFGQGFSPKLRH--VAARTEGAT----VFGYQVMDPERFGVVEFDDN-- 151
           EP  ++LGD I  G    P +    V++  E  T    V   +  D  ++G+ E ++   
Sbjct: 124 EPFAVLLGDEITMGFHGEPNVTSQLVSSFEETGTSTISVMKVEDKDVSKYGIAEIEEKST 183

Query: 152 --FRAISLEEKPKQPKSN--WAVTGLYFYDSKVVEYAKQVKPSERGELEIT 198
             F+  SL EKPK  ++N  WA+ G Y +D+ +++  +  KP+  GE+++T
Sbjct: 184 GFFKVTSLVEKPKASETNSRWALPGRYVFDNAIMDILQNAKPTLNGEIQLT 234


>UniRef50_Q3Z925 Glucose-1-phosphate thymidylyltransferase n=5 Tax=Dehalococcoides
           RepID=Q3Z925_DEHE1
          Length = 393

 Score = 85.1 bits (209), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 69/224 (30%), Positives = 103/224 (45%), Gaps = 18/224 (8%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           + +ILA G G RL P T   SK +L I  KP++ Y +  L   GIR+I+++   + +  F
Sbjct: 3   QAVILAAGEGQRLRPFTSSKSKVMLSIAGKPLLEYVIESLARNGIRDIILVVGYKRERIF 62

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL- 120
               GDG   G+++ Y  QP+  G A A       + G+   LVL  +    Q  SP   
Sbjct: 63  D-YFGDGGHLGVEITYVSQPNQLGTAHALKQTRDKIRGD--FLVLNGD----QLISPATI 115

Query: 121 -RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSK 179
              V    +   V      DP R+GVV      R  S+EEKP   KSN   TG+Y + ++
Sbjct: 116 GDFVKEPPQAVMVKAINGEDPRRYGVVS-SSGRRLTSIEEKPSIAKSNLINTGIYSFSTR 174

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLD 223
           V +Y  +        L+I  + Q  ++ G L + +      WLD
Sbjct: 175 VFDYIAE-------HLDIPMVLQSMIKDG-LDIRVAESRGVWLD 210


>UniRef50_P47691 UTP--glucose-1-phosphate uridylyltransferase n=2 Tax=Mycoplasma
           RepID=GALU_MYCGE
          Length = 292

 Score = 85.1 bits (209), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 69/275 (25%), Positives = 119/275 (43%), Gaps = 51/275 (18%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K +I A G G RL P T+ + K++LP+ +KP I Y +   + +GI +IL+I + +     
Sbjct: 7   KAVIPAAGLGVRLLPATKAIPKEMLPLVNKPTIQYIVEEAVKSGIEQILVIVSSKKTAIL 66

Query: 62  QRLLGDGSEFGIQLE-------------------------YAEQPSPDGLAQAFIIGETF 96
                D  ++ + LE                         +  Q + DGL  A +  E+F
Sbjct: 67  -----DHFDYDLILENALIQKNKLQEHKEIEDIANLAHIFFVRQKNQDGLGDAILFAESF 121

Query: 97  LNGEPSCLVLGDNIFFGQGFSPKLRHV--AARTEGATVFGYQVMDP---ERFGVVEFDDN 151
           +  E   ++LGD++ F +   P L+    A         G Q +DP   +++G++  + +
Sbjct: 122 VGNEDFAVLLGDDVVFSK--EPALKQCLEAYYETNCQTIGVQEVDPCHVDKYGIITPEGD 179

Query: 152 FR--------AISLEEKPKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQM 203
           ++        A++ + KPK  KSN A+ G Y     + +  + V     GEL++T     
Sbjct: 180 YKNKDLIKVLAMTEKPKPKDAKSNLAILGRYVLKPSIFKALRSVPYGVGGELQLTDGLNF 239

Query: 204 YLEAGNLTVELLGRGF--AWLDTGTHDSLIEASTF 236
            L+  N       R F     D GT    I+A+ F
Sbjct: 240 CLKNEN----FYARKFTGTRFDVGTKSGFIKANLF 270


>UniRef50_Q46AY5 Glucose-1-phosphate thymidylyltransferase n=4
           Tax=Methanosarcinaceae RepID=Q46AY5_METBF
          Length = 405

 Score = 84.7 bits (208), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 70/242 (28%), Positives = 118/242 (48%), Gaps = 14/242 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDK-- 58
           MK IILA G G R  P+T   SK +LPI ++P++ + +  L   GI +I++I   + +  
Sbjct: 1   MKAIILAAGEGLRCRPLTLTRSKVMLPIANRPILEHVIGSLEKNGITDIILIVGYKKERI 60

Query: 59  -GYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPS-CLVL-GDNIFFGQG 115
             YF+    DG  FG++++Y EQ +  G A A    + ++  E S  LVL GDN+   + 
Sbjct: 61  MDYFE----DGLNFGVKIKYVEQKAQLGTAHAIEQAKKWIEPEDSEFLVLNGDNLVEPKT 116

Query: 116 FSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYF 175
            +  L +       A++   Q+ +   +GVV   +  R   + EK     S    TG+Y 
Sbjct: 117 IADLLNNYEG---DASLLTVQMEETAGYGVV-LKEKKRVTRILEKRPGDLSRIVNTGIYI 172

Query: 176 YDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAST 235
           +  +V E  ++   SE GE  IT   Q+ ++ G +   +  +   W+D      L++A+ 
Sbjct: 173 FTPQVFETIEKTPISENGEYAITDTLQLMIDEGKIVTSVSTKS-KWIDAVHSWDLLKANA 231

Query: 236 FV 237
            V
Sbjct: 232 IV 233


>UniRef50_Q8SQX7 MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE n=3 Tax=Microsporidia
           RepID=Q8SQX7_ENCCU
          Length = 345

 Score = 84.0 bits (206), Expect = 6e-15,   Method: Compositional matrix adjust.
 Identities = 60/226 (26%), Positives = 108/226 (47%), Gaps = 9/226 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +K +IL GG GTRL P+T  V K L+P  +KP++ + +  L+  GI+EI++      +  
Sbjct: 8   VKAVILVGGYGTRLRPLTYTVPKPLVPFANKPILRHQIEALVKVGIKEIILALNYYSEFI 67

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            + +    +E GI + Y+++  P G A    + + +L G  +  VL  +I      +  L
Sbjct: 68  IREVRDYSNELGISIVYSKEQEPLGTAGPLALAKKYLEGH-TFFVLNSDITCRFPLAEML 126

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAI-SLEEKPKQPKSNWAVTGLYFYDSK 179
               +     T+    V DP R+G++  +++   + S  EKPK   SN    G+Y  +  
Sbjct: 127 SFHYSHGREGTILSTNVDDPSRYGIIITEESTSLVRSFLEKPKDAVSNRVNAGIYILNPS 186

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTG 225
           V++  +  + S   E+      +  L+  +L      +GF W+D G
Sbjct: 187 VLDRIELRECSIEREIFPRMAEEHQLQVFDL------KGF-WMDIG 225


>UniRef50_A7NP37 Nucleotidyl transferase n=5 Tax=Chloroflexaceae RepID=A7NP37_ROSCS
          Length = 370

 Score = 84.0 bits (206), Expect = 7e-15,   Method: Compositional matrix adjust.
 Identities = 65/198 (32%), Positives = 92/198 (46%), Gaps = 9/198 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIRE-ILIITTPEDKG 59
           MK +IL GG GTRL P+T    K ++P+ ++P I + L  L   GI E IL +    D+ 
Sbjct: 1   MKAVILVGGLGTRLRPLTCNTPKPMIPLVNQPFIVHVLENLRNQGIDEVILCVQYLADR- 59

Query: 60  YFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK 119
            F+  LGDGS  G+++   E+P P G A A    E  L+G  S  V   ++         
Sbjct: 60  -FREALGDGSVLGLKIHVIEEPEPLGTAGAVKNVEHMLDG--STFVFNGDVLTDLDLRAM 116

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYD 177
           L     R    T+    V DP  +G+VE D+        EKP+  +  SN    G Y  +
Sbjct: 117 LAFHRERGSKLTIALTPVEDPTAYGLVEMDETGHIRRFMEKPRVDEITSNLINAGTYIIE 176

Query: 178 SKVVEYA--KQVKPSERG 193
            ++  Y   KQ    ERG
Sbjct: 177 PELFRYVPPKQHYMFERG 194


>UniRef50_B8CYH8 Phosphoglucomutase n=1 Tax=Halothermothrix orenii H 168
           RepID=B8CYH8_HALOH
          Length = 820

 Score = 82.8 bits (203), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 58/185 (31%), Positives = 97/185 (52%), Gaps = 7/185 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+I+AGG G+RL P+T  + K ++P+ + P++ Y +++L   GI++I  +TT      
Sbjct: 1   MKGVIMAGGQGSRLRPLTCNLPKPMVPVMNYPVMEYIITLLKNYGIKDIA-VTTYYLPNK 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIF-FGQGFSPK 119
            +   GDGS++G+ L Y  +  P G A +      FL+ EP  ++ GD I  F  G +  
Sbjct: 60  IESYFGDGSKWGVNLHYFVEKEPLGTAGSVANARDFLD-EPFMVISGDAITDFDLGEAIS 118

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYD 177
                 +   AT+   +V  P  +GVV  D+  R +   EKP   Q  S+   TG+Y  +
Sbjct: 119 FHQ--EKGASATIVLARVKTPLDYGVVITDERGRIVRFLEKPNWGQVFSDTVNTGIYVLE 176

Query: 178 SKVVE 182
            ++ +
Sbjct: 177 PEIFD 181


>UniRef50_C9XS92 Utp--glucose-1-phosphate uridylyltransferase (General stress
           protein 33) n=335 Tax=cellular organisms
           RepID=C9XS92_CLODC
          Length = 321

 Score = 82.8 bits (203), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 67/229 (29%), Positives = 105/229 (45%), Gaps = 33/229 (14%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKG-- 59
           K +I A G GTR  P T+   K++LPI DKP + Y +   + +GI EILIIT    K   
Sbjct: 7   KAVIPAAGLGTRFLPATKAQPKEMLPIVDKPTLQYIIEEAVASGIEEILIITGRNKKSIE 66

Query: 60  -YFQR---LLGDGSEFG--------------IQLEYAEQPSPDGLAQAFIIGETFLNGEP 101
            +F +   L  D  + G              I + Y  Q  P GL  A      F+  EP
Sbjct: 67  DHFDKSVELELDLEKKGKKELLEVVQNISNMINIHYIRQKEPKGLGDAIYCARHFIGDEP 126

Query: 102 SCLVLGDNIFFGQGFSPKLRHVAARTEG--ATVFGYQVM---DPERFGVVEFDD----NF 152
             ++LGD+I       P L+ +    E    T+ G Q +   D  ++G++E  +     +
Sbjct: 127 FAVMLGDDIV--DNDVPCLKQLTDAYEEYRTTILGVQKVNQEDTNKYGIIEAKNIEGRVY 184

Query: 153 RAISLEEKPKQPK--SNWAVTGLYFYDSKVVEYAKQVKPSERGELEITS 199
           +   + EKP+  K  SN A+ G Y    ++ +  K + P + GE+++T 
Sbjct: 185 KVKDMVEKPESGKAPSNIAILGRYIITPEIFDILKDLPPGKGGEVQLTD 233


>UniRef50_A6TK87 UTP-glucose-1-phosphate uridylyltransferase n=5 Tax=Bacteria
           RepID=A6TK87_ALKMQ
          Length = 307

 Score = 82.8 bits (203), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 64/230 (27%), Positives = 106/230 (46%), Gaps = 35/230 (15%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K +I A G GTR  P T+ + K++LPI DKP + Y +   + +GI EILIIT   +K   
Sbjct: 5   KAVIPAAGLGTRFLPATKALPKEMLPIVDKPTLQYIIEEAVDSGIEEILIITG-RNKSSI 63

Query: 62  QRLLGDGSEFGIQLE---------------------YAEQPSPDGLAQAFIIGETFLNGE 100
           +       E  ++LE                     Y  Q  P GL  A    ++F+  E
Sbjct: 64  ENHFDKSIELELELEKKGKDELLKQVRAISDMVNIHYIRQKEPKGLGHAIHCAKSFIGNE 123

Query: 101 PSCLVLGDNIFFGQGFSPKLRHVAARTE--GATVFGYQVMDPE---RFGVVE----FDDN 151
           P  ++LGD+I   +   P L  +    +    T+ G Q +  E   ++G+V+        
Sbjct: 124 PFAVMLGDDIV--ENDKPCLEQMMEMYDEYKTTILGVQEVPKESVNKYGIVDGMHIEGGI 181

Query: 152 FRAISLEEK--PKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITS 199
           ++   L EK  P++  SN A+ G Y  + ++ +  +  KP + GE+++T 
Sbjct: 182 YKVKDLVEKPSPQEAPSNIAILGRYIINPEIFDILENTKPGKGGEIQLTD 231


>UniRef50_C4I7X9 UTP-glucose-1-phosphate uridylyltransferase n=43 Tax=Bacteria
           RepID=C4I7X9_BURPS
          Length = 332

 Score = 82.8 bits (203), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 63/241 (26%), Positives = 106/241 (43%), Gaps = 44/241 (18%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K +    G GTR  P T+   K++LP+ DKP+I Y +   + AGI E++ +T     G  
Sbjct: 43  KAVFPVAGLGTRFLPATKASPKEMLPVVDKPLIQYAVEEAINAGITEMIFVT-----GRS 97

Query: 62  QRLLGDGSEFGIQLE--------------------------YAEQPSPDGLAQAFIIGET 95
           +R + D  +   ++E                          Y  QP+  GL  A +  E 
Sbjct: 98  KRAIEDHFDKSFEIESELEARGKEKLLELVRGIKPSHVDCFYVRQPAALGLGHAVLCAEK 157

Query: 96  FLNGEPSCLVLGDNIFFGQGFSPKLRHVAA--RTEGATVFGYQVM---DPERFGVVE--- 147
            ++GEP  ++L D++  G    P L+ +        ++V G + +   D   +G+VE   
Sbjct: 158 LVHGEPFAVILADDLLHGD--QPVLKQLVDVFNHYHSSVIGVETIEREDSRSYGIVEGRE 215

Query: 148 -FDDNFRAISLEEK--PKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMY 204
             +D  +   + EK  P+   SN  V G Y     + E+ +++KP   GEL++T   Q  
Sbjct: 216 WEEDIIKLSGIIEKPAPEHAPSNLGVVGRYVLMPSIFEHLRKIKPGAGGELQLTDAVQSL 275

Query: 205 L 205
           L
Sbjct: 276 L 276


>UniRef50_C6A1S5 NDP-sugar synthase n=9 Tax=Thermococcaceae RepID=C6A1S5_THESM
          Length = 413

 Score = 82.4 bits (202), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 70/271 (25%), Positives = 118/271 (43%), Gaps = 40/271 (14%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +ILAGG GTRL P++    K ++P+  +P + Y L  L      + +I++    +G 
Sbjct: 1   MKAVILAGGFGTRLRPLSSTRPKPMIPVLGRPNLQYILENLQKISEIDEVILSVHYMRGE 60

Query: 61  FQRLLGDG-SEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK 119
            +  + D  S++   + +   P P     A    E  ++ E   LV+  ++F    F   
Sbjct: 61  IREFIEDKMSDYPKDIRFINDPMPLETGGALKNVEDVVSDE--FLVIYGDVFTNFNFEEL 118

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSK 179
           ++   A     TV   +V DPE++GVV  D+  + +  EEKP +PKSN    G+Y  + +
Sbjct: 119 IKAHKANDALITVALTKVYDPEKYGVVVTDEEGKIVDFEEKPLRPKSNLIDAGIYMVNKE 178

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFA----------WLDTGTHDS 229
           ++              EI    ++Y E   L  + + +G A          W+D GT + 
Sbjct: 179 ILN-------------EIPKGKEIYFEREVLP-KFVAQGLAHGYMMPRNNYWVDLGTPED 224

Query: 230 LIEASTFVQTVEKRQGFKIACLEEIAWRNGW 260
              A   +             L+EIA  NG+
Sbjct: 225 FFYAHQLI-------------LDEIAKNNGY 242


>UniRef50_UPI000038E164 mannose-1-phosphate guanyltransferase n=1 Tax=Ferroplasma
           acidarmanus fer1 RepID=UPI000038E164
          Length = 367

 Score = 81.6 bits (200), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 75/279 (26%), Positives = 135/279 (48%), Gaps = 32/279 (11%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +K +++AGG GTRL PIT  + K ++PI  KP + Y L     AGI++++I T     GY
Sbjct: 10  IKAVVMAGGKGTRLRPITYSIPKPVVPIAGKPCMLYLLDSYYNAGIKDVIITT-----GY 64

Query: 61  -FQRLLG---DGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGD-NIFFGQG 115
            F  L+    +       + ++ +  P G A +  +   F++     L++G  +I     
Sbjct: 65  KFSSLITSIIENRHNDQAILFSVEKEPAGTAGSVKMVSNFID---DTLIVGSGDILSDFN 121

Query: 116 FSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGL 173
            S  +          T+   +V DP +FG+VE ++N R +   EKP   Q  S+ A TG+
Sbjct: 122 ISDIINFHKKNKAMVTIVLTEVEDPRQFGIVEMENN-RIVRFLEKPDRDQTFSHIASTGI 180

Query: 174 YFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVEL---LGRGFAWLDTGTHDSL 230
           Y  + ++++Y   + P +  +        ++ E     +++   +G+G  WLDTG  + L
Sbjct: 181 YVIEPEILDYITTM-PYDFAK-------DLFPELMKRNIDIYGYMGKG-VWLDTGRPNDL 231

Query: 231 IEASTFVQTVEKRQGFKIACLEEIAWRNGWLDDEGVKRA 269
           I A+   Q + ++ G K + ++ I  +N  LD  G+   
Sbjct: 232 ITAN---QIMVEKYG-KPSNVDFIKGKNIILDMAGIHNT 266


>UniRef50_P42407 Putative UTP--glucose-1-phosphate uridylyltransferase n=10
           Tax=Bacillus RepID=YTDA_BACSU
          Length = 272

 Score = 81.6 bits (200), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 67/241 (27%), Positives = 113/241 (46%), Gaps = 27/241 (11%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDK--- 58
           K II AGG GTR  P+T+ + K++ P+  KP+I+Y +  L  +GI +IL++ +       
Sbjct: 4   KAIIPAGGFGTRNLPVTKVIPKEMFPVGSKPVIHYLVEELKESGIEDILMVVSSHKNLIV 63

Query: 59  GYFQ---------------RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSC 103
            YF                 LL +     I++ Y  QP   GL  A   G+ F  GEP  
Sbjct: 64  DYFDSSLALEAFLASKNKLHLLREHPIPDIRIHYVRQPYAKGLGDAISFGKQFAGGEPFA 123

Query: 104 LVLGDNIFFGQGFSPKLRHVAARTE-GATVFGY---QVMDPERFGVVEFDDN----FRAI 155
           +VL D++ F        + + A T+  ++V G    +  D   +GV++ +      +R  
Sbjct: 124 VVLPDDLIFSANQPALGQLIEAYTKYQSSVIGLKETKTEDLHHYGVIKGEPVEKGLYRIQ 183

Query: 156 SLEEKPKQ-PKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVEL 214
            + EKPKQ P S++A  G Y +   +    + ++    GE+++T   +  L A  +  +L
Sbjct: 184 DIVEKPKQNPPSHFAAAGRYIFTPDIFNELEALEADSGGEVQVTDAIKASLGACTVYGKL 243

Query: 215 L 215
           L
Sbjct: 244 L 244


>UniRef50_Q1LK18 UDP-glucose pyrophosphorylase n=21 Tax=Proteobacteria
           RepID=Q1LK18_RALME
          Length = 299

 Score = 81.6 bits (200), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 61/242 (25%), Positives = 105/242 (43%), Gaps = 42/242 (17%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K +    G GTR  P T+   K++LP+ DKP+I Y +   M AGI E++ +T     G  
Sbjct: 7   KAVFPVAGLGTRFLPATKASPKEMLPVVDKPLIQYAVEEAMAAGITEMIFVT-----GRS 61

Query: 62  QRLLGDGSEFGIQLE--------------------------YAEQPSPDGLAQAFIIGET 95
           +R + D  +   +LE                          Y  QP   GL  A +    
Sbjct: 62  KRAIEDHFDKAYELEAELEAKNKQALLDVVRSIKPANVECYYVRQPEALGLGHAVLCAAK 121

Query: 96  FLNGEPSCLVLGDNIFFGQGFSPKLRHVAA--RTEGATVFGYQVMDPER---FGVV---E 147
            +   P  ++L D++  G    P ++ +         +V G + + PE+   +GV+   E
Sbjct: 122 LVGDTPFAVMLADDLLDGGKDLPVMKQMVDIYNHYNCSVLGVEEIAPEQSRSYGVIDGRE 181

Query: 148 FDD---NFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMY 204
           +DD      AI  +  P++  SN  V G Y    ++ ++ +++KP   GE+++T   Q  
Sbjct: 182 WDDRVIKMSAIVEKPAPEKAPSNLGVVGRYILTPRIFDHIRELKPGAGGEIQLTDAIQSM 241

Query: 205 LE 206
           L+
Sbjct: 242 LD 243


>UniRef50_A5N939 Predicted glucose-1-phosphate nucleotidyltransferase containing an
           additional conserved domain n=5 Tax=Clostridium
           RepID=A5N939_CLOK5
          Length = 814

 Score = 81.6 bits (200), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 58/188 (30%), Positives = 93/188 (49%), Gaps = 11/188 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREI---LIITTPED 57
           MK +I+AGG GTRL P+T  + K ++P+  KP++ Y L +L   GI +I   L     E 
Sbjct: 1   MKAVIMAGGEGTRLRPLTCNIPKPMMPVMGKPIMEYALELLKNTGIEDIGATLQYLPDEI 60

Query: 58  KGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
             YF    GDG +FG+ + Y  + +P G A +    E FLN   + +V+  +       S
Sbjct: 61  INYF----GDGRDFGVNISYFVEETPLGTAGSVKNAEAFLND--TFIVISGDALTDIDLS 114

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYF 175
             + +  ++   AT+   +   P  FGVV  DD  +     EKP   +  S+   TG+Y 
Sbjct: 115 RAISYHKSKGAVATLVLKEEPVPLEFGVVVTDDKGKVTGFLEKPGWGEVFSDKVNTGIYI 174

Query: 176 YDSKVVEY 183
            + ++ +Y
Sbjct: 175 LEPEIFKY 182


>UniRef50_A9A224 Nucleotidyl transferase n=3 Tax=Thaumarchaeota RepID=A9A224_NITMS
          Length = 238

 Score = 81.6 bits (200), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 66/236 (27%), Positives = 115/236 (48%), Gaps = 15/236 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +K +ILAGG GTRL P+T    K +LP+  KP++ + +      G++ I++  +   K  
Sbjct: 4   VKAVILAGGLGTRLRPLTLKTPKPMLPLGKKPILEHLIDWNKRNGVKSIVLCVSYR-KEK 62

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK- 119
            Q    DG +FG+ +EYA    P   A      E F+N    C V GD+IF    FS K 
Sbjct: 63  IQDYFKDGKKFGVNIEYAVSKKPLATAGQLKTAEDFINDTFVC-VYGDSIF---DFSLKN 118

Query: 120 -LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDS 178
            ++   ++    T+  Y+     ++GV+      +  + EEKP + K+N  + G Y  + 
Sbjct: 119 MIKQHKSKKAFTTMSLYEYKTNLQYGVINTTKTGKVTNWEEKP-EIKANINM-GCYVMEP 176

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
            V++Y  + KP    ++   ++    + +G +T     +GF  +D G  +S  +A+
Sbjct: 177 NVLKYIPKNKPYGMDDVIKKAMKNKKMISGFIT----KKGF--MDIGNKESYKQAN 226


>UniRef50_UPI0001912073 TDP-glucose pyrophosphorylase n=1 Tax=Salmonella enterica subsp.
           enterica serovar Typhi str. AG3 RepID=UPI0001912073
          Length = 86

 Score = 81.3 bits (199), Expect = 3e-14,   Method: Composition-based stats.
 Identities = 36/69 (52%), Positives = 49/69 (71%)

Query: 216 GRGFAWLDTGTHDSLIEASTFVQTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAK 275
           GRG+AWLDTGTH SLIEAS F+ T+E+RQG K++C EEIA+R  +++ + V + A  L+K
Sbjct: 7   GRGYAWLDTGTHQSLIEASNFIATIEERQGLKVSCPEEIAFRKNFINAQQVIKLAGPLSK 66

Query: 276 TGYGQYLLE 284
               Q   E
Sbjct: 67  NRLRQIFAE 75


>UniRef50_B9LW43 Nucleotidyl transferase n=5 Tax=Halobacteriaceae RepID=B9LW43_HALLT
          Length = 402

 Score = 81.3 bits (199), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 68/239 (28%), Positives = 105/239 (43%), Gaps = 10/239 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M G++LA G GTR+ P+T    K LLP+ D+ ++     V   A       +     +G 
Sbjct: 1   MYGVVLAAGRGTRMRPLTDRRPKPLLPVGDRSLLE---QVFDTAVDVVDEFVVVTGYRGD 57

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
             R     S     + Y EQ    G A A       ++ +   LVL  ++         L
Sbjct: 58  AIRESIGESYRDRPVTYVEQEEAKGTAHAIAQAAPVVDDD--FLVLNGDVVV----DASL 111

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
             V A  +G  V   +V+DP  +GV+    +     + EKP  P +N A  G Y +  +V
Sbjct: 112 PRVLANADGPAVAATEVIDPRAYGVLSTAADGSLTKIVEKPANPPTNLANVGCYAFTPEV 171

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
            EY  +   SERGE EIT+  ++ L+ G+  +++      WLD G    L+EA+    T
Sbjct: 172 FEYIDRTPESERGEYEITTTIELLLDDGH-RIDVAPYVGTWLDVGRPWELLEANELALT 229


>UniRef50_C0ZG53 Probable mannose-1-phosphate guanyltransferase n=1
           Tax=Brevibacillus brevis NBRC 100599 RepID=C0ZG53_BREBN
          Length = 801

 Score = 81.3 bits (199), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 59/188 (31%), Positives = 92/188 (48%), Gaps = 5/188 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +I+AGG GTRL P+T    K ++P+ ++P + Y + +L   GI EI  +T       
Sbjct: 1   MKAVIMAGGKGTRLRPLTCHTPKPMVPLLNRPCMEYTIDLLKKHGITEI-AVTLQYLPDV 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDGS +G+ L Y E+  P G A +      FL+ E   ++ GD +      S  +
Sbjct: 60  IRDTFGDGSRYGVSLVYFEEAIPLGTAGSVKNCADFLD-ERFVVISGDTL-TDIDLSAAI 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPK--SNWAVTGLYFYDS 178
           R        AT+   +V  P  FGVV  D+  R     EKP   +  S+   TG+Y  + 
Sbjct: 118 RFHEQNNALATLILTRVETPLEFGVVMTDEGGRITRFLEKPSWAEVFSDTVNTGIYVCEP 177

Query: 179 KVVEYAKQ 186
           +V+ Y ++
Sbjct: 178 EVLSYIEE 185


>UniRef50_C8W233 Nucleotidyl transferase n=1 Tax=Desulfotomaculum acetoxidans DSM
           771 RepID=C8W233_DESAS
          Length = 830

 Score = 81.3 bits (199), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 60/191 (31%), Positives = 96/191 (50%), Gaps = 11/191 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIIT--TPED- 57
           MK II+AGG G+RL P+T G  K ++P+ +KP++ + + +L   GI +I +     PE  
Sbjct: 3   MKAIIMAGGEGSRLRPLTCGRPKPMVPVLNKPVMCHIIDLLKQHGITDIGVTLQYMPEAI 62

Query: 58  KGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
           K YF    G GS+FG+ + Y  + SP G A +      FL  + + LV+  +       S
Sbjct: 63  KDYF----GSGSQFGVNISYFVEESPLGTAGSVKNAGNFL--DETFLVISGDALTDLNLS 116

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYF 175
             +     +   AT+   +V  P  +GVV  ++N R     EKP   +  S+   TG+Y 
Sbjct: 117 KAIEFHRNQCSDATILLTRVDCPLEYGVVITEENGRIRRFLEKPSWGEVFSDTVNTGIYI 176

Query: 176 YDSKVVEYAKQ 186
            +  V++Y  Q
Sbjct: 177 LEPGVLDYFNQ 187


>UniRef50_Q1MRX7 UDP-glucose pyrophosphorylase n=12 Tax=Desulfovibrionales
           RepID=Q1MRX7_LAWIP
          Length = 306

 Score = 81.3 bits (199), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 64/257 (24%), Positives = 120/257 (46%), Gaps = 37/257 (14%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITT------- 54
           K ++   G GTR  P ++ + K++LPIY+KP++ Y +   MLAG+++++ +T        
Sbjct: 19  KVVVPVAGWGTRSLPASKNIPKEMLPIYNKPVVQYVVEEAMLAGVQDVIFVTNRDKSVIE 78

Query: 55  ------PEDKGYFQR--------LLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGE 100
                 P+ +   +R        ++ + +E  + +    Q    GL  A +  +  +  E
Sbjct: 79  DFFDYNPQLESILERSGKYELLKVIQNVAEM-VNIMSVRQKRQLGLGHAVLCAKEIVRDE 137

Query: 101 PSCLVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQVMDPE----RFGVVE----FDDNF 152
           P  +++GD++ FG+          AR +   V G + + PE    R+G++       D +
Sbjct: 138 PFAVMVGDDLMFGENAGMDRLIQIAREQNKPVIGVREV-PEDKINRYGIISGTEISTDVY 196

Query: 153 RAISLEEKPK--QPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEIT-SINQMYLEAGN 209
               + EKP     +S  A+ G Y     + EY ++V P   GE+++T ++  +  E G 
Sbjct: 197 DITEMIEKPTLGSTQSRLAIVGRYLLTPDIFEYLEKVTPGHGGEIQLTDALAALAQEKGM 256

Query: 210 LTVELLGRGF---AWLD 223
           L V+L G  F    W+D
Sbjct: 257 LAVKLGGLRFDAGDWVD 273


>UniRef50_C0G2T6 Nucleotidyl transferase n=1 Tax=Natrialba magadii ATCC 43099
           RepID=C0G2T6_NATMA
          Length = 417

 Score = 81.3 bits (199), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 63/228 (27%), Positives = 108/228 (47%), Gaps = 15/228 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +  ++LA G G RL P+T    K ++P+ ++P++ Y +S L  AGI  I+++      GY
Sbjct: 32  VPAVVLAAGEGRRLDPLTNRRPKPMVPVANRPILDYVVSALAGAGIDRIVLVV-----GY 86

Query: 61  FQRLL----GDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGF 116
            Q  +    GDG ++ + +EY  Q +  G A A +  E  ++G P  ++ GD I      
Sbjct: 87  RQERIRNYFGDGDDWDVDIEYVVQETQLGTAHAVLQAEEVVDG-PFLVLNGDRIVDPALV 145

Query: 117 SPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQP-KSNWAVTGLYF 175
           S     VA   +   +   +      +GVV  + N R   + EKP  P +S     G+Y 
Sbjct: 146 SQVRDAVATDADRPVLSVTRSAHASDYGVVSLEGN-RVTGITEKPIAPARSELINAGVYG 204

Query: 176 YDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLD 223
           + + + E  ++  P+E GEL IT+  +  L   + +   +     WLD
Sbjct: 205 FANDIFEAIRE-TPTEEGELAITTTLETIL--ADRSASAVQEHDIWLD 249


>UniRef50_A8M980 Glucose-1-phosphate thymidyltransferase n=3 Tax=Thermoproteaceae
           RepID=A8M980_CALMQ
          Length = 353

 Score = 80.9 bits (198), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 77/243 (31%), Positives = 111/243 (45%), Gaps = 22/243 (9%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M G+IL  G G R+ P++  + K L+ I  KP++ Y +  L    +  I ++      G 
Sbjct: 1   MLGLILVAGIGERMRPLSYSIPKPLISILGKPLVAYTMDKLKDIDVSRIGLVV-----GR 55

Query: 61  FQRLLGD----GSEFGIQLEYAEQPSPDGLAQAFIIG--ETFLNGEPSCLVLGDNIFFGQ 114
           F  L  D         I + Y  Q    G+A A   G  E FL  E   + LGDN +F +
Sbjct: 56  FSELFMDYFNNDPRLNIPVTYIRQERRLGIAHAIYRGIEEGFLR-EDFVVALGDN-YFSE 113

Query: 115 GFSPKLRHVAARTEGATVFGYQVMDPERFG--VVEFDDNFRAISLEEKPKQPKSN-WAVT 171
            F+   R          +   +    +RFG  VVE     R + L EKP QP  N + VT
Sbjct: 114 SFTRFAREFLEGGYDVFIVLTRHQQFQRFGNAVVE---GGRVVRLIEKPNQPIPNSYVVT 170

Query: 172 GLYFY-DSKVVEYA-KQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDS 229
           GLYF+ D   V  A   ++PS RGE E+T + Q +++        L  G+ W D GT + 
Sbjct: 171 GLYFFRDPDAVAKAFSNLRPSARGEYEVTDLIQWFIDNNYRVGYSLTTGW-WKDMGTPED 229

Query: 230 LIE 232
           LI+
Sbjct: 230 LID 232


>UniRef50_C0GV25 dTDP-glucose pyrophosphorylase-like protein n=1
           Tax=Desulfonatronospira thiodismutans ASO3-1
           RepID=C0GV25_9DELT
          Length = 85

 Score = 80.9 bits (198), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 35/50 (70%), Positives = 42/50 (84%)

Query: 237 VQTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELL 286
           V+T+EKRQG+KIACLEEIAWRNGWL D+ ++  A S+ K GYGQYLL LL
Sbjct: 34  VETIEKRQGYKIACLEEIAWRNGWLTDQELENTARSMGKNGYGQYLLALL 83


>UniRef50_C3MRT7 Nucleotidyl transferase n=12 Tax=Sulfolobaceae RepID=C3MRT7_SULIM
          Length = 253

 Score = 80.9 bits (198), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 64/252 (25%), Positives = 104/252 (41%), Gaps = 24/252 (9%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIY--------DKPMIYYPLSVLMLAGIREILIIT 53
           K +I + G G+R+  IT  + K LLP++         +P+I   +  L   GI +  I+ 
Sbjct: 4   KAVITSAGKGSRMKHITSVLPKALLPLFVTENGGKVTRPVIDLIMDSLNKVGIEKFCIVV 63

Query: 54  TPEDKGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFG 113
                   Q L      F  Q        P G   A +  E F + EP   V  D+    
Sbjct: 64  GRNGMLLMQYLFDRTPTFVFQ------DMPKGFGDAVLRAEDFSSNEP-FFVHADDGVLT 116

Query: 114 QGFSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDN--------FRAISLEEKPKQPK 165
           +G+          +  A +F  +V +P R+GVV   D         ++ I  EEKP  PK
Sbjct: 117 KGYESLKLLFDEVSPDAVLFVRRVENPSRYGVVTIQDKGVYDGHKLYKVIDAEEKPLHPK 176

Query: 166 SNWAVTGLYFYDSKVVEYAKQVKPSERGELEIT-SINQMYLEAGNLTVELLGRGFAWLDT 224
           SN A+  +Y +   +    KQ+   E  E+E+T  I+ + L+   +    +     WL+ 
Sbjct: 177 SNLAIAAVYIFKPSIFSALKQINVEEGKEIELTYGIHNLLLDGKEVYALEMNEDEKWLNV 236

Query: 225 GTHDSLIEASTF 236
           G   S ++A  +
Sbjct: 237 GDPKSYLDALNY 248


>UniRef50_Q49VP4 UTP--glucose-1-phosphate uridylyltransferase 2 n=216 Tax=cellular
           organisms RepID=GTAB2_STAS1
          Length = 289

 Score = 80.5 bits (197), Expect = 6e-14,   Method: Compositional matrix adjust.
 Identities = 79/283 (27%), Positives = 117/283 (41%), Gaps = 59/283 (20%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K II A G GTR  P T+ + K++LPI DKP I Y +     AGI +I+I+T     G  
Sbjct: 6   KAIIPAAGLGTRFLPATKAMPKEMLPILDKPTIQYIVEEAARAGIEDIIIVT-----GKH 60

Query: 62  QRLLGDGSEFGIQLE-------------------------YAEQPSPDGLAQAFIIGETF 96
           +R + D  +   +LE                         Y  Q    GL  A      F
Sbjct: 61  KRAIEDHFDNQKELEMILQEKGKTDLLEKVKYSTELANIFYVRQKEQKGLGHAIYSARQF 120

Query: 97  LNGEPSCLVLGDNIFFGQGFSPKLRHV--AARTEGATVFGYQVMD---PERFGVVE---- 147
           +  EP  ++LGD+I   +  +P ++ +  A    G +V G Q +D     R+G+++    
Sbjct: 121 IGDEPFAVLLGDDIV--ESDNPAIKQLIEAYEETGKSVIGVQEVDEAQTHRYGIIDPLQK 178

Query: 148 FDDNFRAISLEEKPKQ--PKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITS------ 199
           F   +      EKPKQ    SN A+ G Y     + +Y         GE+++T       
Sbjct: 179 FGRKYEVNEFVEKPKQGTAPSNLAIMGRYVLTPDIFDYLATQGEGAGGEIQLTDAIERLN 238

Query: 200 -INQMY---LEAGNLTV-ELLG-----RGFAWLDTGTHDSLIE 232
             +Q+Y    E     V E LG       +A  D   HD L+E
Sbjct: 239 RADQVYAYDFEGDRYDVGEKLGFVKTTIEYALKDESMHDELVE 281


>UniRef50_A6Q9R9 Mannose-1-phosphate guanylyltransferase n=3 Tax=Bacteria
           RepID=A6Q9R9_SULNB
          Length = 840

 Score = 80.1 bits (196), Expect = 8e-14,   Method: Compositional matrix adjust.
 Identities = 65/237 (27%), Positives = 111/237 (46%), Gaps = 14/237 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIIT--TPEDK 58
           +K +++AGG GTR+ P+T  + K +LPI + PM+ + +  L+  GI EI+++    PE  
Sbjct: 5   IKAVMMAGGFGTRIQPLTHSMPKPMLPICNIPMMEHTMRKLVDIGITEIVVLLYFKPE-- 62

Query: 59  GYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSP 118
              +   GDGS  G++LEY       G A A      FL  + + +++  ++     F  
Sbjct: 63  -IIKNHFGDGSRIGVKLEYVLPEEDLGTAGAVGAAREFL--DTTFIIVSGDLVSDFDFEK 119

Query: 119 KLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFY 176
            + H        T+    V +P +FGVV  D+N +     EKP   +  S+   TG+Y  
Sbjct: 120 IIDHHYKTESKLTITLTSVENPLQFGVVIADENGKIEKFLEKPSWGEVFSDTINTGIYVI 179

Query: 177 DSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEA 233
           + ++++Y     P+E        +  + +  G   +    RG+ W D G  DS  E 
Sbjct: 180 EPEILDYI----PTEDNFDFAKDLFPLLMSEGIDLMSYDARGY-WRDVGNPDSYREV 231


>UniRef50_A3DED2 Nucleotidyl transferase n=8 Tax=Clostridium RepID=A3DED2_CLOTH
          Length = 820

 Score = 80.1 bits (196), Expect = 8e-14,   Method: Compositional matrix adjust.
 Identities = 59/188 (31%), Positives = 95/188 (50%), Gaps = 11/188 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITT--PE-D 57
           MK +I+AGG GTRL P+T    K ++P+ +KP++ + + +L   G  +I +     P+  
Sbjct: 1   MKAVIMAGGEGTRLRPLTCNRPKPMVPVVNKPVMEHIIELLKKHGFTDIAVTLQYLPDMI 60

Query: 58  KGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
           K YF    GDGS+FGI L Y  +  P G A +    E FL  + + LV+  +        
Sbjct: 61  KDYF----GDGSDFGINLRYYVEDKPMGTAGSVKNAEEFL--DDTFLVISGDALTDIDLG 114

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYF 175
             + +  ++   AT+   +V  P  +GVV  D+N R     EKP   +  S+   TG+Y 
Sbjct: 115 KAVEYHYSKGSMATLVLKKVDIPLEYGVVVTDENGRITRFLEKPSWGEVFSDTVNTGIYI 174

Query: 176 YDSKVVEY 183
              +V++Y
Sbjct: 175 LSPEVLKY 182


>UniRef50_Q58730 Putative UTP--glucose-1-phosphate uridylyltransferase n=6
           Tax=cellular organisms RepID=Y1334_METJA
          Length = 283

 Score = 80.1 bits (196), Expect = 9e-14,   Method: Compositional matrix adjust.
 Identities = 66/263 (25%), Positives = 120/263 (45%), Gaps = 40/263 (15%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTP------ 55
           K +I   G GTRL PIT+   K++LP+ +KP++ Y +  L+ AG+++IL +T        
Sbjct: 4   KAVIPVAGFGTRLLPITKAQPKEMLPVVNKPIVQYVVEDLVEAGVKDILFVTGKGKQAIE 63

Query: 56  -------------EDKGYFQ--RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGE 100
                        E  G ++  +++ +    G  + Y  Q    GL  A + GE F+  E
Sbjct: 64  NHFDVNYELECKLEKSGKYELLKIIKEIDRLG-NIFYVRQKEQKGLGDAILYGEEFVGEE 122

Query: 101 PSCLVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQVMDPE---RFGVVEFDD----NFR 153
               ++GD I+        ++  A    G +V   + +  E   ++GV++ ++     ++
Sbjct: 123 YFIAMVGDTIYSKNIVKDLIK--AHEKYGCSVIALERVPKEDVYKYGVIDGEEIEKGVYK 180

Query: 154 AISLEEKPK--QPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEIT-SINQMYLEAGNL 210
             ++ EKPK  +  SN  +TG Y    K+ E  ++  P   GE++IT ++N +  E   +
Sbjct: 181 IKNMVEKPKVEEAPSNLIITGAYLLSPKIFEKIRETPPGRGGEIQITDAMNLLLKEEDII 240

Query: 211 TVEL------LGRGFAWLDTGTH 227
            VE+      +G    WL     
Sbjct: 241 GVEINCKRYDIGDALGWLKANVE 263


>UniRef50_A3DMT9 Nucleotidyl transferase n=11 Tax=Thermoprotei RepID=A3DMT9_STAMF
          Length = 426

 Score = 80.1 bits (196), Expect = 9e-14,   Method: Compositional matrix adjust.
 Identities = 74/242 (30%), Positives = 120/242 (49%), Gaps = 16/242 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREI--LIITTPEDK 58
           MK IILA G G RL PIT    K L+P+  KP++ + L  L  AGI E+  ++I     K
Sbjct: 2   MKAIILAAGKGLRLRPITETRPKPLIPVLCKPLLQWQLEAL--AGINEVDEVVIVVSYLK 59

Query: 59  GYFQRLLGD-GSEFGIQL--EYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQG 115
              ++ +G     F I L  +  E  + D + +A  I +  ++G+   L++  +IF  + 
Sbjct: 60  EQVEQFVGKLNMPFKITLLDQGEELGTGDAILKA--IRKRGIDGK--ILIIYGDIFL-KD 114

Query: 116 FSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYF 175
           ++   + V  R +   + G +V +P  +GV+  D+      + EKP  P SN    GLYF
Sbjct: 115 WNELKQLVLTRKD--FIVGVEVDNPSDYGVIVVDEYNSFKGIIEKPAIPPSNLINAGLYF 172

Query: 176 YDSKVVEYAKQVKPSERGELEITSI-NQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
            D++ +     ++ S RGELE T I + M      + V  L +G  W+D G    L++A+
Sbjct: 173 LDARDILKHSDIELSPRGELEFTDILSSMARNGVEIKVYQLSKG-KWIDIGKPWHLLDAN 231

Query: 235 TF 236
             
Sbjct: 232 KM 233


>UniRef50_A6UP85 Glucosamine-1-phosphate N-acetyltransferase n=6 Tax=Methanococcales
           RepID=GLMU_METVS
          Length = 414

 Score = 80.1 bits (196), Expect = 9e-14,   Method: Compositional matrix adjust.
 Identities = 67/243 (27%), Positives = 117/243 (48%), Gaps = 24/243 (9%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M  +IL  GSGTRL+PIT    K ++PI  KP++ + +  +    + +I ++   E +  
Sbjct: 1   MDAVILCAGSGTRLYPITENRPKPMIPIAGKPILEHIIEKIE-NHVEKIYLVVGFEKEKI 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                G+      ++E+  Q    G   A ++ + ++ G+   LVL  ++ F       L
Sbjct: 60  IDYFYGNE-----KIEFIVQEKQLGTGHAVLMAKNYIKGD--FLVLNGDVIFESDILEFL 112

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPK------SNWAVTGLY 174
            +  A      V   +V +PE FGV+E   + + I+L EKP + +      SN    G+Y
Sbjct: 113 NYENA------VGLSKVDNPENFGVIELGYDNKVINLLEKPNEDEIKSKFTSNLINAGIY 166

Query: 175 FYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLT-VELLGRGFAWLDTGTHDSLIEA 233
             ++ V E  + + PSERGE+E+T   +  +E+  L  +EL G    W D G    ++ A
Sbjct: 167 KLENFVFEILENLLPSERGEIELTDALKKLIESSKLYGIELNGY---WNDIGRPWDVLSA 223

Query: 234 STF 236
           + +
Sbjct: 224 NNY 226


>UniRef50_C6A0S3 Nucleotidyl transferase family n=6 Tax=Thermococcaceae
           RepID=C6A0S3_THESM
          Length = 361

 Score = 79.7 bits (195), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 60/194 (30%), Positives = 98/194 (50%), Gaps = 24/194 (12%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M  +ILAGG GTRL P+T    K ++P ++KPM+ Y +  L+ AG+ EI I+      GY
Sbjct: 1   MHAVILAGGKGTRLLPLTVYRPKPMIPFFNKPMMEYVVRELVNAGVEEIFILV-----GY 55

Query: 61  FQRLL----GDGSEFGIQLEYAEQPSPD-GLAQAFI-----IGETFLNGEPSCLVLGDNI 110
            +  +    GDGS+FG++++Y+   +   G A A       I +TF+      L    N+
Sbjct: 56  LKERIINYFGDGSDFGVEIKYSNGENIKLGTAGATKKVADRINDTFIVASSDVLT---NL 112

Query: 111 FFGQGFSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNW 168
                +    R  A     AT+   +V DP ++G+   D N R +  +EKP+  +  SN 
Sbjct: 113 DIKTLYDYHKRKKAL----ATIALSRVEDPSQYGIAIVDSNNRILKFKEKPRLEEAFSNL 168

Query: 169 AVTGLYFYDSKVVE 182
              G+Y ++ +V +
Sbjct: 169 VNAGVYIFEPEVFD 182


>UniRef50_Q74B34 Nucleotidyltransferase family protein n=1 Tax=Geobacter
           sulfurreducens RepID=Q74B34_GEOSL
          Length = 476

 Score = 79.7 bits (195), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 71/243 (29%), Positives = 111/243 (45%), Gaps = 21/243 (8%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +  +++AGG G RL P+T  V K +LP+ D+P++   +  L  +GIRE+ + T       
Sbjct: 247 LSAVVMAGGYGKRLLPLTEQVPKPMLPVGDRPLLERTIDQLRRSGIREVNLTTHYLPDSI 306

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDG  FG++L Y ++  P G A      +         LV+  +I  G  F    
Sbjct: 307 VEH-FGDGDSFGVKLNYLKEDHPLGTAGGL---KLMKKASDPFLVMNGDILTGVPFQEMF 362

Query: 121 RHVAARTEGAT----VFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFY 176
            +   R  GA     V  Y+V  P  FGVVE DD  R   L+EKP    + +   G+Y  
Sbjct: 363 AY--HRKNGAEITVGVRKYEVQVP--FGVVECDD-VRITGLKEKPSL--TFFINAGIYLL 415

Query: 177 DSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTF 236
           +  V +    +   ER   ++T + Q  L+ G   V      + WLD G H+   +A   
Sbjct: 416 EPSVCDL---IPEGER--FDMTDLIQKLLDEGRSVVSFPIMEY-WLDVGRHEDYQKAQED 469

Query: 237 VQT 239
           V++
Sbjct: 470 VRS 472


>UniRef50_B8D5T2 Putative sugar-phosphate nucleotidyl transferase n=2
           Tax=Thermoprotei RepID=B8D5T2_DESK1
          Length = 283

 Score = 79.7 bits (195), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 68/242 (28%), Positives = 108/242 (44%), Gaps = 15/242 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M  +ILAGG G RL P T  V K ++P+ DKP++ + +  L   G REI+++     +  
Sbjct: 43  MLAVILAGGYGKRLRPYTDDVPKPMIPVGDKPILEWQIEWLKKYGFREIVLLVGYRKEKI 102

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  +G GS  G+++ Y  +  P G   A    E  L+   + LV+  +I      +P  
Sbjct: 103 IE-YIGSGSRLGVRVTYVVEDEPLGTGGAIKNAEHVLSRNGTFLVINGDII--TNLNP-- 157

Query: 121 RHVAARTEGATVFGY--QVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDS 178
             +  + EG+   G    +  P  +GV+E +D  R     EKP Q    W   G+Y  + 
Sbjct: 158 LKLVEKLEGSRYLGVIASIPLPSPYGVLEIEDEDRVKGFVEKP-QLSDYWINAGVYALNP 216

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           + + Y       E+G+LE T+   M  +    TV     G  W    T   L EAS  + 
Sbjct: 217 EALRYF-----PEKGDLEKTAFPAMARDGVLGTVRY--TGVFWKAIDTFKELEEASRAIH 269

Query: 239 TV 240
            +
Sbjct: 270 EI 271


>UniRef50_UPI00016B2344 UTP-glucose-1-phosphate uridylyltransferase n=3 Tax=candidate
           division TM7 RepID=UPI00016B2344
          Length = 270

 Score = 79.7 bits (195), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 77/266 (28%), Positives = 120/266 (45%), Gaps = 32/266 (12%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDK--- 58
           K IILA G GTR  PIT+ V K +LPI ++P+I Y +   +LAGI++I  +   ED    
Sbjct: 4   KAIILAAGWGTRRLPITKSVEKCMLPIGNRPVIDYVVQDAILAGIKDIYFVVNSEDNQIE 63

Query: 59  ----------------GYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETF---LNG 99
                           G  + L       G+   + EQ        A  +G  F     G
Sbjct: 64  KYYKPYPKLEQYLNFAGKPEYLRYIAPPQGVNFYFIEQEVNTKYGTAIPVGLCFPYIRPG 123

Query: 100 EPSCLVLGDNIFFGQGFSPKLRHVAART-EGATVFGYQVMDPER---FGVVEFDD--NFR 153
           E   ++ GD+  +    S +L  +  +T +GA+      +DP R   +GV+EFD   N+ 
Sbjct: 124 ESVAVLTGDDFIYNYDGSSELARLIMQTPQGASSMLSVEVDPNRVGEYGVIEFDTQGNYY 183

Query: 154 AISLEEKPKQPKSNWAVTGLYFYDSKVVEYAKQV-KPSERGELEITS-INQMYLEAGNLT 211
            I  +  P+   SN+     Y  + +V++ A    K    GE  +T  INQ  L  G + 
Sbjct: 184 QIVEKPSPENSPSNYINISKYILNYEVLQAAAAYSKVDITGEYALTEPINQYVLTGGTMK 243

Query: 212 VELLGRGFAWLDTGTHDSLIEASTFV 237
           V +L +G  + D+G   + +EA+  V
Sbjct: 244 V-VLSQG-KYFDSGNAYAWVEANRTV 267


>UniRef50_C7NR86 Nucleotidyl transferase n=4 Tax=Halobacteriaceae RepID=C7NR86_HALUD
          Length = 439

 Score = 79.3 bits (194), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 66/234 (28%), Positives = 108/234 (46%), Gaps = 14/234 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +ILA G GTR+ P+T    K +LP+  +P++ +     + AG  E++++   E +  
Sbjct: 47  MQTVILAAGQGTRMGPLTESTPKPMLPVAGRPLVAHVADAAVDAGASELVVVVGYEAEA- 105

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GD +   + + +A Q    G A A       L+G  + L  GDN++         
Sbjct: 106 VRSFFGD-TYRDVPVTFAVQAEQAGTADAVRAARPELDGAFAVL-NGDNLYDPAAVEQLF 163

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                     ++  Y+V DP  +GVV   D      + EKP  P + +A TG Y +    
Sbjct: 164 E------SAPSLATYEVDDPSNYGVVSITDGI-VTDIVEKPADPPTTYANTGAYVFPEAA 216

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
           +++   V  SERGE EIT +    ++A  +T   L R   W D G    L+EA+
Sbjct: 217 IDWL-DVPESERGEYEITDVVAQVIDAHEVTPVPLSR---WRDVGRPWELLEAN 266


>UniRef50_Q0RC10 UTP--glucose-1-phosphate uridylyltransferase (UDP-glucose
           pyrophosphorylase) (UDPGP) (Alpha-D-glucosyl-1-phosphate
           uridylyltransferase) (Uridine diphosphoglucose
           pyrophosphorylase) (General stress protein 33) (GSP33)
           n=7 Tax=Bacteria RepID=Q0RC10_FRAAA
          Length = 310

 Score = 79.3 bits (194), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 67/233 (28%), Positives = 108/233 (46%), Gaps = 35/233 (15%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKG-- 59
           K +I A G GTR  P T+ V K++LP+ D+P I Y +      G+R++L++T+   K   
Sbjct: 5   KAVIPAAGLGTRFLPATKAVPKEMLPVVDRPAIEYVVEEASRVGLRDVLLVTSRTKKAIE 64

Query: 60  -YFQR-------LLGDGSEFGIQ-----LEYAE-----QPSPDGLAQAFIIGETFLNGEP 101
            +F R       L   G E  ++      E AE     QPSP GL  A +     +  EP
Sbjct: 65  DHFDREADIEAALERKGDETRLRRVRASAELAEVHSVRQPSPRGLGHAILCAAAHVGDEP 124

Query: 102 SCLVLGDNIFFGQG-FSPKLRHVAARTEGATVFGYQVMDPE--RFGVVEF-------DDN 151
             ++LGD++   +     ++  V AR  G+ +   +V   +   +GV          DD 
Sbjct: 125 FAVLLGDDLIDERDPLLAEMLAVQARFGGSVIALMEVPREQVSMYGVATVESVPTGPDDR 184

Query: 152 F---RAISLEEKP--KQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITS 199
           +   R + L EKP   +  SN A+ G Y    ++ E  ++ +P   GE++IT 
Sbjct: 185 YGIVRILDLVEKPPVAEAPSNLAIIGRYVLAPEIFEVLRRTEPGRGGEIQITD 237


>UniRef50_B7J1D8 UDP-glucose pyrophosphorylase n=21 Tax=Borrelia RepID=B7J1D8_BORBZ
          Length = 313

 Score = 79.0 bits (193), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 73/261 (27%), Positives = 128/261 (49%), Gaps = 34/261 (13%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDK-- 58
           MKGIILA G GTR  PIT+ + K++LPI +KP I Y +   + +GI++IL+I++   K  
Sbjct: 36  MKGIILAAGYGTRFLPITKTIPKEMLPILNKPAIDYIIQEFIDSGIKDILLISSRRKKVL 95

Query: 59  -GYFQRLLGDGSEF---------------GIQLEYAEQPSPDGLAQAFIIGETFLNGEPS 102
             YF R +   + F                I + +  Q    G   A +  + ++N EP 
Sbjct: 96  EDYFDREIELENIFLKENKKDELEKIRSKKINISFIRQKEMLGTGNALLYAKPWINREPV 155

Query: 103 CLVLGDNIFFGQ-GFSPKLRHVAARTEGATVFGYQVMDPE---RFGVVE-FDDNFRAISL 157
            +   D++  G    S +L  +  +T G  +    + +PE   R+GV++ + D     ++
Sbjct: 156 VVAYPDDLCIGNPPLSLQLIKLYEKT-GKNIISI-IENPENINRYGVIDLYKDEIHVKNI 213

Query: 158 EEKPK---QPKSNWAVTGLYFYDSKVVEYAKQ-VKPSERGE-LEITSINQMYLEAGNLTV 212
            EKPK   +P SN A  G + Y+ +  E+ ++  K  ++GE   I ++ ++  +   L  
Sbjct: 214 IEKPKIGSEP-SNKASIGRFLYNYEFFEHLEEGFKLHKKGEYYHIYALKKLMDQKKVLYK 272

Query: 213 ELLGRGFAWLDTGTHDSLIEA 233
            + G+    +D GT +  +EA
Sbjct: 273 NIEGK---RIDIGTLEGYLEA 290


>UniRef50_Q3Z778 Nucleotidyltransferase family protein n=5 Tax=Dehalococcoides
           RepID=Q3Z778_DEHE1
          Length = 361

 Score = 79.0 bits (193), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 55/185 (29%), Positives = 88/185 (47%), Gaps = 5/185 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK IIL GG GTRL P++    K ++P+ + P + + L  L   GI++I I+T       
Sbjct: 1   MKAIILVGGQGTRLRPLSINTPKSMVPVLNVPFLSHVLRYLSSCGIKDI-ILTQGHLAAP 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            ++  G+G   G+ L Y+ +    G A A    E +L  + + + L  +IF     S  L
Sbjct: 60  IEQYFGNGQSLGVNLVYSVEHEALGTAGAIKNAERYL--DDTFITLNGDIFTHLDLSAML 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
           R    +    ++    V DP ++G+VE  D  R     EKP   Q  +N    G Y  + 
Sbjct: 118 RAHRDKKALVSIALTPVDDPTKYGLVETADGGRVSRFLEKPSPAQITTNMINAGTYIIEP 177

Query: 179 KVVEY 183
           +V++Y
Sbjct: 178 EVLKY 182


>UniRef50_D1B9X0 UTP-glucose-1-phosphate uridylyltransferase n=1
           Tax=Thermanaerovibrio acidaminovorans DSM 6589
           RepID=D1B9X0_THEAS
          Length = 293

 Score = 79.0 bits (193), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 63/220 (28%), Positives = 105/220 (47%), Gaps = 29/220 (13%)

Query: 9   GSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIIT-------------TP 55
           G GTR  P T+   K++LP+ D+P+I+Y +     AG R+++ +T             +P
Sbjct: 17  GLGTRFLPATKETPKEMLPLIDRPLIHYGVEEACGAGCRDVVFVTGRGKRSIEDYFDRSP 76

Query: 56  EDKGYFQ-RLLGDGSEF--GI----QLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGD 108
           + +G  + R   D +E   GI    +  Y  Q  P GL  A + G T  NG+   ++L D
Sbjct: 77  DLEGLLETRGKLDLAEMVRGISEMARFSYVRQSEPLGLGHAVLCGRTCCNGDHFGVILPD 136

Query: 109 NIFFGQ-GFSPKLRHVAARTEGATVFGYQVM--DPERFGVVEFDD----NFRAISLEEK- 160
           ++         +L  V  R  G+ +   +V   D  R+G+V+ +D     FR   L EK 
Sbjct: 137 DVILSHVPVLAQLDQVRLRFGGSVLALEEVSEEDTSRYGIVDAEDLGGGVFRIRDLVEKP 196

Query: 161 -PKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITS 199
            PK   S  A+ G Y   S++ ++ ++V P   GE+++T 
Sbjct: 197 DPKDAPSRLAIMGRYVLSSRIFDHLERVLPGSGGEIQLTD 236


>UniRef50_B0BZX4 Phosphoglucomutase/phosphomannomutase family Nucleotidyl
           transferase n=23 Tax=Bacteria RepID=B0BZX4_ACAM1
          Length = 844

 Score = 78.6 bits (192), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 68/244 (27%), Positives = 118/244 (48%), Gaps = 27/244 (11%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREIL--IITTPED- 57
           M+ +++AGG GTRL P+T  + K ++PI ++P+  + +++L    I EI+  +   P+  
Sbjct: 1   MRAVLMAGGEGTRLRPLTCDLPKPMVPILNRPIAEHIVNLLKHHQIYEIIATLYYLPDVM 60

Query: 58  KGYFQRLLGDGSEFGIQLEYA-EQPSPDGLAQAF-----IIGETFLNGEPSCLVLGDNIF 111
           + YF+    DGS+FG+Q+ Y  E+    G A        ++ +TFL     C+   D   
Sbjct: 61  RDYFR----DGSDFGVQMTYGIEEEQALGTAGCVKNISALLTDTFLVISGDCITDFD--- 113

Query: 112 FGQGFSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPK--SNWA 169
                +  ++    +   AT+   +V DP  FGVV  D + +     EKP   +  S+  
Sbjct: 114 ----LTAAIKFHRQKGSKATLVLARVPDPMEFGVVITDQSHQICRFLEKPSTSEVFSDTV 169

Query: 170 VTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDS 229
            TG+Y  + +V++Y     PS++       +  + LE G      +  G+ W D G+ DS
Sbjct: 170 NTGIYILEPEVLDYL----PSDQQTDFSKDLFPLLLEKGEPMFGYVAEGY-WCDVGSLDS 224

Query: 230 LIEA 233
             EA
Sbjct: 225 YREA 228


>UniRef50_Q12TW4 Mannose-1-phosphate guanyltransferase n=11 Tax=Euryarchaeota
           RepID=Q12TW4_METBU
          Length = 399

 Score = 78.6 bits (192), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 58/189 (30%), Positives = 84/189 (44%), Gaps = 12/189 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK  I+ GG GTRL P+T    K  +PI +KP + + +  L   G  EI+I       GY
Sbjct: 14  MKACIMCGGEGTRLRPLTFERPKPSIPILNKPSVVHLVEHLAKEGFTEIVITI-----GY 68

Query: 61  F----QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGF 116
                +  LGDG  +G+ +EY  +    G A      E FL  EP  +V GD++      
Sbjct: 69  MAEKIEECLGDGRMYGVYIEYVYEEKRLGTAGGVKNAEEFLKDEPFMIVGGDHV-MDLSL 127

Query: 117 SPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPK--SNWAVTGLY 174
               R         T+    + DP  FG+ + D N R     EKP   +  SN A TG+Y
Sbjct: 128 RSIYRQHEMNDAMITIGLMSIDDPREFGIADMDVNNRIHRFLEKPGPGEIFSNLASTGIY 187

Query: 175 FYDSKVVEY 183
               ++ ++
Sbjct: 188 MCSPEIFDW 196


>UniRef50_A7AUL2 Mannose-1-phosphate guanyltransferase, putative n=1 Tax=Babesia
           bovis RepID=A7AUL2_BABBO
          Length = 417

 Score = 78.2 bits (191), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 48/187 (25%), Positives = 85/187 (45%), Gaps = 4/187 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +ILAGG GTRL P+T  V K ++P  ++P++ Y +     AG+  I++  + E    
Sbjct: 1   MKCVILAGGHGTRLRPLTLTVPKPMIPFCNRPIVEYQIKASKEAGVDHIILAISHEQNNM 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFL-NGEPSC---LVLGDNIFFGQGF 116
              +        I+++ + +    G A    + +  + +   +C   LVL  +I     F
Sbjct: 61  VPMIKELSERCNIRIDCSIEKESLGTAGPLKLAKNLICDPADNCKEFLVLNSDIICSYPF 120

Query: 117 SPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFY 176
           +  +         AT+   +   P  FGV+  D+ +R     EKP Q  SN    G+Y  
Sbjct: 121 AEMISAHRKNNADATILVTKTTHPSDFGVIVHDETYRIHEFVEKPSQFISNQINAGIYVL 180

Query: 177 DSKVVEY 183
           +  +++Y
Sbjct: 181 NKNMLDY 187


>UniRef50_Q7NNE0 Mannose-1-phosphate guanyltransferase n=5 Tax=Gloeobacter violaceus
           RepID=Q7NNE0_GLOVI
          Length = 327

 Score = 78.2 bits (191), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 56/185 (30%), Positives = 90/185 (48%), Gaps = 4/185 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK  +LA G GTRL P T  + K L+P+ +KP++ + L++    G  +I+       +  
Sbjct: 1   MKAFVLAAGKGTRLRPFTDALPKPLMPVVNKPVMTHILALCRKHGFDQIVANLHYRGEKI 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +R   DG   G++L Y+ +    G A        FL G+ + LV+  ++         +
Sbjct: 61  AER-FADGHRHGVELRYSWEEQLLGTAGGVRRQADFLAGD-AFLVISGDVMTDLDLGALV 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQ--PKSNWAVTGLYFYDS 178
           R        AT+   +V DP RFGVV  D + R  S +EKP +   +S  A TG+Y  + 
Sbjct: 119 RFHKQSGAVATMAVKEVGDPSRFGVVLTDPDGRVESFQEKPAKGSERSRLANTGIYVLEP 178

Query: 179 KVVEY 183
           +V E+
Sbjct: 179 EVFEH 183


>UniRef50_A8KY05 Nucleotidyl transferase n=6 Tax=Actinomycetales RepID=A8KY05_FRASN
          Length = 843

 Score = 78.2 bits (191), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 58/189 (30%), Positives = 93/189 (49%), Gaps = 12/189 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +++AGG GTRL P+T  + K LLP+ ++P++ + L +L   G  E  ++T       
Sbjct: 1   MRAVVMAGGEGTRLRPLTANLPKPLLPVVNRPIMEHVLRLLKRHGFDET-VVTVQFLAAM 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   G G E G+ L YA + +P G A +    E  L  E   ++ GD +         L
Sbjct: 60  IRNYFGSGDELGMHLSYATETTPLGTAGSVKNAEDALRHEEFLVISGDAL-----TDIDL 114

Query: 121 RHVAA--RTEGA--TVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLY 174
             + A  R +GA  TV    V DP  FG+V   ++ R     EKP   Q  S+   TG+Y
Sbjct: 115 TDLVAYHRAQGALVTVALKSVPDPLEFGIVITGEDGRISRFLEKPTWGQVFSDTVNTGIY 174

Query: 175 FYDSKVVEY 183
             + +V+++
Sbjct: 175 VMEPEVLDH 183


>UniRef50_B2UH51 UTP-glucose-1-phosphate uridylyltransferase n=127 Tax=Bacteria
           RepID=B2UH51_RALPJ
          Length = 317

 Score = 78.2 bits (191), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 64/267 (23%), Positives = 114/267 (42%), Gaps = 38/267 (14%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIIT-------- 53
           K +    G GTR  P T+   K++LPI DKP+I Y +     AGI E++ IT        
Sbjct: 7   KAVFPVAGLGTRFLPATKASPKEMLPIVDKPLIQYAVEEAAAAGITEMIFITGRAKRAIE 66

Query: 54  -------------TPEDKGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGE 100
                          ++K     ++      G++  Y  QP   GL  A +  +  +  E
Sbjct: 67  DHFDKAYELETELAAKNKQALLDMVQSIKPAGVECFYVRQPETLGLGHAVLCAQKLVRDE 126

Query: 101 PSCLVLGDNIFFGQGFSPKLRHVAARTEG--ATVFGYQVMDPE---RFGVV---EFDD-- 150
           P  ++L D++   +   P ++ +    +    ++ G + + PE    +GVV   E+DD  
Sbjct: 127 PFAVILADDLLDHE--PPVMQQMTELYDHYRCSIVGVETIAPEATRSYGVVAGREWDDRL 184

Query: 151 -NFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEIT-SINQMYLEAG 208
                I  +  P +  SN  V G Y    ++ ++ + ++P   GEL++T +I  +  E  
Sbjct: 185 VKLDGIVEKPAPSEAPSNLGVVGRYILTPRIFDHLRNLRPGAGGELQLTDAIQSLLAEEQ 244

Query: 209 NLTVELLGRGFAWLDTGTHDSLIEAST 235
            L     G+ F   D G+    ++A+ 
Sbjct: 245 ILAYRYRGQRF---DCGSKFGYLQATV 268


>UniRef50_B9YXM9 Glucose-1-phosphate thymidylyltransferase n=1 Tax='Nostoc azollae'
           0708 RepID=B9YXM9_ANAAZ
          Length = 91

 Score = 77.8 bits (190), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 35/75 (46%), Positives = 52/75 (69%)

Query: 137 VMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELE 196
           + +P ++ V+EF+ + +AI +EEKPK PKS +AV G+YFYD +V E A  +K S R ELE
Sbjct: 1   MTEPRKYSVIEFNADGKAIRIEEKPKLPKSKYAVPGIYFYDDQVTEIAASLKRSPRNELE 60

Query: 197 ITSINQMYLEAGNLT 211
           IT +N  Y  + ++T
Sbjct: 61  ITDVNLAYFRSRSIT 75


>UniRef50_C7PVA0 Nucleotidyl transferase n=3 Tax=Bacteroidetes RepID=C7PVA0_CHIPD
          Length = 330

 Score = 77.8 bits (190), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 70/252 (27%), Positives = 114/252 (45%), Gaps = 35/252 (13%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK II   G+GT+L P T    K L+P+  + ++   +  L+ AGI E + +      GY
Sbjct: 1   MKAIIPVAGAGTKLRPHTYTQPKALIPLAGRTILSIIIDQLVEAGINEFVFVI-----GY 55

Query: 61  FQRLLGDGSEFGIQLEY-------AEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFG 113
               LGD  +  +Q +Y        +Q S +G   A ++    +  +   +VLGD I  G
Sbjct: 56  ----LGDKIQHYVQQKYPHLTCHFVQQNSREGTGHAILLTRQVVQDDEILIVLGDTICEG 111

Query: 114 QGFSPKLRHVAARTEGATVFGYQ-VMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTG 172
                  + + A     ++ G + V DP  FGV E ++    + + EKP+ PKSN A+ G
Sbjct: 112 -----NFQELIAAP--VSMLGLKKVDDPRNFGVAELNEENNIVRVVEKPQIPKSNQALVG 164

Query: 173 LY-------FYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTG 225
           +Y        YD        Q K  +  E ++T   Q  +E G +T +   +   W D G
Sbjct: 165 VYKIKETPQLYDCLEQNILHQKKSHD--EFQLTDALQCMIEHG-VTFKTF-KVTNWFDCG 220

Query: 226 THDSLIEASTFV 237
             D+L+E +  +
Sbjct: 221 RKDTLLETNAIL 232


>UniRef50_B9MMF1 Nucleotidyl transferase n=1 Tax=Anaerocellum thermophilum DSM 6725
           RepID=B9MMF1_ANATD
          Length = 712

 Score = 77.8 bits (190), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 56/194 (28%), Positives = 99/194 (51%), Gaps = 11/194 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREI-LIITTPEDK- 58
           MKG+I+AGGSGTRL P+T  + K ++P + KP++ Y + +L   GI EI   +    DK 
Sbjct: 1   MKGVIMAGGSGTRLRPLTVSLPKPMIPFFGKPVMEYAVKLLKAHGIFEIATTLQYHPDKI 60

Query: 59  -GYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
             YF+    DG ++G+ +++  +  P G A +    + FL  + + +VL  +       +
Sbjct: 61  INYFE----DGQKWGVNIQHFVEDRPLGTAGSVKNAKVFL--DDTFVVLSGDGITNADLT 114

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPK--SNWAVTGLYF 175
             +     +    T+   +V  P  +G+V  D+  +     EKP   +  SN A TG+Y 
Sbjct: 115 RAIEFHKQKGSKVTIVLKEVEIPIEYGIVLTDEEGKIQRFFEKPSWSEVFSNLANTGIYI 174

Query: 176 YDSKVVEYAKQVKP 189
            + ++++Y +  KP
Sbjct: 175 IEPEILDYIEDGKP 188


>UniRef50_Q3A0B4 Mannose-1-phosphate guanyltransferase n=10 Tax=Desulfuromonadales
           RepID=Q3A0B4_PELCD
          Length = 842

 Score = 77.4 bits (189), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 69/239 (28%), Positives = 109/239 (45%), Gaps = 16/239 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREI--LIITTPE-D 57
           MK +I+AGG GTR+ P+T  + K ++P+ ++P++ + + +L   GI ++  L+   PE  
Sbjct: 1   MKAVIMAGGFGTRMQPLTINLPKPMVPLVNQPIMSHIIDLLKAHGISDVIMLLFHQPEII 60

Query: 58  KGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
           K YF    GDGSE G+++ Y       G A A      +L+     LV+  ++       
Sbjct: 61  KNYF----GDGSELGVRITYVTPLEDFGTAGAVKAAAPYLD--ERFLVISGDLLTDFDLG 114

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYF 175
             L     +   AT+    V DP +FGVV  D         EKP   +  S+   TG+Y 
Sbjct: 115 AVLSFHEEKQALATITLTSVEDPLQFGVVITDQQGAITKFLEKPGWGEVFSDTINTGIYV 174

Query: 176 YDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
            + +V+E    + P E        I    LE G      L +G+ W D G  D+ +E  
Sbjct: 175 LEPEVLE----MIPEETNRDWSKDIFPRMLEEGRPLYGCLQQGY-WADIGNTDAYLETC 228


>UniRef50_Q8ILP1 Mannose-1-phosphate guanyltransferase, putative n=4 Tax=Plasmodium
           RepID=Q8ILP1_PLAF7
          Length = 408

 Score = 77.4 bits (189), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 66/249 (26%), Positives = 109/249 (43%), Gaps = 17/249 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREIL--IITTPEDK 58
           M  +IL GG GTRL P+T    K L+   +KP+I + +  L   GI+EI+  I   P + 
Sbjct: 1   MNALILVGGYGTRLRPLTLTTPKPLINFCNKPIIEHQILHLAKCGIKEIILAIAYKPTNI 60

Query: 59  GYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSP 118
             F + +    ++ +Q+ ++ +  P G      + E +LN      V   +I        
Sbjct: 61  TNFVKEM--EKKYNVQIIFSVEDEPLGTGGPLKLAENYLNKYDDFFVFNSDIICTFPLIE 118

Query: 119 KLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDS 178
            +          T+   +V DP  FGVV  +D       EEKP  PKS+    G+Y  + 
Sbjct: 119 MMNFHKQNKAPLTILVKEVEDPRAFGVVITEDKM-ITKFEEKPLVPKSSLINAGIYILNK 177

Query: 179 KVVEYAKQVKPSERGEL--EITSINQMYLEAGNLTVELLGRGFAWLDTGTH-DSLIEAST 235
           +++ +  Q   S   E+  ++ S N +Y    N         F W D G   D L   S 
Sbjct: 178 QILNFIPQRNCSLEKEIFPKLASDNMLYFYQLN--------NF-WADIGKPLDFLKGQSL 228

Query: 236 FVQTVEKRQ 244
           +++ +E+R+
Sbjct: 229 YMENLEERK 237


>UniRef50_Q0W734 Nucleotidyltransferase family protein n=2 Tax=Euryarchaeota
           RepID=Q0W734_UNCMA
          Length = 231

 Score = 77.4 bits (189), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 69/248 (27%), Positives = 114/248 (45%), Gaps = 31/248 (12%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK  IL GG G RL PIT  + K ++P+  KP++ Y + +L   G+R+I+ +      G+
Sbjct: 1   MKAFILCGGRGERLKPITDKIPKPMVPVAGKPILEYQVDLLKKHGVRDIVFLV-----GW 55

Query: 61  F----QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGF 116
           +    +   GDGS+FGI+ EY+ +   + L  A  I       + + +V+  +I      
Sbjct: 56  YGEAIEAYFGDGSKFGIRAEYSYEDPNNRLGTAGPIKAAKDKVDGAIIVMNGDIISNTNI 115

Query: 117 SPKLRHVAARTEGATVFGYQVMD-PERFGVVEFDDNFRAISLEEKPKQP-KSNWAVTGLY 174
           S     VA  T+   +    +++ P  FG+++ + +       EKP  P K N    GLY
Sbjct: 116 S---EIVAFHTKKKCLGTINMINMPSPFGIIDLNGD-HITQFREKPVLPFKMN---AGLY 168

Query: 175 FYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLG---RGFAWLDTGTHDSLI 231
             ++ VV+    V     G +E     ++  E      +L G    G  W D GTH  L 
Sbjct: 169 VIEADVVDMMPAV-----GSIETDVFPKIAAEG-----KLCGYDSTGIYWSDVGTHKDLE 218

Query: 232 EASTFVQT 239
           + +  VQ+
Sbjct: 219 KVTKDVQS 226


>UniRef50_Q97EX5 Mannose-1-phosphate guanyltransferase (Pyrophosphorylase domain and
           phosphomannomutase domain) n=1 Tax=Clostridium
           acetobutylicum RepID=Q97EX5_CLOAB
          Length = 815

 Score = 77.0 bits (188), Expect = 8e-13,   Method: Compositional matrix adjust.
 Identities = 60/199 (30%), Positives = 95/199 (47%), Gaps = 11/199 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITT---PED 57
           MK II+AGG G RL P+T  + K ++PI  KP++ Y + +L   GI EI I       E 
Sbjct: 1   MKAIIMAGGQGKRLRPLTCNLPKPMMPIMQKPVLQYIIELLKKHGINEIGITLHYLPDEV 60

Query: 58  KGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
             YF    GDG E G+ + Y  + SP G A +    E+FL  + + +V+  +       +
Sbjct: 61  MDYF----GDGKELGVNIHYFIEQSPLGTAGSVRNAESFL--DETFVVISGDALTDVNLT 114

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYF 175
             L++   +    T+   +V  P  +GV   D   R  +  EKP   +  S+ A TG+Y 
Sbjct: 115 NILQYHKEKNAMVTIVLKKVTIPLEYGVAITDTEGRISNFIEKPGWGEIFSDKANTGIYV 174

Query: 176 YDSKVVEYAKQVKPSERGE 194
            +  + E+  + K  +  E
Sbjct: 175 MEPGIFEFYNKDKKFDFSE 193


>UniRef50_A9B3S0 Nucleotidyl transferase n=6 Tax=Chloroflexi (class)
           RepID=A9B3S0_HERA2
          Length = 835

 Score = 76.6 bits (187), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 67/228 (29%), Positives = 109/228 (47%), Gaps = 22/228 (9%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +++AGG G+RL P+T    K ++P+ D+P++ + + +L   GI +I IIT       
Sbjct: 1   MKAVLMAGGEGSRLRPLTISRPKPMVPLVDRPVMGHIIELLKRHGITDI-IITVQYLANI 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFL--NGEPSCLVLGDNI--FFGQGF 116
            Q   GDGS F + + Y+ +  P G A A       +  + EP  ++ GD +  F     
Sbjct: 60  IQDFYGDGSAFDVDISYSVEEVPLGTAGAVKYASRLIDDDSEPILVISGDALTDFDLTAL 119

Query: 117 SPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLY 174
               +   A+   AT+   +V +P  +GVV  DD  R     EKP   +  S+   TG+Y
Sbjct: 120 IEAHKRSNAK---ATITLTRVPNPLEYGVVITDDTGRIRQFLEKPSWGEVFSDTVNTGIY 176

Query: 175 FYDSKVV---------EYAKQVKPS--ERGELEITSINQMY-LEAGNL 210
             D  V+         +++K + P+   RGEL    I + Y  + GN+
Sbjct: 177 VIDPCVLDDIPLGEPFDFSKDLFPALLRRGELLHGYIAEGYWTDVGNI 224


>UniRef50_B7XJS8 Mannose-1-phosphate guanyltransferase n=1 Tax=Enterocytozoon
           bieneusi H348 RepID=B7XJS8_ENTBH
          Length = 329

 Score = 76.6 bits (187), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 56/242 (23%), Positives = 116/242 (47%), Gaps = 15/242 (6%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +IL GG GTRL+P+T+   K L+P  +KP+I Y + +L+ AGI+ I++           
Sbjct: 6   AVILVGGKGTRLYPLTKTRPKPLIPFLNKPIIEYQIDLLVEAGIQRIILALNYFSDQIKH 65

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
           + L   + + I++ Y+ +  P G A    + E ++NG  + +V+  +I+     +  +  
Sbjct: 66  KALEWKANYNIEIIYSHELEPLGTAGPLKLAEKYINGN-AFIVMNADIYTSINLTSMITE 124

Query: 123 VAARTE-GATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPK--SNWAVTGLYFYDSK 179
              +    A + G +V +P+++G++E   N    +  EKP      +N    G+Y ++  
Sbjct: 125 FKTKKNYDAILLGVEVDNPDKYGLIEI-KNGTVTNFIEKPSYTNGPTNIINGGIYIFNRN 183

Query: 180 VVEYA--------KQVKPS--ERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDS 229
           ++ +         K++ P   +  ++ I   N ++ + G     L G+  A  +T T + 
Sbjct: 184 ILNFIELKYVSIEKEIFPQLVQNQKMTIFHFNGIWCDIGVPNEYLKGQKKALGNTNTSNV 243

Query: 230 LI 231
           ++
Sbjct: 244 IL 245


>UniRef50_C1DV53 Mannose-1-phosphate guanyltransferase n=4 Tax=cellular organisms
           RepID=C1DV53_SULAA
          Length = 830

 Score = 76.6 bits (187), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 61/196 (31%), Positives = 94/196 (47%), Gaps = 27/196 (13%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIIT--TPEDK 58
           MK +I+AGG GTR+ P+T  + K +LP+ +KPM+ + +  +   GI EI+I+    PE  
Sbjct: 1   MKAVIMAGGFGTRIQPLTNSIPKPMLPVLNKPMMEHIIKKVKAVGITEIVILLYFKPE-- 58

Query: 59  GYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGD---------N 109
              Q    DGS+FGI++ Y       G A A      +L+ E   ++ GD          
Sbjct: 59  -VIQNYFKDGSDFGIKINYVLPDDDYGTAGAVKKAAKYLD-ERFIVISGDLVTDFDLKEI 116

Query: 110 IFFGQGFSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSN 167
           I F Q    KL          T+    V DP +FGVV  D + + +   EKP   +  S+
Sbjct: 117 IGFHQAVGSKL----------TITLTSVEDPLQFGVVITDKDGKILRFLEKPGWGEVFSD 166

Query: 168 WAVTGLYFYDSKVVEY 183
              TG+Y  + +++ Y
Sbjct: 167 TINTGIYVIEPEILNY 182


>UniRef50_C0GEN7 Nucleotidyl transferase n=1 Tax=Dethiobacter alkaliphilus AHT 1
           RepID=C0GEN7_9FIRM
          Length = 824

 Score = 76.6 bits (187), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 56/190 (29%), Positives = 94/190 (49%), Gaps = 9/190 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITT--PEDK 58
           MK II+AGG G+RL P+T    K ++PI ++PM+ + +S+L    ++EI +     PE  
Sbjct: 1   MKAIIMAGGQGSRLRPLTCDRPKPMVPIMNRPMMEHIVSLLKSYDLKEIGVTLQYLPEQ- 59

Query: 59  GYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSP 118
              +   GDG EFG+ + Y  + SP G A +     +FL+   + +V+  +         
Sbjct: 60  --IENYFGDGREFGVNMRYFIEDSPLGTAGSVKNSGSFLD--ETFIVISGDALTDFDLQK 115

Query: 119 KLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFY 176
            +    A+   AT+    V  P  +GVV  +D  R     EKP   +  S+   TG+Y  
Sbjct: 116 AIEFHRAKGGVATLVLTSVETPLEYGVVIANDEGRITQFLEKPSWGEVFSDTVNTGIYIL 175

Query: 177 DSKVVEYAKQ 186
           + +V++Y  +
Sbjct: 176 EPEVLQYVPE 185


>UniRef50_C7LY80 Nucleotidyl transferase n=1 Tax=Acidimicrobium ferrooxidans DSM
           10331 RepID=C7LY80_ACIFD
          Length = 346

 Score = 76.3 bits (186), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 68/241 (28%), Positives = 108/241 (44%), Gaps = 9/241 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ IIL GG GTRL P+T    KQ+L +   PM+   +  L   G+ E+++    +   +
Sbjct: 1   MQAIILVGGEGTRLRPLTLHQPKQMLRLLGFPMLERVVERLAAIGVDEVVLSLGYQPDAF 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
             R   D     +++ YA +P P   A A        N   + LV+  ++      +  +
Sbjct: 61  IAR-YPDHRIGTVKVRYAVEPEPLDTAGAIRFAVDKGNVHGTFLVVNGDVLTDLDVAQLV 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDS 178
                R   AT+   +V DP RFGVV  DD  RA+   EKP   Q  S+    G+Y  + 
Sbjct: 120 DFHLDRGALATIGLVEVDDPSRFGVVVTDDRGRAVRFVEKPPRDQAPSHAINAGVYVMEP 179

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
             +E   ++   ER  +E +   Q+  E    T+  L +   W+D GT  S + A+  + 
Sbjct: 180 AAIE---RIAVGERVSVERSLFPQLASEG---TLWGLAQRCYWVDAGTPASYLRAALDIA 233

Query: 239 T 239
           T
Sbjct: 234 T 234


>UniRef50_Q18G10 Glucose-1-phosphate thymidylyltransferase n=5 Tax=Halobacteriaceae
           RepID=Q18G10_HALWD
          Length = 403

 Score = 76.3 bits (186), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 68/239 (28%), Positives = 106/239 (44%), Gaps = 32/239 (13%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPED--- 57
           M+ +ILA G GTR+ P+T   +K +LP+  +P+  +     + AG   ++ +   E    
Sbjct: 1   MQTVILAAGKGTRMRPLTESTAKPMLPVVGEPIAAHTAQAAINAGASRLIFVIGYEAESV 60

Query: 58  KGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
           K YF     D       + YA Q    G A A    +  L  +P  ++ GDN++      
Sbjct: 61  KEYFGESYQD-----TPVAYATQTEQRGTADAVRAAKAELTEDPFVVLNGDNLYDVSSL- 114

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEF--------DDNFRAISLEEKPKQPKSNWA 169
            +  +V+A + G      +V +P  +GV+E         D + R   + EKP  P SN  
Sbjct: 115 -ESLYVSAPSIGTV----RVENPSAYGVLEITEDNESESDMSKRVSGVVEKPANPPSNRI 169

Query: 170 VTGLYFYDSKVVEYAK---QVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTG 225
             G Y +     E A+    V PSER E E+T   Q   E+ ++T   + R   WLD G
Sbjct: 170 NAGAYAFP----EAARGWLDVDPSERDEYELTDTLQQTCESVSVTPVDIDR---WLDVG 221


>UniRef50_B3QV42 Nucleotidyl transferase n=1 Tax=Chloroherpeton thalassium ATCC
           35110 RepID=B3QV42_CHLT3
          Length = 847

 Score = 76.3 bits (186), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 56/186 (30%), Positives = 94/186 (50%), Gaps = 11/186 (5%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREI--LIITTPED-K 58
           K II+AGG GTRL P+T  + K L+P+  +PM+++   +L   G++EI  ++   PE  +
Sbjct: 12  KAIIMAGGFGTRLRPLTMNIPKPLVPMMQRPMMHHIAELLKKYGVKEITSMLYYQPESIR 71

Query: 59  GYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSP 118
            YF    GDG +FG ++ Y    +  G A +      F++G    +V+  ++      S 
Sbjct: 72  EYF----GDGKKFGYKMHYILSDADYGTAGSVRNAYDFVDGR--FVVISGDVLTDFDLSK 125

Query: 119 KLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFY 176
            +     R   AT+    V +P +FGVV  D + R     EKP   +  S+   TG+Y  
Sbjct: 126 AIEFHVKRGALATMVLTHVKNPLQFGVVITDKDGRITRFLEKPTWGEVFSDTINTGIYIL 185

Query: 177 DSKVVE 182
           + +V++
Sbjct: 186 EKEVMD 191


>UniRef50_B3LAG9 Mannose-1-phosphate guanyltransferase, putative n=3 Tax=Plasmodium
           RepID=B3LAG9_PLAKH
          Length = 434

 Score = 76.3 bits (186), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 54/183 (29%), Positives = 84/183 (45%), Gaps = 5/183 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREIL--IITTPEDK 58
           M  +IL GG GTRL P+T    K L+   +KP++ + +  L   GIREI+  I   P D 
Sbjct: 1   MNALILVGGYGTRLRPLTLTTPKPLISFCNKPILEHQIFNLARCGIREIILAIAYKPTDI 60

Query: 59  GYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSP 118
             F   L    ++ +++ Y+ +  P G      + E +L+      V   +I        
Sbjct: 61  TNFVDNL--EKKYNVKIIYSIEEEPLGTGGPIKLAEKYLSKYDDFFVFNSDIICSFPLLE 118

Query: 119 KLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDS 178
            +          T+   +V DP  FGVV  ++N R    EEKP+ PKS+    G+Y  + 
Sbjct: 119 MMSFHKQSNAPLTILVKEVEDPRAFGVVITEEN-RITKFEEKPQVPKSSLINAGIYIMNR 177

Query: 179 KVV 181
           KV+
Sbjct: 178 KVL 180


>UniRef50_Q9ZGB3 NDP-hexose synthetase homolog n=1 Tax=Streptomyces cyanogenus
           RepID=Q9ZGB3_STRCY
          Length = 328

 Score = 76.3 bits (186), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 40/112 (35%), Positives = 63/112 (56%), Gaps = 3/112 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKG- 59
           MK ++L+GG+GTRL P+T  + KQL+P+  +P++ + L  +   G+RE  I+ T  D G 
Sbjct: 1   MKALVLSGGTGTRLRPLTHSLPKQLIPLAGRPVVAHVLDSVRDLGVRETGIVVT--DGGE 58

Query: 60  YFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIF 111
             ++ LGDGS  G+ L Y  Q +P G   A  +   FL  +   +  GD + 
Sbjct: 59  QIEQALGDGSRSGLSLTYFRQDTPRGFGHALSLARDFLGDDDFVVYRGDTLV 110


>UniRef50_Q97EQ2 Nucleoside-diphosphate-sugar pyrophosphorylase n=1 Tax=Clostridium
           acetobutylicum RepID=Q97EQ2_CLOAB
          Length = 234

 Score = 75.9 bits (185), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 54/196 (27%), Positives = 91/196 (46%), Gaps = 6/196 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +IL GG GTRL  + +   K +  + +KP + Y +  L   GI +I I+ T     +
Sbjct: 1   MQALILVGGLGTRLRSVVKDRPKPMALVENKPFLEYLIRKLKSNGISDI-ILATGYMSEF 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +    DG EFG+ + Y+++ +  G A A    E +L  E    VL  + +F   F    
Sbjct: 60  IENYFKDGREFGVNIVYSKETTQLGTAGAIKNAEEYLKEE--FFVLNGDTYFDVDFESAY 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           +         T+   +  D  R+G VE  D+ R +S  EK    KSN+   G+Y    ++
Sbjct: 118 KFHKNNKSYFTMILRETSDASRYGAVECSDDNRVVSFIEKGGISKSNYINGGIYIVKKEI 177

Query: 181 VEYAKQVKPSERGELE 196
               K+++  ++  LE
Sbjct: 178 F---KEIEREKKVSLE 190


>UniRef50_UPI0001AF5131 glucose-1-phosphate thymidylyltransferase n=2 Tax=Pseudomonas
           syringae pv. oryzae str. 1_6 RepID=UPI0001AF5131
          Length = 194

 Score = 75.9 bits (185), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 34/47 (72%), Positives = 41/47 (87%)

Query: 195 LEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVE 241
           LEIT +N+ YLE  +LTVE+LGRGFAWLDTGTH+SL+EAS FV T+E
Sbjct: 148 LEITDVNRAYLEQKSLTVEILGRGFAWLDTGTHESLLEASHFVHTIE 194


>UniRef50_Q23RS7 Nucleotidyl transferase family protein n=3 Tax=Eukaryota
           RepID=Q23RS7_TETTH
          Length = 706

 Score = 75.9 bits (185), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 48/188 (25%), Positives = 92/188 (48%), Gaps = 9/188 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +IL GG GTRL P+T    K ++   ++P++ + +  L+  G+ +I++    + K  
Sbjct: 1   MKALILVGGFGTRLRPLTFSCPKSIVEFANQPLVTHQIKALVDVGVTDIILAIGFQPKAM 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDG------LAQAFIIGETFLNGEPSCLVLGDNIFFGQ 114
            +++     E+ +++  +++  P G      LA+  ++ +   N E    VL  ++    
Sbjct: 61  IEKIKQFEEEYKVRIICSQEVEPLGTGGPLRLAKEHLVKD---NPEGLFFVLNSDVICDF 117

Query: 115 GFSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLY 174
            F   L       +  T+   +V DP ++GVV  D N R     EKPKQ  S+    G+Y
Sbjct: 118 PFKEMLAFHKNHQKEGTILLTKVQDPTKYGVVVSDSNGRIERFIEKPKQFISDRINAGIY 177

Query: 175 FYDSKVVE 182
            +++ V++
Sbjct: 178 LFNTSVID 185


>UniRef50_C7M360 UTP-glucose-1-phosphate uridylyltransferase n=2 Tax=Actinobacteria
           (class) RepID=C7M360_ACIFD
          Length = 296

 Score = 75.9 bits (185), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 67/230 (29%), Positives = 103/230 (44%), Gaps = 36/230 (15%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIIT-----TPE 56
           K +I A G GTR  P T+   K++LP+ D+P I Y +   +  G+  IL++T     + E
Sbjct: 4   KVVIPAAGLGTRFLPATKAQPKEMLPVVDQPAIQYVVEEAVTHGLTNILVVTGRGKRSIE 63

Query: 57  DKGYFQR------LLGDGSEFGI-----------QLEYAEQPSPDGLAQAFIIGETFLNG 99
           D  +F R      LL    +F             Q+ Y  Q  P GL  A  +    +  
Sbjct: 64  D--HFDRAVELELLLARQEKFAELALVEHISHLGQIHYLRQGEPRGLGHAVSVAAQHVGR 121

Query: 100 EPSCLVLGDNIFFGQGFSPKLRHVAARTE--GATVFGYQVMDPERF------GVVEFDDN 151
           +P  ++L D+I      SP L  + A  E  GA+V     + PER       GVV+ D  
Sbjct: 122 DPFVVMLADDIMGPA--SPLLADMLALHERTGASVLSLMEVPPERIRLYGAAGVVDEDGV 179

Query: 152 FRAISLEEKP--KQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITS 199
               S+ EKP   +  SN A+TG Y +   + +   +  P + GE+++T 
Sbjct: 180 DYVRSVVEKPDASEAPSNLAITGRYIFTPAIFDALAETPPGKGGEIQLTD 229


>UniRef50_B0MQS9 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=B0MQS9_9FIRM
          Length = 289

 Score = 75.9 bits (185), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 68/267 (25%), Positives = 118/267 (44%), Gaps = 34/267 (12%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITT-----PE 56
           K +ILA G GTR+ P ++ + K++L I DKP I Y +  ++ +GI EILI+ +      E
Sbjct: 6   KAVILAAGFGTRVLPASKAIPKEMLNIVDKPAIQYIVEEVINSGITEILIVLSRGKQEVE 65

Query: 57  D----------------KGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGE 100
           D                K  F +++ D +E G  + Y  Q   +G   A +  + F+  +
Sbjct: 66  DHFDRKPDLEAQLLAGGKTEFYKVVCDIAEMGKNITYVRQQMQNGTGGAVMYAKQFVGND 125

Query: 101 PSCLVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQ------VMDPERFGVVEFDDNFRA 154
           P  ++ GD++  G          A    G  V   +      V+      V   +DN  +
Sbjct: 126 PFVVIYGDDVIIGDDPCTAQCCRAYEKYGKAVVSMKEVPFELVLKYCTLDVKPLEDNLYS 185

Query: 155 IS-LEEKPKQPK--SNWAVTGLYFYDSKVVEYAKQVKPSERGELEIT-SINQMYLEAGNL 210
           IS + EKPK  +  SN+A+ G     +K+ +    +     GE ++T ++ Q+    G +
Sbjct: 186 ISDMIEKPKPEEVISNFAILGRCVLPAKIFDILATLPTGAGGEYQLTDAMKQLAKSEGMV 245

Query: 211 TVELLGRGFAWLDTGTHDSLIEASTFV 237
            V+  G  +   D G    +++A   V
Sbjct: 246 GVDFTGTRY---DMGNKLGIMKACVEV 269


>UniRef50_Q54800 UTP--glucose-1-phosphate uridylyltransferase n=15 Tax=Bacteria
           RepID=CAP3C_STRPN
          Length = 306

 Score = 75.5 bits (184), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 60/251 (23%), Positives = 111/251 (44%), Gaps = 37/251 (14%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIIT-----TPE 56
           K +I A G GTR  P T+ ++K++LPI D+P I++ +   + +GI +IL++T     + E
Sbjct: 6   KAVIPAAGLGTRFLPATKALAKEMLPIVDRPTIHFVIEEALRSGIEDILVVTGKSKRSIE 65

Query: 57  D--------------KGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPS 102
           D              +G  + L        I++ +  Q SP GL  A +  ++F+  +P 
Sbjct: 66  DYFDSTFELEYSLRKQGKMELLKSVNESTDIKVHFVRQSSPRGLGDAVLQAKSFVGDDPF 125

Query: 103 CLVLGDNIF--FGQGFSPKLRHV-----AARTEGATVFGYQVMDPERFGVV----EFDDN 151
            ++LGD++         P  R +     A +     V   +  D   +GV+    E  + 
Sbjct: 126 VVMLGDDLMDITDSTAVPLTRQLMDDYNATQASTIAVMPVRYEDVSSYGVISPRLESSNG 185

Query: 152 FRAISL---EEKPKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAG 208
             ++     + KP++  SN A+ G Y    ++    +  KP    E+++T      ++  
Sbjct: 186 LYSVDAFVEKPKPEEAPSNLAIIGRYLLTPEIFSILETQKPGAGNEIQLTDA----IDTL 241

Query: 209 NLTVELLGRGF 219
           N T  +  R F
Sbjct: 242 NKTQSVFAREF 252


>UniRef50_B4VDY2 dTDP-glucose synthase n=1 Tax=Streptomyces sp. Mg1
           RepID=B4VDY2_9ACTO
          Length = 190

 Score = 75.5 bits (184), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 59/205 (28%), Positives = 91/205 (44%), Gaps = 46/205 (22%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++L+GGSGTRLHP+     +Q  P  DKP++++ L  +  AGI ++ I+   +    
Sbjct: 1   MKALVLSGGSGTRLHPLPVNSPEQPHPAADKPVLFHALEDIADAGITDVGIVLG-DTADE 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFF---GQGFS 117
            +  +GDG+ FG+ + Y  +  P GLA A      +         LGD+ F    G GF 
Sbjct: 60  VRAAVGDGARFGVSVTYLPRRRPAGLAHAVRTARDW---------LGDDDFVTHPGDGFV 110

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAIS--LEEKPKQPKSNWAVTGLYF 175
           P                         G+ E  + FR+     +E P +        G+YF
Sbjct: 111 PG------------------------GIGEQLEEFRSRRPVAQEVPGR-------AGVYF 139

Query: 176 YDSKVVEYAKQVKPSERGELEITSI 200
           +   V    + V+PS  GELEI  +
Sbjct: 140 FTDAVHRAVEAVQPSGHGELEIAEV 164


>UniRef50_Q0W805 Putative glucose-1-phosphate thymidylyltransferase n=2
           Tax=Euryarchaeota RepID=Q0W805_UNCMA
          Length = 332

 Score = 75.5 bits (184), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 68/256 (26%), Positives = 117/256 (45%), Gaps = 17/256 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +I A G+G RL+P T    K ++ +  KP+I + L   +     E++I+      GY
Sbjct: 1   MKVVIPAAGAGKRLYPHTYTKPKPMVYVAGKPIIGHILDKAVDLQPDELIIVV-----GY 55

Query: 61  FQRLLGDGSE---FGI--QLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQG 115
            +  L D  +    GI  ++ Y  Q    GL  +  +    ++  P  + LGD IF G G
Sbjct: 56  MKEKLIDYVDEHYCGIFKKITYVHQDQQLGLGHSIYVAREAIDDAPIMIALGDMIFKG-G 114

Query: 116 FSPKLRHVAARTEGATVFGYQVMD-PERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLY 174
           +S   R  A   + +   G + +D P  +G+V  + +     + EKPK+  S   + G+Y
Sbjct: 115 YSDFARLHACNGKCSGSIGVKEIDNPSHYGIVFLNGDGTIKKMVEKPKKSSSRLGIAGVY 174

Query: 175 FYDSK---VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLI 231
           F D     +    K V+    GE+++T   Q  +EAG+          +W D G  +SL+
Sbjct: 175 FIDDTPGLIRALEKVVENRGEGEVQLTDALQKAIEAGSDYKPF--EVSSWYDCGRPESLL 232

Query: 232 EASTFVQTVEKRQGFK 247
           E +  +   + +  +K
Sbjct: 233 EVNRLLLAEKSKMSWK 248


>UniRef50_Q6L165 Mannose-1-phosphate guanyltransferase n=3 Tax=Thermoplasmatales
           RepID=Q6L165_PICTO
          Length = 361

 Score = 75.5 bits (184), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 67/253 (26%), Positives = 117/253 (46%), Gaps = 23/253 (9%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +K +++AGG GTRL PIT  + K L+PI  KP + Y +     AGI++ ++ T     GY
Sbjct: 3   LKAVVMAGGKGTRLRPITYSIPKPLVPIAGKPCVSYLMDSFYDAGIKDAIVTT-----GY 57

Query: 61  -FQRLLG---DGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGF 116
            F+ L+    +  +    + ++ +  P G A +  +   F+  + + +V   +I +    
Sbjct: 58  KFESLINGIIEAKKPDQNVLFSVEREPAGTAGSVKLISNFI--DDTIVVGSGDILYDFDI 115

Query: 117 SPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLY 174
              +     +    T+   +V DP +FG+V+  D+     L EKP   +  SN    G+Y
Sbjct: 116 KSIIDFHKKKNASVTIVLTRVDDPSQFGIVDLKDDVITRFL-EKPAAGEAFSNIVNAGIY 174

Query: 175 FYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
             + +V++Y  ++      EL         +  G      LG G  WLDTG  + LI+ +
Sbjct: 175 VIEPEVLKYIDKIPFDFAKELF-----PRLMRHGTPIYGYLGNG-TWLDTGRPNDLIKGN 228

Query: 235 TFVQTVEKRQGFK 247
              Q +  + GFK
Sbjct: 229 ---QIMVNKYGFK 238


>UniRef50_C4RN52 UTP-glucose-1-phosphate uridylyltransferase galU n=4
           Tax=Actinomycetales RepID=C4RN52_9ACTO
          Length = 333

 Score = 74.7 bits (182), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 75/289 (25%), Positives = 126/289 (43%), Gaps = 49/289 (16%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIIT------- 53
           +K +I A G  TR  P T+ V K+LLP+ D+P++ + +     AGI ++L+IT       
Sbjct: 20  VKAVIPAAGLATRFLPATKAVPKELLPVVDRPVLQFIVEEATQAGIGDVLLITGRGKTSM 79

Query: 54  ------TP------EDKGYFQRLLG-DGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGE 100
                  P      E KG  +RL    G     ++    QP   GL  A    E+ +  +
Sbjct: 80  VDHFDRRPDLEARLESKGDTERLAAVRGPSELAEIYTCRQPEQLGLGHAVGYAESHVGDQ 139

Query: 101 PSCLVLGDN-IFFGQGFSPKLRHVAARTEGATVFGYQVMDP---ERFGVVEFD------- 149
           P  ++LGD  +   +   P +  + ART G  V  +  +DP   +R+G+   +       
Sbjct: 140 PFAVLLGDEFVKPSEPLLPAMLELQART-GGIVLAFFEVDPAETKRYGIASVEAAEPELT 198

Query: 150 ---DNFRAISLEEKPK--QPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMY 204
              +  +   + EKPK     SN AV G Y    ++ +  ++ +P   GE+++T   ++ 
Sbjct: 199 DIGEVVKVTGMVEKPKPEDAPSNLAVLGRYVLPGRIFDAIRRTEPGSGGEIQLTDAMELL 258

Query: 205 LEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEKRQGFKIACLEE 253
              G     ++ RG  + DTG          ++QTV      +IAC  E
Sbjct: 259 RTEGVPVHAIVYRGTRY-DTGM------PLGYLQTV-----VQIACERE 295


>UniRef50_B6BPC5 UTP--glucose-1-phosphate uridylyltransferase n=4 Tax=SAR11 cluster
           RepID=B6BPC5_9RICK
          Length = 271

 Score = 74.7 bits (182), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 66/264 (25%), Positives = 119/264 (45%), Gaps = 35/264 (13%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDK---- 58
            II   G GTRL P+T   +K+LLPI  KP + Y ++  + AGI++I+ I +   K    
Sbjct: 5   AIIPLAGLGTRLLPLTSVFAKELLPINGKPGLEYIINECIDAGIKQIIFIISKRKKMIKK 64

Query: 59  -----GYFQRLLGDGSEFGIQLEYAE------------QPSPDGLAQAFIIGETFLNGEP 101
                 +++ L+   ++  +  EY +            Q  P G   A +  + ++  + 
Sbjct: 65  YFYNDKFYKELIKKKNDPRVIKEYKKILKYRKMIKFVYQNKPKGTGDAVLKTKKYIKDKY 124

Query: 102 SCLVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQVMDP--ERFGVVEFDD--NFRAISL 157
             ++L D++   +  S  +     + + + +    V      R+G+ + +   N    S+
Sbjct: 125 FLMLLPDDLIIKKNCSKSMIQTHNKFKSSVMASMSVNKKTVSRWGIYKINKKLNITDYSI 184

Query: 158 E---EKP--KQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTV 212
           +   EKP  K+  SN AV G Y    K+    +++KPS+ GE+ IT   Q+ +   N   
Sbjct: 185 KGVIEKPKIKEAPSNKAVIGRYILPKKIFTKLRKLKPSKGGEIHITDAIQLLI---NDKE 241

Query: 213 ELLGRGFA--WLDTGTHDSLIEAS 234
           + +   F   +LD GT D  I +S
Sbjct: 242 KFIAHNFTGKYLDCGTMDGYINSS 265


>UniRef50_C6CVH3 Nucleotidyl transferase n=3 Tax=Bacillales RepID=C6CVH3_PAESJ
          Length = 411

 Score = 74.7 bits (182), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 72/257 (28%), Positives = 118/257 (45%), Gaps = 33/257 (12%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDK-PMIYYPLSVLMLAGIREILIITTPEDKGYF 61
            ++LAGG G RL P+T  ++K ++P  ++  MI +PLS  M +GIR I ++T        
Sbjct: 8   AMLLAGGEGKRLAPLTTALAKPVVPFGEQYRMIDFPLSNCMNSGIRRIGVLTQ-FCADTV 66

Query: 62  QRLLGDGSEF----------GIQLEYAEQPSPDGL----AQAFIIGETFL---NGEPSCL 104
            R +G G  +           I L  A   SP+G     A A     +++   N E   +
Sbjct: 67  HRHIGGGEAWLNAVQPKHLGEIALLPASVASPNGCYTGTADAIYRNLSYIEQHNPEHVLI 126

Query: 105 VLGDNIFFGQGFSPKLRHVAARTEGATVFGYQV--MDPERFGVVEFDDNFRAISLEEKPK 162
           + GD+I+    + P L         AT+   +V   +  RFG++  ++++  +  EEKP 
Sbjct: 127 LSGDHIY-QMDYRPMLEAHIKSGAAATIAVKRVPWHEASRFGILNTNEDYSVVEFEEKPS 185

Query: 163 QPKSNWAVTGLYFYDSKVV------EYAKQVKPSERGELEITSINQMYLEAGNLTVELLG 216
           +P+SN A  G+Y + + ++      +    V   + G+     I  M L+ G        
Sbjct: 186 RPRSNLASMGIYMFRTDMLREVLLKDAGNPVSSHDFGK----DIIPMLLQDGASLTAYPY 241

Query: 217 RGFAWLDTGTHDSLIEA 233
            G+ W D GT DSL EA
Sbjct: 242 EGY-WRDVGTVDSLWEA 257


>UniRef50_A4J6Z1 Nucleotidyl transferase n=3 Tax=Peptococcaceae RepID=A4J6Z1_DESRM
          Length = 828

 Score = 74.3 bits (181), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 55/188 (29%), Positives = 94/188 (50%), Gaps = 11/188 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITT--PED- 57
           MK II+AGG GTRL P+T G+ K ++P+ ++PM+ + L +L   G+ +I +     PE  
Sbjct: 7   MKAIIMAGGEGTRLRPLTCGLPKPMMPVCNRPMMEHILHLLKKHGVHDIGVTLQYLPEAI 66

Query: 58  KGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
           +GYF    G+G++F + + Y  +  P G A +    + FL  + + +V+  +       S
Sbjct: 67  RGYF----GNGADFNVHMRYYVEEVPLGTAGSVKNAQKFL--DETFIVISGDALTDLDLS 120

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYF 175
             L     +   AT+    V  P  +GVV  + +       EKP   +  S+   TG+Y 
Sbjct: 121 QALEFHRKKGAIATLVLTPVDIPLEYGVVITNGDGHITQFLEKPGWGEVFSDTVNTGIYI 180

Query: 176 YDSKVVEY 183
            + +V+ Y
Sbjct: 181 LEPEVLNY 188


>UniRef50_Q8DLP2 Mannose-1-phosphate guanyltransferase n=9 Tax=Cyanobacteria
           RepID=Q8DLP2_THEEB
          Length = 843

 Score = 74.3 bits (181), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 53/186 (28%), Positives = 95/186 (51%), Gaps = 6/186 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +++AGGSGTRL P+T  + K ++P+ ++P+  + L++L    + ++ ++T       
Sbjct: 1   MRVVVMAGGSGTRLRPLTCDLPKPMVPVVNRPIAEHILNLLRRHNLDDV-VMTLHYLPDV 59

Query: 61  FQRLLGDGSEFGIQLEY-AEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK 119
            +   GDG+EFG+ L Y  E+  P G A + +     L  +P  +V GD+I      +  
Sbjct: 60  VRDYFGDGNEFGVHLSYVVEEEQPLGTAGS-VKNIVNLLTDPFLVVSGDSI-TDVDLTDA 117

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPK--SNWAVTGLYFYD 177
           LR         T+   +V  P+ FG+V  D + R     EKP   +  ++   TG+Y  +
Sbjct: 118 LRFHQQHGAPVTLILARVPQPKEFGIVFTDSDGRVRRFLEKPSAAEVFTDTVNTGIYILN 177

Query: 178 SKVVEY 183
             V++Y
Sbjct: 178 PTVMDY 183


>UniRef50_B1XM99 Sugar-phosphate nucleotidyl transferase n=59 Tax=cellular organisms
           RepID=B1XM99_SYNP2
          Length = 409

 Score = 74.3 bits (181), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 70/242 (28%), Positives = 111/242 (45%), Gaps = 26/242 (10%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITT---PED 57
           MK +ILA G GTR+ PIT  + K L+PI  KP++ + L +L   G  +I++  +    E 
Sbjct: 1   MKAMILAAGKGTRVRPITYTIPKPLIPILQKPVMEFLLDLLAQHGFDQIMVNVSHLAHEI 60

Query: 58  KGYFQRLLGDGSEFGIQLEYAEQPS-PDGLAQAFIIGET-----FLNGEP----SCLVLG 107
           +GYF+    DG  +G+ L Y+ + S  DG  Q   +G         +  P    + +VL 
Sbjct: 61  EGYFK----DGQRYGVHLAYSFEGSIQDGELQGAALGSAGGLRKIQDFHPFFDDTFVVLC 116

Query: 108 DNIFFGQGFSPKLRHVAARTEGATVFGYQVMDP--ERFGVVEFDDNFRAISLEEKPK--Q 163
            +       +  +R    +   ATV    V       +GVV  DD  R +S +EKP   +
Sbjct: 117 GDALIDLDLTAAVRWHREKGAIATVITKSVPKEAVSSYGVVVTDDEDRILSFQEKPSVTE 176

Query: 164 PKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLD 223
             S    TG+Y ++ +V+++   + P+   E +I       L A N     L   F W+D
Sbjct: 177 ALSTKINTGIYIFEPEVIDF---IPPN--CEFDIGGQLFPKLVAANAPFYALDMDFEWVD 231

Query: 224 TG 225
            G
Sbjct: 232 IG 233


>UniRef50_D2AV47 Phosphoglucomutase/phosphomannomutase family protein n=27
           Tax=Bacteria RepID=D2AV47_STRRD
          Length = 828

 Score = 73.9 bits (180), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 67/236 (28%), Positives = 107/236 (45%), Gaps = 13/236 (5%)

Query: 6   LAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQRLL 65
           +AGG GTRL P+T    K LLP+ ++P++ + L +L   G+ E  ++T        +   
Sbjct: 1   MAGGEGTRLRPMTANQPKPLLPVINRPIMEHVLRLLRRHGLTET-VVTVQFLAALVRNYF 59

Query: 66  GDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHVAA 125
           GDG E G+ L YA + +P G A +       L  +   ++ GD +      +  +R    
Sbjct: 60  GDGDELGMSLYYATEDTPLGTAGSVKNAADKLRDDRFLVISGDAL-TDIDLTDMIRF--H 116

Query: 126 RTEGA--TVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDSKVV 181
           R  GA  T+   +V +P  FG+V  DD+ R     EKP   Q  S+   TG+Y  + +V+
Sbjct: 117 RENGALVTIGLKRVPNPLEFGIVIVDDHGRVERFLEKPTWGQVFSDTVNTGIYVMEPEVL 176

Query: 182 EYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
           +      P +        +    L  G      +  G+ W D GTH+S + A   V
Sbjct: 177 DEIAAGVPVDWS----ADVFPRLLARGAPLYGYVAEGY-WEDVGTHESYLRAQADV 227


>UniRef50_C9RJ30 Nucleotidyl transferase n=1 Tax=Fibrobacter succinogenes subsp.
           succinogenes S85 RepID=C9RJ30_FIBSS
          Length = 306

 Score = 73.9 bits (180), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 64/251 (25%), Positives = 110/251 (43%), Gaps = 32/251 (12%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++   G+G RL P T  + K LLP+  K ++ + +   +     E + IT     GY
Sbjct: 1   MKIVLPVAGNGIRLRPYTENLPKCLLPVAGKTILDWIVDDALFLNPSETIFIT-----GY 55

Query: 61  FQRLLGD----GSEFGIQLEYAEQPSPDGLAQAFIIGETFLNG-EPSCLVLGDNIFFGQG 115
               + D      E+G  +    Q +P GL +A  +   ++N  EP  ++LGD +F    
Sbjct: 56  KASAVDDFLKQKPEWG-AVRTVVQSNPQGLGEAISLALPYVNDDEPLLIILGDTLFEAD- 113

Query: 116 FSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYF 175
                  +        ++ ++V DP+RFGV   D N     L EKP++  S+ A+ G+Y+
Sbjct: 114 -----LSILKNASENILYTFKVADPKRFGVAVTDKNGHIERLVEKPQEFVSDEAIVGIYY 168

Query: 176 YDS-----KVVEYAKQVKPSERGELEITSINQMYLEAG----NLTVELLGRGFAWLDTGT 226
                   + + Y  Q     +GE ++T   +  ++ G       VE       WLD G 
Sbjct: 169 IKDVKALKEALNYLMQNDIRTKGEFQLTDALERMIQGGCKFRTAPVE------KWLDCGL 222

Query: 227 HDSLIEASTFV 237
            ++L+  +  V
Sbjct: 223 VETLLATNAHV 233


>UniRef50_B5GDG2 Nucleotide phosphorylase n=1 Tax=Streptomyces sp. SPB74
           RepID=B5GDG2_9ACTO
          Length = 360

 Score = 73.9 bits (180), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 62/239 (25%), Positives = 110/239 (46%), Gaps = 13/239 (5%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           + I+L GG GTRL P+T    K ++P    P + + L+    AG+  I++ T+   +  F
Sbjct: 24  EAILLVGGKGTRLRPLTVNTPKPMVPAAGVPFLAHQLARARAAGVEHIVLATSYLAE-VF 82

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEP--SCLVLGDNIFFGQGFSPK 119
           +   GDGS FG++++Y  +  P G   A     + L   P    LV   +I  G   +  
Sbjct: 83  EPYFGDGSAFGLRVDYVTEREPLGTGGALRNVASHLESGPEDPVLVFNGDILTGLDINAL 142

Query: 120 L-RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPK---SNWAVTGLYF 175
           +  HV A  +  ++   +V DP  FG+V  D + R ++  EKP+ P+   ++    G Y 
Sbjct: 143 VDTHVTAGAD-VSLHLSRVDDPRAFGLVPTDASGRVLAFLEKPQTPEEIVTDQINAGAYV 201

Query: 176 YDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
           +  +V++     +P     +E  +   +     +L  + +     WLD GT  + +  S
Sbjct: 202 FRRRVIDAIPGGRPV---SVERETFPGLLASGAHL--QGMVDSTYWLDLGTPQAFVRGS 255


>UniRef50_A3DL04 Nucleotidyl transferase n=1 Tax=Staphylothermus marinus F1
           RepID=A3DL04_STAMF
          Length = 837

 Score = 73.9 bits (180), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 63/258 (24%), Positives = 110/258 (42%), Gaps = 34/258 (13%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +K II+AGG GTRL P+T    K L+P+ +KP++ + + +L   G ++I  +T       
Sbjct: 2   VKAIIMAGGEGTRLRPLTVNRPKPLVPLVNKPLMEHVVHLLKSKGFKDIG-VTLHYLPNT 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
             R  GDGSEFG+++ Y+ +  P G A          + + + +V+  ++F        L
Sbjct: 61  IMRYFGDGSEFGVRIYYSIEEKPLGTAGGVRFLADKYDWDETIIVISGDVFTNIDLEKML 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPK--SNWAVTGLYFYDS 178
            +   +    T+   +  DP ++G+   D+  R     EKP   +  S+    G+Y  + 
Sbjct: 121 EYHRRKGSIFTMAVRKTDDPTKYGIALLDEEGRVRRFLEKPSWSEVFSDLINMGIYILEP 180

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELL----------GRGFAWLDTG--- 225
           +               LE+   N+ Y  A NL  +LL             + W D G   
Sbjct: 181 EA--------------LEMIPSNEEYDFAKNLIPKLLRFDKPVYGWRADNYYWSDIGSIN 226

Query: 226 ----THDSLIEASTFVQT 239
               TH+ ++     + T
Sbjct: 227 QYKETHNDILSGKVGIDT 244


>UniRef50_Q2RH64 Nucleotidyl transferase n=1 Tax=Moorella thermoacetica ATCC 39073
           RepID=Q2RH64_MOOTA
          Length = 821

 Score = 73.9 bits (180), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 64/230 (27%), Positives = 106/230 (46%), Gaps = 27/230 (11%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK II+AGG G+RL P+T    K L+P+ ++P++ Y + +L   GI+E+  +T       
Sbjct: 1   MKAIIMAGGEGSRLRPLTCKRPKPLVPVANRPVMEYCVDLLRELGIKEV-GVTLQYLPQL 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLA-----QAFIIGETFLNGEPSCLVLGDNIFFGQG 115
            +   GDGS+FG+ L Y  +  P G A      A I+ ETF       +V+  +      
Sbjct: 60  IEEYFGDGSDFGLHLHYFVEDKPLGTAGSVKNAAAILDETF-------VVVSGDALTDFD 112

Query: 116 FSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPK--SNWAVTGL 173
             P +         AT+    V +P  +GVV  + +    S  EKP   +  S+   TG+
Sbjct: 113 LRPAIARHKESGALATLVLTAVDNPLEYGVVITNPDGSIRSFLEKPSWGEVFSDRVNTGI 172

Query: 174 YFYDSKVVEYAKQVKP------------SERGELEITSINQMYLEAGNLT 211
           Y  + +V+E   + +P             E+  L   +++  + + GNLT
Sbjct: 173 YILEPEVLELIPEGRPFDFSKDLFPRLLKEKRPLYGVTLSGYWCDIGNLT 222


>UniRef50_A9FF13 Putative sugar-phosphate nucleotide transferase n=1 Tax=Sorangium
           cellulosum 'So ce 56' RepID=A9FF13_SORC5
          Length = 236

 Score = 73.9 bits (180), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 60/233 (25%), Positives = 99/233 (42%), Gaps = 11/233 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++LAGG G+RL P T  + K L+PI D  ++   L  L  AG+ ++ ++        
Sbjct: 1   MKAVVLAGGKGSRLRPYTALIPKPLMPIGDHTIVEILLRQLARAGVTDV-VMCVGHQAAL 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            + ++G+GS +G+++ Y  + +P G      + E  L      LV+  +I     F+   
Sbjct: 60  IEAVVGEGSRYGLRIAYQREDTPLGTVGPLRVIERDL--PERFLVMNGDILSDLDFTALH 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           R   +     TV   +       GV++   + R +S  EKP    + W   G+Y     V
Sbjct: 118 RTGESAGSPLTVAVCERASKIDLGVLDLGADGRVVSFREKPTY--TFWVSMGIYAMSRDV 175

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEA 233
           + +  + +P          +    L AG        RG  WLD G  D   EA
Sbjct: 176 LPFIPEGRP-----FGFDDLMHALLGAGEPVATFPFRGH-WLDIGRSDDFAEA 222


>UniRef50_UPI000186E54F Mannose-1-phosphate guanyltransferase, putative n=1 Tax=Pediculus
           humanus corporis RepID=UPI000186E54F
          Length = 348

 Score = 73.6 bits (179), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 51/184 (27%), Positives = 87/184 (47%), Gaps = 3/184 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +IL GG GTRL P+T    K L+   +KPM+ + +  L+ AG+ EI++  +   +  
Sbjct: 12  MKALILVGGYGTRLRPLTLSRPKPLVEFANKPMLIHQIEALVDAGVTEIVLAVSYRAQQM 71

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFL--NGEPSCLVLGDNIFFGQGFSP 118
            + L    +  G+ L ++E+  P G A    +    L  + EP   VL  +I     F  
Sbjct: 72  EKELTERAANLGVTLIFSEESEPLGTAGPLALAREILGTSSEP-FFVLNSDIICDFPFKE 130

Query: 119 KLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDS 178
                    +  T+   +V +P ++GVV + +  +  S  EKP++  SN    G+Y    
Sbjct: 131 MYEFHKNHGKEGTIVVTKVDEPSKYGVVVYGEEGKVESFIEKPQEFVSNKINAGMYILSP 190

Query: 179 KVVE 182
            V++
Sbjct: 191 SVLK 194


>UniRef50_Q2J5Q2 UDP-glucose pyrophosphorylase n=51 Tax=Bacteria RepID=Q2J5Q2_FRASC
          Length = 348

 Score = 73.6 bits (179), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 65/237 (27%), Positives = 100/237 (42%), Gaps = 40/237 (16%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKG-- 59
           K +I A G GTR  P T+ V K++LP+ D+P I Y +     AG+R++L++T+   K   
Sbjct: 29  KAVIPAAGLGTRFLPATKAVPKEMLPVVDRPAIEYVVEEASRAGLRDVLLVTSRTKKAIE 88

Query: 60  -YFQR-------LLGDGSEF-----GIQLEYAE-----QPSPDGLAQAFIIGETFLNGEP 101
            +F R       L   G +       +  E AE     Q SP GL  A +     +  EP
Sbjct: 89  DHFDREADIEAALERKGDDLRLRRVRVSAELAEVHSVRQQSPRGLGHAVLCAAAHVGNEP 148

Query: 102 SCLVLGDNIFFGQGFSPKLRHVAARTEGATVFG-----------YQVMDPERFGVV---- 146
             ++LGD++   +    +      R  G +V             Y V   E  G      
Sbjct: 149 FAVLLGDDLIDERDLLLEEMLAVQRRFGGSVIALMEVPEDQVSLYGVATVESVGTSAGTG 208

Query: 147 EFDDNF---RAISLEEKP--KQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEIT 198
             DD +   R   L EKP   Q  SN A+ G Y     + +  ++ +P   GE+++T
Sbjct: 209 SADDRYGIVRIRDLVEKPPVAQAPSNLAIIGRYILSPTIFDVLRRTEPGRGGEIQLT 265


>UniRef50_C8WLR8 Nucleotidyl transferase n=3 Tax=Coriobacteriaceae
           RepID=C8WLR8_EGGLE
          Length = 272

 Score = 73.6 bits (179), Expect = 7e-12,   Method: Compositional matrix adjust.
 Identities = 72/267 (26%), Positives = 114/267 (42%), Gaps = 33/267 (12%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +I A G GTR  P T+   K++L + D+P I Y +   + +   E++II + E K  
Sbjct: 3   MKALIPAAGLGTRFLPATKAQPKEMLLVVDRPAIQYVVEEGLASDADEVVIINSREKKAI 62

Query: 61  FQRL-----------------LGDGSEF--GIQLEYAEQPSPDGLAQAFIIGETFLNGEP 101
            +                     D  E      + Y  Q    GL  A          EP
Sbjct: 63  EEHFSPNPELVELLRARGKDAYADAVERVGNYNVSYVYQDEALGLGHAVRCAHEKTGDEP 122

Query: 102 SCLVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQ-VMDPE--RFGVVE----FDDNFRA 154
             ++LGD +       P+++ V+    GA+V     V D +  RFGV+      DD ++ 
Sbjct: 123 FYVLLGDVLVPDNKMLPRMQEVSDAHGGASVIAVMPVPDDQVSRFGVIAGAAVADDVWKI 182

Query: 155 ISLEEKP--KQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTV 212
            +L EKP  +   SN AV G Y   ++V+E    V+P   GE+++T      L    +  
Sbjct: 183 DALVEKPALEDAPSNLAVFGRYLLSARVMELLADVEPGVGGEIQLTDALDAVLREEEMYA 242

Query: 213 ELL--GRGFAWLDTGTHDSLIEASTFV 237
            ++    GF   DTGT +S +E +  +
Sbjct: 243 LIIDPADGF---DTGTVESWLETNNVL 266


>UniRef50_UPI00016B22C9 glucose-1-phosphate thymidylyltransferase n=2 Tax=candidate
           division TM7 RepID=UPI00016B22C9
          Length = 85

 Score = 73.6 bits (179), Expect = 8e-12,   Method: Composition-based stats.
 Identities = 35/78 (44%), Positives = 50/78 (64%)

Query: 208 GNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEKRQGFKIACLEEIAWRNGWLDDEGVK 267
           G L V+ L  G  WLDTGT DSL +A+ FV+ ++KR G  I   E+IA++N W+  E + 
Sbjct: 3   GKLQVQTLDNGDVWLDTGTIDSLTDAADFVRVIQKRTGRIIGSPEKIAFKNDWISREQLN 62

Query: 268 RAASSLAKTGYGQYLLEL 285
             A  L K+GYG+YL+ +
Sbjct: 63  TLAEPLKKSGYGKYLVRV 80


>UniRef50_A4YHR3 UDP-glucose pyrophosphorylase n=9 Tax=Sulfolobaceae
           RepID=A4YHR3_METS5
          Length = 255

 Score = 73.2 bits (178), Expect = 9e-12,   Method: Compositional matrix adjust.
 Identities = 61/235 (25%), Positives = 105/235 (44%), Gaps = 40/235 (17%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPI----YDKPMIYYPLSVLMLAGIREILII---- 52
           M+ +I A G GTR+ P ++ + K++ P+      KP+I      L  AG+R+ +I+    
Sbjct: 1   MQAVITAAGLGTRMLPASKEIPKEMFPVPFRGSFKPIIQVIFEQLYDAGVRDFVIVVGRG 60

Query: 53  --------TTPEDKGYFQRLLG------DGSEFGIQLE-----YAEQPSPDGLAQAFIIG 93
                   T  +D  Y+   +G      D + F  ++E     +  Q SP+G   A +  
Sbjct: 61  KRVIEDHFTPDQDFVYYLEKMGKSRQAKDLNAFYEKIEKSNIAFVNQASPEGFGDAVLRA 120

Query: 94  ETFLNGEPSCLVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFR 153
           + F+  +          F        L  +  R E  +    QV DP+ +GVV  D    
Sbjct: 121 KPFIKSD----------FLVSAADTILEEIP-RMEVNSFLVTQVDDPKPYGVVLLDGEL- 168

Query: 154 AISLEEKPKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAG 208
            + +EEKP++PKSNW +   Y +D  + E  ++ K S + EL++T   +  +  G
Sbjct: 169 VVDVEEKPREPKSNWVIAPYYHFDYMIFEALEKTKRSGK-ELQLTDAIKYLMNNG 222


>UniRef50_A4X2X2 UDP-glucose pyrophosphorylase n=3 Tax=Actinomycetales
           RepID=A4X2X2_SALTO
          Length = 318

 Score = 73.2 bits (178), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 68/259 (26%), Positives = 115/259 (44%), Gaps = 36/259 (13%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTP----- 55
           +K +I A G  TR  P T+ V K+LLP+ D+P++ Y +     AGI ++L+IT       
Sbjct: 21  VKAVIPAAGLATRFLPATKAVPKELLPVVDRPVLQYIVEEATEAGITDVLLITGRGKTSM 80

Query: 56  ----EDKGYFQRLLGDGSEFGIQLEYAE---------QPSPDGLAQAFIIGETFLNGEPS 102
               + +   +  L    E    ++  E         QP   GL  A    E+ +  +P 
Sbjct: 81  VDHFDRRPDLEERLAKKPELLAAVKRTEDLAAIYTCRQPEQLGLGHAVGYAESHIGDQPF 140

Query: 103 CLVLGDN-IFFGQGFSPKLRHVAARTEGATVFGYQVMDPE---RFGVV-------EFDD- 150
            ++LGD  +   +   P +  + ART G  V  +  +DP+   R+G+        EF D 
Sbjct: 141 AVLLGDEFVKPTEPLLPAMLELQART-GGIVLAFFEVDPDETTRYGIASVAPAEAEFADI 199

Query: 151 --NFRAISLEEKPK--QPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLE 206
               R   + EKP+  +  SN AV G Y    ++ +   + +P   GE+++T   ++   
Sbjct: 200 AEVVRVTGMVEKPEPEEAPSNLAVLGRYVLPGRIFDAIHRTEPGSGGEIQLTDAMEILRT 259

Query: 207 AGNLTVELLGRGFAWLDTG 225
            G     ++ RG  + DTG
Sbjct: 260 EGVPVHAIVYRGTRY-DTG 277


>UniRef50_A6TTZ6 Nucleotidyl transferase n=1 Tax=Alkaliphilus metalliredigens QYMF
           RepID=A6TTZ6_ALKMQ
          Length = 825

 Score = 73.2 bits (178), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 51/185 (27%), Positives = 86/185 (46%), Gaps = 5/185 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +K II+AGG GTRL P+T  + K ++PI +KP + Y + +L    I++I  +T       
Sbjct: 4   IKAIIMAGGKGTRLKPLTCNIPKPMVPILNKPTMEYTVELLRKHNIKDIA-VTIAHLPTV 62

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                 DG ++ + L Y  + +P G   +    E F+  + + +VL  +          +
Sbjct: 63  ITDYFHDGGKWDVNLSYYTEETPLGTGGSVKNAEEFI--DDTFIVLSGDSLTDINIKKAI 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
                +   AT+       P  +GVV  +DN R     EKP   +  SN   TG+Y  + 
Sbjct: 121 EFHKNKGSKATLILKNEQMPIEYGVVITNDNGRITRFLEKPSWGEVFSNTINTGMYILEP 180

Query: 179 KVVEY 183
           +V++Y
Sbjct: 181 EVLDY 185


>UniRef50_A8GZ91 Nucleotidyl transferase n=5 Tax=Gammaproteobacteria
           RepID=A8GZ91_SHEPA
          Length = 397

 Score = 72.8 bits (177), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 66/256 (25%), Positives = 113/256 (44%), Gaps = 34/256 (13%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+ILA G GTR+ PI+  + K ++PI  KP++   + +    GI +I +I T      
Sbjct: 1   MKGMILAAGKGTRIKPISYAIPKPMVPILGKPVMESMIQLFAKHGIDKI-VINTSHLAEI 59

Query: 61  FQRLLGDGSEFGIQLEY---AEQPSPDGLAQAF--------------IIGETFLNGEPSC 103
            +   GDG  F +QL Y   A++ + + ++QA                  ETF+      
Sbjct: 60  IESYFGDGHHFNVQLSYSYEAKEVNGEYISQALGSAGGMRKIQDFSGFFDETFV------ 113

Query: 104 LVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQVMDPE--RFGVVEFDDNFRAISLEEKP 161
           +V GD  +        + H  +    AT+   +V   E  ++GVV  D + +  S +EKP
Sbjct: 114 VVCGD-AWIDLDLKQAIEHHKSHGGLATIITREVASSEVSKYGVVVTDKHNQVTSFQEKP 172

Query: 162 KQPK--SNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGF 219
            + +  SN   TG+Y ++  + ++  +       E +I S     L      +  +   F
Sbjct: 173 AEDEALSNRINTGIYIFEPAIFDFIPK-----DVEFDIGSDLFPLLVERQANLYAINMDF 227

Query: 220 AWLDTGTHDSLIEAST 235
            WLD G    + E ++
Sbjct: 228 QWLDVGKVKDVWEVTS 243


>UniRef50_A5YSR1 Sugar nucleotidyltransferase II n=1 Tax=uncultured haloarchaeon
           RepID=A5YSR1_9EURY
          Length = 233

 Score = 72.8 bits (177), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 59/212 (27%), Positives = 96/212 (45%), Gaps = 12/212 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M  ++ A G GTRL  +T    K L+ I  +P++ Y LS  + AG  E+++I   E    
Sbjct: 1   MHAVVPAAGQGTRLGELTDNQPKGLVDIGGQPLLAYVLSTAIEAGADELIVIIGYEAAQI 60

Query: 61  FQRLLGDGSEF-GIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK 119
             R    G  F G+ + Y  Q    GL  A +  E+ ++G+   L+ GDN+F  +   P 
Sbjct: 61  IDRF---GDVFDGVPITYIHQREQLGLGHAVLQAESQIDGD-FLLLNGDNVFT-RSVGPI 115

Query: 120 LRHVAARTEGATVFGYQVMDP---ERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFY 176
              V A      V G + + P   +  GV++ D       + EKP  P S    TG Y  
Sbjct: 116 ---VDASERFDAVLGVEEVSPAVAQTTGVIQTDQTGNVSDIVEKPADPSSTLVTTGCYLL 172

Query: 177 DSKVVEYAKQVKPSERGELEITSINQMYLEAG 208
             ++    + ++PS  GE +++    + + AG
Sbjct: 173 PEEIFMACELLQPSAEGEYQLSEAVGLLVHAG 204


>UniRef50_C6HYP8 UTP-glucose-1-phosphate uridylyltransferase n=1 Tax=Leptospirillum
           ferrodiazotrophum RepID=C6HYP8_9BACT
          Length = 308

 Score = 72.4 bits (176), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 68/269 (25%), Positives = 114/269 (42%), Gaps = 43/269 (15%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K +    G GTR  P+T+   K++LP+ DKP++ Y +   + AGI +++++T     G  
Sbjct: 7   KAVFPLAGHGTRFLPMTKSSPKEMLPVIDKPVVQYVVEEAVAAGIEQMVMVT-----GRG 61

Query: 62  QRLLGDGSEFGIQLE-------------------------YAEQPSPDGLAQAFIIGETF 96
           +R + D  +   +LE                         Y  Q    GL  A +  E  
Sbjct: 62  KRAIEDHFDISYELEDVLKKKNKHALLSELQKISNLAQILYLRQKEALGLGHAVLCAELA 121

Query: 97  LNGEPSCLVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQ---VMDPERFGVVEFDDN-- 151
           +  EP  + LGD I  G     +    A R  GA V G Q   + +   +G+V   +   
Sbjct: 122 VGDEPFAVALGDEILDGPKSGIEQLMEAYRELGAPVIGMQRVPLSEVSHYGIVAGGEIRP 181

Query: 152 --FRAISLEEKPK--QPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEIT-SINQMYLE 206
             FR   L EKP+     S++A+ G Y     V +  +  +P   GE+++T ++N +   
Sbjct: 182 GLFRVERLVEKPRIEDAPSDFAIIGRYLLTPDVFDILRTQRPGVGGEIQLTDALNTLAAN 241

Query: 207 AGNLTVELLGRGFAWLDTGTHDSLIEAST 235
                +E+ G  F   DTG     ++A+ 
Sbjct: 242 RPVYALEIKGDRF---DTGDKMGFLKATV 267


>UniRef50_C0QWA5 Nucleotidyltransferase n=2 Tax=Brachyspira RepID=C0QWA5_BRAHW
          Length = 328

 Score = 72.0 bits (175), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 69/247 (27%), Positives = 116/247 (46%), Gaps = 29/247 (11%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLS-VLMLAGIREILIITTPEDKG 59
           MK II A G GTRL P T    K +LPI    +I + ++ +  +  + E++ I      G
Sbjct: 1   MKVIIPAAGEGTRLRPHTITKPKPILPIAGSTIIDFIMTEISSIQDLDEVIFIV-----G 55

Query: 60  YFQRLLGD---GSEFGIQLEYAEQPSPDGLAQAF-IIGETFLNGEPSCLVLGDNIFFGQG 115
           Y +  + +        I+L + EQ    GLA A  +  E   + +   ++LGD IF    
Sbjct: 56  YLKDQMIEYLTNKYTNIKLTFVEQKEYKGLAHAISLTKEHIKDDDKIFIILGDTIF---- 111

Query: 116 FSPKLRHVAARTEGATVFGY-QVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLY 174
               L ++ ++ E +   G  +V +P RFGV   ++      L EKPK+P SN A+TG+Y
Sbjct: 112 -KLNLSNIVSKNENS--LGVCEVDNPSRFGVAILNEQGVITKLVEKPKEPISNLALTGMY 168

Query: 175 -FYDSK----VVEYAKQVKPSERGELEITSINQMYLEAGNL--TVELLGRGFAWLDTGTH 227
              ++K     ++Y  +     + E ++T   +  +E   +  T +L G    W D G  
Sbjct: 169 NIVNTKELFEAIDYIIKNDIKTKNEYQLTDALEYMIEKSIVFKTFKLDG----WYDCGEK 224

Query: 228 DSLIEAS 234
            ++IE +
Sbjct: 225 STMIETN 231


>UniRef50_Q30U75 Nucleotidyl transferase n=3 Tax=Proteobacteria RepID=Q30U75_SULDN
          Length = 234

 Score = 72.0 bits (175), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 62/217 (28%), Positives = 91/217 (41%), Gaps = 17/217 (7%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ ++LA G G+RL PIT  + K L+PI  KP++ Y L  L  AGI E LI T       
Sbjct: 1   MRALLLAAGIGSRLRPITNTIPKCLVPINGKPLLEYWLKNLSEAGIDEFLINTHHLHVQV 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            + +        I L Y ++    G     +    F + EP  LV  DN+ F   F   +
Sbjct: 61  EEFIESSKYRDKITLVYEKKLLNTG--STLLTNRAFFDNEPFMLVHADNLSFCD-FGKFI 117

Query: 121 RHVAARTEGA--TVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYF--- 175
                R      T+  ++  +P   G+VE D+        EK K P SN A   +Y    
Sbjct: 118 NAHKNRPNNCDITMMLFKSDNPSSCGIVELDNRGIVQEFYEKVKNPPSNLANGAVYICEA 177

Query: 176 --------YDSKVVEYAKQVKPSERGELEITSINQMY 204
                    D K ++++  V P   G++  T  N  Y
Sbjct: 178 SLFDFLECLDKKEIDFSNDVLPKYLGKIN-TYFNNTY 213


>UniRef50_Q28JE9 Nucleotidyl transferase n=1 Tax=Jannaschia sp. CCS1
           RepID=Q28JE9_JANSC
          Length = 240

 Score = 72.0 bits (175), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 53/183 (28%), Positives = 84/183 (45%), Gaps = 8/183 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +K ++LAGG GTRL P+T  + K L+P+  KP++ Y L  L  A IR+ L+ T  +    
Sbjct: 4   VKALLLAGGLGTRLRPLTDTLPKCLIPVAGKPILDYWLDALDAADIRQALLNTHHKRDQV 63

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVL-GDN---IFFGQGF 116
              L    S   + +  A +P   G A        + +     +V+  DN   I  G   
Sbjct: 64  KIWLETANSSRNVAIAEAYEPELLGSAGTVTANRDWADDASEVVVIYADNLSDIDLGALV 123

Query: 117 SPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFY 176
           +    H    ++  T+  +    P + G+   DD+ R  +  EKP QP+S+ A  GLY  
Sbjct: 124 AFHRTH----SDPMTMMLFHTPYPSKCGIATLDDDARVTAFVEKPDQPESDLANAGLYVL 179

Query: 177 DSK 179
           D+ 
Sbjct: 180 DAS 182


>UniRef50_B0BZ78 Nucleotidyl transferase protein n=5 Tax=Cyanobacteria
           RepID=B0BZ78_ACAM1
          Length = 323

 Score = 72.0 bits (175), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 44/150 (29%), Positives = 72/150 (48%), Gaps = 2/150 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +I+AGG GTRL P+T    K +LP++++P + + +      G+ +IL +        
Sbjct: 1   MQAVIIAGGKGTRLSPLTLRSPKPMLPLFERPFLSWMVERCKAVGLTDIL-MNIRYQATQ 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            Q   GDG +FG+++ Y  +      A A  + E F  GEP  +V   +I         +
Sbjct: 60  IQEYFGDGQKFGVKIRYVIEKEALDTAGAMKLAEPFYTGEP-LVVFNADILTNLNLQALM 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDD 150
           +        AT+   +V DP  FG+VE  D
Sbjct: 119 QAHEQTQAQATIALARVADPTAFGLVELTD 148


>UniRef50_D2EFH1 Nucleotidyl transferase n=1 Tax=Candidatus Parvarchaeum acidiphilum
           ARMAN-4 RepID=D2EFH1_9EURY
          Length = 326

 Score = 71.6 bits (174), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 72/276 (26%), Positives = 122/276 (44%), Gaps = 45/276 (16%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKG-- 59
           KG+ILA G+GTR  P +  + K +LP+   PM    +  ++ AGI++ILI++  + +G  
Sbjct: 7   KGVILASGNGTRARPASYYIPKPMLPLGQIPMTKRIVYQMINAGIKDILIVSRNDKEGLP 66

Query: 60  -------YFQR--LLGDGSEFGIQLEYAE-------QP------SPDGLAQAFIIG--ET 95
                  YF++  +  + SE+  ++E  E       QP       P G A++  +     
Sbjct: 67  SFSMLIDYFRKENVANNLSEYKNKIENGEIKISLDYQPVNSKNGKPLGTAKSLKVAYDHG 126

Query: 96  FLNGEPSCLVLGDNIFFGQGF---SPKLRHVAARTEGATVFGYQVMDPERFG------VV 146
           FLNGEP  ++  D     Q F      L  + ++ +G T+   +  + +R          
Sbjct: 127 FLNGEPCAVMFSD--VLQQNFKGGKSLLEQMLSKYDGKTLVSMKRNNVKRITEKSAAYCS 184

Query: 147 EFDDNFRAIS--LEEKP-----KQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITS 199
             + NF  +   LE+ P     K P       G+Y  D K  +  ++VK    GE  IT 
Sbjct: 185 NIEGNFYKLDEVLEKPPLEYVNKHPTDLSVAGGIYLIDEKGADKVRKVKKGAGGEYHITD 244

Query: 200 INQMYLEAGNLTVELLGRG-FAWLDTGTHDSLIEAS 234
           I     ++G++   L+ +  F   D G  D LI+ +
Sbjct: 245 IIDQEAKSGDVYGYLIDKNEFKSYDVGEFDVLIKEN 280


>UniRef50_C8NLU6 Mannose-1-phosphate guanyltransferase n=88 Tax=Actinomycetales
           RepID=C8NLU6_COREF
          Length = 372

 Score = 71.6 bits (174), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 51/194 (26%), Positives = 89/194 (45%), Gaps = 4/194 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +  +IL GG GTRL P+T    K +LP    P + + L+ +  AGI  +++ T+ + +  
Sbjct: 20  VDAVILVGGKGTRLRPLTNNTPKPMLPTAGHPFLKHLLARIKAAGITHVVLGTSFKAE-V 78

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F+   GDGS+ G+++EY  +  P G           L  + + +  GD +  G      L
Sbjct: 79  FEDYFGDGSDLGLEIEYVVEDQPLGTGGGIRNVYDKLRHDTAVVFNGD-VLSGADLGDIL 137

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                +    T+   +V +P  FG V  D + R +   EK + P ++    G Y +  ++
Sbjct: 138 ATHREKEADLTMHLVRVANPRAFGCVPTDADGRVLEFLEKTEDPPTDQINAGCYVFQREL 197

Query: 181 VEY--AKQVKPSER 192
           +    A +V   ER
Sbjct: 198 IASIPADRVVSVER 211


>UniRef50_D2LMS9 Nucleotidyl transferase n=3 Tax=Aciduliprofundum boonei T469
           RepID=D2LMS9_9EURY
          Length = 385

 Score = 71.6 bits (174), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 58/189 (30%), Positives = 92/189 (48%), Gaps = 30/189 (15%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITT-PEDKG 59
           M+ IILA G G RL P+T  + K +LP+ +KP++ Y +  L    I++I I+     DK 
Sbjct: 1   MRAIILAAGEGIRLRPLTTYMPKVMLPVGNKPILEYIIESLHENSIKDITIVVGYKSDK- 59

Query: 60  YFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFI---IGETFLNGEPSCLVLGDNIFFGQGF 116
             ++  G+GS+FG+ ++Y EQ    G A A     I E FL      L  GDNI  G+  
Sbjct: 60  -IKQYFGNGSDFGVHIDYVEQKKQLGTAHALYQARIEEEFL------LFFGDNI-VGEKC 111

Query: 117 SPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNW-----AVT 171
             +L +    T+  T+ G        +G+VE        ++  K K  + +W     A T
Sbjct: 112 VKELLN----TKINTIIGAHSNKTSVYGIVE--------NVNGKIKIVRKSWDGEAIAFT 159

Query: 172 GLYFYDSKV 180
           G+  +D ++
Sbjct: 160 GMGHFDGEI 168


>UniRef50_Q2LPS3 Glucose-1-phosphate adenylyltransferase n=3 Tax=cellular organisms
           RepID=Q2LPS3_SYNAS
          Length = 240

 Score = 71.2 bits (173), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 72/243 (29%), Positives = 114/243 (46%), Gaps = 30/243 (12%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++LAGG G RL P T+ + K L+PI D P++   L  + +AGI  + I+T       
Sbjct: 1   MKAVVLAGGKGARLAPYTKILPKPLMPIGDMPILEVLLRQMKVAGIDHV-ILTVGHLSEL 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQ--AFIIG--ETFL--NGEP-SCLVLGDNIFFG 113
            +    DGS+FG+ + Y+ +  P G A   + I G  ETFL  NG+  + L L + I F 
Sbjct: 60  LRAFFQDGSQFGVDISYSYEKCPLGTAGPISLIDGLDETFLVTNGDVLTTLSLRELIGFH 119

Query: 114 QGFSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVT-G 172
           +           +   AT+  +Q       GV++++ N+      EKP     ++ V+ G
Sbjct: 120 R----------EQKAAATIAVHQRQTKIDLGVIQWNGNYEVKGYIEKPVY---DYTVSMG 166

Query: 173 LYFYDSKVVEYAKQVKPSERGE-LEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLI 231
           +Y ++ KV+ Y         GE L+   + +  + AG   V     G+ W D G  D   
Sbjct: 167 VYVFEPKVLSYIPH------GEYLDFPDLVKKLIAAGEKVVGYRFHGY-WEDLGRPDDYE 219

Query: 232 EAS 234
            AS
Sbjct: 220 RAS 222


>UniRef50_A5URP0 Nucleotidyl transferase n=6 Tax=Bacteria RepID=A5URP0_ROSS1
          Length = 331

 Score = 71.2 bits (173), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 67/245 (27%), Positives = 105/245 (42%), Gaps = 23/245 (9%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK II   G GTRL P T    K L+ +  KP++ + L  L    I E++ IT     GY
Sbjct: 1   MKVIIPTAGLGTRLRPHTYSKPKPLVSVAGKPVLGHILDTLTRFPIDEMIFIT-----GY 55

Query: 61  FQRLLGD--GSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSP 118
               + D   S + I   + EQ    G A A  +    ++G P+ ++  D I     F  
Sbjct: 56  LGNQIADYVTSNYKIPARFIEQTELKGQAHAVYLAREVVSG-PTIILFVDTI-----FEA 109

Query: 119 KLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDS 178
            L  +  +     +F  +V DP RFGV    D F    L EKP   +S  A+ GLY+   
Sbjct: 110 DLSRLTEQDIDGAIFCKEVDDPRRFGVAFTKDGF-ITRLVEKPATDESKLAMIGLYYIRD 168

Query: 179 -----KVVEYAKQVKPSERGELEITSINQMYLEAG-NLTVELLGRGFAWLDTGTHDSLIE 232
                + +E         +GE  +T   Q+ +E G   T   +     W D G  +++++
Sbjct: 169 IQWLMRAIEVLMLRNIQTKGEYFLTDALQLMVENGARFTAPTVD---VWEDCGKPETVLQ 225

Query: 233 ASTFV 237
            + ++
Sbjct: 226 TNRYL 230


>UniRef50_Q9YCQ9 Putative nucleotidyl transferase n=1 Tax=Aeropyrum pernix
           RepID=Q9YCQ9_AERPE
          Length = 416

 Score = 71.2 bits (173), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 56/231 (24%), Positives = 101/231 (43%), Gaps = 7/231 (3%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQR 63
           ++LAGG G RL P++   +K L+PI  +P++   L + +  G+ +  ++      G    
Sbjct: 7   VVLAGGRGERLWPVSETRAKPLVPILGEPLVCRHLRLGLATGLFDEAVVLVGYRGGEVVE 66

Query: 64  LLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHV 123
            +     FG  + + EQ    G   A       L GE     +  +++    F   L   
Sbjct: 67  AV-RACGFG-GVRFVEQGGALGTGHAVRRVLEELGGEGVFTFVYGDVYLDSRFYGLL--- 121

Query: 124 AARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEY 183
            A  E  +V    V D   +G+++  D      + EKP++P+  W   G +  D   +  
Sbjct: 122 -ASAEAPSVLAGWVEDARWYGLLDVGDGL-VRGVVEKPREPRGGWVFLGGFKVDGSFLGL 179

Query: 184 AKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
            + ++PS RGE+E+T   +     G L   + G G+ W+D G    ++ A+
Sbjct: 180 LRGLEPSPRGEVEVTDALEALAREGVLRALVGGEGWGWVDVGRPWDVLRAN 230


>UniRef50_A6UTZ2 UTP-glucose-1-phosphate uridylyltransferase n=9 Tax=Methanococcales
           RepID=A6UTZ2_META3
          Length = 285

 Score = 70.9 bits (172), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 62/229 (27%), Positives = 97/229 (42%), Gaps = 35/229 (15%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIIT-------- 53
           K +I A G GTRL P+T+   K++L + DKP+I Y +  L  A +  ILI+T        
Sbjct: 7   KAVIPAAGFGTRLLPLTKAKPKEMLSVVDKPIIQYVIEDLADASVDNILIVTGKGKSAIE 66

Query: 54  TPEDKGY-FQRLLGDGSEFGI-----------QLEYAEQPSPDGLAQAFIIGETFLNGEP 101
              D+ Y  +  L +G +  +            + Y  Q    GL  A   G+ F+  E 
Sbjct: 67  NHFDRNYGLENKLKEGGKTELLNIIGKIDNLANIFYTRQKQQKGLGDAIYCGKEFVGKEY 126

Query: 102 SCLVLGDNIFFGQGFSPKLRH---------VAARTEGATVFGYQVMDPERF--GVVEFDD 150
              ++GD I+ G      L           V  R     V+ Y V+  +    G+ E DD
Sbjct: 127 FLALVGDTIYTGNVVQKMLEVYEKYRCSVIVLERVPKELVYKYGVISGKEIEEGIFELDD 186

Query: 151 NFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITS 199
                S+E  P    SN  +TG Y    K+ ++ + ++    GEL++T 
Sbjct: 187 LVEKPSVEGAP----SNLIITGAYLLSPKIFDHLETIEIGAGGELQLTD 231


>UniRef50_Q5UXR9 Glucose-1-phosphate thymidylyltransferase n=2 Tax=Halobacteriaceae
           RepID=Q5UXR9_HALMA
          Length = 396

 Score = 70.9 bits (172), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 57/225 (25%), Positives = 105/225 (46%), Gaps = 16/225 (7%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            ++LA G GTRL P+TR   K +LP  ++P++ +    L+ AGI +++++      GY +
Sbjct: 6   AVVLAAGEGTRLRPLTRNRPKPMLPAANRPILEHVFDALVEAGIEKLVVVV-----GYKR 60

Query: 63  RLLGD--GSEF-GIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK 119
             + D  G  + G+ + Y  Q    G   A +   + ++G P  ++ GD +        +
Sbjct: 61  DRVQDHFGPTYRGVPISYVSQTKQLGSGHALLQARSVVDG-PVLVMNGDRLVDAATIE-E 118

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSK 179
           +    A T   ++   +  D  R+G VE  D    + + EKP+  +      G+Y +D  
Sbjct: 119 VDTSYAETGNTSIAVLERQDTSRYGAVEVQDR-DIVDIVEKPQHDEFRLINGGVYAFDGD 177

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNL-TVELLGRGFAWLD 223
           + E   +      GEL +T   ++ LE+  +  VE+ G    W+D
Sbjct: 178 IFEAIDETT-RHAGELALTDTIELLLESDRVQAVEVDG---MWVD 218


>UniRef50_A0B7L5 Nucleotidyl transferase n=1 Tax=Methanosaeta thermophila PT
           RepID=A0B7L5_METTP
          Length = 403

 Score = 70.9 bits (172), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 68/242 (28%), Positives = 112/242 (46%), Gaps = 20/242 (8%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGI-REILIITTPED-- 57
           M+ IILA G G+R+ P+T    K +LP+   P++   +     AGI R + ++    D  
Sbjct: 4   MQAIILAAGEGSRMRPLTASRPKVMLPVGGAPLLEELVLRCREAGINRFVFVVGYRRDVV 63

Query: 58  KGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
             YF+    DGS+F + + YA Q    G   A +     L+ +   ++ GD +   Q   
Sbjct: 64  TSYFK----DGSDFDVDISYAVQEKQLGTGHALMTARD-LSDDRFFVINGDVLPDVQA-- 116

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYD 177
             LR + +  E  +V  ++V++  R+GV    D      +E+ P  P S+ A  G+Y  D
Sbjct: 117 --LRRMIS-MEDLSVATHRVVEASRYGVFLLRDGLVEGVVEKSP-SPPSDMANAGIYLLD 172

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGN--LTVELLGRGFAWLDTGTHDSLIEAST 235
            ++ E  ++V  S RGE E+T        AG     +EL      W++ G    ++ AS 
Sbjct: 173 REIFELMEEVPVSIRGEYELTDGINALASAGRKIWAIEL----SEWVEVGVPWDILTASN 228

Query: 236 FV 237
            V
Sbjct: 229 AV 230


>UniRef50_C8PUN5 Utp--glucose-1-phosphate uridylyltransferase n=1 Tax=Enhydrobacter
           aerosaccus SK60 RepID=C8PUN5_9GAMM
          Length = 295

 Score = 70.9 bits (172), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 67/279 (24%), Positives = 118/279 (42%), Gaps = 45/279 (16%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKG--- 59
            +I   G GTR+ P+++ V K+LLP+ +KP I Y +   + AG+  I+++   +  G   
Sbjct: 8   AVIPVAGFGTRMLPLSKAVPKELLPLGNKPAIQYVVEEAIAAGLTNIVLVNHAQKTGIEN 67

Query: 60  YFQ-------RLLGDGSE----------FGIQLEYAEQPSPDGLAQAFIIGETFLNGEPS 102
           YF        +L G G              + +    Q  P GL  A +     +  EP 
Sbjct: 68  YFDINSELDTQLRGKGKAALADSLNWLPAEVTVTSVRQGKPLGLGHAVLQARPIVGDEPF 127

Query: 103 CLVLGDNI-------FFGQGFSPKLRHVAARTEGATVFG-YQVMDPERFGVV-------- 146
            ++L D I       +  Q  +  L+  A +     +    +  D  ++G+         
Sbjct: 128 AVLLPDVILNPYNTDYTQQNLAYMLQQFAKQQHSQILVDPVKESDISKYGIAKLASTQMV 187

Query: 147 ---EFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEIT-SI 200
              E + +F      EKPK     SN AV G Y +++ + +Y    +PS  GE+++T +I
Sbjct: 188 AKSEQNQSFAVTGFVEKPKAEDAPSNLAVVGRYVFNNAIFDYLANTQPSVGGEIQLTDAI 247

Query: 201 NQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           + +    G   V ++G  F   D G  +S ++A  +  T
Sbjct: 248 DALISTQGVDVVSMVGNSF---DAGDMNSYLQAVGYFAT 283


>UniRef50_A8V905 UTP-glucose-1-phosphate uridylyltransferase n=3 Tax=Bacteria
           RepID=A8V905_NEIME
          Length = 287

 Score = 70.5 bits (171), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 59/232 (25%), Positives = 100/232 (43%), Gaps = 39/232 (16%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIIT-----TPE 56
           K +    G GTR  P T+  +K++LPI DKP+I Y     + AG  E++ IT       E
Sbjct: 6   KAVFPVAGMGTRFLPATKASAKEMLPIVDKPLIQYAAEEAVAAGCTELIFITGRNKRNIE 65

Query: 57  DK--------------------GYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETF 96
           D                     GY Q++L D     +   +  Q    GL  A +     
Sbjct: 66  DHFDKAYELETELEMREKHKLLGYVQKILLD----HVSCIFIRQAEALGLGHAVLCARPA 121

Query: 97  LNGEPSCLVLGDNIFFG-QGFSPKLRHVAARTEGATVFGYQVMDPER---FGVVEFD--- 149
           +  EP  ++L D++    QG   ++  +  ++ G ++ G + +DP +   +G+VE +   
Sbjct: 122 VGNEPFAVILADDLIDAPQGALKQMVDIYNQS-GNSILGVETVDPSQTGSYGIVEVEQLK 180

Query: 150 DNFRAISLEEKPK--QPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITS 199
              R  ++ EKPK     SN AV G Y    ++ +    +     GE+++T 
Sbjct: 181 SYQRVTNIVEKPKPEDAPSNLAVVGRYILTPRIFDLLTNLPRGAGGEIQLTD 232


>UniRef50_B0R8I5 Sugar nucleotidyltransferase n=2 Tax=Halobacterium salinarum
           RepID=B0R8I5_HALS3
          Length = 395

 Score = 70.5 bits (171), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 64/254 (25%), Positives = 112/254 (44%), Gaps = 19/254 (7%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ ++LA G G RL P+T    K ++P+ ++P++ + +  L+ AG+  ++++    ++  
Sbjct: 1   MQAVVLAAGKGERLWPLTENRPKPMVPVANQPILEHIVDALVSAGVTRVMLVVG-SNRER 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            QR   DGS +GI++ Y  Q    G   A    E+ + GE    + GD +          
Sbjct: 60  VQRHFEDGSRWGIEISYVVQDRQLGTGHALAQAESVV-GESFVALNGDRVIDASLVEDVW 118

Query: 121 RHVAARTEGATVFGY-QVMDPERFGVVEFD-DNFRAISLEEKPKQPKSNWAVTGLYFYDS 178
                R  G +  G  QV  P  +GVV+ D      I  +  P+   S +   G+Y +  
Sbjct: 119 E--CHRESGDSAMGVTQVETPSAYGVVDLDGGTVTDIDEQPVPELVASEYINAGVYAFGP 176

Query: 179 KVVEYAKQVKPSERGELEIT-SINQMYLEAGNLTVELLGRGFAWLD-------TGTHDSL 230
            V  +A   +    GEL +T ++++   +     V   GR   WLD          + +L
Sbjct: 177 SV--FAAIRRTDSYGELALTDALDEQLADHELRAVRYDGR---WLDVSEPWDLVAANSAL 231

Query: 231 IEASTFVQTVEKRQ 244
           I    F   VE+R+
Sbjct: 232 ITDRRFDPPVERRK 245


>UniRef50_B0PFA5 Putative uncharacterized protein n=1 Tax=Anaerotruncus colihominis
           DSM 17241 RepID=B0PFA5_9FIRM
          Length = 772

 Score = 70.1 bits (170), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 58/192 (30%), Positives = 83/192 (43%), Gaps = 21/192 (10%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIRE-ILIITTPEDK- 58
           MK +I+AGG GTRL P+T    K +  +  +P++ Y L +L   G+ E +L +    D+ 
Sbjct: 1   MKAVIMAGGRGTRLRPLTERCPKPMARLCGRPVVEYILELLAKNGVTESVLTLQYLPDQI 60

Query: 59  -GYFQRLLGDGSEFGIQLEYAEQPSPDGLA-----QAFIIGETFLNGEPSCLVLGDNIFF 112
             +F     D S  GI L + E+  P G A      A  IGE         LV+  +   
Sbjct: 61  VSHFP----DNSFAGIALSFCEEAQPLGTAGSVKNAAGQIGEDL-------LVISGDALC 109

Query: 113 GQGFSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAV 170
                  +   AAR    T+   +V DP  +G+V  D +       EKP   Q  S  A 
Sbjct: 110 DFSLREAMDQHAARCADVTIVTARVGDPREYGLVIADSDGHVTGFIEKPSFAQATSELAN 169

Query: 171 TGLYFYDSKVVE 182
           TG+Y      VE
Sbjct: 170 TGIYILSPHAVE 181


>UniRef50_C7ICW0 Nucleotidyl transferase n=1 Tax=Clostridium papyrosolvens DSM 2782
           RepID=C7ICW0_9CLOT
          Length = 815

 Score = 70.1 bits (170), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 55/193 (28%), Positives = 97/193 (50%), Gaps = 11/193 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIRE--ILIITTPE-D 57
           MK +I+AGG G+RL P+T  + K ++P+ +KP++ + + +L   GI +  I ++  P+  
Sbjct: 6   MKAVIMAGGEGSRLRPLTCDLPKPMVPVMNKPVLEHTIGLLKSYGITDIGITLLYHPQII 65

Query: 58  KGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
           K YF    G G   G+ + Y  + SP G A        FL+ E   ++ GD++       
Sbjct: 66  KDYF----GSGHSHGVNIYYFLEESPLGTAGGIKNARDFLD-ETFIVISGDSL-TDLDID 119

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYF 175
             L++  ++   AT+   +V  P  +GVV  D+N       EKP   +  S+   TG+Y 
Sbjct: 120 KALKYHQSKKSIATLILAKVDVPLEYGVVLTDENGSVKGFVEKPSWGEIFSDMVNTGIYI 179

Query: 176 YDSKVVEYAKQVK 188
            + +++ Y +  K
Sbjct: 180 LEPEILSYIESGK 192


>UniRef50_C8NNE5 UTP-glucose-1-phosphate uridylyltransferase n=71
           Tax=Actinomycetales RepID=C8NNE5_COREF
          Length = 314

 Score = 69.7 bits (169), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 65/254 (25%), Positives = 103/254 (40%), Gaps = 43/254 (16%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKG---Y 60
           ++ A G GTR  P T+ V K+LLP+ D P I          G   + +IT P   G   +
Sbjct: 16  VVPAAGMGTRFLPATKTVPKELLPVVDTPGIELIAEEAAKLGATRLAVITAPNKAGVLAH 75

Query: 61  FQRLLGDGSEFGIQLEY---------------------AEQPSPDGLAQAFIIGETFLNG 99
           F+R     +E    LE                        Q  P GL  A  + E+ L+ 
Sbjct: 76  FERF----TELEATLEERGKTDQLQKVRRAAGLIDAVPVTQEHPLGLGHAVGLAESVLDA 131

Query: 100 EPS--CLVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQVMDPER-----FGVVEFDDN- 151
           +     ++L D++    G   ++  V A   G+ +   +V D E      F V   DDN 
Sbjct: 132 DEDVVAVMLPDDLVLPFGVMERMAQVRAEFGGSVLCAVEVADDEVSNYGIFRVENADDNG 191

Query: 152 -----FRAISLEEKP--KQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMY 204
                 R   + EKP  +   SN A TG Y  D  + +  +++ P   GEL++T    + 
Sbjct: 192 ADQDVKRVTGMVEKPAVEDAPSNLAATGRYLLDRSIFDALRRITPGAGGELQLTDAIALL 251

Query: 205 LEAGNLTVELLGRG 218
           ++ G+    ++ RG
Sbjct: 252 IDDGHPVHIVVHRG 265


>UniRef50_B8FX62 Glucose-1-phosphate adenylyltransferase n=2 Tax=Desulfitobacterium
           hafniense RepID=B8FX62_DESHD
          Length = 229

 Score = 69.7 bits (169), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 66/237 (27%), Positives = 103/237 (43%), Gaps = 21/237 (8%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ IILAGG G+RL P +R + K L PI DKP+    +  L  AG  E+++       GY
Sbjct: 1   MQTIILAGGRGSRLDPYSRILPKPLFPIGDKPIAAILIEQLKKAGTDEVIMCL-----GY 55

Query: 61  FQRLLG----DGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGF 116
              LL     DGSEFG+ + Y+ +  P G A      E     + + +V+  +      F
Sbjct: 56  LSDLLKTYFQDGSEFGLTIRYSVESEPLGTAGPLKGVEGL---QDNFVVVNGDELTTLDF 112

Query: 117 SPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFY 176
                H  A     TV   +      FGV+E  D  + I+  EKP    + WA  G+Y  
Sbjct: 113 RALYEHHRAVQADMTVAVQKKTTHSSFGVLEIQDG-QVIAYAEKPTL--NYWASMGIYVI 169

Query: 177 DSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEA 233
           +  ++ Y       +  + ++ ++ Q  ++ G        +   W D GT   L +A
Sbjct: 170 NKDILSYI-----PDNEKYDMPNLVQCLIQNGAKVSSYESQDL-WFDIGTLGDLEKA 220


>UniRef50_Q1AVJ3 Nucleotidyl transferase n=1 Tax=Rubrobacter xylanophilus DSM 9941
           RepID=Q1AVJ3_RUBXD
          Length = 367

 Score = 69.7 bits (169), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 56/189 (29%), Positives = 85/189 (44%), Gaps = 13/189 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +IL GG GTRL PIT  + K L+P+ +KP + Y L  L   GI   ++       GY
Sbjct: 1   MQAVILVGGLGTRLRPITYDIPKALVPLRNKPFMGYTLDFLRGGGIEGAVL-----SLGY 55

Query: 61  F----QRLLGDGSEF-GIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQG 115
                QR + +  +  G  +EYA +  P G A        FL   P  +VL  ++  G  
Sbjct: 56  LPDPIQRYIDERGDLDGFSVEYAVEERPLGTAGGIKNAARFLQDGP-VVVLNGDVLTGMD 114

Query: 116 FSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGL 173
               +    +    AT+    V DP  +G+VE D +       EKP   +  +N    G+
Sbjct: 115 LRKAIELHRSTGALATITLTSVEDPTAYGLVEVDHDMMVRRFIEKPSPDEVTTNLVNAGV 174

Query: 174 YFYDSKVVE 182
           Y  + +V+E
Sbjct: 175 YVLEPEVLE 183


>UniRef50_C5A4I2 Sugar-phosphate nucleotydyltransferase n=9 Tax=Thermococcaceae
           RepID=C5A4I2_THEGJ
          Length = 420

 Score = 69.3 bits (168), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 61/210 (29%), Positives = 95/210 (45%), Gaps = 9/210 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++LA G G RL P+T    K +L + ++P+I Y +  L    + E +I+   E +  
Sbjct: 1   MKAVVLAAGKGERLKPLTDDRPKVILKVANRPIIEYVMENL-YPFVDEFIIVVRYEKEKI 59

Query: 61  FQRLLGDGSEFGIQ-LEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK 119
            + L   G EFG + + Y EQ   +G A+A       +  E   +  GD  F  +     
Sbjct: 60  IETL---GDEFGGKPVTYVEQRPGEGTAKAVESAREHVGDEEFIVANGDIYFEVEAIKEL 116

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP-KQPKSNWAVTGLYFYDS 178
           +         A +      D   FG VE  +  R + + EKP K P   +A  G+Y +  
Sbjct: 117 VSAFRREKADAALVLKHFEDLSHFGKVEVKEG-RVVGILEKPGKVP--GYANLGIYLFRP 173

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAG 208
            V E+  +   SERGE EIT    + ++AG
Sbjct: 174 DVFEFIGETPLSERGEYEITDTINLMIKAG 203


>UniRef50_A2EDD6 Nucleotidyl transferase family protein n=2 Tax=Trichomonas
           vaginalis RepID=A2EDD6_TRIVA
          Length = 352

 Score = 69.3 bits (168), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 66/251 (26%), Positives = 110/251 (43%), Gaps = 16/251 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +  ++L GG GTRL P+T   SK L+   +K M  + L  L+ A  ++I I+   E +  
Sbjct: 8   LAALVLVGGFGTRLRPLTFTCSKPLVEFCNKHMCEFMLDALVAANCKKI-ILALSELQDD 66

Query: 61  FQRLLGD--GSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSP 118
            +R +     +  GI++  + +  P G A    +    L G     +L  +I     F+ 
Sbjct: 67  LKRFIESYQQAHPGIEVIPSIEIEPLGTAGPIALARKHLKGH-RFFMLNSDIMSIYPFTD 125

Query: 119 KLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVT-GLYFYD 177
            L++       AT+    V D  R+GV++ D         EKP +   N A+  G Y  +
Sbjct: 126 LLKYHMNHDGEATIMSINVEDGSRYGVIDSDAEGVVTGFREKPTENNKNVAINAGHYILE 185

Query: 178 SKVVEYAKQVKPSERGEL--EITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAST 235
             VV+   +   S   E+  EI S  Q+++      ++L G    W+D GT  + +EA  
Sbjct: 186 PSVVDLIPEKFCSIEREIFPEIASRKQLHV------MKLQGH---WMDIGTPQAFLEAIP 236

Query: 236 FVQTVEKRQGF 246
             +   K Q F
Sbjct: 237 LAKETLKIQSF 247


>UniRef50_C1VEK9 Nucleoside-diphosphate-sugar pyrophosphorylase family protein n=1
           Tax=Halogeometricum borinquense DSM 11551
           RepID=C1VEK9_9EURY
          Length = 390

 Score = 69.3 bits (168), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 63/226 (27%), Positives = 109/226 (48%), Gaps = 11/226 (4%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           + ++LA G G RL P+T+ + K +LP+ ++P+I Y L  L+ +GI  ++++         
Sbjct: 6   EAVVLAAGEGRRLRPLTKYLPKPMLPVANRPVIDYVLDALVESGIERVVVVVGYRGDRIQ 65

Query: 62  QRLLGDGSEF-GIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
             L    +E+ G  +E+ +QPS  G   A +     +NGE   +V GD+I      +  L
Sbjct: 66  THLT---AEYKGANIEFVQQPSRLGSGHALLQATGMVNGE-FLVVNGDSIINAAIVTSTL 121

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
               +    ATV       PE +GVV  +    A  ++E P + +      G+Y +D  V
Sbjct: 122 ERYDSTDCAATVAVAHSDTPEEYGVVITNRGLIA-DIDEHPVEREGYVVNAGVYVFDESV 180

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGT 226
                + +P + GE+ +T   + +L+ G +T  L+  G  WLD  T
Sbjct: 181 FAALDRTEPWQ-GEIRLTDAIE-HLD-GPVTSILVNGG--WLDPST 221


>UniRef50_P0C0I9 UTP--glucose-1-phosphate uridylyltransferase 1 n=116 Tax=cellular
           organisms RepID=HASC1_STRP1
          Length = 304

 Score = 69.3 bits (168), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 65/252 (25%), Positives = 110/252 (43%), Gaps = 39/252 (15%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIIT-----TPE 56
           K II A G GTR  P T+ ++K++LPI DKP I + +   + +GI EIL++T     + E
Sbjct: 6   KAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEEALKSGIEEILVVTGKAKRSIE 65

Query: 57  D--------------KGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPS 102
           D              KG  + L        I L +  Q  P GL  A +  + F+  EP 
Sbjct: 66  DHFDSNFELEYNLQAKGKNELLKLVDETTAINLHFIRQSHPRGLGDAVLQAKAFVGNEPF 125

Query: 103 CLVLGDNIF-----FGQGFSPKLRHVAARTEGATVFGYQV--MDPERFGVVEFDDN---- 151
            ++LGD++        +  + +L     +T  +T+   +V   D   +GV+         
Sbjct: 126 VVMLGDDLMDITNASAKPLTKQLMEDYDKTHASTIAVMKVPHEDVSSYGVIAPQGKAVKG 185

Query: 152 -FRAISLEEKPKQPK---SNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEA 207
            +   +  EKP QP+   S+ A+ G Y    ++    ++  P    E+++T      ++ 
Sbjct: 186 LYSVDTFVEKP-QPEDAPSDLAIIGRYLLTPEIFGILERQTPGAGNEVQLTDA----IDT 240

Query: 208 GNLTVELLGRGF 219
            N T  +  R F
Sbjct: 241 LNKTQRVFAREF 252


>UniRef50_D0JBR7 UTP-glucose-1-phosphate uridylyltransferase n=2 Tax=Blattabacterium
           RepID=D0JBR7_BLASB
          Length = 338

 Score = 68.9 bits (167), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 59/254 (23%), Positives = 110/254 (43%), Gaps = 16/254 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLS----VLMLAGIREILIITTPE 56
           MK II   G G RL+P T    K  + I  K ++   +     V+ +  ++EI+ I    
Sbjct: 1   MKIIIPMAGKGLRLYPHTLSTPKAFIHIAGKTILRRLVESFSEVIKIFSVQEIIFIIGNN 60

Query: 57  DKGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGF 116
                 +L+   ++ G+      Q +P G A A +  +  LNGEP  +   D +F     
Sbjct: 61  VGNIETKLIKLANDIGVHPIIYYQITPLGTADALLRAKDSLNGEPVIIAFSDTLFDNTSL 120

Query: 117 SPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFY 176
             ++ +         ++  +V +P  FGVV+ D +       EKP    SN A+ GLY++
Sbjct: 121 EKEITNQVDNI----IWTKKVQNPHLFGVVKCDSSGIVTHFIEKPNNYVSNLAIIGLYYF 176

Query: 177 DS-----KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLI 231
            +     K +E ++ +  +   E ++TS+ +   + G        +G  W+D G     I
Sbjct: 177 KNSLFLRKELE-SQSISYNNNQEYQLTSVLENMRKKGERFTYKQVKG--WMDFGDQKRTI 233

Query: 232 EASTFVQTVEKRQG 245
            +++ + ++E    
Sbjct: 234 SSNSKILSIESNHS 247


>UniRef50_B5HPZ4 Nucleotide phosphorylase n=1 Tax=Streptomyces sviceus ATCC 29083
           RepID=B5HPZ4_9ACTO
          Length = 365

 Score = 68.9 bits (167), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 57/191 (29%), Positives = 87/191 (45%), Gaps = 17/191 (8%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           + IIL GG GTRL P+T    K LL +     I + ++ LM AG+  ++  T+     Y 
Sbjct: 3   EAIILVGGKGTRLRPLTNHTPKPLLGVAGSSFIRHQIAKLMDAGVEHVVFATS-----YL 57

Query: 62  QRLLGDGSEFG-----IQLEYAEQPSPDGLAQAFIIGETFLNG--EPSCLVLGDNIFFGQ 114
             L  +  EF      +++ YA +  P G   A       L+G  + S LVL  +I  G 
Sbjct: 58  ASLFEE--EFKDFTRELKISYAVEEVPLGTGGAIRNAARLLDGPADASVLVLNGDILSGV 115

Query: 115 GFSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPK---SNWAVT 171
             +  L   A R    T+   +V DP  FG+V  D + R +S  EKPK  +   ++    
Sbjct: 116 DLNALLERHAEREAEVTLHLTRVPDPRAFGLVPTDGSGRVLSFLEKPKTAEECVTDKINA 175

Query: 172 GLYFYDSKVVE 182
           G Y +   V++
Sbjct: 176 GCYVFRRSVLD 186


>UniRef50_Q5YYW7 Putative UTP-glucose-1-phosphate uridylyltransferase n=1
           Tax=Nocardia farcinica RepID=Q5YYW7_NOCFA
          Length = 298

 Score = 68.9 bits (167), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 70/265 (26%), Positives = 116/265 (43%), Gaps = 45/265 (16%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITT------- 54
           K +I A G G+RL P+T+ + K++LP+ DKP+I + +  L+ +GI +I I+ +       
Sbjct: 9   KAVIPAAGIGSRLLPLTKAIPKEMLPVGDKPVIEHTVRELVASGITDITIVVSGGKSLIQ 68

Query: 55  ---PEDKGYFQRLLGDG--------------SEFGIQLEYAEQPSPDGLAQAFIIGETFL 97
                +     +L  DG              S  G  + Y +Q  P G     +     +
Sbjct: 69  DHFRPNPALVAQLRADGKTAFADAVEEVGELSRLG-HITYLDQHGPYGNGTPVLNAARTM 127

Query: 98  NGEPSCLVLGDNIFFGQGFSPKLRHV--AARTEGATVFGYQVMDP---ERFGV-VEFDDN 151
             EP  ++  D++F  +  +P+ + +  A    GA V     MDP   +R+GV V  DD+
Sbjct: 128 GDEPMLVLWPDDVFVAE--TPRAQQLIEAYERTGAPVLALMPMDPAESQRYGVPVVADDH 185

Query: 152 ----FRAISLEEKPK--QPKSNWAVTGLYFYDSKVVEYAKQVKPS----ERGELEITSIN 201
                R   L EKPK     S++A  G Y     ++E  ++   +      GE+ +T   
Sbjct: 186 GEGLLRITGLREKPKPEDAPSSYAAIGGYVVTPGIIEELRRQTAAWYEHRTGEVYLTDAI 245

Query: 202 QMYLEAGNLTVELLGRGFAWLDTGT 226
            ++  A N     + RG  W DTG 
Sbjct: 246 NVH-AADNPVFGQVIRG-RWYDTGN 268


>UniRef50_Q26CD7 Putative nucleoside diphosphate sugar pyrophosphorylase n=1
           Tax=Flavobacteria bacterium BBFL7 RepID=Q26CD7_9BACT
          Length = 347

 Score = 68.6 bits (166), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 67/243 (27%), Positives = 113/243 (46%), Gaps = 22/243 (9%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITT---PED 57
           ++ +I+AGG G RL P+T  + K +LP+ DKP+I + +  L+  GI++I I       + 
Sbjct: 119 LECMIMAGGRGKRLSPLTDSIPKPMLPLGDKPIIEHNIDRLISFGIQKIYISVKYLGEQL 178

Query: 58  KGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
           + YF    GDGS  GIQ+EY  +  P G A A  + + F       L++  ++F    F 
Sbjct: 179 EAYF----GDGSSKGIQIEYIWEDEPLGTAGALKLVDKF--NTDYVLLMNSDLFTSVNFE 232

Query: 118 PKLRHVAARTEGATVFG--YQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYF 175
                +        V    Y+V  P  + V E D N +  + +EKP     + A  G+Y 
Sbjct: 233 EMYLQLLQENADMVVASTEYKVDVP--YAVFETDGN-KVKAFKEKPSYIYQSNA--GIYI 287

Query: 176 YDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAST 235
               +++   Q+  +E    +IT + +  ++ G   V     GF W+D G      +A  
Sbjct: 288 LKRSLID---QMTKNEY--CDITDVMEKLVQDGGKLVYDPILGF-WIDIGKPSDYKQAQE 341

Query: 236 FVQ 238
           F++
Sbjct: 342 FIK 344


>UniRef50_B0VGT1 Putative Mannose-1-phosphate guanylyltransferase n=1 Tax=Candidatus
           Cloacamonas acidaminovorans RepID=B0VGT1_9BACT
          Length = 231

 Score = 68.6 bits (166), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 49/181 (27%), Positives = 89/181 (49%), Gaps = 5/181 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +IL+GG G+RL P T  + K LLPI +K ++   +  L   G   I + T  + + Y
Sbjct: 1   MKAVILSGGLGSRLKPFTEVIPKPLLPIGEKAVLEIQIEHLKNNGFDHIFLATNYKSE-Y 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   G+GS++G++L  +++  P G A    + +  LN EP  LV+  +I     +    
Sbjct: 60  IENFFGNGSKYGVKLSISKEEKPLGTAGPVKLLQNQLNNEP-FLVMNGDILTLLPYRKLY 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
               ++    T+    +  P +FG +  + +F    +EEKP    +  A  G+Y +  ++
Sbjct: 119 EFACSKETLLTIATKDIYTPFQFGNIHTEGDF-VTGIEEKPNIKTTILA--GIYIFKPEI 175

Query: 181 V 181
           +
Sbjct: 176 L 176


>UniRef50_Q1AW30 Nucleotidyl transferase n=1 Tax=Rubrobacter xylanophilus DSM 9941
           RepID=Q1AW30_RUBXD
          Length = 833

 Score = 68.6 bits (166), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 68/248 (27%), Positives = 117/248 (47%), Gaps = 23/248 (9%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILI---ITTPED 57
           MK +I+AGG GTRL P+T    K ++ I + P + + +++L   G  +I +       E 
Sbjct: 1   MKAVIMAGGQGTRLRPLTSEQPKPMIRIANVPCMEHIVNLLKRHGFTDIAVTLQFMPDEI 60

Query: 58  KGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGET--FLNGEPSCLVLGD---NIFF 112
           + YF    GDGS++G+ + Y+ + SP G A +  + E    L GE   ++ GD   ++  
Sbjct: 61  RDYF----GDGSDWGVNIRYSVEDSPAGTAGSVKMAERQLGLEGERLLIISGDALTDVDL 116

Query: 113 GQGFSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAV 170
           G+     L +   +   AT+    V +P  FG+V   ++ R     EKP   Q  S+   
Sbjct: 117 GE----LLAYHEQKGGEATMVLKSVENPLDFGIVITGEDGRISRFLEKPAWGQVFSDTVN 172

Query: 171 TGLYFYDSKVVEYAKQVKPSERGELEIT-SINQMYLEAGNLTVELLGRGFAWLDTGTHDS 229
           TG+Y  +  V+   +++   E GE + +  +    LE G     ++   + W D GT + 
Sbjct: 173 TGIYLLEPSVL---REIPDPEEGEYDFSKDLFPRLLEQGRPLYGMVTDAY-WEDIGTLEQ 228

Query: 230 LIEASTFV 237
              A+  V
Sbjct: 229 YASANRDV 236


>UniRef50_A3DNE2 Nucleotidyl transferase n=8 Tax=Thermoprotei RepID=A3DNE2_STAMF
          Length = 233

 Score = 68.6 bits (166), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 61/237 (25%), Positives = 100/237 (42%), Gaps = 11/237 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M  +ILAGG G RL P T  + K L+ + +KP++ + +  L   G  E +++     +  
Sbjct: 1   MMAVILAGGFGKRLRPYTEEIPKPLVSVAEKPILEWQIEWLKQYGFNEFVLLVGYRKEKI 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  +G G + G+++ Y  +  P G   A    E  L+ E   LVL  +I          
Sbjct: 61  IEH-IGSGGKLGVKVTYVVEDEPLGTGGAIKNAEHILSKEEKFLVLNGDILTNLNPMKLF 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
             +    E   V    +  P  +GV+E  D+ +     EKPK  +  W   G+Y      
Sbjct: 120 EKLDEHPEFVAVIA-SIPLPSPYGVLEIKDS-KVTGFVEKPKL-QDYWINAGIYAMKPSA 176

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
           ++Y       ERG+LE T+   M  +     V+    G  W    T+  L EA+  +
Sbjct: 177 LKYF-----PERGDLERTAFPAMAKDGVLGAVKY--TGVFWKSVDTYKDLEEATKAI 226


>UniRef50_Q036S8 Glucose-1-phosphate adenylyltransferase n=9 Tax=Lactobacillus
           RepID=GLGC_LACC3
          Length = 380

 Score = 68.2 bits (165), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 73/254 (28%), Positives = 115/254 (45%), Gaps = 23/254 (9%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDK-PMIYYPLSVLMLAGIREILIITTPEDKG 59
           M G+ILAGG GTRL  +T+  +K  +P   +  +I + LS L  +G+    +IT  +   
Sbjct: 5   MLGMILAGGQGTRLGKLTKTTAKPSVPFGGRYRIIDFTLSNLANSGVNTAGVITQYQPL- 63

Query: 60  YFQRLLGDGSEFGIQLEYAE----QPSP--------DGLAQAFIIGETFLNG-EPSCLVL 106
              R + +G+ +G+    A     QP          +G A A      +++   P  L++
Sbjct: 64  ELNRHIQNGASWGLNERGAGVTILQPYASSEGEKFFEGTAHAIYQNIAYIDSYNPQYLLI 123

Query: 107 --GDNIFFGQGFSPKLRHVAARTEGATVFGYQVMDPE--RFGVVEFDDNFRAISLEEKPK 162
             GD+I+    +   L +  A+    TV    V   E  RFG++  DD  R I  EEKP 
Sbjct: 124 LSGDHIY-KMDYQAMLDYHKAKKASLTVAVMPVEKEEAKRFGIMNTDDTDRIIEFEEKPA 182

Query: 163 QPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEI--TSINQMYLEAGNLTVELLGRGFA 220
           +PKSN A  G+Y ++   ++       +  G +E     +   YL     +     RG+ 
Sbjct: 183 KPKSNLASMGIYIFNWPTLKQYLTESYATDGAMEDFGHDVIPAYLTHNEASYAYAFRGY- 241

Query: 221 WLDTGTHDSLIEAS 234
           W D GT  SL EA+
Sbjct: 242 WKDVGTIQSLWEAN 255


>UniRef50_A1RUM7 UDP-glucose pyrophosphorylase n=1 Tax=Pyrobaculum islandicum DSM
           4184 RepID=A1RUM7_PYRIL
          Length = 272

 Score = 68.2 bits (165), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 71/276 (25%), Positives = 122/276 (44%), Gaps = 40/276 (14%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIY--------DKPMIYYPLSVLMLAGIREILII 52
           M+ ++ A G GTRL P ++ V K++ P++         KP++      L  AG+RE   +
Sbjct: 1   MQAVVAAAGLGTRLLPASKEVPKEMFPVFVWEGGSLLVKPVLQVVFEQLFDAGVREFCFV 60

Query: 53  T-----------TPEDKG---YFQR-----LLGDGSEFGIQLE-----YAEQPSPDGLAQ 88
                       TP D G   Y +R       G  + F  ++E     Y  QP P G   
Sbjct: 61  VGRGKRAVEDYFTP-DWGLVEYLERAGKAEAAGALARFYERVEASAIFYVNQPKPLGFGH 119

Query: 89  AFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQVMDPERFGVVEF 148
           A +  E F++G+   +V   + F   G +P    V++      V   +V DP ++GV   
Sbjct: 120 AVLTAEPFIHGD--FVVAAGDTFLMDG-APLAALVSSPPMAIMV--KEVEDPRQYGVAV- 173

Query: 149 DDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAG 208
            +  R + + EKP+ P S  A+   Y   S    Y ++V+P   GE+++T   Q+ +E G
Sbjct: 174 VEGGRVVRVVEKPRDPPSRLAILPFYKLPSDFFRYLRRVRPGVGGEIQLTDAIQLAIEEG 233

Query: 209 NLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEKRQ 244
            +    +  G  ++D GT  + ++A      V ++ 
Sbjct: 234 -VEARPVFYGGEYVDVGTPQTYLKALELALHVARKN 268


>UniRef50_B4U0Q7 UTP--glucose-1-phosphate uridylyltransferase HasC.2 n=24
           Tax=Bacteria RepID=B4U0Q7_STREM
          Length = 322

 Score = 68.2 bits (165), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 67/255 (26%), Positives = 107/255 (41%), Gaps = 45/255 (17%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIIT-----TPE 56
           K II A G GTR  P T+ ++K++LPI DKP I + +   + AGI EIL++T     + E
Sbjct: 26  KAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEEALKAGIEEILVVTGKAKRSIE 85

Query: 57  D--------------KGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPS 102
           D              KG  + L        I L +  Q  P GL  A +  + F+  EP 
Sbjct: 86  DHFDSNFELEYNLQAKGKTELLKLVDETTAINLHFIRQSHPRGLGDAVLQAKAFVGNEPF 145

Query: 103 CLVLGDNIFFGQGFSPK-----------LRHVAA----RTEGATVFGYQVMDPERFGVVE 147
            ++LGD++      S K             H +     R     V  Y V+ P+   V  
Sbjct: 146 VVMLGDDLMDITNPSAKPLTKQLIEDYDCTHASTIAVMRVPHEEVSNYGVIAPQGKAVKG 205

Query: 148 FDDNFRAISLEEKPK--QPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEIT-SINQMY 204
               +   +  EKP   +  S+ A+ G Y    ++    ++  P    E+++T +I+++ 
Sbjct: 206 L---YSVETFVEKPSPDEAPSDLAIIGRYLLTPEIFAILEKQAPGAGNEVQLTDAIDKL- 261

Query: 205 LEAGNLTVELLGRGF 219
               N T  +  R F
Sbjct: 262 ----NKTQRVFAREF 272


>UniRef50_Q67QD8 Putative mannose-1-phosphate guanyltransferase n=1
           Tax=Symbiobacterium thermophilum RepID=Q67QD8_SYMTH
          Length = 343

 Score = 68.2 bits (165), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 64/239 (26%), Positives = 104/239 (43%), Gaps = 20/239 (8%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDK-- 58
           ++ I+LAGG GTRLHP+T  + K ++P+  KP +   +  L   G+ +I +      +  
Sbjct: 3   VRAILLAGGLGTRLHPLTVELPKPMVPVLGKPWLSRLIDQLAAFGVTDITLSLRHGGQVV 62

Query: 59  -GYFQRLLGDGSEFGIQLEYAEQPSPDGLAQA--FIIGETFLNGEPSCLVLGDNIFFGQG 115
             YF+      S  G++L +A +P P G   A  F  G    +   + L+L  +I     
Sbjct: 63  TDYFRE-----SPPGVRLRFAVEPQPLGTGGAIRFAAGPDPTD---TLLILNADIVQTFD 114

Query: 116 FSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGL 173
            +  L          T+   +V DP  +G VE D N R     EKP+  +  S     G+
Sbjct: 115 LNALLEFHRQHRAQVTIGLVEVADPSAYGAVELDKNSRVTRFVEKPRPGETDSRMVNAGV 174

Query: 174 YFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIE 232
           Y +D  V+ +   + P     +E  +   + L  G      L  G+ W D GT D  ++
Sbjct: 175 YVFDPGVLSW---IPPERPVSVERETFPAL-LRDGVRVYGCLCTGY-WKDIGTGDRYLQ 228


>UniRef50_A9B2A2 Nucleotidyl transferase n=1 Tax=Herpetosiphon aurantiacus ATCC
           23779 RepID=A9B2A2_HERA2
          Length = 326

 Score = 68.2 bits (165), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 57/184 (30%), Positives = 88/184 (47%), Gaps = 11/184 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +IL GG GTRL P+T  + K L+PI  + ++   L  L   G+R + I+        
Sbjct: 1   MRAVILVGGLGTRLRPLTNQLPKPLVPIAGEALMSRTLRRLYKQGVRHV-ILAVQYLAEQ 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQA--FIIGET-FLNGEPSCLVLGDNIFFGQGFS 117
           F    GDG+ FG+ L+  ++P   G A A  + + +T  L   P  ++ GD +     F 
Sbjct: 60  FLAAYGDGAAFGLDLQIVQEPEALGTAGAVRYALDQTNLLKAGPILVLNGDEL---TDFD 116

Query: 118 -PKLRHVAARTEG-ATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQ--PKSNWAVTGL 173
             +L     +  G AT+   QV D   FGVV  D N R  + +EKP      +N   +G 
Sbjct: 117 VAQLWQAHGQFGGVATIAVRQVADTSAFGVVASDANQRVYAFQEKPAAGTALANTINSGA 176

Query: 174 YFYD 177
           Y ++
Sbjct: 177 YVFE 180


>UniRef50_Q8YRP4 Mannose-1-phosphate guanyltransferase n=11 Tax=Bacteria
           RepID=Q8YRP4_ANASP
          Length = 389

 Score = 67.8 bits (164), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 54/203 (26%), Positives = 98/203 (48%), Gaps = 26/203 (12%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITT---PED 57
           MK +ILA G GTR+ PIT  + K ++PI  KP++ + L +L   G  +I++  +    E 
Sbjct: 1   MKAMILAAGKGTRVRPITYTIPKPMIPILQKPVMEFLLELLRQHGFDQIMVNVSHLAEEI 60

Query: 58  KGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNG-------------EPSCL 104
           + YF+    DG  FG+Q+ Y+ +   D   +  ++GE   +              + + +
Sbjct: 61  ENYFR----DGQRFGVQIAYSFEGKIDD--EGKLVGEAIGSAGGMRRIQDFSPFFDDTFV 114

Query: 105 VLGDNIFFGQGFSPKLRHVAARTEGATVFGYQVMDPE--RFGVVEFDDNFRAISLEEKP- 161
           VL  +       +  ++   ++   AT+    V + E   +GVV  D+N R  + +EKP 
Sbjct: 115 VLCGDALIDLDLTAAVKWHKSKGSIATIITKTVPEEEVSSYGVVVTDENSRVKAFQEKPS 174

Query: 162 -KQPKSNWAVTGLYFYDSKVVEY 183
            ++  S    TG+Y ++ +V  Y
Sbjct: 175 IEEALSTNINTGIYIFEPEVFNY 197


>UniRef50_Q2WB86 Nucleoside-diphosphate-sugar pyrophosphorylase n=7 Tax=Bacteria
           RepID=Q2WB86_MAGSA
          Length = 349

 Score = 67.8 bits (164), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 66/237 (27%), Positives = 102/237 (43%), Gaps = 24/237 (10%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQR 63
           +++AGG G RL P+T+ V K LLP+  +P++   L   + AG R   I      +   + 
Sbjct: 123 VLMAGGEGRRLRPLTQDVPKPLLPVGPRPILETILKNFIEAGFRNFFISVNYRAE-QVES 181

Query: 64  LLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPS--CLVLGDNIF----FGQGFS 117
             GDGS  G+ + Y  +    G A A       L G PS   +V+  +I     F Q  +
Sbjct: 182 HFGDGSALGVSIRYLREDRQLGTAGAL----GLLPGTPSEPLIVMNGDILTTVDFKQLLA 237

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYD 177
               H AA T     + ++V     +GVVE +   R   +EEKP     N+   G+Y  +
Sbjct: 238 FHQEHRAAATMAVREYHFEV----PYGVVEVEGT-RLKGIEEKPV--VRNFVNAGIYVLN 290

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
            +V+   K  +P       +  I Q  ++ G        R + WLD G  D    A+
Sbjct: 291 PEVLNLVKPGQPH-----NMPQIYQTLMDGGQDCAVFPIREY-WLDIGRLDDFDRAN 341


>UniRef50_A9A5M8 Nucleotidyl transferase n=2 Tax=Thaumarchaeota RepID=A9A5M8_NITMS
          Length = 222

 Score = 67.8 bits (164), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 60/246 (24%), Positives = 116/246 (47%), Gaps = 28/246 (11%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK IILAGG G RL P+T  V K L+PI + P+I + +  L   GI+E++I T     GY
Sbjct: 1   MKAIILAGGRGKRLKPVTDYVPKPLVPIKNIPIIEWQIRYLKKFGIKEVIICT-----GY 55

Query: 61  FQRLLGDG---SEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
              ++ +     + GI+++++ + +P G   A       +N +   ++ GD I      +
Sbjct: 56  KTEMIENHLNMKDIGIKIKFSIEKTPLGTGGAIKKAGKMINEKSFFVLNGDTI-----TN 110

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYD 177
             L+ +  +         +     ++G++E DD+ + ++  EK K+    W   G+Y  +
Sbjct: 111 IDLKKLQKKKNAIAAIELRT----KYGILETDDD-KILNFREK-KEISDTWMNAGIYHLE 164

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNL-TVELLGRGFAWLDTGTHDSLIEASTF 236
             V++        ++G++E T   + Y + G L TV+   +   W    +   + E +  
Sbjct: 165 KTVLKEL-----PDKGDIEKTVFPK-YAKKGTLNTVKF--KNTKWYSVDSFKDMEECALE 216

Query: 237 VQTVEK 242
           ++ + K
Sbjct: 217 IEKIIK 222


>UniRef50_Q9HJ96 Glucose-1-phosphate thymidylyltransferase related protein n=2
           Tax=Thermoplasma RepID=Q9HJ96_THEAC
          Length = 247

 Score = 67.8 bits (164), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 62/254 (24%), Positives = 108/254 (42%), Gaps = 27/254 (10%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYD--------KPMIYYPLSVLMLAGIREILII 52
           M G+I A G GTR    ++   K++  +YD        +PM+   +  +  AGI  I ++
Sbjct: 1   MDGLITAAGLGTRSMA-SKYYRKEIFSVYDERDGQMVIRPMLDAVIYRMKYAGIDNIYVV 59

Query: 53  TTPEDKGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFF 112
              ED G  ++ +    E    L   EQ    G   A  +    ++  P  L  GD +  
Sbjct: 60  LDHED-GVTKKFI---EESYPDLHIIEQRERRGYGYAVYLARDHMDS-PFVLNAGDGMLL 114

Query: 113 GQGFSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTG 172
                  + H  +   G  +  +QV DP ++GV+E   + + + + EKP++P SN A+  
Sbjct: 115 DPDVENTIVH--SFKGGNLLVAFQVDDPRKYGVLEMSGD-KVVGVREKPEKPPSNLALAA 171

Query: 173 LYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIE 232
            Y  D  + ++       +R E E+T      ++AG  T   + R   W+  G      +
Sbjct: 172 FYVLDPSIFDHID----IDRKESELTPAIDATIKAGVKTEARMIRKDEWISVG------Q 221

Query: 233 ASTFVQTVEKRQGF 246
            S++V  V +   F
Sbjct: 222 VSSYVDVVNRTYSF 235


>UniRef50_C6X012 Glucose-1-phosphate thymidylyltransferase n=17 Tax=Bacteroidetes
           RepID=C6X012_FLAB3
          Length = 339

 Score = 67.4 bits (163), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 65/250 (26%), Positives = 104/250 (41%), Gaps = 18/250 (7%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPL-SVLMLAG--IREILIITTPED 57
           MK I+   G G+RL P T  V K L+PI  KP++   +  +  +AG  I EI  I     
Sbjct: 1   MKIIVPMAGRGSRLRPHTLTVPKPLIPIAGKPIVQRLVEDIAKVAGEKIDEIAFIIGDFG 60

Query: 58  KGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
                 L+      G +     Q  P G A A    E  + G+   +   D +F      
Sbjct: 61  SEVEASLIQIAESLGAKGTVYTQDEPLGTAHAIKCAENSMQGD-VVVAFADTLF------ 113

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYD 177
            K   +  +     ++  +V DP  FGVV+ DD        EKP    S+ A+ G+Y+++
Sbjct: 114 -KADFILDKNSDGVIWVKKVDDPSAFGVVKLDDYGFITDFVEKPATFVSDLAIIGIYYFN 172

Query: 178 S-----KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIE 232
           S       + Y       + GE ++T+  +   + G      LG+   W+D G  ++ +E
Sbjct: 173 SAEKLMDEINYIMSNDIKQGGEYQLTTALENLRQKG--AKFSLGKVDDWMDCGNKNATVE 230

Query: 233 ASTFVQTVEK 242
            +  V   EK
Sbjct: 231 TNGKVLNYEK 240


>UniRef50_Q3SPZ3 Nucleotidyl transferase n=1 Tax=Nitrobacter winogradskyi Nb-255
           RepID=Q3SPZ3_NITWN
          Length = 346

 Score = 67.4 bits (163), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 65/241 (26%), Positives = 118/241 (48%), Gaps = 20/241 (8%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQR 63
           +++AGG G+RL P+T  + K L+ + +KP++   L+  + +G  +  I    + +   + 
Sbjct: 120 VLMAGGLGSRLRPLTDDLPKPLIKVGNKPILETVLNGFIKSGFGKFFISVNYKAE-MIRE 178

Query: 64  LLGDGSEFGIQLEYAEQPSPDGLAQAF-IIGETFLNGEPSCLVLGD---NIFFGQGFSPK 119
             GDGS +G++++Y  +    G A A  +I E      P  ++ GD    + F Q     
Sbjct: 179 YFGDGSAWGVEIDYLVESDRLGTAGALSLIPER--PTRPFFVMNGDLLTTVNFEQMLKYH 236

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSK 179
           L H A  T    V  + +  P  FGVV+F+D+ R + + EKP Q    +   G+Y  D +
Sbjct: 237 LEHQAFTT--ICVREHAITVP--FGVVDFEDH-RILGIREKPTQ--KFFVNAGVYLLDPE 289

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           V++Y    +      +++ ++ +  +E G  +V    R + W+D G  D L +AS   Q 
Sbjct: 290 VLDYIGATE-----AVDMPTLIERTIERGKRSVAFPLREY-WIDVGRLDDLQKASDEFQR 343

Query: 240 V 240
           +
Sbjct: 344 I 344


>UniRef50_Q6A5G9 Glucose-1-phosphate thymidylyltransferase n=2 Tax=Propionibacterium
           acnes RepID=Q6A5G9_PROAC
          Length = 278

 Score = 67.4 bits (163), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 65/237 (27%), Positives = 102/237 (43%), Gaps = 36/237 (15%)

Query: 2   KGIILAGGSGTRLHPITRGVS-------------KQLLPIYDKPMIYYPLSVLMLAGIRE 48
           K +I+A G GTR+     GVS             K ++ + D+P + Y +S L  AG  E
Sbjct: 13  KVVIMARGLGTRMRKSVEGVSLTADQAAAASAGVKAMISLDDRPFLDYVISALADAGFDE 72

Query: 49  ILIITTPED---KGYFQRLLGDGSEFG-IQLEYAEQPSPDGLAQAFIIGETFLNGEPSCL 104
             ++  PE    + Y+     D  E   + + YA Q  P G A A    E F  G+   L
Sbjct: 73  FCLVIGPEHNVIRDYY-----DACEKSRLSIVYAVQEHPLGTADAVAAAEEFA-GDDRVL 126

Query: 105 VLGDNIFFGQGFSPKLRHVAAR-TEGAT---VFGYQVMDPER---FGVVEFDDNFRAISL 157
           V+  + F+ +    +LR V A  T G T   +     +DPER   F +++ DD+ +   +
Sbjct: 127 VVNSDNFYPEDAVARLREVPASGTLGFTKRAMIAQSNIDPERIRAFALLDSDDSGQLTDI 186

Query: 158 EEKPKQPKSNWA------VTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAG 208
            EKP     + A          +    ++ E  + +  SERGE EI    +  +E G
Sbjct: 187 IEKPDPHIVDAAGETALVSMNCFLLTPRIFEACRSIDKSERGEYEIVDAVRWMVEHG 243


>UniRef50_Q4UEZ4 GDP-mannose pyrophosphorylase, putative n=2 Tax=Theileria
           RepID=Q4UEZ4_THEAN
          Length = 389

 Score = 67.4 bits (163), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 46/186 (24%), Positives = 85/186 (45%), Gaps = 4/186 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +ILAGG GTR+ P+T  V K L+   ++P+I + +     AG   ++I  T E    
Sbjct: 1   MKSVILAGGYGTRIRPLTLSVPKPLVDFCNRPVIEHQIQACKNAGFDHVIIAVT-EHHNI 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFL---NGEPSCLVLGDNIFFGQGFS 117
            + +     ++ I+++++ + +P G A    + +  +   +     +V   +I       
Sbjct: 60  TEPIKNLAEKYSIRIDFSTESTPLGTAGPLRLAKDLICSDDDSDDFVVFNSDIICNYPLK 119

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYD 177
             L     ++   T+    V +   FGV+  D+N    S  EKPK   SN    G+Y   
Sbjct: 120 ELLESHRKKSAKVTIMVTTVENSSEFGVILHDENGLIKSFLEKPKNATSNTINAGVYVLS 179

Query: 178 SKVVEY 183
            +V+++
Sbjct: 180 KEVLDH 185


>UniRef50_C7PZ89 Nucleotidyl transferase n=3 Tax=Actinomycetales RepID=C7PZ89_CATAD
          Length = 318

 Score = 67.4 bits (163), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 65/265 (24%), Positives = 117/265 (44%), Gaps = 45/265 (16%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITT------- 54
           + +I A G G+RL P+T+ + K++LP+ D+P+I + +  L+ +GI +I I+ +       
Sbjct: 7   RAVIPAAGIGSRLLPLTKAIPKEMLPVGDRPVIEHTVRELVASGITDITIVVSGGKDLIQ 66

Query: 55  --------------PEDKGYFQRLLGDGSEFGI--QLEYAEQPSPDGLAQAFIIGETFLN 98
                          E+K  + + + D  E      + Y +Q  P G     +       
Sbjct: 67  QHFRPNPALIDQLHAENKHAYAKAVADVVELARAGHITYLDQQGPYGNGTPVLNASRGSG 126

Query: 99  GEPSCLVLGDNIFFGQGFSPKLRHVAARTE--GATVFGYQVMDPE---RFGVVEFDDN-- 151
            EP  ++  D++F  +   P+ + + A  E  G  V     MD E   R+GV E +++  
Sbjct: 127 DEPMLVLWPDDVFVAK--VPRAQQLIAAYEKTGCPVLALMPMDRENSRRYGVPEVNEDLG 184

Query: 152 ---FRAISLEEKPK--QPKSNWAVTGLYFYDSKVVEYAKQV----KPSERGELEIT-SIN 201
               R  SL EKP+     S++A  G Y   + ++E  + +    +  + GE+ +T +IN
Sbjct: 185 DGLLRISSLVEKPEPGSAPSDFAAIGGYVVTAAIIEELEAITRRWEQHQTGEIYLTDAIN 244

Query: 202 QMYLEAGNLTVELLGRGFAWLDTGT 226
               +       + GR   W DTG 
Sbjct: 245 TYAAKRAVYGQVIAGR---WYDTGN 266


>UniRef50_B8I5R7 Nucleotidyl transferase n=1 Tax=Clostridium cellulolyticum H10
           RepID=B8I5R7_CLOCE
          Length = 810

 Score = 67.4 bits (163), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 56/196 (28%), Positives = 98/196 (50%), Gaps = 11/196 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIRE--ILIITTPE-D 57
           MK II+AGG G+RL P+T  + K ++PI +KP++ + + +L   GI +  I ++  P+  
Sbjct: 1   MKAIIMAGGEGSRLRPLTCDLPKPMVPIMNKPVLEHTIGLLKSYGITDIGITLLYHPQII 60

Query: 58  KGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
           K YF    G G   G+ + Y  + SP G A        FL+ E   ++ GD++       
Sbjct: 61  KDYF----GSGHSCGVNIYYFLEESPLGTAGGIKNAREFLD-ETFIVISGDSL-TDLNIE 114

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYF 175
             L +  ++   AT+   +V  P  +GVV  D++       EKP   +  S+   TG+Y 
Sbjct: 115 NALEYHRSKKSIATLILTKVDVPLEYGVVLTDEDGSIKGFVEKPSWGEIFSDMVNTGIYI 174

Query: 176 YDSKVVEYAKQVKPSE 191
            + +++ Y +  K ++
Sbjct: 175 LEPEILSYIEVGKNTD 190


>UniRef50_B5YF33 Mannose-1-phosphate guanyltransferase n=2 Tax=Dictyoglomus
           RepID=B5YF33_DICT6
          Length = 827

 Score = 67.4 bits (163), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 76/284 (26%), Positives = 129/284 (45%), Gaps = 28/284 (9%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREI--LIITTPEDK 58
           M+ +I+AGG GTRL P+T    K +  I  KP++ + +++L   G RE+   +   PE  
Sbjct: 1   MRAVIMAGGEGTRLRPLTLTRPKPMTYIVGKPIMEHIINLLSEQGFRELTATLYYLPE-- 58

Query: 59  GYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSP 118
              Q    DGS + + L+Y+ + SP G A +    +  L  +P   +L   I  G   + 
Sbjct: 59  -IIQEYFDDGSNWNVNLDYSIEESPLGTAGSV---KYALKNKPKDRIL---IISGDALTD 111

Query: 119 -KLRHVAARTE--GA--TVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVT 171
             LR      E  GA  T+    V +P  +GVV   ++ + I   EKP   +  S+   T
Sbjct: 112 FNLREAIKFHEENGALVTIVLTSVENPLEYGVVITKEDGKIIKFLEKPSWGEVFSDSVNT 171

Query: 172 GLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLI 231
           G+Y  + +V++Y    +P +  +     +  M LE        L +G+ W D G  +  +
Sbjct: 172 GIYILEPEVLDYIPDNQPFDFSK----DLFPMLLEKNAPLYGYLAQGY-WCDIGNLEQFL 226

Query: 232 EASTFVQTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAK 275
           +A+     + K+   KI   E +    G   +E V+ A S+  +
Sbjct: 227 QAN--FDALNKKVKIKIPGREILP---GIYTNEEVEIATSAFIR 265


>UniRef50_C7H386 UTP-glucose-1-phosphate uridylyltransferase n=2
           Tax=Faecalibacterium prausnitzii RepID=C7H386_9FIRM
          Length = 298

 Score = 67.4 bits (163), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 72/267 (26%), Positives = 112/267 (41%), Gaps = 42/267 (15%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILII-----TTPE 56
           K +I A G GTR+ P T+ + K +LPI DKP I Y +   + +GI +ILII     +  E
Sbjct: 13  KAVIPAAGLGTRVLPATKAMPKGMLPIVDKPAIQYLVEEAVKSGITDILIILGRNQSIIE 72

Query: 57  DKGYFQR-------LLGDGSE------FGI----QLEYAEQPSPDGLAQAFIIGETFLNG 99
           D  +F R       L   G E       GI     + +  Q    GL  A  + + F   
Sbjct: 73  D--HFDRSPELEEKLAAPGKEKMLEECLGISNLANIFFVRQKQTLGLGHAVSMAKAFTGD 130

Query: 100 EPSCLVLGDNIFFGQGFSPKLRHVAARTE-----GATVFGYQVMDPERFGVVE----FDD 150
           +P  ++ GD++ +G+   P    +    E      A V      D  R+  ++     D+
Sbjct: 131 DPFVVIYGDDVIWGE--DPVCAQLIRAYEEFGRPAAGVSAVPWADVSRYCSLKTTPIHDN 188

Query: 151 NFRAISLEEKPK--QPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLE-- 206
            F    + EKPK  Q  SN+++ G      ++ +     KP   GE+++T     Y    
Sbjct: 189 YFFVDDMIEKPKKGQEFSNYSILGRVLLTPEIYDILAHTKPGAGGEIQLTDAMAEYARNC 248

Query: 207 AGNLTVELLGRGFAWLDTGTHDSLIEA 233
            G   VE  G  +   D G    ++EA
Sbjct: 249 GGMTAVEFTGTHY---DMGNKLRVVEA 272


>UniRef50_D1C4F4 Nucleotidyl transferase n=1 Tax=Sphaerobacter thermophilus DSM
           20745 RepID=D1C4F4_SPHTD
          Length = 337

 Score = 67.4 bits (163), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 67/248 (27%), Positives = 107/248 (43%), Gaps = 29/248 (11%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M  II   G GTRL P T    K L+ +  KP++ + L  L+   I +++ +T     GY
Sbjct: 1   MNIIIPVAGLGTRLRPQTWSKPKPLVSVAGKPVLGHVLDRLLALPIDKVVFVT-----GY 55

Query: 61  FQRLLGDGSEFGIQLEY------AEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQ 114
               LGD  E  ++  Y       EQ    G + A I     + G P+ +V  D +    
Sbjct: 56  ----LGDQIEDYVRQNYRFDATFVEQKEQLGQSHAIIQARGEVTG-PTLVVFPDML---- 106

Query: 115 GFSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLY 174
            F   L  ++  T    +F  +V DP RFGV+E  +N R   L EKP+   SN A+ G+Y
Sbjct: 107 -FEADLDQISGLTADGALFVKEVDDPRRFGVIEV-ENGRITRLVEKPETMVSNLAIVGIY 164

Query: 175 FYDS-----KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDS 229
           ++ +       ++Y        +GE  +    Q  ++ G     L      W D G   +
Sbjct: 165 YFRAVEDLFDAIDYQMAHNIQTKGEYFLADAIQHMIDQGTHFTYL--PVTVWEDCGNPKA 222

Query: 230 LIEASTFV 237
           L+  + ++
Sbjct: 223 LLNTNRYL 230


>UniRef50_A5IKI2 Glucose-1-phosphate adenylyltransferase, GlgD subunit n=12
           Tax=Thermotogaceae RepID=A5IKI2_THEP1
          Length = 379

 Score = 67.0 bits (162), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 57/199 (28%), Positives = 99/199 (49%), Gaps = 21/199 (10%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDK-PMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           G+ILAGG   RL P+T+  +   +P++ K   I + LS ++ +GIR++ I+T    +   
Sbjct: 14  GLILAGGKSDRLWPLTKVRASAAVPVFGKYRAIDFTLSNMVNSGIRKVGILTQYNPRSLM 73

Query: 62  QRLLGDGSEFGIQLE----YAEQP--SPD------GLAQAFIIGETFLN-GEPSCLVLG- 107
             L G G E+ +  +    +  QP   P+      G A A     T L  GE   +++G 
Sbjct: 74  DHL-GSGKEWDLDRKSGGLFILQPYVGPNREVWYRGTADAIFQNMTILRRGEEDHVLIGS 132

Query: 108 -DNIF---FGQGFSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQ 163
            D+I+   +   F+  L+  A  T        +  +   +G+V+ DD+ R + +EEKP  
Sbjct: 133 GDHIYKMIYRDLFNYHLKKGADITLVVKELD-ETYNLSEYGIVQLDDDMRVVEIEEKPAH 191

Query: 164 PKSNWAVTGLYFYDSKVVE 182
           PK N A  G+YF + ++++
Sbjct: 192 PKGNIAFLGVYFMNKELLK 210


>UniRef50_B3PEF2 Glucose-1-phosphate adenylyltransferase n=1 Tax=Cellvibrio
           japonicus Ueda107 RepID=B3PEF2_CELJU
          Length = 352

 Score = 67.0 bits (162), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 66/255 (25%), Positives = 117/255 (45%), Gaps = 27/255 (10%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKP-MIYYPLSVLMLAGIREILIITTPEDKGYF 61
           GI+LAGG G RL  +TR + K L+P   +  MI + L   + +G++E+++++   +    
Sbjct: 6   GILLAGGKGQRLKQLTRELPKPLVPYAAQCRMIDFSLQNCVDSGVQEVMLLSKHMETLIH 65

Query: 62  QRLLGDGS-----EFGIQLEYAEQPS---------PD--GLAQAFIIGETFL--NGEPSC 103
           Q LL + +      FG       QP+         PD  G A A + G  ++  +G    
Sbjct: 66  QYLLAEWTHKIKIHFGPYQALHHQPAETVYASVQKPDEQGTADALLNGREYICRDGYEDV 125

Query: 104 LVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQVMDPER---FGVVEFDDNFRAISLEEK 160
           L+L  +  +   F  K+  +   ++ A   GYQ +  E    FG+  FD +   +   EK
Sbjct: 126 LILHSDHIYHYDFK-KMYELHQSSKAALTIGYQEIPLEYVKLFGMSRFDTDGNLVEFVEK 184

Query: 161 PKQPKSNWAVTGLYFYDSKVV-EYAKQVKPSE-RGELEITSINQMYLEAGNLTVELLGRG 218
           P  P +N   T +  ++ +++ +Y  Q+K +E R ++    I  M L  G +   +    
Sbjct: 185 PANPTANTVFTAVCIFNIRLMYQYLDQLKHTEWRHDISHDLIPAM-LRNGEIIKGICFED 243

Query: 219 FAWLDTGTHDSLIEA 233
           + W D GT +   +A
Sbjct: 244 Y-WEDIGTTERFYKA 257


>UniRef50_B8LVX3 Mannose-1-phosphate guanylyltransferase n=2 Tax=Leotiomyceta
           RepID=B8LVX3_TALSN
          Length = 741

 Score = 66.6 bits (161), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 68/252 (26%), Positives = 107/252 (42%), Gaps = 19/252 (7%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +  +IL GG GTRL P+T  + K L+   ++PMI + +  L  AG+ +I++         
Sbjct: 378 LSALILVGGFGTRLRPLTLTLPKPLVEFGNRPMILHQVESLAAAGVTDIVLAVNYRPDIM 437

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPS-CLVLGDNIFFGQGFSPK 119
            Q L     ++ I +E++ +  P G A    + E  L  + S   VL  ++     F   
Sbjct: 438 VQALKKYEEQYNINIEFSVESEPLGTAGPLKLAEKILGKDDSPFFVLNSDVICEYPFKQL 497

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNF--RAISLEEKPKQPKSNWAVTGLYFYD 177
                A  +  T+   +V +P ++GVV    N   R     EKP +   N    G+Y  +
Sbjct: 498 AEFHKAHGDEGTIVVTKVDEPSKYGVVVHKPNHPSRIDRFVEKPVEFVGNRINAGIYILN 557

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEA----GNLTVELLGRGFAWLDTG-THDSLIE 232
             V+         +R EL  TSI Q    A    G L    L  GF W+D G   D L  
Sbjct: 558 PSVL---------KRIELRPTSIEQETFPAIVKEGQLHSFDL-EGF-WMDVGQPKDFLSG 606

Query: 233 ASTFVQTVEKRQ 244
              ++ ++ KR 
Sbjct: 607 TCLYLTSLAKRN 618


>UniRef50_C1ABC1 Glucose-1-phosphate thymidylyltransferase n=1 Tax=Gemmatimonas
           aurantiaca T-27 RepID=C1ABC1_GEMAT
          Length = 329

 Score = 66.6 bits (161), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 63/244 (25%), Positives = 110/244 (45%), Gaps = 26/244 (10%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPL-SVLMLAGIREILIITTPEDKG 59
           MK II   G GTRL P T  V K +L +  +P++ Y +  V+ L  + +++ IT     G
Sbjct: 1   MKVIIPLAGKGTRLRPHTHVVPKPMLKVAGRPVMSYVMDDVMRLGNVEQVVYIT-----G 55

Query: 60  YFQRLLG--DGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
           + +  +     + + I   + EQ   DG A A  +   +++ +P  ++  D I     F 
Sbjct: 56  HLKEKVEAFTKANYAIPSVFIEQAVQDGTAGAVALARDYVD-QPVLIIFVDTI-----FD 109

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYD 177
             L           ++  +V D +RFGVV  D       + EKPK+P S  A  GLY+  
Sbjct: 110 ADLSITKDTEADGIIWTKEVEDYQRFGVVVTDAEGHMTRIVEKPKEPISKRANIGLYYIR 169

Query: 178 S-----KVVEYAKQVKPSERGELEITSINQMYLEAGN--LTVELLGRGFAWLDTGTHDSL 230
           +     + + +     P+ +GE  +T   Q  ++ G     V++ G    W D G  ++L
Sbjct: 170 NWKLLYEGIAHVLTTTPN-KGEWYLTDAFQYMIDKGAKIKVVDVDG----WYDAGQLETL 224

Query: 231 IEAS 234
           ++ +
Sbjct: 225 LDTN 228


>UniRef50_Q0AV26 Mannose-1-phosphate guanyltransferase n=1 Tax=Syntrophomonas wolfei
           subsp. wolfei str. Goettingen RepID=Q0AV26_SYNWW
          Length = 343

 Score = 66.6 bits (161), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 51/188 (27%), Positives = 96/188 (51%), Gaps = 11/188 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDK-- 58
           MK +I+A G G+RL P+T+   K ++P+ ++P++   + +L     +E++     + +  
Sbjct: 1   MKAMIMAAGVGSRLMPLTKDTPKPMVPMTNRPLMENIVELLGRHHFKEVIANLHHQGESI 60

Query: 59  -GYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
            GYF     DG +FG++L Y+ +    G A      E FL+   + +V+  +       S
Sbjct: 61  SGYFD----DGHDFGLKLLYSPEEVLLGTAGGVKKCEWFLD--ETFVVISGDALTDMDLS 114

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYF 175
             L     R   AT+   +V + E+FGVV   ++ R    +EKP  ++  S+ A TG+Y 
Sbjct: 115 ELLAQHRKRGALATIALKEVENVEQFGVVLTAEDGRISRFQEKPGREEALSHQANTGIYV 174

Query: 176 YDSKVVEY 183
           ++ ++ +Y
Sbjct: 175 FEPEIFKY 182


>UniRef50_UPI0001C337A3 Nucleoside-diphosphate-sugar pyrophosphorylase family protein n=1
           Tax=cyanobacterium UCYN-A RepID=UPI0001C337A3
          Length = 244

 Score = 66.2 bits (160), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 59/245 (24%), Positives = 113/245 (46%), Gaps = 21/245 (8%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +K +ILAGG GTR+  +   + K +  + +KP I + +S L   GI++ +I T     GY
Sbjct: 4   IKAVILAGGYGTRIKHLISDIPKPMFRVAEKPFIEWIISYLKQQGIKQGIIST-----GY 58

Query: 61  F----QRLLGDGSEFGIQLEYAEQPSPDGLAQAFI--IGETFLNGEPSCLVLGDNIFFGQ 114
                +         GI +   ++ +  G A  FI  + ++ L+ E   ++ GD++    
Sbjct: 59  LGEVIEEYFNQHKISGIDINCYQEKTQLGTAGGFIHAVKQSGLSPEAWLVMNGDSL-IAS 117

Query: 115 GFSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLY 174
                + ++     G  + G  V D  R+G + FDD+   +   E  K+    +   G+Y
Sbjct: 118 NLEKLISYLDIEEVGCVILGMSVNDTSRYGSLIFDDSNNLLRFSE--KENGQGFINGGIY 175

Query: 175 FYDSKVVEYAKQVKP-SERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEA 233
            +  K++EY     P S   ++  T + Q      N+ +++      +LD GT ++L++A
Sbjct: 176 LFRHKILEYFPSKYPLSFEYDIFPTLLQQ------NIKIKVCEVQSPFLDIGTPETLMQA 229

Query: 234 STFVQ 238
             F++
Sbjct: 230 EKFIK 234


>UniRef50_B0K747 Nucleotidyl transferase n=10 Tax=Thermoanaerobacteraceae
           RepID=B0K747_THEP3
          Length = 776

 Score = 66.2 bits (160), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 51/194 (26%), Positives = 93/194 (47%), Gaps = 13/194 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIRE--ILIITTPED- 57
           MKGII+AGG G+RL P+T  + K ++P+ +KP I + +  L   GI++  + +   P+  
Sbjct: 1   MKGIIMAGGEGSRLRPLTADIPKPMVPVANKPAIKHIVEHLHKYGIKDLAVTLFYLPQKI 60

Query: 58  KGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
           K Y +       E+G ++++  +  P G A +      FLN   + +V+  ++       
Sbjct: 61  KKYLE------EEYGDEIKFYIEDKPLGTAGSVKNARDFLND--TFIVMSGDVITDVNIK 112

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYF 175
                   +    T+   +V  P  +GVV  D+  +     EKP   +  S+   TG+Y 
Sbjct: 113 EAYEFHRKKGAKVTLILTRVDVPLEYGVVIVDEEGKIKKFLEKPSWGEVFSDTVNTGIYI 172

Query: 176 YDSKVVEYAKQVKP 189
            + +++E+  Q KP
Sbjct: 173 IEPEILEFIPQDKP 186


>UniRef50_UPI0001C315B1 Nucleotidyl transferase n=1 Tax=Conexibacter woesei DSM 14684
           RepID=UPI0001C315B1
          Length = 329

 Score = 66.2 bits (160), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 53/185 (28%), Positives = 89/185 (48%), Gaps = 10/185 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++LA G GTRL P+T  + K ++P+ D+P++ + + +L   G  EI+      +  Y
Sbjct: 1   MKAMVLAAGLGTRLRPLTYEIPKPMVPVLDRPVMAHIVDLLERHGYGEIV-----ANLHY 55

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F   +   + FG ++ Y E+P   G A        FL  +   ++ GD +          
Sbjct: 56  FPDTI--RAYFGDRIVYREEPELLGTAGGVRNCADFLADDTFLIISGDALTDIDLTRFVK 113

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPK--SNWAVTGLYFYDS 178
           RH  A    AT+   +V D   FGVV  DD  R    +EKP+  +  S+    G+Y ++ 
Sbjct: 114 RHKEAGGV-ATLAVKRVADTREFGVVLHDDTGRITGFQEKPEPAEALSDLGNCGIYLFEP 172

Query: 179 KVVEY 183
           ++ +Y
Sbjct: 173 RIFDY 177


>UniRef50_B4D758 Nucleotidyl transferase n=1 Tax=Chthoniobacter flavus Ellin428
           RepID=B4D758_9BACT
          Length = 251

 Score = 66.2 bits (160), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 63/247 (25%), Positives = 107/247 (43%), Gaps = 17/247 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLM-LAGIREILIITTPEDKG 59
           M  +ILA G  TRL+P+T+  +K LL +  KPM+ + +  L  + GI ++ ++T  +   
Sbjct: 1   MNILILAAGYATRLYPLTQNKAKPLLEVAGKPMMEWVIDNLAPIEGIEKVYVVTNSKFAA 60

Query: 60  YFQRLLGDGSEFGIQLEY-----AEQPSPDGLAQ----AFIIGETFLNGEPSCLVLGDNI 110
            FQ      ++   +L +           D L        +I    L      +V GDN+
Sbjct: 61  DFQAWADHYNQTHAKLAFEIINDGSTSDADKLGAIGDINLVISRAGLASSDLIVVAGDNL 120

Query: 111 FFG--QGFSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNW 168
           F    Q F    +       G    G  + + +++GVV  + +    S EEKP +PKS  
Sbjct: 121 FNQSLQDFGTFCQSKQQPVLGVYDVG-NLTEAKKYGVVAVNGSGEISSFEEKPAEPKSTL 179

Query: 169 AVTGLYFYDSKVV-EYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTH 227
               LY+Y +KVV E+   +      +     +  +Y      T ++ G    W D G+ 
Sbjct: 180 IGIALYYYPAKVVAEFVTYLAAGNNPDQPGRFVQWLYQRTPVQTWQVPG---TWFDVGSK 236

Query: 228 DSLIEAS 234
           ++L EA+
Sbjct: 237 ETLEEAN 243


>UniRef50_A8M9M9 Nucleotidyl transferase n=1 Tax=Caldivirga maquilingensis IC-167
           RepID=A8M9M9_CALMQ
          Length = 263

 Score = 66.2 bits (160), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 61/219 (27%), Positives = 94/219 (42%), Gaps = 20/219 (9%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPI--------YDKPMIYYPLSVLMLAGIREILIITT 54
            ++ A G GTR  P T    K LLP+        + +PM+   ++ L   G  +I I   
Sbjct: 5   AVVTAAGLGTRDGPWTLIFPKALLPLVVKINGITHIRPMLDLIITTLTRVGCSKICITRR 64

Query: 55  PEDKGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQ 114
            +D    +        F +  ++  Q  P G   A   G   LN     +V  D+ F   
Sbjct: 65  SDDDAIVKYTKALWGTFNV--DFTIQDEPRGFGDAVYRGLGCLNNVDWVIVHSDDGFMIN 122

Query: 115 GFS---PKLRHVAARTEGATVFGYQVMDPERFGVV-----EFDDNFRAISLEEKPKQPKS 166
             S     ++  A       VF  +V DP R+GV+     E    +R   +EEKPK PKS
Sbjct: 123 ESSILMNSIKFAADSNIDGLVFVRRVNDPSRYGVLQGFVEEGTGLYRVTEIEEKPKVPKS 182

Query: 167 NWAVTGLYFYD-SKVVEYAKQVKPSERGELEIT-SINQM 203
           N A+T +Y +  S + E  ++++   R  +E T +I QM
Sbjct: 183 NLALTAVYLFKYSILTETLRKIEDEGRPIIEFTDAIKQM 221


>UniRef50_C0A4C2 UTP-glucose-1-phosphate uridylyltransferase n=1 Tax=Opitutaceae
           bacterium TAV2 RepID=C0A4C2_9BACT
          Length = 274

 Score = 65.9 bits (159), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 71/276 (25%), Positives = 109/276 (39%), Gaps = 47/276 (17%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK II A G GTR  PI + V K++LP+ DKP+I+Y ++    AG  EILI+ + + K  
Sbjct: 1   MKAIIPAAGLGTRFLPIAKAVPKEMLPLGDKPVIHYVVAEAAAAGFDEILIVIS-QGKEC 59

Query: 61  FQRLLGDGSEFGIQLE---------------------YAEQPSPDGLAQAFIIGETFL-N 98
            Q       +    LE                     Y  Q    GL  A ++G  F+ N
Sbjct: 60  IQHYFAPNPDLERHLEKIGKLQALEDVRAVSRLARISYTYQKEMRGLGDAVLLGREFVGN 119

Query: 99  GEPSCLVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQVMDPERF-------GVVEFDDN 151
                ++LGD +       P +R    +    +V   +    ER        G +  D  
Sbjct: 120 DSLFAVLLGDTVMHQSSPLPAMRAAWEKWRQPSVC-LERCPAERVSKYGVAGGTLREDGV 178

Query: 152 FRAISLEEKPKQ------------PKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEIT- 198
           F    L EKP              P    A    Y +  ++ ++ +       GE+++T 
Sbjct: 179 FTLDRLVEKPAPDAAPRLRSADGVPLPFHAFAARYLFTPQIFDHLENTHAGFGGEIQLTD 238

Query: 199 SINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
           ++ Q+ L  G L V   G+    LD G    LI+A+
Sbjct: 239 AMEQLRLRDGMLGVTWPGK---RLDIGNPAGLIDAA 271


>UniRef50_A2SRW4 UDP-glucose pyrophosphorylase n=3 Tax=Euryarchaeota
           RepID=A2SRW4_METLZ
          Length = 312

 Score = 65.9 bits (159), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 58/243 (23%), Positives = 104/243 (42%), Gaps = 48/243 (19%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKG-- 59
           K +I A G GTR  PIT+ + K+++P+ DKP+I Y +   + +G  +ILIIT    +   
Sbjct: 29  KAVIPAAGWGTRFFPITKAMPKEMVPVVDKPVIQYVVEEAVASGCDDILIITGKNKRAIE 88

Query: 60  -YFQ---------------RLLGDGSEFG--IQLEYAEQPSPDGLAQAFIIGETFLNGEP 101
            +F                +LL +  +      + +  Q    GL  A +  +  +  EP
Sbjct: 89  DHFDNSQELNEHLRNSGDLKLLAESEKLADLADIHFIRQKEQKGLGDAILCAKQHVGDEP 148

Query: 102 SCLVLGDNIFF----GQGFSPKLRHVAARTEGATVFGYQVMDPER----FGVVEFDDNFR 153
             ++LGD I       +  + +L  +  R +   V G + + PE     +G+++      
Sbjct: 149 FTVLLGDTICIPDAEAKPCTAQLIDIYKRYK-LPVIGVETV-PEHKIKDYGIID------ 200

Query: 154 AISLEEK------------PKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSIN 201
            I LEE+            P++  SN    G Y    ++    +  KP  +GE+++T   
Sbjct: 201 GILLEERLYQIKDIIEKPTPEEAPSNVGAMGRYLLTPEIFAILEDTKPGRKGEIQLTDAL 260

Query: 202 QMY 204
           + Y
Sbjct: 261 RHY 263


>UniRef50_B1L6P6 Nucleotidyl transferase n=1 Tax=Candidatus Korarchaeum cryptofilum
           OPF8 RepID=B1L6P6_KORCO
          Length = 348

 Score = 65.5 bits (158), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 69/249 (27%), Positives = 110/249 (44%), Gaps = 37/249 (14%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK  +LA G G RL P T  + K LLPI    ++ + L++L      E+ ++       Y
Sbjct: 1   MKVALLAAGKGNRLRPATDSIPKPLLPIACSTLLDHNLALL---NSPEVYVVVC-----Y 52

Query: 61  FQRL-LGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGF--- 116
            + L LG  S++G+ L   +Q  P G   A +  E  +  +   L+L  +I+   GF   
Sbjct: 53  MKELFLGYRSKYGVNL--VDQGEPLGTGHAVLKLEDSVKED--LLLLYSDIYIPPGFLEI 108

Query: 117 ----SPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAV 170
                 K  H+ A           V  P  FGV+E + N     + EKP+  +  SN  V
Sbjct: 109 FLSERDKYDHLVAVA--------PVERPWEFGVIEAEGNLLK-RIVEKPRRGEEPSNLVV 159

Query: 171 TGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLG--RGFAWLDTGTHD 228
            G++     + +  + + PS RGE+E+TS     +E G    E +G  R   W+D G  +
Sbjct: 160 AGVFLLSQSIFDILRGLGPSPRGEIELTSAITEAVERG----ERVGIVRMSPWVDAGRRE 215

Query: 229 SLIEASTFV 237
             + A   +
Sbjct: 216 DFLLAQELL 224


>UniRef50_C7DG73 Nucleotidyl transferase n=1 Tax=Candidatus Micrarchaeum acidiphilum
           ARMAN-2 RepID=C7DG73_9EURY
          Length = 266

 Score = 65.5 bits (158), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 55/219 (25%), Positives = 97/219 (44%), Gaps = 21/219 (9%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K +I A G G R +P+TR   K++LPI DKP+I+Y +     +G+ EILII         
Sbjct: 5   KAVIPAAGLGKRFYPLTRSQPKEMLPIVDKPVIHYVVEEAAKSGLDEILIIVGKGKDAII 64

Query: 62  QRLLGDGSEFGIQLEYAEQPSPD----------GLAQAFIIGETFLNGEPSCLVLGDNIF 111
                  +   ++ +Y     P+          GLA A    + F+  +P  ++LGD I+
Sbjct: 65  NYFDKTNTYADLEKDYKIDDFPNIYFIRQKEQLGLADAIRYAKGFVGDDPFVVLLGDTIY 124

Query: 112 FGQG---FSPKLRHVAARTEGATVFGYQVMDP--ERFGVVEFDDNFRAI----SLEEKP- 161
                   + +L  V +     T+   +V     + +G+++ +     +    +L EKP 
Sbjct: 125 KSSSPLTVTQQLIKVYSDHNSPTIAVEEVPKDKIKDYGIIDGNKISNRLWLINNLVEKPQ 184

Query: 162 -KQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITS 199
            +   SN  +TG Y  +S +  Y  ++K     E ++T 
Sbjct: 185 IQNAPSNIGITGAYILESDIFGYIDKIKMGINNEYQLTD 223


>UniRef50_A0LAF2 Nucleotidyl transferase n=1 Tax=Magnetococcus sp. MC-1
           RepID=A0LAF2_MAGSM
          Length = 264

 Score = 65.5 bits (158), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 66/244 (27%), Positives = 102/244 (41%), Gaps = 19/244 (7%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPI-YDKPMI------------YYPLSVLMLAGIREI 49
            I+ A G G+RL P      K+L P+ Y   +I            +Y L  L+ AG++ I
Sbjct: 15  AIVPAAGKGSRLAPFP--CPKELFPVGYQDYLIQGKMEKRPKVVSHYLLDNLIQAGVKRI 72

Query: 50  LIITTPEDKGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDN 109
            +I   +DK       G+GS+FG+ + Y  Q   DG+  A  +   ++  E     + D 
Sbjct: 73  FLIVG-DDKWDIMTYYGNGSDFGVDIAYLFQQRLDGMPSAINLATPWMQDEVVLFGMPDT 131

Query: 110 IFFGQ-GFSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQP--KS 166
           I      FS  L +        T+  +    PE+FG+VE D +   I   +KPKQ   ++
Sbjct: 132 IIEPHDAFSQLLEYHLHEQADLTLGLFATDTPEKFGMVEMDGDNNVIFTVDKPKQSALQT 191

Query: 167 NWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGT 226
            W         S+++    Q  P    EL +  +  + LE G     LL     +LD GT
Sbjct: 192 MWGNACWSPSFSQLLSGYLQANPYLGKELVLGDVFNLALEKGMRVKGLLFAEGRYLDIGT 251

Query: 227 HDSL 230
              L
Sbjct: 252 THEL 255


>UniRef50_B1Y7P5 Nucleotidyl transferase n=1 Tax=Leptothrix cholodnii SP-6
          RepID=B1Y7P5_LEPCP
          Length = 274

 Score = 65.5 bits (158), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 34/81 (41%), Positives = 52/81 (64%), Gaps = 3/81 (3%)

Query: 1  MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITT-PEDKG 59
          ++ I+LA G G R+ P+T    K LLPI+ +PMI + L  L   G++E++I T   ED+ 
Sbjct: 7  LRAIVLAAGRGERMRPLTDTTPKPLLPIFGRPMIEWHLLALARDGVQEVVINTAWLEDQ- 65

Query: 60 YFQRLLGDGSEFGIQLEYAEQ 80
           F  +LGDGS FG++L Y+ +
Sbjct: 66 -FPAVLGDGSRFGLRLRYSTE 85


>UniRef50_B3DZW7 Nucleoside-diphosphate-sugar pyrophosphorylase n=1
           Tax=Methylacidiphilum infernorum V4 RepID=B3DZW7_METI4
          Length = 256

 Score = 65.5 bits (158), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 64/249 (25%), Positives = 107/249 (42%), Gaps = 21/249 (8%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLM-LAGIREILIITTPEDKG 59
           M+ ++L+ G  TRL+P+T    K LLP+  KP++ Y    L+ L  +  I ++T  +   
Sbjct: 10  MRALLLSAGYATRLYPLTLNQPKALLPVAGKPIMDYITDKLLELPALEAIYVVTNHKFYT 69

Query: 60  YF---QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIG------ETFLNGEPSCLVLGDNI 110
           +F   +     G+   + LE  +  S     +   IG      ET   G+   +V  DN+
Sbjct: 70  HFLEWKNRYQQGAVKKLPLEVLDDGSTTENNRLGAIGDMDFAIETKKIGDDLVVVASDNL 129

Query: 111 FFGQGFSPKLRHVAARTEGATVFG-YQVMD---PERFGVVEFDDNFRAISLEEKPKQPKS 166
           F     S        + +   V G Y + D     ++GVV+FD N +    EEKP+ P +
Sbjct: 130 FNASLLS---FVEEGKAKNKPVVGIYNLKDKSLASKYGVVDFDRNKKLTFFEEKPQTPPT 186

Query: 167 NWAVTGLYFYDSKVVEYAKQ-VKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTG 225
            W    LYF+    + + K  +K  +  +     I  +Y        +L G    W D G
Sbjct: 187 TWVAMALYFFPKPSLTFLKAYLKEEKNADQPGRFIQWLYRREDVYVWQLPG---LWFDIG 243

Query: 226 THDSLIEAS 234
           + + L  A+
Sbjct: 244 SKEVLEAAN 252


>UniRef50_Q2FRV8 Nucleotidyl transferase n=1 Tax=Methanospirillum hungatei JF-1
           RepID=Q2FRV8_METHJ
          Length = 388

 Score = 65.5 bits (158), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 53/198 (26%), Positives = 90/198 (45%), Gaps = 14/198 (7%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           ++ +ILA G G RL P+T+   K L+P+ +KP+I + +  L+ AGIR+I+++     +  
Sbjct: 3   LQAVILAAGEGVRLRPLTQNKPKALIPVANKPIIEHTILSLLEAGIRDIIVVVGYRKEQV 62

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVL-GDNIFFGQGFSPK 119
            + L    +   + +    Q    G A A +     + G+   LVL GDN        P 
Sbjct: 63  MRHL----AHLSVPIMIVRQTEQLGTAHALLCARDRIAGD--VLVLPGDNY-----IDPD 111

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSK 179
                AR + + ++      P  FGVV  +D+  + S+ EKP          G+Y   S+
Sbjct: 112 SIRDIARIKNSLLYTTH-RQPSNFGVVTIEDDAVS-SITEKPVLASRMTVSCGVYHLGSE 169

Query: 180 VVEYAKQVKPSERGELEI 197
           ++        SE  + EI
Sbjct: 170 LLARITTQSLSEAIDEEI 187


>UniRef50_A9W818 Nucleotidyl transferase n=2 Tax=Rhizobiales RepID=A9W818_METEP
          Length = 238

 Score = 65.1 bits (157), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 63/229 (27%), Positives = 99/229 (43%), Gaps = 20/229 (8%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +I AGG GTRL P T  + K L+PI  KP++   +  L    I E+ I T     GY
Sbjct: 1   MKAVIQAGGRGTRLMPYTSVLPKPLMPIGAKPVLELLVKWLRRNAIEELYITT-----GY 55

Query: 61  FQRLL----GDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGF 116
              L+    GDG ++G+ + Y E+  P G   A  + E  L+   + LVL  ++      
Sbjct: 56  LGHLIRSFCGDGRQWGLHIVYTEETEPLGTIGALTLLEKHLD--ETFLVLNGDVLTDLSL 113

Query: 117 SPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFY 176
                   A  +  T+      +   FGV+E D +    S  EKP    +N    G+Y  
Sbjct: 114 RTFTGIHRAHGQPFTIATACRSNKLDFGVIE-DQDGVVTSFSEKPVL--TNSVSMGIYCM 170

Query: 177 DSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTG 225
           + +++++  +  P    +L         L A N+ + +      WLD G
Sbjct: 171 EPEILDHIPRGMPFGADDL------AHCLLAKNVPIHVYKHQGLWLDIG 213


>UniRef50_D0LZQ4 UTP-glucose-1-phosphate uridylyltransferase n=1 Tax=Haliangium
           ochraceum DSM 14365 RepID=D0LZQ4_HALO1
          Length = 298

 Score = 65.1 bits (157), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 63/234 (26%), Positives = 97/234 (41%), Gaps = 42/234 (17%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K +I A G GTR  P T+ + K++LPI DKP I   +   + AG+ +I+II      G  
Sbjct: 10  KAVIPAAGLGTRFLPATKAIPKEMLPIVDKPTIQLVVEEAVAAGMEDIVIIN-----GRQ 64

Query: 62  QRLLGDGSEFGIQLEY-------------------------AEQPSPDGLAQAFIIGETF 96
           +  + D  +   +LE+                           Q  P GL  A +     
Sbjct: 65  KVAIEDHFDHAFELEHTLRERSKDELLALSEQVSTMVRMVSVRQKRPLGLGHAVLCARPA 124

Query: 97  LNGEPSCLVLGDNIFF---GQGFSPKLRHVAARTEGATVFGYQVMDPER--FGVVEF--- 148
           +  EP  ++LGD++       G   +L  V ART    V   +V   E   +G+++    
Sbjct: 125 VGEEPFAVLLGDDLIDCDEAPGIG-QLAEVYARTGAGAVAVMEVQPGEEKLYGILDAEPM 183

Query: 149 -DDNFRAISLEEK--PKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITS 199
            D   R   + EK  PK   S  AV G Y    ++     +VKP   GE+++T 
Sbjct: 184 EDGLLRVRDMVEKPDPKDAPSRMAVIGRYVLPPEIWPILAEVKPGVGGEIQLTD 237


>UniRef50_P37820 Putative mannose-1-phosphate guanyltransferase n=12
           Tax=Sulfolobaceae RepID=MPG1_SULAC
          Length = 359

 Score = 65.1 bits (157), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 54/187 (28%), Positives = 87/187 (46%), Gaps = 13/187 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREI-LIITTPEDKG 59
           +  I+LAGG  TRL P++    K LLP+  KP++ Y L  L  + +  I L +    DK 
Sbjct: 2   VSAIVLAGGYATRLRPLSLTKPKALLPVLGKPLMDYTLYSLASSDVDTIYLSLRVMADK- 60

Query: 60  YFQRLLGDGSEFGIQLEYAEQPSPDGLAQA----FIIGETFLNGEPSCLVLGDNIFFGQG 115
               +L    +  +Q           L  A    FI  +  L+ +   +V+  +I+    
Sbjct: 61  ----VLDHVKQLNLQKNIVSVIEESRLGDAGPLKFINSKYNLSDD--VIVVYGDIYAEID 114

Query: 116 FSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYF 175
           F+  L +  ++   AT+   QV DP R+GV+   D  R I + EKPK P SN    G+Y 
Sbjct: 115 FNKLLEYHQSKGCNATLTATQVEDPSRYGVL-ITDGHRLIQIIEKPKTPLSNLVNAGIYV 173

Query: 176 YDSKVVE 182
           +  +++ 
Sbjct: 174 FKKELLN 180


>UniRef50_C1TQR0 UDP-glucose pyrophosphorylase n=1 Tax=Dethiosulfovibrio
           peptidovorans DSM 11002 RepID=C1TQR0_9BACT
          Length = 288

 Score = 65.1 bits (157), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 65/232 (28%), Positives = 103/232 (44%), Gaps = 38/232 (16%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKG- 59
           ++ I    G GTR  P T+ + K+++P+ D+P+I+Y +     +G   ++++T    KG 
Sbjct: 4   LECIFPVAGLGTRFLPATKEIPKEMVPLLDRPVIHYGVDEARNSGCSRMIMVTG-RSKGC 62

Query: 60  ---YF---------------QRLLG---DGSEFGIQLEYAEQPSPDGLAQAFIIGETFLN 98
              YF               +RLL    + S  G  L    Q +P GL  A + GE   N
Sbjct: 63  LEDYFDRSWELERILESRGKERLLDAVRETSSMGDILS-VRQSAPLGLGHAVLCGEPLCN 121

Query: 99  GEPSCLVLGDNIFFGQGFSPKLRHV--AARTEGATVFGY-QVMDPE--RFGVVEFDDN-- 151
           GE   ++L D++  GQ   P LR +     T G +V    +V D E  R+G+V  + +  
Sbjct: 122 GEFFSVILPDDVMEGQ--PPVLRQLMDVHDTLGGSVLALEEVSDAEVSRYGMVAVEPSGT 179

Query: 152 ---FRAISLEEKPK--QPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEIT 198
              FR   + EKP      S  AV G Y    ++ +  K       GE ++T
Sbjct: 180 EGIFRITDMVEKPSAADSPSRLAVMGRYVLSRRIFDLLKSQPKGAGGEYQLT 231


>UniRef50_A4E9G8 Putative uncharacterized protein n=1 Tax=Collinsella aerofaciens
           ATCC 25986 RepID=A4E9G8_9ACTN
          Length = 302

 Score = 65.1 bits (157), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 76/303 (25%), Positives = 124/303 (40%), Gaps = 45/303 (14%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPL-SVLMLAGIREILIITT---PE 56
           MK II A G GTR  P T+   K++LP+ DKP+I Y +   L    + + +I+T+   PE
Sbjct: 1   MKAIIPAAGLGTRFLPGTKCTPKEMLPVLDKPVIQYVVEEALDPEEVDDAIIVTSPGKPE 60

Query: 57  DKGYFQ------RLLGD----------GSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGE 100
              YFQ       LL +              G+ +++  Q  P GL  A       + GE
Sbjct: 61  LLSYFQPDRSLENLLRERGKDAYADAVAHAGGMPVDFRYQYEPKGLGHAIRSAADAVAGE 120

Query: 101 PSCLVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQVMDPE---RFGVVEFD-------- 149
              ++LGD +   +    K+  V+    GA+V       PE   R+GV+  D        
Sbjct: 121 NFLVLLGDYVVPNRDICDKMLAVSKEHGGASVIAVAACAPEEVSRYGVIAGDRVGSLEGF 180

Query: 150 ----DN-----FRAISLEEK--PKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEIT 198
               D+     +R   L EK  P+   SN  + G Y     V++     +  + GE+++T
Sbjct: 181 ENAADDEPGAVWRIGGLVEKPAPEAAPSNLYIVGRYLLSPLVMDLLADQQAGKGGEIQLT 240

Query: 199 SINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEKRQGFKIACLEEIAWRN 258
                 L+   +   ++    +  DTGT    +  +  +   + R  F  A  + I  R 
Sbjct: 241 DAMARSLDREAMYAVVIDP-LSGYDTGTPSGWMATNALMAASDPR--FAGAFWDAIDERG 297

Query: 259 GWL 261
           G +
Sbjct: 298 GLM 300


>UniRef50_A4I048 Mannose-1-phosphate guanyltransferase n=5 Tax=Leishmania
           RepID=A4I048_LEIIN
          Length = 379

 Score = 65.1 bits (157), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 55/243 (22%), Positives = 105/243 (43%), Gaps = 10/243 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +IL GG GTRL P+T    K L+P  +KPMI + +  L   G+ E+++      +  
Sbjct: 9   MRAVILVGGFGTRLRPLTLTTPKPLVPFCNKPMIIHQIEALKAVGVTEVILAVAYRPEAM 68

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIG-ETFLNGEPSCLVLGDNIFFGQGFSPK 119
            +++     + G+   ++ +  P G A    +  +  +  +    VL  ++         
Sbjct: 69  KEQMDEWSRKLGVSFVFSVEEEPLGTAGPLALARDILMQDDKPFFVLNSDVTCTFPMQEL 128

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFD-DNFRAISLEEKPKQPKSNWAVTGLYFYDS 178
           L    A     T+   QV   E++GVV +   N++     EKP +   +    G+Y ++ 
Sbjct: 129 LDFHKAHGGEGTIMVSQVTQWEKYGVVVYSPQNYQIERFVEKPSRFLGDRINAGIYIFNK 188

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGT-HDSLIEASTFV 237
            +++     + S   E+      +  L A NL       GF W+D G   D ++  + F+
Sbjct: 189 SILDRIPPRRTSIEKEIFPAMAAEGQLYAFNL------EGF-WMDVGQPKDYILGMTKFI 241

Query: 238 QTV 240
            ++
Sbjct: 242 PSL 244


>UniRef50_Q0FE70 UTP--glucose-1-phosphate uridylyltransferase (UDP-glucose
           pyrophosphorylase) (UDPGP) n=1 Tax=Rhodobacterales
           bacterium HTCC2255 RepID=Q0FE70_9RHOB
          Length = 303

 Score = 65.1 bits (157), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 65/288 (22%), Positives = 115/288 (39%), Gaps = 40/288 (13%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKG-- 59
           K +I   G GTR+ P T+ + K+LLPIYD+P+I + +   +  GIREI+ +T    +   
Sbjct: 9   KAVIPVAGLGTRMLPATKAIPKELLPIYDRPIIEHVVKEAIDGGIREIIFVTRSGKEAIE 68

Query: 60  -YF-------QRLLGDGSEF-----------GIQLEYAEQPSPDGLAQAFIIGETFLNGE 100
            +F        RL+  G               +++    Q    GL  A +  +  +N E
Sbjct: 69  NHFDAHYELEHRLVKKGKNKILEDIVKIIPDYVKISSIRQADALGLGHAILCAKHLINDE 128

Query: 101 PSCLVLGDNIFFGQGFSPKLRHVAARTEGATVFGY-QVM-------DPERFGVVEFDDN- 151
              ++L D +   +    K    +   +     G  QVM       D +++G+VE     
Sbjct: 129 AFAVLLPDVLIVDRKNRQKNFSFSHLMKAWNKTGIGQVMVERIDFDDTDKYGIVEMSKKN 188

Query: 152 --------FRAISLEEKPKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQM 203
                    +A+  + +P+   SN A+ G Y    ++  + + + P   GE+++T     
Sbjct: 189 INEFESAPLKALIEKPEPQNAPSNLALLGRYILPPQLFNFLEDINPGVGGEIQLTDALFK 248

Query: 204 YLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEKRQGFKIACL 251
            L   +L   L        D G     + A+  V   + +   KI  L
Sbjct: 249 LLTKKSLNAVLTDAHI--FDCGNKHGFLAANLLVGMQDPKTRTKIYAL 294


>UniRef50_Q11Z52 Glucose-1-phosphate thymidyltransferase n=2 Tax=Flexibacteraceae
           RepID=Q11Z52_CYTH3
          Length = 333

 Score = 64.7 bits (156), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 64/244 (26%), Positives = 108/244 (44%), Gaps = 20/244 (8%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPL-SVLMLAG--IREILIITTPED 57
           MK II   G G R+ P T  V K L+PI  K +++  +  +  + G  I E+  I     
Sbjct: 1   MKIIIPMAGMGKRMRPHTLTVPKPLVPIAGKAIVHRLVEDIAKVCGEKIEEVAFIIGDFG 60

Query: 58  KGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
           K   +RL+      G +     Q    G A A    +  L G+   +V   +  F   F+
Sbjct: 61  KETEKRLIKIAESVGAKGSIYYQREALGTAHAIYCAKESLGGK--VVVAFADTLFKADFT 118

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYD 177
                +    EG  ++  +V DP+ FGVV+ +D        EKP+   S+ A+ G+Y++ 
Sbjct: 119 -----LDTSNEG-IIWVQKVEDPKPFGVVKLNDKNEITDFVEKPEHFVSDLAIIGIYYFQ 172

Query: 178 S-----KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELL-GRGFAWLDTGTHDSLI 231
                 K ++Y       ++GE ++TS  +     G   ++ L G+   WLD G  DS +
Sbjct: 173 DGENLKKELQYVIDNDIKDKGEYQLTSALENMKNKG---IKFLPGKVTDWLDCGNKDSTV 229

Query: 232 EAST 235
           + ++
Sbjct: 230 DTNS 233


>UniRef50_Q5CTS3 Mannose-1-phosphate guanylyltransferase n=2 Tax=Cryptosporidium
           RepID=Q5CTS3_CRYPV
          Length = 425

 Score = 64.3 bits (155), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 48/201 (23%), Positives = 89/201 (44%), Gaps = 8/201 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK IIL+GG G+RL P+T    K ++ + + P+I + ++     GI EI++    +    
Sbjct: 30  MKAIILSGGYGSRLRPLTLTKPKSIVELCNIPIIEFQIAQFASIGITEIIVALNYKANEL 89

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
              L      + +++  + +  P G A    + + FL  +    V   +I         L
Sbjct: 90  IPTLKIIEDRYAVKVHLSIEEKPLGTAGPIKLAQDFLKEDEPFFVCNSDIICNFPLREML 149

Query: 121 RHVAARTEGATVFGY----QVMDPERFGVVEFDDNFRAI-SLEEKPKQPKSNWAVTGLYF 175
                +   +   G     QV DP +FGVV  D+N   +    EKPK    ++   G+Y 
Sbjct: 150 DLYHKKNSDSECNGVILIKQVSDPSKFGVVLHDENTLIVEKFIEKPKDFVGDFINAGIYI 209

Query: 176 YDSKVVEYAKQVKPSERGELE 196
              ++++    +KP+++  +E
Sbjct: 210 LSKRILDL---IKPNQQVSIE 227


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_Q5DIE4 Glucose-1-phosphate thymidylyltransferase n=109 ...   341   2e-92
UniRef50_P55253 Glucose-1-phosphate thymidylyltransferase n=1508...   328   1e-88
UniRef50_Q6MF02 Glucose-1-phosphate thymidylyltransferase n=3 Ta...   328   2e-88
UniRef50_C0LTM3 Glucose-1-phosphate thymidylyltransferase n=6 Ta...   309   7e-83
UniRef50_C7XIA2 Glucose-1-phosphate thymidylyltransferase n=1 Ta...   296   8e-79
UniRef50_Q9ZAE7 Glucose-1-phosphate thymidylyltransferase n=12 T...   292   1e-77
UniRef50_D1Y1R8 Glucose-1-phosphate thymidylyltransferase n=1 Ta...   290   4e-77
UniRef50_C7IJC3 Glucose-1-phosphate thymidylyltransferase n=1 Ta...   282   1e-74
UniRef50_D0RRF5 Glucose-1-phosphate thymidylyltransferase (DTDP-...   259   9e-68
UniRef50_C7NU65 Glucose-1-phosphate thymidyltransferase n=5 Tax=...   255   1e-66
UniRef50_Q55689 Glucose-1-phosphate thymidylyltransferase n=52 T...   249   9e-65
UniRef50_A7HN10 Glucose-1-phosphate thymidyltransferase n=9 Tax=...   241   2e-62
UniRef50_Q46AY8 Glucose-1-phosphate thymidylyltransferase n=4 Ta...   240   5e-62
UniRef50_A3DED2 Nucleotidyl transferase n=8 Tax=Clostridium RepI...   239   9e-62
UniRef50_UPI0001C418F3 UDP-N-acetylglucosamine diphosphorylase/g...   237   3e-61
UniRef50_C8W233 Nucleotidyl transferase n=1 Tax=Desulfotomaculum...   235   1e-60
UniRef50_P39629 Spore coat polysaccharide biosynthesis protein s...   235   1e-60
UniRef50_A5D3D6 dTDP-glucose pyrophosphorylase n=5 Tax=Bacteria ...   235   2e-60
UniRef50_Q2NES5 Predicted nucleoside-diphosphate-sugar pyrophosp...   234   3e-60
UniRef50_Q9X3S7 Glucose-1-phosphate thymidyl transferase n=1 Tax...   233   6e-60
UniRef50_B5YF33 Mannose-1-phosphate guanyltransferase n=2 Tax=Di...   232   1e-59
UniRef50_UPI0001C42A13 Nucleoside-diphosphate-sugar pyrophosphor...   231   2e-59
UniRef50_C0ZG53 Probable mannose-1-phosphate guanyltransferase n...   230   4e-59
UniRef50_A5N939 Predicted glucose-1-phosphate nucleotidyltransfe...   230   4e-59
UniRef50_Q3A0B4 Mannose-1-phosphate guanyltransferase n=10 Tax=D...   229   1e-58
UniRef50_C9RWA3 Nucleotidyl transferase n=7 Tax=Geobacillus RepI...   229   1e-58
UniRef50_A4J6Z1 Nucleotidyl transferase n=3 Tax=Peptococcaceae R...   228   1e-58
UniRef50_B5GLJ2 NDP-1-glucose synthase n=1 Tax=Streptomyces clav...   228   2e-58
UniRef50_Q97A91 Glucose-1-phosphate thymidylyltransferase n=2 Ta...   228   2e-58
UniRef50_C0ZCI7 Probable glucose-1-phosphate thymidylyltransfera...   228   2e-58
UniRef50_UPI000038E60D glucose-1-phosphate thymidylyltransferase...   228   2e-58
UniRef50_C7LZ98 Nucleotidyl transferase n=1 Tax=Acidimicrobium f...   228   2e-58
UniRef50_Q01T68 Nucleotidyl transferase n=8 Tax=cellular organis...   228   2e-58
UniRef50_O29921 Glucose-1-phosphate thymidylyltransferase (GraD-...   228   2e-58
UniRef50_Q8TWY9 Nucleoside-diphosphate-sugar pyrophosphorylase i...   227   2e-58
UniRef50_A7GF11 Glucose-1-phosphate thymidylyltransferase n=9 Ta...   227   3e-58
UniRef50_A8KY05 Nucleotidyl transferase n=6 Tax=Actinomycetales ...   227   3e-58
UniRef50_A8FIL3 Spore coat polysaccharide biosynthesis protein S...   227   5e-58
UniRef50_B8CYH8 Phosphoglucomutase n=1 Tax=Halothermothrix oreni...   226   6e-58
UniRef50_D2AV47 Phosphoglucomutase/phosphomannomutase family pro...   226   7e-58
UniRef50_Q2RH64 Nucleotidyl transferase n=1 Tax=Moorella thermoa...   226   7e-58
UniRef50_A9B3S0 Nucleotidyl transferase n=6 Tax=Chloroflexi (cla...   226   8e-58
UniRef50_Q1J1J1 Glucose-1-phosphate thymidyltransferase n=10 Tax...   225   9e-58
UniRef50_C0GEN7 Nucleotidyl transferase n=1 Tax=Dethiobacter alk...   225   1e-57
UniRef50_A3DK29 Nucleotidyl transferase n=13 Tax=Clostridia RepI...   225   1e-57
UniRef50_UPI0001C3666A glucose-1-phosphate thymidylyltransferase...   224   3e-57
UniRef50_A7GSW4 Nucleotidyl transferase n=73 Tax=cellular organi...   223   6e-57
UniRef50_Q3Z778 Nucleotidyltransferase family protein n=5 Tax=De...   222   1e-56
UniRef50_B9MMF1 Nucleotidyl transferase n=1 Tax=Anaerocellum the...   222   1e-56
UniRef50_A7NP37 Nucleotidyl transferase n=5 Tax=Chloroflexaceae ...   221   2e-56
UniRef50_D2PJ00 Glucose-1-phosphate thymidyltransferase n=15 Tax...   221   2e-56
UniRef50_B8I5R7 Nucleotidyl transferase n=1 Tax=Clostridium cell...   221   2e-56
UniRef50_C3LKU6 Nucleotidyl transferase family protein n=8 Tax=B...   221   3e-56
UniRef50_B9KYJ6 Glucose-1-phosphate thymidylyltransferase n=5 Ta...   221   3e-56
UniRef50_C7ICW0 Nucleotidyl transferase n=1 Tax=Clostridium papy...   220   3e-56
UniRef50_P08075 Glucose-1-phosphate thymidylyltransferase n=49 T...   220   3e-56
UniRef50_A3DL04 Nucleotidyl transferase n=1 Tax=Staphylothermus ...   220   6e-56
UniRef50_A0Q1V6 Mannose-1-phosphate guanyltransferase (Pyrophosp...   220   6e-56
UniRef50_C1DV53 Mannose-1-phosphate guanyltransferase n=4 Tax=ce...   219   7e-56
UniRef50_B7GHA3 Nucleoside-diphosphate-sugar pyrophosphorylase f...   219   9e-56
UniRef50_Q97EX5 Mannose-1-phosphate guanyltransferase (Pyrophosp...   219   9e-56
UniRef50_Q8CUH8 Spore coat polysaccharide synthesis (Glucose-1-p...   219   1e-55
UniRef50_Q1AW30 Nucleotidyl transferase n=1 Tax=Rubrobacter xyla...   219   1e-55
UniRef50_A4YHT6 Glucose-1-phosphate thymidyltransferase n=1 Tax=...   219   1e-55
UniRef50_C6D3B0 Nucleotidyl transferase n=1 Tax=Paenibacillus sp...   219   1e-55
UniRef50_C1SHR4 Nucleotidyltransferase n=1 Tax=Denitrovibrio ace...   218   2e-55
UniRef50_Q8SQX7 MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE n=3 Tax=...   217   2e-55
UniRef50_B0BZX4 Phosphoglucomutase/phosphomannomutase family Nuc...   217   4e-55
UniRef50_UPI0001C315BB Nucleotidyl transferase n=1 Tax=Conexibac...   216   7e-55
UniRef50_D1JGY1 Putative bifunctional protein glmU n=1 Tax=uncul...   215   9e-55
UniRef50_B8LVX3 Mannose-1-phosphate guanylyltransferase n=2 Tax=...   215   1e-54
UniRef50_A6TTZ6 Nucleotidyl transferase n=1 Tax=Alkaliphilus met...   215   1e-54
UniRef50_A9A1Q3 Glucose-1-phosphate thymidyltransferase n=1 Tax=...   215   1e-54
UniRef50_Q9KD03 Mannose-1-phosphate guanyltransferase n=1 Tax=Ba...   215   1e-54
UniRef50_Q0W4J0 Glucose-1-phosphate thymidylyltransferase n=2 Ta...   215   1e-54
UniRef50_B3QV42 Nucleotidyl transferase n=1 Tax=Chloroherpeton t...   215   2e-54
UniRef50_Q7NNE0 Mannose-1-phosphate guanyltransferase n=5 Tax=Gl...   214   2e-54
UniRef50_C6A0S3 Nucleotidyl transferase family n=6 Tax=Thermococ...   214   3e-54
UniRef50_C0E9C6 Putative uncharacterized protein n=1 Tax=Clostri...   214   4e-54
UniRef50_C0GGS0 Nucleotidyl transferase n=1 Tax=Dethiobacter alk...   213   6e-54
UniRef50_A6CNU8 Mannose-1-phosphate guanyltransferase (Pyrophosp...   213   6e-54
UniRef50_UPI0001693120 glucose-1-phosphate thymidyltransferase n...   213   7e-54
UniRef50_Q8DLP2 Mannose-1-phosphate guanyltransferase n=9 Tax=Cy...   212   8e-54
UniRef50_A6Q9R9 Mannose-1-phosphate guanylyltransferase n=3 Tax=...   212   1e-53
UniRef50_A7AUL2 Mannose-1-phosphate guanyltransferase, putative ...   211   2e-53
UniRef50_B0K747 Nucleotidyl transferase n=10 Tax=Thermoanaerobac...   210   3e-53
UniRef50_C6A1S5 NDP-sugar synthase n=9 Tax=Thermococcaceae RepID...   210   4e-53
UniRef50_A8LZU8 Glucose-1-phosphate thymidyltransferase n=15 Tax...   209   8e-53
UniRef50_Q0AV26 Mannose-1-phosphate guanyltransferase n=1 Tax=Sy...   209   1e-52
UniRef50_B3LAG9 Mannose-1-phosphate guanyltransferase, putative ...   209   1e-52
UniRef50_Q8ILP1 Mannose-1-phosphate guanyltransferase, putative ...   207   2e-52
UniRef50_B0BLL5 dTDP-1-glucose synthase n=1 Tax=Actinomadura mad...   207   3e-52
UniRef50_Q46AY5 Glucose-1-phosphate thymidylyltransferase n=4 Ta...   207   5e-52
UniRef50_D2RY68 Nucleotidyl transferase n=2 Tax=Halobacteriaceae...   206   7e-52
UniRef50_Q74B34 Nucleotidyltransferase family protein n=1 Tax=Ge...   205   2e-51
UniRef50_B0PFA5 Putative uncharacterized protein n=1 Tax=Anaerot...   205   2e-51
UniRef50_A6UUQ4 Glucosamine-1-phosphate N-acetyltransferase n=6 ...   204   3e-51
UniRef50_C8NLU6 Mannose-1-phosphate guanyltransferase n=88 Tax=A...   204   3e-51
UniRef50_UPI000038E164 mannose-1-phosphate guanyltransferase n=1...   204   4e-51
UniRef50_C7LY80 Nucleotidyl transferase n=1 Tax=Acidimicrobium f...   204   4e-51
UniRef50_O27787 Mannose-1-phosphate guanyltransferase n=1 Tax=Me...   203   5e-51
UniRef50_B9LMT7 Nucleotidyl transferase n=2 Tax=Halobacteriaceae...   203   5e-51
UniRef50_Q1ASA7 Nucleotidyl transferase n=1 Tax=Rubrobacter xyla...   203   6e-51
UniRef50_UPI000186E54F Mannose-1-phosphate guanyltransferase, pu...   203   6e-51
UniRef50_UPI000197A125 nucleotidyl transferase n=1 Tax=Helicobac...   202   9e-51
UniRef50_A6UP85 Glucosamine-1-phosphate N-acetyltransferase n=6 ...   202   9e-51
UniRef50_C6PCK2 Nucleotidyl transferase n=1 Tax=Thermoanaerobact...   202   9e-51
UniRef50_A4I048 Mannose-1-phosphate guanyltransferase n=5 Tax=Le...   202   1e-50
UniRef50_B8D5T2 Putative sugar-phosphate nucleotidyl transferase...   202   1e-50
UniRef50_A8GZ91 Nucleotidyl transferase n=5 Tax=Gammaproteobacte...   202   1e-50
UniRef50_Q6L165 Mannose-1-phosphate guanyltransferase n=3 Tax=Th...   202   1e-50
UniRef50_Q23RS7 Nucleotidyl transferase family protein n=3 Tax=E...   202   2e-50
UniRef50_Q12TW4 Mannose-1-phosphate guanyltransferase n=11 Tax=E...   202   2e-50
UniRef50_B0R8I5 Sugar nucleotidyltransferase n=2 Tax=Halobacteri...   201   2e-50
UniRef50_A9A224 Nucleotidyl transferase n=3 Tax=Thaumarchaeota R...   201   3e-50
UniRef50_Q2WB86 Nucleoside-diphosphate-sugar pyrophosphorylase n...   200   4e-50
UniRef50_Q2FRV9 Nucleotidyl transferase n=7 Tax=cellular organis...   200   6e-50
UniRef50_C8SCM3 Nucleotidyl transferase n=1 Tax=Ferroglobus plac...   199   1e-49
UniRef50_A0B7L5 Nucleotidyl transferase n=1 Tax=Methanosaeta the...   199   1e-49
UniRef50_Q67QD8 Putative mannose-1-phosphate guanyltransferase n...   198   2e-49
UniRef50_C7LVF0 Nucleotidyl transferase n=2 Tax=Proteobacteria R...   197   4e-49
UniRef50_Q28JE9 Nucleotidyl transferase n=1 Tax=Jannaschia sp. C...   197   4e-49
UniRef50_B1XM99 Sugar-phosphate nucleotidyl transferase n=59 Tax...   197   5e-49
UniRef50_A8G626 Nucleoside-diphosphate-sugar pyrophosphorylase n...   197   5e-49
UniRef50_A3CRY9 UDP-glucose pyrophosphorylase n=2 Tax=Methanomic...   196   8e-49
UniRef50_Q8YRP4 Mannose-1-phosphate guanyltransferase n=11 Tax=B...   195   1e-48
UniRef50_C4SU82 Nucleoside-diphosphate-sugar pyrophosphorylase i...   195   1e-48
UniRef50_Q97EQ2 Nucleoside-diphosphate-sugar pyrophosphorylase n...   195   1e-48
UniRef50_D2EEI5 Nucleotidyl transferase n=1 Tax=Candidatus Parva...   195   2e-48
UniRef50_C0G2T6 Nucleotidyl transferase n=1 Tax=Natrialba magadi...   195   2e-48
UniRef50_Q1AVJ3 Nucleotidyl transferase n=1 Tax=Rubrobacter xyla...   194   2e-48
UniRef50_Q5CTS3 Mannose-1-phosphate guanylyltransferase n=2 Tax=...   194   3e-48
UniRef50_A8A970 Nucleotidyl transferase n=1 Tax=Ignicoccus hospi...   194   3e-48
UniRef50_A9CZR8 Nucleotidyl transferase n=1 Tax=Hoeflea phototro...   194   3e-48
UniRef50_B5GDG2 Nucleotide phosphorylase n=1 Tax=Streptomyces sp...   194   4e-48
UniRef50_A3DMT9 Nucleotidyl transferase n=11 Tax=Thermoprotei Re...   193   6e-48
UniRef50_UPI0001C16C8D Mannose-1-phosphate guanyltransferase CBS...   193   7e-48
UniRef50_B6BGD8 Nucleotidyl transferase n=1 Tax=Campylobacterale...   193   8e-48
UniRef50_Q3AQC4 Glucose-1-phosphate thymidylyltransferase n=12 T...   193   8e-48
UniRef50_Q18G10 Glucose-1-phosphate thymidylyltransferase n=5 Ta...   192   9e-48
UniRef50_Q4UEZ4 GDP-mannose pyrophosphorylase, putative n=2 Tax=...   192   9e-48
UniRef50_Q0G1T6 Nucleotidyl transferase n=1 Tax=Fulvimarina pela...   192   1e-47
UniRef50_Q3Z925 Glucose-1-phosphate thymidylyltransferase n=5 Ta...   192   1e-47
UniRef50_Q3SPZ3 Nucleotidyl transferase n=1 Tax=Nitrobacter wino...   192   2e-47
UniRef50_UPI0001C315B1 Nucleotidyl transferase n=1 Tax=Conexibac...   192   2e-47
UniRef50_Q2LPS3 Glucose-1-phosphate adenylyltransferase n=3 Tax=...   192   2e-47
UniRef50_B0BZ78 Nucleotidyl transferase protein n=5 Tax=Cyanobac...   192   2e-47
UniRef50_B8D6C9 Glucose-1-phosphate thymidylyltransferase n=1 Ta...   191   2e-47
UniRef50_C7P380 Nucleotidyl transferase n=20 Tax=Halobacteriacea...   191   2e-47
UniRef50_Q26CD7 Putative nucleoside diphosphate sugar pyrophosph...   191   2e-47
UniRef50_Q1J1Y9 Nucleotidyl transferase n=2 Tax=Deinococcus RepI...   191   3e-47
UniRef50_Q1Q6W7 Putative uncharacterized protein n=2 Tax=Bacteri...   190   4e-47
UniRef50_A3DNE2 Nucleotidyl transferase n=8 Tax=Thermoprotei Rep...   190   4e-47
UniRef50_Q6MME9 Mannose-1-phosphate guanyltransferase n=1 Tax=Bd...   189   9e-47
UniRef50_B7XJS8 Mannose-1-phosphate guanyltransferase n=1 Tax=En...   189   1e-46
UniRef50_A6C2H5 Nucleoside-diphosphate-sugar pyrophosphorylase n...   189   1e-46
UniRef50_A0ADR0 Putative nucleoside-diphosphate-sugar pyrophosph...   189   1e-46
UniRef50_Q9YCT0 Glucose-1-phosphate thymidylyltransferase n=1 Ta...   189   1e-46
UniRef50_Q7U909 Putative sugar-phosphate nucleotide transferase ...   188   2e-46
UniRef50_B9LW43 Nucleotidyl transferase n=5 Tax=Halobacteriaceae...   188   2e-46
UniRef50_C5A4I2 Sugar-phosphate nucleotydyltransferase n=9 Tax=T...   188   3e-46
UniRef50_A7NP68 Nucleotidyl transferase n=2 Tax=Roseiflexus RepI...   187   3e-46
UniRef50_C9LPM2 Nucleotidyl transferase family enzyme n=1 Tax=Di...   187   4e-46
UniRef50_B5HPZ4 Nucleotide phosphorylase n=1 Tax=Streptomyces sv...   187   4e-46
UniRef50_B0VGT1 Putative Mannose-1-phosphate guanylyltransferase...   187   5e-46
UniRef50_B1HN58 Mannose-1-phosphate guanyltransferase 2 n=5 Tax=...   187   5e-46
UniRef50_A8MDH4 Nucleotidyl transferase n=6 Tax=Thermoproteaceae...   187   5e-46
UniRef50_A9W818 Nucleotidyl transferase n=2 Tax=Rhizobiales RepI...   186   7e-46
UniRef50_B1BCE9 Nucleotidyl transferase n=2 Tax=Clostridium RepI...   186   8e-46
UniRef50_D0KYG3 Nucleotidyl transferase n=30 Tax=cellular organi...   186   9e-46
UniRef50_C5VTI3 Nucleotidyl transferase n=1 Tax=Clostridium botu...   185   1e-45
UniRef50_A7ZFS2 Nucleotidyl transferase n=3 Tax=Proteobacteria R...   185   2e-45
UniRef50_B4SDB4 Nucleotidyl transferase n=1 Tax=Pelodictyon phae...   185   2e-45
UniRef50_A9FF13 Putative sugar-phosphate nucleotide transferase ...   185   2e-45
UniRef50_B8IAD4 Nucleotidyl transferase n=1 Tax=Methylobacterium...   185   2e-45
UniRef50_C7NR86 Nucleotidyl transferase n=4 Tax=Halobacteriaceae...   184   2e-45
UniRef50_A0L542 Nucleotidyl transferase n=2 Tax=Proteobacteria R...   184   3e-45
UniRef50_Q0W734 Nucleotidyltransferase family protein n=2 Tax=Eu...   184   3e-45
UniRef50_A2C5W2 Nucleoside-diphosphate-sugar pyrophosphorylase n...   184   3e-45
UniRef50_Q30U75 Nucleotidyl transferase n=3 Tax=Proteobacteria R...   184   4e-45
UniRef50_A1WSE0 Nucleotidyl transferase n=1 Tax=Verminephrobacte...   184   5e-45
UniRef50_D2LMS4 Nucleotidyl transferase n=3 Tax=Aciduliprofundum...   182   1e-44
UniRef50_C7NV90 Nucleotidyl transferase n=1 Tax=Halorhabdus utah...   182   1e-44
UniRef50_B5EDT7 Nucleotidyl transferase n=5 Tax=Bacteria RepID=B...   182   1e-44
UniRef50_Q5HT82 Nucleotidyltransferase family protein n=11 Tax=C...   182   1e-44
UniRef50_A9B2A2 Nucleotidyl transferase n=1 Tax=Herpetosiphon au...   182   1e-44
UniRef50_B7KYN3 Nucleotidyl transferase n=1 Tax=Methylobacterium...   182   2e-44
UniRef50_B2VWC7 Mannose-1-phosphate guanyltransferase n=2 Tax=Le...   182   2e-44
UniRef50_C4XP25 Nucleotidyl transferase domain protein n=3 Tax=P...   181   2e-44
UniRef50_B3T1I2 Putative Nucleotidyl transferase n=1 Tax=uncultu...   181   3e-44
UniRef50_C2G0W6 Nucleotidyl transferase n=1 Tax=Sphingobacterium...   180   3e-44
UniRef50_D1PXL9 Mannose-1-phosphate guanyltransferase n=2 Tax=Ba...   180   4e-44
UniRef50_Q036S8 Glucose-1-phosphate adenylyltransferase n=9 Tax=...   180   4e-44
UniRef50_Q31FM5 Nucleotidyl transferase n=1 Tax=Thiomicrospira c...   180   4e-44
UniRef50_C6VS96 Nucleotidyl transferase n=1 Tax=Dyadobacter ferm...   180   4e-44
UniRef50_Q0W805 Putative glucose-1-phosphate thymidylyltransfera...   180   5e-44
UniRef50_D2RP80 Nucleotidyl transferase n=2 Tax=Haloterrigena tu...   180   6e-44
UniRef50_Q5UXR9 Glucose-1-phosphate thymidylyltransferase n=2 Ta...   180   7e-44
UniRef50_A1VGN4 Nucleotidyl transferase n=1 Tax=Desulfovibrio vu...   179   8e-44
UniRef50_C4PX01 Gdp-mannose pyrophosphorylase b, isoform 2 n=1 T...   179   8e-44
UniRef50_B3PKU9 Nucleotidyltransferase family protein n=1 Tax=Ce...   178   1e-43
UniRef50_A8RPP5 Putative uncharacterized protein n=2 Tax=Clostri...   178   1e-43
UniRef50_P37820 Putative mannose-1-phosphate guanyltransferase n...   178   1e-43
UniRef50_A4WLA7 Nucleotidyl transferase n=6 Tax=Thermoproteaceae...   178   1e-43
UniRef50_A8MC98 Nucleotidyl transferase n=1 Tax=Caldivirga maqui...   178   1e-43
UniRef50_Q67RD1 Glucose-1-phosphate thymidylyltransferase n=1 Ta...   178   2e-43
UniRef50_C5ELG1 HAD-superfamily protein n=2 Tax=Clostridiales Re...   178   2e-43
UniRef50_Q54800 UTP--glucose-1-phosphate uridylyltransferase n=1...   178   2e-43
UniRef50_A4BEN1 Nucleoside-diphosphate-sugar pyrophosphorylase n...   178   2e-43
UniRef50_A9VB22 Predicted protein n=1 Tax=Monosiga brevicollis R...   178   2e-43
UniRef50_C6X012 Glucose-1-phosphate thymidylyltransferase n=17 T...   178   2e-43
UniRef50_A7GGU6 Nucleotidyl transferase family protein n=4 Tax=C...   178   3e-43
UniRef50_Q01PZ9 UDP-glucose pyrophosphorylase n=1 Tax=Candidatus...   178   3e-43
UniRef50_A6TK87 UTP-glucose-1-phosphate uridylyltransferase n=5 ...   177   3e-43
UniRef50_Q7X521 PtmE n=1 Tax=Campylobacter coli RepID=Q7X521_CAMCO    177   3e-43
UniRef50_C8PUN5 Utp--glucose-1-phosphate uridylyltransferase n=1...   177   3e-43
UniRef50_B0THI4 D,d-heptose 1,7-bisphosphate phosphatase subfami...   177   3e-43
UniRef50_B6AEL1 Nucleotidyl transferase family protein n=1 Tax=C...   177   6e-43
UniRef50_B5ZR76 Nucleotidyl transferase n=12 Tax=Bacteria RepID=...   176   6e-43
UniRef50_B8FX62 Glucose-1-phosphate adenylyltransferase n=2 Tax=...   176   6e-43
UniRef50_Q49VP4 UTP--glucose-1-phosphate uridylyltransferase 2 n...   176   8e-43
UniRef50_D2PFA0 Nucleotidyl transferase n=10 Tax=Sulfolobus RepI...   175   1e-42
UniRef50_A1S194 UDP-glucose pyrophosphorylase n=1 Tax=Thermofilu...   175   1e-42
UniRef50_C9XS92 Utp--glucose-1-phosphate uridylyltransferase (Ge...   175   2e-42
UniRef50_D0XT48 Nucleotidyl transferase n=1 Tax=Brevundimonas su...   175   2e-42
UniRef50_A1S0Y5 UDP-glucose pyrophosphorylase n=1 Tax=Thermofilu...   175   2e-42
UniRef50_D2EEQ5 Nucleotidyl transferase n=1 Tax=Candidatus Parva...   174   3e-42
UniRef50_A3JPT4 Putative sugar-phosphate nucleotidyl transferase...   174   3e-42
UniRef50_Q9I291 UTP--glucose-1-phosphate uridylyltransferase n=1...   174   4e-42
UniRef50_Q8DE01 Nucleoside-diphosphate-sugar pyrophosphorylase n...   173   4e-42
UniRef50_C2KXR6 Glucose-1-phosphate cytidylyltransferase n=1 Tax...   173   5e-42
UniRef50_D1C4F4 Nucleotidyl transferase n=1 Tax=Sphaerobacter th...   173   6e-42
UniRef50_C1VEK9 Nucleoside-diphosphate-sugar pyrophosphorylase f...   173   6e-42
UniRef50_A2U039 Nucleotidyl transferase n=1 Tax=Polaribacter sp....   173   7e-42
UniRef50_Q1LK18 UDP-glucose pyrophosphorylase n=21 Tax=Proteobac...   173   8e-42
UniRef50_A3WUE7 Nucleoside-diphosphate-sugar pyrophosphorylase n...   173   8e-42
UniRef50_A2EDD6 Nucleotidyl transferase family protein n=2 Tax=T...   173   8e-42
UniRef50_A4E9G8 Putative uncharacterized protein n=1 Tax=Collins...   172   9e-42
UniRef50_P0C0I9 UTP--glucose-1-phosphate uridylyltransferase 1 n...   172   1e-41
UniRef50_C4RN52 UTP-glucose-1-phosphate uridylyltransferase galU...   172   1e-41
UniRef50_B9CMC2 Glucose-1-phosphate adenylyltransferase n=1 Tax=...   172   1e-41
UniRef50_A4X2X2 UDP-glucose pyrophosphorylase n=3 Tax=Actinomyce...   172   1e-41
UniRef50_B2UH51 UTP-glucose-1-phosphate uridylyltransferase n=12...   172   2e-41
UniRef50_A8M980 Glucose-1-phosphate thymidyltransferase n=3 Tax=...   171   2e-41
UniRef50_C7M360 UTP-glucose-1-phosphate uridylyltransferase n=2 ...   171   2e-41
UniRef50_C9RJ30 Nucleotidyl transferase n=1 Tax=Fibrobacter succ...   170   4e-41
UniRef50_C7PVA0 Nucleotidyl transferase n=3 Tax=Bacteroidetes Re...   170   4e-41
UniRef50_A9BBF8 Nucleoside-diphosphate-sugar pyrophosphorylase n...   170   4e-41
UniRef50_B4U0Q7 UTP--glucose-1-phosphate uridylyltransferase Has...   170   5e-41
UniRef50_Q3K1K4 Glucose-1-phosphate adenylyltransferase n=14 Tax...   170   5e-41

Sequences not found previously or not previously below threshold:

>UniRef50_Q5DIE4 Glucose-1-phosphate thymidylyltransferase n=109 Tax=Bacteria
           RepID=Q5DIE4_ECOLX
          Length = 290

 Score =  341 bits (875), Expect = 2e-92,   Method: Composition-based stats.
 Identities = 216/288 (75%), Positives = 240/288 (83%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPM+YYP+SVLMLAGIR+IL+ITTPED   
Sbjct: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMVYYPMSVLMLAGIRDILLITTPEDLPS 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F+RLLGDGS FGI L Y  Q SPDGL QAFIIGE F+  +   LVLGDNIFFGQ F  KL
Sbjct: 61  FKRLLGDGSRFGINLSYEIQQSPDGLVQAFIIGEEFIADDKCALVLGDNIFFGQSFGRKL 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
             V +   GATVFGYQVMDPERFGVVEFD NF+A+S+EEKP  PKSNWAVTGLYFYD  V
Sbjct: 121 ESVVSGNAGATVFGYQVMDPERFGVVEFDKNFKALSIEEKPAAPKSNWAVTGLYFYDENV 180

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           V+ AK VKPS RGELEIT++N+MYLE GNL VELLGRGFAWLDTGTHDSLIEAS F+ T+
Sbjct: 181 VDMAKCVKPSARGELEITTLNEMYLEQGNLQVELLGRGFAWLDTGTHDSLIEASQFIHTI 240

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRA 288
           EKRQGFKIACLEEIA+RNGWL +  V    + ++KT YGQYLL L++ 
Sbjct: 241 EKRQGFKIACLEEIAYRNGWLTESEVVTYGNEMSKTNYGQYLLNLIKN 288


>UniRef50_P55253 Glucose-1-phosphate thymidylyltransferase n=1508 Tax=cellular
           organisms RepID=RMLA3_ECOLX
          Length = 293

 Score =  328 bits (842), Expect = 1e-88,   Method: Composition-based stats.
 Identities = 189/288 (65%), Positives = 230/288 (79%), Gaps = 1/288 (0%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           KGIILAGGSGTRL+P+T  VSKQLLPIYDKPMIYYPLS LMLAGIR+ILII+TP+D   F
Sbjct: 5   KGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPRF 64

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLR 121
           Q+LLGDGS++G+ L+Y  QPSPDGLAQAFIIGE F+ G+   LVLGDNIF+G      + 
Sbjct: 65  QQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEDFIGGDDCALVLGDNIFYGHDLPKLME 124

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVV 181
               +  GATVF Y V DPER+GVVEFD+N  AISLEEKP +PKSN+AVTGLYFYD+ VV
Sbjct: 125 AAVNKESGATVFAYHVNDPERYGVVEFDNNGTAISLEEKPLEPKSNYAVTGLYFYDNDVV 184

Query: 182 EYAK-QVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           E A+  +KPS RGELEIT IN++Y+E G L+V ++GRG+AWLDTGTH SLIEAS F+ T+
Sbjct: 185 EMARKNLKPSARGELEITDINRIYMEQGRLSVAMMGRGYAWLDTGTHQSLIEASNFIATI 244

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRA 288
           E+RQG K++C EEIA+R G++D E VK  A  L K  YGQYLL++++ 
Sbjct: 245 EERQGLKVSCPEEIAYRKGFIDAEQVKVLAEPLKKNAYGQYLLKMIKG 292


>UniRef50_Q6MF02 Glucose-1-phosphate thymidylyltransferase n=3 Tax=Bacteria
           RepID=Q6MF02_PARUW
          Length = 295

 Score =  328 bits (841), Expect = 2e-88,   Method: Composition-based stats.
 Identities = 169/290 (58%), Positives = 218/290 (75%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKGI+LAGGSGTRLHP+T GV+KQLLP+Y+KPMIYYPLSVL+LA I++ILII+TPED   
Sbjct: 1   MKGIVLAGGSGTRLHPLTLGVTKQLLPVYNKPMIYYPLSVLLLAEIKDILIISTPEDMPV 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F+RLLGDGS  G++  Y  QP P+GLA+AFIIG+ F+  +  CLVLGDNIF+G   S  L
Sbjct: 61  FKRLLGDGSHLGVRFTYEMQPKPNGLAEAFIIGKDFIGKDSVCLVLGDNIFYGSHLSNLL 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           +    + EGAT+FGY+V DPER+GVVEFD   + +S+EEKPK PKS+ AVTGLYFYD++V
Sbjct: 121 KSAKEKKEGATLFGYEVKDPERYGVVEFDGQGKILSIEEKPKIPKSSIAVTGLYFYDNQV 180

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           V+ A  +KPS RGELEIT +NQ YL      V ++GRG+ WLD GT++SL++AS FVQ +
Sbjct: 181 VDIAHGLKPSARGELEITDVNQEYLNRDQACVHVMGRGYTWLDAGTYESLMQASQFVQVI 240

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRARP 290
           E+RQG  IA LEEIA+   ++    +K     L K+ YG+YL+E+    P
Sbjct: 241 EQRQGHCIASLEEIAYNQKFISQAQLKLLGEKLGKSLYGRYLMEIAEKGP 290


>UniRef50_C0LTM3 Glucose-1-phosphate thymidylyltransferase n=6 Tax=Actinomycetales
           RepID=C0LTM3_9ACTO
          Length = 331

 Score =  309 bits (792), Expect = 7e-83,   Method: Composition-based stats.
 Identities = 157/293 (53%), Positives = 204/293 (69%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKGII+AGGSG+RL P+T  +SKQLLP+Y+KPMIYYPLSVLMLAG+ E+LII++P+    
Sbjct: 1   MKGIIMAGGSGSRLKPLTGVLSKQLLPVYNKPMIYYPLSVLMLAGVTEVLIISSPQHLPL 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F+ +LGDG   G++L YAEQ  P G+A+AF+IG   +  +   LVLGDNIF G GFS  L
Sbjct: 61  FRAMLGDGDRLGMRLTYAEQHRPAGIAEAFLIGAGHIGDDSVSLVLGDNIFHGPGFSALL 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           R  A R +G T+FGY V DP R+GV   D       +EEKP +P+S  AVTGLY YD+ V
Sbjct: 121 REQARRVDGCTLFGYPVRDPHRYGVAVVDSGGHLTDIEEKPDRPRSELAVTGLYMYDNDV 180

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           V  A+ ++PS RGELE+T IN+ YLE G   +  LGRGF WLDTGTH++L+EA  +V  +
Sbjct: 181 VGIARGLRPSARGELEVTDINRAYLERGKARLVQLGRGFVWLDTGTHEALLEAGQYVHIL 240

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRARPRQY 293
           E+RQ  +IACLEEIA+R G++D   ++R     A T YG YL E+    P  +
Sbjct: 241 EQRQSVRIACLEEIAFRMGFIDRAALQRLGREHADTDYGAYLTEIADKPPATW 293


>UniRef50_C7XIA2 Glucose-1-phosphate thymidylyltransferase n=1 Tax=Lactobacillus
           crispatus 125-2-CHN RepID=C7XIA2_9LACO
          Length = 270

 Score =  296 bits (757), Expect = 8e-79,   Method: Composition-based stats.
 Identities = 166/291 (57%), Positives = 209/291 (71%), Gaps = 22/291 (7%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKGIILAGGSGTRL+P+T   SKQLLP+YDKPMIYYPLS LMLAGI++ILII+TP D   
Sbjct: 1   MKGIILAGGSGTRLYPLTLVTSKQLLPVYDKPMIYYPLSTLMLAGIKDILIISTPADTPR 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F++LLGDGS+FGI+L Y  QPSPDG AQAF +G+ F+NGEP  ++LGDNIF+G GF+  L
Sbjct: 61  FEKLLGDGSQFGIKLSYKVQPSPDGWAQAFTLGKDFINGEPCAMILGDNIFYGNGFTKLL 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           +  AA                         N +AIS+EEKP+ PKSN+AVTGLYFY + V
Sbjct: 121 KQAAADAR----------------------NGKAISIEEKPEHPKSNYAVTGLYFYPAGV 158

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            E A QVKPS RGE+EITS+N MYL+ GNL V+LLGRG+AWLD GT  SL++AS +V+ V
Sbjct: 159 SEKAAQVKPSARGEIEITSLNDMYLQEGNLDVQLLGRGYAWLDAGTMQSLVDASNYVKMV 218

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRARPR 291
           E+RQG  I+  EEIA+ +GW+D + +  AA    K+ YGQ+L  +   + R
Sbjct: 219 EERQGVSISAPEEIAYIHGWIDKDKLLDAAKHYGKSPYGQHLKSVAEGKLR 269


>UniRef50_Q9ZAE7 Glucose-1-phosphate thymidylyltransferase n=12 Tax=cellular
           organisms RepID=ACBA_ACTS5
          Length = 303

 Score =  292 bits (747), Expect = 1e-77,   Method: Composition-based stats.
 Identities = 157/285 (55%), Positives = 203/285 (71%), Gaps = 1/285 (0%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+GI+LAGG+G+RL P+T  VSKQL+P+YDKPMIYYPL+ L+  GIREIL+ITT  +   
Sbjct: 1   MRGILLAGGTGSRLRPVTWAVSKQLMPVYDKPMIYYPLATLVSCGIREILVITTETEAAQ 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           FQRLLGDGS++G++LE+A Q  P G+A+AF+IGE FL G P  L+LGDN+  G  F P +
Sbjct: 61  FQRLLGDGSQWGLRLEFAVQQRPGGIAEAFLIGEEFLAGGPVALMLGDNLLHGVDFRPCV 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           +  A  T G  VFG  V DP  +GVVEFD   R +S+EEKP +P+S +AV G Y YD+ V
Sbjct: 121 QR-ARETAGGHVFGVAVADPSAYGVVEFDAAGRVLSIEEKPVRPRSPYAVPGFYLYDADV 179

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           VE A+ ++PS RGELEIT +NQ YL  G L+V LLGRG  WLDTGT    + A  +V+ +
Sbjct: 180 VETARSLRPSARGELEITEVNQAYLRRGALSVTLLGRGAVWLDTGTLADCMRAVDYVRAI 239

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLEL 285
           ++ QG KI C+EE AWR G+LD   ++  A  L  +GYGQYLL L
Sbjct: 240 DEGQGIKIGCVEEAAWRAGFLDTAQLRALAEPLMSSGYGQYLLAL 284


>UniRef50_D1Y1R8 Glucose-1-phosphate thymidylyltransferase n=1 Tax=Pyramidobacter
           piscolens W5455 RepID=D1Y1R8_9BACT
          Length = 295

 Score =  290 bits (742), Expect = 4e-77,   Method: Composition-based stats.
 Identities = 145/286 (50%), Positives = 200/286 (69%), Gaps = 2/286 (0%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           KG+ILA G GTRLHP+T  V+KQL+P+YDKPMIYY + VL+ AG+R+I+++T+  DK  F
Sbjct: 4   KGVILAAGLGTRLHPMTLAVNKQLIPVYDKPMIYYAIWVLIKAGVRDIMLVTSEVDKNSF 63

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLR 121
           +RLLGDGS FGI + Y  Q  P+GL  AF+  E F+ G+P  L+LGDNIF+G GF   L 
Sbjct: 64  ERLLGDGSRFGIHMHYTVQYVPNGLVDAFVQTEDFIAGDPCVLILGDNIFYGSGFPAMLS 123

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVV 181
             +A+ EGATVFG  V DPERFGV  F++  + ++LEEKP  PKSN AV GLYF+D KV+
Sbjct: 124 KASAQMEGATVFGANVPDPERFGVASFNEEGKVLTLEEKPVHPKSNCAVVGLYFFDGKVM 183

Query: 182 EYAKQVK--PSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           +YA +++       E+ IT +N++Y+E G L +++  +GFAWLD+GT+DSL+EAS +V  
Sbjct: 184 QYAHELRRQIPADKEVSITDVNRVYMEQGKLDLQVFPQGFAWLDSGTYDSLLEASNYVAR 243

Query: 240 VEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLEL 285
           VE+ QG  I C EE A+  G+L  E ++    +     YG+YL +L
Sbjct: 244 VEREQGHMICCPEEAAYSAGFLALEKLREYGEADKNNNYGRYLTKL 289


>UniRef50_C7IJC3 Glucose-1-phosphate thymidylyltransferase n=1 Tax=Clostridium
           papyrosolvens DSM 2782 RepID=C7IJC3_9CLOT
          Length = 285

 Score =  282 bits (722), Expect = 1e-74,   Method: Composition-based stats.
 Identities = 143/285 (50%), Positives = 194/285 (68%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK IILAGG G+R++P T  +SK L  IYDKPMIYY  S+ ++AGI E+LII   E    
Sbjct: 1   MKAIILAGGKGSRMYPATVAISKHLFLIYDKPMIYYSFSIALMAGINEVLIIAGNEHIEA 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F+ L GDGS  GI +EY  Q  P G+A+AFIIGE F+  +  CL+LGDN F+G  F   L
Sbjct: 61  FRNLFGDGSNLGIHIEYRIQDEPRGIAEAFIIGEKFIGNDSVCLILGDNFFYGDSFVYHL 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           + ++   EGA +F YQ  +PE FGVVEFD+  R +S++EK K   SN+ V G+YFYD+ V
Sbjct: 121 KALSQLKEGAGIFAYQEKNPEEFGVVEFDETGRVLSIKEKSKDSNSNYVVPGVYFYDNHV 180

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           +E AK +KPS+RGELEIT++N +YLE G L VE+L     WLDTG++++L+EAS FV++V
Sbjct: 181 IEVAKSIKPSKRGELEITTVNNVYLEKGKLKVEVLPPDVKWLDTGSYETLLEASNFVKSV 240

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLEL 285
           +   G  I+CLEEI+++N ++    V  AA     T Y +YLL +
Sbjct: 241 QTETGNMISCLEEISYKNRFIGKSEVAMAAEKYKGTQYSEYLLSI 285


>UniRef50_D0RRF5 Glucose-1-phosphate thymidylyltransferase (DTDP-glucosesynthase)
           (DTDP-glucose pyrophosphorylase) n=1 Tax=alpha
           proteobacterium HIMB114 RepID=D0RRF5_9RICK
          Length = 294

 Score =  259 bits (662), Expect = 9e-68,   Method: Composition-based stats.
 Identities = 125/287 (43%), Positives = 174/287 (60%), Gaps = 1/287 (0%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           KGIILAGG GTRL PIT+  +KQLLPIYDKP+ +YPLS+LMLA IR IL+I     K  F
Sbjct: 4   KGIILAGGKGTRLSPITKSTNKQLLPIYDKPLFFYPLSILMLADIRNILLIINKGQKKNF 63

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLR 121
             ++GDG   G+++ Y EQ  P G+ +AF IG+ F+      L+LGDN F+GQ  +  L+
Sbjct: 64  INVVGDGRHLGLKISYEEQLKPSGIPEAFKIGKKFIGNSNVSLILGDNFFYGQSLTELLQ 123

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVV 181
                 +G TVF   V  PE +GV +  D  + + + EKPK+  S+ A+TGLYF+D+ VV
Sbjct: 124 TTKVFKKGCTVFLKGVSKPENYGVAKIKDK-KIVEIIEKPKKFISDKAITGLYFFDNHVV 182

Query: 182 EYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVE 241
           + A ++KPS+R E EI  + + Y +   L    LGRG  W D G  D     S FV +VE
Sbjct: 183 QIAHKLKPSKRKETEIVDVIKNYKKRNCLNFIELGRGAIWSDAGKIDDFTNISNFVTSVE 242

Query: 242 KRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRA 288
           K QG KIACL+EIA++  W+  + + +      +  Y  YL +++  
Sbjct: 243 KVQGIKIACLDEIAYQKKWITKKQILKNIKFYGECPYSNYLRKIINN 289


>UniRef50_C7NU65 Glucose-1-phosphate thymidyltransferase n=5 Tax=Euryarchaeota
           RepID=C7NU65_HALUD
          Length = 357

 Score =  255 bits (651), Expect = 1e-66,   Method: Composition-based stats.
 Identities = 97/271 (35%), Positives = 145/271 (53%), Gaps = 3/271 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG++LAGG+G+RL PIT    KQLLP+ +KP++ Y +  L  AGI +I ++   + +  
Sbjct: 1   MKGVLLAGGTGSRLRPITHTGPKQLLPVANKPVLEYAVEDLKDAGITDIGVVLGHKGREA 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            Q LLGDGSE+G+ + Y  Q +P GLA A      F+  +   + LGDNI   QG    +
Sbjct: 61  IQELLGDGSEYGVDITYIVQGNPLGLAHAAGCARDFVGDDDFVMYLGDNIL-KQGIEDLV 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
               A   GA +   +V +P  FG+ E D +     L EKP  P SN A+ G+Y + + V
Sbjct: 120 ESFQAGEYGAGIALQEVQNPSEFGIAETDADGAVTRLVEKPADPPSNRALIGIYVFSNDV 179

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV-QT 239
            +  ++++PS RGELEIT   Q  LE GN     +  G+ W DTG    +++A+  V + 
Sbjct: 180 FDVIEELEPSWRGELEITDAIQDLLEEGNPIDSHVVEGW-WKDTGRPQDILDANRLVLED 238

Query: 240 VEKRQGFKIACLEEIAWRNGWLDDEGVKRAA 270
           V   +  +I+   E+  R        V+  A
Sbjct: 239 VADDRAGEISTDAEVTGRVDLAPSARVEAGA 269


>UniRef50_Q55689 Glucose-1-phosphate thymidylyltransferase n=52 Tax=cellular
           organisms RepID=Q55689_SYNY3
          Length = 393

 Score =  249 bits (636), Expect = 9e-65,   Method: Composition-based stats.
 Identities = 93/271 (34%), Positives = 143/271 (52%), Gaps = 4/271 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +IL+GG GTRL P+T   +KQL+P+ +KP+++Y +  +  AGI +I II +PE    
Sbjct: 29  MKALILSGGKGTRLRPLTYTGAKQLVPVANKPILWYGIEAIAKAGITDIGIIISPETGEE 88

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            + + G+G +FGIQ+ Y  Q  P GLA A      FL   P  + LGDN+         L
Sbjct: 89  IKTITGNGEKFGIQITYILQSEPLGLAHAVKTAADFLQDSPFVMYLGDNLIQDH-LEQFL 147

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
            H  A++  + +   +V +P  FGV   +D  + ++L EKP+ P SN A+ GLYF+   +
Sbjct: 148 AHFQAKSLDSLILLRRVSNPSAFGVATVNDQGKVLALVEKPEHPPSNLALVGLYFFAPTI 207

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            +    ++PS RGELEIT   Q YL + +  VE L     WLDTG  D L+ A+  +   
Sbjct: 208 HQAIANIEPSARGELEITDAIQ-YLISHDYRVESLQLKGWWLDTGKKDDLLAANQIILDT 266

Query: 241 EKRQGFKIACLE--EIAWRNGWLDDEGVKRA 269
              +  +    +  +I+ R        +  +
Sbjct: 267 LVEKNIQGTVDDQSKISGRVTIGPHSQIINS 297


>UniRef50_A7HN10 Glucose-1-phosphate thymidyltransferase n=9 Tax=cellular organisms
           RepID=A7HN10_FERNB
          Length = 376

 Score =  241 bits (615), Expect = 2e-62,   Method: Composition-based stats.
 Identities = 90/238 (37%), Positives = 131/238 (55%), Gaps = 4/238 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK IIL  G GTRL P+T   +K L+P+ +KP+I Y +  +   GI++I II +PE+K  
Sbjct: 18  MKAIILCAGKGTRLRPLTYTTAKHLIPVANKPVILYTIEKIKSVGIKQIGIIVSPENKAD 77

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F+  LGDGS++G+++ Y  QP P GLA A ++ + FL  E   + LGDN+       P +
Sbjct: 78  FEENLGDGSKYGVEITYILQPEPKGLAHAVLMAKDFLGDEDFMMYLGDNLIMD-DIRPFV 136

Query: 121 RHVAARTE-GATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSK 179
                R    A +    V DP RFG+   + N R +   EKPK+P SN A+ GLY +   
Sbjct: 137 DEFEQRKNISALIMLSPVNDPTRFGIAVMEGN-RIVKTVEKPKEPPSNLAIIGLYLFRKD 195

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
           + E    +KPS RGELEIT      ++        +  G+ W DTG  + L+EA+  +
Sbjct: 196 IFEGIANIKPSWRGELEITDAIDWLIQNKGNVEGHIIYGW-WKDTGKPEDLLEANHKI 252


>UniRef50_Q46AY8 Glucose-1-phosphate thymidylyltransferase n=4
           Tax=Methanosarcinaceae RepID=Q46AY8_METBF
          Length = 397

 Score =  240 bits (612), Expect = 5e-62,   Method: Composition-based stats.
 Identities = 78/281 (27%), Positives = 138/281 (49%), Gaps = 18/281 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++L  G GTR+ P+T G  K +L + +KP++ + L+  + AGI   + IT    +  
Sbjct: 1   MKAVVLVAGKGTRMEPLTSGCPKVMLQVANKPILEHILNSAIEAGIEGFVFITGY-LEKQ 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDG+++G+ +EY +Q    G A A    + +++G  + LVL  ++   Q     L
Sbjct: 60  IKEYFGDGNKWGVSIEYVQQKEQLGTANAIGCAKGYVDG--TFLVLNGDMLIEQ---EDL 114

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           + + +RTE A +   +V +P  FGV+E  +N R + + EKPK P +N A  G+Y +   +
Sbjct: 115 KALVSRTEEAVICVKEVENPADFGVLET-ENNRVVRIIEKPKNPPTNLANAGIYLFRESI 173

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            ++  + K S R E EIT   QM +++G   V        W+D G    L++A+ ++   
Sbjct: 174 FDFIDRTKASVRNEFEITDSIQMLIDSGT-AVGYSPLEGRWIDIGYPWDLLKANEYLL-- 230

Query: 241 EKRQGFKIACLEEIAWRNGW-----LDDEGVKRAASSLAKT 276
              +G K +C   +           +    + R  S +   
Sbjct: 231 ---KGLKSSCEGTVEPNATIKGEVVIGKGTIIRNGSYIEGP 268


>UniRef50_A3DED2 Nucleotidyl transferase n=8 Tax=Clostridium RepID=A3DED2_CLOTH
          Length = 820

 Score =  239 bits (610), Expect = 9e-62,   Method: Composition-based stats.
 Identities = 63/239 (26%), Positives = 108/239 (45%), Gaps = 10/239 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +I+AGG GTRL P+T    K ++P+ +KP++ + + +L   G  +I  +T       
Sbjct: 1   MKAVIMAGGEGTRLRPLTCNRPKPMVPVVNKPVMEHIIELLKKHGFTDIA-VTLQYLPDM 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDGS+FGI L Y  +  P G A +    E FL  + + LV+  +          +
Sbjct: 60  IKDYFGDGSDFGINLRYYVEDKPMGTAGSVKNAEEFL--DDTFLVISGDALTDIDLGKAV 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
            +  ++   AT+   +V  P  +GVV  D+N R     EKP   +  S+   TG+Y    
Sbjct: 118 EYHYSKGSMATLVLKKVDIPLEYGVVVTDENGRITRFLEKPSWGEVFSDTVNTGIYILSP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
           +V++Y  + +  +        +  M L+        +   + W D G   +  +A   V
Sbjct: 178 EVLKYFNKNEMFDF----SKDLFPMLLKENKPMYGYITDEY-WCDIGDLMAYSKAHMDV 231


>UniRef50_UPI0001C418F3 UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate
           N-acetyltransferase GlmU n=1 Tax=Methanobrevibacter
           ruminantium M1 RepID=UPI0001C418F3
          Length = 439

 Score =  237 bits (605), Expect = 3e-61,   Method: Composition-based stats.
 Identities = 81/283 (28%), Positives = 133/283 (46%), Gaps = 12/283 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +IL+ G GTR+ P+T    K +LP+  KP+I Y +  L   G+++IL+I   + +  
Sbjct: 1   MKALILSAGEGTRMRPLTLTKPKTMLPVAGKPIIQYNIEALRECGVKDILLIVGYK-EEM 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQG-FSPK 119
            +    DGS+FG+ + YA Q   +G A A   G+ F+  E S + L  +I   +      
Sbjct: 60  VKNYFDDGSKFGVNISYATQTKLEGTANAISYGKDFI--EDSLITLNGDIILDEEILREI 117

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYD 177
           +           +   +V DP  FGVVE D   +  ++ EKP  ++  SN   TG+Y ++
Sbjct: 118 IEDYEESGADTLMVLTEVEDPSAFGVVELDGE-KITNIVEKPKKEEAPSNLVNTGIYIFN 176

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
             + +   + K S RGE EIT    + +E G            W+D G    LIE +  +
Sbjct: 177 KDIFDKIDKTKVSPRGEYEITDSLSLQIEDGKFVKGH-KTEKEWMDIGKPWELIEINESL 235

Query: 238 QTVEKRQGFKIACLEEIAWRNG--WLDDEGVKRAASSLAKTGY 278
             +   +G     +EE A  +G  +LD+  + R+   +    Y
Sbjct: 236 --LNNIKGEIKGTVEEGATLHGEVFLDEGSLIRSGVYIKGPVY 276


>UniRef50_C8W233 Nucleotidyl transferase n=1 Tax=Desulfotomaculum acetoxidans DSM
           771 RepID=C8W233_DESAS
          Length = 830

 Score =  235 bits (600), Expect = 1e-60,   Method: Composition-based stats.
 Identities = 68/279 (24%), Positives = 124/279 (44%), Gaps = 16/279 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK II+AGG G+RL P+T G  K ++P+ +KP++ + + +L   GI +I +      +  
Sbjct: 3   MKAIIMAGGEGSRLRPLTCGRPKPMVPVLNKPVMCHIIDLLKQHGITDIGVTLQYMPEA- 61

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   G GS+FG+ + Y  + SP G A +      FL  + + LV+  +       S  +
Sbjct: 62  IKDYFGSGSQFGVNISYFVEESPLGTAGSVKNAGNFL--DETFLVISGDALTDLNLSKAI 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
                +   AT+   +V  P  +GVV  ++N R     EKP   +  S+   TG+Y  + 
Sbjct: 120 EFHRNQCSDATILLTRVDCPLEYGVVITEENGRIRRFLEKPSWGEVFSDTVNTGIYILEP 179

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
            V++Y  Q +  +        +    L+       L+ +G+ W D G     ++A     
Sbjct: 180 GVLDYFNQGQVFDF----SKDLFPRLLKDKKPLFGLVQQGY-WCDIGNLRQYLQAHYDAL 234

Query: 239 TVEKRQGFKIACL-EEIAWRNGWLDDEGVKRAASSLAKT 276
           + +     KI+   +EIA +  W+    +   +  +   
Sbjct: 235 SGK----VKISIPGKEIA-QGVWVGKGALISDSVEMEGP 268


>UniRef50_P39629 Spore coat polysaccharide biosynthesis protein spsI n=88
           Tax=cellular organisms RepID=SPSI_BACSU
          Length = 246

 Score =  235 bits (600), Expect = 1e-60,   Method: Composition-based stats.
 Identities = 106/244 (43%), Positives = 151/244 (61%), Gaps = 4/244 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+ILAGG+G+RL P+T+ V+K LLP+   PMIY+ +  L  AGI++IL+I+  E    
Sbjct: 1   MKGVILAGGNGSRLMPLTKAVNKHLLPVGPYPMIYWSIMKLQEAGIKDILLISQKEHMPQ 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F +LLG+G E G+ + Y  QP+  G++      + F   E   L+LGDNIF      P  
Sbjct: 61  FYKLLGNGEELGVTITYQVQPAASGISDGLSYAKRFTKKESFILLLGDNIFED-SLKPYT 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDD-NFRAISLEEKPKQPKSNWAVTGLYFYDSK 179
                + +GA V   +V DPERFG+ E D+ N R  S+ EKP+QP +N  VTG+Y YD++
Sbjct: 120 ERFEQQGKGAKVLLKEVDDPERFGIAEIDEKNKRIRSIIEKPEQPPTNLCVTGIYMYDAE 179

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           V  Y +Q+ PS+RGELEIT +N +Y+E   LT ++L     W+D GTH+SL  AS  V  
Sbjct: 180 VFSYIEQISPSKRGELEITDVNNLYIENSQLTYDVL--SGWWVDAGTHESLYLASQLVHQ 237

Query: 240 VEKR 243
             ++
Sbjct: 238 ALRK 241


>UniRef50_A5D3D6 dTDP-glucose pyrophosphorylase n=5 Tax=Bacteria RepID=A5D3D6_PELTS
          Length = 388

 Score =  235 bits (599), Expect = 2e-60,   Method: Composition-based stats.
 Identities = 90/252 (35%), Positives = 132/252 (52%), Gaps = 2/252 (0%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +K +IL+GG GTRL P+T   +KQL+P+ +KP++ + +  +  AGIR+I +I +PE    
Sbjct: 34  VKALILSGGKGTRLRPLTYTTAKQLIPVANKPILEFVVEQICQAGIRDIGMIISPETGEQ 93

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  +G G  +G ++ Y  Q  P GLA A      FL   P  + LGDN+  G G    +
Sbjct: 94  VKEAIGCGERWGARITYILQEKPAGLAHAVKTARPFLGDSPFLMFLGDNLVQG-GVGQLV 152

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           +  A     A +   +V DP +FGV    +N R I L EKPK+P  N A+ G+Y + S V
Sbjct: 153 KDFAGSRADAMIQLKEVADPSQFGVAVLGENNRVIRLVEKPKEPPGNLALVGIYLFGSAV 212

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
               +++KPS RGELEIT   Q  +  G      +  G+ WLDTG  D ++EA+  V   
Sbjct: 213 HRAIERIKPSWRGELEITDAIQEMINLGCSVDARILDGW-WLDTGKKDDILEANRVVLDE 271

Query: 241 EKRQGFKIACLE 252
             R         
Sbjct: 272 YARLEISGTVDR 283


>UniRef50_Q2NES5 Predicted nucleoside-diphosphate-sugar pyrophosphorylase n=10
           Tax=cellular organisms RepID=Q2NES5_METST
          Length = 431

 Score =  234 bits (596), Expect = 3e-60,   Method: Composition-based stats.
 Identities = 74/283 (26%), Positives = 124/283 (43%), Gaps = 13/283 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK IIL  G GTR+ P+T    K +L    KP+I Y +  L  AGI++I ++   + K  
Sbjct: 1   MKAIILTAGEGTRMRPLTTTRPKTMLITGGKPLIQYNIESLRDAGIKDITLVVGYK-KEV 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGF-SPK 119
            +   GDGSE+G+ + YA Q    G A A    E ++  + S +VL  +I          
Sbjct: 60  IEDYFGDGSEYGVNITYAVQEGQLGTAHAIGSAEEYI--DESFIVLNGDIIVSYDLIRNL 117

Query: 120 LRHVAARTEG---ATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLY 174
           +   A RT     + +   +V DP  +G+V   +N +   + EKP  +   SN A  G+Y
Sbjct: 118 IEKYATRTSNNVKSVLTLIEVDDPSSYGIVST-ENGKITEIIEKPSVEDAPSNLANAGIY 176

Query: 175 FYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
            +  ++ +  ++ + S+RGE EIT    + L  G   + L+     W+D G    L+E +
Sbjct: 177 LFSPEIFDAIRKTELSKRGEYEITDSLDIELSEGWEILGLISNE-KWMDVGRPWELLECN 235

Query: 235 TFVQTVEKRQGFKIACLEEIAWRNGW-LDDEGVKRAASSLAKT 276
                       +    + +       L    + R+   +   
Sbjct: 236 QDFLEKMDD-SIEGEIEDNVTIHGPVHLGKGSIIRSGCYIQGP 277


>UniRef50_Q9X3S7 Glucose-1-phosphate thymidyl transferase n=1 Tax=Neisseria
           meningitidis RepID=Q9X3S7_NEIME
          Length = 298

 Score =  233 bits (594), Expect = 6e-60,   Method: Composition-based stats.
 Identities = 134/175 (76%), Positives = 155/175 (88%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKGIILAGGSGTRL+PITRGVSKQLLP+YDKPMIYYPLSVLMLAGIR+IL+IT PED   
Sbjct: 14  MKGIILAGGSGTRLYPITRGVSKQLLPVYDKPMIYYPLSVLMLAGIRDILVITAPEDNAS 73

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F+RLLGDGS+FGI + YA QPSPDGLAQAFIIGE F+  +  CLVLGDNIF+GQ F+  L
Sbjct: 74  FKRLLGDGSDFGISISYAVQPSPDGLAQAFIIGEEFIGNDNVCLVLGDNIFYGQSFTQTL 133

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYF 175
           +  AA+T GATVF YQV +PERFGVVEF++NFRA+S+EEKP++PKS+WAVTGLYF
Sbjct: 134 KQAAAQTHGATVFAYQVKNPERFGVVEFNENFRAVSIEEKPQRPKSDWAVTGLYF 188


>UniRef50_B5YF33 Mannose-1-phosphate guanyltransferase n=2 Tax=Dictyoglomus
           RepID=B5YF33_DICT6
          Length = 827

 Score =  232 bits (592), Expect = 1e-59,   Method: Composition-based stats.
 Identities = 67/279 (24%), Positives = 119/279 (42%), Gaps = 14/279 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +I+AGG GTRL P+T    K +  I  KP++ + +++L   G RE L  T       
Sbjct: 1   MRAVIMAGGEGTRLRPLTLTRPKPMTYIVGKPIMEHIINLLSEQGFRE-LTATLYYLPEI 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            Q    DGS + + L+Y+ + SP G A +          +   L++  +          +
Sbjct: 60  IQEYFDDGSNWNVNLDYSIEESPLGTAGSVKYALKNKPKDR-ILIISGDALTDFNLREAI 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
           +         T+    V +P  +GVV   ++ + I   EKP   +  S+   TG+Y  + 
Sbjct: 119 KFHEENGALVTIVLTSVENPLEYGVVITKEDGKIIKFLEKPSWGEVFSDSVNTGIYILEP 178

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +V++Y    +P +        +  M LE        L +G+ W D G  +  ++A+    
Sbjct: 179 EVLDYIPDNQPFDF----SKDLFPMLLEKNAPLYGYLAQGY-WCDIGNLEQFLQAN--FD 231

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTG 277
            + K+   KI   E +    G   +E V+ A S+  +  
Sbjct: 232 ALNKKVKIKIPGREILP---GIYTNEEVEIATSAFIRPP 267


>UniRef50_UPI0001C42A13 Nucleoside-diphosphate-sugar pyrophosphorylase fused to
           phosphomannomutase n=1 Tax=Bacillus pseudofirmus OF4
           RepID=UPI0001C42A13
          Length = 808

 Score =  231 bits (589), Expect = 2e-59,   Method: Composition-based stats.
 Identities = 70/275 (25%), Positives = 115/275 (41%), Gaps = 10/275 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+I+AGG GTRL P+T  + K ++P+  KP++ Y + +L   GI +I  +T       
Sbjct: 1   MKGVIMAGGKGTRLRPLTCQLPKPMVPLLQKPVMQYSIELLKQHGITDIA-VTVHYLPDE 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDG EFG+ L Y E+  P G A +    E FL  +   +V+  +          +
Sbjct: 60  IRDYFGDGQEFGVHLTYFEETEPLGTAGSVKQAEAFL--DEPFVVVSGDALTDFDLEAGI 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDS 178
               A+    ++F  QV  P  FGV+  +     I   EKP   +  S+   TG+Y  D 
Sbjct: 118 NFHKAKDALVSIFMKQVPCPLEFGVIMTNQQHEIIRFLEKPSVSEVFSDTVNTGIYVMDP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
            +  Y +  KP +        +    LE           G+ W D G  +   +A   + 
Sbjct: 178 SIFNYIESDKPVDF----SKDVFPRILEDRAGIYGYAAEGY-WSDIGNLEQYRQAHMDLL 232

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSL 273
             + +       +E   W N  +  E   +  + +
Sbjct: 233 NRDVKAEISGIEVEPGIWMNEHVTIEEGVKLEAPV 267


>UniRef50_C0ZG53 Probable mannose-1-phosphate guanyltransferase n=1
           Tax=Brevibacillus brevis NBRC 100599 RepID=C0ZG53_BREBN
          Length = 801

 Score =  230 bits (587), Expect = 4e-59,   Method: Composition-based stats.
 Identities = 73/280 (26%), Positives = 121/280 (43%), Gaps = 14/280 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +I+AGG GTRL P+T    K ++P+ ++P + Y + +L   GI EI  +T       
Sbjct: 1   MKAVIMAGGKGTRLRPLTCHTPKPMVPLLNRPCMEYTIDLLKKHGITEIA-VTLQYLPDV 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDGS +G+ L Y E+  P G A +      FL  +   +V+  +       S  +
Sbjct: 60  IRDTFGDGSRYGVSLVYFEEAIPLGTAGSVKNCADFL--DERFVVISGDTLTDIDLSAAI 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPK--SNWAVTGLYFYDS 178
           R        AT+   +V  P  FGVV  D+  R     EKP   +  S+   TG+Y  + 
Sbjct: 118 RFHEQNNALATLILTRVETPLEFGVVMTDEGGRITRFLEKPSWAEVFSDTVNTGIYVCEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +V+ Y ++    ER       I   +L+A          G+ W D G+ +   +A     
Sbjct: 178 EVLSYIEE----EREVDFSKEIFPSFLQAAKPLYGYEASGY-WSDIGSLEVYQQA--QFD 230

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
            ++ R   +I   E       +L+++    ++  L    Y
Sbjct: 231 LLDGRVHLEIKAQEIAP--RIFLENDVRIDSSVRLEGPVY 268


>UniRef50_A5N939 Predicted glucose-1-phosphate nucleotidyltransferase containing an
           additional conserved domain n=5 Tax=Clostridium
           RepID=A5N939_CLOK5
          Length = 814

 Score =  230 bits (587), Expect = 4e-59,   Method: Composition-based stats.
 Identities = 62/236 (26%), Positives = 107/236 (45%), Gaps = 10/236 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +I+AGG GTRL P+T  + K ++P+  KP++ Y L +L   GI +I   T       
Sbjct: 1   MKAVIMAGGEGTRLRPLTCNIPKPMMPVMGKPIMEYALELLKNTGIEDIG-ATLQYLPDE 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                GDG +FG+ + Y  + +P G A +    E FLN   + +V+  +       S  +
Sbjct: 60  IINYFGDGRDFGVNISYFVEETPLGTAGSVKNAEAFLND--TFIVISGDALTDIDLSRAI 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDS 178
            +  ++   AT+   +   P  FGVV  DD  +     EKP   +  S+   TG+Y  + 
Sbjct: 118 SYHKSKGAVATLVLKEEPVPLEFGVVVTDDKGKVTGFLEKPGWGEVFSDKVNTGIYILEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
           ++ +Y  + K  +      + +  + L+        +  G+ W D G  D  ++  
Sbjct: 178 EIFKYYGKNKKCDF----SSELFPLLLKEKAAVFGYVAEGY-WCDIGNIDQYMKCH 228


>UniRef50_Q3A0B4 Mannose-1-phosphate guanyltransferase n=10 Tax=Desulfuromonadales
           RepID=Q3A0B4_PELCD
          Length = 842

 Score =  229 bits (583), Expect = 1e-58,   Method: Composition-based stats.
 Identities = 63/238 (26%), Positives = 107/238 (44%), Gaps = 10/238 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +I+AGG GTR+ P+T  + K ++P+ ++P++ + + +L   GI +++++   + +  
Sbjct: 1   MKAVIMAGGFGTRMQPLTINLPKPMVPLVNQPIMSHIIDLLKAHGISDVIMLLFHQPE-I 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDGSE G+++ Y       G A A      +L  +   LV+  ++         L
Sbjct: 60  IKNYFGDGSELGVRITYVTPLEDFGTAGAVKAAAPYL--DERFLVISGDLLTDFDLGAVL 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDS 178
                +   AT+    V DP +FGVV  D         EKP   +  S+   TG+Y  + 
Sbjct: 118 SFHEEKQALATITLTSVEDPLQFGVVITDQQGAITKFLEKPGWGEVFSDTINTGIYVLEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTF 236
           +V+E      P E        I    LE G      L +G+ W D G  D+ +E    
Sbjct: 178 EVLEMI----PEETNRDWSKDIFPRMLEEGRPLYGCLQQGY-WADIGNTDAYLETCRD 230


>UniRef50_C9RWA3 Nucleotidyl transferase n=7 Tax=Geobacillus RepID=C9RWA3_GEOSY
          Length = 347

 Score =  229 bits (583), Expect = 1e-58,   Method: Composition-based stats.
 Identities = 66/236 (27%), Positives = 104/236 (44%), Gaps = 10/236 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++LAGG GTRL P+T  + K + PI ++P + + +  L   G+ E  +I        
Sbjct: 1   MKALLLAGGLGTRLRPLTENIPKPMAPIANRPWLEHLIVHLRDQGVNEF-VIAAHHCSEV 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +R   DG  + +++ YA +P P G A A    E +L      LV   +I       P L
Sbjct: 60  IRRYFEDGKRWNVKITYALEPFPLGTAGAIKNAERWLK--ERFLVFNADIVHLPQLIPLL 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDS 178
                    AT+   +V DP  +GVVE DD  + +   EKP  ++  SN    G+Y ++ 
Sbjct: 118 DFHRQHGGLATIVLTEVDDPSSYGVVEQDDRGQILRFVEKPRREEAPSNRINAGMYIFEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
            V+ Y     P+ER          + +E       ++  G+ W D GT     +  
Sbjct: 178 DVMRYI----PAEREVSIERETFPLLIEKNVGVYGIVSNGY-WRDMGTPARYRQVH 228


>UniRef50_A4J6Z1 Nucleotidyl transferase n=3 Tax=Peptococcaceae RepID=A4J6Z1_DESRM
          Length = 828

 Score =  228 bits (582), Expect = 1e-58,   Method: Composition-based stats.
 Identities = 60/279 (21%), Positives = 118/279 (42%), Gaps = 14/279 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK II+AGG GTRL P+T G+ K ++P+ ++PM+ + L +L   G+ +I +      +  
Sbjct: 7   MKAIIMAGGEGTRLRPLTCGLPKPMMPVCNRPMMEHILHLLKKHGVHDIGVTLQYLPEA- 65

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   G+G++F + + Y  +  P G A +    + FL  + + +V+  +       S  L
Sbjct: 66  IRGYFGNGADFNVHMRYYVEEVPLGTAGSVKNAQKFL--DETFIVISGDALTDLDLSQAL 123

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDS 178
                +   AT+    V  P  +GVV  + +       EKP   +  S+   TG+Y  + 
Sbjct: 124 EFHRKKGAIATLVLTPVDIPLEYGVVITNGDGHITQFLEKPGWGEVFSDTVNTGIYILEP 183

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +V+ Y +  +  +        +  + L+       +   G+ W D G     ++A     
Sbjct: 184 EVLNYFEPGQKFDF----SNDLFPILLKEKQPLFGVSLSGY-WCDIGNLQQYVQAHQDCL 238

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTG 277
           T +      ++   E      W+ +    +A + +    
Sbjct: 239 TGK----VSVSIPGEQVAPGVWVGENTQIQAGAKIIGPA 273


>UniRef50_B5GLJ2 NDP-1-glucose synthase n=1 Tax=Streptomyces clavuligerus ATCC 27064
           RepID=B5GLJ2_STRCL
          Length = 359

 Score =  228 bits (582), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 91/242 (37%), Positives = 126/242 (52%), Gaps = 3/242 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++LAGGSG+RL P++  + KQL+P+ +KP++ Y L  +   GI  I ++        
Sbjct: 1   MKALVLAGGSGSRLRPLSNFMPKQLIPVANKPVLEYVLENIRELGITRIGLVVG-GWADT 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  +GDGS FG ++ Y  Q  P GLA A  +   FL  +   + LGDN+    G +P  
Sbjct: 60  IRGAVGDGSRFGAEITYLRQERPAGLAHAVRLARPFLGDDDFAMFLGDNLLPD-GVAPVA 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                    A V  ++V DP  FGVVE D       L EKP +P+S+ A+ G YF+ S V
Sbjct: 119 ADFLRGRPAAQVVVHKVDDPRDFGVVELDAAGGVRRLVEKPSRPRSDLALVGTYFFTSAV 178

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
                 ++PS RGELEIT   Q  LE G  +V     G  W DTG  D L+EA+  V   
Sbjct: 179 HRAVDAIRPSPRGELEITDAIQWLLEDG-ASVGCSEYGGYWKDTGRADDLLEANRRVLEG 237

Query: 241 EK 242
           E 
Sbjct: 238 ES 239


>UniRef50_Q97A91 Glucose-1-phosphate thymidylyltransferase n=2 Tax=Thermoplasma
           volcanium RepID=Q97A91_THEVO
          Length = 351

 Score =  228 bits (582), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 90/280 (32%), Positives = 133/280 (47%), Gaps = 7/280 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKGIIL GGSGTRL P+T    KQLLPI  KP+  Y L  L+  GI+ I I+        
Sbjct: 3   MKGIILHGGSGTRLRPLTYTDVKQLLPIAGKPISEYALENLIEIGIKNINIVIGSVGGLE 62

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            ++  GDGS + + + Y  QP P G+A A  + + F+  +   + LGDN +   G S   
Sbjct: 63  VKKFYGDGSRWNVNISYTYQPEPLGIAHAIGLTKAFVGNDDFVVFLGDN-YLQNGISNLY 121

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                      +    V +P +FG+ E D N +   L EKPK P SN A+ G+YF   KV
Sbjct: 122 EDFTNAGSDGHLGLVPVDNPSQFGIAEVD-NGKISKLVEKPKTPTSNLAIVGVYFLTPKV 180

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            E   ++KPS+RGE EIT   Q  ++ G      +  G+ + DTGT D  +  +  +   
Sbjct: 181 FESIDRLKPSKRGEYEITEAYQDMIDRGLKISYSIISGW-FKDTGTVDDFLACNRLILDK 239

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQ 280
               G +    + ++ R        +   +  +     G+
Sbjct: 240 LGDNGRR----DNVSGRFDIHPTVKISSDSEVVGPCFIGE 275


>UniRef50_C0ZCI7 Probable glucose-1-phosphate thymidylyltransferase n=1
           Tax=Brevibacillus brevis NBRC 100599 RepID=C0ZCI7_BREBN
          Length = 348

 Score =  228 bits (582), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 87/249 (34%), Positives = 129/249 (51%), Gaps = 4/249 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+IL  G GTRLHP +    K LLP+ + P+++Y +  L   GI++I I+  P  +  
Sbjct: 1   MKGLILCAGRGTRLHPFSYSQPKTLLPVANHPVLHYCIRKLREVGIQDIGIVIHP-SQSQ 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
              ++GDGS+FG  + + +Q  P G+A A  + + FL  EP  L+LGDN+          
Sbjct: 60  IPPMVGDGSQFGATITFIKQEVPLGIAHAVQLAQPFLQDEPFILLLGDNLLMD-SLHGLT 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           +          V   +V  P+ +G+ E     R IS+EEKP+QPKSN AV G Y +   +
Sbjct: 119 KAFTKGKSDGVVMLSKVERPQDYGIAEVQK-GRLISVEEKPRQPKSNLAVIGAYLFTPPI 177

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            E    ++PS RGELEIT   Q  +  G      +  G  + D GT D  +EA+ ++ T 
Sbjct: 178 FESIATLQPSPRGELEITDAIQSMINRGFKLAHSVTNG-KYSDVGTIDRWLEANQWMLTR 236

Query: 241 EKRQGFKIA 249
           E     +I 
Sbjct: 237 ELGNQHQIG 245


>UniRef50_UPI000038E60D glucose-1-phosphate thymidylyltransferase (graD-2) n=1
           Tax=Ferroplasma acidarmanus fer1 RepID=UPI000038E60D
          Length = 351

 Score =  228 bits (581), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 96/277 (34%), Positives = 146/277 (52%), Gaps = 4/277 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKGIIL GG+GTRL P+T    KQL+PI +KPM  Y L  L  AGI +I +I        
Sbjct: 1   MKGIILHGGAGTRLRPLTHTGPKQLIPIANKPMSQYVLEYLTDAGINDICMILGDISPEK 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDGSEF   ++Y +Q +P G+A A  +   F+  +   ++LGDN+  G+     +
Sbjct: 61  VKDYYGDGSEFDCNIQYIDQGAPLGIANAVSLTSNFVGNDKFVVILGDNLIEGK-IKTFM 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                    A +   + M P+ FGV EF DN + I+L EKP+ P SN+ +TG+YF+   +
Sbjct: 120 DKFEKSNYDAFIVLTKSMHPKDFGVAEFRDN-KLINLIEKPENPPSNYVLTGIYFFTPLI 178

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            +Y K++KPS R E EIT   Q+ L+        +  G+ W DTGT D ++ A+  +   
Sbjct: 179 FDYIKKLKPSWRNEYEITEAIQLLLKDNKNIGYDIIDGW-WKDTGTVDDILAANMLILDR 237

Query: 241 EKRQGFKIACLEEIA-WRNGWLDDEGVKRAASSLAKT 276
            K    +     ++A  +N  L D+ + R  + +   
Sbjct: 238 GKNIEERANVKGKVAIGKNVVLSDDSLIRGPAIIGDN 274


>UniRef50_C7LZ98 Nucleotidyl transferase n=1 Tax=Acidimicrobium ferrooxidans DSM
           10331 RepID=C7LZ98_ACIFD
          Length = 854

 Score =  228 bits (581), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 70/258 (27%), Positives = 114/258 (44%), Gaps = 12/258 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +I+AGG GTRL P+T    K LLP+ ++PMI   + +L+  GI +I I+T       
Sbjct: 1   MQAVIIAGGEGTRLRPLTSTTPKPLLPVANRPMIARVVDLLVANGIDDI-IVTVAYLGSA 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  LGDG+++G ++ Y ++ SP G A A       L  E + +VL  ++          
Sbjct: 60  IRTYLGDGTDWGARIRYLQEESPLGTAGAVRNARHLL--EDTFIVLSGDVVTTVDLEAAR 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
           R    R   AT+    V DP  FGVV  +D+     L EKP   +  ++   TG+Y  + 
Sbjct: 118 RFHHERGASATMVLTTVPDPTEFGVVATEDSGAVTRLIEKPSWGEVFTDTVNTGVYILEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
            V++     +  +  E     +    L+        +  G+ W D GT     +    V 
Sbjct: 178 SVLDRIPANRAVDFSE----EVFPQILDDRGALFGYVADGY-WADVGTFSGFHQTHHDV- 231

Query: 239 TVEKRQGFKIACLEEIAW 256
            ++ R G   +  E    
Sbjct: 232 -LDGRAGIAPSGFELAPG 248


>UniRef50_Q01T68 Nucleotidyl transferase n=8 Tax=cellular organisms
           RepID=Q01T68_SOLUE
          Length = 257

 Score =  228 bits (581), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 113/257 (43%), Positives = 154/257 (59%), Gaps = 8/257 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG++LAGG+G+RL P+T+  +K LLPIYD+PMIYYP+  L+ AGI+EILI+T   + G 
Sbjct: 1   MKGVVLAGGTGSRLFPLTKITNKHLLPIYDRPMIYYPIQTLVDAGIQEILIVTGGRNSGD 60

Query: 61  FQRLLGDGSEFGIQ-LEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK 119
           F RLL +G +FG++ + Y  Q    G+A A  + E F +G   C+VLGDNI  G      
Sbjct: 61  FLRLLANGKQFGLKHINYTYQEGEGGIADALALAEHFADGHQICVVLGDNIIEG-NIKAA 119

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSK 179
                A+  GA +   +V D ERFGV E   + R + +EEKP  PKSN+AVTG+Y YD+ 
Sbjct: 120 ADRFRAQPAGAHILLKEVQDAERFGVAEVAGD-RIVGIEEKPNNPKSNYAVTGIYMYDAS 178

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           V +  K + PS RGELEIT +N  Y+  GN++   L     W D GT DSL+ A+  V  
Sbjct: 179 VFQKIKTLVPSGRGELEITDVNNAYIREGNMSFSYL--DGWWTDAGTFDSLLRATNLVAQ 236

Query: 240 VEKRQGFKIACLEEIAW 256
              +    +A  E  A 
Sbjct: 237 SAAKT---VAVPEFAAE 250


>UniRef50_O29921 Glucose-1-phosphate thymidylyltransferase (GraD-2) n=1
           Tax=Archaeoglobus fulgidus RepID=O29921_ARCFU
          Length = 352

 Score =  228 bits (581), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 88/251 (35%), Positives = 133/251 (52%), Gaps = 3/251 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG++L GG+GTRL P+T    KQL+P+ +KP+  Y L  ++ AGI+E+ II        
Sbjct: 1   MKGVLLHGGAGTRLRPLTFTGPKQLIPVANKPVSQYCLEDMIGAGIKEVAIILGETYPEM 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDGS FG ++ Y  Q  P G+A A  + + F+  E   + LGDN+    G    +
Sbjct: 61  VEEHYGDGSRFGCKITYIHQGKPLGIAHAVYLAKDFVGDEKFVVYLGDNLI-QDGIKEYV 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           +        A +   +V DP  FGV +F+   R + L EKPK+P SN+AV G+Y +   V
Sbjct: 120 KRFDEEDFDAFILLKEVEDPRAFGVAKFEGE-RLVGLIEKPKEPPSNYAVIGVYMFKPVV 178

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            +  K +KPS RGELEIT   Q  +E G        +G+ W DTG  + +++ +  +   
Sbjct: 179 FDIIKDLKPSWRGELEITDTLQKMIENGYNVGYAKLKGW-WFDTGKAEDILKVNATILDE 237

Query: 241 EKRQGFKIACL 251
             ++  K   L
Sbjct: 238 RAKRSVKGEVL 248


>UniRef50_Q8TWY9 Nucleoside-diphosphate-sugar pyrophosphorylase involved in
           lipopolysaccharide biosynthesis; translation initiation
           factor eIF2B subunit n=1 Tax=Methanopyrus kandleri
           RepID=Q8TWY9_METKA
          Length = 425

 Score =  227 bits (580), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 70/282 (24%), Positives = 128/282 (45%), Gaps = 10/282 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M GI+LA G GTR+ P+T+   K LLP+ D+ +I + +  +   G+  ++++        
Sbjct: 1   MIGIVLAAGEGTRMRPLTKTRPKVLLPVADRRLIDFSIEAMKRIGVEHLVVVVEY-LAEK 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +R + D      +LE+  Q  P G A A  +    +  + + ++   ++ F        
Sbjct: 60  VERYVKDRWGDSFELEFVRQGKPLGTAHAVYVAWREIEPDETVVITNGDLVFDSELLE-- 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEE--KPKQPKSNWAVTGLYFYDS 178
           R V      A++   +V DP  FGV    D +  + L E  KP++  SN A  G+Y  + 
Sbjct: 118 RAVREHEGVASMVLVEVEDPSEFGVARLQDGY-VVELVEKPKPEEAPSNLANAGVYVAEP 176

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTF-V 237
           +   + ++VKPS RGE EIT    +   A +  V  +     W D G    L++A+ + +
Sbjct: 177 EFERFLERVKPSPRGEFEITDA--LLDAAIDEGVLGISYDGFWSDVGRPWDLLDANAWAL 234

Query: 238 QTVEKRQGFKIACLEEIAWRNG-WLDDEGVKRAASSLAKTGY 278
           +    R   +    E +  R   W+ ++ + R+ + +    Y
Sbjct: 235 RNAMSRPEVEGVIEENVELRGPVWVAEDAILRSGAVVEGPAY 276


>UniRef50_A7GF11 Glucose-1-phosphate thymidylyltransferase n=9 Tax=Clostridium
           botulinum RepID=A7GF11_CLOBL
          Length = 353

 Score =  227 bits (580), Expect = 3e-58,   Method: Composition-based stats.
 Identities = 83/237 (35%), Positives = 137/237 (57%), Gaps = 4/237 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +IL+GG+GTRL P+T   +KQLLP+ +KP+++Y +  ++ AGI +I II   + +  
Sbjct: 1   MKALILSGGTGTRLRPLTYTNAKQLLPLANKPILFYIIEKIVKAGIYDIGIIVG-DTREE 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            ++++G+G  +G+++ Y  QP+P GLA A      FL  +   +VLGDN+F     +  +
Sbjct: 60  VKKMVGNGDRWGVKISYLYQPAPLGLAHAVKTASEFLMEDDFLMVLGDNVF-NMELNKLI 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
               +    + +  ++V +P ++GV   +D    I L EKPK+  S+  +TG+Y +D  +
Sbjct: 119 DSFYSNNANSALLLHKVENPSQYGVAVVEDTL-IIKLVEKPKEFVSDLIITGVYIFDKSI 177

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
                 +KPS+RGELEIT   Q  LE G      L +G+ W DTG    ++EA+  +
Sbjct: 178 FMAIDNIKPSQRGELEITDAIQKQLETGGRVTYELIQGW-WKDTGQLQDILEANRLM 233


>UniRef50_A8KY05 Nucleotidyl transferase n=6 Tax=Actinomycetales RepID=A8KY05_FRASN
          Length = 843

 Score =  227 bits (579), Expect = 3e-58,   Method: Composition-based stats.
 Identities = 72/296 (24%), Positives = 122/296 (41%), Gaps = 14/296 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +++AGG GTRL P+T  + K LLP+ ++P++ + L +L   G  E  ++T       
Sbjct: 1   MRAVVMAGGEGTRLRPLTANLPKPLLPVVNRPIMEHVLRLLKRHGFDE-TVVTVQFLAAM 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   G G E G+ L YA + +P G A +    E  L  E   LV+  +       +  +
Sbjct: 60  IRNYFGSGDELGMHLSYATETTPLGTAGSVKNAEDALRHEE-FLVISGDALTDIDLTDLV 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
            +  A+    TV    V DP  FG+V   ++ R     EKP   Q  S+   TG+Y  + 
Sbjct: 119 AYHRAQGALVTVALKSVPDPLEFGIVITGEDGRISRFLEKPTWGQVFSDTVNTGIYVMEP 178

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +V+++    +  +        +    + AG      +  G  W D GT  S   A   V 
Sbjct: 179 EVLDHVPAGEAVD----WSGDVFPRLVAAGAPVFGYVA-GGYWEDVGTIASFQRAQADV- 232

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTG-YGQYLLELLRARPRQY 293
            + ++    I   E       W+ ++      + L      G Y      A  R++
Sbjct: 233 -LNRQVDVSIGGFEVSP--GVWIGEDADVHPDAILKGPLVVGDYSKVEAGAELREF 285


>UniRef50_A8FIL3 Spore coat polysaccharide biosynthesis protein SpsI n=7
           Tax=cellular organisms RepID=A8FIL3_BACP2
          Length = 246

 Score =  227 bits (578), Expect = 5e-58,   Method: Composition-based stats.
 Identities = 103/249 (41%), Positives = 158/249 (63%), Gaps = 5/249 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+ILAGG G+RL P+T+  +K LLP+   PMIY+ L  L  AGI ++++I+  E    
Sbjct: 1   MKGVILAGGKGSRLAPLTKIFNKHLLPVGPYPMIYWSLFKLKEAGILDVMVISQAEQIPL 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           FQ+LL    E G+ + Y  QP   G++      + F+ GE   L+LGDN+F     SP +
Sbjct: 61  FQKLLEGDQELGMNIVYQVQPEASGISDGLSYAKPFVEGEKFVLMLGDNVFED-SLSPFV 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDD-NFRAISLEEKPKQPKSNWAVTGLYFYDSK 179
                +  GA V   +V DP+RFG+ E D  + R +S+EEKP+ P+S++ VTG+YFYD +
Sbjct: 120 DAFQRQESGAKVLLKEVTDPKRFGIAEIDAVHQRIVSIEEKPEHPRSSYCVTGIYFYDQE 179

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS-TFVQ 238
           V +Y +++ PS+RGELEIT +N +Y+    LT ++L     W+D GTH+SL +AS    +
Sbjct: 180 VFQYIEKISPSDRGELEITDVNNLYISNSQLTYDMLK--GWWIDAGTHESLHQASTKMFE 237

Query: 239 TVEKRQGFK 247
           T++K++G++
Sbjct: 238 TMKKKEGYE 246


>UniRef50_B8CYH8 Phosphoglucomutase n=1 Tax=Halothermothrix orenii H 168
           RepID=B8CYH8_HALOH
          Length = 820

 Score =  226 bits (577), Expect = 6e-58,   Method: Composition-based stats.
 Identities = 66/278 (23%), Positives = 120/278 (43%), Gaps = 13/278 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+I+AGG G+RL P+T  + K ++P+ + P++ Y +++L   GI++I  +TT      
Sbjct: 1   MKGVIMAGGQGSRLRPLTCNLPKPMVPVMNYPVMEYIITLLKNYGIKDIA-VTTYYLPNK 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDGS++G+ L Y  +  P G A +      FL  +   +V+  +          +
Sbjct: 60  IESYFGDGSKWGVNLHYFVEKEPLGTAGSVANARDFL--DEPFMVISGDAITDFDLGEAI 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
                +   AT+   +V  P  +GVV  D+  R +   EKP   Q  S+   TG+Y  + 
Sbjct: 118 SFHQEKGASATIVLARVKTPLDYGVVITDERGRIVRFLEKPNWGQVFSDTVNTGIYVLEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           ++ +   +    +        +  + LE       +  +G+ W D G+ +  I  +    
Sbjct: 178 EIFDLYDKGINFDF----SKDLFPLMLEKNWNLYGISLKGY-WNDIGSLEEYINTNFDFF 232

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKT 276
             E     +  C+ +    N WL D       + L   
Sbjct: 233 KGEIDLPLEACCVLD---NNIWLQDGVEIDETAELEGP 267


>UniRef50_D2AV47 Phosphoglucomutase/phosphomannomutase family protein n=27
           Tax=Bacteria RepID=D2AV47_STRRD
          Length = 828

 Score =  226 bits (577), Expect = 7e-58,   Method: Composition-based stats.
 Identities = 72/291 (24%), Positives = 118/291 (40%), Gaps = 14/291 (4%)

Query: 6   LAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQRLL 65
           +AGG GTRL P+T    K LLP+ ++P++ + L +L   G+ E  ++T        +   
Sbjct: 1   MAGGEGTRLRPMTANQPKPLLPVINRPIMEHVLRLLRRHGLTE-TVVTVQFLAALVRNYF 59

Query: 66  GDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHVAA 125
           GDG E G+ L YA + +P G A +       L  +   LV+  +       +  +R    
Sbjct: 60  GDGDELGMSLYYATEDTPLGTAGSVKNAADKLRDDR-FLVISGDALTDIDLTDMIRFHRE 118

Query: 126 RTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDSKVVEY 183
                T+   +V +P  FG+V  DD+ R     EKP   Q  S+   TG+Y  + +V++ 
Sbjct: 119 NGALVTIGLKRVPNPLEFGIVIVDDHGRVERFLEKPTWGQVFSDTVNTGIYVMEPEVLDE 178

Query: 184 AKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEKR 243
                P +        +    L  G      +  G+ W D GTH+S + A   V +    
Sbjct: 179 IAAGVPVD----WSADVFPRLLARGAPLYGYVAEGY-WEDVGTHESYLRAQADVLSGR-- 231

Query: 244 QGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY-GQYLLELLRARPRQY 293
              ++           W+ +       + L    Y G Y      A  R+Y
Sbjct: 232 --VRVDTDAFEVSPGVWVAEGASVDTDAVLKGPLYIGDYAKVEAGAELREY 280


>UniRef50_Q2RH64 Nucleotidyl transferase n=1 Tax=Moorella thermoacetica ATCC 39073
           RepID=Q2RH64_MOOTA
          Length = 821

 Score =  226 bits (576), Expect = 7e-58,   Method: Composition-based stats.
 Identities = 60/241 (24%), Positives = 105/241 (43%), Gaps = 10/241 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK II+AGG G+RL P+T    K L+P+ ++P++ Y + +L   GI+E+  +T       
Sbjct: 1   MKAIIMAGGEGSRLRPLTCKRPKPLVPVANRPVMEYCVDLLRELGIKEVG-VTLQYLPQL 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDGS+FG+ L Y  +  P G A +       L  + + +V+  +        P +
Sbjct: 60  IEEYFGDGSDFGLHLHYFVEDKPLGTAGSVKNAAAIL--DETFVVVSGDALTDFDLRPAI 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
                    AT+    V +P  +GVV  + +    S  EKP   +  S+   TG+Y  + 
Sbjct: 118 ARHKESGALATLVLTAVDNPLEYGVVITNPDGSIRSFLEKPSWGEVFSDRVNTGIYILEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +V+E   + +P +        +    L+       +   G+ W D G      +A   + 
Sbjct: 178 EVLELIPEGRPFDF----SKDLFPRLLKEKRPLYGVTLSGY-WCDIGNLTQYRQAQEDIL 232

Query: 239 T 239
            
Sbjct: 233 R 233


>UniRef50_A9B3S0 Nucleotidyl transferase n=6 Tax=Chloroflexi (class)
           RepID=A9B3S0_HERA2
          Length = 835

 Score =  226 bits (576), Expect = 8e-58,   Method: Composition-based stats.
 Identities = 60/242 (24%), Positives = 105/242 (43%), Gaps = 9/242 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +++AGG G+RL P+T    K ++P+ D+P++ + + +L   GI +I+I         
Sbjct: 1   MKAVLMAGGEGSRLRPLTISRPKPMVPLVDRPVMGHIIELLKRHGITDIIITVQY-LANI 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGE-PSCLVLGDNIFFGQGFSPK 119
            Q   GDGS F + + Y+ +  P G A A       ++ +    LV+  +       +  
Sbjct: 60  IQDFYGDGSAFDVDISYSVEEVPLGTAGAVKYASRLIDDDSEPILVISGDALTDFDLTAL 119

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYD 177
           +         AT+   +V +P  +GVV  DD  R     EKP   +  S+   TG+Y  D
Sbjct: 120 IEAHKRSNAKATITLTRVPNPLEYGVVITDDTGRIRQFLEKPSWGEVFSDTVNTGIYVID 179

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
             V++     +P +        +    L  G L    +  G+ W D G  ++ + A +  
Sbjct: 180 PCVLDDIPLGEPFDF----SKDLFPALLRRGELLHGYIAEGY-WTDVGNIEAYMRACSDY 234

Query: 238 QT 239
             
Sbjct: 235 LM 236


>UniRef50_Q1J1J1 Glucose-1-phosphate thymidyltransferase n=10 Tax=Deinococci
           RepID=Q1J1J1_DEIGD
          Length = 355

 Score =  225 bits (575), Expect = 9e-58,   Method: Composition-based stats.
 Identities = 80/235 (34%), Positives = 115/235 (48%), Gaps = 5/235 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK II A G GTRL P+T    K +LP+   P+I + L  L+ AGI E+ II +   +  
Sbjct: 4   MKAIIPAAGLGTRLRPLTYTRPKPVLPVAGAPIIVHALRTLLAAGINEVGIIVSDATRAE 63

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
             + L    E  +Q+    Q    GL  A +    ++  +  C+ LGDN+F   G +P +
Sbjct: 64  IAQTLEQVPE--VQVTLINQHEQLGLGHAVLTARNWVGQQNFCVYLGDNLF-EHGVAPFI 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                    A +   +V DP  FGV E +   R   L EKPK P SN AV GLY +  +V
Sbjct: 121 ERFQREQAAAVIALVEVPDPTAFGVAELEGE-RITRLVEKPKVPPSNLAVAGLYCFTPEV 179

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAST 235
            +    + PS RGE EIT   Q  ++ G   +    +G+ W DTG    L++A+ 
Sbjct: 180 FDVLDGMPPSARGEYEITDAIQGLVDRGQTVLGQCVQGW-WKDTGRPADLLDANR 233


>UniRef50_C0GEN7 Nucleotidyl transferase n=1 Tax=Dethiobacter alkaliphilus AHT 1
           RepID=C0GEN7_9FIRM
          Length = 824

 Score =  225 bits (575), Expect = 1e-57,   Method: Composition-based stats.
 Identities = 62/236 (26%), Positives = 106/236 (44%), Gaps = 10/236 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK II+AGG G+RL P+T    K ++PI ++PM+ + +S+L    ++EI  +T       
Sbjct: 1   MKAIIMAGGQGSRLRPLTCDRPKPMVPIMNRPMMEHIVSLLKSYDLKEIG-VTLQYLPEQ 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDG EFG+ + Y  + SP G A +     +FL  + + +V+  +          +
Sbjct: 60  IENYFGDGREFGVNMRYFIEDSPLGTAGSVKNSGSFL--DETFIVISGDALTDFDLQKAI 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
               A+   AT+    V  P  +GVV  +D  R     EKP   +  S+   TG+Y  + 
Sbjct: 118 EFHRAKGGVATLVLTSVETPLEYGVVIANDEGRITQFLEKPSWGEVFSDTVNTGIYILEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
           +V++Y     P          +  + ++ G      +  G+ W D G  +    A 
Sbjct: 178 EVLQYV----PEGAQFDFAKDLFPLLMQKGYPLYGYVAEGY-WCDIGNIEQYHGAH 228


>UniRef50_A3DK29 Nucleotidyl transferase n=13 Tax=Clostridia RepID=A3DK29_CLOTH
          Length = 349

 Score =  225 bits (574), Expect = 1e-57,   Method: Composition-based stats.
 Identities = 65/239 (27%), Positives = 113/239 (47%), Gaps = 10/239 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +K + LAGG GTRL PIT  + K ++PI  KP++   +  L   GI E+++ T  +    
Sbjct: 3   VKALFLAGGLGTRLRPITNDLPKPMVPIMGKPLLERNIEKLKSYGIDEVVLSTCYKPHK- 61

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
             +  GDG +FG+++ Y  +  P G A A    E  L+   + LV   +I      +  +
Sbjct: 62  IDKYFGDGKKFGVKISYITEDKPLGTAGAIKNAEELLSD--TFLVFNADILSDIDIANMI 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
           R    +   AT+   +V +P  +GV+E DD+    + +EKP+  + KSN    G+Y ++ 
Sbjct: 120 RFHKEKGALATIAVTKVDNPSAYGVIEHDDDNFITAFKEKPQPHESKSNLINAGVYIFEK 179

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
           +++ +     P  R          + LE G   + +  +   WLD GT    ++    +
Sbjct: 180 ELLNHI----PRGRAVSIERETYPLLLEKGYK-MAVYNKCGYWLDLGTPGKYLKVHKDI 233


>UniRef50_UPI0001C3666A glucose-1-phosphate thymidylyltransferase n=1 Tax=Clostridium
           hathewayi DSM 13479 RepID=UPI0001C3666A
          Length = 291

 Score =  224 bits (572), Expect = 3e-57,   Method: Composition-based stats.
 Identities = 133/188 (70%), Positives = 154/188 (81%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKGIILAGGSGTRL+P+T   SKQLLPIYDKPMIYYPLSVLM AGIR+ILII+TP+D   
Sbjct: 1   MKGIILAGGSGTRLYPLTMVTSKQLLPIYDKPMIYYPLSVLMNAGIRDILIISTPDDTPR 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F+ LLG GS+FGI+L YA QPSPDGLAQAFIIGE F+  +   ++LGDNIF G G + +L
Sbjct: 61  FEALLGSGSQFGIRLSYAVQPSPDGLAQAFIIGEEFIGDDNVAMILGDNIFAGHGLTKRL 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
              A + EGATVFGY V DPERFG+VEFD N +AIS+EEKP+ PKSN+ VTGLYFYD+KV
Sbjct: 121 LAAANKKEGATVFGYYVDDPERFGIVEFDSNGKAISIEEKPEHPKSNYCVTGLYFYDNKV 180

Query: 181 VEYAKQVK 188
           VEYAK  K
Sbjct: 181 VEYAKNFK 188


>UniRef50_A7GSW4 Nucleotidyl transferase n=73 Tax=cellular organisms
           RepID=A7GSW4_BACCN
          Length = 785

 Score =  223 bits (568), Expect = 6e-57,   Method: Composition-based stats.
 Identities = 73/280 (26%), Positives = 117/280 (41%), Gaps = 15/280 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+ILAGG G RL P+T  V K +LP+ +KP++ Y + +L   GIREI I         
Sbjct: 3   MKGVILAGGKGRRLRPLTCNVPKPMLPLLEKPVLEYNIELLRRHGIREIAITVQY-LSNT 61

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDGS++G++L Y E   P G A +    E FL  +   +V+  +       +  +
Sbjct: 62  IREYFGDGSKWGVKLHYFEDSPPLGTAGSIKQAEAFL--DEPFVVISGDALTDFPLTEGI 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
                +    T+F  +V +P  FG+V  +     I   EKP   +  SN   TG+Y  D 
Sbjct: 120 VFHQQKKRMLTMFVKEVENPLSFGLVVMNKEQEIIRYMEKPSWNEVISNVVNTGIYIMDP 179

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
            +  Y      ++             LE  N        G+ W+D GT +   +A     
Sbjct: 180 SIFSYIPPKTYADFSRHIFP-----LLENTNALFGYKAEGY-WMDIGTFEQYRQA--QFD 231

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
            + K+    I   E +     W+ +       + +    +
Sbjct: 232 LLTKKVNVTIPYTEVLP--MVWMGEAVTIEKGTKIHGPSF 269


>UniRef50_Q3Z778 Nucleotidyltransferase family protein n=5 Tax=Dehalococcoides
           RepID=Q3Z778_DEHE1
          Length = 361

 Score =  222 bits (565), Expect = 1e-56,   Method: Composition-based stats.
 Identities = 59/238 (24%), Positives = 100/238 (42%), Gaps = 10/238 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK IIL GG GTRL P++    K ++P+ + P + + L  L   GI++I I+T       
Sbjct: 1   MKAIILVGGQGTRLRPLSINTPKSMVPVLNVPFLSHVLRYLSSCGIKDI-ILTQGHLAAP 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            ++  G+G   G+ L Y+ +    G A A    E +L  + + + L  +IF     S  L
Sbjct: 60  IEQYFGNGQSLGVNLVYSVEHEALGTAGAIKNAERYL--DDTFITLNGDIFTHLDLSAML 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQP--KSNWAVTGLYFYDS 178
           R    +    ++    V DP ++G+VE  D  R     EKP      +N    G Y  + 
Sbjct: 118 RAHRDKKALVSIALTPVDDPTKYGLVETADGGRVSRFLEKPSPAQITTNMINAGTYIIEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTF 236
           +V++Y     P+         +    L             + W+D G+ +   + +  
Sbjct: 178 EVLKYI----PAGENHSFERQLFPRLLNECQAVYAYPSSAY-WIDIGSPEKYSQLNRD 230


>UniRef50_B9MMF1 Nucleotidyl transferase n=1 Tax=Anaerocellum thermophilum DSM 6725
           RepID=B9MMF1_ANATD
          Length = 712

 Score =  222 bits (565), Expect = 1e-56,   Method: Composition-based stats.
 Identities = 62/278 (22%), Positives = 121/278 (43%), Gaps = 18/278 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+I+AGGSGTRL P+T  + K ++P + KP++ Y + +L   GI EI           
Sbjct: 1   MKGVIMAGGSGTRLRPLTVSLPKPMIPFFGKPVMEYAVKLLKAHGIFEIATTLQYHPDKI 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                 DG ++G+ +++  +  P G A +    + FL  + + +VL  +       +  +
Sbjct: 61  I-NYFEDGQKWGVNIQHFVEDRPLGTAGSVKNAKVFL--DDTFVVLSGDGITNADLTRAI 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDS 178
                +    T+   +V  P  +G+V  D+  +     EKP   +  SN A TG+Y  + 
Sbjct: 118 EFHKQKGSKVTIVLKEVEIPIEYGIVLTDEEGKIQRFFEKPSWSEVFSNLANTGIYIIEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           ++++Y +  KP +        +    L+           G+ W D G   S I+A   + 
Sbjct: 178 EILDYIEDGKPFDF----SKDLFPKLLKEKVPMFGFKMDGY-WCDIGDVGSYIKAHRDI- 231

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKT 276
                  FK+  + ++  ++  +         + ++++
Sbjct: 232 -------FKLGGILDLDLKSSQISKNSNISLNAKISRS 262


>UniRef50_A7NP37 Nucleotidyl transferase n=5 Tax=Chloroflexaceae RepID=A7NP37_ROSCS
          Length = 370

 Score =  221 bits (564), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 70/276 (25%), Positives = 114/276 (41%), Gaps = 13/276 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +IL GG GTRL P+T    K ++P+ ++P I + L  L   GI E+++         
Sbjct: 1   MKAVILVGGLGTRLRPLTCNTPKPMIPLVNQPFIVHVLENLRNQGIDEVILCVQY-LADR 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F+  LGDGS  G+++   E+P P G A A    E  L+G     V   ++         L
Sbjct: 60  FREALGDGSVLGLKIHVIEEPEPLGTAGAVKNVEHMLDGSTF--VFNGDVLTDLDLRAML 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
                R    T+    V DP  +G+VE D+        EKP+  +  SN    G Y  + 
Sbjct: 118 AFHRERGSKLTIALTPVEDPTAYGLVEMDETGHIRRFMEKPRVDEITSNLINAGTYIIEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           ++  Y     P ++  +    +  + L+  +         + W D GT  + +E    + 
Sbjct: 178 ELFRYV----PPKQHYMFERGLFPVVLQTRDPMYGYPSPAY-WTDIGTPSAYLEVHHDIL 232

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLA 274
             + R  F     +EI  R   + D  +   A  + 
Sbjct: 233 VGKVRYRF---HGKEIGNRVWLVGDADIHPRAQVIG 265


>UniRef50_D2PJ00 Glucose-1-phosphate thymidyltransferase n=15 Tax=Archaea
           RepID=D2PJ00_SULIS
          Length = 346

 Score =  221 bits (564), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 84/278 (30%), Positives = 134/278 (48%), Gaps = 7/278 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +IL GG GTRL P+T    KQL+ I  KP+  + L  +  AGI++I+II    +   
Sbjct: 1   MQAVILHGGQGTRLRPLTHTGPKQLIKIAGKPVSQWVLEQIRDAGIKDIIIILGDNNPNK 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                G+GS FG+ + Y  Q    GLA A    +  +  +   + LGDNI         L
Sbjct: 61  VVEYYGEGSRFGVNVTYVYQGKARGLADAVYKVKDVITEDRFLVYLGDNIVPYDNLPSFL 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                    A++   +V +P RFGV     + + I L EKPK+  S+ A+ G+Y +  ++
Sbjct: 121 SF----KGSASILLAKVDNPNRFGVAII-KDGKVIRLVEKPKEKISDSALVGVYAFTREI 175

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            E  + +KPS RGELEIT   Q  ++ G      +  G+ W DTGT   ++EA++F+   
Sbjct: 176 FEVIENLKPSWRGELEITDAIQGLIDRGREVEYKIIDGW-WKDTGTPKDILEANSFLLDK 234

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
              +  +    E       +++ E +    S++    Y
Sbjct: 235 YAERKIEGEVRESSIDGRVFIEKEALIEN-STIRGPAY 271


>UniRef50_B8I5R7 Nucleotidyl transferase n=1 Tax=Clostridium cellulolyticum H10
           RepID=B8I5R7_CLOCE
          Length = 810

 Score =  221 bits (564), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 64/263 (24%), Positives = 113/263 (42%), Gaps = 15/263 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK II+AGG G+RL P+T  + K ++PI +KP++ + + +L   GI +I I T       
Sbjct: 1   MKAIIMAGGEGSRLRPLTCDLPKPMVPIMNKPVLEHTIGLLKSYGITDIGI-TLLYHPQI 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   G G   G+ + Y  + SP G A        FL  + + +V+  +          L
Sbjct: 60  IKDYFGSGHSCGVNIYYFLEESPLGTAGGIKNAREFL--DETFIVISGDSLTDLNIENAL 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
            +  ++   AT+   +V  P  +GVV  D++       EKP   +  S+   TG+Y  + 
Sbjct: 118 EYHRSKKSIATLILTKVDVPLEYGVVLTDEDGSIKGFVEKPSWGEIFSDMVNTGIYILEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +++ Y +  K ++        +    L +       +   + W D G   S I  ++   
Sbjct: 178 EILSYIEVGKNTDF----SRDVFPALLSSSKKIFGYVSNDY-WCDIGDTRSYI--NSHYD 230

Query: 239 TVEKRQGFKIACLEEIAWRNGWL 261
            + K     I   EE+   N W+
Sbjct: 231 ILNKNLKIDIG--EELDE-NIWV 250


>UniRef50_C3LKU6 Nucleotidyl transferase family protein n=8 Tax=Bacillus
           RepID=C3LKU6_BACAC
          Length = 679

 Score =  221 bits (563), Expect = 3e-56,   Method: Composition-based stats.
 Identities = 70/236 (29%), Positives = 106/236 (44%), Gaps = 11/236 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+ILAGG G RL P+T    K +LP+ +KP++ Y + +L   GIREI I         
Sbjct: 1   MKGVILAGGKGRRLRPLTCNTPKPMLPLLEKPVLEYNIELLRQHGIREIAITVQYMSTA- 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            ++  GDGS++G+ L Y E   P G A +    E FL  + + +V+  +       S  +
Sbjct: 60  IKQYFGDGSKWGVNLYYFEDSPPLGTAGSIKQAEKFL--DETFVVISGDALTDFQLSKGI 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
                +    T+F  +V +P  FG+V  +         EKP   +  SN   TG+Y  + 
Sbjct: 118 TFHEQQKRMVTMFVKEVENPLSFGLVVMNKEQEVTRYIEKPSWNEVVSNIVNTGIYIMEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
           ++  Y        R   + +      L   N     L  G+ WLD GT D   +A 
Sbjct: 178 EIFSYIP-----PREFFDFSQDVFPLLANKNALFAYLSEGY-WLDIGTFDQYRQAQ 227


>UniRef50_B9KYJ6 Glucose-1-phosphate thymidylyltransferase n=5 Tax=cellular
           organisms RepID=B9KYJ6_THERP
          Length = 258

 Score =  221 bits (563), Expect = 3e-56,   Method: Composition-based stats.
 Identities = 115/279 (41%), Positives = 161/279 (57%), Gaps = 26/279 (9%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG++LAGG GTRL+P+T   +K LLP+YD+PMIYYP+  L+ AGI EI+++T     G 
Sbjct: 1   MKGVVLAGGLGTRLYPLTFATNKHLLPVYDQPMIYYPIQTLVKAGIDEIMVVTGGPHAGD 60

Query: 61  FQRLLGDGSEFGIQ-LEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK 119
           F R+L +G   G++ LEYA Q    G+A A  + E F +GE  C++LGDN        P 
Sbjct: 61  FLRVLRNGRHLGVRHLEYAYQEEERGIADALSLCEEFADGEHICVILGDN-TTDADIRPA 119

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNF--RAISLEEKPKQPKSNWAVTGLYFYD 177
           +      T GA +F  +V DP RFG   FD N   R + +EEKPK+PKS +AVTGLY YD
Sbjct: 120 VESF---TGGALIFLARVPDPHRFGCPVFDPNDPTRILRIEEKPKEPKSPYAVTGLYLYD 176

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
           ++V E+ ++++PS RGELEIT +N  YLE G L    +     W D GT +SL  A+ + 
Sbjct: 177 NRVFEFIRELEPSPRGELEITDVNNRYLELGLLRW--VELQGFWSDAGTFESLHRANRYW 234

Query: 238 QTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKT 276
                            A R G+ D + +  +A    ++
Sbjct: 235 -----------------AERRGYRDPDPILPSALPAGRS 256


>UniRef50_C7ICW0 Nucleotidyl transferase n=1 Tax=Clostridium papyrosolvens DSM 2782
           RepID=C7ICW0_9CLOT
          Length = 815

 Score =  220 bits (562), Expect = 3e-56,   Method: Composition-based stats.
 Identities = 58/256 (22%), Positives = 108/256 (42%), Gaps = 10/256 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +I+AGG G+RL P+T  + K ++P+ +KP++ + + +L   GI +I I T       
Sbjct: 6   MKAVIMAGGEGSRLRPLTCDLPKPMVPVMNKPVLEHTIGLLKSYGITDIGI-TLLYHPQI 64

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   G G   G+ + Y  + SP G A        FL  + + +V+  +          L
Sbjct: 65  IKDYFGSGHSHGVNIYYFLEESPLGTAGGIKNARDFL--DETFIVISGDSLTDLDIDKAL 122

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
           ++  ++   AT+   +V  P  +GVV  D+N       EKP   +  S+   TG+Y  + 
Sbjct: 123 KYHQSKKSIATLILAKVDVPLEYGVVLTDENGSVKGFVEKPSWGEIFSDMVNTGIYILEP 182

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +++ Y +  K  +        +    L +       +   + W D G   S I +   + 
Sbjct: 183 EILSYIESGKKMDF----SKDVFPALLSSSKQIFGYVTNNY-WCDIGDTHSYINSHCDIL 237

Query: 239 TVEKRQGFKIACLEEI 254
             + +        E +
Sbjct: 238 NGKLKINIGEQFNENV 253


>UniRef50_P08075 Glucose-1-phosphate thymidylyltransferase n=49 Tax=Bacteria
           RepID=STRD_STRGR
          Length = 355

 Score =  220 bits (562), Expect = 3e-56,   Method: Composition-based stats.
 Identities = 90/272 (33%), Positives = 137/272 (50%), Gaps = 8/272 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++LAGG+GTRL PIT   +KQL+P+ +KP+++Y L  +  AGI ++ I+   +    
Sbjct: 1   MKALVLAGGTGTRLRPITHTSAKQLVPVANKPVLFYGLEAIRAAGIIDVGIVVG-DTADE 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
               +GDGS FG+++ Y  Q  P GLA   +I   FL  +   + LGDN   G      +
Sbjct: 60  IVAAVGDGSRFGLKVSYIPQSKPLGLAHCVLISRDFLGEDDFIMYLGDNFVVGV-VEDSV 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           R   A    A +   +V +P  FGV E  D+ + + LEEKP  PKS+ A+ G+Y +   +
Sbjct: 119 REFRAARPDAHLMLTRVPEPRSFGVAELSDSGQVLGLEEKPAHPKSDLALVGVYLFSPAI 178

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            E    + PS RGELEIT   Q  ++AG      +  G+ W DTG    ++E +  V   
Sbjct: 179 HEAVAAITPSWRGELEITDAVQWLIDAGRDVRSTVISGY-WKDTGNVTDMLEVNRLVLET 237

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASS 272
                 +  C   +  R+  +    V+  A  
Sbjct: 238 -----TEPRCDGLVDERSDLIGRVLVEEGAEV 264


>UniRef50_A3DL04 Nucleotidyl transferase n=1 Tax=Staphylothermus marinus F1
           RepID=A3DL04_STAMF
          Length = 837

 Score =  220 bits (560), Expect = 6e-56,   Method: Composition-based stats.
 Identities = 56/241 (23%), Positives = 103/241 (42%), Gaps = 7/241 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +K II+AGG GTRL P+T    K L+P+ +KP++ + + +L   G ++I  +T       
Sbjct: 2   VKAIIMAGGEGTRLRPLTVNRPKPLVPLVNKPLMEHVVHLLKSKGFKDIG-VTLHYLPNT 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
             R  GDGSEFG+++ Y+ +  P G A          + + + +V+  ++F        L
Sbjct: 61  IMRYFGDGSEFGVRIYYSIEEKPLGTAGGVRFLADKYDWDETIIVISGDVFTNIDLEKML 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDS 178
            +   +    T+   +  DP ++G+   D+  R     EKP   +  S+    G+Y  + 
Sbjct: 121 EYHRRKGSIFTMAVRKTDDPTKYGIALLDEEGRVRRFLEKPSWSEVFSDLINMGIYILEP 180

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           + +E      PS        ++    L             + W D G+ +   E    + 
Sbjct: 181 EALEMI----PSNEEYDFAKNLIPKLLRFDKPVYGWRADNYYWSDIGSINQYKETHNDIL 236

Query: 239 T 239
           +
Sbjct: 237 S 237


>UniRef50_A0Q1V6 Mannose-1-phosphate guanyltransferase (Pyrophosphorylase domain and
           phosphomannomutase domain) n=4 Tax=Firmicutes
           RepID=A0Q1V6_CLONN
          Length = 817

 Score =  220 bits (560), Expect = 6e-56,   Method: Composition-based stats.
 Identities = 68/297 (22%), Positives = 120/297 (40%), Gaps = 25/297 (8%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +I+AGG G RL P+T  + K ++PI +KP I Y + +L  +GI++I I T       
Sbjct: 1   MKAVIMAGGLGNRLRPLTCNIPKPMMPIVNKPAIQYIIELLKNSGIKDIAI-TLQYLADE 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                 DGS FG+ ++Y  +  P G   +    E FL  + + +V+  +          +
Sbjct: 60  IMSYFQDGSRFGVNIKYFIEDMPLGTGGSVKNAEEFL--DDTFIVISGDALINLDLRKVV 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDS 178
           ++  ++    T+   +V  P  +GVV  D+  R I   EKP   +  S+   TG+Y  + 
Sbjct: 118 KYHKSKNAQVTIVTKKVNTPLEYGVVITDNEGRIIKFLEKPGWSEVFSDKVNTGVYVLEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
            V++Y  + K  +        +  + L             + W D G  +   + +  + 
Sbjct: 178 DVLKYYDKNKQFDF----SKDLFPLLLIKNKRIFSYTISEY-WCDIGDFNEYHKCNLDLL 232

Query: 239 T---------VEKRQGFKIACLEEIAWRNGWL------DDEGVKRAASSLAKTGYGQ 280
                      E+ Q   I    EI+ +   +      D+  +   A     T  G 
Sbjct: 233 NGIIKVKLDGKEREQNIWIGRNCEISPKAKIIPPVFIGDNTSIHSYAEVGPNTILGS 289


>UniRef50_C1DV53 Mannose-1-phosphate guanyltransferase n=4 Tax=cellular organisms
           RepID=C1DV53_SULAA
          Length = 830

 Score =  219 bits (559), Expect = 7e-56,   Method: Composition-based stats.
 Identities = 65/263 (24%), Positives = 113/263 (42%), Gaps = 13/263 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +I+AGG GTR+ P+T  + K +LP+ +KPM+ + +  +   GI EI+I+        
Sbjct: 1   MKAVIMAGGFGTRIQPLTNSIPKPMLPVLNKPMMEHIIKKVKAVGITEIVILL-YFKPEV 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            Q    DGS+FGI++ Y       G A A      +L  +   +V+  ++         +
Sbjct: 60  IQNYFKDGSDFGIKINYVLPDDDYGTAGAVKKAAKYL--DERFIVISGDLVTDFDLKEII 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDS 178
               A     T+    V DP +FGVV  D + + +   EKP   +  S+   TG+Y  + 
Sbjct: 118 GFHQAVGSKLTITLTSVEDPLQFGVVITDKDGKILRFLEKPGWGEVFSDTINTGIYVIEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +++ Y     P +        +    ++ G        +G+ W D G  +S  E +  + 
Sbjct: 178 EILNYIPDNLPFDF----SKDLFPKLMKEGITLYGYNAKGY-WRDVGNPESYREVNKDIL 232

Query: 239 TVEKRQGFKIACLEEIAWRNGWL 261
             + +   +    E I    G L
Sbjct: 233 LDKVKLDVEG---ERIKVNGGVL 252


>UniRef50_B7GHA3 Nucleoside-diphosphate-sugar pyrophosphorylase fused to
           phosphomannomutase n=1 Tax=Anoxybacillus flavithermus
           WK1 RepID=B7GHA3_ANOFW
          Length = 815

 Score =  219 bits (558), Expect = 9e-56,   Method: Composition-based stats.
 Identities = 63/257 (24%), Positives = 109/257 (42%), Gaps = 14/257 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +K +I+AGG GTRL P+T  V K ++PI +KP++ Y +  L   GI +I +         
Sbjct: 23  VKAVIMAGGRGTRLRPLTCHVPKPIVPIMNKPVMAYSIEWLKHHGITDIAVTVQYLSDEI 82

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDG  FG++L Y E+ +P G A +    ++FL  + + +V+  +I         +
Sbjct: 83  IE-YFGDGRRFGVRLHYFEETTPLGTAGSVKHAQSFL--DDTFVVISADILTTMHLQQAI 139

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
               ++    TV  +    P  +G +  D N + I   EKPK  +  S+   TG+Y  D 
Sbjct: 140 HFHFSKQALVTVLMHHEATPLSYGGIVTDRNGKVIHFVEKPKWNEVCSDLVNTGIYICDP 199

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
            +  Y  +  P +  +     + Q         +        W D G  +   +    + 
Sbjct: 200 AIFNYMPEHPPYDFSQHIFPHLIQ-----QKYPIYGYEADGYWSDIGVIEQYHQTHVDLL 254

Query: 239 TVEKRQGFKIACLEEIA 255
                Q    +  +EIA
Sbjct: 255 ----NQRLIPSHYKEIA 267


>UniRef50_Q97EX5 Mannose-1-phosphate guanyltransferase (Pyrophosphorylase domain and
           phosphomannomutase domain) n=1 Tax=Clostridium
           acetobutylicum RepID=Q97EX5_CLOAB
          Length = 815

 Score =  219 bits (558), Expect = 9e-56,   Method: Composition-based stats.
 Identities = 63/236 (26%), Positives = 107/236 (45%), Gaps = 10/236 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK II+AGG G RL P+T  + K ++PI  KP++ Y + +L   GI EI I T       
Sbjct: 1   MKAIIMAGGQGKRLRPLTCNLPKPMMPIMQKPVLQYIIELLKKHGINEIGI-TLHYLPDE 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                GDG E G+ + Y  + SP G A +    E+FL  + + +V+  +       +  L
Sbjct: 60  VMDYFGDGKELGVNIHYFIEQSPLGTAGSVRNAESFL--DETFVVISGDALTDVNLTNIL 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDS 178
           ++   +    T+   +V  P  +GV   D   R  +  EKP   +  S+ A TG+Y  + 
Sbjct: 118 QYHKEKNAMVTIVLKKVTIPLEYGVAITDTEGRISNFIEKPGWGEIFSDKANTGIYVMEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
            + E+  + K  +  E     +    L++G      +   + W D G  +  ++ +
Sbjct: 178 GIFEFYNKDKKFDFSE----ELFPELLKSGKEIFGYVVNDY-WRDIGNIEQFMKCN 228


>UniRef50_Q8CUH8 Spore coat polysaccharide synthesis (Glucose-1-phosphate
           thymidyltransferase) n=1 Tax=Oceanobacillus iheyensis
           RepID=Q8CUH8_OCEIH
          Length = 239

 Score =  219 bits (558), Expect = 1e-55,   Method: Composition-based stats.
 Identities = 99/242 (40%), Positives = 149/242 (61%), Gaps = 4/242 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+ILA G GTRLHP+T+ ++K L+PI   PMIYYP+  L    I EILI T  +D   
Sbjct: 1   MKGMILARGKGTRLHPLTKVINKHLIPIGKYPMIYYPIFKLREVDITEILITTNQQDIPL 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F+ LLGDG + G+++ +  Q    G+  A ++ +TF+  +   ++LGDNIF      P +
Sbjct: 61  FRELLGDGRDLGVRIHFEAQQQAIGIPDAILLSKTFVGSDKLTVILGDNIFHD-SLIPYV 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFR-AISLEEKPKQPKSNWAVTGLYFYDSK 179
           +    ++ GA +    V DP R+G+  FD + +  +S+EEKP    SN+ VTG+Y Y ++
Sbjct: 120 QSYEKQSTGAKILLKTVSDPNRYGIATFDKSQKNILSIEEKPSDSSSNYCVTGIYMYGTE 179

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           V E+ KQ+ PS RGELEIT +N +YL+   LT ++L     W+D GT+DS+ +A+  +  
Sbjct: 180 VFEFIKQITPSSRGELEITDVNNLYLQKSKLTFDVLPNW--WIDAGTYDSIFQANQIILK 237

Query: 240 VE 241
            E
Sbjct: 238 NE 239


>UniRef50_Q1AW30 Nucleotidyl transferase n=1 Tax=Rubrobacter xylanophilus DSM 9941
           RepID=Q1AW30_RUBXD
          Length = 833

 Score =  219 bits (557), Expect = 1e-55,   Method: Composition-based stats.
 Identities = 62/242 (25%), Positives = 104/242 (42%), Gaps = 7/242 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +I+AGG GTRL P+T    K ++ I + P + + +++L   G  +I  +T       
Sbjct: 1   MKAVIMAGGQGTRLRPLTSEQPKPMIRIANVPCMEHIVNLLKRHGFTDIA-VTLQFMPDE 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGE-PSCLVLGDNIFFGQGFSPK 119
            +   GDGS++G+ + Y+ + SP G A +  + E  L  E    L++  +          
Sbjct: 60  IRDYFGDGSDWGVNIRYSVEDSPAGTAGSVKMAERQLGLEGERLLIISGDALTDVDLGEL 119

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYD 177
           L +   +   AT+    V +P  FG+V   ++ R     EKP   Q  S+   TG+Y  +
Sbjct: 120 LAYHEQKGGEATMVLKSVENPLDFGIVITGEDGRISRFLEKPAWGQVFSDTVNTGIYLLE 179

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
             V+       P E        +    LE G     ++   + W D GT +    A+  V
Sbjct: 180 PSVLREIP--DPEEGEYDFSKDLFPRLLEQGRPLYGMVTDAY-WEDIGTLEQYASANRDV 236

Query: 238 QT 239
             
Sbjct: 237 LE 238


>UniRef50_A4YHT6 Glucose-1-phosphate thymidyltransferase n=1 Tax=Metallosphaera
           sedula DSM 5348 RepID=A4YHT6_METS5
          Length = 349

 Score =  219 bits (557), Expect = 1e-55,   Method: Composition-based stats.
 Identities = 92/235 (39%), Positives = 132/235 (56%), Gaps = 8/235 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+ILAGG GTRL P+T   +K  +PI +KPM+ Y +  L+ AGIR+I++I  P  +G 
Sbjct: 1   MKGLILAGGHGTRLRPLTHTGNKHAIPIANKPMVLYAVENLVNAGIRDIVVILGPLKEGI 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            + + G+   +     Y EQ  P GLA A +  E +L  EP  + LGDN+    G S  +
Sbjct: 61  KEAIDGN---YPANFTYVEQ-EPLGLAHAVMKAEKYL-DEPFVMHLGDNLL-QNGISQFV 114

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                    A +    V DP ++GVV   +N R   L EKP+ P SN A+ G+Y +   V
Sbjct: 115 NKFHETKADAVIGVTPVKDPRQYGVVVI-ENGRVKRLMEKPRDPPSNLALVGVYVFTPVV 173

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAST 235
            +Y K++KPS RGE EIT + Q+ +E G   VE++     W DTG  + L+EA+ 
Sbjct: 174 HDYTKRLKPSWRGEYEITDVLQLMVEDGRR-VEVVQVEGWWKDTGKPEDLLEANQ 227


>UniRef50_C6D3B0 Nucleotidyl transferase n=1 Tax=Paenibacillus sp. JDR-2
           RepID=C6D3B0_PAESJ
          Length = 330

 Score =  219 bits (557), Expect = 1e-55,   Method: Composition-based stats.
 Identities = 84/245 (34%), Positives = 124/245 (50%), Gaps = 3/245 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+IL  G G+RL+P T+   K L+P+ + P++   +  LM  GI  I I+  P  +  
Sbjct: 1   MKGLILCAGKGSRLYPFTKNRPKTLIPVTNTPLLQLSIMKLMELGIDRIGIVIHPSQEAD 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   G+G  FGI + Y  Q +P G+A A    E +L+GEP  L+LGDN+      S   
Sbjct: 61  IRAQFGEGEAFGISITYIYQHAPKGIANALKNAEYYLSGEPFLLLLGDNLISA-PLSDLK 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
             V      A++   +V DP+ +G+ E  D+ R I LEEKP  PKSN AV G Y +  ++
Sbjct: 120 YDVEHGGVQASLLLAEVADPQDYGIAEIQDS-RIIGLEEKPVHPKSNLAVIGGYAFTKEI 178

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
                ++ PS+RGE EIT   Q  +E        +      +D GT D  + A+  +   
Sbjct: 179 FGAVNKITPSKRGEYEITDAIQWLIEQRYDVAYRVTDQLN-IDVGTKDRWLLANRKLLEA 237

Query: 241 EKRQG 245
           E  Q 
Sbjct: 238 EALQK 242


>UniRef50_C1SHR4 Nucleotidyltransferase n=1 Tax=Denitrovibrio acetiphilus DSM 12809
           RepID=C1SHR4_9BACT
          Length = 830

 Score =  218 bits (556), Expect = 2e-55,   Method: Composition-based stats.
 Identities = 65/235 (27%), Positives = 108/235 (45%), Gaps = 10/235 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +++AGG GTR+ P+T  + K ++P+ +KPM+ Y +  L  AGI EI+I+        
Sbjct: 1   MKAVVMAGGFGTRIQPLTSSMPKPMIPVMNKPMMEYIIDALKEAGIVEIVILL-YFKPEV 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDGS  GI++ Y       G A A    + +L  +   +++  ++     F   L
Sbjct: 60  IKNYFGDGSSKGIKIHYVLPDDDYGTAGAVKKAQKYL--DERFIIVSGDLISDFSFQEIL 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDS 178
                +   AT+    V DP +FGVV  D   + I   EKP   +  S+   TG+Y ++ 
Sbjct: 118 GFHDVKNSKATITLTSVPDPLQFGVVITDKESKIIRFLEKPGWGEVFSDTINTGIYVFEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEA 233
           +++EY     P +        +    + +G        +G+ W D G  DS   A
Sbjct: 178 EILEYI----PEDSNFDFSKDLFPKLMASGIDLFGYNAKGY-WRDVGNPDSYRAA 227


>UniRef50_Q8SQX7 MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE n=3 Tax=Microsporidia
           RepID=Q8SQX7_ENCCU
          Length = 345

 Score =  217 bits (554), Expect = 2e-55,   Method: Composition-based stats.
 Identities = 60/248 (24%), Positives = 107/248 (43%), Gaps = 9/248 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +K +IL GG GTRL P+T  V K L+P  +KP++ + +  L+  GI+EI++      +  
Sbjct: 8   VKAVILVGGYGTRLRPLTYTVPKPLVPFANKPILRHQIEALVKVGIKEIILALNYYSEFI 67

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            + +    +E GI + Y+++  P G A    + + +L G     VL  +I      +  L
Sbjct: 68  IREVRDYSNELGISIVYSKEQEPLGTAGPLALAKKYLEGHTFF-VLNSDITCRFPLAEML 126

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFR-AISLEEKPKQPKSNWAVTGLYFYDSK 179
               +     T+    V DP R+G++  +++     S  EKPK   SN    G+Y  +  
Sbjct: 127 SFHYSHGREGTILSTNVDDPSRYGIIITEESTSLVRSFLEKPKDAVSNRVNAGIYILNPS 186

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           V++  +  + S   E+      +  L+  +L          W+D G     I+       
Sbjct: 187 VLDRIELRECSIEREIFPRMAEEHQLQVFDLK-------GFWMDIGQPADYIKGQGMYLR 239

Query: 240 VEKRQGFK 247
             +  G  
Sbjct: 240 HCQEAGID 247


>UniRef50_B0BZX4 Phosphoglucomutase/phosphomannomutase family Nucleotidyl
           transferase n=23 Tax=Bacteria RepID=B0BZX4_ACAM1
          Length = 844

 Score =  217 bits (553), Expect = 4e-55,   Method: Composition-based stats.
 Identities = 65/237 (27%), Positives = 110/237 (46%), Gaps = 11/237 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +++AGG GTRL P+T  + K ++PI ++P+  + +++L    I EI I T       
Sbjct: 1   MRAVLMAGGEGTRLRPLTCDLPKPMVPILNRPIAEHIVNLLKHHQIYEI-IATLYYLPDV 59

Query: 61  FQRLLGDGSEFGIQLEY-AEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK 119
            +    DGS+FG+Q+ Y  E+    G A         L    + LV+  +       +  
Sbjct: 60  MRDYFRDGSDFGVQMTYGIEEEQALGTAGCVKNISALLTD--TFLVISGDCITDFDLTAA 117

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYD 177
           ++    +   AT+   +V DP  FGVV  D + +     EKP   +  S+   TG+Y  +
Sbjct: 118 IKFHRQKGSKATLVLARVPDPMEFGVVITDQSHQICRFLEKPSTSEVFSDTVNTGIYILE 177

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
            +V++Y     PS++       +  + LE G      +  G+ W D G+ DS  EA 
Sbjct: 178 PEVLDYL----PSDQQTDFSKDLFPLLLEKGEPMFGYVAEGY-WCDVGSLDSYREAQ 229


>UniRef50_UPI0001C315BB Nucleotidyl transferase n=1 Tax=Conexibacter woesei DSM 14684
           RepID=UPI0001C315BB
          Length = 366

 Score =  216 bits (550), Expect = 7e-55,   Method: Composition-based stats.
 Identities = 75/267 (28%), Positives = 116/267 (43%), Gaps = 16/267 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +ILAGG GTRL P+T  V K ++P+ D+P I + L  L   G+ +++I       G 
Sbjct: 1   MQALILAGGEGTRLRPLTSTVPKPVVPLVDRPFIAFMLDWLRRHGVDDVVISCGFMASG- 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            + +LGDGS FGI+L Y E+P P G   A    E  L  +   LVL  ++      + +L
Sbjct: 60  VRNVLGDGSAFGIRLRYVEEPRPLGTGGAIKFAEPLL--DERVLVLNGDVLTDIDLTAQL 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
                     T+    V DP  +G+V  D++       EKP   Q  +N    G Y  + 
Sbjct: 118 AQHERTGARVTLALIAVDDPSAYGLVRRDEDGGVREFLEKPSPDQIDTNLVNAGAYVLER 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +V++      P+ER       +    +  G    E       WLD GT +  ++AS  + 
Sbjct: 178 EVLDAI----PTERAVSVEREVFPTLVRNGLYGYEA---SGYWLDIGTPERYLQASHDIL 230

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEG 265
                   + +  E    RN  + D  
Sbjct: 231 DGA----VETSVPEAFDSRNVAIADSA 253


>UniRef50_D1JGY1 Putative bifunctional protein glmU n=1 Tax=uncultured archaeon
           RepID=D1JGY1_9ARCH
          Length = 415

 Score =  215 bits (549), Expect = 9e-55,   Method: Composition-based stats.
 Identities = 67/236 (28%), Positives = 106/236 (44%), Gaps = 9/236 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +ILA G G R+ P+T    K +LPI  KP+I + L  +   GI + + +    D+  
Sbjct: 15  MKALILAAGEGKRMRPLTYERPKVMLPIAGKPIIEHLLEEVKEVGIDDFIFVVGYHDET- 73

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   G+G  + I LEY  Q +  G A A    E  +  +   ++ GD I   +     +
Sbjct: 74  IRDYFGNGERWDINLEYVTQKTQLGTADALRKAEELVENQ-FLMLNGDTIVSAKDIKKVI 132

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                      +   +V +PE +GVVE +   R   + EK + P SN    G+Y  D  +
Sbjct: 133 N----NGVNMVLGVIEVENPEDYGVVETEGE-RITEIHEKMRVPISNLVNAGVYALDKSI 187

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTF 236
                +   S+RGE E+T   Q+ +E+G     L  +   WLD      L+ A+ F
Sbjct: 188 FGVLSKTDKSKRGEFELTDSLQLLIESGEAI--LWEKIEHWLDLSYPWDLLTANEF 241


>UniRef50_B8LVX3 Mannose-1-phosphate guanylyltransferase n=2 Tax=Leotiomyceta
           RepID=B8LVX3_TALSN
          Length = 741

 Score =  215 bits (549), Expect = 1e-54,   Method: Composition-based stats.
 Identities = 56/252 (22%), Positives = 100/252 (39%), Gaps = 10/252 (3%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +IL GG GTRL P+T  + K L+   ++PMI + +  L  AG+ +I++          Q
Sbjct: 380 ALILVGGFGTRLRPLTLTLPKPLVEFGNRPMILHQVESLAAAGVTDIVLAVNYRPDIMVQ 439

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLN-GEPSCLVLGDNIFFGQGFSPKLR 121
            L     ++ I +E++ +  P G A    + E  L   +    VL  ++     F     
Sbjct: 440 ALKKYEEQYNINIEFSVESEPLGTAGPLKLAEKILGKDDSPFFVLNSDVICEYPFKQLAE 499

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNF--RAISLEEKPKQPKSNWAVTGLYFYDSK 179
              A  +  T+   +V +P ++GVV    N   R     EKP +   N    G+Y  +  
Sbjct: 500 FHKAHGDEGTIVVTKVDEPSKYGVVVHKPNHPSRIDRFVEKPVEFVGNRINAGIYILNPS 559

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           V++  +    S   E     + +  L + +L          W+D G     +  +    T
Sbjct: 560 VLKRIELRPTSIEQETFPAIVKEGQLHSFDL-------EGFWMDVGQPKDFLSGTCLYLT 612

Query: 240 VEKRQGFKIACL 251
              ++  K+   
Sbjct: 613 SLAKRNSKLLSP 624


>UniRef50_A6TTZ6 Nucleotidyl transferase n=1 Tax=Alkaliphilus metalliredigens QYMF
           RepID=A6TTZ6_ALKMQ
          Length = 825

 Score =  215 bits (548), Expect = 1e-54,   Method: Composition-based stats.
 Identities = 62/279 (22%), Positives = 113/279 (40%), Gaps = 14/279 (5%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K II+AGG GTRL P+T  + K ++PI +KP + Y + +L    I++I  +T        
Sbjct: 5   KAIIMAGGKGTRLKPLTCNIPKPMVPILNKPTMEYTVELLRKHNIKDIA-VTIAHLPTVI 63

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLR 121
                DG ++ + L Y  + +P G   +    E F+  + + +VL  +          + 
Sbjct: 64  TDYFHDGGKWDVNLSYYTEETPLGTGGSVKNAEEFI--DDTFIVLSGDSLTDINIKKAIE 121

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDSK 179
               +   AT+       P  +GVV  +DN R     EKP   +  SN   TG+Y  + +
Sbjct: 122 FHKNKGSKATLILKNEQMPIEYGVVITNDNGRITRFLEKPSWGEVFSNTINTGMYILEPE 181

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           V++Y +  +  +        +    LE        +   + W D G  +S  E    + +
Sbjct: 182 VLDYFQPGENFDF----SKDLFPKLLEDDIPMYGYVTEDY-WCDVGALNSYTETHFDILS 236

Query: 240 VEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
            +   G +   +E+      W+ +     +   +    Y
Sbjct: 237 GKVNIGLEGHQIED----GIWVGEGTQIGSGVKITPPVY 271


>UniRef50_A9A1Q3 Glucose-1-phosphate thymidyltransferase n=1 Tax=Nitrosopumilus
           maritimus SCM1 RepID=A9A1Q3_NITMS
          Length = 351

 Score =  215 bits (548), Expect = 1e-54,   Method: Composition-based stats.
 Identities = 89/237 (37%), Positives = 129/237 (54%), Gaps = 3/237 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKGIIL GG GTRL P+T    KQLLPI +KPM  Y +  +  AGI EI II        
Sbjct: 1   MKGIILHGGHGTRLRPLTHTGPKQLLPIANKPMSQYCIESMKNAGITEIAIIIGGIASKK 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   G+G +FG+++ Y  Q +P G+A A  + + F+  +   + LGDNI   +    K 
Sbjct: 61  VEEYYGNGEKFGVKITYISQEAPKGIAHAINLCKDFVKDDKFLVFLGDNILKKEILEYKT 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
            +       A +   +V +P +FG+ +  DN + I + EKPK P +N AVTG+YF + K+
Sbjct: 121 NY-ENSDADALLLLCEVDNPTQFGIADVKDN-KIIKIMEKPKDPPTNLAVTGIYFLNKKI 178

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
            E    +KPS R ELEIT   Q+ +E GN  +        W DTGT + ++ A+  +
Sbjct: 179 FEIIDILKPSWRNELEITDALQLLMEKGNKII-FDTVTDYWKDTGTPNDILHANKEI 234


>UniRef50_Q9KD03 Mannose-1-phosphate guanyltransferase n=1 Tax=Bacillus halodurans
           RepID=Q9KD03_BACHD
          Length = 249

 Score =  215 bits (548), Expect = 1e-54,   Method: Composition-based stats.
 Identities = 64/241 (26%), Positives = 115/241 (47%), Gaps = 10/241 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+ILAGG GTRL P+T  + K +LPI   P + + L+ L   GIR+I+++        
Sbjct: 1   MKGVILAGGRGTRLKPLTDQIPKPMLPIAGVPCLAHGLAHLAAHGIRDIVMLV-HYLNHQ 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +    DGS++G+++ Y ++ +P G A +    E +L  +   +V+  ++         +
Sbjct: 60  MKAYFQDGSKYGMRITYVQEDAPLGTAGSLKAAERYL--DEPFVVMSGDVLTTISIQEAI 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSN--WAVTGLYFYDS 178
                +    T+   +V + + +GVV+   N R ++  EKP + K+      TGLY  D 
Sbjct: 118 VFHKRQNSLMTMLTKRVKNGQNYGVVQTGPNHRVVAFREKPTEDKTREVLVNTGLYVMDP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
            V+ Y  +    + G+  I  +    L+     +  L  G  W D G+    ++A+  V 
Sbjct: 178 FVLSYIPKGSAVDLGKDVIPYLVDRKLD-----IFALEGGGYWRDIGSFHDYLQANNDVN 232

Query: 239 T 239
           +
Sbjct: 233 S 233


>UniRef50_Q0W4J0 Glucose-1-phosphate thymidylyltransferase n=2 Tax=Euryarchaeota
           RepID=Q0W4J0_UNCMA
          Length = 400

 Score =  215 bits (548), Expect = 1e-54,   Method: Composition-based stats.
 Identities = 71/279 (25%), Positives = 131/279 (46%), Gaps = 12/279 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++LA G G+RL P T    K ++P+ +KP++ Y ++ L  +GI +I+++   + +  
Sbjct: 1   MKAVVLAAGEGSRLKPFTATRPKVMIPVGNKPILEYVINALQESGIIDIVMVVGYK-REK 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                GDG ++G+ + Y EQ    G A A       +  +   ++ GD +         +
Sbjct: 60  IMDYFGDGHKWGVNITYVEQFQQLGTAHALRQASHLIK-DHFLVINGDTVIDASAIKEII 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPK-SNWAVTGLYFYDSK 179
           ++   +   AT+    V   + +GVVE  +N     +EEKPK  +  N    G+Y +  K
Sbjct: 119 KY---KVGDATMLTVSVDKAQAYGVVETQNNL-VKGIEEKPKYKEAGNIVNAGVYCFSPK 174

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           V ++ + +  SERGE E+T   +  +E+ N +V  +     W+D     +LI+ +     
Sbjct: 175 VFDFLEYMDISERGEYEVTDAIRKMIES-NYSVRAVHTSALWMDAVYLWNLIDLNAATLA 233

Query: 240 VEKRQGFKIACLEEIAWRNG--WLDDEGVKRAASSLAKT 276
             K +      +EE A   G  ++ +  V R+ S +   
Sbjct: 234 GRKPENH--GTVEEGARILGPVYIGENTVIRSGSYIVGP 270


>UniRef50_B3QV42 Nucleotidyl transferase n=1 Tax=Chloroherpeton thalassium ATCC
           35110 RepID=B3QV42_CHLT3
          Length = 847

 Score =  215 bits (547), Expect = 2e-54,   Method: Composition-based stats.
 Identities = 65/280 (23%), Positives = 118/280 (42%), Gaps = 14/280 (5%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K II+AGG GTRL P+T  + K L+P+  +PM+++   +L   G++EI  +   + +   
Sbjct: 12  KAIIMAGGFGTRLRPLTMNIPKPLVPMMQRPMMHHIAELLKKYGVKEITSMLYYQPES-I 70

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLR 121
           +   GDG +FG ++ Y    +  G A +      F++G    +V+  ++      S  + 
Sbjct: 71  REYFGDGKKFGYKMHYILSDADYGTAGSVRNAYDFVDGR--FVVISGDVLTDFDLSKAIE 128

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDSK 179
               R   AT+    V +P +FGVV  D + R     EKP   +  S+   TG+Y  + +
Sbjct: 129 FHVKRGALATMVLTHVKNPLQFGVVITDKDGRITRFLEKPTWGEVFSDTINTGIYILEKE 188

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ- 238
           V++      P +        +    L+        +  G+ W D GT     EA      
Sbjct: 189 VMDLI----PYKEDYDFSKDLFPKMLKENMPLYGYISNGY-WRDVGTLTEYQEAHIDCLN 243

Query: 239 ---TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAK 275
               ++    ++    +  A ++  +D   VK +      
Sbjct: 244 GKVNLDFTYDYEKIADDVYAHKSAKVDLNSVKFSGKVYIG 283


>UniRef50_Q7NNE0 Mannose-1-phosphate guanyltransferase n=5 Tax=Gloeobacter violaceus
           RepID=Q7NNE0_GLOVI
          Length = 327

 Score =  214 bits (546), Expect = 2e-54,   Method: Composition-based stats.
 Identities = 64/236 (27%), Positives = 105/236 (44%), Gaps = 9/236 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK  +LA G GTRL P T  + K L+P+ +KP++ + L++    G  +I+       +  
Sbjct: 1   MKAFVLAAGKGTRLRPFTDALPKPLMPVVNKPVMTHILALCRKHGFDQIVANLHYRGEKI 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +R   DG   G++L Y+ +    G A        FL G+ + LV+  ++         +
Sbjct: 61  AER-FADGHRHGVELRYSWEEQLLGTAGGVRRQADFLAGD-AFLVISGDVMTDLDLGALV 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQ--PKSNWAVTGLYFYDS 178
           R        AT+   +V DP RFGVV  D + R  S +EKP +   +S  A TG+Y  + 
Sbjct: 119 RFHKQSGAVATMAVKEVGDPSRFGVVLTDPDGRVESFQEKPAKGSERSRLANTGIYVLEP 178

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
           +V E+  +    + G      +  + +  G   V  +  G  W D GT    +   
Sbjct: 179 EVFEHIPEAAFFDFG----NDLFPLLVSKGAP-VYAMRTGAYWSDVGTLSQYLYTH 229


>UniRef50_C6A0S3 Nucleotidyl transferase family n=6 Tax=Thermococcaceae
           RepID=C6A0S3_THESM
          Length = 361

 Score =  214 bits (545), Expect = 3e-54,   Method: Composition-based stats.
 Identities = 62/240 (25%), Positives = 109/240 (45%), Gaps = 11/240 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M  +ILAGG GTRL P+T    K ++P ++KPM+ Y +  L+ AG+ EI I+     +  
Sbjct: 1   MHAVILAGGKGTRLLPLTVYRPKPMIPFFNKPMMEYVVRELVNAGVEEIFILVGYLKERI 60

Query: 61  FQRLLGDGSEFGIQLEYAE-QPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK 119
                GDGS+FG++++Y+  +    G A A       +N   + +V   ++         
Sbjct: 61  I-NYFGDGSDFGVEIKYSNGENIKLGTAGATKKVADRIND--TFIVASSDVLTNLDIKTL 117

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYD 177
             +   +   AT+   +V DP ++G+   D N R +  +EKP  ++  SN    G+Y ++
Sbjct: 118 YDYHKRKKALATIALSRVEDPSQYGIAIVDSNNRILKFKEKPRLEEAFSNLVNAGVYIFE 177

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
            +V +      P  +      ++    LE            + W D G   S ++A+  V
Sbjct: 178 PEVFDLV----PRGQNFDFSLNLFPKMLEENLPLYGFPFEEY-WNDVGRPSSYLQATADV 232


>UniRef50_C0E9C6 Putative uncharacterized protein n=1 Tax=Clostridium methylpentosum
           DSM 5476 RepID=C0E9C6_9CLOT
          Length = 768

 Score =  214 bits (544), Expect = 4e-54,   Method: Composition-based stats.
 Identities = 59/281 (20%), Positives = 106/281 (37%), Gaps = 18/281 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +I+AGG G+RL P+T  + K L P+  +P++ Y L +L        ++    +    
Sbjct: 1   MQAVIMAGGEGSRLRPLTCDIPKPLAPLCGRPVLEYILDLLAEHRFDRAVMTLLYQGNKI 60

Query: 61  FQRLLGDGSEF-GIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK 119
                 DG ++ GI+L Y+ +P P G A +        +     LV+  +       +  
Sbjct: 61  ISHF--DGEDYKGIELSYSFEPQPLGTAGSVRHA--VKDPRDDILVISGDALCDFDLTKA 116

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYD 177
           +         AT+   +V DP  +G+V   +N R     EKP      ++ A TG+Y   
Sbjct: 117 VAFHRQSRAAATLLVKRVEDPREYGLVNVTENGRIAGFLEKPSLSHCVTDLANTGIYILS 176

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
             V +  ++ K  +  +     +    LE           G+ W D G   S +     +
Sbjct: 177 PAVFDLIEEGKKVDFAQQ----VFPKMLEKKMPLYAYEDAGY-WCDIGDLQSYVNCQRDM 231

Query: 238 QTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
                    K+ C  +     G      +  A  ++    Y
Sbjct: 232 LQ------GKVRCSIDAPEVGGVFTKTELLSAQGAVRPPAY 266


>UniRef50_C0GGS0 Nucleotidyl transferase n=1 Tax=Dethiobacter alkaliphilus AHT 1
           RepID=C0GGS0_9FIRM
          Length = 385

 Score =  213 bits (543), Expect = 6e-54,   Method: Composition-based stats.
 Identities = 63/240 (26%), Positives = 109/240 (45%), Gaps = 10/240 (4%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K +ILA G GTRL P+T  VSK ++ + ++P + + + +L   G+++I ++         
Sbjct: 32  KAMILAAGLGTRLRPLTNSVSKPMVEMANRPCMEHAVRLLAKYGVKDI-VVNLHYMPEII 90

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLR 121
           Q   GDGS FG+ + Y+ +    G A  F   + F   EP  L++  +           +
Sbjct: 91  QEHFGDGSAFGVNITYSYEKELMGTAGGFKRVQKFFGDEP-ALIISGDALTDVNLEQLYK 149

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDSK 179
                   AT+   QV DP ++GVV  + N + +  +EKP  ++  SN A TG+Y +D +
Sbjct: 150 FHKENEAIATLALKQVADPTQYGVVVREGN-KIVQFQEKPKLEEAISNLANTGIYLFDPR 208

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           + ++       + G      +    LE G      + + + W D G      EA   + T
Sbjct: 209 IFDHIPADTFYDFG----KQVFPELLEKGEKMCGYVMKEY-WCDVGDLTMYREAHYDMLT 263


>UniRef50_A6CNU8 Mannose-1-phosphate guanyltransferase (Pyrophosphorylase domain and
           phosphomannomutase domain) n=1 Tax=Bacillus sp. SG-1
           RepID=A6CNU8_9BACI
          Length = 345

 Score =  213 bits (543), Expect = 6e-54,   Method: Composition-based stats.
 Identities = 65/256 (25%), Positives = 107/256 (41%), Gaps = 10/256 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+ILAGG GTRL P T  V K ++ I +KP++ Y +++L   GI  I+I T  +    
Sbjct: 1   MKGVILAGGKGTRLKPYTLTVPKPMVTIMNKPILEYNIALLKANGITSIMITTCYK-ADK 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                GDGSEFG+ + Y  +  P G A        +LN     +V+  + F        +
Sbjct: 60  ISEYFGDGSEFGVDITYFHEDFPLGTAGGVFESSHYLN--EPFVVISGDAFTTLSLRDAI 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
                +    T+ G ++ DP  +GV + D   R I   EKP+  +  S    TG+Y    
Sbjct: 118 EFHQLKGSPLTIVGKEMEDPRGYGVCKTDSEGRLIEFAEKPESGEINSKLVNTGIYVIQP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +++       P E        +    +   +  + +      W D G  +    A     
Sbjct: 178 ELLRKY----PFEGNIDFSRDVFPRMIREQD-NIYVFETEDYWRDIGNPEQYKLAREDYL 232

Query: 239 TVEKRQGFKIACLEEI 254
             + ++      +EE+
Sbjct: 233 NGKMKEKAGADSIEEV 248


>UniRef50_UPI0001693120 glucose-1-phosphate thymidyltransferase n=1 Tax=Paenibacillus
           larvae subsp. larvae BRL-230010 RepID=UPI0001693120
          Length = 338

 Score =  213 bits (542), Expect = 7e-54,   Method: Composition-based stats.
 Identities = 76/244 (31%), Positives = 128/244 (52%), Gaps = 4/244 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+IL  G GTRL P T    K +LP+  +P+I   ++ ++  GI EI I+     +G 
Sbjct: 1   MKGLILCAGQGTRLQPFTYARPKCMLPVNGEPVIVSIINKMVHIGICEIGIVIN-ASQGQ 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
              +LG G  +   L Y  Q +  GLA A     +F+ GEP  L+LGDN+  G    P +
Sbjct: 60  IPAMLGSGEAYRCSLTYLLQENSLGLADAVKSAYSFIQGEPFLLILGDNLIEG-SIMPLI 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
             + +    A++    V +P +FGV +   N + + LEEK + P S+ AV G Y ++S +
Sbjct: 119 DFLGSEKADASLLLAHVKNPHQFGVADVSIN-KVVRLEEKSQNPSSDLAVVGAYAFNSDI 177

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            +   +++PS+RGE E+T   Q+ ++ G      +     + D GT +  ++A+ +  + 
Sbjct: 178 WKILDRLEPSKRGEYELTDAIQLLIDQGKHVAYCITTE-PFFDIGTPERWLDANRYKVSK 236

Query: 241 EKRQ 244
           + R+
Sbjct: 237 DSRK 240


>UniRef50_Q8DLP2 Mannose-1-phosphate guanyltransferase n=9 Tax=Cyanobacteria
           RepID=Q8DLP2_THEEB
          Length = 843

 Score =  212 bits (541), Expect = 8e-54,   Method: Composition-based stats.
 Identities = 59/254 (23%), Positives = 113/254 (44%), Gaps = 14/254 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +++AGGSGTRL P+T  + K ++P+ ++P+  + L++L    + ++++ T       
Sbjct: 1   MRVVVMAGGSGTRLRPLTCDLPKPMVPVVNRPIAEHILNLLRRHNLDDVVM-TLHYLPDV 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPS-PDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK 119
            +   GDG+EFG+ L Y  +   P G A +       L  +P  +V GD+I      +  
Sbjct: 60  VRDYFGDGNEFGVHLSYVVEEEQPLGTAGSVKNIVNLLT-DPFLVVSGDSI-TDVDLTDA 117

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYD 177
           LR         T+   +V  P+ FG+V  D + R     EKP   +  ++   TG+Y  +
Sbjct: 118 LRFHQQHGAPVTLILARVPQPKEFGIVFTDSDGRVRRFLEKPSAAEVFTDTVNTGIYILN 177

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
             V++Y       +        +  + L+A       +   + W D G+  +  +     
Sbjct: 178 PTVMDYLNSGIERDF----SRDLFPLLLQADVPMYGYITDAY-WCDVGSLQTYQQVQQDA 232

Query: 238 ---QTVEKRQGFKI 248
              +   + QG ++
Sbjct: 233 LYGRVHLEIQGHEV 246


>UniRef50_A6Q9R9 Mannose-1-phosphate guanylyltransferase n=3 Tax=Bacteria
           RepID=A6Q9R9_SULNB
          Length = 840

 Score =  212 bits (540), Expect = 1e-53,   Method: Composition-based stats.
 Identities = 69/263 (26%), Positives = 121/263 (46%), Gaps = 15/263 (5%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K +++AGG GTR+ P+T  + K +LPI + PM+ + +  L+  GI EI+++         
Sbjct: 6   KAVMMAGGFGTRIQPLTHSMPKPMLPICNIPMMEHTMRKLVDIGITEIVVLL-YFKPEII 64

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLR 121
           +   GDGS  G++LEY       G A A      FL  + + +++  ++     F   + 
Sbjct: 65  KNHFGDGSRIGVKLEYVLPEEDLGTAGAVGAAREFL--DTTFIIVSGDLVSDFDFEKIID 122

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDSK 179
           H        T+    V +P +FGVV  D+N +     EKP   +  S+   TG+Y  + +
Sbjct: 123 HHYKTESKLTITLTSVENPLQFGVVIADENGKIEKFLEKPSWGEVFSDTINTGIYVIEPE 182

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           +++Y     P+E        +  + +  G   +    RG+ W D G  DS  E    +  
Sbjct: 183 ILDYI----PTEDNFDFAKDLFPLLMSEGIDLMSYDARGY-WRDVGNPDSYREVYGDIF- 236

Query: 240 VEKRQGFKIACL-EEIAWRNGWL 261
              +Q  K+A   ++I + +G L
Sbjct: 237 ---KQKIKVAFPGKKIEYPDGVL 256


>UniRef50_A7AUL2 Mannose-1-phosphate guanyltransferase, putative n=1 Tax=Babesia
           bovis RepID=A7AUL2_BABBO
          Length = 417

 Score =  211 bits (537), Expect = 2e-53,   Method: Composition-based stats.
 Identities = 56/247 (22%), Positives = 94/247 (38%), Gaps = 11/247 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +ILAGG GTRL P+T  V K ++P  ++P++ Y +     AG+  I++  + E    
Sbjct: 1   MKCVILAGGHGTRLRPLTLTVPKPMIPFCNRPIVEYQIKASKEAGVDHIILAISHEQNNM 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPS----CLVLGDNIFFGQGF 116
              +        I+++ + +    G A    + +  +          LVL  +I     F
Sbjct: 61  VPMIKELSERCNIRIDCSIEKESLGTAGPLKLAKNLICDPADNCKEFLVLNSDIICSYPF 120

Query: 117 SPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFY 176
           +  +         AT+   +   P  FGV+  D+ +R     EKP Q  SN    G+Y  
Sbjct: 121 AEMISAHRKNNADATILVTKTTHPSDFGVIVHDETYRIHEFVEKPSQFISNQINAGIYVL 180

Query: 177 DSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTF 236
           +  +++Y      S         +    +  G      L     W D G     I A   
Sbjct: 181 NKNMLDYIPDGSVSIE-----RYLFPTMVAMGRTYCHPL--NGLWADIGKPSDYIRAQQL 233

Query: 237 VQTVEKR 243
             T   +
Sbjct: 234 YLTGRPK 240


>UniRef50_B0K747 Nucleotidyl transferase n=10 Tax=Thermoanaerobacteraceae
           RepID=B0K747_THEP3
          Length = 776

 Score =  210 bits (536), Expect = 3e-53,   Method: Composition-based stats.
 Identities = 60/249 (24%), Positives = 109/249 (43%), Gaps = 12/249 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKGII+AGG G+RL P+T  + K ++P+ +KP I + +  L   GI++ L +T       
Sbjct: 1   MKGIIMAGGEGSRLRPLTADIPKPMVPVANKPAIKHIVEHLHKYGIKD-LAVTLFYLPQK 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            ++ L    E+G ++++  +  P G A +      FLN   + +V+  ++          
Sbjct: 60  IKKYLE--EEYGDEIKFYIEDKPLGTAGSVKNARDFLND--TFIVMSGDVITDVNIKEAY 115

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
                +    T+   +V  P  +GVV  D+  +     EKP   +  S+   TG+Y  + 
Sbjct: 116 EFHRKKGAKVTLILTRVDVPLEYGVVIVDEEGKIKKFLEKPSWGEVFSDTVNTGIYIIEP 175

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +++E+  Q KP +        +  M L+        +  G  W D G  +  I +   + 
Sbjct: 176 EILEFIPQDKPFDF----SKDLFPMLLKNDIPMYGYI-TGGYWCDIGNTNQYITSHFDIL 230

Query: 239 TVEKRQGFK 247
                 G+K
Sbjct: 231 EGRVDLGYK 239


>UniRef50_C6A1S5 NDP-sugar synthase n=9 Tax=Thermococcaceae RepID=C6A1S5_THESM
          Length = 413

 Score =  210 bits (536), Expect = 4e-53,   Method: Composition-based stats.
 Identities = 66/266 (24%), Positives = 116/266 (43%), Gaps = 20/266 (7%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +ILAGG GTRL P++    K ++P+  +P + Y L  L      + +I++    +G 
Sbjct: 1   MKAVILAGGFGTRLRPLSSTRPKPMIPVLGRPNLQYILENLQKISEIDEVILSVHYMRGE 60

Query: 61  FQRLLGDG-SEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK 119
            +  + D  S++   + +   P P     A    E  ++ E   LV+  ++F    F   
Sbjct: 61  IREFIEDKMSDYPKDIRFINDPMPLETGGALKNVEDVVSDE--FLVIYGDVFTNFNFEEL 118

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSK 179
           ++   A     TV   +V DPE++GVV  D+  + +  EEKP +PKSN    G+Y  + +
Sbjct: 119 IKAHKANDALITVALTKVYDPEKYGVVVTDEEGKIVDFEEKPLRPKSNLIDAGIYMVNKE 178

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           ++       P  +       +   ++  G     ++ R   W+D GT +    A   +  
Sbjct: 179 ILNEI----PKGKEIYFEREVLPKFVAQGLAHGYMMPRNNYWVDLGTPEDFFYAHQLI-- 232

Query: 240 VEKRQGFKIACLEEIAWRNGWLDDEG 265
                      L+EIA  NG+   + 
Sbjct: 233 -----------LDEIAKNNGYYTVKE 247


>UniRef50_A8LZU8 Glucose-1-phosphate thymidyltransferase n=15 Tax=Actinomycetales
           RepID=A8LZU8_SALAI
          Length = 353

 Score =  209 bits (533), Expect = 8e-53,   Method: Composition-based stats.
 Identities = 78/239 (32%), Positives = 124/239 (51%), Gaps = 3/239 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++L+GG GTRL P T  + KQL P+ ++P++ + L  +   G+ E+ I+        
Sbjct: 1   MKALVLSGGMGTRLRPFTHSMPKQLFPVANQPVLAHVLGKIRTLGVTEVGIVVGGGGAAQ 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  +GDG+ FG+Q+ Y  Q  P GLA A  +   FL  +   + LGDN+   +G    +
Sbjct: 61  VEEAIGDGARFGLQVTYVHQHQPRGLAHAVQVAADFLGTDDFLVYLGDNVLT-EGLVEFV 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                    A +   +V DP  +GVVE D   R   L EKP  P+S+ A+ G+Y +  ++
Sbjct: 120 ARFRDERPAAHLLVQKVSDPRSYGVVELDA-GRVQRLVEKPASPRSDLAIVGVYLFTHEI 178

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
               ++++P  RGELE+T   Q  +++G   VE    G  W D G  D L+E +  + T
Sbjct: 179 HTAIREIRPGRRGELELTDAVQWLVDSGAR-VEATEYGGNWSDVGQVDDLLECNRHLLT 236


>UniRef50_Q0AV26 Mannose-1-phosphate guanyltransferase n=1 Tax=Syntrophomonas wolfei
           subsp. wolfei str. Goettingen RepID=Q0AV26_SYNWW
          Length = 343

 Score =  209 bits (532), Expect = 1e-52,   Method: Composition-based stats.
 Identities = 54/236 (22%), Positives = 108/236 (45%), Gaps = 10/236 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +I+A G G+RL P+T+   K ++P+ ++P++   + +L     +E++     + +  
Sbjct: 1   MKAMIMAAGVGSRLMPLTKDTPKPMVPMTNRPLMENIVELLGRHHFKEVIANLHHQGES- 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                 DG +FG++L Y+ +    G A      E FL  + + +V+  +       S  L
Sbjct: 60  ISGYFDDGHDFGLKLLYSPEEVLLGTAGGVKKCEWFL--DETFVVISGDALTDMDLSELL 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDS 178
                R   AT+   +V + E+FGVV   ++ R    +EKP  ++  S+ A TG+Y ++ 
Sbjct: 118 AQHRKRGALATIALKEVENVEQFGVVLTAEDGRISRFQEKPGREEALSHQANTGIYVFEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
           ++ +Y    +  + G      + +M           +     W D G  ++  +A+
Sbjct: 178 EIFKYIPAAQFYDFGCQLFPQLVEM-----GAPFYAVSTQDYWCDVGNIETYRQAN 228


>UniRef50_B3LAG9 Mannose-1-phosphate guanyltransferase, putative n=3 Tax=Plasmodium
           RepID=B3LAG9_PLAKH
          Length = 434

 Score =  209 bits (531), Expect = 1e-52,   Method: Composition-based stats.
 Identities = 66/284 (23%), Positives = 113/284 (39%), Gaps = 12/284 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M  +IL GG GTRL P+T    K L+   +KP++ + +  L   GIREI++    +    
Sbjct: 1   MNALILVGGYGTRLRPLTLTTPKPLISFCNKPILEHQIFNLARCGIREIILAIAYKPTDI 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
              +     ++ +++ Y+ +  P G      + E +L+      V   +I         +
Sbjct: 61  TNFVDNLEKKYNVKIIYSIEEEPLGTGGPIKLAEKYLSKYDDFFVFNSDIICSFPLLEMM 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                     T+   +V DP  FGVV  ++N R    EEKP+ PKS+    G+Y  + KV
Sbjct: 121 SFHKQSNAPLTILVKEVEDPRAFGVVITEEN-RITKFEEKPQVPKSSLINAGIYIMNRKV 179

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTH-DSLIEASTFVQT 239
           +        S   E     I         L   +L +   W D G   D L   + +++ 
Sbjct: 180 LNRIPMRNTSLEKE-----IFPQLANENMLYFYVLNK--FWADIGKPMDFLKGQALYMED 232

Query: 240 VEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLL 283
           +++ +G  I    EI      +D   V        ++    + L
Sbjct: 233 LKENRGKGIEEKREIDKE---IDTAKVSATKPFKEESILRDHFL 273


>UniRef50_Q8ILP1 Mannose-1-phosphate guanyltransferase, putative n=4 Tax=Plasmodium
           RepID=Q8ILP1_PLAF7
          Length = 408

 Score =  207 bits (528), Expect = 2e-52,   Method: Composition-based stats.
 Identities = 60/248 (24%), Positives = 101/248 (40%), Gaps = 9/248 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M  +IL GG GTRL P+T    K L+   +KP+I + +  L   GI+EI++    +    
Sbjct: 1   MNALILVGGYGTRLRPLTLTTPKPLINFCNKPIIEHQILHLAKCGIKEIILAIAYKPTNI 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
              +     ++ +Q+ ++ +  P G      + E +LN      V   +I         +
Sbjct: 61  TNFVKEMEKKYNVQIIFSVEDEPLGTGGPLKLAENYLNKYDDFFVFNSDIICTFPLIEMM 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                     T+   +V DP  FGVV  +D       EEKP  PKS+    G+Y  + ++
Sbjct: 121 NFHKQNKAPLTILVKEVEDPRAFGVVITEDKM-ITKFEEKPLVPKSSLINAGIYILNKQI 179

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTH-DSLIEASTFVQT 239
           + +  Q   S   E+     +   L               W D G   D L   S +++ 
Sbjct: 180 LNFIPQRNCSLEKEIFPKLASDNML-------YFYQLNNFWADIGKPLDFLKGQSLYMEN 232

Query: 240 VEKRQGFK 247
           +E+R+  K
Sbjct: 233 LEERKYEK 240


>UniRef50_B0BLL5 dTDP-1-glucose synthase n=1 Tax=Actinomadura madurae
           RepID=B0BLL5_9ACTO
          Length = 344

 Score =  207 bits (528), Expect = 3e-52,   Method: Composition-based stats.
 Identities = 77/257 (29%), Positives = 122/257 (47%), Gaps = 4/257 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++LAGG+ +RL P +  + KQL+P+  +P++ + L  +   G+R+  I+        
Sbjct: 1   MKALVLAGGTASRLRPFSNSLPKQLIPLAGRPVLEHVLRGIADIGVRDTAIVVGDTAPA- 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
               +GDG+  G+++ Y  Q  P GLA    +   FL  +   + LGDN+  G    P  
Sbjct: 60  VMDAIGDGARLGLRVTYVPQARPLGLAHCVTLARPFLGDDDFVMYLGDNLLPGGIAGPA- 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           R    R   A +   +V DP  FGV E   +     LEEKP  P+++ AV G+YF+ S V
Sbjct: 119 RRFRDRRPSAQLLLRRVADPRAFGVAEVGRDGVVRRLEEKPAHPRTDLAVLGVYFFTSAV 178

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTF-VQT 239
                  +PS RGELEIT   Q+ ++ G  TV  +     W D G    ++  +   +  
Sbjct: 179 HAAIDACRPSHRGELEITDAIQVLIDRGR-TVRAVEHTGHWRDIGRPADVLACNRRLLAE 237

Query: 240 VEKRQGFKIACLEEIAW 256
           +  R    +    E+  
Sbjct: 238 LRPRTDGDLDAATEVTG 254


>UniRef50_Q46AY5 Glucose-1-phosphate thymidylyltransferase n=4
           Tax=Methanosarcinaceae RepID=Q46AY5_METBF
          Length = 405

 Score =  207 bits (526), Expect = 5e-52,   Method: Composition-based stats.
 Identities = 66/256 (25%), Positives = 117/256 (45%), Gaps = 8/256 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK IILA G G R  P+T   SK +LPI ++P++ + +  L   GI +I++I   + K  
Sbjct: 1   MKAIILAAGEGLRCRPLTLTRSKVMLPIANRPILEHVIGSLEKNGITDIILIVGYK-KER 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEP--SCLVLGDNIFFGQGFSP 118
                 DG  FG++++Y EQ +  G A A    + ++  E     ++ GDN+   +  + 
Sbjct: 60  IMDYFEDGLNFGVKIKYVEQKAQLGTAHAIEQAKKWIEPEDSEFLVLNGDNLVEPKTIAD 119

Query: 119 KLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDS 178
            L +       A++   Q+ +   +GVV   +  R   + EK     S    TG+Y +  
Sbjct: 120 LLNNYE---GDASLLTVQMEETAGYGVV-LKEKKRVTRILEKRPGDLSRIVNTGIYIFTP 175

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +V E  ++   SE GE  IT   Q+ ++ G +   +  +   W+D      L++A+  V 
Sbjct: 176 QVFETIEKTPISENGEYAITDTLQLMIDEGKIVTSVSTKS-KWIDAVHSWDLLKANAIVL 234

Query: 239 TVEKRQGFKIACLEEI 254
              +    +    E +
Sbjct: 235 NSARNLKLEGEVEEGV 250


>UniRef50_D2RY68 Nucleotidyl transferase n=2 Tax=Halobacteriaceae RepID=D2RY68_9EURY
          Length = 248

 Score =  206 bits (524), Expect = 7e-52,   Method: Composition-based stats.
 Identities = 68/239 (28%), Positives = 116/239 (48%), Gaps = 5/239 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ ++LA G GTRL P+T    K L+ + DKP+I      L+  G+ +I+++   + +  
Sbjct: 1   MQAVVLAAGKGTRLRPLTDDKPKVLVEVNDKPLIEDVFDNLLEIGVNDIVVVVGYQKEQI 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +R  GD  E G+ + YA Q    GLA A +  E  +  E   L+LGDN+F G       
Sbjct: 61  IERY-GDEYE-GVPITYAHQRKQLGLAHAILQAEPHI-DEDFVLMLGDNVFRGNLGDVVN 117

Query: 121 RHVAARTEGATVF-GYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSK 179
           R    R + A +       +  R+GV++ ++    + + EKP  P SN  +TG Y +   
Sbjct: 118 RQQEDRADAAFLVEEVPYEEASRYGVLDTNEYGEIVEVVEKPDDPPSNLVMTGFYTFTPA 177

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +      V+PS+RGE E+     + +++G  T++ +      +D G  +    A   +Q
Sbjct: 178 IFHACHLVQPSDRGEYELPDAIDLLIQSGR-TIDAIRMDGWRIDVGYPEDREAAEERLQ 235


>UniRef50_Q74B34 Nucleotidyltransferase family protein n=1 Tax=Geobacter
           sulfurreducens RepID=Q74B34_GEOSL
          Length = 476

 Score =  205 bits (521), Expect = 2e-51,   Method: Composition-based stats.
 Identities = 65/237 (27%), Positives = 104/237 (43%), Gaps = 13/237 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +++AGG G RL P+T  V K +LP+ D+P++   +  L  +GIRE+ + T        +
Sbjct: 249 AVVMAGGYGKRLLPLTEQVPKPMLPVGDRPLLERTIDQLRRSGIREVNLTTHYLPDSIVE 308

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
              GDG  FG++L Y ++  P G A    + +         LV+  +I  G  F     +
Sbjct: 309 H-FGDGDSFGVKLNYLKEDHPLGTAGGLKLMK---KASDPFLVMNGDILTGVPFQEMFAY 364

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
                   TV   +      FGVVE DD  R   L+EKP    + +   G+Y  +  V +
Sbjct: 365 HRKNGAEITVGVRKYEVQVPFGVVECDD-VRITGLKEKPS--LTFFINAGIYLLEPSVCD 421

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
                   E    ++T + Q  L+ G   V      + WLD G H+   +A   V++
Sbjct: 422 LIP-----EGERFDMTDLIQKLLDEGRSVVSFPIMEY-WLDVGRHEDYQKAQEDVRS 472


>UniRef50_B0PFA5 Putative uncharacterized protein n=1 Tax=Anaerotruncus colihominis
           DSM 17241 RepID=B0PFA5_9FIRM
          Length = 772

 Score =  205 bits (521), Expect = 2e-51,   Method: Composition-based stats.
 Identities = 60/241 (24%), Positives = 94/241 (39%), Gaps = 10/241 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +I+AGG GTRL P+T    K +  +  +P++ Y L +L   G+ E  ++T       
Sbjct: 1   MKAVIMAGGRGTRLRPLTERCPKPMARLCGRPVVEYILELLAKNGVTES-VLTLQYLPDQ 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                 D S  GI L + E+  P G A +       +  +   LV+  +          +
Sbjct: 60  IVSHFPDNSFAGIALSFCEEAQPLGTAGSVKNAAGQIGED--LLVISGDALCDFSLREAM 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
              AAR    T+   +V DP  +G+V  D +       EKP   Q  S  A TG+Y    
Sbjct: 118 DQHAARCADVTIVTARVGDPREYGLVIADSDGHVTGFIEKPSFAQATSELANTGIYILSP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
             VE     +  +        +    LE G + V+       W D G  ++   A   + 
Sbjct: 178 HAVEMIPDGQIFDFA----ADLFPRMLEKG-MAVDCCTLSGYWCDIGDLEAYRRAQADLL 232

Query: 239 T 239
            
Sbjct: 233 A 233


>UniRef50_A6UUQ4 Glucosamine-1-phosphate N-acetyltransferase n=6 Tax=Methanococcales
           RepID=GLMU_META3
          Length = 411

 Score =  204 bits (519), Expect = 3e-51,   Method: Composition-based stats.
 Identities = 61/237 (25%), Positives = 119/237 (50%), Gaps = 14/237 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M  +IL  G GTRL P+T  + K +LP+   P++   ++ +    +  I +I   E    
Sbjct: 1   MDAVILCAGKGTRLMPLTENIPKPMLPVGGAPILERIINKIDKL-VENIYLIVKYE---- 55

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            + ++ +  +   ++++ EQ   DG   A ++ +  ++G+   LV+  +I F    +  +
Sbjct: 56  -KEIIINHFKNNDKIKFIEQTDIDGTGYAVLMAKNHISGD--FLVINGDIIFDDDLTNIV 112

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                      +   +V +P  FGV+  D+    I L+EKPK PKSN    G+Y +++K+
Sbjct: 113 NDDVKN----IITLNEVDNPSNFGVIVVDNQNNIIELQEKPKNPKSNLINAGIYKFENKI 168

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
            +  + ++PSERGE+E+T   +  ++  N  ++ +     W D G    L++A+T +
Sbjct: 169 FDILETLRPSERGEVELTDAIKELIKENN--IKGIKLNGYWNDIGKPWDLLDANTHI 223


>UniRef50_C8NLU6 Mannose-1-phosphate guanyltransferase n=88 Tax=Actinomycetales
           RepID=C8NLU6_COREF
          Length = 372

 Score =  204 bits (519), Expect = 3e-51,   Method: Composition-based stats.
 Identities = 55/236 (23%), Positives = 100/236 (42%), Gaps = 7/236 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +  +IL GG GTRL P+T    K +LP    P + + L+ +  AGI  +++ T+ + +  
Sbjct: 20  VDAVILVGGKGTRLRPLTNNTPKPMLPTAGHPFLKHLLARIKAAGITHVVLGTSFKAE-V 78

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F+   GDGS+ G+++EY  +  P G           L  + + +V   ++  G      L
Sbjct: 79  FEDYFGDGSDLGLEIEYVVEDQPLGTGGGIRNVYDKLRHD-TAVVFNGDVLSGADLGDIL 137

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                +    T+   +V +P  FG V  D + R +   EK + P ++    G Y +  ++
Sbjct: 138 ATHREKEADLTMHLVRVANPRAFGCVPTDADGRVLEFLEKTEDPPTDQINAGCYVFQREL 197

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTF 236
           +       P++R            L+ G      +   + W D GT    +  S+ 
Sbjct: 198 IASI----PADRVVSVERETFPQLLQEGRRVYGHVDTSY-WRDMGTPQDFVRGSSD 248


>UniRef50_UPI000038E164 mannose-1-phosphate guanyltransferase n=1 Tax=Ferroplasma
           acidarmanus fer1 RepID=UPI000038E164
          Length = 367

 Score =  204 bits (518), Expect = 4e-51,   Method: Composition-based stats.
 Identities = 68/271 (25%), Positives = 124/271 (45%), Gaps = 16/271 (5%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K +++AGG GTRL PIT  + K ++PI  KP + Y L     AGI++++I T  +     
Sbjct: 11  KAVVMAGGKGTRLRPITYSIPKPVVPIAGKPCMLYLLDSYYNAGIKDVIITTGYKFSSLI 70

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLR 121
             ++ +       + ++ +  P G A +  +   F+  + + +V   +I      S  + 
Sbjct: 71  TSIIEN-RHNDQAILFSVEKEPAGTAGSVKMVSNFI--DDTLIVGSGDILSDFNISDIIN 127

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDSK 179
                    T+   +V DP +FG+VE  +N R +   EKP   Q  S+ A TG+Y  + +
Sbjct: 128 FHKKNKAMVTIVLTEVEDPRQFGIVEM-ENNRIVRFLEKPDRDQTFSHIASTGIYVIEPE 186

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           +++Y   +            +    ++        +G+G  WLDTG  + LI A+   Q 
Sbjct: 187 ILDYITTMPYD-----FAKDLFPELMKRNIDIYGYMGKG-VWLDTGRPNDLITAN---QI 237

Query: 240 VEKRQGFKIACLEEIAWRNGWLDDEGVKRAA 270
           + ++ G K + ++ I  +N  LD  G+    
Sbjct: 238 MVEKYG-KPSNVDFIKGKNIILDMAGIHNTG 267


>UniRef50_C7LY80 Nucleotidyl transferase n=1 Tax=Acidimicrobium ferrooxidans DSM
           10331 RepID=C7LY80_ACIFD
          Length = 346

 Score =  204 bits (518), Expect = 4e-51,   Method: Composition-based stats.
 Identities = 67/249 (26%), Positives = 106/249 (42%), Gaps = 9/249 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ IIL GG GTRL P+T    KQ+L +   PM+   +  L   G+ E+++    +   +
Sbjct: 1   MQAIILVGGEGTRLRPLTLHQPKQMLRLLGFPMLERVVERLAAIGVDEVVLSLGYQPDAF 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
             R   D     +++ YA +P P   A A        N   + LV+  ++      +  +
Sbjct: 61  IARY-PDHRIGTVKVRYAVEPEPLDTAGAIRFAVDKGNVHGTFLVVNGDVLTDLDVAQLV 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDS 178
                R   AT+   +V DP RFGVV  DD  RA+   EKP   Q  S+    G+Y  + 
Sbjct: 120 DFHLDRGALATIGLVEVDDPSRFGVVVTDDRGRAVRFVEKPPRDQAPSHAINAGVYVMEP 179

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
             +E        ER  +E +   Q+  E        L +   W+D GT  S + A+  + 
Sbjct: 180 AAIERIAV---GERVSVERSLFPQLASEGTLWG---LAQRCYWVDAGTPASYLRAALDIA 233

Query: 239 TVEKRQGFK 247
           T  +    +
Sbjct: 234 TGRRAARVR 242


>UniRef50_O27787 Mannose-1-phosphate guanyltransferase n=1 Tax=Methanothermobacter
           thermautotrophicus str. Delta H RepID=O27787_METTH
          Length = 385

 Score =  203 bits (517), Expect = 5e-51,   Method: Composition-based stats.
 Identities = 57/268 (21%), Positives = 111/268 (41%), Gaps = 14/268 (5%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQR 63
           +++AGG GTR+ P+T    K L+P+ ++P++ Y +  ++ +G  ++++            
Sbjct: 7   VVMAGGKGTRIRPLTFSRPKPLVPVANRPILDYIIHRVLDSGYSKVVMTLGYLKDQIRSH 66

Query: 64  LLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHV 123
           +L +  E  I   ++ +  P G A       + +N   + +VL  ++ F       ++  
Sbjct: 67  VLAEYPE--IDFRFSVEKKPLGTAGGVKAAASEIN--ETFIVLSGDVIFDLDLREMVKFH 122

Query: 124 AARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEK--PKQPKSNWAVTGLYFYDSKVV 181
             +    TV    V DP  +G+   DD+ +     EK  P++  S  A  G+Y  + +V+
Sbjct: 123 RKKNALVTVALTPVEDPSHYGIAVLDDDGKIKRFHEKPRPEEVFSKIANAGIYVMEPEVI 182

Query: 182 EYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVE 241
           E+  Q             I  + +E        L  G+ W D G  ++ + A+  V    
Sbjct: 183 EHIPQ-----GSSDFSADIFPVLIERDAGMYGFLFDGY-WNDAGKPNTFLRANHDVLNGT 236

Query: 242 KRQGFKIACLEEIAWRNG--WLDDEGVK 267
                     EE+  R G  W+  + V 
Sbjct: 237 VTPEPDGEIAEEVPGRFGKIWIGRDVVI 264


>UniRef50_B9LMT7 Nucleotidyl transferase n=2 Tax=Halobacteriaceae RepID=B9LMT7_HALLT
          Length = 391

 Score =  203 bits (517), Expect = 5e-51,   Method: Composition-based stats.
 Identities = 61/264 (23%), Positives = 116/264 (43%), Gaps = 16/264 (6%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            ++LA G G RL P+T    K ++P+ ++P++ + +  +  AGI  I ++     +   +
Sbjct: 8   AVVLAAGEGRRLEPLTNRRPKPMVPVANRPLLEHVVEAVAAAGINRIALVVGYRQE-RIR 66

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
              GDG ++G+ +EY EQ +  G   A +  E  ++G    +VL  +         ++R 
Sbjct: 67  NHFGDGDDWGVTIEYVEQSTQLGTGHAVLQAEPVVDG--PFVVLNGDRIVDAAVVSRVRD 124

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQP-KSNWAVTGLYFYDSKVV 181
           +A   +   +       P  +GVV  D + R   ++EKP+ P ++N    G+Y +   V 
Sbjct: 125 LARDGDHPAMAVTTAERPREYGVVTLDGD-RVTGIDEKPEGPVETNRINAGVYAFSPAVF 183

Query: 182 EYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS------- 234
           +  ++      GEL IT+       AG+LT   +G    WLD      L+  +       
Sbjct: 184 DAIRET--HTTGELAITATLNELASAGDLTA--VGYDGRWLDVSNLWDLLGVNAALIGES 239

Query: 235 TFVQTVEKRQGFKIACLEEIAWRN 258
              +  +   G  +   +++A   
Sbjct: 240 EQTEPTDAAFGASVTVADDVALAG 263


>UniRef50_Q1ASA7 Nucleotidyl transferase n=1 Tax=Rubrobacter xylanophilus DSM 9941
           RepID=Q1ASA7_RUBXD
          Length = 346

 Score =  203 bits (517), Expect = 6e-51,   Method: Composition-based stats.
 Identities = 59/277 (21%), Positives = 108/277 (38%), Gaps = 13/277 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK + LA G GTRL P+T  V K + P+ + P+I +  ++L   G+R++ +         
Sbjct: 1   MKAMALAAGKGTRLFPLTGEVPKPMAPVVNTPIIEHIFALLASHGMRKVYVNVHYLADAL 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                      G+++  + +    G A            + + +V+  +          +
Sbjct: 61  LNAYGQTSRINGMEVHLSREERLMGTAGGVKRLAD--RFDETFVVVSGDALTDIDLGELV 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEK--PKQPKSNWAVTGLYFYDS 178
                +   AT+   +V D   FGVV+ D        +EK  P++  S  A TG+Y  + 
Sbjct: 119 AFHREKGALATIALKRVYDTSEFGVVDIDAGGNIRGFQEKPPPEEAISTLANTGIYVLEP 178

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           + +EY     P +        +    LEAG   V   G  F W D GT  +  +A   V 
Sbjct: 179 RALEYI----PEDTFFDFAKDVFPQLLEAGEKFVGYQG-DFYWSDIGTLSAYRQAHYDVL 233

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAK 275
           + +     ++    E   +  W+ ++     ++S   
Sbjct: 234 SGK----VRVRIPGEKRSKGLWIGEDAKIHPSASFEG 266


>UniRef50_UPI000186E54F Mannose-1-phosphate guanyltransferase, putative n=1 Tax=Pediculus
           humanus corporis RepID=UPI000186E54F
          Length = 348

 Score =  203 bits (516), Expect = 6e-51,   Method: Composition-based stats.
 Identities = 51/199 (25%), Positives = 86/199 (43%), Gaps = 1/199 (0%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +IL GG GTRL P+T    K L+   +KPM+ + +  L+ AG+ EI++  +   +  
Sbjct: 12  MKALILVGGYGTRLRPLTLSRPKPLVEFANKPMLIHQIEALVDAGVTEIVLAVSYRAQQM 71

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLN-GEPSCLVLGDNIFFGQGFSPK 119
            + L    +  G+ L ++E+  P G A    +    L        VL  +I     F   
Sbjct: 72  EKELTERAANLGVTLIFSEESEPLGTAGPLALAREILGTSSEPFFVLNSDIICDFPFKEM 131

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSK 179
                   +  T+   +V +P ++GVV + +  +  S  EKP++  SN    G+Y     
Sbjct: 132 YEFHKNHGKEGTIVVTKVDEPSKYGVVVYGEEGKVESFIEKPQEFVSNKINAGMYILSPS 191

Query: 180 VVEYAKQVKPSERGELEIT 198
           V++       S   E    
Sbjct: 192 VLKRIALKPTSIENEFFPK 210


>UniRef50_UPI000197A125 nucleotidyl transferase n=1 Tax=Helicobacter cinaedi CCUG 18818
           RepID=UPI000197A125
          Length = 348

 Score =  202 bits (515), Expect = 9e-51,   Method: Composition-based stats.
 Identities = 53/236 (22%), Positives = 99/236 (41%), Gaps = 11/236 (4%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQR 63
           +I+AGG G RL P+T  + K +L +  KP++   L      G   I++    +     + 
Sbjct: 124 VIMAGGLGKRLRPLTDSIPKPMLKVGSKPILQIILERFKAQGFSNIILCVNYK-SHIIED 182

Query: 64  LLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHV 123
             GDGS+FG+ + Y ++    G A A  + +    GE    V+  +I     F   L   
Sbjct: 183 FFGDGSKFGLSIRYVKEEKALGTAGALSLIDNI--GEKPFFVMNGDILSDISFQAMLEFH 240

Query: 124 AARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEY 183
             R   AT+   +      +GVVE +++ + +++ EKP Q  S     G+Y  + +++  
Sbjct: 241 NERGSHATMGVREYSYQVPYGVVECEES-KILNIIEKPTQ--SFLVSAGIYVLEPQILPL 297

Query: 184 AKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
             +         ++ S+  +     +           W+D G H+    A++   T
Sbjct: 298 IPKD-----CFFDMPSLFNLIFSQAHYNSHSYLITDYWIDIGRHEEYERANSEYTT 348


>UniRef50_A6UP85 Glucosamine-1-phosphate N-acetyltransferase n=6 Tax=Methanococcales
           RepID=GLMU_METVS
          Length = 414

 Score =  202 bits (515), Expect = 9e-51,   Method: Composition-based stats.
 Identities = 64/243 (26%), Positives = 114/243 (46%), Gaps = 22/243 (9%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M  +IL  GSGTRL+PIT    K ++PI  KP++ + +  +    + +I ++   E +  
Sbjct: 1   MDAVILCAGSGTRLYPITENRPKPMIPIAGKPILEHIIEKIENH-VEKIYLVVGFEKEKI 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                G+      ++E+  Q    G   A ++ + ++ G+   LVL  ++ F       L
Sbjct: 60  IDYFYGNE-----KIEFIVQEKQLGTGHAVLMAKNYIKGD--FLVLNGDVIFESDILEFL 112

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPK------SNWAVTGLY 174
            +  A      V   +V +PE FGV+E   + + I+L EKP + +      SN    G+Y
Sbjct: 113 NYENA------VGLSKVDNPENFGVIELGYDNKVINLLEKPNEDEIKSKFTSNLINAGIY 166

Query: 175 FYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
             ++ V E  + + PSERGE+E+T   +  +E+  L    +     W D G    ++ A+
Sbjct: 167 KLENFVFEILENLLPSERGEIELTDALKKLIESSKL--YGIELNGYWNDIGRPWDVLSAN 224

Query: 235 TFV 237
            + 
Sbjct: 225 NYF 227


>UniRef50_C6PCK2 Nucleotidyl transferase n=1 Tax=Thermoanaerobacterium
           thermosaccharolyticum DSM 571 RepID=C6PCK2_CLOTS
          Length = 781

 Score =  202 bits (515), Expect = 9e-51,   Method: Composition-based stats.
 Identities = 59/278 (21%), Positives = 113/278 (40%), Gaps = 16/278 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK II+AGG G+RL P+T G+ K ++PI  KP I++ ++ +   GI ++  +T       
Sbjct: 1   MKAIIMAGGEGSRLRPLTCGIPKPMVPIAGKPAIWHIINHIGRYGINDLG-VTLFYLPDK 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  L    ++G +++Y  +  P G A +      FL  + + +V+  ++          
Sbjct: 60  IKNYL--YEQYGDKIKYYVEDKPLGTAGSVKNAVDFL--DETFVVMSGDVITDIDLRKAH 115

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
                     T+   +V  P  +GVV  D+N R     EKP   +  S+   TG+Y  + 
Sbjct: 116 DFHKNSGSKVTLVLTRVDIPLEYGVVITDENGRIFKFLEKPSWGEVFSDTVNTGIYIIEP 175

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           ++++      P ++       +  M LE        +   + W D G+    +++   + 
Sbjct: 176 EILDLI----PEDKQFDFSKDLFPMLLEKKIPMYGFVSDNY-WCDIGSGVQYLKSHLDLL 230

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKT 276
                 GFK    E++           +    + L   
Sbjct: 231 RGYVDLGFK----EKVNKDGIIYGKNVIVSENAKLVPP 264


>UniRef50_A4I048 Mannose-1-phosphate guanyltransferase n=5 Tax=Leishmania
           RepID=A4I048_LEIIN
          Length = 379

 Score =  202 bits (515), Expect = 1e-50,   Method: Composition-based stats.
 Identities = 52/232 (22%), Positives = 94/232 (40%), Gaps = 9/232 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +IL GG GTRL P+T    K L+P  +KPMI + +  L   G+ E+++      +  
Sbjct: 9   MRAVILVGGFGTRLRPLTLTTPKPLVPFCNKPMIIHQIEALKAVGVTEVILAVAYRPEAM 68

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFL-NGEPSCLVLGDNIFFGQGFSPK 119
            +++     + G+   ++ +  P G A    +    L   +    VL  ++         
Sbjct: 69  KEQMDEWSRKLGVSFVFSVEEEPLGTAGPLALARDILMQDDKPFFVLNSDVTCTFPMQEL 128

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFD-DNFRAISLEEKPKQPKSNWAVTGLYFYDS 178
           L    A     T+   QV   E++GVV +   N++     EKP +   +    G+Y ++ 
Sbjct: 129 LDFHKAHGGEGTIMVSQVTQWEKYGVVVYSPQNYQIERFVEKPSRFLGDRINAGIYIFNK 188

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSL 230
            +++     + S   E+      +  L A NL          W+D G     
Sbjct: 189 SILDRIPPRRTSIEKEIFPAMAAEGQLYAFNL-------EGFWMDVGQPKDY 233


>UniRef50_B8D5T2 Putative sugar-phosphate nucleotidyl transferase n=2
           Tax=Thermoprotei RepID=B8D5T2_DESK1
          Length = 283

 Score =  202 bits (514), Expect = 1e-50,   Method: Composition-based stats.
 Identities = 64/240 (26%), Positives = 103/240 (42%), Gaps = 11/240 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M  +ILAGG G RL P T  V K ++P+ DKP++ + +  L   G REI+++     +  
Sbjct: 43  MLAVILAGGYGKRLRPYTDDVPKPMIPVGDKPILEWQIEWLKKYGFREIVLLVGYRKEKI 102

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  +G GS  G+++ Y  +  P G   A    E  L+   + LV+  +I         +
Sbjct: 103 IE-YIGSGSRLGVRVTYVVEDEPLGTGGAIKNAEHVLSRNGTFLVINGDIITNLNPLKLV 161

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
             +        +    +  P  +GV+E +D  R     EKP Q    W   G+Y  + + 
Sbjct: 162 EKLEGSRYLGVIASIPL--PSPYGVLEIEDEDRVKGFVEKP-QLSDYWINAGVYALNPEA 218

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           + Y       E+G+LE T+   M  +    TV     G  W    T   L EAS  +  +
Sbjct: 219 LRYFP-----EKGDLEKTAFPAMARDGVLGTVRY--TGVFWKAIDTFKELEEASRAIHEI 271


>UniRef50_A8GZ91 Nucleotidyl transferase n=5 Tax=Gammaproteobacteria
           RepID=A8GZ91_SHEPA
          Length = 397

 Score =  202 bits (514), Expect = 1e-50,   Method: Composition-based stats.
 Identities = 60/253 (23%), Positives = 109/253 (43%), Gaps = 20/253 (7%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+ILA G GTR+ PI+  + K ++PI  KP++   + +    GI +I+I T+      
Sbjct: 1   MKGMILAAGKGTRIKPISYAIPKPMVPILGKPVMESMIQLFAKHGIDKIVINTSH-LAEI 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPS---------PDGLAQAFIIGETFLN-GEPSCLVLGDNI 110
            +   GDG  F +QL Y+ +             G A      + F    + + +V+  + 
Sbjct: 60  IESYFGDGHHFNVQLSYSYEAKEVNGEYISQALGSAGGMRKIQDFSGFFDETFVVVCGDA 119

Query: 111 FFGQGFSPKLRHVAARTEGATVFGYQVM--DPERFGVVEFDDNFRAISLEEKPK--QPKS 166
           +        + H  +    AT+   +V   +  ++GVV  D + +  S +EKP   +  S
Sbjct: 120 WIDLDLKQAIEHHKSHGGLATIITREVASSEVSKYGVVVTDKHNQVTSFQEKPAEDEALS 179

Query: 167 NWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGT 226
           N   TG+Y ++  + ++  +       E +I S     L      +  +   F WLD G 
Sbjct: 180 NRINTGIYIFEPAIFDFIPKDV-----EFDIGSDLFPLLVERQANLYAINMDFQWLDVGK 234

Query: 227 HDSLIEASTFVQT 239
              + E ++ +  
Sbjct: 235 VKDVWEVTSDILN 247


>UniRef50_Q6L165 Mannose-1-phosphate guanyltransferase n=3 Tax=Thermoplasmatales
           RepID=Q6L165_PICTO
          Length = 361

 Score =  202 bits (514), Expect = 1e-50,   Method: Composition-based stats.
 Identities = 63/268 (23%), Positives = 118/268 (44%), Gaps = 16/268 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +K +++AGG GTRL PIT  + K L+PI  KP + Y +     AGI++ ++ T  + +  
Sbjct: 3   LKAVVMAGGKGTRLRPITYSIPKPLVPIAGKPCVSYLMDSFYDAGIKDAIVTTGYKFESL 62

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
               + +  +    + ++ +  P G A +  +   F+  + + +V   +I +       +
Sbjct: 63  I-NGIIEAKKPDQNVLFSVEREPAGTAGSVKLISNFI--DDTIVVGSGDILYDFDIKSII 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
                +    T+   +V DP +FG+V+  D+       EKP   +  SN    G+Y  + 
Sbjct: 120 DFHKKKNASVTIVLTRVDDPSQFGIVDLKDDV-ITRFLEKPAAGEAFSNIVNAGIYVIEP 178

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +V++Y  ++      E     +    +  G      LG G  WLDTG  + LI+ +   Q
Sbjct: 179 EVLKYIDKIPFDFAKE-----LFPRLMRHGTPIYGYLGNG-TWLDTGRPNDLIKGN---Q 229

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGV 266
            +  + GFK    + I  +N       +
Sbjct: 230 IMVNKYGFKYDS-KNITGKNIIKTTSDL 256


>UniRef50_Q23RS7 Nucleotidyl transferase family protein n=3 Tax=Eukaryota
           RepID=Q23RS7_TETTH
          Length = 706

 Score =  202 bits (513), Expect = 2e-50,   Method: Composition-based stats.
 Identities = 54/272 (19%), Positives = 110/272 (40%), Gaps = 27/272 (9%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +IL GG GTRL P+T    K ++   ++P++ + +  L+  G+ +I++    + K  
Sbjct: 1   MKALILVGGFGTRLRPLTFSCPKSIVEFANQPLVTHQIKALVDVGVTDIILAIGFQPKAM 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFL---NGEPSCLVLGDNIFFGQGFS 117
            +++     E+ +++  +++  P G      + +  L   N E    VL  ++     F 
Sbjct: 61  IEKIKQFEEEYKVRIICSQEVEPLGTGGPLRLAKEHLVKDNPEGLFFVLNSDVICDFPFK 120

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYD 177
             L       +  T+   +V DP ++GVV  D N R     EKPKQ  S+    G+Y ++
Sbjct: 121 EMLAFHKNHQKEGTILLTKVQDPTKYGVVVSDSNGRIERFIEKPKQFISDRINAGIYLFN 180

Query: 178 SKVVEYAK------------------------QVKPSERGELEITSINQMYLEAGNLTVE 213
           + V++                           +   +++ E  +  +N     A    + 
Sbjct: 181 TSVIDRIPVILFLFLPNFLHLAIIHLLIFIFKKYFVNQQLEPHMLELNTFPTMAKEAQLY 240

Query: 214 LLGRGFAWLDTGTHDSLIEASTFVQTVEKRQG 245
            +     W+D G     +  +T +    + + 
Sbjct: 241 SMDLPGFWMDVGQPKDFVIGTTLILESIRTKN 272


>UniRef50_Q12TW4 Mannose-1-phosphate guanyltransferase n=11 Tax=Euryarchaeota
           RepID=Q12TW4_METBU
          Length = 399

 Score =  202 bits (513), Expect = 2e-50,   Method: Composition-based stats.
 Identities = 65/250 (26%), Positives = 100/250 (40%), Gaps = 9/250 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK  I+ GG GTRL P+T    K  +PI +KP + + +  L   G  EI +IT       
Sbjct: 14  MKACIMCGGEGTRLRPLTFERPKPSIPILNKPSVVHLVEHLAKEGFTEI-VITIGYMAEK 72

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  LGDG  +G+ +EY  +    G A      E FL  EP  +V G +           
Sbjct: 73  IEECLGDGRMYGVYIEYVYEEKRLGTAGGVKNAEEFLKDEPFMIV-GGDHVMDLSLRSIY 131

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEK--PKQPKSNWAVTGLYFYDS 178
           R         T+    + DP  FG+ + D N R     EK  P +  SN A TG+Y    
Sbjct: 132 RQHEMNDAMITIGLMSIDDPREFGIADMDVNNRIHRFLEKPGPGEIFSNLASTGIYMCSP 191

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           ++ ++     P +        +    +  G     +L RG  W D G+  +  +A  ++ 
Sbjct: 192 EIFDWI----PKDEKYDFAKDLFPALMSKGKKINGMLVRG-HWTDVGSSTAYRQAQRWML 246

Query: 239 TVEKRQGFKI 248
                   + 
Sbjct: 247 ESLPGTSIEG 256


>UniRef50_B0R8I5 Sugar nucleotidyltransferase n=2 Tax=Halobacterium salinarum
           RepID=B0R8I5_HALS3
          Length = 395

 Score =  201 bits (512), Expect = 2e-50,   Method: Composition-based stats.
 Identities = 66/288 (22%), Positives = 118/288 (40%), Gaps = 19/288 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ ++LA G G RL P+T    K ++P+ ++P++ + +  L+ AG+  ++++    ++  
Sbjct: 1   MQAVVLAAGKGERLWPLTENRPKPMVPVANQPILEHIVDALVSAGVTRVMLVVG-SNRER 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            QR   DGS +GI++ Y  Q    G   A    E+ + GE    + GD +          
Sbjct: 60  VQRHFEDGSRWGIEISYVVQDRQLGTGHALAQAESVV-GESFVALNGDRVIDASLVEDVW 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEE--KPKQPKSNWAVTGLYFYDS 178
                  + A +   QV  P  +GVV+ D       ++E   P+   S +   G+Y +  
Sbjct: 119 ECHRESGDSA-MGVTQVETPSAYGVVDLDG-GTVTDIDEQPVPELVASEYINAGVYAFGP 176

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS---- 234
            V    ++      GEL +T      L    L    +     WLD      L+ A+    
Sbjct: 177 SVFAAIRRTD--SYGELALTDALDEQLADHEL--RAVRYDGRWLDVSEPWDLVAANSALI 232

Query: 235 ---TFVQTVEKRQ--GFKIACLEEIAWRNGWLDDEGVKRAASSLAKTG 277
               F   VE+R+  G      ++     G +  EGV     ++ + G
Sbjct: 233 TDRRFDPPVERRKPRGSVPGDDQQAPVGGGTVCGEGVIVHPQAVVRNG 280


>UniRef50_A9A224 Nucleotidyl transferase n=3 Tax=Thaumarchaeota RepID=A9A224_NITMS
          Length = 238

 Score =  201 bits (511), Expect = 3e-50,   Method: Composition-based stats.
 Identities = 52/238 (21%), Positives = 103/238 (43%), Gaps = 11/238 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +K +ILAGG GTRL P+T    K +LP+  KP++ + +      G++ I++  +   K  
Sbjct: 4   VKAVILAGGLGTRLRPLTLKTPKPMLPLGKKPILEHLIDWNKRNGVKSIVLCVSYR-KEK 62

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            Q    DG +FG+ +EYA    P   A      E F+N   + + +  +  F       +
Sbjct: 63  IQDYFKDGKKFGVNIEYAVSKKPLATAGQLKTAEDFIND--TFVCVYGDSIFDFSLKNMI 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           +   ++    T+  Y+     ++GV+      +  + EEKP+         G Y  +  V
Sbjct: 121 KQHKSKKAFTTMSLYEYKTNLQYGVINTTKTGKVTNWEEKPE--IKANINMGCYVMEPNV 178

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           ++Y  + KP       +  + +  ++   +    + +   ++D G  +S  +A+    
Sbjct: 179 LKYIPKNKPYG-----MDDVIKKAMKNKKMISGFITKKG-FMDIGNKESYKQANEEFA 230


>UniRef50_Q2WB86 Nucleoside-diphosphate-sugar pyrophosphorylase n=7 Tax=Bacteria
           RepID=Q2WB86_MAGSA
          Length = 349

 Score =  200 bits (510), Expect = 4e-50,   Method: Composition-based stats.
 Identities = 60/237 (25%), Positives = 95/237 (40%), Gaps = 12/237 (5%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQR 63
           +++AGG G RL P+T+ V K LLP+  +P++   L   + AG R   I      +   + 
Sbjct: 123 VLMAGGEGRRLRPLTQDVPKPLLPVGPRPILETILKNFIEAGFRNFFISVNYRAEQ-VES 181

Query: 64  LLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHV 123
             GDGS  G+ + Y  +    G A A  +           +V+  +I     F   L   
Sbjct: 182 HFGDGSALGVSIRYLREDRQLGTAGALGLLPG--TPSEPLIVMNGDILTTVDFKQLLAFH 239

Query: 124 AARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEY 183
                 AT+   +      +GVVE  +  R   +EEKP     N+   G+Y  + +V+  
Sbjct: 240 QEHRAAATMAVREYHFEVPYGVVEV-EGTRLKGIEEKP--VVRNFVNAGIYVLNPEVLNL 296

Query: 184 AKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            K  +P       +  I Q  ++ G        R + WLD G  D    A+     V
Sbjct: 297 VKPGQP-----HNMPQIYQTLMDGGQDCAVFPIREY-WLDIGRLDDFDRANLDFHEV 347


>UniRef50_Q2FRV9 Nucleotidyl transferase n=7 Tax=cellular organisms
           RepID=Q2FRV9_METHJ
          Length = 401

 Score =  200 bits (508), Expect = 6e-50,   Method: Composition-based stats.
 Identities = 62/235 (26%), Positives = 105/235 (44%), Gaps = 11/235 (4%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +ILA G G R+ P+T    K +LP+  +PM+ + L+ +M AGI + + +    +    +
Sbjct: 4   CVILAAGEGKRMRPLTGSRPKVMLPLAGRPMLEHLLNAVMDAGITDFIFVVGYGEAS-VR 62

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
              GDG+  GI + Y  Q    G   A +     ++ +   L+ GD +         L  
Sbjct: 63  NFFGDGTSKGISIRYVTQKRQQGTGDALMTVRPHVHSQ-FLLLNGDMVLHSDDIKAML-- 119

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
              +T    +  +    P+ +GVV  D +     LEEK   PKS+    G+Y ++  + E
Sbjct: 120 ---KTPAPAMGVFTSNHPQDYGVVTMDGDI-ITGLEEKSLHPKSDLINAGMYLFEPGIFE 175

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
             + ++PS RGELE+T     Y++   L    L     W D G+   L+     +
Sbjct: 176 ELETIRPSPRGELELTDALMTYIQNKTLRGVRLSF---WADMGSPWDLLGVHEEM 227


>UniRef50_C8SCM3 Nucleotidyl transferase n=1 Tax=Ferroglobus placidus DSM 10642
           RepID=C8SCM3_FERPL
          Length = 390

 Score =  199 bits (506), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 63/243 (25%), Positives = 118/243 (48%), Gaps = 16/243 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +ILA G G RL P T    K ++ + +KP++ Y +  L  AGIREI+++   + +  
Sbjct: 1   MKAVILAAGEGQRLRPFTANKPKVMIKVGNKPILEYVVDALKEAGIREIVMVVGYKKERV 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                G+G +FG+++EY  Q    G A A    +  + G+   ++ GDNI   +     L
Sbjct: 61  I-DYFGNGEKFGVKIEYVTQKQQLGTAHALKQAKDLVEGK-FLVLPGDNIIDSETLKDVL 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
            +     +  +V    V +P ++GV+E  +N +   + EKP++  S  A TG+Y  D ++
Sbjct: 119 SY-----DTFSVVYKVVEEPTKYGVLEV-ENGKVKRIIEKPEEEVSYLASTGIYLLDDRI 172

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            E+          E ++T++  + +E+G     +  +G  WLD      +++ +      
Sbjct: 173 FEFIGD-------ERDLTNVVNVMIESGIDFFTVESKGL-WLDIVYPWDILKVNDLALKH 224

Query: 241 EKR 243
           + +
Sbjct: 225 KGK 227


>UniRef50_A0B7L5 Nucleotidyl transferase n=1 Tax=Methanosaeta thermophila PT
           RepID=A0B7L5_METTP
          Length = 403

 Score =  199 bits (506), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 60/239 (25%), Positives = 102/239 (42%), Gaps = 10/239 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ IILA G G+R+ P+T    K +LP+   P++   +     AGI   + +     +  
Sbjct: 4   MQAIILAAGEGSRMRPLTASRPKVMLPVGGAPLLEELVLRCREAGINRFVFVVGYR-RDV 62

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                 DGS+F + + YA Q    G   A +     L+ +   ++ GD +   Q     +
Sbjct: 63  VTSYFKDGSDFDVDISYAVQEKQLGTGHALMTARD-LSDDRFFVINGDVLPDVQALRRMI 121

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                  E  +V  ++V++  R+GV    D      + EK   P S+ A  G+Y  D ++
Sbjct: 122 -----SMEDLSVATHRVVEASRYGVFLLRDGL-VEGVVEKSPSPPSDMANAGIYLLDREI 175

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
            E  ++V  S RGE E+T        AG     +      W++ G    ++ AS  V +
Sbjct: 176 FELMEEVPVSIRGEYELTDGINALASAGRKIWAIELSE--WVEVGVPWDILTASNAVLS 232


>UniRef50_Q67QD8 Putative mannose-1-phosphate guanyltransferase n=1
           Tax=Symbiobacterium thermophilum RepID=Q67QD8_SYMTH
          Length = 343

 Score =  198 bits (503), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 63/244 (25%), Positives = 100/244 (40%), Gaps = 16/244 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDK-- 58
           ++ I+LAGG GTRLHP+T  + K ++P+  KP +   +  L   G+ +I +      +  
Sbjct: 3   VRAILLAGGLGTRLHPLTVELPKPMVPVLGKPWLSRLIDQLAAFGVTDITLSLRHGGQVV 62

Query: 59  -GYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
             YF+      S  G++L +A +P P G   A        +   + L+L  +I      +
Sbjct: 63  TDYFRE-----SPPGVRLRFAVEPQPLGTGGAIRFAAGP-DPTDTLLILNADIVQTFDLN 116

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYF 175
             L          T+   +V DP  +G VE D N R     EKP+  +  S     G+Y 
Sbjct: 117 ALLEFHRQHRAQVTIGLVEVADPSAYGAVELDKNSRVTRFVEKPRPGETDSRMVNAGVYV 176

Query: 176 YDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAST 235
           +D  V+ +     P ER            L  G      L  G+ W D GT D  ++   
Sbjct: 177 FDPGVLSWI----PPERPVSVERETFPALLRDGVRVYGCLCTGY-WKDIGTGDRYLQLHR 231

Query: 236 FVQT 239
            +  
Sbjct: 232 DILE 235


>UniRef50_C7LVF0 Nucleotidyl transferase n=2 Tax=Proteobacteria RepID=C7LVF0_DESBD
          Length = 355

 Score =  197 bits (501), Expect = 4e-49,   Method: Composition-based stats.
 Identities = 48/236 (20%), Positives = 89/236 (37%), Gaps = 12/236 (5%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQR 63
           +I+AGG GTRL P T    K +LP+  KPM+ + +      G R  ++          + 
Sbjct: 128 VIMAGGMGTRLLPYTEDCPKPMLPVAGKPMLEHIIERAKNEGFRHFVLAVRY-LAHVVED 186

Query: 64  LLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHV 123
             GDG+++ +++ Y  + +P G A A  + +         +V   ++     +   +   
Sbjct: 187 YFGDGAKWDVRISYLHEDTPLGTAGALGLLDP--KPMEPVVVTNGDVLTDVRYGEIVDFH 244

Query: 124 AARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEY 183
                 AT+          FGVV+ +     +  EEKP          G+Y   ++ +  
Sbjct: 245 IYHQAAATMAVRMHEWQHPFGVVQTNG-VSIVGFEEKP--VFRTHVNAGIYVLGAEALRL 301

Query: 184 AKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
               KPS+     +  I ++        +        W D G  D L +    ++ 
Sbjct: 302 VPSGKPSD-----MPDIFELLRLRDERIIAYPMHEI-WTDVGRPDDLKKVRNEMRP 351


>UniRef50_Q28JE9 Nucleotidyl transferase n=1 Tax=Jannaschia sp. CCS1
           RepID=Q28JE9_JANSC
          Length = 240

 Score =  197 bits (501), Expect = 4e-49,   Method: Composition-based stats.
 Identities = 58/240 (24%), Positives = 95/240 (39%), Gaps = 8/240 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +K ++LAGG GTRL P+T  + K L+P+  KP++ Y L  L  A IR+ L+ T  +    
Sbjct: 4   VKALLLAGGLGTRLRPLTDTLPKCLIPVAGKPILDYWLDALDAADIRQALLNTHHKRDQV 63

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
              L    S   + +  A +P   G A        + +     +V+  +          +
Sbjct: 64  KIWLETANSSRNVAIAEAYEPELLGSAGTVTANRDWADDASEVVVIYADNLSDIDLGALV 123

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                 ++  T+  +    P + G+   DD+ R  +  EKP QP+S+ A  GLY  D+  
Sbjct: 124 AFHRTHSDPMTMMLFHTPYPSKCGIATLDDDARVTAFVEKPDQPESDLANAGLYVLDASA 183

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
                 +   + G   I +                       D GTH+SL +A      V
Sbjct: 184 WREIADMGAFDFGFDVIPAFVGRM--------RGYAHPGYHRDIGTHESLAQAEADAPVV 235


>UniRef50_B1XM99 Sugar-phosphate nucleotidyl transferase n=59 Tax=cellular organisms
           RepID=B1XM99_SYNP2
          Length = 409

 Score =  197 bits (500), Expect = 5e-49,   Method: Composition-based stats.
 Identities = 64/247 (25%), Positives = 103/247 (41%), Gaps = 20/247 (8%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +ILA G GTR+ PIT  + K L+PI  KP++ + L +L   G  +I++  +      
Sbjct: 1   MKAMILAAGKGTRVRPITYTIPKPLIPILQKPVMEFLLDLLAQHGFDQIMVNVSH-LAHE 59

Query: 61  FQRLLGDGSEFGIQLEYAE---------QPSPDGLAQAFIIGETFLN-GEPSCLVLGDNI 110
            +    DG  +G+ L Y+          Q +  G A      + F    + + +VL  + 
Sbjct: 60  IEGYFKDGQRYGVHLAYSFEGSIQDGELQGAALGSAGGLRKIQDFHPFFDDTFVVLCGDA 119

Query: 111 FFGQGFSPKLRHVAARTEGATVFGYQVMD--PERFGVVEFDDNFRAISLEEKPK--QPKS 166
                 +  +R    +   ATV    V       +GVV  DD  R +S +EKP   +  S
Sbjct: 120 LIDLDLTAAVRWHREKGAIATVITKSVPKEAVSSYGVVVTDDEDRILSFQEKPSVTEALS 179

Query: 167 NWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGT 226
               TG+Y ++ +V+++          E +I       L A N     L   F W+D G 
Sbjct: 180 TKINTGIYIFEPEVIDFIP-----PNCEFDIGGQLFPKLVAANAPFYALDMDFEWVDIGK 234

Query: 227 HDSLIEA 233
                +A
Sbjct: 235 VPDYWQA 241


>UniRef50_A8G626 Nucleoside-diphosphate-sugar pyrophosphorylase n=1
           Tax=Prochlorococcus marinus str. MIT 9215
           RepID=A8G626_PROM2
          Length = 352

 Score =  197 bits (500), Expect = 5e-49,   Method: Composition-based stats.
 Identities = 63/234 (26%), Positives = 97/234 (41%), Gaps = 12/234 (5%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQR 63
           II+AGG G+RL P T    K +L I  KP++   +   + +G RE  I      K   + 
Sbjct: 128 IIMAGGLGSRLRPHTDKCPKPMLKINGKPILEIIIKNCIDSGFREFFISVNY-LKNIIKD 186

Query: 64  LLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHV 123
             GDGS++GI++ Y E+  P G   + I+    L      LVL  ++      S  L   
Sbjct: 187 YFGDGSKWGIKISYLEENEPLGTGGSLILLPKDLKN--PFLVLNGDVLTKFNPSKLLEFH 244

Query: 124 AARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEY 183
                 AT+   + +    FGVVE D   +   L EKP  PK      G+Y  +  V+  
Sbjct: 245 NKNNATATLSVREYILEVPFGVVETDG-LQVTDLLEKPSYPK--LVNAGVYVLNPNVISL 301

Query: 184 AKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
            K  +  +  E     +     +     +      + WLD G  +SL +A +  
Sbjct: 302 IKNEEKLDMPE-----LLLRVQQRSQKVIAFPIHEY-WLDIGRLESLKKAFSTW 349


>UniRef50_A3CRY9 UDP-glucose pyrophosphorylase n=2 Tax=Methanomicrobia
           RepID=A3CRY9_METMJ
          Length = 262

 Score =  196 bits (498), Expect = 8e-49,   Method: Composition-based stats.
 Identities = 74/241 (30%), Positives = 120/241 (49%), Gaps = 7/241 (2%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           +G+I A GSG+RL P T  + K+LLP+ +K +I + +  + LAGI +I+I+ +P   G  
Sbjct: 5   QGLIPAAGSGSRLGPFTNAIPKELLPVGEKAVIEHVVEAMSLAGITDIVIVVSPHKHG-L 63

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGF-SPKL 120
              LG G  FG+   Y  Q    GLA A   GE  ++G    +VLGDN F  + F +  +
Sbjct: 64  SDYLGSGKRFGVDFTYVVQDERLGLANAVAAGEHVIDG-TFAVVLGDNFFAPKTFLADLI 122

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
            + AA     TV   +V D  R G++  D + R   + EKP+     SN    G Y +++
Sbjct: 123 GYHAAHRPDTTVGVARVEDVTRHGIILPDGD-RVADMVEKPQPTAAPSNLGALGAYVFET 181

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
            + +   + KP  +GE ++T   ++ +  G      +  G   +D GT   L+ A+ +  
Sbjct: 182 SIFDAIARTKPGHKGEYQLTDAIRLEIAEGRDVRYRVIDGIH-IDVGTPRDLMRANEWYL 240

Query: 239 T 239
            
Sbjct: 241 R 241


>UniRef50_Q8YRP4 Mannose-1-phosphate guanyltransferase n=11 Tax=Bacteria
           RepID=Q8YRP4_ANASP
          Length = 389

 Score =  195 bits (497), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 59/248 (23%), Positives = 103/248 (41%), Gaps = 21/248 (8%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +ILA G GTR+ PIT  + K ++PI  KP++ + L +L   G  +I++  +   +  
Sbjct: 1   MKAMILAAGKGTRVRPITYTIPKPMIPILQKPVMEFLLELLRQHGFDQIMVNVSHLAEE- 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPD----------GLAQAFIIGETFLN-GEPSCLVLGDN 109
            +    DG  FG+Q+ Y+ +   D          G A      + F    + + +VL  +
Sbjct: 60  IENYFRDGQRFGVQIAYSFEGKIDDEGKLVGEAIGSAGGMRRIQDFSPFFDDTFVVLCGD 119

Query: 110 IFFGQGFSPKLRHVAARTEGATVFGYQV--MDPERFGVVEFDDNFRAISLEEKP--KQPK 165
                  +  ++   ++   AT+    V   +   +GVV  D+N R  + +EKP  ++  
Sbjct: 120 ALIDLDLTAAVKWHKSKGSIATIITKTVPEEEVSSYGVVVTDENSRVKAFQEKPSIEEAL 179

Query: 166 SNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTG 225
           S    TG+Y ++ +V  Y          E +I       L         +   F W+D G
Sbjct: 180 STNINTGIYIFEPEVFNYIPS-----GVEYDIGGQLFPKLVEIGAPFYAIAMDFEWVDIG 234

Query: 226 THDSLIEA 233
                  A
Sbjct: 235 KVPDYWRA 242


>UniRef50_C4SU82 Nucleoside-diphosphate-sugar pyrophosphorylase involved in
           lipopolysaccharide biosynthesis/translation initiation
           factor 2B, gamma/epsilon subunits n=4 Tax=Yersinia
           RepID=C4SU82_YERFR
          Length = 387

 Score =  195 bits (496), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 59/267 (22%), Positives = 109/267 (40%), Gaps = 24/267 (8%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +ILA G GTR  P+T  + K ++P+  KP++   +  L   G  ++++ T+      
Sbjct: 1   MKAMILAAGKGTRARPLTTILPKPMIPLIRKPIMESIIEHLRKYGFNQLMVNTSY-LSAD 59

Query: 61  FQRLLGDGSEFGIQLEYAEQ---------PSPDGLAQAFIIGETFLN-GEPSCLVLGDNI 110
            +    DG  +G+++ Y+ +          +  G A      + F    + + +V+  + 
Sbjct: 60  IENYFRDGHAWGVEIGYSYEGVMEGNTFVDNVLGSAGGMKHIQNFSGFFDETFVVVCGDA 119

Query: 111 FFGQGFSPKLRHVAARTEGATVFGYQV--MDPERFGVVEFDDNFRAISLEEKP--KQPKS 166
                F   L    AR   AT+    V      ++G+V  D+  R    +EKP  +   S
Sbjct: 120 LIDVDFDEVLAFHRARKSVATLVIRPVSADQVNKYGIVVTDEQGRVSQFQEKPKTEDALS 179

Query: 167 NWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGT 226
           N A TG+Y ++ ++ +Y       +  E +I S     L    +    +   F W+D G+
Sbjct: 180 NNANTGIYVFEPEIFDYIP-----DGVEYDIGSQLFPKLAELGIPFYGIASPFQWVDIGS 234

Query: 227 HDSLIEASTFVQTVE----KRQGFKIA 249
                  +  +   +       G KIA
Sbjct: 235 LQDFWHVNRMILNQDLPDYPMPGIKIA 261


>UniRef50_Q97EQ2 Nucleoside-diphosphate-sugar pyrophosphorylase n=1 Tax=Clostridium
           acetobutylicum RepID=Q97EQ2_CLOAB
          Length = 234

 Score =  195 bits (496), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 57/232 (24%), Positives = 99/232 (42%), Gaps = 9/232 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +IL GG GTRL  + +   K +  + +KP + Y +  L   GI +I++ T      +
Sbjct: 1   MQALILVGGLGTRLRSVVKDRPKPMALVENKPFLEYLIRKLKSNGISDIILATGY-MSEF 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +    DG EFG+ + Y+++ +  G A A    E +L  E    VL  + +F   F    
Sbjct: 60  IENYFKDGREFGVNIVYSKETTQLGTAGAIKNAEEYLKEE--FFVLNGDTYFDVDFESAY 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           +         T+   +  D  R+G VE  D+ R +S  EK    KSN+   G+Y    ++
Sbjct: 118 KFHKNNKSYFTMILRETSDASRYGAVECSDDNRVVSFIEKGGISKSNYINGGIYIVKKEI 177

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIE 232
            +  ++    E+     T I    L    +          ++D G  +  I+
Sbjct: 178 FKEIER----EKKVSLETEIIPKVLGEEVIYGYKCNN--YFIDIGVPEDYIK 223


>UniRef50_D2EEI5 Nucleotidyl transferase n=1 Tax=Candidatus Parvarchaeum acidiphilum
           ARMAN-4 RepID=D2EEI5_9EURY
          Length = 273

 Score =  195 bits (496), Expect = 2e-48,   Method: Composition-based stats.
 Identities = 54/237 (22%), Positives = 101/237 (42%), Gaps = 13/237 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +ILAGGSGTRL P+T  + K ++ +  +P++ + +  L  A   +I+I          +
Sbjct: 49  ALILAGGSGTRLRPLTYEIPKPMMLVNGRPILEHIIEQLKKAEFVDIIISIGY-LGSRIK 107

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
              GDGS+FG+++ Y+E+ +P G   A    +     +   +VL  +  F    +     
Sbjct: 108 EYFGDGSKFGVRIRYSEETTPVGTGGAIKKNQNLFQED--FIVLNGDNLFDFDLNKIYEF 165

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK-QPKSNWAVTGLYFYDSKVV 181
                  AT+         +FGVVE + N + +   EKPK +  S+    G+Y  +   +
Sbjct: 166 HKKEKAMATIALVLRDGVSQFGVVEMEGN-KIVKFIEKPKIEQVSHLVNAGIYVINPAFL 224

Query: 182 EYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
            +         GE  I+++ +  +E   +   +      WL   + +   +A     
Sbjct: 225 SFIPS------GESNISNVFEKVVEKRIIDGFIY--SGKWLPCDSIELYEKAIKNWP 273


>UniRef50_C0G2T6 Nucleotidyl transferase n=1 Tax=Natrialba magadii ATCC 43099
           RepID=C0G2T6_NATMA
          Length = 417

 Score =  195 bits (495), Expect = 2e-48,   Method: Composition-based stats.
 Identities = 67/280 (23%), Positives = 124/280 (44%), Gaps = 8/280 (2%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            ++LA G G RL P+T    K ++P+ ++P++ Y +S L  AGI  I+++     +   +
Sbjct: 34  AVVLAAGEGRRLDPLTNRRPKPMVPVANRPILDYVVSALAGAGIDRIVLVVGYRQE-RIR 92

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
              GDG ++ + +EY  Q +  G A A +  E  ++G P  ++ GD I      S     
Sbjct: 93  NYFGDGDDWDVDIEYVVQETQLGTAHAVLQAEEVVDG-PFLVLNGDRIVDPALVSQVRDA 151

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP-KQPKSNWAVTGLYFYDSKVV 181
           VA   +   +   +      +GVV  + N R   + EKP    +S     G+Y + + + 
Sbjct: 152 VATDADRPVLSVTRSAHASDYGVVSLEGN-RVTGITEKPIAPARSELINAGVYGFANDIF 210

Query: 182 EYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVE 241
           E  ++  P+E GEL IT+  +  L   + +   +     WLD      L++ +  +   +
Sbjct: 211 EAIRET-PTEEGELAITTTLETIL--ADRSASAVQEHDIWLDVSYLWDLLDVNAAILGDD 267

Query: 242 KRQGFKIACLE-EIAWRNGWLDDEGVKRAASSLAKTGYGQ 280
           + +  + + LE E+A          +   A+    T  G 
Sbjct: 268 EFETTQESTLEGEVATDTAIGTAVSLGANATVGGSTALGD 307


>UniRef50_Q1AVJ3 Nucleotidyl transferase n=1 Tax=Rubrobacter xylanophilus DSM 9941
           RepID=Q1AVJ3_RUBXD
          Length = 367

 Score =  194 bits (494), Expect = 2e-48,   Method: Composition-based stats.
 Identities = 67/242 (27%), Positives = 99/242 (40%), Gaps = 11/242 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +IL GG GTRL PIT  + K L+P+ +KP + Y L  L   GI   ++         
Sbjct: 1   MQAVILVGGLGTRLRPITYDIPKALVPLRNKPFMGYTLDFLRGGGIEGAVLSLGYLPDP- 59

Query: 61  FQRLLGDGSEF-GIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK 119
            QR + +  +  G  +EYA +  P G A        FL   P  +VL  ++  G      
Sbjct: 60  IQRYIDERGDLDGFSVEYAVEERPLGTAGGIKNAARFLQDGP-VVVLNGDVLTGMDLRKA 118

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYD 177
           +    +    AT+    V DP  +G+VE D +       EKP   +  +N    G+Y  +
Sbjct: 119 IELHRSTGALATITLTSVEDPTAYGLVEVDHDMMVRRFIEKPSPDEVTTNLVNAGVYVLE 178

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
            +V+E      P  R       I     E   L   +      W D GT  S + AS  V
Sbjct: 179 PEVLEMI----PPGREVSIEREIFPRLQERRQLYAHV--SSSYWKDIGTPRSYLAASHDV 232

Query: 238 QT 239
            +
Sbjct: 233 LS 234


>UniRef50_Q5CTS3 Mannose-1-phosphate guanylyltransferase n=2 Tax=Cryptosporidium
           RepID=Q5CTS3_CRYPV
          Length = 425

 Score =  194 bits (494), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 51/253 (20%), Positives = 92/253 (36%), Gaps = 11/253 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK IIL+GG G+RL P+T    K ++ + + P+I + ++     GI EI++    +    
Sbjct: 30  MKAIILSGGYGSRLRPLTLTKPKSIVELCNIPIIEFQIAQFASIGITEIIVALNYKANEL 89

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
              L      + +++  + +  P G A    + + FL  +    V   +I         L
Sbjct: 90  IPTLKIIEDRYAVKVHLSIEEKPLGTAGPIKLAQDFLKEDEPFFVCNSDIICNFPLREML 149

Query: 121 RHVAARTEG----ATVFGYQVMDPERFGVVEFDDNFRAIS-LEEKPKQPKSNWAVTGLYF 175
                +         +   QV DP +FGVV  D+N   +    EKPK    ++   G+Y 
Sbjct: 150 DLYHKKNSDSECNGVILIKQVSDPSKFGVVLHDENTLIVEKFIEKPKDFVGDFINAGIYI 209

Query: 176 YDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVE--LLGRGFAWLDTGTHDSLIEA 233
              ++++  K  +           +  +   +  L            W D G     +  
Sbjct: 210 LSKRILDLIKPNQ----QVSIEKDVFPIMASSNTLYCNKFFTNNDNIWADIGNPKDFLLG 265

Query: 234 STFVQTVEKRQGF 246
           S       K    
Sbjct: 266 SKLFMEFLKSNSI 278


>UniRef50_A8A970 Nucleotidyl transferase n=1 Tax=Ignicoccus hospitalis KIN4/I
           RepID=A8A970_IGNH4
          Length = 355

 Score =  194 bits (494), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 85/259 (32%), Positives = 126/259 (48%), Gaps = 6/259 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+GIILA G G+RL P+T  V K L+P+  KP++ Y +  L   G+   + +        
Sbjct: 1   MEGIILAAGKGSRLRPLTLTVPKPLIPVAGKPLVQYGIEQLRGVGVERAV-VVVGWLGEL 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F+ +LGDGS  G++ EY  QP   G+A A        N     LV   +  F   +  K 
Sbjct: 60  FKEVLGDGSALGMRFEYVLQPKRLGVAHAIHTAIVNANVRSPFLVYFGDNVFDDEWVKKF 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFY-DSK 179
             V    +   V    V DP RFGV    ++ R +   EKP++P SN+A+TGLY + D +
Sbjct: 120 NSVDEEFDAFVVLAK-VEDPRRFGVPVI-ESGRIVKFVEKPERPPSNYALTGLYAFRDPE 177

Query: 180 VVEYA-KQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
             E    ++KPS RGE EIT +   Y+  G      +  G+ W DTG  + LIEA  F+ 
Sbjct: 178 QYESCFSELKPSWRGEYEITDLLNCYIRRGYDVKYAVVEGW-WKDTGVPEDLIEAMKFIL 236

Query: 239 TVEKRQGFKIACLEEIAWR 257
             +     + +   E+  +
Sbjct: 237 EKKLIHKVEGSVEGEVVGK 255


>UniRef50_A9CZR8 Nucleotidyl transferase n=1 Tax=Hoeflea phototrophica DFL-43
           RepID=A9CZR8_9RHIZ
          Length = 346

 Score =  194 bits (493), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 59/242 (24%), Positives = 95/242 (39%), Gaps = 12/242 (4%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQR 63
           +I+AGG GTRL P+T  V K L+ +  +P+I   +  L+  G+  I +          + 
Sbjct: 109 VIMAGGLGTRLRPLTEKVPKPLISVGGRPLIDTIVDRLVAQGLSNITLCVNY-LGHMLEE 167

Query: 64  LLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHV 123
            LGDGS +G +  Y  +    G A A  + +     E S  V+  +I             
Sbjct: 168 HLGDGSRYGARFTYVRENKRMGTAGALSLLD--KRPETSFFVMNGDILTSVDLMAMRSFH 225

Query: 124 AARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEY 183
                 AT+          FGVV+  D  R   L EKP+   +     G+Y ++ +V+++
Sbjct: 226 QENNSLATMAVNNFSYEVPFGVVDVRDR-RITGLSEKPQ--CNFLVNAGIYLFEPEVLDH 282

Query: 184 AKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEKR 243
               +  +       S     ++     V    R   WLD G  D L  A+     V   
Sbjct: 283 VPSDEFFDMN-----SFFDRLIDLDKPIVAFPVRE-HWLDIGRPDDLERANNTFSAVAGG 336

Query: 244 QG 245
           +G
Sbjct: 337 KG 338


>UniRef50_B5GDG2 Nucleotide phosphorylase n=1 Tax=Streptomyces sp. SPB74
           RepID=B5GDG2_9ACTO
          Length = 360

 Score =  194 bits (492), Expect = 4e-48,   Method: Composition-based stats.
 Identities = 60/239 (25%), Positives = 102/239 (42%), Gaps = 11/239 (4%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            I+L GG GTRL P+T    K ++P    P + + L+    AG+  I++ T+      F+
Sbjct: 25  AILLVGGKGTRLRPLTVNTPKPMVPAAGVPFLAHQLARARAAGVEHIVLATSY-LAEVFE 83

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFL--NGEPSCLVLGDNIFFGQGFSPKL 120
              GDGS FG++++Y  +  P G   A     + L    E   LV   +I  G   +  +
Sbjct: 84  PYFGDGSAFGLRVDYVTEREPLGTGGALRNVASHLESGPEDPVLVFNGDILTGLDINALV 143

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPK---SNWAVTGLYFYD 177
                     ++   +V DP  FG+V  D + R ++  EKP+ P+   ++    G Y + 
Sbjct: 144 DTHVTAGADVSLHLSRVDDPRAFGLVPTDASGRVLAFLEKPQTPEEIVTDQINAGAYVFR 203

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTF 236
            +V++      P  R            L +G     ++   + WLD GT  + +  S  
Sbjct: 204 RRVIDAI----PGGRPVSVERETFPGLLASGAHLQGMVDSTY-WLDLGTPQAFVRGSAD 257


>UniRef50_A3DMT9 Nucleotidyl transferase n=11 Tax=Thermoprotei RepID=A3DMT9_STAMF
          Length = 426

 Score =  193 bits (491), Expect = 6e-48,   Method: Composition-based stats.
 Identities = 72/282 (25%), Positives = 123/282 (43%), Gaps = 12/282 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREI--LIITTPEDK 58
           MK IILA G G RL PIT    K L+P+  KP++ + L  L  AGI E+  ++I     K
Sbjct: 2   MKAIILAAGKGLRLRPITETRPKPLIPVLCKPLLQWQLEAL--AGINEVDEVVIVVSYLK 59

Query: 59  GYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSP 118
              ++ +G  +    ++   +Q    G   A +        +   L++  +IF    ++ 
Sbjct: 60  EQVEQFVGKLN-MPFKITLLDQGEELGTGDAILKAIRKRGIDGKILIIYGDIFLK-DWNE 117

Query: 119 KLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDS 178
             + V  R +   + G +V +P  +GV+  D+      + EKP  P SN    GLYF D+
Sbjct: 118 LKQLVLTRKDF--IVGVEVDNPSDYGVIVVDEYNSFKGIIEKPAIPPSNLINAGLYFLDA 175

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           + +     ++ S RGELE T I       G            W+D G    L++A+    
Sbjct: 176 RDILKHSDIELSPRGELEFTDILSSMARNGVEIKVYQLSKGKWIDIGKPWHLLDANKM-- 233

Query: 239 TVEKRQGFKIACLEEIAWRNG--WLDDEGVKRAASSLAKTGY 278
            +E      I  +E  A  +G  ++ +  + ++ + +    Y
Sbjct: 234 ALENISTKIIGSIEPGAHVHGRVFVGEGTIVKSGTYIEGPVY 275


>UniRef50_UPI0001C16C8D Mannose-1-phosphate guanyltransferase CBS pair associated n=1
           Tax=Raphidiopsis brookii D9 RepID=UPI0001C16C8D
          Length = 349

 Score =  193 bits (490), Expect = 7e-48,   Method: Composition-based stats.
 Identities = 54/236 (22%), Positives = 101/236 (42%), Gaps = 12/236 (5%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQR 63
           +I+AGG GTRL+P+T+   K LL +  KP++   +      G ++I +    + +   + 
Sbjct: 125 VIMAGGLGTRLYPLTKDRPKPLLTVGGKPILEIIIENFAEQGFKQIFLSVNYKAE-MIED 183

Query: 64  LLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHV 123
              +G ++G+++ Y  +    G A A  +     N     +V+  +I     F   L+  
Sbjct: 184 YFKNGDQWGVEISYLREKERLGTAGALSLLPKKPNL--PIIVMNGDILTRTRFDNLLQFH 241

Query: 124 AARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEY 183
             +   AT+   +      +GVV  D   +  S+EEKP Q    +  +G+Y     V++Y
Sbjct: 242 ELQGVLATMAVREYDLQVPYGVVRVDGT-KIKSIEEKPVQHF--FVNSGIYALSPGVLDY 298

Query: 184 AKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
                       ++ S+ Q  +     T     R + WLD G    L  A+  +++
Sbjct: 299 VPS-----GTFFDMPSLFQQLVVDTRTTAAYPLREY-WLDIGRMSDLERANEELRS 348


>UniRef50_B6BGD8 Nucleotidyl transferase n=1 Tax=Campylobacterales bacterium GD 1
           RepID=B6BGD8_9PROT
          Length = 353

 Score =  193 bits (490), Expect = 8e-48,   Method: Composition-based stats.
 Identities = 47/239 (19%), Positives = 100/239 (41%), Gaps = 12/239 (5%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K +++ GG GTRL P+T  + K LL + +KP++   +      G ++ ++    + +   
Sbjct: 121 KVVLMVGGLGTRLRPLTDDMPKPLLKVGNKPILETIIDNFSKYGFKDFILSVNYKSE-MI 179

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLR 121
           ++  G+GS FG+ +EY ++    G A A  +    L  +    V+  ++     +   L 
Sbjct: 180 KKHFGNGSRFGVNIEYVQEDKRMGTAGALSLMREKLKDD--FFVMNGDLLTNVNYEHLLN 237

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVV 181
           +       AT+   +      +GVV  + N    S+ EKP      +   G+Y      +
Sbjct: 238 YHLNDNAVATMCVKEYDFQIPYGVVNIEHNH-ITSISEKPIH--KFFVNAGIYMLSPSTL 294

Query: 182 EYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           E+    +       ++ ++    ++    ++    R + WLD G  +   +A+     +
Sbjct: 295 EFIPNNEF-----FDMPTLFDNLIQHKQKSISFPIREY-WLDIGEIEEYKKANIEYLDI 347


>UniRef50_Q3AQC4 Glucose-1-phosphate thymidylyltransferase n=12 Tax=Chlorobiaceae
           RepID=Q3AQC4_CHLCH
          Length = 349

 Score =  193 bits (490), Expect = 8e-48,   Method: Composition-based stats.
 Identities = 73/257 (28%), Positives = 116/257 (45%), Gaps = 18/257 (7%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK II   G GTRL P T    K LL +  KP+I + +  L+ AGI E ++I        
Sbjct: 25  MKAIIPVAGVGTRLRPHTFSHPKVLLNVAGKPIIGHIMDKLIAAGITEAIVIVGYLGDMI 84

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFL-NGEPSCLVLGDNIFFGQGFSPK 119
            + LL +   + I+  +  Q    GL  A  + + ++   EP  ++LGD IF      P 
Sbjct: 85  EEWLLQN---YDIKFTFVTQSELLGLGHAISMCKPYIPEDEPLFIILGDTIF-DVNLEPV 140

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDS- 178
           L     ++  +T+   +V+DP RFGV    +N   + L EKP  P SN A+ GLY     
Sbjct: 141 L-----KSTCSTIGVKEVVDPRRFGVAVT-ENGAIVKLVEKPDTPVSNLAIVGLYLLQHS 194

Query: 179 ----KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
               K ++Y  +   + +GE ++T   Q  L+ G        +G  W D G  ++L+  +
Sbjct: 195 AALFKSIDYLIEHNITTKGEYQLTDALQRLLDEGEKFTTFPVQG--WYDCGKPETLLATN 252

Query: 235 TFVQTVEKRQGFKIACL 251
             + +          C+
Sbjct: 253 EILLSDNPPSKTYPGCI 269


>UniRef50_Q18G10 Glucose-1-phosphate thymidylyltransferase n=5 Tax=Halobacteriaceae
           RepID=Q18G10_HALWD
          Length = 403

 Score =  192 bits (489), Expect = 9e-48,   Method: Composition-based stats.
 Identities = 66/273 (24%), Positives = 114/273 (41%), Gaps = 21/273 (7%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +ILA G GTR+ P+T   +K +LP+  +P+  +     + AG   ++ +   E +  
Sbjct: 1   MQTVILAAGKGTRMRPLTESTAKPMLPVVGEPIAAHTAQAAINAGASRLIFVIGYEAES- 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   G+ S     + YA Q    G A A    +  L  +P  ++ GDN++         
Sbjct: 60  VKEYFGE-SYQDTPVAYATQTEQRGTADAVRAAKAELTEDPFVVLNGDNLYDVSSLESLY 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNF--------RAISLEEKPKQPKSNWAVTG 172
                     ++   +V +P  +GV+E  ++         R   + EKP  P SN    G
Sbjct: 119 ------VSAPSIGTVRVENPSAYGVLEITEDNESESDMSKRVSGVVEKPANPPSNRINAG 172

Query: 173 LYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIE 232
            Y +  +       V PSER E E+T   Q   E+ ++T   + R   WLD G     +E
Sbjct: 173 AYAF-PEAARGWLDVDPSERDEYELTDTLQQTCESVSVTPVDIDR---WLDVGRPWEYLE 228

Query: 233 ASTFVQTVEKRQGFKIACLEEIAWRNGWLDDEG 265
           A+ +  + E R  F+     +   R   + +  
Sbjct: 229 ANEWKLS-ECRPRFEGDVSPDADLRGSVVVESD 260


>UniRef50_Q4UEZ4 GDP-mannose pyrophosphorylase, putative n=2 Tax=Theileria
           RepID=Q4UEZ4_THEAN
          Length = 389

 Score =  192 bits (489), Expect = 9e-48,   Method: Composition-based stats.
 Identities = 51/245 (20%), Positives = 96/245 (39%), Gaps = 11/245 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +ILAGG GTR+ P+T  V K L+   ++P+I + +     AG   ++I  T      
Sbjct: 1   MKSVILAGGYGTRIRPLTLSVPKPLVDFCNRPVIEHQIQACKNAGFDHVIIAVTEHH-NI 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFL---NGEPSCLVLGDNIFFGQGFS 117
            + +     ++ I+++++ + +P G A    + +  +   +     +V   +I       
Sbjct: 60  TEPIKNLAEKYSIRIDFSTESTPLGTAGPLRLAKDLICSDDDSDDFVVFNSDIICNYPLK 119

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYD 177
             L     ++   T+    V +   FGV+  D+N    S  EKPK   SN    G+Y   
Sbjct: 120 ELLESHRKKSAKVTIMVTTVENSSEFGVILHDENGLIKSFLEKPKNATSNTINAGVYVLS 179

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
            +V+++      S             YL+    +  +      W D G     +      
Sbjct: 180 KEVLDHIPLKNYSIE-----KQFFPKYLK--YNSSYIYKLNGFWSDIGKPTGYLNGQNLF 232

Query: 238 QTVEK 242
            +  +
Sbjct: 233 LSHVQ 237


>UniRef50_Q0G1T6 Nucleotidyl transferase n=1 Tax=Fulvimarina pelagi HTCC2506
           RepID=Q0G1T6_9RHIZ
          Length = 344

 Score =  192 bits (489), Expect = 1e-47,   Method: Composition-based stats.
 Identities = 56/235 (23%), Positives = 93/235 (39%), Gaps = 12/235 (5%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQR 63
           I++AGG G RL P+T  + K +LP+  +P++   L      G R   I          + 
Sbjct: 120 ILMAGGLGKRLRPLTETMPKPMLPVGGRPLLEIILRNFTDQGFRNFTICLNY-MANVVRD 178

Query: 64  LLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHV 123
             GDGS F   + Y ++    G A A  +           +++  ++     F   +R  
Sbjct: 179 YFGDGSAFDSSITYVQEEEALGTAGALTLLPE--RPSRPFIIMNGDLLTTLHFESVIRFH 236

Query: 124 AARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEY 183
                 AT+   + +    +GVV  DD  R +S+EEKP    S +   G+Y      +E 
Sbjct: 237 DEHLADATLCAREHLVQIPYGVVRSDD-ARLLSIEEKPT--ISQYVNAGIYVLSPNSLEL 293

Query: 184 AKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
                   R   ++T +    LE     V    R + W+D G    L +A +  +
Sbjct: 294 LAY-----REHADMTQLFDRILERNMKAVVFPMREY-WIDVGQIGDLQKARSDFR 342


>UniRef50_Q3Z925 Glucose-1-phosphate thymidylyltransferase n=5 Tax=Dehalococcoides
           RepID=Q3Z925_DEHE1
          Length = 393

 Score =  192 bits (488), Expect = 1e-47,   Method: Composition-based stats.
 Identities = 70/276 (25%), Positives = 113/276 (40%), Gaps = 16/276 (5%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           + +ILA G G RL P T   SK +L I  KP++ Y +  L   GIR+I+++   + +  F
Sbjct: 3   QAVILAAGEGQRLRPFTSSKSKVMLSIAGKPLLEYVIESLARNGIRDIILVVGYKRERIF 62

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLR 121
               GDG   G+++ Y  QP+  G A A       + G+   ++ GD +           
Sbjct: 63  -DYFGDGGHLGVEITYVSQPNQLGTAHALKQTRDKIRGD-FLVLNGDQLISPATIG---D 117

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVV 181
            V    +   V      DP R+GVV      R  S+EEKP   KSN   TG+Y + ++V 
Sbjct: 118 FVKEPPQAVMVKAINGEDPRRYGVVSSSGR-RLTSIEEKPSIAKSNLINTGIYSFSTRVF 176

Query: 182 EYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVE 241
           +Y  +        L+I  + Q  +    L + +      WLD      ++  +  V    
Sbjct: 177 DYIAE-------HLDIPMVLQSMI-KDGLDIRVAESRGVWLDIVYPWDMLSLNAVVSDTL 228

Query: 242 KRQGFKIACLEEIAWRNG-WLDDEGVKRAASSLAKT 276
           K  G        +  +    +    V R+ S +   
Sbjct: 229 K-PGVAGTIESGVVMKGPVLIGKNTVIRSNSYITGP 263


>UniRef50_Q3SPZ3 Nucleotidyl transferase n=1 Tax=Nitrobacter winogradskyi Nb-255
           RepID=Q3SPZ3_NITWN
          Length = 346

 Score =  192 bits (487), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 55/237 (23%), Positives = 110/237 (46%), Gaps = 12/237 (5%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQR 63
           +++AGG G+RL P+T  + K L+ + +KP++   L+  + +G  +  I    + +   + 
Sbjct: 120 VLMAGGLGSRLRPLTDDLPKPLIKVGNKPILETVLNGFIKSGFGKFFISVNYKAE-MIRE 178

Query: 64  LLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHV 123
             GDGS +G++++Y  +    G A A  +            V+  ++     F   L++ 
Sbjct: 179 YFGDGSAWGVEIDYLVESDRLGTAGALSLIPE--RPTRPFFVMNGDLLTTVNFEQMLKYH 236

Query: 124 AARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEY 183
                  T+   +      FGVV+F ++ R + + EKP Q    +   G+Y  D +V++Y
Sbjct: 237 LEHQAFTTICVREHAITVPFGVVDF-EDHRILGIREKPTQ--KFFVNAGVYLLDPEVLDY 293

Query: 184 AKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
               +      +++ ++ +  +E G  +V    R + W+D G  D L +AS   Q +
Sbjct: 294 IGATEA-----VDMPTLIERTIERGKRSVAFPLREY-WIDVGRLDDLQKASDEFQRI 344


>UniRef50_UPI0001C315B1 Nucleotidyl transferase n=1 Tax=Conexibacter woesei DSM 14684
           RepID=UPI0001C315B1
          Length = 329

 Score =  192 bits (487), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 59/274 (21%), Positives = 108/274 (39%), Gaps = 21/274 (7%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++LA G GTRL P+T  + K ++P+ D+P++ + + +L   G  EI +         
Sbjct: 1   MKAMVLAAGLGTRLRPLTYEIPKPMVPVLDRPVMAHIVDLLERHGYGEI-VANLHYFPDT 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GD      ++ Y E+P   G A        FL  + + L++  +       +  +
Sbjct: 60  IRAYFGD------RIVYREEPELLGTAGGVRNCADFL-ADDTFLIISGDALTDIDLTRFV 112

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
           +        AT+   +V D   FGVV  DD  R    +EKP+  +  S+    G+Y ++ 
Sbjct: 113 KRHKEAGGVATLAVKRVADTREFGVVLHDDTGRITGFQEKPEPAEALSDLGNCGIYLFEP 172

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGT----HDSLIEAS 234
           ++ +Y       +        +    L A ++   +      W D G+     D   +A 
Sbjct: 173 RIFDYFPDQPFVD----WANDVFPALL-AQDVPFHIHEIDEYWNDVGSLGELKDGTFDAM 227

Query: 235 TFVQTVEKRQGFKIACLEEIAWRNGWLDDEGVKR 268
                +E     +    + IA     LD   +  
Sbjct: 228 RGELHLE--VEGEPVAEDVIAGEGTSLDGATLIE 259


>UniRef50_Q2LPS3 Glucose-1-phosphate adenylyltransferase n=3 Tax=cellular organisms
           RepID=Q2LPS3_SYNAS
          Length = 240

 Score =  192 bits (487), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 58/244 (23%), Positives = 105/244 (43%), Gaps = 14/244 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++LAGG G RL P T+ + K L+PI D P++   L  + +AGI  +++         
Sbjct: 1   MKAVVLAGGKGARLAPYTKILPKPLMPIGDMPILEVLLRQMKVAGIDHVILTVGH-LSEL 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +    DGS+FG+ + Y+ +  P G A    + +     + + LV   ++         +
Sbjct: 60  LRAFFQDGSQFGVDISYSYEKCPLGTAGPISLIDGL---DETFLVTNGDVLTTLSLRELI 116

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                +   AT+  +Q       GV++++ N+      EKP          G+Y ++ KV
Sbjct: 117 GFHREQKAAATIAVHQRQTKIDLGVIQWNGNYEVKGYIEKP--VYDYTVSMGVYVFEPKV 174

Query: 181 VEYAKQVKPSERGEL-EITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           + Y         GE  +   + +  + AG   V     G+ W D G  D    AS   ++
Sbjct: 175 LSYIPH------GEYLDFPDLVKKLIAAGEKVVGYRFHGY-WEDLGRPDDYERASRDFES 227

Query: 240 VEKR 243
           + ++
Sbjct: 228 MREQ 231


>UniRef50_B0BZ78 Nucleotidyl transferase protein n=5 Tax=Cyanobacteria
           RepID=B0BZ78_ACAM1
          Length = 323

 Score =  192 bits (487), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 62/292 (21%), Positives = 110/292 (37%), Gaps = 28/292 (9%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +I+AGG GTRL P+T    K +LP++++P + + +      G+ +IL+    +    
Sbjct: 1   MQAVIIAGGKGTRLSPLTLRSPKPMLPLFERPFLSWMVERCKAVGLTDILMNIRYQ-ATQ 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            Q   GDG +FG+++ Y  +      A A  + E F  GEP  +V   +I         +
Sbjct: 60  IQEYFGDGQKFGVKIRYVIEKEALDTAGAMKLAEPFYTGEP-LVVFNADILTNLNLQALM 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDD--------NFRAISLEEKPKQPKS-----N 167
           +        AT+   +V DP  FG+VE  D             S  EKP   ++     +
Sbjct: 119 QAHEQTQAQATIALARVADPTAFGLVELTDITASEHSSTGTIQSFREKPTPEEAATLGID 178

Query: 168 WAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTH 227
               G Y  + ++       +P         ++    L         +     W+D GT 
Sbjct: 179 TVNAGTYVLNPEIFAQYPADQPL----SFERTVFPNLLSNQQKISGFV-WEGYWMDLGTP 233

Query: 228 DSLIEASTFVQTVEKRQGFKI-ACLEEIAWRNG--WLDDEGVKRAASSLAKT 276
                A   +      QG       E +  R    W+ +  +    + ++  
Sbjct: 234 AKFYGAHLDIL-----QGKMPFPLPEAMEERQPQVWVANNAIIDPQAKISGP 280


>UniRef50_B8D6C9 Glucose-1-phosphate thymidylyltransferase n=1 Tax=Desulfurococcus
           kamchatkensis 1221n RepID=B8D6C9_DESK1
          Length = 427

 Score =  191 bits (486), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 65/244 (26%), Positives = 107/244 (43%), Gaps = 6/244 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +ILA G+G RL PIT    K L+PI  KP++ + L  L      + ++I T      
Sbjct: 1   MKAVILAAGNGIRLKPITETRPKPLIPILCKPLLDWHLDRLAAVSFIDEVVIVTGYMGDI 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  +        ++ + EQ  P G   A + G   +  +   L++  +IF      P++
Sbjct: 61  IRAHVMS-RRLPFKVRFVEQGEPRGTGDAVVKGIEGMGSDDDVLIIYSDIFTPVNIIPEI 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
               A   G  + G +V +P  +GV+  + N+    + EKP  P S     G+Y   ++ 
Sbjct: 120 ----AGESGNIIVGSEVDNPSDYGVLINEGNYF-KGVVEKPMNPPSRLVNAGIYKLRTRD 174

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           +     +KPS RGELE T +       G            W+D G    +IEA+    T+
Sbjct: 175 ILDNSDIKPSPRGELEFTDVLNNMSRRGVKIRIYKLPRALWIDIGKPWHVIEANKMALTM 234

Query: 241 EKRQ 244
            K++
Sbjct: 235 VKKE 238


>UniRef50_C7P380 Nucleotidyl transferase n=20 Tax=Halobacteriaceae
           RepID=C7P380_HALMD
          Length = 253

 Score =  191 bits (486), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 63/231 (27%), Positives = 101/231 (43%), Gaps = 7/231 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++LA G GTRL P+T    K ++ +  KP++ +    L+  G  E+L++   + K  
Sbjct: 1   MKAVVLAAGEGTRLRPLTEDKPKGMVEVAGKPILTHCFEQLIELGADELLVVVGYK-KQV 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                 D  E G+ + YA Q    GLA A +  E  +  +   L+LGDNIF        +
Sbjct: 60  IINHFEDEFE-GVPITYAHQRDQKGLAHALLTVEEHI-DDDFMLMLGDNIF-QANLRDVI 116

Query: 121 RHVAARTEGATVFGYQV--MDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDS 178
                    A     +V   +  R+GV + +       + EKP  P SN  +TG Y +  
Sbjct: 117 NRQREERADAAFLVEEVPWEEASRYGVCDTNKYGEIEEVVEKPDDPPSNLVMTGFYTFTP 176

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDS 229
            +      V+PS R E EI+    + L +G  T++ +       D G  + 
Sbjct: 177 AIFHACHLVQPSNRDEYEISDAIDLLLHSGR-TIDAIRMDGWRTDIGYPED 226


>UniRef50_Q26CD7 Putative nucleoside diphosphate sugar pyrophosphorylase n=1
           Tax=Flavobacteria bacterium BBFL7 RepID=Q26CD7_9BACT
          Length = 347

 Score =  191 bits (486), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 59/241 (24%), Positives = 105/241 (43%), Gaps = 12/241 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           ++ +I+AGG G RL P+T  + K +LP+ DKP+I + +  L+  GI++I I         
Sbjct: 119 LECMIMAGGRGKRLSPLTDSIPKPMLPLGDKPIIEHNIDRLISFGIQKIYISVKY-LGEQ 177

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDGS  GIQ+EY  +  P G A A  + + F       L++  ++F    F    
Sbjct: 178 LEAYFGDGSSKGIQIEYIWEDEPLGTAGALKLVDKF--NTDYVLLMNSDLFTSVNFEEMY 235

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
             +        V   +      + V E D N +  + +EKP     +    G+Y     +
Sbjct: 236 LQLLQENADMVVASTEYKVDVPYAVFETDGN-KVKAFKEKPSYIYQS--NAGIYILKRSL 292

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           ++   + +       +IT + +  ++ G   V     GF W+D G      +A  F++  
Sbjct: 293 IDQMTKNEY-----CDITDVMEKLVQDGGKLVYDPILGF-WIDIGKPSDYKQAQEFIKHF 346

Query: 241 E 241
           +
Sbjct: 347 K 347


>UniRef50_Q1J1Y9 Nucleotidyl transferase n=2 Tax=Deinococcus RepID=Q1J1Y9_DEIGD
          Length = 365

 Score =  191 bits (485), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 74/239 (30%), Positives = 115/239 (48%), Gaps = 9/239 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+ILA G G+RL P++ G  K  +PI   P+I + +  +  AG+ E+ ++T+  ++  
Sbjct: 21  MKGVILAAGRGSRLFPVSAGRPKHAVPIAGVPIIAWAVRAVREAGVEEVAVVTSSNNEAA 80

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +    D       L +  Q  P G   A +    FL G P+ L LGDN+F     +P  
Sbjct: 81  LREATRDEG----PLTFLRQEEPRGTGDAVLAARAFLEGSPALLYLGDNLFAD-PLTPLT 135

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
             +  +   A +   QV DP  +GV    DN    +L+EKP  P S+ A  G++ +   V
Sbjct: 136 EAL--QDADAALGVKQVPDPSAYGVAAVRDNL-LTNLDEKPAAPASDLAACGVFAFHPHV 192

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           +E   +++PS RGE+E        + AG     +   GF W D GT   L+ AS    +
Sbjct: 193 LEEVARLEPSVRGEIEFPQALLRVIAAGGRVRAVTFPGF-WSDAGTPADLLSASAHFLS 250


>UniRef50_Q1Q6W7 Putative uncharacterized protein n=2 Tax=Bacteria
           RepID=Q1Q6W7_9BACT
          Length = 632

 Score =  190 bits (483), Expect = 4e-47,   Method: Composition-based stats.
 Identities = 60/305 (19%), Positives = 125/305 (40%), Gaps = 23/305 (7%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +ILAGG GTR+  +++ + K ++ I +KP++ Y + +     + +I+++T  + +  
Sbjct: 1   MKVVILAGGKGTRMGSLSQNIPKPMINIANKPILQYQIEIAKRFNLTDIILLTGYKGE-V 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   G+G  +G+ +    +  P G A A    E +L+ +   LV   ++         +
Sbjct: 60  VEDYFGNGENWGVNISCYRETIPLGTAGAVKEVEDYLHDD--FLVFYGDVIMDIDLKSVI 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQ---PKSNWAVTGLYFYD 177
           R+   R   AT+  +    P    ++E ++  + I+   KP +      N     LY   
Sbjct: 118 RYHMKRKPIATLVVHPNDHPYDSDLIEVNNEGKVITFHSKPHKQDIFIRNLVNAALYILS 177

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIE----- 232
            +++ +  +   S+ G      I    +  G +        +   D GT + L E     
Sbjct: 178 PRIMNFLPKGTYSDFG----KDIFPKLVNDGEIIYAYNTPEYI-KDIGTLERLEEVERDI 232

Query: 233 ASTFVQTVEKRQGFKIACLE-------EIAWRNGWLDDEGVKRAASSLAKTGYGQYLLEL 285
            S  +  + K+   K   L+       EI       + E +    +++ K    +YL  +
Sbjct: 233 VSGKLYRLNKKNKRKAIFLDRDGVLNYEIDLLRTPEELELLPDVPNAIKKINTSEYLSVV 292

Query: 286 LRARP 290
           +  +P
Sbjct: 293 VTNQP 297


>UniRef50_A3DNE2 Nucleotidyl transferase n=8 Tax=Thermoprotei RepID=A3DNE2_STAMF
          Length = 233

 Score =  190 bits (483), Expect = 4e-47,   Method: Composition-based stats.
 Identities = 61/235 (25%), Positives = 99/235 (42%), Gaps = 11/235 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M  +ILAGG G RL P T  + K L+ + +KP++ + +  L   G  E +++     +  
Sbjct: 1   MMAVILAGGFGKRLRPYTEEIPKPLVSVAEKPILEWQIEWLKQYGFNEFVLLVGYRKEKI 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  +G G + G+++ Y  +  P G   A    E  L+ E   LVL  +I          
Sbjct: 61  IEH-IGSGGKLGVKVTYVVEDEPLGTGGAIKNAEHILSKEEKFLVLNGDILTNLNPMKLF 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
             +    E   V    +  P  +GV+E  D+ +     EKPK  +  W   G+Y      
Sbjct: 120 EKLDEHPEFVAVIA-SIPLPSPYGVLEIKDS-KVTGFVEKPKL-QDYWINAGIYAMKPSA 176

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAST 235
           ++Y       ERG+LE T+   M  +     V+    G  W    T+  L EA+ 
Sbjct: 177 LKYFP-----ERGDLERTAFPAMAKDGVLGAVKY--TGVFWKSVDTYKDLEEATK 224


>UniRef50_Q6MME9 Mannose-1-phosphate guanyltransferase n=1 Tax=Bdellovibrio
           bacteriovorus RepID=Q6MME9_BDEBA
          Length = 350

 Score =  189 bits (480), Expect = 9e-47,   Method: Composition-based stats.
 Identities = 48/237 (20%), Positives = 97/237 (40%), Gaps = 12/237 (5%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K +++AGG G RL P+T  V K LL +  +P++   L      G    + +     +   
Sbjct: 121 KVVLMAGGFGKRLSPLTDSVPKPLLRVGGRPILETILMRFCELGFYNFIFVVNYRAE-MI 179

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLR 121
           +    +G ++G  +EY  +  P G      +            V+  +I     F+  L 
Sbjct: 180 KEYFQNGEKWGATIEYLHEEIPLGTCGGLSLLSE--KPSSPIFVMNGDILTRANFAEMLD 237

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVV 181
             A+    AT+   + +    +GVV+ + +   +S+EEKPK+    +   G+Y    + +
Sbjct: 238 FHASSMATATMVVREHIIEIPYGVVKVNGD-EIVSIEEKPKE--KTFVNAGIYILSPEAL 294

Query: 182 EYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           EY  + +       ++ S+     +   L      + + W+D G  +   +A +  +
Sbjct: 295 EYIPRDQF-----YDMPSLFMSLKDKEKLIQSFKLKDY-WVDIGRLEDFHKAQSDFE 345


>UniRef50_B7XJS8 Mannose-1-phosphate guanyltransferase n=1 Tax=Enterocytozoon
           bieneusi H348 RepID=B7XJS8_ENTBH
          Length = 329

 Score =  189 bits (480), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 53/237 (22%), Positives = 108/237 (45%), Gaps = 12/237 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +IL GG GTRL+P+T+   K L+P  +KP+I Y + +L+ AGI+ I++           
Sbjct: 6   AVILVGGKGTRLYPLTKTRPKPLIPFLNKPIIEYQIDLLVEAGIQRIILALNYFSDQIKH 65

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
           + L   + + I++ Y+ +  P G A    + E ++NG  + +V+  +I+     +  +  
Sbjct: 66  KALEWKANYNIEIIYSHELEPLGTAGPLKLAEKYINGN-AFIVMNADIYTSINLTSMITE 124

Query: 123 VA-ARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDSK 179
               +   A + G +V +P+++G++E   N    +  EKP      +N    G+Y ++  
Sbjct: 125 FKTKKNYDAILLGVEVDNPDKYGLIEI-KNGTVTNFIEKPSYTNGPTNIINGGIYIFNRN 183

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTF 236
           ++ + +    S   E     I    ++   +T  +      W D G  +  ++    
Sbjct: 184 ILNFIELKYVSIEKE-----IFPQLVQNQKMT--IFHFNGIWCDIGVPNEYLKGQKK 233


>UniRef50_A6C2H5 Nucleoside-diphosphate-sugar pyrophosphorylase n=1 Tax=Planctomyces
           maris DSM 8797 RepID=A6C2H5_9PLAN
          Length = 377

 Score =  189 bits (480), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 61/253 (24%), Positives = 104/253 (41%), Gaps = 13/253 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +I+AGG G RL P+T  + K L+ +   P+I   +  +  AG+  I +          +
Sbjct: 127 ALIMAGGEGRRLLPLTENLPKPLVEVGGMPLIERQVRRIAHAGVNRIYVAVNY-LAEMIE 185

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
             LGDGS FG+++ Y  +P   G A +  +    L+G    L++  ++F    F   L  
Sbjct: 186 SHLGDGSRFGVEIHYLREPKKLGTAGSLSLITEKLDG--PLLLMNGDVFTSINFQYLLDF 243

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
            +      TV          +GV++ +  F    LEEKP Q        G+Y    + V 
Sbjct: 244 HSKHQPLITVAAIDYHVEIPYGVIKTEGPFAIC-LEEKPSQ--QFLCNAGIYALSPEAVS 300

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEK 242
                +        +T + +  L   +         + W D GTH  L +A + ++ V +
Sbjct: 301 RVPPNQI-----FNMTDLIESGLSQKDGVAVFPVHEY-WSDIGTHAELDKARSELKIVRE 354

Query: 243 RQGFKIACLEEIA 255
             G  +   +EIA
Sbjct: 355 TLG-DLEESDEIA 366


>UniRef50_A0ADR0 Putative nucleoside-diphosphate-sugar pyrophosphorylase n=1
           Tax=Streptomyces ambofaciens ATCC 23877
           RepID=A0ADR0_STRAM
          Length = 254

 Score =  189 bits (480), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 62/260 (23%), Positives = 102/260 (39%), Gaps = 12/260 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ ++LAGG G RL P T  V K L+PI   P+++  L+ L  AG   + +         
Sbjct: 1   MRAVVLAGGEGRRLRPATLTVPKPLMPIDGIPILHIILTQLKNAGFTRVTLSLGYR-AHM 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   G     G++L+++ +  P G A    +   F   E S LV+  ++     F+   
Sbjct: 60  IRASFGGNRWSGLELDFSLEEEPLGTAGPLALLPPF---EESVLVMNADLLTDVDFADLW 116

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
            H       AT+           GVVE D+  R     EKP+   S     G+Y  +  +
Sbjct: 117 SHHKKSRAAATIALSPQDIDVAHGVVELDEERRVTDFREKPR--LSFLVSGGIYVLEPSL 174

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           + +        RG  ++ ++       G      +  G  W D GT + L  A+T  +T 
Sbjct: 175 LRFLP-----PRGRHDMPTLLDHARAHGERVEGYVIEG-DWRDIGTPEQLDLATTAFRTD 228

Query: 241 EKRQGFKIACLEEIAWRNGW 260
             R   +    E  A    +
Sbjct: 229 RARYLGRRGVAELCAGTGAF 248


>UniRef50_Q9YCT0 Glucose-1-phosphate thymidylyltransferase n=1 Tax=Aeropyrum pernix
           RepID=Q9YCT0_AERPE
          Length = 355

 Score =  189 bits (479), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 76/236 (32%), Positives = 120/236 (50%), Gaps = 7/236 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +KG+ILA G G+RL P T    K L+P+  KP+I Y +  L+   +R+I ++        
Sbjct: 2   VKGLILAAGEGSRLRPFTFSRPKHLIPLLGKPIIQYAIDDLVSINVRDIGVVVGY-FGDK 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIG-ETFLNGEPSCLVLGDNIFFGQGFSPK 119
            +  LG+ S FG +  Y  Q    G+A A     +     +   + LGDNI  G G S  
Sbjct: 61  IKEFLGEDSRFGAKFTYIVQKKRLGIAHAIYRAIKQGFIDKEFIVYLGDNILSG-GISRH 119

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFY-DS 178
           ++          +   +V DP RFG+     + + + L EKP++  S+ AV G+Y + D 
Sbjct: 120 VKSWGEAGSEVHILLTKVRDPGRFGIAVL-RDGKILKLVEKPQEHISDLAVVGVYMFRDP 178

Query: 179 KVVEYA-KQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEA 233
           ++V  A   +KPS RGE EIT + Q +++ G      L  G+ W D GT++ L++A
Sbjct: 179 ELVAKAFSTLKPSWRGEYEITDLIQWFVDKGYKVTFSLVTGW-WKDVGTYEGLLDA 233


>UniRef50_Q7U909 Putative sugar-phosphate nucleotide transferase n=1
           Tax=Synechococcus sp. WH 8102 RepID=Q7U909_SYNPX
          Length = 352

 Score =  188 bits (477), Expect = 2e-46,   Method: Composition-based stats.
 Identities = 58/233 (24%), Positives = 95/233 (40%), Gaps = 11/233 (4%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQR 63
           +I+AGG G RL P+T    K +LP++ KPM+ + L  L   G + ++I            
Sbjct: 130 VIMAGGKGKRLMPLTANTPKPMLPVHGKPMLEHILDRLREDGFKNVIISVNY-LSERITS 188

Query: 64  LLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHV 123
              DGS+F + + Y  +  P G A A   G      E   +V   +I  G  +S  L + 
Sbjct: 189 YFQDGSKFDMNISYLYEDKPLGTAGALS-GLDSKTRENPVIVTNADILSGISYSDLLIYF 247

Query: 124 AARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEY 183
              T    +          FGVV+ + +    ++ EKP          GLY  D+K+++ 
Sbjct: 248 RRNTSNGLMAVRTQEWQNPFGVVQSNGSH-ITNIIEKPTHYYQ--VNAGLYVLDNKLLDL 304

Query: 184 AKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTF 236
                       ++  + +M LE  NL +++      WLD G       A+  
Sbjct: 305 LTPNSY-----CDMPDLFRMGLE-INLNLQVYPLHEQWLDIGRPKDYDIANKE 351


>UniRef50_B9LW43 Nucleotidyl transferase n=5 Tax=Halobacteriaceae RepID=B9LW43_HALLT
          Length = 402

 Score =  188 bits (477), Expect = 2e-46,   Method: Composition-based stats.
 Identities = 72/295 (24%), Positives = 123/295 (41%), Gaps = 15/295 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M G++LA G GTR+ P+T    K LLP+ D+ ++       +      ++   T      
Sbjct: 1   MYGVVLAAGRGTRMRPLTDRRPKPLLPVGDRSLLEQVFDTAVDVVDEFVV--VTGYRGDA 58

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  +G+ S     + Y EQ    G A A       ++ +   LVL  ++         L
Sbjct: 59  IRESIGE-SYRDRPVTYVEQEEAKGTAHAIAQAAPVVDDD--FLVLNGDVVVDASLPRVL 115

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
               A  +G  V   +V+DP  +GV+    +     + EKP  P +N A  G Y +  +V
Sbjct: 116 ----ANADGPAVAATEVIDPRAYGVLSTAADGSLTKIVEKPANPPTNLANVGCYAFTPEV 171

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            EY  +   SERGE EIT+  ++ L+ G+  +++      WLD G    L+EA+    T 
Sbjct: 172 FEYIDRTPESERGEYEITTTIELLLDDGHR-IDVAPYVGTWLDVGRPWELLEANELALTE 230

Query: 241 EKRQGFKIACLEEIAWRNG--WLDDEGVKRAASSLAKTGYGQYLLELLRARPRQY 293
                     +E+    +G   ++D  + R+ + +        + E     P  Y
Sbjct: 231 LGSDEAIAGTVEKGVHLHGSVVVEDGALVRSGAYIEGPVL---IREGAEVGPNAY 282


>UniRef50_C5A4I2 Sugar-phosphate nucleotydyltransferase n=9 Tax=Thermococcaceae
           RepID=C5A4I2_THEGJ
          Length = 420

 Score =  188 bits (477), Expect = 3e-46,   Method: Composition-based stats.
 Identities = 66/253 (26%), Positives = 110/253 (43%), Gaps = 8/253 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++LA G G RL P+T    K +L + ++P+I Y +  L    + E +I+   E +  
Sbjct: 1   MKAVVLAAGKGERLKPLTDDRPKVILKVANRPIIEYVMENLYPF-VDEFIIVVRYEKEKI 59

Query: 61  FQRLLGDGSEFGIQ-LEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK 119
            + L   G EFG + + Y EQ   +G A+A       +  E   +  GD  F  +     
Sbjct: 60  IETL---GDEFGGKPVTYVEQRPGEGTAKAVESAREHVGDEEFIVANGDIYFEVEAIKEL 116

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSK 179
           +         A +      D   FG VE  +  R + + EKP +    +A  G+Y +   
Sbjct: 117 VSAFRREKADAALVLKHFEDLSHFGKVEVKE-GRVVGILEKPGKVPG-YANLGIYLFRPD 174

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           V E+  +   SERGE EIT    + ++AG      +   + W D G   +L+E + ++  
Sbjct: 175 VFEFIGETPLSERGEYEITDTINLMIKAGKKVAYAVYSDY-WNDIGRPWNLLELNEYLLK 233

Query: 240 VEKRQGFKIACLE 252
            + R   +    E
Sbjct: 234 TKLRHEIRGTVEE 246


>UniRef50_A7NP68 Nucleotidyl transferase n=2 Tax=Roseiflexus RepID=A7NP68_ROSCS
          Length = 262

 Score =  187 bits (476), Expect = 3e-46,   Method: Composition-based stats.
 Identities = 64/249 (25%), Positives = 104/249 (41%), Gaps = 10/249 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +ILA G+GTRL P+T    K + PI  +P++ + L  L   G+ E  +         
Sbjct: 1   MKALILAAGAGTRLRPLTDTCPKPMAPIAGQPLLAWTLEWLRRYGVTEAAL-NLHHLPDV 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  LGDGS FGI+L YA +    G A A      F   + + LV+  ++         +
Sbjct: 60  VRAGLGDGSRFGIRLRYAVEEELRGTAGALHNFPGFF--DQTFLVIYGDLLLDIDLDDLI 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK-QPKSNWAVTGLYFYDSK 179
           R    +    T+   +   P   G+++ D   R     EKP      + A  G+Y  + +
Sbjct: 118 RFHRQQGAIMTLALKRTDTPHSQGMIDIDTTGRVKRFIEKPAVWDGGDTANAGVYVCEPE 177

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           +V +      S+ G      I    L AG        RG+  LD GT  +  +A    + 
Sbjct: 178 IVSWTPPGF-SDFG----HDIIPALLHAGVPVYGRPLRGYL-LDIGTPAAYEQAQQEWRA 231

Query: 240 VEKRQGFKI 248
            ++ +G + 
Sbjct: 232 RQEARGERG 240


>UniRef50_C9LPM2 Nucleotidyl transferase family enzyme n=1 Tax=Dialister invisus DSM
           15470 RepID=C9LPM2_9FIRM
          Length = 232

 Score =  187 bits (475), Expect = 4e-46,   Method: Composition-based stats.
 Identities = 51/241 (21%), Positives = 93/241 (38%), Gaps = 13/241 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPED--- 57
           MK  +LA G GTRL P+T  V K L+PI  +P++ + + +     I EILI T       
Sbjct: 1   MKAFLLAAGLGTRLRPLTWTVPKCLVPIQGRPLLAWWMDLFEQHRISEILINTNYLPDPV 60

Query: 58  KGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
           + + +    + +   ++L  + +    G     +I   F+  E    +   +       S
Sbjct: 61  RKFIKEY--NQTRGKVKLVESYEKELLGSGGTVLINRNFVENEEDFFICYADNLTNADLS 118

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYD 177
             +          T+  +   +P   G+  ++   +     EKPK PKS+ A  G+Y  +
Sbjct: 119 SMMDFHKKNHALLTMGLFHTNNPTGCGIAVYNKEGKITEFVEKPKYPKSDLANAGIYVVN 178

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
            K+ +Y       + G   +  +                + +  LD GT  +  EA    
Sbjct: 179 KKIYDYIPNKSFVDFGGDVLPELVGKM-------YGYPIKEYL-LDVGTWPNYEEAQEKW 230

Query: 238 Q 238
           +
Sbjct: 231 R 231


>UniRef50_B5HPZ4 Nucleotide phosphorylase n=1 Tax=Streptomyces sviceus ATCC 29083
           RepID=B5HPZ4_9ACTO
          Length = 365

 Score =  187 bits (475), Expect = 4e-46,   Method: Composition-based stats.
 Identities = 68/245 (27%), Positives = 106/245 (43%), Gaps = 13/245 (5%)

Query: 1   MK-GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKG 59
           M+  IIL GG GTRL P+T    K LL +     I + ++ LM AG+  ++  T+     
Sbjct: 1   MQEAIILVGGKGTRLRPLTNHTPKPLLGVAGSSFIRHQIAKLMDAGVEHVVFATSY-LAS 59

Query: 60  YFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNG--EPSCLVLGDNIFFGQGFS 117
            F+    D +   +++ YA +  P G   A       L+G  + S LVL  +I  G   +
Sbjct: 60  LFEEEFKDFTR-ELKISYAVEEVPLGTGGAIRNAARLLDGPADASVLVLNGDILSGVDLN 118

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPK---SNWAVTGLY 174
             L   A R    T+   +V DP  FG+V  D + R +S  EKPK  +   ++    G Y
Sbjct: 119 ALLERHAEREAEVTLHLTRVPDPRAFGLVPTDGSGRVLSFLEKPKTAEECVTDKINAGCY 178

Query: 175 FYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
            +   V++      P++R E+ +       L A    V        W D GT  + +  S
Sbjct: 179 VFRRSVLDAI----PADR-EVSVEQETFPQLVARGGRVFGHTTDDYWRDLGTPLAFVHGS 233

Query: 235 TFVQT 239
             + T
Sbjct: 234 ADLVT 238


>UniRef50_B0VGT1 Putative Mannose-1-phosphate guanylyltransferase n=1 Tax=Candidatus
           Cloacamonas acidaminovorans RepID=B0VGT1_9BACT
          Length = 231

 Score =  187 bits (475), Expect = 5e-46,   Method: Composition-based stats.
 Identities = 57/239 (23%), Positives = 102/239 (42%), Gaps = 11/239 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +IL+GG G+RL P T  + K LLPI +K ++   +  L   G   I + T  + + Y
Sbjct: 1   MKAVILSGGLGSRLKPFTEVIPKPLLPIGEKAVLEIQIEHLKNNGFDHIFLATNYKSE-Y 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   G+GS++G++L  +++  P G A    + +  LN EP  LV+  +I     +    
Sbjct: 60  IENFFGNGSKYGVKLSISKEEKPLGTAGPVKLLQNQLNNEP-FLVMNGDILTLLPYRKLY 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
               ++    T+    +  P +FG +  + +F    +EEKP        + G+Y +  ++
Sbjct: 119 EFACSKETLLTIATKDIYTPFQFGNIHTEGDF-VTGIEEKPN--IKTTILAGIYIFKPEI 175

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           +            +L I       LE          + + WLD G      +A    + 
Sbjct: 176 LNLIPDNTMYGMDKLIID-----MLERRLPISHYPIQEY-WLDIGQVGDYEKAQEIYKE 228


>UniRef50_B1HN58 Mannose-1-phosphate guanyltransferase 2 n=5 Tax=Bacteria
           RepID=B1HN58_LYSSC
          Length = 350

 Score =  187 bits (474), Expect = 5e-46,   Method: Composition-based stats.
 Identities = 50/237 (21%), Positives = 97/237 (40%), Gaps = 12/237 (5%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQR 63
           +++ GG GTRL P+T    K +L + +KP++   +      G    +     + K   Q 
Sbjct: 122 VLMLGGLGTRLRPLTNDTPKPMLRVGNKPILETIIEGFKQYGYTNFIFSVNYK-KEVIQD 180

Query: 64  LLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHV 123
              +G  F + +EY E+    G A A  + +          V+  ++     F   ++  
Sbjct: 181 YFQNGEAFDVTIEYIEEDKKMGTAGALSLLK--KRPTKPFFVMNGDLLTQINFDQLMQFH 238

Query: 124 AARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEY 183
                 AT+   +      FGV+E +       ++EKP     ++   G+Y  +  V++Y
Sbjct: 239 MEHESVATMCVREFEYQIPFGVIETNGTDLVT-IKEKPIH--RSFVNAGIYLLNPDVLDY 295

Query: 184 AKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
             Q +       ++ S+ +  +E  + T     R + WLD G  D   +A+  V+ +
Sbjct: 296 IPQDEF-----YDMPSLFEKLIEKNSKTSVFPIREY-WLDIGQIDDFNKANNEVKEL 346


>UniRef50_A8MDH4 Nucleotidyl transferase n=6 Tax=Thermoproteaceae RepID=A8MDH4_CALMQ
          Length = 237

 Score =  187 bits (474), Expect = 5e-46,   Method: Composition-based stats.
 Identities = 50/235 (21%), Positives = 103/235 (43%), Gaps = 14/235 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M  +ILAGG G RL P+T    K L+ +  +P++ + +  L   G+ +I++         
Sbjct: 3   MFAVILAGGFGKRLRPLTDDRPKPLVEVAGRPILAWQIDWLREQGVTDIILAVGYLGGKI 62

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F   +GDGS+FG+++ Y+ +  P G   A      ++N +   +V   ++         +
Sbjct: 63  F-DYIGDGSQFGVRVYYSVEREPLGTGGAVRNALKYINDDGFIVV-NGDVITNLRIGKLM 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
             +  R     +    +  P  +G+V+ D++   ++ +EKP+ P       G+Y   + +
Sbjct: 121 DSL-QRGVIGAIALTPLKSP--YGIVQVDEDGFILNFQEKPQLP--YLINAGVYALRTSI 175

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAST 235
            +Y       E+G++E+ +  ++  +   + +        W    T   L EA  
Sbjct: 176 RDYLP-----EKGDIEVYTFPRLAKDKKLIGITY--NDVYWKSIDTLKDLEEADK 223


>UniRef50_A9W818 Nucleotidyl transferase n=2 Tax=Rhizobiales RepID=A9W818_METEP
          Length = 238

 Score =  186 bits (473), Expect = 7e-46,   Method: Composition-based stats.
 Identities = 60/234 (25%), Positives = 97/234 (41%), Gaps = 12/234 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +I AGG GTRL P T  + K L+PI  KP++   +  L    I E+ I T       
Sbjct: 1   MKAVIQAGGRGTRLMPYTSVLPKPLMPIGAKPVLELLVKWLRRNAIEELYITTGY-LGHL 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDG ++G+ + Y E+  P G   A  + E  L  + + LVL  ++          
Sbjct: 60  IRSFCGDGRQWGLHIVYTEETEPLGTIGALTLLEKHL--DETFLVLNGDVLTDLSLRTFT 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
               A  +  T+      +   FGV+E D +    S  EKP    +N    G+Y  + ++
Sbjct: 118 GIHRAHGQPFTIATACRSNKLDFGVIE-DQDGVVTSFSEKP--VLTNSVSMGIYCMEPEI 174

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
           +++  +  P               L A N+ + +      WLD G  +   +A 
Sbjct: 175 LDHIPRGMPFG------ADDLAHCLLAKNVPIHVYKHQGLWLDIGRVEDFHKAQ 222


>UniRef50_B1BCE9 Nucleotidyl transferase n=2 Tax=Clostridium RepID=B1BCE9_CLOBO
          Length = 345

 Score =  186 bits (472), Expect = 8e-46,   Method: Composition-based stats.
 Identities = 59/233 (25%), Positives = 94/233 (40%), Gaps = 12/233 (5%)

Query: 5   ILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQRL 64
           ILAGG GTRL P+T  + K +L I DKPM+   +      G +  +I    + +   +  
Sbjct: 121 ILAGGLGTRLRPLTEKLPKPMLKIGDKPMLERIIKQFRGYGFKNFIISINYKGE-VIEDY 179

Query: 65  LGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHVA 124
             DGSEF + +EY  +    G A +  + +  LN +   +V+  +I  G  F   L +  
Sbjct: 180 FKDGSEFDVNIEYVREEKKLGTAGSISLAKNKLNKD--FIVINGDILTGIDFEELLNYHE 237

Query: 125 ARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEYA 184
                 T           +GV+   D     SLEEKP      +  +G+Y     VV+Y 
Sbjct: 238 ENKYDITAGARNYEMKVPYGVMVMKDEL-IQSLEEKPTYNF--YINSGVYVLSKDVVKYI 294

Query: 185 KQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
              K     E  +T + +  +             + W D G  +   +A+  V
Sbjct: 295 PDNK-----EYNMTDLIEDVINNNGRCGAYNITEY-WSDIGHIEDYKKANEDV 341


>UniRef50_D0KYG3 Nucleotidyl transferase n=30 Tax=cellular organisms
           RepID=D0KYG3_HALNC
          Length = 353

 Score =  186 bits (472), Expect = 9e-46,   Method: Composition-based stats.
 Identities = 57/239 (23%), Positives = 97/239 (40%), Gaps = 11/239 (4%)

Query: 5   ILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQRL 64
           ++AGG GTRL P+T    K +L +  KPM+ + L  L+  G     I      +   +  
Sbjct: 125 LMAGGFGTRLRPLTDSCPKPMLKVGGKPMLEHILQDLIDYGFYRFYISVHYLREQVIEH- 183

Query: 65  LGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHVA 124
             DGS FG+ ++Y  + +P G A    +        P  +V+  +I     +   L+   
Sbjct: 184 FKDGSRFGVSIQYIHEDTPLGTAGCLGLLPRDAVQRP-IIVVNGDIMTRVNYEALLQDHD 242

Query: 125 ARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEYA 184
             T  ATV   Q      +GV+E  ++ R  ++ EKP Q    +   G+Y    +VV   
Sbjct: 243 RHTPAATVCTRQYDFQVPYGVIEH-EDQRITNITEKPTQHF--FVSAGIYVLAPQVVHSM 299

Query: 185 KQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEKR 243
                     +++  + +  + AG          + WLD G  +    A     +V +R
Sbjct: 300 AADTR-----VDMPDLLKSEITAGRSVRMFPVHEY-WLDIGRMNDFELAQNDAASVLQR 352


>UniRef50_C5VTI3 Nucleotidyl transferase n=1 Tax=Clostridium botulinum D str. 1873
           RepID=C5VTI3_CLOBO
          Length = 349

 Score =  185 bits (471), Expect = 1e-45,   Method: Composition-based stats.
 Identities = 57/233 (24%), Positives = 94/233 (40%), Gaps = 12/233 (5%)

Query: 5   ILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQRL 64
           ILAGG GTRL P+T  + K +L I  KPM+   +      G    +I    + +   +  
Sbjct: 125 ILAGGLGTRLRPLTENIPKPMLKIGGKPMLQRIIEQFKGYGFVNFIISLNYKGE-IIENY 183

Query: 65  LGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHVA 124
             DGS F + ++Y  +    G A +  + +   N +   LV+  +I  G  F   L+H  
Sbjct: 184 FKDGSNFDVNIQYVREEKKLGTAGSINLAKEKFNKD--FLVINGDILTGIDFEVMLKHHI 241

Query: 125 ARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEYA 184
                 T           +GV+   +N    SLEEKP      +  +G+Y     V+ Y 
Sbjct: 242 ENKFDITAGARNYEMRVPYGVM-ITENKIIKSLEEKPTYNF--YINSGVYVLSKNVINYI 298

Query: 185 KQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
            +       E  +T + +  ++AG          + W D G  +   +A+  V
Sbjct: 299 PENT-----EYNMTDLIEDVIKAGGRCGTYNITEY-WSDIGHIEDYKKANEDV 345


>UniRef50_A7ZFS2 Nucleotidyl transferase n=3 Tax=Proteobacteria RepID=A7ZFS2_CAMC1
          Length = 348

 Score =  185 bits (470), Expect = 2e-45,   Method: Composition-based stats.
 Identities = 45/239 (18%), Positives = 97/239 (40%), Gaps = 12/239 (5%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           + I++ GG GTRL P+T+ + K +L + +KP++   +      G   I +          
Sbjct: 121 RVILMVGGLGTRLRPLTKDMPKPMLKVGNKPILQTIVEKFAEYGFVNITMCVNFN-ASII 179

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLR 121
           +   GDG EFG+ ++Y  +    G A A  + +          V+  ++     F     
Sbjct: 180 RDYFGDGKEFGVNIDYVLEQKRMGTAGALSLLKE--RPSEPFFVMNGDLLTNVNFEHIFN 237

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVV 181
           +       AT+   +      +GVV+ +DN +  ++ EKP Q    +   G+Y    +++
Sbjct: 238 YHTLHKATATMCVREYDYEVPYGVVKMNDN-KITAIAEKPVQ--KFFVSAGIYMLSPEIL 294

Query: 182 EYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           +   Q +       ++ ++ +  +      +      + W+D G  +   +A+     +
Sbjct: 295 DLIPQDEF-----YDMPTLFEKAIAQDKNVISFPIHEY-WIDIGRLEEYQKANEEYAKI 347


>UniRef50_B4SDB4 Nucleotidyl transferase n=1 Tax=Pelodictyon phaeoclathratiforme
           BU-1 RepID=B4SDB4_PELPB
          Length = 352

 Score =  185 bits (470), Expect = 2e-45,   Method: Composition-based stats.
 Identities = 51/235 (21%), Positives = 89/235 (37%), Gaps = 16/235 (6%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQR 63
           +I+AGG GTRL P T    K +L +  KPM+ + +      G    ++          + 
Sbjct: 127 VIMAGGMGTRLRPHTENCPKPMLSVSGKPMLEHIIERAKQEGFSHFVLAINY-LGHVIEN 185

Query: 64  LLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPS--CLVLGDNIFFGQGFSPKLR 121
             GDG+   ++++Y ++ SP G A A       LN  P+    V   ++     +   L 
Sbjct: 186 YFGDGTCLQVRIDYLKEKSPLGTAGAL----GLLNPWPTLPFAVTNGDVMTDIHYGELLD 241

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVV 181
                   AT+          FGVV+ D     I  EEKP     +    G+Y  + + +
Sbjct: 242 FHTRHNAAATMAVRVHEWQHPFGVVQTDG-IDIIGFEEKPVH--RSHINAGVYVLEPEAL 298

Query: 182 EYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTF 236
            + ++         ++ ++ +        T         WLD G  + L  A+  
Sbjct: 299 CFLEKNVR-----CDMPALFERLQAKEKRTAAYPIHE-PWLDVGRQEDLTRANMD 347


>UniRef50_A9FF13 Putative sugar-phosphate nucleotide transferase n=1 Tax=Sorangium
           cellulosum 'So ce 56' RepID=A9FF13_SORC5
          Length = 236

 Score =  185 bits (470), Expect = 2e-45,   Method: Composition-based stats.
 Identities = 61/244 (25%), Positives = 103/244 (42%), Gaps = 11/244 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++LAGG G+RL P T  + K L+PI D  ++   L  L  AG+ ++++    +    
Sbjct: 1   MKAVVLAGGKGSRLRPYTALIPKPLMPIGDHTIVEILLRQLARAGVTDVVMCVGHQ-AAL 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            + ++G+GS +G+++ Y  + +P G      + E  L      LV+  +I     F+   
Sbjct: 60  IEAVVGEGSRYGLRIAYQREDTPLGTVGPLRVIERDLP--ERFLVMNGDILSDLDFTALH 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           R   +     TV   +       GV++   + R +S  EKP    + W   G+Y     V
Sbjct: 118 RTGESAGSPLTVAVCERASKIDLGVLDLGADGRVVSFREKPTY--TFWVSMGIYAMSRDV 175

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           + +  + +P          +    L AG        RG  WLD G  D   EA    +  
Sbjct: 176 LPFIPEGRPFG-----FDDLMHALLGAGEPVATFPFRG-HWLDIGRSDDFAEAQEEFEKN 229

Query: 241 EKRQ 244
            +R 
Sbjct: 230 RQRY 233


>UniRef50_B8IAD4 Nucleotidyl transferase n=1 Tax=Methylobacterium nodulans ORS 2060
           RepID=B8IAD4_METNO
          Length = 238

 Score =  185 bits (469), Expect = 2e-45,   Method: Composition-based stats.
 Identities = 56/239 (23%), Positives = 91/239 (38%), Gaps = 10/239 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK I+LAGG GTRL P +  + K L+PI + P++   L  +   GI E+++         
Sbjct: 1   MKAIVLAGGKGTRLMPYSALIPKPLMPIGEMPILELLLRQMKHHGISEVILAVNH-LHHL 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDGS  G+++ Y+ +    G +         L+ +   LV   ++     F   +
Sbjct: 60  IRSFFGDGSSLGLKITYSVEDKALGTSGPITANLDALSDD--FLVSNGDLLTNLDFGAMM 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           R   AR   AT+          +G +  D +       EKP    S  A  GLY    K 
Sbjct: 118 RQHIARQVAATIATQSRAMQADYGALTVDKDNLIREYREKP--IFSFEASMGLYVLSKKA 175

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           V     V        ++  + +  +EA    +        W+D G  +    A      
Sbjct: 176 VRPHLPVNTF----FDMPDLIKSLIEADQPVLSY-NETCNWIDIGKPNDYGRAQERFAA 229


>UniRef50_C7NR86 Nucleotidyl transferase n=4 Tax=Halobacteriaceae RepID=C7NR86_HALUD
          Length = 439

 Score =  184 bits (468), Expect = 2e-45,   Method: Composition-based stats.
 Identities = 70/293 (23%), Positives = 120/293 (40%), Gaps = 17/293 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +ILA G GTR+ P+T    K +LP+  +P++ +     + AG  E++++   E +  
Sbjct: 47  MQTVILAAGQGTRMGPLTESTPKPMLPVAGRPLVAHVADAAVDAGASELVVVVGYEAEA- 105

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GD     + + +A Q    G A A       L+G    ++ GDN++         
Sbjct: 106 VRSFFGDTYR-DVPVTFAVQAEQAGTADAVRAARPELDG-AFAVLNGDNLYDPAAVEQLF 163

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                     ++  Y+V DP  +GVV   D      + EKP  P + +A TG Y +    
Sbjct: 164 E------SAPSLATYEVDDPSNYGVVSITD-GIVTDIVEKPADPPTTYANTGAYVFPEAA 216

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           +++   V  SERGE EIT +    ++A  +T   L R   W D G    L+EA+  +   
Sbjct: 217 IDWL-DVPESERGEYEITDVVAQVIDAHEVTPVPLSR---WRDVGRPWELLEANETLLAE 272

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRARPRQY 293
                      ++   R   + + G       + +     Y+       P  Y
Sbjct: 273 LDGT-VDGTVSDDAELRGTVVVEAGATIEPGVVIEGPV--YVSRGASVGPNAY 322


>UniRef50_A0L542 Nucleotidyl transferase n=2 Tax=Proteobacteria RepID=A0L542_MAGSM
          Length = 351

 Score =  184 bits (468), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 50/235 (21%), Positives = 96/235 (40%), Gaps = 11/235 (4%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQR 63
           +++AGG G+RL  +TR   K LL +  +P++   +   +  G  +  +    + K   + 
Sbjct: 125 VLMAGGLGSRLGELTRDCPKPLLHVGKQPILEMIIENFVSYGFHKFYLAVNYK-KEMIKA 183

Query: 64  LLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHV 123
             GDGS  G+++EY E+    G A    +       +    V+  ++     F   L + 
Sbjct: 184 YFGDGSRLGVRIEYLEEEQRLGTAGPLSLMPEA--PKDPFFVMNGDLLTRIHFGRVLDYH 241

Query: 124 AARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEY 183
             +   AT+   QV +   +GVV+  +N R   + EKP      +  TG+Y  +  V+  
Sbjct: 242 RQQQADATMCVRQVEETLPYGVVDLGENHRLNGITEKPVN--RYFVNTGIYLLEPHVLPI 299

Query: 184 AKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
             +         ++  + +   + G   V      + W+D G      +A   V+
Sbjct: 300 IPK-----GQFFDMPDLFRSLADEGKHPVAFPFLEY-WMDIGQVGDFHQACRDVK 348


>UniRef50_Q0W734 Nucleotidyltransferase family protein n=2 Tax=Euryarchaeota
           RepID=Q0W734_UNCMA
          Length = 231

 Score =  184 bits (468), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 62/241 (25%), Positives = 106/241 (43%), Gaps = 17/241 (7%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK  IL GG G RL PIT  + K ++P+  KP++ Y + +L   G+R+I+ +     +  
Sbjct: 1   MKAFILCGGRGERLKPITDKIPKPMVPVAGKPILEYQVDLLKKHGVRDIVFLVGWYGEA- 59

Query: 61  FQRLLGDGSEFGIQLEYAEQP--SPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSP 118
            +   GDGS+FGI+ EY+ +   +  G A      +  ++G  + +V+  +I      S 
Sbjct: 60  IEAYFGDGSKFGIRAEYSYEDPNNRLGTAGPIKAAKDKVDG--AIIVMNGDIISNTNISE 117

Query: 119 KLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDS 178
            +     +    T+    +  P  FG+++ + +       EKP  P       GLY  ++
Sbjct: 118 IVAFHTKKKCLGTINMINM--PSPFGIIDLNGDH-ITQFREKPVLPFK--MNAGLYVIEA 172

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
            VV+    V     G +E     ++  E           G  W D GTH  L + +  VQ
Sbjct: 173 DVVDMMPAV-----GSIETDVFPKIAAEG--KLCGYDSTGIYWSDVGTHKDLEKVTKDVQ 225

Query: 239 T 239
           +
Sbjct: 226 S 226


>UniRef50_A2C5W2 Nucleoside-diphosphate-sugar pyrophosphorylase n=3
           Tax=Cyanobacteria RepID=A2C5W2_PROM3
          Length = 320

 Score =  184 bits (468), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 53/238 (22%), Positives = 93/238 (39%), Gaps = 12/238 (5%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQR 63
           +I+AGG G RL P+T    K +L +  KPM+   L   + +G  E         K     
Sbjct: 95  VIMAGGKGMRLRPLTEDCPKPMLLVGGKPMLKILLEQFIASGFEEFYFSVNY-LKDKIIN 153

Query: 64  LLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHV 123
              +G  +G+ + Y  +  P G A +  +  + +      +V+  ++         LR  
Sbjct: 154 HFENGERWGVNIRYINEDKPLGTAGSLKLLPSNIKR--PFIVINGDVLTRLNTIQLLRFH 211

Query: 124 AARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEY 183
                 AT+   +      FGVV+ D        +EKP+         G+Y  +  ++E 
Sbjct: 212 IDHDALATICVREYEMKVPFGVVQVDG-VELKGFKEKPR--IRQLVNAGIYVINPALIES 268

Query: 184 AKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVE 241
            K  +  +  EL +   N+      +  V +      WLD G  +SL EA    + ++
Sbjct: 269 IKDGQVIDMPELLLNESNE------SRRVTVYPIHEYWLDVGRPESLEEAHATWEELK 320


>UniRef50_Q30U75 Nucleotidyl transferase n=3 Tax=Proteobacteria RepID=Q30U75_SULDN
          Length = 234

 Score =  184 bits (466), Expect = 4e-45,   Method: Composition-based stats.
 Identities = 57/232 (24%), Positives = 92/232 (39%), Gaps = 11/232 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ ++LA G G+RL PIT  + K L+PI  KP++ Y L  L  AGI E LI T       
Sbjct: 1   MRALLLAAGIGSRLRPITNTIPKCLVPINGKPLLEYWLKNLSEAGIDEFLINTHHLHVQV 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                 + S++  ++    +          +    F + EP  LV  DN+ F   F   +
Sbjct: 61  --EEFIESSKYRDKITLVYEKKLLNTGSTLLTNRAFFDNEPFMLVHADNLSFC-DFGKFI 117

Query: 121 RHVAARTEGA--TVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDS 178
                R      T+  ++  +P   G+VE D+        EK K P SN A   +Y  ++
Sbjct: 118 NAHKNRPNNCDITMMLFKSDNPSSCGIVELDNRGIVQEFYEKVKNPPSNLANGAVYICEA 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSL 230
            + ++ + +   E         +   L      +          D GT +S 
Sbjct: 178 SLFDFLECLDKKE------IDFSNDVLPKYLGKINTYFNNTYHRDIGTIESY 223


>UniRef50_A1WSE0 Nucleotidyl transferase n=1 Tax=Verminephrobacter eiseniae EF01-2
           RepID=A1WSE0_VEREI
          Length = 351

 Score =  184 bits (466), Expect = 5e-45,   Method: Composition-based stats.
 Identities = 55/232 (23%), Positives = 92/232 (39%), Gaps = 12/232 (5%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQR 63
           +++AGG G RL PIT+ + K ++P+  KP++ + L  L   G RE             + 
Sbjct: 126 VVMAGGKGQRLLPITQDLPKPMVPVGGKPILEWILLRLRHYGFREFSFAINY-LGHMIED 184

Query: 64  LLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHV 123
             GDGS F  ++ Y  +    G A A  +           +V   +I  G  F   +   
Sbjct: 185 YFGDGSAFDCRIRYIREKEFLGTAGALSLLPP--GDAHPLVVTNGDILSGIDFGHLVDFH 242

Query: 124 AARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEY 183
           AA    ATV          +GV++  D      + EKP     +    G+Y    +V+  
Sbjct: 243 AAGGRSATVCARAHRVEVPYGVLQMSDGC-LQGIVEKPVHD--HLISAGIYVLSPQVLPR 299

Query: 184 AKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAST 235
             Q +  +  EL ++ I++ +       + +      W+D G HD L     
Sbjct: 300 IPQGQALDMPELLLSLIDEHH------KIGVFVLEDEWVDVGRHDDLERVRR 345


>UniRef50_D2LMS4 Nucleotidyl transferase n=3 Tax=Aciduliprofundum boonei T469
           RepID=D2LMS4_9EURY
          Length = 400

 Score =  182 bits (463), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 64/242 (26%), Positives = 112/242 (46%), Gaps = 14/242 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+  ILA G GTR+ P+T    K L+P+ +KP+I + L  L+ AGI +I I+   E +  
Sbjct: 1   MRAFILAAGEGTRMWPLTDTRPKPLIPLANKPIIEHILDALVEAGIEKISILIGYEGRQI 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +R     S  G +++Y  Q    G   A +    +   +   L+L  +++F +     +
Sbjct: 61  AERY--GYSYKGAKIDYVYQNERRGTGDAVLYASKY--NDEKFLILNGDLYFEKSAISDI 116

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                      V G    + E +G++  D+N     + EK     S     G+Y +  ++
Sbjct: 117 LGH-----DNAVLGVYKDNAESYGLLIGDEN--LEEIREK-VPSSSGLVNAGVYVFHREI 168

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            EY K+V+ S RGE+E T    M+++  +  V+++     WLD G    L++A+      
Sbjct: 169 FEYIKRVELSPRGEIEFTDAINMFVKEHD--VKIVKYNGLWLDIGYPWHLLDATKAYLEK 226

Query: 241 EK 242
            K
Sbjct: 227 MK 228


>UniRef50_C7NV90 Nucleotidyl transferase n=1 Tax=Halorhabdus utahensis DSM 12940
           RepID=C7NV90_HALUD
          Length = 397

 Score =  182 bits (462), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 57/230 (24%), Positives = 98/230 (42%), Gaps = 7/230 (3%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            I+LA G GTRL P+T    K +LP  + P++ Y L  L+ AG+ E++++   E +   Q
Sbjct: 6   AIVLAAGEGTRLRPLTHNRPKPMLPAGNTPILEYVLDALVEAGVEELVLVVGYE-RDRVQ 64

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
             +G     G  + Y +Q    G   A +  +  + G    +V GD +            
Sbjct: 65  NHVGPTYR-GRPVTYVDQTKQLGTGHALLQAQAAVEGS-FLVVNGDTLIDPTIVEDVTDQ 122

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
                  AT+      DP  +G V  +D     +L EKP   +  +   G+Y ++  + E
Sbjct: 123 FEESEPRATLAVLDGPDPTDYGAVLVEDGL-VTNLVEKPDAGEYRYINAGVYAFEPSIFE 181

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIE 232
             ++  P E GEL +T      ++  + +V  +     W+D      L+E
Sbjct: 182 MIERT-PREAGELALTDTLARLID--DRSVGAVETDGTWVDATYPWDLLE 228


>UniRef50_B5EDT7 Nucleotidyl transferase n=5 Tax=Bacteria RepID=B5EDT7_GEOBB
          Length = 240

 Score =  182 bits (462), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 55/243 (22%), Positives = 99/243 (40%), Gaps = 12/243 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +ILAGG GTRL P T  + K L+PI + P++   +  L+  G   I +    + K  
Sbjct: 1   MRAVILAGGRGTRLRPYTVVLPKPLMPIGEYPILEVIVRQLVHCGFTHITMAVNHQAK-I 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            Q   G+G  +GI ++Y+ +  P        + +         LV+  +I     F    
Sbjct: 60  IQAFFGNGERWGITIDYSLETKPLSTMGPLRLIDDLPEN---FLVMNGDILTDLNFREFH 116

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
            +        T+  YQ +    +GV++ +   +    EEKP+         G+Y  +   
Sbjct: 117 DYHVRVKNNFTIAAYQRVLKSEYGVLKINRQKKLCGFEEKPEYLLD--VSMGVYMVNRDT 174

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           + +     P     L +       L  G+     + +GF WLD G  D  ++A     ++
Sbjct: 175 MRHIPADTPYGFDHLMLD-----LLAEGHPASVKIHKGF-WLDIGRPDDYMQAIEEFDSL 228

Query: 241 EKR 243
           + +
Sbjct: 229 KGK 231


>UniRef50_Q5HT82 Nucleotidyltransferase family protein n=11 Tax=Campylobacter
           RepID=Q5HT82_CAMJR
          Length = 341

 Score =  182 bits (462), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 46/235 (19%), Positives = 97/235 (41%), Gaps = 13/235 (5%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQR 63
           II+AGG G+RL  +T+   K +L +  KP++   +  L        +     + K   + 
Sbjct: 120 IIMAGGLGSRLKELTKDTPKPMLKVGKKPILESIVQRLKNQNFENFIFCVNYK-KQIIED 178

Query: 64  LLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHV 123
               G +FG+++ Y ++    G A A  + +       S LV+  +I     F+  L+  
Sbjct: 179 YFQKGQKFGVKISYIKERKKLGTAGALSLIKQEFK--ESFLVMNADILTELDFNDLLKAH 236

Query: 124 AARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEY 183
                  +V   +      +GV+         ++EEKP Q        G+Y  +++++  
Sbjct: 237 KKSKALMSVCVREFEQQIPYGVI-TQKQGFIENIEEKPTQ--KFLVSAGIYVLENEILNL 293

Query: 184 AKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
             + +  +  E     + ++ L+ G +   ++     W+D G  D  ++A+   +
Sbjct: 294 IAKNEYLDMPE-----LIKLVLQKGKVNTYIIND--YWIDIGRPDEFLKANEDFK 341


>UniRef50_A9B2A2 Nucleotidyl transferase n=1 Tax=Herpetosiphon aurantiacus ATCC
           23779 RepID=A9B2A2_HERA2
          Length = 326

 Score =  182 bits (462), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 60/240 (25%), Positives = 96/240 (40%), Gaps = 12/240 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +IL GG GTRL P+T  + K L+PI  + ++   L  L   G+R +++         
Sbjct: 1   MRAVILVGGLGTRLRPLTNQLPKPLVPIAGEALMSRTLRRLYKQGVRHVILAVQY-LAEQ 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGET---FLNGEPSCLVLGDNIFFGQGFS 117
           F    GDG+ FG+ L+  ++P   G A A          L   P  LVL  +       +
Sbjct: 60  FLAAYGDGAAFGLDLQIVQEPEALGTAGAVRYALDQTNLLKAGP-ILVLNGDELTDFDVA 118

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYF 175
              +        AT+   QV D   FGVV  D N R  + +EKP      +N   +G Y 
Sbjct: 119 QLWQAHGQFGGVATIAVRQVADTSAFGVVASDANQRVYAFQEKPAAGTALANTINSGAYV 178

Query: 176 YDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAST 235
           ++   +       P++   +    +    L    L        ++  D GT    + A+ 
Sbjct: 179 FEPAALAQI----PAQGFAMLERDLFPSLLATQALIYAYQHNAYS-QDIGTLAGYLAANE 233


>UniRef50_B7KYN3 Nucleotidyl transferase n=1 Tax=Methylobacterium chloromethanicum
           CM4 RepID=B7KYN3_METC4
          Length = 360

 Score =  182 bits (461), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 52/241 (21%), Positives = 93/241 (38%), Gaps = 12/241 (4%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQR 63
           +++AGG G RL P+T  + K L+ +  +P++   +      G     I          + 
Sbjct: 124 VLMAGGKGQRLLPLTEKLPKPLIQVAGRPILEIIIRRFAAQGFWRFAISVNF-LGHIIKE 182

Query: 64  LLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHV 123
             GDGS+ G+ + Y E+ S  G A +  +       + + LV   ++     +   L   
Sbjct: 183 HFGDGSQLGVSISYIEEGSSLGTAGSLGLLTE--TPDRAVLVSNGDLLTKLKYDWMLDFH 240

Query: 124 AARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEY 183
                 ATV   +      FGVV   D F    ++EKP      +   G+Y  +  V + 
Sbjct: 241 LQHGASATVAVREYDMQVPFGVVGTQDGF-VTQIDEKPVH--RFFISAGVYILEPSVFDL 297

Query: 184 AKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEKR 243
             + +      +++  + Q  +   +       R   WLD G HD L  A    +  E+ 
Sbjct: 298 VAKDER-----VDMPQVLQRLISRLDKVAAFPLRE-RWLDIGRHDDLERAEAEFEISEQD 351

Query: 244 Q 244
           +
Sbjct: 352 E 352


>UniRef50_B2VWC7 Mannose-1-phosphate guanyltransferase n=2 Tax=Leotiomyceta
           RepID=B2VWC7_PYRTR
          Length = 336

 Score =  182 bits (461), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 51/250 (20%), Positives = 92/250 (36%), Gaps = 36/250 (14%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK IIL GG GTRL P+T  + K L+   +KPMI + +  L  AG+ ++++         
Sbjct: 1   MKAIILVGGFGTRLRPLTLTLPKPLVEFANKPMIQHQIEALAAAGVTDVVLAVNYR---- 56

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                                 P+ +A+A        +  P   VL  ++     F    
Sbjct: 57  ----------------------PEIMAEALKANVLGKDDSPFF-VLNADVTCDYPFKQLA 93

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNF--RAISLEEKPKQPKSNWAVTGLYFYDS 178
               +  +  T+   +V +P ++GVV        +     EKP +   N    G+Y  ++
Sbjct: 94  EFHKSHGDEGTIVVTKVEEPSKYGVVVHKPGHASKIDRFVEKPVEFVGNRINAGIYIMNT 153

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
            V++  +    S   E     +    L + +L          W+D G     +  +    
Sbjct: 154 SVLKRIELRPTSIEQETFPAIVKDGLLHSFDL-------EGFWMDVGQPKDFLTGTCLYL 206

Query: 239 TVEKRQGFKI 248
           +   R+  K+
Sbjct: 207 SSLARKNSKL 216


>UniRef50_C4XP25 Nucleotidyl transferase domain protein n=3 Tax=Proteobacteria
           RepID=C4XP25_DESMR
          Length = 247

 Score =  181 bits (460), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 50/237 (21%), Positives = 88/237 (37%), Gaps = 12/237 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +ILAGG G+RL P T  + K L+PI   P++   +  L  AG   + +    + +   +
Sbjct: 5   AVILAGGLGSRLRPYTVVLPKPLMPIGPYPILEVVIRQLAAAGFTVVTLAVNHQAE-IIK 63

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
                G  +G+ + Y+ +  P G      + +   +     L++  ++     F     H
Sbjct: 64  AYCNSGQRWGVHINYSMEKKPLGTMGPLKLLDDLPDN---FLIMNGDVLTDLNFETFYAH 120

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
             +R    TV   Q      FGV++FD++       EKP          G+Y    K++E
Sbjct: 121 HTSRANAFTVATCQREVRSEFGVLDFDESDTLHGFREKP--VVHYHVSMGIYMASRKILE 178

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           +                   + + A    V +      WLD G  D  + A    + 
Sbjct: 179 FIPDDVA------YGFDNLVLDMMAAGKPVHVCRHNGYWLDIGRPDDYMTAIDMFEA 229


>UniRef50_B3T1I2 Putative Nucleotidyl transferase n=1 Tax=uncultured marine
           microorganism HF4000_010I05 RepID=B3T1I2_9ZZZZ
          Length = 295

 Score =  181 bits (459), Expect = 3e-44,   Method: Composition-based stats.
 Identities = 71/274 (25%), Positives = 122/274 (44%), Gaps = 33/274 (12%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY- 60
           K +I A G GTR  P+T+ V K+LLPI +KPM+ Y +     AGI++++I+ +P  +   
Sbjct: 13  KAVIPAAGLGTRFLPVTKAVPKELLPILEKPMLQYVVEEAAEAGIQQVIIVISPGKESIA 72

Query: 61  --------FQRLLGDGSEFGI-----------QLEYAEQPSPDGLAQAFIIGETFLNGEP 101
                    +R L D    G+            + +  Q +P GL  A +     +  EP
Sbjct: 73  AYFQPQPELERYLADSEAAGLLEKVGHATSLADVSFVIQENPLGLGHAVLTAREAVANEP 132

Query: 102 SCLVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQVMDPER---FGVVEF----DDNFRA 154
             ++L D+I              A+  GA V   + M  +R   +GVV+     +  ++ 
Sbjct: 133 FVVILPDDIIAHSPGVVSQMVAVAQRRGAGVVAVERMPWDRVQNYGVVDASQVEERVYQI 192

Query: 155 ISLEEK--PKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLT- 211
             + EK  P++  SN  V G Y    ++ +  ++  P  +GE+++T    + L++  L  
Sbjct: 193 RGMVEKPPPEEAPSNLTVVGRYILPPEIFDCLERTLPGAKGEIQLTDGLTILLDSQKLYA 252

Query: 212 VELLGRGFAWLDTGTHDSLIEASTFVQTVEKRQG 245
            E LGR +   D GT   L++AS       +   
Sbjct: 253 YEFLGRRY---DGGTPLGLLQASLEFALAREDTR 283


>UniRef50_C2G0W6 Nucleotidyl transferase n=1 Tax=Sphingobacterium spiritivorum ATCC
           33300 RepID=C2G0W6_9SPHI
          Length = 350

 Score =  180 bits (458), Expect = 3e-44,   Method: Composition-based stats.
 Identities = 51/239 (21%), Positives = 97/239 (40%), Gaps = 11/239 (4%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            I++AGG G RL P+T    K LL + DKP+I Y +  L   G+  I +      +   +
Sbjct: 122 AILMAGGEGRRLRPLTENTPKPLLRVGDKPIIEYNIDRLKEVGVSTINLSINYLGEQLVE 181

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
              GDGS+  I ++Y  +  P G     ++ + F       +V+  ++     F    + 
Sbjct: 182 -YFGDGSKKEINIKYVREDKPLGTIGGILLVDHF--NHDDIIVMNSDLLTNIDFGDFFKT 238

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
                    V          + V+E ++     SL+EKP+   + ++  G+Y     ++ 
Sbjct: 239 FKDTNADMAVAATSYHVDVPYAVLEVNETNTVRSLKEKPRY--TYYSNAGIYILKKDLLR 296

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVE 241
              + +        IT +    +E     +     G+ WLD G H+   +A   ++ ++
Sbjct: 297 MIPKDEF-----FNITDLMDRVIEMNLKLITYPINGY-WLDIGKHEDFKKAQEDIKHIK 349


>UniRef50_D1PXL9 Mannose-1-phosphate guanyltransferase n=2 Tax=Bacteroidales
           RepID=D1PXL9_9BACT
          Length = 416

 Score =  180 bits (458), Expect = 4e-44,   Method: Composition-based stats.
 Identities = 45/241 (18%), Positives = 89/241 (36%), Gaps = 11/241 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +I+AGG GTR+  +   + K ++P+  KP+I + + +    G  E + +        
Sbjct: 1   MKVVIIAGGQGTRIASLNSEIPKAMIPVCGKPVIEHQVEMAKRYGFTEFIFLIGY-LGEQ 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   G+GS + + ++Y  + +P G A A       L+ +    V   +           
Sbjct: 60  VESYFGNGSHWDVHIDYYHETTPLGTAGAIAEVRDKLSDD--FFVFYGDTVMDVDMRRME 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP---KQPKSNWAVTGLYFYD 177
                    AT+F +    P    +V  D + R +S+  KP        N     L+ + 
Sbjct: 118 TFHKEHRADATLFVHPNDHPYDSDIVILDKDHRVMSIATKPHADDFVSHNIVNAALFIFS 177

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
             +V+  ++   +        ++    ++ G      L   +   D GT +    A    
Sbjct: 178 KNIVDCIEKGTKT----HIEKNVLPECIKRGMKLYGYLSSEYV-KDMGTPERYEAACKAW 232

Query: 238 Q 238
            
Sbjct: 233 A 233


>UniRef50_Q036S8 Glucose-1-phosphate adenylyltransferase n=9 Tax=Lactobacillus
           RepID=GLGC_LACC3
          Length = 380

 Score =  180 bits (458), Expect = 4e-44,   Method: Composition-based stats.
 Identities = 67/258 (25%), Positives = 110/258 (42%), Gaps = 21/258 (8%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDK-PMIYYPLSVLMLAGIREILIITTPEDKG 59
           M G+ILAGG GTRL  +T+  +K  +P   +  +I + LS L  +G+    +IT  +   
Sbjct: 5   MLGMILAGGQGTRLGKLTKTTAKPSVPFGGRYRIIDFTLSNLANSGVNTAGVITQYQPLE 64

Query: 60  YFQRLLGDGSEFGIQ------------LEYAEQPSPDGLAQAFIIGETFLNGEPS--CLV 105
              R + +G+ +G+                  +   +G A A      +++       L+
Sbjct: 65  -LNRHIQNGASWGLNERGAGVTILQPYASSEGEKFFEGTAHAIYQNIAYIDSYNPQYLLI 123

Query: 106 LGDNIFFGQGFSPKLRHVAARTEGATVFGYQVMDPE--RFGVVEFDDNFRAISLEEKPKQ 163
           L  +  +   +   L +  A+    TV    V   E  RFG++  DD  R I  EEKP +
Sbjct: 124 LSGDHIYKMDYQAMLDYHKAKKASLTVAVMPVEKEEAKRFGIMNTDDTDRIIEFEEKPAK 183

Query: 164 PKSNWAVTGLYFYD-SKVVEYAKQVKPSERG-ELEITSINQMYLEAGNLTVELLGRGFAW 221
           PKSN A  G+Y ++   + +Y  +   ++   E     +   YL     +     RG+ W
Sbjct: 184 PKSNLASMGIYIFNWPTLKQYLTESYATDGAMEDFGHDVIPAYLTHNEASYAYAFRGY-W 242

Query: 222 LDTGTHDSLIEASTFVQT 239
            D GT  SL EA+     
Sbjct: 243 KDVGTIQSLWEANMEFLN 260


>UniRef50_Q31FM5 Nucleotidyl transferase n=1 Tax=Thiomicrospira crunogena XCL-2
           RepID=Q31FM5_THICR
          Length = 361

 Score =  180 bits (458), Expect = 4e-44,   Method: Composition-based stats.
 Identities = 48/242 (19%), Positives = 90/242 (37%), Gaps = 12/242 (4%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQR 63
           +++ GG GTRL P+T  + K +L + DKP++   ++ +   G                + 
Sbjct: 123 VLMLGGLGTRLRPLTESIPKPMLRVGDKPILETIVTHIAEQGFVNFYFCINY-LGEQIRS 181

Query: 64  LLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHV 123
             GDGS++GI +EY E+    G A A  +       E   +V+  ++      S  L   
Sbjct: 182 YFGDGSQWGIHIEYVEEEERRGTAGALSLLPE--KPELPFIVMNGDLLTKVNLSSLLDFH 239

Query: 124 AARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEY 183
                 AT    +      +GVVE  +    I + EKP      +   G+Y    + +E 
Sbjct: 240 EEHHNIATACVREYAQQVPYGVVEI-EGAHVIQMVEKP--VYRYFVNAGIYALSPEAMEK 296

Query: 184 AKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEKR 243
             +         ++ ++    L             + W+D G      +A    +   ++
Sbjct: 297 VPEQAF-----YDMPTLIDEVLAEKGNVGGFPITEY-WMDIGQMPDFEQAQADYEVHFQK 350

Query: 244 QG 245
           + 
Sbjct: 351 RN 352


>UniRef50_C6VS96 Nucleotidyl transferase n=1 Tax=Dyadobacter fermentans DSM 18053
           RepID=C6VS96_DYAFD
          Length = 243

 Score =  180 bits (457), Expect = 4e-44,   Method: Composition-based stats.
 Identities = 58/235 (24%), Positives = 97/235 (41%), Gaps = 10/235 (4%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQR 63
           +I+AGG GTRL P+T    K L+P+  KP+I + +  L   G+REI I      +   + 
Sbjct: 15  VIMAGGKGTRLKPLTDNTHKSLIPVGGKPIIRHLIDHLASFGLREIHISVGHLAEQVIE- 73

Query: 64  LLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHV 123
            LGDG E G+ L Y ++  P G   A  + + +       LV+  +++            
Sbjct: 74  YLGDGCEPGVTLRYVKERIPMGSIGALTLKQRW--PHEHFLVINGDVYANFDVHHFCSTY 131

Query: 124 AARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEY 183
            AR     V          +GV+E + N       EKP+         G+Y ++ KV+  
Sbjct: 132 FARQADMAVLAVPNTVKVPYGVLEINQNGDISHFSEKPEYDL--MVNAGVYIFNQKVLNL 189

Query: 184 AKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
             +    E        + +  + AG     +      W+D G+ ++L +A    Q
Sbjct: 190 LPKRIAYEG-----WQLIESAMHAGLHVAGVPQDSGYWIDIGSMETLQKAQEMSQ 239


>UniRef50_Q0W805 Putative glucose-1-phosphate thymidylyltransferase n=2
           Tax=Euryarchaeota RepID=Q0W805_UNCMA
          Length = 332

 Score =  180 bits (457), Expect = 5e-44,   Method: Composition-based stats.
 Identities = 59/253 (23%), Positives = 111/253 (43%), Gaps = 9/253 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +I A G+G RL+P T    K ++ +  KP+I + L   +     E++I+     +  
Sbjct: 1   MKVVIPAAGAGKRLYPHTYTKPKPMVYVAGKPIIGHILDKAVDLQPDELIIVVGYMKEKL 60

Query: 61  FQRLLGDGSEFGI--QLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSP 118
              +  D    GI  ++ Y  Q    GL  +  +    ++  P  + LGD IF G     
Sbjct: 61  IDYV--DEHYCGIFKKITYVHQDQQLGLGHSIYVAREAIDDAPIMIALGDMIFKGGYSDF 118

Query: 119 KLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYD- 177
              H        ++   ++ +P  +G+V  + +     + EKPK+  S   + G+YF D 
Sbjct: 119 ARLHACNGKCSGSIGVKEIDNPSHYGIVFLNGDGTIKKMVEKPKKSSSRLGIAGVYFIDD 178

Query: 178 -SKVVEYAKQVKPSER-GELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAST 235
              ++   ++V  +   GE+++T   Q  +EAG  +        +W D G  +SL+E + 
Sbjct: 179 TPGLIRALEKVVENRGEGEVQLTDALQKAIEAG--SDYKPFEVSSWYDCGRPESLLEVNR 236

Query: 236 FVQTVEKRQGFKI 248
            +   + +  +K 
Sbjct: 237 LLLAEKSKMSWKP 249


>UniRef50_D2RP80 Nucleotidyl transferase n=2 Tax=Haloterrigena turkmenica DSM 5511
           RepID=D2RP80_9EURY
          Length = 392

 Score =  180 bits (456), Expect = 6e-44,   Method: Composition-based stats.
 Identities = 55/234 (23%), Positives = 96/234 (41%), Gaps = 6/234 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M  ++LAGG G+RL P+T+   K LLP    P++ +    L+ AG+ EI ++     +  
Sbjct: 1   MSAVVLAGGEGSRLRPLTKHRPKPLLPAATTPILEHVFDQLLEAGVTEITVVVGYR-RNR 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            Q   G      + L Y  Q    G   A +  E+ ++G  + +V GD I      S  L
Sbjct: 60  VQAHFGSTYR-NVPLTYVTQDQQLGSGHALLTAESTVDG-TTIVVNGDQIVESTVISDVL 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                 +  AT+     +D   +G V  DD      + E P+  ++     G+Y ++  +
Sbjct: 118 EAHDDNSAVATLGLLNRVDVSSYGGVILDD-GEVTEIVENPQDERTYRFNAGVYAFEPAI 176

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
            +  +  +P   GE  +       L +       +  G  W+D      L++ S
Sbjct: 177 FDAVRAAEPRA-GEQSLIDAINELLASDEAVRGTVSEGL-WVDATYPWDLLDVS 228


>UniRef50_Q5UXR9 Glucose-1-phosphate thymidylyltransferase n=2 Tax=Halobacteriaceae
           RepID=Q5UXR9_HALMA
          Length = 396

 Score =  180 bits (456), Expect = 7e-44,   Method: Composition-based stats.
 Identities = 58/254 (22%), Positives = 108/254 (42%), Gaps = 11/254 (4%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            ++LA G GTRL P+TR   K +LP  ++P++ +    L+ AGI +++++   + +   Q
Sbjct: 6   AVVLAAGEGTRLRPLTRNRPKPMLPAANRPILEHVFDALVEAGIEKLVVVVGYK-RDRVQ 64

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
              G     G+ + Y  Q    G   A +   + ++G    LV+  +         ++  
Sbjct: 65  DHFGPTYR-GVPISYVSQTKQLGSGHALLQARSVVDG--PVLVMNGDRLVDAATIEEVDT 121

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
             A T   ++   +  D  R+G VE  D    + + EKP+  +      G+Y +D  + E
Sbjct: 122 SYAETGNTSIAVLERQDTSRYGAVEVQDRD-IVDIVEKPQHDEFRLINGGVYAFDGDIFE 180

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEK 242
              +      GEL +T   ++ LE+    V+ +     W+D      L+   T  + V  
Sbjct: 181 AIDETTRHA-GELALTDTIELLLESDR--VQAVEVDGMWVDATYPWDLL---TVAREVLA 234

Query: 243 RQGFKIACLEEIAW 256
           R     +  +E  W
Sbjct: 235 RGRVVESARDEQVW 248


>UniRef50_A1VGN4 Nucleotidyl transferase n=1 Tax=Desulfovibrio vulgaris DP4
           RepID=A1VGN4_DESVV
          Length = 367

 Score =  179 bits (455), Expect = 8e-44,   Method: Composition-based stats.
 Identities = 51/238 (21%), Positives = 93/238 (39%), Gaps = 16/238 (6%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +I+ GG G+RL  +T    K +L +  KP++   +  ++ AGI      T    K   +
Sbjct: 125 AVIMCGGLGSRLGHLTHNCPKPMLEVGGKPILERIMCSIIQAGISRFFFAT-HYLKEKIE 183

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
              G+G ++G+Q+EY ++    G   A  +   ++   P  L++  +I         L  
Sbjct: 184 CYFGNGEKWGVQIEYLKEKKRMGTGGALSL-MPYVPSHP-MLIMNGDILTEFNIRHLLDF 241

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
            +     AT+   +      +GVV  +     + ++EKP    S +   G+Y  +  +VE
Sbjct: 242 HSMTNSIATMAIAEYCYQNPYGVVRHEGTM-LLDIDEKPTN--SWFINAGIYVAEPSLVE 298

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNL--TVELLGRGFAWLDTGTHDSLIEASTFVQ 238
              Q             +  + L A     T+ +      WLD G       A   +Q
Sbjct: 299 KVPQDT--------FIDMPTLLLNAKKKGETISIFPICEKWLDIGREPDYRSAQRMIQ 348


>UniRef50_C4PX01 Gdp-mannose pyrophosphorylase b, isoform 2 n=1 Tax=Schistosoma
           mansoni RepID=C4PX01_SCHMA
          Length = 413

 Score =  179 bits (455), Expect = 8e-44,   Method: Composition-based stats.
 Identities = 54/234 (23%), Positives = 90/234 (38%), Gaps = 13/234 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +IL GG GTRL P+T  + K L+   +KPM+ + +  L+   I EI++    E +  
Sbjct: 54  MKALILIGGYGTRLRPLTLSIPKPLVEFANKPMLLHQIKALLEVDITEIILAINREAEVL 113

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGL---AQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
              +     + G+         P  L            FL GE    VL  +I     F 
Sbjct: 114 ESSIRESCDKVGVN-HCNVFFVPYILVTVGGPLAQAAPFLTGERFF-VLNSDIICNYPFK 171

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFG-VVEFDDNFRAISLEEKPKQPKSNWAVTGLYFY 176
             L    +  +  T+   +V +P ++G VV  D         EKP +  +N    GLY +
Sbjct: 172 RMLEFHLSHGKEGTMAVTKVEEPSKYGAVVHNDQTGLVKRFVEKPSEYVANRINAGLYIF 231

Query: 177 DSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSL 230
           +  +++  +    S       T++    +    L    +     W+D G     
Sbjct: 232 EPTILKRIEAKPMSIE-----TAVFPAMVRDSEL--YCIEFSGFWMDIGQPADY 278


>UniRef50_B3PKU9 Nucleotidyltransferase family protein n=1 Tax=Cellvibrio japonicus
           Ueda107 RepID=B3PKU9_CELJU
          Length = 234

 Score =  178 bits (453), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 52/239 (21%), Positives = 99/239 (41%), Gaps = 10/239 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +ILA G G R+ P+T  + K +LP+  KP++ Y L  L  AGI +++I         
Sbjct: 1   MKAMILAAGLGQRMRPLTNHLPKPMLPLGGKPLLDYHLEKLPAAGITQVIINLAY-LGDK 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  +GDG  +G+++ Y+E+P P     A +     L   P  L+   +++         
Sbjct: 60  IRAYVGDGQRYGLEVIYSEEPEPLETGGALLKALPLLGESPFLLI-NGDVWCDLDLRQFS 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           +H    T+   +    + +P+     +F    +   L +  +Q    +   G+     + 
Sbjct: 119 QHRLRETQMGHLLL--IPNPDFHPRGDFALGAQQYLLPDPQQQHPWRYTFAGISLLRPE- 175

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
                   P  R +  +  + +  ++ G L+ E+      W D GT + L      +Q 
Sbjct: 176 ---LIATYPHRRHKFPLVEVLRHAIDRGQLSAEV--HTGQWSDIGTPERLHALEQQLQA 229


>UniRef50_A8RPP5 Putative uncharacterized protein n=2 Tax=Clostridium
           RepID=A8RPP5_9CLOT
          Length = 235

 Score =  178 bits (453), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 51/232 (21%), Positives = 93/232 (40%), Gaps = 8/232 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ I+LAGG GTRL  +     K +  I  KP + Y    L+  GI +I+     +    
Sbjct: 1   MQAILLAGGLGTRLRSVVSDRPKPMALIEGKPFMEYVTRELVRHGITDIVFAVGYK-GTM 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDG+ FG    YA + +  G A A      F+  +    VL  + F+   ++  L
Sbjct: 60  VEEHFGDGAAFGFHAGYAYEETLLGTAGAIKNAGRFITEDRFY-VLNADTFYQIDYTRLL 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           R   ++     +   +V D  R+G    D +       EK +  +      G+Y    ++
Sbjct: 119 RQQDSQNLDMALVLRRVPDVSRYGQAILDRDGFLTGFNEKTEDAREGTINGGIYLMKQQL 178

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIE 232
           ++   + K S         +   +L  G      +  G+ ++D G  ++  +
Sbjct: 179 LDEIPEGKVSLEN-----DMIPKWLSEGRRLGGFVNDGY-FIDIGIPEAYFQ 224


>UniRef50_P37820 Putative mannose-1-phosphate guanyltransferase n=12
           Tax=Sulfolobaceae RepID=MPG1_SULAC
          Length = 359

 Score =  178 bits (453), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 57/244 (23%), Positives = 98/244 (40%), Gaps = 11/244 (4%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            I+LAGG  TRL P++    K LLP+  KP++ Y L  L  + +  I +           
Sbjct: 4   AIVLAGGYATRLRPLSLTKPKALLPVLGKPLMDYTLYSLASSDVDTIYLSLRVMADKVLD 63

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
            +          +    + S  G A       +  N     +V+  +I+    F+  L +
Sbjct: 64  HVKQLN--LQKNIVSVIEESRLGDAGPLKFINSKYNLSDDVIVVYGDIYAEIDFNKLLEY 121

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
             ++   AT+   QV DP R+GV+  D + R I + EKPK P SN    G+Y +  +++ 
Sbjct: 122 HQSKGCNATLTATQVEDPSRYGVLITDGH-RLIQIIEKPKTPLSNLVNAGIYVFKKELLN 180

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEK 242
               +  S              L   +  V +      W+D G     +  +  + T++ 
Sbjct: 181 KIDGLSIS-------RDFLPKLL-VSDTCVSVYPYKGLWMDIGVPRDYMRINLELLTLKY 232

Query: 243 RQGF 246
            +GF
Sbjct: 233 PKGF 236


>UniRef50_A4WLA7 Nucleotidyl transferase n=6 Tax=Thermoproteaceae RepID=A4WLA7_PYRAR
          Length = 360

 Score =  178 bits (453), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 56/237 (23%), Positives = 99/237 (41%), Gaps = 16/237 (6%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREIL--IITTPEDKGY 60
           GIILAGG  TRL P++    K L P+  KP+I + +       + E+   +I+       
Sbjct: 5   GIILAGGFATRLRPLSYTKPKPLFPVLGKPVIDWIIEK-----VVEVAEPVISARYLSSM 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  +   S++G ++   E+  P G   A +     L  + +  V   ++F         
Sbjct: 60  IRSHVA--SKWGGRVRIVEEDRPLGDGGAVVNVVKSLGVKGAITVANGDVFTDISIKDVW 117

Query: 121 RHVAARTEGATVFGYQVMD--PERFGVVEFDDNFRAISLEEKPKQPK-SNWAVTGLYFYD 177
                +    T+   +V      RFG+   +D+ R     EKPK+P  SN A  G+Y ++
Sbjct: 118 EFHKRKGAAVTIALVEVPPEEVSRFGIALLEDDGRIARFVEKPKEPVGSNLANAGVYIFE 177

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
            + V  A+  +P+         I    +E  ++   +      W D GTH   ++A+
Sbjct: 178 PEAV--AEFPEPNAGELKIARHIIPRLMEKFDIYGYV--HKGLWFDIGTHIDYLKAN 230


>UniRef50_A8MC98 Nucleotidyl transferase n=1 Tax=Caldivirga maquilingensis IC-167
           RepID=A8MC98_CALMQ
          Length = 364

 Score =  178 bits (453), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 53/236 (22%), Positives = 94/236 (39%), Gaps = 7/236 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +  IILAGG  TRL P+T    K LLPI +K +I + L  +      ++ +      +  
Sbjct: 2   VDVIILAGGYATRLRPLTFTKPKPLLPILNKAVIDWILESVTKVKPSDVFLSVRYMSELI 61

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            + +    +     +   ++  P G         +    +   +V   +IF        +
Sbjct: 62  EKHVNHRWASLRDIVNIIKEDKPLGDGGPVSYIASMRELDDIVVVFNGDIFTKIDLEDAI 121

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
               ++   AT+   QV D  ++GVV    +       EKP+  +  SN    G+Y +  
Sbjct: 122 NEHVSKGALATICLTQVNDVSQYGVVTLGRDNLVTGFVEKPEPGKAPSNLINAGVYIFSK 181

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
             ++Y    KP   G+L I  I    ++   +   +L     W D GT  S ++A+
Sbjct: 182 DALKYFP--KPGTFGKLAI-DILPKMIKDHKVYGYILK--GYWYDIGTITSYLDAN 232


>UniRef50_Q67RD1 Glucose-1-phosphate thymidylyltransferase n=1 Tax=Symbiobacterium
           thermophilum RepID=Q67RD1_SYMTH
          Length = 364

 Score =  178 bits (453), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 66/223 (29%), Positives = 102/223 (45%), Gaps = 6/223 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           ++ ++L    GTRL P+T   +K  LP+  +P+  +  S L   G  EI ++  P  +  
Sbjct: 10  VRALVLCASRGTRLRPLTHTWAKASLPVAGRPIWQHIFSYLAAHGFDEIGVVVGPGQEEL 69

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            + +     +   ++    Q  P G+A A      FL  +P  L LGDN        P L
Sbjct: 70  ARSVKRWSPQ---RVTVILQAEPAGIAHAVAAARPFLADQPFLLYLGDN-LTNADLGPAL 125

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           R   A    A +   +V DP  FGV   D   R  ++ EKP +P S+ A+ G+YF+  +V
Sbjct: 126 RRFRAEAPSALITLQRVADPRTFGVAVLDG-GRVTAVAEKPAEPTSDLAIAGIYFFSPEV 184

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLD 223
                 + PS RGELEIT      +  G + +     G+ W+D
Sbjct: 185 HAAIAGLTPSARGELEITDAIARLIAGGRIVLGHELSGW-WVD 226


>UniRef50_C5ELG1 HAD-superfamily protein n=2 Tax=Clostridiales RepID=C5ELG1_9FIRM
          Length = 261

 Score =  178 bits (452), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 49/232 (21%), Positives = 91/232 (39%), Gaps = 8/232 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ I+LAGG GTRL  +     K +  I  +P + Y    L+ +G+ +I+     +    
Sbjct: 27  MQAILLAGGLGTRLRSVVSDRPKPMALIEGRPFMEYVTRELVRSGMTDIIFAVGYK-GTM 85

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDG  FG    YA + +  G A A      F+  E    VL  + F+   ++   
Sbjct: 86  VEEYFGDGERFGFHASYAYEETLLGTAGAIKNAGRFVTEERFF-VLNADTFYQIDYTRLK 144

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           R   +      +   +V D  R+G    D      +  EK ++ +      G+Y     +
Sbjct: 145 RLQDSLDLDMALVLREVPDVSRYGQAILDGKGFLTAFNEKTEETRMGTINGGIYLMRRSL 204

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIE 232
           ++   + K S         +   +L  G      +  G+ ++D G  ++  +
Sbjct: 205 MDTIPEGKVSLEN-----DMIPKWLREGKGLGGFVNDGY-FIDIGIPEAYRQ 250


>UniRef50_Q54800 UTP--glucose-1-phosphate uridylyltransferase n=15 Tax=Bacteria
           RepID=CAP3C_STRPN
          Length = 306

 Score =  178 bits (452), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 57/271 (21%), Positives = 109/271 (40%), Gaps = 37/271 (13%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K +I A G GTR  P T+ ++K++LPI D+P I++ +   + +GI +IL++T    +   
Sbjct: 6   KAVIPAAGLGTRFLPATKALAKEMLPIVDRPTIHFVIEEALRSGIEDILVVTGKSKRS-I 64

Query: 62  QRLLGDGSEF--------------------GIQLEYAEQPSPDGLAQAFIIGETFLNGEP 101
           +       E                      I++ +  Q SP GL  A +  ++F+  +P
Sbjct: 65  EDYFDSTFELEYSLRKQGKMELLKSVNESTDIKVHFVRQSSPRGLGDAVLQAKSFVGDDP 124

Query: 102 SCLVLGDNIF-----FGQGFSPKLRHVAARTEGATVFGYQV--MDPERFGVVEF-----D 149
             ++LGD++           + +L      T+ +T+    V   D   +GV+       +
Sbjct: 125 FVVMLGDDLMDITDSTAVPLTRQLMDDYNATQASTIAVMPVRYEDVSSYGVISPRLESSN 184

Query: 150 DNFRAISLEE--KPKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEA 207
             +   +  E  KP++  SN A+ G Y    ++    +  KP    E+++T         
Sbjct: 185 GLYSVDAFVEKPKPEEAPSNLAIIGRYLLTPEIFSILETQKPGAGNEIQLTDAIDTL--N 242

Query: 208 GNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
              +V          D G   + ++ S    
Sbjct: 243 KTQSVFAREFVGKRYDVGDKFNFMKTSIDYA 273


>UniRef50_A4BEN1 Nucleoside-diphosphate-sugar pyrophosphorylase n=3
           Tax=Proteobacteria RepID=A4BEN1_9GAMM
          Length = 359

 Score =  178 bits (451), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 50/240 (20%), Positives = 89/240 (37%), Gaps = 11/240 (4%)

Query: 5   ILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQRL 64
           ++AGG G RL P+T    K +L + DKP++   L   + AG     I T        +  
Sbjct: 124 LMAGGFGKRLRPLTNNCPKPMLKVGDKPILETILEQFIDAGFHNFFIST-HYLNEQIEAY 182

Query: 65  LGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHVA 124
            GDG+ +G+ + Y  + +P G A A  +        P  L++  ++     F   L +  
Sbjct: 183 FGDGANYGVSISYINEQTPLGTAGAIGLLPESAKQLP-FLMMNGDLLTRVNFDELLEYHM 241

Query: 125 ARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEYA 184
                 +V   +      FGVV+   +     + EKP Q    +   G+Y          
Sbjct: 242 REGSDVSVAVREYQMQVPFGVVQHQGSV-ISDIVEKPVQN--YFINAGIYCISPSAAFAV 298

Query: 185 KQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEKRQ 244
             +       L++  + +  ++ G          + WLD G      +A     +   R+
Sbjct: 299 DGINV-----LDMPDLIESRIKLGRKVSMFPIHEY-WLDIGQLPDFEQAQIDYSSRFSRR 352


>UniRef50_A9VB22 Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9VB22_MONBE
          Length = 342

 Score =  178 bits (451), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 52/233 (22%), Positives = 89/233 (38%), Gaps = 29/233 (12%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +IL GG GTRL P+T  + K L+P  + PM+ + +  L+ AG+  +++      +  
Sbjct: 1   MKALILVGGFGTRLRPLTLSLPKPLVPFANLPMVMHQVEALVKAGVDHVVLAVNYRAE-- 58

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                              Q        A  + E+ L       VL  ++     F   +
Sbjct: 59  -----------------IMQDEIK--KHAERLAESILRDGEPFFVLNSDVICQFPFKELV 99

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDN-FRAISLEEKPKQPKSNWAVTGLYFYDSK 179
               A  +  T+   +V +P ++GVV  D +        EKPK    N    GLY ++ +
Sbjct: 100 AFHKAHGKEGTILVTKVEEPSKYGVVVSDKDTGCIERFVEKPKIFVGNRINAGLYIFNPE 159

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIE 232
           +++  +    S   E     I     E  NL    +     W+D G     ++
Sbjct: 160 ILDRIEPRPTSIEKE-----IFPAMAETQNL--YAMDLPGFWMDVGQPPDYLK 205


>UniRef50_C6X012 Glucose-1-phosphate thymidylyltransferase n=17 Tax=Bacteroidetes
           RepID=C6X012_FLAB3
          Length = 339

 Score =  178 bits (451), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 65/251 (25%), Positives = 103/251 (41%), Gaps = 18/251 (7%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLML-AG--IREILIITTPED 57
           MK I+   G G+RL P T  V K L+PI  KP++   +  +   AG  I EI  I     
Sbjct: 1   MKIIVPMAGRGSRLRPHTLTVPKPLIPIAGKPIVQRLVEDIAKVAGEKIDEIAFIIGDFG 60

Query: 58  KGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
                 L+      G +     Q  P G A A    E  + G+   +V   +  F   F 
Sbjct: 61  SEVEASLIQIAESLGAKGTVYTQDEPLGTAHAIKCAENSMQGD--VVVAFADTLFKADF- 117

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYD 177
                +  +     ++  +V DP  FGVV+ DD        EKP    S+ A+ G+Y+++
Sbjct: 118 -----ILDKNSDGVIWVKKVDDPSAFGVVKLDDYGFITDFVEKPATFVSDLAIIGIYYFN 172

Query: 178 S-----KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIE 232
           S       + Y       + GE ++T+  +   + G      LG+   W+D G  ++ +E
Sbjct: 173 SAEKLMDEINYIMSNDIKQGGEYQLTTALENLRQKGAKFS--LGKVDDWMDCGNKNATVE 230

Query: 233 ASTFVQTVEKR 243
            +  V   EK 
Sbjct: 231 TNGKVLNYEKD 241


>UniRef50_A7GGU6 Nucleotidyl transferase family protein n=4 Tax=Clostridium
           botulinum RepID=A7GGU6_CLOBL
          Length = 358

 Score =  178 bits (451), Expect = 3e-43,   Method: Composition-based stats.
 Identities = 53/238 (22%), Positives = 104/238 (43%), Gaps = 12/238 (5%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQR 63
           II+AGG GTRL  +T+ + K +L I + P++ + ++     G  +  I    + +   + 
Sbjct: 124 IIMAGGLGTRLKDLTKEIPKPMLRIGNDPILQHIINNFKQYGYNKFFISVNYKAE-IIEN 182

Query: 64  LLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHV 123
              DG  +G+++EY ++    G A    + E+F+N      V+  +IF        + + 
Sbjct: 183 YFQDGYIYGVKIEYIKEQKRMGTAGGIKLAESFVNK--PFFVINGDIFTNLNLENMMTYH 240

Query: 124 AARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEY 183
              +   TV   +      +GVV+ ++N   I ++EKP          G+Y  + KV+  
Sbjct: 241 IDNSFDITVGTRKHSFQIPYGVVKTEEN-SIIGMKEKPNME--YLINAGVYCLNPKVINL 297

Query: 184 AKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVE 241
             Q +       EIT +  + ++ G L V        W+D G  +   + +  +  ++
Sbjct: 298 IPQDEY-----FEITDLIGICIKNG-LKVGCYEIKEYWMDIGRIEDYNQVNEDIYNLD 349


>UniRef50_Q01PZ9 UDP-glucose pyrophosphorylase n=1 Tax=Candidatus Solibacter
           usitatus Ellin6076 RepID=Q01PZ9_SOLUE
          Length = 308

 Score =  178 bits (451), Expect = 3e-43,   Method: Composition-based stats.
 Identities = 73/276 (26%), Positives = 114/276 (41%), Gaps = 33/276 (11%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTP------- 55
            ++   G GTRL P T+   K++LP+  KP++ Y +  L+  GI +IL +T         
Sbjct: 15  AVVPVAGLGTRLLPATKSQPKEMLPVARKPIVQYVVEELVSNGIEQILFVTGRSKASIEN 74

Query: 56  ---EDKGYFQRLLG----------DGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPS 102
               D   FQ L            D      +  Y  Q    GL  A +  E F   EP 
Sbjct: 75  HFDHDPELFQALTQANKQDLLSELDVVALKAKFFYTRQRMQRGLGDAIMCAENFAGEEPF 134

Query: 103 CLVLGDNIFFGQGFSPKLRHVA----ARTEGATVFGYQVMDPE--RFGVVE----FDDNF 152
            + LGD+I      S  +  +A    ++     +   +V   E   +G+V+     DD F
Sbjct: 135 LVALGDSILGLNAVSKAVARMADVFDSKRASCVIAVEEVPAEETRHYGIVQPEAGADDVF 194

Query: 153 RAISLEEK--PKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNL 210
           R ++L EK  PK   SN A+ G Y +   + +  ++VKP +RGE+++T   Q   E G  
Sbjct: 195 RVVNLVEKPAPKDAPSNLAIAGRYIFSPVLFDMIRRVKPDKRGEIQLTDAIQFMCEEGRR 254

Query: 211 TVEL-LGRGFAWLDTGTHDSLIEASTFVQTVEKRQG 245
            + + L       D G   S  E+       +   G
Sbjct: 255 VMAVKLTPEEKRYDIGNFPSYFESFVEFALADPIYG 290


>UniRef50_A6TK87 UTP-glucose-1-phosphate uridylyltransferase n=5 Tax=Bacteria
           RepID=A6TK87_ALKMQ
          Length = 307

 Score =  177 bits (450), Expect = 3e-43,   Method: Composition-based stats.
 Identities = 66/303 (21%), Positives = 117/303 (38%), Gaps = 35/303 (11%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K +I A G GTR  P T+ + K++LPI DKP + Y +   + +GI EILIIT        
Sbjct: 5   KAVIPAAGLGTRFLPATKALPKEMLPIVDKPTLQYIIEEAVDSGIEEILIITGRNKSS-I 63

Query: 62  QRLLGDGSEFG---------------------IQLEYAEQPSPDGLAQAFIIGETFLNGE 100
           +       E                       + + Y  Q  P GL  A    ++F+  E
Sbjct: 64  ENHFDKSIELELELEKKGKDELLKQVRAISDMVNIHYIRQKEPKGLGHAIHCAKSFIGNE 123

Query: 101 PSCLVLGDNIFF-GQGFSPKLRHVAARTEGATVFGYQVMDPE--RFGVVEF----DDNFR 153
           P  ++LGD+I    +    ++  +    +   +   +V      ++G+V+        ++
Sbjct: 124 PFAVMLGDDIVENDKPCLEQMMEMYDEYKTTILGVQEVPKESVNKYGIVDGMHIEGGIYK 183

Query: 154 AISLEEK--PKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLT 211
              L EK  P++  SN A+ G Y  + ++ +  +  KP + GE+++T   +    A    
Sbjct: 184 VKDLVEKPSPQEAPSNIAILGRYIINPEIFDILENTKPGKGGEIQLTDALKEL--AHREA 241

Query: 212 VELLGRGFAWLDTGTHDSLIEASTFVQTVEK--RQGFKIACLEEIAWRNGWLDDEGVKRA 269
           +          D G     +EA+       +  R+GF     + +         E V   
Sbjct: 242 MYAYVFEGRRHDVGDKQGFLEATVEFALKREDLREGFLNYLEDVVKKERESKALEEVAVT 301

Query: 270 ASS 272
              
Sbjct: 302 TEQ 304


>UniRef50_Q7X521 PtmE n=1 Tax=Campylobacter coli RepID=Q7X521_CAMCO
          Length = 220

 Score =  177 bits (450), Expect = 3e-43,   Method: Composition-based stats.
 Identities = 47/233 (20%), Positives = 98/233 (42%), Gaps = 13/233 (5%)

Query: 6   LAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQRLL 65
           +AGG GTRL  +T+   K +L +  KP++   +  L        +     + K   +   
Sbjct: 1   MAGGLGTRLKELTKDTPKPMLKVGKKPILESIVQKLKEQNFENFIFCVNYK-KQIIEDYF 59

Query: 66  GDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHVAA 125
             G  FG+++ Y ++    G A A  + +   + + S +V+  +I     F+  L+    
Sbjct: 60  KKGKNFGVKIFYIKERKKLGTAGALSLIKQ--DFKESFIVMNADILTELNFNELLKAHKD 117

Query: 126 RTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEYAK 185
                +V   +      FGV+E +  F   ++ EKP Q        G+Y  + +++E   
Sbjct: 118 SKALMSVCVREFEQQIPFGVIEQNKGF-ITNITEKPVQ--KFLVSAGIYVCEPEMLELLN 174

Query: 186 QVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           + +  +  E     + ++ ++ G +   L+     W+D G  D  ++A+   +
Sbjct: 175 KNEYLDMPE-----LIKLAMQKGRVNTYLI--HDYWIDIGRLDEFVKANEDFK 220


>UniRef50_C8PUN5 Utp--glucose-1-phosphate uridylyltransferase n=1 Tax=Enhydrobacter
           aerosaccus SK60 RepID=C8PUN5_9GAMM
          Length = 295

 Score =  177 bits (450), Expect = 3e-43,   Method: Composition-based stats.
 Identities = 58/279 (20%), Positives = 110/279 (39%), Gaps = 45/279 (16%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +I   G GTR+ P+++ V K+LLP+ +KP I Y +   + AG+  I+++   +  G  +
Sbjct: 8   AVIPVAGFGTRMLPLSKAVPKELLPLGNKPAIQYVVEEAIAAGLTNIVLVNHAQKTG-IE 66

Query: 63  RLLGDGSEFG---------------------IQLEYAEQPSPDGLAQAFIIGETFLNGEP 101
                 SE                       + +    Q  P GL  A +     +  EP
Sbjct: 67  NYFDINSELDTQLRGKGKAALADSLNWLPAEVTVTSVRQGKPLGLGHAVLQARPIVGDEP 126

Query: 102 SCLVLGDNI-------FFGQGFSPKLRHVAARTEGATVFG-YQVMDPERFGVVEF----- 148
             ++L D I       +  Q  +  L+  A +     +    +  D  ++G+ +      
Sbjct: 127 FAVLLPDVILNPYNTDYTQQNLAYMLQQFAKQQHSQILVDPVKESDISKYGIAKLASTQM 186

Query: 149 ------DDNFRAISLEEKP--KQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSI 200
                 + +F      EKP  +   SN AV G Y +++ + +Y    +PS  GE+++T  
Sbjct: 187 VAKSEQNQSFAVTGFVEKPKAEDAPSNLAVVGRYVFNNAIFDYLANTQPSVGGEIQLTDA 246

Query: 201 NQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
               +      V+++       D G  +S ++A  +  T
Sbjct: 247 IDALISTQ--GVDVVSMVGNSFDAGDMNSYLQAVGYFAT 283


>UniRef50_B0THI4 D,d-heptose 1,7-bisphosphate phosphatase subfamily, putative n=1
           Tax=Heliobacterium modesticaldum Ice1 RepID=B0THI4_HELMI
          Length = 397

 Score =  177 bits (450), Expect = 3e-43,   Method: Composition-based stats.
 Identities = 54/265 (20%), Positives = 97/265 (36%), Gaps = 11/265 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +IL GG G RL  +T+ + K ++ I  KP +   ++ L   GI+ IL++        
Sbjct: 1   MQAVILVGGLGARLGTLTKKMPKPMMDIGGKPFLELIINNLKRFGIKNILLLVGYRCHDI 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                 DGS + + + Y+ +  P G   A ++    L  E   L+L  + FF       L
Sbjct: 61  I-DYFQDGSRWNVIIRYSIEREPAGTGGALLLASDKLEDE--FLLLNGDTFFDFNILDLL 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
             V        V        ER+G +  ++  R  S  EK    KS    +G+Y     +
Sbjct: 118 VRVPHGKWEFKVALTPSKSSERYGSIIINNENRVTSFVEKRTHLKSALINSGIYHVRKSI 177

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           ++Y   +  S         +    +    +   +      ++D G    L          
Sbjct: 178 LKYIDSIPCSLEN-----HVLPKIVSNEQMYGYIY--NGYFVDIGIPCDLERG-RMDLPD 229

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEG 265
            KR    +     I +  G++  + 
Sbjct: 230 RKRPAAFLDRDGVINYDKGYVHKKE 254


>UniRef50_B6AEL1 Nucleotidyl transferase family protein n=1 Tax=Cryptosporidium
           muris RN66 RepID=B6AEL1_9CRYT
          Length = 441

 Score =  177 bits (448), Expect = 6e-43,   Method: Composition-based stats.
 Identities = 49/249 (19%), Positives = 95/249 (38%), Gaps = 15/249 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK IIL+GG G+RL P+T    K ++ + + P+I + +S  +  G++ I++      +  
Sbjct: 1   MKAIILSGGFGSRLRPLTLSKPKPIIELCNIPLIEFQISQFVEVGVKNIILAVNYLSEEL 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNG----EPSCLVLGDNIFFGQGF 116
            + +     ++G+++  + +  P G A   ++ + F+           V   +I      
Sbjct: 61  REPIKNIEKKYGVKINASIEEKPLGTAGPILLAKRFIEDNIITNEPFFVCNSDIVCNFPL 120

Query: 117 SPKLRHV------AARTEGATVFGYQVMDPERFGVVEFD-DNFRAISLEEKPKQPKSNWA 169
              L           R     +   QV DP ++GVV  D D        EKP++   N+ 
Sbjct: 121 EEILTMYSKLNCDHQRKCEGIILVKQVEDPSKYGVVVHDRDTGLVEEFIEKPQKYIGNFI 180

Query: 170 VTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFA-WLDTGTHD 228
             GLY     ++      +P+    +E     ++        +  L      W D G   
Sbjct: 181 NAGLYILSPSILNLI---EPNIAVSIEKNIFPKIAARKSLYCLRFLTNEINIWADVGIPA 237

Query: 229 SLIEASTFV 237
             +  +   
Sbjct: 238 DFLYGTQLF 246


>UniRef50_B5ZR76 Nucleotidyl transferase n=12 Tax=Bacteria RepID=B5ZR76_RHILW
          Length = 237

 Score =  176 bits (447), Expect = 6e-43,   Method: Composition-based stats.
 Identities = 55/242 (22%), Positives = 95/242 (39%), Gaps = 12/242 (4%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           + +ILAGG GTRL P T  + K L+PI D P++   +  L+  G + I +    + +   
Sbjct: 4   RAVILAGGMGTRLRPYTVVLPKPLMPIGDYPILEVIIRQLISGGFQHITLAVNHQAE-LI 62

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLR 121
           +    DG ++G++++Y+ +  P G      + +         LV+  +I     ++    
Sbjct: 63  KAFFQDGDKWGVRIDYSLEDQPLGTMGPLRLIKDLPEN---FLVMNGDILTDLNYADFHD 119

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVV 181
                    T+          +GV++ ++        EKP          G+Y   S  V
Sbjct: 120 THVREGNIFTISSKTREHRIDYGVLDTNEAGLLTGFREKPTAEYK--VSMGVYMVSSGAV 177

Query: 182 EYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVE 241
           E+  Q     RG      +    L AG         G+ WLD G  D    A    +T++
Sbjct: 178 EHIPQ-----RGAYGFDQLMLDLLAAGKPATVRDFPGY-WLDIGRPDDYALAIEQFETMQ 231

Query: 242 KR 243
            R
Sbjct: 232 SR 233


>UniRef50_B8FX62 Glucose-1-phosphate adenylyltransferase n=2 Tax=Desulfitobacterium
           hafniense RepID=B8FX62_DESHD
          Length = 229

 Score =  176 bits (447), Expect = 6e-43,   Method: Composition-based stats.
 Identities = 62/238 (26%), Positives = 102/238 (42%), Gaps = 13/238 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ IILAGG G+RL P +R + K L PI DKP+    +  L  AG  E+++         
Sbjct: 1   MQTIILAGGRGSRLDPYSRILPKPLFPIGDKPIAAILIEQLKKAGTDEVIMCLGY-LSDL 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +    DGSEFG+ + Y+ +  P G A      E     + + +V+  +      F    
Sbjct: 60  LKTYFQDGSEFGLTIRYSVESEPLGTAGPLKGVEGL---QDNFVVVNGDELTTLDFRALY 116

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
            H  A     TV   +      FGV+E  D  + I+  EKP    + WA  G+Y  +  +
Sbjct: 117 EHHRAVQADMTVAVQKKTTHSSFGVLEIQD-GQVIAYAEKPT--LNYWASMGIYVINKDI 173

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           + Y    +     + ++ ++ Q  ++ G        +   W D GT   L +A   ++
Sbjct: 174 LSYIPDNE-----KYDMPNLVQCLIQNGAKVSSYESQDL-WFDIGTLGDLEKAKEQLE 225


>UniRef50_Q49VP4 UTP--glucose-1-phosphate uridylyltransferase 2 n=216 Tax=cellular
           organisms RepID=GTAB2_STAS1
          Length = 289

 Score =  176 bits (447), Expect = 8e-43,   Method: Composition-based stats.
 Identities = 66/271 (24%), Positives = 103/271 (38%), Gaps = 33/271 (12%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K II A G GTR  P T+ + K++LPI DKP I Y +     AGI +I+I+T    +   
Sbjct: 6   KAIIPAAGLGTRFLPATKAMPKEMLPILDKPTIQYIVEEAARAGIEDIIIVTGKHKRA-I 64

Query: 62  QRLLGDGSEFGI---------------------QLEYAEQPSPDGLAQAFIIGETFLNGE 100
           +    +  E  +                      + Y  Q    GL  A      F+  E
Sbjct: 65  EDHFDNQKELEMILQEKGKTDLLEKVKYSTELANIFYVRQKEQKGLGHAIYSARQFIGDE 124

Query: 101 PSCLVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQVMD---PERFGVVE----FDDNFR 153
           P  ++LGD+I      + K    A    G +V G Q +D     R+G+++    F   + 
Sbjct: 125 PFAVLLGDDIVESDNPAIKQLIEAYEETGKSVIGVQEVDEAQTHRYGIIDPLQKFGRKYE 184

Query: 154 AISLEEKPKQ--PKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLT 211
                EKPKQ    SN A+ G Y     + +Y         GE+++T   +    A    
Sbjct: 185 VNEFVEKPKQGTAPSNLAIMGRYVLTPDIFDYLATQGEGAGGEIQLTDAIERLNRADQ-- 242

Query: 212 VELLGRGFAWLDTGTHDSLIEASTFVQTVEK 242
           V          D G     ++ +      ++
Sbjct: 243 VYAYDFEGDRYDVGEKLGFVKTTIEYALKDE 273


>UniRef50_D2PFA0 Nucleotidyl transferase n=10 Tax=Sulfolobus RepID=D2PFA0_SULIS
          Length = 237

 Score =  175 bits (444), Expect = 1e-42,   Method: Composition-based stats.
 Identities = 56/242 (23%), Positives = 105/242 (43%), Gaps = 14/242 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M  +ILAGG G RL P+T    K L+ +  +P+I + +S L   GI   +I+T  + +  
Sbjct: 4   MHAVILAGGYGKRLRPLTDDRPKPLIEVAGRPIIEWQISWLKQFGITSFVILTGYKWEVL 63

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            + L  +    GI   ++ +  P G   A    E  L+ E + +VL  +I      S   
Sbjct: 64  IKWLSENEKRLGISTYFSIEEEPLGTGGALRKVERLLSTENTFIVLNGDIITNLDISKLK 123

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
               +     T+    +  P  +G+VE  D+ + I  +EKP   ++ W   G+Y    ++
Sbjct: 124 ---ISNENVMTMSLVPLKSP--YGIVETKDD-KIIDFKEKP-ILENYWINAGVYLMRKEI 176

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            +Y       E+G++E  +  ++  E+  + ++       W    T   + E S  +  +
Sbjct: 177 FKYLP-----EKGDMEKLTFPKLAKESLLIGIKYY--DVYWRSIDTIKDIEEVSEDLIKM 229

Query: 241 EK 242
           + 
Sbjct: 230 KN 231


>UniRef50_A1S194 UDP-glucose pyrophosphorylase n=1 Tax=Thermofilum pendens Hrk 5
           RepID=A1S194_THEPD
          Length = 299

 Score =  175 bits (444), Expect = 1e-42,   Method: Composition-based stats.
 Identities = 70/267 (26%), Positives = 111/267 (41%), Gaps = 36/267 (13%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPI--------YDKPMIYYPLSVLMLAGIREILIIT 53
           KG++LA G GTRL P ++ + K++LP+        Y KP+I         AGIRE   + 
Sbjct: 6   KGVLLAAGLGTRLVPYSKEMPKEMLPVFFGVNNSVYLKPVIQAVFEQFYEAGIREFCFVV 65

Query: 54  TPEDKGYFQRLLGDG------SEFGIQ-----------------LEYAEQPSPDGLAQAF 90
               +        D        + G                   + +  QP P G   A 
Sbjct: 66  GRGKRVIEDHFTPDWDFVEYLEKTGKNDYAELLRDFYEKVEKSYITWVNQPVPRGTGHAV 125

Query: 91  IIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQVMDPERFGVV---E 147
            + + F+  +       DN+F G+    +L     R     +   +V DP R+GVV    
Sbjct: 126 YMAKGFVGDDYFMAAATDNLFLGENIPRRLLEYFDRLRSPMLAVKRVRDPRRYGVVIGSR 185

Query: 148 FDDN-FRAISLEEKPKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLE 206
            D + +R   + EKP++P S  A T LY +  ++    +Q  PS RGELE+T   Q+ + 
Sbjct: 186 VDTSIYRVEGIVEKPREPLSYLANTSLYIFPPEIFRAIEQTTPSPRGELEVTDSIQILIR 245

Query: 207 AGNLTVELLGRGFAWLDTGTHDSLIEA 233
           +G            W+D GT ++ + A
Sbjct: 246 SGYQFYAY-EAEADWIDIGTWETFLRA 271


>UniRef50_C9XS92 Utp--glucose-1-phosphate uridylyltransferase (General stress
           protein 33) n=335 Tax=cellular organisms
           RepID=C9XS92_CLODC
          Length = 321

 Score =  175 bits (444), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 64/272 (23%), Positives = 109/272 (40%), Gaps = 33/272 (12%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K +I A G GTR  P T+   K++LPI DKP + Y +   + +GI EILIIT    K   
Sbjct: 7   KAVIPAAGLGTRFLPATKAQPKEMLPIVDKPTLQYIIEEAVASGIEEILIITGRNKKS-I 65

Query: 62  QRLLG-------DGSEFG--------------IQLEYAEQPSPDGLAQAFIIGETFLNGE 100
           +           D  + G              I + Y  Q  P GL  A      F+  E
Sbjct: 66  EDHFDKSVELELDLEKKGKKELLEVVQNISNMINIHYIRQKEPKGLGDAIYCARHFIGDE 125

Query: 101 PSCLVLGDNIFF-GQGFSPKLRHVAARTEGATVFGYQV--MDPERFGVVEFDD----NFR 153
           P  ++LGD+I         +L           +   +V   D  ++G++E  +     ++
Sbjct: 126 PFAVMLGDDIVDNDVPCLKQLTDAYEEYRTTILGVQKVNQEDTNKYGIIEAKNIEGRVYK 185

Query: 154 AISLEEKPK--QPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLT 211
              + EKP+  +  SN A+ G Y    ++ +  K + P + GE+++T   ++   +    
Sbjct: 186 VKDMVEKPESGKAPSNIAILGRYIITPEIFDILKDLPPGKGGEVQLTDALKIL--SKKEA 243

Query: 212 VELLGRGFAWLDTGTHDSLIEASTFVQTVEKR 243
           +          D G     +EA+      ++ 
Sbjct: 244 MYAYNFEGKRYDVGDKLGFLEATVDFALKKED 275


>UniRef50_D0XT48 Nucleotidyl transferase n=1 Tax=Brevundimonas subvibrioides ATCC
           15264 RepID=D0XT48_9CAUL
          Length = 356

 Score =  175 bits (444), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 52/231 (22%), Positives = 81/231 (35%), Gaps = 12/231 (5%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQR 63
           +I+AGG G RL P+T+   K +L +  +P++   +  L   G     +            
Sbjct: 125 VIMAGGRGVRLAPLTQTCPKPMLKVAGRPLLESIIERLRDQGFSRFRLAVNY-LAEVITD 183

Query: 64  LLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHV 123
             GDGS  G++++Y  +  P G A A  +    +      +VL  ++     F   +   
Sbjct: 184 HFGDGSAMGVEIDYLREDHPRGTAGALSLLREPVTA--PVVVLNGDVLTRLAFGDLIDFH 241

Query: 124 AARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEY 183
                 AT+   +       GV E  +  R  SL EKP       A  G+Y  D  ++  
Sbjct: 242 LEHGASATLCVREHQFQAPHGVAEI-EGVRLTSLREKPT--FRWQANAGIYCLDGSLLSR 298

Query: 184 AKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
                P +  E          L     TV        WLD G       A 
Sbjct: 299 IPADGPYDMPE------LLSALVGDGETVCAYPMHEYWLDIGRPPDFESAQ 343


>UniRef50_A1S0Y5 UDP-glucose pyrophosphorylase n=1 Tax=Thermofilum pendens Hrk 5
           RepID=A1S0Y5_THEPD
          Length = 296

 Score =  175 bits (443), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 65/274 (23%), Positives = 114/274 (41%), Gaps = 43/274 (15%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLP--------IYDKPMIYYPLSVLMLAGIREILIIT 53
           K +I A G GTRL PIT+ + K++LP        +  KP+I+     L+  G+ E+  I 
Sbjct: 4   KAVITAAGLGTRLLPITKELPKEMLPLFSVSDNAVGLKPIIHIVFESLLGVGVSEVCFIV 63

Query: 54  TPEDKGYFQRLLGDGSEF------------------------GIQLEYAEQPSPDGLAQA 89
               +   +      ++F                          ++ +  QP P G   A
Sbjct: 64  GKSKRA-IEDYFTPDADFIEVLRAKGVENRANELMKFYSAIRNAKIFFINQPEPRGFGDA 122

Query: 90  FIIGETFLNGEPSCLVLGDNIFFGQG---FSPKLRHVAARTEGATVFGYQVMDPERFGVV 146
            +  E F+  +P  +  GD+    +G       ++        AT+    V DP  +GV+
Sbjct: 123 VLRAEPFVGADPFIVHAGDDAVISEGHNHLRRLVKVFQEYDCDATLLAEDVEDPRAYGVL 182

Query: 147 E---FDDNF---RAISLEEKPKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSI 200
                +D     R + + EKP++P +N A   +Y +  K+  Y + VKP   GE+++T+ 
Sbjct: 183 RGKVVNDYGSILRVLDIIEKPREPPTNIAAIAVYAFKPKIFSYLRNVKPDSGGEVQLTAA 242

Query: 201 NQMYL-EAGNLTVELLGRGFAWLDTGTHDSLIEA 233
            +  + +  ++    L  G   LD GT  S  +A
Sbjct: 243 IKAMIDDGCDVCAVKLKPGERRLDVGTPQSYWKA 276


>UniRef50_D2EEQ5 Nucleotidyl transferase n=1 Tax=Candidatus Parvarchaeum acidiphilum
           ARMAN-4 RepID=D2EEQ5_9EURY
          Length = 274

 Score =  174 bits (441), Expect = 3e-42,   Method: Composition-based stats.
 Identities = 58/273 (21%), Positives = 120/273 (43%), Gaps = 24/273 (8%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K +I A G G+R++P+TR   K++LPI DKP+I++ +  ++ AGI +IL+I     +   
Sbjct: 6   KAVIPAAGLGSRMYPLTRAQPKEMLPILDKPVIHHVVDEILSAGIDQILVIVGKGKESII 65

Query: 62  QRLLGDGSEFGIQ---------LEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIF- 111
                D +E  ++         + +  Q    GLA A    + F+N EP  ++ GD I+ 
Sbjct: 66  NYF--DYNELDLKFNSMPDFPEIFFVRQREQKGLADAVKYAKKFVNDEPFMVLAGDTIYG 123

Query: 112 --FGQGFSPKLRHVAARTEGATVFG--YQVMDPERFGVVEFDDNFR----AISLEEKPK- 162
               +  + ++  V  R     +      +   + +G+V  D+  +      ++ EKP+ 
Sbjct: 124 SNKEKTIAQQIIDVFNRKSSTVIGLEKVPIEKVKHYGIVNGDEIEKGLHLIKNMVEKPEI 183

Query: 163 -QPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAW 221
            +  SN A+T  Y     +  +  ++KP +  E ++T    +  +  ++    +      
Sbjct: 184 SEAPSNLAITAAYALQPDIFAFIDKIKPGKNNEYQLTDALNLMCKEQDVFG--IEIDGKR 241

Query: 222 LDTGTHDSLIEASTFVQTVEKRQGFKIACLEEI 254
            D G+ +  +E        ++R  +     + +
Sbjct: 242 YDIGSKEFWVETFIEFARKDERFSYIFKNPDNL 274


>UniRef50_A3JPT4 Putative sugar-phosphate nucleotidyl transferase n=1
           Tax=Rhodobacterales bacterium HTCC2150
           RepID=A3JPT4_9RHOB
          Length = 496

 Score =  174 bits (441), Expect = 3e-42,   Method: Composition-based stats.
 Identities = 51/250 (20%), Positives = 101/250 (40%), Gaps = 20/250 (8%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K ++LA G G+R  P+T  + K +LPI  +P+I + L      G+ +++I          
Sbjct: 116 KAVVLAAGKGSRCAPLTFNMPKPMLPILGRPIIEHLLEHFGRFGLEDVVINPVYLGPQII 175

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDG-------LAQA---FIIGETFLNGEPSCLVLGDNIF 111
           Q  L  G+ FG  ++YA +    G       +  A     + +          V   +  
Sbjct: 176 QH-LKCGAAFGKHIQYANEGHFKGELWWDNAIGSASSLLKMHQENAAFFDDFFVFCGDAL 234

Query: 112 FGQGFSPKLRHVAARTEGATVFGYQVMDP--ERFGVVEFDDNFRAISLEEKPK--QPKSN 167
                +  +          T+   +V     E+FG+++ +   +  + +EKPK  +  SN
Sbjct: 235 IDLNLAEMMEQHKRSGAAVTIAAQRVDPTCVEKFGIIDCNSLDQITAFQEKPKISEAISN 294

Query: 168 WAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTH 227
            A TG+Y ++  +++    ++  + G    T +    L A  + + +    F WLD G  
Sbjct: 295 LANTGIYIFNPSILDKIPLIQACDIG----THLLPKLL-AEGVDLNVYQSTFTWLDVGCG 349

Query: 228 DSLIEASTFV 237
               + +  +
Sbjct: 350 KDFFDTNHKI 359


>UniRef50_Q9I291 UTP--glucose-1-phosphate uridylyltransferase n=168 Tax=cellular
           organisms RepID=GALU_PSEAE
          Length = 279

 Score =  174 bits (441), Expect = 4e-42,   Method: Composition-based stats.
 Identities = 68/278 (24%), Positives = 120/278 (43%), Gaps = 39/278 (14%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITT------- 54
           K +  A G GTR  P T+ + K++LP+ +KP+I Y +   + AG+ EI I+T        
Sbjct: 4   KCLFPAAGYGTRFLPATKAMPKEMLPVVNKPLIQYAVEEALEAGLSEIGIVTGRGKRSLE 63

Query: 55  ------PEDKGYFQRLLGDGSEFGIQLE---------YAEQPSPDGLAQAFIIGETFLNG 99
                  E +   +    D  ++ + +          Y  Q    GL  A + G   +  
Sbjct: 64  DHFDISYELEHQIRN--TDKEKYLVGIRRLIDECTFAYTRQVEMKGLGHAILTGRPLIGD 121

Query: 100 EPSCLVLGDNIFFGQGFSPKLRHVAARTEG--ATVFGYQVMDPE---RFGVV----EFDD 150
           EP  +VL D++         L+ +         ++   Q + PE   ++GV+      DD
Sbjct: 122 EPFAVVLADDLCLNLEGDSVLKQMVKLYNQFRCSIVAIQEVPPEETNKYGVIAGEMIRDD 181

Query: 151 NFRAISLEE--KPKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITS-INQMYLEA 207
            FR  ++ E  KP++  SN A+ G Y     + +  +Q +P + GE++IT  + +   + 
Sbjct: 182 IFRVNTMVEKPKPEEAPSNLAIIGRYILTPDIFDLIEQTEPGKGGEIQITDALMKQAQDG 241

Query: 208 GNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEKRQG 245
             L  +  G+ F   D G+ +  IEA+ F      + G
Sbjct: 242 CVLAYKFKGKRF---DCGSAEGYIEATNFCYENLYKTG 276


>UniRef50_Q8DE01 Nucleoside-diphosphate-sugar pyrophosphorylase n=1 Tax=Vibrio
           vulnificus RepID=Q8DE01_VIBVU
          Length = 348

 Score =  173 bits (440), Expect = 4e-42,   Method: Composition-based stats.
 Identities = 54/236 (22%), Positives = 93/236 (39%), Gaps = 13/236 (5%)

Query: 5   ILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQRL 64
           ++AGG GTRL P+T    K LL + ++P++   +   + +G     I T           
Sbjct: 124 LMAGGFGTRLKPLTDNCPKPLLKVGERPILETVILSFIRSGFSNFYIST-HYLPEMIHEA 182

Query: 65  LGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHVA 124
           LGDGS +G+ ++Y  + +P G   A  +    L   P  +V+  +I     F   L    
Sbjct: 183 LGDGSRWGVSIQYIHEETPLGTGGALGLLPDSLPDLP-VIVMNGDILTKINFEDVLEFHN 241

Query: 125 ARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEYA 184
                AT+   +      FGV+E  D F+   + EKP          G+Y  +  ++   
Sbjct: 242 KNDSKATMCVREFEYQVPFGVIEAQD-FKITGIVEKPTY--RFHVNAGIYVLNKSLITSV 298

Query: 185 KQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
                  +GE     +  ++ +     + +      WLD G  D    A   + T+
Sbjct: 299 ------AKGEYL--DMPTLFEQQIGRDIHVFPFHEYWLDIGRMDDYKRAQVDILTL 346


>UniRef50_C2KXR6 Glucose-1-phosphate cytidylyltransferase n=1 Tax=Oribacterium sinus
           F0268 RepID=C2KXR6_9FIRM
          Length = 239

 Score =  173 bits (439), Expect = 5e-42,   Method: Composition-based stats.
 Identities = 55/235 (23%), Positives = 90/235 (38%), Gaps = 11/235 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ I+L GG GTRL  +     K +  I  KP + Y L +L   GI E++          
Sbjct: 1   MQAILLCGGMGTRLRSVVSDRPKPMADICGKPFLQYLLEMLREKGITEVIFALGY-MGEM 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +    DGS FG+++ Y+ +  P G   A       +  E   LVL  + +F   +    
Sbjct: 60  IEEYFQDGSAFGLKIAYSYEEDPLGTGGAIRNALPKIMEEE-VLVLNADTYFPMDYQGLY 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK---QPKSNWAVTGLYFYD 177
           R         ++    V D  R+G V  D   R ++  EK +   QP +     G+Y   
Sbjct: 119 RFHQENDGDFSLATRAVPDISRYGAVRRDVAGRILAWNEKLEDGGQPLAGEINGGIYVMK 178

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIE 232
             ++    + K S   +         +L  G     L   G+ ++D G      +
Sbjct: 179 KSLIAEIPEGKQSLEQDC-----VPKWLSEGKRIFGLPFDGY-FMDIGIPKDYQQ 227


>UniRef50_D1C4F4 Nucleotidyl transferase n=1 Tax=Sphaerobacter thermophilus DSM
           20745 RepID=D1C4F4_SPHTD
          Length = 337

 Score =  173 bits (439), Expect = 6e-42,   Method: Composition-based stats.
 Identities = 61/244 (25%), Positives = 101/244 (41%), Gaps = 17/244 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M  II   G GTRL P T    K L+ +  KP++ + L  L+   I +++ +T       
Sbjct: 1   MNIIIPVAGLGTRLRPQTWSKPKPLVSVAGKPVLGHVLDRLLALPIDKVVFVTGY-LGDQ 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  +     F     + EQ    G + A I     + G P+ +V  D       F   L
Sbjct: 60  IEDYVRQNYRFDA--TFVEQKEQLGQSHAIIQARGEVTG-PTLVVFPD-----MLFEADL 111

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDS-- 178
             ++  T    +F  +V DP RFGV+E  +N R   L EKP+   SN A+ G+Y++ +  
Sbjct: 112 DQISGLTADGALFVKEVDDPRRFGVIEV-ENGRITRLVEKPETMVSNLAIVGIYYFRAVE 170

Query: 179 ---KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAST 235
                ++Y        +GE  +    Q  ++ G     L      W D G   +L+  + 
Sbjct: 171 DLFDAIDYQMAHNIQTKGEYFLADAIQHMIDQGTHFTYLPVT--VWEDCGNPKALLNTNR 228

Query: 236 FVQT 239
           ++  
Sbjct: 229 YLLA 232


>UniRef50_C1VEK9 Nucleoside-diphosphate-sugar pyrophosphorylase family protein n=1
           Tax=Halogeometricum borinquense DSM 11551
           RepID=C1VEK9_9EURY
          Length = 390

 Score =  173 bits (439), Expect = 6e-42,   Method: Composition-based stats.
 Identities = 62/250 (24%), Positives = 107/250 (42%), Gaps = 11/250 (4%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            ++LA G G RL P+T+ + K +LP+ ++P+I Y L  L+ +GI  ++++         Q
Sbjct: 7   AVVLAAGEGRRLRPLTKYLPKPMLPVANRPVIDYVLDALVESGIERVVVVVGYR-GDRIQ 65

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
             L      G  +E+ +QPS  G   A +     +NGE   +V GD+I      +  L  
Sbjct: 66  THLT-AEYKGANIEFVQQPSRLGSGHALLQATGMVNGE-FLVVNGDSIINAAIVTSTLER 123

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
             +    ATV       PE +GVV  +       ++E P + +      G+Y +D  V  
Sbjct: 124 YDSTDCAATVAVAHSDTPEEYGVVITNRGL-IADIDEHPVEREGYVVNAGVYVFDESVFA 182

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEK 242
              + +P  +GE+ +T   +      +  V  +     WLD  T   L+  S  +     
Sbjct: 183 ALDRTEP-WQGEIRLTDAIEHL----DGPVTSILVNGGWLDPSTPWQLLSVSETLLG--S 235

Query: 243 RQGFKIACLE 252
           R G  +   +
Sbjct: 236 RFGSDVYVAD 245


>UniRef50_A2U039 Nucleotidyl transferase n=1 Tax=Polaribacter sp. MED152
           RepID=A2U039_9FLAO
          Length = 348

 Score =  173 bits (438), Expect = 7e-42,   Method: Composition-based stats.
 Identities = 53/239 (22%), Positives = 93/239 (38%), Gaps = 12/239 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +I+AGG GTRL P+T    K LL I +KP++ + L  L L GI +             +
Sbjct: 121 AVIMAGGKGTRLRPLTDNTPKPLLKIGEKPIMEHNLDRLCLYGIDDYWFSVKY-LGEQIE 179

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
              G+G +  I ++Y  + +P G   A    + F       L+   +I     +      
Sbjct: 180 GYFGNGKDKNINIQYVWEDNPLGTIGAVSKIKNF--EHDYILLTNSDILTNLDYEHFFLD 237

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
              +    +V          + V+E  D     S +EKP    + ++  G+Y     V++
Sbjct: 238 FLKQEADFSVVTIPYRVNVPYAVLETSDR-EITSFKEKPSY--TYYSNGGIYLMKKSVLK 294

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVE 241
           Y       E      T + +  ++ G   V      + WLD G H+   +A   +  ++
Sbjct: 295 YLP-----EEVFYNATDLMEKLIKEGKKVVSYPLSSY-WLDVGKHEDFEKAQKDINQIK 347


>UniRef50_Q1LK18 UDP-glucose pyrophosphorylase n=21 Tax=Proteobacteria
           RepID=Q1LK18_RALME
          Length = 299

 Score =  173 bits (438), Expect = 8e-42,   Method: Composition-based stats.
 Identities = 59/270 (21%), Positives = 110/270 (40%), Gaps = 36/270 (13%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K +    G GTR  P T+   K++LP+ DKP+I Y +   M AGI E++ +T    +   
Sbjct: 7   KAVFPVAGLGTRFLPATKASPKEMLPVVDKPLIQYAVEEAMAAGITEMIFVTGRSKRA-I 65

Query: 62  QRLLGDGSEF----------------------GIQLEYAEQPSPDGLAQAFIIGETFLNG 99
           +       E                        ++  Y  QP   GL  A +     +  
Sbjct: 66  EDHFDKAYELEAELEAKNKQALLDVVRSIKPANVECYYVRQPEALGLGHAVLCAAKLVGD 125

Query: 100 EPSCLVLGDNIFFGQGFSPKLRHVAA--RTEGATVFGYQVMDPER---FGVVEFDD-NFR 153
            P  ++L D++  G    P ++ +         +V G + + PE+   +GV++  + + R
Sbjct: 126 TPFAVMLADDLLDGGKDLPVMKQMVDIYNHYNCSVLGVEEIAPEQSRSYGVIDGREWDDR 185

Query: 154 AIS---LEEK--PKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAG 208
            I    + EK  P++  SN  V G Y    ++ ++ +++KP   GE+++T   Q  L+  
Sbjct: 186 VIKMSAIVEKPAPEKAPSNLGVVGRYILTPRIFDHIRELKPGAGGEIQLTDAIQSMLDQE 245

Query: 209 NLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
            +            D G+    ++A+    
Sbjct: 246 QVLAYRYK--GVRYDCGSKLGYLKATVEFA 273


>UniRef50_A3WUE7 Nucleoside-diphosphate-sugar pyrophosphorylase n=1 Tax=Nitrobacter
           sp. Nb-311A RepID=A3WUE7_9BRAD
          Length = 349

 Score =  173 bits (438), Expect = 8e-42,   Method: Composition-based stats.
 Identities = 50/239 (20%), Positives = 87/239 (36%), Gaps = 16/239 (6%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQR 63
           +I+AGG G RL  +T    K +L +  +P++   +S     G   IL+      +   + 
Sbjct: 123 VIMAGGRGARLAELTSETPKPMLKVGSRPLLETIISSFSQQGFHRILLAVGYRARQ-IED 181

Query: 64  LLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPS--CLVLGDNIFFGQGFSPKLR 121
             GDGS FG+ + Y  +  P G A A     + L  +P+   +V   ++   + +   L 
Sbjct: 182 HFGDGSSFGVDISYLREDKPLGTAGAL----SLLTEQPTLPLVVTNADLLTKEDYGHMLD 237

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVV 181
                    T+          FGVV  +      ++EEKP Q  S     G+Y      +
Sbjct: 238 RHVESRVDGTMAVRTYDMQVPFGVVRENGAG-IEAIEEKPIQ--SFIVNAGMYVLSPSSL 294

Query: 182 EYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
               +         ++ S+    +    +T         WLD G       A+     +
Sbjct: 295 GLIPK-----NATFDMPSLFDAMM-KHGMTTRCHHIDGYWLDIGRMADYERANVDFAEI 347


>UniRef50_A2EDD6 Nucleotidyl transferase family protein n=2 Tax=Trichomonas
           vaginalis RepID=A2EDD6_TRIVA
          Length = 352

 Score =  173 bits (438), Expect = 8e-42,   Method: Composition-based stats.
 Identities = 60/247 (24%), Positives = 103/247 (41%), Gaps = 12/247 (4%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            ++L GG GTRL P+T   SK L+   +K M  + L  L+ A  ++I++  + E +   +
Sbjct: 10  ALVLVGGFGTRLRPLTFTCSKPLVEFCNKHMCEFMLDALVAANCKKIILALS-ELQDDLK 68

Query: 63  RLLGDGSE--FGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           R +    +   GI++  + +  P G A    +    L G     +L  +I     F+  L
Sbjct: 69  RFIESYQQAHPGIEVIPSIEIEPLGTAGPIALARKHLKGHRFF-MLNSDIMSIYPFTDLL 127

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWA-VTGLYFYDSK 179
           ++       AT+    V D  R+GV++ D         EKP +   N A   G Y  +  
Sbjct: 128 KYHMNHDGEATIMSINVEDGSRYGVIDSDAEGVVTGFREKPTENNKNVAINAGHYILEPS 187

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           VV+   +   S   E+     ++  L        ++     W+D GT  + +EA    + 
Sbjct: 188 VVDLIPEKFCSIEREIFPEIASRKQL-------HVMKLQGHWMDIGTPQAFLEAIPLAKE 240

Query: 240 VEKRQGF 246
             K Q F
Sbjct: 241 TLKIQSF 247


>UniRef50_A4E9G8 Putative uncharacterized protein n=1 Tax=Collinsella aerofaciens
           ATCC 25986 RepID=A4E9G8_9ACTN
          Length = 302

 Score =  172 bits (437), Expect = 9e-42,   Method: Composition-based stats.
 Identities = 70/305 (22%), Positives = 116/305 (38%), Gaps = 45/305 (14%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLML-AGIREILIITTPEDKG 59
           MK II A G GTR  P T+   K++LP+ DKP+I Y +   +    + + +I+T+P    
Sbjct: 1   MKAIIPAAGLGTRFLPGTKCTPKEMLPVLDKPVIQYVVEEALDPEEVDDAIIVTSPGKPE 60

Query: 60  YFQRLLGDGS-------------------EFGIQLEYAEQPSPDGLAQAFIIGETFLNGE 100
                  D S                     G+ +++  Q  P GL  A       + GE
Sbjct: 61  LLSYFQPDRSLENLLRERGKDAYADAVAHAGGMPVDFRYQYEPKGLGHAIRSAADAVAGE 120

Query: 101 PSCLVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQVMDPE---RFGVVEFDDNF----- 152
              ++LGD +   +    K+  V+    GA+V       PE   R+GV+  D        
Sbjct: 121 NFLVLLGDYVVPNRDICDKMLAVSKEHGGASVIAVAACAPEEVSRYGVIAGDRVGSLEGF 180

Query: 153 ------------RAISLEEK--PKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEIT 198
                       R   L EK  P+   SN  + G Y     V++     +  + GE+++T
Sbjct: 181 ENAADDEPGAVWRIGGLVEKPAPEAAPSNLYIVGRYLLSPLVMDLLADQQAGKGGEIQLT 240

Query: 199 SINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEKRQGFKIACLEEIAWRN 258
                 L+   +   ++    +  DTGT    +  +  +   + R  F  A  + I  R 
Sbjct: 241 DAMARSLDREAM-YAVVIDPLSGYDTGTPSGWMATNALMAASDPR--FAGAFWDAIDERG 297

Query: 259 GWLDD 263
           G +  
Sbjct: 298 GLMRK 302


>UniRef50_P0C0I9 UTP--glucose-1-phosphate uridylyltransferase 1 n=116 Tax=cellular
           organisms RepID=HASC1_STRP1
          Length = 304

 Score =  172 bits (437), Expect = 1e-41,   Method: Composition-based stats.
 Identities = 59/271 (21%), Positives = 103/271 (38%), Gaps = 37/271 (13%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K II A G GTR  P T+ ++K++LPI DKP I + +   + +GI EIL++T    +   
Sbjct: 6   KAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEEALKSGIEEILVVTGKAKRS-I 64

Query: 62  QRLLGDGSEF--------------------GIQLEYAEQPSPDGLAQAFIIGETFLNGEP 101
           +       E                      I L +  Q  P GL  A +  + F+  EP
Sbjct: 65  EDHFDSNFELEYNLQAKGKNELLKLVDETTAINLHFIRQSHPRGLGDAVLQAKAFVGNEP 124

Query: 102 SCLVLGDNIF-----FGQGFSPKLRHVAARTEGATVFGYQV--MDPERFGVVEFDDN--- 151
             ++LGD++        +  + +L     +T  +T+   +V   D   +GV+        
Sbjct: 125 FVVMLGDDLMDITNASAKPLTKQLMEDYDKTHASTIAVMKVPHEDVSSYGVIAPQGKAVK 184

Query: 152 --FRAISLEEK--PKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEA 207
             +   +  EK  P+   S+ A+ G Y    ++    ++  P    E+++T         
Sbjct: 185 GLYSVDTFVEKPQPEDAPSDLAIIGRYLLTPEIFGILERQTPGAGNEVQLTDAIDTL--N 242

Query: 208 GNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
               V          D G     ++ S    
Sbjct: 243 KTQRVFAREFKGNRYDVGDKFGFMKTSIDYA 273


>UniRef50_C4RN52 UTP-glucose-1-phosphate uridylyltransferase galU n=4
           Tax=Actinomycetales RepID=C4RN52_9ACTO
          Length = 333

 Score =  172 bits (436), Expect = 1e-41,   Method: Composition-based stats.
 Identities = 62/282 (21%), Positives = 113/282 (40%), Gaps = 36/282 (12%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +K +I A G  TR  P T+ V K+LLP+ D+P++ + +     AGI ++L+IT       
Sbjct: 20  VKAVIPAAGLATRFLPATKAVPKELLPVVDRPVLQFIVEEATQAGIGDVLLITGRGKTSM 79

Query: 61  FQRL------------LGDGSEFG--------IQLEYAEQPSPDGLAQAFIIGETFLNGE 100
                            GD              ++    QP   GL  A    E+ +  +
Sbjct: 80  VDHFDRRPDLEARLESKGDTERLAAVRGPSELAEIYTCRQPEQLGLGHAVGYAESHVGDQ 139

Query: 101 PSCLVLGDNIF-FGQGFSPKLRHVAARTEGATVFGYQVMDPE--RFGVVEFD-------- 149
           P  ++LGD      +   P +  + ART G  +  ++V   E  R+G+   +        
Sbjct: 140 PFAVLLGDEFVKPSEPLLPAMLELQARTGGIVLAFFEVDPAETKRYGIASVEAAEPELTD 199

Query: 150 --DNFRAISLEE--KPKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYL 205
             +  +   + E  KP+   SN AV G Y    ++ +  ++ +P   GE+++T   ++  
Sbjct: 200 IGEVVKVTGMVEKPKPEDAPSNLAVLGRYVLPGRIFDAIRRTEPGSGGEIQLTDAMELLR 259

Query: 206 EAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEKRQGFK 247
             G     ++ RG    DTG     ++    +    +  G +
Sbjct: 260 TEGVPVHAIVYRGTR-YDTGMPLGYLQTVVQIACEREDLGAE 300


>UniRef50_B9CMC2 Glucose-1-phosphate adenylyltransferase n=1 Tax=Atopobium rimae
           ATCC 49626 RepID=B9CMC2_9ACTN
          Length = 381

 Score =  172 bits (436), Expect = 1e-41,   Method: Composition-based stats.
 Identities = 62/266 (23%), Positives = 101/266 (37%), Gaps = 26/266 (9%)

Query: 1   MK-----GIILAGGSGTRLHPITRGVSKQLLPIYDK-PMIYYPLSVLMLAGIREILIITT 54
           MK      ++LAGG G+RL  +T  V+K  +    K  +I + LS  + +GI  + ++T 
Sbjct: 1   MKKKECLAMLLAGGQGSRLGALTSNVAKPAVSFGGKFRIIDFALSNCVNSGISTVGVLTQ 60

Query: 55  PEDKGYFQRLLGDGSEF-------GIQL-----EYAEQPSPDGLAQAFIIGETFL--NGE 100
                     +G GS +       G+ +             +G A A      ++  N  
Sbjct: 61  YRPY-LLHSYIGTGSAWDLDDLGGGVSILPPFATQKGGAWYEGTADAVTQNIDYIEQNDS 119

Query: 101 PSCLVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQV--MDPERFGVVEFDDNFRAISLE 158
              L+L  +  +   +   L          T+    V   +  RFG++  DD+ R     
Sbjct: 120 EYVLILSGDQLYRMDYGEMLACHKEHNADLTIAVMPVPWEEASRFGIITVDDDGRITKFS 179

Query: 159 EKPKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEI--TSINQMYLEAGNLTVELLG 216
           EKP  P SN A  G+Y + ++++  A Q    ++         +    LE G        
Sbjct: 180 EKPTHPDSNLASMGIYVFSTELLLKALQEDALDQQSTHDFGKDVIPRLLEDGKRLYSYRF 239

Query: 217 RGFAWLDTGTHDSLIEASTFVQTVEK 242
            GF W D GT  S  E S  +   E 
Sbjct: 240 EGF-WRDVGTISSYHETSMDLLGPEP 264


>UniRef50_A4X2X2 UDP-glucose pyrophosphorylase n=3 Tax=Actinomycetales
           RepID=A4X2X2_SALTO
          Length = 318

 Score =  172 bits (436), Expect = 1e-41,   Method: Composition-based stats.
 Identities = 64/280 (22%), Positives = 112/280 (40%), Gaps = 34/280 (12%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +K +I A G  TR  P T+ V K+LLP+ D+P++ Y +     AGI ++L+IT       
Sbjct: 21  VKAVIPAAGLATRFLPATKAVPKELLPVVDRPVLQYIVEEATEAGITDVLLITGRGKTSM 80

Query: 61  FQRL--LGDGSEFGIQ----------------LEYAEQPSPDGLAQAFIIGETFLNGEPS 102
                   D  E   +                +    QP   GL  A    E+ +  +P 
Sbjct: 81  VDHFDRRPDLEERLAKKPELLAAVKRTEDLAAIYTCRQPEQLGLGHAVGYAESHIGDQPF 140

Query: 103 CLVLGDNIF-FGQGFSPKLRHVAARTEGATVFGYQVMDPE--RFGV----------VEFD 149
            ++LGD      +   P +  + ART G  +  ++V   E  R+G+           +  
Sbjct: 141 AVLLGDEFVKPTEPLLPAMLELQARTGGIVLAFFEVDPDETTRYGIASVAPAEAEFADIA 200

Query: 150 DNFRAISLEEK--PKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEA 207
           +  R   + EK  P++  SN AV G Y    ++ +   + +P   GE+++T   ++    
Sbjct: 201 EVVRVTGMVEKPEPEEAPSNLAVLGRYVLPGRIFDAIHRTEPGSGGEIQLTDAMEILRTE 260

Query: 208 GNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEKRQGFK 247
           G     ++ RG    DTG     ++    +       G +
Sbjct: 261 GVPVHAIVYRGTR-YDTGMPLGYLQTVVQIAAERDDLGAE 299


>UniRef50_B2UH51 UTP-glucose-1-phosphate uridylyltransferase n=127 Tax=Bacteria
           RepID=B2UH51_RALPJ
          Length = 317

 Score =  172 bits (435), Expect = 2e-41,   Method: Composition-based stats.
 Identities = 65/270 (24%), Positives = 111/270 (41%), Gaps = 38/270 (14%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K +    G GTR  P T+   K++LPI DKP+I Y +     AGI E++ IT    +   
Sbjct: 7   KAVFPVAGLGTRFLPATKASPKEMLPIVDKPLIQYAVEEAAAAGITEMIFITGRAKRA-I 65

Query: 62  QRLLGDGSEF----------------------GIQLEYAEQPSPDGLAQAFIIGETFLNG 99
           +       E                       G++  Y  QP   GL  A +  +  +  
Sbjct: 66  EDHFDKAYELETELAAKNKQALLDMVQSIKPAGVECFYVRQPETLGLGHAVLCAQKLVRD 125

Query: 100 EPSCLVLGDNIFFGQ-GFSPKLRHVAARTEGATVFGYQVMDPE---RFGVV---EFDDNF 152
           EP  ++L D++   +     ++  +       ++ G + + PE    +GVV   E+DD  
Sbjct: 126 EPFAVILADDLLDHEPPVMQQMTELYDHYR-CSIVGVETIAPEATRSYGVVAGREWDDRL 184

Query: 153 -RAISLEEK--PKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYL-EAG 208
            +   + EK  P +  SN  V G Y    ++ ++ + ++P   GEL++T   Q  L E  
Sbjct: 185 VKLDGIVEKPAPSEAPSNLGVVGRYILTPRIFDHLRNLRPGAGGELQLTDAIQSLLAEEQ 244

Query: 209 NLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
            L     G+ F   D G+    ++A+    
Sbjct: 245 ILAYRYRGQRF---DCGSKFGYLQATVEFA 271


>UniRef50_A8M980 Glucose-1-phosphate thymidyltransferase n=3 Tax=Thermoproteaceae
           RepID=A8M980_CALMQ
          Length = 353

 Score =  171 bits (434), Expect = 2e-41,   Method: Composition-based stats.
 Identities = 70/246 (28%), Positives = 107/246 (43%), Gaps = 8/246 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M G+IL  G G R+ P++  + K L+ I  KP++ Y +  L    +  I ++        
Sbjct: 1   MLGLILVAGIGERMRPLSYSIPKPLISILGKPLVAYTMDKLKDIDVSRIGLVVG-RFSEL 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIG-ETFLNGEPSCLVLGDNIFFGQGFSPK 119
           F     +     I + Y  Q    G+A A   G E     E   + LGDN +F + F+  
Sbjct: 60  FMDYFNNDPRLNIPVTYIRQERRLGIAHAIYRGIEEGFLREDFVVALGDN-YFSESFTRF 118

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSN-WAVTGLYFY-D 177
            R          +   +    +RFG     +  R + L EKP QP  N + VTGLYF+ D
Sbjct: 119 AREFLEGGYDVFIVLTRHQQFQRFGNAVV-EGGRVVRLIEKPNQPIPNSYVVTGLYFFRD 177

Query: 178 SKVVEYA-KQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTF 236
              V  A   ++PS RGE E+T + Q +++        L  G+ W D GT + LI+    
Sbjct: 178 PDAVAKAFSNLRPSARGEYEVTDLIQWFIDNNYRVGYSLTTGW-WKDMGTPEDLIDLVQL 236

Query: 237 VQTVEK 242
           +    K
Sbjct: 237 MLDDAK 242


>UniRef50_C7M360 UTP-glucose-1-phosphate uridylyltransferase n=2 Tax=Actinobacteria
           (class) RepID=C7M360_ACIFD
          Length = 296

 Score =  171 bits (434), Expect = 2e-41,   Method: Composition-based stats.
 Identities = 61/274 (22%), Positives = 104/274 (37%), Gaps = 33/274 (12%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K +I A G GTR  P T+   K++LP+ D+P I Y +   +  G+  IL++T    +   
Sbjct: 4   KVVIPAAGLGTRFLPATKAQPKEMLPVVDQPAIQYVVEEAVTHGLTNILVVTGRGKRS-I 62

Query: 62  QRLLGDGSEFGI---------------------QLEYAEQPSPDGLAQAFIIGETFLNGE 100
           +       E  +                     Q+ Y  Q  P GL  A  +    +  +
Sbjct: 63  EDHFDRAVELELLLARQEKFAELALVEHISHLGQIHYLRQGEPRGLGHAVSVAAQHVGRD 122

Query: 101 PSCLVLGDNIF-FGQGFSPKLRHVAARTEGATVFGYQVMDPERFG------VVEFDDNFR 153
           P  ++L D+I          +  +  RT  + +   +V  PER        VV+ D    
Sbjct: 123 PFVVMLADDIMGPASPLLADMLALHERTGASVLSLMEVP-PERIRLYGAAGVVDEDGVDY 181

Query: 154 AISLEEKP--KQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLT 211
             S+ EKP   +  SN A+TG Y +   + +   +  P + GE+++T      +E     
Sbjct: 182 VRSVVEKPDASEAPSNLAITGRYIFTPAIFDALAETPPGKGGEIQLTDAIARLIE-HEPV 240

Query: 212 VELLGRGFAWLDTGTHDSLIEASTFVQTVEKRQG 245
           V +   G    D G     + +   +       G
Sbjct: 241 VAVRFDGRHRYDIGDKLDYLRSVVELALQRPDLG 274


>UniRef50_C9RJ30 Nucleotidyl transferase n=1 Tax=Fibrobacter succinogenes subsp.
           succinogenes S85 RepID=C9RJ30_FIBSS
          Length = 306

 Score =  170 bits (432), Expect = 4e-41,   Method: Composition-based stats.
 Identities = 59/259 (22%), Positives = 106/259 (40%), Gaps = 14/259 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++   G+G RL P T  + K LLP+  K ++ + +   +     E + IT  +    
Sbjct: 1   MKIVLPVAGNGIRLRPYTENLPKCLLPVAGKTILDWIVDDALFLNPSETIFITGYKASA- 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
               L    E+G  +    Q +P GL +A  +   ++N +   L++  +  F    S   
Sbjct: 60  VDDFLKQKPEWGA-VRTVVQSNPQGLGEAISLALPYVNDDEPLLIILGDTLFEADLSIL- 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYD--- 177
                      ++ ++V DP+RFGV   D N     L EKP++  S+ A+ G+Y+     
Sbjct: 118 ----KNASENILYTFKVADPKRFGVAVTDKNGHIERLVEKPQEFVSDEAIVGIYYIKDVK 173

Query: 178 --SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAST 235
              + + Y  Q     +GE ++T   +  ++ G            WLD G  ++L+  + 
Sbjct: 174 ALKEALNYLMQNDIRTKGEFQLTDALERMIQGGCKFRTAPVE--KWLDCGLVETLLATNA 231

Query: 236 FVQTVEKRQGFKIACLEEI 254
            V          +   E I
Sbjct: 232 HVLNRNATTESPVDGAEII 250


>UniRef50_C7PVA0 Nucleotidyl transferase n=3 Tax=Bacteroidetes RepID=C7PVA0_CHIPD
          Length = 330

 Score =  170 bits (432), Expect = 4e-41,   Method: Composition-based stats.
 Identities = 59/244 (24%), Positives = 106/244 (43%), Gaps = 15/244 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK II   G+GT+L P T    K L+P+  + ++   +  L+ AGI E + +        
Sbjct: 1   MKAIIPVAGAGTKLRPHTYTQPKALIPLAGRTILSIIIDQLVEAGINEFVFVIGY-LGDK 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            Q  +       +   + +Q S +G   A ++    +  +   +VLGD I  G  F   +
Sbjct: 60  IQHYVQQ-KYPHLTCHFVQQNSREGTGHAILLTRQVVQDDEILIVLGDTICEG-NFQELI 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFY--DS 178
                    + +   +V DP  FGV E ++    + + EKP+ PKSN A+ G+Y      
Sbjct: 118 A-----APVSMLGLKKVDDPRNFGVAELNEENNIVRVVEKPQIPKSNQALVGVYKIKETP 172

Query: 179 KVVEYAKQVKPSERG---ELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAST 235
           ++ +  +Q    ++    E ++T   Q  +E G        +   W D G  D+L+E + 
Sbjct: 173 QLYDCLEQNILHQKKSHDEFQLTDALQCMIEHGVTFKTF--KVTNWFDCGRKDTLLETNA 230

Query: 236 FVQT 239
            + +
Sbjct: 231 ILLS 234


>UniRef50_A9BBF8 Nucleoside-diphosphate-sugar pyrophosphorylase n=1
           Tax=Prochlorococcus marinus str. MIT 9211
           RepID=A9BBF8_PROM4
          Length = 353

 Score =  170 bits (431), Expect = 4e-41,   Method: Composition-based stats.
 Identities = 47/234 (20%), Positives = 92/234 (39%), Gaps = 12/234 (5%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQR 63
           +I+AGG G+RL P T    K +L +  KP+I   +   +  G+ +  I      +     
Sbjct: 126 VIMAGGKGSRLKPHTNNCPKPMLHVNGKPIIEIIIRNCIDFGLTKFFISVNYLKEQII-N 184

Query: 64  LLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHV 123
            LGDGS  G+ +EY  +  P G A +  +    +    + L+L  ++         +   
Sbjct: 185 HLGDGSTLGVDIEYLYEDMPLGTAGSLHLLPKDIK--ETILILNGDVLTNLNLHGLINFH 242

Query: 124 AARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEY 183
                  T+   +      +GV++ D       L+EKP    S     G+Y  +  ++  
Sbjct: 243 QENNADITLCAREESTLIPYGVIKLDG-INVEELKEKPIH--SYLVNAGIYLINPGILRL 299

Query: 184 AKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
            +         L++ ++     + G+  +      + W+D G  ++L +A    
Sbjct: 300 IESNSY-----LDMPNLILKAKKNGSHIIAFPIHEY-WIDVGRPETLKQAHNEW 347


>UniRef50_B4U0Q7 UTP--glucose-1-phosphate uridylyltransferase HasC.2 n=24
           Tax=Bacteria RepID=B4U0Q7_STREM
          Length = 322

 Score =  170 bits (431), Expect = 5e-41,   Method: Composition-based stats.
 Identities = 58/271 (21%), Positives = 100/271 (36%), Gaps = 37/271 (13%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K II A G GTR  P T+ ++K++LPI DKP I + +   + AGI EIL++T    +   
Sbjct: 26  KAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEEALKAGIEEILVVTGKAKRS-I 84

Query: 62  QRLLGDGSEF--------------------GIQLEYAEQPSPDGLAQAFIIGETFLNGEP 101
           +       E                      I L +  Q  P GL  A +  + F+  EP
Sbjct: 85  EDHFDSNFELEYNLQAKGKTELLKLVDETTAINLHFIRQSHPRGLGDAVLQAKAFVGNEP 144

Query: 102 SCLVLGDNI--FFGQGFSPKLRHVAARTE---GATVFGYQVMD--PERFGVVEFDDN--- 151
             ++LGD++         P  + +    +    +T+   +V       +GV+        
Sbjct: 145 FVVMLGDDLMDITNPSAKPLTKQLIEDYDCTHASTIAVMRVPHEEVSNYGVIAPQGKAVK 204

Query: 152 --FRAISLEEKPK--QPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEA 207
             +   +  EKP   +  S+ A+ G Y    ++    ++  P    E+++T         
Sbjct: 205 GLYSVETFVEKPSPDEAPSDLAIIGRYLLTPEIFAILEKQAPGAGNEVQLTDAIDKL--N 262

Query: 208 GNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
               V          D G     ++ S    
Sbjct: 263 KTQRVFAREFKGERYDVGDKFGFMKTSLDYA 293


>UniRef50_Q3K1K4 Glucose-1-phosphate adenylyltransferase n=14 Tax=Lactobacillales
           RepID=GLGC_STRA1
          Length = 379

 Score =  170 bits (431), Expect = 5e-41,   Method: Composition-based stats.
 Identities = 68/289 (23%), Positives = 120/289 (41%), Gaps = 27/289 (9%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDK-PMIYYPLSVLMLAGIREILIITTPEDKG 59
           M  +ILAGG GTRL  +T+ ++K  +    +  +I + LS    +GI  + +IT  +   
Sbjct: 5   MLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALSNCANSGINNVGVITQYQPLE 64

Query: 60  YFQRLLGDGSEFGIQ-----LEYAEQPSP-------DGLAQAFIIGETFLN--GEPSCLV 105
                +G+GS +G+      +   +  S         G + A      +++       L+
Sbjct: 65  -LNTHIGNGSSWGLDGIDSGVTVLQPYSATEGNRWFQGTSHAIYQNIDYIDRINPEYVLI 123

Query: 106 LGDNIFFGQGFSPKLRHVAARTEGATVFGYQVM--DPERFGVVEFDDNFRAISLEEKPKQ 163
           L  +  +   +   L+         TV    V   +  RFG++  D N R +  EEKP+ 
Sbjct: 124 LSGDHIYKMNYDDMLQTHKDNLASLTVAVLDVPLKEASRFGIMNTDSNDRIVEFEEKPEH 183

Query: 164 PKSNWAVTGLYFYDSKVVEYAKQVKPSERGEL--EITSINQMYLEAGNLTVELLGRGFAW 221
           PKS  A  G+Y +D K +            ++     ++   YLE+G         G+ W
Sbjct: 184 PKSTKASMGIYIFDWKRLRTVLIDGEKNGIDMSDFGKNVIPAYLESGERVYTYNFDGY-W 242

Query: 222 LDTGTHDSLIEASTFVQTVEKR-----QGFKIACLEEIAWRNGWLDDEG 265
            D GT +SL EA+      + +     + +KI     IA  N ++ ++ 
Sbjct: 243 KDVGTIESLWEANMEYIGEDNKLHSRDRSWKIYSKNLIAPPN-FMTEDA 290


Searching..................................................done


Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_A3DED2 Nucleotidyl transferase n=8 Tax=Clostridium RepI...   317   3e-85
UniRef50_A4J6Z1 Nucleotidyl transferase n=3 Tax=Peptococcaceae R...   307   3e-82
UniRef50_D2AV47 Phosphoglucomutase/phosphomannomutase family pro...   306   8e-82
UniRef50_C8W233 Nucleotidyl transferase n=1 Tax=Desulfotomaculum...   305   1e-81
UniRef50_UPI0001C42A13 Nucleoside-diphosphate-sugar pyrophosphor...   305   1e-81
UniRef50_P55253 Glucose-1-phosphate thymidylyltransferase n=1508...   305   2e-81
UniRef50_A8KY05 Nucleotidyl transferase n=6 Tax=Actinomycetales ...   305   2e-81
UniRef50_C0GEN7 Nucleotidyl transferase n=1 Tax=Dethiobacter alk...   302   1e-80
UniRef50_A9B3S0 Nucleotidyl transferase n=6 Tax=Chloroflexi (cla...   301   2e-80
UniRef50_C0ZG53 Probable mannose-1-phosphate guanyltransferase n...   300   3e-80
UniRef50_A5N939 Predicted glucose-1-phosphate nucleotidyltransfe...   300   4e-80
UniRef50_Q5DIE4 Glucose-1-phosphate thymidylyltransferase n=109 ...   299   1e-79
UniRef50_Q6MF02 Glucose-1-phosphate thymidylyltransferase n=3 Ta...   297   3e-79
UniRef50_A3DK29 Nucleotidyl transferase n=13 Tax=Clostridia RepI...   297   3e-79
UniRef50_Q46AY8 Glucose-1-phosphate thymidylyltransferase n=4 Ta...   296   5e-79
UniRef50_B8CYH8 Phosphoglucomutase n=1 Tax=Halothermothrix oreni...   296   6e-79
UniRef50_Q2NES5 Predicted nucleoside-diphosphate-sugar pyrophosp...   295   9e-79
UniRef50_Q2RH64 Nucleotidyl transferase n=1 Tax=Moorella thermoa...   295   9e-79
UniRef50_UPI0001C418F3 UDP-N-acetylglucosamine diphosphorylase/g...   295   1e-78
UniRef50_C7ICW0 Nucleotidyl transferase n=1 Tax=Clostridium papy...   295   1e-78
UniRef50_B8I5R7 Nucleotidyl transferase n=1 Tax=Clostridium cell...   295   2e-78
UniRef50_A7NP37 Nucleotidyl transferase n=5 Tax=Chloroflexaceae ...   293   4e-78
UniRef50_Q97EX5 Mannose-1-phosphate guanyltransferase (Pyrophosp...   293   4e-78
UniRef50_C7NU65 Glucose-1-phosphate thymidyltransferase n=5 Tax=...   293   5e-78
UniRef50_A7GSW4 Nucleotidyl transferase n=73 Tax=cellular organi...   293   6e-78
UniRef50_C3LKU6 Nucleotidyl transferase family protein n=8 Tax=B...   293   7e-78
UniRef50_B5YF33 Mannose-1-phosphate guanyltransferase n=2 Tax=Di...   291   1e-77
UniRef50_A0Q1V6 Mannose-1-phosphate guanyltransferase (Pyrophosp...   290   4e-77
UniRef50_B9MMF1 Nucleotidyl transferase n=1 Tax=Anaerocellum the...   289   8e-77
UniRef50_B7GHA3 Nucleoside-diphosphate-sugar pyrophosphorylase f...   288   1e-76
UniRef50_C1DV53 Mannose-1-phosphate guanyltransferase n=4 Tax=ce...   288   2e-76
UniRef50_A3DL04 Nucleotidyl transferase n=1 Tax=Staphylothermus ...   288   2e-76
UniRef50_Q1AW30 Nucleotidyl transferase n=1 Tax=Rubrobacter xyla...   287   3e-76
UniRef50_C0LTM3 Glucose-1-phosphate thymidylyltransferase n=6 Ta...   287   3e-76
UniRef50_A6TTZ6 Nucleotidyl transferase n=1 Tax=Alkaliphilus met...   287   4e-76
UniRef50_C9RWA3 Nucleotidyl transferase n=7 Tax=Geobacillus RepI...   286   4e-76
UniRef50_C0GGS0 Nucleotidyl transferase n=1 Tax=Dethiobacter alk...   286   5e-76
UniRef50_Q3A0B4 Mannose-1-phosphate guanyltransferase n=10 Tax=D...   285   1e-75
UniRef50_B0BZX4 Phosphoglucomutase/phosphomannomutase family Nuc...   285   1e-75
UniRef50_Q7NNE0 Mannose-1-phosphate guanyltransferase n=5 Tax=Gl...   283   4e-75
UniRef50_C1SHR4 Nucleotidyltransferase n=1 Tax=Denitrovibrio ace...   283   6e-75
UniRef50_C7LZ98 Nucleotidyl transferase n=1 Tax=Acidimicrobium f...   282   1e-74
UniRef50_Q55689 Glucose-1-phosphate thymidylyltransferase n=52 T...   280   4e-74
UniRef50_Q0AV26 Mannose-1-phosphate guanyltransferase n=1 Tax=Sy...   279   7e-74
UniRef50_B0K747 Nucleotidyl transferase n=10 Tax=Thermoanaerobac...   278   1e-73
UniRef50_A7HN10 Glucose-1-phosphate thymidyltransferase n=9 Tax=...   278   2e-73
UniRef50_Q3Z778 Nucleotidyltransferase family protein n=5 Tax=De...   277   3e-73
UniRef50_UPI0001C315BB Nucleotidyl transferase n=1 Tax=Conexibac...   277   3e-73
UniRef50_Q8SQX7 MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE n=3 Tax=...   277   3e-73
UniRef50_B3QV42 Nucleotidyl transferase n=1 Tax=Chloroherpeton t...   276   6e-73
UniRef50_C6PCK2 Nucleotidyl transferase n=1 Tax=Thermoanaerobact...   276   9e-73
UniRef50_D1Y1R8 Glucose-1-phosphate thymidylyltransferase n=1 Ta...   274   2e-72
UniRef50_B3LAG9 Mannose-1-phosphate guanyltransferase, putative ...   274   2e-72
UniRef50_C0E9C6 Putative uncharacterized protein n=1 Tax=Clostri...   274   2e-72
UniRef50_C6A0S3 Nucleotidyl transferase family n=6 Tax=Thermococ...   273   4e-72
UniRef50_O27787 Mannose-1-phosphate guanyltransferase n=1 Tax=Me...   273   7e-72
UniRef50_D1JGY1 Putative bifunctional protein glmU n=1 Tax=uncul...   272   8e-72
UniRef50_A6CNU8 Mannose-1-phosphate guanyltransferase (Pyrophosp...   272   9e-72
UniRef50_Q8DLP2 Mannose-1-phosphate guanyltransferase n=9 Tax=Cy...   272   1e-71
UniRef50_O29921 Glucose-1-phosphate thymidylyltransferase (GraD-...   272   1e-71
UniRef50_Q0W4J0 Glucose-1-phosphate thymidylyltransferase n=2 Ta...   271   2e-71
UniRef50_Q9ZAE7 Glucose-1-phosphate thymidylyltransferase n=12 T...   271   2e-71
UniRef50_B8LVX3 Mannose-1-phosphate guanylyltransferase n=2 Tax=...   270   3e-71
UniRef50_Q1ASA7 Nucleotidyl transferase n=1 Tax=Rubrobacter xyla...   270   3e-71
UniRef50_D2PJ00 Glucose-1-phosphate thymidyltransferase n=15 Tax...   270   4e-71
UniRef50_Q8TWY9 Nucleoside-diphosphate-sugar pyrophosphorylase i...   270   5e-71
UniRef50_A6Q9R9 Mannose-1-phosphate guanylyltransferase n=3 Tax=...   269   8e-71
UniRef50_Q9KD03 Mannose-1-phosphate guanyltransferase n=1 Tax=Ba...   269   9e-71
UniRef50_A7GF11 Glucose-1-phosphate thymidylyltransferase n=9 Ta...   268   1e-70
UniRef50_A5D3D6 dTDP-glucose pyrophosphorylase n=5 Tax=Bacteria ...   268   2e-70
UniRef50_Q12TW4 Mannose-1-phosphate guanyltransferase n=11 Tax=E...   266   4e-70
UniRef50_Q97A91 Glucose-1-phosphate thymidylyltransferase n=2 Ta...   266   6e-70
UniRef50_B5GLJ2 NDP-1-glucose synthase n=1 Tax=Streptomyces clav...   265   1e-69
UniRef50_C7IJC3 Glucose-1-phosphate thymidylyltransferase n=1 Ta...   264   2e-69
UniRef50_UPI000038E60D glucose-1-phosphate thymidylyltransferase...   264   2e-69
UniRef50_C7XIA2 Glucose-1-phosphate thymidylyltransferase n=1 Ta...   264   2e-69
UniRef50_Q8ILP1 Mannose-1-phosphate guanyltransferase, putative ...   264   2e-69
UniRef50_C0ZCI7 Probable glucose-1-phosphate thymidylyltransfera...   264   3e-69
UniRef50_A4I048 Mannose-1-phosphate guanyltransferase n=5 Tax=Le...   264   3e-69
UniRef50_A7AUL2 Mannose-1-phosphate guanyltransferase, putative ...   263   5e-69
UniRef50_B0PFA5 Putative uncharacterized protein n=1 Tax=Anaerot...   263   6e-69
UniRef50_C8NLU6 Mannose-1-phosphate guanyltransferase n=88 Tax=A...   262   1e-68
UniRef50_A6UP85 Glucosamine-1-phosphate N-acetyltransferase n=6 ...   261   2e-68
UniRef50_Q74B34 Nucleotidyltransferase family protein n=1 Tax=Ge...   261   2e-68
UniRef50_UPI000186E54F Mannose-1-phosphate guanyltransferase, pu...   261   3e-68
UniRef50_C6A1S5 NDP-sugar synthase n=9 Tax=Thermococcaceae RepID...   261   3e-68
UniRef50_Q46AY5 Glucose-1-phosphate thymidylyltransferase n=4 Ta...   260   3e-68
UniRef50_Q67QD8 Putative mannose-1-phosphate guanyltransferase n...   260   4e-68
UniRef50_B0BZ78 Nucleotidyl transferase protein n=5 Tax=Cyanobac...   258   2e-67
UniRef50_A9A224 Nucleotidyl transferase n=3 Tax=Thaumarchaeota R...   258   2e-67
UniRef50_A4YHT6 Glucose-1-phosphate thymidyltransferase n=1 Tax=...   256   5e-67
UniRef50_B0R8I5 Sugar nucleotidyltransferase n=2 Tax=Halobacteri...   256   7e-67
UniRef50_P08075 Glucose-1-phosphate thymidylyltransferase n=49 T...   256   7e-67
UniRef50_Q97EQ2 Nucleoside-diphosphate-sugar pyrophosphorylase n...   256   8e-67
UniRef50_UPI000197A125 nucleotidyl transferase n=1 Tax=Helicobac...   255   1e-66
UniRef50_Q1J1J1 Glucose-1-phosphate thymidyltransferase n=10 Tax...   255   2e-66
UniRef50_A8GZ91 Nucleotidyl transferase n=5 Tax=Gammaproteobacte...   254   3e-66
UniRef50_B6BGD8 Nucleotidyl transferase n=1 Tax=Campylobacterale...   253   6e-66
UniRef50_Q2WB86 Nucleoside-diphosphate-sugar pyrophosphorylase n...   253   7e-66
UniRef50_C7LY80 Nucleotidyl transferase n=1 Tax=Acidimicrobium f...   253   8e-66
UniRef50_A0B7L5 Nucleotidyl transferase n=1 Tax=Methanosaeta the...   252   9e-66
UniRef50_Q23RS7 Nucleotidyl transferase family protein n=3 Tax=E...   252   9e-66
UniRef50_Q1Q6W7 Putative uncharacterized protein n=2 Tax=Bacteri...   252   1e-65
UniRef50_C8SCM3 Nucleotidyl transferase n=1 Tax=Ferroglobus plac...   252   1e-65
UniRef50_A6UUQ4 Glucosamine-1-phosphate N-acetyltransferase n=6 ...   252   1e-65
UniRef50_D2RY68 Nucleotidyl transferase n=2 Tax=Halobacteriaceae...   251   2e-65
UniRef50_Q2LPS3 Glucose-1-phosphate adenylyltransferase n=3 Tax=...   251   2e-65
UniRef50_B5GDG2 Nucleotide phosphorylase n=1 Tax=Streptomyces sp...   251   2e-65
UniRef50_UPI0001C16C8D Mannose-1-phosphate guanyltransferase CBS...   251   3e-65
UniRef50_B1BCE9 Nucleotidyl transferase n=2 Tax=Clostridium RepI...   250   4e-65
UniRef50_B8D5T2 Putative sugar-phosphate nucleotidyl transferase...   249   6e-65
UniRef50_C7LVF0 Nucleotidyl transferase n=2 Tax=Proteobacteria R...   249   7e-65
UniRef50_A8G626 Nucleoside-diphosphate-sugar pyrophosphorylase n...   249   1e-64
UniRef50_A7ZFS2 Nucleotidyl transferase n=3 Tax=Proteobacteria R...   248   1e-64
UniRef50_Q18G10 Glucose-1-phosphate thymidylyltransferase n=5 Ta...   248   1e-64
UniRef50_Q6L165 Mannose-1-phosphate guanyltransferase n=3 Tax=Th...   248   2e-64
UniRef50_C6D3B0 Nucleotidyl transferase n=1 Tax=Paenibacillus sp...   248   2e-64
UniRef50_C5VTI3 Nucleotidyl transferase n=1 Tax=Clostridium botu...   247   3e-64
UniRef50_Q1AVJ3 Nucleotidyl transferase n=1 Tax=Rubrobacter xyla...   247   4e-64
UniRef50_Q8YRP4 Mannose-1-phosphate guanyltransferase n=11 Tax=B...   246   5e-64
UniRef50_UPI000038E164 mannose-1-phosphate guanyltransferase n=1...   246   5e-64
UniRef50_Q5CTS3 Mannose-1-phosphate guanylyltransferase n=2 Tax=...   246   7e-64
UniRef50_B1HN58 Mannose-1-phosphate guanyltransferase 2 n=5 Tax=...   246   8e-64
UniRef50_A9CZR8 Nucleotidyl transferase n=1 Tax=Hoeflea phototro...   246   9e-64
UniRef50_UPI0001C315B1 Nucleotidyl transferase n=1 Tax=Conexibac...   246   1e-63
UniRef50_A0ADR0 Putative nucleoside-diphosphate-sugar pyrophosph...   245   1e-63
UniRef50_Q3Z925 Glucose-1-phosphate thymidylyltransferase n=5 Ta...   245   1e-63
UniRef50_A9A1Q3 Glucose-1-phosphate thymidyltransferase n=1 Tax=...   244   2e-63
UniRef50_Q4UEZ4 GDP-mannose pyrophosphorylase, putative n=2 Tax=...   244   2e-63
UniRef50_Q3SPZ3 Nucleotidyl transferase n=1 Tax=Nitrobacter wino...   244   2e-63
UniRef50_A0L542 Nucleotidyl transferase n=2 Tax=Proteobacteria R...   244   2e-63
UniRef50_Q2FRV9 Nucleotidyl transferase n=7 Tax=cellular organis...   244   3e-63
UniRef50_B9LMT7 Nucleotidyl transferase n=2 Tax=Halobacteriaceae...   244   3e-63
UniRef50_B9LW43 Nucleotidyl transferase n=5 Tax=Halobacteriaceae...   244   3e-63
UniRef50_B1XM99 Sugar-phosphate nucleotidyl transferase n=59 Tax...   244   3e-63
UniRef50_D2EEI5 Nucleotidyl transferase n=1 Tax=Candidatus Parva...   244   3e-63
UniRef50_C4SU82 Nucleoside-diphosphate-sugar pyrophosphorylase i...   243   6e-63
UniRef50_B0BLL5 dTDP-1-glucose synthase n=1 Tax=Actinomadura mad...   243   7e-63
UniRef50_C0G2T6 Nucleotidyl transferase n=1 Tax=Natrialba magadi...   243   8e-63
UniRef50_UPI0001693120 glucose-1-phosphate thymidyltransferase n...   243   8e-63
UniRef50_B5HPZ4 Nucleotide phosphorylase n=1 Tax=Streptomyces sv...   242   9e-63
UniRef50_B7XJS8 Mannose-1-phosphate guanyltransferase n=1 Tax=En...   242   9e-63
UniRef50_Q5HT82 Nucleotidyltransferase family protein n=11 Tax=C...   242   9e-63
UniRef50_P39629 Spore coat polysaccharide biosynthesis protein s...   242   1e-62
UniRef50_D0RRF5 Glucose-1-phosphate thymidylyltransferase (DTDP-...   241   2e-62
UniRef50_Q6MME9 Mannose-1-phosphate guanyltransferase n=1 Tax=Bd...   241   2e-62
UniRef50_A9B2A2 Nucleotidyl transferase n=1 Tax=Herpetosiphon au...   241   3e-62
UniRef50_B9CMC2 Glucose-1-phosphate adenylyltransferase n=1 Tax=...   240   5e-62
UniRef50_C5ELG1 HAD-superfamily protein n=2 Tax=Clostridiales Re...   240   6e-62
UniRef50_Q01T68 Nucleotidyl transferase n=8 Tax=cellular organis...   239   6e-62
UniRef50_A2C5W2 Nucleoside-diphosphate-sugar pyrophosphorylase n...   239   6e-62
UniRef50_A8RPP5 Putative uncharacterized protein n=2 Tax=Clostri...   239   6e-62
UniRef50_C2KXR6 Glucose-1-phosphate cytidylyltransferase n=1 Tax...   239   6e-62
UniRef50_Q3AQC4 Glucose-1-phosphate thymidylyltransferase n=12 T...   239   8e-62
UniRef50_Q31FM5 Nucleotidyl transferase n=1 Tax=Thiomicrospira c...   239   8e-62
UniRef50_A3DMT9 Nucleotidyl transferase n=11 Tax=Thermoprotei Re...   239   1e-61
UniRef50_A7NP68 Nucleotidyl transferase n=2 Tax=Roseiflexus RepI...   238   1e-61
UniRef50_B4SDB4 Nucleotidyl transferase n=1 Tax=Pelodictyon phae...   238   2e-61
UniRef50_B9KYJ6 Glucose-1-phosphate thymidylyltransferase n=5 Ta...   238   2e-61
UniRef50_D0KYG3 Nucleotidyl transferase n=30 Tax=cellular organi...   238   2e-61
UniRef50_A9W818 Nucleotidyl transferase n=2 Tax=Rhizobiales RepI...   238   2e-61
UniRef50_A8FIL3 Spore coat polysaccharide biosynthesis protein S...   238   2e-61
UniRef50_D2LMS4 Nucleotidyl transferase n=3 Tax=Aciduliprofundum...   238   3e-61
UniRef50_A8LZU8 Glucose-1-phosphate thymidyltransferase n=15 Tax...   237   3e-61
UniRef50_C9LPM2 Nucleotidyl transferase family enzyme n=1 Tax=Di...   237   4e-61
UniRef50_Q0G1T6 Nucleotidyl transferase n=1 Tax=Fulvimarina pela...   237   4e-61
UniRef50_Q26CD7 Putative nucleoside diphosphate sugar pyrophosph...   237   4e-61
UniRef50_A6C2H5 Nucleoside-diphosphate-sugar pyrophosphorylase n...   237   4e-61
UniRef50_C7P380 Nucleotidyl transferase n=20 Tax=Halobacteriacea...   236   6e-61
UniRef50_B0VGT1 Putative Mannose-1-phosphate guanylyltransferase...   235   1e-60
UniRef50_Q7U909 Putative sugar-phosphate nucleotide transferase ...   235   1e-60
UniRef50_B0THI4 D,d-heptose 1,7-bisphosphate phosphatase subfami...   235   2e-60
UniRef50_D1PXL9 Mannose-1-phosphate guanyltransferase n=2 Tax=Ba...   234   2e-60
UniRef50_A7GGU6 Nucleotidyl transferase family protein n=4 Tax=C...   234   2e-60
UniRef50_A8MDH4 Nucleotidyl transferase n=6 Tax=Thermoproteaceae...   234   2e-60
UniRef50_Q036S8 Glucose-1-phosphate adenylyltransferase n=9 Tax=...   234   2e-60
UniRef50_Q0W734 Nucleotidyltransferase family protein n=2 Tax=Eu...   234   3e-60
UniRef50_Q28JE9 Nucleotidyl transferase n=1 Tax=Jannaschia sp. C...   234   3e-60
UniRef50_B8D6C9 Glucose-1-phosphate thymidylyltransferase n=1 Ta...   234   4e-60
UniRef50_A4BEN1 Nucleoside-diphosphate-sugar pyrophosphorylase n...   233   4e-60
UniRef50_C5A4I2 Sugar-phosphate nucleotydyltransferase n=9 Tax=T...   233   5e-60
UniRef50_A1WSE0 Nucleotidyl transferase n=1 Tax=Verminephrobacte...   233   6e-60
UniRef50_A8MC98 Nucleotidyl transferase n=1 Tax=Caldivirga maqui...   233   7e-60
UniRef50_B8IAD4 Nucleotidyl transferase n=1 Tax=Methylobacterium...   233   7e-60
UniRef50_C4PX01 Gdp-mannose pyrophosphorylase b, isoform 2 n=1 T...   233   8e-60
UniRef50_C7NV90 Nucleotidyl transferase n=1 Tax=Halorhabdus utah...   233   9e-60
UniRef50_B5EDT7 Nucleotidyl transferase n=5 Tax=Bacteria RepID=B...   232   1e-59
UniRef50_Q3K1K4 Glucose-1-phosphate adenylyltransferase n=14 Tax...   232   1e-59
UniRef50_A3DNE2 Nucleotidyl transferase n=8 Tax=Thermoprotei Rep...   232   1e-59
UniRef50_Q7X521 PtmE n=1 Tax=Campylobacter coli RepID=Q7X521_CAMCO    231   2e-59
UniRef50_C2D9Q4 Glucose-1-phosphate adenylyltransferase n=1 Tax=...   230   3e-59
UniRef50_A3WUE7 Nucleoside-diphosphate-sugar pyrophosphorylase n...   230   4e-59
UniRef50_A9VB22 Predicted protein n=1 Tax=Monosiga brevicollis R...   230   4e-59
UniRef50_B5ZR76 Nucleotidyl transferase n=12 Tax=Bacteria RepID=...   230   5e-59
UniRef50_Q5UXR9 Glucose-1-phosphate thymidylyltransferase n=2 Ta...   230   5e-59
UniRef50_C4XP25 Nucleotidyl transferase domain protein n=3 Tax=P...   230   5e-59
UniRef50_A6TK87 UTP-glucose-1-phosphate uridylyltransferase n=5 ...   229   8e-59
UniRef50_C7NR86 Nucleotidyl transferase n=4 Tax=Halobacteriaceae...   229   8e-59
UniRef50_A3CRY9 UDP-glucose pyrophosphorylase n=2 Tax=Methanomic...   229   1e-58
UniRef50_Q49VP4 UTP--glucose-1-phosphate uridylyltransferase 2 n...   229   1e-58
UniRef50_B8FX62 Glucose-1-phosphate adenylyltransferase n=2 Tax=...   229   1e-58
UniRef50_C2G0W6 Nucleotidyl transferase n=1 Tax=Sphingobacterium...   228   1e-58
UniRef50_A9FF13 Putative sugar-phosphate nucleotide transferase ...   228   1e-58
UniRef50_C9XS92 Utp--glucose-1-phosphate uridylyltransferase (Ge...   228   2e-58
UniRef50_D0XT48 Nucleotidyl transferase n=1 Tax=Brevundimonas su...   228   2e-58
UniRef50_UPI000197319A nucleoside-diphosphate-sugar pyrophosphor...   228   2e-58
UniRef50_B7KYN3 Nucleotidyl transferase n=1 Tax=Methylobacterium...   228   2e-58
UniRef50_A9BBF8 Nucleoside-diphosphate-sugar pyrophosphorylase n...   228   3e-58
UniRef50_Q7MEE9 Glucose-1-phosphate adenylyltransferase 2 n=58 T...   228   3e-58
UniRef50_Q0W805 Putative glucose-1-phosphate thymidylyltransfera...   227   4e-58
UniRef50_Q9YCT0 Glucose-1-phosphate thymidylyltransferase n=1 Ta...   227   4e-58
UniRef50_C8PNH3 Nucleotidyl transferase n=6 Tax=Bacteria RepID=C...   227   4e-58
UniRef50_C1XRH9 Histidinol-phosphate phosphatase family protein ...   226   6e-58
UniRef50_Q54800 UTP--glucose-1-phosphate uridylyltransferase n=1...   226   6e-58
UniRef50_A4GI83 Mannose-1-phosphate guanyltransferase n=1 Tax=un...   226   8e-58
UniRef50_D2PFA0 Nucleotidyl transferase n=10 Tax=Sulfolobus RepI...   226   1e-57
UniRef50_A1VGN4 Nucleotidyl transferase n=1 Tax=Desulfovibrio vu...   226   1e-57
UniRef50_Q8CUH8 Spore coat polysaccharide synthesis (Glucose-1-p...   225   1e-57
UniRef50_B9L1J9 Glucose-1-phosphate adenylyltransferase n=15 Tax...   225   1e-57
UniRef50_Q8TWW4 Nucleoside-diphosphate-sugar pyrophosphorylase i...   225   2e-57
UniRef50_Q89HJ6 Blr5994 protein n=1 Tax=Bradyrhizobium japonicum...   225   2e-57
UniRef50_B3PKU9 Nucleotidyltransferase family protein n=1 Tax=Ce...   225   2e-57
UniRef50_C7PPE5 Nucleotidyl transferase n=1 Tax=Chitinophaga pin...   224   3e-57
UniRef50_Q1J1Y9 Nucleotidyl transferase n=2 Tax=Deinococcus RepI...   224   3e-57
UniRef50_B6AEL1 Nucleotidyl transferase family protein n=1 Tax=C...   224   3e-57
UniRef50_B2VWC7 Mannose-1-phosphate guanyltransferase n=2 Tax=Le...   224   3e-57
UniRef50_A4WLA7 Nucleotidyl transferase n=6 Tax=Thermoproteaceae...   224   3e-57
UniRef50_A6CVH6 Glucose-1-phosphate adenylyltransferase n=1 Tax=...   224   3e-57
UniRef50_C6CVH3 Nucleotidyl transferase n=3 Tax=Bacillales RepID...   224   4e-57
UniRef50_A2U039 Nucleotidyl transferase n=1 Tax=Polaribacter sp....   223   7e-57
UniRef50_C6VS96 Nucleotidyl transferase n=1 Tax=Dyadobacter ferm...   222   7e-57
UniRef50_A3DK82 Glucose-1-phosphate adenylyltransferase n=73 Tax...   222   1e-56
UniRef50_D2RP80 Nucleotidyl transferase n=2 Tax=Haloterrigena tu...   222   1e-56
UniRef50_A4XFV3 Nucleotidyl transferase n=1 Tax=Caldicellulosiru...   221   2e-56
UniRef50_Q9L385 Glucose-1-phosphate adenylyltransferase n=19 Tax...   221   2e-56
UniRef50_A3DKS4 Nucleotidyl transferase n=1 Tax=Staphylothermus ...   221   3e-56
UniRef50_D1C4F4 Nucleotidyl transferase n=1 Tax=Sphaerobacter th...   221   3e-56
UniRef50_A1RYE8 Nucleotidyl transferase n=1 Tax=Thermofilum pend...   221   3e-56
UniRef50_A7VCP9 Putative uncharacterized protein n=5 Tax=Bacteri...   221   3e-56
UniRef50_A8A970 Nucleotidyl transferase n=1 Tax=Ignicoccus hospi...   220   4e-56
UniRef50_C5A4G3 Sugar-phosphate nucleotydyltransferase n=9 Tax=A...   220   4e-56
UniRef50_Q9X3S7 Glucose-1-phosphate thymidyl transferase n=1 Tax...   220   4e-56
UniRef50_P37820 Putative mannose-1-phosphate guanyltransferase n...   220   4e-56
UniRef50_B3T1I2 Putative Nucleotidyl transferase n=1 Tax=uncultu...   220   5e-56
UniRef50_C7PVA0 Nucleotidyl transferase n=3 Tax=Bacteroidetes Re...   219   7e-56
UniRef50_Q30U75 Nucleotidyl transferase n=3 Tax=Proteobacteria R...   219   7e-56
UniRef50_B1QX92 Nucleotidyl transferase n=3 Tax=Clostridiales Re...   219   7e-56
UniRef50_Q1J021 Glucose-1-phosphate adenylyltransferase n=5 Tax=...   219   7e-56
UniRef50_Q01PZ9 UDP-glucose pyrophosphorylase n=1 Tax=Candidatus...   219   8e-56
UniRef50_A9H8Q9 Nucleoside-diphosphate-sugar pyrophosphorylase n...   219   1e-55

Sequences not found previously or not previously below threshold:

>UniRef50_A3DED2 Nucleotidyl transferase n=8 Tax=Clostridium RepID=A3DED2_CLOTH
          Length = 820

 Score =  317 bits (813), Expect = 3e-85,   Method: Composition-based stats.
 Identities = 66/278 (23%), Positives = 115/278 (41%), Gaps = 14/278 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +I+AGG GTRL P+T    K ++P+ +KP++ + + +L   G  +I +         
Sbjct: 1   MKAVIMAGGEGTRLRPLTCNRPKPMVPVVNKPVMEHIIELLKKHGFTDIAVTLQY-LPDM 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDGS+FGI L Y  +  P G A +    E FL  + + LV+  +          +
Sbjct: 60  IKDYFGDGSDFGINLRYYVEDKPMGTAGSVKNAEEFL--DDTFLVISGDALTDIDLGKAV 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
            +  ++   AT+   +V  P  +GVV  D+N R     EKP   +  S+   TG+Y    
Sbjct: 118 EYHYSKGSMATLVLKKVDIPLEYGVVVTDENGRITRFLEKPSWGEVFSDTVNTGIYILSP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +V++Y  + +  +        +  M L+        +     W D G   +  +A   V 
Sbjct: 178 EVLKYFNKNEMFD----FSKDLFPMLLKENKPMYGYITDE-YWCDIGDLMAYSKAHMDVL 232

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKT 276
             +     KI           W+ +  V      + + 
Sbjct: 233 DGK----VKINIPGNKIKDRVWVGEGTVIEENVVIEEP 266


>UniRef50_A4J6Z1 Nucleotidyl transferase n=3 Tax=Peptococcaceae RepID=A4J6Z1_DESRM
          Length = 828

 Score =  307 bits (787), Expect = 3e-82,   Method: Composition-based stats.
 Identities = 63/296 (21%), Positives = 120/296 (40%), Gaps = 15/296 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK II+AGG GTRL P+T G+ K ++P+ ++PM+ + L +L   G+ +I +      +  
Sbjct: 7   MKAIIMAGGEGTRLRPLTCGLPKPMMPVCNRPMMEHILHLLKKHGVHDIGVTLQYLPEA- 65

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   G+G++F + + Y  +  P G A +    + FL  + + +V+  +       S  L
Sbjct: 66  IRGYFGNGADFNVHMRYYVEEVPLGTAGSVKNAQKFL--DETFIVISGDALTDLDLSQAL 123

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDS 178
                +   AT+    V  P  +GVV  + +       EKP   +  S+   TG+Y  + 
Sbjct: 124 EFHRKKGAIATLVLTPVDIPLEYGVVITNGDGHITQFLEKPGWGEVFSDTVNTGIYILEP 183

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +V+ Y +  +  +        +  + L+       +      W D G     ++A     
Sbjct: 184 EVLNYFEPGQKFD----FSNDLFPILLKEKQPLFGV-SLSGYWCDIGNLQQYVQAHQDCL 238

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY-GQYLLELLRARPRQY 293
           T +      ++   E      W+ +    +A + +      GQ       A    Y
Sbjct: 239 TGK----VSVSIPGEQVAPGVWVGENTQIQAGAKIIGPALIGQNCKIGAAAVLGTY 290


>UniRef50_D2AV47 Phosphoglucomutase/phosphomannomutase family protein n=27
           Tax=Bacteria RepID=D2AV47_STRRD
          Length = 828

 Score =  306 bits (784), Expect = 8e-82,   Method: Composition-based stats.
 Identities = 71/291 (24%), Positives = 115/291 (39%), Gaps = 14/291 (4%)

Query: 6   LAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQRLL 65
           +AGG GTRL P+T    K LLP+ ++P++ + L +L   G+ E ++          +   
Sbjct: 1   MAGGEGTRLRPMTANQPKPLLPVINRPIMEHVLRLLRRHGLTETVVTVQF-LAALVRNYF 59

Query: 66  GDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHVAA 125
           GDG E G+ L YA + +P G A +       L  +   LV+  +       +  +R    
Sbjct: 60  GDGDELGMSLYYATEDTPLGTAGSVKNAADKLRDDR-FLVISGDALTDIDLTDMIRFHRE 118

Query: 126 RTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDSKVVEY 183
                T+   +V +P  FG+V  DD+ R     EKP   Q  S+   TG+Y  + +V++ 
Sbjct: 119 NGALVTIGLKRVPNPLEFGIVIVDDHGRVERFLEKPTWGQVFSDTVNTGIYVMEPEVLDE 178

Query: 184 AKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEKR 243
                P +        +    L  G      +     W D GTH+S + A   V +   R
Sbjct: 179 IAAGVPVDW----SADVFPRLLARGAPLYGYVA-EGYWEDVGTHESYLRAQADVLSGRVR 233

Query: 244 QGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY-GQYLLELLRARPRQY 293
               +           W+ +       + L    Y G Y      A  R+Y
Sbjct: 234 ----VDTDAFEVSPGVWVAEGASVDTDAVLKGPLYIGDYAKVEAGAELREY 280


>UniRef50_C8W233 Nucleotidyl transferase n=1 Tax=Desulfotomaculum acetoxidans DSM
           771 RepID=C8W233_DESAS
          Length = 830

 Score =  305 bits (783), Expect = 1e-81,   Method: Composition-based stats.
 Identities = 64/280 (22%), Positives = 119/280 (42%), Gaps = 14/280 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK II+AGG G+RL P+T G  K ++P+ +KP++ + + +L   GI +I +      +  
Sbjct: 3   MKAIIMAGGEGSRLRPLTCGRPKPMVPVLNKPVMCHIIDLLKQHGITDIGVTLQYMPEA- 61

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   G GS+FG+ + Y  + SP G A +      FL  + + LV+  +       S  +
Sbjct: 62  IKDYFGSGSQFGVNISYFVEESPLGTAGSVKNAGNFL--DETFLVISGDALTDLNLSKAI 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
                +   AT+   +V  P  +GVV  ++N R     EKP   +  S+   TG+Y  + 
Sbjct: 120 EFHRNQCSDATILLTRVDCPLEYGVVITEENGRIRRFLEKPSWGEVFSDTVNTGIYILEP 179

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
            V++Y  Q +  +        +    L+       L+ +   W D G     ++A     
Sbjct: 180 GVLDYFNQGQVFD----FSKDLFPRLLKDKKPLFGLVQQ-GYWCDIGNLRQYLQAHYDAL 234

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
           + +     KI+   +   +  W+    +   +  +     
Sbjct: 235 SGK----VKISIPGKEIAQGVWVGKGALISDSVEMEGPLL 270


>UniRef50_UPI0001C42A13 Nucleoside-diphosphate-sugar pyrophosphorylase fused to
           phosphomannomutase n=1 Tax=Bacillus pseudofirmus OF4
           RepID=UPI0001C42A13
          Length = 808

 Score =  305 bits (782), Expect = 1e-81,   Method: Composition-based stats.
 Identities = 69/296 (23%), Positives = 116/296 (39%), Gaps = 15/296 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+I+AGG GTRL P+T  + K ++P+  KP++ Y + +L   GI +I +         
Sbjct: 1   MKGVIMAGGKGTRLRPLTCQLPKPMVPLLQKPVMQYSIELLKQHGITDIAVTVHYLPDE- 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDG EFG+ L Y E+  P G A +    E FL  +   +V+  +          +
Sbjct: 60  IRDYFGDGQEFGVHLTYFEETEPLGTAGSVKQAEAFL--DEPFVVVSGDALTDFDLEAGI 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDS 178
               A+    ++F  QV  P  FGV+  +     I   EKP   +  S+   TG+Y  D 
Sbjct: 118 NFHKAKDALVSIFMKQVPCPLEFGVIMTNQQHEIIRFLEKPSVSEVFSDTVNTGIYVMDP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
            +  Y +  KP +        +    LE              W D G  +   +A   + 
Sbjct: 178 SIFNYIESDKPVD----FSKDVFPRILEDRAGIYGY-AAEGYWSDIGNLEQYRQAHMDLL 232

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY-GQYLLELLRARPRQY 293
             + +       +E       W+++         L    + G +      A+   +
Sbjct: 233 NRDVKAEISGIEVE----PGIWMNEHVTIEEGVKLEAPVFVGAHSTVRSNAKLGAF 284


>UniRef50_P55253 Glucose-1-phosphate thymidylyltransferase n=1508 Tax=cellular
           organisms RepID=RMLA3_ECOLX
          Length = 293

 Score =  305 bits (781), Expect = 2e-81,   Method: Composition-based stats.
 Identities = 189/288 (65%), Positives = 230/288 (79%), Gaps = 1/288 (0%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           KGIILAGGSGTRL+P+T  VSKQLLPIYDKPMIYYPLS LMLAGIR+ILII+TP+D   F
Sbjct: 5   KGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPRF 64

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLR 121
           Q+LLGDGS++G+ L+Y  QPSPDGLAQAFIIGE F+ G+   LVLGDNIF+G      + 
Sbjct: 65  QQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEDFIGGDDCALVLGDNIFYGHDLPKLME 124

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVV 181
               +  GATVF Y V DPER+GVVEFD+N  AISLEEKP +PKSN+AVTGLYFYD+ VV
Sbjct: 125 AAVNKESGATVFAYHVNDPERYGVVEFDNNGTAISLEEKPLEPKSNYAVTGLYFYDNDVV 184

Query: 182 EYAKQV-KPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           E A++  KPS RGELEIT IN++Y+E G L+V ++GRG+AWLDTGTH SLIEAS F+ T+
Sbjct: 185 EMARKNLKPSARGELEITDINRIYMEQGRLSVAMMGRGYAWLDTGTHQSLIEASNFIATI 244

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRA 288
           E+RQG K++C EEIA+R G++D E VK  A  L K  YGQYLL++++ 
Sbjct: 245 EERQGLKVSCPEEIAYRKGFIDAEQVKVLAEPLKKNAYGQYLLKMIKG 292


>UniRef50_A8KY05 Nucleotidyl transferase n=6 Tax=Actinomycetales RepID=A8KY05_FRASN
          Length = 843

 Score =  305 bits (781), Expect = 2e-81,   Method: Composition-based stats.
 Identities = 69/296 (23%), Positives = 119/296 (40%), Gaps = 14/296 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +++AGG GTRL P+T  + K LLP+ ++P++ + L +L   G  E ++         
Sbjct: 1   MRAVVMAGGEGTRLRPLTANLPKPLLPVVNRPIMEHVLRLLKRHGFDETVVTVQF-LAAM 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   G G E G+ L YA + +P G A +    E  L  E   LV+  +       +  +
Sbjct: 60  IRNYFGSGDELGMHLSYATETTPLGTAGSVKNAEDALRHEE-FLVISGDALTDIDLTDLV 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
            +  A+    TV    V DP  FG+V   ++ R     EKP   Q  S+   TG+Y  + 
Sbjct: 119 AYHRAQGALVTVALKSVPDPLEFGIVITGEDGRISRFLEKPTWGQVFSDTVNTGIYVMEP 178

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +V+++    +  +        +    + AG      +  G  W D GT  S   A   V 
Sbjct: 179 EVLDHVPAGEAVDW----SGDVFPRLVAAGAPVFGYVA-GGYWEDVGTIASFQRAQADVL 233

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKT-GYGQYLLELLRARPRQY 293
             +      ++          W+ ++      + L      G Y      A  R++
Sbjct: 234 NRQ----VDVSIGGFEVSPGVWIGEDADVHPDAILKGPLVVGDYSKVEAGAELREF 285


>UniRef50_C0GEN7 Nucleotidyl transferase n=1 Tax=Dethiobacter alkaliphilus AHT 1
           RepID=C0GEN7_9FIRM
          Length = 824

 Score =  302 bits (774), Expect = 1e-80,   Method: Composition-based stats.
 Identities = 61/280 (21%), Positives = 115/280 (41%), Gaps = 14/280 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK II+AGG G+RL P+T    K ++PI ++PM+ + +S+L    ++EI +         
Sbjct: 1   MKAIIMAGGQGSRLRPLTCDRPKPMVPIMNRPMMEHIVSLLKSYDLKEIGVTLQY-LPEQ 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDG EFG+ + Y  + SP G A +     +FL  + + +V+  +          +
Sbjct: 60  IENYFGDGREFGVNMRYFIEDSPLGTAGSVKNSGSFL--DETFIVISGDALTDFDLQKAI 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
               A+   AT+    V  P  +GVV  +D  R     EKP   +  S+   TG+Y  + 
Sbjct: 118 EFHRAKGGVATLVLTSVETPLEYGVVIANDEGRITQFLEKPSWGEVFSDTVNTGIYILEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +V++Y  +    +        +  + ++ G      +     W D G  +    A   + 
Sbjct: 178 EVLQYVPEGAQFDFA----KDLFPLLMQKGYPLYGYVA-EGYWCDIGNIEQYHGAHLDIL 232

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
               +   K+   E       ++ +  +    + +     
Sbjct: 233 ----KDTVKVNIQEREQSPGVYVGENVIIEPGAQINAPAL 268


>UniRef50_A9B3S0 Nucleotidyl transferase n=6 Tax=Chloroflexi (class)
           RepID=A9B3S0_HERA2
          Length = 835

 Score =  301 bits (771), Expect = 2e-80,   Method: Composition-based stats.
 Identities = 64/294 (21%), Positives = 117/294 (39%), Gaps = 19/294 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +++AGG G+RL P+T    K ++P+ D+P++ + + +L   GI +I+I         
Sbjct: 1   MKAVLMAGGEGSRLRPLTISRPKPMVPLVDRPVMGHIIELLKRHGITDIIITVQY-LANI 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGE-PSCLVLGDNIFFGQGFSPK 119
            Q   GDGS F + + Y+ +  P G A A       ++ +    LV+  +       +  
Sbjct: 60  IQDFYGDGSAFDVDISYSVEEVPLGTAGAVKYASRLIDDDSEPILVISGDALTDFDLTAL 119

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYD 177
           +         AT+   +V +P  +GVV  DD  R     EKP   +  S+   TG+Y  D
Sbjct: 120 IEAHKRSNAKATITLTRVPNPLEYGVVITDDTGRIRQFLEKPSWGEVFSDTVNTGIYVID 179

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
             V++     +P +        +    L  G L    +     W D G  ++ + A +  
Sbjct: 180 PCVLDDIPLGEPFD----FSKDLFPALLRRGELLHGYIA-EGYWTDVGNIEAYMRACSDY 234

Query: 238 QTVE---KRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRA 288
                   R G            N W++ E      + +    +  + +++   
Sbjct: 235 LMGMVNLPRLGHD-------RGDNVWIEGEVEIAPDAQIHGPVFFGHGVKIKGG 281


>UniRef50_C0ZG53 Probable mannose-1-phosphate guanyltransferase n=1
           Tax=Brevibacillus brevis NBRC 100599 RepID=C0ZG53_BREBN
          Length = 801

 Score =  300 bits (770), Expect = 3e-80,   Method: Composition-based stats.
 Identities = 73/280 (26%), Positives = 119/280 (42%), Gaps = 14/280 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +I+AGG GTRL P+T    K ++P+ ++P + Y + +L   GI EI +         
Sbjct: 1   MKAVIMAGGKGTRLRPLTCHTPKPMVPLLNRPCMEYTIDLLKKHGITEIAVTLQY-LPDV 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDGS +G+ L Y E+  P G A +      FL  +   +V+  +       S  +
Sbjct: 60  IRDTFGDGSRYGVSLVYFEEAIPLGTAGSVKNCADFL--DERFVVISGDTLTDIDLSAAI 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
           R        AT+   +V  P  FGVV  D+  R     EKP   +  S+   TG+Y  + 
Sbjct: 118 RFHEQNNALATLILTRVETPLEFGVVMTDEGGRITRFLEKPSWAEVFSDTVNTGIYVCEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +V+ Y ++    ER       I   +L+A             W D G+ +   +A   + 
Sbjct: 178 EVLSYIEE----EREVDFSKEIFPSFLQAAKPLYGY-EASGYWSDIGSLEVYQQAQFDLL 232

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
                   K    +EIA R  +L+++    ++  L    Y
Sbjct: 233 DGRVHLEIK---AQEIAPR-IFLENDVRIDSSVRLEGPVY 268


>UniRef50_A5N939 Predicted glucose-1-phosphate nucleotidyltransferase containing an
           additional conserved domain n=5 Tax=Clostridium
           RepID=A5N939_CLOK5
          Length = 814

 Score =  300 bits (769), Expect = 4e-80,   Method: Composition-based stats.
 Identities = 64/280 (22%), Positives = 116/280 (41%), Gaps = 14/280 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +I+AGG GTRL P+T  + K ++P+  KP++ Y L +L   GI +I           
Sbjct: 1   MKAVIMAGGEGTRLRPLTCNIPKPMMPVMGKPIMEYALELLKNTGIEDIGATLQYLPDEI 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                GDG +FG+ + Y  + +P G A +    E FLN   + +V+  +       S  +
Sbjct: 61  I-NYFGDGRDFGVNISYFVEETPLGTAGSVKNAEAFLND--TFIVISGDALTDIDLSRAI 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDS 178
            +  ++   AT+   +   P  FGVV  DD  +     EKP   +  S+   TG+Y  + 
Sbjct: 118 SYHKSKGAVATLVLKEEPVPLEFGVVVTDDKGKVTGFLEKPGWGEVFSDKVNTGIYILEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           ++ +Y  + K  +      + +  + L+        +     W D G  D  ++    + 
Sbjct: 178 EIFKYYGKNKKCD----FSSELFPLLLKEKAAVFGYVA-EGYWCDIGNIDQYMKCHFDIL 232

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
                   K     E    + W+ ++      + ++   Y
Sbjct: 233 KGFANVNIKAQKYSE----DIWIGEDCEISPQAKISTPVY 268


>UniRef50_Q5DIE4 Glucose-1-phosphate thymidylyltransferase n=109 Tax=Bacteria
           RepID=Q5DIE4_ECOLX
          Length = 290

 Score =  299 bits (766), Expect = 1e-79,   Method: Composition-based stats.
 Identities = 216/288 (75%), Positives = 240/288 (83%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPM+YYP+SVLMLAGIR+IL+ITTPED   
Sbjct: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMVYYPMSVLMLAGIRDILLITTPEDLPS 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F+RLLGDGS FGI L Y  Q SPDGL QAFIIGE F+  +   LVLGDNIFFGQ F  KL
Sbjct: 61  FKRLLGDGSRFGINLSYEIQQSPDGLVQAFIIGEEFIADDKCALVLGDNIFFGQSFGRKL 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
             V +   GATVFGYQVMDPERFGVVEFD NF+A+S+EEKP  PKSNWAVTGLYFYD  V
Sbjct: 121 ESVVSGNAGATVFGYQVMDPERFGVVEFDKNFKALSIEEKPAAPKSNWAVTGLYFYDENV 180

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           V+ AK VKPS RGELEIT++N+MYLE GNL VELLGRGFAWLDTGTHDSLIEAS F+ T+
Sbjct: 181 VDMAKCVKPSARGELEITTLNEMYLEQGNLQVELLGRGFAWLDTGTHDSLIEASQFIHTI 240

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRA 288
           EKRQGFKIACLEEIA+RNGWL +  V    + ++KT YGQYLL L++ 
Sbjct: 241 EKRQGFKIACLEEIAYRNGWLTESEVVTYGNEMSKTNYGQYLLNLIKN 288


>UniRef50_Q6MF02 Glucose-1-phosphate thymidylyltransferase n=3 Tax=Bacteria
           RepID=Q6MF02_PARUW
          Length = 295

 Score =  297 bits (762), Expect = 3e-79,   Method: Composition-based stats.
 Identities = 169/290 (58%), Positives = 218/290 (75%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKGI+LAGGSGTRLHP+T GV+KQLLP+Y+KPMIYYPLSVL+LA I++ILII+TPED   
Sbjct: 1   MKGIVLAGGSGTRLHPLTLGVTKQLLPVYNKPMIYYPLSVLLLAEIKDILIISTPEDMPV 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F+RLLGDGS  G++  Y  QP P+GLA+AFIIG+ F+  +  CLVLGDNIF+G   S  L
Sbjct: 61  FKRLLGDGSHLGVRFTYEMQPKPNGLAEAFIIGKDFIGKDSVCLVLGDNIFYGSHLSNLL 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           +    + EGAT+FGY+V DPER+GVVEFD   + +S+EEKPK PKS+ AVTGLYFYD++V
Sbjct: 121 KSAKEKKEGATLFGYEVKDPERYGVVEFDGQGKILSIEEKPKIPKSSIAVTGLYFYDNQV 180

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           V+ A  +KPS RGELEIT +NQ YL      V ++GRG+ WLD GT++SL++AS FVQ +
Sbjct: 181 VDIAHGLKPSARGELEITDVNQEYLNRDQACVHVMGRGYTWLDAGTYESLMQASQFVQVI 240

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRARP 290
           E+RQG  IA LEEIA+   ++    +K     L K+ YG+YL+E+    P
Sbjct: 241 EQRQGHCIASLEEIAYNQKFISQAQLKLLGEKLGKSLYGRYLMEIAEKGP 290


>UniRef50_A3DK29 Nucleotidyl transferase n=13 Tax=Clostridia RepID=A3DK29_CLOTH
          Length = 349

 Score =  297 bits (761), Expect = 3e-79,   Method: Composition-based stats.
 Identities = 66/280 (23%), Positives = 121/280 (43%), Gaps = 15/280 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +K + LAGG GTRL PIT  + K ++PI  KP++   +  L   GI E+++ T  +    
Sbjct: 3   VKALFLAGGLGTRLRPITNDLPKPMVPIMGKPLLERNIEKLKSYGIDEVVLSTCYKPHK- 61

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
             +  GDG +FG+++ Y  +  P G A A    E  L+   + LV   +I      +  +
Sbjct: 62  IDKYFGDGKKFGVKISYITEDKPLGTAGAIKNAEELLSD--TFLVFNADILSDIDIANMI 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
           R    +   AT+   +V +P  +GV+E DD+    + +EKP+  + KSN    G+Y ++ 
Sbjct: 120 RFHKEKGALATIAVTKVDNPSAYGVIEHDDDNFITAFKEKPQPHESKSNLINAGVYIFEK 179

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +++ +  +     R          + LE G     +  +   WLD GT    ++    + 
Sbjct: 180 ELLNHIPRG----RAVSIERETYPLLLEKGYKM-AVYNKCGYWLDLGTPGKYLKVHKDIL 234

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
                +G       +      ++        ++ +    Y
Sbjct: 235 -----KGLVPIGNYDFGQNRTYISKSAKIDRSAKIRGPVY 269


>UniRef50_Q46AY8 Glucose-1-phosphate thymidylyltransferase n=4
           Tax=Methanosarcinaceae RepID=Q46AY8_METBF
          Length = 397

 Score =  296 bits (760), Expect = 5e-79,   Method: Composition-based stats.
 Identities = 74/279 (26%), Positives = 133/279 (47%), Gaps = 10/279 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++L  G GTR+ P+T G  K +L + +KP++ + L+  + AGI   + IT    +  
Sbjct: 1   MKAVVLVAGKGTRMEPLTSGCPKVMLQVANKPILEHILNSAIEAGIEGFVFITGY-LEKQ 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDG+++G+ +EY +Q    G A A    + +++G  + LVL  ++         L
Sbjct: 60  IKEYFGDGNKWGVSIEYVQQKEQLGTANAIGCAKGYVDG--TFLVLNGDMLIE---QEDL 114

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           + + +RTE A +   +V +P  FGV+E  +N R + + EKPK P +N A  G+Y +   +
Sbjct: 115 KALVSRTEEAVICVKEVENPADFGVLET-ENNRVVRIIEKPKNPPTNLANAGIYLFRESI 173

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            ++  + K S R E EIT   QM +++G            W+D G    L++A+ ++   
Sbjct: 174 FDFIDRTKASVRNEFEITDSIQMLIDSGTAVGYSPL-EGRWIDIGYPWDLLKANEYLLKG 232

Query: 241 EKRQGFKIACLEEIAWRN-GWLDDEGVKRAASSLAKTGY 278
            K    +         +    +    + R  S +     
Sbjct: 233 LKS-SCEGTVEPNATIKGEVVIGKGTIIRNGSYIEGPVV 270


>UniRef50_B8CYH8 Phosphoglucomutase n=1 Tax=Halothermothrix orenii H 168
           RepID=B8CYH8_HALOH
          Length = 820

 Score =  296 bits (759), Expect = 6e-79,   Method: Composition-based stats.
 Identities = 64/280 (22%), Positives = 115/280 (41%), Gaps = 13/280 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+I+AGG G+RL P+T  + K ++P+ + P++ Y +++L   GI++I + T       
Sbjct: 1   MKGVIMAGGQGSRLRPLTCNLPKPMVPVMNYPVMEYIITLLKNYGIKDIAVTT-YYLPNK 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDGS++G+ L Y  +  P G A +      FL  +   +V+  +          +
Sbjct: 60  IESYFGDGSKWGVNLHYFVEKEPLGTAGSVANARDFL--DEPFMVISGDAITDFDLGEAI 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDS 178
                +   AT+   +V  P  +GVV  D+  R +   EKP   Q  S+   TG+Y  + 
Sbjct: 118 SFHQEKGASATIVLARVKTPLDYGVVITDERGRIVRFLEKPNWGQVFSDTVNTGIYVLEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           ++ +   +             +  + LE        +     W D G+ +  I  +    
Sbjct: 178 EIFDLYDKGI----NFDFSKDLFPLMLEKNWNLYG-ISLKGYWNDIGSLEEYINTNFDFF 232

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
             E     +  C   +   N WL D       + L    +
Sbjct: 233 KGEIDLPLEACC---VLDNNIWLQDGVEIDETAELEGPLF 269


>UniRef50_Q2NES5 Predicted nucleoside-diphosphate-sugar pyrophosphorylase n=10
           Tax=cellular organisms RepID=Q2NES5_METST
          Length = 431

 Score =  295 bits (757), Expect = 9e-79,   Method: Composition-based stats.
 Identities = 74/300 (24%), Positives = 128/300 (42%), Gaps = 16/300 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK IIL  G GTR+ P+T    K +L    KP+I Y +  L  AGI++I ++   + +  
Sbjct: 1   MKAIILTAGEGTRMRPLTTTRPKTMLITGGKPLIQYNIESLRDAGIKDITLVVGYKKE-V 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGF-SPK 119
            +   GDGSE+G+ + YA Q    G A A    E ++  + S +VL  +I          
Sbjct: 60  IEDYFGDGSEYGVNITYAVQEGQLGTAHAIGSAEEYI--DESFIVLNGDIIVSYDLIRNL 117

Query: 120 LRHVA---ARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLY 174
           +   A   +    + +   +V DP  +G+V   +N +   + EKP  +   SN A  G+Y
Sbjct: 118 IEKYATRTSNNVKSVLTLIEVDDPSSYGIVST-ENGKITEIIEKPSVEDAPSNLANAGIY 176

Query: 175 FYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
            +  ++ +  ++ + S+RGE EIT    + L  G   + L+     W+D G    L+E +
Sbjct: 177 LFSPEIFDAIRKTELSKRGEYEITDSLDIELSEGWEILGLISNE-KWMDVGRPWELLECN 235

Query: 235 TFVQTVEKRQGFKIACLEEIAWRNGW-LDDEGVKRAASSLAKTGYGQYLLELLRARPRQY 293
                       +    + +       L    + R+   +    +   + E     P  Y
Sbjct: 236 QDFLEKMDD-SIEGEIEDNVTIHGPVHLGKGSIIRSGCYIQGPVF---IGENCDVGPNTY 291


>UniRef50_Q2RH64 Nucleotidyl transferase n=1 Tax=Moorella thermoacetica ATCC 39073
           RepID=Q2RH64_MOOTA
          Length = 821

 Score =  295 bits (757), Expect = 9e-79,   Method: Composition-based stats.
 Identities = 60/295 (20%), Positives = 113/295 (38%), Gaps = 17/295 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK II+AGG G+RL P+T    K L+P+ ++P++ Y + +L   GI+E+ +         
Sbjct: 1   MKAIIMAGGEGSRLRPLTCKRPKPLVPVANRPVMEYCVDLLRELGIKEVGVTLQY-LPQL 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDGS+FG+ L Y  +  P G A +       L  + + +V+  +        P +
Sbjct: 60  IEEYFGDGSDFGLHLHYFVEDKPLGTAGSVKNAAAIL--DETFVVVSGDALTDFDLRPAI 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
                    AT+    V +P  +GVV  + +    S  EKP   +  S+   TG+Y  + 
Sbjct: 118 ARHKESGALATLVLTAVDNPLEYGVVITNPDGSIRSFLEKPSWGEVFSDRVNTGIYILEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +V+E   + +P +        +    L+       +      W D G      +A   + 
Sbjct: 178 EVLELIPEGRPFD----FSKDLFPRLLKEKRPLYGV-TLSGYWCDIGNLTQYRQAQEDIL 232

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQ---YLLELLRARP 290
                   K+  + +       + +       + +          ++       P
Sbjct: 233 RGR----VKVRVVGQDKGGGVVMGEGVEIAPGARIEGPVLIGGACHIATGAVVGP 283


>UniRef50_UPI0001C418F3 UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate
           N-acetyltransferase GlmU n=1 Tax=Methanobrevibacter
           ruminantium M1 RepID=UPI0001C418F3
          Length = 439

 Score =  295 bits (756), Expect = 1e-78,   Method: Composition-based stats.
 Identities = 83/298 (27%), Positives = 136/298 (45%), Gaps = 15/298 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +IL+ G GTR+ P+T    K +LP+  KP+I Y +  L   G+++IL+I   + +  
Sbjct: 1   MKALILSAGEGTRMRPLTLTKPKTMLPVAGKPIIQYNIEALRECGVKDILLIVGYK-EEM 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQG-FSPK 119
            +    DGS+FG+ + YA Q   +G A A   G+ F+  E S + L  +I   +      
Sbjct: 60  VKNYFDDGSKFGVNISYATQTKLEGTANAISYGKDFI--EDSLITLNGDIILDEEILREI 117

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYD 177
           +           +   +V DP  FGVVE D   +  ++ EKP  ++  SN   TG+Y ++
Sbjct: 118 IEDYEESGADTLMVLTEVEDPSAFGVVELDGE-KITNIVEKPKKEEAPSNLVNTGIYIFN 176

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
             + +   + K S RGE EIT    + +E G            W+D G    LIE +  +
Sbjct: 177 KDIFDKIDKTKVSPRGEYEITDSLSLQIEDGKFVKGH-KTEKEWMDIGKPWELIEINESL 235

Query: 238 QTVEKRQGFKIACLEEIAWRNG--WLDDEGVKRAASSLAKTGYGQYLLELLRARPRQY 293
                 +G     +EE A  +G  +LD+  + R+   +       Y+ +     P  Y
Sbjct: 236 LN--NIKGEIKGTVEEGATLHGEVFLDEGSLIRSGVYIKGPV---YIGKDCDIGPNSY 288


>UniRef50_C7ICW0 Nucleotidyl transferase n=1 Tax=Clostridium papyrosolvens DSM 2782
           RepID=C7ICW0_9CLOT
          Length = 815

 Score =  295 bits (756), Expect = 1e-78,   Method: Composition-based stats.
 Identities = 59/278 (21%), Positives = 112/278 (40%), Gaps = 15/278 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +I+AGG G+RL P+T  + K ++P+ +KP++ + + +L   GI +I I         
Sbjct: 6   MKAVIMAGGEGSRLRPLTCDLPKPMVPVMNKPVLEHTIGLLKSYGITDIGITLLYHP-QI 64

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   G G   G+ + Y  + SP G A        FL  + + +V+  +          L
Sbjct: 65  IKDYFGSGHSHGVNIYYFLEESPLGTAGGIKNARDFL--DETFIVISGDSLTDLDIDKAL 122

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
           ++  ++   AT+   +V  P  +GVV  D+N       EKP   +  S+   TG+Y  + 
Sbjct: 123 KYHQSKKSIATLILAKVDVPLEYGVVLTDENGSVKGFVEKPSWGEIFSDMVNTGIYILEP 182

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +++ Y +  K  +        +    L +       +     W D G   S I +   + 
Sbjct: 183 EILSYIESGKKMD----FSKDVFPALLSSSKQIFGYVTNN-YWCDIGDTHSYINSHCDIL 237

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKT 276
             + +         E    N W+    +   ++ +   
Sbjct: 238 NGKLKINI-----GEQFNENVWVGPGTIIDKSARIIPP 270


>UniRef50_B8I5R7 Nucleotidyl transferase n=1 Tax=Clostridium cellulolyticum H10
           RepID=B8I5R7_CLOCE
          Length = 810

 Score =  295 bits (755), Expect = 2e-78,   Method: Composition-based stats.
 Identities = 64/278 (23%), Positives = 112/278 (40%), Gaps = 15/278 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK II+AGG G+RL P+T  + K ++PI +KP++ + + +L   GI +I I         
Sbjct: 1   MKAIIMAGGEGSRLRPLTCDLPKPMVPIMNKPVLEHTIGLLKSYGITDIGITLLYHP-QI 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   G G   G+ + Y  + SP G A        FL  + + +V+  +          L
Sbjct: 60  IKDYFGSGHSCGVNIYYFLEESPLGTAGGIKNAREFL--DETFIVISGDSLTDLNIENAL 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
            +  ++   AT+   +V  P  +GVV  D++       EKP   +  S+   TG+Y  + 
Sbjct: 118 EYHRSKKSIATLILTKVDVPLEYGVVLTDEDGSIKGFVEKPSWGEIFSDMVNTGIYILEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +++ Y +  K           +    L +       +     W D G   S I +   + 
Sbjct: 178 EILSYIEVGK----NTDFSRDVFPALLSSSKKIFGYVSND-YWCDIGDTRSYINSHYDIL 232

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKT 276
                +  KI   EE+   N W+    V    + +   
Sbjct: 233 ----NKNLKIDIGEELDE-NIWVGPGTVIDKNARIIPP 265


>UniRef50_A7NP37 Nucleotidyl transferase n=5 Tax=Chloroflexaceae RepID=A7NP37_ROSCS
          Length = 370

 Score =  293 bits (752), Expect = 4e-78,   Method: Composition-based stats.
 Identities = 71/291 (24%), Positives = 115/291 (39%), Gaps = 13/291 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +IL GG GTRL P+T    K ++P+ ++P I + L  L   GI E+++         
Sbjct: 1   MKAVILVGGLGTRLRPLTCNTPKPMIPLVNQPFIVHVLENLRNQGIDEVILCVQY-LADR 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F+  LGDGS  G+++   E+P P G A A    E  L+G     V   ++         L
Sbjct: 60  FREALGDGSVLGLKIHVIEEPEPLGTAGAVKNVEHMLDGSTF--VFNGDVLTDLDLRAML 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
                R    T+    V DP  +G+VE D+        EKP+  +  SN    G Y  + 
Sbjct: 118 AFHRERGSKLTIALTPVEDPTAYGLVEMDETGHIRRFMEKPRVDEITSNLINAGTYIIEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           ++  Y    +      +    +  + L+  +           W D GT  + +E    + 
Sbjct: 178 ELFRYVPPKQHY----MFERGLFPVVLQTRDPMYGYPSP-AYWTDIGTPSAYLEVHHDIL 232

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRAR 289
             + R  F     +EI  R   + D  +   A  +     G  +     A+
Sbjct: 233 VGKVRYRFHG---KEIGNRVWLVGDADIHPRAQVIGPVVIGPGVKIGAGAQ 280


>UniRef50_Q97EX5 Mannose-1-phosphate guanyltransferase (Pyrophosphorylase domain and
           phosphomannomutase domain) n=1 Tax=Clostridium
           acetobutylicum RepID=Q97EX5_CLOAB
          Length = 815

 Score =  293 bits (751), Expect = 4e-78,   Method: Composition-based stats.
 Identities = 66/280 (23%), Positives = 115/280 (41%), Gaps = 12/280 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK II+AGG G RL P+T  + K ++PI  KP++ Y + +L   GI EI I T       
Sbjct: 1   MKAIIMAGGQGKRLRPLTCNLPKPMMPIMQKPVLQYIIELLKKHGINEIGI-TLHYLPDE 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                GDG E G+ + Y  + SP G A +    E+FL  + + +V+  +       +  L
Sbjct: 60  VMDYFGDGKELGVNIHYFIEQSPLGTAGSVRNAESFL--DETFVVISGDALTDVNLTNIL 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDS 178
           ++   +    T+   +V  P  +GV   D   R  +  EKP   +  S+ A TG+Y  + 
Sbjct: 118 QYHKEKNAMVTIVLKKVTIPLEYGVAITDTEGRISNFIEKPGWGEIFSDKANTGIYVMEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
            + E+  + K  +  E     +    L++G      +     W D G  +  ++ +  + 
Sbjct: 178 GIFEFYNKDKKFDFSE----ELFPELLKSGKEIFGYVVND-YWRDIGNIEQFMKCNFDIL 232

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
                    I   +    +  W+    +      +    Y
Sbjct: 233 NGYVDVDVDIDASQH--QKGVWIGKNTIVSDNVKVIPPVY 270


>UniRef50_C7NU65 Glucose-1-phosphate thymidyltransferase n=5 Tax=Euryarchaeota
           RepID=C7NU65_HALUD
          Length = 357

 Score =  293 bits (751), Expect = 5e-78,   Method: Composition-based stats.
 Identities = 98/294 (33%), Positives = 146/294 (49%), Gaps = 7/294 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG++LAGG+G+RL PIT    KQLLP+ +KP++ Y +  L  AGI +I ++   + +  
Sbjct: 1   MKGVLLAGGTGSRLRPITHTGPKQLLPVANKPVLEYAVEDLKDAGITDIGVVLGHKGREA 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            Q LLGDGSE+G+ + Y  Q +P GLA A      F+  +   + LGDNI   QG    +
Sbjct: 61  IQELLGDGSEYGVDITYIVQGNPLGLAHAAGCARDFVGDDDFVMYLGDNIL-KQGIEDLV 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
               A   GA +   +V +P  FG+ E D +     L EKP  P SN A+ G+Y + + V
Sbjct: 120 ESFQAGEYGAGIALQEVQNPSEFGIAETDADGAVTRLVEKPADPPSNRALIGIYVFSNDV 179

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT- 239
            +  ++++PS RGELEIT   Q  LE GN     +     W DTG    +++A+  V   
Sbjct: 180 FDVIEELEPSWRGELEITDAIQDLLEEGNPIDSHVV-EGWWKDTGRPQDILDANRLVLED 238

Query: 240 VEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRARPRQY 293
           V   +  +I+   E+  R   L       A + +        +       P  Y
Sbjct: 239 VADDRAGEISTDAEVTGRVD-LAPSARVEAGAVIRGPVS---IEAGTTIGPGTY 288


>UniRef50_A7GSW4 Nucleotidyl transferase n=73 Tax=cellular organisms
           RepID=A7GSW4_BACCN
          Length = 785

 Score =  293 bits (750), Expect = 6e-78,   Method: Composition-based stats.
 Identities = 73/296 (24%), Positives = 117/296 (39%), Gaps = 16/296 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+ILAGG G RL P+T  V K +LP+ +KP++ Y + +L   GIREI I         
Sbjct: 3   MKGVILAGGKGRRLRPLTCNVPKPMLPLLEKPVLEYNIELLRRHGIREIAITVQY-LSNT 61

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDGS++G++L Y E   P G A +    E FL  +   +V+  +       +  +
Sbjct: 62  IREYFGDGSKWGVKLHYFEDSPPLGTAGSIKQAEAFL--DEPFVVISGDALTDFPLTEGI 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
                +    T+F  +V +P  FG+V  +     I   EKP   +  SN   TG+Y  D 
Sbjct: 120 VFHQQKKRMLTMFVKEVENPLSFGLVVMNKEQEIIRYMEKPSWNEVISNVVNTGIYIMDP 179

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
            +  Y      ++             LE  N           W+D GT +   +A   + 
Sbjct: 180 SIFSYIPPKTYADFSRHIFP-----LLENTNALFGYKA-EGYWMDIGTFEQYRQAQFDLL 233

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY-GQYLLELLRARPRQY 293
           T    +   +           W+ +       + +    + G  +     A    Y
Sbjct: 234 T----KKVNVTIPYTEVLPMVWMGEAVTIEKGTKIHGPSFIGDGVTIGAGAIVEPY 285


>UniRef50_C3LKU6 Nucleotidyl transferase family protein n=8 Tax=Bacillus
           RepID=C3LKU6_BACAC
          Length = 679

 Score =  293 bits (750), Expect = 7e-78,   Method: Composition-based stats.
 Identities = 71/296 (23%), Positives = 119/296 (40%), Gaps = 16/296 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+ILAGG G RL P+T    K +LP+ +KP++ Y + +L   GIREI I         
Sbjct: 1   MKGVILAGGKGRRLRPLTCNTPKPMLPLLEKPVLEYNIELLRQHGIREIAITVQYMSTA- 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            ++  GDGS++G+ L Y E   P G A +    E FL  + + +V+  +       S  +
Sbjct: 60  IKQYFGDGSKWGVNLYYFEDSPPLGTAGSIKQAEKFL--DETFVVISGDALTDFQLSKGI 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
                +    T+F  +V +P  FG+V  +         EKP   +  SN   TG+Y  + 
Sbjct: 118 TFHEQQKRMVTMFVKEVENPLSFGLVVMNKEQEVTRYIEKPSWNEVVSNIVNTGIYIMEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           ++  Y    +  +  +     +  +      L          WLD GT D   +A   + 
Sbjct: 178 EIFSYIPPREFFDFSQ----DVFPLLANKNALFAY--LSEGYWLDIGTFDQYRQAQFDLL 231

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY-GQYLLELLRARPRQY 293
           T    +  ++           W+ +       + +    + G+       A    Y
Sbjct: 232 T----KKLQVPIPYTEVLPMVWMGEGVTIGKGTKIHGPSFIGEGAKIGAGAVIEPY 283


>UniRef50_B5YF33 Mannose-1-phosphate guanyltransferase n=2 Tax=Dictyoglomus
           RepID=B5YF33_DICT6
          Length = 827

 Score =  291 bits (747), Expect = 1e-77,   Method: Composition-based stats.
 Identities = 60/290 (20%), Positives = 114/290 (39%), Gaps = 13/290 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +I+AGG GTRL P+T    K +  I  KP++ + +++L   G RE+   T       
Sbjct: 1   MRAVIMAGGEGTRLRPLTLTRPKPMTYIVGKPIMEHIINLLSEQGFRELT-ATLYYLPEI 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            Q    DGS + + L+Y+ + SP G A +          +   L++  +          +
Sbjct: 60  IQEYFDDGSNWNVNLDYSIEESPLGTAGSVKYALKN-KPKDRILIISGDALTDFNLREAI 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
           +         T+    V +P  +GVV   ++ + I   EKP   +  S+   TG+Y  + 
Sbjct: 119 KFHEENGALVTIVLTSVENPLEYGVVITKEDGKIIKFLEKPSWGEVFSDSVNTGIYILEP 178

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +V++Y    +P +        +  M LE        L +   W D G  +  ++A+    
Sbjct: 179 EVLDYIPDNQPFD----FSKDLFPMLLEKNAPLYGYLAQ-GYWCDIGNLEQFLQANFDAL 233

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRA 288
                +  KI           + ++E     ++ +    Y     ++   
Sbjct: 234 ----NKKVKIKIPGREILPGIYTNEEVEIATSAFIRPPVYIGQFTKISNN 279


>UniRef50_A0Q1V6 Mannose-1-phosphate guanyltransferase (Pyrophosphorylase domain and
           phosphomannomutase domain) n=4 Tax=Firmicutes
           RepID=A0Q1V6_CLONN
          Length = 817

 Score =  290 bits (743), Expect = 4e-77,   Method: Composition-based stats.
 Identities = 61/280 (21%), Positives = 111/280 (39%), Gaps = 14/280 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +I+AGG G RL P+T  + K ++PI +KP I Y + +L  +GI++I I         
Sbjct: 1   MKAVIMAGGLGNRLRPLTCNIPKPMMPIVNKPAIQYIIELLKNSGIKDIAITLQY-LADE 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                 DGS FG+ ++Y  +  P G   +    E FL  + + +V+  +          +
Sbjct: 60  IMSYFQDGSRFGVNIKYFIEDMPLGTGGSVKNAEEFL--DDTFIVISGDALINLDLRKVV 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDS 178
           ++  ++    T+   +V  P  +GVV  D+  R I   EKP   +  S+   TG+Y  + 
Sbjct: 118 KYHKSKNAQVTIVTKKVNTPLEYGVVITDNEGRIIKFLEKPGWSEVFSDKVNTGVYVLEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
            V++Y  + K           +  + L               W D G  +   + +  + 
Sbjct: 178 DVLKYYDKNK----QFDFSKDLFPLLLIKNKRIFSYTISE-YWCDIGDFNEYHKCNLDLL 232

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
               +        E    +N W+         + +    +
Sbjct: 233 NGIIKVKLDGKERE----QNIWIGRNCEISPKAKIIPPVF 268


>UniRef50_B9MMF1 Nucleotidyl transferase n=1 Tax=Anaerocellum thermophilum DSM 6725
           RepID=B9MMF1_ANATD
          Length = 712

 Score =  289 bits (741), Expect = 8e-77,   Method: Composition-based stats.
 Identities = 61/280 (21%), Positives = 120/280 (42%), Gaps = 18/280 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+I+AGGSGTRL P+T  + K ++P + KP++ Y + +L   GI EI           
Sbjct: 1   MKGVIMAGGSGTRLRPLTVSLPKPMIPFFGKPVMEYAVKLLKAHGIFEIATTLQYHPDKI 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                 DG ++G+ +++  +  P G A +    + FL  + + +VL  +       +  +
Sbjct: 61  I-NYFEDGQKWGVNIQHFVEDRPLGTAGSVKNAKVFL--DDTFVVLSGDGITNADLTRAI 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDS 178
                +    T+   +V  P  +G+V  D+  +     EKP   +  SN A TG+Y  + 
Sbjct: 118 EFHKQKGSKVTIVLKEVEIPIEYGIVLTDEEGKIQRFFEKPSWSEVFSNLANTGIYIIEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           ++++Y +  KP +        +    L+              W D G   S I+A   + 
Sbjct: 178 EILDYIEDGKPFD----FSKDLFPKLLKEKVPMFGF-KMDGYWCDIGDVGSYIKAHRDI- 231

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
                  FK+  + ++  ++  +         + ++++ +
Sbjct: 232 -------FKLGGILDLDLKSSQISKNSNISLNAKISRSVF 264


>UniRef50_B7GHA3 Nucleoside-diphosphate-sugar pyrophosphorylase fused to
           phosphomannomutase n=1 Tax=Anoxybacillus flavithermus
           WK1 RepID=B7GHA3_ANOFW
          Length = 815

 Score =  288 bits (739), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 65/280 (23%), Positives = 113/280 (40%), Gaps = 15/280 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +K +I+AGG GTRL P+T  V K ++PI +KP++ Y +  L   GI +I +         
Sbjct: 23  VKAVIMAGGRGTRLRPLTCHVPKPIVPIMNKPVMAYSIEWLKHHGITDIAVTVQYLSDEI 82

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDG  FG++L Y E+ +P G A +    ++FL  + + +V+  +I         +
Sbjct: 83  IE-YFGDGRRFGVRLHYFEETTPLGTAGSVKHAQSFL--DDTFVVISADILTTMHLQQAI 139

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
               ++    TV  +    P  +G +  D N + I   EKPK  +  S+   TG+Y  D 
Sbjct: 140 HFHFSKQALVTVLMHHEATPLSYGGIVTDRNGKVIHFVEKPKWNEVCSDLVNTGIYICDP 199

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
            +  Y  +  P +  +     I    ++              W D G  +   +    + 
Sbjct: 200 AIFNYMPEHPPYDFSQH----IFPHLIQQKYPIYGY-EADGYWSDIGVIEQYHQTHVDLL 254

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
                Q    +  +EIA    W+ +         L     
Sbjct: 255 ----NQRLIPSHYKEIAPD-VWIGERVNIAQGVKLEGPIL 289


>UniRef50_C1DV53 Mannose-1-phosphate guanyltransferase n=4 Tax=cellular organisms
           RepID=C1DV53_SULAA
          Length = 830

 Score =  288 bits (738), Expect = 2e-76,   Method: Composition-based stats.
 Identities = 64/263 (24%), Positives = 111/263 (42%), Gaps = 13/263 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +I+AGG GTR+ P+T  + K +LP+ +KPM+ + +  +   GI EI+I+        
Sbjct: 1   MKAVIMAGGFGTRIQPLTNSIPKPMLPVLNKPMMEHIIKKVKAVGITEIVILL-YFKPEV 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            Q    DGS+FGI++ Y       G A A      +L  +   +V+  ++         +
Sbjct: 60  IQNYFKDGSDFGIKINYVLPDDDYGTAGAVKKAAKYL--DERFIVISGDLVTDFDLKEII 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDS 178
               A     T+    V DP +FGVV  D + + +   EKP   +  S+   TG+Y  + 
Sbjct: 118 GFHQAVGSKLTITLTSVEDPLQFGVVITDKDGKILRFLEKPGWGEVFSDTINTGIYVIEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +++ Y     P +        +    ++ G        +   W D G  +S  E +  + 
Sbjct: 178 EILNYIPDNLPFD----FSKDLFPKLMKEGITLYGYNAK-GYWRDVGNPESYREVNKDIL 232

Query: 239 TVEKRQGFKIACLEEIAWRNGWL 261
             + +   +    E I    G L
Sbjct: 233 LDKVKLDVEG---ERIKVNGGVL 252


>UniRef50_A3DL04 Nucleotidyl transferase n=1 Tax=Staphylothermus marinus F1
           RepID=A3DL04_STAMF
          Length = 837

 Score =  288 bits (737), Expect = 2e-76,   Method: Composition-based stats.
 Identities = 58/290 (20%), Positives = 115/290 (39%), Gaps = 9/290 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +K II+AGG GTRL P+T    K L+P+ +KP++ + + +L   G ++I  +T       
Sbjct: 2   VKAIIMAGGEGTRLRPLTVNRPKPLVPLVNKPLMEHVVHLLKSKGFKDIG-VTLHYLPNT 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
             R  GDGSEFG+++ Y+ +  P G A          + + + +V+  ++F        L
Sbjct: 61  IMRYFGDGSEFGVRIYYSIEEKPLGTAGGVRFLADKYDWDETIIVISGDVFTNIDLEKML 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDS 178
            +   +    T+   +  DP ++G+   D+  R     EKP   +  S+    G+Y  + 
Sbjct: 121 EYHRRKGSIFTMAVRKTDDPTKYGIALLDEEGRVRRFLEKPSWSEVFSDLINMGIYILEP 180

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           + +E      PS        ++    L             + W D G+ +   E    + 
Sbjct: 181 EALEMI----PSNEEYDFAKNLIPKLLRFDKPVYGWRADNYYWSDIGSINQYKETHNDIL 236

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRA 288
           +   + G   + L     +  ++ +        ++           + + 
Sbjct: 237 SG--KVGIDTSMLGLEVAKGVYVGENTSIDDIDNIIPPVVIGKDTRIKKN 284


>UniRef50_Q1AW30 Nucleotidyl transferase n=1 Tax=Rubrobacter xylanophilus DSM 9941
           RepID=Q1AW30_RUBXD
          Length = 833

 Score =  287 bits (736), Expect = 3e-76,   Method: Composition-based stats.
 Identities = 65/292 (22%), Positives = 113/292 (38%), Gaps = 21/292 (7%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +I+AGG GTRL P+T    K ++ I + P + + +++L   G  +I +         
Sbjct: 1   MKAVIMAGGQGTRLRPLTSEQPKPMIRIANVPCMEHIVNLLKRHGFTDIAVTLQFMPDE- 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGE-PSCLVLGDNIFFGQGFSPK 119
            +   GDGS++G+ + Y+ + SP G A +  + E  L  E    L++  +          
Sbjct: 60  IRDYFGDGSDWGVNIRYSVEDSPAGTAGSVKMAERQLGLEGERLLIISGDALTDVDLGEL 119

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYD 177
           L +   +   AT+    V +P  FG+V   ++ R     EKP   Q  S+   TG+Y  +
Sbjct: 120 LAYHEQKGGEATMVLKSVENPLDFGIVITGEDGRISRFLEKPAWGQVFSDTVNTGIYLLE 179

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
             V+       P E        +    LE G     ++     W D GT +    A+  V
Sbjct: 180 PSVLREIPD--PEEGEYDFSKDLFPRLLEQGRPLYGMV-TDAYWEDIGTLEQYASANRDV 236

Query: 238 QTVEKR--------------QGFKIACLEEIAWRNGWLDDEGVKRAASSLAK 275
                R               G ++   +E       + D       + ++ 
Sbjct: 237 LEGRVRGVRPPGTRLRENIYVGRRVQVDDEELEGPVVIGDNVRIDEGARISP 288


>UniRef50_C0LTM3 Glucose-1-phosphate thymidylyltransferase n=6 Tax=Actinomycetales
           RepID=C0LTM3_9ACTO
          Length = 331

 Score =  287 bits (735), Expect = 3e-76,   Method: Composition-based stats.
 Identities = 157/293 (53%), Positives = 204/293 (69%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKGII+AGGSG+RL P+T  +SKQLLP+Y+KPMIYYPLSVLMLAG+ E+LII++P+    
Sbjct: 1   MKGIIMAGGSGSRLKPLTGVLSKQLLPVYNKPMIYYPLSVLMLAGVTEVLIISSPQHLPL 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F+ +LGDG   G++L YAEQ  P G+A+AF+IG   +  +   LVLGDNIF G GFS  L
Sbjct: 61  FRAMLGDGDRLGMRLTYAEQHRPAGIAEAFLIGAGHIGDDSVSLVLGDNIFHGPGFSALL 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           R  A R +G T+FGY V DP R+GV   D       +EEKP +P+S  AVTGLY YD+ V
Sbjct: 121 REQARRVDGCTLFGYPVRDPHRYGVAVVDSGGHLTDIEEKPDRPRSELAVTGLYMYDNDV 180

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           V  A+ ++PS RGELE+T IN+ YLE G   +  LGRGF WLDTGTH++L+EA  +V  +
Sbjct: 181 VGIARGLRPSARGELEVTDINRAYLERGKARLVQLGRGFVWLDTGTHEALLEAGQYVHIL 240

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRARPRQY 293
           E+RQ  +IACLEEIA+R G++D   ++R     A T YG YL E+    P  +
Sbjct: 241 EQRQSVRIACLEEIAFRMGFIDRAALQRLGREHADTDYGAYLTEIADKPPATW 293


>UniRef50_A6TTZ6 Nucleotidyl transferase n=1 Tax=Alkaliphilus metalliredigens QYMF
           RepID=A6TTZ6_ALKMQ
          Length = 825

 Score =  287 bits (735), Expect = 4e-76,   Method: Composition-based stats.
 Identities = 61/279 (21%), Positives = 109/279 (39%), Gaps = 14/279 (5%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K II+AGG GTRL P+T  + K ++PI +KP + Y + +L    I++I +          
Sbjct: 5   KAIIMAGGKGTRLKPLTCNIPKPMVPILNKPTMEYTVELLRKHNIKDIAVTIAH-LPTVI 63

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLR 121
                DG ++ + L Y  + +P G   +    E F+  + + +VL  +          + 
Sbjct: 64  TDYFHDGGKWDVNLSYYTEETPLGTGGSVKNAEEFI--DDTFIVLSGDSLTDINIKKAIE 121

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDSK 179
               +   AT+       P  +GVV  +DN R     EKP   +  SN   TG+Y  + +
Sbjct: 122 FHKNKGSKATLILKNEQMPIEYGVVITNDNGRITRFLEKPSWGEVFSNTINTGMYILEPE 181

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           V++Y +              +    LE        +     W D G  +S  E    + +
Sbjct: 182 VLDYFQPG----ENFDFSKDLFPKLLEDDIPMYGYVTED-YWCDVGALNSYTETHFDILS 236

Query: 240 VEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
            +   G +   +E+      W+ +     +   +    Y
Sbjct: 237 GKVNIGLEGHQIED----GIWVGEGTQIGSGVKITPPVY 271


>UniRef50_C9RWA3 Nucleotidyl transferase n=7 Tax=Geobacillus RepID=C9RWA3_GEOSY
          Length = 347

 Score =  286 bits (734), Expect = 4e-76,   Method: Composition-based stats.
 Identities = 70/297 (23%), Positives = 114/297 (38%), Gaps = 17/297 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++LAGG GTRL P+T  + K + PI ++P + + +  L   G+ E +I         
Sbjct: 1   MKALLLAGGLGTRLRPLTENIPKPMAPIANRPWLEHLIVHLRDQGVNEFVIA-AHHCSEV 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +R   DG  + +++ YA +P P G A A    E +L      LV   +I       P L
Sbjct: 60  IRRYFEDGKRWNVKITYALEPFPLGTAGAIKNAERWLK--ERFLVFNADIVHLPQLIPLL 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDS 178
                    AT+   +V DP  +GVVE DD  + +   EKP  ++  SN    G+Y ++ 
Sbjct: 118 DFHRQHGGLATIVLTEVDDPSSYGVVEQDDRGQILRFVEKPRREEAPSNRINAGMYIFEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
            V+ Y     P+ER          + +E       ++     W D GT     +      
Sbjct: 178 DVMRYI----PAEREVSIERETFPLLIEKNVGVYGIV-SNGYWRDMGTPARYRQVHWDAL 232

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY-GQYLLEL--LRARPRQ 292
               R+ F I           ++ +     +          G ++         P  
Sbjct: 233 ----RREFPIPLKGREIQPGVFVGENVEIGSGVLFVPPVLIGDHVKIGPQAVIGPNA 285


>UniRef50_C0GGS0 Nucleotidyl transferase n=1 Tax=Dethiobacter alkaliphilus AHT 1
           RepID=C0GGS0_9FIRM
          Length = 385

 Score =  286 bits (733), Expect = 5e-76,   Method: Composition-based stats.
 Identities = 67/279 (24%), Positives = 115/279 (41%), Gaps = 14/279 (5%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K +ILA G GTRL P+T  VSK ++ + ++P + + + +L   G+++I++      +   
Sbjct: 32  KAMILAAGLGTRLRPLTNSVSKPMVEMANRPCMEHAVRLLAKYGVKDIVVNLHYMPE-II 90

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLR 121
           Q   GDGS FG+ + Y+ +    G A  F   + F   EP  L++  +           +
Sbjct: 91  QEHFGDGSAFGVNITYSYEKELMGTAGGFKRVQKFFGDEP-ALIISGDALTDVNLEQLYK 149

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDSK 179
                   AT+   QV DP ++GVV  + N + +  +EKP  ++  SN A TG+Y +D +
Sbjct: 150 FHKENEAIATLALKQVADPTQYGVVVREGN-KIVQFQEKPKLEEAISNLANTGIYLFDPR 208

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           + ++       + G      +    LE G      + +   W D G      EA   + T
Sbjct: 209 IFDHIPADTFYDFG----KQVFPELLEKGEKMCGYVMKE-YWCDVGDLTMYREAHYDMLT 263

Query: 240 VEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
              R         +    N W  D         +     
Sbjct: 264 GVVRVEL----PGKELPGNIWFGDRVSVHPDVKIVGPVL 298


>UniRef50_Q3A0B4 Mannose-1-phosphate guanyltransferase n=10 Tax=Desulfuromonadales
           RepID=Q3A0B4_PELCD
          Length = 842

 Score =  285 bits (731), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 65/272 (23%), Positives = 116/272 (42%), Gaps = 11/272 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +I+AGG GTR+ P+T  + K ++P+ ++P++ + + +L   GI +++++   + +  
Sbjct: 1   MKAVIMAGGFGTRMQPLTINLPKPMVPLVNQPIMSHIIDLLKAHGISDVIMLLFHQPE-I 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDGSE G+++ Y       G A A      +L  +   LV+  ++         L
Sbjct: 60  IKNYFGDGSELGVRITYVTPLEDFGTAGAVKAAAPYL--DERFLVISGDLLTDFDLGAVL 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDS 178
                +   AT+    V DP +FGVV  D         EKP   +  S+   TG+Y  + 
Sbjct: 118 SFHEEKQALATITLTSVEDPLQFGVVITDQQGAITKFLEKPGWGEVFSDTINTGIYVLEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +V+E   +    E        I    LE G      L +   W D G  D+ +E    + 
Sbjct: 178 EVLEMIPE----ETNRDWSKDIFPRMLEEGRPLYGCLQQ-GYWADIGNTDAYLETCRDLW 232

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAA 270
             +         L + + R  +L  + +   A
Sbjct: 233 HGKVAASLPEPTLSDGS-RQIYLGTDTLVAEA 263


>UniRef50_B0BZX4 Phosphoglucomutase/phosphomannomutase family Nucleotidyl
           transferase n=23 Tax=Bacteria RepID=B0BZX4_ACAM1
          Length = 844

 Score =  285 bits (730), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 67/281 (23%), Positives = 115/281 (40%), Gaps = 15/281 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +++AGG GTRL P+T  + K ++PI ++P+  + +++L    I EI I T       
Sbjct: 1   MRAVLMAGGEGTRLRPLTCDLPKPMVPILNRPIAEHIVNLLKHHQIYEI-IATLYYLPDV 59

Query: 61  FQRLLGDGSEFGIQLEY-AEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK 119
            +    DGS+FG+Q+ Y  E+    G A         L    + LV+  +       +  
Sbjct: 60  MRDYFRDGSDFGVQMTYGIEEEQALGTAGCVKNISALLTD--TFLVISGDCITDFDLTAA 117

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYD 177
           ++    +   AT+   +V DP  FGVV  D + +     EKP   +  S+   TG+Y  +
Sbjct: 118 IKFHRQKGSKATLVLARVPDPMEFGVVITDQSHQICRFLEKPSTSEVFSDTVNTGIYILE 177

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
            +V++Y     PS++       +  + LE G      +     W D G+ DS  EA    
Sbjct: 178 PEVLDYL----PSDQQTDFSKDLFPLLLEKGEPMFGYVA-EGYWCDVGSLDSYREAQYDA 232

Query: 238 QTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
                    +I    +      W+         + L     
Sbjct: 233 LQG----NVRIEFAYQEMNPGLWMGQNVHVDPEAKLHPPIL 269


>UniRef50_Q7NNE0 Mannose-1-phosphate guanyltransferase n=5 Tax=Gloeobacter violaceus
           RepID=Q7NNE0_GLOVI
          Length = 327

 Score =  283 bits (726), Expect = 4e-75,   Method: Composition-based stats.
 Identities = 67/279 (24%), Positives = 119/279 (42%), Gaps = 11/279 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK  +LA G GTRL P T  + K L+P+ +KP++ + L++    G  +I+       +  
Sbjct: 1   MKAFVLAAGKGTRLRPFTDALPKPLMPVVNKPVMTHILALCRKHGFDQIVANLHYRGEKI 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +R   DG   G++L Y+ +    G A        FL G+ + LV+  ++         +
Sbjct: 61  AER-FADGHRHGVELRYSWEEQLLGTAGGVRRQADFLAGD-AFLVISGDVMTDLDLGALV 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQP--KSNWAVTGLYFYDS 178
           R        AT+   +V DP RFGVV  D + R  S +EKP +   +S  A TG+Y  + 
Sbjct: 119 RFHKQSGAVATMAVKEVGDPSRFGVVLTDPDGRVESFQEKPAKGSERSRLANTGIYVLEP 178

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +V E+  +    + G      +  + +  G   V  +  G  W D GT    +     + 
Sbjct: 179 EVFEHIPEAAFFDFG----NDLFPLLVSKGAP-VYAMRTGAYWSDVGTLSQYLYTHWELL 233

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTG 277
           T  + +    A    +      + ++ +  +  ++ K  
Sbjct: 234 THPELKQRVGAN--TVVESGAVVSEQALIGSGCTIEKGA 270


>UniRef50_C1SHR4 Nucleotidyltransferase n=1 Tax=Denitrovibrio acetiphilus DSM 12809
           RepID=C1SHR4_9BACT
          Length = 830

 Score =  283 bits (724), Expect = 6e-75,   Method: Composition-based stats.
 Identities = 64/277 (23%), Positives = 117/277 (42%), Gaps = 11/277 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +++AGG GTR+ P+T  + K ++P+ +KPM+ Y +  L  AGI EI+I+        
Sbjct: 1   MKAVVMAGGFGTRIQPLTSSMPKPMIPVMNKPMMEYIIDALKEAGIVEIVILL-YFKPEV 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDGS  GI++ Y       G A A    + +L  +   +++  ++     F   L
Sbjct: 60  IKNYFGDGSSKGIKIHYVLPDDDYGTAGAVKKAQKYL--DERFIIVSGDLISDFSFQEIL 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDS 178
                +   AT+    V DP +FGVV  D   + I   EKP   +  S+   TG+Y ++ 
Sbjct: 118 GFHDVKNSKATITLTSVPDPLQFGVVITDKESKIIRFLEKPGWGEVFSDTINTGIYVFEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +++EY  +    +        +    + +G        +   W D G  DS   A   + 
Sbjct: 178 EILEYIPE----DSNFDFSKDLFPKLMASGIDLFGYNAK-GYWRDVGNPDSYRAALLDIL 232

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAK 275
             +     +    E+++    +   +      + +  
Sbjct: 233 NEDVTLPLEG-IQEKLSEGTVYKGKDVKIHKTAKIEG 268


>UniRef50_C7LZ98 Nucleotidyl transferase n=1 Tax=Acidimicrobium ferrooxidans DSM
           10331 RepID=C7LZ98_ACIFD
          Length = 854

 Score =  282 bits (723), Expect = 1e-74,   Method: Composition-based stats.
 Identities = 72/296 (24%), Positives = 121/296 (40%), Gaps = 15/296 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +I+AGG GTRL P+T    K LLP+ ++PMI   + +L+  GI +I++         
Sbjct: 1   MQAVIIAGGEGTRLRPLTSTTPKPLLPVANRPMIARVVDLLVANGIDDIIVTVAY-LGSA 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  LGDG+++G ++ Y ++ SP G A A       L  E + +VL  ++          
Sbjct: 60  IRTYLGDGTDWGARIRYLQEESPLGTAGAVRNARHLL--EDTFIVLSGDVVTTVDLEAAR 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
           R    R   AT+    V DP  FGVV  +D+     L EKP   +  ++   TG+Y  + 
Sbjct: 118 RFHHERGASATMVLTTVPDPTEFGVVATEDSGAVTRLIEKPSWGEVFTDTVNTGVYILEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
            V++     +  +  E     +    L+        +     W D GT     +    V 
Sbjct: 178 SVLDRIPANRAVDFSE----EVFPQILDDRGALFGYVA-DGYWADVGTFSGFHQTHHDVL 232

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLA-KTGYGQYLLELLRARPRQY 293
             + R G   +  E       ++ D      ++ L      G  +     +R   Y
Sbjct: 233 --DGRAGIAPSGFELAP--GVYVGDRSTIDPSALLEAPCIVGNDVRIGPGSRLGPY 284


>UniRef50_Q55689 Glucose-1-phosphate thymidylyltransferase n=52 Tax=cellular
           organisms RepID=Q55689_SYNY3
          Length = 393

 Score =  280 bits (718), Expect = 4e-74,   Method: Composition-based stats.
 Identities = 91/279 (32%), Positives = 143/279 (51%), Gaps = 6/279 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +IL+GG GTRL P+T   +KQL+P+ +KP+++Y +  +  AGI +I II +PE    
Sbjct: 29  MKALILSGGKGTRLRPLTYTGAKQLVPVANKPILWYGIEAIAKAGITDIGIIISPETGEE 88

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            + + G+G +FGIQ+ Y  Q  P GLA A      FL   P  + LGDN+         L
Sbjct: 89  IKTITGNGEKFGIQITYILQSEPLGLAHAVKTAADFLQDSPFVMYLGDNLIQDH-LEQFL 147

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
            H  A++  + +   +V +P  FGV   +D  + ++L EKP+ P SN A+ GLYF+   +
Sbjct: 148 AHFQAKSLDSLILLRRVSNPSAFGVATVNDQGKVLALVEKPEHPPSNLALVGLYFFAPTI 207

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            +    ++PS RGELEIT   Q  + + +  VE L     WLDTG  D L+ A+  +   
Sbjct: 208 HQAIANIEPSARGELEITDAIQYLI-SHDYRVESLQLKGWWLDTGKKDDLLAANQIILDT 266

Query: 241 EKRQGFKIACLEE--IAWRNGWLDDEGVKRAASSLAKTG 277
              +  +    ++  I+ R        +  +   +    
Sbjct: 267 LVEKNIQGTVDDQSKISGRVTIGPHSQIINS--VIRGPV 303


>UniRef50_Q0AV26 Mannose-1-phosphate guanyltransferase n=1 Tax=Syntrophomonas wolfei
           subsp. wolfei str. Goettingen RepID=Q0AV26_SYNWW
          Length = 343

 Score =  279 bits (715), Expect = 7e-74,   Method: Composition-based stats.
 Identities = 59/267 (22%), Positives = 117/267 (43%), Gaps = 10/267 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +I+A G G+RL P+T+   K ++P+ ++P++   + +L     +E++     + +  
Sbjct: 1   MKAMIMAAGVGSRLMPLTKDTPKPMVPMTNRPLMENIVELLGRHHFKEVIANLHHQGES- 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                 DG +FG++L Y+ +    G A      E FL  + + +V+  +       S  L
Sbjct: 60  ISGYFDDGHDFGLKLLYSPEEVLLGTAGGVKKCEWFL--DETFVVISGDALTDMDLSELL 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDS 178
                R   AT+   +V + E+FGVV   ++ R    +EKP  ++  S+ A TG+Y ++ 
Sbjct: 118 AQHRKRGALATIALKEVENVEQFGVVLTAEDGRISRFQEKPGREEALSHQANTGIYVFEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           ++ +Y    +  + G      +    +E G     +  +   W D G  ++  +A+  V 
Sbjct: 178 EIFKYIPAAQFYDFGC----QLFPQLVEMGAPFYAVSTQD-YWCDVGNIETYRQANVDVL 232

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEG 265
                       LE+       L ++ 
Sbjct: 233 QGRVAMKPGGIVLEDKGKSRVLLGEDV 259


>UniRef50_B0K747 Nucleotidyl transferase n=10 Tax=Thermoanaerobacteraceae
           RepID=B0K747_THEP3
          Length = 776

 Score =  278 bits (712), Expect = 1e-73,   Method: Composition-based stats.
 Identities = 59/279 (21%), Positives = 116/279 (41%), Gaps = 16/279 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKGII+AGG G+RL P+T  + K ++P+ +KP I + +  L   GI+++  +T       
Sbjct: 1   MKGIIMAGGEGSRLRPLTADIPKPMVPVANKPAIKHIVEHLHKYGIKDLA-VTLFYLPQK 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            ++ L    E+G ++++  +  P G A +      FLN   + +V+  ++          
Sbjct: 60  IKKYLE--EEYGDEIKFYIEDKPLGTAGSVKNARDFLND--TFIVMSGDVITDVNIKEAY 115

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
                +    T+   +V  P  +GVV  D+  +     EKP   +  S+   TG+Y  + 
Sbjct: 116 EFHRKKGAKVTLILTRVDVPLEYGVVIVDEEGKIKKFLEKPSWGEVFSDTVNTGIYIIEP 175

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +++E+  Q KP +        +  M L+        +  G  W D G  +  I +   + 
Sbjct: 176 EILEFIPQDKPFD----FSKDLFPMLLKNDIPMYGYI-TGGYWCDIGNTNQYITSHFDIL 230

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTG 277
                 G+K    +++  +   +         + +    
Sbjct: 231 EGRVDLGYK----DKLLKKGKVIGKNVTISPEAKIIPPV 265


>UniRef50_A7HN10 Glucose-1-phosphate thymidyltransferase n=9 Tax=cellular organisms
           RepID=A7HN10_FERNB
          Length = 376

 Score =  278 bits (712), Expect = 2e-73,   Method: Composition-based stats.
 Identities = 93/279 (33%), Positives = 138/279 (49%), Gaps = 5/279 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK IIL  G GTRL P+T   +K L+P+ +KP+I Y +  +   GI++I II +PE+K  
Sbjct: 18  MKAIILCAGKGTRLRPLTYTTAKHLIPVANKPVILYTIEKIKSVGIKQIGIIVSPENKAD 77

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F+  LGDGS++G+++ Y  QP P GLA A ++ + FL  E   + LGDN+       P +
Sbjct: 78  FEENLGDGSKYGVEITYILQPEPKGLAHAVLMAKDFLGDEDFMMYLGDNLIMD-DIRPFV 136

Query: 121 RHVAARTE-GATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSK 179
                R    A +    V DP RFG+   + N R +   EKPK+P SN A+ GLY +   
Sbjct: 137 DEFEQRKNISALIMLSPVNDPTRFGIAVMEGN-RIVKTVEKPKEPPSNLAIIGLYLFRKD 195

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ- 238
           + E    +KPS RGELEIT      ++        +     W DTG  + L+EA+  +  
Sbjct: 196 IFEGIANIKPSWRGELEITDAIDWLIQNKGNVEGHIIY-GWWKDTGKPEDLLEANHKILD 254

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTG 277
            + +    K         +      EG +   S +    
Sbjct: 255 DIIEEFKIKGTVEASSVIQGRVSIGEGTEVVNSVIRGPV 293


>UniRef50_Q3Z778 Nucleotidyltransferase family protein n=5 Tax=Dehalococcoides
           RepID=Q3Z778_DEHE1
          Length = 361

 Score =  277 bits (710), Expect = 3e-73,   Method: Composition-based stats.
 Identities = 63/292 (21%), Positives = 111/292 (38%), Gaps = 22/292 (7%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK IIL GG GTRL P++    K ++P+ + P + + L  L   GI++I++ T       
Sbjct: 1   MKAIILVGGQGTRLRPLSINTPKSMVPVLNVPFLSHVLRYLSSCGIKDIIL-TQGHLAAP 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            ++  G+G   G+ L Y+ +    G A A    E +L  + + + L  +IF     S  L
Sbjct: 60  IEQYFGNGQSLGVNLVYSVEHEALGTAGAIKNAERYL--DDTFITLNGDIFTHLDLSAML 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQP--KSNWAVTGLYFYDS 178
           R    +    ++    V DP ++G+VE  D  R     EKP      +N    G Y  + 
Sbjct: 118 RAHRDKKALVSIALTPVDDPTKYGLVETADGGRVSRFLEKPSPAQITTNMINAGTYIIEP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +V++Y     P+         +    L               W+D G+ +   + +  + 
Sbjct: 178 EVLKYI----PAGENHSFERQLFPRLLNECQAVYAYP-SSAYWIDIGSPEKYSQLNRDLL 232

Query: 239 TVEKRQGFKIACLEEIAWRN------------GWLDDEGVKRAASSLAKTGY 278
             E          E +  R               + +  +  A + +A    
Sbjct: 233 CGEGGDFGFSRGNEIVIGRGCQLHPTARISGPVLVGENCIIGANACIAGPVV 284


>UniRef50_UPI0001C315BB Nucleotidyl transferase n=1 Tax=Conexibacter woesei DSM 14684
           RepID=UPI0001C315BB
          Length = 366

 Score =  277 bits (710), Expect = 3e-73,   Method: Composition-based stats.
 Identities = 76/290 (26%), Positives = 120/290 (41%), Gaps = 17/290 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +ILAGG GTRL P+T  V K ++P+ D+P I + L  L   G+ +++I       G 
Sbjct: 1   MQALILAGGEGTRLRPLTSTVPKPVVPLVDRPFIAFMLDWLRRHGVDDVVISCGFMASG- 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            + +LGDGS FGI+L Y E+P P G   A    E  L  +   LVL  ++      + +L
Sbjct: 60  VRNVLGDGSAFGIRLRYVEEPRPLGTGGAIKFAEPLL--DERVLVLNGDVLTDIDLTAQL 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
                     T+    V DP  +G+V  D++       EKP   Q  +N    G Y  + 
Sbjct: 118 AQHERTGARVTLALIAVDDPSAYGLVRRDEDGGVREFLEKPSPDQIDTNLVNAGAYVLER 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +V++      P+ER       +    +  G            WLD GT +  ++AS  + 
Sbjct: 178 EVLDAI----PTERAVSVEREVFPTLVRNGL---YGYEASGYWLDIGTPERYLQASHDIL 230

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRA 288
                   + +  E    RN  + D   +     +     G  +     A
Sbjct: 231 DG----AVETSVPEAFDSRNVAIADSA-EVQGRVVGPALVGPGVRIAAGA 275


>UniRef50_Q8SQX7 MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE n=3 Tax=Microsporidia
           RepID=Q8SQX7_ENCCU
          Length = 345

 Score =  277 bits (709), Expect = 3e-73,   Method: Composition-based stats.
 Identities = 64/289 (22%), Positives = 116/289 (40%), Gaps = 17/289 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +K +IL GG GTRL P+T  V K L+P  +KP++ + +  L+  GI+EI++      +  
Sbjct: 8   VKAVILVGGYGTRLRPLTYTVPKPLVPFANKPILRHQIEALVKVGIKEIILALNYYSEFI 67

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            + +    +E GI + Y+++  P G A    + + +L G  +  VL  +I      +  L
Sbjct: 68  IREVRDYSNELGISIVYSKEQEPLGTAGPLALAKKYLEGH-TFFVLNSDITCRFPLAEML 126

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDN-FRAISLEEKPKQPKSNWAVTGLYFYDSK 179
               +     T+    V DP R+G++  +++     S  EKPK   SN    G+Y  +  
Sbjct: 127 SFHYSHGREGTILSTNVDDPSRYGIIITEESTSLVRSFLEKPKDAVSNRVNAGIYILNPS 186

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           V++  +  + S   E     I     E   L  ++      W+D G     I+       
Sbjct: 187 VLDRIELRECSIERE-----IFPRMAEEHQL--QVFDLKGFWMDIGQPADYIKGQGMYLR 239

Query: 240 VEKRQGFK-------IACLEEIA-WRNGWLDDEGVKRAASSLAKTGYGQ 280
             +  G          +  + +   RN  +        ++       G 
Sbjct: 240 HCQEAGIDNQLDAKMFSIEDNVVIGRNVRIGRNVTISNSAIFDNVEIGD 288


>UniRef50_B3QV42 Nucleotidyl transferase n=1 Tax=Chloroherpeton thalassium ATCC
           35110 RepID=B3QV42_CHLT3
          Length = 847

 Score =  276 bits (707), Expect = 6e-73,   Method: Composition-based stats.
 Identities = 65/280 (23%), Positives = 114/280 (40%), Gaps = 14/280 (5%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K II+AGG GTRL P+T  + K L+P+  +PM+++   +L   G++EI  +   + +   
Sbjct: 12  KAIIMAGGFGTRLRPLTMNIPKPLVPMMQRPMMHHIAELLKKYGVKEITSMLYYQPES-I 70

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLR 121
           +   GDG +FG ++ Y    +  G A +      F++G    +V+  ++      S  + 
Sbjct: 71  REYFGDGKKFGYKMHYILSDADYGTAGSVRNAYDFVDGR--FVVISGDVLTDFDLSKAIE 128

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDSK 179
               R   AT+    V +P +FGVV  D + R     EKP   +  S+   TG+Y  + +
Sbjct: 129 FHVKRGALATMVLTHVKNPLQFGVVITDKDGRITRFLEKPTWGEVFSDTINTGIYILEKE 188

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           V++      P +        +    L+        +     W D GT     EA      
Sbjct: 189 VMDLI----PYKEDYDFSKDLFPKMLKENMPLYGYI-SNGYWRDVGTLTEYQEAHIDCLN 243

Query: 240 VEKRQGFKIA----CLEEIAWRNGWLDDEGVKRAASSLAK 275
            +    F         +  A ++  +D   VK +      
Sbjct: 244 GKVNLDFTYDYEKIADDVYAHKSAKVDLNSVKFSGKVYIG 283


>UniRef50_C6PCK2 Nucleotidyl transferase n=1 Tax=Thermoanaerobacterium
           thermosaccharolyticum DSM 571 RepID=C6PCK2_CLOTS
          Length = 781

 Score =  276 bits (706), Expect = 9e-73,   Method: Composition-based stats.
 Identities = 58/278 (20%), Positives = 112/278 (40%), Gaps = 16/278 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK II+AGG G+RL P+T G+ K ++PI  KP I++ ++ +   GI ++  +T       
Sbjct: 1   MKAIIMAGGEGSRLRPLTCGIPKPMVPIAGKPAIWHIINHIGRYGINDLG-VTLFYLPDK 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  L    ++G +++Y  +  P G A +      FL  + + +V+  ++          
Sbjct: 60  IKNYL--YEQYGDKIKYYVEDKPLGTAGSVKNAVDFL--DETFVVMSGDVITDIDLRKAH 115

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
                     T+   +V  P  +GVV  D+N R     EKP   +  S+   TG+Y  + 
Sbjct: 116 DFHKNSGSKVTLVLTRVDIPLEYGVVITDENGRIFKFLEKPSWGEVFSDTVNTGIYIIEP 175

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           ++++   +    ++       +  M LE        +     W D G+    +++   + 
Sbjct: 176 EILDLIPE----DKQFDFSKDLFPMLLEKKIPMYGFVSDN-YWCDIGSGVQYLKSHLDLL 230

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKT 276
                 GFK    E++           +    + L   
Sbjct: 231 RGYVDLGFK----EKVNKDGIIYGKNVIVSENAKLVPP 264


>UniRef50_D1Y1R8 Glucose-1-phosphate thymidylyltransferase n=1 Tax=Pyramidobacter
           piscolens W5455 RepID=D1Y1R8_9BACT
          Length = 295

 Score =  274 bits (703), Expect = 2e-72,   Method: Composition-based stats.
 Identities = 145/287 (50%), Positives = 202/287 (70%), Gaps = 4/287 (1%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           KG+ILA G GTRLHP+T  V+KQL+P+YDKPMIYY + VL+ AG+R+I+++T+  DK  F
Sbjct: 4   KGVILAAGLGTRLHPMTLAVNKQLIPVYDKPMIYYAIWVLIKAGVRDIMLVTSEVDKNSF 63

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLR 121
           +RLLGDGS FGI + Y  Q  P+GL  AF+  E F+ G+P  L+LGDNIF+G GF   L 
Sbjct: 64  ERLLGDGSRFGIHMHYTVQYVPNGLVDAFVQTEDFIAGDPCVLILGDNIFYGSGFPAMLS 123

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVV 181
             +A+ EGATVFG  V DPERFGV  F++  + ++LEEKP  PKSN AV GLYF+D KV+
Sbjct: 124 KASAQMEGATVFGANVPDPERFGVASFNEEGKVLTLEEKPVHPKSNCAVVGLYFFDGKVM 183

Query: 182 EY---AKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +Y    ++  P+++ E+ IT +N++Y+E G L +++  +GFAWLD+GT+DSL+EAS +V 
Sbjct: 184 QYAHELRRQIPADK-EVSITDVNRVYMEQGKLDLQVFPQGFAWLDSGTYDSLLEASNYVA 242

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLEL 285
            VE+ QG  I C EE A+  G+L  E ++    +     YG+YL +L
Sbjct: 243 RVEREQGHMICCPEEAAYSAGFLALEKLREYGEADKNNNYGRYLTKL 289


>UniRef50_B3LAG9 Mannose-1-phosphate guanyltransferase, putative n=3 Tax=Plasmodium
           RepID=B3LAG9_PLAKH
          Length = 434

 Score =  274 bits (703), Expect = 2e-72,   Method: Composition-based stats.
 Identities = 64/285 (22%), Positives = 112/285 (39%), Gaps = 12/285 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M  +IL GG GTRL P+T    K L+   +KP++ + +  L   GIREI++    +    
Sbjct: 1   MNALILVGGYGTRLRPLTLTTPKPLISFCNKPILEHQIFNLARCGIREIILAIAYKPTDI 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
              +     ++ +++ Y+ +  P G      + E +L+      V   +I         +
Sbjct: 61  TNFVDNLEKKYNVKIIYSIEEEPLGTGGPIKLAEKYLSKYDDFFVFNSDIICSFPLLEMM 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                     T+   +V DP  FGVV  ++N R    EEKP+ PKS+    G+Y  + KV
Sbjct: 121 SFHKQSNAPLTILVKEVEDPRAFGVVITEEN-RITKFEEKPQVPKSSLINAGIYIMNRKV 179

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAST-FVQT 239
           +        S   E     I         L   +L +   W D G     ++    +++ 
Sbjct: 180 LNRIPMRNTSLEKE-----IFPQLANENMLYFYVLNK--FWADIGKPMDFLKGQALYMED 232

Query: 240 VEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLE 284
           +++ +G  I    EI      +D   V        ++    + L 
Sbjct: 233 LKENRGKGIEEKREIDKE---IDTAKVSATKPFKEESILRDHFLI 274


>UniRef50_C0E9C6 Putative uncharacterized protein n=1 Tax=Clostridium methylpentosum
           DSM 5476 RepID=C0E9C6_9CLOT
          Length = 768

 Score =  274 bits (702), Expect = 2e-72,   Method: Composition-based stats.
 Identities = 58/281 (20%), Positives = 104/281 (37%), Gaps = 18/281 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +I+AGG G+RL P+T  + K L P+  +P++ Y L +L        ++    +    
Sbjct: 1   MQAVIMAGGEGSRLRPLTCDIPKPLAPLCGRPVLEYILDLLAEHRFDRAVMTLLYQGNKI 60

Query: 61  FQRLLGDGSEF-GIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK 119
                 DG ++ GI+L Y+ +P P G A +        +     LV+  +       +  
Sbjct: 61  ISHF--DGEDYKGIELSYSFEPQPLGTAGSVRHAVK--DPRDDILVISGDALCDFDLTKA 116

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYD 177
           +         AT+   +V DP  +G+V   +N R     EKP      ++ A TG+Y   
Sbjct: 117 VAFHRQSRAAATLLVKRVEDPREYGLVNVTENGRIAGFLEKPSLSHCVTDLANTGIYILS 176

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
             V +  ++ K  +  +     +    LE              W D G   S +     +
Sbjct: 177 PAVFDLIEEGKKVDFAQ----QVFPKMLEKKMPLYAY-EDAGYWCDIGDLQSYVNCQRDM 231

Query: 238 QTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
              + R      C  +     G      +  A  ++    Y
Sbjct: 232 LQGKVR------CSIDAPEVGGVFTKTELLSAQGAVRPPAY 266


>UniRef50_C6A0S3 Nucleotidyl transferase family n=6 Tax=Thermococcaceae
           RepID=C6A0S3_THESM
          Length = 361

 Score =  273 bits (700), Expect = 4e-72,   Method: Composition-based stats.
 Identities = 61/240 (25%), Positives = 108/240 (45%), Gaps = 11/240 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M  +ILAGG GTRL P+T    K ++P ++KPM+ Y +  L+ AG+ EI I+     +  
Sbjct: 1   MHAVILAGGKGTRLLPLTVYRPKPMIPFFNKPMMEYVVRELVNAGVEEIFILVGYLKERI 60

Query: 61  FQRLLGDGSEFGIQLEYAE-QPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK 119
                GDGS+FG++++Y+  +    G A A       +N   + +V   ++         
Sbjct: 61  I-NYFGDGSDFGVEIKYSNGENIKLGTAGATKKVADRIND--TFIVASSDVLTNLDIKTL 117

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYD 177
             +   +   AT+   +V DP ++G+   D N R +  +EKP  ++  SN    G+Y ++
Sbjct: 118 YDYHKRKKALATIALSRVEDPSQYGIAIVDSNNRILKFKEKPRLEEAFSNLVNAGVYIFE 177

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
            +V +   + +          ++    LE              W D G   S ++A+  V
Sbjct: 178 PEVFDLVPRGQ----NFDFSLNLFPKMLEENLPLYGFPFEE-YWNDVGRPSSYLQATADV 232


>UniRef50_O27787 Mannose-1-phosphate guanyltransferase n=1 Tax=Methanothermobacter
           thermautotrophicus str. Delta H RepID=O27787_METTH
          Length = 385

 Score =  273 bits (698), Expect = 7e-72,   Method: Composition-based stats.
 Identities = 56/280 (20%), Positives = 110/280 (39%), Gaps = 14/280 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +++AGG GTR+ P+T    K L+P+ ++P++ Y +  ++ +G  ++++           
Sbjct: 6   VVVMAGGKGTRIRPLTFSRPKPLVPVANRPILDYIIHRVLDSGYSKVVMTLGYLKDQIRS 65

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
            +L +  E  I   ++ +  P G A       + +N   + +VL  ++ F       ++ 
Sbjct: 66  HVLAEYPE--IDFRFSVEKKPLGTAGGVKAAASEIN--ETFIVLSGDVIFDLDLREMVKF 121

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEK--PKQPKSNWAVTGLYFYDSKV 180
              +    TV    V DP  +G+   DD+ +     EK  P++  S  A  G+Y  + +V
Sbjct: 122 HRKKNALVTVALTPVEDPSHYGIAVLDDDGKIKRFHEKPRPEEVFSKIANAGIYVMEPEV 181

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           +E+  Q             I  + +E        L     W D G  ++ + A+  V   
Sbjct: 182 IEHIPQ-----GSSDFSADIFPVLIERDAGMYGFL-FDGYWNDAGKPNTFLRANHDVLNG 235

Query: 241 EKRQGFKIACLEEIAWRNG--WLDDEGVKRAASSLAKTGY 278
                      EE+  R G  W+  + V      +     
Sbjct: 236 TVTPEPDGEIAEEVPGRFGKIWIGRDVVIGDRVRIVGPAV 275


>UniRef50_D1JGY1 Putative bifunctional protein glmU n=1 Tax=uncultured archaeon
           RepID=D1JGY1_9ARCH
          Length = 415

 Score =  272 bits (697), Expect = 8e-72,   Method: Composition-based stats.
 Identities = 68/279 (24%), Positives = 115/279 (41%), Gaps = 11/279 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +ILA G G R+ P+T    K +LPI  KP+I + L  +   GI + + +    D+  
Sbjct: 15  MKALILAAGEGKRMRPLTYERPKVMLPIAGKPIIEHLLEEVKEVGIDDFIFVVGYHDET- 73

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDN-IFFGQGFSPK 119
            +   G+G  + I LEY  Q +  G A A    E  +  +   L+L  + I   +     
Sbjct: 74  IRDYFGNGERWDINLEYVTQKTQLGTADALRKAEELVENQ--FLMLNGDTIVSAKDIKKV 131

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSK 179
           +           +   +V +PE +GVVE +   R   + EK + P SN    G+Y  D  
Sbjct: 132 IN----NGVNMVLGVIEVENPEDYGVVETEGE-RITEIHEKMRVPISNLVNAGVYALDKS 186

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           +     +   S+RGE E+T   Q+ +E+G   +        WLD      L+ A+ F+  
Sbjct: 187 IFGVLSKTDKSKRGEFELTDSLQLLIESGEAILWEKIEH--WLDLSYPWDLLTANEFLIG 244

Query: 240 VEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
                         I      + +  V ++ + +    +
Sbjct: 245 NISPLNRGEVEENVIIGGKVSIGEGTVIKSGTYIEGPAF 283


>UniRef50_A6CNU8 Mannose-1-phosphate guanyltransferase (Pyrophosphorylase domain and
           phosphomannomutase domain) n=1 Tax=Bacillus sp. SG-1
           RepID=A6CNU8_9BACI
          Length = 345

 Score =  272 bits (697), Expect = 9e-72,   Method: Composition-based stats.
 Identities = 65/256 (25%), Positives = 106/256 (41%), Gaps = 10/256 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+ILAGG GTRL P T  V K ++ I +KP++ Y +++L   GI  I+I T  +    
Sbjct: 1   MKGVILAGGKGTRLKPYTLTVPKPMVTIMNKPILEYNIALLKANGITSIMITTCYKA-DK 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                GDGSEFG+ + Y  +  P G A        +LN     +V+  + F        +
Sbjct: 60  ISEYFGDGSEFGVDITYFHEDFPLGTAGGVFESSHYLN--EPFVVISGDAFTTLSLRDAI 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
                +    T+ G ++ DP  +GV + D   R I   EKP+  +  S    TG+Y    
Sbjct: 118 EFHQLKGSPLTIVGKEMEDPRGYGVCKTDSEGRLIEFAEKPESGEINSKLVNTGIYVIQP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +++       P E        +    +   +    +      W D G  +    A     
Sbjct: 178 ELLRKY----PFEGNIDFSRDVFPRMIREQDNI-YVFETEDYWRDIGNPEQYKLAREDYL 232

Query: 239 TVEKRQGFKIACLEEI 254
             + ++      +EE+
Sbjct: 233 NGKMKEKAGADSIEEV 248


>UniRef50_Q8DLP2 Mannose-1-phosphate guanyltransferase n=9 Tax=Cyanobacteria
           RepID=Q8DLP2_THEEB
          Length = 843

 Score =  272 bits (697), Expect = 1e-71,   Method: Composition-based stats.
 Identities = 56/281 (19%), Positives = 108/281 (38%), Gaps = 15/281 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +++AGGSGTRL P+T  + K ++P+ ++P+  + L++L    + ++++ T       
Sbjct: 1   MRVVVMAGGSGTRLRPLTCDLPKPMVPVVNRPIAEHILNLLRRHNLDDVVM-TLHYLPDV 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPS-PDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK 119
            +   GDG+EFG+ L Y  +   P G A +       L      LV+  +       +  
Sbjct: 60  VRDYFGDGNEFGVHLSYVVEEEQPLGTAGSVKNIVNLLTD--PFLVVSGDSITDVDLTDA 117

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYD 177
           LR         T+   +V  P+ FG+V  D + R     EKP   +  ++   TG+Y  +
Sbjct: 118 LRFHQQHGAPVTLILARVPQPKEFGIVFTDSDGRVRRFLEKPSAAEVFTDTVNTGIYILN 177

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
             V++Y       +        +  + L+A       +     W D G+  +  +     
Sbjct: 178 PTVMDYLNSGIERD----FSRDLFPLLLQADVPMYGYI-TDAYWCDVGSLQTYQQVQQDA 232

Query: 238 QTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
                    +   ++       W+           L     
Sbjct: 233 LYGRVHLEIQGHEVQ----PQIWVGHNTPLPPTVQLQAPLV 269


>UniRef50_O29921 Glucose-1-phosphate thymidylyltransferase (GraD-2) n=1
           Tax=Archaeoglobus fulgidus RepID=O29921_ARCFU
          Length = 352

 Score =  272 bits (696), Expect = 1e-71,   Method: Composition-based stats.
 Identities = 93/308 (30%), Positives = 144/308 (46%), Gaps = 18/308 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG++L GG+GTRL P+T    KQL+P+ +KP+  Y L  ++ AGI+E+ II        
Sbjct: 1   MKGVLLHGGAGTRLRPLTFTGPKQLIPVANKPVSQYCLEDMIGAGIKEVAIILGETYPEM 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDGS FG ++ Y  Q  P G+A A  + + F+  E   + LGDN+    G    +
Sbjct: 61  VEEHYGDGSRFGCKITYIHQGKPLGIAHAVYLAKDFVGDEKFVVYLGDNLIQD-GIKEYV 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           +        A +   +V DP  FGV +F+   R + L EKPK+P SN+AV G+Y +   V
Sbjct: 120 KRFDEEDFDAFILLKEVEDPRAFGVAKFEGE-RLVGLIEKPKEPPSNYAVIGVYMFKPVV 178

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            +  K +KPS RGELEIT   Q  +E G        +   W DTG  + +++ +  +   
Sbjct: 179 FDIIKDLKPSWRGELEITDTLQKMIENGYNVGYAKLK-GWWFDTGKAEDILKVNATILDE 237

Query: 241 EKRQGFKIACL-----------EEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLE----L 285
             ++  K   L           E     N  +    V      +  +  G Y       +
Sbjct: 238 RAKRSVKGEVLASQIEGRVEVGEGAKITNSIVRGPAVIGEDCIIENSFIGPYTSVGERTV 297

Query: 286 LRARPRQY 293
           ++    +Y
Sbjct: 298 IKNSSLEY 305


>UniRef50_Q0W4J0 Glucose-1-phosphate thymidylyltransferase n=2 Tax=Euryarchaeota
           RepID=Q0W4J0_UNCMA
          Length = 400

 Score =  271 bits (694), Expect = 2e-71,   Method: Composition-based stats.
 Identities = 65/279 (23%), Positives = 120/279 (43%), Gaps = 10/279 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++LA G G+RL P T    K ++P+ +KP++ Y ++ L  +GI +I+++   + +  
Sbjct: 1   MKAVVLAAGEGSRLKPFTATRPKVMIPVGNKPILEYVINALQESGIIDIVMVVGYK-REK 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQG-FSPK 119
                GDG ++G+ + Y EQ    G A A       +      LV+  +           
Sbjct: 60  IMDYFGDGHKWGVNITYVEQFQQLGTAHALRQASHLIKDH--FLVINGDTVIDASAIKEI 117

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPK-SNWAVTGLYFYDS 178
           +++   +   AT+    V   + +GVVE   N     +EEKPK  +  N    G+Y +  
Sbjct: 118 IKY---KVGDATMLTVSVDKAQAYGVVET-QNNLVKGIEEKPKYKEAGNIVNAGVYCFSP 173

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           KV ++ + +  SERGE E+T   +  +E+      +      W+D     +LI+ +    
Sbjct: 174 KVFDFLEYMDISERGEYEVTDAIRKMIESNYSVRAV-HTSALWMDAVYLWNLIDLNAATL 232

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTG 277
              K +               ++ +  V R+ S +    
Sbjct: 233 AGRKPENHGTVEEGARILGPVYIGENTVIRSGSYIVGPV 271


>UniRef50_Q9ZAE7 Glucose-1-phosphate thymidylyltransferase n=12 Tax=cellular
           organisms RepID=ACBA_ACTS5
          Length = 303

 Score =  271 bits (694), Expect = 2e-71,   Method: Composition-based stats.
 Identities = 155/290 (53%), Positives = 201/290 (69%), Gaps = 1/290 (0%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+GI+LAGG+G+RL P+T  VSKQL+P+YDKPMIYYPL+ L+  GIREIL+ITT  +   
Sbjct: 1   MRGILLAGGTGSRLRPVTWAVSKQLMPVYDKPMIYYPLATLVSCGIREILVITTETEAAQ 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           FQRLLGDGS++G++LE+A Q  P G+A+AF+IGE FL G P  L+LGDN+  G  F P +
Sbjct: 61  FQRLLGDGSQWGLRLEFAVQQRPGGIAEAFLIGEEFLAGGPVALMLGDNLLHGVDFRPCV 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           +       G  VFG  V DP  +GVVEFD   R +S+EEKP +P+S +AV G Y YD+ V
Sbjct: 121 QRARET-AGGHVFGVAVADPSAYGVVEFDAAGRVLSIEEKPVRPRSPYAVPGFYLYDADV 179

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           VE A+ ++PS RGELEIT +NQ YL  G L+V LLGRG  WLDTGT    + A  +V+ +
Sbjct: 180 VETARSLRPSARGELEITEVNQAYLRRGALSVTLLGRGAVWLDTGTLADCMRAVDYVRAI 239

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRARP 290
           ++ QG KI C+EE AWR G+LD   ++  A  L  +GYGQYLL L     
Sbjct: 240 DEGQGIKIGCVEEAAWRAGFLDTAQLRALAEPLMSSGYGQYLLALTGDGL 289


>UniRef50_B8LVX3 Mannose-1-phosphate guanylyltransferase n=2 Tax=Leotiomyceta
           RepID=B8LVX3_TALSN
          Length = 741

 Score =  270 bits (692), Expect = 3e-71,   Method: Composition-based stats.
 Identities = 57/277 (20%), Positives = 104/277 (37%), Gaps = 13/277 (4%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +IL GG GTRL P+T  + K L+   ++PMI + +  L  AG+ +I++          Q
Sbjct: 380 ALILVGGFGTRLRPLTLTLPKPLVEFGNRPMILHQVESLAAAGVTDIVLAVNYRPDIMVQ 439

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLN-GEPSCLVLGDNIFFGQGFSPKLR 121
            L     ++ I +E++ +  P G A    + E  L   +    VL  ++     F     
Sbjct: 440 ALKKYEEQYNINIEFSVESEPLGTAGPLKLAEKILGKDDSPFFVLNSDVICEYPFKQLAE 499

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNF--RAISLEEKPKQPKSNWAVTGLYFYDSK 179
              A  +  T+   +V +P ++GVV    N   R     EKP +   N    G+Y  +  
Sbjct: 500 FHKAHGDEGTIVVTKVDEPSKYGVVVHKPNHPSRIDRFVEKPVEFVGNRINAGIYILNPS 559

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           V++  +    S   E          ++ G L          W+D G     +  +    T
Sbjct: 560 VLKRIELRPTSIEQE-----TFPAIVKEGQL--HSFDLEGFWMDVGQPKDFLSGTCLYLT 612

Query: 240 VEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKT 276
              ++  K+       +         +   ++ + K 
Sbjct: 613 SLAKRNSKLLSPSSEPY---VYGGNVMVDPSAKIGKN 646


>UniRef50_Q1ASA7 Nucleotidyl transferase n=1 Tax=Rubrobacter xylanophilus DSM 9941
           RepID=Q1ASA7_RUBXD
          Length = 346

 Score =  270 bits (692), Expect = 3e-71,   Method: Composition-based stats.
 Identities = 59/277 (21%), Positives = 107/277 (38%), Gaps = 13/277 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK + LA G GTRL P+T  V K + P+ + P+I +  ++L   G+R++ +         
Sbjct: 1   MKAMALAAGKGTRLFPLTGEVPKPMAPVVNTPIIEHIFALLASHGMRKVYVNVHYLADAL 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                      G+++  + +    G A            + + +V+  +          +
Sbjct: 61  LNAYGQTSRINGMEVHLSREERLMGTAGGVKRLADRF--DETFVVVSGDALTDIDLGELV 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEK--PKQPKSNWAVTGLYFYDS 178
                +   AT+   +V D   FGVV+ D        +EK  P++  S  A TG+Y  + 
Sbjct: 119 AFHREKGALATIALKRVYDTSEFGVVDIDAGGNIRGFQEKPPPEEAISTLANTGIYVLEP 178

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           + +EY  +    +        +    LEAG   V   G  F W D GT  +  +A   V 
Sbjct: 179 RALEYIPEDTFFDFA----KDVFPQLLEAGEKFVGYQG-DFYWSDIGTLSAYRQAHYDVL 233

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAK 275
           + + R         E   +  W+ ++     ++S   
Sbjct: 234 SGKVRVRI----PGEKRSKGLWIGEDAKIHPSASFEG 266


>UniRef50_D2PJ00 Glucose-1-phosphate thymidyltransferase n=15 Tax=Archaea
           RepID=D2PJ00_SULIS
          Length = 346

 Score =  270 bits (692), Expect = 4e-71,   Method: Composition-based stats.
 Identities = 84/278 (30%), Positives = 133/278 (47%), Gaps = 7/278 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +IL GG GTRL P+T    KQL+ I  KP+  + L  +  AGI++I+II    +   
Sbjct: 1   MQAVILHGGQGTRLRPLTHTGPKQLIKIAGKPVSQWVLEQIRDAGIKDIIIILGDNNPNK 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                G+GS FG+ + Y  Q    GLA A    +  +  +   + LGDNI         L
Sbjct: 61  VVEYYGEGSRFGVNVTYVYQGKARGLADAVYKVKDVITEDRFLVYLGDNIVPYDNLPSFL 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                    A++   +V +P RFGV     + + I L EKPK+  S+ A+ G+Y +  ++
Sbjct: 121 SF----KGSASILLAKVDNPNRFGVAII-KDGKVIRLVEKPKEKISDSALVGVYAFTREI 175

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            E  + +KPS RGELEIT   Q  ++ G   VE       W DTGT   ++EA++F+   
Sbjct: 176 FEVIENLKPSWRGELEITDAIQGLIDRGRE-VEYKIIDGWWKDTGTPKDILEANSFLLDK 234

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
              +  +    E       +++ E +   ++ +    Y
Sbjct: 235 YAERKIEGEVRESSIDGRVFIEKEALIENST-IRGPAY 271


>UniRef50_Q8TWY9 Nucleoside-diphosphate-sugar pyrophosphorylase involved in
           lipopolysaccharide biosynthesis; translation initiation
           factor eIF2B subunit n=1 Tax=Methanopyrus kandleri
           RepID=Q8TWY9_METKA
          Length = 425

 Score =  270 bits (691), Expect = 5e-71,   Method: Composition-based stats.
 Identities = 71/298 (23%), Positives = 131/298 (43%), Gaps = 15/298 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M GI+LA G GTR+ P+T+   K LLP+ D+ +I + +  +   G+  ++++        
Sbjct: 1   MIGIVLAAGEGTRMRPLTKTRPKVLLPVADRRLIDFSIEAMKRIGVEHLVVVVEY-LAEK 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +R + D      +LE+  Q  P G A A  +    +  + + ++   ++ F        
Sbjct: 60  VERYVKDRWGDSFELEFVRQGKPLGTAHAVYVAWREIEPDETVVITNGDLVFDSELLE-- 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEE--KPKQPKSNWAVTGLYFYDS 178
           R V      A++   +V DP  FGV     +   + L E  KP++  SN A  G+Y  + 
Sbjct: 118 RAVREHEGVASMVLVEVEDPSEFGVARL-QDGYVVELVEKPKPEEAPSNLANAGVYVAEP 176

Query: 179 KVVEYAKQVKPSERGELEITS-INQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTF- 236
           +   + ++VKPS RGE EIT  +    ++ G L +        W D G    L++A+ + 
Sbjct: 177 EFERFLERVKPSPRGEFEITDALLDAAIDEGVLGISY---DGFWSDVGRPWDLLDANAWA 233

Query: 237 VQTVEKRQGFKIACLEEIAWRN-GWLDDEGVKRAASSLAKTGYGQYLLELLRARPRQY 293
           ++    R   +    E +  R   W+ ++ + R+ + +       Y+       P  Y
Sbjct: 234 LRNAMSRPEVEGVIEENVELRGPVWVAEDAILRSGAVVEGPA---YIGPGCEIGPNCY 288


>UniRef50_A6Q9R9 Mannose-1-phosphate guanylyltransferase n=3 Tax=Bacteria
           RepID=A6Q9R9_SULNB
          Length = 840

 Score =  269 bits (689), Expect = 8e-71,   Method: Composition-based stats.
 Identities = 65/291 (22%), Positives = 120/291 (41%), Gaps = 10/291 (3%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K +++AGG GTR+ P+T  + K +LPI + PM+ + +  L+  GI EI+++         
Sbjct: 6   KAVMMAGGFGTRIQPLTHSMPKPMLPICNIPMMEHTMRKLVDIGITEIVVLL-YFKPEII 64

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLR 121
           +   GDGS  G++LEY       G A A      FL  + + +++  ++     F   + 
Sbjct: 65  KNHFGDGSRIGVKLEYVLPEEDLGTAGAVGAAREFL--DTTFIIVSGDLVSDFDFEKIID 122

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDSK 179
           H        T+    V +P +FGVV  D+N +     EKP   +  S+   TG+Y  + +
Sbjct: 123 HHYKTESKLTITLTSVENPLQFGVVIADENGKIEKFLEKPSWGEVFSDTINTGIYVIEPE 182

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           +++Y     P+E        +  + +  G   +        W D G  DS  E    +  
Sbjct: 183 ILDYI----PTEDNFDFAKDLFPLLMSEGIDLMSY-DARGYWRDVGNPDSYREVYGDIFK 237

Query: 240 VEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRARP 290
            + +  F    +E         ++  +  +   +     G ++      R 
Sbjct: 238 QKIKVAFPGKKIEYPDGVLYLGEESEIDPSVEIIDTVIIGSHVQIGKNVRL 288


>UniRef50_Q9KD03 Mannose-1-phosphate guanyltransferase n=1 Tax=Bacillus halodurans
           RepID=Q9KD03_BACHD
          Length = 249

 Score =  269 bits (688), Expect = 9e-71,   Method: Composition-based stats.
 Identities = 63/241 (26%), Positives = 114/241 (47%), Gaps = 10/241 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+ILAGG GTRL P+T  + K +LPI   P + + L+ L   GIR+I+++        
Sbjct: 1   MKGVILAGGRGTRLKPLTDQIPKPMLPIAGVPCLAHGLAHLAAHGIRDIVMLVHY-LNHQ 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +    DGS++G+++ Y ++ +P G A +    E +L  +   +V+  ++         +
Sbjct: 60  MKAYFQDGSKYGMRITYVQEDAPLGTAGSLKAAERYL--DEPFVVMSGDVLTTISIQEAI 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSN--WAVTGLYFYDS 178
                +    T+   +V + + +GVV+   N R ++  EKP + K+      TGLY  D 
Sbjct: 118 VFHKRQNSLMTMLTKRVKNGQNYGVVQTGPNHRVVAFREKPTEDKTREVLVNTGLYVMDP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
            V+ Y  +    + G      +    ++   L +  L  G  W D G+    ++A+  V 
Sbjct: 178 FVLSYIPKGSAVDLG----KDVIPYLVDR-KLDIFALEGGGYWRDIGSFHDYLQANNDVN 232

Query: 239 T 239
           +
Sbjct: 233 S 233


>UniRef50_A7GF11 Glucose-1-phosphate thymidylyltransferase n=9 Tax=Clostridium
           botulinum RepID=A7GF11_CLOBL
          Length = 353

 Score =  268 bits (687), Expect = 1e-70,   Method: Composition-based stats.
 Identities = 82/280 (29%), Positives = 142/280 (50%), Gaps = 4/280 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +IL+GG+GTRL P+T   +KQLLP+ +KP+++Y +  ++ AGI +I II     +  
Sbjct: 1   MKALILSGGTGTRLRPLTYTNAKQLLPLANKPILFYIIEKIVKAGIYDIGIIVGDTREE- 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            ++++G+G  +G+++ Y  QP+P GLA A      FL  +   +VLGDN+F     +  +
Sbjct: 60  VKKMVGNGDRWGVKISYLYQPAPLGLAHAVKTASEFLMEDDFLMVLGDNVF-NMELNKLI 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
               +    + +  ++V +P ++GV   +D    I L EKPK+  S+  +TG+Y +D  +
Sbjct: 119 DSFYSNNANSALLLHKVENPSQYGVAVVEDT-LIIKLVEKPKEFVSDLIITGVYIFDKSI 177

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
                 +KPS+RGELEIT   Q  LE G      L +   W DTG    ++EA+  +   
Sbjct: 178 FMAIDNIKPSQRGELEITDAIQKQLETGGRVTYELIQ-GWWKDTGQLQDILEANRLMLDE 236

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQ 280
              +   +     +      +    +   ++ +       
Sbjct: 237 IDCEFKTLPQSNSVFMGKIQIGRNVIIENSTIIGPVAIAD 276


>UniRef50_A5D3D6 dTDP-glucose pyrophosphorylase n=5 Tax=Bacteria RepID=A5D3D6_PELTS
          Length = 388

 Score =  268 bits (686), Expect = 2e-70,   Method: Composition-based stats.
 Identities = 92/280 (32%), Positives = 139/280 (49%), Gaps = 8/280 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +K +IL+GG GTRL P+T   +KQL+P+ +KP++ + +  +  AGIR+I +I +PE    
Sbjct: 34  VKALILSGGKGTRLRPLTYTTAKQLIPVANKPILEFVVEQICQAGIRDIGMIISPETGEQ 93

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  +G G  +G ++ Y  Q  P GLA A      FL   P  + LGDN+  G G    +
Sbjct: 94  VKEAIGCGERWGARITYILQEKPAGLAHAVKTARPFLGDSPFLMFLGDNLVQG-GVGQLV 152

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           +  A     A +   +V DP +FGV    +N R I L EKPK+P  N A+ G+Y + S V
Sbjct: 153 KDFAGSRADAMIQLKEVADPSQFGVAVLGENNRVIRLVEKPKEPPGNLALVGIYLFGSAV 212

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
               +++KPS RGELEIT   Q  +  G  +V+       WLDTG  D ++EA+  V   
Sbjct: 213 HRAIERIKPSWRGELEITDAIQEMINLG-CSVDARILDGWWLDTGKKDDILEANRVVLDE 271

Query: 241 EKRQGFKIACLEE------IAWRNGWLDDEGVKRAASSLA 274
             R                ++   G      + R  + + 
Sbjct: 272 YARLEISGTVDRYSRITGRVSIGRGSEVKNSIVRGPAVIG 311


>UniRef50_Q12TW4 Mannose-1-phosphate guanyltransferase n=11 Tax=Euryarchaeota
           RepID=Q12TW4_METBU
          Length = 399

 Score =  266 bits (682), Expect = 4e-70,   Method: Composition-based stats.
 Identities = 66/280 (23%), Positives = 108/280 (38%), Gaps = 11/280 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK  I+ GG GTRL P+T    K  +PI +KP + + +  L   G  EI+I         
Sbjct: 14  MKACIMCGGEGTRLRPLTFERPKPSIPILNKPSVVHLVEHLAKEGFTEIVITIGY-MAEK 72

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  LGDG  +G+ +EY  +    G A      E FL  EP  +V G +           
Sbjct: 73  IEECLGDGRMYGVYIEYVYEEKRLGTAGGVKNAEEFLKDEPFMIV-GGDHVMDLSLRSIY 131

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEK--PKQPKSNWAVTGLYFYDS 178
           R         T+    + DP  FG+ + D N R     EK  P +  SN A TG+Y    
Sbjct: 132 RQHEMNDAMITIGLMSIDDPREFGIADMDVNNRIHRFLEKPGPGEIFSNLASTGIYMCSP 191

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           ++ ++  + +  +        +    +  G     +L R   W D G+  +  +A  ++ 
Sbjct: 192 EIFDWIPKDEKYDFA----KDLFPALMSKGKKINGMLVR-GHWTDVGSSTAYRQAQRWML 246

Query: 239 TVEKRQGFKIACLEEIAWRNGW--LDDEGVKRAASSLAKT 276
                   +     + A   G   + +  +    S+L   
Sbjct: 247 ESLPGTSIEGNFNTKDARIQGPLKIGNNVIVGTNSALVGP 286


>UniRef50_Q97A91 Glucose-1-phosphate thymidylyltransferase n=2 Tax=Thermoplasma
           volcanium RepID=Q97A91_THEVO
          Length = 351

 Score =  266 bits (681), Expect = 6e-70,   Method: Composition-based stats.
 Identities = 86/280 (30%), Positives = 129/280 (46%), Gaps = 7/280 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKGIIL GGSGTRL P+T    KQLLPI  KP+  Y L  L+  GI+ I I+        
Sbjct: 3   MKGIILHGGSGTRLRPLTYTDVKQLLPIAGKPISEYALENLIEIGIKNINIVIGSVGGLE 62

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            ++  GDGS + + + Y  QP P G+A A  + + F+  +   + L  + +   G S   
Sbjct: 63  VKKFYGDGSRWNVNISYTYQPEPLGIAHAIGLTKAFVGNDDFVVFL-GDNYLQNGISNLY 121

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                      +    V +P +FG+ E D N +   L EKPK P SN A+ G+YF   KV
Sbjct: 122 EDFTNAGSDGHLGLVPVDNPSQFGIAEVD-NGKISKLVEKPKTPTSNLAIVGVYFLTPKV 180

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            E   ++KPS+RGE EIT   Q  ++ G      +     + DTGT D  +  +  +   
Sbjct: 181 FESIDRLKPSKRGEYEITEAYQDMIDRGLKISYSII-SGWFKDTGTVDDFLACNRLILDK 239

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQ 280
               G +    + ++ R        +   +  +     G+
Sbjct: 240 LGDNGRR----DNVSGRFDIHPTVKISSDSEVVGPCFIGE 275


>UniRef50_B5GLJ2 NDP-1-glucose synthase n=1 Tax=Streptomyces clavuligerus ATCC 27064
           RepID=B5GLJ2_STRCL
          Length = 359

 Score =  265 bits (679), Expect = 1e-69,   Method: Composition-based stats.
 Identities = 96/304 (31%), Positives = 138/304 (45%), Gaps = 16/304 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++LAGGSG+RL P++  + KQL+P+ +KP++ Y L  +   GI  I ++        
Sbjct: 1   MKALVLAGGSGSRLRPLSNFMPKQLIPVANKPVLEYVLENIRELGITRIGLVVG-GWADT 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  +GDGS FG ++ Y  Q  P GLA A  +   FL  +   + LGDN+    G +P  
Sbjct: 60  IRGAVGDGSRFGAEITYLRQERPAGLAHAVRLARPFLGDDDFAMFLGDNLLPD-GVAPVA 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                    A V  ++V DP  FGVVE D       L EKP +P+S+ A+ G YF+ S V
Sbjct: 119 ADFLRGRPAAQVVVHKVDDPRDFGVVELDAAGGVRRLVEKPSRPRSDLALVGTYFFTSAV 178

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
                 ++PS RGELEIT   Q  LE G  +V     G  W DTG  D L+EA+  V   
Sbjct: 179 HRAVDAIRPSPRGELEITDAIQWLLEDG-ASVGCSEYGGYWKDTGRADDLLEANRRVLEG 237

Query: 241 EKRQGFKIACLEEIAWRNGW------------LDDEGVKRAASSLAKTGYGQYLLELLRA 288
           E   G   +     A                 +    +    + +  +  G +       
Sbjct: 238 ESG-GVAGSVDAASALLGRVRIAPGARVVRSRITGPAIIGPGALVEDSLIGPHTAVGAGC 296

Query: 289 RPRQ 292
           R R 
Sbjct: 297 RLRA 300


>UniRef50_C7IJC3 Glucose-1-phosphate thymidylyltransferase n=1 Tax=Clostridium
           papyrosolvens DSM 2782 RepID=C7IJC3_9CLOT
          Length = 285

 Score =  264 bits (677), Expect = 2e-69,   Method: Composition-based stats.
 Identities = 143/285 (50%), Positives = 194/285 (68%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK IILAGG G+R++P T  +SK L  IYDKPMIYY  S+ ++AGI E+LII   E    
Sbjct: 1   MKAIILAGGKGSRMYPATVAISKHLFLIYDKPMIYYSFSIALMAGINEVLIIAGNEHIEA 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F+ L GDGS  GI +EY  Q  P G+A+AFIIGE F+  +  CL+LGDN F+G  F   L
Sbjct: 61  FRNLFGDGSNLGIHIEYRIQDEPRGIAEAFIIGEKFIGNDSVCLILGDNFFYGDSFVYHL 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           + ++   EGA +F YQ  +PE FGVVEFD+  R +S++EK K   SN+ V G+YFYD+ V
Sbjct: 121 KALSQLKEGAGIFAYQEKNPEEFGVVEFDETGRVLSIKEKSKDSNSNYVVPGVYFYDNHV 180

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           +E AK +KPS+RGELEIT++N +YLE G L VE+L     WLDTG++++L+EAS FV++V
Sbjct: 181 IEVAKSIKPSKRGELEITTVNNVYLEKGKLKVEVLPPDVKWLDTGSYETLLEASNFVKSV 240

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLEL 285
           +   G  I+CLEEI+++N ++    V  AA     T Y +YLL +
Sbjct: 241 QTETGNMISCLEEISYKNRFIGKSEVAMAAEKYKGTQYSEYLLSI 285


>UniRef50_UPI000038E60D glucose-1-phosphate thymidylyltransferase (graD-2) n=1
           Tax=Ferroplasma acidarmanus fer1 RepID=UPI000038E60D
          Length = 351

 Score =  264 bits (677), Expect = 2e-69,   Method: Composition-based stats.
 Identities = 99/293 (33%), Positives = 148/293 (50%), Gaps = 11/293 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKGIIL GG+GTRL P+T    KQL+PI +KPM  Y L  L  AGI +I +I        
Sbjct: 1   MKGIILHGGAGTRLRPLTHTGPKQLIPIANKPMSQYVLEYLTDAGINDICMILGDISPEK 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDGSEF   ++Y +Q +P G+A A  +   F+  +   ++LGDN+  G+     +
Sbjct: 61  VKDYYGDGSEFDCNIQYIDQGAPLGIANAVSLTSNFVGNDKFVVILGDNLIEGK-IKTFM 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                    A +   + M P+ FGV EF DN + I+L EKP+ P SN+ +TG+YF+   +
Sbjct: 120 DKFEKSNYDAFIVLTKSMHPKDFGVAEFRDN-KLINLIEKPENPPSNYVLTGIYFFTPLI 178

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            +Y K++KPS R E EIT   Q+ L+        +     W DTGT D ++ A+  +   
Sbjct: 179 FDYIKKLKPSWRNEYEITEAIQLLLKDNKNIGYDII-DGWWKDTGTVDDILAANMLILDR 237

Query: 241 EKRQGFKIACLEEIA-WRNGWLDDEGVKRAASSLA-------KTGYGQYLLEL 285
            K    +     ++A  +N  L D+ + R  + +        KT  G Y    
Sbjct: 238 GKNIEERANVKGKVAIGKNVVLSDDSLIRGPAIIGDNTVIQDKTFIGPYTSIG 290


>UniRef50_C7XIA2 Glucose-1-phosphate thymidylyltransferase n=1 Tax=Lactobacillus
           crispatus 125-2-CHN RepID=C7XIA2_9LACO
          Length = 270

 Score =  264 bits (676), Expect = 2e-69,   Method: Composition-based stats.
 Identities = 166/291 (57%), Positives = 209/291 (71%), Gaps = 22/291 (7%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKGIILAGGSGTRL+P+T   SKQLLP+YDKPMIYYPLS LMLAGI++ILII+TP D   
Sbjct: 1   MKGIILAGGSGTRLYPLTLVTSKQLLPVYDKPMIYYPLSTLMLAGIKDILIISTPADTPR 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F++LLGDGS+FGI+L Y  QPSPDG AQAF +G+ F+NGEP  ++LGDNIF+G GF+  L
Sbjct: 61  FEKLLGDGSQFGIKLSYKVQPSPDGWAQAFTLGKDFINGEPCAMILGDNIFYGNGFTKLL 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           +  AA                         N +AIS+EEKP+ PKSN+AVTGLYFY + V
Sbjct: 121 KQAAAD----------------------ARNGKAISIEEKPEHPKSNYAVTGLYFYPAGV 158

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            E A QVKPS RGE+EITS+N MYL+ GNL V+LLGRG+AWLD GT  SL++AS +V+ V
Sbjct: 159 SEKAAQVKPSARGEIEITSLNDMYLQEGNLDVQLLGRGYAWLDAGTMQSLVDASNYVKMV 218

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRARPR 291
           E+RQG  I+  EEIA+ +GW+D + +  AA    K+ YGQ+L  +   + R
Sbjct: 219 EERQGVSISAPEEIAYIHGWIDKDKLLDAAKHYGKSPYGQHLKSVAEGKLR 269


>UniRef50_Q8ILP1 Mannose-1-phosphate guanyltransferase, putative n=4 Tax=Plasmodium
           RepID=Q8ILP1_PLAF7
          Length = 408

 Score =  264 bits (676), Expect = 2e-69,   Method: Composition-based stats.
 Identities = 54/247 (21%), Positives = 96/247 (38%), Gaps = 8/247 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M  +IL GG GTRL P+T    K L+   +KP+I + +  L   GI+EI++    +    
Sbjct: 1   MNALILVGGYGTRLRPLTLTTPKPLINFCNKPIIEHQILHLAKCGIKEIILAIAYKPTNI 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
              +     ++ +Q+ ++ +  P G      + E +LN      V   +I         +
Sbjct: 61  TNFVKEMEKKYNVQIIFSVEDEPLGTGGPLKLAENYLNKYDDFFVFNSDIICTFPLIEMM 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                     T+   +V DP  FGVV  +D       EEKP  PKS+    G+Y  + ++
Sbjct: 121 NFHKQNKAPLTILVKEVEDPRAFGVVITEDKM-ITKFEEKPLVPKSSLINAGIYILNKQI 179

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           + +  Q   S   E+     +   L               W D G     ++  +     
Sbjct: 180 LNFIPQRNCSLEKEIFPKLASDNML-------YFYQLNNFWADIGKPLDFLKGQSLYMEN 232

Query: 241 EKRQGFK 247
            + + ++
Sbjct: 233 LEERKYE 239


>UniRef50_C0ZCI7 Probable glucose-1-phosphate thymidylyltransferase n=1
           Tax=Brevibacillus brevis NBRC 100599 RepID=C0ZCI7_BREBN
          Length = 348

 Score =  264 bits (676), Expect = 3e-69,   Method: Composition-based stats.
 Identities = 91/291 (31%), Positives = 137/291 (47%), Gaps = 6/291 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+IL  G GTRLHP +    K LLP+ + P+++Y +  L   GI++I I+  P  +  
Sbjct: 1   MKGLILCAGRGTRLHPFSYSQPKTLLPVANHPVLHYCIRKLREVGIQDIGIVIHP-SQSQ 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
              ++GDGS+FG  + + +Q  P G+A A  + + FL  EP  L+LGDN+          
Sbjct: 60  IPPMVGDGSQFGATITFIKQEVPLGIAHAVQLAQPFLQDEPFILLLGDNLLMD-SLHGLT 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           +          V   +V  P+ +G+ E     R IS+EEKP+QPKSN AV G Y +   +
Sbjct: 119 KAFTKGKSDGVVMLSKVERPQDYGIAEV-QKGRLISVEEKPRQPKSNLAVIGAYLFTPPI 177

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            E    ++PS RGELEIT   Q  +  G      +  G    D GT D  +EA+ ++ T 
Sbjct: 178 FESIATLQPSPRGELEITDAIQSMINRGFKLAHSVTNGKY-SDVGTIDRWLEANQWMLTR 236

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRARPR 291
           E   G +    +    +N  +           +     G Y+        R
Sbjct: 237 E--LGNQHQIGKGTVVKNSKITGPVRIGDDCVIENCQIGPYVSIQNGVSLR 285


>UniRef50_A4I048 Mannose-1-phosphate guanyltransferase n=5 Tax=Leishmania
           RepID=A4I048_LEIIN
          Length = 379

 Score =  264 bits (675), Expect = 3e-69,   Method: Composition-based stats.
 Identities = 59/295 (20%), Positives = 107/295 (36%), Gaps = 15/295 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +IL GG GTRL P+T    K L+P  +KPMI + +  L   G+ E+++      +  
Sbjct: 9   MRAVILVGGFGTRLRPLTLTTPKPLVPFCNKPMIIHQIEALKAVGVTEVILAVAYRPEAM 68

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFL-NGEPSCLVLGDNIFFGQGFSPK 119
            +++     + G+   ++ +  P G A    +    L   +    VL  ++         
Sbjct: 69  KEQMDEWSRKLGVSFVFSVEEEPLGTAGPLALARDILMQDDKPFFVLNSDVTCTFPMQEL 128

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFD-DNFRAISLEEKPKQPKSNWAVTGLYFYDS 178
           L    A     T+   QV   E++GVV +   N++     EKP +   +    G+Y ++ 
Sbjct: 129 LDFHKAHGGEGTIMVSQVTQWEKYGVVVYSPQNYQIERFVEKPSRFLGDRINAGIYIFNK 188

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV- 237
            +++     + S   E     I       G L          W+D G     I   T   
Sbjct: 189 SILDRIPPRRTSIEKE-----IFPAMAAEGQL--YAFNLEGFWMDVGQPKDYILGMTKFI 241

Query: 238 -QTVEKRQGFKIACLEEIAWRNG----WLDDEGVKRAASSLAKTGYGQYLLELLR 287
              V   +  +    E++  + G     +    +  +A        G Y      
Sbjct: 242 PSLVHGNRETEQLHTEDMEHQRGGRFTVIGASLIDPSAKIGDGAVIGPYASIGAN 296


>UniRef50_A7AUL2 Mannose-1-phosphate guanyltransferase, putative n=1 Tax=Babesia
           bovis RepID=A7AUL2_BABBO
          Length = 417

 Score =  263 bits (673), Expect = 5e-69,   Method: Composition-based stats.
 Identities = 57/270 (21%), Positives = 100/270 (37%), Gaps = 11/270 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +ILAGG GTRL P+T  V K ++P  ++P++ Y +     AG+  I++  + E    
Sbjct: 1   MKCVILAGGHGTRLRPLTLTVPKPMIPFCNRPIVEYQIKASKEAGVDHIILAISHEQNNM 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPS----CLVLGDNIFFGQGF 116
              +        I+++ + +    G A    + +  +          LVL  +I     F
Sbjct: 61  VPMIKELSERCNIRIDCSIEKESLGTAGPLKLAKNLICDPADNCKEFLVLNSDIICSYPF 120

Query: 117 SPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFY 176
           +  +         AT+   +   P  FGV+  D+ +R     EKP Q  SN    G+Y  
Sbjct: 121 AEMISAHRKNNADATILVTKTTHPSDFGVIVHDETYRIHEFVEKPSQFISNQINAGIYVL 180

Query: 177 DSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTF 236
           +  +++Y      S         +    +  G            W D G     I A   
Sbjct: 181 NKNMLDYIPDGSVSIE-----RYLFPTMVAMGRTYCH--PLNGLWADIGKPSDYIRAQQL 233

Query: 237 VQTVEKRQGFKIACLEEIAWRNGWLDDEGV 266
             T   +    +    E    + ++ +  V
Sbjct: 234 YLTGRPKDEEIMMLRCEGDSEDDYIKESHV 263


>UniRef50_B0PFA5 Putative uncharacterized protein n=1 Tax=Anaerotruncus colihominis
           DSM 17241 RepID=B0PFA5_9FIRM
          Length = 772

 Score =  263 bits (673), Expect = 6e-69,   Method: Composition-based stats.
 Identities = 60/254 (23%), Positives = 95/254 (37%), Gaps = 10/254 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +I+AGG GTRL P+T    K +  +  +P++ Y L +L   G+ E ++         
Sbjct: 1   MKAVIMAGGRGTRLRPLTERCPKPMARLCGRPVVEYILELLAKNGVTESVLTLQY-LPDQ 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                 D S  GI L + E+  P G A +       +  +   LV+  +          +
Sbjct: 60  IVSHFPDNSFAGIALSFCEEAQPLGTAGSVKNAAGQIGED--LLVISGDALCDFSLREAM 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
              AAR    T+   +V DP  +G+V  D +       EKP   Q  S  A TG+Y    
Sbjct: 118 DQHAARCADVTIVTARVGDPREYGLVIADSDGHVTGFIEKPSFAQATSELANTGIYILSP 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
             VE     +  +        +    LE G + V+       W D G  ++   A   + 
Sbjct: 178 HAVEMIPDGQIFDFA----ADLFPRMLEKG-MAVDCCTLSGYWCDIGDLEAYRRAQADLL 232

Query: 239 TVEKRQGFKIACLE 252
                   +    E
Sbjct: 233 AGRVDATLRGQRDE 246


>UniRef50_C8NLU6 Mannose-1-phosphate guanyltransferase n=88 Tax=Actinomycetales
           RepID=C8NLU6_COREF
          Length = 372

 Score =  262 bits (670), Expect = 1e-68,   Method: Composition-based stats.
 Identities = 59/281 (20%), Positives = 109/281 (38%), Gaps = 14/281 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +  +IL GG GTRL P+T    K +LP    P + + L+ +  AGI  +++ T+ + +  
Sbjct: 20  VDAVILVGGKGTRLRPLTNNTPKPMLPTAGHPFLKHLLARIKAAGITHVVLGTSFKAE-V 78

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F+   GDGS+ G+++EY  +  P G           L    + +V   ++  G      L
Sbjct: 79  FEDYFGDGSDLGLEIEYVVEDQPLGTGGGIRNVYDKLR-HDTAVVFNGDVLSGADLGDIL 137

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                +    T+   +V +P  FG V  D + R +   EK + P ++    G Y +  ++
Sbjct: 138 ATHREKEADLTMHLVRVANPRAFGCVPTDADGRVLEFLEKTEDPPTDQINAGCYVFQREL 197

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT- 239
           +       P++R            L+ G      +     W D GT    +  S+ +   
Sbjct: 198 IASI----PADRVVSVERETFPQLLQEGRRVYGHVDTS-YWRDMGTPQDFVRGSSDLVRG 252

Query: 240 ------VEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLA 274
                 +E + G ++            L    V    + + 
Sbjct: 253 IAFSPLLEGQTGEELVDPSAGVRDGVILLGGTVVGRGTEIG 293


>UniRef50_A6UP85 Glucosamine-1-phosphate N-acetyltransferase n=6 Tax=Methanococcales
           RepID=GLMU_METVS
          Length = 414

 Score =  261 bits (668), Expect = 2e-68,   Method: Composition-based stats.
 Identities = 69/300 (23%), Positives = 128/300 (42%), Gaps = 27/300 (9%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M  +IL  GSGTRL+PIT    K ++PI  KP++ + +  +    + +I ++   E +  
Sbjct: 1   MDAVILCAGSGTRLYPITENRPKPMIPIAGKPILEHIIEKIENH-VEKIYLVVGFEKEKI 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                G+      ++E+  Q    G   A ++ + ++ G+   LVL  ++ F       L
Sbjct: 60  IDYFYGNE-----KIEFIVQEKQLGTGHAVLMAKNYIKGD--FLVLNGDVIFESDILEFL 112

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPK------SNWAVTGLY 174
            +         V   +V +PE FGV+E   + + I+L EKP + +      SN    G+Y
Sbjct: 113 NY------ENAVGLSKVDNPENFGVIELGYDNKVINLLEKPNEDEIKSKFTSNLINAGIY 166

Query: 175 FYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
             ++ V E  + + PSERGE+E+T   +  +E+  L    +     W D G    ++ A+
Sbjct: 167 KLENFVFEILENLLPSERGEIELTDALKKLIESSKL--YGIELNGYWNDIGRPWDVLSAN 224

Query: 235 TFVQ-TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRARPRQY 293
            +    +  +    I     I   N  +++    ++ S +        +       P  Y
Sbjct: 225 NYFLKNIMPKISGNIENNVTITG-NVIIEEGVTVKSNSVIEGPVI---IKSGAFIGPLAY 280


>UniRef50_Q74B34 Nucleotidyltransferase family protein n=1 Tax=Geobacter
           sulfurreducens RepID=Q74B34_GEOSL
          Length = 476

 Score =  261 bits (668), Expect = 2e-68,   Method: Composition-based stats.
 Identities = 64/239 (26%), Positives = 105/239 (43%), Gaps = 13/239 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +++AGG G RL P+T  V K +LP+ D+P++   +  L  +GIRE+ + T        +
Sbjct: 249 AVVMAGGYGKRLLPLTEQVPKPMLPVGDRPLLERTIDQLRRSGIREVNLTTHYLPDSIVE 308

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
              GDG  FG++L Y ++  P G A    + +         LV+  +I  G  F     +
Sbjct: 309 -HFGDGDSFGVKLNYLKEDHPLGTAGGLKLMKKA---SDPFLVMNGDILTGVPFQEMFAY 364

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
                   TV   +      FGVVE DD  R   L+EKP    + +   G+Y  +  V +
Sbjct: 365 HRKNGAEITVGVRKYEVQVPFGVVECDDV-RITGLKEKPS--LTFFINAGIYLLEPSVCD 421

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVE 241
              + +       ++T + Q  L+ G   V        WLD G H+   +A   V++ +
Sbjct: 422 LIPEGER-----FDMTDLIQKLLDEGRSVVSFPIME-YWLDVGRHEDYQKAQEDVRSGK 474


>UniRef50_UPI000186E54F Mannose-1-phosphate guanyltransferase, putative n=1 Tax=Pediculus
           humanus corporis RepID=UPI000186E54F
          Length = 348

 Score =  261 bits (667), Expect = 3e-68,   Method: Composition-based stats.
 Identities = 66/288 (22%), Positives = 108/288 (37%), Gaps = 16/288 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +IL GG GTRL P+T    K L+   +KPM+ + +  L+ AG+ EI++  +   +  
Sbjct: 12  MKALILVGGYGTRLRPLTLSRPKPLVEFANKPMLIHQIEALVDAGVTEIVLAVSYRAQQM 71

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLN-GEPSCLVLGDNIFFGQGFSPK 119
            + L    +  G+ L ++E+  P G A    +    L        VL  +I     F   
Sbjct: 72  EKELTERAANLGVTLIFSEESEPLGTAGPLALAREILGTSSEPFFVLNSDIICDFPFKEM 131

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSK 179
                   +  T+   +V +P ++GVV + +  +  S  EKP++  SN    G+Y     
Sbjct: 132 YEFHKNHGKEGTIVVTKVDEPSKYGVVVYGEEGKVESFIEKPQEFVSNKINAGMYILSPS 191

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTG-THDSLIEASTFVQ 238
           V++       S   E         +L      V      +   D G    SL      V 
Sbjct: 192 VLKRIALKPTSIENEF-----FPKWL----PMVNYSLSNY--KDFGWIPQSLSTREGIVG 240

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKT--GYGQYLLE 284
            V      KI     I   N  +    V      + ++    G Y+  
Sbjct: 241 NVLVDSTAKIGHGCRI-GPNVIIGPNVVIENGVCIRRSTILEGSYVKS 287


>UniRef50_C6A1S5 NDP-sugar synthase n=9 Tax=Thermococcaceae RepID=C6A1S5_THESM
          Length = 413

 Score =  261 bits (667), Expect = 3e-68,   Method: Composition-based stats.
 Identities = 66/282 (23%), Positives = 116/282 (41%), Gaps = 24/282 (8%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLML-AGIREILIITTPEDKG 59
           MK +ILAGG GTRL P++    K ++P+  +P + Y L  L   + I E+++        
Sbjct: 1   MKAVILAGGFGTRLRPLSSTRPKPMIPVLGRPNLQYILENLQKISEIDEVILSVHYMRGE 60

Query: 60  YFQRLLGDG-SEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSP 118
             +  + D  S++   + +   P P     A    E  ++ E   LV+  ++F    F  
Sbjct: 61  -IREFIEDKMSDYPKDIRFINDPMPLETGGALKNVEDVVSDE--FLVIYGDVFTNFNFEE 117

Query: 119 KLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDS 178
            ++   A     TV   +V DPE++GVV  D+  + +  EEKP +PKSN    G+Y  + 
Sbjct: 118 LIKAHKANDALITVALTKVYDPEKYGVVVTDEEGKIVDFEEKPLRPKSNLIDAGIYMVNK 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +++    + K           +   ++  G     ++ R   W+D GT +    A   + 
Sbjct: 178 EILNEIPKGK----EIYFEREVLPKFVAQGLAHGYMMPRNNYWVDLGTPEDFFYAHQLIL 233

Query: 239 TVEKRQGFKIACLEEIAWRNGWLD--DEGVKRAASSLAKTGY 278
                        +EIA  NG+    +         +    Y
Sbjct: 234 -------------DEIAKNNGYYTVKEGTEVPEDVEIQGPVY 262


>UniRef50_Q46AY5 Glucose-1-phosphate thymidylyltransferase n=4
           Tax=Methanosarcinaceae RepID=Q46AY5_METBF
          Length = 405

 Score =  260 bits (666), Expect = 3e-68,   Method: Composition-based stats.
 Identities = 67/281 (23%), Positives = 121/281 (43%), Gaps = 9/281 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK IILA G G R  P+T   SK +LPI ++P++ + +  L   GI +I++I   + +  
Sbjct: 1   MKAIILAAGEGLRCRPLTLTRSKVMLPIANRPILEHVIGSLEKNGITDIILIVGYKKE-R 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPS-CLVLGDNIFFG-QGFSP 118
                 DG  FG++++Y EQ +  G A A    + ++  E S  LVL  +     +  + 
Sbjct: 60  IMDYFEDGLNFGVKIKYVEQKAQLGTAHAIEQAKKWIEPEDSEFLVLNGDNLVEPKTIAD 119

Query: 119 KLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDS 178
            L +       A++   Q+ +   +GVV   +  R   + EK     S    TG+Y +  
Sbjct: 120 LLNNYE---GDASLLTVQMEETAGYGVV-LKEKKRVTRILEKRPGDLSRIVNTGIYIFTP 175

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           +V E  ++   SE GE  IT   Q+ ++ G +   +  +   W+D      L++A+  V 
Sbjct: 176 QVFETIEKTPISENGEYAITDTLQLMIDEGKIVTSVSTKS-KWIDAVHSWDLLKANAIVL 234

Query: 239 TVEKRQGFKIACLEEIAWRNGW-LDDEGVKRAASSLAKTGY 278
              +    +    E +       +      R+ + +     
Sbjct: 235 NSARNLKLEGEVEEGVFLSGKVAVGKNTRIRSGTYIVGPVV 275


>UniRef50_Q67QD8 Putative mannose-1-phosphate guanyltransferase n=1
           Tax=Symbiobacterium thermophilum RepID=Q67QD8_SYMTH
          Length = 343

 Score =  260 bits (665), Expect = 4e-68,   Method: Composition-based stats.
 Identities = 66/299 (22%), Positives = 108/299 (36%), Gaps = 21/299 (7%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           ++ I+LAGG GTRLHP+T  + K ++P+  KP +   +  L   G+ +I +         
Sbjct: 3   VRAILLAGGLGTRLHPLTVELPKPMVPVLGKPWLSRLIDQLAAFGVTDITLSLRH-GGQV 61

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEP--SCLVLGDNIFFGQGFSP 118
                 + S  G++L +A +P P G   A          +P  + L+L  +I      + 
Sbjct: 62  VTDYFRE-SPPGVRLRFAVEPQPLGTGGAIRFAA---GPDPTDTLLILNADIVQTFDLNA 117

Query: 119 KLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFY 176
            L          T+   +V DP  +G VE D N R     EKP+  +  S     G+Y +
Sbjct: 118 LLEFHRQHRAQVTIGLVEVADPSAYGAVELDKNSRVTRFVEKPRPGETDSRMVNAGVYVF 177

Query: 177 DSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTF 236
           D  V+ +    +P               L  G      L     W D GT D  ++    
Sbjct: 178 DPGVLSWIPPERP----VSVERETFPALLRDGVRVYGCLCT-GYWKDIGTGDRYLQLHRD 232

Query: 237 VQTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY---GQYLLELLRARPRQ 292
           +          I     +     W  D+      + +    Y   G  +    +  PR 
Sbjct: 233 ILEGR----CPIPVSGPVRGPAHWQADDADVSPDARIMPPVYIGSGAVIEAGAQVGPRA 287


>UniRef50_B0BZ78 Nucleotidyl transferase protein n=5 Tax=Cyanobacteria
           RepID=B0BZ78_ACAM1
          Length = 323

 Score =  258 bits (659), Expect = 2e-67,   Method: Composition-based stats.
 Identities = 63/305 (20%), Positives = 115/305 (37%), Gaps = 25/305 (8%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +I+AGG GTRL P+T    K +LP++++P + + +      G+ +IL+    +    
Sbjct: 1   MQAVIIAGGKGTRLSPLTLRSPKPMLPLFERPFLSWMVERCKAVGLTDILMNIRYQA-TQ 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            Q   GDG +FG+++ Y  +      A A  + E F  GEP  +V   +I         +
Sbjct: 60  IQEYFGDGQKFGVKIRYVIEKEALDTAGAMKLAEPFYTGEP-LVVFNADILTNLNLQALM 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDD--------NFRAISLEEKPKQPKS-----N 167
           +        AT+   +V DP  FG+VE  D             S  EKP   ++     +
Sbjct: 119 QAHEQTQAQATIALARVADPTAFGLVELTDITASEHSSTGTIQSFREKPTPEEAATLGID 178

Query: 168 WAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTH 227
               G Y  + ++       +P         ++    L         +     W+D GT 
Sbjct: 179 TVNAGTYVLNPEIFAQYPADQPL----SFERTVFPNLLSNQQKISGFV-WEGYWMDLGTP 233

Query: 228 DSLIEASTFVQTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLR 287
                A   +     +  F +    E      W+ +  +    + ++   +   L E  +
Sbjct: 234 AKFYGAHLDILQG--KMPFPLPEAMEERQPQVWVANNAIIDPQAKISGPCF---LGENAK 288

Query: 288 ARPRQ 292
             P+ 
Sbjct: 289 LGPQA 293


>UniRef50_A9A224 Nucleotidyl transferase n=3 Tax=Thaumarchaeota RepID=A9A224_NITMS
          Length = 238

 Score =  258 bits (659), Expect = 2e-67,   Method: Composition-based stats.
 Identities = 51/238 (21%), Positives = 104/238 (43%), Gaps = 11/238 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +K +ILAGG GTRL P+T    K +LP+  KP++ + +      G++ I++  +   +  
Sbjct: 4   VKAVILAGGLGTRLRPLTLKTPKPMLPLGKKPILEHLIDWNKRNGVKSIVLCVSYRKEK- 62

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            Q    DG +FG+ +EYA    P   A      E F+N   + + +  +  F       +
Sbjct: 63  IQDYFKDGKKFGVNIEYAVSKKPLATAGQLKTAEDFIND--TFVCVYGDSIFDFSLKNMI 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           +   ++    T+  Y+     ++GV+      +  + EEKP+   +     G Y  +  V
Sbjct: 121 KQHKSKKAFTTMSLYEYKTNLQYGVINTTKTGKVTNWEEKPEIKAN--INMGCYVMEPNV 178

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           ++Y  + KP       +  + +  ++   +    + +   ++D G  +S  +A+    
Sbjct: 179 LKYIPKNKP-----YGMDDVIKKAMKNKKMISGFITKKG-FMDIGNKESYKQANEEFA 230


>UniRef50_A4YHT6 Glucose-1-phosphate thymidyltransferase n=1 Tax=Metallosphaera
           sedula DSM 5348 RepID=A4YHT6_METS5
          Length = 349

 Score =  256 bits (656), Expect = 5e-67,   Method: Composition-based stats.
 Identities = 92/279 (32%), Positives = 141/279 (50%), Gaps = 11/279 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+ILAGG GTRL P+T   +K  +PI +KPM+ Y +  L+ AGIR+I++I  P  +G 
Sbjct: 1   MKGLILAGGHGTRLRPLTHTGNKHAIPIANKPMVLYAVENLVNAGIRDIVVILGPLKEGI 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            + + G+   +     Y EQ  P GLA A +  E +L  +   ++   +     G S  +
Sbjct: 61  KEAIDGN---YPANFTYVEQ-EPLGLAHAVMKAEKYL--DEPFVMHLGDNLLQNGISQFV 114

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                    A +    V DP ++GVV   +N R   L EKP+ P SN A+ G+Y +   V
Sbjct: 115 NKFHETKADAVIGVTPVKDPRQYGVVVI-ENGRVKRLMEKPRDPPSNLALVGVYVFTPVV 173

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ-T 239
            +Y K++KPS RGE EIT + Q+ +E G   VE++     W DTG  + L+EA+  V  +
Sbjct: 174 HDYTKRLKPSWRGEYEITDVLQLMVEDGRR-VEVVQVEGWWKDTGKPEDLLEANQLVLDS 232

Query: 240 VEKRQGFKIACLE--EIAWRNGWLDDEGVKRAASSLAKT 276
           +        A +E          L +  + R  + + K 
Sbjct: 233 LHGSFRHDHAKIEGRVQVGEGTVLRENVIIRGPAIIGKN 271


>UniRef50_B0R8I5 Sugar nucleotidyltransferase n=2 Tax=Halobacterium salinarum
           RepID=B0R8I5_HALS3
          Length = 395

 Score =  256 bits (655), Expect = 7e-67,   Method: Composition-based stats.
 Identities = 63/306 (20%), Positives = 117/306 (38%), Gaps = 23/306 (7%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ ++LA G G RL P+T    K ++P+ ++P++ + +  L+ AG+  ++++     +  
Sbjct: 1   MQAVVLAAGKGERLWPLTENRPKPMVPVANQPILEHIVDALVSAGVTRVMLVVGSN-RER 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGF-SPK 119
            QR   DGS +GI++ Y  Q    G   A    E+ +    S + L  +           
Sbjct: 60  VQRHFEDGSRWGIEISYVVQDRQLGTGHALAQAESVVG--ESFVALNGDRVIDASLVEDV 117

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEK--PKQPKSNWAVTGLYFYD 177
                   + A +   QV  P  +GVV+ D       ++E+  P+   S +   G+Y + 
Sbjct: 118 WECHRESGDSA-MGVTQVETPSAYGVVDLDG-GTVTDIDEQPVPELVASEYINAGVYAFG 175

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
             V    ++      GEL +T      L    L    +     WLD      L+ A++ +
Sbjct: 176 PSVFAAIRRTDSY--GELALTDALDEQLADHEL--RAVRYDGRWLDVSEPWDLVAANSAL 231

Query: 238 ---------QTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKT--GYGQYLLELL 286
                        K +G      ++     G +  EGV     ++ +     G  +    
Sbjct: 232 ITDRRFDPPVERRKPRGSVPGDDQQAPVGGGTVCGEGVIVHPQAVVRNGVALGDNVTVGA 291

Query: 287 RARPRQ 292
            A   Q
Sbjct: 292 NAVIEQ 297


>UniRef50_P08075 Glucose-1-phosphate thymidylyltransferase n=49 Tax=Bacteria
           RepID=STRD_STRGR
          Length = 355

 Score =  256 bits (655), Expect = 7e-67,   Method: Composition-based stats.
 Identities = 91/293 (31%), Positives = 138/293 (47%), Gaps = 8/293 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++LAGG+GTRL PIT   +KQL+P+ +KP+++Y L  +  AGI ++ I+        
Sbjct: 1   MKALVLAGGTGTRLRPITHTSAKQLVPVANKPVLFYGLEAIRAAGIIDVGIVVGDTADEI 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
               +GDGS FG+++ Y  Q  P GLA   +I   FL  +   + LGDN   G      +
Sbjct: 61  V-AAVGDGSRFGLKVSYIPQSKPLGLAHCVLISRDFLGEDDFIMYLGDNFVVGV-VEDSV 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           R   A    A +   +V +P  FGV E  D+ + + LEEKP  PKS+ A+ G+Y +   +
Sbjct: 119 REFRAARPDAHLMLTRVPEPRSFGVAELSDSGQVLGLEEKPAHPKSDLALVGVYLFSPAI 178

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            E    + PS RGELEIT   Q  ++AG      +     W DTG    ++E +  V   
Sbjct: 179 HEAVAAITPSWRGELEITDAVQWLIDAGRDVRSTVI-SGYWKDTGNVTDMLEVNRLVLET 237

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRARPRQY 293
                 +  C   +  R+  +    V+  A        G  ++         Y
Sbjct: 238 -----TEPRCDGLVDERSDLIGRVLVEEGAEVRNSRVMGPTVIGAGTRVTNSY 285


>UniRef50_Q97EQ2 Nucleoside-diphosphate-sugar pyrophosphorylase n=1 Tax=Clostridium
           acetobutylicum RepID=Q97EQ2_CLOAB
          Length = 234

 Score =  256 bits (655), Expect = 8e-67,   Method: Composition-based stats.
 Identities = 58/232 (25%), Positives = 100/232 (43%), Gaps = 9/232 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +IL GG GTRL  + +   K +  + +KP + Y +  L   GI +I++ T      +
Sbjct: 1   MQALILVGGLGTRLRSVVKDRPKPMALVENKPFLEYLIRKLKSNGISDIILATGY-MSEF 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +    DG EFG+ + Y+++ +  G A A    E +L  E    VL  + +F   F    
Sbjct: 60  IENYFKDGREFGVNIVYSKETTQLGTAGAIKNAEEYLKEE--FFVLNGDTYFDVDFESAY 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           +         T+   +  D  R+G VE  D+ R +S  EK    KSN+   G+Y    ++
Sbjct: 118 KFHKNNKSYFTMILRETSDASRYGAVECSDDNRVVSFIEKGGISKSNYINGGIYIVKKEI 177

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIE 232
            +  ++    E+     T I    L  G   +        ++D G  +  I+
Sbjct: 178 FKEIER----EKKVSLETEIIPKVL--GEEVIYGYKCNNYFIDIGVPEDYIK 223


>UniRef50_UPI000197A125 nucleotidyl transferase n=1 Tax=Helicobacter cinaedi CCUG 18818
           RepID=UPI000197A125
          Length = 348

 Score =  255 bits (653), Expect = 1e-66,   Method: Composition-based stats.
 Identities = 52/234 (22%), Positives = 98/234 (41%), Gaps = 11/234 (4%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQR 63
           +I+AGG G RL P+T  + K +L +  KP++   L      G   I++    +     + 
Sbjct: 124 VIMAGGLGKRLRPLTDSIPKPMLKVGSKPILQIILERFKAQGFSNIILCVNYKSH-IIED 182

Query: 64  LLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHV 123
             GDGS+FG+ + Y ++    G A A  + +    GE    V+  +I     F   L   
Sbjct: 183 FFGDGSKFGLSIRYVKEEKALGTAGALSLIDNI--GEKPFFVMNGDILSDISFQAMLEFH 240

Query: 124 AARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEY 183
             R   AT+   +      +GVVE +++ + +++ EKP Q  S     G+Y  + +++  
Sbjct: 241 NERGSHATMGVREYSYQVPYGVVECEES-KILNIIEKPTQ--SFLVSAGIYVLEPQILPL 297

Query: 184 AKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
             +         ++ S+  +     +           W+D G H+    A++  
Sbjct: 298 IPKDCF-----FDMPSLFNLIFSQAHYNSHSYLITDYWIDIGRHEEYERANSEY 346


>UniRef50_Q1J1J1 Glucose-1-phosphate thymidyltransferase n=10 Tax=Deinococci
           RepID=Q1J1J1_DEIGD
          Length = 355

 Score =  255 bits (652), Expect = 2e-66,   Method: Composition-based stats.
 Identities = 79/279 (28%), Positives = 121/279 (43%), Gaps = 9/279 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK II A G GTRL P+T    K +LP+   P+I + L  L+ AGI E+ II +   +  
Sbjct: 4   MKAIIPAAGLGTRLRPLTYTRPKPVLPVAGAPIIVHALRTLLAAGINEVGIIVSDATRAE 63

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
             + L    E  +Q+    Q    GL  A +    ++  +  C+ L  +  F  G +P +
Sbjct: 64  IAQTLEQVPE--VQVTLINQHEQLGLGHAVLTARNWVGQQNFCVYL-GDNLFEHGVAPFI 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                    A +   +V DP  FGV E +   R   L EKPK P SN AV GLY +  +V
Sbjct: 121 ERFQREQAAAVIALVEVPDPTAFGVAELEGE-RITRLVEKPKVPPSNLAVAGLYCFTPEV 179

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            +    + PS RGE EIT   Q  ++ G   +    +   W DTG    L++A+  +   
Sbjct: 180 FDVLDGMPPSARGEYEITDAIQGLVDRGQTVLGQCVQ-GWWKDTGRPADLLDANRLLL-- 236

Query: 241 EKRQGFKI-ACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
            ++ G  +   +E        +     +   S +     
Sbjct: 237 -EQIGADVQGEVEGSRLTGRVIIPASARVTRSKIVGPVL 274


>UniRef50_A8GZ91 Nucleotidyl transferase n=5 Tax=Gammaproteobacteria
           RepID=A8GZ91_SHEPA
          Length = 397

 Score =  254 bits (649), Expect = 3e-66,   Method: Composition-based stats.
 Identities = 59/292 (20%), Positives = 113/292 (38%), Gaps = 23/292 (7%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+ILA G GTR+ PI+  + K ++PI  KP++   + +    GI +I+I T+      
Sbjct: 1   MKGMILAAGKGTRIKPISYAIPKPMVPILGKPVMESMIQLFAKHGIDKIVINTSH-LAEI 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPS---------PDGLAQAFIIGETFLN-GEPSCLVLGDNI 110
            +   GDG  F +QL Y+ +             G A      + F    + + +V+  + 
Sbjct: 60  IESYFGDGHHFNVQLSYSYEAKEVNGEYISQALGSAGGMRKIQDFSGFFDETFVVVCGDA 119

Query: 111 FFGQGFSPKLRHVAARTEGATVFGYQV--MDPERFGVVEFDDNFRAISLEEKPK--QPKS 166
           +        + H  +    AT+   +V   +  ++GVV  D + +  S +EKP   +  S
Sbjct: 120 WIDLDLKQAIEHHKSHGGLATIITREVASSEVSKYGVVVTDKHNQVTSFQEKPAEDEALS 179

Query: 167 NWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGT 226
           N   TG+Y ++  + ++  +    + G    + +  + +E        +   F WLD G 
Sbjct: 180 NRINTGIYIFEPAIFDFIPKDVEFDIG----SDLFPLLVERQANL-YAINMDFQWLDVGK 234

Query: 227 HDSLIEASTFVQTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
              + E ++ +     +                W+                 
Sbjct: 235 VKDVWEVTSDILNGNVK---GYPIPGTQVSPGVWVGINTRVDTTKCKITPPV 283


>UniRef50_B6BGD8 Nucleotidyl transferase n=1 Tax=Campylobacterales bacterium GD 1
           RepID=B6BGD8_9PROT
          Length = 353

 Score =  253 bits (647), Expect = 6e-66,   Method: Composition-based stats.
 Identities = 46/243 (18%), Positives = 101/243 (41%), Gaps = 12/243 (4%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K +++ GG GTRL P+T  + K LL + +KP++   +      G ++ ++    + +   
Sbjct: 121 KVVLMVGGLGTRLRPLTDDMPKPLLKVGNKPILETIIDNFSKYGFKDFILSVNYKSE-MI 179

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLR 121
           ++  G+GS FG+ +EY ++    G A A  +    L  +    V+  ++     +   L 
Sbjct: 180 KKHFGNGSRFGVNIEYVQEDKRMGTAGALSLMREKLKDD--FFVMNGDLLTNVNYEHLLN 237

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVV 181
           +       AT+   +      +GVV   ++    S+ EKP      +   G+Y      +
Sbjct: 238 YHLNDNAVATMCVKEYDFQIPYGVVNI-EHNHITSISEKPIH--KFFVNAGIYMLSPSTL 294

Query: 182 EYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVE 241
           E+    +       ++ ++    ++    ++    R   WLD G  +   +A+     + 
Sbjct: 295 EFIPNNEF-----FDMPTLFDNLIQHKQKSISFPIRE-YWLDIGEIEEYKKANIEYLDIF 348

Query: 242 KRQ 244
           + +
Sbjct: 349 EGK 351


>UniRef50_Q2WB86 Nucleoside-diphosphate-sugar pyrophosphorylase n=7 Tax=Bacteria
           RepID=Q2WB86_MAGSA
          Length = 349

 Score =  253 bits (646), Expect = 7e-66,   Method: Composition-based stats.
 Identities = 60/238 (25%), Positives = 94/238 (39%), Gaps = 12/238 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +++AGG G RL P+T+ V K LLP+  +P++   L   + AG R   I      +   +
Sbjct: 122 VVLMAGGEGRRLRPLTQDVPKPLLPVGPRPILETILKNFIEAGFRNFFISVNYRAE-QVE 180

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
              GDGS  G+ + Y  +    G A A  +           +V+  +I     F   L  
Sbjct: 181 SHFGDGSALGVSIRYLREDRQLGTAGALGLLPG--TPSEPLIVMNGDILTTVDFKQLLAF 238

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
                  AT+   +      +GVVE +   R   +EEKP     N+   G+Y  + +V+ 
Sbjct: 239 HQEHRAAATMAVREYHFEVPYGVVEVEGT-RLKGIEEKP--VVRNFVNAGIYVLNPEVLN 295

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
             K  +P       +  I Q  ++ G        R   WLD G  D    A+     V
Sbjct: 296 LVKPGQPHN-----MPQIYQTLMDGGQDCAVFPIRE-YWLDIGRLDDFDRANLDFHEV 347


>UniRef50_C7LY80 Nucleotidyl transferase n=1 Tax=Acidimicrobium ferrooxidans DSM
           10331 RepID=C7LY80_ACIFD
          Length = 346

 Score =  253 bits (646), Expect = 8e-66,   Method: Composition-based stats.
 Identities = 67/280 (23%), Positives = 111/280 (39%), Gaps = 14/280 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ IIL GG GTRL P+T    KQ+L +   PM+   +  L   G+ E+++    +   +
Sbjct: 1   MQAIILVGGEGTRLRPLTLHQPKQMLRLLGFPMLERVVERLAAIGVDEVVLSLGYQPDAF 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
             R   D     +++ YA +P P   A A        N   + LV+  ++      +  +
Sbjct: 61  IARY-PDHRIGTVKVRYAVEPEPLDTAGAIRFAVDKGNVHGTFLVVNGDVLTDLDVAQLV 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDS 178
                R   AT+   +V DP RFGVV  DD  RA+   EKP   Q  S+    G+Y  + 
Sbjct: 120 DFHLDRGALATIGLVEVDDPSRFGVVVTDDRGRAVRFVEKPPRDQAPSHAINAGVYVMEP 179

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
             +E     +          S+       G L    L +   W+D GT  S + A+  + 
Sbjct: 180 AAIERIAVGER----VSVERSLFPQLASEGTLWG--LAQRCYWVDAGTPASYLRAALDIA 233

Query: 239 TVEKRQGFKIACLEEIAWRNG-----WLDDEGVKRAASSL 273
           T  +    +      +  R       +L +     + + +
Sbjct: 234 TGRRAARVREGVRFPVESRPPGGETCYLGEGSQVASDAVV 273


>UniRef50_A0B7L5 Nucleotidyl transferase n=1 Tax=Methanosaeta thermophila PT
           RepID=A0B7L5_METTP
          Length = 403

 Score =  252 bits (645), Expect = 9e-66,   Method: Composition-based stats.
 Identities = 58/279 (20%), Positives = 105/279 (37%), Gaps = 14/279 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ IILA G G+R+ P+T    K +LP+   P++   +     AGI   + +     +  
Sbjct: 4   MQAIILAAGEGSRMRPLTASRPKVMLPVGGAPLLEELVLRCREAGINRFVFVVGYR-RDV 62

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQG-FSPK 119
                 DGS+F + + YA Q    G   A +        +    V+  ++          
Sbjct: 63  VTSYFKDGSDFDVDISYAVQEKQLGTGHALMTARDL--SDDRFFVINGDVLPDVQALRRM 120

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSK 179
           +       E  +V  ++V++  R+GV     +     + EK   P S+ A  G+Y  D +
Sbjct: 121 I-----SMEDLSVATHRVVEASRYGVFLL-RDGLVEGVVEKSPSPPSDMANAGIYLLDRE 174

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           + E  ++V  S RGE E+T        AG     +      W++ G    ++ AS  V +
Sbjct: 175 IFELMEEVPVSIRGEYELTDGINALASAGRKIWAIELSE--WVEVGVPWDILTASNAVLS 232

Query: 240 VEKRQGFKIACLEEIAWRNGW-LDDEGVKRAASSLAKTG 277
             K              +    +    + R  + +    
Sbjct: 233 -RKVPVMDGDVESGATLKGNVSIGSGTLVRNGAYIEGPV 270


>UniRef50_Q23RS7 Nucleotidyl transferase family protein n=3 Tax=Eukaryota
           RepID=Q23RS7_TETTH
          Length = 706

 Score =  252 bits (645), Expect = 9e-66,   Method: Composition-based stats.
 Identities = 56/304 (18%), Positives = 114/304 (37%), Gaps = 27/304 (8%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +IL GG GTRL P+T    K ++   ++P++ + +  L+  G+ +I++    + K  
Sbjct: 1   MKALILVGGFGTRLRPLTFSCPKSIVEFANQPLVTHQIKALVDVGVTDIILAIGFQPKAM 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFL---NGEPSCLVLGDNIFFGQGFS 117
            +++     E+ +++  +++  P G      + +  L   N E    VL  ++     F 
Sbjct: 61  IEKIKQFEEEYKVRIICSQEVEPLGTGGPLRLAKEHLVKDNPEGLFFVLNSDVICDFPFK 120

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYD 177
             L       +  T+   +V DP ++GVV  D N R     EKPKQ  S+    G+Y ++
Sbjct: 121 EMLAFHKNHQKEGTILLTKVQDPTKYGVVVSDSNGRIERFIEKPKQFISDRINAGIYLFN 180

Query: 178 SKVVEYAK----------------QVKPSERGELEITS-INQMYLE-------AGNLTVE 213
           + V++                    +      +  +   +    LE       A    + 
Sbjct: 181 TSVIDRIPVILFLFLPNFLHLAIIHLLIFIFKKYFVNQQLEPHMLELNTFPTMAKEAQLY 240

Query: 214 LLGRGFAWLDTGTHDSLIEASTFVQTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSL 273
            +     W+D G     +  +T +    + +        +    N  +D        + +
Sbjct: 241 SMDLPGFWMDVGQPKDFVIGTTLILESIRTKNPSALSTGQNIIGNVLIDPTAKISPTAVI 300

Query: 274 AKTG 277
               
Sbjct: 301 GPNV 304


>UniRef50_Q1Q6W7 Putative uncharacterized protein n=2 Tax=Bacteria
           RepID=Q1Q6W7_9BACT
          Length = 632

 Score =  252 bits (645), Expect = 1e-65,   Method: Composition-based stats.
 Identities = 58/305 (19%), Positives = 122/305 (40%), Gaps = 23/305 (7%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +ILAGG GTR+  +++ + K ++ I +KP++ Y + +     + +I+++T  +    
Sbjct: 1   MKVVILAGGKGTRMGSLSQNIPKPMINIANKPILQYQIEIAKRFNLTDIILLTGYK-GEV 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   G+G  +G+ +    +  P G A A    E +L+ +   LV   ++         +
Sbjct: 60  VEDYFGNGENWGVNISCYRETIPLGTAGAVKEVEDYLHDD--FLVFYGDVIMDIDLKSVI 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP---KQPKSNWAVTGLYFYD 177
           R+   R   AT+  +    P    ++E ++  + I+   KP        N     LY   
Sbjct: 118 RYHMKRKPIATLVVHPNDHPYDSDLIEVNNEGKVITFHSKPHKQDIFIRNLVNAALYILS 177

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
            +++ +  +   S+ G      I    +  G +        +   D GT + L E    +
Sbjct: 178 PRIMNFLPKGTYSDFG----KDIFPKLVNDGEIIYAYNTPEYI-KDIGTLERLEEVERDI 232

Query: 238 QTVE--------KRQGFKIACLE----EIAWRNGWLDDEGVKRAASSLAKTGYGQYLLEL 285
            + +        KR+   +        EI       + E +    +++ K    +YL  +
Sbjct: 233 VSGKLYRLNKKNKRKAIFLDRDGVLNYEIDLLRTPEELELLPDVPNAIKKINTSEYLSVV 292

Query: 286 LRARP 290
           +  +P
Sbjct: 293 VTNQP 297


>UniRef50_C8SCM3 Nucleotidyl transferase n=1 Tax=Ferroglobus placidus DSM 10642
           RepID=C8SCM3_FERPL
          Length = 390

 Score =  252 bits (645), Expect = 1e-65,   Method: Composition-based stats.
 Identities = 64/279 (22%), Positives = 123/279 (44%), Gaps = 20/279 (7%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +ILA G G RL P T    K ++ + +KP++ Y +  L  AGIREI+++   + +  
Sbjct: 1   MKAVILAAGEGQRLRPFTANKPKVMIKVGNKPILEYVVDALKEAGIREIVMVVGYKKERV 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFG-QGFSPK 119
                G+G +FG+++EY  Q    G A A    +  + G+   LVL  +     +     
Sbjct: 61  I-DYFGNGEKFGVKIEYVTQKQQLGTAHALKQAKDLVEGK--FLVLPGDNIIDSETLKDV 117

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSK 179
           L +     +  +V    V +P ++GV+E  +N +   + EKP++  S  A TG+Y  D +
Sbjct: 118 LSY-----DTFSVVYKVVEEPTKYGVLEV-ENGKVKRIIEKPEEEVSYLASTGIYLLDDR 171

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           + E+          E ++T++  + +E+G     +      WLD      +++ +  +  
Sbjct: 172 IFEFI-------GDERDLTNVVNVMIESGIDFFTV-ESKGLWLDIVYPWDILKVN-DLAL 222

Query: 240 VEKRQGFKIACLEEIAWRN-GWLDDEGVKRAASSLAKTG 277
             K +         +       + +  + R+ S +    
Sbjct: 223 KHKGKSIAGKVESGVTIVGDVVIGEGSIIRSGSFIKGPV 261


>UniRef50_A6UUQ4 Glucosamine-1-phosphate N-acetyltransferase n=6 Tax=Methanococcales
           RepID=GLMU_META3
          Length = 411

 Score =  252 bits (644), Expect = 1e-65,   Method: Composition-based stats.
 Identities = 62/278 (22%), Positives = 125/278 (44%), Gaps = 16/278 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M  +IL  G GTRL P+T  + K +LP+   P++   ++ +    +  I +I   E +  
Sbjct: 1   MDAVILCAGKGTRLMPLTENIPKPMLPVGGAPILERIINKIDKL-VENIYLIVKYEKE-I 58

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                 +      ++++ EQ   DG   A ++ +  ++G+   LV+  +I F    +  +
Sbjct: 59  IINHFKNND----KIKFIEQTDIDGTGYAVLMAKNHISGD--FLVINGDIIFDDDLTNIV 112

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                      +   +V +P  FGV+  D+    I L+EKPK PKSN    G+Y +++K+
Sbjct: 113 NDDVKN----IITLNEVDNPSNFGVIVVDNQNNIIELQEKPKNPKSNLINAGIYKFENKI 168

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            +  + ++PSERGE+E+T   +  ++  N+    +     W D G    L++A+T +   
Sbjct: 169 FDILETLRPSERGEVELTDAIKELIKENNIKG--IKLNGYWNDIGKPWDLLDANTHILKN 226

Query: 241 EKRQGFKIACLEEIAWRN-GWLDDEGVKRAASSLAKTG 277
             +   K    + +       +++    +  + +    
Sbjct: 227 I-KTDIKGKIGKNVVIEGAVIIEEGTEIKPNTVIEGPA 263


>UniRef50_D2RY68 Nucleotidyl transferase n=2 Tax=Halobacteriaceae RepID=D2RY68_9EURY
          Length = 248

 Score =  251 bits (643), Expect = 2e-65,   Method: Composition-based stats.
 Identities = 67/253 (26%), Positives = 116/253 (45%), Gaps = 7/253 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ ++LA G GTRL P+T    K L+ + DKP+I      L+  G+ +I+++   + +  
Sbjct: 1   MQAVVLAAGKGTRLRPLTDDKPKVLVEVNDKPLIEDVFDNLLEIGVNDIVVVVGYQKEQI 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +R  GD  E G+ + YA Q    GLA A +  E  +  E   L+LGDN+F        +
Sbjct: 61  IERY-GDEYE-GVPITYAHQRKQLGLAHAILQAEPHI-DEDFVLMLGDNVF-RGNLGDVV 116

Query: 121 RHVAARTEGATVFGYQV--MDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDS 178
                    A     +V   +  R+GV++ ++    + + EKP  P SN  +TG Y +  
Sbjct: 117 NRQQEDRADAAFLVEEVPYEEASRYGVLDTNEYGEIVEVVEKPDDPPSNLVMTGFYTFTP 176

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
            +      V+PS+RGE E+     + +++G  T++ +      +D G  +    A   +Q
Sbjct: 177 AIFHACHLVQPSDRGEYELPDAIDLLIQSGR-TIDAIRMDGWRIDVGYPEDREAAEERLQ 235

Query: 239 TVEKRQGFKIACL 251
              K     +   
Sbjct: 236 DDGKAVEAAVTAE 248


>UniRef50_Q2LPS3 Glucose-1-phosphate adenylyltransferase n=3 Tax=cellular organisms
           RepID=Q2LPS3_SYNAS
          Length = 240

 Score =  251 bits (643), Expect = 2e-65,   Method: Composition-based stats.
 Identities = 56/244 (22%), Positives = 104/244 (42%), Gaps = 12/244 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++LAGG G RL P T+ + K L+PI D P++   L  + +AGI  +++         
Sbjct: 1   MKAVVLAGGKGARLAPYTKILPKPLMPIGDMPILEVLLRQMKVAGIDHVILTVGH-LSEL 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +    DGS+FG+ + Y+ +  P G A    + +     + + LV   ++         +
Sbjct: 60  LRAFFQDGSQFGVDISYSYEKCPLGTAGPISLIDGL---DETFLVTNGDVLTTLSLRELI 116

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                +   AT+  +Q       GV++++ N+      EKP    +     G+Y ++ KV
Sbjct: 117 GFHREQKAAATIAVHQRQTKIDLGVIQWNGNYEVKGYIEKPVYDYT--VSMGVYVFEPKV 174

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           + Y    +      L+   + +  + AG   V        W D G  D    AS   +++
Sbjct: 175 LSYIPHGEY-----LDFPDLVKKLIAAGEKVVGYRFH-GYWEDLGRPDDYERASRDFESM 228

Query: 241 EKRQ 244
            ++ 
Sbjct: 229 REQF 232


>UniRef50_B5GDG2 Nucleotide phosphorylase n=1 Tax=Streptomyces sp. SPB74
           RepID=B5GDG2_9ACTO
          Length = 360

 Score =  251 bits (642), Expect = 2e-65,   Method: Composition-based stats.
 Identities = 61/282 (21%), Positives = 111/282 (39%), Gaps = 12/282 (4%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            I+L GG GTRL P+T    K ++P    P + + L+    AG+  I++ T+      F+
Sbjct: 25  AILLVGGKGTRLRPLTVNTPKPMVPAAGVPFLAHQLARARAAGVEHIVLATSY-LAEVFE 83

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFL--NGEPSCLVLGDNIFFGQGFSPKL 120
              GDGS FG++++Y  +  P G   A     + L    E   LV   +I  G   +  +
Sbjct: 84  PYFGDGSAFGLRVDYVTEREPLGTGGALRNVASHLESGPEDPVLVFNGDILTGLDINALV 143

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPK---SNWAVTGLYFYD 177
                     ++   +V DP  FG+V  D + R ++  EKP+ P+   ++    G Y + 
Sbjct: 144 DTHVTAGADVSLHLSRVDDPRAFGLVPTDASGRVLAFLEKPQTPEEIVTDQINAGAYVFR 203

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
            +V++     +P               L +G     ++     WLD GT  + +  S  +
Sbjct: 204 RRVIDAIPGGRP----VSVERETFPGLLASGAHLQGMV-DSTYWLDLGTPQAFVRGSADL 258

Query: 238 -QTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
                        C E +      + ++      + + +   
Sbjct: 259 VLGHAPSPAVPGRCGEHLVLPTAEVAEDAKLTGGTVVGEGAV 300


>UniRef50_UPI0001C16C8D Mannose-1-phosphate guanyltransferase CBS pair associated n=1
           Tax=Raphidiopsis brookii D9 RepID=UPI0001C16C8D
          Length = 349

 Score =  251 bits (641), Expect = 3e-65,   Method: Composition-based stats.
 Identities = 53/237 (22%), Positives = 99/237 (41%), Gaps = 12/237 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +I+AGG GTRL+P+T+   K LL +  KP++   +      G ++I +    + +   +
Sbjct: 124 VVIMAGGLGTRLYPLTKDRPKPLLTVGGKPILEIIIENFAEQGFKQIFLSVNYKAE-MIE 182

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
               +G ++G+++ Y  +    G A A  +           +V+  +I     F   L+ 
Sbjct: 183 DYFKNGDQWGVEISYLREKERLGTAGALSLLPK--KPNLPIIVMNGDILTRTRFDNLLQF 240

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
              +   AT+   +      +GVV  D   +  S+EEKP Q    +  +G+Y     V++
Sbjct: 241 HELQGVLATMAVREYDLQVPYGVVRVDGT-KIKSIEEKPVQHF--FVNSGIYALSPGVLD 297

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           Y            ++ S+ Q  +     T     R   WLD G    L  A+  +++
Sbjct: 298 YVPSGTF-----FDMPSLFQQLVVDTRTTAAYPLRE-YWLDIGRMSDLERANEELRS 348


>UniRef50_B1BCE9 Nucleotidyl transferase n=2 Tax=Clostridium RepID=B1BCE9_CLOBO
          Length = 345

 Score =  250 bits (639), Expect = 4e-65,   Method: Composition-based stats.
 Identities = 59/233 (25%), Positives = 93/233 (39%), Gaps = 12/233 (5%)

Query: 5   ILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQRL 64
           ILAGG GTRL P+T  + K +L I DKPM+   +      G +  +I    +     +  
Sbjct: 121 ILAGGLGTRLRPLTEKLPKPMLKIGDKPMLERIIKQFRGYGFKNFIISINYK-GEVIEDY 179

Query: 65  LGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHVA 124
             DGSEF + +EY  +    G A +  + +  LN +   +V+  +I  G  F   L +  
Sbjct: 180 FKDGSEFDVNIEYVREEKKLGTAGSISLAKNKLNKD--FIVINGDILTGIDFEELLNYHE 237

Query: 125 ARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEYA 184
                 T           +GV+   D     SLEEKP    + +  +G+Y     VV+Y 
Sbjct: 238 ENKYDITAGARNYEMKVPYGVMVMKDE-LIQSLEEKPT--YNFYINSGVYVLSKDVVKYI 294

Query: 185 KQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
              K     E  +T + +  +               W D G  +   +A+  V
Sbjct: 295 PDNK-----EYNMTDLIEDVINNNGRCGAYNITE-YWSDIGHIEDYKKANEDV 341


>UniRef50_B8D5T2 Putative sugar-phosphate nucleotidyl transferase n=2
           Tax=Thermoprotei RepID=B8D5T2_DESK1
          Length = 283

 Score =  249 bits (638), Expect = 6e-65,   Method: Composition-based stats.
 Identities = 60/240 (25%), Positives = 101/240 (42%), Gaps = 11/240 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M  +ILAGG G RL P T  V K ++P+ DKP++ + +  L   G REI+++     +  
Sbjct: 43  MLAVILAGGYGKRLRPYTDDVPKPMIPVGDKPILEWQIEWLKKYGFREIVLLVGYRKEKI 102

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  +G GS  G+++ Y  +  P G   A    E  L+   + LV+  +I         +
Sbjct: 103 IE-YIGSGSRLGVRVTYVVEDEPLGTGGAIKNAEHVLSRNGTFLVINGDIITNLNPLKLV 161

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
             +        +    +  P  +GV+E +D  R     EKP+     W   G+Y  + + 
Sbjct: 162 EKLEGSRYLGVIASIPL--PSPYGVLEIEDEDRVKGFVEKPQLSD-YWINAGVYALNPEA 218

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           + Y  +     +G+LE T         G +   +   G  W    T   L EAS  +  +
Sbjct: 219 LRYFPE-----KGDLEKT-AFPAMARDG-VLGTVRYTGVFWKAIDTFKELEEASRAIHEI 271


>UniRef50_C7LVF0 Nucleotidyl transferase n=2 Tax=Proteobacteria RepID=C7LVF0_DESBD
          Length = 355

 Score =  249 bits (638), Expect = 7e-65,   Method: Composition-based stats.
 Identities = 48/235 (20%), Positives = 89/235 (37%), Gaps = 12/235 (5%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQR 63
           +I+AGG GTRL P T    K +LP+  KPM+ + +      G R  ++          + 
Sbjct: 128 VIMAGGMGTRLLPYTEDCPKPMLPVAGKPMLEHIIERAKNEGFRHFVLAVRY-LAHVVED 186

Query: 64  LLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHV 123
             GDG+++ +++ Y  + +P G A A  + +         +V   ++     +   +   
Sbjct: 187 YFGDGAKWDVRISYLHEDTPLGTAGALGLLDP--KPMEPVVVTNGDVLTDVRYGEIVDFH 244

Query: 124 AARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEY 183
                 AT+          FGVV+ +     +  EEKP          G+Y   ++ +  
Sbjct: 245 IYHQAAATMAVRMHEWQHPFGVVQTNGV-SIVGFEEKP--VFRTHVNAGIYVLGAEALRL 301

Query: 184 AKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
               KPS+     +  I ++        +        W D G  D L +    ++
Sbjct: 302 VPSGKPSD-----MPDIFELLRLRDERIIAYPMHE-IWTDVGRPDDLKKVRNEMR 350


>UniRef50_A8G626 Nucleoside-diphosphate-sugar pyrophosphorylase n=1
           Tax=Prochlorococcus marinus str. MIT 9215
           RepID=A8G626_PROM2
          Length = 352

 Score =  249 bits (636), Expect = 1e-64,   Method: Composition-based stats.
 Identities = 63/231 (27%), Positives = 96/231 (41%), Gaps = 12/231 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            II+AGG G+RL P T    K +L I  KP++   +   + +G RE  I      K   +
Sbjct: 127 VIIMAGGLGSRLRPHTDKCPKPMLKINGKPILEIIIKNCIDSGFREFFISVNY-LKNIIK 185

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
              GDGS++GI++ Y E+  P G   + I+    L      LVL  ++      S  L  
Sbjct: 186 DYFGDGSKWGIKISYLEENEPLGTGGSLILLPKDLKN--PFLVLNGDVLTKFNPSKLLEF 243

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
                  AT+   + +    FGVVE D   +   L EKP  PK      G+Y  +  V+ 
Sbjct: 244 HNKNNATATLSVREYILEVPFGVVETDG-LQVTDLLEKPSYPK--LVNAGVYVLNPNVIS 300

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEA 233
             K  +      L++  +     +     +        WLD G  +SL +A
Sbjct: 301 LIKNEEK-----LDMPELLLRVQQRSQKVIAFPIHE-YWLDIGRLESLKKA 345


>UniRef50_A7ZFS2 Nucleotidyl transferase n=3 Tax=Proteobacteria RepID=A7ZFS2_CAMC1
          Length = 348

 Score =  248 bits (635), Expect = 1e-64,   Method: Composition-based stats.
 Identities = 45/239 (18%), Positives = 96/239 (40%), Gaps = 12/239 (5%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           + I++ GG GTRL P+T+ + K +L + +KP++   +      G   I +          
Sbjct: 121 RVILMVGGLGTRLRPLTKDMPKPMLKVGNKPILQTIVEKFAEYGFVNITMCVNFNA-SII 179

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLR 121
           +   GDG EFG+ ++Y  +    G A A  + +          V+  ++     F     
Sbjct: 180 RDYFGDGKEFGVNIDYVLEQKRMGTAGALSLLKE--RPSEPFFVMNGDLLTNVNFEHIFN 237

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVV 181
           +       AT+   +      +GVV+ +DN +  ++ EKP Q    +   G+Y    +++
Sbjct: 238 YHTLHKATATMCVREYDYEVPYGVVKMNDN-KITAIAEKPVQ--KFFVSAGIYMLSPEIL 294

Query: 182 EYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           +   Q +       ++ ++ +  +      +        W+D G  +   +A+     +
Sbjct: 295 DLIPQDEF-----YDMPTLFEKAIAQDKNVISFPIHE-YWIDIGRLEEYQKANEEYAKI 347


>UniRef50_Q18G10 Glucose-1-phosphate thymidylyltransferase n=5 Tax=Halobacteriaceae
           RepID=Q18G10_HALWD
          Length = 403

 Score =  248 bits (635), Expect = 1e-64,   Method: Composition-based stats.
 Identities = 65/303 (21%), Positives = 113/303 (37%), Gaps = 27/303 (8%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +ILA G GTR+ P+T   +K +LP+  +P+  +     + AG   ++ +   E +  
Sbjct: 1   MQTVILAAGKGTRMRPLTESTAKPMLPVVGEPIAAHTAQAAINAGASRLIFVIGYEAES- 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQ-GFSPK 119
            +   G+  +    + YA Q    G A A    +  L  +P  +VL  +  +        
Sbjct: 60  VKEYFGESYQ-DTPVAYATQTEQRGTADAVRAAKAELTEDP-FVVLNGDNLYDVSSLESL 117

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNF--------RAISLEEKPKQPKSNWAVT 171
                      ++   +V +P  +GV+E  ++         R   + EKP  P SN    
Sbjct: 118 YV------SAPSIGTVRVENPSAYGVLEITEDNESESDMSKRVSGVVEKPANPPSNRINA 171

Query: 172 GLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLI 231
           G Y +  +       V PSER E E+T   Q   E+             WLD G     +
Sbjct: 172 GAYAF-PEAARGWLDVDPSERDEYELTDTLQQTCES---VSVTPVDIDRWLDVGRPWEYL 227

Query: 232 EASTFVQTVEKRQGFKIACLEEIAWRNGWLDD-EGVKRAASSLAKTGYGQYLLELLRARP 290
           EA+ +  + E R  F+     +   R   + + +        +       Y+       P
Sbjct: 228 EANEWKLS-ECRPRFEGDVSPDADLRGSVVVESDATIEPGVVIDGPV---YIASGATIGP 283

Query: 291 RQY 293
             Y
Sbjct: 284 NAY 286


>UniRef50_Q6L165 Mannose-1-phosphate guanyltransferase n=3 Tax=Thermoplasmatales
           RepID=Q6L165_PICTO
          Length = 361

 Score =  248 bits (634), Expect = 2e-64,   Method: Composition-based stats.
 Identities = 63/281 (22%), Positives = 118/281 (41%), Gaps = 18/281 (6%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K +++AGG GTRL PIT  + K L+PI  KP + Y +     AGI++ ++ T  + +   
Sbjct: 4   KAVVMAGGKGTRLRPITYSIPKPLVPIAGKPCVSYLMDSFYDAGIKDAIVTTGYKFESLI 63

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLR 121
             ++ +  +    + ++ +  P G A +  +   F+  + + +V   +I +       + 
Sbjct: 64  NGII-EAKKPDQNVLFSVEREPAGTAGSVKLISNFI--DDTIVVGSGDILYDFDIKSIID 120

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDSK 179
               +    T+   +V DP +FG+V+  D+       EKP   +  SN    G+Y  + +
Sbjct: 121 FHKKKNASVTIVLTRVDDPSQFGIVDLKDD-VITRFLEKPAAGEAFSNIVNAGIYVIEPE 179

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           V++Y  ++            +    +  G      LG    WLDTG  + LI+ +  +  
Sbjct: 180 VLKYIDKIPF-----DFAKELFPRLMRHGTPIYGYLG-NGTWLDTGRPNDLIKGNQIMVN 233

Query: 240 VEKRQGFKIACLEEIAWRNGWLDDEGVKRA--ASSLAKTGY 278
              + GFK    + I  +N       +      SS   T  
Sbjct: 234 ---KYGFKYDS-KNITGKNIIKTTSDLSDDIIDSSYIGTNL 270


>UniRef50_C6D3B0 Nucleotidyl transferase n=1 Tax=Paenibacillus sp. JDR-2
           RepID=C6D3B0_PAESJ
          Length = 330

 Score =  248 bits (633), Expect = 2e-64,   Method: Composition-based stats.
 Identities = 86/290 (29%), Positives = 133/290 (45%), Gaps = 6/290 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+IL  G G+RL+P T+   K L+P+ + P++   +  LM  GI  I I+  P  +  
Sbjct: 1   MKGLILCAGKGSRLYPFTKNRPKTLIPVTNTPLLQLSIMKLMELGIDRIGIVIHPSQEAD 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   G+G  FGI + Y  Q +P G+A A    E +L+GEP  L+LGDN+      S   
Sbjct: 61  IRAQFGEGEAFGISITYIYQHAPKGIANALKNAEYYLSGEPFLLLLGDNLIS-APLSDLK 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
             V      A++   +V DP+ +G+ E   + R I LEEKP  PKSN AV G Y +  ++
Sbjct: 120 YDVEHGGVQASLLLAEVADPQDYGIAEI-QDSRIIGLEEKPVHPKSNLAVIGGYAFTKEI 178

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
                ++ PS+RGE EIT   Q  +E        +      +D GT D  + A+  +   
Sbjct: 179 FGAVNKITPSKRGEYEITDAIQWLIEQRYDVAYRVTDQLN-IDVGTKDRWLLANRKLLEA 237

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRARP 290
           E     +    + +      + +         L     G Y+     +R 
Sbjct: 238 E---ALQKRVHDSVQMERCTIVEPVSIDKDCVLKDCRIGPYVSVGAGSRL 284


>UniRef50_C5VTI3 Nucleotidyl transferase n=1 Tax=Clostridium botulinum D str. 1873
           RepID=C5VTI3_CLOBO
          Length = 349

 Score =  247 bits (632), Expect = 3e-64,   Method: Composition-based stats.
 Identities = 57/233 (24%), Positives = 93/233 (39%), Gaps = 12/233 (5%)

Query: 5   ILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQRL 64
           ILAGG GTRL P+T  + K +L I  KPM+   +      G    +I    +     +  
Sbjct: 125 ILAGGLGTRLRPLTENIPKPMLKIGGKPMLQRIIEQFKGYGFVNFIISLNYK-GEIIENY 183

Query: 65  LGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHVA 124
             DGS F + ++Y  +    G A +  + +   N +   LV+  +I  G  F   L+H  
Sbjct: 184 FKDGSNFDVNIQYVREEKKLGTAGSINLAKEKFNKD--FLVINGDILTGIDFEVMLKHHI 241

Query: 125 ARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEYA 184
                 T           +GV+   +N    SLEEKP    + +  +G+Y     V+ Y 
Sbjct: 242 ENKFDITAGARNYEMRVPYGVMIT-ENKIIKSLEEKPT--YNFYINSGVYVLSKNVINYI 298

Query: 185 KQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
            +       E  +T + +  ++AG            W D G  +   +A+  V
Sbjct: 299 PENT-----EYNMTDLIEDVIKAGGRCGTYNITE-YWSDIGHIEDYKKANEDV 345


>UniRef50_Q1AVJ3 Nucleotidyl transferase n=1 Tax=Rubrobacter xylanophilus DSM 9941
           RepID=Q1AVJ3_RUBXD
          Length = 367

 Score =  247 bits (631), Expect = 4e-64,   Method: Composition-based stats.
 Identities = 70/278 (25%), Positives = 109/278 (39%), Gaps = 13/278 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +IL GG GTRL PIT  + K L+P+ +KP + Y L  L   GI   ++         
Sbjct: 1   MQAVILVGGLGTRLRPITYDIPKALVPLRNKPFMGYTLDFLRGGGIEGAVLSLGY-LPDP 59

Query: 61  FQRLLGDGSEF-GIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK 119
            QR + +  +  G  +EYA +  P G A        FL   P  +VL  ++  G      
Sbjct: 60  IQRYIDERGDLDGFSVEYAVEERPLGTAGGIKNAARFLQDGP-VVVLNGDVLTGMDLRKA 118

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYD 177
           +    +    AT+    V DP  +G+VE D +       EKP   +  +N    G+Y  +
Sbjct: 119 IELHRSTGALATITLTSVEDPTAYGLVEVDHDMMVRRFIEKPSPDEVTTNLVNAGVYVLE 178

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
            +V+E         R       I     E   L   +      W D GT  S + AS  V
Sbjct: 179 PEVLEMIPPG----REVSIEREIFPRLQERRQLYAHV--SSSYWKDIGTPRSYLAASHDV 232

Query: 238 QTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAK 275
            +     G     ++    R+  ++         S+A+
Sbjct: 233 LSGAVGAGEGFDYMD--VHRSTLIEKNVRILPPVSVAE 268


>UniRef50_Q8YRP4 Mannose-1-phosphate guanyltransferase n=11 Tax=Bacteria
           RepID=Q8YRP4_ANASP
          Length = 389

 Score =  246 bits (630), Expect = 5e-64,   Method: Composition-based stats.
 Identities = 61/308 (19%), Positives = 114/308 (37%), Gaps = 37/308 (12%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +ILA G GTR+ PIT  + K ++PI  KP++ + L +L   G  +I++  +   +  
Sbjct: 1   MKAMILAAGKGTRVRPITYTIPKPMIPILQKPVMEFLLELLRQHGFDQIMVNVSHLAEE- 59

Query: 61  FQRLLGDGSEFGIQLEYAEQ----------PSPDGLAQAFIIGETFLN-GEPSCLVLGDN 109
            +    DG  FG+Q+ Y+ +              G A      + F    + + +VL  +
Sbjct: 60  IENYFRDGQRFGVQIAYSFEGKIDDEGKLVGEAIGSAGGMRRIQDFSPFFDDTFVVLCGD 119

Query: 110 IFFGQGFSPKLRHVAARTEGATVFGYQV--MDPERFGVVEFDDNFRAISLEEKP--KQPK 165
                  +  ++   ++   AT+    V   +   +GVV  D+N R  + +EKP  ++  
Sbjct: 120 ALIDLDLTAAVKWHKSKGSIATIITKTVPEEEVSSYGVVVTDENSRVKAFQEKPSIEEAL 179

Query: 166 SNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTG 225
           S    TG+Y ++ +V  Y       + G      +    +E G      +   F W+D G
Sbjct: 180 STNINTGIYIFEPEVFNYIPSGVEYDIG----GQLFPKLVEIGAPF-YAIAMDFEWVDIG 234

Query: 226 THDSLIEA----------STFVQTVEKRQGFKIACLEEIAWRN------GWLDDEGVKRA 269
                  A          +  +   E   G        + W         ++        
Sbjct: 235 KVPDYWRAIRGVLQGDIKNVQIPGHEVAPGIYTGLNVAVNWDKVDITGPVYIGGMTRIED 294

Query: 270 ASSLAKTG 277
            + +    
Sbjct: 295 GAKIVGPA 302


>UniRef50_UPI000038E164 mannose-1-phosphate guanyltransferase n=1 Tax=Ferroplasma
           acidarmanus fer1 RepID=UPI000038E164
          Length = 367

 Score =  246 bits (630), Expect = 5e-64,   Method: Composition-based stats.
 Identities = 65/271 (23%), Positives = 120/271 (44%), Gaps = 16/271 (5%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K +++AGG GTRL PIT  + K ++PI  KP + Y L     AGI++++I T  +     
Sbjct: 11  KAVVMAGGKGTRLRPITYSIPKPVVPIAGKPCMLYLLDSYYNAGIKDVIITTGYKFSSLI 70

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLR 121
             ++ +       + ++ +  P G A +  +   F+  + + +V   +I      S  + 
Sbjct: 71  TSIIEN-RHNDQAILFSVEKEPAGTAGSVKMVSNFI--DDTLIVGSGDILSDFNISDIIN 127

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP--KQPKSNWAVTGLYFYDSK 179
                    T+   +V DP +FG+VE  +N R +   EKP   Q  S+ A TG+Y  + +
Sbjct: 128 FHKKNKAMVTIVLTEVEDPRQFGIVEM-ENNRIVRFLEKPDRDQTFSHIASTGIYVIEPE 186

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           +++Y   +            +    ++        +G+   WLDTG  + LI A+  +  
Sbjct: 187 ILDYITTMPY-----DFAKDLFPELMKRNIDIYGYMGK-GVWLDTGRPNDLITANQIMVE 240

Query: 240 VEKRQGFKIACLEEIAWRNGWLDDEGVKRAA 270
               +  K + ++ I  +N  LD  G+    
Sbjct: 241 ----KYGKPSNVDFIKGKNIILDMAGIHNTG 267


>UniRef50_Q5CTS3 Mannose-1-phosphate guanylyltransferase n=2 Tax=Cryptosporidium
           RepID=Q5CTS3_CRYPV
          Length = 425

 Score =  246 bits (629), Expect = 7e-64,   Method: Composition-based stats.
 Identities = 51/255 (20%), Positives = 92/255 (36%), Gaps = 11/255 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK IIL+GG G+RL P+T    K ++ + + P+I + ++     GI EI++    +    
Sbjct: 30  MKAIILSGGYGSRLRPLTLTKPKSIVELCNIPIIEFQIAQFASIGITEIIVALNYKANEL 89

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
              L      + +++  + +  P G A    + + FL  +    V   +I         L
Sbjct: 90  IPTLKIIEDRYAVKVHLSIEEKPLGTAGPIKLAQDFLKEDEPFFVCNSDIICNFPLREML 149

Query: 121 RHVAARTEG----ATVFGYQVMDPERFGVVEFDDNFRAIS-LEEKPKQPKSNWAVTGLYF 175
                +         +   QV DP +FGVV  D+N   +    EKPK    ++   G+Y 
Sbjct: 150 DLYHKKNSDSECNGVILIKQVSDPSKFGVVLHDENTLIVEKFIEKPKDFVGDFINAGIYI 209

Query: 176 YDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTV--ELLGRGFAWLDTGTHDSLIEA 233
              ++++  K  +           +  +   +  L            W D G     +  
Sbjct: 210 LSKRILDLIKPNQ----QVSIEKDVFPIMASSNTLYCNKFFTNNDNIWADIGNPKDFLLG 265

Query: 234 STFVQTVEKRQGFKI 248
           S       K      
Sbjct: 266 SKLFMEFLKSNSITG 280


>UniRef50_B1HN58 Mannose-1-phosphate guanyltransferase 2 n=5 Tax=Bacteria
           RepID=B1HN58_LYSSC
          Length = 350

 Score =  246 bits (629), Expect = 8e-64,   Method: Composition-based stats.
 Identities = 49/241 (20%), Positives = 96/241 (39%), Gaps = 12/241 (4%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +++ GG GTRL P+T    K +L + +KP++   +      G    +     + +   Q
Sbjct: 121 VVLMLGGLGTRLRPLTNDTPKPMLRVGNKPILETIIEGFKQYGYTNFIFSVNYKKE-VIQ 179

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
               +G  F + +EY E+    G A A  + +          V+  ++     F   ++ 
Sbjct: 180 DYFQNGEAFDVTIEYIEEDKKMGTAGALSLLKK--RPTKPFFVMNGDLLTQINFDQLMQF 237

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
                  AT+   +      FGV+E +       ++EKP     ++   G+Y  +  V++
Sbjct: 238 HMEHESVATMCVREFEYQIPFGVIETNGTDLVT-IKEKPIH--RSFVNAGIYLLNPDVLD 294

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEK 242
           Y  Q +       ++ S+ +  +E  + T     R   WLD G  D   +A+  V+ +  
Sbjct: 295 YIPQDEF-----YDMPSLFEKLIEKNSKTSVFPIRE-YWLDIGQIDDFNKANNEVKELLN 348

Query: 243 R 243
            
Sbjct: 349 E 349


>UniRef50_A9CZR8 Nucleotidyl transferase n=1 Tax=Hoeflea phototrophica DFL-43
           RepID=A9CZR8_9RHIZ
          Length = 346

 Score =  246 bits (628), Expect = 9e-64,   Method: Composition-based stats.
 Identities = 58/243 (23%), Positives = 96/243 (39%), Gaps = 12/243 (4%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +I+AGG GTRL P+T  V K L+ +  +P+I   +  L+  G+  I +          +
Sbjct: 108 VVIMAGGLGTRLRPLTEKVPKPLISVGGRPLIDTIVDRLVAQGLSNITLCVNY-LGHMLE 166

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
             LGDGS +G +  Y  +    G A A  + +     E S  V+  +I            
Sbjct: 167 EHLGDGSRYGARFTYVRENKRMGTAGALSLLDK--RPETSFFVMNGDILTSVDLMAMRSF 224

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
                  AT+          FGVV+   + R   L EKP+   +     G+Y ++ +V++
Sbjct: 225 HQENNSLATMAVNNFSYEVPFGVVDV-RDRRITGLSEKPQ--CNFLVNAGIYLFEPEVLD 281

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEK 242
           +    +       ++ S     ++     V    R   WLD G  D L  A+     V  
Sbjct: 282 HVPSDEF-----FDMNSFFDRLIDLDKPIVAFPVRE-HWLDIGRPDDLERANNTFSAVAG 335

Query: 243 RQG 245
            +G
Sbjct: 336 GKG 338


>UniRef50_UPI0001C315B1 Nucleotidyl transferase n=1 Tax=Conexibacter woesei DSM 14684
           RepID=UPI0001C315B1
          Length = 329

 Score =  246 bits (628), Expect = 1e-63,   Method: Composition-based stats.
 Identities = 58/279 (20%), Positives = 108/279 (38%), Gaps = 17/279 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++LA G GTRL P+T  + K ++P+ D+P++ + + +L   G  EI+          
Sbjct: 1   MKAMVLAAGLGTRLRPLTYEIPKPMVPVLDRPVMAHIVDLLERHGYGEIVANLHY-FPDT 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GD      ++ Y E+P   G A        FL  + + L++  +       +  +
Sbjct: 60  IRAYFGD------RIVYREEPELLGTAGGVRNCADFLADD-TFLIISGDALTDIDLTRFV 112

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
           +        AT+   +V D   FGVV  DD  R    +EKP+  +  S+    G+Y ++ 
Sbjct: 113 KRHKEAGGVATLAVKRVADTREFGVVLHDDTGRITGFQEKPEPAEALSDLGNCGIYLFEP 172

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           ++ +Y       +        +    L   ++   +      W D G+   L + +    
Sbjct: 173 RIFDYFPDQPFVDWA----NDVFPALLAQ-DVPFHIHEIDEYWNDVGSLGELKDGTFDAM 227

Query: 239 TVEKRQGFKIA--CLEEIAWRNGWLDDEGVKRAASSLAK 275
             E     +      + IA     LD   +      L +
Sbjct: 228 RGELHLEVEGEPVAEDVIAGEGTSLDGATLIEPPVWLGR 266


>UniRef50_A0ADR0 Putative nucleoside-diphosphate-sugar pyrophosphorylase n=1
           Tax=Streptomyces ambofaciens ATCC 23877
           RepID=A0ADR0_STRAM
          Length = 254

 Score =  245 bits (626), Expect = 1e-63,   Method: Composition-based stats.
 Identities = 61/260 (23%), Positives = 101/260 (38%), Gaps = 12/260 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ ++LAGG G RL P T  V K L+PI   P+++  L+ L  AG   + +         
Sbjct: 1   MRAVVLAGGEGRRLRPATLTVPKPLMPIDGIPILHIILTQLKNAGFTRVTLSLGYRAH-M 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   G     G++L+++ +  P G A    +   F   E S LV+  ++     F+   
Sbjct: 60  IRASFGGNRWSGLELDFSLEEEPLGTAGPLALLPPF---EESVLVMNADLLTDVDFADLW 116

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
            H       AT+           GVVE D+  R     EKP+   S     G+Y  +  +
Sbjct: 117 SHHKKSRAAATIALSPQDIDVAHGVVELDEERRVTDFREKPR--LSFLVSGGIYVLEPSL 174

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           + +        RG  ++ ++       G      +     W D GT + L  A+T  +T 
Sbjct: 175 LRFLPP-----RGRHDMPTLLDHARAHGERVEGYVI-EGDWRDIGTPEQLDLATTAFRTD 228

Query: 241 EKRQGFKIACLEEIAWRNGW 260
             R   +    E  A    +
Sbjct: 229 RARYLGRRGVAELCAGTGAF 248


>UniRef50_Q3Z925 Glucose-1-phosphate thymidylyltransferase n=5 Tax=Dehalococcoides
           RepID=Q3Z925_DEHE1
          Length = 393

 Score =  245 bits (626), Expect = 1e-63,   Method: Composition-based stats.
 Identities = 73/279 (26%), Positives = 116/279 (41%), Gaps = 17/279 (6%)

Query: 1   MK-GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKG 59
           MK  +ILA G G RL P T   SK +L I  KP++ Y +  L   GIR+I+++   + + 
Sbjct: 1   MKQAVILAAGEGQRLRPFTSSKSKVMLSIAGKPLLEYVIESLARNGIRDIILVVGYKRER 60

Query: 60  YFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK 119
            F    GDG   G+++ Y  QP+  G A A       + G+   LVL  +       +  
Sbjct: 61  IF-DYFGDGGHLGVEITYVSQPNQLGTAHALKQTRDKIRGD--FLVLNGDQL--ISPATI 115

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSK 179
              V    +   V      DP R+GVV      R  S+EEKP   KSN   TG+Y + ++
Sbjct: 116 GDFVKEPPQAVMVKAINGEDPRRYGVVSSSGR-RLTSIEEKPSIAKSNLINTGIYSFSTR 174

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           V +Y  +        L+I  + Q  ++ G L + +      WLD      ++  +  V  
Sbjct: 175 VFDYIAE-------HLDIPMVLQSMIKDG-LDIRVAESRGVWLDIVYPWDMLSLNAVVSD 226

Query: 240 VEKRQGFKIACLEEIAWRNGW-LDDEGVKRAASSLAKTG 277
              + G        +  +    +    V R+ S +    
Sbjct: 227 TL-KPGVAGTIESGVVMKGPVLIGKNTVIRSNSYITGPV 264


>UniRef50_A9A1Q3 Glucose-1-phosphate thymidyltransferase n=1 Tax=Nitrosopumilus
           maritimus SCM1 RepID=A9A1Q3_NITMS
          Length = 351

 Score =  244 bits (625), Expect = 2e-63,   Method: Composition-based stats.
 Identities = 91/278 (32%), Positives = 137/278 (49%), Gaps = 5/278 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKGIIL GG GTRL P+T    KQLLPI +KPM  Y +  +  AGI EI II        
Sbjct: 1   MKGIILHGGHGTRLRPLTHTGPKQLLPIANKPMSQYCIESMKNAGITEIAIIIGGIASKK 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   G+G +FG+++ Y  Q +P G+A A  + + F+  +   + LGDNI   +    K 
Sbjct: 61  VEEYYGNGEKFGVKITYISQEAPKGIAHAINLCKDFVKDDKFLVFLGDNILKKEILEYKT 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
            +       A +   +V +P +FG+ +  DN + I + EKPK P +N AVTG+YF + K+
Sbjct: 121 NY-ENSDADALLLLCEVDNPTQFGIADVKDN-KIIKIMEKPKDPPTNLAVTGIYFLNKKI 178

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            E    +KPS R ELEIT   Q+ +E GN  +        W DTGT + ++ A+  +   
Sbjct: 179 FEIIDILKPSWRNELEITDALQLLMEKGNKIIFDTVTD-YWKDTGTPNDILHANKEILQD 237

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
             ++   +   E+       +  E        +     
Sbjct: 238 ISQE--FLGEKEQTQIDGVCVLKEKSLLKNVKIIGPVL 273


>UniRef50_Q4UEZ4 GDP-mannose pyrophosphorylase, putative n=2 Tax=Theileria
           RepID=Q4UEZ4_THEAN
          Length = 389

 Score =  244 bits (625), Expect = 2e-63,   Method: Composition-based stats.
 Identities = 55/293 (18%), Positives = 102/293 (34%), Gaps = 25/293 (8%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIIT--TPEDK 58
           MK +ILAGG GTR+ P+T  V K L+   ++P+I + +     AG   ++I         
Sbjct: 1   MKSVILAGGYGTRIRPLTLSVPKPLVDFCNRPVIEHQIQACKNAGFDHVIIAVTEHHNIT 60

Query: 59  GYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFL---NGEPSCLVLGDNIFFGQG 115
              + L     ++ I+++++ + +P G A    + +  +   +     +V   +I     
Sbjct: 61  EPIKNL---AEKYSIRIDFSTESTPLGTAGPLRLAKDLICSDDDSDDFVVFNSDIICNYP 117

Query: 116 FSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYF 175
               L     ++   T+    V +   FGV+  D+N    S  EKPK   SN    G+Y 
Sbjct: 118 LKELLESHRKKSAKVTIMVTTVENSSEFGVILHDENGLIKSFLEKPKNATSNTINAGVYV 177

Query: 176 YDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAST 235
              +V+++      S             YL+    +  +      W D G     +    
Sbjct: 178 LSKEVLDHIPLKNYSIE-----KQFFPKYLK--YNSSYIYKLNGFWSDIGKPTGYLNGQN 230

Query: 236 FVQTVEKRQGF----------KIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
              +  +                     I+  N +  D   K   +       
Sbjct: 231 LFLSHVQGLEANSCKSNHDLRDGDFSPLISAENSFETDSSYKSTETKFRHPVL 283


>UniRef50_Q3SPZ3 Nucleotidyl transferase n=1 Tax=Nitrobacter winogradskyi Nb-255
           RepID=Q3SPZ3_NITWN
          Length = 346

 Score =  244 bits (625), Expect = 2e-63,   Method: Composition-based stats.
 Identities = 55/238 (23%), Positives = 108/238 (45%), Gaps = 12/238 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +++AGG G+RL P+T  + K L+ + +KP++   L+  + +G  +  I    + +   +
Sbjct: 119 VVLMAGGLGSRLRPLTDDLPKPLIKVGNKPILETVLNGFIKSGFGKFFISVNYKAE-MIR 177

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
              GDGS +G++++Y  +    G A A  +            V+  ++     F   L++
Sbjct: 178 EYFGDGSAWGVEIDYLVESDRLGTAGALSLIPE--RPTRPFFVMNGDLLTTVNFEQMLKY 235

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
                   T+   +      FGVV+F ++ R + + EKP Q    +   G+Y  D +V++
Sbjct: 236 HLEHQAFTTICVREHAITVPFGVVDF-EDHRILGIREKPTQ--KFFVNAGVYLLDPEVLD 292

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           Y    +  +     + ++ +  +E G  +V    R   W+D G  D L +AS   Q +
Sbjct: 293 YIGATEAVD-----MPTLIERTIERGKRSVAFPLRE-YWIDVGRLDDLQKASDEFQRI 344


>UniRef50_A0L542 Nucleotidyl transferase n=2 Tax=Proteobacteria RepID=A0L542_MAGSM
          Length = 351

 Score =  244 bits (625), Expect = 2e-63,   Method: Composition-based stats.
 Identities = 49/236 (20%), Positives = 95/236 (40%), Gaps = 11/236 (4%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +++AGG G+RL  +TR   K LL +  +P++   +   +  G  +  +    + +   +
Sbjct: 124 VVLMAGGLGSRLGELTRDCPKPLLHVGKQPILEMIIENFVSYGFHKFYLAVNYKKE-MIK 182

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
              GDGS  G+++EY E+    G A    +       +    V+  ++     F   L +
Sbjct: 183 AYFGDGSRLGVRIEYLEEEQRLGTAGPLSLMPEA--PKDPFFVMNGDLLTRIHFGRVLDY 240

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
              +   AT+   QV +   +GVV+  +N R   + EKP      +  TG+Y  +  V+ 
Sbjct: 241 HRQQQADATMCVRQVEETLPYGVVDLGENHRLNGITEKPVN--RYFVNTGIYLLEPHVLP 298

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
              +         ++  + +   + G   V        W+D G      +A   V+
Sbjct: 299 IIPK-----GQFFDMPDLFRSLADEGKHPVAFPFLE-YWMDIGQVGDFHQACRDVK 348


>UniRef50_Q2FRV9 Nucleotidyl transferase n=7 Tax=cellular organisms
           RepID=Q2FRV9_METHJ
          Length = 401

 Score =  244 bits (624), Expect = 3e-63,   Method: Composition-based stats.
 Identities = 66/276 (23%), Positives = 115/276 (41%), Gaps = 15/276 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +ILA G G R+ P+T    K +LP+  +PM+ + L+ +M AGI + + +     +   +
Sbjct: 4   CVILAAGEGKRMRPLTGSRPKVMLPLAGRPMLEHLLNAVMDAGITDFIFVVGY-GEASVR 62

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDN-IFFGQGFSPKLR 121
              GDG+  GI + Y  Q    G   A +     ++ +   L+L  + +         L 
Sbjct: 63  NFFGDGTSKGISIRYVTQKRQQGTGDALMTVRPHVHSQ--FLLLNGDMVLHSDDIKAML- 119

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVV 181
               +T    +  +    P+ +GVV  D +     LEEK   PKS+    G+Y ++  + 
Sbjct: 120 ----KTPAPAMGVFTSNHPQDYGVVTMDGD-IITGLEEKSLHPKSDLINAGMYLFEPGIF 174

Query: 182 EYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVE 241
           E  + ++PS RGELE+T     Y++   L    L     W D G+   L+     +   E
Sbjct: 175 EELETIRPSPRGELELTDALMTYIQNKTLRGVRLSF---WADMGSPWDLLGVHEEM-MRE 230

Query: 242 KRQGFKIACLEEIAWRNGW-LDDEGVKRAASSLAKT 276
                +    E +  +    +    V  + S L   
Sbjct: 231 IIPEHQGVIEEGVIIKGDVQIGSGTVIMSGSYLEGP 266


>UniRef50_B9LMT7 Nucleotidyl transferase n=2 Tax=Halobacteriaceae RepID=B9LMT7_HALLT
          Length = 391

 Score =  244 bits (624), Expect = 3e-63,   Method: Composition-based stats.
 Identities = 61/284 (21%), Positives = 122/284 (42%), Gaps = 17/284 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            ++LA G G RL P+T    K ++P+ ++P++ + +  +  AGI  I ++     +   +
Sbjct: 8   AVVLAAGEGRRLEPLTNRRPKPMVPVANRPLLEHVVEAVAAAGINRIALVVGYR-QERIR 66

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
              GDG ++G+ +EY EQ +  G   A +  E  ++G    +VL  +         ++R 
Sbjct: 67  NHFGDGDDWGVTIEYVEQSTQLGTGHAVLQAEPVVDG--PFVVLNGDRIVDAAVVSRVRD 124

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQP-KSNWAVTGLYFYDSKVV 181
           +A   +   +       P  +GVV  D + R   ++EKP+ P ++N    G+Y +   V 
Sbjct: 125 LARDGDHPAMAVTTAERPREYGVVTLDGD-RVTGIDEKPEGPVETNRINAGVYAFSPAVF 183

Query: 182 EYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV---- 237
           +  ++      GEL IT+       AG+LT   +G    WLD      L+  +  +    
Sbjct: 184 DAIRET--HTTGELAITATLNELASAGDLTA--VGYDGRWLDVSNLWDLLGVNAALIGES 239

Query: 238 ---QTVEKRQGFKIACLEEIAWRNGW-LDDEGVKRAASSLAKTG 277
              +  +   G  +   +++A      +        ++++    
Sbjct: 240 EQTEPTDAAFGASVTVADDVALAGNVRIGPNVTVGGSTAIGSNA 283


>UniRef50_B9LW43 Nucleotidyl transferase n=5 Tax=Halobacteriaceae RepID=B9LW43_HALLT
          Length = 402

 Score =  244 bits (624), Expect = 3e-63,   Method: Composition-based stats.
 Identities = 71/295 (24%), Positives = 122/295 (41%), Gaps = 15/295 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M G++LA G GTR+ P+T    K LLP+ D+ ++       +      ++ +T       
Sbjct: 1   MYGVVLAAGRGTRMRPLTDRRPKPLLPVGDRSLLEQVFDTAVDVVDEFVV-VTGYR-GDA 58

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  +G+       + Y EQ    G A A       ++ +   LVL  ++         L
Sbjct: 59  IRESIGESYR-DRPVTYVEQEEAKGTAHAIAQAAPVVDDD--FLVLNGDVVVDASLPRVL 115

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
               A  +G  V   +V+DP  +GV+    +     + EKP  P +N A  G Y +  +V
Sbjct: 116 ----ANADGPAVAATEVIDPRAYGVLSTAADGSLTKIVEKPANPPTNLANVGCYAFTPEV 171

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            EY  +   SERGE EIT+  ++ L+ G+   ++      WLD G    L+EA+    T 
Sbjct: 172 FEYIDRTPESERGEYEITTTIELLLDDGHRI-DVAPYVGTWLDVGRPWELLEANELALTE 230

Query: 241 EKRQGFKIACLEEIAWRNG--WLDDEGVKRAASSLAKTGYGQYLLELLRARPRQY 293
                     +E+    +G   ++D  + R+ + +        + E     P  Y
Sbjct: 231 LGSDEAIAGTVEKGVHLHGSVVVEDGALVRSGAYIEGPVL---IREGAEVGPNAY 282


>UniRef50_B1XM99 Sugar-phosphate nucleotidyl transferase n=59 Tax=cellular organisms
           RepID=B1XM99_SYNP2
          Length = 409

 Score =  244 bits (623), Expect = 3e-63,   Method: Composition-based stats.
 Identities = 63/293 (21%), Positives = 109/293 (37%), Gaps = 24/293 (8%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +ILA G GTR+ PIT  + K L+PI  KP++ + L +L   G  +I++  +      
Sbjct: 1   MKAMILAAGKGTRVRPITYTIPKPLIPILQKPVMEFLLDLLAQHGFDQIMVNVSHLAHE- 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPS---------PDGLAQAFIIGETFLN-GEPSCLVLGDNI 110
            +    DG  +G+ L Y+ + S           G A      + F    + + +VL  + 
Sbjct: 60  IEGYFKDGQRYGVHLAYSFEGSIQDGELQGAALGSAGGLRKIQDFHPFFDDTFVVLCGDA 119

Query: 111 FFGQGFSPKLRHVAARTEGATVFGYQVMD--PERFGVVEFDDNFRAISLEEKPK--QPKS 166
                 +  +R    +   ATV    V       +GVV  DD  R +S +EKP   +  S
Sbjct: 120 LIDLDLTAAVRWHREKGAIATVITKSVPKEAVSSYGVVVTDDEDRILSFQEKPSVTEALS 179

Query: 167 NWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGT 226
               TG+Y ++ +V+++       + G      +    + A       L   F W+D G 
Sbjct: 180 TKINTGIYIFEPEVIDFIPPNCEFDIG----GQLFPKLVAANAPF-YALDMDFEWVDIGK 234

Query: 227 HDSLIEASTFVQTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASS-LAKTGY 278
                +A   V   + +    +           +             +    Y
Sbjct: 235 VPDYWQAIQSVLQGKIKN---VPIPGIEVKPGVYTGLNVAVNWDKVEIQGPVY 284


>UniRef50_D2EEI5 Nucleotidyl transferase n=1 Tax=Candidatus Parvarchaeum acidiphilum
           ARMAN-4 RepID=D2EEI5_9EURY
          Length = 273

 Score =  244 bits (623), Expect = 3e-63,   Method: Composition-based stats.
 Identities = 54/237 (22%), Positives = 101/237 (42%), Gaps = 13/237 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +ILAGGSGTRL P+T  + K ++ +  +P++ + +  L  A   +I+I          +
Sbjct: 49  ALILAGGSGTRLRPLTYEIPKPMMLVNGRPILEHIIEQLKKAEFVDIIISIGY-LGSRIK 107

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
              GDGS+FG+++ Y+E+ +P G   A    +     +   +VL  +  F    +     
Sbjct: 108 EYFGDGSKFGVRIRYSEETTPVGTGGAIKKNQNLFQED--FIVLNGDNLFDFDLNKIYEF 165

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK-QPKSNWAVTGLYFYDSKVV 181
                  AT+         +FGVVE + N + +   EKPK +  S+    G+Y  +   +
Sbjct: 166 HKKEKAMATIALVLRDGVSQFGVVEMEGN-KIVKFIEKPKIEQVSHLVNAGIYVINPAFL 224

Query: 182 EYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
            +         GE  I+++ +  +E     ++       WL   + +   +A     
Sbjct: 225 SFIPS------GESNISNVFEKVVEK--RIIDGFIYSGKWLPCDSIELYEKAIKNWP 273


>UniRef50_C4SU82 Nucleoside-diphosphate-sugar pyrophosphorylase involved in
           lipopolysaccharide biosynthesis/translation initiation
           factor 2B, gamma/epsilon subunits n=4 Tax=Yersinia
           RepID=C4SU82_YERFR
          Length = 387

 Score =  243 bits (621), Expect = 6e-63,   Method: Composition-based stats.
 Identities = 59/267 (22%), Positives = 109/267 (40%), Gaps = 24/267 (8%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +ILA G GTR  P+T  + K ++P+  KP++   +  L   G  ++++ T+      
Sbjct: 1   MKAMILAAGKGTRARPLTTILPKPMIPLIRKPIMESIIEHLRKYGFNQLMVNTSYLSAD- 59

Query: 61  FQRLLGDGSEFGIQLEYAEQ---------PSPDGLAQAFIIGETFLN-GEPSCLVLGDNI 110
            +    DG  +G+++ Y+ +          +  G A      + F    + + +V+  + 
Sbjct: 60  IENYFRDGHAWGVEIGYSYEGVMEGNTFVDNVLGSAGGMKHIQNFSGFFDETFVVVCGDA 119

Query: 111 FFGQGFSPKLRHVAARTEGATVFGYQV--MDPERFGVVEFDDNFRAISLEEKP--KQPKS 166
                F   L    AR   AT+    V      ++G+V  D+  R    +EKP  +   S
Sbjct: 120 LIDVDFDEVLAFHRARKSVATLVIRPVSADQVNKYGIVVTDEQGRVSQFQEKPKTEDALS 179

Query: 167 NWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGT 226
           N A TG+Y ++ ++ +Y       +  E +I S     L    +    +   F W+D G+
Sbjct: 180 NNANTGIYVFEPEIFDYIP-----DGVEYDIGSQLFPKLAELGIPFYGIASPFQWVDIGS 234

Query: 227 HDSLIEASTFVQTVE----KRQGFKIA 249
                  +  +   +       G KIA
Sbjct: 235 LQDFWHVNRMILNQDLPDYPMPGIKIA 261


>UniRef50_B0BLL5 dTDP-1-glucose synthase n=1 Tax=Actinomadura madurae
           RepID=B0BLL5_9ACTO
          Length = 344

 Score =  243 bits (620), Expect = 7e-63,   Method: Composition-based stats.
 Identities = 78/280 (27%), Positives = 127/280 (45%), Gaps = 4/280 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++LAGG+ +RL P +  + KQL+P+  +P++ + L  +   G+R+  I+        
Sbjct: 1   MKALVLAGGTASRLRPFSNSLPKQLIPLAGRPVLEHVLRGIADIGVRDTAIVVGDTAPA- 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
               +GDG+  G+++ Y  Q  P GLA    +   FL  +   + LGDN+  G G +   
Sbjct: 60  VMDAIGDGARLGLRVTYVPQARPLGLAHCVTLARPFLGDDDFVMYLGDNLLPG-GIAGPA 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           R    R   A +   +V DP  FGV E   +     LEEKP  P+++ AV G+YF+ S V
Sbjct: 119 RRFRDRRPSAQLLLRRVADPRAFGVAEVGRDGVVRRLEEKPAHPRTDLAVLGVYFFTSAV 178

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ-T 239
                  +PS RGELEIT   Q+ ++ G  TV  +     W D G    ++  +  +   
Sbjct: 179 HAAIDACRPSHRGELEITDAIQVLIDRGR-TVRAVEHTGHWRDIGRPADVLACNRRLLAE 237

Query: 240 VEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYG 279
           +  R    +    E+      ++       +        G
Sbjct: 238 LRPRTDGDLDAATEVTGGPVVIEPGARVVRSRITGPALVG 277


>UniRef50_C0G2T6 Nucleotidyl transferase n=1 Tax=Natrialba magadii ATCC 43099
           RepID=C0G2T6_NATMA
          Length = 417

 Score =  243 bits (620), Expect = 8e-63,   Method: Composition-based stats.
 Identities = 66/293 (22%), Positives = 124/293 (42%), Gaps = 14/293 (4%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            ++LA G G RL P+T    K ++P+ ++P++ Y +S L  AGI  I+++     +   +
Sbjct: 34  AVVLAAGEGRRLDPLTNRRPKPMVPVANRPILDYVVSALAGAGIDRIVLVVGYR-QERIR 92

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
              GDG ++ + +EY  Q +  G A A +  E  ++G    LVL  +         ++R 
Sbjct: 93  NYFGDGDDWDVDIEYVVQETQLGTAHAVLQAEEVVDG--PFLVLNGDRIVDPALVSQVRD 150

Query: 123 VAARTEG-ATVFGYQVMDPERFGVVEFDDNFRAISLEEKP-KQPKSNWAVTGLYFYDSKV 180
             A       +   +      +GVV  + N R   + EKP    +S     G+Y + + +
Sbjct: 151 AVATDADRPVLSVTRSAHASDYGVVSLEGN-RVTGITEKPIAPARSELINAGVYGFANDI 209

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            E  ++  P+E GEL IT+  +  L     +   +     WLD      L++ +  +   
Sbjct: 210 FEAIRET-PTEEGELAITTTLETILAD--RSASAVQEHDIWLDVSYLWDLLDVNAAILGD 266

Query: 241 EKRQGFKIACLE-EIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRARPRQ 292
           ++ +  + + LE E+A          +   A+    T  G      +  +P  
Sbjct: 267 DEFETTQESTLEGEVATDTAIGTAVSLGANATVGGSTALGD----NVTIQPNA 315


>UniRef50_UPI0001693120 glucose-1-phosphate thymidyltransferase n=1 Tax=Paenibacillus
           larvae subsp. larvae BRL-230010 RepID=UPI0001693120
          Length = 338

 Score =  243 bits (620), Expect = 8e-63,   Method: Composition-based stats.
 Identities = 82/281 (29%), Positives = 139/281 (49%), Gaps = 7/281 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+IL  G GTRL P T    K +LP+  +P+I   ++ ++  GI EI I+     +G 
Sbjct: 1   MKGLILCAGQGTRLQPFTYARPKCMLPVNGEPVIVSIINKMVHIGICEIGIVINA-SQGQ 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
              +LG G  +   L Y  Q +  GLA A     +F+ GEP  L+LGDN+  G    P +
Sbjct: 60  IPAMLGSGEAYRCSLTYLLQENSLGLADAVKSAYSFIQGEPFLLILGDNLIEG-SIMPLI 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
             + +    A++    V +P +FGV +   N + + LEEK + P S+ AV G Y ++S +
Sbjct: 119 DFLGSEKADASLLLAHVKNPHQFGVADVSIN-KVVRLEEKSQNPSSDLAVVGAYAFNSDI 177

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            +   +++PS+RGE E+T   Q+ ++ G      +     + D GT +  ++A+ +  + 
Sbjct: 178 WKILDRLEPSKRGEYELTDAIQLLIDQGKHVAYCITTE-PFFDIGTPERWLDANRYKVSK 236

Query: 241 EKRQ---GFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
           + R+     ++    + A  +    D  VK   S +    Y
Sbjct: 237 DSRKQNIKKQLFHSTDTAIISPVHIDPSVKLYQSVIGPYVY 277


>UniRef50_B5HPZ4 Nucleotide phosphorylase n=1 Tax=Streptomyces sviceus ATCC 29083
           RepID=B5HPZ4_9ACTO
          Length = 365

 Score =  242 bits (619), Expect = 9e-63,   Method: Composition-based stats.
 Identities = 67/281 (23%), Positives = 110/281 (39%), Gaps = 13/281 (4%)

Query: 1   MK-GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKG 59
           M+  IIL GG GTRL P+T    K LL +     I + ++ LM AG+  ++  T+     
Sbjct: 1   MQEAIILVGGKGTRLRPLTNHTPKPLLGVAGSSFIRHQIAKLMDAGVEHVVFATSY-LAS 59

Query: 60  YFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNG--EPSCLVLGDNIFFGQGFS 117
            F+    D +   +++ YA +  P G   A       L+G  + S LVL  +I  G   +
Sbjct: 60  LFEEEFKDFTR-ELKISYAVEEVPLGTGGAIRNAARLLDGPADASVLVLNGDILSGVDLN 118

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP---KQPKSNWAVTGLY 174
             L   A R    T+   +V DP  FG+V  D + R +S  EKP   ++  ++    G Y
Sbjct: 119 ALLERHAEREAEVTLHLTRVPDPRAFGLVPTDGSGRVLSFLEKPKTAEECVTDKINAGCY 178

Query: 175 FYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
            +   V++      P++R            +  G            W D GT  + +  S
Sbjct: 179 VFRRSVLDAI----PADREVSVEQETFPQLVARGGRVFGHTTDD-YWRDLGTPLAFVHGS 233

Query: 235 TFVQTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAK 275
             + T +          E +      +D        S++  
Sbjct: 234 ADLVTGKAASPLVGRPAEALVHPTAVVDPTARVTGGSTIGP 274


>UniRef50_B7XJS8 Mannose-1-phosphate guanyltransferase n=1 Tax=Enterocytozoon
           bieneusi H348 RepID=B7XJS8_ENTBH
          Length = 329

 Score =  242 bits (619), Expect = 9e-63,   Method: Composition-based stats.
 Identities = 56/284 (19%), Positives = 117/284 (41%), Gaps = 16/284 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +IL GG GTRL+P+T+   K L+P  +KP+I Y + +L+ AGI+ I++           
Sbjct: 6   AVILVGGKGTRLYPLTKTRPKPLIPFLNKPIIEYQIDLLVEAGIQRIILALNYFSDQIKH 65

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
           + L   + + I++ Y+ +  P G A    + E ++NG  + +V+  +I+     +  +  
Sbjct: 66  KALEWKANYNIEIIYSHELEPLGTAGPLKLAEKYINGN-AFIVMNADIYTSINLTSMITE 124

Query: 123 VA-ARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDSK 179
               +   A + G +V +P+++G++E   N    +  EKP      +N    G+Y ++  
Sbjct: 125 FKTKKNYDAILLGVEVDNPDKYGLIEI-KNGTVTNFIEKPSYTNGPTNIINGGIYIFNRN 183

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           ++ + +    S   E     I    ++   +T+        W D G  +  ++       
Sbjct: 184 ILNFIELKYVSIEKE-----IFPQLVQNQKMTI--FHFNGIWCDIGVPNEYLKGQKKALG 236

Query: 240 VEKRQGFKIACL----EEIAWRNGWLDDEGVKRAASSLAKTGYG 279
                   +         I  +N  + +  +      +     G
Sbjct: 237 NTNTSNVILGKNIKMGTNIKLKNCTIFNNTIIEDNCIIENAIIG 280


>UniRef50_Q5HT82 Nucleotidyltransferase family protein n=11 Tax=Campylobacter
           RepID=Q5HT82_CAMJR
          Length = 341

 Score =  242 bits (619), Expect = 9e-63,   Method: Composition-based stats.
 Identities = 45/235 (19%), Positives = 97/235 (41%), Gaps = 13/235 (5%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQR 63
           II+AGG G+RL  +T+   K +L +  KP++   +  L        +     +     + 
Sbjct: 120 IIMAGGLGSRLKELTKDTPKPMLKVGKKPILESIVQRLKNQNFENFIFCVNYKK-QIIED 178

Query: 64  LLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHV 123
               G +FG+++ Y ++    G A A  + +       S LV+  +I     F+  L+  
Sbjct: 179 YFQKGQKFGVKISYIKERKKLGTAGALSLIKQEFK--ESFLVMNADILTELDFNDLLKAH 236

Query: 124 AARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEY 183
                  +V   +      +GV+         ++EEKP Q        G+Y  +++++  
Sbjct: 237 KKSKALMSVCVREFEQQIPYGVI-TQKQGFIENIEEKPTQ--KFLVSAGIYVLENEILNL 293

Query: 184 AKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
             + +      L++  + ++ L+ G +   ++     W+D G  D  ++A+   +
Sbjct: 294 IAKNEY-----LDMPELIKLVLQKGKVNTYII--NDYWIDIGRPDEFLKANEDFK 341


>UniRef50_P39629 Spore coat polysaccharide biosynthesis protein spsI n=88
           Tax=cellular organisms RepID=SPSI_BACSU
          Length = 246

 Score =  242 bits (618), Expect = 1e-62,   Method: Composition-based stats.
 Identities = 106/244 (43%), Positives = 151/244 (61%), Gaps = 4/244 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+ILAGG+G+RL P+T+ V+K LLP+   PMIY+ +  L  AGI++IL+I+  E    
Sbjct: 1   MKGVILAGGNGSRLMPLTKAVNKHLLPVGPYPMIYWSIMKLQEAGIKDILLISQKEHMPQ 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F +LLG+G E G+ + Y  QP+  G++      + F   E   L+LGDNIF      P  
Sbjct: 61  FYKLLGNGEELGVTITYQVQPAASGISDGLSYAKRFTKKESFILLLGDNIFED-SLKPYT 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDD-NFRAISLEEKPKQPKSNWAVTGLYFYDSK 179
                + +GA V   +V DPERFG+ E D+ N R  S+ EKP+QP +N  VTG+Y YD++
Sbjct: 120 ERFEQQGKGAKVLLKEVDDPERFGIAEIDEKNKRIRSIIEKPEQPPTNLCVTGIYMYDAE 179

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           V  Y +Q+ PS+RGELEIT +N +Y+E   LT ++L     W+D GTH+SL  AS  V  
Sbjct: 180 VFSYIEQISPSKRGELEITDVNNLYIENSQLTYDVL--SGWWVDAGTHESLYLASQLVHQ 237

Query: 240 VEKR 243
             ++
Sbjct: 238 ALRK 241


>UniRef50_D0RRF5 Glucose-1-phosphate thymidylyltransferase (DTDP-glucosesynthase)
           (DTDP-glucose pyrophosphorylase) n=1 Tax=alpha
           proteobacterium HIMB114 RepID=D0RRF5_9RICK
          Length = 294

 Score =  241 bits (616), Expect = 2e-62,   Method: Composition-based stats.
 Identities = 125/288 (43%), Positives = 174/288 (60%), Gaps = 1/288 (0%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           KGIILAGG GTRL PIT+  +KQLLPIYDKP+ +YPLS+LMLA IR IL+I     K  F
Sbjct: 4   KGIILAGGKGTRLSPITKSTNKQLLPIYDKPLFFYPLSILMLADIRNILLIINKGQKKNF 63

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLR 121
             ++GDG   G+++ Y EQ  P G+ +AF IG+ F+      L+LGDN F+GQ  +  L+
Sbjct: 64  INVVGDGRHLGLKISYEEQLKPSGIPEAFKIGKKFIGNSNVSLILGDNFFYGQSLTELLQ 123

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVV 181
                 +G TVF   V  PE +GV +  D  + + + EKPK+  S+ A+TGLYF+D+ VV
Sbjct: 124 TTKVFKKGCTVFLKGVSKPENYGVAKIKDK-KIVEIIEKPKKFISDKAITGLYFFDNHVV 182

Query: 182 EYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVE 241
           + A ++KPS+R E EI  + + Y +   L    LGRG  W D G  D     S FV +VE
Sbjct: 183 QIAHKLKPSKRKETEIVDVIKNYKKRNCLNFIELGRGAIWSDAGKIDDFTNISNFVTSVE 242

Query: 242 KRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRAR 289
           K QG KIACL+EIA++  W+  + + +      +  Y  YL +++   
Sbjct: 243 KVQGIKIACLDEIAYQKKWITKKQILKNIKFYGECPYSNYLRKIINNE 290


>UniRef50_Q6MME9 Mannose-1-phosphate guanyltransferase n=1 Tax=Bdellovibrio
           bacteriovorus RepID=Q6MME9_BDEBA
          Length = 350

 Score =  241 bits (616), Expect = 2e-62,   Method: Composition-based stats.
 Identities = 48/237 (20%), Positives = 96/237 (40%), Gaps = 12/237 (5%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K +++AGG G RL P+T  V K LL +  +P++   L      G    + +     +   
Sbjct: 121 KVVLMAGGFGKRLSPLTDSVPKPLLRVGGRPILETILMRFCELGFYNFIFVVNYRAE-MI 179

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLR 121
           +    +G ++G  +EY  +  P G      +            V+  +I     F+  L 
Sbjct: 180 KEYFQNGEKWGATIEYLHEEIPLGTCGGLSLLSE--KPSSPIFVMNGDILTRANFAEMLD 237

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVV 181
             A+    AT+   + +    +GVV+ + +   +S+EEKPK+    +   G+Y    + +
Sbjct: 238 FHASSMATATMVVREHIIEIPYGVVKVNGD-EIVSIEEKPKE--KTFVNAGIYILSPEAL 294

Query: 182 EYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           EY  + +       ++ S+     +   L      +   W+D G  +   +A +  +
Sbjct: 295 EYIPRDQF-----YDMPSLFMSLKDKEKLIQSFKLKD-YWVDIGRLEDFHKAQSDFE 345


>UniRef50_A9B2A2 Nucleotidyl transferase n=1 Tax=Herpetosiphon aurantiacus ATCC
           23779 RepID=A9B2A2_HERA2
          Length = 326

 Score =  241 bits (615), Expect = 3e-62,   Method: Composition-based stats.
 Identities = 63/291 (21%), Positives = 103/291 (35%), Gaps = 14/291 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +IL GG GTRL P+T  + K L+PI  + ++   L  L   G+R +++      + +
Sbjct: 1   MRAVILVGGLGTRLRPLTNQLPKPLVPIAGEALMSRTLRRLYKQGVRHVILAVQYLAEQF 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETF--LNGEPSCLVLGDNIFFGQGFSP 118
                GDG+ FG+ L+  ++P   G A A         L      LVL  +       + 
Sbjct: 61  LAAY-GDGAAFGLDLQIVQEPEALGTAGAVRYALDQTNLLKAGPILVLNGDELTDFDVAQ 119

Query: 119 KLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFY 176
             +        AT+   QV D   FGVV  D N R  + +EKP      +N   +G Y +
Sbjct: 120 LWQAHGQFGGVATIAVRQVADTSAFGVVASDANQRVYAFQEKPAAGTALANTINSGAYVF 179

Query: 177 DSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTF 236
           +   +        +    +    +    L    L            D GT    + A+  
Sbjct: 180 EPAALAQIPAQGFA----MLERDLFPSLLATQALIYAY-QHNAYSQDIGTLAGYLAANEA 234

Query: 237 VQT----VEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLL 283
           V       E   G + A     A          +       +    G++  
Sbjct: 235 VLLGHLPHETVHGIQYAAGVWAAADAQISPSAQLIAPIMLGSGCVVGEHAR 285


>UniRef50_B9CMC2 Glucose-1-phosphate adenylyltransferase n=1 Tax=Atopobium rimae
           ATCC 49626 RepID=B9CMC2_9ACTN
          Length = 381

 Score =  240 bits (613), Expect = 5e-62,   Method: Composition-based stats.
 Identities = 62/270 (22%), Positives = 102/270 (37%), Gaps = 26/270 (9%)

Query: 1   MK-----GIILAGGSGTRLHPITRGVSKQLLPIYDK-PMIYYPLSVLMLAGIREILIITT 54
           MK      ++LAGG G+RL  +T  V+K  +    K  +I + LS  + +GI  + ++T 
Sbjct: 1   MKKKECLAMLLAGGQGSRLGALTSNVAKPAVSFGGKFRIIDFALSNCVNSGISTVGVLTQ 60

Query: 55  PEDKGYFQRLLGDGSEF-------GIQLE--YAEQP---SPDGLAQAFIIGETFL--NGE 100
                     +G GS +       G+ +   +A Q      +G A A      ++  N  
Sbjct: 61  YRPY-LLHSYIGTGSAWDLDDLGGGVSILPPFATQKGGAWYEGTADAVTQNIDYIEQNDS 119

Query: 101 PSCLVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQV--MDPERFGVVEFDDNFRAISLE 158
              L+L  +  +   +   L          T+    V   +  RFG++  DD+ R     
Sbjct: 120 EYVLILSGDQLYRMDYGEMLACHKEHNADLTIAVMPVPWEEASRFGIITVDDDGRITKFS 179

Query: 159 EKPKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERG--ELEITSINQMYLEAGNLTVELLG 216
           EKP  P SN A  G+Y + ++++  A Q    ++         +    LE G        
Sbjct: 180 EKPTHPDSNLASMGIYVFSTELLLKALQEDALDQQSTHDFGKDVIPRLLEDGKRLYSY-R 238

Query: 217 RGFAWLDTGTHDSLIEASTFVQTVEKRQGF 246
               W D GT  S  E S  +   E     
Sbjct: 239 FEGFWRDVGTISSYHETSMDLLGPEPAFDI 268


>UniRef50_C5ELG1 HAD-superfamily protein n=2 Tax=Clostridiales RepID=C5ELG1_9FIRM
          Length = 261

 Score =  240 bits (613), Expect = 6e-62,   Method: Composition-based stats.
 Identities = 49/239 (20%), Positives = 91/239 (38%), Gaps = 8/239 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ I+LAGG GTRL  +     K +  I  +P + Y    L+ +G+ +I+     +    
Sbjct: 27  MQAILLAGGLGTRLRSVVSDRPKPMALIEGRPFMEYVTRELVRSGMTDIIFAVGYK-GTM 85

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDG  FG    YA + +  G A A      F+  E    VL  + F+   ++   
Sbjct: 86  VEEYFGDGERFGFHASYAYEETLLGTAGAIKNAGRFVTEERFF-VLNADTFYQIDYTRLK 144

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           R   +      +   +V D  R+G    D      +  EK ++ +      G+Y     +
Sbjct: 145 RLQDSLDLDMALVLREVPDVSRYGQAILDGKGFLTAFNEKTEETRMGTINGGIYLMRRSL 204

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           ++   + K S         +   +L  G      +     ++D G  ++  +    V+ 
Sbjct: 205 MDTIPEGKVSLEN-----DMIPKWLREGKGLGGFV-NDGYFIDIGIPEAYRQFQEDVRN 257


>UniRef50_Q01T68 Nucleotidyl transferase n=8 Tax=cellular organisms
           RepID=Q01T68_SOLUE
          Length = 257

 Score =  239 bits (612), Expect = 6e-62,   Method: Composition-based stats.
 Identities = 113/258 (43%), Positives = 154/258 (59%), Gaps = 8/258 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG++LAGG+G+RL P+T+  +K LLPIYD+PMIYYP+  L+ AGI+EILI+T   + G 
Sbjct: 1   MKGVVLAGGTGSRLFPLTKITNKHLLPIYDRPMIYYPIQTLVDAGIQEILIVTGGRNSGD 60

Query: 61  FQRLLGDGSEFGIQ-LEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK 119
           F RLL +G +FG++ + Y  Q    G+A A  + E F +G   C+VLGDNI  G      
Sbjct: 61  FLRLLANGKQFGLKHINYTYQEGEGGIADALALAEHFADGHQICVVLGDNIIEG-NIKAA 119

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSK 179
                A+  GA +   +V D ERFGV E   + R + +EEKP  PKSN+AVTG+Y YD+ 
Sbjct: 120 ADRFRAQPAGAHILLKEVQDAERFGVAEVAGD-RIVGIEEKPNNPKSNYAVTGIYMYDAS 178

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           V +  K + PS RGELEIT +N  Y+  GN++   L     W D GT DSL+ A+  V  
Sbjct: 179 VFQKIKTLVPSGRGELEITDVNNAYIREGNMSFSYL--DGWWTDAGTFDSLLRATNLVAQ 236

Query: 240 VEKRQGFKIACLEEIAWR 257
              +    +A  E  A  
Sbjct: 237 SAAKT---VAVPEFAAEP 251


>UniRef50_A2C5W2 Nucleoside-diphosphate-sugar pyrophosphorylase n=3
           Tax=Cyanobacteria RepID=A2C5W2_PROM3
          Length = 320

 Score =  239 bits (612), Expect = 6e-62,   Method: Composition-based stats.
 Identities = 51/239 (21%), Positives = 90/239 (37%), Gaps = 12/239 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +I+AGG G RL P+T    K +L +  KPM+   L   + +G  E              
Sbjct: 94  VVIMAGGKGMRLRPLTEDCPKPMLLVGGKPMLKILLEQFIASGFEEFYFSVNYLKDKII- 152

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
               +G  +G+ + Y  +  P G A +  +  + +      +V+  ++         LR 
Sbjct: 153 NHFENGERWGVNIRYINEDKPLGTAGSLKLLPSNIK--RPFIVINGDVLTRLNTIQLLRF 210

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
                  AT+   +      FGVV+ D        +EKP+         G+Y  +  ++E
Sbjct: 211 HIDHDALATICVREYEMKVPFGVVQVDGV-ELKGFKEKPR--IRQLVNAGIYVINPALIE 267

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVE 241
             K  +  +  EL +           +  V +      WLD G  +SL EA    + ++
Sbjct: 268 SIKDGQVIDMPELLLNE------SNESRRVTVYPIHEYWLDVGRPESLEEAHATWEELK 320


>UniRef50_A8RPP5 Putative uncharacterized protein n=2 Tax=Clostridium
           RepID=A8RPP5_9CLOT
          Length = 235

 Score =  239 bits (612), Expect = 6e-62,   Method: Composition-based stats.
 Identities = 51/240 (21%), Positives = 93/240 (38%), Gaps = 8/240 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ I+LAGG GTRL  +     K +  I  KP + Y    L+  GI +I+     +    
Sbjct: 1   MQAILLAGGLGTRLRSVVSDRPKPMALIEGKPFMEYVTRELVRHGITDIVFAVGYK-GTM 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDG+ FG    YA + +  G A A      F+  +    VL  + F+   ++  L
Sbjct: 60  VEEHFGDGAAFGFHAGYAYEETLLGTAGAIKNAGRFITEDRFY-VLNADTFYQIDYTRLL 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           R   ++     +   +V D  R+G    D +       EK +  +      G+Y    ++
Sbjct: 119 RQQDSQNLDMALVLRRVPDVSRYGQAILDRDGFLTGFNEKTEDAREGTINGGIYLMKQQL 178

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           ++   + K S         +   +L  G      +     ++D G  ++  +    V+  
Sbjct: 179 LDEIPEGKVSLEN-----DMIPKWLSEGRRLGGFV-NDGYFIDIGIPEAYFQFQEDVRNK 232


>UniRef50_C2KXR6 Glucose-1-phosphate cytidylyltransferase n=1 Tax=Oribacterium sinus
           F0268 RepID=C2KXR6_9FIRM
          Length = 239

 Score =  239 bits (612), Expect = 6e-62,   Method: Composition-based stats.
 Identities = 53/235 (22%), Positives = 86/235 (36%), Gaps = 11/235 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ I+L GG GTRL  +     K +  I  KP + Y L +L   GI E++          
Sbjct: 1   MQAILLCGGMGTRLRSVVSDRPKPMADICGKPFLQYLLEMLREKGITEVIFALGY-MGEM 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +    DGS FG+++ Y+ +  P G   A       +  E   LVL  + +F   +    
Sbjct: 60  IEEYFQDGSAFGLKIAYSYEEDPLGTGGAIRNALPKIMEEE-VLVLNADTYFPMDYQGLY 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQ---PKSNWAVTGLYFYD 177
           R         ++    V D  R+G V  D   R ++  EK +    P +     G+Y   
Sbjct: 119 RFHQENDGDFSLATRAVPDISRYGAVRRDVAGRILAWNEKLEDGGQPLAGEINGGIYVMK 178

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIE 232
             ++    + K S             +L  G      L     ++D G      +
Sbjct: 179 KSLIAEIPEGKQSLEQ-----DCVPKWLSEGKRIFG-LPFDGYFMDIGIPKDYQQ 227


>UniRef50_Q3AQC4 Glucose-1-phosphate thymidylyltransferase n=12 Tax=Chlorobiaceae
           RepID=Q3AQC4_CHLCH
          Length = 349

 Score =  239 bits (611), Expect = 8e-62,   Method: Composition-based stats.
 Identities = 69/290 (23%), Positives = 117/290 (40%), Gaps = 25/290 (8%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK II   G GTRL P T    K LL +  KP+I + +  L+ AGI E ++I        
Sbjct: 25  MKAIIPVAGVGTRLRPHTFSHPKVLLNVAGKPIIGHIMDKLIAAGITEAIVIVGY-LGDM 83

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  L     + I+  +  Q    GL  A  + + ++  +    ++  +  F     P L
Sbjct: 84  IEEWL--LQNYDIKFTFVTQSELLGLGHAISMCKPYIPEDEPLFIILGDTIFDVNLEPVL 141

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFY--DS 178
                ++  +T+   +V+DP RFGV    +N   + L EKP  P SN A+ GLY     +
Sbjct: 142 -----KSTCSTIGVKEVVDPRRFGVAVT-ENGAIVKLVEKPDTPVSNLAIVGLYLLQHSA 195

Query: 179 KVV---EYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAST 235
            +    +Y  +   + +GE ++T   Q  L+ G        +G  W D G  ++L+  + 
Sbjct: 196 ALFKSIDYLIEHNITTKGEYQLTDALQRLLDEGEKFTTFPVQG--WYDCGKPETLLATNE 253

Query: 236 FVQTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLEL 285
            + +          C          ++D      ++ L     G Y    
Sbjct: 254 ILLSDNPPSKTYPGC---------IINDPVFIAESAKLENAIIGPYTTIG 294


>UniRef50_Q31FM5 Nucleotidyl transferase n=1 Tax=Thiomicrospira crunogena XCL-2
           RepID=Q31FM5_THICR
          Length = 361

 Score =  239 bits (611), Expect = 8e-62,   Method: Composition-based stats.
 Identities = 48/244 (19%), Positives = 89/244 (36%), Gaps = 12/244 (4%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +++ GG GTRL P+T  + K +L + DKP++   ++ +   G                +
Sbjct: 122 VVLMLGGLGTRLRPLTESIPKPMLRVGDKPILETIVTHIAEQGFVNFYFCINY-LGEQIR 180

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
              GDGS++GI +EY E+    G A A  +       E   +V+  ++      S  L  
Sbjct: 181 SYFGDGSQWGIHIEYVEEEERRGTAGALSLLPE--KPELPFIVMNGDLLTKVNLSSLLDF 238

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
                  AT    +      +GVVE +     I + EKP      +   G+Y    + +E
Sbjct: 239 HEEHHNIATACVREYAQQVPYGVVEIEGAH-VIQMVEKP--VYRYFVNAGIYALSPEAME 295

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEK 242
              +         ++ ++    L               W+D G      +A    +   +
Sbjct: 296 KVPEQAF-----YDMPTLIDEVLAEKGNVGGFPITE-YWMDIGQMPDFEQAQADYEVHFQ 349

Query: 243 RQGF 246
           ++  
Sbjct: 350 KRNA 353


>UniRef50_A3DMT9 Nucleotidyl transferase n=11 Tax=Thermoprotei RepID=A3DMT9_STAMF
          Length = 426

 Score =  239 bits (610), Expect = 1e-61,   Method: Composition-based stats.
 Identities = 66/294 (22%), Positives = 118/294 (40%), Gaps = 9/294 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAG-IREILIITTPEDKG 59
           MK IILA G G RL PIT    K L+P+  KP++ + L  L     + E++I+ +   K 
Sbjct: 2   MKAIILAAGKGLRLRPITETRPKPLIPVLCKPLLQWQLEALAGINEVDEVVIVVSY-LKE 60

Query: 60  YFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK 119
             ++ +G  +    ++   +Q    G   A +        +   L++  +IF    ++  
Sbjct: 61  QVEQFVGKLN-MPFKITLLDQGEELGTGDAILKAIRKRGIDGKILIIYGDIFLK-DWNEL 118

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSK 179
            + V  R +   + G +V +P  +GV+  D+      + EKP  P SN    GLYF D++
Sbjct: 119 KQLVLTRKDF--IVGVEVDNPSDYGVIVVDEYNSFKGIIEKPAIPPSNLINAGLYFLDAR 176

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
            +     ++ S RGELE T I       G            W+D G    L++A+     
Sbjct: 177 DILKHSDIELSPRGELEFTDILSSMARNGVEIKVYQLSKGKWIDIGKPWHLLDANKMALE 236

Query: 240 VEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRARPRQY 293
               +               ++ +  + ++ + +    Y      +    P  Y
Sbjct: 237 NISTKIIGSIEPGAHVHGRVFVGEGTIVKSGTYIEGPVYIGKNTVI---GPNAY 287


>UniRef50_A7NP68 Nucleotidyl transferase n=2 Tax=Roseiflexus RepID=A7NP68_ROSCS
          Length = 262

 Score =  238 bits (609), Expect = 1e-61,   Method: Composition-based stats.
 Identities = 66/259 (25%), Positives = 106/259 (40%), Gaps = 10/259 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +ILA G+GTRL P+T    K + PI  +P++ + L  L   G+ E  +         
Sbjct: 1   MKALILAAGAGTRLRPLTDTCPKPMAPIAGQPLLAWTLEWLRRYGVTEAALNLHH-LPDV 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  LGDGS FGI+L YA +    G A A      F   + + LV+  ++         +
Sbjct: 60  VRAGLGDGSRFGIRLRYAVEEELRGTAGALHNFPGFF--DQTFLVIYGDLLLDIDLDDLI 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK-QPKSNWAVTGLYFYDSK 179
           R    +    T+   +   P   G+++ D   R     EKP      + A  G+Y  + +
Sbjct: 118 RFHRQQGAIMTLALKRTDTPHSQGMIDIDTTGRVKRFIEKPAVWDGGDTANAGVYVCEPE 177

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           +V +      S+ G      I    L AG        RG+  LD GT  +  +A    + 
Sbjct: 178 IVSWTPPG-FSDFGH----DIIPALLHAGVPVYGRPLRGYL-LDIGTPAAYEQAQQEWRA 231

Query: 240 VEKRQGFKIACLEEIAWRN 258
            ++ +G +    E    R 
Sbjct: 232 RQEARGERGKRQEVSEARG 250


>UniRef50_B4SDB4 Nucleotidyl transferase n=1 Tax=Pelodictyon phaeoclathratiforme
           BU-1 RepID=B4SDB4_PELPB
          Length = 352

 Score =  238 bits (609), Expect = 2e-61,   Method: Composition-based stats.
 Identities = 48/233 (20%), Positives = 87/233 (37%), Gaps = 12/233 (5%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQR 63
           +I+AGG GTRL P T    K +L +  KPM+ + +      G    ++          + 
Sbjct: 127 VIMAGGMGTRLRPHTENCPKPMLSVSGKPMLEHIIERAKQEGFSHFVLAINY-LGHVIEN 185

Query: 64  LLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHV 123
             GDG+   ++++Y ++ SP G A A  +   +        V   ++     +   L   
Sbjct: 186 YFGDGTCLQVRIDYLKEKSPLGTAGALGLLNPW--PTLPFAVTNGDVMTDIHYGELLDFH 243

Query: 124 AARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEY 183
                 AT+          FGVV+ D     I  EEKP     +    G+Y  + + + +
Sbjct: 244 TRHNAAATMAVRVHEWQHPFGVVQTDGID-IIGFEEKPVH--RSHINAGVYVLEPEALCF 300

Query: 184 AKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTF 236
            ++         ++ ++ +        T         WLD G  + L  A+  
Sbjct: 301 LEKNVR-----CDMPALFERLQAKEKRTAAYPIHE-PWLDVGRQEDLTRANMD 347


>UniRef50_B9KYJ6 Glucose-1-phosphate thymidylyltransferase n=5 Tax=cellular
           organisms RepID=B9KYJ6_THERP
          Length = 258

 Score =  238 bits (609), Expect = 2e-61,   Method: Composition-based stats.
 Identities = 110/258 (42%), Positives = 152/258 (58%), Gaps = 9/258 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG++LAGG GTRL+P+T   +K LLP+YD+PMIYYP+  L+ AGI EI+++T     G 
Sbjct: 1   MKGVVLAGGLGTRLYPLTFATNKHLLPVYDQPMIYYPIQTLVKAGIDEIMVVTGGPHAGD 60

Query: 61  FQRLLGDGSEFGIQ-LEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK 119
           F R+L +G   G++ LEYA Q    G+A A  + E F +GE  C++LGDN        P 
Sbjct: 61  FLRVLRNGRHLGVRHLEYAYQEEERGIADALSLCEEFADGEHICVILGDNT-TDADIRPA 119

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNF--RAISLEEKPKQPKSNWAVTGLYFYD 177
           +      T GA +F  +V DP RFG   FD N   R + +EEKPK+PKS +AVTGLY YD
Sbjct: 120 VESF---TGGALIFLARVPDPHRFGCPVFDPNDPTRILRIEEKPKEPKSPYAVTGLYLYD 176

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
           ++V E+ ++++PS RGELEIT +N  YLE G L    +     W D GT +SL  A+ + 
Sbjct: 177 NRVFEFIRELEPSPRGELEITDVNNRYLELGLL--RWVELQGFWSDAGTFESLHRANRYW 234

Query: 238 QTVEKRQGFKIACLEEIA 255
                 +         + 
Sbjct: 235 AERRGYRDPDPILPSALP 252


>UniRef50_D0KYG3 Nucleotidyl transferase n=30 Tax=cellular organisms
           RepID=D0KYG3_HALNC
          Length = 353

 Score =  238 bits (608), Expect = 2e-61,   Method: Composition-based stats.
 Identities = 56/240 (23%), Positives = 96/240 (40%), Gaps = 13/240 (5%)

Query: 5   ILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQRL 64
           ++AGG GTRL P+T    K +L +  KPM+ + L  L+  G     I      +   +  
Sbjct: 125 LMAGGFGTRLRPLTDSCPKPMLKVGGKPMLEHILQDLIDYGFYRFYISVHYLREQVIE-H 183

Query: 65  LGDGSEFGIQLEYAEQPSPDGLAQAFIIG-ETFLNGEPSCLVLGDNIFFGQGFSPKLRHV 123
             DGS FG+ ++Y  + +P G A    +     +      +V+  +I     +   L+  
Sbjct: 184 FKDGSRFGVSIQYIHEDTPLGTAGCLGLLPRDAVQ--RPIIVVNGDIMTRVNYEALLQDH 241

Query: 124 AARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEY 183
              T  ATV   Q      +GV+E  ++ R  ++ EKP Q    +   G+Y    +VV  
Sbjct: 242 DRHTPAATVCTRQYDFQVPYGVIE-HEDQRITNITEKPTQHF--FVSAGIYVLAPQVVHS 298

Query: 184 AKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEKR 243
                      +++  + +  + AG            WLD G  +    A     +V +R
Sbjct: 299 MAADTR-----VDMPDLLKSEITAGRSVRMFPVHE-YWLDIGRMNDFELAQNDAASVLQR 352


>UniRef50_A9W818 Nucleotidyl transferase n=2 Tax=Rhizobiales RepID=A9W818_METEP
          Length = 238

 Score =  238 bits (607), Expect = 2e-61,   Method: Composition-based stats.
 Identities = 60/234 (25%), Positives = 97/234 (41%), Gaps = 12/234 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +I AGG GTRL P T  + K L+PI  KP++   +  L    I E+ I T       
Sbjct: 1   MKAVIQAGGRGTRLMPYTSVLPKPLMPIGAKPVLELLVKWLRRNAIEELYITTGY-LGHL 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDG ++G+ + Y E+  P G   A  + E  L  + + LVL  ++          
Sbjct: 60  IRSFCGDGRQWGLHIVYTEETEPLGTIGALTLLEKHL--DETFLVLNGDVLTDLSLRTFT 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
               A  +  T+      +   FGV+E D +    S  EKP    +N    G+Y  + ++
Sbjct: 118 GIHRAHGQPFTIATACRSNKLDFGVIE-DQDGVVTSFSEKP--VLTNSVSMGIYCMEPEI 174

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
           +++  +  P               L A N+ + +      WLD G  +   +A 
Sbjct: 175 LDHIPRGMP------FGADDLAHCLLAKNVPIHVYKHQGLWLDIGRVEDFHKAQ 222


>UniRef50_A8FIL3 Spore coat polysaccharide biosynthesis protein SpsI n=7
           Tax=cellular organisms RepID=A8FIL3_BACP2
          Length = 246

 Score =  238 bits (607), Expect = 2e-61,   Method: Composition-based stats.
 Identities = 103/249 (41%), Positives = 158/249 (63%), Gaps = 5/249 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+ILAGG G+RL P+T+  +K LLP+   PMIY+ L  L  AGI ++++I+  E    
Sbjct: 1   MKGVILAGGKGSRLAPLTKIFNKHLLPVGPYPMIYWSLFKLKEAGILDVMVISQAEQIPL 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           FQ+LL    E G+ + Y  QP   G++      + F+ GE   L+LGDN+F     SP +
Sbjct: 61  FQKLLEGDQELGMNIVYQVQPEASGISDGLSYAKPFVEGEKFVLMLGDNVFED-SLSPFV 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDD-NFRAISLEEKPKQPKSNWAVTGLYFYDSK 179
                +  GA V   +V DP+RFG+ E D  + R +S+EEKP+ P+S++ VTG+YFYD +
Sbjct: 120 DAFQRQESGAKVLLKEVTDPKRFGIAEIDAVHQRIVSIEEKPEHPRSSYCVTGIYFYDQE 179

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS-TFVQ 238
           V +Y +++ PS+RGELEIT +N +Y+    LT ++L     W+D GTH+SL +AS    +
Sbjct: 180 VFQYIEKISPSDRGELEITDVNNLYISNSQLTYDMLK--GWWIDAGTHESLHQASTKMFE 237

Query: 239 TVEKRQGFK 247
           T++K++G++
Sbjct: 238 TMKKKEGYE 246


>UniRef50_D2LMS4 Nucleotidyl transferase n=3 Tax=Aciduliprofundum boonei T469
           RepID=D2LMS4_9EURY
          Length = 400

 Score =  238 bits (607), Expect = 3e-61,   Method: Composition-based stats.
 Identities = 66/294 (22%), Positives = 127/294 (43%), Gaps = 19/294 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+  ILA G GTR+ P+T    K L+P+ +KP+I + L  L+ AGI +I I+   E +  
Sbjct: 1   MRAFILAAGEGTRMWPLTDTRPKPLIPLANKPIIEHILDALVEAGIEKISILIGYEGRQI 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +R     S  G +++Y  Q    G   A +    +   +   L+L  +++F +     +
Sbjct: 61  AERY--GYSYKGAKIDYVYQNERRGTGDAVLYASKY--NDEKFLILNGDLYFEKSAISDI 116

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                    A +  Y+  + E +G++  D+N     + EK     S     G+Y +  ++
Sbjct: 117 LGHDN----AVLGVYK-DNAESYGLLIGDEN--LEEIREK-VPSSSGLVNAGVYVFHREI 168

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            EY K+V+ S RGE+E T    M+++  +  V+++     WLD G    L++A+      
Sbjct: 169 FEYIKRVELSPRGEIEFTDAINMFVKEHD--VKIVKYNGLWLDIGYPWHLLDATKAYLEK 226

Query: 241 EKRQGFKIACLEEIAWRNGW-LDDEGVKRAASSLAKTGYGQYLLELLRARPRQY 293
             +        E +  +    + +     + + +        + +  +  P  Y
Sbjct: 227 M-KCEIGGEVEENVVLKGKVCIGEGTKIMSGTYIEGPVL---IGKNCKIGPNAY 276


>UniRef50_A8LZU8 Glucose-1-phosphate thymidyltransferase n=15 Tax=Actinomycetales
           RepID=A8LZU8_SALAI
          Length = 353

 Score =  237 bits (606), Expect = 3e-61,   Method: Composition-based stats.
 Identities = 83/278 (29%), Positives = 131/278 (47%), Gaps = 4/278 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++L+GG GTRL P T  + KQL P+ ++P++ + L  +   G+ E+ I+        
Sbjct: 1   MKALVLSGGMGTRLRPFTHSMPKQLFPVANQPVLAHVLGKIRTLGVTEVGIVVGGGGAAQ 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  +GDG+ FG+Q+ Y  Q  P GLA A  +   FL  +   + LGDN+    G    +
Sbjct: 61  VEEAIGDGARFGLQVTYVHQHQPRGLAHAVQVAADFLGTDDFLVYLGDNVLTE-GLVEFV 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                    A +   +V DP  +GVVE D   R   L EKP  P+S+ A+ G+Y +  ++
Sbjct: 120 ARFRDERPAAHLLVQKVSDPRSYGVVELDA-GRVQRLVEKPASPRSDLAIVGVYLFTHEI 178

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
               ++++P  RGELE+T   Q  +++G   VE    G  W D G  D L+E +  + T 
Sbjct: 179 HTAIREIRPGRRGELELTDAVQWLVDSGAR-VEATEYGGNWSDVGQVDDLLECNRHLLTK 237

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
                      E     +G   + G +   S L     
Sbjct: 238 L-DADVAGEVDEVSVVESGVRVEAGARVVRSVLRGPAV 274


>UniRef50_C9LPM2 Nucleotidyl transferase family enzyme n=1 Tax=Dialister invisus DSM
           15470 RepID=C9LPM2_9FIRM
          Length = 232

 Score =  237 bits (605), Expect = 4e-61,   Method: Composition-based stats.
 Identities = 51/242 (21%), Positives = 91/242 (37%), Gaps = 13/242 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK  +LA G GTRL P+T  V K L+PI  +P++ + + +     I EILI T       
Sbjct: 1   MKAFLLAAGLGTRLRPLTWTVPKCLVPIQGRPLLAWWMDLFEQHRISEILINTNYLPDPV 60

Query: 61  ---FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFS 117
               +    + +   ++L  + +    G     +I   F+  E    +   +       S
Sbjct: 61  RKFIKEY--NQTRGKVKLVESYEKELLGSGGTVLINRNFVENEEDFFICYADNLTNADLS 118

Query: 118 PKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYD 177
             +          T+  +   +P   G+  ++   +     EKPK PKS+ A  G+Y  +
Sbjct: 119 SMMDFHKKNHALLTMGLFHTNNPTGCGIAVYNKEGKITEFVEKPKYPKSDLANAGIYVVN 178

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
            K+ +Y       + G      +    +           + +  LD GT  +  EA    
Sbjct: 179 KKIYDYIPNKSFVDFG----GDVLPELV---GKMYGYPIKEYL-LDVGTWPNYEEAQEKW 230

Query: 238 QT 239
           + 
Sbjct: 231 RK 232


>UniRef50_Q0G1T6 Nucleotidyl transferase n=1 Tax=Fulvimarina pelagi HTCC2506
           RepID=Q0G1T6_9RHIZ
          Length = 344

 Score =  237 bits (605), Expect = 4e-61,   Method: Composition-based stats.
 Identities = 55/237 (23%), Positives = 92/237 (38%), Gaps = 12/237 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            I++AGG G RL P+T  + K +LP+  +P++   L      G R   I          +
Sbjct: 119 VILMAGGLGKRLRPLTETMPKPMLPVGGRPLLEIILRNFTDQGFRNFTICLNY-MANVVR 177

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
              GDGS F   + Y ++    G A A  +           +++  ++     F   +R 
Sbjct: 178 DYFGDGSAFDSSITYVQEEEALGTAGALTLLPE--RPSRPFIIMNGDLLTTLHFESVIRF 235

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
                  AT+   + +    +GVV  D + R +S+EEKP    S +   G+Y      +E
Sbjct: 236 HDEHLADATLCAREHLVQIPYGVVRSD-DARLLSIEEKPT--ISQYVNAGIYVLSPNSLE 292

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
                    R   ++T +    LE     V    R   W+D G    L +A +  + 
Sbjct: 293 LLA-----YREHADMTQLFDRILERNMKAVVFPMRE-YWIDVGQIGDLQKARSDFRK 343


>UniRef50_Q26CD7 Putative nucleoside diphosphate sugar pyrophosphorylase n=1
           Tax=Flavobacteria bacterium BBFL7 RepID=Q26CD7_9BACT
          Length = 347

 Score =  237 bits (605), Expect = 4e-61,   Method: Composition-based stats.
 Identities = 57/239 (23%), Positives = 101/239 (42%), Gaps = 12/239 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +I+AGG G RL P+T  + K +LP+ DKP+I + +  L+  GI++I I          +
Sbjct: 121 CMIMAGGRGKRLSPLTDSIPKPMLPLGDKPIIEHNIDRLISFGIQKIYISVKY-LGEQLE 179

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
              GDGS  GIQ+EY  +  P G A A  + + F       L++  ++F    F      
Sbjct: 180 AYFGDGSSKGIQIEYIWEDEPLGTAGALKLVDKF--NTDYVLLMNSDLFTSVNFEEMYLQ 237

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
           +        V   +      + V E D N +  + +EKP     +    G+Y     +++
Sbjct: 238 LLQENADMVVASTEYKVDVPYAVFETDGN-KVKAFKEKPSYIYQS--NAGIYILKRSLID 294

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVE 241
              + +       +IT + +  ++ G   V        W+D G      +A  F++  +
Sbjct: 295 QMTKNEY-----CDITDVMEKLVQDGGKLVYDPIL-GFWIDIGKPSDYKQAQEFIKHFK 347


>UniRef50_A6C2H5 Nucleoside-diphosphate-sugar pyrophosphorylase n=1 Tax=Planctomyces
           maris DSM 8797 RepID=A6C2H5_9PLAN
          Length = 377

 Score =  237 bits (605), Expect = 4e-61,   Method: Composition-based stats.
 Identities = 61/253 (24%), Positives = 103/253 (40%), Gaps = 13/253 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +I+AGG G RL P+T  + K L+ +   P+I   +  +  AG+  I +          +
Sbjct: 127 ALIMAGGEGRRLLPLTENLPKPLVEVGGMPLIERQVRRIAHAGVNRIYVAVNY-LAEMIE 185

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
             LGDGS FG+++ Y  +P   G A +  +    L+G    L++  ++F    F   L  
Sbjct: 186 SHLGDGSRFGVEIHYLREPKKLGTAGSLSLITEKLDG--PLLLMNGDVFTSINFQYLLDF 243

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
            +      TV          +GV++ +  F    LEEKP Q        G+Y    + V 
Sbjct: 244 HSKHQPLITVAAIDYHVEIPYGVIKTEGPFAIC-LEEKPSQ--QFLCNAGIYALSPEAVS 300

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEK 242
                +        +T + +  L   +           W D GTH  L +A + ++ V +
Sbjct: 301 RVPPNQI-----FNMTDLIESGLSQKDGVAVFPVHE-YWSDIGTHAELDKARSELKIVRE 354

Query: 243 RQGFKIACLEEIA 255
             G  +   +EIA
Sbjct: 355 TLG-DLEESDEIA 366


>UniRef50_C7P380 Nucleotidyl transferase n=20 Tax=Halobacteriaceae
           RepID=C7P380_HALMD
          Length = 253

 Score =  236 bits (604), Expect = 6e-61,   Method: Composition-based stats.
 Identities = 64/256 (25%), Positives = 106/256 (41%), Gaps = 12/256 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++LA G GTRL P+T    K ++ +  KP++ +    L+  G  E+L++   + +  
Sbjct: 1   MKAVVLAAGEGTRLRPLTEDKPKGMVEVAGKPILTHCFEQLIELGADELLVVVGYKKQVI 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                 D  E G+ + YA Q    GLA A +  E  +  +   L+LGDNIF        +
Sbjct: 61  I-NHFEDEFE-GVPITYAHQRDQKGLAHALLTVEEHI-DDDFMLMLGDNIF-QANLRDVI 116

Query: 121 RHVAARTEGATVFGYQV--MDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDS 178
                    A     +V   +  R+GV + +       + EKP  P SN  +TG Y +  
Sbjct: 117 NRQREERADAAFLVEEVPWEEASRYGVCDTNKYGEIEEVVEKPDDPPSNLVMTGFYTFTP 176

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
            +      V+PS R E EI+    + L +G  T++ +       D G  +          
Sbjct: 177 AIFHACHLVQPSNRDEYEISDAIDLLLHSGR-TIDAIRMDGWRTDIGYPED-----RDAA 230

Query: 239 TVEKRQGFKIACLEEI 254
                 G ++   E +
Sbjct: 231 EKRLTGGAEVDDDEAV 246


>UniRef50_B0VGT1 Putative Mannose-1-phosphate guanylyltransferase n=1 Tax=Candidatus
           Cloacamonas acidaminovorans RepID=B0VGT1_9BACT
          Length = 231

 Score =  235 bits (601), Expect = 1e-60,   Method: Composition-based stats.
 Identities = 58/242 (23%), Positives = 102/242 (42%), Gaps = 11/242 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +IL+GG G+RL P T  + K LLPI +K ++   +  L   G   I + T  + + Y
Sbjct: 1   MKAVILSGGLGSRLKPFTEVIPKPLLPIGEKAVLEIQIEHLKNNGFDHIFLATNYKSE-Y 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   G+GS++G++L  +++  P G A    + +  LN EP  LV+  +I     +    
Sbjct: 60  IENFFGNGSKYGVKLSISKEEKPLGTAGPVKLLQNQLNNEP-FLVMNGDILTLLPYRKLY 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
               ++    T+    +  P +FG +  + +F    +EEKP        + G+Y +  ++
Sbjct: 119 EFACSKETLLTIATKDIYTPFQFGNIHTEGDF-VTGIEEKPN--IKTTILAGIYIFKPEI 175

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           +            +L I       LE          +   WLD G      +A    +  
Sbjct: 176 LNLIPDNTMYGMDKLII-----DMLERRLPISHYPIQE-YWLDIGQVGDYEKAQEIYKEH 229

Query: 241 EK 242
            K
Sbjct: 230 FK 231


>UniRef50_Q7U909 Putative sugar-phosphate nucleotide transferase n=1
           Tax=Synechococcus sp. WH 8102 RepID=Q7U909_SYNPX
          Length = 352

 Score =  235 bits (601), Expect = 1e-60,   Method: Composition-based stats.
 Identities = 56/233 (24%), Positives = 90/233 (38%), Gaps = 11/233 (4%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQR 63
           +I+AGG G RL P+T    K +LP++ KPM+ + L  L   G + ++I            
Sbjct: 130 VIMAGGKGKRLMPLTANTPKPMLPVHGKPMLEHILDRLREDGFKNVIISVNY-LSERITS 188

Query: 64  LLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHV 123
              DGS+F + + Y  +  P G A A   G      E   +V   +I  G  +S  L + 
Sbjct: 189 YFQDGSKFDMNISYLYEDKPLGTAGALS-GLDSKTRENPVIVTNADILSGISYSDLLIYF 247

Query: 124 AARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEY 183
              T    +          FGVV+ + +    ++ EKP          GLY  D+K+++ 
Sbjct: 248 RRNTSNGLMAVRTQEWQNPFGVVQSNGSH-ITNIIEKPTHYYQ--VNAGLYVLDNKLLDL 304

Query: 184 AKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTF 236
                       ++  + +M LE              WLD G       A+  
Sbjct: 305 LTPNSY-----CDMPDLFRMGLEINLNLQVYPLHE-QWLDIGRPKDYDIANKE 351


>UniRef50_B0THI4 D,d-heptose 1,7-bisphosphate phosphatase subfamily, putative n=1
           Tax=Heliobacterium modesticaldum Ice1 RepID=B0THI4_HELMI
          Length = 397

 Score =  235 bits (600), Expect = 2e-60,   Method: Composition-based stats.
 Identities = 56/293 (19%), Positives = 108/293 (36%), Gaps = 15/293 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +IL GG G RL  +T+ + K ++ I  KP +   ++ L   GI+ IL++        
Sbjct: 1   MQAVILVGGLGARLGTLTKKMPKPMMDIGGKPFLELIINNLKRFGIKNILLLVGYRCHDI 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                 DGS + + + Y+ +  P G   A ++    L  E   L+L  + FF       L
Sbjct: 61  I-DYFQDGSRWNVIIRYSIEREPAGTGGALLLASDKLEDE--FLLLNGDTFFDFNILDLL 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
             V        V        ER+G +  ++  R  S  EK    KS    +G+Y     +
Sbjct: 118 VRVPHGKWEFKVALTPSKSSERYGSIIINNENRVTSFVEKRTHLKSALINSGIYHVRKSI 177

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           ++Y   +  S         +    +    +   +      ++D G    L      +   
Sbjct: 178 LKYIDSIPCSLENH-----VLPKIVSNEQMYGYIY--NGYFVDIGIPCDLERGRMDLPD- 229

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEG----VKRAASSLAKTGYGQYLLELLRAR 289
            KR    +     I +  G++  +     ++ A  ++       Y + ++  +
Sbjct: 230 RKRPAAFLDRDGVINYDKGYVHKKEDFNWMQGAIEAIKYLNDIGYYVIVITNQ 282


>UniRef50_D1PXL9 Mannose-1-phosphate guanyltransferase n=2 Tax=Bacteroidales
           RepID=D1PXL9_9BACT
          Length = 416

 Score =  234 bits (599), Expect = 2e-60,   Method: Composition-based stats.
 Identities = 51/305 (16%), Positives = 104/305 (34%), Gaps = 23/305 (7%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +I+AGG GTR+  +   + K ++P+  KP+I + + +    G  E + +        
Sbjct: 1   MKVVIIAGGQGTRIASLNSEIPKAMIPVCGKPVIEHQVEMAKRYGFTEFIFLIGY-LGEQ 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   G+GS + + ++Y  + +P G A A       L+ +    V   +           
Sbjct: 60  VESYFGNGSHWDVHIDYYHETTPLGTAGAIAEVRDKLSDD--FFVFYGDTVMDVDMRRME 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP---KQPKSNWAVTGLYFYD 177
                    AT+F +    P    +V  D + R +S+  KP        N     L+ + 
Sbjct: 118 TFHKEHRADATLFVHPNDHPYDSDIVILDKDHRVMSIATKPHADDFVSHNIVNAALFIFS 177

Query: 178 SKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
             +V+  ++   +        ++    ++ G      L   +   D GT +    A    
Sbjct: 178 KNIVDCIEKGTKT----HIEKNVLPECIKRGMKLYGYLSSEYV-KDMGTPERYEAACKAW 232

Query: 238 QTV--------EKRQGFKIACLEEIAWRNGWLDDEG----VKRAASSLAKTGYGQYLLEL 285
                       +R+   +     I    G +        +     +L       YL  +
Sbjct: 233 ACGQVASMNFSNQRKAIFLDRDGVINEDTGLVYKPSHLVLIDGVEEALKYIHQKGYLAVV 292

Query: 286 LRARP 290
           +  + 
Sbjct: 293 VTNQS 297


>UniRef50_A7GGU6 Nucleotidyl transferase family protein n=4 Tax=Clostridium
           botulinum RepID=A7GGU6_CLOBL
          Length = 358

 Score =  234 bits (599), Expect = 2e-60,   Method: Composition-based stats.
 Identities = 51/239 (21%), Positives = 103/239 (43%), Gaps = 12/239 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            II+AGG GTRL  +T+ + K +L I + P++ + ++     G  +  I    + +   +
Sbjct: 123 VIIMAGGLGTRLKDLTKEIPKPMLRIGNDPILQHIINNFKQYGYNKFFISVNYKAE-IIE 181

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
               DG  +G+++EY ++    G A    + E+F+N      V+  +IF        + +
Sbjct: 182 NYFQDGYIYGVKIEYIKEQKRMGTAGGIKLAESFVNK--PFFVINGDIFTNLNLENMMTY 239

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
               +   TV   +      +GVV+ ++N   I ++EKP          G+Y  + KV+ 
Sbjct: 240 HIDNSFDITVGTRKHSFQIPYGVVKTEEN-SIIGMKEKPNME--YLINAGVYCLNPKVIN 296

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVE 241
              Q +       EIT +  + ++ G        +   W+D G  +   + +  +  ++
Sbjct: 297 LIPQDEY-----FEITDLIGICIKNGLKVGCYEIKE-YWMDIGRIEDYNQVNEDIYNLD 349


>UniRef50_A8MDH4 Nucleotidyl transferase n=6 Tax=Thermoproteaceae RepID=A8MDH4_CALMQ
          Length = 237

 Score =  234 bits (599), Expect = 2e-60,   Method: Composition-based stats.
 Identities = 49/237 (20%), Positives = 102/237 (43%), Gaps = 14/237 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M  +ILAGG G RL P+T    K L+ +  +P++ + +  L   G+ +I++         
Sbjct: 3   MFAVILAGGFGKRLRPLTDDRPKPLVEVAGRPILAWQIDWLREQGVTDIILAVGYLGGKI 62

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F   +GDGS+FG+++ Y+ +  P G   A      ++N +   +V   ++         +
Sbjct: 63  F-DYIGDGSQFGVRVYYSVEREPLGTGGAVRNALKYINDDGFIVV-NGDVITNLRIGKLM 120

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
             +  R     +    +     +G+V+ D++   ++ +EKP+ P       G+Y   + +
Sbjct: 121 DSL-QRGVIGAIALTPLK--SPYGIVQVDEDGFILNFQEKPQLP--YLINAGVYALRTSI 175

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
            +Y  +     +G++E+ +  +  L      + +      W    T   L EA   +
Sbjct: 176 RDYLPE-----KGDIEVYTFPR--LAKDKKLIGITYNDVYWKSIDTLKDLEEADKAI 225


>UniRef50_Q036S8 Glucose-1-phosphate adenylyltransferase n=9 Tax=Lactobacillus
           RepID=GLGC_LACC3
          Length = 380

 Score =  234 bits (599), Expect = 2e-60,   Method: Composition-based stats.
 Identities = 64/265 (24%), Positives = 110/265 (41%), Gaps = 21/265 (7%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDK-PMIYYPLSVLMLAGIREILIITTPEDKG 59
           M G+ILAGG GTRL  +T+  +K  +P   +  +I + LS L  +G+    +IT  +   
Sbjct: 5   MLGMILAGGQGTRLGKLTKTTAKPSVPFGGRYRIIDFTLSNLANSGVNTAGVITQYQPLE 64

Query: 60  YFQRLLGDGSEFGIQ-----LEYAE-------QPSPDGLAQAFIIGETFLN--GEPSCLV 105
              R + +G+ +G+      +   +       +   +G A A      +++       L+
Sbjct: 65  L-NRHIQNGASWGLNERGAGVTILQPYASSEGEKFFEGTAHAIYQNIAYIDSYNPQYLLI 123

Query: 106 LGDNIFFGQGFSPKLRHVAARTEGATVFGYQVM--DPERFGVVEFDDNFRAISLEEKPKQ 163
           L  +  +   +   L +  A+    TV    V   + +RFG++  DD  R I  EEKP +
Sbjct: 124 LSGDHIYKMDYQAMLDYHKAKKASLTVAVMPVEKEEAKRFGIMNTDDTDRIIEFEEKPAK 183

Query: 164 PKSNWAVTGLYFYD-SKVVEYAKQVKPSERG-ELEITSINQMYLEAGNLTVELLGRGFAW 221
           PKSN A  G+Y ++   + +Y  +   ++   E     +   YL     +         W
Sbjct: 184 PKSNLASMGIYIFNWPTLKQYLTESYATDGAMEDFGHDVIPAYLTHNEASYAY-AFRGYW 242

Query: 222 LDTGTHDSLIEASTFVQTVEKRQGF 246
            D GT  SL EA+            
Sbjct: 243 KDVGTIQSLWEANMEFLNPNNPLNI 267


>UniRef50_Q0W734 Nucleotidyltransferase family protein n=2 Tax=Euryarchaeota
           RepID=Q0W734_UNCMA
          Length = 231

 Score =  234 bits (598), Expect = 3e-60,   Method: Composition-based stats.
 Identities = 62/241 (25%), Positives = 103/241 (42%), Gaps = 17/241 (7%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK  IL GG G RL PIT  + K ++P+  KP++ Y + +L   G+R+I+ +     +  
Sbjct: 1   MKAFILCGGRGERLKPITDKIPKPMVPVAGKPILEYQVDLLKKHGVRDIVFLVGWYGEA- 59

Query: 61  FQRLLGDGSEFGIQLEYAEQP--SPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSP 118
            +   GDGS+FGI+ EY+ +   +  G A      +  ++G    +V+  +I      S 
Sbjct: 60  IEAYFGDGSKFGIRAEYSYEDPNNRLGTAGPIKAAKDKVDGA--IIVMNGDIISNTNISE 117

Query: 119 KLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDS 178
            +     +    T+    +  P  FG+++ + +       EKP  P       GLY  ++
Sbjct: 118 IVAFHTKKKCLGTI--NMINMPSPFGIIDLNGDH-ITQFREKPVLPFK--MNAGLYVIEA 172

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
            VV+    V          T +       G L       G  W D GTH  L + +  VQ
Sbjct: 173 DVVDMMPAVG------SIETDVFPKIAAEGKL-CGYDSTGIYWSDVGTHKDLEKVTKDVQ 225

Query: 239 T 239
           +
Sbjct: 226 S 226


>UniRef50_Q28JE9 Nucleotidyl transferase n=1 Tax=Jannaschia sp. CCS1
           RepID=Q28JE9_JANSC
          Length = 240

 Score =  234 bits (597), Expect = 3e-60,   Method: Composition-based stats.
 Identities = 57/236 (24%), Positives = 94/236 (39%), Gaps = 8/236 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +K ++LAGG GTRL P+T  + K L+P+  KP++ Y L  L  A IR+ L+ T  +    
Sbjct: 4   VKALLLAGGLGTRLRPLTDTLPKCLIPVAGKPILDYWLDALDAADIRQALLNTHHKRDQV 63

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
              L    S   + +  A +P   G A        + +     +V+  +          +
Sbjct: 64  KIWLETANSSRNVAIAEAYEPELLGSAGTVTANRDWADDASEVVVIYADNLSDIDLGALV 123

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                 ++  T+  +    P + G+   DD+ R  +  EKP QP+S+ A  GLY  D+  
Sbjct: 124 AFHRTHSDPMTMMLFHTPYPSKCGIATLDDDARVTAFVEKPDQPESDLANAGLYVLDASA 183

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTF 236
                 +   + G   I +                       D GTH+SL +A   
Sbjct: 184 WREIADMGAFDFGFDVIPAFVGRM--------RGYAHPGYHRDIGTHESLAQAEAD 231


>UniRef50_B8D6C9 Glucose-1-phosphate thymidylyltransferase n=1 Tax=Desulfurococcus
           kamchatkensis 1221n RepID=B8D6C9_DESK1
          Length = 427

 Score =  234 bits (597), Expect = 4e-60,   Method: Composition-based stats.
 Identities = 71/294 (24%), Positives = 121/294 (41%), Gaps = 13/294 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAG-IREILIITTPEDKG 59
           MK +ILA G+G RL PIT    K L+PI  KP++ + L  L     I E++I+T      
Sbjct: 1   MKAVILAAGNGIRLKPITETRPKPLIPILCKPLLDWHLDRLAAVSFIDEVVIVTGY-MGD 59

Query: 60  YFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPK 119
             +  +        ++ + EQ  P G   A + G   +  +   L++  +IF      P+
Sbjct: 60  IIRAHV-MSRRLPFKVRFVEQGEPRGTGDAVVKGIEGMGSDDDVLIIYSDIFTPVNIIPE 118

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSK 179
           +    A   G  + G +V +P  +GV+  + N+    + EKP  P S     G+Y   ++
Sbjct: 119 I----AGESGNIIVGSEVDNPSDYGVLINEGNYF-KGVVEKPMNPPSRLVNAGIYKLRTR 173

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
            +     +KPS RGELE T +       G            W+D G    +IEA+    T
Sbjct: 174 DILDNSDIKPSPRGELEFTDVLNNMSRRGVKIRIYKLPRALWIDIGKPWHVIEANKMALT 233

Query: 240 VEKRQGFKIACLEEIAWRN-GWLDDEGVKRAASSLAKTGYGQYLLELLRARPRQ 292
           + K+   K   +E        ++ +  +    + +       Y+   +   P  
Sbjct: 234 MVKK-EIKGRVIEPSHIIGEVYIGENSLVNPFTMIEGPA---YIDREVEIGPNA 283


>UniRef50_A4BEN1 Nucleoside-diphosphate-sugar pyrophosphorylase n=3
           Tax=Proteobacteria RepID=A4BEN1_9GAMM
          Length = 359

 Score =  233 bits (596), Expect = 4e-60,   Method: Composition-based stats.
 Identities = 50/240 (20%), Positives = 88/240 (36%), Gaps = 11/240 (4%)

Query: 5   ILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQRL 64
           ++AGG G RL P+T    K +L + DKP++   L   + AG     I T        +  
Sbjct: 124 LMAGGFGKRLRPLTNNCPKPMLKVGDKPILETILEQFIDAGFHNFFISTHY-LNEQIEAY 182

Query: 65  LGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHVA 124
            GDG+ +G+ + Y  + +P G A A  +        P  L++  ++     F   L +  
Sbjct: 183 FGDGANYGVSISYINEQTPLGTAGAIGLLPESAKQLP-FLMMNGDLLTRVNFDELLEYHM 241

Query: 125 ARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEYA 184
                 +V   +      FGVV+   +     + EKP Q  + +   G+Y          
Sbjct: 242 REGSDVSVAVREYQMQVPFGVVQHQGS-VISDIVEKPVQ--NYFINAGIYCISPS----- 293

Query: 185 KQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEKRQ 244
                     L++  + +  ++ G            WLD G      +A     +   R+
Sbjct: 294 AAFAVDGINVLDMPDLIESRIKLGRKVSMFPIHE-YWLDIGQLPDFEQAQIDYSSRFSRR 352


>UniRef50_C5A4I2 Sugar-phosphate nucleotydyltransferase n=9 Tax=Thermococcaceae
           RepID=C5A4I2_THEGJ
          Length = 420

 Score =  233 bits (595), Expect = 5e-60,   Method: Composition-based stats.
 Identities = 68/280 (24%), Positives = 116/280 (41%), Gaps = 11/280 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++LA G G RL P+T    K +L + ++P+I Y +  L    + E +I+   E +  
Sbjct: 1   MKAVVLAAGKGERLKPLTDDRPKVILKVANRPIIEYVMENLYPF-VDEFIIVVRYEKEKI 59

Query: 61  FQRLLGDGSEF-GIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQG-FSP 118
            + L   G EF G  + Y EQ   +G A+A       +  E   +V   +I+F       
Sbjct: 60  IETL---GDEFGGKPVTYVEQRPGEGTAKAVESAREHVGDEE-FIVANGDIYFEVEAIKE 115

Query: 119 KLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDS 178
            +         A +      D   FG VE  +  R + + EKP +    +A  G+Y +  
Sbjct: 116 LVSAFRREKADAALVLKHFEDLSHFGKVEVKE-GRVVGILEKPGKVPG-YANLGIYLFRP 173

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
            V E+  +   SERGE EIT    + ++AG      +     W D G   +L+E + ++ 
Sbjct: 174 DVFEFIGETPLSERGEYEITDTINLMIKAGKKVAYAVYSD-YWNDIGRPWNLLELNEYLL 232

Query: 239 TVEKRQGFKIACLEEIAWRNGW-LDDEGVKRAASSLAKTG 277
             + R   +    E         + +  V R+ + +    
Sbjct: 233 KTKLRHEIRGTVEEGATIIPPVEIGEGTVVRSGAYIIGPV 272


>UniRef50_A1WSE0 Nucleotidyl transferase n=1 Tax=Verminephrobacter eiseniae EF01-2
           RepID=A1WSE0_VEREI
          Length = 351

 Score =  233 bits (595), Expect = 6e-60,   Method: Composition-based stats.
 Identities = 52/235 (22%), Positives = 89/235 (37%), Gaps = 12/235 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +++AGG G RL PIT+ + K ++P+  KP++ + L  L   G RE             +
Sbjct: 125 VVVMAGGKGQRLLPITQDLPKPMVPVGGKPILEWILLRLRHYGFREFSFAINY-LGHMIE 183

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
              GDGS F  ++ Y  +    G A A  +           +V   +I  G  F   +  
Sbjct: 184 DYFGDGSAFDCRIRYIREKEFLGTAGALSLLPP--GDAHPLVVTNGDILSGIDFGHLVDF 241

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
            AA    ATV          +GV++   +     + EKP     +    G+Y    +V+ 
Sbjct: 242 HAAGGRSATVCARAHRVEVPYGVLQM-SDGCLQGIVEKPVHD--HLISAGIYVLSPQVLP 298

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
              Q +      L++  +    ++  +     +     W+D G HD L       
Sbjct: 299 RIPQGQA-----LDMPELLLSLIDEHHKIGVFVLED-EWVDVGRHDDLERVRRSF 347


>UniRef50_A8MC98 Nucleotidyl transferase n=1 Tax=Caldivirga maquilingensis IC-167
           RepID=A8MC98_CALMQ
          Length = 364

 Score =  233 bits (595), Expect = 7e-60,   Method: Composition-based stats.
 Identities = 55/277 (19%), Positives = 101/277 (36%), Gaps = 8/277 (2%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +  IILAGG  TRL P+T    K LLPI +K +I + L  +      ++ +      +  
Sbjct: 2   VDVIILAGGYATRLRPLTFTKPKPLLPILNKAVIDWILESVTKVKPSDVFLSVRYMSELI 61

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            + +    +     +   ++  P G         +    +   +V   +IF        +
Sbjct: 62  EKHVNHRWASLRDIVNIIKEDKPLGDGGPVSYIASMRELDDIVVVFNGDIFTKIDLEDAI 121

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
               ++   AT+   QV D  ++GVV    +       EKP+  +  SN    G+Y +  
Sbjct: 122 NEHVSKGALATICLTQVNDVSQYGVVTLGRDNLVTGFVEKPEPGKAPSNLINAGVYIFSK 181

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
             ++Y    KP   G+L I  I    ++   +   +L     W D GT  S ++A+    
Sbjct: 182 DALKYFP--KPGTFGKLAI-DILPKMIKDHKVYGYILK--GYWYDIGTITSYLDANFRAL 236

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAK 275
               R          I     ++ +       + +  
Sbjct: 237 DEYCRDCPAPNNEALIKPPA-FIGENVTIEPGAEVGP 272


>UniRef50_B8IAD4 Nucleotidyl transferase n=1 Tax=Methylobacterium nodulans ORS 2060
           RepID=B8IAD4_METNO
          Length = 238

 Score =  233 bits (594), Expect = 7e-60,   Method: Composition-based stats.
 Identities = 56/239 (23%), Positives = 91/239 (38%), Gaps = 10/239 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK I+LAGG GTRL P +  + K L+PI + P++   L  +   GI E+++         
Sbjct: 1   MKAIVLAGGKGTRLMPYSALIPKPLMPIGEMPILELLLRQMKHHGISEVILAVNH-LHHL 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GDGS  G+++ Y+ +    G +         L+ +   LV   ++     F   +
Sbjct: 60  IRSFFGDGSSLGLKITYSVEDKALGTSGPITANLDALSDD--FLVSNGDLLTNLDFGAMM 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           R   AR   AT+          +G +  D +       EKP    S  A  GLY    K 
Sbjct: 118 RQHIARQVAATIATQSRAMQADYGALTVDKDNLIREYREKP--IFSFEASMGLYVLSKKA 175

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           V     V        ++  + +  +EA    +        W+D G  +    A      
Sbjct: 176 VRPHLPVNTF----FDMPDLIKSLIEADQPVLSY-NETCNWIDIGKPNDYGRAQERFAA 229


>UniRef50_C4PX01 Gdp-mannose pyrophosphorylase b, isoform 2 n=1 Tax=Schistosoma
           mansoni RepID=C4PX01_SCHMA
          Length = 413

 Score =  233 bits (594), Expect = 8e-60,   Method: Composition-based stats.
 Identities = 54/282 (19%), Positives = 99/282 (35%), Gaps = 15/282 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +IL GG GTRL P+T  + K L+   +KPM+ + +  L+   I EI++    E +  
Sbjct: 54  MKALILIGGYGTRLRPLTLSIPKPLVEFANKPMLLHQIKALLEVDITEIILAINREAEVL 113

Query: 61  FQRLLGDGSEFGI---QLEYAEQPSPDGL-AQAFIIGETFLNGEPSCLVLGDNIFFGQGF 116
              +     + G+    + +   P               FL GE    VL  +I     F
Sbjct: 114 ESSIRESCDKVGVNHCNVFFV--PYILVTVGGPLAQAAPFLTGERFF-VLNSDIICNYPF 170

Query: 117 SPKLRHVAARTEGATVFGYQVMDPERFG-VVEFDDNFRAISLEEKPKQPKSNWAVTGLYF 175
              L    +  +  T+   +V +P ++G VV  D         EKP +  +N    GLY 
Sbjct: 171 KRMLEFHLSHGKEGTMAVTKVEEPSKYGAVVHNDQTGLVKRFVEKPSEYVANRINAGLYI 230

Query: 176 YDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAST 235
           ++  +++  +    S       T++    +    L    +     W+D G     +    
Sbjct: 231 FEPTILKRIEAKPMSIE-----TAVFPAMVRDSEL--YCIEFSGFWMDIGQPADYLTGMR 283

Query: 236 FVQTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTG 277
                       +  ++     N  + +         +    
Sbjct: 284 LYLGHLYECKSPLLTVDPNLIGNVLVHETAKLGHGCRIGPNV 325


>UniRef50_C7NV90 Nucleotidyl transferase n=1 Tax=Halorhabdus utahensis DSM 12940
           RepID=C7NV90_HALUD
          Length = 397

 Score =  233 bits (594), Expect = 9e-60,   Method: Composition-based stats.
 Identities = 60/277 (21%), Positives = 109/277 (39%), Gaps = 16/277 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            I+LA G GTRL P+T    K +LP  + P++ Y L  L+ AG+ E++++   E +   Q
Sbjct: 6   AIVLAAGEGTRLRPLTHNRPKPMLPAGNTPILEYVLDALVEAGVEELVLVVGYE-RDRVQ 64

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGF-SPKLR 121
             +G     G  + Y +Q    G   A +  +  + G    LV+  +             
Sbjct: 65  NHVGPTYR-GRPVTYVDQTKQLGTGHALLQAQAAVEGS--FLVVNGDTLIDPTIVEDVTD 121

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVV 181
                   AT+      DP  +G V   ++    +L EKP   +  +   G+Y ++  + 
Sbjct: 122 QFEESEPRATLAVLDGPDPTDYGAVLV-EDGLVTNLVEKPDAGEYRYINAGVYAFEPSIF 180

Query: 182 EYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVE 241
           E  ++  P E GEL +T      ++    +V  +     W+D      L+E +  V    
Sbjct: 181 EMIERT-PREAGELALTDTLARLIDD--RSVGAVETDGTWVDATYPWDLLELARTVLA-- 235

Query: 242 KRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
                ++   E  +    W+D       A+++     
Sbjct: 236 ---NGRLDPPE--SRDQVWIDASASVHEAATIQPPAV 267


>UniRef50_B5EDT7 Nucleotidyl transferase n=5 Tax=Bacteria RepID=B5EDT7_GEOBB
          Length = 240

 Score =  232 bits (593), Expect = 1e-59,   Method: Composition-based stats.
 Identities = 53/244 (21%), Positives = 96/244 (39%), Gaps = 12/244 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +ILAGG GTRL P T  + K L+PI + P++   +  L+  G   I +    + K  
Sbjct: 1   MRAVILAGGRGTRLRPYTVVLPKPLMPIGEYPILEVIVRQLVHCGFTHITMAVNHQAK-I 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            Q   G+G  +GI ++Y+ +  P        + +       + LV+  +I     F    
Sbjct: 60  IQAFFGNGERWGITIDYSLETKPLSTMGPLRLIDDL---PENFLVMNGDILTDLNFREFH 116

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
            +        T+  YQ +    +GV++ +   +    EEKP+         G+Y  +   
Sbjct: 117 DYHVRVKNNFTIAAYQRVLKSEYGVLKINRQKKLCGFEEKPEYLLD--VSMGVYMVNRDT 174

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           + +     P     L +       L  G     +      WLD G  D  ++A     ++
Sbjct: 175 MRHIPADTPYGFDHLML-----DLLAEG-HPASVKIHKGFWLDIGRPDDYMQAIEEFDSL 228

Query: 241 EKRQ 244
           + + 
Sbjct: 229 KGKF 232


>UniRef50_Q3K1K4 Glucose-1-phosphate adenylyltransferase n=14 Tax=Lactobacillales
           RepID=GLGC_STRA1
          Length = 379

 Score =  232 bits (593), Expect = 1e-59,   Method: Composition-based stats.
 Identities = 72/321 (22%), Positives = 126/321 (39%), Gaps = 32/321 (9%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDK-PMIYYPLSVLMLAGIREILIITTPEDKG 59
           M  +ILAGG GTRL  +T+ ++K  +    +  +I + LS    +GI  + +IT  +   
Sbjct: 5   MLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALSNCANSGINNVGVITQYQPLE 64

Query: 60  YFQRLLGDGSEFGIQ-LE---YAEQP--------SPDGLAQAFIIGETFLN--GEPSCLV 105
                +G+GS +G+  ++      QP           G + A      +++       L+
Sbjct: 65  L-NTHIGNGSSWGLDGIDSGVTVLQPYSATEGNRWFQGTSHAIYQNIDYIDRINPEYVLI 123

Query: 106 LGDNIFFGQGFSPKLRHVAARTEGATVFGYQVM--DPERFGVVEFDDNFRAISLEEKPKQ 163
           L  +  +   +   L+         TV    V   +  RFG++  D N R +  EEKP+ 
Sbjct: 124 LSGDHIYKMNYDDMLQTHKDNLASLTVAVLDVPLKEASRFGIMNTDSNDRIVEFEEKPEH 183

Query: 164 PKSNWAVTGLYFYDSKVVE--YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAW 221
           PKS  A  G+Y +D K +        K          ++   YLE+G            W
Sbjct: 184 PKSTKASMGIYIFDWKRLRTVLIDGEKNGIDMSDFGKNVIPAYLESGERVYTY-NFDGYW 242

Query: 222 LDTGTHDSLIEASTFVQTVEKR-----QGFKIACLEEIAWRNGWLDDEG-----VKRAAS 271
            D GT +SL EA+      + +     + +KI     IA  N ++ ++      +     
Sbjct: 243 KDVGTIESLWEANMEYIGEDNKLHSRDRSWKIYSKNLIAPPN-FMTEDANVKDSLVVDGC 301

Query: 272 SLAKTGYGQYLLELLRARPRQ 292
            +A       L   ++ +P  
Sbjct: 302 FVAGNVEHSILSTNVQVKPNA 322


>UniRef50_A3DNE2 Nucleotidyl transferase n=8 Tax=Thermoprotei RepID=A3DNE2_STAMF
          Length = 233

 Score =  232 bits (592), Expect = 1e-59,   Method: Composition-based stats.
 Identities = 58/237 (24%), Positives = 98/237 (41%), Gaps = 11/237 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M  +ILAGG G RL P T  + K L+ + +KP++ + +  L   G  E +++     +  
Sbjct: 1   MMAVILAGGFGKRLRPYTEEIPKPLVSVAEKPILEWQIEWLKQYGFNEFVLLVGYRKEKI 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  +G G + G+++ Y  +  P G   A    E  L+ E   LVL  +I          
Sbjct: 61  IE-HIGSGGKLGVKVTYVVEDEPLGTGGAIKNAEHILSKEEKFLVLNGDILTNLNPMKLF 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
             +    E   V    +  P  +GV+E   + +     EKPK  +  W   G+Y      
Sbjct: 120 EKLDEHPEFVAVIA-SIPLPSPYGVLEI-KDSKVTGFVEKPKL-QDYWINAGIYAMKPSA 176

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
           ++Y  +     RG+LE T       + G +   +   G  W    T+  L EA+  +
Sbjct: 177 LKYFPE-----RGDLERT-AFPAMAKDG-VLGAVKYTGVFWKSVDTYKDLEEATKAI 226


>UniRef50_Q7X521 PtmE n=1 Tax=Campylobacter coli RepID=Q7X521_CAMCO
          Length = 220

 Score =  231 bits (591), Expect = 2e-59,   Method: Composition-based stats.
 Identities = 45/233 (19%), Positives = 95/233 (40%), Gaps = 13/233 (5%)

Query: 6   LAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQRLL 65
           +AGG GTRL  +T+   K +L +  KP++   +  L        +     +     +   
Sbjct: 1   MAGGLGTRLKELTKDTPKPMLKVGKKPILESIVQKLKEQNFENFIFCVNYKK-QIIEDYF 59

Query: 66  GDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHVAA 125
             G  FG+++ Y ++    G A A  + +       S +V+  +I     F+  L+    
Sbjct: 60  KKGKNFGVKIFYIKERKKLGTAGALSLIKQDFK--ESFIVMNADILTELNFNELLKAHKD 117

Query: 126 RTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEYAK 185
                +V   +      FGV+E +      ++ EKP Q        G+Y  + +++E   
Sbjct: 118 SKALMSVCVREFEQQIPFGVIEQNK-GFITNITEKPVQ--KFLVSAGIYVCEPEMLELLN 174

Query: 186 QVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
           + +      L++  + ++ ++ G +   L+     W+D G  D  ++A+   +
Sbjct: 175 KNEY-----LDMPELIKLAMQKGRVNTYLIHD--YWIDIGRLDEFVKANEDFK 220


>UniRef50_C2D9Q4 Glucose-1-phosphate adenylyltransferase n=1 Tax=Atopobium vaginae
           DSM 15829 RepID=C2D9Q4_9ACTN
          Length = 391

 Score =  230 bits (588), Expect = 3e-59,   Method: Composition-based stats.
 Identities = 61/263 (23%), Positives = 100/263 (38%), Gaps = 29/263 (11%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDK-PMIYYPLSVLMLAGIREILIITTPEDKGYF 61
            ++LAGG G+RL  +T+ ++K  +    K  +I + LS    +GI  + ++T  +     
Sbjct: 15  AMLLAGGQGSRLGALTKEIAKPAVSFGGKYRIIDFALSNCANSGIETVGVLTQYQPY-VL 73

Query: 62  QRLLGDGSEF-------GIQLE--YAEQP---SPDGLAQAFIIGETFL--NGEPSCLVLG 107
              LG G+ +       G+ +   +A Q       G A A      F+  N     L+L 
Sbjct: 74  HSYLGSGAAWNLNESDGGVSILPPFATQTGGAWYAGTADAVTQNLGFIEQNNPEYVLILS 133

Query: 108 DNIFFGQGFSPKLRHVAARTEGATVFGYQV--MDPERFGVVEFDDNFRAISLEEKPKQPK 165
            +  +   +   L          T+    V   +  RFG++  D+N R     EKPK+P 
Sbjct: 134 GDQLYSMDYQKMLDAHKRHGADLTIAVMPVAWEEASRFGIITQDENERITKFTEKPKKPD 193

Query: 166 SNWAVTGLYFYDSKVV------EYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGF 219
           SN A  G+Y ++  ++      +   Q    + G      I    LE G           
Sbjct: 194 SNLASMGIYIFNKDLLVTSLREDAINQTSEHDFG----GDIIPKLLEDGKKLYTY-EYRG 248

Query: 220 AWLDTGTHDSLIEASTFVQTVEK 242
            W D GT  S  E S  +     
Sbjct: 249 FWRDVGTISSYHETSMDLLGEHP 271


>UniRef50_A3WUE7 Nucleoside-diphosphate-sugar pyrophosphorylase n=1 Tax=Nitrobacter
           sp. Nb-311A RepID=A3WUE7_9BRAD
          Length = 349

 Score =  230 bits (588), Expect = 4e-59,   Method: Composition-based stats.
 Identities = 51/240 (21%), Positives = 88/240 (36%), Gaps = 16/240 (6%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +I+AGG G RL  +T    K +L +  +P++   +S     G   IL+      +   +
Sbjct: 122 VVIMAGGRGARLAELTSETPKPMLKVGSRPLLETIISSFSQQGFHRILLAVGYRAR-QIE 180

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEP--SCLVLGDNIFFGQGFSPKL 120
              GDGS FG+ + Y  +  P G A A  +    L  +P    +V   ++   + +   L
Sbjct: 181 DHFGDGSSFGVDISYLREDKPLGTAGALSL----LTEQPTLPLVVTNADLLTKEDYGHML 236

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                     T+          FGVV  +      ++EEKP Q  S     G+Y      
Sbjct: 237 DRHVESRVDGTMAVRTYDMQVPFGVVRENGAG-IEAIEEKPIQ--SFIVNAGMYVLSPSS 293

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           +    +         ++ S+    ++ G +T         WLD G       A+     +
Sbjct: 294 LGLIPKNAT-----FDMPSLFDAMMKHG-MTTRCHHIDGYWLDIGRMADYERANVDFAEI 347


>UniRef50_A9VB22 Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9VB22_MONBE
          Length = 342

 Score =  230 bits (588), Expect = 4e-59,   Method: Composition-based stats.
 Identities = 54/282 (19%), Positives = 94/282 (33%), Gaps = 32/282 (11%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +IL GG GTRL P+T  + K L+P  + PM+ + +  L+ AG+  +++      +  
Sbjct: 1   MKALILVGGFGTRLRPLTLSLPKPLVPFANLPMVMHQVEALVKAGVDHVVLAVNYRAE-- 58

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
                              Q        A  + E+ L       VL  ++     F   +
Sbjct: 59  -----------------IMQDEIK--KHAERLAESILRDGEPFFVLNSDVICQFPFKELV 99

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDN-FRAISLEEKPKQPKSNWAVTGLYFYDSK 179
               A  +  T+   +V +P ++GVV  D +        EKPK    N    GLY ++ +
Sbjct: 100 AFHKAHGKEGTILVTKVEEPSKYGVVVSDKDTGCIERFVEKPKIFVGNRINAGLYIFNPE 159

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           +++  +    S   E     I     E  NL    +     W+D G     ++       
Sbjct: 160 ILDRIEPRPTSIEKE-----IFPAMAETQNL--YAMDLPGFWMDVGQPPDYLKGMVLYLN 212

Query: 240 ---VEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
                +             +    L        A+       
Sbjct: 213 SVLENEPAKVTPTSTNGTEFIGPVLVHPTATIGANCKIGPNV 254


>UniRef50_B5ZR76 Nucleotidyl transferase n=12 Tax=Bacteria RepID=B5ZR76_RHILW
          Length = 237

 Score =  230 bits (587), Expect = 5e-59,   Method: Composition-based stats.
 Identities = 54/243 (22%), Positives = 95/243 (39%), Gaps = 12/243 (4%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           + +ILAGG GTRL P T  + K L+PI D P++   +  L+  G + I +    + +   
Sbjct: 4   RAVILAGGMGTRLRPYTVVLPKPLMPIGDYPILEVIIRQLISGGFQHITLAVNHQAE-LI 62

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLR 121
           +    DG ++G++++Y+ +  P G      + +       + LV+  +I     ++    
Sbjct: 63  KAFFQDGDKWGVRIDYSLEDQPLGTMGPLRLIKDL---PENFLVMNGDILTDLNYADFHD 119

Query: 122 HVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVV 181
                    T+          +GV++ ++        EKP          G+Y   S  V
Sbjct: 120 THVREGNIFTISSKTREHRIDYGVLDTNEAGLLTGFREKPTAEYK--VSMGVYMVSSGAV 177

Query: 182 EYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVE 241
           E+  Q     RG      +    L AG     +      WLD G  D    A    +T++
Sbjct: 178 EHIPQ-----RGAYGFDQLMLDLLAAGKP-ATVRDFPGYWLDIGRPDDYALAIEQFETMQ 231

Query: 242 KRQ 244
            R 
Sbjct: 232 SRF 234


>UniRef50_Q5UXR9 Glucose-1-phosphate thymidylyltransferase n=2 Tax=Halobacteriaceae
           RepID=Q5UXR9_HALMA
          Length = 396

 Score =  230 bits (587), Expect = 5e-59,   Method: Composition-based stats.
 Identities = 58/276 (21%), Positives = 112/276 (40%), Gaps = 15/276 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            ++LA G GTRL P+TR   K +LP  ++P++ +    L+ AGI +++++   + +   Q
Sbjct: 6   AVVLAAGEGTRLRPLTRNRPKPMLPAANRPILEHVFDALVEAGIEKLVVVVGYK-RDRVQ 64

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
              G     G+ + Y  Q    G   A +   + ++G    LV+  +         ++  
Sbjct: 65  DHFGPTYR-GVPISYVSQTKQLGSGHALLQARSVVDG--PVLVMNGDRLVDAATIEEVDT 121

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
             A T   ++   +  D  R+G VE  D    + + EKP+  +      G+Y +D  + E
Sbjct: 122 SYAETGNTSIAVLERQDTSRYGAVEVQDRD-IVDIVEKPQHDEFRLINGGVYAFDGDIFE 180

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEK 242
              +      GEL +T   ++ LE+    V+ +     W+D      L+  +  V     
Sbjct: 181 AIDETTRHA-GELALTDTIELLLESDR--VQAVEVDGMWVDATYPWDLLTVAREVL---- 233

Query: 243 RQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
               +   +E       W+D+       ++L     
Sbjct: 234 ---ARGRVVESARDEQVWVDNSARVHDEATLQSPVV 266


>UniRef50_C4XP25 Nucleotidyl transferase domain protein n=3 Tax=Proteobacteria
           RepID=C4XP25_DESMR
          Length = 247

 Score =  230 bits (587), Expect = 5e-59,   Method: Composition-based stats.
 Identities = 52/237 (21%), Positives = 90/237 (37%), Gaps = 12/237 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +ILAGG G+RL P T  + K L+PI   P++   +  L  AG   + +    + +   +
Sbjct: 5   AVILAGGLGSRLRPYTVVLPKPLMPIGPYPILEVVIRQLAAAGFTVVTLAVNHQAE-IIK 63

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
                G  +G+ + Y+ +  P G      + +       + L++  ++     F     H
Sbjct: 64  AYCNSGQRWGVHINYSMEKKPLGTMGPLKLLDDL---PDNFLIMNGDVLTDLNFETFYAH 120

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
             +R    TV   Q      FGV++FD++       EKP          G+Y    K++E
Sbjct: 121 HTSRANAFTVATCQREVRSEFGVLDFDESDTLHGFREKP--VVHYHVSMGIYMASRKILE 178

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           +           L +       + AG   V +      WLD G  D  + A    + 
Sbjct: 179 FIPDDVAYGFDNLVL-----DMMAAGKP-VHVCRHNGYWLDIGRPDDYMTAIDMFEA 229


>UniRef50_A6TK87 UTP-glucose-1-phosphate uridylyltransferase n=5 Tax=Bacteria
           RepID=A6TK87_ALKMQ
          Length = 307

 Score =  229 bits (586), Expect = 8e-59,   Method: Composition-based stats.
 Identities = 66/302 (21%), Positives = 117/302 (38%), Gaps = 35/302 (11%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K +I A G GTR  P T+ + K++LPI DKP + Y +   + +GI EILIIT        
Sbjct: 5   KAVIPAAGLGTRFLPATKALPKEMLPIVDKPTLQYIIEEAVDSGIEEILIITGRNKSS-I 63

Query: 62  QRLLGDGSEFG---------------------IQLEYAEQPSPDGLAQAFIIGETFLNGE 100
           +       E                       + + Y  Q  P GL  A    ++F+  E
Sbjct: 64  ENHFDKSIELELELEKKGKDELLKQVRAISDMVNIHYIRQKEPKGLGHAIHCAKSFIGNE 123

Query: 101 PSCLVLGDNIFF-GQGFSPKLRHVAARTEGATVFGYQVMDPE--RFGVVEF----DDNFR 153
           P  ++LGD+I    +    ++  +    +   +   +V      ++G+V+        ++
Sbjct: 124 PFAVMLGDDIVENDKPCLEQMMEMYDEYKTTILGVQEVPKESVNKYGIVDGMHIEGGIYK 183

Query: 154 AISLEEK--PKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLT 211
              L EK  P++  SN A+ G Y  + ++ +  +  KP + GE+++T   +    A    
Sbjct: 184 VKDLVEKPSPQEAPSNIAILGRYIINPEIFDILENTKPGKGGEIQLTDALKEL--AHREA 241

Query: 212 VELLGRGFAWLDTGTHDSLIEASTFVQTVEK--RQGFKIACLEEIAWRNGWLDDEGVKRA 269
           +          D G     +EA+       +  R+GF     + +         E V   
Sbjct: 242 MYAYVFEGRRHDVGDKQGFLEATVEFALKREDLREGFLNYLEDVVKKERESKALEEVAVT 301

Query: 270 AS 271
             
Sbjct: 302 TE 303


>UniRef50_C7NR86 Nucleotidyl transferase n=4 Tax=Halobacteriaceae RepID=C7NR86_HALUD
          Length = 439

 Score =  229 bits (585), Expect = 8e-59,   Method: Composition-based stats.
 Identities = 67/294 (22%), Positives = 117/294 (39%), Gaps = 19/294 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ +ILA G GTR+ P+T    K +LP+  +P++ +     + AG  E++++   E +  
Sbjct: 47  MQTVILAAGQGTRMGPLTESTPKPMLPVAGRPLVAHVADAAVDAGASELVVVVGYEAEA- 105

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   GD     + + +A Q    G A A       L+G     VL  +  +       +
Sbjct: 106 VRSFFGDTYR-DVPVTFAVQAEQAGTADAVRAARPELDGA--FAVLNGDNLYD---PAAV 159

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
             +       ++  Y+V DP  +GVV    +     + EKP  P + +A TG Y +    
Sbjct: 160 EQLFE--SAPSLATYEVDDPSNYGVVSIT-DGIVTDIVEKPADPPTTYANTGAYVFPEAA 216

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           +++   V  SERGE EIT +    ++A  +T   L R   W D G    L+EA+  +   
Sbjct: 217 IDWL-DVPESERGEYEITDVVAQVIDAHEVTPVPLSR---WRDVGRPWELLEANETLLAE 272

Query: 241 EKRQGFKIACLEEIAWRNGWLDDE-GVKRAASSLAKTGYGQYLLELLRARPRQY 293
                      ++   R   + +          +       Y+       P  Y
Sbjct: 273 LDGT-VDGTVSDDAELRGTVVVEAGATIEPGVVIEGPV---YVSRGASVGPNAY 322


>UniRef50_A3CRY9 UDP-glucose pyrophosphorylase n=2 Tax=Methanomicrobia
           RepID=A3CRY9_METMJ
          Length = 262

 Score =  229 bits (584), Expect = 1e-58,   Method: Composition-based stats.
 Identities = 73/243 (30%), Positives = 119/243 (48%), Gaps = 7/243 (2%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           +G+I A GSG+RL P T  + K+LLP+ +K +I + +  + LAGI +I+I+ +P   G  
Sbjct: 5   QGLIPAAGSGSRLGPFTNAIPKELLPVGEKAVIEHVVEAMSLAGITDIVIVVSPHKHGL- 63

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGF-SPKL 120
              LG G  FG+   Y  Q    GLA A   GE  ++G    +VLGDN F  + F +  +
Sbjct: 64  SDYLGSGKRFGVDFTYVVQDERLGLANAVAAGEHVIDG-TFAVVLGDNFFAPKTFLADLI 122

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK--QPKSNWAVTGLYFYDS 178
            + AA     TV   +V D  R G++  D + R   + EKP+     SN    G Y +++
Sbjct: 123 GYHAAHRPDTTVGVARVEDVTRHGIILPDGD-RVADMVEKPQPTAAPSNLGALGAYVFET 181

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
            + +   + KP  +GE ++T   ++ +  G      +      +D GT   L+ A+ +  
Sbjct: 182 SIFDAIARTKPGHKGEYQLTDAIRLEIAEGRDVRYRVI-DGIHIDVGTPRDLMRANEWYL 240

Query: 239 TVE 241
              
Sbjct: 241 REN 243


>UniRef50_Q49VP4 UTP--glucose-1-phosphate uridylyltransferase 2 n=216 Tax=cellular
           organisms RepID=GTAB2_STAS1
          Length = 289

 Score =  229 bits (584), Expect = 1e-58,   Method: Composition-based stats.
 Identities = 60/272 (22%), Positives = 99/272 (36%), Gaps = 35/272 (12%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K II A G GTR  P T+ + K++LPI DKP I Y +     AGI +I+I+T    +   
Sbjct: 6   KAIIPAAGLGTRFLPATKAMPKEMLPILDKPTIQYIVEEAARAGIEDIIIVTGKHKRA-I 64

Query: 62  QRLLGDGSEFGI---------------------QLEYAEQPSPDGLAQAFIIGETFLNGE 100
           +    +  E  +                      + Y  Q    GL  A      F+  E
Sbjct: 65  EDHFDNQKELEMILQEKGKTDLLEKVKYSTELANIFYVRQKEQKGLGHAIYSARQFIGDE 124

Query: 101 PSCLVLGDNIFFGQG--FSPKLRHVAARTEGATVFGYQVMDP--ERFGVVE----FDDNF 152
           P  ++LGD+I           +       +   +   +V +    R+G+++    F   +
Sbjct: 125 PFAVLLGDDIVESDNPAIKQLIEAYEETGKSV-IGVQEVDEAQTHRYGIIDPLQKFGRKY 183

Query: 153 RAISLEEKPKQ--PKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNL 210
                 EKPKQ    SN A+ G Y     + +Y         GE+++T   +    A   
Sbjct: 184 EVNEFVEKPKQGTAPSNLAIMGRYVLTPDIFDYLATQGEGAGGEIQLTDAIERLNRADQ- 242

Query: 211 TVELLGRGFAWLDTGTHDSLIEASTFVQTVEK 242
            V          D G     ++ +      ++
Sbjct: 243 -VYAYDFEGDRYDVGEKLGFVKTTIEYALKDE 273


>UniRef50_B8FX62 Glucose-1-phosphate adenylyltransferase n=2 Tax=Desulfitobacterium
           hafniense RepID=B8FX62_DESHD
          Length = 229

 Score =  229 bits (584), Expect = 1e-58,   Method: Composition-based stats.
 Identities = 61/241 (25%), Positives = 102/241 (42%), Gaps = 13/241 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ IILAGG G+RL P +R + K L PI DKP+    +  L  AG  E+++         
Sbjct: 1   MQTIILAGGRGSRLDPYSRILPKPLFPIGDKPIAAILIEQLKKAGTDEVIMCLGY-LSDL 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +    DGSEFG+ + Y+ +  P G A      E     + + +V+  +      F    
Sbjct: 60  LKTYFQDGSEFGLTIRYSVESEPLGTAGPLKGVEGL---QDNFVVVNGDELTTLDFRALY 116

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
            H  A     TV   +      FGV+E   + + I+  EKP    + WA  G+Y  +  +
Sbjct: 117 EHHRAVQADMTVAVQKKTTHSSFGVLEI-QDGQVIAYAEKPT--LNYWASMGIYVINKDI 173

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           + Y    +       ++ ++ Q  ++ G        +   W D GT   L +A   ++  
Sbjct: 174 LSYIPDNEK-----YDMPNLVQCLIQNGAKVSSYESQD-LWFDIGTLGDLEKAKEQLEKF 227

Query: 241 E 241
           +
Sbjct: 228 K 228


>UniRef50_C2G0W6 Nucleotidyl transferase n=1 Tax=Sphingobacterium spiritivorum ATCC
           33300 RepID=C2G0W6_9SPHI
          Length = 350

 Score =  228 bits (583), Expect = 1e-58,   Method: Composition-based stats.
 Identities = 50/239 (20%), Positives = 95/239 (39%), Gaps = 11/239 (4%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            I++AGG G RL P+T    K LL + DKP+I Y +  L   G+  I +      +   +
Sbjct: 122 AILMAGGEGRRLRPLTENTPKPLLRVGDKPIIEYNIDRLKEVGVSTINLSINYLGEQLVE 181

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
              GDGS+  I ++Y  +  P G     ++ + F       +V+  ++     F    + 
Sbjct: 182 -YFGDGSKKEINIKYVREDKPLGTIGGILLVDHF--NHDDIIVMNSDLLTNIDFGDFFKT 238

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
                    V          + V+E ++     SL+EKP+   + ++  G+Y     ++ 
Sbjct: 239 FKDTNADMAVAATSYHVDVPYAVLEVNETNTVRSLKEKPR--YTYYSNAGIYILKKDLLR 296

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVE 241
              + +        IT +    +E     +        WLD G H+   +A   ++ ++
Sbjct: 297 MIPKDEF-----FNITDLMDRVIEMNLKLITYPI-NGYWLDIGKHEDFKKAQEDIKHIK 349


>UniRef50_A9FF13 Putative sugar-phosphate nucleotide transferase n=1 Tax=Sorangium
           cellulosum 'So ce 56' RepID=A9FF13_SORC5
          Length = 236

 Score =  228 bits (583), Expect = 1e-58,   Method: Composition-based stats.
 Identities = 59/244 (24%), Positives = 101/244 (41%), Gaps = 11/244 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK ++LAGG G+RL P T  + K L+PI D  ++   L  L  AG+ ++++    +    
Sbjct: 1   MKAVVLAGGKGSRLRPYTALIPKPLMPIGDHTIVEILLRQLARAGVTDVVMCVGHQA-AL 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            + ++G+GS +G+++ Y  + +P G      + E  L      LV+  +I     F+   
Sbjct: 60  IEAVVGEGSRYGLRIAYQREDTPLGTVGPLRVIERDLP--ERFLVMNGDILSDLDFTALH 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           R   +     TV   +       GV++   + R +S  EKP    + W   G+Y     V
Sbjct: 118 RTGESAGSPLTVAVCERASKIDLGVLDLGADGRVVSFREKPT--YTFWVSMGIYAMSRDV 175

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           + +  + +P          +    L AG            WLD G  D   EA    +  
Sbjct: 176 LPFIPEGRPFGFD-----DLMHALLGAGEPVATFP-FRGHWLDIGRSDDFAEAQEEFEKN 229

Query: 241 EKRQ 244
            +R 
Sbjct: 230 RQRY 233


>UniRef50_C9XS92 Utp--glucose-1-phosphate uridylyltransferase (General stress
           protein 33) n=335 Tax=cellular organisms
           RepID=C9XS92_CLODC
          Length = 321

 Score =  228 bits (582), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 64/276 (23%), Positives = 109/276 (39%), Gaps = 33/276 (11%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K +I A G GTR  P T+   K++LPI DKP + Y +   + +GI EILIIT    K   
Sbjct: 7   KAVIPAAGLGTRFLPATKAQPKEMLPIVDKPTLQYIIEEAVASGIEEILIITGRNKKS-I 65

Query: 62  QRLLG-------DGSEFG--------------IQLEYAEQPSPDGLAQAFIIGETFLNGE 100
           +           D  + G              I + Y  Q  P GL  A      F+  E
Sbjct: 66  EDHFDKSVELELDLEKKGKKELLEVVQNISNMINIHYIRQKEPKGLGDAIYCARHFIGDE 125

Query: 101 PSCLVLGDNIFF-GQGFSPKLRHVAARTEGATVFGYQV--MDPERFGVVEFDD----NFR 153
           P  ++LGD+I         +L           +   +V   D  ++G++E  +     ++
Sbjct: 126 PFAVMLGDDIVDNDVPCLKQLTDAYEEYRTTILGVQKVNQEDTNKYGIIEAKNIEGRVYK 185

Query: 154 AISLEEKPK--QPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLT 211
              + EKP+  +  SN A+ G Y    ++ +  K + P + GE+++T   ++   +    
Sbjct: 186 VKDMVEKPESGKAPSNIAILGRYIITPEIFDILKDLPPGKGGEVQLTDALKIL--SKKEA 243

Query: 212 VELLGRGFAWLDTGTHDSLIEASTFVQTVEKRQGFK 247
           +          D G     +EA+      ++     
Sbjct: 244 MYAYNFEGKRYDVGDKLGFLEATVDFALKKEDLKED 279


>UniRef50_D0XT48 Nucleotidyl transferase n=1 Tax=Brevundimonas subvibrioides ATCC
           15264 RepID=D0XT48_9CAUL
          Length = 356

 Score =  228 bits (582), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 49/232 (21%), Positives = 81/232 (34%), Gaps = 12/232 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +I+AGG G RL P+T+   K +L +  +P++   +  L   G     +           
Sbjct: 124 VVIMAGGRGVRLAPLTQTCPKPMLKVAGRPLLESIIERLRDQGFSRFRLAVNY-LAEVIT 182

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
              GDGS  G++++Y  +  P G A A  +    +      +VL  ++     F   +  
Sbjct: 183 DHFGDGSAMGVEIDYLREDHPRGTAGALSLLREPVTA--PVVVLNGDVLTRLAFGDLIDF 240

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
                  AT+   +       GV E +   R  SL EKP       A  G+Y  D  ++ 
Sbjct: 241 HLEHGASATLCVREHQFQAPHGVAEIEGV-RLTSLREKPT--FRWQANAGIYCLDGSLLS 297

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
                 P      ++  +    +  G            WLD G       A 
Sbjct: 298 RIPADGP-----YDMPELLSALVGDGETVCAYPMHE-YWLDIGRPPDFESAQ 343


>UniRef50_UPI000197319A nucleoside-diphosphate-sugar pyrophosphorylase n=1 Tax=Clostridium
           sp. M62/1 RepID=UPI000197319A
          Length = 236

 Score =  228 bits (581), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 50/240 (20%), Positives = 93/240 (38%), Gaps = 10/240 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ I+LAGG GTRL  +     K +  I  +P + Y +  L   GI +I+     +    
Sbjct: 1   MQAILLAGGLGTRLRSVVSDRPKPMALIEGRPFMEYVVRGLARHGIADIIFAVGYK-GSM 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +    DGS  GI+  YA +    G A A      F+  E    VL  + ++   +S   
Sbjct: 60  VEEHFRDGSNLGIRASYAYEEELLGTAGAIKNAGRFVTEERFF-VLNADTYYSLDYSRLA 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK-QPKSNWAVTGLYFYDSK 179
           +  A ++    +   +V D  R+G      +       EK + + +      G+Y  D +
Sbjct: 119 KLQAEKSLDMALVLREVDDISRYGAATLT-DGMLTGFNEKLEGEKRPGTINGGVYLMDRR 177

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           +++   + K S   E+        +++ G      +     ++D G  +        V+ 
Sbjct: 178 LLKEIPEGKVSLEQEM-----IPRWMKEGKRLGGFV-NEGYFIDIGIPEDYFRFQEDVKK 231


>UniRef50_B7KYN3 Nucleotidyl transferase n=1 Tax=Methylobacterium chloromethanicum
           CM4 RepID=B7KYN3_METC4
          Length = 360

 Score =  228 bits (581), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 50/241 (20%), Positives = 90/241 (37%), Gaps = 12/241 (4%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +++AGG G RL P+T  + K L+ +  +P++   +      G     I          +
Sbjct: 123 VVLMAGGKGQRLLPLTEKLPKPLIQVAGRPILEIIIRRFAAQGFWRFAISVNF-LGHIIK 181

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
              GDGS+ G+ + Y E+ S  G A +  +       + + LV   ++     +   L  
Sbjct: 182 EHFGDGSQLGVSISYIEEGSSLGTAGSLGLLTE--TPDRAVLVSNGDLLTKLKYDWMLDF 239

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
                  ATV   +      FGVV    +     ++EKP      +   G+Y  +  V +
Sbjct: 240 HLQHGASATVAVREYDMQVPFGVVGT-QDGFVTQIDEKPVH--RFFISAGVYILEPSVFD 296

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEK 242
              + +  +     +  + Q  +   +       R   WLD G HD L  A    +  E+
Sbjct: 297 LVAKDERVD-----MPQVLQRLISRLDKVAAFPLRE-RWLDIGRHDDLERAEAEFEISEQ 350

Query: 243 R 243
            
Sbjct: 351 D 351


>UniRef50_A9BBF8 Nucleoside-diphosphate-sugar pyrophosphorylase n=1
           Tax=Prochlorococcus marinus str. MIT 9211
           RepID=A9BBF8_PROM4
          Length = 353

 Score =  228 bits (581), Expect = 3e-58,   Method: Composition-based stats.
 Identities = 47/235 (20%), Positives = 91/235 (38%), Gaps = 12/235 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +I+AGG G+RL P T    K +L +  KP+I   +   +  G+ +  I      +    
Sbjct: 125 VVIMAGGKGSRLKPHTNNCPKPMLHVNGKPIIEIIIRNCIDFGLTKFFISVNYLKEQII- 183

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
             LGDGS  G+ +EY  +  P G A +  +    +    + L+L  ++         +  
Sbjct: 184 NHLGDGSTLGVDIEYLYEDMPLGTAGSLHLLPKDIK--ETILILNGDVLTNLNLHGLINF 241

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
                   T+   +      +GV++ D       L+EKP    S     G+Y  +  ++ 
Sbjct: 242 HQENNADITLCAREESTLIPYGVIKLDGIN-VEELKEKPIH--SYLVNAGIYLINPGILR 298

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
             +         L++ ++     + G+  +        W+D G  ++L +A    
Sbjct: 299 LIESNSY-----LDMPNLILKAKKNGSHIIAFPIHE-YWIDVGRPETLKQAHNEW 347


>UniRef50_Q7MEE9 Glucose-1-phosphate adenylyltransferase 2 n=58 Tax=Proteobacteria
           RepID=GLGC2_VIBVY
          Length = 404

 Score =  228 bits (581), Expect = 3e-58,   Method: Composition-based stats.
 Identities = 60/274 (21%), Positives = 105/274 (38%), Gaps = 31/274 (11%)

Query: 4   IILAGGSGTRLHPITRGVSKQLLPIYDK-PMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
           +ILAGG G+RL P+T   +K  +P   K  +I + L+  + +G+R+IL++T  +     +
Sbjct: 7   VILAGGMGSRLSPLTDDRAKPAVPFGGKYRIIDFTLTNCLHSGLRKILVLTQYKSHSLQK 66

Query: 63  RLLGDGSEFGIQL-EYAEQ---------PSPDGLAQAFIIGETFLNGEP--SCLVLGDNI 110
            L    S F  +L EY               +G A A       L        +VL  + 
Sbjct: 67  HLRDGWSIFNPELGEYITSVPPQMRKGGKWYEGTADAIYHNLWLLERSEAKYVMVLSGDH 126

Query: 111 FFGQGFSPKLRHVAARTEGATVFGYQVM--DPERFGVVEFDDNFRAISLEEKPKQPK--- 165
            +   ++P L    A     TV    V   + + FGV+  D++ R  S  EKP+ P    
Sbjct: 127 IYRMDYAPMLEEHIANNAALTVACMDVNCKEAKAFGVMGIDEHHRVHSFVEKPQNPPHLP 186

Query: 166 ----SNWAVTGLYFYDSKVVE--YAKQVKPSERGELEITSINQMYLEAGNLTVE------ 213
                +    G+Y +  +V++    +              I    ++ G++         
Sbjct: 187 NDPERSLVSMGIYIFSMEVLQQALIEDADNDASSHDFGKDIIPKLIDTGSVFAYKFCGSK 246

Query: 214 -LLGRGFAWLDTGTHDSLIEASTFVQTVEKRQGF 246
             + +   W D GT DS  +A+  +         
Sbjct: 247 GRVDKDCYWRDVGTIDSFYQANMDLLEPIPPMNL 280


>UniRef50_Q0W805 Putative glucose-1-phosphate thymidylyltransferase n=2
           Tax=Euryarchaeota RepID=Q0W805_UNCMA
          Length = 332

 Score =  227 bits (580), Expect = 4e-58,   Method: Composition-based stats.
 Identities = 59/295 (20%), Positives = 121/295 (41%), Gaps = 20/295 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +I A G+G RL+P T    K ++ +  KP+I + L   +     E++I+     +  
Sbjct: 1   MKVVIPAAGAGKRLYPHTYTKPKPMVYVAGKPIIGHILDKAVDLQPDELIIVVGYMKEKL 60

Query: 61  FQRLLGDGSEFGI--QLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSP 118
              +  D    GI  ++ Y  Q    GL  +  +    ++  P  + L  ++ F  G+S 
Sbjct: 61  IDYV--DEHYCGIFKKITYVHQDQQLGLGHSIYVAREAIDDAPIMIAL-GDMIFKGGYSD 117

Query: 119 KLRHVA-ARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYD 177
             R  A       ++   ++ +P  +G+V  + +     + EKPK+  S   + G+YF D
Sbjct: 118 FARLHACNGKCSGSIGVKEIDNPSHYGIVFLNGDGTIKKMVEKPKKSSSRLGIAGVYFID 177

Query: 178 --SKVVEYAKQ-VKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAS 234
               ++   ++ V+    GE+++T   Q  +EAG+          +W D G  +SL+E +
Sbjct: 178 DTPGLIRALEKVVENRGEGEVQLTDALQKAIEAGSD--YKPFEVSSWYDCGRPESLLEVN 235

Query: 235 TFVQTVEKRQGFKI---------ACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQ 280
             +   + +  +K             +++   N  +         + +  +    
Sbjct: 236 RLLLAEKSKMSWKPRNSILIEPVCVGQDVEIENSIIGPNVSISDGARITSSIIED 290


>UniRef50_Q9YCT0 Glucose-1-phosphate thymidylyltransferase n=1 Tax=Aeropyrum pernix
           RepID=Q9YCT0_AERPE
          Length = 355

 Score =  227 bits (579), Expect = 4e-58,   Method: Composition-based stats.
 Identities = 79/281 (28%), Positives = 129/281 (45%), Gaps = 11/281 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +KG+ILA G G+RL P T    K L+P+  KP+I Y +  L+   +R+I ++        
Sbjct: 2   VKGLILAAGEGSRLRPFTFSRPKHLIPLLGKPIIQYAIDDLVSINVRDIGVVVGY-FGDK 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETF-LNGEPSCLVLGDNIFFGQGFSPK 119
            +  LG+ S FG +  Y  Q    G+A A           +   + LGDNI  G G S  
Sbjct: 61  IKEFLGEDSRFGAKFTYIVQKKRLGIAHAIYRAIKQGFIDKEFIVYLGDNILSG-GISRH 119

Query: 120 LRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFY-DS 178
           ++          +   +V DP RFG+     + + + L EKP++  S+ AV G+Y + D 
Sbjct: 120 VKSWGEAGSEVHILLTKVRDPGRFGIAVL-RDGKILKLVEKPQEHISDLAVVGVYMFRDP 178

Query: 179 KVVE-YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV 237
           ++V      +KPS RGE EIT + Q +++ G      L     W D GT++ L++A  ++
Sbjct: 179 ELVAKAFSTLKPSWRGEYEITDLIQWFVDKGYKVTFSLVT-GWWKDVGTYEGLLDA-IYL 236

Query: 238 QTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
                +   +     E+  R   + +EG     +      Y
Sbjct: 237 LLDNVKPRVEGKIEGEV--RGRVVVEEGAIVEGTVH-GPAY 274


>UniRef50_C8PNH3 Nucleotidyl transferase n=6 Tax=Bacteria RepID=C8PNH3_9SPIO
          Length = 435

 Score =  227 bits (579), Expect = 4e-58,   Method: Composition-based stats.
 Identities = 62/320 (19%), Positives = 120/320 (37%), Gaps = 35/320 (10%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK IILAGG GTR+  I   + K ++ +  KP++ Y +  L   G+ +I ++        
Sbjct: 1   MKAIILAGGKGTRIASIRSDIPKPMIELCGKPILQYQIENLRSFGLTDITLVIGY-LGDV 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +   G GS+FG+ + Y  +P P G A A              L+L  +I F   F+  +
Sbjct: 60  IKNYFGSGSQFGVNISYFAEPEPLGTAGALFKMSGLTED---FLLLCGDIIFDVDFARFI 116

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFD------------DNFRAISLEEKPKQ--PKS 166
                 T  A++  +    P    ++  +            D+ + I    K  +     
Sbjct: 117 TFHNQHTAWASLMSHPNSHPYDSSLLITEILPPNKLGGLPYDSHKVIQWLNKEDERVYYK 176

Query: 167 NWAVTGLYFYDSKVVEYAKQVKPSERGELEIT-SINQMYLE---AGNLTVELLGRGFAWL 222
           N    G+     K++E AK +  ++   L     +++  L+   A           +   
Sbjct: 177 NRVNAGIQIISPKLLESAKDILVADNNVLPDKIDLDRGVLKPNIANGRIFAYDTPEYI-K 235

Query: 223 DTGTHDSLIEASTFVQT--------VEKRQGFKIACLEEIAWRNGWLDDEG----VKRAA 270
           D GT D   +    +++        + +++   +     I   NG++        +  AA
Sbjct: 236 DMGTPDRYYQTEADIKSGLLQSRNLIHEQKAVFLDRDGTINKENGFISHPDDFILLSDAA 295

Query: 271 SSLAKTGYGQYLLELLRARP 290
            ++       YL  ++  +P
Sbjct: 296 EAIKMINQSGYLAIVITNQP 315


>UniRef50_C1XRH9 Histidinol-phosphate phosphatase family protein n=1 Tax=Meiothermus
           silvanus DSM 9946 RepID=C1XRH9_9DEIN
          Length = 408

 Score =  226 bits (578), Expect = 6e-58,   Method: Composition-based stats.
 Identities = 64/302 (21%), Positives = 110/302 (36%), Gaps = 30/302 (9%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           + +ILAGG GTRL  +TR   K LLP+  KP + Y L  L   G   +L +   +     
Sbjct: 7   QAVILAGGLGTRLGALTRETPKPLLPVAGKPFLDYLLWNLKRHGFERVLFLLGYKAMRII 66

Query: 62  QRLLGDGSEFG----------IQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIF 111
           +   G G+  G          +++EYA +  P G   A  + + +L  +   L+L  +  
Sbjct: 67  EHY-GSGAGHGLADDAQRNTRLEVEYAVETEPMGTGGALRLAKDYL--DERFLLLNGDTL 123

Query: 112 FGQGFSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVT 171
           F   +             A V   +V D  R+G V  + N R I   EK  +        
Sbjct: 124 FDFNYLDLALL----EGPAAVALRRVPDTARYGRVRLEGN-RIIGFGEKEGKGPG-LING 177

Query: 172 GLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLI 231
           G++      VE   +   S         +    +E G L  +       +LD G  ++  
Sbjct: 178 GVHVLSRPAVELLPEGVSSLE-----RDLFPRLVERGELLGK--PYEGFFLDIGLPEAYT 230

Query: 232 EASTFVQTVEKRQGFKIACLEEIAWRNGWLDDEG----VKRAASSLAKTGYGQYLLELLR 287
           EA   +    K+    +     +    G+          + A  ++       YL+ ++ 
Sbjct: 231 EAQKALPAWRKKPAVFLDRDGVLNHDEGYTHRPEQWRWTEGAVEAVKWLNDRGYLVLVIT 290

Query: 288 AR 289
            +
Sbjct: 291 NQ 292


>UniRef50_Q54800 UTP--glucose-1-phosphate uridylyltransferase n=15 Tax=Bacteria
           RepID=CAP3C_STRPN
          Length = 306

 Score =  226 bits (578), Expect = 6e-58,   Method: Composition-based stats.
 Identities = 57/281 (20%), Positives = 111/281 (39%), Gaps = 37/281 (13%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
           K +I A G GTR  P T+ ++K++LPI D+P I++ +   + +GI +IL++T    +   
Sbjct: 6   KAVIPAAGLGTRFLPATKALAKEMLPIVDRPTIHFVIEEALRSGIEDILVVTGKSKRS-I 64

Query: 62  QRLLGDGSEF--------------------GIQLEYAEQPSPDGLAQAFIIGETFLNGEP 101
           +       E                      I++ +  Q SP GL  A +  ++F+  +P
Sbjct: 65  EDYFDSTFELEYSLRKQGKMELLKSVNESTDIKVHFVRQSSPRGLGDAVLQAKSFVGDDP 124

Query: 102 SCLVLGDNIF-----FGQGFSPKLRHVAARTEGATVFGYQV--MDPERFGVVEF-----D 149
             ++LGD++           + +L      T+ +T+    V   D   +GV+       +
Sbjct: 125 FVVMLGDDLMDITDSTAVPLTRQLMDDYNATQASTIAVMPVRYEDVSSYGVISPRLESSN 184

Query: 150 DNFRAISLEE--KPKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEA 207
             +   +  E  KP++  SN A+ G Y    ++    +  KP    E+++T         
Sbjct: 185 GLYSVDAFVEKPKPEEAPSNLAIIGRYLLTPEIFSILETQKPGAGNEIQLTDAIDTL--N 242

Query: 208 GNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEKRQGFKI 248
              +V          D G   + ++ S        +    +
Sbjct: 243 KTQSVFAREFVGKRYDVGDKFNFMKTSIDYALQHPQIKESL 283


>UniRef50_A4GI83 Mannose-1-phosphate guanyltransferase n=1 Tax=uncultured marine
           bacterium HF10_29C11 RepID=A4GI83_9BACT
          Length = 342

 Score =  226 bits (577), Expect = 8e-58,   Method: Composition-based stats.
 Identities = 55/285 (19%), Positives = 107/285 (37%), Gaps = 21/285 (7%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M GII+AGG G+RL PIT    K ++ +  +P+I +    ++  G+  I++ T    +  
Sbjct: 1   MLGIIMAGGQGSRLRPITDARPKPMVEVLGRPVIDFVKDSMVQGGVDNIIVTTGYRGEML 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            + + G  +E        ++ +P G A +  +    +    + ++   +       +  +
Sbjct: 61  AEHVKGWNAEH-CSARINQESTPMGTAGSVRLLLNEIT--ETVIIGSGDSVASFDVASLI 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVV--------EFDDNFR---AISLEEK--PKQPKSN 167
                    AT+  ++V DP  FG+V        E D   R       +EK  P++  SN
Sbjct: 118 EAHKRSGAKATMALWEVEDPSPFGIVGLSPTKNGEVDGQLREGYIRKFKEKPTPEEAFSN 177

Query: 168 WAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTH 227
               GLY  + +V+    + +  +       ++    L+ G            W D G+ 
Sbjct: 178 VINAGLYILEPEVMALVPEGEKYD----FSRNLFPRLLDMGWPM-YAQAINGVWFDVGSP 232

Query: 228 DSLIEASTFVQTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASS 272
             LI A   +        F +     I   + +     V   ++ 
Sbjct: 233 QELIRAQNVLIQQRDELPFPLPEGSRIVQGSFFHPTAEVSDDSNV 277


>UniRef50_D2PFA0 Nucleotidyl transferase n=10 Tax=Sulfolobus RepID=D2PFA0_SULIS
          Length = 237

 Score =  226 bits (576), Expect = 1e-57,   Method: Composition-based stats.
 Identities = 56/247 (22%), Positives = 104/247 (42%), Gaps = 14/247 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M  +ILAGG G RL P+T    K L+ +  +P+I + +S L   GI   +I+T  + +  
Sbjct: 4   MHAVILAGGYGKRLRPLTDDRPKPLIEVAGRPIIEWQISWLKQFGITSFVILTGYKWEVL 63

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            + L  +    GI   ++ +  P G   A    E  L+ E + +VL  +I      S   
Sbjct: 64  IKWLSENEKRLGISTYFSIEEEPLGTGGALRKVERLLSTENTFIVLNGDIITNLDISKLK 123

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
               +     T+    V     +G+VE  D+ + I  +EKP   ++ W   G+Y    ++
Sbjct: 124 ---ISNENVMTMSL--VPLKSPYGIVETKDD-KIIDFKEKP-ILENYWINAGVYLMRKEI 176

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
            +Y  +     +G++E  +  +  L   +L + +      W    T   + E S  +  +
Sbjct: 177 FKYLPE-----KGDMEKLTFPK--LAKESLLIGIKYYDVYWRSIDTIKDIEEVSEDLIKM 229

Query: 241 EKRQGFK 247
           +     +
Sbjct: 230 KNGLSSE 236


>UniRef50_A1VGN4 Nucleotidyl transferase n=1 Tax=Desulfovibrio vulgaris DP4
           RepID=A1VGN4_DESVV
          Length = 367

 Score =  226 bits (576), Expect = 1e-57,   Method: Composition-based stats.
 Identities = 49/236 (20%), Positives = 93/236 (39%), Gaps = 12/236 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +I+ GG G+RL  +T    K +L +  KP++   +  ++ AGI      T    K   +
Sbjct: 125 AVIMCGGLGSRLGHLTHNCPKPMLEVGGKPILERIMCSIIQAGISRFFFATHY-LKEKIE 183

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
              G+G ++G+Q+EY ++    G   A  +   ++   P  L++  +I         L  
Sbjct: 184 CYFGNGEKWGVQIEYLKEKKRMGTGGALSL-MPYVPSHP-MLIMNGDILTEFNIRHLLDF 241

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
            +     AT+   +      +GVV  +     + ++EKP    S +   G+Y  +  +VE
Sbjct: 242 HSMTNSIATMAIAEYCYQNPYGVVRHEGTM-LLDIDEKPTN--SWFINAGIYVAEPSLVE 298

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
              Q        +++ ++     + G            WLD G       A   +Q
Sbjct: 299 KVPQDTF-----IDMPTLLLNAKKKGETISIFPICE-KWLDIGREPDYRSAQRMIQ 348


>UniRef50_Q8CUH8 Spore coat polysaccharide synthesis (Glucose-1-phosphate
           thymidyltransferase) n=1 Tax=Oceanobacillus iheyensis
           RepID=Q8CUH8_OCEIH
          Length = 239

 Score =  225 bits (575), Expect = 1e-57,   Method: Composition-based stats.
 Identities = 99/242 (40%), Positives = 149/242 (61%), Gaps = 4/242 (1%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+ILA G GTRLHP+T+ ++K L+PI   PMIYYP+  L    I EILI T  +D   
Sbjct: 1   MKGMILARGKGTRLHPLTKVINKHLIPIGKYPMIYYPIFKLREVDITEILITTNQQDIPL 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F+ LLGDG + G+++ +  Q    G+  A ++ +TF+  +   ++LGDNIF      P +
Sbjct: 61  FRELLGDGRDLGVRIHFEAQQQAIGIPDAILLSKTFVGSDKLTVILGDNIFHD-SLIPYV 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFR-AISLEEKPKQPKSNWAVTGLYFYDSK 179
           +    ++ GA +    V DP R+G+  FD + +  +S+EEKP    SN+ VTG+Y Y ++
Sbjct: 120 QSYEKQSTGAKILLKTVSDPNRYGIATFDKSQKNILSIEEKPSDSSSNYCVTGIYMYGTE 179

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           V E+ KQ+ PS RGELEIT +N +YL+   LT ++L     W+D GT+DS+ +A+  +  
Sbjct: 180 VFEFIKQITPSSRGELEITDVNNLYLQKSKLTFDVLPN--WWIDAGTYDSIFQANQIILK 237

Query: 240 VE 241
            E
Sbjct: 238 NE 239


>UniRef50_B9L1J9 Glucose-1-phosphate adenylyltransferase n=15 Tax=Bacteria
           RepID=GLGC_THERP
          Length = 428

 Score =  225 bits (575), Expect = 1e-57,   Method: Composition-based stats.
 Identities = 62/292 (21%), Positives = 108/292 (36%), Gaps = 28/292 (9%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDK-PMIYYPLSVLMLAGIREILIITTPEDKGYF 61
            +ILAGG G RL  ++R  +K  +P   K  +I + LS  + +G+ ++ ++T        
Sbjct: 6   VMILAGGQGERLSILSRQRAKPAVPFGGKYRIIDFALSNCVNSGLYDVAVLTQYRPHSL- 64

Query: 62  QRLLGDGSEFGIQLE-----YAEQP--------SPDGLAQAFIIGETFLNGEPS--CLVL 106
              +G G  + +  E        QP           G A A      ++   P    L+L
Sbjct: 65  NEHIGHGRPWDLDRERNGGVVILQPYLGRSTSGWYRGTADAVYHNLFYITRRPYRDVLIL 124

Query: 107 GDNIFFGQGFSPKLRHVAARTEGATVFGYQVM--DPERFGVVEFDDNFRAISLEEKPKQP 164
             +  +   + P +     R    T+    V   +  RFGVV   ++   +  EEKP++P
Sbjct: 125 AGDHVYAMDYRPMIAQHRERCADVTIAVQPVDWREASRFGVVIVAEDGWVVDFEEKPERP 184

Query: 165 KSNWAVTGLYFYDSKVVEYAKQVKPSERGEL--EITSINQMYLEAGNLTVELLGRGFAWL 222
           +SN A  G+Y +   ++         +  E       +    +      V        W 
Sbjct: 185 RSNLASMGIYLFRRNLLLDLFTRDHPDAPEFIDFGRDVIPYLIRTAR--VATYRFDGYWQ 242

Query: 223 DTGTHDSLIEASTFVQTVEKR-----QGFKIACLEEIAWRNGWLDDEGVKRA 269
           D GT  S  EA+  +   E +       ++I    E       L+   V R+
Sbjct: 243 DVGTVQSYWEANMALLEDEPKLNLYDPNWRIHTRSEERPPAKILEGATVIRS 294


>UniRef50_Q8TWW4 Nucleoside-diphosphate-sugar pyrophosphorylase involved in
           lipopolysaccharide biosynthesis; translation initiation
           factor eIF2B subunit n=1 Tax=Methanopyrus kandleri
           RepID=Q8TWW4_METKA
          Length = 356

 Score =  225 bits (574), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 63/283 (22%), Positives = 108/283 (38%), Gaps = 15/283 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           +  ++LAGG GTRL P+T    K L+PI  KP+I + +  L    +  + I      +  
Sbjct: 3   VDAVVLAGGFGTRLRPLTWDTPKPLVPILGKPLIEWVIRSLPR-DVVHVHIAAGFSSEKL 61

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            + +  D      +L    +P P   A A          + + +    +I         L
Sbjct: 62  ERYVESD--PLPRKLHLKVEPKPLDTAGAIKFACRDSTAD-AFVAFNGDIVSSLDVRQML 118

Query: 121 RHVAARTEGATVFGYQV--MDPERFGVVEFDDNFRAISLEEK--PKQPKSNWAVTGLYFY 176
           +        AT+  Y V   +  RFGVV+ DD+ R +   EK  P++  SN    G Y  
Sbjct: 119 KFHREHDGIATIALYPVPEDEVSRFGVVDLDDDDRILDFVEKPEPEEAPSNLINAGAYVL 178

Query: 177 DSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTF 236
           D +V++Y  + +P          I     E G L          W+D G  ++ +EA   
Sbjct: 179 DREVLDYIPEGRP----VSIEREIFPKLAEEGLL--YGFKFEGYWVDVGLPETYLEAHRV 232

Query: 237 VQTVE-KRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
           +   E   +    A + +   +   +     +  +S +    Y
Sbjct: 233 LMEHECSGKSVVGARITDTDLKPPVVAAPMTELRSSEIGPYVY 275


>UniRef50_Q89HJ6 Blr5994 protein n=1 Tax=Bradyrhizobium japonicum RepID=Q89HJ6_BRAJA
          Length = 363

 Score =  225 bits (574), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 48/240 (20%), Positives = 90/240 (37%), Gaps = 12/240 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +I+AGG G RL  +TR V K +L +  +P++   +  ++  G R I I    + +   +
Sbjct: 136 VLIMAGGLGERLGALTRDVPKPMLNVGGRPLLETIVRNVVQQGFRNIYISVNYKAET-IK 194

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
               DG+ FG  ++Y  +    G A A  +       +   +V   +I     +   L  
Sbjct: 195 DYFADGAAFGANIQYVHETERLGTAGALGLFPA--PPDLPMIVTNGDILTTINYGALLDF 252

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
                  AT+   +      +GVV    +    ++ EKP +  S +   G+Y   S V  
Sbjct: 253 HNGTPAEATMAVREHKVHVPYGVVST-SDGFLQAIREKPTE--SWFVSAGIYVIGSSVFG 309

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEK 242
           +           +++ ++ +  +           R   WLD G  +   +A      V  
Sbjct: 310 HVAPGVS-----IDMPTVLERVIAGKGRVAVYPIRE-YWLDIGRLEDFEQAHAEFHEVFP 363


>UniRef50_B3PKU9 Nucleotidyltransferase family protein n=1 Tax=Cellvibrio japonicus
           Ueda107 RepID=B3PKU9_CELJU
          Length = 234

 Score =  225 bits (574), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 53/239 (22%), Positives = 99/239 (41%), Gaps = 10/239 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +ILA G G R+ P+T  + K +LP+  KP++ Y L  L  AGI +++I         
Sbjct: 1   MKAMILAAGLGQRMRPLTNHLPKPMLPLGGKPLLDYHLEKLPAAGITQVIINLAY-LGDK 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  +GDG  +G+++ Y+E+P P     A +     L   P  L+   +++         
Sbjct: 60  IRAYVGDGQRYGLEVIYSEEPEPLETGGALLKALPLLGESPFLLI-NGDVWCDLDLRQFS 118

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
           +H    T+   +      D    G  +F    +   L +  +Q    +   G+     ++
Sbjct: 119 QHRLRETQMGHLLLIPNPDFHPRG--DFALGAQQYLLPDPQQQHPWRYTFAGISLLRPEL 176

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
           +       P  R +  +  + +  ++ G L+ E+      W D GT + L      +Q 
Sbjct: 177 IA----TYPHRRHKFPLVEVLRHAIDRGQLSAEV--HTGQWSDIGTPERLHALEQQLQA 229


>UniRef50_C7PPE5 Nucleotidyl transferase n=1 Tax=Chitinophaga pinensis DSM 2588
           RepID=C7PPE5_CHIPD
          Length = 231

 Score =  224 bits (572), Expect = 3e-57,   Method: Composition-based stats.
 Identities = 46/237 (19%), Positives = 90/237 (37%), Gaps = 10/237 (4%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            I+LAGG GTRL  +     K + P+ DKP ++Y L  L+  GI  +++    + +   +
Sbjct: 5   CIVLAGGLGTRLRSVVADKPKCMAPVNDKPFLFYLLQYLIKQGITHVVLSLGYKSEQVIE 64

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
                G    + L YA +  P G   A +   + + G+   +V   + FF    S   + 
Sbjct: 65  WCEQAG--LPLTLSYAIEEEPLGTGGAILHAISHIKGDECFIV-NGDTFFEVSLSDFHQF 121

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
                   T+    +   ER+G V+ D   R  +  EK K  +      G+Y   S+ ++
Sbjct: 122 HQQTQSKLTLALKPMRQFERYGSVQLDQQGRITAFLEK-KYCEEGLINGGVYVASSEYLQ 180

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
                    +       + +  ++   +   +      ++D G      +     ++
Sbjct: 181 SLGL----PQQFSFEKEVLEPQVQNNQVFGFV--SDTYFIDIGIPADYEQVQVDFRS 231


>UniRef50_Q1J1Y9 Nucleotidyl transferase n=2 Tax=Deinococcus RepID=Q1J1Y9_DEIGD
          Length = 365

 Score =  224 bits (572), Expect = 3e-57,   Method: Composition-based stats.
 Identities = 80/291 (27%), Positives = 127/291 (43%), Gaps = 16/291 (5%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKG+ILA G G+RL P++ G  K  +PI   P+I + +  +  AG+ E+ ++T+  ++  
Sbjct: 21  MKGVILAAGRGSRLFPVSAGRPKHAVPIAGVPIIAWAVRAVREAGVEEVAVVTSSNNEAA 80

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +    D       L +  Q  P G   A +    FL G P+ L LGDN+F     +P  
Sbjct: 81  LREATRDEG----PLTFLRQEEPRGTGDAVLAARAFLEGSPALLYLGDNLFAD-PLTPLT 135

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
             +  +   A +   QV DP  +GV    DN    +L+EKP  P S+ A  G++ +   V
Sbjct: 136 EAL--QDADAALGVKQVPDPSAYGVAAVRDN-LLTNLDEKPAAPASDLAACGVFAFHPHV 192

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV 240
           +E   +++PS RGE+E        + AG     +      W D GT   L+ AS    + 
Sbjct: 193 LEEVARLEPSVRGEIEFPQALLRVIAAGGRVRAV-TFPGFWSDAGTPADLLSASAHFLS- 250

Query: 241 EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRARPR 291
                       E+  R   L    V  A +++  +     +L    A  R
Sbjct: 251 ----KLAPRVDGEV--RRSSLSGPVVIEAGATVEDSLLVGPVLIGAGASVR 295


>UniRef50_B6AEL1 Nucleotidyl transferase family protein n=1 Tax=Cryptosporidium
           muris RN66 RepID=B6AEL1_9CRYT
          Length = 441

 Score =  224 bits (572), Expect = 3e-57,   Method: Composition-based stats.
 Identities = 47/252 (18%), Positives = 91/252 (36%), Gaps = 17/252 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK IIL+GG G+RL P+T    K ++ + + P+I + +S  +  G++ I++      +  
Sbjct: 1   MKAIILSGGFGSRLRPLTLSKPKPIIELCNIPLIEFQISQFVEVGVKNIILAVNYLSEEL 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNG----EPSCLVLGDNIFFGQGF 116
            + +     ++G+++  + +  P G A   ++ + F+           V   +I      
Sbjct: 61  REPIKNIEKKYGVKINASIEEKPLGTAGPILLAKRFIEDNIITNEPFFVCNSDIVCNFPL 120

Query: 117 SPKLRHV------AARTEGATVFGYQVMDPERFGVVEFDDN-FRAISLEEKPKQPKSNWA 169
              L           R     +   QV DP ++GVV  D +        EKP++   N+ 
Sbjct: 121 EEILTMYSKLNCDHQRKCEGIILVKQVEDPSKYGVVVHDRDTGLVEEFIEKPQKYIGNFI 180

Query: 170 VTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGF--AWLDTGTH 227
             GLY     ++   +             +I        +L            W D G  
Sbjct: 181 NAGLYILSPSILNLIEPNIA----VSIEKNIFPKIAARKSLYCLRFLTNEINIWADVGIP 236

Query: 228 DSLIEASTFVQT 239
              +  +     
Sbjct: 237 ADFLYGTQLFLK 248


>UniRef50_B2VWC7 Mannose-1-phosphate guanyltransferase n=2 Tax=Leotiomyceta
           RepID=B2VWC7_PYRTR
          Length = 336

 Score =  224 bits (572), Expect = 3e-57,   Method: Composition-based stats.
 Identities = 50/278 (17%), Positives = 95/278 (34%), Gaps = 39/278 (14%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK IIL GG GTRL P+T  + K L+   +KPMI + +  L  AG+ ++++      +  
Sbjct: 1   MKAIILVGGFGTRLRPLTLTLPKPLVEFANKPMIQHQIEALAAAGVTDVVLAVNYRPEIM 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            + L  +                 G              +    VL  ++     F    
Sbjct: 61  AEALKANV---------------LG------------KDDSPFFVLNADVTCDYPFKQLA 93

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNF--RAISLEEKPKQPKSNWAVTGLYFYDS 178
               +  +  T+   +V +P ++GVV        +     EKP +   N    G+Y  ++
Sbjct: 94  EFHKSHGDEGTIVVTKVEEPSKYGVVVHKPGHASKIDRFVEKPVEFVGNRINAGIYIMNT 153

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
            V++  +    S   E          ++ G L          W+D G     +  +    
Sbjct: 154 SVLKRIELRPTSIEQE-----TFPAIVKDGLL--HSFDLEGFWMDVGQPKDFLTGTCLYL 206

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKT 276
           +   R+  K+       +         +   ++ + K 
Sbjct: 207 SSLARKNSKLLTSPSEPY---VYGGNVLIDPSAKIGKN 241


>UniRef50_A4WLA7 Nucleotidyl transferase n=6 Tax=Thermoproteaceae RepID=A4WLA7_PYRAR
          Length = 360

 Score =  224 bits (571), Expect = 3e-57,   Method: Composition-based stats.
 Identities = 58/277 (20%), Positives = 110/277 (39%), Gaps = 15/277 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
           GIILAGG  TRL P++    K L P+  KP+I + +  ++   + E +I          +
Sbjct: 5   GIILAGGFATRLRPLSYTKPKPLFPVLGKPVIDWIIEKVVE--VAEPVISARY-LSSMIR 61

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
             +   S++G ++   E+  P G   A +     L  + +  V   ++F           
Sbjct: 62  SHVA--SKWGGRVRIVEEDRPLGDGGAVVNVVKSLGVKGAITVANGDVFTDISIKDVWEF 119

Query: 123 VAARTEGATVFGYQV--MDPERFGVVEFDDNFRAISLEEKPKQPK-SNWAVTGLYFYDSK 179
              +    T+   +V   +  RFG+   +D+ R     EKPK+P  SN A  G+Y ++ +
Sbjct: 120 HKRKGAAVTIALVEVPPEEVSRFGIALLEDDGRIARFVEKPKEPVGSNLANAGVYIFEPE 179

Query: 180 VVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQT 239
            V    +  P+         I    +E  ++   +      W D GTH   ++A+     
Sbjct: 180 AVAEFPE--PNAGELKIARHIIPRLMEKFDIYGYV--HKGLWFDIGTHIDYLKAN--FAA 233

Query: 240 VEKRQGFKIACLEEIA-WRNGWLDDEGVKRAASSLAK 275
           ++K    + A    +      ++ ++      S +  
Sbjct: 234 LDKCGSCRPAAPSGVKIIPPVYIGEDVAIGPGSVVGP 270


>UniRef50_A6CVH6 Glucose-1-phosphate adenylyltransferase n=1 Tax=Vibrio shilonii AK1
           RepID=A6CVH6_9VIBR
          Length = 437

 Score =  224 bits (571), Expect = 3e-57,   Method: Composition-based stats.
 Identities = 53/275 (19%), Positives = 95/275 (34%), Gaps = 31/275 (11%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDK-PMIYYPLSVLMLAGIREILIITTPEDKGYF 61
            +ILAGG GTRL  +T  ++K  +    K  +I + LS  + +GIR++ ++T    +   
Sbjct: 21  AMILAGGKGTRLKELTSTIAKPAVSFGGKFKIIDFALSNCINSGIRKVGVLTQYMAQDLI 80

Query: 62  QRLL-GDGSEF-----GIQLEYAEQP----SPDGLAQAFIIGETFLNGEP---SCLVLGD 108
             +  G  S +     G+ +  A+Q        G A A       +         L+LG 
Sbjct: 81  SHIQSGWQSSYSALGEGVHIIPAQQRVGENWYRGTADAIYQNLDLIKRHDQTERILILGG 140

Query: 109 NIFFGQGFSPKLRHVAARTEGATVFG--YQVMDPERFGVVEFDDNFRAISLEEKPKQPKS 166
           +  +   +S  +          TV      +     FGV+  +D    I+  EKP  P  
Sbjct: 141 DHIYKMDYSRMINFHVESGADVTVACIQKPIEQASEFGVMGLNDEGDIINFVEKPANPTP 200

Query: 167 N-------WAVTGLYFYDSKVVEYAKQ--VKPSERGELEITSINQMYLEAGNLTVELLGR 217
                       G+Y ++  V++   +  +   +       +I    +   NL   +   
Sbjct: 201 MPNDDSKALISMGIYIFNVDVLDAELRQALTCPDYKHDFGHNIIPSLIGRSNLKGYVFTE 260

Query: 218 ------GFAWLDTGTHDSLIEASTFVQTVEKRQGF 246
                    W D G  D    A+  +         
Sbjct: 261 RGHPGANGYWRDVGHVDEYYAATMDLLAPTPELDI 295


>UniRef50_C6CVH3 Nucleotidyl transferase n=3 Tax=Bacillales RepID=C6CVH3_PAESJ
          Length = 411

 Score =  224 bits (571), Expect = 4e-57,   Method: Composition-based stats.
 Identities = 65/260 (25%), Positives = 106/260 (40%), Gaps = 31/260 (11%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYD-KPMIYYPLSVLMLAGIREILIITTPEDKGYF 61
            ++LAGG G RL P+T  ++K ++P  +   MI +PLS  M +GIR I ++T        
Sbjct: 8   AMLLAGGEGKRLAPLTTALAKPVVPFGEQYRMIDFPLSNCMNSGIRRIGVLTQF-CADTV 66

Query: 62  QRLLGDGSEFGIQLEYAEQPSPDG------------------LAQAFIIGETFLN--GEP 101
            R +G G  + +    A QP   G                   A A     +++      
Sbjct: 67  HRHIGGGEAW-LN---AVQPKHLGEIALLPASVASPNGCYTGTADAIYRNLSYIEQHNPE 122

Query: 102 SCLVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQVM--DPERFGVVEFDDNFRAISLEE 159
             L+L  +  +   + P L         AT+   +V   +  RFG++  ++++  +  EE
Sbjct: 123 HVLILSGDHIYQMDYRPMLEAHIKSGAAATIAVKRVPWHEASRFGILNTNEDYSVVEFEE 182

Query: 160 KPKQPKSNWAVTGLYFYDSKVVE--YAKQVKPSERGELEITSINQMYLEAGNLTVELLGR 217
           KP +P+SN A  G+Y + + ++     K              I  M L+ G         
Sbjct: 183 KPSRPRSNLASMGIYMFRTDMLREVLLKDAGNPVSSHDFGKDIIPMLLQDGASLTAYP-Y 241

Query: 218 GFAWLDTGTHDSLIEASTFV 237
              W D GT DSL EA   +
Sbjct: 242 EGYWRDVGTVDSLWEAHMEL 261


>UniRef50_A2U039 Nucleotidyl transferase n=1 Tax=Polaribacter sp. MED152
           RepID=A2U039_9FLAO
          Length = 348

 Score =  223 bits (569), Expect = 7e-57,   Method: Composition-based stats.
 Identities = 52/239 (21%), Positives = 92/239 (38%), Gaps = 12/239 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +I+AGG GTRL P+T    K LL I +KP++ + L  L L GI +             +
Sbjct: 121 AVIMAGGKGTRLRPLTDNTPKPLLKIGEKPIMEHNLDRLCLYGIDDYWFSVKY-LGEQIE 179

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
              G+G +  I ++Y  + +P G   A    + F       L+   +I     +      
Sbjct: 180 GYFGNGKDKNINIQYVWEDNPLGTIGAVSKIKNF--EHDYILLTNSDILTNLDYEHFFLD 237

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
              +    +V          + V+E  D     S +EKP    + ++  G+Y     V++
Sbjct: 238 FLKQEADFSVVTIPYRVNVPYAVLETSDR-EITSFKEKPS--YTYYSNGGIYLMKKSVLK 294

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVE 241
           Y  +           T + +  ++ G   V        WLD G H+   +A   +  ++
Sbjct: 295 YLPEEVF-----YNATDLMEKLIKEGKKVVSYPLSS-YWLDVGKHEDFEKAQKDINQIK 347


>UniRef50_C6VS96 Nucleotidyl transferase n=1 Tax=Dyadobacter fermentans DSM 18053
           RepID=C6VS96_DYAFD
          Length = 243

 Score =  222 bits (568), Expect = 7e-57,   Method: Composition-based stats.
 Identities = 57/234 (24%), Positives = 96/234 (41%), Gaps = 10/234 (4%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +I+AGG GTRL P+T    K L+P+  KP+I + +  L   G+REI I      +   +
Sbjct: 14  VVIMAGGKGTRLKPLTDNTHKSLIPVGGKPIIRHLIDHLASFGLREIHISVGHLAEQVIE 73

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
             LGDG E G+ L Y ++  P G   A  + + +       LV+  +++           
Sbjct: 74  -YLGDGCEPGVTLRYVKERIPMGSIGALTLKQRW--PHEHFLVINGDVYANFDVHHFCST 130

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
             AR     V          +GV+E + N       EKP+         G+Y ++ KV+ 
Sbjct: 131 YFARQADMAVLAVPNTVKVPYGVLEINQNGDISHFSEKPEYDL--MVNAGVYIFNQKVLN 188

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTF 236
              +         E   + +  + AG     +      W+D G+ ++L +A   
Sbjct: 189 LLPKRIA-----YEGWQLIESAMHAGLHVAGVPQDSGYWIDIGSMETLQKAQEM 237


>UniRef50_A3DK82 Glucose-1-phosphate adenylyltransferase n=73 Tax=Bacteria
           RepID=GLGC_CLOTH
          Length = 426

 Score =  222 bits (567), Expect = 1e-56,   Method: Composition-based stats.
 Identities = 58/302 (19%), Positives = 115/302 (38%), Gaps = 26/302 (8%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDK-PMIYYPLSVLMLAGIREILIITTPEDKGYF 61
            ++LAGG G+RL  +T+ ++K  +    K  +I + LS  + + I  + ++T  +     
Sbjct: 8   ALLLAGGQGSRLGVLTKNIAKPAVLYGGKYRIIDFSLSNCVNSDIDTVGVLTQYQPLEL- 66

Query: 62  QRLLGDGSEF-------GIQLEYAE---Q--PSPDGLAQAFIIGETFLN--GEPSCLVLG 107
              +G G  +       G+ +       +      G A A      +++       ++L 
Sbjct: 67  NAHIGIGKPWDMDRINGGVTILSPYLKAEIGEWYKGTANAVFQNIHYVDKYSPKYVIILS 126

Query: 108 DNIFFGQGFSPKLRHVAARTEGATVFGYQV--MDPERFGVVEFDDNFRAISLEEKPKQPK 165
            +  +   +S  L         AT+    V   +  R+G++   +N +    EEKP+ PK
Sbjct: 127 GDHVYKMNYSQMLDFHKENNADATISVINVPWEEASRYGIMNTYENGKIYEFEEKPQNPK 186

Query: 166 SNWAVTGLYFYDSKVVE--YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLD 223
           SN A  G+Y ++ +V++    +  +  E       +I  M L+ G            W D
Sbjct: 187 SNLASMGVYIFNWEVLKEYLIRDDQNEESAHDFGKNIIPMMLKEGRSMWAY-KFNGYWRD 245

Query: 224 TGTHDSLIEASTFVQTVEKRQGF-----KIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
            GT  +  E++  + +            KI     +   +       VK++  +     Y
Sbjct: 246 VGTIQAYWESNMDLISRVPEFNLFDPAWKIYTPNPVKPAHYIGPTGSVKKSIVAEGCMIY 305

Query: 279 GQ 280
           G 
Sbjct: 306 GS 307


>UniRef50_D2RP80 Nucleotidyl transferase n=2 Tax=Haloterrigena turkmenica DSM 5511
           RepID=D2RP80_9EURY
          Length = 392

 Score =  222 bits (566), Expect = 1e-56,   Method: Composition-based stats.
 Identities = 56/285 (19%), Positives = 105/285 (36%), Gaps = 9/285 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M  ++LAGG G+RL P+T+   K LLP    P++ +    L+ AG+ EI ++     +  
Sbjct: 1   MSAVVLAGGEGSRLRPLTKHRPKPLLPAATTPILEHVFDQLLEAGVTEITVVVGYR-RNR 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            Q   G      + L Y  Q    G   A +  E+ ++G  + +V GD I      S  L
Sbjct: 60  VQAHFGSTYR-NVPLTYVTQDQQLGSGHALLTAESTVDG-TTIVVNGDQIVESTVISDVL 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKV 180
                 +  AT+     +D   +G V  D +     + E P+  ++     G+Y ++  +
Sbjct: 118 EAHDDNSAVATLGLLNRVDVSSYGGVILD-DGEVTEIVENPQDERTYRFNAGVYAFEPAI 176

Query: 181 VEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFV--Q 238
            +  +  +P   GE  +       L +       +     W+D      L++ S  +   
Sbjct: 177 FDAVRAAEPRA-GEQSLIDAINELLASDEAVRGTV-SEGLWVDATYPWDLLDVSFELFEA 234

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLA-KTGYGQYL 282
            +      +          +  + +  V      +      G Y 
Sbjct: 235 GLINGSRTENVAESATVHESAVVREPVVVAPDCEIGAGAVVGPYA 279


>UniRef50_A4XFV3 Nucleotidyl transferase n=1 Tax=Caldicellulosiruptor
           saccharolyticus DSM 8903 RepID=A4XFV3_CALS8
          Length = 677

 Score =  221 bits (565), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 48/244 (19%), Positives = 93/244 (38%), Gaps = 18/244 (7%)

Query: 34  IYYPLSVLMLAGIREILIITTPEDKGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIG 93
           + Y + +L   GI EI                 DGS+FG+++++  +  P G A +    
Sbjct: 1   MEYAVKLLKRHGIYEIGTTLQYHP-DKIMNYFEDGSKFGVKMQHFVEDRPLGTAGSVKNA 59

Query: 94  ETFLNGEPSCLVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFR 153
           ++FL  + + +VL  +       S  ++    +    T+   +V  P  +G+V  D+  R
Sbjct: 60  KSFL--DETFVVLSGDGITNADLSATIKFHKEKKSKVTILLKEVEIPIEYGIVLTDEEGR 117

Query: 154 AISLEEKP--KQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLT 211
                EKP   +  SN A TG+Y  + ++++Y +  KP +        +    L      
Sbjct: 118 IRRFFEKPSWSEVFSNLANTGIYIIEPEILDYIEDGKPFD----FSKDLFPKLLSENVPM 173

Query: 212 VELLGRGFAWLDTGTHDSLIEASTFVQTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAAS 271
                    W D G   S I+A   +        FK+  + ++   + W+ +      + 
Sbjct: 174 YGY-KMEGYWCDIGDIGSYIKAHKDI--------FKLGGILDLDLASSWIGNNCNISNSV 224

Query: 272 SLAK 275
               
Sbjct: 225 KFMG 228


>UniRef50_Q9L385 Glucose-1-phosphate adenylyltransferase n=19 Tax=Clostridiales
           RepID=GLGC_CLOCE
          Length = 426

 Score =  221 bits (565), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 60/320 (18%), Positives = 113/320 (35%), Gaps = 36/320 (11%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDK-PMIYYPLSVLMLAGIREILIITTPEDKG 59
           M  ++LAGG G+RL  +T+ V+K  +    K  +I + LS    +GI  + ++T  +   
Sbjct: 6   MIAMLLAGGQGSRLGVLTKNVAKPAVLYGGKYRIIDFSLSNCTNSGIDTVGVLTQYQPLK 65

Query: 60  YFQRLLGDGSEF-------GIQLEYAE---Q--PSPDGLAQAFIIGETFLN--GEPSCLV 105
                +G G  +       G+ +       +      G A A      +++       ++
Sbjct: 66  L-NAHIGIGKPWDMDRIDGGVTILSPYLKAEMGEWFKGTANAVYQNIQYIDKYSPHYVII 124

Query: 106 LGDNIFFGQGFSPKLRHVAARTEGATVFGYQV--MDPERFGVVEFDDNFRAISLEEKPKQ 163
           L  +  +   +S  L         AT+    V   +  R+G++   +N +    EEKPK 
Sbjct: 125 LSGDHIYKMDYSKMLDFHKENHADATISVINVPYEEASRYGIMNCHENGKIYEFEEKPKN 184

Query: 164 PKSNWAVTGLYFYDSKVVE--YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAW 221
           PKS  A  G+Y +    +     K  + S+       +I    L  G            W
Sbjct: 185 PKSTLASMGVYIFTWSTLREYLIKDNECSDSVNDFGKNIIPAMLGDGKSMWAY-QYSGYW 243

Query: 222 LDTGTHDSLIEASTFVQTVEKRQGF-----KIACLEEIAWRNGWLD----DEGVKRAASS 272
            D GT  +  E++  + +   +        +I     +   +         + +     S
Sbjct: 244 RDVGTIQAFWESNMDLVSRVPQFNLFDPEWRIYTPNPVKPAHYIASSACVKKSIIAEGCS 303

Query: 273 LAKTGY------GQYLLELL 286
           +  T        G Y+ E  
Sbjct: 304 VHGTVINSILFPGAYIEEGA 323


>UniRef50_A3DKS4 Nucleotidyl transferase n=1 Tax=Staphylothermus marinus F1
           RepID=A3DKS4_STAMF
          Length = 372

 Score =  221 bits (564), Expect = 3e-56,   Method: Composition-based stats.
 Identities = 56/308 (18%), Positives = 108/308 (35%), Gaps = 35/308 (11%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +ILAGG G+RL P+T    K ++P+  KP+I + +  L   G     I+         +
Sbjct: 4   AVILAGGIGSRLRPLTLVKPKPMIPLAGKPLIEHIIYWLKHHGFSRF-IVVGKYLGEVIR 62

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
                  +  +++  +        A A  +    +      L+   ++     F    ++
Sbjct: 63  DYFSGRRDVIVRIVDS-----KDTADAVRLVRDDILSND-ILISMGDVICNADFYSFYKY 116

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKP----------------KQPKS 166
                  AT+   +V +P ++GVV  D++ R     EKP                +  +S
Sbjct: 117 HVENDGIATIALKEVDNPLQYGVVFIDEHQRIRHFVEKPASMELYVLSIAFLKSYRSFRS 176

Query: 167 NWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVE-LLGRGFAWLDTG 225
           N   TG Y  +  V+E   +  PS         +    +E G      ++     W D G
Sbjct: 177 NLVNTGFYMINKYVLEIISKY-PSLM--DWGKHVFPYLVEQGYKVYGWIMDNNVYWEDLG 233

Query: 226 THDSLIEASTFVQTVE--------KRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTG 277
             ++ ++A   + + +        +    K+   E    R   +    + R      K+ 
Sbjct: 234 RINNYVKALRDLLSGKIPGFKPAGREVRDKVYIDEGADVRGKIIPPVYIGRNVFIDEKSI 293

Query: 278 YGQYLLEL 285
            G Y+   
Sbjct: 294 IGPYVSIE 301


>UniRef50_D1C4F4 Nucleotidyl transferase n=1 Tax=Sphaerobacter thermophilus DSM
           20745 RepID=D1C4F4_SPHTD
          Length = 337

 Score =  221 bits (563), Expect = 3e-56,   Method: Composition-based stats.
 Identities = 64/293 (21%), Positives = 108/293 (36%), Gaps = 25/293 (8%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M  II   G GTRL P T    K L+ +  KP++ + L  L+   I +++ +T       
Sbjct: 1   MNIIIPVAGLGTRLRPQTWSKPKPLVSVAGKPVLGHVLDRLLALPIDKVVFVTGY-LGDQ 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +  +     F     + EQ    G + A I     + G P+ +V  D       F   L
Sbjct: 60  IEDYVRQNYRFDA--TFVEQKEQLGQSHAIIQARGEVTG-PTLVVFPD-----MLFEADL 111

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDS-- 178
             ++  T    +F  +V DP RFGV+E  +N R   L EKP+   SN A+ G+Y++ +  
Sbjct: 112 DQISGLTADGALFVKEVDDPRRFGVIEV-ENGRITRLVEKPETMVSNLAIVGIYYFRAVE 170

Query: 179 KVVEYAK---QVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAST 235
            + +            +GE  +    Q  ++ G     L      W D G   +L+  + 
Sbjct: 171 DLFDAIDYQMAHNIQTKGEYFLADAIQHMIDQGTHFTYLPVT--VWEDCGNPKALLNTNR 228

Query: 236 FVQTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRA 288
           ++                       +    V    +++     G Y     R 
Sbjct: 229 YLLARLGNH--------VPDIPGAVIVPPVVIDPTATIRNAVIGPYASIGARV 273


>UniRef50_A1RYE8 Nucleotidyl transferase n=1 Tax=Thermofilum pendens Hrk 5
           RepID=A1RYE8_THEPD
          Length = 388

 Score =  221 bits (563), Expect = 3e-56,   Method: Composition-based stats.
 Identities = 48/295 (16%), Positives = 99/295 (33%), Gaps = 30/295 (10%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            ++LAGG G RL P+T    K LLP+ + P++ + LS+L   G  ++++      +    
Sbjct: 5   AVVLAGGKGVRLRPLTLTTPKPLLPVGNVPILDHILSLLYRHGFEKVIVAVNYLGEKIVN 64

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
            L+    + G+++  A   +P   A A     +++  +   LV   ++            
Sbjct: 65  HLVARWMDKGLEIV-APPLNPADTADAVRKCASYI--DEDFLVTMGDVVTNMDLRSFAYF 121

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK-------------------- 162
             +    A++   +V     FG V  D N   +   EKP                     
Sbjct: 122 HESSGSIASIALIEVQSLRDFGAVLLDGNGAVLHFLEKPGVQEMYVASLAFAFTGTSRKV 181

Query: 163 QPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWL 222
              +N A +G Y +   +++  ++            ++    LE        L     W+
Sbjct: 182 NLFANLANSGFYAFRYDILDVLRENPHLM---DFGKNVFPWLLENNYRVKGWLAEETYWI 238

Query: 223 DTGTHDSLIEASTFVQTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTG 277
           D G  +S + A+  +                      ++ +       + +    
Sbjct: 239 DVGRPESYLTANFDLLAGH----ASPLRPYGRFVDGVYVGEGVEVSPGARIIPPV 289


>UniRef50_A7VCP9 Putative uncharacterized protein n=5 Tax=Bacteria
           RepID=A7VCP9_9CLOT
          Length = 444

 Score =  221 bits (563), Expect = 3e-56,   Method: Composition-based stats.
 Identities = 67/320 (20%), Positives = 117/320 (36%), Gaps = 33/320 (10%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK +I+AGG GTR+  +T  + K ++ I   P++   +  L   G  +I++  +      
Sbjct: 1   MKVVIMAGGKGTRISSVTSDIPKPMIKIEGIPVLEREIKCLKDQGFDDIIMTVSH-LGNI 59

Query: 61  FQRLLGDGS--------EFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFF 112
                GDGS         FG+ +EY  +  P G A A    +  L  +   L+L  +  F
Sbjct: 60  IMDYFGDGSGNSPATGKPFGVHIEYYFEKEPLGNAGALFKIKDKLTSD--FLLLNADAMF 117

Query: 113 GQGFSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPK---QPKSNWA 169
              F+  +     R    T+F +    P   G++  D N        K     Q   N  
Sbjct: 118 DVDFNRFVAFHRKRGGLVTLFTHPNSHPYDSGLIVADKNGTVEKWLTKEDARPQYYKNRV 177

Query: 170 VTGLYFYDSKVVEY--AKQ---VKPSERGELEITSINQMYLE--AGNLTVELLGRGFAWL 222
             GL+  + KV+E+         K    G+     +++  L+  AG   +          
Sbjct: 178 NAGLHVINPKVLEFSGIDADLIGKNGANGKPVKVDLDRQLLKPLAGTGKMFCYDSPEYVK 237

Query: 223 DTGTHDSLIEASTFVQTVE--------KRQGFKIACLEEIAWRNGWL----DDEGVKRAA 270
           D GT +         +           K++   +     I    G+L    D E +   A
Sbjct: 238 DMGTPERYYSVCADYKEGRVSGKNLKNKQKAVFLDRDGTINKYVGFLRKIDDFELIDGVA 297

Query: 271 SSLAKTGYGQYLLELLRARP 290
           +++ K     YL  ++  +P
Sbjct: 298 TAIRKINESGYLAIVVTNQP 317


>UniRef50_A8A970 Nucleotidyl transferase n=1 Tax=Ignicoccus hospitalis KIN4/I
           RepID=A8A970_IGNH4
          Length = 355

 Score =  220 bits (562), Expect = 4e-56,   Method: Composition-based stats.
 Identities = 87/280 (31%), Positives = 128/280 (45%), Gaps = 9/280 (3%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+GIILA G G+RL P+T  V K L+P+  KP++ Y +  L      E  ++        
Sbjct: 1   MEGIILAAGKGSRLRPLTLTVPKPLIPVAGKPLVQYGIEQLRGV-GVERAVVVVGWLGEL 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F+ +LGDGS  G++ EY  QP   G+A A        N     LV   +  F   +  K 
Sbjct: 60  FKEVLGDGSALGMRFEYVLQPKRLGVAHAIHTAIVNANVRSPFLVYFGDNVFDDEWVKKF 119

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFY-DSK 179
             V      A V   +V DP RFGV    ++ R +   EKP++P SN+A+TGLY + D +
Sbjct: 120 NSVDEEF-DAFVVLAKVEDPRRFGVPVI-ESGRIVKFVEKPERPPSNYALTGLYAFRDPE 177

Query: 180 VVEYA-KQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
             E    ++KPS RGE EIT +   Y+  G      +     W DTG  + LIEA  F+ 
Sbjct: 178 QYESCFSELKPSWRGEYEITDLLNCYIRRGYDVKYAVV-EGWWKDTGVPEDLIEAMKFIL 236

Query: 239 TVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGY 278
             +     + +   E+  +  ++           L    Y
Sbjct: 237 EKKLIHKVEGSVEGEVVGK-VYVARGATVEG--RLVGPAY 273


>UniRef50_C5A4G3 Sugar-phosphate nucleotydyltransferase n=9 Tax=Archaea
           RepID=C5A4G3_THEGJ
          Length = 413

 Score =  220 bits (562), Expect = 4e-56,   Method: Composition-based stats.
 Identities = 50/254 (19%), Positives = 93/254 (36%), Gaps = 16/254 (6%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIIT-TPEDKGY 60
           K +I  GG  TRL P+T   SK L+ + +KP++ + +  L   G+ E+ +      +   
Sbjct: 4   KAVIPIGGEATRLRPLTIETSKGLVRLLNKPILEHSILSLARDGVEEVYLGVKGYVNYTT 63

Query: 61  FQRLLGDG----SEFG----IQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFF 112
                 +G     ++G    +++ Y  +        A      +       +V+  +  +
Sbjct: 64  LFDYFREGYWLKKKYGLEKEVRIRYMPRYESTTNGDAVWYTMHYYGIREPVVVIQGDNIY 123

Query: 113 GQGFSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEK--PKQPKSNWAV 170
                        +    T+    V D   FGV + DD++R     EK  P++  SN A 
Sbjct: 124 QLNIGEMYEWHRKKGAFMTIALQPVDDVTGFGVAKIDDDYRIEYFVEKPSPEEAPSNLAN 183

Query: 171 TGLYFYDSKVVEYAKQVKPSERGE----LEITSINQMYLEAGNLTVELLGRGFAWLDTGT 226
           TG+Y        + +    +E  E         I    +E G        +   W D GT
Sbjct: 184 TGIYILSKDFWSFLEDEWAAEMREERKLDFGGDIIPALIEHGYAVYGYPMK-GYWFDIGT 242

Query: 227 HDSLIEASTFVQTV 240
            +  + A+ ++   
Sbjct: 243 PERYLRAAMYLLHH 256


>UniRef50_Q9X3S7 Glucose-1-phosphate thymidyl transferase n=1 Tax=Neisseria
           meningitidis RepID=Q9X3S7_NEIME
          Length = 298

 Score =  220 bits (562), Expect = 4e-56,   Method: Composition-based stats.
 Identities = 134/175 (76%), Positives = 155/175 (88%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MKGIILAGGSGTRL+PITRGVSKQLLP+YDKPMIYYPLSVLMLAGIR+IL+IT PED   
Sbjct: 14  MKGIILAGGSGTRLYPITRGVSKQLLPVYDKPMIYYPLSVLMLAGIRDILVITAPEDNAS 73

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
           F+RLLGDGS+FGI + YA QPSPDGLAQAFIIGE F+  +  CLVLGDNIF+GQ F+  L
Sbjct: 74  FKRLLGDGSDFGISISYAVQPSPDGLAQAFIIGEEFIGNDNVCLVLGDNIFYGQSFTQTL 133

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYF 175
           +  AA+T GATVF YQV +PERFGVVEF++NFRA+S+EEKP++PKS+WAVTGLYF
Sbjct: 134 KQAAAQTHGATVFAYQVKNPERFGVVEFNENFRAVSIEEKPQRPKSDWAVTGLYF 188


>UniRef50_P37820 Putative mannose-1-phosphate guanyltransferase n=12
           Tax=Sulfolobaceae RepID=MPG1_SULAC
          Length = 359

 Score =  220 bits (562), Expect = 4e-56,   Method: Composition-based stats.
 Identities = 63/282 (22%), Positives = 111/282 (39%), Gaps = 17/282 (6%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            I+LAGG  TRL P++    K LLP+  KP++ Y L  L  + +  I +           
Sbjct: 4   AIVLAGGYATRLRPLSLTKPKALLPVLGKPLMDYTLYSLASSDVDTIYLSLRVMADKVLD 63

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
            +          +    + S  G A       +  N     +V+  +I+    F+  L +
Sbjct: 64  HVKQLN--LQKNIVSVIEESRLGDAGPLKFINSKYNLSDDVIVVYGDIYAEIDFNKLLEY 121

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
             ++   AT+   QV DP R+GV+  D   R I + EKPK P SN    G+Y +  +++ 
Sbjct: 122 HQSKGCNATLTATQVEDPSRYGVLITDG-HRLIQIIEKPKTPLSNLVNAGIYVFKKELLN 180

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEK 242
               +  S              L + +  V +      W+D G     +  +  + T++ 
Sbjct: 181 KIDGLSIS-------RDFLPKLLVS-DTCVSVYPYKGLWMDIGVPRDYMRINLELLTLKY 232

Query: 243 RQGF-----KIACLEEIAWRNGWLDDEGVKRAASSLAKTGYG 279
            +GF     K++   E+     ++ D       SS+  +  G
Sbjct: 233 PKGFISQSAKVSEKAELFPPF-YIGDNTTVGEGSSIRNSIIG 273


>UniRef50_B3T1I2 Putative Nucleotidyl transferase n=1 Tax=uncultured marine
           microorganism HF4000_010I05 RepID=B3T1I2_9ZZZZ
          Length = 295

 Score =  220 bits (561), Expect = 5e-56,   Method: Composition-based stats.
 Identities = 65/274 (23%), Positives = 116/274 (42%), Gaps = 33/274 (12%)

Query: 2   KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY- 60
           K +I A G GTR  P+T+ V K+LLPI +KPM+ Y +     AGI++++I+ +P  +   
Sbjct: 13  KAVIPAAGLGTRFLPVTKAVPKELLPILEKPMLQYVVEEAAEAGIQQVIIVISPGKESIA 72

Query: 61  --------FQRLLGDGSEFGI-----------QLEYAEQPSPDGLAQAFIIGETFLNGEP 101
                    +R L D    G+            + +  Q +P GL  A +     +  EP
Sbjct: 73  AYFQPQPELERYLADSEAAGLLEKVGHATSLADVSFVIQENPLGLGHAVLTAREAVANEP 132

Query: 102 SCLVLGDNIFFGQG--FSPKLRHVAARTEGATVFGYQV--MDPERFGVVEF----DDNFR 153
             ++L D+I        S  +     R  G  V   ++     + +GVV+     +  ++
Sbjct: 133 FVVILPDDIIAHSPGVVSQMVAVAQRRGAGV-VAVERMPWDRVQNYGVVDASQVEERVYQ 191

Query: 154 AISLEEK--PKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLT 211
              + EK  P++  SN  V G Y    ++ +  ++  P  +GE+++T    + L++  L 
Sbjct: 192 IRGMVEKPPPEEAPSNLTVVGRYILPPEIFDCLERTLPGAKGEIQLTDGLTILLDSQKL- 250

Query: 212 VELLGRGFAWLDTGTHDSLIEASTFVQTVEKRQG 245
                      D GT   L++AS       +   
Sbjct: 251 -YAYEFLGRRYDGGTPLGLLQASLEFALAREDTR 283


>UniRef50_C7PVA0 Nucleotidyl transferase n=3 Tax=Bacteroidetes RepID=C7PVA0_CHIPD
          Length = 330

 Score =  219 bits (560), Expect = 7e-56,   Method: Composition-based stats.
 Identities = 60/290 (20%), Positives = 114/290 (39%), Gaps = 20/290 (6%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           MK II   G+GT+L P T    K L+P+  + ++   +  L+ AGI E + +        
Sbjct: 1   MKAIIPVAGAGTKLRPHTYTQPKALIPLAGRTILSIIIDQLVEAGINEFVFVIGY-LGDK 59

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            Q  +       +   + +Q S +G   A ++    +  +   +VL  +      F   +
Sbjct: 60  IQHYVQQKYPH-LTCHFVQQNSREGTGHAILLTRQVVQDDEILIVL-GDTICEGNFQELI 117

Query: 121 RHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFY--DS 178
                    + +   +V DP  FGV E ++    + + EKP+ PKSN A+ G+Y      
Sbjct: 118 AA-----PVSMLGLKKVDDPRNFGVAELNEENNIVRVVEKPQIPKSNQALVGVYKIKETP 172

Query: 179 KVVEYAKQVKPSERG---ELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEAST 235
           ++ +  +Q    ++    E ++T   Q  +E G            W D G  D+L+E + 
Sbjct: 173 QLYDCLEQNILHQKKSHDEFQLTDALQCMIEHGVTFKTFKVTN--WFDCGRKDTLLETNA 230

Query: 236 FVQTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLEL 285
            + +      +K+      A+ N  +          S+  +  G  +   
Sbjct: 231 ILLS-----KYKMDNNPAQAYENTIIIPPVSIAEGCSIKNSIIGPNVAIG 275


>UniRef50_Q30U75 Nucleotidyl transferase n=3 Tax=Proteobacteria RepID=Q30U75_SULDN
          Length = 234

 Score =  219 bits (560), Expect = 7e-56,   Method: Composition-based stats.
 Identities = 58/243 (23%), Positives = 97/243 (39%), Gaps = 11/243 (4%)

Query: 1   MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 60
           M+ ++LA G G+RL PIT  + K L+PI  KP++ Y L  L  AGI E LI T       
Sbjct: 1   MRALLLAAGIGSRLRPITNTIPKCLVPINGKPLLEYWLKNLSEAGIDEFLINTHHLHVQV 60

Query: 61  FQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKL 120
            +    + S++  ++    +          +    F + EP  LV  DN+ F   F   +
Sbjct: 61  EE--FIESSKYRDKITLVYEKKLLNTGSTLLTNRAFFDNEPFMLVHADNLSFC-DFGKFI 117

Query: 121 RHVAA--RTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDS 178
                       T+  ++  +P   G+VE D+        EK K P SN A   +Y  ++
Sbjct: 118 NAHKNRPNNCDITMMLFKSDNPSSCGIVELDNRGIVQEFYEKVKNPPSNLANGAVYICEA 177

Query: 179 KVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQ 238
            + ++ + +   ++       +   YL  G +            D GT +S   +   V 
Sbjct: 178 SLFDFLECLD--KKEIDFSNDVLPKYL--GKINTYF--NNTYHRDIGTIESYALSQIEVL 231

Query: 239 TVE 241
              
Sbjct: 232 KQN 234


>UniRef50_B1QX92 Nucleotidyl transferase n=3 Tax=Clostridiales RepID=B1QX92_CLOBU
          Length = 347

 Score =  219 bits (560), Expect = 7e-56,   Method: Composition-based stats.
 Identities = 47/223 (21%), Positives = 86/223 (38%), Gaps = 11/223 (4%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +I+AGG GTRL+P T+ + K L+PI DK +I   +      G R        +     +
Sbjct: 122 VVIMAGGKGTRLYPYTQILPKPLIPIGDKSIIERIIERFEEFGCRNFYCTVNYKK-NMIK 180

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
               +  +    + Y E+ +  G A +  + +  +    +  V   +I     +   L++
Sbjct: 181 AYFEELQK-NYDINYVEEDNFLGTAGSLYLLKDKIK--ETFFVSNCDILVEADYEDILKY 237

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
              +    T+          +GV++  +N +     EKP+   S     G Y  +  V+ 
Sbjct: 238 HKKKENKITMVTSLKNYKIPYGVIKLTNNGQVSETIEKPE--YSYLINAGFYVLEPDVLN 295

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTG 225
              + K        IT +  MY++ G        R  +W D G
Sbjct: 296 DIPENKF-----FHITDLINMYIDTGRRVGTYPIRENSWFDMG 333


>UniRef50_Q1J021 Glucose-1-phosphate adenylyltransferase n=5 Tax=Bacteria
           RepID=GLGC_DEIGD
          Length = 413

 Score =  219 bits (560), Expect = 7e-56,   Method: Composition-based stats.
 Identities = 60/313 (19%), Positives = 106/313 (33%), Gaps = 49/313 (15%)

Query: 1   MK----GIILAGGSGTRLHPITRGVSKQLLPIYDK-PMIYYPLSVLMLAGIREILIITTP 55
           MK    G+ILAGG G+RL P+T   SK  +P   K  +I + ++  + +G+  I ++T  
Sbjct: 1   MKPRVLGMILAGGQGSRLAPLTLKRSKPAVPFGGKYRIIDFAINNFINSGVFSIYVLTQY 60

Query: 56  EDKGYFQRLLGDGSEFGIQLE-----------YAEQP----SPDGLAQAFIIGETFLN-- 98
           + +   +  +  G  FG  L+           Y  +        G A A       ++  
Sbjct: 61  KAQSLTE-HIQRGWRFGTFLQDYFITLVPAQMYRYEELGAVWYRGTADAVYQNLHLIDNF 119

Query: 99  GEPSCLVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQVM--DPERFGVVEFDDNFRAIS 156
                 +   +  +       L+         T+  Y +      +FGV++ DD +R   
Sbjct: 120 NADYVAIFSGDHIYKMNVEHMLQAHMDARADVTIAAYPMPRTRAHQFGVMQVDDRWRVTE 179

Query: 157 LEEKPKQPKS-------NWAVTGLYFYDSKVVEYAKQVKPSERGE--LEITSINQMYLEA 207
             EKP+ P         +    G Y +  + +E       S  GE      ++    L  
Sbjct: 180 FLEKPQDPPGLPGDPDTSLTSMGNYIFSRRALEELLHTSISGEGEGFDFGHNVLPRALAD 239

Query: 208 GNLTVELLGR----------GFAWLDTGTHDSLIEASTFVQTVEKRQGFK-----IACLE 252
           G                      W D GT D+  EAS  + +V            +    
Sbjct: 240 GYHVQAYDFHRNPIPGQSSPNLYWRDVGTLDAYFEASMDLVSVNPEFDIYNPQWPLRTSS 299

Query: 253 EIAWRNGWLDDEG 265
           E +    ++ +  
Sbjct: 300 EFSPPAKFVHEAE 312


>UniRef50_Q01PZ9 UDP-glucose pyrophosphorylase n=1 Tax=Candidatus Solibacter
           usitatus Ellin6076 RepID=Q01PZ9_SOLUE
          Length = 308

 Score =  219 bits (560), Expect = 8e-56,   Method: Composition-based stats.
 Identities = 66/279 (23%), Positives = 109/279 (39%), Gaps = 35/279 (12%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            ++   G GTRL P T+   K++LP+  KP++ Y +  L+  GI +IL +T        +
Sbjct: 15  AVVPVAGLGTRLLPATKSQPKEMLPVARKPIVQYVVEELVSNGIEQILFVTGRSKAS-IE 73

Query: 63  RLLG---------------------DGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEP 101
                                    D      +  Y  Q    GL  A +  E F   EP
Sbjct: 74  NHFDHDPELFQALTQANKQDLLSELDVVALKAKFFYTRQRMQRGLGDAIMCAENFAGEEP 133

Query: 102 SCLVLGDNIF----FGQGFSPKLRHVAARTEGATVFGYQV--MDPERFGVVE----FDDN 151
             + LGD+I       +  +       ++     +   +V   +   +G+V+     DD 
Sbjct: 134 FLVALGDSILGLNAVSKAVARMADVFDSKRASCVIAVEEVPAEETRHYGIVQPEAGADDV 193

Query: 152 FRAISLEEK--PKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGN 209
           FR ++L EK  PK   SN A+ G Y +   + +  ++VKP +RGE+++T   Q   E G 
Sbjct: 194 FRVVNLVEKPAPKDAPSNLAIAGRYIFSPVLFDMIRRVKPDKRGEIQLTDAIQFMCEEGR 253

Query: 210 LTVEL-LGRGFAWLDTGTHDSLIEASTFVQTVEKRQGFK 247
             + + L       D G   S  E+       +   G  
Sbjct: 254 RVMAVKLTPEEKRYDIGNFPSYFESFVEFALADPIYGAD 292


>UniRef50_A9H8Q9 Nucleoside-diphosphate-sugar pyrophosphorylase n=1 Tax=Roseobacter
           litoralis Och 149 RepID=A9H8Q9_9RHOB
          Length = 347

 Score =  219 bits (559), Expect = 1e-55,   Method: Composition-based stats.
 Identities = 46/229 (20%), Positives = 89/229 (38%), Gaps = 12/229 (5%)

Query: 3   GIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQ 62
            +++AGG G+RL  +T+   K LL +  +P++   +      G+++ +     + +   +
Sbjct: 122 VVVMAGGLGSRLGDLTKHKPKPLLDVDGEPILEKIIKRYRDDGLKDFIFCVNYKAE-MIR 180

Query: 63  RLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRH 122
              G G   G++++Y E+    G   A  + +  +       V   +I     F   L  
Sbjct: 181 EHFGSGDRLGVKIDYVEEKKRLGTGGALSLID--VAEYDHFFVTNADIMCTTNFRDMLEF 238

Query: 123 VAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVE 182
              +   AT+   +      FGVVE +  F   SL EKP     ++   G Y  D   + 
Sbjct: 239 HLDQDSDATMAVREYEMQIPFGVVETEG-FEIKSLREKPT--YKHFINAGYYVLDKSALA 295

Query: 183 YAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLI 231
           +  + +       ++ S+  +  E    T         W+D G  + L 
Sbjct: 296 HVPRAEF-----FDMPSLFDVLREKKIRTRIYPTT-GDWIDIGRPEDLE 338


  Database: uniref50.fasta
    Posted date:  Mar 8, 2010 10:38 AM
  Number of letters in database: 1,040,396,356
  Number of sequences in database:  3,077,464
  
Lambda     K      H
   0.313    0.178    0.538 

Lambda     K      H
   0.267   0.0545    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,960,949,997
Number of Sequences: 3077464
Number of extensions: 97499568
Number of successful extensions: 245346
Number of sequences better than 1.0e-01: 250
Number of HSP's better than  0.1 without gapping: 2603
Number of HSP's successfully gapped in prelim test: 2457
Number of HSP's that attempted gapping in prelim test: 233102
Number of HSP's gapped (non-prelim): 5502
length of query: 293
length of database: 1,040,396,356
effective HSP length: 127
effective length of query: 166
effective length of database: 649,558,428
effective search space: 107826699048
effective search space used: 107826699048
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.0 bits)
S2: 93 (40.0 bits)
